BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000420-TA|BGIBMGA000420-PA|IPR000719|Protein kinase, IPR011009|Protein kinase-like, IPR008271|Serine/threonine protein kinase, active site, IPR002290|Serine/threonine protein kinase (484 letters) Database: spombe 5004 sequences; 2,362,478 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schiz... 140 3e-34 SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Pp... 120 6e-28 SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosa... 117 4e-27 SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosa... 117 4e-27 SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces ... 113 4e-26 SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |S... 113 7e-26 SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccha... 110 5e-25 SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Sch... 109 8e-25 SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizos... 107 5e-24 SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosacc... 105 2e-23 SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |S... 103 4e-23 SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc... 103 6e-23 SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1... 102 1e-22 SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosacch... 101 2e-22 SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizo... 101 3e-22 SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|c... 101 3e-22 SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosac... 99 7e-22 SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosacc... 98 3e-21 SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schiz... 95 1e-20 SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosa... 95 2e-20 SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosac... 94 4e-20 SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|... 93 6e-20 SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1||... 93 8e-20 SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schi... 93 1e-19 SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2... 91 2e-19 SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharom... 91 2e-19 SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces... 91 2e-19 SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating ... 91 4e-19 SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomy... 90 6e-19 SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|ch... 89 1e-18 SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyc... 89 2e-18 SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizos... 88 3e-18 SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizos... 87 4e-18 SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosa... 87 5e-18 SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosac... 86 1e-17 SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase P... 85 2e-17 SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Sc... 85 3e-17 SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosacch... 85 3e-17 SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosacchar... 84 4e-17 SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizos... 84 5e-17 SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccha... 84 5e-17 SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe... 83 6e-17 SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalyt... 82 1e-16 SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase... 82 2e-16 SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Sch... 81 3e-16 SPCC63.08c |ppk36|atg1|serine/threonine protein kinase Ppk36|Sch... 80 8e-16 SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizo... 78 2e-15 SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity prote... 76 1e-14 SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizos... 75 2e-14 SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase ki... 75 2e-14 SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase S... 75 2e-14 SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyc... 74 5e-14 SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein k... 73 7e-14 SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gc... 73 9e-14 SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosa... 73 1e-13 SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizo... 72 2e-13 SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosa... 71 5e-13 SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizo... 71 5e-13 SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces po... 69 1e-12 SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizos... 69 1e-12 SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |S... 69 2e-12 SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccha... 69 2e-12 SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase ... 69 2e-12 SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosac... 68 3e-12 SPBC337.04 |ppk27||serine/threonine protein kinase Ppk27 |Schizo... 62 1e-10 SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Sch... 62 2e-10 SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomy... 61 3e-10 SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizos... 61 4e-10 SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosa... 61 4e-10 SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schiz... 60 9e-10 SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizo... 60 9e-10 SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosacchar... 58 2e-09 SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Sch... 58 3e-09 SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schi... 57 6e-09 SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosacchar... 54 3e-08 SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosa... 54 4e-08 SPAC23A1.06c |cmk2|mkp2|MAPK-activated protein kinase Cmk2|Schiz... 54 6e-08 SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk... 53 8e-08 SPAC823.03 |ppk15||serine/threonine protein kinase Ppk15 |Schizo... 53 8e-08 SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |... 52 2e-07 SPCC1322.08 |srk1|mkp1|MAPK-activated protein kinase Srk1|Schizo... 51 4e-07 SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|S... 50 5e-07 SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomy... 50 7e-07 SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosac... 50 1e-06 SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizos... 48 2e-06 SPBP23A10.10 |ppk32||serine/threonine protein kinase Ppk32 |Schi... 48 4e-06 SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schi... 48 4e-06 SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizos... 47 5e-06 SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosac... 46 1e-05 SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosa... 45 2e-05 SPBC530.14c |dsk1||SR protein-specific kinase Dsk1|Schizosacchar... 44 5e-05 SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizos... 43 1e-04 SPAC3H1.13 |ppk13||serine/threonine protein kinase Ppk13 |Schizo... 42 2e-04 SPBC21C3.18 |spo4||serine/threonine protein kinase Spo4|Schizosa... 42 2e-04 SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosac... 42 3e-04 SPBC336.14c |ppk26||serine/threonine protein kinase Ppk26|Schizo... 39 0.001 SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizo... 38 0.002 SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces po... 38 0.002 SPBC119.07 |ppk19||serine/threonine protein kinase Ppk19|Schizos... 36 0.010 SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizos... 36 0.013 SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizos... 34 0.039 SPAC1805.05 |cki3||serine/threonine protein kinase Cki3|Schizosa... 34 0.051 SPAC27E2.09 |mak2|phk1|histidine kinase Mak2 |Schizosaccharomyce... 32 0.21 SPAC20G4.03c |hri1||eIF2 alpha kinase Hri1|Schizosaccharomyces p... 32 0.21 SPAC12B10.14c |ppk2||serine/threonine protein kinase Ppk2 |Schiz... 29 1.4 SPAC227.04 |||autophagy C terminal domain family protein|Schizos... 27 5.8 SPBC577.09 |||ERCC-8 homolog |Schizosaccharomyces pombe|chr 2|||... 27 7.7 SPBC21H7.02 |taf10||transcription factor TFIID complex subunit T... 27 7.7 >SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schizosaccharomyces pombe|chr 3|||Manual Length = 576 Score = 140 bits (340), Expect = 3e-34 Identities = 81/270 (30%), Positives = 136/270 (50%), Gaps = 10/270 (3%) Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150 +G Y++ + LGEGS+GKVK + ++ + V+REI L++L Sbjct: 31 IGPYIIRETLGEGSFGKVK-LATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLL 89 Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLD 210 RH ++I+L DVI + +V+E+ G L D + K+ + + +F Q++ ++ Sbjct: 90 RHPHIIKLYDVITTPTD--IVMVIEYAGGELFDYIVEK--KRMTEDEGRRFFQQIICAIE 145 Query: 211 YLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIA 270 Y H +VH+D+KP NLLL + +KI DFG++ ++ + + T GSP + PE+ Sbjct: 146 YCHRHKIVHRDLKPENLLLDDNLNVKIADFGLS---NIMTDGNFLKTSCGSPNYAAPEVI 202 Query: 271 NGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXX 330 NG + ++G +VD+WS G+ LY M GR PF+ + + L + ++ Sbjct: 203 NG-KLYAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVN-SCVYVMPDFLSPGAQS 260 Query: 331 XXXHMLNRDPTLRPTVHEIRRHAWVQATPP 360 M+ DP R T+ EIRR W P Sbjct: 261 LIRRMIVADPMQRITIQEIRRDPWFNVNLP 290 >SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Ppk34|Schizosaccharomyces pombe|chr 3|||Manual Length = 354 Score = 120 bits (288), Expect = 6e-28 Identities = 65/214 (30%), Positives = 109/214 (50%), Gaps = 6/214 (2%) Query: 140 VQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQA 198 +++E+ +L++L H+NV++L VI +D K + +V+ +C G L + P Sbjct: 118 IRKELDVLKVLDHENVVKLYQVINSDYKDSLCMVLNYCPGGKLASVDHGISFDPMPLETC 177 Query: 199 HDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTG 258 F QL+ ++Y+HG+GV+H+DIKP N+L + L + DFG+AE L ++ Sbjct: 178 RKSFRQLVLAVNYIHGKGVIHRDIKPDNILFKENNNLCVIDFGLAEFL---PKDGFVKPA 234 Query: 259 QGSPAFQPPEI-ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXX 317 G+PAF PE+ N ++ G +DIWS GVTLY + +PF G + ++ I + Sbjct: 235 SGTPAFMAPELFDNELKKIKGKPLDIWSMGVTLYVIAFAEFPFNGSTILDMINVI-KGKS 293 Query: 318 XXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRR 351 L ++P R T+ E+ R Sbjct: 294 LMIPAYCNSDLRKLLERCLEKNPEKRITIEELLR 327 >SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosaccharomyces pombe|chr 3|||Manual Length = 652 Score = 117 bits (281), Expect = 4e-27 Identities = 85/282 (30%), Positives = 132/282 (46%), Gaps = 19/282 (6%) Query: 89 KMVGKYVMGDVLGEGSYGKVK---EMLDSQSLCRRAVXXXXXXXXXXXPNG---EQNVQR 142 K + Y + LG G +GKVK + + + L + + N ++ V+R Sbjct: 130 KYINHYEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKTERRPKLGRANASSQKEKVRR 189 Query: 143 EIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLE-SSPGKKFPQRQAHDY 201 EI +L+ H NV+ L +VI + K+YLV+E+ G + SP + A Y Sbjct: 190 EIAILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISE--ARQY 247 Query: 202 FLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQED----ICYT 257 F ++ GL+YLH QG++H+DIKP NLLL +KI+DFGV+ + ED + T Sbjct: 248 FRDVVLGLEYLHYQGIIHRDIKPANLLLNSSNCVKISDFGVSYIANAGLNEDNDVELAKT 307 Query: 258 GQGSPAFQPPEIA----NGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI- 312 G+PAF PE+ + +D+W+ GVTL+ + GR PF Y L + I Sbjct: 308 -VGTPAFFAPELCWTDLDRPRPKISEAIDVWALGVTLFCLLFGRCPFNASMEYELFDKIV 366 Query: 313 SRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAW 354 + +L +DP R T+ E++ H W Sbjct: 367 NERLNIPSTPDIGEEGRDLLKRLLCKDPEQRITLVEVKLHPW 408 >SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosaccharomyces pombe|chr 3|||Manual Length = 355 Score = 117 bits (281), Expect = 4e-27 Identities = 77/266 (28%), Positives = 128/266 (48%), Gaps = 12/266 (4%) Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150 +G + +G LG+G +G+V + ++ A+ E+ V+REI++ L Sbjct: 86 IGMFEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKI-EKQVRREIEIQSNL 144 Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209 RHKN++ L ++DEK ++YL++EF G L L + K+F + A Y Q+ + L Sbjct: 145 RHKNILRLYGH-FHDEK-RIYLILEFAGRGELYQHLRRA--KRFSEEVASKYIFQMANAL 200 Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269 YLH + V+H+DIKP N+LL +D +K++DFG + + +C G+ + PPE+ Sbjct: 201 SYLHKKHVIHRDIKPENILLGIDGEIKLSDFGWSVHAPSNRRTTLC----GTLDYLPPEM 256 Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329 G E KVD+WS GV Y G PFE + + Sbjct: 257 VEGKEHTE--KVDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKIPSFVPPDAR 314 Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWV 355 +L +P R ++ ++ RH W+ Sbjct: 315 DLISRLLQHNPEKRMSLEQVMRHPWI 340 >SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces pombe|chr 3|||Manual Length = 496 Score = 113 bits (273), Expect = 4e-26 Identities = 77/276 (27%), Positives = 125/276 (45%), Gaps = 15/276 (5%) Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG--EQNVQREIQLLRILR 151 Y +G +G G++ V+ D + G + + EIQL ++ Sbjct: 10 YHIGREIGTGAFASVRLCYDDNAKIYAVKFVNKKHATSCMNAGVWARRMASEIQLHKLCN 69 Query: 152 -HKNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGL 209 HKN+I + N Q ++V+EF G L D +E G + A YF QL++G+ Sbjct: 70 GHKNIIHFYNTAENP--QWRWVVLEFAQGGDLFDKIEPDVG--IDEDVAQFYFAQLMEGI 125 Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269 ++H +GV H+D+KP N+LL + LKI+DFG A + + + GSP + PEI Sbjct: 126 SFMHSKGVAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLLNSPVGSPPYAAPEI 185 Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFE----GDNVYRLLEAISRXXXXXXXXXXX 325 +Q+ G+KVD+WS