Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000457-TA|BGIBMGA000457-PA|IPR002007|Haem peroxidase,
animal, IPR010255|Haem peroxidase
(497 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 83 2e-15
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 83 2e-15
U39573-1|AAC50717.1| 712|Homo sapiens salivary peroxidase protein. 65 5e-10
BC107167-1|AAI07168.1| 712|Homo sapiens lactoperoxidase protein. 65 5e-10
BC107166-1|AAI07167.1| 712|Homo sapiens lactoperoxidase protein. 65 5e-10
AY324876-1|AAP72968.1| 712|Homo sapiens lactoperoxidase protein. 65 5e-10
BC114938-1|AAI14939.1| 1551|Homo sapiens dual oxidase 1 protein. 65 6e-10
BC114628-1|AAI14629.1| 1551|Homo sapiens dual oxidase 1 protein. 65 6e-10
AF230495-1|AAF73921.1| 1551|Homo sapiens NADPH thyroid oxidase 1... 65 6e-10
AF213465-1|AAF71295.1| 1551|Homo sapiens dual oxidase protein. 65 6e-10
BC132813-1|AAI32814.1| 515|Homo sapiens peroxidasin homolog (Dr... 64 1e-09
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 64 1e-09
AK131524-1|BAD18663.1| 515|Homo sapiens protein ( Homo sapiens ... 64 1e-09
AK058200-1|BAB71713.1| 494|Homo sapiens protein ( Homo sapiens ... 64 1e-09
X15377-1|CAA33438.1| 745|Homo sapiens protein ( Human gene for ... 64 1e-09
X04876-2|CAA28565.1| 745|Homo sapiens prepro-myeloperoxidase pr... 64 1e-09
S56200-1|AAB25582.1| 745|Homo sapiens myeloperoxidase protein. 64 1e-09
M19507-1|AAA59863.1| 745|Homo sapiens myeloperoxidase protein. 64 1e-09
M17176-1|AAA60346.1| 745|Homo sapiens MPO protein. 64 1e-09
J02694-1|AAA59896.1| 745|Homo sapiens myeloperoxidase protein. 64 1e-09
DQ088846-1|AAY68218.1| 745|Homo sapiens myeloperoxidase protein. 64 1e-09
BC130476-1|AAI30477.1| 745|Homo sapiens myeloperoxidase protein. 64 1e-09
M58151-1|AAA63213.1| 324|Homo sapiens lactoperoxidase protein. 62 4e-09
AF267981-1|AAF78954.1| 1548|Homo sapiens putative NADPH oxidase/... 58 9e-08
AF230496-1|AAF73922.1| 1548|Homo sapiens NADPH thyroid oxidase 2... 58 9e-08
U04636-1|AAA57317.1| 604|Homo sapiens cyclooxygenase-2 protein. 54 9e-07
M90100-1|AAA58433.1| 604|Homo sapiens cyclooxygenase-2 protein. 54 9e-07
L15326-1|AAA35803.1| 604|Homo sapiens endoperoxide synthase typ... 54 9e-07
D28235-1|BAA05698.1| 604|Homo sapiens prostaglandin endoperoxid... 54 9e-07
BC013734-1|AAH13734.1| 604|Homo sapiens prostaglandin-endoperox... 54 9e-07
AY462100-1|AAR23927.1| 604|Homo sapiens cyclooxygenase 2 protein. 54 9e-07
AY382629-1|AAQ75702.1| 604|Homo sapiens prostaglandin-endoperox... 54 9e-07
AY229989-1|AAO38056.1| 604|Homo sapiens prostaglandin-endoperox... 54 9e-07
AL033533-1|CAB41240.1| 604|Homo sapiens prostaglandin-endoperox... 54 9e-07
X14346-1|CAA32530.1| 702|Homo sapiens eosinophil preperoxidase ... 54 1e-06
M29913-1|AAA58458.1| 715|Homo sapiens eosinophil peroxidase pro... 54 1e-06
DQ054598-1|AAY43126.1| 715|Homo sapiens eosinophil peroxidase p... 54 1e-06
AY151286-1|AAN52932.1| 339|Homo sapiens cyclooxygenase 2b protein. 51 8e-06
M31822-1|AAA36439.1| 599|Homo sapiens prostaglandin-endoperoxid... 50 2e-05
S78220-1|AAB21215.1| 599|Homo sapiens prostaglandin endoperoxid... 50 2e-05
S36271-1|AAB22217.1| 599|Homo sapiens prostaglandin G/H synthas... 50 2e-05
S36219-1|AAB22216.1| 562|Homo sapiens prostaglandin G/H synthas... 50 2e-05
M59979-1|AAA03630.1| 599|Homo sapiens prostaglandin endoperoxid... 50 2e-05
DQ180742-1|ABA60099.1| 630|Homo sapiens cyclooxygenase 1b3 prot... 50 2e-05
DQ180741-1|ABA60098.1| 630|Homo sapiens cyclooxygenase 1b2 prot... 50 2e-05
BC029840-1|AAH29840.1| 599|Homo sapiens prostaglandin-endoperox... 50 2e-05
AY449688-1|AAR08907.1| 599|Homo sapiens prostaglandin-endoperox... 50 2e-05
AL359636-8|CAM45741.1| 599|Homo sapiens prostaglandin-endoperox... 50 2e-05
AL359636-7|CAM45740.1| 562|Homo sapiens prostaglandin-endoperox... 50 2e-05
AL162424-12|CAI14714.1| 562|Homo sapiens prostaglandin-endopero... 50 2e-05
AL162424-11|CAI14715.1| 599|Homo sapiens prostaglandin-endopero... 50 2e-05
AF440204-1|AAL33601.1| 599|Homo sapiens prostaglandin-endoperox... 50 2e-05
M25715-1|AAA97517.1| 933|Homo sapiens TPO protein. 49 3e-05
M17755-1|AAA61217.2| 933|Homo sapiens thyroid peroxidase protein. 49 3e-05
J02969-1|AAA61215.1| 933|Homo sapiens TPO protein. 49 3e-05
DQ011222-1|AAY16985.1| 933|Homo sapiens thyroid peroxidase prot... 49 3e-05
BC095448-1|AAH95448.1| 933|Homo sapiens thyroid peroxidase prot... 49 3e-05
AC105450-1|AAX93261.1| 916|Homo sapiens unknown protein. 49 3e-05
AB208960-1|BAD92197.1| 864|Homo sapiens thyroid peroxidase isof... 49 3e-05
Y00406-1|CAA68467.1| 933|Homo sapiens protein ( Human mRNA for ... 47 1e-04
BC009496-1|AAH09496.2| 218|Homo sapiens PXDN protein protein. 43 0.002
X17358-1|CAA35235.1| 876|Homo sapiens protein ( Human mRNA from... 41 0.009
J02970-1|AAA61216.1| 876|Homo sapiens TPO protein. 41 0.009
AF439430-1|AAL74416.1| 760|Homo sapiens thyroid peroxidase prot... 36 0.43
BC092419-1|AAH92419.1| 701|Homo sapiens hypothetical LOC550631 ... 32 4.0
BC051850-1|AAH51850.1| 343|Homo sapiens transmembrane protein i... 32 5.3
AF327923-1|AAK16442.1| 343|Homo sapiens transmembrane protein i... 32 5.3
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 83.4 bits (197), Expect = 2e-15
Identities = 114/455 (25%), Positives = 192/455 (42%), Gaps = 39/455 (8%)
Query: 16 LAKAVY---YDSWEGFQFRLTSSGKEYSLARHIKNNLL-TVGLATDAKLTQLASYYGEFM 71
L K+VY +++ G +G + R + L+ T + D + T + +G+F+
Sbjct: 783 LLKSVYENGFNTPRGINPHRLYNGHALPMPRLVSTTLIGTETVTPDEQFTHMLMQWGQFL 842
Query: 72 AVDVTSTHDILNFV-VNKPYCCKEEGKSDPMCDPNFIPEFDPVHRFSGHKCLN--QTKPM 128
D+ ST L+ + C +DP C IP D R SG +C+ ++ P+
Sbjct: 843 DHDLDSTVVALSQARFSDGQHCSNVCSNDPPCFSVMIPPNDSRAR-SGARCMFFVRSSPV 901
Query: 129 TFQNL-GCIDNSTIPXXXXXXXXXXX-LSNVYEFTAGSLNLVRSYEG--GQLKYEVV--N 182
+ + NS P SNVY T +R G L+ +V +
Sbjct: 902 CGSGMTSLLMNSVYPREQINQLTSYIDASNVYGSTEHEARSIRDLASHRGLLRQGIVQRS 961
Query: 183 GRQF-PSDASDNTTCFIKQAIS------TGCTR-NVPTGVLGSNLFTTWFWRFHNYVAQQ 234
G+ P T C + S G R N G+ +++ T WF R HN +A +
Sbjct: 962 GKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGL--TSMHTLWF-REHNRIATE 1018
Query: 235 LANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMIEDEIILCNSTGFR-DI 293
L LNP WD + ++Y R IV A + Y +LP++LG+ M G I
Sbjct: 1019 LLKLNPHWDGDTIYYETRKIVGAEIQHITYQHWLPKILGEVGMRTLGEYHGYDPGINAGI 1078
Query: 294 YDDTVVPQIALEYAYANRL---LDKNFNLIKE--VPMVNFSLSVQSLAVDDIMSTLTRGS 348
++ + N L LD+NF I + +P+ S + + + L RG
Sbjct: 1079 FNAFATAAFRFGHTLVNPLLYRLDENFQPIAQDHLPLHKAFFSPFRIVNEGGIDPLLRG- 1137
Query: 349 YYQATGK---ADFTVDPDISNVGLGPVQEV-FDIPTADLAKGRYFGLPSYTKYRDFCSGY 404
+ GK ++ +++ V D+ ++ +GR G+P Y YR +C+
Sbjct: 1138 LFGVAGKMRVPSQLLNTELTERLFSMAHTVALDLAAINIQRGRDHGIPPYHDYRVYCN-L 1196
Query: 405 SKKHVDFDDLTDHISDEKIRQ-LKQVYETTEDIEL 438
S H F+DL + I + +IR+ LK++Y +T +I+L
Sbjct: 1197 SAAHT-FEDLKNEIKNPEIREKLKRLYGSTLNIDL 1230
Score = 45.2 bits (102), Expect = 5e-04
Identities = 19/54 (35%), Positives = 32/54 (59%)
Query: 442 QLQEIRKASLALLLCYVGDDVEKIQPKAFVIVGKGNNLVSCDEIPAIDFTHWKE 495
QL +I++ SLA +LC D++ ++Q F + + SCDEIP +D W++
Sbjct: 1278 QLTQIKQTSLARILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQD 1331
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated antigen
MG50 protein.
