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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000452-TA|BGIBMGA000452-PA|IPR000990|Innexin
         (385 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9VAS7 Cluster: Innexin inx3; n=6; Neoptera|Rep: Innexi...   518   e-146
UniRef50_Q9V427 Cluster: Innexin inx2; n=16; Pancrustacea|Rep: I...   329   8e-89
UniRef50_P33085 Cluster: Innexin shaking-B; n=13; Endopterygota|...   288   2e-76
UniRef50_Q2MCL5 Cluster: Innexin inx1; n=1; Homarus gammarus|Rep...   283   4e-75
UniRef50_P27716 Cluster: Innexin inx1; n=7; Neoptera|Rep: Innexi...   281   3e-74
UniRef50_UPI000051A76F Cluster: PREDICTED: similar to Innexin in...   242   9e-63
UniRef50_Q5XLD8 Cluster: Innexin 4; n=2; Bombyx|Rep: Innexin 4 -...   241   3e-62
UniRef50_A2Q094 Cluster: D4.1; n=3; Ichnovirus|Rep: D4.1 - Trano...   233   6e-60
UniRef50_UPI0000D56E12 Cluster: PREDICTED: similar to Innexin in...   224   4e-57
UniRef50_Q16YE3 Cluster: Innexin; n=2; Culicidae|Rep: Innexin - ...   222   1e-56
UniRef50_Q6Q2K9 Cluster: Innexin Vnx-d5.1; n=2; Hyposoter fugiti...   216   9e-55
UniRef50_Q9V3W6 Cluster: Innexin inx7; n=3; Sophophora|Rep: Inne...   214   4e-54
UniRef50_Q6PUP4 Cluster: Innexin Vnx-b17; n=1; Hyposoter fugitiv...   210   3e-53
UniRef50_UPI0000D572E5 Cluster: PREDICTED: similar to Innexin in...   206   6e-52
UniRef50_A2Q0G0 Cluster: Viral innexin-c3.1; n=1; Hyposoter fugi...   204   4e-51
UniRef50_Q6Q2K8 Cluster: Innexin Vnx-d5.2; n=3; Ichnovirus|Rep: ...   201   2e-50
UniRef50_UPI00015B5AB8 Cluster: PREDICTED: similar to gap juncti...   194   4e-48
UniRef50_Q8JV08 Cluster: Innexin-like protein 1; n=2; Campoletis...   188   2e-46
UniRef50_Q80KH3 Cluster: Innexin Vnx-d1; n=1; Campoletis sonoren...   187   5e-46
UniRef50_Q6RXK5 Cluster: Innexin-like protein 4; n=7; Ichnovirus...   185   2e-45
UniRef50_Q9VRX6 Cluster: Innexin inx4; n=2; Sophophora|Rep: Inne...   174   3e-42
UniRef50_Q7Q5R9 Cluster: ENSANGP00000020577; n=1; Anopheles gamb...   170   6e-41
UniRef50_Q174Z8 Cluster: Innexin; n=1; Aedes aegypti|Rep: Innexi...   166   7e-40
UniRef50_Q9VR82 Cluster: Innexin inx6; n=4; Sophophora|Rep: Inne...   115   2e-24
UniRef50_Q8B637 Cluster: Viral innexin; n=3; Ichnovirus|Rep: Vir...   111   4e-23
UniRef50_Q17394 Cluster: Transmembrane protein; n=3; Caenorhabdi...   109   2e-22
UniRef50_Q8I6U1 Cluster: Innexin 2; n=2; Hirudo medicinalis|Rep:...   100   1e-19
UniRef50_Q4VTM8 Cluster: Pannexin 2; n=4; Opisthobranchia|Rep: P...    94   6e-18
UniRef50_Q8MXG9 Cluster: Innexin protein 18, isoform a; n=3; Cae...    91   4e-17
UniRef50_Q19746 Cluster: Innexin-3; n=2; Caenorhabditis|Rep: Inn...    85   4e-15
UniRef50_Q38HR7 Cluster: Innexin 4; n=1; Hirudo medicinalis|Rep:...    84   5e-15
UniRef50_O61787 Cluster: Innexin-16; n=2; Caenorhabditis|Rep: In...    83   2e-14
UniRef50_Q38HR0 Cluster: Innexin 11; n=2; Hirudo medicinalis|Rep...    81   4e-14
UniRef50_Q23027 Cluster: Innexin-5; n=2; Caenorhabditis|Rep: Inn...    81   4e-14
UniRef50_O44887 Cluster: Innexin protein 13; n=2; Caenorhabditis...    80   8e-14
UniRef50_Q38HR6 Cluster: Innexin 5; n=1; Hirudo medicinalis|Rep:...    79   3e-13
UniRef50_Q2L6M6 Cluster: Innexin9; n=2; Dugesia japonica|Rep: In...    79   3e-13
UniRef50_O61715 Cluster: Innexin protein 19, isoform a; n=3; Cae...    79   3e-13
UniRef50_O61786 Cluster: Innexin protein 15; n=2; Caenorhabditis...    77   8e-13
UniRef50_Q8T393 Cluster: Innexin; n=1; Chaetopterus variopedatus...    76   2e-12
UniRef50_Q23157 Cluster: Innexin-11; n=2; Caenorhabditis|Rep: In...    76   2e-12
UniRef50_Q5C7A4 Cluster: SJCHGC08200 protein; n=1; Schistosoma j...    74   6e-12
UniRef50_Q2L6M2 Cluster: Innexin1; n=2; Dugesiidae|Rep: Innexin1...    70   1e-10
UniRef50_O01634 Cluster: Innexin-12; n=2; Caenorhabditis|Rep: In...    69   2e-10
UniRef50_Q38HR8 Cluster: Innexin 3; n=1; Hirudo medicinalis|Rep:...    69   3e-10
UniRef50_Q29ZM7 Cluster: Pannexin 4; n=3; Opisthobranchia|Rep: P...    69   3e-10
UniRef50_Q2L6M8 Cluster: Innexin7; n=2; Eukaryota|Rep: Innexin7 ...    68   5e-10
UniRef50_Q2L6N2 Cluster: Innexin2; n=1; Dugesia japonica|Rep: In...    67   6e-10
UniRef50_Q9U3N4 Cluster: Innexin-6; n=2; Caenorhabditis|Rep: Inn...    66   2e-09
UniRef50_Q2L6M9 Cluster: Innexin5; n=3; Platyhelminthes|Rep: Inn...    65   3e-09
UniRef50_Q9U3K5 Cluster: Innexin-2; n=2; Caenorhabditis|Rep: Inn...    65   3e-09
UniRef50_Q2L6N1 Cluster: Innexin3; n=2; Dugesia japonica|Rep: In...    63   1e-08
UniRef50_Q8I6U2 Cluster: Innexin 1; n=1; Hirudo medicinalis|Rep:...    62   2e-08
UniRef50_Q9N3R5 Cluster: Innexin protein 22; n=2; Caenorhabditis...    61   5e-08
UniRef50_Q5DA25 Cluster: SJCHGC09647 protein; n=4; Schistosoma j...    60   7e-08
UniRef50_Q38HR5 Cluster: Innexin 6; n=1; Hirudo medicinalis|Rep:...    60   1e-07
UniRef50_Q2L6M5 Cluster: Innexin10; n=1; Dugesia japonica|Rep: I...    60   1e-07
UniRef50_Q22549 Cluster: Innexin-10; n=3; Caenorhabditis|Rep: In...    60   1e-07
UniRef50_P91827 Cluster: Putative uncharacterized protein inx-20...    59   2e-07
UniRef50_Q8MWD8 Cluster: Innexin 1; n=2; Penaeus monodon|Rep: In...    58   3e-07
UniRef50_Q03412 Cluster: Innexin unc-7; n=4; Caenorhabditis|Rep:...    57   7e-07
UniRef50_Q38HQ9 Cluster: Innexin 12; n=1; Hirudo medicinalis|Rep...    56   1e-06
UniRef50_O61966 Cluster: Innexin protein 4; n=2; Caenorhabditis|...    56   1e-06
UniRef50_Q23593 Cluster: Innexin-8; n=3; Caenorhabditis|Rep: Inn...    55   4e-06
UniRef50_Q2L6N0 Cluster: Innexin4; n=1; Dugesia japonica|Rep: In...    54   8e-06
UniRef50_Q3KZ46 Cluster: SJCHGC07836 protein; n=1; Schistosoma j...    53   1e-05
UniRef50_O62136 Cluster: Innexin-14; n=3; Caenorhabditis|Rep: In...    53   1e-05
UniRef50_Q2L6M4 Cluster: Innexin11; n=2; Dugesiidae|Rep: Innexin...    52   3e-05
UniRef50_O61788 Cluster: Innexin-17; n=3; Caenorhabditis|Rep: In...    52   3e-05
UniRef50_Q38HR3 Cluster: Innexin 8; n=1; Hirudo medicinalis|Rep:...    50   8e-05
UniRef50_Q2VTE9 Cluster: Pannexin 6; n=1; Aplysia californica|Re...    50   8e-05
UniRef50_Q2VTF0 Cluster: Pannexin 5; n=1; Aplysia californica|Re...    49   2e-04
UniRef50_UPI00015B4966 Cluster: PREDICTED: similar to ENSANGP000...    47   7e-04
UniRef50_Q21123 Cluster: Innexin-7; n=2; Caenorhabditis|Rep: Inn...    47   7e-04
UniRef50_Q5D8R4 Cluster: SJCHGC06704 protein; n=1; Schistosoma j...    46   0.001
UniRef50_UPI0000DB719F Cluster: PREDICTED: similar to Innexin sh...    46   0.002
UniRef50_Q2EMV6 Cluster: Innexin 1; n=1; Hydra vulgaris|Rep: Inn...    42   0.021
UniRef50_Q27295 Cluster: Innexin eat-5; n=2; Caenorhabditis|Rep:...    42   0.021
UniRef50_Q61ER8 Cluster: Putative uncharacterized protein CBG119...    38   0.34 
UniRef50_A2ESC5 Cluster: Putative uncharacterized protein; n=1; ...    36   2.4  
UniRef50_P96742 Cluster: YwtG protein; n=5; Bacillales|Rep: YwtG...    35   4.1  
UniRef50_Q7SFU1 Cluster: Putative uncharacterized protein NCU007...    34   5.5  
UniRef50_A7ASB1 Cluster: Putative uncharacterized protein; n=1; ...    33   9.5  

>UniRef50_Q9VAS7 Cluster: Innexin inx3; n=6; Neoptera|Rep: Innexin
           inx3 - Drosophila melanogaster (Fruit fly)
          Length = 395

 Score =  518 bits (1279), Expect = e-146
 Identities = 237/397 (59%), Positives = 311/397 (78%), Gaps = 14/397 (3%)

Query: 1   MAVFGLVSSVAGFVKVRYLIDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIAC 60
           MAVFG+VS+V+GF+K+RYL+DKAVIDNMVFR HYRIT+AILF CCI+VTANNLIG+PI+C
Sbjct: 1   MAVFGMVSAVSGFIKIRYLLDKAVIDNMVFRCHYRITTAILFTCCIIVTANNLIGDPISC 60

Query: 61  ISDGANPGHVINTFCWITYTFTMPNTTSKT----AAHPGLGDD-NDEKRIHSYYQWVPFM 115
           I+DGA P HVINTFCWITYT+T+P    +      A PGLG++   EKR HSYYQWVPF+
Sbjct: 61  INDGAIPMHVINTFCWITYTYTIPGQQHRQIGTDVAGPGLGNEYGQEKRYHSYYQWVPFV 120

Query: 116 LFFQGLLFYIPHWIWKNWEEGKVRLISEGMRGTMASIADD-KNNRQNRLVQYLLDTLHMH 174
           LFFQGL+FY+PHW+WKN E+GK+R+I++G+RG M S+ DD + +RQ+R+++Y +++L+ H
Sbjct: 121 LFFQGLMFYVPHWVWKNMEDGKIRMITDGLRG-MVSVPDDYRRDRQDRILKYFVNSLNTH 179

Query: 175 NTYSFGYFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFP 234
           N YSF YFFCE+LNF NV+ NIF +D FLGGAF++YGTDV++FSNM+Q++R DPMIE+FP
Sbjct: 180 NGYSFAYFFCELLNFINVIVNIFMVDKFLGGAFMSYGTDVLKFSNMDQDKRFDPMIEIFP 239

Query: 235 RITKCTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVC 294
           R+TKCTFHKFG SG++QKHD LCVLALNILNEK            + +SG+A++YS  V 
Sbjct: 240 RLTKCTFHKFGPSGSVQKHDTLCVLALNILNEKIYIFLWFWFIILATISGVAVLYSLVVI 299

Query: 295 LLPSTRETILKRRFRFGTPNGVEALVRKTQVGDFLLLHLLGQNMSLRVFGEVLDELSRRL 354
           ++P+TRETI+KR +R      +  LVR+ ++GDFL+LH L QN+S R + ++L +L   L
Sbjct: 300 MMPTTRETIIKRSYRSAQRKEIAGLVRRLEIGDFLILHFLSQNLSTRSYSDMLQQLCGLL 359

Query: 355 NLGSHAPSAPSTLEM----APIYPDIDKY--SKETET 385
              S  PSAPSTLEM     PIYP ++ +   KETET
Sbjct: 360 G-ASRTPSAPSTLEMNRISHPIYPPVETFGGGKETET 395


>UniRef50_Q9V427 Cluster: Innexin inx2; n=16; Pancrustacea|Rep:
           Innexin inx2 - Drosophila melanogaster (Fruit fly)
          Length = 367

 Score =  329 bits (808), Expect = 8e-89
 Identities = 156/365 (42%), Positives = 229/365 (62%), Gaps = 13/365 (3%)

Query: 3   VFGLVSSVAGFVKVRYLIDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACIS 62
           +F +  SV G +K    ID+  IDN VFRMHY+ T  IL    +LVT+   IG+PI CI 
Sbjct: 1   MFDVFGSVKGLLK----IDQVCIDNNVFRMHYKATVIILIAFSLLVTSRQYIGDPIDCIV 56

Query: 63  DGANPGHVINTFCWITYTFTMPNT----TSKTAAHPGLG---DDNDEKRIHSYYQWVPFM 115
           D    G V++T+CWI  TFT+P      T +    PG+G   +  DE + H YYQWV F+
Sbjct: 57  DEIPLG-VMDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFV 115

Query: 116 LFFQGLLFYIPHWIWKNWEEGKVRLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHN 175
           LFFQ +LFY+P ++WK+WE G+++++   +   + +  + KN+R+  LV Y +  L+ HN
Sbjct: 116 LFFQAILFYVPRYLWKSWEGGRLKMLVMDLNSPIVN-DECKNDRKKILVDYFIGNLNRHN 174

Query: 176 TYSFGYFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPR 235
            Y+F +F CE LNF NV+G I+F+D FL G F TYG+DV++F+ +  ++R DPM  VFP+
Sbjct: 175 FYAFRFFVCEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPK 234

Query: 236 ITKCTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCL 295
           +TKCTFHK+G SG++Q HD LCVL LNI+NEK            S++SG++L+Y  AV  
Sbjct: 235 VTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLIYRIAVVA 294

Query: 296 LPSTRETILKRRFRFGTPNGVEALVRKTQVGDFLLLHLLGQNMSLRVFGEVLDELSRRLN 355
            P  R  +L+ R R      VE +  K  +GD+ LL+ LG+N+   ++ EV+ +LSR ++
Sbjct: 295 GPKLRHLLLRARSRLAESEEVELVANKCNIGDWFLLYQLGKNIDPLIYKEVISDLSREMS 354

Query: 356 LGSHA 360
              H+
Sbjct: 355 GDEHS 359


>UniRef50_P33085 Cluster: Innexin shaking-B; n=13;
           Endopterygota|Rep: Innexin shaking-B - Drosophila
           melanogaster (Fruit fly)
          Length = 372

 Score =  288 bits (706), Expect = 2e-76
 Identities = 130/341 (38%), Positives = 209/341 (61%), Gaps = 8/341 (2%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHVINTFCWITYTFTMPN 85
           D++VFR+HY IT  IL    +++T    +G PI C+     P  V+NT+CWI  T+T+ +
Sbjct: 20  DSIVFRLHYSITVMILMSFSLIITTRQYVGNPIDCVHTKDIPEDVLNTYCWIQSTYTLKS 79

Query: 86  TTSK----TAAHPGLGD-DND--EKRIHSYYQWVPFMLFFQGLLFYIPHWIWKNWEEGKV 138
              K    +  +PG+G+ D D  +K+ + YYQWV F LFFQ +LFY P W+WK+WE GK+
Sbjct: 80  LFLKKQGVSVPYPGIGNSDGDPADKKHYKYYQWVCFCLFFQAILFYTPRWLWKSWEGGKI 139

Query: 139 RLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYSFGYFFCEVLNFANVVGNIFF 198
             +   +   + S A+ K  ++  L+ YL + L  HN +++ Y+ CE+L   NV+G +F 
Sbjct: 140 HALIMDLDIGICSEAE-KKQKKKLLLDYLWENLRYHNWWAYRYYVCELLALINVIGQMFL 198

Query: 199 LDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFGASGTIQKHDALCV 258
           ++ F  G F+T+G  V+ +   +QE R DPMI +FPR+TKCTF K+G+SG ++KHDA+C+
Sbjct: 199 MNRFFDGEFITFGLKVIDYMETDQEDRMDPMIYIFPRMTKCTFFKYGSSGEVEKHDAICI 258

Query: 259 LALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPSTRETILKRRFRFGTPNGVEA 318
           L LN++NEK            + ++ L L+Y   +   P  R  + + RFR    + +E 
Sbjct: 259 LPLNVVNEKIYIFLWFWFILLTFLTLLTLIYRVVIIFSPRMRVYLFRMRFRLVRRDAIEI 318

Query: 319 LVRKTQVGDFLLLHLLGQNMSLRVFGEVLDELSRRLNLGSH 359
           +VR++++GD+ LL+LLG+N+   +F +V+ +L+ RL    H
Sbjct: 319 IVRRSKMGDWFLLYLLGENIDTVIFRDVVQDLANRLGHNQH 359


>UniRef50_Q2MCL5 Cluster: Innexin inx1; n=1; Homarus gammarus|Rep:
           Innexin inx1 - Homarus gammarus (European lobster)
           (Homarus vulgaris)
          Length = 367

 Score =  283 bits (695), Expect = 4e-75
 Identities = 144/340 (42%), Positives = 207/340 (60%), Gaps = 12/340 (3%)

Query: 23  AVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHVINTFCWITYTFT 82
           A +DN VF +HYR+T  +  +   LVTA  LIG PI CIS  A P +V+NTFC+I  TF+
Sbjct: 16  AQVDNAVFHLHYRVTFVVFIVSGALVTAKELIGAPIQCISK-AVPTNVLNTFCFIMSTFS 74

Query: 83  MPNTTSKT----AAHPGLG--DDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKNWEEG 136
           +P    K      A+PG+G  +D DE   H+YYQWVPF+L  Q ++FY+P ++WKN E G
Sbjct: 75  VPRHWDKPLGDGVAYPGVGMHEDEDEIVYHAYYQWVPFVLVLQAIMFYVPRYLWKNMEGG 134

Query: 137 KVRLISEGM-RGTMASIADDKNNRQNRLVQYLLDTLHMHNTYSFGYFFCEVLNFANVVGN 195
               I  G+ + TM   A  K ++   L QY++  LHMH  ++  +F CE L    VVGN
Sbjct: 135 LFTTILAGLDKLTMDESARHKKHKI--LSQYMVKHLHMHMNWAIRFFLCEALCLVVVVGN 192

Query: 196 IFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFGASGTIQKHDA 255
           I+F D FL G F+ YGT+V+ F +M+ E+R DPM  +FPR+TKCTF KFG+SGT++ HD 
Sbjct: 193 IYFTDLFLDGTFMKYGTEVINFPDMDPEKRVDPMTRIFPRVTKCTFRKFGSSGTLETHDT 252

Query: 256 LCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPSTRETILKRRFRF-GTPN 314
           +CVLA+NI+NEK            + ++   LVY   +      R  +L+ R  + G PN
Sbjct: 253 MCVLAVNIINEKIYIFIWFWLVFLTAITAAWLVYRLIIIASSEVRFKLLQVRGSWAGRPN 312

Query: 315 GVEALVRKTQVGDFLLLHLLGQNMSLRVFGEVLDELSRRL 354
            ++ + +K  +GD+ L++ LG+NM   V+ E L E ++ L
Sbjct: 313 -LDLIAKKCNLGDWFLIYHLGRNMEPLVYAEFLKEFAKEL 351


>UniRef50_P27716 Cluster: Innexin inx1; n=7; Neoptera|Rep: Innexin
           inx1 - Drosophila melanogaster (Fruit fly)
          Length = 362