G+ L+ + G P++ Y L + Sbjct: 186 ---TQQYDGSKVDVWSCGIILFALLLGNTPWDEAISNTGDYLLYKKQCERPSYHPWNLLS 242 Query: 326 XXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQATPPF 361 ML DP R +V + +H W+ ++ PF Sbjct: 243 PGAYSIITGMLRSDPFKRYSVKHVVQHPWLTSSTPF 278 >SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 891 Score = 113 bits (271), Expect = 7e-26 Identities = 82/288 (28%), Positives = 127/288 (44%), Gaps = 25/288 (8%) Query: 85 KKKCKMVGKYVMGDVLGEGSYGKVK-----------------EMLDSQSLCRRAVXXXXX 127 +++ K++G YV+G +G GS GKVK + + + A Sbjct: 116 RERRKVIGNYVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEAT 175 Query: 128 XXXXXXPNGEQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLES 187 N E RE L +LRH + E DV + Y+V EF G Sbjct: 176 KAAQSEKNKEIRTVREAALSTLLRHPYICEARDVYITNSHY--YMVFEFVDGGQMLDYII 233 Query: 188 SPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALD 247 S GK ++QA + Q+ L YLH VVH+D+K N+L++ +KI DFG++ + Sbjct: 234 SHGK-LKEKQARKFVRQIGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLS---N 289 Query: 248 MFSQEDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYR 307 ++ ++ T GS F PE+ N A+ + G +VD+WS G+ LY + G+ PF+ N+ Sbjct: 290 LYRRQSRLRTFCGSLYFAAPELLN-AQPYIGPEVDVWSFGIVLYVLVCGKVPFDDQNM-S 347 Query: 308 LLEAISRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355 L A + ML DP R T+ E+ H W+ Sbjct: 348 ALHAKIKKGTVEYPSYLSSDCKGLLSRMLVTDPLKRATLEEVLNHPWM 395 >SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 110 bits (264), Expect = 5e-25 Identities = 73/267 (27%), Positives = 128/267 (47%), Gaps = 13/267 (4%) Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150 VG + +G LG G + + + + AV + + ++ E+ LLR++ Sbjct: 7 VGPWELGLSLGSGGPNSSR-LAKHRETGQLAVVKPIVGWSELTSSQQARIEGELVLLRLI 65 Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG--VLQDMLESSPGKKFPQRQAHDYFLQLLDG 208 H NV++L+DVI ++++++V+E+ G + ML F ++ + Q+L G Sbjct: 66 EHPNVLQLIDVI--SAQEQLFVVVEYMPGGELFDCMLRKG---SFTEQDTAKFLWQILCG 120 Query: 209 LDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPE 268 L+Y H + H+D+KP NL L ++KI +FG+A + + T GSP + PE Sbjct: 121 LEYCHKLHICHRDLKPENLYLDAHGSIKIGEFGMA---SIQQPGKLLQTSCGSPHYASPE 177 Query: 269 IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXX 328 I G + G DIWS G+ + + TG+ PF+ DN+ LL + + Sbjct: 178 IIMG-RSYDGCASDIWSCGIIFFALLTGKLPFDDDNIRSLLLKVCQ-GQFEMPSNISPQA 235 Query: 329 XXXXXHMLNRDPTLRPTVHEIRRHAWV 355 ML+ D + R T+ +IR H ++ Sbjct: 236 QHLLYRMLDVDSSTRITMEQIREHPFL 262 >SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Schizosaccharomyces pombe|chr 2|||Manual Length = 423 Score = 109 bits (262), Expect = 8e-25 Identities = 78/270 (28%), Positives = 136/270 (50%), Gaps = 13/270 (4%) Query: 89 KMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLR 148 + VG +++ +G GS GKVK +++ + + A+ VQRE L R Sbjct: 48 RQVGNWIIKKTIGAGSMGKVKLVVNILTGEKAALKMIPFTPNNTSQT--VRVQREALLGR 105 Query: 149 ILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGK-KFPQRQAHDYFLQLLD 207 +LRH N+ ++D I Y++ E+ G +LE + K + A + +QL++ Sbjct: 106 LLRHPNICRVIDCIRTPACT--YILFEYVPG--GQLLEYILARGKLDEDLARSFAMQLIN 161 Query: 208 GLDYLHGQGVVHKDIKPGNLLLTLD-QTLKITDFGVAEALDMFSQEDICYTGQGSPAFQP 266 L YLH +VH+D+K N+LLT D + +K+ DFG++ + +S++D+ T GS F Sbjct: 162 ALVYLHKNFIVHRDLKIENVLLTQDSRQVKLIDFGLS---NFYSKDDLLRTYCGSLYFAA 218 Query: 267 PEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXX 326 PE+ + A+ + G +VD+WS GV +Y M GR PF+ +V +L + + Sbjct: 219 PELLD-AKPYIGPEVDVWSLGVVIYVMVCGRVPFDDVSV-PMLHSKIKSGKLEFPSYISE 276 Query: 327 XXXXXXXHMLNRDPTLRPTVHEIRRHAWVQ 356 MLN +P R ++ + + W++ Sbjct: 277 DCCSLIAAMLNVNPRKRCSLEQAAKFPWLK 306 >SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizosaccharomyces pombe|chr 1|||Manual Length = 532 Score = 107 bits (256), Expect = 5e-24 Identities = 76/270 (28%), Positives = 120/270 (44%), Gaps = 10/270 (3%) Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150 VG +++G LG+G+ KVK Q+ + A+ ++ +QRE+ +LR L Sbjct: 20 VGPWLLGRTLGQGNLAKVKLGKHFQTNEKVALKMVYNDELEDKDTWKR-LQREVTILRQL 78 Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLD 210 H N+I L V + K + L +E+ L M+ + + F Q++ +D Sbjct: 79 HHPNIITLYQV-FRVPKYTV-LALEYMDTDLHSMVVKH--NRLDECTTRKIFRQIVHAID 134 Query: 211 YLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIA 270 Y H V H+D+K N+LL D +K+TDFG++ + T G+P + PE+ Sbjct: 135 YCHLHRVAHRDLKLENILLNKDLVVKLTDFGLS---NFMLDGSFLSTSCGTPHYAAPEVI 191 Query: 271 NGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXX 330 G + G VD+W G+ LY M G +PFE + +L + + Sbjct: 192 QG-RYYDGCDVDVWGCGILLYLMLVGEFPFEDVTISNVLSRVCK-GIYTIPSFVSSSASD 249 Query: 331 XXXHMLNRDPTLRPTVHEIRRHAWVQATPP 360 ML PT R V EI +H W A P Sbjct: 250 LIRQMLMVLPTSRIKVAEIMQHPWFIADLP 279 >SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosaccharomyces pombe|chr 1|||Manual Length = 636 Score = 105 bits (251), Expect = 2e-23 Identities = 85/281 (30%), Positives = 130/281 (46%), Gaps = 17/281 (6%) Query: 98 DVLGEGSYGKVK--EMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQR---EIQLLRILRH 152 +V+G G++G V+ +D Q+ + + ++ +R E + LRH Sbjct: 355 EVIGRGAFGVVRIAHKVDPQNSGSETLYAVKEFRRKPAESQKKYTKRLTSEFCISSSLRH 414 Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212 NVI +D+I D K VME C G L + G+ P +A +F QL+ G+DYL Sbjct: 415 PNVIHTLDLI-QDGKGDYCEVMELCSGGDLYTLIMAAGRLEPM-EADCFFKQLMRGVDYL 472 Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQ--GSPAFQPPEIA 270 H GV H+D+KP NLLLT+ +LKITDFG E M +++ T GS + PE Sbjct: 473 HDMGVAHRDLKPENLLLTVSGSLKITDFGNGECFRMAWEKEAHMTCGLCGSAPYIAPEEY 532 Query: 271 NGAEQFSGTKVDIWSSGVTLYNMTTGRYPF-----EGDNVYR--LLEAISRXXXXXXXXX 323 +E F VD+W+ GV M TGR+ + D Y L++ + Sbjct: 533 TESE-FDPRAVDVWACGVIYMAMRTGRHLWRVAKKSEDEYYSRYLMDRKNESGYEPIEML 591 Query: 324 XXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPG 364 ++L+ +PT R T +I + WV++ E G Sbjct: 592 ERSRCRNTLYNILHPNPTYRLTAKQIMKSEWVRSITLCEAG 632 >SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |Schizosaccharomyces pombe|chr 1|||Manual Length = 672 Score = 103 bits (248), Expect = 4e-23 Identities = 82/278 (29%), Positives = 125/278 (44%), Gaps = 15/278 (5%) Query: 78 DIIYRSRKKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGE 137 D+I + VG Y + V+GEGS+GKV L + L V Sbjct: 15 DLIATICNPRISDVGTYRIESVVGEGSFGKV--YLAAHLLTNTKVVLKSSCRKQAII--- 69 Query: 138 QNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQR 196 + REI R L H N+ L +V+ +++ +YL ME+C G L D + K+ ++ Sbjct: 70 --LAREIHHHRRLLHPNITRLYEVVCTEDR--IYLAMEYCPNGELYDWVARE--KRLDEK 123 Query: 197 QAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICY 256 QL + YLH QG VH+D+K N+ L +K+ DFG + D S+ Sbjct: 124 TTCRIMWQLCCAIQYLHRQGCVHRDLKLENIFLDKAYNVKLGDFGFSRDSDC-SRRTFMN 182 Query: 257 TGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXX 316 T G+ A+ PE+ G ++ G VDIWS G+ +Y + GR PF+ D+V L E Sbjct: 183 TRCGTVAYCAPELVQG-HKYIGECVDIWSLGIIMYALLIGRLPFDEDDV-SLTEQKIINE 240 Query: 317 XXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAW 354 +L +D LRP++ +I H + Sbjct: 241 CPQYPETLSKNSSSLLKSLLCKDYRLRPSIDQIISHPY 278 >SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc7|Schizosaccharomyces pombe|chr 2|||Manual Length = 1062 Score = 103 bits (247), Expect = 6e-23 Identities = 70/261 (26%), Positives = 118/261 (45%), Gaps = 13/261 (4%) Query: 96 MGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNV 155 +GD LG+G++G V L+ ++ V + ++ EI LL+ L H N+ Sbjct: 11 LGDCLGKGAFGAVYRGLNIKN--GETVAVKKVKLSKMLKSDLSVIKMEIDLLKNLDHPNI 68 Query: 156 IELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHG 214 ++ ++ + +++E+C G L+ + ++ K P+ Y Q+L GL YLH Sbjct: 69 VKYRGSYQTNDS--LCIILEYCENGSLRSICKNFG--KIPENLVALYTFQVLQGLLYLHN 124 Query: 215 QGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAE 274 QGV+H+DIK N+L T D T+K+ DFGVA ++ + GSP + PE+ Sbjct: 125 QGVIHRDIKGANILTTKDGTIKLADFGVATKINALEDHSVV----GSPYWMAPEVIELVG 180 Query: 275 QFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXXXXH 334 + T DIWS G T+ + G P+ + L + + Sbjct: 181 --ATTASDIWSVGCTVIELLDGNPPYYDLDPTSALFRMVKDEHPPLPSNISSAAKSFLMQ 238 Query: 335 MLNRDPTLRPTVHEIRRHAWV 355 +DP LR ++ +H WV Sbjct: 239 CFQKDPNLRIKTRKLLKHPWV 259 >SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1023 Score = 102 bits (245), Expect = 1e-22 Identities = 73/250 (29%), Positives = 123/250 (49%), Gaps = 25/250 (10%) Query: 75 DSADIIYRSRKKKCK--MVGKYVMGDVLGEGSYGKVK---EMLDSQSLCRRAVXXXXXXX 129 D+++ + R+ +K K G Y++G +G G +GKVK + + S R+ Sbjct: 471 DTSERLTRTLRKSTKNYTFGSYILGRTIGTGEFGKVKLGWPLPKANSTIHRSTPQVVIKI 530 Query: 130 XXXXPNGEQN--VQREIQLLRIL--RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDM 184 Q + RE+ +L+ L H ++++ +D + K +V+++ G L D Sbjct: 531 VLSTKQNCQTSRLMREVAILKGLGNNHPHIVKYLDFVKT--KHHFGIVLDYVNGGELFDY 588 Query: 185 LESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAE 244 + + ++ A F QL+ G+ YLH +GVVH+D+K N+LL ++ + I DFG A Sbjct: 589 ILAR--RRLEDSVACRLFAQLISGVAYLHSRGVVHRDLKLENILLDTNRNIVIADFGFAT 646 Query: 245 ALDMFS----------QEDICYTGQGSPAFQPPEIAN-GAEQFSGTKVDIWSSGVTLYNM 293 F+ + D+ T GSP + PE+ N + ++GT+ DIWS GV LY M Sbjct: 647 TFGHFNTLSEHSLPTEKPDLFSTSCGSPCYAAPELVNCKSGMYAGTQADIWSCGVILYAM 706 Query: 294 TTGRYPFEGD 303 G PF+ D Sbjct: 707 LAGYLPFDDD 716 >SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 101 bits (243), Expect = 2e-22 Identities = 70/216 (32%), Positives = 111/216 (51%), Gaps = 9/216 (4%) Query: 98 DVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIE 157 D +GEG+YGKV + +++ + V RE+++L+ LRHKN++ Sbjct: 281 DQIGEGTYGKVYKAINT--VTGDLVALKRIRLEQEKDGFPITTVREVKILQRLRHKNIVR 338 Query: 158 LVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGV 217 L++++ EK +Y+V E+ L +L +S P H Q+ + L YLH +GV Sbjct: 339 LLEIMV--EKSSVYMVFEYMDHDLTGVLLNSQLHFTPGNIKH-LSKQIFEALAYLHHRGV 395 Query: 218 VHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANGAEQF 276 +H+DIK N+LL + LK DFG+A S + YT + F+PPE+ G + Sbjct: 396 LHRDIKGSNILLNNNGDLKFADFGLARF--NTSSKSANYTNRVITLWFRPPELLLGETAY 453 Query: 277 SGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312 T VDIWS+G + + TG+ F+G + LE I Sbjct: 454 D-TAVDIWSAGCIVMELFTGKPFFQGRDEISQLEVI 488 >SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizosaccharomyces pombe|chr 1|||Manual Length = 1401 Score = 101 bits (241), Expect = 3e-22 Identities = 86/338 (25%), Positives = 144/338 (42%), Gaps = 27/338 (7%) Query: 41 DGSPELHSVTWLDDEQIEDLD-LNLEQTNLCFHRVDSA----DIIYRSR------KKKCK 89 D E S+ L E + +D L +E+ N R+ D ++R+R Sbjct: 973 DVEEEALSIQLLQKETMLRIDELEIERNNTLLERLAIGHVLDDSVFRNRDFIKLASSFSN 1032 Query: 90 MVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRI 149 + ++ G + G +G V ++ ++ AV + + E+ +L Sbjct: 1033 ITIRWQQGHFVRSGMFGDVYTGVNMETGDLLAVKEIKLQDSRTFRSTVDQIHNEMTVLER 1092 Query: 150 LRHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDG 208 L H NV+ V + ++K+Y+ MEFC G L D+L + G+ + Y +QLL+G Sbjct: 1093 LNHPNVVTYYGVEVH--REKVYIFMEFCQGGSLADLL--AHGRIEDENVLKVYVVQLLEG 1148 Query: 209 LDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTG--------QG 260 L Y+H Q ++H+DIKP N+LL +K +DFG A + + ++ Y G Sbjct: 1149 LAYIHSQHILHRDIKPANILLDHRGMIKYSDFGSALYVSPPTDPEVRYEDIQPELQHLAG 1208 Query: 261 SPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPF-EGDNVYRLL--EAISRXXX 317 +P + PEI G ++ +DIWS G + M TG P+ E DN + ++ A Sbjct: 1209 TPMYMAPEIILGTKKGDFGAMDIWSLGCVILEMMTGSTPWSEMDNEWAIMYHVAAMHTPS 1268 Query: 318 XXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355 RDP RP ++ H W+ Sbjct: 1269 IPQNEKISSLARDFIEQCFERDPEQRPRAVDLLTHPWI 1306 >SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|chr 1|||Manual Length = 683 Score = 101 bits (241), Expect = 3e-22 Identities = 64/261 (24%), Positives = 120/261 (45%), Gaps = 10/261 (3%) Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153 Y D +GEG + + + D+ A + + EI++ + + H Sbjct: 41 YTRYDCIGEGGFARCFRVKDNYGNIYAA--KVIAKRSLQNDKTKLKLFGEIKVHQSMSHP 98 Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212 N++ +D ++ +YL++E C L ++L K+ + + +Q+L L Y+ Sbjct: 99 NIVGFIDCF--EDSTNIYLILELCEHKSLMELLRKR--KQLTEPEVRYLMMQILGALKYM 154 Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANG 272 H + V+H+D+K GN++L +KI DFG+A L E+ T G+P + PEI Sbjct: 155 HKKRVIHRDLKLGNIMLDESNNVKIGDFGLAALL--MDDEERKMTICGTPNYIAPEILFN 212 Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI-SRXXXXXXXXXXXXXXXXX 331 +++ +VD+WS+GV +Y + G+ PF+ V + I + Sbjct: 213 SKEGHSFEVDLWSAGVVMYALLIGKPPFQDKEVKTIYRKIKANSYSFPSNVDISAEAKDL 272 Query: 332 XXHMLNRDPTLRPTVHEIRRH 352 +L DP++RP++ +I H Sbjct: 273 ISSLLTHDPSIRPSIDDIVDH 293 >SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosaccharomyces pombe|chr 3|||Manual Length = 460 Score = 99 bits (238), Expect = 7e-22 Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 17/294 (5%) Query: 100 LGEGSYGKVKEMLDSQS---LCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVI 156 LG G++ VK ++ S + + + QREI +L+ L H V+ Sbjct: 173 LGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKSLHHPGVV 232 Query: 157 ELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQ 215 + ++ ND++ +++VME+ G L D L ++ ++ QLL+ L +LH Q Sbjct: 233 QCHEIFENDDE--LFIVMEYVEGGDLMDFLIANGS--IDEQDCKPLLKQLLETLLHLHKQ 288 Query: 216 GVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAE- 274 GV H+DIKP N+L+T D LKI+DFG+A+ + T G+ + PE+ Sbjct: 289 GVTHRDIKPENILITNDFHLKISDFGLAKVI--HGTGTFLETFCGTMGYLAPEVLKSKNV 346 Query: 275 QFSG---TKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXX---XXXXXXXXXXXX 328 G KVDIWS G LY M T PF + + +E IS+ Sbjct: 347 NLDGGYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLENEISEEG 406 Query: 329 XXXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRSDELHTST 382 ML +P R + E +H W E + +++L++S+ Sbjct: 407 IDLINRMLEINPEKRISESEALQHPWFYTVSTHEHRTPPSSSEHEATEQLNSSS 460 >SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 658 Score = 97.9 bits (233), Expect = 3e-21 Identities = 65/223 (29%), Positives = 103/223 (46%), Gaps = 11/223 (4%) Query: 140 VQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAH 199 + EI +++ HKN++ +D + K ++++VME+ G + E + Q Sbjct: 428 IVNEILVMKSHHHKNIVNFIDTFFY--KSELWMVMEYMRG--GSLTEVVTNNTLSEGQIA 483 Query: 200 DYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQ 259 + L+GL +LH G+VH+DIK N+LL+L +K+TDFG +D S T Sbjct: 484 AICKETLEGLQHLHENGIVHRDIKSDNILLSLQGDIKLTDFGFCAQID--SNMTKRTTMV 541 Query: 260 GSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXX-- 317 G+P + PE+ E G KVD+WS G+ M G P+ +N R L I+ Sbjct: 542 GTPYWMAPEVVTRKEY--GFKVDVWSLGIMAIEMVEGEPPYLNENPLRALYLIATIGTPK 599 Query: 318 XXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV-QATP 359 L +P RP+ E+ RH ++ QA P Sbjct: 600 ISRPELLSSVFHDFLSKSLTVNPKQRPSSGELLRHPFLKQAVP 642 >SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schizosaccharomyces pombe|chr 2|||Manual Length = 398 Score = 95.5 bits (227), Expect = 1e-20 Identities = 70/235 (29%), Positives = 112/235 (47%), Gaps = 18/235 (7%) Query: 86 KKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG---EQNVQR 142 K C + Y + + + EGSYG V LD + A+ PNG R Sbjct: 66 KSCNSIDDYEILEKIEEGSYGIVYRGLDKSTNTLVALKKIKFD-----PNGIGFPITSLR 120 Query: 143 EIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYF 202 EI+ L +RH N++EL V+ + + +YLVMEF L+ +L++ P + F Q + Sbjct: 121 EIESLSSIRHDNIVELEKVVVGKDLKDVYLVMEFMEHDLKTLLDNMP-EDFLQSEVKTLM 179 Query: 203 LQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSP 262 LQLL ++H +H+D+KP NLL+ +K+ DFG+A + S+ T Sbjct: 180 LQLLAATAFMHHHWYLHRDLKPSNLLMNNTGEIKLADFGLARPV---SEPKSSLTRLVVT 236 Query: 263 A-FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEG----DNVYRLLEAI 312 ++ PE+ GA + G ++D+WS G M T F G D +Y++ + Sbjct: 237 LWYRAPELLLGAPSY-GKEIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLL 290 >SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosaccharomyces pombe|chr 3|||Manual Length = 592 Score = 95.1 bits (226), Expect = 2e-20 Identities = 78/278 (28%), Positives = 124/278 (44%), Gaps = 22/278 (7%) Query: 89 KMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLR 148 K V + G++LGEGSY V ++ + A+ E+ V E + L Sbjct: 94 KRVSDFKFGEILGEGSYSTVLTATENSTKREYAIKVLDKRHIIKEKK-EKYVNIEKEALC 152 Query: 149 IL-RHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLL 206 IL +H I+L + +Y V+ G L D + +F + A Y ++ Sbjct: 153 ILSKHPGFIKLFYTF--QDAHNLYFVLSLARNGELLDYINKLG--RFNEICAQYYAALIV 208 Query: 207 DGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDM---FSQEDICYTGQ---- 259 D +DY+HG+GV+H+D+KP N+LL + KITDFG A+ L+ +ED + + Sbjct: 209 DSIDYMHGRGVIHRDLKPENILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQAH 268 Query: 260 -----GSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314 G+ + PE+ +++ +GT DIW+ G L+ M G+ PF N Y ++I Sbjct: 269 SRSFVGTARYVSPEVL--SDKIAGTASDIWAFGCILFQMLAGKPPFVAGNEYLTFQSILH 326 Query: 315 XXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRH 352 +L DP R TV EI +H Sbjct: 327 -LSYEIPPDISDVASDLIKKLLVLDPKDRLTVDEIHQH 363 >SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 93.9 bits (223), Expect = 4e-20 Identities = 85/329 (25%), Positives = 140/329 (42%), Gaps = 22/329 (6%) Query: 85 KKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREI 144 K+ +G + +G LG GS V+ L + A P ++ EI Sbjct: 3 KRHKNTIGVWRLGKTLGTGSTSCVR-------LAKHA-KTGDLAAIKIIPIRYASIGMEI 54 Query: 145 QLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFL 203 ++R+LRH N++ L DV + D Q MYL +E+ G L + +R+A Y Sbjct: 55 LMMRLLRHPNILRLYDV-WTDH-QHMYLALEYVPDGELFHYIRKHG--PLSEREAAHYLS 110 Query: 204 QLLDGLDYLHGQGVVHKDIKPGNLLLTL-DQTLKITDFGVAEALDMFSQEDICYTGQ-GS 261 Q+LD + + H H+D+K N+L+ + +Q +KI DFG+A D C GS Sbjct: 111 QILDAVAHCHRFRFRHRDLKLENILIKVNEQQIKIADFGMATV----EPNDSCLENYCGS 166 Query: 262 PAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXX 321 + PEI + + + G D+WS GV LY++ + + PF G N + I R Sbjct: 167 LHYLAPEIVSH-KPYRGAPADVWSCGVILYSLLSNKLPFGGQNTDVIYNKI-RHGAYDLP 224 Query: 322 XXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRS-DELHT 380 ML+ +P+ R T+ E+ H ++ + P S DE+ Sbjct: 225 SSISSAAQDLLHRMLDVNPSTRITIPEVFSHPFLMGCTSLSSMDSTTPPTPSLSIDEIDP 284 Query: 381 STVIPYLVERHYASAQEYFTERDLRQESD 409 V V +S+++ R ++D Sbjct: 285 LVVDCMCVLWKKSSSKKVVRRLQQRDDND 313 >SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|Schizosaccharomyces pombe|chr 3|||Manual Length = 288 Score = 93.5 bits (222), Expect = 6e-20 Identities = 63/210 (30%), Positives = 102/210 (48%), Gaps = 17/210 (8%) Query: 100 LGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIELV 159 LGEG+Y V + Q+ + REI L++ LRH N++ L Sbjct: 9 LGEGTYAHVYK---GQNRVTGEIVALKVIRIDADEGTPSTAIREISLMKELRHPNIMSLS 65 Query: 160 DVIYNDEKQKMYLVMEFCVGVLQDMLESSPGK-KFPQRQAHDYFLQLLDGLDYLHGQGVV 218 DV+ + K + LV E+ L+ +++ + P Q ++ QLL G+ + H V+ Sbjct: 66 DVLQTENK--LMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCHENRVL 123 Query: 219 HKDIKPGNLLLTLDQTLKITDFGVAEAL----DMFSQEDICYTGQGSPAFQPPEIANGAE 274 H+D+KP NLL+ LK+ DFG+A ++ + FS E + ++ P++ G+ Sbjct: 124 HRDLKPQNLLINSRGELKLADFGLARSIGIPVNTFSNEVVTLW------YRAPDVLLGSR 177 Query: 275 QFSGTKVDIWSSGVTLYNMTTGRYPFEGDN 304 +S T +DIWS G + M TGR F G N Sbjct: 178 VYS-TSIDIWSVGCIMAEMATGRPLFAGSN 206 >SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1|||Manual Length = 1116 Score = 93.1 bits (221), Expect = 8e-20 Identities = 58/223 (26%), Positives = 106/223 (47%), Gaps = 9/223 (4%) Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGE------QNVQREIQL 146 K++ G+++G G+YGKV ++ + AV + + ++ EI + Sbjct: 824 KWMKGELIGNGTYGKVFLAMNINTGELIAVKQVEIPQTINGRHDQLRKDIVDSINAEISM 883 Query: 147 LRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLL 206 + L H N+++ + + + + + +E+ G + G F ++ Q+L Sbjct: 884 IADLDHLNIVQYLG--FEKTETDISIFLEYVSGGSIGRCLRNYGP-FEEQLVRFVSRQVL 940 Query: 207 DGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQP 266 GL YLH +G++H+D+K NLL+ D KI+DFG+++ D D + QGS + Sbjct: 941 YGLSYLHSKGIIHRDLKADNLLIDFDGVCKISDFGISKHSDNVYDNDANLSMQGSIFWMA 1000 Query: 267 PEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLL 309 PE+ + Q KVD+WS G + M GR P+ D + + Sbjct: 1001 PEVIHNDHQGYSAKVDVWSLGCVVLEMLAGRRPWSTDEAIQAM 1043 >SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schizosaccharomyces pombe|chr 1|||Manual Length = 387 Score = 92.7 bits (220), Expect = 1e-19 Identities = 67/227 (29%), Positives = 115/227 (50%), Gaps = 20/227 (8%) Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153 Y V+G GS+G V ++ +S + A+ ++ RE+Q++RI++H Sbjct: 32 YTSSKVVGSGSFGVVMQVHLIESDSKAAIKRVL--------QDKRFKNRELQIMRIMKHP 83 Query: 154 NVIELVDVIYN--DEKQKMYL--VMEFCVGVLQ--DMLESSPGKKFPQRQAHDYFLQLLD 207 N+++L+ Y D ++YL V+EF + L + P + Y QLL Sbjct: 84 NIVDLIAYYYTTGDNSDEVYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQLLR 143 Query: 208 GLDYLHGQGVVHKDIKPGNLLLTLDQ-TLKITDFGVAEALDMFSQEDICYTGQGSPAFQP 266 L Y+H G+ H+DIKP NLLL + LK+ DFG A+ L + + ++ Y S ++ Sbjct: 144 SLAYIHASGICHRDIKPQNLLLDPENGILKLCDFGSAKIL-VAGEPNVSYI--CSRYYRA 200 Query: 267 PEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDN-VYRLLEAI 312 PE+ GA ++ +DIWS+G + + G F G++ + +L+E I Sbjct: 201 PELIFGATDYTHA-IDIWSTGCVMAELMLGHPLFPGESGIDQLVEII 246 >SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2|Schizosaccharomyces pombe|chr 2|||Manual Length = 659 Score = 91.5 bits (217), Expect = 2e-19 Identities = 70/271 (25%), Positives = 119/271 (43%), Gaps = 13/271 (4%) Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNV----QREIQLLR 148 K++ G ++G GS+G+V +++ S AV + + EI LL+ Sbjct: 393 KWIRGALIGSGSFGQVYLGMNASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQ 452 Query: 149 ILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDG 208 L H+++++ + N + ++L E+ G L + G F + ++ Q L G Sbjct: 453 ELSHEHIVQYLGSNLNSDHLNIFL--EYVPGGSVAGLLTMYGS-FEETLVKNFIKQTLKG 509 Query: 209 LDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPE 268 L+YLH +G+VH+DIK N+L+ +KI+DFG+++ L++ S TG P+FQ Sbjct: 510 LEYLHSRGIVHRDIKGANILVDNKGKIKISDFGISKKLELNSTS--TKTGGARPSFQGSS 567 Query: 269 IANGAEQFSGT----KVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXX 324 E T K DIWS G + M T ++P+ + + + I Sbjct: 568 FWMAPEVVKQTMHTEKTDIWSLGCLVIEMLTSKHPYPNCDQMQAIFRIGENILPEFPSNI 627 Query: 325 XXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355 D LRPT E+ H +V Sbjct: 628 SSSAIDFLEKTFAIDCNLRPTASELLSHPFV 658 >SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharomyces pombe|chr 2|||Manual Length = 1016 Score = 91.5 bits (217), Expect = 2e-19 Identities = 64/238 (26%), Positives = 115/238 (48%), Gaps = 12/238 (5%) Query: 79 IIYRSRKKKCKMVG--KYVMGDVLGEGSYGKVK--EMLDSQSLCRRAVXXXXXXXXXXXP 134 ++ + K K +G + VLG+G++GKV E+ + L V Sbjct: 666 VVAQDLTHKAKRIGLEDFTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDEV 725 Query: 135 NGEQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFP 194 ++ +R + RH ++ L + + +Y VM+F G D++ ++F Sbjct: 726 ESTKSEKRVFLVANRERHPFLVNLHSCFQTETR--IYFVMDFVSG--GDLMLHIQQEQFS 781 Query: 195 QRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDI 254 +R+A Y ++ L Y H G++++D+K N+LL+ D +K+ D+G+ + DM+ ++ Sbjct: 782 RRRAQFYAAEVCLALKYFHDNGIIYRDLKLDNILLSPDGHVKVADYGLCKE-DMW-HDNT 839 Query: 255 CYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312 T G+P F PEI EQ VD W+ GV +Y M G+ PF G++ + +AI Sbjct: 840 TATFCGTPEFMAPEIL--LEQQYTRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFDAI 895 >SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces pombe|chr 1|||Manual Length = 312 Score = 91.5 bits (217), Expect = 2e-19 Identities = 66/264 (25%), Positives = 120/264 (45%), Gaps = 13/264 (4%) Query: 99 VLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIEL 158 ++G+GS+G V D +S + + + + +EI L L ++ + Sbjct: 11 LIGQGSFGSVFRAQDVES---SKIVALKVVDLDATKDQIETLTQEINFLIDLNSVHITKY 67 Query: 159 VDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGV 217 + + +++ ME+C G D+L+ S F +R + Q+L+ L YLHGQG Sbjct: 68 YASFVDGFR--LWITMEYCDGGSCLDLLKLSG--TFSERVIAEVMRQVLEALVYLHGQGK 123 Query: 218 VHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAEQFS 277 +H+DIK N+L D +K+ DFGV+ L+ ++ + G+P + PE+ + Sbjct: 124 MHRDIKAANILTMKDGLVKLADFGVSGQLESLRDKNDDFV--GTPFWMAPEVVK--QTGY 179 Query: 278 GTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXX-XXXXXXXXXXXXXXXXXHML 336 K DIWS G+T Y + TG P+ G + ++L I + + L Sbjct: 180 NYKADIWSLGITAYELATGEPPYSGIHPMKVLLLIPKHSPPSLERSKFSRAFCDFVSNCL 239 Query: 337 NRDPTLRPTVHEIRRHAWVQATPP 360 ++P R T + +H +++ P Sbjct: 240 KKNPKDRATAEYLSKHKFIKKYCP 263 >SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating kinase Crk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 335 Score = 90.6 bits (215), Expect = 4e-19 Identities = 63/194 (32%), Positives = 96/194 (49%), Gaps = 9/194 (4%) Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153 YV +GEG+Y V L Q R V + + REI+ LR RH Sbjct: 11 YVKERKVGEGTYAVV--FLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLRESRHD 68 Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213 NVIELVDV K + +++EF L+ ML F + + LL GL ++H Sbjct: 69 NVIELVDVF--STKSNLNIILEFLDSDLE-MLIKDKFIVFQPAHIKSWMVMLLRGLHHIH 125 Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGA 273 + ++H+D+KP NLL++ D LK+ DFG++ D + + + + ++PPE+ G Sbjct: 126 SRFILHRDLKPNNLLISSDGVLKLADFGLSR--DFGTPSHMSHQ-VITRWYRPPELFMGC 182 Query: 274 EQFSGTKVDIWSSG 287 + GT VD+WS G Sbjct: 183 RSY-GTGVDMWSVG 195 >SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 589 Score = 90.2 bits (214), Expect = 6e-19 Identities = 64/235 (27%), Positives = 107/235 (45%), Gaps = 11/235 (4%) Query: 140 VQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLESSPGKKFPQRQA 198 + EI ++R H N++ +D E+ +++VME+ G L D++E S K + Q Sbjct: 356 ILNEITVMRESIHPNIVTYLDSFLVRERH-LWVVMEYMNAGSLTDIIEKS---KLTEAQI 411 Query: 199 HDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTG 258 L+ G+ +LH + ++H+DIK N+LL +KITDFG L + + + T Sbjct: 412 ARICLETCKGIQHLHARNIIHRDIKSDNVLLDNSGNIKITDFGFCARLSNRTNKRV--TM 469 Query: 259 QGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXX 318 G+P + PE+ E GTKVDIWS G+ + M P+ ++ R L I++ Sbjct: 470 VGTPYWMAPEVVKQNEY--GTKVDIWSLGIMIIEMIENEPPYLREDPIRALYLIAKNGTP 527 Query: 319 XXX--XXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPR 371 L D R T E+ H+++ P E + ++ R Sbjct: 528 TLKKPNLVSKNLKSFLNSCLTIDTIFRATAAELLTHSFLNQACPTEDLKSIIFSR 582 >SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 372 Score = 89.4 bits (212), Expect = 1e-18 Identities = 66/224 (29%), Positives = 106/224 (47%), Gaps = 11/224 (4%) Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152 +Y M +++G+G+YG V L S + AV P REI+LLR RH Sbjct: 38 EYEMINLIGQGAYGVVCAALHKPSGLKVAVKKIHPFNH---PVFCLRTLREIKLLRHFRH 94 Query: 153 KNVIELVDVI---YNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209 +N+I ++D++ E + +Y+V E L ++ S P + Q+L L Sbjct: 95 ENIISILDILPPPSYQELEDVYIVQELMETDLYRVIRSQP---LSDDHCQYFTYQILRAL 151 Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQ-GSPAFQPPE 268 +H GVVH+D+KP NLLL + LK+ DFG+A + T + ++ PE Sbjct: 152 KAMHSAGVVHRDLKPSNLLLNANCDLKVADFGLARSTTAQGGNPGFMTEYVATRWYRAPE 211 Query: 269 IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312 I ++S +D+WS+G L M + R F G + + + I Sbjct: 212 IMLSFREYS-KAIDLWSTGCILAEMLSARPLFPGKDYHSQITLI 254 >SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyces pombe|chr 1|||Manual Length = 349 Score = 88.6 bits (210), Expect = 2e-18 Identities = 68/205 (33%), Positives = 102/205 (49%), Gaps = 16/205 (7%) Query: 100 LGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIELV 159 +G G++G V D L V P + RE++LL+ LRH+N+I L Sbjct: 26 IGMGAFGLVCSAKDQ--LTGMNVAVKKIMKPFSTPVLAKRTYRELKLLKHLRHENIISLS 83 Query: 160 DVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFL-QLLDGLDYLHGQGVV 218 D I+ + +Y V E L +L S P + Q YFL Q+L GL ++H GV+ Sbjct: 84 D-IFISPFEDIYFVTELLGTDLHRLLTSRP----LETQFIQYFLYQILRGLKFVHSAGVI 138 Query: 219 HKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANGAEQFS 277 H+D+KP N+L+ + LKI DFG+A +D TG S ++ PEI ++++ Sbjct: 139 HRDLKPSNILINENCDLKICDFGLARI------QDPQMTGYVSTRYYRAPEIMLTWQKYN 192 Query: 278 GTKVDIWSSGVTLYNMTTGRYPFEG 302 +VDIWS+G M G+ F G Sbjct: 193 -VEVDIWSAGCIFAEMIEGKPLFPG 216 >SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizosaccharomyces pombe|chr 2|||Manual Length = 381 Score = 87.8 bits (208), Expect = 3e-18 Identities = 59/179 (32%), Positives = 95/179 (53%), Gaps = 12/179 (6%) Query: 142 REIQLLRILRHKNVIELVDVIYNDEKQK----MYLVMEFCVGVLQDMLE--SSPGKKFPQ 195 RE+Q++R + H N+I+L+ + K + L++E+ + D + + K P Sbjct: 65 RELQIMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSIPN 124 Query: 196 RQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQ-TLKITDFGVAEALDMFSQEDI 254 Y QL L YLH GV H+DIKP NLL+ LK+ DFG A+ L + S+ ++ Sbjct: 125 LSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVL-VPSEPNV 183 Query: 255 CYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGD-NVYRLLEAI 312 Y S ++ PE+ GA ++ TK+D+WS+ + + GR F GD +V +L+E I Sbjct: 184 SYI--CSRYYRAPELVFGATHYT-TKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEII 239 >SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizosaccharomyces pombe|chr 2|||Manual Length = 591 Score = 87.4 bits (207), Expect = 4e-18 Identities = 73/255 (28%), Positives = 124/255 (48%), Gaps = 23/255 (9%) Query: 78 DIIYRSRKKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGE 137 D++ + C + Y + + LGEG++G+V + SQ V G Sbjct: 20 DVVPKLHFVGCSHLTDYHLMEKLGEGTFGEVYK---SQRRKDGKVYALKRILMHTEKEGF 76 Query: 138 Q-NVQREIQLLRILRHKNVIELVD--VIYNDEKQK----MYLVMEFCVGVLQDMLESSPG 190 REI++L+ ++H+N+I L D V+ D+K + +Y+V + L +LE+ P Sbjct: 77 PITAIREIKILKSIKHENIIPLSDMTVVRADKKHRRRGSIYMVTPYMDHDLSGLLEN-PS 135 Query: 191 KKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEAL--DM 248 KF + Q Y QL G YLH Q ++H+D+K NLL+ LKI DFG+A + + Sbjct: 136 VKFTEPQIKCYMKQLFAGTKYLHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEES 195 Query: 249 FSQEDIC--------YTG-QGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYP 299 ++ ++ YTG + ++ PE+ G +++ T +D+WS G + M GR Sbjct: 196 YANKNPGLPPPNRREYTGCVVTRWYRSPELLLGERRYT-TAIDMWSVGCIMAEMYKGRPI 254 Query: 300 FEGDNVYRLLEAISR 314 +G + L+ I R Sbjct: 255 LQGSSDLDQLDKIFR 269 >SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosaccharomyces pombe|chr 1|||Manual Length = 722 Score = 87.0 bits (206), Expect = 5e-18 Identities = 72/287 (25%), Positives = 128/287 (44%), Gaps = 40/287 (13%) Query: 93 KYVMGDVLGEGSYG---KVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRI 149 KY + + +G GS+G KV+ + D L ++ + +Q + E+ +LR Sbjct: 3 KYKILECIGHGSFGRIYKVQRLKDGALLAQKEIHFGNITRQE-----KQYIADEVNILRN 57 Query: 150 LRHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLE--SSPGKKFPQRQAHDYFLQLL 206 L+H N+++ N Q + L ME+C G L ++++ K+F +++ +F QLL Sbjct: 58 LKHPNIVQYCGEELNRSAQVINLYMEYCGHGDLANLIQRYKEEKKRFTEQEVLKFFTQLL 117 Query: 207 DGLDYLH-------------------GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALD 247 L H Q V+H+DIKP N+ L + ++K+ DFG+++ LD Sbjct: 118 LALYRCHYGENAPACDSQWPREIFHPKQSVLHRDIKPANIFLDENNSVKLGDFGLSKLLD 177 Query: 248 ---MFSQEDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDN 304 +F+Q + G+P + PEI + K D+W+ G ++ + +PFEG + Sbjct: 178 NTRVFTQSYV-----GTPYYMSPEIIRSSPY--SAKSDVWALGCVIFEICMLTHPFEGRS 230 Query: 305 VYRLLEAISRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRR 351 L I + H L + LRPT +++ R Sbjct: 231 YLELQRNICQGNLSCWDHHYSDDVFLLIRHCLEVNSDLRPTTYQLLR 277 >SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosaccharomyces pombe|chr 3|||Manual Length = 436 Score = 85.8 bits (203), Expect = 1e-17 Identities = 59/216 (27%), Positives = 104/216 (48%), Gaps = 8/216 (3%) Query: 99 VLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIEL 158 VLG GSYGKV + + A G + + E Q+L +RH + L Sbjct: 96 VLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKGLEQTKNERQILEEVRHPFICRL 155 Query: 159 VDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVV 218 + ++ +YL++++ G + + + P+ Y +L L +LH G+V Sbjct: 156 YYAFQDHDR--LYLILQYAPGG-ELFSHLAEQRMLPEDVVAFYTAELTLALIHLHKLGIV 212 Query: 219 HKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAEQFSG 278 ++D+KP N LL + + +TDFG+++ + + C + G+ + PEI EQ Sbjct: 213 YRDLKPENCLLDAEGHILLTDFGLSKVAENGAD---CRSFVGTEEYCAPEIL--LEQPYD 267 Query: 279 TKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314 VD WS G+ ++++ TG PF +N R++E I+R Sbjct: 268 HAVDWWSMGILIFDLLTGSPPFTANNHKRIMEKITR 303 >SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase Ppk21|Schizosaccharomyces pombe|chr 2|||Manual Length = 550 Score = 85.0 bits (201), Expect = 2e-17 Identities = 59/231 (25%), Positives = 104/231 (45%), Gaps = 14/231 (6%) Query: 89 KMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQ-NVQREIQLL 147 K YV GD++G+GS+ KV+ D +S A+ + N++R+ ++ Sbjct: 49 KSPADYVFGDIIGDGSFSKVRRATDKKSWKEYAIKVLDKKYIVKENKVKYVNIERD-SMM 107 Query: 148 RILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKF-PQRQAHDYFLQLL 206 R+ + L +D K+Y V+E ++L+ +F + Y ++L Sbjct: 108 RLNGFPGISRLFHTFQDD--LKLYYVLELAPN--GELLQYIKKYRFLDENCVRFYAAEIL 163 Query: 207 DGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTG-----QGS 261 ++Y+H G++H+D+KP N+L + +KITDFG A+ L YT G+ Sbjct: 164 SSIEYMHSCGIIHRDLKPENILFDGNMHVKITDFGTAKILPPKYVNSPDYTTFPSSFVGT 223 Query: 262 PAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312 + PE+ + Q D+W+ +Y M G PF G N + + I Sbjct: 224 AEYVAPELL--SRQVVSKSSDLWAFACVVYQMIVGSPPFHGSNPNNIFKKI 272 >SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 474 Score = 84.6 bits (200), Expect = 3e-17 Identities = 58/173 (33%), Positives = 94/173 (54%), Gaps = 22/173 (12%) Query: 142 REIQLLRIL---RHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLESS--PGKKFPQ 195 +E+ +LR L RH+N+I V+ ++ Y+V+E+C +G L + + ++ P K Sbjct: 54 QEVNILRQLSRSRHRNIIHFVESF--EDNVYYYVVLEYCPLGDLYECILNNDFPNAKNQP 111 Query: 196 RQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQ-----TLKITDFGVAEALDMFS 250 + FLQ++DG+ +LH G+ H+D+KP N LL+L + +KI+DFG+A D S Sbjct: 112 EMIKNIFLQIIDGVAHLHSHGIYHRDLKPENFLLSLSEDGSELVVKISDFGLA-CRDKIS 170 Query: 251 QEDICYTGQGSPAFQPP---EIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPF 300 + G GS + P E +GA +S DIW+ G+ L N+ R PF Sbjct: 171 YD----FGTGSDRYMAPEQFEEVDGA-GYSPRAADIWALGICLLNLIFARNPF 218 >SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosaccharomyces pombe|chr 2|||Manual Length = 652 Score = 84.6 bits (200), Expect = 3e-17 Identities = 54/224 (24%), Positives = 113/224 (50%), Gaps = 15/224 (6%) Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153 Y +++G GSYG V + + L + V ++Q+E+ +L L+ Sbjct: 10 YTKLELVGRGSYGAVYRGICN--LTKETVAIKILNLDTDEDE-VSDIQKEVAVLSELKQS 66 Query: 154 NVIELVDVIYNDEK---QKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209 +V ++ Y+ ++++M++C G ++ ++E+ P + + L L Sbjct: 67 DVENIIK--YHGSYLVGTNLWIIMDYCHGGSVRTLMEAGP---ISEPCISLILRETLQAL 121 Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269 ++H G++H+DIK N+L+++ +K+ DFGVA L++ ++ I + G+P + PE+ Sbjct: 122 KFIHHAGIIHRDIKAANILVSMSGNVKLCDFGVAAELNINRRKRITFI--GTPYWMAPEV 179 Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAIS 313 ++++ DIWS G+T Y + TG P ++ +R + I+ Sbjct: 180 IRDGQEYN-VMADIWSLGITAYEIATGSPPHAKEDPFRAVYLIA 222 >SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosaccharomyces pombe|chr 1|||Manual Length = 988 Score = 84.2 bits (199), Expect = 4e-17 Identities = 59/233 (25%), Positives = 112/233 (48%), Gaps = 10/233 (4%) Query: 82 RSRKKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGE-QNV 140 R KK + + VLG+G++GKV ML + ++ N E +++ Sbjct: 652 RREKKNRVTLDDFTFLAVLGKGNFGKV--MLAEYKVNKKFYAIKVLKKEAILKNEELESL 709 Query: 141 QREIQLLRILRHKNVIELVDVIYNDEKQ-KMYLVMEFCVGVLQDMLESSPGKKFPQRQAH 199 + E + + + L+++ + + ++Y VME+ +G D++ ++F ++A Sbjct: 710 KTEKHVFEVANKEKHPFLLNLFASFQTSTRVYFVMEYILG--GDLMVHIQRQQFSVKRAR 767 Query: 200 DYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQ 259 Y ++ L Y H G+ ++D+K N+LL D ++I D+G+ + + + Sbjct: 768 FYGAEVCLALKYFHENGIAYRDLKLDNILLCPDGHIRIADYGLCKENMLLGNTTSTFC-- 825 Query: 260 GSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312 G+P F PEI EQ VD W+ GV +Y M G+ PF+G++ + +AI Sbjct: 826 GTPEFMAPEIL--LEQQYSKDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAI 876 >SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 83.8 bits (198), Expect = 5e-17 Identities = 71/227 (31%), Positives = 103/227 (45%), Gaps = 15/227 (6%) Query: 89 KMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG-EQNVQREIQLL 147 K GK+ G +LG G+ G V+ M S AV + V E + Sbjct: 299 KKYGKF--GRMLGSGAGGSVRIMKRSSDGKIFAVKEFRARRPTETEREYARKVTAEFCIG 356 Query: 148 RILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLD 207 L H N+IE +D++ +E +K Y VME+ DM K + + F QLL Sbjct: 357 SALHHTNIIETLDIV--EENKKFYEVMEYAP---YDMFSIVMSGKMTMPEVYCCFKQLLS 411 Query: 208 GLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDIC-YTG-QGSPAFQ 265 G+ YLH G+ H+D+K NL++ + +KI DFG A + DI TG GS + Sbjct: 412 GVAYLHSMGLAHRDLKLDNLVVDSNCFVKIIDFGSAVVFKYPFEADIVEATGVVGSDPYL 471 Query: 266 PPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFE----GDNVYRL 308 PE + + VDIWSS + M R+P++ DN +RL Sbjct: 472 APETL-VRKLYDPRAVDIWSSAIIFCCMALRRFPWKYPKLSDNSFRL 517 >SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 363 Score = 83.8 bits (198), Expect = 5e-17 Identities = 66/234 (28%), Positives = 107/234 (45%), Gaps = 20/234 (8%) Query: 137 EQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLES--SPGKKF 193 ++ + RE+++ R +++ YN+ + ++ + ME+C G L + + S G + Sbjct: 119 QKQLLRELKINRSCTSPYIVKYYGACYNNAECQLNIAMEYCGAGSLDAIYKRVRSQGGRT 178 Query: 194 PQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQED 253 +R +L GL YLH + ++H+DIKP N+LLT +K+ DFGV+ L Sbjct: 179 GERPLGKIAFGVLSGLSYLHDRKIIHRDIKPSNILLTSKGQVKLCDFGVSGEL----VNS 234 Query: 254 ICYTGQGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPF--EGD---NVYR 307 + T G+ + PE I+ G+ S DIWS G+TL + R+PF EG Sbjct: 235 LAGTFTGTSYYMAPERISGGSYTISS---DIWSLGLTLMEVALNRFPFPPEGSPPPMPIE 291 Query: 308 LLEAISRXXXXXXXXXXXXXXXXXXXHM----LNRDPTLRPTVHEIRRHAWVQA 357 LL I H L++D T RP ++ H WV+A Sbjct: 292 LLSYIINMPPPLLPQEPGIKWSKSFQHFLCVCLDKDKTRRPGPQKMLTHPWVKA 345 >SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 422 Score = 83.4 bits (197), Expect = 6e-17 Identities = 66/241 (27%), Positives = 112/241 (46%), Gaps = 9/241 (3%) Query: 74 VDSADIIYRSRKKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXX 133 +D +YR ++ + + + LG+G+YG V + S + AV Sbjct: 1 MDRRHRVYRVFNQEMYVEPNFKVVKELGQGAYGIVCAARNVASKDQEAVAIKKITNVFSK 60 Query: 134 PNGEQNVQREIQLLRILR-HKNV--IELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPG 190 + REI+LL R H+N+ I +D+I ++Y+ E L +++S G Sbjct: 61 SILTKRALREIKLLIHFRNHRNITCIYDLDIINPYNFNEVYIYEELMEADLNAIIKS--G 118 Query: 191 KKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFS 250 + + Q+L GL Y+H V+H+D+KPGNLL+ D LKI DFG+A Sbjct: 119 QPLTDAHFQSFIYQILCGLKYIHSANVIHRDLKPGNLLVNADCELKICDFGLARGCSENP 178 Query: 251 QEDICYTGQ--GSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEG-DNVYR 307 +E+ + + + ++ PEI + +D+WS G L + G F+G D V++ Sbjct: 179 EENPGFMTEYVATRWYRAPEIMLSFSSYH-KGIDVWSVGCILAELLGGTPLFKGKDFVHQ 237 Query: 308 L 308 L Sbjct: 238 L 238 >SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalytic subunit Pka1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 512 Score = 82.2 bits (194), Expect = 1e-16 Identities = 69/245 (28%), Positives = 110/245 (44%), Gaps = 13/245 (5%) Query: 100 LGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIELV 159 LG GS+G+V + + + A+ E L R+ +H I ++ Sbjct: 207 LGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTCDERYILSRV-QHP-FITIL 264 Query: 160 DVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVV 218 + D K +++VM+F G L +L +FP++ A Y +++ LDYLH +V Sbjct: 265 WGTFQDAKN-LFMVMDFAEGGELFSLLRKC--HRFPEKVAKFYAAEVILALDYLHHNQIV 321 Query: 219 HKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAEQFSG 278 ++D+KP NLLL LKI DFG A+ + + C T G+P + PEI + + ++ Sbjct: 322 YRDLKPENLLLDRFGHLKIVDFGFAKRVSTSN----CCTLCGTPDYLAPEIIS-LKPYN- 375 Query: 279 TKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXXXXHMLNR 338 D WS G+ ++ M G PF +N +L E I H+L R Sbjct: 376 KAADWWSLGILIFEMLAGYPPFYSENPMKLYENILE-GKVNYPSYFSPASIDLLSHLLQR 434 Query: 339 DPTLR 343 D T R Sbjct: 435 DITCR 439 >SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase Cmk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 335 Score = 81.8 bits (193), Expect = 2e-16 Identities = 63/226 (27%), Positives = 104/226 (46%), Gaps = 16/226 (7%) Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL-- 150 KY +G VLG G+Y V+E + ++ + + V+ EI +L+ + Sbjct: 30 KYRVGRVLGGGTYATVREAVHIET---NKMYAAKIMNKKMMEKKQDFVKNEIAILKRVSY 86 Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGK-KFPQRQAHDYFLQLLDGL 209 H N++ LVD + + +YL+ E G ++ + K F + A + Sbjct: 87 EHPNILHLVD--FFETVNNLYLITELATG--GELFDRICAKGSFYEADAAALMRTTTSAV 