Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000456-TA|BGIBMGA000456-PA|IPR001680|WD-40 repeat,
IPR011046|WD40-like, IPR000209|Peptidase S8 and S53, subtilisin,
kexin, sedolisin
(1448 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC127949-1|AAI27950.1| 314|Homo sapiens similar to hypothetical... 107 3e-22
AL354928-6|CAI39637.1| 314|Homo sapiens WD repeat domain 38 pro... 105 9e-22
BC117246-1|AAI17247.1| 707|Homo sapiens F-box and WD repeat dom... 103 5e-21
BC117244-1|AAI17245.1| 707|Homo sapiens F-box and WD repeat dom... 103 5e-21
BC037320-1|AAH37320.1| 621|Homo sapiens FBXW7 protein protein. 103 5e-21
AY049984-1|AAL07271.1| 707|Homo sapiens F-box protein CDC4 prot... 103 5e-21
AY033553-1|AAK57547.1| 627|Homo sapiens F-box protein FBW7 prot... 103 5e-21
AY008274-1|AAG16640.1| 589|Homo sapiens F-box protein SEL10 pro... 103 5e-21
AK223449-1|BAD97169.1| 627|Homo sapiens F-box protein FBW7 isof... 103 5e-21
AK001933-1|BAA91986.1| 553|Homo sapiens protein ( Homo sapiens ... 103 5e-21
AF411972-1|AAL06291.1| 627|Homo sapiens archipelago beta form p... 103 5e-21
AF411971-1|AAL06290.1| 707|Homo sapiens archipelago alpha form ... 103 5e-21
AF383178-1|AAK60269.1| 561|Homo sapiens F-box protein FBX30 pro... 103 5e-21
AB209725-1|BAD92962.1| 624|Homo sapiens F-box protein FBW7 isof... 103 5e-21
BC026213-1|AAH26213.1| 529|Homo sapiens F-box and WD repeat dom... 102 8e-21
AF176022-1|AAF04528.1| 542|Homo sapiens F-box protein Fbw1b pro... 102 8e-21
AB033281-1|BAA92331.1| 542|Homo sapiens F-box and WD-repeats pr... 102 8e-21
AB033280-1|BAA92330.1| 529|Homo sapiens F-box and WD-repeats pr... 102 8e-21
AB033279-1|BAA92329.1| 508|Homo sapiens F-box and WD-repeats pr... 102 8e-21
AB014596-1|BAA31671.1| 550|Homo sapiens KIAA0696 protein protein. 102 8e-21
Y14153-1|CAA74572.1| 569|Homo sapiens beta-transducin repeats c... 101 3e-20
BC027994-1|AAH27994.1| 605|Homo sapiens beta-transducin repeat ... 101 3e-20
AL627424-18|CAI41043.1| 569|Homo sapiens beta-transducin repeat... 101 3e-20
AL627424-17|CAI41042.1| 605|Homo sapiens beta-transducin repeat... 101 3e-20
AL445463-3|CAI12964.1| 569|Homo sapiens beta-transducin repeat ... 101 3e-20
AL445463-2|CAI12963.1| 605|Homo sapiens beta-transducin repeat ... 101 3e-20
AL133387-2|CAH70019.1| 569|Homo sapiens beta-transducin repeat ... 101 3e-20
AL133387-1|CAH70020.1| 605|Homo sapiens beta-transducin repeat ... 101 3e-20
AF129530-1|AAF04464.1| 569|Homo sapiens F-box protein Fbw1A pro... 101 3e-20
AF101784-1|AAD08702.1| 605|Homo sapiens b-TRCP variant E3RS-Ika... 101 3e-20
BX649632-1|CAI18774.1| 334|Homo sapiens WD repeat domain 5 prot... 97 3e-19
BC001635-1|AAH01635.1| 334|Homo sapiens WD repeat domain 5 prot... 97 3e-19
AK000552-1|BAA91248.1| 334|Homo sapiens protein ( Homo sapiens ... 97 3e-19
AJ011376-1|CAB66159.1| 362|Homo sapiens hypothetical protein pr... 97 3e-19
BC106004-1|AAI06005.1| 514|Homo sapiens pleiotropic regulator 1... 94 3e-18
BC020786-1|AAH20786.1| 505|Homo sapiens PLRG1 protein protein. 94 3e-18
AF044333-1|AAD09407.1| 514|Homo sapiens pleiotropic regulator 1... 94 3e-18
AB209111-1|BAD92348.1| 487|Homo sapiens Notchless gene homolog ... 94 3e-18
BC012075-1|AAH12075.1| 485|Homo sapiens notchless homolog 1 (Dr... 93 5e-18
BC002884-1|AAH02884.2| 484|Homo sapiens NLE1 protein protein. 93 5e-18
AK001320-1|BAA91621.1| 485|Homo sapiens protein ( Homo sapiens ... 93 5e-18
BC036377-1|AAH36377.1| 415|Homo sapiens WD repeat domain 69 pro... 91 4e-17
AK097409-1|BAC05039.1| 415|Homo sapiens protein ( Homo sapiens ... 91 4e-17
AC073065-2|AAX93215.1| 415|Homo sapiens unknown protein. 91 4e-17
CR457105-1|CAG33386.1| 521|Homo sapiens PRPF4 protein. 90 5e-17
BC007424-1|AAH07424.1| 521|Homo sapiens PRP4 pre-mRNA processin... 90 5e-17
BC001588-1|AAH01588.1| 522|Homo sapiens PRP4 pre-mRNA processin... 90 5e-17
AY572489-1|AAS78572.1| 521|Homo sapiens 60 kDa U4/U6 snRNP-spec... 90 5e-17
AL449305-8|CAI10969.1| 521|Homo sapiens PRP4 pre-mRNA processin... 90 5e-17
AL449305-7|CAI10968.1| 522|Homo sapiens PRP4 pre-mRNA processin... 90 5e-17
AF016369-1|AAC51925.1| 522|Homo sapiens U4/U6 small nuclear rib... 90 5e-17
AB209797-1|BAD93034.1| 537|Homo sapiens PRPF4 protein variant p... 90 5e-17
CR457279-1|CAG33560.1| 330|Homo sapiens WDR5B protein. 89 8e-17
BC043494-1|AAH43494.1| 330|Homo sapiens WD repeat domain 5B pro... 89 8e-17
AK098821-1|BAC05425.1| 415|Homo sapiens protein ( Homo sapiens ... 89 1e-16
AK002149-1|BAA92110.1| 330|Homo sapiens protein ( Homo sapiens ... 89 1e-16
BC028628-1|AAH28628.1| 375|Homo sapiens WDR71 protein protein. 87 4e-16
BC021541-1|AAH21541.1| 392|Homo sapiens WD repeat domain 71 pro... 87 4e-16
BC006142-1|AAH06142.2| 392|Homo sapiens WD repeat domain 71 pro... 87 4e-16
AK021910-1|BAB13933.1| 392|Homo sapiens protein ( Homo sapiens ... 87 4e-16
AF090988-1|AAC69625.1| 357|Homo sapiens U5 snRNP-specific 40 kD... 87 4e-16
AF087895-1|AAP97194.1| 375|Homo sapiens G-16 protein. 87 4e-16
EF011621-1|ABK41111.1| 357|Homo sapiens CDW11/WDR57 protein. 87 6e-16
BC001494-1|AAH01494.1| 357|Homo sapiens WD repeat domain 57 (U5... 87 6e-16
AL451070-1|CAH71848.1| 357|Homo sapiens WD repeat domain 57 (U5... 87 6e-16
AF083383-1|AAC64084.1| 310|Homo sapiens 38kDa splicing factor p... 87 6e-16
U82756-1|AAC02261.1| 520|Homo sapiens WD splicing factor Hprp4p... 86 8e-16
BC024267-1|AAH24267.1| 594|Homo sapiens TRAF7 protein protein. 85 1e-15
AY569455-1|AAS68363.1| 670|Homo sapiens TRAF7 protein. 85 1e-15
AF001687-1|AAB87640.1| 521|Homo sapiens U4/U6 snRNP 60 kDa prot... 85 2e-15
BC119693-1|AAI19694.1| 441|Homo sapiens WDR51A protein protein. 85 2e-15
BC119692-1|AAI19693.1| 407|Homo sapiens WD repeat domain 51A pr... 85 2e-15
BC110877-1|AAI10878.1| 359|Homo sapiens WDR51A protein protein. 85 2e-15
AK075289-1|BAC11525.1| 407|Homo sapiens protein ( Homo sapiens ... 85 2e-15
AL121990-7|CAI22015.1| 589|Homo sapiens TAF5-like RNA polymeras... 84 3e-15
AJ009770-1|CAA08816.1| 260|Homo sapiens putative transcription ... 84 3e-15
AF069736-1|AAC39906.1| 589|Homo sapiens PCAF associated factor ... 84 3e-15
BC007417-1|AAH07417.2| 396|Homo sapiens WDR51A protein protein. 83 5e-15
AK222501-1|BAD96221.1| 392|Homo sapiens hypothetical protein FL... 83 7e-15
AK093017-1|BAC04021.1| 619|Homo sapiens protein ( Homo sapiens ... 83 9e-15
BC036713-1|AAH36713.1| 542|Homo sapiens ATG16L2 protein protein. 82 2e-14
AK127882-1|BAC87175.1| 369|Homo sapiens protein ( Homo sapiens ... 82 2e-14
X95525-1|CAA64777.1| 799|Homo sapiens hTAFII100 protein. 81 3e-14
U80191-1|AAC51215.1| 800|Homo sapiens TFIID subunit TAFII100 pr... 81 3e-14
U75309-1|AAC50902.1| 801|Homo sapiens TBP-associated factor pro... 81 3e-14
BC052268-1|AAH52268.2| 800|Homo sapiens TAF5 RNA polymerase II,... 81 3e-14
AL591408-4|CAI16747.1| 800|Homo sapiens TAF5 RNA polymerase II,... 81 3e-14
AK223615-1|BAD97335.1| 803|Homo sapiens Transcription initiatio... 81 3e-14
AK090597-1|BAC03485.1| 513|Homo sapiens protein ( Homo sapiens ... 81 3e-14
M36429-1|AAA63264.1| 340|Homo sapiens protein ( Human transduci... 81 4e-14
M16514-1|AAA03179.1| 340|Homo sapiens GNB2 protein. 81 4e-14
CR541729-1|CAG46530.1| 340|Homo sapiens GNB2 protein. 81 4e-14
BC068003-1|AAH68003.1| 340|Homo sapiens guanine nucleotide bind... 81 4e-14
BC012348-1|AAH12348.1| 340|Homo sapiens guanine nucleotide bind... 81 4e-14
BC010073-1|AAH10073.1| 340|Homo sapiens guanine nucleotide bind... 81 4e-14
AF501883-1|AAM15919.1| 340|Homo sapiens guanine nucleotide bind... 81 4e-14
AF053356-4|AAC78794.1| 340|Homo sapiens GNB2 protein. 81 4e-14
U72342-1|AAC51111.1| 410|Homo sapiens platelet activating facto... 79 9e-14
L13386-1|AAA02881.1| 410|Homo sapiens Miller-Dieker lissencepha... 79 9e-14
L13385-1|AAA02880.1| 410|Homo sapiens Miller-Dieker lissencepha... 79 9e-14
EF011619-1|ABK41109.1| 478|Homo sapiens CDW9/WDR51B protein. 79 9e-14
BC064638-1|AAH64638.1| 410|Homo sapiens platelet-activating fac... 79 9e-14
BC026080-1|AAH26080.1| 478|Homo sapiens WD repeat domain 51B pr... 79 9e-14
AK074772-1|BAC11198.1| 478|Homo sapiens protein ( Homo sapiens ... 79 9e-14
AF400434-1|AAK92483.1| 410|Homo sapiens platelet-activating fac... 79 9e-14
AF208837-1|AAL34972.1| 410|Homo sapiens Miller-Dieker lissencep... 79 9e-14
M16538-1|AAA35922.1| 340|Homo sapiens protein ( Human signal-tr... 79 2e-13
AJ243003-1|CAB55579.1| 1205|Homo sapiens apoptotic protease acti... 79 2e-13
BC000873-1|AAH00873.1| 340|Homo sapiens guanine nucleotide bind... 78 2e-13
AF300648-1|AAG18442.1| 340|Homo sapiens guanine nucleotide bind... 78 2e-13
AB209173-1|BAD92410.1| 832|Homo sapiens transducin beta-like 3 ... 78 2e-13
CR456762-1|CAG33043.1| 655|Homo sapiens KATNB1 protein. 78 3e-13
BT007022-1|AAP35668.1| 655|Homo sapiens katanin p80 (WD40-conta... 78 3e-13
BC001353-1|AAH01353.1| 655|Homo sapiens katanin p80 (WD repeat ... 78 3e-13
X04526-2|CAA28207.1| 340|Homo sapiens protein ( Human liver mRN... 77 4e-13
M36430-1|AAA63265.1| 247|Homo sapiens protein ( Human transduci... 77 4e-13
L13387-1|AAA02882.1| 288|Homo sapiens Miller-Dieker lissencepha... 77 4e-13
CR456784-1|CAG33065.1| 340|Homo sapiens GNB1 protein. 77 4e-13
BT007305-1|AAP35969.1| 340|Homo sapiens guanine nucleotide bind... 77 4e-13
BC008991-1|AAH08991.1| 340|Homo sapiens guanine nucleotide bind... 77 4e-13
BC005888-1|AAH05888.1| 340|Homo sapiens guanine nucleotide bind... 77 4e-13
BC004186-1|AAH04186.1| 340|Homo sapiens guanine nucleotide bind... 77 4e-13
AL109917-5|CAI95654.1| 340|Homo sapiens guanine nucleotide bind... 77 4e-13
AL031282-2|CAI20029.1| 340|Homo sapiens guanine nucleotide bind... 77 4e-13
AJ243010-1|CAB55586.1| 1205|Homo sapiens apoptotic protease acti... 77 4e-13
AF501882-1|AAM15918.1| 340|Homo sapiens guanine nucleotide bind... 77 4e-13
BC035409-1|AAH35409.1| 808|Homo sapiens transducin (beta)-like ... 77 5e-13
BC014007-1|AAH14007.1| 808|Homo sapiens TBL3 protein protein. 77 5e-13
BC010231-1|AAH10231.1| 808|Homo sapiens transducin (beta)-like ... 77 5e-13
AJ243008-1|CAB55584.1| 1205|Homo sapiens apoptotic protease acti... 77 5e-13
AJ243007-1|CAB55583.1| 1205|Homo sapiens apoptotic protease acti... 77 5e-13
AJ243004-1|CAB55580.1| 1205|Homo sapiens apoptotic protease acti... 77 5e-13
AF013263-1|AAC51678.1| 1194|Homo sapiens apoptotic protease acti... 77 5e-13
AF070603-1|AAC28655.1| 207|Homo sapiens beta-subunit signal tra... 77 6e-13
CR457333-1|CAG33614.1| 305|Homo sapiens REC14 protein. 76 8e-13
AJ243107-1|CAB56462.1| 1171|Homo sapiens apoptotic protease acti... 76 8e-13
AJ243011-1|CAB55587.1| 1205|Homo sapiens protease activating fac... 76 8e-13
AJ243006-1|CAB55582.1| 1205|Homo sapiens apoptotic protease acti... 76 8e-13
BC047921-1|AAH47921.1| 563|Homo sapiens WDR86 protein protein. 76 1e-12
AJ243005-1|CAB55581.1| 1205|Homo sapiens apoptotic protease acti... 75 1e-12
AF208838-1|AAL34973.1| 410|Homo sapiens Miller-Dieker lissencep... 75 2e-12
U02609-1|AAA18945.1| 519|Homo sapiens transducin-like protein p... 75 2e-12
BC010080-1|AAH10080.1| 305|Homo sapiens WD repeat domain 61 pro... 75 2e-12
AK024754-1|BAB14986.1| 305|Homo sapiens protein ( Homo sapiens ... 75 2e-12
AF309553-1|AAG31639.1| 305|Homo sapiens meiotic recombination p... 75 2e-12
AF100786-1|AAP97225.1| 305|Homo sapiens G protein beta subunit-... 75 2e-12
EF011613-1|ABK41103.1| 513|Homo sapiens CDW3/SMU1 protein. 74 4e-12
BC110654-1|AAI10655.1| 513|Homo sapiens smu-1 suppressor of mec... 74 4e-12
BC021905-1|AAH21905.1| 896|Homo sapiens Unknown (protein for IM... 74 4e-12
BC002876-1|AAH02876.1| 513|Homo sapiens smu-1 suppressor of mec... 74 4e-12
AL450327-2|CAH70884.1| 1821|Homo sapiens protein ( Human DNA seq... 74 4e-12
AL356776-2|CAI14406.1| 1821|Homo sapiens protein ( Human DNA seq... 74 4e-12
AL162590-6|CAI15554.1| 513|Homo sapiens smu-1 suppressor of mec... 74 4e-12
AK057039-1|BAB71353.1| 912|Homo sapiens protein ( Homo sapiens ... 74 4e-12
AK001667-1|BAA91822.1| 513|Homo sapiens protein ( Homo sapiens ... 74 4e-12
AJ303102-1|CAC83118.1| 1821|Homo sapiens WD repeat domain 11 pro... 74 4e-12
AF052432-1|AAC09328.1| 655|Homo sapiens katanin p80 subunit pro... 73 6e-12
M24194-1|AAA59626.1| 317|Homo sapiens MHC B complex protein 12.... 73 1e-11
CR541909-1|CAG46707.1| 317|Homo sapiens GNB2L1 protein. 73 1e-11
CR456978-1|CAG33259.1| 317|Homo sapiens GNB2L1 protein. 73 1e-11
BC032006-1|AAH32006.1| 317|Homo sapiens guanine nucleotide bind... 73 1e-11
BC021993-1|AAH21993.1| 317|Homo sapiens guanine nucleotide bind... 73 1e-11
BC019362-1|AAH19362.1| 317|Homo sapiens guanine nucleotide bind... 73 1e-11
BC019093-1|AAH19093.1| 317|Homo sapiens guanine nucleotide bind... 73 1e-11
BC017287-1|AAH17287.1| 317|Homo sapiens guanine nucleotide bind... 73 1e-11
BC014788-1|AAH14788.1| 317|Homo sapiens guanine nucleotide bind... 73 1e-11
BC014256-1|AAH14256.1| 317|Homo sapiens guanine nucleotide bind... 73 1e-11
BC010119-1|AAH10119.1| 317|Homo sapiens guanine nucleotide bind... 73 1e-11
BC000366-1|AAH00366.1| 317|Homo sapiens guanine nucleotide bind... 73 1e-11
BC000214-1|AAH00214.1| 317|Homo sapiens guanine nucleotide bind... 73 1e-11
AY159316-1|AAO21313.1| 347|Homo sapiens lung cancer oncogene 7 ... 73 1e-11
AK222488-1|BAD96208.1| 317|Homo sapiens guanine nucleotide bind... 72 1e-11
BC107125-1|AAI07126.1| 248|Homo sapiens WDR86 protein protein. 71 2e-11
AL121993-4|CAI22739.1| 943|Homo sapiens WD repeat domain 3 prot... 71 4e-11
AF083217-1|AAD45865.1| 943|Homo sapiens WD repeat protein WDR3 ... 71 4e-11
BC023662-1|AAH23662.2| 475|Homo sapiens RRP9, small subunit (SS... 70 5e-11
BC010048-1|AAH10048.1| 475|Homo sapiens RRP9, small subunit (SS... 70 5e-11
BC009879-1|AAH09879.1| 475|Homo sapiens RRP9, small subunit (SS... 70 5e-11
BC001113-1|AAH01113.1| 475|Homo sapiens RRP9, small subunit (SS... 70 5e-11
AJ001340-1|CAA04687.1| 475|Homo sapiens U3 snoRNP associated 55... 70 5e-11
M95627-1|AAA68889.1| 452|Homo sapiens angio-associated migrator... 70 7e-11
CR456755-1|CAG33036.1| 452|Homo sapiens AAMP protein. 70 7e-11
BC039866-1|AAH39866.2| 434|Homo sapiens angio-associated, migra... 70 7e-11
BC020244-1|AAH20244.1| 429|Homo sapiens Similar to angio-associ... 70 7e-11
BC018698-1|AAH18698.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 70 7e-11
BC018665-1|AAH18665.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 70 7e-11
BC008719-1|AAH08719.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 70 7e-11
AJ131186-1|CAB51857.1| 504|Homo sapiens nuclear matrix protein ... 70 7e-11
BC015920-1|AAH15920.1| 297|Homo sapiens GNB3 protein protein. 69 9e-11
AJ243048-1|CAB55588.1| 1248|Homo sapiens apoptotic protease acti... 69 9e-11
AF149794-1|AAD34016.1| 1248|Homo sapiens apoptotic protease acti... 69 9e-11
AF134397-1|AAD38344.1| 1237|Homo sapiens apoptotic protease acti... 69 9e-11
AB007873-1|BAA24843.2| 1237|Homo sapiens KIAA0413 protein. 69 9e-11
BC025392-1|AAH25392.1| 620|Homo sapiens WD repeat domain 16 pro... 69 1e-10
AL031282-15|CAI20051.1| 197|Homo sapiens guanine nucleotide bin... 69 1e-10
AK094847-1|BAC04435.1| 630|Homo sapiens protein ( Homo sapiens ... 69 1e-10
AK074435-1|BAB85083.1| 412|Homo sapiens protein ( Homo sapiens ... 69 1e-10
AB065281-1|BAB83743.1| 620|Homo sapiens WDR16 protein. 69 1e-10
AJ243009-1|CAB55585.1| 1248|Homo sapiens apoptotic protease acti... 69 2e-10
AK223195-1|BAD96915.1| 315|Homo sapiens mitogen-activated prote... 67 4e-10
AK074217-1|BAB85020.1| 506|Homo sapiens protein ( Homo sapiens ... 67 4e-10
BC005870-1|AAH05870.1| 315|Homo sapiens mitogen-activated prote... 66 7e-10
BT009800-1|AAP88802.1| 340|Homo sapiens guanine nucleotide bind... 66 9e-10
BC002454-1|AAH02454.1| 340|Homo sapiens guanine nucleotide bind... 66 9e-10
BC000115-1|AAH00115.1| 340|Homo sapiens guanine nucleotide bind... 66 9e-10
Y12050-1|CAA72779.1| 340|Homo sapiens guanine nucleotide-bindin... 66 1e-09
U47924-5|AAB51313.1| 340|Homo sapiens G-protein beta-3 chain pr... 66 1e-09
M31328-1|AAA52582.1| 340|Homo sapiens GNB3 protein. 66 1e-09
BC114618-1|AAI14619.1| 332|Homo sapiens GNB1 protein protein. 66 1e-09
AY631872-1|AAT38116.1| 340|Homo sapiens guanine nucleotide bind... 66 1e-09
AY336089-1|AAR24619.1| 271|Homo sapiens proliferation-inducing ... 66 1e-09
AK131444-1|BAD18589.1| 472|Homo sapiens protein ( Homo sapiens ... 66 1e-09
AF501884-1|AAM15920.1| 340|Homo sapiens guanine nucleotide bind... 66 1e-09
AB209283-1|BAD92520.1| 327|Homo sapiens guanine nucleotide-bind... 66 1e-09
BC111490-1|AAI11491.1| 768|Homo sapiens BRWD3 protein protein. 65 2e-09
BC031227-1|AAH31227.2| 452|Homo sapiens WDR88 protein protein. 65 2e-09
BC014988-1|AAH14988.1| 919|Homo sapiens PWP2 periodic tryptopha... 65 2e-09
BC013309-1|AAH13309.1| 919|Homo sapiens PWP2 periodic tryptopha... 65 2e-09
AY497047-1|AAS45472.1| 1631|Homo sapiens bromodomain and WD repe... 65 2e-09
AY497046-1|AAS45471.1| 1802|Homo sapiens bromodomain and WD repe... 65 2e-09
AL669934-1|CAI95405.1| 1802|Homo sapiens bromodomain and WD repe... 65 2e-09
AL590031-1|CAI39936.2| 1802|Homo sapiens bromodomain and WD repe... 65 2e-09
AL512504-2|CAI95143.1| 1802|Homo sapiens bromodomain and WD repe... 65 2e-09
AK027854-1|BAB55412.1| 504|Homo sapiens protein ( Homo sapiens ... 65 2e-09
EF079890-1|ABN48555.1| 444|Homo sapiens ATG16 autophagy related... 65 2e-09
EF079889-1|ABN48554.1| 588|Homo sapiens ATG16 autophagy related... 65 2e-09
BC117337-1|AAI17338.1| 523|Homo sapiens ATG16L1 protein protein. 65 2e-09
BC071846-1|AAH71846.1| 475|Homo sapiens ATG16L1 protein protein. 65 2e-09
AY398617-1|AAR32130.1| 607|Homo sapiens APG16L beta protein. 65 2e-09
AK123876-1|BAC85713.1| 428|Homo sapiens protein ( Homo sapiens ... 65 2e-09
AC013726-3|AAY14860.1| 523|Homo sapiens unknown protein. 65 2e-09
X95263-1|CAA64560.1| 919|Homo sapiens PWP2 protein. 64 5e-09
U86136-1|AAC51107.1| 2627|Homo sapiens telomerase-associated pro... 64 5e-09
U56089-1|AAC50905.1| 919|Homo sapiens periodic tryptophan prote... 64 5e-09
U56085-1|AAC50904.1| 919|Homo sapiens periodic tryptophan prote... 64 5e-09
U53346-1|AAB08084.1| 919|Homo sapiens PWP2H protein protein. 64 5e-09
BC126107-1|AAI26108.1| 2627|Homo sapiens telomerase-associated p... 64 5e-09
AY729024-1|AAU43731.1| 1052|Homo sapiens ubiquitin ligase specif... 64 5e-09
AP001753-1|BAA95553.1| 919|Homo sapiens periodic tryptophan pro... 64 5e-09
AF127799-1|AAP97249.1| 305|Homo sapiens G protein beta subunit-... 64 5e-09
AB209669-1|BAD92906.1| 1903|Homo sapiens Telomerase protein comp... 64 5e-09
AB001517-2|BAA21137.1| 919|Homo sapiens PWP2 protein protein. 64 5e-09
BC028364-1|AAH28364.1| 1061|Homo sapiens FBXW10 protein protein. 63 6e-09
X70476-1|CAA49900.1| 906|Homo sapiens subunit of coatomer compl... 63 8e-09
BC001648-1|AAH01648.1| 432|Homo sapiens WD repeat domain 18 pro... 63 8e-09
BC000326-1|AAH00326.1| 906|Homo sapiens coatomer protein comple... 63 8e-09
BC000040-1|AAH00040.2| 432|Homo sapiens WD repeat domain 18 pro... 63 8e-09
BC015887-1|AAH15887.1| 404|Homo sapiens WD repeat and SOCS box-... 62 1e-08
AF229181-1|AAF71302.1| 404|Homo sapiens CS box-containing WD pr... 62 1e-08
AF163324-1|AAF80478.1| 404|Homo sapiens WSB-2 protein. 62 1e-08
BC013997-1|AAH13997.1| 353|Homo sapiens guanine nucleotide bind... 62 1e-08
AF501885-1|AAM15921.1| 353|Homo sapiens guanine nucleotide bind... 62 1e-08
AF300650-1|AAG18444.1| 395|Homo sapiens guanine nucleotide bind... 62 1e-08
AF017656-1|AAC63826.1| 353|Homo sapiens G protein beta 5 subuni... 62 1e-08
BC007620-1|AAH07620.1| 570|Homo sapiens TBL3 protein protein. 62 2e-08
AC004528-1|AAC12679.1| 431|Homo sapiens R32184_1 protein. 62 2e-08
Y12781-1|CAA73319.1| 577|Homo sapiens transducin (beta) like 1 ... 61 2e-08
BX640760-1|CAE45866.1| 1569|Homo sapiens hypothetical protein pr... 61 2e-08
BC052304-1|AAH52304.1| 577|Homo sapiens transducin (beta)-like ... 61 2e-08
BC032708-1|AAH32708.1| 526|Homo sapiens TBL1X protein protein. 61 2e-08
AL390071-3|CAI17183.1| 524|Homo sapiens neurobeachin protein. 61 2e-08
AL390071-2|CAI17182.1| 2943|Homo sapiens neurobeachin protein. 61 2e-08
AL357083-2|CAI15737.1| 2943|Homo sapiens neurobeachin protein. 61 2e-08
AL356430-2|CAH74071.1| 2943|Homo sapiens neurobeachin protein. 61 2e-08
AL163279-2|CAB90452.1| 2295|Homo sapiens homolog to cAMP respons... 61 2e-08
AL161902-1|CAI16334.1| 2943|Homo sapiens neurobeachin protein. 61 2e-08
AL161718-1|CAH72182.1| 2943|Homo sapiens neurobeachin protein. 61 2e-08
AL139083-2|CAH71883.1| 524|Homo sapiens neurobeachin protein. 61 2e-08
AL139083-1|CAH71882.1| 2943|Homo sapiens neurobeachin protein. 61 2e-08
AL138690-1|CAH72296.1| 2943|Homo sapiens neurobeachin protein. 61 2e-08
AJ292466-1|CAC44372.1| 2269|Homo sapiens WDR9 protein, form B p... 61 2e-08
AJ292465-1|CAC44371.1| 2320|Homo sapiens WDR9 protein, form A pr... 61 2e-08
AJ238214-1|CAC37033.2| 2269|Homo sapiens hypothetical protein pr... 61 2e-08
AF467288-1|AAM53531.1| 2946|Homo sapiens BCL8B protein protein. 61 2e-08
AB209608-1|BAD92845.1| 540|Homo sapiens transducin beta-like 1X... 61 2e-08
AB080587-1|BAD74072.1| 2199|Homo sapiens WD repeat protein WDR9-... 61 2e-08
AB080586-1|BAD74071.1| 2269|Homo sapiens WD repeat protein protein. 61 2e-08
AB046764-1|BAB13370.1| 1028|Homo sapiens KIAA1544 protein protein. 61 2e-08
BC010907-1|AAH10907.1| 392|Homo sapiens PAK1 interacting protei... 61 3e-08
AL358777-6|CAI14002.1| 392|Homo sapiens RP11-421M1.5 protein. 61 3e-08
AK131383-1|BAD18534.1| 141|Homo sapiens protein ( Homo sapiens ... 61 3e-08
AK000631-1|BAA91296.1| 391|Homo sapiens protein ( Homo sapiens ... 61 3e-08
AF072371-1|AAD41633.1| 472|Homo sapiens lysosomal trafficking r... 61 3e-08
CR456496-1|CAG30382.1| 327|Homo sapiens GNB1L protein. 60 4e-08
BC012060-1|AAH12060.1| 327|Homo sapiens guanine nucleotide bind... 60 4e-08
BC008809-1|AAH08809.2| 302|Homo sapiens AAMP protein protein. 60 4e-08
AF301895-1|AAG53933.1| 327|Homo sapiens WDVCF protein. 60 4e-08
AB051432-1|BAB33315.1| 386|Homo sapiens KIAA1645 protein protein. 60 4e-08
AB049212-1|BAB68408.1| 327|Homo sapiens G-protein beta subunit ... 60 4e-08
BC114493-1|AAI14494.1| 1514|Homo sapiens MAPKBP1 protein protein. 60 6e-08
BC113983-1|AAI13984.1| 1231|Homo sapiens MAPKBP1 protein protein. 60 6e-08
AB209899-1|BAD93136.1| 967|Homo sapiens Hypothetical protein DK... 60 6e-08
AB209438-1|BAD92675.1| 316|Homo sapiens PWP2 periodic tryptopha... 60 6e-08
AB177850-1|BAD66828.1| 1217|Homo sapiens KIAA0596 splice variant... 60 6e-08
AB011168-1|BAA25522.2| 1531|Homo sapiens KIAA0596 protein protein. 60 6e-08
M83822-1|AAB09603.1| 1918|Homo sapiens beige-like protein protein. 60 8e-08
BC126114-1|AAI26115.1| 579|Homo sapiens cell division cycle 40 ... 60 8e-08
BC117145-1|AAI17146.1| 579|Homo sapiens cell division cycle 40 ... 60 8e-08
AL671518-2|CAI13322.1| 579|Homo sapiens cell division cycle 40 ... 60 8e-08
AK222721-1|BAD96441.1| 579|Homo sapiens pre-mRNA splicing facto... 60 8e-08
AF467287-1|AAM53530.1| 2851|Homo sapiens beige-like protein prot... 60 8e-08
AF217149-1|AAG48559.1| 337|Homo sapiens beige-like protein prot... 60 8e-08
AF216648-1|AAG48558.2| 2863|Homo sapiens LPS responsive and Beig... 60 8e-08
AF061241-1|AAC25166.1| 542|Homo sapiens splicing factor hPRP17 ... 60 8e-08
AF038392-1|AAC39730.1| 579|Homo sapiens pre-mRNA splicing facto... 60 8e-08
AB208838-1|BAD92075.1| 1504|Homo sapiens Beige-like protein vari... 60 8e-08
X96586-1|CAA65405.1| 917|Homo sapiens FAN protein protein. 59 1e-07
BC113421-1|AAI13422.1| 514|Homo sapiens transducin (beta)-like ... 59 1e-07
BC021110-1|AAH21110.1| 421|Homo sapiens WD repeat and SOCS box-... 59 1e-07
AK222576-1|BAD96296.1| 421|Homo sapiens WD SOCS-box protein 1 i... 59 1e-07
AK074917-1|BAC11291.1| 421|Homo sapiens protein ( Homo sapiens ... 59 1e-07
AK022956-1|BAB14331.1| 514|Homo sapiens protein ( Homo sapiens ... 59 1e-07
AF314544-1|AAK00301.1| 514|Homo sapiens nuclear receptor co-rep... 59 1e-07
AF112205-1|AAF17193.1| 421|Homo sapiens WSB-1 protein protein. 59 1e-07
AF072880-1|AAD28808.1| 421|Homo sapiens SOCS box-containing WD ... 59 1e-07
AF069313-1|AAD20954.2| 421|Homo sapiens WSB1 protein protein. 59 1e-07
BC032551-1|AAH32551.1| 795|Homo sapiens phospholipase A2-activa... 58 2e-07
BC012352-1|AAH12352.1| 366|Homo sapiens WDR31 protein protein. 58 2e-07
AL449305-1|CAI10961.1| 367|Homo sapiens WD repeat domain 31 pro... 58 2e-07
AL137066-1|CAH70096.1| 367|Homo sapiens WD repeat domain 31 pro... 58 2e-07
AK093240-1|BAC04106.1| 367|Homo sapiens protein ( Homo sapiens ... 58 2e-07
AK002143-1|BAA92105.1| 544|Homo sapiens protein ( Homo sapiens ... 58 2e-07
U24105-1|AAB70879.1| 1224|Homo sapiens coatomer protein protein. 58 3e-07
BC038447-1|AAH38447.1| 1233|Homo sapiens COPA protein protein. 58 3e-07
AF283303-1|AAK57477.1| 392|Homo sapiens PAK/PLC-interacting pro... 58 3e-07
BC130473-1|AAI30474.1| 522|Homo sapiens transducin (beta)-like ... 57 4e-07
BC130471-1|AAI30472.1| 522|Homo sapiens transducin (beta)-like ... 57 4e-07
AK074434-1|BAB85082.1| 293|Homo sapiens protein ( Homo sapiens ... 57 4e-07
AF332222-1|AAK13474.1| 522|Homo sapiens transducin beta-like 1 ... 57 4e-07
AF332221-1|AAK13473.1| 522|Homo sapiens transducin beta-like 1 ... 57 4e-07
AF332220-1|AAK13472.1| 522|Homo sapiens transducin beta-like 1 ... 57 4e-07
BC065934-1|AAH65934.1| 410|Homo sapiens WD repeat and FYVE doma... 57 5e-07
BC041124-1|AAH41124.1| 917|Homo sapiens neutral sphingomyelinas... 57 5e-07
BC040525-1|AAH40525.1| 410|Homo sapiens WD repeat and FYVE doma... 57 5e-07
AK023415-1|BAB14569.1| 367|Homo sapiens protein ( Homo sapiens ... 57 5e-07
AK022888-1|BAB14294.1| 410|Homo sapiens protein ( Homo sapiens ... 57 5e-07
AJ310568-1|CAC83947.1| 410|Homo sapiens phosphoinositide-bindin... 57 5e-07
AF411977-1|AAL04161.1| 410|Homo sapiens WD40- and FYVE-domain c... 57 5e-07
AF268193-1|AAG44736.1| 514|Homo sapiens IRA1 protein. 57 5e-07
AC073641-1|AAY14924.1| 410|Homo sapiens unknown protein. 57 5e-07
AB037856-1|BAA92673.1| 415|Homo sapiens KIAA1435 protein protein. 57 5e-07
AB007918-1|BAA32294.2| 1628|Homo sapiens KIAA0449 protein protein. 56 7e-07
AB209201-1|BAD92438.1| 466|Homo sapiens WD repeat-containing pr... 56 9e-07
AB053276-1|BAB69430.1| 348|Homo sapiens TUWD12 protein. 56 9e-07
AB053266-1|BAB69057.1| 348|Homo sapiens TUWD12 protein. 56 9e-07
AL671518-1|CAI13321.1| 539|Homo sapiens cell division cycle 40 ... 56 1e-06
AL445068-1|CAI22519.1| 539|Homo sapiens cell division cycle 40 ... 56 1e-06
AB208903-1|BAD92140.1| 501|Homo sapiens pre-mRNA splicing facto... 56 1e-06
AK093494-1|BAC04184.1| 476|Homo sapiens protein ( Homo sapiens ... 55 2e-06
BC117698-1|AAI17699.1| 1358|Homo sapiens NWD1 protein protein. 55 2e-06
M99438-1|AAA61194.1| 772|Homo sapiens transducin-like enhancer ... 54 3e-06
M99435-1|AAA61192.1| 770|Homo sapiens transducin-like enhancer ... 54 3e-06
BC016946-1|AAH16946.1| 342|Homo sapiens WD repeat domain 77 pro... 54 3e-06
BC015747-1|AAH15747.1| 770|Homo sapiens transducin-like enhance... 54 3e-06
BC011778-1|AAH11778.1| 342|Homo sapiens WD repeat domain 77 pro... 54 3e-06
BC010100-1|AAH10100.1| 770|Homo sapiens transducin-like enhance... 54 3e-06
BC009411-1|AAH09411.1| 330|Homo sapiens WDR77 protein protein. 54 3e-06
BC006477-1|AAH06477.1| 342|Homo sapiens WD repeat domain 77 pro... 54 3e-06
BC001679-1|AAH01679.1| 342|Homo sapiens WD repeat domain 77 pro... 54 3e-06
AY225316-1|AAP79114.1| 342|Homo sapiens androgen receptor cofac... 54 3e-06
AM177180-1|CAJ45484.1| 1670|Homo sapiens kinesin-like protein KI... 54 3e-06
AL390195-6|CAC36041.1| 342|Homo sapiens MEP50 protein (MEP50) p... 54 3e-06
AL390195-5|CAI15627.1| 290|Homo sapiens MEP50 protein (MEP50) p... 54 3e-06
AL365190-2|CAI14977.1| 770|Homo sapiens transducin-like enhance... 54 3e-06
AL353682-1|CAI12595.1| 770|Homo sapiens transducin-like enhance... 54 3e-06
AK223189-1|BAD96909.1| 342|Homo sapiens methylosome protein 50 ... 54 3e-06
AF478464-1|AAL79917.1| 342|Homo sapiens MEP50 protein protein. 54 3e-06
AF106683-1|AAD43036.1| 421|Homo sapiens WSB-1 protein. 54 3e-06
AB073603-1|BAD38641.1| 342|Homo sapiens putative protein produc... 54 3e-06
BC025379-1|AAH25379.1| 571|Homo sapiens SPAG16 protein protein. 54 4e-06
AF492460-1|AAN64030.1| 1322|Homo sapiens WD repeat 17 protein. 54 4e-06
AF490390-1|AAM97147.1| 631|Homo sapiens sperm-associated WD rep... 54 4e-06
AF310672-1|AAM63956.1| 631|Homo sapiens PF20 variant 1a protein. 54 4e-06
BC047574-1|AAH47574.1| 899|Homo sapiens WDFY4 protein protein. 54 5e-06
BC043247-1|AAH43247.1| 767|Homo sapiens TLE3 protein protein. 54 5e-06
BC041831-1|AAH41831.1| 772|Homo sapiens TLE3 protein protein. 54 5e-06
BC034604-1|AAH34604.1| 753|Homo sapiens striatin, calmodulin bi... 54 5e-06
BC032420-1|AAH32420.1| 322|Homo sapiens WDFY4 protein protein. 54 5e-06
BC015694-1|AAH15694.2| 320|Homo sapiens WDFY4 protein protein. 54 5e-06
BC004910-1|AAH04910.2| 349|Homo sapiens STRN4 protein protein. 54 5e-06
AY583460-1|AAS90946.1| 767|Homo sapiens transducin-like enhance... 54 5e-06
AK074085-1|BAB84911.1| 1887|Homo sapiens FLJ00156 protein protein. 54 5e-06
AF212940-1|AAF29527.1| 753|Homo sapiens zinedin protein. 54 5e-06
AB209003-1|BAD92240.1| 755|Homo sapiens Zinedin variant protein. 54 5e-06
AB046827-1|BAB13433.1| 1270|Homo sapiens KIAA1607 protein protein. 54 5e-06
AB046767-1|BAB13373.1| 863|Homo sapiens KIAA1547 protein protein. 54 5e-06
M99439-1|AAA61195.1| 448|Homo sapiens transducin-like enhancer ... 53 9e-06
BC110334-1|AAI10335.1| 454|Homo sapiens F-box and WD repeat dom... 53 9e-06
BC060874-1|AAH60874.2| 973|Homo sapiens NBEAL2 protein protein. 53 9e-06
BC059405-1|AAH59405.2| 805|Homo sapiens TLE4 protein protein. 53 9e-06
BC045650-1|AAH45650.1| 704|Homo sapiens TLE4 protein protein. 53 9e-06
BC026353-1|AAH26353.1| 677|Homo sapiens WD repeat domain 48 pro... 53 9e-06
BC018738-1|AAH18738.1| 454|Homo sapiens F-box and WD repeat dom... 53 9e-06
AY358455-1|AAQ88820.1| 1003|Homo sapiens SQFE253 protein. 53 9e-06
AL445252-3|CAI13644.1| 764|Homo sapiens transducin-like enhance... 53 9e-06
AL358975-3|CAI13734.1| 764|Homo sapiens transducin-like enhance... 53 9e-06
AL353813-5|CAI41315.1| 764|Homo sapiens transducin-like enhance... 53 9e-06
AL161911-3|CAI95114.1| 208|Homo sapiens F-box and WD-40 domain ... 53 9e-06
AL161911-2|CAI95113.1| 454|Homo sapiens F-box and WD-40 domain ... 53 9e-06
AK131104-1|BAC85154.1| 2760|Homo sapiens FLJ00341 protein protein. 53 9e-06
AK125347-1|BAC86140.1| 277|Homo sapiens protein ( Homo sapiens ... 53 9e-06
AK022484-1|BAB14051.1| 454|Homo sapiens protein ( Homo sapiens ... 53 9e-06
AF468833-1|AAL78650.1| 677|Homo sapiens WD repeat endosomal pro... 53 9e-06
AF176698-1|AAF13226.1| 422|Homo sapiens F-box protein FBW2 prot... 53 9e-06
AF145024-1|AAP97276.1| 422|Homo sapiens MD6 protein protein. 53 9e-06
AF129531-1|AAF04465.1| 422|Homo sapiens F-box protein Fbw2 prot... 53 9e-06
AB040882-1|BAA95973.2| 680|Homo sapiens KIAA1449 protein protein. 53 9e-06
AB033087-1|BAA86575.1| 787|Homo sapiens KIAA1261 protein protein. 53 9e-06
AB011112-1|BAA25466.3| 2041|Homo sapiens KIAA0540 protein protein. 53 9e-06
AF242546-1|AAF60355.1| 423|Homo sapiens YTM1 protein. 52 1e-05
EF011617-1|ABK41107.1| 423|Homo sapiens CDW7/WDR12 protein. 52 2e-05
BC039254-1|AAH39254.1| 893|Homo sapiens WDR47 protein protein. 52 2e-05
BC036660-1|AAH36660.1| 1015|Homo sapiens MAPKBP1 protein protein. 52 2e-05
BC008082-1|AAH08082.1| 423|Homo sapiens WD repeat domain 12 pro... 52 2e-05
AL356133-3|CAH72641.1| 738|Homo sapiens phospholipase A2-activa... 52 2e-05
AK223544-1|BAD97264.1| 748|Homo sapiens Hypothetical protein DK... 52 2e-05
AK001743-1|BAA91875.1| 423|Homo sapiens protein ( Homo sapiens ... 52 2e-05
AJ238243-1|CAB42881.1| 738|Homo sapiens phospholipase A2 activa... 52 2e-05
AF145020-1|AAD42075.1| 649|Homo sapiens phospholipase A2 activa... 52 2e-05
AF083395-1|AAD03030.1| 738|Homo sapiens phospholipase A2-activa... 52 2e-05
AC010900-2|AAY24287.1| 423|Homo sapiens unknown protein. 52 2e-05
BC032685-1|AAH32685.1| 662|Homo sapiens Unknown (protein for IM... 52 2e-05
AK027402-1|BAB55088.1| 886|Homo sapiens protein ( Homo sapiens ... 51 3e-05
U65652-1|AAC52034.1| 252|Homo sapiens HREP protein protein. 51 4e-05
U43383-1|AAD10830.1| 196|Homo sapiens protein ( Human unidentif... 51 4e-05
AF045592-1|AAC69998.1| 252|Homo sapiens HREP protein protein. 51 4e-05
EF011612-1|ABK41102.1| 514|Homo sapiens CDW2/WDR26 protein. 50 6e-05
BX679664-5|CAH71327.1| 919|Homo sapiens WD repeat domain 47 pro... 50 6e-05
BX679664-4|CAH71326.1| 920|Homo sapiens WD repeat domain 47 pro... 50 6e-05
BX679664-3|CAH71325.1| 891|Homo sapiens WD repeat domain 47 pro... 50 6e-05
BC088354-1|AAH88354.1| 326|Homo sapiens G protein beta subunit-... 50 6e-05
BC065502-1|AAH65502.1| 778|Homo sapiens WDFY3 protein protein. 50 6e-05
BC063817-1|AAH63817.1| 404|Homo sapiens WDR26 protein protein. 50 6e-05
BC052301-1|AAH52301.2| 514|Homo sapiens WD repeat domain 26 pro... 50 6e-05
BC031471-1|AAH31471.2| 373|Homo sapiens WDR26 protein protein. 50 6e-05
BC015214-1|AAH15214.2| 437|Homo sapiens WDFY3 protein protein. 50 6e-05
AY304473-1|AAQ74770.1| 514|Homo sapiens WD40 repeat protein 26 ... 50 6e-05
AY221751-1|AAO67709.1| 498|Homo sapiens myocardial ischemic pre... 50 6e-05
AL449266-4|CAI14352.1| 891|Homo sapiens WD repeat domain 47 pro... 50 6e-05
AL449266-3|CAI14353.1| 919|Homo sapiens WD repeat domain 47 pro... 50 6e-05
AL449266-2|CAI14351.1| 920|Homo sapiens WD repeat domain 47 pro... 50 6e-05
AK055806-1|BAB71020.1| 722|Homo sapiens protein ( Homo sapiens ... 50 6e-05
AK024669-1|BAB14955.1| 367|Homo sapiens protein ( Homo sapiens ... 50 6e-05
AK022782-1|BAB14243.1| 423|Homo sapiens protein ( Homo sapiens ... 50 6e-05
AK022781-1|BAB14242.1| 423|Homo sapiens protein ( Homo sapiens ... 50 6e-05
AJ005257-1|CAA06444.1| 86|Homo sapiens protein ( Homo sapiens ... 50 6e-05
AF538685-1|AAN15137.1| 3526|Homo sapiens ALFY protein. 50 6e-05
AB209887-1|BAD93124.1| 725|Homo sapiens WD repeat domain 26 var... 50 6e-05
AB023210-1|BAA76837.2| 1556|Homo sapiens KIAA0993 protein protein. 50 6e-05
AB020700-1|BAA74916.2| 974|Homo sapiens KIAA0893 protein protein. 50 6e-05
D83782-1|BAA12111.2| 1283|Homo sapiens KIAA0199 protein. 50 8e-05
BC022967-1|AAH22967.1| 326|Homo sapiens WDR22 protein protein. 50 8e-05
BC020987-1|AAH20987.1| 905|Homo sapiens SCAP protein protein. 50 8e-05
AK075528-1|BAC11673.1| 379|Homo sapiens protein ( Homo sapiens ... 50 8e-05
AF080397-1|AAF20266.1| 493|Homo sapiens fizzy-related protein h... 50 8e-05
AC006011-2|AAX82033.1| 1336|Homo sapiens unknown protein. 50 8e-05
AB058727-1|BAB47453.1| 958|Homo sapiens KIAA1824 protein protein. 50 8e-05
AB044749-1|BAB32435.1| 1336|Homo sapiens WDC146 protein. 50 8e-05
BC117306-1|AAI17307.1| 698|Homo sapiens WD repeat domain 65 pro... 49 1e-04
BC117280-1|AAI17281.1| 698|Homo sapiens WD repeat domain 65 pro... 49 1e-04
BC052292-1|AAH52292.1| 326|Homo sapiens GBL protein protein. 49 1e-04
AL139138-2|CAI18963.1| 698|Homo sapiens WD repeat domain 65 pro... 49 1e-04
AK056562-1|BAB71217.1| 698|Homo sapiens protein ( Homo sapiens ... 49 1e-04
AK001642-1|BAA91803.1| 795|Homo sapiens protein ( Homo sapiens ... 49 1e-04
D26488-1|BAA05499.1| 686|Homo sapiens KIAA0007 protein. 49 1e-04
BC028387-1|AAH28387.1| 569|Homo sapiens WD repeat domain 20 pro... 49 1e-04
AY583459-1|AAS90945.1| 764|Homo sapiens transducin-like enhance... 49 1e-04
AF327354-1|AAL56014.1| 572|Homo sapiens DMR protein protein. 49 1e-04
AB209148-1|BAD92385.1| 439|Homo sapiens WD repeat domain 20 iso... 49 1e-04
BT020045-1|AAV38848.1| 350|Homo sapiens unr-interacting protein... 48 2e-04
BT020044-1|AAV38847.1| 350|Homo sapiens unr-interacting protein... 48 2e-04
BC062306-1|AAH62306.1| 350|Homo sapiens serine/threonine kinase... 48 2e-04
BC034964-1|AAH34964.1| 920|Homo sapiens WD repeat domain 47 pro... 48 2e-04
BC017364-1|AAH17364.1| 743|Homo sapiens transducin-like enhance... 48 2e-04
BC000162-1|AAH00162.1| 350|Homo sapiens serine/threonine kinase... 48 2e-04
AY172970-1|AAO45288.1| 974|Homo sapiens beach protein protein. 48 2e-04
AY049776-1|AAL15433.1| 350|Homo sapiens unr-interacting protein... 48 2e-04
AK128636-1|BAC87543.1| 1042|Homo sapiens protein ( Homo sapiens ... 48 2e-04
AJ010025-1|CAB38041.1| 350|Homo sapiens unr-interacting protein... 48 2e-04
AC007766-2|AAD38075.1| 553|Homo sapiens TLE2_HUMAN [AA 191- 743... 48 2e-04
AB024327-1|BAA75544.1| 350|Homo sapiens WD-40 repeat protein pr... 48 2e-04
X72841-1|CAA51360.1| 425|Homo sapiens IEF 7442 protein. 48 2e-04
U35143-1|AAC50231.1| 425|Homo sapiens retinoblastoma-binding pr... 48 2e-04
CR541701-1|CAG46502.1| 425|Homo sapiens RBBP7 protein. 48 2e-04
BC114501-1|AAI14502.1| 425|Homo sapiens retinoblastoma binding ... 48 2e-04
BC114500-1|AAI14501.1| 425|Homo sapiens retinoblastoma binding ... 48 2e-04
AY358182-1|AAQ88549.1| 470|Homo sapiens SSGL9393 protein. 48 2e-04
AL929302-6|CAI41284.1| 420|Homo sapiens retinoblastoma binding ... 48 2e-04
AL929302-5|CAI41283.1| 469|Homo sapiens retinoblastoma binding ... 48 2e-04
AK131467-1|BAD18612.1| 419|Homo sapiens protein ( Homo sapiens ... 48 2e-04
AK126622-1|BAC86616.1| 1060|Homo sapiens protein ( Homo sapiens ... 48 2e-04
BC014004-1|AAH14004.1| 400|Homo sapiens WD repeat and FYVE doma... 48 3e-04
AY099325-1|AAM33134.1| 1490|Homo sapiens rabconnectin-3 beta pro... 48 3e-04
AL139183-1|CAH73431.1| 400|Homo sapiens WD repeat and FYVE doma... 48 3e-04
AL136525-1|CAH70585.1| 400|Homo sapiens WD repeat and FYVE doma... 48 3e-04
AK058149-1|BAB71687.1| 297|Homo sapiens protein ( Homo sapiens ... 48 3e-04
AF188125-1|AAL03983.1| 1457|Homo sapiens TGF-beta resistance-ass... 48 3e-04
AB011113-1|BAA25467.2| 1500|Homo sapiens KIAA0541 protein protein. 48 3e-04
U05340-1|AAA19017.1| 499|Homo sapiens p55CDC protein. 47 4e-04
M99436-1|AAA61193.1| 743|Homo sapiens transducin-like enhancer ... 47 4e-04
>BC127949-1|AAI27950.1| 314|Homo sapiens similar to hypothetical
protein FLJ25955 protein.
Length = 314
Score = 107 bits (257), Expect = 3e-22
Identities = 79/271 (29%), Positives = 118/271 (43%), Gaps = 5/271 (1%)
Query: 975 SRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVV 1034
S DGQ+ +G G V W+ + +L L GH G + FSP+ L S S D TV +
Sbjct: 30 SPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASASCDCTVRL 89
Query: 1035 WQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSAS 1094
W +A KGH +++T+ D R+ S + V +W V SG +L G S
Sbjct: 90 WDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDS 149
Query: 1095 I---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVT 1151
I D + + D++VRIW L + ++ H+ I+C +A S + +
Sbjct: 150 IQSSDFSPTVNCLATGSWDSTVRIWDLRMVTPAVSHQALEGHSGNISCLCYSA-SGLLAS 208
Query: 1152 GSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXX 1211
GS D ++ +WK L L GH V +A S ++ + S + + VWD NT
Sbjct: 209 GSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFS-PDELWLASAGYSRMVKVWDCNTGKC 267
Query: 1212 XXXXXXXXXKVTCVKVTGDGTIAVSCAEDKT 1242
T DG I VS A D+T
Sbjct: 268 LETLKGVLDVAHTCAFTPDGKILVSGAADQT 298
Score = 77.4 bits (182), Expect = 4e-13
Identities = 60/254 (23%), Positives = 99/254 (38%), Gaps = 11/254 (4%)
Query: 1007 HIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAM 1066
H G + FSP+ ++L+GSED V W+ GH+ ++ DG
Sbjct: 20 HGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFA 79
Query: 1067 SSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDN 1123
S+ V +W V L G S++ V+ + L+ G D V +W + G
Sbjct: 80 SASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSG-- 137
Query: 1124 SEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKL---DGGKLSQVLVGHSDIVT 1180
+ R V H + I + + TGS D ++++W L Q L GHS ++
Sbjct: 138 -QMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWDLRMVTPAVSHQALEGHSGNIS 196
Query: 1181 CVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAED 1240
C+ S + + SGSWD + +W T V + + D S
Sbjct: 197 CLCYSASG--LLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYS 254
Query: 1241 KTLIIWETKRGLAL 1254
+ + +W+ G L
Sbjct: 255 RMVKVWDCNTGKCL 268
Score = 68.1 bits (159), Expect = 2e-10
Identities = 55/236 (23%), Positives = 93/236 (39%), Gaps = 9/236 (3%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
P+ S DG L AS VR+W ++ + L GH + V+FSP++ + SG
Sbjct: 65 PVKFCRFSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGG 124
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW---LVDSGIV 1084
D+ V++W + GH +IQ+ + V +W +V +
Sbjct: 125 WDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWDLRMVTPAVS 184
Query: 1085 LHSATGPSASIDVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ G S +I +L+ G D ++ IW S + H + A
Sbjct: 185 HQALEGHSGNISCLCYSASGLLASGSWDKTIHIWK---PTTSSLLIQLKGHVTWVKSIAF 241
Query: 1143 TADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWD 1198
+ D + + +KVW + GK + L G D+ A + K +VSG+ D
Sbjct: 242 SPDELWLASAGYSRMVKVWDCNTGKCLETLKGVLDVAHTCAFTPDGKI-LVSGAAD 296
Score = 57.6 bits (133), Expect = 3e-07
Identities = 54/242 (22%), Positives = 96/242 (39%), Gaps = 5/242 (2%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+P GQ L+ G W S + GH+G + + + + S D +V +
Sbjct: 30 SPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASASCDCTVRL 89
Query: 721 WDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
WD+ + H V V+ + + SGG D V++ + G ++ L HR S
Sbjct: 90 WDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDS 149
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVT----DDNVFLLT 836
+ S N TGS D TV W++ T + A + H +++ + L +
Sbjct: 150 IQSSDFSPTVNCLATGSWDSTVRIWDLRMVTPAVSHQA-LEGHSGNISCLCYSASGLLAS 208
Query: 837 LQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
D +H+ T + L LK H VK + D +A + + ++ ++ + L
Sbjct: 209 GSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKCL 268
Query: 897 RT 898
T
Sbjct: 269 ET 270
Score = 56.8 bits (131), Expect = 5e-07
Identities = 51/215 (23%), Positives = 87/215 (40%), Gaps = 5/215 (2%)
Query: 686 KVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAI 745
+V F H G + + + Q LLTGSED V W+ + + ++ H PV
Sbjct: 13 RVKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFS 72
Query: 746 VNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
+ L S D V + + + L H+ SV +V D +G D V W
Sbjct: 73 PDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLW 132
Query: 806 NVENFTLLSTVTA-GVPIHIFDVTDDNVFLLTLQGDNELHL--RTFITGTYLH-PLKRHK 861
+V++ +L + I D + L T D+ + + +T H L+ H
Sbjct: 133 DVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWDLRMVTPAVSHQALEGHS 192
Query: 862 AKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
+ C C + S +A G D+ I+++ ++ LL
Sbjct: 193 GNISCLCYS-ASGLLASGSWDKTIHIWKPTTSSLL 226
Score = 46.4 bits (105), Expect = 8e-04
Identities = 49/232 (21%), Positives = 92/232 (39%), Gaps = 5/232 (2%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
+ + +P G A +LW + + KGH S+ + + +S+ L +G D
Sbjct: 67 KFCRFSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWD 126
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL--VDGALVTK 773
V++WD+ + + ++ H + + + +G DS V I L V A+ +
Sbjct: 127 KRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWDLRMVTPAVSHQ 186
Query: 774 -LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP-IHIFDVTDDN 831
L+ H G+++ + G + +GS D T+ W +LL + V + + D
Sbjct: 187 ALEGHSGNISCLCYSASG-LLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDE 245
Query: 832 VFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQ 883
++L + + + TG L LK D + G ADQ
Sbjct: 246 LWLASAGYSRMVKVWDCNTGKCLETLKGVLDVAHTCAFTPDGKILVSGAADQ 297
Score = 45.6 bits (103), Expect = 0.001
Identities = 67/310 (21%), Positives = 125/310 (40%), Gaps = 22/310 (7%)
Query: 725 TLAVK-TKIL-EHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
TLAV+ K +H V A + ++++G +D V G L+ +L H G V
Sbjct: 8 TLAVRRVKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVK 67
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDN 841
+ DG++F + S D TV W+V L + + + D+ L + D
Sbjct: 68 FCRFSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDK 127
Query: 842 ELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXX 901
+ L +G L L H+ ++ + + +A G D + ++ L T
Sbjct: 128 RVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWDLRMV----TPAV 183
Query: 902 XXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQA 961
+A G + S + + ++PT Q K ++T +++
Sbjct: 184 SHQALEGHSGNISCLCYSASG---LLASGSWDKTIHIWKPTTSSLLIQLKG--HVTWVKS 238
Query: 962 EQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNL 1021
I S E+ L ++G +R +V+VW +T + TL G + F+P+
Sbjct: 239 -----IAFSPDEL----WLASAGYSR-MVKVWDCNTGKCLETLKGVLDVAHTCAFTPDGK 288
Query: 1022 LVLSGSEDRT 1031
+++SG+ D+T
Sbjct: 289 ILVSGAADQT 298
>AL354928-6|CAI39637.1| 314|Homo sapiens WD repeat domain 38 protein.
Length = 314
Score = 105 bits (253), Expect = 9e-22
Identities = 78/271 (28%), Positives = 117/271 (43%), Gaps = 5/271 (1%)
Query: 975 SRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVV 1034
S DGQ+ +G G V W+ + +L L GH G + FSP+ L S S D TV +
Sbjct: 30 SPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASASCDCTVRL 89
Query: 1035 WQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSAS 1094
W +A KGH +++T+ D R+ S + V +W V SG +L G S
Sbjct: 90 WDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDS 149
Query: 1095 I---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVT 1151
I D + + D++V IW L + ++ H+ I+C +A S + +
Sbjct: 150 IQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSA-SGLLAS 208
Query: 1152 GSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXX 1211
GS D ++ +WK L L GH V +A S ++ + S + + VWD NT
Sbjct: 209 GSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFS-PDELWLASAGYSRMVKVWDCNTGKC 267
Query: 1212 XXXXXXXXXKVTCVKVTGDGTIAVSCAEDKT 1242
T DG I VS A D+T
Sbjct: 268 LETLKGVLDVAHTCAFTPDGKILVSGAADQT 298
Score = 75.8 bits (178), Expect = 1e-12
Identities = 60/254 (23%), Positives = 98/254 (38%), Gaps = 11/254 (4%)
Query: 1007 HIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAM 1066
H G + FSP+ ++L+GSED V W+ GH+ ++ DG
Sbjct: 20 HGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFA 79
Query: 1067 SSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDN 1123
S+ V +W V L G S++ V+ + L+ G D V +W + G
Sbjct: 80 SASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSG-- 137
Query: 1124 SEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKL---DGGKLSQVLVGHSDIVT 1180
+ R V H + I + + TGS D ++ +W L Q L GHS ++
Sbjct: 138 -QMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANIS 196
Query: 1181 CVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAED 1240
C+ S + + SGSWD + +W T V + + D S
Sbjct: 197 CLCYSASG--LLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYS 254
Query: 1241 KTLIIWETKRGLAL 1254
+ + +W+ G L
Sbjct: 255 RMVKVWDCNTGKCL 268
Score = 72.9 bits (171), Expect = 8e-12
Identities = 57/236 (24%), Positives = 95/236 (40%), Gaps = 9/236 (3%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
P+ S DG L AS VR+W ++ + L GH + V+FSP++ + SG
Sbjct: 65 PVKFCRFSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGG 124
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW---LVDSGIV 1084
D+ V++W + GH +IQ+ + VH+W +V +
Sbjct: 125 WDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVS 184
Query: 1085 LHSATGPSASIDVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ G SA+I +L+ G D ++ IW S + H + A
Sbjct: 185 HQALEGHSANISCLCYSASGLLASGSWDKTIHIWK---PTTSSLLIQLKGHVTWVKSIAF 241
Query: 1143 TADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWD 1198
+ D + + +KVW + GK + L G D+ A + K +VSG+ D
Sbjct: 242 SPDELWLASAGYSRMVKVWDCNTGKCLETLKGVLDVAHTCAFTPDGKI-LVSGAAD 296
Score = 61.7 bits (143), Expect = 2e-08
Identities = 53/215 (24%), Positives = 89/215 (41%), Gaps = 5/215 (2%)
Query: 686 KVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAI 745
+V F H G + + + Q LLTGSED V W+ + + ++ H PV
Sbjct: 13 RVKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFS 72
Query: 746 VNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
+ L S D V + + + L H+ SV +V D +G D V W
Sbjct: 73 PDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLW 132
Query: 806 NVENFTLLSTVTA-GVPIHIFDVTDDNVFLLTLQGDNELHL--RTFITGTYLH-PLKRHK 861
+V++ +L + I D + L T D+ +H+ +T H L+ H
Sbjct: 133 DVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHS 192
Query: 862 AKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
A + C C + S +A G D+ I+++ ++ LL
Sbjct: 193 ANISCLCYS-ASGLLASGSWDKTIHIWKPTTSSLL 226
Score = 58.0 bits (134), Expect = 2e-07
Identities = 54/242 (22%), Positives = 96/242 (39%), Gaps = 5/242 (2%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+P GQ L+ G W S + GH+G + + + + S D +V +
Sbjct: 30 SPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASASCDCTVRL 89
Query: 721 WDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
WD+ + H V V+ + + SGG D V++ + G ++ L HR S
Sbjct: 90 WDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDS 149
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVT----DDNVFLLT 836
+ S N TGS D TV W++ T + A + H +++ + L +
Sbjct: 150 IQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQA-LEGHSANISCLCYSASGLLAS 208
Query: 837 LQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
D +H+ T + L LK H VK + D +A + + ++ ++ + L
Sbjct: 209 GSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKCL 268
Query: 897 RT 898
T
Sbjct: 269 ET 270
Score = 47.6 bits (108), Expect = 3e-04
Identities = 67/310 (21%), Positives = 126/310 (40%), Gaps = 22/310 (7%)
Query: 725 TLAVK-TKIL-EHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
TLAV+ K +H V A + ++++G +D V G L+ +L H G V
Sbjct: 8 TLAVRRVKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVK 67
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDN 841
+ DG++F + S D TV W+V L + + + D+ L + D
Sbjct: 68 FCRFSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDK 127
Query: 842 ELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXX 901
+ L +G L L H+ ++ + + +A G D ++++ L T
Sbjct: 128 RVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMV----TPAV 183
Query: 902 XXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQA 961
+A G + S + + ++PT Q K ++T +++
Sbjct: 184 SHQALEGHSANISCLCYSASG---LLASGSWDKTIHIWKPTTSSLLIQLKG--HVTWVKS 238
Query: 962 EQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNL 1021
I S E+ L ++G +R +V+VW +T + TL G + F+P+
Sbjct: 239 -----IAFSPDEL----WLASAGYSR-MVKVWDCNTGKCLETLKGVLDVAHTCAFTPDGK 288
Query: 1022 LVLSGSEDRT 1031
+++SG+ D+T
Sbjct: 289 ILVSGAADQT 298
Score = 44.0 bits (99), Expect = 0.004
Identities = 48/232 (20%), Positives = 91/232 (39%), Gaps = 5/232 (2%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
+ + +P G A +LW + + KGH S+ + + +S+ L +G D
Sbjct: 67 KFCRFSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWD 126
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL--VDGALVTK 773
V++WD+ + + ++ H + + + +G DS V I L V A+ +
Sbjct: 127 KRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQ 186
Query: 774 -LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP-IHIFDVTDDN 831
L+ H +++ + G + +GS D T+ W +LL + V + + D
Sbjct: 187 ALEGHSANISCLCYSASG-LLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDE 245
Query: 832 VFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQ 883
++L + + + TG L LK D + G ADQ
Sbjct: 246 LWLASAGYSRMVKVWDCNTGKCLETLKGVLDVAHTCAFTPDGKILVSGAADQ 297
>BC117246-1|AAI17247.1| 707|Homo sapiens F-box and WD repeat domain
containing 7 protein.
Length = 707
Score = 103 bits (247), Expect = 5e-21
Identities = 76/288 (26%), Positives = 133/288 (46%), Gaps = 22/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+CL+ G SG ++VW T + TL GH G + N +++SGS
Sbjct: 384 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN--IIISGST 439
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
DRT+ VW T GH+S ++ + + +R +S R + VW +++G LH
Sbjct: 440 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVL 497
Query: 1089 TGPSASID-VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVS-HAERITCFALTADS 1146
G A++ V + + V D V++W +E ++ H R+ ++L D
Sbjct: 498 MGHVAAVRCVQYDGRRVVSGAYDFMVKVWD----PETETCLHTLQGHTNRV--YSLQFDG 551
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
HVV+GS+D S++VW ++ G L GH + + + + +VSG+ D + +WDI
Sbjct: 552 IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL---KDNILVSGNADSTVKIWDI 608
Query: 1207 NT---XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
T VTC++ + ++ ++D T+ +W+ K G
Sbjct: 609 KTGQCLQTLQGPNKHQSAVTCLQF--NKNFVITSSDDGTVKLWDLKTG 654
Score = 92.3 bits (219), Expect = 1e-17
Identities = 70/264 (26%), Positives = 121/264 (45%), Gaps = 16/264 (6%)
Query: 993 WQLSTHRLQATLNGHIGH-ITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
W+ + L GH H ITC+ F N ++SGS+D T+ VW T GH+
Sbjct: 365 WRRGELKSPKVLKGHDDHVITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTG 422
Query: 1052 AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLSDGD 1110
+ + M + + S+DR + VW ++G +H+ G ++++ + L+ K V D
Sbjct: 423 GVWSSQMRDNIIISGSTDRT--LKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRD 480
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
++R+W + G + + H + C + D + VV+G+ D +KVW +
Sbjct: 481 ATLRVWDIETG---QCLHVLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLH 535
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
L GH++ V + + VVSGS D ++ VWD+ T + +++ +
Sbjct: 536 TLQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN 592
Query: 1231 GTIAVSCAEDKTLIIWETKRGLAL 1254
I VS D T+ IW+ K G L
Sbjct: 593 --ILVSGNADSTVKIWDIKTGQCL 614
Score = 85.8 bits (203), Expect = 1e-15
Identities = 54/192 (28%), Positives = 92/192 (47%), Gaps = 7/192 (3%)
Query: 983 SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
SG +RVW + T + L GH+ + CV + V+SG+ D V VW +
Sbjct: 476 SGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKVWDPETETC 533
Query: 1043 SLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG-PSASIDVTLNM 1101
T +GH++ + +L DG +S ++ VW V++G +H+ TG S + + L
Sbjct: 534 LHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD 591
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
V + D++V+IW + G + + H +TC L + V+T S D ++K+W
Sbjct: 592 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTC--LQFNKNFVITSSDDGTVKLW 649
Query: 1162 KLDGGKLSQVLV 1173
L G+ + LV
Sbjct: 650 DLKTGEFIRNLV 661
Score = 77.8 bits (183), Expect = 3e-13
Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 12/230 (5%)
Query: 1035 WQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSAS 1094
W+ + KGH + T L G R +S + VW +G L + G +
Sbjct: 365 WRRGELKSPKVLKGHDDHVITCLQFC-GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGG 423
Query: 1095 IDVTLNMKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGS 1153
+ + ++S D ++++W+ G E H + C L + VV+GS
Sbjct: 424 VWSSQMRDNIIISGSTDRTLKVWNAETG---ECIHTLYGHTSTVRCMHL--HEKRVVSGS 478
Query: 1154 MDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXX 1213
D +L+VW ++ G+ VL+GH V CV + +VVSG++D + VWD T
Sbjct: 479 RDATLRVWDIETGQCLHVLMGHVAAVRCVQY---DGRRVVSGAYDFMVKVWDPETETCLH 535
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPL 1263
+V ++ DG VS + D ++ +W+ + G + + + H L
Sbjct: 536 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSL 583
Score = 72.1 bits (169), Expect = 1e-11
Identities = 54/222 (24%), Positives = 103/222 (46%), Gaps = 8/222 (3%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W+ + +HT GH+ ++ CM + + +++GS D ++ VWD+ T ++ H+
Sbjct: 444 KVWNAETGECIHTLYGHTSTVRCMHL--HEKRVVSGSRDATLRVWDIETGQCLHVLMGHV 501
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A V CV R V+SG D V + + L H V S++ DG ++G
Sbjct: 502 AAVRCVQYDGRR--VVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSG 557
Query: 797 SQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
S D ++ W+VE + T+T + DN+ L++ D+ + + TG L
Sbjct: 558 SLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQT 616
Query: 857 LK-RHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
L+ +K + C+ + + V D + L+ L + + +R
Sbjct: 617 LQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIR 658
Score = 64.5 bits (150), Expect = 3e-09
Identities = 52/236 (22%), Positives = 107/236 (45%), Gaps = 11/236 (4%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
G +V ++W ++ + T GH+G + + +++GS D ++ VW+
Sbjct: 391 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM--RDNIIISGSTDRTLKVWNA 448
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTS 783
T + H + V C+ ++ V+SG D+ + + + G + L G V +
Sbjct: 449 ETGECIHTLYGHTSTVRCMH--LHEKRVVSGSRDATLRVWDIETGQCLHVL---MGHVAA 503
Query: 784 VKVIQ-DGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNE 842
V+ +Q DG ++G+ D V W+ E T L T+ G ++ + D + +++ D
Sbjct: 504 VRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTL-QGHTNRVYSLQFDGIHVVSGSLDTS 562
Query: 843 LHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ + TG +H L H++ + D+ V+ G AD + ++ + + Q L+T
Sbjct: 563 IRVWDVETGNCIHTLTGHQS-LTSGMELKDNILVS-GNADSTVKIWDIKTGQCLQT 616
Score = 57.2 bits (132), Expect = 4e-07
Identities = 47/161 (29%), Positives = 74/161 (45%), Gaps = 9/161 (5%)
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQ 798
+ C+ NR ++SG DD+ + + S V G + L H G V S + ++D NI I+GS
Sbjct: 384 ITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQ-MRD-NIIISGST 439
Query: 799 DGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPL 857
D T+ WN E + T+ + + + V ++ D L + TG LH L
Sbjct: 440 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV--VSGSRDATLRVWDIETGQCLHVL 497
Query: 858 KRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
H A V+ CV +D RV G D + ++ + L T
Sbjct: 498 MGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHT 536
Score = 46.0 bits (104), Expect = 0.001
Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 7/122 (5%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R+ L G H+V ++W + + + +HT GH L + + L++G+ D
Sbjct: 543 RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDNILVSGNAD 600
Query: 716 TSVIVWDLHT---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVT 772
++V +WD+ T L +H + V C+ N++ VI+ DD V + L G +
Sbjct: 601 STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQ--FNKNFVITSSDDGTVKLWDLKTGEFIR 658
Query: 773 KL 774
L
Sbjct: 659 NL 660
>BC117244-1|AAI17245.1| 707|Homo sapiens F-box and WD repeat domain
containing 7 protein.
Length = 707
Score = 103 bits (247), Expect = 5e-21
Identities = 76/288 (26%), Positives = 133/288 (46%), Gaps = 22/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+CL+ G SG ++VW T + TL GH G + N +++SGS
Sbjct: 384 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN--IIISGST 439
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
DRT+ VW T GH+S ++ + + +R +S R + VW +++G LH
Sbjct: 440 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVL 497
Query: 1089 TGPSASID-VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVS-HAERITCFALTADS 1146
G A++ V + + V D V++W +E ++ H R+ ++L D
Sbjct: 498 MGHVAAVRCVQYDGRRVVSGAYDFMVKVWD----PETETCLHTLQGHTNRV--YSLQFDG 551
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
HVV+GS+D S++VW ++ G L GH + + + + +VSG+ D + +WDI
Sbjct: 552 IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL---KDNILVSGNADSTVKIWDI 608
Query: 1207 NT---XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
T VTC++ + ++ ++D T+ +W+ K G
Sbjct: 609 KTGQCLQTLQGPNKHQSAVTCLQF--NKNFVITSSDDGTVKLWDLKTG 654
Score = 92.3 bits (219), Expect = 1e-17
Identities = 70/264 (26%), Positives = 121/264 (45%), Gaps = 16/264 (6%)
Query: 993 WQLSTHRLQATLNGHIGH-ITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
W+ + L GH H ITC+ F N ++SGS+D T+ VW T GH+
Sbjct: 365 WRRGELKSPKVLKGHDDHVITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTG 422
Query: 1052 AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLSDGD 1110
+ + M + + S+DR + VW ++G +H+ G ++++ + L+ K V D
Sbjct: 423 GVWSSQMRDNIIISGSTDRT--LKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRD 480
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
++R+W + G + + H + C + D + VV+G+ D +KVW +
Sbjct: 481 ATLRVWDIETG---QCLHVLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLH 535
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
L GH++ V + + VVSGS D ++ VWD+ T + +++ +
Sbjct: 536 TLQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN 592
Query: 1231 GTIAVSCAEDKTLIIWETKRGLAL 1254
I VS D T+ IW+ K G L
Sbjct: 593 --ILVSGNADSTVKIWDIKTGQCL 614
Score = 85.8 bits (203), Expect = 1e-15
Identities = 54/192 (28%), Positives = 92/192 (47%), Gaps = 7/192 (3%)
Query: 983 SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
SG +RVW + T + L GH+ + CV + V+SG+ D V VW +
Sbjct: 476 SGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKVWDPETETC 533
Query: 1043 SLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG-PSASIDVTLNM 1101
T +GH++ + +L DG +S ++ VW V++G +H+ TG S + + L
Sbjct: 534 LHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD 591
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
V + D++V+IW + G + + H +TC L + V+T S D ++K+W
Sbjct: 592 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTC--LQFNKNFVITSSDDGTVKLW 649
Query: 1162 KLDGGKLSQVLV 1173
L G+ + LV
Sbjct: 650 DLKTGEFIRNLV 661
Score = 77.8 bits (183), Expect = 3e-13
Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 12/230 (5%)
Query: 1035 WQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSAS 1094
W+ + KGH + T L G R +S + VW +G L + G +
Sbjct: 365 WRRGELKSPKVLKGHDDHVITCLQFC-GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGG 423
Query: 1095 IDVTLNMKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGS 1153
+ + ++S D ++++W+ G E H + C L + VV+GS
Sbjct: 424 VWSSQMRDNIIISGSTDRTLKVWNAETG---ECIHTLYGHTSTVRCMHL--HEKRVVSGS 478
Query: 1154 MDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXX 1213
D +L+VW ++ G+ VL+GH V CV + +VVSG++D + VWD T
Sbjct: 479 RDATLRVWDIETGQCLHVLMGHVAAVRCVQY---DGRRVVSGAYDFMVKVWDPETETCLH 535
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPL 1263
+V ++ DG VS + D ++ +W+ + G + + + H L
Sbjct: 536 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSL 583
Score = 72.1 bits (169), Expect = 1e-11
Identities = 54/222 (24%), Positives = 103/222 (46%), Gaps = 8/222 (3%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W+ + +HT GH+ ++ CM + + +++GS D ++ VWD+ T ++ H+
Sbjct: 444 KVWNAETGECIHTLYGHTSTVRCMHL--HEKRVVSGSRDATLRVWDIETGQCLHVLMGHV 501
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A V CV R V+SG D V + + L H V S++ DG ++G
Sbjct: 502 AAVRCVQYDGRR--VVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSG 557
Query: 797 SQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
S D ++ W+VE + T+T + DN+ L++ D+ + + TG L
Sbjct: 558 SLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQT 616
Query: 857 LK-RHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
L+ +K + C+ + + V D + L+ L + + +R
Sbjct: 617 LQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIR 658
Score = 64.5 bits (150), Expect = 3e-09
Identities = 52/236 (22%), Positives = 107/236 (45%), Gaps = 11/236 (4%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
G +V ++W ++ + T GH+G + + +++GS D ++ VW+
Sbjct: 391 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM--RDNIIISGSTDRTLKVWNA 448
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTS 783
T + H + V C+ ++ V+SG D+ + + + G + L G V +
Sbjct: 449 ETGECIHTLYGHTSTVRCMH--LHEKRVVSGSRDATLRVWDIETGQCLHVL---MGHVAA 503
Query: 784 VKVIQ-DGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNE 842
V+ +Q DG ++G+ D V W+ E T L T+ G ++ + D + +++ D
Sbjct: 504 VRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTL-QGHTNRVYSLQFDGIHVVSGSLDTS 562
Query: 843 LHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ + TG +H L H++ + D+ V+ G AD + ++ + + Q L+T
Sbjct: 563 IRVWDVETGNCIHTLTGHQS-LTSGMELKDNILVS-GNADSTVKIWDIKTGQCLQT 616
Score = 57.2 bits (132), Expect = 4e-07
Identities = 47/161 (29%), Positives = 74/161 (45%), Gaps = 9/161 (5%)
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQ 798
+ C+ NR ++SG DD+ + + S V G + L H G V S + ++D NI I+GS
Sbjct: 384 ITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQ-MRD-NIIISGST 439
Query: 799 DGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPL 857
D T+ WN E + T+ + + + V ++ D L + TG LH L
Sbjct: 440 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV--VSGSRDATLRVWDIETGQCLHVL 497
Query: 858 KRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
H A V+ CV +D RV G D + ++ + L T
Sbjct: 498 MGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHT 536
Score = 46.0 bits (104), Expect = 0.001
Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 7/122 (5%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R+ L G H+V ++W + + + +HT GH L + + L++G+ D
Sbjct: 543 RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDNILVSGNAD 600
Query: 716 TSVIVWDLHT---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVT 772
++V +WD+ T L +H + V C+ N++ VI+ DD V + L G +
Sbjct: 601 STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQ--FNKNFVITSSDDGTVKLWDLKTGEFIR 658
Query: 773 KL 774
L
Sbjct: 659 NL 660
>BC037320-1|AAH37320.1| 621|Homo sapiens FBXW7 protein protein.
Length = 621
Score = 103 bits (247), Expect = 5e-21
Identities = 76/288 (26%), Positives = 133/288 (46%), Gaps = 22/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+CL+ G SG ++VW T + TL GH G + N +++SGS
Sbjct: 298 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN--IIISGST 353
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
DRT+ VW T GH+S ++ + + +R +S R + VW +++G LH
Sbjct: 354 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVL 411
Query: 1089 TGPSASID-VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVS-HAERITCFALTADS 1146
G A++ V + + V D V++W +E ++ H R+ ++L D
Sbjct: 412 MGHVAAVRCVRYDGRRVVSGAYDFMVKVWD----PETETCLHTLQGHTNRV--YSLQFDG 465
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
HVV+GS+D S++VW ++ G L GH + + + + +VSG+ D + +WDI
Sbjct: 466 IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL---KDNILVSGNADSTVKIWDI 522
Query: 1207 NT---XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
T VTC++ + ++ ++D T+ +W+ K G
Sbjct: 523 KTGQCLQTLQGPNKHQSAVTCLQF--NKNFVITSSDDGTVKLWDLKTG 568
Score = 94.7 bits (225), Expect = 2e-18
Identities = 71/264 (26%), Positives = 122/264 (46%), Gaps = 16/264 (6%)
Query: 993 WQLSTHRLQATLNGHIGH-ITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
W+ + LNGH H ITC+ F N ++SGS+D T+ VW T GH+
Sbjct: 279 WRRGELKSPKVLNGHDDHVITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTG 336
Query: 1052 AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLSDGD 1110
+ + M + + S+DR + VW ++G +H+ G ++++ + L+ K V D
Sbjct: 337 GVWSSQMRDNIIISGSTDRT--LKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRD 394
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
++R+W + G + + H + C + D + VV+G+ D +KVW +
Sbjct: 395 ATLRVWDIETG---QCLHVLMGHVAAVRC--VRYDGRRVVSGAYDFMVKVWDPETETCLH 449
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
L GH++ V + + VVSGS D ++ VWD+ T + +++ +
Sbjct: 450 TLQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN 506
Query: 1231 GTIAVSCAEDKTLIIWETKRGLAL 1254
I VS D T+ IW+ K G L
Sbjct: 507 --ILVSGNADSTVKIWDIKTGQCL 528
Score = 85.8 bits (203), Expect = 1e-15
Identities = 54/192 (28%), Positives = 92/192 (47%), Gaps = 7/192 (3%)
Query: 983 SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
SG +RVW + T + L GH+ + CV + V+SG+ D V VW +
Sbjct: 390 SGSRDATLRVWDIETGQCLHVLMGHVAAVRCVRYDGRR--VVSGAYDFMVKVWDPETETC 447
Query: 1043 SLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG-PSASIDVTLNM 1101
T +GH++ + +L DG +S ++ VW V++G +H+ TG S + + L
Sbjct: 448 LHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD 505
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
V + D++V+IW + G + + H +TC L + V+T S D ++K+W
Sbjct: 506 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTC--LQFNKNFVITSSDDGTVKLW 563
Query: 1162 KLDGGKLSQVLV 1173
L G+ + LV
Sbjct: 564 DLKTGEFIRNLV 575
Score = 75.8 bits (178), Expect = 1e-12
Identities = 56/230 (24%), Positives = 99/230 (43%), Gaps = 12/230 (5%)
Query: 1035 WQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSAS 1094
W+ + GH + T L G R +S + VW +G L + G +
Sbjct: 279 WRRGELKSPKVLNGHDDHVITCLQFC-GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGG 337
Query: 1095 IDVTLNMKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGS 1153
+ + ++S D ++++W+ G E H + C L + VV+GS
Sbjct: 338 VWSSQMRDNIIISGSTDRTLKVWNAETG---ECIHTLYGHTSTVRCMHL--HEKRVVSGS 392
Query: 1154 MDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXX 1213
D +L+VW ++ G+ VL+GH V CV + +VVSG++D + VWD T
Sbjct: 393 RDATLRVWDIETGQCLHVLMGHVAAVRCVRY---DGRRVVSGAYDFMVKVWDPETETCLH 449
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPL 1263
+V ++ DG VS + D ++ +W+ + G + + + H L
Sbjct: 450 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSL 497
Score = 72.1 bits (169), Expect = 1e-11
Identities = 54/222 (24%), Positives = 103/222 (46%), Gaps = 8/222 (3%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W+ + +HT GH+ ++ CM + + +++GS D ++ VWD+ T ++ H+
Sbjct: 358 KVWNAETGECIHTLYGHTSTVRCMHL--HEKRVVSGSRDATLRVWDIETGQCLHVLMGHV 415
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A V CV R V+SG D V + + L H V S++ DG ++G
Sbjct: 416 AAVRCVRYDGRR--VVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSG 471
Query: 797 SQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
S D ++ W+VE + T+T + DN+ L++ D+ + + TG L
Sbjct: 472 SLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQT 530
Query: 857 LK-RHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
L+ +K + C+ + + V D + L+ L + + +R
Sbjct: 531 LQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIR 572
Score = 64.1 bits (149), Expect = 4e-09
Identities = 51/235 (21%), Positives = 105/235 (44%), Gaps = 9/235 (3%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
G +V ++W ++ + T GH+G + + +++GS D ++ VW+
Sbjct: 305 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM--RDNIIISGSTDRTLKVWNA 362
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTS 783
T + H + V C+ ++ V+SG D+ + + + G + L H +V
Sbjct: 363 ETGECIHTLYGHTSTVRCMH--LHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRC 420
Query: 784 VKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNEL 843
V+ DG ++G+ D V W+ E T L T+ G ++ + D + +++ D +
Sbjct: 421 VR--YDGRRVVSGAYDFMVKVWDPETETCLHTL-QGHTNRVYSLQFDGIHVVSGSLDTSI 477
Query: 844 HLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ TG +H L H++ + D+ V+ G AD + ++ + + Q L+T
Sbjct: 478 RVWDVETGNCIHTLTGHQS-LTSGMELKDNILVS-GNADSTVKIWDIKTGQCLQT 530
Score = 57.2 bits (132), Expect = 4e-07
Identities = 47/161 (29%), Positives = 74/161 (45%), Gaps = 9/161 (5%)
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQ 798
+ C+ NR ++SG DD+ + + S V G + L H G V S + ++D NI I+GS
Sbjct: 298 ITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQ-MRD-NIIISGST 353
Query: 799 DGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPL 857
D T+ WN E + T+ + + + V ++ D L + TG LH L
Sbjct: 354 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV--VSGSRDATLRVWDIETGQCLHVL 411
Query: 858 KRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
H A V+ CV +D RV G D + ++ + L T
Sbjct: 412 MGHVAAVR--CVRYDGRRVVSGAYDFMVKVWDPETETCLHT 450
Score = 46.0 bits (104), Expect = 0.001
Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 7/122 (5%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R+ L G H+V ++W + + + +HT GH L + + L++G+ D
Sbjct: 457 RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDNILVSGNAD 514
Query: 716 TSVIVWDLHT---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVT 772
++V +WD+ T L +H + V C+ N++ VI+ DD V + L G +
Sbjct: 515 STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQ--FNKNFVITSSDDGTVKLWDLKTGEFIR 572
Query: 773 KL 774
L
Sbjct: 573 NL 574
>AY049984-1|AAL07271.1| 707|Homo sapiens F-box protein CDC4 protein.
Length = 707
Score = 103 bits (247), Expect = 5e-21
Identities = 76/288 (26%), Positives = 133/288 (46%), Gaps = 22/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+CL+ G SG ++VW T + TL GH G + N +++SGS
Sbjct: 384 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN--IIISGST 439
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
DRT+ VW T GH+S ++ + + +R +S R + VW +++G LH
Sbjct: 440 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVL 497
Query: 1089 TGPSASID-VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVS-HAERITCFALTADS 1146
G A++ V + + V D V++W +E ++ H R+ ++L D
Sbjct: 498 MGHVAAVRCVQYDGRRVVSGAYDFMVKVWD----PETETCLHTLQGHTNRV--YSLQFDG 551
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
HVV+GS+D S++VW ++ G L GH + + + + +VSG+ D + +WDI
Sbjct: 552 IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL---KDNILVSGNADSTVKIWDI 608
Query: 1207 NT---XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
T VTC++ + ++ ++D T+ +W+ K G
Sbjct: 609 KTGQCLQTLQGPNKHQSAVTCLQF--NKNFVITSSDDGTVKLWDLKTG 654
Score = 92.3 bits (219), Expect = 1e-17
Identities = 70/264 (26%), Positives = 121/264 (45%), Gaps = 16/264 (6%)
Query: 993 WQLSTHRLQATLNGHIGH-ITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
W+ + L GH H ITC+ F N ++SGS+D T+ VW T GH+
Sbjct: 365 WRRGELKSPKVLKGHDDHVITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTG 422
Query: 1052 AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLSDGD 1110
+ + M + + S+DR + VW ++G +H+ G ++++ + L+ K V D
Sbjct: 423 GVWSSQMRDNIIISGSTDRT--LKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRD 480
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
++R+W + G + + H + C + D + VV+G+ D +KVW +
Sbjct: 481 ATLRVWDIETG---QCLHVLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLH 535
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
L GH++ V + + VVSGS D ++ VWD+ T + +++ +
Sbjct: 536 TLQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN 592
Query: 1231 GTIAVSCAEDKTLIIWETKRGLAL 1254
I VS D T+ IW+ K G L
Sbjct: 593 --ILVSGNADSTVKIWDIKTGQCL 614
Score = 85.8 bits (203), Expect = 1e-15
Identities = 54/192 (28%), Positives = 92/192 (47%), Gaps = 7/192 (3%)
Query: 983 SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
SG +RVW + T + L GH+ + CV + V+SG+ D V VW +
Sbjct: 476 SGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKVWDPETETC 533
Query: 1043 SLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG-PSASIDVTLNM 1101
T +GH++ + +L DG +S ++ VW V++G +H+ TG S + + L
Sbjct: 534 LHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD 591
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
V + D++V+IW + G + + H +TC L + V+T S D ++K+W
Sbjct: 592 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTC--LQFNKNFVITSSDDGTVKLW 649
Query: 1162 KLDGGKLSQVLV 1173
L G+ + LV
Sbjct: 650 DLKTGEFIRNLV 661
Score = 77.8 bits (183), Expect = 3e-13
Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 12/230 (5%)
Query: 1035 WQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSAS 1094
W+ + KGH + T L G R +S + VW +G L + G +
Sbjct: 365 WRRGELKSPKVLKGHDDHVITCLQFC-GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGG 423
Query: 1095 IDVTLNMKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGS 1153
+ + ++S D ++++W+ G E H + C L + VV+GS
Sbjct: 424 VWSSQMRDNIIISGSTDRTLKVWNAETG---ECIHTLYGHTSTVRCMHL--HEKRVVSGS 478
Query: 1154 MDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXX 1213
D +L+VW ++ G+ VL+GH V CV + +VVSG++D + VWD T
Sbjct: 479 RDATLRVWDIETGQCLHVLMGHVAAVRCVQY---DGRRVVSGAYDFMVKVWDPETETCLH 535
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPL 1263
+V ++ DG VS + D ++ +W+ + G + + + H L
Sbjct: 536 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSL 583
Score = 72.1 bits (169), Expect = 1e-11
Identities = 54/222 (24%), Positives = 103/222 (46%), Gaps = 8/222 (3%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W+ + +HT GH+ ++ CM + + +++GS D ++ VWD+ T ++ H+
Sbjct: 444 KVWNAETGECIHTLYGHTSTVRCMHL--HEKRVVSGSRDATLRVWDIETGQCLHVLMGHV 501
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A V CV R V+SG D V + + L H V S++ DG ++G
Sbjct: 502 AAVRCVQYDGRR--VVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSG 557
Query: 797 SQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
S D ++ W+VE + T+T + DN+ L++ D+ + + TG L
Sbjct: 558 SLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQT 616
Query: 857 LK-RHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
L+ +K + C+ + + V D + L+ L + + +R
Sbjct: 617 LQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIR 658
Score = 64.5 bits (150), Expect = 3e-09
Identities = 52/236 (22%), Positives = 107/236 (45%), Gaps = 11/236 (4%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
G +V ++W ++ + T GH+G + + +++GS D ++ VW+
Sbjct: 391 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM--RDNIIISGSTDRTLKVWNA 448
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTS 783
T + H + V C+ ++ V+SG D+ + + + G + L G V +
Sbjct: 449 ETGECIHTLYGHTSTVRCMH--LHEKRVVSGSRDATLRVWDIETGQCLHVL---MGHVAA 503
Query: 784 VKVIQ-DGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNE 842
V+ +Q DG ++G+ D V W+ E T L T+ G ++ + D + +++ D
Sbjct: 504 VRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTL-QGHTNRVYSLQFDGIHVVSGSLDTS 562
Query: 843 LHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ + TG +H L H++ + D+ V+ G AD + ++ + + Q L+T
Sbjct: 563 IRVWDVETGNCIHTLTGHQS-LTSGMELKDNILVS-GNADSTVKIWDIKTGQCLQT 616
Score = 57.2 bits (132), Expect = 4e-07
Identities = 47/161 (29%), Positives = 74/161 (45%), Gaps = 9/161 (5%)
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQ 798
+ C+ NR ++SG DD+ + + S V G + L H G V S + ++D NI I+GS
Sbjct: 384 ITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQ-MRD-NIIISGST 439
Query: 799 DGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPL 857
D T+ WN E + T+ + + + V ++ D L + TG LH L
Sbjct: 440 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV--VSGSRDATLRVWDIETGQCLHVL 497
Query: 858 KRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
H A V+ CV +D RV G D + ++ + L T
Sbjct: 498 MGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHT 536
Score = 46.0 bits (104), Expect = 0.001
Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 7/122 (5%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R+ L G H+V ++W + + + +HT GH L + + L++G+ D
Sbjct: 543 RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDNILVSGNAD 600
Query: 716 TSVIVWDLHT---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVT 772
++V +WD+ T L +H + V C+ N++ VI+ DD V + L G +
Sbjct: 601 STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQ--FNKNFVITSSDDGTVKLWDLKTGEFIR 658
Query: 773 KL 774
L
Sbjct: 659 NL 660
>AY033553-1|AAK57547.1| 627|Homo sapiens F-box protein FBW7 protein.
Length = 627
Score = 103 bits (247), Expect = 5e-21
Identities = 76/288 (26%), Positives = 133/288 (46%), Gaps = 22/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+CL+ G SG ++VW T + TL GH G + N +++SGS
Sbjct: 304 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN--IIISGST 359
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
DRT+ VW T GH+S ++ + + +R +S R + VW +++G LH
Sbjct: 360 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVL 417
Query: 1089 TGPSASID-VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVS-HAERITCFALTADS 1146
G A++ V + + V D V++W +E ++ H R+ ++L D
Sbjct: 418 MGHVAAVRCVQYDGRRVVSGAYDFMVKVWD----PETETCLHTLQGHTNRV--YSLQFDG 471
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
HVV+GS+D S++VW ++ G L GH + + + + +VSG+ D + +WDI
Sbjct: 472 IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL---KDNILVSGNADSTVKIWDI 528
Query: 1207 NT---XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
T VTC++ + ++ ++D T+ +W+ K G
Sbjct: 529 KTGQCLQTLQGPNKHQSAVTCLQF--NKNFVITSSDDGTVKLWDLKTG 574
Score = 92.3 bits (219), Expect = 1e-17
Identities = 70/264 (26%), Positives = 121/264 (45%), Gaps = 16/264 (6%)
Query: 993 WQLSTHRLQATLNGHIGH-ITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
W+ + L GH H ITC+ F N ++SGS+D T+ VW T GH+
Sbjct: 285 WRRGELKSPKVLKGHDDHVITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTG 342
Query: 1052 AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLSDGD 1110
+ + M + + S+DR + VW ++G +H+ G ++++ + L+ K V D
Sbjct: 343 GVWSSQMRDNIIISGSTDRT--LKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRD 400
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
++R+W + G + + H + C + D + VV+G+ D +KVW +
Sbjct: 401 ATLRVWDIETG---QCLHVLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLH 455
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
L GH++ V + + VVSGS D ++ VWD+ T + +++ +
Sbjct: 456 TLQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN 512
Query: 1231 GTIAVSCAEDKTLIIWETKRGLAL 1254
I VS D T+ IW+ K G L
Sbjct: 513 --ILVSGNADSTVKIWDIKTGQCL 534
Score = 85.8 bits (203), Expect = 1e-15
Identities = 54/192 (28%), Positives = 92/192 (47%), Gaps = 7/192 (3%)
Query: 983 SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
SG +RVW + T + L GH+ + CV + V+SG+ D V VW +
Sbjct: 396 SGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKVWDPETETC 453
Query: 1043 SLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG-PSASIDVTLNM 1101
T +GH++ + +L DG +S ++ VW V++G +H+ TG S + + L
Sbjct: 454 LHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD 511
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
V + D++V+IW + G + + H +TC L + V+T S D ++K+W
Sbjct: 512 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTC--LQFNKNFVITSSDDGTVKLW 569
Query: 1162 KLDGGKLSQVLV 1173
L G+ + LV
Sbjct: 570 DLKTGEFIRNLV 581
Score = 77.8 bits (183), Expect = 3e-13
Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 12/230 (5%)
Query: 1035 WQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSAS 1094
W+ + KGH + T L G R +S + VW +G L + G +
Sbjct: 285 WRRGELKSPKVLKGHDDHVITCLQFC-GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGG 343
Query: 1095 IDVTLNMKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGS 1153
+ + ++S D ++++W+ G E H + C L + VV+GS
Sbjct: 344 VWSSQMRDNIIISGSTDRTLKVWNAETG---ECIHTLYGHTSTVRCMHL--HEKRVVSGS 398
Query: 1154 MDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXX 1213
D +L+VW ++ G+ VL+GH V CV + +VVSG++D + VWD T
Sbjct: 399 RDATLRVWDIETGQCLHVLMGHVAAVRCVQY---DGRRVVSGAYDFMVKVWDPETETCLH 455
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPL 1263
+V ++ DG VS + D ++ +W+ + G + + + H L
Sbjct: 456 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSL 503
Score = 72.1 bits (169), Expect = 1e-11
Identities = 54/222 (24%), Positives = 103/222 (46%), Gaps = 8/222 (3%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W+ + +HT GH+ ++ CM + + +++GS D ++ VWD+ T ++ H+
Sbjct: 364 KVWNAETGECIHTLYGHTSTVRCMHL--HEKRVVSGSRDATLRVWDIETGQCLHVLMGHV 421
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A V CV R V+SG D V + + L H V S++ DG ++G
Sbjct: 422 AAVRCVQYDGRR--VVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSG 477
Query: 797 SQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
S D ++ W+VE + T+T + DN+ L++ D+ + + TG L
Sbjct: 478 SLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQT 536
Query: 857 LK-RHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
L+ +K + C+ + + V D + L+ L + + +R
Sbjct: 537 LQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIR 578
Score = 64.5 bits (150), Expect = 3e-09
Identities = 52/236 (22%), Positives = 107/236 (45%), Gaps = 11/236 (4%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
G +V ++W ++ + T GH+G + + +++GS D ++ VW+
Sbjct: 311 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM--RDNIIISGSTDRTLKVWNA 368
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTS 783
T + H + V C+ ++ V+SG D+ + + + G + L G V +
Sbjct: 369 ETGECIHTLYGHTSTVRCMH--LHEKRVVSGSRDATLRVWDIETGQCLHVL---MGHVAA 423
Query: 784 VKVIQ-DGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNE 842
V+ +Q DG ++G+ D V W+ E T L T+ G ++ + D + +++ D
Sbjct: 424 VRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTL-QGHTNRVYSLQFDGIHVVSGSLDTS 482
Query: 843 LHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ + TG +H L H++ + D+ V+ G AD + ++ + + Q L+T
Sbjct: 483 IRVWDVETGNCIHTLTGHQS-LTSGMELKDNILVS-GNADSTVKIWDIKTGQCLQT 536
Score = 57.2 bits (132), Expect = 4e-07
Identities = 47/161 (29%), Positives = 74/161 (45%), Gaps = 9/161 (5%)
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQ 798
+ C+ NR ++SG DD+ + + S V G + L H G V S + ++D NI I+GS
Sbjct: 304 ITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQ-MRD-NIIISGST 359
Query: 799 DGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPL 857
D T+ WN E + T+ + + + V ++ D L + TG LH L
Sbjct: 360 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV--VSGSRDATLRVWDIETGQCLHVL 417
Query: 858 KRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
H A V+ CV +D RV G D + ++ + L T
Sbjct: 418 MGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHT 456
Score = 46.0 bits (104), Expect = 0.001
Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 7/122 (5%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R+ L G H+V ++W + + + +HT GH L + + L++G+ D
Sbjct: 463 RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDNILVSGNAD 520
Query: 716 TSVIVWDLHT---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVT 772
++V +WD+ T L +H + V C+ N++ VI+ DD V + L G +
Sbjct: 521 STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQ--FNKNFVITSSDDGTVKLWDLKTGEFIR 578
Query: 773 KL 774
L
Sbjct: 579 NL 580
>AY008274-1|AAG16640.1| 589|Homo sapiens F-box protein SEL10 protein.
Length = 589
Score = 103 bits (247), Expect = 5e-21
Identities = 76/288 (26%), Positives = 133/288 (46%), Gaps = 22/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+CL+ G SG ++VW T + TL GH G + N +++SGS
Sbjct: 266 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN--IIISGST 321
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
DRT+ VW T GH+S ++ + + +R +S R + VW +++G LH
Sbjct: 322 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVL 379
Query: 1089 TGPSASID-VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVS-HAERITCFALTADS 1146
G A++ V + + V D V++W +E ++ H R+ ++L D
Sbjct: 380 MGHVAAVRCVQYDGRRVVSGAYDFMVKVWD----PETETCLHTLQGHTNRV--YSLQFDG 433
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
HVV+GS+D S++VW ++ G L GH + + + + +VSG+ D + +WDI
Sbjct: 434 IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL---KDNILVSGNADSTVKIWDI 490
Query: 1207 NT---XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
T VTC++ + ++ ++D T+ +W+ K G
Sbjct: 491 KTGQCLQTLQGPNKHQSAVTCLQF--NKNFVITSSDDGTVKLWDLKTG 536
Score = 92.3 bits (219), Expect = 1e-17
Identities = 70/264 (26%), Positives = 121/264 (45%), Gaps = 16/264 (6%)
Query: 993 WQLSTHRLQATLNGHIGH-ITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
W+ + L GH H ITC+ F N ++SGS+D T+ VW T GH+
Sbjct: 247 WRRGELKSPKVLKGHDDHVITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTG 304
Query: 1052 AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLSDGD 1110
+ + M + + S+DR + VW ++G +H+ G ++++ + L+ K V D
Sbjct: 305 GVWSSQMRDNIIISGSTDRT--LKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRD 362
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
++R+W + G + + H + C + D + VV+G+ D +KVW +
Sbjct: 363 ATLRVWDIETG---QCLHVLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLH 417
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
L GH++ V + + VVSGS D ++ VWD+ T + +++ +
Sbjct: 418 TLQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN 474
Query: 1231 GTIAVSCAEDKTLIIWETKRGLAL 1254
I VS D T+ IW+ K G L
Sbjct: 475 --ILVSGNADSTVKIWDIKTGQCL 496
Score = 85.8 bits (203), Expect = 1e-15
Identities = 54/192 (28%), Positives = 92/192 (47%), Gaps = 7/192 (3%)
Query: 983 SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
SG +RVW + T + L GH+ + CV + V+SG+ D V VW +
Sbjct: 358 SGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKVWDPETETC 415
Query: 1043 SLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG-PSASIDVTLNM 1101
T +GH++ + +L DG +S ++ VW V++G +H+ TG S + + L
Sbjct: 416 LHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD 473
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
V + D++V+IW + G + + H +TC L + V+T S D ++K+W
Sbjct: 474 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTC--LQFNKNFVITSSDDGTVKLW 531
Query: 1162 KLDGGKLSQVLV 1173
L G+ + LV
Sbjct: 532 DLKTGEFIRNLV 543
Score = 77.8 bits (183), Expect = 3e-13
Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 12/230 (5%)
Query: 1035 WQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSAS 1094
W+ + KGH + T L G R +S + VW +G L + G +
Sbjct: 247 WRRGELKSPKVLKGHDDHVITCLQFC-GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGG 305
Query: 1095 IDVTLNMKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGS 1153
+ + ++S D ++++W+ G E H + C L + VV+GS
Sbjct: 306 VWSSQMRDNIIISGSTDRTLKVWNAETG---ECIHTLYGHTSTVRCMHL--HEKRVVSGS 360
Query: 1154 MDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXX 1213
D +L+VW ++ G+ VL+GH V CV + +VVSG++D + VWD T
Sbjct: 361 RDATLRVWDIETGQCLHVLMGHVAAVRCVQY---DGRRVVSGAYDFMVKVWDPETETCLH 417
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPL 1263
+V ++ DG VS + D ++ +W+ + G + + + H L
Sbjct: 418 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSL 465
Score = 72.1 bits (169), Expect = 1e-11
Identities = 54/222 (24%), Positives = 103/222 (46%), Gaps = 8/222 (3%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W+ + +HT GH+ ++ CM + + +++GS D ++ VWD+ T ++ H+
Sbjct: 326 KVWNAETGECIHTLYGHTSTVRCMHL--HEKRVVSGSRDATLRVWDIETGQCLHVLMGHV 383
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A V CV R V+SG D V + + L H V S++ DG ++G
Sbjct: 384 AAVRCVQYDGRR--VVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSG 439
Query: 797 SQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
S D ++ W+VE + T+T + DN+ L++ D+ + + TG L
Sbjct: 440 SLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQT 498
Query: 857 LK-RHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
L+ +K + C+ + + V D + L+ L + + +R
Sbjct: 499 LQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIR 540
Score = 64.5 bits (150), Expect = 3e-09
Identities = 52/236 (22%), Positives = 107/236 (45%), Gaps = 11/236 (4%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
G +V ++W ++ + T GH+G + + +++GS D ++ VW+
Sbjct: 273 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM--RDNIIISGSTDRTLKVWNA 330
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTS 783
T + H + V C+ ++ V+SG D+ + + + G + L G V +
Sbjct: 331 ETGECIHTLYGHTSTVRCMH--LHEKRVVSGSRDATLRVWDIETGQCLHVL---MGHVAA 385
Query: 784 VKVIQ-DGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNE 842
V+ +Q DG ++G+ D V W+ E T L T+ G ++ + D + +++ D
Sbjct: 386 VRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTL-QGHTNRVYSLQFDGIHVVSGSLDTS 444
Query: 843 LHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ + TG +H L H++ + D+ V+ G AD + ++ + + Q L+T
Sbjct: 445 IRVWDVETGNCIHTLTGHQS-LTSGMELKDNILVS-GNADSTVKIWDIKTGQCLQT 498
Score = 57.2 bits (132), Expect = 4e-07
Identities = 47/161 (29%), Positives = 74/161 (45%), Gaps = 9/161 (5%)
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQ 798
+ C+ NR ++SG DD+ + + S V G + L H G V S + ++D NI I+GS
Sbjct: 266 ITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQ-MRD-NIIISGST 321
Query: 799 DGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPL 857
D T+ WN E + T+ + + + V ++ D L + TG LH L
Sbjct: 322 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV--VSGSRDATLRVWDIETGQCLHVL 379
Query: 858 KRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
H A V+ CV +D RV G D + ++ + L T
Sbjct: 380 MGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHT 418
Score = 46.0 bits (104), Expect = 0.001
Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 7/122 (5%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R+ L G H+V ++W + + + +HT GH L + + L++G+ D
Sbjct: 425 RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDNILVSGNAD 482
Query: 716 TSVIVWDLHT---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVT 772
++V +WD+ T L +H + V C+ N++ VI+ DD V + L G +
Sbjct: 483 STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQ--FNKNFVITSSDDGTVKLWDLKTGEFIR 540
Query: 773 KL 774
L
Sbjct: 541 NL 542
>AK223449-1|BAD97169.1| 627|Homo sapiens F-box protein FBW7 isoform 2
variant protein.
Length = 627
Score = 103 bits (247), Expect = 5e-21
Identities = 76/288 (26%), Positives = 133/288 (46%), Gaps = 22/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+CL+ G SG ++VW T + TL GH G + N +++SGS
Sbjct: 304 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN--IIISGST 359
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
DRT+ VW T GH+S ++ + + +R +S R + VW +++G LH
Sbjct: 360 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVL 417
Query: 1089 TGPSASID-VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVS-HAERITCFALTADS 1146
G A++ V + + V D V++W +E ++ H R+ ++L D
Sbjct: 418 MGHVAAVRCVQYDGRRVVSGAYDFMVKVWD----PETETCLHTLQGHTNRV--YSLQFDG 471
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
HVV+GS+D S++VW ++ G L GH + + + + +VSG+ D + +WDI
Sbjct: 472 IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL---KDNILVSGNADSTVKIWDI 528
Query: 1207 NT---XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
T VTC++ + ++ ++D T+ +W+ K G
Sbjct: 529 KTGQCLQTLQGPNKHQSAVTCLQF--NKNFVITSSDDGTVKLWDLKTG 574
Score = 92.3 bits (219), Expect = 1e-17
Identities = 70/264 (26%), Positives = 121/264 (45%), Gaps = 16/264 (6%)
Query: 993 WQLSTHRLQATLNGHIGH-ITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
W+ + L GH H ITC+ F N ++SGS+D T+ VW T GH+
Sbjct: 285 WRRGELKSPKVLKGHDDHVITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTG 342
Query: 1052 AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLSDGD 1110
+ + M + + S+DR + VW ++G +H+ G ++++ + L+ K V D
Sbjct: 343 GVWSSQMRDNIIISGSTDRT--LKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRD 400
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
++R+W + G + + H + C + D + VV+G+ D +KVW +
Sbjct: 401 ATLRVWDIETG---QCLHVLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLH 455
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
L GH++ V + + VVSGS D ++ VWD+ T + +++ +
Sbjct: 456 TLQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN 512
Query: 1231 GTIAVSCAEDKTLIIWETKRGLAL 1254
I VS D T+ IW+ K G L
Sbjct: 513 --ILVSGNADSTVKIWDIKTGQCL 534
Score = 85.8 bits (203), Expect = 1e-15
Identities = 54/192 (28%), Positives = 92/192 (47%), Gaps = 7/192 (3%)
Query: 983 SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
SG +RVW + T + L GH+ + CV + V+SG+ D V VW +
Sbjct: 396 SGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKVWDPETETC 453
Query: 1043 SLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG-PSASIDVTLNM 1101
T +GH++ + +L DG +S ++ VW V++G +H+ TG S + + L
Sbjct: 454 LHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD 511
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
V + D++V+IW + G + + H +TC L + V+T S D ++K+W
Sbjct: 512 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTC--LQFNKNFVITSSDDGTVKLW 569
Query: 1162 KLDGGKLSQVLV 1173
L G+ + LV
Sbjct: 570 DLKTGEFIRNLV 581
Score = 77.8 bits (183), Expect = 3e-13
Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 12/230 (5%)
Query: 1035 WQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSAS 1094
W+ + KGH + T L G R +S + VW +G L + G +
Sbjct: 285 WRRGELKSPKVLKGHDDHVITCLQFC-GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGG 343
Query: 1095 IDVTLNMKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGS 1153
+ + ++S D ++++W+ G E H + C L + VV+GS
Sbjct: 344 VWSSQMRDNIIISGSTDRTLKVWNAETG---ECIHTLYGHTSTVRCMHL--HEKRVVSGS 398
Query: 1154 MDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXX 1213
D +L+VW ++ G+ VL+GH V CV + +VVSG++D + VWD T
Sbjct: 399 RDATLRVWDIETGQCLHVLMGHVAAVRCVQY---DGRRVVSGAYDFMVKVWDPETETCLH 455
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPL 1263
+V ++ DG VS + D ++ +W+ + G + + + H L
Sbjct: 456 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSL 503
Score = 72.1 bits (169), Expect = 1e-11
Identities = 54/222 (24%), Positives = 103/222 (46%), Gaps = 8/222 (3%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W+ + +HT GH+ ++ CM + + +++GS D ++ VWD+ T ++ H+
Sbjct: 364 KVWNAETGECIHTLYGHTSTVRCMHL--HEKRVVSGSRDATLRVWDIETGQCLHVLMGHV 421
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A V CV R V+SG D V + + L H V S++ DG ++G
Sbjct: 422 AAVRCVQYDGRR--VVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSG 477
Query: 797 SQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
S D ++ W+VE + T+T + DN+ L++ D+ + + TG L
Sbjct: 478 SLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQT 536
Query: 857 LK-RHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
L+ +K + C+ + + V D + L+ L + + +R
Sbjct: 537 LQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIR 578
Score = 64.5 bits (150), Expect = 3e-09
Identities = 52/236 (22%), Positives = 107/236 (45%), Gaps = 11/236 (4%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
G +V ++W ++ + T GH+G + + +++GS D ++ VW+
Sbjct: 311 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM--RDNIIISGSTDRTLKVWNA 368
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTS 783
T + H + V C+ ++ V+SG D+ + + + G + L G V +
Sbjct: 369 ETGECIHTLYGHTSTVRCMH--LHEKRVVSGSRDATLRVWDIETGQCLHVL---MGHVAA 423
Query: 784 VKVIQ-DGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNE 842
V+ +Q DG ++G+ D V W+ E T L T+ G ++ + D + +++ D
Sbjct: 424 VRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTL-QGHTNRVYSLQFDGIHVVSGSLDTS 482
Query: 843 LHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ + TG +H L H++ + D+ V+ G AD + ++ + + Q L+T
Sbjct: 483 IRVWDVETGNCIHTLTGHQS-LTSGMELKDNILVS-GNADSTVKIWDIKTGQCLQT 536
Score = 57.2 bits (132), Expect = 4e-07
Identities = 47/161 (29%), Positives = 74/161 (45%), Gaps = 9/161 (5%)
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQ 798
+ C+ NR ++SG DD+ + + S V G + L H G V S + ++D NI I+GS
Sbjct: 304 ITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQ-MRD-NIIISGST 359
Query: 799 DGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPL 857
D T+ WN E + T+ + + + V ++ D L + TG LH L
Sbjct: 360 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV--VSGSRDATLRVWDIETGQCLHVL 417
Query: 858 KRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
H A V+ CV +D RV G D + ++ + L T
Sbjct: 418 MGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHT 456
Score = 46.0 bits (104), Expect = 0.001
Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 7/122 (5%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R+ L G H+V ++W + + + +HT GH L + + L++G+ D
Sbjct: 463 RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDNILVSGNAD 520
Query: 716 TSVIVWDLHT---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVT 772
++V +WD+ T L +H + V C+ N++ VI+ DD V + L G +
Sbjct: 521 STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQ--FNKNFVITSSDDGTVKLWDLKTGEFIR 578
Query: 773 KL 774
L
Sbjct: 579 NL 580
>AK001933-1|BAA91986.1| 553|Homo sapiens protein ( Homo sapiens cDNA
FLJ11071 fis, clone PLACE1004937, moderately similar to
SEL-10 PROTEIN. ).
Length = 553
Score = 103 bits (247), Expect = 5e-21
Identities = 76/288 (26%), Positives = 133/288 (46%), Gaps = 22/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+CL+ G SG ++VW T + TL GH G + N +++SGS
Sbjct: 230 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN--IIISGST 285
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
DRT+ VW T GH+S ++ + + +R +S R + VW +++G LH
Sbjct: 286 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVL 343
Query: 1089 TGPSASID-VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVS-HAERITCFALTADS 1146
G A++ V + + V D V++W +E ++ H R+ ++L D
Sbjct: 344 MGHVAAVRCVQYDGRRVVSGAYDFMVKVWD----PETETCLHTLQGHTNRV--YSLQFDG 397
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
HVV+GS+D S++VW ++ G L GH + + + + +VSG+ D + +WDI
Sbjct: 398 IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL---KDNILVSGNADSTVKIWDI 454
Query: 1207 NT---XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
T VTC++ + ++ ++D T+ +W+ K G
Sbjct: 455 KTGQCLQTLQGPNKHQSAVTCLQF--NKNFVITSSDDGTVKLWDLKTG 500
Score = 92.3 bits (219), Expect = 1e-17
Identities = 70/264 (26%), Positives = 121/264 (45%), Gaps = 16/264 (6%)
Query: 993 WQLSTHRLQATLNGHIGH-ITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
W+ + L GH H ITC+ F N ++SGS+D T+ VW T GH+
Sbjct: 211 WRRGELKSPKVLKGHDDHVITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTG 268
Query: 1052 AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLSDGD 1110
+ + M + + S+DR + VW ++G +H+ G ++++ + L+ K V D
Sbjct: 269 GVWSSQMRDNIIISGSTDRT--LKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRD 326
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
++R+W + G + + H + C + D + VV+G+ D +KVW +
Sbjct: 327 ATLRVWDIETG---QCLHVLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLH 381
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
L GH++ V + + VVSGS D ++ VWD+ T + +++ +
Sbjct: 382 TLQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN 438
Query: 1231 GTIAVSCAEDKTLIIWETKRGLAL 1254
I VS D T+ IW+ K G L
Sbjct: 439 --ILVSGNADSTVKIWDIKTGQCL 460
Score = 85.8 bits (203), Expect = 1e-15
Identities = 54/192 (28%), Positives = 92/192 (47%), Gaps = 7/192 (3%)
Query: 983 SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
SG +RVW + T + L GH+ + CV + V+SG+ D V VW +
Sbjct: 322 SGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKVWDPETETC 379
Query: 1043 SLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG-PSASIDVTLNM 1101
T +GH++ + +L DG +S ++ VW V++G +H+ TG S + + L
Sbjct: 380 LHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD 437
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
V + D++V+IW + G + + H +TC L + V+T S D ++K+W
Sbjct: 438 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTC--LQFNKNFVITSSDDGTVKLW 495
Query: 1162 KLDGGKLSQVLV 1173
L G+ + LV
Sbjct: 496 DLKTGEFIRNLV 507
Score = 77.8 bits (183), Expect = 3e-13
Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 12/230 (5%)
Query: 1035 WQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSAS 1094
W+ + KGH + T L G R +S + VW +G L + G +
Sbjct: 211 WRRGELKSPKVLKGHDDHVITCLQFC-GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGG 269
Query: 1095 IDVTLNMKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGS 1153
+ + ++S D ++++W+ G E H + C L + VV+GS
Sbjct: 270 VWSSQMRDNIIISGSTDRTLKVWNAETG---ECIHTLYGHTSTVRCMHL--HEKRVVSGS 324
Query: 1154 MDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXX 1213
D +L+VW ++ G+ VL+GH V CV + +VVSG++D + VWD T
Sbjct: 325 RDATLRVWDIETGQCLHVLMGHVAAVRCVQY---DGRRVVSGAYDFMVKVWDPETETCLH 381
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPL 1263
+V ++ DG VS + D ++ +W+ + G + + + H L
Sbjct: 382 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSL 429
Score = 72.1 bits (169), Expect = 1e-11
Identities = 54/222 (24%), Positives = 103/222 (46%), Gaps = 8/222 (3%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W+ + +HT GH+ ++ CM + + +++GS D ++ VWD+ T ++ H+
Sbjct: 290 KVWNAETGECIHTLYGHTSTVRCMHL--HEKRVVSGSRDATLRVWDIETGQCLHVLMGHV 347
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A V CV R V+SG D V + + L H V S++ DG ++G
Sbjct: 348 AAVRCVQYDGRR--VVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSG 403
Query: 797 SQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
S D ++ W+VE + T+T + DN+ L++ D+ + + TG L
Sbjct: 404 SLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQT 462
Query: 857 LK-RHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
L+ +K + C+ + + V D + L+ L + + +R
Sbjct: 463 LQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIR 504
Score = 64.5 bits (150), Expect = 3e-09
Identities = 52/236 (22%), Positives = 107/236 (45%), Gaps = 11/236 (4%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
G +V ++W ++ + T GH+G + + +++GS D ++ VW+
Sbjct: 237 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM--RDNIIISGSTDRTLKVWNA 294
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTS 783
T + H + V C+ ++ V+SG D+ + + + G + L G V +
Sbjct: 295 ETGECIHTLYGHTSTVRCMH--LHEKRVVSGSRDATLRVWDIETGQCLHVL---MGHVAA 349
Query: 784 VKVIQ-DGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNE 842
V+ +Q DG ++G+ D V W+ E T L T+ G ++ + D + +++ D
Sbjct: 350 VRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTL-QGHTNRVYSLQFDGIHVVSGSLDTS 408
Query: 843 LHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ + TG +H L H++ + D+ V+ G AD + ++ + + Q L+T
Sbjct: 409 IRVWDVETGNCIHTLTGHQS-LTSGMELKDNILVS-GNADSTVKIWDIKTGQCLQT 462
Score = 57.2 bits (132), Expect = 4e-07
Identities = 47/161 (29%), Positives = 74/161 (45%), Gaps = 9/161 (5%)
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQ 798
+ C+ NR ++SG DD+ + + S V G + L H G V S + ++D NI I+GS
Sbjct: 230 ITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQ-MRD-NIIISGST 285
Query: 799 DGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPL 857
D T+ WN E + T+ + + + V ++ D L + TG LH L
Sbjct: 286 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV--VSGSRDATLRVWDIETGQCLHVL 343
Query: 858 KRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
H A V+ CV +D RV G D + ++ + L T
Sbjct: 344 MGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHT 382
Score = 46.0 bits (104), Expect = 0.001
Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 7/122 (5%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R+ L G H+V ++W + + + +HT GH L + + L++G+ D
Sbjct: 389 RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDNILVSGNAD 446
Query: 716 TSVIVWDLHT---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVT 772
++V +WD+ T L +H + V C+ N++ VI+ DD V + L G +
Sbjct: 447 STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQ--FNKNFVITSSDDGTVKLWDLKTGEFIR 504
Query: 773 KL 774
L
Sbjct: 505 NL 506
>AF411972-1|AAL06291.1| 627|Homo sapiens archipelago beta form
protein.
Length = 627
Score = 103 bits (247), Expect = 5e-21
Identities = 76/288 (26%), Positives = 133/288 (46%), Gaps = 22/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+CL+ G SG ++VW T + TL GH G + N +++SGS
Sbjct: 304 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN--IIISGST 359
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
DRT+ VW T GH+S ++ + + +R +S R + VW +++G LH
Sbjct: 360 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVL 417
Query: 1089 TGPSASID-VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVS-HAERITCFALTADS 1146
G A++ V + + V D V++W +E ++ H R+ ++L D
Sbjct: 418 MGHVAAVRCVQYDGRRVVSGAYDFMVKVWD----PETETCLHTLQGHTNRV--YSLQFDG 471
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
HVV+GS+D S++VW ++ G L GH + + + + +VSG+ D + +WDI
Sbjct: 472 IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL---KDNILVSGNADSTVKIWDI 528
Query: 1207 NT---XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
T VTC++ + ++ ++D T+ +W+ K G
Sbjct: 529 KTGQCLQTLQGPNKHQSAVTCLQF--NKNFVITSSDDGTVKLWDLKTG 574
Score = 92.3 bits (219), Expect = 1e-17
Identities = 70/264 (26%), Positives = 121/264 (45%), Gaps = 16/264 (6%)
Query: 993 WQLSTHRLQATLNGHIGH-ITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
W+ + L GH H ITC+ F N ++SGS+D T+ VW T GH+
Sbjct: 285 WRRGELKSPKVLKGHDDHVITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTG 342
Query: 1052 AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLSDGD 1110
+ + M + + S+DR + VW ++G +H+ G ++++ + L+ K V D
Sbjct: 343 GVWSSQMRDNIIISGSTDRT--LKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRD 400
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
++R+W + G + + H + C + D + VV+G+ D +KVW +
Sbjct: 401 ATLRVWDIETG---QCLHVLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLH 455
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
L GH++ V + + VVSGS D ++ VWD+ T + +++ +
Sbjct: 456 TLQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN 512
Query: 1231 GTIAVSCAEDKTLIIWETKRGLAL 1254
I VS D T+ IW+ K G L
Sbjct: 513 --ILVSGNADSTVKIWDIKTGQCL 534
Score = 85.8 bits (203), Expect = 1e-15
Identities = 54/192 (28%), Positives = 92/192 (47%), Gaps = 7/192 (3%)
Query: 983 SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
SG +RVW + T + L GH+ + CV + V+SG+ D V VW +
Sbjct: 396 SGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKVWDPETETC 453
Query: 1043 SLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG-PSASIDVTLNM 1101
T +GH++ + +L DG +S ++ VW V++G +H+ TG S + + L
Sbjct: 454 LHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD 511
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
V + D++V+IW + G + + H +TC L + V+T S D ++K+W
Sbjct: 512 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTC--LQFNKNFVITSSDDGTVKLW 569
Query: 1162 KLDGGKLSQVLV 1173
L G+ + LV
Sbjct: 570 DLKTGEFIRNLV 581
Score = 77.8 bits (183), Expect = 3e-13
Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 12/230 (5%)
Query: 1035 WQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSAS 1094
W+ + KGH + T L G R +S + VW +G L + G +
Sbjct: 285 WRRGELKSPKVLKGHDDHVITCLQFC-GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGG 343
Query: 1095 IDVTLNMKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGS 1153
+ + ++S D ++++W+ G E H + C L + VV+GS
Sbjct: 344 VWSSQMRDNIIISGSTDRTLKVWNAETG---ECIHTLYGHTSTVRCMHL--HEKRVVSGS 398
Query: 1154 MDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXX 1213
D +L+VW ++ G+ VL+GH V CV + +VVSG++D + VWD T
Sbjct: 399 RDATLRVWDIETGQCLHVLMGHVAAVRCVQY---DGRRVVSGAYDFMVKVWDPETETCLH 455
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPL 1263
+V ++ DG VS + D ++ +W+ + G + + + H L
Sbjct: 456 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSL 503
Score = 72.1 bits (169), Expect = 1e-11
Identities = 54/222 (24%), Positives = 103/222 (46%), Gaps = 8/222 (3%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W+ + +HT GH+ ++ CM + + +++GS D ++ VWD+ T ++ H+
Sbjct: 364 KVWNAETGECIHTLYGHTSTVRCMHL--HEKRVVSGSRDATLRVWDIETGQCLHVLMGHV 421
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A V CV R V+SG D V + + L H V S++ DG ++G
Sbjct: 422 AAVRCVQYDGRR--VVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSG 477
Query: 797 SQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
S D ++ W+VE + T+T + DN+ L++ D+ + + TG L
Sbjct: 478 SLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQT 536
Query: 857 LK-RHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
L+ +K + C+ + + V D + L+ L + + +R
Sbjct: 537 LQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIR 578
Score = 64.5 bits (150), Expect = 3e-09
Identities = 52/236 (22%), Positives = 107/236 (45%), Gaps = 11/236 (4%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
G +V ++W ++ + T GH+G + + +++GS D ++ VW+
Sbjct: 311 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM--RDNIIISGSTDRTLKVWNA 368
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTS 783
T + H + V C+ ++ V+SG D+ + + + G + L G V +
Sbjct: 369 ETGECIHTLYGHTSTVRCMH--LHEKRVVSGSRDATLRVWDIETGQCLHVL---MGHVAA 423
Query: 784 VKVIQ-DGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNE 842
V+ +Q DG ++G+ D V W+ E T L T+ G ++ + D + +++ D
Sbjct: 424 VRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTL-QGHTNRVYSLQFDGIHVVSGSLDTS 482
Query: 843 LHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ + TG +H L H++ + D+ V+ G AD + ++ + + Q L+T
Sbjct: 483 IRVWDVETGNCIHTLTGHQS-LTSGMELKDNILVS-GNADSTVKIWDIKTGQCLQT 536
Score = 57.2 bits (132), Expect = 4e-07
Identities = 47/161 (29%), Positives = 74/161 (45%), Gaps = 9/161 (5%)
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQ 798
+ C+ NR ++SG DD+ + + S V G + L H G V S + ++D NI I+GS
Sbjct: 304 ITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQ-MRD-NIIISGST 359
Query: 799 DGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPL 857
D T+ WN E + T+ + + + V ++ D L + TG LH L
Sbjct: 360 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV--VSGSRDATLRVWDIETGQCLHVL 417
Query: 858 KRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
H A V+ CV +D RV G D + ++ + L T
Sbjct: 418 MGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHT 456
Score = 46.0 bits (104), Expect = 0.001
Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 7/122 (5%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R+ L G H+V ++W + + + +HT GH L + + L++G+ D
Sbjct: 463 RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDNILVSGNAD 520
Query: 716 TSVIVWDLHT---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVT 772
++V +WD+ T L +H + V C+ N++ VI+ DD V + L G +
Sbjct: 521 STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQ--FNKNFVITSSDDGTVKLWDLKTGEFIR 578
Query: 773 KL 774
L
Sbjct: 579 NL 580
>AF411971-1|AAL06290.1| 707|Homo sapiens archipelago alpha form
protein.
Length = 707
Score = 103 bits (247), Expect = 5e-21
Identities = 76/288 (26%), Positives = 133/288 (46%), Gaps = 22/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+CL+ G SG ++VW T + TL GH G + N +++SGS
Sbjct: 384 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN--IIISGST 439
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
DRT+ VW T GH+S ++ + + +R +S R + VW +++G LH
Sbjct: 440 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVL 497
Query: 1089 TGPSASID-VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVS-HAERITCFALTADS 1146
G A++ V + + V D V++W +E ++ H R+ ++L D
Sbjct: 498 MGHVAAVRCVQYDGRRVVSGAYDFMVKVWD----PETETCLHTLQGHTNRV--YSLQFDG 551
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
HVV+GS+D S++VW ++ G L GH + + + + +VSG+ D + +WDI
Sbjct: 552 IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL---KDNILVSGNADSTVKIWDI 608
Query: 1207 NT---XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
T VTC++ + ++ ++D T+ +W+ K G
Sbjct: 609 KTGQCLQTLQGPNKHQSAVTCLQF--NKNFVITSSDDGTVKLWDLKTG 654
Score = 92.3 bits (219), Expect = 1e-17
Identities = 70/264 (26%), Positives = 121/264 (45%), Gaps = 16/264 (6%)
Query: 993 WQLSTHRLQATLNGHIGH-ITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
W+ + L GH H ITC+ F N ++SGS+D T+ VW T GH+
Sbjct: 365 WRRGELKSPKVLKGHDDHVITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTG 422
Query: 1052 AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLSDGD 1110
+ + M + + S+DR + VW ++G +H+ G ++++ + L+ K V D
Sbjct: 423 GVWSSQMRDNIIISGSTDRT--LKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRD 480
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
++R+W + G + + H + C + D + VV+G+ D +KVW +
Sbjct: 481 ATLRVWDIETG---QCLHVLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLH 535
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
L GH++ V + + VVSGS D ++ VWD+ T + +++ +
Sbjct: 536 TLQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN 592
Query: 1231 GTIAVSCAEDKTLIIWETKRGLAL 1254
I VS D T+ IW+ K G L
Sbjct: 593 --ILVSGNADSTVKIWDIKTGQCL 614
Score = 85.8 bits (203), Expect = 1e-15
Identities = 54/192 (28%), Positives = 92/192 (47%), Gaps = 7/192 (3%)
Query: 983 SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
SG +RVW + T + L GH+ + CV + V+SG+ D V VW +
Sbjct: 476 SGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKVWDPETETC 533
Query: 1043 SLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG-PSASIDVTLNM 1101
T +GH++ + +L DG +S ++ VW V++G +H+ TG S + + L
Sbjct: 534 LHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD 591
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
V + D++V+IW + G + + H +TC L + V+T S D ++K+W
Sbjct: 592 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTC--LQFNKNFVITSSDDGTVKLW 649
Query: 1162 KLDGGKLSQVLV 1173
L G+ + LV
Sbjct: 650 DLKTGEFIRNLV 661
Score = 77.8 bits (183), Expect = 3e-13
Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 12/230 (5%)
Query: 1035 WQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSAS 1094
W+ + KGH + T L G R +S + VW +G L + G +
Sbjct: 365 WRRGELKSPKVLKGHDDHVITCLQFC-GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGG 423
Query: 1095 IDVTLNMKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGS 1153
+ + ++S D ++++W+ G E H + C L + VV+GS
Sbjct: 424 VWSSQMRDNIIISGSTDRTLKVWNAETG---ECIHTLYGHTSTVRCMHL--HEKRVVSGS 478
Query: 1154 MDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXX 1213
D +L+VW ++ G+ VL+GH V CV + +VVSG++D + VWD T
Sbjct: 479 RDATLRVWDIETGQCLHVLMGHVAAVRCVQY---DGRRVVSGAYDFMVKVWDPETETCLH 535
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPL 1263
+V ++ DG VS + D ++ +W+ + G + + + H L
Sbjct: 536 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSL 583
Score = 72.1 bits (169), Expect = 1e-11
Identities = 54/222 (24%), Positives = 103/222 (46%), Gaps = 8/222 (3%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W+ + +HT GH+ ++ CM + + +++GS D ++ VWD+ T ++ H+
Sbjct: 444 KVWNAETGECIHTLYGHTSTVRCMHL--HEKRVVSGSRDATLRVWDIETGQCLHVLMGHV 501
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A V CV R V+SG D V + + L H V S++ DG ++G
Sbjct: 502 AAVRCVQYDGRR--VVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSG 557
Query: 797 SQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
S D ++ W+VE + T+T + DN+ L++ D+ + + TG L
Sbjct: 558 SLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQT 616
Query: 857 LK-RHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
L+ +K + C+ + + V D + L+ L + + +R
Sbjct: 617 LQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIR 658
Score = 64.5 bits (150), Expect = 3e-09
Identities = 52/236 (22%), Positives = 107/236 (45%), Gaps = 11/236 (4%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
G +V ++W ++ + T GH+G + + +++GS D ++ VW+
Sbjct: 391 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM--RDNIIISGSTDRTLKVWNA 448
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTS 783
T + H + V C+ ++ V+SG D+ + + + G + L G V +
Sbjct: 449 ETGECIHTLYGHTSTVRCMH--LHEKRVVSGSRDATLRVWDIETGQCLHVL---MGHVAA 503
Query: 784 VKVIQ-DGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNE 842
V+ +Q DG ++G+ D V W+ E T L T+ G ++ + D + +++ D
Sbjct: 504 VRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTL-QGHTNRVYSLQFDGIHVVSGSLDTS 562
Query: 843 LHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ + TG +H L H++ + D+ V+ G AD + ++ + + Q L+T
Sbjct: 563 IRVWDVETGNCIHTLTGHQS-LTSGMELKDNILVS-GNADSTVKIWDIKTGQCLQT 616
Score = 57.2 bits (132), Expect = 4e-07
Identities = 47/161 (29%), Positives = 74/161 (45%), Gaps = 9/161 (5%)
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQ 798
+ C+ NR ++SG DD+ + + S V G + L H G V S + ++D NI I+GS
Sbjct: 384 ITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQ-MRD-NIIISGST 439
Query: 799 DGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPL 857
D T+ WN E + T+ + + + V ++ D L + TG LH L
Sbjct: 440 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV--VSGSRDATLRVWDIETGQCLHVL 497
Query: 858 KRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
H A V+ CV +D RV G D + ++ + L T
Sbjct: 498 MGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHT 536
Score = 46.0 bits (104), Expect = 0.001
Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 7/122 (5%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R+ L G H+V ++W + + + +HT GH L + + L++G+ D
Sbjct: 543 RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDNILVSGNAD 600
Query: 716 TSVIVWDLHT---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVT 772
++V +WD+ T L +H + V C+ N++ VI+ DD V + L G +
Sbjct: 601 STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQ--FNKNFVITSSDDGTVKLWDLKTGEFIR 658
Query: 773 KL 774
L
Sbjct: 659 NL 660
>AF383178-1|AAK60269.1| 561|Homo sapiens F-box protein FBX30 protein.
Length = 561
Score = 103 bits (247), Expect = 5e-21
Identities = 76/288 (26%), Positives = 133/288 (46%), Gaps = 22/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+CL+ G SG ++VW T + TL GH G + N +++SGS
Sbjct: 238 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN--IIISGST 293
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
DRT+ VW T GH+S ++ + + +R +S R + VW +++G LH
Sbjct: 294 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVL 351
Query: 1089 TGPSASID-VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVS-HAERITCFALTADS 1146
G A++ V + + V D V++W +E ++ H R+ ++L D
Sbjct: 352 MGHVAAVRCVQYDGRRVVSGAYDFMVKVWD----PETETCLHTLQGHTNRV--YSLQFDG 405
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
HVV+GS+D S++VW ++ G L GH + + + + +VSG+ D + +WDI
Sbjct: 406 IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL---KDNILVSGNADSTVKIWDI 462
Query: 1207 NT---XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
T VTC++ + ++ ++D T+ +W+ K G
Sbjct: 463 KTGQCLQTLQGPNKHQSAVTCLQF--NKNFVITSSDDGTVKLWDLKTG 508
Score = 92.3 bits (219), Expect = 1e-17
Identities = 70/264 (26%), Positives = 121/264 (45%), Gaps = 16/264 (6%)
Query: 993 WQLSTHRLQATLNGHIGH-ITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
W+ + L GH H ITC+ F N ++SGS+D T+ VW T GH+
Sbjct: 219 WRRGELKSPKVLKGHDDHVITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTG 276
Query: 1052 AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLSDGD 1110
+ + M + + S+DR + VW ++G +H+ G ++++ + L+ K V D
Sbjct: 277 GVWSSQMRDNIIISGSTDRT--LKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRD 334
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
++R+W + G + + H + C + D + VV+G+ D +KVW +
Sbjct: 335 ATLRVWDIETG---QCLHVLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLH 389
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
L GH++ V + + VVSGS D ++ VWD+ T + +++ +
Sbjct: 390 TLQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN 446
Query: 1231 GTIAVSCAEDKTLIIWETKRGLAL 1254
I VS D T+ IW+ K G L
Sbjct: 447 --ILVSGNADSTVKIWDIKTGQCL 468
Score = 85.8 bits (203), Expect = 1e-15
Identities = 54/192 (28%), Positives = 92/192 (47%), Gaps = 7/192 (3%)
Query: 983 SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
SG +RVW + T + L GH+ + CV + V+SG+ D V VW +
Sbjct: 330 SGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKVWDPETETC 387
Query: 1043 SLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG-PSASIDVTLNM 1101
T +GH++ + +L DG +S ++ VW V++G +H+ TG S + + L
Sbjct: 388 LHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD 445
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
V + D++V+IW + G + + H +TC L + V+T S D ++K+W
Sbjct: 446 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTC--LQFNKNFVITSSDDGTVKLW 503
Query: 1162 KLDGGKLSQVLV 1173
L G+ + LV
Sbjct: 504 DLKTGEFIRNLV 515
Score = 77.8 bits (183), Expect = 3e-13
Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 12/230 (5%)
Query: 1035 WQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSAS 1094
W+ + KGH + T L G R +S + VW +G L + G +
Sbjct: 219 WRRGELKSPKVLKGHDDHVITCLQFC-GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGG 277
Query: 1095 IDVTLNMKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGS 1153
+ + ++S D ++++W+ G E H + C L + VV+GS
Sbjct: 278 VWSSQMRDNIIISGSTDRTLKVWNAETG---ECIHTLYGHTSTVRCMHL--HEKRVVSGS 332
Query: 1154 MDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXX 1213
D +L+VW ++ G+ VL+GH V CV + +VVSG++D + VWD T
Sbjct: 333 RDATLRVWDIETGQCLHVLMGHVAAVRCVQY---DGRRVVSGAYDFMVKVWDPETETCLH 389
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPL 1263
+V ++ DG VS + D ++ +W+ + G + + + H L
Sbjct: 390 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSL 437
Score = 72.1 bits (169), Expect = 1e-11
Identities = 54/222 (24%), Positives = 103/222 (46%), Gaps = 8/222 (3%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W+ + +HT GH+ ++ CM + + +++GS D ++ VWD+ T ++ H+
Sbjct: 298 KVWNAETGECIHTLYGHTSTVRCMHL--HEKRVVSGSRDATLRVWDIETGQCLHVLMGHV 355
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A V CV R V+SG D V + + L H V S++ DG ++G
Sbjct: 356 AAVRCVQYDGRR--VVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSG 411
Query: 797 SQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
S D ++ W+VE + T+T + DN+ L++ D+ + + TG L
Sbjct: 412 SLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQT 470
Query: 857 LK-RHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
L+ +K + C+ + + V D + L+ L + + +R
Sbjct: 471 LQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIR 512
Score = 64.5 bits (150), Expect = 3e-09
Identities = 52/236 (22%), Positives = 107/236 (45%), Gaps = 11/236 (4%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
G +V ++W ++ + T GH+G + + +++GS D ++ VW+
Sbjct: 245 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM--RDNIIISGSTDRTLKVWNA 302
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTS 783
T + H + V C+ ++ V+SG D+ + + + G + L G V +
Sbjct: 303 ETGECIHTLYGHTSTVRCMH--LHEKRVVSGSRDATLRVWDIETGQCLHVL---MGHVAA 357
Query: 784 VKVIQ-DGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNE 842
V+ +Q DG ++G+ D V W+ E T L T+ G ++ + D + +++ D
Sbjct: 358 VRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTL-QGHTNRVYSLQFDGIHVVSGSLDTS 416
Query: 843 LHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ + TG +H L H++ + D+ V+ G AD + ++ + + Q L+T
Sbjct: 417 IRVWDVETGNCIHTLTGHQS-LTSGMELKDNILVS-GNADSTVKIWDIKTGQCLQT 470
Score = 57.2 bits (132), Expect = 4e-07
Identities = 47/161 (29%), Positives = 74/161 (45%), Gaps = 9/161 (5%)
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQ 798
+ C+ NR ++SG DD+ + + S V G + L H G V S + ++D NI I+GS
Sbjct: 238 ITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQ-MRD-NIIISGST 293
Query: 799 DGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPL 857
D T+ WN E + T+ + + + V ++ D L + TG LH L
Sbjct: 294 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV--VSGSRDATLRVWDIETGQCLHVL 351
Query: 858 KRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
H A V+ CV +D RV G D + ++ + L T
Sbjct: 352 MGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHT 390
Score = 46.0 bits (104), Expect = 0.001
Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 7/122 (5%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R+ L G H+V ++W + + + +HT GH L + + L++G+ D
Sbjct: 397 RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDNILVSGNAD 454
Query: 716 TSVIVWDLHT---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVT 772
++V +WD+ T L +H + V C+ N++ VI+ DD V + L G +
Sbjct: 455 STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQ--FNKNFVITSSDDGTVKLWDLKTGEFIR 512
Query: 773 KL 774
L
Sbjct: 513 NL 514
>AB209725-1|BAD92962.1| 624|Homo sapiens F-box protein FBW7 isoform 2
variant protein.
Length = 624
Score = 103 bits (247), Expect = 5e-21
Identities = 76/288 (26%), Positives = 133/288 (46%), Gaps = 22/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+CL+ G SG ++VW T + TL GH G + N +++SGS
Sbjct: 301 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN--IIISGST 356
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
DRT+ VW T GH+S ++ + + +R +S R + VW +++G LH
Sbjct: 357 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVL 414
Query: 1089 TGPSASID-VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVS-HAERITCFALTADS 1146
G A++ V + + V D V++W +E ++ H R+ ++L D
Sbjct: 415 MGHVAAVRCVQYDGRRVVSGAYDFMVKVWD----PETETCLHTLQGHTNRV--YSLQFDG 468
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
HVV+GS+D S++VW ++ G L GH + + + + +VSG+ D + +WDI
Sbjct: 469 IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL---KDNILVSGNADSTVKIWDI 525
Query: 1207 NT---XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
T VTC++ + ++ ++D T+ +W+ K G
Sbjct: 526 KTGQCLQTLQGPNKHQSAVTCLQF--NKNFVITSSDDGTVKLWDLKTG 571
Score = 92.3 bits (219), Expect = 1e-17
Identities = 70/264 (26%), Positives = 121/264 (45%), Gaps = 16/264 (6%)
Query: 993 WQLSTHRLQATLNGHIGH-ITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
W+ + L GH H ITC+ F N ++SGS+D T+ VW T GH+
Sbjct: 282 WRRGELKSPKVLKGHDDHVITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTG 339
Query: 1052 AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLSDGD 1110
+ + M + + S+DR + VW ++G +H+ G ++++ + L+ K V D
Sbjct: 340 GVWSSQMRDNIIISGSTDRT--LKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRD 397
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
++R+W + G + + H + C + D + VV+G+ D +KVW +
Sbjct: 398 ATLRVWDIETG---QCLHVLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLH 452
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
L GH++ V + + VVSGS D ++ VWD+ T + +++ +
Sbjct: 453 TLQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN 509
Query: 1231 GTIAVSCAEDKTLIIWETKRGLAL 1254
I VS D T+ IW+ K G L
Sbjct: 510 --ILVSGNADSTVKIWDIKTGQCL 531
Score = 85.8 bits (203), Expect = 1e-15
Identities = 54/192 (28%), Positives = 92/192 (47%), Gaps = 7/192 (3%)
Query: 983 SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
SG +RVW + T + L GH+ + CV + V+SG+ D V VW +
Sbjct: 393 SGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKVWDPETETC 450
Query: 1043 SLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG-PSASIDVTLNM 1101
T +GH++ + +L DG +S ++ VW V++G +H+ TG S + + L
Sbjct: 451 LHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD 508
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
V + D++V+IW + G + + H +TC L + V+T S D ++K+W
Sbjct: 509 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTC--LQFNKNFVITSSDDGTVKLW 566
Query: 1162 KLDGGKLSQVLV 1173
L G+ + LV
Sbjct: 567 DLKTGEFIRNLV 578
Score = 77.8 bits (183), Expect = 3e-13
Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 12/230 (5%)
Query: 1035 WQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSAS 1094
W+ + KGH + T L G R +S + VW +G L + G +
Sbjct: 282 WRRGELKSPKVLKGHDDHVITCLQFC-GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGG 340
Query: 1095 IDVTLNMKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGS 1153
+ + ++S D ++++W+ G E H + C L + VV+GS
Sbjct: 341 VWSSQMRDNIIISGSTDRTLKVWNAETG---ECIHTLYGHTSTVRCMHL--HEKRVVSGS 395
Query: 1154 MDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXX 1213
D +L+VW ++ G+ VL+GH V CV + +VVSG++D + VWD T
Sbjct: 396 RDATLRVWDIETGQCLHVLMGHVAAVRCVQY---DGRRVVSGAYDFMVKVWDPETETCLH 452
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPL 1263
+V ++ DG VS + D ++ +W+ + G + + + H L
Sbjct: 453 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSL 500
Score = 72.1 bits (169), Expect = 1e-11
Identities = 54/222 (24%), Positives = 103/222 (46%), Gaps = 8/222 (3%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W+ + +HT GH+ ++ CM + + +++GS D ++ VWD+ T ++ H+
Sbjct: 361 KVWNAETGECIHTLYGHTSTVRCMHL--HEKRVVSGSRDATLRVWDIETGQCLHVLMGHV 418
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A V CV R V+SG D V + + L H V S++ DG ++G
Sbjct: 419 AAVRCVQYDGRR--VVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSG 474
Query: 797 SQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
S D ++ W+VE + T+T + DN+ L++ D+ + + TG L
Sbjct: 475 SLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQT 533
Query: 857 LK-RHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
L+ +K + C+ + + V D + L+ L + + +R
Sbjct: 534 LQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIR 575
Score = 64.5 bits (150), Expect = 3e-09
Identities = 52/236 (22%), Positives = 107/236 (45%), Gaps = 11/236 (4%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
G +V ++W ++ + T GH+G + + +++GS D ++ VW+
Sbjct: 308 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM--RDNIIISGSTDRTLKVWNA 365
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTS 783
T + H + V C+ ++ V+SG D+ + + + G + L G V +
Sbjct: 366 ETGECIHTLYGHTSTVRCMH--LHEKRVVSGSRDATLRVWDIETGQCLHVL---MGHVAA 420
Query: 784 VKVIQ-DGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNE 842
V+ +Q DG ++G+ D V W+ E T L T+ G ++ + D + +++ D
Sbjct: 421 VRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTL-QGHTNRVYSLQFDGIHVVSGSLDTS 479
Query: 843 LHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ + TG +H L H++ + D+ V+ G AD + ++ + + Q L+T
Sbjct: 480 IRVWDVETGNCIHTLTGHQS-LTSGMELKDNILVS-GNADSTVKIWDIKTGQCLQT 533
Score = 57.2 bits (132), Expect = 4e-07
Identities = 47/161 (29%), Positives = 74/161 (45%), Gaps = 9/161 (5%)
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQ 798
+ C+ NR ++SG DD+ + + S V G + L H G V S + ++D NI I+GS
Sbjct: 301 ITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQ-MRD-NIIISGST 356
Query: 799 DGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPL 857
D T+ WN E + T+ + + + V ++ D L + TG LH L
Sbjct: 357 DRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV--VSGSRDATLRVWDIETGQCLHVL 414
Query: 858 KRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
H A V+ CV +D RV G D + ++ + L T
Sbjct: 415 MGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHT 453
Score = 46.0 bits (104), Expect = 0.001
Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 7/122 (5%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R+ L G H+V ++W + + + +HT GH L + + L++G+ D
Sbjct: 460 RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDNILVSGNAD 517
Query: 716 TSVIVWDLHT---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVT 772
++V +WD+ T L +H + V C+ N++ VI+ DD V + L G +
Sbjct: 518 STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQ--FNKNFVITSSDDGTVKLWDLKTGEFIR 575
Query: 773 KL 774
L
Sbjct: 576 NL 577
>BC026213-1|AAH26213.1| 529|Homo sapiens F-box and WD repeat domain
containing 11 protein.
Length = 529
Score = 102 bits (245), Expect = 8e-21
Identities = 80/304 (26%), Positives = 141/304 (46%), Gaps = 25/304 (8%)
Query: 955 NITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCV 1014
N+ +Q + + CL+ D + SG +++W ++ L GH G + C+
Sbjct: 216 NLQRIQCRSENSKGVYCLQY--DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCL 273
Query: 1015 TFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNV 1074
+ ++++GS D TV VW + T H+ A+ L S+G S + R++
Sbjct: 274 QYDER--VIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHL-RFSNGLMVTCS-KDRSI 329
Query: 1075 HVWLVDSG--IVLHSA-TGPSASIDVT-LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
VW + S I L G A+++V + KY V + GD ++++WS + E R
Sbjct: 330 AVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTS---TCEFVRTL 386
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKT 1190
H I C L + VV+GS D ++++W ++ G +VL GH ++V C + NK
Sbjct: 387 NGHKRGIAC--LQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC--IRFDNK- 441
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTG-------DGTIAVSCAEDKTL 1243
++VSG++D + VWD+ T V+ +G D +S + D T+
Sbjct: 442 RIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTI 501
Query: 1244 IIWE 1247
+IW+
Sbjct: 502 LIWD 505
Score = 72.1 bits (169), Expect = 1e-11
Identities = 57/219 (26%), Positives = 100/219 (45%), Gaps = 10/219 (4%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W S + GH+GS+LC+ + + ++TGS D++V VWD++T V ++ H
Sbjct: 250 KIWDKTSLECLKVLTGHTGSVLCL--QYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHN 307
Query: 737 APVLCVAAIVNRSLVISGGDDSAVI--ITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
VL + N +V D S + + S D L L HR +V V D +
Sbjct: 308 EAVLHL-RFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF--DDKYIV 364
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYL 854
+ S D T+ W+ + T+ G I + + +++ DN + L G L
Sbjct: 365 SASGDRTIKVWSTSTCEFVRTLN-GHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACL 423
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSA 893
L+ H+ V+ C+ D+ R+ G D +I ++ L +A
Sbjct: 424 RVLEGHEELVR--CIRFDNKRIVSGAYDGKIKVWDLQAA 460
Score = 70.9 bits (166), Expect = 3e-11
Identities = 44/199 (22%), Positives = 92/199 (46%), Gaps = 8/199 (4%)
Query: 701 CVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAV 760
C+ + + +++G D S+ +WD +L + H VLC+ + ++++G DS V
Sbjct: 232 CLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQ--YDERVIVTGSSDSTV 289
Query: 761 IITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT--LLSTVTA 818
+ + G ++ L HH +V ++ + +T S+D ++ W++ + T L V
Sbjct: 290 RVWDVNTGEVLNTLIHHNEAVLHLRF--SNGLMVTCSKDRSIAVWDMASATDITLRRVLV 347
Query: 819 GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAV 878
G + V D+ ++++ GD + + + T ++ L HK + C+ + V
Sbjct: 348 GHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIA--CLQYRDRLVVS 405
Query: 879 GCADQRIYLYSLHSAQLLR 897
G +D I L+ + LR
Sbjct: 406 GSSDNTIRLWDIECGACLR 424
Score = 56.4 bits (130), Expect = 7e-07
Identities = 28/116 (24%), Positives = 58/116 (50%), Gaps = 5/116 (4%)
Query: 1140 FALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDC 1199
+ L D + +++G D S+K+W + +VL GH+ V C+ ++ +V+GS D
Sbjct: 231 YCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY---DERVIVTGSSDS 287
Query: 1200 NLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALT 1255
+ VWD+NT V ++ + + V+C++D+++ +W+ +T
Sbjct: 288 TVRVWDVNTGEVLNTLIHHNEAVLHLRFSNG--LMVTCSKDRSIAVWDMASATDIT 341
Score = 54.0 bits (124), Expect = 4e-06
Identities = 52/208 (25%), Positives = 87/208 (41%), Gaps = 14/208 (6%)
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDGDNSVRIWSLA 1119
D + +S R ++ +W S L TG + S+ + + + V D++VR+W +
Sbjct: 236 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVN 295
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK---LSQVLVGHS 1176
G E + H E + L + +VT S D S+ VW + L +VLVGH
Sbjct: 296 TG---EVLNTLIHHNEAV--LHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHR 350
Query: 1177 DIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVS 1236
V V +K +VS S D + VW +T + C++ + VS
Sbjct: 351 AAVN--VVDFDDK-YIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVS 405
Query: 1237 CAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+ D T+ +W+ + G L H L+
Sbjct: 406 GSSDNTIRLWDIECGACLRVLEGHEELV 433
Score = 36.3 bits (80), Expect = 0.81
Identities = 33/154 (21%), Positives = 61/154 (39%), Gaps = 15/154 (9%)
Query: 665 QHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLH 724
+++V A ++W + V T GH I C+ + +++GS D ++ +WD+
Sbjct: 361 KYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACL--QYRDRLVVSGSSDNTIRLWDIE 418
Query: 725 TLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL---------VDGALVTKLD 775
A + H V C+ + ++SG D + + L + L
Sbjct: 419 CGACLRVLEGHEELVRCIR--FDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLV 476
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
H G V ++ D I+ S D T+ W+ N
Sbjct: 477 EHSGRVFRLQF--DEFQIISSSHDDTILIWDFLN 508
>AF176022-1|AAF04528.1| 542|Homo sapiens F-box protein Fbw1b protein.
Length = 542
Score = 102 bits (245), Expect = 8e-21
Identities = 80/304 (26%), Positives = 141/304 (46%), Gaps = 25/304 (8%)
Query: 955 NITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCV 1014
N+ +Q + + CL+ D + SG +++W ++ L GH G + C+
Sbjct: 229 NLQRIQCRSENSKGVYCLQY--DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCL 286
Query: 1015 TFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNV 1074
+ ++++GS D TV VW + T H+ A+ L S+G S + R++
Sbjct: 287 QYDER--VIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHL-RFSNGLMVTCS-KDRSI 342
Query: 1075 HVWLVDSG--IVLHSA-TGPSASIDVT-LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
VW + S I L G A+++V + KY V + GD ++++WS + E R
Sbjct: 343 AVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTS---TCEFVRTL 399
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKT 1190
H I C L + VV+GS D ++++W ++ G +VL GH ++V C + NK
Sbjct: 400 NGHKRGIAC--LQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC--IRFDNK- 454
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTG-------DGTIAVSCAEDKTL 1243
++VSG++D + VWD+ T V+ +G D +S + D T+
Sbjct: 455 RIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTI 514
Query: 1244 IIWE 1247
+IW+
Sbjct: 515 LIWD 518
Score = 72.1 bits (169), Expect = 1e-11
Identities = 57/219 (26%), Positives = 100/219 (45%), Gaps = 10/219 (4%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W S + GH+GS+LC+ + + ++TGS D++V VWD++T V ++ H
Sbjct: 263 KIWDKTSLECLKVLTGHTGSVLCL--QYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHN 320
Query: 737 APVLCVAAIVNRSLVISGGDDSAVI--ITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
VL + N +V D S + + S D L L HR +V V D +
Sbjct: 321 EAVLHL-RFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF--DDKYIV 377
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYL 854
+ S D T+ W+ + T+ G I + + +++ DN + L G L
Sbjct: 378 SASGDRTIKVWSTSTCEFVRTLN-GHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACL 436
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSA 893
L+ H+ V+ C+ D+ R+ G D +I ++ L +A
Sbjct: 437 RVLEGHEELVR--CIRFDNKRIVSGAYDGKIKVWDLQAA 473
Score = 70.9 bits (166), Expect = 3e-11
Identities = 44/199 (22%), Positives = 92/199 (46%), Gaps = 8/199 (4%)
Query: 701 CVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAV 760
C+ + + +++G D S+ +WD +L + H VLC+ + ++++G DS V
Sbjct: 245 CLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQ--YDERVIVTGSSDSTV 302
Query: 761 IITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT--LLSTVTA 818
+ + G ++ L HH +V ++ + +T S+D ++ W++ + T L V
Sbjct: 303 RVWDVNTGEVLNTLIHHNEAVLHLRF--SNGLMVTCSKDRSIAVWDMASATDITLRRVLV 360
Query: 819 GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAV 878
G + V D+ ++++ GD + + + T ++ L HK + C+ + V
Sbjct: 361 GHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIA--CLQYRDRLVVS 418
Query: 879 GCADQRIYLYSLHSAQLLR 897
G +D I L+ + LR
Sbjct: 419 GSSDNTIRLWDIECGACLR 437
Score = 56.4 bits (130), Expect = 7e-07
Identities = 28/116 (24%), Positives = 58/116 (50%), Gaps = 5/116 (4%)
Query: 1140 FALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDC 1199
+ L D + +++G D S+K+W + +VL GH+ V C+ ++ +V+GS D
Sbjct: 244 YCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY---DERVIVTGSSDS 300
Query: 1200 NLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALT 1255
+ VWD+NT V ++ + + V+C++D+++ +W+ +T
Sbjct: 301 TVRVWDVNTGEVLNTLIHHNEAVLHLRFSNG--LMVTCSKDRSIAVWDMASATDIT 354
Score = 54.0 bits (124), Expect = 4e-06
Identities = 52/208 (25%), Positives = 87/208 (41%), Gaps = 14/208 (6%)
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDGDNSVRIWSLA 1119
D + +S R ++ +W S L TG + S+ + + + V D++VR+W +
Sbjct: 249 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVN 308
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK---LSQVLVGHS 1176
G E + H E + L + +VT S D S+ VW + L +VLVGH
Sbjct: 309 TG---EVLNTLIHHNEAV--LHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHR 363
Query: 1177 DIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVS 1236
V V +K +VS S D + VW +T + C++ + VS
Sbjct: 364 AAVN--VVDFDDK-YIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVS 418
Query: 1237 CAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+ D T+ +W+ + G L H L+
Sbjct: 419 GSSDNTIRLWDIECGACLRVLEGHEELV 446
Score = 36.3 bits (80), Expect = 0.81
Identities = 33/154 (21%), Positives = 61/154 (39%), Gaps = 15/154 (9%)
Query: 665 QHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLH 724
+++V A ++W + V T GH I C+ + +++GS D ++ +WD+
Sbjct: 374 KYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACL--QYRDRLVVSGSSDNTIRLWDIE 431
Query: 725 TLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL---------VDGALVTKLD 775
A + H V C+ + ++SG D + + L + L
Sbjct: 432 CGACLRVLEGHEELVRCIR--FDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLV 489
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
H G V ++ D I+ S D T+ W+ N
Sbjct: 490 EHSGRVFRLQF--DEFQIISSSHDDTILIWDFLN 521
>AB033281-1|BAA92331.1| 542|Homo sapiens F-box and WD-repeats protein
beta-TRCP2 isoform C protein.
Length = 542
Score = 102 bits (245), Expect = 8e-21
Identities = 80/304 (26%), Positives = 141/304 (46%), Gaps = 25/304 (8%)
Query: 955 NITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCV 1014
N+ +Q + + CL+ D + SG +++W ++ L GH G + C+
Sbjct: 229 NLQRIQCRSENSKGVYCLQY--DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCL 286
Query: 1015 TFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNV 1074
+ ++++GS D TV VW + T H+ A+ L S+G S + R++
Sbjct: 287 QYDER--VIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHL-RFSNGLMVTCS-KDRSI 342
Query: 1075 HVWLVDSG--IVLHSA-TGPSASIDVT-LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
VW + S I L G A+++V + KY V + GD ++++WS + E R
Sbjct: 343 AVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTS---TCEFVRTL 399
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKT 1190
H I C L + VV+GS D ++++W ++ G +VL GH ++V C + NK
Sbjct: 400 NGHKRGIAC--LQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC--IRFDNK- 454
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTG-------DGTIAVSCAEDKTL 1243
++VSG++D + VWD+ T V+ +G D +S + D T+
Sbjct: 455 RIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTI 514
Query: 1244 IIWE 1247
+IW+
Sbjct: 515 LIWD 518
Score = 72.1 bits (169), Expect = 1e-11
Identities = 57/219 (26%), Positives = 100/219 (45%), Gaps = 10/219 (4%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W S + GH+GS+LC+ + + ++TGS D++V VWD++T V ++ H
Sbjct: 263 KIWDKTSLECLKVLTGHTGSVLCL--QYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHN 320
Query: 737 APVLCVAAIVNRSLVISGGDDSAVI--ITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
VL + N +V D S + + S D L L HR +V V D +
Sbjct: 321 EAVLHL-RFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF--DDKYIV 377
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYL 854
+ S D T+ W+ + T+ G I + + +++ DN + L G L
Sbjct: 378 SASGDRTIKVWSTSTCEFVRTLN-GHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACL 436
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSA 893
L+ H+ V+ C+ D+ R+ G D +I ++ L +A
Sbjct: 437 RVLEGHEELVR--CIRFDNKRIVSGAYDGKIKVWDLQAA 473
Score = 70.9 bits (166), Expect = 3e-11
Identities = 44/199 (22%), Positives = 92/199 (46%), Gaps = 8/199 (4%)
Query: 701 CVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAV 760
C+ + + +++G D S+ +WD +L + H VLC+ + ++++G DS V
Sbjct: 245 CLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQ--YDERVIVTGSSDSTV 302
Query: 761 IITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT--LLSTVTA 818
+ + G ++ L HH +V ++ + +T S+D ++ W++ + T L V
Sbjct: 303 RVWDVNTGEVLNTLIHHNEAVLHLRF--SNGLMVTCSKDRSIAVWDMASATDITLRRVLV 360
Query: 819 GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAV 878
G + V D+ ++++ GD + + + T ++ L HK + C+ + V
Sbjct: 361 GHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIA--CLQYRDRLVVS 418
Query: 879 GCADQRIYLYSLHSAQLLR 897
G +D I L+ + LR
Sbjct: 419 GSSDNTIRLWDIECGACLR 437
Score = 56.4 bits (130), Expect = 7e-07
Identities = 28/116 (24%), Positives = 58/116 (50%), Gaps = 5/116 (4%)
Query: 1140 FALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDC 1199
+ L D + +++G D S+K+W + +VL GH+ V C+ ++ +V+GS D
Sbjct: 244 YCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY---DERVIVTGSSDS 300
Query: 1200 NLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALT 1255
+ VWD+NT V ++ + + V+C++D+++ +W+ +T
Sbjct: 301 TVRVWDVNTGEVLNTLIHHNEAVLHLRFSNG--LMVTCSKDRSIAVWDMASATDIT 354
Score = 54.0 bits (124), Expect = 4e-06
Identities = 52/208 (25%), Positives = 87/208 (41%), Gaps = 14/208 (6%)
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDGDNSVRIWSLA 1119
D + +S R ++ +W S L TG + S+ + + + V D++VR+W +
Sbjct: 249 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVN 308
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK---LSQVLVGHS 1176
G E + H E + L + +VT S D S+ VW + L +VLVGH
Sbjct: 309 TG---EVLNTLIHHNEAV--LHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHR 363
Query: 1177 DIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVS 1236
V V +K +VS S D + VW +T + C++ + VS
Sbjct: 364 AAVN--VVDFDDK-YIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVS 418
Query: 1237 CAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+ D T+ +W+ + G L H L+
Sbjct: 419 GSSDNTIRLWDIECGACLRVLEGHEELV 446
Score = 36.3 bits (80), Expect = 0.81
Identities = 33/154 (21%), Positives = 61/154 (39%), Gaps = 15/154 (9%)
Query: 665 QHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLH 724
+++V A ++W + V T GH I C+ + +++GS D ++ +WD+
Sbjct: 374 KYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACL--QYRDRLVVSGSSDNTIRLWDIE 431
Query: 725 TLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL---------VDGALVTKLD 775
A + H V C+ + ++SG D + + L + L
Sbjct: 432 CGACLRVLEGHEELVRCIR--FDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLV 489
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
H G V ++ D I+ S D T+ W+ N
Sbjct: 490 EHSGRVFRLQF--DEFQIISSSHDDTILIWDFLN 521
>AB033280-1|BAA92330.1| 529|Homo sapiens F-box and WD-repeats protein
beta-TRCP2 isoform B protein.
Length = 529
Score = 102 bits (245), Expect = 8e-21
Identities = 80/304 (26%), Positives = 141/304 (46%), Gaps = 25/304 (8%)
Query: 955 NITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCV 1014
N+ +Q + + CL+ D + SG +++W ++ L GH G + C+
Sbjct: 216 NLQRIQCRSENSKGVYCLQY--DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCL 273
Query: 1015 TFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNV 1074
+ ++++GS D TV VW + T H+ A+ L S+G S + R++
Sbjct: 274 QYDER--VIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHL-RFSNGLMVTCS-KDRSI 329
Query: 1075 HVWLVDSG--IVLHSA-TGPSASIDVT-LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
VW + S I L G A+++V + KY V + GD ++++WS + E R
Sbjct: 330 AVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTS---TCEFVRTL 386
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKT 1190
H I C L + VV+GS D ++++W ++ G +VL GH ++V C + NK
Sbjct: 387 NGHKRGIAC--LQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC--IRFDNK- 441
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTG-------DGTIAVSCAEDKTL 1243
++VSG++D + VWD+ T V+ +G D +S + D T+
Sbjct: 442 RIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTI 501
Query: 1244 IIWE 1247
+IW+
Sbjct: 502 LIWD 505
Score = 72.1 bits (169), Expect = 1e-11
Identities = 57/219 (26%), Positives = 100/219 (45%), Gaps = 10/219 (4%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W S + GH+GS+LC+ + + ++TGS D++V VWD++T V ++ H
Sbjct: 250 KIWDKTSLECLKVLTGHTGSVLCL--QYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHN 307
Query: 737 APVLCVAAIVNRSLVISGGDDSAVI--ITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
VL + N +V D S + + S D L L HR +V V D +
Sbjct: 308 EAVLHL-RFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF--DDKYIV 364
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYL 854
+ S D T+ W+ + T+ G I + + +++ DN + L G L
Sbjct: 365 SASGDRTIKVWSTSTCEFVRTLN-GHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACL 423
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSA 893
L+ H+ V+ C+ D+ R+ G D +I ++ L +A
Sbjct: 424 RVLEGHEELVR--CIRFDNKRIVSGAYDGKIKVWDLQAA 460
Score = 70.9 bits (166), Expect = 3e-11
Identities = 44/199 (22%), Positives = 92/199 (46%), Gaps = 8/199 (4%)
Query: 701 CVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAV 760
C+ + + +++G D S+ +WD +L + H VLC+ + ++++G DS V
Sbjct: 232 CLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQ--YDERVIVTGSSDSTV 289
Query: 761 IITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT--LLSTVTA 818
+ + G ++ L HH +V ++ + +T S+D ++ W++ + T L V
Sbjct: 290 RVWDVNTGEVLNTLIHHNEAVLHLRF--SNGLMVTCSKDRSIAVWDMASATDITLRRVLV 347
Query: 819 GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAV 878
G + V D+ ++++ GD + + + T ++ L HK + C+ + V
Sbjct: 348 GHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIA--CLQYRDRLVVS 405
Query: 879 GCADQRIYLYSLHSAQLLR 897
G +D I L+ + LR
Sbjct: 406 GSSDNTIRLWDIECGACLR 424
Score = 56.4 bits (130), Expect = 7e-07
Identities = 28/116 (24%), Positives = 58/116 (50%), Gaps = 5/116 (4%)
Query: 1140 FALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDC 1199
+ L D + +++G D S+K+W + +VL GH+ V C+ ++ +V+GS D
Sbjct: 231 YCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY---DERVIVTGSSDS 287
Query: 1200 NLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALT 1255
+ VWD+NT V ++ + + V+C++D+++ +W+ +T
Sbjct: 288 TVRVWDVNTGEVLNTLIHHNEAVLHLRFSNG--LMVTCSKDRSIAVWDMASATDIT 341
Score = 54.0 bits (124), Expect = 4e-06
Identities = 52/208 (25%), Positives = 87/208 (41%), Gaps = 14/208 (6%)
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDGDNSVRIWSLA 1119
D + +S R ++ +W S L TG + S+ + + + V D++VR+W +
Sbjct: 236 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVN 295
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK---LSQVLVGHS 1176
G E + H E + L + +VT S D S+ VW + L +VLVGH
Sbjct: 296 TG---EVLNTLIHHNEAV--LHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHR 350
Query: 1177 DIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVS 1236
V V +K +VS S D + VW +T + C++ + VS
Sbjct: 351 AAVN--VVDFDDK-YIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVS 405
Query: 1237 CAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+ D T+ +W+ + G L H L+
Sbjct: 406 GSSDNTIRLWDIECGACLRVLEGHEELV 433
Score = 36.3 bits (80), Expect = 0.81
Identities = 33/154 (21%), Positives = 61/154 (39%), Gaps = 15/154 (9%)
Query: 665 QHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLH 724
+++V A ++W + V T GH I C+ + +++GS D ++ +WD+
Sbjct: 361 KYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACL--QYRDRLVVSGSSDNTIRLWDIE 418
Query: 725 TLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL---------VDGALVTKLD 775
A + H V C+ + ++SG D + + L + L
Sbjct: 419 CGACLRVLEGHEELVRCIR--FDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLV 476
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
H G V ++ D I+ S D T+ W+ N
Sbjct: 477 EHSGRVFRLQF--DEFQIISSSHDDTILIWDFLN 508
>AB033279-1|BAA92329.1| 508|Homo sapiens F-box and WD-repeats protein
beta-TRCP2 isoform A protein.
Length = 508
Score = 102 bits (245), Expect = 8e-21
Identities = 80/304 (26%), Positives = 141/304 (46%), Gaps = 25/304 (8%)
Query: 955 NITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCV 1014
N+ +Q + + CL+ D + SG +++W ++ L GH G + C+
Sbjct: 195 NLQRIQCRSENSKGVYCLQY--DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCL 252
Query: 1015 TFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNV 1074
+ ++++GS D TV VW + T H+ A+ L S+G S + R++
Sbjct: 253 QYDER--VIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHL-RFSNGLMVTCS-KDRSI 308
Query: 1075 HVWLVDSG--IVLHSA-TGPSASIDVT-LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
VW + S I L G A+++V + KY V + GD ++++WS + E R
Sbjct: 309 AVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTS---TCEFVRTL 365
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKT 1190
H I C L + VV+GS D ++++W ++ G +VL GH ++V C + NK
Sbjct: 366 NGHKRGIAC--LQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC--IRFDNK- 420
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTG-------DGTIAVSCAEDKTL 1243
++VSG++D + VWD+ T V+ +G D +S + D T+
Sbjct: 421 RIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTI 480
Query: 1244 IIWE 1247
+IW+
Sbjct: 481 LIWD 484
Score = 72.1 bits (169), Expect = 1e-11
Identities = 57/219 (26%), Positives = 100/219 (45%), Gaps = 10/219 (4%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W S + GH+GS+LC+ + + ++TGS D++V VWD++T V ++ H
Sbjct: 229 KIWDKTSLECLKVLTGHTGSVLCL--QYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHN 286
Query: 737 APVLCVAAIVNRSLVISGGDDSAVI--ITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
VL + N +V D S + + S D L L HR +V V D +
Sbjct: 287 EAVLHL-RFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF--DDKYIV 343
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYL 854
+ S D T+ W+ + T+ G I + + +++ DN + L G L
Sbjct: 344 SASGDRTIKVWSTSTCEFVRTLN-GHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACL 402
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSA 893
L+ H+ V+ C+ D+ R+ G D +I ++ L +A
Sbjct: 403 RVLEGHEELVR--CIRFDNKRIVSGAYDGKIKVWDLQAA 439
Score = 70.9 bits (166), Expect = 3e-11
Identities = 44/199 (22%), Positives = 92/199 (46%), Gaps = 8/199 (4%)
Query: 701 CVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAV 760
C+ + + +++G D S+ +WD +L + H VLC+ + ++++G DS V
Sbjct: 211 CLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQ--YDERVIVTGSSDSTV 268
Query: 761 IITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT--LLSTVTA 818
+ + G ++ L HH +V ++ + +T S+D ++ W++ + T L V
Sbjct: 269 RVWDVNTGEVLNTLIHHNEAVLHLRF--SNGLMVTCSKDRSIAVWDMASATDITLRRVLV 326
Query: 819 GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAV 878
G + V D+ ++++ GD + + + T ++ L HK + C+ + V
Sbjct: 327 GHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIA--CLQYRDRLVVS 384
Query: 879 GCADQRIYLYSLHSAQLLR 897
G +D I L+ + LR
Sbjct: 385 GSSDNTIRLWDIECGACLR 403
Score = 56.4 bits (130), Expect = 7e-07
Identities = 28/116 (24%), Positives = 58/116 (50%), Gaps = 5/116 (4%)
Query: 1140 FALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDC 1199
+ L D + +++G D S+K+W + +VL GH+ V C+ ++ +V+GS D
Sbjct: 210 YCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY---DERVIVTGSSDS 266
Query: 1200 NLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALT 1255
+ VWD+NT V ++ + + V+C++D+++ +W+ +T
Sbjct: 267 TVRVWDVNTGEVLNTLIHHNEAVLHLRFSNG--LMVTCSKDRSIAVWDMASATDIT 320
Score = 54.0 bits (124), Expect = 4e-06
Identities = 52/208 (25%), Positives = 87/208 (41%), Gaps = 14/208 (6%)
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDGDNSVRIWSLA 1119
D + +S R ++ +W S L TG + S+ + + + V D++VR+W +
Sbjct: 215 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVN 274
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK---LSQVLVGHS 1176
G E + H E + L + +VT S D S+ VW + L +VLVGH
Sbjct: 275 TG---EVLNTLIHHNEAV--LHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHR 329
Query: 1177 DIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVS 1236
V V +K +VS S D + VW +T + C++ + VS
Sbjct: 330 AAVN--VVDFDDK-YIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVS 384
Query: 1237 CAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+ D T+ +W+ + G L H L+
Sbjct: 385 GSSDNTIRLWDIECGACLRVLEGHEELV 412
Score = 36.3 bits (80), Expect = 0.81
Identities = 33/154 (21%), Positives = 61/154 (39%), Gaps = 15/154 (9%)
Query: 665 QHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLH 724
+++V A ++W + V T GH I C+ + +++GS D ++ +WD+
Sbjct: 340 KYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACL--QYRDRLVVSGSSDNTIRLWDIE 397
Query: 725 TLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL---------VDGALVTKLD 775
A + H V C+ + ++SG D + + L + L
Sbjct: 398 CGACLRVLEGHEELVRCIR--FDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLV 455
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
H G V ++ D I+ S D T+ W+ N
Sbjct: 456 EHSGRVFRLQF--DEFQIISSSHDDTILIWDFLN 487
>AB014596-1|BAA31671.1| 550|Homo sapiens KIAA0696 protein protein.
Length = 550
Score = 102 bits (245), Expect = 8e-21
Identities = 80/304 (26%), Positives = 141/304 (46%), Gaps = 25/304 (8%)
Query: 955 NITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCV 1014
N+ +Q + + CL+ D + SG +++W ++ L GH G + C+
Sbjct: 237 NLQRIQCRSENSKGVYCLQY--DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCL 294
Query: 1015 TFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNV 1074
+ ++++GS D TV VW + T H+ A+ L S+G S + R++
Sbjct: 295 QYDER--VIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHL-RFSNGLMVTCS-KDRSI 350
Query: 1075 HVWLVDSG--IVLHSA-TGPSASIDVT-LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
VW + S I L G A+++V + KY V + GD ++++WS + E R
Sbjct: 351 AVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTS---TCEFVRTL 407
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKT 1190
H I C L + VV+GS D ++++W ++ G +VL GH ++V C + NK
Sbjct: 408 NGHKRGIAC--LQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC--IRFDNK- 462
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTG-------DGTIAVSCAEDKTL 1243
++VSG++D + VWD+ T V+ +G D +S + D T+
Sbjct: 463 RIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTI 522
Query: 1244 IIWE 1247
+IW+
Sbjct: 523 LIWD 526
Score = 72.1 bits (169), Expect = 1e-11
Identities = 57/219 (26%), Positives = 100/219 (45%), Gaps = 10/219 (4%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W S + GH+GS+LC+ + + ++TGS D++V VWD++T V ++ H
Sbjct: 271 KIWDKTSLECLKVLTGHTGSVLCL--QYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHN 328
Query: 737 APVLCVAAIVNRSLVISGGDDSAVI--ITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
VL + N +V D S + + S D L L HR +V V D +
Sbjct: 329 EAVLHL-RFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF--DDKYIV 385
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYL 854
+ S D T+ W+ + T+ G I + + +++ DN + L G L
Sbjct: 386 SASGDRTIKVWSTSTCEFVRTLN-GHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACL 444
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSA 893
L+ H+ V+ C+ D+ R+ G D +I ++ L +A
Sbjct: 445 RVLEGHEELVR--CIRFDNKRIVSGAYDGKIKVWDLQAA 481
Score = 70.9 bits (166), Expect = 3e-11
Identities = 44/199 (22%), Positives = 92/199 (46%), Gaps = 8/199 (4%)
Query: 701 CVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAV 760
C+ + + +++G D S+ +WD +L + H VLC+ + ++++G DS V
Sbjct: 253 CLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQ--YDERVIVTGSSDSTV 310
Query: 761 IITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT--LLSTVTA 818
+ + G ++ L HH +V ++ + +T S+D ++ W++ + T L V
Sbjct: 311 RVWDVNTGEVLNTLIHHNEAVLHLRF--SNGLMVTCSKDRSIAVWDMASATDITLRRVLV 368
Query: 819 GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAV 878
G + V D+ ++++ GD + + + T ++ L HK + C+ + V
Sbjct: 369 GHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIA--CLQYRDRLVVS 426
Query: 879 GCADQRIYLYSLHSAQLLR 897
G +D I L+ + LR
Sbjct: 427 GSSDNTIRLWDIECGACLR 445
Score = 56.4 bits (130), Expect = 7e-07
Identities = 28/116 (24%), Positives = 58/116 (50%), Gaps = 5/116 (4%)
Query: 1140 FALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDC 1199
+ L D + +++G D S+K+W + +VL GH+ V C+ ++ +V+GS D
Sbjct: 252 YCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY---DERVIVTGSSDS 308
Query: 1200 NLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALT 1255
+ VWD+NT V ++ + + V+C++D+++ +W+ +T
Sbjct: 309 TVRVWDVNTGEVLNTLIHHNEAVLHLRFSNG--LMVTCSKDRSIAVWDMASATDIT 362
Score = 54.0 bits (124), Expect = 4e-06
Identities = 52/208 (25%), Positives = 87/208 (41%), Gaps = 14/208 (6%)
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDGDNSVRIWSLA 1119
D + +S R ++ +W S L TG + S+ + + + V D++VR+W +
Sbjct: 257 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVN 316
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK---LSQVLVGHS 1176
G E + H E + L + +VT S D S+ VW + L +VLVGH
Sbjct: 317 TG---EVLNTLIHHNEAV--LHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHR 371
Query: 1177 DIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVS 1236
V V +K +VS S D + VW +T + C++ + VS
Sbjct: 372 AAVN--VVDFDDK-YIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVS 426
Query: 1237 CAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+ D T+ +W+ + G L H L+
Sbjct: 427 GSSDNTIRLWDIECGACLRVLEGHEELV 454
Score = 36.3 bits (80), Expect = 0.81
Identities = 33/154 (21%), Positives = 61/154 (39%), Gaps = 15/154 (9%)
Query: 665 QHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLH 724
+++V A ++W + V T GH I C+ + +++GS D ++ +WD+
Sbjct: 382 KYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACL--QYRDRLVVSGSSDNTIRLWDIE 439
Query: 725 TLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL---------VDGALVTKLD 775
A + H V C+ + ++SG D + + L + L
Sbjct: 440 CGACLRVLEGHEELVRCIR--FDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLV 497
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
H G V ++ D I+ S D T+ W+ N
Sbjct: 498 EHSGRVFRLQF--DEFQIISSSHDDTILIWDFLN 529
>Y14153-1|CAA74572.1| 569|Homo sapiens beta-transducin repeats
containing protein protein.
Length = 569
Score = 101 bits (241), Expect = 3e-20
Identities = 77/288 (26%), Positives = 131/288 (45%), Gaps = 21/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ CL+ D Q SG +++W +T + L GH G + C+ + ++++GS
Sbjct: 270 VYCLQY--DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDER--VIITGSS 325
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D TV VW + T H A+ L + S DR+ V + I L
Sbjct: 326 DSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRV 385
Query: 1089 -TGPSASIDVT-LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
G A+++V + KY V + GD ++++W+ + E R H I C L
Sbjct: 386 LVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTS---TCEFVRTLNGHKRGIAC--LQYRD 440
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+ VV+GS D ++++W ++ G +VL GH ++V C + NK ++VSG++D + VWD+
Sbjct: 441 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC--IRFDNK-RIVSGAYDGKIKVWDL 497
Query: 1207 NTXXXXXXXXXXXXKVTCVKVTG-------DGTIAVSCAEDKTLIIWE 1247
T V+ +G D VS + D T++IW+
Sbjct: 498 VAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWD 545
Score = 74.1 bits (174), Expect = 3e-12
Identities = 47/199 (23%), Positives = 94/199 (47%), Gaps = 8/199 (4%)
Query: 701 CVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAV 760
C+ + Q +++G D ++ +WD +TL K + H VLC+ + ++I+G DS V
Sbjct: 272 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQ--YDERVIITGSSDSTV 329
Query: 761 IITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT--LLSTVTA 818
+ + G ++ L HH +V ++ + + +T S+D ++ W++ + T L V
Sbjct: 330 RVWDVNTGEMLNTLIHHCEAVLHLRF--NNGMMVTCSKDRSIAVWDMASPTDITLRRVLV 387
Query: 819 GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAV 878
G + V D+ ++++ GD + + T ++ L HK + C+ + V
Sbjct: 388 GHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA--CLQYRDRLVVS 445
Query: 879 GCADQRIYLYSLHSAQLLR 897
G +D I L+ + LR
Sbjct: 446 GSSDNTIRLWDIECGACLR 464
Score = 70.5 bits (165), Expect = 4e-11
Identities = 53/205 (25%), Positives = 97/205 (47%), Gaps = 12/205 (5%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+GS+LC+ + + ++TGS D++V VWD++T + ++ H VL + N ++
Sbjct: 305 GHTGSVLCL--QYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLR--FNNGMM 360
Query: 752 ISGGDDSAVII---TSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
++ D ++ + S D L L HR +V V D ++ S D T+ WN
Sbjct: 361 VTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWNTS 418
Query: 809 NFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFC 868
+ T+ G I + + +++ DN + L G L L+ H+ V+ C
Sbjct: 419 TCEFVRTLN-GHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVR--C 475
Query: 869 VAHDSSRVAVGCADQRIYLYSLHSA 893
+ D+ R+ G D +I ++ L +A
Sbjct: 476 IRFDNKRIVSGAYDGKIKVWDLVAA 500
Score = 52.4 bits (120), Expect = 1e-05
Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 14/208 (6%)
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDGDNSVRIWSLA 1119
D ++ +S R + +W ++ TG + S+ + + + + D++VR+W +
Sbjct: 276 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVN 335
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK---LSQVLVGHS 1176
G E + H E + L ++ +VT S D S+ VW + L +VLVGH
Sbjct: 336 TG---EMLNTLIHHCEAV--LHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHR 390
Query: 1177 DIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVS 1236
V V +K +VS S D + VW+ +T + C++ + VS
Sbjct: 391 AAVN--VVDFDDK-YIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRD--RLVVS 445
Query: 1237 CAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+ D T+ +W+ + G L H L+
Sbjct: 446 GSSDNTIRLWDIECGACLRVLEGHEELV 473
Score = 39.9 bits (89), Expect = 0.066
Identities = 35/154 (22%), Positives = 65/154 (42%), Gaps = 15/154 (9%)
Query: 665 QHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLH 724
+++V A ++W+ + V T GH I C+ + +++GS D ++ +WD+
Sbjct: 401 KYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACL--QYRDRLVVSGSSDNTIRLWDIE 458
Query: 725 TLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLV--------DGALVTK-LD 775
A + H V C+ + ++SG D + + LV G L + L
Sbjct: 459 CGACLRVLEGHEELVRCIR--FDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLV 516
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
H G V ++ D ++ S D T+ W+ N
Sbjct: 517 EHSGRVFRLQF--DEFQIVSSSHDDTILIWDFLN 548
>BC027994-1|AAH27994.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 101 bits (241), Expect = 3e-20
Identities = 77/288 (26%), Positives = 131/288 (45%), Gaps = 21/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ CL+ D Q SG +++W +T + L GH G + C+ + ++++GS
Sbjct: 306 VYCLQY--DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDER--VIITGSS 361
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D TV VW + T H A+ L + S DR+ V + I L
Sbjct: 362 DSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRV 421
Query: 1089 -TGPSASIDVT-LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
G A+++V + KY V + GD ++++W+ + E R H I C L
Sbjct: 422 LVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTS---TCEFVRTLNGHKRGIAC--LQYRD 476
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+ VV+GS D ++++W ++ G +VL GH ++V C + NK ++VSG++D + VWD+
Sbjct: 477 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC--IRFDNK-RIVSGAYDGKIKVWDL 533
Query: 1207 NTXXXXXXXXXXXXKVTCVKVTG-------DGTIAVSCAEDKTLIIWE 1247
T V+ +G D VS + D T++IW+
Sbjct: 534 VAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWD 581
Score = 74.1 bits (174), Expect = 3e-12
Identities = 47/199 (23%), Positives = 94/199 (47%), Gaps = 8/199 (4%)
Query: 701 CVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAV 760
C+ + Q +++G D ++ +WD +TL K + H VLC+ + ++I+G DS V
Sbjct: 308 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQ--YDERVIITGSSDSTV 365
Query: 761 IITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT--LLSTVTA 818
+ + G ++ L HH +V ++ + + +T S+D ++ W++ + T L V
Sbjct: 366 RVWDVNTGEMLNTLIHHCEAVLHLRF--NNGMMVTCSKDRSIAVWDMASPTDITLRRVLV 423
Query: 819 GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAV 878
G + V D+ ++++ GD + + T ++ L HK + C+ + V
Sbjct: 424 GHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA--CLQYRDRLVVS 481
Query: 879 GCADQRIYLYSLHSAQLLR 897
G +D I L+ + LR
Sbjct: 482 GSSDNTIRLWDIECGACLR 500
Score = 70.5 bits (165), Expect = 4e-11
Identities = 53/205 (25%), Positives = 97/205 (47%), Gaps = 12/205 (5%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+GS+LC+ + + ++TGS D++V VWD++T + ++ H VL + N ++
Sbjct: 341 GHTGSVLCL--QYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLR--FNNGMM 396
Query: 752 ISGGDDSAVII---TSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
++ D ++ + S D L L HR +V V D ++ S D T+ WN
Sbjct: 397 VTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWNTS 454
Query: 809 NFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFC 868
+ T+ G I + + +++ DN + L G L L+ H+ V+ C
Sbjct: 455 TCEFVRTLN-GHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVR--C 511
Query: 869 VAHDSSRVAVGCADQRIYLYSLHSA 893
+ D+ R+ G D +I ++ L +A
Sbjct: 512 IRFDNKRIVSGAYDGKIKVWDLVAA 536
Score = 52.4 bits (120), Expect = 1e-05
Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 14/208 (6%)
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDGDNSVRIWSLA 1119
D ++ +S R + +W ++ TG + S+ + + + + D++VR+W +
Sbjct: 312 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVN 371
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK---LSQVLVGHS 1176
G E + H E + L ++ +VT S D S+ VW + L +VLVGH
Sbjct: 372 TG---EMLNTLIHHCEAV--LHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHR 426
Query: 1177 DIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVS 1236
V V +K +VS S D + VW+ +T + C++ + VS
Sbjct: 427 AAVN--VVDFDDK-YIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRD--RLVVS 481
Query: 1237 CAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+ D T+ +W+ + G L H L+
Sbjct: 482 GSSDNTIRLWDIECGACLRVLEGHEELV 509
Score = 39.9 bits (89), Expect = 0.066
Identities = 35/154 (22%), Positives = 65/154 (42%), Gaps = 15/154 (9%)
Query: 665 QHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLH 724
+++V A ++W+ + V T GH I C+ + +++GS D ++ +WD+
Sbjct: 437 KYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACL--QYRDRLVVSGSSDNTIRLWDIE 494
Query: 725 TLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLV--------DGALVTK-LD 775
A + H V C+ + ++SG D + + LV G L + L
Sbjct: 495 CGACLRVLEGHEELVRCIR--FDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLV 552
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
H G V ++ D ++ S D T+ W+ N
Sbjct: 553 EHSGRVFRLQF--DEFQIVSSSHDDTILIWDFLN 584
>AL627424-18|CAI41043.1| 569|Homo sapiens beta-transducin repeat
containing protein.
Length = 569
Score = 101 bits (241), Expect = 3e-20
Identities = 77/288 (26%), Positives = 131/288 (45%), Gaps = 21/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ CL+ D Q SG +++W +T + L GH G + C+ + ++++GS
Sbjct: 270 VYCLQY--DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDER--VIITGSS 325
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D TV VW + T H A+ L + S DR+ V + I L
Sbjct: 326 DSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRV 385
Query: 1089 -TGPSASIDVT-LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
G A+++V + KY V + GD ++++W+ + E R H I C L
Sbjct: 386 LVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTS---TCEFVRTLNGHKRGIAC--LQYRD 440
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+ VV+GS D ++++W ++ G +VL GH ++V C + NK ++VSG++D + VWD+
Sbjct: 441 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC--IRFDNK-RIVSGAYDGKIKVWDL 497
Query: 1207 NTXXXXXXXXXXXXKVTCVKVTG-------DGTIAVSCAEDKTLIIWE 1247
T V+ +G D VS + D T++IW+
Sbjct: 498 VAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWD 545
Score = 74.1 bits (174), Expect = 3e-12
Identities = 47/199 (23%), Positives = 94/199 (47%), Gaps = 8/199 (4%)
Query: 701 CVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAV 760
C+ + Q +++G D ++ +WD +TL K + H VLC+ + ++I+G DS V
Sbjct: 272 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQ--YDERVIITGSSDSTV 329
Query: 761 IITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT--LLSTVTA 818
+ + G ++ L HH +V ++ + + +T S+D ++ W++ + T L V
Sbjct: 330 RVWDVNTGEMLNTLIHHCEAVLHLRF--NNGMMVTCSKDRSIAVWDMASPTDITLRRVLV 387
Query: 819 GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAV 878
G + V D+ ++++ GD + + T ++ L HK + C+ + V
Sbjct: 388 GHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA--CLQYRDRLVVS 445
Query: 879 GCADQRIYLYSLHSAQLLR 897
G +D I L+ + LR
Sbjct: 446 GSSDNTIRLWDIECGACLR 464
Score = 70.5 bits (165), Expect = 4e-11
Identities = 53/205 (25%), Positives = 97/205 (47%), Gaps = 12/205 (5%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+GS+LC+ + + ++TGS D++V VWD++T + ++ H VL + N ++
Sbjct: 305 GHTGSVLCL--QYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLR--FNNGMM 360
Query: 752 ISGGDDSAVII---TSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
++ D ++ + S D L L HR +V V D ++ S D T+ WN
Sbjct: 361 VTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWNTS 418
Query: 809 NFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFC 868
+ T+ G I + + +++ DN + L G L L+ H+ V+ C
Sbjct: 419 TCEFVRTLN-GHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVR--C 475
Query: 869 VAHDSSRVAVGCADQRIYLYSLHSA 893
+ D+ R+ G D +I ++ L +A
Sbjct: 476 IRFDNKRIVSGAYDGKIKVWDLVAA 500
Score = 52.4 bits (120), Expect = 1e-05
Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 14/208 (6%)
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDGDNSVRIWSLA 1119
D ++ +S R + +W ++ TG + S+ + + + + D++VR+W +
Sbjct: 276 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVN 335
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK---LSQVLVGHS 1176
G E + H E + L ++ +VT S D S+ VW + L +VLVGH
Sbjct: 336 TG---EMLNTLIHHCEAV--LHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHR 390
Query: 1177 DIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVS 1236
V V +K +VS S D + VW+ +T + C++ + VS
Sbjct: 391 AAVN--VVDFDDK-YIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRD--RLVVS 445
Query: 1237 CAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+ D T+ +W+ + G L H L+
Sbjct: 446 GSSDNTIRLWDIECGACLRVLEGHEELV 473
Score = 39.9 bits (89), Expect = 0.066
Identities = 35/154 (22%), Positives = 65/154 (42%), Gaps = 15/154 (9%)
Query: 665 QHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLH 724
+++V A ++W+ + V T GH I C+ + +++GS D ++ +WD+
Sbjct: 401 KYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACL--QYRDRLVVSGSSDNTIRLWDIE 458
Query: 725 TLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLV--------DGALVTK-LD 775
A + H V C+ + ++SG D + + LV G L + L
Sbjct: 459 CGACLRVLEGHEELVRCIR--FDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLV 516
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
H G V ++ D ++ S D T+ W+ N
Sbjct: 517 EHSGRVFRLQF--DEFQIVSSSHDDTILIWDFLN 548
>AL627424-17|CAI41042.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 101 bits (241), Expect = 3e-20
Identities = 77/288 (26%), Positives = 131/288 (45%), Gaps = 21/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ CL+ D Q SG +++W +T + L GH G + C+ + ++++GS
Sbjct: 306 VYCLQY--DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDER--VIITGSS 361
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D TV VW + T H A+ L + S DR+ V + I L
Sbjct: 362 DSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRV 421
Query: 1089 -TGPSASIDVT-LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
G A+++V + KY V + GD ++++W+ + E R H I C L
Sbjct: 422 LVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTS---TCEFVRTLNGHKRGIAC--LQYRD 476
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+ VV+GS D ++++W ++ G +VL GH ++V C + NK ++VSG++D + VWD+
Sbjct: 477 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC--IRFDNK-RIVSGAYDGKIKVWDL 533
Query: 1207 NTXXXXXXXXXXXXKVTCVKVTG-------DGTIAVSCAEDKTLIIWE 1247
T V+ +G D VS + D T++IW+
Sbjct: 534 VAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWD 581
Score = 74.1 bits (174), Expect = 3e-12
Identities = 47/199 (23%), Positives = 94/199 (47%), Gaps = 8/199 (4%)
Query: 701 CVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAV 760
C+ + Q +++G D ++ +WD +TL K + H VLC+ + ++I+G DS V
Sbjct: 308 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQ--YDERVIITGSSDSTV 365
Query: 761 IITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT--LLSTVTA 818
+ + G ++ L HH +V ++ + + +T S+D ++ W++ + T L V
Sbjct: 366 RVWDVNTGEMLNTLIHHCEAVLHLRF--NNGMMVTCSKDRSIAVWDMASPTDITLRRVLV 423
Query: 819 GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAV 878
G + V D+ ++++ GD + + T ++ L HK + C+ + V
Sbjct: 424 GHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA--CLQYRDRLVVS 481
Query: 879 GCADQRIYLYSLHSAQLLR 897
G +D I L+ + LR
Sbjct: 482 GSSDNTIRLWDIECGACLR 500
Score = 70.5 bits (165), Expect = 4e-11
Identities = 53/205 (25%), Positives = 97/205 (47%), Gaps = 12/205 (5%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+GS+LC+ + + ++TGS D++V VWD++T + ++ H VL + N ++
Sbjct: 341 GHTGSVLCL--QYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLR--FNNGMM 396
Query: 752 ISGGDDSAVII---TSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
++ D ++ + S D L L HR +V V D ++ S D T+ WN
Sbjct: 397 VTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWNTS 454
Query: 809 NFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFC 868
+ T+ G I + + +++ DN + L G L L+ H+ V+ C
Sbjct: 455 TCEFVRTLN-GHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVR--C 511
Query: 869 VAHDSSRVAVGCADQRIYLYSLHSA 893
+ D+ R+ G D +I ++ L +A
Sbjct: 512 IRFDNKRIVSGAYDGKIKVWDLVAA 536
Score = 52.4 bits (120), Expect = 1e-05
Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 14/208 (6%)
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDGDNSVRIWSLA 1119
D ++ +S R + +W ++ TG + S+ + + + + D++VR+W +
Sbjct: 312 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVN 371
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK---LSQVLVGHS 1176
G E + H E + L ++ +VT S D S+ VW + L +VLVGH
Sbjct: 372 TG---EMLNTLIHHCEAV--LHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHR 426
Query: 1177 DIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVS 1236
V V +K +VS S D + VW+ +T + C++ + VS
Sbjct: 427 AAVN--VVDFDDK-YIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRD--RLVVS 481
Query: 1237 CAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+ D T+ +W+ + G L H L+
Sbjct: 482 GSSDNTIRLWDIECGACLRVLEGHEELV 509
Score = 39.9 bits (89), Expect = 0.066
Identities = 35/154 (22%), Positives = 65/154 (42%), Gaps = 15/154 (9%)
Query: 665 QHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLH 724
+++V A ++W+ + V T GH I C+ + +++GS D ++ +WD+
Sbjct: 437 KYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACL--QYRDRLVVSGSSDNTIRLWDIE 494
Query: 725 TLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLV--------DGALVTK-LD 775
A + H V C+ + ++SG D + + LV G L + L
Sbjct: 495 CGACLRVLEGHEELVRCIR--FDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLV 552
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
H G V ++ D ++ S D T+ W+ N
Sbjct: 553 EHSGRVFRLQF--DEFQIVSSSHDDTILIWDFLN 584
>AL445463-3|CAI12964.1| 569|Homo sapiens beta-transducin repeat
containing protein.
Length = 569
Score = 101 bits (241), Expect = 3e-20
Identities = 77/288 (26%), Positives = 131/288 (45%), Gaps = 21/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ CL+ D Q SG +++W +T + L GH G + C+ + ++++GS
Sbjct: 270 VYCLQY--DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDER--VIITGSS 325
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D TV VW + T H A+ L + S DR+ V + I L
Sbjct: 326 DSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRV 385
Query: 1089 -TGPSASIDVT-LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
G A+++V + KY V + GD ++++W+ + E R H I C L
Sbjct: 386 LVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTS---TCEFVRTLNGHKRGIAC--LQYRD 440
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+ VV+GS D ++++W ++ G +VL GH ++V C + NK ++VSG++D + VWD+
Sbjct: 441 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC--IRFDNK-RIVSGAYDGKIKVWDL 497
Query: 1207 NTXXXXXXXXXXXXKVTCVKVTG-------DGTIAVSCAEDKTLIIWE 1247
T V+ +G D VS + D T++IW+
Sbjct: 498 VAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWD 545
Score = 74.1 bits (174), Expect = 3e-12
Identities = 47/199 (23%), Positives = 94/199 (47%), Gaps = 8/199 (4%)
Query: 701 CVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAV 760
C+ + Q +++G D ++ +WD +TL K + H VLC+ + ++I+G DS V
Sbjct: 272 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQ--YDERVIITGSSDSTV 329
Query: 761 IITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT--LLSTVTA 818
+ + G ++ L HH +V ++ + + +T S+D ++ W++ + T L V
Sbjct: 330 RVWDVNTGEMLNTLIHHCEAVLHLRF--NNGMMVTCSKDRSIAVWDMASPTDITLRRVLV 387
Query: 819 GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAV 878
G + V D+ ++++ GD + + T ++ L HK + C+ + V
Sbjct: 388 GHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA--CLQYRDRLVVS 445
Query: 879 GCADQRIYLYSLHSAQLLR 897
G +D I L+ + LR
Sbjct: 446 GSSDNTIRLWDIECGACLR 464
Score = 70.5 bits (165), Expect = 4e-11
Identities = 53/205 (25%), Positives = 97/205 (47%), Gaps = 12/205 (5%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+GS+LC+ + + ++TGS D++V VWD++T + ++ H VL + N ++
Sbjct: 305 GHTGSVLCL--QYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLR--FNNGMM 360
Query: 752 ISGGDDSAVII---TSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
++ D ++ + S D L L HR +V V D ++ S D T+ WN
Sbjct: 361 VTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWNTS 418
Query: 809 NFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFC 868
+ T+ G I + + +++ DN + L G L L+ H+ V+ C
Sbjct: 419 TCEFVRTLN-GHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVR--C 475
Query: 869 VAHDSSRVAVGCADQRIYLYSLHSA 893
+ D+ R+ G D +I ++ L +A
Sbjct: 476 IRFDNKRIVSGAYDGKIKVWDLVAA 500
Score = 52.4 bits (120), Expect = 1e-05
Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 14/208 (6%)
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDGDNSVRIWSLA 1119
D ++ +S R + +W ++ TG + S+ + + + + D++VR+W +
Sbjct: 276 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVN 335
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK---LSQVLVGHS 1176
G E + H E + L ++ +VT S D S+ VW + L +VLVGH
Sbjct: 336 TG---EMLNTLIHHCEAV--LHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHR 390
Query: 1177 DIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVS 1236
V V +K +VS S D + VW+ +T + C++ + VS
Sbjct: 391 AAVN--VVDFDDK-YIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRD--RLVVS 445
Query: 1237 CAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+ D T+ +W+ + G L H L+
Sbjct: 446 GSSDNTIRLWDIECGACLRVLEGHEELV 473
Score = 39.9 bits (89), Expect = 0.066
Identities = 35/154 (22%), Positives = 65/154 (42%), Gaps = 15/154 (9%)
Query: 665 QHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLH 724
+++V A ++W+ + V T GH I C+ + +++GS D ++ +WD+
Sbjct: 401 KYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACL--QYRDRLVVSGSSDNTIRLWDIE 458
Query: 725 TLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLV--------DGALVTK-LD 775
A + H V C+ + ++SG D + + LV G L + L
Sbjct: 459 CGACLRVLEGHEELVRCIR--FDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLV 516
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
H G V ++ D ++ S D T+ W+ N
Sbjct: 517 EHSGRVFRLQF--DEFQIVSSSHDDTILIWDFLN 548
>AL445463-2|CAI12963.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 101 bits (241), Expect = 3e-20
Identities = 77/288 (26%), Positives = 131/288 (45%), Gaps = 21/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ CL+ D Q SG +++W +T + L GH G + C+ + ++++GS
Sbjct: 306 VYCLQY--DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDER--VIITGSS 361
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D TV VW + T H A+ L + S DR+ V + I L
Sbjct: 362 DSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRV 421
Query: 1089 -TGPSASIDVT-LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
G A+++V + KY V + GD ++++W+ + E R H I C L
Sbjct: 422 LVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTS---TCEFVRTLNGHKRGIAC--LQYRD 476
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+ VV+GS D ++++W ++ G +VL GH ++V C + NK ++VSG++D + VWD+
Sbjct: 477 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC--IRFDNK-RIVSGAYDGKIKVWDL 533
Query: 1207 NTXXXXXXXXXXXXKVTCVKVTG-------DGTIAVSCAEDKTLIIWE 1247
T V+ +G D VS + D T++IW+
Sbjct: 534 VAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWD 581
Score = 74.1 bits (174), Expect = 3e-12
Identities = 47/199 (23%), Positives = 94/199 (47%), Gaps = 8/199 (4%)
Query: 701 CVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAV 760
C+ + Q +++G D ++ +WD +TL K + H VLC+ + ++I+G DS V
Sbjct: 308 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQ--YDERVIITGSSDSTV 365
Query: 761 IITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT--LLSTVTA 818
+ + G ++ L HH +V ++ + + +T S+D ++ W++ + T L V
Sbjct: 366 RVWDVNTGEMLNTLIHHCEAVLHLRF--NNGMMVTCSKDRSIAVWDMASPTDITLRRVLV 423
Query: 819 GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAV 878
G + V D+ ++++ GD + + T ++ L HK + C+ + V
Sbjct: 424 GHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA--CLQYRDRLVVS 481
Query: 879 GCADQRIYLYSLHSAQLLR 897
G +D I L+ + LR
Sbjct: 482 GSSDNTIRLWDIECGACLR 500
Score = 70.5 bits (165), Expect = 4e-11
Identities = 53/205 (25%), Positives = 97/205 (47%), Gaps = 12/205 (5%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+GS+LC+ + + ++TGS D++V VWD++T + ++ H VL + N ++
Sbjct: 341 GHTGSVLCL--QYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLR--FNNGMM 396
Query: 752 ISGGDDSAVII---TSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
++ D ++ + S D L L HR +V V D ++ S D T+ WN
Sbjct: 397 VTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWNTS 454
Query: 809 NFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFC 868
+ T+ G I + + +++ DN + L G L L+ H+ V+ C
Sbjct: 455 TCEFVRTLN-GHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVR--C 511
Query: 869 VAHDSSRVAVGCADQRIYLYSLHSA 893
+ D+ R+ G D +I ++ L +A
Sbjct: 512 IRFDNKRIVSGAYDGKIKVWDLVAA 536
Score = 52.4 bits (120), Expect = 1e-05
Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 14/208 (6%)
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDGDNSVRIWSLA 1119
D ++ +S R + +W ++ TG + S+ + + + + D++VR+W +
Sbjct: 312 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVN 371
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK---LSQVLVGHS 1176
G E + H E + L ++ +VT S D S+ VW + L +VLVGH
Sbjct: 372 TG---EMLNTLIHHCEAV--LHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHR 426
Query: 1177 DIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVS 1236
V V +K +VS S D + VW+ +T + C++ + VS
Sbjct: 427 AAVN--VVDFDDK-YIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRD--RLVVS 481
Query: 1237 CAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+ D T+ +W+ + G L H L+
Sbjct: 482 GSSDNTIRLWDIECGACLRVLEGHEELV 509
Score = 39.9 bits (89), Expect = 0.066
Identities = 35/154 (22%), Positives = 65/154 (42%), Gaps = 15/154 (9%)
Query: 665 QHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLH 724
+++V A ++W+ + V T GH I C+ + +++GS D ++ +WD+
Sbjct: 437 KYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACL--QYRDRLVVSGSSDNTIRLWDIE 494
Query: 725 TLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLV--------DGALVTK-LD 775
A + H V C+ + ++SG D + + LV G L + L
Sbjct: 495 CGACLRVLEGHEELVRCIR--FDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLV 552
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
H G V ++ D ++ S D T+ W+ N
Sbjct: 553 EHSGRVFRLQF--DEFQIVSSSHDDTILIWDFLN 584
>AL133387-2|CAH70019.1| 569|Homo sapiens beta-transducin repeat
containing protein.
