Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000442-TA|BGIBMGA000442-PA|IPR000863|Sulfotransferase
(825 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U36601-1|AAC27120.1| 883|Homo sapiens heparan N-deacetylase/N-s... 914 0.0
BC110589-1|AAI10590.1| 883|Homo sapiens N-deacetylase/N-sulfotr... 914 0.0
BC110588-1|AAI10589.1| 883|Homo sapiens N-deacetylase/N-sulfotr... 914 0.0
BC035711-1|AAH35711.1| 883|Homo sapiens N-deacetylase/N-sulfotr... 914 0.0
AF042084-1|AAB97086.1| 883|Homo sapiens heparan glucosaminyl N-... 914 0.0
U36600-1|AAC27354.1| 882|Homo sapiens heparan N-deacetylase/N-s... 890 0.0
U18918-1|AAA75281.1| 882|Homo sapiens heparan sulfate-N-deacety... 890 0.0
U17970-1|AAA67765.1| 882|Homo sapiens heparan sulfate N-deacety... 887 0.0
BC109310-1|AAI09311.1| 873|Homo sapiens N-deacetylase/N-sulfotr... 869 0.0
BC109309-1|AAI09310.1| 873|Homo sapiens N-deacetylase/N-sulfotr... 869 0.0
AF076605-1|AAD46061.1| 876|Homo sapiens heparan N-deacetylase/N... 869 0.0
AF074924-1|AAD15978.1| 873|Homo sapiens heparan sulfate N-deace... 869 0.0
AB036429-1|BAB18535.1| 872|Homo sapiens N-deacetylase/N-sulfotr... 861 0.0
AB209107-1|BAD92344.1| 698|Homo sapiens N-deacetylase/N-sulfotr... 792 0.0
BC012888-1|AAH12888.1| 556|Homo sapiens NDST1 protein protein. 505 e-142
BC113075-1|AAI13076.1| 369|Homo sapiens NDST4 protein protein. 488 e-137
AB208870-1|BAD92107.1| 364|Homo sapiens N-deacetylase/N-sulfotr... 279 3e-74
AC108201-1|AAY41001.1| 356|Homo sapiens unknown protein. 259 2e-68
AC110999-1|AAY41056.1| 156|Homo sapiens unknown protein. 242 3e-63
AY358852-1|AAQ89211.1| 385|Homo sapiens HSS3 protein. 230 2e-59
BC093913-1|AAH93913.1| 346|Homo sapiens heparan sulfate (glucos... 105 6e-22
BC093911-1|AAH93911.1| 346|Homo sapiens heparan sulfate (glucos... 105 6e-22
AF503292-1|AAN37737.1| 346|Homo sapiens heparan sulfate 3-OST-5... 105 6e-22
BC057803-1|AAH57803.1| 307|Homo sapiens heparan sulfate (glucos... 96 4e-19
AF019386-1|AAB84388.1| 307|Homo sapiens heparan sulfate 3-O-sul... 96 5e-19
BC093736-1|AAH93736.1| 367|Homo sapiens heparan sulfate D-gluco... 95 9e-19
BC093734-1|AAH93734.1| 367|Homo sapiens heparan sulfate (glucos... 95 9e-19
AY359095-1|AAQ89453.1| 367|Homo sapiens HS3ST2 protein. 95 9e-19
AF105375-1|AAD30207.1| 367|Homo sapiens heparan sulfate D-gluco... 95 9e-19
AF105374-1|AAD30206.1| 367|Homo sapiens heparan sulfate D-gluco... 95 9e-19
AB209794-1|BAD93031.1| 345|Homo sapiens heparan sulfate D-gluco... 95 9e-19
AL834283-1|CAD38957.1| 335|Homo sapiens hypothetical protein pr... 92 6e-18
AF105378-1|AAD30210.2| 456|Homo sapiens heparan sulfate 3-O-sul... 92 6e-18
BC069725-1|AAH69725.1| 390|Homo sapiens heparan sulfate D-gluco... 91 1e-17
BC069664-1|AAH69664.1| 390|Homo sapiens heparan sulfate (glucos... 91 1e-17
BC063301-1|AAH63301.1| 390|Homo sapiens heparan sulfate (glucos... 91 1e-17
BC044647-1|AAH44647.1| 406|Homo sapiens heparan sulfate (glucos... 91 1e-17
AY358838-1|AAQ89197.1| 406|Homo sapiens HS3ST3A1 protein. 91 1e-17
AF105377-1|AAD30209.1| 390|Homo sapiens heparan sulfate D-gluco... 91 1e-17
AF105376-1|AAD30208.1| 406|Homo sapiens heparan sulfate D-gluco... 91 1e-17
AL031723-1|CAC42157.1| 381|Homo sapiens protein ( Human DNA seq... 86 6e-16
AE006640-3|AAK61299.1| 311|Homo sapiens heparan sulphate D-gluc... 86 6e-16
EF063608-1|ABN79919.1| 139|Homo sapiens heparan sulfate 3-O-sul... 73 6e-12
EF063607-1|ABN79918.1| 139|Homo sapiens heparan sulfate 3-O-sul... 73 6e-12
EF063606-1|ABN79917.1| 139|Homo sapiens heparan sulfate 3-O-sul... 73 6e-12
EF063605-1|ABN79916.1| 139|Homo sapiens heparan sulfate 3-O-sul... 73 6e-12
EF063604-1|ABN79915.1| 139|Homo sapiens heparan sulfate 3-O-sul... 73 6e-12
EF063603-1|ABN79914.1| 139|Homo sapiens heparan sulfate 3-O-sul... 73 6e-12
EF063602-1|ABN79913.1| 139|Homo sapiens heparan sulfate 3-O-sul... 73 6e-12
EF063601-1|ABN79912.1| 139|Homo sapiens heparan sulfate 3-O-sul... 73 6e-12
AK091074-1|BAC03577.1| 175|Homo sapiens protein ( Homo sapiens ... 53 5e-06
AY476736-1|AAS58324.1| 244|Homo sapiens heparan sulfate 3-O-sul... 38 0.19
M73240-1|AAA64297.1| 723|Homo sapiens hepatocyte growth factor ... 32 9.5
M73239-1|AAA64239.1| 728|Homo sapiens hepatocyte growth factor ... 32 9.5
M60718-1|AAA52648.1| 728|Homo sapiens hepatocyte growth factor ... 32 9.5
M29145-1|AAA52650.1| 728|Homo sapiens HGF protein. 32 9.5
D90334-1|BAA14348.1| 728|Homo sapiens hepatocyte growth factor ... 32 9.5
BC130286-1|AAI30287.1| 728|Homo sapiens hepatocyte growth facto... 32 9.5
BC130284-1|AAI30285.1| 728|Homo sapiens hepatocyte growth facto... 32 9.5
AY246560-1|AAO61091.1| 728|Homo sapiens hepatocyte growth facto... 32 9.5
AC004960-1|AAC71655.1| 723|Homo sapiens hepatocyte growth facto... 32 9.5
>U36601-1|AAC27120.1| 883|Homo sapiens heparan
N-deacetylase/N-sulfotransferase-2 protein.
Length = 883
Score = 914 bits (2261), Expect = 0.0
Identities = 409/696 (58%), Positives = 527/696 (75%), Gaps = 6/696 (0%)
Query: 11 YKIEVA-GKS-LPVLTTLDKGRYGVIVFESLSKYANMDKWNRELLDKYCREYSVGVVGFA 68
Y E+A G+ +P LT GRY ++++E+L KY N+D W+RELLD+YC EY VG++GF
Sbjct: 113 YSTELAPGRGDMPTLTDNTHGRYVLVIYENLLKYVNLDAWSRELLDRYCVEYGVGIIGFF 172
Query: 69 TPSEETLVGAQLKGFPLFMHTNLRLKDATLNAASPVLRLARAGETAWGALPGDHWSVFRA 128
E +L+ AQLKGFPLF+H+NL L+D +N ++P+L L R G LPGD W++F++
Sbjct: 173 RAHEHSLLSAQLKGFPLFLHSNLGLRDYQVNPSAPLLHLTRPSRLEPGPLPGDDWTIFQS 232
Query: 129 NSSTYEPIAWA-LREHDYETDG---ERMPLATVIQDHGRLDGVQRVLFGSGLQFWLHRLL 184
N STYEP+ A LR + G R L TV+QD G DG+QRVLFG GL FWLH+L+
Sbjct: 233 NHSTYEPVLLASLRPAEPAVPGPVLRRARLPTVVQDLGLHDGIQRVLFGHGLSFWLHKLI 292
Query: 185 FLDALSYLSHGQLSLSLDRWILVDIDDIFVGEKGTRLHEEDVAALLTSQAALQRLVPGFR 244
F+DA++YL+ +L L LDR+ILVDIDDIFVG++GTR+ DV ALLT+Q L+ LVP F
Sbjct: 293 FVDAVAYLTGKRLCLDLDRYILVDIDDIFVGKEGTRMKVADVEALLTTQNKLRTLVPNFT 352
Query: 245 FNLGYSAKYYHHGTPTENLGDDALLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMMLNK 304
FNLG+S K+YH GT E+ GDD LLKHR+ F WF HMW+H QPHL++N S L +M LNK
Sbjct: 353 FNLGFSGKFYHTGTEEEDAGDDMLLKHRKEFWWFPHMWSHMQPHLFHNRSVLADQMRLNK 412
Query: 305 QFALEHGIPTNSCYSVSPHHSGVYPVHEPLYEAWRKVWDVKVTSTEEYPHLRPARLRRGF 364
QFALEHGIPT+ Y+V+PHHSGVYP+H LYEAW+ VW ++VTSTEEYPHLRPAR RRGF
Sbjct: 413 QFALEHGIPTDLGYAVAPHHSGVYPIHTQLYEAWKSVWGIQVTSTEEYPHLRPARYRRGF 472
Query: 365 RHRGVMVLPRQTCGLFTHTLLLERYPGGRHRLDRSIQGGELFQTVINNPINVFMTHMSNY 424
H G+MVLPRQTCGLFTHT+ YPGG LDRSI+GGELF TV+ NPI++FMTH+SNY
Sbjct: 473 IHNGIMVLPRQTCGLFTHTIFYNEYPGGSRELDRSIRGGELFLTVLLNPISIFMTHLSNY 532
Query: 425 GNDRLALYTFESVVKFLRCWTNVRLASAPPLALAEKYFQLRPDELNPLWGNPCDDIRHRR 484
GNDRL LYTFES+V+FL+CWT +RL + PP+ LA+KYF+L P E +PLW NPCDD RH+
Sbjct: 533 GNDRLGLYTFESLVRFLQCWTRLRLQTLPPVPLAQKYFELFPQERSPLWQNPCDDKRHKD 592
Query: 485 IWSKSKWCGTLPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLK 544
IWSK K C LP+ L++GPQKTG+TA++ FL++HP + + PSPST+EE+QFFN+ NY K
Sbjct: 593 IWSKEKTCDRLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHK 652
Query: 545 GLDWYLNFFPPSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSW 604
G+DWY++FFP ++ FEKSATYFD ++VPRR ALLP AKII +L +P+ RAYSW
Sbjct: 653 GIDWYMDFFPVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSW 712
Query: 605 YQHIRSHGDPIANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQL 664
YQH R+HGDP+A NYTF+ +I+A+ P LR L+NRCL PG YS +L+RWL+ Y QL
Sbjct: 713 YQHQRAHGDPVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQL 772
Query: 665 HVIDGSMLRSEPAVVMNTLQKFLKISPHIDYNKLLK 700
++DG LR+ PA M ++QKFL I+P ++Y + L+
Sbjct: 773 LIVDGQELRTNPAASMESIQKFLGITPFLNYTRTLR 808
Score = 75.8 bits (178), Expect = 6e-13
Identities = 40/80 (50%), Positives = 52/80 (65%), Gaps = 3/80 (3%)
Query: 742 INNVRTRFAFNDDADLKAPKELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHNTA 801
+N RT F+DD + L GG KT+CLG+SKGR YP M+ S FL ++ HN
Sbjct: 801 LNYTRT-LRFDDDKGFWC-QGLEGG-KTRCLGRSKGRRYPDMDTESRLFLTDFFRNHNLE 857
Query: 802 LSKLLVRVGRPVPHWLKDEL 821
LSKLL R+G+PVP WL++EL
Sbjct: 858 LSKLLSRLGQPVPSWLREEL 877
>BC110589-1|AAI10590.1| 883|Homo sapiens
N-deacetylase/N-sulfotransferase (heparan glucosaminyl)
2 protein.
Length = 883
Score = 914 bits (2261), Expect = 0.0
Identities = 409/696 (58%), Positives = 527/696 (75%), Gaps = 6/696 (0%)
Query: 11 YKIEVA-GKS-LPVLTTLDKGRYGVIVFESLSKYANMDKWNRELLDKYCREYSVGVVGFA 68
Y E+A G+ +P LT GRY ++++E+L KY N+D W+RELLD+YC EY VG++GF
Sbjct: 113 YSTELAPGRGDMPTLTDNTHGRYVLVIYENLLKYVNLDAWSRELLDRYCVEYGVGIIGFF 172
Query: 69 TPSEETLVGAQLKGFPLFMHTNLRLKDATLNAASPVLRLARAGETAWGALPGDHWSVFRA 128
E +L+ AQLKGFPLF+H+NL L+D +N ++P+L L R G LPGD W++F++
Sbjct: 173 RAHEHSLLSAQLKGFPLFLHSNLGLRDYQVNPSAPLLHLTRPSRLEPGPLPGDDWTIFQS 232
Query: 129 NSSTYEPIAWA-LREHDYETDG---ERMPLATVIQDHGRLDGVQRVLFGSGLQFWLHRLL 184
N STYEP+ A LR + G R L TV+QD G DG+QRVLFG GL FWLH+L+
Sbjct: 233 NHSTYEPVLLASLRPAEPAVPGPVLRRARLPTVVQDLGLHDGIQRVLFGHGLSFWLHKLI 292
Query: 185 FLDALSYLSHGQLSLSLDRWILVDIDDIFVGEKGTRLHEEDVAALLTSQAALQRLVPGFR 244
F+DA++YL+ +L L LDR+ILVDIDDIFVG++GTR+ DV ALLT+Q L+ LVP F
Sbjct: 293 FVDAVAYLTGKRLCLDLDRYILVDIDDIFVGKEGTRMKVADVEALLTTQNKLRTLVPNFT 352
Query: 245 FNLGYSAKYYHHGTPTENLGDDALLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMMLNK 304
FNLG+S K+YH GT E+ GDD LLKHR+ F WF HMW+H QPHL++N S L +M LNK
Sbjct: 353 FNLGFSGKFYHTGTEEEDAGDDMLLKHRKEFWWFPHMWSHMQPHLFHNRSVLADQMRLNK 412
Query: 305 QFALEHGIPTNSCYSVSPHHSGVYPVHEPLYEAWRKVWDVKVTSTEEYPHLRPARLRRGF 364
QFALEHGIPT+ Y+V+PHHSGVYP+H LYEAW+ VW ++VTSTEEYPHLRPAR RRGF
Sbjct: 413 QFALEHGIPTDLGYAVAPHHSGVYPIHTQLYEAWKSVWGIQVTSTEEYPHLRPARYRRGF 472
Query: 365 RHRGVMVLPRQTCGLFTHTLLLERYPGGRHRLDRSIQGGELFQTVINNPINVFMTHMSNY 424
H G+MVLPRQTCGLFTHT+ YPGG LDRSI+GGELF TV+ NPI++FMTH+SNY
Sbjct: 473 IHNGIMVLPRQTCGLFTHTIFYNEYPGGSRELDRSIRGGELFLTVLLNPISIFMTHLSNY 532
Query: 425 GNDRLALYTFESVVKFLRCWTNVRLASAPPLALAEKYFQLRPDELNPLWGNPCDDIRHRR 484
GNDRL LYTFES+V+FL+CWT +RL + PP+ LA+KYF+L P E +PLW NPCDD RH+
Sbjct: 533 GNDRLGLYTFESLVRFLQCWTRLRLQTLPPVPLAQKYFELFPQERSPLWQNPCDDKRHKD 592
Query: 485 IWSKSKWCGTLPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLK 544
IWSK K C LP+ L++GPQKTG+TA++ FL++HP + + PSPST+EE+QFFN+ NY K
Sbjct: 593 IWSKEKTCDRLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHK 652
Query: 545 GLDWYLNFFPPSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSW 604
G+DWY++FFP ++ FEKSATYFD ++VPRR ALLP AKII +L +P+ RAYSW
Sbjct: 653 GIDWYMDFFPVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSW 712
Query: 605 YQHIRSHGDPIANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQL 664
YQH R+HGDP+A NYTF+ +I+A+ P LR L+NRCL PG YS +L+RWL+ Y QL
Sbjct: 713 YQHQRAHGDPVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQL 772
Query: 665 HVIDGSMLRSEPAVVMNTLQKFLKISPHIDYNKLLK 700
++DG LR+ PA M ++QKFL I+P ++Y + L+
Sbjct: 773 LIVDGQELRTNPAASMESIQKFLGITPFLNYTRTLR 808
Score = 75.8 bits (178), Expect = 6e-13
Identities = 40/80 (50%), Positives = 52/80 (65%), Gaps = 3/80 (3%)
Query: 742 INNVRTRFAFNDDADLKAPKELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHNTA 801
+N RT F+DD + L GG KT+CLG+SKGR YP M+ S FL ++ HN
Sbjct: 801 LNYTRT-LRFDDDKGFWC-QGLEGG-KTRCLGRSKGRRYPDMDTESRLFLTDFFRNHNLE 857
Query: 802 LSKLLVRVGRPVPHWLKDEL 821
LSKLL R+G+PVP WL++EL
Sbjct: 858 LSKLLSRLGQPVPSWLREEL 877
>BC110588-1|AAI10589.1| 883|Homo sapiens
N-deacetylase/N-sulfotransferase (heparan glucosaminyl)
2 protein.