Length = 1496
Score = 83.4 bits (197), Expect = 2e-15
Identities = 114/455 (25%), Positives = 192/455 (42%), Gaps = 39/455 (8%)
Query: 16 LAKAVY---YDSWEGFQFRLTSSGKEYSLARHIKNNLL-TVGLATDAKLTQLASYYGEFM 71
L K+VY +++ G +G + R + L+ T + D + T + +G+F+
Sbjct: 783 LLKSVYENGFNTPRGINPHRLYNGHALPMPRLVSTTLIGTETVTPDEQFTHMLMQWGQFL 842
Query: 72 AVDVTSTHDILNFV-VNKPYCCKEEGKSDPMCDPNFIPEFDPVHRFSGHKCLN--QTKPM 128
D+ ST L+ + C +DP C IP D R SG +C+ ++ P+
Sbjct: 843 DHDLDSTVVALSQARFSDGQHCSNVCSNDPPCFSVMIPPNDSRAR-SGARCMFFVRSSPV 901
Query: 129 TFQNL-GCIDNSTIPXXXXXXXXXXX-LSNVYEFTAGSLNLVRSYEG--GQLKYEVV--N 182
+ + NS P SNVY T +R G L+ +V +
Sbjct: 902 CGSGMTSLLMNSVYPREQINQLTSYIDASNVYGSTEHEARSIRDLASHRGLLRQGIVQRS 961
Query: 183 GRQF-PSDASDNTTCFIKQAIS------TGCTR-NVPTGVLGSNLFTTWFWRFHNYVAQQ 234
G+ P T C + S G R N G+ +++ T WF R HN +A +
Sbjct: 962 GKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGL--TSMHTLWF-REHNRIATE 1018
Query: 235 LANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMIEDEIILCNSTGFR-DI 293
L LNP WD + ++Y R IV A + Y +LP++LG+ M G I
Sbjct: 1019 LLKLNPHWDGDTIYYETRKIVGAEIQHITYQHWLPKILGEVGMRTLGEYHGYDPGINAGI 1078
Query: 294 YDDTVVPQIALEYAYANRL---LDKNFNLIKE--VPMVNFSLSVQSLAVDDIMSTLTRGS 348
++ + N L LD+NF I + +P+ S + + + L RG
Sbjct: 1079 FNAFATAAFRFGHTLVNPLLYRLDENFQPIAQDHLPLHKAFFSPFRIVNEGGIDPLLRG- 1137
Query: 349 YYQATGK---ADFTVDPDISNVGLGPVQEV-FDIPTADLAKGRYFGLPSYTKYRDFCSGY 404
+ GK ++ +++ V D+ ++ +GR G+P Y YR +C+
Sbjct: 1138 LFGVAGKMRVPSQLLNTELTERLFSMAHTVALDLAAINIQRGRDHGIPPYHDYRVYCN-L 1196
Query: 405 SKKHVDFDDLTDHISDEKIRQ-LKQVYETTEDIEL 438
S H F+DL + I + +IR+ LK++Y +T +I+L
Sbjct: 1197 SAAHT-FEDLKNEIKNPEIREKLKRLYGSTLNIDL 1230
Score = 45.2 bits (102), Expect = 5e-04
Identities = 19/54 (35%), Positives = 32/54 (59%)
Query: 442 QLQEIRKASLALLLCYVGDDVEKIQPKAFVIVGKGNNLVSCDEIPAIDFTHWKE 495
QL +I++ SLA +LC D++ ++Q F + + SCDEIP +D W++
Sbjct: 1278 QLTQIKQTSLARILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQD 1331
>U39573-1|AAC50717.1| 712|Homo sapiens salivary peroxidase protein.
Length = 712
Score = 65.3 bits (152), Expect = 5e-10
Identities = 69/268 (25%), Positives = 124/268 (46%), Gaps = 34/268 (12%)
Query: 222 TWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMIEDE 281
T F R HN +A++L LNP WD E+L+ AR I+ AF + + +YLP +LG DHM +
Sbjct: 384 TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLG-DHM---Q 439
Query: 282 IILCNSTGFRDIYDDTVVPQIALEYAYANRL-----------LDKNF---NLIKEVPMVN 327
+ G Y ++V P+I+ + +A R LD+N+ E+P+
Sbjct: 440 KWIPPYQG----YSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHT 495
Query: 328 FSLSVQSLAVDDIMSTLTRGSYYQATG--KADFTVDPDISNVGLGPVQEV--FDIPTADL 383
+ + D + L RG + + K + + ++ N P + FD+ +
Sbjct: 496 LFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINT 555
Query: 384 AKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKI-RQLKQVYETTEDIEL---- 438
+ R G P Y +R FC + ++L + + + ++L +Y T ++I++
Sbjct: 556 QRCRDHGQPGYNSWRAFCD--LSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGA 613
Query: 439 MAEQLQEIRKASLALLLCYVGDDVEKIQ 466
+AE L E + LL C +G ++I+
Sbjct: 614 IAEPLVERGRVG-PLLACLLGKQFQQIR 640
>BC107167-1|AAI07168.1| 712|Homo sapiens lactoperoxidase protein.
Length = 712
Score = 65.3 bits (152), Expect = 5e-10
Identities = 69/268 (25%), Positives = 124/268 (46%), Gaps = 34/268 (12%)
Query: 222 TWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMIEDE 281
T F R HN +A++L LNP WD E+L+ AR I+ AF + + +YLP +LG DHM +
Sbjct: 384 TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLG-DHM---Q 439
Query: 282 IILCNSTGFRDIYDDTVVPQIALEYAYANRL-----------LDKNF---NLIKEVPMVN 327
+ G Y ++V P+I+ + +A R LD+N+ E+P+
Sbjct: 440 KWIPPYQG----YSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHT 495
Query: 328 FSLSVQSLAVDDIMSTLTRGSYYQATG--KADFTVDPDISNVGLGPVQEV--FDIPTADL 383
+ + D + L RG + + K + + ++ N P + FD+ +
Sbjct: 496 LFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINT 555
Query: 384 AKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKI-RQLKQVYETTEDIEL---- 438
+ R G P Y +R FC + ++L + + + ++L +Y T ++I++
Sbjct: 556 QRCRDHGQPGYNSWRAFCD--LSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGA 613
Query: 439 MAEQLQEIRKASLALLLCYVGDDVEKIQ 466
+AE L E + LL C +G ++I+
Sbjct: 614 IAEPLVERGRVG-PLLACLLGKQFQQIR 640
>BC107166-1|AAI07167.1| 712|Homo sapiens lactoperoxidase protein.
Length = 712
Score = 65.3 bits (152), Expect = 5e-10
Identities = 69/268 (25%), Positives = 124/268 (46%), Gaps = 34/268 (12%)
Query: 222 TWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMIEDE 281
T F R HN +A++L LNP WD E+L+ AR I+ AF + + +YLP +LG DHM +
Sbjct: 384 TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLG-DHM---Q 439
Query: 282 IILCNSTGFRDIYDDTVVPQIALEYAYANRL-----------LDKNF---NLIKEVPMVN 327
+ G Y ++V P+I+ + +A R LD+N+ E+P+
Sbjct: 440 KWIPPYQG----YSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHT 495
Query: 328 FSLSVQSLAVDDIMSTLTRGSYYQATG--KADFTVDPDISNVGLGPVQEV--FDIPTADL 383
+ + D + L RG + + K + + ++ N P + FD+ +
Sbjct: 496 LFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINT 555
Query: 384 AKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKI-RQLKQVYETTEDIEL---- 438
+ R G P Y +R FC + ++L + + + ++L +Y T ++I++
Sbjct: 556 QRCRDHGQPGYNSWRAFCD--LSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGA 613
Query: 439 MAEQLQEIRKASLALLLCYVGDDVEKIQ 466
+AE L E + LL C +G ++I+
Sbjct: 614 IAEPLVERGRVG-PLLACLLGKQFQQIR 640
>AY324876-1|AAP72968.1| 712|Homo sapiens lactoperoxidase protein.
Length = 712
Score = 65.3 bits (152), Expect = 5e-10
Identities = 69/268 (25%), Positives = 124/268 (46%), Gaps = 34/268 (12%)
Query: 222 TWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMIEDE 281
T F R HN +A++L LNP WD E+L+ AR I+ AF + + +YLP +LG DHM +
Sbjct: 384 TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLG-DHM---Q 439
Query: 282 IILCNSTGFRDIYDDTVVPQIALEYAYANRL-----------LDKNF---NLIKEVPMVN 327
+ G Y ++V P+I+ + +A R LD+N+ E+P+
Sbjct: 440 KWIPPYQG----YSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHT 495
Query: 328 FSLSVQSLAVDDIMSTLTRGSYYQATG--KADFTVDPDISNVGLGPVQEV--FDIPTADL 383
+ + D + L RG + + K + + ++ N P + FD+ +
Sbjct: 496 LFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINT 555
Query: 384 AKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKI-RQLKQVYETTEDIEL---- 438
+ R G P Y +R FC + ++L + + + ++L +Y T ++I++
Sbjct: 556 QRCRDHGQPGYNSWRAFCD--LSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGA 613
Query: 439 MAEQLQEIRKASLALLLCYVGDDVEKIQ 466
+AE L E + LL C +G ++I+
Sbjct: 614 IAEPLVERGRVG-PLLACLLGKQFQQIR 640
>BC114938-1|AAI14939.1| 1551|Homo sapiens dual oxidase 1 protein.