142 Query: 210 DYLHGQGVVHKDIKPGNLLLTL---DQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQP 266 YLH G+VH+D+KP NLL + L I DFG++ + SQ + T G+P + Sbjct: 143 KYLHDNGIVHRDLKPENLLYRSKDPNSDLLIADFGLSHFYE-DSQYYMLMTACGTPEYMA 201 Query: 267 PEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312 PE+ G VD+W+ GV Y + +G PF + ++EAI Sbjct: 202 PEVFRRTGY--GKPVDMWAIGVITYFLLSGYTPFARPSQVEVIEAI 245 >SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Schizosaccharomyces pombe|chr 2|||Manual Length = 297 Score = 81.4 bits (192), Expect = 3e-16 Identities = 61/219 (27%), Positives = 104/219 (47%), Gaps = 16/219 (7%) Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153 Y + +GEG+YG V + L R V REI LL+ + + Sbjct: 4 YQKVEKIGEGTYGVVYKA--RHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVNDE 61 Query: 154 N----VIELVDVIYNDEKQKMYLVMEFCVGVLQ---DMLESSPGKKFPQRQAHDYFLQLL 206 N + L+D+++ + K +YLV EF L+ D + + R + QL+ Sbjct: 62 NNRSNCVRLLDILHAESK--LYLVFEFLDMDLKKYMDRISETGATSLDPRLVQKFTYQLV 119 Query: 207 DGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQ-GSPAFQ 265 +G+++ H + ++H+D+KP NLL+ + LK+ DFG+A + + + YT + + ++ Sbjct: 120 NGVNFCHSRRIIHRDLKPQNLLIDKEGNLKLADFGLARSFGVPLRN---YTHEIVTLWYR 176 Query: 266 PPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDN 304 PE+ G+ +S T VDIWS G M F GD+ Sbjct: 177 APEVLLGSRHYS-TGVDIWSVGCIFAEMIRRSPLFPGDS 214 >SPCC63.08c |ppk36|atg1|serine/threonine protein kinase Ppk36|Schizosaccharomyces pombe|chr 3|||Manual Length = 830 Score = 79.8 bits (188), Expect = 8e-16 Identities = 75/263 (28%), Positives = 118/263 (44%), Gaps = 49/263 (18%) Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150 +G YV+ +G GS+ V + +++ R + +N++ EI +L+ + Sbjct: 11 IGPYVIRSEIGRGSFAIVYKGKHTET--NRVISIKSVLTKKLTKKLLENLESEISILKEI 68 Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFC-VGVL------QDMLESSPGKKF------PQRQ 197 RH +V+EL+D I + ++LVME+C +G L ++ S P + P + Sbjct: 69 RHVHVVELIDCI--KAGRFIHLVMEYCSLGDLSYFIRKREKFNSIPSLAWINIDHPPVYK 126 Query: 198 A-------HDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQT---------------- 234 A + QL L +L + ++H+D+KP NLLL T Sbjct: 127 AGLNETLVRHFTQQLASALQFLRSRSLIHRDVKPQNLLLQPPPTAAYLEEHPQFVGSPKL 186 Query: 235 --LKITDFGVAEALDMFSQ-EDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLY 291 LK+ DFG A L S E +C GSP + PEI E++ K D+WS G LY Sbjct: 187 PMLKLADFGFARYLQTSSMAETLC----GSPLYMAPEILR-YEKYDA-KADLWSVGAVLY 240 Query: 292 NMTTGRYPFEGDNVYRLLEAISR 314 M G+ PF+ N LL I + Sbjct: 241 EMAVGKPPFKAPNHVELLRRIQK 263 >SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizosaccharomyces pombe|chr 1|||Manual Length = 646 Score = 78.2 bits (184), Expect = 2e-15 Identities = 53/178 (29%), Positives = 81/178 (45%), Gaps = 4/178 (2%) Query: 170 MYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLL 229 +YLV ++ G + +FP+ +A Y +LL L LH +G+V++D+KP N+LL Sbjct: 342 LYLVTDYMAGG-ELFWHLQKSVRFPEERAKFYIAELLLALQALHKRGIVYRDLKPENILL 400 Query: 230 TLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVT 289 + + + DFG+++A S T G+ + PE+ + VD WS GV Sbjct: 401 DVQGHIALCDFGLSKA--NLSVGTTTRTFCGTTDYLAPEVILDEAGYD-MMVDFWSLGVL 457 Query: 290 LYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVH 347 LY MT G PF DN +L + I +LNR+P R H Sbjct: 458 LYEMTCGWSPFYADNTQQLYKNIVFGKVRFPRGLLSVEARDLIKLLLNRNPKHRLGAH 515 >SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity protein kinase Mph1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 678 Score = 75.8 bits (178), Expect = 1e-14 Identities = 57/185 (30%), Positives = 89/185 (48%), Gaps = 11/185 (5%) Query: 138 QNVQREIQLLRILR-HKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQR 196 Q + EI LLR L + +I+L ND ++ +VME L ++L + K Sbjct: 358 QGYKNEIALLRKLSGNDRIIKLYAAEVNDTLGQLNMVMECGETDLANLLMKNMKKPINLN 417 Query: 197 QAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICY 256 Y+ Q+L+ + +H Q +VH D+KP N LL ++ LK+ DFG+A+A+ + Sbjct: 418 FIRMYWEQMLEAVQVVHDQNIVHSDLKPANFLL-VEGNLKLIDFGIAKAIGNDTTNIHRD 476 Query: 257 TGQGSPAFQPPEIAN--GAEQFSGTKV-------DIWSSGVTLYNMTTGRYPFEGDNVYR 307 + G+ + PE A SG K+ D+WS G LY M GR PF + + Sbjct: 477 SHIGTINYMAPEALTDMNAHTNSGVKLVKLGRPSDVWSLGCILYQMVYGRAPFAHLKMIQ 536 Query: 308 LLEAI 312 + AI Sbjct: 537 AIAAI 541 >SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizosaccharomyces pombe|chr 1|||Manual Length = 513 Score = 75.4 bits (177), Expect = 2e-14 Identities = 45/154 (29%), Positives = 76/154 (49%), Gaps = 8/154 (5%) Query: 150 LRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209 LRH N+I+++D+IY K + +++ V D+ +A F QLLDG+ Sbjct: 298 LRHPNIIKVLDIIY-----KRHTILQIIEYVPYDLFTFITKGHCSALKADQMFFQLLDGV 352 Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDM-FSQEDICYTG-QGSPAFQPP 267 Y+H G+ H+DIK N++L + +KI DFG A F + G GS + P Sbjct: 353 AYMHSLGIAHRDIKLDNIMLDENLNVKIIDFGTAFVFHYPFESTTLMSDGVVGSKPYVAP 412 Query: 268 EIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFE 301 E+ + + + VD+WS + + R+P++ Sbjct: 413 EVLT-QKPYDPSAVDVWSCAIVYCCIALKRFPWK 445 >SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase kinase Win1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1436 Score = 75.4 bits (177), Expect = 2e-14 Identities = 68/254 (26%), Positives = 110/254 (43%), Gaps = 31/254 (12%) Query: 87 KCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQL 146 K + ++ G ++G GS+G V ++ + AV + ++ E+ + Sbjct: 1113 KSNITIRWQQGGLIGSGSFGTVYRAVNLDTGDLMAVKEVALHKPRISRPMIKRIKGEMLV 1172 Query: 147 LRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQL 205 L + H NV+ + + EK ++ ME C G L + L G+ + Y LQL Sbjct: 1173 LELFDHPNVVSYYGIEVHREKVNIF--MELCQGSSLFEFLRY--GRIEDELVIQVYVLQL 1228 Query: 206 LDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVA-----------EALDMFSQEDI 254 L+GL Y+H GV H+D+KP N+L + +K TDFG A E L +E+ Sbjct: 1229 LEGLAYIHSCGVSHQDVKPENILFDHNGIMKFTDFGSAKMSGSASTKIFEQLTQQEEEEF 1288 Query: 255 --------------CYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPF 300 Y+ G+P + PE+ G +DIWS G + M TG P+ Sbjct: 1289 EKDSEFLQHLDQNRGYSLTGTPTYMAPELILGNPSERVGAMDIWSLGCVIVEMATGSPPW 1348 Query: 301 EG-DNVYRLLEAIS 313 DN + L+ I+ Sbjct: 1349 PRLDNHFSLMYHIA 1362 >SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase Srb10 |Schizosaccharomyces pombe|chr 1|||Manual Length = 352 Score = 74.9 bits (176), Expect = 2e-14 Identities = 56/221 (25%), Positives = 102/221 (46%), Gaps = 22/221 (9%) Query: 100 LGEGSYGKVKEMLDSQSLCRR--AVXXXXXXXXXXXPNGEQ-----NVQREIQLLRILRH 152 + G+YGKV + + S S +R A+ N +Q + RE+ L R ++H Sbjct: 11 ISSGTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIREMMLCREIQH 70 Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLE---SSPGKKFPQRQAHDYFLQLLDGL 209 +N++ LV V+ D M V E+ L ++ S ++ P Q+++G+ Sbjct: 71 ENIVSLVQVLLKDGTISM--VFEYAEHDLLQIIHFHSRSRTRQIPPSILKSILWQIINGV 128 Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAE-----ALDMFSQEDICYTGQGSPAF 264 YLH ++H+D+KP N+++T +KI D G+ L +S + + T + Sbjct: 129 AYLHENWIMHRDLKPANIMITATGKVKIGDLGLGRLIRDPILPFYSSDRVVVT----IWY 184 Query: 265 QPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNV 305 + PE+ GA ++ +D+W+ G M F+GD + Sbjct: 185 RAPELLLGAHDYT-PAIDVWAIGCIYGEMLALSPLFKGDEI 224 >SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyces pombe|chr 3|||Manual Length = 781 Score = 73.7 bits (173), Expect = 5e-14 Identities = 48/162 (29%), Positives = 80/162 (49%), Gaps = 13/162 (8%) Query: 150 LRHKNVIELVDVIYNDEKQKMY-----LVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFL 203 + H NV++ D+ + +Y VM+FC G L ++E + ++ Sbjct: 508 MEHPNVVKSYDLCIDSHIFPLYSDTWCAVMDFCPRGDLLSLIEDRHDR-LGKKDFECMIK 566 Query: 204 QLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEAL-----DMFSQEDICYTG 258 Q+L GL+Y+H QG+ H+DIKP N+L++ L+ITDFG + L D+ + E Sbjct: 567 QILRGLNYIHSQGIAHRDIKPENILISEYGVLRITDFGACDVLCNPGDDITAVESKSMGI 626 Query: 259 QGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPF 300 GS + PEI ++ D+WS+ + L+ + YPF Sbjct: 627 FGSDPYMAPEILTPG-SYNAFFADMWSTAIVLHCLYFRTYPF 667 >SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein kinase Ppk5 |Schizosaccharomyces pombe|chr 1|||Manual Length = 836 Score = 73.3 bits (172), Expect = 7e-14 Identities = 66/218 (30%), Positives = 104/218 (47%), Gaps = 18/218 (8%) Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152 +Y + D +G+GS+G+V + +D + R V +G+ V E+ +L+ L Sbjct: 517 RYEIIDTVGKGSFGQVLKCIDHK---RGQVVAIKVIKNRQKFHGQTLV--EVGILKRLCE 571 Query: 153 KNVIELVDVI----YNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDG 208 + + +VI + D + + +V E L D++ + K P + LQ L Sbjct: 572 ADPADKNNVIRYLSHFDFRGHLCIVTELLGSNLFDVIRENNYKGLPLIVVKSFALQGLQA 631 Query: 209 LDYLHGQGVVHKDIKPGNLLLT--LDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQP 266 L L GQ ++H D+KP NLLL+ L +K+ DFG + F E + YT S ++ Sbjct: 632 LRLLQGQNIIHCDLKPENLLLSHPLKARIKLIDFGSS----CFYNEKV-YTYLQSRFYRA 686 Query: 267 PEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDN 304 PEI G E G ++DIWS G L + TG F G N Sbjct: 687 PEIILGLEY--GKEIDIWSFGCILAELFTGVPLFPGGN 722 >SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gcn2 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1576 Score = 72.9 bits (171), Expect = 9e-14 Identities = 58/215 (26%), Positives = 100/215 (46%), Gaps = 26/215 (12%) Query: 170 MYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLL 228 +Y+ ME+C + LQD++ K P + F Q+L+ L Y+H +G++H+D+KPGN+ Sbjct: 724 LYIQMEYCEKLSLQDIIRD----KIPVDEMWRLFRQILEALAYIHSRGMMHRDLKPGNIF 779 Query: 229 LTLDQTLKITDFGVAEALDMF-----------SQEDICYTGQGSPAFQPPEI---ANGAE 274 L ++ +K+ DFG+A + + S ++ TG G+ + PE+ NG Sbjct: 780 LDENRNVKLGDFGLATENENYQDNNDKWKNRQSADEDLTTGVGTALYVAPELLSRRNGVR 839 Query: 275 QFSGTKVDIWSSGVTLYNM-TTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXXXX 333 KVD++S G+ L+ M T E + + + S Sbjct: 840 Y--DAKVDMYSLGIILFEMCMTFSTSMERIRIIDTIRSPSISFPSTFPFSRASHEFKVIH 897 Query: 334 HMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLV 368 +L DPT RP+ E+ +A PP + GE+ + Sbjct: 898 CLLQHDPTKRPSSQELLES---EAIPP-KVGEEFI 928 Score = 42.3 bits (95), Expect = 1e-04 Identities = 40/175 (22%), Positives = 78/175 (44%), Gaps = 16/175 (9%) Query: 138 QNVQREIQLLRILRHKNVIELVDVIYNDEKQ----KMYLVMEFCVG-VLQDMLESSPGKK 192 Q ++ E++ L+++RH + + + E + ++Y++ E+ L +L++ Sbjct: 288 QELEYELESLKVIRHDLLASIYEYQLERETRGYGWRLYVLQEYSPKFTLFSLLQTVLTLD 347 Query: 193 FPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLL--TLDQTL-KITDFGVAEAL-DM 248 +A + +L+GL LH G+ HK + N++L + +T K+ DFG L DM Sbjct: 348 VETVRA--FSNNILEGLAELHRLGISHKSLHLDNVVLFHSGHRTFAKLMDFGFTRTLRDM 405 Query: 249 FSQEDICYTGQG-----SPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRY 298 + Q PPE++ + + K DIW G+ + M G + Sbjct: 406 NASHPFNINSQSITNILPEGLYPPEVSESSFAAASRKTDIWCFGLLVLQMLCGAH 460 >SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosaccharomyces pombe|chr 1|||Manual Length = 650 Score = 72.5 bits (170), Expect = 1e-13 Identities = 55/243 (22%), Positives = 115/243 (47%), Gaps = 18/243 (7%) Query: 81 YRSRKKKCKMVGK-YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQN 139 Y +KC + + Y + +G+G++G V + +++ + V + Sbjct: 22 YTKEVRKCISIDEVYNVVRKVGDGTFGSVY-LATTKTPSKEVVAIKSMKKKLAKVSDATR 80 Query: 140 VQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAH 199 ++ LLR+ ++N++ + D +Y D+ + +++VMEF L ++ + Q Sbjct: 81 LREVHSLLRLSENENIVNIFD-LYIDQFRCLHIVMEFLDCNLYQLISTRKNDPLTLEQVQ 139 Query: 200 DYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQ-----TLKITDFGVAEALDMFSQEDI 254 D Q+ GL+++H G H+D+KP N+L++ + +KI DFG+A ++ Sbjct: 140 DIMRQIFKGLNHIHTNGFFHRDMKPENILISSNSDSSSFNVKIADFGLAREINSRPP--- 196 Query: 255 CYTGQGSPA-FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEG----DNVYRLL 309 YT S ++ PE+ + + VDI+++G + + T + F G D +Y++ Sbjct: 197 -YTEYVSTRWYRAPELLL-RDSYYSFPVDIYAAGCMAFEIATLQPIFPGNDDFDQLYKMC 254 Query: 310 EAI 312 E + Sbjct: 255 EIL 257 >SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizosaccharomyces pombe|chr 3|||Manual Length = 338 Score = 72.1 bits (169), Expect = 2e-13 Identities = 54/213 (25%), Positives = 101/213 (47%), Gaps = 11/213 (5%) Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150 V ++ + +V+G+GS+ V + Q+ R A+ + + ++ E+ LL+ L Sbjct: 27 VSQFKIRNVIGKGSWSTVFVVKHRQTKQRFALKCINKKKHDE--HKIKKLRNEVLLLQSL 84 Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLD 210 H + + +++ K+YLV + +G D+ +KF + + ++L+ L Sbjct: 85 NHPLLCKFYSEF--EDETKIYLVTDLMLG--GDLRYHISQRKFNESVIRIWMVELVSALI 140 Query: 211 YLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMF---SQEDICYTGQGSPAFQPP 267 Y+H +GV+H+D+KP N+LL K+ DF VA + S+ ++ G+P + P Sbjct: 141 YIHSKGVLHRDVKPDNILLDEKGHCKLADFNVAAKVHTSSSPSKSNMTVGRVGTPVYMAP 200 Query: 268 EIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPF 300 E A + + D WS G+T Y PF Sbjct: 201 ETLIHAVSYK--ESDWWSLGITFYECLFQVRPF 231 >SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosaccharomyces pombe|chr 1|||Manual Length = 696 Score = 70.5 bits (165), Expect = 5e-13 Identities = 41/152 (26%), Positives = 75/152 (49%), Gaps = 3/152 (1%) Query: 192 KFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQ 251 +FP+++A Y +L+ L++LH ++++D+KP N+LL D + + DFG+++A S Sbjct: 399 RFPEQRAKFYIAELVLALEHLHKHDIIYRDLKPENILLDADGHIALCDFGLSKA--NLSA 456 Query: 252 EDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEA 311 T G+ + PE+ + ++ +VD WS GV ++ M G PF +V ++ Sbjct: 457 NATTNTFCGTTEYLAPEVLLEDKGYT-KQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRN 515 Query: 312 ISRXXXXXXXXXXXXXXXXXXXHMLNRDPTLR 343 I+ +LNR+P R Sbjct: 516 IAFGKVRFPKGVLSSEGRSFVRGLLNRNPNHR 547 >SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizosaccharomyces pombe|chr 3|||Manual Length = 569 Score = 70.5 bits (165), Expect = 5e-13 Identities = 65/237 (27%), Positives = 110/237 (46%), Gaps = 14/237 (5%) Query: 79 IIYRSRKKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQ 138 ++Y+ + + + + V+G+GS+GKV ++ + R E Sbjct: 215 MLYKPNQSTPLTIDAFELLKVVGKGSFGKVMQVRKRDT--SRIYALKTMKKAHIVSRSE- 271 Query: 139 NVQREIQLLRILRHKNVIELVDVIYNDEKQ-KMYLVMEFCVG-VLQDMLESSPGKKFPQR 196 V + +L N +V + ++ + K+YLV+ F G L L+ F Sbjct: 272 -VDHTLAERTVLAQVNNPFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGC--FDTY 328 Query: 197 QAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICY 256 +A Y +LL L+ LH V+++D+KP N+LL + + DFG+ + L+M ++ D Sbjct: 329 RAKFYIAELLVALECLHEFNVIYRDLKPENILLDYTGHIALCDFGLCK-LNM-AKTDRTN 386 Query: 257 TGQGSPAFQPPEIANGAEQFSGTK-VDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312 T G+P + PE+ G TK VD W+ GV LY M TG PF +N+ + I Sbjct: 387 TFCGTPEYLAPELLLG---HGYTKVVDWWTLGVLLYEMITGLPPFYDENINEMYRKI 440 >SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces pombe|chr 1|||Manual Length = 471 Score = 69.3 bits (162), Expect = 1e-12 Identities = 44/155 (28%), Positives = 74/155 (47%), Gaps = 5/155 (3%) Query: 204 QLLDGLDYLHGQGVVHKDIKPGNLLLTLDQ-TLKITDFGVAEALDMFSQEDICYTGQGSP 262 ++L GL+YLHGQ +H+DIK N+LL+ +K+ DFGVA L + +T G+P Sbjct: 112 EVLYGLNYLHGQNKIHRDIKAANILLSSSTGNVKLADFGVAAQLSNAASRR--HTFVGTP 169 Query: 263 AFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXX 322 + PE+ + G DIWS G+T M G P + R++ I + Sbjct: 170 FWMAPEVIQ--QTSYGLAADIWSLGITAIEMANGIPPRATMHPMRVIFEIPQSEPPKLDD 227 Query: 323 XXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357 L+ +P +R + E+ +H ++++ Sbjct: 228 HFSPTFRDFVSCCLDLNPNMRWSAKELLQHPFIKS 262 >SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizosaccharomyces pombe|chr 2|||Manual Length = 461 Score = 69.3 bits (162), Expect = 1e-12 Identities = 44/133 (33%), Positives = 66/133 (49%), Gaps = 6/133 (4%) Query: 172 LVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTL 231 LV E+C D+ + K Y Q+L + YL Q + H+D+KP N+L+ Sbjct: 209 LVQEYCPQ--GDLFKQIEEKVLTLEDKCCYLKQILQAVAYLQSQRIAHRDLKPENILIGR 266 Query: 232 DQTLKITDFGVAEAL-DMFSQEDICYT--GQGSPAFQPPEIANGAEQFSGTKVDIWSSGV 288 D LK+TDFG +E + + E I + GS A+ PE A ++ G D WS G+ Sbjct: 267 DGLLKLTDFGTSEIVGNPGDNESIRFVSGAVGSLAYLAPE-AFHENEYCGLLADRWSCGI 325 Query: 289 TLYNMTTGRYPFE 301 L + TG +PF+ Sbjct: 326 LLKVLFTGYFPFK 338 >SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 445 Score = 68.5 bits (160), Expect = 2e-12 Identities = 56/176 (31%), Positives = 85/176 (48%), Gaps = 19/176 (10%) Query: 143 EIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYF 202 E+ +LR L H N+I+ V++ YN E Q ++ E G + G P+ Sbjct: 206 EMTILRKLDHPNIIK-VNMEYNSETQ-FFIFEEMVTGGDLFSYLTKLGT-VPEVTTLFIM 262 Query: 203 LQLLDGLDYLHGQGVVHKDIKPGNLLL--TLDQTLKI--TDFGVAEALDMFSQEDICYTG 258 Q+L GL YLH Q ++H+D+K N+L+ + D +I TDFGVA + + T Sbjct: 263 FQILQGLKYLHEQNIIHRDLKLENILIASSSDTIFRIILTDFGVARCMQKGKR---LSTF 319 Query: 259 QGSPAFQPPEI--ANGAEQFS-------GTKVDIWSSGVTLYNMTTGRYPFEGDNV 305 G+P + PEI G Q G +VD+WS GV ++ + +G P D V Sbjct: 320 VGTPEYTAPEIQRLKGRSQVEKENSSGYGKEVDLWSLGVIMFLLLSGNSPSFADGV 375 >SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccharomyces pombe|chr 2|||Manual Length = 605 Score = 68.5 bits (160), Expect = 2e-12 Identities = 41/157 (26%), Positives = 75/157 (47%), Gaps = 7/157 (4%) Query: 205 LLDGLDYLHGQ-GVVHKDIKPGNLLLTLDQTLKITDFGVA-EALDMFSQEDI-CYTGQGS 261 ++ GL L + ++H+D+KP N+L+ + +K+ DFGV+ + S+ +I C + Sbjct: 424 VVQGLKTLKEEHNIIHRDVKPTNVLVNSNGQVKLCDFGVSGNLVASISKTNIGCQSYMAP 483 Query: 262 PAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGD---NVYRLLEAISRXXXX 318 + NG ++ + D+WS G+T+ M G YP+ + +++ L AI Sbjct: 484 ERIRVGGPTNGVLTYT-VQADVWSLGLTILEMALGAYPYPPESYTSIFAQLSAICDGDPP 542 Query: 319 XXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355 LN++P+LRP HE+ H W+ Sbjct: 543 SLPDSFSPEARDFVNKCLNKNPSLRPDYHELANHPWL 579 >SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase Ppk6|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 68.5 bits (160), Expect = 2e-12 Identities = 65/274 (23%), Positives = 121/274 (44%), Gaps = 26/274 (9%) Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQN-----VQREIQ 145 + Y LG G+YG+VK + + + ++ V EI Sbjct: 500 IASYTTIKELGIGAYGQVKLATYKSNKVHEVILKSISKSRILLDSWMRDKDLGTVPMEIS 559 Query: 146 LLRILR---HKNVIELVDVIYNDEKQKMYLVME-FCVGV-LQDMLESSPGKKFPQRQAHD 200 +L L+ H N+++++ + ++ + YL+ E G+ L D +E P ++++ Sbjct: 560 ILHFLKAHSHPNIVKMIT--FFEDNENYYLLTEPQKPGIDLFDYIELKPS--ISEKESKA 615 Query: 201 YFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQG 260 F Q+ + +LH ++H+DIK N++L + ++ DFG + +L D T +G Sbjct: 616 IFFQIALAVAHLHSFDIIHRDIKDENVILEGNGCARLIDFG-SSSLTKNGPFD---TFRG 671 Query: 261 SPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXX 320 + F PE+ G E++ G + DIW+ G+ LY + P+ N+ +L+A R Sbjct: 672 TVGFAAPELLRG-EKYLGKEQDIWALGILLYTIVYRENPYY--NIEEILDAKLR-----I 723 Query: 321 XXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAW 354 ML+R+ R T+ E +H W Sbjct: 724 PFELSKDNVDLICRMLDRNVHDRITIEETLQHHW 757 >SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosaccharomyces pombe|chr 2|||Manual Length = 559 Score = 68.1 bits (159), Expect = 3e-12 Identities = 54/223 (24%), Positives = 109/223 (48%), Gaps = 16/223 (7%) Query: 93 KYVMGDVLGEGSYGKV--KEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQRE-IQLLRI 149 +Y++ LG+GS+G V + + L P E RE + L +I Sbjct: 20 RYLVKQKLGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSKPKPKHELLKLRESLALRKI 79 Query: 150 LRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209 +H +I+L++ + D + ++LVMEF L + + G+ F + A + LQ++ G+ Sbjct: 80 SKHPCLIDLLET-FMDPYRNIFLVMEFMDCNLFQLFKRRQGRLFTKETAFNILLQIISGI 138 Query: 210 DYLHGQGVVHKDIKPGNLL--------LTLDQTLKITDFGVAEALDMFSQEDICYTGQGS 261 +++H G +H+DIKP N+L ++ ++K+ DFG+A + S Y + Sbjct: 139 EHIHKHGFMHRDIKPENILVKRISPKPISSRYSIKLGDFGLARP-SVSSDPLTEYV--ST 195 Query: 262 PAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDN 304 ++ PE+ + ++ + VD+++ G ++ + + + F G N Sbjct: 196 RWYRAPELLLRSGSYNHS-VDLYAFGCIVFEIYSLKPLFPGRN 237 >SPBC337.04 |ppk27||serine/threonine protein kinase Ppk27 |Schizosaccharomyces pombe|chr 2|||Manual Length = 413 Score = 62.5 bits (145), Expect = 1e-10 Identities = 47/176 (26%), Positives = 84/176 (47%), Gaps = 20/176 (11%) Query: 141 QREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHD 200 ++EI L+ L H V++L++ Y ++ LV +C+G F Sbjct: 153 RQEIWALKTLSHPCVVQLLN--YYVSSAELILVENYCMGGDLYHYTKKHHSDFSLEFVGR 210 Query: 201 YFLQLLDGLDYLHGQGVVHKDIKPGNLLLT--------LDQ-------TLKITDFGVAEA 245 F +L+ + YLH + ++H+D+K N+LLT +D ++I+DF ++ Sbjct: 211 IFSELVHTVAYLHSKCLIHRDLKLENILLTQPYNVIKTIDNWKNYPNALIQISDFELSIF 270 Query: 246 LDMFSQEDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFE 301 +D S+ + + GS + PPE+ G G + D WS G+ L+ + GR PF+ Sbjct: 271 VD--SKNHLVQSSCGSQEYAPPEVYMGIAH-DGFRADAWSLGIVLFALLEGRLPFD 323 >SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Schizosaccharomyces pombe|chr 1|||Manual Length = 332 Score = 62.1 bits (144), Expect = 2e-10 Identities = 42/153 (27%), Positives = 79/153 (51%), Gaps = 10/153 (6%) Query: 138 QNVQREIQLLRILRH-KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQR 196 + ++REI++L+ L N+I L+D++ + E + L+ EF + D P Sbjct: 80 KKIKREIKILQNLAGGPNIISLLDIVRDPESKTPSLIFEFVDNI--DFRTLYP--TLSDY 135 Query: 197 QAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLT-LDQTLKITDFGVAEALDMFSQEDIC 255 Y +LL LD+ H +G++H+D+KP N+++ + L++ D+G+AE + ++ Sbjct: 136 DIRYYSYELLKALDFCHSRGIMHRDVKPHNVMIDHKKRKLRLIDWGLAEFYHAGMEYNV- 194 Query: 256 YTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGV 288 S F+ PE+ ++ +DIWS GV Sbjct: 195 --RVASRYFKGPELLVDFREYD-YSLDIWSFGV 224 >SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomyces pombe|chr 2|||Manual Length = 581 Score = 61.3 bits (142), Expect = 3e-10 Identities = 47/162 (29%), Positives = 79/162 (48%), Gaps = 12/162 (7%) Query: 137 EQNVQREIQLLRILRHKNVIELVDV-IYNDEKQKMYLVMEFCVGVLQDMLESSPG--KKF 193 E+++Q L R+ V+ LV+V YND ++L +++C + S G + Sbjct: 333 ERHLQEVSILQRLQACPFVVNLVNVWSYNDN---IFLQLDYCENGDLSLFLSELGLLQVM 389 Query: 194 PQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQED 253 + QL L+++H VH D+KP N+L+T D LK+ DFG+A +L + S D Sbjct: 390 DPFRVWKMLFQLTQALNFIHLLEFVHLDVKPSNVLITRDGNLKLGDFGLATSLPVSSMVD 449 Query: 254 ICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTT 295 + +G + PEI A G D++S G+++ T Sbjct: 450 L----EGDRVYIAPEIL--ASHNYGKPADVYSLGLSMIEAAT 485 >SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizosaccharomyces pombe|chr 2|||Manual Length = 953 Score = 60.9 bits (141), Expect = 4e-10 Identities = 51/183 (27%), Positives = 92/183 (50%), Gaps = 22/183 (12%) Query: 138 QNVQREIQLLRILR-HKNVIELVD--VIYN--DEKQKMYLVMEFCVGV-LQDMLESSPGK 191 Q V EI+ ++ L+ H++++ +D +Y+ + + ++YL+MEFC G L D + + Sbjct: 96 QLVHGEIETMKRLKGHRHIVNYIDSSALYSKSENRYEVYLLMEFCAGGGLIDFMNTRLQH 155 Query: 192 KFPQRQAHDYFLQLLDGLDYLH--GQGVVHKDIKPGNLLLTLDQTLKITDFGVA-EALD- 247 + + + + D + +H ++H+D+K N+LL + K+ DFG A E L Sbjct: 156 RLTEGEILKILADVCDAVAAMHYLDPPLIHRDLKIENVLLVAPNSYKLCDFGSACEPLAP 215 Query: 248 -------MFSQEDI-CYTGQGSPAFQPPEIAN-GAEQFSGTKVDIWSSGVTLYNMTTGRY 298 MF +++I YT +P ++ PE+ + Q K DIW+ GV Y + Sbjct: 216 ATTPDTIMFLEQNIAAYT---TPQYRAPEMIDINRRQGIDEKSDIWAIGVLAYKLCYYTT 272 Query: 299 PFE 301 PFE Sbjct: 273 PFE 275 >SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosaccharomyces pombe|chr 3|||Manual Length = 877 Score = 60.9 bits (141), Expect = 4e-10 Identities = 49/197 (24%), Positives = 93/197 (47%), Gaps = 14/197 (7%) Query: 99 VLGEGSYGKVKEMLDS-QSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILR-HKNVI 156 +LG G + +V ++ D + + AV P + +E+ + R L+ H +++ Sbjct: 571 LLGSGEFSEVFQVEDPVEKTLKYAVKKLKVKFSG--PKERNRLLQEVSIQRALKGHDHIV 628 Query: 157 ELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPG-KKFPQRQAHDYFLQLLDGLDYLHG 214 EL+D + +Y+ +E C G L LE + + + +++ GL ++H Sbjct: 629 ELMDSW--EHGGFLYMQVELCENGSLDRFLEEQGQLSRLDEFRVWKILVEVALGLQFIHH 686 Query: 215 QGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAE 274 + VH D+KP N+++T + TLKI DFG+A + + +G + PE+ A Sbjct: 687 KNYVHLDLKPANVMITFEGTLKIGDFGMASVWPVPRGME----REGDCEYIAPEVL--AN 740 Query: 275 QFSGTKVDIWSSGVTLY 291 DI+S G+T++ Sbjct: 741 HLYDKPADIFSLGITVF 757 >SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schizosaccharomyces pombe|chr 2|||Manual Length = 526 Score = 59.7 bits (138), Expect = 9e-10 Identities = 52/230 (22%), Positives = 98/230 (42%), Gaps = 27/230 (11%) Query: 99 VLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIEL 158 +LG+G GKV ++ +S R + V E ++L +H ++ L Sbjct: 160 LLGQGDVGKVY-LVRQKSNHRLFAMKILNKREMIKRHKVNRVLAEQEILTKSKHPFIVTL 218 Query: 159 VDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGV 217 + + +YL ME+C G L S P P++ A Y ++ L+YLH G Sbjct: 219 YHSFQS--RDYLYLCMEYCAGGEFFRALHSLPKHILPEKDACFYAAEVTAALEYLHLMGF 276 Query: 218 VHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGA---- 273 +++D+KP N+LL + ++DF +++ + + + + + + + P + + Sbjct: 277 IYRDLKPENILLHQSGHIMLSDFDLSKPISIVTHPTVVLPKHSTFSQEKPALDTNSYFSN 336 Query: 274 ---EQFSGTK----------------VDIWSSGVTLYNMTTGRYPFEGDN 304 F GT+ VD W+ G+ +Y + G PF+G N Sbjct: 337 FRTNSFVGTEEYIAPEVIRSCGHTVAVDWWTLGIFIYEILYGTTPFKGKN 386 >SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizosaccharomyces pombe|chr 1|||Manual Length = 566 Score = 59.7 bits (138), Expect = 9e-10 Identities = 59/232 (25%), Positives = 96/232 (41%), Gaps = 31/232 (13%) Query: 99 VLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIEL 158 +LG+G G+V + + +S A+ N + E +L H ++ L Sbjct: 200 LLGKGDVGRVYLVREKKSGKFYAMKVLSKQEMIKR-NKSKRAFAEQHILATSNHPFIVTL 258 Query: 159 VDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGV 217 +DE +YL ME+C+G L+ PG+ + +A Y ++ L+YLH G Sbjct: 259 YHSFQSDEY--LYLCMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTAALEYLHLMGF 316 Query: 218 VHKDIKPGNLLLTLDQTLKITDFGV-----------------------AEALDMFSQEDI 254 +++D+KP N+LL + ++DF + A ALD S Sbjct: 317 IYRDLKPENILLHESGHIMLSDFDLSKQSNSAGAPTVIQARNAPSAQNAYALDTKSCIAD 376 Query: 255 CYTGQ--GSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDN 304 T G+ + PE+ G S VD W+ G+ Y M PF+G N Sbjct: 377 FRTNSFVGTEEYIAPEVIKGCGHTSA--VDWWTLGILFYEMLYATTPFKGKN 426 >SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1087 Score = 58.4 bits (135), Expect = 2e-09 Identities = 58/223 (26%), Positives = 99/223 (44%), Gaps = 12/223 (5%) Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPN-GEQNVQREIQLLRILR 151 +Y + D LG+GS+G+V +D ++ A+ E + ++I+ L Sbjct: 698 RYEVVDFLGKGSFGQVLRCIDYETGKLVALKIIRNKKRFHMQALVETKILQKIREWDPLD 757 Query: 152 HKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211 +++ D Y + + + E L ++++S+ K P QL+ L Sbjct: 758 EYCMVQYTDHFYF--RDHLCVATELLGKNLYELIKSNGFKGLPIVVIKSITRQLIQCLTL 815 Query: 212 LHGQGVVHKDIKPGNLLLT--LDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269 L+ + V+H D+KP N+LL +K+ DFG + F E + YT S ++ PE+ Sbjct: 816 LNEKHVIHCDLKPENILLCHPFKSQVKVIDFGSS----CFEGECV-YTYIQSRFYRSPEV 870 Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312 G GT +D+WS G + M TG F G+N L I Sbjct: 871 ILGMGY--GTPIDVWSLGCIIAEMYTGFPLFPGENEQEQLACI 911 >SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1316 Score = 58.0 bits (134), Expect = 3e-09 Identities = 35/103 (33%), Positives = 61/103 (59%), Gaps = 8/103 (7%) Query: 170 MYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLL 228 +YLVMEF G +L+S P+ A Y ++ GL++LH