Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000420-TA|BGIBMGA000420-PA|IPR000719|Protein kinase,
IPR011009|Protein kinase-like, IPR008271|Serine/threonine protein
kinase, active site, IPR002290|Serine/threonine protein kinase
(484 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U63333-1|AAB05809.1| 433|Homo sapiens serine/threonine protein ... 389 e-107
BC019334-1|AAH19334.1| 433|Homo sapiens serine/threonine kinase... 389 e-107
BC007981-1|AAH07981.1| 433|Homo sapiens serine/threonine kinase... 389 e-107
AF217978-1|AAG17221.1| 433|Homo sapiens unknown protein. 389 e-107
AF055327-1|AAC15742.1| 433|Homo sapiens Peutz-Jeghers syndrome ... 389 e-107
AF035625-1|AAC39527.1| 433|Homo sapiens serine threonine kinase... 389 e-107
AF032986-1|AAB97833.1| 433|Homo sapiens serine threonine kinase... 389 e-107
AB209553-1|BAD92790.1| 337|Homo sapiens serine/threonine protei... 365 e-100
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 144 8e-34
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 142 2e-33
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 141 6e-33
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 141 6e-33
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 141 6e-33
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 141 6e-33
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 140 8e-33
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 139 2e-32
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 139 2e-32
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 138 5e-32
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 136 1e-31
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 136 1e-31
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 136 1e-31
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 136 1e-31
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 136 1e-31
AJ844634-1|CAH59749.2| 84|Homo sapiens serine/threonine kinase... 134 5e-31
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 134 9e-31
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 134 9e-31
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 134 9e-31
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 134 9e-31
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 132 3e-30
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 132 3e-30
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 131 6e-30
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 131 6e-30
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 131 6e-30
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 131 6e-30
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 129 2e-29
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 129 2e-29
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 129 2e-29
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 129 2e-29
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 129 2e-29
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 129 2e-29
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 129 2e-29
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 129 2e-29
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 128 3e-29
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 128 4e-29
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 128 4e-29
BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine ... 128 6e-29
AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein. 128 6e-29
AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine ... 128 6e-29
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 128 6e-29
AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific serine/... 128 6e-29
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 127 8e-29
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 127 8e-29
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 127 8e-29
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 127 8e-29
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 127 8e-29
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 127 8e-29
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 127 8e-29
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 127 8e-29
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 127 8e-29
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 126 2e-28
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 126 2e-28
BC026060-1|AAH26060.1| 541|Homo sapiens calcium/calmodulin-depe... 126 2e-28
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 126 2e-28
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 126 2e-28
AF321402-1|AAK91829.1| 588|Homo sapiens Ca2+/calmodulin-depende... 126 2e-28
AF321401-1|AAK91830.1| 533|Homo sapiens Ca2+/calmodulin-depende... 126 2e-28
AF321387-1|AAL37217.1| 541|Homo sapiens CaMKK beta 1 isoform pr... 126 2e-28
AF287631-1|AAK64601.1| 533|Homo sapiens calcium/calmodulin-depe... 126 2e-28
AF287630-1|AAK64600.1| 588|Homo sapiens calcium/calmodulin-depe... 126 2e-28
AF101264-1|AAD04566.1| 417|Homo sapiens Ca2+/calmodulin-depende... 126 2e-28
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 126 2e-28
AB081336-1|BAC19840.1| 541|Homo sapiens Ca2+/calmodulin-depende... 126 2e-28
AB018330-1|BAA34507.2| 557|Homo sapiens KIAA0787 protein protein. 126 2e-28
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 126 2e-28
AF140507-1|AAD31507.1| 588|Homo sapiens Ca2+/calmodulin-depende... 126 2e-28
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 124 5e-28
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 124 5e-28
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 124 5e-28
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 124 5e-28
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 124 9e-28
BC043487-1|AAH43487.1| 505|Homo sapiens calcium/calmodulin-depe... 123 1e-27
AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein pro... 123 1e-27
AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein pro... 123 1e-27
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 122 3e-27
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 121 5e-27
AF321388-1|AAL37218.1| 498|Homo sapiens CaMKK beta 1 isoform pr... 118 5e-26
AF321386-1|AAL37216.1| 545|Homo sapiens CaMKK beta 1 isoform pr... 118 5e-26
AF321385-1|AAL37215.1| 490|Homo sapiens CaMKK beta 2 isoform pr... 118 5e-26
AB081337-1|BAC19841.1| 498|Homo sapiens Ca2+/calmodulin-depende... 118 5e-26
AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protei... 117 8e-26
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 116 2e-25
BC000318-1|AAH00318.2| 266|Homo sapiens CAMKK2 protein protein. 116 2e-25
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 116 2e-25
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 115 3e-25
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 115 3e-25
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 115 3e-25
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 115 3e-25
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 115 3e-25
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 115 3e-25
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 115 3e-25
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 115 3e-25
X66357-1|CAA47001.1| 305|Homo sapiens serine/threonine protein ... 115 4e-25
AY789470-1|AAV40830.1| 305|Homo sapiens cyclin-dependent kinase... 115 4e-25
U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase pr... 114 6e-25
BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine ... 114 7e-25
AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protei... 114 7e-25
X66364-1|CAA47007.1| 292|Homo sapiens serine/threonine protein ... 113 2e-24
BT006680-1|AAP35326.1| 292|Homo sapiens cyclin-dependent kinase... 113 2e-24
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 113 2e-24
BC005115-1|AAH05115.1| 292|Homo sapiens cyclin-dependent kinase... 113 2e-24
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 113 2e-24
AY049778-1|AAL15435.1| 292|Homo sapiens cyclin-dependent kinase... 113 2e-24
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 113 2e-24
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 113 2e-24
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 113 2e-24
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 113 2e-24
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 113 2e-24
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 112 3e-24
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 112 3e-24
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 111 4e-24
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 111 5e-24
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 111 5e-24
BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine ... 111 7e-24
AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific serine/... 111 7e-24
AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine ... 111 7e-24
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 110 9e-24
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 110 1e-23
CR457041-1|CAG33322.1| 292|Homo sapiens CDK5 protein. 110 1e-23
BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H... 110 1e-23
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 110 1e-23
AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase p... 110 1e-23
AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS p... 110 1e-23
X61622-1|CAA43807.1| 298|Homo sapiens CDK2 protein. 109 2e-23
X62071-1|CAA43985.1| 298|Homo sapiens cdk2 protein. 109 2e-23
M68520-1|AAA35667.1| 298|Homo sapiens cdc2-related protein kina... 109 2e-23
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 109 2e-23
BT006821-1|AAP35467.1| 298|Homo sapiens cyclin-dependent kinase... 109 2e-23
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 109 2e-23
BC003065-1|AAH03065.1| 298|Homo sapiens cyclin-dependent kinase... 109 2e-23
AF512553-1|AAM34794.1| 298|Homo sapiens cyclin-dependent kinase... 109 2e-23
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 109 2e-23
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 108 4e-23
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 108 4e-23
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 108 4e-23
BC028587-1|AAH28587.1| 482|Homo sapiens NEK11 protein protein. 108 4e-23
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 108 4e-23
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 108 4e-23
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 108 4e-23
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 108 4e-23
AB071997-1|BAC06351.1| 470|Homo sapiens NIMA-related kinase 11S... 108 4e-23
AB071996-1|BAC06350.1| 645|Homo sapiens NIMA-related kinase 11L... 108 4e-23
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 108 4e-23
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 108 4e-23
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 108 5e-23
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 107 7e-23
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 107 7e-23
BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protei... 107 7e-23
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 107 7e-23
AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein pr... 107 7e-23
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 107 7e-23
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 107 7e-23
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 107 7e-23
AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein. 107 7e-23
AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein DK... 107 7e-23
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 107 7e-23
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 107 9e-23
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 106 2e-22
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 106 2e-22
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 106 2e-22
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 106 2e-22
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 106 2e-22
AL157760-2|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 106 2e-22
AL157760-1|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 106 2e-22
AL157694-2|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 106 2e-22
AL157694-1|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 106 2e-22
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 106 2e-22
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 106 2e-22
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 104 6e-22
AL834322-1|CAD38990.1| 365|Homo sapiens hypothetical protein pr... 104 6e-22
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 104 6e-22
AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule affinit... 104 8e-22
AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein. 104 8e-22
BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protei... 103 1e-21
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 103 1e-21
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 103 1e-21
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 103 1e-21
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 103 1e-21
AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protei... 103 1e-21
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 103 1e-21
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 103 1e-21
BC031647-1|AAH31647.1| 520|Homo sapiens calcium/calmodulin-depe... 103 1e-21
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 103 1e-21
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 103 1e-21
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 103 1e-21
Y00272-1|CAA68376.1| 297|Homo sapiens protein ( Human cell cycl... 103 2e-21
X05360-1|CAA28963.1| 297|Homo sapiens protein ( Human CDC2 gene... 103 2e-21
BT007004-1|AAP35650.1| 297|Homo sapiens cell division cycle 2, ... 103 2e-21
BC107750-1|AAI07751.1| 225|Homo sapiens CDC2 protein protein. 103 2e-21
BC014563-1|AAH14563.1| 297|Homo sapiens cell division cycle 2, ... 103 2e-21
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 103 2e-21
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 103 2e-21
AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens ... 103 2e-21
AF512554-1|AAM34793.1| 297|Homo sapiens cell division cycle 2, ... 103 2e-21
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 102 2e-21
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 102 2e-21
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 102 2e-21
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 102 2e-21
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 102 2e-21
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 102 2e-21
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 102 2e-21
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 102 2e-21
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 102 2e-21
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 102 2e-21
AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related prot... 102 2e-21
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 102 2e-21
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 102 3e-21
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 101 4e-21
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 101 4e-21
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 101 4e-21
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 101 6e-21
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 101 6e-21
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 101 6e-21
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 101 6e-21
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 101 6e-21
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 101 6e-21
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 101 7e-21
L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine ... 100 1e-20
BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein. 100 1e-20
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 100 1e-20
X66363-1|CAA47006.1| 496|Homo sapiens serine/threonine protein ... 99 2e-20
BT007299-1|AAP35963.1| 472|Homo sapiens PCTAIRE-motif protein k... 99 2e-20
BT006827-1|AAP35473.1| 496|Homo sapiens PCTAIRE protein kinase ... 99 2e-20
BC015607-1|AAH15607.1| 496|Homo sapiens PCTAIRE protein kinase ... 99 2e-20
BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for IM... 99 2e-20
BC011526-1|AAH11526.1| 472|Homo sapiens PCTAIRE protein kinase ... 99 2e-20
BC009852-1|AAH09852.2| 395|Homo sapiens PCTK1 protein protein. 99 2e-20
BC006190-1|AAH06190.1| 448|Homo sapiens PCTK1 protein protein. 99 2e-20
BC001048-1|AAH01048.1| 496|Homo sapiens PCTAIRE protein kinase ... 99 2e-20
AY353238-1|AAR13066.1| 504|Homo sapiens PCTAIRE protein kinase ... 99 2e-20
AY353237-1|AAR13065.1| 474|Homo sapiens PCTAIRE protein kinase ... 99 2e-20
AL357131-4|CAH72012.1| 472|Homo sapiens PCTAIRE protein kinase ... 99 2e-20
AL096791-1|CAD20055.1| 496|Homo sapiens PCTAIRE protein kinase ... 99 2e-20
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 99 2e-20
AB209307-1|BAD92544.1| 436|Homo sapiens PCTAIRE protein kinase ... 99 2e-20
X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein ... 99 3e-20
U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinas... 99 3e-20
CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein. 99 3e-20
BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent kinase... 99 3e-20
BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent kinase... 99 3e-20
BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine ... 99 3e-20
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 99 3e-20
AY679523-1|AAT74623.1| 1512|Homo sapiens cell division cycle 2-l... 99 3e-20
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 99 3e-20
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 99 3e-20
AF362953-1|AAK98531.1| 358|Homo sapiens testis specific serine/... 99 3e-20
AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine ... 99 3e-20
L25676-1|AAA35668.1| 372|Homo sapiens CDC2-related kinase protein. 99 4e-20
BC117311-1|AAI17312.1| 898|Homo sapiens CASK protein protein. 99 4e-20
BC001968-1|AAH01968.1| 372|Homo sapiens cyclin-dependent kinase... 99 4e-20
AY705392-1|AAU10527.1| 921|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle prefere... 99 4e-20
AL627402-6|CAH71241.1| 590|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL627402-5|CAH71238.1| 897|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL627402-4|CAH71237.1| 909|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL627402-3|CAH71240.1| 926|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL627402-2|CAH71239.1| 921|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL603754-6|CAI41638.1| 590|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL603754-5|CAI41635.1| 926|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL603754-4|CAI41636.1| 921|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL603754-3|CAI41637.1| 897|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL603754-2|CAI41634.1| 909|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL445239-7|CAI41096.1| 590|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL445239-6|CAI41093.1| 926|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL445239-5|CAI41094.1| 921|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL445239-4|CAI41095.1| 897|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL445239-3|CAI41092.1| 909|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL353691-7|CAI42248.1| 590|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL353691-6|CAI42245.1| 926|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL353691-5|CAI42246.1| 921|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL353691-4|CAI42247.1| 897|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL353691-3|CAI42244.1| 909|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL162586-9|CAI39768.1| 372|Homo sapiens cyclin-dependent kinase... 99 4e-20
AL158144-5|CAI42766.1| 590|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL158144-4|CAI42763.1| 926|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL158144-3|CAI42764.1| 921|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL158144-2|CAI42765.1| 897|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AL158144-1|CAI42762.1| 909|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AF517840-1|AAM54039.1| 372|Homo sapiens cyclin-dependent kinase... 99 4e-20
AF035582-1|AAB88198.1| 897|Homo sapiens CASK protein. 99 4e-20
AF032119-1|AAB88125.1| 921|Homo sapiens hCASK protein. 99 4e-20
AB208859-1|BAD92096.1| 917|Homo sapiens calcium/calmodulin-depe... 99 4e-20
AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein. 99 4e-20
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 98 5e-20
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 98 5e-20
U23460-1|AAC99802.1| 664|Homo sapiens proline rich calmodulin-d... 98 5e-20
BC019070-1|AAH19070.1| 503|Homo sapiens calcium/calmodulin-depe... 98 5e-20
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 98 5e-20
AK222703-1|BAD96423.1| 542|Homo sapiens calcium/calmodulin-depe... 98 5e-20
AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin depe... 98 5e-20
AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin depe... 98 5e-20
AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin depe... 98 5e-20
AF140350-1|AAD42070.1| 449|Homo sapiens calcium/calmodulin-depe... 98 5e-20
AF083419-1|AAD42038.1| 517|Homo sapiens calcium/calmodulin-depe... 98 5e-20
AF081924-1|AAD42037.1| 492|Homo sapiens calcium/calmodulin-depe... 98 5e-20
AF081572-1|AAD42036.1| 503|Homo sapiens calcium/calmodulin-depe... 98 5e-20
AF078803-1|AAD42035.1| 542|Homo sapiens calcium/calmodulin-depe... 98 5e-20