 Score =  281 bits (688), Expect = 3e-74
 Identities = 128/341 (37%), Positives = 209/341 (61%), Gaps = 9/341 (2%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHVINTFCWITYTFTMPN 85
           DN VFR+H   T+ +L  C +++TA   +G+PI+CI +G  P HV+NTFCWI  TFTMP+
Sbjct: 20  DNAVFRLHNSFTTVLLLTCSLIITATQYVGQPISCIVNGVPP-HVVNTFCWIHSTFTMPD 78

Query: 86  T----TSKTAAHPGLGDD---NDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKNWEEGKV 138
                  +  AHPG+ +D    D K+ ++YYQWV F+LFFQ +  Y P ++W  +E G +
Sbjct: 79  AFRRQVGREVAHPGVANDFGDEDAKKYYTYYQWVCFVLFFQAMACYTPKFLWNKFEGGLM 138

Query: 139 RLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYSFGYFFCEVLNFANVVGNIFF 198
           R+I  G+  T+ +  ++K  +++ L+ YL+  +  H  Y+  Y+ CE L   N++  ++ 
Sbjct: 139 RMIVMGLNITICT-REEKEAKRDALLDYLIKHVKRHKLYAIRYWACEFLCCINIIVQMYL 197

Query: 199 LDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFGASGTIQKHDALCV 258
           ++ F  G FL+YGT++++ S++ QEQR DPM+ VFPR+TKCTFHK+G SG++QKHD+LC+
Sbjct: 198 MNRFFDGEFLSYGTNIMKLSDVPQEQRVDPMVYVFPRVTKCTFHKYGPSGSLQKHDSLCI 257

Query: 259 LALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPSTRETILKRRFRFGTPNGVEA 318
           L LNI+NEK             V+    +V+   +  +P  R  +L    R        +
Sbjct: 258 LPLNIVNEKTYVFIWFWFWILLVLLIGLIVFRGCIIFMPKFRPRLLNASNRMIPMEICRS 317

Query: 319 LVRKTQVGDFLLLHLLGQNMSLRVFGEVLDELSRRLNLGSH 359
           L RK  +GD+ L+++LG+N+   ++ +V+ E ++++    H
Sbjct: 318 LSRKLDIGDWWLIYMLGRNLDPVIYKDVMSEFAKQVEPSKH 358


>UniRef50_UPI000051A76F Cluster: PREDICTED: similar to Innexin inx7
           (Innexin-7) (Gap junction protein prp7) (Pas-related
           protein 7); n=2; Apocrita|Rep: PREDICTED: similar to
           Innexin inx7 (Innexin-7) (Gap junction protein prp7)
           (Pas-related protein 7) - Apis mellifera
          Length = 408

 Score =  242 bits (593), Expect = 9e-63
 Identities = 138/380 (36%), Positives = 210/380 (55%), Gaps = 33/380 (8%)

Query: 3   VFGLVSSVAGFVKVRYLIDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACIS 62
           V    S +   VK +   D   IDN+VF+MHYR T  +L +  +LVTA   IGE I CI+
Sbjct: 4   VLATFSVLKDHVKWKVSQDSVAIDNLVFKMHYRFTFLMLLIATLLVTARQFIGEHIRCIA 63

Query: 63  D-GANPG--HVINTFCWITYTFTMPNTTSKTA------AHPGLGDDNDEKRI--HSYYQW 111
             G +     VINTFC+ T T+T+    +KT+      AHPG+G    E  +  H+YYQW
Sbjct: 64  GHGMSDDVVKVINTFCFFTSTYTVTKHLNKTSVELGEIAHPGVGPATSEDSVVHHAYYQW 123

Query: 112 VPFMLFFQGLLFYIPHWIWKNWEEGKVRLISEGMRGTMASIADDKNNRQN---------- 161
           VPF+LFFQ + FY PH++W+N E G+++ +  G+     ++ +     +N          
Sbjct: 124 VPFVLFFQAIFFYAPHYLWRNVEGGRLKTLVTGLHTASMALRETSLQTENGISIMSKDEC 183

Query: 162 ----RLVQY-LLDTLHMHNTYSFGYFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVR 216
               R +++  L+ +H++  +++    CEVLNF NV+  I+  D FLGGAFL  G  +  
Sbjct: 184 DEKIRQIRHAFLNRIHLNRPWAYYLGLCEVLNFINVLLQIYLTDWFLGGAFLGLGQMLA- 242

Query: 217 FSNMNQEQRTDPMIEVFPRITKCTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXX 276
            +  ++E + +P+  VFP++TKC FHK+G SGTIQ HDALC++ALNI+NEK         
Sbjct: 243 -NRGSEEGQVEPLDIVFPKVTKCIFHKYGPSGTIQNHDALCIMALNIINEKIYVFLWYWY 301

Query: 277 XXXSVVSGLALVYSAAVCLLPSTRETILKRRFRFGTPN-----GVEALVRKTQVGDFLLL 331
              SV++GL L++     +L +  E   K  F    P       V A+  +   GD++ L
Sbjct: 302 IILSVITGLGLLWRLLTMVLHARSELFNKLVFSMACPGKYNPWNVLAVTHECHYGDWVFL 361

Query: 332 HLLGQNMSLRVFGEVLDELS 351
           + + +NM   VF E+L +L+
Sbjct: 362 YYIAKNMDNYVFRELLVKLA 381


>UniRef50_Q5XLD8 Cluster: Innexin 4; n=2; Bombyx|Rep: Innexin 4 -
           Bombyx mori (Silk moth)
          Length = 371

 Score =  241 bits (589), Expect = 3e-62
 Identities = 127/346 (36%), Positives = 197/346 (56%), Gaps = 18/346 (5%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACIS--DGANPGHVINTFCWITYTFTM 83
           DN +FRMHY++T  IL +  +LVT+    GEPI C+S  D  N    +N++CWI  T+T+
Sbjct: 20  DNNIFRMHYKLTVIILLVFTLLVTSKQFFGEPIHCMSGNDKGNDKDAVNSYCWIYGTYTL 79

Query: 84  PN----TTSKTAAHPGLG---DDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKNWEEG 136
            +       +  A+ G+G    D+DE+  H+YYQWV F+L  Q  +FY P ++WK WE G
Sbjct: 80  KSQLLGVEGRHMAYVGVGPAKSDDDEQIKHTYYQWVCFVLLGQATMFYAPRYLWKMWEGG 139

Query: 137 KVRLISEGMRGTMASIADDKNNRQNRLVQYLLDT-LHMHNTYSFGYFFCEVLNFANVVGN 195
           +++ ++  +   M S  D    R+  LV Y   T ++ HN Y+  Y FCE+LN  NVVG 
Sbjct: 140 RLKALAADLSSPMVS-KDWSEFRRKELVSYFNYTNMYTHNMYALRYAFCELLNLVNVVGQ 198

Query: 196 IFFLDTFLGGAFLTYGTDVVRF-------SNMNQEQRTDPMIEVFPRITKCTFHKFGASG 248
           IF LD FLGG+F  YG  V  F       ++       +PM E FP++TKC    +G SG
Sbjct: 199 IFILDLFLGGSFRNYGAAVAAFTHTPRIPNDFTNFTSVNPMDEFFPKLTKCWLRNYGPSG 258

Query: 249 TIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPSTRETILKRRF 308
           +++  D LCVL LNI+NEK            +  S LA+V+   + +L   R  +++ + 
Sbjct: 259 SLELKDRLCVLPLNIVNEKIFVILWFWLIILTAFSILAVVFRFLLLILYPLRTVMIRGQI 318

Query: 309 RFGTPNGVEALVRKTQVGDFLLLHLLGQNMSLRVFGEVLDELSRRL 354
           R+   + V  +V++   GD+ +LHLLG+NM+  +F +++ EL++ +
Sbjct: 319 RYVKRSVVSRIVKRFGFGDWFILHLLGKNMNPIIFKDLVLELAKEI 364


>UniRef50_A2Q094 Cluster: D4.1; n=3; Ichnovirus|Rep: D4.1 -
           Tranosema rostrales ichnovirus
          Length = 376

 Score =  233 bits (570), Expect = 6e-60
 Identities = 117/359 (32%), Positives = 198/359 (55%), Gaps = 14/359 (3%)

Query: 7   VSSVAGFVKVRYLIDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGAN 66
           +S+V G +KV+ ++    IDN VFR+HY+IT  +L    ++ T+    G+P+ C      
Sbjct: 5   LSTVRGLLKVQSIL----IDNSVFRLHYKITVVVLLAFSLITTSGQFFGDPMDCYFPDY- 59

Query: 67  PGHVINTFCWITYTFTMPNTTSKTAA----HPGLGDDNDEK--RIHSYYQWVPFMLFFQG 120
           P   +NT+C+I  TF +  + +  A     HPGL    +E   + + YYQWV   LF Q 
Sbjct: 60  PSTSLNTYCYIQSTFLVARSATHAAGKGIPHPGLTGHTEEDTLKFYGYYQWVFITLFVQA 119

Query: 121 LLFYIPHWIWKNWEEGKVRLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYSFG 180
           + FY PH+IWK  E G +++++  +   + S    + N +  LV+Y   TL  HN+Y++ 
Sbjct: 120 IFFYAPHYIWKASEGGTMKMLAIDIASPVVSAECIRKNTEP-LVEYFCTTLRSHNSYAYK 178

Query: 181 YFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQ--EQRTDPMIEVFPRITK 238
           YF CEVLN  N++G I F++ F+G  F  YG  V+ F    Q  E+ T+PM E+FP +TK
Sbjct: 179 YFLCEVLNLINIIGQICFINAFIGEEFRYYGIYVLIFKWKEQLKERMTNPMEEIFPTVTK 238

Query: 239 CTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPS 298
           C++  +G SG++Q  + +CVLA N +N+K            +++S L ++Y     + PS
Sbjct: 239 CSYKTYGPSGSLQNREGICVLAQNSVNQKIYVFLWFWFNILAIISALVIIYRIVTIIFPS 298

Query: 299 TRETILKRRFRFGTPNGVEALVRKTQVGDFLLLHLLGQNMSLRVFGEVLDELSRRLNLG 357
            R    +   +      +  +V K ++GD+ L+ +L QN++   + E++  +++R + G
Sbjct: 299 IRVYEFRSSSKMNRARDINVVVHKLRIGDWFLMRMLQQNINSLAYRELIFCMAQRFDSG 357


>UniRef50_UPI0000D56E12 Cluster: PREDICTED: similar to Innexin inx2
           (Innexin-2) (Gap junction protein prp33) (Pas-related
           protein 33); n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to Innexin inx2 (Innexin-2) (Gap junction
           protein prp33) (Pas-related protein 33) - Tribolium
           castaneum
          Length = 367

 Score =  224 bits (547), Expect = 4e-57
 Identities = 121/340 (35%), Positives = 191/340 (56%), Gaps = 21/340 (6%)

Query: 20  IDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHVINTFCWITY 79
           +++   DN VFR+HY++T  +L +  IL+T+    G+PI C  +      ++ T+CWI  
Sbjct: 14  VEQIRTDNNVFRLHYKLTVIMLIVFSILLTSKQYFGDPINCKVEENRD--IVETYCWIHG 71

Query: 80  TFTMPNTTS-KTAAHPGLGDDN----------DEKRI-HSYYQWVPFMLFFQGLLFYIPH 127
           T+   +T S K+   PGLG DN          D+K I   YYQWV  +  FQ LLFY+P 
Sbjct: 72  TYIRRDTLSGKSGFIPGLGPDNRDIRPWMRSPDDKIIWQKYYQWVCIVFCFQALLFYLPR 131

Query: 128 WIWKNWEEGKVRLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYSFGYFFCEVL 187
           ++WK WE G++RL+   +   + + + +   + ++++QY+++  + H  Y+  Y  CE+L
Sbjct: 132 YLWKTWEGGRLRLLVSDLNTPLVTASWNPTTK-SQMIQYIINGKYFHTLYAIRYVVCEIL 190

Query: 188 NFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFGAS 247
           N ANV+  IF +DTFLGG F  YG  V    ++N       M EVFP++TKC +  +G S
Sbjct: 191 NLANVILQIFLMDTFLGGQFALYGFKVFANGDINA------MNEVFPKLTKCQYRFYGPS 244

Query: 248 GTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPSTRETILKRR 307
           G+    DALC+L LNILNEK            S V+ L+L+Y   V  +P  R  +L  +
Sbjct: 245 GSEVNRDALCILPLNILNEKLFIVLWFWLFFLSGVTFLSLIYRFVVVCVPKLRVYLLMAQ 304

Query: 308 FRFGTPNGVEALVRKTQVGDFLLLHLLGQNMSLRVFGEVL 347
            RF       ++++K   GDF +L+ +G+N++  VF E++
Sbjct: 305 ARFIGSKQATSIIQKFSYGDFFVLYHVGKNVNPIVFRELV 344


>UniRef50_Q16YE3 Cluster: Innexin; n=2; Culicidae|Rep: Innexin -
           Aedes aegypti (Yellowfever mosquito)
          Length = 407

 Score =  222 bits (542), Expect = 1e-56
 Identities = 130/369 (35%), Positives = 195/369 (52%), Gaps = 34/369 (9%)

Query: 25  IDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHVINTFCWITYTFTMP 84
           IDN+ F+ HYR T  IL +C +LVT+   IGE I CI+ G+ P HVINTFC+ T TFT+ 
Sbjct: 21  IDNVAFKFHYRATFTILLVCTLLVTSRQYIGEHIRCITGGSIPEHVINTFCFFTTTFTVV 80

Query: 85  NTTSKT------AAHPGLGD--DNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKNWEEG 136
              +++        HPG+G    +D  + H+YYQWVPF+LF Q +LFY PH+IW+N E G
Sbjct: 81  RHFNESMLQDGNIPHPGVGHTYSDDPIKYHAYYQWVPFVLFIQAILFYGPHYIWRNMEGG 140

Query: 137 KVRLISEGMRGTMAS---------IADDK-----NNRQNRLVQYLLDTLHMH----NTYS 178
           K++ + +G+R    S           D K      +  ++ ++   +  H H    + ++
Sbjct: 141 KIKRLVDGLRMVEVSRYYKQNKVVTFDSKYTLYPKSELDKKIEIACEAFHKHIILNHMWA 200

Query: 179 FGYFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITK 238
             +  CE LN  NV+  ++F + FLGG F   G D   F   +     D +  +FP+ITK
Sbjct: 201 SKHVLCETLNLVNVLAQVWFTNKFLGGRFYRLGLD---FIEEDFSGSMDVLDTIFPKITK 257

Query: 239 CTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVY--SAAVCLL 296
           C FHK+G SGTIQKHDALCV+ALN++NEK              VS  ALV+  +   C  
Sbjct: 258 CHFHKYGPSGTIQKHDALCVMALNVINEKIFTFLWFWYAVLIFVSISALVWRITTLTCHA 317

Query: 297 PSTR-ETILKRRFRFGTPNG--VEALVRKTQVGDFLLLHLLGQNMSLRVFGEVLDELSRR 353
            S +  + +  +   G  N   ++ +       D++ L+ LG+N+   +F  +   + +R
Sbjct: 318 RSVKFNSFVFCKVSPGMLNSYDLDFITESLSFSDWMFLYYLGRNIDSHLFKALFRGIIQR 377

Query: 354 LNLGSHAPS 362
            N   H  S
Sbjct: 378 FNGTRHESS 386


>UniRef50_Q6Q2K9 Cluster: Innexin Vnx-d5.1; n=2; Hyposoter fugitivus
           ichnovirus|Rep: Innexin Vnx-d5.1 - Hyposoter fugitivus
           ichnovirus
          Length = 375

 Score =  216 bits (527), Expect = 9e-55
 Identities = 105/351 (29%), Positives = 188/351 (53%), Gaps = 9/351 (2%)

Query: 3   VFGLVSSVAGFVKVRYLIDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACIS 62
           +F +V + + F++    +     D    R+HY+IT+ IL    +L++  +  G+ + C  
Sbjct: 13  LFAMVDT-SSFLRGLLKVQSIATDENFNRLHYKITATILLFFSLLISWAHFSGDAVDCDF 71

Query: 63  DGANPGHVINTFCWITYTFTMPN----TTSKTAAHPGLGDD--NDEKRIHSYYQWVPFML 116
            G +    ++T+C+   TF +      T  +   HPG+     +D+ + + YY WV  +L
Sbjct: 72  PGRSH-RSLDTYCYAHSTFLVERFITGTEREYVPHPGVAAHVKDDKLKFYGYYGWVYIVL 130

Query: 117 FFQGLLFYIPHWIWKNWEEGKVRLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNT 176
           F Q L FYIPH++WK+WE GK+++++  +   +      K N +  L+ Y   TLH HN+
Sbjct: 131 FLQALSFYIPHYMWKSWEGGKLKMLTVELTSPVLRKDCIKENTEP-LIDYFCSTLHSHNS 189

Query: 177 YSFGYFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRI 236
           Y++ YFFCE+LNF N VG I F++ F+G  F+ YG D++ F+       TDPM  +FP +
Sbjct: 190 YAYKYFFCEMLNFINAVGQICFMNVFIGEDFVYYGIDIIMFNREQIVGMTDPMERLFPVM 249

Query: 237 TKCTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLL 296
           TKCT+  FG SGT++  + +C L  N LN +            +++S   ++    + + 
Sbjct: 250 TKCTYQTFGPSGTLENLEGMCTLTQNALNARIYAFLWFWFYILAIISAFVVICRVVILIS 309

Query: 297 PSTRETILKRRFRFGTPNGVEALVRKTQVGDFLLLHLLGQNMSLRVFGEVL 347
            S R  + +      +   ++ +  K ++GD+ LLH+L QN++   + +++
Sbjct: 310 RSIRLYVFQTSSSLNSGGDIDVVFHKLRIGDWFLLHMLQQNINPLAYKQLI 360


>UniRef50_Q9V3W6 Cluster: Innexin inx7; n=3; Sophophora|Rep: Innexin
           inx7 - Drosophila melanogaster (Fruit fly)
          Length = 438

 Score =  214 bits (522), Expect = 4e-54
 Identities = 139/400 (34%), Positives = 215/400 (53%), Gaps = 35/400 (8%)

Query: 8   SSVAGFVKVRYLIDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANP 67
           SSV  ++K  + + + VIDN+VF++HYR T  IL +  +L+T+   IGE I C+SDG   
Sbjct: 6   SSVRQYLK--FDLTRVVIDNIVFKLHYRWTFVILLVATLLITSRQYIGEHIQCLSDGV-V 62

Query: 68  GHVINTFCWITYTFTMPNTTSKTAAHPG-----LGDDNDEK---RIHSYYQWVPFMLFFQ 119
             VINTFC+ T TFT+    ++TA  PG     +G  + EK   + H+YYQWVPF+LFFQ
Sbjct: 63  SPVINTFCFFTPTFTVVRDQNQTAYRPGSEPPGIGAFDPEKDTIKRHAYYQWVPFVLFFQ 122

Query: 120 GLLFYIPHWIWKNWEEGKVRLISEGMR--GTMASIADDK--------------NNRQNRL 163
            L FYIPH +WK+WE G+++ +  G+R  G    + +D                 R   +
Sbjct: 123 ALCFYIPHALWKSWEGGRIKALVFGLRMVGLTRYLKNDSLRIGKLNIPSMAEAEERVKDI 182

Query: 164 VQYLLDTLHMHNTYSFGYFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQE 223
            + ++D + ++ ++     F EVLN  N++  I + + FLGG FLT G   ++ +  + E
Sbjct: 183 RRTMIDRMRLNQSWGAHLVFAEVLNLINLLLQITWTNRFLGGQFLTLGPHALK-NRWSDE 241

Query: 224 QRTDPMIEVFPRITKCTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVS 283
                +  VFP+ITKC FHKFG SG+IQ HDALCV+ALNI+NEK             +V+
Sbjct: 242 LSVLDL--VFPKITKCKFHKFGDSGSIQMHDALCVMALNIMNEKIYIILWFWYAFLLIVT 299

Query: 284 GLALVYS-AAVCL---LPSTRETILKRRFRFGTPNGVEALVRKTQVGDFLLLHLLGQNMS 339
            L L++    +C    +  TR ++   +      N + A++ K    +++ L  L  N+S
Sbjct: 300 VLGLLWRILTLCFYRNVTFTRWSLYWAKPGQLDENELLAVIDKCNFSNWMFLFFLRSNLS 359

Query: 340 LRVFGEVLDELSRRLNLGSHAPSAPSTLEMAPIYPDIDKY 379
             +F +V+  L+       H     +  E AP  P  ++Y
Sbjct: 360 EFLFKKVIYHLASEFPNPDHDNDVNAYRE-APPTPAKNRY 398


>UniRef50_Q6PUP4 Cluster: Innexin Vnx-b17; n=1; Hyposoter fugitivus
           ichnovirus|Rep: Innexin Vnx-b17 - Hyposoter fugitivus
           ichnovirus
          Length = 357

 Score =  210 bits (514), Expect = 3e-53
 Identities = 115/357 (32%), Positives = 193/357 (54%), Gaps = 15/357 (4%)