Length = 1551
Score = 64.9 bits (151), Expect = 6e-10
Identities = 55/189 (29%), Positives = 89/189 (47%), Gaps = 14/189 (7%)
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKD------- 275
WF R+HN AQ+LA +P W+DE LF AR V+A + + YE+LP L K
Sbjct: 252 WF-RYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFLQKTLPEYTGY 310
Query: 276 HMIEDEIILCNSTGFRDIYDDTVVPQ-IALEYA--YANRLLDKNFNLIKEVPMVN--FSL 330
D I + + T+VP + + A + ++++N ++ + + + N +S
Sbjct: 311 RPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSRALRVCNSYWSR 370
Query: 331 SVQSLAVDDIMSTLTRGSYYQATGKADFTVDPDISNVGLGPVQ-EVFDIPTADLAKGRYF 389
SL + + L G Q + D + D+ + GP++ D + L +GR
Sbjct: 371 EHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTDHLASCLQRGRDL 430
Query: 390 GLPSYTKYR 398
GLPSYTK R
Sbjct: 431 GLPSYTKAR 439
>BC114628-1|AAI14629.1| 1551|Homo sapiens dual oxidase 1 protein.
Length = 1551
Score = 64.9 bits (151), Expect = 6e-10
Identities = 55/189 (29%), Positives = 89/189 (47%), Gaps = 14/189 (7%)
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKD------- 275
WF R+HN AQ+LA +P W+DE LF AR V+A + + YE+LP L K
Sbjct: 252 WF-RYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFLQKTLPEYTGY 310
Query: 276 HMIEDEIILCNSTGFRDIYDDTVVPQ-IALEYA--YANRLLDKNFNLIKEVPMVN--FSL 330
D I + + T+VP + + A + ++++N ++ + + + N +S
Sbjct: 311 RPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSRALRVCNSYWSR 370
Query: 331 SVQSLAVDDIMSTLTRGSYYQATGKADFTVDPDISNVGLGPVQ-EVFDIPTADLAKGRYF 389
SL + + L G Q + D + D+ + GP++ D + L +GR
Sbjct: 371 EHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTDHLASCLQRGRDL 430
Query: 390 GLPSYTKYR 398
GLPSYTK R
Sbjct: 431 GLPSYTKAR 439
>AF230495-1|AAF73921.1| 1551|Homo sapiens NADPH thyroid oxidase 1
protein.
Length = 1551
Score = 64.9 bits (151), Expect = 6e-10
Identities = 55/189 (29%), Positives = 89/189 (47%), Gaps = 14/189 (7%)
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKD------- 275
WF R+HN AQ+LA +P W+DE LF AR V+A + + YE+LP L K
Sbjct: 252 WF-RYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFLQKTLPEYTGY 310
Query: 276 HMIEDEIILCNSTGFRDIYDDTVVPQ-IALEYA--YANRLLDKNFNLIKEVPMVN--FSL 330
D I + + T+VP + + A + ++++N ++ + + + N +S
Sbjct: 311 RPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSRALRVCNSYWSR 370
Query: 331 SVQSLAVDDIMSTLTRGSYYQATGKADFTVDPDISNVGLGPVQ-EVFDIPTADLAKGRYF 389
SL + + L G Q + D + D+ + GP++ D + L +GR
Sbjct: 371 EHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTDHLASCLQRGRDL 430
Query: 390 GLPSYTKYR 398
GLPSYTK R
Sbjct: 431 GLPSYTKAR 439
>AF213465-1|AAF71295.1| 1551|Homo sapiens dual oxidase protein.
Length = 1551
Score = 64.9 bits (151), Expect = 6e-10
Identities = 55/189 (29%), Positives = 89/189 (47%), Gaps = 14/189 (7%)
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKD------- 275
WF R+HN AQ+LA +P W+DE LF AR V+A + + YE+LP L K
Sbjct: 252 WF-RYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFLQKTLPEYTGY 310
Query: 276 HMIEDEIILCNSTGFRDIYDDTVVPQ-IALEYA--YANRLLDKNFNLIKEVPMVN--FSL 330
D I + + T+VP + + A + ++++N ++ + + + N +S
Sbjct: 311 RPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSRALRVCNSYWSR 370
Query: 331 SVQSLAVDDIMSTLTRGSYYQATGKADFTVDPDISNVGLGPVQ-EVFDIPTADLAKGRYF 389
SL + + L G Q + D + D+ + GP++ D + L +GR
Sbjct: 371 EHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTDHLASCLQRGRDL 430
Query: 390 GLPSYTKYR 398
GLPSYTK R
Sbjct: 431 GLPSYTKAR 439
>BC132813-1|AAI32814.1| 515|Homo sapiens peroxidasin homolog
(Drosophila)-like protein.
Length = 515
Score = 64.1 bits (149), Expect = 1e-09
Identities = 62/234 (26%), Positives = 107/234 (45%), Gaps = 21/234 (8%)
Query: 219 LFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMI 278
+ T WF R HN VA +L+ LNP W+ ++ AR IV A + Y +LP+VLG
Sbjct: 169 MHTLWF-REHNRVATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGD---- 223
Query: 279 EDEIILCNSTGFRDIYDDTVVPQIA-LEYAYANRL-------LDKNFNLIKE--VPMVNF 328
+L G+ + ++ A + + + L L+ I E +P
Sbjct: 224 PGTRMLRGYRGYNPNVNAGIINSFATAAFRFGHTLINPILYRLNATLGEISEGHLPFHKA 283
Query: 329 SLSVQSLAVDDIMSTLTRGSY-YQATGKA-DFTVDPDIS-NVGLGPVQEVFDIPTADLAK 385
S + + + + RG + A +A + + P+++ + D + +
Sbjct: 284 LFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSAAVDSAATIIQR 343
Query: 386 GRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQ-LKQVYETTEDIEL 438
GR G+P Y +R FC+ S K +F+DL + I D +IRQ L+++Y + DI+L
Sbjct: 344 GRDHGIPPYVDFRVFCNLTSVK--NFEDLQNEIKDSEIRQKLRKLYGSPGDIDL 395
Score = 46.0 bits (104), Expect = 3e-04
Identities = 18/54 (33%), Positives = 34/54 (62%)
Query: 442 QLQEIRKASLALLLCYVGDDVEKIQPKAFVIVGKGNNLVSCDEIPAIDFTHWKE 495
QL ++++ASL+ +LC GD ++++Q FV + ++C EIP +D W++
Sbjct: 443 QLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQD 496
>AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase protein.
Length = 1463
Score = 64.1 bits (149), Expect = 1e-09
Identities = 62/234 (26%), Positives = 107/234 (45%), Gaps = 21/234 (8%)
Query: 219 LFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMI 278
+ T WF R HN VA +L+ LNP W+ ++ AR IV A + Y +LP+VLG
Sbjct: 970 MHTLWF-REHNRVATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGD---- 1024
Query: 279 EDEIILCNSTGFRDIYDDTVVPQIA-LEYAYANRL-------LDKNFNLIKE--VPMVNF 328
+L G+ + ++ A + + + L L+ I E +P
Sbjct: 1025 PGTRMLRGYRGYNPNVNAGIINSFATAAFRFGHTLINPILYRLNATLGEISEGHLPFHKA 1084
Query: 329 SLSVQSLAVDDIMSTLTRGSY-YQATGKA-DFTVDPDIS-NVGLGPVQEVFDIPTADLAK 385
S + + + + RG + A +A + + P+++ + D + +
Sbjct: 1085 LFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSAAVDSAATIIQR 1144
Query: 386 GRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQ-LKQVYETTEDIEL 438
GR G+P Y +R FC+ S K +F+DL + I D +IRQ L+++Y + DI+L
Sbjct: 1145 GRDHGIPPYVDFRVFCNLTSVK--NFEDLQNEIKDSEIRQKLRKLYGSPGDIDL 1196
Score = 46.0 bits (104), Expect = 3e-04
Identities = 18/54 (33%), Positives = 34/54 (62%)
Query: 442 QLQEIRKASLALLLCYVGDDVEKIQPKAFVIVGKGNNLVSCDEIPAIDFTHWKE 495
QL ++++ASL+ +LC GD ++++Q FV + ++C EIP +D W++
Sbjct: 1244 QLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQD 1297
>AK131524-1|BAD18663.1| 515|Homo sapiens protein ( Homo sapiens
cDNA FLJ43518 fis, clone PERIC2009086, moderately
similar to Homo sapiens melanoma-associated antigen MG50
mRNA. ).
Length = 515
Score = 64.1 bits (149), Expect = 1e-09
Identities = 62/234 (26%), Positives = 107/234 (45%), Gaps = 21/234 (8%)
Query: 219 LFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMI 278
+ T WF R HN VA +L+ LNP W+ ++ AR IV A + Y +LP+VLG
Sbjct: 169 MHTLWF-REHNRVATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGD---- 223
Query: 279 EDEIILCNSTGFRDIYDDTVVPQIA-LEYAYANRL-------LDKNFNLIKE--VPMVNF 328
+L G+ + ++ A + + + L L+ I E +P
Sbjct: 224 PGTRMLRGYRGYNPNVNAGIINSFATAAFRFGHTLINPILYRLNATLGEISEGHLPFHKA 283
Query: 329 SLSVQSLAVDDIMSTLTRGSY-YQATGKA-DFTVDPDIS-NVGLGPVQEVFDIPTADLAK 385
S + + + + RG + A +A + + P+++ + D + +
Sbjct: 284 LFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSAAVDSAATIIQR 343
Query: 386 GRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQ-LKQVYETTEDIEL 438
GR G+P Y +R FC+ S K +F+DL + I D +IRQ L+++Y + DI+L
Sbjct: 344 GRDHGIPPYVDFRVFCNLTSVK--NFEDLQNEIKDSEIRQKLRKLYGSPGDIDL 395
Score = 46.0 bits (104), Expect = 3e-04
Identities = 18/54 (33%), Positives = 34/54 (62%)
Query: 442 QLQEIRKASLALLLCYVGDDVEKIQPKAFVIVGKGNNLVSCDEIPAIDFTHWKE 495
QL ++++ASL+ +LC GD ++++Q FV + ++C EIP +D W++
Sbjct: 443 QLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQD 496
>AK058200-1|BAB71713.1| 494|Homo sapiens protein ( Homo sapiens
cDNA FLJ25471 fis, clone TST09553. ).