Length = 883
Score = 914 bits (2261), Expect = 0.0
Identities = 409/696 (58%), Positives = 527/696 (75%), Gaps = 6/696 (0%)
Query: 11 YKIEVA-GKS-LPVLTTLDKGRYGVIVFESLSKYANMDKWNRELLDKYCREYSVGVVGFA 68
Y E+A G+ +P LT GRY ++++E+L KY N+D W+RELLD+YC EY VG++GF
Sbjct: 113 YSTELAPGRGDMPTLTDNTHGRYVLVIYENLLKYVNLDAWSRELLDRYCVEYGVGIIGFF 172
Query: 69 TPSEETLVGAQLKGFPLFMHTNLRLKDATLNAASPVLRLARAGETAWGALPGDHWSVFRA 128
E +L+ AQLKGFPLF+H+NL L+D +N ++P+L L R G LPGD W++F++
Sbjct: 173 RAHEHSLLSAQLKGFPLFLHSNLGLRDYQVNPSAPLLHLTRPSRLEPGPLPGDDWTIFQS 232
Query: 129 NSSTYEPIAWA-LREHDYETDG---ERMPLATVIQDHGRLDGVQRVLFGSGLQFWLHRLL 184
N STYEP+ A LR + G R L TV+QD G DG+QRVLFG GL FWLH+L+
Sbjct: 233 NHSTYEPVLLASLRPAEPAVPGPVLRRARLPTVVQDLGLHDGIQRVLFGHGLSFWLHKLI 292
Query: 185 FLDALSYLSHGQLSLSLDRWILVDIDDIFVGEKGTRLHEEDVAALLTSQAALQRLVPGFR 244
F+DA++YL+ +L L LDR+ILVDIDDIFVG++GTR+ DV ALLT+Q L+ LVP F
Sbjct: 293 FVDAVAYLTGKRLCLDLDRYILVDIDDIFVGKEGTRMKVADVEALLTTQNKLRTLVPNFT 352
Query: 245 FNLGYSAKYYHHGTPTENLGDDALLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMMLNK 304
FNLG+S K+YH GT E+ GDD LLKHR+ F WF HMW+H QPHL++N S L +M LNK
Sbjct: 353 FNLGFSGKFYHTGTEEEDAGDDMLLKHRKEFWWFPHMWSHMQPHLFHNRSVLADQMRLNK 412
Query: 305 QFALEHGIPTNSCYSVSPHHSGVYPVHEPLYEAWRKVWDVKVTSTEEYPHLRPARLRRGF 364
QFALEHGIPT+ Y+V+PHHSGVYP+H LYEAW+ VW ++VTSTEEYPHLRPAR RRGF
Sbjct: 413 QFALEHGIPTDLGYAVAPHHSGVYPIHTQLYEAWKSVWGIQVTSTEEYPHLRPARYRRGF 472
Query: 365 RHRGVMVLPRQTCGLFTHTLLLERYPGGRHRLDRSIQGGELFQTVINNPINVFMTHMSNY 424
H G+MVLPRQTCGLFTHT+ YPGG LDRSI+GGELF TV+ NPI++FMTH+SNY
Sbjct: 473 IHNGIMVLPRQTCGLFTHTIFYNEYPGGSRELDRSIRGGELFLTVLLNPISIFMTHLSNY 532
Query: 425 GNDRLALYTFESVVKFLRCWTNVRLASAPPLALAEKYFQLRPDELNPLWGNPCDDIRHRR 484
GNDRL LYTFES+V+FL+CWT +RL + PP+ LA+KYF+L P E +PLW NPCDD RH+
Sbjct: 533 GNDRLGLYTFESLVRFLQCWTRLRLQTLPPVPLAQKYFELFPQERSPLWQNPCDDKRHKD 592
Query: 485 IWSKSKWCGTLPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLK 544
IWSK K C LP+ L++GPQKTG+TA++ FL++HP + + PSPST+EE+QFFN+ NY K
Sbjct: 593 IWSKEKTCDRLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHK 652
Query: 545 GLDWYLNFFPPSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSW 604
G+DWY++FFP ++ FEKSATYFD ++VPRR ALLP AKII +L +P+ RAYSW
Sbjct: 653 GIDWYMDFFPVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSW 712
Query: 605 YQHIRSHGDPIANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQL 664
YQH R+HGDP+A NYTF+ +I+A+ P LR L+NRCL PG YS +L+RWL+ Y QL
Sbjct: 713 YQHQRAHGDPVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQL 772
Query: 665 HVIDGSMLRSEPAVVMNTLQKFLKISPHIDYNKLLK 700
++DG LR+ PA M ++QKFL I+P ++Y + L+
Sbjct: 773 LIVDGQELRTNPAASMESIQKFLGITPFLNYTRTLR 808
Score = 75.8 bits (178), Expect = 6e-13
Identities = 40/80 (50%), Positives = 52/80 (65%), Gaps = 3/80 (3%)
Query: 742 INNVRTRFAFNDDADLKAPKELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHNTA 801
+N RT F+DD + L GG KT+CLG+SKGR YP M+ S FL ++ HN
Sbjct: 801 LNYTRT-LRFDDDKGFWC-QGLEGG-KTRCLGRSKGRRYPDMDTESRLFLTDFFRNHNLE 857
Query: 802 LSKLLVRVGRPVPHWLKDEL 821
LSKLL R+G+PVP WL++EL
Sbjct: 858 LSKLLSRLGQPVPSWLREEL 877
>BC035711-1|AAH35711.1| 883|Homo sapiens
N-deacetylase/N-sulfotransferase (heparan glucosaminyl)
2 protein.
Length = 883
Score = 914 bits (2261), Expect = 0.0
Identities = 409/696 (58%), Positives = 527/696 (75%), Gaps = 6/696 (0%)
Query: 11 YKIEVA-GKS-LPVLTTLDKGRYGVIVFESLSKYANMDKWNRELLDKYCREYSVGVVGFA 68
Y E+A G+ +P LT GRY ++++E+L KY N+D W+RELLD+YC EY VG++GF
Sbjct: 113 YSTELAPGRGDMPTLTDNTHGRYVLVIYENLLKYVNLDAWSRELLDRYCVEYGVGIIGFF 172
Query: 69 TPSEETLVGAQLKGFPLFMHTNLRLKDATLNAASPVLRLARAGETAWGALPGDHWSVFRA 128
E +L+ AQLKGFPLF+H+NL L+D +N ++P+L L R G LPGD W++F++
Sbjct: 173 RAHEHSLLSAQLKGFPLFLHSNLGLRDYQVNPSAPLLHLTRPSRLEPGPLPGDDWTIFQS 232
Query: 129 NSSTYEPIAWA-LREHDYETDG---ERMPLATVIQDHGRLDGVQRVLFGSGLQFWLHRLL 184
N STYEP+ A LR + G R L TV+QD G DG+QRVLFG GL FWLH+L+
Sbjct: 233 NHSTYEPVLLASLRPAEPAVPGPVLRRARLPTVVQDLGLHDGIQRVLFGHGLSFWLHKLI 292
Query: 185 FLDALSYLSHGQLSLSLDRWILVDIDDIFVGEKGTRLHEEDVAALLTSQAALQRLVPGFR 244
F+DA++YL+ +L L LDR+ILVDIDDIFVG++GTR+ DV ALLT+Q L+ LVP F
Sbjct: 293 FVDAVAYLTGKRLCLDLDRYILVDIDDIFVGKEGTRMKVADVEALLTTQNKLRTLVPNFT 352
Query: 245 FNLGYSAKYYHHGTPTENLGDDALLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMMLNK 304
FNLG+S K+YH GT E+ GDD LLKHR+ F WF HMW+H QPHL++N S L +M LNK
Sbjct: 353 FNLGFSGKFYHTGTEEEDAGDDMLLKHRKEFWWFPHMWSHMQPHLFHNRSVLADQMRLNK 412
Query: 305 QFALEHGIPTNSCYSVSPHHSGVYPVHEPLYEAWRKVWDVKVTSTEEYPHLRPARLRRGF 364
QFALEHGIPT+ Y+V+PHHSGVYP+H LYEAW+ VW ++VTSTEEYPHLRPAR RRGF
Sbjct: 413 QFALEHGIPTDLGYAVAPHHSGVYPIHTQLYEAWKSVWGIQVTSTEEYPHLRPARYRRGF 472
Query: 365 RHRGVMVLPRQTCGLFTHTLLLERYPGGRHRLDRSIQGGELFQTVINNPINVFMTHMSNY 424
H G+MVLPRQTCGLFTHT+ YPGG LDRSI+GGELF TV+ NPI++FMTH+SNY
Sbjct: 473 IHNGIMVLPRQTCGLFTHTIFYNEYPGGSRELDRSIRGGELFLTVLLNPISIFMTHLSNY 532
Query: 425 GNDRLALYTFESVVKFLRCWTNVRLASAPPLALAEKYFQLRPDELNPLWGNPCDDIRHRR 484
GNDRL LYTFES+V+FL+CWT +RL + PP+ LA+KYF+L P E +PLW NPCDD RH+
Sbjct: 533 GNDRLGLYTFESLVRFLQCWTRLRLQTLPPVPLAQKYFELFPQERSPLWQNPCDDKRHKD 592
Query: 485 IWSKSKWCGTLPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLK 544
IWSK K C LP+ L++GPQKTG+TA++ FL++HP + + PSPST+EE+QFFN+ NY K
Sbjct: 593 IWSKEKTCDRLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHK 652
Query: 545 GLDWYLNFFPPSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSW 604
G+DWY++FFP ++ FEKSATYFD ++VPRR ALLP AKII +L +P+ RAYSW
Sbjct: 653 GIDWYMDFFPVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSW 712
Query: 605 YQHIRSHGDPIANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQL 664
YQH R+HGDP+A NYTF+ +I+A+ P LR L+NRCL PG YS +L+RWL+ Y QL
Sbjct: 713 YQHQRAHGDPVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQL 772
Query: 665 HVIDGSMLRSEPAVVMNTLQKFLKISPHIDYNKLLK 700
++DG LR+ PA M ++QKFL I+P ++Y + L+
Sbjct: 773 LIVDGQELRTNPAASMESIQKFLGITPFLNYTRTLR 808
Score = 75.8 bits (178), Expect = 6e-13
Identities = 40/80 (50%), Positives = 52/80 (65%), Gaps = 3/80 (3%)
Query: 742 INNVRTRFAFNDDADLKAPKELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHNTA 801
+N RT F+DD + L GG KT+CLG+SKGR YP M+ S FL ++ HN
Sbjct: 801 LNYTRT-LRFDDDKGFWC-QGLEGG-KTRCLGRSKGRRYPDMDTESRLFLTDFFRNHNLE 857
Query: 802 LSKLLVRVGRPVPHWLKDEL 821
LSKLL R+G+PVP WL++EL
Sbjct: 858 LSKLLSRLGQPVPSWLREEL 877
>AF042084-1|AAB97086.1| 883|Homo sapiens heparan glucosaminyl
N-deacetylase/N-sulfotransferase-2 protein.
Length = 883
Score = 914 bits (2261), Expect = 0.0
Identities = 409/696 (58%), Positives = 527/696 (75%), Gaps = 6/696 (0%)
Query: 11 YKIEVA-GKS-LPVLTTLDKGRYGVIVFESLSKYANMDKWNRELLDKYCREYSVGVVGFA 68
Y E+A G+ +P LT GRY ++++E+L KY N+D W+RELLD+YC EY VG++GF
Sbjct: 113 YSTELAPGRGDMPTLTDNTHGRYVLVIYENLLKYVNLDAWSRELLDRYCVEYGVGIIGFF 172
Query: 69 TPSEETLVGAQLKGFPLFMHTNLRLKDATLNAASPVLRLARAGETAWGALPGDHWSVFRA 128
E +L+ AQLKGFPLF+H+NL L+D +N ++P+L L R G LPGD W++F++
Sbjct: 173 RAHEHSLLSAQLKGFPLFLHSNLGLRDYQVNPSAPLLHLTRPSRLEPGPLPGDDWTIFQS 232
Query: 129 NSSTYEPIAWA-LREHDYETDG---ERMPLATVIQDHGRLDGVQRVLFGSGLQFWLHRLL 184
N STYEP+ A LR + G R L TV+QD G DG+QRVLFG GL FWLH+L+
Sbjct: 233 NHSTYEPVLLASLRPAEPAVPGPVLRRARLPTVVQDLGLHDGIQRVLFGHGLSFWLHKLI 292
Query: 185 FLDALSYLSHGQLSLSLDRWILVDIDDIFVGEKGTRLHEEDVAALLTSQAALQRLVPGFR 244
F+DA++YL+ +L L LDR+ILVDIDDIFVG++GTR+ DV ALLT+Q L+ LVP F
Sbjct: 293 FVDAVAYLTGKRLCLDLDRYILVDIDDIFVGKEGTRMKVADVEALLTTQNKLRTLVPNFT 352
Query: 245 FNLGYSAKYYHHGTPTENLGDDALLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMMLNK 304
FNLG+S K+YH GT E+ GDD LLKHR+ F WF HMW+H QPHL++N S L +M LNK
Sbjct: 353 FNLGFSGKFYHTGTEEEDAGDDMLLKHRKEFWWFPHMWSHMQPHLFHNRSVLADQMRLNK 412
Query: 305 QFALEHGIPTNSCYSVSPHHSGVYPVHEPLYEAWRKVWDVKVTSTEEYPHLRPARLRRGF 364
QFALEHGIPT+ Y+V+PHHSGVYP+H LYEAW+ VW ++VTSTEEYPHLRPAR RRGF
Sbjct: 413 QFALEHGIPTDLGYAVAPHHSGVYPIHTQLYEAWKSVWGIQVTSTEEYPHLRPARYRRGF 472
Query: 365 RHRGVMVLPRQTCGLFTHTLLLERYPGGRHRLDRSIQGGELFQTVINNPINVFMTHMSNY 424
H G+MVLPRQTCGLFTHT+ YPGG LDRSI+GGELF TV+ NPI++FMTH+SNY
Sbjct: 473 IHNGIMVLPRQTCGLFTHTIFYNEYPGGSRELDRSIRGGELFLTVLLNPISIFMTHLSNY 532
Query: 425 GNDRLALYTFESVVKFLRCWTNVRLASAPPLALAEKYFQLRPDELNPLWGNPCDDIRHRR 484
GNDRL LYTFES+V+FL+CWT +RL + PP+ LA+KYF+L P E +PLW NPCDD RH+
Sbjct: 533 GNDRLGLYTFESLVRFLQCWTRLRLQTLPPVPLAQKYFELFPQERSPLWQNPCDDKRHKD 592
Query: 485 IWSKSKWCGTLPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLK 544
IWSK K C LP+ L++GPQKTG+TA++ FL++HP + + PSPST+EE+QFFN+ NY K
Sbjct: 593 IWSKEKTCDRLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHK 652
Query: 545 GLDWYLNFFPPSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSW 604
G+DWY++FFP ++ FEKSATYFD ++VPRR ALLP AKII +L +P+ RAYSW
Sbjct: 653 GIDWYMDFFPVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSW 712
Query: 605 YQHIRSHGDPIANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQL 664
YQH R+HGDP+A NYTF+ +I+A+ P LR L+NRCL PG YS +L+RWL+ Y QL
Sbjct: 713 YQHQRAHGDPVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQL 772
Query: 665 HVIDGSMLRSEPAVVMNTLQKFLKISPHIDYNKLLK 700
++DG LR+ PA M ++QKFL I+P ++Y + L+
Sbjct: 773 LIVDGQELRTNPAASMESIQKFLGITPFLNYTRTLR 808
Score = 75.8 bits (178), Expect = 6e-13
Identities = 40/80 (50%), Positives = 52/80 (65%), Gaps = 3/80 (3%)
Query: 742 INNVRTRFAFNDDADLKAPKELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHNTA 801
+N RT F+DD + L GG KT+CLG+SKGR YP M+ S FL ++ HN
Sbjct: 801 LNYTRT-LRFDDDKGFWC-QGLEGG-KTRCLGRSKGRRYPDMDTESRLFLTDFFRNHNLE 857
Query: 802 LSKLLVRVGRPVPHWLKDEL 821
LSKLL R+G+PVP WL++EL
Sbjct: 858 LSKLLSRLGQPVPSWLREEL 877
>U36600-1|AAC27354.1| 882|Homo sapiens heparan
N-deacetylase/N-sulfotransferase-1 protein.