Length = 569
Score = 101 bits (241), Expect = 3e-20
Identities = 77/288 (26%), Positives = 131/288 (45%), Gaps = 21/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ CL+ D Q SG +++W +T + L GH G + C+ + ++++GS
Sbjct: 270 VYCLQY--DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDER--VIITGSS 325
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D TV VW + T H A+ L + S DR+ V + I L
Sbjct: 326 DSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRV 385
Query: 1089 -TGPSASIDVT-LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
G A+++V + KY V + GD ++++W+ + E R H I C L
Sbjct: 386 LVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTS---TCEFVRTLNGHKRGIAC--LQYRD 440
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+ VV+GS D ++++W ++ G +VL GH ++V C + NK ++VSG++D + VWD+
Sbjct: 441 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC--IRFDNK-RIVSGAYDGKIKVWDL 497
Query: 1207 NTXXXXXXXXXXXXKVTCVKVTG-------DGTIAVSCAEDKTLIIWE 1247
T V+ +G D VS + D T++IW+
Sbjct: 498 VAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWD 545
Score = 74.1 bits (174), Expect = 3e-12
Identities = 47/199 (23%), Positives = 94/199 (47%), Gaps = 8/199 (4%)
Query: 701 CVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAV 760
C+ + Q +++G D ++ +WD +TL K + H VLC+ + ++I+G DS V
Sbjct: 272 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQ--YDERVIITGSSDSTV 329
Query: 761 IITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT--LLSTVTA 818
+ + G ++ L HH +V ++ + + +T S+D ++ W++ + T L V
Sbjct: 330 RVWDVNTGEMLNTLIHHCEAVLHLRF--NNGMMVTCSKDRSIAVWDMASPTDITLRRVLV 387
Query: 819 GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAV 878
G + V D+ ++++ GD + + T ++ L HK + C+ + V
Sbjct: 388 GHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA--CLQYRDRLVVS 445
Query: 879 GCADQRIYLYSLHSAQLLR 897
G +D I L+ + LR
Sbjct: 446 GSSDNTIRLWDIECGACLR 464
Score = 70.5 bits (165), Expect = 4e-11
Identities = 53/205 (25%), Positives = 97/205 (47%), Gaps = 12/205 (5%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+GS+LC+ + + ++TGS D++V VWD++T + ++ H VL + N ++
Sbjct: 305 GHTGSVLCL--QYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLR--FNNGMM 360
Query: 752 ISGGDDSAVII---TSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
++ D ++ + S D L L HR +V V D ++ S D T+ WN
Sbjct: 361 VTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWNTS 418
Query: 809 NFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFC 868
+ T+ G I + + +++ DN + L G L L+ H+ V+ C
Sbjct: 419 TCEFVRTLN-GHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVR--C 475
Query: 869 VAHDSSRVAVGCADQRIYLYSLHSA 893
+ D+ R+ G D +I ++ L +A
Sbjct: 476 IRFDNKRIVSGAYDGKIKVWDLVAA 500
Score = 52.4 bits (120), Expect = 1e-05
Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 14/208 (6%)
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDGDNSVRIWSLA 1119
D ++ +S R + +W ++ TG + S+ + + + + D++VR+W +
Sbjct: 276 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVN 335
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK---LSQVLVGHS 1176
G E + H E + L ++ +VT S D S+ VW + L +VLVGH
Sbjct: 336 TG---EMLNTLIHHCEAV--LHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHR 390
Query: 1177 DIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVS 1236
V V +K +VS S D + VW+ +T + C++ + VS
Sbjct: 391 AAVN--VVDFDDK-YIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRD--RLVVS 445
Query: 1237 CAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+ D T+ +W+ + G L H L+
Sbjct: 446 GSSDNTIRLWDIECGACLRVLEGHEELV 473
Score = 39.9 bits (89), Expect = 0.066
Identities = 35/154 (22%), Positives = 65/154 (42%), Gaps = 15/154 (9%)
Query: 665 QHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLH 724
+++V A ++W+ + V T GH I C+ + +++GS D ++ +WD+
Sbjct: 401 KYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACL--QYRDRLVVSGSSDNTIRLWDIE 458
Query: 725 TLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLV--------DGALVTK-LD 775
A + H V C+ + ++SG D + + LV G L + L
Sbjct: 459 CGACLRVLEGHEELVRCIR--FDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLV 516
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
H G V ++ D ++ S D T+ W+ N
Sbjct: 517 EHSGRVFRLQF--DEFQIVSSSHDDTILIWDFLN 548
>AL133387-1|CAH70020.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 101 bits (241), Expect = 3e-20
Identities = 77/288 (26%), Positives = 131/288 (45%), Gaps = 21/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ CL+ D Q SG +++W +T + L GH G + C+ + ++++GS
Sbjct: 306 VYCLQY--DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDER--VIITGSS 361
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D TV VW + T H A+ L + S DR+ V + I L
Sbjct: 362 DSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRV 421
Query: 1089 -TGPSASIDVT-LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
G A+++V + KY V + GD ++++W+ + E R H I C L
Sbjct: 422 LVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTS---TCEFVRTLNGHKRGIAC--LQYRD 476
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+ VV+GS D ++++W ++ G +VL GH ++V C + NK ++VSG++D + VWD+
Sbjct: 477 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC--IRFDNK-RIVSGAYDGKIKVWDL 533
Query: 1207 NTXXXXXXXXXXXXKVTCVKVTG-------DGTIAVSCAEDKTLIIWE 1247
T V+ +G D VS + D T++IW+
Sbjct: 534 VAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWD 581
Score = 74.1 bits (174), Expect = 3e-12
Identities = 47/199 (23%), Positives = 94/199 (47%), Gaps = 8/199 (4%)
Query: 701 CVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAV 760
C+ + Q +++G D ++ +WD +TL K + H VLC+ + ++I+G DS V
Sbjct: 308 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQ--YDERVIITGSSDSTV 365
Query: 761 IITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT--LLSTVTA 818
+ + G ++ L HH +V ++ + + +T S+D ++ W++ + T L V
Sbjct: 366 RVWDVNTGEMLNTLIHHCEAVLHLRF--NNGMMVTCSKDRSIAVWDMASPTDITLRRVLV 423
Query: 819 GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAV 878
G + V D+ ++++ GD + + T ++ L HK + C+ + V
Sbjct: 424 GHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA--CLQYRDRLVVS 481
Query: 879 GCADQRIYLYSLHSAQLLR 897
G +D I L+ + LR
Sbjct: 482 GSSDNTIRLWDIECGACLR 500
Score = 70.5 bits (165), Expect = 4e-11
Identities = 53/205 (25%), Positives = 97/205 (47%), Gaps = 12/205 (5%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+GS+LC+ + + ++TGS D++V VWD++T + ++ H VL + N ++
Sbjct: 341 GHTGSVLCL--QYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLR--FNNGMM 396
Query: 752 ISGGDDSAVII---TSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
++ D ++ + S D L L HR +V V D ++ S D T+ WN
Sbjct: 397 VTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWNTS 454
Query: 809 NFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFC 868
+ T+ G I + + +++ DN + L G L L+ H+ V+ C
Sbjct: 455 TCEFVRTLN-GHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVR--C 511
Query: 869 VAHDSSRVAVGCADQRIYLYSLHSA 893
+ D+ R+ G D +I ++ L +A
Sbjct: 512 IRFDNKRIVSGAYDGKIKVWDLVAA 536
Score = 52.4 bits (120), Expect = 1e-05
Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 14/208 (6%)
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDGDNSVRIWSLA 1119
D ++ +S R + +W ++ TG + S+ + + + + D++VR+W +
Sbjct: 312 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVN 371
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK---LSQVLVGHS 1176
G E + H E + L ++ +VT S D S+ VW + L +VLVGH
Sbjct: 372 TG---EMLNTLIHHCEAV--LHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHR 426
Query: 1177 DIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVS 1236
V V +K +VS S D + VW+ +T + C++ + VS
Sbjct: 427 AAVN--VVDFDDK-YIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRD--RLVVS 481
Query: 1237 CAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+ D T+ +W+ + G L H L+
Sbjct: 482 GSSDNTIRLWDIECGACLRVLEGHEELV 509
Score = 39.9 bits (89), Expect = 0.066
Identities = 35/154 (22%), Positives = 65/154 (42%), Gaps = 15/154 (9%)
Query: 665 QHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLH 724
+++V A ++W+ + V T GH I C+ + +++GS D ++ +WD+
Sbjct: 437 KYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACL--QYRDRLVVSGSSDNTIRLWDIE 494
Query: 725 TLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLV--------DGALVTK-LD 775
A + H V C+ + ++SG D + + LV G L + L
Sbjct: 495 CGACLRVLEGHEELVRCIR--FDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLV 552
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
H G V ++ D ++ S D T+ W+ N
Sbjct: 553 EHSGRVFRLQF--DEFQIVSSSHDDTILIWDFLN 584
>AF129530-1|AAF04464.1| 569|Homo sapiens F-box protein Fbw1A protein.
Length = 569
Score = 101 bits (241), Expect = 3e-20
Identities = 77/288 (26%), Positives = 131/288 (45%), Gaps = 21/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ CL+ D Q SG +++W +T + L GH G + C+ + ++++GS
Sbjct: 270 VYCLQY--DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDER--VIITGSS 325
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D TV VW + T H A+ L + S DR+ V + I L
Sbjct: 326 DSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRV 385
Query: 1089 -TGPSASIDVT-LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
G A+++V + KY V + GD ++++W+ + E R H I C L
Sbjct: 386 LVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTS---TCEFVRTLNGHKRGIAC--LQYRD 440
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+ VV+GS D ++++W ++ G +VL GH ++V C + NK ++VSG++D + VWD+
Sbjct: 441 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC--IRFDNK-RIVSGAYDGKIKVWDL 497
Query: 1207 NTXXXXXXXXXXXXKVTCVKVTG-------DGTIAVSCAEDKTLIIWE 1247
T V+ +G D VS + D T++IW+
Sbjct: 498 VAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWD 545
Score = 74.1 bits (174), Expect = 3e-12
Identities = 47/199 (23%), Positives = 94/199 (47%), Gaps = 8/199 (4%)
Query: 701 CVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAV 760
C+ + Q +++G D ++ +WD +TL K + H VLC+ + ++I+G DS V
Sbjct: 272 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQ--YDERVIITGSSDSTV 329
Query: 761 IITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT--LLSTVTA 818
+ + G ++ L HH +V ++ + + +T S+D ++ W++ + T L V
Sbjct: 330 RVWDVNTGEMLNTLIHHCEAVLHLRF--NNGMMVTCSKDRSIAVWDMASPTDITLRRVLV 387
Query: 819 GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAV 878
G + V D+ ++++ GD + + T ++ L HK + C+ + V
Sbjct: 388 GHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA--CLQYRDRLVVS 445
Query: 879 GCADQRIYLYSLHSAQLLR 897
G +D I L+ + LR
Sbjct: 446 GSSDNTIRLWDIECGACLR 464
Score = 70.5 bits (165), Expect = 4e-11
Identities = 53/205 (25%), Positives = 97/205 (47%), Gaps = 12/205 (5%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+GS+LC+ + + ++TGS D++V VWD++T + ++ H VL + N ++
Sbjct: 305 GHTGSVLCL--QYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLR--FNNGMM 360
Query: 752 ISGGDDSAVII---TSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
++ D ++ + S D L L HR +V V D ++ S D T+ WN
Sbjct: 361 VTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWNTS 418
Query: 809 NFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFC 868
+ T+ G I + + +++ DN + L G L L+ H+ V+ C
Sbjct: 419 TCEFVRTLN-GHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVR--C 475
Query: 869 VAHDSSRVAVGCADQRIYLYSLHSA 893
+ D+ R+ G D +I ++ L +A
Sbjct: 476 IRFDNKRIVSGAYDGKIKVWDLVAA 500
Score = 52.4 bits (120), Expect = 1e-05
Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 14/208 (6%)
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDGDNSVRIWSLA 1119
D ++ +S R + +W ++ TG + S+ + + + + D++VR+W +
Sbjct: 276 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVN 335
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK---LSQVLVGHS 1176
G E + H E + L ++ +VT S D S+ VW + L +VLVGH
Sbjct: 336 TG---EMLNTLIHHCEAV--LHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHR 390
Query: 1177 DIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVS 1236
V V +K +VS S D + VW+ +T + C++ + VS
Sbjct: 391 AAVN--VVDFDDK-YIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRD--RLVVS 445
Query: 1237 CAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+ D T+ +W+ + G L H L+
Sbjct: 446 GSSDNTIRLWDIECGACLRVLEGHEELV 473
Score = 39.9 bits (89), Expect = 0.066
Identities = 35/154 (22%), Positives = 65/154 (42%), Gaps = 15/154 (9%)
Query: 665 QHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLH 724
+++V A ++W+ + V T GH I C+ + +++GS D ++ +WD+
Sbjct: 401 KYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACL--QYRDRLVVSGSSDNTIRLWDIE 458
Query: 725 TLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLV--------DGALVTK-LD 775
A + H V C+ + ++SG D + + LV G L + L
Sbjct: 459 CGACLRVLEGHEELVRCIR--FDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLV 516
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
H G V ++ D ++ S D T+ W+ N
Sbjct: 517 EHSGRVFRLQF--DEFQIVSSSHDDTILIWDFLN 548
>AF101784-1|AAD08702.1| 605|Homo sapiens b-TRCP variant E3RS-IkappaB
protein.
Length = 605
Score = 101 bits (241), Expect = 3e-20
Identities = 77/288 (26%), Positives = 131/288 (45%), Gaps = 21/288 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ CL+ D Q SG +++W +T + L GH G + C+ + ++++GS
Sbjct: 306 VYCLQY--DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDER--VIITGSS 361
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D TV VW + T H A+ L + S DR+ V + I L
Sbjct: 362 DSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRV 421
Query: 1089 -TGPSASIDVT-LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
G A+++V + KY V + GD ++++W+ + E R H I C L
Sbjct: 422 LVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTS---TCEFVRTLNGHKRGIAC--LQYRD 476
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+ VV+GS D ++++W ++ G +VL GH ++V C + NK ++VSG++D + VWD+
Sbjct: 477 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC--IRFDNK-RIVSGAYDGKIKVWDL 533
Query: 1207 NTXXXXXXXXXXXXKVTCVKVTG-------DGTIAVSCAEDKTLIIWE 1247
T V+ +G D VS + D T++IW+
Sbjct: 534 VAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWD 581
Score = 74.1 bits (174), Expect = 3e-12
Identities = 47/199 (23%), Positives = 94/199 (47%), Gaps = 8/199 (4%)
Query: 701 CVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAV 760
C+ + Q +++G D ++ +WD +TL K + H VLC+ + ++I+G DS V
Sbjct: 308 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQ--YDERVIITGSSDSTV 365
Query: 761 IITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT--LLSTVTA 818
+ + G ++ L HH +V ++ + + +T S+D ++ W++ + T L V
Sbjct: 366 RVWDVNTGEMLNTLIHHCEAVLHLRF--NNGMMVTCSKDRSIAVWDMASPTDITLRRVLV 423
Query: 819 GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAV 878
G + V D+ ++++ GD + + T ++ L HK + C+ + V
Sbjct: 424 GHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA--CLQYRDRLVVS 481
Query: 879 GCADQRIYLYSLHSAQLLR 897
G +D I L+ + LR
Sbjct: 482 GSSDNTIRLWDIECGACLR 500
Score = 70.5 bits (165), Expect = 4e-11
Identities = 53/205 (25%), Positives = 97/205 (47%), Gaps = 12/205 (5%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+GS+LC+ + + ++TGS D++V VWD++T + ++ H VL + N ++
Sbjct: 341 GHTGSVLCL--QYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLR--FNNGMM 396
Query: 752 ISGGDDSAVII---TSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
++ D ++ + S D L L HR +V V D ++ S D T+ WN
Sbjct: 397 VTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWNTS 454
Query: 809 NFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFC 868
+ T+ G I + + +++ DN + L G L L+ H+ V+ C
Sbjct: 455 TCEFVRTLN-GHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVR--C 511
Query: 869 VAHDSSRVAVGCADQRIYLYSLHSA 893
+ D+ R+ G D +I ++ L +A
Sbjct: 512 IRFDNKRIVSGAYDGKIKVWDLVAA 536
Score = 52.4 bits (120), Expect = 1e-05
Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 14/208 (6%)
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDGDNSVRIWSLA 1119
D ++ +S R + +W ++ TG + S+ + + + + D++VR+W +
Sbjct: 312 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVN 371
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK---LSQVLVGHS 1176
G E + H E + L ++ +VT S D S+ VW + L +VLVGH
Sbjct: 372 TG---EMLNTLIHHCEAV--LHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHR 426
Query: 1177 DIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVS 1236
V V +K +VS S D + VW+ +T + C++ + VS
Sbjct: 427 AAVN--VVDFDDK-YIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRD--RLVVS 481
Query: 1237 CAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+ D T+ +W+ + G L H L+
Sbjct: 482 GSSDNTIRLWDIECGACLRVLEGHEELV 509
Score = 39.9 bits (89), Expect = 0.066
Identities = 35/154 (22%), Positives = 65/154 (42%), Gaps = 15/154 (9%)
Query: 665 QHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLH 724
+++V A ++W+ + V T GH I C+ + +++GS D ++ +WD+
Sbjct: 437 KYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACL--QYRDRLVVSGSSDNTIRLWDIE 494
Query: 725 TLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLV--------DGALVTK-LD 775
A + H V C+ + ++SG D + + LV G L + L
Sbjct: 495 CGACLRVLEGHEELVRCIR--FDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLV 552
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
H G V ++ D ++ S D T+ W+ N
Sbjct: 553 EHSGRVFRLQF--DEFQIVSSSHDDTILIWDFLN 584
>BX649632-1|CAI18774.1| 334|Homo sapiens WD repeat domain 5 protein.
Length = 334
Score = 97.5 bits (232), Expect = 3e-19
Identities = 77/330 (23%), Positives = 141/330 (42%), Gaps = 20/330 (6%)
Query: 933 EDNLTNFRPTKQMKRRQTKSTT---NITLLQAEQSDLIPISCLEVSRDGQLGASGCARGL 989
E +PT Q+K T N L +S ++ S +G+ AS A L
Sbjct: 9 ETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKL 68
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
+++W + + T++GH I+ V +S ++ L++S S+D+T+ +W ++ T KGH
Sbjct: 69 IKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGH 128
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA---TGPSASIDVTLNMKYAVL 1106
S+ + +S +V +W V +G L + + P +++ + V
Sbjct: 129 SNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVS 188
Query: 1107 SDGDNSVRIWSLAGGD----NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWK 1162
S D RIW A G +D+ VS + + + ++++ ++D +LK+W
Sbjct: 189 SSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVK------FSPNGKYILAATLDNTLKLWD 242
Query: 1163 LDGGKLSQVLVGHSDIVTCVAV--SITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
GK + GH + C+ S+T +VSGS D + +W++ T
Sbjct: 243 YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTD 302
Query: 1221 KVTCVKVTGDGTIAVSCA--EDKTLIIWET 1248
V I S A DKT+ +W++
Sbjct: 303 VVISTACHPTENIIASAALENDKTIKLWKS 332
Score = 77.8 bits (183), Expect = 3e-13
Identities = 46/162 (28%), Positives = 78/162 (48%), Gaps = 4/162 (2%)
Query: 1093 ASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTG 1152
+S+ + N ++ S D ++IW G + + + H I+ A ++DS +V+
Sbjct: 49 SSVKFSPNGEWLASSSADKLIKIW---GAYDGKFEKTISGHKLGISDVAWSSDSNLLVSA 105
Query: 1153 SMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXX 1212
S D +LK+W + GK + L GHS+ V C + +VSGS+D ++ +WD+ T
Sbjct: 106 SDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFN-PQSNLIVSGSFDESVRIWDVKTGKCL 164
Query: 1213 XXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLAL 1254
V+ V DG++ VS + D IW+T G L
Sbjct: 165 KTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCL 206
Score = 75.4 bits (177), Expect = 1e-12
Identities = 51/245 (20%), Positives = 105/245 (42%), Gaps = 5/245 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
++ +P+G+ L + + ++W T GH I + + +S L++ S+D +
Sbjct: 51 VKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKT 110
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ +WD+ + + H V C +L++SG D +V I + G + L H
Sbjct: 111 LKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAH 170
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV--TAGVPIHIFDVTDDNVFLL 835
V++V +DG++ ++ S DG W+ + L T+ P+ + + ++L
Sbjct: 171 SDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYIL 230
Query: 836 TLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCV---AHDSSRVAVGCADQRIYLYSLHS 892
DN L L + G L HK + C + G D +Y+++L +
Sbjct: 231 AATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQT 290
Query: 893 AQLLR 897
++++
Sbjct: 291 KEIVQ 295
Score = 74.5 bits (175), Expect = 2e-12
Identities = 52/220 (23%), Positives = 100/220 (45%), Gaps = 8/220 (3%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DV--TLNM 1101
T GH+ A+ ++ +G SS + + +W G + +G I DV + +
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 99
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
V + D +++IW ++ G + + H+ + C S +V+GS D S+++W
Sbjct: 100 NLLVSASDDKTLKIWDVSSGKCLKTLK---GHSNYVFCCNFNPQSNLIVSGSFDESVRIW 156
Query: 1162 KLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK 1221
+ GK + L HSD V+ V + + + +VS S+D +WD +
Sbjct: 157 DVKTGKCLKTLPAHSDPVSAVHFN-RDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNP 215
Query: 1222 -VTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
V+ VK + +G ++ D TL +W+ +G L +++ H
Sbjct: 216 PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGH 255
Score = 56.0 bits (129), Expect = 9e-07
Identities = 35/153 (22%), Positives = 66/153 (43%), Gaps = 2/153 (1%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H + ++ + + + + + S D +K+W GK + + GH ++ VA S ++ +
Sbjct: 44 HTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWS-SDSNLL 102
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
VS S D L +WD+++ V C + VS + D+++ IW+ K G
Sbjct: 103 VSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGK 162
Query: 1253 ALTSFSLHV-PLLGFQITSDCARVVVHLLDRGC 1284
L + H P+ D + +V D C
Sbjct: 163 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLC 195
Score = 49.2 bits (112), Expect = 1e-04
Identities = 30/130 (23%), Positives = 57/130 (43%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T GH+ ++ + + ++L + S D + +W + + I H + VA +
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 99
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
+L++S DD + I + G + L H V N+ ++GS D +V W+V+
Sbjct: 100 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 159
Query: 809 NFTLLSTVTA 818
L T+ A
Sbjct: 160 TGKCLKTLPA 169
Score = 45.6 bits (103), Expect = 0.001
Identities = 40/174 (22%), Positives = 65/174 (37%), Gaps = 3/174 (1%)
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
A+K + H V V N + S D + I DG + H+ ++ V
Sbjct: 36 ALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAW 95
Query: 787 IQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG--DNELH 844
D N+ ++ S D T+ W+V + L T+ G ++F + L + G D +
Sbjct: 96 SSDSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVR 154
Query: 845 LRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ TG L L H V D S + D ++ S Q L+T
Sbjct: 155 IWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKT 208
Score = 45.6 bits (103), Expect = 0.001
Identities = 22/99 (22%), Positives = 47/99 (47%), Gaps = 3/99 (3%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRE---SQYLLTGSE 714
++ +P+G++++ A +LW + T+ GH C+ +++++GSE
Sbjct: 220 VKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSE 279
Query: 715 DTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVIS 753
D V +W+L T + K+ H V+ A +++ S
Sbjct: 280 DNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIAS 318
>BC001635-1|AAH01635.1| 334|Homo sapiens WD repeat domain 5 protein.
Length = 334
Score = 97.5 bits (232), Expect = 3e-19
Identities = 77/330 (23%), Positives = 141/330 (42%), Gaps = 20/330 (6%)
Query: 933 EDNLTNFRPTKQMKRRQTKSTT---NITLLQAEQSDLIPISCLEVSRDGQLGASGCARGL 989
E +PT Q+K T N L +S ++ S +G+ AS A L
Sbjct: 9 ETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKL 68
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
+++W + + T++GH I+ V +S ++ L++S S+D+T+ +W ++ T KGH
Sbjct: 69 IKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGH 128
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA---TGPSASIDVTLNMKYAVL 1106
S+ + +S +V +W V +G L + + P +++ + V
Sbjct: 129 SNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVS 188
Query: 1107 SDGDNSVRIWSLAGGD----NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWK 1162
S D RIW A G +D+ VS + + + ++++ ++D +LK+W
Sbjct: 189 SSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVK------FSPNGKYILAATLDNTLKLWD 242
Query: 1163 LDGGKLSQVLVGHSDIVTCVAV--SITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
GK + GH + C+ S+T +VSGS D + +W++ T
Sbjct: 243 YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTD 302
Query: 1221 KVTCVKVTGDGTIAVSCA--EDKTLIIWET 1248
V I S A DKT+ +W++
Sbjct: 303 VVISTACHPTENIIASAALENDKTIKLWKS 332
Score = 77.8 bits (183), Expect = 3e-13
Identities = 46/162 (28%), Positives = 78/162 (48%), Gaps = 4/162 (2%)
Query: 1093 ASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTG 1152
+S+ + N ++ S D ++IW G + + + H I+ A ++DS +V+
Sbjct: 49 SSVKFSPNGEWLASSSADKLIKIW---GAYDGKFEKTISGHKLGISDVAWSSDSNLLVSA 105
Query: 1153 SMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXX 1212
S D +LK+W + GK + L GHS+ V C + +VSGS+D ++ +WD+ T
Sbjct: 106 SDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFN-PQSNLIVSGSFDESVRIWDVKTGKCL 164
Query: 1213 XXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLAL 1254
V+ V DG++ VS + D IW+T G L
Sbjct: 165 KTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCL 206
Score = 75.4 bits (177), Expect = 1e-12
Identities = 51/245 (20%), Positives = 105/245 (42%), Gaps = 5/245 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
++ +P+G+ L + + ++W T GH I + + +S L++ S+D +
Sbjct: 51 VKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKT 110
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ +WD+ + + H V C +L++SG D +V I + G + L H
Sbjct: 111 LKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAH 170
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV--TAGVPIHIFDVTDDNVFLL 835
V++V +DG++ ++ S DG W+ + L T+ P+ + + ++L
Sbjct: 171 SDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYIL 230
Query: 836 TLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCV---AHDSSRVAVGCADQRIYLYSLHS 892
DN L L + G L HK + C + G D +Y+++L +
Sbjct: 231 AATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQT 290
Query: 893 AQLLR 897
++++
Sbjct: 291 KEIVQ 295
Score = 74.5 bits (175), Expect = 2e-12
Identities = 52/220 (23%), Positives = 100/220 (45%), Gaps = 8/220 (3%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DV--TLNM 1101
T GH+ A+ ++ +G SS + + +W G + +G I DV + +
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 99
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
V + D +++IW ++ G + + H+ + C S +V+GS D S+++W
Sbjct: 100 NLLVSASDDKTLKIWDVSSGKCLKTLK---GHSNYVFCCNFNPQSNLIVSGSFDESVRIW 156
Query: 1162 KLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK 1221
+ GK + L HSD V+ V + + + +VS S+D +WD +
Sbjct: 157 DVKTGKCLKTLPAHSDPVSAVHFN-RDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNP 215
Query: 1222 -VTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
V+ VK + +G ++ D TL +W+ +G L +++ H
Sbjct: 216 PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGH 255
Score = 56.0 bits (129), Expect = 9e-07
Identities = 35/153 (22%), Positives = 66/153 (43%), Gaps = 2/153 (1%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H + ++ + + + + + S D +K+W GK + + GH ++ VA S ++ +
Sbjct: 44 HTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWS-SDSNLL 102
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
VS S D L +WD+++ V C + VS + D+++ IW+ K G
Sbjct: 103 VSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGK 162
Query: 1253 ALTSFSLHV-PLLGFQITSDCARVVVHLLDRGC 1284
L + H P+ D + +V D C
Sbjct: 163 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLC 195
Score = 49.2 bits (112), Expect = 1e-04
Identities = 30/130 (23%), Positives = 57/130 (43%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T GH+ ++ + + ++L + S D + +W + + I H + VA +
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 99
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
+L++S DD + I + G + L H V N+ ++GS D +V W+V+
Sbjct: 100 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 159
Query: 809 NFTLLSTVTA 818
L T+ A
Sbjct: 160 TGKCLKTLPA 169
Score = 45.6 bits (103), Expect = 0.001
Identities = 40/174 (22%), Positives = 65/174 (37%), Gaps = 3/174 (1%)
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
A+K + H V V N + S D + I DG + H+ ++ V
Sbjct: 36 ALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAW 95
Query: 787 IQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG--DNELH 844
D N+ ++ S D T+ W+V + L T+ G ++F + L + G D +
Sbjct: 96 SSDSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVR 154
Query: 845 LRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ TG L L H V D S + D ++ S Q L+T
Sbjct: 155 IWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKT 208
Score = 45.6 bits (103), Expect = 0.001
Identities = 22/99 (22%), Positives = 47/99 (47%), Gaps = 3/99 (3%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRE---SQYLLTGSE 714
++ +P+G++++ A +LW + T+ GH C+ +++++GSE
Sbjct: 220 VKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSE 279
Query: 715 DTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVIS 753
D V +W+L T + K+ H V+ A +++ S
Sbjct: 280 DNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIAS 318
>AK000552-1|BAA91248.1| 334|Homo sapiens protein ( Homo sapiens cDNA
FLJ20545 fis, clone KAT11476. ).
Length = 334
Score = 97.5 bits (232), Expect = 3e-19
Identities = 77/330 (23%), Positives = 141/330 (42%), Gaps = 20/330 (6%)
Query: 933 EDNLTNFRPTKQMKRRQTKSTT---NITLLQAEQSDLIPISCLEVSRDGQLGASGCARGL 989
E +PT Q+K T N L +S ++ S +G+ AS A L
Sbjct: 9 ETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKL 68
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
+++W + + T++GH I+ V +S ++ L++S S+D+T+ +W ++ T KGH
Sbjct: 69 IKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGH 128
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA---TGPSASIDVTLNMKYAVL 1106
S+ + +S +V +W V +G L + + P +++ + V
Sbjct: 129 SNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVS 188
Query: 1107 SDGDNSVRIWSLAGGD----NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWK 1162
S D RIW A G +D+ VS + + + ++++ ++D +LK+W
Sbjct: 189 SSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVK------FSPNGKYILAATLDNTLKLWD 242
Query: 1163 LDGGKLSQVLVGHSDIVTCVAV--SITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
GK + GH + C+ S+T +VSGS D + +W++ T
Sbjct: 243 YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTD 302
Query: 1221 KVTCVKVTGDGTIAVSCA--EDKTLIIWET 1248
V I S A DKT+ +W++
Sbjct: 303 VVISTACHPTENIIASAALENDKTIKLWKS 332
Score = 77.8 bits (183), Expect = 3e-13
Identities = 46/162 (28%), Positives = 78/162 (48%), Gaps = 4/162 (2%)
Query: 1093 ASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTG 1152
+S+ + N ++ S D ++IW G + + + H I+ A ++DS +V+
Sbjct: 49 SSVKFSPNGEWLASSSADKLIKIW---GAYDGKFEKTISGHKLGISDVAWSSDSNLLVSA 105
Query: 1153 SMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXX 1212
S D +LK+W + GK + L GHS+ V C + +VSGS+D ++ +WD+ T
Sbjct: 106 SDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFN-PQSNLIVSGSFDESVRIWDVKTGKCL 164
Query: 1213 XXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLAL 1254
V+ V DG++ VS + D IW+T G L
Sbjct: 165 KTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCL 206
Score = 75.4 bits (177), Expect = 1e-12
Identities = 51/245 (20%), Positives = 105/245 (42%), Gaps = 5/245 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
++ +P+G+ L + + ++W T GH I + + +S L++ S+D +
Sbjct: 51 VKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKT 110
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ +WD+ + + H V C +L++SG D +V I + G + L H
Sbjct: 111 LKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAH 170
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV--TAGVPIHIFDVTDDNVFLL 835
V++V +DG++ ++ S DG W+ + L T+ P+ + + ++L
Sbjct: 171 SDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYIL 230
Query: 836 TLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCV---AHDSSRVAVGCADQRIYLYSLHS 892
DN L L + G L HK + C + G D +Y+++L +
Sbjct: 231 AATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQT 290
Query: 893 AQLLR 897
++++
Sbjct: 291 KEIVQ 295
Score = 74.5 bits (175), Expect = 2e-12
Identities = 52/220 (23%), Positives = 100/220 (45%), Gaps = 8/220 (3%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DV--TLNM 1101
T GH+ A+ ++ +G SS + + +W G + +G I DV + +
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 99
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
V + D +++IW ++ G + + H+ + C S +V+GS D S+++W
Sbjct: 100 NLLVSASDDKTLKIWDVSSGKCLKTLK---GHSNYVFCCNFNPQSNLIVSGSFDESVRIW 156
Query: 1162 KLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK 1221
+ GK + L HSD V+ V + + + +VS S+D +WD +
Sbjct: 157 DVKTGKCLKTLPAHSDPVSAVHFN-RDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNP 215
Query: 1222 -VTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
V+ VK + +G ++ D TL +W+ +G L +++ H
Sbjct: 216 PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGH 255
Score = 56.0 bits (129), Expect = 9e-07
Identities = 35/153 (22%), Positives = 66/153 (43%), Gaps = 2/153 (1%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H + ++ + + + + + S D +K+W GK + + GH ++ VA S ++ +
Sbjct: 44 HTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWS-SDSNLL 102
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
VS S D L +WD+++ V C + VS + D+++ IW+ K G
Sbjct: 103 VSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGK 162
Query: 1253 ALTSFSLHV-PLLGFQITSDCARVVVHLLDRGC 1284
L + H P+ D + +V D C
Sbjct: 163 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLC 195
Score = 49.2 bits (112), Expect = 1e-04
Identities = 30/130 (23%), Positives = 57/130 (43%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T GH+ ++ + + ++L + S D + +W + + I H + VA +
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 99
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
+L++S DD + I + G + L H V N+ ++GS D +V W+V+
Sbjct: 100 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 159
Query: 809 NFTLLSTVTA 818
L T+ A
Sbjct: 160 TGKCLKTLPA 169
Score = 45.6 bits (103), Expect = 0.001
Identities = 40/174 (22%), Positives = 65/174 (37%), Gaps = 3/174 (1%)
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
A+K + H V V N + S D + I DG + H+ ++ V
Sbjct: 36 ALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAW 95
Query: 787 IQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG--DNELH 844
D N+ ++ S D T+ W+V + L T+ G ++F + L + G D +
Sbjct: 96 SSDSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVR 154
Query: 845 LRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ TG L L H V D S + D ++ S Q L+T
Sbjct: 155 IWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKT 208
Score = 45.6 bits (103), Expect = 0.001
Identities = 22/99 (22%), Positives = 47/99 (47%), Gaps = 3/99 (3%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRE---SQYLLTGSE 714
++ +P+G++++ A +LW + T+ GH C+ +++++GSE
Sbjct: 220 VKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSE 279
Query: 715 DTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVIS 753
D V +W+L T + K+ H V+ A +++ S
Sbjct: 280 DNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIAS 318
>AJ011376-1|CAB66159.1| 362|Homo sapiens hypothetical protein
protein.
Length = 362
Score = 97.5 bits (232), Expect = 3e-19
Identities = 77/330 (23%), Positives = 141/330 (42%), Gaps = 20/330 (6%)
Query: 933 EDNLTNFRPTKQMKRRQTKSTT---NITLLQAEQSDLIPISCLEVSRDGQLGASGCARGL 989
E +PT Q+K T N L +S ++ S +G+ AS A L
Sbjct: 37 ETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKL 96
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
+++W + + T++GH I+ V +S ++ L++S S+D+T+ +W ++ T KGH
Sbjct: 97 IKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGH 156
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA---TGPSASIDVTLNMKYAVL 1106
S+ + +S +V +W V +G L + + P +++ + V
Sbjct: 157 SNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVS 216
Query: 1107 SDGDNSVRIWSLAGGD----NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWK 1162
S D RIW A G +D+ VS + + + ++++ ++D +LK+W
Sbjct: 217 SSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVK------FSPNGKYILAATLDNTLKLWD 270
Query: 1163 LDGGKLSQVLVGHSDIVTCVAV--SITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
GK + GH + C+ S+T +VSGS D + +W++ T
Sbjct: 271 YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTD 330
Query: 1221 KVTCVKVTGDGTIAVSCA--EDKTLIIWET 1248
V I S A DKT+ +W++
Sbjct: 331 VVISTACHPTENIIASAALENDKTIKLWKS 360
Score = 77.8 bits (183), Expect = 3e-13
Identities = 46/162 (28%), Positives = 78/162 (48%), Gaps = 4/162 (2%)
Query: 1093 ASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTG 1152
+S+ + N ++ S D ++IW G + + + H I+ A ++DS +V+
Sbjct: 77 SSVKFSPNGEWLASSSADKLIKIW---GAYDGKFEKTISGHKLGISDVAWSSDSNLLVSA 133
Query: 1153 SMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXX 1212
S D +LK+W + GK + L GHS+ V C + +VSGS+D ++ +WD+ T
Sbjct: 134 SDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFN-PQSNLIVSGSFDESVRIWDVKTGKCL 192
Query: 1213 XXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLAL 1254
V+ V DG++ VS + D IW+T G L
Sbjct: 193 KTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCL 234
Score = 75.4 bits (177), Expect = 1e-12
Identities = 51/245 (20%), Positives = 105/245 (42%), Gaps = 5/245 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
++ +P+G+ L + + ++W T GH I + + +S L++ S+D +
Sbjct: 79 VKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKT 138
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ +WD+ + + H V C +L++SG D +V I + G + L H
Sbjct: 139 LKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAH 198
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV--TAGVPIHIFDVTDDNVFLL 835
V++V +DG++ ++ S DG W+ + L T+ P+ + + ++L
Sbjct: 199 SDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYIL 258
Query: 836 TLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCV---AHDSSRVAVGCADQRIYLYSLHS 892
DN L L + G L HK + C + G D +Y+++L +
Sbjct: 259 AATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQT 318
Query: 893 AQLLR 897
++++
Sbjct: 319 KEIVQ 323
Score = 74.5 bits (175), Expect = 2e-12
Identities = 52/220 (23%), Positives = 100/220 (45%), Gaps = 8/220 (3%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DV--TLNM 1101
T GH+ A+ ++ +G SS + + +W G + +G I DV + +
Sbjct: 68 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 127
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
V + D +++IW ++ G + + H+ + C S +V+GS D S+++W
Sbjct: 128 NLLVSASDDKTLKIWDVSSGKCLKTLK---GHSNYVFCCNFNPQSNLIVSGSFDESVRIW 184
Query: 1162 KLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK 1221
+ GK + L HSD V+ V + + + +VS S+D +WD +
Sbjct: 185 DVKTGKCLKTLPAHSDPVSAVHFN-RDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNP 243
Query: 1222 -VTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
V+ VK + +G ++ D TL +W+ +G L +++ H
Sbjct: 244 PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGH 283
Score = 56.0 bits (129), Expect = 9e-07
Identities = 35/153 (22%), Positives = 66/153 (43%), Gaps = 2/153 (1%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H + ++ + + + + + S D +K+W GK + + GH ++ VA S ++ +
Sbjct: 72 HTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWS-SDSNLL 130
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
VS S D L +WD+++ V C + VS + D+++ IW+ K G
Sbjct: 131 VSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGK 190
Query: 1253 ALTSFSLHV-PLLGFQITSDCARVVVHLLDRGC 1284
L + H P+ D + +V D C
Sbjct: 191 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLC 223
Score = 49.2 bits (112), Expect = 1e-04
Identities = 30/130 (23%), Positives = 57/130 (43%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T GH+ ++ + + ++L + S D + +W + + I H + VA +
Sbjct: 68 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 127
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
+L++S DD + I + G + L H V N+ ++GS D +V W+V+
Sbjct: 128 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 187
Query: 809 NFTLLSTVTA 818
L T+ A
Sbjct: 188 TGKCLKTLPA 197
Score = 45.6 bits (103), Expect = 0.001
Identities = 40/174 (22%), Positives = 65/174 (37%), Gaps = 3/174 (1%)
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
A+K + H V V N + S D + I DG + H+ ++ V
Sbjct: 64 ALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAW 123
Query: 787 IQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG--DNELH 844
D N+ ++ S D T+ W+V + L T+ G ++F + L + G D +
Sbjct: 124 SSDSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVR 182
Query: 845 LRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ TG L L H V D S + D ++ S Q L+T
Sbjct: 183 IWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKT 236
Score = 45.6 bits (103), Expect = 0.001
Identities = 22/99 (22%), Positives = 47/99 (47%), Gaps = 3/99 (3%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRE---SQYLLTGSE 714
++ +P+G++++ A +LW + T+ GH C+ +++++GSE
Sbjct: 248 VKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSE 307
Query: 715 DTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVIS 753
D V +W+L T + K+ H V+ A +++ S
Sbjct: 308 DNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIAS 346
>BC106004-1|AAI06005.1| 514|Homo sapiens pleiotropic regulator 1
(PRL1 homolog, Arabidopsis) protein.
Length = 514
Score = 94.3 bits (224), Expect = 3e-18
Identities = 61/257 (23%), Positives = 112/257 (43%), Gaps = 11/257 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
+L ++GH+G + C+ P N ++GS DRT+ +W LA L+ GH S ++ +++
Sbjct: 195 KLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 254
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSGIVL---HSATGPSASIDVTLNMKYAVLSDGDNSVRI 1115
+ S + V W ++ V+ H +D+ + V D++ RI
Sbjct: 255 STRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARI 314
Query: 1116 WSLAGGDNSEDNRRSVS-HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVG 1174
W + ++ + ++S H + A ++TGS D ++++W L GK L
Sbjct: 315 WDV----RTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTN 370
Query: 1175 HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIA 1234
H V V + + T SGS D N+ W + + V DG +
Sbjct: 371 HKKSVRAVVLHPRHYT-FASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDG-VL 427
Query: 1235 VSCAEDKTLIIWETKRG 1251
VS A++ T+ +W+ + G
Sbjct: 428 VSGADNGTMHLWDWRTG 444
Score = 86.2 bits (204), Expect = 8e-16
Identities = 59/244 (24%), Positives = 110/244 (45%), Gaps = 11/244 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ C+ V Q +G A +++W L++ +L+ +L GHI + V S + + S E
Sbjct: 207 VRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGE 266
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D+ V W L N Y GH SA+ L + ++ R +W V + +H+
Sbjct: 267 DKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTL 326
Query: 1089 TGPSASIDVTLNMKYA----VLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTA 1144
+G + ++ T+ + A + D ++R+W L G + +H + + L
Sbjct: 327 SGHTNAV-ATVRCQAAEPQIITGSHDTTIRLWDLVAG---KTRVTLTNHKKSVRAVVLHP 382
Query: 1145 DSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
+GS D ++K WK G Q L GH+ I+ +++ + +VSG+ + + +W
Sbjct: 383 RHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIIN--TLTVNSDGVLVSGADNGTMHLW 439
Query: 1205 DINT 1208
D T
Sbjct: 440 DWRT 443
Score = 62.1 bits (144), Expect = 1e-08
Identities = 46/197 (23%), Positives = 80/197 (40%), Gaps = 3/197 (1%)
Query: 670 APSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK 729
AP+ PQ WH GH G + C+ V +Q+ +TGS D ++ +WDL + +K
Sbjct: 182 APTMPKPQ-WH-PPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLK 239
Query: 730 TKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQD 789
+ HI+ V V + S G+D V L ++ H +V + +
Sbjct: 240 LSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPT 299
Query: 790 GNIFITGSQDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTF 848
++ +T S+D T W+V + T++ + ++T D + L
Sbjct: 300 IDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDL 359
Query: 849 ITGTYLHPLKRHKAKVK 865
+ G L HK V+
Sbjct: 360 VAGKTRVTLTNHKKSVR 376
Score = 58.0 bits (134), Expect = 2e-07
Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 1/128 (0%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H + C A+ +Q VTGS D ++K+W L GKL L GH V V VS T +
Sbjct: 203 HLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVS-TRSPYL 261
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
S D + WD+ V + + + V+C+ D T IW+ +
Sbjct: 262 FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKA 321
Query: 1253 ALTSFSLH 1260
++ + S H
Sbjct: 322 SVHTLSGH 329
Score = 53.2 bits (122), Expect = 7e-06
Identities = 48/222 (21%), Positives = 83/222 (37%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R + + P Q V + ++W + S + GH ++ + V+ S YL + ED
Sbjct: 208 RCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGED 267
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
V WDL V H++ V + ++++ DS I + A V L
Sbjct: 268 KQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLS 327
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLL 835
H +V +V+ ITGS D T+ W++ T+T V +
Sbjct: 328 GHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTF 387
Query: 836 TLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVA 877
+ + F G+++ L H A + V D V+
Sbjct: 388 ASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVS 429
Score = 42.3 bits (95), Expect = 0.012
Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
Query: 1167 KLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVK 1226
KL +V+ GH V C+AV N+ V+GS D + +WD+ + V V
Sbjct: 195 KLYRVISGHLGWVRCIAVEPGNQW-FVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVI 253
Query: 1227 VTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHV 1261
V+ SC EDK + W+ + + + H+
Sbjct: 254 VSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHL 288
>BC020786-1|AAH20786.1| 505|Homo sapiens PLRG1 protein protein.
Length = 505
Score = 94.3 bits (224), Expect = 3e-18
Identities = 61/257 (23%), Positives = 112/257 (43%), Gaps = 11/257 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
+L ++GH+G + C+ P N ++GS DRT+ +W LA L+ GH S ++ +++
Sbjct: 186 KLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 245
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSGIVL---HSATGPSASIDVTLNMKYAVLSDGDNSVRI 1115
+ S + V W ++ V+ H +D+ + V D++ RI
Sbjct: 246 STRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARI 305
Query: 1116 WSLAGGDNSEDNRRSVS-HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVG 1174
W + ++ + ++S H + A ++TGS D ++++W L GK L
Sbjct: 306 WDV----RTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTN 361
Query: 1175 HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIA 1234
H V V + + T SGS D N+ W + + V DG +
Sbjct: 362 HKKSVRAVVLHPRHYT-FASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDG-VL 418
Query: 1235 VSCAEDKTLIIWETKRG 1251
VS A++ T+ +W+ + G
Sbjct: 419 VSGADNGTMHLWDWRTG 435
Score = 86.2 bits (204), Expect = 8e-16
Identities = 59/244 (24%), Positives = 110/244 (45%), Gaps = 11/244 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ C+ V Q +G A +++W L++ +L+ +L GHI + V S + + S E
Sbjct: 198 VRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGE 257
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D+ V W L N Y GH SA+ L + ++ R +W V + +H+
Sbjct: 258 DKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTL 317
Query: 1089 TGPSASIDVTLNMKYA----VLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTA 1144
+G + ++ T+ + A + D ++R+W L G + +H + + L
Sbjct: 318 SGHTNAV-ATVRCQAAEPQIITGSHDTTIRLWDLVAG---KTRVTLTNHKKSVRAVVLHP 373
Query: 1145 DSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
+GS D ++K WK G Q L GH+ I+ +++ + +VSG+ + + +W
Sbjct: 374 RHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIIN--TLTVNSDGVLVSGADNGTMHLW 430
Query: 1205 DINT 1208
D T
Sbjct: 431 DWRT 434
Score = 62.1 bits (144), Expect = 1e-08
Identities = 46/197 (23%), Positives = 80/197 (40%), Gaps = 3/197 (1%)
Query: 670 APSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK 729
AP+ PQ WH GH G + C+ V +Q+ +TGS D ++ +WDL + +K
Sbjct: 173 APTMPKPQ-WH-PPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLK 230
Query: 730 TKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQD 789
+ HI+ V V + S G+D V L ++ H +V + +
Sbjct: 231 LSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPT 290
Query: 790 GNIFITGSQDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTF 848
++ +T S+D T W+V + T++ + ++T D + L
Sbjct: 291 IDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDL 350
Query: 849 ITGTYLHPLKRHKAKVK 865
+ G L HK V+
Sbjct: 351 VAGKTRVTLTNHKKSVR 367
Score = 58.0 bits (134), Expect = 2e-07
Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 1/128 (0%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H + C A+ +Q VTGS D ++K+W L GKL L GH V V VS T +
Sbjct: 194 HLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVS-TRSPYL 252
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
S D + WD+ V + + + V+C+ D T IW+ +
Sbjct: 253 FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKA 312
Query: 1253 ALTSFSLH 1260
++ + S H
Sbjct: 313 SVHTLSGH 320
Score = 53.2 bits (122), Expect = 7e-06
Identities = 48/222 (21%), Positives = 83/222 (37%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R + + P Q V + ++W + S + GH ++ + V+ S YL + ED
Sbjct: 199 RCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGED 258
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
V WDL V H++ V + ++++ DS I + A V L
Sbjct: 259 KQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLS 318
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLL 835
H +V +V+ ITGS D T+ W++ T+T V +
Sbjct: 319 GHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTF 378
Query: 836 TLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVA 877
+ + F G+++ L H A + V D V+
Sbjct: 379 ASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVS 420
Score = 42.3 bits (95), Expect = 0.012
Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
Query: 1167 KLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVK 1226
KL +V+ GH V C+AV N+ V+GS D + +WD+ + V V
Sbjct: 186 KLYRVISGHLGWVRCIAVEPGNQW-FVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVI 244
Query: 1227 VTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHV 1261
V+ SC EDK + W+ + + + H+
Sbjct: 245 VSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHL 279
>AF044333-1|AAD09407.1| 514|Homo sapiens pleiotropic regulator 1
protein.
Length = 514
Score = 94.3 bits (224), Expect = 3e-18
Identities = 61/257 (23%), Positives = 112/257 (43%), Gaps = 11/257 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
+L ++GH+G + C+ P N ++GS DRT+ +W LA L+ GH S ++ +++
Sbjct: 195 KLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 254
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSGIVL---HSATGPSASIDVTLNMKYAVLSDGDNSVRI 1115
+ S + V W ++ V+ H +D+ + V D++ RI
Sbjct: 255 STRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARI 314
Query: 1116 WSLAGGDNSEDNRRSVS-HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVG 1174
W + ++ + ++S H + A ++TGS D ++++W L GK L
Sbjct: 315 WDV----RTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTN 370
Query: 1175 HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIA 1234
H V V + + T SGS D N+ W + + V DG +
Sbjct: 371 HKKSVRAVVLHPRHYT-FASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDG-VL 427
Query: 1235 VSCAEDKTLIIWETKRG 1251
VS A++ T+ +W+ + G
Sbjct: 428 VSGADNGTMHLWDWRTG 444
Score = 86.2 bits (204), Expect = 8e-16
Identities = 59/244 (24%), Positives = 110/244 (45%), Gaps = 11/244 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ C+ V Q +G A +++W L++ +L+ +L GHI + V S + + S E
Sbjct: 207 VRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGE 266
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D+ V W L N Y GH SA+ L + ++ R +W V + +H+
Sbjct: 267 DKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTL 326
Query: 1089 TGPSASIDVTLNMKYA----VLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTA 1144
+G + ++ T+ + A + D ++R+W L G + +H + + L
Sbjct: 327 SGHTNAV-ATVRCQAAEPQIITGSHDTTIRLWDLVAG---KTRVTLTNHKKSVRAVVLHP 382
Query: 1145 DSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
+GS D ++K WK G Q L GH+ I+ +++ + +VSG+ + + +W
Sbjct: 383 RHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIIN--TLTVNSDGVLVSGADNGTMHLW 439
Query: 1205 DINT 1208
D T
Sbjct: 440 DWRT 443
Score = 62.1 bits (144), Expect = 1e-08
Identities = 46/197 (23%), Positives = 80/197 (40%), Gaps = 3/197 (1%)
Query: 670 APSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK 729
AP+ PQ WH GH G + C+ V +Q+ +TGS D ++ +WDL + +K
Sbjct: 182 APTMPKPQ-WH-PPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLK 239
Query: 730 TKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQD 789
+ HI+ V V + S G+D V L ++ H +V + +
Sbjct: 240 LSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPT 299
Query: 790 GNIFITGSQDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTF 848
++ +T S+D T W+V + T++ + ++T D + L
Sbjct: 300 IDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDL 359
Query: 849 ITGTYLHPLKRHKAKVK 865
+ G L HK V+
Sbjct: 360 VAGKTRVTLTNHKKSVR 376
Score = 58.0 bits (134), Expect = 2e-07
Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 1/128 (0%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H + C A+ +Q VTGS D ++K+W L GKL L GH V V VS T +
Sbjct: 203 HLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVS-TRSPYL 261
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
S D + WD+ V + + + V+C+ D T IW+ +
Sbjct: 262 FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKA 321
Query: 1253 ALTSFSLH 1260
++ + S H
Sbjct: 322 SVHTLSGH 329
Score = 53.2 bits (122), Expect = 7e-06
Identities = 48/222 (21%), Positives = 83/222 (37%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R + + P Q V + ++W + S + GH ++ + V+ S YL + ED
Sbjct: 208 RCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGED 267
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
V WDL V H++ V + ++++ DS I + A V L
Sbjct: 268 KQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLS 327
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLL 835
H +V +V+ ITGS D T+ W++ T+T V +
Sbjct: 328 GHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTF 387
Query: 836 TLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVA 877
+ + F G+++ L H A + V D V+
Sbjct: 388 ASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVS 429
Score = 42.3 bits (95), Expect = 0.012
Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
Query: 1167 KLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVK 1226
KL +V+ GH V C+AV N+ V+GS D + +WD+ + V V
Sbjct: 195 KLYRVISGHLGWVRCIAVEPGNQW-FVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVI 253
Query: 1227 VTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHV 1261
V+ SC EDK + W+ + + + H+
Sbjct: 254 VSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHL 288
>AB209111-1|BAD92348.1| 487|Homo sapiens Notchless gene homolog
variant protein.
Length = 487
Score = 94.3 bits (224), Expect = 3e-18
Identities = 70/266 (26%), Positives = 110/266 (41%), Gaps = 3/266 (1%)
Query: 982 ASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNS 1041
AS G VR+W + R + L GH +TC+ + + LL S S+DRT+ VW+ D
Sbjct: 222 ASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLY-SASQDRTIKVWRAHDGV 280
Query: 1042 PSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD-SGIVLHSATGPSASIDVTLN 1100
T +GH + T+ + +D + V D G + + ++
Sbjct: 281 LCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGFLQELKERALSRYNLVRG 340
Query: 1101 MKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
L G + ++ + ++ + R H I + DS+ V + S D S+K+
Sbjct: 341 QGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKL 400
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W GK L GH V +A S ++ +VSGS D L VWD+
Sbjct: 401 WDGRTGKYLASLRGHVAAVYQIAWSADSRL-LVSGSSDSTLKVWDVKAQKLAMDLPGHAD 459
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIW 1246
+V V + DG S +DK L IW
Sbjct: 460 EVYAVDWSPDGQRVASGGKDKCLRIW 485
Score = 85.4 bits (202), Expect = 1e-15
Identities = 58/196 (29%), Positives = 86/196 (43%), Gaps = 13/196 (6%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R ++L GH + V FSP + SGS D TV W L+ +P T KGH + ++
Sbjct: 107 RCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISW 166
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSG------IVLHS--ATGPS-ASIDVTLNMKYAVLSDG 1109
DG++ S + + +W +G + HS TG S + +Y S
Sbjct: 167 SPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSK 226
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLS 1169
D SVRIW G R H + +TC D + + S D ++KVW+ G L
Sbjct: 227 DGSVRIWDTTAG---RCERILTGHTQSVTCLRWGGDGL-LYSASQDRTIKVWRAHDGVLC 282
Query: 1170 QVLVGHSDIVTCVAVS 1185
+ L GH V +A+S
Sbjct: 283 RTLQGHGHWVNTMALS 298
Score = 77.0 bits (181), Expect = 5e-13
Identities = 72/287 (25%), Positives = 123/287 (42%), Gaps = 19/287 (6%)
Query: 975 SRDGQLGASGCARGLVRVWQLSTHR-LQATLNGHIGHITCVTFSPNNL-----LVLSGSE 1028
S DG+ ASGC G + +W ST + + TL GH IT +++ P + V S S+
Sbjct: 167 SPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSK 226
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D +V +W GH+ ++ L DG S+ + R + VW G++ +
Sbjct: 227 DGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGL-LYSASQDRTIKVWRAHDGVLCRTL 285
Query: 1089 TGPSASID-VTLNMKYAV----LSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
G ++ + L+ YA+ + SV L G E R++S +
Sbjct: 286 QGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGF-LQELKERALSRYNLVR----G 340
Query: 1144 ADSQHVVTGSMDMSLKVWK-LDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLI 1202
+ +V+GS D +L +W + K + GH ++ V S ++ V S S+D ++
Sbjct: 341 QGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRI-VASASFDKSIK 399
Query: 1203 VWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
+WD T V + + D + VS + D TL +W+ K
Sbjct: 400 LWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVK 446
Score = 57.6 bits (133), Expect = 3e-07
Identities = 36/144 (25%), Positives = 69/144 (47%), Gaps = 7/144 (4%)
Query: 1023 VLSGSEDRTVVVWQLADNSPSLT-YKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDS 1081
++SGS+D T+ +W A++ LT GH + I +L D R S+ +++ +W +
Sbjct: 346 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 405
Query: 1082 GIVLHSATGPSAS---IDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERIT 1138
G L S G A+ I + + + V D+++++W + + D HA+ +
Sbjct: 406 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMD---LPGHADEVY 462
Query: 1139 CFALTADSQHVVTGSMDMSLKVWK 1162
+ D Q V +G D L++W+
Sbjct: 463 AVDWSPDGQRVASGGKDKCLRIWR 486
Score = 57.6 bits (133), Expect = 3e-07
Identities = 26/103 (25%), Positives = 53/103 (51%)
Query: 975 SRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVV 1034
S D ++ AS +++W T + A+L GH+ + + +S ++ L++SGS D T+ V
Sbjct: 383 SPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKV 442
Query: 1035 WQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
W + ++ GH+ + + DG+R S + + + +W
Sbjct: 443 WDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 485
Score = 56.8 bits (131), Expect = 5e-07
Identities = 61/240 (25%), Positives = 97/240 (40%), Gaps = 9/240 (3%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
++CL DG L ++ R ++VW+ L TL GH + + S + L E
Sbjct: 251 VTCLRWGGDGLLYSASQDR-TIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFE 309
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWL-VDSGIVLHS 1087
V K + + L+ R +S + +W + L
Sbjct: 310 PAEASVNPQDLQGFLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTR 369
Query: 1088 ATGPSASIDVTL---NMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTA 1144
TG A I+ L + + + D S+++W G R H + A +A
Sbjct: 370 MTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLR---GHVAAVYQIAWSA 426
Query: 1145 DSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
DS+ +V+GS D +LKVW + KL+ L GH+D V V S + +V SG D L +W
Sbjct: 427 DSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWS-PDGQRVASGGKDKCLRIW 485
Score = 56.0 bits (129), Expect = 9e-07
Identities = 69/297 (23%), Positives = 114/297 (38%), Gaps = 15/297 (5%)
Query: 975 SRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVV 1034
S G+ ASG VR W LST T GH + +++SP+ + SG ++ +++
Sbjct: 125 SPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILL 184
Query: 1035 WQLADNSP-SLTYKGHSSAI-----QTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
W + T GHS I + L + R SS + +V +W +G
Sbjct: 185 WDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERIL 244
Query: 1089 TGPSASIDVTLNMKYAVL--SDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
TG + S+ +L + D ++++W G R H + AL+ D
Sbjct: 245 TGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLC---RTLQGHGHWVNTMALSTD- 300
Query: 1147 QHVVTGSMD-MSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ TG+ + V D Q L + + V ++VSGS D L +W
Sbjct: 301 YALRTGAFEPAEASVNPQDLQGFLQELKERA-LSRYNLVRGQGPERLVSGSDDFTLFLWS 359
Query: 1206 -INTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHV 1261
+ V + D I S + DK++ +W+ + G L S HV
Sbjct: 360 PAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHV 416
Score = 48.0 bits (109), Expect = 2e-04
Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 1/129 (0%)
Query: 678 LWHIMSNSKVHT-FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
LW + K T GH I + + +S+ + + S D S+ +WD T + H+
Sbjct: 357 LWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHV 416
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A V +A + L++SG DS + + + L L H V +V DG +G
Sbjct: 417 AAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASG 476
Query: 797 SQDGTVCTW 805
+D + W
Sbjct: 477 GKDKCLRIW 485
Score = 44.4 bits (100), Expect = 0.003
Identities = 19/62 (30%), Positives = 33/62 (53%)
Query: 975 SRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVV 1034
S D +L SG + ++VW + +L L GH + V +SP+ V SG +D+ + +
Sbjct: 425 SADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRI 484
Query: 1035 WQ 1036
W+
Sbjct: 485 WR 486
Score = 43.2 bits (97), Expect = 0.007
Identities = 37/162 (22%), Positives = 69/162 (42%), Gaps = 7/162 (4%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+P+G++L + W + + + T KGH +L + + + + L +G ++ +++
Sbjct: 125 SPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILL 184
Query: 721 WDLHT-LAVKTKILEHIAPVLCVA-----AIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
WD T V + H + ++ A V S D +V I G L
Sbjct: 185 WDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERIL 244
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV 816
H SVT ++ DG ++ + SQD T+ W + L T+
Sbjct: 245 TGHTQSVTCLRWGGDGLLY-SASQDRTIKVWRAHDGVLCRTL 285
Score = 39.5 bits (88), Expect = 0.087
Identities = 46/240 (19%), Positives = 96/240 (40%), Gaps = 3/240 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L P +++ + G ++W + GH+ S+ C+ + L + S+D +
Sbjct: 212 LHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRT 270
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ VW H + + H V +A + +L + + + + +L
Sbjct: 271 IKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGFLQELKER 330
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWN-VENFTLLSTVTA-GVPIHIFDVTDDNVFLL 835
S ++ Q ++GS D T+ W+ E+ L+ +T I+ + D+ +
Sbjct: 331 ALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVA 390
Query: 836 TLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQL 895
+ D + L TG YL L+ H A V + DS + G +D + ++ + + +L
Sbjct: 391 SASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKL 450
Score = 39.1 bits (87), Expect = 0.11
Identities = 21/86 (24%), Positives = 42/86 (48%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
+LW + + + +GH ++ + + +S+ L++GS D+++ VWD+ + + H
Sbjct: 399 KLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHA 458
Query: 737 APVLCVAAIVNRSLVISGGDDSAVII 762
V V + V SGG D + I
Sbjct: 459 DEVYAVDWSPDGQRVASGGKDKCLRI 484
Score = 38.3 bits (85), Expect = 0.20
Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 1172 LVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDG 1231
L GHS+ V VA S T K + SGS D + WD++T V + + DG
Sbjct: 112 LEGHSEAVISVAFSPTGK-YLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDG 170
Query: 1232 TIAVSCAEDKTLIIWETKRG 1251
S ++ +++W+ G
Sbjct: 171 KKLASGCKNGQILLWDPSTG 190
Score = 36.3 bits (80), Expect = 0.81
Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 6/124 (4%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
+ +GHS +++ + + +YL +GS DT+V WDL T H VL ++ +
Sbjct: 111 SLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDG 170
Query: 749 SLVISGGDDSAVIITSLVDGALVTK-LDHHRGSVTSVK-----VIQDGNIFITGSQDGTV 802
+ SG + +++ G V + L H +T + + + S+DG+V
Sbjct: 171 KKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSV 230
Query: 803 CTWN 806
W+
Sbjct: 231 RIWD 234
Score = 33.5 bits (73), Expect = 5.7
Identities = 26/125 (20%), Positives = 53/125 (42%), Gaps = 7/125 (5%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H+E + A + +++ +GS D +++ W L GH V ++ S K ++
Sbjct: 115 HSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK-KL 173
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXK-VTCVK-----VTGDGTIAVSCAEDKTLIIW 1246
SG + +++WD +T K +T + + S ++D ++ IW
Sbjct: 174 ASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIW 233
Query: 1247 ETKRG 1251
+T G
Sbjct: 234 DTTAG 238
>BC012075-1|AAH12075.1| 485|Homo sapiens notchless homolog 1
(Drosophila) protein.
Length = 485
Score = 93.5 bits (222), Expect = 5e-18
Identities = 70/266 (26%), Positives = 110/266 (41%), Gaps = 3/266 (1%)
Query: 982 ASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNS 1041
AS G VR+W + R + L GH +TC+ + + LL S S+DRT+ VW+ D
Sbjct: 220 ASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLY-SASQDRTIKVWRAHDGV 278
Query: 1042 PSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD-SGIVLHSATGPSASIDVTLN 1100
T +GH + T+ + +D + V D G + + ++
Sbjct: 279 LCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRG 338
Query: 1101 MKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
L G + ++ + ++ + R H I + DS+ V + S D S+K+
Sbjct: 339 QGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKL 398
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W GK L GH V +A S ++ +VSGS D L VWD+
Sbjct: 399 WDGRTGKYLASLRGHVAAVYQIAWSADSRL-LVSGSSDSTLKVWDVKAQKLAMDLPGHAD 457
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIW 1246
+V V + DG S +DK L IW
Sbjct: 458 EVYAVDWSPDGQRVASGGKDKCLRIW 483
Score = 85.4 bits (202), Expect = 1e-15
Identities = 58/196 (29%), Positives = 86/196 (43%), Gaps = 13/196 (6%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R ++L GH + V FSP + SGS D TV W L+ +P T KGH + ++
Sbjct: 105 RCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISW 164
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSG------IVLHS--ATGPS-ASIDVTLNMKYAVLSDG 1109
DG++ S + + +W +G + HS TG S + +Y S
Sbjct: 165 SPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSK 224
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLS 1169
D SVRIW G R H + +TC D + + S D ++KVW+ G L
Sbjct: 225 DGSVRIWDTTAG---RCERILTGHTQSVTCLRWGGDGL-LYSASQDRTIKVWRAHDGVLC 280
Query: 1170 QVLVGHSDIVTCVAVS 1185
+ L GH V +A+S
Sbjct: 281 RTLQGHGHWVNTMALS 296
Score = 78.2 bits (184), Expect = 2e-13
Identities = 72/287 (25%), Positives = 123/287 (42%), Gaps = 19/287 (6%)
Query: 975 SRDGQLGASGCARGLVRVWQLSTHR-LQATLNGHIGHITCVTFSPNNL-----LVLSGSE 1028
S DG+ ASGC G + +W ST + + TL GH IT +++ P + V S S+
Sbjct: 165 SPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSK 224
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D +V +W GH+ ++ L DG S+ + R + VW G++ +
Sbjct: 225 DGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGL-LYSASQDRTIKVWRAHDGVLCRTL 283
Query: 1089 TGPSASID-VTLNMKYAV----LSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
G ++ + L+ YA+ + SV L G E R++S +
Sbjct: 284 QGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGS-LQELKERALSRYNLVR----G 338
Query: 1144 ADSQHVVTGSMDMSLKVWK-LDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLI 1202
+ +V+GS D +L +W + K + GH ++ V S ++ V S S+D ++
Sbjct: 339 QGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRI-VASASFDKSIK 397
Query: 1203 VWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
+WD T V + + D + VS + D TL +W+ K
Sbjct: 398 LWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVK 444
Score = 58.8 bits (136), Expect = 1e-07
Identities = 64/241 (26%), Positives = 100/241 (41%), Gaps = 11/241 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
++CL DG L ++ R ++VW+ L TL GH + + S + L E
Sbjct: 249 VTCLRWGGDGLLYSASQDR-TIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFE 307
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDG-RRAMSSDRARNVHVWL-VDSGIVLH 1086
V D SL + + L+ G R +S + +W + L
Sbjct: 308 PAEASV-NPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLT 366
Query: 1087 SATGPSASIDVTL---NMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
TG A I+ L + + + D S+++W G R H + A +
Sbjct: 367 RMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLR---GHVAAVYQIAWS 423
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIV 1203
ADS+ +V+GS D +LKVW + KL+ L GH+D V V S + +V SG D L +
Sbjct: 424 ADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWS-PDGQRVASGGKDKCLRI 482
Query: 1204 W 1204
W
Sbjct: 483 W 483
Score = 57.6 bits (133), Expect = 3e-07
Identities = 36/144 (25%), Positives = 69/144 (47%), Gaps = 7/144 (4%)
Query: 1023 VLSGSEDRTVVVWQLADNSPSLT-YKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDS 1081
++SGS+D T+ +W A++ LT GH + I +L D R S+ +++ +W +
Sbjct: 344 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 403
Query: 1082 GIVLHSATGPSAS---IDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERIT 1138
G L S G A+ I + + + V D+++++W + + D HA+ +
Sbjct: 404 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMD---LPGHADEVY 460
Query: 1139 CFALTADSQHVVTGSMDMSLKVWK 1162
+ D Q V +G D L++W+
Sbjct: 461 AVDWSPDGQRVASGGKDKCLRIWR 484
Score = 56.8 bits (131), Expect = 5e-07
Identities = 69/301 (22%), Positives = 118/301 (39%), Gaps = 23/301 (7%)
Query: 975 SRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVV 1034
S G+ ASG VR W LST T GH + +++SP+ + SG ++ +++
Sbjct: 123 SPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILL 182
Query: 1035 WQLADNSP-SLTYKGHSSAI-----QTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
W + T GHS I + L + R SS + +V +W +G
Sbjct: 183 WDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERIL 242
Query: 1089 TGPSASIDVTLNMKYAVL--SDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
TG + S+ +L + D ++++W G R H + AL+ D
Sbjct: 243 TGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLC---RTLQGHGHWVNTMALSTD- 298
Query: 1147 QHVVTGSM---DMSLKVWKLDGG--KLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNL 1201
+ TG+ + S+ L G +L + + ++V ++VSGS D L
Sbjct: 299 YALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRG-----QGPERLVSGSDDFTL 353
Query: 1202 IVWD-INTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
+W + V + D I S + DK++ +W+ + G L S H
Sbjct: 354 FLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGH 413
Query: 1261 V 1261
V
Sbjct: 414 V 414
Score = 48.0 bits (109), Expect = 2e-04
Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 1/129 (0%)
Query: 678 LWHIMSNSKVHT-FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
LW + K T GH I + + +S+ + + S D S+ +WD T + H+
Sbjct: 355 LWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHV 414
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A V +A + L++SG DS + + + L L H V +V DG +G
Sbjct: 415 AAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASG 474
Query: 797 SQDGTVCTW 805
+D + W
Sbjct: 475 GKDKCLRIW 483
Score = 44.4 bits (100), Expect = 0.003
Identities = 19/62 (30%), Positives = 33/62 (53%)
Query: 975 SRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVV 1034
S D +L SG + ++VW + +L L GH + V +SP+ V SG +D+ + +
Sbjct: 423 SADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRI 482
Query: 1035 WQ 1036
W+
Sbjct: 483 WR 484
Score = 43.2 bits (97), Expect = 0.007
Identities = 37/162 (22%), Positives = 69/162 (42%), Gaps = 7/162 (4%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+P+G++L + W + + + T KGH +L + + + + L +G ++ +++
Sbjct: 123 SPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILL 182
Query: 721 WDLHT-LAVKTKILEHIAPVLCVA-----AIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
WD T V + H + ++ A V S D +V I G L
Sbjct: 183 WDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERIL 242
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV 816
H SVT ++ DG ++ + SQD T+ W + L T+
Sbjct: 243 TGHTQSVTCLRWGGDGLLY-SASQDRTIKVWRAHDGVLCRTL 283
Score = 39.1 bits (87), Expect = 0.11
Identities = 21/86 (24%), Positives = 42/86 (48%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
+LW + + + +GH ++ + + +S+ L++GS D+++ VWD+ + + H
Sbjct: 397 KLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHA 456
Query: 737 APVLCVAAIVNRSLVISGGDDSAVII 762
V V + V SGG D + I
Sbjct: 457 DEVYAVDWSPDGQRVASGGKDKCLRI 482
Score = 38.7 bits (86), Expect = 0.15
Identities = 46/240 (19%), Positives = 96/240 (40%), Gaps = 3/240 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L P +++ + G ++W + GH+ S+ C+ + L + S+D +
Sbjct: 210 LHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRT 268
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ VW H + + H V +A + +L + + + + +L
Sbjct: 269 IKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKER 328
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWN-VENFTLLSTVTA-GVPIHIFDVTDDNVFLL 835
S ++ Q ++GS D T+ W+ E+ L+ +T I+ + D+ +
Sbjct: 329 ALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVA 388
Query: 836 TLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQL 895
+ D + L TG YL L+ H A V + DS + G +D + ++ + + +L
Sbjct: 389 SASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKL 448
Score = 38.3 bits (85), Expect = 0.20
Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 1172 LVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDG 1231
L GHS+ V VA S T K + SGS D + WD++T V + + DG
Sbjct: 110 LEGHSEAVISVAFSPTGK-YLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDG 168
Query: 1232 TIAVSCAEDKTLIIWETKRG 1251
S ++ +++W+ G
Sbjct: 169 KKLASGCKNGQILLWDPSTG 188
Score = 36.3 bits (80), Expect = 0.81
Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 6/124 (4%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
+ +GHS +++ + + +YL +GS DT+V WDL T H VL ++ +
Sbjct: 109 SLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDG 168
Query: 749 SLVISGGDDSAVIITSLVDGALVTK-LDHHRGSVTSVK-----VIQDGNIFITGSQDGTV 802
+ SG + +++ G V + L H +T + + + S+DG+V
Sbjct: 169 KKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSV 228
Query: 803 CTWN 806
W+
Sbjct: 229 RIWD 232
Score = 33.5 bits (73), Expect = 5.7
Identities = 26/125 (20%), Positives = 53/125 (42%), Gaps = 7/125 (5%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H+E + A + +++ +GS D +++ W L GH V ++ S K ++
Sbjct: 113 HSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK-KL 171
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXK-VTCVK-----VTGDGTIAVSCAEDKTLIIW 1246
SG + +++WD +T K +T + + S ++D ++ IW
Sbjct: 172 ASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIW 231
Query: 1247 ETKRG 1251
+T G
Sbjct: 232 DTTAG 236
>BC002884-1|AAH02884.2| 484|Homo sapiens NLE1 protein protein.
Length = 484
Score = 93.5 bits (222), Expect = 5e-18
Identities = 70/266 (26%), Positives = 110/266 (41%), Gaps = 3/266 (1%)
Query: 982 ASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNS 1041
AS G VR+W + R + L GH +TC+ + + LL S S+DRT+ VW+ D
Sbjct: 219 ASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLY-SASQDRTIKVWRAHDGV 277
Query: 1042 PSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD-SGIVLHSATGPSASIDVTLN 1100
T +GH + T+ + +D + V D G + + ++
Sbjct: 278 LCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRG 337
Query: 1101 MKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
L G + ++ + ++ + R H I + DS+ V + S D S+K+
Sbjct: 338 QGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKL 397
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W GK L GH V +A S ++ +VSGS D L VWD+
Sbjct: 398 WDGRTGKYLASLRGHVAAVYQIAWSADSRL-LVSGSSDSTLKVWDVKAQKLAMDLPGHAD 456
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIW 1246
+V V + DG S +DK L IW
Sbjct: 457 EVYAVDWSPDGQRVASGGKDKCLRIW 482
Score = 85.4 bits (202), Expect = 1e-15
Identities = 58/196 (29%), Positives = 86/196 (43%), Gaps = 13/196 (6%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R ++L GH + V FSP + SGS D TV W L+ +P T KGH + ++
Sbjct: 104 RCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISW 163
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSG------IVLHS--ATGPS-ASIDVTLNMKYAVLSDG 1109
DG++ S + + +W +G + HS TG S + +Y S
Sbjct: 164 SPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSK 223
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLS 1169
D SVRIW G R H + +TC D + + S D ++KVW+ G L
Sbjct: 224 DGSVRIWDTTAG---RCERILTGHTQSVTCLRWGGDGL-LYSASQDRTIKVWRAHDGVLC 279
Query: 1170 QVLVGHSDIVTCVAVS 1185
+ L GH V +A+S
Sbjct: 280 RTLQGHGHWVNTMALS 295
Score = 78.2 bits (184), Expect = 2e-13
Identities = 72/287 (25%), Positives = 123/287 (42%), Gaps = 19/287 (6%)
Query: 975 SRDGQLGASGCARGLVRVWQLSTHR-LQATLNGHIGHITCVTFSPNNL-----LVLSGSE 1028
S DG+ ASGC G + +W ST + + TL GH IT +++ P + V S S+
Sbjct: 164 SPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSK 223
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D +V +W GH+ ++ L DG S+ + R + VW G++ +
Sbjct: 224 DGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGL-LYSASQDRTIKVWRAHDGVLCRTL 282
Query: 1089 TGPSASID-VTLNMKYAV----LSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
G ++ + L+ YA+ + SV L G E R++S +
Sbjct: 283 QGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGS-LQELKERALSRYNLVR----G 337
Query: 1144 ADSQHVVTGSMDMSLKVWK-LDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLI 1202
+ +V+GS D +L +W + K + GH ++ V S ++ V S S+D ++
Sbjct: 338 QGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRI-VASASFDKSIK 396
Query: 1203 VWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
+WD T V + + D + VS + D TL +W+ K
Sbjct: 397 LWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVK 443
Score = 58.8 bits (136), Expect = 1e-07
Identities = 64/241 (26%), Positives = 100/241 (41%), Gaps = 11/241 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
++CL DG L ++ R ++VW+ L TL GH + + S + L E
Sbjct: 248 VTCLRWGGDGLLYSASQDR-TIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFE 306
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDG-RRAMSSDRARNVHVWL-VDSGIVLH 1086
V D SL + + L+ G R +S + +W + L
Sbjct: 307 PAEASV-NPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLT 365
Query: 1087 SATGPSASIDVTL---NMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
TG A I+ L + + + D S+++W G R H + A +
Sbjct: 366 RMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLR---GHVAAVYQIAWS 422
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIV 1203
ADS+ +V+GS D +LKVW + KL+ L GH+D V V S + +V SG D L +
Sbjct: 423 ADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWS-PDGQRVASGGKDKCLRI 481
Query: 1204 W 1204
W
Sbjct: 482 W 482
Score = 57.6 bits (133), Expect = 3e-07
Identities = 36/144 (25%), Positives = 69/144 (47%), Gaps = 7/144 (4%)
Query: 1023 VLSGSEDRTVVVWQLADNSPSLT-YKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDS 1081
++SGS+D T+ +W A++ LT GH + I +L D R S+ +++ +W +
Sbjct: 343 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 402
Query: 1082 GIVLHSATGPSAS---IDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERIT 1138
G L S G A+ I + + + V D+++++W + + D HA+ +
Sbjct: 403 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMD---LPGHADEVY 459
Query: 1139 CFALTADSQHVVTGSMDMSLKVWK 1162
+ D Q V +G D L++W+
Sbjct: 460 AVDWSPDGQRVASGGKDKCLRIWR 483
Score = 56.8 bits (131), Expect = 5e-07
Identities = 69/301 (22%), Positives = 118/301 (39%), Gaps = 23/301 (7%)
Query: 975 SRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVV 1034
S G+ ASG VR W LST T GH + +++SP+ + SG ++ +++
Sbjct: 122 SPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILL 181
Query: 1035 WQLADNSP-SLTYKGHSSAI-----QTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
W + T GHS I + L + R SS + +V +W +G
Sbjct: 182 WDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERIL 241
Query: 1089 TGPSASIDVTLNMKYAVL--SDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
TG + S+ +L + D ++++W G R H + AL+ D
Sbjct: 242 TGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLC---RTLQGHGHWVNTMALSTD- 297
Query: 1147 QHVVTGSM---DMSLKVWKLDGG--KLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNL 1201
+ TG+ + S+ L G +L + + ++V ++VSGS D L
Sbjct: 298 YALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRG-----QGPERLVSGSDDFTL 352
Query: 1202 IVWD-INTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
+W + V + D I S + DK++ +W+ + G L S H
Sbjct: 353 FLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGH 412
Query: 1261 V 1261
V
Sbjct: 413 V 413
Score = 48.0 bits (109), Expect = 2e-04
Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 1/129 (0%)
Query: 678 LWHIMSNSKVHT-FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
LW + K T GH I + + +S+ + + S D S+ +WD T + H+
Sbjct: 354 LWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHV 413
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A V +A + L++SG DS + + + L L H V +V DG +G
Sbjct: 414 AAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASG 473
Query: 797 SQDGTVCTW 805
+D + W
Sbjct: 474 GKDKCLRIW 482
Score = 44.4 bits (100), Expect = 0.003
Identities = 19/62 (30%), Positives = 33/62 (53%)
Query: 975 SRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVV 1034
S D +L SG + ++VW + +L L GH + V +SP+ V SG +D+ + +
Sbjct: 422 SADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRI 481
Query: 1035 WQ 1036
W+
Sbjct: 482 WR 483
Score = 43.2 bits (97), Expect = 0.007
Identities = 37/162 (22%), Positives = 69/162 (42%), Gaps = 7/162 (4%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+P+G++L + W + + + T KGH +L + + + + L +G ++ +++
Sbjct: 122 SPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILL 181
Query: 721 WDLHT-LAVKTKILEHIAPVLCVA-----AIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
WD T V + H + ++ A V S D +V I G L
Sbjct: 182 WDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERIL 241
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV 816
H SVT ++ DG ++ + SQD T+ W + L T+
Sbjct: 242 TGHTQSVTCLRWGGDGLLY-SASQDRTIKVWRAHDGVLCRTL 282
Score = 39.1 bits (87), Expect = 0.11
Identities = 21/86 (24%), Positives = 42/86 (48%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
+LW + + + +GH ++ + + +S+ L++GS D+++ VWD+ + + H
Sbjct: 396 KLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHA 455
Query: 737 APVLCVAAIVNRSLVISGGDDSAVII 762
V V + V SGG D + I
Sbjct: 456 DEVYAVDWSPDGQRVASGGKDKCLRI 481
Score = 38.7 bits (86), Expect = 0.15
Identities = 46/240 (19%), Positives = 96/240 (40%), Gaps = 3/240 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L P +++ + G ++W + GH+ S+ C+ + L + S+D +
Sbjct: 209 LHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRT 267
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ VW H + + H V +A + +L + + + + +L
Sbjct: 268 IKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKER 327
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWN-VENFTLLSTVTA-GVPIHIFDVTDDNVFLL 835
S ++ Q ++GS D T+ W+ E+ L+ +T I+ + D+ +
Sbjct: 328 ALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVA 387
Query: 836 TLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQL 895
+ D + L TG YL L+ H A V + DS + G +D + ++ + + +L
Sbjct: 388 SASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKL 447
Score = 38.3 bits (85), Expect = 0.20
Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 1172 LVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDG 1231
L GHS+ V VA S T K + SGS D + WD++T V + + DG
Sbjct: 109 LEGHSEAVISVAFSPTGK-YLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDG 167
Query: 1232 TIAVSCAEDKTLIIWETKRG 1251
S ++ +++W+ G
Sbjct: 168 KKLASGCKNGQILLWDPSTG 187
Score = 36.3 bits (80), Expect = 0.81
Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 6/124 (4%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
+ +GHS +++ + + +YL +GS DT+V WDL T H VL ++ +
Sbjct: 108 SLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDG 167
Query: 749 SLVISGGDDSAVIITSLVDGALVTK-LDHHRGSVTSVK-----VIQDGNIFITGSQDGTV 802
+ SG + +++ G V + L H +T + + + S+DG+V
Sbjct: 168 KKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSV 227
Query: 803 CTWN 806
W+
Sbjct: 228 RIWD 231
Score = 33.5 bits (73), Expect = 5.7
Identities = 26/125 (20%), Positives = 53/125 (42%), Gaps = 7/125 (5%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H+E + A + +++ +GS D +++ W L GH V ++ S K ++
Sbjct: 112 HSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK-KL 170
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXK-VTCVK-----VTGDGTIAVSCAEDKTLIIW 1246
SG + +++WD +T K +T + + S ++D ++ IW
Sbjct: 171 ASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIW 230
Query: 1247 ETKRG 1251
+T G
Sbjct: 231 DTTAG 235
>AK001320-1|BAA91621.1| 485|Homo sapiens protein ( Homo sapiens cDNA
FLJ10458 fis, clone NT2RP1001457, highly similar to Homo
sapiens partial mRNA for beta-transducin family protein.
).
Length = 485
Score = 93.5 bits (222), Expect = 5e-18
Identities = 70/266 (26%), Positives = 110/266 (41%), Gaps = 3/266 (1%)
Query: 982 ASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNS 1041
AS G VR+W + R + L GH +TC+ + + LL S S+DRT+ VW+ D
Sbjct: 220 ASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLY-SASQDRTIKVWRAHDGV 278
Query: 1042 PSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD-SGIVLHSATGPSASIDVTLN 1100
T +GH + T+ + +D + V D G + + ++
Sbjct: 279 LCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRG 338
Query: 1101 MKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
L G + ++ + ++ + R H I + DS+ V + S D S+K+
Sbjct: 339 QGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKL 398
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W GK L GH V +A S ++ +VSGS D L VWD+
Sbjct: 399 WDGRTGKYLASLRGHVAAVYQIAWSADSRL-LVSGSSDSTLKVWDVKAQKLAMDLPGHAD 457
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIW 1246
+V V + DG S +DK L IW
Sbjct: 458 EVYAVDWSPDGQRVASGGKDKCLRIW 483
Score = 85.4 bits (202), Expect = 1e-15
Identities = 58/196 (29%), Positives = 86/196 (43%), Gaps = 13/196 (6%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R ++L GH + V FSP + SGS D TV W L+ +P T KGH + ++
Sbjct: 105 RCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISW 164
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSG------IVLHS--ATGPS-ASIDVTLNMKYAVLSDG 1109
DG++ S + + +W +G + HS TG S + +Y S
Sbjct: 165 SPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSK 224
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLS 1169
D SVRIW G R H + +TC D + + S D ++KVW+ G L
Sbjct: 225 DGSVRIWDTTAG---RCERILTGHTQSVTCLRWGGDGL-LYSASQDRTIKVWRAHDGVLC 280
Query: 1170 QVLVGHSDIVTCVAVS 1185
+ L GH V +A+S
Sbjct: 281 RTLQGHGHWVNTMALS 296
Score = 78.2 bits (184), Expect = 2e-13
Identities = 72/287 (25%), Positives = 123/287 (42%), Gaps = 19/287 (6%)
Query: 975 SRDGQLGASGCARGLVRVWQLSTHR-LQATLNGHIGHITCVTFSPNNL-----LVLSGSE 1028
S DG+ ASGC G + +W ST + + TL GH IT +++ P + V S S+
Sbjct: 165 SPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSK 224
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D +V +W GH+ ++ L DG S+ + R + VW G++ +
Sbjct: 225 DGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGL-LYSASQDRTIKVWRAHDGVLCRTL 283
Query: 1089 TGPSASID-VTLNMKYAV----LSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
G ++ + L+ YA+ + SV L G E R++S +
Sbjct: 284 QGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGS-LQELKERALSRYNLVR----G 338
Query: 1144 ADSQHVVTGSMDMSLKVWK-LDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLI 1202
+ +V+GS D +L +W + K + GH ++ V S ++ V S S+D ++
Sbjct: 339 QGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRI-VASASFDKSIK 397
Query: 1203 VWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
+WD T V + + D + VS + D TL +W+ K
Sbjct: 398 LWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVK 444
Score = 58.8 bits (136), Expect = 1e-07
Identities = 64/241 (26%), Positives = 100/241 (41%), Gaps = 11/241 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
++CL DG L ++ R ++VW+ L TL GH + + S + L E
Sbjct: 249 VTCLRWGGDGLLYSASQDR-TIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFE 307
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDG-RRAMSSDRARNVHVWL-VDSGIVLH 1086
V D SL + + L+ G R +S + +W + L
Sbjct: 308 PAEASV-NPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLT 366
Query: 1087 SATGPSASIDVTL---NMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
TG A I+ L + + + D S+++W G R H + A +
Sbjct: 367 RMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLR---GHVAAVYQIAWS 423
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIV 1203
ADS+ +V+GS D +LKVW + KL+ L GH+D V V S + +V SG D L +
Sbjct: 424 ADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWS-PDGQRVASGGKDKCLRI 482
Query: 1204 W 1204
W
Sbjct: 483 W 483
Score = 57.6 bits (133), Expect = 3e-07
Identities = 36/144 (25%), Positives = 69/144 (47%), Gaps = 7/144 (4%)
Query: 1023 VLSGSEDRTVVVWQLADNSPSLT-YKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDS 1081
++SGS+D T+ +W A++ LT GH + I +L D R S+ +++ +W +
Sbjct: 344 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 403
Query: 1082 GIVLHSATGPSAS---IDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERIT 1138
G L S G A+ I + + + V D+++++W + + D HA+ +
Sbjct: 404 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMD---LPGHADEVY 460
Query: 1139 CFALTADSQHVVTGSMDMSLKVWK 1162
+ D Q V +G D L++W+
Sbjct: 461 AVDWSPDGQRVASGGKDKCLRIWR 484
Score = 56.8 bits (131), Expect = 5e-07
Identities = 69/301 (22%), Positives = 118/301 (39%), Gaps = 23/301 (7%)
Query: 975 SRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVV 1034
S G+ ASG VR W LST T GH + +++SP+ + SG ++ +++
Sbjct: 123 SPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILL 182
Query: 1035 WQLADNSP-SLTYKGHSSAI-----QTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
W + T GHS I + L + R SS + +V +W +G
Sbjct: 183 WDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERIL 242
Query: 1089 TGPSASIDVTLNMKYAVL--SDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
TG + S+ +L + D ++++W G R H + AL+ D
Sbjct: 243 TGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLC---RTLQGHGHWVNTMALSTD- 298
Query: 1147 QHVVTGSM---DMSLKVWKLDGG--KLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNL 1201
+ TG+ + S+ L G +L + + ++V ++VSGS D L
Sbjct: 299 YALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRG-----QGPERLVSGSDDFTL 353
Query: 1202 IVWD-INTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
+W + V + D I S + DK++ +W+ + G L S H
Sbjct: 354 FLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGH 413
Query: 1261 V 1261
V
Sbjct: 414 V 414
Score = 48.0 bits (109), Expect = 2e-04
Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 1/129 (0%)
Query: 678 LWHIMSNSKVHT-FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
LW + K T GH I + + +S+ + + S D S+ +WD T + H+
Sbjct: 355 LWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHV 414
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A V +A + L++SG DS + + + L L H V +V DG +G
Sbjct: 415 AAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASG 474
Query: 797 SQDGTVCTW 805
+D + W
Sbjct: 475 GKDKCLRIW 483
Score = 44.4 bits (100), Expect = 0.003
Identities = 19/62 (30%), Positives = 33/62 (53%)
Query: 975 SRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVV 1034
S D +L SG + ++VW + +L L GH + V +SP+ V SG +D+ + +
Sbjct: 423 SADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRI 482
Query: 1035 WQ 1036
W+
Sbjct: 483 WR 484
Score = 43.2 bits (97), Expect = 0.007
Identities = 37/162 (22%), Positives = 69/162 (42%), Gaps = 7/162 (4%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+P+G++L + W + + + T KGH +L + + + + L +G ++ +++
Sbjct: 123 SPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILL 182
Query: 721 WDLHT-LAVKTKILEHIAPVLCVA-----AIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
WD T V + H + ++ A V S D +V I G L
Sbjct: 183 WDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERIL 242
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV 816
H SVT ++ DG ++ + SQD T+ W + L T+
Sbjct: 243 TGHTQSVTCLRWGGDGLLY-SASQDRTIKVWRAHDGVLCRTL 283
Score = 39.1 bits (87), Expect = 0.11
Identities = 21/86 (24%), Positives = 42/86 (48%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
+LW + + + +GH ++ + + +S+ L++GS D+++ VWD+ + + H
Sbjct: 397 KLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHA 456
Query: 737 APVLCVAAIVNRSLVISGGDDSAVII 762
V V + V SGG D + I
Sbjct: 457 DEVYAVDWSPDGQRVASGGKDKCLRI 482
Score = 38.7 bits (86), Expect = 0.15
Identities = 46/240 (19%), Positives = 96/240 (40%), Gaps = 3/240 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L P +++ + G ++W + GH+ S+ C+ + L + S+D +
Sbjct: 210 LHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRT 268
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ VW H + + H V +A + +L + + + + +L
Sbjct: 269 IKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKER 328
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWN-VENFTLLSTVTA-GVPIHIFDVTDDNVFLL 835
S ++ Q ++GS D T+ W+ E+ L+ +T I+ + D+ +
Sbjct: 329 ALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVA 388
Query: 836 TLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQL 895
+ D + L TG YL L+ H A V + DS + G +D + ++ + + +L
Sbjct: 389 SASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKL 448
Score = 38.3 bits (85), Expect = 0.20
Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 1172 LVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDG 1231
L GHS+ V VA S T K + SGS D + WD++T V + + DG
Sbjct: 110 LEGHSEAVISVAFSPTGK-YLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDG 168
Query: 1232 TIAVSCAEDKTLIIWETKRG 1251
S ++ +++W+ G
Sbjct: 169 KKLASGCKNGQILLWDPSTG 188
Score = 36.3 bits (80), Expect = 0.81
Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 6/124 (4%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
+ +GHS +++ + + +YL +GS DT+V WDL T H VL ++ +
Sbjct: 109 SLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDG 168
Query: 749 SLVISGGDDSAVIITSLVDGALVTK-LDHHRGSVTSVK-----VIQDGNIFITGSQDGTV 802
+ SG + +++ G V + L H +T + + + S+DG+V
Sbjct: 169 KKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSV 228
Query: 803 CTWN 806
W+
Sbjct: 229 RIWD 232
Score = 33.5 bits (73), Expect = 5.7
Identities = 26/125 (20%), Positives = 53/125 (42%), Gaps = 7/125 (5%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H+E + A + +++ +GS D +++ W L GH V ++ S K ++
Sbjct: 113 HSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK-KL 171
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXK-VTCVK-----VTGDGTIAVSCAEDKTLIIW 1246
SG + +++WD +T K +T + + S ++D ++ IW
Sbjct: 172 ASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIW 231
Query: 1247 ETKRG 1251
+T G
Sbjct: 232 DTTAG 236
>BC036377-1|AAH36377.1| 415|Homo sapiens WD repeat domain 69 protein.
Length = 415
Score = 90.6 bits (215), Expect = 4e-17
Identities = 63/270 (23%), Positives = 116/270 (42%), Gaps = 11/270 (4%)
Query: 982 ASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNS 1041
A+G ++W + T + T GH I C++F+P + LV +GS D T +W + +
Sbjct: 151 ATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGE 210
Query: 1042 PSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLN 1100
T +GHS+ I +L + G R ++ V VW D+G ++ G A I + N
Sbjct: 211 EVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFN 270
Query: 1101 MKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERI--TCFALTADSQHVVTGSMDM 1156
+++ G D + ++W N + H + I +CF T + + T S D
Sbjct: 271 WDCSLILTGSMDKTCKLWD---ATNGKCVATLTGHDDEILDSCFDYT--GKLIATASADG 325
Query: 1157 SLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXX 1216
+ +++ K L GH ++ ++ + +++GS D +WD T
Sbjct: 326 TARIFSAATRKCIAKLEGHEGEISKISFN-PQGNHLLTGSSDKTARIWDAQTGQCLQVLE 384
Query: 1217 XXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
++ G I ++ ++D T IW
Sbjct: 385 GHTDEIFSCAFNYKGNIVITGSKDNTCRIW 414
Score = 89.0 bits (211), Expect = 1e-16
Identities = 63/307 (20%), Positives = 125/307 (40%), Gaps = 8/307 (2%)
Query: 958 LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTF- 1016
L + ++ ++P++ + +++ G +G ++W ++ TL GH + + F
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFN 143
Query: 1017 SPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHV 1076
+P + +GS D+T +W + T++GH++ I L + +
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKL 203
Query: 1077 WLVDSGIVLHSATGPSAS-IDVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSH 1133
W + +G +++ G SA I ++ N + G D++V +W D + H
Sbjct: 204 WDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWD---ADTGRKVNILIGH 260
Query: 1134 AERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVV 1193
I+ + D ++TGSMD + K+W GK L GH D + T K +
Sbjct: 261 CAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKL-IA 319
Query: 1194 SGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLA 1253
+ S D ++ T +++ + G ++ + DKT IW+ + G
Sbjct: 320 TASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQC 379
Query: 1254 LTSFSLH 1260
L H
Sbjct: 380 LQVLEGH 386
Score = 84.2 bits (199), Expect = 3e-15
Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 3/223 (1%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
+LW + + HTF+GH+ I+C+ +S + TGS DT+ +WD+ + H
Sbjct: 160 KLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHS 219
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A ++ ++ + +I+G D V++ G V L H ++S D ++ +TG
Sbjct: 220 AEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTG 279
Query: 797 SQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDD--NVFLLTLQGDNELHLRTFITGTYL 854
S D T W+ N ++T+T G I D D + T D + + T +
Sbjct: 280 SMDKTCKLWDATNGKCVATLT-GHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCI 338
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
L+ H+ ++ + + G +D+ ++ + Q L+
Sbjct: 339 AKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQ 381
Score = 80.6 bits (190), Expect = 4e-14
Identities = 58/239 (24%), Positives = 99/239 (41%), Gaps = 7/239 (2%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I CL + L A+G ++W + TL GH I ++F+ + +++GS
Sbjct: 180 IVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSF 239
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D TVVVW GH + I + D ++ + +W +G + +
Sbjct: 240 DHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATL 299
Query: 1089 TGPSASI-DVTLNM--KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
TG I D + K + D + RI+S A + + H I+ +
Sbjct: 300 TGHDDEILDSCFDYTGKLIATASADGTARIFSAA---TRKCIAKLEGHEGEISKISFNPQ 356
Query: 1146 SQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
H++TGS D + ++W G+ QVL GH+D + A + V++GS D +W
Sbjct: 357 GNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNI-VITGSKDNTCRIW 414
Score = 80.2 bits (189), Expect = 5e-14
Identities = 49/213 (23%), Positives = 98/213 (46%), Gaps = 8/213 (3%)
Query: 997 THRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTL 1056
T L L HI +T V + + ++GS DRT +W A T +GH + + +
Sbjct: 81 TFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAI 140
Query: 1057 LMMSD-GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDG--DNS 1112
+ G + + + +W V++G H+ G +A I ++ N + +++ G D +
Sbjct: 141 AFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTT 200
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
++W + G+ R H+ I + ++TGS D ++ VW D G+ +L
Sbjct: 201 AKLWDIQNGEEVYTLR---GHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNIL 257
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+GH ++ + + + + +++GS D +WD
Sbjct: 258 IGHCAEISSASFN-WDCSLILTGSMDKTCKLWD 289
Score = 72.9 bits (171), Expect = 8e-12
Identities = 75/331 (22%), Positives = 134/331 (40%), Gaps = 31/331 (9%)
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVF 833
L H +T+V + + G+ FITGS D T W+ + L+T+ + ++ + +N +
Sbjct: 88 LKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNV-VYAIAFNNPY 146
Query: 834 ---LLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCAD-------- 882
+ T D L + TG H + H A++ C S+ VA G D
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI 206
Query: 883 ---QRIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLL--AAGGNRVTIYSFH-TEDNL 936
+ +Y HSA+++ ++ A G +V I H E +
Sbjct: 207 QNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISS 266
Query: 937 TNFR------PTKQM-KRRQTKSTTN---ITLLQAEQSDLIPISCLEVSRDGQLGASGCA 986
+F T M K + TN + L +++ SC + + G+L A+ A
Sbjct: 267 ASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILD-SCFDYT--GKLIATASA 323
Query: 987 RGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTY 1046
G R++ +T + A L GH G I+ ++F+P +L+GS D+T +W
Sbjct: 324 DGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVL 383
Query: 1047 KGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
+GH+ I + G ++ + +W
Sbjct: 384 EGHTDEIFSCAFNYKGNIVITGSKDNTCRIW 414
Score = 61.7 bits (143), Expect = 2e-08
Identities = 47/215 (21%), Positives = 84/215 (39%), Gaps = 2/215 (0%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRE-SQYLLTGSEDTSVIVWDLHTLAVKTKILEH 735
+LW S +++T +GH + + + TGS D + +W + T H
Sbjct: 117 KLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGH 176
Query: 736 IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFIT 795
A ++C++ +LV +G D+ + + +G V L H + S+ G+ IT
Sbjct: 177 TAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIIT 236
Query: 796 GSQDGTVCTWNVENFTLLSTVTAG-VPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYL 854
GS D TV W+ + ++ + I D +LT D L G +
Sbjct: 237 GSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCV 296
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
L H ++ C + +A AD ++S
Sbjct: 297 ATLTGHDDEILDSCFDYTGKLIATASADGTARIFS 331
Score = 58.8 bits (136), Expect = 1e-07
Identities = 35/161 (21%), Positives = 66/161 (40%), Gaps = 7/161 (4%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQ 1191
+H +T AL +TGS D + K+W G+ L GH ++V +A + +
Sbjct: 90 AHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDK 149
Query: 1192 VVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ +GS+D +W + T ++ C+ T+ + + D T +W+ + G
Sbjct: 150 IATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNG 209
Query: 1252 ---LALTSFSLHVPLLGFQITSDCARVVVHLLDRGCLPIIW 1289
L S + L F + D R++ D ++W
Sbjct: 210 EEVYTLRGHSAEIISLSFNTSGD--RIITGSFDH--TVVVW 246
Score = 55.2 bits (127), Expect = 2e-06
Identities = 34/151 (22%), Positives = 55/151 (36%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L SG ++ +W + KV+ GH I + +LTGS D +
Sbjct: 225 LSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKT 284
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+WD + H +L L+ + D I S + KL+ H
Sbjct: 285 CKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGH 344
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
G ++ + GN +TGS D T W+ +
Sbjct: 345 EGEISKISFNPQGNHLLTGSSDKTARIWDAQ 375
Score = 53.6 bits (123), Expect = 5e-06
Identities = 43/197 (21%), Positives = 74/197 (37%), Gaps = 6/197 (3%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I L + G +G V VW T R L GH I+ +F+ + L+L+GS
Sbjct: 222 IISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSM 281
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D+T +W + T GH I G+ ++ ++ + +
Sbjct: 282 DKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKL 341
Query: 1089 TGPSASID-VTLNMK--YAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
G I ++ N + + + D + RIW G + H + I A
Sbjct: 342 EGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLE---GHTDEIFSCAFNYK 398
Query: 1146 SQHVVTGSMDMSLKVWK 1162
V+TGS D + ++W+
Sbjct: 399 GNIVITGSKDNTCRIWR 415
Score = 51.2 bits (117), Expect = 3e-05
Identities = 32/129 (24%), Positives = 51/129 (39%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
+LW + V T GH IL C + + T S D + ++ T K+ H
Sbjct: 286 KLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHE 345
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
+ ++ + +++G D I G + L+ H + S GNI ITG
Sbjct: 346 GEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITG 405
Query: 797 SQDGTVCTW 805
S+D T W
Sbjct: 406 SKDNTCRIW 414
Score = 46.8 bits (106), Expect = 6e-04
Identities = 67/351 (19%), Positives = 127/351 (36%), Gaps = 29/351 (8%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVN--R 748
K H + + + + +TGS D + +WD + + LE V+ A N
Sbjct: 89 KAHILPLTNVALNKSGSCFITGSYDRTCKLWDTAS-GEELNTLEGHRNVVYAIAFNNPYG 147
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
+ +G D + S+ G H + + + TGS D T W+++
Sbjct: 148 DKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQ 207
Query: 809 NFTLLSTV---TAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVK 865
N + T+ +A + F+ + D + +T D+ + + TG ++ L H A++
Sbjct: 208 NGEEVYTLRGHSAEIISLSFNTSGDRI--ITGSFDHTVVVWDADTGRKVNILIGHCAEIS 265
Query: 866 CFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRV 925
D S + G D+ L+ + + + T L+A
Sbjct: 266 SASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADG 325
Query: 926 TIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGC 985
T F T++ I L+ + + IS + + G +G
Sbjct: 326 TARIFSA--------ATRKC----------IAKLEGHEGE---ISKISFNPQGNHLLTGS 364
Query: 986 ARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQ 1036
+ R+W T + L GH I F+ +V++GS+D T +W+
Sbjct: 365 SDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIWR 415
Score = 41.5 bits (93), Expect = 0.021
Identities = 22/96 (22%), Positives = 43/96 (44%)
Query: 663 SGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWD 722
+G+ + A + G +++ + + +GH G I + + +LLTGS D + +WD
Sbjct: 314 TGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWD 373
Query: 723 LHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDS 758
T + H + A ++VI+G D+
Sbjct: 374 AQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDN 409
Score = 37.5 bits (83), Expect = 0.35
Identities = 14/60 (23%), Positives = 27/60 (45%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVW 721
P G HL+ S ++W + + +GH+ I + ++TGS+D + +W
Sbjct: 355 PQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIW 414
>AK097409-1|BAC05039.1| 415|Homo sapiens protein ( Homo sapiens cDNA
FLJ40090 fis, clone TESTI2003596, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 415
Score = 90.6 bits (215), Expect = 4e-17
Identities = 63/270 (23%), Positives = 116/270 (42%), Gaps = 11/270 (4%)
Query: 982 ASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNS 1041
A+G ++W + T + T GH I C++F+P + LV +GS D T +W + +
Sbjct: 151 ATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGE 210
Query: 1042 PSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLN 1100
T +GHS+ I +L + G R ++ V VW D+G ++ G A I + N
Sbjct: 211 EVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFN 270
Query: 1101 MKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERI--TCFALTADSQHVVTGSMDM 1156
+++ G D + ++W N + H + I +CF T + + T S D
Sbjct: 271 WDCSLILTGSMDKTCKLWD---ATNGKCVATLTGHDDEILDSCFDYT--GKLIATASADG 325
Query: 1157 SLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXX 1216
+ +++ K L GH ++ ++ + +++GS D +WD T
Sbjct: 326 TARIFSAATRKCIAKLEGHEGEISKISFN-PQGNHLLTGSSDKTARIWDAQTGQCLQVLE 384
Query: 1217 XXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
++ G I ++ ++D T IW
Sbjct: 385 GHTDEIFSCAFNYKGNIVITGSKDNTCRIW 414
Score = 89.0 bits (211), Expect = 1e-16
Identities = 63/307 (20%), Positives = 125/307 (40%), Gaps = 8/307 (2%)
Query: 958 LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTF- 1016
L + ++ ++P++ + +++ G +G ++W ++ TL GH + + F
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFN 143
Query: 1017 SPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHV 1076
+P + +GS D+T +W + T++GH++ I L + +
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKL 203
Query: 1077 WLVDSGIVLHSATGPSAS-IDVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSH 1133
W + +G +++ G SA I ++ N + G D++V +W D + H
Sbjct: 204 WDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWD---ADTGRKVNILIGH 260
Query: 1134 AERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVV 1193
I+ + D ++TGSMD + K+W GK L GH D + T K +
Sbjct: 261 CAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKL-IA 319
Query: 1194 SGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLA 1253
+ S D ++ T +++ + G ++ + DKT IW+ + G
Sbjct: 320 TASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQC 379
Query: 1254 LTSFSLH 1260
L H
Sbjct: 380 LQVLEGH 386
Score = 84.2 bits (199), Expect = 3e-15
Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 3/223 (1%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
+LW + + HTF+GH+ I+C+ +S + TGS DT+ +WD+ + H
Sbjct: 160 KLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHS 219
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A ++ ++ + +I+G D V++ G V L H ++S D ++ +TG
Sbjct: 220 AEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTG 279
Query: 797 SQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDD--NVFLLTLQGDNELHLRTFITGTYL 854
S D T W+ N ++T+T G I D D + T D + + T +
Sbjct: 280 SMDKTCKLWDATNGKCVATLT-GHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCI 338
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
L+ H+ ++ + + G +D+ ++ + Q L+
Sbjct: 339 AKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQ 381
Score = 80.6 bits (190), Expect = 4e-14
Identities = 58/239 (24%), Positives = 99/239 (41%), Gaps = 7/239 (2%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I CL + L A+G ++W + TL GH I ++F+ + +++GS
Sbjct: 180 IVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSF 239
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D TVVVW GH + I + D ++ + +W +G + +
Sbjct: 240 DHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATL 299
Query: 1089 TGPSASI-DVTLNM--KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
TG I D + K + D + RI+S A + + H I+ +
Sbjct: 300 TGHDDEILDSCFDYTGKLIATASADGTARIFSAA---TRKCIAKLEGHEGEISKISFNPQ 356
Query: 1146 SQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
H++TGS D + ++W G+ QVL GH+D + A + V++GS D +W
Sbjct: 357 GNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNI-VITGSKDNTCRIW 414
Score = 80.2 bits (189), Expect = 5e-14
Identities = 49/213 (23%), Positives = 98/213 (46%), Gaps = 8/213 (3%)
Query: 997 THRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTL 1056
T L L HI +T V + + ++GS DRT +W A T +GH + + +
Sbjct: 81 TFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAI 140
Query: 1057 LMMSD-GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDG--DNS 1112
+ G + + + +W V++G H+ G +A I ++ N + +++ G D +
Sbjct: 141 AFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTT 200
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
++W + G+ R H+ I + ++TGS D ++ VW D G+ +L
Sbjct: 201 AKLWDIQNGEEVYTLR---GHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNIL 257
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+GH ++ + + + + +++GS D +WD
Sbjct: 258 IGHCAEISSASFN-WDCSLILTGSMDKTCKLWD 289
Score = 72.9 bits (171), Expect = 8e-12
Identities = 75/331 (22%), Positives = 134/331 (40%), Gaps = 31/331 (9%)
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVF 833
L H +T+V + + G+ FITGS D T W+ + L+T+ + ++ + +N +
Sbjct: 88 LKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNV-VYAIAFNNPY 146
Query: 834 ---LLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCAD-------- 882
+ T D L + TG H + H A++ C S+ VA G D
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI 206
Query: 883 ---QRIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLL--AAGGNRVTIYSFH-TEDNL 936
+ +Y HSA+++ ++ A G +V I H E +
Sbjct: 207 QNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISS 266
Query: 937 TNFR------PTKQM-KRRQTKSTTN---ITLLQAEQSDLIPISCLEVSRDGQLGASGCA 986
+F T M K + TN + L +++ SC + + G+L A+ A
Sbjct: 267 ASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILD-SCFDYT--GKLIATASA 323
Query: 987 RGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTY 1046
G R++ +T + A L GH G I+ ++F+P +L+GS D+T +W
Sbjct: 324 DGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVL 383
Query: 1047 KGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
+GH+ I + G ++ + +W
Sbjct: 384 EGHTDEIFSCAFNYKGNIVITGSKDNTCRIW 414
Score = 61.7 bits (143), Expect = 2e-08
Identities = 47/215 (21%), Positives = 84/215 (39%), Gaps = 2/215 (0%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRE-SQYLLTGSEDTSVIVWDLHTLAVKTKILEH 735
+LW S +++T +GH + + + TGS D + +W + T H
Sbjct: 117 KLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGH 176
Query: 736 IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFIT 795
A ++C++ +LV +G D+ + + +G V L H + S+ G+ IT
Sbjct: 177 TAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIIT 236
Query: 796 GSQDGTVCTWNVENFTLLSTVTAG-VPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYL 854
GS D TV W+ + ++ + I D +LT D L G +
Sbjct: 237 GSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCV 296
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
L H ++ C + +A AD ++S
Sbjct: 297 ATLTGHDDEILDSCFDYTGKLIATASADGTARIFS 331
Score = 58.8 bits (136), Expect = 1e-07
Identities = 35/161 (21%), Positives = 66/161 (40%), Gaps = 7/161 (4%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQ 1191
+H +T AL +TGS D + K+W G+ L GH ++V +A + +
Sbjct: 90 AHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDK 149
Query: 1192 VVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ +GS+D +W + T ++ C+ T+ + + D T +W+ + G
Sbjct: 150 IATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNG 209
Query: 1252 ---LALTSFSLHVPLLGFQITSDCARVVVHLLDRGCLPIIW 1289
L S + L F + D R++ D ++W
Sbjct: 210 EEVYTLRGHSAEIISLSFNTSGD--RIITGSFDH--TVVVW 246
Score = 55.2 bits (127), Expect = 2e-06
Identities = 34/151 (22%), Positives = 55/151 (36%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L SG ++ +W + KV+ GH I + +LTGS D +
Sbjct: 225 LSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKT 284
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+WD + H +L L+ + D I S + KL+ H
Sbjct: 285 CKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGH 344
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
G ++ + GN +TGS D T W+ +
Sbjct: 345 EGEISKISFNPQGNHLLTGSSDKTARIWDAQ 375
Score = 53.6 bits (123), Expect = 5e-06
Identities = 43/197 (21%), Positives = 74/197 (37%), Gaps = 6/197 (3%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I L + G +G V VW T R L GH I+ +F+ + L+L+GS
Sbjct: 222 IISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSM 281
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D+T +W + T GH I G+ ++ ++ + +
Sbjct: 282 DKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKL 341
Query: 1089 TGPSASID-VTLNMK--YAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
G I ++ N + + + D + RIW G + H + I A
Sbjct: 342 EGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLE---GHTDEIFSCAFNYK 398
Query: 1146 SQHVVTGSMDMSLKVWK 1162
V+TGS D + ++W+
Sbjct: 399 GNIVITGSKDNTCRIWR 415
Score = 51.2 bits (117), Expect = 3e-05
Identities = 32/129 (24%), Positives = 51/129 (39%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
+LW + V T GH IL C + + T S D + ++ T K+ H
Sbjct: 286 KLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHE 345
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
+ ++ + +++G D I G + L+ H + S GNI ITG
Sbjct: 346 GEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITG 405
Query: 797 SQDGTVCTW 805
S+D T W
Sbjct: 406 SKDNTCRIW 414
Score = 46.8 bits (106), Expect = 6e-04
Identities = 67/351 (19%), Positives = 127/351 (36%), Gaps = 29/351 (8%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVN--R 748
K H + + + + +TGS D + +WD + + LE V+ A N
Sbjct: 89 KAHILPLTNVALNKSGSCFITGSYDRTCKLWDTAS-GEELNTLEGHRNVVYAIAFNNPYG 147
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
+ +G D + S+ G H + + + TGS D T W+++
Sbjct: 148 DKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQ 207
Query: 809 NFTLLSTV---TAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVK 865
N + T+ +A + F+ + D + +T D+ + + TG ++ L H A++
Sbjct: 208 NGEEVYTLRGHSAEIISLSFNTSGDRI--ITGSFDHTVVVWDADTGRKVNILIGHCAEIS 265
Query: 866 CFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRV 925
D S + G D+ L+ + + + T L+A
Sbjct: 266 SASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADG 325
Query: 926 TIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGC 985
T F T++ I L+ + + IS + + G +G
Sbjct: 326 TARIFSA--------ATRKC----------IAKLEGHEGE---ISKISFNPQGNHLLTGS 364
Query: 986 ARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQ 1036
+ R+W T + L GH I F+ +V++GS+D T +W+
Sbjct: 365 SDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIWR 415
Score = 41.5 bits (93), Expect = 0.021
Identities = 22/96 (22%), Positives = 43/96 (44%)
Query: 663 SGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWD 722
+G+ + A + G +++ + + +GH G I + + +LLTGS D + +WD
Sbjct: 314 TGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWD 373
Query: 723 LHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDS 758
T + H + A ++VI+G D+
Sbjct: 374 AQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDN 409
Score = 37.5 bits (83), Expect = 0.35
Identities = 14/60 (23%), Positives = 27/60 (45%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVW 721
P G HL+ S ++W + + +GH+ I + ++TGS+D + +W
Sbjct: 355 PQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIW 414
>AC073065-2|AAX93215.1| 415|Homo sapiens unknown protein.
Length = 415
Score = 90.6 bits (215), Expect = 4e-17
Identities = 63/270 (23%), Positives = 116/270 (42%), Gaps = 11/270 (4%)
Query: 982 ASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNS 1041
A+G ++W + T + T GH I C++F+P + LV +GS D T +W + +
Sbjct: 151 ATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGE 210
Query: 1042 PSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLN 1100
T +GHS+ I +L + G R ++ V VW D+G ++ G A I + N
Sbjct: 211 EVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFN 270
Query: 1101 MKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERI--TCFALTADSQHVVTGSMDM 1156
+++ G D + ++W N + H + I +CF T + + T S D
Sbjct: 271 WDCSLILTGSMDKTCKLWD---ATNGKCVATLTGHDDEILDSCFDYT--GKLIATASADG 325
Query: 1157 SLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXX 1216
+ +++ K L GH ++ ++ + +++GS D +WD T
Sbjct: 326 TARIFSAATRKCIAKLEGHEGEISKISFN-PQGNHLLTGSSDKTARIWDAQTGQCLQVLE 384
Query: 1217 XXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
++ G I ++ ++D T IW
Sbjct: 385 GHTDEIFSCAFNYKGNIVITGSKDNTCRIW 414
Score = 89.0 bits (211), Expect = 1e-16
Identities = 63/307 (20%), Positives = 125/307 (40%), Gaps = 8/307 (2%)
Query: 958 LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTF- 1016
L + ++ ++P++ + +++ G +G ++W ++ TL GH + + F
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFN 143
Query: 1017 SPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHV 1076
+P + +GS D+T +W + T++GH++ I L + +
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKL 203
Query: 1077 WLVDSGIVLHSATGPSAS-IDVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSH 1133
W + +G +++ G SA I ++ N + G D++V +W D + H
Sbjct: 204 WDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWD---ADTGRKVNILIGH 260
Query: 1134 AERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVV 1193
I+ + D ++TGSMD + K+W GK L GH D + T K +
Sbjct: 261 CAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKL-IA 319
Query: 1194 SGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLA 1253
+ S D ++ T +++ + G ++ + DKT IW+ + G
Sbjct: 320 TASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQC 379
Query: 1254 LTSFSLH 1260
L H
Sbjct: 380 LQVLEGH 386
Score = 84.2 bits (199), Expect = 3e-15
Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 3/223 (1%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
+LW + + HTF+GH+ I+C+ +S + TGS DT+ +WD+ + H
Sbjct: 160 KLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHS 219
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A ++ ++ + +I+G D V++ G V L H ++S D ++ +TG
Sbjct: 220 AEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTG 279
Query: 797 SQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDD--NVFLLTLQGDNELHLRTFITGTYL 854
S D T W+ N ++T+T G I D D + T D + + T +
Sbjct: 280 SMDKTCKLWDATNGKCVATLT-GHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCI 338
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
L+ H+ ++ + + G +D+ ++ + Q L+
Sbjct: 339 AKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQ 381
Score = 80.6 bits (190), Expect = 4e-14
Identities = 58/239 (24%), Positives = 99/239 (41%), Gaps = 7/239 (2%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I CL + L A+G ++W + TL GH I ++F+ + +++GS
Sbjct: 180 IVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSF 239
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D TVVVW GH + I + D ++ + +W +G + +
Sbjct: 240 DHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATL 299
Query: 1089 TGPSASI-DVTLNM--KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
TG I D + K + D + RI+S A + + H I+ +
Sbjct: 300 TGHDDEILDSCFDYTGKLIATASADGTARIFSAA---TRKCIAKLEGHEGEISKISFNPQ 356
Query: 1146 SQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
H++TGS D + ++W G+ QVL GH+D + A + V++GS D +W
Sbjct: 357 GNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNI-VITGSKDNTCRIW 414
Score = 80.2 bits (189), Expect = 5e-14
Identities = 49/213 (23%), Positives = 98/213 (46%), Gaps = 8/213 (3%)
Query: 997 THRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTL 1056
T L L HI +T V + + ++GS DRT +W A T +GH + + +
Sbjct: 81 TFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAI 140
Query: 1057 LMMSD-GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDG--DNS 1112
+ G + + + +W V++G H+ G +A I ++ N + +++ G D +
Sbjct: 141 AFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTT 200
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
++W + G+ R H+ I + ++TGS D ++ VW D G+ +L
Sbjct: 201 AKLWDIQNGEEVYTLR---GHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNIL 257
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+GH ++ + + + + +++GS D +WD
Sbjct: 258 IGHCAEISSASFN-WDCSLILTGSMDKTCKLWD 289
Score = 72.9 bits (171), Expect = 8e-12
Identities = 75/331 (22%), Positives = 134/331 (40%), Gaps = 31/331 (9%)
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVF 833
L H +T+V + + G+ FITGS D T W+ + L+T+ + ++ + +N +
Sbjct: 88 LKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNV-VYAIAFNNPY 146
Query: 834 ---LLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCAD-------- 882
+ T D L + TG H + H A++ C S+ VA G D
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI 206
Query: 883 ---QRIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLL--AAGGNRVTIYSFH-TEDNL 936
+ +Y HSA+++ ++ A G +V I H E +
Sbjct: 207 QNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISS 266
Query: 937 TNFR------PTKQM-KRRQTKSTTN---ITLLQAEQSDLIPISCLEVSRDGQLGASGCA 986
+F T M K + TN + L +++ SC + + G+L A+ A
Sbjct: 267 ASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILD-SCFDYT--GKLIATASA 323
Query: 987 RGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTY 1046
G R++ +T + A L GH G I+ ++F+P +L+GS D+T +W
Sbjct: 324 DGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVL 383
Query: 1047 KGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
+GH+ I + G ++ + +W
Sbjct: 384 EGHTDEIFSCAFNYKGNIVITGSKDNTCRIW 414
Score = 61.7 bits (143), Expect = 2e-08
Identities = 47/215 (21%), Positives = 84/215 (39%), Gaps = 2/215 (0%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRE-SQYLLTGSEDTSVIVWDLHTLAVKTKILEH 735
+LW S +++T +GH + + + TGS D + +W + T H
Sbjct: 117 KLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGH 176
Query: 736 IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFIT 795
A ++C++ +LV +G D+ + + +G V L H + S+ G+ IT
Sbjct: 177 TAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIIT 236
Query: 796 GSQDGTVCTWNVENFTLLSTVTAG-VPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYL 854
GS D TV W+ + ++ + I D +LT D L G +
Sbjct: 237 GSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCV 296
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
L H ++ C + +A AD ++S
Sbjct: 297 ATLTGHDDEILDSCFDYTGKLIATASADGTARIFS 331
Score = 58.8 bits (136), Expect = 1e-07
Identities = 35/161 (21%), Positives = 66/161 (40%), Gaps = 7/161 (4%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQ 1191
+H +T AL +TGS D + K+W G+ L GH ++V +A + +
Sbjct: 90 AHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDK 149
Query: 1192 VVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ +GS+D +W + T ++ C+ T+ + + D T +W+ + G
Sbjct: 150 IATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNG 209
Query: 1252 ---LALTSFSLHVPLLGFQITSDCARVVVHLLDRGCLPIIW 1289
L S + L F + D R++ D ++W
Sbjct: 210 EEVYTLRGHSAEIISLSFNTSGD--RIITGSFDH--TVVVW 246
Score = 55.2 bits (127), Expect = 2e-06
Identities = 34/151 (22%), Positives = 55/151 (36%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L SG ++ +W + KV+ GH I + +LTGS D +
Sbjct: 225 LSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKT 284
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+WD + H +L L+ + D I S + KL+ H
Sbjct: 285 CKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGH 344
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
G ++ + GN +TGS D T W+ +
Sbjct: 345 EGEISKISFNPQGNHLLTGSSDKTARIWDAQ 375
Score = 53.6 bits (123), Expect = 5e-06
Identities = 43/197 (21%), Positives = 74/197 (37%), Gaps = 6/197 (3%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I L + G +G V VW T R L GH I+ +F+ + L+L+GS
Sbjct: 222 IISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSM 281
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D+T +W + T GH I G+ ++ ++ + +
Sbjct: 282 DKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKL 341
Query: 1089 TGPSASID-VTLNMK--YAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
G I ++ N + + + D + RIW G + H + I A
Sbjct: 342 EGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLE---GHTDEIFSCAFNYK 398
Query: 1146 SQHVVTGSMDMSLKVWK 1162
V+TGS D + ++W+
Sbjct: 399 GNIVITGSKDNTCRIWR 415
Score = 51.2 bits (117), Expect = 3e-05
Identities = 32/129 (24%), Positives = 51/129 (39%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
+LW + V T GH IL C + + T S D + ++ T K+ H
Sbjct: 286 KLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHE 345
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
+ ++ + +++G D I G + L+ H + S GNI ITG
Sbjct: 346 GEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITG 405
Query: 797 SQDGTVCTW 805
S+D T W
Sbjct: 406 SKDNTCRIW 414
Score = 46.8 bits (106), Expect = 6e-04
Identities = 67/351 (19%), Positives = 127/351 (36%), Gaps = 29/351 (8%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVN--R 748
K H + + + + +TGS D + +WD + + LE V+ A N
Sbjct: 89 KAHILPLTNVALNKSGSCFITGSYDRTCKLWDTAS-GEELNTLEGHRNVVYAIAFNNPYG 147
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
+ +G D + S+ G H + + + TGS D T W+++
Sbjct: 148 DKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQ 207
Query: 809 NFTLLSTV---TAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVK 865
N + T+ +A + F+ + D + +T D+ + + TG ++ L H A++
Sbjct: 208 NGEEVYTLRGHSAEIISLSFNTSGDRI--ITGSFDHTVVVWDADTGRKVNILIGHCAEIS 265
Query: 866 CFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRV 925
D S + G D+ L+ + + + T L+A
Sbjct: 266 SASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADG 325
Query: 926 TIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGC 985
T F T++ I L+ + + IS + + G +G
Sbjct: 326 TARIFSA--------ATRKC----------IAKLEGHEGE---ISKISFNPQGNHLLTGS 364
Query: 986 ARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQ 1036
+ R+W T + L GH I F+ +V++GS+D T +W+
Sbjct: 365 SDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIWR 415
Score = 41.5 bits (93), Expect = 0.021
Identities = 22/96 (22%), Positives = 43/96 (44%)
Query: 663 SGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWD 722
+G+ + A + G +++ + + +GH G I + + +LLTGS D + +WD
Sbjct: 314 TGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWD 373
Query: 723 LHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDS 758
T + H + A ++VI+G D+
Sbjct: 374 AQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDN 409
Score = 37.5 bits (83), Expect = 0.35
Identities = 14/60 (23%), Positives = 27/60 (45%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVW 721
P G HL+ S ++W + + +GH+ I + ++TGS+D + +W
Sbjct: 355 PQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIW 414
>CR457105-1|CAG33386.1| 521|Homo sapiens PRPF4 protein.
Length = 521
Score = 90.2 bits (214), Expect = 5e-17
Identities = 71/316 (22%), Positives = 131/316 (41%), Gaps = 15/316 (4%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T QM+ KS ++ ++ D PIS S + ++ A+ C GL ++W + L
Sbjct: 207 TSQMQELH-KSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLL 265
Query: 1002 ATLNGHIGHITCVTFSPNNLLVL--------SGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
TL GH ++ + F P + + L S + D +V +W L + P +GH+ +
Sbjct: 266 HTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRV 325
Query: 1054 QTLLMMSDGRRAMSSDRARNVHVW-LVDSGIVLHSATGPSASIDVTLNMKYAVLSDG--D 1110
++ GR ++ R+ +W L +LH D+ + ++ G D
Sbjct: 326 ARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLD 385
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
R+W L G H + I + + H+ TGS D + KVW L +
Sbjct: 386 AFGRVWDLRTG---RCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 442
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
+ H ++VT V + +++G++D +W KV + ++ D
Sbjct: 443 TIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSD 502
Query: 1231 GTIAVSCAEDKTLIIW 1246
G + +C+ D+T +W
Sbjct: 503 GQLIATCSYDRTFKLW 518
Score = 57.2 bits (132), Expect = 4e-07
Identities = 56/234 (23%), Positives = 93/234 (39%), Gaps = 4/234 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ L P +L + G +LW + S+ V +GH+ + + ++L T D S
Sbjct: 286 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRS 345
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+WDL H V +A + SL +GG D+ + L G + L+ H
Sbjct: 346 WRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGH 405
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHI---FDVTDDNVFL 834
+ + +G TGS D T W++ + T+ A + F+ N FL
Sbjct: 406 LKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGN-FL 464
Query: 835 LTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
LT DN + T + L L H+ KV ++ D +A D+ L+
Sbjct: 465 LTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
Score = 53.2 bits (122), Expect = 7e-06
Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSP-NNLLVLSGSEDR 1030
+ S +G A+G +VW L R T+ H +T V F P + +L+G+ D
Sbjct: 412 INFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDN 471
Query: 1031 TVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
T +W SP T GH + L + SDG+ + R +W+ D
Sbjct: 472 TAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAD 521
Score = 36.7 bits (81), Expect = 0.61
Identities = 32/178 (17%), Positives = 63/178 (35%), Gaps = 7/178 (3%)
Query: 991 RVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
R+W L GH + + F + L +G D VW L + +GH
Sbjct: 347 RLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHL 406
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVT----LNMKYAVL 1106
I + +G + VW + +++ + ++ + +
Sbjct: 407 KEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLT 466
Query: 1107 SDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLD 1164
DN+ +IW+ G + H ++ +++D Q + T S D + K+W D
Sbjct: 467 GAYDNTAKIWTHPGWSPL---KTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAD 521
Score = 35.1 bits (77), Expect = 1.9
Identities = 32/155 (20%), Positives = 61/155 (39%), Gaps = 4/155 (2%)
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLS 1169
D SV++WSL D+ E H R+ + + T D S ++W L+ +
Sbjct: 301 DGSVKLWSL---DSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEI 357
Query: 1170 QVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTG 1229
GHS V +A + + +G D VWD+ T ++ + +
Sbjct: 358 LHQEGHSMGVYDIAFH-QDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSP 416
Query: 1230 DGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+G + + D T +W+ ++ + + H L+
Sbjct: 417 NGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLV 451
>BC007424-1|AAH07424.1| 521|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 521
Score = 90.2 bits (214), Expect = 5e-17
Identities = 71/316 (22%), Positives = 131/316 (41%), Gaps = 15/316 (4%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T QM+ KS ++ ++ D PIS S + ++ A+ C GL ++W + L
Sbjct: 207 TSQMQELH-KSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLL 265
Query: 1002 ATLNGHIGHITCVTFSPNNLLVL--------SGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
TL GH ++ + F P + + L S + D +V +W L + P +GH+ +
Sbjct: 266 HTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRV 325
Query: 1054 QTLLMMSDGRRAMSSDRARNVHVW-LVDSGIVLHSATGPSASIDVTLNMKYAVLSDG--D 1110
++ GR ++ R+ +W L +LH D+ + ++ G D
Sbjct: 326 ARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLD 385
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
R+W L G H + I + + H+ TGS D + KVW L +
Sbjct: 386 AFGRVWDLRTG---RCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 442
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
+ H ++VT V + +++G++D +W KV + ++ D
Sbjct: 443 TIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSD 502
Query: 1231 GTIAVSCAEDKTLIIW 1246
G + +C+ D+T +W
Sbjct: 503 GQLIATCSYDRTFKLW 518
Score = 57.2 bits (132), Expect = 4e-07
Identities = 56/234 (23%), Positives = 93/234 (39%), Gaps = 4/234 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ L P +L + G +LW + S+ V +GH+ + + ++L T D S
Sbjct: 286 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRS 345
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+WDL H V +A + SL +GG D+ + L G + L+ H
Sbjct: 346 WRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGH 405
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHI---FDVTDDNVFL 834
+ + +G TGS D T W++ + T+ A + F+ N FL
Sbjct: 406 LKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGN-FL 464
Query: 835 LTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
LT DN + T + L L H+ KV ++ D +A D+ L+
Sbjct: 465 LTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSP-NNLLVLSGSEDR 1030
+ S +G A+G +VW L R T+ H +T V F P + +L+G+ D
Sbjct: 412 INFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDN 471
Query: 1031 TVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
T +W SP T GH + L + SDG+ + R +W+ +
Sbjct: 472 TAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE 521
Score = 43.2 bits (97), Expect = 0.007
Identities = 31/133 (23%), Positives = 55/133 (41%), Gaps = 1/133 (0%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + + + +GH I + + ++ TGS D + VWDL I H
Sbjct: 389 RVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQ 448
Query: 737 APVLCVA-AIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFIT 795
V V ++ + +++G D+ I + + + L H G V + + DG + T
Sbjct: 449 NLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIAT 508
Query: 796 GSQDGTVCTWNVE 808
S D T W E
Sbjct: 509 CSYDRTFKLWMAE 521
Score = 35.1 bits (77), Expect = 1.9
Identities = 32/155 (20%), Positives = 61/155 (39%), Gaps = 4/155 (2%)
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLS 1169
D SV++WSL D+ E H R+ + + T D S ++W L+ +
Sbjct: 301 DGSVKLWSL---DSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEI 357
Query: 1170 QVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTG 1229
GHS V +A + + +G D VWD+ T ++ + +
Sbjct: 358 LHQEGHSMGVYDIAFH-QDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSP 416
Query: 1230 DGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+G + + D T +W+ ++ + + H L+
Sbjct: 417 NGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLV 451
>BC001588-1|AAH01588.1| 522|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 522
Score = 90.2 bits (214), Expect = 5e-17
Identities = 71/316 (22%), Positives = 131/316 (41%), Gaps = 15/316 (4%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T QM+ KS ++ ++ D PIS S + ++ A+ C GL ++W + L
Sbjct: 208 TSQMQELH-KSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLL 266
Query: 1002 ATLNGHIGHITCVTFSPNNLLVL--------SGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
TL GH ++ + F P + + L S + D +V +W L + P +GH+ +
Sbjct: 267 HTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRV 326
Query: 1054 QTLLMMSDGRRAMSSDRARNVHVW-LVDSGIVLHSATGPSASIDVTLNMKYAVLSDG--D 1110
++ GR ++ R+ +W L +LH D+ + ++ G D
Sbjct: 327 ARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLD 386
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
R+W L G H + I + + H+ TGS D + KVW L +
Sbjct: 387 AFGRVWDLRTG---RCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 443
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
+ H ++VT V + +++G++D +W KV + ++ D
Sbjct: 444 TIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSD 503
Query: 1231 GTIAVSCAEDKTLIIW 1246
G + +C+ D+T +W
Sbjct: 504 GQLIATCSYDRTFKLW 519
Score = 57.2 bits (132), Expect = 4e-07
Identities = 56/234 (23%), Positives = 93/234 (39%), Gaps = 4/234 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ L P +L + G +LW + S+ V +GH+ + + ++L T D S
Sbjct: 287 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRS 346
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+WDL H V +A + SL +GG D+ + L G + L+ H
Sbjct: 347 WRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGH 406
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHI---FDVTDDNVFL 834
+ + +G TGS D T W++ + T+ A + F+ N FL
Sbjct: 407 LKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGN-FL 465
Query: 835 LTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
LT DN + T + L L H+ KV ++ D +A D+ L+
Sbjct: 466 LTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSP-NNLLVLSGSEDR 1030
+ S +G A+G +VW L R T+ H +T V F P + +L+G+ D
Sbjct: 413 INFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDN 472
Query: 1031 TVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
T +W SP T GH + L + SDG+ + R +W+ +
Sbjct: 473 TAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE 522
Score = 43.2 bits (97), Expect = 0.007
Identities = 31/133 (23%), Positives = 55/133 (41%), Gaps = 1/133 (0%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + + + +GH I + + ++ TGS D + VWDL I H
Sbjct: 390 RVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQ 449
Query: 737 APVLCVA-AIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFIT 795
V V ++ + +++G D+ I + + + L H G V + + DG + T
Sbjct: 450 NLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIAT 509
Query: 796 GSQDGTVCTWNVE 808
S D T W E
Sbjct: 510 CSYDRTFKLWMAE 522
Score = 35.1 bits (77), Expect = 1.9
Identities = 32/155 (20%), Positives = 61/155 (39%), Gaps = 4/155 (2%)
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLS 1169
D SV++WSL D+ E H R+ + + T D S ++W L+ +
Sbjct: 302 DGSVKLWSL---DSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEI 358
Query: 1170 QVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTG 1229
GHS V +A + + +G D VWD+ T ++ + +
Sbjct: 359 LHQEGHSMGVYDIAFH-QDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSP 417
Query: 1230 DGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+G + + D T +W+ ++ + + H L+
Sbjct: 418 NGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLV 452
>AY572489-1|AAS78572.1| 521|Homo sapiens 60 kDa U4/U6 snRNP-specific
spliceosomal protein protein.
Length = 521
Score = 90.2 bits (214), Expect = 5e-17
Identities = 71/316 (22%), Positives = 131/316 (41%), Gaps = 15/316 (4%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T QM+ KS ++ ++ D PIS S + ++ A+ C GL ++W + L
Sbjct: 207 TSQMQELH-KSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLL 265
Query: 1002 ATLNGHIGHITCVTFSPNNLLVL--------SGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
TL GH ++ + F P + + L S + D +V +W L + P +GH+ +
Sbjct: 266 HTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRV 325
Query: 1054 QTLLMMSDGRRAMSSDRARNVHVW-LVDSGIVLHSATGPSASIDVTLNMKYAVLSDG--D 1110
++ GR ++ R+ +W L +LH D+ + ++ G D
Sbjct: 326 ARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLD 385
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
R+W L G H + I + + H+ TGS D + KVW L +
Sbjct: 386 AFGRVWDLRTG---RCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 442
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
+ H ++VT V + +++G++D +W KV + ++ D
Sbjct: 443 TIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSD 502
Query: 1231 GTIAVSCAEDKTLIIW 1246
G + +C+ D+T +W
Sbjct: 503 GQLIATCSYDRTFKLW 518
Score = 57.2 bits (132), Expect = 4e-07
Identities = 56/234 (23%), Positives = 93/234 (39%), Gaps = 4/234 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ L P +L + G +LW + S+ V +GH+ + + ++L T D S
Sbjct: 286 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRS 345
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+WDL H V +A + SL +GG D+ + L G + L+ H
Sbjct: 346 WRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGH 405
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHI---FDVTDDNVFL 834
+ + +G TGS D T W++ + T+ A + F+ N FL
Sbjct: 406 LKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGN-FL 464
Query: 835 LTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
LT DN + T + L L H+ KV ++ D +A D+ L+
Sbjct: 465 LTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSP-NNLLVLSGSEDR 1030
+ S +G A+G +VW L R T+ H +T V F P + +L+G+ D
Sbjct: 412 INFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDN 471
Query: 1031 TVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
T +W SP T GH + L + SDG+ + R +W+ +
Sbjct: 472 TAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE 521
Score = 43.2 bits (97), Expect = 0.007
Identities = 31/133 (23%), Positives = 55/133 (41%), Gaps = 1/133 (0%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + + + +GH I + + ++ TGS D + VWDL I H
Sbjct: 389 RVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQ 448
Query: 737 APVLCVA-AIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFIT 795
V V ++ + +++G D+ I + + + L H G V + + DG + T
Sbjct: 449 NLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIAT 508
Query: 796 GSQDGTVCTWNVE 808
S D T W E
Sbjct: 509 CSYDRTFKLWMAE 521
Score = 35.1 bits (77), Expect = 1.9
Identities = 32/155 (20%), Positives = 61/155 (39%), Gaps = 4/155 (2%)
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLS 1169
D SV++WSL D+ E H R+ + + T D S ++W L+ +
Sbjct: 301 DGSVKLWSL---DSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEI 357
Query: 1170 QVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTG 1229
GHS V +A + + +G D VWD+ T ++ + +
Sbjct: 358 LHQEGHSMGVYDIAFH-QDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSP 416
Query: 1230 DGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+G + + D T +W+ ++ + + H L+
Sbjct: 417 NGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLV 451
>AL449305-8|CAI10969.1| 521|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 521
Score = 90.2 bits (214), Expect = 5e-17
Identities = 71/316 (22%), Positives = 131/316 (41%), Gaps = 15/316 (4%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T QM+ KS ++ ++ D PIS S + ++ A+ C GL ++W + L
Sbjct: 207 TSQMQELH-KSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLL 265
Query: 1002 ATLNGHIGHITCVTFSPNNLLVL--------SGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
TL GH ++ + F P + + L S + D +V +W L + P +GH+ +
Sbjct: 266 HTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRV 325
Query: 1054 QTLLMMSDGRRAMSSDRARNVHVW-LVDSGIVLHSATGPSASIDVTLNMKYAVLSDG--D 1110
++ GR ++ R+ +W L +LH D+ + ++ G D
Sbjct: 326 ARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLD 385
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
R+W L G H + I + + H+ TGS D + KVW L +
Sbjct: 386 AFGRVWDLRTG---RCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 442
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
+ H ++VT V + +++G++D +W KV + ++ D
Sbjct: 443 TIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSD 502
Query: 1231 GTIAVSCAEDKTLIIW 1246
G + +C+ D+T +W
Sbjct: 503 GQLIATCSYDRTFKLW 518
Score = 57.2 bits (132), Expect = 4e-07
Identities = 56/234 (23%), Positives = 93/234 (39%), Gaps = 4/234 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ L P +L + G +LW + S+ V +GH+ + + ++L T D S
Sbjct: 286 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRS 345
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+WDL H V +A + SL +GG D+ + L G + L+ H
Sbjct: 346 WRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGH 405
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHI---FDVTDDNVFL 834
+ + +G TGS D T W++ + T+ A + F+ N FL
Sbjct: 406 LKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGN-FL 464
Query: 835 LTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
LT DN + T + L L H+ KV ++ D +A D+ L+
Sbjct: 465 LTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSP-NNLLVLSGSEDR 1030
+ S +G A+G +VW L R T+ H +T V F P + +L+G+ D
Sbjct: 412 INFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDN 471
Query: 1031 TVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
T +W SP T GH + L + SDG+ + R +W+ +
Sbjct: 472 TAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE 521
Score = 43.2 bits (97), Expect = 0.007
Identities = 31/133 (23%), Positives = 55/133 (41%), Gaps = 1/133 (0%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + + + +GH I + + ++ TGS D + VWDL I H
Sbjct: 389 RVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQ 448
Query: 737 APVLCVA-AIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFIT 795
V V ++ + +++G D+ I + + + L H G V + + DG + T
Sbjct: 449 NLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIAT 508
Query: 796 GSQDGTVCTWNVE 808
S D T W E
Sbjct: 509 CSYDRTFKLWMAE 521
Score = 35.1 bits (77), Expect = 1.9
Identities = 32/155 (20%), Positives = 61/155 (39%), Gaps = 4/155 (2%)
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLS 1169
D SV++WSL D+ E H R+ + + T D S ++W L+ +
Sbjct: 301 DGSVKLWSL---DSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEI 357
Query: 1170 QVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTG 1229
GHS V +A + + +G D VWD+ T ++ + +
Sbjct: 358 LHQEGHSMGVYDIAFH-QDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSP 416
Query: 1230 DGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+G + + D T +W+ ++ + + H L+
Sbjct: 417 NGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLV 451
>AL449305-7|CAI10968.1| 522|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 522
Score = 90.2 bits (214), Expect = 5e-17
Identities = 71/316 (22%), Positives = 131/316 (41%), Gaps = 15/316 (4%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T QM+ KS ++ ++ D PIS S + ++ A+ C GL ++W + L
Sbjct: 208 TSQMQELH-KSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLL 266
Query: 1002 ATLNGHIGHITCVTFSPNNLLVL--------SGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
TL GH ++ + F P + + L S + D +V +W L + P +GH+ +
Sbjct: 267 HTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRV 326
Query: 1054 QTLLMMSDGRRAMSSDRARNVHVW-LVDSGIVLHSATGPSASIDVTLNMKYAVLSDG--D 1110
++ GR ++ R+ +W L +LH D+ + ++ G D
Sbjct: 327 ARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLD 386
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
R+W L G H + I + + H+ TGS D + KVW L +
Sbjct: 387 AFGRVWDLRTG---RCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 443
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
+ H ++VT V + +++G++D +W KV + ++ D
Sbjct: 444 TIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSD 503
Query: 1231 GTIAVSCAEDKTLIIW 1246
G + +C+ D+T +W
Sbjct: 504 GQLIATCSYDRTFKLW 519
Score = 57.2 bits (132), Expect = 4e-07
Identities = 56/234 (23%), Positives = 93/234 (39%), Gaps = 4/234 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ L P +L + G +LW + S+ V +GH+ + + ++L T D S
Sbjct: 287 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRS 346
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+WDL H V +A + SL +GG D+ + L G + L+ H
Sbjct: 347 WRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGH 406
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHI---FDVTDDNVFL 834
+ + +G TGS D T W++ + T+ A + F+ N FL
Sbjct: 407 LKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGN-FL 465
Query: 835 LTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
LT DN + T + L L H+ KV ++ D +A D+ L+
Sbjct: 466 LTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSP-NNLLVLSGSEDR 1030
+ S +G A+G +VW L R T+ H +T V F P + +L+G+ D
Sbjct: 413 INFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDN 472
Query: 1031 TVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
T +W SP T GH + L + SDG+ + R +W+ +
Sbjct: 473 TAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE 522
Score = 43.2 bits (97), Expect = 0.007
Identities = 31/133 (23%), Positives = 55/133 (41%), Gaps = 1/133 (0%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + + + +GH I + + ++ TGS D + VWDL I H
Sbjct: 390 RVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQ 449
Query: 737 APVLCVA-AIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFIT 795
V V ++ + +++G D+ I + + + L H G V + + DG + T
Sbjct: 450 NLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIAT 509
Query: 796 GSQDGTVCTWNVE 808
S D T W E
Sbjct: 510 CSYDRTFKLWMAE 522
Score = 35.1 bits (77), Expect = 1.9
Identities = 32/155 (20%), Positives = 61/155 (39%), Gaps = 4/155 (2%)
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLS 1169
D SV++WSL D+ E H R+ + + T D S ++W L+ +
Sbjct: 302 DGSVKLWSL---DSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEI 358
Query: 1170 QVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTG 1229
GHS V +A + + +G D VWD+ T ++ + +
Sbjct: 359 LHQEGHSMGVYDIAFH-QDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSP 417
Query: 1230 DGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+G + + D T +W+ ++ + + H L+
Sbjct: 418 NGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLV 452
>AF016369-1|AAC51925.1| 522|Homo sapiens U4/U6 small nuclear
ribonucleoprotein hPrp4 protein.
Length = 522
Score = 90.2 bits (214), Expect = 5e-17
Identities = 71/316 (22%), Positives = 131/316 (41%), Gaps = 15/316 (4%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T QM+ KS ++ ++ D PIS S + ++ A+ C GL ++W + L
Sbjct: 208 TSQMQELH-KSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLL 266
Query: 1002 ATLNGHIGHITCVTFSPNNLLVL--------SGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
TL GH ++ + F P + + L S + D +V +W L + P +GH+ +
Sbjct: 267 HTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRV 326
Query: 1054 QTLLMMSDGRRAMSSDRARNVHVW-LVDSGIVLHSATGPSASIDVTLNMKYAVLSDG--D 1110
++ GR ++ R+ +W L +LH D+ + ++ G D
Sbjct: 327 ARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLD 386
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
R+W L G H + I + + H+ TGS D + KVW L +
Sbjct: 387 AFGRVWDLRTG---RCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 443
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
+ H ++VT V + +++G++D +W KV + ++ D
Sbjct: 444 TIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSD 503
Query: 1231 GTIAVSCAEDKTLIIW 1246
G + +C+ D+T +W
Sbjct: 504 GQLIATCSYDRTFKLW 519
Score = 57.2 bits (132), Expect = 4e-07
Identities = 56/234 (23%), Positives = 93/234 (39%), Gaps = 4/234 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ L P +L + G +LW + S+ V +GH+ + + ++L T D S
Sbjct: 287 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRS 346
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+WDL H V +A + SL +GG D+ + L G + L+ H
Sbjct: 347 WRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGH 406
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHI---FDVTDDNVFL 834
+ + +G TGS D T W++ + T+ A + F+ N FL
Sbjct: 407 LKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGN-FL 465
Query: 835 LTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
LT DN + T + L L H+ KV ++ D +A D+ L+
Sbjct: 466 LTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSP-NNLLVLSGSEDR 1030
+ S +G A+G +VW L R T+ H +T V F P + +L+G+ D
Sbjct: 413 INFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDN 472
Query: 1031 TVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
T +W SP T GH + L + SDG+ + R +W+ +
Sbjct: 473 TAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE 522
Score = 43.2 bits (97), Expect = 0.007
Identities = 31/133 (23%), Positives = 55/133 (41%), Gaps = 1/133 (0%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + + + +GH I + + ++ TGS D + VWDL I H
Sbjct: 390 RVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQ 449
Query: 737 APVLCVA-AIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFIT 795
V V ++ + +++G D+ I + + + L H G V + + DG + T
Sbjct: 450 NLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIAT 509
Query: 796 GSQDGTVCTWNVE 808
S D T W E
Sbjct: 510 CSYDRTFKLWMAE 522
Score = 35.1 bits (77), Expect = 1.9
Identities = 32/155 (20%), Positives = 61/155 (39%), Gaps = 4/155 (2%)
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLS 1169
D SV++WSL D+ E H R+ + + T D S ++W L+ +
Sbjct: 302 DGSVKLWSL---DSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEI 358
Query: 1170 QVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTG 1229
GHS V +A + + +G D VWD+ T ++ + +
Sbjct: 359 LHQEGHSMGVYDIAFH-QDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSP 417
Query: 1230 DGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+G + + D T +W+ ++ + + H L+
Sbjct: 418 NGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLV 452
>AB209797-1|BAD93034.1| 537|Homo sapiens PRPF4 protein variant
protein.
Length = 537
Score = 90.2 bits (214), Expect = 5e-17
Identities = 71/316 (22%), Positives = 131/316 (41%), Gaps = 15/316 (4%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T QM+ KS ++ ++ D PIS S + ++ A+ C GL ++W + L
Sbjct: 223 TSQMQELH-KSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLL 281
Query: 1002 ATLNGHIGHITCVTFSPNNLLVL--------SGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
TL GH ++ + F P + + L S + D +V +W L + P +GH+ +
Sbjct: 282 HTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRV 341
Query: 1054 QTLLMMSDGRRAMSSDRARNVHVW-LVDSGIVLHSATGPSASIDVTLNMKYAVLSDG--D 1110
++ GR ++ R+ +W L +LH D+ + ++ G D
Sbjct: 342 ARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLD 401
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
R+W L G H + I + + H+ TGS D + KVW L +
Sbjct: 402 AFGRVWDLRTG---RCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 458
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
+ H ++VT V + +++G++D +W KV + ++ D
Sbjct: 459 TIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSD 518
Query: 1231 GTIAVSCAEDKTLIIW 1246
G + +C+ D+T +W
Sbjct: 519 GQLIATCSYDRTFKLW 534
Score = 57.2 bits (132), Expect = 4e-07
Identities = 56/234 (23%), Positives = 93/234 (39%), Gaps = 4/234 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ L P +L + G +LW + S+ V +GH+ + + ++L T D S
Sbjct: 302 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRS 361
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+WDL H V +A + SL +GG D+ + L G + L+ H
Sbjct: 362 WRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGH 421
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHI---FDVTDDNVFL 834
+ + +G TGS D T W++ + T+ A + F+ N FL
Sbjct: 422 LKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGN-FL 480
Query: 835 LTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
LT DN + T + L L H+ KV ++ D +A D+ L+
Sbjct: 481 LTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 534
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSP-NNLLVLSGSEDR 1030
+ S +G A+G +VW L R T+ H +T V F P + +L+G+ D
Sbjct: 428 INFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDN 487
Query: 1031 TVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
T +W SP T GH + L + SDG+ + R +W+ +
Sbjct: 488 TAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE 537
Score = 43.2 bits (97), Expect = 0.007
Identities = 31/133 (23%), Positives = 55/133 (41%), Gaps = 1/133 (0%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + + + +GH I + + ++ TGS D + VWDL I H
Sbjct: 405 RVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQ 464
Query: 737 APVLCVA-AIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFIT 795
V V ++ + +++G D+ I + + + L H G V + + DG + T
Sbjct: 465 NLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIAT 524
Query: 796 GSQDGTVCTWNVE 808
S D T W E
Sbjct: 525 CSYDRTFKLWMAE 537
Score = 35.1 bits (77), Expect = 1.9
Identities = 32/155 (20%), Positives = 61/155 (39%), Gaps = 4/155 (2%)
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLS 1169
D SV++WSL D+ E H R+ + + T D S ++W L+ +
Sbjct: 317 DGSVKLWSL---DSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEI 373
Query: 1170 QVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTG 1229
GHS V +A + + +G D VWD+ T ++ + +
Sbjct: 374 LHQEGHSMGVYDIAFH-QDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSP 432
Query: 1230 DGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLL 1264
+G + + D T +W+ ++ + + H L+
Sbjct: 433 NGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLV 467
>CR457279-1|CAG33560.1| 330|Homo sapiens WDR5B protein.
Length = 330
Score = 89.4 bits (212), Expect = 8e-17
Identities = 69/289 (23%), Positives = 126/289 (43%), Gaps = 17/289 (5%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+S ++ S +G+ AS A L+ +W + + TL GH I+ V +S ++ ++S S+
Sbjct: 44 VSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASD 103
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D+T+ +W + T KGHS+ + +S V +W V +G L +
Sbjct: 104 DKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTL 163
Query: 1089 TGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGD----NSEDNRRSVSHAERITCFA 1141
+ S + V N +++ G D RIW A G +D+ VS +
Sbjct: 164 SAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVK------ 217
Query: 1142 LTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAV--SITNKTQVVSGSWDC 1199
+ + ++++T ++D +LK+W G+ + GH + C+ S+T +VSGS D
Sbjct: 218 FSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDN 277
Query: 1200 NLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCA--EDKTLIIW 1246
+ +W++ T V + S A DKT+ +W
Sbjct: 278 LVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTIKLW 326
Score = 88.6 bits (210), Expect = 1e-16
Identities = 71/281 (25%), Positives = 118/281 (41%), Gaps = 13/281 (4%)
Query: 975 SRDG--QLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTV 1032
SRD QL S A V + + L+ TL GH ++ V FSPN + S S DR +
Sbjct: 6 SRDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLI 65
Query: 1033 VVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPS 1092
++W D T GH+ I + SD R +S+ + + +W V SG L + G S
Sbjct: 66 IIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHS 125
Query: 1093 ASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHV 1149
+ N ++ G D +V+IW + G + + +H++ ++ +
Sbjct: 126 NYVFCCNFNPPSNLIISGSFDETVKIWEVKTG---KCLKTLSAHSDPVSAVHFNCSGSLI 182
Query: 1150 VTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTX 1209
V+GS D ++W G+ + LV + N +++ + D L +WD +
Sbjct: 183 VSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRG 242
Query: 1210 XXXXXXXXXXXKVTCV----KVTGDGTIAVSCAEDKTLIIW 1246
+ C+ VTG G VS +ED + IW
Sbjct: 243 RCLKTYTGHKNEKYCIFANFSVTG-GKWIVSGSEDNLVYIW 282
Score = 81.4 bits (192), Expect = 2e-14
Identities = 52/221 (23%), Positives = 95/221 (42%), Gaps = 4/221 (1%)
Query: 967 IPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSG 1026
+ IS + S D S +++W + + + TL GH ++ C F+P + L++SG
Sbjct: 84 LEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISG 143
Query: 1027 SEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH 1086
S D TV +W++ T HS + + G +S +W SG L
Sbjct: 144 SFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLK 203
Query: 1087 SATG----PSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ P + + + N KY + + DN++++W + G + + I
Sbjct: 204 TLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFS 263
Query: 1143 TADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVA 1183
+ +V+GS D + +W L ++ Q L GH+D+V A
Sbjct: 264 VTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAA 304
Score = 79.4 bits (187), Expect = 9e-14
Identities = 58/243 (23%), Positives = 111/243 (45%), Gaps = 8/243 (3%)
Query: 1022 LVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDS 1081
L LS S +++ V + + + T GH+ A+ ++ +G SS R + +W
Sbjct: 13 LALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYD 72
Query: 1082 GIVLHSATGPSASI-DVTLNMKYA--VLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERIT 1138
G + G + I DV + + V + D ++++W + G + + H+ +
Sbjct: 73 GKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLK---GHSNYVF 129
Query: 1139 CFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWD 1198
C S +++GS D ++K+W++ GK + L HSD V+ V + + +VSGS+D
Sbjct: 130 CCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSL-IVSGSYD 188
Query: 1199 CNLIVWDINTXXXXXXXXXXXXK-VTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSF 1257
+WD + V+ VK + +G ++ D TL +W+ RG L ++
Sbjct: 189 GLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTY 248
Query: 1258 SLH 1260
+ H
Sbjct: 249 TGH 251
Score = 73.3 bits (172), Expect = 6e-12
Identities = 53/245 (21%), Positives = 104/245 (42%), Gaps = 5/245 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
++ +P+G+ L + + +W T GH+ I + + +S L++ S+D +
Sbjct: 47 VKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKT 106
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ +WD+ + + H V C +L+ISG D V I + G + L H
Sbjct: 107 LKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAH 166
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT--AGVPIHIFDVTDDNVFLL 835
V++V G++ ++GS DG W+ + L T+ P+ + + ++L
Sbjct: 167 SDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYIL 226
Query: 836 TLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCV---AHDSSRVAVGCADQRIYLYSLHS 892
T DN L L + G L HK + C + G D +Y+++L +
Sbjct: 227 TATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQT 286
Query: 893 AQLLR 897
++++
Sbjct: 287 KEIVQ 291
Score = 51.2 bits (117), Expect = 3e-05
Identities = 31/130 (23%), Positives = 57/130 (43%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T GH+ ++ + + ++L + S D +I+W + + + H + VA +
Sbjct: 36 TLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDS 95
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
S ++S DD + + + G + L H V N+ I+GS D TV W V+
Sbjct: 96 SRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVK 155
Query: 809 NFTLLSTVTA 818
L T++A
Sbjct: 156 TGKCLKTLSA 165
Score = 45.6 bits (103), Expect = 0.001
Identities = 46/196 (23%), Positives = 75/196 (38%), Gaps = 3/196 (1%)
Query: 705 ESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITS 764
++Q L+ S + S V + A+K ++ H V V N + S D +II
Sbjct: 10 KAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWG 69
Query: 765 LVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHI 824
DG L H ++ V D + ++ S D T+ W+V + L T+ G ++
Sbjct: 70 AYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTL-KGHSNYV 128
Query: 825 FDVTDDNVFLLTLQG--DNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCAD 882
F + L + G D + + TG L L H V S + G D
Sbjct: 129 FCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYD 188
Query: 883 QRIYLYSLHSAQLLRT 898
++ S Q L+T
Sbjct: 189 GLCRIWDAASGQCLKT 204
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/99 (23%), Positives = 47/99 (47%), Gaps = 3/99 (3%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRE---SQYLLTGSE 714
++ +P+G++++ A +LW + T+ GH C+ +++++GSE
Sbjct: 216 VKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSE 275
Query: 715 DTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVIS 753
D V +W+L T + K+ H V+ A +L+ S
Sbjct: 276 DNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIAS 314
>BC043494-1|AAH43494.1| 330|Homo sapiens WD repeat domain 5B protein.
Length = 330
Score = 89.4 bits (212), Expect = 8e-17
Identities = 69/289 (23%), Positives = 126/289 (43%), Gaps = 17/289 (5%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+S ++ S +G+ AS A L+ +W + + TL GH I+ V +S ++ ++S S+
Sbjct: 44 VSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASD 103
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D+T+ +W + T KGHS+ + +S V +W V +G L +
Sbjct: 104 DKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTL 163
Query: 1089 TGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGD----NSEDNRRSVSHAERITCFA 1141
+ S + V N +++ G D RIW A G +D+ VS +
Sbjct: 164 SAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVK------ 217
Query: 1142 LTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAV--SITNKTQVVSGSWDC 1199
+ + ++++T ++D +LK+W G+ + GH + C+ S+T +VSGS D
Sbjct: 218 FSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDN 277
Query: 1200 NLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCA--EDKTLIIW 1246
+ +W++ T V + S A DKT+ +W
Sbjct: 278 LVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTIKLW 326
Score = 88.6 bits (210), Expect = 1e-16
Identities = 71/281 (25%), Positives = 118/281 (41%), Gaps = 13/281 (4%)
Query: 975 SRDG--QLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTV 1032
SRD QL S A V + + L+ TL GH ++ V FSPN + S S DR +
Sbjct: 6 SRDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLI 65
Query: 1033 VVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPS 1092
++W D T GH+ I + SD R +S+ + + +W V SG L + G S
Sbjct: 66 IIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHS 125
Query: 1093 ASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHV 1149
+ N ++ G D +V+IW + G + + +H++ ++ +
Sbjct: 126 NYVFCCNFNPPSNLIISGSFDETVKIWEVKTG---KCLKTLSAHSDPVSAVHFNCSGSLI 182
Query: 1150 VTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTX 1209
V+GS D ++W G+ + LV + N +++ + D L +WD +
Sbjct: 183 VSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRG 242
Query: 1210 XXXXXXXXXXXKVTCV----KVTGDGTIAVSCAEDKTLIIW 1246
+ C+ VTG G VS +ED + IW
Sbjct: 243 RCLKTYTGHKNEKYCIFANFSVTG-GKWIVSGSEDNLVYIW 282
Score = 81.4 bits (192), Expect = 2e-14
Identities = 52/221 (23%), Positives = 95/221 (42%), Gaps = 4/221 (1%)
Query: 967 IPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSG 1026
+ IS + S D S +++W + + + TL GH ++ C F+P + L++SG
Sbjct: 84 LEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISG 143
Query: 1027 SEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH 1086
S D TV +W++ T HS + + G +S +W SG L
Sbjct: 144 SFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLK 203
Query: 1087 SATG----PSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ P + + + N KY + + DN++++W + G + + I
Sbjct: 204 TLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFS 263
Query: 1143 TADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVA 1183
+ +V+GS D + +W L ++ Q L GH+D+V A
Sbjct: 264 VTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAA 304
Score = 79.4 bits (187), Expect = 9e-14
Identities = 58/243 (23%), Positives = 111/243 (45%), Gaps = 8/243 (3%)
Query: 1022 LVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDS 1081
L LS S +++ V + + + T GH+ A+ ++ +G SS R + +W
Sbjct: 13 LALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYD 72
Query: 1082 GIVLHSATGPSASI-DVTLNMKYA--VLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERIT 1138
G + G + I DV + + V + D ++++W + G + + H+ +
Sbjct: 73 GKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLK---GHSNYVF 129
Query: 1139 CFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWD 1198
C S +++GS D ++K+W++ GK + L HSD V+ V + + +VSGS+D
Sbjct: 130 CCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSL-IVSGSYD 188
Query: 1199 CNLIVWDINTXXXXXXXXXXXXK-VTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSF 1257
+WD + V+ VK + +G ++ D TL +W+ RG L ++
Sbjct: 189 GLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTY 248
Query: 1258 SLH 1260
+ H
Sbjct: 249 TGH 251
Score = 73.3 bits (172), Expect = 6e-12
Identities = 53/245 (21%), Positives = 104/245 (42%), Gaps = 5/245 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
++ +P+G+ L + + +W T GH+ I + + +S L++ S+D +
Sbjct: 47 VKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKT 106
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ +WD+ + + H V C +L+ISG D V I + G + L H
Sbjct: 107 LKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAH 166
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT--AGVPIHIFDVTDDNVFLL 835
V++V G++ ++GS DG W+ + L T+ P+ + + ++L
Sbjct: 167 SDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYIL 226
Query: 836 TLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCV---AHDSSRVAVGCADQRIYLYSLHS 892
T DN L L + G L HK + C + G D +Y+++L +
Sbjct: 227 TATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQT 286
Query: 893 AQLLR 897
++++
Sbjct: 287 KEIVQ 291
Score = 51.2 bits (117), Expect = 3e-05
Identities = 31/130 (23%), Positives = 57/130 (43%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T GH+ ++ + + ++L + S D +I+W + + + H + VA +
Sbjct: 36 TLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDS 95
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
S ++S DD + + + G + L H V N+ I+GS D TV W V+
Sbjct: 96 SRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVK 155
Query: 809 NFTLLSTVTA 818
L T++A
Sbjct: 156 TGKCLKTLSA 165
Score = 45.6 bits (103), Expect = 0.001
Identities = 46/196 (23%), Positives = 75/196 (38%), Gaps = 3/196 (1%)
Query: 705 ESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITS 764
++Q L+ S + S V + A+K ++ H V V N + S D +II
Sbjct: 10 KAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWG 69
Query: 765 LVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHI 824
DG L H ++ V D + ++ S D T+ W+V + L T+ G ++
Sbjct: 70 AYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTL-KGHSNYV 128
Query: 825 FDVTDDNVFLLTLQG--DNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCAD 882
F + L + G D + + TG L L H V S + G D
Sbjct: 129 FCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYD 188
Query: 883 QRIYLYSLHSAQLLRT 898
++ S Q L+T
Sbjct: 189 GLCRIWDAASGQCLKT 204
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/99 (23%), Positives = 47/99 (47%), Gaps = 3/99 (3%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRE---SQYLLTGSE 714
++ +P+G++++ A +LW + T+ GH C+ +++++GSE
Sbjct: 216 VKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSE 275
Query: 715 DTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVIS 753
D V +W+L T + K+ H V+ A +L+ S
Sbjct: 276 DNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIAS 314
>AK098821-1|BAC05425.1| 415|Homo sapiens protein ( Homo sapiens cDNA
FLJ25955 fis, clone TST03904. ).
Length = 415
Score = 88.6 bits (210), Expect = 1e-16
Identities = 63/307 (20%), Positives = 125/307 (40%), Gaps = 8/307 (2%)
Query: 958 LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTF- 1016
L + ++ ++P++ + +++ G +G ++W ++ TL GH + + F
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFN 143
Query: 1017 SPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHV 1076
+P + +GS D+T +W + T++GH++ I L + +
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKL 203
Query: 1077 WLVDSGIVLHSATGPSAS-IDVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSH 1133
W + +G +++ G SA I ++ N + G D++V +W D + H
Sbjct: 204 WDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWD---ADTGRKVNILIGH 260
Query: 1134 AERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVV 1193
I+ + D ++TGSMD + K+W GK L GH D + T K +
Sbjct: 261 CAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKL-IA 319
Query: 1194 SGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLA 1253
+ S D ++ T +++ + G ++ + DKT IW+ + G
Sbjct: 320 TASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQC 379
Query: 1254 LTSFSLH 1260
L H
Sbjct: 380 LQVLEGH 386
Score = 87.8 bits (208), Expect = 2e-16
Identities = 62/270 (22%), Positives = 115/270 (42%), Gaps = 11/270 (4%)
Query: 982 ASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNS 1041
A+G ++W + T + T GH I C++F+P + LV +GS D T +W + +
Sbjct: 151 ATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGE 210
Query: 1042 PSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLN 1100
T +GHS+ I +L + G R ++ V VW D+G ++ G A I + N
Sbjct: 211 EVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFN 270
Query: 1101 MKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERI--TCFALTADSQHVVTGSMDM 1156
+++ G D + ++W N + H + I +CF T + + T S D
Sbjct: 271 WDCSLILTGSMDKTCKLWD---ATNGKCVATLTGHDDEILDSCFDYT--GKLIATASADG 325
Query: 1157 SLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXX 1216
+ +++ K L GH ++ ++ + +++GS D +WD T
Sbjct: 326 TARIFSAATRKCIAKLEGHEGEISKISFN-PQGNHLLTGSSDKTARIWDAQTGQCLQVLE 384
Query: 1217 XXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
++ G I ++ ++ T IW
Sbjct: 385 GHTDEIFSCAFNYKGNIVITGSKGNTCRIW 414
Score = 84.2 bits (199), Expect = 3e-15
Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 3/223 (1%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
+LW + + HTF+GH+ I+C+ +S + TGS DT+ +WD+ + H
Sbjct: 160 KLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHS 219
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A ++ ++ + +I+G D V++ G V L H ++S D ++ +TG
Sbjct: 220 AEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTG 279
Query: 797 SQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDD--NVFLLTLQGDNELHLRTFITGTYL 854
S D T W+ N ++T+T G I D D + T D + + T +
Sbjct: 280 SMDKTCKLWDATNGKCVATLT-GHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCI 338
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
L+ H+ ++ + + G +D+ ++ + Q L+
Sbjct: 339 AKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQ 381
Score = 79.8 bits (188), Expect = 7e-14
Identities = 49/213 (23%), Positives = 98/213 (46%), Gaps = 8/213 (3%)
Query: 997 THRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTL 1056
T L L HI +T V + + ++GS DRT +W A T +GH + + +
Sbjct: 81 TFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAI 140
Query: 1057 LMMSD-GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDG--DNS 1112
+ G + + + +W V++G H+ G +A I ++ N + +++ G D +
Sbjct: 141 AFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTT 200
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
++W + G+ R H+ I + ++TGS D ++ VW D G+ +L
Sbjct: 201 AKLWDIQNGEEVYTLR---GHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNIL 257
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+GH ++ + + + + +++GS D +WD
Sbjct: 258 IGHCAEISSASFN-WDCSLILTGSMDKTCKLWD 289
Score = 77.8 bits (183), Expect = 3e-13
Identities = 57/239 (23%), Positives = 98/239 (41%), Gaps = 7/239 (2%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I CL + L A+G ++W + TL GH I ++F+ + +++GS
Sbjct: 180 IVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSF 239
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D TVVVW GH + I + D ++ + +W +G + +
Sbjct: 240 DHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATL 299
Query: 1089 TGPSASI-DVTLNM--KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
TG I D + K + D + RI+S A + + H I+ +
Sbjct: 300 TGHDDEILDSCFDYTGKLIATASADGTARIFSAA---TRKCIAKLEGHEGEISKISFNPQ 356
Query: 1146 SQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
H++TGS D + ++W G+ QVL GH+D + A + V++GS +W
Sbjct: 357 GNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNI-VITGSKGNTCRIW 414
Score = 72.9 bits (171), Expect = 8e-12
Identities = 75/331 (22%), Positives = 134/331 (40%), Gaps = 31/331 (9%)
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVF 833
L H +T+V + + G+ FITGS D T W+ + L+T+ + ++ + +N +
Sbjct: 88 LKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNV-VYAIAFNNPY 146
Query: 834 ---LLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCAD-------- 882
+ T D L + TG H + H A++ C S+ VA G D
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI 206
Query: 883 ---QRIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLL--AAGGNRVTIYSFH-TEDNL 936
+ +Y HSA+++ ++ A G +V I H E +
Sbjct: 207 QNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISS 266
Query: 937 TNFR------PTKQM-KRRQTKSTTN---ITLLQAEQSDLIPISCLEVSRDGQLGASGCA 986
+F T M K + TN + L +++ SC + + G+L A+ A
Sbjct: 267 ASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILD-SCFDYT--GKLIATASA 323
Query: 987 RGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTY 1046
G R++ +T + A L GH G I+ ++F+P +L+GS D+T +W
Sbjct: 324 DGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVL 383
Query: 1047 KGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
+GH+ I + G ++ + +W
Sbjct: 384 EGHTDEIFSCAFNYKGNIVITGSKGNTCRIW 414
Score = 61.3 bits (142), Expect = 2e-08
Identities = 47/215 (21%), Positives = 84/215 (39%), Gaps = 2/215 (0%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRE-SQYLLTGSEDTSVIVWDLHTLAVKTKILEH 735
+LW S +++T +GH + + + TGS D + +W + T H
Sbjct: 117 KLWDSASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGH 176
Query: 736 IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFIT 795
A ++C++ +LV +G D+ + + +G V L H + S+ G+ IT
Sbjct: 177 TAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIIT 236
Query: 796 GSQDGTVCTWNVENFTLLSTVTAG-VPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYL 854
GS D TV W+ + ++ + I D +LT D L G +
Sbjct: 237 GSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCV 296
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
L H ++ C + +A AD ++S
Sbjct: 297 ATLTGHDDEILDSCFDYTGKLIATASADGTARIFS 331
Score = 58.4 bits (135), Expect = 2e-07
Identities = 35/161 (21%), Positives = 66/161 (40%), Gaps = 7/161 (4%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQ 1191
+H +T AL +TGS D + K+W G+ L GH ++V +A + +
Sbjct: 90 AHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPYGDK 149
Query: 1192 VVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ +GS+D +W + T ++ C+ T+ + + D T +W+ + G
Sbjct: 150 IATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNG 209
Query: 1252 ---LALTSFSLHVPLLGFQITSDCARVVVHLLDRGCLPIIW 1289
L S + L F + D R++ D ++W
Sbjct: 210 EEVYTLRGHSAEIISLSFNTSGD--RIITGSFDH--TVVVW 246
Score = 55.2 bits (127), Expect = 2e-06
Identities = 34/151 (22%), Positives = 55/151 (36%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L SG ++ +W + KV+ GH I + +LTGS D +
Sbjct: 225 LSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKT 284
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+WD + H +L L+ + D I S + KL+ H
Sbjct: 285 CKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGH 344
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
G ++ + GN +TGS D T W+ +
Sbjct: 345 EGEISKISFNPQGNHLLTGSSDKTARIWDAQ 375
Score = 50.8 bits (116), Expect = 4e-05
Identities = 42/197 (21%), Positives = 73/197 (37%), Gaps = 6/197 (3%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I L + G +G V VW T R L GH I+ +F+ + L+L+GS
Sbjct: 222 IISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSM 281
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D+T +W + T GH I G+ ++ ++ + +
Sbjct: 282 DKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKL 341
Query: 1089 TGPSASID-VTLNMK--YAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
G I ++ N + + + D + RIW G + H + I A
Sbjct: 342 EGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLE---GHTDEIFSCAFNYK 398
Query: 1146 SQHVVTGSMDMSLKVWK 1162
V+TGS + ++W+
Sbjct: 399 GNIVITGSKGNTCRIWR 415
Score = 48.4 bits (110), Expect = 2e-04
Identities = 31/129 (24%), Positives = 50/129 (38%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
+LW + V T GH IL C + + T S D + ++ T K+ H
Sbjct: 286 KLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHE 345
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
+ ++ + +++G D I G + L+ H + S GNI ITG
Sbjct: 346 GEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITG 405
Query: 797 SQDGTVCTW 805
S+ T W
Sbjct: 406 SKGNTCRIW 414
Score = 43.6 bits (98), Expect = 0.005
Identities = 66/351 (18%), Positives = 125/351 (35%), Gaps = 29/351 (8%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVN--R 748
K H + + + + +TGS D + +WD + LE V+ A N
Sbjct: 89 KAHILPLTNVALNKSGSCFITGSYDRTCKLWD-SASGEELNTLEGHRNVVYAIAFNNPYG 147
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
+ +G D + S+ G H + + + TGS D T W+++
Sbjct: 148 DKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQ 207
Query: 809 NFTLLSTV---TAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVK 865
N + T+ +A + F+ + D + +T D+ + + TG ++ L H A++
Sbjct: 208 NGEEVYTLRGHSAEIISLSFNTSGDRI--ITGSFDHTVVVWDADTGRKVNILIGHCAEIS 265
Query: 866 CFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRV 925
D S + G D+ L+ + + + T L+A
Sbjct: 266 SASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADG 325
Query: 926 TIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGC 985
T F T++ I L+ + + IS + + G +G
Sbjct: 326 TARIFSA--------ATRKC----------IAKLEGHEGE---ISKISFNPQGNHLLTGS 364
Query: 986 ARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQ 1036
+ R+W T + L GH I F+ +V++GS+ T +W+
Sbjct: 365 SDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKGNTCRIWR 415
Score = 39.1 bits (87), Expect = 0.11
Identities = 21/92 (22%), Positives = 41/92 (44%)
Query: 663 SGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWD 722
+G+ + A + G +++ + + +GH G I + + +LLTGS D + +WD
Sbjct: 314 TGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWD 373
Query: 723 LHTLAVKTKILEHIAPVLCVAAIVNRSLVISG 754
T + H + A ++VI+G
Sbjct: 374 AQTGQCLQVLEGHTDEIFSCAFNYKGNIVITG 405
Score = 34.7 bits (76), Expect = 2.5
Identities = 13/60 (21%), Positives = 26/60 (43%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVW 721
P G HL+ S ++W + + +GH+ I + ++TGS+ + +W
Sbjct: 355 PQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKGNTCRIW 414
>AK002149-1|BAA92110.1| 330|Homo sapiens protein ( Homo sapiens cDNA
FLJ11287 fis, clone PLACE1009596, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 330
Score = 88.6 bits (210), Expect = 1e-16
Identities = 71/281 (25%), Positives = 118/281 (41%), Gaps = 13/281 (4%)
Query: 975 SRDG--QLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTV 1032
SRD QL S A V + + L+ TL GH ++ V FSPN + S S DR +
Sbjct: 6 SRDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLI 65
Query: 1033 VVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPS 1092
++W D T GH+ I + SD R +S+ + + +W V SG L + G S
Sbjct: 66 IIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHS 125
Query: 1093 ASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHV 1149
+ N ++ G D +V+IW + G + + +H++ ++ +
Sbjct: 126 NYVFCCNFNPPSNLIISGSFDETVKIWEVKTG---KCLKTLSAHSDPVSAVHFNCSGSLI 182
Query: 1150 VTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTX 1209
V+GS D ++W G+ + LV + N +++ + D L +WD +
Sbjct: 183 VSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRG 242
Query: 1210 XXXXXXXXXXXKVTCV----KVTGDGTIAVSCAEDKTLIIW 1246
+ C+ VTG G VS +ED + IW
Sbjct: 243 RCLKTYTGQKNEKYCIFANFSVTG-GKWIVSGSEDNLVYIW 282
Score = 86.2 bits (204), Expect = 8e-16
Identities = 68/289 (23%), Positives = 125/289 (43%), Gaps = 17/289 (5%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+S ++ S +G+ AS A L+ +W + + TL GH I+ V +S ++ ++S S+
Sbjct: 44 VSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASD 103
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D+T+ +W + T KGHS+ + +S V +W V +G L +
Sbjct: 104 DKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTL 163
Query: 1089 TGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGD----NSEDNRRSVSHAERITCFA 1141
+ S + V N +++ G D RIW A G +D+ VS +
Sbjct: 164 SAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVK------ 217
Query: 1142 LTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAV--SITNKTQVVSGSWDC 1199
+ + ++++T ++D +LK+W G+ + G + C+ S+T +VSGS D
Sbjct: 218 FSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGQKNEKYCIFANFSVTGGKWIVSGSEDN 277
Query: 1200 NLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCA--EDKTLIIW 1246
+ +W++ T V + S A DKT+ +W
Sbjct: 278 LVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTIKLW 326
Score = 81.8 bits (193), Expect = 2e-14
Identities = 52/221 (23%), Positives = 95/221 (42%), Gaps = 4/221 (1%)
Query: 967 IPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSG 1026
+ IS + S D S +++W + + + TL GH ++ C F+P + L++SG
Sbjct: 84 LEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISG 143
Query: 1027 SEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH 1086
S D TV +W++ T HS + + G +S +W SG L
Sbjct: 144 SFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLK 203
Query: 1087 SATG----PSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ P + + + N KY + + DN++++W + G + + I
Sbjct: 204 TLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGQKNEKYCIFANFS 263
Query: 1143 TADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVA 1183
+ +V+GS D + +W L ++ Q L GH+D+V A
Sbjct: 264 VTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAA 304
Score = 77.8 bits (183), Expect = 3e-13
Identities = 57/241 (23%), Positives = 110/241 (45%), Gaps = 8/241 (3%)
Query: 1022 LVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDS 1081
L LS S +++ V + + + T GH+ A+ ++ +G SS R + +W
Sbjct: 13 LALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYD 72
Query: 1082 GIVLHSATGPSASI-DVTLNMKYA--VLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERIT 1138
G + G + I DV + + V + D ++++W + G + + H+ +
Sbjct: 73 GKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLK---GHSNYVF 129
Query: 1139 CFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWD 1198
C S +++GS D ++K+W++ GK + L HSD V+ V + + +VSGS+D
Sbjct: 130 CCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSL-IVSGSYD 188
Query: 1199 CNLIVWDINTXXXXXXXXXXXXK-VTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSF 1257
+WD + V+ VK + +G ++ D TL +W+ RG L ++
Sbjct: 189 GLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTY 248
Query: 1258 S 1258
+
Sbjct: 249 T 249
Score = 70.1 bits (164), Expect = 5e-11
Identities = 52/245 (21%), Positives = 103/245 (42%), Gaps = 5/245 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
++ +P+G+ L + + +W T GH+ I + + +S L++ S+D +
Sbjct: 47 VKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKT 106
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ +WD+ + + H V C +L+ISG D V I + G + L H
Sbjct: 107 LKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAH 166
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT--AGVPIHIFDVTDDNVFLL 835
V++V G++ ++GS DG W+ + L T+ P+ + + ++L
Sbjct: 167 SDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYIL 226
Query: 836 TLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCV---AHDSSRVAVGCADQRIYLYSLHS 892
T DN L L + G L K + C + G D +Y+++L +
Sbjct: 227 TATLDNTLKLWDYSRGRCLKTYTGQKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQT 286
Query: 893 AQLLR 897
++++
Sbjct: 287 KEIVQ 291
Score = 60.9 bits (141), Expect = 3e-08
Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 1/130 (0%)
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKT 1190
V H E ++ + + + + + S D + +W GK + L GH+ ++ VA S ++ +
Sbjct: 38 VGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWS-SDSS 96
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
++VS S D L +WD+ + V C + +S + D+T+ IWE K
Sbjct: 97 RLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKT 156
Query: 1251 GLALTSFSLH 1260
G L + S H
Sbjct: 157 GKCLKTLSAH 166
Score = 51.2 bits (117), Expect = 3e-05
Identities = 31/130 (23%), Positives = 57/130 (43%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T GH+ ++ + + ++L + S D +I+W + + + H + VA +
Sbjct: 36 TLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDS 95
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
S ++S DD + + + G + L H V N+ I+GS D TV W V+
Sbjct: 96 SRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVK 155
Query: 809 NFTLLSTVTA 818
L T++A
Sbjct: 156 TGKCLKTLSA 165
Score = 45.6 bits (103), Expect = 0.001
Identities = 46/196 (23%), Positives = 75/196 (38%), Gaps = 3/196 (1%)
Query: 705 ESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITS 764
++Q L+ S + S V + A+K ++ H V V N + S D +II
Sbjct: 10 KAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWG 69
Query: 765 LVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHI 824
DG L H ++ V D + ++ S D T+ W+V + L T+ G ++
Sbjct: 70 AYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTL-KGHSNYV 128
Query: 825 FDVTDDNVFLLTLQG--DNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCAD 882
F + L + G D + + TG L L H V S + G D
Sbjct: 129 FCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYD 188
Query: 883 QRIYLYSLHSAQLLRT 898
++ S Q L+T
Sbjct: 189 GLCRIWDAASGQCLKT 204
Score = 42.3 bits (95), Expect = 0.012
Identities = 22/99 (22%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRE---SQYLLTGSE 714
++ +P+G++++ A +LW + T+ G C+ +++++GSE
Sbjct: 216 VKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGQKNEKYCIFANFSVTGGKWIVSGSE 275
Query: 715 DTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVIS 753
D V +W+L T + K+ H V+ A +L+ S
Sbjct: 276 DNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIAS 314
>BC028628-1|AAH28628.1| 375|Homo sapiens WDR71 protein protein.
Length = 375
Score = 87.0 bits (206), Expect = 4e-16
Identities = 38/109 (34%), Positives = 58/109 (53%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+CL++S G LG S G +++WQ S L+ L GH+ + C F P+ L+VLSG
Sbjct: 78 ITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVLSGGM 137
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
D + +W D S +T+KGH I ++ GR +S+ R +W
Sbjct: 138 DAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLW 186
Score = 56.0 bits (129), Expect = 9e-07
Identities = 27/114 (23%), Positives = 54/114 (47%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ SI C+ ++ ++ S D ++ +W ++ + H+ V C + +V+
Sbjct: 74 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVL 133
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
SGG D+ + I S D + V H+G + ++ G ++ S+DGT W+
Sbjct: 134 SGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWD 187
Score = 53.6 bits (123), Expect = 5e-06
Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 1/122 (0%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H + ITC +++ V+ S D ++K+W+ G+L +VL GH V C + V
Sbjct: 74 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRF-FPSGLVV 132
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
+SG D L +W + + G VS + D T +W+ R
Sbjct: 133 LSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWDCGRSA 192
Query: 1253 AL 1254
L
Sbjct: 193 CL 194
Score = 43.6 bits (98), Expect = 0.005
Identities = 28/111 (25%), Positives = 44/111 (39%), Gaps = 4/111 (3%)
Query: 1095 IDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSM 1154
+D++ V S D +++IW + G E R H + C V++G M
Sbjct: 81 LDISSRGGLGVSSSTDGTMKIWQASNG---ELRRVLEGHVFDVNCCRFFPSGLVVLSGGM 137
Query: 1155 DMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
D LK+W + GH + A+ + VVS S D +WD
Sbjct: 138 DAQLKIWSAEDASCVVTFKGHKGGILDTAI-VDRGRNVVSASRDGTARLWD 187
Score = 37.5 bits (83), Expect = 0.35
Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Query: 662 PSGQHLVLAPSAGDPQL--WHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
PSG LV+ D QL W S V TFKGH G IL + + +++ S D +
Sbjct: 127 PSG--LVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTAR 184
Query: 720 VWD 722
+WD
Sbjct: 185 LWD 187
Score = 37.1 bits (82), Expect = 0.46
Identities = 24/113 (21%), Positives = 43/113 (38%), Gaps = 3/113 (2%)
Query: 1007 HIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAM 1066
H ITC+ S L +S S D T+ +WQ ++ +GH + G +
Sbjct: 74 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVL 133
Query: 1067 SSDRARNVHVWLVDSGIVLHSATGPSASI-DVTL--NMKYAVLSDGDNSVRIW 1116
S + +W + + + G I D + + V + D + R+W
Sbjct: 134 SGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLW 186
>BC021541-1|AAH21541.1| 392|Homo sapiens WD repeat domain 71 protein.
Length = 392
Score = 87.0 bits (206), Expect = 4e-16
Identities = 38/109 (34%), Positives = 58/109 (53%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+CL++S G LG S G +++WQ S L+ L GH+ + C F P+ L+VLSG
Sbjct: 95 ITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVLSGGM 154
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
D + +W D S +T+KGH I ++ GR +S+ R +W
Sbjct: 155 DAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLW 203
Score = 56.0 bits (129), Expect = 9e-07
Identities = 27/114 (23%), Positives = 54/114 (47%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ SI C+ ++ ++ S D ++ +W ++ + H+ V C + +V+
Sbjct: 91 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVL 150
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
SGG D+ + I S D + V H+G + ++ G ++ S+DGT W+
Sbjct: 151 SGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWD 204
Score = 52.4 bits (120), Expect = 1e-05
Identities = 30/118 (25%), Positives = 49/118 (41%), Gaps = 1/118 (0%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H + ITC +++ V+ S D ++K+W+ G+L +VL GH V C + V
Sbjct: 91 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRF-FPSGLVV 149
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
+SG D L +W + + G VS + D T +W+ R
Sbjct: 150 LSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWDCGR 207
Score = 43.6 bits (98), Expect = 0.005
Identities = 28/111 (25%), Positives = 44/111 (39%), Gaps = 4/111 (3%)
Query: 1095 IDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSM 1154
+D++ V S D +++IW + G E R H + C V++G M
Sbjct: 98 LDISSRGGLGVSSSTDGTMKIWQASNG---ELRRVLEGHVFDVNCCRFFPSGLVVLSGGM 154
Query: 1155 DMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
D LK+W + GH + A+ + VVS S D +WD
Sbjct: 155 DAQLKIWSAEDASCVVTFKGHKGGILDTAI-VDRGRNVVSASRDGTARLWD 204
Score = 37.5 bits (83), Expect = 0.35
Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Query: 662 PSGQHLVLAPSAGDPQL--WHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
PSG LV+ D QL W S V TFKGH G IL + + +++ S D +
Sbjct: 144 PSG--LVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTAR 201
Query: 720 VWD 722
+WD
Sbjct: 202 LWD 204
Score = 37.1 bits (82), Expect = 0.46
Identities = 24/113 (21%), Positives = 43/113 (38%), Gaps = 3/113 (2%)
Query: 1007 HIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAM 1066
H ITC+ S L +S S D T+ +WQ ++ +GH + G +
Sbjct: 91 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVL 150
Query: 1067 SSDRARNVHVWLVDSGIVLHSATGPSASI-DVTL--NMKYAVLSDGDNSVRIW 1116
S + +W + + + G I D + + V + D + R+W
Sbjct: 151 SGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLW 203
>BC006142-1|AAH06142.2| 392|Homo sapiens WD repeat domain 71 protein.
Length = 392
Score = 87.0 bits (206), Expect = 4e-16
Identities = 38/109 (34%), Positives = 58/109 (53%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+CL++S G LG S G +++WQ S L+ L GH+ + C F P+ L+VLSG
Sbjct: 95 ITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVLSGGM 154
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
D + +W D S +T+KGH I ++ GR +S+ R +W
Sbjct: 155 DAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLW 203
Score = 56.0 bits (129), Expect = 9e-07
Identities = 27/114 (23%), Positives = 54/114 (47%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ SI C+ ++ ++ S D ++ +W ++ + H+ V C + +V+
Sbjct: 91 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVL 150
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
SGG D+ + I S D + V H+G + ++ G ++ S+DGT W+
Sbjct: 151 SGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWD 204
Score = 53.6 bits (123), Expect = 5e-06
Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 1/122 (0%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H + ITC +++ V+ S D ++K+W+ G+L +VL GH V C + V
Sbjct: 91 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRF-FPSGLVV 149
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
+SG D L +W + + G VS + D T +W+ R
Sbjct: 150 LSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWDCGRSA 209
Query: 1253 AL 1254
L
Sbjct: 210 CL 211
Score = 43.6 bits (98), Expect = 0.005
Identities = 28/111 (25%), Positives = 44/111 (39%), Gaps = 4/111 (3%)
Query: 1095 IDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSM 1154
+D++ V S D +++IW + G E R H + C V++G M
Sbjct: 98 LDISSRGGLGVSSSTDGTMKIWQASNG---ELRRVLEGHVFDVNCCRFFPSGLVVLSGGM 154
Query: 1155 DMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
D LK+W + GH + A+ + VVS S D +WD
Sbjct: 155 DAQLKIWSAEDASCVVTFKGHKGGILDTAI-VDRGRNVVSASRDGTARLWD 204
Score = 37.5 bits (83), Expect = 0.35
Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Query: 662 PSGQHLVLAPSAGDPQL--WHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
PSG LV+ D QL W S V TFKGH G IL + + +++ S D +
Sbjct: 144 PSG--LVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTAR 201
Query: 720 VWD 722
+WD
Sbjct: 202 LWD 204
Score = 37.1 bits (82), Expect = 0.46
Identities = 24/113 (21%), Positives = 43/113 (38%), Gaps = 3/113 (2%)
Query: 1007 HIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAM 1066
H ITC+ S L +S S D T+ +WQ ++ +GH + G +
Sbjct: 91 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVL 150
Query: 1067 SSDRARNVHVWLVDSGIVLHSATGPSASI-DVTL--NMKYAVLSDGDNSVRIW 1116
S + +W + + + G I D + + V + D + R+W
Sbjct: 151 SGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLW 203
>AK021910-1|BAB13933.1| 392|Homo sapiens protein ( Homo sapiens cDNA
FLJ11848 fis, clone HEMBA1006708, weakly similar to
HYPOTHETICAL 46.4 KD TRP-ASP REPEATS CONTAINING PROTEIN
IN ).
Length = 392
Score = 87.0 bits (206), Expect = 4e-16
Identities = 38/109 (34%), Positives = 58/109 (53%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+CL++S G LG S G +++WQ S L+ L GH+ + C F P+ L+VLSG
Sbjct: 95 ITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVLSGGM 154
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
D + +W D S +T+KGH I ++ GR +S+ R +W
Sbjct: 155 DAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLW 203
Score = 56.0 bits (129), Expect = 9e-07
Identities = 27/114 (23%), Positives = 54/114 (47%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ SI C+ ++ ++ S D ++ +W ++ + H+ V C + +V+
Sbjct: 91 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVL 150
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
SGG D+ + I S D + V H+G + ++ G ++ S+DGT W+
Sbjct: 151 SGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWD 204
Score = 53.6 bits (123), Expect = 5e-06
Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 1/122 (0%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H + ITC +++ V+ S D ++K+W+ G+L +VL GH V C + V
Sbjct: 91 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRF-FPSGLVV 149
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
+SG D L +W + + G VS + D T +W+ R
Sbjct: 150 LSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWDCGRSA 209
Query: 1253 AL 1254
L
Sbjct: 210 CL 211
Score = 43.6 bits (98), Expect = 0.005
Identities = 28/111 (25%), Positives = 44/111 (39%), Gaps = 4/111 (3%)
Query: 1095 IDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSM 1154
+D++ V S D +++IW + G E R H + C V++G M
Sbjct: 98 LDISSRGGLGVSSSTDGTMKIWQASNG---ELRRVLEGHVFDVNCCRFFPSGLVVLSGGM 154
Query: 1155 DMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
D LK+W + GH + A+ + VVS S D +WD
Sbjct: 155 DAQLKIWSAEDASCVVTFKGHKGGILDTAI-VDRGRNVVSASRDGTARLWD 204
Score = 37.5 bits (83), Expect = 0.35
Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Query: 662 PSGQHLVLAPSAGDPQL--WHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
PSG LV+ D QL W S V TFKGH G IL + + +++ S D +
Sbjct: 144 PSG--LVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTAR 201
Query: 720 VWD 722
+WD
Sbjct: 202 LWD 204
Score = 37.1 bits (82), Expect = 0.46
Identities = 24/113 (21%), Positives = 43/113 (38%), Gaps = 3/113 (2%)
Query: 1007 HIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAM 1066
H ITC+ S L +S S D T+ +WQ ++ +GH + G +
Sbjct: 91 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVL 150
Query: 1067 SSDRARNVHVWLVDSGIVLHSATGPSASI-DVTL--NMKYAVLSDGDNSVRIW 1116
S + +W + + + G I D + + V + D + R+W
Sbjct: 151 SGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLW 203
>AF090988-1|AAC69625.1| 357|Homo sapiens U5 snRNP-specific 40 kDa
protein protein.
Length = 357
Score = 87.0 bits (206), Expect = 4e-16
Identities = 51/208 (24%), Positives = 99/208 (47%), Gaps = 10/208 (4%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL-ADNSPSLTYKGHSSAIQTLLMMSDG 1062
L+GH G + C F PN + S DR +++W + D T KGHS A+ L +DG
Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121
Query: 1063 RRAMSSDRARNVHVWLVDSGIVLHSATGPSASID----VTLNMKYAVLSDGDNSVRIWSL 1118
S+ + V VW ++G + G ++ ++ + + D +V++W +
Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDDGTVKLWDI 181
Query: 1119 AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDI 1178
+ ++ + ++ S +++G +D +KVW L KL+ + GH+D
Sbjct: 182 ----RKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADS 237
Query: 1179 VTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
VT +++S + + ++S + D + VWD+
Sbjct: 238 VTGLSLS-SEGSYLLSNAMDNTVRVWDV 264
Score = 66.5 bits (155), Expect = 7e-10
Identities = 60/290 (20%), Positives = 122/290 (42%), Gaps = 14/290 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQL-STHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
+ C + +G AS L+ +W + ATL GH G + + ++ + ++ S S
Sbjct: 69 VYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSAS 128
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLL-MMSDGRRAMSSDRARNVHVWLVDSGIVLH 1086
D+TV VW KGH+S + + + + V +W + +
Sbjct: 129 TDKTVAVWDSETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDDGTVKLWDIRKKAAIQ 188
Query: 1087 SATGPSASIDVTLN-MKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTA 1144
+ + VT N ++S G DN +++W L + R HA+ +T +L++
Sbjct: 189 TFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMR---GHADSVTGLSLSS 245
Query: 1145 DSQHVVTGSMDMSLKVWKL----DGGKLSQVLVG--HSDIVTCVAVSIT-NKTQVVSGSW 1197
+ ++++ +MD +++VW + + ++ G H+ + S + + +++ +GS
Sbjct: 246 EGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSA 305
Query: 1198 DCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
D + VWD + + V D I +S + DK L + E
Sbjct: 306 DRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGE 355
Score = 64.5 bits (150), Expect = 3e-09
Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 2/148 (1%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSI-LCMCVTRESQYLLTGSEDTSVIVWD 722
G L A + +W + +V KGH+ + C + Q + TGS+D +V +WD
Sbjct: 121 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDDGTVKLWD 180
Query: 723 LHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ A + ++ VL V +ISGG D+ + + L L + H SVT
Sbjct: 181 IRKKAA-IQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVT 239
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVENF 810
+ + +G+ ++ + D TV W+V F
Sbjct: 240 GLSLSSEGSYLLSNAMDNTVRVWDVRPF 267
Score = 56.4 bits (130), Expect = 7e-07
Identities = 43/215 (20%), Positives = 88/215 (40%), Gaps = 12/215 (5%)
Query: 1041 SPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLV----DSGIVLHSATGPSASID 1096
+P + GH + +G S+ R + +W V D+ L +G +
Sbjct: 57 APIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELH 116
Query: 1097 VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI-TCFALTADSQHVVTGSMD 1155
+ + D +V +W + E +R H + +C+ Q V TGS D
Sbjct: 117 YNTDGSMLFSASTDKTVAVWD---SETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDD 173
Query: 1156 MSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKT-QVVSGSWDCNLIVWDINTXXXXXX 1214
++K+W + + + + +AV+ + + Q++SG D ++ VWD+
Sbjct: 174 GTVKLWDI---RKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYT 230
Query: 1215 XXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
VT + ++ +G+ +S A D T+ +W+ +
Sbjct: 231 MRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVR 265
Score = 55.2 bits (127), Expect = 2e-06
Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 8/133 (6%)
Query: 675 DPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE 734
D ++W + N +T +GH+ S+ + ++ E YLL+ + D +V VWD+ A K + ++
Sbjct: 216 DIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVK 275
Query: 735 HI--------APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
+L + + S + +G D V + ++ KL H GS+ V
Sbjct: 276 IFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAF 335
Query: 787 IQDGNIFITGSQD 799
D I I+ S D
Sbjct: 336 HPDEPIIISASSD 348
Score = 54.4 bits (125), Expect = 3e-06
Identities = 56/247 (22%), Positives = 105/247 (42%), Gaps = 14/247 (5%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVH-TFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
P+G L A LW++ + + T KGHSG+++ + + L + S D +V V
Sbjct: 76 PNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAV 135
Query: 721 WDLHTLAVKTKILEHIAPV-LCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
WD T ++ H + V C A + LV +G DD V + + A + +
Sbjct: 136 WDSETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDDGTVKLWDIRKKAAIQTF-QNTY 194
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQ 838
V +V + I+G D + W++ L T+ + ++ + +LL+
Sbjct: 195 QVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNA 254
Query: 839 GDNELH---LRTFITGTYLHPLKR------HKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
DN + +R F + + K ++C + D S++A G AD+ +Y++
Sbjct: 255 MDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRC-SWSPDGSKIAAGSADRFVYVWD 313
Query: 890 LHSAQLL 896
S ++L
Sbjct: 314 TTSRRIL 320
Score = 54.4 bits (125), Expect = 3e-06
Identities = 53/245 (21%), Positives = 107/245 (43%), Gaps = 13/245 (5%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHI-TCVTFSPNNLLVLSGSEDR 1030
L + DG + S V VW T L GH + +C + LV +GS+D
Sbjct: 115 LHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDDG 174
Query: 1031 TVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG 1090
TV +W + + T++ ++ + + + +S ++ VW + + ++ G
Sbjct: 175 TVKLWDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRG 233
Query: 1091 PSASID-VTLNMK--YAVLSDGDNSVRIWSLAGGDNSEDNRR----SVSHAER--ITCFA 1141
+ S+ ++L+ + Y + + DN+VR+W + E + +V + E+ + C +
Sbjct: 234 HADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRC-S 292
Query: 1142 LTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNL 1201
+ D + GS D + VW ++ L GH+ + VA ++ ++S S D L
Sbjct: 293 WSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFH-PDEPIIISASSDKRL 351
Query: 1202 IVWDI 1206
+ +I
Sbjct: 352 YMGEI 356
Score = 46.0 bits (104), Expect = 0.001
Identities = 39/220 (17%), Positives = 83/220 (37%), Gaps = 4/220 (1%)
Query: 673 AGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKI 732
AG P+ + + + GH G + C L + D +++W+++
Sbjct: 47 AGPPRCSSLQA--PIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYAT 104
Query: 733 LE-HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTS-VKVIQDG 790
L+ H V+ + + S++ S D V + G V +L H V S +
Sbjct: 105 LKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARKSP 164
Query: 791 NIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFIT 850
+ TGS DGTV W++ + T + D + +++ DN++ +
Sbjct: 165 QLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQ 224
Query: 851 GTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ ++ H V ++ + S + D + ++ +
Sbjct: 225 NKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDV 264
Score = 44.4 bits (100), Expect = 0.003
Identities = 61/314 (19%), Positives = 118/314 (37%), Gaps = 23/314 (7%)
Query: 769 ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV----ENFTLLSTVTAGVPIHI 824
A + L H G V K +G+ + D + WNV +N+ L +G + +
Sbjct: 57 APIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKG-HSGAVMEL 115
Query: 825 FDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVK-CFCVAHDSSRVAVGCADQ 883
TD ++ L + D + + TG + LK H + V C+ V G D
Sbjct: 116 HYNTDGSM-LFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDDG 174
Query: 884 RIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAG-GNRVTIYSFHTEDNLTNFRPT 942
+ L+ + ++T +++ G N + ++ ++ LT
Sbjct: 175 TVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLR-QNKLT----- 228
Query: 943 KQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQA 1002
R S T ++L +E S L+ + R + V+++Q + H +
Sbjct: 229 -YTMRGHADSVTGLSL-SSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEK 286
Query: 1003 TLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDG 1062
L + C ++SP+ + +GS DR V VW GH+ +I + D
Sbjct: 287 NL------LRC-SWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDE 339
Query: 1063 RRAMSSDRARNVHV 1076
+S+ + +++
Sbjct: 340 PIIISASSDKRLYM 353
>AF087895-1|AAP97194.1| 375|Homo sapiens G-16 protein.