Length = 494
Score = 64.1 bits (149), Expect = 1e-09
Identities = 62/234 (26%), Positives = 107/234 (45%), Gaps = 21/234 (8%)
Query: 219 LFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMI 278
+ T WF R HN VA +L+ LNP W+ ++ AR IV A + Y +LP+VLG
Sbjct: 1 MHTLWF-REHNRVATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGD---- 55
Query: 279 EDEIILCNSTGFRDIYDDTVVPQIA-LEYAYANRL-------LDKNFNLIKE--VPMVNF 328
+L G+ + ++ A + + + L L+ I E +P
Sbjct: 56 PGTRMLRGYRGYNPNVNAGIINSFATAAFRFGHTLINPILYRLNATLGEISEGHLPFHKA 115
Query: 329 SLSVQSLAVDDIMSTLTRGSY-YQATGKA-DFTVDPDIS-NVGLGPVQEVFDIPTADLAK 385
S + + + + RG + A +A + + P+++ + D + +
Sbjct: 116 LFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSAAVDSAATIIQR 175
Query: 386 GRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQ-LKQVYETTEDIEL 438
GR G+P Y +R FC+ S K +F+DL + I D +IRQ L+++Y + DI+L
Sbjct: 176 GRDHGIPPYVDFRVFCNLTSVK--NFEDLQNEIKDSEIRQKLRKLYGSPGDIDL 227
Score = 46.0 bits (104), Expect = 3e-04
Identities = 18/54 (33%), Positives = 34/54 (62%)
Query: 442 QLQEIRKASLALLLCYVGDDVEKIQPKAFVIVGKGNNLVSCDEIPAIDFTHWKE 495
QL ++++ASL+ +LC GD ++++Q FV + ++C EIP +D W++
Sbjct: 275 QLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQD 328
>X15377-1|CAA33438.1| 745|Homo sapiens protein ( Human gene for the
light and heavy chains of myeloperoxidase. ).
Length = 745
Score = 63.7 bits (148), Expect = 1e-09
Identities = 66/262 (25%), Positives = 112/262 (42%), Gaps = 22/262 (8%)
Query: 222 TWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMIEDE 281
T R HN +A +L +LNP WD ERL+ AR IV A + Y +YLP VLG M +
Sbjct: 417 TLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRK-- 474
Query: 282 IILCNSTGFRDIYDDTVVPQIALEYAYANRL-------LDKNFNLIK---EVPMVNFSLS 331
L + D D + + Y + L LD + ++ VP+ +
Sbjct: 475 -YLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFA 533
Query: 332 VQSLAVDDIMSTLTRG---SYYQATGKADFTVDPDISNVGLGPVQEVFDIPTADLAKGRY 388
+ ++ + + RG + + + VD + ++ D+P ++ + R
Sbjct: 534 SWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRD 593
Query: 389 FGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKI-RQLKQVYETTEDIELMAEQLQE-- 445
GLP Y +R FC + V L + + K+ R+L + Y T +I++ + E
Sbjct: 594 HGLPGYNAWRRFCGLPQPETV--GQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPL 651
Query: 446 IRKASLA-LLLCYVGDDVEKIQ 466
RK + LL C +G K++
Sbjct: 652 KRKGRVGPLLACIIGTQFRKLR 673
>X04876-2|CAA28565.1| 745|Homo sapiens prepro-myeloperoxidase
protein.
Length = 745
Score = 63.7 bits (148), Expect = 1e-09
Identities = 66/262 (25%), Positives = 112/262 (42%), Gaps = 22/262 (8%)
Query: 222 TWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMIEDE 281
T R HN +A +L +LNP WD ERL+ AR IV A + Y +YLP VLG M +
Sbjct: 417 TLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRK-- 474
Query: 282 IILCNSTGFRDIYDDTVVPQIALEYAYANRL-------LDKNFNLIK---EVPMVNFSLS 331
L + D D + + Y + L LD + ++ VP+ +
Sbjct: 475 -YLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFA 533
Query: 332 VQSLAVDDIMSTLTRG---SYYQATGKADFTVDPDISNVGLGPVQEVFDIPTADLAKGRY 388
+ ++ + + RG + + + VD + ++ D+P ++ + R
Sbjct: 534 SWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRD 593
Query: 389 FGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKI-RQLKQVYETTEDIELMAEQLQE-- 445
GLP Y +R FC + V L + + K+ R+L + Y T +I++ + E
Sbjct: 594 HGLPGYNAWRRFCGLPQPETV--GQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPL 651
Query: 446 IRKASLA-LLLCYVGDDVEKIQ 466
RK + LL C +G K++
Sbjct: 652 KRKGRVGPLLACIIGTQFRKLR 673
>S56200-1|AAB25582.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 63.7 bits (148), Expect = 1e-09
Identities = 66/262 (25%), Positives = 112/262 (42%), Gaps = 22/262 (8%)
Query: 222 TWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMIEDE 281
T R HN +A +L +LNP WD ERL+ AR IV A + Y +YLP VLG M +
Sbjct: 417 TLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRK-- 474
Query: 282 IILCNSTGFRDIYDDTVVPQIALEYAYANRL-------LDKNFNLIK---EVPMVNFSLS 331
L + D D + + Y + L LD + ++ VP+ +
Sbjct: 475 -YLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFA 533
Query: 332 VQSLAVDDIMSTLTRG---SYYQATGKADFTVDPDISNVGLGPVQEVFDIPTADLAKGRY 388
+ ++ + + RG + + + VD + ++ D+P ++ + R
Sbjct: 534 SWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRD 593
Query: 389 FGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKI-RQLKQVYETTEDIELMAEQLQE-- 445
GLP Y +R FC + V L + + K+ R+L + Y T +I++ + E
Sbjct: 594 HGLPGYNAWRRFCGLPQPETV--GQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPL 651
Query: 446 IRKASLA-LLLCYVGDDVEKIQ 466
RK + LL C +G K++
Sbjct: 652 KRKGRVGPLLACIIGTQFRKLR 673
>M19507-1|AAA59863.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 63.7 bits (148), Expect = 1e-09
Identities = 66/262 (25%), Positives = 112/262 (42%), Gaps = 22/262 (8%)
Query: 222 TWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMIEDE 281
T R HN +A +L +LNP WD ERL+ AR IV A + Y +YLP VLG M +
Sbjct: 417 TLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRK-- 474
Query: 282 IILCNSTGFRDIYDDTVVPQIALEYAYANRL-------LDKNFNLIK---EVPMVNFSLS 331
L + D D + + Y + L LD + ++ VP+ +
Sbjct: 475 -YLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFA 533
Query: 332 VQSLAVDDIMSTLTRG---SYYQATGKADFTVDPDISNVGLGPVQEVFDIPTADLAKGRY 388
+ ++ + + RG + + + VD + ++ D+P ++ + R
Sbjct: 534 SWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRD 593
Query: 389 FGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKI-RQLKQVYETTEDIELMAEQLQE-- 445
GLP Y +R FC + V L + + K+ R+L + Y T +I++ + E
Sbjct: 594 HGLPGYNAWRRFCGLPQPETV--GQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPL 651
Query: 446 IRKASLA-LLLCYVGDDVEKIQ 466
RK + LL C +G K++
Sbjct: 652 KRKGRVGPLLACIIGTQFRKLR 673
>M17176-1|AAA60346.1| 745|Homo sapiens MPO protein.
Length = 745
Score = 63.7 bits (148), Expect = 1e-09
Identities = 66/262 (25%), Positives = 112/262 (42%), Gaps = 22/262 (8%)
Query: 222 TWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMIEDE 281
T R HN +A +L +LNP WD ERL+ AR IV A + Y +YLP VLG M +
Sbjct: 417 TLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRK-- 474
Query: 282 IILCNSTGFRDIYDDTVVPQIALEYAYANRL-------LDKNFNLIK---EVPMVNFSLS 331
L + D D + + Y + L LD + ++ VP+ +
Sbjct: 475 -YLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFA 533
Query: 332 VQSLAVDDIMSTLTRG---SYYQATGKADFTVDPDISNVGLGPVQEVFDIPTADLAKGRY 388
+ ++ + + RG + + + VD + ++ D+P ++ + R
Sbjct: 534 SWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRD 593
Query: 389 FGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKI-RQLKQVYETTEDIELMAEQLQE-- 445
GLP Y +R FC + V L + + K+ R+L + Y T +I++ + E
Sbjct: 594 HGLPGYNAWRRFCGLPQPETV--GQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPL 651
Query: 446 IRKASLA-LLLCYVGDDVEKIQ 466
RK + LL C +G K++
Sbjct: 652 KRKGRVGPLLACIIGTQFRKLR 673
>J02694-1|AAA59896.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 63.7 bits (148), Expect = 1e-09
Identities = 66/262 (25%), Positives = 112/262 (42%), Gaps = 22/262 (8%)
Query: 222 TWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMIEDE 281
T R HN +A +L +LNP WD ERL+ AR IV A + Y +YLP VLG M +
Sbjct: 417 TLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRK-- 474
Query: 282 IILCNSTGFRDIYDDTVVPQIALEYAYANRL-------LDKNFNLIK---EVPMVNFSLS 331
L + D D + + Y + L LD + ++ VP+ +
Sbjct: 475 -YLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFA 533
Query: 332 VQSLAVDDIMSTLTRG---SYYQATGKADFTVDPDISNVGLGPVQEVFDIPTADLAKGRY 388
+ ++ + + RG + + + VD + ++ D+P ++ + R
Sbjct: 534 SWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRD 593
Query: 389 FGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKI-RQLKQVYETTEDIELMAEQLQE-- 445
GLP Y +R FC + V L + + K+ R+L + Y T +I++ + E
Sbjct: 594 HGLPGYNAWRRFCGLPQPETV--GQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPL 651
Query: 446 IRKASLA-LLLCYVGDDVEKIQ 466
RK + LL C +G K++
Sbjct: 652 KRKGRVGPLLACIIGTQFRKLR 673
>DQ088846-1|AAY68218.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 63.7 bits (148), Expect = 1e-09
Identities = 66/262 (25%), Positives = 112/262 (42%), Gaps = 22/262 (8%)
Query: 222 TWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMIEDE 281
T R HN +A +L +LNP WD ERL+ AR IV A + Y +YLP VLG M +
Sbjct: 417 TLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRK-- 474
Query: 282 IILCNSTGFRDIYDDTVVPQIALEYAYANRL-------LDKNFNLIK---EVPMVNFSLS 331
L + D D + + Y + L LD + ++ VP+ +
Sbjct: 475 -YLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFA 533
Query: 332 VQSLAVDDIMSTLTRG---SYYQATGKADFTVDPDISNVGLGPVQEVFDIPTADLAKGRY 388
+ ++ + + RG + + + VD + ++ D+P ++ + R
Sbjct: 534 SWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRD 593
Query: 389 FGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKI-RQLKQVYETTEDIELMAEQLQE-- 445
GLP Y +R FC + V L + + K+ R+L + Y T +I++ + E
Sbjct: 594 HGLPGYNAWRRFCGLPQPETV--GQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPL 651
Query: 446 IRKASLA-LLLCYVGDDVEKIQ 466
RK + LL C +G K++
Sbjct: 652 KRKGRVGPLLACIIGTQFRKLR 673
>BC130476-1|AAI30477.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 63.7 bits (148), Expect = 1e-09
Identities = 66/262 (25%), Positives = 112/262 (42%), Gaps = 22/262 (8%)
Query: 222 TWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMIEDE 281
T R HN +A +L +LNP WD ERL+ AR IV A + Y +YLP VLG M +
Sbjct: 417 TLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRK-- 474
Query: 282 IILCNSTGFRDIYDDTVVPQIALEYAYANRL-------LDKNFNLIK---EVPMVNFSLS 331
L + D D + + Y + L LD + ++ VP+ +
Sbjct: 475 -YLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFA 533
Query: 332 VQSLAVDDIMSTLTRG---SYYQATGKADFTVDPDISNVGLGPVQEVFDIPTADLAKGRY 388
+ ++ + + RG + + + VD + ++ D+P ++ + R
Sbjct: 534 SWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRD 593
Query: 389 FGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKI-RQLKQVYETTEDIELMAEQLQE-- 445
GLP Y +R FC + V L + + K+ R+L + Y T +I++ + E
Sbjct: 594 HGLPGYNAWRRFCGLPQPETV--GQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPL 651
Query: 446 IRKASLA-LLLCYVGDDVEKIQ 466
RK + LL C +G K++
Sbjct: 652 KRKGRVGPLLACIIGTQFRKLR 673
>M58151-1|AAA63213.1| 324|Homo sapiens lactoperoxidase protein.