Query: 6   LVSSVAGFVKVRYLIDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGA 65
           L+++V G +K    +    IDN+ FR+HY+ T  IL    +LVT+    G+ I C     
Sbjct: 4   LINAVKGLIK----LPTVSIDNVFFRLHYQFTVIILIAFSLLVTSRQYFGKLIDCHFPDY 59

Query: 66  NPGHVINTFCWITYTF-----TMPNTTSKTAAHPGLGDDNDEKRI--HSYYQWVPFMLFF 118
             G  +N FC +  T+     T  +  S  + H  +   N ++ I  + YYQWV  +LF 
Sbjct: 60  PYGS-LNDFCSVQPTYLEVIGTTHDVISPISPHQ-VRTSNQQREIKYYGYYQWVFIVLFI 117

Query: 119 QGLLFYIPHWIWKNWEEGKVRLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYS 178
           Q + F IP +IWK  E GK++ ++  +     S  +    + + L+ Y    LH  N+Y+
Sbjct: 118 QAVFFSIPQYIWKVCEGGKMKTLAHDLTSPFLS-KECITEKVDHLMDYFFMQLHAQNSYA 176

Query: 179 FGYFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSN-MNQEQRTDPMIEVFPRIT 237
           + YF CE+LNF NVV  I F++ F+G  FL YG  V  F+        T+PM  VFP IT
Sbjct: 177 YKYFGCELLNFVNVVAQICFMNAFIGEDFLLYGIYVTFFNQEAAHPNMTNPMKRVFPTIT 236

Query: 238 KCTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLP 297
           +CTFHK+G SG+++ ++ LC+L  N++NEK            +++SG+ ++Y  A+   P
Sbjct: 237 RCTFHKYGPSGSLENYEGLCILPENVVNEKIYIFLWFWFYVLAIISGIVVLYRIALLASP 296

Query: 298 STRETILKRRFRFGTPNGVEALVRKTQVGDFLLLHLLGQNMSLRVFGEVLDELSRRL 354
           + R  + ++      P+ V+ +  + Q+GD+LL+H L +N +  ++ E++  ++ R+
Sbjct: 297 ALRLYMFRKTCLMNFPDDVQLVHEQLQIGDWLLVHGLWKNTNPMIYKELITRIAHRI 353


>UniRef50_UPI0000D572E5 Cluster: PREDICTED: similar to Innexin inx7
           (Innexin-7) (Gap junction protein prp7) (Pas-related
           protein 7); n=3; Tribolium castaneum|Rep: PREDICTED:
           similar to Innexin inx7 (Innexin-7) (Gap junction
           protein prp7) (Pas-related protein 7) - Tribolium
           castaneum
          Length = 693

 Score =  206 bits (504), Expect = 6e-52
 Identities = 127/373 (34%), Positives = 192/373 (51%), Gaps = 36/373 (9%)

Query: 15  KVRYLIDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGH---VI 71
           +++  +    IDN VF++HYR T+ I F+  ILVT+   IGE I C+SD  N      VI
Sbjct: 11  RIKPKLGSPCIDNWVFKLHYRATTVIFFVATILVTSREYIGEHIKCVSDSVNNKEFHKVI 70

Query: 72  NTFCWITYTFTMP----NTTSKTAAHPGLGD----DNDEKRIHSYYQWVPFMLFFQGLLF 123
            +FC+ + TFT+     N       HPG+           R H YYQWVPF+LF QG++F
Sbjct: 71  ESFCFFSTTFTVIRDEFNFGFGDPPHPGVFPYGLLSKPPIRKHLYYQWVPFVLFGQGVMF 130

Query: 124 YIPHWIWKNWEEGKVRLISEGMRGTMASIADD-----------KNNRQ---NRLVQYLLD 169
            + H++WK+WE G+VR +  G+  +  +  ++           K  ++    R+     +
Sbjct: 131 MLTHFLWKSWEMGRVRKLVSGLTYSSLAFLENSVMVDGKSIPSKKEKEITIRRIKDSFFE 190

Query: 170 TLHMHNTYSFGYFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPM 229
            + ++  ++     CE+LNFANV    +  + FLGG F T G  +         Q    +
Sbjct: 191 NVKINRAWAPQLILCEILNFANVGLQAYITNKFLGGHFYTLGIKIFT-------QGHSIL 243

Query: 230 IEVFPRITKCTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVY 289
            +VFP++TKCTFHK+G SGT+Q HDALC++ALNI+NEK             V+SGL LV+
Sbjct: 244 DDVFPKVTKCTFHKYGPSGTVQLHDALCIMALNIINEKIYIFLWFWFIFLLVLSGLVLVW 303

Query: 290 SAAVCLLPSTRETILKRRFRFGTPN----GVEALVRKTQVGDFLLLHLLGQNMSLRVFGE 345
             A  LL S      +  F FG        ++ + RK    D+L L  L +N+   VF E
Sbjct: 304 RFASILLYSKSPVFGRIIFGFGAKKLSFWKLKTVTRKFTYADWLFLKYLSKNLDGLVFRE 363

Query: 346 VLDELSRRLNLGS 358
           +   +  +L+ G+
Sbjct: 364 LFGRIYEQLDDGA 376


>UniRef50_A2Q0G0 Cluster: Viral innexin-c3.1; n=1; Hyposoter
           fugitivus ichnovirus|Rep: Viral innexin-c3.1 - Hyposoter
           fugitivus ichnovirus
          Length = 361

 Score =  204 bits (497), Expect = 4e-51
 Identities = 110/346 (31%), Positives = 175/346 (50%), Gaps = 11/346 (3%)

Query: 20  IDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHVINTFCWITY 79
           +D   ID   FR+HY+ T  +L +  +L  +    GEP+ C     + G  +N +C +  
Sbjct: 15  LDGTAIDTTFFRLHYKSTVGLLLIFSLLSHSREYFGEPLDCHFTENSLGS-LNKYCAVQS 73

Query: 80  TFTMP--------NTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK 131
           TF +         +TT K   HP   D++ EKR +SYYQWV   L  Q L FY P +IW+
Sbjct: 74  TFVIEPSVKAKNSSTTVKDMMHPA-PDESREKRYYSYYQWVSVALLIQALFFYAPWYIWE 132

Query: 132 NWEEGKVRLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYSFGYFFCEVLNFAN 191
             ++G++  +   M   +    D    +   L+ Y++  +H HN Y++ YF CE+L+  N
Sbjct: 133 TLDKGRMATLIADMAAPILR-KDVIIEKTQSLLDYVIMNMHKHNFYAYSYFACELLSLLN 191

Query: 192 VVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFGASGTIQ 251
           VVG+I  ++ FLG     YG  V  F++   E   DPM  VFP +TKCTF K+  SG +Q
Sbjct: 192 VVGHIILMNIFLGEGLQLYGAFVTAFNDRANEDARDPMETVFPSVTKCTFRKYDGSGDLQ 251

Query: 252 KHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPSTRETILKRRFRFG 311
             +  C+L  N  N K            +V+S + + Y  AV  +PS R  + +      
Sbjct: 252 TFNGFCILTQNSGNAKIYTFLWLWFHLVAVISVITVTYRMAVVFVPSFRLYMFRWSSPLN 311

Query: 312 TPNGVEALVRKTQVGDFLLLHLLGQNMSLRVFGEVLDELSRRLNLG 357
           T   +E + R+   GD+ +L L+G  ++  ++  ++ EL+ RL +G
Sbjct: 312 TSRDIEIVYRELCYGDWFVLRLVGITVNPIIYKTLISELASRLKVG 357


>UniRef50_Q6Q2K8 Cluster: Innexin Vnx-d5.2; n=3; Ichnovirus|Rep:
           Innexin Vnx-d5.2 - Hyposoter fugitivus ichnovirus
          Length = 378

 Score =  201 bits (491), Expect = 2e-50
 Identities = 109/361 (30%), Positives = 184/361 (50%), Gaps = 15/361 (4%)

Query: 1   MAVFGLVSSVAGFVKVRYLIDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIAC 60
           M++  L S + G  +V+ +     IDNM+FR+HYR+T  IL +  +      L  +PI C
Sbjct: 2   MSLVDLKSLLCGLFEVQTI----TIDNMLFRLHYRVTVTILAIFTLFTALRQLFMDPIDC 57

Query: 61  ISDG-ANPGHVINTFCWITYTFT----MPNTTSKTAAHPGLGDDN--DEKRIHSYYQWVP 113
              G + P H  NT+C+I  TF     + +  +KT   PG   D   D+ +++SYYQW+ 
Sbjct: 58  DFVGLSRPFH--NTYCYIHPTFLVERMLTDELNKTVPFPGFSGDTAEDKLKVYSYYQWIS 115

Query: 114 FMLFFQGLLFYIPHWIWKNWEEGKVRLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHM 173
            +L  +  L YIPH+IWK WE GK++ ++  +   + S  D  N R   LV YL   LH 
Sbjct: 116 IVLVLKATLLYIPHYIWKCWEGGKIQSLAGELDVAVLS-EDTLNRRVTSLVDYLFSQLHS 174

Query: 174 HNTYSFGYFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFS-NMNQEQRTDPMIEV 232
           HN Y++ Y  CE+LN   +V  I+ ++ F+G  F  YG +V+ F+    +E R +PM  +
Sbjct: 175 HNRYAYQYMTCELLNVITIVAQIWLMNVFIGKDFHLYGIEVIAFNQQQGKESRLNPMERL 234

Query: 233 FPRITKCTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAA 292
           FP IT CT+ K   +G ++  + +C+L  N  N+K            + +     ++   
Sbjct: 235 FPTITMCTYKKNVTNGIVENINGICLLTQNSANQKMFVFLWFWYHILATIGVFYTIFRIT 294

Query: 293 VCLLPSTRETILKRRFRFGTPNGVEALVRKTQVGDFLLLHLLGQNMSLRVFGEVLDELSR 352
                S R    +   +   P  ++ + +   +GD+ LL +L  N++   + E++  +++
Sbjct: 295 TLFSSSLRYYEFRSNSKKNIPYDIDVVYQNLWIGDWFLLKMLRMNLNTLAYKELISLMAQ 354

Query: 353 R 353
           R
Sbjct: 355 R 355


>UniRef50_UPI00015B5AB8 Cluster: PREDICTED: similar to gap junction
           protein prp33; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to gap junction protein prp33 - Nasonia
           vitripennis
          Length = 367

 Score =  194 bits (472), Expect = 4e-48
 Identities = 118/344 (34%), Positives = 167/344 (48%), Gaps = 33/344 (9%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHVINTFCWITYTFT--- 82
           DN VFR+H R+T  +L  C IL++A   +GEPI CI+ G+     +N +CWI  TFT   
Sbjct: 23  DNFVFRLHSRLTVLLLTGCAILISAKQFVGEPITCITHGSK-AEPVNAYCWIYSTFTVRR 81

Query: 83  -MPNTTSKTAAHPGLGD--DNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKNWEEGKVR 139
            +     +    PG+    + DE   H YYQWV  +L  Q L FY P  +W++WE G ++
Sbjct: 82  HLRGIPGREVVAPGVAQAREGDEILQHRYYQWVCLVLVLQALAFYTPRALWRSWEAGLIQ 141

Query: 140 LISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYSFGYFFCEVLNFANVVGNIFFL 199
            +S G+      I     NR  R  Q        +N Y+  +F CE+LNF N +  ++ L
Sbjct: 142 ELS-GIESRDKIIDYFVENRSIRRAQ--------NNLYALKFFCCEILNFLNTLSQMYLL 192

Query: 200 DTFLGGAFLTYGTDVVR------------FSNMNQEQRTDPMIEVFPRITKCTFHKFGAS 247
           D FL G F  YG  V+             F+N   +Q+ +PM  +FP++ KCT H FG  
Sbjct: 193 DAFLEGQFRHYGPAVISSALTSTNAPKGGFTNPLLQQQVNPMARLFPKLAKCTLHTFGPG 252

Query: 248 GTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPSTRETILKRR 307
           G+ Q HDALCVL LN++NEK            ++   LAL Y   V   P  R  +L+  
Sbjct: 253 GSSQTHDALCVLPLNVVNEKIFVFLWFWLVFLAIAGALALFYRVTVLSQPWARRILLRAS 312

Query: 308 FRFGTPNGVEALVRKTQ---VGD-FLLLHLLGQNMSLRVFGEVL 347
            R G  N     ++       GD F+L  L    + LR   + L
Sbjct: 313 AR-GLSNATITSLQLNHFLGFGDWFVLRRLAADPLILRALADAL 355


>UniRef50_Q8JV08 Cluster: Innexin-like protein 1; n=2; Campoletis
           sonorensis ichnovirus|Rep: Innexin-like protein 1 -
           Campoletis sonorensis virus (CSV)
          Length = 369

 Score =  188 bits (458), Expect = 2e-46
 Identities = 96/283 (33%), Positives = 148/283 (52%), Gaps = 10/283 (3%)

Query: 25  IDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHVINTFCWITYTFTMP 84
           IDN  F +HY+IT  IL    +LVT+      P+ C       G   + +C++  TF   
Sbjct: 19  IDNNFFILHYKITVVILLALAMLVTSQQFFKNPMECNFSDLPLGS--SHYCYVHATFLEQ 76

Query: 85  NTTSKTAAH---PG--LGDDNDEK--RIHSYYQWVPFMLFFQGLLFYIPHWIWKNWEEGK 137
              +        PG  +  +  EK  R ++YY+WV   L  Q +LFY+PH+IWK WE GK
Sbjct: 77  QQITHHVPPQRLPGGNISGETGEKEFRFYNYYEWVYLTLAVQAILFYVPHYIWKAWEGGK 136

Query: 138 VRLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYSFGYFFCEVLNFANVVGNIF 197
           +++++      + S  D   N+   +V+Y   TLH HN Y++ YF CE LN  NVVG I 
Sbjct: 137 MKMLAVEFASPVLS-EDFIENKMIPVVEYFCTTLHSHNAYAYKYFTCEFLNLVNVVGQIL 195

Query: 198 FLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFGASGTIQKHDALC 257
           FL  FLG  F ++G DV+ F +  ++   +P+  +FP +T+C++HK+G SG ++  + LC
Sbjct: 196 FLKIFLGEEFASFGIDVITFDHRQEKSMKNPIDRLFPIVTRCSYHKYGPSGKVENWEGLC 255

Query: 258 VLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPSTR 300
           +L  N LN K            + +S + ++Y       PS R
Sbjct: 256 LLPENSLNGKIYIFMWFWFHMLTAISSVVVIYRIVTLCSPSVR 298


>UniRef50_Q80KH3 Cluster: Innexin Vnx-d1; n=1; Campoletis sonorensis
           ichnovirus|Rep: Innexin Vnx-d1 - Campoletis sonorensis
           virus (CSV)
          Length = 362

 Score =  187 bits (455), Expect = 5e-46
 Identities = 114/346 (32%), Positives = 174/346 (50%), Gaps = 16/346 (4%)

Query: 20  IDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHVINTFCWITY 79
           I    ID+ VFR+HY++T AIL    ILV      GEP+ C           NT+C++  
Sbjct: 15  IHSVQIDSYVFRLHYKVTLAILSAFSILVAPGTFFGEPVDCWFHDFTY-KAFNTWCYVHS 73

Query: 80  TFTMPNTTSKTAA------HPGL----GDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWI 129
           TF++               HP        + DE R   YY+WV   L  Q +  YIPH I
Sbjct: 74  TFSVVRAADHDTRDDADPKHPYAVFLTRTEKDEVRFVDYYRWVCLSLTIQAICCYIPHHI 133

Query: 130 WKNWEEGKVRLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYSFGYFFCEVLNF 189
           WK  E GK++ ++ G+   + S    KN +   LV+YL  TLH H+ Y +  F CE LN 
Sbjct: 134 WKILEGGKMKALTVGLDSLIVSKDCIKNVQL--LVEYLQKTLHSHDHYFYKQFLCESLNV 191

Query: 190 ANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFGA-SG 248
            N+V  I F+++FLG  F  YG +V+ F N+ +    DP   +FP  TKC ++K+ + SG
Sbjct: 192 INIVAQIAFMNSFLGSDFALYGINVLSF-NLTKGPSNDPAARLFPTRTKCVYYKYTSYSG 250

Query: 249 TIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPSTRETILKRRF 308
            ++  + +CVL+ N +N K            +++  + +VY     +  S R   + R  
Sbjct: 251 ELKSVEGICVLSQNPINAKIYCFLWFWFHGMAIIGAIVVVYRITEIISASIRLRAI-RSS 309

Query: 309 RFGTPNGVEALVRKTQVGDFLLLHLLGQNMSLRVFGEVLDELSRRL 354
               PN +  + RK QVGD+ LL  L +N+S  V+ E++  +++RL
Sbjct: 310 SCTDPNDIYVVNRKLQVGDWFLLKNLKRNISPEVYDELIIRIAKRL 355


>UniRef50_Q6RXK5 Cluster: Innexin-like protein 4; n=7;
           Ichnovirus|Rep: Innexin-like protein 4 - Hyposoter
           didymator virus
          Length = 393

 Score =  185 bits (451), Expect = 2e-45
 Identities = 108/328 (32%), Positives = 166/328 (50%), Gaps = 10/328 (3%)

Query: 25  IDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHVINTFCWITYTFTMP 84
           IDN+VF +HY+ T   L    ILV +    GEPI C   G   G + N +C++  TF   
Sbjct: 19  IDNIVFYLHYKPTVTFLIGFSILVASRQYFGEPIDCQFPGYPHGELDN-YCYVQATFARE 77

Query: 85  NTTSKTAAHPGLGDDNDEK-RIHSYYQWVPFMLFFQGLLFYIPHWIWKNWEEGKVRLISE 143
            T ++     G G   +E  R  SYY WV   LF Q + FYIP ++WK WE G+V+L++ 
Sbjct: 78  QTGTRR----GSGHAEEENVRFFSYYSWVFIALFAQAVFFYIPRYMWKGWEGGRVKLLAI 133

Query: 144 GMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYSFGYFFCEVLNFANVVGNIFFLDTFL 203
           G    + S  D    +  RL +Y    LH HN Y++ YFFCE+LN  N+   + FL+ F+
Sbjct: 134 GAECPILS-EDCIEKQTRRLSKYFTMHLHTHNYYAYKYFFCELLNLINIGCQMIFLNRFI 192

Query: 204 GGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFGASGTIQKHDALCVLALNI 263
           G  + +YG DV+ F     E     + E+FP  T C F K+G +G  +K + +C+L  N 
Sbjct: 193 GEGYQSYGIDVI-FP--KHENEGHGIRELFPINTICIFEKYGLTGKKEKLEGICLLTHNP 249

Query: 264 LNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPSTRETILKRRFRFGTPNGVEALVRKT 323
            N+              +V+ + ++Y     L    R  + +        + V A   K 
Sbjct: 250 FNKVIYGFLWFWMQFLVIVTIMVMLYRITTLLSSCFRFYVFRYSTTMNRADEVRAAFNKL 309

Query: 324 QVGDFLLLHLLGQNMSLRVFGEVLDELS 351
           Q+GD+ +L LL +N++  VF +++ EL+
Sbjct: 310 QIGDWFILILLEKNVNREVFKQLITELA 337


>UniRef50_Q9VRX6 Cluster: Innexin inx4; n=2; Sophophora|Rep: Innexin
           inx4 - Drosophila melanogaster (Fruit fly)
          Length = 367

 Score =  174 bits (424), Expect = 3e-42
 Identities = 108/358 (30%), Positives = 168/358 (46%), Gaps = 14/358 (3%)

Query: 17  RYLIDKAV-IDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHVINTFC 75
           +YL  K+V I + +F +H ++T A+L  C  L+++    G+PI C  D       ++ FC
Sbjct: 10  KYLQFKSVHIYDAIFTLHSKVTVALLLACTFLLSSKQYFGDPIQCFGD--KDMDYVHAFC 67

Query: 76  WITYTFTMPNTTSKTAAHPGLGDDND--------EKRIH-SYYQWVPFMLFFQGLLFYIP 126
           WI   +   N T     +       D        E R + +YYQWV  +L  +  +FY+P
Sbjct: 68  WIYGAYVSDNVTVTPLRNGAAQCRPDAVSKVVPPENRNYITYYQWVVLVLLLESFVFYMP 127

Query: 127 HWIWKNWEEGKVRLISEGMRGTMASIADDKNNRQNRLVQYLL-DTLHMHNTYSFGYFFCE 185
            ++WK WE G+++ + +     MA   D        LV Y   D    H  Y   Y FCE
Sbjct: 128 AFLWKIWEGGRLKHLCDDFH-KMAVCKDKSRTHLRVLVNYFSSDYKETHFRYFVSYVFCE 186

Query: 186 VLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFG 245
           +LN +  + N   LD F GG +  Y   ++   N +  Q     + VFP+  KC  +K G
Sbjct: 187 ILNLSISILNFLLLDVFFGGFWGRYRNALLSLYNGDYNQWNIITMAVFPKCAKCEMYKGG 246