Length = 882
Score = 890 bits (2201), Expect = 0.0
Identities = 402/698 (57%), Positives = 518/698 (74%), Gaps = 9/698 (1%)
Query: 11 YKIEVA-GKS-LPVLTTLDKGRYGVIVFESLSKYANMDKWNRELLDKYCREYSVGVVGFA 68
Y+ E+A GK +P LT +GR+ +I++E++ KY N+D WNRELLDKYC Y VG++GF
Sbjct: 111 YRTEIAPGKGDMPTLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFF 170
Query: 69 TPSEETLVGAQLKGFPLFMHTNLRLKDATLNAASPVLRLARAGETAWGALPGDHWSVFRA 128
+E +L+ AQLKGFPLF+H+NL LKD ++N SP+L + R E G LPG+ W+VF++
Sbjct: 171 KANENSLLSAQLKGFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQS 230
Query: 129 NSSTYEPIAWALRE------HDYETDGERMPL-ATVIQDHGRLDGVQRVLFGSGLQFWLH 181
N STYEP+ A H G L ATV+QD G DG+QRVLFG+ L FWLH
Sbjct: 231 NHSTYEPVLLAKTRSSESIPHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLH 290
Query: 182 RLLFLDALSYLSHGQLSLSLDRWILVDIDDIFVGEKGTRLHEEDVAALLTSQAALQRLVP 241
+L+F+DA+++L+ +LSL LDR+ILVDIDDIFVG++GTR+ EDV AL +Q L+ +P
Sbjct: 291 KLVFVDAVAFLTGKRLSLPLDRYILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRAHIP 350
Query: 242 GFRFNLGYSAKYYHHGTPTENLGDDALLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMM 301
F FNLGYS K++H GT E+ GDD LL + + F WF HMW+H QPHL++N S L +M
Sbjct: 351 NFTFNLGYSGKFFHTGTNAEDAGDDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMA 410
Query: 302 LNKQFALEHGIPTNSCYSVSPHHSGVYPVHEPLYEAWRKVWDVKVTSTEEYPHLRPARLR 361
LNK+FA+EHGIPT+ Y+V+PHHSGVYPVH LYEAW++VW ++VTSTEEYPHL+PAR R
Sbjct: 411 LNKKFAVEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKQVWSIRVTSTEEYPHLKPARYR 470
Query: 362 RGFRHRGVMVLPRQTCGLFTHTLLLERYPGGRHRLDRSIQGGELFQTVINNPINVFMTHM 421
RGF H G+MVLPRQTCGLFTHT+ YPGG LD+ I GGELF TV+ NPI++FMTH+
Sbjct: 471 RGFIHNGIMVLPRQTCGLFTHTIFYNEYPGGSSELDKIINGGELFLTVLLNPISIFMTHL 530
Query: 422 SNYGNDRLALYTFESVVKFLRCWTNVRLASAPPLALAEKYFQLRPDELNPLWGNPCDDIR 481
SNYGNDRL LYTF+ +V+FL WTN+RL + PP+ LA+KYFQ+ +E +PLW +PC+D R
Sbjct: 531 SNYGNDRLGLYTFKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKR 590
Query: 482 HRRIWSKSKWCGTLPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNN 541
H+ IWSK K C P+LL+IGPQKTG+TALY FL MHP L N PS T+EE+QFFN +N
Sbjct: 591 HKDIWSKEKTCDRFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHN 650
Query: 542 YLKGLDWYLNFFPPSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRA 601
Y KG+DWY+ FFP S FEKSA YFD ++ PRRA ALLP AK++ ILI+P+ RA
Sbjct: 651 YHKGIDWYMEFFPIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRA 710
Query: 602 YSWYQHIRSHGDPIANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSV 661
YSWYQH R+H DP+A YTFH +ITA A +LR L+NRCL PG Y+ ++ERWLS Y
Sbjct: 711 YSWYQHQRAHDDPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHA 770
Query: 662 HQLHVIDGSMLRSEPAVVMNTLQKFLKISPHIDYNKLL 699
+Q+ V+DG +LR+EPA VM+ +QKFL ++ IDY+K L
Sbjct: 771 NQILVLDGKLLRTEPAKVMDMVQKFLGVTNTIDYHKTL 808
Score = 75.4 bits (177), Expect = 8e-13
Identities = 33/60 (55%), Positives = 44/60 (73%)
Query: 762 ELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHNTALSKLLVRVGRPVPHWLKDEL 821
+L+ G KTKCLGKSKGR YP M+ S FL+ YY HN LSKLL ++G+ +P WL+++L
Sbjct: 819 QLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYYRDHNIELSKLLYKMGQTLPTWLREDL 878
>U18918-1|AAA75281.1| 882|Homo sapiens heparan
sulfate-N-deacetylase/N-sulfotransferase protein.
Length = 882
Score = 890 bits (2201), Expect = 0.0
Identities = 402/698 (57%), Positives = 518/698 (74%), Gaps = 9/698 (1%)
Query: 11 YKIEVA-GKS-LPVLTTLDKGRYGVIVFESLSKYANMDKWNRELLDKYCREYSVGVVGFA 68
Y+ E+A GK +P LT +GR+ +I++E++ KY N+D WNRELLDKYC Y VG++GF
Sbjct: 111 YRTEIAPGKGDMPTLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFF 170
Query: 69 TPSEETLVGAQLKGFPLFMHTNLRLKDATLNAASPVLRLARAGETAWGALPGDHWSVFRA 128
+E +L+ AQLKGFPLF+H+NL LKD ++N SP+L + R E G LPG+ W+VF++
Sbjct: 171 KANENSLLSAQLKGFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQS 230
Query: 129 NSSTYEPIAWALRE------HDYETDGERMPL-ATVIQDHGRLDGVQRVLFGSGLQFWLH 181
N STYEP+ A H G L ATV+QD G DG+QRVLFG+ L FWLH
Sbjct: 231 NHSTYEPVLLAKTRSSESIPHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLH 290
Query: 182 RLLFLDALSYLSHGQLSLSLDRWILVDIDDIFVGEKGTRLHEEDVAALLTSQAALQRLVP 241
+L+F+DA+++L+ +LSL LDR+ILVDIDDIFVG++GTR+ EDV AL +Q L+ +P
Sbjct: 291 KLVFVDAVAFLTGKRLSLPLDRYILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRAHIP 350
Query: 242 GFRFNLGYSAKYYHHGTPTENLGDDALLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMM 301
F FNLGYS K++H GT E+ GDD LL + + F WF HMW+H QPHL++N S L +M
Sbjct: 351 NFTFNLGYSGKFFHTGTNAEDAGDDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMA 410
Query: 302 LNKQFALEHGIPTNSCYSVSPHHSGVYPVHEPLYEAWRKVWDVKVTSTEEYPHLRPARLR 361
LNK+FA+EHGIPT+ Y+V+PHHSGVYPVH LYEAW++VW ++VTSTEEYPHL+PAR R
Sbjct: 411 LNKKFAVEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKQVWSIRVTSTEEYPHLKPARYR 470
Query: 362 RGFRHRGVMVLPRQTCGLFTHTLLLERYPGGRHRLDRSIQGGELFQTVINNPINVFMTHM 421
RGF H G+MVLPRQTCGLFTHT+ YPGG LD+ I GGELF TV+ NPI++FMTH+
Sbjct: 471 RGFIHNGIMVLPRQTCGLFTHTIFYNEYPGGSSELDKIINGGELFLTVLLNPISIFMTHL 530
Query: 422 SNYGNDRLALYTFESVVKFLRCWTNVRLASAPPLALAEKYFQLRPDELNPLWGNPCDDIR 481
SNYGNDRL LYTF+ +V+FL WTN+RL + PP+ LA+KYFQ+ +E +PLW +PC+D R
Sbjct: 531 SNYGNDRLGLYTFKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKR 590
Query: 482 HRRIWSKSKWCGTLPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNN 541
H+ IWSK K C P+LL+IGPQKTG+TALY FL MHP L N PS T+EE+QFFN +N
Sbjct: 591 HKDIWSKEKTCDRFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHN 650
Query: 542 YLKGLDWYLNFFPPSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRA 601
Y KG+DWY+ FFP S FEKSA YFD ++ PRRA ALLP AK++ ILI+P+ RA
Sbjct: 651 YHKGIDWYMEFFPIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRA 710
Query: 602 YSWYQHIRSHGDPIANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSV 661
YSWYQH R+H DP+A YTFH +ITA A +LR L+NRCL PG Y+ ++ERWLS Y
Sbjct: 711 YSWYQHQRAHDDPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHA 770
Query: 662 HQLHVIDGSMLRSEPAVVMNTLQKFLKISPHIDYNKLL 699
+Q+ V+DG +LR+EPA VM+ +QKFL ++ IDY+K L
Sbjct: 771 NQILVLDGKLLRTEPAKVMDMVQKFLGVTNTIDYHKTL 808
Score = 75.4 bits (177), Expect = 8e-13
Identities = 33/60 (55%), Positives = 44/60 (73%)
Query: 762 ELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHNTALSKLLVRVGRPVPHWLKDEL 821
+L+ G KTKCLGKSKGR YP M+ S FL+ YY HN LSKLL ++G+ +P WL+++L
Sbjct: 819 QLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYYRDHNIELSKLLYKMGQTLPTWLREDL 878
>U17970-1|AAA67765.1| 882|Homo sapiens heparan sulfate
N-deacetylase/N-sulfotransferase protein.
Length = 882
Score = 887 bits (2194), Expect = 0.0
Identities = 401/698 (57%), Positives = 517/698 (74%), Gaps = 9/698 (1%)
Query: 11 YKIEVA-GKS-LPVLTTLDKGRYGVIVFESLSKYANMDKWNRELLDKYCREYSVGVVGFA 68
Y+ E+A GK +P LT +GR+ +I++E++ KY N+D WNRELLDKYC Y VG++GF
Sbjct: 111 YRTEIAPGKGDMPTLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFF 170
Query: 69 TPSEETLVGAQLKGFPLFMHTNLRLKDATLNAASPVLRLARAGETAWGALPGDHWSVFRA 128
+E +L+ AQLKGFPLF+H+NL LKD ++N SP+L + R E G LPG+ W+VF++
Sbjct: 171 KANENSLLSAQLKGFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQS 230
Query: 129 NSSTYEPIAWALRE------HDYETDGERMPL-ATVIQDHGRLDGVQRVLFGSGLQFWLH 181
N STYEP+ A H G L ATV+QD G DG+QRVLFG+ L FWLH
Sbjct: 231 NHSTYEPVLLAKTRSSESIPHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLH 290
Query: 182 RLLFLDALSYLSHGQLSLSLDRWILVDIDDIFVGEKGTRLHEEDVAALLTSQAALQRLVP 241
+L+F+DA+++L+ +LSL LDR+ILVDIDDIFVG++GTR+ EDV AL +Q L+ +P
Sbjct: 291 KLVFVDAVAFLTGKRLSLPLDRYILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRAHIP 350
Query: 242 GFRFNLGYSAKYYHHGTPTENLGDDALLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMM 301
F FNLGYS K++H GT E+ GDD LL + + F WF HMW+H QPHL++N S L +M
Sbjct: 351 NFTFNLGYSGKFFHTGTNAEDAGDDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMA 410
Query: 302 LNKQFALEHGIPTNSCYSVSPHHSGVYPVHEPLYEAWRKVWDVKVTSTEEYPHLRPARLR 361
LNK+FA+EHGIPT+ Y+V+PHHSGVYPVH LYEAW++VW ++VTSTEEYPHL+PAR R
Sbjct: 411 LNKKFAVEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKQVWSIRVTSTEEYPHLKPARYR 470
Query: 362 RGFRHRGVMVLPRQTCGLFTHTLLLERYPGGRHRLDRSIQGGELFQTVINNPINVFMTHM 421
RGF H G+MVLPRQTCGLFTHT+ YPGG LD+ I GGELF TV+ NPI++FMTH+
Sbjct: 471 RGFIHNGIMVLPRQTCGLFTHTIFYNEYPGGSSELDKIINGGELFLTVLLNPISIFMTHL 530
Query: 422 SNYGNDRLALYTFESVVKFLRCWTNVRLASAPPLALAEKYFQLRPDELNPLWGNPCDDIR 481
SNYGNDRL LYTF+ +V+FL WTN+RL + PP+ LA+KYFQ+ +E +PLW +PC+D R
Sbjct: 531 SNYGNDRLGLYTFKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKR 590
Query: 482 HRRIWSKSKWCGTLPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNN 541
H+ IWSK K C P+LL+IGPQKTG+TALY FL MHP L N PS T+EE+QFFN +N
Sbjct: 591 HKDIWSKEKTCDRFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHN 650
Query: 542 YLKGLDWYLNFFPPSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRA 601
Y KG+DWY+ FFP S FEKSA YFD ++ PR A ALLP AK++ ILI+P+ RA
Sbjct: 651 YHKGIDWYMEFFPIPSNTTSDFYFEKSANYFDSEVAPRGAAALLPKAKVLTILINPADRA 710
Query: 602 YSWYQHIRSHGDPIANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSV 661
YSWYQH R+H DP+A YTFH +ITA A +LR L+NRCL PG Y+ ++ERWLS Y
Sbjct: 711 YSWYQHQRAHDDPVALKYTFHEVITAGSDASSRLRALQNRCLVPGWYATHIERWLSAYHA 770
Query: 662 HQLHVIDGSMLRSEPAVVMNTLQKFLKISPHIDYNKLL 699
+Q+ V+DG +LR+EPA VM+ +QKFL ++ IDY+K L
Sbjct: 771 NQILVLDGKLLRTEPAKVMDMVQKFLGVTNTIDYHKTL 808
Score = 75.4 bits (177), Expect = 8e-13
Identities = 33/60 (55%), Positives = 44/60 (73%)
Query: 762 ELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHNTALSKLLVRVGRPVPHWLKDEL 821
+L+ G KTKCLGKSKGR YP M+ S FL+ YY HN LSKLL ++G+ +P WL+++L
Sbjct: 819 QLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYYRDHNIELSKLLYKMGQTLPTWLREDL 878
>BC109310-1|AAI09311.1| 873|Homo sapiens
N-deacetylase/N-sulfotransferase (heparan glucosaminyl)
3 protein.
Length = 873
Score = 869 bits (2151), Expect = 0.0
Identities = 395/700 (56%), Positives = 516/700 (73%), Gaps = 5/700 (0%)
Query: 5 QSDIIWYKIEVA-GKS-LPVLTTLDKGRYGVIVFESLSKYANMDKWNRELLDKYCREYSV 62
+S Y IE+A GK LPVL KG+Y +I++E++ KY NMD WNR LLDKYC EY V
Sbjct: 100 ESSRFQYHIEIAPGKGDLPVLIDKMKGKYILIIYENILKYINMDSWNRSLLDKYCVEYGV 159
Query: 63 GVVGFATPSEETLVGAQLKGFPLFMHTNLRLKDATLNAASPVLRLARAGETAWGALPGDH 122
GV+GF SE+++ QLKGFP ++ NL +KD +N SP++R+ ++ + G+LPG
Sbjct: 160 GVIGFHKTSEKSVQSFQLKGFPFSIYGNLAVKDCCINPHSPLIRVTKSSKLEKGSLPGTD 219
Query: 123 WSVFRANSSTYEPIAWA---LREHDYETDGERMPLATVIQDHGRLDGVQRVLFGSGLQFW 179
W+VF+ N S Y+P+ +A E+ + + AT+I D G DG+QRVLFG+ L FW
Sbjct: 220 WTVFQINHSAYQPVIFAKVKTPENLSPSISKGAFYATIIHDLGLHDGIQRVLFGNNLNFW 279
Query: 180 LHRLLFLDALSYLSHGQLSLSLDRWILVDIDDIFVGEKGTRLHEEDVAALLTSQAALQRL 239
LH+L+F+DA+S+LS +L+LSLDR+ILVDIDDIFVG++GTR++ DV ALL +Q L+
Sbjct: 280 LHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNTNDVKALLDTQNLLRAQ 339
Query: 240 VPGFRFNLGYSAKYYHHGTPTENLGDDALLKHREYFNWFCHMWNHQQPHLYNNVSQLEAE 299
+ F FNLG+S K+YH GT E+ GDD LL + F WF HMW+H QPHL++N S L +
Sbjct: 340 ITNFTFNLGFSGKFYHTGTEEEDEGDDCLLGSVDEFWWFPHMWSHMQPHLFHNESSLVEQ 399
Query: 300 MMLNKQFALEHGIPTNSCYSVSPHHSGVYPVHEPLYEAWRKVWDVKVTSTEEYPHLRPAR 359
M+LNK+FALEHGIPT+ Y+V+PHHSGVYPVH LYEAW+KVW++K+TSTEEYPHL+PAR
Sbjct: 400 MILNKKFALEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKKVWNIKITSTEEYPHLKPAR 459
Query: 360 LRRGFRHRGVMVLPRQTCGLFTHTLLLERYPGGRHRLDRSIQGGELFQTVINNPINVFMT 419
RRGF H+ +MVLPRQTCGLFTHT+ + YPGG LD+SIQGGELF TV+ NPI++FMT
Sbjct: 460 YRRGFIHKNIMVLPRQTCGLFTHTIFYKEYPGGPKELDKSIQGGELFFTVVLNPISIFMT 519
Query: 420 HMSNYGNDRLALYTFESVVKFLRCWTNVRLASAPPLALAEKYFQLRPDELNPLWGNPCDD 479
H+SNYGNDRL LYTF ++ F++ WTN+RL + PP+ LA KYF+L PD+ +PLW NPCDD
Sbjct: 520 HLSNYGNDRLGLYTFVNLANFVKSWTNLRLQTLPPVQLAHKYFELFPDQKDPLWQNPCDD 579
Query: 480 IRHRRIWSKSKWCGTLPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNN 539
RHR IWSK K C LP+ LVIGPQKTG+TALY FL MHP++ N PSP T+EE+QFFN
Sbjct: 580 KRHRDIWSKEKTCDRLPKFLVIGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFNR 639
Query: 540 NNYLKGLDWYLNFFPPSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSK 599
NNY +G+DWY++FFP + FEKSA YF + P+RA +L+P AKII ILI PS
Sbjct: 640 NNYHRGIDWYMDFFPVPSNVTTDFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSD 699
Query: 600 RAYSWYQHIRSHGDPIANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEY 659
RAYSWYQH RSH DP A ++F+ +I+A AP +LR L+ RCL PG Y+ ++ERWL +
Sbjct: 700 RAYSWYQHQRSHEDPAALKFSFYEVISAGPRAPSELRALQKRCLVPGWYASHIERWLVYF 759
Query: 660 SVHQLHVIDGSMLRSEPAVVMNTLQKFLKISPHIDYNKLL 699
QL +IDG LR++PA VM+ +QKFL + PH +Y++ L
Sbjct: 760 PPFQLLIIDGQQLRTDPATVMDEVQKFLGVLPHYNYSEAL 799
Score = 79.4 bits (187), Expect = 5e-14
Identities = 35/60 (58%), Positives = 43/60 (71%)
Query: 762 ELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHNTALSKLLVRVGRPVPHWLKDEL 821
+L+ KTKCLGKSKGR YPPM+ S FL YY HN LSKLL ++G+P+P WL+ EL
Sbjct: 810 QLLEEGKTKCLGKSKGRKYPPMDSDSRTFLSSYYRDHNVELSKLLHKLGQPLPSWLRQEL 869
>BC109309-1|AAI09310.1| 873|Homo sapiens
N-deacetylase/N-sulfotransferase (heparan glucosaminyl)
3 protein.