Length = 324
Score = 62.1 bits (144), Expect = 4e-09
Identities = 66/262 (25%), Positives = 121/262 (46%), Gaps = 34/262 (12%)
Query: 228 HNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMIEDEIILCNS 287
HN +A++L LNP WD E+L+ AR I+ AF + + +YLP +LG DHM + +
Sbjct: 2 HNRLARELKRLNPQWDGEKLYQEARKILGAFMQIITFRDYLPILLG-DHM---QKWIPPY 57
Query: 288 TGFRDIYDDTVVPQIALEYAYANRL-----------LDKNF---NLIKEVPMVNFSLSVQ 333
G Y ++V P+I+ + +A R LD+N+ E+P+ +
Sbjct: 58 QG----YSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTW 113
Query: 334 SLAVDDIMSTLTRGSYYQATG--KADFTVDPDISNVGLGPVQEV--FDIPTADLAKGRYF 389
+ D + L RG + + K + + ++ N P + FD+ + + R
Sbjct: 114 RMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDH 173
Query: 390 GLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKI-RQLKQVYETTEDIEL----MAEQLQ 444
G P Y +R FC + ++L + + + ++L +Y T ++I++ +AE L
Sbjct: 174 GQPGYNSWRAFCD--LSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLV 231
Query: 445 EIRKASLALLLCYVGDDVEKIQ 466
E + LL C +G ++I+
Sbjct: 232 ERGRVG-PLLACLLGKQFQQIR 252
>AF267981-1|AAF78954.1| 1548|Homo sapiens putative NADPH
oxidase/peroxidase DUOX2 protein.
Length = 1548
Score = 57.6 bits (133), Expect = 9e-08
Identities = 52/189 (27%), Positives = 85/189 (44%), Gaps = 18/189 (9%)
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGK-------- 274
WF R+HN AQ+LA +P W+DE LF AR V+A + + YE+LP L K
Sbjct: 258 WF-RYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFLQKTLPEYTGY 316
Query: 275 ----DHMIEDEIILCNSTGFRDIYDDTVVPQIALEYAYANRLLDKNFNLIKEVPMVN--F 328
D I E ++ + F + V + A + ++L+K F + + + N +
Sbjct: 317 RPFLDPSISPEFVVASEQFFSTMVPPGVYMRNAS--CHFRKVLNKGFQSSQALRVCNNYW 374
Query: 329 SLSVQSLAVDDIMSTLTRGSYYQATGKADFTVDPDISNVGLGPVQ-EVFDIPTADLAKGR 387
+L ++ L G Q + D V D+ + GP + D + + +GR
Sbjct: 375 IRENPNLNSTQEVNELLLGMASQISELEDNIVVEDLRDYWPGPGKFSRTDYVASSIQRGR 434
Query: 388 YFGLPSYTK 396
GLPSY++
Sbjct: 435 DMGLPSYSQ 443
>AF230496-1|AAF73922.1| 1548|Homo sapiens NADPH thyroid oxidase 2
protein.
Length = 1548
Score = 57.6 bits (133), Expect = 9e-08
Identities = 52/189 (27%), Positives = 85/189 (44%), Gaps = 18/189 (9%)
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGK-------- 274
WF R+HN AQ+LA +P W+DE LF AR V+A + + YE+LP L K
Sbjct: 258 WF-RYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFLQKTLPEYTGY 316
Query: 275 ----DHMIEDEIILCNSTGFRDIYDDTVVPQIALEYAYANRLLDKNFNLIKEVPMVN--F 328
D I E ++ + F + V + A + ++L+K F + + + N +
Sbjct: 317 RPFLDPSISPEFVVASEQFFSTMVPPGVYMRNAS--CHFRKVLNKGFQSSQALRVCNNYW 374
Query: 329 SLSVQSLAVDDIMSTLTRGSYYQATGKADFTVDPDISNVGLGPVQ-EVFDIPTADLAKGR 387
+L ++ L G Q + D V D+ + GP + D + + +GR
Sbjct: 375 IRENPNLNSTQEVNELLLGMASQISELEDNIVVEDLRDYWPGPGKFSRTDYVASSIQRGR 434
Query: 388 YFGLPSYTK 396
GLPSY++
Sbjct: 435 DMGLPSYSQ 443
>U04636-1|AAA57317.1| 604|Homo sapiens cyclooxygenase-2 protein.
Length = 604
Score = 54.4 bits (125), Expect = 9e-07
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 5/125 (4%)
Query: 154 LSNVYEFTAGSLNLVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCTR 208
L+++Y T +R ++ G++KY++++G +P D I + + +
Sbjct: 216 LNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQ 275
Query: 209 NVPTGVLGSNLFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYL 268
V V G ++ T + R HN V L +P W DE+LF T+R I++ +++ +Y+
Sbjct: 276 EVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYV 335
Query: 269 PEVLG 273
+ G
Sbjct: 336 QHLSG 340
>M90100-1|AAA58433.1| 604|Homo sapiens cyclooxygenase-2 protein.
Length = 604
Score = 54.4 bits (125), Expect = 9e-07
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 5/125 (4%)
Query: 154 LSNVYEFTAGSLNLVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCTR 208
L+++Y T +R ++ G++KY++++G +P D I + + +
Sbjct: 216 LNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQ 275
Query: 209 NVPTGVLGSNLFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYL 268
V V G ++ T + R HN V L +P W DE+LF T+R I++ +++ +Y+
Sbjct: 276 EVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYV 335
Query: 269 PEVLG 273
+ G
Sbjct: 336 QHLSG 340
>L15326-1|AAA35803.1| 604|Homo sapiens endoperoxide synthase type
II protein.
Length = 604
Score = 54.4 bits (125), Expect = 9e-07
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 5/125 (4%)
Query: 154 LSNVYEFTAGSLNLVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCTR 208
L+++Y T +R ++ G++KY++++G +P D I + + +
Sbjct: 216 LNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQ 275
Query: 209 NVPTGVLGSNLFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYL 268
V V G ++ T + R HN V L +P W DE+LF T+R I++ +++ +Y+
Sbjct: 276 EVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYV 335
Query: 269 PEVLG 273
+ G
Sbjct: 336 QHLSG 340
>D28235-1|BAA05698.1| 604|Homo sapiens prostaglandin endoperoxide
synthase-2 protein.
Length = 604
Score = 54.4 bits (125), Expect = 9e-07
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 5/125 (4%)
Query: 154 LSNVYEFTAGSLNLVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCTR 208
L+++Y T +R ++ G++KY++++G +P D I + + +
Sbjct: 216 LNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQ 275
Query: 209 NVPTGVLGSNLFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYL 268
V V G ++ T + R HN V L +P W DE+LF T+R I++ +++ +Y+
Sbjct: 276 EVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYV 335
Query: 269 PEVLG 273
+ G
Sbjct: 336 QHLSG 340
>BC013734-1|AAH13734.1| 604|Homo sapiens prostaglandin-endoperoxide
synthase 2 (prostaglandin G/H synthase and cyclooxyg
protein.
Length = 604
Score = 54.4 bits (125), Expect = 9e-07
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 5/125 (4%)
Query: 154 LSNVYEFTAGSLNLVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCTR 208
L+++Y T +R ++ G++KY++++G +P D I + + +
Sbjct: 216 LNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQ 275
Query: 209 NVPTGVLGSNLFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYL 268
V V G ++ T + R HN V L +P W DE+LF T+R I++ +++ +Y+
Sbjct: 276 EVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYV 335
Query: 269 PEVLG 273
+ G
Sbjct: 336 QHLSG 340
>AY462100-1|AAR23927.1| 604|Homo sapiens cyclooxygenase 2 protein.
Length = 604
Score = 54.4 bits (125), Expect = 9e-07
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 5/125 (4%)
Query: 154 LSNVYEFTAGSLNLVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCTR 208
L+++Y T +R ++ G++KY++++G +P D I + + +
Sbjct: 216 LNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQ 275
Query: 209 NVPTGVLGSNLFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYL 268
V V G ++ T + R HN V L +P W DE+LF T+R I++ +++ +Y+
Sbjct: 276 EVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYV 335
Query: 269 PEVLG 273
+ G
Sbjct: 336 QHLSG 340
>AY382629-1|AAQ75702.1| 604|Homo sapiens prostaglandin-endoperoxide
synthase 2 (prostaglandin G/H synthase and cyclooxyg
protein.