Query: 246 ASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPSTRETILK 305
            SG+   +D LC+L LNILNEK            +++  L  +Y  A  L P  R  +L+
Sbjct: 247 PSGSSNIYDYLCLLPLNILNEKIFAFLWIWFILVAMLISLKFLYRLATVLYPGMRLQLLR 306

Query: 306 RRFRFGTPNGVEALVRKTQVGDFLLLHLLGQNMSLRVFGEVLDELSRRLNLGSHAPSA 363
            R RF     ++  +R    GD+ +L  +G N+S  +F ++L+EL    +L    P A
Sbjct: 307 ARARFMPKKHLQVALRNCSFGDWFVLMRVGNNISPELFRKLLEELYEAQSLIKIPPGA 364


>UniRef50_Q7Q5R9 Cluster: ENSANGP00000020577; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000020577 - Anopheles gambiae
           str. PEST
          Length = 386

 Score =  170 bits (413), Expect = 6e-41
 Identities = 110/366 (30%), Positives = 172/366 (46%), Gaps = 12/366 (3%)

Query: 27  NMVFRMHYRITSAILFLCCILVTANNLIGEPIAC-ISDGANPGHVINTFCWI--TYTFTM 83
           ++V+R+H R+T  +L L  +L++A    G PI C I  G      +N FCWI  TY    
Sbjct: 21  DLVWRLHCRVTVFLLLLASLLLSARQYFGNPIDCVIGSGTVSSSTMNEFCWIMGTYISND 80

Query: 84  PN----TTSKTAAHPGLGD-DNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKNWEEGKV 138
           PN    +T     +  +G     E+    YYQWV F+L  Q  +F +P+++WK WE G++
Sbjct: 81  PNFVLDSTDLVKINAKIGHIPESERSYQKYYQWVVFILALQACMFSVPNFLWKAWEAGRL 140

Query: 139 RLISEGMRGTMASIADD-KNNRQNRLVQYL-LDTLHMHNTYSFGYFFCEVLNFANVVGNI 196
           + + +G+  T   + D  +  R+ +L+ YL  D   +H TY   Y FC +LNF NV+ NI
Sbjct: 141 QSLCDGL--TTPIVPDHWEKTRKKQLITYLSADFPRLHRTYLLRYCFCTLLNFCNVLLNI 198

Query: 197 FFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFGASGTIQKHDAL 256
           F ++    G +  Y   V    + +         +VFP+I KC FH  G SG+ Q  D L
Sbjct: 199 FLVNVIFSGFWSNYHPAVKALLSFDFPSWNRYNSQVFPKIAKCDFHFVGPSGSKQNRDGL 258

Query: 257 CVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPSTRETILKRRFRFGTPNGV 316
           C+L LN++NEK             V+S L L++   V      R  +L         + V
Sbjct: 259 CLLPLNVVNEKIFAFIWLWFLGLLVISMLNLLFWIVVLCSKGFRLWLLTAPLYPIRTSYV 318

Query: 317 EALVRKTQVGDFLLLHLLGQNMSLRVFGEVLDELSRRLNLGSHAPSAPSTLEMAPIYPDI 376
              +    VG + LL+ L +N++  V  E++  +S+      H             Y D 
Sbjct: 319 ARALDGQGVGQWFLLYQLCRNLNPIVGRELVQSVSKAKGHNGHKTFRMPKGGEPDFYTDP 378

Query: 377 DKYSKE 382
           + Y +E
Sbjct: 379 EGYDEE 384


>UniRef50_Q174Z8 Cluster: Innexin; n=1; Aedes aegypti|Rep: Innexin -
           Aedes aegypti (Yellowfever mosquito)
          Length = 389

 Score =  166 bits (404), Expect = 7e-40
 Identities = 102/334 (30%), Positives = 167/334 (50%), Gaps = 8/334 (2%)

Query: 27  NMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHV-INTFCWI--TYTFTM 83
           N V+R+H RIT  +L    IL++A +  GEPI CIS  A      +++FCW   TY    
Sbjct: 21  NTVWRLHSRITVYMLVFFTILLSARSYFGEPIECISSAAPTVRASLHSFCWTLGTYISRD 80

Query: 84  PNTTSKT----AAHPGLGDDNDEKRIHS-YYQWVPFMLFFQGLLFYIPHWIWKNWEEGKV 138
           PN    +         +G    E+R++  YYQWVPF+L  Q  LF  P  +W+  E G++
Sbjct: 81  PNFVEASWDIIEIGTHMGHIPKEERLYQKYYQWVPFLLAIQAFLFSFPKHLWRFCERGRL 140

Query: 139 RLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYSFGYFFCEVLNFANVVGNIFF 198
             +   +   ++  A  +  +   L+    ++   HN Y+  +  CE+LNF  V+ N+F 
Sbjct: 141 ETLCHNLTSILSPGAWTRKRKALTLLYLTQESRKGHNKYALIFIGCEILNFFIVLLNMFL 200

Query: 199 LDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFGASGTIQKHDALCV 258
           ++   GG + +Y   +    +++    T     VFP++ KC F   G SG+ Q  DALC+
Sbjct: 201 MNFLFGGFWASYQPAIQALLSLDMNAWTSYNSLVFPKLAKCDFSYIGPSGSKQNFDALCL 260

Query: 259 LALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPSTRETILKRRFRFGTPNGVEA 318
           L  NI+NEK            +VVSG+ L Y  A     S R  +L       + + ++ 
Sbjct: 261 LPQNIVNEKIFAFLWLWFIVLAVVSGVQLCYRLAQLSCRSVRFQLLFSLLDPISYHRLKR 320

Query: 319 LVRKTQVGDFLLLHLLGQNMSLRVFGEVLDELSR 352
           +VR+  +G + LL+ + +N++  V  E++ +LSR
Sbjct: 321 VVREANIGYWFLLYQMARNINKGVMREIIRDLSR 354


>UniRef50_Q9VR82 Cluster: Innexin inx6; n=4; Sophophora|Rep: Innexin
           inx6 - Drosophila melanogaster (Fruit fly)
          Length = 481

 Score =  115 bits (276), Expect = 2e-24
 Identities = 71/254 (27%), Positives = 116/254 (45%), Gaps = 1/254 (0%)

Query: 103 KRIH-SYYQWVPFMLFFQGLLFYIPHWIWKNWEEGKVRLISEGMRGTMASIADDKNNRQN 161
           KR++  YYQWV  +L FQ LLFY P ++WK WE  ++  +   +   +   A  +   Q 
Sbjct: 137 KRMYLRYYQWVFMILLFQSLLFYFPSFLWKVWEGQRMEQLCCEVGDALIVEATYRTRLQM 196

Query: 162 RLVQYLLDTLHMHNTYSFGYFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMN 221
               +      +H  YS  Y FCE+LN    + N + +D    G +  Y   +      +
Sbjct: 197 LTRYFRAQFAPIHWCYSIKYAFCELLNVFISILNFWLMDVVFNGFWYKYIHALAAIPVYD 256

Query: 222 QEQRTDPMIEVFPRITKCTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSV 281
                     VFP++ KC    +G SGT    D LCVL LNILNEK            ++
Sbjct: 257 WNLWNLMTSRVFPKVAKCEMFVYGPSGTPNIMDILCVLPLNILNEKIFAVLYVWFLFIAL 316

Query: 282 VSGLALVYSAAVCLLPSTRETILKRRFRFGTPNGVEALVRKTQVGDFLLLHLLGQNMSLR 341
           ++ + ++Y   V   P  R  +L+        + V  ++     GD+ +L  +  N++  
Sbjct: 317 LAIMNILYRLLVICCPELRLQLLRTHLNGMPKSHVREVLASAGYGDWFVLMCVSINVNPT 376

Query: 342 VFGEVLDELSRRLN 355
           +F E+L++L  +LN
Sbjct: 377 LFRELLEQLYAKLN 390



 Score = 47.2 bits (107), Expect = 7e-04
 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 2/68 (2%)

Query: 18 YLIDKAV-IDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHVINTFCW 76
          YL  K V I + +F +H + T  IL  C  L++A    GEPI C+S      +V  ++CW
Sbjct: 11 YLRLKTVRIYDPIFTLHSKCTIVILLTCTFLLSAKQYFGEPILCLSSERQADYV-QSYCW 69

Query: 77 ITYTFTMP 84
             T+ +P
Sbjct: 70 TMGTYILP 77


>UniRef50_Q8B637 Cluster: Viral innexin; n=3; Ichnovirus|Rep: Viral
           innexin - Hyposoter didymator virus
          Length = 363

 Score =  111 bits (266), Expect = 4e-23
 Identities = 91/349 (26%), Positives = 155/349 (44%), Gaps = 13/349 (3%)

Query: 10  VAGFVKVRYLIDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGH 69
           V G +  R      V D+  FR++YRIT  +L     L+    +  +P+ C       G 
Sbjct: 4   VFGAIFGRCSRQSVVTDSAFFRLNYRITVILLVASAWLLFVLEIFLDPMECTFADYPKGD 63

Query: 70  VINTFCWITYTFTMPN--TTSKTAAHP--GLGDDNDEKRIHSYYQWVPFMLFFQGLLFYI 125
             N++C +   FT+    T  +  +H            R+ +YYQ     L  Q +LFYI
Sbjct: 64  -FNSYCSLKSIFTLRRKVTLKEHVSHVEGSAVPAYVGVRVFTYYQLCSITLLLQAVLFYI 122

Query: 126 PHWIWKNWEEGKVRLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYSFGYFFCE 185
           P  +WK  E GK+++++  +  T     D +      L  Y  + LH H+ Y+FGY  CE
Sbjct: 123 PRCVWKWLEGGKMKMLATELI-TPIKGGDCERKDIQPLTSYFRENLHKHDRYAFGYMICE 181

Query: 186 VLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTF-HKF 244
           +LN  N+   +  L+ F G +F    +DV           TD   +     T+CT+   F
Sbjct: 182 LLNVFNLGVQLQLLNHFTGKSF--EFSDVYAIFTAQPTGVTDMTGQTLSMTTECTYPGPF 239

Query: 245 GASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPSTRETIL 304
             +G       +C L  N  N++            +    L ++Y  A C++   R   L
Sbjct: 240 NDTGNPGDITGICELVPNSYNDQIQVFLWLWMYLLNAFGVLVILYRFATCVISLLR--WL 297

Query: 305 KRRFR-FGTPNGVEALV-RKTQVGDFLLLHLLGQNMSLRVFGEVLDELS 351
           K R   +  P+G +A+V  + ++GD+ +L +L QN+   ++ E++ +L+
Sbjct: 298 KFRVSVWIIPDGSQAVVFERLKIGDWFVLTMLRQNIREVLYVELITQLA 346


>UniRef50_Q17394 Cluster: Transmembrane protein; n=3;
           Caenorhabditis|Rep: Transmembrane protein -
           Caenorhabditis elegans
          Length = 428

 Score =  109 bits (261), Expect = 2e-22
 Identities = 84/309 (27%), Positives = 136/309 (44%), Gaps = 32/309 (10%)

Query: 24  VIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPG---HVINTFCWITYT 80
           V D+ V +++Y  TSAI+F   I+V+A   +G PI C                +CW+  T
Sbjct: 17  VDDDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENT 76

Query: 81  FTMPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK---NWEEG- 136
           + +P     T+A P    D   ++I SYYQWVPF+L  + L FYIP  +W+   +W  G 
Sbjct: 77  YYLP----LTSAFPLEYGDRRARQI-SYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGI 131

Query: 137 KVRLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMH----------------NTYSFG 180
            V+ +++         AD +      +  ++ D L +                 N  +  
Sbjct: 132 NVQSLTQMACDARMMDADARAATVQTIAGHMEDALEIQREVTDVSGMCVQKRWANYVTLL 191

Query: 181 YFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCT 240
           Y F ++L   NVV  +F L++FLG   L YG  ++R     +E         FPR+T C 
Sbjct: 192 YVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGN---FPRVTMCD 248

Query: 241 FHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPSTR 300
           F +    G +  H   CVL +N+ NEK            + VS +++ +   +  LP   
Sbjct: 249 F-EVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQH 307

Query: 301 ETILKRRFR 309
              +++  R
Sbjct: 308 MKFIRKYLR 316


>UniRef50_Q8I6U1 Cluster: Innexin 2; n=2; Hirudo medicinalis|Rep:
           Innexin 2 - Hirudo medicinalis (Medicinal leech)
          Length = 398

 Score = 99.5 bits (237), Expect = 1e-19
 Identities = 78/277 (28%), Positives = 128/277 (46%), Gaps = 44/277 (15%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDG---ANPGHVINTFCWITYTFT 82
           D+   R+ Y+ T  +  L  I+++    +G+PI C        N     N +CWI  T+ 
Sbjct: 20  DDFADRLVYKTTVGMFILFAIVISTKQYVGDPIQCWVPAEFTGNQEEYTNNYCWIKNTYY 79

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK--NWEEG-KVR 139
           +P   +    H     + ++++I  YYQW P +L  Q L+ Y+P  +W+  N + G  V 
Sbjct: 80  LPYEKNIPKEH-----EAEKRKIIPYYQWAPLILGVQALICYLPIILWRYLNKKSGIDVN 134

Query: 140 LISE-GMRGTMASIADDKNNRQNRLV----QYLLD--------TLHMHNTYSFG------ 180
            I E G + T A  A++++   N +     +YL +        TL + + +S        
Sbjct: 135 AIVEAGEKFTNAEAAENRDKTLNFMTKLMDRYLANQRDVPTGCTLSLKHVFSRTCFKWCG 194

Query: 181 ----------YFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMI 230
                     Y F + L   +V+G +F L+ FLG  F  YG D +R   M ++Q      
Sbjct: 195 RKRGNYLTTLYLFSKFLLLVSVLGQLFALNFFLGQDFHMYGFDAIRNMFMGEDQAAS--- 251

Query: 231 EVFPRITKCTFHKFGASGTIQKHDALCVLALNILNEK 267
           + FPR+T C F K    G +Q++   CVL +N+ NEK
Sbjct: 252 DRFPRVTMCDF-KVRRLGNVQRYTVQCVLPINLFNEK 287


>UniRef50_Q4VTM8 Cluster: Pannexin 2; n=4; Opisthobranchia|Rep:
           Pannexin 2 - Aplysia californica (California sea hare)
          Length = 416

 Score = 93.9 bits (223), Expect = 6e-18
 Identities = 83/334 (24%), Positives = 139/334 (41%), Gaps = 42/334 (12%)

Query: 7   VSSVAGFVKVRYLIDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGAN 66
           + S+ G V     +  A  D+ + R+++  T  ++ L  I+V+    +G+PI C      
Sbjct: 3   IGSIIGGVPSLKKLQGASNDDWIDRLNHVWTVFLMALFAIVVSTGQFVGDPIHCWCPAEF 62

Query: 67  PGHVIN---TFCWITYTFTMPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLF 123
            G  ++   ++CWI  T+ +P  T     H     DN E    +YYQWVP +L FQ  +F
Sbjct: 63  TGAYVDYAKSYCWIKNTYYIPMDTPIPTDH-----DNRESEELTYYQWVPLILLFQAFMF 117

Query: 124 YIPHWIWKNWEEGK-VRL--ISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYSFG 180
             P+ +W+ +  G  + L  I +    T     +D++   + + +Y+   L  H  Y + 
Sbjct: 118 KFPNILWRLFNGGSGINLDKIVDMAEKTQLGSPEDRDKTIDHISKYMDRWLETHREYHWN 177

Query: 181 -------------YFFC---------------EVLNFANVVGNIFFLDTFLGGAFLTYGT 212
                         FFC               +V+  ANV+   F L+ FL   +  YG 
Sbjct: 178 ALIKAKQTLSRVCCFFCNKRAGTYLTAFYLFIKVVYAANVIAQFFILNAFLSQDYNLYGF 237

Query: 213 DVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFGASGTIQKHDALCVLALNILNEKXXXXX 272
           +V+       E+  +     FPR+T C F K      IQ     CVL +N+ NEK     
Sbjct: 238 EVLNMLGSGSEEWKES--TRFPRVTLCDF-KIRQLQNIQTWTVQCVLPINLFNEKIFIVI 294

Query: 273 XXXXXXXSVVSGLALVYSAAVCLLPSTRETILKR 306
                  + ++ L LV      ++   R T +K+
Sbjct: 295 WFWLVLVATLTCLNLVSWLYRVMVKRNRATYIKK 328


>UniRef50_Q8MXG9 Cluster: Innexin protein 18, isoform a; n=3;
           Caenorhabditis|Rep: Innexin protein 18, isoform a -
           Caenorhabditis elegans
          Length = 436

 Score = 91.1 bits (216), Expect = 4e-17
 Identities = 86/361 (23%), Positives = 151/361 (41%), Gaps = 39/361 (10%)

Query: 20  IDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHV---INTFCW 76
           ++  V D+ V R+HY  TS ++ +  +LV+A   +G PI C         +      +CW
Sbjct: 19  LEPRVDDDFVDRLHYLYTSTMVLMFAVLVSAKQYVGHPIECFVPAQFTRAMEQYTENYCW 78

Query: 77  ITYTFTMPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK--NWE 134
           +  T+ +P         P   DD + ++I  YYQWVPF+L    L F+IP  +W+    +
Sbjct: 79  VQNTYWVPFQD----LIPHRLDDRERRQI-GYYQWVPFVLAVAALTFHIPSSVWRMLAGQ 133

Query: 135 EG-KVRLISEGMRG--TMASIADDKN-----NRQNRLVQYLLD-TLHMHNTYSFGYF--- 182
            G    L+ + + G   +  +  DK         +  + Y  D     H+ Y F  F   
Sbjct: 134 SGLNAGLVLQLVCGDENVDPVVRDKTVDIVARHIDDALMYQRDHGARRHSVYIFAIFKLG 193

Query: 183 ------------FCEVLNFANVVGNIFFLDTFLGGA-FLTYGTDVVRFSNMNQEQRTDPM 229
                       F + L+ ANV+     L++FL  + +  +G  V+    M +E R    
Sbjct: 194 KFYGAYVSSVYIFIKALHLANVILQFMLLNSFLQTSDYPMFGAHVLYDLFMGREWRDSGK 253

Query: 230 IEVFPRITKCTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVY 289
              FPR+T C F +    G + +H   CVL +N+L EK            ++V+ L L++
Sbjct: 254 ---FPRVTLCDF-EIRVLGNVHRHTVQCVLVINMLTEKIFIFLWLWLTVLAIVTALNLIF 309

Query: 290 SAAVCLLPSTRETILKRRFRFGTPNGVEALVRKTQVGDFLLLHLLGQNMSLRVFGEVLDE 349
                +  S RE  + +     +      + R  +     LL ++  +    +  +V ++
Sbjct: 310 WFIALVSNSCREHFVSKHLDIQSDQISRFVHRFLRADGVFLLQMIASHSGNLMAAKVTEQ 369

Query: 350 L 350
           L
Sbjct: 370 L 370


>UniRef50_Q19746 Cluster: Innexin-3; n=2; Caenorhabditis|Rep:
           Innexin-3 - Caenorhabditis elegans
          Length = 420

 Score = 84.6 bits (200), Expect = 4e-15
 Identities = 69/267 (25%), Positives = 114/267 (42%), Gaps = 35/267 (13%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPG---HVINTFCWITYTFT 82
           D+ V R+ Y  T+ +L    I+V+    +G  I C       G        +C+I  TF 
Sbjct: 21  DDAVDRLSYVTTATLLAFFSIMVSCKQYVGSAIQCWMPMEFKGGWEQYAEDYCFIQNTFF 80

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKN-WEEGKV--- 138
           +P  +      PG  +D  +  I  YYQWVP +L  Q  +FY+P WIW + +++  +   
Sbjct: 81  IPERSEI----PGDVEDRQKAEI-GYYQWVPIVLAIQAFMFYLPSWIWSSLYKQCGLDFP 135

Query: 139 RLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYSFGYFFC-------------- 184
            +ISE      +  ++ +    N+LV ++ D L   +   +G F+C              
Sbjct: 136 SVISEA-EALRSQDSETRTKGVNKLVDFIGDILDTRSKNEYGRFYCYRFGKGLGSMTSML 194

Query: 185 ----EVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCT 240
               +++  ANV      L+ FLG     +G          +E +      VFPR+T C 
Sbjct: 195 YICIKLMYLANVFVQFIILNKFLGNETFLWGFHTFADLYAGREWQDSG---VFPRVTLCD 251

Query: 241 FHKFGASGTIQKHDALCVLALNILNEK 267
           F        + ++   CVL +N+ NEK
Sbjct: 252 F-SVRKLANVHRYTVQCVLMINMFNEK 277


>UniRef50_Q38HR7 Cluster: Innexin 4; n=1; Hirudo medicinalis|Rep:
           Innexin 4 - Hirudo medicinalis (Medicinal leech)
          Length = 421