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 98 5e-20
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 98 5e-20
X78342-1|CAA55137.1| 360|Homo sapiens PISSLRE protein. 98 7e-20
D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein. 98 7e-20
BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein. 98 7e-20
BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein. 98 7e-20
BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein. 98 7e-20
BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein. 98 7e-20
AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related serine\/t... 98 7e-20
AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related serine\/t... 98 7e-20
AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related serine\/t... 98 7e-20
AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related serine\/t... 98 7e-20
AJ297710-1|CAC10401.1| 1452|Homo sapiens CDC2L5 protein kinase p... 98 7e-20
AJ297709-1|CAC10400.1| 1512|Homo sapiens CDC2L5 protein kinase p... 98 7e-20
AJ010341-1|CAB37619.1| 360|Homo sapiens cyclin-dependent kinase... 98 7e-20
AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20... 98 7e-20
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 98 7e-20
AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein. 98 7e-20
M80629-1|AAA58424.1| 418|Homo sapiens cdc2-related protein kina... 97 9e-20
BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein. 97 9e-20
Z95152-3|CAB08438.1| 365|Homo sapiens mitogen-activated protein... 97 1e-19
Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-l... 97 1e-19
Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein. 97 1e-19
Y10488-1|CAA71512.1| 365|Homo sapiens stress-activated protein ... 97 1e-19
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 97 1e-19
U93232-1|AAB87639.1| 365|Homo sapiens MAP kinase p38delta protein. 97 1e-19
CR541687-1|CAG46488.1| 365|Homo sapiens MAPK13 protein. 97 1e-19
CR536490-1|CAG38729.1| 365|Homo sapiens MAPK13 protein. 97 1e-19
BT007221-1|AAP35885.1| 365|Homo sapiens mitogen-activated prote... 97 1e-19
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 97 1e-19
BC004428-1|AAH04428.1| 365|Homo sapiens mitogen-activated prote... 97 1e-19
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 97 1e-19
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 97 1e-19
BC001641-1|AAH01641.1| 365|Homo sapiens mitogen-activated prote... 97 1e-19
BC000433-1|AAH00433.1| 365|Homo sapiens mitogen-activated prote... 97 1e-19
AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase... 97 1e-19
AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent kinase... 97 1e-19
AF100546-1|AAF36772.1| 365|Homo sapiens stress-activated protei... 97 1e-19
X66362-1|CAA47005.1| 380|Homo sapiens serine/threonine protein ... 97 2e-19
BC070077-1|AAH70077.1| 968|Homo sapiens serine/threonine kinase... 97 2e-19
AK222922-1|BAD96642.1| 307|Homo sapiens MAPK13 protein (Fragmen... 97 2e-19
AF227198-1|AAF36401.1| 1490|Homo sapiens CrkRS protein. 97 2e-19
AF092535-1|AAD23377.1| 365|Homo sapiens mitogen-activated prote... 97 2e-19
AB020711-1|BAA74927.2| 1535|Homo sapiens KIAA0904 protein protein. 97 2e-19
Y10487-1|CAA71511.1| 367|Homo sapiens stress-activated protein ... 96 2e-19
X80230-1|CAA56516.1| 372|Homo sapiens serine/threonine protein ... 96 2e-19
U66243-1|AAB40118.1| 367|Homo sapiens p38gamma MAP Kinase protein. 96 2e-19
BC015741-1|AAH15741.1| 367|Homo sapiens mitogen-activated prote... 96 2e-19
AL022328-12|CAB51538.1| 367|Homo sapiens mitogen-activated prot... 96 2e-19
AF255306-1|AAF72183.1| 372|Homo sapiens protein kinase CDK9 pro... 96 2e-19
AB015718-1|BAA35073.1| 968|Homo sapiens protein kinase protein. 96 2e-19
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 96 3e-19
BT019903-1|AAV38706.1| 372|Homo sapiens cyclin-dependent kinase... 96 3e-19
AF112472-1|AAD03744.1| 542|Homo sapiens calcium/calmodulin-depe... 96 3e-19
AF112471-1|AAD03743.1| 517|Homo sapiens calcium/calmodulin-depe... 96 3e-19
AF015256-1|AAC51758.1| 365|Homo sapiens p38 mitogen-activated p... 96 3e-19
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 95 4e-19
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 95 4e-19
BC001274-1|AAH01274.1| 324|Homo sapiens CDC2L5 protein protein. 95 4e-19
AY994058-1|AAY44299.1| 254|Homo sapiens extracellular regulated... 95 4e-19
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 95 4e-19
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 95 4e-19
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 95 4e-19
AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens ... 95 4e-19
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 95 4e-19
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 95 4e-19
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 95 4e-19
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 95 4e-19
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 95 4e-19
Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein. 95 5e-19
BC056423-1|AAH56423.1| 214|Homo sapiens ULK3 protein protein. 95 5e-19
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 95 5e-19
BC036117-1|AAH36117.1| 214|Homo sapiens ULK3 protein protein. 95 5e-19
AY065978-1|AAL40897.1| 544|Homo sapiens extracellular signal-re... 95 5e-19
BT007185-1|AAP35849.1| 898|Homo sapiens STE20-like kinase protein. 95 6e-19
BC033005-1|AAH33005.1| 523|Homo sapiens PCTAIRE protein kinase ... 95 6e-19
BC002756-1|AAH02756.1| 898|Homo sapiens TAO kinase 3 protein. 95 6e-19
AY574904-1|AAT81413.1| 510|Homo sapiens regulated in COPD kinas... 95 6e-19
AY574902-1|AAT81411.1| 1215|Homo sapiens regulated in COPD kinas... 95 6e-19
AY574901-1|AAT81410.1| 1328|Homo sapiens regulated in COPD kinas... 95 6e-19
AF263311-1|AAG38501.1| 898|Homo sapiens STE20-like kinase protein. 95 6e-19
AF181985-1|AAF25817.1| 898|Homo sapiens serine/threonine kinase... 95 6e-19
AF179867-1|AAF14559.1| 898|Homo sapiens STE20-like kinase protein. 95 6e-19
AF135158-1|AAG09131.1| 898|Homo sapiens serine kinase protein. 95 6e-19
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 94 9e-19
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 94 9e-19
BC038807-1|AAH38807.1| 349|Homo sapiens ALS2CR7 protein protein. 94 9e-19
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 94 9e-19
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 94 9e-19
AF004709-1|AAC51374.1| 365|Homo sapiens stress-activated protei... 94 9e-19
AC007242-1|AAX93182.1| 301|Homo sapiens unknown protein. 94 9e-19
AB053308-1|BAB69017.1| 384|Homo sapiens ALS2CR7 protein. 94 9e-19
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 94 9e-19
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 94 1e-18
BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related k... 94 1e-18
BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protei... 94 1e-18
BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protei... 94 1e-18
BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protei... 94 1e-18
AL713896-5|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 94 1e-18
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 94 1e-18
AL713896-3|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 94 1e-18
AL713896-2|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 94 1e-18
AL596247-5|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 94 1e-18
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 94 1e-18
AL596247-3|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 94 1e-18
AL596247-2|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 94 1e-18
AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related k... 94 1e-18
AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens ... 94 1e-18
AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens ... 94 1e-18
AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protei... 94 1e-18
AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4 ... 94 1e-18
AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional calcium... 94 1e-18
AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protei... 94 1e-18
L33264-1|AAA60092.2| 314|Homo sapiens CDC2-related protein kina... 93 1e-18
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 93 1e-18
BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein. 93 1e-18
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 93 1e-18
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 93 1e-18
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 93 1e-18
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 93 1e-18
AB209288-1|BAD92525.1| 522|Homo sapiens calcium/calmodulin-depe... 93 1e-18
X79483-1|CAA55984.1| 367|Homo sapiens extracellular signal regu... 93 2e-18
CR542222-1|CAG47018.1| 306|Homo sapiens NEK6 protein. 93 2e-18
BC012761-1|AAH12761.1| 313|Homo sapiens NIMA (never in mitosis ... 93 2e-18
BC004209-1|AAH04209.2| 313|Homo sapiens NEK6 protein protein. 93 2e-18
BC004174-1|AAH04174.2| 313|Homo sapiens NEK6 protein protein. 93 2e-18
BC000101-1|AAH00101.2| 313|Homo sapiens NEK6 protein protein. 93 2e-18
AY847283-1|AAW31760.1| 379|Homo sapiens cyclin-dependent kinase... 93 2e-18
AY845084-1|AAW30008.1| 315|Homo sapiens cyclin-dependent kinase... 93 2e-18
AL162724-9|CAH70254.1| 313|Homo sapiens NIMA (never in mitosis ... 93 2e-18
AL162724-2|CAH70247.1| 347|Homo sapiens NIMA (never in mitosis ... 93 2e-18
AL137846-13|CAI10883.1| 313|Homo sapiens NIMA (never in mitosis... 93 2e-18
AL137846-6|CAI10876.1| 347|Homo sapiens NIMA (never in mitosis ... 93 2e-18
AF087909-1|AAG13417.1| 338|Homo sapiens NIMA-related kinase 6 p... 93 2e-18
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 93 2e-18
AB026289-1|BAA85045.1| 306|Homo sapiens protein kinase SID6-151... 93 2e-18
BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein. 93 3e-18
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 93 3e-18
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 92 3e-18
Y13120-1|CAA73587.1| 346|Homo sapiens serine/threonine protein ... 92 3e-18
X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase... 92 3e-18
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 92 3e-18
X79193-1|CAA55785.1| 346|Homo sapiens MO15/CDK-activating kinas... 92 3e-18
X77743-1|CAA54793.1| 346|Homo sapiens CDK activating kinase pro... 92 3e-18
X77303-1|CAA54508.1| 346|Homo sapiens Cdk-activating kinase pro... 92 3e-18
X66360-1|CAA47004.1| 523|Homo sapiens serine/threonine protein ... 92 3e-18
L20320-1|AAA36657.1| 346|Homo sapiens protein serine/threonine ... 92 3e-18
BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein. 92 3e-18
BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein. 92 3e-18
BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein. 92 3e-18
BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein. 92 3e-18
BC005298-1|AAH05298.1| 346|Homo sapiens cyclin-dependent kinase... 92 3e-18
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 92 3e-18
BC000834-1|AAH00834.1| 346|Homo sapiens cyclin-dependent kinase... 92 3e-18
AY987011-1|AAX88806.1| 489|Homo sapiens calcium/calmodulin-depe... 92 3e-18
AY130859-1|AAM77799.1| 346|Homo sapiens cyclin-dependent kinase... 92 3e-18
AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated prote... 92 3e-18
AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated prote... 92 3e-18
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 92 3e-18
AF239798-1|AAF63496.1| 619|Homo sapiens protein kinase MEKK2b p... 92 3e-18
AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated prote... 92 3e-18
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 92 3e-18
AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated prote... 92 3e-18
AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis signal-regula... 92 3e-18
CR457091-1|CAG33372.1| 306|Homo sapiens NEK6 protein. 92 5e-18
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 92 5e-18
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 92 5e-18
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 91 6e-18
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 91 6e-18
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 91 6e-18
BC000281-1|AAH00281.2| 283|Homo sapiens PCTK3 protein protein. 91 6e-18
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 91 6e-18
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 91 6e-18
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 91 6e-18
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 91 6e-18
AK075004-1|BAC11348.1| 423|Homo sapiens protein ( Homo sapiens ... 91 6e-18
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 91 6e-18
AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3 pro... 91 6e-18
AB062450-1|BAB85632.1| 302|Homo sapiens NEK7 protein. 91 6e-18
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 91 8e-18
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 91 8e-18
AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens ... 91 8e-18
AC110926-2|AAY15070.1| 270|Homo sapiens unknown protein. 91 8e-18
AB208963-1|BAD92200.1| 621|Homo sapiens Protein kinase MEKK2b v... 91 8e-18
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 91 1e-17
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 91 1e-17
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 91 1e-17
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 91 1e-17
AF415197-1|AAM33514.1| 566|Homo sapiens calcium/calmodulin-depe... 91 1e-17
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 91 1e-17
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 91 1e-17
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 91 1e-17
Z11696-1|CAA77754.1| 355|Homo sapiens 44kDa protein kinase prot... 90 1e-17
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 90 1e-17
>U63333-1|AAB05809.1| 433|Homo sapiens serine/threonine protein
kinase protein.
Length = 433
Score = 389 bits (958), Expect = e-107
Identities = 184/326 (56%), Positives = 231/326 (70%), Gaps = 1/326 (0%)
Query: 72 HRVDSADIIYRSRKKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXX 131
HR+DS ++IY+ R+K+ K++GKY+MGD+LGEGSYGKVKE+LDS++LCRRAV
Sbjct: 27 HRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLR 86
Query: 132 XXPNGEQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGK 191
PNGE NV++EIQLLR LRHKNVI+LVDV+YN+EKQKMY+VME+CV +Q+ML+S P K
Sbjct: 87 RIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEK 146
Query: 192 KFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQ 251
+FP QAH YF QL+DGL+YLH QG+VHKDIKPGNLLLT TLKI+D GVAEAL F+
Sbjct: 147 RFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAA 206
Query: 252 EDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEA 311
+D C T QGSPAFQPPEIANG + FSG KVDIWS+GVTLYN+TTG YPFEGDN+Y+L E
Sbjct: 207 DDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFEN 266
Query: 312 ISRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPR 371
I + ML +P R ++ +IR+H+W + P + P
Sbjct: 267 IGKGSYAIPGDCGPPLSDLLKG-MLEYEPAKRFSIRQIRQHSWFRKKHPPAEAPVPIPPS 325
Query: 372 SRRSDELHTSTVIPYLVERHYASAQE 397
D + TV+PYL + H A E
Sbjct: 326 PDTKDRWRSMTVVPYLEDLHGADEDE 351
>BC019334-1|AAH19334.1| 433|Homo sapiens serine/threonine kinase 11
protein.
Length = 433
Score = 389 bits (958), Expect = e-107
Identities = 184/326 (56%), Positives = 231/326 (70%), Gaps = 1/326 (0%)
Query: 72 HRVDSADIIYRSRKKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXX 131
HR+DS ++IY+ R+K+ K++GKY+MGD+LGEGSYGKVKE+LDS++LCRRAV
Sbjct: 27 HRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLR 86
Query: 132 XXPNGEQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGK 191
PNGE NV++EIQLLR LRHKNVI+LVDV+YN+EKQKMY+VME+CV +Q+ML+S P K
Sbjct: 87 RIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEK 146
Query: 192 KFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQ 251
+FP QAH YF QL+DGL+YLH QG+VHKDIKPGNLLLT TLKI+D GVAEAL F+
Sbjct: 147 RFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAA 206
Query: 252 EDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEA 311
+D C T QGSPAFQPPEIANG + FSG KVDIWS+GVTLYN+TTG YPFEGDN+Y+L E
Sbjct: 207 DDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFEN 266
Query: 312 ISRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPR 371
I + ML +P R ++ +IR+H+W + P + P
Sbjct: 267 IGKGSYAIPGDCGPPLSDLLKG-MLEYEPAKRFSIRQIRQHSWFRKKHPPAEAPVPIPPS 325
Query: 372 SRRSDELHTSTVIPYLVERHYASAQE 397
D + TV+PYL + H A E
Sbjct: 326 PDTKDRWRSMTVVPYLEDLHGADEDE 351
>BC007981-1|AAH07981.1| 433|Homo sapiens serine/threonine kinase 11
protein.
Length = 433
Score = 389 bits (958), Expect = e-107
Identities = 184/326 (56%), Positives = 231/326 (70%), Gaps = 1/326 (0%)
Query: 72 HRVDSADIIYRSRKKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXX 131
HR+DS ++IY+ R+K+ K++GKY+MGD+LGEGSYGKVKE+LDS++LCRRAV
Sbjct: 27 HRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLR 86
Query: 132 XXPNGEQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGK 191
PNGE NV++EIQLLR LRHKNVI+LVDV+YN+EKQKMY+VME+CV +Q+ML+S P K
Sbjct: 87 RIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEK 146
Query: 192 KFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQ 251
+FP QAH YF QL+DGL+YLH QG+VHKDIKPGNLLLT TLKI+D GVAEAL F+
Sbjct: 147 RFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAA 206
Query: 252 EDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEA 311
+D C T QGSPAFQPPEIANG + FSG KVDIWS+GVTLYN+TTG YPFEGDN+Y+L E
Sbjct: 207 DDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFEN 266
Query: 312 ISRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPR 371
I + ML +P R ++ +IR+H+W + P + P
Sbjct: 267 IGKGSYAIPGDCGPPLSDLLKG-MLEYEPAKRFSIRQIRQHSWFRKKHPPAEAPVPIPPS 325
Query: 372 SRRSDELHTSTVIPYLVERHYASAQE 397
D + TV+PYL + H A E
Sbjct: 326 PDTKDRWRSMTVVPYLEDLHGADEDE 351
>AF217978-1|AAG17221.1| 433|Homo sapiens unknown protein.
Length = 433
Score = 389 bits (958), Expect = e-107
Identities = 184/326 (56%), Positives = 231/326 (70%), Gaps = 1/326 (0%)
Query: 72 HRVDSADIIYRSRKKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXX 131
HR+DS ++IY+ R+K+ K++GKY+MGD+LGEGSYGKVKE+LDS++LCRRAV
Sbjct: 27 HRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLR 86
Query: 132 XXPNGEQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGK 191
PNGE NV++EIQLLR LRHKNVI+LVDV+YN+EKQKMY+VME+CV +Q+ML+S P K
Sbjct: 87 RIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEK 146
Query: 192 KFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQ 251
+FP QAH YF QL+DGL+YLH QG+VHKDIKPGNLLLT TLKI+D GVAEAL F+
Sbjct: 147 RFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAA 206
Query: 252 EDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEA 311
+D C T QGSPAFQPPEIANG + FSG KVDIWS+GVTLYN+TTG YPFEGDN+Y+L E
Sbjct: 207 DDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFEN 266
Query: 312 ISRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPR 371
I + ML +P R ++ +IR+H+W + P + P
Sbjct: 267 IGKGSYAIPGDCGPPLSDLLKG-MLEYEPAKRFSIRQIRQHSWFRKKHPPAEAPVPIPPS 325
Query: 372 SRRSDELHTSTVIPYLVERHYASAQE 397
D + TV+PYL + H A E
Sbjct: 326 PDTKDRWRSMTVVPYLEDLHGADEDE 351
>AF055327-1|AAC15742.1| 433|Homo sapiens Peutz-Jeghers syndrome
protein protein.
Length = 433
Score = 389 bits (958), Expect = e-107
Identities = 184/326 (56%), Positives = 231/326 (70%), Gaps = 1/326 (0%)
Query: 72 HRVDSADIIYRSRKKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXX 131
HR+DS ++IY+ R+K+ K++GKY+MGD+LGEGSYGKVKE+LDS++LCRRAV
Sbjct: 27 HRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLR 86
Query: 132 XXPNGEQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGK 191
PNGE NV++EIQLLR LRHKNVI+LVDV+YN+EKQKMY+VME+CV +Q+ML+S P K
Sbjct: 87 RIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEK 146
Query: 192 KFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQ 251
+FP QAH YF QL+DGL+YLH QG+VHKDIKPGNLLLT TLKI+D GVAEAL F+
Sbjct: 147 RFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAA 206
Query: 252 EDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEA 311
+D C T QGSPAFQPPEIANG + FSG KVDIWS+GVTLYN+TTG YPFEGDN+Y+L E
Sbjct: 207 DDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFEN 266
Query: 312 ISRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPR 371
I + ML +P R ++ +IR+H+W + P + P
Sbjct: 267 IGKGSYAIPGDCGPPLSDLLKG-MLEYEPAKRFSIRQIRQHSWFRKKHPPAEAPVPIPPS 325
Query: 372 SRRSDELHTSTVIPYLVERHYASAQE 397
D + TV+PYL + H A E
Sbjct: 326 PDTKDRWRSMTVVPYLEDLHGADEDE 351
>AF035625-1|AAC39527.1| 433|Homo sapiens serine threonine kinase 11
protein.
Length = 433
Score = 389 bits (958), Expect = e-107
Identities = 184/326 (56%), Positives = 231/326 (70%), Gaps = 1/326 (0%)
Query: 72 HRVDSADIIYRSRKKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXX 131
HR+DS ++IY+ R+K+ K++GKY+MGD+LGEGSYGKVKE+LDS++LCRRAV
Sbjct: 27 HRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLR 86
Query: 132 XXPNGEQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGK 191
PNGE NV++EIQLLR LRHKNVI+LVDV+YN+EKQKMY+VME+CV +Q+ML+S P K
Sbjct: 87 RIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEK 146
Query: 192 KFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQ 251
+FP QAH YF QL+DGL+YLH QG+VHKDIKPGNLLLT TLKI+D GVAEAL F+
Sbjct: 147 RFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAA 206
Query: 252 EDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEA 311
+D C T QGSPAFQPPEIANG + FSG KVDIWS+GVTLYN+TTG YPFEGDN+Y+L E
Sbjct: 207 DDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFEN 266
Query: 312 ISRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPR 371
I + ML +P R ++ +IR+H+W + P + P
Sbjct: 267 IGKGSYAIPGDCGPPLSDLLKG-MLEYEPAKRFSIRQIRQHSWFRKKHPPAEAPVPIPPS 325
Query: 372 SRRSDELHTSTVIPYLVERHYASAQE 397
D + TV+PYL + H A E
Sbjct: 326 PDTKDRWRSMTVVPYLEDLHGADEDE 351
>AF032986-1|AAB97833.1| 433|Homo sapiens serine threonine kinase 11
protein.