Length = 604
Score = 54.4 bits (125), Expect = 9e-07
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 5/125 (4%)
Query: 154 LSNVYEFTAGSLNLVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCTR 208
L+++Y T +R ++ G++KY++++G +P D I + + +
Sbjct: 216 LNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQ 275
Query: 209 NVPTGVLGSNLFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYL 268
V V G ++ T + R HN V L +P W DE+LF T+R I++ +++ +Y+
Sbjct: 276 EVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYV 335
Query: 269 PEVLG 273
+ G
Sbjct: 336 QHLSG 340
>AY229989-1|AAO38056.1| 604|Homo sapiens prostaglandin-endoperoxide
synthase 2 (prostaglandin G/H synthase and cyclooxyg
protein.
Length = 604
Score = 54.4 bits (125), Expect = 9e-07
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 5/125 (4%)
Query: 154 LSNVYEFTAGSLNLVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCTR 208
L+++Y T +R ++ G++KY++++G +P D I + + +
Sbjct: 216 LNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQ 275
Query: 209 NVPTGVLGSNLFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYL 268
V V G ++ T + R HN V L +P W DE+LF T+R I++ +++ +Y+
Sbjct: 276 EVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYV 335
Query: 269 PEVLG 273
+ G
Sbjct: 336 QHLSG 340
>AL033533-1|CAB41240.1| 604|Homo sapiens prostaglandin-endoperoxide
synthase 2 (prostaglandin G/H synthase and cyclooxyg
protein.
Length = 604
Score = 54.4 bits (125), Expect = 9e-07
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 5/125 (4%)
Query: 154 LSNVYEFTAGSLNLVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCTR 208
L+++Y T +R ++ G++KY++++G +P D I + + +
Sbjct: 216 LNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQ 275
Query: 209 NVPTGVLGSNLFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYL 268
V V G ++ T + R HN V L +P W DE+LF T+R I++ +++ +Y+
Sbjct: 276 EVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYV 335
Query: 269 PEVLG 273
+ G
Sbjct: 336 QHLSG 340
>X14346-1|CAA32530.1| 702|Homo sapiens eosinophil preperoxidase (AA
-127 to 575) protein.
Length = 702
Score = 54.0 bits (124), Expect = 1e-06
Identities = 58/255 (22%), Positives = 111/255 (43%), Gaps = 21/255 (8%)
Query: 205 GCTRNVPTGVLGSNLFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFY 264
G TR+ T L + T F R HN +A +L LNP W+ ++L+ AR I+ A + Y
Sbjct: 362 GDTRSTETPKLAA--MHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQIITY 419
Query: 265 YEYLPEVLGKDHMIEDEIILCNSTGFRDIYDDTVVPQIALEYAYANRL-------LDKNF 317
++LP VLGK L + G+ D V L + + + + LD +
Sbjct: 420 RDFLPLVLGK---ARARRTLGHYRGYCSNVDPRVANVFTLAFRFGHTMLQPFMFRLDSQY 476
Query: 318 NLI---KEVPMVNFSLSVQSLAVDDIMSTLTRG--SYYQATGKADFTVDPDISNVGLGPV 372
VP+ + + + + + + RG + + D + ++ + V
Sbjct: 477 RASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQV 536
Query: 373 QEV-FDIPTADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKI-RQLKQVY 430
+ + D+ ++ + R GLP Y +R FC G S+ + L+ + ++ + R+ +Y
Sbjct: 537 RRIGLDLAALNMQRSRDHGLPGYNAWRRFC-GLSQPR-NLAQLSRVLKNQDLARKFLNLY 594
Query: 431 ETTEDIELMAEQLQE 445
T ++I++ + E
Sbjct: 595 GTPDNIDIWIGAIAE 609
>M29913-1|AAA58458.1| 715|Homo sapiens eosinophil peroxidase
protein.
Length = 715
Score = 54.0 bits (124), Expect = 1e-06
Identities = 58/255 (22%), Positives = 111/255 (43%), Gaps = 21/255 (8%)
Query: 205 GCTRNVPTGVLGSNLFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFY 264
G TR+ T L + T F R HN +A +L LNP W+ ++L+ AR I+ A + Y
Sbjct: 374 GDTRSTETPKLAA--MHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQIITY 431
Query: 265 YEYLPEVLGKDHMIEDEIILCNSTGFRDIYDDTVVPQIALEYAYANRL-------LDKNF 317
++LP VLGK L + G+ D V L + + + + LD +
Sbjct: 432 RDFLPLVLGK---ARARRTLGHYRGYCSNVDPRVANVFTLAFRFGHTMLQPFMFRLDSQY 488
Query: 318 NLI---KEVPMVNFSLSVQSLAVDDIMSTLTRG--SYYQATGKADFTVDPDISNVGLGPV 372
VP+ + + + + + + RG + + D + ++ + V
Sbjct: 489 RASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQV 548
Query: 373 QEV-FDIPTADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKI-RQLKQVY 430
+ + D+ ++ + R GLP Y +R FC G S+ + L+ + ++ + R+ +Y
Sbjct: 549 RRIGLDLAALNMQRSRDHGLPGYNAWRRFC-GLSQPR-NLAQLSRVLKNQDLARKFLNLY 606
Query: 431 ETTEDIELMAEQLQE 445
T ++I++ + E
Sbjct: 607 GTPDNIDIWIGAIAE 621
>DQ054598-1|AAY43126.1| 715|Homo sapiens eosinophil peroxidase
protein.
Length = 715
Score = 54.0 bits (124), Expect = 1e-06
Identities = 58/255 (22%), Positives = 111/255 (43%), Gaps = 21/255 (8%)
Query: 205 GCTRNVPTGVLGSNLFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFY 264
G TR+ T L + T F R HN +A +L LNP W+ ++L+ AR I+ A + Y
Sbjct: 374 GDTRSTETPKLAA--MHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQIITY 431
Query: 265 YEYLPEVLGKDHMIEDEIILCNSTGFRDIYDDTVVPQIALEYAYANRL-------LDKNF 317
++LP VLGK L + G+ D V L + + + + LD +
Sbjct: 432 RDFLPLVLGK---ARARRTLGHYRGYCSNVDPRVANVFTLAFRFGHTMLQPFMFRLDSQY 488
Query: 318 NLI---KEVPMVNFSLSVQSLAVDDIMSTLTRG--SYYQATGKADFTVDPDISNVGLGPV 372
VP+ + + + + + + RG + + D + ++ + V
Sbjct: 489 RASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQV 548
Query: 373 QEV-FDIPTADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKI-RQLKQVY 430
+ + D+ ++ + R GLP Y +R FC G S+ + L+ + ++ + R+ +Y
Sbjct: 549 RRIGLDLAALNMQRSRDHGLPGYNAWRRFC-GLSQPR-NLAQLSRVLKNQDLARKFLNLY 606
Query: 431 ETTEDIELMAEQLQE 445
T ++I++ + E
Sbjct: 607 GTPDNIDIWIGAIAE 621
>AY151286-1|AAN52932.1| 339|Homo sapiens cyclooxygenase 2b protein.
Length = 339
Score = 51.2 bits (117), Expect = 8e-06
Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 5/121 (4%)
Query: 154 LSNVYEFTAGSLNLVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCTR 208
L+++Y T +R ++ G++KY++++G +P D I + + +
Sbjct: 216 LNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQ 275
Query: 209 NVPTGVLGSNLFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYL 268
V V G ++ T + R HN V L +P W DE+LF T+R I++ Y
Sbjct: 276 EVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGKQENDLYKTLF 335
Query: 269 P 269
P
Sbjct: 336 P 336
>M31822-1|AAA36439.1| 599|Homo sapiens prostaglandin-endoperoxide
synthase-1 protein.
Length = 599
Score = 50.0 bits (114), Expect = 2e-05
Identities = 52/240 (21%), Positives = 104/240 (43%), Gaps = 11/240 (4%)
Query: 168 VRSYEGGQLKYEVVNGRQFPSDASDNTTCF-----IKQAISTGCTRNVPTGVLGSNLFTT 222
+R ++ G+LKY+V++G +P + I + V + G L+ T
Sbjct: 243 LRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYAT 302
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMIEDEI 282
+ R HN V L +P+W DE+LF T R I++ +++ EY+ ++ G ++ +
Sbjct: 303 LWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDP 362
Query: 283 ILCNSTGFRDIYDDTVVPQIALEYAYANRLLDKNFNLIKEVPMVNFSLSVQSLAVDDIMS 342
L F+ Y + + + Y + + L+ +F + + L S+ VD +
Sbjct: 363 ELLFGVQFQ--YRNRIATEFNHLYHW-HPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVE 419
Query: 343 TLTRGSYYQATGK--ADFTVDPDISNVGLGPVQEVFDIPTADLAKGR-YFGLPSYTKYRD 399
L Q G+ +D I +V + ++E ++ + R FG+ YT +++
Sbjct: 420 ALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQE 479
>S78220-1|AAB21215.1| 599|Homo sapiens prostaglandin endoperoxide
synthase protein.
Length = 599
Score = 49.6 bits (113), Expect = 2e-05
Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Query: 168 VRSYEGGQLKYEVVNGRQFPSDASDNTTCF-----IKQAISTGCTRNVPTGVLGSNLFTT 222
+R ++ G+LKY+V++G +P + I + V + G L+ T
Sbjct: 243 LRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYAT 302
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLG 273
+ R HN V L +P+W DE+LF T R I++ +++ EY+ ++ G
Sbjct: 303 LWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG 353
>S36271-1|AAB22217.1| 599|Homo sapiens prostaglandin G/H synthase
protein.
Length = 599
Score = 49.6 bits (113), Expect = 2e-05
Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Query: 168 VRSYEGGQLKYEVVNGRQFPSDASDNTTCF-----IKQAISTGCTRNVPTGVLGSNLFTT 222
+R ++ G+LKY+V++G +P + I + V + G L+ T
Sbjct: 243 LRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYAT 302
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLG 273
+ R HN V L +P+W DE+LF T R I++ +++ EY+ ++ G
Sbjct: 303 LWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG 353
>S36219-1|AAB22216.1| 562|Homo sapiens prostaglandin G/H synthase
protein.
Length = 562
Score = 49.6 bits (113), Expect = 2e-05
Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Query: 168 VRSYEGGQLKYEVVNGRQFPSDASDNTTCF-----IKQAISTGCTRNVPTGVLGSNLFTT 222
+R ++ G+LKY+V++G +P + I + V + G L+ T
Sbjct: 243 LRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYAT 302
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLG 273
+ R HN V L +P+W DE+LF T R I++ +++ EY+ ++ G
Sbjct: 303 LWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG 353
>M59979-1|AAA03630.1| 599|Homo sapiens prostaglandin endoperoxide
synthase protein.