Length = 873
Score = 869 bits (2151), Expect = 0.0
Identities = 395/700 (56%), Positives = 516/700 (73%), Gaps = 5/700 (0%)
Query: 5 QSDIIWYKIEVA-GKS-LPVLTTLDKGRYGVIVFESLSKYANMDKWNRELLDKYCREYSV 62
+S Y IE+A GK LPVL KG+Y +I++E++ KY NMD WNR LLDKYC EY V
Sbjct: 100 ESSRFQYHIEIAPGKGDLPVLIDKMKGKYILIIYENILKYINMDSWNRSLLDKYCVEYGV 159
Query: 63 GVVGFATPSEETLVGAQLKGFPLFMHTNLRLKDATLNAASPVLRLARAGETAWGALPGDH 122
GV+GF SE+++ QLKGFP ++ NL +KD +N SP++R+ ++ + G+LPG
Sbjct: 160 GVIGFHKTSEKSVQSFQLKGFPFSIYGNLAVKDCCINPHSPLIRVTKSSKLEKGSLPGTD 219
Query: 123 WSVFRANSSTYEPIAWA---LREHDYETDGERMPLATVIQDHGRLDGVQRVLFGSGLQFW 179
W+VF+ N S Y+P+ +A E+ + + AT+I D G DG+QRVLFG+ L FW
Sbjct: 220 WTVFQINHSAYQPVIFAKVKTPENLSPSISKGAFYATIIHDLGLHDGIQRVLFGNNLNFW 279
Query: 180 LHRLLFLDALSYLSHGQLSLSLDRWILVDIDDIFVGEKGTRLHEEDVAALLTSQAALQRL 239
LH+L+F+DA+S+LS +L+LSLDR+ILVDIDDIFVG++GTR++ DV ALL +Q L+
Sbjct: 280 LHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNTNDVKALLDTQNLLRAQ 339
Query: 240 VPGFRFNLGYSAKYYHHGTPTENLGDDALLKHREYFNWFCHMWNHQQPHLYNNVSQLEAE 299
+ F FNLG+S K+YH GT E+ GDD LL + F WF HMW+H QPHL++N S L +
Sbjct: 340 ITNFTFNLGFSGKFYHTGTEEEDEGDDCLLGSVDEFWWFPHMWSHMQPHLFHNESSLVEQ 399
Query: 300 MMLNKQFALEHGIPTNSCYSVSPHHSGVYPVHEPLYEAWRKVWDVKVTSTEEYPHLRPAR 359
M+LNK+FALEHGIPT+ Y+V+PHHSGVYPVH LYEAW+KVW++K+TSTEEYPHL+PAR
Sbjct: 400 MILNKKFALEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKKVWNIKITSTEEYPHLKPAR 459
Query: 360 LRRGFRHRGVMVLPRQTCGLFTHTLLLERYPGGRHRLDRSIQGGELFQTVINNPINVFMT 419
RRGF H+ +MVLPRQTCGLFTHT+ + YPGG LD+SIQGGELF TV+ NPI++FMT
Sbjct: 460 YRRGFIHKNIMVLPRQTCGLFTHTIFYKEYPGGPKELDKSIQGGELFFTVVLNPISIFMT 519
Query: 420 HMSNYGNDRLALYTFESVVKFLRCWTNVRLASAPPLALAEKYFQLRPDELNPLWGNPCDD 479
H+SNYGNDRL LYTF ++ F++ WTN+RL + PP+ LA KYF+L PD+ +PLW NPCDD
Sbjct: 520 HLSNYGNDRLGLYTFVNLANFVKSWTNLRLQTLPPVQLAHKYFELFPDQKDPLWQNPCDD 579
Query: 480 IRHRRIWSKSKWCGTLPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNN 539
RHR IWSK K C LP+ LVIGPQKTG+TALY FL MHP++ N PSP T+EE+QFFN
Sbjct: 580 KRHRDIWSKEKTCDRLPKFLVIGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFNR 639
Query: 540 NNYLKGLDWYLNFFPPSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSK 599
NNY +G+DWY++FFP + FEKSA YF + P+RA +L+P AKII ILI PS
Sbjct: 640 NNYHRGIDWYMDFFPVPSNVTTDFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSD 699
Query: 600 RAYSWYQHIRSHGDPIANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEY 659
RAYSWYQH RSH DP A ++F+ +I+A AP +LR L+ RCL PG Y+ ++ERWL +
Sbjct: 700 RAYSWYQHQRSHEDPAALKFSFYEVISAGPRAPSELRALQKRCLVPGWYASHIERWLVYF 759
Query: 660 SVHQLHVIDGSMLRSEPAVVMNTLQKFLKISPHIDYNKLL 699
QL +IDG LR++PA VM+ +QKFL + PH +Y++ L
Sbjct: 760 PPFQLLIIDGQQLRTDPATVMDEVQKFLGVLPHYNYSEAL 799
Score = 79.4 bits (187), Expect = 5e-14
Identities = 35/60 (58%), Positives = 43/60 (71%)
Query: 762 ELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHNTALSKLLVRVGRPVPHWLKDEL 821
+L+ KTKCLGKSKGR YPPM+ S FL YY HN LSKLL ++G+P+P WL+ EL
Sbjct: 810 QLLEEGKTKCLGKSKGRKYPPMDSDSRTFLSSYYRDHNVELSKLLHKLGQPLPSWLRQEL 869
>AF076605-1|AAD46061.1| 876|Homo sapiens heparan
N-deacetylase/N-sulfotransferase 3 protein.
Length = 876
Score = 869 bits (2151), Expect = 0.0
Identities = 395/700 (56%), Positives = 516/700 (73%), Gaps = 5/700 (0%)
Query: 5 QSDIIWYKIEVA-GKS-LPVLTTLDKGRYGVIVFESLSKYANMDKWNRELLDKYCREYSV 62
+S Y IE+A GK LPVL KG+Y +I++E++ KY NMD WNR LLDKYC EY V
Sbjct: 103 ESSRFQYHIEIAPGKGDLPVLIDKMKGKYILIIYENILKYINMDSWNRSLLDKYCVEYGV 162
Query: 63 GVVGFATPSEETLVGAQLKGFPLFMHTNLRLKDATLNAASPVLRLARAGETAWGALPGDH 122
GV+GF SE+++ QLKGFP ++ NL +KD +N SP++R+ ++ + G+LPG
Sbjct: 163 GVIGFHKTSEKSVQSFQLKGFPFSIYGNLAVKDCCINPHSPLIRVTKSSKLEKGSLPGTD 222
Query: 123 WSVFRANSSTYEPIAWA---LREHDYETDGERMPLATVIQDHGRLDGVQRVLFGSGLQFW 179
W+VF+ N S Y+P+ +A E+ + + AT+I D G DG+QRVLFG+ L FW
Sbjct: 223 WTVFQINHSAYQPVIFAKVKTPENLSPSISKGAFYATIIHDLGLHDGIQRVLFGNNLNFW 282
Query: 180 LHRLLFLDALSYLSHGQLSLSLDRWILVDIDDIFVGEKGTRLHEEDVAALLTSQAALQRL 239
LH+L+F+DA+S+LS +L+LSLDR+ILVDIDDIFVG++GTR++ DV ALL +Q L+
Sbjct: 283 LHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNTNDVKALLDTQNLLRAQ 342
Query: 240 VPGFRFNLGYSAKYYHHGTPTENLGDDALLKHREYFNWFCHMWNHQQPHLYNNVSQLEAE 299
+ F FNLG+S K+YH GT E+ GDD LL + F WF HMW+H QPHL++N S L +
Sbjct: 343 ITNFTFNLGFSGKFYHTGTEEEDEGDDCLLGSVDEFWWFPHMWSHMQPHLFHNESSLVEQ 402
Query: 300 MMLNKQFALEHGIPTNSCYSVSPHHSGVYPVHEPLYEAWRKVWDVKVTSTEEYPHLRPAR 359
M+LNK+FALEHGIPT+ Y+V+PHHSGVYPVH LYEAW+KVW++K+TSTEEYPHL+PAR
Sbjct: 403 MILNKKFALEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKKVWNIKITSTEEYPHLKPAR 462
Query: 360 LRRGFRHRGVMVLPRQTCGLFTHTLLLERYPGGRHRLDRSIQGGELFQTVINNPINVFMT 419
RRGF H+ +MVLPRQTCGLFTHT+ + YPGG LD+SIQGGELF TV+ NPI++FMT
Sbjct: 463 YRRGFIHKNIMVLPRQTCGLFTHTIFYKEYPGGPKELDKSIQGGELFFTVVLNPISIFMT 522
Query: 420 HMSNYGNDRLALYTFESVVKFLRCWTNVRLASAPPLALAEKYFQLRPDELNPLWGNPCDD 479
H+SNYGNDRL LYTF ++ F++ WTN+RL + PP+ LA KYF+L PD+ +PLW NPCDD
Sbjct: 523 HLSNYGNDRLGLYTFVNLANFVKSWTNLRLQTLPPVQLAHKYFELFPDQKDPLWQNPCDD 582
Query: 480 IRHRRIWSKSKWCGTLPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNN 539
RHR IWSK K C LP+ LVIGPQKTG+TALY FL MHP++ N PSP T+EE+QFFN
Sbjct: 583 KRHRDIWSKEKTCDRLPKFLVIGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFNR 642
Query: 540 NNYLKGLDWYLNFFPPSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSK 599
NNY +G+DWY++FFP + FEKSA YF + P+RA +L+P AKII ILI PS
Sbjct: 643 NNYHRGIDWYMDFFPVPSNVTTDFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSD 702
Query: 600 RAYSWYQHIRSHGDPIANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEY 659
RAYSWYQH RSH DP A ++F+ +I+A AP +LR L+ RCL PG Y+ ++ERWL +
Sbjct: 703 RAYSWYQHQRSHEDPAALKFSFYEVISAGPRAPSELRALQKRCLVPGWYASHIERWLVYF 762
Query: 660 SVHQLHVIDGSMLRSEPAVVMNTLQKFLKISPHIDYNKLL 699
QL +IDG LR++PA VM+ +QKFL + PH +Y++ L
Sbjct: 763 PPFQLLIIDGQQLRTDPATVMDEVQKFLGVLPHYNYSEAL 802
Score = 79.4 bits (187), Expect = 5e-14
Identities = 35/60 (58%), Positives = 43/60 (71%)
Query: 762 ELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHNTALSKLLVRVGRPVPHWLKDEL 821
+L+ KTKCLGKSKGR YPPM+ S FL YY HN LSKLL ++G+P+P WL+ EL
Sbjct: 813 QLLEEGKTKCLGKSKGRKYPPMDSDSRTFLSSYYRDHNVELSKLLHKLGQPLPSWLRQEL 872
>AF074924-1|AAD15978.1| 873|Homo sapiens heparan sulfate
N-deacetylase/N-sulfotransferase 3 protein.
Length = 873
Score = 869 bits (2151), Expect = 0.0
Identities = 395/700 (56%), Positives = 516/700 (73%), Gaps = 5/700 (0%)
Query: 5 QSDIIWYKIEVA-GKS-LPVLTTLDKGRYGVIVFESLSKYANMDKWNRELLDKYCREYSV 62
+S Y IE+A GK LPVL KG+Y +I++E++ KY NMD WNR LLDKYC EY V
Sbjct: 100 ESSRFQYHIEIAPGKGDLPVLIDKMKGKYILIIYENILKYINMDSWNRSLLDKYCVEYGV 159
Query: 63 GVVGFATPSEETLVGAQLKGFPLFMHTNLRLKDATLNAASPVLRLARAGETAWGALPGDH 122
GV+GF SE+++ QLKGFP ++ NL +KD +N SP++R+ ++ + G+LPG
Sbjct: 160 GVIGFHKTSEKSVQSFQLKGFPFSIYGNLAVKDCCINPHSPLIRVTKSSKLEKGSLPGTD 219
Query: 123 WSVFRANSSTYEPIAWA---LREHDYETDGERMPLATVIQDHGRLDGVQRVLFGSGLQFW 179
W+VF+ N S Y+P+ +A E+ + + AT+I D G DG+QRVLFG+ L FW
Sbjct: 220 WTVFQINHSAYQPVIFAKVKTPENLSPSISKGAFYATIIHDLGLHDGIQRVLFGNNLNFW 279
Query: 180 LHRLLFLDALSYLSHGQLSLSLDRWILVDIDDIFVGEKGTRLHEEDVAALLTSQAALQRL 239
LH+L+F+DA+S+LS +L+LSLDR+ILVDIDDIFVG++GTR++ DV ALL +Q L+
Sbjct: 280 LHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNTNDVKALLDTQNLLRAQ 339
Query: 240 VPGFRFNLGYSAKYYHHGTPTENLGDDALLKHREYFNWFCHMWNHQQPHLYNNVSQLEAE 299
+ F FNLG+S K+YH GT E+ GDD LL + F WF HMW+H QPHL++N S L +
Sbjct: 340 ITNFTFNLGFSGKFYHTGTEEEDEGDDCLLGSVDEFWWFPHMWSHMQPHLFHNESSLVEQ 399
Query: 300 MMLNKQFALEHGIPTNSCYSVSPHHSGVYPVHEPLYEAWRKVWDVKVTSTEEYPHLRPAR 359
M+LNK+FALEHGIPT+ Y+V+PHHSGVYPVH LYEAW+KVW++K+TSTEEYPHL+PAR
Sbjct: 400 MILNKKFALEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKKVWNIKITSTEEYPHLKPAR 459
Query: 360 LRRGFRHRGVMVLPRQTCGLFTHTLLLERYPGGRHRLDRSIQGGELFQTVINNPINVFMT 419
RRGF H+ +MVLPRQTCGLFTHT+ + YPGG LD+SIQGGELF TV+ NPI++FMT
Sbjct: 460 YRRGFIHKNIMVLPRQTCGLFTHTIFYKEYPGGPKELDKSIQGGELFFTVVLNPISIFMT 519
Query: 420 HMSNYGNDRLALYTFESVVKFLRCWTNVRLASAPPLALAEKYFQLRPDELNPLWGNPCDD 479
H+SNYGNDRL LYTF ++ F++ WTN+RL + PP+ LA KYF+L PD+ +PLW NPCDD
Sbjct: 520 HLSNYGNDRLGLYTFVNLANFVKSWTNLRLQTLPPVQLAHKYFELFPDQKDPLWQNPCDD 579
Query: 480 IRHRRIWSKSKWCGTLPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNN 539
RHR IWSK K C LP+ LVIGPQKTG+TALY FL MHP++ N PSP T+EE+QFFN
Sbjct: 580 KRHRDIWSKEKTCDRLPKFLVIGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFNR 639
Query: 540 NNYLKGLDWYLNFFPPSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSK 599
NNY +G+DWY++FFP + FEKSA YF + P+RA +L+P AKII ILI PS
Sbjct: 640 NNYHRGIDWYMDFFPVPSNVTTDFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSD 699
Query: 600 RAYSWYQHIRSHGDPIANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEY 659
RAYSWYQH RSH DP A ++F+ +I+A AP +LR L+ RCL PG Y+ ++ERWL +
Sbjct: 700 RAYSWYQHQRSHEDPAALKFSFYEVISAGPRAPSELRALQKRCLVPGWYASHIERWLVYF 759
Query: 660 SVHQLHVIDGSMLRSEPAVVMNTLQKFLKISPHIDYNKLL 699
QL +IDG LR++PA VM+ +QKFL + PH +Y++ L
Sbjct: 760 PPFQLLIIDGQQLRTDPATVMDEVQKFLGVLPHYNYSEAL 799
Score = 79.4 bits (187), Expect = 5e-14
Identities = 35/60 (58%), Positives = 43/60 (71%)
Query: 762 ELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHNTALSKLLVRVGRPVPHWLKDEL 821
+L+ KTKCLGKSKGR YPPM+ S FL YY HN LSKLL ++G+P+P WL+ EL
Sbjct: 810 QLLEEGKTKCLGKSKGRKYPPMDSDSRTFLSSYYRDHNVELSKLLHKLGQPLPSWLRQEL 869
>AB036429-1|BAB18535.1| 872|Homo sapiens
N-deacetylase/N-sulfotransferase 4 protein.