Length = 375
Score = 87.0 bits (206), Expect = 4e-16
Identities = 38/109 (34%), Positives = 58/109 (53%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+CL++S G LG S G +++WQ S L+ L GH+ + C F P+ L+VLSG
Sbjct: 78 ITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVLSGGM 137
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
D + +W D S +T+KGH I ++ GR +S+ R +W
Sbjct: 138 DAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLW 186
Score = 56.0 bits (129), Expect = 9e-07
Identities = 27/114 (23%), Positives = 54/114 (47%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ SI C+ ++ ++ S D ++ +W ++ + H+ V C + +V+
Sbjct: 74 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVL 133
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
SGG D+ + I S D + V H+G + ++ G ++ S+DGT W+
Sbjct: 134 SGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWD 187
Score = 52.4 bits (120), Expect = 1e-05
Identities = 30/118 (25%), Positives = 49/118 (41%), Gaps = 1/118 (0%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H + ITC +++ V+ S D ++K+W+ G+L +VL GH V C + V
Sbjct: 74 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRF-FPSGLVV 132
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
+SG D L +W + + G VS + D T +W+ R
Sbjct: 133 LSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWDCGR 190
Score = 43.6 bits (98), Expect = 0.005
Identities = 28/111 (25%), Positives = 44/111 (39%), Gaps = 4/111 (3%)
Query: 1095 IDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSM 1154
+D++ V S D +++IW + G E R H + C V++G M
Sbjct: 81 LDISSRGGLGVSSSTDGTMKIWQASNG---ELRRVLEGHVFDVNCCRFFPSGLVVLSGGM 137
Query: 1155 DMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
D LK+W + GH + A+ + VVS S D +WD
Sbjct: 138 DAQLKIWSAEDASCVVTFKGHKGGILDTAI-VDRGRNVVSASRDGTARLWD 187
Score = 37.5 bits (83), Expect = 0.35
Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Query: 662 PSGQHLVLAPSAGDPQL--WHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
PSG LV+ D QL W S V TFKGH G IL + + +++ S D +
Sbjct: 127 PSG--LVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTAR 184
Query: 720 VWD 722
+WD
Sbjct: 185 LWD 187
Score = 37.1 bits (82), Expect = 0.46
Identities = 24/113 (21%), Positives = 43/113 (38%), Gaps = 3/113 (2%)
Query: 1007 HIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAM 1066
H ITC+ S L +S S D T+ +WQ ++ +GH + G +
Sbjct: 74 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVL 133
Query: 1067 SSDRARNVHVWLVDSGIVLHSATGPSASI-DVTL--NMKYAVLSDGDNSVRIW 1116
S + +W + + + G I D + + V + D + R+W
Sbjct: 134 SGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLW 186
>EF011621-1|ABK41111.1| 357|Homo sapiens CDW11/WDR57 protein.
Length = 357
Score = 86.6 bits (205), Expect = 6e-16
Identities = 51/208 (24%), Positives = 98/208 (47%), Gaps = 10/208 (4%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL-ADNSPSLTYKGHSSAIQTLLMMSDG 1062
L+GH G + C F PN + S DR +++W + D T KGHS A+ L +DG
Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121
Query: 1063 RRAMSSDRARNVHVWLVDSGIVLHSATGPSASID----VTLNMKYAVLSDGDNSVRIWSL 1118
S+ + V VW ++G + G ++ ++ + D +V++W +
Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 181
Query: 1119 AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDI 1178
+ ++ + ++ S +++G +D +KVW L KL+ + GH+D
Sbjct: 182 ----RKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADS 237
Query: 1179 VTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
VT +++S + + ++S + D + VWD+
Sbjct: 238 VTGLSLS-SEGSYLLSNAMDNTVRVWDV 264
Score = 68.5 bits (160), Expect = 2e-10
Identities = 61/290 (21%), Positives = 124/290 (42%), Gaps = 14/290 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQL-STHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
+ C + +G AS L+ +W + ATL GH G + + ++ + ++ S S
Sbjct: 69 VYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSAS 128
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAM-SSDRARNVHVWLVDSGIVLH 1086
D+TV VW KGH+S + + G + + + V +W + +
Sbjct: 129 TDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQ 188
Query: 1087 SATGPSASIDVTLN-MKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTA 1144
+ + VT N ++S G DN +++W L + R HA+ +T +L++
Sbjct: 189 TFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMR---GHADSVTGLSLSS 245
Query: 1145 DSQHVVTGSMDMSLKVWKL----DGGKLSQVLVG--HSDIVTCVAVSIT-NKTQVVSGSW 1197
+ ++++ +MD +++VW + + ++ G H+ + S + + +++ +GS
Sbjct: 246 EGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSA 305
Query: 1198 DCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
D + VWD + + V D I +S + DK L + E
Sbjct: 306 DRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGE 355
Score = 64.9 bits (151), Expect = 2e-09
Identities = 40/148 (27%), Positives = 67/148 (45%), Gaps = 2/148 (1%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSI-LCMCVTRESQYLLTGSEDTSVIVWD 722
G L A + +W + +V KGH+ + C R Q + TGS+D +V +WD
Sbjct: 121 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD 180
Query: 723 LHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ A + ++ VL V +ISGG D+ + + L L + H SVT
Sbjct: 181 IRKKAA-IQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVT 239
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVENF 810
+ + +G+ ++ + D TV W+V F
Sbjct: 240 GLSLSSEGSYLLSNAMDNTVRVWDVRPF 267
Score = 56.0 bits (129), Expect = 9e-07
Identities = 43/215 (20%), Positives = 88/215 (40%), Gaps = 12/215 (5%)
Query: 1041 SPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLV----DSGIVLHSATGPSASID 1096
+P + GH + +G S+ R + +W V D+ L +G +
Sbjct: 57 APIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELH 116
Query: 1097 VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI-TCFALTADSQHVVTGSMD 1155
+ + D +V +W + E +R H + +C+ Q V TGS D
Sbjct: 117 YNTDGSMLFSASTDKTVAVWD---SETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDD 173
Query: 1156 MSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKT-QVVSGSWDCNLIVWDINTXXXXXX 1214
++K+W + + + + +AV+ + + Q++SG D ++ VWD+
Sbjct: 174 GTVKLWDI---RKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYT 230
Query: 1215 XXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
VT + ++ +G+ +S A D T+ +W+ +
Sbjct: 231 MRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVR 265
Score = 55.2 bits (127), Expect = 2e-06
Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 8/133 (6%)
Query: 675 DPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE 734
D ++W + N +T +GH+ S+ + ++ E YLL+ + D +V VWD+ A K + ++
Sbjct: 216 DIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVK 275
Query: 735 HI--------APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
+L + + S + +G D V + ++ KL H GS+ V
Sbjct: 276 IFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAF 335
Query: 787 IQDGNIFITGSQD 799
D I I+ S D
Sbjct: 336 HPDEPIIISASSD 348
Score = 53.6 bits (123), Expect = 5e-06
Identities = 56/247 (22%), Positives = 104/247 (42%), Gaps = 14/247 (5%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVH-TFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
P+G L A LW++ + + T KGHSG+++ + + L + S D +V V
Sbjct: 76 PNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAV 135
Query: 721 WDLHTLAVKTKILEHIAPV-LCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
WD T ++ H + V C A LV +G DD V + + A + +
Sbjct: 136 WDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTF-QNTY 194
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQ 838
V +V + I+G D + W++ L T+ + ++ + +LL+
Sbjct: 195 QVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNA 254
Query: 839 GDNELH---LRTFITGTYLHPLKR------HKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
DN + +R F + + K ++C + D S++A G AD+ +Y++
Sbjct: 255 MDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRC-SWSPDGSKIAAGSADRFVYVWD 313
Query: 890 LHSAQLL 896
S ++L
Sbjct: 314 TTSRRIL 320
Score = 53.6 bits (123), Expect = 5e-06
Identities = 53/245 (21%), Positives = 106/245 (43%), Gaps = 13/245 (5%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHI-TCVTFSPNNLLVLSGSEDR 1030
L + DG + S V VW T L GH + +C LV +GS+D
Sbjct: 115 LHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDG 174
Query: 1031 TVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG 1090
TV +W + + T++ ++ + + + +S ++ VW + + ++ G
Sbjct: 175 TVKLWDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRG 233
Query: 1091 PSASID-VTLNMK--YAVLSDGDNSVRIWSLAGGDNSEDNRR----SVSHAER--ITCFA 1141
+ S+ ++L+ + Y + + DN+VR+W + E + +V + E+ + C +
Sbjct: 234 HADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRC-S 292
Query: 1142 LTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNL 1201
+ D + GS D + VW ++ L GH+ + VA ++ ++S S D L
Sbjct: 293 WSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFH-PDEPIIISASSDKRL 351
Query: 1202 IVWDI 1206
+ +I
Sbjct: 352 YMGEI 356
Score = 48.0 bits (109), Expect = 2e-04
Identities = 40/220 (18%), Positives = 84/220 (38%), Gaps = 4/220 (1%)
Query: 673 AGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKI 732
AG P+ + + + GH G + C L + D +++W+++
Sbjct: 47 AGPPRCSSLQA--PIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYAT 104
Query: 733 LE-HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDG- 790
L+ H V+ + + S++ S D V + G V +L H V S + G
Sbjct: 105 LKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGP 164
Query: 791 NIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFIT 850
+ TGS DGTV W++ + T + D + +++ DN++ +
Sbjct: 165 QLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQ 224
Query: 851 GTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ ++ H V ++ + S + D + ++ +
Sbjct: 225 NKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDV 264
Score = 44.4 bits (100), Expect = 0.003
Identities = 61/314 (19%), Positives = 118/314 (37%), Gaps = 23/314 (7%)
Query: 769 ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV----ENFTLLSTVTAGVPIHI 824
A + L H G V K +G+ + D + WNV +N+ L +G + +
Sbjct: 57 APIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKG-HSGAVMEL 115
Query: 825 FDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVK-CFCVAHDSSRVAVGCADQ 883
TD ++ L + D + + TG + LK H + V C+ V G D
Sbjct: 116 HYNTDGSM-LFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDG 174
Query: 884 RIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAG-GNRVTIYSFHTEDNLTNFRPT 942
+ L+ + ++T +++ G N + ++ ++ LT
Sbjct: 175 TVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLR-QNKLT----- 228
Query: 943 KQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQA 1002
R S T ++L +E S L+ + R + V+++Q + H +
Sbjct: 229 -YTMRGHADSVTGLSL-SSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEK 286
Query: 1003 TLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDG 1062
L + C ++SP+ + +GS DR V VW GH+ +I + D
Sbjct: 287 NL------LRC-SWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDE 339
Query: 1063 RRAMSSDRARNVHV 1076
+S+ + +++
Sbjct: 340 PIIISASSDKRLYM 353
>BC001494-1|AAH01494.1| 357|Homo sapiens WD repeat domain 57 (U5
snRNP specific) protein.
Length = 357
Score = 86.6 bits (205), Expect = 6e-16
Identities = 51/208 (24%), Positives = 98/208 (47%), Gaps = 10/208 (4%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL-ADNSPSLTYKGHSSAIQTLLMMSDG 1062
L+GH G + C F PN + S DR +++W + D T KGHS A+ L +DG
Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121
Query: 1063 RRAMSSDRARNVHVWLVDSGIVLHSATGPSASID----VTLNMKYAVLSDGDNSVRIWSL 1118
S+ + V VW ++G + G ++ ++ + D +V++W +
Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 181
Query: 1119 AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDI 1178
+ ++ + ++ S +++G +D +KVW L KL+ + GH+D
Sbjct: 182 ----RKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADS 237
Query: 1179 VTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
VT +++S + + ++S + D + VWD+
Sbjct: 238 VTGLSLS-SEGSYLLSNAMDNTVRVWDV 264
Score = 68.5 bits (160), Expect = 2e-10
Identities = 61/290 (21%), Positives = 124/290 (42%), Gaps = 14/290 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQL-STHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
+ C + +G AS L+ +W + ATL GH G + + ++ + ++ S S
Sbjct: 69 VYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSAS 128
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAM-SSDRARNVHVWLVDSGIVLH 1086
D+TV VW KGH+S + + G + + + V +W + +
Sbjct: 129 TDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQ 188
Query: 1087 SATGPSASIDVTLN-MKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTA 1144
+ + VT N ++S G DN +++W L + R HA+ +T +L++
Sbjct: 189 TFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMR---GHADSVTGLSLSS 245
Query: 1145 DSQHVVTGSMDMSLKVWKL----DGGKLSQVLVG--HSDIVTCVAVSIT-NKTQVVSGSW 1197
+ ++++ +MD +++VW + + ++ G H+ + S + + +++ +GS
Sbjct: 246 EGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSA 305
Query: 1198 DCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
D + VWD + + V D I +S + DK L + E
Sbjct: 306 DRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGE 355
Score = 64.9 bits (151), Expect = 2e-09
Identities = 40/148 (27%), Positives = 67/148 (45%), Gaps = 2/148 (1%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSI-LCMCVTRESQYLLTGSEDTSVIVWD 722
G L A + +W + +V KGH+ + C R Q + TGS+D +V +WD
Sbjct: 121 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD 180
Query: 723 LHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ A + ++ VL V +ISGG D+ + + L L + H SVT
Sbjct: 181 IRKKAA-IQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVT 239
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVENF 810
+ + +G+ ++ + D TV W+V F
Sbjct: 240 GLSLSSEGSYLLSNAMDNTVRVWDVRPF 267
Score = 56.0 bits (129), Expect = 9e-07
Identities = 43/215 (20%), Positives = 88/215 (40%), Gaps = 12/215 (5%)
Query: 1041 SPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLV----DSGIVLHSATGPSASID 1096
+P + GH + +G S+ R + +W V D+ L +G +
Sbjct: 57 APIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELH 116
Query: 1097 VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI-TCFALTADSQHVVTGSMD 1155
+ + D +V +W + E +R H + +C+ Q V TGS D
Sbjct: 117 YNTDGSMLFSASTDKTVAVWD---SETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDD 173
Query: 1156 MSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKT-QVVSGSWDCNLIVWDINTXXXXXX 1214
++K+W + + + + +AV+ + + Q++SG D ++ VWD+
Sbjct: 174 GTVKLWDI---RKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYT 230
Query: 1215 XXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
VT + ++ +G+ +S A D T+ +W+ +
Sbjct: 231 MRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVR 265
Score = 55.2 bits (127), Expect = 2e-06
Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 8/133 (6%)
Query: 675 DPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE 734
D ++W + N +T +GH+ S+ + ++ E YLL+ + D +V VWD+ A K + ++
Sbjct: 216 DIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVK 275
Query: 735 HI--------APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
+L + + S + +G D V + ++ KL H GS+ V
Sbjct: 276 IFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAF 335
Query: 787 IQDGNIFITGSQD 799
D I I+ S D
Sbjct: 336 HPDEPIIISASSD 348
Score = 53.6 bits (123), Expect = 5e-06
Identities = 56/247 (22%), Positives = 104/247 (42%), Gaps = 14/247 (5%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVH-TFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
P+G L A LW++ + + T KGHSG+++ + + L + S D +V V
Sbjct: 76 PNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAV 135
Query: 721 WDLHTLAVKTKILEHIAPV-LCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
WD T ++ H + V C A LV +G DD V + + A + +
Sbjct: 136 WDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTF-QNTY 194
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQ 838
V +V + I+G D + W++ L T+ + ++ + +LL+
Sbjct: 195 QVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNA 254
Query: 839 GDNELH---LRTFITGTYLHPLKR------HKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
DN + +R F + + K ++C + D S++A G AD+ +Y++
Sbjct: 255 MDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRC-SWSPDGSKIAAGSADRFVYVWD 313
Query: 890 LHSAQLL 896
S ++L
Sbjct: 314 TTSRRIL 320
Score = 53.6 bits (123), Expect = 5e-06
Identities = 53/245 (21%), Positives = 106/245 (43%), Gaps = 13/245 (5%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHI-TCVTFSPNNLLVLSGSEDR 1030
L + DG + S V VW T L GH + +C LV +GS+D
Sbjct: 115 LHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDG 174
Query: 1031 TVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG 1090
TV +W + + T++ ++ + + + +S ++ VW + + ++ G
Sbjct: 175 TVKLWDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRG 233
Query: 1091 PSASID-VTLNMK--YAVLSDGDNSVRIWSLAGGDNSEDNRR----SVSHAER--ITCFA 1141
+ S+ ++L+ + Y + + DN+VR+W + E + +V + E+ + C +
Sbjct: 234 HADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRC-S 292
Query: 1142 LTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNL 1201
+ D + GS D + VW ++ L GH+ + VA ++ ++S S D L
Sbjct: 293 WSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFH-PDEPIIISASSDKRL 351
Query: 1202 IVWDI 1206
+ +I
Sbjct: 352 YMGEI 356
Score = 48.0 bits (109), Expect = 2e-04
Identities = 40/220 (18%), Positives = 84/220 (38%), Gaps = 4/220 (1%)
Query: 673 AGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKI 732
AG P+ + + + GH G + C L + D +++W+++
Sbjct: 47 AGPPRCSSLQA--PIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYAT 104
Query: 733 LE-HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDG- 790
L+ H V+ + + S++ S D V + G V +L H V S + G
Sbjct: 105 LKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGP 164
Query: 791 NIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFIT 850
+ TGS DGTV W++ + T + D + +++ DN++ +
Sbjct: 165 QLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQ 224
Query: 851 GTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ ++ H V ++ + S + D + ++ +
Sbjct: 225 NKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDV 264
Score = 44.4 bits (100), Expect = 0.003
Identities = 61/314 (19%), Positives = 118/314 (37%), Gaps = 23/314 (7%)
Query: 769 ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV----ENFTLLSTVTAGVPIHI 824
A + L H G V K +G+ + D + WNV +N+ L +G + +
Sbjct: 57 APIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKG-HSGAVMEL 115
Query: 825 FDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVK-CFCVAHDSSRVAVGCADQ 883
TD ++ L + D + + TG + LK H + V C+ V G D
Sbjct: 116 HYNTDGSM-LFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDG 174
Query: 884 RIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAG-GNRVTIYSFHTEDNLTNFRPT 942
+ L+ + ++T +++ G N + ++ ++ LT
Sbjct: 175 TVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLR-QNKLT----- 228
Query: 943 KQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQA 1002
R S T ++L +E S L+ + R + V+++Q + H +
Sbjct: 229 -YTMRGHADSVTGLSL-SSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEK 286
Query: 1003 TLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDG 1062
L + C ++SP+ + +GS DR V VW GH+ +I + D
Sbjct: 287 NL------LRC-SWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDE 339
Query: 1063 RRAMSSDRARNVHV 1076
+S+ + +++
Sbjct: 340 PIIISASSDKRLYM 353
>AL451070-1|CAH71848.1| 357|Homo sapiens WD repeat domain 57 (U5
snRNP specific) protein.
Length = 357
Score = 86.6 bits (205), Expect = 6e-16
Identities = 51/208 (24%), Positives = 98/208 (47%), Gaps = 10/208 (4%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL-ADNSPSLTYKGHSSAIQTLLMMSDG 1062
L+GH G + C F PN + S DR +++W + D T KGHS A+ L +DG
Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121
Query: 1063 RRAMSSDRARNVHVWLVDSGIVLHSATGPSASID----VTLNMKYAVLSDGDNSVRIWSL 1118
S+ + V VW ++G + G ++ ++ + D +V++W +
Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 181
Query: 1119 AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDI 1178
+ ++ + ++ S +++G +D +KVW L KL+ + GH+D
Sbjct: 182 ----RKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADS 237
Query: 1179 VTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
VT +++S + + ++S + D + VWD+
Sbjct: 238 VTGLSLS-SEGSYLLSNAMDNTVRVWDV 264
Score = 68.5 bits (160), Expect = 2e-10
Identities = 61/290 (21%), Positives = 124/290 (42%), Gaps = 14/290 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQL-STHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
+ C + +G AS L+ +W + ATL GH G + + ++ + ++ S S
Sbjct: 69 VYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSAS 128
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAM-SSDRARNVHVWLVDSGIVLH 1086
D+TV VW KGH+S + + G + + + V +W + +
Sbjct: 129 TDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQ 188
Query: 1087 SATGPSASIDVTLN-MKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTA 1144
+ + VT N ++S G DN +++W L + R HA+ +T +L++
Sbjct: 189 TFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMR---GHADSVTGLSLSS 245
Query: 1145 DSQHVVTGSMDMSLKVWKL----DGGKLSQVLVG--HSDIVTCVAVSIT-NKTQVVSGSW 1197
+ ++++ +MD +++VW + + ++ G H+ + S + + +++ +GS
Sbjct: 246 EGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSA 305
Query: 1198 DCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
D + VWD + + V D I +S + DK L + E
Sbjct: 306 DRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGE 355
Score = 64.9 bits (151), Expect = 2e-09
Identities = 40/148 (27%), Positives = 67/148 (45%), Gaps = 2/148 (1%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSI-LCMCVTRESQYLLTGSEDTSVIVWD 722
G L A + +W + +V KGH+ + C R Q + TGS+D +V +WD
Sbjct: 121 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD 180
Query: 723 LHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ A + ++ VL V +ISGG D+ + + L L + H SVT
Sbjct: 181 IRKKAA-IQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVT 239
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVENF 810
+ + +G+ ++ + D TV W+V F
Sbjct: 240 GLSLSSEGSYLLSNAMDNTVRVWDVRPF 267
Score = 56.0 bits (129), Expect = 9e-07
Identities = 43/215 (20%), Positives = 88/215 (40%), Gaps = 12/215 (5%)
Query: 1041 SPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLV----DSGIVLHSATGPSASID 1096
+P + GH + +G S+ R + +W V D+ L +G +
Sbjct: 57 APIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELH 116
Query: 1097 VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI-TCFALTADSQHVVTGSMD 1155
+ + D +V +W + E +R H + +C+ Q V TGS D
Sbjct: 117 YNTDGSMLFSASTDKTVAVWD---SETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDD 173
Query: 1156 MSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKT-QVVSGSWDCNLIVWDINTXXXXXX 1214
++K+W + + + + +AV+ + + Q++SG D ++ VWD+
Sbjct: 174 GTVKLWDI---RKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYT 230
Query: 1215 XXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
VT + ++ +G+ +S A D T+ +W+ +
Sbjct: 231 MRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVR 265
Score = 55.2 bits (127), Expect = 2e-06
Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 8/133 (6%)
Query: 675 DPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE 734
D ++W + N +T +GH+ S+ + ++ E YLL+ + D +V VWD+ A K + ++
Sbjct: 216 DIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVK 275
Query: 735 HI--------APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
+L + + S + +G D V + ++ KL H GS+ V
Sbjct: 276 IFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAF 335
Query: 787 IQDGNIFITGSQD 799
D I I+ S D
Sbjct: 336 HPDEPIIISASSD 348
Score = 53.6 bits (123), Expect = 5e-06
Identities = 56/247 (22%), Positives = 104/247 (42%), Gaps = 14/247 (5%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVH-TFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
P+G L A LW++ + + T KGHSG+++ + + L + S D +V V
Sbjct: 76 PNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAV 135
Query: 721 WDLHTLAVKTKILEHIAPV-LCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
WD T ++ H + V C A LV +G DD V + + A + +
Sbjct: 136 WDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTF-QNTY 194
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQ 838
V +V + I+G D + W++ L T+ + ++ + +LL+
Sbjct: 195 QVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNA 254
Query: 839 GDNELH---LRTFITGTYLHPLKR------HKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
DN + +R F + + K ++C + D S++A G AD+ +Y++
Sbjct: 255 MDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRC-SWSPDGSKIAAGSADRFVYVWD 313
Query: 890 LHSAQLL 896
S ++L
Sbjct: 314 TTSRRIL 320
Score = 53.6 bits (123), Expect = 5e-06
Identities = 53/245 (21%), Positives = 106/245 (43%), Gaps = 13/245 (5%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHI-TCVTFSPNNLLVLSGSEDR 1030
L + DG + S V VW T L GH + +C LV +GS+D
Sbjct: 115 LHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDG 174
Query: 1031 TVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG 1090
TV +W + + T++ ++ + + + +S ++ VW + + ++ G
Sbjct: 175 TVKLWDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRG 233
Query: 1091 PSASID-VTLNMK--YAVLSDGDNSVRIWSLAGGDNSEDNRR----SVSHAER--ITCFA 1141
+ S+ ++L+ + Y + + DN+VR+W + E + +V + E+ + C +
Sbjct: 234 HADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRC-S 292
Query: 1142 LTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNL 1201
+ D + GS D + VW ++ L GH+ + VA ++ ++S S D L
Sbjct: 293 WSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFH-PDEPIIISASSDKRL 351
Query: 1202 IVWDI 1206
+ +I
Sbjct: 352 YMGEI 356
Score = 48.0 bits (109), Expect = 2e-04
Identities = 40/220 (18%), Positives = 84/220 (38%), Gaps = 4/220 (1%)
Query: 673 AGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKI 732
AG P+ + + + GH G + C L + D +++W+++
Sbjct: 47 AGPPRCSSLQA--PIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYAT 104
Query: 733 LE-HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDG- 790
L+ H V+ + + S++ S D V + G V +L H V S + G
Sbjct: 105 LKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGP 164
Query: 791 NIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFIT 850
+ TGS DGTV W++ + T + D + +++ DN++ +
Sbjct: 165 QLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQ 224
Query: 851 GTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ ++ H V ++ + S + D + ++ +
Sbjct: 225 NKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDV 264
Score = 44.4 bits (100), Expect = 0.003
Identities = 61/314 (19%), Positives = 118/314 (37%), Gaps = 23/314 (7%)
Query: 769 ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV----ENFTLLSTVTAGVPIHI 824
A + L H G V K +G+ + D + WNV +N+ L +G + +
Sbjct: 57 APIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKG-HSGAVMEL 115
Query: 825 FDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVK-CFCVAHDSSRVAVGCADQ 883
TD ++ L + D + + TG + LK H + V C+ V G D
Sbjct: 116 HYNTDGSM-LFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDG 174
Query: 884 RIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAG-GNRVTIYSFHTEDNLTNFRPT 942
+ L+ + ++T +++ G N + ++ ++ LT
Sbjct: 175 TVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLR-QNKLT----- 228
Query: 943 KQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQA 1002
R S T ++L +E S L+ + R + V+++Q + H +
Sbjct: 229 -YTMRGHADSVTGLSL-SSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEK 286
Query: 1003 TLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDG 1062
L + C ++SP+ + +GS DR V VW GH+ +I + D
Sbjct: 287 NL------LRC-SWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDE 339
Query: 1063 RRAMSSDRARNVHV 1076
+S+ + +++
Sbjct: 340 PIIISASSDKRLYM 353
>AF083383-1|AAC64084.1| 310|Homo sapiens 38kDa splicing factor
protein.
Length = 310
Score = 86.6 bits (205), Expect = 6e-16
Identities = 51/208 (24%), Positives = 98/208 (47%), Gaps = 10/208 (4%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL-ADNSPSLTYKGHSSAIQTLLMMSDG 1062
L+GH G + C F PN + S DR +++W + D T KGHS A+ L +DG
Sbjct: 3 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 62
Query: 1063 RRAMSSDRARNVHVWLVDSGIVLHSATGPSASID----VTLNMKYAVLSDGDNSVRIWSL 1118
S+ + V VW ++G + G ++ ++ + D +V++W +
Sbjct: 63 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 122
Query: 1119 AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDI 1178
+ ++ + ++ S +++G +D +KVW L KL+ + GH+D
Sbjct: 123 ----RKKAAVQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADS 178
Query: 1179 VTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
VT +++S + + ++S + D + VWD+
Sbjct: 179 VTGLSLS-SEGSYLLSNAMDNTVRVWDV 205
Score = 65.3 bits (152), Expect = 2e-09
Identities = 40/148 (27%), Positives = 67/148 (45%), Gaps = 2/148 (1%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSI-LCMCVTRESQYLLTGSEDTSVIVWD 722
G L A + +W + +V KGH+ + C R Q + TGS+D +V +WD
Sbjct: 62 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD 121
Query: 723 LHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ A + ++ VL V +ISGG D+ + + L L + H SVT
Sbjct: 122 IRKKAA-VQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVT 180
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVENF 810
+ + +G+ ++ + D TV W+V F
Sbjct: 181 GLSLSSEGSYLLSNAMDNTVRVWDVRPF 208
Score = 63.7 bits (148), Expect = 5e-09
Identities = 44/197 (22%), Positives = 89/197 (45%), Gaps = 7/197 (3%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQL-STHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
+ C + +G AS L+ +W + ATL GH G + + ++ + ++ S S
Sbjct: 10 VYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSAS 69
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAM-SSDRARNVHVWLVDSGIVLH 1086
D+TV VW KGH+S + + G + + + V +W + +
Sbjct: 70 TDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAVQ 129
Query: 1087 SATGPSASIDVTLN-MKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTA 1144
+ + VT N ++S G DN +++W L + R HA+ +T +L++
Sbjct: 130 TFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMR---GHADSVTGLSLSS 186
Query: 1145 DSQHVVTGSMDMSLKVW 1161
+ ++++ +MD +++VW
Sbjct: 187 EGSYLLSNAMDNTVRVW 203
Score = 53.2 bits (122), Expect = 7e-06
Identities = 43/207 (20%), Positives = 83/207 (40%), Gaps = 10/207 (4%)
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLV----DSGIVLHSATGPSASIDVTLNMKY 1103
GH + +G S+ R + +W V D+ L +G + +
Sbjct: 5 GHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSM 64
Query: 1104 AVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI-TCFALTADSQHVVTGSMDMSLKVWK 1162
+ D +V +W + E +R H + +C+ Q V TGS D ++K+W
Sbjct: 65 LFSASTDKTVAVWD---SETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD 121
Query: 1163 LDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKV 1222
+ Q ++ V + T+ Q++SG D ++ VWD+ V
Sbjct: 122 IRKKAAVQTFQNTYQVLA-VTFNDTSD-QIISGGIDNDIKVWDLRQNKLTYTMRGHADSV 179
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWETK 1249
T + ++ +G+ +S A D T+ +W+ +
Sbjct: 180 TGLSLSSEGSYLLSNAMDNTVRVWDVR 206
Score = 51.6 bits (118), Expect = 2e-05
Identities = 56/243 (23%), Positives = 101/243 (41%), Gaps = 14/243 (5%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVH-TFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
P+G L A LW++ + + T KGHSG+++ + + L + S D +V V
Sbjct: 17 PNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAV 76
Query: 721 WDLHTLAVKTKILEHIAPV-LCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
WD T ++ H + V C A LV +G DD V + + A V +
Sbjct: 77 WDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAVQTF-QNTY 135
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQ 838
V +V + I+G D + W++ L T+ + ++ + +LL+
Sbjct: 136 QVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNA 195
Query: 839 GDNELH---LRTFITGTYLHPLKR------HKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
DN + +R F + + K ++C + D S++A G AD+ +Y++
Sbjct: 196 MDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRC-SWSPDGSKIAAGSADRFVYVWD 254
Query: 890 LHS 892
S
Sbjct: 255 TTS 257
Score = 47.2 bits (107), Expect = 4e-04
Identities = 37/201 (18%), Positives = 77/201 (38%), Gaps = 2/201 (0%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE-HIAPVLCVAAIVNRSL 750
GH G + C L + D +++W+++ L+ H V+ + + S+
Sbjct: 5 GHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSM 64
Query: 751 VISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDG-NIFITGSQDGTVCTWNVEN 809
+ S D V + G V +L H V S + G + TGS DGTV W++
Sbjct: 65 LFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRK 124
Query: 810 FTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCV 869
+ T + D + +++ DN++ + + ++ H V +
Sbjct: 125 KAAVQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSL 184
Query: 870 AHDSSRVAVGCADQRIYLYSL 890
+ + S + D + ++ +
Sbjct: 185 SSEGSYLLSNAMDNTVRVWDV 205
Score = 41.9 bits (94), Expect = 0.016
Identities = 27/96 (28%), Positives = 46/96 (47%), Gaps = 8/96 (8%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPS----LT 1045
++VW L ++L T+ GH +T ++ S +LS + D TV VW + +P
Sbjct: 158 IKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKI 217
Query: 1046 YKGHSSAIQ-TLLMMS---DGRRAMSSDRARNVHVW 1077
++G+ + LL S DG + + R V+VW
Sbjct: 218 FQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVW 253
Score = 38.7 bits (86), Expect = 0.15
Identities = 55/268 (20%), Positives = 102/268 (38%), Gaps = 23/268 (8%)
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV----ENFTLLSTVTAGVPIHIFDVTD 829
L H G V K +G+ + D + WNV +N+ L +G + + TD
Sbjct: 3 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKG-HSGAVMELHYNTD 61
Query: 830 DNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKV-KCFCVAHDSSRVAVGCADQRIYLY 888
++ L + D + + TG + LK H + V C+ V G D + L+
Sbjct: 62 GSM-LFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLW 120
Query: 889 SLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAG-GNRVTIYSFHTEDNLTNFRPTKQMKR 947
+ ++T +++ G N + ++ ++ LT R
Sbjct: 121 DIRKKAAVQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLR-QNKLT------YTMR 173
Query: 948 RQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGH 1007
S T ++ L +E S L+ + R + V+++Q + H + L
Sbjct: 174 GHADSVTGLS-LSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNL--- 229
Query: 1008 IGHITCVTFSPNNLLVLSGSEDRTVVVW 1035
+ C ++SP+ + +GS DR V VW
Sbjct: 230 ---LRC-SWSPDGSKIAAGSADRFVYVW 253
>U82756-1|AAC02261.1| 520|Homo sapiens WD splicing factor Hprp4p
protein.
Length = 520
Score = 86.2 bits (204), Expect = 8e-16
Identities = 71/316 (22%), Positives = 132/316 (41%), Gaps = 15/316 (4%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T QM+ KS ++ ++ D PIS S + ++ A+ C GL ++W + L
Sbjct: 206 TSQMQELH-KSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLL 264
Query: 1002 ATLNGH------IGHI--TCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
TL GH + I + V+ P ++ + S + D +V +W L + P +GH+ +
Sbjct: 265 HTLRGHNTKKEQLHSIPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRV 324
Query: 1054 QTLLMMSDGRRAMSSDRARNVHVW-LVDSGIVLHSATGPSASIDVTLNMKYAVLSDG--D 1110
++ GR ++ R+ +W L +LH D+ + ++ G D
Sbjct: 325 ARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLD 384
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
R+W L G H + I + + H+ TGS D + KVW L +
Sbjct: 385 AFGRVWDLRTG---RCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 441
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
+ H ++VT V + +++G++D +W KV + ++ D
Sbjct: 442 TIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSD 501
Query: 1231 GTIAVSCAEDKTLIIW 1246
G + +C+ D+T +W
Sbjct: 502 GQLIATCSYDRTFKLW 517
Score = 57.2 bits (132), Expect = 4e-07
Identities = 56/234 (23%), Positives = 93/234 (39%), Gaps = 4/234 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ L P +L + G +LW + S+ V +GH+ + + ++L T D S
Sbjct: 285 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRS 344
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+WDL H V +A + SL +GG D+ + L G + L+ H
Sbjct: 345 WRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGH 404
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHI---FDVTDDNVFL 834
+ + +G TGS D T W++ + T+ A + F+ N FL
Sbjct: 405 LKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGN-FL 463
Query: 835 LTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
LT DN + T + L L H+ KV ++ D +A D+ L+
Sbjct: 464 LTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 517
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSP-NNLLVLSGSEDR 1030
+ S +G A+G +VW L R T+ H +T V F P + +L+G+ D
Sbjct: 411 INFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDN 470
Query: 1031 TVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
T +W SP T GH + L + SDG+ + R +W+ +
Sbjct: 471 TAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE 520
Score = 43.2 bits (97), Expect = 0.007
Identities = 31/133 (23%), Positives = 55/133 (41%), Gaps = 1/133 (0%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + + + +GH I + + ++ TGS D + VWDL I H
Sbjct: 388 RVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQ 447
Query: 737 APVLCVA-AIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFIT 795
V V ++ + +++G D+ I + + + L H G V + + DG + T
Sbjct: 448 NLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIAT 507
Query: 796 GSQDGTVCTWNVE 808
S D T W E
Sbjct: 508 CSYDRTFKLWMAE 520
Score = 35.9 bits (79), Expect = 1.1
Identities = 38/180 (21%), Positives = 72/180 (40%), Gaps = 6/180 (3%)
Query: 1085 LHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTA 1144
LHS + S+D ++ A + D SV++WSL D+ E H R+
Sbjct: 277 LHSIPKSTVSLDPK-DVNLASCA-ADGSVKLWSL---DSDEPVADIEGHTVRVARVMWHP 331
Query: 1145 DSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
+ + T D S ++W L+ + GHS V +A + + +G D VW
Sbjct: 332 SGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFH-QDGSLAGTGGLDAFGRVW 390
Query: 1205 DINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLL 1264
D+ T ++ + + +G + + D T +W+ ++ + + H L+
Sbjct: 391 DLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLV 450
>BC024267-1|AAH24267.1| 594|Homo sapiens TRAF7 protein protein.
Length = 594
Score = 85.4 bits (202), Expect = 1e-15
Identities = 70/283 (24%), Positives = 128/283 (45%), Gaps = 16/283 (5%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQL-STHRLQATLNGHIGHITCVTFSPNNLLVLSG 1026
P+ CL V G L SG + ++VW +T++ Q TL GH G + + L SG
Sbjct: 322 PVWCLCVYSMGDLLFSGSSDKTIKVWDTCTTYKCQKTLEGHDGIVLALCIQGCKLY--SG 379
Query: 1027 SEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW-LVDSGIVL 1085
S D T++VW + + T + H + + TL+ + S + + VW +V + + L
Sbjct: 380 SADCTIIVWDIQNLQKVNTIRAHDNPVCTLV---SSHNVLFSGSLKAIKVWDIVGTELKL 436
Query: 1086 HSA-TGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTA 1144
TG + + + + + S +++IW + D V + +++
Sbjct: 437 KKELTGLNHWVRALVAAQSYLYSGSYQTIKIWDIRTLDCIH-----VLQTSGGSVYSIAV 491
Query: 1145 DSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAV-SITNKTQVVSGSWDCNLIV 1203
+ H+V G+ + + VW ++ + + L GH V +AV S ++T+V S S+D +L V
Sbjct: 492 TNHHIVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVISTPDQTKVFSASYDRSLRV 551
Query: 1204 WDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
W ++ VT + V+ G + S A D T+ +W
Sbjct: 552 WSMDNMICTQTLLRHQGSVTALAVS-RGRL-FSGAVDSTVKVW 592
Score = 59.3 bits (137), Expect = 1e-07
Identities = 53/252 (21%), Positives = 107/252 (42%), Gaps = 14/252 (5%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN-SPSLTYKGHSSAIQTLL 1057
+ + T GH G + C+ L+ SGS D+T+ VW T +GH + L
Sbjct: 311 KCKGTFVGHQGPVWCLCVYSMGDLLFSGSSDKTIKVWDTCTTYKCQKTLEGHDGIV--LA 368
Query: 1058 MMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
+ G + S + VW + + +++ + ++ + S ++++W
Sbjct: 369 LCIQGCKLYSGSADCTIIVWDIQNLQKVNTIRAHDNPVCTLVSSHNVLFSGSLKAIKVWD 428
Query: 1118 LAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHS 1176
+ G + + ++H R AL A ++ +GS ++K+W D L + V +
Sbjct: 429 IVGTELKLKKELTGLNHWVR----ALVAAQSYLYSGSY-QTIKIW--DIRTLDCIHVLQT 481
Query: 1177 DIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV--TGDGTIA 1234
+ ++++TN +V G+++ + VWDI + V + V T D T
Sbjct: 482 SGGSVYSIAVTNH-HIVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVISTPDQTKV 540
Query: 1235 VSCAEDKTLIIW 1246
S + D++L +W
Sbjct: 541 FSASYDRSLRVW 552
Score = 52.4 bits (120), Expect = 1e-05
Identities = 33/131 (25%), Positives = 67/131 (51%), Gaps = 6/131 (4%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W I + +H + GS+ + VT + +++ G+ + + VWD+ + + H+
Sbjct: 466 KIWDIRTLDCIHVLQTSGGSVYSIAVT--NHHIVCGTYENLIHVWDIESKEQVRTLTGHV 523
Query: 737 APVLCVAAIV--NRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
V +A I +++ V S D ++ + S+ + L H+GSVT++ V + G +F
Sbjct: 524 GTVYALAVISTPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSVTALAVSR-GRLF- 581
Query: 795 TGSQDGTVCTW 805
+G+ D TV W
Sbjct: 582 SGAVDSTVKVW 592
Score = 50.4 bits (115), Expect = 5e-05
Identities = 34/120 (28%), Positives = 54/120 (45%), Gaps = 6/120 (5%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE-HIAPVLCVAAIVN 747
TF GH G + C+CV L +GS D ++ VWD T K LE H VL A +
Sbjct: 315 TFVGHQGPVWCLCVYSMGDLLFSGSSDKTIKVWDTCTTYKCQKTLEGHDGIVL--ALCIQ 372
Query: 748 RSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
+ SG D +I+ + + V + H V + ++ N+ +GS + W++
Sbjct: 373 GCKLYSGSADCTIIVWDIQNLQKVNTIRAHDNPVCT--LVSSHNVLFSGSLK-AIKVWDI 429
Score = 47.6 bits (108), Expect = 3e-04
Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 4/103 (3%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCV--TRESQYLLTGSEDTS 717
+A + H+V +W I S +V T GH G++ + V T + + + S D S
Sbjct: 489 IAVTNHHIVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVISTPDQTKVFSASYDRS 548
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAV 760
+ VW + + +L H V +A V+R + SG DS V
Sbjct: 549 LRVWSMDNMICTQTLLRHQGSVTALA--VSRGRLFSGAVDSTV 589
Score = 37.1 bits (82), Expect = 0.46
Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 729 KTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTK-LDHHRGSVTSVKVI 787
K + H PV C+ L+ SG D + + K L+ H G V ++ I
Sbjct: 313 KGTFVGHQGPVWCLCVYSMGDLLFSGSSDKTIKVWDTCTTYKCQKTLEGHDGIVLAL-CI 371
Query: 788 QDGNIFITGSQDGTVCTWNVENFTLLSTVTA 818
Q ++ +GS D T+ W+++N ++T+ A
Sbjct: 372 QGCKLY-SGSADCTIIVWDIQNLQKVNTIRA 401
>AY569455-1|AAS68363.1| 670|Homo sapiens TRAF7 protein.
Length = 670
Score = 85.4 bits (202), Expect = 1e-15
Identities = 70/283 (24%), Positives = 128/283 (45%), Gaps = 16/283 (5%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQL-STHRLQATLNGHIGHITCVTFSPNNLLVLSG 1026
P+ CL V G L SG + ++VW +T++ Q TL GH G + + L SG
Sbjct: 398 PVWCLCVYSMGDLLFSGSSDKTIKVWDTCTTYKCQKTLEGHDGIVLALCIQGCKLY--SG 455
Query: 1027 SEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW-LVDSGIVL 1085
S D T++VW + + T + H + + TL+ + S + + VW +V + + L
Sbjct: 456 SADCTIIVWDIQNLQKVNTIRAHDNPVCTLV---SSHNVLFSGSLKAIKVWDIVGTELKL 512
Query: 1086 HSA-TGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTA 1144
TG + + + + + S +++IW + D V + +++
Sbjct: 513 KKELTGLNHWVRALVAAQSYLYSGSYQTIKIWDIRTLDCIH-----VLQTSGGSVYSIAV 567
Query: 1145 DSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAV-SITNKTQVVSGSWDCNLIV 1203
+ H+V G+ + + VW ++ + + L GH V +AV S ++T+V S S+D +L V
Sbjct: 568 TNHHIVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVISTPDQTKVFSASYDRSLRV 627
Query: 1204 WDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
W ++ VT + V+ G + S A D T+ +W
Sbjct: 628 WSMDNMICTQTLLRHQGSVTALAVS-RGRL-FSGAVDSTVKVW 668
Score = 59.3 bits (137), Expect = 1e-07
Identities = 53/252 (21%), Positives = 107/252 (42%), Gaps = 14/252 (5%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN-SPSLTYKGHSSAIQTLL 1057
+ + T GH G + C+ L+ SGS D+T+ VW T +GH + L
Sbjct: 387 KCKGTFVGHQGPVWCLCVYSMGDLLFSGSSDKTIKVWDTCTTYKCQKTLEGHDGIV--LA 444
Query: 1058 MMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
+ G + S + VW + + +++ + ++ + S ++++W
Sbjct: 445 LCIQGCKLYSGSADCTIIVWDIQNLQKVNTIRAHDNPVCTLVSSHNVLFSGSLKAIKVWD 504
Query: 1118 LAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHS 1176
+ G + + ++H R AL A ++ +GS ++K+W D L + V +
Sbjct: 505 IVGTELKLKKELTGLNHWVR----ALVAAQSYLYSGSY-QTIKIW--DIRTLDCIHVLQT 557
Query: 1177 DIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV--TGDGTIA 1234
+ ++++TN +V G+++ + VWDI + V + V T D T
Sbjct: 558 SGGSVYSIAVTNH-HIVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVISTPDQTKV 616
Query: 1235 VSCAEDKTLIIW 1246
S + D++L +W
Sbjct: 617 FSASYDRSLRVW 628
Score = 52.4 bits (120), Expect = 1e-05
Identities = 33/131 (25%), Positives = 67/131 (51%), Gaps = 6/131 (4%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W I + +H + GS+ + VT + +++ G+ + + VWD+ + + H+
Sbjct: 542 KIWDIRTLDCIHVLQTSGGSVYSIAVT--NHHIVCGTYENLIHVWDIESKEQVRTLTGHV 599
Query: 737 APVLCVAAIV--NRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
V +A I +++ V S D ++ + S+ + L H+GSVT++ V + G +F
Sbjct: 600 GTVYALAVISTPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSVTALAVSR-GRLF- 657
Query: 795 TGSQDGTVCTW 805
+G+ D TV W
Sbjct: 658 SGAVDSTVKVW 668
Score = 50.4 bits (115), Expect = 5e-05
Identities = 34/120 (28%), Positives = 54/120 (45%), Gaps = 6/120 (5%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE-HIAPVLCVAAIVN 747
TF GH G + C+CV L +GS D ++ VWD T K LE H VL A +
Sbjct: 391 TFVGHQGPVWCLCVYSMGDLLFSGSSDKTIKVWDTCTTYKCQKTLEGHDGIVL--ALCIQ 448
Query: 748 RSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
+ SG D +I+ + + V + H V + ++ N+ +GS + W++
Sbjct: 449 GCKLYSGSADCTIIVWDIQNLQKVNTIRAHDNPVCT--LVSSHNVLFSGSLK-AIKVWDI 505
Score = 47.6 bits (108), Expect = 3e-04
Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 4/103 (3%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCV--TRESQYLLTGSEDTS 717
+A + H+V +W I S +V T GH G++ + V T + + + S D S
Sbjct: 565 IAVTNHHIVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVISTPDQTKVFSASYDRS 624
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAV 760
+ VW + + +L H V +A V+R + SG DS V
Sbjct: 625 LRVWSMDNMICTQTLLRHQGSVTALA--VSRGRLFSGAVDSTV 665
Score = 37.1 bits (82), Expect = 0.46
Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 729 KTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTK-LDHHRGSVTSVKVI 787
K + H PV C+ L+ SG D + + K L+ H G V ++ I
Sbjct: 389 KGTFVGHQGPVWCLCVYSMGDLLFSGSSDKTIKVWDTCTTYKCQKTLEGHDGIVLAL-CI 447
Query: 788 QDGNIFITGSQDGTVCTWNVENFTLLSTVTA 818
Q ++ +GS D T+ W+++N ++T+ A
Sbjct: 448 QGCKLY-SGSADCTIIVWDIQNLQKVNTIRA 477
>AF001687-1|AAB87640.1| 521|Homo sapiens U4/U6 snRNP 60 kDa protein
protein.
Length = 521
Score = 85.0 bits (201), Expect = 2e-15
Identities = 70/316 (22%), Positives = 130/316 (41%), Gaps = 15/316 (4%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T QM+ KS ++ ++ D PIS S + ++ A+ C GL ++W + L
Sbjct: 207 TSQMQELH-KSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLL 265
Query: 1002 ATLNGHIGHITCVTFSPNNLLVL--------SGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
TL GH ++ + F P + + L S + D +V +W L + P +GH+ +
Sbjct: 266 HTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRV 325
Query: 1054 QTLLMMSDGRRAMSSDRARNVHVW-LVDSGIVLHSATGPSASIDVTLNMKYAVLSDG--D 1110
++ GR ++ R+ +W L +LH D+ + ++ G D
Sbjct: 326 ARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLD 385
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
R+W L G H + I + + H+ TGS D + KVW L +
Sbjct: 386 AFGRVWDLRTG---RCIMFLEDHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 442
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGD 1230
+ H ++VT V + +++G++D +W KV + ++ D
Sbjct: 443 TIPPHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSD 502
Query: 1231 GTIAVSCAEDKTLIIW 1246
G + + + D+T +W
Sbjct: 503 GQLIATYSYDRTFKLW 518
Score = 56.8 bits (131), Expect = 5e-07
Identities = 56/236 (23%), Positives = 93/236 (39%), Gaps = 4/236 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ L P +L + G +LW + S+ V +GH+ + + ++L T D S
Sbjct: 286 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRS 345
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+WDL H V +A + SL +GG D+ + L G + L+ H
Sbjct: 346 WRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEDH 405
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHI---FDVTDDNVFL 834
+ + +G TGS D T W++ + T+ + F+ N FL
Sbjct: 406 LKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPPHQNLVTGVKFEPIHGN-FL 464
Query: 835 LTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
LT DN + T + L L H+ KV ++ D +A D+ L+ L
Sbjct: 465 LTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATYSYDRTFKLWML 520
Score = 50.8 bits (116), Expect = 4e-05
Identities = 30/110 (27%), Positives = 49/110 (44%), Gaps = 1/110 (0%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSP-NNLLVLSGSEDR 1030
+ S +G A+G +VW L R T+ H +T V F P + +L+G+ D
Sbjct: 412 INFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPPHQNLVTGVKFEPIHGNFLLTGAYDN 471
Query: 1031 TVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
T +W SP T GH + L + SDG+ + R +W+++
Sbjct: 472 TAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATYSYDRTFKLWMLE 521
Score = 40.7 bits (91), Expect = 0.038
Identities = 30/133 (22%), Positives = 55/133 (41%), Gaps = 1/133 (0%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + + + + H I + + ++ TGS D + VWDL I H
Sbjct: 389 RVWDLRTGRCIMFLEDHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPPHQ 448
Query: 737 APVLCVA-AIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFIT 795
V V ++ + +++G D+ I + + + L H G V + + DG + T
Sbjct: 449 NLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIAT 508
Query: 796 GSQDGTVCTWNVE 808
S D T W +E
Sbjct: 509 YSYDRTFKLWMLE 521
Score = 33.9 bits (74), Expect = 4.3
Identities = 32/179 (17%), Positives = 65/179 (36%), Gaps = 9/179 (5%)
Query: 991 RVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
R+W L GH + + F + L +G D VW L + + H
Sbjct: 347 RLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEDHL 406
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMK-----YAV 1105
I + +G + VW + +++ P ++ + + + +
Sbjct: 407 KEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIP-PHQNLVTGVKFEPIHGNFLL 465
Query: 1106 LSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLD 1164
DN+ +IW+ G + H ++ +++D Q + T S D + K+W L+
Sbjct: 466 TGAYDNTAKIWTHPGWSPL---KTLAGHEGKVMGLDISSDGQLIATYSYDRTFKLWMLE 521
>BC119693-1|AAI19694.1| 441|Homo sapiens WDR51A protein protein.
Length = 441
Score = 84.6 bits (200), Expect = 2e-15
Identities = 61/265 (23%), Positives = 108/265 (40%), Gaps = 11/265 (4%)
Query: 1000 LQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
L+ GH +TCV FS N + SGS D ++VW + S + + GH A+ +
Sbjct: 45 LERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFS 104
Query: 1060 SDGRRAMSSDRARNVHVWLVD---SGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIW 1116
G S R + V +W+ + V + T S+ + + V + D +V++W
Sbjct: 105 PSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 164
Query: 1117 SLAGGDNSEDNRRSVS-HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGH 1175
+ + + S+S H + C + D + +V+ S D ++K+W + H
Sbjct: 165 AT----HRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEH 220
Query: 1176 SDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAV 1235
VT V + T + + D + VWD+ T V + G +
Sbjct: 221 GGFVTYVDFHPSG-TCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLI 279
Query: 1236 SCAEDKTLIIWETKRGLALTSFSLH 1260
+ + D TL I + G L ++LH
Sbjct: 280 TASSDSTLKILDLMEGRLL--YTLH 302
Score = 82.6 bits (195), Expect = 9e-15
Identities = 60/283 (21%), Positives = 118/283 (41%), Gaps = 7/283 (2%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
++C++ S + + ASG + VW + GH +TCV FSP+ L+ SGS
Sbjct: 56 VTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSR 115
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D+TV +W S ++ H++ ++++ SDG+ +++ + V VW L S
Sbjct: 116 DKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSL 175
Query: 1089 TGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
+ + + + + V + D +V++W + + E H +T
Sbjct: 176 SQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKS---SRECVHSYCEHGGFVTYVDFHPS 232
Query: 1146 SQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ MD ++KVW + +L Q HS V ++ + +++ S D L + D
Sbjct: 233 GTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFH-PSGNYLITASSDSTLKILD 291
Query: 1206 INTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWET 1248
+ T V + G S D+ +++W++
Sbjct: 292 LMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 334
Score = 72.9 bits (171), Expect = 8e-12
Identities = 44/154 (28%), Positives = 67/154 (43%), Gaps = 1/154 (0%)
Query: 1128 RRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSIT 1187
R H + +TC + +++ + +GSMD L VW + + GH D VTCV S +
Sbjct: 47 RHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPS 106
Query: 1188 NKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+ SGS D + +W N V V DG V+ ++DKT+ +W
Sbjct: 107 GHL-LASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWA 165
Query: 1248 TKRGLALTSFSLHVPLLGFQITSDCARVVVHLLD 1281
T R L S S H+ + S R++V D
Sbjct: 166 THRQKFLFSLSQHINWVRCAKFSPDGRLIVSASD 199
Score = 70.9 bits (166), Expect = 3e-11
Identities = 49/232 (21%), Positives = 86/232 (37%), Gaps = 1/232 (0%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ +PSG L ++W + F+ H+ ++ + + Q +T S+D +
Sbjct: 101 VNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKT 160
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V VW H + +HI V C + L++S DD V + V H
Sbjct: 161 VKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEH 220
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA-GVPIHIFDVTDDNVFLLT 836
G VT V G D TV W+V LL ++ +L+T
Sbjct: 221 GGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLIT 280
Query: 837 LQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
D+ L + + G L+ L H+ + A G +D+++ ++
Sbjct: 281 ASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 332
Score = 65.3 bits (152), Expect = 2e-09
Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R + +P G+ +V A +LW S VH++ H G + + + D
Sbjct: 183 RCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMD 242
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
+V VWD+ T + H A V ++ + + +I+ DS + I L++G L+ L
Sbjct: 243 NTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLH 302
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLL 813
H+G T+V + G F +G D V W NF ++
Sbjct: 303 GHQGPATTVAFSRTGEYFASGGSDEQVMVWK-SNFDIV 339
Score = 64.1 bits (149), Expect = 4e-09
Identities = 50/247 (20%), Positives = 87/247 (35%), Gaps = 1/247 (0%)
Query: 678 LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIA 737
+WH+ S+ + F GH ++ C+ + L +GS D +V +W + T H A
Sbjct: 79 VWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTA 138
Query: 738 PVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGS 797
V V + ++ DD V + + + L H V K DG + ++ S
Sbjct: 139 TVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSAS 198
Query: 798 QDGTVCTWNVENFTLL-STVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
D TV W+ + + S G + D + DN + + T L
Sbjct: 199 DDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQH 258
Query: 857 LKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXF 916
+ H A V + + +D + + L +LL T
Sbjct: 259 YQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGE 318
Query: 917 LLAAGGN 923
A+GG+
Sbjct: 319 YFASGGS 325
Score = 62.9 bits (146), Expect = 8e-09
Identities = 56/237 (23%), Positives = 95/237 (40%), Gaps = 9/237 (3%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVW 721
P HL LA S DP L + H FKGH ++ C+ + ++ L +GS D+ ++VW
Sbjct: 29 PGFTHLTLALSQEDPSL-------ERH-FKGHRDAVTCVDFSINTKQLASGSMDSCLMVW 80
Query: 722 DLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSV 781
+ + + H V CV + L+ SG D V I T H +V
Sbjct: 81 HMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATV 140
Query: 782 TSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP-IHIFDVTDDNVFLLTLQGD 840
SV DG F+T S D TV W L +++ + + + D +++ D
Sbjct: 141 RSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDD 200
Query: 841 NELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
+ L + +H H V + +A D + ++ + + +LL+
Sbjct: 201 KTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQ 257
Score = 58.0 bits (134), Expect = 2e-07
Identities = 68/306 (22%), Positives = 110/306 (35%), Gaps = 28/306 (9%)
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H V CV +N + SG DS +++ + + + H+ +VT V G++
Sbjct: 52 HRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLA 111
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDV--TDDNVFLLTLQGDNELHLRTFITGT 852
+GS+D TV W V N STV + V D +T D + +
Sbjct: 112 SGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK 170
Query: 853 YLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXXXXX 912
+L L +H V+C + D + D+ + L+ S + + +
Sbjct: 171 FLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFH 230
Query: 913 XXXFLLAAGG--NRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPIS 970
+AA G N V ++ T LLQ Q ++
Sbjct: 231 PSGTCIAAAGMDNTVKVWDVRTH-----------------------RLLQHYQLHSAAVN 267
Query: 971 CLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDR 1030
L G + + +++ L RL TL+GH G T V FS SG D
Sbjct: 268 GLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDE 327
Query: 1031 TVVVWQ 1036
V+VW+
Sbjct: 328 QVMVWK 333
Score = 46.0 bits (104), Expect = 0.001
Identities = 26/97 (26%), Positives = 40/97 (41%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
V+VW + THRL H + ++F P+ +++ S D T+ + L + T GH
Sbjct: 245 VKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGH 304
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH 1086
T+ G S V VW + IV H
Sbjct: 305 QGPATTVAFSRTGEYFASGGSDEQVMVWKSNFDIVDH 341
Score = 44.8 bits (101), Expect = 0.002
Identities = 33/161 (20%), Positives = 63/161 (39%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R + GQ V A ++W + + H + C + + + +++ S+D
Sbjct: 141 RSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDD 200
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
+V +WD + EH V V + + + + G D+ V + + L+
Sbjct: 201 KTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQ 260
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV 816
H +V + GN IT S D T+ ++ LL T+
Sbjct: 261 LHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTL 301
>BC119692-1|AAI19693.1| 407|Homo sapiens WD repeat domain 51A
protein.
Length = 407
Score = 84.6 bits (200), Expect = 2e-15
Identities = 61/265 (23%), Positives = 108/265 (40%), Gaps = 11/265 (4%)
Query: 1000 LQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
L+ GH +TCV FS N + SGS D ++VW + S + + GH A+ +
Sbjct: 11 LERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFS 70
Query: 1060 SDGRRAMSSDRARNVHVWLVD---SGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIW 1116
G S R + V +W+ + V + T S+ + + V + D +V++W
Sbjct: 71 PSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130
Query: 1117 SLAGGDNSEDNRRSVS-HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGH 1175
+ + + S+S H + C + D + +V+ S D ++K+W + H
Sbjct: 131 AT----HRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEH 186
Query: 1176 SDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAV 1235
VT V + T + + D + VWD+ T V + G +
Sbjct: 187 GGFVTYVDFHPSG-TCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLI 245
Query: 1236 SCAEDKTLIIWETKRGLALTSFSLH 1260
+ + D TL I + G L ++LH
Sbjct: 246 TASSDSTLKILDLMEGRLL--YTLH 268
Score = 82.6 bits (195), Expect = 9e-15
Identities = 60/283 (21%), Positives = 118/283 (41%), Gaps = 7/283 (2%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
++C++ S + + ASG + VW + GH +TCV FSP+ L+ SGS
Sbjct: 22 VTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSR 81
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D+TV +W S ++ H++ ++++ SDG+ +++ + V VW L S
Sbjct: 82 DKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSL 141
Query: 1089 TGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
+ + + + + V + D +V++W + + E H +T
Sbjct: 142 SQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKS---SRECVHSYCEHGGFVTYVDFHPS 198
Query: 1146 SQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ MD ++KVW + +L Q HS V ++ + +++ S D L + D
Sbjct: 199 GTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFH-PSGNYLITASSDSTLKILD 257
Query: 1206 INTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWET 1248
+ T V + G S D+ +++W++
Sbjct: 258 LMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 300
Score = 72.9 bits (171), Expect = 8e-12
Identities = 44/154 (28%), Positives = 67/154 (43%), Gaps = 1/154 (0%)
Query: 1128 RRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSIT 1187
R H + +TC + +++ + +GSMD L VW + + GH D VTCV S +
Sbjct: 13 RHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPS 72
Query: 1188 NKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+ SGS D + +W N V V DG V+ ++DKT+ +W
Sbjct: 73 GHL-LASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWA 131
Query: 1248 TKRGLALTSFSLHVPLLGFQITSDCARVVVHLLD 1281
T R L S S H+ + S R++V D
Sbjct: 132 THRQKFLFSLSQHINWVRCAKFSPDGRLIVSASD 165
Score = 70.9 bits (166), Expect = 3e-11
Identities = 49/232 (21%), Positives = 86/232 (37%), Gaps = 1/232 (0%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ +PSG L ++W + F+ H+ ++ + + Q +T S+D +
Sbjct: 67 VNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKT 126
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V VW H + +HI V C + L++S DD V + V H
Sbjct: 127 VKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEH 186
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA-GVPIHIFDVTDDNVFLLT 836
G VT V G D TV W+V LL ++ +L+T
Sbjct: 187 GGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLIT 246
Query: 837 LQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
D+ L + + G L+ L H+ + A G +D+++ ++
Sbjct: 247 ASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
Score = 65.3 bits (152), Expect = 2e-09
Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R + +P G+ +V A +LW S VH++ H G + + + D
Sbjct: 149 RCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMD 208
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
+V VWD+ T + H A V ++ + + +I+ DS + I L++G L+ L
Sbjct: 209 NTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLH 268
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLL 813
H+G T+V + G F +G D V W NF ++
Sbjct: 269 GHQGPATTVAFSRTGEYFASGGSDEQVMVWK-SNFDIV 305
Score = 64.1 bits (149), Expect = 4e-09
Identities = 50/247 (20%), Positives = 87/247 (35%), Gaps = 1/247 (0%)
Query: 678 LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIA 737
+WH+ S+ + F GH ++ C+ + L +GS D +V +W + T H A
Sbjct: 45 VWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTA 104
Query: 738 PVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGS 797
V V + ++ DD V + + + L H V K DG + ++ S
Sbjct: 105 TVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSAS 164
Query: 798 QDGTVCTWNVENFTLL-STVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
D TV W+ + + S G + D + DN + + T L
Sbjct: 165 DDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQH 224
Query: 857 LKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXF 916
+ H A V + + +D + + L +LL T
Sbjct: 225 YQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGE 284
Query: 917 LLAAGGN 923
A+GG+
Sbjct: 285 YFASGGS 291
Score = 59.3 bits (137), Expect = 1e-07
Identities = 53/229 (23%), Positives = 92/229 (40%), Gaps = 9/229 (3%)
Query: 670 APSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK 729
AP A DP L + H FKGH ++ C+ + ++ L +GS D+ ++VW + +
Sbjct: 3 APCAEDPSL-------ERH-FKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRA 54
Query: 730 TKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQD 789
+ H V CV + L+ SG D V I T H +V SV D
Sbjct: 55 YRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSD 114
Query: 790 GNIFITGSQDGTVCTWNVENFTLLSTVTAGVP-IHIFDVTDDNVFLLTLQGDNELHLRTF 848
G F+T S D TV W L +++ + + + D +++ D + L
Sbjct: 115 GQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDK 174
Query: 849 ITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
+ +H H V + +A D + ++ + + +LL+
Sbjct: 175 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQ 223
Score = 58.0 bits (134), Expect = 2e-07
Identities = 68/306 (22%), Positives = 110/306 (35%), Gaps = 28/306 (9%)
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H V CV +N + SG DS +++ + + + H+ +VT V G++
Sbjct: 18 HRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLA 77
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDV--TDDNVFLLTLQGDNELHLRTFITGT 852
+GS+D TV W V N STV + V D +T D + +
Sbjct: 78 SGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK 136
Query: 853 YLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXXXXX 912
+L L +H V+C + D + D+ + L+ S + + +
Sbjct: 137 FLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFH 196
Query: 913 XXXFLLAAGG--NRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPIS 970
+AA G N V ++ T LLQ Q ++
Sbjct: 197 PSGTCIAAAGMDNTVKVWDVRTH-----------------------RLLQHYQLHSAAVN 233
Query: 971 CLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDR 1030
L G + + +++ L RL TL+GH G T V FS SG D
Sbjct: 234 GLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDE 293
Query: 1031 TVVVWQ 1036
V+VW+
Sbjct: 294 QVMVWK 299
Score = 46.0 bits (104), Expect = 0.001
Identities = 26/97 (26%), Positives = 40/97 (41%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
V+VW + THRL H + ++F P+ +++ S D T+ + L + T GH
Sbjct: 211 VKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGH 270
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH 1086
T+ G S V VW + IV H
Sbjct: 271 QGPATTVAFSRTGEYFASGGSDEQVMVWKSNFDIVDH 307
Score = 44.8 bits (101), Expect = 0.002
Identities = 33/161 (20%), Positives = 63/161 (39%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R + GQ V A ++W + + H + C + + + +++ S+D
Sbjct: 107 RSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDD 166
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
+V +WD + EH V V + + + + G D+ V + + L+
Sbjct: 167 KTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQ 226
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV 816
H +V + GN IT S D T+ ++ LL T+
Sbjct: 227 LHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTL 267
>BC110877-1|AAI10878.1| 359|Homo sapiens WDR51A protein protein.
Length = 359
Score = 84.6 bits (200), Expect = 2e-15
Identities = 61/265 (23%), Positives = 108/265 (40%), Gaps = 11/265 (4%)
Query: 1000 LQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
L+ GH +TCV FS N + SGS D ++VW + S + + GH A+ +
Sbjct: 11 LERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFS 70
Query: 1060 SDGRRAMSSDRARNVHVWLVD---SGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIW 1116
G S R + V +W+ + V + T S+ + + V + D +V++W
Sbjct: 71 PSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130
Query: 1117 SLAGGDNSEDNRRSVS-HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGH 1175
+ + + S+S H + C + D + +V+ S D ++K+W + H
Sbjct: 131 A----THRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEH 186
Query: 1176 SDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAV 1235
VT V + T + + D + VWD+ T V + G +
Sbjct: 187 GGFVTYVDFH-PSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLI 245
Query: 1236 SCAEDKTLIIWETKRGLALTSFSLH 1260
+ + D TL I + G L ++LH
Sbjct: 246 TASSDSTLKILDLMEGRLL--YTLH 268
Score = 84.2 bits (199), Expect = 3e-15
Identities = 65/317 (20%), Positives = 129/317 (40%), Gaps = 7/317 (2%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
++C++ S + + ASG + VW + GH +TCV FSP+ L+ SGS
Sbjct: 22 VTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSR 81
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D+TV +W S ++ H++ ++++ SDG+ +++ + V VW L S
Sbjct: 82 DKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSL 141
Query: 1089 TGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
+ + + + + V + D +V++W + + E H +T
Sbjct: 142 SQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKS---SRECVHSYCEHGGFVTYVDFHPS 198
Query: 1146 SQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ MD ++KVW + +L Q HS V ++ + +++ S D L + D
Sbjct: 199 GTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFH-PSGNYLITASSDSTLKILD 257
Query: 1206 INTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLG 1265
+ T V + G S D+ +++W++ + VP
Sbjct: 258 LMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSNFDIVDHGEVTKVPRPP 317
Query: 1266 FQITSDCARVVVHLLDR 1282
+ S + V +L++
Sbjct: 318 ATLASSMGNLTVSILEQ 334
Score = 70.9 bits (166), Expect = 3e-11
Identities = 49/232 (21%), Positives = 86/232 (37%), Gaps = 1/232 (0%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ +PSG L ++W + F+ H+ ++ + + Q +T S+D +
Sbjct: 67 VNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKT 126
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V VW H + +HI V C + L++S DD V + V H
Sbjct: 127 VKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEH 186
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA-GVPIHIFDVTDDNVFLLT 836
G VT V G D TV W+V LL ++ +L+T
Sbjct: 187 GGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLIT 246
Query: 837 LQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
D+ L + + G L+ L H+ + A G +D+++ ++
Sbjct: 247 ASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
Score = 65.3 bits (152), Expect = 2e-09
Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R + +P G+ +V A +LW S VH++ H G + + + D
Sbjct: 149 RCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMD 208
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
+V VWD+ T + H A V ++ + + +I+ DS + I L++G L+ L
Sbjct: 209 NTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLH 268
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLL 813
H+G T+V + G F +G D V W NF ++
Sbjct: 269 GHQGPATTVAFSRTGEYFASGGSDEQVMVWK-SNFDIV 305
Score = 64.1 bits (149), Expect = 4e-09
Identities = 50/247 (20%), Positives = 87/247 (35%), Gaps = 1/247 (0%)
Query: 678 LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIA 737
+WH+ S+ + F GH ++ C+ + L +GS D +V +W + T H A
Sbjct: 45 VWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTA 104
Query: 738 PVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGS 797
V V + ++ DD V + + + L H V K DG + ++ S
Sbjct: 105 TVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSAS 164
Query: 798 QDGTVCTWNVENFTLL-STVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
D TV W+ + + S G + D + DN + + T L
Sbjct: 165 DDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQH 224
Query: 857 LKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXF 916
+ H A V + + +D + + L +LL T
Sbjct: 225 YQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGE 284
Query: 917 LLAAGGN 923
A+GG+
Sbjct: 285 YFASGGS 291
Score = 59.3 bits (137), Expect = 1e-07
Identities = 53/229 (23%), Positives = 92/229 (40%), Gaps = 9/229 (3%)
Query: 670 APSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK 729
AP A DP L + H FKGH ++ C+ + ++ L +GS D+ ++VW + +
Sbjct: 3 APCAEDPSL-------ERH-FKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRA 54
Query: 730 TKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQD 789
+ H V CV + L+ SG D V I T H +V SV D
Sbjct: 55 YRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSD 114
Query: 790 GNIFITGSQDGTVCTWNVENFTLLSTVTAGVP-IHIFDVTDDNVFLLTLQGDNELHLRTF 848
G F+T S D TV W L +++ + + + D +++ D + L
Sbjct: 115 GQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDK 174
Query: 849 ITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
+ +H H V + +A D + ++ + + +LL+
Sbjct: 175 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQ 223
Score = 58.0 bits (134), Expect = 2e-07
Identities = 68/306 (22%), Positives = 110/306 (35%), Gaps = 28/306 (9%)
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H V CV +N + SG DS +++ + + + H+ +VT V G++
Sbjct: 18 HRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLA 77
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDV--TDDNVFLLTLQGDNELHLRTFITGT 852
+GS+D TV W V N STV + V D +T D + +
Sbjct: 78 SGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK 136
Query: 853 YLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXXXXX 912
+L L +H V+C + D + D+ + L+ S + + +
Sbjct: 137 FLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFH 196
Query: 913 XXXFLLAAGG--NRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPIS 970
+AA G N V ++ T LLQ Q ++
Sbjct: 197 PSGTCIAAAGMDNTVKVWDVRTH-----------------------RLLQHYQLHSAAVN 233
Query: 971 CLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDR 1030
L G + + +++ L RL TL+GH G T V FS SG D
Sbjct: 234 GLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDE 293
Query: 1031 TVVVWQ 1036
V+VW+
Sbjct: 294 QVMVWK 299
Score = 44.8 bits (101), Expect = 0.002
Identities = 33/161 (20%), Positives = 63/161 (39%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R + GQ V A ++W + + H + C + + + +++ S+D
Sbjct: 107 RSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDD 166
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
+V +WD + EH V V + + + + G D+ V + + L+
Sbjct: 167 KTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQ 226
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV 816
H +V + GN IT S D T+ ++ LL T+
Sbjct: 227 LHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTL 267
>AK075289-1|BAC11525.1| 407|Homo sapiens protein ( Homo sapiens cDNA
FLJ90808 fis, clone Y79AA1000777, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 407
Score = 84.6 bits (200), Expect = 2e-15
Identities = 61/265 (23%), Positives = 108/265 (40%), Gaps = 11/265 (4%)
Query: 1000 LQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
L+ GH +TCV FS N + SGS D ++VW + S + + GH A+ +
Sbjct: 11 LERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFS 70
Query: 1060 SDGRRAMSSDRARNVHVWLVD---SGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIW 1116
G S R + V +W+ + V + T S+ + + V + D +V++W
Sbjct: 71 PSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130
Query: 1117 SLAGGDNSEDNRRSVS-HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGH 1175
+ + + S+S H + C + D + +V+ S D ++K+W + H
Sbjct: 131 A----THRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEH 186
Query: 1176 SDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAV 1235
VT V + T + + D + VWD+ T V + G +
Sbjct: 187 GGFVTYVDFH-PSGTCIAAAGMDNTVKVWDVRTYRLLQHYQLHSAAVNGLSFHPSGNYLI 245
Query: 1236 SCAEDKTLIIWETKRGLALTSFSLH 1260
+ + D TL I + G L ++LH
Sbjct: 246 TASSDSTLKILDLMEGRLL--YTLH 268
Score = 82.2 bits (194), Expect = 1e-14
Identities = 60/283 (21%), Positives = 118/283 (41%), Gaps = 7/283 (2%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
++C++ S + + ASG + VW + GH +TCV FSP+ L+ SGS
Sbjct: 22 VTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSR 81
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D+TV +W S ++ H++ ++++ SDG+ +++ + V VW L S
Sbjct: 82 DKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSL 141
Query: 1089 TGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
+ + + + + V + D +V++W + + E H +T
Sbjct: 142 SQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKS---SRECVHSYCEHGGFVTYVDFHPS 198
Query: 1146 SQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ MD ++KVW + +L Q HS V ++ + +++ S D L + D
Sbjct: 199 GTCIAAAGMDNTVKVWDVRTYRLLQHYQLHSAAVNGLSFH-PSGNYLITASSDSTLKILD 257
Query: 1206 INTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWET 1248
+ T V + G S D+ +++W++
Sbjct: 258 LMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 300
Score = 72.9 bits (171), Expect = 8e-12
Identities = 44/154 (28%), Positives = 67/154 (43%), Gaps = 1/154 (0%)
Query: 1128 RRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSIT 1187
R H + +TC + +++ + +GSMD L VW + + GH D VTCV S +
Sbjct: 13 RHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPS 72
Query: 1188 NKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+ SGS D + +W N V V DG V+ ++DKT+ +W
Sbjct: 73 GHL-LASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWA 131
Query: 1248 TKRGLALTSFSLHVPLLGFQITSDCARVVVHLLD 1281
T R L S S H+ + S R++V D
Sbjct: 132 THRQKFLFSLSQHINWVRCAKFSPDGRLIVSASD 165
Score = 72.5 bits (170), Expect = 1e-11
Identities = 49/232 (21%), Positives = 87/232 (37%), Gaps = 1/232 (0%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ +PSG L ++W + F+ H+ ++ + + Q +T S+D +
Sbjct: 67 VNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKT 126
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V VW H + +HI V C + L++S DD V + V H
Sbjct: 127 VKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEH 186
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA-GVPIHIFDVTDDNVFLLT 836
G VT V G D TV W+V + LL ++ +L+T
Sbjct: 187 GGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTYRLLQHYQLHSAAVNGLSFHPSGNYLIT 246
Query: 837 LQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
D+ L + + G L+ L H+ + A G +D+++ ++
Sbjct: 247 ASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
Score = 66.1 bits (154), Expect = 9e-10
Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R + +P G+ +V A +LW S VH++ H G + + + D
Sbjct: 149 RCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMD 208
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
+V VWD+ T + H A V ++ + + +I+ DS + I L++G L+ L
Sbjct: 209 NTVKVWDVRTYRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLH 268
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLL 813
H+G T+V + G F +G D V W NF ++
Sbjct: 269 GHQGPATTVAFSRTGEYFASGGSDEQVMVWK-SNFDIV 305
Score = 63.7 bits (148), Expect = 5e-09
Identities = 50/247 (20%), Positives = 87/247 (35%), Gaps = 1/247 (0%)
Query: 678 LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIA 737
+WH+ S+ + F GH ++ C+ + L +GS D +V +W + T H A
Sbjct: 45 VWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTA 104
Query: 738 PVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGS 797
V V + ++ DD V + + + L H V K DG + ++ S
Sbjct: 105 TVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSAS 164
Query: 798 QDGTVCTWNVENFTLL-STVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
D TV W+ + + S G + D + DN + + T L
Sbjct: 165 DDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTYRLLQH 224
Query: 857 LKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXF 916
+ H A V + + +D + + L +LL T
Sbjct: 225 YQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGE 284
Query: 917 LLAAGGN 923
A+GG+
Sbjct: 285 YFASGGS 291
Score = 59.3 bits (137), Expect = 1e-07
Identities = 53/229 (23%), Positives = 92/229 (40%), Gaps = 9/229 (3%)
Query: 670 APSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK 729
AP A DP L + H FKGH ++ C+ + ++ L +GS D+ ++VW + +
Sbjct: 3 APCAEDPSL-------ERH-FKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRA 54
Query: 730 TKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQD 789
+ H V CV + L+ SG D V I T H +V SV D
Sbjct: 55 YRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSD 114
Query: 790 GNIFITGSQDGTVCTWNVENFTLLSTVTAGVP-IHIFDVTDDNVFLLTLQGDNELHLRTF 848
G F+T S D TV W L +++ + + + D +++ D + L
Sbjct: 115 GQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDK 174
Query: 849 ITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
+ +H H V + +A D + ++ + + +LL+
Sbjct: 175 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTYRLLQ 223
Score = 58.0 bits (134), Expect = 2e-07
Identities = 69/306 (22%), Positives = 112/306 (36%), Gaps = 28/306 (9%)
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H V CV +N + SG DS +++ + + + H+ +VT V G++
Sbjct: 18 HRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLA 77
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDV--TDDNVFLLTLQGDNELHLRTFITGT 852
+GS+D TV W V N STV + V D +T D + +
Sbjct: 78 SGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK 136
Query: 853 YLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXXXXX 912
+L L +H V+C + D + D+ + L+ S + + +
Sbjct: 137 FLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFH 196
Query: 913 XXXFLLAAGG--NRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPIS 970
+AA G N V ++ T +R LLQ Q ++
Sbjct: 197 PSGTCIAAAGMDNTVKVWDVRT------YR-----------------LLQHYQLHSAAVN 233
Query: 971 CLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDR 1030
L G + + +++ L RL TL+GH G T V FS SG D
Sbjct: 234 GLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDE 293
Query: 1031 TVVVWQ 1036
V+VW+
Sbjct: 294 QVMVWK 299
Score = 44.4 bits (100), Expect = 0.003
Identities = 33/161 (20%), Positives = 63/161 (39%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R + GQ V A ++W + + H + C + + + +++ S+D
Sbjct: 107 RSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDD 166
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
+V +WD + EH V V + + + + G D+ V + + L+
Sbjct: 167 KTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTYRLLQHYQ 226
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV 816
H +V + GN IT S D T+ ++ LL T+
Sbjct: 227 LHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTL 267
Score = 43.6 bits (98), Expect = 0.005
Identities = 25/97 (25%), Positives = 40/97 (41%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
V+VW + T+RL H + ++F P+ +++ S D T+ + L + T GH
Sbjct: 211 VKVWDVRTYRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGH 270
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH 1086
T+ G S V VW + IV H
Sbjct: 271 QGPATTVAFSRTGEYFASGGSDEQVMVWKSNFDIVDH 307
>AL121990-7|CAI22015.1| 589|Homo sapiens TAF5-like RNA polymerase II,
p300/CBP-associated factor (PCAF)-associated facto
protein.
Length = 589
Score = 84.2 bits (199), Expect = 3e-15
Identities = 55/206 (26%), Positives = 90/206 (43%), Gaps = 7/206 (3%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR 1063
L GH G + F ++ +LS SED ++ W L + ++ Y+GH+ + L +
Sbjct: 338 LRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSL 397
Query: 1064 RAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NMKYAVLSDGDNSVRIWSLAG 1120
S R +W D L G A +D N Y D +VR+WS
Sbjct: 398 YFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQ 457
Query: 1121 GDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVT 1180
G++ R H + A + + +++ + D LK+W L G L + L GH+D +T
Sbjct: 458 GNSV---RLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNIT 514
Query: 1181 CVAVSITNKTQVVSGSWDCNLIVWDI 1206
+ S + + S S D ++ VWDI
Sbjct: 515 SLTFS-PDSGLIASASMDNSVRVWDI 539
Score = 80.6 bits (190), Expect = 4e-14
Identities = 58/228 (25%), Positives = 94/228 (41%), Gaps = 10/228 (4%)
Query: 981 GASGCARGL-VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLAD 1039
G C+ + +R W L + GH + + SP +L SGS DRT +W
Sbjct: 356 GLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDR 415
Query: 1040 NSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSAT---GPSASID 1096
P Y GH + + + + + + V +W G + T GP S+
Sbjct: 416 TYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLA 475
Query: 1097 VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDM 1156
+ N KY + D +++W LA G ++ R H + IT + DS + + SMD
Sbjct: 476 FSPNGKYLASAGEDQRLKLWDLASGTLYKELR---GHTDNITSLTFSPDSGLIASASMDN 532
Query: 1157 SLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSW-DCNLIV 1203
S++VW + S G S V V + V+S + CNL++
Sbjct: 533 SVRVWDIRNTYCSAPADGSSS--ELVGVYTGQMSNVLSVQFMACNLLL 578
Score = 68.1 bits (159), Expect = 2e-10
Identities = 43/170 (25%), Positives = 75/170 (44%), Gaps = 6/170 (3%)
Query: 952 STTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHI 1011
S TN L Q P+ L++S ASG R+W GH+ +
Sbjct: 373 SFTNTVLYQGHA---YPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADV 429
Query: 1012 TCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRA 1071
CV F PN+ + +GS D+TV +W + + GH + +L +G+ S+
Sbjct: 430 DCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGED 489
Query: 1072 RNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSL 1118
+ + +W + SG + G + +I +T + +++ DNSVR+W +
Sbjct: 490 QRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDI 539
Score = 68.1 bits (159), Expect = 2e-10
Identities = 38/152 (25%), Positives = 62/152 (40%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L ++P + +LW + + GH + C+ S YL TGS D +
Sbjct: 390 LDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKT 449
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V +W H PVL +A N + S G+D + + L G L +L H
Sbjct: 450 VRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGH 509
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
++TS+ D + + S D +V W++ N
Sbjct: 510 TDNITSLTFSPDSGLIASASMDNSVRVWDIRN 541
Score = 57.6 bits (133), Expect = 3e-07
Identities = 32/130 (24%), Positives = 54/130 (41%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLS 1025
L + C++ + A+G VR+W GH G + + FSPN + S
Sbjct: 426 LADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLAS 485
Query: 1026 GSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVL 1085
ED+ + +W LA + +GH+ I +L D S+ +V VW + +
Sbjct: 486 AGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYCS 545
Query: 1086 HSATGPSASI 1095
A G S+ +
Sbjct: 546 APADGSSSEL 555
Score = 56.8 bits (131), Expect = 5e-07
Identities = 49/212 (23%), Positives = 80/212 (37%), Gaps = 3/212 (1%)
Query: 683 SNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCV 742
+ +++ +GH G + +S LL+ SED S+ WDL + H PV +
Sbjct: 331 AGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDL 390
Query: 743 AAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTV 802
SG D + S + H V VK + N TGS D TV
Sbjct: 391 DISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTV 450
Query: 803 CTWNVE--NFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRH 860
W+ + N L T G P+ + + +L + D L L +GT L+ H
Sbjct: 451 RLWSAQQGNSVRLFTGHRG-PVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGH 509
Query: 861 KAKVKCFCVAHDSSRVAVGCADQRIYLYSLHS 892
+ + DS +A D + ++ + +
Sbjct: 510 TDNITSLTFSPDSGLIASASMDNSVRVWDIRN 541
Score = 52.8 bits (121), Expect = 9e-06
Identities = 32/134 (23%), Positives = 57/134 (42%)
Query: 679 WHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAP 738
W + S + ++GH+ + + ++ S Y +GS D + +W H+A
Sbjct: 369 WDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLAD 428
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQ 798
V CV N + + +G D V + S G V HRG V S+ +G + +
Sbjct: 429 VDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGE 488
Query: 799 DGTVCTWNVENFTL 812
D + W++ + TL
Sbjct: 489 DQRLKLWDLASGTL 502
Score = 50.0 bits (114), Expect = 6e-05
Identities = 48/235 (20%), Positives = 87/235 (37%), Gaps = 11/235 (4%)
Query: 1017 SPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHV 1076
SP++ L+ +G ++ + +W L S L + H + + + D D N
Sbjct: 277 SPDSKLLAAGFDNSCIKLWSL--RSKKLKSEPHQVDVSRIHLACDILEE-EDDEDDNAGT 333
Query: 1077 WLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAER 1136
+ +L GP S + + D S+R W L N+ + HA
Sbjct: 334 EMK----ILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQ---GHAYP 386
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGS 1196
+ ++ S + +GS D + ++W D ++ GH V CV N + +GS
Sbjct: 387 VWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFH-PNSNYLATGS 445
Query: 1197 WDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
D + +W V + + +G S ED+ L +W+ G
Sbjct: 446 TDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASG 500
Score = 46.4 bits (105), Expect = 8e-04
Identities = 26/131 (19%), Positives = 53/131 (40%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVW 721
P+ +L + +LW + V F GH G +L + + +YL + ED + +W
Sbjct: 436 PNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLW 495
Query: 722 DLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSV 781
DL + + ++ H + + + L+ S D++V + + + D +
Sbjct: 496 DLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSSSEL 555
Query: 782 TSVKVIQDGNI 792
V Q N+
Sbjct: 556 VGVYTGQMSNV 566
Score = 44.0 bits (99), Expect = 0.004
Identities = 29/117 (24%), Positives = 51/117 (43%), Gaps = 1/117 (0%)
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIV 1203
ADS +++ S DMS++ W L + + GH+ V + +S SGS D +
Sbjct: 352 ADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDIS-PYSLYFASGSHDRTARL 410
Query: 1204 WDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
W + V CVK + + + DKT+ +W ++G ++ F+ H
Sbjct: 411 WSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGH 467
>AJ009770-1|CAA08816.1| 260|Homo sapiens putative transcription
factor protein.
Length = 260
Score = 84.2 bits (199), Expect = 3e-15
Identities = 55/206 (26%), Positives = 90/206 (43%), Gaps = 7/206 (3%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR 1063
L GH G + F ++ +LS SED ++ W L + ++ Y+GH+ + L +
Sbjct: 9 LRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSL 68
Query: 1064 RAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NMKYAVLSDGDNSVRIWSLAG 1120
S R +W D L G A +D N Y D +VR+WS
Sbjct: 69 YFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQ 128
Query: 1121 GDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVT 1180
G++ R H + A + + +++ + D LK+W L G L + L GH+D +T
Sbjct: 129 GNSV---RLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNIT 185
Query: 1181 CVAVSITNKTQVVSGSWDCNLIVWDI 1206
+ S + + S S D ++ VWDI
Sbjct: 186 SLTFS-PDSGLIASASMDNSVRVWDI 210
Score = 80.6 bits (190), Expect = 4e-14
Identities = 58/228 (25%), Positives = 94/228 (41%), Gaps = 10/228 (4%)
Query: 981 GASGCARGL-VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLAD 1039
G C+ + +R W L + GH + + SP +L SGS DRT +W
Sbjct: 27 GLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDR 86
Query: 1040 NSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSAT---GPSASID 1096
P Y GH + + + + + + V +W G + T GP S+
Sbjct: 87 TYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLA 146
Query: 1097 VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDM 1156
+ N KY + D +++W LA G ++ R H + IT + DS + + SMD
Sbjct: 147 FSPNGKYLASAGEDQRLKLWDLASGTLYKELR---GHTDNITSLTFSPDSGLIASASMDN 203
Query: 1157 SLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSW-DCNLIV 1203
S++VW + S G S V V + V+S + CNL++
Sbjct: 204 SVRVWDIRNTYCSAPADGSSS--ELVGVYTGQMSNVLSVQFMACNLLL 249
Score = 68.1 bits (159), Expect = 2e-10
Identities = 43/170 (25%), Positives = 75/170 (44%), Gaps = 6/170 (3%)
Query: 952 STTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHI 1011
S TN L Q P+ L++S ASG R+W GH+ +
Sbjct: 44 SFTNTVLYQGHA---YPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADV 100
Query: 1012 TCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRA 1071
CV F PN+ + +GS D+TV +W + + GH + +L +G+ S+
Sbjct: 101 DCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGED 160
Query: 1072 RNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSL 1118
+ + +W + SG + G + +I +T + +++ DNSVR+W +
Sbjct: 161 QRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDI 210
Score = 68.1 bits (159), Expect = 2e-10
Identities = 38/152 (25%), Positives = 62/152 (40%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L ++P + +LW + + GH + C+ S YL TGS D +
Sbjct: 61 LDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKT 120
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V +W H PVL +A N + S G+D + + L G L +L H
Sbjct: 121 VRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGH 180
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
++TS+ D + + S D +V W++ N
Sbjct: 181 TDNITSLTFSPDSGLIASASMDNSVRVWDIRN 212
Score = 57.6 bits (133), Expect = 3e-07
Identities = 32/130 (24%), Positives = 54/130 (41%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLS 1025
L + C++ + A+G VR+W GH G + + FSPN + S
Sbjct: 97 LADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLAS 156
Query: 1026 GSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVL 1085
ED+ + +W LA + +GH+ I +L D S+ +V VW + +
Sbjct: 157 AGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYCS 216
Query: 1086 HSATGPSASI 1095
A G S+ +
Sbjct: 217 APADGSSSEL 226
Score = 56.8 bits (131), Expect = 5e-07
Identities = 49/212 (23%), Positives = 80/212 (37%), Gaps = 3/212 (1%)
Query: 683 SNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCV 742
+ +++ +GH G + +S LL+ SED S+ WDL + H PV +
Sbjct: 2 AGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDL 61
Query: 743 AAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTV 802
SG D + S + H V VK + N TGS D TV
Sbjct: 62 DISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTV 121
Query: 803 CTWNVE--NFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRH 860
W+ + N L T G P+ + + +L + D L L +GT L+ H
Sbjct: 122 RLWSAQQGNSVRLFTGHRG-PVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGH 180
Query: 861 KAKVKCFCVAHDSSRVAVGCADQRIYLYSLHS 892
+ + DS +A D + ++ + +
Sbjct: 181 TDNITSLTFSPDSGLIASASMDNSVRVWDIRN 212
Score = 52.8 bits (121), Expect = 9e-06
Identities = 32/134 (23%), Positives = 57/134 (42%)
Query: 679 WHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAP 738
W + S + ++GH+ + + ++ S Y +GS D + +W H+A
Sbjct: 40 WDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLAD 99
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQ 798
V CV N + + +G D V + S G V HRG V S+ +G + +
Sbjct: 100 VDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGE 159
Query: 799 DGTVCTWNVENFTL 812
D + W++ + TL
Sbjct: 160 DQRLKLWDLASGTL 173
Score = 47.2 bits (107), Expect = 4e-04
Identities = 36/168 (21%), Positives = 62/168 (36%), Gaps = 4/168 (2%)
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
+L GP S + + D S+R W L N+ + HA + ++
Sbjct: 8 ILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQ---GHAYPVWDLDIS 64
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIV 1203
S + +GS D + ++W D ++ GH V CV N + +GS D + +
Sbjct: 65 PYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFH-PNSNYLATGSTDKTVRL 123
Query: 1204 WDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
W V + + +G S ED+ L +W+ G
Sbjct: 124 WSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASG 171
Score = 46.4 bits (105), Expect = 8e-04
Identities = 26/131 (19%), Positives = 53/131 (40%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVW 721
P+ +L + +LW + V F GH G +L + + +YL + ED + +W
Sbjct: 107 PNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLW 166
Query: 722 DLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSV 781
DL + + ++ H + + + L+ S D++V + + + D +
Sbjct: 167 DLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSSSEL 226
Query: 782 TSVKVIQDGNI 792
V Q N+
Sbjct: 227 VGVYTGQMSNV 237
Score = 44.0 bits (99), Expect = 0.004
Identities = 29/117 (24%), Positives = 51/117 (43%), Gaps = 1/117 (0%)
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIV 1203
ADS +++ S DMS++ W L + + GH+ V + +S SGS D +
Sbjct: 23 ADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDIS-PYSLYFASGSHDRTARL 81
Query: 1204 WDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
W + V CVK + + + DKT+ +W ++G ++ F+ H
Sbjct: 82 WSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGH 138
>AF069736-1|AAC39906.1| 589|Homo sapiens PCAF associated factor 65
beta protein.
Length = 589
Score = 84.2 bits (199), Expect = 3e-15
Identities = 55/206 (26%), Positives = 90/206 (43%), Gaps = 7/206 (3%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR 1063
L GH G + F ++ +LS SED ++ W L + ++ Y+GH+ + L +
Sbjct: 338 LRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSL 397
Query: 1064 RAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NMKYAVLSDGDNSVRIWSLAG 1120
S R +W D L G A +D N Y D +VR+WS
Sbjct: 398 YFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQ 457
Query: 1121 GDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVT 1180
G++ R H + A + + +++ + D LK+W L G L + L GH+D +T
Sbjct: 458 GNSV---RLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNIT 514
Query: 1181 CVAVSITNKTQVVSGSWDCNLIVWDI 1206
+ S + + S S D ++ VWDI
Sbjct: 515 SLTFS-PDSGLIASASMDNSVRVWDI 539
Score = 80.6 bits (190), Expect = 4e-14
Identities = 58/228 (25%), Positives = 94/228 (41%), Gaps = 10/228 (4%)
Query: 981 GASGCARGL-VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLAD 1039
G C+ + +R W L + GH + + SP +L SGS DRT +W
Sbjct: 356 GLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDR 415
Query: 1040 NSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSAT---GPSASID 1096
P Y GH + + + + + + V +W G + T GP S+
Sbjct: 416 TYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLA 475
Query: 1097 VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDM 1156
+ N KY + D +++W LA G ++ R H + IT + DS + + SMD
Sbjct: 476 FSPNGKYLASAGEDQRLKLWDLASGTLYKELR---GHTDNITSLTFSPDSGLIASASMDN 532
Query: 1157 SLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSW-DCNLIV 1203
S++VW + S G S V V + V+S + CNL++
Sbjct: 533 SVRVWDIRNTYCSAPADGSSS--ELVGVYTGQMSNVLSVQFMACNLLL 578
Score = 68.1 bits (159), Expect = 2e-10
Identities = 43/170 (25%), Positives = 75/170 (44%), Gaps = 6/170 (3%)
Query: 952 STTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHI 1011
S TN L Q P+ L++S ASG R+W GH+ +
Sbjct: 373 SFTNTVLYQGHA---YPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADV 429
Query: 1012 TCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRA 1071
CV F PN+ + +GS D+TV +W + + GH + +L +G+ S+
Sbjct: 430 DCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGED 489
Query: 1072 RNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSL 1118
+ + +W + SG + G + +I +T + +++ DNSVR+W +
Sbjct: 490 QRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDI 539
Score = 68.1 bits (159), Expect = 2e-10
Identities = 38/152 (25%), Positives = 62/152 (40%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L ++P + +LW + + GH + C+ S YL TGS D +
Sbjct: 390 LDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKT 449
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V +W H PVL +A N + S G+D + + L G L +L H
Sbjct: 450 VRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGH 509
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
++TS+ D + + S D +V W++ N
Sbjct: 510 TDNITSLTFSPDSGLIASASMDNSVRVWDIRN 541
Score = 57.6 bits (133), Expect = 3e-07
Identities = 32/130 (24%), Positives = 54/130 (41%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLS 1025
L + C++ + A+G VR+W GH G + + FSPN + S
Sbjct: 426 LADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLAS 485
Query: 1026 GSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVL 1085
ED+ + +W LA + +GH+ I +L D S+ +V VW + +
Sbjct: 486 AGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYCS 545
Query: 1086 HSATGPSASI 1095
A G S+ +
Sbjct: 546 APADGSSSEL 555
Score = 56.8 bits (131), Expect = 5e-07
Identities = 49/212 (23%), Positives = 80/212 (37%), Gaps = 3/212 (1%)
Query: 683 SNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCV 742
+ +++ +GH G + +S LL+ SED S+ WDL + H PV +
Sbjct: 331 AGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDL 390
Query: 743 AAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTV 802
SG D + S + H V VK + N TGS D TV
Sbjct: 391 DISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTV 450
Query: 803 CTWNVE--NFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRH 860
W+ + N L T G P+ + + +L + D L L +GT L+ H
Sbjct: 451 RLWSAQQGNSVRLFTGHRG-PVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGH 509
Query: 861 KAKVKCFCVAHDSSRVAVGCADQRIYLYSLHS 892
+ + DS +A D + ++ + +
Sbjct: 510 TDNITSLTFSPDSGLIASASMDNSVRVWDIRN 541
Score = 52.8 bits (121), Expect = 9e-06
Identities = 32/134 (23%), Positives = 57/134 (42%)
Query: 679 WHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAP 738
W + S + ++GH+ + + ++ S Y +GS D + +W H+A
Sbjct: 369 WDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLAD 428
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQ 798
V CV N + + +G D V + S G V HRG V S+ +G + +
Sbjct: 429 VDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGE 488
Query: 799 DGTVCTWNVENFTL 812
D + W++ + TL
Sbjct: 489 DQRLKLWDLASGTL 502
Score = 50.0 bits (114), Expect = 6e-05
Identities = 48/235 (20%), Positives = 87/235 (37%), Gaps = 11/235 (4%)
Query: 1017 SPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHV 1076
SP++ L+ +G ++ + +W L S L + H + + + D D N
Sbjct: 277 SPDSKLLAAGFDNSCIKLWSL--RSKKLKSEPHQVDVSRIHLACDILEE-EDDEDDNAGT 333
Query: 1077 WLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAER 1136
+ +L GP S + + D S+R W L N+ + HA
Sbjct: 334 EMK----ILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQ---GHAYP 386
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGS 1196
+ ++ S + +GS D + ++W D ++ GH V CV N + +GS
Sbjct: 387 VWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFH-PNSNYLATGS 445
Query: 1197 WDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
D + +W V + + +G S ED+ L +W+ G
Sbjct: 446 TDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASG 500
Score = 46.4 bits (105), Expect = 8e-04
Identities = 26/131 (19%), Positives = 53/131 (40%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVW 721
P+ +L + +LW + V F GH G +L + + +YL + ED + +W
Sbjct: 436 PNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLW 495
Query: 722 DLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSV 781
DL + + ++ H + + + L+ S D++V + + + D +
Sbjct: 496 DLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSSSEL 555
Query: 782 TSVKVIQDGNI 792
V Q N+
Sbjct: 556 VGVYTGQMSNV 566
Score = 44.0 bits (99), Expect = 0.004
Identities = 29/117 (24%), Positives = 51/117 (43%), Gaps = 1/117 (0%)
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIV 1203
ADS +++ S DMS++ W L + + GH+ V + +S SGS D +
Sbjct: 352 ADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDIS-PYSLYFASGSHDRTARL 410
Query: 1204 WDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
W + V CVK + + + DKT+ +W ++G ++ F+ H
Sbjct: 411 WSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGH 467
>BC007417-1|AAH07417.2| 396|Homo sapiens WDR51A protein protein.
Length = 396
Score = 83.4 bits (197), Expect = 5e-15
Identities = 60/259 (23%), Positives = 106/259 (40%), Gaps = 11/259 (4%)
Query: 1006 GHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRA 1065
GH +TCV FS N + SGS D ++VW + S + + GH A+ + G
Sbjct: 6 GHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLL 65
Query: 1066 MSSDRARNVHVWLVD---SGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGD 1122
S R + V +W+ + V + T S+ + + V + D +V++W+
Sbjct: 66 ASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWAT---- 121
Query: 1123 NSEDNRRSVS-HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTC 1181
+ + S+S H + C + D + +V+ S D ++K+W + H VT
Sbjct: 122 HRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTY 181
Query: 1182 VAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDK 1241
V + T + + D + VWD+ T V + G ++ + D
Sbjct: 182 VDFHPSG-TCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDS 240
Query: 1242 TLIIWETKRGLALTSFSLH 1260
TL I + G L ++LH
Sbjct: 241 TLKILDLMEGRLL--YTLH 257
Score = 82.6 bits (195), Expect = 9e-15
Identities = 60/283 (21%), Positives = 118/283 (41%), Gaps = 7/283 (2%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
++C++ S + + ASG + VW + GH +TCV FSP+ L+ SGS
Sbjct: 11 VTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSR 70
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D+TV +W S ++ H++ ++++ SDG+ +++ + V VW L S
Sbjct: 71 DKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSL 130
Query: 1089 TGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
+ + + + + V + D +V++W + + E H +T
Sbjct: 131 SQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKS---SRECVHSYCEHGGFVTYVDFHPS 187
Query: 1146 SQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ MD ++KVW + +L Q HS V ++ + +++ S D L + D
Sbjct: 188 GTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFH-PSGNYLITASSDSTLKILD 246
Query: 1206 INTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWET 1248
+ T V + G S D+ +++W++
Sbjct: 247 LMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 289
Score = 72.9 bits (171), Expect = 8e-12
Identities = 44/154 (28%), Positives = 67/154 (43%), Gaps = 1/154 (0%)
Query: 1128 RRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSIT 1187
R H + +TC + +++ + +GSMD L VW + + GH D VTCV S +
Sbjct: 2 RHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPS 61
Query: 1188 NKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+ SGS D + +W N V V DG V+ ++DKT+ +W
Sbjct: 62 GHL-LASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWA 120
Query: 1248 TKRGLALTSFSLHVPLLGFQITSDCARVVVHLLD 1281
T R L S S H+ + S R++V D
Sbjct: 121 THRQKFLFSLSQHINWVRCAKFSPDGRLIVSASD 154
Score = 70.9 bits (166), Expect = 3e-11
Identities = 49/232 (21%), Positives = 86/232 (37%), Gaps = 1/232 (0%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ +PSG L ++W + F+ H+ ++ + + Q +T S+D +
Sbjct: 56 VNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKT 115
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V VW H + +HI V C + L++S DD V + V H
Sbjct: 116 VKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEH 175
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA-GVPIHIFDVTDDNVFLLT 836
G VT V G D TV W+V LL ++ +L+T
Sbjct: 176 GGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLIT 235
Query: 837 LQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
D+ L + + G L+ L H+ + A G +D+++ ++
Sbjct: 236 ASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 287
Score = 65.3 bits (152), Expect = 2e-09
Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R + +P G+ +V A +LW S VH++ H G + + + D
Sbjct: 138 RCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMD 197
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
+V VWD+ T + H A V ++ + + +I+ DS + I L++G L+ L
Sbjct: 198 NTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLH 257
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLL 813
H+G T+V + G F +G D V W NF ++
Sbjct: 258 GHQGPATTVAFSRTGEYFASGGSDEQVMVWK-SNFDIV 294
Score = 64.1 bits (149), Expect = 4e-09
Identities = 50/247 (20%), Positives = 87/247 (35%), Gaps = 1/247 (0%)
Query: 678 LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIA 737
+WH+ S+ + F GH ++ C+ + L +GS D +V +W + T H A
Sbjct: 34 VWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTA 93
Query: 738 PVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGS 797
V V + ++ DD V + + + L H V K DG + ++ S
Sbjct: 94 TVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSAS 153
Query: 798 QDGTVCTWNVENFTLL-STVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
D TV W+ + + S G + D + DN + + T L
Sbjct: 154 DDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQH 213
Query: 857 LKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXF 916
+ H A V + + +D + + L +LL T
Sbjct: 214 YQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGE 273
Query: 917 LLAAGGN 923
A+GG+
Sbjct: 274 YFASGGS 280
Score = 58.8 bits (136), Expect = 1e-07
Identities = 46/209 (22%), Positives = 84/209 (40%), Gaps = 1/209 (0%)
Query: 690 FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRS 749
FKGH ++ C+ + ++ L +GS D+ ++VW + + + H V CV +
Sbjct: 4 FKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGH 63
Query: 750 LVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
L+ SG D V I T H +V SV DG F+T S D TV W
Sbjct: 64 LLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHR 123
Query: 810 FTLLSTVTAGVP-IHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFC 868
L +++ + + + D +++ D + L + +H H V
Sbjct: 124 QKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVD 183
Query: 869 VAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
+ +A D + ++ + + +LL+
Sbjct: 184 FHPSGTCIAAAGMDNTVKVWDVRTHRLLQ 212
Score = 58.0 bits (134), Expect = 2e-07
Identities = 68/306 (22%), Positives = 110/306 (35%), Gaps = 28/306 (9%)
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H V CV +N + SG DS +++ + + + H+ +VT V G++
Sbjct: 7 HRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLA 66
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDV--TDDNVFLLTLQGDNELHLRTFITGT 852
+GS+D TV W V N STV + V D +T D + +
Sbjct: 67 SGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK 125
Query: 853 YLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXXXXX 912
+L L +H V+C + D + D+ + L+ S + + +
Sbjct: 126 FLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFH 185
Query: 913 XXXFLLAAGG--NRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPIS 970
+AA G N V ++ T LLQ Q ++
Sbjct: 186 PSGTCIAAAGMDNTVKVWDVRTH-----------------------RLLQHYQLHSAAVN 222
Query: 971 CLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDR 1030
L G + + +++ L RL TL+GH G T V FS SG D
Sbjct: 223 GLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDE 282
Query: 1031 TVVVWQ 1036
V+VW+
Sbjct: 283 QVMVWK 288
Score = 46.0 bits (104), Expect = 0.001
Identities = 26/97 (26%), Positives = 40/97 (41%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
V+VW + THRL H + ++F P+ +++ S D T+ + L + T GH
Sbjct: 200 VKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGH 259
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH 1086
T+ G S V VW + IV H
Sbjct: 260 QGPATTVAFSRTGEYFASGGSDEQVMVWKSNFDIVDH 296
Score = 44.8 bits (101), Expect = 0.002
Identities = 33/161 (20%), Positives = 63/161 (39%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R + GQ V A ++W + + H + C + + + +++ S+D
Sbjct: 96 RSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDD 155
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
+V +WD + EH V V + + + + G D+ V + + L+
Sbjct: 156 KTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQ 215
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV 816
H +V + GN IT S D T+ ++ LL T+
Sbjct: 216 LHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTL 256
>AK222501-1|BAD96221.1| 392|Homo sapiens hypothetical protein
FLJ11848 variant protein.
Length = 392
Score = 83.0 bits (196), Expect = 7e-15
Identities = 37/109 (33%), Positives = 57/109 (52%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+CL++S G LG S G +++WQ S L+ L GH+ + F P+ L+VLSG
Sbjct: 95 ITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNSCRFFPSGLVVLSGGM 154
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
D + +W D S +T+KGH I ++ GR +S+ R +W
Sbjct: 155 DAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLW 203
Score = 52.0 bits (119), Expect = 2e-05
Identities = 26/114 (22%), Positives = 53/114 (46%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ SI C+ ++ ++ S D ++ +W ++ + H+ V + +V+
Sbjct: 91 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNSCRFFPSGLVVL 150
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
SGG D+ + I S D + V H+G + ++ G ++ S+DGT W+
Sbjct: 151 SGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWD 204
Score = 51.2 bits (117), Expect = 3e-05
Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 3/123 (2%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGH-SDIVTCVAVSITNKTQ 1191
H + ITC +++ V+ S D ++K+W+ G+L +VL GH D+ +C +
Sbjct: 91 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNSC--RFFPSGLV 148
Query: 1192 VVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
V+SG D L +W + + G VS + D T +W+ R
Sbjct: 149 VLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWDCGRS 208
Query: 1252 LAL 1254
L
Sbjct: 209 ACL 211
Score = 39.5 bits (88), Expect = 0.087
Identities = 27/111 (24%), Positives = 42/111 (37%), Gaps = 4/111 (3%)
Query: 1095 IDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSM 1154
+D++ V S D +++IW N E R H + V++G M
Sbjct: 98 LDISSRGGLGVSSSTDGTMKIWQ---ASNGELRRVLEGHVFDVNSCRFFPSGLVVLSGGM 154
Query: 1155 DMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
D LK+W + GH + A+ + VVS S D +WD
Sbjct: 155 DAQLKIWSAEDASCVVTFKGHKGGILDTAI-VDRGRNVVSASRDGTARLWD 204
Score = 37.9 bits (84), Expect = 0.26
Identities = 24/113 (21%), Positives = 44/113 (38%), Gaps = 3/113 (2%)
Query: 1007 HIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAM 1066
H ITC+ S L +S S D T+ +WQ ++ +GH + + G +
Sbjct: 91 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNSCRFFPSGLVVL 150
Query: 1067 SSDRARNVHVWLVDSGIVLHSATGPSASI-DVTL--NMKYAVLSDGDNSVRIW 1116
S + +W + + + G I D + + V + D + R+W
Sbjct: 151 SGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLW 203
Score = 37.5 bits (83), Expect = 0.35
Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Query: 662 PSGQHLVLAPSAGDPQL--WHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
PSG LV+ D QL W S V TFKGH G IL + + +++ S D +
Sbjct: 144 PSG--LVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTAR 201
Query: 720 VWD 722
+WD
Sbjct: 202 LWD 204
Score = 32.7 bits (71), Expect = 10.0
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 7/73 (9%)
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVF--- 833
H S+T + + G + ++ S DGT+ W N L + H+FDV F
Sbjct: 91 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEG----HVFDVNSCRFFPSG 146
Query: 834 LLTLQGDNELHLR 846
L+ L G + L+
Sbjct: 147 LVVLSGGMDAQLK 159
>AK093017-1|BAC04021.1| 619|Homo sapiens protein ( Homo sapiens cDNA
FLJ35698 fis, clone SPLEN2019839, weakly similar to TIPD
PROTEIN. ).
Length = 619
Score = 82.6 bits (195), Expect = 9e-15
Identities = 69/291 (23%), Positives = 122/291 (41%), Gaps = 16/291 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQA--TLNGHIGHITCVTFSPNNLLV 1023
L ++ + + L A+G A L+ +W + RL+A TL G G IT V F P+ V
Sbjct: 336 LSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSVDFDPSGYQV 395
Query: 1024 LSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGI 1083
L+ + ++ +W++ + T GH + +A++ R R V W +
Sbjct: 396 LAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAY 455
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE-RITCFAL 1142
+ S DV + D +R W D+ E + V + R+T +L
Sbjct: 456 CSRTINVLSYCNDVVCGDHIIISGHNDQKIRFW-----DSREPHCTQVIPVQGRVTSLSL 510
Query: 1143 TADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTC-----VAVSITNKTQVVSGSW 1197
+ D H+++ S D +LKV L + QV +D C AV +++ ++GS
Sbjct: 511 SHDQLHLLSCSRDNTLKVIDLRVSNIRQVF--RADGFKCGSDWTKAVFSPDRSYALAGSC 568
Query: 1198 DCNLIVWDINTXXXXXXXXX-XXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
D L +WD++T V V G+ VS + + +++W+
Sbjct: 569 DGALYIWDVDTGKLESRLQGPHCAAVNAVAWCYSGSHMVSVDQGRKVVLWQ 619
Score = 50.8 bits (116), Expect = 4e-05
Identities = 53/262 (20%), Positives = 103/262 (39%), Gaps = 17/262 (6%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN--SPSLTYKGHSSAIQTL 1056
R Q L+ H+ + V F PN+ L+ +G DR + +W + + + T +G +I ++
Sbjct: 327 RAQDVLDAHLSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSV 386
Query: 1057 LMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVT---LNMKYAVLSDGDNSV 1113
G + +++ + +W V + +G + L AV D +V
Sbjct: 387 DFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTV 446
Query: 1114 RIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLV 1173
+ W L G +S+ + C +++G D ++ W +QV+
Sbjct: 447 KEWDL-GRAYCSRTINVLSYCNDVVC-----GDHIIISGHNDQKIRFWDSREPHCTQVIP 500
Query: 1174 GHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKV----TCVKVTG 1229
VT +++S ++ ++S S D L V D+ K T +
Sbjct: 501 VQGR-VTSLSLS-HDQLHLLSCSRDNTLKVIDLRVSNIRQVFRADGFKCGSDWTKAVFSP 558
Query: 1230 DGTIAVSCAEDKTLIIWETKRG 1251
D + A++ + D L IW+ G
Sbjct: 559 DRSYALAGSCDGALYIWDVDTG 580
Score = 40.3 bits (90), Expect = 0.050
Identities = 33/141 (23%), Positives = 59/141 (41%), Gaps = 4/141 (2%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVW 721
PSG ++ A QLW + T GH + +TGS D +V W
Sbjct: 390 PSGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEW 449
Query: 722 DLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSV 781
DL A ++ + ++ C + ++ISG +D + + T++ +G V
Sbjct: 450 DLGR-AYCSRTINVLS--YCNDVVCGDHIIISGHNDQKIRFWDSRE-PHCTQVIPVQGRV 505
Query: 782 TSVKVIQDGNIFITGSQDGTV 802
TS+ + D ++ S+D T+
Sbjct: 506 TSLSLSHDQLHLLSCSRDNTL 526
>BC036713-1|AAH36713.1| 542|Homo sapiens ATG16L2 protein protein.
Length = 542
Score = 81.8 bits (193), Expect = 2e-14
Identities = 67/290 (23%), Positives = 120/290 (41%), Gaps = 14/290 (4%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQA--TLNGHIGHITCVTFSPNNLLV 1023
L ++ + + L A+G A L+ +W + RL+A TL G G IT V F P+ V
Sbjct: 259 LSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSVDFDPSGYQV 318
Query: 1024 LSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGI 1083
L+ + ++ +W++ + T GH + +A++ R R V W +
Sbjct: 319 LAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAY 378
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
+ S DV + D +R W G ++ + R+T +L+
Sbjct: 379 CSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCTQ----VIPVQGRVTSLSLS 434
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTC-----VAVSITNKTQVVSGSWD 1198
D H+++ S D +LKV L + QV +D C AV +++ ++GS D
Sbjct: 435 HDQLHLLSCSRDNTLKVIDLRVSNIRQVF--RADGFKCGSDWTKAVFSPDRSYALAGSCD 492
Query: 1199 CNLIVWDINTXXXXXXXXX-XXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
L +WD++T V V G+ VS + + +++W+
Sbjct: 493 GALYIWDVDTGKLESRLQGPHCAAVNAVAWCYSGSHMVSVDQGRKVVLWQ 542
Score = 54.0 bits (124), Expect = 4e-06
Identities = 54/262 (20%), Positives = 104/262 (39%), Gaps = 17/262 (6%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN--SPSLTYKGHSSAIQTL 1056
R Q L+ H+ + V F PN+ L+ +G DR + +W + + + T +G +I ++
Sbjct: 250 RAQDVLDAHLSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSV 309
Query: 1057 LMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVT---LNMKYAVLSDGDNSV 1113
G + +++ + +W V + +G + L AV D +V
Sbjct: 310 DFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTV 369
Query: 1114 RIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLV 1173
+ W L G +S+ + C +++G D ++ W G +QV+
Sbjct: 370 KEWDL-GRAYCSRTINVLSYCNDVVC-----GDHIIISGHNDQKIRFWDSRGPHCTQVIP 423
Query: 1174 GHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKV----TCVKVTG 1229
VT +++S ++ ++S S D L V D+ K T +
Sbjct: 424 VQGR-VTSLSLS-HDQLHLLSCSRDNTLKVIDLRVSNIRQVFRADGFKCGSDWTKAVFSP 481
Query: 1230 DGTIAVSCAEDKTLIIWETKRG 1251
D + A++ + D L IW+ G
Sbjct: 482 DRSYALAGSCDGALYIWDVDTG 503
Score = 42.3 bits (95), Expect = 0.012
Identities = 34/141 (24%), Positives = 59/141 (41%), Gaps = 4/141 (2%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVW 721
PSG ++ A QLW + T GH + +TGS D +V W
Sbjct: 313 PSGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEW 372
Query: 722 DLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSV 781
DL A ++ + ++ C + ++ISG +D + G T++ +G V
Sbjct: 373 DLGR-AYCSRTINVLS--YCNDVVCGDHIIISGHNDQKIRFWD-SRGPHCTQVIPVQGRV 428
Query: 782 TSVKVIQDGNIFITGSQDGTV 802
TS+ + D ++ S+D T+
Sbjct: 429 TSLSLSHDQLHLLSCSRDNTL 449
>AK127882-1|BAC87175.1| 369|Homo sapiens protein ( Homo sapiens cDNA
FLJ45988 fis, clone PUAEN2006639, weakly similar to
Vegetatible incompatibility protein HET-E-1. ).
Length = 369
Score = 81.8 bits (193), Expect = 2e-14
Identities = 56/250 (22%), Positives = 110/250 (44%), Gaps = 11/250 (4%)
Query: 997 THRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTL 1056
T L L HI +T V + + ++GS DRT +W A T +GH + + +
Sbjct: 81 TFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAI 140
Query: 1057 LMMSD-GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDG--DNS 1112
+ G + + + +W V++G H+ G +A I ++ N + +++ G D +
Sbjct: 141 AFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTT 200
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
++W + G+ R H+ I + ++TGS D ++ VW D G+ +L
Sbjct: 201 AKLWDIQNGEEVYTLR---GHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNIL 257
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKV--TCVKVTGD 1230
+GH ++ + + + + +++GS D +WD ++ +C TG
Sbjct: 258 IGHCAEISSASFN-WDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGK 316
Query: 1231 GTIAVSCAED 1240
IA + A+D
Sbjct: 317 -LIATASADD 325
Score = 77.4 bits (182), Expect = 4e-13
Identities = 51/236 (21%), Positives = 100/236 (42%), Gaps = 7/236 (2%)
Query: 958 LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFS 1017
L + ++ ++P++ + +++ G +G ++W ++ TL GH + + F+
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFN 143
Query: 1018 -PNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHV 1076
P + +GS D+T +W + T++GH++ I L + +
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKL 203
Query: 1077 WLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSH 1133
W + +G +++ G SA I ++ N + G D++V +W D + H
Sbjct: 204 WDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWD---ADTGRKVNILIGH 260
Query: 1134 AERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNK 1189
I+ + D ++TGSMD + K+W GK L GH D + T K
Sbjct: 261 CAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGK 316
Score = 77.0 bits (181), Expect = 5e-13
Identities = 38/141 (26%), Positives = 69/141 (48%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
+LW + + HTF+GH+ I+C+ +S + TGS DT+ +WD+ + H
Sbjct: 160 KLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHS 219
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A ++ ++ + +I+G D V++ G V L H ++S D ++ +TG
Sbjct: 220 AEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTG 279
Query: 797 SQDGTVCTWNVENFTLLSTVT 817
S D T W+ N ++T+T
Sbjct: 280 SMDKTCKLWDATNGKCVATLT 300
Score = 74.1 bits (174), Expect = 3e-12
Identities = 49/218 (22%), Positives = 96/218 (44%), Gaps = 8/218 (3%)
Query: 1047 KGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYA- 1104
K H + + + G ++ R +W SG L++ G + + N Y
Sbjct: 89 KAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPYGD 148
Query: 1105 VLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWK 1162
++ G D + ++WS+ G R H I C + S V TGSMD + K+W
Sbjct: 149 KIATGSFDKTCKLWSVETGKCYHTFR---GHTAEIVCLSFNPQSTLVATGSMDTTAKLWD 205
Query: 1163 LDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKV 1222
+ G+ L GHS + ++ + T+ ++++GS+D ++VWD +T ++
Sbjct: 206 IQNGEEVYTLRGHSAEIISLSFN-TSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEI 264
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
+ D ++ ++ + DKT +W+ G + + + H
Sbjct: 265 SSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGH 302
Score = 61.3 bits (142), Expect = 2e-08
Identities = 47/213 (22%), Positives = 83/213 (38%), Gaps = 2/213 (0%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRE-SQYLLTGSEDTSVIVWDLHTLAVKTKILEH 735
+LW S +++T +GH + + + TGS D + +W + T H
Sbjct: 117 KLWDSASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGH 176
Query: 736 IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFIT 795
A ++C++ +LV +G D+ + + +G V L H + S+ G+ IT
Sbjct: 177 TAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIIT 236
Query: 796 GSQDGTVCTWNVENFTLLSTVTAG-VPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYL 854
GS D TV W+ + ++ + I D +LT D L G +
Sbjct: 237 GSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCV 296
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYL 887
L H ++ C + +A AD + L
Sbjct: 297 ATLTGHDDEILDSCFDYTGKLIATASADDGVSL 329
Score = 58.4 bits (135), Expect = 2e-07
Identities = 35/161 (21%), Positives = 66/161 (40%), Gaps = 7/161 (4%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQ 1191
+H +T AL +TGS D + K+W G+ L GH ++V +A + +
Sbjct: 90 AHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPYGDK 149
Query: 1192 VVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ +GS+D +W + T ++ C+ T+ + + D T +W+ + G
Sbjct: 150 IATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNG 209
Query: 1252 ---LALTSFSLHVPLLGFQITSDCARVVVHLLDRGCLPIIW 1289
L S + L F + D R++ D ++W
Sbjct: 210 EEVYTLRGHSAEIISLSFNTSGD--RIITGSFDH--TVVVW 246
Score = 43.2 bits (97), Expect = 0.007
Identities = 32/128 (25%), Positives = 58/128 (45%), Gaps = 4/128 (3%)
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVF 833
L H +T+V + + G+ FITGS D T W+ + L+T+ + ++ + +N +
Sbjct: 88 LKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNV-VYAIAFNNPY 146
Query: 834 ---LLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ T D L + TG H + H A++ C S+ VA G D L+ +
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI 206
Query: 891 HSAQLLRT 898
+ + + T
Sbjct: 207 QNGEEVYT 214
Score = 40.3 bits (90), Expect = 0.050
Identities = 37/167 (22%), Positives = 60/167 (35%), Gaps = 2/167 (1%)
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTS 783
HT + + HI P+ VA + S I+G D + G + L+ HR V +
Sbjct: 80 HTFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYA 139
Query: 784 VKVIQD-GNIFITGSQDGTVCTWNVENFTLLSTVTA-GVPIHIFDVTDDNVFLLTLQGDN 841
+ G+ TGS D T W+VE T I + + T D
Sbjct: 140 IAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDT 199
Query: 842 ELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
L G ++ L+ H A++ R+ G D + ++
Sbjct: 200 TAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVW 246
Score = 37.9 bits (84), Expect = 0.26
Identities = 42/213 (19%), Positives = 82/213 (38%), Gaps = 8/213 (3%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVN--R 748
K H + + + + +TGS D + +WD + LE V+ A N
Sbjct: 89 KAHILPLTNVALNKSGSCFITGSYDRTCKLWD-SASGEELNTLEGHRNVVYAIAFNNPYG 147
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
+ +G D + S+ G H + + + TGS D T W+++
Sbjct: 148 DKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQ 207
Query: 809 NFTLLSTV---TAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVK 865
N + T+ +A + F+ + D + +T D+ + + TG ++ L H A++
Sbjct: 208 NGEEVYTLRGHSAEIISLSFNTSGDRI--ITGSFDHTVVVWDADTGRKVNILIGHCAEIS 265
Query: 866 CFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
D S + G D+ L+ + + + T
Sbjct: 266 SASFNWDCSLILTGSMDKTCKLWDATNGKCVAT 298
>X95525-1|CAA64777.1| 799|Homo sapiens hTAFII100 protein.
Length = 799
Score = 81.0 bits (191), Expect = 3e-14
Identities = 59/220 (26%), Positives = 92/220 (41%), Gaps = 7/220 (3%)
Query: 989 LVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKG 1048
L R+ T L GH G + +FSP+ +LS SED TV +W L + + YKG
Sbjct: 524 LERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKG 583
Query: 1049 HSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NMKYAV 1105
H+ + G +S R +W D L G A ++ T N Y
Sbjct: 584 HNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVA 643
Query: 1106 LSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDG 1165
D +VR+W + G+ R H I + + + + TG+ D + +W +
Sbjct: 644 TGSADRTVRLWDVLNGNCV---RIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH 700
Query: 1166 GKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
G + L GH+D V + S + + SGS D + +WD
Sbjct: 701 GLMVGELKGHTDTVCSLRFSRDGEI-LASGSMDNTVRLWD 739
Score = 70.5 bits (165), Expect = 4e-11
Identities = 62/282 (21%), Positives = 115/282 (40%), Gaps = 18/282 (6%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
++ ++V+ D L A G A VRVW ++ +L++ V + + L+ S+
Sbjct: 473 LTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRS-----------VKQASDLSLIDKESD 521
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D + S GHS + D +SS V +W + + L
Sbjct: 522 DVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGY 581
Query: 1089 TGPSASI-DVTLN-MKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
G + + D + Y +S G D R+W+ D+ + R H + C +
Sbjct: 582 KGHNYPVWDTQFSPYGYYFVSGGHDRVARLWAT---DHYQPLRIFAGHLADVNCTRFHPN 638
Query: 1146 SQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
S +V TGS D ++++W + G ++ GH + + S N + +G+ D +++WD
Sbjct: 639 SNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFS-PNGRFLATGATDGRVLLWD 697
Query: 1206 INTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
I V ++ + DG I S + D T+ +W+
Sbjct: 698 IGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
Score = 70.1 bits (164), Expect = 5e-11
Identities = 43/158 (27%), Positives = 69/158 (43%), Gaps = 1/158 (0%)
Query: 659 QLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSV 718
Q +P G + V +LW + F GH + C S Y+ TGS D +V
Sbjct: 592 QFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTV 651
Query: 719 IVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHR 778
+WD+ H P+ + N + +G D V++ + G +V +L H
Sbjct: 652 RLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHT 711
Query: 779 GSVTSVKVIQDGNIFITGSQDGTVCTWN-VENFTLLST 815
+V S++ +DG I +GS D TV W+ ++ F L T
Sbjct: 712 DTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLET 749
Score = 67.3 bits (157), Expect = 4e-10
Identities = 41/168 (24%), Positives = 74/168 (44%), Gaps = 3/168 (1%)
Query: 952 STTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHI 1011
S T L + P+ + S G SG + R+W ++ GH+ +
Sbjct: 571 SLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADV 630
Query: 1012 TCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRA 1071
C F PN+ V +GS DRTV +W + + + + GH I +L +GR +
Sbjct: 631 NCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATD 690
Query: 1072 RNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSDG--DNSVRIW 1116
V +W + G+++ G + ++ + + +L+ G DN+VR+W
Sbjct: 691 GRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
Score = 64.1 bits (149), Expect = 4e-09
Identities = 44/197 (22%), Positives = 75/197 (38%), Gaps = 6/197 (3%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
P+ S D S G VR+W L T GH + FSP +SG
Sbjct: 545 PVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGG 604
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHS 1087
DR +W P + GH + + + + R V +W V +G +
Sbjct: 605 HDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRI 664
Query: 1088 AT---GPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTA 1144
T GP S+ + N ++ D V +W + G + + H + + +
Sbjct: 665 FTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELK---GHTDTVCSLRFSR 721
Query: 1145 DSQHVVTGSMDMSLKVW 1161
D + + +GSMD ++++W
Sbjct: 722 DGEILASGSMDNTVRLW 738
Score = 63.3 bits (147), Expect = 6e-09
Identities = 60/235 (25%), Positives = 83/235 (35%), Gaps = 4/235 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFK---GHSGSILCMCVTRESQYLLTGSE 714
L+ L L D L IM K GHSG + + + YLL+ SE
Sbjct: 504 LRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSE 563
Query: 715 DTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
D +V +W L T H PV +SGG D + + +
Sbjct: 564 DGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIF 623
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVF 833
H V + + N TGS D TV W+V N + T PIH + + F
Sbjct: 624 AGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRF 683
Query: 834 LLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
L T D + L G + LK H V + D +A G D + L+
Sbjct: 684 LATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
Score = 48.4 bits (110), Expect = 2e-04
Identities = 51/213 (23%), Positives = 87/213 (40%), Gaps = 16/213 (7%)
Query: 688 HTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVN 747
+TF + + VT +S + G D++V VW + +++ V +
Sbjct: 464 YTFLNVYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRS-----------VKQASD 512
Query: 748 RSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
SL+ DD I + + L H G V D N ++ S+DGTV W++
Sbjct: 513 LSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL 572
Query: 808 ENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLK---RHKAKV 864
+ FT L G ++D + G ++ R + T Y PL+ H A V
Sbjct: 573 QTFTCLVGYK-GHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHY-QPLRIFAGHLADV 630
Query: 865 KCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
C +S+ VA G AD+ + L+ + + +R
Sbjct: 631 NCTRFHPNSNYVATGSADRTVRLWDVLNGNCVR 663
Score = 43.2 bits (97), Expect = 0.007
Identities = 20/65 (30%), Positives = 34/65 (52%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L +P+G+ L + G LW I V KGH+ ++ + +R+ + L +GS D +
Sbjct: 675 LTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNT 734
Query: 718 VIVWD 722
V +WD
Sbjct: 735 VRLWD 739
>U80191-1|AAC51215.1| 800|Homo sapiens TFIID subunit TAFII100
protein.
Length = 800
Score = 81.0 bits (191), Expect = 3e-14
Identities = 59/220 (26%), Positives = 92/220 (41%), Gaps = 7/220 (3%)
Query: 989 LVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKG 1048
L R+ T L GH G + +FSP+ +LS SED TV +W L + + YKG
Sbjct: 524 LERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKG 583
Query: 1049 HSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NMKYAV 1105
H+ + G +S R +W D L G A ++ T N Y
Sbjct: 584 HNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVA 643
Query: 1106 LSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDG 1165
D +VR+W + G+ R H I + + + + TG+ D + +W +
Sbjct: 644 TGSADRTVRLWDVLNGNCV---RIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH 700
Query: 1166 GKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
G + L GH+D V + S + + SGS D + +WD
Sbjct: 701 GLMVGELKGHTDTVCSLRFSRDGEI-LASGSMDNTVRLWD 739
Score = 70.9 bits (166), Expect = 3e-11
Identities = 71/320 (22%), Positives = 128/320 (40%), Gaps = 25/320 (7%)
Query: 934 DNLTNFRPTKQMKRRQTKSTTNI---TLLQAEQSDLIPISCLEVSRDGQLGASGCARGLV 990
D + N + T + R +I T L A Q ++ ++V+ D L A G A V
Sbjct: 439 DKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQG----LTAVDVTDDSSLIAGGFADSTV 494
Query: 991 RVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
RVW ++ +L++ V + + L+ S+D + S GHS
Sbjct: 495 RVWSVTPKKLRS-----------VKQASDLSLIDKESDDVLERIMDEKTASELKILYGHS 543
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLN-MKYAVLSD 1108
+ D +SS V +W + + L G + + D + Y +S
Sbjct: 544 GPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSG 603
Query: 1109 G-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK 1167
G D R+W+ D+ + R H + C +S +V TGS D ++++W + G
Sbjct: 604 GHDRVARLWAT---DHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN 660
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV 1227
++ GH + + S N + +G+ D +++WDI V ++
Sbjct: 661 CVRIFTGHKGPIHSLTFS-PNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 719
Query: 1228 TGDGTIAVSCAEDKTLIIWE 1247
+ DG I S + D T+ +W+
Sbjct: 720 SRDGEILASGSMDNTVRLWD 739
Score = 70.1 bits (164), Expect = 5e-11
Identities = 43/158 (27%), Positives = 69/158 (43%), Gaps = 1/158 (0%)
Query: 659 QLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSV 718
Q +P G + V +LW + F GH + C S Y+ TGS D +V
Sbjct: 592 QFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTV 651
Query: 719 IVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHR 778
+WD+ H P+ + N + +G D V++ + G +V +L H
Sbjct: 652 RLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHT 711
Query: 779 GSVTSVKVIQDGNIFITGSQDGTVCTWN-VENFTLLST 815
+V S++ +DG I +GS D TV W+ ++ F L T
Sbjct: 712 DTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLET 749
Score = 63.3 bits (147), Expect = 6e-09
Identities = 60/235 (25%), Positives = 83/235 (35%), Gaps = 4/235 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFK---GHSGSILCMCVTRESQYLLTGSE 714
L+ L L D L IM K GHSG + + + YLL+ SE
Sbjct: 504 LRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSE 563
Query: 715 DTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
D +V +W L T H PV +SGG D + + +
Sbjct: 564 DGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIF 623
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVF 833
H V + + N TGS D TV W+V N + T PIH + + F
Sbjct: 624 AGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRF 683
Query: 834 LLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
L T D + L G + LK H V + D +A G D + L+
Sbjct: 684 LATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
Score = 48.8 bits (111), Expect = 1e-04
Identities = 51/213 (23%), Positives = 87/213 (40%), Gaps = 16/213 (7%)
Query: 688 HTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVN 747
+TF + + VT +S + G D++V VW + +++ V +
Sbjct: 464 YTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRS-----------VKQASD 512
Query: 748 RSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
SL+ DD I + + L H G V D N ++ S+DGTV W++
Sbjct: 513 LSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL 572
Query: 808 ENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLK---RHKAKV 864
+ FT L G ++D + G ++ R + T Y PL+ H A V
Sbjct: 573 QTFTCLVGYK-GHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHY-QPLRIFAGHLADV 630
Query: 865 KCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
C +S+ VA G AD+ + L+ + + +R
Sbjct: 631 NCTRFHPNSNYVATGSADRTVRLWDVLNGNCVR 663
Score = 43.2 bits (97), Expect = 0.007
Identities = 20/65 (30%), Positives = 34/65 (52%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L +P+G+ L + G LW I V KGH+ ++ + +R+ + L +GS D +
Sbjct: 675 LTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNT 734
Query: 718 VIVWD 722
V +WD
Sbjct: 735 VRLWD 739
>U75309-1|AAC50902.1| 801|Homo sapiens TBP-associated factor protein.
Length = 801
Score = 81.0 bits (191), Expect = 3e-14
Identities = 59/220 (26%), Positives = 92/220 (41%), Gaps = 7/220 (3%)
Query: 989 LVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKG 1048
L R+ T L GH G + +FSP+ +LS SED TV +W L + + YKG
Sbjct: 525 LERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKG 584
Query: 1049 HSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NMKYAV 1105
H+ + G +S R +W D L G A ++ T N Y
Sbjct: 585 HNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVA 644
Query: 1106 LSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDG 1165
D +VR+W + G+ R H I + + + + TG+ D + +W +
Sbjct: 645 TGSADRTVRLWDVLNGNCV---RIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH 701
Query: 1166 GKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
G + L GH+D V + S + + SGS D + +WD
Sbjct: 702 GLMVGELKGHTDTVCSLRFSRDGEI-LASGSMDNTVRLWD 740
Score = 70.9 bits (166), Expect = 3e-11
Identities = 71/320 (22%), Positives = 128/320 (40%), Gaps = 25/320 (7%)
Query: 934 DNLTNFRPTKQMKRRQTKSTTNI---TLLQAEQSDLIPISCLEVSRDGQLGASGCARGLV 990
D + N + T + R +I T L A Q ++ ++V+ D L A G A V
Sbjct: 440 DKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQG----LTAVDVTDDSSLIAGGFADSTV 495
Query: 991 RVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
RVW ++ +L++ V + + L+ S+D + S GHS
Sbjct: 496 RVWSVTPKKLRS-----------VKQASDLSLIDKESDDVLERIMDEKTASELKILYGHS 544
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLN-MKYAVLSD 1108
+ D +SS V +W + + L G + + D + Y +S
Sbjct: 545 GPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSG 604
Query: 1109 G-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK 1167
G D R+W+ D+ + R H + C +S +V TGS D ++++W + G
Sbjct: 605 GHDRVARLWAT---DHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN 661
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV 1227
++ GH + + S N + +G+ D +++WDI V ++
Sbjct: 662 CVRIFTGHKGPIHSLTFS-PNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 720
Query: 1228 TGDGTIAVSCAEDKTLIIWE 1247
+ DG I S + D T+ +W+
Sbjct: 721 SRDGEILASGSMDNTVRLWD 740
Score = 70.1 bits (164), Expect = 5e-11
Identities = 43/158 (27%), Positives = 69/158 (43%), Gaps = 1/158 (0%)
Query: 659 QLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSV 718
Q +P G + V +LW + F GH + C S Y+ TGS D +V
Sbjct: 593 QFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTV 652
Query: 719 IVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHR 778
+WD+ H P+ + N + +G D V++ + G +V +L H
Sbjct: 653 RLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHT 712
Query: 779 GSVTSVKVIQDGNIFITGSQDGTVCTWN-VENFTLLST 815
+V S++ +DG I +GS D TV W+ ++ F L T
Sbjct: 713 DTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLET 750
Score = 63.3 bits (147), Expect = 6e-09
Identities = 60/235 (25%), Positives = 83/235 (35%), Gaps = 4/235 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFK---GHSGSILCMCVTRESQYLLTGSE 714
L+ L L D L IM K GHSG + + + YLL+ SE
Sbjct: 505 LRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSE 564
Query: 715 DTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
D +V +W L T H PV +SGG D + + +
Sbjct: 565 DGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIF 624
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVF 833
H V + + N TGS D TV W+V N + T PIH + + F
Sbjct: 625 AGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRF 684
Query: 834 LLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
L T D + L G + LK H V + D +A G D + L+
Sbjct: 685 LATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 739
Score = 48.8 bits (111), Expect = 1e-04
Identities = 51/213 (23%), Positives = 87/213 (40%), Gaps = 16/213 (7%)
Query: 688 HTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVN 747
+TF + + VT +S + G D++V VW + +++ V +
Sbjct: 465 YTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRS-----------VKQASD 513
Query: 748 RSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
SL+ DD I + + L H G V D N ++ S+DGTV W++
Sbjct: 514 LSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL 573
Query: 808 ENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLK---RHKAKV 864
+ FT L G ++D + G ++ R + T Y PL+ H A V
Sbjct: 574 QTFTCLVGYK-GHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHY-QPLRIFAGHLADV 631
Query: 865 KCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
C +S+ VA G AD+ + L+ + + +R
Sbjct: 632 NCTRFHPNSNYVATGSADRTVRLWDVLNGNCVR 664
Score = 43.2 bits (97), Expect = 0.007
Identities = 20/65 (30%), Positives = 34/65 (52%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L +P+G+ L + G LW I V KGH+ ++ + +R+ + L +GS D +
Sbjct: 676 LTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNT 735
Query: 718 VIVWD 722
V +WD
Sbjct: 736 VRLWD 740
>BC052268-1|AAH52268.2| 800|Homo sapiens TAF5 RNA polymerase II, TATA
box binding protein (TBP)-associated factor, 100kD
protein.
Length = 800
Score = 81.0 bits (191), Expect = 3e-14
Identities = 59/220 (26%), Positives = 92/220 (41%), Gaps = 7/220 (3%)
Query: 989 LVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKG 1048
L R+ T L GH G + +FSP+ +LS SED TV +W L + + YKG
Sbjct: 524 LERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKG 583
Query: 1049 HSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NMKYAV 1105
H+ + G +S R +W D L G A ++ T N Y
Sbjct: 584 HNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVA 643
Query: 1106 LSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDG 1165
D +VR+W + G+ R H I + + + + TG+ D + +W +
Sbjct: 644 TGSADRTVRLWDVLNGNCV---RIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH 700
Query: 1166 GKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
G + L GH+D V + S + + SGS D + +WD
Sbjct: 701 GLMVGELKGHTDTVCSLRFSRDGEI-LASGSMDNTVRLWD 739
Score = 70.9 bits (166), Expect = 3e-11
Identities = 71/320 (22%), Positives = 128/320 (40%), Gaps = 25/320 (7%)
Query: 934 DNLTNFRPTKQMKRRQTKSTTNI---TLLQAEQSDLIPISCLEVSRDGQLGASGCARGLV 990
D + N + T + R +I T L A Q ++ ++V+ D L A G A V
Sbjct: 439 DKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQG----LTAVDVTDDSSLIAGGFADSTV 494
Query: 991 RVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
RVW ++ +L++ V + + L+ S+D + S GHS
Sbjct: 495 RVWSVTPKKLRS-----------VKQASDLSLIDKESDDVLERIMDEKTASELKILYGHS 543
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLN-MKYAVLSD 1108
+ D +SS V +W + + L G + + D + Y +S
Sbjct: 544 GPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSG 603
Query: 1109 G-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK 1167
G D R+W+ D+ + R H + C +S +V TGS D ++++W + G
Sbjct: 604 GHDRVARLWAT---DHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN 660
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV 1227
++ GH + + S N + +G+ D +++WDI V ++
Sbjct: 661 CVRIFTGHKGPIHSLTFS-PNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 719
Query: 1228 TGDGTIAVSCAEDKTLIIWE 1247
+ DG I S + D T+ +W+
Sbjct: 720 SRDGEILASGSMDNTVRLWD 739
Score = 70.1 bits (164), Expect = 5e-11
Identities = 43/158 (27%), Positives = 69/158 (43%), Gaps = 1/158 (0%)
Query: 659 QLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSV 718
Q +P G + V +LW + F GH + C S Y+ TGS D +V
Sbjct: 592 QFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTV 651
Query: 719 IVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHR 778
+WD+ H P+ + N + +G D V++ + G +V +L H
Sbjct: 652 RLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHT 711
Query: 779 GSVTSVKVIQDGNIFITGSQDGTVCTWN-VENFTLLST 815
+V S++ +DG I +GS D TV W+ ++ F L T
Sbjct: 712 DTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLET 749
Score = 63.3 bits (147), Expect = 6e-09
Identities = 60/235 (25%), Positives = 83/235 (35%), Gaps = 4/235 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFK---GHSGSILCMCVTRESQYLLTGSE 714
L+ L L D L IM K GHSG + + + YLL+ SE
Sbjct: 504 LRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSE 563
Query: 715 DTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
D +V +W L T H PV +SGG D + + +
Sbjct: 564 DGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIF 623
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVF 833
H V + + N TGS D TV W+V N + T PIH + + F
Sbjct: 624 AGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRF 683
Query: 834 LLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
L T D + L G + LK H V + D +A G D + L+
Sbjct: 684 LATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
Score = 48.8 bits (111), Expect = 1e-04
Identities = 51/213 (23%), Positives = 87/213 (40%), Gaps = 16/213 (7%)
Query: 688 HTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVN 747
+TF + + VT +S + G D++V VW + +++ V +
Sbjct: 464 YTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRS-----------VKQASD 512
Query: 748 RSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
SL+ DD I + + L H G V D N ++ S+DGTV W++
Sbjct: 513 LSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL 572
Query: 808 ENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLK---RHKAKV 864
+ FT L G ++D + G ++ R + T Y PL+ H A V
Sbjct: 573 QTFTCLVGYK-GHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHY-QPLRIFAGHLADV 630
Query: 865 KCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
C +S+ VA G AD+ + L+ + + +R
Sbjct: 631 NCTRFHPNSNYVATGSADRTVRLWDVLNGNCVR 663
Score = 43.2 bits (97), Expect = 0.007
Identities = 20/65 (30%), Positives = 34/65 (52%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L +P+G+ L + G LW I V KGH+ ++ + +R+ + L +GS D +
Sbjct: 675 LTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNT 734
Query: 718 VIVWD 722
V +WD
Sbjct: 735 VRLWD 739
>AL591408-4|CAI16747.1| 800|Homo sapiens TAF5 RNA polymerase II, TATA
box binding protein (TBP)-associated factor, 100kD
protein.
Length = 800
Score = 81.0 bits (191), Expect = 3e-14
Identities = 59/220 (26%), Positives = 92/220 (41%), Gaps = 7/220 (3%)
Query: 989 LVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKG 1048
L R+ T L GH G + +FSP+ +LS SED TV +W L + + YKG
Sbjct: 524 LERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKG 583
Query: 1049 HSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NMKYAV 1105
H+ + G +S R +W D L G A ++ T N Y
Sbjct: 584 HNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVA 643
Query: 1106 LSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDG 1165
D +VR+W + G+ R H I + + + + TG+ D + +W +
Sbjct: 644 TGSADRTVRLWDVLNGNCV---RIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH 700
Query: 1166 GKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
G + L GH+D V + S + + SGS D + +WD
Sbjct: 701 GLMVGELKGHTDTVCSLRFSRDGEI-LASGSMDNTVRLWD 739
Score = 70.9 bits (166), Expect = 3e-11
Identities = 71/320 (22%), Positives = 128/320 (40%), Gaps = 25/320 (7%)
Query: 934 DNLTNFRPTKQMKRRQTKSTTNI---TLLQAEQSDLIPISCLEVSRDGQLGASGCARGLV 990
D + N + T + R +I T L A Q ++ ++V+ D L A G A V
Sbjct: 439 DKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQG----LTAVDVTDDSSLIAGGFADSTV 494
Query: 991 RVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
RVW ++ +L++ V + + L+ S+D + S GHS
Sbjct: 495 RVWSVTPKKLRS-----------VKQASDLSLIDKESDDVLERIMDEKTASELKILYGHS 543
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLN-MKYAVLSD 1108
+ D +SS V +W + + L G + + D + Y +S
Sbjct: 544 GPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSG 603
Query: 1109 G-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK 1167
G D R+W+ D+ + R H + C +S +V TGS D ++++W + G
Sbjct: 604 GHDRVARLWAT---DHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN 660
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV 1227
++ GH + + S N + +G+ D +++WDI V ++
Sbjct: 661 CVRIFTGHKGPIHSLTFS-PNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 719
Query: 1228 TGDGTIAVSCAEDKTLIIWE 1247
+ DG I S + D T+ +W+
Sbjct: 720 SRDGEILASGSMDNTVRLWD 739
Score = 70.1 bits (164), Expect = 5e-11
Identities = 43/158 (27%), Positives = 69/158 (43%), Gaps = 1/158 (0%)
Query: 659 QLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSV 718
Q +P G + V +LW + F GH + C S Y+ TGS D +V
Sbjct: 592 QFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTV 651
Query: 719 IVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHR 778
+WD+ H P+ + N + +G D V++ + G +V +L H
Sbjct: 652 RLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHT 711
Query: 779 GSVTSVKVIQDGNIFITGSQDGTVCTWN-VENFTLLST 815
+V S++ +DG I +GS D TV W+ ++ F L T
Sbjct: 712 DTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLET 749
Score = 63.3 bits (147), Expect = 6e-09
Identities = 60/235 (25%), Positives = 83/235 (35%), Gaps = 4/235 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFK---GHSGSILCMCVTRESQYLLTGSE 714
L+ L L D L IM K GHSG + + + YLL+ SE
Sbjct: 504 LRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSE 563
Query: 715 DTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
D +V +W L T H PV +SGG D + + +
Sbjct: 564 DGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIF 623
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVF 833
H V + + N TGS D TV W+V N + T PIH + + F
Sbjct: 624 AGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRF 683
Query: 834 LLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
L T D + L G + LK H V + D +A G D + L+
Sbjct: 684 LATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
Score = 48.8 bits (111), Expect = 1e-04
Identities = 51/213 (23%), Positives = 87/213 (40%), Gaps = 16/213 (7%)
Query: 688 HTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVN 747
+TF + + VT +S + G D++V VW + +++ V +
Sbjct: 464 YTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRS-----------VKQASD 512
Query: 748 RSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
SL+ DD I + + L H G V D N ++ S+DGTV W++
Sbjct: 513 LSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL 572
Query: 808 ENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLK---RHKAKV 864
+ FT L G ++D + G ++ R + T Y PL+ H A V
Sbjct: 573 QTFTCLVGYK-GHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHY-QPLRIFAGHLADV 630
Query: 865 KCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
C +S+ VA G AD+ + L+ + + +R
Sbjct: 631 NCTRFHPNSNYVATGSADRTVRLWDVLNGNCVR 663
Score = 43.2 bits (97), Expect = 0.007
Identities = 20/65 (30%), Positives = 34/65 (52%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L +P+G+ L + G LW I V KGH+ ++ + +R+ + L +GS D +
Sbjct: 675 LTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNT 734
Query: 718 VIVWD 722
V +WD
Sbjct: 735 VRLWD 739
>AK223615-1|BAD97335.1| 803|Homo sapiens Transcription initiation
factor TFIID subunit 5 variant protein.
Length = 803
Score = 81.0 bits (191), Expect = 3e-14
Identities = 59/220 (26%), Positives = 92/220 (41%), Gaps = 7/220 (3%)
Query: 989 LVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKG 1048
L R+ T L GH G + +FSP+ +LS SED TV +W L + + YKG
Sbjct: 527 LERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKG 586
Query: 1049 HSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NMKYAV 1105
H+ + G +S R +W D L G A ++ T N Y
Sbjct: 587 HNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVA 646
Query: 1106 LSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDG 1165
D +VR+W + G+ R H I + + + + TG+ D + +W +
Sbjct: 647 TGSADRTVRLWDVLNGNCV---RIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH 703
Query: 1166 GKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
G + L GH+D V + S + + SGS D + +WD
Sbjct: 704 GLMVGELKGHTDTVCSLRFSRDGEI-LASGSMDNTVRLWD 742
Score = 70.9 bits (166), Expect = 3e-11
Identities = 71/320 (22%), Positives = 128/320 (40%), Gaps = 25/320 (7%)
Query: 934 DNLTNFRPTKQMKRRQTKSTTNI---TLLQAEQSDLIPISCLEVSRDGQLGASGCARGLV 990
D + N + T + R +I T L A Q ++ ++V+ D L A G A V
Sbjct: 442 DKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQG----LTAVDVTDDSSLIAGGFADSTV 497
Query: 991 RVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
RVW ++ +L++ V + + L+ S+D + S GHS
Sbjct: 498 RVWSVTPKKLRS-----------VKQASDLSLIDKESDDVLERIMDEKTASELKILYGHS 546
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLN-MKYAVLSD 1108
+ D +SS V +W + + L G + + D + Y +S
Sbjct: 547 GPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSG 606
Query: 1109 G-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK 1167
G D R+W+ D+ + R H + C +S +V TGS D ++++W + G
Sbjct: 607 GHDRVARLWAT---DHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN 663
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV 1227
++ GH + + S N + +G+ D +++WDI V ++
Sbjct: 664 CVRIFTGHKGPIHSLTFS-PNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 722
Query: 1228 TGDGTIAVSCAEDKTLIIWE 1247
+ DG I S + D T+ +W+
Sbjct: 723 SRDGEILASGSMDNTVRLWD 742
Score = 70.1 bits (164), Expect = 5e-11
Identities = 43/158 (27%), Positives = 69/158 (43%), Gaps = 1/158 (0%)
Query: 659 QLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSV 718
Q +P G + V +LW + F GH + C S Y+ TGS D +V
Sbjct: 595 QFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTV 654
Query: 719 IVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHR 778
+WD+ H P+ + N + +G D V++ + G +V +L H
Sbjct: 655 RLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHT 714
Query: 779 GSVTSVKVIQDGNIFITGSQDGTVCTWN-VENFTLLST 815
+V S++ +DG I +GS D TV W+ ++ F L T
Sbjct: 715 DTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLET 752
Score = 63.3 bits (147), Expect = 6e-09
Identities = 60/235 (25%), Positives = 83/235 (35%), Gaps = 4/235 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFK---GHSGSILCMCVTRESQYLLTGSE 714
L+ L L D L IM K GHSG + + + YLL+ SE
Sbjct: 507 LRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSE 566
Query: 715 DTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
D +V +W L T H PV +SGG D + + +
Sbjct: 567 DGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIF 626
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVF 833
H V + + N TGS D TV W+V N + T PIH + + F
Sbjct: 627 AGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRF 686
Query: 834 LLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
L T D + L G + LK H V + D +A G D + L+
Sbjct: 687 LATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 741
Score = 48.8 bits (111), Expect = 1e-04
Identities = 51/213 (23%), Positives = 87/213 (40%), Gaps = 16/213 (7%)
Query: 688 HTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVN 747
+TF + + VT +S + G D++V VW + +++ V +
Sbjct: 467 YTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRS-----------VKQASD 515
Query: 748 RSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
SL+ DD I + + L H G V D N ++ S+DGTV W++
Sbjct: 516 LSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL 575
Query: 808 ENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLK---RHKAKV 864
+ FT L G ++D + G ++ R + T Y PL+ H A V
Sbjct: 576 QTFTCLVGYK-GHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHY-QPLRIFAGHLADV 633
Query: 865 KCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
C +S+ VA G AD+ + L+ + + +R
Sbjct: 634 NCTRFHPNSNYVATGSADRTVRLWDVLNGNCVR 666
Score = 43.2 bits (97), Expect = 0.007
Identities = 20/65 (30%), Positives = 34/65 (52%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L +P+G+ L + G LW I V KGH+ ++ + +R+ + L +GS D +
Sbjct: 678 LTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNT 737
Query: 718 VIVWD 722
V +WD
Sbjct: 738 VRLWD 742
>AK090597-1|BAC03485.1| 513|Homo sapiens protein ( Homo sapiens cDNA
FLJ33278 fis, clone ASTRO2008508, weakly similar to TIPD
PROTEIN. ).
Length = 513
Score = 81.0 bits (191), Expect = 3e-14
Identities = 67/290 (23%), Positives = 120/290 (41%), Gaps = 14/290 (4%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQA--TLNGHIGHITCVTFSPNNLLV 1023
L ++ + + L A+G A L+ +W + RL+A TL G G IT V F P+ V
Sbjct: 230 LSEVNAVGFGPNSSLLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSVDFDPSGYQV 289
Query: 1024 LSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGI 1083
L+ + ++ +W++ + T GH + +A++ R R V W +
Sbjct: 290 LAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAY 349
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
+ S DV + D +R W G ++ + R+T +L+
Sbjct: 350 CSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCTQ----VIPVQGRVTSLSLS 405
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTC-----VAVSITNKTQVVSGSWD 1198
D H+++ S D +LKV L + QV +D C AV +++ ++GS D
Sbjct: 406 HDQLHLLSCSRDNTLKVIDLRVSNIRQVF--RADGFKCGSDWTKAVFSPDRSYALAGSCD 463
Query: 1199 CNLIVWDINTXXXXXXXXX-XXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
L +WD++T V V G+ VS + + +++W+
Sbjct: 464 GALYIWDVDTGKLESRLQGPHCAAVNAVAWCYSGSHMVSVDQGRKVVLWQ 513
Score = 53.6 bits (123), Expect = 5e-06
Identities = 54/262 (20%), Positives = 104/262 (39%), Gaps = 17/262 (6%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN--SPSLTYKGHSSAIQTL 1056
R Q L+ H+ + V F PN+ L+ +G DR + +W + + + T +G +I ++
Sbjct: 221 RAQDVLDAHLSEVNAVGFGPNSSLLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSV 280
Query: 1057 LMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVT---LNMKYAVLSDGDNSV 1113
G + +++ + +W V + +G + L AV D +V
Sbjct: 281 DFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTV 340
Query: 1114 RIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLV 1173
+ W L G +S+ + C +++G D ++ W G +QV+
Sbjct: 341 KEWDL-GRAYCSRTINVLSYCNDVVC-----GDHIIISGHNDQKIRFWDSRGPHCTQVIP 394
Query: 1174 GHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKV----TCVKVTG 1229
VT +++S ++ ++S S D L V D+ K T +
Sbjct: 395 VQGR-VTSLSLS-HDQLHLLSCSRDNTLKVIDLRVSNIRQVFRADGFKCGSDWTKAVFSP 452
Query: 1230 DGTIAVSCAEDKTLIIWETKRG 1251
D + A++ + D L IW+ G
Sbjct: 453 DRSYALAGSCDGALYIWDVDTG 474
Score = 42.3 bits (95), Expect = 0.012
Identities = 34/141 (24%), Positives = 59/141 (41%), Gaps = 4/141 (2%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVW 721
PSG ++ A QLW + T GH + +TGS D +V W
Sbjct: 284 PSGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEW 343
Query: 722 DLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSV 781
DL A ++ + ++ C + ++ISG +D + G T++ +G V
Sbjct: 344 DLGR-AYCSRTINVLS--YCNDVVCGDHIIISGHNDQKIRFWD-SRGPHCTQVIPVQGRV 399
Query: 782 TSVKVIQDGNIFITGSQDGTV 802
TS+ + D ++ S+D T+
Sbjct: 400 TSLSLSHDQLHLLSCSRDNTL 420
>M36429-1|AAA63264.1| 340|Homo sapiens protein ( Human transducin
beta-2 subunit mRNA, complete cds. ).
Length = 340
Score = 80.6 bits (190), Expect = 4e-14
Identities = 58/238 (24%), Positives = 106/238 (44%), Gaps = 16/238 (6%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N ++ S S D T
Sbjct: 109 GNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + ++ + GHS + +L + DGR +S ++ +W V + + G +
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES 227
Query: 1094 SIDVTLNMK--YAVLSDGDNSV-RIWSLAGGDNSEDNRRSVSHAE---RITCFALTADSQ 1147
I+ YA + D++ R++ L ++ SH IT A + +
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDL----RADQELLMYSHDNIICGITSVAFSRSGR 283
Query: 1148 HVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
++ G D + +W G + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 284 LLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 340
Score = 65.7 bits (153), Expect = 1e-09
Identities = 48/198 (24%), Positives = 81/198 (40%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + GH G + ++ +P+ +SG+
Sbjct: 146 LSCCRFLDDNQIITSS-GDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR--RAMSSDRARNVHVWLVDSGIVLH 1086
D ++ +W + D+ T+ GH S I + +G S D + D ++++
Sbjct: 205 DASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V + +L G D + IW GD + H R++C +T
Sbjct: 265 SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 322 DDGMAVATGSWDSFLKIW 339
Score = 60.1 bits (139), Expect = 6e-08
Identities = 52/261 (19%), Positives = 101/261 (38%), Gaps = 12/261 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSATGPSASIDVT----LNMKYAVLSDGDNS 1112
G D +++ G V S P + ++ L+ + S GD +
Sbjct: 106 APSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + G + H+ + +L D + V+G+ D S+K+W + Q
Sbjct: 166 CALWDIETGQQTVG---FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
+GH + VA N +GS D ++D+ +T V +
Sbjct: 223 IGHESDINAVAF-FPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRS 281
Query: 1231 GTIAVSCAEDKTLIIWETKRG 1251
G + ++ +D IW+ +G
Sbjct: 282 GRLLLAGYDDFNCNIWDAMKG 302
Score = 56.8 bits (131), Expect = 5e-07
Identities = 45/201 (22%), Positives = 81/201 (40%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T H V+ ++ +
Sbjct: 141 GHTGYLSC-CRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NF 810
+SG D+++ + + D H + +V +G F TGS D T +++ +
Sbjct: 200 VSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQ 259
Query: 811 TLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
LL + I V L L G ++ + + + G L H +V C
Sbjct: 260 ELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLKIWN 340
Score = 55.2 bits (127), Expect = 2e-06
Identities = 44/180 (24%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Query: 672 SAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK 729
S+GD LW I + + F GHSG ++ + + + + ++G+ D S+ +WD+ +
Sbjct: 160 SSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCR 219
Query: 730 TKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSVKVI 787
+ H + + VA N +G DD+ + L D L+ D+ +TSV
Sbjct: 220 QTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFS 279
Query: 788 QDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNELHL 845
+ G + + G D W+ + V AG + VTDD + + T D+ L +
Sbjct: 280 RSGRLLLAGYDDFNCNIWDAMKGD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 338
Score = 53.2 bits (122), Expect = 7e-06
Identities = 59/292 (20%), Positives = 117/292 (40%), Gaps = 18/292 (6%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNFVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDT-TCALWDIE 172
Query: 1081 SG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+G + +G S+ + + + V D S+++W + +S + + H I
Sbjct: 173 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVR---DSMCRQTFIGHESDI 229
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVS 1194
A + TGS D + +++ L + ++ H +I+ T VA S + + +++
Sbjct: 230 NAVAFFPNGYAFTTGSDDATCRLFDLRADQ-ELLMYSHDNIICGITSVAFSRSGRL-LLA 287
Query: 1195 GSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
G D N +WD +V+C+ VT DG + + D L IW
Sbjct: 288 GYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 51.6 bits (118), Expect = 2e-05
Identities = 43/218 (19%), Positives = 93/218 (42%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
+ DN I+SL + N +R H ++C D+Q ++T S D + +
Sbjct: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ G+ + GHS V ++++ +T VSG+ D ++ +WD+
Sbjct: 169 WDIETGQQTVGFAGHSGDVMSLSLAPDGRT-FVSGACDASIKLWDVRDSMCRQTFIGHES 227
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ V +G + ++D T +++ + L +S
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYS 265
Score = 51.6 bits (118), Expect = 2e-05
Identities = 41/152 (26%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP G+ V +LW + + TF GH I + TGS+D +
Sbjct: 190 LSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDAT 249
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + + H I + VA + L+++G DD I + G L
Sbjct: 250 CRLFDLRA-DQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVL 308
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 50.0 bits (114), Expect = 6e-05
Identities = 31/147 (21%), Positives = 60/147 (40%), Gaps = 5/147 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +KVH S ++ ++ G D ++ L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + ++ S GD + + + G H G V
Sbjct: 130 EGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCA-LWDIETGQQTVGFAGHSGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVEN 809
S+ + DG F++G+ D ++ W+V +
Sbjct: 189 SLSLAPDGRTFVSGACDASIKLWDVRD 215
Score = 48.0 bits (109), Expect = 2e-04
Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 5/124 (4%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I SL +G + +L H G ++ + + D I IT S D T
Sbjct: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQI-ITSSGDTTCAL 168
Query: 805 WNVE 808
W++E
Sbjct: 169 WDIE 172
Score = 46.8 bits (106), Expect = 6e-04
Identities = 34/154 (22%), Positives = 62/154 (40%), Gaps = 5/154 (3%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ L ++ DG+ SG +++W + + T GH I V F PN +GS+
Sbjct: 187 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSD 246
Query: 1029 DRTVVVWQLADNSPSLTYKGHS--SAIQTLLMMSDGRRAMSSDRARNVHVWLV---DSGI 1083
D T ++ L + L Y + I ++ GR ++ N ++W D
Sbjct: 247 DATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAG 306
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
VL + + VT + D+ ++IW+
Sbjct: 307 VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 44.8 bits (101), Expect = 0.002
Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 101 MTC-AYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDN--QI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
++ S D +WDI T V + + DG VS A D ++ +W+ + +
Sbjct: 158 ITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSM 217
Query: 1253 ALTSFSLH 1260
+F H
Sbjct: 218 CRQTFIGH 225
Score = 38.3 bits (85), Expect = 0.20
Identities = 55/306 (17%), Positives = 103/306 (33%), Gaps = 25/306 (8%)
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H+A + + + L++S D +II V + V + GN
Sbjct: 54 HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVA 113
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVT-----DDNVFLLTLQGDNELHLRTFI 849
G D ++++ V+ +P H ++ DDN ++T GD L
Sbjct: 114 CGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCALWDIE 172
Query: 850 TGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXX 909
TG H V +A D G D I L+ + + +T
Sbjct: 173 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAV 232
Query: 910 XXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPI 969
+ G + T F + R +++ L+ + + + I
Sbjct: 233 AFFPNGYAFTTGSDDATCRLF-------DLRADQEL------------LMYSHDNIICGI 273
Query: 970 SCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSED 1029
+ + SR G+L +G +W L GH ++C+ + + + V +GS D
Sbjct: 274 TSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
Query: 1030 RTVVVW 1035
+ +W
Sbjct: 334 SFLKIW 339
>M16514-1|AAA03179.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 80.6 bits (190), Expect = 4e-14
Identities = 58/238 (24%), Positives = 106/238 (44%), Gaps = 16/238 (6%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N ++ S S D T
Sbjct: 109 GNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + ++ + GHS + +L + DGR +S ++ +W V + + G +
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES 227
Query: 1094 SIDVTLNMK--YAVLSDGDNSV-RIWSLAGGDNSEDNRRSVSHAE---RITCFALTADSQ 1147
I+ YA + D++ R++ L ++ SH IT A + +
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDL----RADQELLMYSHDNIICGITSVAFSRSGR 283
Query: 1148 HVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
++ G D + +W G + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 284 LLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 340
Score = 65.7 bits (153), Expect = 1e-09
Identities = 48/198 (24%), Positives = 81/198 (40%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + GH G + ++ +P+ +SG+
Sbjct: 146 LSCCRFLDDNQIITSS-GDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR--RAMSSDRARNVHVWLVDSGIVLH 1086
D ++ +W + D+ T+ GH S I + +G S D + D ++++
Sbjct: 205 DASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V + +L G D + IW GD + H R++C +T
Sbjct: 265 SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 322 DDGMAVATGSWDSFLKIW 339
Score = 60.1 bits (139), Expect = 6e-08
Identities = 52/261 (19%), Positives = 101/261 (38%), Gaps = 12/261 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSATGPSASIDVT----LNMKYAVLSDGDNS 1112
G D +++ G V S P + ++ L+ + S GD +
Sbjct: 106 APSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + G + H+ + +L D + V+G+ D S+K+W + Q
Sbjct: 166 CALWDIETGQQTVG---FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
+GH + VA N +GS D ++D+ +T V +
Sbjct: 223 IGHESDINAVAF-FPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRS 281
Query: 1231 GTIAVSCAEDKTLIIWETKRG 1251
G + ++ +D IW+ +G
Sbjct: 282 GRLLLAGYDDFNCNIWDAMKG 302
Score = 56.8 bits (131), Expect = 5e-07
Identities = 45/201 (22%), Positives = 81/201 (40%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T H V+ ++ +
Sbjct: 141 GHTGYLSC-CRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NF 810
+SG D+++ + + D H + +V +G F TGS D T +++ +
Sbjct: 200 VSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQ 259
Query: 811 TLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
LL + I V L L G ++ + + + G L H +V C
Sbjct: 260 ELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLKIWN 340
Score = 55.2 bits (127), Expect = 2e-06
Identities = 44/180 (24%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Query: 672 SAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK 729
S+GD LW I + + F GHSG ++ + + + + ++G+ D S+ +WD+ +
Sbjct: 160 SSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCR 219
Query: 730 TKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSVKVI 787
+ H + + VA N +G DD+ + L D L+ D+ +TSV
Sbjct: 220 QTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFS 279
Query: 788 QDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNELHL 845
+ G + + G D W+ + V AG + VTDD + + T D+ L +
Sbjct: 280 RSGRLLLAGYDDFNCNIWDAMKGD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 338
Score = 53.2 bits (122), Expect = 7e-06
Identities = 59/292 (20%), Positives = 117/292 (40%), Gaps = 18/292 (6%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNFVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDT-TCALWDIE 172
Query: 1081 SG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+G + +G S+ + + + V D S+++W + +S + + H I
Sbjct: 173 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVR---DSMCRQTFIGHESDI 229
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVS 1194
A + TGS D + +++ L + ++ H +I+ T VA S + + +++
Sbjct: 230 NAVAFFPNGYAFTTGSDDATCRLFDLRADQ-ELLMYSHDNIICGITSVAFSRSGRL-LLA 287
Query: 1195 GSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
G D N +WD +V+C+ VT DG + + D L IW
Sbjct: 288 GYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 51.6 bits (118), Expect = 2e-05
Identities = 43/218 (19%), Positives = 93/218 (42%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
+ DN I+SL + N +R H ++C D+Q ++T S D + +
Sbjct: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ G+ + GHS V ++++ +T VSG+ D ++ +WD+
Sbjct: 169 WDIETGQQTVGFAGHSGDVMSLSLAPDGRT-FVSGACDASIKLWDVRDSMCRQTFIGHES 227
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ V +G + ++D T +++ + L +S
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYS 265
Score = 51.6 bits (118), Expect = 2e-05
Identities = 41/152 (26%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP G+ V +LW + + TF GH I + TGS+D +
Sbjct: 190 LSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDAT 249
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + + H I + VA + L+++G DD I + G L
Sbjct: 250 CRLFDLRA-DQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVL 308
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 50.0 bits (114), Expect = 6e-05
Identities = 31/147 (21%), Positives = 60/147 (40%), Gaps = 5/147 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +KVH S ++ ++ G D ++ L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + ++ S GD + + + G H G V
Sbjct: 130 EGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCA-LWDIETGQQTVGFAGHSGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVEN 809
S+ + DG F++G+ D ++ W+V +
Sbjct: 189 SLSLAPDGRTFVSGACDASIKLWDVRD 215
Score = 48.0 bits (109), Expect = 2e-04
Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 5/124 (4%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I SL +G + +L H G ++ + + D I IT S D T
Sbjct: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQI-ITSSGDTTCAL 168
Query: 805 WNVE 808
W++E
Sbjct: 169 WDIE 172
Score = 46.8 bits (106), Expect = 6e-04
Identities = 34/154 (22%), Positives = 62/154 (40%), Gaps = 5/154 (3%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ L ++ DG+ SG +++W + + T GH I V F PN +GS+
Sbjct: 187 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSD 246
Query: 1029 DRTVVVWQLADNSPSLTYKGHS--SAIQTLLMMSDGRRAMSSDRARNVHVWLV---DSGI 1083
D T ++ L + L Y + I ++ GR ++ N ++W D
Sbjct: 247 DATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAG 306
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
VL + + VT + D+ ++IW+
Sbjct: 307 VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 44.8 bits (101), Expect = 0.002
Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 101 MTC-AYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDN--QI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
++ S D +WDI T V + + DG VS A D ++ +W+ + +
Sbjct: 158 ITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSM 217
Query: 1253 ALTSFSLH 1260
+F H
Sbjct: 218 CRQTFIGH 225
Score = 38.3 bits (85), Expect = 0.20
Identities = 55/306 (17%), Positives = 103/306 (33%), Gaps = 25/306 (8%)
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H+A + + + L++S D +II V + V + GN
Sbjct: 54 HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVA 113
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVT-----DDNVFLLTLQGDNELHLRTFI 849
G D ++++ V+ +P H ++ DDN ++T GD L
Sbjct: 114 CGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCALWDIE 172
Query: 850 TGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXX 909
TG H V +A D G D I L+ + + +T
Sbjct: 173 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAV 232
Query: 910 XXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPI 969
+ G + T F + R +++ L+ + + + I
Sbjct: 233 AFFPNGYAFTTGSDDATCRLF-------DLRADQEL------------LMYSHDNIICGI 273
Query: 970 SCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSED 1029
+ + SR G+L +G +W L GH ++C+ + + + V +GS D
Sbjct: 274 TSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
Query: 1030 RTVVVW 1035
+ +W
Sbjct: 334 SFLKIW 339
>CR541729-1|CAG46530.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 80.6 bits (190), Expect = 4e-14
Identities = 58/238 (24%), Positives = 106/238 (44%), Gaps = 16/238 (6%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N ++ S S D T
Sbjct: 109 GNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + ++ + GHS + +L + DGR +S ++ +W V + + G +
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES 227
Query: 1094 SIDVTLNMK--YAVLSDGDNSV-RIWSLAGGDNSEDNRRSVSHAE---RITCFALTADSQ 1147
I+ YA + D++ R++ L ++ SH IT A + +
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDL----RADQELLMYSHDNIICGITSVAFSRSGR 283
Query: 1148 HVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
++ G D + +W G + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 284 LLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 340
Score = 65.7 bits (153), Expect = 1e-09
Identities = 48/198 (24%), Positives = 81/198 (40%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + GH G + ++ +P+ +SG+
Sbjct: 146 LSCCRFLDDNQIITSS-GDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR--RAMSSDRARNVHVWLVDSGIVLH 1086
D ++ +W + D+ T+ GH S I + +G S D + D ++++
Sbjct: 205 DASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V + +L G D + IW GD + H R++C +T
Sbjct: 265 SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 322 DDGMAVATGSWDSFLKIW 339
Score = 60.1 bits (139), Expect = 6e-08
Identities = 52/261 (19%), Positives = 101/261 (38%), Gaps = 12/261 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSATGPSASIDVT----LNMKYAVLSDGDNS 1112
G D +++ G V S P + ++ L+ + S GD +
Sbjct: 106 APSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + G + H+ + +L D + V+G+ D S+K+W + Q
Sbjct: 166 CALWDIETGQQTVG---FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
+GH + VA N +GS D ++D+ +T V +
Sbjct: 223 IGHESDINAVAF-FPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRS 281
Query: 1231 GTIAVSCAEDKTLIIWETKRG 1251
G + ++ +D IW+ +G
Sbjct: 282 GRLLLAGYDDFNCNIWDAMKG 302
Score = 56.8 bits (131), Expect = 5e-07
Identities = 45/201 (22%), Positives = 81/201 (40%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T H V+ ++ +
Sbjct: 141 GHTGYLSC-CRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NF 810
+SG D+++ + + D H + +V +G F TGS D T +++ +
Sbjct: 200 VSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQ 259
Query: 811 TLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
LL + I V L L G ++ + + + G L H +V C
Sbjct: 260 ELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLKIWN 340
Score = 55.2 bits (127), Expect = 2e-06
Identities = 44/180 (24%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Query: 672 SAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK 729
S+GD LW I + + F GHSG ++ + + + + ++G+ D S+ +WD+ +
Sbjct: 160 SSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCR 219
Query: 730 TKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSVKVI 787
+ H + + VA N +G DD+ + L D L+ D+ +TSV
Sbjct: 220 QTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFS 279
Query: 788 QDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNELHL 845
+ G + + G D W+ + V AG + VTDD + + T D+ L +
Sbjct: 280 RSGRLLLAGYDDFNCNIWDAMKGD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 338
Score = 53.2 bits (122), Expect = 7e-06
Identities = 59/292 (20%), Positives = 117/292 (40%), Gaps = 18/292 (6%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNFVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDT-TCALWDIE 172
Query: 1081 SG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+G + +G S+ + + + V D S+++W + +S + + H I
Sbjct: 173 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVR---DSMCRQTFIGHESDI 229
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVS 1194
A + TGS D + +++ L + ++ H +I+ T VA S + + +++
Sbjct: 230 NAVAFFPNGYAFTTGSDDATCRLFDLRADQ-ELLMYSHDNIICGITSVAFSRSGRL-LLA 287
Query: 1195 GSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
G D N +WD +V+C+ VT DG + + D L IW
Sbjct: 288 GYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 51.6 bits (118), Expect = 2e-05
Identities = 43/218 (19%), Positives = 93/218 (42%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
+ DN I+SL + N +R H ++C D+Q ++T S D + +
Sbjct: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ G+ + GHS V ++++ +T VSG+ D ++ +WD+
Sbjct: 169 WDIETGQQTVGFAGHSGDVMSLSLAPDGRT-FVSGACDASIKLWDVRDSMCRQTFIGHES 227
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ V +G + ++D T +++ + L +S
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYS 265
Score = 51.6 bits (118), Expect = 2e-05
Identities = 41/152 (26%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP G+ V +LW + + TF GH I + TGS+D +
Sbjct: 190 LSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDAT 249
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + + H I + VA + L+++G DD I + G L
Sbjct: 250 CRLFDLRA-DQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVL 308
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 50.0 bits (114), Expect = 6e-05
Identities = 31/147 (21%), Positives = 60/147 (40%), Gaps = 5/147 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +KVH S ++ ++ G D ++ L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + ++ S GD + + + G H G V
Sbjct: 130 EGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCA-LWDIETGQQTVGFAGHSGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVEN 809
S+ + DG F++G+ D ++ W+V +
Sbjct: 189 SLSLAPDGRTFVSGACDASIKLWDVRD 215
Score = 48.0 bits (109), Expect = 2e-04
Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 5/124 (4%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I SL +G + +L H G ++ + + D I IT S D T
Sbjct: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQI-ITSSGDTTCAL 168
Query: 805 WNVE 808
W++E
Sbjct: 169 WDIE 172
Score = 46.8 bits (106), Expect = 6e-04
Identities = 34/154 (22%), Positives = 62/154 (40%), Gaps = 5/154 (3%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ L ++ DG+ SG +++W + + T GH I V F PN +GS+
Sbjct: 187 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSD 246
Query: 1029 DRTVVVWQLADNSPSLTYKGHS--SAIQTLLMMSDGRRAMSSDRARNVHVWLV---DSGI 1083
D T ++ L + L Y + I ++ GR ++ N ++W D
Sbjct: 247 DATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAG 306
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
VL + + VT + D+ ++IW+
Sbjct: 307 VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 44.8 bits (101), Expect = 0.002
Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 101 MTC-AYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDN--QI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
++ S D +WDI T V + + DG VS A D ++ +W+ + +
Sbjct: 158 ITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSM 217
Query: 1253 ALTSFSLH 1260
+F H
Sbjct: 218 CRQTFIGH 225
Score = 38.3 bits (85), Expect = 0.20
Identities = 55/306 (17%), Positives = 103/306 (33%), Gaps = 25/306 (8%)
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H+A + + + L++S D +II V + V + GN
Sbjct: 54 HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVA 113
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVT-----DDNVFLLTLQGDNELHLRTFI 849
G D ++++ V+ +P H ++ DDN ++T GD L
Sbjct: 114 CGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCALWDIE 172
Query: 850 TGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXX 909
TG H V +A D G D I L+ + + +T
Sbjct: 173 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAV 232
Query: 910 XXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPI 969
+ G + T F + R +++ L+ + + + I
Sbjct: 233 AFFPNGYAFTTGSDDATCRLF-------DLRADQEL------------LMYSHDNIICGI 273
Query: 970 SCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSED 1029
+ + SR G+L +G +W L GH ++C+ + + + V +GS D
Sbjct: 274 TSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
Query: 1030 RTVVVW 1035
+ +W
Sbjct: 334 SFLKIW 339
>BC068003-1|AAH68003.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 80.6 bits (190), Expect = 4e-14
Identities = 58/238 (24%), Positives = 106/238 (44%), Gaps = 16/238 (6%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N ++ S S D T
Sbjct: 109 GNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + ++ + GHS + +L + DGR +S ++ +W V + + G +
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES 227
Query: 1094 SIDVTLNMK--YAVLSDGDNSV-RIWSLAGGDNSEDNRRSVSHAE---RITCFALTADSQ 1147
I+ YA + D++ R++ L ++ SH IT A + +
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDL----RADQELLMYSHDNIICGITSVAFSRSGR 283
Query: 1148 HVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
++ G D + +W G + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 284 LLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 340
Score = 65.7 bits (153), Expect = 1e-09
Identities = 48/198 (24%), Positives = 81/198 (40%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + GH G + ++ +P+ +SG+
Sbjct: 146 LSCCRFLDDNQIITSS-GDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR--RAMSSDRARNVHVWLVDSGIVLH 1086
D ++ +W + D+ T+ GH S I + +G S D + D ++++
Sbjct: 205 DASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V + +L G D + IW GD + H R++C +T
Sbjct: 265 SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 322 DDGMAVATGSWDSFLKIW 339
Score = 60.1 bits (139), Expect = 6e-08
Identities = 52/261 (19%), Positives = 101/261 (38%), Gaps = 12/261 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSATGPSASIDVT----LNMKYAVLSDGDNS 1112
G D +++ G V S P + ++ L+ + S GD +
Sbjct: 106 APSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + G + H+ + +L D + V+G+ D S+K+W + Q
Sbjct: 166 CALWDIETGQQTVG---FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
+GH + VA N +GS D ++D+ +T V +
Sbjct: 223 IGHESDINAVAF-FPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRS 281
Query: 1231 GTIAVSCAEDKTLIIWETKRG 1251
G + ++ +D IW+ +G
Sbjct: 282 GRLLLAGYDDFNCNIWDAMKG 302
Score = 56.8 bits (131), Expect = 5e-07
Identities = 45/201 (22%), Positives = 81/201 (40%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T H V+ ++ +
Sbjct: 141 GHTGYLSC-CRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NF 810
+SG D+++ + + D H + +V +G F TGS D T +++ +
Sbjct: 200 VSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQ 259
Query: 811 TLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
LL + I V L L G ++ + + + G L H +V C
Sbjct: 260 ELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLKIWN 340
Score = 55.2 bits (127), Expect = 2e-06
Identities = 44/180 (24%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Query: 672 SAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK 729
S+GD LW I + + F GHSG ++ + + + + ++G+ D S+ +WD+ +
Sbjct: 160 SSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCR 219
Query: 730 TKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSVKVI 787
+ H + + VA N +G DD+ + L D L+ D+ +TSV
Sbjct: 220 QTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFS 279
Query: 788 QDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNELHL 845
+ G + + G D W+ + V AG + VTDD + + T D+ L +
Sbjct: 280 RSGRLLLAGYDDFNCNIWDAMKGD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 338
Score = 53.2 bits (122), Expect = 7e-06
Identities = 59/292 (20%), Positives = 117/292 (40%), Gaps = 18/292 (6%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNFVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDT-TCALWDIE 172
Query: 1081 SG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+G + +G S+ + + + V D S+++W + +S + + H I
Sbjct: 173 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVR---DSMCRQTFIGHESDI 229
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVS 1194
A + TGS D + +++ L + ++ H +I+ T VA S + + +++
Sbjct: 230 NAVAFFPNGYAFTTGSDDATCRLFDLRADQ-ELLMYSHDNIICGITSVAFSRSGRL-LLA 287
Query: 1195 GSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
G D N +WD +V+C+ VT DG + + D L IW
Sbjct: 288 GYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 51.6 bits (118), Expect = 2e-05
Identities = 43/218 (19%), Positives = 93/218 (42%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
+ DN I+SL + N +R H ++C D+Q ++T S D + +
Sbjct: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ G+ + GHS V ++++ +T VSG+ D ++ +WD+
Sbjct: 169 WDIETGQQTVGFAGHSGDVMSLSLAPDGRT-FVSGACDASIKLWDVRDSMCRQTFIGHES 227
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ V +G + ++D T +++ + L +S
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYS 265
Score = 51.6 bits (118), Expect = 2e-05
Identities = 41/152 (26%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP G+ V +LW + + TF GH I + TGS+D +
Sbjct: 190 LSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDAT 249
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + + H I + VA + L+++G DD I + G L
Sbjct: 250 CRLFDLRA-DQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVL 308
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 50.0 bits (114), Expect = 6e-05
Identities = 31/147 (21%), Positives = 60/147 (40%), Gaps = 5/147 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +KVH S ++ ++ G D ++ L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + ++ S GD + + + G H G V
Sbjct: 130 EGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCA-LWDIETGQQTVGFAGHSGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVEN 809
S+ + DG F++G+ D ++ W+V +
Sbjct: 189 SLSLAPDGRTFVSGACDASIKLWDVRD 215
Score = 48.0 bits (109), Expect = 2e-04
Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 5/124 (4%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I SL +G + +L H G ++ + + D I IT S D T
Sbjct: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQI-ITSSGDTTCAL 168
Query: 805 WNVE 808
W++E
Sbjct: 169 WDIE 172
Score = 46.8 bits (106), Expect = 6e-04
Identities = 34/154 (22%), Positives = 62/154 (40%), Gaps = 5/154 (3%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ L ++ DG+ SG +++W + + T GH I V F PN +GS+
Sbjct: 187 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSD 246
Query: 1029 DRTVVVWQLADNSPSLTYKGHS--SAIQTLLMMSDGRRAMSSDRARNVHVWLV---DSGI 1083
D T ++ L + L Y + I ++ GR ++ N ++W D
Sbjct: 247 DATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAG 306
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
VL + + VT + D+ ++IW+
Sbjct: 307 VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 44.8 bits (101), Expect = 0.002
Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 101 MTC-AYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDN--QI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
++ S D +WDI T V + + DG VS A D ++ +W+ + +
Sbjct: 158 ITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSM 217
Query: 1253 ALTSFSLH 1260
+F H
Sbjct: 218 CRQTFIGH 225
Score = 38.3 bits (85), Expect = 0.20
Identities = 55/306 (17%), Positives = 103/306 (33%), Gaps = 25/306 (8%)
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H+A + + + L++S D +II V + V + GN
Sbjct: 54 HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVA 113
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVT-----DDNVFLLTLQGDNELHLRTFI 849
G D ++++ V+ +P H ++ DDN ++T GD L
Sbjct: 114 CGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCALWDIE 172
Query: 850 TGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXX 909
TG H V +A D G D I L+ + + +T
Sbjct: 173 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAV 232
Query: 910 XXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPI 969
+ G + T F + R +++ L+ + + + I
Sbjct: 233 AFFPNGYAFTTGSDDATCRLF-------DLRADQEL------------LMYSHDNIICGI 273
Query: 970 SCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSED 1029
+ + SR G+L +G +W L GH ++C+ + + + V +GS D
Sbjct: 274 TSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
Query: 1030 RTVVVW 1035
+ +W
Sbjct: 334 SFLKIW 339
>BC012348-1|AAH12348.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 80.6 bits (190), Expect = 4e-14
Identities = 58/238 (24%), Positives = 106/238 (44%), Gaps = 16/238 (6%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N ++ S S D T
Sbjct: 109 GNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + ++ + GHS + +L + DGR +S ++ +W V + + G +
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES 227
Query: 1094 SIDVTLNMK--YAVLSDGDNSV-RIWSLAGGDNSEDNRRSVSHAE---RITCFALTADSQ 1147
I+ YA + D++ R++ L ++ SH IT A + +
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDL----RADQELLMYSHDNIICGITSVAFSRSGR 283
Query: 1148 HVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
++ G D + +W G + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 284 LLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 340
Score = 65.7 bits (153), Expect = 1e-09
Identities = 48/198 (24%), Positives = 81/198 (40%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + GH G + ++ +P+ +SG+
Sbjct: 146 LSCCRFLDDNQIITSS-GDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR--RAMSSDRARNVHVWLVDSGIVLH 1086
D ++ +W + D+ T+ GH S I + +G S D + D ++++
Sbjct: 205 DASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V + +L G D + IW GD + H R++C +T
Sbjct: 265 SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 322 DDGMAVATGSWDSFLKIW 339
Score = 60.1 bits (139), Expect = 6e-08
Identities = 52/261 (19%), Positives = 101/261 (38%), Gaps = 12/261 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSATGPSASIDVT----LNMKYAVLSDGDNS 1112
G D +++ G V S P + ++ L+ + S GD +
Sbjct: 106 APSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + G + H+ + +L D + V+G+ D S+K+W + Q
Sbjct: 166 CALWDIETGQQTVG---FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
+GH + VA N +GS D ++D+ +T V +
Sbjct: 223 IGHESDINAVAF-FPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRS 281
Query: 1231 GTIAVSCAEDKTLIIWETKRG 1251
G + ++ +D IW+ +G
Sbjct: 282 GRLLLAGYDDFNCNIWDAMKG 302
Score = 56.8 bits (131), Expect = 5e-07
Identities = 45/201 (22%), Positives = 81/201 (40%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T H V+ ++ +
Sbjct: 141 GHTGYLSC-CRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NF 810
+SG D+++ + + D H + +V +G F TGS D T +++ +
Sbjct: 200 VSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQ 259
Query: 811 TLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
LL + I V L L G ++ + + + G L H +V C
Sbjct: 260 ELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLKIWN 340
Score = 55.2 bits (127), Expect = 2e-06
Identities = 44/180 (24%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Query: 672 SAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK 729
S+GD LW I + + F GHSG ++ + + + + ++G+ D S+ +WD+ +
Sbjct: 160 SSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCR 219
Query: 730 TKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSVKVI 787
+ H + + VA N +G DD+ + L D L+ D+ +TSV
Sbjct: 220 QTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFS 279
Query: 788 QDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNELHL 845
+ G + + G D W+ + V AG + VTDD + + T D+ L +
Sbjct: 280 RSGRLLLAGYDDFNCNIWDAMKGD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 338
Score = 53.2 bits (122), Expect = 7e-06
Identities = 59/292 (20%), Positives = 117/292 (40%), Gaps = 18/292 (6%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNFVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDT-TCALWDIE 172
Query: 1081 SG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+G + +G S+ + + + V D S+++W + +S + + H I
Sbjct: 173 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVR---DSMCRQTFIGHESDI 229
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVS 1194
A + TGS D + +++ L + ++ H +I+ T VA S + + +++
Sbjct: 230 NAVAFFPNGYAFTTGSDDATCRLFDLRADQ-ELLMYSHDNIICGITSVAFSRSGRL-LLA 287
Query: 1195 GSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
G D N +WD +V+C+ VT DG + + D L IW
Sbjct: 288 GYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 51.6 bits (118), Expect = 2e-05
Identities = 43/218 (19%), Positives = 93/218 (42%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
+ DN I+SL + N +R H ++C D+Q ++T S D + +
Sbjct: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ G+ + GHS V ++++ +T VSG+ D ++ +WD+
Sbjct: 169 WDIETGQQTVGFAGHSGDVMSLSLAPDGRT-FVSGACDASIKLWDVRDSMCRQTFIGHES 227
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ V +G + ++D T +++ + L +S
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYS 265
Score = 51.6 bits (118), Expect = 2e-05
Identities = 41/152 (26%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP G+ V +LW + + TF GH I + TGS+D +
Sbjct: 190 LSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDAT 249
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + + H I + VA + L+++G DD I + G L
Sbjct: 250 CRLFDLRA-DQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVL 308
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 50.0 bits (114), Expect = 6e-05
Identities = 31/147 (21%), Positives = 60/147 (40%), Gaps = 5/147 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +KVH S ++ ++ G D ++ L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + ++ S GD + + + G H G V
Sbjct: 130 EGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCA-LWDIETGQQTVGFAGHSGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVEN 809
S+ + DG F++G+ D ++ W+V +
Sbjct: 189 SLSLAPDGRTFVSGACDASIKLWDVRD 215
Score = 48.0 bits (109), Expect = 2e-04
Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 5/124 (4%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I SL +G + +L H G ++ + + D I IT S D T
Sbjct: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQI-ITSSGDTTCAL 168
Query: 805 WNVE 808
W++E
Sbjct: 169 WDIE 172
Score = 46.8 bits (106), Expect = 6e-04
Identities = 34/154 (22%), Positives = 62/154 (40%), Gaps = 5/154 (3%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ L ++ DG+ SG +++W + + T GH I V F PN +GS+
Sbjct: 187 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSD 246
Query: 1029 DRTVVVWQLADNSPSLTYKGHS--SAIQTLLMMSDGRRAMSSDRARNVHVWLV---DSGI 1083
D T ++ L + L Y + I ++ GR ++ N ++W D
Sbjct: 247 DATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAG 306
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
VL + + VT + D+ ++IW+
Sbjct: 307 VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 44.8 bits (101), Expect = 0.002
Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 101 MTC-AYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDN--QI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
++ S D +WDI T V + + DG VS A D ++ +W+ + +
Sbjct: 158 ITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSM 217
Query: 1253 ALTSFSLH 1260
+F H
Sbjct: 218 CRQTFIGH 225
Score = 38.3 bits (85), Expect = 0.20
Identities = 55/306 (17%), Positives = 103/306 (33%), Gaps = 25/306 (8%)
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H+A + + + L++S D +II V + V + GN
Sbjct: 54 HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVA 113
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVT-----DDNVFLLTLQGDNELHLRTFI 849
G D ++++ V+ +P H ++ DDN ++T GD L
Sbjct: 114 CGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCALWDIE 172
Query: 850 TGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXX 909
TG H V +A D G D I L+ + + +T
Sbjct: 173 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAV 232
Query: 910 XXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPI 969
+ G + T F + R +++ L+ + + + I
Sbjct: 233 AFFPNGYAFTTGSDDATCRLF-------DLRADQEL------------LMYSHDNIICGI 273
Query: 970 SCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSED 1029
+ + SR G+L +G +W L GH ++C+ + + + V +GS D
Sbjct: 274 TSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
Query: 1030 RTVVVW 1035
+ +W
Sbjct: 334 SFLKIW 339
>BC010073-1|AAH10073.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 80.6 bits (190), Expect = 4e-14
Identities = 58/238 (24%), Positives = 106/238 (44%), Gaps = 16/238 (6%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N ++ S S D T
Sbjct: 109 GNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + ++ + GHS + +L + DGR +S ++ +W V + + G +
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES 227
Query: 1094 SIDVTLNMK--YAVLSDGDNSV-RIWSLAGGDNSEDNRRSVSHAE---RITCFALTADSQ 1147
I+ YA + D++ R++ L ++ SH IT A + +
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDL----RADQELLMYSHDNIICGITSVAFSRSGR 283
Query: 1148 HVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
++ G D + +W G + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 284 LLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 340
Score = 65.7 bits (153), Expect = 1e-09
Identities = 48/198 (24%), Positives = 81/198 (40%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + GH G + ++ +P+ +SG+
Sbjct: 146 LSCCRFLDDNQIITSS-GDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR--RAMSSDRARNVHVWLVDSGIVLH 1086
D ++ +W + D+ T+ GH S I + +G S D + D ++++
Sbjct: 205 DASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V + +L G D + IW GD + H R++C +T
Sbjct: 265 SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 322 DDGMAVATGSWDSFLKIW 339
Score = 60.1 bits (139), Expect = 6e-08
Identities = 52/261 (19%), Positives = 101/261 (38%), Gaps = 12/261 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSATGPSASIDVT----LNMKYAVLSDGDNS 1112
G D +++ G V S P + ++ L+ + S GD +
Sbjct: 106 APSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + G + H+ + +L D + V+G+ D S+K+W + Q
Sbjct: 166 CALWDIETGQQTVG---FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
+GH + VA N +GS D ++D+ +T V +
Sbjct: 223 IGHESDINAVAF-FPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRS 281
Query: 1231 GTIAVSCAEDKTLIIWETKRG 1251
G + ++ +D IW+ +G
Sbjct: 282 GRLLLAGYDDFNCNIWDAMKG 302
Score = 56.8 bits (131), Expect = 5e-07
Identities = 45/201 (22%), Positives = 81/201 (40%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T H V+ ++ +
Sbjct: 141 GHTGYLSC-CRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NF 810
+SG D+++ + + D H + +V +G F TGS D T +++ +
Sbjct: 200 VSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQ 259
Query: 811 TLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
LL + I V L L G ++ + + + G L H +V C
Sbjct: 260 ELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLKIWN 340
Score = 55.2 bits (127), Expect = 2e-06
Identities = 44/180 (24%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Query: 672 SAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK 729
S+GD LW I + + F GHSG ++ + + + + ++G+ D S+ +WD+ +
Sbjct: 160 SSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCR 219
Query: 730 TKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSVKVI 787
+ H + + VA N +G DD+ + L D L+ D+ +TSV
Sbjct: 220 QTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFS 279
Query: 788 QDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNELHL 845
+ G + + G D W+ + V AG + VTDD + + T D+ L +
Sbjct: 280 RSGRLLLAGYDDFNCNIWDAMKGD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 338
Score = 53.2 bits (122), Expect = 7e-06
Identities = 59/292 (20%), Positives = 117/292 (40%), Gaps = 18/292 (6%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNFVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDT-TCALWDIE 172
Query: 1081 SG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+G + +G S+ + + + V D S+++W + +S + + H I
Sbjct: 173 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVR---DSMCRQTFIGHESDI 229
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVS 1194
A + TGS D + +++ L + ++ H +I+ T VA S + + +++
Sbjct: 230 NAVAFFPNGYAFTTGSDDATCRLFDLRADQ-ELLMYSHDNIICGITSVAFSRSGRL-LLA 287
Query: 1195 GSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
G D N +WD +V+C+ VT DG + + D L IW
Sbjct: 288 GYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 51.6 bits (118), Expect = 2e-05
Identities = 43/218 (19%), Positives = 93/218 (42%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
+ DN I+SL + N +R H ++C D+Q ++T S D + +
Sbjct: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ G+ + GHS V ++++ +T VSG+ D ++ +WD+
Sbjct: 169 WDIETGQQTVGFAGHSGDVMSLSLAPDGRT-FVSGACDASIKLWDVRDSMCRQTFIGHES 227
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ V +G + ++D T +++ + L +S
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYS 265
Score = 51.6 bits (118), Expect = 2e-05
Identities = 41/152 (26%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP G+ V +LW + + TF GH I + TGS+D +
Sbjct: 190 LSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDAT 249
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + + H I + VA + L+++G DD I + G L
Sbjct: 250 CRLFDLRA-DQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVL 308
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 50.0 bits (114), Expect = 6e-05
Identities = 31/147 (21%), Positives = 60/147 (40%), Gaps = 5/147 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +KVH S ++ ++ G D ++ L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + ++ S GD + + + G H G V
Sbjct: 130 EGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCA-LWDIETGQQTVGFAGHSGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVEN 809
S+ + DG F++G+ D ++ W+V +
Sbjct: 189 SLSLAPDGRTFVSGACDASIKLWDVRD 215
Score = 48.0 bits (109), Expect = 2e-04
Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 5/124 (4%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I SL +G + +L H G ++ + + D I IT S D T
Sbjct: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQI-ITSSGDTTCAL 168
Query: 805 WNVE 808
W++E
Sbjct: 169 WDIE 172
Score = 46.8 bits (106), Expect = 6e-04
Identities = 34/154 (22%), Positives = 62/154 (40%), Gaps = 5/154 (3%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ L ++ DG+ SG +++W + + T GH I V F PN +GS+
Sbjct: 187 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSD 246
Query: 1029 DRTVVVWQLADNSPSLTYKGHS--SAIQTLLMMSDGRRAMSSDRARNVHVWLV---DSGI 1083
D T ++ L + L Y + I ++ GR ++ N ++W D
Sbjct: 247 DATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAG 306
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
VL + + VT + D+ ++IW+
Sbjct: 307 VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 44.8 bits (101), Expect = 0.002
Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 101 MTC-AYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDN--QI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
++ S D +WDI T V + + DG VS A D ++ +W+ + +
Sbjct: 158 ITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSM 217
Query: 1253 ALTSFSLH 1260
+F H
Sbjct: 218 CRQTFIGH 225
Score = 38.3 bits (85), Expect = 0.20
Identities = 55/306 (17%), Positives = 103/306 (33%), Gaps = 25/306 (8%)
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H+A + + + L++S D +II V + V + GN
Sbjct: 54 HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVA 113
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVT-----DDNVFLLTLQGDNELHLRTFI 849
G D ++++ V+ +P H ++ DDN ++T GD L
Sbjct: 114 CGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCALWDIE 172
Query: 850 TGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXX 909
TG H V +A D G D I L+ + + +T
Sbjct: 173 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAV 232
Query: 910 XXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPI 969
+ G + T F + R +++ L+ + + + I
Sbjct: 233 AFFPNGYAFTTGSDDATCRLF-------DLRADQEL------------LMYSHDNIICGI 273
Query: 970 SCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSED 1029
+ + SR G+L +G +W L GH ++C+ + + + V +GS D
Sbjct: 274 TSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
Query: 1030 RTVVVW 1035
+ +W
Sbjct: 334 SFLKIW 339
>AF501883-1|AAM15919.1| 340|Homo sapiens guanine nucleotide binding
protein beta 2 protein.