Length = 433
Score = 389 bits (958), Expect = e-107
Identities = 184/326 (56%), Positives = 231/326 (70%), Gaps = 1/326 (0%)
Query: 72 HRVDSADIIYRSRKKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXX 131
HR+DS ++IY+ R+K+ K++GKY+MGD+LGEGSYGKVKE+LDS++LCRRAV
Sbjct: 27 HRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLR 86
Query: 132 XXPNGEQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGK 191
PNGE NV++EIQLLR LRHKNVI+LVDV+YN+EKQKMY+VME+CV +Q+ML+S P K
Sbjct: 87 RIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEK 146
Query: 192 KFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQ 251
+FP QAH YF QL+DGL+YLH QG+VHKDIKPGNLLLT TLKI+D GVAEAL F+
Sbjct: 147 RFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAA 206
Query: 252 EDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEA 311
+D C T QGSPAFQPPEIANG + FSG KVDIWS+GVTLYN+TTG YPFEGDN+Y+L E
Sbjct: 207 DDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFEN 266
Query: 312 ISRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPR 371
I + ML +P R ++ +IR+H+W + P + P
Sbjct: 267 IGKGSYAIPGDCGPPLSDLLKG-MLEYEPAKRFSIRQIRQHSWFRKKHPPAEAPVPIPPS 325
Query: 372 SRRSDELHTSTVIPYLVERHYASAQE 397
D + TV+PYL + H A E
Sbjct: 326 PDTKDRWRSMTVVPYLEDLHGADEDE 351
>AB209553-1|BAD92790.1| 337|Homo sapiens serine/threonine protein
kinase 11 variant protein.
Length = 337
Score = 365 bits (899), Expect = e-100
Identities = 165/243 (67%), Positives = 201/243 (82%)
Query: 72 HRVDSADIIYRSRKKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXX 131
HR+DS ++IY+ R+K+ K++GKY+MGD+LGEGSYGKVKE+LDS++LCRRAV
Sbjct: 57 HRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLR 116
Query: 132 XXPNGEQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGK 191
PNGE NV++EIQLLR LRHKNVI+LVDV+YN+EKQKMY+VME+CV +Q+ML+S P K
Sbjct: 117 RIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEK 176
Query: 192 KFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQ 251
+FP QAH YF QL+DGL+YLH QG+VHKDIKPGNLLLT TLKI+D GVAEAL F+
Sbjct: 177 RFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAA 236
Query: 252 EDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEA 311
+D C T QGSPAFQPPEIANG + FSG KVDIWS+GVTLYN+TTG YPFEGDN+Y+L E
Sbjct: 237 DDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFEN 296
Query: 312 ISR 314
I +
Sbjct: 297 IGK 299
>BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein.
Length = 550
Score = 144 bits (348), Expect = 8e-34
Identities = 90/271 (33%), Positives = 137/271 (50%), Gaps = 11/271 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y++GD LG G++GKVK + + AV + ++REIQ L++
Sbjct: 15 IGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSL-DVVGKIRREIQNLKLF 73
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
RH ++I+L VI +++VME+ G L D + + ++++ F Q+L G+
Sbjct: 74 RHPHIIKLYQVI--STPSDIFMVMEYVSGGELFDYI--CKNGRLDEKESRRLFQQILSGV 129
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
DY H VVH+D+KP N+LL KI DFG++ +M S + T GSP + PE+
Sbjct: 130 DYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS---NMMSDGEFLRTSCGSPNYAAPEV 186
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
+G ++G +VDIWSSGV LY + G PF+ D+V L + I
Sbjct: 187 ISG-RLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKIC-DGIFYTPQYLNPSVI 244
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPP 360
HML DP R T+ +IR H W + P
Sbjct: 245 SLLKHMLQVDPMKRATIKDIREHEWFKQDLP 275
>AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein
kinase alpha-1 protein.
Length = 550
Score = 142 bits (344), Expect = 2e-33
Identities = 89/271 (32%), Positives = 137/271 (50%), Gaps = 11/271 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y++GD LG G++GKVK + + AV + ++REIQ L++
Sbjct: 15 IGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSL-DVVGKIRREIQNLKLF 73
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
RH ++I+L VI +++VME+ G L D + + ++++ F Q+L G+
Sbjct: 74 RHPHIIKLYQVI--STPSDIFMVMEYVSGGELFDYI--CKNGRLDEKESRRLFQQILSGV 129
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
DY H VVH+D+KP N+LL KI DFG++ +M S + T GSP + PE+
Sbjct: 130 DYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS---NMMSDGEFLRTSCGSPNYAAPEV 186
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
+G ++G +VDIWSSGV LY + G PF+ D+V L + I
Sbjct: 187 ISG-RLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKIC-DGIFYTPQYLNPSVI 244
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPP 360
HML DP R ++ +IR H W + P
Sbjct: 245 SLLKHMLQVDPMKRASIKDIREHEWFKQDLP 275
>BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 141 bits (341), Expect = 6e-33
Identities = 89/271 (32%), Positives = 134/271 (49%), Gaps = 11/271 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G YV+GD LG G++GKVK + + Q + + ++REIQ L++
Sbjct: 13 IGHYVLGDTLGVGTFGKVK-IGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
RH ++I+L VI ++VME+ G L D + + + +A F Q+L +
Sbjct: 72 RHPHIIKLYQVI--STPTDFFMVMEYVSGGELFDYI--CKHGRVEEMEARRLFQQILSAV 127
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
DY H VVH+D+KP N+LL KI DFG++ +M S + T GSP + PE+
Sbjct: 128 DYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS---NMMSDGEFLRTSCGSPNYAAPEV 184
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
+G ++G +VDIWS GV LY + G PF+ ++V L + I R
Sbjct: 185 ISG-RLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKI-RGGVFYIPEYLNRSVA 242
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPP 360
HML DP R T+ +IR H W + P
Sbjct: 243 TLLMHMLQVDPLKRATIKDIREHEWFKQDLP 273
>BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 141 bits (341), Expect = 6e-33
Identities = 89/271 (32%), Positives = 134/271 (49%), Gaps = 11/271 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G YV+GD LG G++GKVK + + Q + + ++REIQ L++
Sbjct: 13 IGHYVLGDTLGVGTFGKVK-IGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
RH ++I+L VI ++VME+ G L D + + + +A F Q+L +
Sbjct: 72 RHPHIIKLYQVI--STPTDFFMVMEYVSGGELFDYI--CKHGRVEEMEARRLFQQILSAV 127
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
DY H VVH+D+KP N+LL KI DFG++ +M S + T GSP + PE+
Sbjct: 128 DYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS---NMMSDGEFLRTSCGSPNYAAPEV 184
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
+G ++G +VDIWS GV LY + G PF+ ++V L + I R
Sbjct: 185 ISG-RLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKI-RGGVFYIPEYLNRSVA 242
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPP 360
HML DP R T+ +IR H W + P
Sbjct: 243 TLLMHMLQVDPLKRATIKDIREHEWFKQDLP 273
>BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 141 bits (341), Expect = 6e-33
Identities = 89/271 (32%), Positives = 134/271 (49%), Gaps = 11/271 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G YV+GD LG G++GKVK + + Q + + ++REIQ L++
Sbjct: 13 IGHYVLGDTLGVGTFGKVK-IGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
RH ++I+L VI ++VME+ G L D + + + +A F Q+L +
Sbjct: 72 RHPHIIKLYQVI--STPTDFFMVMEYVSGGELFDYI--CKHGRVEEMEARRLFQQILSAV 127
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
DY H VVH+D+KP N+LL KI DFG++ +M S + T GSP + PE+
Sbjct: 128 DYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS---NMMSDGEFLRTSCGSPNYAAPEV 184
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
+G ++G +VDIWS GV LY + G PF+ ++V L + I R
Sbjct: 185 ISG-RLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKI-RGGVFYIPEYLNRSVA 242
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPP 360
HML DP R T+ +IR H W + P
Sbjct: 243 TLLMHMLQVDPLKRATIKDIREHEWFKQDLP 273
>AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 141 bits (341), Expect = 6e-33
Identities = 89/271 (32%), Positives = 134/271 (49%), Gaps = 11/271 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G YV+GD LG G++GKVK + + Q + + ++REIQ L++
Sbjct: 13 IGHYVLGDTLGVGTFGKVK-IGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
RH ++I+L VI ++VME+ G L D + + + +A F Q+L +
Sbjct: 72 RHPHIIKLYQVI--STPTDFFMVMEYVSGGELFDYI--CKHGRVEEMEARRLFQQILSAV 127
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
DY H VVH+D+KP N+LL KI DFG++ +M S + T GSP + PE+
Sbjct: 128 DYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS---NMMSDGEFLRTSCGSPNYAAPEV 184
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
+G ++G +VDIWS GV LY + G PF+ ++V L + I R
Sbjct: 185 ISG-RLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKI-RGGVFYIPEYLNRSVA 242
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPP 360
HML DP R T+ +IR H W + P
Sbjct: 243 TLLMHMLQVDPLKRATIKDIREHEWFKQDLP 273
>U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kinase
protein.
Length = 552
Score = 140 bits (340), Expect = 8e-33
Identities = 89/271 (32%), Positives = 134/271 (49%), Gaps = 11/271 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G YV+GD LG G++GKVK + + Q + + ++REIQ L++
Sbjct: 13 IGHYVLGDTLGVGTFGKVK-IGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
RH ++I+L VI ++VME+ G L D + + + +A F Q+L +
Sbjct: 72 RHPHIIKLYQVI--STPTDFFMVMEYVSGGELFDYI--CKHGRVEEMEARRLFQQILSAV 127
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
DY H VVH+D+KP N+LL KI DFG++ +M S + T GSP + PE+
Sbjct: 128 DYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS---NMMSDGEFLRTSCGSPNYTAPEV 184
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
+G ++G +VDIWS GV LY + G PF+ ++V L + I R
Sbjct: 185 ISG-RLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKI-RGGVFYIPEYLNRSVA 242
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPP 360
HML DP R T+ +IR H W + P
Sbjct: 243 TLLMHMLQVDPLKRATIKDIREHEWFKQGLP 273
>EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2
subunit protein.
Length = 552
Score = 139 bits (336), Expect = 2e-32
Identities = 88/271 (32%), Positives = 133/271 (49%), Gaps = 11/271 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G YV+GD LG G++GKV + + Q + + ++REIQ L++
Sbjct: 13 IGHYVLGDTLGVGTFGKVN-IGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
RH ++I+L VI ++VME+ G L D + + + +A F Q+L +
Sbjct: 72 RHPHIIKLYQVI--STPTDFFMVMEYVSGGELFDYI--CKHGRVEEMEARRLFQQILSAV 127
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
DY H VVH+D+KP N+LL KI DFG++ +M S + T GSP + PE+
Sbjct: 128 DYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS---NMMSDGEFLRTSCGSPNYAAPEV 184
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
+G ++G +VDIWS GV LY + G PF+ ++V L + I R
Sbjct: 185 ISG-RLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKI-RGGVFYIPEYLNRSVA 242
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPP 360
HML DP R T+ +IR H W + P
Sbjct: 243 TLLMHMLQVDPLKRATIKDIREHEWFKQDLP 273
>BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase,
AMP-activated, alpha 1 catalytic subunit protein.
Length = 574
Score = 139 bits (336), Expect = 2e-32
Identities = 92/284 (32%), Positives = 142/284 (50%), Gaps = 22/284 (7%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y++GD LG G++GKVK + + AV + ++REIQ L++
Sbjct: 24 IGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSL-DVVGKIRREIQNLKLF 82
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG------VLQDMLESS-PG-------KKFPQR 196
RH ++I+L VI +++VME+ G + ++ +S PG K+ ++
Sbjct: 83 RHPHIIKLYQVI--STPSDIFMVMEYVSGGELFDYICKNGRKSDVPGVVKTGSTKELDEK 140
Query: 197 QAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICY 256
++ F Q+L G+DY H VVH+D+KP N+LL KI DFG++ +M S +
Sbjct: 141 ESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS---NMMSDGEFLR 197
Query: 257 TGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXX 316
T GSP + PE+ +G ++G +VDIWSSGV LY + G PF+ D+V L + I
Sbjct: 198 TSCGSPNYAAPEVISG-RLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKIC-DG 255
Query: 317 XXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQATPP 360
HML DP R T+ +IR H W + P
Sbjct: 256 IFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLP 299
>AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threonine
protein kinase MAK-V protein.
Length = 714
Score = 138 bits (333), Expect = 5e-32
Identities = 84/272 (30%), Positives = 137/272 (50%), Gaps = 12/272 (4%)
Query: 89 KMVGKYVMGD-VLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLL 147
K VG Y++G LGEGS+ KV+E L + + A+ +N++RE Q+
Sbjct: 56 KRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQ 115
Query: 148 RILRHKNVIELVDVIYNDEKQKMYLVMEFCVG--VLQDMLESSPGKKFPQRQAHDYFLQL 205
+++RH N+ +L+D++ + + YLVME C G ++ + E K+ + +A Y QL
Sbjct: 116 QMIRHPNITQLLDIL--ETENSYYLVMELCPGGNLMHKIYEK---KRLEESEARRYIRQL 170
Query: 206 LDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQ 265
+ +++LH GVVH+D+K NLLL D +K+ DFG++ + D T GSPA+
Sbjct: 171 ISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYA 230
Query: 266 PPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPF--EGDNVYRLLEAISRXXXXXXXXX 323
PE+ A + G K+D+WS GV +Y M TG PF E ++ L + +
Sbjct: 231 APELL--ARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQ 288
Query: 324 XXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+L DP RP + + + W+
Sbjct: 289 LSTGAISFLRSLLEPDPVKRPNIQQALANRWL 320
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 136 bits (330), Expect = 1e-31
Identities = 85/288 (29%), Positives = 143/288 (49%), Gaps = 12/288 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ KVK L L R V P Q + RE+++++IL
Sbjct: 53 IGNYRLLKTIGKGNFAKVK--LARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKIL 110
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YL+ME+ G + D L + K +++A F Q++ +
Sbjct: 111 NHPNIVKLFEVI--ETEKTLYLIMEYASGGEVFDYLVAHGRMK--EKEARSKFRQIVSAV 166
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL D +KI DFG + + + D T GSP + PE+
Sbjct: 167 QYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLD---TFCGSPPYAAPEL 223
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +++ G +VD+WS GV LY + +G PF+G N+ L E + R
Sbjct: 224 FQG-KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLR-GKYRIPFYMSTDCE 281
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRSDE 377
L +P R T+ +I + W+ A + + V P SD+
Sbjct: 282 NLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQ 329
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 136 bits (330), Expect = 1e-31
Identities = 85/288 (29%), Positives = 143/288 (49%), Gaps = 12/288 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ KVK L L R V P Q + RE+++++IL
Sbjct: 53 IGNYRLLKTIGKGNFAKVK--LARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKIL 110
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YL+ME+ G + D L + K +++A F Q++ +
Sbjct: 111 NHPNIVKLFEVI--ETQKTLYLIMEYASGGKVFDYLVAHGRMK--EKEARSKFRQIVSAV 166
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL D +KI DFG + + + D T GSP + PE+
Sbjct: 167 QYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLD---TFCGSPPYAAPEL 223
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +++ G +VD+WS GV LY + +G PF+G N+ L E + R
Sbjct: 224 FQG-KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLR-GKYRIPFYMSTDCE 281
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRSDE 377
L +P R T+ +I + W+ A + + V P SD+
Sbjct: 282 NLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQ 329
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 136 bits (330), Expect = 1e-31
Identities = 85/288 (29%), Positives = 143/288 (49%), Gaps = 12/288 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ KVK L L R V P Q + RE+++++IL
Sbjct: 53 IGNYRLLKTIGKGNFAKVK--LARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKIL 110
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YL+ME+ G + D L + K +++A F Q++ +
Sbjct: 111 NHPNIVKLFEVI--ETEKTLYLIMEYASGGEVFDYLVAHGRMK--EKEARSKFRQIVSAV 166
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL D +KI DFG + + + D T GSP + PE+
Sbjct: 167 QYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLD---TFCGSPPYAAPEL 223
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +++ G +VD+WS GV LY + +G PF+G N+ L E + R
Sbjct: 224 FQG-KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLR-GKYRIPFYMSTDCE 281
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRSDE 377
L +P R T+ +I + W+ A + + V P SD+
Sbjct: 282 NLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQ 329
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 136 bits (330), Expect = 1e-31
Identities = 85/288 (29%), Positives = 143/288 (49%), Gaps = 12/288 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ KVK L L R V P Q + RE+++++IL
Sbjct: 53 IGNYRLLKTIGKGNFAKVK--LARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKIL 110
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YL+ME+ G + D L + K +++A F Q++ +
Sbjct: 111 NHPNIVKLFEVI--ETEKTLYLIMEYASGGKVFDYLVAHGRMK--EKEARSKFRQIVSAV 166
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL D +KI DFG + + + D T GSP + PE+
Sbjct: 167 QYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLD---TFCGSPPYAAPEL 223
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +++ G +VD+WS GV LY + +G PF+G N+ L E + R
Sbjct: 224 FQG-KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLR-GKYRIPFYMSTDCE 281
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRSDE 377
L +P R T+ +I + W+ A + + V P SD+
Sbjct: 282 NLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQ 329
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 136 bits (330), Expect = 1e-31
Identities = 85/288 (29%), Positives = 143/288 (49%), Gaps = 12/288 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ KVK L L R V P Q + RE+++++IL
Sbjct: 53 IGNYRLLKTIGKGNFAKVK--LARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKIL 110
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YL+ME+ G + D L + K +++A F Q++ +
Sbjct: 111 NHPNIVKLFEVI--ETEKTLYLIMEYASGGEVFDYLVAHGRMK--EKEARSKFRQIVSAV 166
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL D +KI DFG + + + D T GSP + PE+
Sbjct: 167 QYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLD---TFCGSPPYAAPEL 223
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +++ G +VD+WS GV LY + +G PF+G N+ L E + R
Sbjct: 224 FQG-KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLR-GKYRIPFYMSTDCE 281
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRSDE 377
L +P R T+ +I + W+ A + + V P SD+
Sbjct: 282 NLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQ 329
>AJ844634-1|CAH59749.2| 84|Homo sapiens serine/threonine kinase 11
protein.