Length = 872
Score = 861 bits (2131), Expect = 0.0
Identities = 385/693 (55%), Positives = 509/693 (73%), Gaps = 3/693 (0%)
Query: 10 WYKIEVAGKS-LPVLTTLDKGRYGVIVFESLSKYANMDKWNRELLDKYCREYSVGVVGFA 68
++ + GK +P LT KG+Y ++++E++ KY +MD WNRELL+KYC EYSV ++GF
Sbjct: 106 YHMVIAPGKGDIPPLTDNGKGKYTLVIYENILKYVSMDSWNRELLEKYCVEYSVSIIGFH 165
Query: 69 TPSEETLVGAQLKGFPLFMHTNLRLKDATLNAASPVLRLARAGETAWGALPGDHWSVFRA 128
+E +L QLKGFPL + NL LKD +N SP+L + +A + G LPG+ W++F+
Sbjct: 166 KANENSLPSTQLKGFPLNLFNNLALKDCFVNPQSPLLHITKAPKVEKGPLPGEDWTIFQY 225
Query: 129 NSSTYEPIAWA--LREHDYETDGERMPLATVIQDHGRLDGVQRVLFGSGLQFWLHRLLFL 186
N STY+P+ E + + ATVIQD G DG+QRVLFG+ L FWLH+L+F+
Sbjct: 226 NHSTYQPVLLTELQTEKSLSSLSSKTLFATVIQDLGLHDGIQRVLFGNNLNFWLHKLIFI 285
Query: 187 DALSYLSHGQLSLSLDRWILVDIDDIFVGEKGTRLHEEDVAALLTSQAALQRLVPGFRFN 246
DA+S+LS +L+LSLDR+ILVDIDDIFVG++GTR++ +DV ALL +Q L+ V F FN
Sbjct: 286 DAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNVKDVKALLETQNLLRTQVANFTFN 345
Query: 247 LGYSAKYYHHGTPTENLGDDALLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMMLNKQF 306
LG+S K+YH GT E+ GDD LL+ + F WF HMW+H QPHL++N S L +M+LNK+F
Sbjct: 346 LGFSGKFYHTGTEEEDEGDDLLLRSVDEFWWFPHMWSHMQPHLFHNESSLVEQMILNKEF 405
Query: 307 ALEHGIPTNSCYSVSPHHSGVYPVHEPLYEAWRKVWDVKVTSTEEYPHLRPARLRRGFRH 366
ALEHGIP N Y+V+PHHSGVYPVH LY AW+KVW ++VTSTEEYPHL+PAR R+GF H
Sbjct: 406 ALEHGIPINMGYAVAPHHSGVYPVHIQLYAAWKKVWGIQVTSTEEYPHLKPARYRKGFIH 465
Query: 367 RGVMVLPRQTCGLFTHTLLLERYPGGRHRLDRSIQGGELFQTVINNPINVFMTHMSNYGN 426
+MVLPRQTCGLFTHT+ + YPGG LD+SI+GGELF T++ NPI++FMTH+SNYGN
Sbjct: 466 NSIMVLPRQTCGLFTHTIFYKEYPGGPQELDKSIRGGELFLTILLNPISIFMTHLSNYGN 525
Query: 427 DRLALYTFESVVKFLRCWTNVRLASAPPLALAEKYFQLRPDELNPLWGNPCDDIRHRRIW 486
DRL LYTF ++V F++ WTN++L + PP+ LA +YF+L P++ +PLW NPCDD RH+ IW
Sbjct: 526 DRLGLYTFVNLVNFVQSWTNLKLQTLPPVQLAHQYFELFPEQKDPLWQNPCDDKRHKDIW 585
Query: 487 SKSKWCGTLPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGL 546
S+ K C LP+ LVIGPQKTG+TALY FL MHP++ NLPSP T+EE+QFFN NNY KG+
Sbjct: 586 SREKTCDHLPKFLVIGPQKTGTTALYLFLLMHPSIISNLPSPKTFEEVQFFNGNNYHKGI 645
Query: 547 DWYLNFFPPSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQ 606
DWY++FFP S FEKSA YF + PRRA +L+P AKII ILI PS RAYSWYQ
Sbjct: 646 DWYMDFFPTPSNTTSDFLFEKSANYFHSEEAPRRAASLVPKAKIITILIDPSDRAYSWYQ 705
Query: 607 HIRSHGDPIANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHV 666
H RSH DP A + F+ +I+ AP L+ L+ RCL PG Y+ ++ERWL+ ++ QL +
Sbjct: 706 HQRSHEDPAALRFNFYEVISTGHWAPSDLKTLQRRCLVPGWYAVHIERWLTYFATSQLLI 765
Query: 667 IDGSMLRSEPAVVMNTLQKFLKISPHIDYNKLL 699
IDG LRS+PA VM+ +QKFL ++P +Y++ L
Sbjct: 766 IDGQQLRSDPATVMDEVQKFLGVTPRYNYSEAL 798
Score = 84.6 bits (200), Expect = 1e-15
Identities = 37/60 (61%), Positives = 44/60 (73%)
Query: 762 ELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHNTALSKLLVRVGRPVPHWLKDEL 821
+L+ G KTKCLGKSKGR YPPM+ S FL YY HN LSKLL R+G+P+P WL+ EL
Sbjct: 809 QLLEGGKTKCLGKSKGRKYPPMDPESRTFLSNYYRDHNVELSKLLHRLGQPLPSWLRQEL 868
>AB209107-1|BAD92344.1| 698|Homo sapiens
N-deacetylase/N-sulfotransferase (heparan glucosaminyl)
1 variant protein.
Length = 698
Score = 792 bits (1958), Expect = 0.0
Identities = 358/615 (58%), Positives = 456/615 (74%), Gaps = 7/615 (1%)
Query: 92 RLKDATLNAASPVLRLARAGETAWGALPGDHWSVFRANSSTYEPIAWALRE------HDY 145
RLKD ++N SP+L + R E G LPG+ W+VF++N STYEP+ A H
Sbjct: 10 RLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQSNHSTYEPVLLAKTRSSESIPHLG 69
Query: 146 ETDGERMPL-ATVIQDHGRLDGVQRVLFGSGLQFWLHRLLFLDALSYLSHGQLSLSLDRW 204
G L ATV+QD G DG+QRVLFG+ L FWLH+L+F+DA+++L+ +LSL LDR+
Sbjct: 70 ADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAFLTGKRLSLPLDRY 129
Query: 205 ILVDIDDIFVGEKGTRLHEEDVAALLTSQAALQRLVPGFRFNLGYSAKYYHHGTPTENLG 264
ILVDIDDIFVG++GTR+ EDV AL +Q L+ +P F FNLGYS K++H GT E+ G
Sbjct: 130 ILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRAHIPNFTFNLGYSGKFFHTGTNAEDAG 189
Query: 265 DDALLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMMLNKQFALEHGIPTNSCYSVSPHH 324
DD LL + + F WF HMW+H QPHL++N S L +M LNK+FA+EHGIPT+ Y+V+PHH
Sbjct: 190 DDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHGIPTDMGYAVAPHH 249
Query: 325 SGVYPVHEPLYEAWRKVWDVKVTSTEEYPHLRPARLRRGFRHRGVMVLPRQTCGLFTHTL 384
SGVYPVH LYEAW++VW ++VTSTEEYPHL+PAR RRGF H G+MVLPRQTCGLFTHT+
Sbjct: 250 SGVYPVHVQLYEAWKQVWSIRVTSTEEYPHLKPARYRRGFIHNGIMVLPRQTCGLFTHTI 309
Query: 385 LLERYPGGRHRLDRSIQGGELFQTVINNPINVFMTHMSNYGNDRLALYTFESVVKFLRCW 444
YPGG LD+ I GGELF TV+ NPI++FMTH+SNYGNDRL LYTF+ +V+FL W
Sbjct: 310 FYNEYPGGSSELDKIINGGELFLTVLLNPISIFMTHLSNYGNDRLGLYTFKHLVRFLHSW 369
Query: 445 TNVRLASAPPLALAEKYFQLRPDELNPLWGNPCDDIRHRRIWSKSKWCGTLPRLLVIGPQ 504
TN+RL + PP+ LA+KYFQ+ +E +PLW +PC+D RH+ IWSK K C P+LL+IGPQ
Sbjct: 370 TNLRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTCDRFPKLLIIGPQ 429
Query: 505 KTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFPPSLTNNSQIT 564
KTG+TALY FL MHP L N PS T+EE+QFFN +NY KG+DWY+ FFP S
Sbjct: 430 KTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFFPIPSNTTSDFY 489
Query: 565 FEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDPIANNYTFHTI 624
FEKSA YFD ++ PRRA ALLP AK++ ILI+P+ RAYSWYQH R+H DP+A YTFH +
Sbjct: 490 FEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQHQRAHDDPVALKYTFHEV 549
Query: 625 ITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRSEPAVVMNTLQ 684
ITA A +LR L+NRCL PG Y+ ++ERWLS Y +Q+ V+DG +LR+EPA VM+ +Q
Sbjct: 550 ITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKLLRTEPAKVMDMVQ 609
Query: 685 KFLKISPHIDYNKLL 699
KFL ++ IDY+K L
Sbjct: 610 KFLGVTNTIDYHKTL 624
Score = 75.4 bits (177), Expect = 8e-13
Identities = 33/60 (55%), Positives = 44/60 (73%)
Query: 762 ELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHNTALSKLLVRVGRPVPHWLKDEL 821
+L+ G KTKCLGKSKGR YP M+ S FL+ YY HN LSKLL ++G+ +P WL+++L
Sbjct: 635 QLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYYRDHNIELSKLLYKMGQTLPTWLREDL 694
>BC012888-1|AAH12888.1| 556|Homo sapiens NDST1 protein protein.
Length = 556
Score = 505 bits (1246), Expect = e-142
Identities = 233/414 (56%), Positives = 303/414 (73%), Gaps = 9/414 (2%)
Query: 11 YKIEVA-GKS-LPVLTTLDKGRYGVIVFESLSKYANMDKWNRELLDKYCREYSVGVVGFA 68
Y+ E+A GK +P LT +GR+ +I++E++ KY N+D WNRELLDKYC Y VG++GF
Sbjct: 111 YRTEIAPGKGDMPTLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFF 170
Query: 69 TPSEETLVGAQLKGFPLFMHTNLRLKDATLNAASPVLRLARAGETAWGALPGDHWSVFRA 128
+E +L+ AQLKGFPLF+H+NL LKD ++N SP+L + R E G LPG+ W+VF++
Sbjct: 171 KANENSLLSAQLKGFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQS 230
Query: 129 NSSTYEPIAWALRE------HDYETDGERMPL-ATVIQDHGRLDGVQRVLFGSGLQFWLH 181
N STYEP+ A H G L ATV+QD G DG+QRVLFG+ L FWLH
Sbjct: 231 NHSTYEPVLLAKTRSSESIPHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLH 290
Query: 182 RLLFLDALSYLSHGQLSLSLDRWILVDIDDIFVGEKGTRLHEEDVAALLTSQAALQRLVP 241
+L+F+DA+++L+ +LSL LDR+ILVDIDDIFVG++GTR+ EDV AL +Q L+ +P
Sbjct: 291 KLVFVDAVAFLTGKRLSLPLDRYILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRAHIP 350
Query: 242 GFRFNLGYSAKYYHHGTPTENLGDDALLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMM 301
F FNLGYS K++ GT E+ GDD LL + + F WF HMW+H QPHL++N S L +M
Sbjct: 351 NFTFNLGYSGKFFQTGTNAEDAGDDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMA 410
Query: 302 LNKQFALEHGIPTNSCYSVSPHHSGVYPVHEPLYEAWRKVWDVKVTSTEEYPHLRPARLR 361
LNK+FA+EHGIPT+ Y+V+PHHSGVYPVH LYEAW++VW ++VTSTEEYPHL+PAR R
Sbjct: 411 LNKKFAVEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKQVWSIRVTSTEEYPHLKPARYR 470
Query: 362 RGFRHRGVMVLPRQTCGLFTHTLLLERYPGGRHRLDRSIQGGELFQTVINNPIN 415
RGF H G+MVLPRQTCGLFTHT+ YPGG LD+ I GGELF TV+ NP++
Sbjct: 471 RGFIHNGIMVLPRQTCGLFTHTIFYNEYPGGSSELDKIINGGELFLTVLLNPVS 524
>BC113075-1|AAI13076.1| 369|Homo sapiens NDST4 protein protein.
Length = 369
Score = 488 bits (1204), Expect = e-137
Identities = 208/326 (63%), Positives = 258/326 (79%)
Query: 281 MWNHQQPHLYNNVSQLEAEMMLNKQFALEHGIPTNSCYSVSPHHSGVYPVHEPLYEAWRK 340
MW+H QPHL++N S L +M+LNK+FALEHGIP N Y+V+PHHSGVYPVH LY AW+K
Sbjct: 1 MWSHMQPHLFHNESSLVEQMILNKEFALEHGIPINMGYAVAPHHSGVYPVHIQLYAAWKK 60
Query: 341 VWDVKVTSTEEYPHLRPARLRRGFRHRGVMVLPRQTCGLFTHTLLLERYPGGRHRLDRSI 400
VW ++VTSTEEYPHL+PAR R+GF H +MVLPRQTCGLFTHT+ + YPGG LD+SI
Sbjct: 61 VWGIQVTSTEEYPHLKPARYRKGFIHNSIMVLPRQTCGLFTHTIFYKEYPGGPQELDKSI 120
Query: 401 QGGELFQTVINNPINVFMTHMSNYGNDRLALYTFESVVKFLRCWTNVRLASAPPLALAEK 460
+GGELF T++ NPI++FMTH+SNYGNDRL LYTF ++V F++ WTN++L + PP+ LA +
Sbjct: 121 RGGELFLTILLNPISIFMTHLSNYGNDRLGLYTFVNLVNFVQSWTNLKLQTLPPVQLAHQ 180
Query: 461 YFQLRPDELNPLWGNPCDDIRHRRIWSKSKWCGTLPRLLVIGPQKTGSTALYTFLAMHPT 520
YF+L P++ +PLW NPCDD RH+ IWS+ K C LP+ LVIGPQKTG+TALY FL MHP+
Sbjct: 181 YFELFPEQKDPLWQNPCDDKRHKDIWSREKTCDHLPKFLVIGPQKTGTTALYLFLLMHPS 240
Query: 521 LKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFPPSLTNNSQITFEKSATYFDGDLVPRR 580
+ NLPSP T+EE+QFFN NNY KG+DWY++FFP S FEKSA YF + PRR
Sbjct: 241 IISNLPSPKTFEEVQFFNGNNYHKGIDWYMDFFPTPSNTTSDFLFEKSANYFHSEEAPRR 300
Query: 581 AHALLPNAKIIAILISPSKRAYSWYQ 606
A +L+P AKII ILI PS RAYSWYQ
Sbjct: 301 AASLVPKAKIITILIDPSDRAYSWYQ 326
>AB208870-1|BAD92107.1| 364|Homo sapiens
N-deacetylase/N-sulfotransferase (heparan glucosaminyl)
2 variant protein.
Length = 364
Score = 279 bits (684), Expect = 3e-74
Identities = 135/253 (53%), Positives = 180/253 (71%), Gaps = 6/253 (2%)
Query: 11 YKIEVA-GKS-LPVLTTLDKGRYGVIVFESLSKYANMDKWNRELLDKYCREYSVGVVGFA 68
Y E+A G+ +P LT GRY ++++E+L KY N+D W+RELLD+YC EY VG++GF
Sbjct: 100 YSTELAPGRGDMPTLTDNTHGRYVLVIYENLLKYVNLDAWSRELLDRYCVEYGVGIIGFF 159
Query: 69 TPSEETLVGAQLKGFPLFMHTNLRLKDATLNAASPVLRLARAGETAWGALPGDHWSVFRA 128
E +L+ AQLKGFPLF+H+NL L+D +N ++P+L L R G LPGD W++F++
Sbjct: 160 RAHEHSLLSAQLKGFPLFLHSNLGLRDYQVNPSAPLLHLTRPSRLEPGPLPGDDWTIFQS 219
Query: 129 NSSTYEPIAWA-LREHDYETDG---ERMPLATVIQDHGRLDGVQRVLFGSGLQFWLHRLL 184
N STYEP+ A LR + G R L TV+QD G DG+QRVLFG GL FWLH+L+
Sbjct: 220 NHSTYEPVLLASLRPAEPAVPGPVLRRARLPTVVQDLGLHDGIQRVLFGHGLSFWLHKLI 279
Query: 185 FLDALSYLSHGQLSLSLDRWILVDIDDIFVGEKGTRLHEEDVAALLTSQAALQRLVPGFR 244
F+DA++YL+ +L L LDR+ILVDIDDIFVG++GTR+ DV ALLT+Q L+ LVP F
Sbjct: 280 FVDAVAYLTGKRLCLDLDRYILVDIDDIFVGKEGTRMKVADVEALLTTQNKLRTLVPNFT 339
Query: 245 FNLGYSAKYYHHG 257
FNLG+S K+YH G
Sbjct: 340 FNLGFSGKFYHTG 352
>AC108201-1|AAY41001.1| 356|Homo sapiens unknown protein.