Length = 340
Score = 80.6 bits (190), Expect = 4e-14
Identities = 58/238 (24%), Positives = 106/238 (44%), Gaps = 16/238 (6%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N ++ S S D T
Sbjct: 109 GNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + ++ + GHS + +L + DGR +S ++ +W V + + G +
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES 227
Query: 1094 SIDVTLNMK--YAVLSDGDNSV-RIWSLAGGDNSEDNRRSVSHAE---RITCFALTADSQ 1147
I+ YA + D++ R++ L ++ SH IT A + +
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDL----RADQELLMYSHDNIICGITSVAFSRSGR 283
Query: 1148 HVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
++ G D + +W G + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 284 LLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 340
Score = 65.7 bits (153), Expect = 1e-09
Identities = 48/198 (24%), Positives = 81/198 (40%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + GH G + ++ +P+ +SG+
Sbjct: 146 LSCCRFLDDNQIITSS-GDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR--RAMSSDRARNVHVWLVDSGIVLH 1086
D ++ +W + D+ T+ GH S I + +G S D + D ++++
Sbjct: 205 DASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V + +L G D + IW GD + H R++C +T
Sbjct: 265 SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 322 DDGMAVATGSWDSFLKIW 339
Score = 60.1 bits (139), Expect = 6e-08
Identities = 52/261 (19%), Positives = 101/261 (38%), Gaps = 12/261 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSATGPSASIDVT----LNMKYAVLSDGDNS 1112
G D +++ G V S P + ++ L+ + S GD +
Sbjct: 106 APSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + G + H+ + +L D + V+G+ D S+K+W + Q
Sbjct: 166 CALWDIETGQQTVG---FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
+GH + VA N +GS D ++D+ +T V +
Sbjct: 223 IGHESDINAVAF-FPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRS 281
Query: 1231 GTIAVSCAEDKTLIIWETKRG 1251
G + ++ +D IW+ +G
Sbjct: 282 GRLLLAGYDDFNCNIWDAMKG 302
Score = 56.8 bits (131), Expect = 5e-07
Identities = 45/201 (22%), Positives = 81/201 (40%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T H V+ ++ +
Sbjct: 141 GHTGYLSC-CRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NF 810
+SG D+++ + + D H + +V +G F TGS D T +++ +
Sbjct: 200 VSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQ 259
Query: 811 TLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
LL + I V L L G ++ + + + G L H +V C
Sbjct: 260 ELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLKIWN 340
Score = 55.2 bits (127), Expect = 2e-06
Identities = 44/180 (24%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Query: 672 SAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK 729
S+GD LW I + + F GHSG ++ + + + + ++G+ D S+ +WD+ +
Sbjct: 160 SSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCR 219
Query: 730 TKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSVKVI 787
+ H + + VA N +G DD+ + L D L+ D+ +TSV
Sbjct: 220 QTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFS 279
Query: 788 QDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNELHL 845
+ G + + G D W+ + V AG + VTDD + + T D+ L +
Sbjct: 280 RSGRLLLAGYDDFNCNIWDAMKGD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 338
Score = 53.2 bits (122), Expect = 7e-06
Identities = 59/292 (20%), Positives = 117/292 (40%), Gaps = 18/292 (6%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNFVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDT-TCALWDIE 172
Query: 1081 SG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+G + +G S+ + + + V D S+++W + +S + + H I
Sbjct: 173 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVR---DSMCRQTFIGHESDI 229
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVS 1194
A + TGS D + +++ L + ++ H +I+ T VA S + + +++
Sbjct: 230 NAVAFFPNGYAFTTGSDDATCRLFDLRADQ-ELLMYSHDNIICGITSVAFSRSGRL-LLA 287
Query: 1195 GSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
G D N +WD +V+C+ VT DG + + D L IW
Sbjct: 288 GYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 51.6 bits (118), Expect = 2e-05
Identities = 43/218 (19%), Positives = 93/218 (42%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
+ DN I+SL + N +R H ++C D+Q ++T S D + +
Sbjct: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ G+ + GHS V ++++ +T VSG+ D ++ +WD+
Sbjct: 169 WDIETGQQTVGFAGHSGDVMSLSLAPDGRT-FVSGACDASIKLWDVRDSMCRQTFIGHES 227
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ V +G + ++D T +++ + L +S
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYS 265
Score = 51.6 bits (118), Expect = 2e-05
Identities = 41/152 (26%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP G+ V +LW + + TF GH I + TGS+D +
Sbjct: 190 LSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDAT 249
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + + H I + VA + L+++G DD I + G L
Sbjct: 250 CRLFDLRA-DQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVL 308
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 50.0 bits (114), Expect = 6e-05
Identities = 31/147 (21%), Positives = 60/147 (40%), Gaps = 5/147 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +KVH S ++ ++ G D ++ L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + ++ S GD + + + G H G V
Sbjct: 130 EGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCA-LWDIETGQQTVGFAGHSGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVEN 809
S+ + DG F++G+ D ++ W+V +
Sbjct: 189 SLSLAPDGRTFVSGACDASIKLWDVRD 215
Score = 48.0 bits (109), Expect = 2e-04
Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 5/124 (4%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I SL +G + +L H G ++ + + D I IT S D T
Sbjct: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQI-ITSSGDTTCAL 168
Query: 805 WNVE 808
W++E
Sbjct: 169 WDIE 172
Score = 46.8 bits (106), Expect = 6e-04
Identities = 34/154 (22%), Positives = 62/154 (40%), Gaps = 5/154 (3%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ L ++ DG+ SG +++W + + T GH I V F PN +GS+
Sbjct: 187 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSD 246
Query: 1029 DRTVVVWQLADNSPSLTYKGHS--SAIQTLLMMSDGRRAMSSDRARNVHVWLV---DSGI 1083
D T ++ L + L Y + I ++ GR ++ N ++W D
Sbjct: 247 DATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAG 306
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
VL + + VT + D+ ++IW+
Sbjct: 307 VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 44.8 bits (101), Expect = 0.002
Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 101 MTC-AYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDN--QI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
++ S D +WDI T V + + DG VS A D ++ +W+ + +
Sbjct: 158 ITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSM 217
Query: 1253 ALTSFSLH 1260
+F H
Sbjct: 218 CRQTFIGH 225
Score = 38.3 bits (85), Expect = 0.20
Identities = 55/306 (17%), Positives = 103/306 (33%), Gaps = 25/306 (8%)
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H+A + + + L++S D +II V + V + GN
Sbjct: 54 HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVA 113
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVT-----DDNVFLLTLQGDNELHLRTFI 849
G D ++++ V+ +P H ++ DDN ++T GD L
Sbjct: 114 CGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCALWDIE 172
Query: 850 TGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXX 909
TG H V +A D G D I L+ + + +T
Sbjct: 173 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAV 232
Query: 910 XXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPI 969
+ G + T F + R +++ L+ + + + I
Sbjct: 233 AFFPNGYAFTTGSDDATCRLF-------DLRADQEL------------LMYSHDNIICGI 273
Query: 970 SCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSED 1029
+ + SR G+L +G +W L GH ++C+ + + + V +GS D
Sbjct: 274 TSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
Query: 1030 RTVVVW 1035
+ +W
Sbjct: 334 SFLKIW 339
>AF053356-4|AAC78794.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 80.6 bits (190), Expect = 4e-14
Identities = 58/238 (24%), Positives = 106/238 (44%), Gaps = 16/238 (6%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N ++ S S D T
Sbjct: 109 GNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + ++ + GHS + +L + DGR +S ++ +W V + + G +
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES 227
Query: 1094 SIDVTLNMK--YAVLSDGDNSV-RIWSLAGGDNSEDNRRSVSHAE---RITCFALTADSQ 1147
I+ YA + D++ R++ L ++ SH IT A + +
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDL----RADQELLMYSHDNIICGITSVAFSRSGR 283
Query: 1148 HVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
++ G D + +W G + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 284 LLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 340
Score = 65.7 bits (153), Expect = 1e-09
Identities = 48/198 (24%), Positives = 81/198 (40%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + GH G + ++ +P+ +SG+
Sbjct: 146 LSCCRFLDDNQIITSS-GDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR--RAMSSDRARNVHVWLVDSGIVLH 1086
D ++ +W + D+ T+ GH S I + +G S D + D ++++
Sbjct: 205 DASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V + +L G D + IW GD + H R++C +T
Sbjct: 265 SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 322 DDGMAVATGSWDSFLKIW 339
Score = 60.1 bits (139), Expect = 6e-08
Identities = 52/261 (19%), Positives = 101/261 (38%), Gaps = 12/261 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSATGPSASIDVT----LNMKYAVLSDGDNS 1112
G D +++ G V S P + ++ L+ + S GD +
Sbjct: 106 APSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + G + H+ + +L D + V+G+ D S+K+W + Q
Sbjct: 166 CALWDIETGQQTVG---FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
+GH + VA N +GS D ++D+ +T V +
Sbjct: 223 IGHESDINAVAF-FPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRS 281
Query: 1231 GTIAVSCAEDKTLIIWETKRG 1251
G + ++ +D IW+ +G
Sbjct: 282 GRLLLAGYDDFNCNIWDAMKG 302
Score = 56.8 bits (131), Expect = 5e-07
Identities = 45/201 (22%), Positives = 81/201 (40%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T H V+ ++ +
Sbjct: 141 GHTGYLSC-CRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NF 810
+SG D+++ + + D H + +V +G F TGS D T +++ +
Sbjct: 200 VSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQ 259
Query: 811 TLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
LL + I V L L G ++ + + + G L H +V C
Sbjct: 260 ELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLKIWN 340
Score = 55.2 bits (127), Expect = 2e-06
Identities = 44/180 (24%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Query: 672 SAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK 729
S+GD LW I + + F GHSG ++ + + + + ++G+ D S+ +WD+ +
Sbjct: 160 SSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCR 219
Query: 730 TKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSVKVI 787
+ H + + VA N +G DD+ + L D L+ D+ +TSV
Sbjct: 220 QTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFS 279
Query: 788 QDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNELHL 845
+ G + + G D W+ + V AG + VTDD + + T D+ L +
Sbjct: 280 RSGRLLLAGYDDFNCNIWDAMKGD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 338
Score = 53.2 bits (122), Expect = 7e-06
Identities = 59/292 (20%), Positives = 117/292 (40%), Gaps = 18/292 (6%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNFVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDT-TCALWDIE 172
Query: 1081 SG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+G + +G S+ + + + V D S+++W + +S + + H I
Sbjct: 173 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVR---DSMCRQTFIGHESDI 229
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVS 1194
A + TGS D + +++ L + ++ H +I+ T VA S + + +++
Sbjct: 230 NAVAFFPNGYAFTTGSDDATCRLFDLRADQ-ELLMYSHDNIICGITSVAFSRSGRL-LLA 287
Query: 1195 GSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
G D N +WD +V+C+ VT DG + + D L IW
Sbjct: 288 GYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 51.6 bits (118), Expect = 2e-05
Identities = 43/218 (19%), Positives = 93/218 (42%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
+ DN I+SL + N +R H ++C D+Q ++T S D + +
Sbjct: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ G+ + GHS V ++++ +T VSG+ D ++ +WD+
Sbjct: 169 WDIETGQQTVGFAGHSGDVMSLSLAPDGRT-FVSGACDASIKLWDVRDSMCRQTFIGHES 227
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ V +G + ++D T +++ + L +S
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYS 265
Score = 51.6 bits (118), Expect = 2e-05
Identities = 41/152 (26%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP G+ V +LW + + TF GH I + TGS+D +
Sbjct: 190 LSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDAT 249
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + + H I + VA + L+++G DD I + G L
Sbjct: 250 CRLFDLRA-DQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVL 308
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 50.0 bits (114), Expect = 6e-05
Identities = 31/147 (21%), Positives = 60/147 (40%), Gaps = 5/147 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +KVH S ++ ++ G D ++ L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + ++ S GD + + + G H G V
Sbjct: 130 EGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCA-LWDIETGQQTVGFAGHSGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVEN 809
S+ + DG F++G+ D ++ W+V +
Sbjct: 189 SLSLAPDGRTFVSGACDASIKLWDVRD 215
Score = 48.0 bits (109), Expect = 2e-04
Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 5/124 (4%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I SL +G + +L H G ++ + + D I IT S D T
Sbjct: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQI-ITSSGDTTCAL 168
Query: 805 WNVE 808
W++E
Sbjct: 169 WDIE 172
Score = 46.8 bits (106), Expect = 6e-04
Identities = 34/154 (22%), Positives = 62/154 (40%), Gaps = 5/154 (3%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ L ++ DG+ SG +++W + + T GH I V F PN +GS+
Sbjct: 187 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSD 246
Query: 1029 DRTVVVWQLADNSPSLTYKGHS--SAIQTLLMMSDGRRAMSSDRARNVHVWLV---DSGI 1083
D T ++ L + L Y + I ++ GR ++ N ++W D
Sbjct: 247 DATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAG 306
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
VL + + VT + D+ ++IW+
Sbjct: 307 VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 44.8 bits (101), Expect = 0.002
Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 101 MTC-AYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDN--QI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
++ S D +WDI T V + + DG VS A D ++ +W+ + +
Sbjct: 158 ITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSM 217
Query: 1253 ALTSFSLH 1260
+F H
Sbjct: 218 CRQTFIGH 225
Score = 38.3 bits (85), Expect = 0.20
Identities = 55/306 (17%), Positives = 103/306 (33%), Gaps = 25/306 (8%)
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H+A + + + L++S D +II V + V + GN
Sbjct: 54 HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVA 113
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVT-----DDNVFLLTLQGDNELHLRTFI 849
G D ++++ V+ +P H ++ DDN ++T GD L
Sbjct: 114 CGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCALWDIE 172
Query: 850 TGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXX 909
TG H V +A D G D I L+ + + +T
Sbjct: 173 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAV 232
Query: 910 XXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPI 969
+ G + T F + R +++ L+ + + + I
Sbjct: 233 AFFPNGYAFTTGSDDATCRLF-------DLRADQEL------------LMYSHDNIICGI 273
Query: 970 SCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSED 1029
+ + SR G+L +G +W L GH ++C+ + + + V +GS D
Sbjct: 274 TSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
Query: 1030 RTVVVW 1035
+ +W
Sbjct: 334 SFLKIW 339
>U72342-1|AAC51111.1| 410|Homo sapiens platelet activating factor
acetylhydrolase, brain isoform, 45 kDa subunit protein.
Length = 410
Score = 79.4 bits (187), Expect = 9e-14
Identities = 63/279 (22%), Positives = 114/279 (40%), Gaps = 25/279 (8%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR 1063
L+GH +T V F P +++S SED T+ VW T KGH+ ++Q + G+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 163
Query: 1064 RAMSSDRARNVHVWLVDSGIVLHSATGPS---ASIDVTLNMKYAVLSDGDNSVRIWSLAG 1120
S + +W + + G +S+ + N + V + D ++++W +
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
Query: 1121 GDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVT 1180
G + H E + D + + S D +++VW + + L H +V
Sbjct: 224 G---YCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 280
Query: 1181 CVA-------VSITNKTQ------------VVSGSWDCNLIVWDINTXXXXXXXXXXXXK 1221
C++ SI+ T ++SGS D + +WD++T
Sbjct: 281 CISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW 340
Query: 1222 VTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
V V G +SCA+DKTL +W+ K + + + H
Sbjct: 341 VRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAH 379
Score = 79.4 bits (187), Expect = 9e-14
Identities = 63/283 (22%), Positives = 117/283 (41%), Gaps = 27/283 (9%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
++VW T + TL GH + ++F + L+ S S D T+ +W T GH
Sbjct: 132 IKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGH 191
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLS- 1107
+ ++ +M +G +S+ R + + +W V +G + + TG + V N +++
Sbjct: 192 DHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 251
Query: 1108 -DGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQH------------------ 1148
D +VR+W +A + + R H + C + +S +
Sbjct: 252 CSNDQTVRVWVVATKECKAELR---EHEHVVECISWAPESSYSSISEATGSETKKSGKPG 308
Query: 1149 --VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+++GS D ++K+W + G LVGH + V V K ++S + D L VWD
Sbjct: 309 PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKF-ILSCADDKTLRVWDY 367
Query: 1207 NTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
VT + V+ + D+T+ +WE +
Sbjct: 368 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
Score = 54.8 bits (126), Expect = 2e-06
Identities = 40/201 (19%), Positives = 82/201 (40%), Gaps = 2/201 (0%)
Query: 675 DPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE 734
DP+ W I + + GH + + +++ SED ++ VWD T + +
Sbjct: 90 DPKEW-IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKG 148
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H V ++ + L+ S D + + + + H +V+SV ++ +G+ +
Sbjct: 149 HTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIV 208
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVP-IHIFDVTDDNVFLLTLQGDNELHLRTFITGTY 853
+ S+D T+ W V+ + T T + + D + + D + + T
Sbjct: 209 SASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKEC 268
Query: 854 LHPLKRHKAKVKCFCVAHDSS 874
L+ H+ V+C A +SS
Sbjct: 269 KAELREHEHVVECISWAPESS 289
Score = 52.4 bits (120), Expect = 1e-05
Identities = 35/141 (24%), Positives = 57/141 (40%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+V A ++W + T KGH+ S+ + + L + S D ++ +WD
Sbjct: 123 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 182
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
+ H V VA + N ++S D + + + G V HR V V+
Sbjct: 183 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRP 242
Query: 787 IQDGNIFITGSQDGTVCTWNV 807
QDG + + S D TV W V
Sbjct: 243 NQDGTLIASCSNDQTVRVWVV 263
Score = 52.0 bits (119), Expect = 2e-05
Identities = 58/310 (18%), Positives = 113/310 (36%), Gaps = 12/310 (3%)
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNV- 832
L HR VT V ++ ++ S+D T+ W+ E T+ G + D++ D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK-GHTDSVQDISFDHSG 162
Query: 833 -FLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLH 891
L + D + L F + + H V + + + D+ I ++ +
Sbjct: 163 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 892 SAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTK 951
+ ++T L+A+ N T+ + + + K R
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW-----VVATKECKAELREHEH 277
Query: 952 STTNITLL-QAEQSDLIPISCLEVSRDGQLGA---SGCARGLVRVWQLSTHRLQATLNGH 1007
I+ ++ S + + E + G+ G SG +++W +ST TL GH
Sbjct: 278 VVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGH 337
Query: 1008 IGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMS 1067
+ V F +LS ++D+T+ VW + T H + +L ++
Sbjct: 338 DNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVT 397
Query: 1068 SDRARNVHVW 1077
+ V VW
Sbjct: 398 GSVDQTVKVW 407
Score = 46.8 bits (106), Expect = 6e-04
Identities = 38/179 (21%), Positives = 71/179 (39%), Gaps = 20/179 (11%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
+ P+G H+V A ++W + + V TF GH + + ++ + + S D +V
Sbjct: 200 IMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVR 259
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRS--------------------LVISGGDDSA 759
VW + T K ++ EH V C++ S ++SG D
Sbjct: 260 VWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKT 319
Query: 760 VIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA 818
+ + + G + L H V V G ++ + D T+ W+ +N + T+ A
Sbjct: 320 IKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA 378
Score = 41.5 bits (93), Expect = 0.021
Identities = 26/98 (26%), Positives = 44/98 (44%)
Query: 708 YLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVD 767
+LL+GS D ++ +WD+ T ++ H V V ++S DD + + +
Sbjct: 310 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 369
Query: 768 GALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
+ L+ H VTS+ + +TGS D TV W
Sbjct: 370 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
Score = 34.3 bits (75), Expect = 3.3
Identities = 36/181 (19%), Positives = 73/181 (40%), Gaps = 4/181 (2%)
Query: 663 SGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWD 722
SG+ L + +LW + T GH ++ + + ++++ S D ++ +W+
Sbjct: 161 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 220
Query: 723 LHT-LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSV 781
+ T VKT H V V + +L+ S +D V + + +L H V
Sbjct: 221 VQTGYCVKT-FTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVV 279
Query: 782 TSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG-D 840
+ + + G+ + + L + + I ++DV+ + L+TL G D
Sbjct: 280 ECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVS-TGMCLMTLVGHD 338
Query: 841 N 841
N
Sbjct: 339 N 339
>L13386-1|AAA02881.1| 410|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 410
Score = 79.4 bits (187), Expect = 9e-14
Identities = 63/279 (22%), Positives = 114/279 (40%), Gaps = 25/279 (8%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR 1063
L+GH +T V F P +++S SED T+ VW T KGH+ ++Q + G+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 163
Query: 1064 RAMSSDRARNVHVWLVDSGIVLHSATGPS---ASIDVTLNMKYAVLSDGDNSVRIWSLAG 1120
S + +W + + G +S+ + N + V + D ++++W +
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
Query: 1121 GDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVT 1180
G + H E + D + + S D +++VW + + L H +V
Sbjct: 224 G---YCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 280
Query: 1181 CVA-------VSITNKTQ------------VVSGSWDCNLIVWDINTXXXXXXXXXXXXK 1221
C++ SI+ T ++SGS D + +WD++T
Sbjct: 281 CISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW 340
Query: 1222 VTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
V V G +SCA+DKTL +W+ K + + + H
Sbjct: 341 VRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAH 379
Score = 79.4 bits (187), Expect = 9e-14
Identities = 63/283 (22%), Positives = 117/283 (41%), Gaps = 27/283 (9%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
++VW T + TL GH + ++F + L+ S S D T+ +W T GH
Sbjct: 132 IKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGH 191
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLS- 1107
+ ++ +M +G +S+ R + + +W V +G + + TG + V N +++
Sbjct: 192 DHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 251
Query: 1108 -DGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQH------------------ 1148
D +VR+W +A + + R H + C + +S +
Sbjct: 252 CSNDQTVRVWVVATKECKAELR---EHEHVVECISWAPESSYSSISEATGSETKKSGKPG 308
Query: 1149 --VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+++GS D ++K+W + G LVGH + V V K ++S + D L VWD
Sbjct: 309 PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKF-ILSCADDKTLRVWDY 367
Query: 1207 NTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
VT + V+ + D+T+ +WE +
Sbjct: 368 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
Score = 54.8 bits (126), Expect = 2e-06
Identities = 40/201 (19%), Positives = 82/201 (40%), Gaps = 2/201 (0%)
Query: 675 DPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE 734
DP+ W I + + GH + + +++ SED ++ VWD T + +
Sbjct: 90 DPKEW-IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKG 148
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H V ++ + L+ S D + + + + H +V+SV ++ +G+ +
Sbjct: 149 HTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIV 208
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVP-IHIFDVTDDNVFLLTLQGDNELHLRTFITGTY 853
+ S+D T+ W V+ + T T + + D + + D + + T
Sbjct: 209 SASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKEC 268
Query: 854 LHPLKRHKAKVKCFCVAHDSS 874
L+ H+ V+C A +SS
Sbjct: 269 KAELREHEHVVECISWAPESS 289
Score = 52.4 bits (120), Expect = 1e-05
Identities = 35/141 (24%), Positives = 57/141 (40%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+V A ++W + T KGH+ S+ + + L + S D ++ +WD
Sbjct: 123 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 182
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
+ H V VA + N ++S D + + + G V HR V V+
Sbjct: 183 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRP 242
Query: 787 IQDGNIFITGSQDGTVCTWNV 807
QDG + + S D TV W V
Sbjct: 243 NQDGTLIASCSNDQTVRVWVV 263
Score = 52.0 bits (119), Expect = 2e-05
Identities = 58/310 (18%), Positives = 113/310 (36%), Gaps = 12/310 (3%)
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNV- 832
L HR VT V ++ ++ S+D T+ W+ E T+ G + D++ D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK-GHTDSVQDISFDHSG 162
Query: 833 -FLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLH 891
L + D + L F + + H V + + + D+ I ++ +
Sbjct: 163 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 892 SAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTK 951
+ ++T L+A+ N T+ + + + K R
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW-----VVATKECKAELREHEH 277
Query: 952 STTNITLL-QAEQSDLIPISCLEVSRDGQLGA---SGCARGLVRVWQLSTHRLQATLNGH 1007
I+ ++ S + + E + G+ G SG +++W +ST TL GH
Sbjct: 278 VVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGH 337
Query: 1008 IGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMS 1067
+ V F +LS ++D+T+ VW + T H + +L ++
Sbjct: 338 DNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVT 397
Query: 1068 SDRARNVHVW 1077
+ V VW
Sbjct: 398 GSVDQTVKVW 407
Score = 46.8 bits (106), Expect = 6e-04
Identities = 38/179 (21%), Positives = 71/179 (39%), Gaps = 20/179 (11%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
+ P+G H+V A ++W + + V TF GH + + ++ + + S D +V
Sbjct: 200 IMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVR 259
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRS--------------------LVISGGDDSA 759
VW + T K ++ EH V C++ S ++SG D
Sbjct: 260 VWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKT 319
Query: 760 VIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA 818
+ + + G + L H V V G ++ + D T+ W+ +N + T+ A
Sbjct: 320 IKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA 378
Score = 41.5 bits (93), Expect = 0.021
Identities = 26/98 (26%), Positives = 44/98 (44%)
Query: 708 YLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVD 767
+LL+GS D ++ +WD+ T ++ H V V ++S DD + + +
Sbjct: 310 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 369
Query: 768 GALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
+ L+ H VTS+ + +TGS D TV W
Sbjct: 370 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
Score = 34.3 bits (75), Expect = 3.3
Identities = 36/181 (19%), Positives = 73/181 (40%), Gaps = 4/181 (2%)
Query: 663 SGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWD 722
SG+ L + +LW + T GH ++ + + ++++ S D ++ +W+
Sbjct: 161 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 220
Query: 723 LHT-LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSV 781
+ T VKT H V V + +L+ S +D V + + +L H V
Sbjct: 221 VQTGYCVKT-FTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVV 279
Query: 782 TSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG-D 840
+ + + G+ + + L + + I ++DV+ + L+TL G D
Sbjct: 280 ECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVS-TGMCLMTLVGHD 338
Query: 841 N 841
N
Sbjct: 339 N 339
>L13385-1|AAA02880.1| 410|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 410
Score = 79.4 bits (187), Expect = 9e-14
Identities = 63/279 (22%), Positives = 114/279 (40%), Gaps = 25/279 (8%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR 1063
L+GH +T V F P +++S SED T+ VW T KGH+ ++Q + G+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 163
Query: 1064 RAMSSDRARNVHVWLVDSGIVLHSATGPS---ASIDVTLNMKYAVLSDGDNSVRIWSLAG 1120
S + +W + + G +S+ + N + V + D ++++W +
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
Query: 1121 GDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVT 1180
G + H E + D + + S D +++VW + + L H +V
Sbjct: 224 G---YCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 280
Query: 1181 CVA-------VSITNKTQ------------VVSGSWDCNLIVWDINTXXXXXXXXXXXXK 1221
C++ SI+ T ++SGS D + +WD++T
Sbjct: 281 CISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW 340
Query: 1222 VTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
V V G +SCA+DKTL +W+ K + + + H
Sbjct: 341 VRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAH 379
Score = 79.4 bits (187), Expect = 9e-14
Identities = 63/283 (22%), Positives = 117/283 (41%), Gaps = 27/283 (9%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
++VW T + TL GH + ++F + L+ S S D T+ +W T GH
Sbjct: 132 IKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGH 191
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLS- 1107
+ ++ +M +G +S+ R + + +W V +G + + TG + V N +++
Sbjct: 192 DHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 251
Query: 1108 -DGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQH------------------ 1148
D +VR+W +A + + R H + C + +S +
Sbjct: 252 CSNDQTVRVWVVATKECKAELR---EHEHVVECISWAPESSYSSISEATGSETKKSGKPG 308
Query: 1149 --VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+++GS D ++K+W + G LVGH + V V K ++S + D L VWD
Sbjct: 309 PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKF-ILSCADDKTLRVWDY 367
Query: 1207 NTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
VT + V+ + D+T+ +WE +
Sbjct: 368 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
Score = 54.8 bits (126), Expect = 2e-06
Identities = 40/201 (19%), Positives = 82/201 (40%), Gaps = 2/201 (0%)
Query: 675 DPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE 734
DP+ W I + + GH + + +++ SED ++ VWD T + +
Sbjct: 90 DPKEW-IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKG 148
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H V ++ + L+ S D + + + + H +V+SV ++ +G+ +
Sbjct: 149 HTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIV 208
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVP-IHIFDVTDDNVFLLTLQGDNELHLRTFITGTY 853
+ S+D T+ W V+ + T T + + D + + D + + T
Sbjct: 209 SASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKEC 268
Query: 854 LHPLKRHKAKVKCFCVAHDSS 874
L+ H+ V+C A +SS
Sbjct: 269 KAELREHEHVVECISWAPESS 289
Score = 52.4 bits (120), Expect = 1e-05
Identities = 35/141 (24%), Positives = 57/141 (40%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+V A ++W + T KGH+ S+ + + L + S D ++ +WD
Sbjct: 123 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 182
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
+ H V VA + N ++S D + + + G V HR V V+
Sbjct: 183 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRP 242
Query: 787 IQDGNIFITGSQDGTVCTWNV 807
QDG + + S D TV W V
Sbjct: 243 NQDGTLIASCSNDQTVRVWVV 263
Score = 52.0 bits (119), Expect = 2e-05
Identities = 58/310 (18%), Positives = 113/310 (36%), Gaps = 12/310 (3%)
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNV- 832
L HR VT V ++ ++ S+D T+ W+ E T+ G + D++ D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK-GHTDSVQDISFDHSG 162
Query: 833 -FLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLH 891
L + D + L F + + H V + + + D+ I ++ +
Sbjct: 163 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 892 SAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTK 951
+ ++T L+A+ N T+ + + + K R
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW-----VVATKECKAELREHEH 277
Query: 952 STTNITLL-QAEQSDLIPISCLEVSRDGQLGA---SGCARGLVRVWQLSTHRLQATLNGH 1007
I+ ++ S + + E + G+ G SG +++W +ST TL GH
Sbjct: 278 VVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGH 337
Query: 1008 IGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMS 1067
+ V F +LS ++D+T+ VW + T H + +L ++
Sbjct: 338 DNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVT 397
Query: 1068 SDRARNVHVW 1077
+ V VW
Sbjct: 398 GSVDQTVKVW 407
Score = 46.8 bits (106), Expect = 6e-04
Identities = 38/179 (21%), Positives = 71/179 (39%), Gaps = 20/179 (11%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
+ P+G H+V A ++W + + V TF GH + + ++ + + S D +V
Sbjct: 200 IMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVR 259
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRS--------------------LVISGGDDSA 759
VW + T K ++ EH V C++ S ++SG D
Sbjct: 260 VWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKT 319
Query: 760 VIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA 818
+ + + G + L H V V G ++ + D T+ W+ +N + T+ A
Sbjct: 320 IKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA 378
Score = 41.5 bits (93), Expect = 0.021
Identities = 26/98 (26%), Positives = 44/98 (44%)
Query: 708 YLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVD 767
+LL+GS D ++ +WD+ T ++ H V V ++S DD + + +
Sbjct: 310 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 369
Query: 768 GALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
+ L+ H VTS+ + +TGS D TV W
Sbjct: 370 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
Score = 34.3 bits (75), Expect = 3.3
Identities = 36/181 (19%), Positives = 73/181 (40%), Gaps = 4/181 (2%)
Query: 663 SGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWD 722
SG+ L + +LW + T GH ++ + + ++++ S D ++ +W+
Sbjct: 161 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 220
Query: 723 LHT-LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSV 781
+ T VKT H V V + +L+ S +D V + + +L H V
Sbjct: 221 VQTGYCVKT-FTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVV 279
Query: 782 TSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG-D 840
+ + + G+ + + L + + I ++DV+ + L+TL G D
Sbjct: 280 ECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVS-TGMCLMTLVGHD 338
Query: 841 N 841
N
Sbjct: 339 N 339
>EF011619-1|ABK41109.1| 478|Homo sapiens CDW9/WDR51B protein.
Length = 478
Score = 79.4 bits (187), Expect = 9e-14
Identities = 57/266 (21%), Positives = 103/266 (38%), Gaps = 11/266 (4%)
Query: 1000 LQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
L+ GH IT + SPN + + S D +++W ++ + Y GH + ++
Sbjct: 10 LERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFS 69
Query: 1060 SDGRRAMSSDRARNVHVWLVDSG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIW 1116
G S+ R R V +W+ D + T P S+D + + ++ + D S+++W
Sbjct: 70 PHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVW 129
Query: 1117 SLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHS 1176
S+ H + C + D + +V+ S D ++K+W Q + S
Sbjct: 130 SMY---RQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTN---KQCVNNFS 183
Query: 1177 DIVTCVAVSITNK--TQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIA 1234
D V N T + S D + VWD+ V C+ G
Sbjct: 184 DSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYL 243
Query: 1235 VSCAEDKTLIIWETKRGLALTSFSLH 1260
++ + D TL I + G + + H
Sbjct: 244 ITASSDGTLKILDLLEGRLIYTLQGH 269
Score = 73.3 bits (172), Expect = 6e-12
Identities = 60/283 (21%), Positives = 114/283 (40%), Gaps = 7/283 (2%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+ L++S +G+ A+ + +W H GH +T V FSP+ L+ S S
Sbjct: 21 ITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASR 80
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
DRTV +W +K H++ ++++ +DG+ ++ +++ VW + L+S
Sbjct: 81 DRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSL 140
Query: 1089 ---TGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
T + + + V D +++IW + SV A +
Sbjct: 141 YRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVD---FNPS 197
Query: 1146 SQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ + D ++KVW + KL Q HS V C++ + +++ S D L + D
Sbjct: 198 GTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFH-PSGNYLITASSDGTLKILD 256
Query: 1206 INTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWET 1248
+ V V + G + S D +++W T
Sbjct: 257 LLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRT 299
Score = 71.7 bits (168), Expect = 2e-11
Identities = 54/240 (22%), Positives = 91/240 (37%), Gaps = 3/240 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+Q +P G L A +LW K FK H+ + + + + Q+L T SED S
Sbjct: 66 VQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKS 125
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ VW ++ + H V C + L++S +D + I + V
Sbjct: 126 IKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDS 185
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLS--TVTAGVPIHIFDVTDDNVFLL 835
G V G + D TV W+V LL V +G ++ +L+
Sbjct: 186 VGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSG-GVNCISFHPSGNYLI 244
Query: 836 TLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQL 895
T D L + + G ++ L+ H V + A G AD ++ L+ + +L
Sbjct: 245 TASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDEL 304
Score = 66.1 bits (154), Expect = 9e-10
Identities = 67/304 (22%), Positives = 117/304 (38%), Gaps = 24/304 (7%)
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H A + + N + + D+ +++ + A + H+ VTSV+ GN+
Sbjct: 17 HKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLA 76
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTY 853
+ S+D TV W + S A P+ D + D FL T D + + + +
Sbjct: 77 SASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRF 136
Query: 854 LHPLKRHKAKVKCFCVAHDSSRVAVGCA-DQRIYLYSLHSAQLLRTXXXXXXXXXXXXXX 912
L+ L RH V+C + D R+ V C+ D+ I ++ + Q +
Sbjct: 137 LYSLYRHTHWVRCAKFSPDG-RLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFN 195
Query: 913 XXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCL 972
+A+ G+ T+ + N LLQ Q ++C+
Sbjct: 196 PSGTCIASAGSDQTVKVWDVRVN---------------------KLLQHYQVHSGGVNCI 234
Query: 973 EVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTV 1032
G + + G +++ L RL TL GH G + V+FS L SG D V
Sbjct: 235 SFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQV 294
Query: 1033 VVWQ 1036
++W+
Sbjct: 295 LLWR 298
Score = 63.7 bits (148), Expect = 5e-09
Identities = 50/276 (18%), Positives = 100/276 (36%), Gaps = 1/276 (0%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L L+P+G+ L A LW+ +++ + + GH + + + L + S D +
Sbjct: 24 LDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASRDRT 83
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V +W ++ H APV V + + + +D ++ + S+ + L H
Sbjct: 84 VRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRH 143
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIF-DVTDDNVFLLT 836
V K DG + ++ S+D T+ W+ N ++ + V F D + +
Sbjct: 144 THWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIAS 203
Query: 837 LQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
D + + L + H V C + + +D + + L +L+
Sbjct: 204 AGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLI 263
Query: 897 RTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHT 932
T L A+GG + + T
Sbjct: 264 YTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRT 299
Score = 60.5 bits (140), Expect = 4e-08
Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 6/174 (3%)
Query: 1094 SIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGS 1153
S+D++ N K + D + +W+ + R V H + +T + + + S
Sbjct: 23 SLDLSPNGKQLATASWDTFLMLWNFKPHARAY---RYVGHKDVVTSVQFSPHGNLLASAS 79
Query: 1154 MDMSLKVWKLDG-GKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXX 1212
D ++++W D GK S+ H+ V V S + + + S D ++ VW +
Sbjct: 80 RDRTVRLWIPDKRGKFSE-FKAHTAPVRSVDFSADGQF-LATASEDKSIKVWSMYRQRFL 137
Query: 1213 XXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLGF 1266
V C K + DG + VSC+EDKT+ IW+T + +FS V F
Sbjct: 138 YSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANF 191
Score = 53.6 bits (123), Expect = 5e-06
Identities = 36/157 (22%), Positives = 64/157 (40%), Gaps = 3/157 (1%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
P+ ++ S DGQ A+ ++VW + R +L H + C FSP+ L++S S
Sbjct: 104 PVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCS 163
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHS 1087
ED+T+ +W + + + G S+ + V VW V +L
Sbjct: 164 EDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQH 223
Query: 1088 ---ATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGG 1121
+G I + Y + + D +++I L G
Sbjct: 224 YQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEG 260
Score = 49.6 bits (113), Expect = 8e-05
Identities = 30/147 (20%), Positives = 59/147 (40%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R + + GQ L A ++W + +++ H+ + C + + + +++ SED
Sbjct: 106 RSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSED 165
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
++ +WD + + V + + + S G D V + + L+
Sbjct: 166 KTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQ 225
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTV 802
H G V + GN IT S DGT+
Sbjct: 226 VHSGGVNCISFHPSGNYLITASSDGTL 252
Score = 45.2 bits (102), Expect = 0.002
Identities = 29/118 (24%), Positives = 51/118 (43%)
Query: 690 FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRS 749
FKGH +I + ++ + L T S DT +++W+ A + + H V V + +
Sbjct: 14 FKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGN 73
Query: 750 LVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
L+ S D V + ++ H V SV DG T S+D ++ W++
Sbjct: 74 LLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSM 131
>BC064638-1|AAH64638.1| 410|Homo sapiens platelet-activating factor
acetylhydrolase, isoform Ib, alpha subunit 45kDa protein.
Length = 410
Score = 79.4 bits (187), Expect = 9e-14
Identities = 63/279 (22%), Positives = 114/279 (40%), Gaps = 25/279 (8%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR 1063
L+GH +T V F P +++S SED T+ VW T KGH+ ++Q + G+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 163
Query: 1064 RAMSSDRARNVHVWLVDSGIVLHSATGPS---ASIDVTLNMKYAVLSDGDNSVRIWSLAG 1120
S + +W + + G +S+ + N + V + D ++++W +
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
Query: 1121 GDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVT 1180
G + H E + D + + S D +++VW + + L H +V
Sbjct: 224 G---YCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 280
Query: 1181 CVA-------VSITNKTQ------------VVSGSWDCNLIVWDINTXXXXXXXXXXXXK 1221
C++ SI+ T ++SGS D + +WD++T
Sbjct: 281 CISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW 340
Query: 1222 VTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
V V G +SCA+DKTL +W+ K + + + H
Sbjct: 341 VRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAH 379
Score = 79.4 bits (187), Expect = 9e-14
Identities = 63/283 (22%), Positives = 117/283 (41%), Gaps = 27/283 (9%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
++VW T + TL GH + ++F + L+ S S D T+ +W T GH
Sbjct: 132 IKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGH 191
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLS- 1107
+ ++ +M +G +S+ R + + +W V +G + + TG + V N +++
Sbjct: 192 DHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 251
Query: 1108 -DGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQH------------------ 1148
D +VR+W +A + + R H + C + +S +
Sbjct: 252 CSNDQTVRVWVVATKECKAELR---EHEHVVECISWAPESSYSSISEATGSETKKSGKPG 308
Query: 1149 --VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+++GS D ++K+W + G LVGH + V V K ++S + D L VWD
Sbjct: 309 PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKF-ILSCADDKTLRVWDY 367
Query: 1207 NTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
VT + V+ + D+T+ +WE +
Sbjct: 368 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
Score = 54.8 bits (126), Expect = 2e-06
Identities = 40/201 (19%), Positives = 82/201 (40%), Gaps = 2/201 (0%)
Query: 675 DPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE 734
DP+ W I + + GH + + +++ SED ++ VWD T + +
Sbjct: 90 DPKEW-IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKG 148
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H V ++ + L+ S D + + + + H +V+SV ++ +G+ +
Sbjct: 149 HTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIV 208
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVP-IHIFDVTDDNVFLLTLQGDNELHLRTFITGTY 853
+ S+D T+ W V+ + T T + + D + + D + + T
Sbjct: 209 SASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKEC 268
Query: 854 LHPLKRHKAKVKCFCVAHDSS 874
L+ H+ V+C A +SS
Sbjct: 269 KAELREHEHVVECISWAPESS 289
Score = 52.4 bits (120), Expect = 1e-05
Identities = 35/141 (24%), Positives = 57/141 (40%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+V A ++W + T KGH+ S+ + + L + S D ++ +WD
Sbjct: 123 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 182
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
+ H V VA + N ++S D + + + G V HR V V+
Sbjct: 183 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRP 242
Query: 787 IQDGNIFITGSQDGTVCTWNV 807
QDG + + S D TV W V
Sbjct: 243 NQDGTLIASCSNDQTVRVWVV 263
Score = 52.0 bits (119), Expect = 2e-05
Identities = 58/310 (18%), Positives = 113/310 (36%), Gaps = 12/310 (3%)
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNV- 832
L HR VT V ++ ++ S+D T+ W+ E T+ G + D++ D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK-GHTDSVQDISFDHSG 162
Query: 833 -FLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLH 891
L + D + L F + + H V + + + D+ I ++ +
Sbjct: 163 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 892 SAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTK 951
+ ++T L+A+ N T+ + + + K R
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW-----VVATKECKAELREHEH 277
Query: 952 STTNITLL-QAEQSDLIPISCLEVSRDGQLGA---SGCARGLVRVWQLSTHRLQATLNGH 1007
I+ ++ S + + E + G+ G SG +++W +ST TL GH
Sbjct: 278 VVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGH 337
Query: 1008 IGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMS 1067
+ V F +LS ++D+T+ VW + T H + +L ++
Sbjct: 338 DNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVT 397
Query: 1068 SDRARNVHVW 1077
+ V VW
Sbjct: 398 GSVDQTVKVW 407
Score = 46.8 bits (106), Expect = 6e-04
Identities = 38/179 (21%), Positives = 71/179 (39%), Gaps = 20/179 (11%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
+ P+G H+V A ++W + + V TF GH + + ++ + + S D +V
Sbjct: 200 IMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVR 259
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRS--------------------LVISGGDDSA 759
VW + T K ++ EH V C++ S ++SG D
Sbjct: 260 VWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKT 319
Query: 760 VIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA 818
+ + + G + L H V V G ++ + D T+ W+ +N + T+ A
Sbjct: 320 IKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA 378
Score = 41.5 bits (93), Expect = 0.021
Identities = 26/98 (26%), Positives = 44/98 (44%)
Query: 708 YLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVD 767
+LL+GS D ++ +WD+ T ++ H V V ++S DD + + +
Sbjct: 310 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 369
Query: 768 GALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
+ L+ H VTS+ + +TGS D TV W
Sbjct: 370 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
Score = 34.3 bits (75), Expect = 3.3
Identities = 36/181 (19%), Positives = 73/181 (40%), Gaps = 4/181 (2%)
Query: 663 SGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWD 722
SG+ L + +LW + T GH ++ + + ++++ S D ++ +W+
Sbjct: 161 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 220
Query: 723 LHT-LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSV 781
+ T VKT H V V + +L+ S +D V + + +L H V
Sbjct: 221 VQTGYCVKT-FTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVV 279
Query: 782 TSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG-D 840
+ + + G+ + + L + + I ++DV+ + L+TL G D
Sbjct: 280 ECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVS-TGMCLMTLVGHD 338
Query: 841 N 841
N
Sbjct: 339 N 339
>BC026080-1|AAH26080.1| 478|Homo sapiens WD repeat domain 51B
protein.
Length = 478
Score = 79.4 bits (187), Expect = 9e-14
Identities = 57/266 (21%), Positives = 103/266 (38%), Gaps = 11/266 (4%)
Query: 1000 LQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
L+ GH IT + SPN + + S D +++W ++ + Y GH + ++
Sbjct: 10 LERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFS 69
Query: 1060 SDGRRAMSSDRARNVHVWLVDSG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIW 1116
G S+ R R V +W+ D + T P S+D + + ++ + D S+++W
Sbjct: 70 PHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVW 129
Query: 1117 SLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHS 1176
S+ H + C + D + +V+ S D ++K+W Q + S
Sbjct: 130 SMY---RQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTN---KQCVNNFS 183
Query: 1177 DIVTCVAVSITNK--TQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIA 1234
D V N T + S D + VWD+ V C+ G
Sbjct: 184 DSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYL 243
Query: 1235 VSCAEDKTLIIWETKRGLALTSFSLH 1260
++ + D TL I + G + + H
Sbjct: 244 ITASSDGTLKILDLLEGRLIYTLQGH 269
Score = 73.3 bits (172), Expect = 6e-12
Identities = 60/283 (21%), Positives = 114/283 (40%), Gaps = 7/283 (2%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+ L++S +G+ A+ + +W H GH +T V FSP+ L+ S S
Sbjct: 21 ITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASR 80
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
DRTV +W +K H++ ++++ +DG+ ++ +++ VW + L+S
Sbjct: 81 DRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSL 140
Query: 1089 ---TGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
T + + + V D +++IW + SV A +
Sbjct: 141 YRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVD---FNPS 197
Query: 1146 SQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ + D ++KVW + KL Q HS V C++ + +++ S D L + D
Sbjct: 198 GTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFH-PSGNYLITASSDGTLKILD 256
Query: 1206 INTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWET 1248
+ V V + G + S D +++W T
Sbjct: 257 LLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRT 299
Score = 71.7 bits (168), Expect = 2e-11
Identities = 54/240 (22%), Positives = 91/240 (37%), Gaps = 3/240 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+Q +P G L A +LW K FK H+ + + + + Q+L T SED S
Sbjct: 66 VQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKS 125
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ VW ++ + H V C + L++S +D + I + V
Sbjct: 126 IKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDS 185
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLS--TVTAGVPIHIFDVTDDNVFLL 835
G V G + D TV W+V LL V +G ++ +L+
Sbjct: 186 VGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSG-GVNCISFHPSGNYLI 244
Query: 836 TLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQL 895
T D L + + G ++ L+ H V + A G AD ++ L+ + +L
Sbjct: 245 TASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDEL 304
Score = 66.1 bits (154), Expect = 9e-10
Identities = 67/304 (22%), Positives = 117/304 (38%), Gaps = 24/304 (7%)
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H A + + N + + D+ +++ + A + H+ VTSV+ GN+
Sbjct: 17 HKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLA 76
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTY 853
+ S+D TV W + S A P+ D + D FL T D + + + +
Sbjct: 77 SASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRF 136
Query: 854 LHPLKRHKAKVKCFCVAHDSSRVAVGCA-DQRIYLYSLHSAQLLRTXXXXXXXXXXXXXX 912
L+ L RH V+C + D R+ V C+ D+ I ++ + Q +
Sbjct: 137 LYSLYRHTHWVRCAKFSPDG-RLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFN 195
Query: 913 XXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCL 972
+A+ G+ T+ + N LLQ Q ++C+
Sbjct: 196 PSGTCIASAGSDQTVKVWDVRVN---------------------KLLQHYQVHSGGVNCI 234
Query: 973 EVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTV 1032
G + + G +++ L RL TL GH G + V+FS L SG D V
Sbjct: 235 SFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQV 294
Query: 1033 VVWQ 1036
++W+
Sbjct: 295 LLWR 298
Score = 63.7 bits (148), Expect = 5e-09
Identities = 50/276 (18%), Positives = 100/276 (36%), Gaps = 1/276 (0%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L L+P+G+ L A LW+ +++ + + GH + + + L + S D +
Sbjct: 24 LDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASRDRT 83
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V +W ++ H APV V + + + +D ++ + S+ + L H
Sbjct: 84 VRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRH 143
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIF-DVTDDNVFLLT 836
V K DG + ++ S+D T+ W+ N ++ + V F D + +
Sbjct: 144 THWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIAS 203
Query: 837 LQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
D + + L + H V C + + +D + + L +L+
Sbjct: 204 AGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLI 263
Query: 897 RTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHT 932
T L A+GG + + T
Sbjct: 264 YTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRT 299
Score = 60.5 bits (140), Expect = 4e-08
Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 6/174 (3%)
Query: 1094 SIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGS 1153
S+D++ N K + D + +W+ + R V H + +T + + + S
Sbjct: 23 SLDLSPNGKQLATASWDTFLMLWNFKPHARAY---RYVGHKDVVTSVQFSPHGNLLASAS 79
Query: 1154 MDMSLKVWKLDG-GKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXX 1212
D ++++W D GK S+ H+ V V S + + + S D ++ VW +
Sbjct: 80 RDRTVRLWIPDKRGKFSE-FKAHTAPVRSVDFSADGQF-LATASEDKSIKVWSMYRQRFL 137
Query: 1213 XXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLGF 1266
V C K + DG + VSC+EDKT+ IW+T + +FS V F
Sbjct: 138 YSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANF 191
Score = 53.6 bits (123), Expect = 5e-06
Identities = 36/157 (22%), Positives = 64/157 (40%), Gaps = 3/157 (1%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
P+ ++ S DGQ A+ ++VW + R +L H + C FSP+ L++S S
Sbjct: 104 PVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCS 163
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHS 1087
ED+T+ +W + + + G S+ + V VW V +L
Sbjct: 164 EDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQH 223
Query: 1088 ---ATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGG 1121
+G I + Y + + D +++I L G
Sbjct: 224 YQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEG 260
Score = 49.6 bits (113), Expect = 8e-05
Identities = 30/147 (20%), Positives = 59/147 (40%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R + + GQ L A ++W + +++ H+ + C + + + +++ SED
Sbjct: 106 RSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSED 165
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
++ +WD + + V + + + S G D V + + L+
Sbjct: 166 KTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQ 225
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTV 802
H G V + GN IT S DGT+
Sbjct: 226 VHSGGVNCISFHPSGNYLITASSDGTL 252
Score = 45.2 bits (102), Expect = 0.002
Identities = 29/118 (24%), Positives = 51/118 (43%)
Query: 690 FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRS 749
FKGH +I + ++ + L T S DT +++W+ A + + H V V + +
Sbjct: 14 FKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGN 73
Query: 750 LVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
L+ S D V + ++ H V SV DG T S+D ++ W++
Sbjct: 74 LLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSM 131
>AK074772-1|BAC11198.1| 478|Homo sapiens protein ( Homo sapiens cDNA
FLJ90291 fis, clone NT2RP1001031, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 478
Score = 79.4 bits (187), Expect = 9e-14
Identities = 57/266 (21%), Positives = 103/266 (38%), Gaps = 11/266 (4%)
Query: 1000 LQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
L+ GH IT + SPN + + S D +++W ++ + Y GH + ++
Sbjct: 10 LERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFS 69
Query: 1060 SDGRRAMSSDRARNVHVWLVDSG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIW 1116
G S+ R R V +W+ D + T P S+D + + ++ + D S+++W
Sbjct: 70 PHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVW 129
Query: 1117 SLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHS 1176
S+ H + C + D + +V+ S D ++K+W Q + S
Sbjct: 130 SMY---RQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTN---KQCVNNFS 183
Query: 1177 DIVTCVAVSITNK--TQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIA 1234
D V N T + S D + VWD+ V C+ G
Sbjct: 184 DSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYL 243
Query: 1235 VSCAEDKTLIIWETKRGLALTSFSLH 1260
++ + D TL I + G + + H
Sbjct: 244 ITASSDGTLKILDLLEGRLIYTLQGH 269
Score = 73.3 bits (172), Expect = 6e-12
Identities = 60/283 (21%), Positives = 114/283 (40%), Gaps = 7/283 (2%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I+ L++S +G+ A+ + +W H GH +T V FSP+ L+ S S
Sbjct: 21 ITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASR 80
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
DRTV +W +K H++ ++++ +DG+ ++ +++ VW + L+S
Sbjct: 81 DRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSL 140
Query: 1089 ---TGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
T + + + V D +++IW + SV A +
Sbjct: 141 YRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVD---FNPS 197
Query: 1146 SQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ + D ++KVW + KL Q HS V C++ + +++ S D L + D
Sbjct: 198 GTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFH-PSGNYLITASSDGTLKILD 256
Query: 1206 INTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWET 1248
+ V V + G + S D +++W T
Sbjct: 257 LLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRT 299
Score = 71.7 bits (168), Expect = 2e-11
Identities = 54/240 (22%), Positives = 91/240 (37%), Gaps = 3/240 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+Q +P G L A +LW K FK H+ + + + + Q+L T SED S
Sbjct: 66 VQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKS 125
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ VW ++ + H V C + L++S +D + I + V
Sbjct: 126 IKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDS 185
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLS--TVTAGVPIHIFDVTDDNVFLL 835
G V G + D TV W+V LL V +G ++ +L+
Sbjct: 186 VGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSG-GVNCISFHPSGNYLI 244
Query: 836 TLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQL 895
T D L + + G ++ L+ H V + A G AD ++ L+ + +L
Sbjct: 245 TASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDEL 304
Score = 66.1 bits (154), Expect = 9e-10
Identities = 67/304 (22%), Positives = 117/304 (38%), Gaps = 24/304 (7%)
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H A + + N + + D+ +++ + A + H+ VTSV+ GN+
Sbjct: 17 HKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLA 76
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTY 853
+ S+D TV W + S A P+ D + D FL T D + + + +
Sbjct: 77 SASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRF 136
Query: 854 LHPLKRHKAKVKCFCVAHDSSRVAVGCA-DQRIYLYSLHSAQLLRTXXXXXXXXXXXXXX 912
L+ L RH V+C + D R+ V C+ D+ I ++ + Q +
Sbjct: 137 LYSLYRHTHWVRCAKFSPDG-RLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFN 195
Query: 913 XXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCL 972
+A+ G+ T+ + N LLQ Q ++C+
Sbjct: 196 PSGTCIASAGSDQTVKVWDVRVN---------------------KLLQHYQVHSGGVNCI 234
Query: 973 EVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTV 1032
G + + G +++ L RL TL GH G + V+FS L SG D V
Sbjct: 235 SFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQV 294
Query: 1033 VVWQ 1036
++W+
Sbjct: 295 LLWR 298
Score = 63.7 bits (148), Expect = 5e-09
Identities = 50/276 (18%), Positives = 100/276 (36%), Gaps = 1/276 (0%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L L+P+G+ L A LW+ +++ + + GH + + + L + S D +
Sbjct: 24 LDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASRDRT 83
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V +W ++ H APV V + + + +D ++ + S+ + L H
Sbjct: 84 VRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRH 143
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIF-DVTDDNVFLLT 836
V K DG + ++ S+D T+ W+ N ++ + V F D + +
Sbjct: 144 THWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIAS 203
Query: 837 LQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
D + + L + H V C + + +D + + L +L+
Sbjct: 204 AGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLI 263
Query: 897 RTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHT 932
T L A+GG + + T
Sbjct: 264 YTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRT 299
Score = 60.5 bits (140), Expect = 4e-08
Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 6/174 (3%)
Query: 1094 SIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGS 1153
S+D++ N K + D + +W+ + R V H + +T + + + S
Sbjct: 23 SLDLSPNGKQLATASWDTFLMLWNFKPHARAY---RYVGHKDVVTSVQFSPHGNLLASAS 79
Query: 1154 MDMSLKVWKLDG-GKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXX 1212
D ++++W D GK S+ H+ V V S + + + S D ++ VW +
Sbjct: 80 RDRTVRLWIPDKRGKFSE-FKAHTAPVRSVDFSADGQF-LATASEDKSIKVWSMYRQRFL 137
Query: 1213 XXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLGF 1266
V C K + DG + VSC+EDKT+ IW+T + +FS V F
Sbjct: 138 YSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANF 191
Score = 53.6 bits (123), Expect = 5e-06
Identities = 36/157 (22%), Positives = 64/157 (40%), Gaps = 3/157 (1%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
P+ ++ S DGQ A+ ++VW + R +L H + C FSP+ L++S S
Sbjct: 104 PVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCS 163
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHS 1087
ED+T+ +W + + + G S+ + V VW V +L
Sbjct: 164 EDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQH 223
Query: 1088 ---ATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGG 1121
+G I + Y + + D +++I L G
Sbjct: 224 YQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEG 260
Score = 49.6 bits (113), Expect = 8e-05
Identities = 30/147 (20%), Positives = 59/147 (40%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R + + GQ L A ++W + +++ H+ + C + + + +++ SED
Sbjct: 106 RSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSED 165
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
++ +WD + + V + + + S G D V + + L+
Sbjct: 166 KTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQ 225
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTV 802
H G V + GN IT S DGT+
Sbjct: 226 VHSGGVNCISFHPSGNYLITASSDGTL 252
Score = 45.2 bits (102), Expect = 0.002
Identities = 29/118 (24%), Positives = 51/118 (43%)
Query: 690 FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRS 749
FKGH +I + ++ + L T S DT +++W+ A + + H V V + +
Sbjct: 14 FKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGN 73
Query: 750 LVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
L+ S D V + ++ H V SV DG T S+D ++ W++
Sbjct: 74 LLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSM 131
>AF400434-1|AAK92483.1| 410|Homo sapiens platelet-activating factor
acetyl hydrolase isoform Ib alpha subunit protein.
Length = 410
Score = 79.4 bits (187), Expect = 9e-14
Identities = 63/279 (22%), Positives = 114/279 (40%), Gaps = 25/279 (8%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR 1063
L+GH +T V F P +++S SED T+ VW T KGH+ ++Q + G+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 163
Query: 1064 RAMSSDRARNVHVWLVDSGIVLHSATGPS---ASIDVTLNMKYAVLSDGDNSVRIWSLAG 1120
S + +W + + G +S+ + N + V + D ++++W +
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
Query: 1121 GDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVT 1180
G + H E + D + + S D +++VW + + L H +V
Sbjct: 224 G---YCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 280
Query: 1181 CVA-------VSITNKTQ------------VVSGSWDCNLIVWDINTXXXXXXXXXXXXK 1221
C++ SI+ T ++SGS D + +WD++T
Sbjct: 281 CISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW 340
Query: 1222 VTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
V V G +SCA+DKTL +W+ K + + + H
Sbjct: 341 VRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAH 379
Score = 79.4 bits (187), Expect = 9e-14
Identities = 63/283 (22%), Positives = 117/283 (41%), Gaps = 27/283 (9%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
++VW T + TL GH + ++F + L+ S S D T+ +W T GH
Sbjct: 132 IKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGH 191
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLS- 1107
+ ++ +M +G +S+ R + + +W V +G + + TG + V N +++
Sbjct: 192 DHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 251
Query: 1108 -DGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQH------------------ 1148
D +VR+W +A + + R H + C + +S +
Sbjct: 252 CSNDQTVRVWVVATKECKAELR---EHEHVVECISWAPESSYSSISEATGSETKKSGKPG 308
Query: 1149 --VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+++GS D ++K+W + G LVGH + V V K ++S + D L VWD
Sbjct: 309 PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKF-ILSCADDKTLRVWDY 367
Query: 1207 NTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
VT + V+ + D+T+ +WE +
Sbjct: 368 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
Score = 54.8 bits (126), Expect = 2e-06
Identities = 40/201 (19%), Positives = 82/201 (40%), Gaps = 2/201 (0%)
Query: 675 DPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE 734
DP+ W I + + GH + + +++ SED ++ VWD T + +
Sbjct: 90 DPKEW-IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKG 148
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H V ++ + L+ S D + + + + H +V+SV ++ +G+ +
Sbjct: 149 HTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIV 208
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVP-IHIFDVTDDNVFLLTLQGDNELHLRTFITGTY 853
+ S+D T+ W V+ + T T + + D + + D + + T
Sbjct: 209 SASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKEC 268
Query: 854 LHPLKRHKAKVKCFCVAHDSS 874
L+ H+ V+C A +SS
Sbjct: 269 KAELREHEHVVECISWAPESS 289
Score = 52.4 bits (120), Expect = 1e-05
Identities = 35/141 (24%), Positives = 57/141 (40%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+V A ++W + T KGH+ S+ + + L + S D ++ +WD
Sbjct: 123 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 182
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
+ H V VA + N ++S D + + + G V HR V V+
Sbjct: 183 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRP 242
Query: 787 IQDGNIFITGSQDGTVCTWNV 807
QDG + + S D TV W V
Sbjct: 243 NQDGTLIASCSNDQTVRVWVV 263
Score = 52.0 bits (119), Expect = 2e-05
Identities = 58/310 (18%), Positives = 113/310 (36%), Gaps = 12/310 (3%)
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNV- 832
L HR VT V ++ ++ S+D T+ W+ E T+ G + D++ D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK-GHTDSVQDISFDHSG 162
Query: 833 -FLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLH 891
L + D + L F + + H V + + + D+ I ++ +
Sbjct: 163 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 892 SAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTK 951
+ ++T L+A+ N T+ + + + K R
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW-----VVATKECKAELREHEH 277
Query: 952 STTNITLL-QAEQSDLIPISCLEVSRDGQLGA---SGCARGLVRVWQLSTHRLQATLNGH 1007
I+ ++ S + + E + G+ G SG +++W +ST TL GH
Sbjct: 278 VVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGH 337
Query: 1008 IGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMS 1067
+ V F +LS ++D+T+ VW + T H + +L ++
Sbjct: 338 DNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVT 397
Query: 1068 SDRARNVHVW 1077
+ V VW
Sbjct: 398 GSVDQTVKVW 407
Score = 46.8 bits (106), Expect = 6e-04
Identities = 38/179 (21%), Positives = 71/179 (39%), Gaps = 20/179 (11%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
+ P+G H+V A ++W + + V TF GH + + ++ + + S D +V
Sbjct: 200 IMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVR 259
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRS--------------------LVISGGDDSA 759
VW + T K ++ EH V C++ S ++SG D
Sbjct: 260 VWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKT 319
Query: 760 VIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA 818
+ + + G + L H V V G ++ + D T+ W+ +N + T+ A
Sbjct: 320 IKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA 378
Score = 41.5 bits (93), Expect = 0.021
Identities = 26/98 (26%), Positives = 44/98 (44%)
Query: 708 YLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVD 767
+LL+GS D ++ +WD+ T ++ H V V ++S DD + + +
Sbjct: 310 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 369
Query: 768 GALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
+ L+ H VTS+ + +TGS D TV W
Sbjct: 370 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
Score = 34.3 bits (75), Expect = 3.3
Identities = 36/181 (19%), Positives = 73/181 (40%), Gaps = 4/181 (2%)
Query: 663 SGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWD 722
SG+ L + +LW + T GH ++ + + ++++ S D ++ +W+
Sbjct: 161 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 220
Query: 723 LHT-LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSV 781
+ T VKT H V V + +L+ S +D V + + +L H V
Sbjct: 221 VQTGYCVKT-FTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVV 279
Query: 782 TSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG-D 840
+ + + G+ + + L + + I ++DV+ + L+TL G D
Sbjct: 280 ECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVS-TGMCLMTLVGHD 338
Query: 841 N 841
N
Sbjct: 339 N 339
>AF208837-1|AAL34972.1| 410|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 410
Score = 79.4 bits (187), Expect = 9e-14
Identities = 63/279 (22%), Positives = 114/279 (40%), Gaps = 25/279 (8%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR 1063
L+GH +T V F P +++S SED T+ VW T KGH+ ++Q + G+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 163
Query: 1064 RAMSSDRARNVHVWLVDSGIVLHSATGPS---ASIDVTLNMKYAVLSDGDNSVRIWSLAG 1120
S + +W + + G +S+ + N + V + D ++++W +
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
Query: 1121 GDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVT 1180
G + H E + D + + S D +++VW + + L H +V
Sbjct: 224 G---YCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 280
Query: 1181 CVA-------VSITNKTQ------------VVSGSWDCNLIVWDINTXXXXXXXXXXXXK 1221
C++ SI+ T ++SGS D + +WD++T
Sbjct: 281 CISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW 340
Query: 1222 VTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
V V G +SCA+DKTL +W+ K + + + H
Sbjct: 341 VRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAH 379
Score = 79.4 bits (187), Expect = 9e-14
Identities = 63/283 (22%), Positives = 117/283 (41%), Gaps = 27/283 (9%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
++VW T + TL GH + ++F + L+ S S D T+ +W T GH
Sbjct: 132 IKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGH 191
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLS- 1107
+ ++ +M +G +S+ R + + +W V +G + + TG + V N +++
Sbjct: 192 DHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 251
Query: 1108 -DGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQH------------------ 1148
D +VR+W +A + + R H + C + +S +
Sbjct: 252 CSNDQTVRVWVVATKECKAELR---EHEHVVECISWAPESSYSSISEATGSETKKSGKPG 308
Query: 1149 --VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+++GS D ++K+W + G LVGH + V V K ++S + D L VWD
Sbjct: 309 PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKF-ILSCADDKTLRVWDY 367
Query: 1207 NTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
VT + V+ + D+T+ +WE +
Sbjct: 368 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
Score = 54.8 bits (126), Expect = 2e-06
Identities = 40/201 (19%), Positives = 82/201 (40%), Gaps = 2/201 (0%)
Query: 675 DPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE 734
DP+ W I + + GH + + +++ SED ++ VWD T + +
Sbjct: 90 DPKEW-IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKG 148
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H V ++ + L+ S D + + + + H +V+SV ++ +G+ +
Sbjct: 149 HTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIV 208
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVP-IHIFDVTDDNVFLLTLQGDNELHLRTFITGTY 853
+ S+D T+ W V+ + T T + + D + + D + + T
Sbjct: 209 SASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKEC 268
Query: 854 LHPLKRHKAKVKCFCVAHDSS 874
L+ H+ V+C A +SS
Sbjct: 269 KAELREHEHVVECISWAPESS 289
Score = 52.4 bits (120), Expect = 1e-05
Identities = 35/141 (24%), Positives = 57/141 (40%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+V A ++W + T KGH+ S+ + + L + S D ++ +WD
Sbjct: 123 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 182
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
+ H V VA + N ++S D + + + G V HR V V+
Sbjct: 183 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRP 242
Query: 787 IQDGNIFITGSQDGTVCTWNV 807
QDG + + S D TV W V
Sbjct: 243 NQDGTLIASCSNDQTVRVWVV 263
Score = 52.0 bits (119), Expect = 2e-05
Identities = 58/310 (18%), Positives = 113/310 (36%), Gaps = 12/310 (3%)
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNV- 832
L HR VT V ++ ++ S+D T+ W+ E T+ G + D++ D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK-GHTDSVQDISFDHSG 162
Query: 833 -FLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLH 891
L + D + L F + + H V + + + D+ I ++ +
Sbjct: 163 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 892 SAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTK 951
+ ++T L+A+ N T+ + + + K R
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW-----VVATKECKAELREHEH 277
Query: 952 STTNITLL-QAEQSDLIPISCLEVSRDGQLGA---SGCARGLVRVWQLSTHRLQATLNGH 1007
I+ ++ S + + E + G+ G SG +++W +ST TL GH
Sbjct: 278 VVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGH 337
Query: 1008 IGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMS 1067
+ V F +LS ++D+T+ VW + T H + +L ++
Sbjct: 338 DNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVT 397
Query: 1068 SDRARNVHVW 1077
+ V VW
Sbjct: 398 GSVDQTVKVW 407
Score = 46.8 bits (106), Expect = 6e-04
Identities = 38/179 (21%), Positives = 71/179 (39%), Gaps = 20/179 (11%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
+ P+G H+V A ++W + + V TF GH + + ++ + + S D +V
Sbjct: 200 IMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVR 259
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRS--------------------LVISGGDDSA 759
VW + T K ++ EH V C++ S ++SG D
Sbjct: 260 VWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKT 319
Query: 760 VIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA 818
+ + + G + L H V V G ++ + D T+ W+ +N + T+ A
Sbjct: 320 IKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA 378
Score = 41.5 bits (93), Expect = 0.021
Identities = 26/98 (26%), Positives = 44/98 (44%)
Query: 708 YLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVD 767
+LL+GS D ++ +WD+ T ++ H V V ++S DD + + +
Sbjct: 310 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 369
Query: 768 GALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
+ L+ H VTS+ + +TGS D TV W
Sbjct: 370 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
Score = 34.3 bits (75), Expect = 3.3
Identities = 36/181 (19%), Positives = 73/181 (40%), Gaps = 4/181 (2%)
Query: 663 SGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWD 722
SG+ L + +LW + T GH ++ + + ++++ S D ++ +W+
Sbjct: 161 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 220
Query: 723 LHT-LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSV 781
+ T VKT H V V + +L+ S +D V + + +L H V
Sbjct: 221 VQTGYCVKT-FTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVV 279
Query: 782 TSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG-D 840
+ + + G+ + + L + + I ++DV+ + L+TL G D
Sbjct: 280 ECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVS-TGMCLMTLVGHD 338
Query: 841 N 841
N
Sbjct: 339 N 339
>M16538-1|AAA35922.1| 340|Homo sapiens protein ( Human
signal-transducing guanine nucleotide-binding regulatory
(G) protein beta subunit mRNA, complete cds. ).
Length = 340
Score = 78.6 bits (185), Expect = 2e-13
Identities = 57/238 (23%), Positives = 106/238 (44%), Gaps = 16/238 (6%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N ++ S S D T
Sbjct: 109 GNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + ++ + GHS + +L + +GR +S ++ +W V + + G +
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPNGRTFVSGACDASIKLWDVRDSMCRQTFIGHES 227
Query: 1094 SIDVTLNMK--YAVLSDGDNSV-RIWSLAGGDNSEDNRRSVSHAE---RITCFALTADSQ 1147
I+ YA + D++ R++ L ++ SH IT A + +
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDL----RADQELLMYSHDNIICGITSVAFSRSGR 283
Query: 1148 HVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
++ G D + +W G + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 284 LLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 340
Score = 67.7 bits (158), Expect = 3e-10
Identities = 49/198 (24%), Positives = 81/198 (40%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + GH G + ++ +PN +SG+
Sbjct: 146 LSCCRFLDDNQIITSS-GDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPNGRTFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR--RAMSSDRARNVHVWLVDSGIVLH 1086
D ++ +W + D+ T+ GH S I + +G S D + D ++++
Sbjct: 205 DASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V + +L G D + IW GD + H R++C +T
Sbjct: 265 SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 322 DDGMAVATGSWDSFLKIW 339
Score = 58.8 bits (136), Expect = 1e-07
Identities = 46/201 (22%), Positives = 81/201 (40%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T H V+ ++ N
Sbjct: 141 GHTGYLSC-CRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPNGRTF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NF 810
+SG D+++ + + D H + +V +G F TGS D T +++ +
Sbjct: 200 VSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQ 259
Query: 811 TLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
LL + I V L L G ++ + + + G L H +V C
Sbjct: 260 ELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLKIWN 340
Score = 58.4 bits (135), Expect = 2e-07
Identities = 51/261 (19%), Positives = 101/261 (38%), Gaps = 12/261 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSATGPSASIDVT----LNMKYAVLSDGDNS 1112
G D +++ G V S P + ++ L+ + S GD +
Sbjct: 106 AXSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + G + H+ + +L + + V+G+ D S+K+W + Q
Sbjct: 166 CALWDIETGQQTVG---FAGHSGDVMSLSLAPNGRTFVSGACDASIKLWDVRDSMCRQTF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
+GH + VA N +GS D ++D+ +T V +
Sbjct: 223 IGHESDINAVAF-FPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRS 281
Query: 1231 GTIAVSCAEDKTLIIWETKRG 1251
G + ++ +D IW+ +G
Sbjct: 282 GRLLLAGYDDFNCNIWDAMKG 302
Score = 54.4 bits (125), Expect = 3e-06
Identities = 44/180 (24%), Positives = 78/180 (43%), Gaps = 7/180 (3%)
Query: 672 SAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK 729
S+GD LW I + + F GHSG ++ + + + ++G+ D S+ +WD+ +
Sbjct: 160 SSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPNGRTFVSGACDASIKLWDVRDSMCR 219
Query: 730 TKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSVKVI 787
+ H + + VA N +G DD+ + L D L+ D+ +TSV
Sbjct: 220 QTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFS 279
Query: 788 QDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNELHL 845
+ G + + G D W+ + V AG + VTDD + + T D+ L +
Sbjct: 280 RSGRLLLAGYDDFNCNIWDAMKGD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 338
Score = 52.4 bits (120), Expect = 1e-05
Identities = 43/218 (19%), Positives = 93/218 (42%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDV---TLNM 1101
T +GH + I + +D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAXSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
+ DN I+SL + N +R H ++C D+Q ++T S D + +
Sbjct: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ G+ + GHS V ++++ +T VSG+ D ++ +WD+
Sbjct: 169 WDIETGQQTVGFAGHSGDVMSLSLAPNGRT-FVSGACDASIKLWDVRDSMCRQTFIGHES 227
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ V +G + ++D T +++ + L +S
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYS 265
Score = 52.0 bits (119), Expect = 2e-05
Identities = 60/292 (20%), Positives = 114/292 (39%), Gaps = 18/292 (6%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC N V
Sbjct: 55 LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAXSGNF-VA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDT-TCALWDIE 172
Query: 1081 SG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+G + +G S+ + N + V D S+++W + +S + + H I
Sbjct: 173 TGQQTVGFAGHSGDVMSLSLAPNGRTFVSGACDASIKLWDVR---DSMCRQTFIGHESDI 229
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVS 1194
A + TGS D + +++ L + ++ H +I+ T VA S + + +++
Sbjct: 230 NAVAFFPNGYAFTTGSDDATCRLFDLRADQ-ELLMYSHDNIICGITSVAFSRSGRL-LLA 287
Query: 1195 GSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
G D N +WD +V+C+ VT DG + + D L IW
Sbjct: 288 GYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 52.0 bits (119), Expect = 2e-05
Identities = 41/152 (26%), Positives = 62/152 (40%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP+G+ V +LW + + TF GH I + TGS+D +
Sbjct: 190 LSLAPNGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDAT 249
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + + H I + VA + L+++G DD I + G L
Sbjct: 250 CRLFDLRA-DQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVL 308
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 48.4 bits (110), Expect = 2e-04
Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 5/124 (4%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAXSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I SL +G + +L H G ++ + + D I IT S D T
Sbjct: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQI-ITSSGDTTCAL 168
Query: 805 WNVE 808
W++E
Sbjct: 169 WDIE 172
Score = 48.4 bits (110), Expect = 2e-04
Identities = 30/147 (20%), Positives = 60/147 (40%), Gaps = 5/147 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +KVH S ++ ++ G D ++ L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAXSGNFVACGGLDNICSIYSLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + ++ S GD + + + G H G V
Sbjct: 130 EGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCA-LWDIETGQQTVGFAGHSGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVEN 809
S+ + +G F++G+ D ++ W+V +
Sbjct: 189 SLSLAPNGRTFVSGACDASIKLWDVRD 215
Score = 43.2 bits (97), Expect = 0.007
Identities = 30/128 (23%), Positives = 55/128 (42%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 101 MTC-AYAXSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDN--QI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
++ S D +WDI T V + + +G VS A D ++ +W+ + +
Sbjct: 158 ITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPNGRTFVSGACDASIKLWDVRDSM 217
Query: 1253 ALTSFSLH 1260
+F H
Sbjct: 218 CRQTFIGH 225
Score = 36.3 bits (80), Expect = 0.81
Identities = 54/306 (17%), Positives = 103/306 (33%), Gaps = 25/306 (8%)
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H+A + + + L++S D +II V + V + GN
Sbjct: 54 HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAXSGNFVA 113
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVT-----DDNVFLLTLQGDNELHLRTFI 849
G D ++++ V+ +P H ++ DDN ++T GD L
Sbjct: 114 CGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCALWDIE 172
Query: 850 TGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXX 909
TG H V +A + G D I L+ + + +T
Sbjct: 173 TGQQTVGFAGHSGDVMSLSLAPNGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAV 232
Query: 910 XXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPI 969
+ G + T F + R +++ L+ + + + I
Sbjct: 233 AFFPNGYAFTTGSDDATCRLF-------DLRADQEL------------LMYSHDNIICGI 273
Query: 970 SCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSED 1029
+ + SR G+L +G +W L GH ++C+ + + + V +GS D
Sbjct: 274 TSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
Query: 1030 RTVVVW 1035
+ +W
Sbjct: 334 SFLKIW 339
>AJ243003-1|CAB55579.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 78.6 bits (185), Expect = 2e-13
Identities = 97/460 (21%), Positives = 178/460 (38%), Gaps = 37/460 (8%)
Query: 828 TDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRV--AVGCADQRI 885
TDD F+ T D ++ + +TG +H H +V C A+ S + A G +D +
Sbjct: 667 TDDR-FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFANSSHHLLLATGSSDCFL 725
Query: 886 YLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQM 945
L+ L+ + T LLA S + L + T
Sbjct: 726 KLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLA---------SCSADGTLKLWDATSAN 776
Query: 946 KRRQTKSTTNITLLQAEQSDL-IPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATL 1004
+R+ L+ Q D+ + + C S DG A+ + +W + A
Sbjct: 777 ERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGAR-IMVAAKNKIFLWNTDSRSKVADC 835
Query: 1005 NGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQ---LADNSPSLTYKGHSSAIQTLLMMSD 1061
GH+ + V FSP+ L+ S+D+T+ +W+ + NS + + Q +M
Sbjct: 836 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVM-- 893
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGG 1121
++ D R + + +G + + + ++ +++Y D + ++ I L
Sbjct: 894 ---VLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELV-- 948
Query: 1122 DNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTC 1181
N+ + H + + TAD + +++ S D ++VW K L GH + T
Sbjct: 949 -NNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCI-FLRGHQE--TV 1004
Query: 1182 VAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDK 1241
+ ++++S S+D + VW+I T V ++ D T S + DK
Sbjct: 1005 KDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADK 1064
Query: 1242 TLIIWETKRGLALTSFSLHVPLLGFQITSDCARVVVHLLD 1281
T IW SF L +PL + + C R +D
Sbjct: 1065 TAKIW---------SFDLLLPLHELRGHNGCVRCSAFSVD 1095
Score = 63.7 bits (148), Expect = 5e-09
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 1/147 (0%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKT 1190
+H + + C A + D + + T S+D +K+W G+L HS+ V C + ++
Sbjct: 655 AHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFANSSHHL 714
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
+ +GS DC L +WD+N V + + D + SC+ D TL +W+
Sbjct: 715 LLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATS 774
Query: 1251 GLALTSFSLHVPLLGFQITSDCARVVV 1277
S ++ L + + V+V
Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIV 801
Score = 53.6 bits (123), Expect = 5e-06
Identities = 42/202 (20%), Positives = 91/202 (45%), Gaps = 5/202 (2%)
Query: 697 ILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGD 756
+ C C++ QY+ G E+ ++ + +L + +H V + + +IS D
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 757 DSAVIITSL-VDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLST 815
D+ + + + +D + L H+ +V +++++ + ++ S DGTV WN+
Sbjct: 981 DAEIQVWNWQLDKCIF--LRGHQETVKDFRLLKNSRL-LSWSFDGTVKVWNIITGNKEKD 1037
Query: 816 -VTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSS 874
V + D++ D + D + +F LH L+ H V+C + DS+
Sbjct: 1038 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST 1097
Query: 875 RVAVGCADQRIYLYSLHSAQLL 896
+A G + I ++++ + +LL
Sbjct: 1098 LLATGDDNGEIRIWNVSNGELL 1119
Score = 52.0 bits (119), Expect = 2e-05
Identities = 44/205 (21%), Positives = 86/205 (41%), Gaps = 12/205 (5%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC +S Q A G G + + +L +R+ + H + + F+ + ++S S+
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSG-----I 1083
D + VW + + +GH ++ ++ + R +S V VW + +G
Sbjct: 981 DAEIQVWNWQLDK-CIFLRGHQETVKDFRLLKNSR-LLSWSFDGTVKVWNIITGNKEKDF 1038
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
V H T S D++ + + D + +IWS D H + C A +
Sbjct: 1039 VCHQGT--VLSCDISHDATKFSSTSADKTAKIWSF---DLLLPLHELRGHNGCVRCSAFS 1093
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKL 1168
DS + TG + +++W + G+L
Sbjct: 1094 VDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 49.6 bits (113), Expect = 8e-05
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 10/142 (7%)
Query: 674 GDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKIL 733
G ++W+I++ +K F H G++L ++ ++ + S D + +W L ++
Sbjct: 1022 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1081
Query: 734 EHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALV---TKLDH-----HRGSVTSVK 785
H V C A V+ +L+ +G D+ + I ++ +G L+ L H G VT +
Sbjct: 1082 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1141
Query: 786 VIQDGNIFITGSQDGTVCTWNV 807
DG + I S G + WNV
Sbjct: 1142 FSPDGKMLI--SAGGYIKWWNV 1161
Score = 44.8 bits (101), Expect = 0.002
Identities = 32/145 (22%), Positives = 58/145 (40%), Gaps = 2/145 (1%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
GQ + + Q++ + K+ K H +LC + + +++ T S D V +W+
Sbjct: 627 GQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNS 686
Query: 724 HTLAVKTKILEHIAPVLC--VAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSV 781
T + EH V C A + L+ +G D + + L + H SV
Sbjct: 687 MTGELVHTYDEHSEQVNCCHFANSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSV 746
Query: 782 TSVKVIQDGNIFITGSQDGTVCTWN 806
+ D + + S DGT+ W+
Sbjct: 747 NHCRFSPDDKLLASCSADGTLKLWD 771
Score = 44.0 bits (99), Expect = 0.004
Identities = 49/272 (18%), Positives = 103/272 (37%), Gaps = 23/272 (8%)
Query: 997 THRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTL 1056
T+ + + H + FS + + S D+T+ V++ L K H +
Sbjct: 604 TNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCC 663
Query: 1057 LMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVT--LNMKYAVL---SDGDN 1111
+D R + + V +W +G ++H+ S ++ N + +L D
Sbjct: 664 AFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFANSSHHLLLATGSSDC 723
Query: 1112 SVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGG----- 1166
+++W L + E H + + D + + + S D +LK+W
Sbjct: 724 FLKLWDL---NQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKS 780
Query: 1167 -KLSQVLVGHSD-------IVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXX 1218
+ Q + D IV C + S +V+ + +W+ ++
Sbjct: 781 INVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAK--NKIFLWNTDSRSKVADCRGH 838
Query: 1219 XXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
V V + DG+ ++ ++D+T+ +WETK+
Sbjct: 839 LSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK 870
Score = 42.3 bits (95), Expect = 0.012
Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 9/147 (6%)
Query: 988 GLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYK 1047
G V+VW + T + H G + S + S S D+T +W P +
Sbjct: 1022 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1081
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH---------SATGPSASIDVT 1098
GH+ ++ D + D + +W V +G +LH +AT D+
Sbjct: 1082 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1141
Query: 1099 LNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+ +L ++ W++ G++S+
Sbjct: 1142 FSPDGKMLISAGGYIKWWNVVTGESSQ 1168
Score = 41.1 bits (92), Expect = 0.028
Identities = 40/199 (20%), Positives = 79/199 (39%), Gaps = 7/199 (3%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
L+P Q++ G ++ +++N + H ++ + T + + L++ S+D +
Sbjct: 926 LSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQ 985
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
VW+ K L + ++ S ++S D V + +++ G H+G
Sbjct: 986 VWNWQ--LDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1043
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV---TAGVPIHIFDVTDDNVFLLT 836
+V S + D F + S D T W+ + L + V F V D+ L T
Sbjct: 1044 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSV--DSTLLAT 1101
Query: 837 LQGDNELHLRTFITGTYLH 855
+ E+ + G LH
Sbjct: 1102 GDDNGEIRIWNVSNGELLH 1120
Score = 40.3 bits (90), Expect = 0.050
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 3/104 (2%)
Query: 951 KSTTNIT-LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIG 1009
K+ TN++ L+ +D + +C S DGQ AS A ++V++ T + H
Sbjct: 601 KNITNLSRLVVRPHTDAVYHACF--SEDGQRIASCGADKTLQVFKAETGEKLLEIKAHED 658
Query: 1010 HITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
+ C FS ++ + + S D+ V +W TY HS +
Sbjct: 659 EVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQV 702
Score = 37.5 bits (83), Expect = 0.35
Identities = 26/118 (22%), Positives = 49/118 (41%)
Query: 918 LAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRD 977
+ A + V +F T+D + + T + E S+ + S
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFANSSH 712
Query: 978 GQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVW 1035
L A+G + +++W L+ + T+ GH + FSP++ L+ S S D T+ +W
Sbjct: 713 HLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 770
Score = 35.1 bits (77), Expect = 1.9
Identities = 26/117 (22%), Positives = 47/117 (40%), Gaps = 2/117 (1%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ ++ C + + Q + + D ++ V+ T +I H VLC A + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
+ D V I + + G LV D H V + + TGS D + W++
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFANSSHHLLLATGSSDCFLKLWDL 730
>BC000873-1|AAH00873.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 4 protein.
Length = 340
Score = 78.2 bits (184), Expect = 2e-13
Identities = 61/238 (25%), Positives = 106/238 (44%), Gaps = 16/238 (6%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F ++ +V S S D T
Sbjct: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + + T+ GHS + +L + D R +S + +W + G+ S TG +
Sbjct: 168 LWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVS 227
Query: 1094 SIDVTLNMK--YAVLSDGDNSV-RIWSLAGGDNSEDNRRSVSHAE---RITCFALTADSQ 1147
I+ YA + D++ R++ L ++ SH IT A + +
Sbjct: 228 DINAVSFFPNGYAFATGSDDATCRLFDL----RADQELLLYSHDNIICGITSVAFSKSGR 283
Query: 1148 HVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
++ G D + VW G + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 284 LLLAGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLRIWN 340
Score = 66.1 bits (154), Expect = 9e-10
Identities = 50/198 (25%), Positives = 82/198 (41%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + T GH G + ++ SP+ +SG+
Sbjct: 146 LSCCRFLDDSQIVTSS-GDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRR-AMSSDRAR-NVHVWLVDSGIVLH 1086
D + +W + D ++ GH S I + +G A SD A + D ++L+
Sbjct: 205 DASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V + +L G D + +W GD + H R++C +T
Sbjct: 265 SHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D L++W
Sbjct: 322 DDGMAVATGSWDSFLRIW 339
Score = 62.1 bits (144), Expect = 1e-08
Identities = 49/201 (24%), Positives = 83/201 (41%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C +SQ ++T S DT+ +WD+ T T H V+ ++ +
Sbjct: 141 GHTGYLSCCRFLDDSQ-IVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NF 810
+SG D++ + + DG H + +V +G F TGS D T +++ +
Sbjct: 200 VSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQ 259
Query: 811 TLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFIT--GTYLHPLKRHKAKVKCFC 868
LL + I V L L G ++ + + T G L H +V C
Sbjct: 260 ELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLRIWN 340
Score = 59.3 bits (137), Expect = 1e-07
Identities = 52/261 (19%), Positives = 103/261 (39%), Gaps = 12/261 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSATGPSASIDVT----LNMKYAVLSDGDNS 1112
G D +++ G V S P + ++ L+ V S GD +
Sbjct: 106 APSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + + ++ H+ + +L+ D + V+G+ D S K+W + G Q
Sbjct: 166 CALWDI---ETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
GH + V+ N +GS D ++D+ +T V +
Sbjct: 223 TGHVSDINAVSF-FPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKS 281
Query: 1231 GTIAVSCAEDKTLIIWETKRG 1251
G + ++ +D +W+T +G
Sbjct: 282 GRLLLAGYDDFNCNVWDTLKG 302
Score = 56.4 bits (130), Expect = 7e-07
Identities = 44/183 (24%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Query: 669 LAPSAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+ S+GD LW I + + TF GHSG ++ + ++ + + ++G+ D S +WD+
Sbjct: 157 IVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDG 216
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSV 784
+ H++ + V+ N +G DD+ + L D L+ D+ +TSV
Sbjct: 217 MCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSV 276
Query: 785 KVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNE 842
+ G + + G D W+ + V AG + VTDD + + T D+
Sbjct: 277 AFSKSGRLLLAGYDDFNCNVWDTLKGD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSF 335
Query: 843 LHL 845
L +
Sbjct: 336 LRI 338
Score = 53.6 bits (123), Expect = 5e-06
Identities = 63/292 (21%), Positives = 118/292 (40%), Gaps = 18/292 (6%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCA-YAPSGNYVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDT-TCALWDIE 172
Query: 1081 SGIVLHSATGPSA---SIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+ + TG S S+ ++ +M+ V D S ++W + G + VS +
Sbjct: 173 TAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAV 232
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVS 1194
+ F + TGS D + +++ L + +L H +I+ T VA S + + +++
Sbjct: 233 SFFP---NGYAFATGSDDATCRLFDLRADQ-ELLLYSHDNIICGITSVAFSKSGRL-LLA 287
Query: 1195 GSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
G D N VWD +V+C+ VT DG + + D L IW
Sbjct: 288 GYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIW 339
Score = 51.2 bits (117), Expect = 3e-05
Identities = 46/218 (21%), Positives = 90/218 (41%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
Y DN I++L + N +R H ++C DSQ +VT S D + +
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQ-IVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ + + GHS V +++S +T VSG+ D + +WDI
Sbjct: 169 WDIETAQQTTTFTGHSGDVMSLSLSPDMRT-FVSGACDASSKLWDIRDGMCRQSFTGHVS 227
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ V +G + ++D T +++ + L +S
Sbjct: 228 DINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYS 265
Score = 49.2 bits (112), Expect = 1e-04
Identities = 33/129 (25%), Positives = 59/129 (45%), Gaps = 7/129 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A +V G +D ++ L +G ++S+ L GH+ ++C + +Q+
Sbjct: 101 MTC-AYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCR--FLDDSQI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
V+ S D +WDI T V + ++ D VS A D + +W+ + G+
Sbjct: 158 VTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGM 217
Query: 1253 ALTSFSLHV 1261
SF+ HV
Sbjct: 218 CRQSFTGHV 226
Score = 47.6 bits (108), Expect = 3e-04
Identities = 36/133 (27%), Positives = 62/133 (46%), Gaps = 5/133 (3%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D I +T S D T
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVT 817
W++E +T T
Sbjct: 169 WDIETAQQTTTFT 181
Score = 46.0 bits (104), Expect = 0.001
Identities = 38/152 (25%), Positives = 59/152 (38%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L L+P + V +LW I +F GH I + TGS+D +
Sbjct: 190 LSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDAT 249
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + + H I + VA + L+++G DD + + G L
Sbjct: 250 CRLFDLRA-DQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVL 308
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
Score = 44.8 bits (101), Expect = 0.002
Identities = 30/147 (20%), Positives = 59/147 (40%), Gaps = 5/147 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +K+H S ++ Y+ G D +++L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + +V S GD + + + T H G V
Sbjct: 130 EGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTTCA-LWDIETAQQTTTFTGHSGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVEN 809
S+ + D F++G+ D + W++ +
Sbjct: 189 SLSLSPDMRTFVSGACDASSKLWDIRD 215
>AF300648-1|AAG18442.1| 340|Homo sapiens guanine nucleotide binding
protein beta subunit 4 protein.
Length = 340
Score = 78.2 bits (184), Expect = 2e-13
Identities = 61/238 (25%), Positives = 106/238 (44%), Gaps = 16/238 (6%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F ++ +V S S D T
Sbjct: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + + T+ GHS + +L + D R +S + +W + G+ S TG +
Sbjct: 168 LWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVS 227
Query: 1094 SIDVTLNMK--YAVLSDGDNSV-RIWSLAGGDNSEDNRRSVSHAE---RITCFALTADSQ 1147
I+ YA + D++ R++ L ++ SH IT A + +
Sbjct: 228 DINAVSFFPNGYAFATGSDDATCRLFDL----RADQELLLYSHDNIICGITSVAFSKSGR 283
Query: 1148 HVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
++ G D + VW G + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 284 LLLAGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLRIWN 340
Score = 66.1 bits (154), Expect = 9e-10
Identities = 50/198 (25%), Positives = 82/198 (41%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + T GH G + ++ SP+ +SG+
Sbjct: 146 LSCCRFLDDSQIVTSS-GDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRR-AMSSDRAR-NVHVWLVDSGIVLH 1086
D + +W + D ++ GH S I + +G A SD A + D ++L+
Sbjct: 205 DASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V + +L G D + +W GD + H R++C +T
Sbjct: 265 SHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D L++W
Sbjct: 322 DDGMAVATGSWDSFLRIW 339
Score = 62.1 bits (144), Expect = 1e-08
Identities = 49/201 (24%), Positives = 83/201 (41%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C +SQ ++T S DT+ +WD+ T T H V+ ++ +
Sbjct: 141 GHTGYLSCCRFLDDSQ-IVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NF 810
+SG D++ + + DG H + +V +G F TGS D T +++ +
Sbjct: 200 VSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQ 259
Query: 811 TLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFIT--GTYLHPLKRHKAKVKCFC 868
LL + I V L L G ++ + + T G L H +V C
Sbjct: 260 ELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLRIWN 340
Score = 59.3 bits (137), Expect = 1e-07
Identities = 52/261 (19%), Positives = 103/261 (39%), Gaps = 12/261 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSATGPSASIDVT----LNMKYAVLSDGDNS 1112
G D +++ G V S P + ++ L+ V S GD +
Sbjct: 106 APSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + + ++ H+ + +L+ D + V+G+ D S K+W + G Q
Sbjct: 166 CALWDI---ETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
GH + V+ N +GS D ++D+ +T V +
Sbjct: 223 TGHVSDINAVSF-FPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKS 281
Query: 1231 GTIAVSCAEDKTLIIWETKRG 1251
G + ++ +D +W+T +G
Sbjct: 282 GRLLLAGYDDFNCNVWDTLKG 302
Score = 56.4 bits (130), Expect = 7e-07
Identities = 44/183 (24%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Query: 669 LAPSAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+ S+GD LW I + + TF GHSG ++ + ++ + + ++G+ D S +WD+
Sbjct: 157 IVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDG 216
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSV 784
+ H++ + V+ N +G DD+ + L D L+ D+ +TSV
Sbjct: 217 MCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSV 276
Query: 785 KVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNE 842
+ G + + G D W+ + V AG + VTDD + + T D+
Sbjct: 277 AFSKSGRLLLAGYDDFNCNVWDTLKGD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSF 335
Query: 843 LHL 845
L +
Sbjct: 336 LRI 338
Score = 53.6 bits (123), Expect = 5e-06
Identities = 63/292 (21%), Positives = 118/292 (40%), Gaps = 18/292 (6%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCA-YAPSGNYVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDT-TCALWDIE 172
Query: 1081 SGIVLHSATGPSA---SIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+ + TG S S+ ++ +M+ V D S ++W + G + VS +
Sbjct: 173 TAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAV 232
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVS 1194
+ F + TGS D + +++ L + +L H +I+ T VA S + + +++
Sbjct: 233 SFFP---NGYAFATGSDDATCRLFDLRADQ-ELLLYSHDNIICGITSVAFSKSGRL-LLA 287
Query: 1195 GSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
G D N VWD +V+C+ VT DG + + D L IW
Sbjct: 288 GYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIW 339
Score = 51.2 bits (117), Expect = 3e-05
Identities = 46/218 (21%), Positives = 90/218 (41%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
Y DN I++L + N +R H ++C DSQ +VT S D + +
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQ-IVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ + + GHS V +++S +T VSG+ D + +WDI
Sbjct: 169 WDIETAQQTTTFTGHSGDVMSLSLSPDMRT-FVSGACDASSKLWDIRDGMCRQSFTGHVS 227
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ V +G + ++D T +++ + L +S
Sbjct: 228 DINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYS 265
Score = 49.2 bits (112), Expect = 1e-04
Identities = 33/129 (25%), Positives = 59/129 (45%), Gaps = 7/129 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A +V G +D ++ L +G ++S+ L GH+ ++C + +Q+
Sbjct: 101 MTC-AYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCR--FLDDSQI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
V+ S D +WDI T V + ++ D VS A D + +W+ + G+
Sbjct: 158 VTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGM 217
Query: 1253 ALTSFSLHV 1261
SF+ HV
Sbjct: 218 CRQSFTGHV 226
Score = 47.6 bits (108), Expect = 3e-04
Identities = 36/133 (27%), Positives = 62/133 (46%), Gaps = 5/133 (3%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D I +T S D T
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVT 817
W++E +T T
Sbjct: 169 WDIETAQQTTTFT 181
Score = 46.0 bits (104), Expect = 0.001
Identities = 38/152 (25%), Positives = 59/152 (38%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L L+P + V +LW I +F GH I + TGS+D +
Sbjct: 190 LSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDAT 249
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + + H I + VA + L+++G DD + + G L
Sbjct: 250 CRLFDLRA-DQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVL 308
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
Score = 44.8 bits (101), Expect = 0.002
Identities = 30/147 (20%), Positives = 59/147 (40%), Gaps = 5/147 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +K+H S ++ Y+ G D +++L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + +V S GD + + + T H G V
Sbjct: 130 EGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTTCA-LWDIETAQQTTTFTGHSGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVEN 809
S+ + D F++G+ D + W++ +
Sbjct: 189 SLSLSPDMRTFVSGACDASSKLWDIRD 215
>AB209173-1|BAD92410.1| 832|Homo sapiens transducin beta-like 3
variant protein.
Length = 832
Score = 78.2 bits (184), Expect = 2e-13
Identities = 84/362 (23%), Positives = 142/362 (39%), Gaps = 33/362 (9%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPN--NLLVLS 1025
P++ + L A+G G VRVW + H G G + V F P+ LL+ S
Sbjct: 135 PVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFS 194
Query: 1026 GSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW-------- 1077
+ D + VW L D S H SA+ +L +DG +SS R + +W
Sbjct: 195 SATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQAT 254
Query: 1078 -------LVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
V++ ++L P + + V Y + + ++R+W A G +
Sbjct: 255 RTVPVFESVEAAVLLPEE--PVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQP 312
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKT 1190
+T L + V+T + D +L +++ +L + G+S+ V V +
Sbjct: 313 PGPGRELTHCTLAHTAGVVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDS 372
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
VV S L V+++ T V + V G + SCA+D+++ IW +
Sbjct: 373 HVVVASNSPCLKVFELQTSACQILHGHTDI-VLALDVFRKGWLFASCAKDQSVRIWRMNK 431
Query: 1251 G---LALTSFSLHVPLLGFQITSDCARVVVHLLDRG---CLPIIWLHNTPATYVKIPTYT 1304
+ + S H +G T C+R+ L G C +W P +P T
Sbjct: 432 AGQVMCVAQGSGHTHSVG---TVCCSRLKESFLVTGSQDCTVKLW----PLPKALLPKNT 484
Query: 1305 AP 1306
AP
Sbjct: 485 AP 486
Score = 61.3 bits (142), Expect = 2e-08
Identities = 36/140 (25%), Positives = 69/140 (49%), Gaps = 3/140 (2%)
Query: 943 KQMKRRQTKSTTNITLLQAEQSDLI---PISCLEVSRDGQLGASGCARGLVRVWQLSTHR 999
K + + T LLQA+ + I+ + ++ + +L A+G ++W L +
Sbjct: 477 KALLPKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQ 536
Query: 1000 LQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
L +GH + CV FSP + ++ + S D T+ +W L D S T++GH +++ + +
Sbjct: 537 LLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFV 596
Query: 1060 SDGRRAMSSDRARNVHVWLV 1079
S G + +SS V +W +
Sbjct: 597 SRGTQLLSSGSDGLVKLWTI 616
Score = 58.4 bits (135), Expect = 2e-07
Identities = 36/146 (24%), Positives = 62/146 (42%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
+AP+ + L +LW + + F GH + C+ + Q L T S D ++
Sbjct: 511 IAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIK 570
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
+W L + H A VL VA + + ++S G D V + ++ + V LD H
Sbjct: 571 LWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHED 630
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTW 805
V + + + +TG+ D V W
Sbjct: 631 KVWGLHCSRLDDHALTGASDSRVILW 656
Score = 54.0 bits (124), Expect = 4e-06
Identities = 59/254 (23%), Positives = 98/254 (38%), Gaps = 19/254 (7%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKG-HSGSILCMCVTRESQYLLTGSEDTSV 718
L+P + LV A A W S +K H+ + M S L TG D +V
Sbjct: 98 LSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGCDGAV 157
Query: 719 IVWDL--HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
VWD+ H + + ++ R L+ S D+A+ + SL D + + L
Sbjct: 158 RVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTA 217
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN------FTLLSTVTAGV-----PIHIF 825
H +VTS+ DG+ ++ +D W++++ + +V A V P+
Sbjct: 218 HYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPVSQL 277
Query: 826 DVTDDNVFLLTLQGDNELHLRTFITG----TYLHPLKRHKAKVKCFCVAHDSSRVAVGCA 881
V ++ LT L + +G T P + C +AH + V A
Sbjct: 278 GVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGRELTHC-TLAHTAGVVLTATA 336
Query: 882 DQRIYLYSLHSAQL 895
D + LY S +L
Sbjct: 337 DHNLLLYEARSLRL 350
Score = 53.6 bits (123), Expect = 5e-06
Identities = 38/165 (23%), Positives = 72/165 (43%), Gaps = 6/165 (3%)
Query: 1001 QATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMS 1060
Q T H I V +PN+ L+ +GS+DRT +W L + GH + +
Sbjct: 496 QTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSP 555
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI--DVTLNMKYAVLSDG-DNSVRIWS 1117
+ ++ + +W + L + G AS+ ++ +LS G D V++W+
Sbjct: 556 MDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWT 615
Query: 1118 LAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWK 1162
+ N+E R +H +++ + H +TG+ D + +WK
Sbjct: 616 IK---NNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILWK 657
Score = 52.8 bits (121), Expect = 9e-06
Identities = 51/215 (23%), Positives = 85/215 (39%), Gaps = 19/215 (8%)
Query: 692 GHSGSILCMCVTR-ESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVL--------C- 741
GH+ S+ +C +R + +L+TGS+D +V +W L + P+L C
Sbjct: 443 GHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLPKNTAPDNGPILLQAQTTQRCH 502
Query: 742 ------VAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFIT 795
VA N L+ +G D + +L L+ HR + V+ + T
Sbjct: 503 DKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLAT 562
Query: 796 GSQDGTVCTWNVENFTLLSTVTAGVPIHIFDV--TDDNVFLLTLQGDNELHLRTFITGTY 853
S DGT+ W +++F+ L T G + V LL+ D + L T
Sbjct: 563 ASADGTIKLWALQDFSCLKTF-EGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNEC 621
Query: 854 LHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
+ L H+ KV + G +D R+ L+
Sbjct: 622 VRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILW 656
Score = 52.4 bits (120), Expect = 1e-05
Identities = 60/289 (20%), Positives = 115/289 (39%), Gaps = 22/289 (7%)
Query: 992 VWQLSTHRLQATLNGHIGHITCVTF-SPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
+++ + RLQ G+ + V F P + V+ S + V++L ++ + + GH+
Sbjct: 342 LYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQTSACQILH-GHT 400
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVD-SGIVLHSATGPSASIDV------TLNMKY 1103
+ L + G S + ++V +W ++ +G V+ A G + V L +
Sbjct: 401 DIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESF 460
Query: 1104 AVLSDGDNSVRIWSLAGG----DNSEDNRRSV--------SHAERITCFALTADSQHVVT 1151
V D +V++W L + + DN + H + I A+ + + + T
Sbjct: 461 LVTGSQDCTVKLWPLPKALLPKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLAT 520
Query: 1152 GSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXX 1211
GS D + K+W L +L V GH + CV S ++ + + S D + +W +
Sbjct: 521 GSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQV-LATASADGTIKLWALQDFSC 579
Query: 1212 XXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
V V GT +S D + +W K + + H
Sbjct: 580 LKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAH 628
Score = 46.0 bits (104), Expect = 0.001
Identities = 28/130 (21%), Positives = 53/130 (40%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T + H I + + + L TGS+D + +W L + H + CV
Sbjct: 498 TQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMD 557
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
++ + D + + +L D + + + H SV V + G ++ DG V W ++
Sbjct: 558 QVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIK 617
Query: 809 NFTLLSTVTA 818
N + T+ A
Sbjct: 618 NNECVRTLDA 627
Score = 41.5 bits (93), Expect = 0.021
Identities = 25/107 (23%), Positives = 41/107 (38%)
Query: 971 CLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDR 1030
C++ S Q+ A+ A G +++W L T GH + V F +LS D
Sbjct: 550 CVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDG 609
Query: 1031 TVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
V +W + +N T H + L A++ V +W
Sbjct: 610 LVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILW 656
Score = 41.5 bits (93), Expect = 0.021
Identities = 27/105 (25%), Positives = 44/105 (41%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+Q +P Q L A + G +LW + S + TF+GH S+L + LL+ D
Sbjct: 551 VQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGL 610
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVII 762
V +W + + H V + ++G DS VI+
Sbjct: 611 VKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVIL 655
Score = 41.1 bits (92), Expect = 0.028
Identities = 53/260 (20%), Positives = 107/260 (41%), Gaps = 30/260 (11%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTH---RLQATLNGH---IGHITCVTFSPNNLL 1022
+ L+V R G L AS VR+W+++ A +GH +G + C +
Sbjct: 403 VLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKES--F 460
Query: 1023 VLSGSEDRTVVVWQL----------ADNSPSL-----TYKGHSSAIQTLLMMSDGRRAMS 1067
+++GS+D TV +W L DN P L T + H I ++ + + + +
Sbjct: 461 LVTGSQDCTVKLWPLPKALLPKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLAT 520
Query: 1068 SDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVL--SDGDNSVRIWSLAGGDNS 1124
+ R +W + +L +G + V + VL + D ++++W+L +
Sbjct: 521 GSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWAL---QDF 577
Query: 1125 EDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAV 1184
+ H + A + +++ D +K+W + + + L H D V +
Sbjct: 578 SCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHC 637
Query: 1185 SITNKTQVVSGSWDCNLIVW 1204
S + ++G+ D +I+W
Sbjct: 638 SRLD-DHALTGASDSRVILW 656
Score = 39.9 bits (89), Expect = 0.066
Identities = 40/178 (22%), Positives = 65/178 (36%), Gaps = 5/178 (2%)
Query: 1074 VHVWLVDSGIVLHSATGPSASIDVT---LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
V++ V SG VL S D+T L+ VL ++ + A + S
Sbjct: 71 VNILEVASGAVLRSLEQEDQE-DITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWK 129
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSIT-NK 1189
H + A S + TG D +++VW + + G +V VA +
Sbjct: 130 AIHTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTR 189
Query: 1190 TQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+ S + D + VW + VT + + DG +S DK IIW+
Sbjct: 190 LLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWD 247
Score = 36.3 bits (80), Expect = 0.81
Identities = 39/169 (23%), Positives = 67/169 (39%), Gaps = 10/169 (5%)
Query: 958 LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVW---QLSTHRLQATLNGHIGHITCV 1014
L EQ D I+ ++S D ++ + L+ W + S RL + H + +
Sbjct: 82 LRSLEQEDQEDITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAI--HTAPVATM 139
Query: 1015 TFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAM--SSDRAR 1072
F P + L+ +G D V VW + + + ++G + + D R + SS
Sbjct: 140 AFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDA 199
Query: 1073 NVHVW-LVDSGIVLHSATGPSASIDVTLNMK-YAVLSDG-DNSVRIWSL 1118
+ VW L D + SA + + + +LS G D IW L
Sbjct: 200 AIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDL 248
>CR456762-1|CAG33043.1| 655|Homo sapiens KATNB1 protein.
Length = 655
Score = 77.8 bits (183), Expect = 3e-13
Identities = 41/154 (26%), Positives = 70/154 (45%), Gaps = 3/154 (1%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
P+ + ++ +L +G G +RVW L ++ TL GH +I + F P V SGS
Sbjct: 65 PVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGS 124
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH- 1086
+D + +W + Y+GHS A++ L DG+ S+ V +W + +G ++
Sbjct: 125 QDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSE 184
Query: 1087 --SATGPSASIDVTLNMKYAVLSDGDNSVRIWSL 1118
TGP ++ N D ++R W L
Sbjct: 185 FPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDL 218
Score = 69.3 bits (162), Expect = 9e-11
Identities = 36/153 (23%), Positives = 75/153 (49%), Gaps = 1/153 (0%)
Query: 665 QHLVLAPS-AGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
+ L++A S +G ++W + + + T GH +I + +++ +GS+DT++ +WD+
Sbjct: 75 EELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDI 134
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTS 783
+ H V C+ + + S DD V + L G ++++ H G V
Sbjct: 135 RRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNV 194
Query: 784 VKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV 816
V+ + + +GS D T+ W++E F ++S +
Sbjct: 195 VEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCI 227
Score = 65.7 bits (153), Expect = 1e-09
Identities = 46/179 (25%), Positives = 77/179 (43%), Gaps = 7/179 (3%)
Query: 1083 IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVS-HAERITCFA 1141
IV H++ S + A D D V +WS+ N + S++ H +
Sbjct: 16 IVAHASNVSSLVLGKASGRLLATGGD-DCRVNLWSI----NKPNCIMSLTGHTSPVESVR 70
Query: 1142 LTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNL 1201
L + +V GS S++VW L+ K+ + L+GH + + + V SGS D N+
Sbjct: 71 LNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEF-VASGSQDTNI 129
Query: 1202 IVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
+WDI V C++ + DG S A+D T+ +W+ G ++ F H
Sbjct: 130 KLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGH 188
Score = 63.3 bits (147), Expect = 6e-09
Identities = 40/152 (26%), Positives = 68/152 (44%), Gaps = 1/152 (0%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L P G+ + + +LW I V ++GHS ++ C+ + + ++L + ++D +
Sbjct: 111 LDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHT 170
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V +WDL + ++ H PV V N L+ SG D + L +V+ ++
Sbjct: 171 VKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGE 230
Query: 778 RGSVTSVKVIQDGNIFITGSQDG-TVCTWNVE 808
G V SV DG +G QD V W E
Sbjct: 231 PGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPE 262
Score = 62.5 bits (145), Expect = 1e-08
Identities = 30/94 (31%), Positives = 46/94 (48%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ CL S DG+ AS V++W L+ ++ + GH G + V F PN L+ SGS
Sbjct: 150 VRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSS 209
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDG 1062
DRT+ W L +G ++++L DG
Sbjct: 210 DRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDG 243
Score = 55.2 bits (127), Expect = 2e-06
Identities = 44/206 (21%), Positives = 89/206 (43%), Gaps = 8/206 (3%)
Query: 1049 HSSAIQTLLM-MSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVL 1106
H+S + +L++ + GR + V++W ++ + S TG ++ ++ V LN ++
Sbjct: 19 HASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELI 78
Query: 1107 SDGDNS--VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLD 1164
G S +R+W L + ++ R + H I + V +GS D ++K+W +
Sbjct: 79 VAGSQSGSIRVWDL---EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIR 135
Query: 1165 GGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTC 1224
GHS V C+ S K + S + D + +WD+ V
Sbjct: 136 RKGCVFRYRGHSQAVRCLRFSPDGKW-LASAADDHTVKLWDLTAGKMMSEFPGHTGPVNV 194
Query: 1225 VKVTGDGTIAVSCAEDKTLIIWETKR 1250
V+ + + S + D+T+ W+ ++
Sbjct: 195 VEFHPNEYLLASGSSDRTIRFWDLEK 220
Score = 53.2 bits (122), Expect = 7e-06
Identities = 42/208 (20%), Positives = 85/208 (40%), Gaps = 6/208 (2%)
Query: 978 GQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL 1037
G+L A+G V +W ++ +L GH + V + L+++GS+ ++ VW L
Sbjct: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
Query: 1038 ADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-- 1095
T GH + I +L G S + N+ +W + + G S ++
Sbjct: 93 EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC 152
Query: 1096 -DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSM 1154
+ + K+ + D++V++W L G + H + + + +GS
Sbjct: 153 LRFSPDGKWLASAADDHTVKLWDLTAGKMMSE---FPGHTGPVNVVEFHPNEYLLASGSS 209
Query: 1155 DMSLKVWKLDGGKLSQVLVGHSDIVTCV 1182
D +++ W L+ ++ + G V V
Sbjct: 210 DRTIRFWDLEKFQVVSCIEGEPGPVRSV 237
Score = 52.4 bits (120), Expect = 1e-05
Identities = 39/213 (18%), Positives = 83/213 (38%), Gaps = 2/213 (0%)
Query: 686 KVHTFKGHSGSILCMCVTRESQYLL-TGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAA 744
K+ H+ ++ + + + S LL TG +D V +W ++ + H +PV V
Sbjct: 12 KLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRL 71
Query: 745 IVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
L+++G ++ + L ++ L H+ ++ S+ G +GSQD +
Sbjct: 72 NTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKL 131
Query: 805 WNVENFTLLSTVTA-GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAK 863
W++ + + + D +L + D+ + L G + H
Sbjct: 132 WDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGP 191
Query: 864 VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
V + +A G +D+ I + L Q++
Sbjct: 192 VNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVV 224
Score = 51.6 bits (118), Expect = 2e-05
Identities = 38/211 (18%), Positives = 82/211 (38%), Gaps = 2/211 (0%)
Query: 678 LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIA 737
LW I + + + GH+ + + + + ++ GS+ S+ VWDL + ++ H A
Sbjct: 47 LWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKA 106
Query: 738 PVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGS 797
+ + V SG D+ + + + V + H +V ++ DG + +
Sbjct: 107 NICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAA 166
Query: 798 QDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
D TV W++ ++S P+++ + + L + D + +
Sbjct: 167 DDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSC 226
Query: 857 LKRHKAKVKCFCVAHDSSRVAVGCADQ-RIY 886
++ V+ D + GC D R+Y
Sbjct: 227 IEGEPGPVRSVLFNPDGCCLYSGCQDSLRVY 257
Score = 44.8 bits (101), Expect = 0.002
Identities = 28/103 (27%), Positives = 44/103 (42%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R L+ +P G+ L A +LW + + + F GH+G + + L +GS D
Sbjct: 151 RCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSD 210
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDS 758
++ WDL V + I PV V + + SG DS
Sbjct: 211 RTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDS 253
Score = 37.1 bits (82), Expect = 0.46
Identities = 17/62 (27%), Positives = 32/62 (51%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
P++ +E + L ASG + +R W L ++ + + G G + V F+P+ + SG
Sbjct: 191 PVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGC 250
Query: 1028 ED 1029
+D
Sbjct: 251 QD 252
>BT007022-1|AAP35668.1| 655|Homo sapiens katanin p80
(WD40-containing) subunit B 1 protein.
Length = 655
Score = 77.8 bits (183), Expect = 3e-13
Identities = 41/154 (26%), Positives = 70/154 (45%), Gaps = 3/154 (1%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
P+ + ++ +L +G G +RVW L ++ TL GH +I + F P V SGS
Sbjct: 65 PVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGS 124
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH- 1086
+D + +W + Y+GHS A++ L DG+ S+ V +W + +G ++
Sbjct: 125 QDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSE 184
Query: 1087 --SATGPSASIDVTLNMKYAVLSDGDNSVRIWSL 1118
TGP ++ N D ++R W L
Sbjct: 185 FPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDL 218
Score = 69.3 bits (162), Expect = 9e-11
Identities = 36/153 (23%), Positives = 75/153 (49%), Gaps = 1/153 (0%)
Query: 665 QHLVLAPS-AGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
+ L++A S +G ++W + + + T GH +I + +++ +GS+DT++ +WD+
Sbjct: 75 EELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDI 134
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTS 783
+ H V C+ + + S DD V + L G ++++ H G V
Sbjct: 135 RRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNV 194
Query: 784 VKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV 816
V+ + + +GS D T+ W++E F ++S +
Sbjct: 195 VEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCI 227
Score = 65.7 bits (153), Expect = 1e-09
Identities = 46/179 (25%), Positives = 77/179 (43%), Gaps = 7/179 (3%)
Query: 1083 IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVS-HAERITCFA 1141
IV H++ S + A D D V +WS+ N + S++ H +
Sbjct: 16 IVAHASNVSSLVLGKASGRLLATGGD-DCRVNLWSI----NKPNCIMSLTGHTSPVESVR 70
Query: 1142 LTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNL 1201
L + +V GS S++VW L+ K+ + L+GH + + + V SGS D N+
Sbjct: 71 LNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEF-VASGSQDTNI 129
Query: 1202 IVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
+WDI V C++ + DG S A+D T+ +W+ G ++ F H
Sbjct: 130 KLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGH 188
Score = 63.3 bits (147), Expect = 6e-09
Identities = 40/152 (26%), Positives = 68/152 (44%), Gaps = 1/152 (0%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L P G+ + + +LW I V ++GHS ++ C+ + + ++L + ++D +
Sbjct: 111 LDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHT 170
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V +WDL + ++ H PV V N L+ SG D + L +V+ ++
Sbjct: 171 VKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGE 230
Query: 778 RGSVTSVKVIQDGNIFITGSQDG-TVCTWNVE 808
G V SV DG +G QD V W E
Sbjct: 231 PGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPE 262
Score = 62.5 bits (145), Expect = 1e-08
Identities = 30/94 (31%), Positives = 46/94 (48%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ CL S DG+ AS V++W L+ ++ + GH G + V F PN L+ SGS
Sbjct: 150 VRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSS 209
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDG 1062
DRT+ W L +G ++++L DG
Sbjct: 210 DRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDG 243
Score = 55.2 bits (127), Expect = 2e-06
Identities = 44/206 (21%), Positives = 89/206 (43%), Gaps = 8/206 (3%)
Query: 1049 HSSAIQTLLM-MSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVL 1106
H+S + +L++ + GR + V++W ++ + S TG ++ ++ V LN ++
Sbjct: 19 HASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELI 78
Query: 1107 SDGDNS--VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLD 1164
G S +R+W L + ++ R + H I + V +GS D ++K+W +
Sbjct: 79 VAGSQSGSIRVWDL---EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIR 135
Query: 1165 GGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTC 1224
GHS V C+ S K + S + D + +WD+ V
Sbjct: 136 RKGCVFRYRGHSQAVRCLRFSPDGKW-LASAADDHTVKLWDLTAGKMMSEFPGHTGPVNV 194
Query: 1225 VKVTGDGTIAVSCAEDKTLIIWETKR 1250
V+ + + S + D+T+ W+ ++
Sbjct: 195 VEFHPNEYLLASGSSDRTIRFWDLEK 220
Score = 53.2 bits (122), Expect = 7e-06
Identities = 42/208 (20%), Positives = 85/208 (40%), Gaps = 6/208 (2%)
Query: 978 GQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL 1037
G+L A+G V +W ++ +L GH + V + L+++GS+ ++ VW L
Sbjct: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
Query: 1038 ADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-- 1095
T GH + I +L G S + N+ +W + + G S ++
Sbjct: 93 EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC 152
Query: 1096 -DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSM 1154
+ + K+ + D++V++W L G + H + + + +GS
Sbjct: 153 LRFSPDGKWLASAADDHTVKLWDLTAGKMMSE---FPGHTGPVNVVEFHPNEYLLASGSS 209
Query: 1155 DMSLKVWKLDGGKLSQVLVGHSDIVTCV 1182
D +++ W L+ ++ + G V V
Sbjct: 210 DRTIRFWDLEKFQVVSCIEGEPGPVRSV 237
Score = 52.4 bits (120), Expect = 1e-05
Identities = 39/213 (18%), Positives = 83/213 (38%), Gaps = 2/213 (0%)
Query: 686 KVHTFKGHSGSILCMCVTRESQYLL-TGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAA 744
K+ H+ ++ + + + S LL TG +D V +W ++ + H +PV V
Sbjct: 12 KLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRL 71
Query: 745 IVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
L+++G ++ + L ++ L H+ ++ S+ G +GSQD +
Sbjct: 72 NTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKL 131
Query: 805 WNVENFTLLSTVTA-GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAK 863
W++ + + + D +L + D+ + L G + H
Sbjct: 132 WDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGP 191
Query: 864 VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
V + +A G +D+ I + L Q++
Sbjct: 192 VNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVV 224
Score = 51.6 bits (118), Expect = 2e-05
Identities = 38/211 (18%), Positives = 82/211 (38%), Gaps = 2/211 (0%)
Query: 678 LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIA 737
LW I + + + GH+ + + + + ++ GS+ S+ VWDL + ++ H A
Sbjct: 47 LWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKA 106
Query: 738 PVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGS 797
+ + V SG D+ + + + V + H +V ++ DG + +
Sbjct: 107 NICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAA 166
Query: 798 QDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
D TV W++ ++S P+++ + + L + D + +
Sbjct: 167 DDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSC 226
Query: 857 LKRHKAKVKCFCVAHDSSRVAVGCADQ-RIY 886
++ V+ D + GC D R+Y
Sbjct: 227 IEGEPGPVRSVLFNPDGCCLYSGCQDSLRVY 257
Score = 44.8 bits (101), Expect = 0.002
Identities = 28/103 (27%), Positives = 44/103 (42%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R L+ +P G+ L A +LW + + + F GH+G + + L +GS D
Sbjct: 151 RCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSD 210
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDS 758
++ WDL V + I PV V + + SG DS
Sbjct: 211 RTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDS 253
Score = 37.1 bits (82), Expect = 0.46
Identities = 17/62 (27%), Positives = 32/62 (51%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
P++ +E + L ASG + +R W L ++ + + G G + V F+P+ + SG
Sbjct: 191 PVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGC 250
Query: 1028 ED 1029
+D
Sbjct: 251 QD 252
>BC001353-1|AAH01353.1| 655|Homo sapiens katanin p80 (WD repeat
containing) subunit B 1 protein.
Length = 655
Score = 77.8 bits (183), Expect = 3e-13
Identities = 41/154 (26%), Positives = 70/154 (45%), Gaps = 3/154 (1%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
P+ + ++ +L +G G +RVW L ++ TL GH +I + F P V SGS
Sbjct: 65 PVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGS 124
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH- 1086
+D + +W + Y+GHS A++ L DG+ S+ V +W + +G ++
Sbjct: 125 QDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSE 184
Query: 1087 --SATGPSASIDVTLNMKYAVLSDGDNSVRIWSL 1118
TGP ++ N D ++R W L
Sbjct: 185 FPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDL 218
Score = 69.3 bits (162), Expect = 9e-11
Identities = 36/153 (23%), Positives = 75/153 (49%), Gaps = 1/153 (0%)
Query: 665 QHLVLAPS-AGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
+ L++A S +G ++W + + + T GH +I + +++ +GS+DT++ +WD+
Sbjct: 75 EELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDI 134
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTS 783
+ H V C+ + + S DD V + L G ++++ H G V
Sbjct: 135 RRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNV 194
Query: 784 VKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV 816
V+ + + +GS D T+ W++E F ++S +
Sbjct: 195 VEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCI 227
Score = 65.7 bits (153), Expect = 1e-09
Identities = 46/179 (25%), Positives = 77/179 (43%), Gaps = 7/179 (3%)
Query: 1083 IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVS-HAERITCFA 1141
IV H++ S + A D D V +WS+ N + S++ H +
Sbjct: 16 IVAHASNVSSLVLGKASGRLLATGGD-DCRVNLWSI----NKPNCIMSLTGHTSPVESVR 70
Query: 1142 LTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNL 1201
L + +V GS S++VW L+ K+ + L+GH + + + V SGS D N+
Sbjct: 71 LNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEF-VASGSQDTNI 129
Query: 1202 IVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
+WDI V C++ + DG S A+D T+ +W+ G ++ F H
Sbjct: 130 KLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGH 188
Score = 63.3 bits (147), Expect = 6e-09
Identities = 40/152 (26%), Positives = 68/152 (44%), Gaps = 1/152 (0%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L P G+ + + +LW I V ++GHS ++ C+ + + ++L + ++D +
Sbjct: 111 LDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHT 170
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V +WDL + ++ H PV V N L+ SG D + L +V+ ++
Sbjct: 171 VKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGE 230
Query: 778 RGSVTSVKVIQDGNIFITGSQDG-TVCTWNVE 808
G V SV DG +G QD V W E
Sbjct: 231 PGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPE 262
Score = 62.5 bits (145), Expect = 1e-08
Identities = 30/94 (31%), Positives = 46/94 (48%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ CL S DG+ AS V++W L+ ++ + GH G + V F PN L+ SGS
Sbjct: 150 VRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSS 209
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDG 1062
DRT+ W L +G ++++L DG
Sbjct: 210 DRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDG 243
Score = 55.2 bits (127), Expect = 2e-06
Identities = 44/206 (21%), Positives = 89/206 (43%), Gaps = 8/206 (3%)
Query: 1049 HSSAIQTLLM-MSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVL 1106
H+S + +L++ + GR + V++W ++ + S TG ++ ++ V LN ++
Sbjct: 19 HASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELI 78
Query: 1107 SDGDNS--VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLD 1164
G S +R+W L + ++ R + H I + V +GS D ++K+W +
Sbjct: 79 VAGSQSGSIRVWDL---EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIR 135
Query: 1165 GGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTC 1224
GHS V C+ S K + S + D + +WD+ V
Sbjct: 136 RKGCVFRYRGHSQAVRCLRFSPDGKW-LASAADDHTVKLWDLTAGKMMSEFPGHTGPVNV 194
Query: 1225 VKVTGDGTIAVSCAEDKTLIIWETKR 1250
V+ + + S + D+T+ W+ ++
Sbjct: 195 VEFHPNEYLLASGSSDRTIRFWDLEK 220
Score = 53.2 bits (122), Expect = 7e-06
Identities = 42/208 (20%), Positives = 85/208 (40%), Gaps = 6/208 (2%)
Query: 978 GQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL 1037
G+L A+G V +W ++ +L GH + V + L+++GS+ ++ VW L
Sbjct: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
Query: 1038 ADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-- 1095
T GH + I +L G S + N+ +W + + G S ++
Sbjct: 93 EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC 152
Query: 1096 -DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSM 1154
+ + K+ + D++V++W L G + H + + + +GS
Sbjct: 153 LRFSPDGKWLASAADDHTVKLWDLTAGKMMSE---FPGHTGPVNVVEFHPNEYLLASGSS 209
Query: 1155 DMSLKVWKLDGGKLSQVLVGHSDIVTCV 1182
D +++ W L+ ++ + G V V
Sbjct: 210 DRTIRFWDLEKFQVVSCIEGEPGPVRSV 237
Score = 52.4 bits (120), Expect = 1e-05
Identities = 39/213 (18%), Positives = 83/213 (38%), Gaps = 2/213 (0%)
Query: 686 KVHTFKGHSGSILCMCVTRESQYLL-TGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAA 744
K+ H+ ++ + + + S LL TG +D V +W ++ + H +PV V
Sbjct: 12 KLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRL 71
Query: 745 IVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
L+++G ++ + L ++ L H+ ++ S+ G +GSQD +
Sbjct: 72 NTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKL 131
Query: 805 WNVENFTLLSTVTA-GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAK 863
W++ + + + D +L + D+ + L G + H
Sbjct: 132 WDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGP 191
Query: 864 VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
V + +A G +D+ I + L Q++
Sbjct: 192 VNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVV 224
Score = 51.6 bits (118), Expect = 2e-05
Identities = 38/211 (18%), Positives = 82/211 (38%), Gaps = 2/211 (0%)
Query: 678 LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIA 737
LW I + + + GH+ + + + + ++ GS+ S+ VWDL + ++ H A
Sbjct: 47 LWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKA 106
Query: 738 PVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGS 797
+ + V SG D+ + + + V + H +V ++ DG + +
Sbjct: 107 NICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAA 166
Query: 798 QDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
D TV W++ ++S P+++ + + L + D + +
Sbjct: 167 DDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSC 226
Query: 857 LKRHKAKVKCFCVAHDSSRVAVGCADQ-RIY 886
++ V+ D + GC D R+Y
Sbjct: 227 IEGEPGPVRSVLFNPDGCCLYSGCQDSLRVY 257
Score = 44.8 bits (101), Expect = 0.002
Identities = 28/103 (27%), Positives = 44/103 (42%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R L+ +P G+ L A +LW + + + F GH+G + + L +GS D
Sbjct: 151 RCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSD 210
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDS 758
++ WDL V + I PV V + + SG DS
Sbjct: 211 RTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDS 253
Score = 37.1 bits (82), Expect = 0.46
Identities = 17/62 (27%), Positives = 32/62 (51%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
P++ +E + L ASG + +R W L ++ + + G G + V F+P+ + SG
Sbjct: 191 PVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGC 250
Query: 1028 ED 1029
+D
Sbjct: 251 QD 252
>X04526-2|CAA28207.1| 340|Homo sapiens protein ( Human liver mRNA for
beta-subunit signal transducing proteins Gs/Gi (beta-G).
).
Length = 340
Score = 77.4 bits (182), Expect = 4e-13
Identities = 60/239 (25%), Positives = 106/239 (44%), Gaps = 18/239 (7%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N +V S S D T
Sbjct: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + + T+ GH+ + +L + D R +S + +W V G+ + TG +
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227
Query: 1094 SIDVTL----NMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE---RITCFALTADS 1146
I+ +A SD D + R++ L ++ + SH IT + +
Sbjct: 228 DINAICFFPNGNAFATGSD-DATCRLFDL----RADQELMTYSHDNIICGITSVSFSKSG 282
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ ++ G D + VW + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 283 RLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 340
Score = 68.1 bits (159), Expect = 2e-10
Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + T GH G + ++ +P+ L +SG+
Sbjct: 146 LSCCRFLDDNQIVTSS-GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRR-AMSSDRAR-NVHVWLVDSGIVLH 1086
D + +W + + T+ GH S I + +G A SD A + D ++ +
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V+ + +L G D + +W D + H R++C +T
Sbjct: 265 SHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 322 DDGMAVATGSWDSFLKIW 339
Score = 63.3 bits (147), Expect = 6e-09
Identities = 46/201 (22%), Positives = 84/201 (41%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T T H V+ ++ + L
Sbjct: 141 GHTGYLSC-CRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT 811
+SG D++ + + +G H + ++ +GN F TGS D T +++
Sbjct: 200 VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 259
Query: 812 LLSTVT-AGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
L T + + I V+ L L G ++ + + + L H +V C
Sbjct: 260 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLKIWN 340
Score = 57.6 bits (133), Expect = 3e-07
Identities = 43/183 (23%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Query: 669 LAPSAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+ S+GD LW I + + TF GH+G ++ + + +++ ++G+ D S +WD+
Sbjct: 157 IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSV 784
+ H + + + N + +G DD+ + L D L+T D+ +TSV
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSV 276
Query: 785 KVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNE 842
+ G + + G D W+ + V AG + VTDD + + T D+
Sbjct: 277 SFSKSGRLLLAGYDDFNCNVWDALKAD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSF 335
Query: 843 LHL 845
L +
Sbjct: 336 LKI 338
Score = 56.0 bits (129), Expect = 9e-07
Identities = 50/257 (19%), Positives = 96/257 (37%), Gaps = 12/257 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSA--TGPSASIDVT--LNMKYAVLSDGDNS 1112
G D +++ G V S G + + L+ V S GD +
Sbjct: 106 APSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + G + H + +L D++ V+G+ D S K+W + G Q
Sbjct: 166 CALWDIETG---QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
GH + + N +GS D ++D+ +T V +
Sbjct: 223 TGHESDINAICF-FPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKS 281
Query: 1231 GTIAVSCAEDKTLIIWE 1247
G + ++ +D +W+
Sbjct: 282 GRLLLAGYDDFNCNVWD 298
Score = 54.8 bits (126), Expect = 2e-06
Identities = 50/215 (23%), Positives = 87/215 (40%), Gaps = 6/215 (2%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D I +T S D T
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAK 863
W++E +T T + + D ++ D L G H++
Sbjct: 169 WDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESD 228
Query: 864 VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ C + + A G D L+ L + Q L T
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMT 263
Score = 53.2 bits (122), Expect = 7e-06
Identities = 35/155 (22%), Positives = 62/155 (40%), Gaps = 5/155 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +KVH S ++ Y+ G D +++L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + +V S GD + + + G T H G V
Sbjct: 130 EGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA-LWDIETGQQTTTFTGHTGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
S+ + D +F++G+ D + W+V T T
Sbjct: 189 SLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFT 223
Score = 51.2 bits (117), Expect = 3e-05
Identities = 43/219 (19%), Positives = 95/219 (43%), Gaps = 8/219 (3%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
Y DN I++L + N +R H ++C D+Q +VT S D + +
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXXXXXXXX 1219
W ++ G+ + GH+ V +++S+ T++ VSG+ D + +WD+
Sbjct: 169 WDIETGQQTTTFTGHTGDV--MSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 1220 XKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D T +++ + L ++S
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS 265
Score = 50.4 bits (115), Expect = 5e-05
Identities = 58/291 (19%), Positives = 111/291 (38%), Gaps = 16/291 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNYVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDT-TCALWDIE 172
Query: 1081 SG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+G TG S+ + + + V D S ++W + G + H I
Sbjct: 173 TGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG---MCRQTFTGHESDI 229
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKTQVV-SG 1195
+ TGS D + +++ L + + H +I+ + +VS + +++ +G
Sbjct: 230 NAICFFPNGNAFATGSDDATCRLFDLRADQ-ELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
D N VWD +V+C+ VT DG + + D L IW
Sbjct: 289 YDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 49.6 bits (113), Expect = 8e-05
Identities = 38/151 (25%), Positives = 60/151 (39%), Gaps = 2/151 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP + V +LW + TF GH I +C TGS+D +
Sbjct: 190 LSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDAT 249
Query: 718 VIVWDLHT-LAVKTKILEH-IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
++DL + T ++ I + V+ + L+++G DD + + L
Sbjct: 250 CRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLA 309
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 310 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 49.2 bits (112), Expect = 1e-04
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A +V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 101 MTC-AYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN--QI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
V+ S D +WDI T V + + D + VS A D + +W+ + G+
Sbjct: 158 VTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGM 217
Query: 1253 ALTSFSLH 1260
+F+ H
Sbjct: 218 CRQTFTGH 225
>M36430-1|AAA63265.1| 247|Homo sapiens protein ( Human transducin
beta-1 subunit mRNA, 3' end. ).
Length = 247
Score = 77.4 bits (182), Expect = 4e-13
Identities = 58/238 (24%), Positives = 103/238 (43%), Gaps = 16/238 (6%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N +V S S D T
Sbjct: 16 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS-SGDTTCA 74
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + + T+ GH+ + +L + D R +S + +W V G+ + TG +
Sbjct: 75 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 134
Query: 1094 SIDVTL---NMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE---RITCFALTADSQ 1147
I+ N D + R++ L ++ + SH IT + + +
Sbjct: 135 DINAICFFPNGNAFATGSDDATCRLFDL----RADQELMTYSHDNIICGITSVSFSKSGR 190
Query: 1148 HVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
++ G D + VW + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 191 LLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 247
Score = 68.1 bits (159), Expect = 2e-10
Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + T GH G + ++ +P+ L +SG+
Sbjct: 53 LSCCRFLDDNQIVTSS-GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 111
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRR-AMSSDRAR-NVHVWLVDSGIVLH 1086
D + +W + + T+ GH S I + +G A SD A + D ++ +
Sbjct: 112 DASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY 171
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V+ + +L G D + +W D + H R++C +T
Sbjct: 172 SHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRA---GVLAGHDNRVSCLGVT 228
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 229 DDGMAVATGSWDSFLKIW 246
Score = 63.3 bits (147), Expect = 6e-09
Identities = 46/201 (22%), Positives = 84/201 (41%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T T H V+ ++ + L
Sbjct: 48 GHTGYLSC-CRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLF 106
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT 811
+SG D++ + + +G H + ++ +GN F TGS D T +++
Sbjct: 107 VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 166
Query: 812 LLSTVT-AGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
L T + + I V+ L L G ++ + + + L H +V C
Sbjct: 167 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLG 226
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 227 VTDDGMAVATGSWDSFLKIWN 247
Score = 57.6 bits (133), Expect = 3e-07
Identities = 43/183 (23%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Query: 669 LAPSAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+ S+GD LW I + + TF GH+G ++ + + +++ ++G+ D S +WD+
Sbjct: 64 IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 123
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSV 784
+ H + + + N + +G DD+ + L D L+T D+ +TSV
Sbjct: 124 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSV 183
Query: 785 KVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNE 842
+ G + + G D W+ + V AG + VTDD + + T D+
Sbjct: 184 SFSKSGRLLLAGYDDFNCNVWDALKAD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSF 242
Query: 843 LHL 845
L +
Sbjct: 243 LKI 245
Score = 49.6 bits (113), Expect = 8e-05
Identities = 38/151 (25%), Positives = 60/151 (39%), Gaps = 2/151 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP + V +LW + TF GH I +C TGS+D +
Sbjct: 97 LSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDAT 156
Query: 718 VIVWDLHT-LAVKTKILEH-IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
++DL + T ++ I + V+ + L+++G DD + + L
Sbjct: 157 CRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLA 216
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 217 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 247
Score = 49.2 bits (112), Expect = 1e-04
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A +V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 8 MTC-AYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN--QI 64
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
V+ S D +WDI T V + + D + VS A D + +W+ + G+
Sbjct: 65 VTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGM 124
Query: 1253 ALTSFSLH 1260
+F+ H
Sbjct: 125 CRQTFTGH 132
Score = 47.2 bits (107), Expect = 4e-04
Identities = 33/158 (20%), Positives = 70/158 (44%), Gaps = 5/158 (3%)
Query: 1103 YAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
Y DN I++L + N +R H ++C D+Q +VT S D + +W
Sbjct: 18 YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALW 76
Query: 1162 KLDGGKLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
++ G+ + GH+ V +++S+ T++ VSG+ D + +WD+
Sbjct: 77 DIETGQQTTTFTGHTGDV--MSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 134
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D T +++ + L ++S
Sbjct: 135 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS 172
Score = 46.4 bits (105), Expect = 8e-04
Identities = 49/245 (20%), Positives = 94/245 (38%), Gaps = 15/245 (6%)
Query: 1011 ITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAM 1066
+TC ++P+ V G D ++ L ++ GH+ + + D +
Sbjct: 8 MTCA-YAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVT 66
Query: 1067 SSDRARNVHVWLVDSG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDN 1123
SS +W +++G TG S+ + + + V D S ++W + G
Sbjct: 67 SSGDT-TCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG-- 123
Query: 1124 SEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV- 1182
+ H I + TGS D + +++ L + + H +I+ +
Sbjct: 124 -MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ-ELMTYSHDNIICGIT 181
Query: 1183 AVSITNKTQVV-SGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDK 1241
+VS + +++ +G D N VWD +V+C+ VT DG + + D
Sbjct: 182 SVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDS 241
Query: 1242 TLIIW 1246
L IW
Sbjct: 242 FLKIW 246
Score = 44.8 bits (101), Expect = 0.002
Identities = 29/145 (20%), Positives = 55/145 (37%), Gaps = 6/145 (4%)
Query: 1105 VLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLD 1164
V S GD + +W + G + H + +L D++ V+G+ D S K+W +
Sbjct: 65 VTSSGDTTCALWDIETG---QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVR 121
Query: 1165 GGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KV 1222
G Q GH + + N +GS D ++D+ +
Sbjct: 122 EGMCRQTFTGHESDINAICF-FPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGI 180
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWE 1247
T V + G + ++ +D +W+
Sbjct: 181 TSVSFSKSGRLLLAGYDDFNCNVWD 205
>L13387-1|AAA02882.1| 288|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 288
Score = 77.4 bits (182), Expect = 4e-13
Identities = 62/283 (21%), Positives = 116/283 (40%), Gaps = 27/283 (9%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
++VW T + TL GH + ++F + L+ S S D T+ +W T GH
Sbjct: 10 IKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGH 69
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLS- 1107
+ ++ +M +G +S+ R + + +W V +G + + TG + V N +++
Sbjct: 70 DHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 129
Query: 1108 -DGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQH------------------ 1148
D +VR+W +A + + R H + C + +S +
Sbjct: 130 CSNDQTVRVWVVATKECKAELR---EHEHVVECISWAPESSYSSISEATGSETKKSGKPG 186
Query: 1149 --VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+++GS D ++K+W + G VGH + V V K ++S + D L VWD
Sbjct: 187 PFLLSGSRDKTIKMWDVSTGMCLMTXVGHDNWVRGVLFHSGGKF-ILSCADDKTLRVWDY 245
Query: 1207 NTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
VT + V+ + D+T+ +WE +
Sbjct: 246 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 288
Score = 68.5 bits (160), Expect = 2e-10
Identities = 57/260 (21%), Positives = 105/260 (40%), Gaps = 25/260 (9%)
Query: 1023 VLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSG 1082
++S SED T+ VW T KGH+ ++Q + G+ S + +W
Sbjct: 1 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 60
Query: 1083 IVLHSATGPS---ASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITC 1139
+ + G +S+ + N + V + D ++++W + G + H E +
Sbjct: 61 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTG---YCVKTFTGHREWVRM 117
Query: 1140 FALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVA-------VSITNKTQ- 1191
D + + S D +++VW + + L H +V C++ SI+ T
Sbjct: 118 VRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGS 177
Query: 1192 -----------VVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAED 1240
++SGS D + +WD++T V V G +SCA+D
Sbjct: 178 ETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTXVGHDNWVRGVLFHSGGKFILSCADD 237
Query: 1241 KTLIIWETKRGLALTSFSLH 1260
KTL +W+ K + + + H
Sbjct: 238 KTLRVWDYKNKRCMKTLNAH 257
Score = 52.4 bits (120), Expect = 1e-05
Identities = 35/141 (24%), Positives = 57/141 (40%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+V A ++W + T KGH+ S+ + + L + S D ++ +WD
Sbjct: 1 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 60
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
+ H V VA + N ++S D + + + G V HR V V+
Sbjct: 61 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRP 120
Query: 787 IQDGNIFITGSQDGTVCTWNV 807
QDG + + S D TV W V
Sbjct: 121 NQDGTLIASCSNDQTVRVWVV 141
Score = 50.4 bits (115), Expect = 5e-05
Identities = 34/167 (20%), Positives = 71/167 (42%), Gaps = 1/167 (0%)
Query: 709 LLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDG 768
+++ SED ++ VWD T + + H V ++ + L+ S D + +
Sbjct: 1 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 60
Query: 769 ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP-IHIFDV 827
+ + H +V+SV ++ +G+ ++ S+D T+ W V+ + T T + +
Sbjct: 61 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRP 120
Query: 828 TDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSS 874
D + + D + + T L+ H+ V+C A +SS
Sbjct: 121 NQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESS 167
Score = 44.8 bits (101), Expect = 0.002
Identities = 37/179 (20%), Positives = 70/179 (39%), Gaps = 20/179 (11%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
+ P+G H+V A ++W + + V TF GH + + ++ + + S D +V
Sbjct: 78 IMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVR 137
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRS--------------------LVISGGDDSA 759
VW + T K ++ EH V C++ S ++SG D
Sbjct: 138 VWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKT 197
Query: 760 VIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA 818
+ + + G + H V V G ++ + D T+ W+ +N + T+ A
Sbjct: 198 IKMWDVSTGMCLMTXVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA 256
Score = 43.6 bits (98), Expect = 0.005
Identities = 51/290 (17%), Positives = 104/290 (35%), Gaps = 12/290 (4%)
Query: 794 ITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNV--FLLTLQGDNELHLRTFITG 851
++ S+D T+ W+ E T+ G + D++ D+ L + D + L F
Sbjct: 2 VSASEDATIKVWDYETGDFERTLK-GHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 60
Query: 852 TYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXXXX 911
+ + H V + + + D+ I ++ + + ++T
Sbjct: 61 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRP 120
Query: 912 XXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLL-QAEQSDLIPIS 970
L+A+ N T+ + + + K R I+ ++ S + +
Sbjct: 121 NQDGTLIASCSNDQTVRVW-----VVATKECKAELREHEHVVECISWAPESSYSSISEAT 175
Query: 971 CLEVSRDGQLGA---SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
E + G+ G SG +++W +ST T GH + V F +LS +
Sbjct: 176 GSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTXVGHDNWVRGVLFHSGGKFILSCA 235
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
+D+T+ VW + T H + +L ++ + V VW
Sbjct: 236 DDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 285
Score = 40.3 bits (90), Expect = 0.050
Identities = 26/98 (26%), Positives = 43/98 (43%)
Query: 708 YLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVD 767
+LL+GS D ++ +WD+ T + H V V ++S DD + + +
Sbjct: 188 FLLSGSRDKTIKMWDVSTGMCLMTXVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 247
Query: 768 GALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
+ L+ H VTS+ + +TGS D TV W
Sbjct: 248 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 285
Score = 33.9 bits (74), Expect = 4.3
Identities = 47/248 (18%), Positives = 92/248 (37%), Gaps = 23/248 (9%)
Query: 663 SGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWD 722
SG+ L + +LW + T GH ++ + + ++++ S D ++ +W+
Sbjct: 39 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 98
Query: 723 LHT-LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH---- 777
+ T VKT H V V + +L+ S +D V + + +L H
Sbjct: 99 VQTGYCVKT-FTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVV 157
Query: 778 -------RGSVTSV---------KVIQDGNIFITGSQDGTVCTWNVE-NFTLLSTVTAGV 820
S +S+ K + G ++GS+D T+ W+V L++ V
Sbjct: 158 ECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTXVGHDN 217
Query: 821 PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGC 880
+ F+L+ D L + + + L H+ V + V G
Sbjct: 218 WVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGS 277
Query: 881 ADQRIYLY 888
DQ + ++
Sbjct: 278 VDQTVKVW 285
>CR456784-1|CAG33065.1| 340|Homo sapiens GNB1 protein.
Length = 340
Score = 77.4 bits (182), Expect = 4e-13
Identities = 60/239 (25%), Positives = 106/239 (44%), Gaps = 18/239 (7%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N +V S S D T
Sbjct: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + + T+ GH+ + +L + D R +S + +W V G+ + TG +
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227
Query: 1094 SIDVTL----NMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE---RITCFALTADS 1146
I+ +A SD D + R++ L ++ + SH IT + +
Sbjct: 228 DINAICFFPNGNAFATGSD-DATCRLFDL----RADQELMTYSHDNIICGITSVSFSKSG 282
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ ++ G D + VW + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 283 RLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 340
Score = 68.1 bits (159), Expect = 2e-10
Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + T GH G + ++ +P+ L +SG+
Sbjct: 146 LSCCRFLDDNQIVTSS-GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRR-AMSSDRAR-NVHVWLVDSGIVLH 1086
D + +W + + T+ GH S I + +G A SD A + D ++ +
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V+ + +L G D + +W D + H R++C +T
Sbjct: 265 SHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 322 DDGMAVATGSWDSFLKIW 339
Score = 63.3 bits (147), Expect = 6e-09
Identities = 46/201 (22%), Positives = 84/201 (41%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T T H V+ ++ + L
Sbjct: 141 GHTGYLSC-CRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT 811
+SG D++ + + +G H + ++ +GN F TGS D T +++
Sbjct: 200 VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 259
Query: 812 LLSTVT-AGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
L T + + I V+ L L G ++ + + + L H +V C
Sbjct: 260 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLKIWN 340
Score = 57.6 bits (133), Expect = 3e-07
Identities = 43/183 (23%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Query: 669 LAPSAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+ S+GD LW I + + TF GH+G ++ + + +++ ++G+ D S +WD+
Sbjct: 157 IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSV 784
+ H + + + N + +G DD+ + L D L+T D+ +TSV
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSV 276
Query: 785 KVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNE 842
+ G + + G D W+ + V AG + VTDD + + T D+
Sbjct: 277 SFSKSGRLLLAGYDDFNCNVWDALKAD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSF 335
Query: 843 LHL 845
L +
Sbjct: 336 LKI 338
Score = 56.0 bits (129), Expect = 9e-07
Identities = 50/257 (19%), Positives = 96/257 (37%), Gaps = 12/257 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSA--TGPSASIDVT--LNMKYAVLSDGDNS 1112
G D +++ G V S G + + L+ V S GD +
Sbjct: 106 APSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + G + H + +L D++ V+G+ D S K+W + G Q
Sbjct: 166 CALWDIETG---QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
GH + + N +GS D ++D+ +T V +
Sbjct: 223 TGHESDINAICF-FPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKS 281
Query: 1231 GTIAVSCAEDKTLIIWE 1247
G + ++ +D +W+
Sbjct: 282 GRLLLAGYDDFNCNVWD 298
Score = 54.8 bits (126), Expect = 2e-06
Identities = 50/215 (23%), Positives = 87/215 (40%), Gaps = 6/215 (2%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D I +T S D T
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAK 863
W++E +T T + + D ++ D L G H++
Sbjct: 169 WDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESD 228
Query: 864 VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ C + + A G D L+ L + Q L T
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMT 263
Score = 53.2 bits (122), Expect = 7e-06
Identities = 35/155 (22%), Positives = 62/155 (40%), Gaps = 5/155 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +KVH S ++ Y+ G D +++L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + +V S GD + + + G T H G V
Sbjct: 130 EGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA-LWDIETGQQTTTFTGHTGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
S+ + D +F++G+ D + W+V T T
Sbjct: 189 SLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFT 223
Score = 51.2 bits (117), Expect = 3e-05
Identities = 43/219 (19%), Positives = 95/219 (43%), Gaps = 8/219 (3%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
Y DN I++L + N +R H ++C D+Q +VT S D + +
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXXXXXXXX 1219
W ++ G+ + GH+ V +++S+ T++ VSG+ D + +WD+
Sbjct: 169 WDIETGQQTTTFTGHTGDV--MSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 1220 XKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D T +++ + L ++S
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS 265
Score = 50.4 bits (115), Expect = 5e-05
Identities = 58/291 (19%), Positives = 111/291 (38%), Gaps = 16/291 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNYVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDT-TCALWDIE 172
Query: 1081 SG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+G TG S+ + + + V D S ++W + G + H I
Sbjct: 173 TGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG---MCRQTFTGHESDI 229
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKTQVV-SG 1195
+ TGS D + +++ L + + H +I+ + +VS + +++ +G
Sbjct: 230 NAICFFPNGNAFATGSDDATCRLFDLRADQ-ELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
D N VWD +V+C+ VT DG + + D L IW
Sbjct: 289 YDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 49.6 bits (113), Expect = 8e-05
Identities = 38/151 (25%), Positives = 60/151 (39%), Gaps = 2/151 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP + V +LW + TF GH I +C TGS+D +
Sbjct: 190 LSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDAT 249
Query: 718 VIVWDLHT-LAVKTKILEH-IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
++DL + T ++ I + V+ + L+++G DD + + L
Sbjct: 250 CRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLA 309
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 310 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 49.2 bits (112), Expect = 1e-04
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A +V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 101 MTC-AYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN--QI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
V+ S D +WDI T V + + D + VS A D + +W+ + G+
Sbjct: 158 VTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGM 217
Query: 1253 ALTSFSLH 1260
+F+ H
Sbjct: 218 CRQTFTGH 225
>BT007305-1|AAP35969.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 77.4 bits (182), Expect = 4e-13
Identities = 60/239 (25%), Positives = 106/239 (44%), Gaps = 18/239 (7%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N +V S S D T
Sbjct: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + + T+ GH+ + +L + D R +S + +W V G+ + TG +
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227
Query: 1094 SIDVTL----NMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE---RITCFALTADS 1146
I+ +A SD D + R++ L ++ + SH IT + +
Sbjct: 228 DINAICFFPNGNAFATGSD-DATCRLFDL----RADQELMTYSHDNIICGITSVSFSKSG 282
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ ++ G D + VW + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 283 RLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 340
Score = 68.1 bits (159), Expect = 2e-10
Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + T GH G + ++ +P+ L +SG+
Sbjct: 146 LSCCRFLDDNQIVTSS-GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRR-AMSSDRAR-NVHVWLVDSGIVLH 1086
D + +W + + T+ GH S I + +G A SD A + D ++ +
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V+ + +L G D + +W D + H R++C +T
Sbjct: 265 SHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 322 DDGMAVATGSWDSFLKIW 339
Score = 63.3 bits (147), Expect = 6e-09
Identities = 46/201 (22%), Positives = 84/201 (41%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T T H V+ ++ + L
Sbjct: 141 GHTGYLSC-CRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT 811
+SG D++ + + +G H + ++ +GN F TGS D T +++
Sbjct: 200 VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 259
Query: 812 LLSTVT-AGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
L T + + I V+ L L G ++ + + + L H +V C
Sbjct: 260 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLKIWN 340
Score = 57.6 bits (133), Expect = 3e-07
Identities = 43/183 (23%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Query: 669 LAPSAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+ S+GD LW I + + TF GH+G ++ + + +++ ++G+ D S +WD+
Sbjct: 157 IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSV 784
+ H + + + N + +G DD+ + L D L+T D+ +TSV
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSV 276
Query: 785 KVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNE 842
+ G + + G D W+ + V AG + VTDD + + T D+
Sbjct: 277 SFSKSGRLLLAGYDDFNCNVWDALKAD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSF 335
Query: 843 LHL 845
L +
Sbjct: 336 LKI 338
Score = 56.0 bits (129), Expect = 9e-07
Identities = 50/257 (19%), Positives = 96/257 (37%), Gaps = 12/257 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSA--TGPSASIDVT--LNMKYAVLSDGDNS 1112
G D +++ G V S G + + L+ V S GD +
Sbjct: 106 APSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + G + H + +L D++ V+G+ D S K+W + G Q
Sbjct: 166 CALWDIETG---QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
GH + + N +GS D ++D+ +T V +
Sbjct: 223 TGHESDINAICF-FPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKS 281
Query: 1231 GTIAVSCAEDKTLIIWE 1247
G + ++ +D +W+
Sbjct: 282 GRLLLAGYDDFNCNVWD 298
Score = 54.8 bits (126), Expect = 2e-06
Identities = 50/215 (23%), Positives = 87/215 (40%), Gaps = 6/215 (2%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D I +T S D T
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAK 863
W++E +T T + + D ++ D L G H++
Sbjct: 169 WDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESD 228
Query: 864 VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ C + + A G D L+ L + Q L T
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMT 263
Score = 53.2 bits (122), Expect = 7e-06
Identities = 35/155 (22%), Positives = 62/155 (40%), Gaps = 5/155 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +KVH S ++ Y+ G D +++L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + +V S GD + + + G T H G V
Sbjct: 130 EGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA-LWDIETGQQTTTFTGHTGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
S+ + D +F++G+ D + W+V T T
Sbjct: 189 SLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFT 223
Score = 51.2 bits (117), Expect = 3e-05
Identities = 43/219 (19%), Positives = 95/219 (43%), Gaps = 8/219 (3%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
Y DN I++L + N +R H ++C D+Q +VT S D + +
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXXXXXXXX 1219
W ++ G+ + GH+ V +++S+ T++ VSG+ D + +WD+
Sbjct: 169 WDIETGQQTTTFTGHTGDV--MSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 1220 XKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D T +++ + L ++S
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS 265
Score = 50.4 bits (115), Expect = 5e-05
Identities = 58/291 (19%), Positives = 111/291 (38%), Gaps = 16/291 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNYVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDT-TCALWDIE 172
Query: 1081 SG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+G TG S+ + + + V D S ++W + G + H I
Sbjct: 173 TGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG---MCRQTFTGHESDI 229
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKTQVV-SG 1195
+ TGS D + +++ L + + H +I+ + +VS + +++ +G
Sbjct: 230 NAICFFPNGNAFATGSDDATCRLFDLRADQ-ELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
D N VWD +V+C+ VT DG + + D L IW
Sbjct: 289 YDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 49.6 bits (113), Expect = 8e-05
Identities = 38/151 (25%), Positives = 60/151 (39%), Gaps = 2/151 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP + V +LW + TF GH I +C TGS+D +
Sbjct: 190 LSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDAT 249
Query: 718 VIVWDLHT-LAVKTKILEH-IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
++DL + T ++ I + V+ + L+++G DD + + L
Sbjct: 250 CRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLA 309
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 310 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 49.2 bits (112), Expect = 1e-04
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A +V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 101 MTC-AYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN--QI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
V+ S D +WDI T V + + D + VS A D + +W+ + G+
Sbjct: 158 VTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGM 217
Query: 1253 ALTSFSLH 1260
+F+ H
Sbjct: 218 CRQTFTGH 225
>BC008991-1|AAH08991.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 77.4 bits (182), Expect = 4e-13
Identities = 60/239 (25%), Positives = 106/239 (44%), Gaps = 18/239 (7%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N +V S S D T
Sbjct: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + + T+ GH+ + +L + D R +S + +W V G+ + TG +
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227
Query: 1094 SIDVTL----NMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE---RITCFALTADS 1146
I+ +A SD D + R++ L ++ + SH IT + +
Sbjct: 228 DINAICFFPNGNAFATGSD-DATCRLFDL----RADQELMTYSHDNIICGITSVSFSKSG 282
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ ++ G D + VW + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 283 RLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 340
Score = 68.1 bits (159), Expect = 2e-10
Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + T GH G + ++ +P+ L +SG+
Sbjct: 146 LSCCRFLDDNQIVTSS-GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRR-AMSSDRAR-NVHVWLVDSGIVLH 1086
D + +W + + T+ GH S I + +G A SD A + D ++ +
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V+ + +L G D + +W D + H R++C +T
Sbjct: 265 SHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 322 DDGMAVATGSWDSFLKIW 339
Score = 63.3 bits (147), Expect = 6e-09
Identities = 46/201 (22%), Positives = 84/201 (41%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T T H V+ ++ + L
Sbjct: 141 GHTGYLSC-CRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT 811
+SG D++ + + +G H + ++ +GN F TGS D T +++
Sbjct: 200 VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 259
Query: 812 LLSTVT-AGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
L T + + I V+ L L G ++ + + + L H +V C
Sbjct: 260 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLKIWN 340
Score = 57.6 bits (133), Expect = 3e-07
Identities = 43/183 (23%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Query: 669 LAPSAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+ S+GD LW I + + TF GH+G ++ + + +++ ++G+ D S +WD+
Sbjct: 157 IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSV 784
+ H + + + N + +G DD+ + L D L+T D+ +TSV
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSV 276
Query: 785 KVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNE 842
+ G + + G D W+ + V AG + VTDD + + T D+
Sbjct: 277 SFSKSGRLLLAGYDDFNCNVWDALKAD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSF 335
Query: 843 LHL 845
L +
Sbjct: 336 LKI 338
Score = 56.0 bits (129), Expect = 9e-07
Identities = 50/257 (19%), Positives = 96/257 (37%), Gaps = 12/257 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSA--TGPSASIDVT--LNMKYAVLSDGDNS 1112
G D +++ G V S G + + L+ V S GD +
Sbjct: 106 APSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + G + H + +L D++ V+G+ D S K+W + G Q
Sbjct: 166 CALWDIETG---QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
GH + + N +GS D ++D+ +T V +
Sbjct: 223 TGHESDINAICF-FPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKS 281
Query: 1231 GTIAVSCAEDKTLIIWE 1247
G + ++ +D +W+
Sbjct: 282 GRLLLAGYDDFNCNVWD 298
Score = 54.8 bits (126), Expect = 2e-06
Identities = 50/215 (23%), Positives = 87/215 (40%), Gaps = 6/215 (2%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D I +T S D T
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAK 863
W++E +T T + + D ++ D L G H++
Sbjct: 169 WDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESD 228
Query: 864 VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ C + + A G D L+ L + Q L T
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMT 263
Score = 53.2 bits (122), Expect = 7e-06
Identities = 35/155 (22%), Positives = 62/155 (40%), Gaps = 5/155 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +KVH S ++ Y+ G D +++L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + +V S GD + + + G T H G V
Sbjct: 130 EGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA-LWDIETGQQTTTFTGHTGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
S+ + D +F++G+ D + W+V T T
Sbjct: 189 SLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFT 223
Score = 51.2 bits (117), Expect = 3e-05
Identities = 43/219 (19%), Positives = 95/219 (43%), Gaps = 8/219 (3%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
Y DN I++L + N +R H ++C D+Q +VT S D + +
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXXXXXXXX 1219
W ++ G+ + GH+ V +++S+ T++ VSG+ D + +WD+
Sbjct: 169 WDIETGQQTTTFTGHTGDV--MSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 1220 XKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D T +++ + L ++S
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS 265
Score = 50.4 bits (115), Expect = 5e-05
Identities = 58/291 (19%), Positives = 111/291 (38%), Gaps = 16/291 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNYVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDT-TCALWDIE 172
Query: 1081 SG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+G TG S+ + + + V D S ++W + G + H I
Sbjct: 173 TGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG---MCRQTFTGHESDI 229
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKTQVV-SG 1195
+ TGS D + +++ L + + H +I+ + +VS + +++ +G
Sbjct: 230 NAICFFPNGNAFATGSDDATCRLFDLRADQ-ELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
D N VWD +V+C+ VT DG + + D L IW
Sbjct: 289 YDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 49.6 bits (113), Expect = 8e-05
Identities = 38/151 (25%), Positives = 60/151 (39%), Gaps = 2/151 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP + V +LW + TF GH I +C TGS+D +
Sbjct: 190 LSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDAT 249
Query: 718 VIVWDLHT-LAVKTKILEH-IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
++DL + T ++ I + V+ + L+++G DD + + L
Sbjct: 250 CRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLA 309
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 310 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 49.2 bits (112), Expect = 1e-04
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A +V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 101 MTC-AYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN--QI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
V+ S D +WDI T V + + D + VS A D + +W+ + G+
Sbjct: 158 VTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGM 217
Query: 1253 ALTSFSLH 1260
+F+ H
Sbjct: 218 CRQTFTGH 225
>BC005888-1|AAH05888.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 77.4 bits (182), Expect = 4e-13
Identities = 60/239 (25%), Positives = 106/239 (44%), Gaps = 18/239 (7%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N +V S S D T
Sbjct: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + + T+ GH+ + +L + D R +S + +W V G+ + TG +
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227
Query: 1094 SIDVTL----NMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE---RITCFALTADS 1146
I+ +A SD D + R++ L ++ + SH IT + +
Sbjct: 228 DINAICFFPNGNAFATGSD-DATCRLFDL----RADQELMTYSHDNIICGITSVSFSKSG 282
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ ++ G D + VW + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 283 RLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 340
Score = 68.1 bits (159), Expect = 2e-10
Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + T GH G + ++ +P+ L +SG+
Sbjct: 146 LSCCRFLDDNQIVTSS-GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRR-AMSSDRAR-NVHVWLVDSGIVLH 1086
D + +W + + T+ GH S I + +G A SD A + D ++ +
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V+ + +L G D + +W D + H R++C +T
Sbjct: 265 SHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 322 DDGMAVATGSWDSFLKIW 339
Score = 63.3 bits (147), Expect = 6e-09
Identities = 46/201 (22%), Positives = 84/201 (41%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T T H V+ ++ + L
Sbjct: 141 GHTGYLSC-CRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT 811
+SG D++ + + +G H + ++ +GN F TGS D T +++
Sbjct: 200 VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 259
Query: 812 LLSTVT-AGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
L T + + I V+ L L G ++ + + + L H +V C
Sbjct: 260 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLKIWN 340
Score = 57.6 bits (133), Expect = 3e-07
Identities = 43/183 (23%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Query: 669 LAPSAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+ S+GD LW I + + TF GH+G ++ + + +++ ++G+ D S +WD+
Sbjct: 157 IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSV 784
+ H + + + N + +G DD+ + L D L+T D+ +TSV
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSV 276
Query: 785 KVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNE 842
+ G + + G D W+ + V AG + VTDD + + T D+
Sbjct: 277 SFSKSGRLLLAGYDDFNCNVWDALKAD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSF 335
Query: 843 LHL 845
L +
Sbjct: 336 LKI 338
Score = 56.0 bits (129), Expect = 9e-07
Identities = 50/257 (19%), Positives = 96/257 (37%), Gaps = 12/257 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSA--TGPSASIDVT--LNMKYAVLSDGDNS 1112
G D +++ G V S G + + L+ V S GD +
Sbjct: 106 APSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + G + H + +L D++ V+G+ D S K+W + G Q
Sbjct: 166 CALWDIETG---QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
GH + + N +GS D ++D+ +T V +
Sbjct: 223 TGHESDINAICF-FPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKS 281
Query: 1231 GTIAVSCAEDKTLIIWE 1247
G + ++ +D +W+
Sbjct: 282 GRLLLAGYDDFNCNVWD 298
Score = 54.8 bits (126), Expect = 2e-06
Identities = 50/215 (23%), Positives = 87/215 (40%), Gaps = 6/215 (2%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D I +T S D T
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAK 863
W++E +T T + + D ++ D L G H++
Sbjct: 169 WDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESD 228
Query: 864 VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ C + + A G D L+ L + Q L T
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMT 263
Score = 53.2 bits (122), Expect = 7e-06
Identities = 35/155 (22%), Positives = 62/155 (40%), Gaps = 5/155 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +KVH S ++ Y+ G D +++L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + +V S GD + + + G T H G V
Sbjct: 130 EGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA-LWDIETGQQTTTFTGHTGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
S+ + D +F++G+ D + W+V T T
Sbjct: 189 SLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFT 223
Score = 51.2 bits (117), Expect = 3e-05
Identities = 43/219 (19%), Positives = 95/219 (43%), Gaps = 8/219 (3%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
Y DN I++L + N +R H ++C D+Q +VT S D + +
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXXXXXXXX 1219
W ++ G+ + GH+ V +++S+ T++ VSG+ D + +WD+
Sbjct: 169 WDIETGQQTTTFTGHTGDV--MSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 1220 XKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D T +++ + L ++S
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS 265
Score = 50.4 bits (115), Expect = 5e-05
Identities = 58/291 (19%), Positives = 111/291 (38%), Gaps = 16/291 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNYVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDT-TCALWDIE 172
Query: 1081 SG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+G TG S+ + + + V D S ++W + G + H I
Sbjct: 173 TGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG---MCRQTFTGHESDI 229
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKTQVV-SG 1195
+ TGS D + +++ L + + H +I+ + +VS + +++ +G
Sbjct: 230 NAICFFPNGNAFATGSDDATCRLFDLRADQ-ELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
D N VWD +V+C+ VT DG + + D L IW
Sbjct: 289 YDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 49.6 bits (113), Expect = 8e-05
Identities = 38/151 (25%), Positives = 60/151 (39%), Gaps = 2/151 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP + V +LW + TF GH I +C TGS+D +
Sbjct: 190 LSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDAT 249
Query: 718 VIVWDLHT-LAVKTKILEH-IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
++DL + T ++ I + V+ + L+++G DD + + L
Sbjct: 250 CRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLA 309
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 310 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 49.2 bits (112), Expect = 1e-04
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A +V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 101 MTC-AYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN--QI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
V+ S D +WDI T V + + D + VS A D + +W+ + G+
Sbjct: 158 VTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGM 217
Query: 1253 ALTSFSLH 1260
+F+ H
Sbjct: 218 CRQTFTGH 225
>BC004186-1|AAH04186.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 77.4 bits (182), Expect = 4e-13
Identities = 60/239 (25%), Positives = 106/239 (44%), Gaps = 18/239 (7%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N +V S S D T
Sbjct: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + + T+ GH+ + +L + D R +S + +W V G+ + TG +
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227
Query: 1094 SIDVTL----NMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE---RITCFALTADS 1146
I+ +A SD D + R++ L ++ + SH IT + +
Sbjct: 228 DINAICFFPNGNAFATGSD-DATCRLFDL----RADQELMTYSHDNIICGITSVSFSKSG 282
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ ++ G D + VW + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 283 RLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 340
Score = 68.1 bits (159), Expect = 2e-10
Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + T GH G + ++ +P+ L +SG+
Sbjct: 146 LSCCRFLDDNQIVTSS-GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRR-AMSSDRAR-NVHVWLVDSGIVLH 1086
D + +W + + T+ GH S I + +G A SD A + D ++ +
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V+ + +L G D + +W D + H R++C +T
Sbjct: 265 SHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 322 DDGMAVATGSWDSFLKIW 339
Score = 63.3 bits (147), Expect = 6e-09
Identities = 46/201 (22%), Positives = 84/201 (41%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T T H V+ ++ + L
Sbjct: 141 GHTGYLSC-CRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT 811
+SG D++ + + +G H + ++ +GN F TGS D T +++
Sbjct: 200 VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 259
Query: 812 LLSTVT-AGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
L T + + I V+ L L G ++ + + + L H +V C
Sbjct: 260 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLKIWN 340
Score = 57.6 bits (133), Expect = 3e-07
Identities = 43/183 (23%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Query: 669 LAPSAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+ S+GD LW I + + TF GH+G ++ + + +++ ++G+ D S +WD+
Sbjct: 157 IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSV 784
+ H + + + N + +G DD+ + L D L+T D+ +TSV
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSV 276
Query: 785 KVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNE 842
+ G + + G D W+ + V AG + VTDD + + T D+
Sbjct: 277 SFSKSGRLLLAGYDDFNCNVWDALKAD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSF 335
Query: 843 LHL 845
L +
Sbjct: 336 LKI 338
Score = 56.0 bits (129), Expect = 9e-07
Identities = 50/257 (19%), Positives = 96/257 (37%), Gaps = 12/257 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSA--TGPSASIDVT--LNMKYAVLSDGDNS 1112
G D +++ G V S G + + L+ V S GD +
Sbjct: 106 APSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + G + H + +L D++ V+G+ D S K+W + G Q
Sbjct: 166 CALWDIETG---QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
GH + + N +GS D ++D+ +T V +
Sbjct: 223 TGHESDINAICF-FPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKS 281
Query: 1231 GTIAVSCAEDKTLIIWE 1247
G + ++ +D +W+
Sbjct: 282 GRLLLAGYDDFNCNVWD 298
Score = 54.8 bits (126), Expect = 2e-06
Identities = 50/215 (23%), Positives = 87/215 (40%), Gaps = 6/215 (2%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D I +T S D T
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAK 863
W++E +T T + + D ++ D L G H++
Sbjct: 169 WDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESD 228
Query: 864 VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ C + + A G D L+ L + Q L T
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMT 263
Score = 53.2 bits (122), Expect = 7e-06
Identities = 35/155 (22%), Positives = 62/155 (40%), Gaps = 5/155 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +KVH S ++ Y+ G D +++L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + +V S GD + + + G T H G V
Sbjct: 130 EGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA-LWDIETGQQTTTFTGHTGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
S+ + D +F++G+ D + W+V T T
Sbjct: 189 SLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFT 223
Score = 51.2 bits (117), Expect = 3e-05
Identities = 43/219 (19%), Positives = 95/219 (43%), Gaps = 8/219 (3%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
Y DN I++L + N +R H ++C D+Q +VT S D + +
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXXXXXXXX 1219
W ++ G+ + GH+ V +++S+ T++ VSG+ D + +WD+
Sbjct: 169 WDIETGQQTTTFTGHTGDV--MSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 1220 XKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D T +++ + L ++S
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS 265
Score = 50.4 bits (115), Expect = 5e-05
Identities = 58/291 (19%), Positives = 111/291 (38%), Gaps = 16/291 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNYVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDT-TCALWDIE 172
Query: 1081 SG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+G TG S+ + + + V D S ++W + G + H I
Sbjct: 173 TGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG---MCRQTFTGHESDI 229
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKTQVV-SG 1195
+ TGS D + +++ L + + H +I+ + +VS + +++ +G
Sbjct: 230 NAICFFPNGNAFATGSDDATCRLFDLRADQ-ELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
D N VWD +V+C+ VT DG + + D L IW
Sbjct: 289 YDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 49.6 bits (113), Expect = 8e-05
Identities = 38/151 (25%), Positives = 60/151 (39%), Gaps = 2/151 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP + V +LW + TF GH I +C TGS+D +
Sbjct: 190 LSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDAT 249
Query: 718 VIVWDLHT-LAVKTKILEH-IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
++DL + T ++ I + V+ + L+++G DD + + L
Sbjct: 250 CRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLA 309
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 310 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 49.2 bits (112), Expect = 1e-04
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A +V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 101 MTC-AYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN--QI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
V+ S D +WDI T V + + D + VS A D + +W+ + G+
Sbjct: 158 VTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGM 217
Query: 1253 ALTSFSLH 1260
+F+ H
Sbjct: 218 CRQTFTGH 225
>AL109917-5|CAI95654.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 77.4 bits (182), Expect = 4e-13
Identities = 60/239 (25%), Positives = 106/239 (44%), Gaps = 18/239 (7%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N +V S S D T
Sbjct: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + + T+ GH+ + +L + D R +S + +W V G+ + TG +
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227
Query: 1094 SIDVTL----NMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE---RITCFALTADS 1146
I+ +A SD D + R++ L ++ + SH IT + +
Sbjct: 228 DINAICFFPNGNAFATGSD-DATCRLFDL----RADQELMTYSHDNIICGITSVSFSKSG 282
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ ++ G D + VW + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 283 RLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 340
Score = 68.1 bits (159), Expect = 2e-10
Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + T GH G + ++ +P+ L +SG+
Sbjct: 146 LSCCRFLDDNQIVTSS-GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRR-AMSSDRAR-NVHVWLVDSGIVLH 1086
D + +W + + T+ GH S I + +G A SD A + D ++ +
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V+ + +L G D + +W D + H R++C +T
Sbjct: 265 SHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 322 DDGMAVATGSWDSFLKIW 339
Score = 63.3 bits (147), Expect = 6e-09
Identities = 46/201 (22%), Positives = 84/201 (41%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T T H V+ ++ + L
Sbjct: 141 GHTGYLSC-CRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT 811
+SG D++ + + +G H + ++ +GN F TGS D T +++
Sbjct: 200 VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 259
Query: 812 LLSTVT-AGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
L T + + I V+ L L G ++ + + + L H +V C
Sbjct: 260 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLKIWN 340
Score = 57.6 bits (133), Expect = 3e-07
Identities = 43/183 (23%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Query: 669 LAPSAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+ S+GD LW I + + TF GH+G ++ + + +++ ++G+ D S +WD+
Sbjct: 157 IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSV 784
+ H + + + N + +G DD+ + L D L+T D+ +TSV
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSV 276
Query: 785 KVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNE 842
+ G + + G D W+ + V AG + VTDD + + T D+
Sbjct: 277 SFSKSGRLLLAGYDDFNCNVWDALKAD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSF 335
Query: 843 LHL 845
L +
Sbjct: 336 LKI 338
Score = 56.0 bits (129), Expect = 9e-07
Identities = 50/257 (19%), Positives = 96/257 (37%), Gaps = 12/257 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSA--TGPSASIDVT--LNMKYAVLSDGDNS 1112
G D +++ G V S G + + L+ V S GD +
Sbjct: 106 APSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + G + H + +L D++ V+G+ D S K+W + G Q
Sbjct: 166 CALWDIETG---QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
GH + + N +GS D ++D+ +T V +
Sbjct: 223 TGHESDINAICF-FPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKS 281
Query: 1231 GTIAVSCAEDKTLIIWE 1247
G + ++ +D +W+
Sbjct: 282 GRLLLAGYDDFNCNVWD 298
Score = 54.8 bits (126), Expect = 2e-06
Identities = 50/215 (23%), Positives = 87/215 (40%), Gaps = 6/215 (2%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D I +T S D T
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAK 863
W++E +T T + + D ++ D L G H++
Sbjct: 169 WDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESD 228
Query: 864 VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ C + + A G D L+ L + Q L T
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMT 263
Score = 53.2 bits (122), Expect = 7e-06
Identities = 35/155 (22%), Positives = 62/155 (40%), Gaps = 5/155 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +KVH S ++ Y+ G D +++L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + +V S GD + + + G T H G V
Sbjct: 130 EGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA-LWDIETGQQTTTFTGHTGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
S+ + D +F++G+ D + W+V T T
Sbjct: 189 SLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFT 223
Score = 51.2 bits (117), Expect = 3e-05
Identities = 43/219 (19%), Positives = 95/219 (43%), Gaps = 8/219 (3%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
Y DN I++L + N +R H ++C D+Q +VT S D + +
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXXXXXXXX 1219
W ++ G+ + GH+ V +++S+ T++ VSG+ D + +WD+
Sbjct: 169 WDIETGQQTTTFTGHTGDV--MSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 1220 XKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D T +++ + L ++S
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS 265
Score = 50.4 bits (115), Expect = 5e-05
Identities = 58/291 (19%), Positives = 111/291 (38%), Gaps = 16/291 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNYVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDT-TCALWDIE 172
Query: 1081 SG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+G TG S+ + + + V D S ++W + G + H I
Sbjct: 173 TGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG---MCRQTFTGHESDI 229
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKTQVV-SG 1195
+ TGS D + +++ L + + H +I+ + +VS + +++ +G
Sbjct: 230 NAICFFPNGNAFATGSDDATCRLFDLRADQ-ELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
D N VWD +V+C+ VT DG + + D L IW
Sbjct: 289 YDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 49.6 bits (113), Expect = 8e-05
Identities = 38/151 (25%), Positives = 60/151 (39%), Gaps = 2/151 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP + V +LW + TF GH I +C TGS+D +
Sbjct: 190 LSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDAT 249
Query: 718 VIVWDLHT-LAVKTKILEH-IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
++DL + T ++ I + V+ + L+++G DD + + L
Sbjct: 250 CRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLA 309
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 310 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 49.2 bits (112), Expect = 1e-04
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A +V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 101 MTC-AYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN--QI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
V+ S D +WDI T V + + D + VS A D + +W+ + G+
Sbjct: 158 VTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGM 217
Query: 1253 ALTSFSLH 1260
+F+ H
Sbjct: 218 CRQTFTGH 225
>AL031282-2|CAI20029.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 77.4 bits (182), Expect = 4e-13
Identities = 60/239 (25%), Positives = 106/239 (44%), Gaps = 18/239 (7%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N +V S S D T
Sbjct: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + + T+ GH+ + +L + D R +S + +W V G+ + TG +
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227
Query: 1094 SIDVTL----NMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE---RITCFALTADS 1146
I+ +A SD D + R++ L ++ + SH IT + +
Sbjct: 228 DINAICFFPNGNAFATGSD-DATCRLFDL----RADQELMTYSHDNIICGITSVSFSKSG 282
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ ++ G D + VW + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 283 RLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 340
Score = 68.1 bits (159), Expect = 2e-10
Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + T GH G + ++ +P+ L +SG+
Sbjct: 146 LSCCRFLDDNQIVTSS-GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRR-AMSSDRAR-NVHVWLVDSGIVLH 1086
D + +W + + T+ GH S I + +G A SD A + D ++ +
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V+ + +L G D + +W D + H R++C +T
Sbjct: 265 SHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 322 DDGMAVATGSWDSFLKIW 339
Score = 63.3 bits (147), Expect = 6e-09
Identities = 46/201 (22%), Positives = 84/201 (41%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T T H V+ ++ + L
Sbjct: 141 GHTGYLSC-CRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT 811
+SG D++ + + +G H + ++ +GN F TGS D T +++
Sbjct: 200 VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 259
Query: 812 LLSTVT-AGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
L T + + I V+ L L G ++ + + + L H +V C
Sbjct: 260 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLKIWN 340
Score = 57.6 bits (133), Expect = 3e-07
Identities = 43/183 (23%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Query: 669 LAPSAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+ S+GD LW I + + TF GH+G ++ + + +++ ++G+ D S +WD+
Sbjct: 157 IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSV 784
+ H + + + N + +G DD+ + L D L+T D+ +TSV
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSV 276
Query: 785 KVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNE 842
+ G + + G D W+ + V AG + VTDD + + T D+
Sbjct: 277 SFSKSGRLLLAGYDDFNCNVWDALKAD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSF 335
Query: 843 LHL 845
L +
Sbjct: 336 LKI 338
Score = 56.0 bits (129), Expect = 9e-07
Identities = 50/257 (19%), Positives = 96/257 (37%), Gaps = 12/257 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSA--TGPSASIDVT--LNMKYAVLSDGDNS 1112
G D +++ G V S G + + L+ V S GD +
Sbjct: 106 APSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + G + H + +L D++ V+G+ D S K+W + G Q
Sbjct: 166 CALWDIETG---QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
GH + + N +GS D ++D+ +T V +
Sbjct: 223 TGHESDINAICF-FPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKS 281
Query: 1231 GTIAVSCAEDKTLIIWE 1247
G + ++ +D +W+
Sbjct: 282 GRLLLAGYDDFNCNVWD 298
Score = 54.8 bits (126), Expect = 2e-06
Identities = 50/215 (23%), Positives = 87/215 (40%), Gaps = 6/215 (2%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D I +T S D T
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAK 863
W++E +T T + + D ++ D L G H++
Sbjct: 169 WDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESD 228
Query: 864 VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ C + + A G D L+ L + Q L T
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMT 263
Score = 53.2 bits (122), Expect = 7e-06
Identities = 35/155 (22%), Positives = 62/155 (40%), Gaps = 5/155 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +KVH S ++ Y+ G D +++L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + +V S GD + + + G T H G V
Sbjct: 130 EGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA-LWDIETGQQTTTFTGHTGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
S+ + D +F++G+ D + W+V T T
Sbjct: 189 SLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFT 223
Score = 51.2 bits (117), Expect = 3e-05
Identities = 43/219 (19%), Positives = 95/219 (43%), Gaps = 8/219 (3%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
Y DN I++L + N +R H ++C D+Q +VT S D + +
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXXXXXXXX 1219
W ++ G+ + GH+ V +++S+ T++ VSG+ D + +WD+
Sbjct: 169 WDIETGQQTTTFTGHTGDV--MSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 1220 XKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D T +++ + L ++S
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS 265
Score = 50.4 bits (115), Expect = 5e-05
Identities = 58/291 (19%), Positives = 111/291 (38%), Gaps = 16/291 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNYVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDT-TCALWDIE 172
Query: 1081 SG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+G TG S+ + + + V D S ++W + G + H I
Sbjct: 173 TGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG---MCRQTFTGHESDI 229
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKTQVV-SG 1195
+ TGS D + +++ L + + H +I+ + +VS + +++ +G
Sbjct: 230 NAICFFPNGNAFATGSDDATCRLFDLRADQ-ELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
D N VWD +V+C+ VT DG + + D L IW
Sbjct: 289 YDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 49.6 bits (113), Expect = 8e-05
Identities = 38/151 (25%), Positives = 60/151 (39%), Gaps = 2/151 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP + V +LW + TF GH I +C TGS+D +
Sbjct: 190 LSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDAT 249
Query: 718 VIVWDLHT-LAVKTKILEH-IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
++DL + T ++ I + V+ + L+++G DD + + L
Sbjct: 250 CRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLA 309
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 310 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 49.2 bits (112), Expect = 1e-04
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A +V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 101 MTC-AYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN--QI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
V+ S D +WDI T V + + D + VS A D + +W+ + G+
Sbjct: 158 VTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGM 217
Query: 1253 ALTSFSLH 1260
+F+ H
Sbjct: 218 CRQTFTGH 225
>AJ243010-1|CAB55586.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 77.4 bits (182), Expect = 4e-13
Identities = 96/460 (20%), Positives = 177/460 (38%), Gaps = 37/460 (8%)
Query: 828 TDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRV--AVGCADQRI 885
TDD F+ T D ++ + +TG +H H +V C + S + A G +D +
Sbjct: 667 TDDR-FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFL 725
Query: 886 YLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQM 945
L+ L+ + T LLA S + L + T
Sbjct: 726 KLWDLNQKECRNTMFGHTNSANHCRFSPDDKLLA---------SCSADGTLKLWDATSAN 776
Query: 946 KRRQTKSTTNITLLQAEQSDL-IPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATL 1004
+R+ L+ Q D+ + + C S DG A+ + +W + A
Sbjct: 777 ERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGAR-IMVAAKNKIFLWNTDSRSKVADC 835
Query: 1005 NGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQ---LADNSPSLTYKGHSSAIQTLLMMSD 1061
GH+ + V FSP+ L+ S+D+T+ +W+ + NS + + Q +M
Sbjct: 836 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVM-- 893
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGG 1121
++ D R + + +G + + + ++ +++Y D + ++ I L
Sbjct: 894 ---VLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELV-- 948
Query: 1122 DNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTC 1181
N+ + H + + TAD + +++ S D ++VW K L GH + T
Sbjct: 949 -NNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCI-FLRGHQE--TV 1004
Query: 1182 VAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDK 1241
+ ++++S S+D + VW+I T V ++ D T S + DK
Sbjct: 1005 KDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADK 1064
Query: 1242 TLIIWETKRGLALTSFSLHVPLLGFQITSDCARVVVHLLD 1281
T IW SF L +PL + + C R +D
Sbjct: 1065 TAKIW---------SFDLLLPLHELRGHNGCVRCSAFSVD 1095
Score = 62.1 bits (144), Expect = 1e-08
Identities = 34/147 (23%), Positives = 63/147 (42%), Gaps = 1/147 (0%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKT 1190
+H + + C A + D + + T S+D +K+W G+L HS+ V C + ++
Sbjct: 655 AHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHL 714
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
+ +GS DC L +WD+N + + D + SC+ D TL +W+
Sbjct: 715 LLATGSSDCFLKLWDLNQKECRNTMFGHTNSANHCRFSPDDKLLASCSADGTLKLWDATS 774
Query: 1251 GLALTSFSLHVPLLGFQITSDCARVVV 1277
S ++ L + + V+V
Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIV 801
Score = 53.6 bits (123), Expect = 5e-06
Identities = 42/202 (20%), Positives = 91/202 (45%), Gaps = 5/202 (2%)
Query: 697 ILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGD 756
+ C C++ QY+ G E+ ++ + +L + +H V + + +IS D
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 757 DSAVIITSL-VDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLST 815
D+ + + + +D + L H+ +V +++++ + ++ S DGTV WN+
Sbjct: 981 DAEIQVWNWQLDKCIF--LRGHQETVKDFRLLKNSRL-LSWSFDGTVKVWNIITGNKEKD 1037
Query: 816 -VTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSS 874
V + D++ D + D + +F LH L+ H V+C + DS+
Sbjct: 1038 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST 1097
Query: 875 RVAVGCADQRIYLYSLHSAQLL 896
+A G + I ++++ + +LL
Sbjct: 1098 LLATGDDNGEIRIWNVSNGELL 1119
Score = 52.0 bits (119), Expect = 2e-05
Identities = 44/205 (21%), Positives = 86/205 (41%), Gaps = 12/205 (5%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC +S Q A G G + + +L +R+ + H + + F+ + ++S S+
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSG-----I 1083
D + VW + + +GH ++ ++ + R +S V VW + +G
Sbjct: 981 DAEIQVWNWQLDK-CIFLRGHQETVKDFRLLKNSR-LLSWSFDGTVKVWNIITGNKEKDF 1038
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
V H T S D++ + + D + +IWS D H + C A +
Sbjct: 1039 VCHQGT--VLSCDISHDATKFSSTSADKTAKIWSF---DLLLPLHELRGHNGCVRCSAFS 1093
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKL 1168
DS + TG + +++W + G+L
Sbjct: 1094 VDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 49.6 bits (113), Expect = 8e-05
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 10/142 (7%)
Query: 674 GDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKIL 733
G ++W+I++ +K F H G++L ++ ++ + S D + +W L ++
Sbjct: 1022 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1081
Query: 734 EHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALV---TKLDH-----HRGSVTSVK 785
H V C A V+ +L+ +G D+ + I ++ +G L+ L H G VT +
Sbjct: 1082 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1141
Query: 786 VIQDGNIFITGSQDGTVCTWNV 807
DG + I S G + WNV
Sbjct: 1142 FSPDGKMLI--SAGGYIKWWNV 1161
Score = 44.4 bits (100), Expect = 0.003
Identities = 50/272 (18%), Positives = 105/272 (38%), Gaps = 23/272 (8%)
Query: 997 THRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTL 1056
T+ + + H + FS + + S D+T+ V++ L K H +
Sbjct: 604 TNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCC 663
Query: 1057 LMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID---VTLNMKYAVLSDG--DN 1111
+D R + + V +W +G ++H+ S ++ T + + +L+ G D
Sbjct: 664 AFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDC 723
Query: 1112 SVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGG----- 1166
+++W L + E H + D + + + S D +LK+W
Sbjct: 724 FLKLWDL---NQKECRNTMFGHTNSANHCRFSPDDKLLASCSADGTLKLWDATSANERKS 780
Query: 1167 -KLSQVLVGHSD-------IVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXX 1218
+ Q + D IV C + S +V+ + +W+ ++
Sbjct: 781 INVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAK--NKIFLWNTDSRSKVADCRGH 838
Query: 1219 XXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
V V + DG+ ++ ++D+T+ +WETK+
Sbjct: 839 LSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK 870
Score = 42.3 bits (95), Expect = 0.012
Identities = 32/146 (21%), Positives = 57/146 (39%), Gaps = 4/146 (2%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
GQ + + Q++ + K+ K H +LC + + +++ T S D V +W+
Sbjct: 627 GQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNS 686
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRS---LVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
T + EH V C N S L+ +G D + + L + H S
Sbjct: 687 MTGELVHTYDEHSEQVNC-CHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNS 745
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWN 806
+ D + + S DGT+ W+
Sbjct: 746 ANHCRFSPDDKLLASCSADGTLKLWD 771
Score = 42.3 bits (95), Expect = 0.012
Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 9/147 (6%)
Query: 988 GLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYK 1047
G V+VW + T + H G + S + S S D+T +W P +
Sbjct: 1022 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1081
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH---------SATGPSASIDVT 1098
GH+ ++ D + D + +W V +G +LH +AT D+
Sbjct: 1082 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1141
Query: 1099 LNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+ +L ++ W++ G++S+
Sbjct: 1142 FSPDGKMLISAGGYIKWWNVVTGESSQ 1168
Score = 41.1 bits (92), Expect = 0.028
Identities = 40/199 (20%), Positives = 79/199 (39%), Gaps = 7/199 (3%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
L+P Q++ G ++ +++N + H ++ + T + + L++ S+D +
Sbjct: 926 LSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQ 985
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
VW+ K L + ++ S ++S D V + +++ G H+G
Sbjct: 986 VWNWQ--LDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1043
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV---TAGVPIHIFDVTDDNVFLLT 836
+V S + D F + S D T W+ + L + V F V D+ L T
Sbjct: 1044 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSV--DSTLLAT 1101
Query: 837 LQGDNELHLRTFITGTYLH 855
+ E+ + G LH
Sbjct: 1102 GDDNGEIRIWNVSNGELLH 1120
Score = 40.7 bits (91), Expect = 0.038
Identities = 30/129 (23%), Positives = 53/129 (41%), Gaps = 3/129 (2%)
Query: 951 KSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGH 1010
K+ T LL+ + + + C S D + A+ V++W T L T + H
Sbjct: 643 KAETGEKLLEIKAHE-DEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQ 701
Query: 1011 ITCVTF--SPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSS 1068
+ C F S ++LL+ +GS D + +W L T GH+++ D + S
Sbjct: 702 VNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSANHCRFSPDDKLLASC 761
Query: 1069 DRARNVHVW 1077
+ +W
Sbjct: 762 SADGTLKLW 770
Score = 40.3 bits (90), Expect = 0.050
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 3/104 (2%)
Query: 951 KSTTNIT-LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIG 1009
K+ TN++ L+ +D + +C S DGQ AS A ++V++ T + H
Sbjct: 601 KNITNLSRLVVRPHTDAVYHACF--SEDGQRIASCGADKTLQVFKAETGEKLLEIKAHED 658
Query: 1010 HITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
+ C FS ++ + + S D+ V +W TY HS +
Sbjct: 659 EVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQV 702
Score = 35.1 bits (77), Expect = 1.9
Identities = 26/117 (22%), Positives = 47/117 (40%), Gaps = 2/117 (1%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ ++ C + + Q + + D ++ V+ T +I H VLC A + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
+ D V I + + G LV D H V + + TGS D + W++
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
>AF501882-1|AAM15918.1| 340|Homo sapiens guanine nucleotide binding
protein beta 1 protein.
Length = 340
Score = 77.4 bits (182), Expect = 4e-13
Identities = 60/239 (25%), Positives = 106/239 (44%), Gaps = 18/239 (7%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N +V S S D T
Sbjct: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + + T+ GH+ + +L + D R +S + +W V G+ + TG +
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227
Query: 1094 SIDVTL----NMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE---RITCFALTADS 1146
I+ +A SD D + R++ L ++ + SH IT + +
Sbjct: 228 DINAICFFPNGNAFATGSD-DATCRLFDL----RADQELMTYSHDNIICGITSVSFSKSG 282
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ ++ G D + VW + VL GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 283 RLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 340
Score = 68.1 bits (159), Expect = 2e-10
Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + T GH G + ++ +P+ L +SG+
Sbjct: 146 LSCCRFLDDNQIVTSS-GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRR-AMSSDRAR-NVHVWLVDSGIVLH 1086
D + +W + + T+ GH S I + +G A SD A + D ++ +
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V+ + +L G D + +W D + H R++C +T
Sbjct: 265 SHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 322 DDGMAVATGSWDSFLKIW 339
Score = 63.3 bits (147), Expect = 6e-09
Identities = 46/201 (22%), Positives = 84/201 (41%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T T H V+ ++ + L
Sbjct: 141 GHTGYLSC-CRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT 811
+SG D++ + + +G H + ++ +GN F TGS D T +++
Sbjct: 200 VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 259
Query: 812 LLSTVT-AGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
L T + + I V+ L L G ++ + + + L H +V C
Sbjct: 260 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 320 VTDDGMAVATGSWDSFLKIWN 340
Score = 57.6 bits (133), Expect = 3e-07
Identities = 43/183 (23%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Query: 669 LAPSAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+ S+GD LW I + + TF GH+G ++ + + +++ ++G+ D S +WD+
Sbjct: 157 IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSV 784
+ H + + + N + +G DD+ + L D L+T D+ +TSV
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSV 276
Query: 785 KVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNE 842
+ G + + G D W+ + V AG + VTDD + + T D+
Sbjct: 277 SFSKSGRLLLAGYDDFNCNVWDALKAD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSF 335
Query: 843 LHL 845
L +
Sbjct: 336 LKI 338
Score = 56.0 bits (129), Expect = 9e-07
Identities = 50/257 (19%), Positives = 96/257 (37%), Gaps = 12/257 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSA--TGPSASIDVT--LNMKYAVLSDGDNS 1112
G D +++ G V S G + + L+ V S GD +
Sbjct: 106 APSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + G + H + +L D++ V+G+ D S K+W + G Q
Sbjct: 166 CALWDIETG---QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
GH + + N +GS D ++D+ +T V +
Sbjct: 223 TGHESDINAICF-FPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKS 281
Query: 1231 GTIAVSCAEDKTLIIWE 1247
G + ++ +D +W+
Sbjct: 282 GRLLLAGYDDFNCNVWD 298
Score = 54.8 bits (126), Expect = 2e-06
Identities = 50/215 (23%), Positives = 87/215 (40%), Gaps = 6/215 (2%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D I +T S D T
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAK 863
W++E +T T + + D ++ D L G H++
Sbjct: 169 WDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESD 228
Query: 864 VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ C + + A G D L+ L + Q L T
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMT 263
Score = 53.2 bits (122), Expect = 7e-06
Identities = 35/155 (22%), Positives = 62/155 (40%), Gaps = 5/155 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +KVH S ++ Y+ G D +++L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + +V S GD + + + G T H G V
Sbjct: 130 EGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA-LWDIETGQQTTTFTGHTGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
S+ + D +F++G+ D + W+V T T
Sbjct: 189 SLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFT 223
Score = 51.2 bits (117), Expect = 3e-05
Identities = 43/219 (19%), Positives = 95/219 (43%), Gaps = 8/219 (3%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
Y DN I++L + N +R H ++C D+Q +VT S D + +
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXXXXXXXX 1219
W ++ G+ + GH+ V +++S+ T++ VSG+ D + +WD+
Sbjct: 169 WDIETGQQTTTFTGHTGDV--MSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 1220 XKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D T +++ + L ++S
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS 265
Score = 50.4 bits (115), Expect = 5e-05
Identities = 58/291 (19%), Positives = 111/291 (38%), Gaps = 16/291 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNYVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDT-TCALWDIE 172
Query: 1081 SG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+G TG S+ + + + V D S ++W + G + H I
Sbjct: 173 TGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG---MCRQTFTGHESDI 229
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKTQVV-SG 1195
+ TGS D + +++ L + + H +I+ + +VS + +++ +G
Sbjct: 230 NAICFFPNGNAFATGSDDATCRLFDLRADQ-ELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
D N VWD +V+C+ VT DG + + D L IW
Sbjct: 289 YDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 49.6 bits (113), Expect = 8e-05
Identities = 38/151 (25%), Positives = 60/151 (39%), Gaps = 2/151 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP + V +LW + TF GH I +C TGS+D +
Sbjct: 190 LSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDAT 249
Query: 718 VIVWDLHT-LAVKTKILEH-IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
++DL + T ++ I + V+ + L+++G DD + + L
Sbjct: 250 CRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLA 309
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 310 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 49.2 bits (112), Expect = 1e-04
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A +V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 101 MTC-AYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN--QI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
V+ S D +WDI T V + + D + VS A D + +W+ + G+
Sbjct: 158 VTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGM 217
Query: 1253 ALTSFSLH 1260
+F+ H
Sbjct: 218 CRQTFTGH 225
>BC035409-1|AAH35409.1| 808|Homo sapiens transducin (beta)-like 3
protein.
Length = 808
Score = 77.0 bits (181), Expect = 5e-13
Identities = 69/300 (23%), Positives = 121/300 (40%), Gaps = 20/300 (6%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPN--NLLVLS 1025
P++ + L A+G G VRVW + H G G + V F P+ LL+ S
Sbjct: 111 PVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFS 170
Query: 1026 GSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW-------- 1077
+ D + VW L D S H SA+ +L +DG +SS R + +W
Sbjct: 171 SATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQAT 230
Query: 1078 -------LVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
V++ ++L P + + V Y + + ++R+W A G +
Sbjct: 231 RTVPVFESVEAAVLLPEE--PVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQP 288
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKT 1190
+ +T L + V+T + D +L +++ +L + G+S+ V V +
Sbjct: 289 PGPGQELTHCTLAHTAGVVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDS 348
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
VV S L V+++ T V + V G + SCA+D+++ IW +
Sbjct: 349 HVVVASNSPCLKVFELQTSACQILHGHTDI-VLALDVFRKGWLFASCAKDQSVRIWRMNK 407
Score = 61.7 bits (143), Expect = 2e-08
Identities = 36/140 (25%), Positives = 69/140 (49%), Gaps = 3/140 (2%)
Query: 943 KQMKRRQTKSTTNITLLQAEQSDLI---PISCLEVSRDGQLGASGCARGLVRVWQLSTHR 999
K + + T LLQA+ + I+ + ++ + +L A+G ++W L +
Sbjct: 453 KALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQ 512
Query: 1000 LQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
L +GH + CV FSP + ++ + S D T+ +W L D S T++GH +++ + +
Sbjct: 513 LLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFV 572
Query: 1060 SDGRRAMSSDRARNVHVWLV 1079
S G + +SS V +W +
Sbjct: 573 SRGTQLLSSGSDGLVKLWTI 592
Score = 58.4 bits (135), Expect = 2e-07
Identities = 36/146 (24%), Positives = 62/146 (42%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
+AP+ + L +LW + + F GH + C+ + Q L T S D ++
Sbjct: 487 IAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIK 546
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
+W L + H A VL VA + + ++S G D V + ++ + V LD H
Sbjct: 547 LWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHED 606
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTW 805
V + + + +TG+ D V W
Sbjct: 607 KVWGLHCSRLDDHALTGASDSRVILW 632
Score = 53.6 bits (123), Expect = 5e-06
Identities = 38/165 (23%), Positives = 72/165 (43%), Gaps = 6/165 (3%)
Query: 1001 QATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMS 1060
Q T H I V +PN+ L+ +GS+DRT +W L + GH + +
Sbjct: 472 QTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSP 531
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI--DVTLNMKYAVLSDG-DNSVRIWS 1117
+ ++ + +W + L + G AS+ ++ +LS G D V++W+
Sbjct: 532 MDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWT 591
Query: 1118 LAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWK 1162
+ N+E R +H +++ + H +TG+ D + +WK
Sbjct: 592 IK---NNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILWK 633
Score = 53.2 bits (122), Expect = 7e-06
Identities = 60/289 (20%), Positives = 116/289 (40%), Gaps = 22/289 (7%)
Query: 992 VWQLSTHRLQATLNGHIGHITCVTF-SPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
+++ + RLQ G+ + V F P + V+ S + V++L ++ + + GH+
Sbjct: 318 LYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQTSACQILH-GHT 376
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVD-SGIVLHSATGPSASIDV------TLNMKY 1103
+ L + G S + ++V +W ++ +G V+ A G + V L +
Sbjct: 377 DIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESF 436
Query: 1104 AVLSDGDNSVRIW----SLAGGDNSEDNRRSV--------SHAERITCFALTADSQHVVT 1151
V D +V++W +L + + DN + H + I A+ + + + T
Sbjct: 437 LVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLAT 496
Query: 1152 GSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXX 1211
GS D + K+W L +L V GH + CV S ++ + + S D + +W +
Sbjct: 497 GSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQV-LATASADGTIKLWALQDFSC 555
Query: 1212 XXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
V V GT +S D + +W K + + H
Sbjct: 556 LKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAH 604
Score = 53.2 bits (122), Expect = 7e-06
Identities = 51/215 (23%), Positives = 85/215 (39%), Gaps = 19/215 (8%)
Query: 692 GHSGSILCMCVTR-ESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVL--------C- 741
GH+ S+ +C +R + +L+TGS+D +V +W L + P+L C
Sbjct: 419 GHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCH 478
Query: 742 ------VAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFIT 795
VA N L+ +G D + +L L+ HR + V+ + T
Sbjct: 479 DKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLAT 538
Query: 796 GSQDGTVCTWNVENFTLLSTVTAGVPIHIFDV--TDDNVFLLTLQGDNELHLRTFITGTY 853
S DGT+ W +++F+ L T G + V LL+ D + L T
Sbjct: 539 ASADGTIKLWALQDFSCLKTF-EGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNEC 597
Query: 854 LHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
+ L H+ KV + G +D R+ L+
Sbjct: 598 VRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILW 632
Score = 52.4 bits (120), Expect = 1e-05
Identities = 59/254 (23%), Positives = 97/254 (38%), Gaps = 19/254 (7%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKG-HSGSILCMCVTRESQYLLTGSEDTSV 718
L+P + LV A A W S K H+ + M S L TG D +V
Sbjct: 74 LSPDNEVLVTASRALLLAQWAWQEGSVTRLSKAIHTAPVATMAFDPTSTLLATGGCDGAV 133
Query: 719 IVWDL--HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
VWD+ H + + ++ R L+ S D+A+ + SL D + + L
Sbjct: 134 RVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTA 193
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN------FTLLSTVTAGV-----PIHIF 825
H +VTS+ DG+ ++ +D W++++ + +V A V P+
Sbjct: 194 HYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPVSQL 253
Query: 826 DVTDDNVFLLTLQGDNELHLRTFITG----TYLHPLKRHKAKVKCFCVAHDSSRVAVGCA 881
V ++ LT L + +G T P + C +AH + V A
Sbjct: 254 GVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGQELTHC-TLAHTAGVVLTATA 312
Query: 882 DQRIYLYSLHSAQL 895
D + LY S +L
Sbjct: 313 DHNLLLYEARSLRL 326
Score = 46.0 bits (104), Expect = 0.001
Identities = 28/130 (21%), Positives = 53/130 (40%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T + H I + + + L TGS+D + +W L + H + CV
Sbjct: 474 TQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMD 533
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
++ + D + + +L D + + + H SV V + G ++ DG V W ++
Sbjct: 534 QVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIK 593
Query: 809 NFTLLSTVTA 818
N + T+ A
Sbjct: 594 NNECVRTLDA 603
Score = 41.5 bits (93), Expect = 0.021
Identities = 25/107 (23%), Positives = 41/107 (38%)
Query: 971 CLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDR 1030
C++ S Q+ A+ A G +++W L T GH + V F +LS D
Sbjct: 526 CVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDG 585
Query: 1031 TVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
V +W + +N T H + L A++ V +W
Sbjct: 586 LVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILW 632
Score = 41.5 bits (93), Expect = 0.021
Identities = 27/105 (25%), Positives = 44/105 (41%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+Q +P Q L A + G +LW + S + TF+GH S+L + LL+ D
Sbjct: 527 VQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGL 586
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVII 762
V +W + + H V + ++G DS VI+
Sbjct: 587 VKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVIL 631
Score = 41.1 bits (92), Expect = 0.028
Identities = 53/260 (20%), Positives = 107/260 (41%), Gaps = 30/260 (11%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTH---RLQATLNGH---IGHITCVTFSPNNLL 1022
+ L+V R G L AS VR+W+++ A +GH +G + C +
Sbjct: 379 VLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKES--F 436
Query: 1023 VLSGSEDRTVVVWQL----------ADNSPSL-----TYKGHSSAIQTLLMMSDGRRAMS 1067
+++GS+D TV +W L DN P L T + H I ++ + + + +
Sbjct: 437 LVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLAT 496
Query: 1068 SDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVL--SDGDNSVRIWSLAGGDNS 1124
+ R +W + +L +G + V + VL + D ++++W+L +
Sbjct: 497 GSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWAL---QDF 553
Query: 1125 EDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAV 1184
+ H + A + +++ D +K+W + + + L H D V +
Sbjct: 554 SCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHC 613
Query: 1185 SITNKTQVVSGSWDCNLIVW 1204
S + ++G+ D +I+W
Sbjct: 614 SRLD-DHALTGASDSRVILW 632
Score = 40.7 bits (91), Expect = 0.038
Identities = 40/178 (22%), Positives = 65/178 (36%), Gaps = 5/178 (2%)
Query: 1074 VHVWLVDSGIVLHSATGPSASIDVT---LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
V++ V SG VL S D+T L+ VL ++ + A + S
Sbjct: 47 VNILEVASGAVLRSLEQEDQE-DITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLSK 105
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSIT-NK 1189
H + A S + TG D +++VW + + G +V VA +
Sbjct: 106 AIHTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTR 165
Query: 1190 TQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+ S + D + VW + VT + + DG +S DK IIW+
Sbjct: 166 LLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWD 223
Score = 37.1 bits (82), Expect = 0.46
Identities = 39/169 (23%), Positives = 67/169 (39%), Gaps = 10/169 (5%)
Query: 958 LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVW---QLSTHRLQATLNGHIGHITCV 1014
L EQ D I+ ++S D ++ + L+ W + S RL + H + +
Sbjct: 58 LRSLEQEDQEDITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLSKAI--HTAPVATM 115
Query: 1015 TFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAM--SSDRAR 1072
F P + L+ +G D V VW + + + ++G + + D R + SS
Sbjct: 116 AFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDA 175
Query: 1073 NVHVW-LVDSGIVLHSATGPSASIDVTLNMK-YAVLSDG-DNSVRIWSL 1118
+ VW L D + SA + + + +LS G D IW L
Sbjct: 176 AIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDL 224
>BC014007-1|AAH14007.1| 808|Homo sapiens TBL3 protein protein.