Length = 84
Score = 134 bits (325), Expect = 5e-31
Identities = 61/83 (73%), Positives = 69/83 (83%)
Query: 204 QLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA 263
QL+DGL+YLH QG+VHKDIKPGNLLLT TLKI+D GVAEAL F+ +D C T QGSPA
Sbjct: 2 QLIDGLEYLHSQGIVHKDIKPGNLLLTAGGTLKISDLGVAEALHPFAADDTCRTSQGSPA 61
Query: 264 FQPPEIANGAEQFSGTKVDIWSS 286
FQPPEIANG + FSG KVDIWS+
Sbjct: 62 FQPPEIANGLDTFSGFKVDIWSA 84
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 134 bits (323), Expect = 9e-31
Identities = 98/341 (28%), Positives = 163/341 (47%), Gaps = 18/341 (5%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + +G+G++ KVK L L R V P+ Q + RE+++++ L
Sbjct: 56 VGNYRLLRTIGKGNFAKVK--LARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGL 113
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YLVME+ G + D L S K +++A F Q++ +
Sbjct: 114 NHPNIVKLFEVI--ETEKTLYLVMEYASAGEVFDYLVSHGRMK--EKEARAKFRQIVSAV 169
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL + +KI DFG + + S+ D T GSP + PE+
Sbjct: 170 HYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLD---TFCGSPPYAAPEL 226
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +++ G +VDIWS GV LY + +G PF+G N+ L E + R
Sbjct: 227 FQG-KKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLR-GKYRVPFYMSTDCE 284
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRSDELHTSTVIPYLVE 389
L +P R T+ +I + W+ +E GE+L P + ++ + I +V
Sbjct: 285 SILRRFLVLNPAKRCTLEQIMKDKWINI--GYE-GEEL-KPYTEPEEDFGDTKRIEVMVG 340
Query: 390 RHYA--SAQEYFTERDLRQESDGLRVSGTVRARGWVTAAPG 428
Y +E T + + + + G G APG
Sbjct: 341 MGYTREEIKESLTSQKYNEVTATYLLLGRKTEEGGDRGAPG 381
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 134 bits (323), Expect = 9e-31
Identities = 98/341 (28%), Positives = 163/341 (47%), Gaps = 18/341 (5%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + +G+G++ KVK L L R V P+ Q + RE+++++ L
Sbjct: 56 VGNYRLLRTIGKGNFAKVK--LARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGL 113
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YLVME+ G + D L S K +++A F Q++ +
Sbjct: 114 NHPNIVKLFEVI--ETEKTLYLVMEYASAGEVFDYLVSHGRMK--EKEARAKFRQIVSAV 169
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL + +KI DFG + + S+ D T GSP + PE+
Sbjct: 170 HYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLD---TFCGSPPYAAPEL 226
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +++ G +VDIWS GV LY + +G PF+G N+ L E + R
Sbjct: 227 FQG-KKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLR-GKYRVPFYMSTDCE 284
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRSDELHTSTVIPYLVE 389
L +P R T+ +I + W+ +E GE+L P + ++ + I +V
Sbjct: 285 SILRRFLVLNPAKRCTLEQIMKDKWINI--GYE-GEEL-KPYTEPEEDFGDTKRIEVMVG 340
Query: 390 RHYA--SAQEYFTERDLRQESDGLRVSGTVRARGWVTAAPG 428
Y +E T + + + + G G APG
Sbjct: 341 MGYTREEIKESLTSQKYNEVTATYLLLGRKTEEGGDRGAPG 381
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 134 bits (323), Expect = 9e-31
Identities = 98/341 (28%), Positives = 163/341 (47%), Gaps = 18/341 (5%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + +G+G++ KVK L L R V P+ Q + RE+++++ L
Sbjct: 56 VGNYRLLRTIGKGNFAKVK--LARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGL 113
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YLVME+ G + D L S K +++A F Q++ +
Sbjct: 114 NHPNIVKLFEVI--ETEKTLYLVMEYASAGEVFDYLVSHGRMK--EKEARAKFRQIVSAV 169
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL + +KI DFG + + S+ D T GSP + PE+
Sbjct: 170 HYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLD---TFCGSPPYAAPEL 226
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +++ G +VDIWS GV LY + +G PF+G N+ L E + R
Sbjct: 227 FQG-KKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLR-GKYRVPFYMSTDCE 284
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRSDELHTSTVIPYLVE 389
L +P R T+ +I + W+ +E GE+L P + ++ + I +V
Sbjct: 285 SILRRFLVLNPAKRCTLEQIMKDKWINI--GYE-GEEL-KPYTEPEEDFGDTKRIEVMVG 340
Query: 390 RHYA--SAQEYFTERDLRQESDGLRVSGTVRARGWVTAAPG 428
Y +E T + + + + G G APG
Sbjct: 341 MGYTREEIKESLTSQKYNEVTATYLLLGRKTEEGGDRGAPG 381
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 134 bits (323), Expect = 9e-31
Identities = 98/341 (28%), Positives = 163/341 (47%), Gaps = 18/341 (5%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + +G+G++ KVK L L R V P+ Q + RE+++++ L
Sbjct: 57 VGNYRLLRTIGKGNFAKVK--LARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGL 114
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YLVME+ G + D L S K +++A F Q++ +
Sbjct: 115 NHPNIVKLFEVI--ETEKTLYLVMEYASAGEVFDYLVSHGRMK--EKEARAKFRQIVSAV 170
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL + +KI DFG + + S+ D T GSP + PE+
Sbjct: 171 HYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLD---TFCGSPPYAAPEL 227
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +++ G +VDIWS GV LY + +G PF+G N+ L E + R
Sbjct: 228 FQG-KKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLR-GKYRVPFYMSTDCE 285
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRSDELHTSTVIPYLVE 389
L +P R T+ +I + W+ +E GE+L P + ++ + I +V
Sbjct: 286 SILRRFLVLNPAKRCTLEQIMKDKWINI--GYE-GEEL-KPYTEPEEDFGDTKRIEVMVG 341
Query: 390 RHYA--SAQEYFTERDLRQESDGLRVSGTVRARGWVTAAPG 428
Y +E T + + + + G G APG
Sbjct: 342 MGYTREEIKESLTSQKYNEVTATYLLLGRKTEEGGDRGAPG 382
>AB088047-1|BAC03375.1| 752|Homo sapiens microtubule
affinity-regulating kinase-like1 protein.
Length = 752
Score = 132 bits (318), Expect = 3e-30
Identities = 98/341 (28%), Positives = 162/341 (47%), Gaps = 18/341 (5%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + +G+G+ KVK L L R V P+ Q + RE+++++ L
Sbjct: 56 VGNYRLLRTIGKGNSAKVK--LARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGL 113
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YLVME+ G + D L S K +++A F Q++ +
Sbjct: 114 NHPNIVKLFEVI--ETEKTLYLVMEYASAGEVFDYLVSHGRMK--EKEARAKFRQIVSAV 169
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL + +KI DFG + + S+ D T GSP + PE+
Sbjct: 170 HYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLD---TFCGSPPYAAPEL 226
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +++ G +VDIWS GV LY + +G PF+G N+ L E + R
Sbjct: 227 FQG-KKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLR-GKYRVPFYMSTDCE 284
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRSDELHTSTVIPYLVE 389
L +P R T+ +I + W+ +E GE+L P + ++ + I +V
Sbjct: 285 SILRRFLVLNPAKRCTLEQIMKDKWINI--GYE-GEEL-KPYTEPEEDFGDTKRIEVMVG 340
Query: 390 RHYA--SAQEYFTERDLRQESDGLRVSGTVRARGWVTAAPG 428
Y +E T + + + + G G APG
Sbjct: 341 MGYTREEIKESLTSQKYNEVTATYLLLGRKTEEGGDRGAPG 381
>AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule
affinity-regulating kinase like 1 protein.
Length = 688
Score = 132 bits (318), Expect = 3e-30
Identities = 98/341 (28%), Positives = 162/341 (47%), Gaps = 18/341 (5%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + +G+G+ KVK L L R V P+ Q + RE+++++ L
Sbjct: 56 VGNYRLLRTIGKGNSAKVK--LARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGL 113
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YLVME+ G + D L S K +++A F Q++ +
Sbjct: 114 NHPNIVKLFEVI--ETEKTLYLVMEYASAGEVFDYLVSHGRMK--EKEARAKFRQIVSAV 169
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL + +KI DFG + + S+ D T GSP + PE+
Sbjct: 170 HYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLD---TFCGSPPYAAPEL 226
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +++ G +VDIWS GV LY + +G PF+G N+ L E + R
Sbjct: 227 FQG-KKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLR-GKYRVPFYMSTDCE 284
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRSDELHTSTVIPYLVE 389
L +P R T+ +I + W+ +E GE+L P + ++ + I +V
Sbjct: 285 SILRRFLVLNPAKRCTLEQIMKDKWINI--GYE-GEEL-KPYTEPEEDFGDTKRIEVMVG 340
Query: 390 RHYA--SAQEYFTERDLRQESDGLRVSGTVRARGWVTAAPG 428
Y +E T + + + + G G APG
Sbjct: 341 MGYTREEIKESLTSQKYNEVTATYLLLGRKTEEGGDRGAPG 381
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 131 bits (316), Expect = 6e-30
Identities = 75/225 (33%), Positives = 125/225 (55%), Gaps = 11/225 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ KVK L L R V P Q + RE+++++IL
Sbjct: 57 IGNYRLQKTIGKGNFAKVK--LARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKIL 114
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YLVME+ G + D L + K +++A F Q++ +
Sbjct: 115 NHPNIVKLFEVI--ETEKTLYLVMEYASGGEVFDYLVAHGRMK--EKEARAKFRQIVSAV 170
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL D +KI DFG + + ++ D T GSP + PE+
Sbjct: 171 QYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLD---TFCGSPPYAAPEL 227
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
G +++ G +VD+WS GV LY + +G PF+G N+ L E + R
Sbjct: 228 FQG-KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLR 271
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 131 bits (316), Expect = 6e-30
Identities = 75/225 (33%), Positives = 125/225 (55%), Gaps = 11/225 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ KVK L L R V P Q + RE+++++IL
Sbjct: 57 IGNYRLQKTIGKGNFAKVK--LARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKIL 114
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YLVME+ G + D L + K +++A F Q++ +
Sbjct: 115 NHPNIVKLFEVI--ETEKTLYLVMEYASGGEVFDYLVAHGRMK--EKEARAKFRQIVSAV 170
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL D +KI DFG + + ++ D T GSP + PE+
Sbjct: 171 QYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLD---TFCGSPPYAAPEL 227
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
G +++ G +VD+WS GV LY + +G PF+G N+ L E + R
Sbjct: 228 FQG-KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLR 271
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 131 bits (316), Expect = 6e-30
Identities = 75/225 (33%), Positives = 125/225 (55%), Gaps = 11/225 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ KVK L L R V P Q + RE+++++IL
Sbjct: 57 IGNYRLQKTIGKGNFAKVK--LARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKIL 114
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YLVME+ G + D L + K +++A F Q++ +
Sbjct: 115 NHPNIVKLFEVI--ETEKTLYLVMEYASGGEVFDYLVAHGRMK--EKEARAKFRQIVSAV 170
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL D +KI DFG + + ++ D T GSP + PE+
Sbjct: 171 QYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLD---TFCGSPPYAAPEL 227
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
G +++ G +VD+WS GV LY + +G PF+G N+ L E + R
Sbjct: 228 FQG-KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLR 271
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 131 bits (316), Expect = 6e-30
Identities = 75/225 (33%), Positives = 125/225 (55%), Gaps = 11/225 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ KVK L L R V P Q + RE+++++IL
Sbjct: 57 IGNYRLQKTIGKGNFAKVK--LARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKIL 114
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YLVME+ G + D L + K +++A F Q++ +
Sbjct: 115 NHPNIVKLFEVI--ETEKTLYLVMEYASGGEVFDYLVAHGRMK--EKEARAKFRQIVSAV 170
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL D +KI DFG + + ++ D T GSP + PE+
Sbjct: 171 QYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLD---TFCGSPPYAAPEL 227
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
G +++ G +VD+WS GV LY + +G PF+G N+ L E + R
Sbjct: 228 FQG-KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLR 271
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 129 bits (312), Expect = 2e-29
Identities = 81/295 (27%), Positives = 145/295 (49%), Gaps = 12/295 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ KVK L L + V + Q + RE++++++L
Sbjct: 17 IGNYRLLKTIGKGNFAKVK--LARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVL 74
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YLVME+ G + D L + K +++A F Q++ +
Sbjct: 75 NHPNIVKLFEVI--ETEKTLYLVMEYASGGEVFDYLVAHGRMK--EKEARAKFRQIVSAV 130
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL D +KI DFG + ++ D T GSP + PE+
Sbjct: 131 QYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLD---TFCGSPPYAAPEL 187
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +++ G +VD+WS GV LY + +G PF+G N+ L E + R
Sbjct: 188 FQG-KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCEN 246
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRSDELHTSTVI 384
++ +P+ R T+ +I + W+ + + V P D T ++
Sbjct: 247 LLKKFLI-LNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMV 300
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 129 bits (312), Expect = 2e-29
Identities = 81/295 (27%), Positives = 145/295 (49%), Gaps = 12/295 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ KVK L L + V + Q + RE++++++L
Sbjct: 17 IGNYRLLKTIGKGNFAKVK--LARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVL 74
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YLVME+ G + D L + K +++A F Q++ +
Sbjct: 75 NHPNIVKLFEVI--ETEKTLYLVMEYASGGEVFDYLVAHGRMK--EKEARAKFRQIVSAV 130
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL D +KI DFG + ++ D T GSP + PE+
Sbjct: 131 QYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLD---TFCGSPPYAAPEL 187
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +++ G +VD+WS GV LY + +G PF+G N+ L E + R
Sbjct: 188 FQG-KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCEN 246
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRSDELHTSTVI 384
++ +P+ R T+ +I + W+ + + V P D T ++
Sbjct: 247 LLKKFLI-LNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMV 300
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 129 bits (312), Expect = 2e-29
Identities = 81/295 (27%), Positives = 145/295 (49%), Gaps = 12/295 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ KVK L L + V + Q + RE++++++L
Sbjct: 50 IGNYRLLKTIGKGNFAKVK--LARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVL 107
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YLVME+ G + D L + K +++A F Q++ +
Sbjct: 108 NHPNIVKLFEVI--ETEKTLYLVMEYASGGEVFDYLVAHGRMK--EKEARAKFRQIVSAV 163
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL D +KI DFG + ++ D T GSP + PE+
Sbjct: 164 QYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLD---TFCGSPPYAAPEL 220
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +++ G +VD+WS GV LY + +G PF+G N+ L E + R
Sbjct: 221 FQG-KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCEN 279
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRSDELHTSTVI 384
++ +P+ R T+ +I + W+ + + V P D T ++
Sbjct: 280 LLKKFLI-LNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMV 333
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 129 bits (312), Expect = 2e-29
Identities = 81/295 (27%), Positives = 145/295 (49%), Gaps = 12/295 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ KVK L L + V + Q + RE++++++L
Sbjct: 40 IGNYRLLKTIGKGNFAKVK--LARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVL 97
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YLVME+ G + D L + K +++A F Q++ +
Sbjct: 98 NHPNIVKLFEVI--ETEKTLYLVMEYASGGEVFDYLVAHGRMK--EKEARAKFRQIVSAV 153
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL D +KI DFG + ++ D T GSP + PE+
Sbjct: 154 QYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLD---TFCGSPPYAAPEL 210
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +++ G +VD+WS GV LY + +G PF+G N+ L E + R
Sbjct: 211 FQG-KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCEN 269
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRSDELHTSTVI 384
++ +P+ R T+ +I + W+ + + V P D T ++
Sbjct: 270 LLKKFLI-LNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMV 323
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 129 bits (312), Expect = 2e-29
Identities = 81/295 (27%), Positives = 145/295 (49%), Gaps = 12/295 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ KVK L L + V + Q + RE++++++L
Sbjct: 17 IGNYRLLKTIGKGNFAKVK--LARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVL 74
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YLVME+ G + D L + K +++A F Q++ +
Sbjct: 75 NHPNIVKLFEVI--ETEKTLYLVMEYASGGEVFDYLVAHGRMK--EKEARAKFRQIVSAV 130
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL D +KI DFG + ++ D T GSP + PE+
Sbjct: 131 QYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLD---TFCGSPPYAAPEL 187
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +++ G +VD+WS GV LY + +G PF+G N+ L E + R
Sbjct: 188 FQG-KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCEN 246
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRSDELHTSTVI 384
++ +P+ R T+ +I + W+ + + V P D T ++
Sbjct: 247 LLKKFLI-LNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMV 300
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 129 bits (312), Expect = 2e-29
Identities = 81/295 (27%), Positives = 145/295 (49%), Gaps = 12/295 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ KVK L L + V + Q + RE++++++L
Sbjct: 50 IGNYRLLKTIGKGNFAKVK--LARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVL 107
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H N+++L +VI + ++ +YLVME+ G + D L + K +++A F Q++ +
Sbjct: 108 NHPNIVKLFEVI--ETEKTLYLVMEYASGGEVFDYLVAHGRMK--EKEARAKFRQIVSAV 163
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
Y H + +VH+D+K NLLL D +KI DFG + ++ D T GSP + PE+
Sbjct: 164 QYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLD---TFCGSPPYAAPEL 220
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +++ G +VD+WS GV LY + +G PF+G N+ L E + R
Sbjct: 221 FQG-KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCEN 279
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRSDELHTSTVI 384
++ +P+ R T+ +I + W+ + + V P D T ++
Sbjct: 280 LLKKFLI-LNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMV 333
>AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A
protein.