 Score = 84.2 bits (199), Expect = 5e-15
 Identities = 72/278 (25%), Positives = 126/278 (45%), Gaps = 45/278 (16%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISD----GANPGHVINTFCWITYTF 81
           D++  R+  R T A+L    +L++ N  +  PI C +     GA+     N +CW+  T+
Sbjct: 20  DDIADRLSSRYTVALLITFAVLISMNQYVRNPITCWAPVHFTGAHTKFATN-YCWVKNTY 78

Query: 82  TMPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK--NWEEG--- 136
            +P   ++    P      D+K+   YYQW+PF+L FQ +LFY+P  IW   N + G   
Sbjct: 79  YIP-WGNEVPKGP------DDKQTVPYYQWIPFILLFQAILFYLPTQIWHGLNSKSGIDA 131

Query: 137 --------KVRLISEG--MRGTMASIADDK----NNRQNR---------LVQYLLDTL-- 171
                    +  I EG   + TM  +++      +NR  R         ++ Y+   +  
Sbjct: 132 DNILQAAHAISKIGEGEAQKRTMKMLSNQMDRFLSNRTERKGCKLHAKTIMSYMCCFICG 191

Query: 172 -HMHNTYSFGYFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMI 230
             + N     +   ++   AN+   +F L+  L   F ++G D+++ + ++ +  T+   
Sbjct: 192 RRLGNYLIIVFIISKMFYIANIFAQLFVLNKILSIRFDSFGFDLLK-NMVSSDDWTESSA 250

Query: 231 EVFPRITKCTFHKFGAS-GTIQKHDALCVLALNILNEK 267
             FPR+T C F   G      Q +   CVL +N+ NEK
Sbjct: 251 VAFPRVTYCDFAVRGQDLANTQTYTVQCVLPINLYNEK 288


>UniRef50_O61787 Cluster: Innexin-16; n=2; Caenorhabditis|Rep:
           Innexin-16 - Caenorhabditis elegans
          Length = 372

 Score = 82.6 bits (195), Expect = 2e-14
 Identities = 65/250 (26%), Positives = 109/250 (43%), Gaps = 17/250 (6%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPG---HVINTFCWITYTFT 82
           D  + R++Y +T++IL    +L+ A N +GEP+ C +     G       ++C+I  T+ 
Sbjct: 22  DTSIDRLNYVVTTSILIAFSLLLFAKNYVGEPMQCWTPNQFAGGWESFAESYCFIENTYF 81

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKNWEEGK----V 138
           +P   S   A      +  E R   YYQWVPF+L  Q L F +P   W  +         
Sbjct: 82  VPMQDSNLPAA-----ETREGREMIYYQWVPFLLVIQALFFCVPRAFWIIYPSYSGLTIA 136

Query: 139 RLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYSFG-YFFCEVLNFANVVGNIF 197
            +I+   +        D+   Q  ++ +  +    H +  F  Y   ++L   N+V   F
Sbjct: 137 DMITAARQNGKQLEGADEALEQVAMINWRTEQQKGHGSRIFNCYLVMKLLILLNIVLQFF 196

Query: 198 FLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFGASGTIQKHDALC 257
            L++FL  A+  +G  +  F +M   +        FPR++ C  +     G I      C
Sbjct: 197 LLNSFLNTAYTFWGWGI--FWDMVNGRHWQESGH-FPRVSFCDIN-VRELGNIHHWSLQC 252

Query: 258 VLALNILNEK 267
           VL +N+ NEK
Sbjct: 253 VLMVNMFNEK 262


>UniRef50_Q38HR0 Cluster: Innexin 11; n=2; Hirudo medicinalis|Rep:
           Innexin 11 - Hirudo medicinalis (Medicinal leech)
          Length = 420

 Score = 81.4 bits (192), Expect = 4e-14
 Identities = 97/366 (26%), Positives = 145/366 (39%), Gaps = 52/366 (14%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHVINTFCWITYTFTMPN 85
           D+   ++  + T  IL L  IL T    I EPI+C      P H  +     T       
Sbjct: 20  DSFTDQLSCKYTVYILSLVVILSTTRVFIDEPISCYC----PTHFTDNQVEYTKKTCWVM 75

Query: 86  TTSKTAAHPGLGDDNDEK----RIHSYYQWVPFMLFFQGLLFYIPHWIWK---------- 131
            T    AH    +D   K    ++ +YYQW+P  L  Q +LFY P +IWK          
Sbjct: 76  NTQYIEAHEAPRNDPSRKDSAEKLVTYYQWIPLFLTLQAILFYTPRFIWKRLNKKSGIAV 135

Query: 132 -NWEEGKVRLI----SEGMRGTMASIAD-------------DKNNRQNRLVQYLLDTLHM 173
            N  +G +  +    SE  + T+  +A              D N +    + +L  TL  
Sbjct: 136 NNITDGSIDCLRKGDSEESQKTITFLAQYMERFLGWQKQKLDNNFKGKNKLCHLRSTLR- 194

Query: 174 HNTYSFGYFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVF 233
            N     Y   + L  ANV+G IF L+ FLG  F  YG DVV         R       F
Sbjct: 195 GNYLVVVYLAIKALYIANVIGQIFLLNAFLGNDFHMYGIDVVSRLIRRLPWRISYR---F 251

Query: 234 PRITKCTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAV 293
           PRIT+C         T+  H   CVL +N+  E             +  +  + ++    
Sbjct: 252 PRITRCNL-PIRVVDTVHTHKIQCVLPMNLFYEIIFIFIWFWFVFVAAATVGSFIFWLVN 310

Query: 294 CLLPSTRETILKRRFRFG---TPNGVEALVRKTQVGDFL------LLHLLGQNMSLRVFG 344
            +  S +E+ +K+R       T +  E +  KT VGD+L      +L +  +N S  +  
Sbjct: 311 SIRMSVQESYIKQRLLVMEKITKDQREEV--KTFVGDYLKRDGCFVLRMAAKNSSDLIAS 368

Query: 345 EVLDEL 350
           E++ EL
Sbjct: 369 ELICEL 374


>UniRef50_Q23027 Cluster: Innexin-5; n=2; Caenorhabditis|Rep:
           Innexin-5 - Caenorhabditis elegans
          Length = 447

 Score = 81.4 bits (192), Expect = 4e-14
 Identities = 72/310 (23%), Positives = 126/310 (40%), Gaps = 32/310 (10%)

Query: 16  VRYLIDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPG---HVIN 72
           VR     A  +++  R  Y+ TS +L    I++ A+  +G PI C               
Sbjct: 9   VRKFQRSAESNDIADRFSYQYTSTLLGFSAIMMAASQYVGRPIQCWVPAQFTRTWEKYAE 68

Query: 73  TFCWITYTFTMPNTTSKTAAHPGLGDDNDEKRIHS--YYQWVPFMLFFQGLLFYIPHWIW 130
           T+C+I  T+ +P   +          D+         YYQW+P +L  Q  LFY+P  IW
Sbjct: 69  TYCFIKGTYFLPGAFASEGEMSVTSPDDAVTATPQVGYYQWIPIVLVLQAFLFYLPSIIW 128

Query: 131 KNWEEG------KVRLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHN--------- 175
           + + E       ++  +SE  R   ++++DD+  +  +  +Y    L+  N         
Sbjct: 129 RTFNESCELKIKELAAVSEASRKIKSNMSDDQ-VKATKFGRYFFKKLNFRNESPVFKETG 187

Query: 176 -TYSFG------YFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDP 228
              + G      Y   ++L  AN+V   + L  FL      +G    +     +E  T  
Sbjct: 188 SVVASGKFLPALYLLVKILYLANIVLQFWILTYFLETKSWMWGWQTFQDLMAGREWET-- 245

Query: 229 MIEVFPRITKCTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALV 288
              +FPR+T C F     + ++  H   CV+ +N+L EK             +++  +L 
Sbjct: 246 -TGIFPRVTMCDFSIMDLT-SVHDHSIQCVIVINMLAEKVYVFFWFWLLFVGLLTVCSLA 303

Query: 289 YSAAVCLLPS 298
           Y A + +L S
Sbjct: 304 YWAVIYMLQS 313


>UniRef50_O44887 Cluster: Innexin protein 13; n=2;
           Caenorhabditis|Rep: Innexin protein 13 - Caenorhabditis
           elegans
          Length = 385

 Score = 80.2 bits (189), Expect = 8e-14
 Identities = 72/300 (24%), Positives = 120/300 (40%), Gaps = 29/300 (9%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPG---HVINTFCWITYTFT 82
           D+ + R++Y  T  +L +  + ++A   +G+PI C       G        +C++  T+ 
Sbjct: 17  DDSIDRLNYYWTPMLLVIFALTLSAKQYVGQPIQCWIPAQFTGAWEQYSENYCFVQNTYF 76

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK--NWEEG---- 136
           +    S     P    D +   I  YYQWVPF+L  Q +LFY+P   W+  N+  G    
Sbjct: 77  I----SPDKYIPDSEIDREGAEI-GYYQWVPFILGLQAILFYLPSLFWRLMNFNSGVALK 131

Query: 137 -------KVRLISEGMRGTMASIAD----DKNNRQNRLVQYLLDTLHMHNTYSFGYFFCE 185
                  K   + E  R   A        +    Q+R  +Y     +  +  ++ Y F +
Sbjct: 132 KMLFGAKKADRVDEKARNEAAKSTGAHLYESLTLQSRFAKYTSAFTYGGSYLTYLYLFVK 191

Query: 186 VLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFG 245
            L    +V     L+ FLG ++  +G  ++      +E         FPR+T C F +  
Sbjct: 192 FLYLVQIVFQFIILNNFLGTSYTFWGLGILSDILNGREWEESGH---FPRVTMCDF-EVR 247

Query: 246 ASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPSTRETILK 305
             G   +H   CVL +N+ NEK             V + L LV      +  S R+  +K
Sbjct: 248 VLGNKHRHTVQCVLMINMFNEKVYVFLWFWLVIVGVATFLNLVNWTRKLMFRSARKAHIK 307


>UniRef50_Q38HR6 Cluster: Innexin 5; n=1; Hirudo medicinalis|Rep:
           Innexin 5 - Hirudo medicinalis (Medicinal leech)
          Length = 413

 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 74/266 (27%), Positives = 107/266 (40%), Gaps = 30/266 (11%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGH---VINTFCWITYTFT 82
           D+ V R+   +T  +L    I+VT    +GEPI C       G     IN++CWI  T+ 
Sbjct: 21  DDRVDRLSRNVTVTMLVFFSIVVTTKTFVGEPIHCWVPPRFSGSQEDYINSYCWIRNTYF 80

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKNWEE------G 136
           + +       H    D+  ++ I +YYQWVP +L  Q L FY+P+  WK+          
Sbjct: 81  LDHHEDVPLEH----DETPKEEI-TYYQWVPLILLIQALFFYMPYLFWKSCSNKTGLDLN 135

Query: 137 KVRLISEGMRGTMASIADDK--NNRQNRLVQYLLDT---LHMHNTYSFGYFF--CEVLNF 189
            + L  E    T  +   DK       ++ +YL ++        T SF      C  L  
Sbjct: 136 SIVLAGESFNATETAEVRDKTMGYMTTQMDRYLAESRKDFRKSRTISFKQILACCTCLKG 195

Query: 190 ANVVGNIFFLDT-FLGGAFLTYGTDVVRFSN-----MNQEQRTDPMI--EVFPRITKCTF 241
             + G   F+   FL  A L +      F N      +    T  M+    FPR T C F
Sbjct: 196 TCLYGFYMFIKVLFLINALLQFFALTYIFGNGLEIIKSSVNDTGQMMGSRHFPRTTMCDF 255

Query: 242 HKFGASGTIQKHDALCVLALNILNEK 267
            K    G   +    CVL +N  NEK
Sbjct: 256 -KVRRLGNNHRTTVQCVLPINHFNEK 280


>UniRef50_Q2L6M6 Cluster: Innexin9; n=2; Dugesia japonica|Rep:
           Innexin9 - Dugesia japonica (Planarian)
          Length = 439

 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 78/324 (24%), Positives = 148/324 (45%), Gaps = 49/324 (15%)

Query: 25  IDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACI----SDGANPGHVINTFCWITYT 80
           +++   ++++  +  IL +  ++VT  +   +P+AC       G+N  + +  +CW+  T
Sbjct: 21  VEDFADKLNFLFSVVILIISMMVVTVKSYFFKPLACYIATTPSGSNFDNYLENYCWVHGT 80

Query: 81  FT-MPNTT-SKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKNWEEGKV 138
            + +P     +T A   + D    KRI +YYQWVPF+L  Q ++FY+P  IW+     KV
Sbjct: 81  ISILPGENIPQTDADWAIVDQT--KRI-TYYQWVPFILGLQCIMFYVPRVIWQLICYNKV 137

Query: 139 --RLISEGMRGTMASIA--DDKNNRQNRLVQYLLDTLHMHNTYSFG---------YFFCE 185
              L S  +    AS +   ++ ++  R+V+ + D L  H  Y  G         Y  C 
Sbjct: 138 GTNLESLAIDADAASHSPPSERKDKIERIVRTIEDMLFQHRDYRQGKMADMRRNIYKMCN 197

Query: 186 ------------VLNF--------ANVVGNIFFLDTFLG--GAFLTYGTDVVRFSNMNQE 223
                       VL++         NV+G +F +  FLG   +  ++G  ++  SN+  +
Sbjct: 198 FCVFSKHMGTWLVLSYILMKFMYGINVIGQLFLMKKFLGFNSSMSSFGYTIL--SNI-AD 254

Query: 224 QRTDPMIEVFPRITKCTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVS 283
            +      +FPR+T C   +    G   K+   C L +N+LNEK             +++
Sbjct: 255 GKEWHQTGIFPRVTYCYIGEIKHLGASNKYVGQCALPINMLNEKIYVFLWFWVFLVGIIT 314

Query: 284 GLAL-VYSAAVCLLPSTRETILKR 306
            +++ ++   + +L S R + +K+
Sbjct: 315 AISIPMWFFRIAIL-SRRSSFIKK 337


>UniRef50_O61715 Cluster: Innexin protein 19, isoform a; n=3;
           Caenorhabditis|Rep: Innexin protein 19, isoform a -
           Caenorhabditis elegans
          Length = 454

 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 76/308 (24%), Positives = 129/308 (41%), Gaps = 44/308 (14%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIAC-ISDGANPG--HVINTFCWITYTFT 82
           D+ V R++Y  T  IL +CC++++A    G PI C ++  +       I ++CWI  T+ 
Sbjct: 37  DDAVDRLNYYYTPLILAVCCLVISAKQYGGTPIECWVNPHSRESMEEYIESYCWIQNTYW 96

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK--NWEEGK--V 138
           +P   +    H       +EK+I  YYQWVPF+L  + L+F +P   W+  +++ G    
Sbjct: 97  IPMYENVPDDHTA----REEKQI-GYYQWVPFILIAEALMFSLPCIFWRLCSFQSGLNIQ 151

Query: 139 RLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHN------------TYSFGYF---- 182
            LI+    G     A D+      +    +D L + +               F  F    
Sbjct: 152 TLINAACDGQALLDASDRQKAVEAITTNFVDNLDLQSPNGRIRARGWIARIKFSRFLSGQ 211

Query: 183 -------FCEVLNFANVVGNIFFLDTFLGGA-FLTYGTDVVRFSNMNQEQRTDPMIEV-- 232
                  F ++L   NVV     L+  L  + FL +G     F  +N      P  E   
Sbjct: 212 CLSILHSFTKLLYSMNVVAQFLILNACLKSSDFLFFG-----FQVLNDIWAGRPWTETGH 266

Query: 233 FPRITKCTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAA 292
           FPR+T C F +      + ++   C L +NI+NEK            ++++  + +Y  A
Sbjct: 267 FPRVTLCDF-EVRYLANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIA 325

Query: 293 VCLLPSTR 300
              + S +
Sbjct: 326 NSFIHSEK 333


>UniRef50_O61786 Cluster: Innexin protein 15; n=2;
           Caenorhabditis|Rep: Innexin protein 15 - Caenorhabditis
           elegans
          Length = 382

 Score = 77.0 bits (181), Expect = 8e-13
 Identities = 70/266 (26%), Positives = 121/266 (45%), Gaps = 39/266 (14%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPG---HVINTFCWITYTFT 82
           D+ + R++++ ++ +  L  +++  +   G  I+C +     G        +C I  T+ 
Sbjct: 18  DDFIDRLNFQYSAYVFALSALVIGYHTYFGRAISCWTPAEFKGGWNEYTTDYCLIENTYY 77

Query: 83  MPNTTSKTAAHPGLGDDN--DEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK--NWEEG-K 137
           +P         P +  +   +EK + SYYQWV F+L F   LFY+P+  W   NW  G +
Sbjct: 78  VP------LEDPNMPPERYREEKEL-SYYQWVQFILVFLAFLFYLPYLYWSTVNWWSGLQ 130

Query: 138 VRLISE----------GMRGT----MASIADDKNNRQNRLVQY-LLDTLHMHNTYSFGYF 182
           V+ + +          G R      +AS      +RQ R     L+  +   N  SF Y 
Sbjct: 131 VKAVVDVACNLDKTDVGKRNAGIEKIASHLKKYIDRQGRKSPIPLIPNIIGRNWVSFNYI 190

Query: 183 FCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIE-VFPRITKCTF 241
             + L   N++  +F +  FL       G D+  F ++     ++ +   +FPR T C F
Sbjct: 191 LTKFLFLVNLIAQMFLIHFFL-------GFDLDDFISLRVGFGSNWIANGIFPRQTMCDF 243

Query: 242 HKFGASGTIQKHDALCVLALNILNEK 267
            +    G+IQK+   CVL++N+LNEK
Sbjct: 244 -EIRKKGSIQKYSVQCVLSMNMLNEK 268


>UniRef50_Q8T393 Cluster: Innexin; n=1; Chaetopterus
           variopedatus|Rep: Innexin - Chaetopterus variopedatus
           (Parchment worm)
          Length = 399

 Score = 75.8 bits (178), Expect = 2e-12
 Identities = 74/275 (26%), Positives = 119/275 (43%), Gaps = 43/275 (15%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGA---NPGHVINTFCWITYTFT 82
           D++V R++++ T+ IL +  I+V+    +G+PI C        N     N  CW+T T+ 
Sbjct: 21  DDIVDRLNHQYTTFILVIFAIVVSTKQYVGDPIHCWCPAYFTDNHEDFTNKVCWVTNTYY 80

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIH-SYYQWVPFMLFFQGLLFYIPHWIWK---------- 131
           +P    +    P    D  E R H SYYQWVP +L  Q L+FY+P   W+          
Sbjct: 81  LPY---EQRVIP----DVHEPRAHISYYQWVPSILLVQALMFYLPCMTWRFLNNRSGVDL 133

Query: 132 -------------NWEEGKVRLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYS 178
                         +EE + + I   +R         K  ++ RL + L D L  +    
Sbjct: 134 NSIVESALMCQNTAFEESRDKTIRYIVRLLDRYFGAQKQRKKGRLAR-LKDQLGRNAFLV 192

Query: 179 FGYFFCEVLNFANVVGNIFFLDTFLGGAFLT---YGTD--VVRFSNMNQEQRTDPMI--E 231
           F   +   +    ++  I +L   +G  FL     GTD  +  F  +++  + + +I   
Sbjct: 193 FSKRYGNFIVILYIIVKILYLINVVGQLFLLNAFLGTDYHLYGFQIVDKLIKDENIIVSS 252

Query: 232 VFPRITKCTFHKFGASGTIQKHDALCVLALNILNE 266
            FPR+T C F +    G I  H   CVL +N+ NE
Sbjct: 253 RFPRVTMCDF-RIRQLGNIHNHTVQCVLPINMFNE 286


>UniRef50_Q23157 Cluster: Innexin-11; n=2; Caenorhabditis|Rep:
           Innexin-11 - Caenorhabditis elegans
          Length = 465

 Score = 75.8 bits (178), Expect = 2e-12
 Identities = 79/317 (24%), Positives = 127/317 (40%), Gaps = 36/317 (11%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPG---HVINTFCWITYTFT 82
           D+   R++Y +T  IL    +L++     G PI C+     PG        +CW   T+ 
Sbjct: 20  DDWSDRLNYLMTPNILLAFSVLISFKQFGGRPIECMFPNKFPGSWEQYAENYCWSQDTYF 79

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKNW-EEGKVRL- 140
           +  T   +          D +   SYYQWVPF L  Q   F  P ++WK +     +R+ 
Sbjct: 80  VEPTQDVSLLKKEERYTPDRQL--SYYQWVPFFLLLQAAFFRAPSYLWKYFSNHSGIRIH 137

Query: 141 -----------ISEGMRGT--------MASIADDKNNRQNRLVQYLLDTLHMHNTYSFG- 180
                      + E +R          ++S    + N + + VQ       ++  YS G 
Sbjct: 138 EVVEKAKDSANVEEEVREKNILILKRHLSSALRFQANMERKKVQVHKTVTFLNFQYSSGF 197