Length = 808
Score = 77.0 bits (181), Expect = 5e-13
Identities = 69/300 (23%), Positives = 121/300 (40%), Gaps = 20/300 (6%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPN--NLLVLS 1025
P++ + L A+G G VRVW + H G G + V F P+ LL+ S
Sbjct: 111 PVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFS 170
Query: 1026 GSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW-------- 1077
+ D + VW L D S H SA+ +L +DG +SS R + +W
Sbjct: 171 SATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQAT 230
Query: 1078 -------LVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
V++ ++L P + + V Y + + ++R+W A G +
Sbjct: 231 RTVPVFESVEAAVLLPEE--PVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQP 288
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKT 1190
+ +T L + V+T + D +L +++ +L + G+S+ V V +
Sbjct: 289 PGPGQELTHCTLAHTAGVVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDS 348
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
VV S L V+++ T V + V G + SCA+D+++ IW +
Sbjct: 349 HVVVASNSPCLKVFELQTSACQILHGHTDI-VLALDVFRKGWLFASCAKDQSVRIWRMNK 407
Score = 61.7 bits (143), Expect = 2e-08
Identities = 36/140 (25%), Positives = 69/140 (49%), Gaps = 3/140 (2%)
Query: 943 KQMKRRQTKSTTNITLLQAEQSDLI---PISCLEVSRDGQLGASGCARGLVRVWQLSTHR 999
K + + T LLQA+ + I+ + ++ + +L A+G ++W L +
Sbjct: 453 KALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQ 512
Query: 1000 LQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
L +GH + CV FSP + ++ + S D T+ +W L D S T++GH +++ + +
Sbjct: 513 LLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFV 572
Query: 1060 SDGRRAMSSDRARNVHVWLV 1079
S G + +SS V +W +
Sbjct: 573 SRGTQLLSSGSDGLVKLWTI 592
Score = 58.4 bits (135), Expect = 2e-07
Identities = 36/146 (24%), Positives = 62/146 (42%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
+AP+ + L +LW + + F GH + C+ + Q L T S D ++
Sbjct: 487 IAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIK 546
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
+W L + H A VL VA + + ++S G D V + ++ + V LD H
Sbjct: 547 LWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHED 606
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTW 805
V + + + +TG+ D V W
Sbjct: 607 KVWGLHCSRLDDHALTGASDSRVILW 632
Score = 53.6 bits (123), Expect = 5e-06
Identities = 59/254 (23%), Positives = 98/254 (38%), Gaps = 19/254 (7%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKG-HSGSILCMCVTRESQYLLTGSEDTSV 718
L+P + LV A A W S +K H+ + M S L TG D +V
Sbjct: 74 LSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGCDGAV 133
Query: 719 IVWDL--HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
VWD+ H + + ++ R L+ S D+A+ + SL D + + L
Sbjct: 134 RVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTA 193
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN------FTLLSTVTAGV-----PIHIF 825
H +VTS+ DG+ ++ +D W++++ + +V A V P+
Sbjct: 194 HYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPVSQL 253
Query: 826 DVTDDNVFLLTLQGDNELHLRTFITG----TYLHPLKRHKAKVKCFCVAHDSSRVAVGCA 881
V ++ LT L + +G T P + C +AH + V A
Sbjct: 254 GVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGQELTHC-TLAHTAGVVLTATA 312
Query: 882 DQRIYLYSLHSAQL 895
D + LY S +L
Sbjct: 313 DHNLLLYEARSLRL 326
Score = 53.6 bits (123), Expect = 5e-06
Identities = 38/165 (23%), Positives = 72/165 (43%), Gaps = 6/165 (3%)
Query: 1001 QATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMS 1060
Q T H I V +PN+ L+ +GS+DRT +W L + GH + +
Sbjct: 472 QTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSP 531
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI--DVTLNMKYAVLSDG-DNSVRIWS 1117
+ ++ + +W + L + G AS+ ++ +LS G D V++W+
Sbjct: 532 MDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWT 591
Query: 1118 LAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWK 1162
+ N+E R +H +++ + H +TG+ D + +WK
Sbjct: 592 IK---NNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILWK 633
Score = 53.2 bits (122), Expect = 7e-06
Identities = 60/289 (20%), Positives = 116/289 (40%), Gaps = 22/289 (7%)
Query: 992 VWQLSTHRLQATLNGHIGHITCVTF-SPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
+++ + RLQ G+ + V F P + V+ S + V++L ++ + + GH+
Sbjct: 318 LYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQTSACQILH-GHT 376
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVD-SGIVLHSATGPSASIDV------TLNMKY 1103
+ L + G S + ++V +W ++ +G V+ A G + V L +
Sbjct: 377 DIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESF 436
Query: 1104 AVLSDGDNSVRIW----SLAGGDNSEDNRRSV--------SHAERITCFALTADSQHVVT 1151
V D +V++W +L + + DN + H + I A+ + + + T
Sbjct: 437 LVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLAT 496
Query: 1152 GSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXX 1211
GS D + K+W L +L V GH + CV S ++ + + S D + +W +
Sbjct: 497 GSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQV-LATASADGTIKLWALQDFSC 555
Query: 1212 XXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
V V GT +S D + +W K + + H
Sbjct: 556 LKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAH 604
Score = 53.2 bits (122), Expect = 7e-06
Identities = 51/215 (23%), Positives = 85/215 (39%), Gaps = 19/215 (8%)
Query: 692 GHSGSILCMCVTR-ESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVL--------C- 741
GH+ S+ +C +R + +L+TGS+D +V +W L + P+L C
Sbjct: 419 GHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCH 478
Query: 742 ------VAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFIT 795
VA N L+ +G D + +L L+ HR + V+ + T
Sbjct: 479 DKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLAT 538
Query: 796 GSQDGTVCTWNVENFTLLSTVTAGVPIHIFDV--TDDNVFLLTLQGDNELHLRTFITGTY 853
S DGT+ W +++F+ L T G + V LL+ D + L T
Sbjct: 539 ASADGTIKLWALQDFSCLKTF-EGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNEC 597
Query: 854 LHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
+ L H+ KV + G +D R+ L+
Sbjct: 598 VRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILW 632
Score = 46.0 bits (104), Expect = 0.001
Identities = 28/130 (21%), Positives = 53/130 (40%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T + H I + + + L TGS+D + +W L + H + CV
Sbjct: 474 TQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMD 533
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
++ + D + + +L D + + + H SV V + G ++ DG V W ++
Sbjct: 534 QVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIK 593
Query: 809 NFTLLSTVTA 818
N + T+ A
Sbjct: 594 NNECVRTLDA 603
Score = 41.5 bits (93), Expect = 0.021
Identities = 25/107 (23%), Positives = 41/107 (38%)
Query: 971 CLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDR 1030
C++ S Q+ A+ A G +++W L T GH + V F +LS D
Sbjct: 526 CVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDG 585
Query: 1031 TVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
V +W + +N T H + L A++ V +W
Sbjct: 586 LVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILW 632
Score = 41.5 bits (93), Expect = 0.021
Identities = 27/105 (25%), Positives = 44/105 (41%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+Q +P Q L A + G +LW + S + TF+GH S+L + LL+ D
Sbjct: 527 VQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGL 586
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVII 762
V +W + + H V + ++G DS VI+
Sbjct: 587 VKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVIL 631
Score = 41.1 bits (92), Expect = 0.028
Identities = 53/260 (20%), Positives = 107/260 (41%), Gaps = 30/260 (11%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTH---RLQATLNGH---IGHITCVTFSPNNLL 1022
+ L+V R G L AS VR+W+++ A +GH +G + C +
Sbjct: 379 VLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKES--F 436
Query: 1023 VLSGSEDRTVVVWQL----------ADNSPSL-----TYKGHSSAIQTLLMMSDGRRAMS 1067
+++GS+D TV +W L DN P L T + H I ++ + + + +
Sbjct: 437 LVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLAT 496
Query: 1068 SDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVL--SDGDNSVRIWSLAGGDNS 1124
+ R +W + +L +G + V + VL + D ++++W+L +
Sbjct: 497 GSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWAL---QDF 553
Query: 1125 EDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAV 1184
+ H + A + +++ D +K+W + + + L H D V +
Sbjct: 554 SCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHC 613
Query: 1185 SITNKTQVVSGSWDCNLIVW 1204
S + ++G+ D +I+W
Sbjct: 614 SRLD-DHALTGASDSRVILW 632
Score = 39.9 bits (89), Expect = 0.066
Identities = 40/178 (22%), Positives = 65/178 (36%), Gaps = 5/178 (2%)
Query: 1074 VHVWLVDSGIVLHSATGPSASIDVT---LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
V++ V SG VL S D+T L+ VL ++ + A + S
Sbjct: 47 VNILEVASGAVLRSLEQEDQE-DITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWK 105
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSIT-NK 1189
H + A S + TG D +++VW + + G +V VA +
Sbjct: 106 AIHTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTR 165
Query: 1190 TQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+ S + D + VW + VT + + DG +S DK IIW+
Sbjct: 166 LLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWD 223
Score = 36.3 bits (80), Expect = 0.81
Identities = 39/169 (23%), Positives = 67/169 (39%), Gaps = 10/169 (5%)
Query: 958 LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVW---QLSTHRLQATLNGHIGHITCV 1014
L EQ D I+ ++S D ++ + L+ W + S RL + H + +
Sbjct: 58 LRSLEQEDQEDITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAI--HTAPVATM 115
Query: 1015 TFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAM--SSDRAR 1072
F P + L+ +G D V VW + + + ++G + + D R + SS
Sbjct: 116 AFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDA 175
Query: 1073 NVHVW-LVDSGIVLHSATGPSASIDVTLNMK-YAVLSDG-DNSVRIWSL 1118
+ VW L D + SA + + + +LS G D IW L
Sbjct: 176 AIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDL 224
>BC010231-1|AAH10231.1| 808|Homo sapiens transducin (beta)-like 3
protein.
Length = 808
Score = 77.0 bits (181), Expect = 5e-13
Identities = 69/300 (23%), Positives = 121/300 (40%), Gaps = 20/300 (6%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPN--NLLVLS 1025
P++ + L A+G G VRVW + H G G + V F P+ LL+ S
Sbjct: 111 PVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFS 170
Query: 1026 GSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW-------- 1077
+ D + VW L D S H SA+ +L +DG +SS R + +W
Sbjct: 171 SATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQAT 230
Query: 1078 -------LVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
V++ ++L P + + V Y + + ++R+W A G +
Sbjct: 231 RTVPVFESVEAAVLLPEE--PVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQP 288
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKT 1190
+ +T L + V+T + D +L +++ +L + G+S+ V V +
Sbjct: 289 PGPGQELTHCTLAHTAGVVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDS 348
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
VV S L V+++ T V + V G + SCA+D+++ IW +
Sbjct: 349 HVVVASNSPCLKVFELQTSACQILHGHTDI-VLALDVFRKGWLFASCAKDQSVRIWRMNK 407
Score = 61.7 bits (143), Expect = 2e-08
Identities = 36/140 (25%), Positives = 69/140 (49%), Gaps = 3/140 (2%)
Query: 943 KQMKRRQTKSTTNITLLQAEQSDLI---PISCLEVSRDGQLGASGCARGLVRVWQLSTHR 999
K + + T LLQA+ + I+ + ++ + +L A+G ++W L +
Sbjct: 453 KALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQ 512
Query: 1000 LQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
L +GH + CV FSP + ++ + S D T+ +W L D S T++GH +++ + +
Sbjct: 513 LLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFV 572
Query: 1060 SDGRRAMSSDRARNVHVWLV 1079
S G + +SS V +W +
Sbjct: 573 SRGTQLLSSGSDGLVKLWTI 592
Score = 58.4 bits (135), Expect = 2e-07
Identities = 36/146 (24%), Positives = 62/146 (42%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
+AP+ + L +LW + + F GH + C+ + Q L T S D ++
Sbjct: 487 IAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIK 546
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
+W L + H A VL VA + + ++S G D V + ++ + V LD H
Sbjct: 547 LWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHED 606
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTW 805
V + + + +TG+ D V W
Sbjct: 607 KVWGLHCSRLDDHALTGASDSRVILW 632
Score = 53.6 bits (123), Expect = 5e-06
Identities = 59/254 (23%), Positives = 98/254 (38%), Gaps = 19/254 (7%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKG-HSGSILCMCVTRESQYLLTGSEDTSV 718
L+P + LV A A W S +K H+ + M S L TG D +V
Sbjct: 74 LSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGCDGAV 133
Query: 719 IVWDL--HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
VWD+ H + + ++ R L+ S D+A+ + SL D + + L
Sbjct: 134 RVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTA 193
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN------FTLLSTVTAGV-----PIHIF 825
H +VTS+ DG+ ++ +D W++++ + +V A V P+
Sbjct: 194 HYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPVSQL 253
Query: 826 DVTDDNVFLLTLQGDNELHLRTFITG----TYLHPLKRHKAKVKCFCVAHDSSRVAVGCA 881
V ++ LT L + +G T P + C +AH + V A
Sbjct: 254 GVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGQELTHC-TLAHTAGVVLTATA 312
Query: 882 DQRIYLYSLHSAQL 895
D + LY S +L
Sbjct: 313 DHNLLLYEARSLRL 326
Score = 53.6 bits (123), Expect = 5e-06
Identities = 38/165 (23%), Positives = 72/165 (43%), Gaps = 6/165 (3%)
Query: 1001 QATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMS 1060
Q T H I V +PN+ L+ +GS+DRT +W L + GH + +
Sbjct: 472 QTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSP 531
Query: 1061 DGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI--DVTLNMKYAVLSDG-DNSVRIWS 1117
+ ++ + +W + L + G AS+ ++ +LS G D V++W+
Sbjct: 532 MDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWT 591
Query: 1118 LAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWK 1162
+ N+E R +H +++ + H +TG+ D + +WK
Sbjct: 592 IK---NNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILWK 633
Score = 53.2 bits (122), Expect = 7e-06
Identities = 60/289 (20%), Positives = 116/289 (40%), Gaps = 22/289 (7%)
Query: 992 VWQLSTHRLQATLNGHIGHITCVTF-SPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
+++ + RLQ G+ + V F P + V+ S + V++L ++ + + GH+
Sbjct: 318 LYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQTSACQILH-GHT 376
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVD-SGIVLHSATGPSASIDV------TLNMKY 1103
+ L + G S + ++V +W ++ +G V+ A G + V L +
Sbjct: 377 DIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESF 436
Query: 1104 AVLSDGDNSVRIW----SLAGGDNSEDNRRSV--------SHAERITCFALTADSQHVVT 1151
V D +V++W +L + + DN + H + I A+ + + + T
Sbjct: 437 LVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLAT 496
Query: 1152 GSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXX 1211
GS D + K+W L +L V GH + CV S ++ + + S D + +W +
Sbjct: 497 GSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQV-LATASADGTIKLWALQDFSC 555
Query: 1212 XXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
V V GT +S D + +W K + + H
Sbjct: 556 LKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAH 604
Score = 53.2 bits (122), Expect = 7e-06
Identities = 51/215 (23%), Positives = 85/215 (39%), Gaps = 19/215 (8%)
Query: 692 GHSGSILCMCVTR-ESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVL--------C- 741
GH+ S+ +C +R + +L+TGS+D +V +W L + P+L C
Sbjct: 419 GHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCH 478
Query: 742 ------VAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFIT 795
VA N L+ +G D + +L L+ HR + V+ + T
Sbjct: 479 DKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLAT 538
Query: 796 GSQDGTVCTWNVENFTLLSTVTAGVPIHIFDV--TDDNVFLLTLQGDNELHLRTFITGTY 853
S DGT+ W +++F+ L T G + V LL+ D + L T
Sbjct: 539 ASADGTIKLWALQDFSCLKTF-EGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNEC 597
Query: 854 LHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
+ L H+ KV + G +D R+ L+
Sbjct: 598 VRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILW 632
Score = 46.0 bits (104), Expect = 0.001
Identities = 28/130 (21%), Positives = 53/130 (40%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T + H I + + + L TGS+D + +W L + H + CV
Sbjct: 474 TQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMD 533
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
++ + D + + +L D + + + H SV V + G ++ DG V W ++
Sbjct: 534 QVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIK 593
Query: 809 NFTLLSTVTA 818
N + T+ A
Sbjct: 594 NNECVRTLDA 603
Score = 41.5 bits (93), Expect = 0.021
Identities = 25/107 (23%), Positives = 41/107 (38%)
Query: 971 CLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDR 1030
C++ S Q+ A+ A G +++W L T GH + V F +LS D
Sbjct: 526 CVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDG 585
Query: 1031 TVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
V +W + +N T H + L A++ V +W
Sbjct: 586 LVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILW 632
Score = 41.5 bits (93), Expect = 0.021
Identities = 27/105 (25%), Positives = 44/105 (41%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+Q +P Q L A + G +LW + S + TF+GH S+L + LL+ D
Sbjct: 527 VQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGL 586
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVII 762
V +W + + H V + ++G DS VI+
Sbjct: 587 VKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVIL 631
Score = 41.1 bits (92), Expect = 0.028
Identities = 53/260 (20%), Positives = 107/260 (41%), Gaps = 30/260 (11%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTH---RLQATLNGH---IGHITCVTFSPNNLL 1022
+ L+V R G L AS VR+W+++ A +GH +G + C +
Sbjct: 379 VLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKES--F 436
Query: 1023 VLSGSEDRTVVVWQL----------ADNSPSL-----TYKGHSSAIQTLLMMSDGRRAMS 1067
+++GS+D TV +W L DN P L T + H I ++ + + + +
Sbjct: 437 LVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLAT 496
Query: 1068 SDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVL--SDGDNSVRIWSLAGGDNS 1124
+ R +W + +L +G + V + VL + D ++++W+L +
Sbjct: 497 GSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWAL---QDF 553
Query: 1125 EDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAV 1184
+ H + A + +++ D +K+W + + + L H D V +
Sbjct: 554 SCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHC 613
Query: 1185 SITNKTQVVSGSWDCNLIVW 1204
S + ++G+ D +I+W
Sbjct: 614 SRLD-DHALTGASDSRVILW 632
Score = 39.9 bits (89), Expect = 0.066
Identities = 40/178 (22%), Positives = 65/178 (36%), Gaps = 5/178 (2%)
Query: 1074 VHVWLVDSGIVLHSATGPSASIDVT---LNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
V++ V SG VL S D+T L+ VL ++ + A + S
Sbjct: 47 VNILEVASGAVLRSLEQEDQE-DITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWK 105
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSIT-NK 1189
H + A S + TG D +++VW + + G +V VA +
Sbjct: 106 AIHTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTR 165
Query: 1190 TQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+ S + D + VW + VT + + DG +S DK IIW+
Sbjct: 166 LLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWD 223
Score = 36.3 bits (80), Expect = 0.81
Identities = 39/169 (23%), Positives = 67/169 (39%), Gaps = 10/169 (5%)
Query: 958 LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVW---QLSTHRLQATLNGHIGHITCV 1014
L EQ D I+ ++S D ++ + L+ W + S RL + H + +
Sbjct: 58 LRSLEQEDQEDITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAI--HTAPVATM 115
Query: 1015 TFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAM--SSDRAR 1072
F P + L+ +G D V VW + + + ++G + + D R + SS
Sbjct: 116 AFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDA 175
Query: 1073 NVHVW-LVDSGIVLHSATGPSASIDVTLNMK-YAVLSDG-DNSVRIWSL 1118
+ VW L D + SA + + + +LS G D IW L
Sbjct: 176 AIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDL 224
>AJ243008-1|CAB55584.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 77.0 bits (181), Expect = 5e-13
Identities = 96/460 (20%), Positives = 177/460 (38%), Gaps = 37/460 (8%)
Query: 828 TDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRV--AVGCADQRI 885
TDD F+ T D ++ + +TG +H H +V C + S + A G +D +
Sbjct: 667 TDDR-FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFL 725
Query: 886 YLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQM 945
L+ L+ + T LLA S + L + T
Sbjct: 726 KLWDLNQKECRNTMFGRTNSVNHCRFSPDDKLLA---------SCSADGTLKLWDATSAN 776
Query: 946 KRRQTKSTTNITLLQAEQSDL-IPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATL 1004
+R+ L+ Q D+ + + C S DG A+ + +W + A
Sbjct: 777 ERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGAR-IMVAAKNKIFLWNTDSRSKVADC 835
Query: 1005 NGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQ---LADNSPSLTYKGHSSAIQTLLMMSD 1061
GH+ + V FSP+ L+ S+D+T+ +W+ + NS + + Q +M
Sbjct: 836 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVM-- 893
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGG 1121
++ D R + + +G + + + ++ +++Y D + ++ I L
Sbjct: 894 ---VLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELV-- 948
Query: 1122 DNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTC 1181
N+ + H + + TAD + +++ S D ++VW K L GH + T
Sbjct: 949 -NNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCI-FLRGHQE--TV 1004
Query: 1182 VAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDK 1241
+ ++++S S+D + VW+I T V ++ D T S + DK
Sbjct: 1005 KDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADK 1064
Query: 1242 TLIIWETKRGLALTSFSLHVPLLGFQITSDCARVVVHLLD 1281
T IW SF L +PL + + C R +D
Sbjct: 1065 TAKIW---------SFDLLLPLHELRGHNGCVRCSAFSVD 1095
Score = 63.7 bits (148), Expect = 5e-09
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 1/147 (0%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKT 1190
+H + + C A + D + + T S+D +K+W G+L HS+ V C + ++
Sbjct: 655 AHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHL 714
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
+ +GS DC L +WD+N V + + D + SC+ D TL +W+
Sbjct: 715 LLATGSSDCFLKLWDLNQKECRNTMFGRTNSVNHCRFSPDDKLLASCSADGTLKLWDATS 774
Query: 1251 GLALTSFSLHVPLLGFQITSDCARVVV 1277
S ++ L + + V+V
Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIV 801
Score = 53.6 bits (123), Expect = 5e-06
Identities = 42/202 (20%), Positives = 91/202 (45%), Gaps = 5/202 (2%)
Query: 697 ILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGD 756
+ C C++ QY+ G E+ ++ + +L + +H V + + +IS D
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 757 DSAVIITSL-VDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLST 815
D+ + + + +D + L H+ +V +++++ + ++ S DGTV WN+
Sbjct: 981 DAEIQVWNWQLDKCIF--LRGHQETVKDFRLLKNSRL-LSWSFDGTVKVWNIITGNKEKD 1037
Query: 816 -VTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSS 874
V + D++ D + D + +F LH L+ H V+C + DS+
Sbjct: 1038 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST 1097
Query: 875 RVAVGCADQRIYLYSLHSAQLL 896
+A G + I ++++ + +LL
Sbjct: 1098 LLATGDDNGEIRIWNVSNGELL 1119
Score = 52.0 bits (119), Expect = 2e-05
Identities = 44/205 (21%), Positives = 86/205 (41%), Gaps = 12/205 (5%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC +S Q A G G + + +L +R+ + H + + F+ + ++S S+
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSG-----I 1083
D + VW + + +GH ++ ++ + R +S V VW + +G
Sbjct: 981 DAEIQVWNWQLDK-CIFLRGHQETVKDFRLLKNSR-LLSWSFDGTVKVWNIITGNKEKDF 1038
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
V H T S D++ + + D + +IWS D H + C A +
Sbjct: 1039 VCHQGT--VLSCDISHDATKFSSTSADKTAKIWSF---DLLLPLHELRGHNGCVRCSAFS 1093
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKL 1168
DS + TG + +++W + G+L
Sbjct: 1094 VDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 49.6 bits (113), Expect = 8e-05
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 10/142 (7%)
Query: 674 GDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKIL 733
G ++W+I++ +K F H G++L ++ ++ + S D + +W L ++
Sbjct: 1022 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1081
Query: 734 EHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALV---TKLDH-----HRGSVTSVK 785
H V C A V+ +L+ +G D+ + I ++ +G L+ L H G VT +
Sbjct: 1082 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1141
Query: 786 VIQDGNIFITGSQDGTVCTWNV 807
DG + I S G + WNV
Sbjct: 1142 FSPDGKMLI--SAGGYIKWWNV 1161
Score = 42.7 bits (96), Expect = 0.009
Identities = 49/272 (18%), Positives = 105/272 (38%), Gaps = 23/272 (8%)
Query: 997 THRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTL 1056
T+ + + H + FS + + S D+T+ V++ L K H +
Sbjct: 604 TNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCC 663
Query: 1057 LMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID---VTLNMKYAVLSDG--DN 1111
+D R + + V +W +G ++H+ S ++ T + + +L+ G D
Sbjct: 664 AFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDC 723
Query: 1112 SVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGG----- 1166
+++W L + E + + D + + + S D +LK+W
Sbjct: 724 FLKLWDL---NQKECRNTMFGRTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKS 780
Query: 1167 -KLSQVLVGHSD-------IVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXX 1218
+ Q + D IV C + S +V+ + +W+ ++
Sbjct: 781 INVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAK--NKIFLWNTDSRSKVADCRGH 838
Query: 1219 XXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
V V + DG+ ++ ++D+T+ +WETK+
Sbjct: 839 LSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK 870
Score = 42.3 bits (95), Expect = 0.012
Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 9/147 (6%)
Query: 988 GLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYK 1047
G V+VW + T + H G + S + S S D+T +W P +
Sbjct: 1022 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1081
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH---------SATGPSASIDVT 1098
GH+ ++ D + D + +W V +G +LH +AT D+
Sbjct: 1082 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1141
Query: 1099 LNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+ +L ++ W++ G++S+
Sbjct: 1142 FSPDGKMLISAGGYIKWWNVVTGESSQ 1168
Score = 41.1 bits (92), Expect = 0.028
Identities = 40/199 (20%), Positives = 79/199 (39%), Gaps = 7/199 (3%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
L+P Q++ G ++ +++N + H ++ + T + + L++ S+D +
Sbjct: 926 LSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQ 985
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
VW+ K L + ++ S ++S D V + +++ G H+G
Sbjct: 986 VWNWQ--LDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1043
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV---TAGVPIHIFDVTDDNVFLLT 836
+V S + D F + S D T W+ + L + V F V D+ L T
Sbjct: 1044 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSV--DSTLLAT 1101
Query: 837 LQGDNELHLRTFITGTYLH 855
+ E+ + G LH
Sbjct: 1102 GDDNGEIRIWNVSNGELLH 1120
Score = 40.7 bits (91), Expect = 0.038
Identities = 32/146 (21%), Positives = 57/146 (39%), Gaps = 4/146 (2%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
GQ + + Q++ + K+ K H +LC + + +++ T S D V +W+
Sbjct: 627 GQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNS 686
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRS---LVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
T + EH V C N S L+ +G D + + L + S
Sbjct: 687 MTGELVHTYDEHSEQVNC-CHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGRTNS 745
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWN 806
V + D + + S DGT+ W+
Sbjct: 746 VNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 40.3 bits (90), Expect = 0.050
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 3/104 (2%)
Query: 951 KSTTNIT-LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIG 1009
K+ TN++ L+ +D + +C S DGQ AS A ++V++ T + H
Sbjct: 601 KNITNLSRLVVRPHTDAVYHACF--SEDGQRIASCGADKTLQVFKAETGEKLLEIKAHED 658
Query: 1010 HITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
+ C FS ++ + + S D+ V +W TY HS +
Sbjct: 659 EVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQV 702
Score = 39.1 bits (87), Expect = 0.11
Identities = 29/129 (22%), Positives = 53/129 (41%), Gaps = 3/129 (2%)
Query: 951 KSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGH 1010
K+ T LL+ + + + C S D + A+ V++W T L T + H
Sbjct: 643 KAETGEKLLEIKAHE-DEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQ 701
Query: 1011 ITCVTF--SPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSS 1068
+ C F S ++LL+ +GS D + +W L T G ++++ D + S
Sbjct: 702 VNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGRTNSVNHCRFSPDDKLLASC 761
Query: 1069 DRARNVHVW 1077
+ +W
Sbjct: 762 SADGTLKLW 770
Score = 35.1 bits (77), Expect = 1.9
Identities = 26/117 (22%), Positives = 47/117 (40%), Gaps = 2/117 (1%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ ++ C + + Q + + D ++ V+ T +I H VLC A + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
+ D V I + + G LV D H V + + TGS D + W++
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
>AJ243007-1|CAB55583.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 77.0 bits (181), Expect = 5e-13
Identities = 96/460 (20%), Positives = 177/460 (38%), Gaps = 37/460 (8%)
Query: 828 TDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRV--AVGCADQRI 885
TDD F+ T D ++ + +TG +H H +V C + S + A G +D +
Sbjct: 667 TDDR-FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFL 725
Query: 886 YLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQM 945
L+ L+ + T LLA S + L + T
Sbjct: 726 KLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLA---------SCSADGTLKLWDATSAN 776
Query: 946 KRRQTKSTTNITLLQAEQSDL-IPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATL 1004
+R+ L+ Q D+ + + C S DG A+ + +W + A
Sbjct: 777 ERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGAR-IMVAAKNKIFLWNTDSRSKVADC 835
Query: 1005 NGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQ---LADNSPSLTYKGHSSAIQTLLMMSD 1061
GH+ + V FSP+ L+ S+D+T+ +W+ + NS + + Q +M
Sbjct: 836 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVM-- 893
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGG 1121
++ D R + + +G + + + ++ +++Y D + ++ I L
Sbjct: 894 ---VLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELV-- 948
Query: 1122 DNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTC 1181
N+ + H + + TAD + +++ S D ++VW K L GH + T
Sbjct: 949 -NNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCI-FLRGHQE--TV 1004
Query: 1182 VAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDK 1241
+ ++++S S+D + VW+I T V ++ D T S + DK
Sbjct: 1005 KDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADK 1064
Query: 1242 TLIIWETKRGLALTSFSLHVPLLGFQITSDCARVVVHLLD 1281
T IW SF L +PL + + C R +D
Sbjct: 1065 TAKIW---------SFDLLLPLHELRGHNGCVRCSAFSVD 1095
Score = 63.7 bits (148), Expect = 5e-09
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 1/147 (0%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKT 1190
+H + + C A + D + + T S+D +K+W G+L HS+ V C + ++
Sbjct: 655 AHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHL 714
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
+ +GS DC L +WD+N V + + D + SC+ D TL +W+
Sbjct: 715 LLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATS 774
Query: 1251 GLALTSFSLHVPLLGFQITSDCARVVV 1277
S ++ L + + V+V
Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIV 801
Score = 53.6 bits (123), Expect = 5e-06
Identities = 42/202 (20%), Positives = 91/202 (45%), Gaps = 5/202 (2%)
Query: 697 ILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGD 756
+ C C++ QY+ G E+ ++ + +L + +H V + + +IS D
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 757 DSAVIITSL-VDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLST 815
D+ + + + +D + L H+ +V +++++ + ++ S DGTV WN+
Sbjct: 981 DAEIQVWNWQLDKCIF--LRGHQETVKDFRLLKNSRL-LSWSFDGTVKVWNIITGNKEKD 1037
Query: 816 -VTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSS 874
V + D++ D + D + +F LH L+ H V+C + DS+
Sbjct: 1038 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST 1097
Query: 875 RVAVGCADQRIYLYSLHSAQLL 896
+A G + I ++++ + +LL
Sbjct: 1098 LLATGDDNGEIRIWNVSNGELL 1119
Score = 52.0 bits (119), Expect = 2e-05
Identities = 44/205 (21%), Positives = 86/205 (41%), Gaps = 12/205 (5%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC +S Q A G G + + +L +R+ + H + + F+ + ++S S+
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSG-----I 1083
D + VW + + +GH ++ ++ + R +S V VW + +G
Sbjct: 981 DAEIQVWNWQLDK-CIFLRGHQETVKDFRLLKNSR-LLSWSFDGTVKVWNIITGNKEKDF 1038
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
V H T S D++ + + D + +IWS D H + C A +
Sbjct: 1039 VCHQGT--VLSCDISHDATKFSSTSADKTAKIWSF---DLLLPLHELRGHNGCVRCSAFS 1093
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKL 1168
DS + TG + +++W + G+L
Sbjct: 1094 VDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 49.6 bits (113), Expect = 8e-05
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 10/142 (7%)
Query: 674 GDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKIL 733
G ++W+I++ +K F H G++L ++ ++ + S D + +W L ++
Sbjct: 1022 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1081
Query: 734 EHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALV---TKLDH-----HRGSVTSVK 785
H V C A V+ +L+ +G D+ + I ++ +G L+ L H G VT +
Sbjct: 1082 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1141
Query: 786 VIQDGNIFITGSQDGTVCTWNV 807
DG + I S G + WNV
Sbjct: 1142 FSPDGKMLI--SAGGYIKWWNV 1161
Score = 45.2 bits (102), Expect = 0.002
Identities = 50/272 (18%), Positives = 105/272 (38%), Gaps = 23/272 (8%)
Query: 997 THRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTL 1056
T+ + + H + FS + + S D+T V++ L K H +
Sbjct: 604 TNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTFQVFKAETGEKLLEIKAHEDEVLCC 663
Query: 1057 LMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID---VTLNMKYAVLSDG--DN 1111
+D R + + V +W +G ++H+ S ++ T + + +L+ G D
Sbjct: 664 AFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDC 723
Query: 1112 SVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGG----- 1166
+++W L + E H + + D + + + S D +LK+W
Sbjct: 724 FLKLWDL---NQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKS 780
Query: 1167 -KLSQVLVGHSD-------IVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXX 1218
+ Q + D IV C + S +V+ + +W+ ++
Sbjct: 781 INVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAK--NKIFLWNTDSRSKVADCRGH 838
Query: 1219 XXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
V V + DG+ ++ ++D+T+ +WETK+
Sbjct: 839 LSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK 870
Score = 43.6 bits (98), Expect = 0.005
Identities = 33/146 (22%), Positives = 58/146 (39%), Gaps = 4/146 (2%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
GQ + + Q++ + K+ K H +LC + + +++ T S D V +W+
Sbjct: 627 GQRIASCGADKTFQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNS 686
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRS---LVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
T + EH V C N S L+ +G D + + L + H S
Sbjct: 687 MTGELVHTYDEHSEQVNC-CHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNS 745
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWN 806
V + D + + S DGT+ W+
Sbjct: 746 VNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 42.3 bits (95), Expect = 0.012
Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 9/147 (6%)
Query: 988 GLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYK 1047
G V+VW + T + H G + S + S S D+T +W P +
Sbjct: 1022 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1081
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH---------SATGPSASIDVT 1098
GH+ ++ D + D + +W V +G +LH +AT D+
Sbjct: 1082 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1141
Query: 1099 LNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+ +L ++ W++ G++S+
Sbjct: 1142 FSPDGKMLISAGGYIKWWNVVTGESSQ 1168
Score = 41.1 bits (92), Expect = 0.028
Identities = 40/199 (20%), Positives = 79/199 (39%), Gaps = 7/199 (3%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
L+P Q++ G ++ +++N + H ++ + T + + L++ S+D +
Sbjct: 926 LSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQ 985
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
VW+ K L + ++ S ++S D V + +++ G H+G
Sbjct: 986 VWNWQ--LDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1043
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV---TAGVPIHIFDVTDDNVFLLT 836
+V S + D F + S D T W+ + L + V F V D+ L T
Sbjct: 1044 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSV--DSTLLAT 1101
Query: 837 LQGDNELHLRTFITGTYLH 855
+ E+ + G LH
Sbjct: 1102 GDDNGEIRIWNVSNGELLH 1120
Score = 39.5 bits (88), Expect = 0.087
Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 3/104 (2%)
Query: 951 KSTTNIT-LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIG 1009
K+ TN++ L+ +D + +C S DGQ AS A +V++ T + H
Sbjct: 601 KNITNLSRLVVRPHTDAVYHACF--SEDGQRIASCGADKTFQVFKAETGEKLLEIKAHED 658
Query: 1010 HITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
+ C FS ++ + + S D+ V +W TY HS +
Sbjct: 659 EVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQV 702
Score = 37.5 bits (83), Expect = 0.35
Identities = 26/118 (22%), Positives = 49/118 (41%)
Query: 918 LAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRD 977
+ A + V +F T+D + + T + E S+ + S
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSH 712
Query: 978 GQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVW 1035
L A+G + +++W L+ + T+ GH + FSP++ L+ S S D T+ +W
Sbjct: 713 HLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 770
Score = 34.3 bits (75), Expect = 3.3
Identities = 26/117 (22%), Positives = 46/117 (39%), Gaps = 2/117 (1%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ ++ C + + Q + + D + V+ T +I H VLC A + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTFQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
+ D V I + + G LV D H V + + TGS D + W++
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
>AJ243004-1|CAB55580.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 77.0 bits (181), Expect = 5e-13
Identities = 96/460 (20%), Positives = 177/460 (38%), Gaps = 37/460 (8%)
Query: 828 TDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRV--AVGCADQRI 885
TDD F+ T D ++ + +TG +H H +V C + S + A G +D +
Sbjct: 667 TDDR-FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFL 725
Query: 886 YLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQM 945
L+ L+ + T LLA S + L + T
Sbjct: 726 KLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLA---------SCSADGTLKLWDATSAN 776
Query: 946 KRRQTKSTTNITLLQAEQSDL-IPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATL 1004
+R+ L+ Q D+ + + C S DG A+ + +W + A
Sbjct: 777 ERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGAR-IMVAAKNKIFLWNTDSRSKVADC 835
Query: 1005 NGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQ---LADNSPSLTYKGHSSAIQTLLMMSD 1061
GH+ + V FSP+ L+ S+D+T+ +W+ + NS + + Q +M
Sbjct: 836 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVM-- 893
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGG 1121
++ D R + + +G + + + ++ +++Y D + ++ I L
Sbjct: 894 ---VLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELV-- 948
Query: 1122 DNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTC 1181
N+ + H + + TAD + +++ S D ++VW K L GH + T
Sbjct: 949 -NNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCI-FLRGHQE--TV 1004
Query: 1182 VAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDK 1241
+ ++++S S+D + VW+I T V ++ D T S + DK
Sbjct: 1005 KDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADK 1064
Query: 1242 TLIIWETKRGLALTSFSLHVPLLGFQITSDCARVVVHLLD 1281
T IW SF L +PL + + C R +D
Sbjct: 1065 TAKIW---------SFDLLLPLHELRGHNGCVRCSAFSVD 1095
Score = 63.7 bits (148), Expect = 5e-09
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 1/147 (0%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKT 1190
+H + + C A + D + + T S+D +K+W G+L HS+ V C + ++
Sbjct: 655 AHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHL 714
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
+ +GS DC L +WD+N V + + D + SC+ D TL +W+
Sbjct: 715 LLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATS 774
Query: 1251 GLALTSFSLHVPLLGFQITSDCARVVV 1277
S ++ L + + V+V
Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIV 801
Score = 53.6 bits (123), Expect = 5e-06
Identities = 42/202 (20%), Positives = 91/202 (45%), Gaps = 5/202 (2%)
Query: 697 ILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGD 756
+ C C++ QY+ G E+ ++ + +L + +H V + + +IS D
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 757 DSAVIITSL-VDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLST 815
D+ + + + +D + L H+ +V +++++ + ++ S DGTV WN+
Sbjct: 981 DAEIQVWNWQLDKCIF--LRGHQETVKDFRLLKNSRL-LSWSFDGTVKVWNIITGNKEKD 1037
Query: 816 -VTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSS 874
V + D++ D + D + +F LH L+ H V+C + DS+
Sbjct: 1038 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST 1097
Query: 875 RVAVGCADQRIYLYSLHSAQLL 896
+A G + I ++++ + +LL
Sbjct: 1098 LLATGDDNGEIRIWNVSNGELL 1119
Score = 52.0 bits (119), Expect = 2e-05
Identities = 44/205 (21%), Positives = 86/205 (41%), Gaps = 12/205 (5%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC +S Q A G G + + +L +R+ + H + + F+ + ++S S+
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSG-----I 1083
D + VW + + +GH ++ ++ + R +S V VW + +G
Sbjct: 981 DAEIQVWNWQLDK-CIFLRGHQETVKDFRLLKNSR-LLSWSFDGTVKVWNIITGNKEKDF 1038
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
V H T S D++ + + D + +IWS D H + C A +
Sbjct: 1039 VCHQGT--VLSCDISHDATKFSSTSADKTAKIWSF---DLLLPLHELRGHNGCVRCSAFS 1093
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKL 1168
DS + TG + +++W + G+L
Sbjct: 1094 VDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 49.6 bits (113), Expect = 8e-05
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 10/142 (7%)
Query: 674 GDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKIL 733
G ++W+I++ +K F H G++L ++ ++ + S D + +W L ++
Sbjct: 1022 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1081
Query: 734 EHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALV---TKLDH-----HRGSVTSVK 785
H V C A V+ +L+ +G D+ + I ++ +G L+ L H G VT +
Sbjct: 1082 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1141
Query: 786 VIQDGNIFITGSQDGTVCTWNV 807
DG + I S G + WNV
Sbjct: 1142 FSPDGKMLI--SAGGYIKWWNV 1161
Score = 46.0 bits (104), Expect = 0.001
Identities = 50/272 (18%), Positives = 106/272 (38%), Gaps = 23/272 (8%)
Query: 997 THRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTL 1056
T+ + + H + FS + + S D+T+ V++ L K H +
Sbjct: 604 TNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCC 663
Query: 1057 LMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID---VTLNMKYAVLSDG--DN 1111
+D R + + V +W +G ++H+ S ++ T + + +L+ G D
Sbjct: 664 AFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDC 723
Query: 1112 SVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGG----- 1166
+++W L + E H + + D + + + S D +LK+W
Sbjct: 724 FLKLWDL---NQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKS 780
Query: 1167 -KLSQVLVGHSD-------IVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXX 1218
+ Q + D IV C + S +V+ + +W+ ++
Sbjct: 781 INVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAK--NKIFLWNTDSRSKVADCRGH 838
Query: 1219 XXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
V V + DG+ ++ ++D+T+ +WETK+
Sbjct: 839 LSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK 870
Score = 44.0 bits (99), Expect = 0.004
Identities = 33/146 (22%), Positives = 58/146 (39%), Gaps = 4/146 (2%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
GQ + + Q++ + K+ K H +LC + + +++ T S D V +W+
Sbjct: 627 GQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNS 686
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRS---LVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
T + EH V C N S L+ +G D + + L + H S
Sbjct: 687 MTGELVHTYDEHSEQVNC-CHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNS 745
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWN 806
V + D + + S DGT+ W+
Sbjct: 746 VNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 42.3 bits (95), Expect = 0.012
Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 9/147 (6%)
Query: 988 GLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYK 1047
G V+VW + T + H G + S + S S D+T +W P +
Sbjct: 1022 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1081
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH---------SATGPSASIDVT 1098
GH+ ++ D + D + +W V +G +LH +AT D+
Sbjct: 1082 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1141
Query: 1099 LNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+ +L ++ W++ G++S+
Sbjct: 1142 FSPDGKMLISAGGYIKWWNVVTGESSQ 1168
Score = 41.1 bits (92), Expect = 0.028
Identities = 40/199 (20%), Positives = 79/199 (39%), Gaps = 7/199 (3%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
L+P Q++ G ++ +++N + H ++ + T + + L++ S+D +
Sbjct: 926 LSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQ 985
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
VW+ K L + ++ S ++S D V + +++ G H+G
Sbjct: 986 VWNWQ--LDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1043
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV---TAGVPIHIFDVTDDNVFLLT 836
+V S + D F + S D T W+ + L + V F V D+ L T
Sbjct: 1044 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSV--DSTLLAT 1101
Query: 837 LQGDNELHLRTFITGTYLH 855
+ E+ + G LH
Sbjct: 1102 GDDNGEIRIWNVSNGELLH 1120
Score = 40.3 bits (90), Expect = 0.050
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 3/104 (2%)
Query: 951 KSTTNIT-LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIG 1009
K+ TN++ L+ +D + +C S DGQ AS A ++V++ T + H
Sbjct: 601 KNITNLSRLVVRPHTDAVYHACF--SEDGQRIASCGADKTLQVFKAETGEKLLEIKAHED 658
Query: 1010 HITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
+ C FS ++ + + S D+ V +W TY HS +
Sbjct: 659 EVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQV 702
Score = 37.5 bits (83), Expect = 0.35
Identities = 26/118 (22%), Positives = 49/118 (41%)
Query: 918 LAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRD 977
+ A + V +F T+D + + T + E S+ + S
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSH 712
Query: 978 GQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVW 1035
L A+G + +++W L+ + T+ GH + FSP++ L+ S S D T+ +W
Sbjct: 713 HLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 770
Score = 35.1 bits (77), Expect = 1.9
Identities = 26/117 (22%), Positives = 47/117 (40%), Gaps = 2/117 (1%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ ++ C + + Q + + D ++ V+ T +I H VLC A + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
+ D V I + + G LV D H V + + TGS D + W++
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
>AF013263-1|AAC51678.1| 1194|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1194
Score = 77.0 bits (181), Expect = 5e-13
Identities = 96/460 (20%), Positives = 177/460 (38%), Gaps = 37/460 (8%)
Query: 828 TDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRV--AVGCADQRI 885
TDD F+ T D ++ + +TG +H H +V C + S + A G +D +
Sbjct: 656 TDDR-FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFL 714
Query: 886 YLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQM 945
L+ L+ + T LLA S + L + T
Sbjct: 715 KLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLA---------SCSADGTLKLWDATSAN 765
Query: 946 KRRQTKSTTNITLLQAEQSDL-IPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATL 1004
+R+ L+ Q D+ + + C S DG A+ + +W + A
Sbjct: 766 ERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGAR-IMVAAKNKIFLWNTDSRSKVADC 824
Query: 1005 NGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQ---LADNSPSLTYKGHSSAIQTLLMMSD 1061
GH+ + V FSP+ L+ S+D+T+ +W+ + NS + + Q +M
Sbjct: 825 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVM-- 882
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGG 1121
++ D R + + +G + + + ++ +++Y D + ++ I L
Sbjct: 883 ---VLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELV-- 937
Query: 1122 DNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTC 1181
N+ + H + + TAD + +++ S D ++VW K L GH + T
Sbjct: 938 -NNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCI-FLRGHQE--TV 993
Query: 1182 VAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDK 1241
+ ++++S S+D + VW+I T V ++ D T S + DK
Sbjct: 994 KDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADK 1053
Query: 1242 TLIIWETKRGLALTSFSLHVPLLGFQITSDCARVVVHLLD 1281
T IW SF L +PL + + C R +D
Sbjct: 1054 TAKIW---------SFDLLLPLHELRGHNGCVRCSAFSVD 1084
Score = 63.7 bits (148), Expect = 5e-09
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 1/147 (0%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKT 1190
+H + + C A + D + + T S+D +K+W G+L HS+ V C + ++
Sbjct: 644 AHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHL 703
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
+ +GS DC L +WD+N V + + D + SC+ D TL +W+
Sbjct: 704 LLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATS 763
Query: 1251 GLALTSFSLHVPLLGFQITSDCARVVV 1277
S ++ L + + V+V
Sbjct: 764 ANERKSINVKQFFLNLEDPQEDMEVIV 790
Score = 53.6 bits (123), Expect = 5e-06
Identities = 42/202 (20%), Positives = 91/202 (45%), Gaps = 5/202 (2%)
Query: 697 ILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGD 756
+ C C++ QY+ G E+ ++ + +L + +H V + + +IS D
Sbjct: 910 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 969
Query: 757 DSAVIITSL-VDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLST 815
D+ + + + +D + L H+ +V +++++ + ++ S DGTV WN+
Sbjct: 970 DAEIQVWNWQLDKCIF--LRGHQETVKDFRLLKNSRL-LSWSFDGTVKVWNIITGNKEKD 1026
Query: 816 -VTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSS 874
V + D++ D + D + +F LH L+ H V+C + DS+
Sbjct: 1027 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST 1086
Query: 875 RVAVGCADQRIYLYSLHSAQLL 896
+A G + I ++++ + +LL
Sbjct: 1087 LLATGDDNGEIRIWNVSNGELL 1108
Score = 52.0 bits (119), Expect = 2e-05
Identities = 44/205 (21%), Positives = 86/205 (41%), Gaps = 12/205 (5%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC +S Q A G G + + +L +R+ + H + + F+ + ++S S+
Sbjct: 910 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 969
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSG-----I 1083
D + VW + + +GH ++ ++ + R +S V VW + +G
Sbjct: 970 DAEIQVWNWQLDK-CIFLRGHQETVKDFRLLKNSR-LLSWSFDGTVKVWNIITGNKEKDF 1027
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
V H T S D++ + + D + +IWS D H + C A +
Sbjct: 1028 VCHQGT--VLSCDISHDATKFSSTSADKTAKIWSF---DLLLPLHELRGHNGCVRCSAFS 1082
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKL 1168
DS + TG + +++W + G+L
Sbjct: 1083 VDSTLLATGDDNGEIRIWNVSNGEL 1107
Score = 49.6 bits (113), Expect = 8e-05
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 10/142 (7%)
Query: 674 GDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKIL 733
G ++W+I++ +K F H G++L ++ ++ + S D + +W L ++
Sbjct: 1011 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1070
Query: 734 EHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALV---TKLDH-----HRGSVTSVK 785
H V C A V+ +L+ +G D+ + I ++ +G L+ L H G VT +
Sbjct: 1071 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1130
Query: 786 VIQDGNIFITGSQDGTVCTWNV 807
DG + I S G + WNV
Sbjct: 1131 FSPDGKMLI--SAGGYIKWWNV 1150
Score = 46.0 bits (104), Expect = 0.001
Identities = 50/272 (18%), Positives = 106/272 (38%), Gaps = 23/272 (8%)
Query: 997 THRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTL 1056
T+ + + H + FS + + S D+T+ V++ L K H +
Sbjct: 593 TNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCC 652
Query: 1057 LMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID---VTLNMKYAVLSDG--DN 1111
+D R + + V +W +G ++H+ S ++ T + + +L+ G D
Sbjct: 653 AFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDC 712
Query: 1112 SVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGG----- 1166
+++W L + E H + + D + + + S D +LK+W
Sbjct: 713 FLKLWDL---NQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKS 769
Query: 1167 -KLSQVLVGHSD-------IVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXX 1218
+ Q + D IV C + S +V+ + +W+ ++
Sbjct: 770 INVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAK--NKIFLWNTDSRSKVADCRGH 827
Query: 1219 XXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
V V + DG+ ++ ++D+T+ +WETK+
Sbjct: 828 LSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK 859
Score = 44.0 bits (99), Expect = 0.004
Identities = 33/146 (22%), Positives = 58/146 (39%), Gaps = 4/146 (2%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
GQ + + Q++ + K+ K H +LC + + +++ T S D V +W+
Sbjct: 616 GQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNS 675
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRS---LVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
T + EH V C N S L+ +G D + + L + H S
Sbjct: 676 MTGELVHTYDEHSEQVNC-CHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNS 734
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWN 806
V + D + + S DGT+ W+
Sbjct: 735 VNHCRFSPDDKLLASCSADGTLKLWD 760
Score = 42.3 bits (95), Expect = 0.012
Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 9/147 (6%)
Query: 988 GLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYK 1047
G V+VW + T + H G + S + S S D+T +W P +
Sbjct: 1011 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1070
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH---------SATGPSASIDVT 1098
GH+ ++ D + D + +W V +G +LH +AT D+
Sbjct: 1071 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1130
Query: 1099 LNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+ +L ++ W++ G++S+
Sbjct: 1131 FSPDGKMLISAGGYIKWWNVVTGESSQ 1157
Score = 41.1 bits (92), Expect = 0.028
Identities = 40/199 (20%), Positives = 79/199 (39%), Gaps = 7/199 (3%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
L+P Q++ G ++ +++N + H ++ + T + + L++ S+D +
Sbjct: 915 LSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQ 974
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
VW+ K L + ++ S ++S D V + +++ G H+G
Sbjct: 975 VWNWQ--LDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1032
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV---TAGVPIHIFDVTDDNVFLLT 836
+V S + D F + S D T W+ + L + V F V D+ L T
Sbjct: 1033 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSV--DSTLLAT 1090
Query: 837 LQGDNELHLRTFITGTYLH 855
+ E+ + G LH
Sbjct: 1091 GDDNGEIRIWNVSNGELLH 1109
Score = 40.3 bits (90), Expect = 0.050
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 3/104 (2%)
Query: 951 KSTTNIT-LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIG 1009
K+ TN++ L+ +D + +C S DGQ AS A ++V++ T + H
Sbjct: 590 KNITNLSRLVVRPHTDAVYHACF--SEDGQRIASCGADKTLQVFKAETGEKLLEIKAHED 647
Query: 1010 HITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
+ C FS ++ + + S D+ V +W TY HS +
Sbjct: 648 EVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQV 691
Score = 37.5 bits (83), Expect = 0.35
Identities = 26/118 (22%), Positives = 49/118 (41%)
Query: 918 LAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRD 977
+ A + V +F T+D + + T + E S+ + S
Sbjct: 642 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSH 701
Query: 978 GQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVW 1035
L A+G + +++W L+ + T+ GH + FSP++ L+ S S D T+ +W
Sbjct: 702 HLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 759
Score = 35.1 bits (77), Expect = 1.9
Identities = 26/117 (22%), Positives = 47/117 (40%), Gaps = 2/117 (1%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ ++ C + + Q + + D ++ V+ T +I H VLC A + +
Sbjct: 603 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 662
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
+ D V I + + G LV D H V + + TGS D + W++
Sbjct: 663 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 719
>AF070603-1|AAC28655.1| 207|Homo sapiens beta-subunit signal
transducing proteins GS/GI protein.
Length = 207
Score = 76.6 bits (180), Expect = 6e-13
Identities = 53/213 (24%), Positives = 95/213 (44%), Gaps = 12/213 (5%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R+ L GH G+++C F +N +V S S D T +W + + T+ GH+ + +L +
Sbjct: 1 RVSRELAGHTGYLSCCRFLDDNQIVTS-SGDTTCALWDIETGQQTTTFTGHTGDVMSLSL 59
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NMKYAVLSDGDNSVRI 1115
D R +S + +W V G+ + TG + I+ N D + R+
Sbjct: 60 APDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRL 119
Query: 1116 WSLAGGDNSEDNRRSVSHAE---RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+ L ++ + SH IT + + + ++ G D + VW + VL
Sbjct: 120 FDL----RADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVL 175
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 176 AGHDNRVSCLGVT-DDGMAVATGSWDSFLKIWN 207
Score = 68.1 bits (159), Expect = 2e-10
Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + T GH G + ++ +P+ L +SG+
Sbjct: 13 LSCCRFLDDNQIVTSS-GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 71
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRR-AMSSDRAR-NVHVWLVDSGIVLH 1086
D + +W + + T+ GH S I + +G A SD A + D ++ +
Sbjct: 72 DASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY 131
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V+ + +L G D + +W D + H R++C +T
Sbjct: 132 SHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRA---GVLAGHDNRVSCLGVT 188
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 189 DDGMAVATGSWDSFLKIW 206
Score = 63.3 bits (147), Expect = 6e-09
Identities = 46/201 (22%), Positives = 84/201 (41%), Gaps = 4/201 (1%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T T H V+ ++ + L
Sbjct: 8 GHTGYLSC-CRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLF 66
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT 811
+SG D++ + + +G H + ++ +GN F TGS D T +++
Sbjct: 67 VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 126
Query: 812 LLSTVT-AGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
L T + + I V+ L L G ++ + + + L H +V C
Sbjct: 127 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLG 186
Query: 869 VAHDSSRVAVGCADQRIYLYS 889
V D VA G D + +++
Sbjct: 187 VTDDGMAVATGSWDSFLKIWN 207
Score = 57.6 bits (133), Expect = 3e-07
Identities = 43/183 (23%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Query: 669 LAPSAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+ S+GD LW I + + TF GH+G ++ + + +++ ++G+ D S +WD+
Sbjct: 24 IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 83
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSV 784
+ H + + + N + +G DD+ + L D L+T D+ +TSV
Sbjct: 84 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSV 143
Query: 785 KVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNE 842
+ G + + G D W+ + V AG + VTDD + + T D+
Sbjct: 144 SFSKSGRLLLAGYDDFNCNVWDALKAD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSF 202
Query: 843 LHL 845
L +
Sbjct: 203 LKI 205
Score = 49.6 bits (113), Expect = 8e-05
Identities = 38/151 (25%), Positives = 60/151 (39%), Gaps = 2/151 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP + V +LW + TF GH I +C TGS+D +
Sbjct: 57 LSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDAT 116
Query: 718 VIVWDLHT-LAVKTKILEH-IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
++DL + T ++ I + V+ + L+++G DD + + L
Sbjct: 117 CRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLA 176
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 177 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 207
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 1167 KLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVK 1226
++S+ L GH+ ++C N Q+V+ S D +WDI T V +
Sbjct: 1 RVSRELAGHTGYLSCCRFLDDN--QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLS 58
Query: 1227 VTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
+ D + VS A D + +W+ + G+ +F+ H
Sbjct: 59 LAPDTRLFVSGACDASAKLWDVREGMCRQTFTGH 92
Score = 44.8 bits (101), Expect = 0.002
Identities = 29/145 (20%), Positives = 55/145 (37%), Gaps = 6/145 (4%)
Query: 1105 VLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLD 1164
V S GD + +W + G + H + +L D++ V+G+ D S K+W +
Sbjct: 25 VTSSGDTTCALWDIETG---QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVR 81
Query: 1165 GGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KV 1222
G Q GH + + N +GS D ++D+ +
Sbjct: 82 EGMCRQTFTGHESDINAICF-FPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGI 140
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWE 1247
T V + G + ++ +D +W+
Sbjct: 141 TSVSFSKSGRLLLAGYDDFNCNVWD 165
Score = 44.4 bits (100), Expect = 0.003
Identities = 27/133 (20%), Positives = 61/133 (45%), Gaps = 4/133 (3%)
Query: 1127 NRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSI 1186
+R H ++C D+Q +VT S D + +W ++ G+ + GH+ V +++S+
Sbjct: 3 SRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFTGHTGDV--MSLSL 59
Query: 1187 TNKTQV-VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLII 1245
T++ VSG+ D + +WD+ + + +G + ++D T +
Sbjct: 60 APDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRL 119
Query: 1246 WETKRGLALTSFS 1258
++ + L ++S
Sbjct: 120 FDLRADQELMTYS 132
Score = 43.6 bits (98), Expect = 0.005
Identities = 42/204 (20%), Positives = 79/204 (38%), Gaps = 10/204 (4%)
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSG---IVLHSATGPSASIDVTLNMKYA 1104
GH+ + + D + SS +W +++G TG S+ + + +
Sbjct: 8 GHTGYLSCCRFLDDNQIVTSSGDT-TCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLF 66
Query: 1105 VLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLD 1164
V D S ++W + G + H I + TGS D + +++ L
Sbjct: 67 VSGACDASAKLWDVREG---MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLR 123
Query: 1165 GGKLSQVLVGHSDIVTCV-AVSITNKTQVV-SGSWDCNLIVWDINTXXXXXXXXXXXXKV 1222
+ + H +I+ + +VS + +++ +G D N VWD +V
Sbjct: 124 ADQ-ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRV 182
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIW 1246
+C+ VT DG + + D L IW
Sbjct: 183 SCLGVTDDGMAVATGSWDSFLKIW 206
>CR457333-1|CAG33614.1| 305|Homo sapiens REC14 protein.
Length = 305
Score = 76.2 bits (179), Expect = 8e-13
Identities = 71/270 (26%), Positives = 112/270 (41%), Gaps = 9/270 (3%)
Query: 983 SGCARGLVRVWQLSTHRL--QATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN 1040
+G LV+VW+ RL Q +L GH + V S + S S D + +W L +
Sbjct: 37 TGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENG 96
Query: 1041 SPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA---SIDV 1097
+ TL D + + V+++ V+SG +S SI
Sbjct: 97 KQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAY 156
Query: 1098 TLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMS 1157
+ + KY D + I+ +A G HA I + DSQ +VT S D
Sbjct: 157 SPDGKYLASGAIDGIINIFDIATGKLLHTLE---GHAMPIRSLTFSPDSQLLVTASDDGY 213
Query: 1158 LKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXX 1217
+K++ + L+ L GH+ V VA + T VS S D N+ VWD+ T
Sbjct: 214 IKIYDVQHANLAGTLGGHASWVLNVAFC-PDDTHFVSSSSDKNVKVWDVGTRTCVHTFFD 272
Query: 1218 XXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+V VK G+G+ VS +D+ + I++
Sbjct: 273 HQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302
Score = 67.3 bits (157), Expect = 4e-10
Identities = 35/119 (29%), Positives = 65/119 (54%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I + S DG+ ASG G++ ++ ++T +L TL GH I +TFSP++ L+++ S+
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASD 210
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHS 1087
D + ++ + + + T GH+S + + D +SS +NV VW V + +H+
Sbjct: 211 DGYIKIYDVQHANLAGTLGGHASWVLNVAFCPDDTHFVSSSSDKNVKVWDVGTRTCVHT 269
Score = 57.6 bits (133), Expect = 3e-07
Identities = 50/245 (20%), Positives = 109/245 (44%), Gaps = 5/245 (2%)
Query: 1019 NNLLVLSGSEDRTVVVWQLADNSPSLTY--KGHSSAIQTLLMMSDGRRAMSSDRARNVHV 1076
N+ V++GS D V VW+ D L + +GH + ++ + A SS ++ +
Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRL 90
Query: 1077 WLVDSGIVLHSA-TGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE 1135
W +++G + S GP + + + L+ G + ++ ++ G ++ + + +
Sbjct: 91 WDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKV-NIFGVESGKKEYSLDTRGK 149
Query: 1136 RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSG 1195
I A + D +++ +G++D + ++ + GKL L GH+ + + S ++ +V+
Sbjct: 150 FILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQL-LVTA 208
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALT 1255
S D + ++D+ V V D T VS + DK + +W+ +
Sbjct: 209 SDDGYIKIYDVQHANLAGTLGGHASWVLNVAFCPDDTHFVSSSSDKNVKVWDVGTRTCVH 268
Query: 1256 SFSLH 1260
+F H
Sbjct: 269 TFFDH 273
Score = 55.6 bits (128), Expect = 1e-06
Identities = 29/120 (24%), Positives = 54/120 (45%)
Query: 958 LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFS 1017
LL + +PI L S D QL + G ++++ + L TL GH + V F
Sbjct: 182 LLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLGGHASWVLNVAFC 241
Query: 1018 PNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
P++ +S S D+ V VW + + T+ H + + +G + +S + +H++
Sbjct: 242 PDDTHFVSSSSDKNVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIY 301
Score = 53.2 bits (122), Expect = 7e-06
Identities = 42/214 (19%), Positives = 91/214 (42%), Gaps = 3/214 (1%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
+LW + + ++ + + + +SQYL TG+ V ++ + + + +
Sbjct: 89 RLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRG 148
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
+L +A + + SG D + I + G L+ L+ H + S+ D + +T
Sbjct: 149 KFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTA 208
Query: 797 SQDGTVCTWNVENFTLLSTVTAGVPIHIFDVT--DDNVFLLTLQGDNELHLRTFITGTYL 854
S DG + ++V++ L T+ G + +V D+ ++ D + + T T +
Sbjct: 209 SDDGYIKIYDVQHANLAGTL-GGHASWVLNVAFCPDDTHFVSSSSDKNVKVWDVGTRTCV 267
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
H H+ +V + S++ DQ I++Y
Sbjct: 268 HTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIY 301
Score = 48.8 bits (111), Expect = 1e-04
Identities = 44/237 (18%), Positives = 98/237 (41%), Gaps = 7/237 (2%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRT 1031
+++S + AS +R+W L + +++ + FSP++ + +G+
Sbjct: 70 VDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGK 129
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG- 1090
V ++ + + I ++ DG+ S ++++ + +G +LH+ G
Sbjct: 130 VNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGH 189
Query: 1091 --PSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQH 1148
P S+ + + + V + D ++I+ + ++ HA + A D H
Sbjct: 190 AMPIRSLTFSPDSQLLVTASDDGYIKIYDV---QHANLAGTLGGHASWVLNVAFCPDDTH 246
Query: 1149 VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
V+ S D ++KVW + H D V V + N +++VS D + ++D
Sbjct: 247 FVSSSSDKNVKVWDVGTRTCVHTFFDHQDQVWGVKYN-GNGSKIVSVGDDQEIHIYD 302
Score = 48.0 bits (109), Expect = 2e-04
Identities = 32/139 (23%), Positives = 63/139 (45%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+P G++L G ++ I + +HT +GH+ I + + +SQ L+T S+D + +
Sbjct: 157 SPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKI 216
Query: 721 WDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
+D+ + + H + VL VA + + +S D V + + V H+
Sbjct: 217 YDVQHANLAGTLGGHASWVLNVAFCPDDTHFVSSSSDKNVKVWDVGTRTCVHTFFDHQDQ 276
Query: 781 VTSVKVIQDGNIFITGSQD 799
V VK +G+ ++ D
Sbjct: 277 VWGVKYNGNGSKIVSVGDD 295
Score = 46.8 bits (106), Expect = 6e-04
Identities = 29/107 (27%), Positives = 48/107 (44%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R L +P Q LV A G +++ + + T GH+ +L + + + ++ S D
Sbjct: 194 RSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLGGHASWVLNVAFCPDDTHFVSSSSD 253
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVII 762
+V VWD+ T +H V V N S ++S GDD + I
Sbjct: 254 KNVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHI 300
Score = 41.9 bits (94), Expect = 0.016
Identities = 32/164 (19%), Positives = 75/164 (45%), Gaps = 5/164 (3%)
Query: 960 QAEQSDLIPISC--LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFS 1017
Q + D P+ L S D Q A+G G V ++ + + + + +L+ I + +S
Sbjct: 98 QIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYS 157
Query: 1018 PNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
P+ + SG+ D + ++ +A T +GH+ I++L D + +++ + ++
Sbjct: 158 PDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIY 217
Query: 1078 LVDSGIVLHSATGPSA---SIDVTLNMKYAVLSDGDNSVRIWSL 1118
V + + G ++ ++ + + V S D +V++W +
Sbjct: 218 DVQHANLAGTLGGHASWVLNVAFCPDDTHFVSSSSDKNVKVWDV 261
Score = 36.7 bits (81), Expect = 0.61
Identities = 36/211 (17%), Positives = 76/211 (36%), Gaps = 1/211 (0%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
+ +GH ++ + ++ + S D + +WDL I +A +
Sbjct: 59 SLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDS 118
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
+ +G V I + G LD + S+ DG +G+ DG + +++
Sbjct: 119 QYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIA 178
Query: 809 NFTLLSTVTA-GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCF 867
LL T+ +PI + D+ L+T D + + L H + V
Sbjct: 179 TGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLGGHASWVLNV 238
Query: 868 CVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
D + +D+ + ++ + + + T
Sbjct: 239 AFCPDDTHFVSSSSDKNVKVWDVGTRTCVHT 269
Score = 35.9 bits (79), Expect = 1.1
Identities = 34/155 (21%), Positives = 65/155 (41%), Gaps = 3/155 (1%)
Query: 747 NRSLVISGGDDSAVIITSLVDGALVTK--LDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
N V++G D V + D L + L+ H+ V SV + I + S D +
Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRL 90
Query: 805 WNVENFTLLSTVTAG-VPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAK 863
W++EN + ++ AG V + D+ +L T ++++ +G + L
Sbjct: 91 WDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKF 150
Query: 864 VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ + D +A G D I ++ + + +LL T
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT 185
>AJ243107-1|CAB56462.1| 1171|Homo sapiens apoptotic protease
activating factor-1 protein.
Length = 1171
Score = 76.2 bits (179), Expect = 8e-13
Identities = 88/430 (20%), Positives = 165/430 (38%), Gaps = 28/430 (6%)
Query: 828 TDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRV--AVGCADQRI 885
TDD F+ T D ++ + +TG +H H +V C + S + A G +D +
Sbjct: 675 TDDR-FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFL 733
Query: 886 YLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQM 945
L+ L+ + T LA S + L + T
Sbjct: 734 KLWDLNQKECRNTMFGHTNSVNHCRFSPDDKPLA---------SCSADGTLKLWDATSAN 784
Query: 946 KRRQTKSTTNITLLQAEQSDL-IPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATL 1004
+R+ L+ Q D+ + + C S DG A+ + +W + A
Sbjct: 785 ERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGAR-IMVAAKNKIFLWNTDSRSKVADC 843
Query: 1005 NGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQ---LADNSPSLTYKGHSSAIQTLLMMSD 1061
GH+ + V FSP+ L+ S+D+T+ +W+ + NS + + Q +M
Sbjct: 844 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVM-- 901
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGG 1121
++ D R + + +G + + + ++ +++Y D + ++ I L
Sbjct: 902 ---VLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELV-- 956
Query: 1122 DNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTC 1181
N+ + H + + TAD + +++ S D ++VW K L GH + T
Sbjct: 957 -NNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCI-FLRGHQE--TV 1012
Query: 1182 VAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDK 1241
+ ++++S S+D + VW+I T V ++ D T S + DK
Sbjct: 1013 KDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADK 1072
Query: 1242 TLIIWETKRG 1251
T IW G
Sbjct: 1073 TAKIWNVSNG 1082
Score = 61.7 bits (143), Expect = 2e-08
Identities = 35/147 (23%), Positives = 63/147 (42%), Gaps = 1/147 (0%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKT 1190
+H + + C A + D + + T S+D +K+W G+L HS+ V C + ++
Sbjct: 663 AHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHL 722
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
+ +GS DC L +WD+N V + + D SC+ D TL +W+
Sbjct: 723 LLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKPLASCSADGTLKLWDATS 782
Query: 1251 GLALTSFSLHVPLLGFQITSDCARVVV 1277
S ++ L + + V+V
Sbjct: 783 ANERKSINVKQFFLNLEDPQEDMEVIV 809
Score = 46.8 bits (106), Expect = 6e-04
Identities = 34/154 (22%), Positives = 66/154 (42%), Gaps = 2/154 (1%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
L+P Q++ G ++ +++N + H ++ + T + + L++ S+D +
Sbjct: 934 LSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQ 993
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
VW+ K L + ++ S ++S D V + +++ G H+G
Sbjct: 994 VWNWQL--DKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1051
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLL 813
+V S + D F + S D T WNV N LL
Sbjct: 1052 TVLSCDISHDATKFSSTSADKTAKIWNVSNGELL 1085
Score = 46.4 bits (105), Expect = 8e-04
Identities = 50/272 (18%), Positives = 106/272 (38%), Gaps = 23/272 (8%)
Query: 997 THRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTL 1056
T+ + + H + FS + + S D+T+ V++ L K H +
Sbjct: 612 TNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCC 671
Query: 1057 LMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID---VTLNMKYAVLSDG--DN 1111
+D R + + V +W +G ++H+ S ++ T + + +L+ G D
Sbjct: 672 AFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDC 731
Query: 1112 SVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGG----- 1166
+++W L + E H + + D + + + S D +LK+W
Sbjct: 732 FLKLWDL---NQKECRNTMFGHTNSVNHCRFSPDDKPLASCSADGTLKLWDATSANERKS 788
Query: 1167 -KLSQVLVGHSD-------IVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXX 1218
+ Q + D IV C + S +V+ + +W+ ++
Sbjct: 789 INVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAK--NKIFLWNTDSRSKVADCRGH 846
Query: 1219 XXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
V V + DG+ ++ ++D+T+ +WETK+
Sbjct: 847 LSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK 878
Score = 46.0 bits (104), Expect = 0.001
Identities = 32/160 (20%), Positives = 67/160 (41%), Gaps = 6/160 (3%)
Query: 1011 ITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDR 1070
++C SP+ + G E+ + + +L +N + H + + +D + +SS
Sbjct: 929 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 988
Query: 1071 ARNVHVW--LVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNR 1128
+ VW +D I L + N + S D +V++W++ G+ +D
Sbjct: 989 DAEIQVWNWQLDKCIFLRGHQETVKDFRLLKNSRLLSWSF-DGTVKVWNIITGNKEKD-- 1045
Query: 1129 RSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKL 1168
V H + ++ D+ + S D + K+W + G+L
Sbjct: 1046 -FVCHQGTVLSCDISHDATKFSSTSADKTAKIWNVSNGEL 1084
Score = 41.9 bits (94), Expect = 0.016
Identities = 33/146 (22%), Positives = 57/146 (39%), Gaps = 4/146 (2%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
GQ + + Q++ + K+ K H +LC + + +++ T S D V +W+
Sbjct: 635 GQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNS 694
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRS---LVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
T + EH V C N S L+ +G D + + L + H S
Sbjct: 695 MTGELVHTYDEHSEQVNC-CHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNS 753
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWN 806
V + D + S DGT+ W+
Sbjct: 754 VNHCRFSPDDKPLASCSADGTLKLWD 779
Score = 41.5 bits (93), Expect = 0.021
Identities = 32/160 (20%), Positives = 66/160 (41%), Gaps = 1/160 (0%)
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
A V C + + G ++ A+ I LV+ + H+ +V ++ D I+
Sbjct: 927 AQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISS 986
Query: 797 SQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
S D + WN + + + F + N LL+ D + + ITG
Sbjct: 987 SDDAEIQVWNWQLDKCIFLRGHQETVKDFRLLK-NSRLLSWSFDGTVKVWNIITGNKEKD 1045
Query: 857 LKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
H+ V ++HD+++ + AD+ ++++ + +LL
Sbjct: 1046 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWNVSNGELL 1085
Score = 40.3 bits (90), Expect = 0.050
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 3/104 (2%)
Query: 951 KSTTNIT-LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIG 1009
K+ TN++ L+ +D + +C S DGQ AS A ++V++ T + H
Sbjct: 609 KNITNLSRLVVRPHTDAVYHACF--SEDGQRIASCGADKTLQVFKAETGEKLLEIKAHED 666
Query: 1010 HITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
+ C FS ++ + + S D+ V +W TY HS +
Sbjct: 667 EVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQV 710
Score = 39.5 bits (88), Expect = 0.087
Identities = 24/112 (21%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Query: 697 ILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGD 756
+ C C++ QY+ G E+ ++ + +L + +H V + + +IS D
Sbjct: 929 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 988
Query: 757 DSAVIITS-LVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
D+ + + + +D + L H+ +V +++++ + ++ S DGTV WN+
Sbjct: 989 DAEIQVWNWQLDKCIF--LRGHQETVKDFRLLKNSRL-LSWSFDGTVKVWNI 1037
Score = 35.1 bits (77), Expect = 1.9
Identities = 26/117 (22%), Positives = 47/117 (40%), Gaps = 2/117 (1%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ ++ C + + Q + + D ++ V+ T +I H VLC A + +
Sbjct: 622 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 681
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
+ D V I + + G LV D H V + + TGS D + W++
Sbjct: 682 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 738
Score = 35.1 bits (77), Expect = 1.9
Identities = 30/145 (20%), Positives = 58/145 (40%), Gaps = 11/145 (7%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
++VW + L GH + N+ L LS S D TV VW + + + H
Sbjct: 992 IQVWNWQLDKC-IFLRGHQETVKDFRLLKNSRL-LSWSFDGTVKVWNIITGNKEKDFVCH 1049
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH---------SATGPSASIDVTLN 1100
+ + + D + S+ + +W V +G +LH +AT D+ +
Sbjct: 1050 QGTVLSCDISHDATKFSSTSADKTAKIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFS 1109
Query: 1101 MKYAVLSDGDNSVRIWSLAGGDNSE 1125
+L ++ W++ G++S+
Sbjct: 1110 PDGKMLISAGGYIKWWNVVTGESSQ 1134
Score = 34.7 bits (76), Expect = 2.5
Identities = 25/118 (21%), Positives = 48/118 (40%)
Query: 918 LAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRD 977
+ A + V +F T+D + + T + E S+ + S
Sbjct: 661 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSH 720
Query: 978 GQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVW 1035
L A+G + +++W L+ + T+ GH + FSP++ + S S D T+ +W
Sbjct: 721 HLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKPLASCSADGTLKLW 778
>AJ243011-1|CAB55587.1| 1205|Homo sapiens protease activating factor-1
protein.
Length = 1205
Score = 76.2 bits (179), Expect = 8e-13
Identities = 96/460 (20%), Positives = 176/460 (38%), Gaps = 37/460 (8%)
Query: 828 TDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRV--AVGCADQRI 885
TDD F+ T D ++ + +TG +H H +V C + S + A G +D +
Sbjct: 667 TDDR-FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFL 725
Query: 886 YLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQM 945
L+ L+ + T LLA S + L + T
Sbjct: 726 KLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLA---------SCSADGTLKLWDATSAN 776
Query: 946 KRRQTKSTTNITLLQAEQSDL-IPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATL 1004
+R+ L+ Q D+ + + C S DG A+ + +W A
Sbjct: 777 ERKSINVKQFFLNLEDPQEDMGVIVKCCSWSADGAR-IMVAAKNKIFLWNTDLRSKVADC 835
Query: 1005 NGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQ---LADNSPSLTYKGHSSAIQTLLMMSD 1061
GH+ + V FSP+ L+ S+D+T+ +W+ + NS + + Q +M
Sbjct: 836 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVM-- 893
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGG 1121
++ D R + + +G + + + ++ +++Y D + ++ I L
Sbjct: 894 ---VLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELV-- 948
Query: 1122 DNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTC 1181
N+ + H + + TAD + +++ S D ++VW K L GH + T
Sbjct: 949 -NNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCI-FLRGHQE--TV 1004
Query: 1182 VAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDK 1241
+ ++++S S+D + VW+I T V ++ D T S + DK
Sbjct: 1005 KDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADK 1064
Query: 1242 TLIIWETKRGLALTSFSLHVPLLGFQITSDCARVVVHLLD 1281
T IW SF L +PL + + C R +D
Sbjct: 1065 TAKIW---------SFDLLLPLHELRGHNGCVRCSAFSVD 1095
Score = 63.3 bits (147), Expect = 6e-09
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 1/117 (0%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKT 1190
+H + + C A + D + + T S+D +K+W G+L HS+ V C + ++
Sbjct: 655 AHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHL 714
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+ +GS DC L +WD+N V + + D + SC+ D TL +W+
Sbjct: 715 LLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 53.6 bits (123), Expect = 5e-06
Identities = 42/202 (20%), Positives = 91/202 (45%), Gaps = 5/202 (2%)
Query: 697 ILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGD 756
+ C C++ QY+ G E+ ++ + +L + +H V + + +IS D
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 757 DSAVIITSL-VDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLST 815
D+ + + + +D + L H+ +V +++++ + ++ S DGTV WN+
Sbjct: 981 DAEIQVWNWQLDKCIF--LRGHQETVKDFRLLKNSRL-LSWSFDGTVKVWNIITGNKEKD 1037
Query: 816 -VTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSS 874
V + D++ D + D + +F LH L+ H V+C + DS+
Sbjct: 1038 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST 1097
Query: 875 RVAVGCADQRIYLYSLHSAQLL 896
+A G + I ++++ + +LL
Sbjct: 1098 LLATGDDNGEIRIWNVSNGELL 1119
Score = 52.0 bits (119), Expect = 2e-05
Identities = 44/205 (21%), Positives = 86/205 (41%), Gaps = 12/205 (5%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC +S Q A G G + + +L +R+ + H + + F+ + ++S S+
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSG-----I 1083
D + VW + + +GH ++ ++ + R +S V VW + +G
Sbjct: 981 DAEIQVWNWQLDK-CIFLRGHQETVKDFRLLKNSR-LLSWSFDGTVKVWNIITGNKEKDF 1038
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
V H T S D++ + + D + +IWS D H + C A +
Sbjct: 1039 VCHQGT--VLSCDISHDATKFSSTSADKTAKIWSF---DLLLPLHELRGHNGCVRCSAFS 1093
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKL 1168
DS + TG + +++W + G+L
Sbjct: 1094 VDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 49.6 bits (113), Expect = 8e-05
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 10/142 (7%)
Query: 674 GDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKIL 733
G ++W+I++ +K F H G++L ++ ++ + S D + +W L ++
Sbjct: 1022 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1081
Query: 734 EHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALV---TKLDH-----HRGSVTSVK 785
H V C A V+ +L+ +G D+ + I ++ +G L+ L H G VT +
Sbjct: 1082 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1141
Query: 786 VIQDGNIFITGSQDGTVCTWNV 807
DG + I S G + WNV
Sbjct: 1142 FSPDGKMLI--SAGGYIKWWNV 1161
Score = 45.2 bits (102), Expect = 0.002
Identities = 50/272 (18%), Positives = 105/272 (38%), Gaps = 23/272 (8%)
Query: 997 THRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTL 1056
T+ + + H + FS + + S D+T+ V++ L K H +
Sbjct: 604 TNLSRLVVRPHTDAVYRACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCC 663
Query: 1057 LMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID---VTLNMKYAVLSDG--DN 1111
+D R + + V +W +G ++H+ S ++ T + + +L+ G D
Sbjct: 664 AFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDC 723
Query: 1112 SVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGG----- 1166
+++W L + E H + + D + + + S D +LK+W
Sbjct: 724 FLKLWDL---NQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKS 780
Query: 1167 -KLSQVLVGHSD-------IVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXX 1218
+ Q + D IV C + S +V+ + +W+ +
Sbjct: 781 INVKQFFLNLEDPQEDMGVIVKCCSWSADGARIMVAAK--NKIFLWNTDLRSKVADCRGH 838
Query: 1219 XXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
V V + DG+ ++ ++D+T+ +WETK+
Sbjct: 839 LSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK 870
Score = 44.0 bits (99), Expect = 0.004
Identities = 33/146 (22%), Positives = 58/146 (39%), Gaps = 4/146 (2%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
GQ + + Q++ + K+ K H +LC + + +++ T S D V +W+
Sbjct: 627 GQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNS 686
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRS---LVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
T + EH V C N S L+ +G D + + L + H S
Sbjct: 687 MTGELVHTYDEHSEQVNC-CHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNS 745
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWN 806
V + D + + S DGT+ W+
Sbjct: 746 VNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 42.3 bits (95), Expect = 0.012
Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 9/147 (6%)
Query: 988 GLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYK 1047
G V+VW + T + H G + S + S S D+T +W P +
Sbjct: 1022 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1081
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH---------SATGPSASIDVT 1098
GH+ ++ D + D + +W V +G +LH +AT D+
Sbjct: 1082 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1141
Query: 1099 LNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+ +L ++ W++ G++S+
Sbjct: 1142 FSPDGKMLISAGGYIKWWNVVTGESSQ 1168
Score = 41.1 bits (92), Expect = 0.028
Identities = 40/199 (20%), Positives = 79/199 (39%), Gaps = 7/199 (3%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
L+P Q++ G ++ +++N + H ++ + T + + L++ S+D +
Sbjct: 926 LSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQ 985
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
VW+ K L + ++ S ++S D V + +++ G H+G
Sbjct: 986 VWNWQ--LDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1043
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV---TAGVPIHIFDVTDDNVFLLT 836
+V S + D F + S D T W+ + L + V F V D+ L T
Sbjct: 1044 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSV--DSTLLAT 1101
Query: 837 LQGDNELHLRTFITGTYLH 855
+ E+ + G LH
Sbjct: 1102 GDDNGEIRIWNVSNGELLH 1120
Score = 40.3 bits (90), Expect = 0.050
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 3/104 (2%)
Query: 951 KSTTNIT-LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIG 1009
K+ TN++ L+ +D + +C S DGQ AS A ++V++ T + H
Sbjct: 601 KNITNLSRLVVRPHTDAVYRACF--SEDGQRIASCGADKTLQVFKAETGEKLLEIKAHED 658
Query: 1010 HITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
+ C FS ++ + + S D+ V +W TY HS +
Sbjct: 659 EVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQV 702
Score = 37.5 bits (83), Expect = 0.35
Identities = 26/118 (22%), Positives = 49/118 (41%)
Query: 918 LAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRD 977
+ A + V +F T+D + + T + E S+ + S
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSH 712
Query: 978 GQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVW 1035
L A+G + +++W L+ + T+ GH + FSP++ L+ S S D T+ +W
Sbjct: 713 HLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 770
Score = 35.1 bits (77), Expect = 1.9
Identities = 26/117 (22%), Positives = 47/117 (40%), Gaps = 2/117 (1%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ ++ C + + Q + + D ++ V+ T +I H VLC A + +
Sbjct: 614 HTDAVYRACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
+ D V I + + G LV D H V + + TGS D + W++
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
>AJ243006-1|CAB55582.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 76.2 bits (179), Expect = 8e-13
Identities = 96/460 (20%), Positives = 176/460 (38%), Gaps = 37/460 (8%)
Query: 828 TDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRV--AVGCADQRI 885
TDD F+ T D ++ + +TG +H H +V C + S + A G +D +
Sbjct: 667 TDDR-FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFL 725
Query: 886 YLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQM 945
L+ L+ + T LLA S + L + T
Sbjct: 726 KLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLA---------SCSADGTLKLWDATSAN 776
Query: 946 KRRQTKSTTNITLLQAEQSDL-IPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATL 1004
+R+ L+ Q D+ + + C S DG A+ + +W + A
Sbjct: 777 ERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGAR-IMVAAKNKIFLWNTDSRSKVADC 835
Query: 1005 NGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQ---LADNSPSLTYKGHSSAIQTLLMMSD 1061
GH+ + V FSP+ L+ S+D+T+ +W+ + NS + + Q +M
Sbjct: 836 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVM-- 893
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGG 1121
++ D R + + +G + + + ++ +++Y D + ++ I L
Sbjct: 894 ---VLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELV-- 948
Query: 1122 DNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTC 1181
N+ + H + + TAD + +++ S D ++VW K L GH + T
Sbjct: 949 -NNRIFQSRFQHKKTVWRIQFTADEKTLISSSDDAEIQVWNWQLDKCI-FLRGHQE--TV 1004
Query: 1182 VAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDK 1241
+ +++S S+D + VW+I T V ++ D T S + DK
Sbjct: 1005 KDFRLLKNPRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADK 1064
Query: 1242 TLIIWETKRGLALTSFSLHVPLLGFQITSDCARVVVHLLD 1281
T IW SF L +PL + + C R +D
Sbjct: 1065 TAKIW---------SFDLLLPLHELRGHNGCVRCSAFSVD 1095
Score = 63.7 bits (148), Expect = 5e-09
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 1/147 (0%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKT 1190
+H + + C A + D + + T S+D +K+W G+L HS+ V C + ++
Sbjct: 655 AHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHL 714
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
+ +GS DC L +WD+N V + + D + SC+ D TL +W+
Sbjct: 715 LLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATS 774
Query: 1251 GLALTSFSLHVPLLGFQITSDCARVVV 1277
S ++ L + + V+V
Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIV 801
Score = 52.8 bits (121), Expect = 9e-06
Identities = 42/202 (20%), Positives = 91/202 (45%), Gaps = 5/202 (2%)
Query: 697 ILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGD 756
+ C C++ QY+ G E+ ++ + +L + +H V + + +IS D
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWRIQFTADEKTLISSSD 980
Query: 757 DSAVIITSL-VDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLST 815
D+ + + + +D + L H+ +V +++++ + ++ S DGTV WN+
Sbjct: 981 DAEIQVWNWQLDKCIF--LRGHQETVKDFRLLKNPRL-LSWSFDGTVKVWNIITGNKEKD 1037
Query: 816 -VTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSS 874
V + D++ D + D + +F LH L+ H V+C + DS+
Sbjct: 1038 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST 1097
Query: 875 RVAVGCADQRIYLYSLHSAQLL 896
+A G + I ++++ + +LL
Sbjct: 1098 LLATGDDNGEIRIWNVSNGELL 1119
Score = 51.2 bits (117), Expect = 3e-05
Identities = 44/205 (21%), Positives = 86/205 (41%), Gaps = 12/205 (5%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC +S Q A G G + + +L +R+ + H + + F+ + ++S S+
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWRIQFTADEKTLISSSD 980
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSG-----I 1083
D + VW + + +GH ++ ++ + R +S V VW + +G
Sbjct: 981 DAEIQVWNWQLDK-CIFLRGHQETVKDFRLLKNPR-LLSWSFDGTVKVWNIITGNKEKDF 1038
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
V H T S D++ + + D + +IWS D H + C A +
Sbjct: 1039 VCHQGT--VLSCDISHDATKFSSTSADKTAKIWSF---DLLLPLHELRGHNGCVRCSAFS 1093
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKL 1168
DS + TG + +++W + G+L
Sbjct: 1094 VDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 49.6 bits (113), Expect = 8e-05
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 10/142 (7%)
Query: 674 GDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKIL 733
G ++W+I++ +K F H G++L ++ ++ + S D + +W L ++
Sbjct: 1022 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1081
Query: 734 EHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALV---TKLDH-----HRGSVTSVK 785
H V C A V+ +L+ +G D+ + I ++ +G L+ L H G VT +
Sbjct: 1082 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1141
Query: 786 VIQDGNIFITGSQDGTVCTWNV 807
DG + I S G + WNV
Sbjct: 1142 FSPDGKMLI--SAGGYIKWWNV 1161
Score = 46.0 bits (104), Expect = 0.001
Identities = 50/272 (18%), Positives = 106/272 (38%), Gaps = 23/272 (8%)
Query: 997 THRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTL 1056
T+ + + H + FS + + S D+T+ V++ L K H +
Sbjct: 604 TNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCC 663
Query: 1057 LMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID---VTLNMKYAVLSDG--DN 1111
+D R + + V +W +G ++H+ S ++ T + + +L+ G D
Sbjct: 664 AFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDC 723
Query: 1112 SVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGG----- 1166
+++W L + E H + + D + + + S D +LK+W
Sbjct: 724 FLKLWDL---NQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKS 780
Query: 1167 -KLSQVLVGHSD-------IVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXX 1218
+ Q + D IV C + S +V+ + +W+ ++
Sbjct: 781 INVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAK--NKIFLWNTDSRSKVADCRGH 838
Query: 1219 XXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
V V + DG+ ++ ++D+T+ +WETK+
Sbjct: 839 LSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK 870
Score = 44.0 bits (99), Expect = 0.004
Identities = 33/146 (22%), Positives = 58/146 (39%), Gaps = 4/146 (2%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
GQ + + Q++ + K+ K H +LC + + +++ T S D V +W+
Sbjct: 627 GQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNS 686
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRS---LVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
T + EH V C N S L+ +G D + + L + H S
Sbjct: 687 MTGELVHTYDEHSEQVNC-CHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNS 745
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWN 806
V + D + + S DGT+ W+
Sbjct: 746 VNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 42.3 bits (95), Expect = 0.012
Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 9/147 (6%)
Query: 988 GLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYK 1047
G V+VW + T + H G + S + S S D+T +W P +
Sbjct: 1022 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1081
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH---------SATGPSASIDVT 1098
GH+ ++ D + D + +W V +G +LH +AT D+
Sbjct: 1082 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1141
Query: 1099 LNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+ +L ++ W++ G++S+
Sbjct: 1142 FSPDGKMLISAGGYIKWWNVVTGESSQ 1168
Score = 40.3 bits (90), Expect = 0.050
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 3/104 (2%)
Query: 951 KSTTNIT-LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIG 1009
K+ TN++ L+ +D + +C S DGQ AS A ++V++ T + H
Sbjct: 601 KNITNLSRLVVRPHTDAVYHACF--SEDGQRIASCGADKTLQVFKAETGEKLLEIKAHED 658
Query: 1010 HITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
+ C FS ++ + + S D+ V +W TY HS +
Sbjct: 659 EVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQV 702
Score = 39.5 bits (88), Expect = 0.087
Identities = 42/199 (21%), Positives = 79/199 (39%), Gaps = 7/199 (3%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
L+P Q++ G ++ +++N + H ++ + T + + L++ S+D +
Sbjct: 926 LSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWRIQFTADEKTLISSSDDAEIQ 985
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
VW+ L + H V + N L +S D V + +++ G H+G
Sbjct: 986 VWNWQ-LDKCIFLRGHQETVKDFRLLKNPRL-LSWSFDGTVKVWNIITGNKEKDFVCHQG 1043
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV---TAGVPIHIFDVTDDNVFLLT 836
+V S + D F + S D T W+ + L + V F V D+ L T
Sbjct: 1044 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSV--DSTLLAT 1101
Query: 837 LQGDNELHLRTFITGTYLH 855
+ E+ + G LH
Sbjct: 1102 GDDNGEIRIWNVSNGELLH 1120
Score = 37.5 bits (83), Expect = 0.35
Identities = 26/118 (22%), Positives = 49/118 (41%)
Query: 918 LAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRD 977
+ A + V +F T+D + + T + E S+ + S
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSH 712
Query: 978 GQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVW 1035
L A+G + +++W L+ + T+ GH + FSP++ L+ S S D T+ +W
Sbjct: 713 HLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 770
Score = 35.1 bits (77), Expect = 1.9
Identities = 26/117 (22%), Positives = 47/117 (40%), Gaps = 2/117 (1%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ ++ C + + Q + + D ++ V+ T +I H VLC A + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
+ D V I + + G LV D H V + + TGS D + W++
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
>BC047921-1|AAH47921.1| 563|Homo sapiens WDR86 protein protein.
Length = 563
Score = 75.8 bits (178), Expect = 1e-12
Identities = 113/511 (22%), Positives = 186/511 (36%), Gaps = 44/511 (8%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVW 721
PSG L+L P P S + H G I + ++ + Q LLTGSED + +W
Sbjct: 58 PSGAQLLLVPR---PASGMGGGGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLW 114
Query: 722 ---DLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHR 778
D A+ H P L AA ++ D S+ L H
Sbjct: 115 STADGQCCALLQGRPSHSLPDLFAAAHRPQT-----ADPSSCARRPLSRSPAPA----HP 165
Query: 779 GSVTSVKVIQDGNIFITGSQDGTV-CTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTL 837
G++ + + +I++ ++ G V C V N LL + + D +N LL
Sbjct: 166 GTLAEER-LSGPSIWLLSARQGRVPCGLFVANCALL------LAFPVDDSHSNNRRLLRA 218
Query: 838 QGDNELHLRTFITGTYL--HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQL 895
G + + T TY + L H++ V FC D + AD I + + + Q
Sbjct: 219 SGAEKCAVVTLCYPTYRRGNRLGGHESYVT-FCQLEDEAAFTCS-ADCTIRRWDVLTGQC 276
Query: 896 LRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTN 955
L+ ++ ++S FR +
Sbjct: 277 LQVYRGHTSIVNRILVANNQLFSSSYDRTARVWSVDKGQMSREFRGHRNCV--------- 327
Query: 956 ITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVT 1015
+TL + DL C E + G L +G G +VWQ+++ TL GH G + C+
Sbjct: 328 LTLAYSAPWDLPSTPCAEEAAAGGLLVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLV 387
Query: 1016 FSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVH 1075
+GS D T+ W + ++ H ++ L +++ R S R V
Sbjct: 388 LDTPGHTAFTGSTDATIRAWDILSGEQLRVFREHRGSVICLELVN--RLVYSGSADRTVK 445
Query: 1076 VWLVDSGIVLHSATGPSASID-VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHA 1134
WL D+G + + T ++ + + GD R + G E R H
Sbjct: 446 CWLADTGECVRTFTAHRRNVSALKYHAGTLFTGSGDACARAFDAQSG---ELRRVFRGHT 502
Query: 1135 ERITCFALTADSQHVVTGSMDMSLKVWKLDG 1165
I C + Q + T S D +L++W + G
Sbjct: 503 FIINC--IQVHGQVLYTASHDGALRLWDVRG 531
Score = 68.1 bits (159), Expect = 2e-10
Identities = 51/187 (27%), Positives = 88/187 (47%), Gaps = 11/187 (5%)
Query: 1022 LVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDS 1081
L+++GS D T VWQ+A T +GH+ A+ L++ + G A + + W + S
Sbjct: 352 LLVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLVLDTPGHTAFTGSTDATIRAWDILS 411
Query: 1082 GIVLHSATGPSASIDVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITC 1139
G L S+ + L + ++ G D +V+ W LA D E R +H ++
Sbjct: 412 GEQLRVFREHRGSV-ICLELVNRLVYSGSADRTVKCW-LA--DTGECVRTFTAHRRNVS- 466
Query: 1140 FALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDC 1199
AL + + TGS D + + G+L +V GH+ I+ C+ V + + + S D
Sbjct: 467 -ALKYHAGTLFTGSGDACARAFDAQSGELRRVFRGHTFIINCIQV---HGQVLYTASHDG 522
Query: 1200 NLIVWDI 1206
L +WD+
Sbjct: 523 ALRLWDV 529
Score = 67.3 bits (157), Expect = 4e-10
Identities = 44/149 (29%), Positives = 71/149 (47%), Gaps = 4/149 (2%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
A +G LV + G ++W + S T +GH+G++LC+ + TGS D ++
Sbjct: 347 AAAGGLLVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLVLDTPGHTAFTGSTDATIRA 406
Query: 721 WDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
WD+ + EH V+C+ +VNR LV SG D V G V HR +
Sbjct: 407 WDILSGEQLRVFREHRGSVICL-ELVNR-LVYSGSADRTVKCWLADTGECVRTFTAHRRN 464
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
V+++K G +F TGS D ++ ++
Sbjct: 465 VSALK-YHAGTLF-TGSGDACARAFDAQS 491
Score = 59.3 bits (137), Expect = 1e-07
Identities = 60/252 (23%), Positives = 100/252 (39%), Gaps = 17/252 (6%)
Query: 1021 LLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
LL SG+E VV GH S + T + D A + + W V
Sbjct: 215 LLRASGAEKCAVVTLCYPTYRRGNRLGGHESYV-TFCQLED-EAAFTCSADCTIRRWDVL 272
Query: 1081 SGIVLHSATGPSASIDVTLNMKYAVLSDG-DNSVRIWSLAGGDNSEDNRR------SVSH 1133
+G L G ++ ++ L + S D + R+WS+ G S + R ++++
Sbjct: 273 TGQCLQVYRGHTSIVNRILVANNQLFSSSYDRTARVWSVDKGQMSREFRGHRNCVLTLAY 332
Query: 1134 AE-----RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITN 1188
+ C A +VTGS D + KVW++ G Q L GH+ V C+ +
Sbjct: 333 SAPWDLPSTPCAEEAAAGGLLVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLVLDTPG 392
Query: 1189 KTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWET 1248
T +GS D + WDI + V C+++ + S + D+T+ W
Sbjct: 393 HT-AFTGSTDATIRAWDILSGEQLRVFREHRGSVICLELV--NRLVYSGSADRTVKCWLA 449
Query: 1249 KRGLALTSFSLH 1260
G + +F+ H
Sbjct: 450 DTGECVRTFTAH 461
Score = 57.2 bits (132), Expect = 4e-07
Identities = 63/264 (23%), Positives = 99/264 (37%), Gaps = 27/264 (10%)
Query: 980 LGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLAD 1039
L ASG + V T+R L GH ++T S D T+ W +
Sbjct: 216 LRASGAEKCAVVTLCYPTYRRGNRLGGHESYVTFCQLEDEAAFTCSA--DCTIRRWDVLT 273
Query: 1040 NSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGP-------- 1091
Y+GH+S + +L+ ++ + SS R VW VD G + G
Sbjct: 274 GQCLQVYRGHTSIVNRILVANN--QLFSSSYDRTARVWSVDKGQMSREFRGHRNCVLTLA 331
Query: 1092 -SASIDV--TLNMKYA------VLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
SA D+ T + A V D + ++W +A G + R H + C L
Sbjct: 332 YSAPWDLPSTPCAEEAAAGGLLVTGSTDGTAKVWQVASGCCHQTLR---GHTGAVLCLVL 388
Query: 1143 TADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLI 1202
TGS D +++ W + G+ +V H V C + + N+ V SGS D +
Sbjct: 389 DTPGHTAFTGSTDATIRAWDILSGEQLRVFREHRGSVIC--LELVNRL-VYSGSADRTVK 445
Query: 1203 VWDINTXXXXXXXXXXXXKVTCVK 1226
W +T V+ +K
Sbjct: 446 CWLADTGECVRTFTAHRRNVSALK 469
>AJ243005-1|CAB55581.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 75.4 bits (177), Expect = 1e-12
Identities = 95/460 (20%), Positives = 176/460 (38%), Gaps = 37/460 (8%)
Query: 828 TDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRV--AVGCADQRI 885
TDD F+ T D ++ + +TG +H H +V C + S + A G +D +
Sbjct: 667 TDDR-FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFL 725
Query: 886 YLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQM 945
L+ L+ + T LLA S + L + T
Sbjct: 726 KLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLA---------SCSADGTLKLWDATSAN 776
Query: 946 KRRQTKSTTNITLLQAEQSDL-IPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATL 1004
+R+ L+ Q D+ + + C S DG A+ + +W +
Sbjct: 777 ERKSINVKQFFLNLEDPQGDMEVIVKCCSWSADGAR-IMVAAKNKIFLWNTDSRSKVTDC 835
Query: 1005 NGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQ---LADNSPSLTYKGHSSAIQTLLMMSD 1061
GH+ + V FSP+ L+ S+D+T+ +W+ + NS + + Q +M
Sbjct: 836 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVM-- 893
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGG 1121
++ D R + + +G + + + ++ +++Y D + ++ I L
Sbjct: 894 ---VLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELV-- 948
Query: 1122 DNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTC 1181
N+ + H + + TAD + +++ S D ++VW K L GH + T
Sbjct: 949 -NNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCI-FLRGHQE--TV 1004
Query: 1182 VAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDK 1241
+ ++++S S+D + VW+I T V ++ D T S + DK
Sbjct: 1005 KDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADK 1064
Query: 1242 TLIIWETKRGLALTSFSLHVPLLGFQITSDCARVVVHLLD 1281
T IW SF L +PL + + C R +D
Sbjct: 1065 TAKIW---------SFDLLLPLHELRGHNGCVRCSAFSVD 1095
Score = 63.3 bits (147), Expect = 6e-09
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 1/117 (0%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKT 1190
+H + + C A + D + + T S+D +K+W G+L HS+ V C + ++
Sbjct: 655 AHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHL 714
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+ +GS DC L +WD+N V + + D + SC+ D TL +W+
Sbjct: 715 LLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 53.6 bits (123), Expect = 5e-06
Identities = 42/202 (20%), Positives = 91/202 (45%), Gaps = 5/202 (2%)
Query: 697 ILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGD 756
+ C C++ QY+ G E+ ++ + +L + +H V + + +IS D
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 757 DSAVIITSL-VDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLST 815
D+ + + + +D + L H+ +V +++++ + ++ S DGTV WN+
Sbjct: 981 DAEIQVWNWQLDKCIF--LRGHQETVKDFRLLKNSRL-LSWSFDGTVKVWNIITGNKEKD 1037
Query: 816 -VTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSS 874
V + D++ D + D + +F LH L+ H V+C + DS+
Sbjct: 1038 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST 1097
Query: 875 RVAVGCADQRIYLYSLHSAQLL 896
+A G + I ++++ + +LL
Sbjct: 1098 LLATGDDNGEIRIWNVSNGELL 1119
Score = 52.0 bits (119), Expect = 2e-05
Identities = 44/205 (21%), Positives = 86/205 (41%), Gaps = 12/205 (5%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC +S Q A G G + + +L +R+ + H + + F+ + ++S S+
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSG-----I 1083
D + VW + + +GH ++ ++ + R +S V VW + +G
Sbjct: 981 DAEIQVWNWQLDK-CIFLRGHQETVKDFRLLKNSR-LLSWSFDGTVKVWNIITGNKEKDF 1038
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
V H T S D++ + + D + +IWS D H + C A +
Sbjct: 1039 VCHQGT--VLSCDISHDATKFSSTSADKTAKIWSF---DLLLPLHELRGHNGCVRCSAFS 1093
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKL 1168
DS + TG + +++W + G+L
Sbjct: 1094 VDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 49.6 bits (113), Expect = 8e-05
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 10/142 (7%)
Query: 674 GDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKIL 733
G ++W+I++ +K F H G++L ++ ++ + S D + +W L ++
Sbjct: 1022 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1081
Query: 734 EHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALV---TKLDH-----HRGSVTSVK 785
H V C A V+ +L+ +G D+ + I ++ +G L+ L H G VT +
Sbjct: 1082 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1141
Query: 786 VIQDGNIFITGSQDGTVCTWNV 807
DG + I S G + WNV
Sbjct: 1142 FSPDGKMLI--SAGGYIKWWNV 1161
Score = 44.0 bits (99), Expect = 0.004
Identities = 33/146 (22%), Positives = 58/146 (39%), Gaps = 4/146 (2%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
GQ + + Q++ + K+ K H +LC + + +++ T S D V +W+
Sbjct: 627 GQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNS 686
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRS---LVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
T + EH V C N S L+ +G D + + L + H S
Sbjct: 687 MTGELVHTYDEHSEQVNC-CHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNS 745
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWN 806
V + D + + S DGT+ W+
Sbjct: 746 VNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 42.3 bits (95), Expect = 0.012
Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 9/147 (6%)
Query: 988 GLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYK 1047
G V+VW + T + H G + S + S S D+T +W P +
Sbjct: 1022 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1081
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH---------SATGPSASIDVT 1098
GH+ ++ D + D + +W V +G +LH +AT D+
Sbjct: 1082 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1141
Query: 1099 LNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+ +L ++ W++ G++S+
Sbjct: 1142 FSPDGKMLISAGGYIKWWNVVTGESSQ 1168
Score = 41.9 bits (94), Expect = 0.016
Identities = 58/308 (18%), Positives = 125/308 (40%), Gaps = 46/308 (14%)
Query: 951 KSTTNIT-LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIG 1009
K+ TN++ L+ +D + +C S DGQ AS A ++V++ T + H
Sbjct: 601 KNITNLSRLVVRPHTDAVYHACF--SEDGQRIASCGADKTLQVFKAETGEKLLEIKAHED 658
Query: 1010 HITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSD 1069
+ C FS ++ + + S D+ V +W TY HS + + + +
Sbjct: 659 EVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLAT 718
Query: 1070 RARN--VHVWLVDSGIVLHSATGPSASID---VTLNMKYAVLSDGDNSVRIWSLAGGDNS 1124
+ + + +W ++ ++ G + S++ + + K D ++++W S
Sbjct: 719 GSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDA----TS 774
Query: 1125 EDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV--WKLDGGKLSQVLVGHSDIVTCV 1182
+ R+S++ + F L + G M++ +K W DG + +
Sbjct: 775 ANERKSIN----VKQFFLNLEDPQ---GDMEVIVKCCSWSADGAR--------------I 813
Query: 1183 AVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKT 1242
V+ NK + +W+ ++ V V + DG+ ++ ++D+T
Sbjct: 814 MVAAKNK-----------IFLWNTDSRSKVTDCRGHLSWVHGVMFSPDGSSFLTSSDDQT 862
Query: 1243 LIIWETKR 1250
+ +WETK+
Sbjct: 863 IRLWETKK 870
Score = 41.1 bits (92), Expect = 0.028
Identities = 40/199 (20%), Positives = 79/199 (39%), Gaps = 7/199 (3%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
L+P Q++ G ++ +++N + H ++ + T + + L++ S+D +
Sbjct: 926 LSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQ 985
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
VW+ K L + ++ S ++S D V + +++ G H+G
Sbjct: 986 VWNWQ--LDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1043
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV---TAGVPIHIFDVTDDNVFLLT 836
+V S + D F + S D T W+ + L + V F V D+ L T
Sbjct: 1044 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSV--DSTLLAT 1101
Query: 837 LQGDNELHLRTFITGTYLH 855
+ E+ + G LH
Sbjct: 1102 GDDNGEIRIWNVSNGELLH 1120
Score = 35.1 bits (77), Expect = 1.9
Identities = 26/117 (22%), Positives = 47/117 (40%), Gaps = 2/117 (1%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ ++ C + + Q + + D ++ V+ T +I H VLC A + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
+ D V I + + G LV D H V + + TGS D + W++
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
>AF208838-1|AAL34973.1| 410|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 410
Score = 74.9 bits (176), Expect = 2e-12
Identities = 64/279 (22%), Positives = 116/279 (41%), Gaps = 25/279 (8%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR 1063
L+GH +T V F P +++S SED T+ VW T KGH+ ++Q + G+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 163
Query: 1064 --RAMSSDRARNVHVWLVDSGI-VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAG 1120
+ S+D + + I +H +S+ + N + V + D ++++W +
Sbjct: 164 LLASCSADMTIKLRDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
Query: 1121 GDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVT 1180
G + H E + D + + S D +++VW + + L H +V
Sbjct: 224 G---YCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 280
Query: 1181 CVA-------VSITNKTQ------------VVSGSWDCNLIVWDINTXXXXXXXXXXXXK 1221
C++ SI+ T ++SGS D + +WD++T
Sbjct: 281 CISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW 340
Query: 1222 VTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
V V G +SCA+DKTL +W+ K + + + H
Sbjct: 341 VRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAH 379
Score = 73.7 bits (173), Expect = 4e-12
Identities = 62/283 (21%), Positives = 116/283 (40%), Gaps = 27/283 (9%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
++VW T + TL GH + ++F + L+ S S D T+ + T GH
Sbjct: 132 IKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLRDFQGFECIRTMHGH 191
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLS- 1107
+ ++ +M +G +S+ R + + +W V +G + + TG + V N +++
Sbjct: 192 DHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 251
Query: 1108 -DGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQH------------------ 1148
D +VR+W +A + + R H + C + +S +
Sbjct: 252 CSNDQTVRVWVVATKECKAELR---EHEHVVECISWAPESSYSSISEATGSETKKSGKPG 308
Query: 1149 --VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+++GS D ++K+W + G LVGH + V V K ++S + D L VWD
Sbjct: 309 PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKF-ILSCADDKTLRVWDY 367
Query: 1207 NTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
VT + V+ + D+T+ +WE +
Sbjct: 368 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
Score = 55.2 bits (127), Expect = 2e-06
Identities = 59/310 (19%), Positives = 114/310 (36%), Gaps = 12/310 (3%)
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNV- 832
L HR VT V ++ ++ S+D T+ W+ E T+ G + D++ D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK-GHTDSVQDISFDHSG 162
Query: 833 -FLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLH 891
L + D + LR F + + H V + + + D+ I ++ +
Sbjct: 163 KLLASCSADMTIKLRDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 892 SAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTK 951
+ ++T L+A+ N T+ + + + K R
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW-----VVATKECKAELREHEH 277
Query: 952 STTNITLL-QAEQSDLIPISCLEVSRDGQLGA---SGCARGLVRVWQLSTHRLQATLNGH 1007
I+ ++ S + + E + G+ G SG +++W +ST TL GH
Sbjct: 278 VVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGH 337
Query: 1008 IGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMS 1067
+ V F +LS ++D+T+ VW + T H + +L ++
Sbjct: 338 DNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVT 397
Query: 1068 SDRARNVHVW 1077
+ V VW
Sbjct: 398 GSVDQTVKVW 407
Score = 54.8 bits (126), Expect = 2e-06
Identities = 40/201 (19%), Positives = 82/201 (40%), Gaps = 2/201 (0%)
Query: 675 DPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE 734
DP+ W I + + GH + + +++ SED ++ VWD T + +
Sbjct: 90 DPKGW-IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKG 148
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H V ++ + L+ S D + + + + H +V+SV ++ +G+ +
Sbjct: 149 HTDSVQDISFDHSGKLLASCSADMTIKLRDFQGFECIRTMHGHDHNVSSVAIMPNGDHIV 208
Query: 795 TGSQDGTVCTWNVENFTLLSTVTAGVP-IHIFDVTDDNVFLLTLQGDNELHLRTFITGTY 853
+ S+D T+ W V+ + T T + + D + + D + + T
Sbjct: 209 SASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKEC 268
Query: 854 LHPLKRHKAKVKCFCVAHDSS 874
L+ H+ V+C A +SS
Sbjct: 269 KAELREHEHVVECISWAPESS 289
Score = 46.8 bits (106), Expect = 6e-04
Identities = 34/141 (24%), Positives = 56/141 (39%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+V A ++W + T KGH+ S+ + + L + S D ++ + D
Sbjct: 123 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLRDFQGF 182
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
+ H V VA + N ++S D + + + G V HR V V+
Sbjct: 183 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRP 242
Query: 787 IQDGNIFITGSQDGTVCTWNV 807
QDG + + S D TV W V
Sbjct: 243 NQDGTLIASCSNDQTVRVWVV 263
Score = 46.8 bits (106), Expect = 6e-04
Identities = 38/179 (21%), Positives = 71/179 (39%), Gaps = 20/179 (11%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
+ P+G H+V A ++W + + V TF GH + + ++ + + S D +V
Sbjct: 200 IMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVR 259
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRS--------------------LVISGGDDSA 759
VW + T K ++ EH V C++ S ++SG D
Sbjct: 260 VWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKT 319
Query: 760 VIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA 818
+ + + G + L H V V G ++ + D T+ W+ +N + T+ A
Sbjct: 320 IKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA 378
Score = 41.5 bits (93), Expect = 0.021
Identities = 26/98 (26%), Positives = 44/98 (44%)
Query: 708 YLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVD 767
+LL+GS D ++ +WD+ T ++ H V V ++S DD + + +
Sbjct: 310 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 369
Query: 768 GALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
+ L+ H VTS+ + +TGS D TV W
Sbjct: 370 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
>U02609-1|AAA18945.1| 519|Homo sapiens transducin-like protein
protein.
Length = 519
Score = 74.5 bits (175), Expect = 2e-12
Identities = 68/284 (23%), Positives = 114/284 (40%), Gaps = 16/284 (5%)
Query: 982 ASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPN--NLLVLSGSEDRTVVVWQLAD 1039
A+G G VRVW + H G G + V F P+ LL+ S + D + VW L D
Sbjct: 11 ATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQD 70
Query: 1040 NSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGI------VLHSATG--- 1090
S H SA+ +L +DG +SS R + +W + S V S
Sbjct: 71 RSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVL 130
Query: 1091 ----PSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
P + + V Y + + ++R+W A G + + +T L +
Sbjct: 131 LPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGQELTHCTLAHTA 190
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
V+T + D +L +++ +L + G+S+ V V + VV S L V+++
Sbjct: 191 GVVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFEL 250
Query: 1207 NTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
T V + V G + SCA+D+++ IW +
Sbjct: 251 QTSACQILHGHTDI-VLALDVFRKGWLFASCAKDQSVRIWRMNK 293
Score = 45.2 bits (102), Expect = 0.002
Identities = 48/207 (23%), Positives = 82/207 (39%), Gaps = 18/207 (8%)
Query: 706 SQYLLTGSEDTSVIVWDL--HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIIT 763
S L TG D +V VWD+ H + + ++ R L+ S D+A+ +
Sbjct: 7 STLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVW 66
Query: 764 SLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN------FTLLSTVT 817
SL D + + L H +VTS+ DG+ ++ +D W++++ + +V
Sbjct: 67 SLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVE 126
Query: 818 AGV-----PIHIFDVTDDNVFLLTLQGDNELHLRTFITG----TYLHPLKRHKAKVKCFC 868
A V P+ V ++ LT L + +G T P + C
Sbjct: 127 AAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGQELTHC-T 185
Query: 869 VAHDSSRVAVGCADQRIYLYSLHSAQL 895
+AH + V AD + LY S +L
Sbjct: 186 LAHTAGVVLTATADHNLLLYEARSLRL 212
Score = 39.9 bits (89), Expect = 0.066
Identities = 45/204 (22%), Positives = 88/204 (43%), Gaps = 21/204 (10%)
Query: 992 VWQLSTHRLQATLNGHIGHITCVTF-SPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
+++ + RLQ G+ + V F P + V+ S + V++L ++ + + GH+
Sbjct: 204 LYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQTSACQILH-GHT 262
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVD-SGIVLHSATGPSASIDV------TLNMKY 1103
+ L + G S + ++V +W ++ +G V+ A G + V L +
Sbjct: 263 DIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESF 322
Query: 1104 AVLSDGDNSVRIW----SLAGGDNSEDNRRSV--------SHAERITCFALTADSQHVVT 1151
V D +V++W +L + + DN + H + I A+ + + + T
Sbjct: 323 LVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAHTTQRCHDKDINSVAIAPNDKLLAT 382
Query: 1152 GSMDMSLKVWKLDGGKLSQVLVGH 1175
GS D + K+W L +L V GH
Sbjct: 383 GSQDRTAKLWALPQCQLLGVFSGH 406
Score = 35.9 bits (79), Expect = 1.1
Identities = 24/106 (22%), Positives = 44/106 (41%), Gaps = 2/106 (1%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLL--TGSEDTSVI 719
P+ L G ++W I+ + H F+G G + + + LL + + D ++
Sbjct: 5 PTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIR 64
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL 765
VW L + + H + V +A + ++S G D II L
Sbjct: 65 VWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDL 110
Score = 35.1 bits (77), Expect = 1.9
Identities = 25/108 (23%), Positives = 41/108 (37%), Gaps = 1/108 (0%)
Query: 1141 ALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSIT-NKTQVVSGSWDC 1199
A S + TG D +++VW + + G +V VA + + S + D
Sbjct: 2 AFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDA 61
Query: 1200 NLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+ VW + VT + + DG +S DK IIW+
Sbjct: 62 AIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWD 109
Score = 33.5 bits (73), Expect = 5.7
Identities = 16/46 (34%), Positives = 23/46 (50%)
Query: 1007 HIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSA 1052
H I V +PN+ L+ +GS+DRT +W L + GH A
Sbjct: 364 HDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRVA 409
Score = 33.1 bits (72), Expect = 7.5
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 692 GHSGSILCMCVTR-ESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
GH+ S+ +C +R + +L+TGS+D +V +W L + P+L A R
Sbjct: 305 GHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAHTTQR 362
>BC010080-1|AAH10080.1| 305|Homo sapiens WD repeat domain 61 protein.
Length = 305
Score = 74.5 bits (175), Expect = 2e-12
Identities = 70/270 (25%), Positives = 112/270 (41%), Gaps = 9/270 (3%)
Query: 983 SGCARGLVRVWQLSTHRL--QATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN 1040
+G LV+VW+ RL Q +L GH + V S + S S D + +W L +
Sbjct: 37 TGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENG 96
Query: 1041 SPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA---SIDV 1097
+ TL D + + V+++ V+SG +S SI
Sbjct: 97 KQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAY 156
Query: 1098 TLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMS 1157
+ + KY D + I+ +A G HA I + DSQ +VT S D
Sbjct: 157 SPDGKYLASGAIDGIINIFDIATGKLLHTLE---GHAMPIRSLTFSPDSQLLVTASDDGY 213
Query: 1158 LKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXX 1217
+K++ + L+ L GH+ V VA + T VS S D ++ VWD+ T
Sbjct: 214 IKIYDVQHANLAGTLSGHASWVLNVAFC-PDDTHFVSSSSDKSVKVWDVGTRTCVHTFFD 272
Query: 1218 XXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+V VK G+G+ VS +D+ + I++
Sbjct: 273 HQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302
Score = 66.1 bits (154), Expect = 9e-10
Identities = 34/119 (28%), Positives = 65/119 (54%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I + S DG+ ASG G++ ++ ++T +L TL GH I +TFSP++ L+++ S+
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASD 210
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHS 1087
D + ++ + + + T GH+S + + D +SS ++V VW V + +H+
Sbjct: 211 DGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHT 269
Score = 58.4 bits (135), Expect = 2e-07
Identities = 50/245 (20%), Positives = 110/245 (44%), Gaps = 5/245 (2%)
Query: 1019 NNLLVLSGSEDRTVVVWQLADNSPSLTY--KGHSSAIQTLLMMSDGRRAMSSDRARNVHV 1076
N+ V++GS D V VW+ D L + +GH + ++ + A SS ++ +
Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRL 90
Query: 1077 WLVDSGIVLHSA-TGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE 1135
W +++G + S GP + + + L+ G + ++ ++ G ++ + + +
Sbjct: 91 WDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKV-NIFGVESGKKEYSLDTRGK 149
Query: 1136 RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSG 1195
I A + D +++ +G++D + ++ + GKL L GH+ + + S ++ +V+
Sbjct: 150 FILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQL-LVTA 208
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALT 1255
S D + ++D+ V V D T VS + DK++ +W+ +
Sbjct: 209 SDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVH 268
Query: 1256 SFSLH 1260
+F H
Sbjct: 269 TFFDH 273
Score = 56.4 bits (130), Expect = 7e-07
Identities = 29/120 (24%), Positives = 56/120 (46%)
Query: 958 LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFS 1017
LL + +PI L S D QL + G ++++ + L TL+GH + V F
Sbjct: 182 LLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFC 241
Query: 1018 PNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
P++ +S S D++V VW + + T+ H + + +G + +S + +H++
Sbjct: 242 PDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIY 301
Score = 54.4 bits (125), Expect = 3e-06
Identities = 43/214 (20%), Positives = 93/214 (43%), Gaps = 3/214 (1%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
+LW + + ++ + + + +SQYL TG+ V ++ + + + +
Sbjct: 89 RLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRG 148
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
+L +A + + SG D + I + G L+ L+ H + S+ D + +T
Sbjct: 149 KFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTA 208
Query: 797 SQDGTVCTWNVENFTLLSTVT--AGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYL 854
S DG + ++V++ L T++ A +++ DD F ++ D + + T T +
Sbjct: 209 SDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHF-VSSSSDKSVKVWDVGTRTCV 267
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
H H+ +V + S++ DQ I++Y
Sbjct: 268 HTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIY 301
Score = 50.4 bits (115), Expect = 5e-05
Identities = 45/237 (18%), Positives = 98/237 (41%), Gaps = 7/237 (2%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRT 1031
+++S + AS +R+W L + +++ + FSP++ + +G+
Sbjct: 70 VDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGK 129
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG- 1090
V ++ + + I ++ DG+ S ++++ + +G +LH+ G
Sbjct: 130 VNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGH 189
Query: 1091 --PSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQH 1148
P S+ + + + V + D ++I+ + ++ HA + A D H
Sbjct: 190 AMPIRSLTFSPDSQLLVTASDDGYIKIYDV---QHANLAGTLSGHASWVLNVAFCPDDTH 246
Query: 1149 VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
V+ S D S+KVW + H D V V + N +++VS D + ++D
Sbjct: 247 FVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYN-GNGSKIVSVGDDQEIHIYD 302
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/139 (23%), Positives = 64/139 (46%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+P G++L G ++ I + +HT +GH+ I + + +SQ L+T S+D + +
Sbjct: 157 SPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKI 216
Query: 721 WDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
+D+ + + H + VL VA + + +S D +V + + V H+
Sbjct: 217 YDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQ 276
Query: 781 VTSVKVIQDGNIFITGSQD 799
V VK +G+ ++ D
Sbjct: 277 VWGVKYNGNGSKIVSVGDD 295
Score = 48.8 bits (111), Expect = 1e-04
Identities = 30/107 (28%), Positives = 48/107 (44%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R L +P Q LV A G +++ + + T GH+ +L + + + ++ S D
Sbjct: 194 RSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSD 253
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVII 762
SV VWD+ T +H V V N S ++S GDD + I
Sbjct: 254 KSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHI 300
Score = 44.4 bits (100), Expect = 0.003
Identities = 33/164 (20%), Positives = 76/164 (46%), Gaps = 5/164 (3%)
Query: 960 QAEQSDLIPISC--LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFS 1017
Q + D P+ L S D Q A+G G V ++ + + + + +L+ I + +S
Sbjct: 98 QIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYS 157
Query: 1018 PNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
P+ + SG+ D + ++ +A T +GH+ I++L D + +++ + ++
Sbjct: 158 PDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIY 217
Query: 1078 LVDSGIVLHSATGPSA---SIDVTLNMKYAVLSDGDNSVRIWSL 1118
V + + +G ++ ++ + + V S D SV++W +
Sbjct: 218 DVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDV 261
Score = 37.1 bits (82), Expect = 0.46
Identities = 36/211 (17%), Positives = 76/211 (36%), Gaps = 1/211 (0%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
+ +GH ++ + ++ + S D + +WDL I +A +
Sbjct: 59 SLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDS 118
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
+ +G V I + G LD + S+ DG +G+ DG + +++
Sbjct: 119 QYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIA 178
Query: 809 NFTLLSTVTA-GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCF 867
LL T+ +PI + D+ L+T D + + L H + V
Sbjct: 179 TGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNV 238
Query: 868 CVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
D + +D+ + ++ + + + T
Sbjct: 239 AFCPDDTHFVSSSSDKSVKVWDVGTRTCVHT 269
Score = 35.9 bits (79), Expect = 1.1
Identities = 34/155 (21%), Positives = 65/155 (41%), Gaps = 3/155 (1%)
Query: 747 NRSLVISGGDDSAVIITSLVDGALVTK--LDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
N V++G D V + D L + L+ H+ V SV + I + S D +
Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRL 90
Query: 805 WNVENFTLLSTVTAG-VPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAK 863
W++EN + ++ AG V + D+ +L T ++++ +G + L
Sbjct: 91 WDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKF 150
Query: 864 VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ + D +A G D I ++ + + +LL T
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT 185
>AK024754-1|BAB14986.1| 305|Homo sapiens protein ( Homo sapiens cDNA:
FLJ21101 fis, clone CAS04682. ).
Length = 305
Score = 74.5 bits (175), Expect = 2e-12
Identities = 70/270 (25%), Positives = 112/270 (41%), Gaps = 9/270 (3%)
Query: 983 SGCARGLVRVWQLSTHRL--QATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN 1040
+G LV+VW+ RL Q +L GH + V S + S S D + +W L +
Sbjct: 37 TGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENG 96
Query: 1041 SPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA---SIDV 1097
+ TL D + + V+++ V+SG +S SI
Sbjct: 97 KQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAY 156
Query: 1098 TLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMS 1157
+ + KY D + I+ +A G HA I + DSQ +VT S D
Sbjct: 157 SPDGKYLASGAIDGIINIFDIATGKLLHTLE---GHAMPIRSLTFSPDSQLLVTASDDGY 213
Query: 1158 LKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXX 1217
+K++ + L+ L GH+ V VA + T VS S D ++ VWD+ T
Sbjct: 214 IKIYDVQHANLAGTLSGHASWVLNVAFC-PDDTHFVSSSSDKSVKVWDVGTRTCVHTFFD 272
Query: 1218 XXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+V VK G+G+ VS +D+ + I++
Sbjct: 273 HQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302
Score = 66.1 bits (154), Expect = 9e-10
Identities = 34/119 (28%), Positives = 65/119 (54%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I + S DG+ ASG G++ ++ ++T +L TL GH I +TFSP++ L+++ S+
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASD 210
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHS 1087
D + ++ + + + T GH+S + + D +SS ++V VW V + +H+
Sbjct: 211 DGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHT 269
Score = 58.4 bits (135), Expect = 2e-07
Identities = 50/245 (20%), Positives = 110/245 (44%), Gaps = 5/245 (2%)
Query: 1019 NNLLVLSGSEDRTVVVWQLADNSPSLTY--KGHSSAIQTLLMMSDGRRAMSSDRARNVHV 1076
N+ V++GS D V VW+ D L + +GH + ++ + A SS ++ +
Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRL 90
Query: 1077 WLVDSGIVLHSA-TGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE 1135
W +++G + S GP + + + L+ G + ++ ++ G ++ + + +
Sbjct: 91 WDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKV-NIFGVESGKKEYSLDTRGK 149
Query: 1136 RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSG 1195
I A + D +++ +G++D + ++ + GKL L GH+ + + S ++ +V+
Sbjct: 150 FILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQL-LVTA 208
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALT 1255
S D + ++D+ V V D T VS + DK++ +W+ +
Sbjct: 209 SDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVH 268
Query: 1256 SFSLH 1260
+F H
Sbjct: 269 TFFDH 273
Score = 56.4 bits (130), Expect = 7e-07
Identities = 29/120 (24%), Positives = 56/120 (46%)
Query: 958 LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFS 1017
LL + +PI L S D QL + G ++++ + L TL+GH + V F
Sbjct: 182 LLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFC 241
Query: 1018 PNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
P++ +S S D++V VW + + T+ H + + +G + +S + +H++
Sbjct: 242 PDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIY 301
Score = 54.4 bits (125), Expect = 3e-06
Identities = 43/214 (20%), Positives = 93/214 (43%), Gaps = 3/214 (1%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
+LW + + ++ + + + +SQYL TG+ V ++ + + + +
Sbjct: 89 RLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRG 148
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
+L +A + + SG D + I + G L+ L+ H + S+ D + +T
Sbjct: 149 KFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTA 208
Query: 797 SQDGTVCTWNVENFTLLSTVT--AGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYL 854
S DG + ++V++ L T++ A +++ DD F ++ D + + T T +
Sbjct: 209 SDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHF-VSSSSDKSVKVWDVGTRTCV 267
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
H H+ +V + S++ DQ I++Y
Sbjct: 268 HTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIY 301
Score = 50.4 bits (115), Expect = 5e-05
Identities = 45/237 (18%), Positives = 98/237 (41%), Gaps = 7/237 (2%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRT 1031
+++S + AS +R+W L + +++ + FSP++ + +G+
Sbjct: 70 VDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGK 129
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG- 1090
V ++ + + I ++ DG+ S ++++ + +G +LH+ G
Sbjct: 130 VNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGH 189
Query: 1091 --PSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQH 1148
P S+ + + + V + D ++I+ + ++ HA + A D H
Sbjct: 190 AMPIRSLTFSPDSQLLVTASDDGYIKIYDV---QHANLAGTLSGHASWVLNVAFCPDDTH 246
Query: 1149 VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
V+ S D S+KVW + H D V V + N +++VS D + ++D
Sbjct: 247 FVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYN-GNGSKIVSVGDDQEIHIYD 302
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/139 (23%), Positives = 64/139 (46%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+P G++L G ++ I + +HT +GH+ I + + +SQ L+T S+D + +
Sbjct: 157 SPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKI 216
Query: 721 WDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
+D+ + + H + VL VA + + +S D +V + + V H+
Sbjct: 217 YDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQ 276
Query: 781 VTSVKVIQDGNIFITGSQD 799
V VK +G+ ++ D
Sbjct: 277 VWGVKYNGNGSKIVSVGDD 295
Score = 48.8 bits (111), Expect = 1e-04
Identities = 30/107 (28%), Positives = 48/107 (44%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R L +P Q LV A G +++ + + T GH+ +L + + + ++ S D
Sbjct: 194 RSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSD 253
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVII 762
SV VWD+ T +H V V N S ++S GDD + I
Sbjct: 254 KSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHI 300
Score = 44.4 bits (100), Expect = 0.003
Identities = 33/164 (20%), Positives = 76/164 (46%), Gaps = 5/164 (3%)
Query: 960 QAEQSDLIPISC--LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFS 1017
Q + D P+ L S D Q A+G G V ++ + + + + +L+ I + +S
Sbjct: 98 QIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYS 157
Query: 1018 PNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
P+ + SG+ D + ++ +A T +GH+ I++L D + +++ + ++
Sbjct: 158 PDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIY 217
Query: 1078 LVDSGIVLHSATGPSA---SIDVTLNMKYAVLSDGDNSVRIWSL 1118
V + + +G ++ ++ + + V S D SV++W +
Sbjct: 218 DVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDV 261
Score = 37.1 bits (82), Expect = 0.46
Identities = 36/211 (17%), Positives = 76/211 (36%), Gaps = 1/211 (0%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
+ +GH ++ + ++ + S D + +WDL I +A +
Sbjct: 59 SLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDS 118
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
+ +G V I + G LD + S+ DG +G+ DG + +++
Sbjct: 119 QYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIA 178
Query: 809 NFTLLSTVTA-GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCF 867
LL T+ +PI + D+ L+T D + + L H + V
Sbjct: 179 TGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNV 238
Query: 868 CVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
D + +D+ + ++ + + + T
Sbjct: 239 AFCPDDTHFVSSSSDKSVKVWDVGTRTCVHT 269
Score = 35.9 bits (79), Expect = 1.1
Identities = 34/155 (21%), Positives = 65/155 (41%), Gaps = 3/155 (1%)
Query: 747 NRSLVISGGDDSAVIITSLVDGALVTK--LDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
N V++G D V + D L + L+ H+ V SV + I + S D +
Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRL 90
Query: 805 WNVENFTLLSTVTAG-VPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAK 863
W++EN + ++ AG V + D+ +L T ++++ +G + L
Sbjct: 91 WDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKF 150
Query: 864 VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ + D +A G D I ++ + + +LL T
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT 185
>AF309553-1|AAG31639.1| 305|Homo sapiens meiotic recombination
protein REC14 protein.
Length = 305
Score = 74.5 bits (175), Expect = 2e-12
Identities = 70/270 (25%), Positives = 112/270 (41%), Gaps = 9/270 (3%)
Query: 983 SGCARGLVRVWQLSTHRL--QATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN 1040
+G LV+VW+ RL Q +L GH + V S + S S D + +W L +
Sbjct: 37 TGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENG 96
Query: 1041 SPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA---SIDV 1097
+ TL D + + V+++ V+SG +S SI
Sbjct: 97 KQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAY 156
Query: 1098 TLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMS 1157
+ + KY D + I+ +A G HA I + DSQ +VT S D
Sbjct: 157 SPDGKYLASGAIDGIINIFDIATGKLLHTLE---GHAMPIRSLTFSPDSQLLVTASDDGY 213
Query: 1158 LKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXX 1217
+K++ + L+ L GH+ V VA + T VS S D ++ VWD+ T
Sbjct: 214 IKIYDVQHANLAGTLSGHASWVLNVAFC-PDDTHFVSSSSDKSVKVWDVGTRTCVHTFFD 272
Query: 1218 XXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+V VK G+G+ VS +D+ + I++
Sbjct: 273 HQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302
Score = 66.1 bits (154), Expect = 9e-10
Identities = 34/119 (28%), Positives = 65/119 (54%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I + S DG+ ASG G++ ++ ++T +L TL GH I +TFSP++ L+++ S+
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASD 210
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHS 1087
D + ++ + + + T GH+S + + D +SS ++V VW V + +H+
Sbjct: 211 DGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHT 269
Score = 58.4 bits (135), Expect = 2e-07
Identities = 50/245 (20%), Positives = 110/245 (44%), Gaps = 5/245 (2%)
Query: 1019 NNLLVLSGSEDRTVVVWQLADNSPSLTY--KGHSSAIQTLLMMSDGRRAMSSDRARNVHV 1076
N+ V++GS D V VW+ D L + +GH + ++ + A SS ++ +
Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRL 90
Query: 1077 WLVDSGIVLHSA-TGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE 1135
W +++G + S GP + + + L+ G + ++ ++ G ++ + + +
Sbjct: 91 WDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKV-NIFGVESGKKEYSLDTRGK 149
Query: 1136 RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSG 1195
I A + D +++ +G++D + ++ + GKL L GH+ + + S ++ +V+
Sbjct: 150 FILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQL-LVTA 208
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALT 1255
S D + ++D+ V V D T VS + DK++ +W+ +
Sbjct: 209 SDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVH 268
Query: 1256 SFSLH 1260
+F H
Sbjct: 269 TFFDH 273
Score = 56.4 bits (130), Expect = 7e-07
Identities = 29/120 (24%), Positives = 56/120 (46%)
Query: 958 LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFS 1017
LL + +PI L S D QL + G ++++ + L TL+GH + V F
Sbjct: 182 LLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFC 241
Query: 1018 PNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
P++ +S S D++V VW + + T+ H + + +G + +S + +H++
Sbjct: 242 PDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIY 301
Score = 54.4 bits (125), Expect = 3e-06
Identities = 43/214 (20%), Positives = 93/214 (43%), Gaps = 3/214 (1%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
+LW + + ++ + + + +SQYL TG+ V ++ + + + +
Sbjct: 89 RLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRG 148
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
+L +A + + SG D + I + G L+ L+ H + S+ D + +T
Sbjct: 149 KFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTA 208
Query: 797 SQDGTVCTWNVENFTLLSTVT--AGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYL 854
S DG + ++V++ L T++ A +++ DD F ++ D + + T T +
Sbjct: 209 SDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHF-VSSSSDKSVKVWDVGTRTCV 267
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
H H+ +V + S++ DQ I++Y
Sbjct: 268 HTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIY 301
Score = 50.4 bits (115), Expect = 5e-05
Identities = 45/237 (18%), Positives = 98/237 (41%), Gaps = 7/237 (2%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRT 1031
+++S + AS +R+W L + +++ + FSP++ + +G+
Sbjct: 70 VDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGK 129
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG- 1090
V ++ + + I ++ DG+ S ++++ + +G +LH+ G
Sbjct: 130 VNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGH 189
Query: 1091 --PSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQH 1148
P S+ + + + V + D ++I+ + ++ HA + A D H
Sbjct: 190 AMPIRSLTFSPDSQLLVTASDDGYIKIYDV---QHANLAGTLSGHASWVLNVAFCPDDTH 246
Query: 1149 VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
V+ S D S+KVW + H D V V + N +++VS D + ++D
Sbjct: 247 FVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYN-GNGSKIVSVGDDQEIHIYD 302
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/139 (23%), Positives = 64/139 (46%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+P G++L G ++ I + +HT +GH+ I + + +SQ L+T S+D + +
Sbjct: 157 SPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKI 216
Query: 721 WDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
+D+ + + H + VL VA + + +S D +V + + V H+
Sbjct: 217 YDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQ 276
Query: 781 VTSVKVIQDGNIFITGSQD 799
V VK +G+ ++ D
Sbjct: 277 VWGVKYNGNGSKIVSVGDD 295
Score = 48.8 bits (111), Expect = 1e-04
Identities = 30/107 (28%), Positives = 48/107 (44%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R L +P Q LV A G +++ + + T GH+ +L + + + ++ S D
Sbjct: 194 RSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSD 253
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVII 762
SV VWD+ T +H V V N S ++S GDD + I
Sbjct: 254 KSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHI 300
Score = 44.4 bits (100), Expect = 0.003
Identities = 33/164 (20%), Positives = 76/164 (46%), Gaps = 5/164 (3%)
Query: 960 QAEQSDLIPISC--LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFS 1017
Q + D P+ L S D Q A+G G V ++ + + + + +L+ I + +S
Sbjct: 98 QIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYS 157
Query: 1018 PNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
P+ + SG+ D + ++ +A T +GH+ I++L D + +++ + ++
Sbjct: 158 PDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIY 217
Query: 1078 LVDSGIVLHSATGPSA---SIDVTLNMKYAVLSDGDNSVRIWSL 1118
V + + +G ++ ++ + + V S D SV++W +
Sbjct: 218 DVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDV 261
Score = 37.1 bits (82), Expect = 0.46
Identities = 36/211 (17%), Positives = 76/211 (36%), Gaps = 1/211 (0%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
+ +GH ++ + ++ + S D + +WDL I +A +
Sbjct: 59 SLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDS 118
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
+ +G V I + G LD + S+ DG +G+ DG + +++
Sbjct: 119 QYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIA 178
Query: 809 NFTLLSTVTA-GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCF 867
LL T+ +PI + D+ L+T D + + L H + V
Sbjct: 179 TGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNV 238
Query: 868 CVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
D + +D+ + ++ + + + T
Sbjct: 239 AFCPDDTHFVSSSSDKSVKVWDVGTRTCVHT 269
Score = 35.9 bits (79), Expect = 1.1
Identities = 34/155 (21%), Positives = 65/155 (41%), Gaps = 3/155 (1%)
Query: 747 NRSLVISGGDDSAVIITSLVDGALVTK--LDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
N V++G D V + D L + L+ H+ V SV + I + S D +
Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRL 90
Query: 805 WNVENFTLLSTVTAG-VPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAK 863
W++EN + ++ AG V + D+ +L T ++++ +G + L
Sbjct: 91 WDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKF 150
Query: 864 VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ + D +A G D I ++ + + +LL T
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT 185
>AF100786-1|AAP97225.1| 305|Homo sapiens G protein beta subunit-like
protein protein.
Length = 305
Score = 74.5 bits (175), Expect = 2e-12
Identities = 70/270 (25%), Positives = 112/270 (41%), Gaps = 9/270 (3%)
Query: 983 SGCARGLVRVWQLSTHRL--QATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN 1040
+G LV+VW+ RL Q +L GH + V S + S S D + +W L +
Sbjct: 37 TGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENG 96
Query: 1041 SPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA---SIDV 1097
+ TL D + + V+++ V+SG +S SI
Sbjct: 97 KQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAY 156
Query: 1098 TLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMS 1157
+ + KY D + I+ +A G HA I + DSQ +VT S D
Sbjct: 157 SPDGKYLASGAIDGIINIFDIATGKLLHTLE---GHAMPIRSLTFSPDSQLLVTASDDGY 213
Query: 1158 LKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXX 1217
+K++ + L+ L GH+ V VA + T VS S D ++ VWD+ T
Sbjct: 214 IKIYDVQHANLAGTLSGHASWVLNVAFC-PDDTHFVSSSSDKSVKVWDVGTRTCVHTFFD 272
Query: 1218 XXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+V VK G+G+ VS +D+ + I++
Sbjct: 273 HQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302
Score = 66.1 bits (154), Expect = 9e-10
Identities = 34/119 (28%), Positives = 65/119 (54%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I + S DG+ ASG G++ ++ ++T +L TL GH I +TFSP++ L+++ S+
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASD 210
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHS 1087
D + ++ + + + T GH+S + + D +SS ++V VW V + +H+
Sbjct: 211 DGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHT 269
Score = 58.4 bits (135), Expect = 2e-07
Identities = 50/245 (20%), Positives = 110/245 (44%), Gaps = 5/245 (2%)
Query: 1019 NNLLVLSGSEDRTVVVWQLADNSPSLTY--KGHSSAIQTLLMMSDGRRAMSSDRARNVHV 1076
N+ V++GS D V VW+ D L + +GH + ++ + A SS ++ +
Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRL 90
Query: 1077 WLVDSGIVLHSA-TGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE 1135
W +++G + S GP + + + L+ G + ++ ++ G ++ + + +
Sbjct: 91 WDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKV-NIFGVESGKKEYSLDTRGK 149
Query: 1136 RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSG 1195
I A + D +++ +G++D + ++ + GKL L GH+ + + S ++ +V+
Sbjct: 150 FILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQL-LVTA 208
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALT 1255
S D + ++D+ V V D T VS + DK++ +W+ +
Sbjct: 209 SDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVH 268
Query: 1256 SFSLH 1260
+F H
Sbjct: 269 TFFDH 273
Score = 56.4 bits (130), Expect = 7e-07
Identities = 29/120 (24%), Positives = 56/120 (46%)
Query: 958 LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFS 1017
LL + +PI L S D QL + G ++++ + L TL+GH + V F
Sbjct: 182 LLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFC 241
Query: 1018 PNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
P++ +S S D++V VW + + T+ H + + +G + +S + +H++
Sbjct: 242 PDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIY 301
Score = 54.4 bits (125), Expect = 3e-06
Identities = 43/214 (20%), Positives = 93/214 (43%), Gaps = 3/214 (1%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
+LW + + ++ + + + +SQYL TG+ V ++ + + + +
Sbjct: 89 RLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRG 148
Query: 737 APVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG 796
+L +A + + SG D + I + G L+ L+ H + S+ D + +T
Sbjct: 149 KFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTA 208
Query: 797 SQDGTVCTWNVENFTLLSTVT--AGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYL 854
S DG + ++V++ L T++ A +++ DD F ++ D + + T T +
Sbjct: 209 SDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHF-VSSSSDKSVKVWDVGTRTCV 267
Query: 855 HPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
H H+ +V + S++ DQ I++Y
Sbjct: 268 HTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIY 301
Score = 50.4 bits (115), Expect = 5e-05
Identities = 45/237 (18%), Positives = 98/237 (41%), Gaps = 7/237 (2%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRT 1031
+++S + AS +R+W L + +++ + FSP++ + +G+
Sbjct: 70 VDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGK 129
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG- 1090
V ++ + + I ++ DG+ S ++++ + +G +LH+ G
Sbjct: 130 VNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGH 189
Query: 1091 --PSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQH 1148
P S+ + + + V + D ++I+ + ++ HA + A D H
Sbjct: 190 AMPIRSLTFSPDSQLLVTASDDGYIKIYDV---QHANLAGTLSGHASWVLNVAFCPDDTH 246
Query: 1149 VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
V+ S D S+KVW + H D V V + N +++VS D + ++D
Sbjct: 247 FVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYN-GNGSKIVSVGDDQEIHIYD 302
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/139 (23%), Positives = 64/139 (46%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+P G++L G ++ I + +HT +GH+ I + + +SQ L+T S+D + +
Sbjct: 157 SPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKI 216
Query: 721 WDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
+D+ + + H + VL VA + + +S D +V + + V H+
Sbjct: 217 YDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQ 276
Query: 781 VTSVKVIQDGNIFITGSQD 799
V VK +G+ ++ D
Sbjct: 277 VWGVKYNGNGSKIVSVGDD 295
Score = 48.8 bits (111), Expect = 1e-04
Identities = 30/107 (28%), Positives = 48/107 (44%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R L +P Q LV A G +++ + + T GH+ +L + + + ++ S D
Sbjct: 194 RSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSD 253
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVII 762
SV VWD+ T +H V V N S ++S GDD + I
Sbjct: 254 KSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHI 300
Score = 44.4 bits (100), Expect = 0.003
Identities = 33/164 (20%), Positives = 76/164 (46%), Gaps = 5/164 (3%)
Query: 960 QAEQSDLIPISC--LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFS 1017
Q + D P+ L S D Q A+G G V ++ + + + + +L+ I + +S
Sbjct: 98 QIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYS 157
Query: 1018 PNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
P+ + SG+ D + ++ +A T +GH+ I++L D + +++ + ++
Sbjct: 158 PDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIY 217
Query: 1078 LVDSGIVLHSATGPSA---SIDVTLNMKYAVLSDGDNSVRIWSL 1118
V + + +G ++ ++ + + V S D SV++W +
Sbjct: 218 DVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDV 261
Score = 37.1 bits (82), Expect = 0.46
Identities = 36/211 (17%), Positives = 76/211 (36%), Gaps = 1/211 (0%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
+ +GH ++ + ++ + S D + +WDL I +A +
Sbjct: 59 SLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDS 118
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
+ +G V I + G LD + S+ DG +G+ DG + +++
Sbjct: 119 QYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIA 178
Query: 809 NFTLLSTVTA-GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCF 867
LL T+ +PI + D+ L+T D + + L H + V
Sbjct: 179 TGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNV 238
Query: 868 CVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
D + +D+ + ++ + + + T
Sbjct: 239 AFCPDDTHFVSSSSDKSVKVWDVGTRTCVHT 269
Score = 35.9 bits (79), Expect = 1.1
Identities = 34/155 (21%), Positives = 65/155 (41%), Gaps = 3/155 (1%)
Query: 747 NRSLVISGGDDSAVIITSLVDGALVTK--LDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
N V++G D V + D L + L+ H+ V SV + I + S D +
Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRL 90
Query: 805 WNVENFTLLSTVTAG-VPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAK 863
W++EN + ++ AG V + D+ +L T ++++ +G + L
Sbjct: 91 WDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKF 150
Query: 864 VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ + D +A G D I ++ + + +LL T
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT 185
>EF011613-1|ABK41103.1| 513|Homo sapiens CDW3/SMU1 protein.
Length = 513
Score = 73.7 bits (173), Expect = 4e-12
Identities = 49/186 (26%), Positives = 86/186 (46%), Gaps = 9/186 (4%)
Query: 659 QLAPSGQHLVLAPSAGDPQLWH-----IMSNSKVHT---FKGHSGSILCMCVTRESQYLL 710
+ +P GQ+LV G ++W+ I + K F ++LCMC +R+++ L
Sbjct: 221 RFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLA 280
Query: 711 TGSEDTSVIVWDLHT-LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGA 769
TG++D + VW + + ++ H V C++ + S ++S D + I L G
Sbjct: 281 TGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGK 340
Query: 770 LVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTD 829
+ + H V QDG+ I+ S DGTV WN++ +T + D+T
Sbjct: 341 TLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITV 400
Query: 830 DNVFLL 835
++V LL
Sbjct: 401 NSVILL 406
Score = 68.5 bits (160), Expect = 2e-10
Identities = 56/230 (24%), Positives = 105/230 (45%), Gaps = 20/230 (8%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHR-LQATLNGHIGHITCVTFSPNNLLVLSGS 1027
+ C+ SRD ++ A+G G ++VW++ + + L+ H +TC++FS ++ +LS S
Sbjct: 267 VLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSAS 326
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHS 1087
D+T+ + L ++GHSS + DG +S+ V +W + + ++
Sbjct: 327 FDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNT 386
Query: 1088 --ATGPSASIDVTLNM--------KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAER- 1136
+ G +A D+T+N ++ V+ + N+V I ++ G RS S +R
Sbjct: 387 FKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQG-----QIVRSFSSGKRE 441
Query: 1137 ---ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVA 1183
C AL+ + + D L + GKL + L H V +A
Sbjct: 442 GGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIA 491
Score = 61.3 bits (142), Expect = 2e-08
Identities = 41/174 (23%), Positives = 73/174 (41%), Gaps = 7/174 (4%)
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHA-----ERITCFALTADSQHVVTGSMDM 1156
+Y V D + +W+ G +D + + + C + D++ + TG+ D
Sbjct: 227 QYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDG 286
Query: 1157 SLKVWKLDGGK-LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXX 1215
+KVWK+ G+ L + HS VTC++ S + +Q++S S+D + + + +
Sbjct: 287 KIKVWKIQSGQCLRRFERAHSKGVTCLSFS-KDSSQILSASFDQTIRIHGLKSGKTLKEF 345
Query: 1216 XXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLGFQIT 1269
V T DG +S + D T+ IW K +F G IT
Sbjct: 346 RGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDIT 399
Score = 56.4 bits (130), Expect = 7e-07
Identities = 34/162 (20%), Positives = 72/162 (44%), Gaps = 12/162 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHI--------GHITCVTFSPNN 1020
+ C S DGQ +G G + VW +T +++ L + C+ FS +
Sbjct: 217 VECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDT 276
Query: 1021 LLVLSGSEDRTVVVWQLADNSPSLTY-KGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLV 1079
++ +G++D + VW++ + + HS + L D + +S+ + + + +
Sbjct: 277 EMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGL 336
Query: 1080 DSGIVLHSATGPSASID---VTLNMKYAVLSDGDNSVRIWSL 1118
SG L G S+ ++ T + Y + + D +V+IW++
Sbjct: 337 KSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNM 378
Score = 50.4 bits (115), Expect = 5e-05
Identities = 36/133 (27%), Positives = 60/133 (45%), Gaps = 10/133 (7%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL--------VGHSDIVTCVAVSITN 1188
+ C + D Q++VTGS+D ++VW GK+ + L + D V C+ S +
Sbjct: 217 VECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFS-RD 275
Query: 1189 KTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-VTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+ +G+ D + VW I + K VTC+ + D + +S + D+T+ I
Sbjct: 276 TEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHG 335
Query: 1248 TKRGLALTSFSLH 1260
K G L F H
Sbjct: 336 LKSGKTLKEFRGH 348
Score = 46.8 bits (106), Expect = 6e-04
Identities = 38/194 (19%), Positives = 76/194 (39%), Gaps = 20/194 (10%)
Query: 987 RGLVRVWQLSTHRLQATLNGHI-----GHITCVTFSPNNLLVLSGSEDRTVVVWQLADNS 1041
RG V + + L+ HI H+ C FSP+ +++GS D + VW
Sbjct: 188 RGKAAVKDVEEEKFPTQLSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGK 247
Query: 1042 --PSLTYKGHSS------AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVL----HSAT 1089
L Y+ + A+ + D + + + VW + SG L + +
Sbjct: 248 IRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHS 307
Query: 1090 GPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHV 1149
+ + + + + D ++RI L G ++ R H+ + T D ++
Sbjct: 308 KGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFR---GHSSFVNEATFTQDGHYI 364
Query: 1150 VTGSMDMSLKVWKL 1163
++ S D ++K+W +
Sbjct: 365 ISASSDGTVKIWNM 378
Score = 39.5 bits (88), Expect = 0.087
Identities = 29/125 (23%), Positives = 56/125 (44%), Gaps = 11/125 (8%)
Query: 688 HTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIA---------P 738
H G + C + + QYL+TGS D + VW+ T ++ K L++ A
Sbjct: 208 HIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIR-KDLKYQAQDNFMMMDDA 266
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGNIFITGS 797
VLC+ + ++ +G D + + + G + + + H VT + +D + ++ S
Sbjct: 267 VLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSAS 326
Query: 798 QDGTV 802
D T+
Sbjct: 327 FDQTI 331
Score = 36.3 bits (80), Expect = 0.81
Identities = 30/130 (23%), Positives = 50/130 (38%), Gaps = 10/130 (7%)
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTD-------- 829
+ V + DG +TGS DG + WN + + + + D
Sbjct: 214 KSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFS 273
Query: 830 -DNVFLLTLQGDNELHLRTFITGTYLHPLKR-HKAKVKCFCVAHDSSRVAVGCADQRIYL 887
D L T D ++ + +G L +R H V C + DSS++ DQ I +
Sbjct: 274 RDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRI 333
Query: 888 YSLHSAQLLR 897
+ L S + L+
Sbjct: 334 HGLKSGKTLK 343
Score = 33.9 bits (74), Expect = 4.3
Identities = 34/152 (22%), Positives = 61/152 (40%), Gaps = 11/152 (7%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
G +++ A S G ++W++ + +TFK GS +T S LL + + V+
Sbjct: 361 GHYIISASSDGTVKIWNMKTTECSNTFKS-LGSTAGTDITVNSVILLPKNPEHFVVCNRS 419
Query: 724 HTLAVKT---KILEHIAP-------VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTK 773
+T+ + +I+ + +C A + G+D + S V G L
Sbjct: 420 NTVVIMNMQGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERT 479
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
L H V + N+ T S+DG + W
Sbjct: 480 LTVHEKDVIGIAHHPHQNLIATYSEDGLLKLW 511
>BC110654-1|AAI10655.1| 513|Homo sapiens smu-1 suppressor of mec-8
and unc-52 homolog (C. elegans) protein.
Length = 513
Score = 73.7 bits (173), Expect = 4e-12
Identities = 49/186 (26%), Positives = 86/186 (46%), Gaps = 9/186 (4%)
Query: 659 QLAPSGQHLVLAPSAGDPQLWH-----IMSNSKVHT---FKGHSGSILCMCVTRESQYLL 710
+ +P GQ+LV G ++W+ I + K F ++LCMC +R+++ L
Sbjct: 221 RFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLA 280
Query: 711 TGSEDTSVIVWDLHT-LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGA 769
TG++D + VW + + ++ H V C++ + S ++S D + I L G
Sbjct: 281 TGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGK 340
Query: 770 LVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTD 829
+ + H V QDG+ I+ S DGTV WN++ +T + D+T
Sbjct: 341 TLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITV 400
Query: 830 DNVFLL 835
++V LL
Sbjct: 401 NSVILL 406
Score = 69.3 bits (162), Expect = 9e-11
Identities = 60/251 (23%), Positives = 114/251 (45%), Gaps = 21/251 (8%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHR-LQATLNGHIGHITCVTFSPNNLLVLSGS 1027
+ C+ SRD ++ A+G G ++VW++ + + L+ H +TC++FS ++ +LS S
Sbjct: 267 VLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSAS 326
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHS 1087
D+T+ + L ++GHSS + DG +S+ V +W + + ++
Sbjct: 327 FDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNT 386
Query: 1088 --ATGPSASIDVTLNM--------KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAER- 1136
+ G +A D+T+N ++ V+ + N+V I ++ G RS S +R
Sbjct: 387 FKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQG-----QIVRSFSSGKRE 441
Query: 1137 ---ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVV 1193
C AL+ + + D L + GKL + L H V +A ++ +
Sbjct: 442 GGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIA-HHPHQNLIA 500
Query: 1194 SGSWDCNLIVW 1204
+ S D L +W
Sbjct: 501 TYSEDALLKLW 511
Score = 61.3 bits (142), Expect = 2e-08
Identities = 41/174 (23%), Positives = 73/174 (41%), Gaps = 7/174 (4%)
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHA-----ERITCFALTADSQHVVTGSMDM 1156
+Y V D + +W+ G +D + + + C + D++ + TG+ D
Sbjct: 227 QYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDG 286
Query: 1157 SLKVWKLDGGK-LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXX 1215
+KVWK+ G+ L + HS VTC++ S + +Q++S S+D + + + +
Sbjct: 287 KIKVWKIQSGQCLRRFERAHSKGVTCLSFS-KDSSQILSASFDQTIRIHGLKSGKTLKEF 345
Query: 1216 XXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLGFQIT 1269
V T DG +S + D T+ IW K +F G IT
Sbjct: 346 RGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDIT 399
Score = 56.4 bits (130), Expect = 7e-07
Identities = 34/162 (20%), Positives = 72/162 (44%), Gaps = 12/162 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHI--------GHITCVTFSPNN 1020
+ C S DGQ +G G + VW +T +++ L + C+ FS +
Sbjct: 217 VECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDT 276
Query: 1021 LLVLSGSEDRTVVVWQLADNSPSLTY-KGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLV 1079
++ +G++D + VW++ + + HS + L D + +S+ + + + +
Sbjct: 277 EMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGL 336
Query: 1080 DSGIVLHSATGPSASID---VTLNMKYAVLSDGDNSVRIWSL 1118
SG L G S+ ++ T + Y + + D +V+IW++
Sbjct: 337 KSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNM 378
Score = 50.4 bits (115), Expect = 5e-05
Identities = 36/133 (27%), Positives = 60/133 (45%), Gaps = 10/133 (7%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL--------VGHSDIVTCVAVSITN 1188
+ C + D Q++VTGS+D ++VW GK+ + L + D V C+ S +
Sbjct: 217 VECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFS-RD 275
Query: 1189 KTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-VTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+ +G+ D + VW I + K VTC+ + D + +S + D+T+ I
Sbjct: 276 TEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHG 335
Query: 1248 TKRGLALTSFSLH 1260
K G L F H
Sbjct: 336 LKSGKTLKEFRGH 348
Score = 46.8 bits (106), Expect = 6e-04
Identities = 38/194 (19%), Positives = 76/194 (39%), Gaps = 20/194 (10%)
Query: 987 RGLVRVWQLSTHRLQATLNGHI-----GHITCVTFSPNNLLVLSGSEDRTVVVWQLADNS 1041
RG V + + L+ HI H+ C FSP+ +++GS D + VW
Sbjct: 188 RGKAAVKDVEEEKFPTQLSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGK 247
Query: 1042 --PSLTYKGHSS------AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVL----HSAT 1089
L Y+ + A+ + D + + + VW + SG L + +
Sbjct: 248 IRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHS 307
Query: 1090 GPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHV 1149
+ + + + + D ++RI L G ++ R H+ + T D ++
Sbjct: 308 KGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFR---GHSSFVNEATFTQDGHYI 364
Query: 1150 VTGSMDMSLKVWKL 1163
++ S D ++K+W +
Sbjct: 365 ISASSDGTVKIWNM 378
Score = 39.5 bits (88), Expect = 0.087
Identities = 29/125 (23%), Positives = 56/125 (44%), Gaps = 11/125 (8%)
Query: 688 HTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIA---------P 738
H G + C + + QYL+TGS D + VW+ T ++ K L++ A
Sbjct: 208 HIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIR-KDLKYQAQDNFMMMDDA 266
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGNIFITGS 797
VLC+ + ++ +G D + + + G + + + H VT + +D + ++ S
Sbjct: 267 VLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSAS 326
Query: 798 QDGTV 802
D T+
Sbjct: 327 FDQTI 331
Score = 36.3 bits (80), Expect = 0.81
Identities = 30/130 (23%), Positives = 50/130 (38%), Gaps = 10/130 (7%)
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTD-------- 829
+ V + DG +TGS DG + WN + + + + D
Sbjct: 214 KSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFS 273
Query: 830 -DNVFLLTLQGDNELHLRTFITGTYLHPLKR-HKAKVKCFCVAHDSSRVAVGCADQRIYL 887
D L T D ++ + +G L +R H V C + DSS++ DQ I +
Sbjct: 274 RDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRI 333
Query: 888 YSLHSAQLLR 897
+ L S + L+
Sbjct: 334 HGLKSGKTLK 343
>BC021905-1|AAH21905.1| 896|Homo sapiens Unknown (protein for
IMAGE:4341693) protein.
Length = 896
Score = 73.7 bits (173), Expect = 4e-12
Identities = 74/339 (21%), Positives = 141/339 (41%), Gaps = 33/339 (9%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLS 1025
L + C+ R G+ +G LV++W RL ATL GH I+ + + N ++ +
Sbjct: 183 LSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAA 242
Query: 1026 GSEDRTVVVWQLADNSPSLTYKGHSSAIQTLL---MMSDGRRAMSSDRA-RNVHVWLVDS 1081
GS D+ + VW L +P +GHS++I +L + S +R +SS A + WL D+
Sbjct: 243 GSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDA 302
Query: 1082 GIV------LHSATGPSASIDVTLNMKYA---VLSDG--DNSVRIWSLAGGDNSEDNRRS 1130
G + P + + + A L+ G D+ +R++ G + +
Sbjct: 303 GTLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELE 362
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLV------------GHSDI 1178
H +++ + S V+GS D + ++W+ + +L+ G D
Sbjct: 363 F-HTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNLQGIEDK 421
Query: 1179 VTCVAVSIT----NKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV-TGDGTI 1233
+T + V++ + V++ + L VW+ T +V ++ D +
Sbjct: 422 ITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRV 481
Query: 1234 AVSCAEDKTLIIWETKRGLALTSFSLHVPLLGFQITSDC 1272
S D +I+W+ RG+ + S+ + G DC
Sbjct: 482 LFSAGHDGNVIVWDLARGVKIRSYFNMIEGQGHGAVFDC 520
Score = 64.9 bits (151), Expect = 2e-09
Identities = 52/221 (23%), Positives = 94/221 (42%), Gaps = 17/221 (7%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
++ + GH+ + CVTF + +GS+D V +W D T +GH++ I + +
Sbjct: 174 KMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAV 233
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-------VTLNMKYAVLSDGDN 1111
+ + + + VW + + L G SASI + + +Y + D
Sbjct: 234 NYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADG 293
Query: 1112 SVRIWSLAGGDNSEDNRRSVSHAER------ITCFALTADSQHVVTGSMDMSLKVWKLDG 1165
++ W G + N R ER + C + +A + TGS D ++V+
Sbjct: 294 TICFWLWDAG-TLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGS 352
Query: 1166 GKLSQV--LVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
G+ ++ L H+D V + S T+ + VSGS D +W
Sbjct: 353 GQPEKISELEFHTDKVDSIQFSNTS-NRFVSGSRDGTARIW 392
Score = 53.6 bits (123), Expect = 5e-06
Identities = 67/287 (23%), Positives = 107/287 (37%), Gaps = 33/287 (11%)
Query: 952 STTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHI 1011
+T + LL + IS + V+ + + A+G ++RVW L T A L GH I
Sbjct: 211 ATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASI 270
Query: 1012 TCVTFSP----NNLLVLSGSEDRTVVVW-------QLADNSPSLTYKGHSSAIQTLLMMS 1060
T + FSP + + S D T+ W ++ T + S
Sbjct: 271 TSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPAKFTERPRPGVQMICSSFS 330
Query: 1061 DGRRAMSSDRARN-VHVWLVDSG-----IVLHSATGPSASIDVTLNMKYAVLSDGDNSVR 1114
G +++ + + V+ SG L T SI + V D + R
Sbjct: 331 AGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTAR 390
Query: 1115 IWSL---------------AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLK 1159
IW G N + ++ ++T A V+T +M+LK
Sbjct: 391 IWQFKRREWKSILLDMATRPAGQNLQGIEDKITKM-KVTMVAWDRHDNTVITAVNNMTLK 449
Query: 1160 VWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
VW G+L VL+GH D V + + + S D N+IVWD+
Sbjct: 450 VWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDL 496
Score = 50.4 bits (115), Expect = 5e-05
Identities = 48/218 (22%), Positives = 90/218 (41%), Gaps = 16/218 (7%)
Query: 681 IMSNSKVHT-FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPV 739
+ + K+H GH S+ C+ R + + TGS+D V +W + + H A +
Sbjct: 169 VYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEI 228
Query: 740 LCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVK---VIQDGNIFITG 796
+A +++ +G D + + L A + L H S+TS++ + +++
Sbjct: 229 SDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSS 288
Query: 797 S-QDGTVCTWNVENFTL---------LSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLR 846
+ DGT+C W + TL GV + + +FL T D+ + +
Sbjct: 289 TGADGTICFWLWDAGTLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVY 348
Query: 847 TFITG--TYLHPLKRHKAKVKCFCVAHDSSRVAVGCAD 882
F +G + L+ H KV ++ S+R G D
Sbjct: 349 FFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRD 386
Score = 43.2 bits (97), Expect = 0.007
Identities = 33/143 (23%), Positives = 62/143 (43%), Gaps = 14/143 (9%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCM-----CVTRESQYLLTGSEDTSVI-VWDLHTLAVK- 729
++W + + + + +GHS SI + C + TG++ T +WD TL +
Sbjct: 250 RVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINP 309
Query: 730 --TKILEHIAP---VLCVAAIVNRSLVISGGDDSAVIITSLVDGA--LVTKLDHHRGSVT 782
K E P ++C + + +G D + + G +++L+ H V
Sbjct: 310 RPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVD 369
Query: 783 SVKVIQDGNIFITGSQDGTVCTW 805
S++ N F++GS+DGT W
Sbjct: 370 SIQFSNTSNRFVSGSRDGTARIW 392
Score = 34.3 bits (75), Expect = 3.3
Identities = 17/80 (21%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Query: 1167 KLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVK 1226
K+ + ++GH V CV T + ++ +GS DC + +W + +++ +
Sbjct: 174 KMHKRILGHLSSVYCVTFDRTGR-RIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMA 232
Query: 1227 VTGDGTIAVSCAEDKTLIIW 1246
V + T+ + + DK + +W
Sbjct: 233 VNYENTMIAAGSCDKMIRVW 252
Score = 34.3 bits (75), Expect = 3.3
Identities = 18/63 (28%), Positives = 28/63 (44%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + T +GH+ I M V E+ + GS D + VW L T A + H
Sbjct: 208 KIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHS 267
Query: 737 APV 739
A +
Sbjct: 268 ASI 270
>BC002876-1|AAH02876.1| 513|Homo sapiens smu-1 suppressor of mec-8
and unc-52 homolog (C. elegans) protein.
Length = 513
Score = 73.7 bits (173), Expect = 4e-12
Identities = 49/186 (26%), Positives = 86/186 (46%), Gaps = 9/186 (4%)
Query: 659 QLAPSGQHLVLAPSAGDPQLWH-----IMSNSKVHT---FKGHSGSILCMCVTRESQYLL 710
+ +P GQ+LV G ++W+ I + K F ++LCMC +R+++ L
Sbjct: 221 RFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLA 280
Query: 711 TGSEDTSVIVWDLHT-LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGA 769
TG++D + VW + + ++ H V C++ + S ++S D + I L G
Sbjct: 281 TGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGK 340
Query: 770 LVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTD 829
+ + H V QDG+ I+ S DGTV WN++ +T + D+T
Sbjct: 341 TLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITV 400
Query: 830 DNVFLL 835
++V LL
Sbjct: 401 NSVILL 406
Score = 68.5 bits (160), Expect = 2e-10
Identities = 56/230 (24%), Positives = 105/230 (45%), Gaps = 20/230 (8%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHR-LQATLNGHIGHITCVTFSPNNLLVLSGS 1027
+ C+ SRD ++ A+G G ++VW++ + + L+ H +TC++FS ++ +LS S
Sbjct: 267 VLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSAS 326
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHS 1087
D+T+ + L ++GHSS + DG +S+ V +W + + ++
Sbjct: 327 FDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNT 386
Query: 1088 --ATGPSASIDVTLNM--------KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAER- 1136
+ G +A D+T+N ++ V+ + N+V I ++ G RS S +R
Sbjct: 387 FKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQG-----QIVRSFSSGKRE 441
Query: 1137 ---ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVA 1183
C AL+ + + D L + GKL + L H V +A
Sbjct: 442 GGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIA 491
Score = 61.3 bits (142), Expect = 2e-08
Identities = 41/174 (23%), Positives = 73/174 (41%), Gaps = 7/174 (4%)
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHA-----ERITCFALTADSQHVVTGSMDM 1156
+Y V D + +W+ G +D + + + C + D++ + TG+ D
Sbjct: 227 QYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDG 286
Query: 1157 SLKVWKLDGGK-LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXX 1215
+KVWK+ G+ L + HS VTC++ S + +Q++S S+D + + + +
Sbjct: 287 KIKVWKIQSGQCLRRFERAHSKGVTCLSFS-KDSSQILSASFDQTIRIHGLKSGKTLKEF 345
Query: 1216 XXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLGFQIT 1269
V T DG +S + D T+ IW K +F G IT
Sbjct: 346 RGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDIT 399
Score = 56.4 bits (130), Expect = 7e-07
Identities = 34/162 (20%), Positives = 72/162 (44%), Gaps = 12/162 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHI--------GHITCVTFSPNN 1020
+ C S DGQ +G G + VW +T +++ L + C+ FS +
Sbjct: 217 VECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDT 276
Query: 1021 LLVLSGSEDRTVVVWQLADNSPSLTY-KGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLV 1079
++ +G++D + VW++ + + HS + L D + +S+ + + + +
Sbjct: 277 EMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGL 336
Query: 1080 DSGIVLHSATGPSASID---VTLNMKYAVLSDGDNSVRIWSL 1118
SG L G S+ ++ T + Y + + D +V+IW++
Sbjct: 337 KSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNM 378
Score = 50.4 bits (115), Expect = 5e-05
Identities = 36/133 (27%), Positives = 60/133 (45%), Gaps = 10/133 (7%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL--------VGHSDIVTCVAVSITN 1188
+ C + D Q++VTGS+D ++VW GK+ + L + D V C+ S +
Sbjct: 217 VECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFS-RD 275
Query: 1189 KTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-VTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+ +G+ D + VW I + K VTC+ + D + +S + D+T+ I
Sbjct: 276 TEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHG 335
Query: 1248 TKRGLALTSFSLH 1260
K G L F H
Sbjct: 336 LKSGKTLKEFRGH 348
Score = 46.8 bits (106), Expect = 6e-04
Identities = 38/194 (19%), Positives = 76/194 (39%), Gaps = 20/194 (10%)
Query: 987 RGLVRVWQLSTHRLQATLNGHI-----GHITCVTFSPNNLLVLSGSEDRTVVVWQLADNS 1041
RG V + + L+ HI H+ C FSP+ +++GS D + VW
Sbjct: 188 RGKAAVKDVEEEKFPTQLSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGK 247
Query: 1042 --PSLTYKGHSS------AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVL----HSAT 1089
L Y+ + A+ + D + + + VW + SG L + +
Sbjct: 248 IRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHS 307
Query: 1090 GPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHV 1149
+ + + + + D ++RI L G ++ R H+ + T D ++
Sbjct: 308 KGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFR---GHSSFVNEATFTQDGHYI 364
Query: 1150 VTGSMDMSLKVWKL 1163
++ S D ++K+W +
Sbjct: 365 ISASSDGTVKIWNM 378
Score = 39.5 bits (88), Expect = 0.087
Identities = 29/125 (23%), Positives = 56/125 (44%), Gaps = 11/125 (8%)
Query: 688 HTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIA---------P 738
H G + C + + QYL+TGS D + VW+ T ++ K L++ A
Sbjct: 208 HIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIR-KDLKYQAQDNFMMMDDA 266
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGNIFITGS 797
VLC+ + ++ +G D + + + G + + + H VT + +D + ++ S
Sbjct: 267 VLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSAS 326
Query: 798 QDGTV 802
D T+
Sbjct: 327 FDQTI 331
Score = 36.3 bits (80), Expect = 0.81
Identities = 30/130 (23%), Positives = 50/130 (38%), Gaps = 10/130 (7%)
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTD-------- 829
+ V + DG +TGS DG + WN + + + + D
Sbjct: 214 KSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFS 273
Query: 830 -DNVFLLTLQGDNELHLRTFITGTYLHPLKR-HKAKVKCFCVAHDSSRVAVGCADQRIYL 887
D L T D ++ + +G L +R H V C + DSS++ DQ I +
Sbjct: 274 RDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRI 333
Query: 888 YSLHSAQLLR 897
+ L S + L+
Sbjct: 334 HGLKSGKTLK 343
Score = 33.9 bits (74), Expect = 4.3
Identities = 34/152 (22%), Positives = 61/152 (40%), Gaps = 11/152 (7%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
G +++ A S G ++W++ + +TFK GS +T S LL + + V+
Sbjct: 361 GHYIISASSDGTVKIWNMKTTECSNTFKS-LGSTAGTDITVNSVILLPKNPEHFVVCNRS 419
Query: 724 HTLAVKT---KILEHIAP-------VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTK 773
+T+ + +I+ + +C A + G+D + S V G L
Sbjct: 420 NTVVIMNMQGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERT 479
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
L H V + N+ T S+DG + W
Sbjct: 480 LTVHEKDVIGIAHHPHQNLIATYSEDGLLKLW 511
>AL450327-2|CAH70884.1| 1821|Homo sapiens protein ( Human DNA sequence
from clone RP11-173D14 on chromosome 6. ).
Length = 1821
Score = 73.7 bits (173), Expect = 4e-12
Identities = 74/339 (21%), Positives = 141/339 (41%), Gaps = 33/339 (9%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLS 1025
L + C+ R G+ +G LV++W RL ATL GH I+ + + N ++ +
Sbjct: 183 LSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAA 242
Query: 1026 GSEDRTVVVWQLADNSPSLTYKGHSSAIQTLL---MMSDGRRAMSSDRA-RNVHVWLVDS 1081
GS D+ + VW L +P +GHS++I +L + S +R +SS A + WL D+
Sbjct: 243 GSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDA 302
Query: 1082 GIV------LHSATGPSASIDVTLNMKYA---VLSDG--DNSVRIWSLAGGDNSEDNRRS 1130
G + P + + + A L+ G D+ +R++ G + +
Sbjct: 303 GTLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELE 362
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLV------------GHSDI 1178
H +++ + S V+GS D + ++W+ + +L+ G D
Sbjct: 363 F-HTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNLQGIEDK 421
Query: 1179 VTCVAVSIT----NKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV-TGDGTI 1233
+T + V++ + V++ + L VW+ T +V ++ D +
Sbjct: 422 ITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRV 481
Query: 1234 AVSCAEDKTLIIWETKRGLALTSFSLHVPLLGFQITSDC 1272
S D +I+W+ RG+ + S+ + G DC
Sbjct: 482 LFSAGHDGNVIVWDLARGVKIRSYFNMIEGQGHGAVFDC 520
Score = 64.9 bits (151), Expect = 2e-09
Identities = 52/221 (23%), Positives = 94/221 (42%), Gaps = 17/221 (7%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
++ + GH+ + CVTF + +GS+D V +W D T +GH++ I + +
Sbjct: 174 KMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAV 233
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-------VTLNMKYAVLSDGDN 1111
+ + + + VW + + L G SASI + + +Y + D
Sbjct: 234 NYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADG 293
Query: 1112 SVRIWSLAGGDNSEDNRRSVSHAER------ITCFALTADSQHVVTGSMDMSLKVWKLDG 1165
++ W G + N R ER + C + +A + TGS D ++V+
Sbjct: 294 TICFWLWDAG-TLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGS 352
Query: 1166 GKLSQV--LVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
G+ ++ L H+D V + S T+ + VSGS D +W
Sbjct: 353 GQPEKISELEFHTDKVDSIQFSNTS-NRFVSGSRDGTARIW 392
Score = 53.6 bits (123), Expect = 5e-06
Identities = 67/287 (23%), Positives = 107/287 (37%), Gaps = 33/287 (11%)
Query: 952 STTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHI 1011
+T + LL + IS + V+ + + A+G ++RVW L T A L GH I
Sbjct: 211 ATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASI 270
Query: 1012 TCVTFSP----NNLLVLSGSEDRTVVVW-------QLADNSPSLTYKGHSSAIQTLLMMS 1060
T + FSP + + S D T+ W ++ T + S
Sbjct: 271 TSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPAKFTERPRPGVQMICSSFS 330
Query: 1061 DGRRAMSSDRARN-VHVWLVDSG-----IVLHSATGPSASIDVTLNMKYAVLSDGDNSVR 1114
G +++ + + V+ SG L T SI + V D + R
Sbjct: 331 AGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTAR 390
Query: 1115 IWSL---------------AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLK 1159
IW G N + ++ ++T A V+T +M+LK
Sbjct: 391 IWQFKRREWKSILLDMATRPAGQNLQGIEDKITKM-KVTMVAWDRHDNTVITAVNNMTLK 449
Query: 1160 VWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
VW G+L VL+GH D V + + + S D N+IVWD+
Sbjct: 450 VWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDL 496
Score = 50.4 bits (115), Expect = 5e-05
Identities = 48/218 (22%), Positives = 90/218 (41%), Gaps = 16/218 (7%)
Query: 681 IMSNSKVHT-FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPV 739
+ + K+H GH S+ C+ R + + TGS+D V +W + + H A +
Sbjct: 169 VYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEI 228
Query: 740 LCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVK---VIQDGNIFITG 796
+A +++ +G D + + L A + L H S+TS++ + +++
Sbjct: 229 SDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSS 288
Query: 797 S-QDGTVCTWNVENFTL---------LSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLR 846
+ DGT+C W + TL GV + + +FL T D+ + +
Sbjct: 289 TGADGTICFWLWDAGTLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVY 348
Query: 847 TFITG--TYLHPLKRHKAKVKCFCVAHDSSRVAVGCAD 882
F +G + L+ H KV ++ S+R G D
Sbjct: 349 FFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRD 386
Score = 43.2 bits (97), Expect = 0.007
Identities = 33/143 (23%), Positives = 62/143 (43%), Gaps = 14/143 (9%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCM-----CVTRESQYLLTGSEDTSVI-VWDLHTLAVK- 729
++W + + + + +GHS SI + C + TG++ T +WD TL +
Sbjct: 250 RVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINP 309
Query: 730 --TKILEHIAP---VLCVAAIVNRSLVISGGDDSAVIITSLVDGA--LVTKLDHHRGSVT 782
K E P ++C + + +G D + + G +++L+ H V
Sbjct: 310 RPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVD 369
Query: 783 SVKVIQDGNIFITGSQDGTVCTW 805
S++ N F++GS+DGT W
Sbjct: 370 SIQFSNTSNRFVSGSRDGTARIW 392
Score = 34.3 bits (75), Expect = 3.3
Identities = 17/80 (21%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Query: 1167 KLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVK 1226
K+ + ++GH V CV T + ++ +GS DC + +W + +++ +
Sbjct: 174 KMHKRILGHLSSVYCVTFDRTGR-RIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMA 232
Query: 1227 VTGDGTIAVSCAEDKTLIIW 1246
V + T+ + + DK + +W
Sbjct: 233 VNYENTMIAAGSCDKMIRVW 252
Score = 34.3 bits (75), Expect = 3.3
Identities = 18/63 (28%), Positives = 28/63 (44%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + T +GH+ I M V E+ + GS D + VW L T A + H
Sbjct: 208 KIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHS 267
Query: 737 APV 739
A +
Sbjct: 268 ASI 270
>AL356776-2|CAI14406.1| 1821|Homo sapiens protein ( Human DNA sequence
from clone RP11-477E3 on chromosome 6. ).
Length = 1821
Score = 73.7 bits (173), Expect = 4e-12
Identities = 74/339 (21%), Positives = 141/339 (41%), Gaps = 33/339 (9%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLS 1025
L + C+ R G+ +G LV++W RL ATL GH I+ + + N ++ +
Sbjct: 183 LSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAA 242
Query: 1026 GSEDRTVVVWQLADNSPSLTYKGHSSAIQTLL---MMSDGRRAMSSDRA-RNVHVWLVDS 1081
GS D+ + VW L +P +GHS++I +L + S +R +SS A + WL D+
Sbjct: 243 GSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDA 302
Query: 1082 GIV------LHSATGPSASIDVTLNMKYA---VLSDG--DNSVRIWSLAGGDNSEDNRRS 1130
G + P + + + A L+ G D+ +R++ G + +
Sbjct: 303 GTLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELE 362
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLV------------GHSDI 1178
H +++ + S V+GS D + ++W+ + +L+ G D
Sbjct: 363 F-HTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNLQGIEDK 421
Query: 1179 VTCVAVSIT----NKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV-TGDGTI 1233
+T + V++ + V++ + L VW+ T +V ++ D +
Sbjct: 422 ITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRV 481
Query: 1234 AVSCAEDKTLIIWETKRGLALTSFSLHVPLLGFQITSDC 1272
S D +I+W+ RG+ + S+ + G DC
Sbjct: 482 LFSAGHDGNVIVWDLARGVKIRSYFNMIEGQGHGAVFDC 520
Score = 64.9 bits (151), Expect = 2e-09
Identities = 52/221 (23%), Positives = 94/221 (42%), Gaps = 17/221 (7%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
++ + GH+ + CVTF + +GS+D V +W D T +GH++ I + +
Sbjct: 174 KMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAV 233
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-------VTLNMKYAVLSDGDN 1111
+ + + + VW + + L G SASI + + +Y + D
Sbjct: 234 NYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADG 293
Query: 1112 SVRIWSLAGGDNSEDNRRSVSHAER------ITCFALTADSQHVVTGSMDMSLKVWKLDG 1165
++ W G + N R ER + C + +A + TGS D ++V+
Sbjct: 294 TICFWLWDAG-TLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGS 352
Query: 1166 GKLSQV--LVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
G+ ++ L H+D V + S T+ + VSGS D +W
Sbjct: 353 GQPEKISELEFHTDKVDSIQFSNTS-NRFVSGSRDGTARIW 392
Score = 53.6 bits (123), Expect = 5e-06
Identities = 67/287 (23%), Positives = 107/287 (37%), Gaps = 33/287 (11%)
Query: 952 STTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHI 1011
+T + LL + IS + V+ + + A+G ++RVW L T A L GH I
Sbjct: 211 ATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASI 270
Query: 1012 TCVTFSP----NNLLVLSGSEDRTVVVW-------QLADNSPSLTYKGHSSAIQTLLMMS 1060
T + FSP + + S D T+ W ++ T + S
Sbjct: 271 TSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPAKFTERPRPGVQMICSSFS 330
Query: 1061 DGRRAMSSDRARN-VHVWLVDSG-----IVLHSATGPSASIDVTLNMKYAVLSDGDNSVR 1114
G +++ + + V+ SG L T SI + V D + R
Sbjct: 331 AGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTAR 390
Query: 1115 IWSL---------------AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLK 1159
IW G N + ++ ++T A V+T +M+LK
Sbjct: 391 IWQFKRREWKSILLDMATRPAGQNLQGIEDKITKM-KVTMVAWDRHDNTVITAVNNMTLK 449
Query: 1160 VWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
VW G+L VL+GH D V + + + S D N+IVWD+
Sbjct: 450 VWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDL 496
Score = 50.4 bits (115), Expect = 5e-05
Identities = 48/218 (22%), Positives = 90/218 (41%), Gaps = 16/218 (7%)
Query: 681 IMSNSKVHT-FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPV 739
+ + K+H GH S+ C+ R + + TGS+D V +W + + H A +
Sbjct: 169 VYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEI 228
Query: 740 LCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVK---VIQDGNIFITG 796
+A +++ +G D + + L A + L H S+TS++ + +++
Sbjct: 229 SDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSS 288
Query: 797 S-QDGTVCTWNVENFTL---------LSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLR 846
+ DGT+C W + TL GV + + +FL T D+ + +
Sbjct: 289 TGADGTICFWLWDAGTLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVY 348
Query: 847 TFITG--TYLHPLKRHKAKVKCFCVAHDSSRVAVGCAD 882
F +G + L+ H KV ++ S+R G D
Sbjct: 349 FFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRD 386
Score = 43.2 bits (97), Expect = 0.007
Identities = 33/143 (23%), Positives = 62/143 (43%), Gaps = 14/143 (9%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCM-----CVTRESQYLLTGSEDTSVI-VWDLHTLAVK- 729
++W + + + + +GHS SI + C + TG++ T +WD TL +
Sbjct: 250 RVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINP 309
Query: 730 --TKILEHIAP---VLCVAAIVNRSLVISGGDDSAVIITSLVDGA--LVTKLDHHRGSVT 782
K E P ++C + + +G D + + G +++L+ H V
Sbjct: 310 RPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVD 369
Query: 783 SVKVIQDGNIFITGSQDGTVCTW 805
S++ N F++GS+DGT W
Sbjct: 370 SIQFSNTSNRFVSGSRDGTARIW 392
Score = 34.3 bits (75), Expect = 3.3
Identities = 17/80 (21%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Query: 1167 KLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVK 1226
K+ + ++GH V CV T + ++ +GS DC + +W + +++ +
Sbjct: 174 KMHKRILGHLSSVYCVTFDRTGR-RIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMA 232
Query: 1227 VTGDGTIAVSCAEDKTLIIW 1246
V + T+ + + DK + +W
Sbjct: 233 VNYENTMIAAGSCDKMIRVW 252
Score = 34.3 bits (75), Expect = 3.3
Identities = 18/63 (28%), Positives = 28/63 (44%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + T +GH+ I M V E+ + GS D + VW L T A + H
Sbjct: 208 KIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHS 267
Query: 737 APV 739
A +
Sbjct: 268 ASI 270
>AL162590-6|CAI15554.1| 513|Homo sapiens smu-1 suppressor of mec-8
and unc-52 homolog (C. elegans) protein.
Length = 513
Score = 73.7 bits (173), Expect = 4e-12
Identities = 49/186 (26%), Positives = 86/186 (46%), Gaps = 9/186 (4%)
Query: 659 QLAPSGQHLVLAPSAGDPQLWH-----IMSNSKVHT---FKGHSGSILCMCVTRESQYLL 710
+ +P GQ+LV G ++W+ I + K F ++LCMC +R+++ L
Sbjct: 221 RFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLA 280
Query: 711 TGSEDTSVIVWDLHT-LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGA 769
TG++D + VW + + ++ H V C++ + S ++S D + I L G
Sbjct: 281 TGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGK 340
Query: 770 LVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTD 829
+ + H V QDG+ I+ S DGTV WN++ +T + D+T
Sbjct: 341 TLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITV 400
Query: 830 DNVFLL 835
++V LL
Sbjct: 401 NSVILL 406
Score = 68.5 bits (160), Expect = 2e-10
Identities = 56/230 (24%), Positives = 105/230 (45%), Gaps = 20/230 (8%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHR-LQATLNGHIGHITCVTFSPNNLLVLSGS 1027
+ C+ SRD ++ A+G G ++VW++ + + L+ H +TC++FS ++ +LS S
Sbjct: 267 VLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSAS 326
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHS 1087
D+T+ + L ++GHSS + DG +S+ V +W + + ++
Sbjct: 327 FDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNT 386
Query: 1088 --ATGPSASIDVTLNM--------KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAER- 1136
+ G +A D+T+N ++ V+ + N+V I ++ G RS S +R
Sbjct: 387 FKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQG-----QIVRSFSSGKRE 441
Query: 1137 ---ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVA 1183
C AL+ + + D L + GKL + L H V +A
Sbjct: 442 GGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIA 491
Score = 61.3 bits (142), Expect = 2e-08
Identities = 41/174 (23%), Positives = 73/174 (41%), Gaps = 7/174 (4%)
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHA-----ERITCFALTADSQHVVTGSMDM 1156
+Y V D + +W+ G +D + + + C + D++ + TG+ D
Sbjct: 227 QYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDG 286
Query: 1157 SLKVWKLDGGK-LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXX 1215
+KVWK+ G+ L + HS VTC++ S + +Q++S S+D + + + +
Sbjct: 287 KIKVWKIQSGQCLRRFERAHSKGVTCLSFS-KDSSQILSASFDQTIRIHGLKSGKTLKEF 345
Query: 1216 XXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLGFQIT 1269
V T DG +S + D T+ IW K +F G IT
Sbjct: 346 RGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDIT 399
Score = 56.4 bits (130), Expect = 7e-07
Identities = 34/162 (20%), Positives = 72/162 (44%), Gaps = 12/162 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHI--------GHITCVTFSPNN 1020
+ C S DGQ +G G + VW +T +++ L + C+ FS +
Sbjct: 217 VECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDT 276
Query: 1021 LLVLSGSEDRTVVVWQLADNSPSLTY-KGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLV 1079
++ +G++D + VW++ + + HS + L D + +S+ + + + +
Sbjct: 277 EMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGL 336
Query: 1080 DSGIVLHSATGPSASID---VTLNMKYAVLSDGDNSVRIWSL 1118
SG L G S+ ++ T + Y + + D +V+IW++
Sbjct: 337 KSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNM 378
Score = 50.4 bits (115), Expect = 5e-05
Identities = 36/133 (27%), Positives = 60/133 (45%), Gaps = 10/133 (7%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL--------VGHSDIVTCVAVSITN 1188
+ C + D Q++VTGS+D ++VW GK+ + L + D V C+ S +
Sbjct: 217 VECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFS-RD 275
Query: 1189 KTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-VTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+ +G+ D + VW I + K VTC+ + D + +S + D+T+ I
Sbjct: 276 TEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHG 335
Query: 1248 TKRGLALTSFSLH 1260
K G L F H
Sbjct: 336 LKSGKTLKEFRGH 348
Score = 46.8 bits (106), Expect = 6e-04
Identities = 38/194 (19%), Positives = 76/194 (39%), Gaps = 20/194 (10%)
Query: 987 RGLVRVWQLSTHRLQATLNGHI-----GHITCVTFSPNNLLVLSGSEDRTVVVWQLADNS 1041
RG V + + L+ HI H+ C FSP+ +++GS D + VW
Sbjct: 188 RGKAAVKDVEEEKFPTQLSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGK 247
Query: 1042 --PSLTYKGHSS------AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVL----HSAT 1089
L Y+ + A+ + D + + + VW + SG L + +
Sbjct: 248 IRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHS 307
Query: 1090 GPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHV 1149
+ + + + + D ++RI L G ++ R H+ + T D ++
Sbjct: 308 KGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFR---GHSSFVNEATFTQDGHYI 364
Query: 1150 VTGSMDMSLKVWKL 1163
++ S D ++K+W +
Sbjct: 365 ISASSDGTVKIWNM 378
Score = 39.5 bits (88), Expect = 0.087
Identities = 29/125 (23%), Positives = 56/125 (44%), Gaps = 11/125 (8%)
Query: 688 HTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIA---------P 738
H G + C + + QYL+TGS D + VW+ T ++ K L++ A
Sbjct: 208 HIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIR-KDLKYQAQDNFMMMDDA 266
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGNIFITGS 797
VLC+ + ++ +G D + + + G + + + H VT + +D + ++ S
Sbjct: 267 VLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSAS 326
Query: 798 QDGTV 802
D T+
Sbjct: 327 FDQTI 331
Score = 36.3 bits (80), Expect = 0.81
Identities = 30/130 (23%), Positives = 50/130 (38%), Gaps = 10/130 (7%)
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTD-------- 829
+ V + DG +TGS DG + WN + + + + D
Sbjct: 214 KSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFS 273
Query: 830 -DNVFLLTLQGDNELHLRTFITGTYLHPLKR-HKAKVKCFCVAHDSSRVAVGCADQRIYL 887
D L T D ++ + +G L +R H V C + DSS++ DQ I +
Sbjct: 274 RDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRI 333
Query: 888 YSLHSAQLLR 897
+ L S + L+
Sbjct: 334 HGLKSGKTLK 343
Score = 33.9 bits (74), Expect = 4.3
Identities = 34/152 (22%), Positives = 61/152 (40%), Gaps = 11/152 (7%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
G +++ A S G ++W++ + +TFK GS +T S LL + + V+
Sbjct: 361 GHYIISASSDGTVKIWNMKTTECSNTFKS-LGSTAGTDITVNSVILLPKNPEHFVVCNRS 419
Query: 724 HTLAVKT---KILEHIAP-------VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTK 773
+T+ + +I+ + +C A + G+D + S V G L
Sbjct: 420 NTVVIMNMQGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERT 479
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
L H V + N+ T S+DG + W
Sbjct: 480 LTVHEKDVIGIAHHPHQNLIATYSEDGLLKLW 511
>AK057039-1|BAB71353.1| 912|Homo sapiens protein ( Homo sapiens cDNA
FLJ32477 fis, clone SKNMC2000698, highly similar to Mus
musculus ndrp mRNA for neuronal differentiaion related ).
Length = 912
Score = 73.7 bits (173), Expect = 4e-12
Identities = 74/339 (21%), Positives = 141/339 (41%), Gaps = 33/339 (9%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLS 1025
L + C+ R G+ +G LV++W RL ATL GH I+ + + N ++ +
Sbjct: 183 LSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAA 242
Query: 1026 GSEDRTVVVWQLADNSPSLTYKGHSSAIQTLL---MMSDGRRAMSSDRA-RNVHVWLVDS 1081
GS D+ + VW L +P +GHS++I +L + S +R +SS A + WL D+
Sbjct: 243 GSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDA 302
Query: 1082 GIV------LHSATGPSASIDVTLNMKYA---VLSDG--DNSVRIWSLAGGDNSEDNRRS 1130
G + P + + + A L+ G D+ +R++ G + +
Sbjct: 303 GTLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELE 362
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLV------------GHSDI 1178
H +++ + S V+GS D + ++W+ + +L+ G D
Sbjct: 363 F-HTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNLQGIEDK 421
Query: 1179 VTCVAVSIT----NKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV-TGDGTI 1233
+T + V++ + V++ + L VW+ T +V ++ D +
Sbjct: 422 ITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRV 481
Query: 1234 AVSCAEDKTLIIWETKRGLALTSFSLHVPLLGFQITSDC 1272
S D +I+W+ RG+ + S+ + G DC
Sbjct: 482 LFSAGHDGNVIVWDLARGVKIRSYFNMIEGQGHGAVFDC 520
Score = 64.9 bits (151), Expect = 2e-09
Identities = 52/221 (23%), Positives = 94/221 (42%), Gaps = 17/221 (7%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
++ + GH+ + CVTF + +GS+D V +W D T +GH++ I + +
Sbjct: 174 KMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAV 233
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-------VTLNMKYAVLSDGDN 1111
+ + + + VW + + L G SASI + + +Y + D
Sbjct: 234 NYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADG 293
Query: 1112 SVRIWSLAGGDNSEDNRRSVSHAER------ITCFALTADSQHVVTGSMDMSLKVWKLDG 1165
++ W G + N R ER + C + +A + TGS D ++V+
Sbjct: 294 TICFWLWDAG-TLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGS 352
Query: 1166 GKLSQV--LVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
G+ ++ L H+D V + S T+ + VSGS D +W
Sbjct: 353 GQPEKISELEFHTDKVDSIQFSNTS-NRFVSGSRDGTARIW 392
Score = 53.6 bits (123), Expect = 5e-06
Identities = 67/287 (23%), Positives = 107/287 (37%), Gaps = 33/287 (11%)
Query: 952 STTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHI 1011
+T + LL + IS + V+ + + A+G ++RVW L T A L GH I
Sbjct: 211 ATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASI 270
Query: 1012 TCVTFSP----NNLLVLSGSEDRTVVVW-------QLADNSPSLTYKGHSSAIQTLLMMS 1060
T + FSP + + S D T+ W ++ T + S
Sbjct: 271 TSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPAKFTERPRPGVQMICSSFS 330
Query: 1061 DGRRAMSSDRARN-VHVWLVDSG-----IVLHSATGPSASIDVTLNMKYAVLSDGDNSVR 1114
G +++ + + V+ SG L T SI + V D + R
Sbjct: 331 AGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTAR 390
Query: 1115 IWSL---------------AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLK 1159
IW G N + ++ ++T A V+T +M+LK
Sbjct: 391 IWQFKRREWKSILLDMATRPAGQNLQGIEDKITKM-KVTMVAWDRHDNTVITAVNNMTLK 449
Query: 1160 VWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
VW G+L VL+GH D V + + + S D N+IVWD+
Sbjct: 450 VWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDL 496
Score = 50.4 bits (115), Expect = 5e-05
Identities = 48/218 (22%), Positives = 90/218 (41%), Gaps = 16/218 (7%)
Query: 681 IMSNSKVHT-FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPV 739
+ + K+H GH S+ C+ R + + TGS+D V +W + + H A +
Sbjct: 169 VYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEI 228
Query: 740 LCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVK---VIQDGNIFITG 796
+A +++ +G D + + L A + L H S+TS++ + +++
Sbjct: 229 SDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSS 288
Query: 797 S-QDGTVCTWNVENFTL---------LSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLR 846
+ DGT+C W + TL GV + + +FL T D+ + +
Sbjct: 289 TGADGTICFWLWDAGTLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVY 348
Query: 847 TFITG--TYLHPLKRHKAKVKCFCVAHDSSRVAVGCAD 882
F +G + L+ H KV ++ S+R G D
Sbjct: 349 FFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRD 386
Score = 43.2 bits (97), Expect = 0.007
Identities = 33/143 (23%), Positives = 62/143 (43%), Gaps = 14/143 (9%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCM-----CVTRESQYLLTGSEDTSVI-VWDLHTLAVK- 729
++W + + + + +GHS SI + C + TG++ T +WD TL +
Sbjct: 250 RVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINP 309
Query: 730 --TKILEHIAP---VLCVAAIVNRSLVISGGDDSAVIITSLVDGA--LVTKLDHHRGSVT 782
K E P ++C + + +G D + + G +++L+ H V
Sbjct: 310 RPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVD 369
Query: 783 SVKVIQDGNIFITGSQDGTVCTW 805
S++ N F++GS+DGT W
Sbjct: 370 SIQFSNTSNRFVSGSRDGTARIW 392
Score = 34.3 bits (75), Expect = 3.3
Identities = 17/80 (21%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Query: 1167 KLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVK 1226
K+ + ++GH V CV T + ++ +GS DC + +W + +++ +
Sbjct: 174 KMHKRILGHLSSVYCVTFDRTGR-RIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMA 232
Query: 1227 VTGDGTIAVSCAEDKTLIIW 1246
V + T+ + + DK + +W
Sbjct: 233 VNYENTMIAAGSCDKMIRVW 252
Score = 34.3 bits (75), Expect = 3.3
Identities = 18/63 (28%), Positives = 28/63 (44%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + T +GH+ I M V E+ + GS D + VW L T A + H
Sbjct: 208 KIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHS 267
Query: 737 APV 739
A +
Sbjct: 268 ASI 270
>AK001667-1|BAA91822.1| 513|Homo sapiens protein ( Homo sapiens
cDNA FLJ10805 fis, clone NT2RP4000839, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 513
Score = 73.7 bits (173), Expect = 4e-12
Identities = 49/186 (26%), Positives = 86/186 (46%), Gaps = 9/186 (4%)
Query: 659 QLAPSGQHLVLAPSAGDPQLWH-----IMSNSKVHT---FKGHSGSILCMCVTRESQYLL 710
+ +P GQ+LV G ++W+ I + K F ++LCMC +R+++ L
Sbjct: 221 RFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLA 280
Query: 711 TGSEDTSVIVWDLHT-LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGA 769
TG++D + VW + + ++ H V C++ + S ++S D + I L G
Sbjct: 281 TGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGK 340
Query: 770 LVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTD 829
+ + H V QDG+ I+ S DGTV WN++ +T + D+T
Sbjct: 341 TLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITV 400
Query: 830 DNVFLL 835
++V LL
Sbjct: 401 NSVILL 406
Score = 68.5 bits (160), Expect = 2e-10
Identities = 56/230 (24%), Positives = 105/230 (45%), Gaps = 20/230 (8%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHR-LQATLNGHIGHITCVTFSPNNLLVLSGS 1027
+ C+ SRD ++ A+G G ++VW++ + + L+ H +TC++FS ++ +LS S
Sbjct: 267 VLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSAS 326
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHS 1087
D+T+ + L ++GHSS + DG +S+ V +W + + ++
Sbjct: 327 FDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNT 386
Query: 1088 --ATGPSASIDVTLNM--------KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAER- 1136
+ G +A D+T+N ++ V+ + N+V I ++ G RS S +R
Sbjct: 387 FKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQG-----QIVRSFSSGKRE 441
Query: 1137 ---ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVA 1183
C AL+ + + D L + GKL + L H V +A
Sbjct: 442 GGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIA 491
Score = 61.3 bits (142), Expect = 2e-08
Identities = 41/174 (23%), Positives = 73/174 (41%), Gaps = 7/174 (4%)
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHA-----ERITCFALTADSQHVVTGSMDM 1156
+Y V D + +W+ G +D + + + C + D++ + TG+ D
Sbjct: 227 QYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDG 286
Query: 1157 SLKVWKLDGGK-LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXX 1215
+KVWK+ G+ L + HS VTC++ S + +Q++S S+D + + + +
Sbjct: 287 KIKVWKIQSGQCLRRFERAHSKGVTCLSFS-KDSSQILSASFDQTIRIHGLKSGKTLKEF 345
Query: 1216 XXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLGFQIT 1269
V T DG +S + D T+ IW K +F G IT
Sbjct: 346 RGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDIT 399
Score = 56.4 bits (130), Expect = 7e-07
Identities = 34/162 (20%), Positives = 72/162 (44%), Gaps = 12/162 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHI--------GHITCVTFSPNN 1020
+ C S DGQ +G G + VW +T +++ L + C+ FS +
Sbjct: 217 VECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDT 276
Query: 1021 LLVLSGSEDRTVVVWQLADNSPSLTY-KGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLV 1079
++ +G++D + VW++ + + HS + L D + +S+ + + + +
Sbjct: 277 EMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGL 336
Query: 1080 DSGIVLHSATGPSASID---VTLNMKYAVLSDGDNSVRIWSL 1118
SG L G S+ ++ T + Y + + D +V+IW++
Sbjct: 337 KSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNM 378
Score = 50.4 bits (115), Expect = 5e-05
Identities = 36/133 (27%), Positives = 60/133 (45%), Gaps = 10/133 (7%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL--------VGHSDIVTCVAVSITN 1188
+ C + D Q++VTGS+D ++VW GK+ + L + D V C+ S +
Sbjct: 217 VECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFS-RD 275
Query: 1189 KTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-VTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+ +G+ D + VW I + K VTC+ + D + +S + D+T+ I
Sbjct: 276 TEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHG 335
Query: 1248 TKRGLALTSFSLH 1260
K G L F H
Sbjct: 336 LKSGKTLKEFRGH 348
Score = 46.8 bits (106), Expect = 6e-04
Identities = 38/194 (19%), Positives = 76/194 (39%), Gaps = 20/194 (10%)
Query: 987 RGLVRVWQLSTHRLQATLNGHI-----GHITCVTFSPNNLLVLSGSEDRTVVVWQLADNS 1041
RG V + + L+ HI H+ C FSP+ +++GS D + VW
Sbjct: 188 RGKAAVKDVEEEKFPTQLSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGK 247
Query: 1042 --PSLTYKGHSS------AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVL----HSAT 1089
L Y+ + A+ + D + + + VW + SG L + +
Sbjct: 248 IRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHS 307
Query: 1090 GPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHV 1149
+ + + + + D ++RI L G ++ R H+ + T D ++
Sbjct: 308 KGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFR---GHSSFVNEATFTQDGHYI 364
Query: 1150 VTGSMDMSLKVWKL 1163
++ S D ++K+W +
Sbjct: 365 ISASSDGTVKIWNM 378
Score = 39.5 bits (88), Expect = 0.087
Identities = 29/125 (23%), Positives = 56/125 (44%), Gaps = 11/125 (8%)
Query: 688 HTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIA---------P 738
H G + C + + QYL+TGS D + VW+ T ++ K L++ A
Sbjct: 208 HIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIR-KDLKYQAQDNFMMMDDA 266
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGNIFITGS 797
VLC+ + ++ +G D + + + G + + + H VT + +D + ++ S
Sbjct: 267 VLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSAS 326
Query: 798 QDGTV 802
D T+
Sbjct: 327 FDQTI 331
Score = 36.3 bits (80), Expect = 0.81
Identities = 30/130 (23%), Positives = 50/130 (38%), Gaps = 10/130 (7%)
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTD-------- 829
+ V + DG +TGS DG + WN + + + + D
Sbjct: 214 KSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFS 273
Query: 830 -DNVFLLTLQGDNELHLRTFITGTYLHPLKR-HKAKVKCFCVAHDSSRVAVGCADQRIYL 887
D L T D ++ + +G L +R H V C + DSS++ DQ I +
Sbjct: 274 RDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRI 333
Query: 888 YSLHSAQLLR 897
+ L S + L+
Sbjct: 334 HGLKSGKTLK 343
>AJ303102-1|CAC83118.1| 1821|Homo sapiens WD repeat domain 11 protein
protein.