Length = 696
Score = 129 bits (311), Expect = 2e-29
Identities = 84/265 (31%), Positives = 131/265 (49%), Gaps = 12/265 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + LG+G G VK L + + V + V+REI +L+++
Sbjct: 16 VGPYRLEKTLGKGQTGLVK--LGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLI 73
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H +V++L DV N K+ +YLV+E G L D L G+ P ++A +F Q++ L
Sbjct: 74 EHPHVLKLHDVYEN--KKYLYLVLEHVSGGELFDYLVKK-GRLTP-KEARKFFRQIISAL 129
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
D+ H + H+D+KP NLLL ++I DFG+A + + + T GSP + PE+
Sbjct: 130 DFCHSHSICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEV 186
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G E++ G K D+WS GV L+ + G PF+ DN+ +LLE + R
Sbjct: 187 IRG-EKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQS 245
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAW 354
M+ D R T+ I++H W
Sbjct: 246 LLRG-MIEVDAARRLTLEHIQKHIW 269
>AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 794
Score = 129 bits (311), Expect = 2e-29
Identities = 83/272 (30%), Positives = 136/272 (50%), Gaps = 12/272 (4%)
Query: 84 RKKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQRE 143
R + + VG Y + LG+G G VK L + + V + V+RE
Sbjct: 40 RGRHAQYVGPYRLEKTLGKGQTGLVK--LGVHCITGQKVAIKIVNREKLSESVLMKVERE 97
Query: 144 IQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYF 202
I +L+++ H +V++L DV N K+ +YLV+E G L D L G+ P ++A +F
Sbjct: 98 IAILKLIEHPHVLKLHDVYEN--KKYLYLVLEHVSGGELFDYLVKK-GRLTP-KEARKFF 153
Query: 203 LQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSP 262
Q++ LD+ H + H+D+KP NLLL ++I DFG+A + + + T GSP
Sbjct: 154 RQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSP 210
Query: 263 AFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXX 322
+ PE+ G E++ G + D+WS GV L+ + G PF+ DN+ +LLE + R
Sbjct: 211 HYACPEVIKG-EKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHF 269
Query: 323 XXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAW 354
M+ +P R ++ +I++H W
Sbjct: 270 IPPDCQSLLRG-MIEVEPEKRLSLEQIQKHPW 300
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 128 bits (310), Expect = 3e-29
Identities = 80/265 (30%), Positives = 133/265 (50%), Gaps = 14/265 (5%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQ-NVQREIQLLRILR 151
+Y + + LG+G+YGKVK + S R V + +++REI+++ L
Sbjct: 91 RYELQETLGKGTYGKVKRATERFS--GRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLN 148
Query: 152 HKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDGLD 210
H ++I + +V N K K+ ++ME+ G L D + S ++ +R+ +F Q++ +
Sbjct: 149 HPHIISIYEVFEN--KDKIVIIMEYASKGELYDYI--SERRRLSERETRHFFRQIVSAVH 204
Query: 211 YLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIA 270
Y H GVVH+D+K N+LL + +KI DFG++ +++ ++ T GSP + PEI
Sbjct: 205 YCHKNGVVHRDLKLENILLDDNCNIKIADFGLS---NLYQKDKFLQTFCGSPLYASPEIV 261
Query: 271 NGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXX 330
NG + G +VD W+ GV LY + G PF+G + L+ IS
Sbjct: 262 NG-RPYRGPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQPSDARGLI 320
Query: 331 XXXHMLNRDPTLRPTVHEIRRHAWV 355
M+N P R T+ +I H WV
Sbjct: 321 RWMLMVN--PDRRATIEDIANHWWV 343
>BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein.
Length = 783
Score = 128 bits (309), Expect = 4e-29
Identities = 82/276 (29%), Positives = 135/276 (48%), Gaps = 12/276 (4%)
Query: 85 KKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREI 144
++K VG Y + LG+G++ VK L + + V + + + RE+
Sbjct: 18 QQKPLRVGFYDIERTLGKGNFAVVK--LARHRVTKTQVAIKIIDKTRLDSSNLEKIYREV 75
Query: 145 QLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFL 203
QL+++L H ++I+L V+ + K +Y+V EF G + D L S+ + +A F
Sbjct: 76 QLMKLLNHPHIIKLYQVM--ETKDMLYIVTEFAKNGEMFDYLTSNG--HLSENEARKKFW 131
Query: 204 QLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA 263
Q+L ++Y H +VH+D+K NLLL + +K+ DFG + + + T GSP
Sbjct: 132 QILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFG---NFYKSGEPLSTWCGSPP 188
Query: 264 FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXX 323
+ PE+ G E + G ++DIWS GV LY + G PF+G N+ L + +
Sbjct: 189 YAAPEVFEGKE-YEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLE-GRFRIPFF 246
Query: 324 XXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQATP 359
ML DP R T+ +IR+H W++A P
Sbjct: 247 MSQDCESLIRRMLVVDPARRITIAQIRQHRWMRAEP 282
>AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protein
kinase protein.
Length = 783
Score = 128 bits (309), Expect = 4e-29
Identities = 82/276 (29%), Positives = 135/276 (48%), Gaps = 12/276 (4%)
Query: 85 KKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREI 144
++K VG Y + LG+G++ VK L + + V + + + RE+
Sbjct: 18 QQKPLRVGFYDIERTLGKGNFAVVK--LARHRVTKTQVAIKIIDKTRLDSSNLEKIYREV 75
Query: 145 QLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFL 203
QL+++L H ++I+L V+ + K +Y+V EF G + D L S+ + +A F
Sbjct: 76 QLMKLLNHPHIIKLYQVM--ETKDMLYIVTEFAKNGEMFDYLTSNG--HLSENEARKKFW 131
Query: 204 QLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA 263
Q+L ++Y H +VH+D+K NLLL + +K+ DFG + + + T GSP
Sbjct: 132 QILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFG---NFYKSGEPLSTWCGSPP 188
Query: 264 FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXX 323
+ PE+ G E + G ++DIWS GV LY + G PF+G N+ L + +
Sbjct: 189 YAAPEVFEGKE-YEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLE-GRFRIPFF 246
Query: 324 XXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQATP 359
ML DP R T+ +IR+H W++A P
Sbjct: 247 MSQDCESLIRRMLVVDPARRITIAQIRQHRWMRAEP 282
>BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 128 bits (308), Expect = 6e-29
Identities = 83/267 (31%), Positives = 131/267 (49%), Gaps = 10/267 (3%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y +G +GEG+Y KVKE S+ R+ ++ + RE+Q++R L HK
Sbjct: 10 YQLGKTIGEGTYSKVKEAF-SKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHK 68
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVG--VLQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
N+I++ +++ + + K+ LVME G V +L P P+ +A F Q+++ + Y
Sbjct: 69 NIIQVYEMLESADG-KICLVMELAEGGDVFDCVLNGGP---LPESRAKALFRQMVEAIRY 124
Query: 212 LHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIAN 271
HG GV H+D+K N LL LK+TDFG A+ L S ++ T GS A+ PE+
Sbjct: 125 CHGCGVAHRDLKCENALLQ-GFNLKLTDFGFAKVLPK-SHRELSQTFCGSTAYAAPEVLQ 182
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXX 331
G S K D+WS GV LY M PF+ ++ ++L +
Sbjct: 183 GIPHDS-KKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDL 241
Query: 332 XXHMLNRDPTLRPTVHEIRRHAWVQAT 358
+L D LRP++ E+ H W+ +T
Sbjct: 242 LKRLLEPDMILRPSIEEVSWHPWLAST 268
>AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein.
Length = 268
Score = 128 bits (308), Expect = 6e-29
Identities = 83/267 (31%), Positives = 131/267 (49%), Gaps = 10/267 (3%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y +G +GEG+Y KVKE S+ R+ ++ + RE+Q++R L HK
Sbjct: 10 YQLGKTIGEGTYSKVKEAF-SKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHK 68
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVG--VLQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
N+I++ +++ + + K+ LVME G V +L P P+ +A F Q+++ + Y
Sbjct: 69 NIIQVYEMLESADG-KICLVMELAEGGDVFDCVLNGGP---LPESRAKALFRQMVEAIRY 124
Query: 212 LHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIAN 271
HG GV H+D+K N LL LK+TDFG A+ L S ++ T GS A+ PE+
Sbjct: 125 CHGCGVAHRDLKCENALLQ-GFNLKLTDFGFAKVLPK-SHRELSQTFCGSTAYAAPEVLQ 182
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXX 331
G S K D+WS GV LY M PF+ ++ ++L +
Sbjct: 183 GIPHDS-KKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDL 241
Query: 332 XXHMLNRDPTLRPTVHEIRRHAWVQAT 358
+L D LRP++ E+ H W+ +T
Sbjct: 242 LKRLLEPDMILRPSIEEVSWHPWLAST 268
>AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 128 bits (308), Expect = 6e-29
Identities = 83/267 (31%), Positives = 131/267 (49%), Gaps = 10/267 (3%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y +G +GEG+Y KVKE S+ R+ ++ + RE+Q++R L HK
Sbjct: 10 YQLGKTIGEGTYSKVKEAF-SKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHK 68
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVG--VLQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
N+I++ +++ + + K+ LVME G V +L P P+ +A F Q+++ + Y
Sbjct: 69 NIIQVYEMLESADG-KICLVMELAEGGDVFDCVLNGGP---LPESRAKALFRQMVEAIRY 124
Query: 212 LHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIAN 271
HG GV H+D+K N LL LK+TDFG A+ L S ++ T GS A+ PE+
Sbjct: 125 CHGCGVAHRDLKCENALLQ-GFNLKLTDFGFAKVLPK-SHRELSQTFCGSTAYAAPEVLQ 182
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXX 331
G S K D+WS GV LY M PF+ ++ ++L +
Sbjct: 183 GIPHDS-KKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDL 241
Query: 332 XXHMLNRDPTLRPTVHEIRRHAWVQAT 358
+L D LRP++ E+ H W+ +T
Sbjct: 242 LKRLLEPDMILRPSIEEVSWHPWLAST 268
>AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein.
Length = 764
Score = 128 bits (308), Expect = 6e-29
Identities = 81/270 (30%), Positives = 132/270 (48%), Gaps = 12/270 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + LG+G++ VK L + + V + + + RE+QL+++L
Sbjct: 5 VGFYDIERTLGKGNFAVVK--LARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLL 62
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H ++I+L V+ + K +Y+V EF G + D L S+ + +A F Q+L +
Sbjct: 63 NHPHIIKLYQVM--ETKDMLYIVTEFAKNGEMFDYLTSNG--HLSENEARKKFWQILSAV 118
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
+Y H +VH+D+K NLLL + +K+ DFG + + + T GSP + PE+
Sbjct: 119 EYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFG---NFYKSGEPLSTWCGSPPYAAPEV 175
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G E + G ++DIWS GV LY + G PF+G N+ L + +
Sbjct: 176 FEGKE-YEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLE-GRFRIPFFMSQDCE 233
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATP 359
ML DP R T+ +IR+H W++A P
Sbjct: 234 SLIRRMLVVDPARRITIAQIRQHRWMRAEP 263
>AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific
serine/threonine kinase 3 protein.
Length = 268
Score = 128 bits (308), Expect = 6e-29
Identities = 83/267 (31%), Positives = 131/267 (49%), Gaps = 10/267 (3%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y +G +GEG+Y KVKE S+ R+ ++ + RE+Q++R L HK
Sbjct: 10 YQLGKTIGEGTYSKVKEAF-SKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHK 68
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVG--VLQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
N+I++ +++ + + K+ LVME G V +L P P+ +A F Q+++ + Y
Sbjct: 69 NIIQVYEMLESADG-KICLVMELAEGGDVFDCVLNGGP---LPESRAKALFRQMVEAIRY 124
Query: 212 LHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIAN 271
HG GV H+D+K N LL LK+TDFG A+ L S ++ T GS A+ PE+
Sbjct: 125 CHGCGVAHRDLKCENALLQ-GFNLKLTDFGFAKVLPK-SHRELSQTFCGSTAYAAPEVLQ 182
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXX 331
G S K D+WS GV LY M PF+ ++ ++L +
Sbjct: 183 GIPHDS-KKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDL 241
Query: 332 XXHMLNRDPTLRPTVHEIRRHAWVQAT 358
+L D LRP++ E+ H W+ +T
Sbjct: 242 LKRLLEPDMILRPSIEEVSWHPWLAST 268
>AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B
protein.
Length = 778
Score = 127 bits (307), Expect = 8e-29
Identities = 82/265 (30%), Positives = 133/265 (50%), Gaps = 12/265 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + LG+G G VK L + + V + V+REI +L+++
Sbjct: 31 VGPYRLEKTLGKGQTGLVK--LGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLI 88
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H +V++L DV N K+ +YLV+E G L D L G+ P ++A +F Q++ L
Sbjct: 89 EHPHVLKLHDVYEN--KKYLYLVLEHVSGGELFDYLVKK-GRLTP-KEARKFFRQIVSAL 144
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
D+ H + H+D+KP NLLL ++I DFG+A + + + T GSP + PE+
Sbjct: 145 DFCHSYSICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEV 201
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G E++ G + D+WS GV L+ + G PF+ DN+ +LLE + R
Sbjct: 202 IKG-EKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQS 260
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAW 354
M+ +P R ++ +I++H W
Sbjct: 261 LLRG-MIEVEPEKRLSLEQIQKHPW 284
>AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein.
Length = 778
Score = 127 bits (307), Expect = 8e-29
Identities = 82/265 (30%), Positives = 133/265 (50%), Gaps = 12/265 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + LG+G G VK L + + V + V+REI +L+++
Sbjct: 31 VGPYRLEKTLGKGQTGLVK--LGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLI 88
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H +V++L DV N K+ +YLV+E G L D L G+ P ++A +F Q++ L
Sbjct: 89 EHPHVLKLHDVYEN--KKYLYLVLEHVSGGELFDYLVKK-GRLTP-KEARKFFRQIVSAL 144
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
D+ H + H+D+KP NLLL ++I DFG+A + + + T GSP + PE+
Sbjct: 145 DFCHSYSICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEV 201
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G E++ G + D+WS GV L+ + G PF+ DN+ +LLE + R
Sbjct: 202 IKG-EKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQS 260
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAW 354
M+ +P R ++ +I++H W
Sbjct: 261 LLRG-MIEVEPEKRLSLEQIQKHPW 284
>AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protein
kinase isoform protein.
Length = 668
Score = 127 bits (307), Expect = 8e-29
Identities = 84/265 (31%), Positives = 130/265 (49%), Gaps = 12/265 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + LG+G G VK L + + V + V+REI +L+++
Sbjct: 16 VGPYRLEKTLGKGQTGLVK--LGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLI 73
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H +V++L DV N K+ +YLV+E G L D L G+ P ++A +F Q++ L
Sbjct: 74 EHPHVLKLHDVYEN--KKYLYLVLEHVSGGELFDYLVKK-GRLTP-KEARKFFRQIISAL 129
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
D+ H + H+D+KP NLLL ++I DFG+A + + + T GSP + PE+
Sbjct: 130 DFCHSHSICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEV 186
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G E++ G K D+WS GV L+ + G PF+ DN+ +LLE + R
Sbjct: 187 IRG-EKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQS 245
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAW 354
M D R T+ I++H W
Sbjct: 246 LLRG-MSEVDAARRLTLEHIQKHIW 269
>AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B3 protein.
Length = 674
Score = 127 bits (307), Expect = 8e-29
Identities = 84/265 (31%), Positives = 130/265 (49%), Gaps = 12/265 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + LG+G G VK L + + V + V+REI +L+++
Sbjct: 16 VGPYRLEKTLGKGQTGLVK--LGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLI 73
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H +V++L DV N K+ +YLV+E G L D L G+ P ++A +F Q++ L
Sbjct: 74 EHPHVLKLHDVYEN--KKYLYLVLEHVSGGELFDYLVKK-GRLTP-KEARKFFRQIISAL 129
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
D+ H + H+D+KP NLLL ++I DFG+A + + + T GSP + PE+
Sbjct: 130 DFCHSHSICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEV 186
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G E++ G K D+WS GV L+ + G PF+ DN+ +LLE + R
Sbjct: 187 IRG-EKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQS 245
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAW 354
M D R T+ I++H W
Sbjct: 246 LLRG-MSEVDAARRLTLEHIQKHIW 269
>AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threonine
protein kinase variant C protein.
Length = 736
Score = 127 bits (307), Expect = 8e-29
Identities = 84/265 (31%), Positives = 130/265 (49%), Gaps = 12/265 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + LG+G G VK L + + V + V+REI +L+++
Sbjct: 16 VGPYRLEKTLGKGQTGLVK--LGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLI 73
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H +V++L DV N K+ +YLV+E G L D L G+ P ++A +F Q++ L
Sbjct: 74 EHPHVLKLHDVYEN--KKYLYLVLEHVSGGELFDYLVKK-GRLTP-KEARKFFRQIISAL 129
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
D+ H + H+D+KP NLLL ++I DFG+A + + + T GSP + PE+
Sbjct: 130 DFCHSHSICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEV 186
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G E++ G K D+WS GV L+ + G PF+ DN+ +LLE + R
Sbjct: 187 IRG-EKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQS 245
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAW 354
M D R T+ I++H W
Sbjct: 246 LLRG-MSEVDAARRLTLEHIQKHIW 269
>AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B2 protein.
Length = 674
Score = 127 bits (307), Expect = 8e-29
Identities = 84/265 (31%), Positives = 130/265 (49%), Gaps = 12/265 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + LG+G G VK L + + V + V+REI +L+++
Sbjct: 16 VGPYRLEKTLGKGQTGLVK--LGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLI 73
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H +V++L DV N K+ +YLV+E G L D L G+ P ++A +F Q++ L
Sbjct: 74 EHPHVLKLHDVYEN--KKYLYLVLEHVSGGELFDYLVKK-GRLTP-KEARKFFRQIISAL 129
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
D+ H + H+D+KP NLLL ++I DFG+A + + + T GSP + PE+
Sbjct: 130 DFCHSHSICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEV 186
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G E++ G K D+WS GV L+ + G PF+ DN+ +LLE + R
Sbjct: 187 IRG-EKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQS 245
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAW 354
M D R T+ I++H W
Sbjct: 246 LLRG-MSEVDAARRLTLEHIQKHIW 269
>AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B1 protein.
Length = 674
Score = 127 bits (307), Expect = 8e-29
Identities = 84/265 (31%), Positives = 130/265 (49%), Gaps = 12/265 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + LG+G G VK L + + V + V+REI +L+++
Sbjct: 16 VGPYRLEKTLGKGQTGLVK--LGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLI 73
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H +V++L DV N K+ +YLV+E G L D L G+ P ++A +F Q++ L
Sbjct: 74 EHPHVLKLHDVYEN--KKYLYLVLEHVSGGELFDYLVKK-GRLTP-KEARKFFRQIISAL 129
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
D+ H + H+D+KP NLLL ++I DFG+A + + + T GSP + PE+
Sbjct: 130 DFCHSHSICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEV 186
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G E++ G K D+WS GV L+ + G PF+ DN+ +LLE + R
Sbjct: 187 IRG-EKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQS 245
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAW 354
M D R T+ I++H W
Sbjct: 246 LLRG-MSEVDAARRLTLEHIQKHIW 269
>AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threonine
protein kinase variant A protein.
Length = 668
Score = 127 bits (307), Expect = 8e-29
Identities = 84/265 (31%), Positives = 130/265 (49%), Gaps = 12/265 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + LG+G G VK L + + V + V+REI +L+++
Sbjct: 16 VGPYRLEKTLGKGQTGLVK--LGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLI 73
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H +V++L DV N K+ +YLV+E G L D L G+ P ++A +F Q++ L
Sbjct: 74 EHPHVLKLHDVYEN--KKYLYLVLEHVSGGELFDYLVKK-GRLTP-KEARKFFRQIISAL 129
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
D+ H + H+D+KP NLLL ++I DFG+A + + + T GSP + PE+
Sbjct: 130 DFCHSHSICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEV 186
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G E++ G K D+WS GV L+ + G PF+ DN+ +LLE + R
Sbjct: 187 IRG-EKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQS 245
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAW 354
M D R T+ I++H W
Sbjct: 246 LLRG-MSEVDAARRLTLEHIQKHIW 269
>AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like
protein protein.