Length = 599
Score = 49.6 bits (113), Expect = 2e-05
Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Query: 168 VRSYEGGQLKYEVVNGRQFPSDASDNTTCF-----IKQAISTGCTRNVPTGVLGSNLFTT 222
+R ++ G+LKY+V++G +P + I + V + G L+ T
Sbjct: 243 LRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYAT 302
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLG 273
+ R HN V L +P+W DE+LF T R I++ +++ EY+ ++ G
Sbjct: 303 LWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG 353
>DQ180742-1|ABA60099.1| 630|Homo sapiens cyclooxygenase 1b3
protein.
Length = 630
Score = 49.6 bits (113), Expect = 2e-05
Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Query: 168 VRSYEGGQLKYEVVNGRQFPSDASDNTTCF-----IKQAISTGCTRNVPTGVLGSNLFTT 222
+R ++ G+LKY+V++G +P + I + V + G L+ T
Sbjct: 274 LRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYAT 333
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLG 273
+ R HN V L +P+W DE+LF T R I++ +++ EY+ ++ G
Sbjct: 334 LWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG 384
>DQ180741-1|ABA60098.1| 630|Homo sapiens cyclooxygenase 1b2
protein.
Length = 630
Score = 49.6 bits (113), Expect = 2e-05
Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Query: 168 VRSYEGGQLKYEVVNGRQFPSDASDNTTCF-----IKQAISTGCTRNVPTGVLGSNLFTT 222
+R ++ G+LKY+V++G +P + I + V + G L+ T
Sbjct: 274 LRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYAT 333
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLG 273
+ R HN V L +P+W DE+LF T R I++ +++ EY+ ++ G
Sbjct: 334 LWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG 384
>BC029840-1|AAH29840.1| 599|Homo sapiens prostaglandin-endoperoxide
synthase 1 (prostaglandin G/H synthase and cyclooxyg
protein.
Length = 599
Score = 49.6 bits (113), Expect = 2e-05
Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Query: 168 VRSYEGGQLKYEVVNGRQFPSDASDNTTCF-----IKQAISTGCTRNVPTGVLGSNLFTT 222
+R ++ G+LKY+V++G +P + I + V + G L+ T
Sbjct: 243 LRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYAT 302
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLG 273
+ R HN V L +P+W DE+LF T R I++ +++ EY+ ++ G
Sbjct: 303 LWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG 353
>AY449688-1|AAR08907.1| 599|Homo sapiens prostaglandin-endoperoxide
synthase 1 (prostaglandin G/H synthase and cyclooxyg
protein.
Length = 599
Score = 49.6 bits (113), Expect = 2e-05
Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Query: 168 VRSYEGGQLKYEVVNGRQFPSDASDNTTCF-----IKQAISTGCTRNVPTGVLGSNLFTT 222
+R ++ G+LKY+V++G +P + I + V + G L+ T
Sbjct: 243 LRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYAT 302
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLG 273
+ R HN V L +P+W DE+LF T R I++ +++ EY+ ++ G
Sbjct: 303 LWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG 353
>AL359636-8|CAM45741.1| 599|Homo sapiens prostaglandin-endoperoxide
synthase 1 (prostaglandin G/H synthase and cyclooxyg
protein.
Length = 599
Score = 49.6 bits (113), Expect = 2e-05
Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Query: 168 VRSYEGGQLKYEVVNGRQFPSDASDNTTCF-----IKQAISTGCTRNVPTGVLGSNLFTT 222
+R ++ G+LKY+V++G +P + I + V + G L+ T
Sbjct: 243 LRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYAT 302
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLG 273
+ R HN V L +P+W DE+LF T R I++ +++ EY+ ++ G
Sbjct: 303 LWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG 353
>AL359636-7|CAM45740.1| 562|Homo sapiens prostaglandin-endoperoxide
synthase 1 (prostaglandin G/H synthase and cyclooxyg
protein.
Length = 562
Score = 49.6 bits (113), Expect = 2e-05
Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Query: 168 VRSYEGGQLKYEVVNGRQFPSDASDNTTCF-----IKQAISTGCTRNVPTGVLGSNLFTT 222
+R ++ G+LKY+V++G +P + I + V + G L+ T
Sbjct: 243 LRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYAT 302
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLG 273
+ R HN V L +P+W DE+LF T R I++ +++ EY+ ++ G
Sbjct: 303 LWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG 353
>AL162424-12|CAI14714.1| 562|Homo sapiens
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H
synthase and cyclooxyg protein.
Length = 562
Score = 49.6 bits (113), Expect = 2e-05
Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Query: 168 VRSYEGGQLKYEVVNGRQFPSDASDNTTCF-----IKQAISTGCTRNVPTGVLGSNLFTT 222
+R ++ G+LKY+V++G +P + I + V + G L+ T
Sbjct: 243 LRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYAT 302
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLG 273
+ R HN V L +P+W DE+LF T R I++ +++ EY+ ++ G
Sbjct: 303 LWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG 353
>AL162424-11|CAI14715.1| 599|Homo sapiens
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H
synthase and cyclooxyg protein.
Length = 599
Score = 49.6 bits (113), Expect = 2e-05
Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Query: 168 VRSYEGGQLKYEVVNGRQFPSDASDNTTCF-----IKQAISTGCTRNVPTGVLGSNLFTT 222
+R ++ G+LKY+V++G +P + I + V + G L+ T
Sbjct: 243 LRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYAT 302
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLG 273
+ R HN V L +P+W DE+LF T R I++ +++ EY+ ++ G
Sbjct: 303 LWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG 353
>AF440204-1|AAL33601.1| 599|Homo sapiens prostaglandin-endoperoxide
synthase 1 protein.
Length = 599
Score = 49.6 bits (113), Expect = 2e-05
Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Query: 168 VRSYEGGQLKYEVVNGRQFPSDASDNTTCF-----IKQAISTGCTRNVPTGVLGSNLFTT 222
+R ++ G+LKY+V++G +P + I + V + G L+ T
Sbjct: 243 LRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYAT 302
Query: 223 WFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLG 273
+ R HN V L +P+W DE+LF T R I++ +++ EY+ ++ G
Sbjct: 303 LWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG 353
>M25715-1|AAA97517.1| 933|Homo sapiens TPO protein.
Length = 933
Score = 49.2 bits (112), Expect = 3e-05
Identities = 61/269 (22%), Positives = 112/269 (41%), Gaps = 30/269 (11%)
Query: 219 LFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMI 278
L T W R HN +A L LN W + ++ AR +V A H + +Y+P +LG +
Sbjct: 406 LHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQ 464
Query: 279 EDEIILCNSTGFRDIYDDTVVPQI-------ALEYAYAN-----RLLDKNFNLIKEVP-- 324
+ G + YD T P + A + +A R LD +F ++P
Sbjct: 465 Q-------YVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGL 517
Query: 325 -MVNFSLSVQSLAVDDIMSTLTRGSYYQAT--GKADFTVDPDIS-NVGLGPVQEVFDIPT 380
+ S +L + L RG + D ++ +++ + + D+ +
Sbjct: 518 WLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLAS 577
Query: 381 ADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQLKQVYETTEDIELMA 440
+L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I++
Sbjct: 578 INLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWL 636
Query: 441 EQLQE---IRKASLALLLCYVGDDVEKIQ 466
L E R + L C +G ++ ++
Sbjct: 637 GGLAENFLPRARTGPLFACLIGKQMKALR 665
>M17755-1|AAA61217.2| 933|Homo sapiens thyroid peroxidase protein.
Length = 933
Score = 49.2 bits (112), Expect = 3e-05
Identities = 61/269 (22%), Positives = 112/269 (41%), Gaps = 30/269 (11%)
Query: 219 LFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMI 278
L T W R HN +A L LN W + ++ AR +V A H + +Y+P +LG +
Sbjct: 406 LHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQ 464
Query: 279 EDEIILCNSTGFRDIYDDTVVPQI-------ALEYAYAN-----RLLDKNFNLIKEVP-- 324
+ G + YD T P + A + +A R LD +F ++P
Sbjct: 465 Q-------YVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGL 517
Query: 325 -MVNFSLSVQSLAVDDIMSTLTRGSYYQAT--GKADFTVDPDIS-NVGLGPVQEVFDIPT 380
+ S +L + L RG + D ++ +++ + + D+ +
Sbjct: 518 WLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLAS 577
Query: 381 ADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQLKQVYETTEDIELMA 440
+L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I++
Sbjct: 578 INLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWL 636
Query: 441 EQLQE---IRKASLALLLCYVGDDVEKIQ 466
L E R + L C +G ++ ++
Sbjct: 637 GGLAENFLPRARTGPLFACLIGKQMKALR 665
>J02969-1|AAA61215.1| 933|Homo sapiens TPO protein.
Length = 933
Score = 49.2 bits (112), Expect = 3e-05
Identities = 61/269 (22%), Positives = 112/269 (41%), Gaps = 30/269 (11%)
Query: 219 LFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMI 278
L T W R HN +A L LN W + ++ AR +V A H + +Y+P +LG +
Sbjct: 406 LHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQ 464
Query: 279 EDEIILCNSTGFRDIYDDTVVPQI-------ALEYAYAN-----RLLDKNFNLIKEVP-- 324
+ G + YD T P + A + +A R LD +F ++P
Sbjct: 465 Q-------YVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGL 517
Query: 325 -MVNFSLSVQSLAVDDIMSTLTRGSYYQAT--GKADFTVDPDIS-NVGLGPVQEVFDIPT 380
+ S +L + L RG + D ++ +++ + + D+ +
Sbjct: 518 WLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLAS 577
Query: 381 ADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQLKQVYETTEDIELMA 440
+L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I++
Sbjct: 578 INLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWL 636
Query: 441 EQLQE---IRKASLALLLCYVGDDVEKIQ 466
L E R + L C +G ++ ++
Sbjct: 637 GGLAENFLPRARTGPLFACLIGKQMKALR 665
>DQ011222-1|AAY16985.1| 933|Homo sapiens thyroid peroxidase
protein.