Length = 356
Score = 259 bits (635), Expect = 2e-68
Identities = 127/256 (49%), Positives = 178/256 (69%), Gaps = 5/256 (1%)
Query: 5 QSDIIWYKIEVA-GKS-LPVLTTLDKGRYGVIVFESLSKYANMDKWNRELLDKYCREYSV 62
+S Y IE+A GK LPVL KG+Y +I++E++ KY NMD WNR LLDKYC EY V
Sbjct: 100 ESSRFQYHIEIAPGKGDLPVLIDKMKGKYILIIYENILKYINMDSWNRSLLDKYCVEYGV 159
Query: 63 GVVGFATPSEETLVGAQLKGFPLFMHTNLRLKDATLNAASPVLRLARAGETAWGALPGDH 122
GV+GF SE+++ QLKGFP ++ NL +KD +N SP++R+ ++ + G+LPG
Sbjct: 160 GVIGFHKTSEKSVQSFQLKGFPFSIYGNLAVKDCCINPHSPLIRVTKSSKLEKGSLPGTD 219
Query: 123 WSVFRANSSTYEPIAWA---LREHDYETDGERMPLATVIQDHGRLDGVQRVLFGSGLQFW 179
W+VF+ N S Y+P+ +A E+ + + AT+I D G DG+QRVLFG+ L FW
Sbjct: 220 WTVFQINHSAYQPVIFAKVKTPENLSPSISKGAFYATIIHDLGLHDGIQRVLFGNNLNFW 279
Query: 180 LHRLLFLDALSYLSHGQLSLSLDRWILVDIDDIFVGEKGTRLHEEDVAALLTSQAALQRL 239
LH+L+F+DA+S+LS +L+LSLDR+ILVDIDDIFVG++GTR++ DV ALL +Q L+
Sbjct: 280 LHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNTNDVKALLDTQNLLRAQ 339
Query: 240 VPGFRFNLGYSAKYYH 255
+ F FNLG+S K+YH
Sbjct: 340 ITNFTFNLGFSGKFYH 355
>AC110999-1|AAY41056.1| 156|Homo sapiens unknown protein.
Length = 156
Score = 242 bits (593), Expect = 3e-63
Identities = 104/156 (66%), Positives = 126/156 (80%)
Query: 258 TPTENLGDDALLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMMLNKQFALEHGIPTNSC 317
T E+ GDD LL + F WF HMW+H QPHL++N S L +M+LNK+FALEHGIPT+
Sbjct: 1 TEEEDEGDDCLLGSVDEFWWFPHMWSHMQPHLFHNESSLVEQMILNKKFALEHGIPTDMG 60
Query: 318 YSVSPHHSGVYPVHEPLYEAWRKVWDVKVTSTEEYPHLRPARLRRGFRHRGVMVLPRQTC 377
Y+V+PHHSGVYPVH LYEAW+KVW++K+TSTEEYPHL+PAR RRGF H+ +MVLPRQTC
Sbjct: 61 YAVAPHHSGVYPVHVQLYEAWKKVWNIKITSTEEYPHLKPARYRRGFIHKNIMVLPRQTC 120
Query: 378 GLFTHTLLLERYPGGRHRLDRSIQGGELFQTVINNP 413
GLFTHT+ + YPGG LD+SIQGGELF TV+ NP
Sbjct: 121 GLFTHTIFYKEYPGGPKELDKSIQGGELFFTVVLNP 156
>AY358852-1|AAQ89211.1| 385|Homo sapiens HSS3 protein.
Length = 385
Score = 230 bits (562), Expect = 2e-59
Identities = 114/231 (49%), Positives = 160/231 (69%), Gaps = 5/231 (2%)
Query: 5 QSDIIWYKIEVA-GKS-LPVLTTLDKGRYGVIVFESLSKYANMDKWNRELLDKYCREYSV 62
+S Y IE+A GK LPVL KG+Y +I++E++ KY NMD WNR LLDKYC EY V
Sbjct: 100 ESSRFQYHIEIAPGKGDLPVLIDKMKGKYILIIYENILKYINMDSWNRSLLDKYCVEYGV 159
Query: 63 GVVGFATPSEETLVGAQLKGFPLFMHTNLRLKDATLNAASPVLRLARAGETAWGALPGDH 122
GV+GF SE+++ QLKGFP ++ NL +KD +N SP++R+ ++ + G+LPG
Sbjct: 160 GVIGFHKTSEKSVQSFQLKGFPFSIYGNLAVKDCCINPHSPLIRVTKSSKLEKGSLPGTD 219
Query: 123 WSVFRANSSTYEPIAWA---LREHDYETDGERMPLATVIQDHGRLDGVQRVLFGSGLQFW 179
W+VF+ N S Y+P+ +A E+ + + AT+I D G DG+QRVLFG+ L FW
Sbjct: 220 WTVFQINHSAYQPVIFAKVKTPENLSPSISKGAFYATIIHDLGLHDGIQRVLFGNNLNFW 279
Query: 180 LHRLLFLDALSYLSHGQLSLSLDRWILVDIDDIFVGEKGTRLHEEDVAALL 230
LH+L+F+DA+S+LS +L+LSLDR+ILVDIDDIFVG++GTR++ DV L
Sbjct: 280 LHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNTNDVKVRL 330
>BC093913-1|AAH93913.1| 346|Homo sapiens heparan sulfate
(glucosamine) 3-O-sulfotransferase 5 protein.
Length = 346
Score = 105 bits (252), Expect = 6e-22
Identities = 66/204 (32%), Positives = 105/204 (51%), Gaps = 12/204 (5%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNN-NYLKGLDWYLNFF 553
LP+ ++IG +K G+ AL L +HP + +E+ FF+N+ NY KG++WY
Sbjct: 90 LPKAIIIGVRKGGTRALLEMLNLHPAVV------KASQEIHFFDNDENYGKGIEWYRKKM 143
Query: 554 PPSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGD 613
P S QIT EKS YF + VP R + + + K++ I+ P+ RA S Y + G
Sbjct: 144 PFSYPQ--QITIEKSPAYFITEEVPERIYKMNSSIKLLIIVREPTTRAISDYTQVLE-GK 200
Query: 614 PIANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLR 673
N + A D ++ + + + + Y+ +LERWL + + Q HV+DG L
Sbjct: 201 ERKNKTYYKFEKLAIDPNTCEV-NTKYKAVRTSIYTKHLERWLKYFPIEQFHVVDGDRLI 259
Query: 674 SEPAVVMNTLQKFLKISPHI-DYN 696
+EP + ++KFL + P I YN
Sbjct: 260 TEPLPELQLVEKFLNLPPRISQYN 283
>BC093911-1|AAH93911.1| 346|Homo sapiens heparan sulfate
(glucosamine) 3-O-sulfotransferase 5 protein.
Length = 346
Score = 105 bits (252), Expect = 6e-22
Identities = 66/204 (32%), Positives = 105/204 (51%), Gaps = 12/204 (5%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNN-NYLKGLDWYLNFF 553
LP+ ++IG +K G+ AL L +HP + +E+ FF+N+ NY KG++WY
Sbjct: 90 LPKAIIIGVRKGGTRALLEMLNLHPAVV------KASQEIHFFDNDENYGKGIEWYRKKM 143
Query: 554 PPSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGD 613
P S QIT EKS YF + VP R + + + K++ I+ P+ RA S Y + G
Sbjct: 144 PFSYPQ--QITIEKSPAYFITEEVPERIYKMNSSIKLLIIVREPTTRAISDYTQVLE-GK 200
Query: 614 PIANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLR 673
N + A D ++ + + + + Y+ +LERWL + + Q HV+DG L
Sbjct: 201 ERKNKTYYKFEKLAIDPNTCEV-NTKYKAVRTSIYTKHLERWLKYFPIEQFHVVDGDRLI 259
Query: 674 SEPAVVMNTLQKFLKISPHI-DYN 696
+EP + ++KFL + P I YN
Sbjct: 260 TEPLPELQLVEKFLNLPPRISQYN 283
>AF503292-1|AAN37737.1| 346|Homo sapiens heparan sulfate 3-OST-5
protein.
Length = 346
Score = 105 bits (252), Expect = 6e-22
Identities = 66/204 (32%), Positives = 105/204 (51%), Gaps = 12/204 (5%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNN-NYLKGLDWYLNFF 553
LP+ ++IG +K G+ AL L +HP + +E+ FF+N+ NY KG++WY
Sbjct: 90 LPKAIIIGVRKGGTRALLEMLNLHPAVV------KASQEIHFFDNDENYGKGIEWYRKKM 143
Query: 554 PPSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGD 613
P S QIT EKS YF + VP R + + + K++ I+ P+ RA S Y + G
Sbjct: 144 PFSYPQ--QITIEKSPAYFITEEVPERIYKMNSSIKLLIIVREPTTRAISDYTQVLE-GK 200
Query: 614 PIANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLR 673
N + A D ++ + + + + Y+ +LERWL + + Q HV+DG L
Sbjct: 201 ERKNKTYYKFEKLAIDPNTCEV-NTKYKAVRTSIYTKHLERWLKYFPIEQFHVVDGDRLI 259
Query: 674 SEPAVVMNTLQKFLKISPHI-DYN 696
+EP + ++KFL + P I YN
Sbjct: 260 TEPLPELQLVEKFLNLPPRISQYN 283
>BC057803-1|AAH57803.1| 307|Homo sapiens heparan sulfate
(glucosamine) 3-O-sulfotransferase 1 protein.
Length = 307
Score = 96.3 bits (229), Expect = 4e-19
Identities = 68/247 (27%), Positives = 117/247 (47%), Gaps = 15/247 (6%)
Query: 449 LASAPPLALAEKYFQLRPDELNPLWGNPCDDIRHRRIWSKSKWCGTLPRLLVIGPQKTGS 508
L A P + + +L EL G DD+R + S LP+ ++IG +K G+
Sbjct: 10 LLVAQPQLVPSRTAELGQQELLRKAGTLQDDVRDGVAPNGS--AQQLPQTIIIGVRKGGT 67
Query: 509 TALYTFLAMHPTLKPNLPSPSTYEELQFFN-NNNYLKGLDWYLNFFPPSLTNNSQITFEK 567
AL L++HP + + E+ FF+ +Y GL WYL+ P S + Q+T EK
Sbjct: 68 RALLEMLSLHPDVA------AAENEVHFFDWEEHYSHGLGWYLSQMPFSWPH--QLTVEK 119
Query: 568 SATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDPIANNYTFHTIITA 627
+ YF VP R +++ P+ +++ IL PS+R S Y + + Y
Sbjct: 120 TPAYFTSPKVPERVYSMNPSIRLLLILRDPSERVLSDYTQVFYNHMQKHKPYPSIEEFLV 179
Query: 628 NDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRSEPAVVMNTLQKFL 687
D ++ + LN Y +++ WL + + +H++DG L +P + +++FL
Sbjct: 180 RDGR----LNVDYKALNRSLYHVHMQNWLRFFPLRHIHIVDGDRLIRDPFPEIQKVERFL 235
Query: 688 KISPHID 694
K+SP I+
Sbjct: 236 KLSPQIN 242
>AF019386-1|AAB84388.1| 307|Homo sapiens heparan sulfate
3-O-sulfotransferase-1 precursor protein.
Length = 307
Score = 95.9 bits (228), Expect = 5e-19
Identities = 68/247 (27%), Positives = 117/247 (47%), Gaps = 15/247 (6%)
Query: 449 LASAPPLALAEKYFQLRPDELNPLWGNPCDDIRHRRIWSKSKWCGTLPRLLVIGPQKTGS 508
L A P + + +L EL G DD+R + S LP+ ++IG +K G+
Sbjct: 10 LLVAQPQLVPSRPAELGQQELLRKAGTLQDDVRDGVAPNGS--AQQLPQTIIIGVRKGGT 67
Query: 509 TALYTFLAMHPTLKPNLPSPSTYEELQFFN-NNNYLKGLDWYLNFFPPSLTNNSQITFEK 567
AL L++HP + + E+ FF+ +Y GL WYL+ P S + Q+T EK
Sbjct: 68 RALLEMLSLHPDVA------AAENEVHFFDWEEHYSHGLGWYLSQMPFSWPH--QLTVEK 119
Query: 568 SATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDPIANNYTFHTIITA 627
+ YF VP R +++ P+ +++ IL PS+R S Y + + Y
Sbjct: 120 TPAYFTSPKVPERVYSMNPSIRLLLILRDPSERVLSDYTQVFYNHMQKHKPYPSIEEFLV 179
Query: 628 NDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRSEPAVVMNTLQKFL 687
D ++ + LN Y +++ WL + + +H++DG L +P + +++FL
Sbjct: 180 RDGR----LNVDYKALNRSLYHVHMQNWLRFFPLRHIHIVDGDRLIRDPFPEIQKVERFL 235
Query: 688 KISPHID 694
K+SP I+
Sbjct: 236 KLSPQIN 242
>BC093736-1|AAH93736.1| 367|Homo sapiens heparan sulfate
D-glucosaminyl 3-O-sulfotransferase 2 protein.
Length = 367
Score = 95.1 bits (226), Expect = 9e-19
Identities = 65/199 (32%), Positives = 99/199 (49%), Gaps = 14/199 (7%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ L++G +K G+ A+ F+ +HP ++ P FF+ N Y +GLDWY + P
Sbjct: 114 LPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEP------HFFDRN-YGRGLDWYRSLMP 166
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDP 614
+L SQIT EK+ +YF PRR + + K+I ++ +P RA S Y S
Sbjct: 167 RTL--ESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPD 224
Query: 615 IANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRS 674
I TF + N + L D+ + G Y +LE WL + + Q+H + G L +
Sbjct: 225 IP---TFEGLSFRNRTLG--LVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLIT 279
Query: 675 EPAVVMNTLQKFLKISPHI 693
+PA M +Q FL I I
Sbjct: 280 DPAGEMGRVQDFLGIKRFI 298
Score = 35.5 bits (78), Expect = 0.77
Identities = 17/51 (33%), Positives = 24/51 (47%)
Query: 749 FAFNDDADLKAPKELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHN 799
F FN K+ +CLGKSKGR + ++ LR +Y P+N
Sbjct: 303 FYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYN 353
>BC093734-1|AAH93734.1| 367|Homo sapiens heparan sulfate
(glucosamine) 3-O-sulfotransferase 2 protein.
Length = 367
Score = 95.1 bits (226), Expect = 9e-19
Identities = 65/199 (32%), Positives = 99/199 (49%), Gaps = 14/199 (7%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ L++G +K G+ A+ F+ +HP ++ P FF+ N Y +GLDWY + P
Sbjct: 114 LPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEP------HFFDRN-YGRGLDWYRSLMP 166
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDP 614
+L SQIT EK+ +YF PRR + + K+I ++ +P RA S Y S
Sbjct: 167 RTL--ESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPD 224
Query: 615 IANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRS 674
I TF + N + L D+ + G Y +LE WL + + Q+H + G L +
Sbjct: 225 IP---TFEGLSFRNRTLG--LVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLIT 279
Query: 675 EPAVVMNTLQKFLKISPHI 693
+PA M +Q FL I I
Sbjct: 280 DPAGEMGRVQDFLGIKRFI 298
Score = 35.5 bits (78), Expect = 0.77
Identities = 17/51 (33%), Positives = 24/51 (47%)
Query: 749 FAFNDDADLKAPKELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHN 799
F FN K+ +CLGKSKGR + ++ LR +Y P+N
Sbjct: 303 FYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYN 353
>AY359095-1|AAQ89453.1| 367|Homo sapiens HS3ST2 protein.
Length = 367
Score = 95.1 bits (226), Expect = 9e-19
Identities = 65/199 (32%), Positives = 99/199 (49%), Gaps = 14/199 (7%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ L++G +K G+ A+ F+ +HP ++ P FF+ N Y +GLDWY + P
Sbjct: 114 LPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEP------HFFDRN-YGRGLDWYRSLMP 166
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDP 614
+L SQIT EK+ +YF PRR + + K+I ++ +P RA S Y S
Sbjct: 167 RTL--ESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPD 224
Query: 615 IANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRS 674
I TF + N + L D+ + G Y +LE WL + + Q+H + G L +
Sbjct: 225 IP---TFEGLSFRNRTLG--LVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLIT 279
Query: 675 EPAVVMNTLQKFLKISPHI 693
+PA M +Q FL I I
Sbjct: 280 DPAGEMGRVQDFLGIKRFI 298
Score = 35.5 bits (78), Expect = 0.77
Identities = 17/51 (33%), Positives = 24/51 (47%)
Query: 749 FAFNDDADLKAPKELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHN 799
F FN K+ +CLGKSKGR + ++ LR +Y P+N
Sbjct: 303 FYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYN 353
>AF105375-1|AAD30207.1| 367|Homo sapiens heparan sulfate
D-glucosaminyl 3-O-sulfotransferase-2 protein.