Length = 778
Score = 127 bits (307), Expect = 8e-29
Identities = 82/265 (30%), Positives = 133/265 (50%), Gaps = 12/265 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + LG+G G VK L + + V + V+REI +L+++
Sbjct: 31 VGPYRLEKTLGKGQTGLVK--LGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLI 88
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H +V++L DV N K+ +YLV+E G L D L G+ P ++A +F Q++ L
Sbjct: 89 EHPHVLKLHDVYEN--KKYLYLVLEHVSGGELFDYLVKK-GRLTP-KEARKFFRQIVSAL 144
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
D+ H + H+D+KP NLLL ++I DFG+A + + + T GSP + PE+
Sbjct: 145 DFCHSYSICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEV 201
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G E++ G + D+WS GV L+ + G PF+ DN+ +LLE + R
Sbjct: 202 IKG-EKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQS 260
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAW 354
M+ +P R ++ +I++H W
Sbjct: 261 LLRG-MIEVEPEKRLSLEQIQKHPW 284
>BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 126 bits (304), Expect = 2e-28
Identities = 80/273 (29%), Positives = 133/273 (48%), Gaps = 12/273 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + LG+G++ VK L + + V + + RE+Q++++L
Sbjct: 17 VGFYDIEGTLGKGNFAVVK--LGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKML 74
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H ++I+L V+ + K +YLV E+ G + D L + + + +A F Q+L +
Sbjct: 75 DHPHIIKLYQVM--ETKSMLYLVTEYAKNGEIFDYLANHG--RLNESEARRKFWQILSAV 130
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
DY HG+ +VH+D+K NLLL + +KI DFG + F ++ T GSP + PE+
Sbjct: 131 DYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFG---NFFKSGELLATWCGSPPYAAPEV 187
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +Q+ G ++DIWS GV LY + G PF+G + L + +
Sbjct: 188 FEG-QQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLE-GRFRIPYFMSEDCE 245
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFE 362
ML DP+ R T+ +I+ H W+ P +
Sbjct: 246 HLIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQ 278
>BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 126 bits (304), Expect = 2e-28
Identities = 80/273 (29%), Positives = 133/273 (48%), Gaps = 12/273 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + LG+G++ VK L + + V + + RE+Q++++L
Sbjct: 17 VGFYDIEGTLGKGNFAVVK--LGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKML 74
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H ++I+L V+ + K +YLV E+ G + D L + + + +A F Q+L +
Sbjct: 75 DHPHIIKLYQVM--ETKSMLYLVTEYAKNGEIFDYLANHG--RLNESEARRKFWQILSAV 130
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
DY HG+ +VH+D+K NLLL + +KI DFG + F ++ T GSP + PE+
Sbjct: 131 DYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFG---NFFKSGELLATWCGSPPYAAPEV 187
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +Q+ G ++DIWS GV LY + G PF+G + L + +
Sbjct: 188 FEG-QQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLE-GRFRIPYFMSEDCE 245
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFE 362
ML DP+ R T+ +I+ H W+ P +
Sbjct: 246 HLIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQ 278
>BC026060-1|AAH26060.1| 541|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase 2,
beta protein.
Length = 541
Score = 126 bits (304), Expect = 2e-28
Identities = 91/293 (31%), Positives = 141/293 (48%), Gaps = 30/293 (10%)
Query: 88 CKMVGKYVMGDVLGEGSYGKVK-------------EMLDSQSLCRRAVX--------XXX 126
C + +Y + D +G+GSYG VK ++L + L R+A
Sbjct: 159 CVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRP 218
Query: 127 XXXXXXXPNGE-QNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDML 185
P G + V +EI +L+ L H NV++LV+V+ + + +Y+V E V Q +
Sbjct: 219 APGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFEL---VNQGPV 275
Query: 186 ESSPG-KKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAE 244
P K + QA YF L+ G++YLH Q ++H+DIKP NLL+ D +KI DFGV+
Sbjct: 276 MEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSN 335
Query: 245 ALDMFSQEDICYTGQGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGD 303
+ + + G+PAF PE ++ + FSG +D+W+ GVTLY G+ PF +
Sbjct: 336 --EFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDE 393
Query: 304 NVYRLLEAI-SRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ L I S+ ML+++P R V EI+ H WV
Sbjct: 394 RIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 126 bits (304), Expect = 2e-28
Identities = 81/264 (30%), Positives = 133/264 (50%), Gaps = 13/264 (4%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
+Y + LG+G+YGKVK+ +S R +++REI+++ L H
Sbjct: 52 RYEFLETLGKGTYGKVKKARESSG--RLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNH 109
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
++I + +V N K + +VME+ G L D + S ++ +R+A +F Q++ + Y
Sbjct: 110 PHIIAIHEVFENSSK--IVIVMEYASRGDLYDYI--SERQQLSEREARHFFRQIVSAVHY 165
Query: 212 LHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIAN 271
H VVH+D+K N+LL + +KI DFG++ +++ Q T GSP + PEI N
Sbjct: 166 CHQNRVVHRDLKLENILLDANGNIKIADFGLS---NLYHQGKFLQTFCGSPLYASPEIVN 222
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXX 331
G + ++G +VD WS GV LY + G PF+G + L++ IS
Sbjct: 223 G-KPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDACGLIR 281
Query: 332 XXHMLNRDPTLRPTVHEIRRHAWV 355
M+N PT R T+ ++ H WV
Sbjct: 282 WLLMVN--PTRRATLEDVASHWWV 303
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 126 bits (304), Expect = 2e-28
Identities = 81/264 (30%), Positives = 133/264 (50%), Gaps = 13/264 (4%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
+Y + LG+G+YGKVK+ +S R +++REI+++ L H
Sbjct: 52 RYEFLETLGKGTYGKVKKARESSG--RLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNH 109
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
++I + +V N K + +VME+ G L D + S ++ +R+A +F Q++ + Y
Sbjct: 110 PHIIAIHEVFENSSK--IVIVMEYASRGDLYDYI--SERQQLSEREARHFFRQIVSAVHY 165
Query: 212 LHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIAN 271
H VVH+D+K N+LL + +KI DFG++ +++ Q T GSP + PEI N
Sbjct: 166 CHQNRVVHRDLKLENILLDANGNIKIADFGLS---NLYHQGKFLQTFCGSPLYASPEIVN 222
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXX 331
G + ++G +VD WS GV LY + G PF+G + L++ IS
Sbjct: 223 G-KPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDACGLIR 281
Query: 332 XXHMLNRDPTLRPTVHEIRRHAWV 355
M+N PT R T+ ++ H WV
Sbjct: 282 WLLMVN--PTRRATLEDVASHWWV 303
>AF321402-1|AAK91829.1| 588|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta 1 protein.
Length = 588
Score = 126 bits (304), Expect = 2e-28
Identities = 91/293 (31%), Positives = 141/293 (48%), Gaps = 30/293 (10%)
Query: 88 CKMVGKYVMGDVLGEGSYGKVK-------------EMLDSQSLCRRAVX--------XXX 126
C + +Y + D +G+GSYG VK ++L + L R+A
Sbjct: 159 CVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRP 218
Query: 127 XXXXXXXPNGE-QNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDML 185
P G + V +EI +L+ L H NV++LV+V+ + + +Y+V E V Q +
Sbjct: 219 APGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFEL---VNQGPV 275
Query: 186 ESSPG-KKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAE 244
P K + QA YF L+ G++YLH Q ++H+DIKP NLL+ D +KI DFGV+
Sbjct: 276 MEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSN 335
Query: 245 ALDMFSQEDICYTGQGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGD 303
+ + + G+PAF PE ++ + FSG +D+W+ GVTLY G+ PF +
Sbjct: 336 --EFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDE 393
Query: 304 NVYRLLEAI-SRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ L I S+ ML+++P R V EI+ H WV
Sbjct: 394 RIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF321401-1|AAK91830.1| 533|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta 2 protein.
Length = 533
Score = 126 bits (304), Expect = 2e-28
Identities = 91/293 (31%), Positives = 141/293 (48%), Gaps = 30/293 (10%)
Query: 88 CKMVGKYVMGDVLGEGSYGKVK-------------EMLDSQSLCRRAVX--------XXX 126
C + +Y + D +G+GSYG VK ++L + L R+A
Sbjct: 159 CVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRP 218
Query: 127 XXXXXXXPNGE-QNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDML 185
P G + V +EI +L+ L H NV++LV+V+ + + +Y+V E V Q +
Sbjct: 219 APGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFEL---VNQGPV 275
Query: 186 ESSPG-KKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAE 244
P K + QA YF L+ G++YLH Q ++H+DIKP NLL+ D +KI DFGV+
Sbjct: 276 MEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSN 335
Query: 245 ALDMFSQEDICYTGQGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGD 303
+ + + G+PAF PE ++ + FSG +D+W+ GVTLY G+ PF +
Sbjct: 336 --EFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDE 393
Query: 304 NVYRLLEAI-SRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ L I S+ ML+++P R V EI+ H WV
Sbjct: 394 RIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF321387-1|AAL37217.1| 541|Homo sapiens CaMKK beta 1 isoform
protein.
Length = 541
Score = 126 bits (304), Expect = 2e-28
Identities = 91/293 (31%), Positives = 141/293 (48%), Gaps = 30/293 (10%)
Query: 88 CKMVGKYVMGDVLGEGSYGKVK-------------EMLDSQSLCRRAVX--------XXX 126
C + +Y + D +G+GSYG VK ++L + L R+A
Sbjct: 159 CVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRP 218
Query: 127 XXXXXXXPNGE-QNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDML 185
P G + V +EI +L+ L H NV++LV+V+ + + +Y+V E V Q +
Sbjct: 219 APGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFEL---VNQGPV 275
Query: 186 ESSPG-KKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAE 244
P K + QA YF L+ G++YLH Q ++H+DIKP NLL+ D +KI DFGV+
Sbjct: 276 MEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSN 335
Query: 245 ALDMFSQEDICYTGQGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGD 303
+ + + G+PAF PE ++ + FSG +D+W+ GVTLY G+ PF +
Sbjct: 336 --EFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDE 393
Query: 304 NVYRLLEAI-SRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ L I S+ ML+++P R V EI+ H WV
Sbjct: 394 RIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF287631-1|AAK64601.1| 533|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase b2
protein.
Length = 533
Score = 126 bits (304), Expect = 2e-28
Identities = 91/293 (31%), Positives = 141/293 (48%), Gaps = 30/293 (10%)
Query: 88 CKMVGKYVMGDVLGEGSYGKVK-------------EMLDSQSLCRRAVX--------XXX 126
C + +Y + D +G+GSYG VK ++L + L R+A
Sbjct: 159 CVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRP 218
Query: 127 XXXXXXXPNGE-QNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDML 185
P G + V +EI +L+ L H NV++LV+V+ + + +Y+V E V Q +
Sbjct: 219 APGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFEL---VNQGPV 275
Query: 186 ESSPG-KKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAE 244
P K + QA YF L+ G++YLH Q ++H+DIKP NLL+ D +KI DFGV+
Sbjct: 276 MEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSN 335
Query: 245 ALDMFSQEDICYTGQGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGD 303
+ + + G+PAF PE ++ + FSG +D+W+ GVTLY G+ PF +
Sbjct: 336 --EFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDE 393
Query: 304 NVYRLLEAI-SRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ L I S+ ML+++P R V EI+ H WV
Sbjct: 394 RIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF287630-1|AAK64600.1| 588|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase b1
protein.
Length = 588
Score = 126 bits (304), Expect = 2e-28
Identities = 91/293 (31%), Positives = 141/293 (48%), Gaps = 30/293 (10%)
Query: 88 CKMVGKYVMGDVLGEGSYGKVK-------------EMLDSQSLCRRAVX--------XXX 126
C + +Y + D +G+GSYG VK ++L + L R+A
Sbjct: 159 CVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRP 218
Query: 127 XXXXXXXPNGE-QNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDML 185
P G + V +EI +L+ L H NV++LV+V+ + + +Y+V E V Q +
Sbjct: 219 APGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFEL---VNQGPV 275
Query: 186 ESSPG-KKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAE 244
P K + QA YF L+ G++YLH Q ++H+DIKP NLL+ D +KI DFGV+
Sbjct: 276 MEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSN 335
Query: 245 ALDMFSQEDICYTGQGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGD 303
+ + + G+PAF PE ++ + FSG +D+W+ GVTLY G+ PF +
Sbjct: 336 --EFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDE 393
Query: 304 NVYRLLEAI-SRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ L I S+ ML+++P R V EI+ H WV
Sbjct: 394 RIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF101264-1|AAD04566.1| 417|Homo sapiens Ca2+/calmodulin-dependent
kinase kinase protein.
Length = 417
Score = 126 bits (304), Expect = 2e-28
Identities = 91/293 (31%), Positives = 141/293 (48%), Gaps = 30/293 (10%)
Query: 88 CKMVGKYVMGDVLGEGSYGKVK-------------EMLDSQSLCRRAVX--------XXX 126
C + +Y + D +G+GSYG VK ++L + L R+A
Sbjct: 43 CVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRP 102
Query: 127 XXXXXXXPNGE-QNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDML 185
P G + V +EI +L+ L H NV++LV+V+ + + +Y+V E V Q +
Sbjct: 103 APGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFEL---VNQGPV 159
Query: 186 ESSPG-KKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAE 244
P K + QA YF L+ G++YLH Q ++H+DIKP NLL+ D +KI DFGV+
Sbjct: 160 MEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSN 219
Query: 245 ALDMFSQEDICYTGQGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGD 303
+ + + G+PAF PE ++ + FSG +D+W+ GVTLY G+ PF +
Sbjct: 220 --EFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDE 277
Query: 304 NVYRLLEAI-SRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ L I S+ ML+++P R V EI+ H WV
Sbjct: 278 RIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 330
>AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein.
Length = 346
Score = 126 bits (304), Expect = 2e-28
Identities = 80/273 (29%), Positives = 133/273 (48%), Gaps = 12/273 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + LG+G++ VK L + + V + + RE+Q++++L
Sbjct: 15 VGFYDIEGTLGKGNFAVVK--LGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKML 72
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H ++I+L V+ + K +YLV E+ G + D L + + + +A F Q+L +
Sbjct: 73 DHPHIIKLYQVM--ETKSMLYLVTEYAKNGEIFDYLANHG--RLNESEARRKFWQILSAV 128
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
DY HG+ +VH+D+K NLLL + +KI DFG + F ++ T GSP + PE+
Sbjct: 129 DYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFG---NFFKSGELLATWCGSPPYAAPEV 185
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +Q+ G ++DIWS GV LY + G PF+G + L + +
Sbjct: 186 FEG-QQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLE-GRFRIPYFMSEDCE 243
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFE 362
ML DP+ R T+ +I+ H W+ P +
Sbjct: 244 HLIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQ 276
>AB081336-1|BAC19840.1| 541|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta-3 protein.
Length = 541
Score = 126 bits (304), Expect = 2e-28
Identities = 91/293 (31%), Positives = 141/293 (48%), Gaps = 30/293 (10%)
Query: 88 CKMVGKYVMGDVLGEGSYGKVK-------------EMLDSQSLCRRAVX--------XXX 126
C + +Y + D +G+GSYG VK ++L + L R+A
Sbjct: 159 CVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRP 218
Query: 127 XXXXXXXPNGE-QNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDML 185
P G + V +EI +L+ L H NV++LV+V+ + + +Y+V E V Q +
Sbjct: 219 APGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFEL---VNQGPV 275
Query: 186 ESSPG-KKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAE 244
P K + QA YF L+ G++YLH Q ++H+DIKP NLL+ D +KI DFGV+
Sbjct: 276 MEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSN 335
Query: 245 ALDMFSQEDICYTGQGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGD 303
+ + + G+PAF PE ++ + FSG +D+W+ GVTLY G+ PF +
Sbjct: 336 --EFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDE 393
Query: 304 NVYRLLEAI-SRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ L I S+ ML+++P R V EI+ H WV
Sbjct: 394 RIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AB018330-1|BAA34507.2| 557|Homo sapiens KIAA0787 protein protein.
Length = 557
Score = 126 bits (304), Expect = 2e-28
Identities = 91/293 (31%), Positives = 141/293 (48%), Gaps = 30/293 (10%)
Query: 88 CKMVGKYVMGDVLGEGSYGKVK-------------EMLDSQSLCRRAVX--------XXX 126
C + +Y + D +G+GSYG VK ++L + L R+A
Sbjct: 160 CVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRP 219
Query: 127 XXXXXXXPNGE-QNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDML 185
P G + V +EI +L+ L H NV++LV+V+ + + +Y+V E V Q +
Sbjct: 220 APGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFEL---VNQGPV 276
Query: 186 ESSPG-KKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAE 244
P K + QA YF L+ G++YLH Q ++H+DIKP NLL+ D +KI DFGV+
Sbjct: 277 MEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSN 336
Query: 245 ALDMFSQEDICYTGQGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGD 303
+ + + G+PAF PE ++ + FSG +D+W+ GVTLY G+ PF +
Sbjct: 337 --EFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDE 394
Query: 304 NVYRLLEAI-SRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ L I S+ ML+++P R V EI+ H WV
Sbjct: 395 RIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 447
>AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein.
Length = 950
Score = 126 bits (304), Expect = 2e-28
Identities = 80/273 (29%), Positives = 133/273 (48%), Gaps = 12/273 (4%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + LG+G++ VK L + + V + + RE+Q++++L
Sbjct: 41 VGFYDIEGTLGKGNFAVVK--LGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKML 98
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H ++I+L V+ + K +YLV E+ G + D L + + + +A F Q+L +
Sbjct: 99 DHPHIIKLYQVM--ETKSMLYLVTEYAKNGEIFDYLANHG--RLNESEARRKFWQILSAV 154
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
DY HG+ +VH+D+K NLLL + +KI DFG + F ++ T GSP + PE+
Sbjct: 155 DYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFG---NFFKSGELLATWCGSPPYAAPEV 211
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G +Q+ G ++DIWS GV LY + G PF+G + L + +
Sbjct: 212 FEG-QQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLE-GRFRIPYFMSEDCE 269
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFE 362
ML DP+ R T+ +I+ H W+ P +
Sbjct: 270 HLIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQ 302
>AF140507-1|AAD31507.1| 588|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta protein.