Length = 1821
Score = 73.7 bits (173), Expect = 4e-12
Identities = 74/339 (21%), Positives = 141/339 (41%), Gaps = 33/339 (9%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLS 1025
L + C+ R G+ +G LV++W RL ATL GH I+ + + N ++ +
Sbjct: 183 LSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAA 242
Query: 1026 GSEDRTVVVWQLADNSPSLTYKGHSSAIQTLL---MMSDGRRAMSSDRA-RNVHVWLVDS 1081
GS D+ + VW L +P +GHS++I +L + S +R +SS A + WL D+
Sbjct: 243 GSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDA 302
Query: 1082 GIV------LHSATGPSASIDVTLNMKYA---VLSDG--DNSVRIWSLAGGDNSEDNRRS 1130
G + P + + + A L+ G D+ +R++ G + +
Sbjct: 303 GTLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELE 362
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLV------------GHSDI 1178
H +++ + S V+GS D + ++W+ + +L+ G D
Sbjct: 363 F-HTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNLQGIEDK 421
Query: 1179 VTCVAVSIT----NKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV-TGDGTI 1233
+T + V++ + V++ + L VW+ T +V ++ D +
Sbjct: 422 ITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRV 481
Query: 1234 AVSCAEDKTLIIWETKRGLALTSFSLHVPLLGFQITSDC 1272
S D +I+W+ RG+ + S+ + G DC
Sbjct: 482 LFSAGHDGNVIVWDLARGVKIRSYFNMIEGQGHGAVFDC 520
Score = 64.9 bits (151), Expect = 2e-09
Identities = 52/221 (23%), Positives = 94/221 (42%), Gaps = 17/221 (7%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
++ + GH+ + CVTF + +GS+D V +W D T +GH++ I + +
Sbjct: 174 KMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAV 233
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-------VTLNMKYAVLSDGDN 1111
+ + + + VW + + L G SASI + + +Y + D
Sbjct: 234 NYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADG 293
Query: 1112 SVRIWSLAGGDNSEDNRRSVSHAER------ITCFALTADSQHVVTGSMDMSLKVWKLDG 1165
++ W G + N R ER + C + +A + TGS D ++V+
Sbjct: 294 TICFWLWDAG-TLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGS 352
Query: 1166 GKLSQV--LVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
G+ ++ L H+D V + S T+ + VSGS D +W
Sbjct: 353 GQPEKISELEFHTDKVDSIQFSNTS-NRFVSGSRDGTARIW 392
Score = 53.6 bits (123), Expect = 5e-06
Identities = 67/287 (23%), Positives = 107/287 (37%), Gaps = 33/287 (11%)
Query: 952 STTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHI 1011
+T + LL + IS + V+ + + A+G ++RVW L T A L GH I
Sbjct: 211 ATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASI 270
Query: 1012 TCVTFSP----NNLLVLSGSEDRTVVVW-------QLADNSPSLTYKGHSSAIQTLLMMS 1060
T + FSP + + S D T+ W ++ T + S
Sbjct: 271 TSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPAKFTERPRPGVQMICSSFS 330
Query: 1061 DGRRAMSSDRARN-VHVWLVDSG-----IVLHSATGPSASIDVTLNMKYAVLSDGDNSVR 1114
G +++ + + V+ SG L T SI + V D + R
Sbjct: 331 AGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTAR 390
Query: 1115 IWSL---------------AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLK 1159
IW G N + ++ ++T A V+T +M+LK
Sbjct: 391 IWQFKRREWKSILLDMATRPAGQNLQGIEDKITKM-KVTMVAWDRHDNTVITAVNNMTLK 449
Query: 1160 VWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
VW G+L VL+GH D V + + + S D N+IVWD+
Sbjct: 450 VWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDL 496
Score = 50.4 bits (115), Expect = 5e-05
Identities = 48/218 (22%), Positives = 90/218 (41%), Gaps = 16/218 (7%)
Query: 681 IMSNSKVHT-FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPV 739
+ + K+H GH S+ C+ R + + TGS+D V +W + + H A +
Sbjct: 169 VYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEI 228
Query: 740 LCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVK---VIQDGNIFITG 796
+A +++ +G D + + L A + L H S+TS++ + +++
Sbjct: 229 SDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSS 288
Query: 797 S-QDGTVCTWNVENFTL---------LSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLR 846
+ DGT+C W + TL GV + + +FL T D+ + +
Sbjct: 289 TGADGTICFWLWDAGTLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVY 348
Query: 847 TFITG--TYLHPLKRHKAKVKCFCVAHDSSRVAVGCAD 882
F +G + L+ H KV ++ S+R G D
Sbjct: 349 FFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRD 386
Score = 43.2 bits (97), Expect = 0.007
Identities = 33/143 (23%), Positives = 62/143 (43%), Gaps = 14/143 (9%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCM-----CVTRESQYLLTGSEDTSVI-VWDLHTLAVK- 729
++W + + + + +GHS SI + C + TG++ T +WD TL +
Sbjct: 250 RVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINP 309
Query: 730 --TKILEHIAP---VLCVAAIVNRSLVISGGDDSAVIITSLVDGA--LVTKLDHHRGSVT 782
K E P ++C + + +G D + + G +++L+ H V
Sbjct: 310 RPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVD 369
Query: 783 SVKVIQDGNIFITGSQDGTVCTW 805
S++ N F++GS+DGT W
Sbjct: 370 SIQFSNTSNRFVSGSRDGTARIW 392
Score = 34.3 bits (75), Expect = 3.3
Identities = 17/80 (21%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Query: 1167 KLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVK 1226
K+ + ++GH V CV T + ++ +GS DC + +W + +++ +
Sbjct: 174 KMHKRILGHLSSVYCVTFDRTGR-RIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMA 232
Query: 1227 VTGDGTIAVSCAEDKTLIIW 1246
V + T+ + + DK + +W
Sbjct: 233 VNYENTMIAAGSCDKMIRVW 252
Score = 34.3 bits (75), Expect = 3.3
Identities = 18/63 (28%), Positives = 28/63 (44%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + T +GH+ I M V E+ + GS D + VW L T A + H
Sbjct: 208 KIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHS 267
Query: 737 APV 739
A +
Sbjct: 268 ASI 270
>AF052432-1|AAC09328.1| 655|Homo sapiens katanin p80 subunit protein.
Length = 655
Score = 73.3 bits (172), Expect = 6e-12
Identities = 40/154 (25%), Positives = 69/154 (44%), Gaps = 3/154 (1%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
P+ + ++ +L +G G +RVW L ++ TL G +I + F P V SGS
Sbjct: 65 PVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGLKANICSLDFHPYGEFVASGS 124
Query: 1028 EDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH- 1086
+D + +W + Y+GHS A++ L DG+ S+ V +W + +G ++
Sbjct: 125 QDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSE 184
Query: 1087 --SATGPSASIDVTLNMKYAVLSDGDNSVRIWSL 1118
TGP ++ N D ++R W L
Sbjct: 185 FPGHTGPVNVVEFHPNEYLLASGSSDGTIRFWDL 218
Score = 70.9 bits (166), Expect = 3e-11
Identities = 47/233 (20%), Positives = 101/233 (43%), Gaps = 8/233 (3%)
Query: 1022 LVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDS 1081
L+ +G +D V +W + + ++ GH+S ++++ + + ++ ++ ++ VW +++
Sbjct: 35 LLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEA 94
Query: 1082 GIVLHSATGPSA---SIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERIT 1138
+L + G A S+D ++ D ++++W + R H++ +
Sbjct: 95 AKILRTLMGLKANICSLDFHPYGEFVASGSQDTNIKLWDIR---RKGCVFRYRGHSQAVR 151
Query: 1139 CFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWD 1198
C + D + + + + D ++K+W L GK+ GH+ V V N+ + SGS D
Sbjct: 152 CLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFH-PNEYLLASGSSD 210
Query: 1199 CNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLII-WETKR 1250
+ WD+ V V DG S +D + WE +R
Sbjct: 211 GTIRFWDLEKFQVVSRIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPER 263
Score = 68.1 bits (159), Expect = 2e-10
Identities = 36/153 (23%), Positives = 75/153 (49%), Gaps = 1/153 (0%)
Query: 665 QHLVLAPS-AGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
+ L++A S +G ++W + + + T G +I + +++ +GS+DT++ +WD+
Sbjct: 75 EELIVAGSQSGSIRVWDLEAAKILRTLMGLKANICSLDFHPYGEFVASGSQDTNIKLWDI 134
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTS 783
+ H V C+ + + S DD V + L G ++++ H G V
Sbjct: 135 RRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNV 194
Query: 784 VKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV 816
V+ + + +GS DGT+ W++E F ++S +
Sbjct: 195 VEFHPNEYLLASGSSDGTIRFWDLEKFQVVSRI 227
Score = 65.7 bits (153), Expect = 1e-09
Identities = 40/152 (26%), Positives = 69/152 (45%), Gaps = 1/152 (0%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L P G+ + + +LW I V ++GHS ++ C+ + + ++L + ++D +
Sbjct: 111 LDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHT 170
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V +WDL + ++ H PV V N L+ SG D + L +V++++
Sbjct: 171 VKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDGTIRFWDLEKFQVVSRIEGE 230
Query: 778 RGSVTSVKVIQDGNIFITGSQDG-TVCTWNVE 808
G V SV DG +G QD V W E
Sbjct: 231 PGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPE 262
Score = 61.3 bits (142), Expect = 2e-08
Identities = 45/179 (25%), Positives = 76/179 (42%), Gaps = 7/179 (3%)
Query: 1083 IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVS-HAERITCFA 1141
IV H++ S + A D D V +WS+ N + S++ H +
Sbjct: 16 IVAHASNVSSLVLGKASGRLLATGGD-DCRVNLWSI----NKPNCIMSLTGHTSPVESVR 70
Query: 1142 LTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNL 1201
L + +V GS S++VW L+ K+ + L+G + + + V SGS D N+
Sbjct: 71 LNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGLKANICSLDFHPYGEF-VASGSQDTNI 129
Query: 1202 IVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
+WDI V C++ + DG S A+D T+ +W+ G ++ F H
Sbjct: 130 KLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGH 188
Score = 59.7 bits (138), Expect = 8e-08
Identities = 29/94 (30%), Positives = 45/94 (47%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ CL S DG+ AS V++W L+ ++ + GH G + V F PN L+ SGS
Sbjct: 150 VRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSS 209
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDG 1062
D T+ W L +G ++++L DG
Sbjct: 210 DGTIRFWDLEKFQVVSRIEGEPGPVRSVLFNPDG 243
Score = 50.4 bits (115), Expect = 5e-05
Identities = 40/180 (22%), Positives = 74/180 (41%), Gaps = 3/180 (1%)
Query: 750 LVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
L+ +GGDD V + S+ + L H V SV++ + + GSQ G++ W++E
Sbjct: 35 LLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEA 94
Query: 810 FTLLSTVTAGVPIHI--FDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCF 867
+L T+ G+ +I D F+ + D + L + + H V+C
Sbjct: 95 AKILRTL-MGLKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCL 153
Query: 868 CVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTI 927
+ D +A D + L+ L + +++ +LLA+G + TI
Sbjct: 154 RFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDGTI 213
Score = 47.6 bits (108), Expect = 3e-04
Identities = 38/190 (20%), Positives = 78/190 (41%), Gaps = 6/190 (3%)
Query: 978 GQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL 1037
G+L A+G V +W ++ +L GH + V + L+++GS+ ++ VW L
Sbjct: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
Query: 1038 ADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-- 1095
T G + I +L G S + N+ +W + + G S ++
Sbjct: 93 EAAKILRTLMGLKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC 152
Query: 1096 -DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSM 1154
+ + K+ + D++V++W L G + H + + + +GS
Sbjct: 153 LRFSPDGKWLASAADDHTVKLWDLTAGKMMSE---FPGHTGPVNVVEFHPNEYLLASGSS 209
Query: 1155 DMSLKVWKLD 1164
D +++ W L+
Sbjct: 210 DGTIRFWDLE 219
Score = 47.6 bits (108), Expect = 3e-04
Identities = 37/211 (17%), Positives = 81/211 (38%), Gaps = 2/211 (0%)
Query: 678 LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIA 737
LW I + + + GH+ + + + + ++ GS+ S+ VWDL + ++ A
Sbjct: 47 LWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGLKA 106
Query: 738 PVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGS 797
+ + V SG D+ + + + V + H +V ++ DG + +
Sbjct: 107 NICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAA 166
Query: 798 QDGTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHP 856
D TV W++ ++S P+++ + + L + D + +
Sbjct: 167 DDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDGTIRFWDLEKFQVVSR 226
Query: 857 LKRHKAKVKCFCVAHDSSRVAVGCADQ-RIY 886
++ V+ D + GC D R+Y
Sbjct: 227 IEGEPGPVRSVLFNPDGCCLYSGCQDSLRVY 257
Score = 46.8 bits (106), Expect = 6e-04
Identities = 38/213 (17%), Positives = 81/213 (38%), Gaps = 2/213 (0%)
Query: 686 KVHTFKGHSGSILCMCVTRESQYLL-TGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAA 744
K+ H+ ++ + + + S LL TG +D V +W ++ + H +PV V
Sbjct: 12 KLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRL 71
Query: 745 IVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
L+++G ++ + L ++ L + ++ S+ G +GSQD +
Sbjct: 72 NTPEELIVAGSQSGSIRVWDLEAAKILRTLMGLKANICSLDFHPYGEFVASGSQDTNIKL 131
Query: 805 WNVENFTLLSTVTA-GVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAK 863
W++ + + + D +L + D+ + L G + H
Sbjct: 132 WDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGP 191
Query: 864 VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
V + +A G +D I + L Q++
Sbjct: 192 VNVVEFHPNEYLLASGSSDGTIRFWDLEKFQVV 224
Score = 46.4 bits (105), Expect = 8e-04
Identities = 28/103 (27%), Positives = 45/103 (43%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R L+ +P G+ L A +LW + + + F GH+G + + L +GS D
Sbjct: 151 RCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSD 210
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDS 758
++ WDL V ++I PV V + + SG DS
Sbjct: 211 GTIRFWDLEKFQVVSRIEGEPGPVRSVLFNPDGCCLYSGCQDS 253
Score = 40.3 bits (90), Expect = 0.050
Identities = 18/62 (29%), Positives = 33/62 (53%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
P++ +E + L ASG + G +R W L ++ + + G G + V F+P+ + SG
Sbjct: 191 PVNVVEFHPNEYLLASGSSDGTIRFWDLEKFQVVSRIEGEPGPVRSVLFNPDGCCLYSGC 250
Query: 1028 ED 1029
+D
Sbjct: 251 QD 252
>M24194-1|AAA59626.1| 317|Homo sapiens MHC B complex protein 12.3
protein.
Length = 317
Score = 72.5 bits (170), Expect = 1e-11
Identities = 53/218 (24%), Positives = 101/218 (46%), Gaps = 14/218 (6%)
Query: 1045 TYKGHSSAIQTLLMMSD-GRRAMSSDRARNVHVWLV-----DSGIVLHSATGPSASI-DV 1097
T KGH+ + + +S+ R + + +W + + GI + G S + DV
Sbjct: 10 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 69
Query: 1098 TLNM--KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD 1155
++ ++A+ D ++R+W L G + RR V H + + A ++D++ +V+GS D
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTT---RRFVGHTKDVLSVAFSSDNRQIVSGSRD 126
Query: 1156 MSLKVWKLDGG-KLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXX 1213
++K+W G K + HS+ V+CV S + + VS WD + VW++
Sbjct: 127 KTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ V V+ DG++ S +D ++W+ G
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEG 224
Score = 66.1 bits (154), Expect = 9e-10
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 3/183 (1%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
++ GQ + G +LW + + + F GH+ +L + + +++ +++GS D ++
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 130
Query: 720 VWD-LHTLAVKTKILEHIAPVLCVAAIVNRS--LVISGGDDSAVIITSLVDGALVTKLDH 776
+W+ L + H V CV N S +++S G D V + +L + L T
Sbjct: 131 LWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG 190
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
H G + +V V DG++ +G +DG W++ L T+ G I+ + + +L
Sbjct: 191 HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCA 250
Query: 837 LQG 839
G
Sbjct: 251 ATG 253
Score = 65.7 bits (153), Expect = 1e-09
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 10/202 (4%)
Query: 975 SRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPN--NLLVLSGSEDRT 1031
S D + SG +++W L + H ++CV FSPN N +++S D+
Sbjct: 114 SSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL 173
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGP 1091
V VW LA+ + GH+ + T+ + DG S + +W ++ G L++ G
Sbjct: 174 VKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG 233
Query: 1092 SASIDVTLNM-KYAVLSDGDNSVRIWSLAGGDNSEDNRRSV----SHAERITCFAL--TA 1144
+ + +Y + + S++IW L G ++ ++ V S AE C +L +A
Sbjct: 234 DIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSA 293
Query: 1145 DSQHVVTGSMDMSLKVWKLDGG 1166
D Q + G D ++VW++ G
Sbjct: 294 DGQTLFAGYTDNLVRVWQVTIG 315
Score = 64.9 bits (151), Expect = 2e-09
Identities = 63/272 (23%), Positives = 114/272 (41%), Gaps = 19/272 (6%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T+QM R T N + Q + P L SRD + R + + Q
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-----ETNYGIPQ 56
Query: 1002 ATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSD 1061
L GH ++ V S + LSGS D T+ +W L + + + GH+ + ++ SD
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL------NMKYAVLSDG-DNSVR 1114
R+ +S R + + +W G+ ++ S S V+ + ++S G D V+
Sbjct: 117 NRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 1115 IWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVG 1174
+W+LA N + + H + ++ D +G D +W L+ GK L G
Sbjct: 176 VWNLA---NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232
Query: 1175 HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
DI+ + S N+ + + + ++ +WD+
Sbjct: 233 -GDIINALCFS-PNRYWLCAATGP-SIKIWDL 261
Score = 56.8 bits (131), Expect = 5e-07
Identities = 55/252 (21%), Positives = 113/252 (44%), Gaps = 19/252 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+S + +S DGQ SG G +R+W L+T GH + V FS +N ++SGS
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSR 125
Query: 1029 DRTVVVWQ-LADNSPSLTYKGHSSAIQTLLMM--SDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W L ++ + HS + + S +S + V VW + + +
Sbjct: 126 DKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLK 185
Query: 1086 HSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ G + ++ VT++ ++ + G D +W L N + ++ + I
Sbjct: 186 TNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDL----NEGKHLYTLDGGDIINALCF 241
Query: 1143 TADSQHVVTGSMDMSLKVWKLDG----GKLSQVLVGHS---DIVTCVAVSITNKTQVVSG 1195
+ +++ + + S+K+W L+G +L Q ++ S + C +++ + Q +
Sbjct: 242 -SPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 300
Query: 1196 SWDCNLI-VWDI 1206
+ NL+ VW +
Sbjct: 301 GYTDNLVRVWQV 312
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 3/125 (2%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSL 750
+GHS + + ++ + Q+ L+GS D ++ +WDL T + + H VL VA +
Sbjct: 60 RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119
Query: 751 VISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
++SG D + + + + T D H V+ V+ + + I ++ D V WN+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL 179
Query: 808 ENFTL 812
N L
Sbjct: 180 ANCKL 184
Score = 37.1 bits (82), Expect = 0.46
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-----V 1222
L L GH+ VT +A + ++S S D +I+W + + V
Sbjct: 7 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 66
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHV-PLLGFQITSDCARVV 1276
+ V ++ DG A+S + D TL +W+ G F H +L +SD ++V
Sbjct: 67 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
>CR541909-1|CAG46707.1| 317|Homo sapiens GNB2L1 protein.
Length = 317
Score = 72.5 bits (170), Expect = 1e-11
Identities = 53/218 (24%), Positives = 101/218 (46%), Gaps = 14/218 (6%)
Query: 1045 TYKGHSSAIQTLLMMSD-GRRAMSSDRARNVHVWLV-----DSGIVLHSATGPSASI-DV 1097
T KGH+ + + +S+ R + + +W + + GI + G S + DV
Sbjct: 10 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 69
Query: 1098 TLNM--KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD 1155
++ ++A+ D ++R+W L G + RR V H + + A ++D++ +V+GS D
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTT---RRFVGHTKDVLSVAFSSDNRQIVSGSRD 126
Query: 1156 MSLKVWKLDGG-KLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXX 1213
++K+W G K + HS+ V+CV S + + VS WD + VW++
Sbjct: 127 KTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ V V+ DG++ S +D ++W+ G
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEG 224
Score = 66.1 bits (154), Expect = 9e-10
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 3/183 (1%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
++ GQ + G +LW + + + F GH+ +L + + +++ +++GS D ++
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 130
Query: 720 VWD-LHTLAVKTKILEHIAPVLCVAAIVNRS--LVISGGDDSAVIITSLVDGALVTKLDH 776
+W+ L + H V CV N S +++S G D V + +L + L T
Sbjct: 131 LWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG 190
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
H G + +V V DG++ +G +DG W++ L T+ G I+ + + +L
Sbjct: 191 HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCA 250
Query: 837 LQG 839
G
Sbjct: 251 ATG 253
Score = 65.7 bits (153), Expect = 1e-09
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 10/202 (4%)
Query: 975 SRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPN--NLLVLSGSEDRT 1031
S D + SG +++W L + H ++CV FSPN N +++S D+
Sbjct: 114 SSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL 173
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGP 1091
V VW LA+ + GH+ + T+ + DG S + +W ++ G L++ G
Sbjct: 174 VKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG 233
Query: 1092 SASIDVTLNM-KYAVLSDGDNSVRIWSLAGGDNSEDNRRSV----SHAERITCFAL--TA 1144
+ + +Y + + S++IW L G ++ ++ V S AE C +L +A
Sbjct: 234 DIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSA 293
Query: 1145 DSQHVVTGSMDMSLKVWKLDGG 1166
D Q + G D ++VW++ G
Sbjct: 294 DGQTLFAGYTDNLVRVWQVTIG 315
Score = 64.9 bits (151), Expect = 2e-09
Identities = 63/272 (23%), Positives = 114/272 (41%), Gaps = 19/272 (6%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T+QM R T N + Q + P L SRD + R + + Q
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-----ETNYGIPQ 56
Query: 1002 ATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSD 1061
L GH ++ V S + LSGS D T+ +W L + + + GH+ + ++ SD
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL------NMKYAVLSDG-DNSVR 1114
R+ +S R + + +W G+ ++ S S V+ + ++S G D V+
Sbjct: 117 NRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 1115 IWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVG 1174
+W+LA N + + H + ++ D +G D +W L+ GK L G
Sbjct: 176 VWNLA---NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232
Query: 1175 HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
DI+ + S N+ + + + ++ +WD+
Sbjct: 233 -GDIINALCFS-PNRYWLCAATGP-SIKIWDL 261
Score = 56.8 bits (131), Expect = 5e-07
Identities = 55/252 (21%), Positives = 113/252 (44%), Gaps = 19/252 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+S + +S DGQ SG G +R+W L+T GH + V FS +N ++SGS
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSR 125
Query: 1029 DRTVVVWQ-LADNSPSLTYKGHSSAIQTLLMM--SDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W L ++ + HS + + S +S + V VW + + +
Sbjct: 126 DKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLK 185
Query: 1086 HSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ G + ++ VT++ ++ + G D +W L N + ++ + I
Sbjct: 186 TNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDL----NEGKHLYTLDGGDIINALCF 241
Query: 1143 TADSQHVVTGSMDMSLKVWKLDG----GKLSQVLVGHS---DIVTCVAVSITNKTQVVSG 1195
+ +++ + + S+K+W L+G +L Q ++ S + C +++ + Q +
Sbjct: 242 -SPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 300
Query: 1196 SWDCNLI-VWDI 1206
+ NL+ VW +
Sbjct: 301 GYTDNLVRVWQV 312
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 3/125 (2%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSL 750
+GHS + + ++ + Q+ L+GS D ++ +WDL T + + H VL VA +
Sbjct: 60 RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119
Query: 751 VISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
++SG D + + + + T D H V+ V+ + + I ++ D V WN+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL 179
Query: 808 ENFTL 812
N L
Sbjct: 180 ANCKL 184
Score = 37.1 bits (82), Expect = 0.46
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-----V 1222
L L GH+ VT +A + ++S S D +I+W + + V
Sbjct: 7 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 66
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHV-PLLGFQITSDCARVV 1276
+ V ++ DG A+S + D TL +W+ G F H +L +SD ++V
Sbjct: 67 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
>CR456978-1|CAG33259.1| 317|Homo sapiens GNB2L1 protein.
Length = 317
Score = 72.5 bits (170), Expect = 1e-11
Identities = 53/218 (24%), Positives = 101/218 (46%), Gaps = 14/218 (6%)
Query: 1045 TYKGHSSAIQTLLMMSD-GRRAMSSDRARNVHVWLV-----DSGIVLHSATGPSASI-DV 1097
T KGH+ + + +S+ R + + +W + + GI + G S + DV
Sbjct: 10 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 69
Query: 1098 TLNM--KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD 1155
++ ++A+ D ++R+W L G + RR V H + + A ++D++ +V+GS D
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTT---RRFVGHTKDVLSVAFSSDNRQIVSGSRD 126
Query: 1156 MSLKVWKLDGG-KLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXX 1213
++K+W G K + HS+ V+CV S + + VS WD + VW++
Sbjct: 127 KTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ V V+ DG++ S +D ++W+ G
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEG 224
Score = 66.1 bits (154), Expect = 9e-10
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 3/183 (1%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
++ GQ + G +LW + + + F GH+ +L + + +++ +++GS D ++
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 130
Query: 720 VWD-LHTLAVKTKILEHIAPVLCVAAIVNRS--LVISGGDDSAVIITSLVDGALVTKLDH 776
+W+ L + H V CV N S +++S G D V + +L + L T
Sbjct: 131 LWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG 190
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
H G + +V V DG++ +G +DG W++ L T+ G I+ + + +L
Sbjct: 191 HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCA 250
Query: 837 LQG 839
G
Sbjct: 251 ATG 253
Score = 65.7 bits (153), Expect = 1e-09
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 10/202 (4%)
Query: 975 SRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPN--NLLVLSGSEDRT 1031
S D + SG +++W L + H ++CV FSPN N +++S D+
Sbjct: 114 SSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL 173
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGP 1091
V VW LA+ + GH+ + T+ + DG S + +W ++ G L++ G
Sbjct: 174 VKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG 233
Query: 1092 SASIDVTLNM-KYAVLSDGDNSVRIWSLAGGDNSEDNRRSV----SHAERITCFAL--TA 1144
+ + +Y + + S++IW L G ++ ++ V S AE C +L +A
Sbjct: 234 DIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSA 293
Query: 1145 DSQHVVTGSMDMSLKVWKLDGG 1166
D Q + G D ++VW++ G
Sbjct: 294 DGQTLFAGYTDNLVRVWQVTIG 315
Score = 64.9 bits (151), Expect = 2e-09
Identities = 63/272 (23%), Positives = 114/272 (41%), Gaps = 19/272 (6%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T+QM R T N + Q + P L SRD + R + + Q
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-----ETNYGIPQ 56
Query: 1002 ATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSD 1061
L GH ++ V S + LSGS D T+ +W L + + + GH+ + ++ SD
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL------NMKYAVLSDG-DNSVR 1114
R+ +S R + + +W G+ ++ S S V+ + ++S G D V+
Sbjct: 117 NRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 1115 IWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVG 1174
+W+LA N + + H + ++ D +G D +W L+ GK L G
Sbjct: 176 VWNLA---NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232
Query: 1175 HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
DI+ + S N+ + + + ++ +WD+
Sbjct: 233 -GDIINALCFS-PNRYWLCAATGP-SIKIWDL 261
Score = 56.8 bits (131), Expect = 5e-07
Identities = 55/252 (21%), Positives = 113/252 (44%), Gaps = 19/252 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+S + +S DGQ SG G +R+W L+T GH + V FS +N ++SGS
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSR 125
Query: 1029 DRTVVVWQ-LADNSPSLTYKGHSSAIQTLLMM--SDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W L ++ + HS + + S +S + V VW + + +
Sbjct: 126 DKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLK 185
Query: 1086 HSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ G + ++ VT++ ++ + G D +W L N + ++ + I
Sbjct: 186 TNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDL----NEGKHLYTLDGGDIINALCF 241
Query: 1143 TADSQHVVTGSMDMSLKVWKLDG----GKLSQVLVGHS---DIVTCVAVSITNKTQVVSG 1195
+ +++ + + S+K+W L+G +L Q ++ S + C +++ + Q +
Sbjct: 242 -SPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 300
Query: 1196 SWDCNLI-VWDI 1206
+ NL+ VW +
Sbjct: 301 GYTDNLVRVWQV 312
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 3/125 (2%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSL 750
+GHS + + ++ + Q+ L+GS D ++ +WDL T + + H VL VA +
Sbjct: 60 RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119
Query: 751 VISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
++SG D + + + + T D H V+ V+ + + I ++ D V WN+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL 179
Query: 808 ENFTL 812
N L
Sbjct: 180 ANCKL 184
Score = 37.1 bits (82), Expect = 0.46
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-----V 1222
L L GH+ VT +A + ++S S D +I+W + + V
Sbjct: 7 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 66
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHV-PLLGFQITSDCARVV 1276
+ V ++ DG A+S + D TL +W+ G F H +L +SD ++V
Sbjct: 67 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
>BC032006-1|AAH32006.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 72.5 bits (170), Expect = 1e-11
Identities = 53/218 (24%), Positives = 101/218 (46%), Gaps = 14/218 (6%)
Query: 1045 TYKGHSSAIQTLLMMSD-GRRAMSSDRARNVHVWLV-----DSGIVLHSATGPSASI-DV 1097
T KGH+ + + +S+ R + + +W + + GI + G S + DV
Sbjct: 10 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 69
Query: 1098 TLNM--KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD 1155
++ ++A+ D ++R+W L G + RR V H + + A ++D++ +V+GS D
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTT---RRFVGHTKDVLSVAFSSDNRQIVSGSRD 126
Query: 1156 MSLKVWKLDGG-KLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXX 1213
++K+W G K + HS+ V+CV S + + VS WD + VW++
Sbjct: 127 KTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ V V+ DG++ S +D ++W+ G
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEG 224
Score = 66.1 bits (154), Expect = 9e-10
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 3/183 (1%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
++ GQ + G +LW + + + F GH+ +L + + +++ +++GS D ++
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 130
Query: 720 VWD-LHTLAVKTKILEHIAPVLCVAAIVNRS--LVISGGDDSAVIITSLVDGALVTKLDH 776
+W+ L + H V CV N S +++S G D V + +L + L T
Sbjct: 131 LWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG 190
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
H G + +V V DG++ +G +DG W++ L T+ G I+ + + +L
Sbjct: 191 HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCA 250
Query: 837 LQG 839
G
Sbjct: 251 ATG 253
Score = 65.7 bits (153), Expect = 1e-09
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 10/202 (4%)
Query: 975 SRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPN--NLLVLSGSEDRT 1031
S D + SG +++W L + H ++CV FSPN N +++S D+
Sbjct: 114 SSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL 173
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGP 1091
V VW LA+ + GH+ + T+ + DG S + +W ++ G L++ G
Sbjct: 174 VKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG 233
Query: 1092 SASIDVTLNM-KYAVLSDGDNSVRIWSLAGGDNSEDNRRSV----SHAERITCFAL--TA 1144
+ + +Y + + S++IW L G ++ ++ V S AE C +L +A
Sbjct: 234 DIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSA 293
Query: 1145 DSQHVVTGSMDMSLKVWKLDGG 1166
D Q + G D ++VW++ G
Sbjct: 294 DGQTLFAGYTDNLVRVWQVTIG 315
Score = 64.9 bits (151), Expect = 2e-09
Identities = 63/272 (23%), Positives = 114/272 (41%), Gaps = 19/272 (6%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T+QM R T N + Q + P L SRD + R + + Q
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-----ETNYGIPQ 56
Query: 1002 ATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSD 1061
L GH ++ V S + LSGS D T+ +W L + + + GH+ + ++ SD
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL------NMKYAVLSDG-DNSVR 1114
R+ +S R + + +W G+ ++ S S V+ + ++S G D V+
Sbjct: 117 NRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 1115 IWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVG 1174
+W+LA N + + H + ++ D +G D +W L+ GK L G
Sbjct: 176 VWNLA---NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232
Query: 1175 HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
DI+ + S N+ + + + ++ +WD+
Sbjct: 233 -GDIINALCFS-PNRYWLCAATGP-SIKIWDL 261
Score = 56.8 bits (131), Expect = 5e-07
Identities = 55/252 (21%), Positives = 113/252 (44%), Gaps = 19/252 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+S + +S DGQ SG G +R+W L+T GH + V FS +N ++SGS
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSR 125
Query: 1029 DRTVVVWQ-LADNSPSLTYKGHSSAIQTLLMM--SDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W L ++ + HS + + S +S + V VW + + +
Sbjct: 126 DKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLK 185
Query: 1086 HSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ G + ++ VT++ ++ + G D +W L N + ++ + I
Sbjct: 186 TNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDL----NEGKHLYTLDGGDIINALCF 241
Query: 1143 TADSQHVVTGSMDMSLKVWKLDG----GKLSQVLVGHS---DIVTCVAVSITNKTQVVSG 1195
+ +++ + + S+K+W L+G +L Q ++ S + C +++ + Q +
Sbjct: 242 -SPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 300
Query: 1196 SWDCNLI-VWDI 1206
+ NL+ VW +
Sbjct: 301 GYTDNLVRVWQV 312
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 3/125 (2%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSL 750
+GHS + + ++ + Q+ L+GS D ++ +WDL T + + H VL VA +
Sbjct: 60 RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119
Query: 751 VISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
++SG D + + + + T D H V+ V+ + + I ++ D V WN+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL 179
Query: 808 ENFTL 812
N L
Sbjct: 180 ANCKL 184
Score = 37.1 bits (82), Expect = 0.46
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-----V 1222
L L GH+ VT +A + ++S S D +I+W + + V
Sbjct: 7 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 66
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHV-PLLGFQITSDCARVV 1276
+ V ++ DG A+S + D TL +W+ G F H +L +SD ++V
Sbjct: 67 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
>BC021993-1|AAH21993.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 72.5 bits (170), Expect = 1e-11
Identities = 53/218 (24%), Positives = 101/218 (46%), Gaps = 14/218 (6%)
Query: 1045 TYKGHSSAIQTLLMMSD-GRRAMSSDRARNVHVWLV-----DSGIVLHSATGPSASI-DV 1097
T KGH+ + + +S+ R + + +W + + GI + G S + DV
Sbjct: 10 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 69
Query: 1098 TLNM--KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD 1155
++ ++A+ D ++R+W L G + RR V H + + A ++D++ +V+GS D
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTT---RRFVGHTKDVLSVAFSSDNRQIVSGSRD 126
Query: 1156 MSLKVWKLDGG-KLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXX 1213
++K+W G K + HS+ V+CV S + + VS WD + VW++
Sbjct: 127 KTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ V V+ DG++ S +D ++W+ G
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEG 224
Score = 66.1 bits (154), Expect = 9e-10
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 3/183 (1%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
++ GQ + G +LW + + + F GH+ +L + + +++ +++GS D ++
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 130
Query: 720 VWD-LHTLAVKTKILEHIAPVLCVAAIVNRS--LVISGGDDSAVIITSLVDGALVTKLDH 776
+W+ L + H V CV N S +++S G D V + +L + L T
Sbjct: 131 LWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG 190
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
H G + +V V DG++ +G +DG W++ L T+ G I+ + + +L
Sbjct: 191 HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCA 250
Query: 837 LQG 839
G
Sbjct: 251 ATG 253
Score = 65.7 bits (153), Expect = 1e-09
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 10/202 (4%)
Query: 975 SRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPN--NLLVLSGSEDRT 1031
S D + SG +++W L + H ++CV FSPN N +++S D+
Sbjct: 114 SSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL 173
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGP 1091
V VW LA+ + GH+ + T+ + DG S + +W ++ G L++ G
Sbjct: 174 VKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG 233
Query: 1092 SASIDVTLNM-KYAVLSDGDNSVRIWSLAGGDNSEDNRRSV----SHAERITCFAL--TA 1144
+ + +Y + + S++IW L G ++ ++ V S AE C +L +A
Sbjct: 234 DIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSA 293
Query: 1145 DSQHVVTGSMDMSLKVWKLDGG 1166
D Q + G D ++VW++ G
Sbjct: 294 DGQTLFAGYTDNLVRVWQVTIG 315
Score = 64.9 bits (151), Expect = 2e-09
Identities = 63/272 (23%), Positives = 114/272 (41%), Gaps = 19/272 (6%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T+QM R T N + Q + P L SRD + R + + Q
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-----ETNYGIPQ 56
Query: 1002 ATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSD 1061
L GH ++ V S + LSGS D T+ +W L + + + GH+ + ++ SD
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL------NMKYAVLSDG-DNSVR 1114
R+ +S R + + +W G+ ++ S S V+ + ++S G D V+
Sbjct: 117 NRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 1115 IWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVG 1174
+W+LA N + + H + ++ D +G D +W L+ GK L G
Sbjct: 176 VWNLA---NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232
Query: 1175 HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
DI+ + S N+ + + + ++ +WD+
Sbjct: 233 -GDIINALCFS-PNRYWLCAATGP-SIKIWDL 261
Score = 56.8 bits (131), Expect = 5e-07
Identities = 55/252 (21%), Positives = 113/252 (44%), Gaps = 19/252 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+S + +S DGQ SG G +R+W L+T GH + V FS +N ++SGS
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSR 125
Query: 1029 DRTVVVWQ-LADNSPSLTYKGHSSAIQTLLMM--SDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W L ++ + HS + + S +S + V VW + + +
Sbjct: 126 DKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLK 185
Query: 1086 HSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ G + ++ VT++ ++ + G D +W L N + ++ + I
Sbjct: 186 TNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDL----NEGKHLYTLDGGDIINALCF 241
Query: 1143 TADSQHVVTGSMDMSLKVWKLDG----GKLSQVLVGHS---DIVTCVAVSITNKTQVVSG 1195
+ +++ + + S+K+W L+G +L Q ++ S + C +++ + Q +
Sbjct: 242 -SPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 300
Query: 1196 SWDCNLI-VWDI 1206
+ NL+ VW +
Sbjct: 301 GYTDNLVRVWQV 312
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 3/125 (2%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSL 750
+GHS + + ++ + Q+ L+GS D ++ +WDL T + + H VL VA +
Sbjct: 60 RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119
Query: 751 VISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
++SG D + + + + T D H V+ V+ + + I ++ D V WN+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL 179
Query: 808 ENFTL 812
N L
Sbjct: 180 ANCKL 184
Score = 37.1 bits (82), Expect = 0.46
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-----V 1222
L L GH+ VT +A + ++S S D +I+W + + V
Sbjct: 7 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 66
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHV-PLLGFQITSDCARVV 1276
+ V ++ DG A+S + D TL +W+ G F H +L +SD ++V
Sbjct: 67 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
>BC019362-1|AAH19362.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 72.5 bits (170), Expect = 1e-11
Identities = 53/218 (24%), Positives = 101/218 (46%), Gaps = 14/218 (6%)
Query: 1045 TYKGHSSAIQTLLMMSD-GRRAMSSDRARNVHVWLV-----DSGIVLHSATGPSASI-DV 1097
T KGH+ + + +S+ R + + +W + + GI + G S + DV
Sbjct: 10 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 69
Query: 1098 TLNM--KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD 1155
++ ++A+ D ++R+W L G + RR V H + + A ++D++ +V+GS D
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTT---RRFVGHTKDVLSVAFSSDNRQIVSGSRD 126
Query: 1156 MSLKVWKLDGG-KLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXX 1213
++K+W G K + HS+ V+CV S + + VS WD + VW++
Sbjct: 127 KTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ V V+ DG++ S +D ++W+ G
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEG 224
Score = 66.1 bits (154), Expect = 9e-10
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 3/183 (1%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
++ GQ + G +LW + + + F GH+ +L + + +++ +++GS D ++
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 130
Query: 720 VWD-LHTLAVKTKILEHIAPVLCVAAIVNRS--LVISGGDDSAVIITSLVDGALVTKLDH 776
+W+ L + H V CV N S +++S G D V + +L + L T
Sbjct: 131 LWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG 190
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
H G + +V V DG++ +G +DG W++ L T+ G I+ + + +L
Sbjct: 191 HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCA 250
Query: 837 LQG 839
G
Sbjct: 251 ATG 253
Score = 65.7 bits (153), Expect = 1e-09
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 10/202 (4%)
Query: 975 SRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPN--NLLVLSGSEDRT 1031
S D + SG +++W L + H ++CV FSPN N +++S D+
Sbjct: 114 SSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL 173
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGP 1091
V VW LA+ + GH+ + T+ + DG S + +W ++ G L++ G
Sbjct: 174 VKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG 233
Query: 1092 SASIDVTLNM-KYAVLSDGDNSVRIWSLAGGDNSEDNRRSV----SHAERITCFAL--TA 1144
+ + +Y + + S++IW L G ++ ++ V S AE C +L +A
Sbjct: 234 DIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSA 293
Query: 1145 DSQHVVTGSMDMSLKVWKLDGG 1166
D Q + G D ++VW++ G
Sbjct: 294 DGQTLFAGYTDNLVRVWQVTIG 315
Score = 64.9 bits (151), Expect = 2e-09
Identities = 63/272 (23%), Positives = 114/272 (41%), Gaps = 19/272 (6%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T+QM R T N + Q + P L SRD + R + + Q
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-----ETNYGIPQ 56
Query: 1002 ATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSD 1061
L GH ++ V S + LSGS D T+ +W L + + + GH+ + ++ SD
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL------NMKYAVLSDG-DNSVR 1114
R+ +S R + + +W G+ ++ S S V+ + ++S G D V+
Sbjct: 117 NRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 1115 IWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVG 1174
+W+LA N + + H + ++ D +G D +W L+ GK L G
Sbjct: 176 VWNLA---NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232
Query: 1175 HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
DI+ + S N+ + + + ++ +WD+
Sbjct: 233 -GDIINALCFS-PNRYWLCAATGP-SIKIWDL 261
Score = 56.8 bits (131), Expect = 5e-07
Identities = 55/252 (21%), Positives = 113/252 (44%), Gaps = 19/252 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+S + +S DGQ SG G +R+W L+T GH + V FS +N ++SGS
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSR 125
Query: 1029 DRTVVVWQ-LADNSPSLTYKGHSSAIQTLLMM--SDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W L ++ + HS + + S +S + V VW + + +
Sbjct: 126 DKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLK 185
Query: 1086 HSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ G + ++ VT++ ++ + G D +W L N + ++ + I
Sbjct: 186 TNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDL----NEGKHLYTLDGGDIINALCF 241
Query: 1143 TADSQHVVTGSMDMSLKVWKLDG----GKLSQVLVGHS---DIVTCVAVSITNKTQVVSG 1195
+ +++ + + S+K+W L+G +L Q ++ S + C +++ + Q +
Sbjct: 242 -SPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 300
Query: 1196 SWDCNLI-VWDI 1206
+ NL+ VW +
Sbjct: 301 GYTDNLVRVWQV 312
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 3/125 (2%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSL 750
+GHS + + ++ + Q+ L+GS D ++ +WDL T + + H VL VA +
Sbjct: 60 RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119
Query: 751 VISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
++SG D + + + + T D H V+ V+ + + I ++ D V WN+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL 179
Query: 808 ENFTL 812
N L
Sbjct: 180 ANCKL 184
Score = 37.1 bits (82), Expect = 0.46
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-----V 1222
L L GH+ VT +A + ++S S D +I+W + + V
Sbjct: 7 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 66
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHV-PLLGFQITSDCARVV 1276
+ V ++ DG A+S + D TL +W+ G F H +L +SD ++V
Sbjct: 67 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
>BC019093-1|AAH19093.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 72.5 bits (170), Expect = 1e-11
Identities = 53/218 (24%), Positives = 101/218 (46%), Gaps = 14/218 (6%)
Query: 1045 TYKGHSSAIQTLLMMSD-GRRAMSSDRARNVHVWLV-----DSGIVLHSATGPSASI-DV 1097
T KGH+ + + +S+ R + + +W + + GI + G S + DV
Sbjct: 10 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 69
Query: 1098 TLNM--KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD 1155
++ ++A+ D ++R+W L G + RR V H + + A ++D++ +V+GS D
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTT---RRFVGHTKDVLSVAFSSDNRQIVSGSRD 126
Query: 1156 MSLKVWKLDGG-KLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXX 1213
++K+W G K + HS+ V+CV S + + VS WD + VW++
Sbjct: 127 KTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ V V+ DG++ S +D ++W+ G
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEG 224
Score = 66.1 bits (154), Expect = 9e-10
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 3/183 (1%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
++ GQ + G +LW + + + F GH+ +L + + +++ +++GS D ++
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 130
Query: 720 VWD-LHTLAVKTKILEHIAPVLCVAAIVNRS--LVISGGDDSAVIITSLVDGALVTKLDH 776
+W+ L + H V CV N S +++S G D V + +L + L T
Sbjct: 131 LWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG 190
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
H G + +V V DG++ +G +DG W++ L T+ G I+ + + +L
Sbjct: 191 HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCA 250
Query: 837 LQG 839
G
Sbjct: 251 ATG 253
Score = 65.7 bits (153), Expect = 1e-09
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 10/202 (4%)
Query: 975 SRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPN--NLLVLSGSEDRT 1031
S D + SG +++W L + H ++CV FSPN N +++S D+
Sbjct: 114 SSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL 173
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGP 1091
V VW LA+ + GH+ + T+ + DG S + +W ++ G L++ G
Sbjct: 174 VKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG 233
Query: 1092 SASIDVTLNM-KYAVLSDGDNSVRIWSLAGGDNSEDNRRSV----SHAERITCFAL--TA 1144
+ + +Y + + S++IW L G ++ ++ V S AE C +L +A
Sbjct: 234 DIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSA 293
Query: 1145 DSQHVVTGSMDMSLKVWKLDGG 1166
D Q + G D ++VW++ G
Sbjct: 294 DGQTLFAGYTDNLVRVWQVTIG 315
Score = 64.9 bits (151), Expect = 2e-09
Identities = 63/272 (23%), Positives = 114/272 (41%), Gaps = 19/272 (6%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T+QM R T N + Q + P L SRD + R + + Q
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-----ETNYGIPQ 56
Query: 1002 ATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSD 1061
L GH ++ V S + LSGS D T+ +W L + + + GH+ + ++ SD
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL------NMKYAVLSDG-DNSVR 1114
R+ +S R + + +W G+ ++ S S V+ + ++S G D V+
Sbjct: 117 NRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 1115 IWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVG 1174
+W+LA N + + H + ++ D +G D +W L+ GK L G
Sbjct: 176 VWNLA---NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232
Query: 1175 HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
DI+ + S N+ + + + ++ +WD+
Sbjct: 233 -GDIINALCFS-PNRYWLCAATGP-SIKIWDL 261
Score = 56.8 bits (131), Expect = 5e-07
Identities = 55/252 (21%), Positives = 113/252 (44%), Gaps = 19/252 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+S + +S DGQ SG G +R+W L+T GH + V FS +N ++SGS
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSR 125
Query: 1029 DRTVVVWQ-LADNSPSLTYKGHSSAIQTLLMM--SDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W L ++ + HS + + S +S + V VW + + +
Sbjct: 126 DKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLK 185
Query: 1086 HSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ G + ++ VT++ ++ + G D +W L N + ++ + I
Sbjct: 186 TNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDL----NEGKHLYTLDGGDIINALCF 241
Query: 1143 TADSQHVVTGSMDMSLKVWKLDG----GKLSQVLVGHS---DIVTCVAVSITNKTQVVSG 1195
+ +++ + + S+K+W L+G +L Q ++ S + C +++ + Q +
Sbjct: 242 -SPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 300
Query: 1196 SWDCNLI-VWDI 1206
+ NL+ VW +
Sbjct: 301 GYTDNLVRVWQV 312
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 3/125 (2%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSL 750
+GHS + + ++ + Q+ L+GS D ++ +WDL T + + H VL VA +
Sbjct: 60 RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119
Query: 751 VISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
++SG D + + + + T D H V+ V+ + + I ++ D V WN+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL 179
Query: 808 ENFTL 812
N L
Sbjct: 180 ANCKL 184
Score = 37.1 bits (82), Expect = 0.46
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-----V 1222
L L GH+ VT +A + ++S S D +I+W + + V
Sbjct: 7 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 66
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHV-PLLGFQITSDCARVV 1276
+ V ++ DG A+S + D TL +W+ G F H +L +SD ++V
Sbjct: 67 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
>BC017287-1|AAH17287.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 72.5 bits (170), Expect = 1e-11
Identities = 53/218 (24%), Positives = 101/218 (46%), Gaps = 14/218 (6%)
Query: 1045 TYKGHSSAIQTLLMMSD-GRRAMSSDRARNVHVWLV-----DSGIVLHSATGPSASI-DV 1097
T KGH+ + + +S+ R + + +W + + GI + G S + DV
Sbjct: 10 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 69
Query: 1098 TLNM--KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD 1155
++ ++A+ D ++R+W L G + RR V H + + A ++D++ +V+GS D
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTT---RRFVGHTKDVLSVAFSSDNRQIVSGSRD 126
Query: 1156 MSLKVWKLDGG-KLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXX 1213
++K+W G K + HS+ V+CV S + + VS WD + VW++
Sbjct: 127 KTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ V V+ DG++ S +D ++W+ G
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEG 224
Score = 66.1 bits (154), Expect = 9e-10
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 3/183 (1%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
++ GQ + G +LW + + + F GH+ +L + + +++ +++GS D ++
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 130
Query: 720 VWD-LHTLAVKTKILEHIAPVLCVAAIVNRS--LVISGGDDSAVIITSLVDGALVTKLDH 776
+W+ L + H V CV N S +++S G D V + +L + L T
Sbjct: 131 LWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG 190
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
H G + +V V DG++ +G +DG W++ L T+ G I+ + + +L
Sbjct: 191 HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCA 250
Query: 837 LQG 839
G
Sbjct: 251 ATG 253
Score = 65.7 bits (153), Expect = 1e-09
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 10/202 (4%)
Query: 975 SRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPN--NLLVLSGSEDRT 1031
S D + SG +++W L + H ++CV FSPN N +++S D+
Sbjct: 114 SSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL 173
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGP 1091
V VW LA+ + GH+ + T+ + DG S + +W ++ G L++ G
Sbjct: 174 VKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG 233
Query: 1092 SASIDVTLNM-KYAVLSDGDNSVRIWSLAGGDNSEDNRRSV----SHAERITCFAL--TA 1144
+ + +Y + + S++IW L G ++ ++ V S AE C +L +A
Sbjct: 234 DIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSA 293
Query: 1145 DSQHVVTGSMDMSLKVWKLDGG 1166
D Q + G D ++VW++ G
Sbjct: 294 DGQTLFAGYTDNLVRVWQVTIG 315
Score = 64.9 bits (151), Expect = 2e-09
Identities = 63/272 (23%), Positives = 114/272 (41%), Gaps = 19/272 (6%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T+QM R T N + Q + P L SRD + R + + Q
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-----ETNYGIPQ 56
Query: 1002 ATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSD 1061
L GH ++ V S + LSGS D T+ +W L + + + GH+ + ++ SD
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL------NMKYAVLSDG-DNSVR 1114
R+ +S R + + +W G+ ++ S S V+ + ++S G D V+
Sbjct: 117 NRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 1115 IWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVG 1174
+W+LA N + + H + ++ D +G D +W L+ GK L G
Sbjct: 176 VWNLA---NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232
Query: 1175 HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
DI+ + S N+ + + + ++ +WD+
Sbjct: 233 -GDIINALCFS-PNRYWLCAATGP-SIKIWDL 261
Score = 56.8 bits (131), Expect = 5e-07
Identities = 55/252 (21%), Positives = 113/252 (44%), Gaps = 19/252 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+S + +S DGQ SG G +R+W L+T GH + V FS +N ++SGS
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSR 125
Query: 1029 DRTVVVWQ-LADNSPSLTYKGHSSAIQTLLMM--SDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W L ++ + HS + + S +S + V VW + + +
Sbjct: 126 DKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLK 185
Query: 1086 HSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ G + ++ VT++ ++ + G D +W L N + ++ + I
Sbjct: 186 TNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDL----NEGKHLYTLDGGDIINALCF 241
Query: 1143 TADSQHVVTGSMDMSLKVWKLDG----GKLSQVLVGHS---DIVTCVAVSITNKTQVVSG 1195
+ +++ + + S+K+W L+G +L Q ++ S + C +++ + Q +
Sbjct: 242 -SPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 300
Query: 1196 SWDCNLI-VWDI 1206
+ NL+ VW +
Sbjct: 301 GYTDNLVRVWQV 312
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 3/125 (2%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSL 750
+GHS + + ++ + Q+ L+GS D ++ +WDL T + + H VL VA +
Sbjct: 60 RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119
Query: 751 VISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
++SG D + + + + T D H V+ V+ + + I ++ D V WN+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL 179
Query: 808 ENFTL 812
N L
Sbjct: 180 ANCKL 184
Score = 37.1 bits (82), Expect = 0.46
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-----V 1222
L L GH+ VT +A + ++S S D +I+W + + V
Sbjct: 7 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 66
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHV-PLLGFQITSDCARVV 1276
+ V ++ DG A+S + D TL +W+ G F H +L +SD ++V
Sbjct: 67 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
>BC014788-1|AAH14788.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 72.5 bits (170), Expect = 1e-11
Identities = 53/218 (24%), Positives = 101/218 (46%), Gaps = 14/218 (6%)
Query: 1045 TYKGHSSAIQTLLMMSD-GRRAMSSDRARNVHVWLV-----DSGIVLHSATGPSASI-DV 1097
T KGH+ + + +S+ R + + +W + + GI + G S + DV
Sbjct: 10 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 69
Query: 1098 TLNM--KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD 1155
++ ++A+ D ++R+W L G + RR V H + + A ++D++ +V+GS D
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTT---RRFVGHTKDVLSVAFSSDNRQIVSGSRD 126
Query: 1156 MSLKVWKLDGG-KLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXX 1213
++K+W G K + HS+ V+CV S + + VS WD + VW++
Sbjct: 127 KTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ V V+ DG++ S +D ++W+ G
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEG 224
Score = 66.1 bits (154), Expect = 9e-10
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 3/183 (1%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
++ GQ + G +LW + + + F GH+ +L + + +++ +++GS D ++
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 130
Query: 720 VWD-LHTLAVKTKILEHIAPVLCVAAIVNRS--LVISGGDDSAVIITSLVDGALVTKLDH 776
+W+ L + H V CV N S +++S G D V + +L + L T
Sbjct: 131 LWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG 190
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
H G + +V V DG++ +G +DG W++ L T+ G I+ + + +L
Sbjct: 191 HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCA 250
Query: 837 LQG 839
G
Sbjct: 251 ATG 253
Score = 65.7 bits (153), Expect = 1e-09
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 10/202 (4%)
Query: 975 SRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPN--NLLVLSGSEDRT 1031
S D + SG +++W L + H ++CV FSPN N +++S D+
Sbjct: 114 SSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL 173
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGP 1091
V VW LA+ + GH+ + T+ + DG S + +W ++ G L++ G
Sbjct: 174 VKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG 233
Query: 1092 SASIDVTLNM-KYAVLSDGDNSVRIWSLAGGDNSEDNRRSV----SHAERITCFAL--TA 1144
+ + +Y + + S++IW L G ++ ++ V S AE C +L +A
Sbjct: 234 DIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSA 293
Query: 1145 DSQHVVTGSMDMSLKVWKLDGG 1166
D Q + G D ++VW++ G
Sbjct: 294 DGQTLFAGYTDNLVRVWQVTIG 315
Score = 64.9 bits (151), Expect = 2e-09
Identities = 63/272 (23%), Positives = 114/272 (41%), Gaps = 19/272 (6%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T+QM R T N + Q + P L SRD + R + + Q
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-----ETNYGIPQ 56
Query: 1002 ATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSD 1061
L GH ++ V S + LSGS D T+ +W L + + + GH+ + ++ SD
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL------NMKYAVLSDG-DNSVR 1114
R+ +S R + + +W G+ ++ S S V+ + ++S G D V+
Sbjct: 117 NRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 1115 IWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVG 1174
+W+LA N + + H + ++ D +G D +W L+ GK L G
Sbjct: 176 VWNLA---NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232
Query: 1175 HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
DI+ + S N+ + + + ++ +WD+
Sbjct: 233 -GDIINALCFS-PNRYWLCAATGP-SIKIWDL 261
Score = 56.8 bits (131), Expect = 5e-07
Identities = 55/252 (21%), Positives = 113/252 (44%), Gaps = 19/252 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+S + +S DGQ SG G +R+W L+T GH + V FS +N ++SGS
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSR 125
Query: 1029 DRTVVVWQ-LADNSPSLTYKGHSSAIQTLLMM--SDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W L ++ + HS + + S +S + V VW + + +
Sbjct: 126 DKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLK 185
Query: 1086 HSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ G + ++ VT++ ++ + G D +W L N + ++ + I
Sbjct: 186 TNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDL----NEGKHLYTLDGGDIINALCF 241
Query: 1143 TADSQHVVTGSMDMSLKVWKLDG----GKLSQVLVGHS---DIVTCVAVSITNKTQVVSG 1195
+ +++ + + S+K+W L+G +L Q ++ S + C +++ + Q +
Sbjct: 242 -SPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 300
Query: 1196 SWDCNLI-VWDI 1206
+ NL+ VW +
Sbjct: 301 GYTDNLVRVWQV 312
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 3/125 (2%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSL 750
+GHS + + ++ + Q+ L+GS D ++ +WDL T + + H VL VA +
Sbjct: 60 RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119
Query: 751 VISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
++SG D + + + + T D H V+ V+ + + I ++ D V WN+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL 179
Query: 808 ENFTL 812
N L
Sbjct: 180 ANCKL 184
Score = 37.1 bits (82), Expect = 0.46
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-----V 1222
L L GH+ VT +A + ++S S D +I+W + + V
Sbjct: 7 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 66
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHV-PLLGFQITSDCARVV 1276
+ V ++ DG A+S + D TL +W+ G F H +L +SD ++V
Sbjct: 67 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
>BC014256-1|AAH14256.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 72.5 bits (170), Expect = 1e-11
Identities = 53/218 (24%), Positives = 101/218 (46%), Gaps = 14/218 (6%)
Query: 1045 TYKGHSSAIQTLLMMSD-GRRAMSSDRARNVHVWLV-----DSGIVLHSATGPSASI-DV 1097
T KGH+ + + +S+ R + + +W + + GI + G S + DV
Sbjct: 10 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 69
Query: 1098 TLNM--KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD 1155
++ ++A+ D ++R+W L G + RR V H + + A ++D++ +V+GS D
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTT---RRFVGHTKDVLSVAFSSDNRQIVSGSRD 126
Query: 1156 MSLKVWKLDGG-KLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXX 1213
++K+W G K + HS+ V+CV S + + VS WD + VW++
Sbjct: 127 KTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ V V+ DG++ S +D ++W+ G
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEG 224
Score = 66.1 bits (154), Expect = 9e-10
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 3/183 (1%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
++ GQ + G +LW + + + F GH+ +L + + +++ +++GS D ++
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 130
Query: 720 VWD-LHTLAVKTKILEHIAPVLCVAAIVNRS--LVISGGDDSAVIITSLVDGALVTKLDH 776
+W+ L + H V CV N S +++S G D V + +L + L T
Sbjct: 131 LWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG 190
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
H G + +V V DG++ +G +DG W++ L T+ G I+ + + +L
Sbjct: 191 HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCA 250
Query: 837 LQG 839
G
Sbjct: 251 ATG 253
Score = 65.7 bits (153), Expect = 1e-09
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 10/202 (4%)
Query: 975 SRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPN--NLLVLSGSEDRT 1031
S D + SG +++W L + H ++CV FSPN N +++S D+
Sbjct: 114 SSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL 173
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGP 1091
V VW LA+ + GH+ + T+ + DG S + +W ++ G L++ G
Sbjct: 174 VKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG 233
Query: 1092 SASIDVTLNM-KYAVLSDGDNSVRIWSLAGGDNSEDNRRSV----SHAERITCFAL--TA 1144
+ + +Y + + S++IW L G ++ ++ V S AE C +L +A
Sbjct: 234 DIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSA 293
Query: 1145 DSQHVVTGSMDMSLKVWKLDGG 1166
D Q + G D ++VW++ G
Sbjct: 294 DGQTLFAGYTDNLVRVWQVTIG 315
Score = 64.9 bits (151), Expect = 2e-09
Identities = 63/272 (23%), Positives = 114/272 (41%), Gaps = 19/272 (6%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T+QM R T N + Q + P L SRD + R + + Q
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-----ETNYGIPQ 56
Query: 1002 ATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSD 1061
L GH ++ V S + LSGS D T+ +W L + + + GH+ + ++ SD
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL------NMKYAVLSDG-DNSVR 1114
R+ +S R + + +W G+ ++ S S V+ + ++S G D V+
Sbjct: 117 NRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 1115 IWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVG 1174
+W+LA N + + H + ++ D +G D +W L+ GK L G
Sbjct: 176 VWNLA---NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232
Query: 1175 HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
DI+ + S N+ + + + ++ +WD+
Sbjct: 233 -GDIINALCFS-PNRYWLCAATGP-SIKIWDL 261
Score = 56.8 bits (131), Expect = 5e-07
Identities = 55/252 (21%), Positives = 113/252 (44%), Gaps = 19/252 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+S + +S DGQ SG G +R+W L+T GH + V FS +N ++SGS
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSR 125
Query: 1029 DRTVVVWQ-LADNSPSLTYKGHSSAIQTLLMM--SDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W L ++ + HS + + S +S + V VW + + +
Sbjct: 126 DKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLK 185
Query: 1086 HSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ G + ++ VT++ ++ + G D +W L N + ++ + I
Sbjct: 186 TNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDL----NEGKHLYTLDGGDIINALCF 241
Query: 1143 TADSQHVVTGSMDMSLKVWKLDG----GKLSQVLVGHS---DIVTCVAVSITNKTQVVSG 1195
+ +++ + + S+K+W L+G +L Q ++ S + C +++ + Q +
Sbjct: 242 -SPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 300
Query: 1196 SWDCNLI-VWDI 1206
+ NL+ VW +
Sbjct: 301 GYTDNLVRVWQV 312
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 3/125 (2%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSL 750
+GHS + + ++ + Q+ L+GS D ++ +WDL T + + H VL VA +
Sbjct: 60 RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119
Query: 751 VISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
++SG D + + + + T D H V+ V+ + + I ++ D V WN+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL 179
Query: 808 ENFTL 812
N L
Sbjct: 180 ANCKL 184
Score = 37.1 bits (82), Expect = 0.46
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-----V 1222
L L GH+ VT +A + ++S S D +I+W + + V
Sbjct: 7 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 66
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHV-PLLGFQITSDCARVV 1276
+ V ++ DG A+S + D TL +W+ G F H +L +SD ++V
Sbjct: 67 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
>BC010119-1|AAH10119.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 72.5 bits (170), Expect = 1e-11
Identities = 53/218 (24%), Positives = 101/218 (46%), Gaps = 14/218 (6%)
Query: 1045 TYKGHSSAIQTLLMMSD-GRRAMSSDRARNVHVWLV-----DSGIVLHSATGPSASI-DV 1097
T KGH+ + + +S+ R + + +W + + GI + G S + DV
Sbjct: 10 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 69
Query: 1098 TLNM--KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD 1155
++ ++A+ D ++R+W L G + RR V H + + A ++D++ +V+GS D
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTT---RRFVGHTKDVLSVAFSSDNRQIVSGSRD 126
Query: 1156 MSLKVWKLDGG-KLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXX 1213
++K+W G K + HS+ V+CV S + + VS WD + VW++
Sbjct: 127 KTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ V V+ DG++ S +D ++W+ G
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEG 224
Score = 66.1 bits (154), Expect = 9e-10
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 3/183 (1%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
++ GQ + G +LW + + + F GH+ +L + + +++ +++GS D ++
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 130
Query: 720 VWD-LHTLAVKTKILEHIAPVLCVAAIVNRS--LVISGGDDSAVIITSLVDGALVTKLDH 776
+W+ L + H V CV N S +++S G D V + +L + L T
Sbjct: 131 LWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG 190
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
H G + +V V DG++ +G +DG W++ L T+ G I+ + + +L
Sbjct: 191 HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCA 250
Query: 837 LQG 839
G
Sbjct: 251 ATG 253
Score = 65.7 bits (153), Expect = 1e-09
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 10/202 (4%)
Query: 975 SRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPN--NLLVLSGSEDRT 1031
S D + SG +++W L + H ++CV FSPN N +++S D+
Sbjct: 114 SSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL 173
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGP 1091
V VW LA+ + GH+ + T+ + DG S + +W ++ G L++ G
Sbjct: 174 VKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG 233
Query: 1092 SASIDVTLNM-KYAVLSDGDNSVRIWSLAGGDNSEDNRRSV----SHAERITCFAL--TA 1144
+ + +Y + + S++IW L G ++ ++ V S AE C +L +A
Sbjct: 234 DIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSA 293
Query: 1145 DSQHVVTGSMDMSLKVWKLDGG 1166
D Q + G D ++VW++ G
Sbjct: 294 DGQTLFAGYTDNLVRVWQVTIG 315
Score = 64.9 bits (151), Expect = 2e-09
Identities = 63/272 (23%), Positives = 114/272 (41%), Gaps = 19/272 (6%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T+QM R T N + Q + P L SRD + R + + Q
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-----ETNYGIPQ 56
Query: 1002 ATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSD 1061
L GH ++ V S + LSGS D T+ +W L + + + GH+ + ++ SD
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL------NMKYAVLSDG-DNSVR 1114
R+ +S R + + +W G+ ++ S S V+ + ++S G D V+
Sbjct: 117 NRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 1115 IWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVG 1174
+W+LA N + + H + ++ D +G D +W L+ GK L G
Sbjct: 176 VWNLA---NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232
Query: 1175 HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
DI+ + S N+ + + + ++ +WD+
Sbjct: 233 -GDIINALCFS-PNRYWLCAATGP-SIKIWDL 261
Score = 56.8 bits (131), Expect = 5e-07
Identities = 55/252 (21%), Positives = 113/252 (44%), Gaps = 19/252 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+S + +S DGQ SG G +R+W L+T GH + V FS +N ++SGS
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSR 125
Query: 1029 DRTVVVWQ-LADNSPSLTYKGHSSAIQTLLMM--SDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W L ++ + HS + + S +S + V VW + + +
Sbjct: 126 DKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLK 185
Query: 1086 HSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ G + ++ VT++ ++ + G D +W L N + ++ + I
Sbjct: 186 TNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDL----NEGKHLYTLDGGDIINALCF 241
Query: 1143 TADSQHVVTGSMDMSLKVWKLDG----GKLSQVLVGHS---DIVTCVAVSITNKTQVVSG 1195
+ +++ + + S+K+W L+G +L Q ++ S + C +++ + Q +
Sbjct: 242 -SPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 300
Query: 1196 SWDCNLI-VWDI 1206
+ NL+ VW +
Sbjct: 301 GYTDNLVRVWQV 312
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 3/125 (2%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSL 750
+GHS + + ++ + Q+ L+GS D ++ +WDL T + + H VL VA +
Sbjct: 60 RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119
Query: 751 VISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
++SG D + + + + T D H V+ V+ + + I ++ D V WN+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL 179
Query: 808 ENFTL 812
N L
Sbjct: 180 ANCKL 184
Score = 37.1 bits (82), Expect = 0.46
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-----V 1222
L L GH+ VT +A + ++S S D +I+W + + V
Sbjct: 7 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 66
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHV-PLLGFQITSDCARVV 1276
+ V ++ DG A+S + D TL +W+ G F H +L +SD ++V
Sbjct: 67 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
>BC000366-1|AAH00366.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 72.5 bits (170), Expect = 1e-11
Identities = 53/218 (24%), Positives = 101/218 (46%), Gaps = 14/218 (6%)
Query: 1045 TYKGHSSAIQTLLMMSD-GRRAMSSDRARNVHVWLV-----DSGIVLHSATGPSASI-DV 1097
T KGH+ + + +S+ R + + +W + + GI + G S + DV
Sbjct: 10 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 69
Query: 1098 TLNM--KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD 1155
++ ++A+ D ++R+W L G + RR V H + + A ++D++ +V+GS D
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTT---RRFVGHTKDVLSVAFSSDNRQIVSGSRD 126
Query: 1156 MSLKVWKLDGG-KLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXX 1213
++K+W G K + HS+ V+CV S + + VS WD + VW++
Sbjct: 127 KTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ V V+ DG++ S +D ++W+ G
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEG 224
Score = 66.1 bits (154), Expect = 9e-10
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 3/183 (1%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
++ GQ + G +LW + + + F GH+ +L + + +++ +++GS D ++
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 130
Query: 720 VWD-LHTLAVKTKILEHIAPVLCVAAIVNRS--LVISGGDDSAVIITSLVDGALVTKLDH 776
+W+ L + H V CV N S +++S G D V + +L + L T
Sbjct: 131 LWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG 190
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
H G + +V V DG++ +G +DG W++ L T+ G I+ + + +L
Sbjct: 191 HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCA 250
Query: 837 LQG 839
G
Sbjct: 251 ATG 253
Score = 65.7 bits (153), Expect = 1e-09
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 10/202 (4%)
Query: 975 SRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPN--NLLVLSGSEDRT 1031
S D + SG +++W L + H ++CV FSPN N +++S D+
Sbjct: 114 SSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL 173
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGP 1091
V VW LA+ + GH+ + T+ + DG S + +W ++ G L++ G
Sbjct: 174 VKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG 233
Query: 1092 SASIDVTLNM-KYAVLSDGDNSVRIWSLAGGDNSEDNRRSV----SHAERITCFAL--TA 1144
+ + +Y + + S++IW L G ++ ++ V S AE C +L +A
Sbjct: 234 DIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSA 293
Query: 1145 DSQHVVTGSMDMSLKVWKLDGG 1166
D Q + G D ++VW++ G
Sbjct: 294 DGQTLFAGYTDNLVRVWQVTIG 315
Score = 64.9 bits (151), Expect = 2e-09
Identities = 63/272 (23%), Positives = 114/272 (41%), Gaps = 19/272 (6%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T+QM R T N + Q + P L SRD + R + + Q
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-----ETNYGIPQ 56
Query: 1002 ATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSD 1061
L GH ++ V S + LSGS D T+ +W L + + + GH+ + ++ SD
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL------NMKYAVLSDG-DNSVR 1114
R+ +S R + + +W G+ ++ S S V+ + ++S G D V+
Sbjct: 117 NRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 1115 IWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVG 1174
+W+LA N + + H + ++ D +G D +W L+ GK L G
Sbjct: 176 VWNLA---NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232
Query: 1175 HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
DI+ + S N+ + + + ++ +WD+
Sbjct: 233 -GDIINALCFS-PNRYWLCAATGP-SIKIWDL 261
Score = 56.8 bits (131), Expect = 5e-07
Identities = 55/252 (21%), Positives = 113/252 (44%), Gaps = 19/252 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+S + +S DGQ SG G +R+W L+T GH + V FS +N ++SGS
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSR 125
Query: 1029 DRTVVVWQ-LADNSPSLTYKGHSSAIQTLLMM--SDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W L ++ + HS + + S +S + V VW + + +
Sbjct: 126 DKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLK 185
Query: 1086 HSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ G + ++ VT++ ++ + G D +W L N + ++ + I
Sbjct: 186 TNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDL----NEGKHLYTLDGGDIINALCF 241
Query: 1143 TADSQHVVTGSMDMSLKVWKLDG----GKLSQVLVGHS---DIVTCVAVSITNKTQVVSG 1195
+ +++ + + S+K+W L+G +L Q ++ S + C +++ + Q +
Sbjct: 242 -SPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 300
Query: 1196 SWDCNLI-VWDI 1206
+ NL+ VW +
Sbjct: 301 GYTDNLVRVWQV 312
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 3/125 (2%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSL 750
+GHS + + ++ + Q+ L+GS D ++ +WDL T + + H VL VA +
Sbjct: 60 RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119
Query: 751 VISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
++SG D + + + + T D H V+ V+ + + I ++ D V WN+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL 179
Query: 808 ENFTL 812
N L
Sbjct: 180 ANCKL 184
Score = 37.1 bits (82), Expect = 0.46
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-----V 1222
L L GH+ VT +A + ++S S D +I+W + + V
Sbjct: 7 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 66
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHV-PLLGFQITSDCARVV 1276
+ V ++ DG A+S + D TL +W+ G F H +L +SD ++V
Sbjct: 67 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
>BC000214-1|AAH00214.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 72.5 bits (170), Expect = 1e-11
Identities = 53/218 (24%), Positives = 101/218 (46%), Gaps = 14/218 (6%)
Query: 1045 TYKGHSSAIQTLLMMSD-GRRAMSSDRARNVHVWLV-----DSGIVLHSATGPSASI-DV 1097
T KGH+ + + +S+ R + + +W + + GI + G S + DV
Sbjct: 10 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 69
Query: 1098 TLNM--KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD 1155
++ ++A+ D ++R+W L G + RR V H + + A ++D++ +V+GS D
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTT---RRFVGHTKDVLSVAFSSDNRQIVSGSRD 126
Query: 1156 MSLKVWKLDGG-KLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXX 1213
++K+W G K + HS+ V+CV S + + VS WD + VW++
Sbjct: 127 KTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ V V+ DG++ S +D ++W+ G
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEG 224
Score = 66.1 bits (154), Expect = 9e-10
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 3/183 (1%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
++ GQ + G +LW + + + F GH+ +L + + +++ +++GS D ++
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 130
Query: 720 VWD-LHTLAVKTKILEHIAPVLCVAAIVNRS--LVISGGDDSAVIITSLVDGALVTKLDH 776
+W+ L + H V CV N S +++S G D V + +L + L T
Sbjct: 131 LWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG 190
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
H G + +V V DG++ +G +DG W++ L T+ G I+ + + +L
Sbjct: 191 HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCA 250
Query: 837 LQG 839
G
Sbjct: 251 ATG 253
Score = 65.7 bits (153), Expect = 1e-09
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 10/202 (4%)
Query: 975 SRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPN--NLLVLSGSEDRT 1031
S D + SG +++W L + H ++CV FSPN N +++S D+
Sbjct: 114 SSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL 173
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGP 1091
V VW LA+ + GH+ + T+ + DG S + +W ++ G L++ G
Sbjct: 174 VKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG 233
Query: 1092 SASIDVTLNM-KYAVLSDGDNSVRIWSLAGGDNSEDNRRSV----SHAERITCFAL--TA 1144
+ + +Y + + S++IW L G ++ ++ V S AE C +L +A
Sbjct: 234 DIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSA 293
Query: 1145 DSQHVVTGSMDMSLKVWKLDGG 1166
D Q + G D ++VW++ G
Sbjct: 294 DGQTLFAGYTDNLVRVWQVTIG 315
Score = 64.9 bits (151), Expect = 2e-09
Identities = 63/272 (23%), Positives = 114/272 (41%), Gaps = 19/272 (6%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T+QM R T N + Q + P L SRD + R + + Q
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-----ETNYGIPQ 56
Query: 1002 ATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSD 1061
L GH ++ V S + LSGS D T+ +W L + + + GH+ + ++ SD
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL------NMKYAVLSDG-DNSVR 1114
R+ +S R + + +W G+ ++ S S V+ + ++S G D V+
Sbjct: 117 NRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 1115 IWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVG 1174
+W+LA N + + H + ++ D +G D +W L+ GK L G
Sbjct: 176 VWNLA---NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232
Query: 1175 HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
DI+ + S N+ + + + ++ +WD+
Sbjct: 233 -GDIINALCFS-PNRYWLCAATGP-SIKIWDL 261
Score = 56.8 bits (131), Expect = 5e-07
Identities = 55/252 (21%), Positives = 113/252 (44%), Gaps = 19/252 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+S + +S DGQ SG G +R+W L+T GH + V FS +N ++SGS
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSR 125
Query: 1029 DRTVVVWQ-LADNSPSLTYKGHSSAIQTLLMM--SDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W L ++ + HS + + S +S + V VW + + +
Sbjct: 126 DKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLK 185
Query: 1086 HSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ G + ++ VT++ ++ + G D +W L N + ++ + I
Sbjct: 186 TNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDL----NEGKHLYTLDGGDIINALCF 241
Query: 1143 TADSQHVVTGSMDMSLKVWKLDG----GKLSQVLVGHS---DIVTCVAVSITNKTQVVSG 1195
+ +++ + + S+K+W L+G +L Q ++ S + C +++ + Q +
Sbjct: 242 -SPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 300
Query: 1196 SWDCNLI-VWDI 1206
+ NL+ VW +
Sbjct: 301 GYTDNLVRVWQV 312
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 3/125 (2%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSL 750
+GHS + + ++ + Q+ L+GS D ++ +WDL T + + H VL VA +
Sbjct: 60 RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119
Query: 751 VISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
++SG D + + + + T D H V+ V+ + + I ++ D V WN+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL 179
Query: 808 ENFTL 812
N L
Sbjct: 180 ANCKL 184
Score = 37.1 bits (82), Expect = 0.46
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-----V 1222
L L GH+ VT +A + ++S S D +I+W + + V
Sbjct: 7 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 66
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHV-PLLGFQITSDCARVV 1276
+ V ++ DG A+S + D TL +W+ G F H +L +SD ++V
Sbjct: 67 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
>AY159316-1|AAO21313.1| 347|Homo sapiens lung cancer oncogene 7
protein.
Length = 347
Score = 72.5 bits (170), Expect = 1e-11
Identities = 53/218 (24%), Positives = 101/218 (46%), Gaps = 14/218 (6%)
Query: 1045 TYKGHSSAIQTLLMMSD-GRRAMSSDRARNVHVWLV-----DSGIVLHSATGPSASI-DV 1097
T KGH+ + + +S+ R + + +W + + GI + G S + DV
Sbjct: 40 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 99
Query: 1098 TLNM--KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD 1155
++ ++A+ D ++R+W L G + RR V H + + A ++D++ +V+GS D
Sbjct: 100 VISSDGQFALSGSWDGTLRLWDLTTGTTT---RRFVGHTKDVLSVAFSSDNRQIVSGSRD 156
Query: 1156 MSLKVWKLDGG-KLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXX 1213
++K+W G K + HS+ V+CV S + + VS WD + VW++
Sbjct: 157 KTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 216
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ V V+ DG++ S +D ++W+ G
Sbjct: 217 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEG 254
Score = 66.1 bits (154), Expect = 9e-10
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 3/183 (1%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
++ GQ + G +LW + + + F GH+ +L + + +++ +++GS D ++
Sbjct: 101 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 160
Query: 720 VWD-LHTLAVKTKILEHIAPVLCVAAIVNRS--LVISGGDDSAVIITSLVDGALVTKLDH 776
+W+ L + H V CV N S +++S G D V + +L + L T
Sbjct: 161 LWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG 220
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
H G + +V V DG++ +G +DG W++ L T+ G I+ + + +L
Sbjct: 221 HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCA 280
Query: 837 LQG 839
G
Sbjct: 281 ATG 283
Score = 65.7 bits (153), Expect = 1e-09
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 10/202 (4%)
Query: 975 SRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPN--NLLVLSGSEDRT 1031
S D + SG +++W L + H ++CV FSPN N +++S D+
Sbjct: 144 SSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL 203
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGP 1091
V VW LA+ + GH+ + T+ + DG S + +W ++ G L++ G
Sbjct: 204 VKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG 263
Query: 1092 SASIDVTLNM-KYAVLSDGDNSVRIWSLAGGDNSEDNRRSV----SHAERITCFAL--TA 1144
+ + +Y + + S++IW L G ++ ++ V S AE C +L +A
Sbjct: 264 DIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSA 323
Query: 1145 DSQHVVTGSMDMSLKVWKLDGG 1166
D Q + G D ++VW++ G
Sbjct: 324 DGQTLFAGYTDNLVRVWQVTIG 345
Score = 64.9 bits (151), Expect = 2e-09
Identities = 63/272 (23%), Positives = 114/272 (41%), Gaps = 19/272 (6%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T+QM R T N + Q + P L SRD + R + + Q
Sbjct: 32 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-----ETNYGIPQ 86
Query: 1002 ATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSD 1061
L GH ++ V S + LSGS D T+ +W L + + + GH+ + ++ SD
Sbjct: 87 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 146
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL------NMKYAVLSDG-DNSVR 1114
R+ +S R + + +W G+ ++ S S V+ + ++S G D V+
Sbjct: 147 NRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 205
Query: 1115 IWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVG 1174
+W+LA N + + H + ++ D +G D +W L+ GK L G
Sbjct: 206 VWNLA---NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 262
Query: 1175 HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
DI+ + S N+ + + + ++ +WD+
Sbjct: 263 -GDIINALCFS-PNRYWLCAATGP-SIKIWDL 291
Score = 56.8 bits (131), Expect = 5e-07
Identities = 55/252 (21%), Positives = 113/252 (44%), Gaps = 19/252 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+S + +S DGQ SG G +R+W L+T GH + V FS +N ++SGS
Sbjct: 96 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSR 155
Query: 1029 DRTVVVWQ-LADNSPSLTYKGHSSAIQTLLMM--SDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W L ++ + HS + + S +S + V VW + + +
Sbjct: 156 DKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLK 215
Query: 1086 HSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ G + ++ VT++ ++ + G D +W L N + ++ + I
Sbjct: 216 TNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDL----NEGKHLYTLDGGDIINALCF 271
Query: 1143 TADSQHVVTGSMDMSLKVWKLDG----GKLSQVLVGHS---DIVTCVAVSITNKTQVVSG 1195
+ +++ + + S+K+W L+G +L Q ++ S + C +++ + Q +
Sbjct: 272 -SPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 330
Query: 1196 SWDCNLI-VWDI 1206
+ NL+ VW +
Sbjct: 331 GYTDNLVRVWQV 342
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 3/125 (2%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSL 750
+GHS + + ++ + Q+ L+GS D ++ +WDL T + + H VL VA +
Sbjct: 90 RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 149
Query: 751 VISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
++SG D + + + + T D H V+ V+ + + I ++ D V WN+
Sbjct: 150 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL 209
Query: 808 ENFTL 812
N L
Sbjct: 210 ANCKL 214
Score = 37.1 bits (82), Expect = 0.46
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-----V 1222
L L GH+ VT +A + ++S S D +I+W + + V
Sbjct: 37 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 96
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHV-PLLGFQITSDCARVV 1276
+ V ++ DG A+S + D TL +W+ G F H +L +SD ++V
Sbjct: 97 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 151
>AK222488-1|BAD96208.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 varia
protein.
Length = 317
Score = 72.1 bits (169), Expect = 1e-11
Identities = 53/218 (24%), Positives = 101/218 (46%), Gaps = 14/218 (6%)
Query: 1045 TYKGHSSAIQTLLMMSD-GRRAMSSDRARNVHVWLV-----DSGIVLHSATGPSASI-DV 1097
T KGH+ + + +S+ R + + +W + + GI + G S + DV
Sbjct: 10 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 69
Query: 1098 TLNM--KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD 1155
++ ++A+ D ++R+W L G + RR V H + + A ++D++ +V+GS D
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTT---RRFVGHTKDVLSVAFSSDNRQIVSGSRD 126
Query: 1156 MSLKVWKLDGG-KLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXX 1213
++K+W G K + HS+ V+CV S + + VS WD + VW++
Sbjct: 127 KTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
+ V V+ DG++ S +D ++W+ G
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDFNEG 224
Score = 65.3 bits (152), Expect = 2e-09
Identities = 43/183 (23%), Positives = 83/183 (45%), Gaps = 3/183 (1%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
++ GQ + G +LW + + + F GH+ +L + + +++ +++GS D ++
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 130
Query: 720 VWD-LHTLAVKTKILEHIAPVLCVAAIVNRS--LVISGGDDSAVIITSLVDGALVTKLDH 776
+W+ L + H V CV N S +++S G D V + +L + L T
Sbjct: 131 LWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG 190
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
H G + +V V DG++ +G +DG W+ L T+ G I+ + + +L
Sbjct: 191 HTGYLNTVTVSPDGSLCASGGKDGQAMLWDFNEGKHLYTLDGGDIINALCFSPNRYWLCA 250
Query: 837 LQG 839
G
Sbjct: 251 ATG 253
Score = 64.9 bits (151), Expect = 2e-09
Identities = 51/202 (25%), Positives = 91/202 (45%), Gaps = 10/202 (4%)
Query: 975 SRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPN--NLLVLSGSEDRT 1031
S D + SG +++W L + H ++CV FSPN N +++S D+
Sbjct: 114 SSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL 173
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGP 1091
V VW LA+ + GH+ + T+ + DG S + +W + G L++ G
Sbjct: 174 VKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDFNEGKHLYTLDGG 233
Query: 1092 SASIDVTLNM-KYAVLSDGDNSVRIWSLAGGDNSEDNRRSV----SHAERITCFAL--TA 1144
+ + +Y + + S++IW L G ++ ++ V S AE C +L +A
Sbjct: 234 DIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSA 293
Query: 1145 DSQHVVTGSMDMSLKVWKLDGG 1166
D Q + G D ++VW++ G
Sbjct: 294 DGQTLFAGYTDNLVRVWQVTIG 315
Score = 63.3 bits (147), Expect = 6e-09
Identities = 62/272 (22%), Positives = 113/272 (41%), Gaps = 19/272 (6%)
Query: 942 TKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ 1001
T+QM R T N + Q + P L SRD + R + + Q
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-----ETNYGIPQ 56
Query: 1002 ATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSD 1061
L GH ++ V S + LSGS D T+ +W L + + + GH+ + ++ SD
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 1062 GRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL------NMKYAVLSDG-DNSVR 1114
R+ +S R + + +W G+ ++ S S V+ + ++S G D V+
Sbjct: 117 NRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 1115 IWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVG 1174
+W+LA N + + H + ++ D +G D +W + GK L G
Sbjct: 176 VWNLA---NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDFNEGKHLYTLDG 232
Query: 1175 HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
DI+ + S N+ + + + ++ +WD+
Sbjct: 233 -GDIINALCFS-PNRYWLCAATGP-SIKIWDL 261
Score = 55.2 bits (127), Expect = 2e-06
Identities = 54/252 (21%), Positives = 112/252 (44%), Gaps = 19/252 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+S + +S DGQ SG G +R+W L+T GH + V FS +N ++SGS
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSR 125
Query: 1029 DRTVVVWQ-LADNSPSLTYKGHSSAIQTLLMM--SDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W L ++ + HS + + S +S + V VW + + +
Sbjct: 126 DKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLK 185
Query: 1086 HSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFAL 1142
+ G + ++ VT++ ++ + G D +W N + ++ + I
Sbjct: 186 TNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDF----NEGKHLYTLDGGDIINALCF 241
Query: 1143 TADSQHVVTGSMDMSLKVWKLDG----GKLSQVLVGHS---DIVTCVAVSITNKTQVVSG 1195
+ +++ + + S+K+W L+G +L Q ++ S + C +++ + Q +
Sbjct: 242 -SPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 300
Query: 1196 SWDCNLI-VWDI 1206
+ NL+ VW +
Sbjct: 301 GYTDNLVRVWQV 312
Score = 49.6 bits (113), Expect = 8e-05
Identities = 40/171 (23%), Positives = 75/171 (43%), Gaps = 4/171 (2%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSL 750
+GHS + + ++ + Q+ L+GS D ++ +WDL T + + H VL VA +
Sbjct: 60 RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119
Query: 751 VISGGDDSAVIITSLVDGALVTKLDH-HRGSVTSVKVIQDGN--IFITGSQDGTVCTWNV 807
++SG D + + + + T D H V+ V+ + + I ++ D V WN+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL 179
Query: 808 ENFTLLSTVTAGVP-IHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPL 857
N L + ++ V+ D + D + L F G +L+ L
Sbjct: 180 ANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDFNEGKHLYTL 230
Score = 37.1 bits (82), Expect = 0.46
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Query: 1168 LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXK-----V 1222
L L GH+ VT +A + ++S S D +I+W + + V
Sbjct: 7 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 66
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHV-PLLGFQITSDCARVV 1276
+ V ++ DG A+S + D TL +W+ G F H +L +SD ++V
Sbjct: 67 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
>BC107125-1|AAI07126.1| 248|Homo sapiens WDR86 protein protein.
Length = 248
Score = 71.3 bits (167), Expect = 2e-11
Identities = 51/211 (24%), Positives = 85/211 (40%), Gaps = 8/211 (3%)
Query: 956 ITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVT 1015
+TL + DL C E + G L +G G +VWQ+++ TL GH G + C+
Sbjct: 13 LTLAYSAPWDLPSTPCAEEAAAGGLLVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLV 72
Query: 1016 FSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVH 1075
+GS D T+ W + ++ H ++ L +++ R S R V
Sbjct: 73 LDTPGHTAFTGSTDATIRAWDILSGEQLRVFREHRGSVICLELVN--RLVYSGSADRTVK 130
Query: 1076 VWLVDSGIVLHSATGPSASID-VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHA 1134
WL D+G + + T ++ + + GD R + G E R H
Sbjct: 131 CWLADTGECVRTFTAHRRNVSALKYHAGTLFTGSGDACARAFDAQSG---ELRRVFRGHT 187
Query: 1135 ERITCFALTADSQHVVTGSMDMSLKVWKLDG 1165
I C + Q + T S D +L++W + G
Sbjct: 188 FIINC--IQVHGQVLYTASHDGALRLWDVRG 216
Score = 68.1 bits (159), Expect = 2e-10
Identities = 51/187 (27%), Positives = 88/187 (47%), Gaps = 11/187 (5%)
Query: 1022 LVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDS 1081
L+++GS D T VWQ+A T +GH+ A+ L++ + G A + + W + S
Sbjct: 37 LLVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLVLDTPGHTAFTGSTDATIRAWDILS 96
Query: 1082 GIVLHSATGPSASIDVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITC 1139
G L S+ + L + ++ G D +V+ W LA D E R +H ++
Sbjct: 97 GEQLRVFREHRGSV-ICLELVNRLVYSGSADRTVKCW-LA--DTGECVRTFTAHRRNVS- 151
Query: 1140 FALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDC 1199
AL + + TGS D + + G+L +V GH+ I+ C+ V + + + S D
Sbjct: 152 -ALKYHAGTLFTGSGDACARAFDAQSGELRRVFRGHTFIINCIQV---HGQVLYTASHDG 207
Query: 1200 NLIVWDI 1206
L +WD+
Sbjct: 208 ALRLWDV 214
Score = 67.3 bits (157), Expect = 4e-10
Identities = 44/149 (29%), Positives = 71/149 (47%), Gaps = 4/149 (2%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
A +G LV + G ++W + S T +GH+G++LC+ + TGS D ++
Sbjct: 32 AAAGGLLVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLVLDTPGHTAFTGSTDATIRA 91
Query: 721 WDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
WD+ + EH V+C+ +VNR LV SG D V G V HR +
Sbjct: 92 WDILSGEQLRVFREHRGSVICL-ELVNR-LVYSGSADRTVKCWLADTGECVRTFTAHRRN 149
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
V+++K G +F TGS D ++ ++
Sbjct: 150 VSALK-YHAGTLF-TGSGDACARAFDAQS 176
Score = 54.0 bits (124), Expect = 4e-06
Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 3/112 (2%)
Query: 1149 VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINT 1208
+VTGS D + KVW++ G Q L GH+ V C+ + T +GS D + WDI +
Sbjct: 38 LVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLVLDTPGHT-AFTGSTDATIRAWDILS 96
Query: 1209 XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH 1260
V C+++ + S + D+T+ W G + +F+ H
Sbjct: 97 GEQLRVFREHRGSVICLELV--NRLVYSGSADRTVKCWLADTGECVRTFTAH 146
Score = 42.3 bits (95), Expect = 0.012
Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 6/122 (4%)
Query: 1105 VLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLD 1164
V D + ++W +A G + R H + C L TGS D +++ W +
Sbjct: 39 VTGSTDGTAKVWQVASGCCHQTLR---GHTGAVLCLVLDTPGHTAFTGSTDATIRAWDIL 95
Query: 1165 GGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTC 1224
G+ +V H V C + + N+ V SGS D + W +T V+
Sbjct: 96 SGEQLRVFREHRGSVIC--LELVNRL-VYSGSADRTVKCWLADTGECVRTFTAHRRNVSA 152
Query: 1225 VK 1226
+K
Sbjct: 153 LK 154
Score = 42.3 bits (95), Expect = 0.012
Identities = 30/129 (23%), Positives = 51/129 (39%), Gaps = 6/129 (4%)
Query: 679 WHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAP 738
W I+S ++ F+ H GS++C+ + Y +GS D +V W T H
Sbjct: 92 WDILSGEQLRVFREHRGSVICLELVNRLVY--SGSADRTVKCWLADTGECVRTFTAHRRN 149
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQ 798
V + + + +G D+ G L H + ++V G + T S
Sbjct: 150 VSALK--YHAGTLFTGSGDACARAFDAQSGELRRVFRGHTFIINCIQV--HGQVLYTASH 205
Query: 799 DGTVCTWNV 807
DG + W+V
Sbjct: 206 DGALRLWDV 214
Score = 34.7 bits (76), Expect = 2.5
Identities = 16/67 (23%), Positives = 28/67 (41%)
Query: 741 CVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDG 800
C L+++G D + + G L H G+V + + G+ TGS D
Sbjct: 28 CAEEAAAGGLLVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLVLDTPGHTAFTGSTDA 87
Query: 801 TVCTWNV 807
T+ W++
Sbjct: 88 TIRAWDI 94
>AL121993-4|CAI22739.1| 943|Homo sapiens WD repeat domain 3 protein.
Length = 943
Score = 70.5 bits (165), Expect = 4e-11
Identities = 47/177 (26%), Positives = 79/177 (44%), Gaps = 6/177 (3%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
V +W L L G +TC+ SP+ L + G ED ++ ++ L ++T+ GH
Sbjct: 47 VFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGH 106
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMK---YAVL 1106
+AI TL G R S + ++ VW V + L+ G +I L ++ V
Sbjct: 107 KAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVT 166
Query: 1107 SDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKL 1163
S D V+ W L D + V H + L ++ + ++TG+ D L+VW +
Sbjct: 167 SGKDTMVKWWDL---DTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSELRVWDI 220
Score = 64.9 bits (151), Expect = 2e-09
Identities = 72/318 (22%), Positives = 127/318 (39%), Gaps = 29/318 (9%)
Query: 949 QTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHI 1008
Q T+ IT+ +SD + L S D + A +++W ST LQ
Sbjct: 402 QPVRTSRITI-GGHRSD---VRTLSFSSDN-IAVLSAAADSIKIWNRST--LQCIRTMTC 454
Query: 1009 GHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSS 1068
+ C F P + V+ G++ + ++ LA + T H A+ ++ + D R ++
Sbjct: 455 EYALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTG 514
Query: 1069 DRARNVHVWLVDSGIVL-HSATGPSASIDVTL---------------NMKYAVLSDGDNS 1112
++V W D +V ++T S+ T N K +S D +
Sbjct: 515 GADKSVKFW--DFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCT 572
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
V+I+ + D + H + C ++ D + TGS D ++K+W LD G + L
Sbjct: 573 VKIFYV---DTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSL 629
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGT 1232
H D V + + +G D + WD + ++ C+ V+ G
Sbjct: 630 FAHDDSVMYLQFVPKSHLFFTAGK-DHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGD 688
Query: 1233 IAVSCAEDKTLIIWETKR 1250
VS + DK+L +WE R
Sbjct: 689 YVVSSSHDKSLRLWERTR 706
Score = 63.7 bits (148), Expect = 5e-09
Identities = 41/161 (25%), Positives = 70/161 (43%), Gaps = 3/161 (1%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
++CL S DG A G G +R++ L + T NGH IT + + + SGS+
Sbjct: 68 VTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSK 127
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D ++VW + + S KGH AI L + + ++S + V W +D+ +
Sbjct: 128 DTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTM 187
Query: 1089 TGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSED 1126
G + + K + D+ +R+W +A ED
Sbjct: 188 VGHRTEVWGLVLLSEEKRLITGASDSELRVWDIAYLQEIED 228
Score = 60.1 bits (139), Expect = 6e-08
Identities = 34/147 (23%), Positives = 68/147 (46%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+P G HL + G +++ ++S TF GH +I + + L +GS+DT +IV
Sbjct: 74 SPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIV 133
Query: 721 WDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
WD+ + ++ H + + ++L+++ G D+ V L + HR
Sbjct: 134 WDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTE 193
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWNV 807
V + ++ + ITG+ D + W++
Sbjct: 194 VWGLVLLSEEKRLITGASDSELRVWDI 220
Score = 56.4 bits (130), Expect = 7e-07
Identities = 54/235 (22%), Positives = 105/235 (44%), Gaps = 21/235 (8%)
Query: 669 LAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL-A 727
L PS PQ + S++ T GH + + + ++ +L+ + D S+ +W+ TL
Sbjct: 394 LNPSLPTPQP---VRTSRI-TIGGHRSDVRTLSFSSDNIAVLSAAAD-SIKIWNRSTLQC 448
Query: 728 VKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVI 787
++T E+ LC + V+ G + + L G L+ +D H G++ S+ +
Sbjct: 449 IRTMTCEY---ALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLS 505
Query: 788 QDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDV--TDDNVFLLTLQGDNELHL 845
D F+TG D +V W+ E ++ + + D++V ++ + +L
Sbjct: 506 PDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLA 565
Query: 846 RTFITGT----YLHPLK------RHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ + T Y+ LK HK V C ++HD + +A G AD+ + ++ L
Sbjct: 566 VSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGL 620
Score = 56.0 bits (129), Expect = 9e-07
Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 11/158 (6%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVW 721
P + +V+ G QL+ + S + + T H G++ M ++ + + +TG D SV W
Sbjct: 464 PGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFW 523
Query: 722 DLH----------TLAVK-TKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGAL 770
D L+VK T+ L+ VLCV+ N+ L+ D V I +
Sbjct: 524 DFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKF 583
Query: 771 VTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
L H+ V + + DG + TGS D V W ++
Sbjct: 584 FLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLD 621
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/141 (19%), Positives = 65/141 (46%)
Query: 668 VLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLA 727
V P+ +W + K+ +G + C+C + + +L G ED S+ ++ L +
Sbjct: 39 VAVPACEHVFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGE 98
Query: 728 VKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVI 787
H A + + + SG D+ +I+ +++ + + +L H+ ++T +
Sbjct: 99 GNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFL 158
Query: 788 QDGNIFITGSQDGTVCTWNVE 808
++ N+ +T +D V W+++
Sbjct: 159 REKNLLVTSGKDTMVKWWDLD 179
Score = 51.2 bits (117), Expect = 3e-05
Identities = 51/245 (20%), Positives = 94/245 (38%), Gaps = 13/245 (5%)
Query: 875 RVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTED 934
+V +G ++ LY L S LL T GG ++ + E
Sbjct: 468 QVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFEL 527
Query: 935 NLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQ 994
K++ +QT++ LQ ++ L C+ S + +L A V+++
Sbjct: 528 VKDENSTQKRLSVKQTRT------LQLDEDVL----CVSYSPNQKLLAVSLLDCTVKIFY 577
Query: 995 LSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQ 1054
+ T + +L GH + C+ S + L+ +GS DR V +W L + H ++
Sbjct: 578 VDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVM 637
Query: 1055 TLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI---DVTLNMKYAVLSDGDN 1111
L + ++ + + W D + + G I V+ + Y V S D
Sbjct: 638 YLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDK 697
Query: 1112 SVRIW 1116
S+R+W
Sbjct: 698 SLRLW 702
Score = 47.2 bits (107), Expect = 4e-04
Identities = 28/120 (23%), Positives = 54/120 (45%)
Query: 697 ILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGD 756
+LC+ + + L D +V ++ + TL + H PV+C+ + +L+ +G
Sbjct: 552 VLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSA 611
Query: 757 DSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV 816
D V I L G L H SV ++ + ++F T +D + W+ + F + T+
Sbjct: 612 DRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTL 671
Score = 46.0 bits (104), Expect = 0.001
Identities = 41/178 (23%), Positives = 72/178 (40%), Gaps = 7/178 (3%)
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGP 1091
V +W L L +G + L DG ++ ++ + SG + G
Sbjct: 47 VFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGH 106
Query: 1092 SASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQH 1148
A+I + + L+ G D + +W + N R H + IT +
Sbjct: 107 KAAITTLKYDQLGGRLASGSKDTDIIVWDVI---NESGLYRLKGHKDAITQALFLREKNL 163
Query: 1149 VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+VT D +K W LD + +VGH V + V ++ + ++++G+ D L VWDI
Sbjct: 164 LVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGL-VLLSEEKRLITGASDSELRVWDI 220
Score = 43.2 bits (97), Expect = 0.007
Identities = 25/112 (22%), Positives = 49/112 (43%), Gaps = 2/112 (1%)
Query: 1135 ERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVS 1194
+ +TC + D H+ G D S++++ L G+ + GH +T + ++ S
Sbjct: 66 QEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLG-GRLAS 124
Query: 1195 GSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
GS D ++IVWD+ +T + + V+ +D T++ W
Sbjct: 125 GSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKD-TMVKW 175
Score = 41.9 bits (94), Expect = 0.016
Identities = 23/114 (20%), Positives = 46/114 (40%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH ++CM ++ + + TGS D +V +W L + H V+ + + L
Sbjct: 589 GHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLF 648
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
+ G D + + L+ H + + V G+ ++ S D ++ W
Sbjct: 649 FTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLW 702
Score = 41.5 bits (93), Expect = 0.021
Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
Query: 718 VIVWDLHTLAVKTKILEHIAP-VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
V +WDL K IL+ + V C+ + + G +D ++ I SL+ G +
Sbjct: 47 VFIWDLRK-GEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNG 105
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
H+ ++T++K Q G +GS+D + W+V N
Sbjct: 106 HKAAITTLKYDQLGGRLASGSKDTDIIVWDVIN 138
Score = 35.1 bits (77), Expect = 1.9
Identities = 16/65 (24%), Positives = 27/65 (41%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
LQ P A + W + T +GH I C+ V+ Y+++ S D S
Sbjct: 639 LQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKS 698
Query: 718 VIVWD 722
+ +W+
Sbjct: 699 LRLWE 703
>AF083217-1|AAD45865.1| 943|Homo sapiens WD repeat protein WDR3
protein.
Length = 943
Score = 70.5 bits (165), Expect = 4e-11
Identities = 47/177 (26%), Positives = 79/177 (44%), Gaps = 6/177 (3%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
V +W L L G +TC+ SP+ L + G ED ++ ++ L ++T+ GH
Sbjct: 47 VFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGH 106
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMK---YAVL 1106
+AI TL G R S + ++ VW V + L+ G +I L ++ V
Sbjct: 107 KAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVT 166
Query: 1107 SDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKL 1163
S D V+ W L D + V H + L ++ + ++TG+ D L+VW +
Sbjct: 167 SGKDTMVKWWDL---DTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSELRVWDI 220
Score = 64.9 bits (151), Expect = 2e-09
Identities = 72/318 (22%), Positives = 127/318 (39%), Gaps = 29/318 (9%)
Query: 949 QTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHI 1008
Q T+ IT+ +SD + L S D + A +++W ST LQ
Sbjct: 402 QPVRTSRITI-GGHRSD---VRTLSFSSDN-IAVLSAAADSIKIWNRST--LQCIRTMTC 454
Query: 1009 GHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSS 1068
+ C F P + V+ G++ + ++ LA + T H A+ ++ + D R ++
Sbjct: 455 EYALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTG 514
Query: 1069 DRARNVHVWLVDSGIVL-HSATGPSASIDVTL---------------NMKYAVLSDGDNS 1112
++V W D +V ++T S+ T N K +S D +
Sbjct: 515 GADKSVKFW--DFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCT 572
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
V+I+ + D + H + C ++ D + TGS D ++K+W LD G + L
Sbjct: 573 VKIFYV---DTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSL 629
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGT 1232
H D V + + +G D + WD + ++ C+ V+ G
Sbjct: 630 FAHDDSVMYLQFVPKSHLFFTAGK-DHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGD 688
Query: 1233 IAVSCAEDKTLIIWETKR 1250
VS + DK+L +WE R
Sbjct: 689 YVVSSSHDKSLRLWERTR 706
Score = 63.7 bits (148), Expect = 5e-09
Identities = 41/161 (25%), Positives = 70/161 (43%), Gaps = 3/161 (1%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
++CL S DG A G G +R++ L + T NGH IT + + + SGS+
Sbjct: 68 VTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSK 127
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D ++VW + + S KGH AI L + + ++S + V W +D+ +
Sbjct: 128 DTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTM 187
Query: 1089 TGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSED 1126
G + + K + D+ +R+W +A ED
Sbjct: 188 VGHRTEVWGLVLLSEEKRLITGASDSELRVWDIAYLQEIED 228
Score = 60.1 bits (139), Expect = 6e-08
Identities = 34/147 (23%), Positives = 68/147 (46%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+P G HL + G +++ ++S TF GH +I + + L +GS+DT +IV
Sbjct: 74 SPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIV 133
Query: 721 WDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
WD+ + ++ H + + ++L+++ G D+ V L + HR
Sbjct: 134 WDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTE 193
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWNV 807
V + ++ + ITG+ D + W++
Sbjct: 194 VWGLVLLSEEKRLITGASDSELRVWDI 220
Score = 56.4 bits (130), Expect = 7e-07
Identities = 54/235 (22%), Positives = 105/235 (44%), Gaps = 21/235 (8%)
Query: 669 LAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL-A 727
L PS PQ + S++ T GH + + + ++ +L+ + D S+ +W+ TL
Sbjct: 394 LNPSLPTPQP---VRTSRI-TIGGHRSDVRTLSFSSDNIAVLSAAAD-SIKIWNRSTLQC 448
Query: 728 VKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVI 787
++T E+ LC + V+ G + + L G L+ +D H G++ S+ +
Sbjct: 449 IRTMTCEY---ALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLS 505
Query: 788 QDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDV--TDDNVFLLTLQGDNELHL 845
D F+TG D +V W+ E ++ + + D++V ++ + +L
Sbjct: 506 PDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLA 565
Query: 846 RTFITGT----YLHPLK------RHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ + T Y+ LK HK V C ++HD + +A G AD+ + ++ L
Sbjct: 566 VSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGL 620
Score = 56.0 bits (129), Expect = 9e-07
Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 11/158 (6%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVW 721
P + +V+ G QL+ + S + + T H G++ M ++ + + +TG D SV W
Sbjct: 464 PGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFW 523
Query: 722 DLH----------TLAVK-TKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGAL 770
D L+VK T+ L+ VLCV+ N+ L+ D V I +
Sbjct: 524 DFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKF 583
Query: 771 VTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
L H+ V + + DG + TGS D V W ++
Sbjct: 584 FLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLD 621
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/141 (19%), Positives = 65/141 (46%)
Query: 668 VLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLA 727
V P+ +W + K+ +G + C+C + + +L G ED S+ ++ L +
Sbjct: 39 VAVPACEHVFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGE 98
Query: 728 VKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVI 787
H A + + + SG D+ +I+ +++ + + +L H+ ++T +
Sbjct: 99 GNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFL 158
Query: 788 QDGNIFITGSQDGTVCTWNVE 808
++ N+ +T +D V W+++
Sbjct: 159 REKNLLVTSGKDTMVKWWDLD 179
Score = 51.2 bits (117), Expect = 3e-05
Identities = 51/245 (20%), Positives = 94/245 (38%), Gaps = 13/245 (5%)
Query: 875 RVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTED 934
+V +G ++ LY L S LL T GG ++ + E
Sbjct: 468 QVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFEL 527
Query: 935 NLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQ 994
K++ +QT++ LQ ++ L C+ S + +L A V+++
Sbjct: 528 VKDENSTQKRLSVKQTRT------LQLDEDVL----CVSYSPNQKLLAVSLLDCTVKIFY 577
Query: 995 LSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQ 1054
+ T + +L GH + C+ S + L+ +GS DR V +W L + H ++
Sbjct: 578 VDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVM 637
Query: 1055 TLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI---DVTLNMKYAVLSDGDN 1111
L + ++ + + W D + + G I V+ + Y V S D
Sbjct: 638 YLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDK 697
Query: 1112 SVRIW 1116
S+R+W
Sbjct: 698 SLRLW 702
Score = 47.2 bits (107), Expect = 4e-04
Identities = 28/120 (23%), Positives = 54/120 (45%)
Query: 697 ILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGD 756
+LC+ + + L D +V ++ + TL + H PV+C+ + +L+ +G
Sbjct: 552 VLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSA 611
Query: 757 DSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV 816
D V I L G L H SV ++ + ++F T +D + W+ + F + T+
Sbjct: 612 DRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTL 671
Score = 46.0 bits (104), Expect = 0.001
Identities = 41/178 (23%), Positives = 72/178 (40%), Gaps = 7/178 (3%)
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGP 1091
V +W L L +G + L DG ++ ++ + SG + G
Sbjct: 47 VFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGH 106
Query: 1092 SASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQH 1148
A+I + + L+ G D + +W + N R H + IT +
Sbjct: 107 KAAITTLKYDQLGGRLASGSKDTDIIVWDVI---NESGLYRLKGHKDAITQALFLREKNL 163
Query: 1149 VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+VT D +K W LD + +VGH V + V ++ + ++++G+ D L VWDI
Sbjct: 164 LVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGL-VLLSEEKRLITGASDSELRVWDI 220
Score = 43.2 bits (97), Expect = 0.007
Identities = 25/112 (22%), Positives = 49/112 (43%), Gaps = 2/112 (1%)
Query: 1135 ERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVS 1194
+ +TC + D H+ G D S++++ L G+ + GH +T + ++ S
Sbjct: 66 QEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLG-GRLAS 124
Query: 1195 GSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
GS D ++IVWD+ +T + + V+ +D T++ W
Sbjct: 125 GSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKD-TMVKW 175
Score = 41.9 bits (94), Expect = 0.016
Identities = 23/114 (20%), Positives = 46/114 (40%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH ++CM ++ + + TGS D +V +W L + H V+ + + L
Sbjct: 589 GHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLF 648
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
+ G D + + L+ H + + V G+ ++ S D ++ W
Sbjct: 649 FTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLW 702
Score = 41.5 bits (93), Expect = 0.021
Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
Query: 718 VIVWDLHTLAVKTKILEHIAP-VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
V +WDL K IL+ + V C+ + + G +D ++ I SL+ G +
Sbjct: 47 VFIWDLRK-GEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNG 105
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVEN 809
H+ ++T++K Q G +GS+D + W+V N
Sbjct: 106 HKAAITTLKYDQLGGRLASGSKDTDIIVWDVIN 138
Score = 35.1 bits (77), Expect = 1.9
Identities = 16/65 (24%), Positives = 27/65 (41%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
LQ P A + W + T +GH I C+ V+ Y+++ S D S
Sbjct: 639 LQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKS 698
Query: 718 VIVWD 722
+ +W+
Sbjct: 699 LRLWE 703
>BC023662-1|AAH23662.2| 475|Homo sapiens RRP9, small subunit (SSU)
processome component, homolog (yeast) protein.
Length = 475
Score = 70.1 bits (164), Expect = 5e-11
Identities = 44/153 (28%), Positives = 73/153 (47%), Gaps = 3/153 (1%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ C+ +S DG+ ASG L+ +W+ + + T GH ++ + F + S S
Sbjct: 202 VLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSH 261
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLV--DSGIVLH 1086
DR+V VW +A+NS T GH A+ L +S + R V VW + +S +V +
Sbjct: 262 DRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFY 321
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLA 1119
G I + +N ++ V D SV +W L+
Sbjct: 322 GHQGSIDCIHL-INEEHMVSGADDGSVALWGLS 353
Score = 67.7 bits (158), Expect = 3e-10
Identities = 49/218 (22%), Positives = 96/218 (44%), Gaps = 20/218 (9%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL-----------ADNSPSLTYKGHSSA 1052
L GH ITC+ +P++ + S ++D +++ W + A GHSS
Sbjct: 142 LRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKPPGHSSH 201
Query: 1053 IQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID---VTLNMKYAVLSDG 1109
+ + + SDG+ S DR++ + +W S L++ TG ++ +
Sbjct: 202 VLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSH 261
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLS 1169
D SV++W++A E H + + + V G D +++VWK+ +
Sbjct: 262 DRSVKVWNVAENSYVE---TLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIP-EESQ 317
Query: 1170 QVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDIN 1207
V GH + C + + N+ +VSG+ D ++ +W ++
Sbjct: 318 LVFYGHQGSIDC--IHLINEEHMVSGADDGSVALWGLS 353
Score = 57.6 bits (133), Expect = 3e-07
Identities = 33/150 (22%), Positives = 71/150 (47%), Gaps = 2/150 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ ++ G++L + +W S ++TF GH ++ + R + L + S D S
Sbjct: 205 MAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSHDRS 264
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V VW++ + + H V + A+ V +GG D V + + + + + H
Sbjct: 265 VKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLV-FYGH 323
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
+GS+ + +I + ++ ++G+ DG+V W +
Sbjct: 324 QGSIDCIHLINEEHM-VSGADDGSVALWGL 352
Score = 52.0 bits (119), Expect = 2e-05
Identities = 26/116 (22%), Positives = 52/116 (44%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GHS +LCM ++ + +YL +G +++W+ + H V +A +
Sbjct: 197 GHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQL 256
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
S D +V + ++ + + V L H+ +V ++ + G +DGTV W +
Sbjct: 257 YSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKI 312
Score = 46.0 bits (104), Expect = 0.001
Identities = 33/145 (22%), Positives = 63/145 (43%), Gaps = 11/145 (7%)
Query: 683 SNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWD------LHTLAVKTKILE-- 734
+++ + +GH SI C+ VT + + + ++D S+I W LH + K E
Sbjct: 135 ASADIRVLRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGK 194
Query: 735 ---HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN 791
H + VLC+A + + SG ++I + HR +V+ + + +
Sbjct: 195 PPGHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTH 254
Query: 792 IFITGSQDGTVCTWNVENFTLLSTV 816
+ S D +V WNV + + T+
Sbjct: 255 QLYSTSHDRSVKVWNVAENSYVETL 279
Score = 39.5 bits (88), Expect = 0.087
Identities = 21/115 (18%), Positives = 46/115 (40%), Gaps = 1/115 (0%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H+ + C A+++D +++ +G + +W+ + GH D V+ +A Q+
Sbjct: 198 HSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFR-RGTHQL 256
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
S S D ++ VW++ V + + D T+ +W+
Sbjct: 257 YSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWK 311
Score = 38.3 bits (85), Expect = 0.20
Identities = 29/134 (21%), Positives = 53/134 (39%), Gaps = 12/134 (8%)
Query: 1124 SEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL----------- 1172
S D R H ITC +T D + + + D S+ W ++ G+ V+
Sbjct: 136 SADIRVLRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKP 195
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGT 1232
GHS V C+A+S K + SG +++W+ + V+ +
Sbjct: 196 PGHSSHVLCMAISSDGK-YLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTH 254
Query: 1233 IAVSCAEDKTLIIW 1246
S + D+++ +W
Sbjct: 255 QLYSTSHDRSVKVW 268
Score = 36.7 bits (81), Expect = 0.61
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 983 SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
+G G VRVW++ Q GH G I C+ N ++SG++D +V +W L+ P
Sbjct: 300 AGGRDGTVRVWKIPEES-QLVFYGHQGSIDCIHLI-NEEHMVSGADDGSVALWGLSKKRP 357
>BC010048-1|AAH10048.1| 475|Homo sapiens RRP9, small subunit (SSU)
processome component, homolog (yeast) protein.
Length = 475
Score = 70.1 bits (164), Expect = 5e-11
Identities = 44/153 (28%), Positives = 73/153 (47%), Gaps = 3/153 (1%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ C+ +S DG+ ASG L+ +W+ + + T GH ++ + F + S S
Sbjct: 202 VLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSH 261
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLV--DSGIVLH 1086
DR+V VW +A+NS T GH A+ L +S + R V VW + +S +V +
Sbjct: 262 DRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFY 321
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLA 1119
G I + +N ++ V D SV +W L+
Sbjct: 322 GHQGSIDCIHL-INEEHMVSGADDGSVALWGLS 353
Score = 67.7 bits (158), Expect = 3e-10
Identities = 49/218 (22%), Positives = 96/218 (44%), Gaps = 20/218 (9%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL-----------ADNSPSLTYKGHSSA 1052
L GH ITC+ +P++ + S ++D +++ W + A GHSS
Sbjct: 142 LRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKPPGHSSH 201
Query: 1053 IQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID---VTLNMKYAVLSDG 1109
+ + + SDG+ S DR++ + +W S L++ TG ++ +
Sbjct: 202 VLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSH 261
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLS 1169
D SV++W++A E H + + + V G D +++VWK+ +
Sbjct: 262 DRSVKVWNVAENSYVE---TLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIP-EESQ 317
Query: 1170 QVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDIN 1207
V GH + C + + N+ +VSG+ D ++ +W ++
Sbjct: 318 LVFYGHQGSIDC--IHLINEEHMVSGADDGSVALWGLS 353
Score = 57.6 bits (133), Expect = 3e-07
Identities = 33/150 (22%), Positives = 71/150 (47%), Gaps = 2/150 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ ++ G++L + +W S ++TF GH ++ + R + L + S D S
Sbjct: 205 MAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSHDRS 264
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V VW++ + + H V + A+ V +GG D V + + + + + H
Sbjct: 265 VKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLV-FYGH 323
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
+GS+ + +I + ++ ++G+ DG+V W +
Sbjct: 324 QGSIDCIHLINEEHM-VSGADDGSVALWGL 352
Score = 52.0 bits (119), Expect = 2e-05
Identities = 26/116 (22%), Positives = 52/116 (44%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GHS +LCM ++ + +YL +G +++W+ + H V +A +
Sbjct: 197 GHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQL 256
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
S D +V + ++ + + V L H+ +V ++ + G +DGTV W +
Sbjct: 257 YSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKI 312
Score = 46.0 bits (104), Expect = 0.001
Identities = 33/145 (22%), Positives = 63/145 (43%), Gaps = 11/145 (7%)
Query: 683 SNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWD------LHTLAVKTKILE-- 734
+++ + +GH SI C+ VT + + + ++D S+I W LH + K E
Sbjct: 135 ASADIRVLRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGK 194
Query: 735 ---HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN 791
H + VLC+A + + SG ++I + HR +V+ + + +
Sbjct: 195 PPGHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTH 254
Query: 792 IFITGSQDGTVCTWNVENFTLLSTV 816
+ S D +V WNV + + T+
Sbjct: 255 QLYSTSHDRSVKVWNVAENSYVETL 279
Score = 39.5 bits (88), Expect = 0.087
Identities = 21/115 (18%), Positives = 46/115 (40%), Gaps = 1/115 (0%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H+ + C A+++D +++ +G + +W+ + GH D V+ +A Q+
Sbjct: 198 HSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFR-RGTHQL 256
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
S S D ++ VW++ V + + D T+ +W+
Sbjct: 257 YSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWK 311
Score = 38.3 bits (85), Expect = 0.20
Identities = 29/134 (21%), Positives = 53/134 (39%), Gaps = 12/134 (8%)
Query: 1124 SEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL----------- 1172
S D R H ITC +T D + + + D S+ W ++ G+ V+
Sbjct: 136 SADIRVLRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKP 195
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGT 1232
GHS V C+A+S K + SG +++W+ + V+ +
Sbjct: 196 PGHSSHVLCMAISSDGK-YLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTH 254
Query: 1233 IAVSCAEDKTLIIW 1246
S + D+++ +W
Sbjct: 255 QLYSTSHDRSVKVW 268
Score = 36.7 bits (81), Expect = 0.61
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 983 SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
+G G VRVW++ Q GH G I C+ N ++SG++D +V +W L+ P
Sbjct: 300 AGGRDGTVRVWKIPEES-QLVFYGHQGSIDCIHLI-NEEHMVSGADDGSVALWGLSKKRP 357
>BC009879-1|AAH09879.1| 475|Homo sapiens RRP9, small subunit (SSU)
processome component, homolog (yeast) protein.
Length = 475
Score = 70.1 bits (164), Expect = 5e-11
Identities = 44/153 (28%), Positives = 73/153 (47%), Gaps = 3/153 (1%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ C+ +S DG+ ASG L+ +W+ + + T GH ++ + F + S S
Sbjct: 202 VLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSH 261
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLV--DSGIVLH 1086
DR+V VW +A+NS T GH A+ L +S + R V VW + +S +V +
Sbjct: 262 DRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFY 321
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLA 1119
G I + +N ++ V D SV +W L+
Sbjct: 322 GHQGSIDCIHL-INEEHMVSGADDGSVALWGLS 353
Score = 67.7 bits (158), Expect = 3e-10
Identities = 49/218 (22%), Positives = 96/218 (44%), Gaps = 20/218 (9%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL-----------ADNSPSLTYKGHSSA 1052
L GH ITC+ +P++ + S ++D +++ W + A GHSS
Sbjct: 142 LRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKPPGHSSH 201
Query: 1053 IQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID---VTLNMKYAVLSDG 1109
+ + + SDG+ S DR++ + +W S L++ TG ++ +
Sbjct: 202 VLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSH 261
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLS 1169
D SV++W++A E H + + + V G D +++VWK+ +
Sbjct: 262 DRSVKVWNVAENSYVE---TLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIP-EESQ 317
Query: 1170 QVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDIN 1207
V GH + C + + N+ +VSG+ D ++ +W ++
Sbjct: 318 LVFYGHQGSIDC--IHLINEEHMVSGADDGSVALWGLS 353
Score = 57.6 bits (133), Expect = 3e-07
Identities = 33/150 (22%), Positives = 71/150 (47%), Gaps = 2/150 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ ++ G++L + +W S ++TF GH ++ + R + L + S D S
Sbjct: 205 MAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSHDRS 264
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V VW++ + + H V + A+ V +GG D V + + + + + H
Sbjct: 265 VKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLV-FYGH 323
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
+GS+ + +I + ++ ++G+ DG+V W +
Sbjct: 324 QGSIDCIHLINEEHM-VSGADDGSVALWGL 352
Score = 52.0 bits (119), Expect = 2e-05
Identities = 26/116 (22%), Positives = 52/116 (44%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GHS +LCM ++ + +YL +G +++W+ + H V +A +
Sbjct: 197 GHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQL 256
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
S D +V + ++ + + V L H+ +V ++ + G +DGTV W +
Sbjct: 257 YSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKI 312
Score = 46.0 bits (104), Expect = 0.001
Identities = 33/145 (22%), Positives = 63/145 (43%), Gaps = 11/145 (7%)
Query: 683 SNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWD------LHTLAVKTKILE-- 734
+++ + +GH SI C+ VT + + + ++D S+I W LH + K E
Sbjct: 135 ASADIRVLRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGK 194
Query: 735 ---HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN 791
H + VLC+A + + SG ++I + HR +V+ + + +
Sbjct: 195 PPGHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTH 254
Query: 792 IFITGSQDGTVCTWNVENFTLLSTV 816
+ S D +V WNV + + T+
Sbjct: 255 QLYSTSHDRSVKVWNVAENSYVETL 279
Score = 39.5 bits (88), Expect = 0.087
Identities = 21/115 (18%), Positives = 46/115 (40%), Gaps = 1/115 (0%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H+ + C A+++D +++ +G + +W+ + GH D V+ +A Q+
Sbjct: 198 HSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFR-RGTHQL 256
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
S S D ++ VW++ V + + D T+ +W+
Sbjct: 257 YSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWK 311
Score = 38.3 bits (85), Expect = 0.20
Identities = 29/134 (21%), Positives = 53/134 (39%), Gaps = 12/134 (8%)
Query: 1124 SEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL----------- 1172
S D R H ITC +T D + + + D S+ W ++ G+ V+
Sbjct: 136 SADIRVLRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKP 195
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGT 1232
GHS V C+A+S K + SG +++W+ + V+ +
Sbjct: 196 PGHSSHVLCMAISSDGK-YLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTH 254
Query: 1233 IAVSCAEDKTLIIW 1246
S + D+++ +W
Sbjct: 255 QLYSTSHDRSVKVW 268
Score = 36.7 bits (81), Expect = 0.61
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 983 SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
+G G VRVW++ Q GH G I C+ N ++SG++D +V +W L+ P
Sbjct: 300 AGGRDGTVRVWKIPEES-QLVFYGHQGSIDCIHLI-NEEHMVSGADDGSVALWGLSKKRP 357
>BC001113-1|AAH01113.1| 475|Homo sapiens RRP9, small subunit (SSU)
processome component, homolog (yeast) protein.
Length = 475
Score = 70.1 bits (164), Expect = 5e-11
Identities = 44/153 (28%), Positives = 73/153 (47%), Gaps = 3/153 (1%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ C+ +S DG+ ASG L+ +W+ + + T GH ++ + F + S S
Sbjct: 202 VLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSH 261
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLV--DSGIVLH 1086
DR+V VW +A+NS T GH A+ L +S + R V VW + +S +V +
Sbjct: 262 DRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFY 321
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLA 1119
G I + +N ++ V D SV +W L+
Sbjct: 322 GHQGSIDCIHL-INEEHMVSGADDGSVALWGLS 353
Score = 67.7 bits (158), Expect = 3e-10
Identities = 49/218 (22%), Positives = 96/218 (44%), Gaps = 20/218 (9%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL-----------ADNSPSLTYKGHSSA 1052
L GH ITC+ +P++ + S ++D +++ W + A GHSS
Sbjct: 142 LRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKPPGHSSH 201
Query: 1053 IQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID---VTLNMKYAVLSDG 1109
+ + + SDG+ S DR++ + +W S L++ TG ++ +
Sbjct: 202 VLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSH 261
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLS 1169
D SV++W++A E H + + + V G D +++VWK+ +
Sbjct: 262 DRSVKVWNVAENSYVE---TLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIP-EESQ 317
Query: 1170 QVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDIN 1207
V GH + C + + N+ +VSG+ D ++ +W ++
Sbjct: 318 LVFYGHQGSIDC--IHLINEEHMVSGADDGSVALWGLS 353
Score = 57.6 bits (133), Expect = 3e-07
Identities = 33/150 (22%), Positives = 71/150 (47%), Gaps = 2/150 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ ++ G++L + +W S ++TF GH ++ + R + L + S D S
Sbjct: 205 MAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSHDRS 264
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V VW++ + + H V + A+ V +GG D V + + + + + H
Sbjct: 265 VKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLV-FYGH 323
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
+GS+ + +I + ++ ++G+ DG+V W +
Sbjct: 324 QGSIDCIHLINEEHM-VSGADDGSVALWGL 352
Score = 52.0 bits (119), Expect = 2e-05
Identities = 26/116 (22%), Positives = 52/116 (44%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GHS +LCM ++ + +YL +G +++W+ + H V +A +
Sbjct: 197 GHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQL 256
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
S D +V + ++ + + V L H+ +V ++ + G +DGTV W +
Sbjct: 257 YSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKI 312
Score = 46.0 bits (104), Expect = 0.001
Identities = 33/145 (22%), Positives = 63/145 (43%), Gaps = 11/145 (7%)
Query: 683 SNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWD------LHTLAVKTKILE-- 734
+++ + +GH SI C+ VT + + + ++D S+I W LH + K E
Sbjct: 135 ASADIRVLRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGK 194
Query: 735 ---HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN 791
H + VLC+A + + SG ++I + HR +V+ + + +
Sbjct: 195 PPGHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTH 254
Query: 792 IFITGSQDGTVCTWNVENFTLLSTV 816
+ S D +V WNV + + T+
Sbjct: 255 QLYSTSHDRSVKVWNVAENSYVETL 279
Score = 39.5 bits (88), Expect = 0.087
Identities = 21/115 (18%), Positives = 46/115 (40%), Gaps = 1/115 (0%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H+ + C A+++D +++ +G + +W+ + GH D V+ +A Q+
Sbjct: 198 HSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFR-RGTHQL 256
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
S S D ++ VW++ V + + D T+ +W+
Sbjct: 257 YSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWK 311
Score = 38.3 bits (85), Expect = 0.20
Identities = 29/134 (21%), Positives = 53/134 (39%), Gaps = 12/134 (8%)
Query: 1124 SEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL----------- 1172
S D R H ITC +T D + + + D S+ W ++ G+ V+
Sbjct: 136 SADIRVLRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKP 195
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGT 1232
GHS V C+A+S K + SG +++W+ + V+ +
Sbjct: 196 PGHSSHVLCMAISSDGK-YLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTH 254
Query: 1233 IAVSCAEDKTLIIW 1246
S + D+++ +W
Sbjct: 255 QLYSTSHDRSVKVW 268
Score = 36.7 bits (81), Expect = 0.61
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 983 SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
+G G VRVW++ Q GH G I C+ N ++SG++D +V +W L+ P
Sbjct: 300 AGGRDGTVRVWKIPEES-QLVFYGHQGSIDCIHLI-NEEHMVSGADDGSVALWGLSKKRP 357
>AJ001340-1|CAA04687.1| 475|Homo sapiens U3 snoRNP associated 55 kDa
protein protein.
Length = 475
Score = 70.1 bits (164), Expect = 5e-11
Identities = 44/153 (28%), Positives = 73/153 (47%), Gaps = 3/153 (1%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ C+ +S DG+ ASG L+ +W+ + + T GH ++ + F + S S
Sbjct: 202 VLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSH 261
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLV--DSGIVLH 1086
DR+V VW +A+NS T GH A+ L +S + R V VW + +S +V +
Sbjct: 262 DRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFY 321
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLA 1119
G I + +N ++ V D SV +W L+
Sbjct: 322 GHQGSIDCIHL-INEEHMVSGADDGSVALWGLS 353
Score = 67.7 bits (158), Expect = 3e-10
Identities = 49/218 (22%), Positives = 96/218 (44%), Gaps = 20/218 (9%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL-----------ADNSPSLTYKGHSSA 1052
L GH ITC+ +P++ + S ++D +++ W + A GHSS
Sbjct: 142 LRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKPPGHSSH 201
Query: 1053 IQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID---VTLNMKYAVLSDG 1109
+ + + SDG+ S DR++ + +W S L++ TG ++ +
Sbjct: 202 VLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSH 261
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLS 1169
D SV++W++A E H + + + V G D +++VWK+ +
Sbjct: 262 DRSVKVWNVAENSYVE---TLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIP-EESQ 317
Query: 1170 QVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDIN 1207
V GH + C + + N+ +VSG+ D ++ +W ++
Sbjct: 318 LVFYGHQGSIDC--IHLINEEHMVSGADDGSVALWGLS 353
Score = 57.6 bits (133), Expect = 3e-07
Identities = 33/150 (22%), Positives = 71/150 (47%), Gaps = 2/150 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ ++ G++L + +W S ++TF GH ++ + R + L + S D S
Sbjct: 205 MAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSHDRS 264
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
V VW++ + + H V + A+ V +GG D V + + + + + H
Sbjct: 265 VKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLV-FYGH 323
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
+GS+ + +I + ++ ++G+ DG+V W +
Sbjct: 324 QGSIDCIHLINEEHM-VSGADDGSVALWGL 352
Score = 52.0 bits (119), Expect = 2e-05
Identities = 26/116 (22%), Positives = 52/116 (44%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GHS +LCM ++ + +YL +G +++W+ + H V +A +
Sbjct: 197 GHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQL 256
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
S D +V + ++ + + V L H+ +V ++ + G +DGTV W +
Sbjct: 257 YSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKI 312
Score = 46.0 bits (104), Expect = 0.001
Identities = 33/145 (22%), Positives = 63/145 (43%), Gaps = 11/145 (7%)
Query: 683 SNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWD------LHTLAVKTKILE-- 734
+++ + +GH SI C+ VT + + + ++D S+I W LH + K E
Sbjct: 135 ASADIRVLRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGK 194
Query: 735 ---HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN 791
H + VLC+A + + SG ++I + HR +V+ + + +
Sbjct: 195 PPGHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTH 254
Query: 792 IFITGSQDGTVCTWNVENFTLLSTV 816
+ S D +V WNV + + T+
Sbjct: 255 QLYSTSHDRSVKVWNVAENSYVETL 279
Score = 39.5 bits (88), Expect = 0.087
Identities = 21/115 (18%), Positives = 46/115 (40%), Gaps = 1/115 (0%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H+ + C A+++D +++ +G + +W+ + GH D V+ +A Q+
Sbjct: 198 HSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFR-RGTHQL 256
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
S S D ++ VW++ V + + D T+ +W+
Sbjct: 257 YSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWK 311
Score = 38.3 bits (85), Expect = 0.20
Identities = 29/134 (21%), Positives = 53/134 (39%), Gaps = 12/134 (8%)
Query: 1124 SEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL----------- 1172
S D R H ITC +T D + + + D S+ W ++ G+ V+
Sbjct: 136 SADIRVLRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKP 195
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGT 1232
GHS V C+A+S K + SG +++W+ + V+ +
Sbjct: 196 PGHSSHVLCMAISSDGK-YLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTH 254
Query: 1233 IAVSCAEDKTLIIW 1246
S + D+++ +W
Sbjct: 255 QLYSTSHDRSVKVW 268
Score = 36.7 bits (81), Expect = 0.61
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 983 SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
+G G VRVW++ Q GH G I C+ N ++SG++D +V +W L+ P
Sbjct: 300 AGGRDGTVRVWKIPEES-QLVFYGHQGSIDCIHLI-NEEHMVSGADDGSVALWGLSKKRP 357
>M95627-1|AAA68889.1| 452|Homo sapiens angio-associated migratory
cell protein protein.
Length = 452
Score = 69.7 bits (163), Expect = 7e-11
Identities = 68/302 (22%), Positives = 119/302 (39%), Gaps = 20/302 (6%)
Query: 992 VWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
VW+LS L GH +TC FS ++ LV +G + VWQ+ +++ +
Sbjct: 136 VWRLSDGELLFECAGHKDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEEVWSFE--AG 193
Query: 1052 AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGI--VLHSATGPSASIDVTLNMKYAVLSDG 1109
++ + ++ N +W V +G P+ V + K AV+
Sbjct: 194 DLEWMEWHPRAPVLLAGTADGNTWMWKVPNGDCKTFQGPNCPATCGRVLPDGKRAVVGYE 253
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKL- 1168
D ++RIW L G + + H +TC A D ++TGS+D K+ GK+
Sbjct: 254 DGTIRIWDLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQAKLVSATTGKVV 313
Query: 1169 ---------SQVLVGHSDIVTCVAVSITNKTQVVS----GSWDCNLIVWDINTXXXXXXX 1215
SQ +G + +V V+ G D L ++D+ T
Sbjct: 314 GVFRPETVASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLATQTLRHQC 373
Query: 1216 XXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH-VPLLGFQITSDCAR 1274
V + G + +C+ D + +W+ + G LT + H +L F ++ D +
Sbjct: 374 QHQSGIVQLLWEAGT-AVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASL 432
Query: 1275 VV 1276
VV
Sbjct: 433 VV 434
Score = 64.5 bits (150), Expect = 3e-09
Identities = 49/204 (24%), Positives = 83/204 (40%), Gaps = 10/204 (4%)
Query: 1001 QATLNGHIGHITCVTFSPN-NLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
+ T H + CV+ P N L ++G ED VW+L+D GH ++
Sbjct: 102 EVTFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFS 161
Query: 1060 SDGRRAMSSDRARNVHVWLVDSGIVLHS-ATGPSASIDVTLNMKYAVLSDGDNSVRIWSL 1118
D + D + + VW VD+ + S G ++ + D + +W +
Sbjct: 162 HDSTLVATGDMSGLLKVWQVDTKEEVWSFEAGDLEWMEWHPRAPVLLAGTADGNTWMWKV 221
Query: 1119 AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL---VGH 1175
GD + TC + D + V G D ++++W L G VL GH
Sbjct: 222 PNGDCKTFQGPNCP----ATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGH 277
Query: 1176 SDIVTCVAVSITNKTQVVSGSWDC 1199
+TCVA + + + +++GS DC
Sbjct: 278 QGPLTCVAAN-QDGSLILTGSVDC 300
Score = 51.6 bits (118), Expect = 2e-05
Identities = 81/378 (21%), Positives = 133/378 (35%), Gaps = 26/378 (6%)
Query: 668 VLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYL-LTGSEDTSVIVWDLHTL 726
VL P G +S+V TF HS S+ C+ + ++ L +TG ED VW L
Sbjct: 84 VLEPQEGVVGSMEGPDDSEV-TFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDG 142
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
+ + H V C A + S +++ GD S ++ VD G + ++
Sbjct: 143 ELLFECAGHKDSVTC-AGFSHDSTLVATGDMSGLLKVWQVD-TKEEVWSFEAGDLEWMEW 200
Query: 787 IQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLR 846
+ + G+ DG W V N + P V D + D + +
Sbjct: 201 HPRAPVLLAGTADGNTWMWKVPNGDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIW 260
Query: 847 TFITGTYLHPLK---RHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT----X 899
G+ +H LK H+ + C D S + G D + L S + +++
Sbjct: 261 DLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQAKLVSATTGKVVGVFRPET 320
Query: 900 XXXXXXXXXXXXXXXXFLLAAGGNRVTIYSF--HTEDNLTNFRPTKQMKRRQTKSTTNIT 957
+ + G V + + + L + Q R Q + + I
Sbjct: 321 VASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLATQTLRHQCQHQSGIV 380
Query: 958 LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFS 1017
L E + +C S DG +VR+W T RL GH I S
Sbjct: 381 QLLWEAGTAVVYTC---SLDG----------IVRLWDARTGRLLTDYRGHTAEILDFALS 427
Query: 1018 PNNLLVLSGSEDRTVVVW 1035
+ LV++ S D V+
Sbjct: 428 KDASLVVTTSGDHKAKVF 445
Score = 51.2 bits (117), Expect = 3e-05
Identities = 29/122 (23%), Positives = 58/122 (47%), Gaps = 3/122 (2%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
++C S D L A+G GL++VWQ+ T + + G + + + P ++L+G+
Sbjct: 155 VTCAGFSHDSTLVATGDMSGLLKVWQVDTK--EEVWSFEAGDLEWMEWHPRAPVLLAGTA 212
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D +W++ N T++G + ++ DG+RA+ + +W + G +H
Sbjct: 213 DGNTWMWKV-PNGDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVL 271
Query: 1089 TG 1090
G
Sbjct: 272 KG 273
Score = 47.6 bits (108), Expect = 3e-04
Identities = 54/247 (21%), Positives = 99/247 (40%), Gaps = 23/247 (9%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVW 721
P L+ + G+ +W + N TF+G + C V + + + G ED ++ +W
Sbjct: 202 PRAPVLLAGTADGNTWMWKV-PNGDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIW 260
Query: 722 DLHT---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL---- 774
DL + V H P+ CVAA + SL+++G D + S G +V
Sbjct: 261 DLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQAKLVSATTGKVVGVFRPET 320
Query: 775 -----------DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV--TAGVP 821
+ SV S+ + G DGT+ +++ TL +G+
Sbjct: 321 VASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLATQTLRHQCQHQSGIV 380
Query: 822 IHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCA 881
+++ V+ +L D + L TG L + H A++ F ++ D+S V
Sbjct: 381 QLLWEAGTAVVYTCSL--DGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASLVVTTSG 438
Query: 882 DQRIYLY 888
D + ++
Sbjct: 439 DHKAKVF 445
Score = 40.7 bits (91), Expect = 0.038
Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 3/60 (5%)
Query: 659 QLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFK---GHSGSILCMCVTRESQYLLTGSED 715
++ P G+ V+ G ++W + S +H K GH G + C+ ++ +LTGS D
Sbjct: 240 RVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVD 299
Score = 34.3 bits (75), Expect = 3.3
Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 1/99 (1%)
Query: 1160 VWKLDGGKLSQVLVG-HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXX 1218
V ++G S+V HS V CV++ T V+G D VW ++
Sbjct: 92 VGSMEGPDDSEVTFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGH 151
Query: 1219 XXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSF 1257
VTC + D T+ + L +W+ + SF
Sbjct: 152 KDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEEVWSF 190
>CR456755-1|CAG33036.1| 452|Homo sapiens AAMP protein.
Length = 452
Score = 69.7 bits (163), Expect = 7e-11
Identities = 68/302 (22%), Positives = 119/302 (39%), Gaps = 20/302 (6%)
Query: 992 VWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
VW+LS L GH +TC FS ++ LV +G + VWQ+ +++ +
Sbjct: 136 VWRLSDGELLFECAGHKDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEEVWSFE--AG 193
Query: 1052 AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGI--VLHSATGPSASIDVTLNMKYAVLSDG 1109
++ + ++ N +W V +G P+ V + K AV+
Sbjct: 194 DLEWMEWHPRAPVLLAGTADGNTWMWKVPNGDCKTFQGPNCPATCGRVLPDGKRAVVGYE 253
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKL- 1168
D ++RIW L G + + H +TC A D ++TGS+D K+ GK+
Sbjct: 254 DGTIRIWDLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQAKLVSATTGKVV 313
Query: 1169 ---------SQVLVGHSDIVTCVAVSITNKTQVVS----GSWDCNLIVWDINTXXXXXXX 1215
SQ +G + +V V+ G D L ++D+ T
Sbjct: 314 GVFRPETVASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLATQTLRHQC 373
Query: 1216 XXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH-VPLLGFQITSDCAR 1274
V + G + +C+ D + +W+ + G LT + H +L F ++ D +
Sbjct: 374 QHQSGIVQLLWEAGT-AVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASL 432
Query: 1275 VV 1276
VV
Sbjct: 433 VV 434
Score = 64.5 bits (150), Expect = 3e-09
Identities = 49/204 (24%), Positives = 83/204 (40%), Gaps = 10/204 (4%)
Query: 1001 QATLNGHIGHITCVTFSPN-NLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
+ T H + CV+ P N L ++G ED VW+L+D GH ++
Sbjct: 102 EVTFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFS 161
Query: 1060 SDGRRAMSSDRARNVHVWLVDSGIVLHS-ATGPSASIDVTLNMKYAVLSDGDNSVRIWSL 1118
D + D + + VW VD+ + S G ++ + D + +W +
Sbjct: 162 HDSTLVATGDMSGLLKVWQVDTKEEVWSFEAGDLEWMEWHPRAPVLLAGTADGNTWMWKV 221
Query: 1119 AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL---VGH 1175
GD + TC + D + V G D ++++W L G VL GH
Sbjct: 222 PNGDCKTFQGPNCP----ATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGH 277
Query: 1176 SDIVTCVAVSITNKTQVVSGSWDC 1199
+TCVA + + + +++GS DC
Sbjct: 278 QGPLTCVAAN-QDGSLILTGSVDC 300
Score = 51.6 bits (118), Expect = 2e-05
Identities = 81/378 (21%), Positives = 133/378 (35%), Gaps = 26/378 (6%)
Query: 668 VLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYL-LTGSEDTSVIVWDLHTL 726
VL P G +S+V TF HS S+ C+ + ++ L +TG ED VW L
Sbjct: 84 VLEPQEGVVGSMEGPDDSEV-TFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDG 142
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
+ + H V C A + S +++ GD S ++ VD G + ++
Sbjct: 143 ELLFECAGHKDSVTC-AGFSHDSTLVATGDMSGLLKVWQVD-TKEEVWSFEAGDLEWMEW 200
Query: 787 IQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLR 846
+ + G+ DG W V N + P V D + D + +
Sbjct: 201 HPRAPVLLAGTADGNTWMWKVPNGDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIW 260
Query: 847 TFITGTYLHPLK---RHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT----X 899
G+ +H LK H+ + C D S + G D + L S + +++
Sbjct: 261 DLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQAKLVSATTGKVVGVFRPET 320
Query: 900 XXXXXXXXXXXXXXXXFLLAAGGNRVTIYSF--HTEDNLTNFRPTKQMKRRQTKSTTNIT 957
+ + G V + + + L + Q R Q + + I
Sbjct: 321 VASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLATQTLRHQCQHQSGIV 380
Query: 958 LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFS 1017
L E + +C S DG +VR+W T RL GH I S
Sbjct: 381 QLLWEAGTAVVYTC---SLDG----------IVRLWDARTGRLLTDYRGHTAEILDFALS 427
Query: 1018 PNNLLVLSGSEDRTVVVW 1035
+ LV++ S D V+
Sbjct: 428 KDASLVVTTSGDHKAKVF 445
Score = 51.2 bits (117), Expect = 3e-05
Identities = 29/122 (23%), Positives = 58/122 (47%), Gaps = 3/122 (2%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
++C S D L A+G GL++VWQ+ T + + G + + + P ++L+G+
Sbjct: 155 VTCAGFSHDSTLVATGDMSGLLKVWQVDTK--EEVWSFEAGDLEWMEWHPRAPVLLAGTA 212
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D +W++ N T++G + ++ DG+RA+ + +W + G +H
Sbjct: 213 DGNTWMWKV-PNGDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVL 271
Query: 1089 TG 1090
G
Sbjct: 272 KG 273
Score = 47.6 bits (108), Expect = 3e-04
Identities = 54/247 (21%), Positives = 99/247 (40%), Gaps = 23/247 (9%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVW 721
P L+ + G+ +W + N TF+G + C V + + + G ED ++ +W
Sbjct: 202 PRAPVLLAGTADGNTWMWKV-PNGDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIW 260
Query: 722 DLHT---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL---- 774
DL + V H P+ CVAA + SL+++G D + S G +V
Sbjct: 261 DLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQAKLVSATTGKVVGVFRPET 320
Query: 775 -----------DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV--TAGVP 821
+ SV S+ + G DGT+ +++ TL +G+
Sbjct: 321 VASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLATQTLRHQCQHQSGIV 380
Query: 822 IHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCA 881
+++ V+ +L D + L TG L + H A++ F ++ D+S V
Sbjct: 381 QLLWEAGTAVVYTCSL--DGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASLVVTTSG 438
Query: 882 DQRIYLY 888
D + ++
Sbjct: 439 DHKAKVF 445
Score = 40.7 bits (91), Expect = 0.038
Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 3/60 (5%)
Query: 659 QLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFK---GHSGSILCMCVTRESQYLLTGSED 715
++ P G+ V+ G ++W + S +H K GH G + C+ ++ +LTGS D
Sbjct: 240 RVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVD 299
Score = 34.3 bits (75), Expect = 3.3
Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 1/99 (1%)
Query: 1160 VWKLDGGKLSQVLVG-HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXX 1218
V ++G S+V HS V CV++ T V+G D VW ++
Sbjct: 92 VGSMEGPDDSEVTFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGH 151
Query: 1219 XXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSF 1257
VTC + D T+ + L +W+ + SF
Sbjct: 152 KDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEEVWSF 190
>BC039866-1|AAH39866.2| 434|Homo sapiens angio-associated, migratory
cell protein protein.
Length = 434
Score = 69.7 bits (163), Expect = 7e-11
Identities = 68/302 (22%), Positives = 119/302 (39%), Gaps = 20/302 (6%)
Query: 992 VWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
VW+LS L GH +TC FS ++ LV +G + VWQ+ +++ +
Sbjct: 118 VWRLSDGELLFECAGHKDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEEVWSFE--AG 175
Query: 1052 AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGI--VLHSATGPSASIDVTLNMKYAVLSDG 1109
++ + ++ N +W V +G P+ V + K AV+
Sbjct: 176 DLEWMEWHPRAPVLLAGTADGNTWMWKVPNGDCKTFQGPNCPATCGRVLPDGKRAVVGYE 235
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKL- 1168
D ++RIW L G + + H +TC A D ++TGS+D K+ GK+
Sbjct: 236 DGTIRIWDLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQAKLVSATTGKVV 295
Query: 1169 ---------SQVLVGHSDIVTCVAVSITNKTQVVS----GSWDCNLIVWDINTXXXXXXX 1215
SQ +G + +V V+ G D L ++D+ T
Sbjct: 296 GVFRPETVASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLATQTLRHQC 355
Query: 1216 XXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH-VPLLGFQITSDCAR 1274
V + G + +C+ D + +W+ + G LT + H +L F ++ D +
Sbjct: 356 QHQSGIVQLLWEAGT-AVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASL 414
Query: 1275 VV 1276
VV
Sbjct: 415 VV 416
Score = 64.5 bits (150), Expect = 3e-09
Identities = 49/204 (24%), Positives = 83/204 (40%), Gaps = 10/204 (4%)
Query: 1001 QATLNGHIGHITCVTFSPN-NLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
+ T H + CV+ P N L ++G ED VW+L+D GH ++
Sbjct: 84 EVTFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFS 143
Query: 1060 SDGRRAMSSDRARNVHVWLVDSGIVLHS-ATGPSASIDVTLNMKYAVLSDGDNSVRIWSL 1118
D + D + + VW VD+ + S G ++ + D + +W +
Sbjct: 144 HDSTLVATGDMSGLLKVWQVDTKEEVWSFEAGDLEWMEWHPRAPVLLAGTADGNTWMWKV 203
Query: 1119 AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL---VGH 1175
GD + TC + D + V G D ++++W L G VL GH
Sbjct: 204 PNGDCKTFQGPNCP----ATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGH 259
Query: 1176 SDIVTCVAVSITNKTQVVSGSWDC 1199
+TCVA + + + +++GS DC
Sbjct: 260 QGPLTCVAAN-QDGSLILTGSVDC 282
Score = 51.6 bits (118), Expect = 2e-05
Identities = 81/378 (21%), Positives = 133/378 (35%), Gaps = 26/378 (6%)
Query: 668 VLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYL-LTGSEDTSVIVWDLHTL 726
VL P G +S+V TF HS S+ C+ + ++ L +TG ED VW L
Sbjct: 66 VLEPQEGVVGSMEGPDDSEV-TFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDG 124
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
+ + H V C A + S +++ GD S ++ VD G + ++
Sbjct: 125 ELLFECAGHKDSVTC-AGFSHDSTLVATGDMSGLLKVWQVD-TKEEVWSFEAGDLEWMEW 182
Query: 787 IQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLR 846
+ + G+ DG W V N + P V D + D + +
Sbjct: 183 HPRAPVLLAGTADGNTWMWKVPNGDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIW 242
Query: 847 TFITGTYLHPLK---RHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT----X 899
G+ +H LK H+ + C D S + G D + L S + +++
Sbjct: 243 DLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQAKLVSATTGKVVGVFRPET 302
Query: 900 XXXXXXXXXXXXXXXXFLLAAGGNRVTIYSF--HTEDNLTNFRPTKQMKRRQTKSTTNIT 957
+ + G V + + + L + Q R Q + + I
Sbjct: 303 VASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLATQTLRHQCQHQSGIV 362
Query: 958 LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFS 1017
L E + +C S DG +VR+W T RL GH I S
Sbjct: 363 QLLWEAGTAVVYTC---SLDG----------IVRLWDARTGRLLTDYRGHTAEILDFALS 409
Query: 1018 PNNLLVLSGSEDRTVVVW 1035
+ LV++ S D V+
Sbjct: 410 KDASLVVTTSGDHKAKVF 427
Score = 51.2 bits (117), Expect = 3e-05
Identities = 29/122 (23%), Positives = 58/122 (47%), Gaps = 3/122 (2%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
++C S D L A+G GL++VWQ+ T + + G + + + P ++L+G+
Sbjct: 137 VTCAGFSHDSTLVATGDMSGLLKVWQVDTK--EEVWSFEAGDLEWMEWHPRAPVLLAGTA 194
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D +W++ N T++G + ++ DG+RA+ + +W + G +H
Sbjct: 195 DGNTWMWKV-PNGDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVL 253
Query: 1089 TG 1090
G
Sbjct: 254 KG 255
Score = 47.6 bits (108), Expect = 3e-04
Identities = 54/247 (21%), Positives = 99/247 (40%), Gaps = 23/247 (9%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVW 721
P L+ + G+ +W + N TF+G + C V + + + G ED ++ +W
Sbjct: 184 PRAPVLLAGTADGNTWMWKV-PNGDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIW 242
Query: 722 DLHT---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL---- 774
DL + V H P+ CVAA + SL+++G D + S G +V
Sbjct: 243 DLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQAKLVSATTGKVVGVFRPET 302
Query: 775 -----------DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV--TAGVP 821
+ SV S+ + G DGT+ +++ TL +G+
Sbjct: 303 VASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLATQTLRHQCQHQSGIV 362
Query: 822 IHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCA 881
+++ V+ +L D + L TG L + H A++ F ++ D+S V
Sbjct: 363 QLLWEAGTAVVYTCSL--DGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASLVVTTSG 420
Query: 882 DQRIYLY 888
D + ++
Sbjct: 421 DHKAKVF 427
Score = 40.7 bits (91), Expect = 0.038
Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 3/60 (5%)
Query: 659 QLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFK---GHSGSILCMCVTRESQYLLTGSED 715
++ P G+ V+ G ++W + S +H K GH G + C+ ++ +LTGS D
Sbjct: 222 RVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVD 281
Score = 34.3 bits (75), Expect = 3.3
Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 1/99 (1%)
Query: 1160 VWKLDGGKLSQVLVG-HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXX 1218
V ++G S+V HS V CV++ T V+G D VW ++
Sbjct: 74 VGSMEGPDDSEVTFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGH 133
Query: 1219 XXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSF 1257
VTC + D T+ + L +W+ + SF
Sbjct: 134 KDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEEVWSF 172
>BC020244-1|AAH20244.1| 429|Homo sapiens Similar to angio-associated,
migratory cell protein protein.
Length = 429
Score = 69.7 bits (163), Expect = 7e-11
Identities = 68/302 (22%), Positives = 119/302 (39%), Gaps = 20/302 (6%)
Query: 992 VWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
VW+LS L GH +TC FS ++ LV +G + VWQ+ +++ +
Sbjct: 113 VWRLSDGELLFECAGHKDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEEVWSFE--AG 170
Query: 1052 AIQTLLMMSDGRRAMSSDRARNVHVWLVDSGI--VLHSATGPSASIDVTLNMKYAVLSDG 1109
++ + ++ N +W V +G P+ V + K AV+
Sbjct: 171 DLEWMEWHPRAPVLLAGTADGNTWMWKVPNGDCKTFQGPNCPATCGRVLPDGKRAVVGYE 230
Query: 1110 DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKL- 1168
D ++RIW L G + + H +TC A D ++TGS+D K+ GK+
Sbjct: 231 DGTIRIWDLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQAKLVSATTGKVV 290
Query: 1169 ---------SQVLVGHSDIVTCVAVSITNKTQVVS----GSWDCNLIVWDINTXXXXXXX 1215
SQ +G + +V V+ G D L ++D+ T
Sbjct: 291 GVFRPETVASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLATQTLRHQC 350
Query: 1216 XXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLH-VPLLGFQITSDCAR 1274
V + G + +C+ D + +W+ + G LT + H +L F ++ D +
Sbjct: 351 QHQSGIVQLLWEAGT-AVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASL 409
Query: 1275 VV 1276
VV
Sbjct: 410 VV 411
Score = 64.5 bits (150), Expect = 3e-09
Identities = 49/204 (24%), Positives = 83/204 (40%), Gaps = 10/204 (4%)
Query: 1001 QATLNGHIGHITCVTFSPN-NLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
+ T H + CV+ P N L ++G ED VW+L+D GH ++
Sbjct: 79 EVTFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFS 138
Query: 1060 SDGRRAMSSDRARNVHVWLVDSGIVLHS-ATGPSASIDVTLNMKYAVLSDGDNSVRIWSL 1118
D + D + + VW VD+ + S G ++ + D + +W +
Sbjct: 139 HDSTLVATGDMSGLLKVWQVDTKEEVWSFEAGDLEWMEWHPRAPVLLAGTADGNTWMWKV 198
Query: 1119 AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL---VGH 1175
GD + TC + D + V G D ++++W L G VL GH
Sbjct: 199 PNGDCKTFQGPNCP----ATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGH 254
Query: 1176 SDIVTCVAVSITNKTQVVSGSWDC 1199
+TCVA + + + +++GS DC
Sbjct: 255 QGPLTCVAAN-QDGSLILTGSVDC 277
Score = 51.6 bits (118), Expect = 2e-05
Identities = 81/378 (21%), Positives = 133/378 (35%), Gaps = 26/378 (6%)
Query: 668 VLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYL-LTGSEDTSVIVWDLHTL 726
VL P G +S+V TF HS S+ C+ + ++ L +TG ED VW L
Sbjct: 61 VLEPQEGVVGSMEGPDDSEV-TFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDG 119
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV 786
+ + H V C A + S +++ GD S ++ VD G + ++
Sbjct: 120 ELLFECAGHKDSVTC-AGFSHDSTLVATGDMSGLLKVWQVD-TKEEVWSFEAGDLEWMEW 177
Query: 787 IQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLR 846
+ + G+ DG W V N + P V D + D + +
Sbjct: 178 HPRAPVLLAGTADGNTWMWKVPNGDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIW 237
Query: 847 TFITGTYLHPLK---RHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT----X 899
G+ +H LK H+ + C D S + G D + L S + +++
Sbjct: 238 DLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQAKLVSATTGKVVGVFRPET 297
Query: 900 XXXXXXXXXXXXXXXXFLLAAGGNRVTIYSF--HTEDNLTNFRPTKQMKRRQTKSTTNIT 957
+ + G V + + + L + Q R Q + + I
Sbjct: 298 VASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLATQTLRHQCQHQSGIV 357
Query: 958 LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFS 1017
L E + +C S DG +VR+W T RL GH I S
Sbjct: 358 QLLWEAGTAVVYTC---SLDG----------IVRLWDARTGRLLTDYRGHTAEILDFALS 404
Query: 1018 PNNLLVLSGSEDRTVVVW 1035
+ LV++ S D V+
Sbjct: 405 KDASLVVTTSGDHKAKVF 422
Score = 51.2 bits (117), Expect = 3e-05
Identities = 29/122 (23%), Positives = 58/122 (47%), Gaps = 3/122 (2%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
++C S D L A+G GL++VWQ+ T + + G + + + P ++L+G+
Sbjct: 132 VTCAGFSHDSTLVATGDMSGLLKVWQVDTK--EEVWSFEAGDLEWMEWHPRAPVLLAGTA 189
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D +W++ N T++G + ++ DG+RA+ + +W + G +H
Sbjct: 190 DGNTWMWKV-PNGDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVL 248
Query: 1089 TG 1090
G
Sbjct: 249 KG 250
Score = 47.6 bits (108), Expect = 3e-04
Identities = 54/247 (21%), Positives = 99/247 (40%), Gaps = 23/247 (9%)
Query: 662 PSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVW 721
P L+ + G+ +W + N TF+G + C V + + + G ED ++ +W
Sbjct: 179 PRAPVLLAGTADGNTWMWKV-PNGDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIW 237
Query: 722 DLHT---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL---- 774
DL + V H P+ CVAA + SL+++G D + S G +V
Sbjct: 238 DLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQAKLVSATTGKVVGVFRPET 297
Query: 775 -----------DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV--TAGVP 821
+ SV S+ + G DGT+ +++ TL +G+
Sbjct: 298 VASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLATQTLRHQCQHQSGIV 357
Query: 822 IHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCA 881
+++ V+ +L D + L TG L + H A++ F ++ D+S V
Sbjct: 358 QLLWEAGTAVVYTCSL--DGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASLVVTTSG 415
Query: 882 DQRIYLY 888
D + ++
Sbjct: 416 DHKAKVF 422
Score = 40.7 bits (91), Expect = 0.038
Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 3/60 (5%)
Query: 659 QLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFK---GHSGSILCMCVTRESQYLLTGSED 715
++ P G+ V+ G ++W + S +H K GH G + C+ ++ +LTGS D
Sbjct: 217 RVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVD 276
Score = 34.3 bits (75), Expect = 3.3
Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 1/99 (1%)
Query: 1160 VWKLDGGKLSQVLVG-HSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXX 1218
V ++G S+V HS V CV++ T V+G D VW ++
Sbjct: 69 VGSMEGPDDSEVTFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGH 128
Query: 1219 XXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSF 1257
VTC + D T+ + L +W+ + SF
Sbjct: 129 KDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEEVWSF 167
>BC018698-1|AAH18698.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA
processing factor 19 homolog (S. cerevisiae) protein.
Length = 504
Score = 69.7 bits (163), Expect = 7e-11
Identities = 58/229 (25%), Positives = 104/229 (45%), Gaps = 12/229 (5%)
Query: 940 RPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHR 999
+P + K RQ S ++ L A ++ + L S ++ G + +V V+ S+ +
Sbjct: 200 KPEELSKYRQVAS--HVGLHSASIPGILALD-LCPSDTNKILTGGADKNVV-VFDKSSEQ 255
Query: 1000 LQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
+ ATL GH +T V F P+ LV S S D T+ +W + + S + H SA+ L +
Sbjct: 256 ILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLH 315
Query: 1060 SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKY---AVLSDG--DNSVR 1114
+ G +SS + + +G VL T ++ +T + + G D+ ++
Sbjct: 316 ATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIK 375
Query: 1115 IWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKL 1163
IW L N + H+ IT A + + ++ T + D S+K+W L
Sbjct: 376 IWDLKERTNVAN---FPGHSGPITSIAFSENGYYLATAADDSSVKLWDL 421
Score = 56.0 bits (129), Expect = 9e-07
Identities = 49/235 (20%), Positives = 99/235 (42%), Gaps = 5/235 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKV-HTFKGHSGSILCMCVTRESQYLLTGSEDT 716
L L PS + +L A + S+ ++ T KGH+ + + + + S D
Sbjct: 227 LDLCPSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDA 286
Query: 717 SVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL-D 775
++ +W + + + H + V ++ ++S DD + + G ++TK+ D
Sbjct: 287 TIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTD 346
Query: 776 HHRG-SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA-GVPIHIFDVTDDNVF 833
G S+T + DG IF TG+ D + W+++ T ++ PI +++ +
Sbjct: 347 ETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYY 406
Query: 834 LLTLQGDNELHLRTFITGTYLHPLK-RHKAKVKCFCVAHDSSRVAVGCADQRIYL 887
L T D+ + L L+ + +VK + +A+G D +IY+
Sbjct: 407 LATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYI 461
Score = 49.2 bits (112), Expect = 1e-04
Identities = 50/245 (20%), Positives = 96/245 (39%), Gaps = 10/245 (4%)
Query: 693 HSGSI-----LCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVN 747
HS SI L +C + ++ +LTG D +V+V+D + + + H V V +
Sbjct: 217 HSASIPGILALDLCPS-DTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPS 275
Query: 748 RSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
+ LV S D+ + I S+ + + V + H +VT + + G+ ++ S D ++
Sbjct: 276 QDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDI 335
Query: 808 ENFTLLSTV---TAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKV 864
+ +L+ V T+G + D + T D+++ + T + H +
Sbjct: 336 QTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPI 395
Query: 865 KCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT-XXXXXXXXXXXXXXXXXFLLAAGGN 923
+ + +A D + L+ L + +T LA GG
Sbjct: 396 TSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGT 455
Query: 924 RVTIY 928
V IY
Sbjct: 456 DVQIY 460
Score = 48.0 bits (109), Expect = 2e-04
Identities = 36/129 (27%), Positives = 54/129 (41%), Gaps = 7/129 (5%)
Query: 659 QLAPSGQHLVLAPSAGDPQL--WHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDT 716
Q P G L+ D Q+ W + + V F GHSG I + + YL T ++D+
Sbjct: 357 QFHPDG--LIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDS 414
Query: 717 SVIVWDLHTLA-VKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
SV +WDL L KT L++ V + + + + GG D + I +
Sbjct: 415 SVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICK--QWTEILHFT 472
Query: 776 HHRGSVTSV 784
H G T V
Sbjct: 473 EHSGLTTGV 481
Score = 44.4 bits (100), Expect = 0.003
Identities = 43/187 (22%), Positives = 79/187 (42%), Gaps = 10/187 (5%)
Query: 1079 VDSGIVLHSATGPSA-SIDVTLNMKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVS-HAE 1135
V S + LHSA+ P ++D+ + +L+ G D +V ++ +SE ++ H +
Sbjct: 210 VASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVFD----KSSEQILATLKGHTK 265
Query: 1136 RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSG 1195
++T V + S D ++++W + QV+ H VT +++ T ++S
Sbjct: 266 KVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGD-YLLSS 324
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLA 1253
S D DI T +TC + DG I + D + IW+ K
Sbjct: 325 SDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTN 384
Query: 1254 LTSFSLH 1260
+ +F H
Sbjct: 385 VANFPGH 391
Score = 38.7 bits (86), Expect = 0.15
Identities = 38/210 (18%), Positives = 87/210 (41%), Gaps = 11/210 (5%)
Query: 1049 HSSAIQTLLMM----SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
HS++I +L + SD + ++ +NV V+ S +L + G + + + +
Sbjct: 217 HSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQ 276
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
+ D ++RIWS+ + R +H +T +L A ++++ S D
Sbjct: 277 DLVFSASPDATIRIWSVPNASCVQVVR---AHESAVTGLSLHATGDYLLSSSDDQYWAFS 333
Query: 1162 KLDGGK-LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
+ G+ L++V S A + +G+ D + +WD+
Sbjct: 334 DIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSG 393
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
+T + + +G + A+D ++ +W+ ++
Sbjct: 394 PITSIAFSENGYYLATAADDSSVKLWDLRK 423
>BC018665-1|AAH18665.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA
processing factor 19 homolog (S. cerevisiae) protein.
Length = 504
Score = 69.7 bits (163), Expect = 7e-11
Identities = 58/229 (25%), Positives = 104/229 (45%), Gaps = 12/229 (5%)
Query: 940 RPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHR 999
+P + K RQ S ++ L A ++ + L S ++ G + +V V+ S+ +
Sbjct: 200 KPEELSKYRQVAS--HVGLHSASIPGILALD-LCPSDTNKILTGGADKNVV-VFDKSSEQ 255
Query: 1000 LQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
+ ATL GH +T V F P+ LV S S D T+ +W + + S + H SA+ L +
Sbjct: 256 ILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLH 315
Query: 1060 SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKY---AVLSDG--DNSVR 1114
+ G +SS + + +G VL T ++ +T + + G D+ ++
Sbjct: 316 ATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIK 375
Query: 1115 IWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKL 1163
IW L N + H+ IT A + + ++ T + D S+K+W L
Sbjct: 376 IWDLKERTNVAN---FPGHSGPITSIAFSENGYYLATAADDSSVKLWDL 421
Score = 56.0 bits (129), Expect = 9e-07
Identities = 49/235 (20%), Positives = 99/235 (42%), Gaps = 5/235 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKV-HTFKGHSGSILCMCVTRESQYLLTGSEDT 716
L L PS + +L A + S+ ++ T KGH+ + + + + S D
Sbjct: 227 LDLCPSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDA 286
Query: 717 SVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL-D 775
++ +W + + + H + V ++ ++S DD + + G ++TK+ D
Sbjct: 287 TIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTD 346
Query: 776 HHRG-SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA-GVPIHIFDVTDDNVF 833
G S+T + DG IF TG+ D + W+++ T ++ PI +++ +
Sbjct: 347 ETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYY 406
Query: 834 LLTLQGDNELHLRTFITGTYLHPLK-RHKAKVKCFCVAHDSSRVAVGCADQRIYL 887
L T D+ + L L+ + +VK + +A+G D +IY+
Sbjct: 407 LATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYI 461
Score = 49.2 bits (112), Expect = 1e-04
Identities = 50/245 (20%), Positives = 96/245 (39%), Gaps = 10/245 (4%)
Query: 693 HSGSI-----LCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVN 747
HS SI L +C + ++ +LTG D +V+V+D + + + H V V +
Sbjct: 217 HSASIPGILALDLCPS-DTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPS 275
Query: 748 RSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
+ LV S D+ + I S+ + + V + H +VT + + G+ ++ S D ++
Sbjct: 276 QDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDI 335
Query: 808 ENFTLLSTV---TAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKV 864
+ +L+ V T+G + D + T D+++ + T + H +
Sbjct: 336 QTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPI 395
Query: 865 KCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT-XXXXXXXXXXXXXXXXXFLLAAGGN 923
+ + +A D + L+ L + +T LA GG
Sbjct: 396 TSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGT 455
Query: 924 RVTIY 928
V IY
Sbjct: 456 DVQIY 460
Score = 48.0 bits (109), Expect = 2e-04
Identities = 36/129 (27%), Positives = 54/129 (41%), Gaps = 7/129 (5%)
Query: 659 QLAPSGQHLVLAPSAGDPQL--WHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDT 716
Q P G L+ D Q+ W + + V F GHSG I + + YL T ++D+
Sbjct: 357 QFHPDG--LIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDS 414
Query: 717 SVIVWDLHTLA-VKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
SV +WDL L KT L++ V + + + + GG D + I +
Sbjct: 415 SVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICK--QWTEILHFT 472
Query: 776 HHRGSVTSV 784
H G T V
Sbjct: 473 EHSGLTTGV 481
Score = 44.4 bits (100), Expect = 0.003
Identities = 43/187 (22%), Positives = 79/187 (42%), Gaps = 10/187 (5%)
Query: 1079 VDSGIVLHSATGPSA-SIDVTLNMKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVS-HAE 1135
V S + LHSA+ P ++D+ + +L+ G D +V ++ +SE ++ H +
Sbjct: 210 VASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVFD----KSSEQILATLKGHTK 265
Query: 1136 RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSG 1195
++T V + S D ++++W + QV+ H VT +++ T ++S
Sbjct: 266 KVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGD-YLLSS 324
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLA 1253
S D DI T +TC + DG I + D + IW+ K
Sbjct: 325 SDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTN 384
Query: 1254 LTSFSLH 1260
+ +F H
Sbjct: 385 VANFPGH 391
Score = 38.7 bits (86), Expect = 0.15
Identities = 38/210 (18%), Positives = 87/210 (41%), Gaps = 11/210 (5%)
Query: 1049 HSSAIQTLLMM----SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
HS++I +L + SD + ++ +NV V+ S +L + G + + + +
Sbjct: 217 HSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQ 276
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
+ D ++RIWS+ + R +H +T +L A ++++ S D
Sbjct: 277 DLVFSASPDATIRIWSVPNASCVQVVR---AHESAVTGLSLHATGDYLLSSSDDQYWAFS 333
Query: 1162 KLDGGK-LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
+ G+ L++V S A + +G+ D + +WD+
Sbjct: 334 DIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSG 393
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
+T + + +G + A+D ++ +W+ ++
Sbjct: 394 PITSIAFSENGYYLATAADDSSVKLWDLRK 423
>BC008719-1|AAH08719.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA
processing factor 19 homolog (S. cerevisiae) protein.
Length = 504
Score = 69.7 bits (163), Expect = 7e-11
Identities = 58/229 (25%), Positives = 104/229 (45%), Gaps = 12/229 (5%)
Query: 940 RPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHR 999
+P + K RQ S ++ L A ++ + L S ++ G + +V V+ S+ +
Sbjct: 200 KPEELSKYRQVAS--HVGLHSASIPGILALD-LCPSDTNKILTGGADKNVV-VFDKSSEQ 255
Query: 1000 LQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
+ ATL GH +T V F P+ LV S S D T+ +W + + S + H SA+ L +
Sbjct: 256 ILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLH 315
Query: 1060 SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKY---AVLSDG--DNSVR 1114
+ G +SS + + +G VL T ++ +T + + G D+ ++
Sbjct: 316 ATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIK 375
Query: 1115 IWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKL 1163
IW L N + H+ IT A + + ++ T + D S+K+W L
Sbjct: 376 IWDLKERTNVAN---FPGHSGPITSIAFSENGYYLATAADDSSVKLWDL 421
Score = 56.0 bits (129), Expect = 9e-07
Identities = 49/235 (20%), Positives = 99/235 (42%), Gaps = 5/235 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKV-HTFKGHSGSILCMCVTRESQYLLTGSEDT 716
L L PS + +L A + S+ ++ T KGH+ + + + + S D
Sbjct: 227 LDLCPSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDA 286
Query: 717 SVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL-D 775
++ +W + + + H + V ++ ++S DD + + G ++TK+ D
Sbjct: 287 TIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTD 346
Query: 776 HHRG-SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA-GVPIHIFDVTDDNVF 833
G S+T + DG IF TG+ D + W+++ T ++ PI +++ +
Sbjct: 347 ETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYY 406
Query: 834 LLTLQGDNELHLRTFITGTYLHPLK-RHKAKVKCFCVAHDSSRVAVGCADQRIYL 887
L T D+ + L L+ + +VK + +A+G D +IY+
Sbjct: 407 LATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYI 461
Score = 49.2 bits (112), Expect = 1e-04
Identities = 50/245 (20%), Positives = 96/245 (39%), Gaps = 10/245 (4%)
Query: 693 HSGSI-----LCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVN 747
HS SI L +C + ++ +LTG D +V+V+D + + + H V V +
Sbjct: 217 HSASIPGILALDLCPS-DTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPS 275
Query: 748 RSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
+ LV S D+ + I S+ + + V + H +VT + + G+ ++ S D ++
Sbjct: 276 QDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDI 335
Query: 808 ENFTLLSTV---TAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKV 864
+ +L+ V T+G + D + T D+++ + T + H +
Sbjct: 336 QTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPI 395
Query: 865 KCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT-XXXXXXXXXXXXXXXXXFLLAAGGN 923
+ + +A D + L+ L + +T LA GG
Sbjct: 396 TSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGT 455
Query: 924 RVTIY 928
V IY
Sbjct: 456 DVQIY 460
Score = 48.0 bits (109), Expect = 2e-04
Identities = 36/129 (27%), Positives = 54/129 (41%), Gaps = 7/129 (5%)
Query: 659 QLAPSGQHLVLAPSAGDPQL--WHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDT 716
Q P G L+ D Q+ W + + V F GHSG I + + YL T ++D+
Sbjct: 357 QFHPDG--LIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDS 414
Query: 717 SVIVWDLHTLA-VKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
SV +WDL L KT L++ V + + + + GG D + I +
Sbjct: 415 SVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICK--QWTEILHFT 472
Query: 776 HHRGSVTSV 784
H G T V
Sbjct: 473 EHSGLTTGV 481
Score = 44.4 bits (100), Expect = 0.003
Identities = 43/187 (22%), Positives = 79/187 (42%), Gaps = 10/187 (5%)
Query: 1079 VDSGIVLHSATGPSA-SIDVTLNMKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVS-HAE 1135
V S + LHSA+ P ++D+ + +L+ G D +V ++ +SE ++ H +
Sbjct: 210 VASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVFD----KSSEQILATLKGHTK 265
Query: 1136 RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSG 1195
++T V + S D ++++W + QV+ H VT +++ T ++S
Sbjct: 266 KVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGD-YLLSS 324
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLA 1253
S D DI T +TC + DG I + D + IW+ K
Sbjct: 325 SDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTN 384
Query: 1254 LTSFSLH 1260
+ +F H
Sbjct: 385 VANFPGH 391
Score = 38.7 bits (86), Expect = 0.15
Identities = 38/210 (18%), Positives = 87/210 (41%), Gaps = 11/210 (5%)
Query: 1049 HSSAIQTLLMM----SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
HS++I +L + SD + ++ +NV V+ S +L + G + + + +
Sbjct: 217 HSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQ 276
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
+ D ++RIWS+ + R +H +T +L A ++++ S D
Sbjct: 277 DLVFSASPDATIRIWSVPNASCVQVVR---AHESAVTGLSLHATGDYLLSSSDDQYWAFS 333
Query: 1162 KLDGGK-LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
+ G+ L++V S A + +G+ D + +WD+
Sbjct: 334 DIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSG 393
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
+T + + +G + A+D ++ +W+ ++
Sbjct: 394 PITSIAFSENGYYLATAADDSSVKLWDLRK 423
>AJ131186-1|CAB51857.1| 504|Homo sapiens nuclear matrix protein
NMP200 protein.
Length = 504
Score = 69.7 bits (163), Expect = 7e-11
Identities = 58/229 (25%), Positives = 104/229 (45%), Gaps = 12/229 (5%)
Query: 940 RPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHR 999
+P + K RQ S ++ L A ++ + L S ++ G + +V V+ S+ +
Sbjct: 200 KPEELSKYRQVAS--HVGLHSASIPGILALD-LCPSDTNKILTGGADKNVV-VFDKSSEQ 255
Query: 1000 LQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
+ ATL GH +T V F P+ LV S S D T+ +W + + S + H SA+ L +
Sbjct: 256 ILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLH 315
Query: 1060 SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKY---AVLSDG--DNSVR 1114
+ G +SS + + +G VL T ++ +T + + G D+ ++
Sbjct: 316 ATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIK 375
Query: 1115 IWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKL 1163
IW L N + H+ IT A + + ++ T + D S+K+W L
Sbjct: 376 IWDLKERTNVAN---FPGHSGPITSIAFSENGYYLATAADDSSVKLWDL 421
Score = 56.0 bits (129), Expect = 9e-07
Identities = 49/235 (20%), Positives = 99/235 (42%), Gaps = 5/235 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKV-HTFKGHSGSILCMCVTRESQYLLTGSEDT 716
L L PS + +L A + S+ ++ T KGH+ + + + + S D
Sbjct: 227 LDLCPSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDA 286
Query: 717 SVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL-D 775
++ +W + + + H + V ++ ++S DD + + G ++TK+ D
Sbjct: 287 TIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTD 346
Query: 776 HHRG-SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA-GVPIHIFDVTDDNVF 833
G S+T + DG IF TG+ D + W+++ T ++ PI +++ +
Sbjct: 347 ETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYY 406
Query: 834 LLTLQGDNELHLRTFITGTYLHPLK-RHKAKVKCFCVAHDSSRVAVGCADQRIYL 887
L T D+ + L L+ + +VK + +A+G D +IY+
Sbjct: 407 LATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYI 461
Score = 49.2 bits (112), Expect = 1e-04
Identities = 50/245 (20%), Positives = 96/245 (39%), Gaps = 10/245 (4%)
Query: 693 HSGSI-----LCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVN 747
HS SI L +C + ++ +LTG D +V+V+D + + + H V V +
Sbjct: 217 HSASIPGILALDLCPS-DTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPS 275
Query: 748 RSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
+ LV S D+ + I S+ + + V + H +VT + + G+ ++ S D ++
Sbjct: 276 QDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDI 335
Query: 808 ENFTLLSTV---TAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKV 864
+ +L+ V T+G + D + T D+++ + T + H +
Sbjct: 336 QTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPI 395
Query: 865 KCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT-XXXXXXXXXXXXXXXXXFLLAAGGN 923
+ + +A D + L+ L + +T LA GG
Sbjct: 396 TSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGT 455
Query: 924 RVTIY 928
V IY
Sbjct: 456 DVQIY 460
Score = 48.0 bits (109), Expect = 2e-04
Identities = 36/129 (27%), Positives = 54/129 (41%), Gaps = 7/129 (5%)
Query: 659 QLAPSGQHLVLAPSAGDPQL--WHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDT 716
Q P G L+ D Q+ W + + V F GHSG I + + YL T ++D+
Sbjct: 357 QFHPDG--LIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDS 414
Query: 717 SVIVWDLHTLA-VKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
SV +WDL L KT L++ V + + + + GG D + I +
Sbjct: 415 SVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICK--QWTEILHFT 472
Query: 776 HHRGSVTSV 784
H G T V
Sbjct: 473 EHSGLTTGV 481
Score = 44.4 bits (100), Expect = 0.003
Identities = 43/187 (22%), Positives = 79/187 (42%), Gaps = 10/187 (5%)
Query: 1079 VDSGIVLHSATGPSA-SIDVTLNMKYAVLSDG-DNSVRIWSLAGGDNSEDNRRSVS-HAE 1135
V S + LHSA+ P ++D+ + +L+ G D +V ++ +SE ++ H +
Sbjct: 210 VASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVFD----KSSEQILATLKGHTK 265
Query: 1136 RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSG 1195
++T V + S D ++++W + QV+ H VT +++ T ++S
Sbjct: 266 KVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGD-YLLSS 324
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLA 1253
S D DI T +TC + DG I + D + IW+ K
Sbjct: 325 SDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTN 384
Query: 1254 LTSFSLH 1260
+ +F H
Sbjct: 385 VANFPGH 391
Score = 38.7 bits (86), Expect = 0.15
Identities = 38/210 (18%), Positives = 87/210 (41%), Gaps = 11/210 (5%)
Query: 1049 HSSAIQTLLMM----SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
HS++I +L + SD + ++ +NV V+ S +L + G + + + +
Sbjct: 217 HSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQ 276
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
+ D ++RIWS+ + R +H +T +L A ++++ S D
Sbjct: 277 DLVFSASPDATIRIWSVPNASCVQVVR---AHESAVTGLSLHATGDYLLSSSDDQYWAFS 333
Query: 1162 KLDGGK-LSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
+ G+ L++V S A + +G+ D + +WD+
Sbjct: 334 DIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSG 393
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
+T + + +G + A+D ++ +W+ ++
Sbjct: 394 PITSIAFSENGYYLATAADDSSVKLWDLRK 423
>BC015920-1|AAH15920.1| 297|Homo sapiens GNB3 protein protein.
Length = 297
Score = 69.3 bits (162), Expect = 9e-11
Identities = 59/255 (23%), Positives = 99/255 (38%), Gaps = 11/255 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + ++ ++ L++S S+D ++VW + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSSDRARNVHVWLVDS--GIV-----LHSATGPSASIDVTLNMKYAVLSDGDN 1111
G ++ + S G V L + TG S L+ V S GD
Sbjct: 106 APSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTG-YLSCCRFLDDNNIVTSSGDT 164
Query: 1112 SVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQV 1171
+ +W + G + V H A++ D ++G+ D S K+W + G Q
Sbjct: 165 TCALWDIETG---QQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQT 221
Query: 1172 LVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDG 1231
GH + + + + +G D N VWD +V+C+ VT DG
Sbjct: 222 FTGHESDINAICFFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADG 281
Query: 1232 TIAVSCAEDKTLIIW 1246
+ + D L IW
Sbjct: 282 MAVATGSWDSFLKIW 296
Score = 54.8 bits (126), Expect = 2e-06
Identities = 52/239 (21%), Positives = 94/239 (39%), Gaps = 15/239 (6%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
A + LV A G +W + +KVH S ++ ++ G D +
Sbjct: 64 ATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSI 123
Query: 721 WDLHT----LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
++L + + V ++ H + C + + ++V S GD + + + G T
Sbjct: 124 YNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCAL-WDIETGQQKTVFVG 182
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
H G S+ V D N+FI+G+ D + W+V T T T H D+ F L+
Sbjct: 183 HTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTG----HESDINAICFFSLS 238
Query: 837 ----LQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
G ++ + + + + L H +V C V D VA G D + +++
Sbjct: 239 GRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 297
Score = 53.6 bits (123), Expect = 5e-06
Identities = 54/247 (21%), Positives = 98/247 (39%), Gaps = 11/247 (4%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + + D +L S G + VW +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNFVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMS---DGRRAMSSDRARNVHVWLVDS 1081
G D ++ L ++ SA L D ++S +W +++
Sbjct: 114 CGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIET 173
Query: 1082 G---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERIT 1138
G V TG S+ V+ + + D S ++W + G + S I
Sbjct: 174 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAIC 233
Query: 1139 CFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWD 1198
F+L+ + + G D + VW + +L GH + V+C+ V+ V +GSWD
Sbjct: 234 FFSLSG--RLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMA-VATGSWD 290
Query: 1199 CNLIVWD 1205
L +W+
Sbjct: 291 SFLKIWN 297
Score = 51.2 bits (117), Expect = 3e-05
Identities = 50/194 (25%), Positives = 80/194 (41%), Gaps = 8/194 (4%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +IVWD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D NI +T S D T
Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG--DNELHLRTFITGTYLHPLKRHKA 862
W++E TV G + F L + G D L GT H++
Sbjct: 169 WDIET-GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 863 KVKCFCVAHDSSRV 876
+ C S R+
Sbjct: 228 DINAICFFSLSGRL 241
Score = 33.9 bits (74), Expect = 4.3
Identities = 25/103 (24%), Positives = 41/103 (39%), Gaps = 3/103 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMC-VTRESQYLLTGSEDT 716
L ++P + +LW + + TF GH I +C + + L G +D
Sbjct: 190 LAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFSLSGRLLFAGYDDF 249
Query: 717 SVIVWDLHTLAVKTKILE-HIAPVLCVAAIVNRSLVISGGDDS 758
+ VWD + + IL H V C+ + V +G DS
Sbjct: 250 NCNVWD-SMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDS 291
>AJ243048-1|CAB55588.1| 1248|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1248
Score = 69.3 bits (162), Expect = 9e-11
Identities = 78/382 (20%), Positives = 148/382 (38%), Gaps = 21/382 (5%)
Query: 828 TDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRV--AVGCADQRI 885
TDD F+ T D ++ + +TG +H H +V C + S + A G +D +
Sbjct: 667 TDDR-FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFL 725
Query: 886 YLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQM 945
L+ L+ + T LLA S + L + T
Sbjct: 726 KLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLA---------SCSADGTLKLWDATSAN 776
Query: 946 KRRQTKSTTNITLLQAEQSDL-IPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATL 1004
+R+ L+ Q D+ + + C S DG A+ + ++ + T L +
Sbjct: 777 ERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGAR-IMVAAKNKIFLFDIHTSGLLGEI 835
Query: 1005 N-GHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR 1063
+ GH I FSP N L + V +W S +GH S + ++ DG
Sbjct: 836 HTGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGS 895
Query: 1064 RAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDN 1123
++S + + +W + +SA +DV ++ D+ R+ + G
Sbjct: 896 SFLTSSDDQTIRLWETKK-VCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTG 954
Query: 1124 SEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVA 1183
D ++ A+ ++C L+ Q++ G + ++++ +L ++ Q H V +
Sbjct: 955 QID---YLTEAQ-VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQ 1010
Query: 1184 VSITNKTQVVSGSWDCNLIVWD 1205
+ KT ++S S D + VW+
Sbjct: 1011 FTADEKT-LISSSDDAEIQVWN 1031
Score = 63.7 bits (148), Expect = 5e-09
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 1/147 (0%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKT 1190
+H + + C A + D + + T S+D +K+W G+L HS+ V C + ++
Sbjct: 655 AHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHL 714
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
+ +GS DC L +WD+N V + + D + SC+ D TL +W+
Sbjct: 715 LLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATS 774
Query: 1251 GLALTSFSLHVPLLGFQITSDCARVVV 1277
S ++ L + + V+V
Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIV 801
Score = 62.9 bits (146), Expect = 8e-09
Identities = 66/316 (20%), Positives = 126/316 (39%), Gaps = 23/316 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I + S L ++ V +W + A GH+ + V FSP+ L+ S+
Sbjct: 843 IQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSD 902
Query: 1029 DRTVVVWQ---LADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W+ + NS + + Q +M ++ D R + + +G +
Sbjct: 903 DQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVM-----VLAVDHIRRLQLINGRTGQID 957
Query: 1086 HSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
+ + ++ +++Y D + ++ I L N+ + H + + TAD
Sbjct: 958 YLTEAQVSCCCLSPHLQYIAFGDENGAIEILELV---NNRIFQSRFQHKKTVWHIQFTAD 1014
Query: 1146 SQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ +++ S D ++VW K L GH + T + ++++S S+D + VW+
Sbjct: 1015 EKTLISSSDDAEIQVWNWQLDKCI-FLRGHQE--TVKDFRLLKNSRLLSWSFDGTVKVWN 1071
Query: 1206 INTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLG 1265
I T V ++ D T S + DKT IW SF L +PL
Sbjct: 1072 IITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIW---------SFDLLLPLHE 1122
Query: 1266 FQITSDCARVVVHLLD 1281
+ + C R +D
Sbjct: 1123 LRGHNGCVRCSAFSVD 1138
Score = 57.2 bits (132), Expect = 4e-07
Identities = 60/318 (18%), Positives = 129/318 (40%), Gaps = 23/318 (7%)
Query: 951 KSTTNIT-LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIG 1009
K+ TN++ L+ +D + +C S DGQ AS A ++V++ T + H
Sbjct: 601 KNITNLSRLVVRPHTDAVYHACF--SEDGQRIASCGADKTLQVFKAETGEKLLEIKAHED 658
Query: 1010 HITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSD 1069
+ C FS ++ + + S D+ V +W TY HS + + + +
Sbjct: 659 EVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLAT 718
Query: 1070 RARN--VHVWLVDSGIVLHSATGPSASID---VTLNMKYAVLSDGDNSVRIWSLAGGD-- 1122
+ + + +W ++ ++ G + S++ + + K D ++++W +
Sbjct: 719 GSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANER 778
Query: 1123 ----------NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
N ED + + + C + +AD ++ + + G L ++
Sbjct: 779 KSINVKQFFLNLEDPQEDMEVI--VKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIH 836
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGT 1232
GH + S N VV+ S C + +W+ ++ V V + DG+
Sbjct: 837 TGHHSTIQYCDFSPQNHLAVVALSQYC-VELWNTDSRSKVADCRGHLSWVHGVMFSPDGS 895
Query: 1233 IAVSCAEDKTLIIWETKR 1250
++ ++D+T+ +WETK+
Sbjct: 896 SFLTSSDDQTIRLWETKK 913
Score = 53.6 bits (123), Expect = 5e-06
Identities = 42/202 (20%), Positives = 91/202 (45%), Gaps = 5/202 (2%)
Query: 697 ILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGD 756
+ C C++ QY+ G E+ ++ + +L + +H V + + +IS D
Sbjct: 964 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 1023
Query: 757 DSAVIITSL-VDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLST 815
D+ + + + +D + L H+ +V +++++ + ++ S DGTV WN+
Sbjct: 1024 DAEIQVWNWQLDKCIF--LRGHQETVKDFRLLKNSRL-LSWSFDGTVKVWNIITGNKEKD 1080
Query: 816 -VTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSS 874
V + D++ D + D + +F LH L+ H V+C + DS+
Sbjct: 1081 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST 1140
Query: 875 RVAVGCADQRIYLYSLHSAQLL 896
+A G + I ++++ + +LL
Sbjct: 1141 LLATGDDNGEIRIWNVSNGELL 1162
Score = 52.0 bits (119), Expect = 2e-05
Identities = 44/205 (21%), Positives = 86/205 (41%), Gaps = 12/205 (5%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC +S Q A G G + + +L +R+ + H + + F+ + ++S S+
Sbjct: 964 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 1023
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSG-----I 1083
D + VW + + +GH ++ ++ + R +S V VW + +G
Sbjct: 1024 DAEIQVWNWQLDK-CIFLRGHQETVKDFRLLKNSR-LLSWSFDGTVKVWNIITGNKEKDF 1081
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
V H T S D++ + + D + +IWS D H + C A +
Sbjct: 1082 VCHQGT--VLSCDISHDATKFSSTSADKTAKIWSF---DLLLPLHELRGHNGCVRCSAFS 1136
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKL 1168
DS + TG + +++W + G+L
Sbjct: 1137 VDSTLLATGDDNGEIRIWNVSNGEL 1161
Score = 49.6 bits (113), Expect = 8e-05
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 10/142 (7%)
Query: 674 GDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKIL 733
G ++W+I++ +K F H G++L ++ ++ + S D + +W L ++
Sbjct: 1065 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1124
Query: 734 EHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALV---TKLDH-----HRGSVTSVK 785
H V C A V+ +L+ +G D+ + I ++ +G L+ L H G VT +
Sbjct: 1125 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1184
Query: 786 VIQDGNIFITGSQDGTVCTWNV 807
DG + I S G + WNV
Sbjct: 1185 FSPDGKMLI--SAGGYIKWWNV 1204
Score = 44.0 bits (99), Expect = 0.004
Identities = 33/146 (22%), Positives = 58/146 (39%), Gaps = 4/146 (2%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
GQ + + Q++ + K+ K H +LC + + +++ T S D V +W+
Sbjct: 627 GQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNS 686
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRS---LVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
T + EH V C N S L+ +G D + + L + H S
Sbjct: 687 MTGELVHTYDEHSEQVNC-CHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNS 745
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWN 806
V + D + + S DGT+ W+
Sbjct: 746 VNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 42.3 bits (95), Expect = 0.012
Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 9/147 (6%)
Query: 988 GLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYK 1047
G V+VW + T + H G + S + S S D+T +W P +
Sbjct: 1065 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1124
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH---------SATGPSASIDVT 1098
GH+ ++ D + D + +W V +G +LH +AT D+
Sbjct: 1125 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1184
Query: 1099 LNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+ +L ++ W++ G++S+
Sbjct: 1185 FSPDGKMLISAGGYIKWWNVVTGESSQ 1211
Score = 41.5 bits (93), Expect = 0.021
Identities = 51/261 (19%), Positives = 100/261 (38%), Gaps = 19/261 (7%)
Query: 918 LAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRD 977
+ A + V +F T+D + + T + E S+ + S
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSH 712
Query: 978 GQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL 1037
L A+G + +++W L+ + T+ GH + FSP++ L+ S S D T+ +W
Sbjct: 713 HLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDA 772
Query: 1038 --ADNSPSLTYK-----------GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIV 1084
A+ S+ K ++ +DG R M + + + + SG++
Sbjct: 773 TSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLL 832
Query: 1085 LHSATGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFA 1141
TG ++I D + AV++ V +W+ D R H +
Sbjct: 833 GEIHTGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCR---GHLSWVHGVM 889
Query: 1142 LTADSQHVVTGSMDMSLKVWK 1162
+ D +T S D ++++W+
Sbjct: 890 FSPDGSSFLTSSDDQTIRLWE 910
Score = 41.1 bits (92), Expect = 0.028
Identities = 40/199 (20%), Positives = 79/199 (39%), Gaps = 7/199 (3%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
L+P Q++ G ++ +++N + H ++ + T + + L++ S+D +
Sbjct: 969 LSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQ 1028
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
VW+ K L + ++ S ++S D V + +++ G H+G
Sbjct: 1029 VWNWQ--LDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1086
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV---TAGVPIHIFDVTDDNVFLLT 836
+V S + D F + S D T W+ + L + V F V D+ L T
Sbjct: 1087 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSV--DSTLLAT 1144
Query: 837 LQGDNELHLRTFITGTYLH 855
+ E+ + G LH
Sbjct: 1145 GDDNGEIRIWNVSNGELLH 1163
Score = 40.3 bits (90), Expect = 0.050
Identities = 46/220 (20%), Positives = 88/220 (40%), Gaps = 17/220 (7%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ ++ C + + Q + + D ++ V+ T +I H VLC A + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN--IFITGSQDGTVCTWNVENF 810
+ D V I + + G LV D H V + + TGS D + W++
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 811 TLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGT----------YLH---P 856
+T+ ++ + D+ L + D L L + +L+ P
Sbjct: 734 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDP 793
Query: 857 LKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
+ + VKC + D +R+ V A +I+L+ +H++ LL
Sbjct: 794 QEDMEVIVKCCSWSADGARIMV-AAKNKIFLFDIHTSGLL 832
Score = 33.5 bits (73), Expect = 5.7
Identities = 17/73 (23%), Positives = 35/73 (47%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+P V+A S +LW+ S SKV +GH + + + + LT S+D ++ +
Sbjct: 849 SPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRL 908
Query: 721 WDLHTLAVKTKIL 733
W+ + + ++
Sbjct: 909 WETKKVCKNSAVM 921
>AF149794-1|AAD34016.1| 1248|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1248
Score = 69.3 bits (162), Expect = 9e-11
Identities = 78/382 (20%), Positives = 148/382 (38%), Gaps = 21/382 (5%)
Query: 828 TDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRV--AVGCADQRI 885
TDD F+ T D ++ + +TG +H H +V C + S + A G +D +
Sbjct: 667 TDDR-FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFL 725
Query: 886 YLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQM 945
L+ L+ + T LLA S + L + T
Sbjct: 726 KLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLA---------SCSADGTLKLWDATSAN 776
Query: 946 KRRQTKSTTNITLLQAEQSDL-IPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATL 1004
+R+ L+ Q D+ + + C S DG A+ + ++ + T L +
Sbjct: 777 ERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGAR-IMVAAKNKIFLFDIHTSGLLGEI 835
Query: 1005 N-GHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR 1063
+ GH I FSP N L + V +W S +GH S + ++ DG
Sbjct: 836 HTGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGS 895
Query: 1064 RAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDN 1123
++S + + +W + +SA +DV ++ D+ R+ + G
Sbjct: 896 SFLTSSDDQTIRLWETKK-VCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTG 954
Query: 1124 SEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVA 1183
D ++ A+ ++C L+ Q++ G + ++++ +L ++ Q H V +
Sbjct: 955 QID---YLTEAQ-VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQ 1010
Query: 1184 VSITNKTQVVSGSWDCNLIVWD 1205
+ KT ++S S D + VW+
Sbjct: 1011 FTADEKT-LISSSDDAEIQVWN 1031
Score = 63.7 bits (148), Expect = 5e-09
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 1/147 (0%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKT 1190
+H + + C A + D + + T S+D +K+W G+L HS+ V C + ++
Sbjct: 655 AHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHL 714
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
+ +GS DC L +WD+N V + + D + SC+ D TL +W+
Sbjct: 715 LLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATS 774
Query: 1251 GLALTSFSLHVPLLGFQITSDCARVVV 1277
S ++ L + + V+V
Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIV 801
Score = 62.9 bits (146), Expect = 8e-09
Identities = 66/316 (20%), Positives = 126/316 (39%), Gaps = 23/316 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I + S L ++ V +W + A GH+ + V FSP+ L+ S+
Sbjct: 843 IQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSD 902
Query: 1029 DRTVVVWQ---LADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W+ + NS + + Q +M ++ D R + + +G +
Sbjct: 903 DQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVM-----VLAVDHIRRLQLINGRTGQID 957
Query: 1086 HSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
+ + ++ +++Y D + ++ I L N+ + H + + TAD
Sbjct: 958 YLTEAQVSCCCLSPHLQYIAFGDENGAIEILELV---NNRIFQSRFQHKKTVWHIQFTAD 1014
Query: 1146 SQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ +++ S D ++VW K L GH + T + ++++S S+D + VW+
Sbjct: 1015 EKTLISSSDDAEIQVWNWQLDKCI-FLRGHQE--TVKDFRLLKNSRLLSWSFDGTVKVWN 1071
Query: 1206 INTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLG 1265
I T V ++ D T S + DKT IW SF L +PL
Sbjct: 1072 IITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIW---------SFDLLLPLHE 1122
Query: 1266 FQITSDCARVVVHLLD 1281
+ + C R +D
Sbjct: 1123 LRGHNGCVRCSAFSVD 1138
Score = 57.2 bits (132), Expect = 4e-07
Identities = 60/318 (18%), Positives = 129/318 (40%), Gaps = 23/318 (7%)
Query: 951 KSTTNIT-LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIG 1009
K+ TN++ L+ +D + +C S DGQ AS A ++V++ T + H
Sbjct: 601 KNITNLSRLVVRPHTDAVYHACF--SEDGQRIASCGADKTLQVFKAETGEKLLEIKAHED 658
Query: 1010 HITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSD 1069
+ C FS ++ + + S D+ V +W TY HS + + + +
Sbjct: 659 EVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLAT 718
Query: 1070 RARN--VHVWLVDSGIVLHSATGPSASID---VTLNMKYAVLSDGDNSVRIWSLAGGD-- 1122
+ + + +W ++ ++ G + S++ + + K D ++++W +
Sbjct: 719 GSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANER 778
Query: 1123 ----------NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
N ED + + + C + +AD ++ + + G L ++
Sbjct: 779 KSINVKQFFLNLEDPQEDMEVI--VKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIH 836
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGT 1232
GH + S N VV+ S C + +W+ ++ V V + DG+
Sbjct: 837 TGHHSTIQYCDFSPQNHLAVVALSQYC-VELWNTDSRSKVADCRGHLSWVHGVMFSPDGS 895
Query: 1233 IAVSCAEDKTLIIWETKR 1250
++ ++D+T+ +WETK+
Sbjct: 896 SFLTSSDDQTIRLWETKK 913
Score = 53.6 bits (123), Expect = 5e-06
Identities = 42/202 (20%), Positives = 91/202 (45%), Gaps = 5/202 (2%)
Query: 697 ILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGD 756
+ C C++ QY+ G E+ ++ + +L + +H V + + +IS D
Sbjct: 964 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 1023
Query: 757 DSAVIITSL-VDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLST 815
D+ + + + +D + L H+ +V +++++ + ++ S DGTV WN+
Sbjct: 1024 DAEIQVWNWQLDKCIF--LRGHQETVKDFRLLKNSRL-LSWSFDGTVKVWNIITGNKEKD 1080
Query: 816 -VTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSS 874
V + D++ D + D + +F LH L+ H V+C + DS+
Sbjct: 1081 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST 1140
Query: 875 RVAVGCADQRIYLYSLHSAQLL 896
+A G + I ++++ + +LL
Sbjct: 1141 LLATGDDNGEIRIWNVSNGELL 1162
Score = 52.0 bits (119), Expect = 2e-05
Identities = 44/205 (21%), Positives = 86/205 (41%), Gaps = 12/205 (5%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC +S Q A G G + + +L +R+ + H + + F+ + ++S S+
Sbjct: 964 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 1023
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSG-----I 1083
D + VW + + +GH ++ ++ + R +S V VW + +G
Sbjct: 1024 DAEIQVWNWQLDK-CIFLRGHQETVKDFRLLKNSR-LLSWSFDGTVKVWNIITGNKEKDF 1081
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
V H T S D++ + + D + +IWS D H + C A +
Sbjct: 1082 VCHQGT--VLSCDISHDATKFSSTSADKTAKIWSF---DLLLPLHELRGHNGCVRCSAFS 1136
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKL 1168
DS + TG + +++W + G+L
Sbjct: 1137 VDSTLLATGDDNGEIRIWNVSNGEL 1161
Score = 49.6 bits (113), Expect = 8e-05
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 10/142 (7%)
Query: 674 GDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKIL 733
G ++W+I++ +K F H G++L ++ ++ + S D + +W L ++
Sbjct: 1065 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1124
Query: 734 EHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALV---TKLDH-----HRGSVTSVK 785
H V C A V+ +L+ +G D+ + I ++ +G L+ L H G VT +
Sbjct: 1125 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1184
Query: 786 VIQDGNIFITGSQDGTVCTWNV 807
DG + I S G + WNV
Sbjct: 1185 FSPDGKMLI--SAGGYIKWWNV 1204
Score = 44.0 bits (99), Expect = 0.004
Identities = 33/146 (22%), Positives = 58/146 (39%), Gaps = 4/146 (2%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
GQ + + Q++ + K+ K H +LC + + +++ T S D V +W+
Sbjct: 627 GQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNS 686
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRS---LVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
T + EH V C N S L+ +G D + + L + H S
Sbjct: 687 MTGELVHTYDEHSEQVNC-CHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNS 745
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWN 806
V + D + + S DGT+ W+
Sbjct: 746 VNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 42.3 bits (95), Expect = 0.012
Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 9/147 (6%)
Query: 988 GLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYK 1047
G V+VW + T + H G + S + S S D+T +W P +
Sbjct: 1065 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1124
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH---------SATGPSASIDVT 1098
GH+ ++ D + D + +W V +G +LH +AT D+
Sbjct: 1125 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1184
Query: 1099 LNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+ +L ++ W++ G++S+
Sbjct: 1185 FSPDGKMLISAGGYIKWWNVVTGESSQ 1211
Score = 41.5 bits (93), Expect = 0.021
Identities = 51/261 (19%), Positives = 100/261 (38%), Gaps = 19/261 (7%)
Query: 918 LAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRD 977
+ A + V +F T+D + + T + E S+ + S
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSH 712
Query: 978 GQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL 1037
L A+G + +++W L+ + T+ GH + FSP++ L+ S S D T+ +W
Sbjct: 713 HLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDA 772
Query: 1038 --ADNSPSLTYK-----------GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIV 1084
A+ S+ K ++ +DG R M + + + + SG++
Sbjct: 773 TSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLL 832
Query: 1085 LHSATGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFA 1141
TG ++I D + AV++ V +W+ D R H +
Sbjct: 833 GEIHTGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCR---GHLSWVHGVM 889
Query: 1142 LTADSQHVVTGSMDMSLKVWK 1162
+ D +T S D ++++W+
Sbjct: 890 FSPDGSSFLTSSDDQTIRLWE 910
Score = 41.1 bits (92), Expect = 0.028
Identities = 40/199 (20%), Positives = 79/199 (39%), Gaps = 7/199 (3%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
L+P Q++ G ++ +++N + H ++ + T + + L++ S+D +
Sbjct: 969 LSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQ 1028
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
VW+ K L + ++ S ++S D V + +++ G H+G
Sbjct: 1029 VWNWQ--LDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1086
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV---TAGVPIHIFDVTDDNVFLLT 836
+V S + D F + S D T W+ + L + V F V D+ L T
Sbjct: 1087 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSV--DSTLLAT 1144
Query: 837 LQGDNELHLRTFITGTYLH 855
+ E+ + G LH
Sbjct: 1145 GDDNGEIRIWNVSNGELLH 1163
Score = 40.3 bits (90), Expect = 0.050
Identities = 46/220 (20%), Positives = 88/220 (40%), Gaps = 17/220 (7%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ ++ C + + Q + + D ++ V+ T +I H VLC A + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN--IFITGSQDGTVCTWNVENF 810
+ D V I + + G LV D H V + + TGS D + W++
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 811 TLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGT----------YLH---P 856
+T+ ++ + D+ L + D L L + +L+ P
Sbjct: 734 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDP 793
Query: 857 LKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
+ + VKC + D +R+ V A +I+L+ +H++ LL
Sbjct: 794 QEDMEVIVKCCSWSADGARIMV-AAKNKIFLFDIHTSGLL 832
Score = 33.5 bits (73), Expect = 5.7
Identities = 17/73 (23%), Positives = 35/73 (47%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+P V+A S +LW+ S SKV +GH + + + + LT S+D ++ +
Sbjct: 849 SPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRL 908
Query: 721 WDLHTLAVKTKIL 733
W+ + + ++
Sbjct: 909 WETKKVCKNSAVM 921
>AF134397-1|AAD38344.1| 1237|Homo sapiens apoptotic protease
activating factor-1 long isoform APAF-1L protein.