Length = 367
Score = 95.1 bits (226), Expect = 9e-19
Identities = 65/199 (32%), Positives = 99/199 (49%), Gaps = 14/199 (7%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ L++G +K G+ A+ F+ +HP ++ P FF+ N Y +GLDWY + P
Sbjct: 114 LPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEP------HFFDRN-YGRGLDWYRSLMP 166
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDP 614
+L SQIT EK+ +YF PRR + + K+I ++ +P RA S Y S
Sbjct: 167 RTL--ESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPD 224
Query: 615 IANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRS 674
I TF + N + L D+ + G Y +LE WL + + Q+H + G L +
Sbjct: 225 IP---TFEGLSFRNRTLG--LVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLIT 279
Query: 675 EPAVVMNTLQKFLKISPHI 693
+PA M +Q FL I I
Sbjct: 280 DPAGEMGRVQDFLGIKRFI 298
Score = 35.5 bits (78), Expect = 0.77
Identities = 17/51 (33%), Positives = 24/51 (47%)
Query: 749 FAFNDDADLKAPKELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHN 799
F FN K+ +CLGKSKGR + ++ LR +Y P+N
Sbjct: 303 FYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYN 353
>AF105374-1|AAD30206.1| 367|Homo sapiens heparan sulfate
D-glucosaminyl 3-O-sulfotransferase-2 protein.
Length = 367
Score = 95.1 bits (226), Expect = 9e-19
Identities = 65/199 (32%), Positives = 99/199 (49%), Gaps = 14/199 (7%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ L++G +K G+ A+ F+ +HP ++ P FF+ N Y +GLDWY + P
Sbjct: 114 LPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEP------HFFDRN-YGRGLDWYRSLMP 166
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDP 614
+L SQIT EK+ +YF PRR + + K+I ++ +P RA S Y S
Sbjct: 167 RTL--ESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPD 224
Query: 615 IANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRS 674
I TF + N + L D+ + G Y +LE WL + + Q+H + G L +
Sbjct: 225 IP---TFEGLSFRNRTLG--LVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLIT 279
Query: 675 EPAVVMNTLQKFLKISPHI 693
+PA M +Q FL I I
Sbjct: 280 DPAGEMGRVQDFLGIKRFI 298
Score = 35.5 bits (78), Expect = 0.77
Identities = 17/51 (33%), Positives = 24/51 (47%)
Query: 749 FAFNDDADLKAPKELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHN 799
F FN K+ +CLGKSKGR + ++ LR +Y P+N
Sbjct: 303 FYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYN 353
>AB209794-1|BAD93031.1| 345|Homo sapiens heparan sulfate
D-glucosaminyl 3-O-sulfotransferase 2 variant protein.
Length = 345
Score = 95.1 bits (226), Expect = 9e-19
Identities = 65/199 (32%), Positives = 99/199 (49%), Gaps = 14/199 (7%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ L++G +K G+ A+ F+ +HP ++ P FF+ N Y +GLDWY + P
Sbjct: 122 LPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEP------HFFDRN-YGRGLDWYRSLMP 174
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDP 614
+L SQIT EK+ +YF PRR + + K+I ++ +P RA S Y S
Sbjct: 175 RTL--ESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPD 232
Query: 615 IANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRS 674
I TF + N + L D+ + G Y +LE WL + + Q+H + G L +
Sbjct: 233 IP---TFEGLSFRNRTLG--LVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLIT 287
Query: 675 EPAVVMNTLQKFLKISPHI 693
+PA M +Q FL I I
Sbjct: 288 DPAGEMGRVQDFLGIKRFI 306
>AL834283-1|CAD38957.1| 335|Homo sapiens hypothetical protein
protein.
Length = 335
Score = 92.3 bits (219), Expect = 6e-18
Identities = 63/193 (32%), Positives = 98/193 (50%), Gaps = 14/193 (7%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ L+IG +K G+ AL + +HP ++ + E FF+ N Y KGL+WY N P
Sbjct: 76 LPQALIIGVKKGGTRALLEAIRVHPDVR------AVGVEPHFFDRN-YEKGLEWYRNVMP 128
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDP 614
+L + QIT EK+ +YF + P+R H++ + K+I ++ +P RA S Y S
Sbjct: 129 KTL--DGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDYTQTLSKKPE 186
Query: 615 IANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRS 674
I TF + N + L D + G Y+ +LE WL + + Q+ + G L
Sbjct: 187 IP---TFEVLAFKNRTL--GLIDASWSAIRIGIYALHLENWLQYFPLSQILFVSGERLIV 241
Query: 675 EPAVVMNTLQKFL 687
+PA M +Q FL
Sbjct: 242 DPAGEMAKVQDFL 254
Score = 37.9 bits (84), Expect = 0.14
Identities = 18/51 (35%), Positives = 25/51 (49%)
Query: 749 FAFNDDADLKAPKELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHN 799
F FN K+ +CLGKSKGR +P ++ LR++Y P N
Sbjct: 265 FYFNKTKGFPCLKKPEDSSAPRCLGKSKGRTHPRIDPDVIHRLRKFYKPFN 315
>AF105378-1|AAD30210.2| 456|Homo sapiens heparan sulfate
3-O-sulfotransferase-4 protein.
Length = 456
Score = 92.3 bits (219), Expect = 6e-18
Identities = 63/193 (32%), Positives = 98/193 (50%), Gaps = 14/193 (7%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ L+IG +K G+ AL + +HP ++ + E FF+ N Y KGL+WY N P
Sbjct: 197 LPQALIIGVKKGGTRALLEAIRVHPDVR------AVGVEPHFFDRN-YEKGLEWYRNVMP 249
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDP 614
+L + QIT EK+ +YF + P+R H++ + K+I ++ +P RA S Y S
Sbjct: 250 KTL--DGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDYTQTLSKKPE 307
Query: 615 IANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRS 674
I TF + N + L D + G Y+ +LE WL + + Q+ + G L
Sbjct: 308 IP---TFEVLAFKNRTL--GLIDASWSAIRIGIYALHLENWLQYFPLSQILFVSGERLIV 362
Query: 675 EPAVVMNTLQKFL 687
+PA M +Q FL
Sbjct: 363 DPAGEMAKVQDFL 375
Score = 38.3 bits (85), Expect = 0.11
Identities = 18/54 (33%), Positives = 26/54 (48%)
Query: 746 RTRFAFNDDADLKAPKELVGGEKTKCLGKSKGRVYPPMEERSAKFLRRYYTPHN 799
+ F FN K+ +CLGKSKGR +P ++ LR++Y P N
Sbjct: 383 KKHFYFNKTKGFPCLKKPEDSSAPRCLGKSKGRTHPRIDPDVIHRLRKFYKPFN 436
>BC069725-1|AAH69725.1| 390|Homo sapiens heparan sulfate
D-glucosaminyl 3-O-sulfotransferase 3B1 protein.
Length = 390
Score = 91.5 bits (217), Expect = 1e-17
Identities = 63/193 (32%), Positives = 97/193 (50%), Gaps = 14/193 (7%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ ++IG +K G+ AL FL +HP ++ + E FF+ + Y KGL WY + P
Sbjct: 137 LPQAIIIGVKKGGTRALLEFLRVHPDVR------AVGAEPHFFDRS-YDKGLAWYRDLMP 189
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDP 614
+L + QIT EK+ +YF P R A+ + K+I ++ P RA S Y S
Sbjct: 190 RTL--DGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPD 247
Query: 615 IANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRS 674
I TF ++ N +A L D + G Y+ +LE WL + + Q+ + G L S
Sbjct: 248 IP---TFESLTFKNRTAG--LIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERLIS 302
Query: 675 EPAVVMNTLQKFL 687
+PA + +Q FL
Sbjct: 303 DPAGELGRVQDFL 315
Score = 44.0 bits (99), Expect = 0.002
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Query: 724 ERLYGLEVANVGR-RSLVRINNVRT--RFAFNDDADLKAPKELVGGEKTKCLGKSKGRVY 780
ERL +GR + + + + T F FN K+ G + CLGK+KGR +
Sbjct: 298 ERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTH 357
Query: 781 PPMEERSAKFLRRYYTPHN 799
P ++ + LR +Y P N
Sbjct: 358 PEIDREVVRRLREFYRPFN 376
>BC069664-1|AAH69664.1| 390|Homo sapiens heparan sulfate
(glucosamine) 3-O-sulfotransferase 3B1 protein.
Length = 390
Score = 91.5 bits (217), Expect = 1e-17
Identities = 63/193 (32%), Positives = 97/193 (50%), Gaps = 14/193 (7%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ ++IG +K G+ AL FL +HP ++ + E FF+ + Y KGL WY + P
Sbjct: 137 LPQAIIIGVKKGGTRALLEFLRVHPDVR------AVGAEPHFFDRS-YDKGLAWYRDLMP 189
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDP 614
+L + QIT EK+ +YF P R A+ + K+I ++ P RA S Y S
Sbjct: 190 RTL--DGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPD 247
Query: 615 IANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRS 674
I TF ++ N +A L D + G Y+ +LE WL + + Q+ + G L S
Sbjct: 248 IP---TFESLTFKNRTAG--LIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERLIS 302
Query: 675 EPAVVMNTLQKFL 687
+PA + +Q FL
Sbjct: 303 DPAGELGRVQDFL 315
Score = 44.0 bits (99), Expect = 0.002
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Query: 724 ERLYGLEVANVGR-RSLVRINNVRT--RFAFNDDADLKAPKELVGGEKTKCLGKSKGRVY 780
ERL +GR + + + + T F FN K+ G + CLGK+KGR +
Sbjct: 298 ERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTH 357
Query: 781 PPMEERSAKFLRRYYTPHN 799
P ++ + LR +Y P N
Sbjct: 358 PEIDREVVRRLREFYRPFN 376
>BC063301-1|AAH63301.1| 390|Homo sapiens heparan sulfate
(glucosamine) 3-O-sulfotransferase 3B1 protein.
Length = 390
Score = 91.5 bits (217), Expect = 1e-17
Identities = 63/193 (32%), Positives = 97/193 (50%), Gaps = 14/193 (7%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ ++IG +K G+ AL FL +HP ++ + E FF+ + Y KGL WY + P
Sbjct: 137 LPQAIIIGVKKGGTRALLEFLRVHPDVR------AVGAEPHFFDRS-YDKGLAWYRDLMP 189
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDP 614
+L + QIT EK+ +YF P R A+ + K+I ++ P RA S Y S
Sbjct: 190 RTL--DGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPD 247
Query: 615 IANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRS 674
I TF ++ N +A L D + G Y+ +LE WL + + Q+ + G L S
Sbjct: 248 IP---TFESLTFKNRTAG--LIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERLIS 302
Query: 675 EPAVVMNTLQKFL 687
+PA + +Q FL
Sbjct: 303 DPAGELGRVQDFL 315
Score = 44.0 bits (99), Expect = 0.002
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Query: 724 ERLYGLEVANVGR-RSLVRINNVRT--RFAFNDDADLKAPKELVGGEKTKCLGKSKGRVY 780
ERL +GR + + + + T F FN K+ G + CLGK+KGR +
Sbjct: 298 ERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTH 357
Query: 781 PPMEERSAKFLRRYYTPHN 799
P ++ + LR +Y P N
Sbjct: 358 PEIDREVVRRLREFYRPFN 376
>BC044647-1|AAH44647.1| 406|Homo sapiens heparan sulfate
(glucosamine) 3-O-sulfotransferase 3A1 protein.
Length = 406
Score = 91.5 bits (217), Expect = 1e-17
Identities = 63/193 (32%), Positives = 97/193 (50%), Gaps = 14/193 (7%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ ++IG +K G+ AL FL +HP ++ + E FF+ + Y KGL WY + P
Sbjct: 152 LPQAIIIGVKKGGTRALLEFLRVHPDVR------AVGAEPHFFDRS-YDKGLAWYRDLMP 204
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDP 614
+L + QIT EK+ +YF P R A+ + K+I ++ P RA S Y S
Sbjct: 205 RTL--DGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPD 262
Query: 615 IANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRS 674
I TF ++ N +A L D + G Y+ +LE WL + + Q+ + G L S
Sbjct: 263 IP---TFESLTFKNRTAG--LIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERLIS 317
Query: 675 EPAVVMNTLQKFL 687
+PA + +Q FL
Sbjct: 318 DPAGELGRVQDFL 330
Score = 44.0 bits (99), Expect = 0.002
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Query: 724 ERLYGLEVANVGR-RSLVRINNVRT--RFAFNDDADLKAPKELVGGEKTKCLGKSKGRVY 780
ERL +GR + + + + T F FN K+ G + CLGK+KGR +
Sbjct: 313 ERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTH 372
Query: 781 PPMEERSAKFLRRYYTPHN 799
P ++ + LR +Y P N
Sbjct: 373 PEIDREVVRRLREFYRPFN 391
>AY358838-1|AAQ89197.1| 406|Homo sapiens HS3ST3A1 protein.
Length = 406
Score = 91.5 bits (217), Expect = 1e-17
Identities = 63/193 (32%), Positives = 97/193 (50%), Gaps = 14/193 (7%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ ++IG +K G+ AL FL +HP ++ + E FF+ + Y KGL WY + P
Sbjct: 152 LPQAIIIGVKKGGTRALLEFLRVHPDVR------AVGAEPHFFDRS-YDKGLAWYRDLMP 204
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDP 614
+L + QIT EK+ +YF P R A+ + K+I ++ P RA S Y S
Sbjct: 205 RTL--DGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPD 262
Query: 615 IANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRS 674
I TF ++ N +A L D + G Y+ +LE WL + + Q+ + G L S
Sbjct: 263 IP---TFESLTFKNRTAG--LIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERLIS 317
Query: 675 EPAVVMNTLQKFL 687
+PA + +Q FL
Sbjct: 318 DPAGELGRVQDFL 330
Score = 44.0 bits (99), Expect = 0.002
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Query: 724 ERLYGLEVANVGR-RSLVRINNVRT--RFAFNDDADLKAPKELVGGEKTKCLGKSKGRVY 780
ERL +GR + + + + T F FN K+ G + CLGK+KGR +
Sbjct: 313 ERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTH 372
Query: 781 PPMEERSAKFLRRYYTPHN 799
P ++ + LR +Y P N
Sbjct: 373 PEIDREVVRRLREFYRPFN 391
>AF105377-1|AAD30209.1| 390|Homo sapiens heparan sulfate
D-glucosaminyl 3-O-sulfotransferase-3B protein.
Length = 390
Score = 91.5 bits (217), Expect = 1e-17
Identities = 63/193 (32%), Positives = 97/193 (50%), Gaps = 14/193 (7%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ ++IG +K G+ AL FL +HP ++ + E FF+ + Y KGL WY + P
Sbjct: 137 LPQAIIIGVKKGGTRALLEFLRVHPDVR------AVGAEPHFFDRS-YDKGLAWYRDLMP 189
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDP 614
+L + QIT EK+ +YF P R A+ + K+I ++ P RA S Y S
Sbjct: 190 RTL--DGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPD 247
Query: 615 IANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRS 674
I TF ++ N +A L D + G Y+ +LE WL + + Q+ + G L S
Sbjct: 248 IP---TFESLTFKNRTAG--LIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERLIS 302
Query: 675 EPAVVMNTLQKFL 687
+PA + +Q FL
Sbjct: 303 DPAGELGRVQDFL 315
Score = 44.0 bits (99), Expect = 0.002
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Query: 724 ERLYGLEVANVGR-RSLVRINNVRT--RFAFNDDADLKAPKELVGGEKTKCLGKSKGRVY 780
ERL +GR + + + + T F FN K+ G + CLGK+KGR +
Sbjct: 298 ERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTH 357
Query: 781 PPMEERSAKFLRRYYTPHN 799
P ++ + LR +Y P N
Sbjct: 358 PEIDREVVRRLREFYRPFN 376
>AF105376-1|AAD30208.1| 406|Homo sapiens heparan sulfate
D-glucosaminyl 3-O-sulfotransferase-3A protein.
Length = 406
Score = 91.5 bits (217), Expect = 1e-17
Identities = 63/193 (32%), Positives = 97/193 (50%), Gaps = 14/193 (7%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ ++IG +K G+ AL FL +HP ++ + E FF+ + Y KGL WY + P
Sbjct: 152 LPQAIIIGVKKGGTRALLEFLRVHPDVR------AVGAEPHFFDRS-YDKGLAWYRDLMP 204
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDP 614
+L + QIT EK+ +YF P R A+ + K+I ++ P RA S Y S
Sbjct: 205 RTL--DGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPD 262
Query: 615 IANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRS 674
I TF ++ N +A L D + G Y+ +LE WL + + Q+ + G L S
Sbjct: 263 IP---TFESLTFKNRTAG--LIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERLIS 317
Query: 675 EPAVVMNTLQKFL 687
+PA + +Q FL
Sbjct: 318 DPAGELGRVQDFL 330
Score = 44.0 bits (99), Expect = 0.002
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Query: 724 ERLYGLEVANVGR-RSLVRINNVRT--RFAFNDDADLKAPKELVGGEKTKCLGKSKGRVY 780
ERL +GR + + + + T F FN K+ G + CLGK+KGR +
Sbjct: 313 ERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTH 372
Query: 781 PPMEERSAKFLRRYYTPHN 799
P ++ + LR +Y P N
Sbjct: 373 PEIDREVVRRLREFYRPFN 391
>AL031723-1|CAC42157.1| 381|Homo sapiens protein ( Human DNA
sequence from clone LA16c-439A6 on chromosome 16. ).