Length = 588
Score = 126 bits (303), Expect = 2e-28
Identities = 91/293 (31%), Positives = 140/293 (47%), Gaps = 30/293 (10%)
Query: 88 CKMVGKYVMGDVLGEGSYGKVK-------------EMLDSQSLCRRAVX--------XXX 126
C + +Y + D +G+GSYG VK ++L + L R+A
Sbjct: 159 CVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAAFPRRPPPRGTRP 218
Query: 127 XXXXXXXPNGE-QNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDML 185
P G + V +EI +L+ L H NV++LV+V+ + + +Y+V E V Q +
Sbjct: 219 APGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFEL---VNQGPV 275
Query: 186 ESSPG-KKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAE 244
P K + QA YF L+ G++YLH Q ++H+DIKP NLL+ D +KI DFGV+
Sbjct: 276 MEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSN 335
Query: 245 ALDMFSQEDICYTGQGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGD 303
+ + + G+PAF PE ++ + FSG D+W+ GVTLY G+ PF +
Sbjct: 336 --EFKGSDALLSNYVGTPAFMAPESLSETRKIFSGKAKDVWAMGVTLYCFVFGQCPFMDE 393
Query: 304 NVYRLLEAI-SRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ L I S+ ML+++P R V EI+ H WV
Sbjct: 394 RIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2
(Drosophila) protein.
Length = 685
Score = 124 bits (300), Expect = 5e-28
Identities = 78/263 (29%), Positives = 128/263 (48%), Gaps = 15/263 (5%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
+Y G VLG+G + K EM D + + P+ + + +EI+L RIL H
Sbjct: 81 RYCRGKVLGKGGFAKCYEMTDLTNN-KVYAAKIIPHSRVAKPHQREKIDKEIELHRILHH 139
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKK-FPQRQAHDYFLQLLDGLDY 211
K+V++ Y ++K+ +Y+++E+C + M +K + + Y Q++ GL Y
Sbjct: 140 KHVVQFYH--YFEDKENIYILLEYCSR--RSMAHILKARKVLTEPEVRYYLRQIVSGLKY 195
Query: 212 LHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFS--QEDICYTGQGSPAFQPPEI 269
LH Q ++H+D+K GN + LK+ DFG+A L+ + IC G+P + PE+
Sbjct: 196 LHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTIC----GTPNYLSPEV 251
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
N +Q G + DIW+ G +Y M GR PFE N+ I R
Sbjct: 252 LN--KQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCI-REARYTMPSSLLAPAK 308
Query: 330 XXXXHMLNRDPTLRPTVHEIRRH 352
ML+++P RP++ +I RH
Sbjct: 309 HLIASMLSKNPEDRPSLDDIIRH 331
>AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens
cDNA FLJ40844 fis, clone TRACH2014356, highly similar to
SERINE/THREONINE-PROTEIN KINASE SNK (EC 2.7.1.-). ).
Length = 372
Score = 124 bits (300), Expect = 5e-28
Identities = 78/263 (29%), Positives = 128/263 (48%), Gaps = 15/263 (5%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
+Y G VLG+G + K EM D + + P+ + + +EI+L RIL H
Sbjct: 74 RYCRGKVLGKGGFAKCYEMTDLTNN-KVYAAKIIPHSRVAKPHQREKIDKEIELHRILHH 132
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKK-FPQRQAHDYFLQLLDGLDY 211
K+V++ Y ++K+ +Y+++E+C + M +K + + Y Q++ GL Y
Sbjct: 133 KHVVQFYH--YFEDKENIYILLEYCSR--RSMAHILKARKVLTEPEVRYYLRQIVSGLKY 188
Query: 212 LHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFS--QEDICYTGQGSPAFQPPEI 269
LH Q ++H+D+K GN + LK+ DFG+A L+ + IC G+P + PE+
Sbjct: 189 LHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTIC----GTPNYLSPEV 244
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
N +Q G + DIW+ G +Y M GR PFE N+ I R
Sbjct: 245 LN--KQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCI-REARYTMPSSLLAPAK 301
Query: 330 XXXXHMLNRDPTLRPTVHEIRRH 352
ML+++P RP++ +I RH
Sbjct: 302 HLIASMLSKNPEDRPSLDDIIRH 324
>AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 124 bits (300), Expect = 5e-28
Identities = 78/263 (29%), Positives = 128/263 (48%), Gaps = 15/263 (5%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
+Y G VLG+G + K EM D + + P+ + + +EI+L RIL H
Sbjct: 81 RYCRGKVLGKGGFAKCYEMTDLTNN-KVYAAKIIPHSRVAKPHQREKIDKEIELHRILHH 139
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKK-FPQRQAHDYFLQLLDGLDY 211
K+V++ Y ++K+ +Y+++E+C + M +K + + Y Q++ GL Y
Sbjct: 140 KHVVQFYH--YFEDKENIYILLEYCSR--RSMAHILKARKVLTEPEVRYYLRQIVSGLKY 195
Query: 212 LHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFS--QEDICYTGQGSPAFQPPEI 269
LH Q ++H+D+K GN + LK+ DFG+A L+ + IC G+P + PE+
Sbjct: 196 LHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTIC----GTPNYLSPEV 251
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
N +Q G + DIW+ G +Y M GR PFE N+ I R
Sbjct: 252 LN--KQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCI-REARYTMPSSLLAPAK 308
Query: 330 XXXXHMLNRDPTLRPTVHEIRRH 352
ML+++P RP++ +I RH
Sbjct: 309 HLIASMLSKNPEDRPSLDDIIRH 331
>AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 124 bits (300), Expect = 5e-28
Identities = 78/263 (29%), Positives = 128/263 (48%), Gaps = 15/263 (5%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
+Y G VLG+G + K EM D + + P+ + + +EI+L RIL H
Sbjct: 81 RYCRGKVLGKGGFAKCYEMTDLTNN-KVYAAKIIPHSRVAKPHQREKIDKEIELHRILHH 139
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKK-FPQRQAHDYFLQLLDGLDY 211
K+V++ Y ++K+ +Y+++E+C + M +K + + Y Q++ GL Y
Sbjct: 140 KHVVQFYH--YFEDKENIYILLEYCSR--RSMAHILKARKVLTEPEVRYYLRQIVSGLKY 195
Query: 212 LHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFS--QEDICYTGQGSPAFQPPEI 269
LH Q ++H+D+K GN + LK+ DFG+A L+ + IC G+P + PE+
Sbjct: 196 LHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTIC----GTPNYLSPEV 251
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
N +Q G + DIW+ G +Y M GR PFE N+ I R
Sbjct: 252 LN--KQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCI-REARYTMPSSLLAPAK 308
Query: 330 XXXXHMLNRDPTLRPTVHEIRRH 352
ML+++P RP++ +I RH
Sbjct: 309 HLIASMLSKNPEDRPSLDDIIRH 331
>AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens
cDNA FLJ16763 fis, clone BRAMY3018357, weakly similar
to SNF1-related protein kinase KIN10 (EC 2.7.1.-). ).
Length = 766
Score = 124 bits (298), Expect = 9e-28
Identities = 73/216 (33%), Positives = 115/216 (53%), Gaps = 10/216 (4%)
Query: 140 VQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQA 198
V+REI +L+++ H +V++L DV N K+ +YLV+E G L D L G+ P ++A
Sbjct: 109 VEREIAILKLIEHPHVLKLHDVYEN--KKYLYLVLEHVSGGELFDYLVKK-GRLTP-KEA 164
Query: 199 HDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTG 258
+F Q++ LD+ H + H+D+KP NLLL ++I DFG+A + + + T
Sbjct: 165 RKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETS 221
Query: 259 QGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXX 318
GSP + PE+ G E++ G K D+WS GV L+ + G PF+ DN+ +LLE + R
Sbjct: 222 CGSPHYACPEVIRG-EKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFH 280
Query: 319 XXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAW 354
M+ D R T+ I++H W
Sbjct: 281 MPHFIPPDCQSLLRG-MIEVDAARRLTLEHIQKHIW 315
>BC043487-1|AAH43487.1| 505|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase 1,
alpha protein.
Length = 505
Score = 123 bits (297), Expect = 1e-27
Identities = 74/220 (33%), Positives = 116/220 (52%), Gaps = 6/220 (2%)
Query: 138 QNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQ 197
+ V +EI +L+ L H NV++L++V+ + + +YLV + ++E K F + Q
Sbjct: 194 ERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRK--GPVMEVPCDKPFSEEQ 251
Query: 198 AHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYT 257
A Y ++ GL+YLH Q +VH+DIKP NLLL D +KI DFGV+ + + +
Sbjct: 252 ARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFE--GNDAQLSS 309
Query: 258 GQGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI-SRX 315
G+PAF PE I++ + FSG +D+W++GVTLY G+ PF D + L I +
Sbjct: 310 TAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEP 369
Query: 316 XXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
ML+++P R V +I+ H WV
Sbjct: 370 VVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWV 409
>AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein
protein.
Length = 505
Score = 123 bits (297), Expect = 1e-27
Identities = 74/220 (33%), Positives = 116/220 (52%), Gaps = 6/220 (2%)
Query: 138 QNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQ 197
+ V +EI +L+ L H NV++L++V+ + + +YLV + ++E K F + Q
Sbjct: 194 ERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRK--GPVMEVPCDKPFSEEQ 251
Query: 198 AHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYT 257
A Y ++ GL+YLH Q +VH+DIKP NLLL D +KI DFGV+ + + +
Sbjct: 252 ARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFE--GNDAQLSS 309
Query: 258 GQGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI-SRX 315
G+PAF PE I++ + FSG +D+W++GVTLY G+ PF D + L I +
Sbjct: 310 TAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEP 369
Query: 316 XXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
ML+++P R V +I+ H WV
Sbjct: 370 VVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWV 409
>AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein
protein.
Length = 505
Score = 123 bits (297), Expect = 1e-27
Identities = 74/220 (33%), Positives = 116/220 (52%), Gaps = 6/220 (2%)
Query: 138 QNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQ 197
+ V +EI +L+ L H NV++L++V+ + + +YLV + ++E K F + Q
Sbjct: 194 ERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRK--GPVMEVPCDKPFSEEQ 251
Query: 198 AHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYT 257
A Y ++ GL+YLH Q +VH+DIKP NLLL D +KI DFGV+ + + +
Sbjct: 252 ARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFE--GNDAQLSS 309
Query: 258 GQGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI-SRX 315
G+PAF PE I++ + FSG +D+W++GVTLY G+ PF D + L I +
Sbjct: 310 TAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEP 369
Query: 316 XXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
ML+++P R V +I+ H WV
Sbjct: 370 VVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWV 409
>AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein.
Length = 786
Score = 122 bits (294), Expect = 3e-27
Identities = 82/279 (29%), Positives = 135/279 (48%), Gaps = 15/279 (5%)
Query: 85 KKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREI 144
++K VG Y + LG+G++ VK L + + V + + + RE+
Sbjct: 18 QQKPLRVGFYDIERTLGKGNFAVVK--LARHRVTKTQVAIKIIDKTRLDSSNLEKIYREV 75
Query: 145 QLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFL 203
QL+++L H ++I+L V+ + K +Y+V EF G + D L S+ + +A F
Sbjct: 76 QLMKLLNHPHIIKLYQVM--ETKDMLYIVTEFAKNGEMFDYLTSNG--HLSENEARKKFW 131
Query: 204 QLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKIT---DFGVAEALDMFSQEDICYTGQG 260
Q+L ++Y H +VH+D+K NLLL + +K+ DFG + + + T G
Sbjct: 132 QILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLAGTEDFGFG---NFYKSGEPLSTWCG 188
Query: 261 SPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXX 320
SP + PE+ G E + G ++DIWS GV LY + G PF+G N+ L + +
Sbjct: 189 SPPYAAPEVFEGKE-YEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLE-GRFRI 246
Query: 321 XXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQATP 359
ML DP R T+ +IR+H W++A P
Sbjct: 247 PFFMSQDCESLIRRMLVVDPARRITIAQIRQHRWMRAEP 285
>AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein.
Length = 715
Score = 121 bits (292), Expect = 5e-27
Identities = 71/216 (32%), Positives = 117/216 (54%), Gaps = 10/216 (4%)
Query: 140 VQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQA 198
V+REI +L+++ H +V++L DV N K+ +YLV+E G L D L G+ P ++A
Sbjct: 15 VEREIAILKLIEHPHVLKLHDVYEN--KKYLYLVLEHVSGGELFDYLVKK-GRLTP-KEA 70
Query: 199 HDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTG 258
+F Q++ LD+ H + H+D+KP NLLL ++I DFG+A + + + T
Sbjct: 71 RKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETS 127
Query: 259 QGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXX 318
GSP + PE+ G E++ G + D+WS GV L+ + G PF+ DN+ +LLE + R
Sbjct: 128 CGSPHYACPEVIKG-EKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFH 186
Query: 319 XXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAW 354
M+ +P R ++ +I++H W
Sbjct: 187 MPHFIPPDCQSLLRG-MIEVEPEKRLSLEQIQKHPW 221
>AF321388-1|AAL37218.1| 498|Homo sapiens CaMKK beta 1 isoform
protein.
Length = 498
Score = 118 bits (284), Expect = 5e-26
Identities = 88/288 (30%), Positives = 138/288 (47%), Gaps = 30/288 (10%)
Query: 88 CKMVGKYVMGDVLGEGSYGKVK-------------EMLDSQSLCRRAVX--------XXX 126
C + +Y + D +G+GSYG VK ++L + L R+A
Sbjct: 159 CVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRP 218
Query: 127 XXXXXXXPNGE-QNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDML 185
P G + V +EI +L+ L H NV++LV+V+ + + +Y+V E V Q +
Sbjct: 219 APGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFEL---VNQGPV 275
Query: 186 ESSPG-KKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAE 244
P K + QA YF L+ G++YLH Q ++H+DIKP NLL+ D +KI DFGV+
Sbjct: 276 MEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSN 335
Query: 245 ALDMFSQEDICYTGQGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGD 303
+ + + G+PAF PE ++ + FSG +D+W+ GVTLY G+ PF +
Sbjct: 336 --EFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDE 393
Query: 304 NVYRLLEAI-SRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIR 350
+ L I S+ ML+++P R V EI+
Sbjct: 394 RIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIK 441
>AF321386-1|AAL37216.1| 545|Homo sapiens CaMKK beta 1 isoform
protein.
Length = 545
Score = 118 bits (284), Expect = 5e-26
Identities = 88/288 (30%), Positives = 138/288 (47%), Gaps = 30/288 (10%)
Query: 88 CKMVGKYVMGDVLGEGSYGKVK-------------EMLDSQSLCRRAVX--------XXX 126
C + +Y + D +G+GSYG VK ++L + L R+A
Sbjct: 159 CVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRP 218
Query: 127 XXXXXXXPNGE-QNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDML 185
P G + V +EI +L+ L H NV++LV+V+ + + +Y+V E V Q +
Sbjct: 219 APGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFEL---VNQGPV 275
Query: 186 ESSPG-KKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAE 244
P K + QA YF L+ G++YLH Q ++H+DIKP NLL+ D +KI DFGV+
Sbjct: 276 MEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSN 335
Query: 245 ALDMFSQEDICYTGQGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGD 303
+ + + G+PAF PE ++ + FSG +D+W+ GVTLY G+ PF +
Sbjct: 336 --EFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDE 393
Query: 304 NVYRLLEAI-SRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIR 350
+ L I S+ ML+++P R V EI+
Sbjct: 394 RIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIK 441
>AF321385-1|AAL37215.1| 490|Homo sapiens CaMKK beta 2 isoform
protein.
Length = 490
Score = 118 bits (284), Expect = 5e-26
Identities = 88/288 (30%), Positives = 138/288 (47%), Gaps = 30/288 (10%)
Query: 88 CKMVGKYVMGDVLGEGSYGKVK-------------EMLDSQSLCRRAVX--------XXX 126
C + +Y + D +G+GSYG VK ++L + L R+A
Sbjct: 159 CVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRP 218
Query: 127 XXXXXXXPNGE-QNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDML 185
P G + V +EI +L+ L H NV++LV+V+ + + +Y+V E V Q +
Sbjct: 219 APGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFEL---VNQGPV 275
Query: 186 ESSPG-KKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAE 244
P K + QA YF L+ G++YLH Q ++H+DIKP NLL+ D +KI DFGV+
Sbjct: 276 MEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSN 335
Query: 245 ALDMFSQEDICYTGQGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGD 303
+ + + G+PAF PE ++ + FSG +D+W+ GVTLY G+ PF +
Sbjct: 336 --EFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDE 393
Query: 304 NVYRLLEAI-SRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIR 350
+ L I S+ ML+++P R V EI+
Sbjct: 394 RIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIK 441
>AB081337-1|BAC19841.1| 498|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta-3x protein.
Length = 498
Score = 118 bits (284), Expect = 5e-26
Identities = 88/288 (30%), Positives = 138/288 (47%), Gaps = 30/288 (10%)
Query: 88 CKMVGKYVMGDVLGEGSYGKVK-------------EMLDSQSLCRRAVX--------XXX 126
C + +Y + D +G+GSYG VK ++L + L R+A
Sbjct: 159 CVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRP 218
Query: 127 XXXXXXXPNGE-QNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDML 185
P G + V +EI +L+ L H NV++LV+V+ + + +Y+V E V Q +
Sbjct: 219 APGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFEL---VNQGPV 275
Query: 186 ESSPG-KKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAE 244
P K + QA YF L+ G++YLH Q ++H+DIKP NLL+ D +KI DFGV+
Sbjct: 276 MEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSN 335
Query: 245 ALDMFSQEDICYTGQGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGD 303
+ + + G+PAF PE ++ + FSG +D+W+ GVTLY G+ PF +
Sbjct: 336 --EFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDE 393
Query: 304 NVYRLLEAI-SRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIR 350
+ L I S+ ML+++P R V EI+
Sbjct: 394 RIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIK 441
>AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protein
kinase Kp78 splice variant CTAK75a protein.