Query: 181 ----YFFCEVLNFANVVGNIFFLDTFLG-GAFLTYGTDVVRFSNMNQEQRTDPMIEVFPR 235
               Y F +VL F NV   ++ ++ FLG      YG  VV+  ++ Q +  +     FPR
Sbjct: 198 ISWIYLFTKVLYFLNVFAQLYLMNYFLGTNRHHWYGFGVVQ--DIVQGEPWE-RSGYFPR 254

Query: 236 ITKCTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCL 295
              C F +      IQ++   CVL +NI NEK             + S ++LV    V +
Sbjct: 255 AAVCDF-EVRQVANIQRYSVQCVLVINIFNEKIFVLLWFWYVILLLSSTVSLVQWFIVLV 313

Query: 296 LPSTRETILKRRFRFGT 312
            P   +  +K+     T
Sbjct: 314 FPCFSKWFVKQHLALST 330


>UniRef50_Q5C7A4 Cluster: SJCHGC08200 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC08200 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 171

 Score = 74.1 bits (174), Expect = 6e-12
 Identities = 38/118 (32%), Positives = 62/118 (52%), Gaps = 6/118 (5%)

Query: 18  YLIDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACIS----DGANPGHVINT 73
           + +D   +D+   R  Y ++  +L +C  +VT  + I EP++C       G+N G  IN 
Sbjct: 14  HFVDSVGLDDFADRCSYMLSFVLLVMCFTIVTLKSYIFEPLSCYIPTTFSGSNLGSYINA 73

Query: 74  FCWITYTFTMPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK 131
           FCWI  T  +   T +   +P      ++K+I+ YYQWV  +L  Q +L Y+P  IW+
Sbjct: 74  FCWINGTTPISVDTDQLD-NPAYWHSLEDKKIN-YYQWVSLVLALQAILCYLPRLIWE 129


>UniRef50_Q2L6M2 Cluster: Innexin1; n=2; Dugesiidae|Rep: Innexin1 -
           Dugesia japonica (Planarian)
          Length = 236

 Score = 69.7 bits (163), Expect = 1e-10
 Identities = 40/116 (34%), Positives = 62/116 (53%), Gaps = 8/116 (6%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACI--SDGANPGH-VINTFCWITYTFT 82
           D+   R+ +  T+  L +  IL+++N  +G PI C    + ++P     N +CWI  T+ 
Sbjct: 25  DDYCDRLSHHHTAMFLLITSILISSNQYVGNPIHCWVPKEFSDPWQKYANNYCWIKNTYV 84

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK--NWEEG 136
           +P    +  + P L  +  E  I+ YYQWVP +L  Q LLFY+P  IW+  NW  G
Sbjct: 85  LPPNL-EPGSIPKL-QERGELEIN-YYQWVPIVLLCQSLLFYLPSIIWRMLNWTLG 137


>UniRef50_O01634 Cluster: Innexin-12; n=2; Caenorhabditis|Rep:
           Innexin-12 - Caenorhabditis elegans
          Length = 408

 Score = 68.9 bits (161), Expect = 2e-10
 Identities = 69/270 (25%), Positives = 108/270 (40%), Gaps = 33/270 (12%)

Query: 27  NMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPG---HVINTFCWITYTFTM 83
           + V +++Y  T+  L L    +T  + +G PI C       G        +C++  TF +
Sbjct: 18  DFVDKLNYCATTIGLVLASAFITGWSFVGSPIDCWFPAYYKGWWAEYALDYCYVQNTFFV 77

Query: 84  PNTTSKTAAHPG----LGDDNDEKRIHS-----YYQWVPFMLFFQGLLFYIPHWIWKNW- 133
           P +  K          + D  +   +       YYQWVPF+L  Q +LFY P  IW+ + 
Sbjct: 78  PFSEDKAERSYNWEQLVADKQNTTSLKQTNQIGYYQWVPFILALQAMLFYFPVVIWRLFY 137

Query: 134 ---EEGKVRLIS---------EGMRGTMASIAD--DKNNRQNRLVQYLLDTLHMHNTYSF 179
               +    L +         E  +GT+ +IA    +   +N +V+ L    +  N  + 
Sbjct: 138 GMAGQNVTSLCNTCTATEGNEESRKGTITTIAGYISQKRHRNLIVKQLSGFQNRANGSAV 197

Query: 180 --GYFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRIT 237
              Y F + L   NV+     L   LG     +G +V        E    P    FPR+T
Sbjct: 198 ITSYLFMKALFLINVLFQFVLLKRMLGVDSYFWGAEVTSDLWSGNEW---PETGNFPRVT 254

Query: 238 KCTFHKFGASGTIQKHDALCVLALNILNEK 267
            C +        I KH   CVL +N+ NEK
Sbjct: 255 MCEYEVRNLD-NIHKHSVQCVLMINMFNEK 283


>UniRef50_Q38HR8 Cluster: Innexin 3; n=1; Hirudo medicinalis|Rep:
           Innexin 3 - Hirudo medicinalis (Medicinal leech)
          Length = 479

 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 83/369 (22%), Positives = 139/369 (37%), Gaps = 54/369 (14%)

Query: 6   LVSSVAGFVKVRYLIDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGA 65
           LV  V    K    +D  + D    R+++  TSAIL +  +LV+    +G+PI C     
Sbjct: 4   LVKVVLNLAKGEERLDDTITD----RLNHVTTSAILVVMAVLVSTKQYVGDPIECWCPKE 59

Query: 66  ---NPGHVINTFCWITYTFTMPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLL 122
              N     ++FCWI  T+ +P       +  G G         +YYQWVP +L  Q  L
Sbjct: 60  FTKNQVEYADSFCWIRGTYYVPFEREDMPSVYGRG----RTPTVTYYQWVPLILLVQSFL 115

Query: 123 FYIPHWIWKNWEE----GKVRLISEGMRGTMASIADD-----KNNRQNRLVQYL------ 167
           F +P   W+  +          I  G + +   + +D      ++   +L +YL      
Sbjct: 116 FSLPSLFWRGMQAKSGFDASNFIDYGRKVSSPKVKNDIRGTLLDHMTLQLERYLKYGNPQ 175

Query: 168 ---------LDTLHMHNTYSFGYFFCEVLNF---ANVVGNIFFLDTFLGGAFL------- 208
                    +   H+     F +F    LN+     +    F+L   +G  FL       
Sbjct: 176 SKTKAGSFTISMKHLFTRTCFRFFGHRRLNYFCTLQLATKFFYLVNSVGQIFLLDYLLNM 235

Query: 209 ---TYGTDVVRFSNMNQEQRTDPMIEV---FPRITKCTFHKFGASGTIQKHDALCVLALN 262
              TYG+D++    +      + +      FP++T C F K    G +  +   C L +N
Sbjct: 236 KFHTYGSDILSSLTLGSGSNRELVRHQETRFPKVTMCDF-KVRRLGAVHNYSIQCALTVN 294

Query: 263 ILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPSTRETILKRRFRFGTPNGVEALVRK 322
           + NEK            S  +  +L   +   L+   R   +K          +E + +K
Sbjct: 295 LFNEKVFLILWLWMVFISAANFFSLFRWSLRNLMGGERYGYIKNLLLIS--GLIEPIKKK 352

Query: 323 TQVGDFLLL 331
            +  DF LL
Sbjct: 353 AKTRDFFLL 361


>UniRef50_Q29ZM7 Cluster: Pannexin 4; n=3; Opisthobranchia|Rep:
           Pannexin 4 - Aplysia californica (California sea hare)
          Length = 413

 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 40/109 (36%), Positives = 59/109 (54%), Gaps = 8/109 (7%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPG-HV--INTFCWITYTFT 82
           D++  R+++  T+ IL +  ++V+A   +G+PI C       G HV   N  CWI+ T+ 
Sbjct: 26  DDLNDRVNHLYTTGILIIFTVVVSARQYVGDPIRCWCPAQFTGAHVDYTNNICWISNTYY 85

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK 131
           +P         P   D   E ++ +YYQWVP ML  Q LLFYIP  IW+
Sbjct: 86  IP----MDFIVPESIDKRMETQL-TYYQWVPVMLLIQALLFYIPCIIWR 129



 Score = 41.1 bits (92), Expect = 0.048
 Identities = 26/87 (29%), Positives = 39/87 (44%), Gaps = 4/87 (4%)

Query: 181 YFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCT 240
           Y   +VL  +N +G  F ++ FL   +  YG  V+    +  E  T      FPR+T C 
Sbjct: 210 YLAMKVLYISNAIGQFFMMNAFLATDYNLYGFQVLE-DLIEGESWTAS--RRFPRVTMCD 266

Query: 241 FHKFGASGTIQKHDALCVLALNILNEK 267
           F +         +   CVL +N+ NEK
Sbjct: 267 F-EIRQMTNKHNYSVQCVLPINLFNEK 292


>UniRef50_Q2L6M8 Cluster: Innexin7; n=2; Eukaryota|Rep: Innexin7 -
           Dugesia japonica (Planarian)
          Length = 407

 Score = 67.7 bits (158), Expect = 5e-10
 Identities = 72/293 (24%), Positives = 126/293 (43%), Gaps = 42/293 (14%)

Query: 5   GLVSSVAGFVKVRYLIDKAVIDNMVFRMHYRITSAILFLCCILV-TANNLIGEPIAC--- 60
           GL+S++   +K+   + +   D+ V R++   T  IL +  I++ T + ++GEP+ C   
Sbjct: 4   GLLSTLQK-IKLTSHLKRISDDDFVDRINNFYTPLILTILTIVICTKSYIVGEPLQCWVP 62

Query: 61  ISDGANPGHVINTFCWITYTFTMPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQG 120
           +           ++C+I  T+ +P    K    P   D  +   +  YYQWVPF+L  Q 
Sbjct: 63  VHFSGGWEKFSESWCYIKNTYYVP----KYKELPTEKDMREHSELQ-YYQWVPFVLGLQA 117

Query: 121 LLFYIPHWIWK--NWEEGKVRLISEGMRGTMAS--IADDKNNRQNRLVQYLLDTLHM--- 173
           +LF  P   WK  NW +G++ +     RG  +S  + D ++     + +++ ++L     
Sbjct: 118 VLFLFPSIFWKFSNW-QGRLHIKPLMQRGVKSSFEVGDSRSTTLKEIAEHIRNSLFKSQY 176

Query: 174 --HNTYSFG-----------------YFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDV 214
             H T S G                 Y   ++L   N++     +  FL   F      +
Sbjct: 177 GNHPTLSAGNDKCCGFINSGFYLTFCYLISKLLYLTNIIIQFIIVHRFLKADFFFGFNLL 236

Query: 215 VRFSNMNQEQRTDPMIEVFPRITKCTFHKFGASGTIQKHDALCVLALNILNEK 267
            + S+ +  Q T     +FPR+T C F      G        CVL +N+ NEK
Sbjct: 237 TKLSSGSDWQETG----LFPRVTMCDF-TTPRIGQDLPTTMQCVLVINLFNEK 284


>UniRef50_Q2L6N2 Cluster: Innexin2; n=1; Dugesia japonica|Rep:
           Innexin2 - Dugesia japonica (Planarian)
          Length = 466

 Score = 67.3 bits (157), Expect = 6e-10
 Identities = 36/110 (32%), Positives = 57/110 (51%), Gaps = 9/110 (8%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIAC-ISDGANPG--HVINTFCWITYTFT 82
           D+M  R++Y+++S ++F    L+     +G+PI C I      G       +CW+  T+ 
Sbjct: 58  DDMADRLNYKVSSLLMFGFISLIGLRQYVGKPIQCWIPQEFTRGWEEYSENYCWVASTYF 117

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKN 132
            P +       P   D   +KR+  YYQW P +L  QG LFY+P+ IWK+
Sbjct: 118 APISEKL----PSKVDR--QKRLIGYYQWAPIILAIQGFLFYMPYLIWKS 161


>UniRef50_Q9U3N4 Cluster: Innexin-6; n=2; Caenorhabditis|Rep:
           Innexin-6 - Caenorhabditis elegans
          Length = 389

 Score = 65.7 bits (153), Expect = 2e-09
 Identities = 67/284 (23%), Positives = 117/284 (41%), Gaps = 31/284 (10%)

Query: 6   LVSSVAGFVKVRYLIDKAVID---NMVFRMHYRITSAILFLCCILVTANNLIGEPIACIS 62
           + S V     V  LI +  +    ++  R++ R+T  IL +   L+ +++ IG+PI C +
Sbjct: 1   MASQVGAINSVNALISRVFVQPKGDLADRLNSRVTVVILAVSSALLLSSHFIGDPITCWT 60

Query: 63  DG---ANPGHVINTFCWITYTFTMPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQ 119
                A   + +N +C++  T+ +P             ++   K    YYQWVP++   Q
Sbjct: 61  PAQFNAQWVNFVNQYCFVHGTYFVPLDQQLA-----FEEEERTKVSIQYYQWVPYVFALQ 115

Query: 120 GLLFYIPHWIWKNWEEGKVRLISEGMR--GTMASIADDKNNR--------QNRLVQYLLD 169
             LFYIP +IWK         ++  ++      S   DK+++        + R   Y+ D
Sbjct: 116 AFLFYIPRFIWKAMIAYSGYDLAAAVKYVDRFWSENRDKDDKFKTRLAAFEGRPSVYIWD 175

Query: 170 TLHM-----HNTYSFGYFFCEVLNFANVVGNIFFLDTFLGGAFLT-YGTDVVRFSNMNQE 223
            + +         +  Y    V    N     + L   L  +  T +G  ++       +
Sbjct: 176 GIRLARKKRSRNMALFYTLSTVWQAVNAWIQFYILTQLLDSSIYTLWGPSILGDLLQGND 235

Query: 224 QRTDPMIEVFPRITKCTFHKFGASGTIQKHDALCVLALNILNEK 267
            +T      FPRI  C F++     ++Q    LCVL LNI  EK
Sbjct: 236 WQTTGH---FPRIVHCDFNR-RRPASVQLDTVLCVLTLNIYYEK 275


>UniRef50_Q2L6M9 Cluster: Innexin5; n=3; Platyhelminthes|Rep:
           Innexin5 - Dugesia japonica (Planarian)
          Length = 399

 Score = 64.9 bits (151), Expect = 3e-09
 Identities = 71/297 (23%), Positives = 122/297 (41%), Gaps = 39/297 (13%)

Query: 27  NMVFRMHYRITSAILFLCCILVTANNLIGEPIAC-ISDGANPG--HVINTFCWITYT-FT 82
           + V +++Y+ TS +L +  I++     +G+PI C +               CW+  T F 
Sbjct: 23  DFVDQLNYQFTSGLLIVFIIIIGIRQYVGKPIQCWVPQEFTRSWEEYAENVCWVQNTYFL 82

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKNWEEGKVRLIS 142
           +P+        P    +  + R  SYYQWV  +L  Q ++ ++PH IW+ W   +V ++ 
Sbjct: 83  LPHEDV-----PNNEYELSKVRYISYYQWVAIVLAGQAVMSWVPHLIWRVWSR-RVPILL 136

Query: 143 EGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYS-----FG---------------YF 182
              R       + +    + LV  L +       +      FG               + 
Sbjct: 137 RSAREASFPDREIRRKAISCLVAALEEQTESGARFRKIKGIFGKCLGGVNPTARVTLLFI 196

Query: 183 FCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVR-FSNMNQEQRTDPMIEVFPRITKCTF 241
           F  +L  AN +G IF +  F+G    T+G  V R   + N+ Q    +   FPR+T CT 
Sbjct: 197 FVRLLFIANNIGQIFMMKKFIGTNETTFGITVFRDLLDGNEGQ----ISATFPRVTYCTI 252

Query: 242 HKFGASGTIQ--KHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALV-YSAAVCL 295
            K    G ++   +   CVL +N   EK            S+++ L  V ++  VC+
Sbjct: 253 -KVRKMGQVKPGSYTLQCVLPINYFVEKVYVFLWFWFIILSILTTLNTVQWTLNVCV 308


>UniRef50_Q9U3K5 Cluster: Innexin-2; n=2; Caenorhabditis|Rep:
           Innexin-2 - Caenorhabditis elegans
          Length = 419

 Score = 64.9 bits (151), Expect = 3e-09
 Identities = 61/251 (24%), Positives = 106/251 (42%), Gaps = 25/251 (9%)

Query: 31  RMHYRITSAILFLCCILVTANNLIGEPIACIS----DGANPGHVINTFCWITYTFTMPNT 86
           R++   T  +L    + ++     G+PI C +     G+  G+V + FC+I  T+ +PN 
Sbjct: 30  RVNAWFTPFVLVAMTLAISCKQYFGQPIKCWTPREFSGSWDGYV-HDFCFIENTYFVPNG 88

Query: 87  TSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKNWEEGKVRLISEGMR 146
           T  T       D+    R  +YY+WVP +L FQ  +F +P+ +W  + +     +   +R
Sbjct: 89  TEVT-------DEARGGRHINYYRWVPLVLLFQAAMFVLPYHLWNLFHKRTTINLKGSLR 141

Query: 147 ---GTMASI--ADDKNNRQNRLVQYLLDTLHMHN-TYSF----GYFFCEVLNFANVVGNI 196
              G +  +  A    +    +   L D  +  N  Y F     YF  ++    N +  +
Sbjct: 142 FFEGALKKLEPAQACESFAGEIWNRLSDIRNSSNKLYGFQATINYFLLKLGFIVNCILQM 201

Query: 197 FFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFGASGTIQKHDAL 256
             L  FL      +G       N+  +   +    +FPRI  C F K    G   +H   
Sbjct: 202 VLLKHFLDVDDYFWG--FFHLWNVEFKGTAEKEDSIFPRIVLCDF-KVRNLGQQHQHTVS 258

Query: 257 CVLALNILNEK 267
           C++ LN++ EK
Sbjct: 259 CIMILNMIIEK 269


>UniRef50_Q2L6N1 Cluster: Innexin3; n=2; Dugesia japonica|Rep:
           Innexin3 - Dugesia japonica (Planarian)
          Length = 483

 Score = 63.3 bits (147), Expect = 1e-08
 Identities = 36/110 (32%), Positives = 57/110 (51%), Gaps = 9/110 (8%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIAC-ISDGANPG--HVINTFCWITYTFT 82
           D+ V R++Y+ T  +LF+   L+     +G+PI C I      G       +CW++ T+ 
Sbjct: 62  DDFVDRLNYQFTGLLLFMFIGLIGIRQYVGKPIQCWIPQEFTRGWEEYTENYCWVSNTY- 120

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKN 132
             +  ++  +     D  +E+ I  YYQW P +L  Q LLFYIP  IW+N
Sbjct: 121 FASIQNRMPSK----DTRNEQMI-GYYQWAPILLGLQSLLFYIPCLIWRN 165



 Score = 33.5 bits (73), Expect = 9.5
 Identities = 22/87 (25%), Positives = 37/87 (42%), Gaps = 4/87 (4%)

Query: 181 YFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCT 240
           Y   + L   N++G ++ ++ F+G  +  YG  V+       E         FPR+T C 
Sbjct: 255 YISIKFLYLINIIGQLYLMEKFIGTKYTFYGIRVLWDLMRGHEWHHSGN---FPRVTFCD 311

Query: 241 FHKFGASGTIQKHDALCVLALNILNEK 267
             +    G    +   CVL +N+  EK
Sbjct: 312 L-EAKKLGKNHLYSLQCVLPMNMFLEK 337


>UniRef50_Q8I6U2 Cluster: Innexin 1; n=1; Hirudo medicinalis|Rep:
           Innexin 1 - Hirudo medicinalis (Medicinal leech)
          Length = 414

 Score = 62.5 bits (145), Expect = 2e-08
 Identities = 37/129 (28%), Positives = 62/129 (48%), Gaps = 10/129 (7%)

Query: 6   LVSSVAGFVKVRYLIDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGA 65
           L  SV+   ++++ +D    D+ V R+  + T  IL     LV+    +G+PI C     
Sbjct: 4   LFKSVSSIREIKFRMD----DDYVDRLSRQYTVVILICFGFLVSTKQFVGKPITCWCPAQ 59

Query: 66  -NPGH--VINTFCWITYTFTMPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLL 122
               H    +  CW + T+ +P      A H  +   +   R+ SYYQW+P +L FQ LL
Sbjct: 60  FTSSHRDYTDAVCWFSNTYFLPLEDELKADHLSI---HTNIRMISYYQWIPLILIFQALL 116

Query: 123 FYIPHWIWK 131
            ++P  +W+
Sbjct: 117 AFVPCLLWR 125


>UniRef50_Q9N3R5 Cluster: Innexin protein 22; n=2;
           Caenorhabditis|Rep: Innexin protein 22 - Caenorhabditis
           elegans
          Length = 462