G++H+DIKP N+L Sbjct: 638 LYLVMEFMNGGDCASLLKSL--YTIPESWAKIYIAEVALGLEHLHRLGIIHRDIKPDNIL 695 Query: 229 LTLDQTLKITDFGVAEALDMFSQEDICYTGQGS----PAFQPP 267 +++ LK+ DFG+++ L + +++ G+ + P+FQ P Sbjct: 696 MSITGHLKLADFGLSQ-LGLTTRQLRLQKGKNNILSPPSFQSP 737 Score = 32.7 bits (71), Expect = 0.12 Identities = 19/69 (27%), Positives = 30/69 (43%), Gaps = 2/69 (2%) Query: 244 EALDMFSQEDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGD 303 +++ F Q D G+P + PE G+ Q VD W+ G L+ G PF + Sbjct: 817 QSVPFFRQPDAPKRFVGTPDYLAPETLRGSTQ--DDMVDWWALGCVLFEFLFGYPPFHAE 874 Query: 304 NVYRLLEAI 312 ++ E I Sbjct: 875 TPEKVFENI 883 >SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schizosaccharomyces pombe|chr 2|||Manual Length = 470 Score = 56.8 bits (131), Expect = 6e-09 Identities = 57/225 (25%), Positives = 100/225 (44%), Gaps = 29/225 (12%) Query: 99 VLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQL-LRILRHKNVIE 157 ++G G+YG V + D AV Q RE+ L R+ H +I Sbjct: 23 IIGAGAYGVVYKAEDIYDGTLYAVKALCKDGLNEKQKKLQ--ARELALHARVSSHPYIIT 80 Query: 158 LVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAH---DYFLQLLDGLDYLHG 214 L V+ ++ +Y+V+++C D+ KK Q +H FLQL+ +++ H Sbjct: 81 LHRVLETEDA--IYVVLQYCPN--GDLFTYITEKKVYQGNSHLIKTVFLQLISAVEHCHS 136 Query: 215 QGVVHKDIKPGNLLLTLD-QTLKITDFGVAEALDMFSQEDICYT-GQGSPAFQ------- 265 G+ H+D+KP N+++ D T+ + DFG+A + +S + C + SP Q Sbjct: 137 VGIYHRDLKPENIMVGNDVNTVYLADFGLA-TTEPYSSDFGCGSLFYMSPECQREVKKLS 195 Query: 266 ---------PPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFE 301 P I + + F+ D+W+ G+ L N+ R P++ Sbjct: 196 SLSDMLPVTPEPIESQSSSFATAPNDVWALGIILINLCCKRNPWK 240 >SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 340 Score = 54.4 bits (125), Expect = 3e-08 Identities = 42/171 (24%), Positives = 75/171 (43%), Gaps = 12/171 (7%) Query: 137 EQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLESSPGKKFPQ 195 ++ + RE+ +L R ++ K + L ME+ G L +L G P Sbjct: 104 QKQILRELGVLHHCRSPYIVGFYGAF--QYKNNISLCMEYMDCGSLDAILRE--GGPIPL 159 Query: 196 RQAHDYFLQLLDGLDYLHGQ-GVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDI 254 ++ GL YL+ ++H+D+KP N+++ +K+ DFGV+ L + Sbjct: 160 DILGKIINSMVKGLIYLYNVLHIIHRDLKPSNVVVNSRGEIKLCDFGVSGEL----VNSV 215 Query: 255 CYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNV 305 T G+ + PE G + K DIWS G+++ + T P+ N+ Sbjct: 216 AQTFVGTSTYMSPERIRGGKY--TVKSDIWSLGISIIELATQELPWSFSNI 264 >SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1072 Score = 54.0 bits (124), Expect = 4e-08 Identities = 43/147 (29%), Positives = 74/147 (50%), Gaps = 18/147 (12%) Query: 142 REIQLLRIL-RHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLES--SPGKKFPQRQA 198 REI LL+ H N++ +D Q +Y+V+E C L D++E + F Sbjct: 694 REITLLQQSDNHPNIVRYYCKQKSD--QFLYIVIELCKCNLSDLIEKPIAYDDLFKSIDL 751 Query: 199 HDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQT---------LKITDFGVAEALDMF 249 Q+ G+ +LH +VH+D+KP N+LL ++ + I+DFG+++ LD F Sbjct: 752 VSLLYQIAFGVSHLHSLDLVHRDLKPQNILLVVNNSPNLSKTRVRALISDFGLSKKLD-F 810 Query: 250 SQEDI---CYTGQGSPAFQPPEIANGA 273 +Q + + GS ++ PEI +G+ Sbjct: 811 NQSSLRNTTFEAAGSYGWRSPEILSGS 837 >SPAC23A1.06c |cmk2|mkp2|MAPK-activated protein kinase Cmk2|Schizosaccharomyces pombe|chr 1|||Manual Length = 504 Score = 53.6 bits (123), Expect = 6e-08 Identities = 39/140 (27%), Positives = 72/140 (51%), Gaps = 12/140 (8%) Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRA-VXXXXXXXXXXXPNGEQNVQREIQLLRILR 151 KY + + LG+G++ +V + + S+ R+ V Q V +E+ ++R ++ Sbjct: 64 KYQLIENLGDGAFSQVYK---AYSIDRKEHVAVKVIRKYEMNKKQRQGVFKEVNIMRRVK 120 Query: 152 HKNVIELVDVIYNDEKQKMYLVMEFCVG--VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209 HKNV+ L D + + + +LVME G + ++ + F + A +Q+ + + Sbjct: 121 HKNVVNLFDFV--ETEDFYHLVMELAEGGELFHQIVNFT---YFSENLARHIIIQVAEAV 175 Query: 210 DYLHGQ-GVVHKDIKPGNLL 228 +LH G+VH+DIKP NLL Sbjct: 176 KHLHDVCGIVHRDIKPENLL 195 Score = 43.6 bits (98), Expect = 6e-05 Identities = 29/123 (23%), Positives = 48/123 (39%), Gaps = 9/123 (7%) Query: 237 ITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTG 296 I DFG ++ + C G+ + PEI N ++ VD+W+ G L+ M G Sbjct: 236 IADFGFSKVVWNSKTATPC----GTVGYAAPEIVN--DELYSKNVDMWAMGCVLHTMLCG 289 Query: 297 RYPFEGDNVYRLLEAISRXXXXXXX---XXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHA 353 PF +N+ L + H+L DP R +H+ +H Sbjct: 290 FPPFFDENIKDLASKVVNGEFEFLSPWWDDISDSAKDLITHLLTVDPRERYDIHQFFQHP 349 Query: 354 WVQ 356 W++ Sbjct: 350 WIK 352 >SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 306 Score = 53.2 bits (122), Expect = 8e-08 Identities = 38/158 (24%), Positives = 77/158 (48%), Gaps = 8/158 (5%) Query: 146 LLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQL 205 +L + H ++ +VD ++E +YL+ F VL D+++ + LQ+ Sbjct: 59 ILESIGHPHIERIVDSFIDNEAGSVYLITSFKSFVLSDVMD-----EISIDTKCKIVLQI 113 Query: 206 LDGLDYLHGQGVVHKDIKPGNLLL-TLDQTLKITDFGVAEALDMFSQEDICYTGQ-GSPA 263 L+YL G++H+DI P N+LL +++ ++DF +A + +E Q G+ Sbjct: 114 SSALEYLEKHGILHRDIHPNNILLDSMNGPAYLSDFSIAWSKQHPGEEVQELIPQIGTGH 173 Query: 264 FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFE 301 ++ E G + G +VD W+ G+ + + + + F+ Sbjct: 174 YRAIETLFGCHSY-GHEVDRWTFGILIAELFSNQALFD 210 >SPAC823.03 |ppk15||serine/threonine protein kinase Ppk15 |Schizosaccharomyces pombe|chr 1|||Manual Length = 534 Score = 53.2 bits (122), Expect = 8e-08 Identities = 56/226 (24%), Positives = 94/226 (41%), Gaps = 23/226 (10%) Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152 KY++ D LG G++G+V D ++ A+ P E+ +L +L + Sbjct: 129 KYLILDTLGHGTFGQVARCQDLKTQQIVAIKVIKNK-----PAFYNQCVMEVSILELLNN 183 Query: 153 K-------NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQL 205 K ++I L D + K + LV E L ++++ + + + QL Sbjct: 184 KYDPEDKRHLIRLYDQFMH--KNHLCLVFELLSINLYELIKQNQFRGLHLSLVRSFATQL 241 Query: 206 LDGLDYLHGQGVVHKDIKPGNLLL--TLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA 263 L L ++H D+KP N+LL +K+ DFG A + YT S Sbjct: 242 LSCTSLLKQARIIHCDLKPENILLQDLSSPIVKVIDFGSA-----CHERQTVYTYIQSRF 296 Query: 264 FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLL 309 ++ PE+ G G +D+WS G L + G F G++ Y L Sbjct: 297 YRSPEVILGLHYNCG--IDMWSLGCILAELFLGLPLFPGNSEYNQL 340 >SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1032 Score = 52.0 bits (119), Expect = 2e-07 Identities = 26/83 (31%), Positives = 47/83 (56%), Gaps = 1/83 (1%) Query: 165 DEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKP 224 D + LVM++ G + L G P++ Y +LL+ ++ LH G++H DIKP Sbjct: 597 DSGDYLCLVMDYFNGGDCETLIQKLGP-LPEQWVCQYAAELLNAIELLHQDGIIHHDIKP 655 Query: 225 GNLLLTLDQTLKITDFGVAEALD 247 N+L+ +++TDFG++E ++ Sbjct: 656 ANMLVDETGHIRLTDFGLSENVE 678 Score = 40.7 bits (91), Expect = 4e-04 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 3/55 (5%) Query: 260 GSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314 G+P + PEI G + G DIW+ G ++ M TG PFE + V + I R Sbjct: 779 GTPNYMAPEILMGVDTQMG---DIWAMGCVIFEMLTGTRPFEANTVKAIWARIER 830 >SPCC1322.08 |srk1|mkp1|MAPK-activated protein kinase Srk1|Schizosaccharomyces pombe|chr 3|||Manual Length = 580 Score = 50.8 bits (116), Expect = 4e-07 Identities = 31/93 (33%), Positives = 52/93 (55%), Gaps = 8/93 (8%) Query: 139 NVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVG--VLQDMLESSPGKKFPQR 196 N+ +E+Q++R ++H N+I+L++ I E YLV+E G + ++ + F + Sbjct: 177 NILKEVQIMRRVKHPNIIQLLEFIQTPE--YYYLVLELADGGELFHQIVRLT---YFSED 231 Query: 197 QAHDYFLQLLDGLDYLHGQ-GVVHKDIKPGNLL 228 + Q+ + YLH GVVH+DIKP NLL Sbjct: 232 LSRHVITQVAHAIRYLHEDCGVVHRDIKPENLL 264 Score = 48.0 bits (109), Expect = 3e-06 Identities = 35/146 (23%), Positives = 59/146 (40%), Gaps = 12/146 (8%) Query: 235 LKITDFGVAEAL-DMFSQEDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNM 293 +++ DFG+++ + D +Q T G+ + PEI G VD+W+ G LY + Sbjct: 304 IRLADFGLSKVVWDSHTQ-----TPCGTMGYTAPEIVRDERYSKG--VDMWALGCVLYTI 356 Query: 294 TTGRYPFEGDNVYRLLEAISRXXXXXXX---XXXXXXXXXXXXHMLNRDPTLRPTVHEIR 350 G PF +++ L + +SR H+L DP R +H+ Sbjct: 357 LCGFPPFYDESISLLTKKVSRGEYSFLSPWWDDISKSAKDLISHLLTVDPESRYDIHQFL 416 Query: 351 RHAWVQAT-PPFEPGEKLVNPRSRRS 375 H W+ + P P N R + Sbjct: 417 AHPWISGSREPTFPATDAPNTAQREN 442 >SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|Schizosaccharomyces pombe|chr 3|||Manual Length = 624 Score = 50.4 bits (115), Expect = 5e-07 Identities = 29/99 (29%), Positives = 53/99 (53%), Gaps = 2/99 (2%) Query: 149 ILRHKNVIELVDVIYN-DEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLD 207 IL + N LV + Y +K+K+YL ME+ G ++ G + Q Y +++ Sbjct: 213 ILTNTNSEWLVKLYYAFQDKEKVYLAMEYVPGGDFRTFLTTKGL-LHENQTRFYLAEMVA 271 Query: 208 GLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEAL 246 + +H G +H+D+KP N L+ +K++DFG++ A+ Sbjct: 272 AISAVHKLGYMHRDLKPENFLIDQKGHIKLSDFGLSTAI 310 Score = 33.9 bits (74), Expect = 0.051 Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 2/46 (4%) Query: 260 GSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNV 305 GSP + PE+ G +++ T VD WS G Y G PF G + Sbjct: 359 GSPEYMAPEVVYG-KKYDRT-VDYWSLGCICYECLVGYPPFSGSTL 402 >SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomyces pombe|chr 1|||Manual Length = 607 Score = 50.0 bits (114), Expect = 7e-07 Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 2/99 (2%) Query: 149 ILRHKNVIELVDVIYN-DEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLD 207 IL N LV ++Y + +YL MEF G L S+ G A Y ++ Sbjct: 259 ILTTANSEWLVRLLYAFQDTSNIYLAMEFVPGGDFRTLLSNSGV-LRDHHAKFYATEMFL 317 Query: 208 GLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEAL 246 +D LH G +H+D+KP N L+ +K+TDFG++ + Sbjct: 318 AIDALHQLGYIHRDLKPENFLVGASGHIKLTDFGLSSGI 356 Score = 39.5 bits (88), Expect = 0.001 Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 3/59 (5%) Query: 248 MFSQEDI-CYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNV 305 + SQ+ + ++ GSP + PE+ G E ++ + VD WS G +Y +G PF G NV Sbjct: 392 LLSQDPVYAHSVVGSPDYMAPEVLRG-ENYNHS-VDYWSLGCIMYECLSGFPPFSGSNV 448 >SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosaccharomyces pombe|chr 3|||Manual Length = 477 Score = 49.6 bits (113), Expect = 1e-06 Identities = 37/103 (35%), Positives = 48/103 (46%), Gaps = 7/103 (6%) Query: 201 YFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQT-LKITDFGVAEALDMFSQEDICYTGQ 259 Y Q+ LD L V+H DIKP N+L+ + LKI D G A D E Y Sbjct: 266 YAYQMFMALDLLKQCNVIHSDIKPDNMLVNEKRNILKICDLG--SASDASENEITPYL-- 321 Query: 260 GSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEG 302 S ++ PEI G +D WS G +LY + TG+ F G Sbjct: 322 VSRFYRAPEIILGFPY--SCPIDTWSVGCSLYELYTGQILFPG 362 >SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizosaccharomyces pombe|chr 3|||Manual Length = 1338 Score = 48.4 bits (110), Expect = 2e-06 Identities = 28/77 (36%), Positives = 43/77 (55%), Gaps = 1/77 (1%) Query: 167 KQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGN 226 K +YLVME+ G L + G Y + + L LH +G++H+DIKP N Sbjct: 660 KDYLYLVMEYLNGGDCGSLLKTMGV-LDLDWIRTYIAETVLCLGDLHDRGIIHRDIKPEN 718 Query: 227 LLLTLDQTLKITDFGVA 243 LL++ + LK+TDFG++ Sbjct: 719 LLISQNGHLKLTDFGLS 735 >SPBP23A10.10 |ppk32||serine/threonine protein kinase Ppk32 |Schizosaccharomyces pombe|chr 2|||Manual Length = 749 Score = 47.6 bits (108), Expect = 4e-06 Identities = 41/176 (23%), Positives = 85/176 (48%), Gaps = 25/176 (14%) Query: 140 VQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESS----------- 188 +++++ L LRH +++++V+ + + K M V +LQD ++SS Sbjct: 78 LRKDVSSLSRLRHPSLLQVVEPL-EESKSSMSFVTRRIQSMLQDFIKSSNGGFSNYGSSA 136 Query: 189 ----PGKKFPQRQAHDYFLQLLDGLDYLHGQG-VVHKDIKPGNLLLTLDQTLKITDFGVA 243 G + + LQ++DGL +LHG V+H +I+P ++++ K+ F + Sbjct: 137 NGKSSGNALEEVEIQKGLLQIIDGLVFLHGSAKVIHYNIRPSSVVVDAKGDWKLCGFSFS 196 Query: 244 EALDM----FSQED--ICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNM 293 ++++ F+ D I + Q S F PE + +G + D++S G +Y++ Sbjct: 197 QSVESARYEFNDYDFGIPSSLQQSMDFLAPEYI--THEIAGPESDVFSFGCLIYSI 250 >SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schizosaccharomyces pombe|chr 1|||Manual Length = 690 Score = 47.6 bits (108), Expect = 4e-06 Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 13/147 (8%) Query: 89 KMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLR 148 K +Y + +LG G++GKV + D QS R P + E+++L+ Sbjct: 357 KFANRYTVVRLLGHGTFGKVIQCYD-QSTGRHCAIKVTRAI----PKYREASLIELRVLQ 411 Query: 149 ILRHKN------VIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYF 202 + H + I+L D Y D ++ + +V + + D L+++ FP + Sbjct: 412 TIAHSDPTNENKCIQLRD--YFDYRKHICIVTDLFGWSVFDFLKNNNYIPFPLKHIQMLS 469 Query: 203 LQLLDGLDYLHGQGVVHKDIKPGNLLL 229 QL + +LH G+VH D+KP N+LL Sbjct: 470 QQLFKSVAFLHSLGLVHTDLKPENVLL 496 >SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizosaccharomyces pombe|chr 2|||Manual Length = 872 Score = 47.2 bits (107), Expect = 5e-06 Identities = 55/243 (22%), Positives = 102/243 (41%), Gaps = 22/243 (9%) Query: 90 MVGKY--VMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLL 147 ++GKY + + EG + V + + + N + V+ EI+ + Sbjct: 19 VIGKYNVTIEKYIAEGGFSHVYLVQTNSKTDGSPITAVLKRMYSPDENALRFVKTEIETM 78 Query: 148 RILR-HKNVIELVD-VIYNDEKQ------KMYLVMEFCVGV-LQDMLESSPGKKFPQRQA 198 +L+ + +V+ +D I+ EK ++ L+ME+C G L D + + + + Sbjct: 79 ELLKSNPHVVSYIDSCIFPLEKAGVNTGFEILLLMEYCAGGGLIDFMNQRLQTRLSEHEV 138 Query: 199 HDYFLQLLDGLDYLH--GQGVVHKDIKPGNLLLTLDQTLKITDFG-VAEALDMFSQEDIC 255 ++ G+ LH ++H+D+K N+LL+ + T K+ DFG V E + Sbjct: 139 LKIISDIVQGVASLHYLRPPLIHRDLKVENVLLSFN-TFKLCDFGSVTEPMHAAENSSEI 197 Query: 256 YTGQGSP------AFQPPEIANGAEQFS-GTKVDIWSSGVTLYNMTTGRYPFEGDNVYRL 308 + S ++ PE+ N K D+W+ GV LY + PFE + Sbjct: 198 QALEKSINTFTTYQYRAPEMINLYSGLGIDEKSDMWALGVLLYKLCYYTTPFETQGPNAI 