Length = 1237
Score = 69.3 bits (162), Expect = 9e-11
Identities = 78/382 (20%), Positives = 148/382 (38%), Gaps = 21/382 (5%)
Query: 828 TDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRV--AVGCADQRI 885
TDD F+ T D ++ + +TG +H H +V C + S + A G +D +
Sbjct: 656 TDDR-FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFL 714
Query: 886 YLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQM 945
L+ L+ + T LLA S + L + T
Sbjct: 715 KLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLA---------SCSADGTLKLWDATSAN 765
Query: 946 KRRQTKSTTNITLLQAEQSDL-IPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATL 1004
+R+ L+ Q D+ + + C S DG A+ + ++ + T L +
Sbjct: 766 ERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGAR-IMVAAKNKIFLFDIHTSGLLGEI 824
Query: 1005 N-GHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR 1063
+ GH I FSP N L + V +W S +GH S + ++ DG
Sbjct: 825 HTGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGS 884
Query: 1064 RAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDN 1123
++S + + +W + +SA +DV ++ D+ R+ + G
Sbjct: 885 SFLTSSDDQTIRLWETKK-VCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTG 943
Query: 1124 SEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVA 1183
D ++ A+ ++C L+ Q++ G + ++++ +L ++ Q H V +
Sbjct: 944 QID---YLTEAQ-VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQ 999
Query: 1184 VSITNKTQVVSGSWDCNLIVWD 1205
+ KT ++S S D + VW+
Sbjct: 1000 FTADEKT-LISSSDDAEIQVWN 1020
Score = 63.7 bits (148), Expect = 5e-09
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 1/147 (0%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKT 1190
+H + + C A + D + + T S+D +K+W G+L HS+ V C + ++
Sbjct: 644 AHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHL 703
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
+ +GS DC L +WD+N V + + D + SC+ D TL +W+
Sbjct: 704 LLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATS 763
Query: 1251 GLALTSFSLHVPLLGFQITSDCARVVV 1277
S ++ L + + V+V
Sbjct: 764 ANERKSINVKQFFLNLEDPQEDMEVIV 790
Score = 62.9 bits (146), Expect = 8e-09
Identities = 66/316 (20%), Positives = 126/316 (39%), Gaps = 23/316 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I + S L ++ V +W + A GH+ + V FSP+ L+ S+
Sbjct: 832 IQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSD 891
Query: 1029 DRTVVVWQ---LADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W+ + NS + + Q +M ++ D R + + +G +
Sbjct: 892 DQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVM-----VLAVDHIRRLQLINGRTGQID 946
Query: 1086 HSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
+ + ++ +++Y D + ++ I L N+ + H + + TAD
Sbjct: 947 YLTEAQVSCCCLSPHLQYIAFGDENGAIEILELV---NNRIFQSRFQHKKTVWHIQFTAD 1003
Query: 1146 SQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ +++ S D ++VW K L GH + T + ++++S S+D + VW+
Sbjct: 1004 EKTLISSSDDAEIQVWNWQLDKCI-FLRGHQE--TVKDFRLLKNSRLLSWSFDGTVKVWN 1060
Query: 1206 INTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLG 1265
I T V ++ D T S + DKT IW SF L +PL
Sbjct: 1061 IITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIW---------SFDLLLPLHE 1111
Query: 1266 FQITSDCARVVVHLLD 1281
+ + C R +D
Sbjct: 1112 LRGHNGCVRCSAFSVD 1127
Score = 57.2 bits (132), Expect = 4e-07
Identities = 60/318 (18%), Positives = 129/318 (40%), Gaps = 23/318 (7%)
Query: 951 KSTTNIT-LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIG 1009
K+ TN++ L+ +D + +C S DGQ AS A ++V++ T + H
Sbjct: 590 KNITNLSRLVVRPHTDAVYHACF--SEDGQRIASCGADKTLQVFKAETGEKLLEIKAHED 647
Query: 1010 HITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSD 1069
+ C FS ++ + + S D+ V +W TY HS + + + +
Sbjct: 648 EVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLAT 707
Query: 1070 RARN--VHVWLVDSGIVLHSATGPSASID---VTLNMKYAVLSDGDNSVRIWSLAGGD-- 1122
+ + + +W ++ ++ G + S++ + + K D ++++W +
Sbjct: 708 GSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANER 767
Query: 1123 ----------NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
N ED + + + C + +AD ++ + + G L ++
Sbjct: 768 KSINVKQFFLNLEDPQEDMEVI--VKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIH 825
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGT 1232
GH + S N VV+ S C + +W+ ++ V V + DG+
Sbjct: 826 TGHHSTIQYCDFSPQNHLAVVALSQYC-VELWNTDSRSKVADCRGHLSWVHGVMFSPDGS 884
Query: 1233 IAVSCAEDKTLIIWETKR 1250
++ ++D+T+ +WETK+
Sbjct: 885 SFLTSSDDQTIRLWETKK 902
Score = 53.6 bits (123), Expect = 5e-06
Identities = 42/202 (20%), Positives = 91/202 (45%), Gaps = 5/202 (2%)
Query: 697 ILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGD 756
+ C C++ QY+ G E+ ++ + +L + +H V + + +IS D
Sbjct: 953 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 1012
Query: 757 DSAVIITSL-VDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLST 815
D+ + + + +D + L H+ +V +++++ + ++ S DGTV WN+
Sbjct: 1013 DAEIQVWNWQLDKCIF--LRGHQETVKDFRLLKNSRL-LSWSFDGTVKVWNIITGNKEKD 1069
Query: 816 -VTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSS 874
V + D++ D + D + +F LH L+ H V+C + DS+
Sbjct: 1070 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST 1129
Query: 875 RVAVGCADQRIYLYSLHSAQLL 896
+A G + I ++++ + +LL
Sbjct: 1130 LLATGDDNGEIRIWNVSNGELL 1151
Score = 52.0 bits (119), Expect = 2e-05
Identities = 44/205 (21%), Positives = 86/205 (41%), Gaps = 12/205 (5%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC +S Q A G G + + +L +R+ + H + + F+ + ++S S+
Sbjct: 953 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 1012
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSG-----I 1083
D + VW + + +GH ++ ++ + R +S V VW + +G
Sbjct: 1013 DAEIQVWNWQLDK-CIFLRGHQETVKDFRLLKNSR-LLSWSFDGTVKVWNIITGNKEKDF 1070
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
V H T S D++ + + D + +IWS D H + C A +
Sbjct: 1071 VCHQGT--VLSCDISHDATKFSSTSADKTAKIWSF---DLLLPLHELRGHNGCVRCSAFS 1125
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKL 1168
DS + TG + +++W + G+L
Sbjct: 1126 VDSTLLATGDDNGEIRIWNVSNGEL 1150
Score = 49.6 bits (113), Expect = 8e-05
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 10/142 (7%)
Query: 674 GDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKIL 733
G ++W+I++ +K F H G++L ++ ++ + S D + +W L ++
Sbjct: 1054 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1113
Query: 734 EHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALV---TKLDH-----HRGSVTSVK 785
H V C A V+ +L+ +G D+ + I ++ +G L+ L H G VT +
Sbjct: 1114 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1173
Query: 786 VIQDGNIFITGSQDGTVCTWNV 807
DG + I S G + WNV
Sbjct: 1174 FSPDGKMLI--SAGGYIKWWNV 1193
Score = 44.0 bits (99), Expect = 0.004
Identities = 33/146 (22%), Positives = 58/146 (39%), Gaps = 4/146 (2%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
GQ + + Q++ + K+ K H +LC + + +++ T S D V +W+
Sbjct: 616 GQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNS 675
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRS---LVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
T + EH V C N S L+ +G D + + L + H S
Sbjct: 676 MTGELVHTYDEHSEQVNC-CHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNS 734
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWN 806
V + D + + S DGT+ W+
Sbjct: 735 VNHCRFSPDDKLLASCSADGTLKLWD 760
Score = 42.3 bits (95), Expect = 0.012
Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 9/147 (6%)
Query: 988 GLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYK 1047
G V+VW + T + H G + S + S S D+T +W P +
Sbjct: 1054 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1113
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH---------SATGPSASIDVT 1098
GH+ ++ D + D + +W V +G +LH +AT D+
Sbjct: 1114 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1173
Query: 1099 LNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+ +L ++ W++ G++S+
Sbjct: 1174 FSPDGKMLISAGGYIKWWNVVTGESSQ 1200
Score = 41.5 bits (93), Expect = 0.021
Identities = 51/261 (19%), Positives = 100/261 (38%), Gaps = 19/261 (7%)
Query: 918 LAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRD 977
+ A + V +F T+D + + T + E S+ + S
Sbjct: 642 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSH 701
Query: 978 GQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL 1037
L A+G + +++W L+ + T+ GH + FSP++ L+ S S D T+ +W
Sbjct: 702 HLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDA 761
Query: 1038 --ADNSPSLTYK-----------GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIV 1084
A+ S+ K ++ +DG R M + + + + SG++
Sbjct: 762 TSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLL 821
Query: 1085 LHSATGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFA 1141
TG ++I D + AV++ V +W+ D R H +
Sbjct: 822 GEIHTGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCR---GHLSWVHGVM 878
Query: 1142 LTADSQHVVTGSMDMSLKVWK 1162
+ D +T S D ++++W+
Sbjct: 879 FSPDGSSFLTSSDDQTIRLWE 899
Score = 41.1 bits (92), Expect = 0.028
Identities = 40/199 (20%), Positives = 79/199 (39%), Gaps = 7/199 (3%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
L+P Q++ G ++ +++N + H ++ + T + + L++ S+D +
Sbjct: 958 LSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQ 1017
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
VW+ K L + ++ S ++S D V + +++ G H+G
Sbjct: 1018 VWNWQ--LDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1075
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV---TAGVPIHIFDVTDDNVFLLT 836
+V S + D F + S D T W+ + L + V F V D+ L T
Sbjct: 1076 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSV--DSTLLAT 1133
Query: 837 LQGDNELHLRTFITGTYLH 855
+ E+ + G LH
Sbjct: 1134 GDDNGEIRIWNVSNGELLH 1152
Score = 40.3 bits (90), Expect = 0.050
Identities = 46/220 (20%), Positives = 88/220 (40%), Gaps = 17/220 (7%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ ++ C + + Q + + D ++ V+ T +I H VLC A + +
Sbjct: 603 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 662
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN--IFITGSQDGTVCTWNVENF 810
+ D V I + + G LV D H V + + TGS D + W++
Sbjct: 663 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 722
Query: 811 TLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGT----------YLH---P 856
+T+ ++ + D+ L + D L L + +L+ P
Sbjct: 723 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDP 782
Query: 857 LKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
+ + VKC + D +R+ V A +I+L+ +H++ LL
Sbjct: 783 QEDMEVIVKCCSWSADGARIMV-AAKNKIFLFDIHTSGLL 821
Score = 33.5 bits (73), Expect = 5.7
Identities = 17/73 (23%), Positives = 35/73 (47%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+P V+A S +LW+ S SKV +GH + + + + LT S+D ++ +
Sbjct: 838 SPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRL 897
Query: 721 WDLHTLAVKTKIL 733
W+ + + ++
Sbjct: 898 WETKKVCKNSAVM 910
>AB007873-1|BAA24843.2| 1237|Homo sapiens KIAA0413 protein.
Length = 1237
Score = 69.3 bits (162), Expect = 9e-11
Identities = 78/382 (20%), Positives = 148/382 (38%), Gaps = 21/382 (5%)
Query: 828 TDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRV--AVGCADQRI 885
TDD F+ T D ++ + +TG +H H +V C + S + A G +D +
Sbjct: 656 TDDR-FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFL 714
Query: 886 YLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQM 945
L+ L+ + T LLA S + L + T
Sbjct: 715 KLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLA---------SCSADGTLKLWDATSAN 765
Query: 946 KRRQTKSTTNITLLQAEQSDL-IPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATL 1004
+R+ L+ Q D+ + + C S DG A+ + ++ + T L +
Sbjct: 766 ERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGAR-IMVAAKNKIFLFDIHTSGLLGEI 824
Query: 1005 N-GHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR 1063
+ GH I FSP N L + V +W S +GH S + ++ DG
Sbjct: 825 HTGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGS 884
Query: 1064 RAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDN 1123
++S + + +W + +SA +DV ++ D+ R+ + G
Sbjct: 885 SFLTSSDDQTIRLWETKK-VCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTG 943
Query: 1124 SEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVA 1183
D ++ A+ ++C L+ Q++ G + ++++ +L ++ Q H V +
Sbjct: 944 QID---YLTEAQ-VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQ 999
Query: 1184 VSITNKTQVVSGSWDCNLIVWD 1205
+ KT ++S S D + VW+
Sbjct: 1000 FTADEKT-LISSSDDAEIQVWN 1020
Score = 63.7 bits (148), Expect = 5e-09
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 1/147 (0%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKT 1190
+H + + C A + D + + T S+D +K+W G+L HS+ V C + ++
Sbjct: 644 AHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHL 703
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
+ +GS DC L +WD+N V + + D + SC+ D TL +W+
Sbjct: 704 LLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATS 763
Query: 1251 GLALTSFSLHVPLLGFQITSDCARVVV 1277
S ++ L + + V+V
Sbjct: 764 ANERKSINVKQFFLNLEDPQEDMEVIV 790
Score = 62.9 bits (146), Expect = 8e-09
Identities = 66/316 (20%), Positives = 126/316 (39%), Gaps = 23/316 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I + S L ++ V +W + A GH+ + V FSP+ L+ S+
Sbjct: 832 IQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSD 891
Query: 1029 DRTVVVWQ---LADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W+ + NS + + Q +M ++ D R + + +G +
Sbjct: 892 DQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVM-----VLAVDHIRRLQLINGRTGQID 946
Query: 1086 HSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
+ + ++ +++Y D + ++ I L N+ + H + + TAD
Sbjct: 947 YLTEAQVSCCCLSPHLQYIAFGDENGAIEILELV---NNRIFQSRFQHKKTVWHIQFTAD 1003
Query: 1146 SQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ +++ S D ++VW K L GH + T + ++++S S+D + VW+
Sbjct: 1004 EKTLISSSDDAEIQVWNWQLDKCI-FLRGHQE--TVKDFRLLKNSRLLSWSFDGTVKVWN 1060
Query: 1206 INTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLG 1265
I T V ++ D T S + DKT IW SF L +PL
Sbjct: 1061 IITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIW---------SFDLLLPLHE 1111
Query: 1266 FQITSDCARVVVHLLD 1281
+ + C R +D
Sbjct: 1112 LRGHNGCVRCSAFSVD 1127
Score = 57.2 bits (132), Expect = 4e-07
Identities = 60/318 (18%), Positives = 129/318 (40%), Gaps = 23/318 (7%)
Query: 951 KSTTNIT-LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIG 1009
K+ TN++ L+ +D + +C S DGQ AS A ++V++ T + H
Sbjct: 590 KNITNLSRLVVRPHTDAVYHACF--SEDGQRIASCGADKTLQVFKAETGEKLLEIKAHED 647
Query: 1010 HITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSD 1069
+ C FS ++ + + S D+ V +W TY HS + + + +
Sbjct: 648 EVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLAT 707
Query: 1070 RARN--VHVWLVDSGIVLHSATGPSASID---VTLNMKYAVLSDGDNSVRIWSLAGGD-- 1122
+ + + +W ++ ++ G + S++ + + K D ++++W +
Sbjct: 708 GSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANER 767
Query: 1123 ----------NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
N ED + + + C + +AD ++ + + G L ++
Sbjct: 768 KSINVKQFFLNLEDPQEDMEVI--VKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIH 825
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGT 1232
GH + S N VV+ S C + +W+ ++ V V + DG+
Sbjct: 826 TGHHSTIQYCDFSPQNHLAVVALSQYC-VELWNTDSRSKVADCRGHLSWVHGVMFSPDGS 884
Query: 1233 IAVSCAEDKTLIIWETKR 1250
++ ++D+T+ +WETK+
Sbjct: 885 SFLTSSDDQTIRLWETKK 902
Score = 53.6 bits (123), Expect = 5e-06
Identities = 42/202 (20%), Positives = 91/202 (45%), Gaps = 5/202 (2%)
Query: 697 ILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGD 756
+ C C++ QY+ G E+ ++ + +L + +H V + + +IS D
Sbjct: 953 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 1012
Query: 757 DSAVIITSL-VDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLST 815
D+ + + + +D + L H+ +V +++++ + ++ S DGTV WN+
Sbjct: 1013 DAEIQVWNWQLDKCIF--LRGHQETVKDFRLLKNSRL-LSWSFDGTVKVWNIITGNKEKD 1069
Query: 816 -VTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSS 874
V + D++ D + D + +F LH L+ H V+C + DS+
Sbjct: 1070 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST 1129
Query: 875 RVAVGCADQRIYLYSLHSAQLL 896
+A G + I ++++ + +LL
Sbjct: 1130 LLATGDDNGEIRIWNVSNGELL 1151
Score = 52.0 bits (119), Expect = 2e-05
Identities = 44/205 (21%), Positives = 86/205 (41%), Gaps = 12/205 (5%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC +S Q A G G + + +L +R+ + H + + F+ + ++S S+
Sbjct: 953 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 1012
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSG-----I 1083
D + VW + + +GH ++ ++ + R +S V VW + +G
Sbjct: 1013 DAEIQVWNWQLDK-CIFLRGHQETVKDFRLLKNSR-LLSWSFDGTVKVWNIITGNKEKDF 1070
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
V H T S D++ + + D + +IWS D H + C A +
Sbjct: 1071 VCHQGT--VLSCDISHDATKFSSTSADKTAKIWSF---DLLLPLHELRGHNGCVRCSAFS 1125
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKL 1168
DS + TG + +++W + G+L
Sbjct: 1126 VDSTLLATGDDNGEIRIWNVSNGEL 1150
Score = 49.6 bits (113), Expect = 8e-05
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 10/142 (7%)
Query: 674 GDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKIL 733
G ++W+I++ +K F H G++L ++ ++ + S D + +W L ++
Sbjct: 1054 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1113
Query: 734 EHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALV---TKLDH-----HRGSVTSVK 785
H V C A V+ +L+ +G D+ + I ++ +G L+ L H G VT +
Sbjct: 1114 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1173
Query: 786 VIQDGNIFITGSQDGTVCTWNV 807
DG + I S G + WNV
Sbjct: 1174 FSPDGKMLI--SAGGYIKWWNV 1193
Score = 44.0 bits (99), Expect = 0.004
Identities = 33/146 (22%), Positives = 58/146 (39%), Gaps = 4/146 (2%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
GQ + + Q++ + K+ K H +LC + + +++ T S D V +W+
Sbjct: 616 GQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNS 675
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRS---LVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
T + EH V C N S L+ +G D + + L + H S
Sbjct: 676 MTGELVHTYDEHSEQVNC-CHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNS 734
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWN 806
V + D + + S DGT+ W+
Sbjct: 735 VNHCRFSPDDKLLASCSADGTLKLWD 760
Score = 42.3 bits (95), Expect = 0.012
Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 9/147 (6%)
Query: 988 GLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYK 1047
G V+VW + T + H G + S + S S D+T +W P +
Sbjct: 1054 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1113
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH---------SATGPSASIDVT 1098
GH+ ++ D + D + +W V +G +LH +AT D+
Sbjct: 1114 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1173
Query: 1099 LNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+ +L ++ W++ G++S+
Sbjct: 1174 FSPDGKMLISAGGYIKWWNVVTGESSQ 1200
Score = 41.5 bits (93), Expect = 0.021
Identities = 51/261 (19%), Positives = 100/261 (38%), Gaps = 19/261 (7%)
Query: 918 LAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRD 977
+ A + V +F T+D + + T + E S+ + S
Sbjct: 642 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSH 701
Query: 978 GQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL 1037
L A+G + +++W L+ + T+ GH + FSP++ L+ S S D T+ +W
Sbjct: 702 HLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDA 761
Query: 1038 --ADNSPSLTYK-----------GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIV 1084
A+ S+ K ++ +DG R M + + + + SG++
Sbjct: 762 TSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLL 821
Query: 1085 LHSATGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFA 1141
TG ++I D + AV++ V +W+ D R H +
Sbjct: 822 GEIHTGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCR---GHLSWVHGVM 878
Query: 1142 LTADSQHVVTGSMDMSLKVWK 1162
+ D +T S D ++++W+
Sbjct: 879 FSPDGSSFLTSSDDQTIRLWE 899
Score = 41.1 bits (92), Expect = 0.028
Identities = 40/199 (20%), Positives = 79/199 (39%), Gaps = 7/199 (3%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
L+P Q++ G ++ +++N + H ++ + T + + L++ S+D +
Sbjct: 958 LSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQ 1017
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
VW+ K L + ++ S ++S D V + +++ G H+G
Sbjct: 1018 VWNWQ--LDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1075
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV---TAGVPIHIFDVTDDNVFLLT 836
+V S + D F + S D T W+ + L + V F V D+ L T
Sbjct: 1076 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSV--DSTLLAT 1133
Query: 837 LQGDNELHLRTFITGTYLH 855
+ E+ + G LH
Sbjct: 1134 GDDNGEIRIWNVSNGELLH 1152
Score = 40.3 bits (90), Expect = 0.050
Identities = 46/220 (20%), Positives = 88/220 (40%), Gaps = 17/220 (7%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVI 752
H+ ++ C + + Q + + D ++ V+ T +I H VLC A + +
Sbjct: 603 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 662
Query: 753 SGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN--IFITGSQDGTVCTWNVENF 810
+ D V I + + G LV D H V + + TGS D + W++
Sbjct: 663 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 722
Query: 811 TLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGT----------YLH---P 856
+T+ ++ + D+ L + D L L + +L+ P
Sbjct: 723 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDP 782
Query: 857 LKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
+ + VKC + D +R+ V A +I+L+ +H++ LL
Sbjct: 783 QEDMEVIVKCCSWSADGARIMV-AAKNKIFLFDIHTSGLL 821
Score = 33.5 bits (73), Expect = 5.7
Identities = 17/73 (23%), Positives = 35/73 (47%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+P V+A S +LW+ S SKV +GH + + + + LT S+D ++ +
Sbjct: 838 SPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRL 897
Query: 721 WDLHTLAVKTKIL 733
W+ + + ++
Sbjct: 898 WETKKVCKNSAVM 910
>BC025392-1|AAH25392.1| 620|Homo sapiens WD repeat domain 16 protein.
Length = 620
Score = 68.9 bits (161), Expect = 1e-10
Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 10/202 (4%)
Query: 967 IPISCLEVSRDGQLGASGCARGLVRVWQLS--THRLQATLNGHIGHITCVTFSPNNLLVL 1024
I ++ + + D + SG G VRVWQ+ T +L+ L H ++C+ NN +
Sbjct: 418 IGVTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECV 477
Query: 1025 SGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIV 1084
+ S D T ++W L + ++ Q + + + ++S R + W V G V
Sbjct: 478 TASTDGTCIIWDLVRLRRNQMILA-NTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGTV 536
Query: 1085 LH----SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCF 1140
+ S +G +D+T + V D+ V++W G E V H+ IT
Sbjct: 537 IRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEG---EVTHVGVGHSGNITRI 593
Query: 1141 ALTADSQHVVTGSMDMSLKVWK 1162
++ +Q++V+ S D ++ WK
Sbjct: 594 RISPGNQYIVSVSADGAILRWK 615
Score = 63.7 bits (148), Expect = 5e-09
Identities = 37/136 (27%), Positives = 63/136 (46%), Gaps = 4/136 (2%)
Query: 674 GDPQLWHI--MSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTK 731
G+ ++W I + K H S+ C+ V R ++ +T S D + I+WDL L
Sbjct: 439 GEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECVTASTDGTCIIWDLVRLRRNQM 498
Query: 732 ILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH-RGSVTSVKVIQDG 790
IL + CV +I+ G D + + DG ++ +L+ GS+ + + Q+G
Sbjct: 499 ILANTL-FQCVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEG 557
Query: 791 NIFITGSQDGTVCTWN 806
F+TG D V W+
Sbjct: 558 VHFVTGGNDHLVKVWD 573
Score = 60.5 bits (140), Expect = 4e-08
Identities = 62/291 (21%), Positives = 112/291 (38%), Gaps = 13/291 (4%)
Query: 1009 GHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSS 1068
G IT +T L G+E+ + D +L H A++ ++ ++
Sbjct: 291 GGITSITLRGEGHQFLVGTEESHIYRVSFTDFKETLIATCHFDAVKDIVFPFGTAELFAT 350
Query: 1069 DRARNVHVWLVDSGIVLHSATGPSAS---IDVTLNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+++ VW S L T P+ + ID + K + + D +R ++ G
Sbjct: 351 CAKKDIRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAFAPETGRLMY 410
Query: 1126 DNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKL--DGGKLSQVLVGHSDIVTCVA 1183
+ H +T A T+D + V++G + ++VW++ KL + L H V+C+
Sbjct: 411 VINNA--HRIGVTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIR 468
Query: 1184 VSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTL 1243
V N + V+ S D I+WD+ CV + ++ D+ +
Sbjct: 469 VK-RNNEECVTASTDGTCIIWDL-VRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKI 526
Query: 1244 IIWETKRGLALTSF--SLHVPLLGFQITSDCARVVVHLLDRGCLPIIWLHN 1292
WE G + SL + G IT + V D L +W +N
Sbjct: 527 AYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDH--LVKVWDYN 575
Score = 50.8 bits (116), Expect = 4e-05
Identities = 29/77 (37%), Positives = 43/77 (55%), Gaps = 7/77 (9%)
Query: 969 ISCLEVSRDGQLGASGCARGL-----VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLV 1023
+SCL +SR G+ ASG + + +W L A L+ H G I + FSPN+L +
Sbjct: 67 VSCLAISRSGEYIASGQVTFMGFKVDIILWDYKNRELLARLSLHKGKIEALAFSPNDLYL 126
Query: 1024 LS--GSEDRTVVVWQLA 1038
+S G +D +VVVW +A
Sbjct: 127 VSLGGPDDGSVVVWSIA 143
Score = 48.4 bits (110), Expect = 2e-04
Identities = 56/274 (20%), Positives = 105/274 (38%), Gaps = 20/274 (7%)
Query: 985 CARGLVRVWQLSTHRLQATLNGHIGHITC--VTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
CA+ +RVW S++R L + ++TC + F + ++S D + + A +
Sbjct: 351 CAKKDIRVWHTSSNR--ELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAF--APETG 406
Query: 1043 SLTY---KGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGI-----VLHSATGPSAS 1094
L Y H + + SD +R +S V VW + L +
Sbjct: 407 RLMYVINNAHRIGVTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSC 466
Query: 1095 IDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSM 1154
I V N + V + D + IW L N+ +++ C + ++T
Sbjct: 467 IRVKRNNEECVTASTDGTCIIWDLV---RLRRNQMILANT-LFQCVCYHPEEFQIITSGT 522
Query: 1155 DMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNK-TQVVSGSWDCNLIVWDINTXXXXX 1213
D + W++ G + + L G S + + IT + V+G D + VWD N
Sbjct: 523 DRKIAYWEVFDGTVIRELEG-SLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTH 581
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+T ++++ VS + D ++ W+
Sbjct: 582 VGVGHSGNITRIRISPGNQYIVSVSADGAILRWK 615
Score = 38.7 bits (86), Expect = 0.15
Identities = 23/115 (20%), Positives = 53/115 (46%), Gaps = 9/115 (7%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSE--- 714
L+ P +H++ G L ++ + + +GH ++ C+ ++R +Y+ +G
Sbjct: 30 LKCHPDQEHMIYP--LGCTVLIQAINTKEQNFLQGHGNNVSCLAISRSGEYIASGQVTFM 87
Query: 715 --DTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVIS--GGDDSAVIITSL 765
+I+WD + ++ H + +A N ++S G DD +V++ S+
Sbjct: 88 GFKVDIILWDYKNRELLARLSLHKGKIEALAFSPNDLYLVSLGGPDDGSVVVWSI 142
Score = 38.3 bits (85), Expect = 0.20
Identities = 20/108 (18%), Positives = 46/108 (42%), Gaps = 1/108 (0%)
Query: 699 CMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSL-VISGGDD 757
C+C E ++T D + W++ V ++ ++ + I + ++GG+D
Sbjct: 507 CVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGND 566
Query: 758 SAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
V + +G + H G++T +++ ++ S DG + W
Sbjct: 567 HLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAILRW 614
Score = 37.5 bits (83), Expect = 0.35
Identities = 37/189 (19%), Positives = 75/189 (39%), Gaps = 7/189 (3%)
Query: 675 DPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE 734
D ++WH SN ++ + + + R+ + +++ D + + T + I
Sbjct: 355 DIRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAFAPETGRLMYVINN 414
Query: 735 -HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH----HRGSVTSVKVIQD 789
H V +A + VISGG + V + + G KL+ H+ SV+ ++V ++
Sbjct: 415 AHRIGVTAIATTSDCKRVISGGGEGEVRVWQI--GCQTQKLEEALKEHKSSVSCIRVKRN 472
Query: 790 GNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFI 849
+T S DGT W++ + A + ++T D ++
Sbjct: 473 NEECVTASTDGTCIIWDLVRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVF 532
Query: 850 TGTYLHPLK 858
GT + L+
Sbjct: 533 DGTVIRELE 541
Score = 36.7 bits (81), Expect = 0.61
Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Query: 679 WHIMSNSKVHTFKGH-SGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIA 737
W + + + +G SGSI M +T+E + +TG D V VWD + V + H
Sbjct: 529 WEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSG 588
Query: 738 PVLCVAAIVNRSLVISGGDDSAVI 761
+ + ++S D A++
Sbjct: 589 NITRIRISPGNQYIVSVSADGAIL 612
Score = 34.3 bits (75), Expect = 3.3
Identities = 15/64 (23%), Positives = 31/64 (48%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ + G H V + ++W H GHSG+I + ++ +QY+++ S D +
Sbjct: 551 MDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGA 610
Query: 718 VIVW 721
++ W
Sbjct: 611 ILRW 614
>AL031282-15|CAI20051.1| 197|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 197
Score = 68.9 bits (161), Expect = 1e-10
Identities = 51/204 (25%), Positives = 93/204 (45%), Gaps = 14/204 (6%)
Query: 1009 GHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSS 1068
G+++C F +N +V S S D T +W + + T+ GH+ + +L + D R +S
Sbjct: 1 GYLSCCRFLDDNQIVTS-SGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSG 59
Query: 1069 DRARNVHVWLVDSGIVLHSATGPSASIDVTL----NMKYAVLSDGDNSVRIWSLAGGDNS 1124
+ +W V G+ + TG + I+ +A SD D + R++ L +
Sbjct: 60 ACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSD-DATCRLFDL----RA 114
Query: 1125 EDNRRSVSHAE---RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTC 1181
+ + SH IT + + + ++ G D + VW + VL GH + V+C
Sbjct: 115 DQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSC 174
Query: 1182 VAVSITNKTQVVSGSWDCNLIVWD 1205
+ V+ + V +GSWD L +W+
Sbjct: 175 LGVT-DDGMAVATGSWDSFLKIWN 197
Score = 68.1 bits (159), Expect = 2e-10
Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 9/198 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + T GH G + ++ +P+ L +SG+
Sbjct: 3 LSCCRFLDDNQIVTSS-GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 61
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRR-AMSSDRAR-NVHVWLVDSGIVLH 1086
D + +W + + T+ GH S I + +G A SD A + D ++ +
Sbjct: 62 DASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY 121
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V+ + +L G D + +W D + H R++C +T
Sbjct: 122 SHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRA---GVLAGHDNRVSCLGVT 178
Query: 1144 ADSQHVVTGSMDMSLKVW 1161
D V TGS D LK+W
Sbjct: 179 DDGMAVATGSWDSFLKIW 196
Score = 57.6 bits (133), Expect = 3e-07
Identities = 43/183 (23%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Query: 669 LAPSAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+ S+GD LW I + + TF GH+G ++ + + +++ ++G+ D S +WD+
Sbjct: 14 IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 73
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSV 784
+ H + + + N + +G DD+ + L D L+T D+ +TSV
Sbjct: 74 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSV 133
Query: 785 KVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQGDNE 842
+ G + + G D W+ + V AG + VTDD + + T D+
Sbjct: 134 SFSKSGRLLLAGYDDFNCNVWDALKAD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSF 192
Query: 843 LHL 845
L +
Sbjct: 193 LKI 195
Score = 57.2 bits (132), Expect = 4e-07
Identities = 43/195 (22%), Positives = 79/195 (40%), Gaps = 3/195 (1%)
Query: 698 LCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDD 757
L C + ++T S DT+ +WD+ T T H V+ ++ + L +SG D
Sbjct: 3 LSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACD 62
Query: 758 SAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
++ + + +G H + ++ +GN F TGS D T +++ L T +
Sbjct: 63 ASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS 122
Query: 818 -AGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFCVAHDSS 874
+ I V+ L L G ++ + + + L H +V C V D
Sbjct: 123 HDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGM 182
Query: 875 RVAVGCADQRIYLYS 889
VA G D + +++
Sbjct: 183 AVATGSWDSFLKIWN 197
Score = 49.6 bits (113), Expect = 8e-05
Identities = 38/151 (25%), Positives = 60/151 (39%), Gaps = 2/151 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP + V +LW + TF GH I +C TGS+D +
Sbjct: 47 LSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDAT 106
Query: 718 VIVWDLHT-LAVKTKILEH-IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
++DL + T ++ I + V+ + L+++G DD + + L
Sbjct: 107 CRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLA 166
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 167 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 197
Score = 44.8 bits (101), Expect = 0.002
Identities = 29/145 (20%), Positives = 55/145 (37%), Gaps = 6/145 (4%)
Query: 1105 VLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLD 1164
V S GD + +W + G + H + +L D++ V+G+ D S K+W +
Sbjct: 15 VTSSGDTTCALWDIETG---QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVR 71
Query: 1165 GGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KV 1222
G Q GH + + N +GS D ++D+ +
Sbjct: 72 EGMCRQTFTGHESDINAICF-FPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGI 130
Query: 1223 TCVKVTGDGTIAVSCAEDKTLIIWE 1247
T V + G + ++ +D +W+
Sbjct: 131 TSVSFSKSGRLLLAGYDDFNCNVWD 155
Score = 41.9 bits (94), Expect = 0.016
Identities = 39/191 (20%), Positives = 75/191 (39%), Gaps = 9/191 (4%)
Query: 1061 DGRRAMSSDRARNVHVWLVDSG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
D + ++S +W +++G TG S+ + + + V D S ++W
Sbjct: 10 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 69
Query: 1118 LAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSD 1177
+ G + H I + TGS D + +++ L + + H +
Sbjct: 70 VREG---MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ-ELMTYSHDN 125
Query: 1178 IVTCV-AVSITNKTQVV-SGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAV 1235
I+ + +VS + +++ +G D N VWD +V+C+ VT DG
Sbjct: 126 IICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVA 185
Query: 1236 SCAEDKTLIIW 1246
+ + D L IW
Sbjct: 186 TGSWDSFLKIW 196
Score = 41.1 bits (92), Expect = 0.028
Identities = 25/123 (20%), Positives = 58/123 (47%), Gaps = 4/123 (3%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV-VSG 1195
++C D+Q +VT S D + +W ++ G+ + GH+ V +++S+ T++ VSG
Sbjct: 3 LSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFTGHTGDV--MSLSLAPDTRLFVSG 59
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALT 1255
+ D + +WD+ + + +G + ++D T +++ + L
Sbjct: 60 ACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELM 119
Query: 1256 SFS 1258
++S
Sbjct: 120 TYS 122
Score = 37.5 bits (83), Expect = 0.35
Identities = 18/70 (25%), Positives = 31/70 (44%)
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
Q+V+ S D +WDI T V + + D + VS A D + +W+ +
Sbjct: 13 QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVRE 72
Query: 1251 GLALTSFSLH 1260
G+ +F+ H
Sbjct: 73 GMCRQTFTGH 82
>AK094847-1|BAC04435.1| 630|Homo sapiens protein ( Homo sapiens cDNA
FLJ37528 fis, clone BRCAN2012408. ).
Length = 630
Score = 68.9 bits (161), Expect = 1e-10
Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 10/202 (4%)
Query: 967 IPISCLEVSRDGQLGASGCARGLVRVWQLS--THRLQATLNGHIGHITCVTFSPNNLLVL 1024
I ++ + + D + SG G VRVWQ+ T +L+ L H ++C+ NN +
Sbjct: 428 IGVTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECV 487
Query: 1025 SGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIV 1084
+ S D T ++W L + ++ Q + + + ++S R + W V G V
Sbjct: 488 TASTDGTCIIWDLVRLRRNQMILA-NTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGTV 546
Query: 1085 LH----SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCF 1140
+ S +G +D+T + V D+ V++W G E V H+ IT
Sbjct: 547 IRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEG---EVTHVGVGHSGNITRI 603
Query: 1141 ALTADSQHVVTGSMDMSLKVWK 1162
++ +Q++V+ S D ++ WK
Sbjct: 604 RISPGNQYIVSVSADGAILRWK 625
Score = 63.7 bits (148), Expect = 5e-09
Identities = 37/136 (27%), Positives = 63/136 (46%), Gaps = 4/136 (2%)
Query: 674 GDPQLWHI--MSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTK 731
G+ ++W I + K H S+ C+ V R ++ +T S D + I+WDL L
Sbjct: 449 GEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECVTASTDGTCIIWDLVRLRRNQM 508
Query: 732 ILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH-RGSVTSVKVIQDG 790
IL + CV +I+ G D + + DG ++ +L+ GS+ + + Q+G
Sbjct: 509 ILANTL-FQCVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEG 567
Query: 791 NIFITGSQDGTVCTWN 806
F+TG D V W+
Sbjct: 568 VHFVTGGNDHLVKVWD 583
Score = 60.5 bits (140), Expect = 4e-08
Identities = 62/291 (21%), Positives = 112/291 (38%), Gaps = 13/291 (4%)
Query: 1009 GHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSS 1068
G IT +T L G+E+ + D +L H A++ ++ ++
Sbjct: 301 GGITSITLRGEGHQFLVGTEESHIYRVSFTDFKETLIATCHFDAVKDIVFPFGTAELFAT 360
Query: 1069 DRARNVHVWLVDSGIVLHSATGPSAS---IDVTLNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+++ VW S L T P+ + ID + K + + D +R ++ G
Sbjct: 361 CAKKDIRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAFAPETGRLMY 420
Query: 1126 DNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKL--DGGKLSQVLVGHSDIVTCVA 1183
+ H +T A T+D + V++G + ++VW++ KL + L H V+C+
Sbjct: 421 VINNA--HRIGVTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIR 478
Query: 1184 VSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTL 1243
V N + V+ S D I+WD+ CV + ++ D+ +
Sbjct: 479 VK-RNNEECVTASTDGTCIIWDL-VRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKI 536
Query: 1244 IIWETKRGLALTSF--SLHVPLLGFQITSDCARVVVHLLDRGCLPIIWLHN 1292
WE G + SL + G IT + V D L +W +N
Sbjct: 537 AYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDH--LVKVWDYN 585
Score = 50.8 bits (116), Expect = 4e-05
Identities = 29/77 (37%), Positives = 43/77 (55%), Gaps = 7/77 (9%)
Query: 969 ISCLEVSRDGQLGASGCARGL-----VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLV 1023
+SCL +SR G+ ASG + + +W L A L+ H G I + FSPN+L +
Sbjct: 77 VSCLAISRSGEYIASGQVTFMGFKADIILWDYKNRELLARLSLHKGKIEALAFSPNDLYL 136
Query: 1024 LS--GSEDRTVVVWQLA 1038
+S G +D +VVVW +A
Sbjct: 137 VSLGGPDDGSVVVWSIA 153
Score = 48.4 bits (110), Expect = 2e-04
Identities = 56/274 (20%), Positives = 105/274 (38%), Gaps = 20/274 (7%)
Query: 985 CARGLVRVWQLSTHRLQATLNGHIGHITC--VTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
CA+ +RVW S++R L + ++TC + F + ++S D + + A +
Sbjct: 361 CAKKDIRVWHTSSNR--ELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAF--APETG 416
Query: 1043 SLTY---KGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGI-----VLHSATGPSAS 1094
L Y H + + SD +R +S V VW + L +
Sbjct: 417 RLMYVINNAHRIGVTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSC 476
Query: 1095 IDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSM 1154
I V N + V + D + IW L N+ +++ C + ++T
Sbjct: 477 IRVKRNNEECVTASTDGTCIIWDLV---RLRRNQMILANT-LFQCVCYHPEEFQIITSGT 532
Query: 1155 DMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNK-TQVVSGSWDCNLIVWDINTXXXXX 1213
D + W++ G + + L G S + + IT + V+G D + VWD N
Sbjct: 533 DRKIAYWEVFDGTVIRELEG-SLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTH 591
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+T ++++ VS + D ++ W+
Sbjct: 592 VGVGHSGNITRIRISPGNQYIVSVSADGAILRWK 625
Score = 38.7 bits (86), Expect = 0.15
Identities = 23/115 (20%), Positives = 53/115 (46%), Gaps = 9/115 (7%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSE--- 714
L+ P +H++ G L ++ + + +GH ++ C+ ++R +Y+ +G
Sbjct: 40 LKCHPDQEHMIYP--LGCTVLIQAINTKEQNFLQGHGNNVSCLAISRSGEYIASGQVTFM 97
Query: 715 --DTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVIS--GGDDSAVIITSL 765
+I+WD + ++ H + +A N ++S G DD +V++ S+
Sbjct: 98 GFKADIILWDYKNRELLARLSLHKGKIEALAFSPNDLYLVSLGGPDDGSVVVWSI 152
Score = 38.3 bits (85), Expect = 0.20
Identities = 20/108 (18%), Positives = 46/108 (42%), Gaps = 1/108 (0%)
Query: 699 CMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSL-VISGGDD 757
C+C E ++T D + W++ V ++ ++ + I + ++GG+D
Sbjct: 517 CVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGND 576
Query: 758 SAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
V + +G + H G++T +++ ++ S DG + W
Sbjct: 577 HLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAILRW 624
Score = 37.5 bits (83), Expect = 0.35
Identities = 37/189 (19%), Positives = 75/189 (39%), Gaps = 7/189 (3%)
Query: 675 DPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE 734
D ++WH SN ++ + + + R+ + +++ D + + T + I
Sbjct: 365 DIRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAFAPETGRLMYVINN 424
Query: 735 -HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH----HRGSVTSVKVIQD 789
H V +A + VISGG + V + + G KL+ H+ SV+ ++V ++
Sbjct: 425 AHRIGVTAIATTSDCKRVISGGGEGEVRVWQI--GCQTQKLEEALKEHKSSVSCIRVKRN 482
Query: 790 GNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFI 849
+T S DGT W++ + A + ++T D ++
Sbjct: 483 NEECVTASTDGTCIIWDLVRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVF 542
Query: 850 TGTYLHPLK 858
GT + L+
Sbjct: 543 DGTVIRELE 551
Score = 36.7 bits (81), Expect = 0.61
Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Query: 679 WHIMSNSKVHTFKGH-SGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIA 737
W + + + +G SGSI M +T+E + +TG D V VWD + V + H
Sbjct: 539 WEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSG 598
Query: 738 PVLCVAAIVNRSLVISGGDDSAVI 761
+ + ++S D A++
Sbjct: 599 NITRIRISPGNQYIVSVSADGAIL 622
Score = 34.3 bits (75), Expect = 3.3
Identities = 15/64 (23%), Positives = 31/64 (48%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ + G H V + ++W H GHSG+I + ++ +QY+++ S D +
Sbjct: 561 MDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGA 620
Query: 718 VIVW 721
++ W
Sbjct: 621 ILRW 624
>AK074435-1|BAB85083.1| 412|Homo sapiens protein ( Homo sapiens cDNA
FLJ23855 fis, clone LNG06370. ).
Length = 412
Score = 68.9 bits (161), Expect = 1e-10
Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 10/202 (4%)
Query: 967 IPISCLEVSRDGQLGASGCARGLVRVWQLS--THRLQATLNGHIGHITCVTFSPNNLLVL 1024
I ++ + + D + SG G VRVWQ+ T +L+ L H ++C+ NN +
Sbjct: 210 IGVTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECV 269
Query: 1025 SGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIV 1084
+ S D T ++W L + ++ Q + + + ++S R + W V G V
Sbjct: 270 TASTDGTCIIWDLVRLRRNQMILA-NTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGTV 328
Query: 1085 LH----SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCF 1140
+ S +G +D+T + V D+ V++W G E V H+ IT
Sbjct: 329 IRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEG---EVTHVGVGHSGNITRI 385
Query: 1141 ALTADSQHVVTGSMDMSLKVWK 1162
++ +Q++V+ S D ++ WK
Sbjct: 386 RISPGNQYIVSVSADGAILRWK 407
Score = 63.7 bits (148), Expect = 5e-09
Identities = 37/136 (27%), Positives = 63/136 (46%), Gaps = 4/136 (2%)
Query: 674 GDPQLWHI--MSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTK 731
G+ ++W I + K H S+ C+ V R ++ +T S D + I+WDL L
Sbjct: 231 GEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECVTASTDGTCIIWDLVRLRRNQM 290
Query: 732 ILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH-RGSVTSVKVIQDG 790
IL + CV +I+ G D + + DG ++ +L+ GS+ + + Q+G
Sbjct: 291 ILANTL-FQCVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEG 349
Query: 791 NIFITGSQDGTVCTWN 806
F+TG D V W+
Sbjct: 350 VHFVTGGNDHLVKVWD 365
Score = 60.5 bits (140), Expect = 4e-08
Identities = 62/291 (21%), Positives = 112/291 (38%), Gaps = 13/291 (4%)
Query: 1009 GHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSS 1068
G IT +T L G+E+ + D +L H A++ ++ ++
Sbjct: 83 GGITSITLRGEGHQFLVGTEESHIYRVSFTDFKETLIATCHFDAVKDIVFPFGTAELFAT 142
Query: 1069 DRARNVHVWLVDSGIVLHSATGPSAS---IDVTLNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+++ VW S L T P+ + ID + K + + D +R ++ G
Sbjct: 143 CAKKDIRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAFAPETGRLMY 202
Query: 1126 DNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKL--DGGKLSQVLVGHSDIVTCVA 1183
+ H +T A T+D + V++G + ++VW++ KL + L H V+C+
Sbjct: 203 VINNA--HRIGVTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIR 260
Query: 1184 VSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTL 1243
V N + V+ S D I+WD+ CV + ++ D+ +
Sbjct: 261 VK-RNNEECVTASTDGTCIIWDL-VRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKI 318
Query: 1244 IIWETKRGLALTSF--SLHVPLLGFQITSDCARVVVHLLDRGCLPIIWLHN 1292
WE G + SL + G IT + V D L +W +N
Sbjct: 319 AYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDH--LVKVWDYN 367
Score = 48.4 bits (110), Expect = 2e-04
Identities = 56/274 (20%), Positives = 105/274 (38%), Gaps = 20/274 (7%)
Query: 985 CARGLVRVWQLSTHRLQATLNGHIGHITC--VTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
CA+ +RVW S++R L + ++TC + F + ++S D + + A +
Sbjct: 143 CAKKDIRVWHTSSNR--ELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAF--APETG 198
Query: 1043 SLTY---KGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGI-----VLHSATGPSAS 1094
L Y H + + SD +R +S V VW + L +
Sbjct: 199 RLMYVINNAHRIGVTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSC 258
Query: 1095 IDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSM 1154
I V N + V + D + IW L N+ +++ C + ++T
Sbjct: 259 IRVKRNNEECVTASTDGTCIIWDLV---RLRRNQMILANT-LFQCVCYHPEEFQIITSGT 314
Query: 1155 DMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNK-TQVVSGSWDCNLIVWDINTXXXXX 1213
D + W++ G + + L G S + + IT + V+G D + VWD N
Sbjct: 315 DRKIAYWEVFDGTVIRELEG-SLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTH 373
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+T ++++ VS + D ++ W+
Sbjct: 374 VGVGHSGNITRIRISPGNQYIVSVSADGAILRWK 407
Score = 38.3 bits (85), Expect = 0.20
Identities = 20/108 (18%), Positives = 46/108 (42%), Gaps = 1/108 (0%)
Query: 699 CMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSL-VISGGDD 757
C+C E ++T D + W++ V ++ ++ + I + ++GG+D
Sbjct: 299 CVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGND 358
Query: 758 SAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
V + +G + H G++T +++ ++ S DG + W
Sbjct: 359 HLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAILRW 406
Score = 37.5 bits (83), Expect = 0.35
Identities = 37/189 (19%), Positives = 75/189 (39%), Gaps = 7/189 (3%)
Query: 675 DPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE 734
D ++WH SN ++ + + + R+ + +++ D + + T + I
Sbjct: 147 DIRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAFAPETGRLMYVINN 206
Query: 735 -HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH----HRGSVTSVKVIQD 789
H V +A + VISGG + V + + G KL+ H+ SV+ ++V ++
Sbjct: 207 AHRIGVTAIATTSDCKRVISGGGEGEVRVWQI--GCQTQKLEEALKEHKSSVSCIRVKRN 264
Query: 790 GNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFI 849
+T S DGT W++ + A + ++T D ++
Sbjct: 265 NEECVTASTDGTCIIWDLVRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVF 324
Query: 850 TGTYLHPLK 858
GT + L+
Sbjct: 325 DGTVIRELE 333
Score = 36.7 bits (81), Expect = 0.61
Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Query: 679 WHIMSNSKVHTFKGH-SGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIA 737
W + + + +G SGSI M +T+E + +TG D V VWD + V + H
Sbjct: 321 WEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSG 380
Query: 738 PVLCVAAIVNRSLVISGGDDSAVI 761
+ + ++S D A++
Sbjct: 381 NITRIRISPGNQYIVSVSADGAIL 404
Score = 34.3 bits (75), Expect = 3.3
Identities = 15/64 (23%), Positives = 31/64 (48%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ + G H V + ++W H GHSG+I + ++ +QY+++ S D +
Sbjct: 343 MDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGA 402
Query: 718 VIVW 721
++ W
Sbjct: 403 ILRW 406
>AB065281-1|BAB83743.1| 620|Homo sapiens WDR16 protein.
Length = 620
Score = 68.9 bits (161), Expect = 1e-10
Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 10/202 (4%)
Query: 967 IPISCLEVSRDGQLGASGCARGLVRVWQLS--THRLQATLNGHIGHITCVTFSPNNLLVL 1024
I ++ + + D + SG G VRVWQ+ T +L+ L H ++C+ NN +
Sbjct: 418 IGVTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECV 477
Query: 1025 SGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIV 1084
+ S D T ++W L + ++ Q + + + ++S R + W V G V
Sbjct: 478 TASTDGTCIIWDLVRLRRNQMILA-NTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGTV 536
Query: 1085 LH----SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCF 1140
+ S +G +D+T + V D+ V++W G E V H+ IT
Sbjct: 537 IRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEG---EVTHVGVGHSGNITRI 593
Query: 1141 ALTADSQHVVTGSMDMSLKVWK 1162
++ +Q++V+ S D ++ WK
Sbjct: 594 RISPGNQYIVSVSADGAILRWK 615
Score = 63.7 bits (148), Expect = 5e-09
Identities = 37/136 (27%), Positives = 63/136 (46%), Gaps = 4/136 (2%)
Query: 674 GDPQLWHI--MSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTK 731
G+ ++W I + K H S+ C+ V R ++ +T S D + I+WDL L
Sbjct: 439 GEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECVTASTDGTCIIWDLVRLRRNQM 498
Query: 732 ILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH-RGSVTSVKVIQDG 790
IL + CV +I+ G D + + DG ++ +L+ GS+ + + Q+G
Sbjct: 499 ILANTL-FQCVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEG 557
Query: 791 NIFITGSQDGTVCTWN 806
F+TG D V W+
Sbjct: 558 VHFVTGGNDHLVKVWD 573
Score = 60.9 bits (141), Expect = 3e-08
Identities = 62/291 (21%), Positives = 112/291 (38%), Gaps = 13/291 (4%)
Query: 1009 GHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSS 1068
G IT +T L G+E+ + D +L H A++ ++ ++
Sbjct: 291 GGITSITLRGEGHQFLVGTEESHIYRVSFTDFKETLIATCHFDAVEDIVFPFGTAELFAT 350
Query: 1069 DRARNVHVWLVDSGIVLHSATGPSAS---IDVTLNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+++ VW S L T P+ + ID + K + + D +R ++ G
Sbjct: 351 CAKKDIRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAFAPETGRLMY 410
Query: 1126 DNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKL--DGGKLSQVLVGHSDIVTCVA 1183
+ H +T A T+D + V++G + ++VW++ KL + L H V+C+
Sbjct: 411 VINNA--HRIGVTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIR 468
Query: 1184 VSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTL 1243
V N + V+ S D I+WD+ CV + ++ D+ +
Sbjct: 469 VK-RNNEECVTASTDGTCIIWDL-VRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKI 526
Query: 1244 IIWETKRGLALTSF--SLHVPLLGFQITSDCARVVVHLLDRGCLPIIWLHN 1292
WE G + SL + G IT + V D L +W +N
Sbjct: 527 AYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDH--LVKVWDYN 575
Score = 50.8 bits (116), Expect = 4e-05
Identities = 29/77 (37%), Positives = 43/77 (55%), Gaps = 7/77 (9%)
Query: 969 ISCLEVSRDGQLGASGCARGL-----VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLV 1023
+SCL +SR G+ ASG + + +W L A L+ H G I + FSPN+L +
Sbjct: 67 VSCLAISRSGEYIASGQVTFMGFKADIILWDYKNRELLARLSLHKGKIEALAFSPNDLYL 126
Query: 1024 LS--GSEDRTVVVWQLA 1038
+S G +D +VVVW +A
Sbjct: 127 VSLGGPDDGSVVVWSIA 143
Score = 48.4 bits (110), Expect = 2e-04
Identities = 56/274 (20%), Positives = 105/274 (38%), Gaps = 20/274 (7%)
Query: 985 CARGLVRVWQLSTHRLQATLNGHIGHITC--VTFSPNNLLVLSGSEDRTVVVWQLADNSP 1042
CA+ +RVW S++R L + ++TC + F + ++S D + + A +
Sbjct: 351 CAKKDIRVWHTSSNR--ELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAF--APETG 406
Query: 1043 SLTY---KGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGI-----VLHSATGPSAS 1094
L Y H + + SD +R +S V VW + L +
Sbjct: 407 RLMYVINNAHRIGVTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSC 466
Query: 1095 IDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSM 1154
I V N + V + D + IW L N+ +++ C + ++T
Sbjct: 467 IRVKRNNEECVTASTDGTCIIWDLV---RLRRNQMILANT-LFQCVCYHPEEFQIITSGT 522
Query: 1155 DMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNK-TQVVSGSWDCNLIVWDINTXXXXX 1213
D + W++ G + + L G S + + IT + V+G D + VWD N
Sbjct: 523 DRKIAYWEVFDGTVIRELEG-SLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTH 581
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+T ++++ VS + D ++ W+
Sbjct: 582 VGVGHSGNITRIRISPGNQYIVSVSADGAILRWK 615
Score = 38.7 bits (86), Expect = 0.15
Identities = 23/115 (20%), Positives = 53/115 (46%), Gaps = 9/115 (7%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSE--- 714
L+ P +H++ G L ++ + + +GH ++ C+ ++R +Y+ +G
Sbjct: 30 LKCHPDQEHMIYP--LGCTVLIQAINTKEQNFLQGHGNNVSCLAISRSGEYIASGQVTFM 87
Query: 715 --DTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVIS--GGDDSAVIITSL 765
+I+WD + ++ H + +A N ++S G DD +V++ S+
Sbjct: 88 GFKADIILWDYKNRELLARLSLHKGKIEALAFSPNDLYLVSLGGPDDGSVVVWSI 142
Score = 38.3 bits (85), Expect = 0.20
Identities = 20/108 (18%), Positives = 46/108 (42%), Gaps = 1/108 (0%)
Query: 699 CMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSL-VISGGDD 757
C+C E ++T D + W++ V ++ ++ + I + ++GG+D
Sbjct: 507 CVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGND 566
Query: 758 SAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
V + +G + H G++T +++ ++ S DG + W
Sbjct: 567 HLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAILRW 614
Score = 37.5 bits (83), Expect = 0.35
Identities = 37/189 (19%), Positives = 75/189 (39%), Gaps = 7/189 (3%)
Query: 675 DPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE 734
D ++WH SN ++ + + + R+ + +++ D + + T + I
Sbjct: 355 DIRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAFAPETGRLMYVINN 414
Query: 735 -HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH----HRGSVTSVKVIQD 789
H V +A + VISGG + V + + G KL+ H+ SV+ ++V ++
Sbjct: 415 AHRIGVTAIATTSDCKRVISGGGEGEVRVWQI--GCQTQKLEEALKEHKSSVSCIRVKRN 472
Query: 790 GNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFI 849
+T S DGT W++ + A + ++T D ++
Sbjct: 473 NEECVTASTDGTCIIWDLVRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVF 532
Query: 850 TGTYLHPLK 858
GT + L+
Sbjct: 533 DGTVIRELE 541
Score = 36.7 bits (81), Expect = 0.61
Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Query: 679 WHIMSNSKVHTFKGH-SGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIA 737
W + + + +G SGSI M +T+E + +TG D V VWD + V + H
Sbjct: 529 WEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSG 588
Query: 738 PVLCVAAIVNRSLVISGGDDSAVI 761
+ + ++S D A++
Sbjct: 589 NITRIRISPGNQYIVSVSADGAIL 612
Score = 34.3 bits (75), Expect = 3.3
Identities = 15/64 (23%), Positives = 31/64 (48%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ + G H V + ++W H GHSG+I + ++ +QY+++ S D +
Sbjct: 551 MDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGA 610
Query: 718 VIVW 721
++ W
Sbjct: 611 ILRW 614
>AJ243009-1|CAB55585.1| 1248|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1248
Score = 68.5 bits (160), Expect = 2e-10
Identities = 78/382 (20%), Positives = 148/382 (38%), Gaps = 21/382 (5%)
Query: 828 TDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRV--AVGCADQRI 885
TDD F+ T D ++ + +TG +H H +V C + S + A G +D +
Sbjct: 667 TDDR-FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFL 725
Query: 886 YLYSLHSAQLLRTXXXXXXXXXXXXXXXXXFLLAAGGNRVTIYSFHTEDNLTNFRPTKQM 945
L+ L+ + T LLA S + L + T
Sbjct: 726 KLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLA---------SCSADGTLKLWDATSAN 776
Query: 946 KRRQTKSTTNITLLQAEQSDL-IPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATL 1004
+R+ L+ Q D+ + + C S DG A+ + ++ + T L +
Sbjct: 777 ERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGAR-IMVAAKNKIFLFAIHTSGLLGEI 835
Query: 1005 N-GHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR 1063
+ GH I FSP N L + V +W S +GH S + ++ DG
Sbjct: 836 HTGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGS 895
Query: 1064 RAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDN 1123
++S + + +W + +SA +DV ++ D+ R+ + G
Sbjct: 896 SFLTSSDDQTIRLWETKK-VCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLVNGRTG 954
Query: 1124 SEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVA 1183
D ++ A+ ++C L+ Q++ G + ++++ +L ++ Q H V +
Sbjct: 955 QID---YLTEAQ-VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQ 1010
Query: 1184 VSITNKTQVVSGSWDCNLIVWD 1205
+ KT ++S S D + VW+
Sbjct: 1011 FTADEKT-LISSSDDAEIQVWN 1031
Score = 63.7 bits (148), Expect = 5e-09
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 1/147 (0%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKT 1190
+H + + C A + D + + T S+D +K+W G+L HS+ V C + ++
Sbjct: 655 AHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHL 714
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKR 1250
+ +GS DC L +WD+N V + + D + SC+ D TL +W+
Sbjct: 715 LLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATS 774
Query: 1251 GLALTSFSLHVPLLGFQITSDCARVVV 1277
S ++ L + + V+V
Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIV 801
Score = 62.9 bits (146), Expect = 8e-09
Identities = 66/316 (20%), Positives = 126/316 (39%), Gaps = 23/316 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I + S L ++ V +W + A GH+ + V FSP+ L+ S+
Sbjct: 843 IQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSD 902
Query: 1029 DRTVVVWQ---LADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVL 1085
D+T+ +W+ + NS + + Q +M ++ D R + + +G +
Sbjct: 903 DQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVM-----VLAVDHIRRLQLVNGRTGQID 957
Query: 1086 HSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTAD 1145
+ + ++ +++Y D + ++ I L N+ + H + + TAD
Sbjct: 958 YLTEAQVSCCCLSPHLQYIAFGDENGAIEILELV---NNRIFQSRFQHKKTVWHIQFTAD 1014
Query: 1146 SQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
+ +++ S D ++VW K L GH + T + ++++S S+D + VW+
Sbjct: 1015 EKTLISSSDDAEIQVWNWQLDKCI-FLRGHQE--TVKDFRLLKNSRLLSWSFDGTVKVWN 1071
Query: 1206 INTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLG 1265
I T V ++ D T S + DKT IW SF L +PL
Sbjct: 1072 IITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIW---------SFDLLLPLHE 1122
Query: 1266 FQITSDCARVVVHLLD 1281
+ + C R +D
Sbjct: 1123 LRGHNGCVRCSAFSVD 1138
Score = 57.6 bits (133), Expect = 3e-07
Identities = 60/318 (18%), Positives = 128/318 (40%), Gaps = 23/318 (7%)
Query: 951 KSTTNITLLQAE-QSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIG 1009
K+ TN++ L +D + +C S DGQ AS A ++V++ T + H
Sbjct: 601 KNITNLSCLVVRPHTDAVYHACF--SEDGQRIASCGADKTLQVFKAETGEKLLEIKAHED 658
Query: 1010 HITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSD 1069
+ C FS ++ + + S D+ V +W TY HS + + + +
Sbjct: 659 EVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLAT 718
Query: 1070 RARN--VHVWLVDSGIVLHSATGPSASID---VTLNMKYAVLSDGDNSVRIWSLAGGD-- 1122
+ + + +W ++ ++ G + S++ + + K D ++++W +
Sbjct: 719 GSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANER 778
Query: 1123 ----------NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
N ED + + + C + +AD ++ + + G L ++
Sbjct: 779 KSINVKQFFLNLEDPQEDMEVI--VKCCSWSADGARIMVAAKNKIFLFAIHTSGLLGEIH 836
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGT 1232
GH + S N VV+ S C + +W+ ++ V V + DG+
Sbjct: 837 TGHHSTIQYCDFSPQNHLAVVALSQYC-VELWNTDSRSKVADCRGHLSWVHGVMFSPDGS 895
Query: 1233 IAVSCAEDKTLIIWETKR 1250
++ ++D+T+ +WETK+
Sbjct: 896 SFLTSSDDQTIRLWETKK 913
Score = 53.6 bits (123), Expect = 5e-06
Identities = 42/202 (20%), Positives = 91/202 (45%), Gaps = 5/202 (2%)
Query: 697 ILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGD 756
+ C C++ QY+ G E+ ++ + +L + +H V + + +IS D
Sbjct: 964 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 1023
Query: 757 DSAVIITSL-VDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLST 815
D+ + + + +D + L H+ +V +++++ + ++ S DGTV WN+
Sbjct: 1024 DAEIQVWNWQLDKCIF--LRGHQETVKDFRLLKNSRL-LSWSFDGTVKVWNIITGNKEKD 1080
Query: 816 -VTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSS 874
V + D++ D + D + +F LH L+ H V+C + DS+
Sbjct: 1081 FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST 1140
Query: 875 RVAVGCADQRIYLYSLHSAQLL 896
+A G + I ++++ + +LL
Sbjct: 1141 LLATGDDNGEIRIWNVSNGELL 1162
Score = 52.0 bits (119), Expect = 2e-05
Identities = 44/205 (21%), Positives = 86/205 (41%), Gaps = 12/205 (5%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC +S Q A G G + + +L +R+ + H + + F+ + ++S S+
Sbjct: 964 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 1023
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSG-----I 1083
D + VW + + +GH ++ ++ + R +S V VW + +G
Sbjct: 1024 DAEIQVWNWQLDK-CIFLRGHQETVKDFRLLKNSR-LLSWSFDGTVKVWNIITGNKEKDF 1081
Query: 1084 VLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
V H T S D++ + + D + +IWS D H + C A +
Sbjct: 1082 VCHQGT--VLSCDISHDATKFSSTSADKTAKIWSF---DLLLPLHELRGHNGCVRCSAFS 1136
Query: 1144 ADSQHVVTGSMDMSLKVWKLDGGKL 1168
DS + TG + +++W + G+L
Sbjct: 1137 VDSTLLATGDDNGEIRIWNVSNGEL 1161
Score = 49.6 bits (113), Expect = 8e-05
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 10/142 (7%)
Query: 674 GDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKIL 733
G ++W+I++ +K F H G++L ++ ++ + S D + +W L ++
Sbjct: 1065 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1124
Query: 734 EHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALV---TKLDH-----HRGSVTSVK 785
H V C A V+ +L+ +G D+ + I ++ +G L+ L H G VT +
Sbjct: 1125 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1184
Query: 786 VIQDGNIFITGSQDGTVCTWNV 807
DG + I S G + WNV
Sbjct: 1185 FSPDGKMLI--SAGGYIKWWNV 1204
Score = 44.0 bits (99), Expect = 0.004
Identities = 33/146 (22%), Positives = 58/146 (39%), Gaps = 4/146 (2%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
GQ + + Q++ + K+ K H +LC + + +++ T S D V +W+
Sbjct: 627 GQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNS 686
Query: 724 HTLAVKTKILEHIAPVLCVAAIVNRS---LVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
T + EH V C N S L+ +G D + + L + H S
Sbjct: 687 MTGELVHTYDEHSEQVNC-CHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNS 745
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWN 806
V + D + + S DGT+ W+
Sbjct: 746 VNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 42.3 bits (95), Expect = 0.012
Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 9/147 (6%)
Query: 988 GLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYK 1047
G V+VW + T + H G + S + S S D+T +W P +
Sbjct: 1065 GTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELR 1124
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH---------SATGPSASIDVT 1098
GH+ ++ D + D + +W V +G +LH +AT D+
Sbjct: 1125 GHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLC 1184
Query: 1099 LNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+ +L ++ W++ G++S+
Sbjct: 1185 FSPDGKMLISAGGYIKWWNVVTGESSQ 1211
Score = 41.9 bits (94), Expect = 0.016
Identities = 51/261 (19%), Positives = 100/261 (38%), Gaps = 19/261 (7%)
Query: 918 LAAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRD 977
+ A + V +F T+D + + T + E S+ + S
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSH 712
Query: 978 GQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL 1037
L A+G + +++W L+ + T+ GH + FSP++ L+ S S D T+ +W
Sbjct: 713 HLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDA 772
Query: 1038 --ADNSPSLTYK-----------GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIV 1084
A+ S+ K ++ +DG R M + + + + SG++
Sbjct: 773 TSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFAIHTSGLL 832
Query: 1085 LHSATGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFA 1141
TG ++I D + AV++ V +W+ D R H +
Sbjct: 833 GEIHTGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCR---GHLSWVHGVM 889
Query: 1142 LTADSQHVVTGSMDMSLKVWK 1162
+ D +T S D ++++W+
Sbjct: 890 FSPDGSSFLTSSDDQTIRLWE 910
Score = 41.1 bits (92), Expect = 0.028
Identities = 47/231 (20%), Positives = 93/231 (40%), Gaps = 17/231 (7%)
Query: 682 MSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLC 741
++N + H+ ++ C + + Q + + D ++ V+ T +I H VLC
Sbjct: 603 ITNLSCLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLC 662
Query: 742 VAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN--IFITGSQD 799
A + + + D V I + + G LV D H V + + TGS D
Sbjct: 663 CAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSD 722
Query: 800 GTVCTWNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGT------ 852
+ W++ +T+ ++ + D+ L + D L L +
Sbjct: 723 CFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSIN 782
Query: 853 ----YLH---PLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
+L+ P + + VKC + D +R+ V A +I+L+++H++ LL
Sbjct: 783 VKQFFLNLEDPQEDMEVIVKCCSWSADGARIMV-AAKNKIFLFAIHTSGLL 832
Score = 41.1 bits (92), Expect = 0.028
Identities = 40/199 (20%), Positives = 79/199 (39%), Gaps = 7/199 (3%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVI 719
L+P Q++ G ++ +++N + H ++ + T + + L++ S+D +
Sbjct: 969 LSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQ 1028
Query: 720 VWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRG 779
VW+ K L + ++ S ++S D V + +++ G H+G
Sbjct: 1029 VWNWQ--LDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1086
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV---TAGVPIHIFDVTDDNVFLLT 836
+V S + D F + S D T W+ + L + V F V D+ L T
Sbjct: 1087 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSV--DSTLLAT 1144
Query: 837 LQGDNELHLRTFITGTYLH 855
+ E+ + G LH
Sbjct: 1145 GDDNGEIRIWNVSNGELLH 1163
Score = 33.5 bits (73), Expect = 5.7
Identities = 17/73 (23%), Positives = 35/73 (47%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+P V+A S +LW+ S SKV +GH + + + + LT S+D ++ +
Sbjct: 849 SPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRL 908
Query: 721 WDLHTLAVKTKIL 733
W+ + + ++
Sbjct: 909 WETKKVCKNSAVM 921
>AK223195-1|BAD96915.1| 315|Homo sapiens mitogen-activated protein
kinase organizer 1 variant protein.
Length = 315
Score = 67.3 bits (157), Expect = 4e-10
Identities = 62/239 (25%), Positives = 103/239 (43%), Gaps = 7/239 (2%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R ++ G + + S +LW+ + + + T+ GH +L + ++ L +G D
Sbjct: 29 RAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSGGGD 88
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVD--GALVTK 773
+V++WD+ + V K H V V ++++SG DS++ V
Sbjct: 89 KAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPVQT 148
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVF 833
LD R V+SVKV+ D I + GS DG V +++ L S G PI + D
Sbjct: 149 LDEARDGVSSVKVL-DHEI-LAGSVDGRVRRYDLRMGQLFSDY-VGSPITCTCFSRDGQC 205
Query: 834 LLTLQGDNELHLRTFITGTYLHPLKRHK-AKVKCFCVAHDSSRVAVGCA-DQRIYLYSL 890
L D+ L L TG L K HK + K C + V C+ D +++ + L
Sbjct: 206 TLVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCCLSERDTHVVSCSEDGKVFFWDL 264
Score = 58.8 bits (136), Expect = 1e-07
Identities = 72/288 (25%), Positives = 116/288 (40%), Gaps = 17/288 (5%)
Query: 994 QLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
+L RL+ TL+ G + V F+ + L+ D+T+ +W + TY GH +
Sbjct: 12 ELPQKRLK-TLDCGQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEV 70
Query: 1054 QTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLSDG--D 1110
D S + V +W V SG V+ G + ++ V N + V+ G D
Sbjct: 71 LDAAGSFDNSSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSID 130
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
+S+R W + +++ A D + ++ GS+D ++ + L G+L
Sbjct: 131 SSIRCWDCR--SRRPEPVQTLDEARDGVSSVKVLDHE-ILAGSVDGRVRRYDLRMGQLFS 187
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINT---XXXXXXXXXXXXKVTCVKV 1227
VG +TC S + +VS S D L + D +T K+ C
Sbjct: 188 DYVGSP--ITCTCFSRDGQCTLVS-SLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCCLS 244
Query: 1228 TGDGTIAVSCAEDKTLIIWETKRG---LALTSFSLHVPLLGFQITSDC 1272
D T VSC+ED + W+ G LAL S V L + T C
Sbjct: 245 ERD-THVVSCSEDGKVFFWDLVEGALALALPVGSDVVQSLAYHPTEPC 291
Score = 56.0 bits (129), Expect = 9e-07
Identities = 53/224 (23%), Positives = 93/224 (41%), Gaps = 15/224 (6%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
+++W L T +GH + S +N + SG D+ VV+W +A ++GH
Sbjct: 49 LKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSGGGDKAVVLWDVASGQVVRKFRGH 108
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSG-----IVLHSATGPSASIDVTLNMKYA 1104
+ + T+ + +S ++ W S L A +S+ V + +
Sbjct: 109 AGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPVQTLDEARDGVSSVKV---LDHE 165
Query: 1105 VLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKL 1163
+L+ D VR + L G D S ITC + D Q + S+D +L++
Sbjct: 166 ILAGSVDGRVRRYDLRMGQLFSDYVGS-----PITCTCFSRDGQCTLVSSLDSTLRLLDK 220
Query: 1164 DGGKLSQVLVGHSDIVTCVAVSITNK-TQVVSGSWDCNLIVWDI 1206
D G+L GH + + ++ + T VVS S D + WD+
Sbjct: 221 DTGELLGEYKGHKNQEYKLDCCLSERDTHVVSCSEDGKVFFWDL 264
Score = 53.6 bits (123), Expect = 5e-06
Identities = 29/125 (23%), Positives = 57/125 (45%)
Query: 682 MSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLC 741
+ ++ T G++ + + Y LT D ++ +W+ + H VL
Sbjct: 13 LPQKRLKTLDCGQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLD 72
Query: 742 VAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGT 801
A + S + SGG D AV++ + G +V K H G V +V+ ++ + ++GS D +
Sbjct: 73 AAGSFDNSSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSS 132
Query: 802 VCTWN 806
+ W+
Sbjct: 133 IRCWD 137
Score = 45.2 bits (102), Expect = 0.002
Identities = 50/230 (21%), Positives = 92/230 (40%), Gaps = 8/230 (3%)
Query: 975 SRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVV 1034
S D SG V +W +++ ++ GH G + V F+ ++LSGS D ++
Sbjct: 76 SFDNSSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRC 135
Query: 1035 WQLADNSPS--LTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG-P 1091
W P T + ++ ++ A S D V + + G + G P
Sbjct: 136 WDCRSRRPEPVQTLDEARDGVSSVKVLDHEILAGSVD--GRVRRYDLRMGQLFSDYVGSP 193
Query: 1092 SASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVT 1151
+ + + ++S D+++R+ G+ + + + ++ C L+ HVV+
Sbjct: 194 ITCTCFSRDGQCTLVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDC-CLSERDTHVVS 252
Query: 1152 GSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNK--TQVVSGSWDC 1199
S D + W L G L+ L SD+V +A T + GS C
Sbjct: 253 CSEDGKVFFWDLVEGALALALPVGSDVVQSLAYHPTEPCLLTAMGGSVQC 302
Score = 41.9 bits (94), Expect = 0.016
Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 3/121 (2%)
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTD--DN 831
LD +G+V +V+ DGN +T D T+ WN TLL T +G + D DN
Sbjct: 21 LDCGQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTY-SGHGYEVLDAAGSFDN 79
Query: 832 VFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLH 891
L + GD + L +G + + H KV +++ + G D I +
Sbjct: 80 SSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCR 139
Query: 892 S 892
S
Sbjct: 140 S 140
Score = 36.3 bits (80), Expect = 0.81
Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGH---ITCVTFSPNNLLVL 1024
PI+C SRDGQ +R+ T L GH + C S + V+
Sbjct: 193 PITCTCFSRDGQCTLVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDC-CLSERDTHVV 251
Query: 1025 SGSEDRTVVVWQLADNSPSLTYKGHSSAIQTL 1056
S SED V W L + + +L S +Q+L
Sbjct: 252 SCSEDGKVFFWDLVEGALALALPVGSDVVQSL 283
>AK074217-1|BAB85020.1| 506|Homo sapiens protein ( Homo sapiens
cDNA FLJ23637 fis, clone CAS09287. ).
Length = 506
Score = 67.3 bits (157), Expect = 4e-10
Identities = 50/217 (23%), Positives = 91/217 (41%), Gaps = 1/217 (0%)
Query: 683 SNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCV 742
S + TF + C ++ + L+ GSED V ++D+ A + H V V
Sbjct: 69 SQEPIKTFSRFKDTAYCATFRQDGRLLVAGSEDGGVQLFDISGRAPLRQFEGHTKAVHTV 128
Query: 743 AAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQ-DGNIFITGSQDGT 801
+ ++ V+SG DD V + + + + H V + + ++FITGS D T
Sbjct: 129 DSTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFITGSYDHT 188
Query: 802 VCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHK 861
V ++ + +V G P+ + L++ G G L LK H
Sbjct: 189 VKMFDARTSESVLSVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHH 248
Query: 862 AKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
V C C++ R+ G D+++ +YS S +++ +
Sbjct: 249 KTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHS 285
Score = 59.3 bits (137), Expect = 1e-07
Identities = 44/200 (22%), Positives = 89/200 (44%), Gaps = 4/200 (2%)
Query: 971 CLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDR 1030
C +DG+L +G G V+++ +S GH + V + + V+SG++D
Sbjct: 85 CATFRQDGRLLVAGSEDGGVQLFDISGRAPLRQFEGHTKAVHTVDSTADKYHVVSGADDY 144
Query: 1031 TVVVWQLADNSPSLTYKGHSSAIQT-LLMMSDGRRAMSSDRARNVHVW-LVDSGIVLHSA 1088
TV +W + ++ LT+K HS ++ + ++ V ++ S VL
Sbjct: 145 TVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFITGSYDHTVKMFDARTSESVLSVE 204
Query: 1089 TGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQH 1148
G + ++S G V++W + G + + +H + +TC L++ Q
Sbjct: 205 HGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLK--NHHKTVTCLCLSSSGQR 262
Query: 1149 VVTGSMDMSLKVWKLDGGKL 1168
+++GS+D +KV+ K+
Sbjct: 263 LLSGSLDRKVKVYSTTSYKV 282
Score = 55.6 bits (128), Expect = 1e-06
Identities = 50/228 (21%), Positives = 100/228 (43%), Gaps = 11/228 (4%)
Query: 1013 CVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRAR 1072
C TF + L+++GSED V ++ ++ +P ++GH+ A+ T+ +D +S
Sbjct: 85 CATFRQDGRLLVAGSEDGGVQLFDISGRAPLRQFEGHTKAVHTVDSTADKYHVVSGADDY 144
Query: 1073 NVHVWLVDSGIVLHSATGPSASIDV----TLNMKYAVLSDGDNSVRIWSLAGGDNSEDNR 1128
V +W + + + + S + LN + D++V+++ + ++
Sbjct: 145 TVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFITGSYDHTVKMFDA----RTSESV 200
Query: 1129 RSVSHAERITCFALTADSQHVVTGSMDMSLKVW-KLDGGKLSQVLVGHSDIVTCVAVSIT 1187
SV H + + L S ++ + +KVW L GG+L L H VTC+ +S +
Sbjct: 201 LSVEHGQPVES-VLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSS 259
Query: 1188 NKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAV 1235
+ +++SGS D + V+ + ++ D TI V
Sbjct: 260 GQ-RLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALAHEDETIVV 306
Score = 53.6 bits (123), Expect = 5e-06
Identities = 44/180 (24%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Query: 1105 VLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLD 1164
V D V+++ ++G R+ H + + TAD HVV+G+ D ++K+W +
Sbjct: 96 VAGSEDGGVQLFDISG---RAPLRQFEGHTKAVHTVDSTADKYHVVSGADDYTVKLWDIP 152
Query: 1165 GGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTC 1224
K HSD V C S N ++GS+D + ++D T V
Sbjct: 153 NSKEILTFKEHSDYVRCGCASKLNPDLFITGSYDHTVKMFDART-SESVLSVEHGQPVES 211
Query: 1225 VKVTGDGTIAVSCAEDKTLIIWETKRG--LALTSFSLHVPLLGFQITSDCARVVVHLLDR 1282
V + G + VS A + + +W+ +G L ++ + H + ++S R++ LDR
Sbjct: 212 VLLFPSGGLLVS-AGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDR 270
Score = 49.6 bits (113), Expect = 8e-05
Identities = 46/219 (21%), Positives = 94/219 (42%), Gaps = 6/219 (2%)
Query: 664 GQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL 723
G+ LV G QL+ I + + F+GH+ ++ + T + ++++G++D +V +WD+
Sbjct: 92 GRLLVAGSEDGGVQLFDISGRAPLRQFEGHTKAVHTVDSTADKYHVVSGADDYTVKLWDI 151
Query: 724 HTLAVKTKILEHIAPVLC-VAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
EH V C A+ +N L I+G D V + V ++H + V
Sbjct: 152 PNSKEILTFKEHSDYVRCGCASKLNPDLFITGSYDHTVKMFDARTSESVLSVEHGQ-PVE 210
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNV--ENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGD 840
SV + G + ++ V W++ L+S + ++ LL+ D
Sbjct: 211 SVLLFPSGGLLVSAG-GRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLD 269
Query: 841 NELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVG 879
++ + + + +H + A + +AH+ + VG
Sbjct: 270 RKVKVYSTTSYKVVHSFD-YAASILSLALAHEDETIVVG 307
Score = 33.5 bits (73), Expect = 5.7
Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 4/83 (4%)
Query: 954 TNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHIT 1012
T+ ++L E P+ + + G L S R V+VW L +L +L H +T
Sbjct: 196 TSESVLSVEHGQ--PVESVLLFPSGGLLVSAGGR-YVKVWDMLKGGQLLVSLKNHHKTVT 252
Query: 1013 CVTFSPNNLLVLSGSEDRTVVVW 1035
C+ S + +LSGS DR V V+
Sbjct: 253 CLCLSSSGQRLLSGSLDRKVKVY 275
>BC005870-1|AAH05870.1| 315|Homo sapiens mitogen-activated protein
kinase organizer 1 protein.
Length = 315
Score = 66.5 bits (155), Expect = 7e-10
Identities = 62/239 (25%), Positives = 102/239 (42%), Gaps = 7/239 (2%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSED 715
R ++ G + + S +LW+ + + + T+ GH +L + ++ L +G D
Sbjct: 29 RAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSGGGD 88
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVD--GALVTK 773
+V++WD+ + V K H V V ++++SG DS++ V
Sbjct: 89 KAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPVQT 148
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVF 833
LD R V+SVKV D I + GS DG V +++ L S G PI + D
Sbjct: 149 LDEARDGVSSVKV-SDHEI-LAGSVDGRVRRYDLRMGQLFSDY-VGSPITCTCFSRDGQC 205
Query: 834 LLTLQGDNELHLRTFITGTYLHPLKRHK-AKVKCFCVAHDSSRVAVGCA-DQRIYLYSL 890
L D+ L L TG L K HK + K C + V C+ D +++ + L
Sbjct: 206 TLVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCCLSERDTHVVSCSEDGKVFFWDL 264
Score = 60.1 bits (139), Expect = 6e-08
Identities = 72/288 (25%), Positives = 117/288 (40%), Gaps = 17/288 (5%)
Query: 994 QLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
+L RL+ TL+ G + V F+ + L+ D+T+ +W + TY GH +
Sbjct: 12 ELPQKRLK-TLDCGQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEV 70
Query: 1054 QTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKYAVLSDG--D 1110
D S + V +W V SG V+ G + ++ V N + V+ G D
Sbjct: 71 LDAAGSFDNSSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSID 130
Query: 1111 NSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQ 1170
+S+R W + +++ A R ++ ++ GS+D ++ + L G+L
Sbjct: 131 SSIRCWDCR--SRRPEPVQTLDEA-RDGVSSVKVSDHEILAGSVDGRVRRYDLRMGQLFS 187
Query: 1171 VLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINT---XXXXXXXXXXXXKVTCVKV 1227
VG +TC S + +VS S D L + D +T K+ C
Sbjct: 188 DYVGSP--ITCTCFSRDGQCTLVS-SLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCCLS 244
Query: 1228 TGDGTIAVSCAEDKTLIIWETKRG---LALTSFSLHVPLLGFQITSDC 1272
D T VSC+ED + W+ G LAL S V L + T C
Sbjct: 245 ERD-THVVSCSEDGKVFFWDLVEGALALALPVGSGVVQSLAYHPTEPC 291
Score = 55.6 bits (128), Expect = 1e-06
Identities = 53/224 (23%), Positives = 93/224 (41%), Gaps = 15/224 (6%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
+++W L T +GH + S +N + SG D+ VV+W +A ++GH
Sbjct: 49 LKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSGGGDKAVVLWDVASGQVVRKFRGH 108
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSG-----IVLHSATGPSASIDVTLNMKYA 1104
+ + T+ + +S ++ W S L A +S+ V+ +
Sbjct: 109 AGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPVQTLDEARDGVSSVKVS---DHE 165
Query: 1105 VLSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKL 1163
+L+ D VR + L G D S ITC + D Q + S+D +L++
Sbjct: 166 ILAGSVDGRVRRYDLRMGQLFSDYVGS-----PITCTCFSRDGQCTLVSSLDSTLRLLDK 220
Query: 1164 DGGKLSQVLVGHSDIVTCVAVSITNK-TQVVSGSWDCNLIVWDI 1206
D G+L GH + + ++ + T VVS S D + WD+
Sbjct: 221 DTGELLGEYKGHKNQEYKLDCCLSERDTHVVSCSEDGKVFFWDL 264
Score = 53.6 bits (123), Expect = 5e-06
Identities = 29/125 (23%), Positives = 57/125 (45%)
Query: 682 MSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLC 741
+ ++ T G++ + + Y LT D ++ +W+ + H VL
Sbjct: 13 LPQKRLKTLDCGQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLD 72
Query: 742 VAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGT 801
A + S + SGG D AV++ + G +V K H G V +V+ ++ + ++GS D +
Sbjct: 73 AAGSFDNSSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSS 132
Query: 802 VCTWN 806
+ W+
Sbjct: 133 IRCWD 137
Score = 41.9 bits (94), Expect = 0.016
Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 3/121 (2%)
Query: 774 LDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTD--DN 831
LD +G+V +V+ DGN +T D T+ WN TLL T +G + D DN
Sbjct: 21 LDCGQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTY-SGHGYEVLDAAGSFDN 79
Query: 832 VFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLH 891
L + GD + L +G + + H KV +++ + G D I +
Sbjct: 80 SSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCR 139
Query: 892 S 892
S
Sbjct: 140 S 140
Score = 41.5 bits (93), Expect = 0.021
Identities = 45/228 (19%), Positives = 86/228 (37%), Gaps = 4/228 (1%)
Query: 975 SRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVV 1034
S D SG V +W +++ ++ GH G + V F+ ++LSGS D ++
Sbjct: 76 SFDNSSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRC 135
Query: 1035 WQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG-PSA 1093
W P + + ++ V + + G + G P
Sbjct: 136 WDCRSRRPEPVQTLDEARDGVSSVKVSDHEILAGSVDGRVRRYDLRMGQLFSDYVGSPIT 195
Query: 1094 SIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGS 1153
+ + + ++S D+++R+ G+ + + + ++ C L+ HVV+ S
Sbjct: 196 CTCFSRDGQCTLVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDC-CLSERDTHVVSCS 254
Query: 1154 MDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNK--TQVVSGSWDC 1199
D + W L G L+ L S +V +A T + GS C
Sbjct: 255 EDGKVFFWDLVEGALALALPVGSGVVQSLAYHPTEPCLLTAMGGSVQC 302
Score = 36.3 bits (80), Expect = 0.81
Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGH---ITCVTFSPNNLLVL 1024
PI+C SRDGQ +R+ T L GH + C S + V+
Sbjct: 193 PITCTCFSRDGQCTLVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDC-CLSERDTHVV 251
Query: 1025 SGSEDRTVVVWQLADNSPSLTYKGHSSAIQTL 1056
S SED V W L + + +L S +Q+L
Sbjct: 252 SCSEDGKVFFWDLVEGALALALPVGSGVVQSL 283
Score = 33.9 bits (74), Expect = 4.3
Identities = 32/124 (25%), Positives = 53/124 (42%), Gaps = 4/124 (3%)
Query: 690 FKGHSGS-ILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
F + GS I C C +R+ Q L S D+++ + D T + + H + ++
Sbjct: 186 FSDYVGSPITCTCFSRDGQCTLVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCCLSE 245
Query: 749 --SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
+ V+S +D V LV+GAL L G V S+ +T + G+V W
Sbjct: 246 RDTHVVSCSEDGKVFFWDLVEGALALALPVGSGVVQSLAYHPTEPCLLT-AMGGSVQCWR 304
Query: 807 VENF 810
E +
Sbjct: 305 EEAY 308
>BT009800-1|AAP88802.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 66.1 bits (154), Expect = 9e-10
Identities = 50/213 (23%), Positives = 89/213 (41%), Gaps = 12/213 (5%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
++ L+ H G+++C F +N +V S S D T +W + + GH+ +L +
Sbjct: 134 KVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAV 192
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NMKYAVLSDGDNSVRI 1115
D +S + +W V G + TG + I+ N + D S R+
Sbjct: 193 SPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRL 252
Query: 1116 WSLAGGDNSEDNRRSVSHAE---RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+ L ++ SH IT A + + + G D + VW + +L
Sbjct: 253 FDL----RADQELICFSHESIICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGIL 308
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 309 SGHDNRVSCLGVT-ADGMAVATGSWDSFLKIWN 340
Score = 66.1 bits (154), Expect = 9e-10
Identities = 45/177 (25%), Positives = 77/177 (43%), Gaps = 12/177 (6%)
Query: 992 VWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
+W + T + + GH G + SP+ L +SG+ D + +W + + + T+ GH S
Sbjct: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 1052 AIQTLLMMSDGRRAM--SSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSD 1108
I + +G S D + + D ++ S SI V ++ +L
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGRLLFA 287
Query: 1109 G--DNSVRIWSLAGGDNSEDNRRSV--SHAERITCFALTADSQHVVTGSMDMSLKVW 1161
G D + +W D+ + R + H R++C +TAD V TGS D LK+W
Sbjct: 288 GYDDFNCNVW-----DSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 57.6 bits (133), Expect = 3e-07
Identities = 54/214 (25%), Positives = 87/214 (40%), Gaps = 8/214 (3%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +IVWD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D NI +T S D T
Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG--DNELHLRTFITGTYLHPLKRHKA 862
W++E TV G + F L + G D L GT H++
Sbjct: 169 WDIET-GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 863 KVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
+ C + + G D L+ L + Q L
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQEL 261
Score = 57.6 bits (133), Expect = 3e-07
Identities = 63/291 (21%), Positives = 112/291 (38%), Gaps = 16/291 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + + D +L S G + VW +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNFVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMS---DGRRAMSSDRARNVHVWLVDS 1081
G D ++ L ++ SA L D ++S +W +++
Sbjct: 114 CGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIET 173
Query: 1082 G---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERIT 1138
G V TG S+ V+ + + D S ++W + G + H I
Sbjct: 174 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQT---FTGHESDIN 230
Query: 1139 CFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVSG 1195
+ + + TGS D S +++ L + + H I+ T VA S++ + + +G
Sbjct: 231 AICFFPNGEAICTGSDDASCRLFDLRADQ-ELICFSHESIICSITSVAFSLSGRL-LFAG 288
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
D N VWD +V+C+ VT DG + + D L IW
Sbjct: 289 YDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 54.8 bits (126), Expect = 2e-06
Identities = 50/236 (21%), Positives = 95/236 (40%), Gaps = 8/236 (3%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMS---NSKV-HTFKGHSGSILCMCVTRESQYLLTGSEDT 716
APSG + ++++ S N KV H+G + C C + ++T S DT
Sbjct: 106 APSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSC-CRFLDDNNIVTSSGDT 164
Query: 717 SVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
+ +WD+ T KT + H + +A + +L ISG D++ + + +G
Sbjct: 165 TCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTG 224
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NFTLLSTVTAGVPIHIFDVTDDNVFLL 835
H + ++ +G TGS D + +++ + L+ + I V L
Sbjct: 225 HESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGRL 284
Query: 836 TLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
G ++ + + + + L H +V C V D VA G D + +++
Sbjct: 285 LFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 52.0 bits (119), Expect = 2e-05
Identities = 37/161 (22%), Positives = 66/161 (40%), Gaps = 5/161 (3%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
A + LV A G +W + +KVH S ++ ++ G D +
Sbjct: 64 ATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSI 123
Query: 721 WDLHT----LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
++L + + V ++ H + C + + ++V S GD + + + G T
Sbjct: 124 YNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCAL-WDIETGQQKTVFVG 182
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
H G S+ V D N+FI+G+ D + W+V T T T
Sbjct: 183 HTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFT 223
Score = 52.0 bits (119), Expect = 2e-05
Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L ++P + +LW + + TF GH I +C + + TGS+D S
Sbjct: 190 LAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDAS 249
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + H I + VA ++ L+ +G DD + + V L
Sbjct: 250 CRLFDLRA-DQELICFSHESIICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGIL 308
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 309 SGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 50.8 bits (116), Expect = 4e-05
Identities = 42/218 (19%), Positives = 92/218 (42%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D + +S+ + + VW + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
+ DN I++L + N + +R +H ++C D ++VT S D + +
Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFL-DDNNIVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ G+ V VGH+ +AVS + +SG+ D + +WD+
Sbjct: 169 WDIETGQQKTVFVGHTGDCMSLAVS-PDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D + +++ + L FS
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS 265
Score = 41.9 bits (94), Expect = 0.016
Identities = 32/151 (21%), Positives = 61/151 (40%), Gaps = 5/151 (3%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRT 1031
L VS D L SG ++W + + T GH I + F PN + +GS+D +
Sbjct: 190 LAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDAS 249
Query: 1032 VVVWQLADNSPSLTYKGHS--SAIQTLLMMSDGRRAMSSDRARNVHVW--LVDSGI-VLH 1086
++ L + + + S +I ++ GR + N +VW + + +L
Sbjct: 250 CRLFDLRADQELICFSHESIICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILS 309
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
+ + VT + D+ ++IW+
Sbjct: 310 GHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>BC002454-1|AAH02454.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 66.1 bits (154), Expect = 9e-10
Identities = 50/213 (23%), Positives = 89/213 (41%), Gaps = 12/213 (5%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
++ L+ H G+++C F +N +V S S D T +W + + GH+ +L +
Sbjct: 134 KVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAV 192
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NMKYAVLSDGDNSVRI 1115
D +S + +W V G + TG + I+ N + D S R+
Sbjct: 193 SPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRL 252
Query: 1116 WSLAGGDNSEDNRRSVSHAE---RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+ L ++ SH IT A + + + G D + VW + +L
Sbjct: 253 FDL----RADQELICFSHESIICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGIL 308
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 309 SGHDNRVSCLGVT-ADGMAVATGSWDSFLKIWN 340
Score = 66.1 bits (154), Expect = 9e-10
Identities = 45/177 (25%), Positives = 77/177 (43%), Gaps = 12/177 (6%)
Query: 992 VWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
+W + T + + GH G + SP+ L +SG+ D + +W + + + T+ GH S
Sbjct: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 1052 AIQTLLMMSDGRRAM--SSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSD 1108
I + +G S D + + D ++ S SI V ++ +L
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGRLLFA 287
Query: 1109 G--DNSVRIWSLAGGDNSEDNRRSV--SHAERITCFALTADSQHVVTGSMDMSLKVW 1161
G D + +W D+ + R + H R++C +TAD V TGS D LK+W
Sbjct: 288 GYDDFNCNVW-----DSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 57.6 bits (133), Expect = 3e-07
Identities = 54/214 (25%), Positives = 87/214 (40%), Gaps = 8/214 (3%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +IVWD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D NI +T S D T
Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG--DNELHLRTFITGTYLHPLKRHKA 862
W++E TV G + F L + G D L GT H++
Sbjct: 169 WDIET-GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 863 KVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
+ C + + G D L+ L + Q L
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQEL 261
Score = 57.6 bits (133), Expect = 3e-07
Identities = 63/291 (21%), Positives = 112/291 (38%), Gaps = 16/291 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + + D +L S G + VW +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNFVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMS---DGRRAMSSDRARNVHVWLVDS 1081
G D ++ L ++ SA L D ++S +W +++
Sbjct: 114 CGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIET 173
Query: 1082 G---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERIT 1138
G V TG S+ V+ + + D S ++W + G + H I
Sbjct: 174 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQT---FTGHESDIN 230
Query: 1139 CFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVSG 1195
+ + + TGS D S +++ L + + H I+ T VA S++ + + +G
Sbjct: 231 AICFFPNGEAICTGSDDASCRLFDLRADQ-ELICFSHESIICSITSVAFSLSGRL-LFAG 288
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
D N VWD +V+C+ VT DG + + D L IW
Sbjct: 289 YDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 54.8 bits (126), Expect = 2e-06
Identities = 50/236 (21%), Positives = 95/236 (40%), Gaps = 8/236 (3%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMS---NSKV-HTFKGHSGSILCMCVTRESQYLLTGSEDT 716
APSG + ++++ S N KV H+G + C C + ++T S DT
Sbjct: 106 APSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSC-CRFLDDNNIVTSSGDT 164
Query: 717 SVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
+ +WD+ T KT + H + +A + +L ISG D++ + + +G
Sbjct: 165 TCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTG 224
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NFTLLSTVTAGVPIHIFDVTDDNVFLL 835
H + ++ +G TGS D + +++ + L+ + I V L
Sbjct: 225 HESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGRL 284
Query: 836 TLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
G ++ + + + + L H +V C V D VA G D + +++
Sbjct: 285 LFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 52.0 bits (119), Expect = 2e-05
Identities = 37/161 (22%), Positives = 66/161 (40%), Gaps = 5/161 (3%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
A + LV A G +W + +KVH S ++ ++ G D +
Sbjct: 64 ATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSI 123
Query: 721 WDLHT----LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
++L + + V ++ H + C + + ++V S GD + + + G T
Sbjct: 124 YNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCAL-WDIETGQQKTVFVG 182
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
H G S+ V D N+FI+G+ D + W+V T T T
Sbjct: 183 HTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFT 223
Score = 52.0 bits (119), Expect = 2e-05
Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L ++P + +LW + + TF GH I +C + + TGS+D S
Sbjct: 190 LAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDAS 249
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + H I + VA ++ L+ +G DD + + V L
Sbjct: 250 CRLFDLRA-DQELICFSHESIICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGIL 308
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 309 SGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 50.8 bits (116), Expect = 4e-05
Identities = 42/218 (19%), Positives = 92/218 (42%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D + +S+ + + VW + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
+ DN I++L + N + +R +H ++C D ++VT S D + +
Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFL-DDNNIVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ G+ V VGH+ +AVS + +SG+ D + +WD+
Sbjct: 169 WDIETGQQKTVFVGHTGDCMSLAVS-PDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D + +++ + L FS
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS 265
Score = 41.9 bits (94), Expect = 0.016
Identities = 32/151 (21%), Positives = 61/151 (40%), Gaps = 5/151 (3%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRT 1031
L VS D L SG ++W + + T GH I + F PN + +GS+D +
Sbjct: 190 LAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDAS 249
Query: 1032 VVVWQLADNSPSLTYKGHS--SAIQTLLMMSDGRRAMSSDRARNVHVW--LVDSGI-VLH 1086
++ L + + + S +I ++ GR + N +VW + + +L
Sbjct: 250 CRLFDLRADQELICFSHESIICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILS 309
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
+ + VT + D+ ++IW+
Sbjct: 310 GHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>BC000115-1|AAH00115.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 66.1 bits (154), Expect = 9e-10
Identities = 50/213 (23%), Positives = 89/213 (41%), Gaps = 12/213 (5%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
++ L+ H G+++C F +N +V S S D T +W + + GH+ +L +
Sbjct: 134 KVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAV 192
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NMKYAVLSDGDNSVRI 1115
D +S + +W V G + TG + I+ N + D S R+
Sbjct: 193 SPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRL 252
Query: 1116 WSLAGGDNSEDNRRSVSHAE---RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+ L ++ SH IT A + + + G D + VW + +L
Sbjct: 253 FDL----RADQELICFSHESIICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGIL 308
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 309 SGHDNRVSCLGVT-ADGMAVATGSWDSFLKIWN 340
Score = 66.1 bits (154), Expect = 9e-10
Identities = 45/177 (25%), Positives = 77/177 (43%), Gaps = 12/177 (6%)
Query: 992 VWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
+W + T + + GH G + SP+ L +SG+ D + +W + + + T+ GH S
Sbjct: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 1052 AIQTLLMMSDGRRAM--SSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSD 1108
I + +G S D + + D ++ S SI V ++ +L
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGRLLFA 287
Query: 1109 G--DNSVRIWSLAGGDNSEDNRRSV--SHAERITCFALTADSQHVVTGSMDMSLKVW 1161
G D + +W D+ + R + H R++C +TAD V TGS D LK+W
Sbjct: 288 GYDDFNCNVW-----DSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 57.6 bits (133), Expect = 3e-07
Identities = 54/214 (25%), Positives = 87/214 (40%), Gaps = 8/214 (3%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +IVWD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D NI +T S D T
Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG--DNELHLRTFITGTYLHPLKRHKA 862
W++E TV G + F L + G D L GT H++
Sbjct: 169 WDIET-GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 863 KVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
+ C + + G D L+ L + Q L
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQEL 261
Score = 57.6 bits (133), Expect = 3e-07
Identities = 63/291 (21%), Positives = 112/291 (38%), Gaps = 16/291 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + + D +L S G + VW +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNFVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMS---DGRRAMSSDRARNVHVWLVDS 1081
G D ++ L ++ SA L D ++S +W +++
Sbjct: 114 CGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIET 173
Query: 1082 G---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERIT 1138
G V TG S+ V+ + + D S ++W + G + H I
Sbjct: 174 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQT---FTGHESDIN 230
Query: 1139 CFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVSG 1195
+ + + TGS D S +++ L + + H I+ T VA S++ + + +G
Sbjct: 231 AICFFPNGEAICTGSDDASCRLFDLRADQ-ELICFSHESIICSITSVAFSLSGRL-LFAG 288
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
D N VWD +V+C+ VT DG + + D L IW
Sbjct: 289 YDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 54.8 bits (126), Expect = 2e-06
Identities = 50/236 (21%), Positives = 95/236 (40%), Gaps = 8/236 (3%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMS---NSKV-HTFKGHSGSILCMCVTRESQYLLTGSEDT 716
APSG + ++++ S N KV H+G + C C + ++T S DT
Sbjct: 106 APSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSC-CRFLDDNNIVTSSGDT 164
Query: 717 SVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
+ +WD+ T KT + H + +A + +L ISG D++ + + +G
Sbjct: 165 TCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTG 224
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NFTLLSTVTAGVPIHIFDVTDDNVFLL 835
H + ++ +G TGS D + +++ + L+ + I V L
Sbjct: 225 HESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGRL 284
Query: 836 TLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
G ++ + + + + L H +V C V D VA G D + +++
Sbjct: 285 LFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 52.0 bits (119), Expect = 2e-05
Identities = 37/161 (22%), Positives = 66/161 (40%), Gaps = 5/161 (3%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
A + LV A G +W + +KVH S ++ ++ G D +
Sbjct: 64 ATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSI 123
Query: 721 WDLHT----LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
++L + + V ++ H + C + + ++V S GD + + + G T
Sbjct: 124 YNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCAL-WDIETGQQKTVFVG 182
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
H G S+ V D N+FI+G+ D + W+V T T T
Sbjct: 183 HTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFT 223
Score = 52.0 bits (119), Expect = 2e-05
Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L ++P + +LW + + TF GH I +C + + TGS+D S
Sbjct: 190 LAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDAS 249
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + H I + VA ++ L+ +G DD + + V L
Sbjct: 250 CRLFDLRA-DQELICFSHESIICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGIL 308
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 309 SGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 50.8 bits (116), Expect = 4e-05
Identities = 42/218 (19%), Positives = 92/218 (42%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D + +S+ + + VW + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
+ DN I++L + N + +R +H ++C D ++VT S D + +
Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFL-DDNNIVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ G+ V VGH+ +AVS + +SG+ D + +WD+
Sbjct: 169 WDIETGQQKTVFVGHTGDCMSLAVS-PDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D + +++ + L FS
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS 265
Score = 41.9 bits (94), Expect = 0.016
Identities = 32/151 (21%), Positives = 61/151 (40%), Gaps = 5/151 (3%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRT 1031
L VS D L SG ++W + + T GH I + F PN + +GS+D +
Sbjct: 190 LAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDAS 249
Query: 1032 VVVWQLADNSPSLTYKGHS--SAIQTLLMMSDGRRAMSSDRARNVHVW--LVDSGI-VLH 1086
++ L + + + S +I ++ GR + N +VW + + +L
Sbjct: 250 CRLFDLRADQELICFSHESIICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILS 309
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
+ + VT + D+ ++IW+
Sbjct: 310 GHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>Y12050-1|CAA72779.1| 340|Homo sapiens guanine nucleotide-binding
protein beta3 subunit protein.
Length = 340
Score = 65.7 bits (153), Expect = 1e-09
Identities = 50/213 (23%), Positives = 89/213 (41%), Gaps = 12/213 (5%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
++ L+ H G+++C F +N +V S S D T +W + + GH+ +L +
Sbjct: 134 KVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAV 192
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NMKYAVLSDGDNSVRI 1115
D +S + +W V G + TG + I+ N + D S R+
Sbjct: 193 SPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRL 252
Query: 1116 WSLAGGDNSEDNRRSVSHAE---RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+ L ++ SH IT A + + + G D + VW + +L
Sbjct: 253 FDL----RADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGIL 308
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 309 SGHDNRVSCLGVT-ADGMAVATGSWDSFLKIWN 340
Score = 64.5 bits (150), Expect = 3e-09
Identities = 44/177 (24%), Positives = 76/177 (42%), Gaps = 12/177 (6%)
Query: 992 VWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
+W + T + + GH G + SP+ L +SG+ D + +W + + + T+ GH S
Sbjct: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 1052 AIQTLLMMSDGRRAM--SSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSD 1108
I + +G S D + + D ++ S I V ++ +L
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFA 287
Query: 1109 G--DNSVRIWSLAGGDNSEDNRRSV--SHAERITCFALTADSQHVVTGSMDMSLKVW 1161
G D + +W D+ + R + H R++C +TAD V TGS D LK+W
Sbjct: 288 GYDDFNCNVW-----DSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 57.6 bits (133), Expect = 3e-07
Identities = 54/214 (25%), Positives = 87/214 (40%), Gaps = 8/214 (3%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +IVWD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D NI +T S D T
Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG--DNELHLRTFITGTYLHPLKRHKA 862
W++E TV G + F L + G D L GT H++
Sbjct: 169 WDIET-GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 863 KVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
+ C + + G D L+ L + Q L
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQEL 261
Score = 57.6 bits (133), Expect = 3e-07
Identities = 63/291 (21%), Positives = 112/291 (38%), Gaps = 16/291 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + + D +L S G + VW +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNFVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMS---DGRRAMSSDRARNVHVWLVDS 1081
G D ++ L ++ SA L D ++S +W +++
Sbjct: 114 CGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIET 173
Query: 1082 G---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERIT 1138
G V TG S+ V+ + + D S ++W + G + H I
Sbjct: 174 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQT---FTGHESDIN 230
Query: 1139 CFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVSG 1195
+ + + TGS D S +++ L + + H I+ T VA S++ + + +G
Sbjct: 231 AICFFPNGEAICTGSDDASCRLFDLRADQ-ELICFSHESIICGITSVAFSLSGRL-LFAG 288
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
D N VWD +V+C+ VT DG + + D L IW
Sbjct: 289 YDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 54.4 bits (125), Expect = 3e-06
Identities = 50/236 (21%), Positives = 95/236 (40%), Gaps = 8/236 (3%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMS---NSKV-HTFKGHSGSILCMCVTRESQYLLTGSEDT 716
APSG + ++++ S N KV H+G + C C + ++T S DT
Sbjct: 106 APSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSC-CRFLDDNNIVTSSGDT 164
Query: 717 SVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
+ +WD+ T KT + H + +A + +L ISG D++ + + +G
Sbjct: 165 TCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTG 224
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NFTLLSTVTAGVPIHIFDVTDDNVFLL 835
H + ++ +G TGS D + +++ + L+ + I V L
Sbjct: 225 HESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRL 284
Query: 836 TLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
G ++ + + + + L H +V C V D VA G D + +++
Sbjct: 285 LFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 52.0 bits (119), Expect = 2e-05
Identities = 37/161 (22%), Positives = 66/161 (40%), Gaps = 5/161 (3%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
A + LV A G +W + +KVH S ++ ++ G D +
Sbjct: 64 ATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSI 123
Query: 721 WDLHT----LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
++L + + V ++ H + C + + ++V S GD + + + G T
Sbjct: 124 YNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCAL-WDIETGQQKTVFVG 182
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
H G S+ V D N+FI+G+ D + W+V T T T
Sbjct: 183 HTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFT 223
Score = 51.6 bits (118), Expect = 2e-05
Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L ++P + +LW + + TF GH I +C + + TGS+D S
Sbjct: 190 LAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDAS 249
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + H I + VA ++ L+ +G DD + + V L
Sbjct: 250 CRLFDLRA-DQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGIL 308
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 309 SGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 50.8 bits (116), Expect = 4e-05
Identities = 42/218 (19%), Positives = 92/218 (42%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D + +S+ + + VW + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
+ DN I++L + N + +R +H ++C D ++VT S D + +
Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFL-DDNNIVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ G+ V VGH+ +AVS + +SG+ D + +WD+
Sbjct: 169 WDIETGQQKTVFVGHTGDCMSLAVS-PDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D + +++ + L FS
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS 265
Score = 41.5 bits (93), Expect = 0.021
Identities = 32/151 (21%), Positives = 60/151 (39%), Gaps = 5/151 (3%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRT 1031
L VS D L SG ++W + + T GH I + F PN + +GS+D +
Sbjct: 190 LAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDAS 249
Query: 1032 VVVWQLADNSPSLTYKGHS--SAIQTLLMMSDGRRAMSSDRARNVHVW--LVDSGI-VLH 1086
++ L + + + S I ++ GR + N +VW + + +L
Sbjct: 250 CRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILS 309
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
+ + VT + D+ ++IW+
Sbjct: 310 GHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>U47924-5|AAB51313.1| 340|Homo sapiens G-protein beta-3 chain
protein.
Length = 340
Score = 65.7 bits (153), Expect = 1e-09
Identities = 50/213 (23%), Positives = 89/213 (41%), Gaps = 12/213 (5%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
++ L+ H G+++C F +N +V S S D T +W + + GH+ +L +
Sbjct: 134 KVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAV 192
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NMKYAVLSDGDNSVRI 1115
D +S + +W V G + TG + I+ N + D S R+
Sbjct: 193 SPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRL 252
Query: 1116 WSLAGGDNSEDNRRSVSHAE---RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+ L ++ SH IT A + + + G D + VW + +L
Sbjct: 253 FDL----RADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGIL 308
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 309 SGHDNRVSCLGVT-ADGMAVATGSWDSFLKIWN 340
Score = 64.5 bits (150), Expect = 3e-09
Identities = 44/177 (24%), Positives = 76/177 (42%), Gaps = 12/177 (6%)
Query: 992 VWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
+W + T + + GH G + SP+ L +SG+ D + +W + + + T+ GH S
Sbjct: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 1052 AIQTLLMMSDGRRAM--SSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSD 1108
I + +G S D + + D ++ S I V ++ +L
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFA 287
Query: 1109 G--DNSVRIWSLAGGDNSEDNRRSV--SHAERITCFALTADSQHVVTGSMDMSLKVW 1161
G D + +W D+ + R + H R++C +TAD V TGS D LK+W
Sbjct: 288 GYDDFNCNVW-----DSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 57.6 bits (133), Expect = 3e-07
Identities = 54/214 (25%), Positives = 87/214 (40%), Gaps = 8/214 (3%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +IVWD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D NI +T S D T
Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG--DNELHLRTFITGTYLHPLKRHKA 862
W++E TV G + F L + G D L GT H++
Sbjct: 169 WDIET-GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 863 KVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
+ C + + G D L+ L + Q L
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQEL 261
Score = 57.6 bits (133), Expect = 3e-07
Identities = 63/291 (21%), Positives = 112/291 (38%), Gaps = 16/291 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + + D +L S G + VW +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNFVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMS---DGRRAMSSDRARNVHVWLVDS 1081
G D ++ L ++ SA L D ++S +W +++
Sbjct: 114 CGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIET 173
Query: 1082 G---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERIT 1138
G V TG S+ V+ + + D S ++W + G + H I
Sbjct: 174 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQT---FTGHESDIN 230
Query: 1139 CFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVSG 1195
+ + + TGS D S +++ L + + H I+ T VA S++ + + +G
Sbjct: 231 AICFFPNGEAICTGSDDASCRLFDLRADQ-ELICFSHESIICGITSVAFSLSGRL-LFAG 288
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
D N VWD +V+C+ VT DG + + D L IW
Sbjct: 289 YDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 54.4 bits (125), Expect = 3e-06
Identities = 50/236 (21%), Positives = 95/236 (40%), Gaps = 8/236 (3%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMS---NSKV-HTFKGHSGSILCMCVTRESQYLLTGSEDT 716
APSG + ++++ S N KV H+G + C C + ++T S DT
Sbjct: 106 APSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSC-CRFLDDNNIVTSSGDT 164
Query: 717 SVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
+ +WD+ T KT + H + +A + +L ISG D++ + + +G
Sbjct: 165 TCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTG 224
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NFTLLSTVTAGVPIHIFDVTDDNVFLL 835
H + ++ +G TGS D + +++ + L+ + I V L
Sbjct: 225 HESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRL 284
Query: 836 TLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
G ++ + + + + L H +V C V D VA G D + +++
Sbjct: 285 LFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 52.0 bits (119), Expect = 2e-05
Identities = 37/161 (22%), Positives = 66/161 (40%), Gaps = 5/161 (3%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
A + LV A G +W + +KVH S ++ ++ G D +
Sbjct: 64 ATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSI 123
Query: 721 WDLHT----LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
++L + + V ++ H + C + + ++V S GD + + + G T
Sbjct: 124 YNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCAL-WDIETGQQKTVFVG 182
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
H G S+ V D N+FI+G+ D + W+V T T T
Sbjct: 183 HTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFT 223
Score = 51.6 bits (118), Expect = 2e-05
Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L ++P + +LW + + TF GH I +C + + TGS+D S
Sbjct: 190 LAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDAS 249
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + H I + VA ++ L+ +G DD + + V L
Sbjct: 250 CRLFDLRA-DQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGIL 308
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 309 SGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 50.8 bits (116), Expect = 4e-05
Identities = 42/218 (19%), Positives = 92/218 (42%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D + +S+ + + VW + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
+ DN I++L + N + +R +H ++C D ++VT S D + +
Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFL-DDNNIVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ G+ V VGH+ +AVS + +SG+ D + +WD+
Sbjct: 169 WDIETGQQKTVFVGHTGDCMSLAVS-PDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D + +++ + L FS
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS 265
Score = 41.5 bits (93), Expect = 0.021
Identities = 32/151 (21%), Positives = 60/151 (39%), Gaps = 5/151 (3%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRT 1031
L VS D L SG ++W + + T GH I + F PN + +GS+D +
Sbjct: 190 LAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDAS 249
Query: 1032 VVVWQLADNSPSLTYKGHS--SAIQTLLMMSDGRRAMSSDRARNVHVW--LVDSGI-VLH 1086
++ L + + + S I ++ GR + N +VW + + +L
Sbjct: 250 CRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILS 309
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
+ + VT + D+ ++IW+
Sbjct: 310 GHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>M31328-1|AAA52582.1| 340|Homo sapiens GNB3 protein.
Length = 340
Score = 65.7 bits (153), Expect = 1e-09
Identities = 50/213 (23%), Positives = 89/213 (41%), Gaps = 12/213 (5%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
++ L+ H G+++C F +N +V S S D T +W + + GH+ +L +
Sbjct: 134 KVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAV 192
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NMKYAVLSDGDNSVRI 1115
D +S + +W V G + TG + I+ N + D S R+
Sbjct: 193 SPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRL 252
Query: 1116 WSLAGGDNSEDNRRSVSHAE---RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+ L ++ SH IT A + + + G D + VW + +L
Sbjct: 253 FDL----RADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGIL 308
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 309 SGHDNRVSCLGVT-ADGMAVATGSWDSFLKIWN 340
Score = 64.5 bits (150), Expect = 3e-09
Identities = 44/177 (24%), Positives = 76/177 (42%), Gaps = 12/177 (6%)
Query: 992 VWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
+W + T + + GH G + SP+ L +SG+ D + +W + + + T+ GH S
Sbjct: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 1052 AIQTLLMMSDGRRAM--SSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSD 1108
I + +G S D + + D ++ S I V ++ +L
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFA 287
Query: 1109 G--DNSVRIWSLAGGDNSEDNRRSV--SHAERITCFALTADSQHVVTGSMDMSLKVW 1161
G D + +W D+ + R + H R++C +TAD V TGS D LK+W
Sbjct: 288 GYDDFNCNVW-----DSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 57.6 bits (133), Expect = 3e-07
Identities = 54/214 (25%), Positives = 87/214 (40%), Gaps = 8/214 (3%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +IVWD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D NI +T S D T
Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG--DNELHLRTFITGTYLHPLKRHKA 862
W++E TV G + F L + G D L GT H++
Sbjct: 169 WDIET-GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 863 KVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
+ C + + G D L+ L + Q L
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQEL 261
Score = 57.6 bits (133), Expect = 3e-07
Identities = 63/291 (21%), Positives = 112/291 (38%), Gaps = 16/291 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + + D +L S G + VW +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNFVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMS---DGRRAMSSDRARNVHVWLVDS 1081
G D ++ L ++ SA L D ++S +W +++
Sbjct: 114 CGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIET 173
Query: 1082 G---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERIT 1138
G V TG S+ V+ + + D S ++W + G + H I
Sbjct: 174 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQT---FTGHESDIN 230
Query: 1139 CFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVSG 1195
+ + + TGS D S +++ L + + H I+ T VA S++ + + +G
Sbjct: 231 AICFFPNGEAICTGSDDASCRLFDLRADQ-ELICFSHESIICGITSVAFSLSGRL-LFAG 288
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
D N VWD +V+C+ VT DG + + D L IW
Sbjct: 289 YDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 54.4 bits (125), Expect = 3e-06
Identities = 50/236 (21%), Positives = 95/236 (40%), Gaps = 8/236 (3%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMS---NSKV-HTFKGHSGSILCMCVTRESQYLLTGSEDT 716
APSG + ++++ S N KV H+G + C C + ++T S DT
Sbjct: 106 APSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSC-CRFLDDNNIVTSSGDT 164
Query: 717 SVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
+ +WD+ T KT + H + +A + +L ISG D++ + + +G
Sbjct: 165 TCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTG 224
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NFTLLSTVTAGVPIHIFDVTDDNVFLL 835
H + ++ +G TGS D + +++ + L+ + I V L
Sbjct: 225 HESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRL 284
Query: 836 TLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
G ++ + + + + L H +V C V D VA G D + +++
Sbjct: 285 LFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 52.0 bits (119), Expect = 2e-05
Identities = 37/161 (22%), Positives = 66/161 (40%), Gaps = 5/161 (3%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
A + LV A G +W + +KVH S ++ ++ G D +
Sbjct: 64 ATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSI 123
Query: 721 WDLHT----LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
++L + + V ++ H + C + + ++V S GD + + + G T
Sbjct: 124 YNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCAL-WDIETGQQKTVFVG 182
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
H G S+ V D N+FI+G+ D + W+V T T T
Sbjct: 183 HTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFT 223
Score = 51.6 bits (118), Expect = 2e-05
Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L ++P + +LW + + TF GH I +C + + TGS+D S
Sbjct: 190 LAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDAS 249
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + H I + VA ++ L+ +G DD + + V L
Sbjct: 250 CRLFDLRA-DQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGIL 308
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 309 SGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 50.8 bits (116), Expect = 4e-05
Identities = 42/218 (19%), Positives = 92/218 (42%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D + +S+ + + VW + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
+ DN I++L + N + +R +H ++C D ++VT S D + +
Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFL-DDNNIVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ G+ V VGH+ +AVS + +SG+ D + +WD+
Sbjct: 169 WDIETGQQKTVFVGHTGDCMSLAVS-PDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D + +++ + L FS
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS 265
Score = 41.5 bits (93), Expect = 0.021
Identities = 32/151 (21%), Positives = 60/151 (39%), Gaps = 5/151 (3%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRT 1031
L VS D L SG ++W + + T GH I + F PN + +GS+D +
Sbjct: 190 LAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDAS 249
Query: 1032 VVVWQLADNSPSLTYKGHS--SAIQTLLMMSDGRRAMSSDRARNVHVW--LVDSGI-VLH 1086
++ L + + + S I ++ GR + N +VW + + +L
Sbjct: 250 CRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILS 309
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
+ + VT + D+ ++IW+
Sbjct: 310 GHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>BC114618-1|AAI14619.1| 332|Homo sapiens GNB1 protein protein.
Length = 332
Score = 65.7 bits (153), Expect = 1e-09
Identities = 53/219 (24%), Positives = 95/219 (43%), Gaps = 17/219 (7%)
Query: 978 GQLGASGCARGLVRVWQLSTH----RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
G A G + ++ L T R+ L GH G+++C F +N +V S S D T
Sbjct: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS-SGDTTCA 167
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA 1093
+W + + T+ GH+ + +L + D R +S + +W V G+ + TG +
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227
Query: 1094 SIDVTL----NMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE---RITCFALTADS 1146
I+ +A SD D + R++ L ++ + SH IT + +
Sbjct: 228 DINAICFFPNGNAFATGSD-DATCRLFDL----RADQELMTYSHDNIICGITSVSFSKSG 282
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVS 1185
+ ++ G D + VW + VL GH + V+C+ V+
Sbjct: 283 RLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT 321
Score = 59.3 bits (137), Expect = 1e-07
Identities = 44/189 (23%), Positives = 78/189 (41%), Gaps = 4/189 (2%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH+G + C C + ++T S DT+ +WD+ T T H V+ ++ + L
Sbjct: 141 GHTGYLSC-CRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLF 199
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFT 811
+SG D++ + + +G H + ++ +GN F TGS D T +++
Sbjct: 200 VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 259
Query: 812 LLSTVT-AGVPIHIFDVTDDNVFLLTLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFC 868
L T + + I V+ L L G ++ + + + L H +V C
Sbjct: 260 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLG 319
Query: 869 VAHDSSRVA 877
V D VA
Sbjct: 320 VTDDGMAVA 328
Score = 56.8 bits (131), Expect = 5e-07
Identities = 41/177 (23%), Positives = 79/177 (44%), Gaps = 7/177 (3%)
Query: 669 LAPSAGDPQ--LWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
+ S+GD LW I + + TF GH+G ++ + + +++ ++G+ D S +WD+
Sbjct: 157 IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 727 AVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-VDGALVT-KLDHHRGSVTSV 784
+ H + + + N + +G DD+ + L D L+T D+ +TSV
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSV 276
Query: 785 KVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVP--IHIFDVTDDNVFLLTLQG 839
+ G + + G D W+ + V AG + VTDD + + ++ G
Sbjct: 277 SFSKSGRLLLAGYDDFNCNVWDALKAD-RAGVLAGHDNRVSCLGVTDDGMAVASVLG 332
Score = 56.0 bits (129), Expect = 9e-07
Identities = 50/257 (19%), Positives = 96/257 (37%), Gaps = 12/257 (4%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
R + TL GH+ I + + ++ L++S S+D +++W + SS + T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 1059 MSDGRRAMSS--DRARNVHVWLVDSGIVLHSA--TGPSASIDVT--LNMKYAVLSDGDNS 1112
G D +++ G V S G + + L+ V S GD +
Sbjct: 106 APSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTT 165
Query: 1113 VRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+W + G + H + +L D++ V+G+ D S K+W + G Q
Sbjct: 166 CALWDIETG---QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF 222
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX--KVTCVKVTGD 1230
GH + + N +GS D ++D+ +T V +
Sbjct: 223 TGHESDINAICF-FPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKS 281
Query: 1231 GTIAVSCAEDKTLIIWE 1247
G + ++ +D +W+
Sbjct: 282 GRLLLAGYDDFNCNVWD 298
Score = 54.8 bits (126), Expect = 2e-06
Identities = 50/215 (23%), Positives = 87/215 (40%), Gaps = 6/215 (2%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +I+WD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D I +T S D T
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVTAGV-PIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAK 863
W++E +T T + + D ++ D L G H++
Sbjct: 169 WDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESD 228
Query: 864 VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRT 898
+ C + + A G D L+ L + Q L T
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMT 263
Score = 53.2 bits (122), Expect = 7e-06
Identities = 35/155 (22%), Positives = 62/155 (40%), Gaps = 5/155 (3%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT- 725
LV A G +W + +KVH S ++ Y+ G D +++L T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR 129
Query: 726 ---LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVT 782
+ V ++ H + C + + +V S GD + + + G T H G V
Sbjct: 130 EGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA-LWDIETGQQTTTFTGHTGDVM 188
Query: 783 SVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
S+ + D +F++G+ D + W+V T T
Sbjct: 189 SLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFT 223
Score = 52.4 bits (120), Expect = 1e-05
Identities = 42/188 (22%), Positives = 75/188 (39%), Gaps = 9/188 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+SC D Q+ S +W + T + T GH G + ++ +P+ L +SG+
Sbjct: 146 LSCCRFLDDNQIVTSS-GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRR-AMSSDRAR-NVHVWLVDSGIVLH 1086
D + +W + + T+ GH S I + +G A SD A + D ++ +
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY 264
Query: 1087 SATGPSASI-DVTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALT 1143
S I V+ + +L G D + +W D + H R++C +T
Sbjct: 265 SHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRA---GVLAGHDNRVSCLGVT 321
Query: 1144 ADSQHVVT 1151
D V +
Sbjct: 322 DDGMAVAS 329
Score = 51.2 bits (117), Expect = 3e-05
Identities = 43/219 (19%), Positives = 95/219 (43%), Gaps = 8/219 (3%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D R +S+ + + +W + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
Y DN I++L + N +R H ++C D+Q +VT S D + +
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV-VSGSWDCNLIVWDINTXXXXXXXXXXX 1219
W ++ G+ + GH+ V +++S+ T++ VSG+ D + +WD+
Sbjct: 169 WDIETGQQTTTFTGHTGDV--MSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 1220 XKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D T +++ + L ++S
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS 265
Score = 49.2 bits (112), Expect = 1e-04
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 7/128 (5%)
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKL---DGG-KLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC A +V G +D ++ L +G ++S+ L GH+ ++C N Q+
Sbjct: 101 MTC-AYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN--QI 157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
V+ S D +WDI T V + + D + VS A D + +W+ + G+
Sbjct: 158 VTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGM 217
Query: 1253 ALTSFSLH 1260
+F+ H
Sbjct: 218 CRQTFTGH 225
Score = 45.6 bits (103), Expect = 0.001
Identities = 55/281 (19%), Positives = 106/281 (37%), Gaps = 16/281 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + D +L S G + +W +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNYVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYK----GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
G D ++ L ++ GH+ + + D + SS +W ++
Sbjct: 114 CGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDT-TCALWDIE 172
Query: 1081 SG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
+G TG S+ + + + V D S ++W + G + H I
Sbjct: 173 TGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG---MCRQTFTGHESDI 229
Query: 1138 TCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCV-AVSITNKTQVV-SG 1195
+ TGS D + +++ L + + H +I+ + +VS + +++ +G
Sbjct: 230 NAICFFPNGNAFATGSDDATCRLFDLRADQ-ELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVS 1236
D N VWD +V+C+ VT DG S
Sbjct: 289 YDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVAS 329
Score = 39.1 bits (87), Expect = 0.11
Identities = 32/135 (23%), Positives = 53/135 (39%), Gaps = 2/135 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L LAP + V +LW + TF GH I +C TGS+D +
Sbjct: 190 LSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDAT 249
Query: 718 VIVWDLHT-LAVKTKILEH-IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
++DL + T ++ I + V+ + L+++G DD + + L
Sbjct: 250 CRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLA 309
Query: 776 HHRGSVTSVKVIQDG 790
H V+ + V DG
Sbjct: 310 GHDNRVSCLGVTDDG 324
>AY631872-1|AAT38116.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 65.7 bits (153), Expect = 1e-09
Identities = 50/213 (23%), Positives = 89/213 (41%), Gaps = 12/213 (5%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
++ L+ H G+++C F +N +V S S D T +W + + GH+ +L +
Sbjct: 134 KVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAV 192
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NMKYAVLSDGDNSVRI 1115
D +S + +W V G + TG + I+ N + D S R+
Sbjct: 193 SPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRL 252
Query: 1116 WSLAGGDNSEDNRRSVSHAE---RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+ L ++ SH IT A + + + G D + VW + +L
Sbjct: 253 FDL----RADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGIL 308
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 309 SGHDNRVSCLGVT-ADGMAVATGSWDSFLKIWN 340
Score = 64.5 bits (150), Expect = 3e-09
Identities = 44/177 (24%), Positives = 76/177 (42%), Gaps = 12/177 (6%)
Query: 992 VWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
+W + T + + GH G + SP+ L +SG+ D + +W + + + T+ GH S
Sbjct: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 1052 AIQTLLMMSDGRRAM--SSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSD 1108
I + +G S D + + D ++ S I V ++ +L
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFA 287
Query: 1109 G--DNSVRIWSLAGGDNSEDNRRSV--SHAERITCFALTADSQHVVTGSMDMSLKVW 1161
G D + +W D+ + R + H R++C +TAD V TGS D LK+W
Sbjct: 288 GYDDFNCNVW-----DSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 57.6 bits (133), Expect = 3e-07
Identities = 54/214 (25%), Positives = 87/214 (40%), Gaps = 8/214 (3%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +IVWD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D NI +T S D T
Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG--DNELHLRTFITGTYLHPLKRHKA 862
W++E TV G + F L + G D L GT H++
Sbjct: 169 WDIET-GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 863 KVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
+ C + + G D L+ L + Q L
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQEL 261
Score = 57.6 bits (133), Expect = 3e-07
Identities = 63/291 (21%), Positives = 112/291 (38%), Gaps = 16/291 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + + D +L S G + VW +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNFVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMS---DGRRAMSSDRARNVHVWLVDS 1081
G D ++ L ++ SA L D ++S +W +++
Sbjct: 114 CGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIET 173
Query: 1082 G---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERIT 1138
G V TG S+ V+ + + D S ++W + G + H I
Sbjct: 174 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQT---FTGHESDIN 230
Query: 1139 CFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVSG 1195
+ + + TGS D S +++ L + + H I+ T VA S++ + + +G
Sbjct: 231 AICFFPNGEAICTGSDDASCRLFDLRADQ-ELICFSHESIICGITSVAFSLSGRL-LFAG 288
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
D N VWD +V+C+ VT DG + + D L IW
Sbjct: 289 YDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 54.4 bits (125), Expect = 3e-06
Identities = 50/236 (21%), Positives = 95/236 (40%), Gaps = 8/236 (3%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMS---NSKV-HTFKGHSGSILCMCVTRESQYLLTGSEDT 716
APSG + ++++ S N KV H+G + C C + ++T S DT
Sbjct: 106 APSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSC-CRFLDDNNIVTSSGDT 164
Query: 717 SVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
+ +WD+ T KT + H + +A + +L ISG D++ + + +G
Sbjct: 165 TCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTG 224
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NFTLLSTVTAGVPIHIFDVTDDNVFLL 835
H + ++ +G TGS D + +++ + L+ + I V L
Sbjct: 225 HESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRL 284
Query: 836 TLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
G ++ + + + + L H +V C V D VA G D + +++
Sbjct: 285 LFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 52.0 bits (119), Expect = 2e-05
Identities = 37/161 (22%), Positives = 66/161 (40%), Gaps = 5/161 (3%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
A + LV A G +W + +KVH S ++ ++ G D +
Sbjct: 64 ATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSI 123
Query: 721 WDLHT----LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
++L + + V ++ H + C + + ++V S GD + + + G T
Sbjct: 124 YNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCAL-WDIETGQQKTVFVG 182
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
H G S+ V D N+FI+G+ D + W+V T T T
Sbjct: 183 HTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFT 223
Score = 51.6 bits (118), Expect = 2e-05
Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L ++P + +LW + + TF GH I +C + + TGS+D S
Sbjct: 190 LAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDAS 249
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + H I + VA ++ L+ +G DD + + V L
Sbjct: 250 CRLFDLRA-DQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGIL 308
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 309 SGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 50.8 bits (116), Expect = 4e-05
Identities = 42/218 (19%), Positives = 92/218 (42%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D + +S+ + + VW + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
+ DN I++L + N + +R +H ++C D ++VT S D + +
Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFL-DDNNIVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ G+ V VGH+ +AVS + +SG+ D + +WD+
Sbjct: 169 WDIETGQQKTVFVGHTGDCMSLAVS-PDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D + +++ + L FS
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS 265
Score = 41.5 bits (93), Expect = 0.021
Identities = 32/151 (21%), Positives = 60/151 (39%), Gaps = 5/151 (3%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRT 1031
L VS D L SG ++W + + T GH I + F PN + +GS+D +
Sbjct: 190 LAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDAS 249
Query: 1032 VVVWQLADNSPSLTYKGHS--SAIQTLLMMSDGRRAMSSDRARNVHVW--LVDSGI-VLH 1086
++ L + + + S I ++ GR + N +VW + + +L
Sbjct: 250 CRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILS 309
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
+ + VT + D+ ++IW+
Sbjct: 310 GHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>AY336089-1|AAR24619.1| 271|Homo sapiens proliferation-inducing gene
21 protein.
Length = 271
Score = 65.7 bits (153), Expect = 1e-09
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 10/202 (4%)
Query: 975 SRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPN--NLLVLSGSEDRT 1031
S D + SG +++W L + H ++CV FSPN N +++S D+
Sbjct: 68 SSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL 127
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGP 1091
V VW LA+ + GH+ + T+ + DG S + +W ++ G L++ G
Sbjct: 128 VKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG 187
Query: 1092 SASIDVTLN-MKYAVLSDGDNSVRIWSLAGGDNSEDNRRSV----SHAE--RITCFALTA 1144
+ + +Y + + S++IW L G ++ ++ V S AE + T A +A
Sbjct: 188 DIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSA 247
Query: 1145 DSQHVVTGSMDMSLKVWKLDGG 1166
D Q + G D ++VW++ G
Sbjct: 248 DGQTLFAGYTDNLVRVWQVTIG 269
Score = 60.5 bits (140), Expect = 4e-08
Identities = 34/126 (26%), Positives = 61/126 (48%), Gaps = 2/126 (1%)
Query: 1128 RRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDG-GKLSQVLVGHSDIVTCVAVSI 1186
RR V H + + A ++D++ +V+GS D ++K+W G K + HS+ V+CV S
Sbjct: 53 RRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSP 112
Query: 1187 TNKTQ-VVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLII 1245
+ +VS WD + VW++ + V V+ DG++ S +D ++
Sbjct: 113 NSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAML 172
Query: 1246 WETKRG 1251
W+ G
Sbjct: 173 WDLNEG 178
Score = 57.2 bits (132), Expect = 4e-07
Identities = 38/153 (24%), Positives = 72/153 (47%), Gaps = 3/153 (1%)
Query: 690 FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWD-LHTLAVKTKILEHIAPVLCVAAIVNR 748
F GH+ +L + + +++ +++GS D ++ +W+ L + H V CV N
Sbjct: 55 FVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNS 114
Query: 749 S--LVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
S +++S G D V + +L + L T H G + +V V DG++ +G +DG W+
Sbjct: 115 SNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWD 174
Query: 807 VENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG 839
+ L T+ G I+ + + +L G
Sbjct: 175 LNEGKHLYTLDGGDIINALCFSPNRYWLCAATG 207
Score = 37.9 bits (84), Expect = 0.26
Identities = 49/240 (20%), Positives = 104/240 (43%), Gaps = 23/240 (9%)
Query: 981 GASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQ-LAD 1039
G CA G+ + +T R GH + V FS +N ++SGS D+T+ +W L
Sbjct: 36 GMEPCASGISQRKGTTTRRFV----GHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGV 91
Query: 1040 NSPSLTYKGHSSAIQTLLMM--SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID- 1096
++ + HS + + S +S + V VW + + + + G + ++
Sbjct: 92 CKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNT 151
Query: 1097 VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSM 1154
VT++ ++ + G D +W L N + ++ + I + +++ + +
Sbjct: 152 VTVSPDGSLCASGGKDGQAMLWDL----NEGKHLYTLDGGDIINALCF-SPNRYWLCAAT 206
Query: 1155 DMSLKVWKLDG----GKLSQVLVGHS---DIVTCVAVSITNKTQVVSGSWDCNLI-VWDI 1206
S+K+W L+G +L Q ++ S + C +++ + Q + + NL+ VW +
Sbjct: 207 GPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 266
Score = 35.5 bits (78), Expect = 1.4
Identities = 33/122 (27%), Positives = 51/122 (41%), Gaps = 9/122 (7%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNN--LLVLSG 1026
++ + VS DG L ASG G +W L+ + TL+G I + FSPN L +G
Sbjct: 149 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DIINALCFSPNRYWLCAATG 207
Query: 1027 SE------DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVD 1080
+ ++V +L S + K +L +DG+ + V VW V
Sbjct: 208 PSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 267
Query: 1081 SG 1082
G
Sbjct: 268 IG 269
>AK131444-1|BAD18589.1| 472|Homo sapiens protein ( Homo sapiens cDNA
FLJ16579 fis, clone TESTI2049956, weakly similar to
Vegetatible incompatibility protein HET-E-1. ).
Length = 472
Score = 65.7 bits (153), Expect = 1e-09
Identities = 56/226 (24%), Positives = 100/226 (44%), Gaps = 11/226 (4%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE-DRTVVVWQLAD-NSPSLTYK 1047
VR W L T +L + ++C FSP+ V+SG + D + + + + S+
Sbjct: 169 VRAWDLETGKLLWKVRYDTFIVSC-KFSPDGKYVVSGFDVDHGICIMDAENITTVSVIKD 227
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSAT-GPSASID---VTLNMKY 1103
H+ +I + D +R S R + +W V S L + T S +I T + +
Sbjct: 228 HHTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGHF 287
Query: 1104 AVLSDGDNSVRIWSLAGGDNSEDNRRSV---SHAERITCFALTADSQHVVTGSMDMSLKV 1160
S D +++IW++ G+ H ++ DS +++G D ++ +
Sbjct: 288 LCTSSWDKNLKIWNVHTGEFRNRGACVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAI 347
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
W + G L GH+D V VA+S NK ++S S D + +W+I
Sbjct: 348 WDVAEGYRKLSLKGHNDWVMDVAIS-NNKKWILSASKDRTMRLWNI 392
Score = 65.3 bits (152), Expect = 2e-09
Identities = 59/267 (22%), Positives = 109/267 (40%), Gaps = 12/267 (4%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSA-IQTLLMMSDG 1062
L+GH ++ F ++ +LSGS D TV +W D S ++ A + + D
Sbjct: 98 LSGHEHAVSTCHFCVDDTKLLSGSYDCTVKLWDPVDGSVVRDFEHRPKAPVVECSITGDS 157
Query: 1063 RRAMSSDRARNVHVWLVDSGIVLHSATGPS--ASIDVTLNMKYAVLSDGDNSVRIWSLAG 1120
R +++ + V W +++G +L + S + + KY V+S D I +
Sbjct: 158 SRVIAASYDKTVRAWDLETGKLLWKVRYDTFIVSCKFSPDGKY-VVSGFDVDHGICIMDA 216
Query: 1121 GDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDG-GKLSQVLVGHSDIV 1179
+ + + H IT DSQ V + S+D +K+W + L + HS+ +
Sbjct: 217 ENITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAI 276
Query: 1180 TCVAVSITNKTQVVSGSWDCNLIVWDINT------XXXXXXXXXXXXKVTCVKVTGDGTI 1233
+ + + + + SWD NL +W+++T V+ D +
Sbjct: 277 SNCCFTFSGHF-LCTSSWDKNLKIWNVHTGEFRNRGACVTLMQGHEGSVSSCHFARDSSF 335
Query: 1234 AVSCAEDKTLIIWETKRGLALTSFSLH 1260
+S D+T+ IW+ G S H
Sbjct: 336 LISGGFDRTVAIWDVAEGYRKLSLKGH 362
Score = 63.3 bits (147), Expect = 6e-09
Identities = 69/300 (23%), Positives = 122/300 (40%), Gaps = 23/300 (7%)
Query: 746 VNRSLVISGGDDSAVIITSLVDGALVTKLDHH-RGSVTSVKVIQDGNIFITGSQDGTVCT 804
V+ + ++SG D V + VDG++V +H + V + D + I S D TV
Sbjct: 112 VDDTKLLSGSYDCTVKLWDPVDGSVVRDFEHRPKAPVVECSITGDSSRVIAASYDKTVRA 171
Query: 805 WNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT-LQGDNELHLRTFITGTYLHPLKRHKAK 863
W++E LL V I + D ++++ D+ + + T + +K H +
Sbjct: 172 WDLETGKLLWKVRYDTFIVSCKFSPDGKYVVSGFDVDHGICIMDAENITTVSVIKDHHTR 231
Query: 864 -VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXX--XXXXXXFLLAA 920
+ C DS RVA D+ I ++ + S L T FL +
Sbjct: 232 SITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFLCTS 291
Query: 921 GGNR-VTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQ 979
++ + I++ HT + FR +TL+Q + +S +RD
Sbjct: 292 SWDKNLKIWNVHTGE----FR----------NRGACVTLMQGHEGS---VSSCHFARDSS 334
Query: 980 LGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLAD 1039
SG V +W ++ + +L GH + V S N +LS S+DRT+ +W + +
Sbjct: 335 FLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAISNNKKWILSASKDRTMRLWNIEE 394
Score = 58.4 bits (135), Expect = 2e-07
Identities = 39/139 (28%), Positives = 63/139 (45%), Gaps = 7/139 (5%)
Query: 677 QLWHIMSNSKVHTF-KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL------AVK 729
++W + S + + T K HS +I C T +L T S D ++ +W++HT A
Sbjct: 255 KIWDVTSQATLLTITKAHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNRGACV 314
Query: 730 TKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQD 789
T + H V + S +ISGG D V I + +G L H V V + +
Sbjct: 315 TLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAISNN 374
Query: 790 GNIFITGSQDGTVCTWNVE 808
++ S+D T+ WN+E
Sbjct: 375 KKWILSASKDRTMRLWNIE 393
Score = 52.4 bits (120), Expect = 1e-05
Identities = 56/225 (24%), Positives = 94/225 (41%), Gaps = 12/225 (5%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMC-VTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEH 735
+LW + S V F+ + + C +T +S ++ S D +V WDL T + K+
Sbjct: 127 KLWDPVDGSVVRDFEHRPKAPVVECSITGDSSRVIAASYDKTVRAWDLETGKLLWKVRYD 186
Query: 736 IAPVLCVAAIVNRSLVISGGD-DSAVIITSLVDGALVTKL-DHHRGSVTSVKVIQDGNIF 793
V C + + V+SG D D + I + V+ + DHH S+TS D
Sbjct: 187 TFIVSCKFS-PDGKYVVSGFDVDHGICIMDAENITTVSVIKDHHTRSITSCCFDPDSQRV 245
Query: 794 ITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFD--VTDDNVFLLTLQGDNELHLRTFITG 851
+ S D + W+V + L T+T I + T FL T D L + TG
Sbjct: 246 ASVSLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTG 305
Query: 852 TYLHP------LKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ + ++ H+ V A DSS + G D+ + ++ +
Sbjct: 306 EFRNRGACVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDV 350
Score = 52.0 bits (119), Expect = 2e-05
Identities = 30/137 (21%), Positives = 66/137 (48%), Gaps = 9/137 (6%)
Query: 950 TKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ------AT 1003
T T +T+ +A S+ I C S G + +++W + T +
Sbjct: 260 TSQATLLTITKAH-SNAISNCCFTFS--GHFLCTSSWDKNLKIWNVHTGEFRNRGACVTL 316
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR 1063
+ GH G ++ F+ ++ ++SG DRTV +W +A+ L+ KGH+ + + + ++ +
Sbjct: 317 MQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAISNNKK 376
Query: 1064 RAMSSDRARNVHVWLVD 1080
+S+ + R + +W ++
Sbjct: 377 WILSASKDRTMRLWNIE 393
Score = 46.4 bits (105), Expect = 8e-04
Identities = 40/161 (24%), Positives = 68/161 (42%), Gaps = 8/161 (4%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVL--CVAAIVNRSL 750
H+ SI C +SQ + + S D + +WD+ + A I + + + C L
Sbjct: 229 HTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFL 288
Query: 751 VISGGDDSAVIITSLVD-----GALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
S D + I GA VT + H GSV+S +D + I+G D TV W
Sbjct: 289 CTSSWDKNLKIWNVHTGEFRNRGACVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIW 348
Query: 806 NV-ENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHL 845
+V E + LS + ++++ ++L+ D + L
Sbjct: 349 DVAEGYRKLSLKGHNDWVMDVAISNNKKWILSASKDRTMRL 389
Score = 45.2 bits (102), Expect = 0.002
Identities = 51/209 (24%), Positives = 87/209 (41%), Gaps = 12/209 (5%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEH--IAPVLCVAAIVNRSL 750
H+ S CV + LL+GS D +V +WD +V + EH APV+ + + S
Sbjct: 103 HAVSTCHFCV--DDTKLLSGSYDCTVKLWDPVDGSV-VRDFEHRPKAPVVECSITGDSSR 159
Query: 751 VISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG-SQDGTVCTWNVEN 809
VI+ D V L G L+ K+ + + S K DG ++G D +C + EN
Sbjct: 160 VIAASYDKTVRAWDLETGKLLWKV-RYDTFIVSCKFSPDGKYVVSGFDVDHGICIMDAEN 218
Query: 810 FTLLSTV----TAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVK 865
T +S + T + FD V ++L ++ T T L K H +
Sbjct: 219 ITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDVT-SQATLLTITKAHSNAIS 277
Query: 866 CFCVAHDSSRVAVGCADQRIYLYSLHSAQ 894
C + D+ + ++++H+ +
Sbjct: 278 NCCFTFSGHFLCTSSWDKNLKIWNVHTGE 306
>AF501884-1|AAM15920.1| 340|Homo sapiens guanine nucleotide binding
protein beta 3 protein.
Length = 340
Score = 65.7 bits (153), Expect = 1e-09
Identities = 50/213 (23%), Positives = 89/213 (41%), Gaps = 12/213 (5%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
++ L+ H G+++C F +N +V S S D T +W + + GH+ +L +
Sbjct: 134 KVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAV 192
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NMKYAVLSDGDNSVRI 1115
D +S + +W V G + TG + I+ N + D S R+
Sbjct: 193 SPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRL 252
Query: 1116 WSLAGGDNSEDNRRSVSHAE---RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+ L ++ SH IT A + + + G D + VW + +L
Sbjct: 253 FDL----RADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGIL 308
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 309 SGHDNRVSCLGVT-ADGMAVATGSWDSFLKIWN 340
Score = 64.5 bits (150), Expect = 3e-09
Identities = 44/177 (24%), Positives = 76/177 (42%), Gaps = 12/177 (6%)
Query: 992 VWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
+W + T + + GH G + SP+ L +SG+ D + +W + + + T+ GH S
Sbjct: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 1052 AIQTLLMMSDGRRAM--SSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSD 1108
I + +G S D + + D ++ S I V ++ +L
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFA 287
Query: 1109 G--DNSVRIWSLAGGDNSEDNRRSV--SHAERITCFALTADSQHVVTGSMDMSLKVW 1161
G D + +W D+ + R + H R++C +TAD V TGS D LK+W
Sbjct: 288 GYDDFNCNVW-----DSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 57.6 bits (133), Expect = 3e-07
Identities = 54/214 (25%), Positives = 87/214 (40%), Gaps = 8/214 (3%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +IVWD +T I + V+ A +
Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D NI +T S D T
Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNI-VTSSGDTTCAL 168
Query: 805 WNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG--DNELHLRTFITGTYLHPLKRHKA 862
W++E TV G + F L + G D L GT H++
Sbjct: 169 WDIET-GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 863 KVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
+ C + + G D L+ L + Q L
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQEL 261
Score = 57.6 bits (133), Expect = 3e-07
Identities = 63/291 (21%), Positives = 112/291 (38%), Gaps = 16/291 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + + D +L S G + VW +T+++ A +TC ++P+ V
Sbjct: 55 LAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNFVA 113
Query: 1025 SGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMS---DGRRAMSSDRARNVHVWLVDS 1081
G D ++ L ++ SA L D ++S +W +++
Sbjct: 114 CGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIET 173
Query: 1082 G---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERIT 1138
G V TG S+ V+ + + D S ++W + G + H I
Sbjct: 174 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQT---FTGHESDIN 230
Query: 1139 CFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVSG 1195
+ + + TGS D S +++ L + + H I+ T VA S++ + + +G
Sbjct: 231 AICFFPNGEAICTGSDDASCRLFDLRADQ-ELICFSHESIICGITSVAFSLSGRL-LFAG 288
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
D N VWD +V+C+ VT DG + + D L IW
Sbjct: 289 YDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 54.4 bits (125), Expect = 3e-06
Identities = 50/236 (21%), Positives = 95/236 (40%), Gaps = 8/236 (3%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMS---NSKV-HTFKGHSGSILCMCVTRESQYLLTGSEDT 716
APSG + ++++ S N KV H+G + C C + ++T S DT
Sbjct: 106 APSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSC-CRFLDDNNIVTSSGDT 164
Query: 717 SVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
+ +WD+ T KT + H + +A + +L ISG D++ + + +G
Sbjct: 165 TCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTG 224
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NFTLLSTVTAGVPIHIFDVTDDNVFLL 835
H + ++ +G TGS D + +++ + L+ + I V L
Sbjct: 225 HESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRL 284
Query: 836 TLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
G ++ + + + + L H +V C V D VA G D + +++
Sbjct: 285 LFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 52.0 bits (119), Expect = 2e-05
Identities = 37/161 (22%), Positives = 66/161 (40%), Gaps = 5/161 (3%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
A + LV A G +W + +KVH S ++ ++ G D +
Sbjct: 64 ATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSI 123
Query: 721 WDLHT----LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
++L + + V ++ H + C + + ++V S GD + + + G T
Sbjct: 124 YNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCAL-WDIETGQQKTVFVG 182
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
H G S+ V D N+FI+G+ D + W+V T T T
Sbjct: 183 HTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFT 223
Score = 51.6 bits (118), Expect = 2e-05
Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L ++P + +LW + + TF GH I +C + + TGS+D S
Sbjct: 190 LAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDAS 249
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + H I + VA ++ L+ +G DD + + V L
Sbjct: 250 CRLFDLRA-DQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGIL 308
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 309 SGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 50.8 bits (116), Expect = 4e-05
Identities = 42/218 (19%), Positives = 92/218 (42%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D + +S+ + + VW + +H+ S+ + +
Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
+ DN I++L + N + +R +H ++C D ++VT S D + +
Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFL-DDNNIVTSSGDTTCAL 168
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ G+ V VGH+ +AVS + +SG+ D + +WD+
Sbjct: 169 WDIETGQQKTVFVGHTGDCMSLAVS-PDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D + +++ + L FS
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS 265
Score = 41.5 bits (93), Expect = 0.021
Identities = 32/151 (21%), Positives = 60/151 (39%), Gaps = 5/151 (3%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRT 1031
L VS D L SG ++W + + T GH I + F PN + +GS+D +
Sbjct: 190 LAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDAS 249
Query: 1032 VVVWQLADNSPSLTYKGHS--SAIQTLLMMSDGRRAMSSDRARNVHVW--LVDSGI-VLH 1086
++ L + + + S I ++ GR + N +VW + + +L
Sbjct: 250 CRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILS 309
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
+ + VT + D+ ++IW+
Sbjct: 310 GHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>AB209283-1|BAD92520.1| 327|Homo sapiens guanine nucleotide-binding
protein, beta-3 subunit variant protein.
Length = 327
Score = 65.7 bits (153), Expect = 1e-09
Identities = 50/213 (23%), Positives = 89/213 (41%), Gaps = 12/213 (5%)
Query: 999 RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLM 1058
++ L+ H G+++C F +N +V S S D T +W + + GH+ +L +
Sbjct: 121 KVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAV 179
Query: 1059 MSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NMKYAVLSDGDNSVRI 1115
D +S + +W V G + TG + I+ N + D S R+
Sbjct: 180 SPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRL 239
Query: 1116 WSLAGGDNSEDNRRSVSHAE---RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVL 1172
+ L ++ SH IT A + + + G D + VW + +L
Sbjct: 240 FDL----RADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGIL 295
Query: 1173 VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
GH + V+C+ V+ + V +GSWD L +W+
Sbjct: 296 SGHDNRVSCLGVT-ADGMAVATGSWDSFLKIWN 327
Score = 64.5 bits (150), Expect = 3e-09
Identities = 44/177 (24%), Positives = 76/177 (42%), Gaps = 12/177 (6%)
Query: 992 VWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSS 1051
+W + T + + GH G + SP+ L +SG+ D + +W + + + T+ GH S
Sbjct: 155 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 214
Query: 1052 AIQTLLMMSDGRRAM--SSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVLSD 1108
I + +G S D + + D ++ S I V ++ +L
Sbjct: 215 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFA 274
Query: 1109 G--DNSVRIWSLAGGDNSEDNRRSV--SHAERITCFALTADSQHVVTGSMDMSLKVW 1161
G D + +W D+ + R + H R++C +TAD V TGS D LK+W
Sbjct: 275 GYDDFNCNVW-----DSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 326
Score = 57.6 bits (133), Expect = 3e-07
Identities = 54/214 (25%), Positives = 87/214 (40%), Gaps = 8/214 (3%)
Query: 689 TFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNR 748
T +GH I M +S+ L++ S+D +IVWD +T I + V+ A +
Sbjct: 37 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 96
Query: 749 SLVISGGDDSAVIITSLV--DG--ALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCT 804
+ V GG D+ I +L +G + +L H G ++ + + D NI +T S D T
Sbjct: 97 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNI-VTSSGDTTCAL 155
Query: 805 WNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQG--DNELHLRTFITGTYLHPLKRHKA 862
W++E TV G + F L + G D L GT H++
Sbjct: 156 WDIET-GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 214
Query: 863 KVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLL 896
+ C + + G D L+ L + Q L
Sbjct: 215 DINAICFFPNGEAICTGSDDASCRLFDLRADQEL 248
Score = 57.6 bits (133), Expect = 3e-07
Identities = 63/291 (21%), Positives = 112/291 (38%), Gaps = 16/291 (5%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQ-LSTHRLQATLNGHIGHITCVTFSPNNLLVL 1024
L I + + D +L S G + VW +T+++ A +TC ++P+ V
Sbjct: 42 LAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCA-YAPSGNFVA 100
Query: 1025 SGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMS---DGRRAMSSDRARNVHVWLVDS 1081
G D ++ L ++ SA L D ++S +W +++
Sbjct: 101 CGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIET 160
Query: 1082 G---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERIT 1138
G V TG S+ V+ + + D S ++W + G + H I
Sbjct: 161 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQT---FTGHESDIN 217
Query: 1139 CFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV---TCVAVSITNKTQVVSG 1195
+ + + TGS D S +++ L + + H I+ T VA S++ + + +G
Sbjct: 218 AICFFPNGEAICTGSDDASCRLFDLRADQ-ELICFSHESIICGITSVAFSLSGRL-LFAG 275
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
D N VWD +V+C+ VT DG + + D L IW
Sbjct: 276 YDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 326
Score = 54.4 bits (125), Expect = 3e-06
Identities = 50/236 (21%), Positives = 95/236 (40%), Gaps = 8/236 (3%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMS---NSKV-HTFKGHSGSILCMCVTRESQYLLTGSEDT 716
APSG + ++++ S N KV H+G + C C + ++T S DT
Sbjct: 93 APSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSC-CRFLDDNNIVTSSGDT 151
Query: 717 SVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
+ +WD+ T KT + H + +A + +L ISG D++ + + +G
Sbjct: 152 TCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTG 211
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE-NFTLLSTVTAGVPIHIFDVTDDNVFLL 835
H + ++ +G TGS D + +++ + L+ + I V L
Sbjct: 212 HESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRL 271
Query: 836 TLQGDNELHLRTF--ITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
G ++ + + + + L H +V C V D VA G D + +++
Sbjct: 272 LFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 327
Score = 52.0 bits (119), Expect = 2e-05
Identities = 37/161 (22%), Positives = 66/161 (40%), Gaps = 5/161 (3%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
A + LV A G +W + +KVH S ++ ++ G D +
Sbjct: 51 ATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSI 110
Query: 721 WDLHT----LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
++L + + V ++ H + C + + ++V S GD + + + G T
Sbjct: 111 YNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCAL-WDIETGQQKTVFVG 169
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT 817
H G S+ V D N+FI+G+ D + W+V T T T
Sbjct: 170 HTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFT 210
Score = 51.6 bits (118), Expect = 2e-05
Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L ++P + +LW + + TF GH I +C + + TGS+D S
Sbjct: 177 LAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDAS 236
Query: 718 VIVWDLHTLAVKTKILEH---IAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL 774
++DL + H I + VA ++ L+ +G DD + + V L
Sbjct: 237 CRLFDLRA-DQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGIL 295
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
H V+ + V DG TGS D + WN
Sbjct: 296 SGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 327
Score = 50.8 bits (116), Expect = 4e-05
Identities = 42/218 (19%), Positives = 92/218 (42%), Gaps = 6/218 (2%)
Query: 1045 TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL---NM 1101
T +GH + I + +D + +S+ + + VW + +H+ S+ + +
Sbjct: 37 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 96
Query: 1102 KYAVLSDGDNSVRIWSLAGGD-NSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKV 1160
+ DN I++L + N + +R +H ++C D ++VT S D + +
Sbjct: 97 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFL-DDNNIVTSSGDTTCAL 155
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXX 1220
W ++ G+ V VGH+ +AVS + +SG+ D + +WD+
Sbjct: 156 WDIETGQQKTVFVGHTGDCMSLAVS-PDFNLFISGACDASAKLWDVREGTCRQTFTGHES 214
Query: 1221 KVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFS 1258
+ + +G + ++D + +++ + L FS
Sbjct: 215 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS 252
Score = 41.5 bits (93), Expect = 0.021
Identities = 32/151 (21%), Positives = 60/151 (39%), Gaps = 5/151 (3%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRT 1031
L VS D L SG ++W + + T GH I + F PN + +GS+D +
Sbjct: 177 LAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDAS 236
Query: 1032 VVVWQLADNSPSLTYKGHS--SAIQTLLMMSDGRRAMSSDRARNVHVW--LVDSGI-VLH 1086
++ L + + + S I ++ GR + N +VW + + +L
Sbjct: 237 CRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILS 296
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWS 1117
+ + VT + D+ ++IW+
Sbjct: 297 GHDNRVSCLGVTADGMAVATGSWDSFLKIWN 327
>BC111490-1|AAI11491.1| 768|Homo sapiens BRWD3 protein protein.
Length = 768
Score = 65.3 bits (152), Expect = 2e-09
Identities = 76/341 (22%), Positives = 137/341 (40%), Gaps = 35/341 (10%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLS 1025
L + C+ R G+ +G LV++W RL ATL GH I+ + + N L+ +
Sbjct: 180 LSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAA 239
Query: 1026 GSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR---RAMSSDRARNV------HV 1076
GS D+ V VW L +P +GHS++I ++ + R ++S A HV
Sbjct: 240 GSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHV 299
Query: 1077 WLV---DSGIVLHSATGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
+ D + + P I + + D+ +RI+ L G + E
Sbjct: 300 KTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYL-GSEVPEKIAEL 358
Query: 1131 VSHAERITC--FALTADSQHVVTGSMDMSLKVWKLDGGKLSQV-------LVGHS----- 1176
SH +++ F DS V+GS D + ++W+ + + + G++
Sbjct: 359 ESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMTGNNLPSGE 418
Query: 1177 DIVTCVAVSIT----NKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV-TGDG 1231
D +T + V++ T V++ + L VW+ T +V ++ D
Sbjct: 419 DKITKLKVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQ 478
Query: 1232 TIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLGFQITSDC 1272
I +S D + IW+ RG + ++ + G DC
Sbjct: 479 RIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDC 519
Score = 57.2 bits (132), Expect = 4e-07
Identities = 57/242 (23%), Positives = 99/242 (40%), Gaps = 23/242 (9%)
Query: 983 SGCAR-GLVRVWQLSTH-RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN 1040
+GC+R G + H ++ + GH+ + CV F + + +GS+D V +W D
Sbjct: 153 TGCSRFGHIFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDG 212
Query: 1041 SPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI----- 1095
T +GHS+ I + + + + + V VW + + + G SASI
Sbjct: 213 RLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQF 272
Query: 1096 --DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAER------ITCFALTADSQ 1147
+Y + D ++ W + R V ER I+C + ++
Sbjct: 273 CPSTKGTNRYLTSTGADGTICFWQW-HVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGM 331
Query: 1148 HVVTGSMDMSLKVWKLDGGKLSQV--LVGHSDIVTCVAVSITN---KTQVVSGSWDCNLI 1202
+ TGS D ++++ L ++ L H+D V VAV N + VSGS D
Sbjct: 332 FITTGSTDHVIRIYYLGSEVPEKIAELESHTDKV--VAVQFCNNGDSLRFVSGSRDGTAR 389
Query: 1203 VW 1204
+W
Sbjct: 390 IW 391
Score = 56.8 bits (131), Expect = 5e-07
Identities = 56/218 (25%), Positives = 89/218 (40%), Gaps = 23/218 (10%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH S+ C+ R + + TGS+D V +W + + H A + +A +L+
Sbjct: 178 GHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLI 237
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV---IQDGNIFITGS-QDGTVCTWNV 807
+G D V + L A V L H S+TS++ + N ++T + DGT+C W
Sbjct: 238 AAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQW 297
Query: 808 ENFTL---------LSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGT----YL 854
T+ GV I + +F+ T G + +R + G+ +
Sbjct: 298 HVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITT--GSTDHVIRIYYLGSEVPEKI 355
Query: 855 HPLKRHKAKVKC--FCVAHDSSRVAVGCAD--QRIYLY 888
L+ H KV FC DS R G D RI+ Y
Sbjct: 356 AELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQY 393
Score = 43.6 bits (98), Expect = 0.005
Identities = 23/75 (30%), Positives = 36/75 (48%)
Query: 731 KILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDG 790
+IL H++ V CVA + + +G DD V I + DG L+ L H ++ + V +
Sbjct: 175 RILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYEN 234
Query: 791 NIFITGSQDGTVCTW 805
+ GS D V W
Sbjct: 235 TLIAAGSCDKVVRVW 249
Score = 43.6 bits (98), Expect = 0.005
Identities = 34/148 (22%), Positives = 62/148 (41%), Gaps = 16/148 (10%)
Query: 677 QLWHIMSNSKVHTFKGHSGSI----LCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK--- 729
++W + + + V +GHS SI C ++YL + D ++ W H +K
Sbjct: 247 RVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRD 306
Query: 730 --TKILEHIAP---VLCVAAIVNRSLVISGGDDSAVIITSLVDGA--LVTKLDHHRGSVT 782
K E P + C + + +G D + I L + +L+ H V
Sbjct: 307 RPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVV 366
Query: 783 SVKVIQDGNI--FITGSQDGTVCTWNVE 808
+V+ +G+ F++GS+DGT W +
Sbjct: 367 AVQFCNNGDSLRFVSGSRDGTARIWQYQ 394
Score = 41.5 bits (93), Expect = 0.021
Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 4/89 (4%)
Query: 952 STTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHI 1011
+T + LL + IS + V+ + L A+G +VRVW L T A L GH I
Sbjct: 208 ATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASI 267
Query: 1012 TCVTFSPN----NLLVLSGSEDRTVVVWQ 1036
T + F P+ N + S D T+ WQ
Sbjct: 268 TSIQFCPSTKGTNRYLTSTGADGTICFWQ 296
Score = 36.3 bits (80), Expect = 0.81
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + T +GHS I M V E+ + GS D V VW L T A + H
Sbjct: 205 KIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHS 264
Query: 737 APVLCVAAI-----VNRSLVISGGD 756
A + + NR L +G D
Sbjct: 265 ASITSIQFCPSTKGTNRYLTSTGAD 289
Score = 34.7 bits (76), Expect = 2.5
Identities = 17/80 (21%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Query: 1167 KLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVK 1226
K+ + ++GH V CVA + + ++ +GS DC + +W + +++ +
Sbjct: 171 KMHKRILGHLSSVYCVAFDRSGR-RIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMA 229
Query: 1227 VTGDGTIAVSCAEDKTLIIW 1246
V + T+ + + DK + +W
Sbjct: 230 VNYENTLIAAGSCDKVVRVW 249
>BC031227-1|AAH31227.2| 452|Homo sapiens WDR88 protein protein.
Length = 452
Score = 65.3 bits (152), Expect = 2e-09
Identities = 59/267 (22%), Positives = 109/267 (40%), Gaps = 12/267 (4%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSA-IQTLLMMSDG 1062
L+GH ++ F ++ +LSGS D TV +W D S ++ A + + D
Sbjct: 124 LSGHEHAVSTCHFCVDDTKLLSGSYDCTVKLWDPVDGSVVRDFEHRPKAPVVECSITGDS 183
Query: 1063 RRAMSSDRARNVHVWLVDSGIVLHSATGPS--ASIDVTLNMKYAVLSDGDNSVRIWSLAG 1120
R +++ + V W +++G +L + S + + KY V+S D I +
Sbjct: 184 SRVIAASYDKTVRAWDLETGKLLWKVRYDTFIVSCKFSPDGKY-VVSGFDVDHGICIMDA 242
Query: 1121 GDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDG-GKLSQVLVGHSDIV 1179
+ + + H IT DSQ V + S+D +K+W + L + HS+ +
Sbjct: 243 ENITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAI 302
Query: 1180 TCVAVSITNKTQVVSGSWDCNLIVWDINT------XXXXXXXXXXXXKVTCVKVTGDGTI 1233
+ + + + + SWD NL +W+++T V+ D +
Sbjct: 303 SNCCFTFSGHF-LCTSSWDKNLKIWNVHTGEFRNCGACVTLMQGHEGSVSSCHFARDSSF 361
Query: 1234 AVSCAEDKTLIIWETKRGLALTSFSLH 1260
+S D+T+ IW+ G S H
Sbjct: 362 LISGGFDRTVAIWDVAEGYRKLSLKGH 388
Score = 65.3 bits (152), Expect = 2e-09
Identities = 56/226 (24%), Positives = 100/226 (44%), Gaps = 11/226 (4%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE-DRTVVVWQLAD-NSPSLTYK 1047
VR W L T +L + ++C FSP+ V+SG + D + + + + S+
Sbjct: 195 VRAWDLETGKLLWKVRYDTFIVSC-KFSPDGKYVVSGFDVDHGICIMDAENITTVSVIKD 253
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSAT-GPSASID---VTLNMKY 1103
H+ +I + D +R S R + +W V S L + T S +I T + +
Sbjct: 254 HHTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGHF 313
Query: 1104 AVLSDGDNSVRIWSLAGGDNSEDNRRSV---SHAERITCFALTADSQHVVTGSMDMSLKV 1160
S D +++IW++ G+ H ++ DS +++G D ++ +
Sbjct: 314 LCTSSWDKNLKIWNVHTGEFRNCGACVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAI 373
Query: 1161 WKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
W + G L GH+D V VA+S NK ++S S D + +W+I
Sbjct: 374 WDVAEGYRKLSLKGHNDWVMDVAIS-NNKKWILSASKDRTMRLWNI 418
Score = 63.3 bits (147), Expect = 6e-09
Identities = 69/300 (23%), Positives = 122/300 (40%), Gaps = 23/300 (7%)
Query: 746 VNRSLVISGGDDSAVIITSLVDGALVTKLDHH-RGSVTSVKVIQDGNIFITGSQDGTVCT 804
V+ + ++SG D V + VDG++V +H + V + D + I S D TV
Sbjct: 138 VDDTKLLSGSYDCTVKLWDPVDGSVVRDFEHRPKAPVVECSITGDSSRVIAASYDKTVRA 197
Query: 805 WNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT-LQGDNELHLRTFITGTYLHPLKRHKAK 863
W++E LL V I + D ++++ D+ + + T + +K H +
Sbjct: 198 WDLETGKLLWKVRYDTFIVSCKFSPDGKYVVSGFDVDHGICIMDAENITTVSVIKDHHTR 257
Query: 864 -VKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXXXX--XXXXXXFLLAA 920
+ C DS RVA D+ I ++ + S L T FL +
Sbjct: 258 SITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFLCTS 317
Query: 921 GGNR-VTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQ 979
++ + I++ HT + FR +TL+Q + +S +RD
Sbjct: 318 SWDKNLKIWNVHTGE----FR----------NCGACVTLMQGHEGS---VSSCHFARDSS 360
Query: 980 LGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLAD 1039
SG V +W ++ + +L GH + V S N +LS S+DRT+ +W + +
Sbjct: 361 FLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAISNNKKWILSASKDRTMRLWNIEE 420
Score = 58.4 bits (135), Expect = 2e-07
Identities = 39/139 (28%), Positives = 63/139 (45%), Gaps = 7/139 (5%)
Query: 677 QLWHIMSNSKVHTF-KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL------AVK 729
++W + S + + T K HS +I C T +L T S D ++ +W++HT A
Sbjct: 281 KIWDVTSQATLLTITKAHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNCGACV 340
Query: 730 TKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQD 789
T + H V + S +ISGG D V I + +G L H V V + +
Sbjct: 341 TLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAISNN 400
Query: 790 GNIFITGSQDGTVCTWNVE 808
++ S+D T+ WN+E
Sbjct: 401 KKWILSASKDRTMRLWNIE 419
Score = 52.0 bits (119), Expect = 2e-05
Identities = 56/225 (24%), Positives = 94/225 (41%), Gaps = 12/225 (5%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMC-VTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEH 735
+LW + S V F+ + + C +T +S ++ S D +V WDL T + K+
Sbjct: 153 KLWDPVDGSVVRDFEHRPKAPVVECSITGDSSRVIAASYDKTVRAWDLETGKLLWKVRYD 212
Query: 736 IAPVLCVAAIVNRSLVISGGD-DSAVIITSLVDGALVTKL-DHHRGSVTSVKVIQDGNIF 793
V C + + V+SG D D + I + V+ + DHH S+TS D
Sbjct: 213 TFIVSCKFS-PDGKYVVSGFDVDHGICIMDAENITTVSVIKDHHTRSITSCCFDPDSQRV 271
Query: 794 ITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFD--VTDDNVFLLTLQGDNELHLRTFITG 851
+ S D + W+V + L T+T I + T FL T D L + TG
Sbjct: 272 ASVSLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTG 331
Query: 852 TY------LHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ + ++ H+ V A DSS + G D+ + ++ +
Sbjct: 332 EFRNCGACVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDV 376
Score = 52.0 bits (119), Expect = 2e-05
Identities = 30/137 (21%), Positives = 66/137 (48%), Gaps = 9/137 (6%)
Query: 950 TKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ------AT 1003
T T +T+ +A S+ I C S G + +++W + T +
Sbjct: 286 TSQATLLTITKAH-SNAISNCCFTFS--GHFLCTSSWDKNLKIWNVHTGEFRNCGACVTL 342
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR 1063
+ GH G ++ F+ ++ ++SG DRTV +W +A+ L+ KGH+ + + + ++ +
Sbjct: 343 MQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAISNNKK 402
Query: 1064 RAMSSDRARNVHVWLVD 1080
+S+ + R + +W ++
Sbjct: 403 WILSASKDRTMRLWNIE 419
Score = 46.4 bits (105), Expect = 8e-04
Identities = 40/161 (24%), Positives = 68/161 (42%), Gaps = 8/161 (4%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVL--CVAAIVNRSL 750
H+ SI C +SQ + + S D + +WD+ + A I + + + C L
Sbjct: 255 HTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFL 314
Query: 751 VISGGDDSAVIITSLVD-----GALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
S D + I GA VT + H GSV+S +D + I+G D TV W
Sbjct: 315 CTSSWDKNLKIWNVHTGEFRNCGACVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIW 374
Query: 806 NV-ENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHL 845
+V E + LS + ++++ ++L+ D + L
Sbjct: 375 DVAEGYRKLSLKGHNDWVMDVAISNNKKWILSASKDRTMRL 415
Score = 45.2 bits (102), Expect = 0.002
Identities = 51/209 (24%), Positives = 87/209 (41%), Gaps = 12/209 (5%)
Query: 693 HSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEH--IAPVLCVAAIVNRSL 750
H+ S CV + LL+GS D +V +WD +V + EH APV+ + + S
Sbjct: 129 HAVSTCHFCV--DDTKLLSGSYDCTVKLWDPVDGSV-VRDFEHRPKAPVVECSITGDSSR 185
Query: 751 VISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITG-SQDGTVCTWNVEN 809
VI+ D V L G L+ K+ + + S K DG ++G D +C + EN
Sbjct: 186 VIAASYDKTVRAWDLETGKLLWKV-RYDTFIVSCKFSPDGKYVVSGFDVDHGICIMDAEN 244
Query: 810 FTLLSTV----TAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVK 865
T +S + T + FD V ++L ++ T T L K H +
Sbjct: 245 ITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDVT-SQATLLTITKAHSNAIS 303
Query: 866 CFCVAHDSSRVAVGCADQRIYLYSLHSAQ 894
C + D+ + ++++H+ +
Sbjct: 304 NCCFTFSGHFLCTSSWDKNLKIWNVHTGE 332
>BC014988-1|AAH14988.1| 919|Homo sapiens PWP2 periodic tryptophan
protein homolog (yeast) protein.
Length = 919
Score = 65.3 bits (152), Expect = 2e-09
Identities = 64/317 (20%), Positives = 123/317 (38%), Gaps = 8/317 (2%)
Query: 941 PTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRL 1000
P ++ K + K + ++ D ++ + L +G A G+ + +L L
Sbjct: 263 PAEEEKTGKVKYSRLAKYFFNKEGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNL 322
Query: 1001 QATLNGHIGHITCVTFSPNNLLVLSGSEDR-TVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
+L+ I V + + + G ++VW+ S L +GH +++ L
Sbjct: 323 IHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYS 382
Query: 1060 SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMK-YAVLSDG-DNSVRIW 1116
DG+ ++ V VW SG + T S+ + VT Y V++ D +VR +
Sbjct: 383 PDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 1117 SLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD-MSLKVWKLDGGKLSQVLVGH 1175
L N + + +C A+ A + V G+ D + VW + G+L VL GH
Sbjct: 443 DLHRYRNFRTF--TSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGH 500
Query: 1176 SDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAV 1235
++ + + K+ + S SWD + +WD+ V + DG
Sbjct: 501 EGPISGLCFN-PMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTIRPDGAELA 559
Query: 1236 SCAEDKTLIIWETKRGL 1252
+ + W+ + +
Sbjct: 560 VATLNSQITFWDPENAV 576
Score = 61.3 bits (142), Expect = 2e-08
Identities = 47/228 (20%), Positives = 90/228 (39%), Gaps = 4/228 (1%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS-VIVWDLHT 725
LV ++G L + + +H+ SI + + ++ G ++VW+ +
Sbjct: 303 LVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQS 362
Query: 726 LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVK 785
+ K H ++ +A + +++GGDD V + + + G H VT V
Sbjct: 363 ESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVT 422
Query: 786 VIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDD---NVFLLTLQGDNE 842
G + +T S DGTV +++ + T T+ P V D + Q E
Sbjct: 423 FTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFE 482
Query: 843 LHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ + + TG L L H+ + C S +A D+ + L+ +
Sbjct: 483 IFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 60.1 bits (139), Expect = 6e-08
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 2/152 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L +P GQ++V G ++W+ +S TF HS + + T ++T S D +
Sbjct: 379 LAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGT 438
Query: 718 VIVWDLHTLA-VKTKILEHIAPVLCVAAIVNRSLVISGGDDS-AVIITSLVDGALVTKLD 775
V +DLH +T CVA + +V +G DS + + S+ G L+ L
Sbjct: 439 VRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLS 498
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
H G ++ + ++ + S D TV W++
Sbjct: 499 GHEGPISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 50.0 bits (114), Expect = 6e-05
Identities = 30/122 (24%), Positives = 56/122 (45%), Gaps = 1/122 (0%)
Query: 970 SCLEVSRDGQLGASGCARGL-VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
SC+ V G++ ++G + VW + T RL L+GH G I+ + F+P ++ S S
Sbjct: 462 SCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASW 521
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D+TV +W + D+ + +S + + DG + + W ++ + S
Sbjct: 522 DKTVRLWDMFDSWRTKETLALTSDALAVTIRPDGAELAVATLNSQITFWDPENAVQTGSI 581
Query: 1089 TG 1090
G
Sbjct: 582 EG 583
Score = 49.2 bits (112), Expect = 1e-04
Identities = 46/224 (20%), Positives = 90/224 (40%), Gaps = 8/224 (3%)
Query: 962 EQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNL 1021
+Q + L S DGQ +G G V+VW + T H +T VTF+
Sbjct: 369 QQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGY 428
Query: 1022 LVLSGSEDRTVVVWQLADNSPSLTYKG-HSSAIQTLLMMSDGR-RAMSSDRARNVHVWLV 1079
+V++ S D TV + L T+ + + + + G + + + + VW +
Sbjct: 429 VVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSM 488
Query: 1080 DSGIVLHSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAER 1136
+G +L +G I + N +VL+ D +VR+W + +++ S A
Sbjct: 489 QTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALA 548
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVT 1180
+T + D + +++ + W + + + G D+ T
Sbjct: 549 VT---IRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKT 589
Score = 42.7 bits (96), Expect = 0.009
Identities = 41/170 (24%), Positives = 71/170 (41%), Gaps = 12/170 (7%)
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
+Y V D V++W+ G H+ +T TA VVT SMD +++ +
Sbjct: 386 QYIVTGGDDGKVKVWNTLSGFCFVT---FTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 1162 KLDGGKLSQVLVGHSDI-VTCVAVSITNKTQVVSGSWDC-NLIVWDINTXXXXXXXXXXX 1219
L + + +CVAV + + V +G+ D + VW + T
Sbjct: 443 DLHRYRNFRTFTSPRPTQFSCVAVDASGEI-VSAGAQDSFEIFVWSMQTGRLLDVLSGHE 501
Query: 1220 XKVTCVKVTGDGTIAVSCAEDKTLIIWE------TKRGLALTSFSLHVPL 1263
++ + ++ S + DKT+ +W+ TK LALTS +L V +
Sbjct: 502 GPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTI 551
Score = 33.9 bits (74), Expect = 4.3
Identities = 54/205 (26%), Positives = 87/205 (42%), Gaps = 15/205 (7%)
Query: 1014 VTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARN 1073
+ F+ N V+S +R V V+ L +N ++ + + DGR A+ D +
Sbjct: 20 LNFTCNGNSVISPVGNR-VTVFDLKNNKSDTLPLATRYNVKCVGLSPDGRLAIIVDEGGD 78
Query: 1074 -VHVWLVDSGIVLH-SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSV 1131
+ V LV ++ H G S+ + + + V++ G N +++ A G E N +
Sbjct: 79 ALLVSLVCRSVLHHFHFKGSVHSVSFSPDGRKFVVTKG-NIAQMYH-APGKKREFNAFVL 136
Query: 1132 SHA-----ERITCFALTADSQHVVTGSMDMSLKVWKLD--GGKLSQVLVGHSD-IVTCVA 1183
+ TC T DS+ V GS DMS V+ + + L GH D IV C
Sbjct: 137 DKTYFGPYDETTCIDWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKDAIVACFF 196
Query: 1184 VSITNKTQVVSGSWDCNLIVWDINT 1208
S N + S S D L +W +T
Sbjct: 197 ES--NSLDLYSLSQDGVLCMWQCDT 219
>BC013309-1|AAH13309.1| 919|Homo sapiens PWP2 periodic tryptophan
protein homolog (yeast) protein.
Length = 919
Score = 65.3 bits (152), Expect = 2e-09
Identities = 64/317 (20%), Positives = 123/317 (38%), Gaps = 8/317 (2%)
Query: 941 PTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRL 1000
P ++ K + K + ++ D ++ + L +G A G+ + +L L
Sbjct: 263 PAEEEKTGKVKYSRLAKYFFNKEGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNL 322
Query: 1001 QATLNGHIGHITCVTFSPNNLLVLSGSEDR-TVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
+L+ I V + + + G ++VW+ S L +GH +++ L
Sbjct: 323 IHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYS 382
Query: 1060 SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMK-YAVLSDG-DNSVRIW 1116
DG+ ++ V VW SG + T S+ + VT Y V++ D +VR +
Sbjct: 383 PDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 1117 SLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD-MSLKVWKLDGGKLSQVLVGH 1175
L N + + +C A+ A + V G+ D + VW + G+L VL GH
Sbjct: 443 DLHRYRNFRTF--TSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGH 500
Query: 1176 SDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAV 1235
++ + + K+ + S SWD + +WD+ V + DG
Sbjct: 501 EGPISGLCFN-PMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTIRPDGAELA 559
Query: 1236 SCAEDKTLIIWETKRGL 1252
+ + W+ + +
Sbjct: 560 VATLNSQITFWDPENAV 576
Score = 61.3 bits (142), Expect = 2e-08
Identities = 47/228 (20%), Positives = 90/228 (39%), Gaps = 4/228 (1%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS-VIVWDLHT 725
LV ++G L + + +H+ SI + + ++ G ++VW+ +
Sbjct: 303 LVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQS 362
Query: 726 LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVK 785
+ K H ++ +A + +++GGDD V + + + G H VT V
Sbjct: 363 ESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVT 422
Query: 786 VIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDD---NVFLLTLQGDNE 842
G + +T S DGTV +++ + T T+ P V D + Q E
Sbjct: 423 FTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFE 482
Query: 843 LHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ + + TG L L H+ + C S +A D+ + L+ +
Sbjct: 483 IFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 60.1 bits (139), Expect = 6e-08
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 2/152 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L +P GQ++V G ++W+ +S TF HS + + T ++T S D +
Sbjct: 379 LAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGT 438
Query: 718 VIVWDLHTLA-VKTKILEHIAPVLCVAAIVNRSLVISGGDDS-AVIITSLVDGALVTKLD 775
V +DLH +T CVA + +V +G DS + + S+ G L+ L
Sbjct: 439 VRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLS 498
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
H G ++ + ++ + S D TV W++
Sbjct: 499 GHEGPISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 50.0 bits (114), Expect = 6e-05
Identities = 30/122 (24%), Positives = 56/122 (45%), Gaps = 1/122 (0%)
Query: 970 SCLEVSRDGQLGASGCARGL-VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
SC+ V G++ ++G + VW + T RL L+GH G I+ + F+P ++ S S
Sbjct: 462 SCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASW 521
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D+TV +W + D+ + +S + + DG + + W ++ + S
Sbjct: 522 DKTVRLWDMFDSWRTKETLALTSDALAVTIRPDGAELAVATLNSQITFWDPENAVQTGSI 581
Query: 1089 TG 1090
G
Sbjct: 582 EG 583
Score = 49.2 bits (112), Expect = 1e-04
Identities = 46/224 (20%), Positives = 90/224 (40%), Gaps = 8/224 (3%)
Query: 962 EQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNL 1021
+Q + L S DGQ +G G V+VW + T H +T VTF+
Sbjct: 369 QQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGY 428
Query: 1022 LVLSGSEDRTVVVWQLADNSPSLTYKG-HSSAIQTLLMMSDGR-RAMSSDRARNVHVWLV 1079
+V++ S D TV + L T+ + + + + G + + + + VW +
Sbjct: 429 VVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSM 488
Query: 1080 DSGIVLHSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAER 1136
+G +L +G I + N +VL+ D +VR+W + +++ S A
Sbjct: 489 QTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALA 548
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVT 1180
+T + D + +++ + W + + + G D+ T
Sbjct: 549 VT---IRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKT 589
Score = 42.7 bits (96), Expect = 0.009
Identities = 41/170 (24%), Positives = 71/170 (41%), Gaps = 12/170 (7%)
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
+Y V D V++W+ G H+ +T TA VVT SMD +++ +
Sbjct: 386 QYIVTGGDDGKVKVWNTLSGFCFVT---FTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 1162 KLDGGKLSQVLVGHSDI-VTCVAVSITNKTQVVSGSWDC-NLIVWDINTXXXXXXXXXXX 1219
L + + +CVAV + + V +G+ D + VW + T
Sbjct: 443 DLHRYRNFRTFTSPRPTQFSCVAVDASGEI-VSAGAQDSFEIFVWSMQTGRLLDVLSGHE 501
Query: 1220 XKVTCVKVTGDGTIAVSCAEDKTLIIWE------TKRGLALTSFSLHVPL 1263
++ + ++ S + DKT+ +W+ TK LALTS +L V +
Sbjct: 502 GPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTI 551
Score = 33.9 bits (74), Expect = 4.3
Identities = 54/205 (26%), Positives = 87/205 (42%), Gaps = 15/205 (7%)
Query: 1014 VTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARN 1073
+ F+ N V+S +R V V+ L +N ++ + + DGR A+ D +
Sbjct: 20 LNFTCNGNSVISPVGNR-VTVFDLKNNKSDTLPLATRYNVKCVGLSPDGRLAIIVDEGGD 78
Query: 1074 -VHVWLVDSGIVLH-SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSV 1131
+ V LV ++ H G S+ + + + V++ G N +++ A G E N +
Sbjct: 79 ALLVSLVCRSVLHHFHFKGSVHSVSFSPDGRKFVVTKG-NIAQMYH-APGKKREFNAFVL 136
Query: 1132 SHA-----ERITCFALTADSQHVVTGSMDMSLKVWKLD--GGKLSQVLVGHSD-IVTCVA 1183
+ TC T DS+ V GS DMS V+ + + L GH D IV C
Sbjct: 137 DKTYFGPYDETTCIDWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKDAIVACFF 196
Query: 1184 VSITNKTQVVSGSWDCNLIVWDINT 1208
S N + S S D L +W +T
Sbjct: 197 ES--NSLDLYSLSQDGVLCMWQCDT 219
>AY497047-1|AAS45472.1| 1631|Homo sapiens bromodomain and WD repeat
domain containing 3 variant BRWD3-B protein.
Length = 1631
Score = 65.3 bits (152), Expect = 2e-09
Identities = 76/341 (22%), Positives = 137/341 (40%), Gaps = 35/341 (10%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLS 1025
L + C+ R G+ +G LV++W RL ATL GH I+ + + N L+ +
Sbjct: 9 LSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAA 68
Query: 1026 GSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR---RAMSSDRARNV------HV 1076
GS D+ V VW L +P +GHS++I ++ + R ++S A HV
Sbjct: 69 GSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHV 128
Query: 1077 WLV---DSGIVLHSATGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
+ D + + P I + + D+ +RI+ L G + E
Sbjct: 129 KTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYL-GSEVPEKIAEL 187
Query: 1131 VSHAERITC--FALTADSQHVVTGSMDMSLKVWKLDGGKLSQV-------LVGHS----- 1176
SH +++ F DS V+GS D + ++W+ + + + G++
Sbjct: 188 ESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMTGNNLPSGE 247
Query: 1177 DIVTCVAVSIT----NKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV-TGDG 1231
D +T + V++ T V++ + L VW+ T +V ++ D
Sbjct: 248 DKITKLKVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQ 307
Query: 1232 TIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLGFQITSDC 1272
I +S D + IW+ RG + ++ + G DC
Sbjct: 308 RIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDC 348
Score = 59.7 bits (138), Expect = 8e-08
Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 5/125 (4%)
Query: 1127 NRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSI 1186
++R + H + C A + + TGS D +K+W D G+L L GHS ++ +AV+
Sbjct: 2 HKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNY 61
Query: 1187 TNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVT----CVKVTGDGTIAVSCAEDKT 1242
N T + +GS D + VW + T +T C G S D T
Sbjct: 62 EN-TLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGT 120
Query: 1243 LIIWE 1247
+ W+
Sbjct: 121 ICFWQ 125
Score = 56.8 bits (131), Expect = 5e-07
Identities = 56/218 (25%), Positives = 89/218 (40%), Gaps = 23/218 (10%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH S+ C+ R + + TGS+D V +W + + H A + +A +L+
Sbjct: 7 GHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLI 66
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV---IQDGNIFITGS-QDGTVCTWNV 807
+G D V + L A V L H S+TS++ + N ++T + DGT+C W
Sbjct: 67 AAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQW 126
Query: 808 ENFTL---------LSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGT----YL 854
T+ GV I + +F+ T G + +R + G+ +
Sbjct: 127 HVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITT--GSTDHVIRIYYLGSEVPEKI 184
Query: 855 HPLKRHKAKVKC--FCVAHDSSRVAVGCAD--QRIYLY 888
L+ H KV FC DS R G D RI+ Y
Sbjct: 185 AELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQY 222
Score = 56.0 bits (129), Expect = 9e-07
Identities = 52/217 (23%), Positives = 88/217 (40%), Gaps = 21/217 (9%)
Query: 1006 GHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRA 1065
GH+ + CV F + + +GS+D V +W D T +GHS+ I + + +
Sbjct: 7 GHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLI 66
Query: 1066 MSSDRARNVHVWLVDSGIVLHSATGPSASI-------DVTLNMKYAVLSDGDNSVRIWSL 1118
+ + V VW + + + G SASI +Y + D ++ W
Sbjct: 67 AAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQW 126
Query: 1119 AGGDNSEDNRRSVSHAER------ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQV- 1171
+ R V ER I+C + ++ + TGS D ++++ L ++
Sbjct: 127 -HVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIA 185
Query: 1172 -LVGHSDIVTCVAVSITN---KTQVVSGSWDCNLIVW 1204
L H+D V VAV N + VSGS D +W
Sbjct: 186 ELESHTDKV--VAVQFCNNGDSLRFVSGSRDGTARIW 220
Score = 43.6 bits (98), Expect = 0.005
Identities = 23/75 (30%), Positives = 36/75 (48%)
Query: 731 KILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDG 790
+IL H++ V CVA + + +G DD V I + DG L+ L H ++ + V +
Sbjct: 4 RILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYEN 63
Query: 791 NIFITGSQDGTVCTW 805
+ GS D V W
Sbjct: 64 TLIAAGSCDKVVRVW 78
Score = 43.6 bits (98), Expect = 0.005
Identities = 34/148 (22%), Positives = 62/148 (41%), Gaps = 16/148 (10%)
Query: 677 QLWHIMSNSKVHTFKGHSGSI----LCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK--- 729
++W + + + V +GHS SI C ++YL + D ++ W H +K
Sbjct: 76 RVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRD 135
Query: 730 --TKILEHIAP---VLCVAAIVNRSLVISGGDDSAVIITSLVDGA--LVTKLDHHRGSVT 782
K E P + C + + +G D + I L + +L+ H V
Sbjct: 136 RPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVV 195
Query: 783 SVKVIQDGNI--FITGSQDGTVCTWNVE 808
+V+ +G+ F++GS+DGT W +
Sbjct: 196 AVQFCNNGDSLRFVSGSRDGTARIWQYQ 223
Score = 41.5 bits (93), Expect = 0.021
Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 4/89 (4%)
Query: 952 STTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHI 1011
+T + LL + IS + V+ + L A+G +VRVW L T A L GH I
Sbjct: 37 ATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASI 96
Query: 1012 TCVTFSPN----NLLVLSGSEDRTVVVWQ 1036
T + F P+ N + S D T+ WQ
Sbjct: 97 TSIQFCPSTKGTNRYLTSTGADGTICFWQ 125
Score = 36.3 bits (80), Expect = 0.81
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + T +GHS I M V E+ + GS D V VW L T A + H
Sbjct: 34 KIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHS 93
Query: 737 APVLCVAAI-----VNRSLVISGGD 756
A + + NR L +G D
Sbjct: 94 ASITSIQFCPSTKGTNRYLTSTGAD 118
>AY497046-1|AAS45471.1| 1802|Homo sapiens bromodomain and WD repeat
domain containing 3 variant BRWD3-A protein.
Length = 1802
Score = 65.3 bits (152), Expect = 2e-09
Identities = 76/341 (22%), Positives = 137/341 (40%), Gaps = 35/341 (10%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLS 1025
L + C+ R G+ +G LV++W RL ATL GH I+ + + N L+ +
Sbjct: 180 LSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAA 239
Query: 1026 GSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR---RAMSSDRARNV------HV 1076
GS D+ V VW L +P +GHS++I ++ + R ++S A HV
Sbjct: 240 GSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHV 299
Query: 1077 WLV---DSGIVLHSATGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
+ D + + P I + + D+ +RI+ L G + E
Sbjct: 300 KTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYL-GSEVPEKIAEL 358
Query: 1131 VSHAERITC--FALTADSQHVVTGSMDMSLKVWKLDGGKLSQV-------LVGHS----- 1176
SH +++ F DS V+GS D + ++W+ + + + G++
Sbjct: 359 ESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMTGNNLPSGE 418
Query: 1177 DIVTCVAVSIT----NKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV-TGDG 1231
D +T + V++ T V++ + L VW+ T +V ++ D
Sbjct: 419 DKITKLKVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQ 478
Query: 1232 TIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLGFQITSDC 1272
I +S D + IW+ RG + ++ + G DC
Sbjct: 479 RIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDC 519
Score = 57.2 bits (132), Expect = 4e-07
Identities = 57/242 (23%), Positives = 99/242 (40%), Gaps = 23/242 (9%)
Query: 983 SGCAR-GLVRVWQLSTH-RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN 1040
+GC+R G + H ++ + GH+ + CV F + + +GS+D V +W D
Sbjct: 153 TGCSRFGHIFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDG 212
Query: 1041 SPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI----- 1095
T +GHS+ I + + + + + V VW + + + G SASI
Sbjct: 213 RLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQF 272
Query: 1096 --DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAER------ITCFALTADSQ 1147
+Y + D ++ W + R V ER I+C + ++
Sbjct: 273 CPSTKGTNRYLTSTGADGTICFWQW-HVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGM 331
Query: 1148 HVVTGSMDMSLKVWKLDGGKLSQV--LVGHSDIVTCVAVSITN---KTQVVSGSWDCNLI 1202
+ TGS D ++++ L ++ L H+D V VAV N + VSGS D
Sbjct: 332 FITTGSTDHVIRIYYLGSEVPEKIAELESHTDKV--VAVQFCNNGDSLRFVSGSRDGTAR 389
Query: 1203 VW 1204
+W
Sbjct: 390 IW 391
Score = 56.8 bits (131), Expect = 5e-07
Identities = 56/218 (25%), Positives = 89/218 (40%), Gaps = 23/218 (10%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH S+ C+ R + + TGS+D V +W + + H A + +A +L+
Sbjct: 178 GHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLI 237
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV---IQDGNIFITGS-QDGTVCTWNV 807
+G D V + L A V L H S+TS++ + N ++T + DGT+C W
Sbjct: 238 AAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQW 297
Query: 808 ENFTL---------LSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGT----YL 854
T+ GV I + +F+ T G + +R + G+ +
Sbjct: 298 HVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITT--GSTDHVIRIYYLGSEVPEKI 355
Query: 855 HPLKRHKAKVKC--FCVAHDSSRVAVGCAD--QRIYLY 888
L+ H KV FC DS R G D RI+ Y
Sbjct: 356 AELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQY 393
Score = 43.6 bits (98), Expect = 0.005
Identities = 23/75 (30%), Positives = 36/75 (48%)
Query: 731 KILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDG 790
+IL H++ V CVA + + +G DD V I + DG L+ L H ++ + V +
Sbjct: 175 RILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYEN 234
Query: 791 NIFITGSQDGTVCTW 805
+ GS D V W
Sbjct: 235 TLIAAGSCDKVVRVW 249
Score = 43.6 bits (98), Expect = 0.005
Identities = 34/148 (22%), Positives = 62/148 (41%), Gaps = 16/148 (10%)
Query: 677 QLWHIMSNSKVHTFKGHSGSI----LCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK--- 729
++W + + + V +GHS SI C ++YL + D ++ W H +K
Sbjct: 247 RVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRD 306
Query: 730 --TKILEHIAP---VLCVAAIVNRSLVISGGDDSAVIITSLVDGA--LVTKLDHHRGSVT 782
K E P + C + + +G D + I L + +L+ H V
Sbjct: 307 RPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVV 366
Query: 783 SVKVIQDGNI--FITGSQDGTVCTWNVE 808
+V+ +G+ F++GS+DGT W +
Sbjct: 367 AVQFCNNGDSLRFVSGSRDGTARIWQYQ 394
Score = 41.5 bits (93), Expect = 0.021
Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 4/89 (4%)
Query: 952 STTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHI 1011
+T + LL + IS + V+ + L A+G +VRVW L T A L GH I
Sbjct: 208 ATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASI 267
Query: 1012 TCVTFSPN----NLLVLSGSEDRTVVVWQ 1036
T + F P+ N + S D T+ WQ
Sbjct: 268 TSIQFCPSTKGTNRYLTSTGADGTICFWQ 296
Score = 36.3 bits (80), Expect = 0.81
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + T +GHS I M V E+ + GS D V VW L T A + H
Sbjct: 205 KIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHS 264
Query: 737 APVLCVAAI-----VNRSLVISGGD 756
A + + NR L +G D
Sbjct: 265 ASITSIQFCPSTKGTNRYLTSTGAD 289
Score = 34.7 bits (76), Expect = 2.5
Identities = 17/80 (21%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Query: 1167 KLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVK 1226
K+ + ++GH V CVA + + ++ +GS DC + +W + +++ +
Sbjct: 171 KMHKRILGHLSSVYCVAFDRSGR-RIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMA 229
Query: 1227 VTGDGTIAVSCAEDKTLIIW 1246
V + T+ + + DK + +W
Sbjct: 230 VNYENTLIAAGSCDKVVRVW 249
>AL669934-1|CAI95405.1| 1802|Homo sapiens bromodomain and WD repeat
domain containing 3 protein.
Length = 1802
Score = 65.3 bits (152), Expect = 2e-09
Identities = 76/341 (22%), Positives = 137/341 (40%), Gaps = 35/341 (10%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLS 1025
L + C+ R G+ +G LV++W RL ATL GH I+ + + N L+ +
Sbjct: 180 LSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAA 239
Query: 1026 GSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR---RAMSSDRARNV------HV 1076
GS D+ V VW L +P +GHS++I ++ + R ++S A HV
Sbjct: 240 GSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHV 299
Query: 1077 WLV---DSGIVLHSATGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
+ D + + P I + + D+ +RI+ L G + E
Sbjct: 300 KTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYL-GSEVPEKIAEL 358
Query: 1131 VSHAERITC--FALTADSQHVVTGSMDMSLKVWKLDGGKLSQV-------LVGHS----- 1176
SH +++ F DS V+GS D + ++W+ + + + G++
Sbjct: 359 ESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMTGNNLPSGE 418
Query: 1177 DIVTCVAVSIT----NKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV-TGDG 1231
D +T + V++ T V++ + L VW+ T +V ++ D
Sbjct: 419 DKITKLKVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQ 478
Query: 1232 TIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLGFQITSDC 1272
I +S D + IW+ RG + ++ + G DC
Sbjct: 479 RIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDC 519
Score = 57.2 bits (132), Expect = 4e-07
Identities = 57/242 (23%), Positives = 99/242 (40%), Gaps = 23/242 (9%)
Query: 983 SGCAR-GLVRVWQLSTH-RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN 1040
+GC+R G + H ++ + GH+ + CV F + + +GS+D V +W D
Sbjct: 153 TGCSRFGHIFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDG 212
Query: 1041 SPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI----- 1095
T +GHS+ I + + + + + V VW + + + G SASI
Sbjct: 213 RLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQF 272
Query: 1096 --DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAER------ITCFALTADSQ 1147
+Y + D ++ W + R V ER I+C + ++
Sbjct: 273 CPSTKGTNRYLTSTGADGTICFWQW-HVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGM 331
Query: 1148 HVVTGSMDMSLKVWKLDGGKLSQV--LVGHSDIVTCVAVSITN---KTQVVSGSWDCNLI 1202
+ TGS D ++++ L ++ L H+D V VAV N + VSGS D
Sbjct: 332 FITTGSTDHVIRIYYLGSEVPEKIAELESHTDKV--VAVQFCNNGDSLRFVSGSRDGTAR 389
Query: 1203 VW 1204
+W
Sbjct: 390 IW 391
Score = 56.8 bits (131), Expect = 5e-07
Identities = 56/218 (25%), Positives = 89/218 (40%), Gaps = 23/218 (10%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH S+ C+ R + + TGS+D V +W + + H A + +A +L+
Sbjct: 178 GHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLI 237
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV---IQDGNIFITGS-QDGTVCTWNV 807
+G D V + L A V L H S+TS++ + N ++T + DGT+C W
Sbjct: 238 AAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQW 297
Query: 808 ENFTL---------LSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGT----YL 854
T+ GV I + +F+ T G + +R + G+ +
Sbjct: 298 HVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITT--GSTDHVIRIYYLGSEVPEKI 355
Query: 855 HPLKRHKAKVKC--FCVAHDSSRVAVGCAD--QRIYLY 888
L+ H KV FC DS R G D RI+ Y
Sbjct: 356 AELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQY 393
Score = 43.6 bits (98), Expect = 0.005
Identities = 23/75 (30%), Positives = 36/75 (48%)
Query: 731 KILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDG 790
+IL H++ V CVA + + +G DD V I + DG L+ L H ++ + V +
Sbjct: 175 RILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYEN 234
Query: 791 NIFITGSQDGTVCTW 805
+ GS D V W
Sbjct: 235 TLIAAGSCDKVVRVW 249
Score = 43.6 bits (98), Expect = 0.005
Identities = 34/148 (22%), Positives = 62/148 (41%), Gaps = 16/148 (10%)
Query: 677 QLWHIMSNSKVHTFKGHSGSI----LCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK--- 729
++W + + + V +GHS SI C ++YL + D ++ W H +K
Sbjct: 247 RVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRD 306
Query: 730 --TKILEHIAP---VLCVAAIVNRSLVISGGDDSAVIITSLVDGA--LVTKLDHHRGSVT 782
K E P + C + + +G D + I L + +L+ H V
Sbjct: 307 RPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVV 366
Query: 783 SVKVIQDGNI--FITGSQDGTVCTWNVE 808
+V+ +G+ F++GS+DGT W +
Sbjct: 367 AVQFCNNGDSLRFVSGSRDGTARIWQYQ 394
Score = 41.5 bits (93), Expect = 0.021
Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 4/89 (4%)
Query: 952 STTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHI 1011
+T + LL + IS + V+ + L A+G +VRVW L T A L GH I
Sbjct: 208 ATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASI 267
Query: 1012 TCVTFSPN----NLLVLSGSEDRTVVVWQ 1036
T + F P+ N + S D T+ WQ
Sbjct: 268 TSIQFCPSTKGTNRYLTSTGADGTICFWQ 296
Score = 36.3 bits (80), Expect = 0.81
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + T +GHS I M V E+ + GS D V VW L T A + H
Sbjct: 205 KIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHS 264
Query: 737 APVLCVAAI-----VNRSLVISGGD 756
A + + NR L +G D
Sbjct: 265 ASITSIQFCPSTKGTNRYLTSTGAD 289
Score = 34.7 bits (76), Expect = 2.5
Identities = 17/80 (21%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Query: 1167 KLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVK 1226
K+ + ++GH V CVA + + ++ +GS DC + +W + +++ +
Sbjct: 171 KMHKRILGHLSSVYCVAFDRSGR-RIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMA 229
Query: 1227 VTGDGTIAVSCAEDKTLIIW 1246
V + T+ + + DK + +W
Sbjct: 230 VNYENTLIAAGSCDKVVRVW 249
>AL590031-1|CAI39936.2| 1802|Homo sapiens bromodomain and WD repeat
domain containing 3 protein.
Length = 1802
Score = 65.3 bits (152), Expect = 2e-09
Identities = 76/341 (22%), Positives = 137/341 (40%), Gaps = 35/341 (10%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLS 1025
L + C+ R G+ +G LV++W RL ATL GH I+ + + N L+ +
Sbjct: 180 LSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAA 239
Query: 1026 GSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR---RAMSSDRARNV------HV 1076
GS D+ V VW L +P +GHS++I ++ + R ++S A HV
Sbjct: 240 GSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHV 299
Query: 1077 WLV---DSGIVLHSATGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
+ D + + P I + + D+ +RI+ L G + E
Sbjct: 300 KTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYL-GSEVPEKIAEL 358
Query: 1131 VSHAERITC--FALTADSQHVVTGSMDMSLKVWKLDGGKLSQV-------LVGHS----- 1176
SH +++ F DS V+GS D + ++W+ + + + G++
Sbjct: 359 ESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMTGNNLPSGE 418
Query: 1177 DIVTCVAVSIT----NKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV-TGDG 1231
D +T + V++ T V++ + L VW+ T +V ++ D
Sbjct: 419 DKITKLKVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQ 478
Query: 1232 TIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLGFQITSDC 1272
I +S D + IW+ RG + ++ + G DC
Sbjct: 479 RIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDC 519
Score = 57.2 bits (132), Expect = 4e-07
Identities = 57/242 (23%), Positives = 99/242 (40%), Gaps = 23/242 (9%)
Query: 983 SGCAR-GLVRVWQLSTH-RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN 1040
+GC+R G + H ++ + GH+ + CV F + + +GS+D V +W D
Sbjct: 153 TGCSRFGHIFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDG 212
Query: 1041 SPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI----- 1095
T +GHS+ I + + + + + V VW + + + G SASI
Sbjct: 213 RLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQF 272
Query: 1096 --DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAER------ITCFALTADSQ 1147
+Y + D ++ W + R V ER I+C + ++
Sbjct: 273 CPSTKGTNRYLTSTGADGTICFWQW-HVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGM 331
Query: 1148 HVVTGSMDMSLKVWKLDGGKLSQV--LVGHSDIVTCVAVSITN---KTQVVSGSWDCNLI 1202
+ TGS D ++++ L ++ L H+D V VAV N + VSGS D
Sbjct: 332 FITTGSTDHVIRIYYLGSEVPEKIAELESHTDKV--VAVQFCNNGDSLRFVSGSRDGTAR 389
Query: 1203 VW 1204
+W
Sbjct: 390 IW 391
Score = 56.8 bits (131), Expect = 5e-07
Identities = 56/218 (25%), Positives = 89/218 (40%), Gaps = 23/218 (10%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH S+ C+ R + + TGS+D V +W + + H A + +A +L+
Sbjct: 178 GHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLI 237
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV---IQDGNIFITGS-QDGTVCTWNV 807
+G D V + L A V L H S+TS++ + N ++T + DGT+C W
Sbjct: 238 AAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQW 297
Query: 808 ENFTL---------LSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGT----YL 854
T+ GV I + +F+ T G + +R + G+ +
Sbjct: 298 HVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITT--GSTDHVIRIYYLGSEVPEKI 355
Query: 855 HPLKRHKAKVKC--FCVAHDSSRVAVGCAD--QRIYLY 888
L+ H KV FC DS R G D RI+ Y
Sbjct: 356 AELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQY 393
Score = 43.6 bits (98), Expect = 0.005
Identities = 23/75 (30%), Positives = 36/75 (48%)
Query: 731 KILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDG 790
+IL H++ V CVA + + +G DD V I + DG L+ L H ++ + V +
Sbjct: 175 RILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYEN 234
Query: 791 NIFITGSQDGTVCTW 805
+ GS D V W
Sbjct: 235 TLIAAGSCDKVVRVW 249
Score = 43.6 bits (98), Expect = 0.005
Identities = 34/148 (22%), Positives = 62/148 (41%), Gaps = 16/148 (10%)
Query: 677 QLWHIMSNSKVHTFKGHSGSI----LCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK--- 729
++W + + + V +GHS SI C ++YL + D ++ W H +K
Sbjct: 247 RVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRD 306
Query: 730 --TKILEHIAP---VLCVAAIVNRSLVISGGDDSAVIITSLVDGA--LVTKLDHHRGSVT 782
K E P + C + + +G D + I L + +L+ H V
Sbjct: 307 RPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVV 366
Query: 783 SVKVIQDGNI--FITGSQDGTVCTWNVE 808
+V+ +G+ F++GS+DGT W +
Sbjct: 367 AVQFCNNGDSLRFVSGSRDGTARIWQYQ 394
Score = 41.5 bits (93), Expect = 0.021
Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 4/89 (4%)
Query: 952 STTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHI 1011
+T + LL + IS + V+ + L A+G +VRVW L T A L GH I
Sbjct: 208 ATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASI 267
Query: 1012 TCVTFSPN----NLLVLSGSEDRTVVVWQ 1036
T + F P+ N + S D T+ WQ
Sbjct: 268 TSIQFCPSTKGTNRYLTSTGADGTICFWQ 296
Score = 36.3 bits (80), Expect = 0.81
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + T +GHS I M V E+ + GS D V VW L T A + H
Sbjct: 205 KIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHS 264
Query: 737 APVLCVAAI-----VNRSLVISGGD 756
A + + NR L +G D
Sbjct: 265 ASITSIQFCPSTKGTNRYLTSTGAD 289
Score = 34.7 bits (76), Expect = 2.5
Identities = 17/80 (21%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Query: 1167 KLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVK 1226
K+ + ++GH V CVA + + ++ +GS DC + +W + +++ +
Sbjct: 171 KMHKRILGHLSSVYCVAFDRSGR-RIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMA 229
Query: 1227 VTGDGTIAVSCAEDKTLIIW 1246
V + T+ + + DK + +W
Sbjct: 230 VNYENTLIAAGSCDKVVRVW 249
>AL512504-2|CAI95143.1| 1802|Homo sapiens bromodomain and WD repeat
domain containing 3 protein.