 Score = 60.9 bits (141), Expect = 5e-08
 Identities = 67/296 (22%), Positives = 117/296 (39%), Gaps = 29/296 (9%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHVIN---TFCWITYTFT 82
           DN   R+ +  T  IL     LV++N + G+PI C+     P    N    FC+      
Sbjct: 20  DNGAERIVHTTTIQILICFGFLVSSNMMFGQPITCLMLPETPDSSANYFHDFCFYQDKLR 79

Query: 83  MP--NTTSKTAAHPGLGDDND---EKRIHSYYQWVPFMLFFQGLLFYIPHWIWKNWEEGK 137
           +P  +   K +   G  + N+   ++   +YYQW PF++F Q  +  +P  +WK +  G 
Sbjct: 80  IPPLHNAVKRSTRQGTMNINNIMPQEVAVTYYQWTPFIIFLQVAMCLVPALMWKFF--GL 137

Query: 138 VRLISEGMRGTMASIA----DDKNNRQN--------RLVQYL----LDTLHMHNTYSFGY 181
                      + S+A    DDK +  N          +++L     +   MH T    Y
Sbjct: 138 HYFYGHDFAAIVRSLASKKKDDKMDSSNSNYEVDARETLRWLEHKKRERFGMHTTMMI-Y 196

Query: 182 FFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTF 241
              + + FA+++     +        L +G   + +  +N   + +    VFP+I  C  
Sbjct: 197 VAMKWMTFASLLFQFNLMAKIYASGELLWGVH-ISYELLNGAYK-NVYTGVFPQIVGCNP 254

Query: 242 HKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLP 297
           H+    G + +    C+L  N +N K             +VS  + V   A+  LP
Sbjct: 255 HRAQLGGVVNEFIMRCILPQNFVNSKVFLFLYWWYILAMLVSIYSAVQFTAMLFLP 310


>UniRef50_Q5DA25 Cluster: SJCHGC09647 protein; n=4; Schistosoma
           japonicum|Rep: SJCHGC09647 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 458

 Score = 60.5 bits (140), Expect = 7e-08
 Identities = 48/178 (26%), Positives = 76/178 (42%), Gaps = 15/178 (8%)

Query: 13  FVKVRYLIDKAVIDNMVFRMHYRITSAILFL-CCILVTANNLIGEPIACI----SDGANP 67
           F K  Y    AV D   F     + + +LFL  CI+V+A       I+C       G N 
Sbjct: 10  FGKFNYANRVAVED---FSDRLSLFTVVLFLIACIVVSAKQYFLNSISCYIPVKPTGENY 66

Query: 68  GHVINTFCWITYTFTM-PNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIP 126
              +  +CW+  T  + P+    T   P   +  D+ R  +YYQWVPF+L  Q + FYIP
Sbjct: 67  NSYLTDYCWVHGTIPLRPDEPMPTT--PKEWEQYDQLRRITYYQWVPFVLGLQCIFFYIP 124

Query: 127 HWIWK----NWEEGKVRLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYSFG 180
           H  W+    +   G +  + +       S    + ++  R+ ++L D +  H     G
Sbjct: 125 HIAWQAVCAHRSGGDLFALVKAAADAAISERGSRKSQVKRVAEFLEDMIDGHKDCRHG 182


>UniRef50_Q38HR5 Cluster: Innexin 6; n=1; Hirudo medicinalis|Rep:
           Innexin 6 - Hirudo medicinalis (Medicinal leech)
          Length = 480

 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 35/109 (32%), Positives = 49/109 (44%), Gaps = 10/109 (9%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGA-NPGHV--INTFCWITYTFT 82
           D+ V R+H   T   L L   +V      G PI C   G  +P HV   N+ CW+  T+ 
Sbjct: 23  DDSVDRLHRHYTCCFLLLSASMVGLKQFAGAPIDCWCPGQFSPSHVSYANSICWVNGTYY 82

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK 131
           +P           L   N  +    YYQWVPF+L  Q  +F +P + W+
Sbjct: 83  VPFDDY-------LPLPNQSRTAILYYQWVPFLLLTQSFVFTLPGFFWR 124



 Score = 38.7 bits (86), Expect = 0.25
 Identities = 33/133 (24%), Positives = 55/133 (41%), Gaps = 8/133 (6%)

Query: 185 EVLNFANVVGNIFFLDTFLG-----GAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKC 239
           ++LN  N      FL++FL      G   T  T + R S + +          FP++T C
Sbjct: 245 KLLNLVNTCFQFLFLNSFLNKTPHDGFLRTIATSLERIS-LGELVNFQLDQGRFPKVTMC 303

Query: 240 TFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPST 299
            FH       + ++   CVL +N+ NEK             +++ L L +S    + P  
Sbjct: 304 DFH-IRQQVNLHRYTVQCVLPINLFNEKVFLMLWVWLVLLILITVLNL-FSWTPVMFPCC 361

Query: 300 RETILKRRFRFGT 312
           +   +K+R R  T
Sbjct: 362 QAGYIKQRLRLVT 374


>UniRef50_Q2L6M5 Cluster: Innexin10; n=1; Dugesia japonica|Rep:
           Innexin10 - Dugesia japonica (Planarian)
          Length = 415

 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 33/119 (27%), Positives = 60/119 (50%), Gaps = 6/119 (5%)

Query: 18  YLIDKAV-IDNMVFRMHYRITSAILFLCCILVTANNLIGEPIAC----ISDGANPGHVIN 72
           + ++K V I++   +  +  + AIL +C I+++    +   I+C    +  G++    I 
Sbjct: 11  FKVEKYVGIEDGADKASFLFSVAILAVCSIIISTKQYVTTDISCYIPIVVSGSDFEKFIR 70

Query: 73  TFCWITYTFTMPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK 131
            +CW+  T    +  S              ++I+ YYQWVPF+L  QG+LFY+P  IW+
Sbjct: 71  NYCWVHGTIPFRSNESLPQTKEEWMTAEYTRKIN-YYQWVPFVLGLQGVLFYLPRLIWR 128



 Score = 34.7 bits (76), Expect = 4.1
 Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 7/91 (7%)

Query: 181 YFFCEVLNFANVVGNIFFLDTFL--GGAFLT--YGTDVVRFSNMNQEQRTDPMIEVFPRI 236
           YF  ++L   N +G I  +  FL  G   L   +G  ++    ++ +Q T+ ++  FPR 
Sbjct: 207 YFVIKILYLINAIGQILLMQNFLRLGTTKLNVAFGWTILH-DIISGKQWTENLL--FPRT 263

Query: 237 TKCTFHKFGASGTIQKHDALCVLALNILNEK 267
           T C               A C L +N+LNEK
Sbjct: 264 TFCFIGDISLVAVKNHFVAQCTLPINMLNEK 294


>UniRef50_Q22549 Cluster: Innexin-10; n=3; Caenorhabditis|Rep:
           Innexin-10 - Caenorhabditis elegans
          Length = 559

 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 33/108 (30%), Positives = 53/108 (49%), Gaps = 7/108 (6%)

Query: 27  NMVFRMHYRITSAILFLCCILVTANNLIGEPIACISD---GANPGHVINTFCWITYTFTM 83
           + V R+H   T  +L    +LV+     G+P+ C+      ++       +CW + T+ +
Sbjct: 20  DFVDRLHSYFTCNLLIGLAVLVSFKQFGGKPVECLVPDIFSSSWEQYAENYCWASDTYYV 79

Query: 84  PNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK 131
           P  T++  A  GL  D   +R  SYYQWVPF L  +   F +P  +WK
Sbjct: 80  P--TNEPVA--GLQSDEKRQRKISYYQWVPFFLLLEAACFRLPSLLWK 123



 Score = 37.1 bits (82), Expect = 0.77
 Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 7/89 (7%)

Query: 181 YFFCEVLNFANVVGNIFFLDTFLG-GAFLTYGTD-VVRFSNMNQEQRTDPMIEVFPRITK 238
           Y   +    ANV   + F++ FL    +  YG   +V   N    +++     +FPR++ 
Sbjct: 199 YLCTKFFYLANVCLQLMFMNRFLETDKYKWYGMGALVDLLNGTTWEQSG----MFPRVSL 254

Query: 239 CTFHKFGASGTIQKHDALCVLALNILNEK 267
           C F      G +Q+H   CVL +NI NEK
Sbjct: 255 CDFD-VRVMGNMQEHTIQCVLVINIFNEK 282


>UniRef50_P91827 Cluster: Putative uncharacterized protein inx-20;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein inx-20 - Caenorhabditis elegans
          Length = 483

 Score = 58.8 bits (136), Expect = 2e-07
 Identities = 72/312 (23%), Positives = 121/312 (38%), Gaps = 40/312 (12%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGH---VINTFCWITYTFT 82
           D++  R+HY  T+  L L  +L++     G PI C                +CW   T+ 
Sbjct: 45  DDIFDRLHYYYTTTFLLLTAVLISLKMFGGRPIECWLPAEYKSSWEDYTEMYCWARNTYV 104

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK-NWEEGKVRL- 140
              T  +    P +   N E  + SYYQWVPF L +    FY P  IW+  +++  +RL 
Sbjct: 105 ---TAFEDDNLPEVV--NREYTMVSYYQWVPFFLVYVAFSFYAPCLIWRLFYDKSGIRLK 159

Query: 141 ----------------ISEGMRGTMASIADDKNNR--------QNRLVQYLLDTLHMHNT 176
                            +  +RG  A ++    +R         +  V  + +  +  + 
Sbjct: 160 DIMGFANDKANVVPTQRTANIRGLSAHLSSVFKHRFRIGEKHPYHHKVFRIFNVRYYESY 219

Query: 177 YSFGYFFCEVLNFANVVGNIFFLDTFLG-GAFLTYGTDVVRFSNMNQEQRTDPMIEVFPR 235
            ++ Y   + L   NV+  ++F+  FL   +   YG  +     M +  +       FP 
Sbjct: 220 LTYLYLAIKCLFLMNVLTQMYFMSRFLELDSHRYYGYGIFYDLIMGKGWKES---SNFPV 276

Query: 236 ITKCTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVS-GLALVYSAAVC 294
           +T C   +    G +Q+H   CVL +NI  EK            S++S G  L +  A  
Sbjct: 277 VTYCDM-QIRILGHVQRHTVQCVLVINIFTEKIFFILWLWYTMLSLISFGSILSWIFASI 335

Query: 295 LLPSTRETILKR 306
                R+ I +R
Sbjct: 336 PFNQRRQFIARR 347


>UniRef50_Q8MWD8 Cluster: Innexin 1; n=2; Penaeus monodon|Rep:
           Innexin 1 - Penaeus monodon (Penoeid shrimp)
          Length = 149

 Score = 58.4 bits (135), Expect = 3e-07
 Identities = 30/95 (31%), Positives = 47/95 (49%)

Query: 234 PRITKCTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAV 293
           P   KCTFH+FGASGTI++ + LC+L  NI+NEK              ++ + L++   V
Sbjct: 50  PAQAKCTFHQFGASGTIKRLEYLCILRQNIINEKVFLVMWFWFVVLVSLTSMQLIWQLLV 109

Query: 294 CLLPSTRETILKRRFRFGTPNGVEALVRKTQVGDF 328
              P  R  +++   +       E ++R    GDF
Sbjct: 110 LYSPLVRLRLVESHTKGKLSPKAEQVIRGMHAGDF 144


>UniRef50_Q03412 Cluster: Innexin unc-7; n=4; Caenorhabditis|Rep:
           Innexin unc-7 - Caenorhabditis elegans
          Length = 522

 Score = 57.2 bits (132), Expect = 7e-07
 Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 11/117 (9%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHV---INTFCWITYTFT 82
           D+ V +++Y  T+ IL    +LV+A   +G PI C         +      +CW+  T+ 
Sbjct: 139 DDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENYCWVQNTYW 198

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKN---WEEG 136
           +P         P        ++I  YYQWVPF+L  + LLFY+P  +W+    W  G
Sbjct: 199 VPMQEDI----PREIYSRRNRQI-GYYQWVPFILAIEALLFYVPCILWRGLLYWHSG 250



 Score = 51.2 bits (117), Expect = 4e-05
 Identities = 36/129 (27%), Positives = 56/129 (43%), Gaps = 4/129 (3%)

Query: 181 YFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCT 240
           Y   +VL  ANV+   F L+  LG   L YG  +++      E     M   FPR+T C 
Sbjct: 322 YIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLMHAIEWEQTGM---FPRVTLCD 378

Query: 241 FHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPSTR 300
           F +    G I +H   CVL +N+ NEK             +V+    +Y   +  +PS  
Sbjct: 379 F-EVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQG 437

Query: 301 ETILKRRFR 309
            + +++  R
Sbjct: 438 MSFVRKYLR 446


>UniRef50_Q38HQ9 Cluster: Innexin 12; n=1; Hirudo medicinalis|Rep:
           Innexin 12 - Hirudo medicinalis (Medicinal leech)
          Length = 381

 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 59/247 (23%), Positives = 99/247 (40%), Gaps = 32/247 (12%)

Query: 40  ILFLCCILVTANNLIGEPIACISDGANPGHVINTFCWITYTFTMPNTTSKTAAHPGLGDD 99
           IL +  ++ T  N   +PI+C       G  I     + YT        +T  +    + 
Sbjct: 33  ILGIFALVATTGNYFHQPISCYCPTEFKGSEIEFVEKVCYT--------QTTYYLNYAEF 84

Query: 100 NDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK--NWEEG-KVRLISEGMRGTMASIADDK 156
           +   +  SYYQW+  +L  Q  LFY+P  IWK    + G  +  I++ ++    ++  + 
Sbjct: 85  DTNTQSVSYYQWISLILAGQAFLFYLPSSIWKIMGKKSGLALSSITDSVKRCRRNLDFEG 144

Query: 157 NNRQNRLVQYLLDT-LHMHNT----------------YSFGYFFCEVLNFANVVGNIFFL 199
           N    +     L+  LH+ N                  ++ Y F + L   N VG +F L
Sbjct: 145 NETALQFASNTLNNYLHVQNKNTSEKKKKWLIFKGNYLAYLYLFIKFLYCLNAVGQLFIL 204

Query: 200 DTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFGASGTIQKHDALCVL 259
           + FLG  +  YG   + F +  +   T      FP++T C    F     I      CVL
Sbjct: 205 NAFLGDNYHFYG---IEFLDNMRNGVTWKSSRKFPKVTFCNVSIF-VPFNIHHRFLQCVL 260

Query: 260 ALNILNE 266
            +N++ E
Sbjct: 261 PMNLIYE 267


>UniRef50_O61966 Cluster: Innexin protein 4; n=2;
           Caenorhabditis|Rep: Innexin protein 4 - Caenorhabditis
           elegans
          Length = 554

 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 8/109 (7%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDG---ANPGHVINTFCWITYTFT 82
           D+ V R+ Y  TS+ L +  +LV+     G P+ C       A+       +CW   T+ 
Sbjct: 56  DDFVDRLSYFYTSSFLIMMAVLVSFKQFGGRPLECWVPAQFTASWEAYTEMYCWAQNTYW 115

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK 131
           +P           +     E R  SYYQWVPF L  Q  L+YIP  +W+
Sbjct: 116 VPIDQDIP-----VDISEREYRQISYYQWVPFFLLLQAFLYYIPCLMWR 159



 Score = 47.2 bits (107), Expect = 7e-04
 Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 9/168 (5%)

Query: 171 LHMHNTYSFG-YFFCEVLNFANVVGNIFFLDTFLG-GAFLTYGTDVVRFSNMNQEQRTDP 228
           +  + +Y  G Y   +++   N++ N+  ++ FL    +  YG  V+R        RT  
Sbjct: 225 MRYYESYVTGMYLATKIMYVGNILTNLVLVNKFLETDEYSIYGLGVLRDLLFG---RTWI 281

Query: 229 MIEVFPRITKCTFHKFGASGTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALV 288
               FPR+T C F +    G  Q+H   CVL +NI NEK             V S L ++
Sbjct: 282 ESGNFPRVTLCDF-EVRVLGNNQRHSVQCVLVINIFNEKIFILIWLWFTLLFVASTLDML 340

Query: 289 YSAAVCLLPSTRETILKRRFRFGTPNGVEALVRK---TQVGDFLLLHL 333
           Y  ++ +    R   + R     +      L RK    QV  FL  +L
Sbjct: 341 YWFSISMFHRDRFRFVLRHLELTSDPDKPELFRKEKRKQVEHFLRTYL 388


>UniRef50_Q23593 Cluster: Innexin-8; n=3; Caenorhabditis|Rep:
           Innexin-8 - Caenorhabditis elegans
          Length = 382

 Score = 54.8 bits (126), Expect = 4e-06
 Identities = 55/258 (21%), Positives = 104/258 (40%), Gaps = 22/258 (8%)

Query: 25  IDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACI---SDGANPGHVINTFCWITYTF 81
           ID+    +   IT+ +     IL +A   +G  + C    +   + G     +C++  T+
Sbjct: 19  IDDASDTLSCLITAFLFITAAILTSAKTYVGSAMECWLPQTYSGDWGEFAENYCFLKDTY 78

Query: 82  TMPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK---NWEEGKV 138
             P   S T     +   + E+   +YYQW    L   G+ F IP ++W+   +  +  V
Sbjct: 79  FYPRQQSMT----DIPMYHKERHRLTYYQWSSMYLAVAGIAFMIPKFLWRLSQSTTDMPV 134

Query: 139 RLISEGMRGTMASIADDKNNRQNRLVQYL---LDTLHMHNTYSF-----GYFFCEVLNFA 190
               +          D ++ +   + +++   + ++H  + +SF      Y   ++L   
Sbjct: 135 VYFCDTANEIKNETEDKRSAKIKEMARFMRTKITSVHTPSLFSFIRMYMVYSVIKILYLV 194

Query: 191 NVVGNIFFLDTFLG-GAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFGASGT 249
           N +     +  FLG    L +G  +  F N+     T     +FPR+T C F     +G 
Sbjct: 195 NAIAQFVIIAIFLGQKRNLFWGWTL--FMNL-LNGITWETTGLFPRVTFCDFQVREMAGN 251

Query: 250 IQKHDALCVLALNILNEK 267
            +     CV+ +N  NEK
Sbjct: 252 NRDETVECVIGINEFNEK 269


>UniRef50_Q2L6N0 Cluster: Innexin4; n=1; Dugesia japonica|Rep:
           Innexin4 - Dugesia japonica (Planarian)
          Length = 445

 Score = 53.6 bits (123), Expect = 8e-06
 Identities = 31/109 (28%), Positives = 54/109 (49%), Gaps = 9/109 (8%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACIS-DGANPG--HVINTFCWITYTFT 82
           D+ + R++Y+IT  +LFL   ++     +G+PI C S      G       +CW++ T+ 
Sbjct: 24  DDFIDRLNYQITGILLFLFIGIIGIRQYVGKPIQCWSPQEFTRGWEEYAENYCWVSNTY- 82

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK 131
             + +++    P     N +  +  YYQW    L  Q L+FYIP  +W+
Sbjct: 83  YASVSNRLPDKP-----NRKDLMIGYYQWAWIFLGVQALMFYIPCILWR 126



 Score = 34.3 bits (75), Expect = 5.5
 Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 4/93 (4%)

Query: 175 NTYSFGYFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFP 234
           N  +  Y   ++L   N +  ++ ++ F+G  +  YG  V++   +      D     FP
Sbjct: 213 NCLTILYLLIKLLYILNAISQVYLMEIFIGTKYTFYGVYVLK-DLLRGLHWADS--GHFP 269

Query: 235 RITKCTFHKFGASGTIQKHDALCVLALNILNEK 267
           R+T C F +    G    +   CVL +N++ EK
Sbjct: 270 RVTFCDF-QAKKLGKNHLYTLQCVLPINMILEK 301


>UniRef50_Q3KZ46 Cluster: SJCHGC07836 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC07836 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 116

 Score = 53.2 bits (122), Expect = 1e-05
 Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 7/97 (7%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIAC---ISDGANPGHVINTFCWITYTFT 82
           D+   R  +  TS +L +  ++++A   IG+PIAC               + CW+T T+ 
Sbjct: 23  DDFSDRFSHTFTSLLLIIFTLIISARQYIGKPIACWVPTEFTRAQEEYAESVCWVTSTYF 82

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQ 119
           +P   ++    P    + + ++IH YYQWVPF+L  Q
Sbjct: 83  IP---TQEVNVPENISERENRKIH-YYQWVPFILMIQ 115


>UniRef50_O62136 Cluster: Innexin-14; n=3; Caenorhabditis|Rep:
           Innexin-14 - Caenorhabditis elegans
          Length = 434

 Score = 52.8 bits (121), Expect = 1e-05
 Identities = 63/282 (22%), Positives = 107/282 (37%), Gaps = 53/282 (18%)