257 Query: 309 LEA 311 L A Sbjct: 258 LTA 260 >SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosaccharomyces pombe|chr 1|||Manual Length = 469 Score = 46.0 bits (104), Expect = 1e-05 Identities = 25/75 (33%), Positives = 42/75 (56%), Gaps = 3/75 (4%) Query: 170 MYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLL 228 +YL+MEF G L ML + F + Y + + + +H G +H+DIKP N+L Sbjct: 166 LYLIMEFLPGGDLMTMLINYD--TFSEDVTRFYMAECVLAIADVHRMGYIHRDIKPDNIL 223 Query: 229 LTLDQTLKITDFGVA 243 + D +K++DFG++ Sbjct: 224 IDRDGHIKLSDFGLS 238 >SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 507 Score = 45.2 bits (102), Expect = 2e-05 Identities = 38/162 (23%), Positives = 67/162 (41%), Gaps = 10/162 (6%) Query: 95 VMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKN 154 + +VL E S+GK K ++ S + V + + E+++L +LR + Sbjct: 99 IQSEVLKESSFGKEKIPVNEDSRKPKYVAIKKIYAT----SSPARIYNELEILYLLRGSS 154 Query: 155 VIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHG 214 VI + +E Q + ++ + + + F R YF L + Sbjct: 155 VIAPLITALRNEDQVLVVLPYYEHTDFRQYYST-----FSYRDMSIYFRCLFQAMQQTQT 209 Query: 215 QGVVHKDIKPGNLLLTL-DQTLKITDFGVAEALDMFSQEDIC 255 G++H+DIKP N L + + + DFG+AE D Q C Sbjct: 210 LGIIHRDIKPSNFLFDVRTKHGVLVDFGLAERYDGRQQSHSC 251 Score = 35.1 bits (77), Expect = 0.022 Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 3/53 (5%) Query: 260 GSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPF--EGDNVYRLLE 310 G+ F+ PE+ S KVDIWS+GV L + T R+P D+V L+E Sbjct: 290 GTRGFRAPEVLFKCSSQS-PKVDIWSAGVILLSFLTKRFPMFNSKDDVDALME 341 >SPBC530.14c |dsk1||SR protein-specific kinase Dsk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 544 Score = 44.0 bits (99), Expect = 5e-05 Identities = 28/87 (32%), Positives = 45/87 (51%), Gaps = 3/87 (3%) Query: 150 LRHKNVIELVDVIYNDEKQKMYLVMEFCV--GVLQDMLESSPGKKFPQRQAHDYFLQLLD 207 L K++I L+D + ++ M F V L +++S + P QLL Sbjct: 140 LGKKHIISLLDYFVHRGPNGAHVCMVFEVLGENLLSLIQSYGHRGVPVGIVKQIAYQLLI 199 Query: 208 GLDYLHGQ-GVVHKDIKPGNLLLTLDQ 233 LDYLH + G++H D+KP N+L+ +DQ Sbjct: 200 ALDYLHRECGIIHTDLKPENVLICIDQ 226 Score = 27.1 bits (57), Expect = 5.8 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 7/71 (9%) Query: 234 TLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNM 293 T+KI D G A D+ T Q ++ PE+ G G D WS ++ + Sbjct: 355 TVKIADLGNACWTRKHFTNDV-QTRQ----YRSPEVILGCRW--GASADCWSFACIIFEL 407 Query: 294 TTGRYPFEGDN 304 TG Y F+ N Sbjct: 408 LTGDYLFDPRN 418 >SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 400 Score = 42.7 bits (96), Expect = 1e-04 Identities = 51/220 (23%), Positives = 93/220 (42%), Gaps = 16/220 (7%) Query: 89 KMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLR 148 K+ KY +G +G GS+G++ L++ + + AV ++ E ++ Sbjct: 7 KIGNKYRIGRKIGSGSFGQIYLGLNTVNGEQVAVKLEPLKAR------HHQLEYEFRVYN 60 Query: 149 ILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDG 208 IL+ I + + +VM+ L+D+ G+KF + QL+ Sbjct: 61 ILKGNIGIPTIRW-FGVTNSYNAMVMDLLGPSLEDLF-CYCGRKFTLKTVLLLADQLISR 118 Query: 209 LDYLHGQGVVHKDIKPGNLLLTL-DQTLKITDFGVAEAL-DMFSQEDICYTGQ----GSP 262 ++Y+H + +H+DIKP N L+ + + DFG+A+ D + I Y G+ Sbjct: 119 IEYVHSKSFLHRDIKPDNFLMKKHSNVVTMIDFGLAKKYRDFKTHVHIPYRDNKNLTGTA 178 Query: 263 AFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEG 302 + G EQ + D+ S G L G P++G Sbjct: 179 RYASINTHIGIEQ--SRRDDLESLGYVLLYFCRGSLPWQG 216 >SPAC3H1.13 |ppk13||serine/threonine protein kinase Ppk13 |Schizosaccharomyces pombe|chr 1|||Manual Length = 344 Score = 41.9 bits (94), Expect = 2e-04 Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 9/93 (9%) Query: 218 VHKDIKPGNLLLTLD-QTLKITDFGVAEALDMFSQ---EDICYTGQGSP----AFQPPEI 269 +H DIKP NLLL + + + +TDFG + +F+ E I + S F+ PE+ Sbjct: 191 IHGDIKPDNLLLHENSREIVLTDFGSICLVPIFASNNSEAIAIQDKASENCTMPFRAPEL 250 Query: 270 ANGAEQFSGT-KVDIWSSGVTLYNMTTGRYPFE 301 + + T K DIWS G TLY + PFE Sbjct: 251 FHVKAGSTITEKADIWSFGCTLYTIMFHASPFE 283 >SPBC21C3.18 |spo4||serine/threonine protein kinase Spo4|Schizosaccharomyces pombe|chr 2|||Manual Length = 429 Score = 41.9 bits (94), Expect = 2e-04 Identities = 29/107 (27%), Positives = 55/107 (51%), Gaps = 8/107 (7%) Query: 140 VQREIQLLRILRHKN-VIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQA 198 +Q E+++L LR + V+ ++ + + ++ + +V+ F +Q K+ + Sbjct: 106 IQTELEMLHELRGSDCVLNMITAVRHQDQ--VLIVLPF----IQHAEFRDFYMKYSLPEI 159 Query: 199 HDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLT-LDQTLKITDFGVAE 244 Y LL GL ++ +G++H+DIKPGN Q I DFG+A+ Sbjct: 160 GAYLRDLLKGLAHIDAKGIIHRDIKPGNFAWNPYTQRGVILDFGLAQ 206 Score = 32.7 bits (71), Expect = 0.12 Identities = 15/41 (36%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 260 GSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPF 300 G+ F+ PE+ + + + +D+WS GV L T RYPF Sbjct: 263 GTRGFRAPEVLFRCQNQTSS-IDVWSVGVILLCFLTHRYPF 302 >SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosaccharomyces pombe|chr 2|||Manual Length = 365 Score = 41.5 bits (93), Expect = 3e-04 Identities = 52/218 (23%), Positives = 90/218 (41%), Gaps = 18/218 (8%) Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152 KY +G +G GS+G + L + + V P ++ E ++ RIL Sbjct: 10 KYRIGRKIGSGSFGDI--YLGTNVVSGEEVAIKLESTRAKHPQ----LEYEYRVYRILSG 63 Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212 I V + E +VM+ L+D+ +KF + QL+ ++++ Sbjct: 64 GVGIPFVRW-FGVECDYNAMVMDLLGPSLEDLFNFC-NRKFSLKTVLLLADQLISRIEFI 121 Query: 213 HGQGVVHKDIKPGNLLLTLDQ---TLKITDFGVAEAL-DMFSQEDICYTGQ----GSPAF 264 H + +H+DIKP N L+ + + + I DFG+A+ D + I Y G+ + Sbjct: 122 HSKSFLHRDIKPDNFLMGIGKRGNQVNIIDFGLAKKYRDHKTHLHIPYRENKNLTGTARY 181 Query: 265 QPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEG 302 G EQ + D+ S G L G P++G Sbjct: 182 ASINTHLGIEQ--SRRDDLESLGYVLVYFCRGSLPWQG 217 >SPBC336.14c |ppk26||serine/threonine protein kinase Ppk26|Schizosaccharomyces pombe|chr 2|||Manual Length = 589 Score = 39.1 bits (87), Expect = 0.001 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 2/54 (3%) Query: 191 KKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAE 244 +K P+R+ +YF QL L YLH G + P +L +DQT +I G A+ Sbjct: 328 RKIPERELWNYFFQLTIALSYLHKSGFACNKLTPSRIL--VDQTERIRISGCAD 379 >SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 38.3 bits (85), Expect = 0.002 Identities = 34/144 (23%), Positives = 65/144 (45%), Gaps = 11/144 (7%) Query: 169 KMYLVMEFC-VGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH--GQGVVHKDIKPG 225 ++ +++E+C G L D L + + +++ + + + +H ++H+D+K Sbjct: 111 EVLVLLEYCPCGGLIDFLNTRLQVRLSEQEILKIASDVTEAVAVMHYLKPPLIHRDLKIE 170 Query: 226 NLLLTLDQTLKITDFG-----VAEALDMFSQEDICYTGQGSPAFQ--PPEIANGAEQFS- 277 N+LL + K+ DFG + A + + Y + +Q PE+ N + F Sbjct: 171 NVLLAAPNSYKLCDFGSACHPIPGAKTAAEAKQLEYDIEKFTTWQYRCPEMINVHKGFGI 230 Query: 278 GTKVDIWSSGVTLYNMTTGRYPFE 301 K DIW+ GV Y + PFE Sbjct: 231 DEKSDIWALGVLFYKLCYYTTPFE 254 >SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces pombe|chr 1|||Manual Length = 639 Score = 38.3 bits (85), Expect = 0.002 Identities = 22/67 (32%), Positives = 38/67 (56%), Gaps = 7/67 (10%) Query: 170 MYLVMEFCVGVLQD-MLESSPGKKFP----QRQAH-DYFLQLLDGLDYLH-GQGVVHKDI 222 +Y+ M+ C L+ ++ + FP Q Q H D F +++G+ Y+H G ++H+DI Sbjct: 359 IYIQMQLCFDDLESYLIRRNHFLSFPLCKEQIQLHTDLFRMIINGVMYVHEGVNLIHRDI 418 Query: 223 KPGNLLL 229 KP N+ L Sbjct: 419 KPSNIFL 425 >SPBC119.07 |ppk19||serine/threonine protein kinase Ppk19|Schizosaccharomyces pombe|chr 2|||Manual Length = 1706 Score = 36.3 bits (80), Expect = 0.010 Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 2/70 (2%) Query: 171 YLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLT 230 YLV + L D + + P + +++ QLL G+ H GV H DIK N+L+T Sbjct: 98 YLVRPYVTHNLYDRISTRPFLELTEKKW--IMFQLLKGISDCHRLGVCHGDIKSENILIT 155 Query: 231 LDQTLKITDF 240 ++DF Sbjct: 156 SWNWAYLSDF 165 >SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizosaccharomyces pombe|chr 2|||Manual Length = 446 Score = 35.9 bits (79), Expect = 0.013 Identities = 49/219 (22%), Positives = 92/219 (42%), Gaps = 20/219 (9%) Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153 Y +G +GEGS+G + E + L + V P ++ E + ++L Sbjct: 12 YKVGRRIGEGSFGVIFE--GTNLLNNQQVAIKFEPRRSDAPQ----LRDEYRTYKLLAGC 65 Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213 I V + E LV++ L+D+L+ G+KF + Q+L + +H Sbjct: 66 TGIPNV-YYFGQEGLHNILVIDLLGPSLEDLLDLC-GRKFSVKTVAMAAKQMLARVQSIH 123 Query: 214 GQGVVHKDIKPGNLLLTLDQT-----LKITDFGVAEAL-DMFSQEDICYTGQ----GSPA 263 + +V++DIKP N L+ + + + DFG+ + D +++ I Y + G+ Sbjct: 124 EKSLVYRDIKPDNFLIGRPNSKNANMIYVVDFGMVKFYRDPVTKQHIPYREKKNLSGTAR 183 Query: 264 FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEG 302 + G EQ + D+ + G G P++G Sbjct: 184 YMSINTHLGREQ--SRRDDLEALGHVFMYFLRGSLPWQG 220 >SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizosaccharomyces pombe|chr 2|||Manual Length = 435 Score = 34.3 bits (75), Expect = 0.039 Identities = 48/219 (21%), Positives = 94/219 (42%), Gaps = 20/219 (9%) Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153 Y +G +GEGS+G + + ++ L + + P ++ E + ++L Sbjct: 12 YRVGRKIGEGSFGVIFDGMNL--LNNQLIAIKFEPKKSEAPQ----LRDEYRTYKLLVGN 65 Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213 I V + E LV++ L+D+ E G++F + Q+L + +H Sbjct: 66 AGIPNV-YYFGQEGLHNILVIDLLGPSLEDLFEWC-GRRFSVKTVAMTAKQMLSRVQTIH 123 Query: 214 GQGVVHKDIKPGNLLLTLDQT-----LKITDFGVAEAL-DMFSQEDICYTGQ----GSPA 263 + +V++DIKP N L+ + + + DFG+A+ D +++ I Y+ + G+ Sbjct: 124 EKNLVYRDIKPDNFLIGRPSSRNANMVYMVDFGMAKYYRDPKTKQHIPYSERKSLSGTAR 183 Query: 264 FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEG 302 + G EQ + D+ S G G P++G Sbjct: 184 YMSINTHLGREQ--SRRDDLESLGHVFMYFLRGSLPWQG 220 >SPAC1805.05 |cki3||serine/threonine protein kinase Cki3|Schizosaccharomyces pombe|chr 1|||Manual Length = 439 Score = 33.9 bits (74), Expect = 0.051 Identities = 21/87 (24%), Positives = 41/87 (47%), Gaps = 6/87 (6%) Query: 163 YNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDI 222 Y E LVM+ L+D+ + G++F + Q++ + +H + +++DI Sbjct: 77 YGQEGMYNLLVMDLLGPSLEDLFDYC-GRRFSPKTVAMIAKQMITRIQSVHERHFIYRDI 135 Query: 223 KPGNLLL-----TLDQTLKITDFGVAE 244 KP N L+ + + DFG+A+ Sbjct: 136 KPDNFLIGFPGSKTENVIYAVDFGMAK 162 >SPAC27E2.09 |mak2|phk1|histidine kinase Mak2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 2310 Score = 31.9 bits (69), Expect = 0.21 Identities = 18/65 (27%), Positives = 37/65 (56%), Gaps = 5/65 (7%) Query: 248 MFSQEDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYR 307 ++ ++IC+ Q F P +I N ++ DI+S G+ Y + T +YP+ G ++ R Sbjct: 187 LYQVQNICHKLQ---FFSPEQIGNVGRPLD-SRSDIYSLGILFYVILTKQYPWGGQSM-R 241 Query: 308 LLEAI 312 ++++I Sbjct: 242 IVQSI 246 >SPAC20G4.03c |hri1||eIF2 alpha kinase Hri1|Schizosaccharomyces pombe|chr 1|||Manual Length = 704 Score = 31.9 bits (69), Expect = 0.21 Identities = 13/30 (43%), Positives = 22/30 (73%), Gaps = 1/30 (3%) Query: 202 FLQLLDGLDYLH-GQGVVHKDIKPGNLLLT 230 F ++L+G+ YLH +VH+D+KP N+ L+ Sbjct: 471 FARILEGVLYLHDAMHLVHRDLKPRNIFLS 500 >SPAC12B10.14c |ppk2||serine/threonine protein kinase Ppk2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 665 Score = 29.1 bits (62), Expect = 1.4 Identities = 23/98 (23%), Positives = 41/98 (41%), Gaps = 3/98 (3%) Query: 143 EIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYF 202 E+Q L L HKN+I + + ++ V E+ + P F + Sbjct: 433 ELQRLSGLSHKNLIRYNESFWY--LNNIWSVFEY-KDPSTKLSALIPKYFFSELNIASIC 489 Query: 203 LQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDF 240 ++ GL +LH G+ H ++ + LT LKI ++ Sbjct: 490 YEISSGLAFLHNSGIAHHNLTTECIYLTKSSCLKIGNY 527 >SPAC227.04 |||autophagy C terminal domain family protein|Schizosaccharomyces pombe|chr 1|||Manual Length = 179 Score = 27.1 bits (57), Expect = 5.8 Identities = 14/41 (34%), Positives = 20/41 (48%) Query: 349 IRRHAWVQATPPFEPGEKLVNPRSRRSDELHTSTVIPYLVE 389 I HAW++ +P FE + P + SD L I L+E Sbjct: 63 ITMHAWIRDSPSFEVPQFFFQPYANGSDPLTKMEQIFELLE 103 >SPBC577.09 |||ERCC-8 homolog |Schizosaccharomyces pombe|chr 2|||Manual Length = 404 Score = 26.6 bits (56), Expect = 7.7 Identities = 17/60 (28%), Positives = 24/60 (40%) Query: 230 TLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVT 289 + D TLK+ D + F+ ED+ Y+ SP IA S D+ S T Sbjct: 123 SFDHTLKVWDVSTLQEAYTFTMEDMIYSHAWSPIASHCLIATAYRSSSIRLCDMQSGSYT 182 >SPBC21H7.02 |taf10||transcription factor TFIID complex subunit Taf10 |Schizosaccharomyces pombe|chr 2|||Manual Length = 215 Score = 26.6 bits (56), Expect = 7.7 Identities = 16/58 (27%), Positives = 29/58 (50%) Query: 10 SSSESLPDGDNVEYEISNVIAAQESDDNFMLDGSPELHSVTWLDDEQIEDLDLNLEQT 67 +SS +LP GDN+ A ++D+ D S E H ++ + +E D+ ++T Sbjct: 35 TSSTNLPTGDNLAPMSVESPAHLNNEDSPKSDDSRERHGSNYVIEPHLELRDMAKDKT 92 Database: spombe Posted date: Oct 3, 2007 3:31 PM Number of letters in database: 2,362,478 Number of sequences in database: 5004 Lambda K H 0.318 0.136 0.406 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 2,087,560 Number of Sequences: 5004 Number of extensions: 83340 Number of successful extensions: 457 Number of sequences better than 10.0: 108 Number of HSP's better than 10.0 without gapping: 103 Number of HSP's successfully gapped in prelim test: 5 Number of HSP's that attempted gapping in prelim test: 189 Number of HSP's gapped (non-prelim): 141 length of query: 484 length of database: 2,362,478 effective HSP length: 75 effective length of query: 409 effective length of database: 1,987,178 effective search space: 812755802 effective search space used: 812755802 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits) S2: 56 (26.6 bits)
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