Length = 1802
Score = 65.3 bits (152), Expect = 2e-09
Identities = 76/341 (22%), Positives = 137/341 (40%), Gaps = 35/341 (10%)
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLS 1025
L + C+ R G+ +G LV++W RL ATL GH I+ + + N L+ +
Sbjct: 180 LSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAA 239
Query: 1026 GSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGR---RAMSSDRARNV------HV 1076
GS D+ V VW L +P +GHS++I ++ + R ++S A HV
Sbjct: 240 GSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHV 299
Query: 1077 WLV---DSGIVLHSATGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
+ D + + P I + + D+ +RI+ L G + E
Sbjct: 300 KTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYL-GSEVPEKIAEL 358
Query: 1131 VSHAERITC--FALTADSQHVVTGSMDMSLKVWKLDGGKLSQV-------LVGHS----- 1176
SH +++ F DS V+GS D + ++W+ + + + G++
Sbjct: 359 ESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMTGNNLPSGE 418
Query: 1177 DIVTCVAVSIT----NKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV-TGDG 1231
D +T + V++ T V++ + L VW+ T +V ++ D
Sbjct: 419 DKITKLKVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQ 478
Query: 1232 TIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLGFQITSDC 1272
I +S D + IW+ RG + ++ + G DC
Sbjct: 479 RIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDC 519
Score = 57.2 bits (132), Expect = 4e-07
Identities = 57/242 (23%), Positives = 99/242 (40%), Gaps = 23/242 (9%)
Query: 983 SGCAR-GLVRVWQLSTH-RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN 1040
+GC+R G + H ++ + GH+ + CV F + + +GS+D V +W D
Sbjct: 153 TGCSRFGHIFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDG 212
Query: 1041 SPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI----- 1095
T +GHS+ I + + + + + V VW + + + G SASI
Sbjct: 213 RLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQF 272
Query: 1096 --DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAER------ITCFALTADSQ 1147
+Y + D ++ W + R V ER I+C + ++
Sbjct: 273 CPSTKGTNRYLTSTGADGTICFWQW-HVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGM 331
Query: 1148 HVVTGSMDMSLKVWKLDGGKLSQV--LVGHSDIVTCVAVSITN---KTQVVSGSWDCNLI 1202
+ TGS D ++++ L ++ L H+D V VAV N + VSGS D
Sbjct: 332 FITTGSTDHVIRIYYLGSEVPEKIAELESHTDKV--VAVQFCNNGDSLRFVSGSRDGTAR 389
Query: 1203 VW 1204
+W
Sbjct: 390 IW 391
Score = 56.8 bits (131), Expect = 5e-07
Identities = 56/218 (25%), Positives = 89/218 (40%), Gaps = 23/218 (10%)
Query: 692 GHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLV 751
GH S+ C+ R + + TGS+D V +W + + H A + +A +L+
Sbjct: 178 GHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLI 237
Query: 752 ISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKV---IQDGNIFITGS-QDGTVCTWNV 807
+G D V + L A V L H S+TS++ + N ++T + DGT+C W
Sbjct: 238 AAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQW 297
Query: 808 ENFTL---------LSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGT----YL 854
T+ GV I + +F+ T G + +R + G+ +
Sbjct: 298 HVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITT--GSTDHVIRIYYLGSEVPEKI 355
Query: 855 HPLKRHKAKVKC--FCVAHDSSRVAVGCAD--QRIYLY 888
L+ H KV FC DS R G D RI+ Y
Sbjct: 356 AELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQY 393
Score = 43.6 bits (98), Expect = 0.005
Identities = 23/75 (30%), Positives = 36/75 (48%)
Query: 731 KILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDG 790
+IL H++ V CVA + + +G DD V I + DG L+ L H ++ + V +
Sbjct: 175 RILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYEN 234
Query: 791 NIFITGSQDGTVCTW 805
+ GS D V W
Sbjct: 235 TLIAAGSCDKVVRVW 249
Score = 43.6 bits (98), Expect = 0.005
Identities = 34/148 (22%), Positives = 62/148 (41%), Gaps = 16/148 (10%)
Query: 677 QLWHIMSNSKVHTFKGHSGSI----LCMCVTRESQYLLTGSEDTSVIVWDLHTLAVK--- 729
++W + + + V +GHS SI C ++YL + D ++ W H +K
Sbjct: 247 RVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRD 306
Query: 730 --TKILEHIAP---VLCVAAIVNRSLVISGGDDSAVIITSLVDGA--LVTKLDHHRGSVT 782
K E P + C + + +G D + I L + +L+ H V
Sbjct: 307 RPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVV 366
Query: 783 SVKVIQDGNI--FITGSQDGTVCTWNVE 808
+V+ +G+ F++GS+DGT W +
Sbjct: 367 AVQFCNNGDSLRFVSGSRDGTARIWQYQ 394
Score = 41.5 bits (93), Expect = 0.021
Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 4/89 (4%)
Query: 952 STTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHI 1011
+T + LL + IS + V+ + L A+G +VRVW L T A L GH I
Sbjct: 208 ATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASI 267
Query: 1012 TCVTFSPN----NLLVLSGSEDRTVVVWQ 1036
T + F P+ N + S D T+ WQ
Sbjct: 268 TSIQFCPSTKGTNRYLTSTGADGTICFWQ 296
Score = 36.3 bits (80), Expect = 0.81
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + T +GHS I M V E+ + GS D V VW L T A + H
Sbjct: 205 KIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHS 264
Query: 737 APVLCVAAI-----VNRSLVISGGD 756
A + + NR L +G D
Sbjct: 265 ASITSIQFCPSTKGTNRYLTSTGAD 289
Score = 34.7 bits (76), Expect = 2.5
Identities = 17/80 (21%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Query: 1167 KLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVK 1226
K+ + ++GH V CVA + + ++ +GS DC + +W + +++ +
Sbjct: 171 KMHKRILGHLSSVYCVAFDRSGR-RIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMA 229
Query: 1227 VTGDGTIAVSCAEDKTLIIW 1246
V + T+ + + DK + +W
Sbjct: 230 VNYENTLIAAGSCDKVVRVW 249
>AK027854-1|BAB55412.1| 504|Homo sapiens protein ( Homo sapiens cDNA
FLJ14948 fis, clone PLACE2000164, weakly similar to TIPD
PROTEIN. ).
Length = 504
Score = 65.3 bits (152), Expect = 2e-09
Identities = 52/218 (23%), Positives = 91/218 (41%), Gaps = 8/218 (3%)
Query: 991 RVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
R+W + +RL+ TL GH G + F +N ++SGS DRT+ +W L T S
Sbjct: 288 RIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGS 347
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH--SATGPSASIDVTLNMKYAVLSD 1108
S ++ + MS + + W + S ++ G ++D+ +
Sbjct: 348 SCND---IVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCS 404
Query: 1109 GDNSVRIWSL-AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK 1167
D+ +++ L + T + D +V GS + SL +W + GK
Sbjct: 405 RDDLLKVIDLRTNAIKQTFSATGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGK 464
Query: 1168 LSQVL-VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
+ +VL HS + VA S + + VVS C ++W
Sbjct: 465 VEKVLSKQHSSSINAVAWS-PSGSHVVSVDKGCKAVLW 501
Score = 61.3 bits (142), Expect = 2e-08
Identities = 57/284 (20%), Positives = 112/284 (39%), Gaps = 10/284 (3%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ--ATLNGHIGHITCVTFSPNNLLVLSG 1026
++ + S +L A+G V++W++ + + +L+G IT + F +L+
Sbjct: 222 VNAAQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAA 281
Query: 1027 SEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH 1086
S D +W + D T GHS + + + D R +S R + +W + S + +
Sbjct: 282 SNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIK 341
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
+ S+ D+ + + D +R W + SE R + +IT L +
Sbjct: 342 TVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDI----RSESIVREMELLGKITALDLNPER 397
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVL--VGHSDIVTCVAVSIT-NKTQVVSGSWDCNLIV 1203
+++ S D LKV L + Q G V + + + V +GS + +L +
Sbjct: 398 TELLSCSRDDLLKVIDLRTNAIKQTFSATGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYI 457
Query: 1204 WDINT-XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
W + T + V + G+ VS + ++W
Sbjct: 458 WSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 501
Score = 60.9 bits (141), Expect = 3e-08
Identities = 65/297 (21%), Positives = 121/297 (40%), Gaps = 23/297 (7%)
Query: 1005 NGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSL--TYKGHSSAIQTLLMMSDG 1062
+ H G + FSP + L+ +G DR V +W++ + G ++ I ++ S G
Sbjct: 216 DAHDGEVNAAQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAG 275
Query: 1063 RRAMSSDRARNVHVWLVDSGIVLHSATGPSA---SIDVTLNMKYAVLSDGDNSVRIWSLA 1119
+++ +W VD + H+ TG S S L+ V D ++++W L
Sbjct: 276 SYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDL- 334
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV 1179
S+ ++V +C + Q V++G D ++ W + S+ +V +++
Sbjct: 335 ---RSKVCIKTVFAGS--SCNDIVCTEQCVMSGHFDKKIRFWDI----RSESIVREMELL 385
Query: 1180 TCVAVSITN--KTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKV----TCVKVTGDGTI 1233
+ N +T+++S S D L V D+ T K T V + DG+
Sbjct: 386 GKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSATGFKCGSDWTRVVFSPDGSY 445
Query: 1234 AVSCAEDKTLIIWETKRGLALTSFS-LHVPLLGFQITSDCARVVVHLLDRGCLPIIW 1289
+ + + +L IW G S H + S VV +D+GC ++W
Sbjct: 446 VAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVS-VDKGCKAVLW 501
Score = 47.6 bits (108), Expect = 3e-04
Identities = 34/132 (25%), Positives = 57/132 (43%), Gaps = 2/132 (1%)
Query: 690 FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL--HTLAVKTKILEHIAPVLCVAAIVN 747
F H G + + S+ L TG D V +W++ K + A + +
Sbjct: 215 FDAHDGEVNAAQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSA 274
Query: 748 RSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
S +++ +D A I ++ D L L H G V S K + D ++GS D T+ W++
Sbjct: 275 GSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDL 334
Query: 808 ENFTLLSTVTAG 819
+ + TV AG
Sbjct: 335 RSKVCIKTVFAG 346
Score = 45.2 bits (102), Expect = 0.002
Identities = 32/161 (19%), Positives = 73/161 (45%), Gaps = 4/161 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
++ +G +L+ A + ++W + HT GHSG +L ++ +++GS D +
Sbjct: 269 IEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRT 328
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ +WDL + K I A C + V+SG D + + ++V +++
Sbjct: 329 LKLWDLRS---KVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREME-L 384
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA 818
G +T++ + + ++ S+D + ++ + T +A
Sbjct: 385 LGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSA 425
Score = 37.5 bits (83), Expect = 0.35
Identities = 34/129 (26%), Positives = 48/129 (37%), Gaps = 7/129 (5%)
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV-----ENFTLLSTVTAGVPIHIFDVTD 829
D H G V + + + TG D V W V E LS AG+ FD
Sbjct: 216 DAHDGEVNAAQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAG 275
Query: 830 DNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
+LL D + T H L H KV D++R+ G D+ + L+
Sbjct: 276 S--YLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 333
Query: 890 LHSAQLLRT 898
L S ++T
Sbjct: 334 LRSKVCIKT 342
Score = 37.5 bits (83), Expect = 0.35
Identities = 44/238 (18%), Positives = 93/238 (39%), Gaps = 9/238 (3%)
Query: 659 QLAPSGQHLVLAPSAGDPQLWHIMSNSKVH--TFKGHSGSILCMCVTRESQYLLTGSEDT 716
Q +P + L +LW + + G + I + YLL S D
Sbjct: 226 QFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDF 285
Query: 717 SVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH 776
+ +W + ++ + H VL +++ + ++SG D + + L + +
Sbjct: 286 ASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTV-- 343
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
GS + ++ ++G D + W++ + +++ + I D+ + LL+
Sbjct: 344 FAGSSCN-DIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLS 402
Query: 837 LQGDNEL---HLRT-FITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
D+ L LRT I T+ + + + D S VA G A+ +Y++S+
Sbjct: 403 CSRDDLLKVIDLRTNAIKQTFSATGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSV 460
>EF079890-1|ABN48555.1| 444|Homo sapiens ATG16 autophagy related
16-like protein 1 protein.
Length = 444
Score = 64.9 bits (151), Expect = 2e-09
Identities = 52/218 (23%), Positives = 91/218 (41%), Gaps = 8/218 (3%)
Query: 991 RVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
R+W + +RL+ TL GH G + F +N ++SGS DRT+ +W L T S
Sbjct: 228 RIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGS 287
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH--SATGPSASIDVTLNMKYAVLSD 1108
S ++ + MS + + W + S ++ G ++D+ +
Sbjct: 288 SCND---IVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCS 344
Query: 1109 GDNSVRIWSL-AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK 1167
D+ +++ L + T + D +V GS + SL +W + GK
Sbjct: 345 RDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGK 404
Query: 1168 LSQVL-VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
+ +VL HS + VA S + + VVS C ++W
Sbjct: 405 VEKVLSKQHSSSINAVAWS-PSGSHVVSVDKGCKAVLW 441
Score = 61.7 bits (143), Expect = 2e-08
Identities = 66/297 (22%), Positives = 122/297 (41%), Gaps = 23/297 (7%)
Query: 1005 NGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSL--TYKGHSSAIQTLLMMSDG 1062
+ H G + V FSP + L+ +G DR V +W++ + G ++ I ++ S G
Sbjct: 156 DAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAG 215
Query: 1063 RRAMSSDRARNVHVWLVDSGIVLHSATGPSA---SIDVTLNMKYAVLSDGDNSVRIWSLA 1119
+++ +W VD + H+ TG S S L+ V D ++++W L
Sbjct: 216 SYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDL- 274
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV 1179
S+ ++V +C + Q V++G D ++ W + S+ +V +++
Sbjct: 275 ---RSKVCIKTVFAGS--SCNDIVCTEQCVMSGHFDKKIRFWDI----RSESIVREMELL 325
Query: 1180 TCVAVSITN--KTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKV----TCVKVTGDGTI 1233
+ N +T+++S S D L V D+ T K T V + DG+
Sbjct: 326 GKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSY 385
Query: 1234 AVSCAEDKTLIIWETKRGLALTSFS-LHVPLLGFQITSDCARVVVHLLDRGCLPIIW 1289
+ + + +L IW G S H + S VV +D+GC ++W
Sbjct: 386 VAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVS-VDKGCKAVLW 441
Score = 61.7 bits (143), Expect = 2e-08
Identities = 58/285 (20%), Positives = 113/285 (39%), Gaps = 12/285 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ--ATLNGHIGHITCVTFSPNNLLVLSG 1026
++ ++ S +L A+G V++W++ + + +L+G IT + F +L+
Sbjct: 162 VNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAA 221
Query: 1027 SEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH 1086
S D +W + D T GHS + + + D R +S R + +W + S + +
Sbjct: 222 SNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIK 281
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
+ S+ D+ + + D +R W + SE R + +IT L +
Sbjct: 282 TVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDI----RSESIVREMELLGKITALDLNPER 337
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGH----SDIVTCVAVSITNKTQVVSGSWDCNLI 1202
+++ S D LKV L + Q T V S + + V +GS + +L
Sbjct: 338 TELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFS-PDGSYVAAGSAEGSLY 396
Query: 1203 VWDINT-XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
+W + T + V + G+ VS + ++W
Sbjct: 397 IWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 441
Score = 48.4 bits (110), Expect = 2e-04
Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 2/132 (1%)
Query: 690 FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL--HTLAVKTKILEHIAPVLCVAAIVN 747
F H G + + + S+ L TG D V +W++ K + A + +
Sbjct: 155 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSA 214
Query: 748 RSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
S +++ +D A I ++ D L L H G V S K + D ++GS D T+ W++
Sbjct: 215 GSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDL 274
Query: 808 ENFTLLSTVTAG 819
+ + TV AG
Sbjct: 275 RSKVCIKTVFAG 286
Score = 45.2 bits (102), Expect = 0.002
Identities = 32/161 (19%), Positives = 73/161 (45%), Gaps = 4/161 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
++ +G +L+ A + ++W + HT GHSG +L ++ +++GS D +
Sbjct: 209 IEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRT 268
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ +WDL + K I A C + V+SG D + + ++V +++
Sbjct: 269 LKLWDLRS---KVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREME-L 324
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA 818
G +T++ + + ++ S+D + ++ + T +A
Sbjct: 325 LGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSA 365
Score = 41.1 bits (92), Expect = 0.028
Identities = 45/239 (18%), Positives = 95/239 (39%), Gaps = 9/239 (3%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVH--TFKGHSGSILCMCVTRESQYLLTGSED 715
+Q +P + L +LW + + G + I + YLL S D
Sbjct: 165 VQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASND 224
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
+ +W + ++ + H VL +++ + ++SG D + + L + +
Sbjct: 225 FASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTV- 283
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLL 835
GS + ++ ++G D + W++ + +++ + I D+ + LL
Sbjct: 284 -FAGSSCN-DIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELL 341
Query: 836 TLQGDNEL---HLRT-FITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ D+ L LRT I T+ P + + + D S VA G A+ +Y++S+
Sbjct: 342 SCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSV 400
Score = 39.1 bits (87), Expect = 0.11
Identities = 35/129 (27%), Positives = 49/129 (37%), Gaps = 7/129 (5%)
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV-----ENFTLLSTVTAGVPIHIFDVTD 829
D H G V +V+ + TG D V W V E LS AG+ FD
Sbjct: 156 DAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAG 215
Query: 830 DNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
+LL D + T H L H KV D++R+ G D+ + L+
Sbjct: 216 S--YLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 273
Query: 890 LHSAQLLRT 898
L S ++T
Sbjct: 274 LRSKVCIKT 282
>EF079889-1|ABN48554.1| 588|Homo sapiens ATG16 autophagy related
16-like protein 1 protein.
Length = 588
Score = 64.9 bits (151), Expect = 2e-09
Identities = 52/218 (23%), Positives = 91/218 (41%), Gaps = 8/218 (3%)
Query: 991 RVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
R+W + +RL+ TL GH G + F +N ++SGS DRT+ +W L T S
Sbjct: 372 RIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGS 431
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH--SATGPSASIDVTLNMKYAVLSD 1108
S ++ + MS + + W + S ++ G ++D+ +
Sbjct: 432 SCND---IVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCS 488
Query: 1109 GDNSVRIWSL-AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK 1167
D+ +++ L + T + D +V GS + SL +W + GK
Sbjct: 489 RDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGK 548
Query: 1168 LSQVL-VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
+ +VL HS + VA S + + VVS C ++W
Sbjct: 549 VEKVLSKQHSSSINAVAWS-PSGSHVVSVDKGCKAVLW 585
Score = 61.7 bits (143), Expect = 2e-08
Identities = 66/297 (22%), Positives = 122/297 (41%), Gaps = 23/297 (7%)
Query: 1005 NGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSL--TYKGHSSAIQTLLMMSDG 1062
+ H G + V FSP + L+ +G DR V +W++ + G ++ I ++ S G
Sbjct: 300 DAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAG 359
Query: 1063 RRAMSSDRARNVHVWLVDSGIVLHSATGPSA---SIDVTLNMKYAVLSDGDNSVRIWSLA 1119
+++ +W VD + H+ TG S S L+ V D ++++W L
Sbjct: 360 SYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDL- 418
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV 1179
S+ ++V +C + Q V++G D ++ W + S+ +V +++
Sbjct: 419 ---RSKVCIKTVFAGS--SCNDIVCTEQCVMSGHFDKKIRFWDI----RSESIVREMELL 469
Query: 1180 TCVAVSITN--KTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKV----TCVKVTGDGTI 1233
+ N +T+++S S D L V D+ T K T V + DG+
Sbjct: 470 GKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSY 529
Query: 1234 AVSCAEDKTLIIWETKRGLALTSFS-LHVPLLGFQITSDCARVVVHLLDRGCLPIIW 1289
+ + + +L IW G S H + S VV +D+GC ++W
Sbjct: 530 VAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVS-VDKGCKAVLW 585
Score = 61.7 bits (143), Expect = 2e-08
Identities = 58/285 (20%), Positives = 113/285 (39%), Gaps = 12/285 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ--ATLNGHIGHITCVTFSPNNLLVLSG 1026
++ ++ S +L A+G V++W++ + + +L+G IT + F +L+
Sbjct: 306 VNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAA 365
Query: 1027 SEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH 1086
S D +W + D T GHS + + + D R +S R + +W + S + +
Sbjct: 366 SNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIK 425
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
+ S+ D+ + + D +R W + SE R + +IT L +
Sbjct: 426 TVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDI----RSESIVREMELLGKITALDLNPER 481
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGH----SDIVTCVAVSITNKTQVVSGSWDCNLI 1202
+++ S D LKV L + Q T V S + + V +GS + +L
Sbjct: 482 TELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFS-PDGSYVAAGSAEGSLY 540
Query: 1203 VWDINT-XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
+W + T + V + G+ VS + ++W
Sbjct: 541 IWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 585
Score = 48.4 bits (110), Expect = 2e-04
Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 2/132 (1%)
Query: 690 FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL--HTLAVKTKILEHIAPVLCVAAIVN 747
F H G + + + S+ L TG D V +W++ K + A + +
Sbjct: 299 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSA 358
Query: 748 RSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
S +++ +D A I ++ D L L H G V S K + D ++GS D T+ W++
Sbjct: 359 GSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDL 418
Query: 808 ENFTLLSTVTAG 819
+ + TV AG
Sbjct: 419 RSKVCIKTVFAG 430
Score = 45.2 bits (102), Expect = 0.002
Identities = 32/161 (19%), Positives = 73/161 (45%), Gaps = 4/161 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
++ +G +L+ A + ++W + HT GHSG +L ++ +++GS D +
Sbjct: 353 IEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRT 412
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ +WDL + K I A C + V+SG D + + ++V +++
Sbjct: 413 LKLWDLRS---KVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREME-L 468
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA 818
G +T++ + + ++ S+D + ++ + T +A
Sbjct: 469 LGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSA 509
Score = 41.1 bits (92), Expect = 0.028
Identities = 45/239 (18%), Positives = 95/239 (39%), Gaps = 9/239 (3%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVH--TFKGHSGSILCMCVTRESQYLLTGSED 715
+Q +P + L +LW + + G + I + YLL S D
Sbjct: 309 VQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASND 368
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
+ +W + ++ + H VL +++ + ++SG D + + L + +
Sbjct: 369 FASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTV- 427
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLL 835
GS + ++ ++G D + W++ + +++ + I D+ + LL
Sbjct: 428 -FAGSSCN-DIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELL 485
Query: 836 TLQGDNEL---HLRT-FITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ D+ L LRT I T+ P + + + D S VA G A+ +Y++S+
Sbjct: 486 SCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSV 544
Score = 39.1 bits (87), Expect = 0.11
Identities = 35/129 (27%), Positives = 49/129 (37%), Gaps = 7/129 (5%)
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV-----ENFTLLSTVTAGVPIHIFDVTD 829
D H G V +V+ + TG D V W V E LS AG+ FD
Sbjct: 300 DAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAG 359
Query: 830 DNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
+LL D + T H L H KV D++R+ G D+ + L+
Sbjct: 360 S--YLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 417
Query: 890 LHSAQLLRT 898
L S ++T
Sbjct: 418 LRSKVCIKT 426
>BC117337-1|AAI17338.1| 523|Homo sapiens ATG16L1 protein protein.
Length = 523
Score = 64.9 bits (151), Expect = 2e-09
Identities = 52/218 (23%), Positives = 91/218 (41%), Gaps = 8/218 (3%)
Query: 991 RVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
R+W + +RL+ TL GH G + F +N ++SGS DRT+ +W L T S
Sbjct: 307 RIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGS 366
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH--SATGPSASIDVTLNMKYAVLSD 1108
S ++ + MS + + W + S ++ G ++D+ +
Sbjct: 367 SCND---IVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCS 423
Query: 1109 GDNSVRIWSL-AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK 1167
D+ +++ L + T + D +V GS + SL +W + GK
Sbjct: 424 RDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGK 483
Query: 1168 LSQVL-VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
+ +VL HS + VA S + + VVS C ++W
Sbjct: 484 VEKVLSKQHSSSINAVAWS-PSGSHVVSVDKGCKAVLW 520
Score = 61.7 bits (143), Expect = 2e-08
Identities = 66/297 (22%), Positives = 122/297 (41%), Gaps = 23/297 (7%)
Query: 1005 NGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSL--TYKGHSSAIQTLLMMSDG 1062
+ H G + V FSP + L+ +G DR V +W++ + G ++ I ++ S G
Sbjct: 235 DAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAG 294
Query: 1063 RRAMSSDRARNVHVWLVDSGIVLHSATGPSA---SIDVTLNMKYAVLSDGDNSVRIWSLA 1119
+++ +W VD + H+ TG S S L+ V D ++++W L
Sbjct: 295 SYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDL- 353
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV 1179
S+ ++V +C + Q V++G D ++ W + S+ +V +++
Sbjct: 354 ---RSKVCIKTVFAGS--SCNDIVCTEQCVMSGHFDKKIRFWDI----RSESIVREMELL 404
Query: 1180 TCVAVSITN--KTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKV----TCVKVTGDGTI 1233
+ N +T+++S S D L V D+ T K T V + DG+
Sbjct: 405 GKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSY 464
Query: 1234 AVSCAEDKTLIIWETKRGLALTSFS-LHVPLLGFQITSDCARVVVHLLDRGCLPIIW 1289
+ + + +L IW G S H + S VV +D+GC ++W
Sbjct: 465 VAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVS-VDKGCKAVLW 520
Score = 61.7 bits (143), Expect = 2e-08
Identities = 58/285 (20%), Positives = 113/285 (39%), Gaps = 12/285 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ--ATLNGHIGHITCVTFSPNNLLVLSG 1026
++ ++ S +L A+G V++W++ + + +L+G IT + F +L+
Sbjct: 241 VNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAA 300
Query: 1027 SEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH 1086
S D +W + D T GHS + + + D R +S R + +W + S + +
Sbjct: 301 SNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIK 360
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
+ S+ D+ + + D +R W + SE R + +IT L +
Sbjct: 361 TVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDI----RSESIVREMELLGKITALDLNPER 416
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGH----SDIVTCVAVSITNKTQVVSGSWDCNLI 1202
+++ S D LKV L + Q T V S + + V +GS + +L
Sbjct: 417 TELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFS-PDGSYVAAGSAEGSLY 475
Query: 1203 VWDINT-XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
+W + T + V + G+ VS + ++W
Sbjct: 476 IWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 520
Score = 48.4 bits (110), Expect = 2e-04
Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 2/132 (1%)
Query: 690 FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL--HTLAVKTKILEHIAPVLCVAAIVN 747
F H G + + + S+ L TG D V +W++ K + A + +
Sbjct: 234 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSA 293
Query: 748 RSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
S +++ +D A I ++ D L L H G V S K + D ++GS D T+ W++
Sbjct: 294 GSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDL 353
Query: 808 ENFTLLSTVTAG 819
+ + TV AG
Sbjct: 354 RSKVCIKTVFAG 365
Score = 45.2 bits (102), Expect = 0.002
Identities = 32/161 (19%), Positives = 73/161 (45%), Gaps = 4/161 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
++ +G +L+ A + ++W + HT GHSG +L ++ +++GS D +
Sbjct: 288 IEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRT 347
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ +WDL + K I A C + V+SG D + + ++V +++
Sbjct: 348 LKLWDLRS---KVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREME-L 403
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA 818
G +T++ + + ++ S+D + ++ + T +A
Sbjct: 404 LGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSA 444
Score = 41.1 bits (92), Expect = 0.028
Identities = 45/239 (18%), Positives = 95/239 (39%), Gaps = 9/239 (3%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVH--TFKGHSGSILCMCVTRESQYLLTGSED 715
+Q +P + L +LW + + G + I + YLL S D
Sbjct: 244 VQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASND 303
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
+ +W + ++ + H VL +++ + ++SG D + + L + +
Sbjct: 304 FASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTV- 362
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLL 835
GS + ++ ++G D + W++ + +++ + I D+ + LL
Sbjct: 363 -FAGSSCN-DIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELL 420
Query: 836 TLQGDNEL---HLRT-FITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ D+ L LRT I T+ P + + + D S VA G A+ +Y++S+
Sbjct: 421 SCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSV 479
Score = 39.1 bits (87), Expect = 0.11
Identities = 35/129 (27%), Positives = 49/129 (37%), Gaps = 7/129 (5%)
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV-----ENFTLLSTVTAGVPIHIFDVTD 829
D H G V +V+ + TG D V W V E LS AG+ FD
Sbjct: 235 DAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAG 294
Query: 830 DNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
+LL D + T H L H KV D++R+ G D+ + L+
Sbjct: 295 S--YLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 352
Query: 890 LHSAQLLRT 898
L S ++T
Sbjct: 353 LRSKVCIKT 361
>BC071846-1|AAH71846.1| 475|Homo sapiens ATG16L1 protein protein.
Length = 475
Score = 64.9 bits (151), Expect = 2e-09
Identities = 52/218 (23%), Positives = 91/218 (41%), Gaps = 8/218 (3%)
Query: 991 RVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
R+W + +RL+ TL GH G + F +N ++SGS DRT+ +W L T S
Sbjct: 259 RIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGS 318
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH--SATGPSASIDVTLNMKYAVLSD 1108
S ++ + MS + + W + S ++ G ++D+ +
Sbjct: 319 SCND---IVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCS 375
Query: 1109 GDNSVRIWSL-AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK 1167
D+ +++ L + T + D +V GS + SL +W + GK
Sbjct: 376 RDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGK 435
Query: 1168 LSQVL-VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
+ +VL HS + VA S + + VVS C ++W
Sbjct: 436 VEKVLSKQHSSSINAVAWS-PSGSHVVSVDKGCKAVLW 472
Score = 61.7 bits (143), Expect = 2e-08
Identities = 66/297 (22%), Positives = 122/297 (41%), Gaps = 23/297 (7%)
Query: 1005 NGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSL--TYKGHSSAIQTLLMMSDG 1062
+ H G + V FSP + L+ +G DR V +W++ + G ++ I ++ S G
Sbjct: 187 DAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAG 246
Query: 1063 RRAMSSDRARNVHVWLVDSGIVLHSATGPSA---SIDVTLNMKYAVLSDGDNSVRIWSLA 1119
+++ +W VD + H+ TG S S L+ V D ++++W L
Sbjct: 247 SYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDL- 305
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV 1179
S+ ++V +C + Q V++G D ++ W + S+ +V +++
Sbjct: 306 ---RSKVCIKTVFAGS--SCNDIVCTEQCVMSGHFDKKIRFWDI----RSESIVREMELL 356
Query: 1180 TCVAVSITN--KTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKV----TCVKVTGDGTI 1233
+ N +T+++S S D L V D+ T K T V + DG+
Sbjct: 357 GKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSY 416
Query: 1234 AVSCAEDKTLIIWETKRGLALTSFS-LHVPLLGFQITSDCARVVVHLLDRGCLPIIW 1289
+ + + +L IW G S H + S VV +D+GC ++W
Sbjct: 417 VAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVS-VDKGCKAVLW 472
Score = 61.7 bits (143), Expect = 2e-08
Identities = 58/285 (20%), Positives = 113/285 (39%), Gaps = 12/285 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ--ATLNGHIGHITCVTFSPNNLLVLSG 1026
++ ++ S +L A+G V++W++ + + +L+G IT + F +L+
Sbjct: 193 VNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAA 252
Query: 1027 SEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH 1086
S D +W + D T GHS + + + D R +S R + +W + S + +
Sbjct: 253 SNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIK 312
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
+ S+ D+ + + D +R W + SE R + +IT L +
Sbjct: 313 TVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDI----RSESIVREMELLGKITALDLNPER 368
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGH----SDIVTCVAVSITNKTQVVSGSWDCNLI 1202
+++ S D LKV L + Q T V S + + V +GS + +L
Sbjct: 369 TELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFS-PDGSYVAAGSAEGSLY 427
Query: 1203 VWDINT-XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
+W + T + V + G+ VS + ++W
Sbjct: 428 IWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 472
Score = 48.4 bits (110), Expect = 2e-04
Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 2/132 (1%)
Query: 690 FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL--HTLAVKTKILEHIAPVLCVAAIVN 747
F H G + + + S+ L TG D V +W++ K + A + +
Sbjct: 186 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSA 245
Query: 748 RSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
S +++ +D A I ++ D L L H G V S K + D ++GS D T+ W++
Sbjct: 246 GSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDL 305
Query: 808 ENFTLLSTVTAG 819
+ + TV AG
Sbjct: 306 RSKVCIKTVFAG 317
Score = 45.2 bits (102), Expect = 0.002
Identities = 32/161 (19%), Positives = 73/161 (45%), Gaps = 4/161 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
++ +G +L+ A + ++W + HT GHSG +L ++ +++GS D +
Sbjct: 240 IEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRT 299
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ +WDL + K I A C + V+SG D + + ++V +++
Sbjct: 300 LKLWDLRS---KVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREME-L 355
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA 818
G +T++ + + ++ S+D + ++ + T +A
Sbjct: 356 LGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSA 396
Score = 41.1 bits (92), Expect = 0.028
Identities = 45/239 (18%), Positives = 95/239 (39%), Gaps = 9/239 (3%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVH--TFKGHSGSILCMCVTRESQYLLTGSED 715
+Q +P + L +LW + + G + I + YLL S D
Sbjct: 196 VQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASND 255
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
+ +W + ++ + H VL +++ + ++SG D + + L + +
Sbjct: 256 FASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTV- 314
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLL 835
GS + ++ ++G D + W++ + +++ + I D+ + LL
Sbjct: 315 -FAGSSCN-DIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELL 372
Query: 836 TLQGDNEL---HLRT-FITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ D+ L LRT I T+ P + + + D S VA G A+ +Y++S+
Sbjct: 373 SCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSV 431
Score = 39.1 bits (87), Expect = 0.11
Identities = 35/129 (27%), Positives = 49/129 (37%), Gaps = 7/129 (5%)
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV-----ENFTLLSTVTAGVPIHIFDVTD 829
D H G V +V+ + TG D V W V E LS AG+ FD
Sbjct: 187 DAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAG 246
Query: 830 DNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
+LL D + T H L H KV D++R+ G D+ + L+
Sbjct: 247 S--YLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 304
Query: 890 LHSAQLLRT 898
L S ++T
Sbjct: 305 LRSKVCIKT 313
>AY398617-1|AAR32130.1| 607|Homo sapiens APG16L beta protein.
Length = 607
Score = 64.9 bits (151), Expect = 2e-09
Identities = 52/218 (23%), Positives = 91/218 (41%), Gaps = 8/218 (3%)
Query: 991 RVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
R+W + +RL+ TL GH G + F +N ++SGS DRT+ +W L T S
Sbjct: 391 RIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGS 450
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH--SATGPSASIDVTLNMKYAVLSD 1108
S ++ + MS + + W + S ++ G ++D+ +
Sbjct: 451 SCND---IVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCS 507
Query: 1109 GDNSVRIWSL-AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK 1167
D+ +++ L + T + D +V GS + SL +W + GK
Sbjct: 508 RDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGK 567
Query: 1168 LSQVL-VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
+ +VL HS + VA S + + VVS C ++W
Sbjct: 568 VEKVLSKQHSSSINAVAWS-PSGSHVVSVDKGCKAVLW 604
Score = 61.7 bits (143), Expect = 2e-08
Identities = 66/297 (22%), Positives = 122/297 (41%), Gaps = 23/297 (7%)
Query: 1005 NGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSL--TYKGHSSAIQTLLMMSDG 1062
+ H G + V FSP + L+ +G DR V +W++ + G ++ I ++ S G
Sbjct: 319 DAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAG 378
Query: 1063 RRAMSSDRARNVHVWLVDSGIVLHSATGPSA---SIDVTLNMKYAVLSDGDNSVRIWSLA 1119
+++ +W VD + H+ TG S S L+ V D ++++W L
Sbjct: 379 SYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDL- 437
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV 1179
S+ ++V +C + Q V++G D ++ W + S+ +V +++
Sbjct: 438 ---RSKVCIKTVFAGS--SCNDIVCTEQCVMSGHFDKKIRFWDI----RSESIVREMELL 488
Query: 1180 TCVAVSITN--KTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKV----TCVKVTGDGTI 1233
+ N +T+++S S D L V D+ T K T V + DG+
Sbjct: 489 GKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSY 548
Query: 1234 AVSCAEDKTLIIWETKRGLALTSFS-LHVPLLGFQITSDCARVVVHLLDRGCLPIIW 1289
+ + + +L IW G S H + S VV +D+GC ++W
Sbjct: 549 VAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVS-VDKGCKAVLW 604
Score = 61.7 bits (143), Expect = 2e-08
Identities = 58/285 (20%), Positives = 113/285 (39%), Gaps = 12/285 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ--ATLNGHIGHITCVTFSPNNLLVLSG 1026
++ ++ S +L A+G V++W++ + + +L+G IT + F +L+
Sbjct: 325 VNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAA 384
Query: 1027 SEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH 1086
S D +W + D T GHS + + + D R +S R + +W + S + +
Sbjct: 385 SNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIK 444
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
+ S+ D+ + + D +R W + SE R + +IT L +
Sbjct: 445 TVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDI----RSESIVREMELLGKITALDLNPER 500
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGH----SDIVTCVAVSITNKTQVVSGSWDCNLI 1202
+++ S D LKV L + Q T V S + + V +GS + +L
Sbjct: 501 TELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFS-PDGSYVAAGSAEGSLY 559
Query: 1203 VWDINT-XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
+W + T + V + G+ VS + ++W
Sbjct: 560 IWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 604
Score = 48.4 bits (110), Expect = 2e-04
Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 2/132 (1%)
Query: 690 FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL--HTLAVKTKILEHIAPVLCVAAIVN 747
F H G + + + S+ L TG D V +W++ K + A + +
Sbjct: 318 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSA 377
Query: 748 RSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
S +++ +D A I ++ D L L H G V S K + D ++GS D T+ W++
Sbjct: 378 GSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDL 437
Query: 808 ENFTLLSTVTAG 819
+ + TV AG
Sbjct: 438 RSKVCIKTVFAG 449
Score = 45.2 bits (102), Expect = 0.002
Identities = 32/161 (19%), Positives = 73/161 (45%), Gaps = 4/161 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
++ +G +L+ A + ++W + HT GHSG +L ++ +++GS D +
Sbjct: 372 IEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRT 431
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ +WDL + K I A C + V+SG D + + ++V +++
Sbjct: 432 LKLWDLRS---KVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREME-L 487
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA 818
G +T++ + + ++ S+D + ++ + T +A
Sbjct: 488 LGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSA 528
Score = 41.1 bits (92), Expect = 0.028
Identities = 45/239 (18%), Positives = 95/239 (39%), Gaps = 9/239 (3%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVH--TFKGHSGSILCMCVTRESQYLLTGSED 715
+Q +P + L +LW + + G + I + YLL S D
Sbjct: 328 VQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASND 387
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
+ +W + ++ + H VL +++ + ++SG D + + L + +
Sbjct: 388 FASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTV- 446
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLL 835
GS + ++ ++G D + W++ + +++ + I D+ + LL
Sbjct: 447 -FAGSSCN-DIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELL 504
Query: 836 TLQGDNEL---HLRT-FITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ D+ L LRT I T+ P + + + D S VA G A+ +Y++S+
Sbjct: 505 SCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSV 563
Score = 39.1 bits (87), Expect = 0.11
Identities = 35/129 (27%), Positives = 49/129 (37%), Gaps = 7/129 (5%)
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV-----ENFTLLSTVTAGVPIHIFDVTD 829
D H G V +V+ + TG D V W V E LS AG+ FD
Sbjct: 319 DAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAG 378
Query: 830 DNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
+LL D + T H L H KV D++R+ G D+ + L+
Sbjct: 379 S--YLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 436
Query: 890 LHSAQLLRT 898
L S ++T
Sbjct: 437 LRSKVCIKT 445
>AK123876-1|BAC85713.1| 428|Homo sapiens protein ( Homo sapiens cDNA
FLJ41882 fis, clone OCBBF2022351, weakly similar to TIPD
PROTEIN. ).
Length = 428
Score = 64.9 bits (151), Expect = 2e-09
Identities = 52/218 (23%), Positives = 91/218 (41%), Gaps = 8/218 (3%)
Query: 991 RVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
R+W + +RL+ TL GH G + F +N ++SGS DRT+ +W L T S
Sbjct: 212 RIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGS 271
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH--SATGPSASIDVTLNMKYAVLSD 1108
S ++ + MS + + W + S ++ G ++D+ +
Sbjct: 272 SCND---IVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCS 328
Query: 1109 GDNSVRIWSL-AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK 1167
D+ +++ L + T + D +V GS + SL +W + GK
Sbjct: 329 RDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGK 388
Query: 1168 LSQVL-VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
+ +VL HS + VA S + + VVS C ++W
Sbjct: 389 VEKVLSKQHSSSINAVAWS-PSGSHVVSVDKGCKAVLW 425
Score = 52.8 bits (121), Expect = 9e-06
Identities = 50/241 (20%), Positives = 91/241 (37%), Gaps = 10/241 (4%)
Query: 1011 ITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDR 1070
IT + F +L+ S D +W + D T GHS + + + D R +S
Sbjct: 190 ITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSH 249
Query: 1071 ARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRS 1130
R + +W + S + + + S+ D+ + + D +R W + SE R
Sbjct: 250 DRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDI----RSESIVRE 305
Query: 1131 VSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGH----SDIVTCVAVSI 1186
+ +IT L + +++ S D LKV L + Q T V S
Sbjct: 306 MELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFS- 364
Query: 1187 TNKTQVVSGSWDCNLIVWDINT-XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLII 1245
+ + V +GS + +L +W + T + V + G+ VS + ++
Sbjct: 365 PDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVL 424
Query: 1246 W 1246
W
Sbjct: 425 W 425
Score = 52.4 bits (120), Expect = 1e-05
Identities = 45/183 (24%), Positives = 80/183 (43%), Gaps = 12/183 (6%)
Query: 1094 SIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGS 1153
SI+ Y + + D + RIW++ D+ H+ ++ D+ +V+GS
Sbjct: 192 SIEFDSAGSYLLAASNDFASRIWTV---DDYRLRHTLTGHSGKVLSAKFLLDNARIVSGS 248
Query: 1154 MDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXX 1213
D +LK+W L + + S +C + T + V+SG +D + WDI +
Sbjct: 249 HDRTLKLWDLRSKVCIKTVFAGS---SCNDIVCTEQC-VMSGHFDKKIRFWDIRSESIVR 304
Query: 1214 XXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPLLGFQITSDCA 1273
K+T + + + T +SC+ D L + + + +FS P GF+ SD
Sbjct: 305 EMELLG-KITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFS--AP--GFKCGSDWT 359
Query: 1274 RVV 1276
RVV
Sbjct: 360 RVV 362
Score = 45.2 bits (102), Expect = 0.002
Identities = 32/161 (19%), Positives = 73/161 (45%), Gaps = 4/161 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
++ +G +L+ A + ++W + HT GHSG +L ++ +++GS D +
Sbjct: 193 IEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRT 252
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ +WDL + K I A C + V+SG D + + ++V +++
Sbjct: 253 LKLWDLRS---KVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREME-L 308
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA 818
G +T++ + + ++ S+D + ++ + T +A
Sbjct: 309 LGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSA 349
Score = 44.0 bits (99), Expect = 0.004
Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 1/87 (1%)
Query: 1122 DNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTC 1181
D + +V + IT + +++ S D + ++W +D +L L GHS V
Sbjct: 175 DAHDGEVNAVQFSPGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLS 234
Query: 1182 VAVSITNKTQVVSGSWDCNLIVWDINT 1208
+ N ++VSGS D L +WD+ +
Sbjct: 235 AKFLLDN-ARIVSGSHDRTLKLWDLRS 260
Score = 39.1 bits (87), Expect = 0.11
Identities = 22/71 (30%), Positives = 36/71 (50%)
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
S +++ +D A I ++ D L L H G V S K + D ++GS D T+ W++
Sbjct: 200 SYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLR 259
Query: 809 NFTLLSTVTAG 819
+ + TV AG
Sbjct: 260 SKVCIKTVFAG 270
Score = 35.5 bits (78), Expect = 1.4
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 975 SRDGQLGASGCARGLVRVWQLSTHRLQATLN-GHIGHITCVTFSPNNLLVLSGSEDRTVV 1033
S DG A+G A G + +W + T +++ L+ H I V +SP+ V+S + V
Sbjct: 364 SPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAV 423
Query: 1034 VW 1035
+W
Sbjct: 424 LW 425
>AC013726-3|AAY14860.1| 523|Homo sapiens unknown protein.
Length = 523
Score = 64.9 bits (151), Expect = 2e-09
Identities = 52/218 (23%), Positives = 91/218 (41%), Gaps = 8/218 (3%)
Query: 991 RVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHS 1050
R+W + +RL+ TL GH G + F +N ++SGS DRT+ +W L T S
Sbjct: 307 RIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGS 366
Query: 1051 SAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH--SATGPSASIDVTLNMKYAVLSD 1108
S ++ + MS + + W + S ++ G ++D+ +
Sbjct: 367 SCND---IVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCS 423
Query: 1109 GDNSVRIWSL-AGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGK 1167
D+ +++ L + T + D +V GS + SL +W + GK
Sbjct: 424 RDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGK 483
Query: 1168 LSQVL-VGHSDIVTCVAVSITNKTQVVSGSWDCNLIVW 1204
+ +VL HS + VA S + + VVS C ++W
Sbjct: 484 VEKVLSKQHSSSINAVAWS-PSGSHVVSVDKGCKAVLW 520
Score = 61.7 bits (143), Expect = 2e-08
Identities = 66/297 (22%), Positives = 122/297 (41%), Gaps = 23/297 (7%)
Query: 1005 NGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSL--TYKGHSSAIQTLLMMSDG 1062
+ H G + V FSP + L+ +G DR V +W++ + G ++ I ++ S G
Sbjct: 235 DAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAG 294
Query: 1063 RRAMSSDRARNVHVWLVDSGIVLHSATGPSA---SIDVTLNMKYAVLSDGDNSVRIWSLA 1119
+++ +W VD + H+ TG S S L+ V D ++++W L
Sbjct: 295 SYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDL- 353
Query: 1120 GGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV 1179
S+ ++V +C + Q V++G D ++ W + S+ +V +++
Sbjct: 354 ---RSKVCIKTVFAGS--SCNDIVCTEQCVMSGHFDKKIRFWDI----RSESIVREMELL 404
Query: 1180 TCVAVSITN--KTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKV----TCVKVTGDGTI 1233
+ N +T+++S S D L V D+ T K T V + DG+
Sbjct: 405 GKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSY 464
Query: 1234 AVSCAEDKTLIIWETKRGLALTSFS-LHVPLLGFQITSDCARVVVHLLDRGCLPIIW 1289
+ + + +L IW G S H + S VV +D+GC ++W
Sbjct: 465 VAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVS-VDKGCKAVLW 520
Score = 61.7 bits (143), Expect = 2e-08
Identities = 58/285 (20%), Positives = 113/285 (39%), Gaps = 12/285 (4%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQ--ATLNGHIGHITCVTFSPNNLLVLSG 1026
++ ++ S +L A+G V++W++ + + +L+G IT + F +L+
Sbjct: 241 VNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAA 300
Query: 1027 SEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLH 1086
S D +W + D T GHS + + + D R +S R + +W + S + +
Sbjct: 301 SNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIK 360
Query: 1087 SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
+ S+ D+ + + D +R W + SE R + +IT L +
Sbjct: 361 TVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDI----RSESIVREMELLGKITALDLNPER 416
Query: 1147 QHVVTGSMDMSLKVWKLDGGKLSQVLVGH----SDIVTCVAVSITNKTQVVSGSWDCNLI 1202
+++ S D LKV L + Q T V S + + V +GS + +L
Sbjct: 417 TELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFS-PDGSYVAAGSAEGSLY 475
Query: 1203 VWDINT-XXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
+W + T + V + G+ VS + ++W
Sbjct: 476 IWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 520
Score = 48.4 bits (110), Expect = 2e-04
Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 2/132 (1%)
Query: 690 FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDL--HTLAVKTKILEHIAPVLCVAAIVN 747
F H G + + + S+ L TG D V +W++ K + A + +
Sbjct: 234 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSA 293
Query: 748 RSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
S +++ +D A I ++ D L L H G V S K + D ++GS D T+ W++
Sbjct: 294 GSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDL 353
Query: 808 ENFTLLSTVTAG 819
+ + TV AG
Sbjct: 354 RSKVCIKTVFAG 365
Score = 45.2 bits (102), Expect = 0.002
Identities = 32/161 (19%), Positives = 73/161 (45%), Gaps = 4/161 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
++ +G +L+ A + ++W + HT GHSG +L ++ +++GS D +
Sbjct: 288 IEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRT 347
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ +WDL + K I A C + V+SG D + + ++V +++
Sbjct: 348 LKLWDLRS---KVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREME-L 403
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTA 818
G +T++ + + ++ S+D + ++ + T +A
Sbjct: 404 LGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSA 444
Score = 41.1 bits (92), Expect = 0.028
Identities = 45/239 (18%), Positives = 95/239 (39%), Gaps = 9/239 (3%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVH--TFKGHSGSILCMCVTRESQYLLTGSED 715
+Q +P + L +LW + + G + I + YLL S D
Sbjct: 244 VQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASND 303
Query: 716 TSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD 775
+ +W + ++ + H VL +++ + ++SG D + + L + +
Sbjct: 304 FASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTV- 362
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLL 835
GS + ++ ++G D + W++ + +++ + I D+ + LL
Sbjct: 363 -FAGSSCN-DIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELL 420
Query: 836 TLQGDNEL---HLRT-FITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ D+ L LRT I T+ P + + + D S VA G A+ +Y++S+
Sbjct: 421 SCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSV 479
Score = 39.1 bits (87), Expect = 0.11
Identities = 35/129 (27%), Positives = 49/129 (37%), Gaps = 7/129 (5%)
Query: 775 DHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV-----ENFTLLSTVTAGVPIHIFDVTD 829
D H G V +V+ + TG D V W V E LS AG+ FD
Sbjct: 235 DAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAG 294
Query: 830 DNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYS 889
+LL D + T H L H KV D++R+ G D+ + L+
Sbjct: 295 S--YLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 352
Query: 890 LHSAQLLRT 898
L S ++T
Sbjct: 353 LRSKVCIKT 361
>X95263-1|CAA64560.1| 919|Homo sapiens PWP2 protein.
Length = 919
Score = 63.7 bits (148), Expect = 5e-09
Identities = 65/317 (20%), Positives = 122/317 (38%), Gaps = 8/317 (2%)
Query: 941 PTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRL 1000
P ++ K + K + ++ D ++ + L +G A G+ + +L L
Sbjct: 263 PAEEEKTGKVKYSRLAKYFFNKEGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNL 322
Query: 1001 QATLNGHIGHITCVTFSPNNLLVLSGSEDR-TVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
+L+ I V + + + G ++VW+ S L +GH +++ L
Sbjct: 323 IHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYS 382
Query: 1060 SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMK-YAVL-SDGDNSVRIW 1116
DG+ ++ V VW SG + T S+ + VT Y V+ S D +VR +
Sbjct: 383 PDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 1117 SLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD-MSLKVWKLDGGKLSQVLVGH 1175
L N + + +C A+ A + V G+ D + VW + G+L VL GH
Sbjct: 443 DLHRYRNF--RTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGH 500
Query: 1176 SDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAV 1235
++ + + K+ + S SWD + +WD+ V DG
Sbjct: 501 EGPISGLCFN-PMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRPDGAELA 559
Query: 1236 SCAEDKTLIIWETKRGL 1252
+ + W+ + +
Sbjct: 560 VATLNSQITFWDPENAV 576
Score = 61.3 bits (142), Expect = 2e-08
Identities = 47/228 (20%), Positives = 90/228 (39%), Gaps = 4/228 (1%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS-VIVWDLHT 725
LV ++G L + + +H+ SI + + ++ G ++VW+ +
Sbjct: 303 LVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQS 362
Query: 726 LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVK 785
+ K H ++ +A + +++GGDD V + + + G H VT V
Sbjct: 363 ESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVT 422
Query: 786 VIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDD---NVFLLTLQGDNE 842
G + +T S DGTV +++ + T T+ P V D + Q E
Sbjct: 423 FTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFE 482
Query: 843 LHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ + + TG L L H+ + C S +A D+ + L+ +
Sbjct: 483 IFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 60.1 bits (139), Expect = 6e-08
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 2/152 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L +P GQ++V G ++W+ +S TF HS + + T ++T S D +
Sbjct: 379 LAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGT 438
Query: 718 VIVWDLHTLA-VKTKILEHIAPVLCVAAIVNRSLVISGGDDS-AVIITSLVDGALVTKLD 775
V +DLH +T CVA + +V +G DS + + S+ G L+ L
Sbjct: 439 VRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLS 498
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
H G ++ + ++ + S D TV W++
Sbjct: 499 GHEGPISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 48.8 bits (111), Expect = 1e-04
Identities = 35/130 (26%), Positives = 53/130 (40%), Gaps = 3/130 (2%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H + A + D Q++VTG D +KVW G HS VT V + T V
Sbjct: 372 HFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYV-V 430
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXX-XXXKVTCVKVTGDGTIAVSCAEDK-TLIIWETKR 1250
V+ S D + +D++ + +CV V G I + A+D + +W +
Sbjct: 431 VTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQT 490
Query: 1251 GLALTSFSLH 1260
G L S H
Sbjct: 491 GRLLDVLSGH 500
Score = 48.4 bits (110), Expect = 2e-04
Identities = 46/224 (20%), Positives = 89/224 (39%), Gaps = 8/224 (3%)
Query: 962 EQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNL 1021
+Q + L S DGQ +G G V+VW + T H +T VTF+
Sbjct: 369 QQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGY 428
Query: 1022 LVLSGSEDRTVVVWQLADNSPSLTYKG-HSSAIQTLLMMSDGR-RAMSSDRARNVHVWLV 1079
+V++ S D TV + L T+ + + + + G + + + + VW +
Sbjct: 429 VVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSM 488
Query: 1080 DSGIVLHSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAER 1136
+G +L +G I + N +VL+ D +VR+W + +++ S A
Sbjct: 489 QTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALA 548
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVT 1180
+T D + +++ + W + + + G D+ T
Sbjct: 549 VT---FRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKT 589
Score = 42.3 bits (95), Expect = 0.012
Identities = 41/168 (24%), Positives = 70/168 (41%), Gaps = 12/168 (7%)
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
+Y V D V++W+ G H+ +T TA VVT SMD +++ +
Sbjct: 386 QYIVTGGDDGKVKVWNTLSGFCFVT---FTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 1162 KLDGGKLSQVLVGHSDI-VTCVAVSITNKTQVVSGSWDC-NLIVWDINTXXXXXXXXXXX 1219
L + + +CVAV + + V +G+ D + VW + T
Sbjct: 443 DLHRYRNFRTFTSPRPTQFSCVAVDASGEI-VSAGAQDSFEIFVWSMQTGRLLDVLSGHE 501
Query: 1220 XKVTCVKVTGDGTIAVSCAEDKTLIIWE------TKRGLALTSFSLHV 1261
++ + ++ S + DKT+ +W+ TK LALTS +L V
Sbjct: 502 GPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAV 549
Score = 33.9 bits (74), Expect = 4.3
Identities = 54/205 (26%), Positives = 87/205 (42%), Gaps = 15/205 (7%)
Query: 1014 VTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARN 1073
+ F+ N V+S +R V V+ L +N ++ + + DGR A+ D +
Sbjct: 20 LNFTCNGNSVISPVGNR-VTVFDLKNNKSDTLPLATRYNVKCVGLSPDGRLAIIVDEGGD 78
Query: 1074 -VHVWLVDSGIVLH-SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSV 1131
+ V LV ++ H G S+ + + + V++ G N +++ A G E N +
Sbjct: 79 ALLVSLVCRSVLHHFHFKGSVHSVSFSPDGRKFVVTKG-NIAQMYH-APGKKREFNAFVL 136
Query: 1132 SHA-----ERITCFALTADSQHVVTGSMDMSLKVWKLD--GGKLSQVLVGHSD-IVTCVA 1183
+ TC T DS+ V GS DMS V+ + + L GH D IV C
Sbjct: 137 DKTYFGPYDETTCIDWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKDAIVACFF 196
Query: 1184 VSITNKTQVVSGSWDCNLIVWDINT 1208
S N + S S D L +W +T
Sbjct: 197 ES--NSLDLYSLSQDGVLCMWQCDT 219
>U86136-1|AAC51107.1| 2627|Homo sapiens telomerase-associated protein
TP-1 protein.
Length = 2627
Score = 63.7 bits (148), Expect = 5e-09
Identities = 62/271 (22%), Positives = 114/271 (42%), Gaps = 12/271 (4%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL-ADNSPSLTYK---GHSSAIQTLLMM 1059
L GH G ++C +FS + + +G DR+++ W + +P L + H +
Sbjct: 2057 LRGHEGPVSCCSFSTDGGSLATGGRDRSLLCWDVRTPKTPVLIHSFPACHRDWVTGCAWT 2116
Query: 1060 SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLS-DGDNSVRIWSL 1118
D +S +V +W +SG L G +++ ++ V+S D ++++W
Sbjct: 2117 KD-NLLISCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVAAVEEHVVSVSRDGTLKVWDH 2175
Query: 1119 AGGDNSEDNRRS--VSH---AERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLV 1173
G + + S +SH A VVT +D + ++W + L+
Sbjct: 2176 QGVELTSIPAHSGPISHCAAAMEPRAAGQPGSELLVVTVGLDGATRLWHPLLVCQTHTLL 2235
Query: 1174 GHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTI 1233
GHS V AVS T+ +++ S D ++ +W + VT V DG++
Sbjct: 2236 GHSGPVRAAAVSETSGL-MLTASEDGSVRLWQVPKEADDTCIPRSSAAVTAVAWAPDGSM 2294
Query: 1234 AVSCAEDKTLIIWETKRGLALTSFSLHVPLL 1264
AVS + LI+W+ + +A H+ L
Sbjct: 2295 AVSGNQAGELILWQEAKAVATAQAPGHIGAL 2325
Score = 60.5 bits (140), Expect = 4e-08
Identities = 44/176 (25%), Positives = 75/176 (42%), Gaps = 7/176 (3%)
Query: 662 PSGQHLVLAPSA-GDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
P + LV+ G +LWH + + HT GHSG + V+ S +LT SED SV +
Sbjct: 2205 PGSELLVVTVGLDGATRLWHPLLVCQTHTLLGHSGPVRAAAVSETSGLMLTASEDGSVRL 2264
Query: 721 WDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
W + A T I A V VA + S+ +SG +I+ + H G+
Sbjct: 2265 WQVPKEADDTCIPRSSAAVTAVAWAPDGSMAVSGNQAGELILWQEAKAVATAQAPGHIGA 2324
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
+ + + F S D + W V+ + + +H+ + +++ +LT
Sbjct: 2325 L----IWSSAHTFFVLSADEKISEWQVK--LRKGSAPGNLSLHLNRILQEDLGVLT 2374
Score = 52.8 bits (121), Expect = 9e-06
Identities = 36/137 (26%), Positives = 64/137 (46%), Gaps = 9/137 (6%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPV-----LCVAAI 745
+GH G + C + + L TG D S++ WD+ T KT +L H P + A
Sbjct: 2058 RGHEGPVSCCSFSTDGGSLATGGRDRSLLCWDVRT--PKTPVLIHSFPACHRDWVTGCAW 2115
Query: 746 VNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
+L+IS D +V + G + + H+ +V++V +++ + + S+DGT+ W
Sbjct: 2116 TKDNLLISCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVAAVEEHVVSV--SRDGTLKVW 2173
Query: 806 NVENFTLLSTVTAGVPI 822
+ + L S PI
Sbjct: 2174 DHQGVELTSIPAHSGPI 2190
Score = 52.0 bits (119), Expect = 2e-05
Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 20/154 (12%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
L+ S G LW S ++ F GH ++ + E ++++ S D ++ VWD H
Sbjct: 2121 LISCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVAAVEE--HVVSVSRDGTLKVWD-HQG 2177
Query: 727 AVKTKILEHIAPVL-CVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH--------- 776
T I H P+ C AA+ R+ G + +++T +DGA T+L H
Sbjct: 2178 VELTSIPAHSGPISHCAAAMEPRAAGQPGSE--LLVVTVGLDGA--TRLWHPLLVCQTHT 2233
Query: 777 ---HRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
H G V + V + + +T S+DG+V W V
Sbjct: 2234 LLGHSGPVRAAAVSETSGLMLTASEDGSVRLWQV 2267
Score = 50.0 bits (114), Expect = 6e-05
Identities = 37/150 (24%), Positives = 62/150 (41%), Gaps = 2/150 (1%)
Query: 988 GLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYK 1047
G R+W TL GH G + S + L+L+ SED +V +WQ+ +
Sbjct: 2218 GATRLWHPLLVCQTHTLLGHSGPVRAAAVSETSGLMLTASEDGSVRLWQVPKEADDTCIP 2277
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLS 1107
S+A+ + DG A+S ++A + +W + A G ++ + + VLS
Sbjct: 2278 RSSAAVTAVAWAPDGSMAVSGNQAGELILWQEAKAVATAQAPGHIGALIWSSAHTFFVLS 2337
Query: 1108 DGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
D + W + S S+ H RI
Sbjct: 2338 -ADEKISEWQVKLRKGSAPGNLSL-HLNRI 2365
Score = 47.2 bits (107), Expect = 4e-04
Identities = 71/312 (22%), Positives = 128/312 (41%), Gaps = 30/312 (9%)
Query: 968 PISCLEVSRD-GQLGASGCARGLVRVWQLSTHRLQATLNG----HIGHITCVTFSPNNLL 1022
P+SC S D G L G R L+ W + T + ++ H +T ++ +NLL
Sbjct: 2063 PVSCCSFSTDGGSLATGGRDRSLL-CWDVRTPKTPVLIHSFPACHRDWVTGCAWTKDNLL 2121
Query: 1023 VLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNV--HVWLVD 1080
+ S S D +V +W + GH SA+ + + + ++S D V H +
Sbjct: 2122 I-SCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVAAVEEHVVSVSRDGTLKVWDHQGVEL 2180
Query: 1081 SGIVLHSATGPSASIDVTLNMKYA--------VLSDG-DNSVRIWSLAGGDNSEDNRRSV 1131
+ I HS GP + + + A V++ G D + R+W +
Sbjct: 2181 TSIPAHS--GPISHCAAAMEPRAAGQPGSELLVVTVGLDGATRLWHPL---LVCQTHTLL 2235
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQ 1191
H+ + A++ S ++T S D S+++W++ + S VT VA + + +
Sbjct: 2236 GHSGPVRAAAVSETSGLMLTASEDGSVRLWQVPKEADDTCIPRSSAAVTAVAWA-PDGSM 2294
Query: 1192 VVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK-- 1249
VSG+ LI+W + + + T V A++K + W+ K
Sbjct: 2295 AVSGNQAGELILWQ---EAKAVATAQAPGHIGALIWSSAHTFFVLSADEK-ISEWQVKLR 2350
Query: 1250 RGLALTSFSLHV 1261
+G A + SLH+
Sbjct: 2351 KGSAPGNLSLHL 2362
Score = 42.7 bits (96), Expect = 0.009
Identities = 63/295 (21%), Positives = 113/295 (38%), Gaps = 20/295 (6%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
++C+ +GQ+ A+G G + +Q+ ++ L I + F+ +V G
Sbjct: 1803 LNCVAFHPEGQVIATGSWAGSISFFQVDGLKVTKDLGAPGASIRTLAFNVPGGVVAVGRL 1862
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D V +W + + + H + L + G + +++ V VW SG L
Sbjct: 1863 DSMVELWAWREGARLAAFPAHHGFVAAALFLHAGCQLLTAGEDGKVQVW---SG-SLGRP 1918
Query: 1089 TGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDN----SEDNRRSVSHAERITCFALTA 1144
G S+ ++ + A+ DGD V + A G S ++ + A + AL
Sbjct: 1919 RGHLGSLSLSPALSVALSPDGDR-VAVGYRADGIRIYKISSGSQGAQGQALDVAVSALAW 1977
Query: 1145 DSQHV-VTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIV 1203
S V V+G+ D SL+ W L L Q L S V T++ + S S D + +
Sbjct: 1978 LSPKVLVSGAEDGSLQGWALKECSL-QSLWLLSRFQKPVLGLATSQELLASASEDFTVQL 2036
Query: 1204 WDINTXXX---------XXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
W V+C + DG + D++L+ W+ +
Sbjct: 2037 WPRQLLTRPHKAEDFPCGTELRGHEGPVSCCSFSTDGGSLATGGRDRSLLCWDVR 2091
Score = 40.7 bits (91), Expect = 0.038
Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 5/149 (3%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKV--HTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L+P + L G +LW + HT+ S+ C+ E Q + TGS S
Sbjct: 1767 LSPDCRLLATVCLGGCLKLWDTVRGQLAFQHTYPK---SLNCVAFHPEGQVIATGSWAGS 1823
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ + + L V + A + +A V +V G DS V + + +GA + H
Sbjct: 1824 ISFFQVDGLKVTKDLGAPGASIRTLAFNVPGGVVAVGRLDSMVELWAWREGARLAAFPAH 1883
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
G V + + G +T +DG V W+
Sbjct: 1884 HGFVAAALFLHAGCQLLTAGEDGKVQVWS 1912
Score = 35.1 bits (77), Expect = 1.9
Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 8/135 (5%)
Query: 172 LIYGPDASGKTTLLTHLYTKCEEIFSKPVLRII--RFSASTPRSAYNLELLRVMCQQISI 229
L+ G GKT L L + + V ++ FS + P L LLR +C +
Sbjct: 1165 LVTGQSGQGKTAFLASLVSALQAPDGAKVAPLVFFHFSGARPDQGLALTLLRRLCTYLRG 1224
Query: 230 ILNIPEGYLPKDASFDPLYINNWFQSLLRRCEEME-NEILFIFIDNVHRVNPLECDIVTG 288
L P G LP +++ L + L + E + + + ID R+ +++
Sbjct: 1225 QLKEP-GALP--STYRSLVWELQQRLLPKSAESLHPGQTQVLIIDGADRLVDQNGQLIS- 1280
Query: 289 LSWLPMSLPRNVFLV 303
W+P LPR V LV
Sbjct: 1281 -DWIPKKLPRCVHLV 1294
Score = 34.7 bits (76), Expect = 2.5
Identities = 41/163 (25%), Positives = 72/163 (44%), Gaps = 22/163 (13%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTR----ESQYLLTGSED 715
L+P G + + A +++ I S S+ G G L + V+ + L++G+ED
Sbjct: 1935 LSPDGDRVAVGYRADGIRIYKISSGSQ-----GAQGQALDVAVSALAWLSPKVLVSGAED 1989
Query: 716 TSVIVWDLHTLAVKTKIL--EHIAPVLCVAAIVNRSLVISGGDDSAV------IIT---S 764
S+ W L ++++ L PVL +A ++ L+ S +D V ++T
Sbjct: 1990 GSLQGWALKECSLQSLWLLSRFQKPVLGLAT--SQELLASASEDFTVQLWPRQLLTRPHK 2047
Query: 765 LVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
D T+L H G V+ DG TG +D ++ W+V
Sbjct: 2048 AEDFPCGTELRGHEGPVSCCSFSTDGGSLATGGRDRSLLCWDV 2090
Score = 33.5 bits (73), Expect = 5.7
Identities = 34/188 (18%), Positives = 72/188 (38%), Gaps = 8/188 (4%)
Query: 1073 NVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVS 1132
++ W + +V G SA + ++ + + DG + +W L G + +
Sbjct: 1704 DLRTWQEEKSVV-SGCDGISACLFLSDDTLFLTAFDG--LLELWDLQHGCRVLQTK---A 1757
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H +IT L+ D + + T + LK+W G+L+ + + CVA + +
Sbjct: 1758 HQYQITGCCLSPDCRLLATVCLGGCLKLWDTVRGQLA-FQHTYPKSLNCVAFHPEGQV-I 1815
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
+GSW ++ + ++ + + G + D + +W + G
Sbjct: 1816 ATGSWAGSISFFQVDGLKVTKDLGAPGASIRTLAFNVPGGVVAVGRLDSMVELWAWREGA 1875
Query: 1253 ALTSFSLH 1260
L +F H
Sbjct: 1876 RLAAFPAH 1883
>U56089-1|AAC50905.1| 919|Homo sapiens periodic tryptophan protein 2
protein.
Length = 919
Score = 63.7 bits (148), Expect = 5e-09
Identities = 65/317 (20%), Positives = 122/317 (38%), Gaps = 8/317 (2%)
Query: 941 PTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRL 1000
P ++ K + K + ++ D ++ + L +G A G+ + +L L
Sbjct: 263 PAEEEKTGKVKYSRLAKYFFNKEGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNL 322
Query: 1001 QATLNGHIGHITCVTFSPNNLLVLSGSEDR-TVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
+L+ I V + + + G ++VW+ S L +GH +++ L
Sbjct: 323 IHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYS 382
Query: 1060 SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMK-YAVL-SDGDNSVRIW 1116
DG+ ++ V VW SG + T S+ + VT Y V+ S D +VR +
Sbjct: 383 PDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 1117 SLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD-MSLKVWKLDGGKLSQVLVGH 1175
L N + + +C A+ A + V G+ D + VW + G+L VL GH
Sbjct: 443 DLHRYRNF--RTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGH 500
Query: 1176 SDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAV 1235
++ + + K+ + S SWD + +WD+ V DG
Sbjct: 501 EGPISGLCFN-PMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRPDGAELA 559
Query: 1236 SCAEDKTLIIWETKRGL 1252
+ + W+ + +
Sbjct: 560 VATLNSQITFWDPENAV 576
Score = 61.3 bits (142), Expect = 2e-08
Identities = 47/228 (20%), Positives = 90/228 (39%), Gaps = 4/228 (1%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS-VIVWDLHT 725
LV ++G L + + +H+ SI + + ++ G ++VW+ +
Sbjct: 303 LVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQS 362
Query: 726 LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVK 785
+ K H ++ +A + +++GGDD V + + + G H VT V
Sbjct: 363 ESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVT 422
Query: 786 VIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDD---NVFLLTLQGDNE 842
G + +T S DGTV +++ + T T+ P V D + Q E
Sbjct: 423 FTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFE 482
Query: 843 LHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ + + TG L L H+ + C S +A D+ + L+ +
Sbjct: 483 IFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 60.1 bits (139), Expect = 6e-08
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 2/152 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L +P GQ++V G ++W+ +S TF HS + + T ++T S D +
Sbjct: 379 LAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGT 438
Query: 718 VIVWDLHTLA-VKTKILEHIAPVLCVAAIVNRSLVISGGDDS-AVIITSLVDGALVTKLD 775
V +DLH +T CVA + +V +G DS + + S+ G L+ L
Sbjct: 439 VRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLS 498
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
H G ++ + ++ + S D TV W++
Sbjct: 499 GHEGPISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 48.8 bits (111), Expect = 1e-04
Identities = 35/130 (26%), Positives = 53/130 (40%), Gaps = 3/130 (2%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H + A + D Q++VTG D +KVW G HS VT V + T V
Sbjct: 372 HFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYV-V 430
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXX-XXXKVTCVKVTGDGTIAVSCAEDK-TLIIWETKR 1250
V+ S D + +D++ + +CV V G I + A+D + +W +
Sbjct: 431 VTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQT 490
Query: 1251 GLALTSFSLH 1260
G L S H
Sbjct: 491 GRLLDVLSGH 500
Score = 48.4 bits (110), Expect = 2e-04
Identities = 46/224 (20%), Positives = 89/224 (39%), Gaps = 8/224 (3%)
Query: 962 EQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNL 1021
+Q + L S DGQ +G G V+VW + T H +T VTF+
Sbjct: 369 QQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGY 428
Query: 1022 LVLSGSEDRTVVVWQLADNSPSLTYKG-HSSAIQTLLMMSDGR-RAMSSDRARNVHVWLV 1079
+V++ S D TV + L T+ + + + + G + + + + VW +
Sbjct: 429 VVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSM 488
Query: 1080 DSGIVLHSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAER 1136
+G +L +G I + N +VL+ D +VR+W + +++ S A
Sbjct: 489 QTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALA 548
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVT 1180
+T D + +++ + W + + + G D+ T
Sbjct: 549 VT---FRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKT 589
Score = 42.3 bits (95), Expect = 0.012
Identities = 41/168 (24%), Positives = 70/168 (41%), Gaps = 12/168 (7%)
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
+Y V D V++W+ G H+ +T TA VVT SMD +++ +
Sbjct: 386 QYIVTGGDDGKVKVWNTLSGFCFVT---FTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 1162 KLDGGKLSQVLVGHSDI-VTCVAVSITNKTQVVSGSWDC-NLIVWDINTXXXXXXXXXXX 1219
L + + +CVAV + + V +G+ D + VW + T
Sbjct: 443 DLHRYRNFRTFTSPRPTQFSCVAVDASGEI-VSAGAQDSFEIFVWSMQTGRLLDVLSGHE 501
Query: 1220 XKVTCVKVTGDGTIAVSCAEDKTLIIWE------TKRGLALTSFSLHV 1261
++ + ++ S + DKT+ +W+ TK LALTS +L V
Sbjct: 502 GPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAV 549
Score = 33.9 bits (74), Expect = 4.3
Identities = 54/205 (26%), Positives = 87/205 (42%), Gaps = 15/205 (7%)
Query: 1014 VTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARN 1073
+ F+ N V+S +R V V+ L +N ++ + + DGR A+ D +
Sbjct: 20 LNFTCNGNSVISPVGNR-VTVFDLKNNKSDTLPLATRYNVKCVGLSPDGRLAIIVDEGGD 78
Query: 1074 -VHVWLVDSGIVLH-SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSV 1131
+ V LV ++ H G S+ + + + V++ G N +++ A G E N +
Sbjct: 79 ALLVSLVCRSVLHHFHFKGSVHSVSFSPDGRKFVVTKG-NIAQMYH-APGKKREFNAFVL 136
Query: 1132 SHA-----ERITCFALTADSQHVVTGSMDMSLKVWKLD--GGKLSQVLVGHSD-IVTCVA 1183
+ TC T DS+ V GS DMS V+ + + L GH D IV C
Sbjct: 137 DKTYFGPYDETTCIDWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKDAIVACFF 196
Query: 1184 VSITNKTQVVSGSWDCNLIVWDINT 1208
S N + S S D L +W +T
Sbjct: 197 ES--NSLDLYSLSQDGVLCMWQCDT 219
>U56085-1|AAC50904.1| 919|Homo sapiens periodic tryptophan protein 2
protein.
Length = 919
Score = 63.7 bits (148), Expect = 5e-09
Identities = 65/317 (20%), Positives = 122/317 (38%), Gaps = 8/317 (2%)
Query: 941 PTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRL 1000
P ++ K + K + ++ D ++ + L +G A G+ + +L L
Sbjct: 263 PAEEEKTGKVKYSRLAKYFFNKEGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNL 322
Query: 1001 QATLNGHIGHITCVTFSPNNLLVLSGSEDR-TVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
+L+ I V + + + G ++VW+ S L +GH +++ L
Sbjct: 323 IHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYS 382
Query: 1060 SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMK-YAVL-SDGDNSVRIW 1116
DG+ ++ V VW SG + T S+ + VT Y V+ S D +VR +
Sbjct: 383 PDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 1117 SLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD-MSLKVWKLDGGKLSQVLVGH 1175
L N + + +C A+ A + V G+ D + VW + G+L VL GH
Sbjct: 443 DLHRYRNF--RTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGH 500
Query: 1176 SDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAV 1235
++ + + K+ + S SWD + +WD+ V DG
Sbjct: 501 EGPISGLCFN-PMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRPDGAELA 559
Query: 1236 SCAEDKTLIIWETKRGL 1252
+ + W+ + +
Sbjct: 560 VATLNSQITFWDPENAV 576
Score = 61.3 bits (142), Expect = 2e-08
Identities = 47/228 (20%), Positives = 90/228 (39%), Gaps = 4/228 (1%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS-VIVWDLHT 725
LV ++G L + + +H+ SI + + ++ G ++VW+ +
Sbjct: 303 LVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQS 362
Query: 726 LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVK 785
+ K H ++ +A + +++GGDD V + + + G H VT V
Sbjct: 363 ESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVT 422
Query: 786 VIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDD---NVFLLTLQGDNE 842
G + +T S DGTV +++ + T T+ P V D + Q E
Sbjct: 423 FTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFE 482
Query: 843 LHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ + + TG L L H+ + C S +A D+ + L+ +
Sbjct: 483 IFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 60.1 bits (139), Expect = 6e-08
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 2/152 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L +P GQ++V G ++W+ +S TF HS + + T ++T S D +
Sbjct: 379 LAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGT 438
Query: 718 VIVWDLHTLA-VKTKILEHIAPVLCVAAIVNRSLVISGGDDS-AVIITSLVDGALVTKLD 775
V +DLH +T CVA + +V +G DS + + S+ G L+ L
Sbjct: 439 VRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLS 498
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
H G ++ + ++ + S D TV W++
Sbjct: 499 GHEGPISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 48.8 bits (111), Expect = 1e-04
Identities = 35/130 (26%), Positives = 53/130 (40%), Gaps = 3/130 (2%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H + A + D Q++VTG D +KVW G HS VT V + T V
Sbjct: 372 HFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYV-V 430
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXX-XXXKVTCVKVTGDGTIAVSCAEDK-TLIIWETKR 1250
V+ S D + +D++ + +CV V G I + A+D + +W +
Sbjct: 431 VTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQT 490
Query: 1251 GLALTSFSLH 1260
G L S H
Sbjct: 491 GRLLDVLSGH 500
Score = 48.4 bits (110), Expect = 2e-04
Identities = 46/224 (20%), Positives = 89/224 (39%), Gaps = 8/224 (3%)
Query: 962 EQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNL 1021
+Q + L S DGQ +G G V+VW + T H +T VTF+
Sbjct: 369 QQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGY 428
Query: 1022 LVLSGSEDRTVVVWQLADNSPSLTYKG-HSSAIQTLLMMSDGR-RAMSSDRARNVHVWLV 1079
+V++ S D TV + L T+ + + + + G + + + + VW +
Sbjct: 429 VVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSM 488
Query: 1080 DSGIVLHSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAER 1136
+G +L +G I + N +VL+ D +VR+W + +++ S A
Sbjct: 489 QTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALA 548
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVT 1180
+T D + +++ + W + + + G D+ T
Sbjct: 549 VT---FRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKT 589
Score = 42.3 bits (95), Expect = 0.012
Identities = 41/168 (24%), Positives = 70/168 (41%), Gaps = 12/168 (7%)
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
+Y V D V++W+ G H+ +T TA VVT SMD +++ +
Sbjct: 386 QYIVTGGDDGKVKVWNTLSGFCFVT---FTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 1162 KLDGGKLSQVLVGHSDI-VTCVAVSITNKTQVVSGSWDC-NLIVWDINTXXXXXXXXXXX 1219
L + + +CVAV + + V +G+ D + VW + T
Sbjct: 443 DLHRYRNFRTFTSPRPTQFSCVAVDASGEI-VSAGAQDSFEIFVWSMQTGRLLDVLSGHE 501
Query: 1220 XKVTCVKVTGDGTIAVSCAEDKTLIIWE------TKRGLALTSFSLHV 1261
++ + ++ S + DKT+ +W+ TK LALTS +L V
Sbjct: 502 GPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAV 549
Score = 33.9 bits (74), Expect = 4.3
Identities = 54/205 (26%), Positives = 87/205 (42%), Gaps = 15/205 (7%)
Query: 1014 VTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARN 1073
+ F+ N V+S +R V V+ L +N ++ + + DGR A+ D +
Sbjct: 20 LNFTCNGNSVISPVGNR-VTVFDLKNNKSDTLPLATRYNVKCVGLSPDGRLAIIVDEGGD 78
Query: 1074 -VHVWLVDSGIVLH-SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSV 1131
+ V LV ++ H G S+ + + + V++ G N +++ A G E N +
Sbjct: 79 ALLVSLVCRSVLHHFHFKGSVHSVSFSPDGRKFVVTKG-NIAQMYH-APGKKREFNAFVL 136
Query: 1132 SHA-----ERITCFALTADSQHVVTGSMDMSLKVWKLD--GGKLSQVLVGHSD-IVTCVA 1183
+ TC T DS+ V GS DMS V+ + + L GH D IV C
Sbjct: 137 DKTYFGPYDETTCIDWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKDAIVACFF 196
Query: 1184 VSITNKTQVVSGSWDCNLIVWDINT 1208
S N + S S D L +W +T
Sbjct: 197 ES--NSLDLYSLSQDGVLCMWQCDT 219
>U53346-1|AAB08084.1| 919|Homo sapiens PWP2H protein protein.
Length = 919
Score = 63.7 bits (148), Expect = 5e-09
Identities = 65/317 (20%), Positives = 122/317 (38%), Gaps = 8/317 (2%)
Query: 941 PTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRL 1000
P ++ K + K + ++ D ++ + L +G A G+ + +L L
Sbjct: 263 PAEEEKTGKVKYSRLAKYFFNKEGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNL 322
Query: 1001 QATLNGHIGHITCVTFSPNNLLVLSGSEDR-TVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
+L+ I V + + + G ++VW+ S L +GH +++ L
Sbjct: 323 IHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYS 382
Query: 1060 SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMK-YAVL-SDGDNSVRIW 1116
DG+ ++ V VW SG + T S+ + VT Y V+ S D +VR +
Sbjct: 383 PDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 1117 SLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD-MSLKVWKLDGGKLSQVLVGH 1175
L N + + +C A+ A + V G+ D + VW + G+L VL GH
Sbjct: 443 DLHRYRNF--RTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGH 500
Query: 1176 SDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAV 1235
++ + + K+ + S SWD + +WD+ V DG
Sbjct: 501 EGPISGLCFN-PMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRPDGAELA 559
Query: 1236 SCAEDKTLIIWETKRGL 1252
+ + W+ + +
Sbjct: 560 VATLNSQITFWDPENAV 576
Score = 61.3 bits (142), Expect = 2e-08
Identities = 47/228 (20%), Positives = 90/228 (39%), Gaps = 4/228 (1%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS-VIVWDLHT 725
LV ++G L + + +H+ SI + + ++ G ++VW+ +
Sbjct: 303 LVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQS 362
Query: 726 LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVK 785
+ K H ++ +A + +++GGDD V + + + G H VT V
Sbjct: 363 ESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVT 422
Query: 786 VIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDD---NVFLLTLQGDNE 842
G + +T S DGTV +++ + T T+ P V D + Q E
Sbjct: 423 FTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFE 482
Query: 843 LHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ + + TG L L H+ + C S +A D+ + L+ +
Sbjct: 483 IFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 60.1 bits (139), Expect = 6e-08
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 2/152 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L +P GQ++V G ++W+ +S TF HS + + T ++T S D +
Sbjct: 379 LAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGT 438
Query: 718 VIVWDLHTLA-VKTKILEHIAPVLCVAAIVNRSLVISGGDDS-AVIITSLVDGALVTKLD 775
V +DLH +T CVA + +V +G DS + + S+ G L+ L
Sbjct: 439 VRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLS 498
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
H G ++ + ++ + S D TV W++
Sbjct: 499 GHEGPISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 48.8 bits (111), Expect = 1e-04
Identities = 35/130 (26%), Positives = 53/130 (40%), Gaps = 3/130 (2%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H + A + D Q++VTG D +KVW G HS VT V + T V
Sbjct: 372 HFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYV-V 430
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXX-XXXKVTCVKVTGDGTIAVSCAEDK-TLIIWETKR 1250
V+ S D + +D++ + +CV V G I + A+D + +W +
Sbjct: 431 VTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQT 490
Query: 1251 GLALTSFSLH 1260
G L S H
Sbjct: 491 GRLLDVLSGH 500
Score = 48.4 bits (110), Expect = 2e-04
Identities = 46/224 (20%), Positives = 89/224 (39%), Gaps = 8/224 (3%)
Query: 962 EQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNL 1021
+Q + L S DGQ +G G V+VW + T H +T VTF+
Sbjct: 369 QQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGY 428
Query: 1022 LVLSGSEDRTVVVWQLADNSPSLTYKG-HSSAIQTLLMMSDGR-RAMSSDRARNVHVWLV 1079
+V++ S D TV + L T+ + + + + G + + + + VW +
Sbjct: 429 VVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSM 488
Query: 1080 DSGIVLHSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAER 1136
+G +L +G I + N +VL+ D +VR+W + +++ S A
Sbjct: 489 QTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALA 548
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVT 1180
+T D + +++ + W + + + G D+ T
Sbjct: 549 VT---FRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKT 589
Score = 42.3 bits (95), Expect = 0.012
Identities = 41/168 (24%), Positives = 70/168 (41%), Gaps = 12/168 (7%)
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
+Y V D V++W+ G H+ +T TA VVT SMD +++ +
Sbjct: 386 QYIVTGGDDGKVKVWNTLSGFCFVT---FTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 1162 KLDGGKLSQVLVGHSDI-VTCVAVSITNKTQVVSGSWDC-NLIVWDINTXXXXXXXXXXX 1219
L + + +CVAV + + V +G+ D + VW + T
Sbjct: 443 DLHRYRNFRTFTSPRPTQFSCVAVDASGEI-VSAGAQDSFEIFVWSMQTGRLLDVLSGHE 501
Query: 1220 XKVTCVKVTGDGTIAVSCAEDKTLIIWE------TKRGLALTSFSLHV 1261
++ + ++ S + DKT+ +W+ TK LALTS +L V
Sbjct: 502 GPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAV 549
Score = 33.9 bits (74), Expect = 4.3
Identities = 54/205 (26%), Positives = 87/205 (42%), Gaps = 15/205 (7%)
Query: 1014 VTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARN 1073
+ F+ N V+S +R V V+ L +N ++ + + DGR A+ D +
Sbjct: 20 LNFTCNGNSVISPVGNR-VTVFDLKNNKSDTLPLATRYNVKCVGLSPDGRLAIIVDEGGD 78
Query: 1074 -VHVWLVDSGIVLH-SATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSV 1131
+ V LV ++ H G S+ + + + V++ G N +++ A G E N +
Sbjct: 79 ALLVSLVCRSVLHHFHFKGSVHSVSFSPDGRKFVVTKG-NIAQMYH-APGKKREFNAFVL 136
Query: 1132 SHA-----ERITCFALTADSQHVVTGSMDMSLKVWKLD--GGKLSQVLVGHSD-IVTCVA 1183
+ TC T DS+ V GS DMS V+ + + L GH D IV C
Sbjct: 137 DKTYFGPYDETTCIDWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKDAIVACFF 196
Query: 1184 VSITNKTQVVSGSWDCNLIVWDINT 1208
S N + S S D L +W +T
Sbjct: 197 ES--NSLDLYSLSQDGVLCMWQCDT 219
>BC126107-1|AAI26108.1| 2627|Homo sapiens telomerase-associated
protein 1 protein.
Length = 2627
Score = 63.7 bits (148), Expect = 5e-09
Identities = 62/271 (22%), Positives = 114/271 (42%), Gaps = 12/271 (4%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL-ADNSPSLTYK---GHSSAIQTLLMM 1059
L GH G ++C +FS + + +G DR+++ W + +P L + H +
Sbjct: 2057 LRGHEGPVSCCSFSTDGGSLATGGRDRSLLCWDVRTPKTPVLIHSFPACHRDWVTGCAWT 2116
Query: 1060 SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLS-DGDNSVRIWSL 1118
D +S +V +W +SG L G +++ ++ V+S D ++++W
Sbjct: 2117 KD-NLLISCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVAAVEEHVVSVSRDGTLKVWDH 2175
Query: 1119 AGGDNSEDNRRS--VSH---AERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLV 1173
G + + S +SH A VVT +D + ++W + L+
Sbjct: 2176 QGVELTSIPAHSGPISHCAAAMEPRAAGQPGSELLVVTVGLDGATRLWHPLLVCQTHTLL 2235
Query: 1174 GHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTI 1233
GHS V AVS T+ +++ S D ++ +W + VT V DG++
Sbjct: 2236 GHSGPVRAAAVSETSGL-MLTASEDGSVRLWQVPKEADDTCIPRSSAAVTAVAWAPDGSM 2294
Query: 1234 AVSCAEDKTLIIWETKRGLALTSFSLHVPLL 1264
AVS + LI+W+ + +A H+ L
Sbjct: 2295 AVSGNQAGELILWQEAKAVATAQAPGHIGAL 2325
Score = 60.5 bits (140), Expect = 4e-08
Identities = 44/176 (25%), Positives = 75/176 (42%), Gaps = 7/176 (3%)
Query: 662 PSGQHLVLAPSA-GDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
P + LV+ G +LWH + + HT GHSG + V+ S +LT SED SV +
Sbjct: 2205 PGSELLVVTVGLDGATRLWHPLLVCQTHTLLGHSGPVRAAAVSETSGLMLTASEDGSVRL 2264
Query: 721 WDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
W + A T I A V VA + S+ +SG +I+ + H G+
Sbjct: 2265 WQVPKEADDTCIPRSSAAVTAVAWAPDGSMAVSGNQAGELILWQEAKAVATAQAPGHIGA 2324
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
+ + + F S D + W V+ + + +H+ + +++ +LT
Sbjct: 2325 L----IWSSAHTFFVLSADEKISEWQVK--LRKGSAPGNLSLHLNRILQEDLGVLT 2374
Score = 52.8 bits (121), Expect = 9e-06
Identities = 36/137 (26%), Positives = 64/137 (46%), Gaps = 9/137 (6%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPV-----LCVAAI 745
+GH G + C + + L TG D S++ WD+ T KT +L H P + A
Sbjct: 2058 RGHEGPVSCCSFSTDGGSLATGGRDRSLLCWDVRT--PKTPVLIHSFPACHRDWVTGCAW 2115
Query: 746 VNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
+L+IS D +V + G + + H+ +V++V +++ + + S+DGT+ W
Sbjct: 2116 TKDNLLISCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVAAVEEHVVSV--SRDGTLKVW 2173
Query: 806 NVENFTLLSTVTAGVPI 822
+ + L S PI
Sbjct: 2174 DHQGVELTSIPAHSGPI 2190
Score = 52.0 bits (119), Expect = 2e-05
Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 20/154 (12%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
L+ S G LW S ++ F GH ++ + E ++++ S D ++ VWD H
Sbjct: 2121 LISCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVAAVEE--HVVSVSRDGTLKVWD-HQG 2177
Query: 727 AVKTKILEHIAPVL-CVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH--------- 776
T I H P+ C AA+ R+ G + +++T +DGA T+L H
Sbjct: 2178 VELTSIPAHSGPISHCAAAMEPRAAGQPGSE--LLVVTVGLDGA--TRLWHPLLVCQTHT 2233
Query: 777 ---HRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
H G V + V + + +T S+DG+V W V
Sbjct: 2234 LLGHSGPVRAAAVSETSGLMLTASEDGSVRLWQV 2267
Score = 50.0 bits (114), Expect = 6e-05
Identities = 37/150 (24%), Positives = 62/150 (41%), Gaps = 2/150 (1%)
Query: 988 GLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYK 1047
G R+W TL GH G + S + L+L+ SED +V +WQ+ +
Sbjct: 2218 GATRLWHPLLVCQTHTLLGHSGPVRAAAVSETSGLMLTASEDGSVRLWQVPKEADDTCIP 2277
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLS 1107
S+A+ + DG A+S ++A + +W + A G ++ + + VLS
Sbjct: 2278 RSSAAVTAVAWAPDGSMAVSGNQAGELILWQEAKAVATAQAPGHIGALIWSSAHTFFVLS 2337
Query: 1108 DGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
D + W + S S+ H RI
Sbjct: 2338 -ADEKISEWQVKLRKGSAPGNLSL-HLNRI 2365
Score = 47.2 bits (107), Expect = 4e-04
Identities = 71/312 (22%), Positives = 128/312 (41%), Gaps = 30/312 (9%)
Query: 968 PISCLEVSRD-GQLGASGCARGLVRVWQLSTHRLQATLNG----HIGHITCVTFSPNNLL 1022
P+SC S D G L G R L+ W + T + ++ H +T ++ +NLL
Sbjct: 2063 PVSCCSFSTDGGSLATGGRDRSLL-CWDVRTPKTPVLIHSFPACHRDWVTGCAWTKDNLL 2121
Query: 1023 VLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNV--HVWLVD 1080
+ S S D +V +W + GH SA+ + + + ++S D V H +
Sbjct: 2122 I-SCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVAAVEEHVVSVSRDGTLKVWDHQGVEL 2180
Query: 1081 SGIVLHSATGPSASIDVTLNMKYA--------VLSDG-DNSVRIWSLAGGDNSEDNRRSV 1131
+ I HS GP + + + A V++ G D + R+W +
Sbjct: 2181 TSIPAHS--GPISHCAAAMEPRAAGQPGSELLVVTVGLDGATRLWHPL---LVCQTHTLL 2235
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQ 1191
H+ + A++ S ++T S D S+++W++ + S VT VA + + +
Sbjct: 2236 GHSGPVRAAAVSETSGLMLTASEDGSVRLWQVPKEADDTCIPRSSAAVTAVAWA-PDGSM 2294
Query: 1192 VVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK-- 1249
VSG+ LI+W + + + T V A++K + W+ K
Sbjct: 2295 AVSGNQAGELILWQ---EAKAVATAQAPGHIGALIWSSAHTFFVLSADEK-ISEWQVKLR 2350
Query: 1250 RGLALTSFSLHV 1261
+G A + SLH+
Sbjct: 2351 KGSAPGNLSLHL 2362
Score = 42.7 bits (96), Expect = 0.009
Identities = 63/295 (21%), Positives = 113/295 (38%), Gaps = 20/295 (6%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
++C+ +GQ+ A+G G + +Q+ ++ L I + F+ +V G
Sbjct: 1803 LNCVAFHPEGQVIATGSWAGSISFFQVDGLKVTKDLGAPGASIRTLAFNVPGGVVAVGRL 1862
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D V +W + + + H + L + G + +++ V VW SG L
Sbjct: 1863 DSMVELWAWREGARLAAFPAHHGFVAAALFLHAGCQLLTAGEDGKVQVW---SG-SLGRP 1918
Query: 1089 TGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDN----SEDNRRSVSHAERITCFALTA 1144
G S+ ++ + A+ DGD V + A G S ++ + A + AL
Sbjct: 1919 RGHLGSLSLSPALSVALSPDGDR-VAVGYRADGIRIYKISSGSQGAQGQALDVAVSALAW 1977
Query: 1145 DSQHV-VTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIV 1203
S V V+G+ D SL+ W L L Q L S V T++ + S S D + +
Sbjct: 1978 LSPKVLVSGAEDGSLQGWALKECSL-QSLWLLSRFQKPVLGLATSQELLASASEDFTVQL 2036
Query: 1204 WDINTXXX---------XXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
W V+C + DG + D++L+ W+ +
Sbjct: 2037 WPRQLLTRPHKAEDFPCGTELRGHEGPVSCCSFSTDGGSLATGGRDRSLLCWDVR 2091
Score = 40.7 bits (91), Expect = 0.038
Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 5/149 (3%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKV--HTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L+P + L G +LW + HT+ S+ C+ E Q + TGS S
Sbjct: 1767 LSPDCRLLATVCLGGCLKLWDTVRGQLAFQHTYPK---SLNCVAFHPEGQVIATGSWAGS 1823
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ + + L V + A + +A V +V G DS V + + +GA + H
Sbjct: 1824 ISFFQVDGLKVTKDLGAPGASIRTLAFNVPGGVVAVGRLDSMVELWAWREGARLAAFPAH 1883
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
G V + + G +T +DG V W+
Sbjct: 1884 HGFVAAALFLHAGCQLLTAGEDGKVQVWS 1912
Score = 35.5 bits (78), Expect = 1.4
Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 8/135 (5%)
Query: 172 LIYGPDASGKTTLLTHLYTKCEEIFSKPVLRII--RFSASTPRSAYNLELLRVMCQQISI 229
L+ G GKT L L + + V ++ FS + P L LLR +C +
Sbjct: 1165 LVTGQSGQGKTAFLASLVSALQAPDGAKVASLVFFHFSGARPDQGLALTLLRRLCTYLRG 1224
Query: 230 ILNIPEGYLPKDASFDPLYINNWFQSLLRRCEEME-NEILFIFIDNVHRVNPLECDIVTG 288
L P G LP +++ L + L + E + + + ID R+ +++
Sbjct: 1225 QLKEP-GALP--STYRSLVWELQQRLLPKSAESLHPGQTQVLIIDGADRLVDQNGQLIS- 1280
Query: 289 LSWLPMSLPRNVFLV 303
W+P LPR V LV
Sbjct: 1281 -DWIPKKLPRCVHLV 1294
Score = 34.7 bits (76), Expect = 2.5
Identities = 41/163 (25%), Positives = 72/163 (44%), Gaps = 22/163 (13%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTR----ESQYLLTGSED 715
L+P G + + A +++ I S S+ G G L + V+ + L++G+ED
Sbjct: 1935 LSPDGDRVAVGYRADGIRIYKISSGSQ-----GAQGQALDVAVSALAWLSPKVLVSGAED 1989
Query: 716 TSVIVWDLHTLAVKTKIL--EHIAPVLCVAAIVNRSLVISGGDDSAV------IIT---S 764
S+ W L ++++ L PVL +A ++ L+ S +D V ++T
Sbjct: 1990 GSLQGWALKECSLQSLWLLSRFQKPVLGLAT--SQELLASASEDFTVQLWPRQLLTRPHK 2047
Query: 765 LVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
D T+L H G V+ DG TG +D ++ W+V
Sbjct: 2048 AEDFPCGTELRGHEGPVSCCSFSTDGGSLATGGRDRSLLCWDV 2090
Score = 33.5 bits (73), Expect = 5.7
Identities = 34/188 (18%), Positives = 72/188 (38%), Gaps = 8/188 (4%)
Query: 1073 NVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVS 1132
++ W + +V G SA + ++ + + DG + +W L G + +
Sbjct: 1704 DLRTWQEEKSVV-SGCDGISACLFLSDDTLFLTAFDG--LLELWDLQHGCRVLQTK---A 1757
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H +IT L+ D + + T + LK+W G+L+ + + CVA + +
Sbjct: 1758 HQYQITGCCLSPDCRLLATVCLGGCLKLWDTVRGQLA-FQHTYPKSLNCVAFHPEGQV-I 1815
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
+GSW ++ + ++ + + G + D + +W + G
Sbjct: 1816 ATGSWAGSISFFQVDGLKVTKDLGAPGASIRTLAFNVPGGVVAVGRLDSMVELWAWREGA 1875
Query: 1253 ALTSFSLH 1260
L +F H
Sbjct: 1876 RLAAFPAH 1883
>AY729024-1|AAU43731.1| 1052|Homo sapiens ubiquitin ligase
specificity factor protein.
Length = 1052
Score = 63.7 bits (148), Expect = 5e-09
Identities = 54/209 (25%), Positives = 96/209 (45%), Gaps = 9/209 (4%)
Query: 690 FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKIL-EHIAPVLCVAAIVNR 748
F+GH+GS+ + + E +LL+GS D S+ WDL + V T+I H + C+ NR
Sbjct: 449 FRGHAGSVRALFLCEEENFLLSGSYDLSIRYWDLKS-GVCTRIFGGHQGTITCMDLCKNR 507
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
++SGG D V + VD K H+ + + ++ + ++ + G V W++
Sbjct: 508 --LVSGGRDCQVKVWD-VDTGKCLKTFRHKDPILATRI--NDTYIVSSCERGLVKVWHIA 562
Query: 809 NFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFC 868
L+ T+ +G + + D LL+ D L + + G Y L K +
Sbjct: 563 MAQLVKTL-SGHEGAVKCLFFDQWHLLSGSTDG-LVMAWSMVGKYERCLMAFKHPKEVLD 620
Query: 869 VAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
V+ RV CAD +I +Y+ + ++
Sbjct: 621 VSLLFLRVISACADGKILIYNFLNGNCMK 649
Score = 60.9 bits (141), Expect = 3e-08
Identities = 46/180 (25%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Query: 679 WHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAP 738
W + S F GH G+I CM + + L++G D V VWD+ T K H P
Sbjct: 480 WDLKSGVCTRIFGGHQGTITCMDLCKNR--LVSGGRDCQVKVWDVDT-GKCLKTFRHKDP 536
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQ 798
+L A +N + ++S + V + + LV L H G+V + D ++GS
Sbjct: 537 IL--ATRINDTYIVSSCERGLVKVWHIAMAQLVKTLSGHEGAVKC--LFFDQWHLLSGST 592
Query: 799 DGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLK 858
DG V W++ + P + DV+ + +++ D ++ + F+ G + LK
Sbjct: 593 DGLVMAWSMVGKYERCLMAFKHPKEVLDVSLLFLRVISACADGKILIYNFLNGNCMKVLK 652
Score = 56.8 bits (131), Expect = 5e-07
Identities = 24/76 (31%), Positives = 43/76 (56%), Gaps = 3/76 (3%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
HA + L + +++GS D+S++ W L G +++ GH +TC+ + K ++
Sbjct: 452 HAGSVRALFLCEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLC---KNRL 508
Query: 1193 VSGSWDCNLIVWDINT 1208
VSG DC + VWD++T
Sbjct: 509 VSGGRDCQVKVWDVDT 524
Score = 56.0 bits (129), Expect = 9e-07
Identities = 47/200 (23%), Positives = 85/200 (42%), Gaps = 9/200 (4%)
Query: 1006 GHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRA 1065
GH G + + +LSGS D ++ W L + + GH I + + + R
Sbjct: 451 GHAGSVRALFLCEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLCKN--RL 508
Query: 1066 MSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+S R V VW VD+G L + + +N Y V S V++W +A ++
Sbjct: 509 VSGGRDCQVKVWDVDTGKCLKTFRHKDPILATRINDTYIVSSCERGLVKVWHIA---MAQ 565
Query: 1126 DNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVS 1185
+ H + C L D H+++GS D + W + GK + L+ + VS
Sbjct: 566 LVKTLSGHEGAVKC--LFFDQWHLLSGSTDGLVMAWSM-VGKYERCLMAFKHPKEVLDVS 622
Query: 1186 ITNKTQVVSGSWDCNLIVWD 1205
+ +V+S D +++++
Sbjct: 623 LL-FLRVISACADGKILIYN 641
Score = 50.8 bits (116), Expect = 4e-05
Identities = 24/55 (43%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
Query: 983 SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL 1037
S C RGLV+VW ++ +L TL+GH G + C+ F +L LSGS D V+ W +
Sbjct: 549 SSCERGLVKVWHIAMAQLVKTLSGHEGAVKCLFFDQWHL--LSGSTDGLVMAWSM 601
Score = 46.0 bits (104), Expect = 0.001
Identities = 35/162 (21%), Positives = 72/162 (44%), Gaps = 10/162 (6%)
Query: 1046 YKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAV 1105
++GH+ +++ L + + +S ++ W + SG+ G +I K +
Sbjct: 449 FRGHAGSVRALFLCEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLCKNRL 508
Query: 1106 LSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLD 1164
+S G D V++W + G + R H + I A + ++V+ +KVW +
Sbjct: 509 VSGGRDCQVKVWDVDTGKCLKTFR----HKDPI--LATRINDTYIVSSCERGLVKVWHIA 562
Query: 1165 GGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+L + L GH V C+ ++ ++SGS D ++ W +
Sbjct: 563 MAQLVKTLSGHEGAVKCL---FFDQWHLLSGSTDGLVMAWSM 601
Score = 43.2 bits (97), Expect = 0.007
Identities = 33/132 (25%), Positives = 55/132 (41%), Gaps = 6/132 (4%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
+R W L + GH G ITC+ N L +SG D V VW + T++
Sbjct: 477 IRYWDLKSGVCTRIFGGHQGTITCMDLCKNRL--VSGGRDCQVKVWDVDTGKCLKTFRHK 534
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDG 1109
+ T ++D S +R V VW + ++ + +G ++ ++ +LS
Sbjct: 535 DPILAT--RINDTYIVSSCERGL-VKVWHIAMAQLVKTLSGHEGAVKCLFFDQWHLLSGS 591
Query: 1110 -DNSVRIWSLAG 1120
D V WS+ G
Sbjct: 592 TDGLVMAWSMVG 603
Score = 43.2 bits (97), Expect = 0.007
Identities = 36/139 (25%), Positives = 65/139 (46%), Gaps = 7/139 (5%)
Query: 666 HLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT 725
++V + G ++WHI V T GH G++ C+ + +LL+GS D V+ W +
Sbjct: 546 YIVSSCERGLVKVWHIAMAQLVKTLSGHEGAVKCLFF--DQWHLLSGSTDGLVMAWSMVG 603
Query: 726 LAVKTKI-LEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD-HHRGSVTS 783
+ + +H VL V+ + R VIS D ++I + ++G + L + RG
Sbjct: 604 KYERCLMAFKHPKEVLDVSLLFLR--VISACADGKILIYNFLNGNCMKVLKANGRGDPVL 661
Query: 784 VKVIQDGNIFITGSQDGTV 802
IQ GN + ++ +
Sbjct: 662 SFFIQ-GNRMVVNTESNVL 679
Score = 34.7 bits (76), Expect = 2.5
Identities = 34/183 (18%), Positives = 72/183 (39%), Gaps = 7/183 (3%)
Query: 709 LLTGSEDTSVIVWDL-HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVD 767
L+ S + + + D+ A+ + H V + + ++SG D ++ L
Sbjct: 425 LIAVSSNRKIHLLDIIQVKAIPVEFRGHAGSVRALFLCEEENFLLSGSYDLSIRYWDLKS 484
Query: 768 GALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDV 827
G H+G++T + + + N ++G +D V W+V+ L T PI +
Sbjct: 485 GVCTRIFGGHQGTITCMDLCK--NRLVSGGRDCQVKVWDVDTGKCLKTFRHKDPILATRI 542
Query: 828 TDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYL 887
D ++++ + + + L H+ VK C+ D + G D +
Sbjct: 543 ND--TYIVSSCERGLVKVWHIAMAQLVKTLSGHEGAVK--CLFFDQWHLLSGSTDGLVMA 598
Query: 888 YSL 890
+S+
Sbjct: 599 WSM 601
Score = 33.9 bits (74), Expect = 4.3
Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 7/108 (6%)
Query: 1192 VVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
++SGS+D ++ WD+ + +TC+ + + VS D + +W+ G
Sbjct: 468 LLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLCKNR--LVSGGRDCQVKVWDVDTG 525
Query: 1252 LALTSFSLHVPLLGFQITSDCARVVVHLLDRGCLPIIWLHNTPATYVK 1299
L +F P+L +I +V +RG L +W H A VK
Sbjct: 526 KCLKTFRHKDPILATRIND---TYIVSSCERG-LVKVW-HIAMAQLVK 568
>AP001753-1|BAA95553.1| 919|Homo sapiens periodic tryptophan protein
2 homolog protein.
Length = 919
Score = 63.7 bits (148), Expect = 5e-09
Identities = 65/317 (20%), Positives = 122/317 (38%), Gaps = 8/317 (2%)
Query: 941 PTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRL 1000
P ++ K + K + ++ D ++ + L +G A G+ + +L L
Sbjct: 263 PAEEEKTGKVKYSRLAKYFFNKEGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNL 322
Query: 1001 QATLNGHIGHITCVTFSPNNLLVLSGSEDR-TVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
+L+ I V + + + G ++VW+ S L +GH +++ L
Sbjct: 323 IHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYS 382
Query: 1060 SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMK-YAVL-SDGDNSVRIW 1116
DG+ ++ V VW SG + T S+ + VT Y V+ S D +VR +
Sbjct: 383 PDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 1117 SLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD-MSLKVWKLDGGKLSQVLVGH 1175
L N + + +C A+ A + V G+ D + VW + G+L VL GH
Sbjct: 443 DLHRYRNF--RTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGH 500
Query: 1176 SDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAV 1235
++ + + K+ + S SWD + +WD+ V DG
Sbjct: 501 EGPISGLCFN-PMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRPDGAELA 559
Query: 1236 SCAEDKTLIIWETKRGL 1252
+ + W+ + +
Sbjct: 560 VATLNSQITFWDPENAV 576
Score = 61.3 bits (142), Expect = 2e-08
Identities = 47/228 (20%), Positives = 90/228 (39%), Gaps = 4/228 (1%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS-VIVWDLHT 725
LV ++G L + + +H+ SI + + ++ G ++VW+ +
Sbjct: 303 LVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQS 362
Query: 726 LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVK 785
+ K H ++ +A + +++GGDD V + + + G H VT V
Sbjct: 363 ESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVT 422
Query: 786 VIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDD---NVFLLTLQGDNE 842
G + +T S DGTV +++ + T T+ P V D + Q E
Sbjct: 423 FTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFE 482
Query: 843 LHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ + + TG L L H+ + C S +A D+ + L+ +
Sbjct: 483 IFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 60.1 bits (139), Expect = 6e-08
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 2/152 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L +P GQ++V G ++W+ +S TF HS + + T ++T S D +
Sbjct: 379 LAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGT 438
Query: 718 VIVWDLHTLA-VKTKILEHIAPVLCVAAIVNRSLVISGGDDS-AVIITSLVDGALVTKLD 775
V +DLH +T CVA + +V +G DS + + S+ G L+ L
Sbjct: 439 VRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLS 498
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
H G ++ + ++ + S D TV W++
Sbjct: 499 GHEGPISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 48.8 bits (111), Expect = 1e-04
Identities = 35/130 (26%), Positives = 53/130 (40%), Gaps = 3/130 (2%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H + A + D Q++VTG D +KVW G HS VT V + T V
Sbjct: 372 HFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYV-V 430
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXX-XXXKVTCVKVTGDGTIAVSCAEDK-TLIIWETKR 1250
V+ S D + +D++ + +CV V G I + A+D + +W +
Sbjct: 431 VTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQT 490
Query: 1251 GLALTSFSLH 1260
G L S H
Sbjct: 491 GRLLDVLSGH 500
Score = 48.4 bits (110), Expect = 2e-04
Identities = 46/224 (20%), Positives = 89/224 (39%), Gaps = 8/224 (3%)
Query: 962 EQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNL 1021
+Q + L S DGQ +G G V+VW + T H +T VTF+
Sbjct: 369 QQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGY 428
Query: 1022 LVLSGSEDRTVVVWQLADNSPSLTYKG-HSSAIQTLLMMSDGR-RAMSSDRARNVHVWLV 1079
+V++ S D TV + L T+ + + + + G + + + + VW +
Sbjct: 429 VVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSM 488
Query: 1080 DSGIVLHSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAER 1136
+G +L +G I + N +VL+ D +VR+W + +++ S A
Sbjct: 489 QTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALA 548
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVT 1180
+T D + +++ + W + + + G D+ T
Sbjct: 549 VT---FRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKT 589
Score = 42.3 bits (95), Expect = 0.012
Identities = 41/168 (24%), Positives = 70/168 (41%), Gaps = 12/168 (7%)
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
+Y V D V++W+ G H+ +T TA VVT SMD +++ +
Sbjct: 386 QYIVTGGDDGKVKVWNTLSGFCFVT---FTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 1162 KLDGGKLSQVLVGHSDI-VTCVAVSITNKTQVVSGSWDC-NLIVWDINTXXXXXXXXXXX 1219
L + + +CVAV + + V +G+ D + VW + T
Sbjct: 443 DLHRYRNFRTFTSPRPTQFSCVAVDASGEI-VSAGAQDSFEIFVWSMQTGRLLDVLSGHE 501
Query: 1220 XKVTCVKVTGDGTIAVSCAEDKTLIIWE------TKRGLALTSFSLHV 1261
++ + ++ S + DKT+ +W+ TK LALTS +L V
Sbjct: 502 GPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAV 549
Score = 33.1 bits (72), Expect = 7.5
Identities = 27/77 (35%), Positives = 35/77 (45%), Gaps = 5/77 (6%)
Query: 1135 ERITCFALTADSQHVVTGSMDMSLKVWKLD--GGKLSQVLVGHSD-IVTCVAVSITNKTQ 1191
+ TC T DS+ V GS DMS V+ + + L GH D IV C S N
Sbjct: 145 DETTCIDWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKDAIVACFFES--NSLD 202
Query: 1192 VVSGSWDCNLIVWDINT 1208
+ S S D L +W +T
Sbjct: 203 LYSLSQDGVLCMWQCDT 219
>AF127799-1|AAP97249.1| 305|Homo sapiens G protein beta subunit-like
protein protein.
Length = 305
Score = 63.7 bits (148), Expect = 5e-09
Identities = 68/270 (25%), Positives = 111/270 (41%), Gaps = 9/270 (3%)
Query: 983 SGCARGLVRVWQLSTHRL--QATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN 1040
+G LV+VW+ RL Q +L GH + V S + S S D + + L +
Sbjct: 37 TGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLRDLENG 96
Query: 1041 SPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA---SIDV 1097
+ TL D + + V+++ V+SG +S SI
Sbjct: 97 KQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAY 156
Query: 1098 TLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMS 1157
+ + KY D + I+++A G HA I + DSQ +VT S D
Sbjct: 157 SPDGKYLASGAIDGIINIFAIATGKLLHTLE---GHAMPIRSLTFSPDSQLLVTASDDGY 213
Query: 1158 LKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXX 1217
+K++ + L+ L GH+ V VA + T VS S D ++ V D+ T
Sbjct: 214 IKIYDVQHANLAGTLSGHASWVLNVAF-CPDDTHFVSSSSDKSVKVRDVGTRTCVHTFFD 272
Query: 1218 XXXKVTCVKVTGDGTIAVSCAEDKTLIIWE 1247
+V VK G+G+ VS +D+ + I++
Sbjct: 273 HQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302
Score = 60.1 bits (139), Expect = 6e-08
Identities = 33/119 (27%), Positives = 64/119 (53%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
I + S DG+ ASG G++ ++ ++T +L TL GH I +TFSP++ L+++ S+
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFAIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASD 210
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHS 1087
D + ++ + + + T GH+S + + D +SS ++V V V + +H+
Sbjct: 211 DGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVRDVGTRTCVHT 269
Score = 54.4 bits (125), Expect = 3e-06
Identities = 42/186 (22%), Positives = 85/186 (45%), Gaps = 3/186 (1%)
Query: 705 ESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITS 764
+SQYL TG+ V ++ + + + + +L +A + + SG D + I +
Sbjct: 117 DSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFA 176
Query: 765 LVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVT--AGVPI 822
+ G L+ L+ H + S+ D + +T S DG + ++V++ L T++ A +
Sbjct: 177 IATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVL 236
Query: 823 HIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCAD 882
++ DD F+ + D + +R T T +H H+ +V + S++ D
Sbjct: 237 NVAFCPDDTHFVSS-SSDKSVKVRDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDD 295
Query: 883 QRIYLY 888
Q I++Y
Sbjct: 296 QEIHIY 301
Score = 50.8 bits (116), Expect = 4e-05
Identities = 28/120 (23%), Positives = 55/120 (45%)
Query: 958 LLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFS 1017
LL + +PI L S D QL + G ++++ + L TL+GH + V F
Sbjct: 182 LLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFC 241
Query: 1018 PNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
P++ +S S D++V V + + T+ H + + +G + +S + +H++
Sbjct: 242 PDDTHFVSSSSDKSVKVRDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIY 301
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/139 (23%), Positives = 64/139 (46%)
Query: 661 APSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+P G++L G ++ I + +HT +GH+ I + + +SQ L+T S+D + +
Sbjct: 157 SPDGKYLASGAIDGIINIFAIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKI 216
Query: 721 WDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
+D+ + + H + VL VA + + +S D +V + + V H+
Sbjct: 217 YDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVRDVGTRTCVHTFFDHQDQ 276
Query: 781 VTSVKVIQDGNIFITGSQD 799
V VK +G+ ++ D
Sbjct: 277 VWGVKYNGNGSKIVSVGDD 295
Score = 47.2 bits (107), Expect = 4e-04
Identities = 48/245 (19%), Positives = 107/245 (43%), Gaps = 5/245 (2%)
Query: 1019 NNLLVLSGSEDRTVVVWQLADNSPSLTY--KGHSSAIQTLLMMSDGRRAMSSDRARNVHV 1076
N+ V++GS D V VW+ D L + +GH + ++ + A SS ++ +
Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRL 90
Query: 1077 WLVDSGIVLHSA-TGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE 1135
+++G + S GP + + + L+ G + ++ ++ G ++ + + +
Sbjct: 91 RDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKV-NIFGVESGKKEYSLDTRGK 149
Query: 1136 RITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSG 1195
I A + D +++ +G++D + ++ + GKL L GH+ + + S + +V+
Sbjct: 150 FILSIAYSPDGKYLASGAIDGIINIFAIATGKLLHTLEGHAMPIRSLTFS-PDSQLLVTA 208
Query: 1196 SWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGLALT 1255
S D + ++D+ V V D T VS + DK++ + + +
Sbjct: 209 SDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVRDVGTRTCVH 268
Query: 1256 SFSLH 1260
+F H
Sbjct: 269 TFFDH 273
Score = 40.3 bits (90), Expect = 0.050
Identities = 43/237 (18%), Positives = 96/237 (40%), Gaps = 7/237 (2%)
Query: 972 LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRT 1031
+++S + AS +R+ L + +++ + FSP++ + +G+
Sbjct: 70 VDISHTLPIAASSSLDAHIRLRDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGK 129
Query: 1032 VVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATG- 1090
V ++ + + I ++ DG+ S ++++ + +G +LH+ G
Sbjct: 130 VNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFAIATGKLLHTLEGH 189
Query: 1091 --PSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQH 1148
P S+ + + + V + D ++I+ + ++ HA + A D H
Sbjct: 190 AMPIRSLTFSPDSQLLVTASDDGYIKIYDV---QHANLAGTLSGHASWVLNVAFCPDDTH 246
Query: 1149 VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
V+ S D S+KV + H D V V + N +++VS D + ++D
Sbjct: 247 FVSSSSDKSVKVRDVGTRTCVHTFFDHQDQVWGVKYN-GNGSKIVSVGDDQEIHIYD 302
Score = 39.1 bits (87), Expect = 0.11
Identities = 32/161 (19%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Query: 960 QAEQSDLIPISC--LEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFS 1017
Q + D P+ L S D Q A+G G V ++ + + + + +L+ I + +S
Sbjct: 98 QIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYS 157
Query: 1018 PNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
P+ + SG+ D + ++ +A T +GH+ I++L D + +++ + ++
Sbjct: 158 PDGKYLASGAIDGIINIFAIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIY 217
Query: 1078 LVDSGIVLHSATGPSA---SIDVTLNMKYAVLSDGDNSVRI 1115
V + + +G ++ ++ + + V S D SV++
Sbjct: 218 DVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKV 258
>AB209669-1|BAD92906.1| 1903|Homo sapiens Telomerase protein component
1 variant protein.
Length = 1903
Score = 63.7 bits (148), Expect = 5e-09
Identities = 62/271 (22%), Positives = 114/271 (42%), Gaps = 12/271 (4%)
Query: 1004 LNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL-ADNSPSLTYK---GHSSAIQTLLMM 1059
L GH G ++C +FS + + +G DR+++ W + +P L + H +
Sbjct: 1399 LRGHEGPVSCCSFSTDGGSLATGGRDRSLLCWDVRTPKTPVLIHSFPACHRDWVTGCAWT 1458
Query: 1060 SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLS-DGDNSVRIWSL 1118
D +S +V +W +SG L G +++ ++ V+S D ++++W
Sbjct: 1459 KD-NLLISCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVAAVEEHVVSVSRDGTLKVWDH 1517
Query: 1119 AGGDNSEDNRRS--VSH---AERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLV 1173
G + + S +SH A VVT +D + ++W + L+
Sbjct: 1518 QGVELTSIPAHSGPISHCAAAMEPRAAGQPGSELLVVTVGLDGATRLWHPLLVCQTHTLL 1577
Query: 1174 GHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTI 1233
GHS V AVS T+ +++ S D ++ +W + VT V DG++
Sbjct: 1578 GHSGPVRAAAVSETSGL-MLTASEDGSVRLWQVPKEADDTCIPRSSAAVTAVAWAPDGSM 1636
Query: 1234 AVSCAEDKTLIIWETKRGLALTSFSLHVPLL 1264
AVS + LI+W+ + +A H+ L
Sbjct: 1637 AVSGNQAGELILWQEAKAVATAQAPGHIGAL 1667
Score = 60.5 bits (140), Expect = 4e-08
Identities = 44/176 (25%), Positives = 75/176 (42%), Gaps = 7/176 (3%)
Query: 662 PSGQHLVLAPSA-GDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
P + LV+ G +LWH + + HT GHSG + V+ S +LT SED SV +
Sbjct: 1547 PGSELLVVTVGLDGATRLWHPLLVCQTHTLLGHSGPVRAAAVSETSGLMLTASEDGSVRL 1606
Query: 721 WDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGS 780
W + A T I A V VA + S+ +SG +I+ + H G+
Sbjct: 1607 WQVPKEADDTCIPRSSAAVTAVAWAPDGSMAVSGNQAGELILWQEAKAVATAQAPGHIGA 1666
Query: 781 VTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLT 836
+ + + F S D + W V+ + + +H+ + +++ +LT
Sbjct: 1667 L----IWSSAHTFFVLSADEKISEWQVK--LRKGSAPGNLSLHLNRILQEDLGVLT 1716
Score = 52.8 bits (121), Expect = 9e-06
Identities = 36/137 (26%), Positives = 64/137 (46%), Gaps = 9/137 (6%)
Query: 691 KGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPV-----LCVAAI 745
+GH G + C + + L TG D S++ WD+ T KT +L H P + A
Sbjct: 1400 RGHEGPVSCCSFSTDGGSLATGGRDRSLLCWDVRT--PKTPVLIHSFPACHRDWVTGCAW 1457
Query: 746 VNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTW 805
+L+IS D +V + G + + H+ +V++V +++ + + S+DGT+ W
Sbjct: 1458 TKDNLLISCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVAAVEEHVVSV--SRDGTLKVW 1515
Query: 806 NVENFTLLSTVTAGVPI 822
+ + L S PI
Sbjct: 1516 DHQGVELTSIPAHSGPI 1532
Score = 52.0 bits (119), Expect = 2e-05
Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 20/154 (12%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTL 726
L+ S G LW S ++ F GH ++ + E ++++ S D ++ VWD H
Sbjct: 1463 LISCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVAAVEE--HVVSVSRDGTLKVWD-HQG 1519
Query: 727 AVKTKILEHIAPVL-CVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDH--------- 776
T I H P+ C AA+ R+ G + +++T +DGA T+L H
Sbjct: 1520 VELTSIPAHSGPISHCAAAMEPRAAGQPGSE--LLVVTVGLDGA--TRLWHPLLVCQTHT 1575
Query: 777 ---HRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
H G V + V + + +T S+DG+V W V
Sbjct: 1576 LLGHSGPVRAAAVSETSGLMLTASEDGSVRLWQV 1609
Score = 50.0 bits (114), Expect = 6e-05
Identities = 37/150 (24%), Positives = 62/150 (41%), Gaps = 2/150 (1%)
Query: 988 GLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYK 1047
G R+W TL GH G + S + L+L+ SED +V +WQ+ +
Sbjct: 1560 GATRLWHPLLVCQTHTLLGHSGPVRAAAVSETSGLMLTASEDGSVRLWQVPKEADDTCIP 1619
Query: 1048 GHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLS 1107
S+A+ + DG A+S ++A + +W + A G ++ + + VLS
Sbjct: 1620 RSSAAVTAVAWAPDGSMAVSGNQAGELILWQEAKAVATAQAPGHIGALIWSSAHTFFVLS 1679
Query: 1108 DGDNSVRIWSLAGGDNSEDNRRSVSHAERI 1137
D + W + S S+ H RI
Sbjct: 1680 -ADEKISEWQVKLRKGSAPGNLSL-HLNRI 1707
Score = 47.2 bits (107), Expect = 4e-04
Identities = 71/312 (22%), Positives = 128/312 (41%), Gaps = 30/312 (9%)
Query: 968 PISCLEVSRD-GQLGASGCARGLVRVWQLSTHRLQATLNG----HIGHITCVTFSPNNLL 1022
P+SC S D G L G R L+ W + T + ++ H +T ++ +NLL
Sbjct: 1405 PVSCCSFSTDGGSLATGGRDRSLL-CWDVRTPKTPVLIHSFPACHRDWVTGCAWTKDNLL 1463
Query: 1023 VLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNV--HVWLVD 1080
+ S S D +V +W + GH SA+ + + + ++S D V H +
Sbjct: 1464 I-SCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVAAVEEHVVSVSRDGTLKVWDHQGVEL 1522
Query: 1081 SGIVLHSATGPSASIDVTLNMKYA--------VLSDG-DNSVRIWSLAGGDNSEDNRRSV 1131
+ I HS GP + + + A V++ G D + R+W +
Sbjct: 1523 TSIPAHS--GPISHCAAAMEPRAAGQPGSELLVVTVGLDGATRLWHPL---LVCQTHTLL 1577
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQ 1191
H+ + A++ S ++T S D S+++W++ + S VT VA + + +
Sbjct: 1578 GHSGPVRAAAVSETSGLMLTASEDGSVRLWQVPKEADDTCIPRSSAAVTAVAWA-PDGSM 1636
Query: 1192 VVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK-- 1249
VSG+ LI+W + + + T V A++K + W+ K
Sbjct: 1637 AVSGNQAGELILWQ---EAKAVATAQAPGHIGALIWSSAHTFFVLSADEK-ISEWQVKLR 1692
Query: 1250 RGLALTSFSLHV 1261
+G A + SLH+
Sbjct: 1693 KGSAPGNLSLHL 1704
Score = 42.7 bits (96), Expect = 0.009
Identities = 63/295 (21%), Positives = 113/295 (38%), Gaps = 20/295 (6%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
++C+ +GQ+ A+G G + +Q+ ++ L I + F+ +V G
Sbjct: 1145 LNCVAFHPEGQVIATGSWAGSISFFQVDGLKVTKDLGAPGASIRTLAFNVPGGVVAVGRL 1204
Query: 1029 DRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSA 1088
D V +W + + + H + L + G + +++ V VW SG L
Sbjct: 1205 DSMVELWAWREGARLAAFPAHHGFVAAALFLHAGCQLLTAGEDGKVQVW---SG-SLGRP 1260
Query: 1089 TGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDN----SEDNRRSVSHAERITCFALTA 1144
G S+ ++ + A+ DGD V + A G S ++ + A + AL
Sbjct: 1261 RGHLGSLSLSPALSVALSPDGDR-VAVGYRADGIRIYKISSGSQGAQGQALDVAVSALAW 1319
Query: 1145 DSQHV-VTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIV 1203
S V V+G+ D SL+ W L L Q L S V T++ + S S D + +
Sbjct: 1320 LSPKVLVSGAEDGSLQGWALKECSL-QSLWLLSRFQKPVLGLATSQELLASASEDFTVQL 1378
Query: 1204 WDINTXXX---------XXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
W V+C + DG + D++L+ W+ +
Sbjct: 1379 WPRQLLTRPHKAEDFPCGTELRGHEGPVSCCSFSTDGGSLATGGRDRSLLCWDVR 1433
Score = 42.3 bits (95), Expect = 0.012
Identities = 38/149 (25%), Positives = 61/149 (40%), Gaps = 5/149 (3%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKV--HTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L+P Q L G +LW + HT+ S+ C+ E Q + TGS S
Sbjct: 1109 LSPDCQLLATVCLGGCLKLWDTVRGQLAFQHTYPK---SLNCVAFHPEGQVIATGSWAGS 1165
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+ + + L V + A + +A V +V G DS V + + +GA + H
Sbjct: 1166 ISFFQVDGLKVTKDLGAPGASIRTLAFNVPGGVVAVGRLDSMVELWAWREGARLAAFPAH 1225
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
G V + + G +T +DG V W+
Sbjct: 1226 HGFVAAALFLHAGCQLLTAGEDGKVQVWS 1254
Score = 35.1 bits (77), Expect = 1.9
Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 8/135 (5%)
Query: 172 LIYGPDASGKTTLLTHLYTKCEEIFSKPVLRII--RFSASTPRSAYNLELLRVMCQQISI 229
L+ G GKT L L + + V ++ FS + P L LLR +C +
Sbjct: 514 LVTGQSGQGKTAFLASLVSALQAPDGAKVAPLVFFHFSGARPDQGLALTLLRRLCTYLRG 573
Query: 230 ILNIPEGYLPKDASFDPLYINNWFQSLLRRCEEME-NEILFIFIDNVHRVNPLECDIVTG 288
L P G LP +++ L + L + E + + + ID R+ +++
Sbjct: 574 QLKEP-GALP--STYRSLVWELQQRLLPKSAESLHPGQTQVLIIDGADRLVDQNGQLIS- 629
Query: 289 LSWLPMSLPRNVFLV 303
W+P LPR V LV
Sbjct: 630 -DWIPKKLPRCVHLV 643
Score = 35.1 bits (77), Expect = 1.9
Identities = 35/188 (18%), Positives = 72/188 (38%), Gaps = 8/188 (4%)
Query: 1073 NVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVS 1132
++ W + +V G SA + ++ + + DG + +W L G + +
Sbjct: 1046 DLRTWQEEKSVV-SGCDGISACLFLSDDTLFLTAFDG--LLELWDLQHGCRVLQTK---A 1099
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H +IT L+ D Q + T + LK+W G+L+ + + CVA + +
Sbjct: 1100 HQYQITGCCLSPDCQLLATVCLGGCLKLWDTVRGQLA-FQHTYPKSLNCVAFHPEGQV-I 1157
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRGL 1252
+GSW ++ + ++ + + G + D + +W + G
Sbjct: 1158 ATGSWAGSISFFQVDGLKVTKDLGAPGASIRTLAFNVPGGVVAVGRLDSMVELWAWREGA 1217
Query: 1253 ALTSFSLH 1260
L +F H
Sbjct: 1218 RLAAFPAH 1225
Score = 34.7 bits (76), Expect = 2.5
Identities = 41/163 (25%), Positives = 72/163 (44%), Gaps = 22/163 (13%)
Query: 660 LAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTR----ESQYLLTGSED 715
L+P G + + A +++ I S S+ G G L + V+ + L++G+ED
Sbjct: 1277 LSPDGDRVAVGYRADGIRIYKISSGSQ-----GAQGQALDVAVSALAWLSPKVLVSGAED 1331
Query: 716 TSVIVWDLHTLAVKTKIL--EHIAPVLCVAAIVNRSLVISGGDDSAV------IIT---S 764
S+ W L ++++ L PVL +A ++ L+ S +D V ++T
Sbjct: 1332 GSLQGWALKECSLQSLWLLSRFQKPVLGLAT--SQELLASASEDFTVQLWPRQLLTRPHK 1389
Query: 765 LVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
D T+L H G V+ DG TG +D ++ W+V
Sbjct: 1390 AEDFPCGTELRGHEGPVSCCSFSTDGGSLATGGRDRSLLCWDV 1432
Score = 33.5 bits (73), Expect = 5.7
Identities = 38/146 (26%), Positives = 56/146 (38%), Gaps = 7/146 (4%)
Query: 663 SGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWD 722
S L L G +LW + +V K H I C++ + Q L T + +WD
Sbjct: 1070 SDDTLFLTAFDGLLELWDLQHGCRVLQTKAHQYQITGCCLSPDCQLLATVCLGGCLKLWD 1129
Query: 723 LHTLAVKTKI-LEHIAP-VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTK-LDHHRG 779
V+ ++ +H P L A VI+ G + I VDG VTK L
Sbjct: 1130 ----TVRGQLAFQHTYPKSLNCVAFHPEGQVIATGSWAGSISFFQVDGLKVTKDLGAPGA 1185
Query: 780 SVTSVKVIQDGNIFITGSQDGTVCTW 805
S+ ++ G + G D V W
Sbjct: 1186 SIRTLAFNVPGGVVAVGRLDSMVELW 1211
>AB001517-2|BAA21137.1| 919|Homo sapiens PWP2 protein protein.
Length = 919
Score = 63.7 bits (148), Expect = 5e-09
Identities = 65/317 (20%), Positives = 122/317 (38%), Gaps = 8/317 (2%)
Query: 941 PTKQMKRRQTKSTTNITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRL 1000
P ++ K + K + ++ D ++ + L +G A G+ + +L L
Sbjct: 263 PAEEEKTGKVKYSRLAKYFFNKEGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNL 322
Query: 1001 QATLNGHIGHITCVTFSPNNLLVLSGSEDR-TVVVWQLADNSPSLTYKGHSSAIQTLLMM 1059
+L+ I V + + + G ++VW+ S L +GH +++ L
Sbjct: 323 IHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYS 382
Query: 1060 SDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI-DVTLNMK-YAVL-SDGDNSVRIW 1116
DG+ ++ V VW SG + T S+ + VT Y V+ S D +VR +
Sbjct: 383 PDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 1117 SLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMD-MSLKVWKLDGGKLSQVLVGH 1175
L N + + +C A+ A + V G+ D + VW + G+L VL GH
Sbjct: 443 DLHRYRNF--RTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGH 500
Query: 1176 SDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAV 1235
++ + + K+ + S SWD + +WD+ V DG
Sbjct: 501 EGPISGLCFN-PMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRPDGAELA 559
Query: 1236 SCAEDKTLIIWETKRGL 1252
+ + W+ + +
Sbjct: 560 VATLNSQITFWDPENAV 576
Score = 61.3 bits (142), Expect = 2e-08
Identities = 47/228 (20%), Positives = 90/228 (39%), Gaps = 4/228 (1%)
Query: 667 LVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS-VIVWDLHT 725
LV ++G L + + +H+ SI + + ++ G ++VW+ +
Sbjct: 303 LVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQS 362
Query: 726 LAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVK 785
+ K H ++ +A + +++GGDD V + + + G H VT V
Sbjct: 363 ESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVT 422
Query: 786 VIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVTDD---NVFLLTLQGDNE 842
G + +T S DGTV +++ + T T+ P V D + Q E
Sbjct: 423 FTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFE 482
Query: 843 LHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSL 890
+ + + TG L L H+ + C S +A D+ + L+ +
Sbjct: 483 IFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 60.1 bits (139), Expect = 6e-08
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 2/152 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L +P GQ++V G ++W+ +S TF HS + + T ++T S D +
Sbjct: 379 LAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGT 438
Query: 718 VIVWDLHTLA-VKTKILEHIAPVLCVAAIVNRSLVISGGDDS-AVIITSLVDGALVTKLD 775
V +DLH +T CVA + +V +G DS + + S+ G L+ L
Sbjct: 439 VRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLS 498
Query: 776 HHRGSVTSVKVIQDGNIFITGSQDGTVCTWNV 807
H G ++ + ++ + S D TV W++
Sbjct: 499 GHEGPISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 48.8 bits (111), Expect = 1e-04
Identities = 35/130 (26%), Positives = 53/130 (40%), Gaps = 3/130 (2%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
H + A + D Q++VTG D +KVW G HS VT V + T V
Sbjct: 372 HFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYV-V 430
Query: 1193 VSGSWDCNLIVWDINTXXXXXXXXX-XXXKVTCVKVTGDGTIAVSCAEDK-TLIIWETKR 1250
V+ S D + +D++ + +CV V G I + A+D + +W +
Sbjct: 431 VTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQT 490
Query: 1251 GLALTSFSLH 1260
G L S H
Sbjct: 491 GRLLDVLSGH 500
Score = 48.4 bits (110), Expect = 2e-04
Identities = 46/224 (20%), Positives = 89/224 (39%), Gaps = 8/224 (3%)
Query: 962 EQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNL 1021
+Q + L S DGQ +G G V+VW + T H +T VTF+
Sbjct: 369 QQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGY 428
Query: 1022 LVLSGSEDRTVVVWQLADNSPSLTYKG-HSSAIQTLLMMSDGR-RAMSSDRARNVHVWLV 1079
+V++ S D TV + L T+ + + + + G + + + + VW +
Sbjct: 429 VVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSM 488
Query: 1080 DSGIVLHSATGPSASID-VTLNMKYAVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHAER 1136
+G +L +G I + N +VL+ D +VR+W + +++ S A
Sbjct: 489 QTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALA 548
Query: 1137 ITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVT 1180
+T D + +++ + W + + + G D+ T
Sbjct: 549 VT---FRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKT 589
Score = 42.3 bits (95), Expect = 0.012
Identities = 41/168 (24%), Positives = 70/168 (41%), Gaps = 12/168 (7%)
Query: 1102 KYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVW 1161
+Y V D V++W+ G H+ +T TA VVT SMD +++ +
Sbjct: 386 QYIVTGGDDGKVKVWNTLSGFCFVT---FTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 1162 KLDGGKLSQVLVGHSDI-VTCVAVSITNKTQVVSGSWDC-NLIVWDINTXXXXXXXXXXX 1219
L + + +CVAV + + V +G+ D + VW + T
Sbjct: 443 DLHRYRNFRTFTSPRPTQFSCVAVDASGEI-VSAGAQDSFEIFVWSMQTGRLLDVLSGHE 501
Query: 1220 XKVTCVKVTGDGTIAVSCAEDKTLIIWE------TKRGLALTSFSLHV 1261
++ + ++ S + DKT+ +W+ TK LALTS +L V
Sbjct: 502 GPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAV 549
Score = 33.1 bits (72), Expect = 7.5
Identities = 27/77 (35%), Positives = 35/77 (45%), Gaps = 5/77 (6%)
Query: 1135 ERITCFALTADSQHVVTGSMDMSLKVWKLD--GGKLSQVLVGHSD-IVTCVAVSITNKTQ 1191
+ TC T DS+ V GS DMS V+ + + L GH D IV C S N
Sbjct: 145 DETTCIDWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKDAIVACFFES--NSLD 202
Query: 1192 VVSGSWDCNLIVWDINT 1208
+ S S D L +W +T
Sbjct: 203 LYSLSQDGVLCMWQCDT 219
>BC028364-1|AAH28364.1| 1061|Homo sapiens FBXW10 protein protein.
Length = 1061
Score = 63.3 bits (147), Expect = 6e-09
Identities = 54/209 (25%), Positives = 96/209 (45%), Gaps = 9/209 (4%)
Query: 690 FKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKIL-EHIAPVLCVAAIVNR 748
F+GH+GS+ + + E +LL+GS D S+ WDL + V T+I H + C+ NR
Sbjct: 478 FRGHAGSVRALFLCEEENFLLSGSYDLSIRYWDLKS-GVCTRIFGGHQGTITCMDLCKNR 536
Query: 749 SLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVE 808
++SGG D V + VD K H+ + + ++ + ++ + G V W++
Sbjct: 537 --LVSGGRDCQVKVWD-VDTGKCLKTFRHKDPILATRI--NDTYIVSSCERGLVKVWHIA 591
Query: 809 NFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFC 868
L+ T+ +G + + D LL+ D L + + G Y L K +
Sbjct: 592 MAQLVKTL-SGHEGAVKCLFFDQWHLLSGSTDG-LVMAWSMVGKYERCLMAFKHPKEVLD 649
Query: 869 VAHDSSRVAVGCADQRIYLYSLHSAQLLR 897
V+ RV CAD +I +Y+ + ++
Sbjct: 650 VSLLFLRVISACADGKIRIYNFLNGNCMK 678
Score = 62.1 bits (144), Expect = 1e-08
Identities = 46/180 (25%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Query: 679 WHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAP 738
W + S F GH G+I CM + + L++G D V VWD+ T K H P
Sbjct: 509 WDLKSGVCTRIFGGHQGTITCMDLCKNR--LVSGGRDCQVKVWDVDT-GKCLKTFRHKDP 565
Query: 739 VLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQ 798
+L A +N + ++S + V + + LV L H G+V + D ++GS
Sbjct: 566 IL--ATRINDTYIVSSCERGLVKVWHIAMAQLVKTLSGHEGAVKC--LFFDQWHLLSGST 621
Query: 799 DGTVCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLK 858
DG V W++ + P + DV+ + +++ D ++ + F+ G + LK
Sbjct: 622 DGLVMAWSMVGKYERCLMAFKHPKEVLDVSLLFLRVISACADGKIRIYNFLNGNCMKVLK 681
Score = 56.8 bits (131), Expect = 5e-07
Identities = 24/76 (31%), Positives = 43/76 (56%), Gaps = 3/76 (3%)
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
HA + L + +++GS D+S++ W L G +++ GH +TC+ + K ++
Sbjct: 481 HAGSVRALFLCEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLC---KNRL 537
Query: 1193 VSGSWDCNLIVWDINT 1208
VSG DC + VWD++T
Sbjct: 538 VSGGRDCQVKVWDVDT 553
Score = 54.8 bits (126), Expect = 2e-06
Identities = 40/160 (25%), Positives = 67/160 (41%), Gaps = 7/160 (4%)
Query: 1006 GHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRA 1065
GH G + + +LSGS D ++ W L + + GH I + + + R
Sbjct: 480 GHAGSVRALFLCEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLCKN--RL 537
Query: 1066 MSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSE 1125
+S R V VW VD+G L + + +N Y V S V++W +A ++
Sbjct: 538 VSGGRDCQVKVWDVDTGKCLKTFRHKDPILATRINDTYIVSSCERGLVKVWHIA---MAQ 594
Query: 1126 DNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDG 1165
+ H + C L D H+++GS D + W + G
Sbjct: 595 LVKTLSGHEGAVKC--LFFDQWHLLSGSTDGLVMAWSMVG 632
Score = 50.8 bits (116), Expect = 4e-05
Identities = 24/55 (43%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
Query: 983 SGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQL 1037
S C RGLV+VW ++ +L TL+GH G + C+ F +L LSGS D V+ W +
Sbjct: 578 SSCERGLVKVWHIAMAQLVKTLSGHEGAVKCLFFDQWHL--LSGSTDGLVMAWSM 630
Score = 46.0 bits (104), Expect = 0.001
Identities = 35/162 (21%), Positives = 72/162 (44%), Gaps = 10/162 (6%)
Query: 1046 YKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAV 1105
++GH+ +++ L + + +S ++ W + SG+ G +I K +
Sbjct: 478 FRGHAGSVRALFLCEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLCKNRL 537
Query: 1106 LSDG-DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLD 1164
+S G D V++W + G + R H + I A + ++V+ +KVW +
Sbjct: 538 VSGGRDCQVKVWDVDTGKCLKTFR----HKDPI--LATRINDTYIVSSCERGLVKVWHIA 591
Query: 1165 GGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDI 1206
+L + L GH V C+ ++ ++SGS D ++ W +
Sbjct: 592 MAQLVKTLSGHEGAVKCL---FFDQWHLLSGSTDGLVMAWSM 630
Score = 44.0 bits (99), Expect = 0.004
Identities = 41/184 (22%), Positives = 74/184 (40%), Gaps = 10/184 (5%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGH 1049
+R W L + GH G ITC+ N L +SG D V VW + T++
Sbjct: 506 IRYWDLKSGVCTRIFGGHQGTITCMDLCKNRL--VSGGRDCQVKVWDVDTGKCLKTFRHK 563
Query: 1050 SSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTLNMKYAVLSDG 1109
+ T ++D S +R V VW + ++ + +G ++ ++ +LS
Sbjct: 564 DPILAT--RINDTYIVSSCERGL-VKVWHIAMAQLVKTLSGHEGAVKCLFFDQWHLLSGS 620
Query: 1110 -DNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKL 1168
D V WS+ G E + H + + +L V++ D ++++ G
Sbjct: 621 TDGLVMAWSMVG--KYERCLMAFKHPKEVLDVSLL--FLRVISACADGKIRIYNFLNGNC 676
Query: 1169 SQVL 1172
+VL
Sbjct: 677 MKVL 680
Score = 41.1 bits (92), Expect = 0.028
Identities = 36/139 (25%), Positives = 64/139 (46%), Gaps = 7/139 (5%)
Query: 666 HLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHT 725
++V + G ++WHI V T GH G++ C+ + +LL+GS D V+ W +
Sbjct: 575 YIVSSCERGLVKVWHIAMAQLVKTLSGHEGAVKCLFF--DQWHLLSGSTDGLVMAWSMVG 632
Query: 726 LAVKTKI-LEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLD-HHRGSVTS 783
+ + +H VL V+ + R VIS D + I + ++G + L + RG
Sbjct: 633 KYERCLMAFKHPKEVLDVSLLFLR--VISACADGKIRIYNFLNGNCMKVLKANGRGDPVL 690
Query: 784 VKVIQDGNIFITGSQDGTV 802
IQ GN + ++ +
Sbjct: 691 SFFIQ-GNRMVVNTESNVL 708
Score = 34.7 bits (76), Expect = 2.5
Identities = 34/183 (18%), Positives = 72/183 (39%), Gaps = 7/183 (3%)
Query: 709 LLTGSEDTSVIVWDL-HTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVD 767
L+ S + + + D+ A+ + H V + + ++SG D ++ L
Sbjct: 454 LIAVSSNRKIHLLDIIQVKAIPVEFRGHAGSVRALFLCEEENFLLSGSYDLSIRYWDLKS 513
Query: 768 GALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDV 827
G H+G++T + + + N ++G +D V W+V+ L T PI +
Sbjct: 514 GVCTRIFGGHQGTITCMDLCK--NRLVSGGRDCQVKVWDVDTGKCLKTFRHKDPILATRI 571
Query: 828 TDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYL 887
D ++++ + + + L H+ VK C+ D + G D +
Sbjct: 572 ND--TYIVSSCERGLVKVWHIAMAQLVKTLSGHEGAVK--CLFFDQWHLLSGSTDGLVMA 627
Query: 888 YSL 890
+S+
Sbjct: 628 WSM 630
Score = 33.9 bits (74), Expect = 4.3
Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 7/108 (6%)
Query: 1192 VVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWETKRG 1251
++SGS+D ++ WD+ + +TC+ + + VS D + +W+ G
Sbjct: 497 LLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLCKNR--LVSGGRDCQVKVWDVDTG 554
Query: 1252 LALTSFSLHVPLLGFQITSDCARVVVHLLDRGCLPIIWLHNTPATYVK 1299
L +F P+L +I +V +RG L +W H A VK
Sbjct: 555 KCLKTFRHKDPILATRIND---TYIVSSCERG-LVKVW-HIAMAQLVK 597
>X70476-1|CAA49900.1| 906|Homo sapiens subunit of coatomer complex
protein.
Length = 906
Score = 62.9 bits (146), Expect = 8e-09
Identities = 48/221 (21%), Positives = 92/221 (41%), Gaps = 11/221 (4%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN-SPSLTYKG 1048
+RV+ +T H +I C+ P +L+ S+D + +W S S ++G
Sbjct: 81 IRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEG 140
Query: 1049 HSSAI-QTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL-----NMK 1102
H+ + Q ++ D + S+ R + VW + S + G ++ +
Sbjct: 141 HTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKP 200
Query: 1103 YAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWK 1162
Y + D V+IW N + HA+ ++C + + ++TGS D ++++W
Sbjct: 201 YLISGADDRLVKIWDY---QNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWH 257
Query: 1163 LDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIV 1203
+L L + V CVA S+ V G + ++IV
Sbjct: 258 SSTYRLESTLNYGMERVWCVA-SLRGSNNVALGYDEGSIIV 297
Score = 56.8 bits (131), Expect = 5e-07
Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 3/132 (2%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGG-KLSQVLVGHSDIVTCVAVSITNKT 1190
+H++ I C A+ ++T S DM +K+W D SQV GH+ V + ++ +
Sbjct: 97 AHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNN 156
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV--TGDGTIAVSCAEDKTLIIWET 1248
Q S S D + VW + + V C+ GD +S A+D+ + IW+
Sbjct: 157 QFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDY 216
Query: 1249 KRGLALTSFSLH 1260
+ + + H
Sbjct: 217 QNKTCVQTLEGH 228
Score = 55.6 bits (128), Expect = 1e-06
Identities = 36/134 (26%), Positives = 65/134 (48%), Gaps = 3/134 (2%)
Query: 690 FKGHSGSILCMCVT-RESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIV-- 746
F+GH+ ++ + + +++ + S D ++ VW L + + + H V C+
Sbjct: 138 FEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGG 197
Query: 747 NRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
++ +ISG DD V I + V L+ H +V+ + I ITGS+DGTV W+
Sbjct: 198 DKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWH 257
Query: 807 VENFTLLSTVTAGV 820
+ L ST+ G+
Sbjct: 258 SSTYRLESTLNYGM 271
Score = 52.8 bits (121), Expect = 9e-06
Identities = 42/180 (23%), Positives = 81/180 (45%), Gaps = 12/180 (6%)
Query: 989 LVRVWQLSTH-RLQATLNGHIGHITCVTFSP-NNLLVLSGSEDRTVVVWQLADNSPSLTY 1046
L+++W GH ++ + +P +N S S DRT+ VWQL +SP+ T
Sbjct: 122 LIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTL 181
Query: 1047 KGHSSAIQTLLMMSDGRR--AMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKY 1103
+GH + + S G + +S R V +W + + + G + ++ + + +
Sbjct: 182 EGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPEL 241
Query: 1104 AVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHA-ERITCFALTADSQHVVTGSMDMSLKV 1160
++ G D +VRIW ++ ++++ ER+ C A S +V G + S+ V
Sbjct: 242 PIIITGSEDGTVRIWH----SSTYRLESTLNYGMERVWCVASLRGSNNVALGYDEGSIIV 297
Score = 50.8 bits (116), Expect = 4e-05
Identities = 23/86 (26%), Positives = 47/86 (54%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + + V T +GH+ ++ C E ++TGSED +V +W T +++ + +
Sbjct: 212 KIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGM 271
Query: 737 APVLCVAAIVNRSLVISGGDDSAVII 762
V CVA++ + V G D+ ++I+
Sbjct: 272 ERVWCVASLRGSNNVALGYDEGSIIV 297
Score = 49.2 bits (112), Expect = 1e-04
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
Query: 1145 DSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAV-SITNKTQVVSGSWDCNLIV 1203
D+ + S+D ++KVW+L + L GH V C+ S +K ++SG+ D + +
Sbjct: 154 DNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKI 213
Query: 1204 WDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWET 1248
WD V+C + I ++ +ED T+ IW +
Sbjct: 214 WDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHS 258
Score = 48.4 bits (110), Expect = 2e-04
Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 6/86 (6%)
Query: 952 STTNITLLQAEQSDLIPISCLEVSRDGQLG--ASGCARGLVRVWQLSTHRLQATLNGHIG 1009
S+ N TL E+ ++C++ G SG LV++W TL GH
Sbjct: 175 SSPNFTLEGHEKG----VNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQ 230
Query: 1010 HITCVTFSPNNLLVLSGSEDRTVVVW 1035
+++C +F P ++++GSED TV +W
Sbjct: 231 NVSCASFHPELPIIITGSEDGTVRIW 256
Score = 47.2 bits (107), Expect = 4e-04
Identities = 45/200 (22%), Positives = 85/200 (42%), Gaps = 7/200 (3%)
Query: 686 KVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE-HIAPVL-CVA 743
+VH F+ HS I C+ V ++LT S+D + +WD +++ E H V+ V
Sbjct: 91 RVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVI 150
Query: 744 AIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN--IFITGSQDGT 801
+ + S D + + L + L+ H V + G+ I+G+ D
Sbjct: 151 NPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRL 210
Query: 802 VCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHK 861
V W+ +N T + T+ G ++ + + + G + +R + + TY +
Sbjct: 211 VKIWDYQNKTCVQTL-EGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNY 269
Query: 862 AKVKCFCVA--HDSSRVAVG 879
+ +CVA S+ VA+G
Sbjct: 270 GMERVWCVASLRGSNNVALG 289
Score = 47.2 bits (107), Expect = 4e-04
Identities = 29/128 (22%), Positives = 56/128 (43%), Gaps = 2/128 (1%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTR--ESQYLLTGSEDTSVIVWDLHTLAVKTKILE 734
++W + S+S T +GH + C+ + YL++G++D V +WD +
Sbjct: 168 KVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEG 227
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H V C + ++I+G +D V I L + L++ V V ++ N
Sbjct: 228 HAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLRGSNNVA 287
Query: 795 TGSQDGTV 802
G +G++
Sbjct: 288 LGYDEGSI 295
Score = 44.0 bits (99), Expect = 0.004
Identities = 23/104 (22%), Positives = 45/104 (43%), Gaps = 2/104 (1%)
Query: 976 RDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTF--SPNNLLVLSGSEDRTVV 1033
+D AS ++VWQL + TL GH + C+ + + ++SG++DR V
Sbjct: 153 KDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVK 212
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
+W + + T +GH+ + + ++ V +W
Sbjct: 213 IWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
Score = 43.2 bits (97), Expect = 0.007
Identities = 25/99 (25%), Positives = 48/99 (48%), Gaps = 1/99 (1%)
Query: 955 NITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCV 1014
N T +Q + +SC + + +G G VR+W ST+RL++TLN + + CV
Sbjct: 218 NKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCV 277
Query: 1015 TFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
+ V G ++ +++V +L P+++ + I
Sbjct: 278 ASLRGSNNVALGYDEGSIIV-KLGREEPAMSMDANGKII 315
Score = 41.5 bits (93), Expect = 0.021
Identities = 45/247 (18%), Positives = 99/247 (40%), Gaps = 7/247 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ L P+ ++ + G +W+ + + V TF+ + +++TG++D
Sbjct: 21 VDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQ 80
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL-DH 776
+ V++ +TL H + C+A + +++ DD + + +++ +
Sbjct: 81 IRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEG 140
Query: 777 HRGSVTSVKV-IQDGNIFITGSQDGTVCTWNV----ENFTLLSTVTAGVPIHIFDVTDDN 831
H V + + +D N F + S D T+ W + NFT L GV + D
Sbjct: 141 HTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFT-LEGHEKGVNCIDYYSGGDK 199
Query: 832 VFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLH 891
+L++ D + + + T + L+ H V C + + G D + ++
Sbjct: 200 PYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSS 259
Query: 892 SAQLLRT 898
+ +L T
Sbjct: 260 TYRLEST 266
Score = 35.1 bits (77), Expect = 1.9
Identities = 18/57 (31%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Query: 1149 VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
VVTG+ DM ++V+ + + + HSD + C+AV T + +++ S D + +WD
Sbjct: 72 VVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPT-QPFILTSSDDMLIKLWD 127
Score = 34.7 bits (76), Expect = 2.5
Identities = 25/117 (21%), Positives = 45/117 (38%), Gaps = 1/117 (0%)
Query: 773 KLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV-TAGVPIHIFDVTDDN 831
KL V SV + + +G+VC WN E TL+ T +P+
Sbjct: 10 KLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARK 69
Query: 832 VFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
+++T D ++ + + T +H + H ++C V + D I L+
Sbjct: 70 NWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLW 126
>BC001648-1|AAH01648.1| 432|Homo sapiens WD repeat domain 18 protein.
Length = 432
Score = 62.9 bits (146), Expect = 8e-09
Identities = 54/216 (25%), Positives = 103/216 (47%), Gaps = 23/216 (10%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
P++CL S +G +G A + +W++ST L L+ H ++C+ F+ ++ +SG
Sbjct: 82 PVTCLTASPNGLYVLAGVAES-IHLWEVSTGNLLVILSRHYQDVSCLQFTGDSSHFISGG 140
Query: 1028 EDRTVVVWQL-----ADNS----PSLTYKGHSSAIQTLLMMSDG--RRAMSSDRARNVHV 1076
+D V+VW L AD S P + H+ I L G R +S + V +
Sbjct: 141 KDCLVLVWSLCSVLQADPSRIPAPRHVWSHHTLPITDLHCGFGGPLARVATSSLDQTVKL 200
Query: 1077 WLVDSGIVLHSATGPSASIDVTLNM-KYAVLSDGDN----SVRIWSLAG----GDNSEDN 1127
W V SG +L S + + VT+++ ++ + G V +++ G + E +
Sbjct: 201 WEVSSGELLLSVLFDVSIMAVTMDLAEHHMFCGGSEGSIFQVDLFTWPGQRERSFHPEQD 260
Query: 1128 RRSV--SHAERITCFALTADSQHVVTGSMDMSLKVW 1161
V H ++TC +++ D +++GS D ++++W
Sbjct: 261 AGKVFKGHRNQVTCLSVSTDGSVLLSGSHDETVRLW 296
Score = 53.2 bits (122), Expect = 7e-06
Identities = 64/261 (24%), Positives = 110/261 (42%), Gaps = 27/261 (10%)
Query: 663 SGQHLVLAPSAGDPQL--WHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+G++L LA G + W + ++ G + C+ + Y+L G + S+ +
Sbjct: 48 NGEYL-LAAQLGKNYISAWELQRKDQLQQKIMCPGPVTCLTASPNGLYVLAGVAE-SIHL 105
Query: 721 WDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-----VDGALVTK-- 773
W++ T + + H V C+ + S ISGG D V++ SL D + +
Sbjct: 106 WEVSTGNLLVILSRHYQDVSCLQFTGDSSHFISGGKDCLVLVWSLCSVLQADPSRIPAPR 165
Query: 774 --LDHHRGSVTSVKVIQDGNI--FITGSQDGTVCTWNVENFTLLSTVTAGVPIHI--FDV 827
HH +T + G + T S D TV W V + LL +V V I D+
Sbjct: 166 HVWSHHTLPITDLHCGFGGPLARVATSSLDQTVKLWEVSSGELLLSVLFDVSIMAVTMDL 225
Query: 828 TDDNVFLLTLQGDN-ELHLRTFI--TGTYLHP-------LKRHKAKVKCFCVAHDSSRVA 877
+ ++F +G ++ L T+ HP K H+ +V C V+ D S +
Sbjct: 226 AEHHMFCGGSEGSIFQVDLFTWPGQRERSFHPEQDAGKVFKGHRNQVTCLSVSTDGSVLL 285
Query: 878 VGCADQRIYLYSLHSAQLLRT 898
G D+ + L+ + S Q +RT
Sbjct: 286 SGSHDETVRLWDVQSKQCIRT 306
Score = 48.4 bits (110), Expect = 2e-04
Identities = 33/135 (24%), Positives = 62/135 (45%), Gaps = 9/135 (6%)
Query: 1033 VVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARN-VHVWLVDSGIVLHS---A 1088
+VW+L + LTY+G + + L +++ G +++ +N + W + L
Sbjct: 21 IVWELHSGANLLTYRGGQAGPRGLALLN-GEYLLAAQLGKNYISAWELQRKDQLQQKIMC 79
Query: 1089 TGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQH 1148
GP + + N Y VL+ S+ +W ++ G+ R H + ++C T DS H
Sbjct: 80 PGPVTCLTASPNGLY-VLAGVAESIHLWEVSTGNLLVILSR---HYQDVSCLQFTGDSSH 135
Query: 1149 VVTGSMDMSLKVWKL 1163
++G D + VW L
Sbjct: 136 FISGGKDCLVLVWSL 150
Score = 46.4 bits (105), Expect = 8e-04
Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 8/134 (5%)
Query: 1076 VWLVDSGIVLHSATGPSASID--VTLNMKYAVLSD-GDNSVRIWSLAGGDNSEDNRRSVS 1132
VW + SG L + G A LN +Y + + G N + W L D + + +
Sbjct: 22 VWELHSGANLLTYRGGQAGPRGLALLNGEYLLAAQLGKNYISAWELQRKDQLQ---QKIM 78
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC + + +V+ G + S+ +W++ G L +L H V+C+ + + +
Sbjct: 79 CPGPVTCLTASPNGLYVLAGVAE-SIHLWEVSTGNLLVILSRHYQDVSCLQFT-GDSSHF 136
Query: 1193 VSGSWDCNLIVWDI 1206
+SG DC ++VW +
Sbjct: 137 ISGGKDCLVLVWSL 150
Score = 44.0 bits (99), Expect = 0.004
Identities = 58/257 (22%), Positives = 110/257 (42%), Gaps = 40/257 (15%)
Query: 982 ASGCARGLVRVWQLSTH-RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN 1040
A+ + + W+L +LQ + G +TC+T SPN L VL+G + ++ +W+++
Sbjct: 54 AAQLGKNYISAWELQRKDQLQQKIMCP-GPVTCLTASPNGLYVLAGVAE-SIHLWEVSTG 111
Query: 1041 SPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA------- 1093
+ + H + L D +S + V VW + S + + P+
Sbjct: 112 NLLVILSRHYQDVSCLQFTGDSSHFISGGKDCLVLVWSLCSVLQADPSRIPAPRHVWSHH 171
Query: 1094 SIDVT-LNMKY------AVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
++ +T L+ + S D +V++W ++ G + SV I +
Sbjct: 172 TLPITDLHCGFGGPLARVATSSLDQTVKLWEVSSG----ELLLSVLFDVSIMAVTMDLAE 227
Query: 1147 QHVVTGSMD-----MSLKVW----------KLDGGKLSQVLVGHSDIVTCVAVSITNKTQ 1191
H+ G + + L W + D GK V GH + VTC++VS T+ +
Sbjct: 228 HHMFCGGSEGSIFQVDLFTWPGQRERSFHPEQDAGK---VFKGHRNQVTCLSVS-TDGSV 283
Query: 1192 VVSGSWDCNLIVWDINT 1208
++SGS D + +WD+ +
Sbjct: 284 LLSGSHDETVRLWDVQS 300
Score = 41.5 bits (93), Expect = 0.021
Identities = 44/215 (20%), Positives = 89/215 (41%), Gaps = 23/215 (10%)
Query: 1071 ARNVHVWLVDSG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDN 1127
A ++H+W V +G ++L + + T + + + D V +WSL ++ +
Sbjct: 100 AESIHLWEVSTGNLLVILSRHYQDVSCLQFTGDSSHFISGGKDCLVLVWSLCSVLQADPS 159
Query: 1128 R----RSV--SHAERITCF--ALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV 1179
R R V H IT V T S+D ++K+W++ G+L ++ I+
Sbjct: 160 RIPAPRHVWSHHTLPITDLHCGFGGPLARVATSSLDQTVKLWEVSSGELLLSVLFDVSIM 219
Query: 1180 TCVAVSITNKTQVVSGS----WDCNLIVWDINTXXXXXXXXXXXX-------KVTCVKVT 1228
V + + GS + +L W +VTC+ V+
Sbjct: 220 A-VTMDLAEHHMFCGGSEGSIFQVDLFTWPGQRERSFHPEQDAGKVFKGHRNQVTCLSVS 278
Query: 1229 GDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPL 1263
DG++ +S + D+T+ +W+ + + + +L P+
Sbjct: 279 TDGSVLLSGSHDETVRLWDVQSKQCIRTVALKGPV 313
Score = 39.9 bits (89), Expect = 0.066
Identities = 17/46 (36%), Positives = 27/46 (58%)
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPI 822
HR VT + V DG++ ++GS D TV W+V++ + TV P+
Sbjct: 268 HRNQVTCLSVSTDGSVLLSGSHDETVRLWDVQSKQCIRTVALKGPV 313
Score = 38.7 bits (86), Expect = 0.15
Identities = 19/66 (28%), Positives = 34/66 (51%), Gaps = 1/66 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L +P+G + VLA A LW + + + + H + C+ T +S + ++G +D
Sbjct: 86 LTASPNGLY-VLAGVAESIHLWEVSTGNLLVILSRHYQDVSCLQFTGDSSHFISGGKDCL 144
Query: 718 VIVWDL 723
V+VW L
Sbjct: 145 VLVWSL 150
Score = 34.7 bits (76), Expect = 2.5
Identities = 20/89 (22%), Positives = 42/89 (47%), Gaps = 2/89 (2%)
Query: 1158 LKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXX 1217
+ W+L Q + VTC+ S N V++G + ++ +W+++T
Sbjct: 62 ISAWELQRKDQLQQKIMCPGPVTCLTAS-PNGLYVLAGVAE-SIHLWEVSTGNLLVILSR 119
Query: 1218 XXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
V+C++ TGD + +S +D +++W
Sbjct: 120 HYQDVSCLQFTGDSSHFISGGKDCLVLVW 148
>BC000326-1|AAH00326.1| 906|Homo sapiens coatomer protein complex,
subunit beta 2 (beta prime) protein.
Length = 906
Score = 62.9 bits (146), Expect = 8e-09
Identities = 48/221 (21%), Positives = 92/221 (41%), Gaps = 11/221 (4%)
Query: 990 VRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN-SPSLTYKG 1048
+RV+ +T H +I C+ P +L+ S+D + +W S S ++G
Sbjct: 81 IRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEG 140
Query: 1049 HSSAI-QTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASIDVTL-----NMK 1102
H+ + Q ++ D + S+ R + VW + S + G ++ +
Sbjct: 141 HTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKP 200
Query: 1103 YAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQHVVTGSMDMSLKVWK 1162
Y + D V+IW N + HA+ ++C + + ++TGS D ++++W
Sbjct: 201 YLISGADDRLVKIWDY---QNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWH 257
Query: 1163 LDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIV 1203
+L L + V CVA S+ V G + ++IV
Sbjct: 258 SSTYRLESTLNYGMERVWCVA-SLRGSNNVALGYDEGSIIV 297
Score = 56.8 bits (131), Expect = 5e-07
Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 3/132 (2%)
Query: 1132 SHAERITCFALTADSQHVVTGSMDMSLKVWKLDGG-KLSQVLVGHSDIVTCVAVSITNKT 1190
+H++ I C A+ ++T S DM +K+W D SQV GH+ V + ++ +
Sbjct: 97 AHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNN 156
Query: 1191 QVVSGSWDCNLIVWDINTXXXXXXXXXXXXKVTCVKV--TGDGTIAVSCAEDKTLIIWET 1248
Q S S D + VW + + V C+ GD +S A+D+ + IW+
Sbjct: 157 QFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDY 216
Query: 1249 KRGLALTSFSLH 1260
+ + + H
Sbjct: 217 QNKTCVQTLEGH 228
Score = 55.6 bits (128), Expect = 1e-06
Identities = 36/134 (26%), Positives = 65/134 (48%), Gaps = 3/134 (2%)
Query: 690 FKGHSGSILCMCVT-RESQYLLTGSEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIV-- 746
F+GH+ ++ + + +++ + S D ++ VW L + + + H V C+
Sbjct: 138 FEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGG 197
Query: 747 NRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
++ +ISG DD V I + V L+ H +V+ + I ITGS+DGTV W+
Sbjct: 198 DKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWH 257
Query: 807 VENFTLLSTVTAGV 820
+ L ST+ G+
Sbjct: 258 SSTYRLESTLNYGM 271
Score = 52.8 bits (121), Expect = 9e-06
Identities = 42/180 (23%), Positives = 81/180 (45%), Gaps = 12/180 (6%)
Query: 989 LVRVWQLSTH-RLQATLNGHIGHITCVTFSP-NNLLVLSGSEDRTVVVWQLADNSPSLTY 1046
L+++W GH ++ + +P +N S S DRT+ VWQL +SP+ T
Sbjct: 122 LIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTL 181
Query: 1047 KGHSSAIQTLLMMSDGRR--AMSSDRARNVHVWLVDSGIVLHSATGPSASID-VTLNMKY 1103
+GH + + S G + +S R V +W + + + G + ++ + + +
Sbjct: 182 EGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPEL 241
Query: 1104 AVLSDG--DNSVRIWSLAGGDNSEDNRRSVSHA-ERITCFALTADSQHVVTGSMDMSLKV 1160
++ G D +VRIW ++ ++++ ER+ C A S +V G + S+ V
Sbjct: 242 PIIITGSEDGTVRIWH----SSTYRLESTLNYGMERVWCVASLRGSNNVALGYDEGSIIV 297
Score = 50.8 bits (116), Expect = 4e-05
Identities = 23/86 (26%), Positives = 47/86 (54%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILEHI 736
++W + + V T +GH+ ++ C E ++TGSED +V +W T +++ + +
Sbjct: 212 KIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGM 271
Query: 737 APVLCVAAIVNRSLVISGGDDSAVII 762
V CVA++ + V G D+ ++I+
Sbjct: 272 ERVWCVASLRGSNNVALGYDEGSIIV 297
Score = 49.2 bits (112), Expect = 1e-04
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
Query: 1145 DSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAV-SITNKTQVVSGSWDCNLIV 1203
D+ + S+D ++KVW+L + L GH V C+ S +K ++SG+ D + +
Sbjct: 154 DNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKI 213
Query: 1204 WDINTXXXXXXXXXXXXKVTCVKVTGDGTIAVSCAEDKTLIIWET 1248
WD V+C + I ++ +ED T+ IW +
Sbjct: 214 WDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHS 258
Score = 48.4 bits (110), Expect = 2e-04
Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 6/86 (6%)
Query: 952 STTNITLLQAEQSDLIPISCLEVSRDGQLG--ASGCARGLVRVWQLSTHRLQATLNGHIG 1009
S+ N TL E+ ++C++ G SG LV++W TL GH
Sbjct: 175 SSPNFTLEGHEKG----VNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQ 230
Query: 1010 HITCVTFSPNNLLVLSGSEDRTVVVW 1035
+++C +F P ++++GSED TV +W
Sbjct: 231 NVSCASFHPELPIIITGSEDGTVRIW 256
Score = 47.2 bits (107), Expect = 4e-04
Identities = 45/200 (22%), Positives = 85/200 (42%), Gaps = 7/200 (3%)
Query: 686 KVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIVWDLHTLAVKTKILE-HIAPVL-CVA 743
+VH F+ HS I C+ V ++LT S+D + +WD +++ E H V+ V
Sbjct: 91 RVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVI 150
Query: 744 AIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGN--IFITGSQDGT 801
+ + S D + + L + L+ H V + G+ I+G+ D
Sbjct: 151 NPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRL 210
Query: 802 VCTWNVENFTLLSTVTAGVPIHIFDVTDDNVFLLTLQGDNELHLRTFITGTYLHPLKRHK 861
V W+ +N T + T+ G ++ + + + G + +R + + TY +
Sbjct: 211 VKIWDYQNKTCVQTL-EGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNY 269
Query: 862 AKVKCFCVA--HDSSRVAVG 879
+ +CVA S+ VA+G
Sbjct: 270 GMERVWCVASLRGSNNVALG 289
Score = 47.2 bits (107), Expect = 4e-04
Identities = 29/128 (22%), Positives = 56/128 (43%), Gaps = 2/128 (1%)
Query: 677 QLWHIMSNSKVHTFKGHSGSILCMCVTR--ESQYLLTGSEDTSVIVWDLHTLAVKTKILE 734
++W + S+S T +GH + C+ + YL++G++D V +WD +
Sbjct: 168 KVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEG 227
Query: 735 HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHHRGSVTSVKVIQDGNIFI 794
H V C + ++I+G +D V I L + L++ V V ++ N
Sbjct: 228 HAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLRGSNNVA 287
Query: 795 TGSQDGTV 802
G +G++
Sbjct: 288 LGYDEGSI 295
Score = 44.0 bits (99), Expect = 0.004
Identities = 23/104 (22%), Positives = 45/104 (43%), Gaps = 2/104 (1%)
Query: 976 RDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTF--SPNNLLVLSGSEDRTVV 1033
+D AS ++VWQL + TL GH + C+ + + ++SG++DR V
Sbjct: 153 KDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVK 212
Query: 1034 VWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVW 1077
+W + + T +GH+ + + ++ V +W
Sbjct: 213 IWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
Score = 43.2 bits (97), Expect = 0.007
Identities = 25/99 (25%), Positives = 48/99 (48%), Gaps = 1/99 (1%)
Query: 955 NITLLQAEQSDLIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCV 1014
N T +Q + +SC + + +G G VR+W ST+RL++TLN + + CV
Sbjct: 218 NKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCV 277
Query: 1015 TFSPNNLLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAI 1053
+ V G ++ +++V +L P+++ + I
Sbjct: 278 ASLRGSNNVALGYDEGSIIV-KLGREEPAMSMDANGKII 315
Score = 41.5 bits (93), Expect = 0.021
Identities = 45/247 (18%), Positives = 99/247 (40%), Gaps = 7/247 (2%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
+ L P+ ++ + G +W+ + + V TF+ + +++TG++D
Sbjct: 21 VDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQ 80
Query: 718 VIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKL-DH 776
+ V++ +TL H + C+A + +++ DD + + +++ +
Sbjct: 81 IRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEG 140
Query: 777 HRGSVTSVKV-IQDGNIFITGSQDGTVCTWNV----ENFTLLSTVTAGVPIHIFDVTDDN 831
H V + + +D N F + S D T+ W + NFT L GV + D
Sbjct: 141 HTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFT-LEGHEKGVNCIDYYSGGDK 199
Query: 832 VFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLH 891
+L++ D + + + T + L+ H V C + + G D + ++
Sbjct: 200 PYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSS 259
Query: 892 SAQLLRT 898
+ +L T
Sbjct: 260 TYRLEST 266
Score = 35.1 bits (77), Expect = 1.9
Identities = 18/57 (31%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Query: 1149 VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWD 1205
VVTG+ DM ++V+ + + + HSD + C+AV T + +++ S D + +WD
Sbjct: 72 VVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPT-QPFILTSSDDMLIKLWD 127
Score = 34.7 bits (76), Expect = 2.5
Identities = 25/117 (21%), Positives = 45/117 (38%), Gaps = 1/117 (0%)
Query: 773 KLDHHRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTV-TAGVPIHIFDVTDDN 831
KL V SV + + +G+VC WN E TL+ T +P+
Sbjct: 10 KLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARK 69
Query: 832 VFLLTLQGDNELHLRTFITGTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLY 888
+++T D ++ + + T +H + H ++C V + D I L+
Sbjct: 70 NWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLW 126
>BC000040-1|AAH00040.2| 432|Homo sapiens WD repeat domain 18 protein.
Length = 432
Score = 62.9 bits (146), Expect = 8e-09
Identities = 54/216 (25%), Positives = 103/216 (47%), Gaps = 23/216 (10%)
Query: 968 PISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGS 1027
P++CL S +G +G A + +W++ST L L+ H ++C+ F+ ++ +SG
Sbjct: 82 PVTCLTASPNGLYVLAGVAES-IHLWEVSTGNLLVILSRHYQDVSCLQFTGDSSHFISGG 140
Query: 1028 EDRTVVVWQL-----ADNS----PSLTYKGHSSAIQTLLMMSDG--RRAMSSDRARNVHV 1076
+D V+VW L AD S P + H+ I L G R +S + V +
Sbjct: 141 KDCLVLVWSLCSVLQADPSRIPAPRHVWSHHTLPITDLHCGFGGPLARVATSSLDQTVKL 200
Query: 1077 WLVDSGIVLHSATGPSASIDVTLNM-KYAVLSDGDN----SVRIWSLAG----GDNSEDN 1127
W V SG +L S + + VT+++ ++ + G V +++ G + E +
Sbjct: 201 WEVSSGELLLSVLFDVSIMAVTMDLAEHHMFCGGSEGSIFQVDLFTWPGQRERSFHPEQD 260
Query: 1128 RRSV--SHAERITCFALTADSQHVVTGSMDMSLKVW 1161
V H ++TC +++ D +++GS D ++++W
Sbjct: 261 AGKVFKGHRNQVTCLSVSTDGSVLLSGSHDETVRLW 296
Score = 53.2 bits (122), Expect = 7e-06
Identities = 64/261 (24%), Positives = 110/261 (42%), Gaps = 27/261 (10%)
Query: 663 SGQHLVLAPSAGDPQL--WHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTSVIV 720
+G++L LA G + W + ++ G + C+ + Y+L G + S+ +
Sbjct: 48 NGEYL-LAAQLGKNYISAWELQRKDQLQQKIMCPGPVTCLTASPNGLYVLAGVAE-SIHL 105
Query: 721 WDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSL-----VDGALVTK-- 773
W++ T + + H V C+ + S ISGG D V++ SL D + +
Sbjct: 106 WEVSTGNLLVILSRHYQDVSCLQFTGDSSHFISGGKDCLVLVWSLCSVLQADPSRIPAPR 165
Query: 774 --LDHHRGSVTSVKVIQDGNI--FITGSQDGTVCTWNVENFTLLSTVTAGVPIHI--FDV 827
HH +T + G + T S D TV W V + LL +V V I D+
Sbjct: 166 HVWSHHTLPITDLHCGFGGPLARVATSSLDQTVKLWEVSSGELLLSVLFDVSIMAVTMDL 225
Query: 828 TDDNVFLLTLQGDN-ELHLRTFI--TGTYLHP-------LKRHKAKVKCFCVAHDSSRVA 877
+ ++F +G ++ L T+ HP K H+ +V C V+ D S +
Sbjct: 226 AEHHMFCGGSEGSIFQVDLFTWPGQRERSFHPEQDAGKVFKGHRNQVTCLSVSTDGSVLL 285
Query: 878 VGCADQRIYLYSLHSAQLLRT 898
G D+ + L+ + S Q +RT
Sbjct: 286 SGSHDETVRLWDVQSKQCIRT 306
Score = 48.4 bits (110), Expect = 2e-04
Identities = 33/135 (24%), Positives = 62/135 (45%), Gaps = 9/135 (6%)
Query: 1033 VVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARN-VHVWLVDSGIVLHS---A 1088
+VW+L + LTY+G + + L +++ G +++ +N + W + L
Sbjct: 21 IVWELHSGANLLTYRGGQAGPRGLALLN-GEYLLAAQLGKNYISAWELQRKDQLQQKIMC 79
Query: 1089 TGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADSQH 1148
GP + + N Y VL+ S+ +W ++ G+ R H + ++C T DS H
Sbjct: 80 PGPVTCLTASPNGLY-VLAGVAESIHLWEVSTGNLLVILSR---HYQDVSCLQFTGDSSH 135
Query: 1149 VVTGSMDMSLKVWKL 1163
++G D + VW L
Sbjct: 136 FISGGKDCLVLVWSL 150
Score = 46.4 bits (105), Expect = 8e-04
Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 8/134 (5%)
Query: 1076 VWLVDSGIVLHSATGPSASID--VTLNMKYAVLSD-GDNSVRIWSLAGGDNSEDNRRSVS 1132
VW + SG L + G A LN +Y + + G N + W L D + + +
Sbjct: 22 VWELHSGANLLTYRGGQAGPRGLALLNGEYLLAAQLGKNYISAWELQRKDQLQ---QKIM 78
Query: 1133 HAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQV 1192
+TC + + +V+ G + S+ +W++ G L +L H V+C+ + + +
Sbjct: 79 CPGPVTCLTASPNGLYVLAGVAE-SIHLWEVSTGNLLVILSRHYQDVSCLQFT-GDSSHF 136
Query: 1193 VSGSWDCNLIVWDI 1206
+SG DC ++VW +
Sbjct: 137 ISGGKDCLVLVWSL 150
Score = 44.0 bits (99), Expect = 0.004
Identities = 58/257 (22%), Positives = 110/257 (42%), Gaps = 40/257 (15%)
Query: 982 ASGCARGLVRVWQLSTH-RLQATLNGHIGHITCVTFSPNNLLVLSGSEDRTVVVWQLADN 1040
A+ + + W+L +LQ + G +TC+T SPN L VL+G + ++ +W+++
Sbjct: 54 AAQLGKNYISAWELQRKDQLQQKIMCP-GPVTCLTASPNGLYVLAGVAE-SIHLWEVSTG 111
Query: 1041 SPSLTYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSA------- 1093
+ + H + L D +S + V VW + S + + P+
Sbjct: 112 NLLVILSRHYQDVSCLQFTGDSSHFISGGKDCLVLVWSLCSVLQADPSRIPAPRHVWSHH 171
Query: 1094 SIDVT-LNMKY------AVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAERITCFALTADS 1146
++ +T L+ + S D +V++W ++ G + SV I +
Sbjct: 172 TLPITDLHCGFGGPLARVATSSLDQTVKLWEVSSG----ELLLSVLFDVSIMAVTMDLAE 227
Query: 1147 QHVVTGSMD-----MSLKVW----------KLDGGKLSQVLVGHSDIVTCVAVSITNKTQ 1191
H+ G + + L W + D GK V GH + VTC++VS T+ +
Sbjct: 228 HHMFCGGSEGSIFQVDLFTWPGQRERSFHPEQDAGK---VFKGHRNQVTCLSVS-TDGSV 283
Query: 1192 VVSGSWDCNLIVWDINT 1208
++SGS D + +WD+ +
Sbjct: 284 LLSGSHDETVRLWDVQS 300
Score = 41.5 bits (93), Expect = 0.021
Identities = 44/215 (20%), Positives = 89/215 (41%), Gaps = 23/215 (10%)
Query: 1071 ARNVHVWLVDSG---IVLHSATGPSASIDVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDN 1127
A ++H+W V +G ++L + + T + + + D V +WSL ++ +
Sbjct: 100 AESIHLWEVSTGNLLVILSRHYQDVSCLQFTGDSSHFISGGKDCLVLVWSLCSVLQADPS 159
Query: 1128 R----RSV--SHAERITCF--ALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGHSDIV 1179
R R V H IT V T S+D ++K+W++ G+L ++ I+
Sbjct: 160 RIPAPRHVWSHHTLPITDLHCGFGGPLARVATSSLDQTVKLWEVSSGELLLSVLFDVSIM 219
Query: 1180 TCVAVSITNKTQVVSGS----WDCNLIVWDINTXXXXXXXXXXXX-------KVTCVKVT 1228
V + + GS + +L W +VTC+ V+
Sbjct: 220 A-VTMDLAEHHMFCGGSEGSIFQVDLFTWPGQRERSFHPEQDAGKVFKGHRNQVTCLSVS 278
Query: 1229 GDGTIAVSCAEDKTLIIWETKRGLALTSFSLHVPL 1263
DG++ +S + D+T+ +W+ + + + +L P+
Sbjct: 279 TDGSVLLSGSHDETVRLWDVQSKQCIRTVALKGPV 313
Score = 39.9 bits (89), Expect = 0.066
Identities = 17/46 (36%), Positives = 27/46 (58%)
Query: 777 HRGSVTSVKVIQDGNIFITGSQDGTVCTWNVENFTLLSTVTAGVPI 822
HR VT + V DG++ ++GS D TV W+V++ + TV P+
Sbjct: 268 HRNQVTCLSVSTDGSVLLSGSHDETVRLWDVQSKQCIRTVALKGPV 313
Score = 38.7 bits (86), Expect = 0.15
Identities = 19/66 (28%), Positives = 34/66 (51%), Gaps = 1/66 (1%)
Query: 658 LQLAPSGQHLVLAPSAGDPQLWHIMSNSKVHTFKGHSGSILCMCVTRESQYLLTGSEDTS 717
L +P+G + VLA A LW + + + + H + C+ T +S + ++G +D
Sbjct: 86 LTASPNGLY-VLAGVAESIHLWEVSTGNLLVILSRHYQDVSCLQFTGDSSHFISGGKDCL 144
Query: 718 VIVWDL 723
V+VW L
Sbjct: 145 VLVWSL 150
Score = 34.7 bits (76), Expect = 2.5
Identities = 20/89 (22%), Positives = 42/89 (47%), Gaps = 2/89 (2%)
Query: 1158 LKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINTXXXXXXXXX 1217
+ W+L Q + VTC+ S N V++G + ++ +W+++T
Sbjct: 62 ISAWELQRKDQLQQKIMCPGPVTCLTAS-PNGLYVLAGVAE-SIHLWEVSTGNLLVILSR 119
Query: 1218 XXXKVTCVKVTGDGTIAVSCAEDKTLIIW 1246
V+C++ TGD + +S +D +++W
Sbjct: 120 HYQDVSCLQFTGDSSHFISGGKDCLVLVW 148
>BC015887-1|AAH15887.1| 404|Homo sapiens WD repeat and SOCS
box-containing 2 protein.
Length = 404
Score = 62.5 bits (145), Expect = 1e-08
Identities = 39/149 (26%), Positives = 69/149 (46%), Gaps = 4/149 (2%)
Query: 662 PSGQHLVLAPSAGDPQL--WHIMSNSKVHTFKGHSGSILCMCVTRE-SQYLLTGSEDTSV 718
P LVLA D Q+ W + + + GH + + T S L++ S D ++
Sbjct: 119 PDVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTL 178
Query: 719 IVWDLHTLAVKTKILE-HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+WDL+ + ++L H+ V C + + S++ S + +V + S+ L+ KL+ H
Sbjct: 179 RIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGH 238
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
+ SV S D + +T S D V W+
Sbjct: 239 QSSVVSCDFSPDSALLVTASYDTNVIMWD 267
Score = 55.2 bits (127), Expect = 2e-06
Identities = 40/197 (20%), Positives = 87/197 (44%), Gaps = 14/197 (7%)
Query: 982 ASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPN-NLLVLSGSEDRTVVVWQLADN 1040
A+G G +++W++ T L L+GH + ++F+P+ +L+++S S D+T+ +W L +
Sbjct: 127 ATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKH 186
Query: 1041 SPSL-TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI---D 1096
+ GH + + D S+ ++V +W + S ++ G +S+ D
Sbjct: 187 GKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCD 246
Query: 1097 VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRR---------SVSHAERITCFALTADSQ 1147
+ + V + D +V +W G+ S H + + +
Sbjct: 247 FSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPEGL 306
Query: 1148 HVVTGSMDMSLKVWKLD 1164
++ T + D L++W L+
Sbjct: 307 YLATVADDRLLRIWALE 323
Score = 51.6 bits (118), Expect = 2e-05
Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
Query: 1149 VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINT 1208
+ TG D +K+W++ G L L GH D+V ++ + + +VS S D L +WD+N
Sbjct: 126 LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNK 185
Query: 1209 XXXXXXXXXXXXK-VTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
+ V C ++ D ++ S A +K++ +W +
Sbjct: 186 HGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMR 227
Score = 46.0 bits (104), Expect = 0.001
Identities = 30/137 (21%), Positives = 70/137 (51%), Gaps = 9/137 (6%)
Query: 1074 VHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVL---SDGDNSVRIWSLAGGDNSEDNRR 1129
+ +W V +G++L + +G + D++ +++ + D ++RIW L + + +
Sbjct: 135 IKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDL--NKHGKQIQV 192
Query: 1130 SVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGH-SDIVTCVAVSITN 1188
H + + C +++ D + + + + S+ +W + L + L GH S +V+C +
Sbjct: 193 LSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSC--DFSPD 250
Query: 1189 KTQVVSGSWDCNLIVWD 1205
+V+ S+D N+I+WD
Sbjct: 251 SALLVTASYDTNVIMWD 267
Score = 42.3 bits (95), Expect = 0.012
Identities = 28/124 (22%), Positives = 56/124 (45%), Gaps = 4/124 (3%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQL--WHIMSNSK-VHTFKGHSGSILCMCVTRESQYLLTG 712
R L PSG L+L ++ D L W + + K + GH + C ++ + L +
Sbjct: 157 RDLSFTPSGS-LILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSA 215
Query: 713 SEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVT 772
+ + SV +W + + + K+ H + V+ + +L+++ D+ VI+ G +
Sbjct: 216 AGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLR 275
Query: 773 KLDH 776
L H
Sbjct: 276 SLHH 279
Score = 42.3 bits (95), Expect = 0.012
Identities = 18/67 (26%), Positives = 33/67 (49%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ C +S D + S V +W + ++ L L GH + FSP++ L+++ S
Sbjct: 200 VYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASY 259
Query: 1029 DRTVVVW 1035
D V++W
Sbjct: 260 DTNVIMW 266
Score = 39.1 bits (87), Expect = 0.11
Identities = 53/250 (21%), Positives = 98/250 (39%), Gaps = 20/250 (8%)
Query: 792 IFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVT---DDNVFLLTLQGDNELHLRTF 848
+ TG DG + W V+ LL ++ + + D++ ++ L++ D L +
Sbjct: 125 VLATGLNDGQIKIWEVQTGLLLLNLSGHQDV-VRDLSFTPSGSLILVSASRDKTLRIWDL 183
Query: 849 IT-GTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXX 907
G + L H V C ++ D S + ++ ++L+S+ S L+R
Sbjct: 184 NKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVV 243
Query: 908 XXXXXXXXFLL--AAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSD 965
LL A+ V ++ +T + L + T Q+ S +I+ L++
Sbjct: 244 SCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHT-QVDPAMDDSDVHISSLRS---- 298
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLS 1025
C S +G A+ L+R+W L A G C TF P+ ++ +
Sbjct: 299 ----VCF--SPEGLYLATVADDRLLRIWALELKTPIAFAPMTNG--LCCTFFPHGGVIAT 350
Query: 1026 GSEDRTVVVW 1035
G+ D V W
Sbjct: 351 GTRDGHVQFW 360
Score = 35.9 bits (79), Expect = 1.1
Identities = 29/146 (19%), Positives = 61/146 (41%), Gaps = 8/146 (5%)
Query: 1021 LLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAM-SSDRARNVHVW-L 1078
L++ +G D + +W++ L GH ++ L G + S+ R + + +W L
Sbjct: 124 LVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDL 183
Query: 1079 VDSGIVLHSATGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE 1135
G + +G + ++ + + G+ SV +WS+ + R+ H
Sbjct: 184 NKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMR---SYTLIRKLEGHQS 240
Query: 1136 RITCFALTADSQHVVTGSMDMSLKVW 1161
+ + DS +VT S D ++ +W
Sbjct: 241 SVVSCDFSPDSALLVTASYDTNVIMW 266
>AF229181-1|AAF71302.1| 404|Homo sapiens CS box-containing WD
protein protein.
Length = 404
Score = 62.5 bits (145), Expect = 1e-08
Identities = 39/149 (26%), Positives = 69/149 (46%), Gaps = 4/149 (2%)
Query: 662 PSGQHLVLAPSAGDPQL--WHIMSNSKVHTFKGHSGSILCMCVTRE-SQYLLTGSEDTSV 718
P LVLA D Q+ W + + + GH + + T S L++ S D ++
Sbjct: 119 PDVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTL 178
Query: 719 IVWDLHTLAVKTKILE-HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+WDL+ + ++L H+ V C + + S++ S + +V + S+ L+ KL+ H
Sbjct: 179 RIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGH 238
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
+ SV S D + +T S D V W+
Sbjct: 239 QSSVVSCDFSPDSALLVTASYDTNVIMWD 267
Score = 55.2 bits (127), Expect = 2e-06
Identities = 40/197 (20%), Positives = 87/197 (44%), Gaps = 14/197 (7%)
Query: 982 ASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPN-NLLVLSGSEDRTVVVWQLADN 1040
A+G G +++W++ T L L+GH + ++F+P+ +L+++S S D+T+ +W L +
Sbjct: 127 ATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKH 186
Query: 1041 SPSL-TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI---D 1096
+ GH + + D S+ ++V +W + S ++ G +S+ D
Sbjct: 187 GKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCD 246
Query: 1097 VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRR---------SVSHAERITCFALTADSQ 1147
+ + V + D +V +W G+ S H + + +
Sbjct: 247 FSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPEGL 306
Query: 1148 HVVTGSMDMSLKVWKLD 1164
++ T + D L++W L+
Sbjct: 307 YLATVADDRLLRIWALE 323
Score = 51.6 bits (118), Expect = 2e-05
Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
Query: 1149 VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINT 1208
+ TG D +K+W++ G L L GH D+V ++ + + +VS S D L +WD+N
Sbjct: 126 LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNK 185
Query: 1209 XXXXXXXXXXXXK-VTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
+ V C ++ D ++ S A +K++ +W +
Sbjct: 186 HGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMR 227
Score = 46.0 bits (104), Expect = 0.001
Identities = 30/137 (21%), Positives = 70/137 (51%), Gaps = 9/137 (6%)
Query: 1074 VHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVL---SDGDNSVRIWSLAGGDNSEDNRR 1129
+ +W V +G++L + +G + D++ +++ + D ++RIW L + + +
Sbjct: 135 IKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDL--NKHGKQIQV 192
Query: 1130 SVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGH-SDIVTCVAVSITN 1188
H + + C +++ D + + + + S+ +W + L + L GH S +V+C +
Sbjct: 193 LSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSC--DFSPD 250
Query: 1189 KTQVVSGSWDCNLIVWD 1205
+V+ S+D N+I+WD
Sbjct: 251 SALLVTASYDTNVIMWD 267
Score = 42.3 bits (95), Expect = 0.012
Identities = 28/124 (22%), Positives = 56/124 (45%), Gaps = 4/124 (3%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQL--WHIMSNSK-VHTFKGHSGSILCMCVTRESQYLLTG 712
R L PSG L+L ++ D L W + + K + GH + C ++ + L +
Sbjct: 157 RDLSFTPSGS-LILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSA 215
Query: 713 SEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVT 772
+ + SV +W + + + K+ H + V+ + +L+++ D+ VI+ G +
Sbjct: 216 AGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLR 275
Query: 773 KLDH 776
L H
Sbjct: 276 SLHH 279
Score = 42.3 bits (95), Expect = 0.012
Identities = 18/67 (26%), Positives = 33/67 (49%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ C +S D + S V +W + ++ L L GH + FSP++ L+++ S
Sbjct: 200 VYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASY 259
Query: 1029 DRTVVVW 1035
D V++W
Sbjct: 260 DTNVIMW 266
Score = 39.1 bits (87), Expect = 0.11
Identities = 53/250 (21%), Positives = 98/250 (39%), Gaps = 20/250 (8%)
Query: 792 IFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVT---DDNVFLLTLQGDNELHLRTF 848
+ TG DG + W V+ LL ++ + + D++ ++ L++ D L +
Sbjct: 125 VLATGLNDGQIKIWEVQTGLLLLNLSGHQDV-VRDLSFTPSGSLILVSASRDKTLRIWDL 183
Query: 849 IT-GTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXX 907
G + L H V C ++ D S + ++ ++L+S+ S L+R
Sbjct: 184 NKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVV 243
Query: 908 XXXXXXXXFLL--AAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSD 965
LL A+ V ++ +T + L + T Q+ S +I+ L++
Sbjct: 244 SCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHT-QVDPAMDDSDVHISSLRS---- 298
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLS 1025
C S +G A+ L+R+W L A G C TF P+ ++ +
Sbjct: 299 ----VCF--SPEGLYLATVADDRLLRIWALELKTPIAFAPMTNG--LCCTFFPHGGVIAT 350
Query: 1026 GSEDRTVVVW 1035
G+ D V W
Sbjct: 351 GTRDGHVQFW 360
Score = 35.9 bits (79), Expect = 1.1
Identities = 29/146 (19%), Positives = 61/146 (41%), Gaps = 8/146 (5%)
Query: 1021 LLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAM-SSDRARNVHVW-L 1078
L++ +G D + +W++ L GH ++ L G + S+ R + + +W L
Sbjct: 124 LVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDL 183
Query: 1079 VDSGIVLHSATGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE 1135
G + +G + ++ + + G+ SV +WS+ + R+ H
Sbjct: 184 NKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMR---SYTLIRKLEGHQS 240
Query: 1136 RITCFALTADSQHVVTGSMDMSLKVW 1161
+ + DS +VT S D ++ +W
Sbjct: 241 SVVSCDFSPDSALLVTASYDTNVIMW 266
>AF163324-1|AAF80478.1| 404|Homo sapiens WSB-2 protein.
Length = 404
Score = 62.5 bits (145), Expect = 1e-08
Identities = 39/149 (26%), Positives = 69/149 (46%), Gaps = 4/149 (2%)
Query: 662 PSGQHLVLAPSAGDPQL--WHIMSNSKVHTFKGHSGSILCMCVTRE-SQYLLTGSEDTSV 718
P LVLA D Q+ W + + + GH + + T S L++ S D ++
Sbjct: 119 PDVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTL 178
Query: 719 IVWDLHTLAVKTKILE-HIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVTKLDHH 777
+WDL+ + ++L H+ V C + + S++ S + +V + S+ L+ KL+ H
Sbjct: 179 RIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGH 238
Query: 778 RGSVTSVKVIQDGNIFITGSQDGTVCTWN 806
+ SV S D + +T S D V W+
Sbjct: 239 QSSVVSCDFSPDSALLVTASYDTNVIMWD 267
Score = 55.2 bits (127), Expect = 2e-06
Identities = 40/197 (20%), Positives = 87/197 (44%), Gaps = 14/197 (7%)
Query: 982 ASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPN-NLLVLSGSEDRTVVVWQLADN 1040
A+G G +++W++ T L L+GH + ++F+P+ +L+++S S D+T+ +W L +
Sbjct: 127 ATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKH 186
Query: 1041 SPSL-TYKGHSSAIQTLLMMSDGRRAMSSDRARNVHVWLVDSGIVLHSATGPSASI---D 1096
+ GH + + D S+ ++V +W + S ++ G +S+ D
Sbjct: 187 GKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCD 246
Query: 1097 VTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRR---------SVSHAERITCFALTADSQ 1147
+ + V + D +V +W G+ S H + + +
Sbjct: 247 FSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPEGL 306
Query: 1148 HVVTGSMDMSLKVWKLD 1164
++ T + D L++W L+
Sbjct: 307 YLATVADDRLLRIWALE 323
Score = 51.6 bits (118), Expect = 2e-05
Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
Query: 1149 VVTGSMDMSLKVWKLDGGKLSQVLVGHSDIVTCVAVSITNKTQVVSGSWDCNLIVWDINT 1208
+ TG D +K+W++ G L L GH D+V ++ + + +VS S D L +WD+N
Sbjct: 126 LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNK 185
Query: 1209 XXXXXXXXXXXXK-VTCVKVTGDGTIAVSCAEDKTLIIWETK 1249
+ V C ++ D ++ S A +K++ +W +
Sbjct: 186 HGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMR 227
Score = 46.0 bits (104), Expect = 0.001
Identities = 30/137 (21%), Positives = 70/137 (51%), Gaps = 9/137 (6%)
Query: 1074 VHVWLVDSGIVLHSATGPSASI-DVTLNMKYAVL---SDGDNSVRIWSLAGGDNSEDNRR 1129
+ +W V +G++L + +G + D++ +++ + D ++RIW L + + +
Sbjct: 135 IKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDL--NKHGKQIQV 192
Query: 1130 SVSHAERITCFALTADSQHVVTGSMDMSLKVWKLDGGKLSQVLVGH-SDIVTCVAVSITN 1188
H + + C +++ D + + + + S+ +W + L + L GH S +V+C +
Sbjct: 193 LSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSC--DFSPD 250
Query: 1189 KTQVVSGSWDCNLIVWD 1205
+V+ S+D N+I+WD
Sbjct: 251 SALLVTASYDTNVIMWD 267
Score = 42.3 bits (95), Expect = 0.012
Identities = 28/124 (22%), Positives = 56/124 (45%), Gaps = 4/124 (3%)
Query: 656 RLLQLAPSGQHLVLAPSAGDPQL--WHIMSNSK-VHTFKGHSGSILCMCVTRESQYLLTG 712
R L PSG L+L ++ D L W + + K + GH + C ++ + L +
Sbjct: 157 RDLSFTPSGS-LILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSA 215
Query: 713 SEDTSVIVWDLHTLAVKTKILEHIAPVLCVAAIVNRSLVISGGDDSAVIITSLVDGALVT 772
+ + SV +W + + + K+ H + V+ + +L+++ D+ VI+ G +
Sbjct: 216 AGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLR 275
Query: 773 KLDH 776
L H
Sbjct: 276 SLHH 279
Score = 42.3 bits (95), Expect = 0.012
Identities = 18/67 (26%), Positives = 33/67 (49%)
Query: 969 ISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLSGSE 1028
+ C +S D + S V +W + ++ L L GH + FSP++ L+++ S
Sbjct: 200 VYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASY 259
Query: 1029 DRTVVVW 1035
D V++W
Sbjct: 260 DTNVIMW 266
Score = 39.1 bits (87), Expect = 0.11
Identities = 53/250 (21%), Positives = 98/250 (39%), Gaps = 20/250 (8%)
Query: 792 IFITGSQDGTVCTWNVENFTLLSTVTAGVPIHIFDVT---DDNVFLLTLQGDNELHLRTF 848
+ TG DG + W V+ LL ++ + + D++ ++ L++ D L +
Sbjct: 125 VLATGLNDGQIKIWEVQTGLLLLNLSGHQDV-VRDLSFTPSGSLILVSASRDKTLRIWDL 183
Query: 849 IT-GTYLHPLKRHKAKVKCFCVAHDSSRVAVGCADQRIYLYSLHSAQLLRTXXXXXXXXX 907
G + L H V C ++ D S + ++ ++L+S+ S L+R
Sbjct: 184 NKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVV 243
Query: 908 XXXXXXXXFLL--AAGGNRVTIYSFHTEDNLTNFRPTKQMKRRQTKSTTNITLLQAEQSD 965
LL A+ V ++ +T + L + T Q+ S +I+ L++
Sbjct: 244 SCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHT-QVDPAMDDSDVHISSLRS---- 298
Query: 966 LIPISCLEVSRDGQLGASGCARGLVRVWQLSTHRLQATLNGHIGHITCVTFSPNNLLVLS 1025
C S +G A+ L+R+W L A G C TF P+ ++ +
Sbjct: 299 ----VCF--SPEGLYLATVADDRLLRIWALELKTPIAFAPMTNG--LCCTFFPHGGVIAT 350
Query: 1026 GSEDRTVVVW 1035
G+ D V W
Sbjct: 351 GTRDGHVQFW 360
Score = 35.9 bits (79), Expect = 1.1
Identities = 29/146 (19%), Positives = 61/146 (41%), Gaps = 8/146 (5%)
Query: 1021 LLVLSGSEDRTVVVWQLADNSPSLTYKGHSSAIQTLLMMSDGRRAM-SSDRARNVHVW-L 1078
L++ +G D + +W++ L GH ++ L G + S+ R + + +W L
Sbjct: 124 LVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDL 183
Query: 1079 VDSGIVLHSATGPSASI---DVTLNMKYAVLSDGDNSVRIWSLAGGDNSEDNRRSVSHAE 1135
G + +G + ++ + + G+ SV +WS+ + R+ H
Sbjct: 184 NKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMR---SYTLIRKLEGHQS 240
Query: 1136 RITCFALTADSQHVVTGSMDMSLKVW 1161
+ + DS +VT S D ++ +W
Sbjct: 241 SVVSCDFSPDSALLVTASYDTNVIMW 266
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.133 0.396
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 198,721,066
Number of Sequences: 224733
Number of extensions: 7920195
Number of successful extensions: 35854
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 762
Number of HSP's successfully gapped in prelim test: 328
Number of HSP's that attempted gapping in prelim test: 20014
Number of HSP's gapped (non-prelim): 10440
length of query: 1448
length of database: 73,234,838
effective HSP length: 99
effective length of query: 1349
effective length of database: 50,986,271
effective search space: 68780479579
effective search space used: 68780479579
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 71 (32.7 bits)
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