Length = 381
Score = 85.8 bits (203), Expect = 6e-16
Identities = 58/192 (30%), Positives = 94/192 (48%), Gaps = 15/192 (7%)
Query: 496 PRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFPP 555
P+ L++G +K G+ AL FL +HP ++ + E FF+ Y +GL WY + P
Sbjct: 130 PQALIVGVKKGGTRALLEFLRLHPDVR------ALGSEPHFFDRC-YERGLAWYRSLMPR 182
Query: 556 SLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDPI 615
+L + QIT EK+ +YF PRR HA+ P+ K+I ++ +P RA S Y S +
Sbjct: 183 TL--DGQITMEKTPSYFVTREAPRRIHAMSPDTKLIVVVRNPVTRAISDYAQTLSKTPGL 240
Query: 616 ANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRSE 675
+F + + P D + G Y+ +L+ WL + + + G L S+
Sbjct: 241 P---SFRALAFRHGLGPV---DTAWSAVRIGLYAQHLDHWLRYFPLSHFLFVSGERLVSD 294
Query: 676 PAVVMNTLQKFL 687
PA + +Q FL
Sbjct: 295 PAGEVGRVQDFL 306
Score = 46.4 bits (105), Expect = 4e-04
Identities = 27/79 (34%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Query: 724 ERLYGLEVANVGR-RSLVRINNVRT--RFAFNDDADLKAPKELVGGEKTKCLGKSKGRVY 780
ERL VGR + + + V T F FN K+ GG + +CLGKSKGR +
Sbjct: 289 ERLVSDPAGEVGRVQDFLGLKRVVTDKHFYFNATKGFPCLKKAQGGSRPRCLGKSKGRPH 348
Query: 781 PPMEERSAKFLRRYYTPHN 799
P + + + L+ +Y P N
Sbjct: 349 PRVPQALVRRLQEFYRPFN 367
>AE006640-3|AAK61299.1| 311|Homo sapiens heparan sulphate
D-glucosaminyl 3-O-sulfotransferase-3B like protein.
Length = 311
Score = 85.8 bits (203), Expect = 6e-16
Identities = 58/192 (30%), Positives = 94/192 (48%), Gaps = 15/192 (7%)
Query: 496 PRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFPP 555
P+ L++G +K G+ AL FL +HP ++ + E FF+ Y +GL WY + P
Sbjct: 60 PQALIVGVKKGGTRALLEFLRLHPDVR------ALGSEPHFFDRC-YERGLAWYRSLMPR 112
Query: 556 SLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWYQHIRSHGDPI 615
+L + QIT EK+ +YF PRR HA+ P+ K+I ++ +P RA S Y S +
Sbjct: 113 TL--DGQITMEKTPSYFVTREAPRRIHAMSPDTKLIVVVRNPVTRAISDYTQTLSKTPGL 170
Query: 616 ANNYTFHTIITANDSAPKQLRDLRNRCLNPGKYSHYLERWLSEYSVHQLHVIDGSMLRSE 675
+F + + P D + G Y+ +L+ WL + + + G L S+
Sbjct: 171 P---SFRALAFRHGLGPV---DTAWSAVRIGLYAQHLDHWLRYFPLSHFLFVSGERLVSD 224
Query: 676 PAVVMNTLQKFL 687
PA + +Q FL
Sbjct: 225 PAGEVGRVQDFL 236
Score = 46.4 bits (105), Expect = 4e-04
Identities = 27/79 (34%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Query: 724 ERLYGLEVANVGR-RSLVRINNVRT--RFAFNDDADLKAPKELVGGEKTKCLGKSKGRVY 780
ERL VGR + + + V T F FN K+ GG + +CLGKSKGR +
Sbjct: 219 ERLVSDPAGEVGRVQDFLGLKRVVTDKHFYFNATKGFPCLKKAQGGSRPRCLGKSKGRPH 278
Query: 781 PPMEERSAKFLRRYYTPHN 799
P + + + L+ +Y P N
Sbjct: 279 PRVPQAVVRRLQEFYRPFN 297
>EF063608-1|ABN79919.1| 139|Homo sapiens heparan sulfate
3-O-sulfotransferase 4 protein.
Length = 139
Score = 72.5 bits (170), Expect = 6e-12
Identities = 41/111 (36%), Positives = 65/111 (58%), Gaps = 9/111 (8%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ L+IG +K G+ AL + +HP ++ + E FF+ N Y KGL+WY N P
Sbjct: 18 LPQALIIGVKKGGTRALLEAIRVHPDVR------AVGVEPHFFDRN-YEKGLEWYRNVMP 70
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWY 605
+L + QIT EK+ +YF + P+R H++ + K+I ++ +P RA S Y
Sbjct: 71 KTL--DGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDY 119
>EF063607-1|ABN79918.1| 139|Homo sapiens heparan sulfate
3-O-sulfotransferase 4 protein.
Length = 139
Score = 72.5 bits (170), Expect = 6e-12
Identities = 41/111 (36%), Positives = 65/111 (58%), Gaps = 9/111 (8%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ L+IG +K G+ AL + +HP ++ + E FF+ N Y KGL+WY N P
Sbjct: 18 LPQALIIGVKKGGTRALLEAIRVHPDVR------AVGVEPHFFDRN-YEKGLEWYRNVMP 70
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWY 605
+L + QIT EK+ +YF + P+R H++ + K+I ++ +P RA S Y
Sbjct: 71 KTL--DGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDY 119
>EF063606-1|ABN79917.1| 139|Homo sapiens heparan sulfate
3-O-sulfotransferase 4 protein.
Length = 139
Score = 72.5 bits (170), Expect = 6e-12
Identities = 41/111 (36%), Positives = 65/111 (58%), Gaps = 9/111 (8%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ L+IG +K G+ AL + +HP ++ + E FF+ N Y KGL+WY N P
Sbjct: 18 LPQALIIGVKKGGTRALLEAIRVHPDVR------AVGVEPHFFDRN-YEKGLEWYRNVMP 70
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWY 605
+L + QIT EK+ +YF + P+R H++ + K+I ++ +P RA S Y
Sbjct: 71 KTL--DGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDY 119
>EF063605-1|ABN79916.1| 139|Homo sapiens heparan sulfate
3-O-sulfotransferase 4 protein.
Length = 139
Score = 72.5 bits (170), Expect = 6e-12
Identities = 41/111 (36%), Positives = 65/111 (58%), Gaps = 9/111 (8%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ L+IG +K G+ AL + +HP ++ + E FF+ N Y KGL+WY N P
Sbjct: 18 LPQALIIGVKKGGTRALLEAIRVHPDVR------AVGVEPHFFDRN-YEKGLEWYRNVMP 70
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWY 605
+L + QIT EK+ +YF + P+R H++ + K+I ++ +P RA S Y
Sbjct: 71 KTL--DGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDY 119
>EF063604-1|ABN79915.1| 139|Homo sapiens heparan sulfate
3-O-sulfotransferase 4 protein.
Length = 139
Score = 72.5 bits (170), Expect = 6e-12
Identities = 41/111 (36%), Positives = 65/111 (58%), Gaps = 9/111 (8%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ L+IG +K G+ AL + +HP ++ + E FF+ N Y KGL+WY N P
Sbjct: 18 LPQALIIGVKKGGTRALLEAIRVHPDVR------AVGVEPHFFDRN-YEKGLEWYRNVMP 70
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWY 605
+L + QIT EK+ +YF + P+R H++ + K+I ++ +P RA S Y
Sbjct: 71 KTL--DGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDY 119
>EF063603-1|ABN79914.1| 139|Homo sapiens heparan sulfate
3-O-sulfotransferase 4 protein.
Length = 139
Score = 72.5 bits (170), Expect = 6e-12
Identities = 41/111 (36%), Positives = 65/111 (58%), Gaps = 9/111 (8%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ L+IG +K G+ AL + +HP ++ + E FF+ N Y KGL+WY N P
Sbjct: 18 LPQALIIGVKKGGTRALLEAIRVHPDVR------AVGVEPHFFDRN-YEKGLEWYRNVMP 70
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWY 605
+L + QIT EK+ +YF + P+R H++ + K+I ++ +P RA S Y
Sbjct: 71 KTL--DGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDY 119
>EF063602-1|ABN79913.1| 139|Homo sapiens heparan sulfate
3-O-sulfotransferase 4 protein.
Length = 139
Score = 72.5 bits (170), Expect = 6e-12
Identities = 41/111 (36%), Positives = 65/111 (58%), Gaps = 9/111 (8%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ L+IG +K G+ AL + +HP ++ + E FF+ N Y KGL+WY N P
Sbjct: 18 LPQALIIGVKKGGTRALLEAIRVHPDVR------AVGVEPHFFDRN-YEKGLEWYRNVMP 70
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWY 605
+L + QIT EK+ +YF + P+R H++ + K+I ++ +P RA S Y
Sbjct: 71 KTL--DGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDY 119
>EF063601-1|ABN79912.1| 139|Homo sapiens heparan sulfate
3-O-sulfotransferase 4 protein.
Length = 139
Score = 72.5 bits (170), Expect = 6e-12
Identities = 41/111 (36%), Positives = 65/111 (58%), Gaps = 9/111 (8%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWYLNFFP 554
LP+ L+IG +K G+ AL + +HP ++ + E FF+ N Y KGL+WY N P
Sbjct: 18 LPQALIIGVKKGGTRALLEAIRVHPDVR------AVGVEPHFFDRN-YEKGLEWYRNVMP 70
Query: 555 PSLTNNSQITFEKSATYFDGDLVPRRAHALLPNAKIIAILISPSKRAYSWY 605
+L + QIT EK+ +YF + P+R H++ + K+I ++ +P RA S Y
Sbjct: 71 KTL--DGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDY 119
>AK091074-1|BAC03577.1| 175|Homo sapiens protein ( Homo sapiens
cDNA FLJ33755 fis, clone BRCAN2000523. ).
Length = 175
Score = 52.8 bits (121), Expect = 5e-06
Identities = 32/109 (29%), Positives = 54/109 (49%), Gaps = 3/109 (2%)
Query: 589 KIIAILISPSKRAYSWYQHIRSHGDPIANNYTFHTIITANDSAPKQLRDLRNRCLNPGKY 648
K++ I+ P+ RA S Y + G N + A D ++ + + + + Y
Sbjct: 6 KLLIIVREPTTRAISDYTQVLE-GKERKNKTYYKFEKLAIDPNTCEV-NTKYKAVRTSIY 63
Query: 649 SHYLERWLSEYSVHQLHVIDGSMLRSEPAVVMNTLQKFLKISPHI-DYN 696
+ +LERWL + + Q HV+DG L +EP + ++KFL + P I YN
Sbjct: 64 TKHLERWLKYFPIEQFHVVDGDRLITEPLPELQLVEKFLNLPPRISQYN 112
>AY476736-1|AAS58324.1| 244|Homo sapiens heparan sulfate
3-O-sulfotransferase-4 protein.
Length = 244
Score = 37.5 bits (83), Expect = 0.19
Identities = 21/55 (38%), Positives = 32/55 (58%), Gaps = 7/55 (12%)
Query: 495 LPRLLVIGPQKTGSTALYTFLAMHPTLKPNLPSPSTYEELQFFNNNNYLKGLDWY 549
LP+ L+IG +K G+ AL + +HP ++ + E FF + NY KGL+WY
Sbjct: 197 LPQALIIGVKKGGTRALLEAIRVHPDVR------AVGVEPHFF-DRNYEKGLEWY 244
>M73240-1|AAA64297.1| 723|Homo sapiens hepatocyte growth factor
protein.
Length = 723
Score = 31.9 bits (69), Expect = 9.5
Identities = 20/84 (23%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Query: 268 LLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMMLNKQFALE-HGIPTNSCYSVSPHHSG 326
L+ H E C W+HQ PH + + + + + + G P CY++ PH
Sbjct: 217 LMDHTESGK-ICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRW 275
Query: 327 VYPVHEPLYEAWRKVWDVKVTSTE 350
Y + + DV + +TE
Sbjct: 276 EYCAIKTCADNTMNDTDVPLETTE 299
>M73239-1|AAA64239.1| 728|Homo sapiens hepatocyte growth factor
protein.
Length = 728
Score = 31.9 bits (69), Expect = 9.5
Identities = 20/84 (23%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Query: 268 LLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMMLNKQFALE-HGIPTNSCYSVSPHHSG 326
L+ H E C W+HQ PH + + + + + + G P CY++ PH
Sbjct: 222 LMDHTESGK-ICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRW 280
Query: 327 VYPVHEPLYEAWRKVWDVKVTSTE 350
Y + + DV + +TE
Sbjct: 281 EYCAIKTCADNTMNDTDVPLETTE 304
>M60718-1|AAA52648.1| 728|Homo sapiens hepatocyte growth factor
protein.
Length = 728
Score = 31.9 bits (69), Expect = 9.5
Identities = 20/84 (23%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Query: 268 LLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMMLNKQFALE-HGIPTNSCYSVSPHHSG 326
L+ H E C W+HQ PH + + + + + + G P CY++ PH
Sbjct: 222 LMDHTESGK-ICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRW 280
Query: 327 VYPVHEPLYEAWRKVWDVKVTSTE 350
Y + + DV + +TE
Sbjct: 281 EYCAIKTCADNTMNDTDVPLETTE 304
>M29145-1|AAA52650.1| 728|Homo sapiens HGF protein.
Length = 728
Score = 31.9 bits (69), Expect = 9.5
Identities = 20/84 (23%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Query: 268 LLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMMLNKQFALE-HGIPTNSCYSVSPHHSG 326
L+ H E C W+HQ PH + + + + + + G P CY++ PH
Sbjct: 222 LMDHTESGK-ICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRW 280
Query: 327 VYPVHEPLYEAWRKVWDVKVTSTE 350
Y + + DV + +TE
Sbjct: 281 EYCAIKTCADNTMNDTDVPLETTE 304
>D90334-1|BAA14348.1| 728|Homo sapiens hepatocyte growth factor
protein.
Length = 728
Score = 31.9 bits (69), Expect = 9.5
Identities = 20/84 (23%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Query: 268 LLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMMLNKQFALE-HGIPTNSCYSVSPHHSG 326
L+ H E C W+HQ PH + + + + + + G P CY++ PH
Sbjct: 222 LMDHTESGK-ICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRW 280
Query: 327 VYPVHEPLYEAWRKVWDVKVTSTE 350
Y + + DV + +TE
Sbjct: 281 EYCAIKTCADNTMNDTDVPLETTE 304
>BC130286-1|AAI30287.1| 728|Homo sapiens hepatocyte growth factor
(hepapoietin A; scatter factor) protein.
Length = 728
Score = 31.9 bits (69), Expect = 9.5
Identities = 20/84 (23%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Query: 268 LLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMMLNKQFALE-HGIPTNSCYSVSPHHSG 326
L+ H E C W+HQ PH + + + + + + G P CY++ PH
Sbjct: 222 LMDHTESGK-ICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRW 280
Query: 327 VYPVHEPLYEAWRKVWDVKVTSTE 350
Y + + DV + +TE
Sbjct: 281 EYCAIKTCADNTMNDTDVPLETTE 304
>BC130284-1|AAI30285.1| 728|Homo sapiens hepatocyte growth factor
(hepapoietin A; scatter factor) protein.
Length = 728
Score = 31.9 bits (69), Expect = 9.5
Identities = 20/84 (23%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Query: 268 LLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMMLNKQFALE-HGIPTNSCYSVSPHHSG 326
L+ H E C W+HQ PH + + + + + + G P CY++ PH
Sbjct: 222 LMDHTESGK-ICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRW 280
Query: 327 VYPVHEPLYEAWRKVWDVKVTSTE 350
Y + + DV + +TE
Sbjct: 281 EYCAIKTCADNTMNDTDVPLETTE 304
>AY246560-1|AAO61091.1| 728|Homo sapiens hepatocyte growth factor
(hepapoietin A; scatter factor) protein.
Length = 728
Score = 31.9 bits (69), Expect = 9.5
Identities = 20/84 (23%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Query: 268 LLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMMLNKQFALE-HGIPTNSCYSVSPHHSG 326
L+ H E C W+HQ PH + + + + + + G P CY++ PH
Sbjct: 222 LMDHTESGK-ICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRW 280
Query: 327 VYPVHEPLYEAWRKVWDVKVTSTE 350
Y + + DV + +TE
Sbjct: 281 EYCAIKTCADNTMNDTDVPLETTE 304
>AC004960-1|AAC71655.1| 723|Homo sapiens hepatocyte growth factor
protein.
Length = 723
Score = 31.9 bits (69), Expect = 9.5
Identities = 20/84 (23%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Query: 268 LLKHREYFNWFCHMWNHQQPHLYNNVSQLEAEMMLNKQFALE-HGIPTNSCYSVSPHHSG 326
L+ H E C W+HQ PH + + + + + + G P CY++ PH
Sbjct: 217 LMDHTESGK-ICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRW 275
Query: 327 VYPVHEPLYEAWRKVWDVKVTSTE 350
Y + + DV + +TE
Sbjct: 276 EYCAIKTCADNTMNDTDVPLETTE 299
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.137 0.432
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 131,792,135
Number of Sequences: 224733
Number of extensions: 5878490
Number of successful extensions: 9835
Number of sequences better than 10.0: 61
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 9639
Number of HSP's gapped (non-prelim): 105
length of query: 825
length of database: 73,234,838
effective HSP length: 96
effective length of query: 729
effective length of database: 51,660,470
effective search space: 37660482630
effective search space used: 37660482630
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 69 (31.9 bits)
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