Length = 933
Score = 49.2 bits (112), Expect = 3e-05
Identities = 61/269 (22%), Positives = 112/269 (41%), Gaps = 30/269 (11%)
Query: 219 LFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMI 278
L T W R HN +A L LN W + ++ AR +V A H + +Y+P +LG +
Sbjct: 406 LHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQ 464
Query: 279 EDEIILCNSTGFRDIYDDTVVPQI-------ALEYAYAN-----RLLDKNFNLIKEVP-- 324
+ G + YD T P + A + +A R LD +F ++P
Sbjct: 465 Q-------YVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGL 517
Query: 325 -MVNFSLSVQSLAVDDIMSTLTRGSYYQAT--GKADFTVDPDIS-NVGLGPVQEVFDIPT 380
+ S +L + L RG + D ++ +++ + + D+ +
Sbjct: 518 WLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLAS 577
Query: 381 ADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQLKQVYETTEDIELMA 440
+L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I++
Sbjct: 578 INLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWL 636
Query: 441 EQLQE---IRKASLALLLCYVGDDVEKIQ 466
L E R + L C +G ++ ++
Sbjct: 637 GGLAENFLPRARTGPLFACLIGKQMKALR 665
>BC095448-1|AAH95448.1| 933|Homo sapiens thyroid peroxidase
protein.
Length = 933
Score = 49.2 bits (112), Expect = 3e-05
Identities = 61/269 (22%), Positives = 112/269 (41%), Gaps = 30/269 (11%)
Query: 219 LFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMI 278
L T W R HN +A L LN W + ++ AR +V A H + +Y+P +LG +
Sbjct: 406 LHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQ 464
Query: 279 EDEIILCNSTGFRDIYDDTVVPQI-------ALEYAYAN-----RLLDKNFNLIKEVP-- 324
+ G + YD T P + A + +A R LD +F ++P
Sbjct: 465 Q-------YVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGL 517
Query: 325 -MVNFSLSVQSLAVDDIMSTLTRGSYYQAT--GKADFTVDPDIS-NVGLGPVQEVFDIPT 380
+ S +L + L RG + D ++ +++ + + D+ +
Sbjct: 518 WLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLAS 577
Query: 381 ADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQLKQVYETTEDIELMA 440
+L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I++
Sbjct: 578 INLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWL 636
Query: 441 EQLQE---IRKASLALLLCYVGDDVEKIQ 466
L E R + L C +G ++ ++
Sbjct: 637 GGLAENFLPRARTGPLFACLIGKQMKALR 665
>AC105450-1|AAX93261.1| 916|Homo sapiens unknown protein.
Length = 916
Score = 49.2 bits (112), Expect = 3e-05
Identities = 61/269 (22%), Positives = 112/269 (41%), Gaps = 30/269 (11%)
Query: 219 LFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMI 278
L T W R HN +A L LN W + ++ AR +V A H + +Y+P +LG +
Sbjct: 406 LHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQ 464
Query: 279 EDEIILCNSTGFRDIYDDTVVPQI-------ALEYAYAN-----RLLDKNFNLIKEVP-- 324
+ G + YD T P + A + +A R LD +F ++P
Sbjct: 465 Q-------YVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGL 517
Query: 325 -MVNFSLSVQSLAVDDIMSTLTRGSYYQAT--GKADFTVDPDIS-NVGLGPVQEVFDIPT 380
+ S +L + L RG + D ++ +++ + + D+ +
Sbjct: 518 WLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLAS 577
Query: 381 ADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQLKQVYETTEDIELMA 440
+L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I++
Sbjct: 578 INLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWL 636
Query: 441 EQLQE---IRKASLALLLCYVGDDVEKIQ 466
L E R + L C +G ++ ++
Sbjct: 637 GGLAENFLPRARTGPLFACLIGKQMKALR 665
>AB208960-1|BAD92197.1| 864|Homo sapiens thyroid peroxidase isoform
d variant protein.
Length = 864
Score = 49.2 bits (112), Expect = 3e-05
Identities = 61/269 (22%), Positives = 112/269 (41%), Gaps = 30/269 (11%)
Query: 219 LFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMI 278
L T W R HN +A L LN W + ++ AR +V A H + +Y+P +LG +
Sbjct: 335 LHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQ 393
Query: 279 EDEIILCNSTGFRDIYDDTVVPQI-------ALEYAYAN-----RLLDKNFNLIKEVP-- 324
+ G + YD T P + A + +A R LD +F ++P
Sbjct: 394 Q-------YVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGL 446
Query: 325 -MVNFSLSVQSLAVDDIMSTLTRGSYYQAT--GKADFTVDPDIS-NVGLGPVQEVFDIPT 380
+ S +L + L RG + D ++ +++ + + D+ +
Sbjct: 447 WLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLAS 506
Query: 381 ADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQLKQVYETTEDIELMA 440
+L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I++
Sbjct: 507 INLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWL 565
Query: 441 EQLQE---IRKASLALLLCYVGDDVEKIQ 466
L E R + L C +G ++ ++
Sbjct: 566 GGLAENFLPRARTGPLFACLIGKQMKALR 594
>Y00406-1|CAA68467.1| 933|Homo sapiens protein ( Human mRNA for
thyroperoxidase. ).
Length = 933
Score = 47.2 bits (107), Expect = 1e-04
Identities = 60/269 (22%), Positives = 112/269 (41%), Gaps = 30/269 (11%)
Query: 219 LFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKDHMI 278
L T W R HN +A L LN W + ++ AR +V A H + +Y+P +LG +
Sbjct: 406 LHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQ 464
Query: 279 EDEIILCNSTGFRDIYDDTVVPQI-------ALEYAYAN-----RLLDKNFNLIKEVP-- 324
+ G + YD T P + A + +A R LD +F ++P
Sbjct: 465 Q-------YVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGL 517
Query: 325 -MVNFSLSVQSLAVDDIMSTLTRGSYYQAT--GKADFTVDPDIS-NVGLGPVQEVFDIPT 380
+ S +L + L RG + D ++ +++ + + ++ +
Sbjct: 518 WLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLNLAS 577
Query: 381 ADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQLKQVYETTEDIELMA 440
+L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I++
Sbjct: 578 INLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWL 636
Query: 441 EQLQE---IRKASLALLLCYVGDDVEKIQ 466
L E R + L C +G ++ ++
Sbjct: 637 GGLAENFLPRARTGPLFACLIGKQMKALR 665
>BC009496-1|AAH09496.2| 218|Homo sapiens PXDN protein protein.
Length = 218
Score = 43.2 bits (97), Expect = 0.002
Identities = 18/53 (33%), Positives = 31/53 (58%)
Query: 443 LQEIRKASLALLLCYVGDDVEKIQPKAFVIVGKGNNLVSCDEIPAIDFTHWKE 495
L +I++ SLA +LC D++ ++Q F + + SCDEIP +D W++
Sbjct: 2 LTQIKQTSLARILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQD 54
>X17358-1|CAA35235.1| 876|Homo sapiens protein ( Human mRNA from
alternatively spliced TPO-2 gene for thyroid peroxidase
(EC.1.11.1.7). ).
Length = 876
Score = 41.1 bits (92), Expect = 0.009
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 219 LFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKD 275
L T W R HN +A L LN W + ++ AR +V A H + +Y+P +LG +
Sbjct: 406 LHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPE 461
>J02970-1|AAA61216.1| 876|Homo sapiens TPO protein.
Length = 876
Score = 41.1 bits (92), Expect = 0.009
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 219 LFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMFYYEYLPEVLGKD 275
L T W R HN +A L LN W + ++ AR +V A H + +Y+P +LG +
Sbjct: 406 LHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPE 461
>AF439430-1|AAL74416.1| 760|Homo sapiens thyroid peroxidase
protein.
Length = 760
Score = 35.5 bits (78), Expect = 0.43
Identities = 23/93 (24%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Query: 377 DIPTADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQLKQVYETTEDI 436
D+ + +L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I
Sbjct: 401 DLASINLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNI 459
Query: 437 ELMAEQLQE---IRKASLALLLCYVGDDVEKIQ 466
++ L E R + L C +G ++ ++
Sbjct: 460 DVWLGGLAENFLPRARTGPLFACLIGKQMKALR 492
>BC092419-1|AAH92419.1| 701|Homo sapiens hypothetical LOC550631
protein.
Length = 701
Score = 32.3 bits (70), Expect = 4.0
Identities = 17/54 (31%), Positives = 35/54 (64%), Gaps = 2/54 (3%)
Query: 424 RQLKQVYETTEDIELMAEQLQE--IRKASLALLLCYVGDDVEKIQPKAFVIVGK 475
R+LKQ E+T+ +E A+QLQE R+A+ + + + V++++ + ++VG+
Sbjct: 311 RELKQQRESTQAVEAKAQQLQEEGERRAAAERQVQQLEEQVQQLEAQVQLLVGR 364
>BC051850-1|AAH51850.1| 343|Homo sapiens transmembrane protein
induced by tumor necrosis factor alpha protein.
Length = 343
Score = 31.9 bits (69), Expect = 5.3
Identities = 16/65 (24%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Query: 206 CTRNVPTGVLGSN--LFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMF 263
CT + +L +N W W FH+YV+ L+ + +W D ++ R+ ++F +
Sbjct: 173 CTLTIRESILINNGSRIKGW-WVFHHYVSAFLSGVMLTWPDGLMYQKFRNQFLSFSMYQS 231
Query: 264 YYEYL 268
+ ++L
Sbjct: 232 FVQFL 236
>AF327923-1|AAK16442.1| 343|Homo sapiens transmembrane protein
induced by tumor necrosis factor alpha protein.
Length = 343
Score = 31.9 bits (69), Expect = 5.3
Identities = 16/65 (24%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Query: 206 CTRNVPTGVLGSN--LFTTWFWRFHNYVAQQLANLNPSWDDERLFYTARDIVVAFHLQMF 263
CT + +L +N W W FH+YV+ L+ + +W D ++ R+ ++F +
Sbjct: 173 CTLTIRESILINNGSRIKGW-WVFHHYVSTFLSGVMLTWPDGLMYQKFRNQFLSFSMYQS 231
Query: 264 YYEYL 268
+ ++L
Sbjct: 232 FVQFL 236
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.137 0.414
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 70,928,958
Number of Sequences: 224733
Number of extensions: 2940451
Number of successful extensions: 10306
Number of sequences better than 10.0: 67
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 10144
Number of HSP's gapped (non-prelim): 133
length of query: 497
length of database: 73,234,838
effective HSP length: 93
effective length of query: 404
effective length of database: 52,334,669
effective search space: 21143206276
effective search space used: 21143206276
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 67 (31.1 bits)
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