Query: 31  RMHYRITSAILFLCCILVTANNLIGEPIACI-----SDGANPGHVINTFCWI--TYTFTM 83
           R+H   T  +L    +L  A    G PI C+      D  +    I+ FC    T+ + +
Sbjct: 27  RLHL-FTVYLLGFFVLLTGAKQHFGNPIDCMLPKQHDDLKSWRDYIHNFCLFYGTFRYDV 85

Query: 84  PNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKNWEE----GKVR 139
            N TS+       G   ++  ++ YYQWVPF   FQ   F +P W W   ++        
Sbjct: 86  SNGTSE------FGSYTEDASVN-YYQWVPFFFAFQVCCFLLPFWCWAYMQKLIYIDMAF 138

Query: 140 LISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYSFGYFFCEVLNFA--------- 190
           ++    +       +    + +R+V Y+ D       +  GY      N A         
Sbjct: 139 IVDYSGKINSEKTFEKTKEKVDRIVNYMHDHFKFRRAHKMGYLSWITFNSAFPSVLYSLT 198

Query: 191 ------NVVGNIFFLDTFLGGAFLTYGTDVV-----------RFSNMNQEQR-----TD- 227
                 NV+  +  +  FL     T+G D++            FS+ + +QR     TD 
Sbjct: 199 KLFFITNVIIQVNLVCKFLDVDSWTWGFDLLGKFIHPTPRAPEFSSFSDKQRFAAILTDG 258

Query: 228 --PMIEVFPRITKCTFHKFGASGTIQKHDALCVLALNILNEK 267
                + FP +  C +    +      H A C++ +N++NEK
Sbjct: 259 SYNRFQYFPILVGCEYQLQESVSNFVNHKAQCIIPMNVINEK 300


>UniRef50_Q2L6M4 Cluster: Innexin11; n=2; Dugesiidae|Rep: Innexin11
           - Dugesia japonica (Planarian)
          Length = 438

 Score = 51.6 bits (118), Expect = 3e-05
 Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 7/116 (6%)

Query: 22  KAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGA----NPGHVINTFCWI 77
           +A + +   RM   +T  ILF+   LV        P+ C S  A    N    I ++CW+
Sbjct: 15  RAHLQDFADRMCSTVTVIILFIFSTLVAYKTYFISPMECFSTDAPNIQNLDKYITSYCWV 74

Query: 78  TYTFTMPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKNW 133
             T  +     K        D    K I+ YY W+P +L  Q   FY+P+ IW+ +
Sbjct: 75  EGTVDL--AADKRTPTDNEWDTMKLKSIN-YYPWIPIILGIQCAFFYLPNLIWREY 127


>UniRef50_O61788 Cluster: Innexin-17; n=3; Caenorhabditis|Rep:
           Innexin-17 - Caenorhabditis elegans
          Length = 362

 Score = 51.6 bits (118), Expect = 3e-05
 Identities = 58/253 (22%), Positives = 101/253 (39%), Gaps = 26/253 (10%)

Query: 31  RMHYRITSAILFLCCILVTANNLIGEPIACISDGANPG---HVINTFCWITYTFTMPNTT 87
           R+ Y  T  +L      + A   +G+ I C +     G       ++C I  T+ +    
Sbjct: 23  RLRYYFTVFLLTSSAFFIMAKQYVGQSIQCWAPKQFKGGWEEYAESYCLIENTYYVHMNN 82

Query: 88  SKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKNWEE--G-KVRLISEG 144
           S     P + ++ + K    YYQWVPF+LF   ++ YIP  IW   +   G  + +++  
Sbjct: 83  SNLPG-PAIRENKELK----YYQWVPFILFGLAVVIYIPRVIWNALQSLIGINISIVTSN 137

Query: 145 MRGTMAS--------IADDKNNRQ--NRLVQYLLDTLHMHNTYSFGYFFCEVLNFANVVG 194
           +R    S        I   K   Q   +     +D     +  +      + L    +  
Sbjct: 138 LRKVAKSGFTSENPDIEKKKKEMQCKKKATSRQVDGEFWGSRLTTCILATKFLATILIFI 197

Query: 195 NIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFGASGTIQKHD 254
           ++ FLD F+G   + YG  + +     ++ +       FPR+T C F +    G +    
Sbjct: 198 SMGFLDYFMGLGPM-YGWTITKDILQGRQWQESGS---FPRVTFCDF-QVRELGYVNNWS 252

Query: 255 ALCVLALNILNEK 267
             CVL +N+ NEK
Sbjct: 253 LQCVLMVNMFNEK 265


>UniRef50_Q38HR3 Cluster: Innexin 8; n=1; Hirudo medicinalis|Rep:
           Innexin 8 - Hirudo medicinalis (Medicinal leech)
          Length = 221

 Score = 50.4 bits (115), Expect = 8e-05
 Identities = 37/129 (28%), Positives = 57/129 (44%), Gaps = 4/129 (3%)

Query: 181 YFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTD-VVRFSNMNQEQRTDPMIEVFPRITKC 239
           +   +VL  ANV+  +  L   LG  + T+G D ++R+ + N     D  I  FPR+T C
Sbjct: 11  FLVSKVLYIANVIFQLITLSYVLGFKYSTFGIDMMIRYLHPNDWTEED--IVAFPRVTLC 68

Query: 240 TFHKFGAS-GTIQKHDALCVLALNILNEKXXXXXXXXXXXXSVVSGLALVYSAAVCLLPS 298
            F   G     +Q +   CVL +N++NEK            + +S L L    A  L   
Sbjct: 69  DFRIRGQDFHNVQNNTVECVLPVNMVNEKIFVFLWFWMVTVAFLSSLNLFVWMARALYHG 128

Query: 299 TRETILKRR 307
            R   ++ R
Sbjct: 129 DRLKFIQNR 137


>UniRef50_Q2VTE9 Cluster: Pannexin 6; n=1; Aplysia californica|Rep:
           Pannexin 6 - Aplysia californica (California sea hare)
          Length = 424

 Score = 50.4 bits (115), Expect = 8e-05
 Identities = 34/93 (36%), Positives = 46/93 (49%), Gaps = 5/93 (5%)

Query: 176 TYSFG-YFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFP 234
           TY  G Y F ++L F NV+G  F L  FL   F  +G D   F+  N++ R   +   FP
Sbjct: 202 TYISGLYMFTKLLYFVNVIGQFFLLSAFLDLNFWRFGIDA--FTIWNKKGRWQDLYN-FP 258

Query: 235 RITKCTFHKFGASGTIQKHDALCVLALNILNEK 267
           RI  C + K      IQ     CVL++N+  EK
Sbjct: 259 RIGLCDY-KVRQLENIQTLSVQCVLSINLFLEK 290


>UniRef50_Q2VTF0 Cluster: Pannexin 5; n=1; Aplysia californica|Rep:
           Pannexin 5 - Aplysia californica (California sea hare)
          Length = 406

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 8/109 (7%)

Query: 26  DNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGH---VINTFCWITYTFT 82
           D+ V + H+  + AI      L+  N  +G+PI C      P H        CWI+  + 
Sbjct: 21  DDAVDQFHHFASVAIFAASAALIGMNQYVGDPIHCWVPAQFPDHHQDYAENLCWISQMYY 80

Query: 83  MPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWK 131
           +P         P   DD  +  I S+Y+WV  +   Q LLF  P+ +W+
Sbjct: 81  VPMDEEI----PFYKDDRMKWDI-SFYRWVVAIFLIQCLLFKFPNMLWR 124



 Score = 43.2 bits (97), Expect = 0.012
 Identities = 30/93 (32%), Positives = 43/93 (46%), Gaps = 7/93 (7%)

Query: 176 TYSFG-YFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFP 234
           TY  G Y F ++L   NV+G    L  FL   +  YG +V++             IE FP
Sbjct: 199 TYLTGLYLFTKLLYLVNVIGQFVMLTAFLKFNYWWYGFEVLQHLGGRWVD-----IEHFP 253

Query: 235 RITKCTFHKFGASGTIQKHDALCVLALNILNEK 267
           R+  C F +      IQ +   CVL++N+  EK
Sbjct: 254 RVVMCDF-EIRQLQNIQTYSLQCVLSINLFIEK 285


>UniRef50_UPI00015B4966 Cluster: PREDICTED: similar to
           ENSANGP00000011556; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000011556 - Nasonia
           vitripennis
          Length = 212

 Score = 47.2 bits (107), Expect = 7e-04
 Identities = 37/126 (29%), Positives = 50/126 (39%), Gaps = 25/126 (19%)

Query: 18  YLIDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHVINTFCWI 77
           + + K   D  V R+H  +T+ +L     +V+    +G PI C+     P    N +CWI
Sbjct: 84  FQVSKVQNDGFVSRLHV-LTAVLLLTFSAMVSMKQAVGNPIDCVHTRDIPVEAFNAYCWI 142

Query: 78  --TY--TFTMPNTTSKTAAHPGLGDD---NDEKRIHS-----------------YYQWVP 113
             TY  T  M        A PG+G         R+ S                 YYQWVP
Sbjct: 143 HSTYFVTGAMLGVAGVNVAFPGVGSTLLFQHRPRLPSQQSADRGAADSLTRQVKYYQWVP 202

Query: 114 FMLFFQ 119
           F L FQ
Sbjct: 203 FFLVFQ 208


>UniRef50_Q21123 Cluster: Innexin-7; n=2; Caenorhabditis|Rep:
           Innexin-7 - Caenorhabditis elegans
          Length = 556

 Score = 47.2 bits (107), Expect = 7e-04
 Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 27/169 (15%)

Query: 27  NMVFRMHYRITSAILFLCCILVTANNLIGEPIACIS--DGANPG-HVINTFCWITYTFTM 83
           ++V  +H  +TS +L    +L++     G PI C+   D  +      N +CW   T+ +
Sbjct: 20  DLVASIHSFLTSNLLVGLAVLISWKQFGGTPIECMVPLDFTSAWVQYSNNYCWAQPTYFI 79

Query: 84  PNTTS--KTAAHPG--------LGDDNDEKRIH-------SYYQWVPFMLFFQGLLFYIP 126
           P T    +    P         +G+  +  R         SYYQW+ F L F+   F +P
Sbjct: 80  PFTEELVEQVVDPADVVADGITIGNGGNRPRFVKKGGEKISYYQWMSFFLLFEAACFRLP 139

Query: 127 HWIWKNWEEGKVRLISEGMR-GTMASIADDKNNRQNRLVQYLLDTLHMH 174
            +IWK +          GM+ G +  +A D+NN    + +  +D L +H
Sbjct: 140 CFIWKYFAS------QSGMQVGEILRVASDENNAVPLVKKANIDALCIH 182



 Score = 36.7 bits (81), Expect = 1.0
 Identities = 17/36 (47%), Positives = 20/36 (55%), Gaps = 1/36 (2%)

Query: 232 VFPRITKCTFHKFGASGTIQKHDALCVLALNILNEK 267
           VFPR+T C F      G +Q H   CVL LN+  EK
Sbjct: 275 VFPRVTLCDFETRDM-GNVQMHTVQCVLLLNLFTEK 309


>UniRef50_Q5D8R4 Cluster: SJCHGC06704 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC06704 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 134

 Score = 46.4 bits (105), Expect = 0.001
 Identities = 30/110 (27%), Positives = 50/110 (45%), Gaps = 6/110 (5%)

Query: 25  IDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHVINTF----CWITYT 80
           ++++  R+++  + AI+ +   +  AN     PIAC    A P +  N F    CW+  T
Sbjct: 24  LEDLADRLNHFFSCAIILMLSGVTMANVYFLRPIACTLPTA-PENKFNEFAESVCWVRGT 82

Query: 81  FTMPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIW 130
             + +               D+  + S+YQWVPF L  QG+LF     +W
Sbjct: 83  VAIRDNDQMPITDEDWEKLRDKADM-SFYQWVPFCLSIQGMLFLFTGNLW 131


>UniRef50_UPI0000DB719F Cluster: PREDICTED: similar to Innexin
           shaking-B (Protein passover); n=1; Apis mellifera|Rep:
           PREDICTED: similar to Innexin shaking-B (Protein
           passover) - Apis mellifera
          Length = 249

 Score = 46.0 bits (104), Expect = 0.002
 Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 20/119 (16%)

Query: 20  IDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHVINTFCWI-- 77
           ++K   D++  R+H  +T+ ++ +   ++++  ++G PI C+     P    N++CWI  
Sbjct: 79  MNKTKTDSITIRLH-SLTTILILMFSAIISSKQVVGNPIECVHTRDIPVEAFNSYCWIHS 137

Query: 78  TY--TFTMPNTTSKTAAHPGLG--------DDNDE-------KRIHSYYQWVPFMLFFQ 119
           TY  T  M  T       PG+         D  D+        +   YYQWV F+L  Q
Sbjct: 138 TYFVTRAMLGTNGIDVVAPGVAPSHGNHHYDQKDDISSNKETTKNVKYYQWVVFVLILQ 196


>UniRef50_Q2EMV6 Cluster: Innexin 1; n=1; Hydra vulgaris|Rep:
           Innexin 1 - Hydra attenuata (Hydra) (Hydra vulgaris)
          Length = 396

 Score = 42.3 bits (95), Expect = 0.021
 Identities = 42/199 (21%), Positives = 80/199 (40%), Gaps = 17/199 (8%)

Query: 102 EKRIHSYYQWVPFMLFFQGLLFYIPHWIWKNWEEGKVRLISEGMRGTMASIADDKNNRQN 161
           +K     YQW+PF++    +L+Y+P+  +++     + L +    GT    A+ +   +N
Sbjct: 127 QKTFFLQYQWMPFLIAALSILYYLPYIGFRSANSDLISLKNTIKGGT----ANAEKIAKN 182

Query: 162 RLVQYLLDTLHMHNTYSFGYFFCEVLNFANVVGNIFFLDTFLGGAFLTYGT--------- 212
              ++   + +M     F      +   AN+V     LD  L G F++YG+         
Sbjct: 183 FFDRHSNPSRNMTLRVVFNILIKVLYIVANLVA-FLGLDNLLNGEFVSYGSKWVSWAKLD 241

Query: 213 DVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFGAS---GTIQKHDALCVLALNILNEKXX 269
           + V +  M +  +  P   + P    C  ++        T  KH  +C L+ NIL +   
Sbjct: 242 NAVAYDYMGKYDQPKPGNVLLPPFGYCEMYESSKDIKHSTANKHKLICELSQNILYQYSL 301

Query: 270 XXXXXXXXXXSVVSGLALV 288
                      V+S + L+
Sbjct: 302 VIVWFAIVFGIVISVIGLI 320


>UniRef50_Q27295 Cluster: Innexin eat-5; n=2; Caenorhabditis|Rep:
           Innexin eat-5 - Caenorhabditis elegans
          Length = 423

 Score = 42.3 bits (95), Expect = 0.021
 Identities = 51/265 (19%), Positives = 112/265 (42%), Gaps = 38/265 (14%)

Query: 31  RMHYRITSAILFLCCILVTANNLIGEPIACISDGANPG---HVINTFCWITYTFTM-PNT 86
           R++Y  ++ I+    + +TA   +G P+ C                +C++  T+ + PN 
Sbjct: 22  RLNYYYSTLIIMGMSLTITARQYVGSPLQCWVPAQFTKAWEQYAEDYCFVYNTYWVKPND 81

Query: 87  TSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIP--HWIWKNWEEGK--VRLIS 142
                  P   ++   +++  YYQW PF++  +   FY+P   W   + + G   ++L+ 
Sbjct: 82  KV-----PLTVEERVSQQL-IYYQWAPFIMAIEAAFFYLPVIFWSMLSTKSGINIIKLVE 135

Query: 143 EGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYSFGYFFCEV-----LNFANVVGNIF 197
              +   A  ++++  + + + +++ + L             ++     +     + N++
Sbjct: 136 TAQKAEGAE-SEERKKQIDIICRHISNNLRKRRNEEETTKMAKIQRIFGMQHGKYITNVY 194

Query: 198 FLDT--FLGGAFLT-YGTDVVRFSNMNQE----QRTDPMIEV--------FPRITKCTFH 242
            +    ++  +FL  Y T+  +F   N      +  D +++         FPRI  C F 
Sbjct: 195 LVTKLIYMTNSFLQFYSTN--KFLGQNDPYWGMRILDDILKGTDWEHSGNFPRIAMCDF- 251

Query: 243 KFGASGTIQKHDALCVLALNILNEK 267
           +    G +Q++   CVL LN+ NEK
Sbjct: 252 QVRVLGNLQRYSIQCVLTLNMFNEK 276


>UniRef50_Q61ER8 Cluster: Putative uncharacterized protein CBG11965;
           n=1; Caenorhabditis briggsae|Rep: Putative
           uncharacterized protein CBG11965 - Caenorhabditis
           briggsae
          Length = 521

 Score = 38.3 bits (85), Expect = 0.34
 Identities = 25/103 (24%), Positives = 41/103 (39%), Gaps = 2/103 (1%)

Query: 31  RMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHVINTFCWITYTFTMPNTTSKT 90
           ++ +  T +IL     L+ +  L G PI+C      P   I  F    Y       +  T
Sbjct: 25  KLLHNTTISILIFLFFLLASKPLFGTPISCQLPKEWPESSIQYFADFCYYAKRDKVSFAT 84

Query: 91  AAHPGLGDDNDEKRIHS--YYQWVPFMLFFQGLLFYIPHWIWK 131
            +    G  +  K   +  +Y WVP +    G+L  +P + WK
Sbjct: 85  RSIGSQGTISHNKLTGTSDFYMWVPLVPILHGILTLLPVFFWK 127


>UniRef50_A2ESC5 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 1486

 Score = 35.5 bits (78), Expect = 2.4
 Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 3/77 (3%)

Query: 66  NPGHVINTFCWIT-YTFTMPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFY 124
           N G + +TFC IT Y     N     A     G+ N++  IHS+     ++L + G++ Y
Sbjct: 468 NLGQIYSTFCEITHYNTETENNNLTYALVSRSGNRNEDSNIHSH--CTQYILVYIGIILY 525

Query: 125 IPHWIWKNWEEGKVRLI 141
             +     W + +V+ I
Sbjct: 526 TFNLAMNGWAKSEVKSI 542


>UniRef50_P96742 Cluster: YwtG protein; n=5; Bacillales|Rep: YwtG
           protein - Bacillus subtilis
          Length = 457

 Score = 34.7 bits (76), Expect = 4.1
 Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 2/39 (5%)

Query: 112 VPFMLFFQGLLFY--IPHWIWKNWEEGKVRLISEGMRGT 148
           VP +L   G+LF    P W++ N EE K + I E +RGT
Sbjct: 170 VPSLLLLIGILFMPESPRWLFTNGEESKAKKILEKLRGT 208


>UniRef50_Q7SFU1 Cluster: Putative uncharacterized protein
           NCU00789.1; n=3; Pezizomycotina|Rep: Putative
           uncharacterized protein NCU00789.1 - Neurospora crassa
          Length = 930

 Score = 34.3 bits (75), Expect = 5.5
 Identities = 35/142 (24%), Positives = 58/142 (40%), Gaps = 10/142 (7%)

Query: 14  VKVRYLIDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPI-ACISDGANPGHVIN 72
           V  R ++  A +D  VF   +++   +  +      A   + EPI     D  N   V  
Sbjct: 89  VTERQVLASAGLDAYVFLNFFKMAMKLFVIIFFFALA---VLEPINRAFPDDLNTSEVPP 145

Query: 73  TFCWITYTFTMPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKN 132
           T  +  YT+   +TT      P   DD+ +K     + ++ F  FF GL  ++      N
Sbjct: 146 TQVFRQYTYPYGHTTLYDD-DPDQPDDSFKKSKRYLWSYLVFTYFFTGLTLFL-----MN 199

Query: 133 WEEGKVRLISEGMRGTMASIAD 154
            E  KV  + +   GT ++I D
Sbjct: 200 RETFKVLRVRQDYLGTQSTITD 221


>UniRef50_A7ASB1 Cluster: Putative uncharacterized protein; n=1;
           Babesia bovis|Rep: Putative uncharacterized protein -
           Babesia bovis
          Length = 1104

 Score = 33.5 bits (73), Expect = 9.5
 Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 3/64 (4%)

Query: 8   SSVAGFVKVRYLIDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIAC-ISDGAN 66
           +SV+  ++  +L D  V+D   + + YR+T    FL  + +  N + G P    ISD   
Sbjct: 96  NSVSDALENNFLWDVCVVDGQTYNVRYRVTRQGTFLLHVTLDGNPIPGSPFKIYISDA-- 153

Query: 67  PGHV 70
           P HV
Sbjct: 154 PPHV 157


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.326    0.140    0.432 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 421,547,469
Number of Sequences: 1657284
Number of extensions: 17133245
Number of successful extensions: 44078
Number of sequences better than 10.0: 83
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 43805
Number of HSP's gapped (non-prelim): 133
length of query: 385
length of database: 575,637,011
effective HSP length: 102
effective length of query: 283
effective length of database: 406,594,043
effective search space: 115066114169
effective search space used: 115066114169
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.6 bits)
S2: 73 (33.5 bits)

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