Length = 752
Score = 117 bits (282), Expect = 8e-26
Identities = 87/309 (28%), Positives = 140/309 (45%), Gaps = 31/309 (10%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ KVK L L R V P Q + RE+++++IL
Sbjct: 53 IGNYRLLKTIGKGNFAKVK--LARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKIL 110
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG--------VLQDMLESSPGKKFPQR-QAHD- 200
H N+++L +VI + ++ +YL+ME+ G M E KF Q QA
Sbjct: 111 NHPNIVKLFEVI--ETEKTLYLIMEYASGGEVFDYLVAHGKMKEKEARSKFRQGCQAGQT 168
Query: 201 ------------YFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDM 248
F ++ + Y H + +VH+D+K NLLL D +KI DFG + +
Sbjct: 169 IKVQVSFDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTV 228
Query: 249 FSQEDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRL 308
+ D T GSP + PE+ G +++ G +VD+WS GV LY + +G PF+G N+ L
Sbjct: 229 GGKLD---TFCGSPPYAAPELFQG-KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKEL 284
Query: 309 LEAISRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLV 368
E + R L +P R T+ +I + W+ A + + V
Sbjct: 285 RERVLR-GKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFV 343
Query: 369 NPRSRRSDE 377
P SD+
Sbjct: 344 EPELDISDQ 352
>BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein.
Length = 1203
Score = 116 bits (278), Expect = 2e-25
Identities = 77/276 (27%), Positives = 135/276 (48%), Gaps = 15/276 (5%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ VK + + + V + + RE+Q++++L
Sbjct: 5 IGYYEIDRTIGKGNFAVVKRA--THLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKML 62
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H ++I L V+ + ++ +YLV E+ G + D L + + +++A F Q++ +
Sbjct: 63 CHPHIIRLYQVM--ETERMIYLVTEYASGGEIFDHLVAHG--RMAEKEARRKFKQIVTAV 118
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
+ H + +VH+D+K NLLL + +KI DFG + ++F+ + T GSP + PE+
Sbjct: 119 YFCHCRNIVHRDLKAENLLLDANLNIKIADFGFS---NLFTPGQLLKTWCGSPPYAAPEL 175
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G E + G KVDIWS GV LY + G PF+G + L A
Sbjct: 176 FEGKE-YDGPKVDIWSLGVVLYVLVCGALPFDGSTLQN-LRARVLSGKFRIPFFMSTECE 233
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQ---ATPPFE 362
HML DP R ++ +I +H W++ A P F+
Sbjct: 234 HLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFD 269
>BC000318-1|AAH00318.2| 266|Homo sapiens CAMKK2 protein protein.
Length = 266
Score = 116 bits (278), Expect = 2e-25
Identities = 72/214 (33%), Positives = 112/214 (52%), Gaps = 8/214 (3%)
Query: 140 VQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPG-KKFPQRQA 198
V +EI +L+ L H NV++LV+V+ + + +Y+V E V Q + P K + QA
Sbjct: 1 VYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFEL---VNQGPVMEVPTLKPLSEDQA 57
Query: 199 HDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTG 258
YF L+ G++YLH Q ++H+DIKP NLL+ D +KI DFGV+ + + +
Sbjct: 58 RFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSN--EFKGSDALLSNT 115
Query: 259 QGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI-SRXX 316
G+PAF PE ++ + FSG +D+W+ GVTLY G+ PF + + L I S+
Sbjct: 116 VGTPAFMAPESLSETCKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQAL 175
Query: 317 XXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIR 350
ML+++P R V EI+
Sbjct: 176 EFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIK 209
>AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein.
Length = 1371
Score = 116 bits (278), Expect = 2e-25
Identities = 77/276 (27%), Positives = 135/276 (48%), Gaps = 15/276 (5%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ VK + + + V + + RE+Q++++L
Sbjct: 113 IGYYEIDRTIGKGNFAVVKRA--THLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKML 170
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGL 209
H ++I L V+ + ++ +YLV E+ G + D L + + +++A F Q++ +
Sbjct: 171 CHPHIIRLYQVM--ETERMIYLVTEYASGGEIFDHLVAHG--RMAEKEARRKFKQIVTAV 226
Query: 210 DYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
+ H + +VH+D+K NLLL + +KI DFG + ++F+ + T GSP + PE+
Sbjct: 227 YFCHCRNIVHRDLKAENLLLDANLNIKIADFGFS---NLFTPGQLLKTWCGSPPYAAPEL 283
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXX 329
G E + G KVDIWS GV LY + G PF+G + L A
Sbjct: 284 FEGKE-YDGPKVDIWSLGVVLYVLVCGALPFDGSTLQN-LRARVLSGKFRIPFFMSTECE 341
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQ---ATPPFE 362
HML DP R ++ +I +H W++ A P F+
Sbjct: 342 HLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFD 377
>BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 115 bits (277), Expect = 3e-25
Identities = 77/274 (28%), Positives = 126/274 (45%), Gaps = 13/274 (4%)
Query: 85 KKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREI 144
KK+ + + +G LG+G +G V + QS A+ E ++RE+
Sbjct: 124 KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKA-GVEHQLRREV 182
Query: 145 QLLRILRHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLESSPGKKFPQRQAHDYFL 203
++ LRH N++ L Y + ++YL++E+ +G + L+ KF +++ Y
Sbjct: 183 EIQSHLRHPNILRLYG--YFHDATRVYLILEYAPLGTVYRELQKL--SKFDEQRTATYIT 238
Query: 204 QLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA 263
+L + L Y H + V+H+DIKP NLLL LKI DFG + + +C G+
Sbjct: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC----GTLD 294
Query: 264 FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXX 323
+ PPE+ G + KVD+WS GV Y G+ PFE + + ISR
Sbjct: 295 YLPPEMIEG--RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR-VEFTFPDF 351
Query: 324 XXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +P+ RP + E+ H W+ A
Sbjct: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
>BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 115 bits (277), Expect = 3e-25
Identities = 77/274 (28%), Positives = 126/274 (45%), Gaps = 13/274 (4%)
Query: 85 KKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREI 144
KK+ + + +G LG+G +G V + QS A+ E ++RE+
Sbjct: 124 KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKA-GVEHQLRREV 182
Query: 145 QLLRILRHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLESSPGKKFPQRQAHDYFL 203
++ LRH N++ L Y + ++YL++E+ +G + L+ KF +++ Y
Sbjct: 183 EIQSHLRHPNILRLYG--YFHDATRVYLILEYAPLGTVYRELQKL--SKFDEQRTATYIT 238
Query: 204 QLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA 263
+L + L Y H + V+H+DIKP NLLL LKI DFG + + +C G+
Sbjct: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC----GTLD 294
Query: 264 FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXX 323
+ PPE+ G + KVD+WS GV Y G+ PFE + + ISR
Sbjct: 295 YLPPEMIEG--RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR-VEFTFPDF 351
Query: 324 XXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +P+ RP + E+ H W+ A
Sbjct: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
>BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein.
Length = 403
Score = 115 bits (277), Expect = 3e-25
Identities = 77/274 (28%), Positives = 126/274 (45%), Gaps = 13/274 (4%)
Query: 85 KKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREI 144
KK+ + + +G LG+G +G V + QS A+ E ++RE+
Sbjct: 124 KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKA-GVEHQLRREV 182
Query: 145 QLLRILRHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLESSPGKKFPQRQAHDYFL 203
++ LRH N++ L Y + ++YL++E+ +G + L+ KF +++ Y
Sbjct: 183 EIQSHLRHPNILRLYG--YFHDATRVYLILEYAPLGTVYRELQKL--SKFDEQRTATYIT 238
Query: 204 QLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA 263
+L + L Y H + V+H+DIKP NLLL LKI DFG + + +C G+
Sbjct: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC----GTLD 294
Query: 264 FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXX 323
+ PPE+ G + KVD+WS GV Y G+ PFE + + ISR
Sbjct: 295 YLPPEMIEG--RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR-VEFTFPDF 351
Query: 324 XXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +P+ RP + E+ H W+ A
Sbjct: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
>BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 115 bits (277), Expect = 3e-25
Identities = 77/274 (28%), Positives = 126/274 (45%), Gaps = 13/274 (4%)
Query: 85 KKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREI 144
KK+ + + +G LG+G +G V + QS A+ E ++RE+
Sbjct: 124 KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKA-GVEHQLRREV 182
Query: 145 QLLRILRHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLESSPGKKFPQRQAHDYFL 203
++ LRH N++ L Y + ++YL++E+ +G + L+ KF +++ Y
Sbjct: 183 EIQSHLRHPNILRLYG--YFHDATRVYLILEYAPLGTVYRELQKL--SKFDEQRTATYIT 238
Query: 204 QLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA 263
+L + L Y H + V+H+DIKP NLLL LKI DFG + + +C G+
Sbjct: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC----GTLD 294
Query: 264 FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXX 323
+ PPE+ G + KVD+WS GV Y G+ PFE + + ISR
Sbjct: 295 YLPPEMIEG--RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR-VEFTFPDF 351
Query: 324 XXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +P+ RP + E+ H W+ A
Sbjct: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
>AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 115 bits (277), Expect = 3e-25
Identities = 77/274 (28%), Positives = 126/274 (45%), Gaps = 13/274 (4%)
Query: 85 KKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREI 144
KK+ + + +G LG+G +G V + QS A+ E ++RE+
Sbjct: 124 KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKA-GVEHQLRREV 182
Query: 145 QLLRILRHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLESSPGKKFPQRQAHDYFL 203
++ LRH N++ L Y + ++YL++E+ +G + L+ KF +++ Y
Sbjct: 183 EIQSHLRHPNILRLYG--YFHDATRVYLILEYAPLGTVYRELQKL--SKFDEQRTATYIT 238
Query: 204 QLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA 263
+L + L Y H + V+H+DIKP NLLL LKI DFG + + +C G+
Sbjct: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC----GTLD 294
Query: 264 FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXX 323
+ PPE+ G + KVD+WS GV Y G+ PFE + + ISR
Sbjct: 295 YLPPEMIEG--RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR-VEFTFPDF 351
Query: 324 XXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +P+ RP + E+ H W+ A
Sbjct: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
>AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine
kinase protein.
Length = 403
Score = 115 bits (277), Expect = 3e-25
Identities = 77/274 (28%), Positives = 126/274 (45%), Gaps = 13/274 (4%)
Query: 85 KKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREI 144
KK+ + + +G LG+G +G V + QS A+ E ++RE+
Sbjct: 124 KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKA-GVEHQLRREV 182
Query: 145 QLLRILRHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLESSPGKKFPQRQAHDYFL 203
++ LRH N++ L Y + ++YL++E+ +G + L+ KF +++ Y
Sbjct: 183 EIQSHLRHPNILRLYG--YFHDATRVYLILEYAPLGTVYRELQKL--SKFDEQRTATYIT 238
Query: 204 QLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA 263
+L + L Y H + V+H+DIKP NLLL LKI DFG + + +C G+
Sbjct: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC----GTLD 294
Query: 264 FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXX 323
+ PPE+ G + KVD+WS GV Y G+ PFE + + ISR
Sbjct: 295 YLPPEMIEG--RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR-VEFTFPDF 351
Query: 324 XXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +P+ RP + E+ H W+ A
Sbjct: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
>AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase
protein.
Length = 403
Score = 115 bits (277), Expect = 3e-25
Identities = 77/274 (28%), Positives = 126/274 (45%), Gaps = 13/274 (4%)
Query: 85 KKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREI 144
KK+ + + +G LG+G +G V + QS A+ E ++RE+
Sbjct: 124 KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKA-GVEHQLRREV 182
Query: 145 QLLRILRHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLESSPGKKFPQRQAHDYFL 203
++ LRH N++ L Y + ++YL++E+ +G + L+ KF +++ Y
Sbjct: 183 EIQSHLRHPNILRLYG--YFHDATRVYLILEYAPLGTVYRELQKL--SKFDEQRTATYIT 238
Query: 204 QLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA 263
+L + L Y H + V+H+DIKP NLLL LKI DFG + + +C G+
Sbjct: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC----GTLD 294
Query: 264 FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXX 323
+ PPE+ G + KVD+WS GV Y G+ PFE + + ISR
Sbjct: 295 YLPPEMIEG--RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR-VEFTFPDF 351
Query: 324 XXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +P+ RP + E+ H W+ A
Sbjct: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
>AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1
protein.
Length = 403
Score = 115 bits (277), Expect = 3e-25
Identities = 77/274 (28%), Positives = 126/274 (45%), Gaps = 13/274 (4%)
Query: 85 KKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREI 144
KK+ + + +G LG+G +G V + QS A+ E ++RE+
Sbjct: 124 KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKA-GVEHQLRREV 182
Query: 145 QLLRILRHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLESSPGKKFPQRQAHDYFL 203
++ LRH N++ L Y + ++YL++E+ +G + L+ KF +++ Y
Sbjct: 183 EIQSHLRHPNILRLYG--YFHDATRVYLILEYAPLGTVYRELQKL--SKFDEQRTATYIT 238
Query: 204 QLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA 263
+L + L Y H + V+H+DIKP NLLL LKI DFG + + +C G+
Sbjct: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC----GTLD 294
Query: 264 FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXX 323
+ PPE+ G + KVD+WS GV Y G+ PFE + + ISR
Sbjct: 295 YLPPEMIEG--RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR-VEFTFPDF 351
Query: 324 XXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +P+ RP + E+ H W+ A
Sbjct: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
>X66357-1|CAA47001.1| 305|Homo sapiens serine/threonine protein
kinase protein.
Length = 305
Score = 115 bits (276), Expect = 4e-25
Identities = 70/206 (33%), Positives = 108/206 (52%), Gaps = 9/206 (4%)
Query: 100 LGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIELV 159
+GEG+YG V + + ++ + V REI LL+ L+H N++ L+
Sbjct: 10 IGEGTYGVVYKAKNRET--GQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRLL 67
Query: 160 DVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVH 219
DV++N+ +K+YLV EF L+ ++S+PG + P Y QLL G+ + H V+H
Sbjct: 68 DVVHNE--RKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSHRVIH 125
Query: 220 KDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANGAEQFSG 278
+D+KP NLL+ +K+ DFG+A A F YT + ++ PEI G+ +F
Sbjct: 126 RDLKPQNLLINELGAIKLADFGLARA---FGVPLRTYTHEVVTLWYRAPEILLGS-KFYT 181
Query: 279 TKVDIWSSGVTLYNMTTGRYPFEGDN 304
T VDIWS G M T + F GD+
Sbjct: 182 TAVDIWSIGCIFAEMVTRKALFPGDS 207
>AY789470-1|AAV40830.1| 305|Homo sapiens cyclin-dependent kinase 3
protein.
Length = 305
Score = 115 bits (276), Expect = 4e-25
Identities = 70/206 (33%), Positives = 108/206 (52%), Gaps = 9/206 (4%)
Query: 100 LGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIELV 159
+GEG+YG V + + ++ + V REI LL+ L+H N++ L+
Sbjct: 10 IGEGTYGVVYKAKNRET--GQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRLL 67
Query: 160 DVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVH 219
DV++N+ +K+YLV EF L+ ++S+PG + P Y QLL G+ + H V+H
Sbjct: 68 DVVHNE--RKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSHRVIH 125
Query: 220 KDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANGAEQFSG 278
+D+KP NLL+ +K+ DFG+A A F YT + ++ PEI G+ +F
Sbjct: 126 RDLKPQNLLINELGAIKLADFGLARA---FGVPLRTYTHEVVTLWYRAPEILLGS-KFYT 181
Query: 279 TKVDIWSSGVTLYNMTTGRYPFEGDN 304
T VDIWS G M T + F GD+
Sbjct: 182 TAVDIWSIGCIFAEMVTRKALFPGDS 207
>U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase
protein.
Length = 299
Score = 114 bits (275), Expect = 6e-25
Identities = 68/222 (30%), Positives = 113/222 (50%), Gaps = 14/222 (6%)
Query: 134 PNGEQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKK- 192
P+ + + +EI+L RIL HK+V++ Y ++K+ +Y+++E+C + M +K
Sbjct: 12 PHQREKIDKEIELHRILHHKHVVQFYH--YFEDKENIYILLEYCSR--RSMAHILKARKV 67
Query: 193 FPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFS-- 250
+ + Y Q++ GL YLH Q ++H+D+K GN + LK+ DFG+A L+
Sbjct: 68 LTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHR 127
Query: 251 QEDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLE 310
+ IC G+P + PE+ N +Q G + DIW+ G +Y M GR PFE N+
Sbjct: 128 RRTIC----GTPNYLSPEVLN--KQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYR 181
Query: 311 AISRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRH 352
I R ML+++P RP++ +I RH
Sbjct: 182 CI-REARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRH 222
>BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine
kinase 6 protein.
Length = 273
Score = 114 bits (274), Expect = 7e-25
Identities = 78/267 (29%), Positives = 125/267 (46%), Gaps = 12/267 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQN-VQREIQLLRILRH 152
Y +G +GEGSY KVK + + + V P+ + RE+ +LR +RH
Sbjct: 12 YKLGRTIGEGSYSKVK--VATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRH 69
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLES-SPGKKFPQRQAHDYFLQLLDGLDY 211
+++ + + I K+Y+VME D+L++ + P QA D F Q+ + Y
Sbjct: 70 PHIVHVFEFI-EVCNGKLYIVME---AAATDLLQAVQRNGRIPGVQARDLFAQIAGAVRY 125
Query: 212 LHGQGVVHKDIKPGNLLLTLDQ-TLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIA 270
LH +VH+D+K N+LL+ D+ +K+TDFG D+ T GS A+ PE+
Sbjct: 126 LHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGR--QAHGYPDLSTTYCGSAAYASPEVL 183
Query: 271 NGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXX 330
G + K D+WS GV LY M TG PF+ ++ L R
Sbjct: 184 LGI-PYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSERCKA 242
Query: 331 XXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L P+ RP+ ++ R+ W++A
Sbjct: 243 LIAELLQFSPSARPSAGQVARNCWLRA 269
>AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protein
kinase SSTK protein.
Length = 273
Score = 114 bits (274), Expect = 7e-25
Identities = 78/267 (29%), Positives = 125/267 (46%), Gaps = 12/267 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQN-VQREIQLLRILRH 152
Y +G +GEGSY KVK + + + V P+ + RE+ +LR +RH
Sbjct: 12 YKLGRTIGEGSYSKVK--VATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRH 69
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLES-SPGKKFPQRQAHDYFLQLLDGLDY 211
+++ + + I K+Y+VME D+L++ + P QA D F Q+ + Y
Sbjct: 70 PHIVHVFEFI-EVCNGKLYIVME---AAATDLLQAVQRNGRIPGVQARDLFAQIAGAVRY 125
Query: 212 LHGQGVVHKDIKPGNLLLTLDQ-TLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIA 270
LH +VH+D+K N+LL+ D+ +K+TDFG D+ T GS A+ PE+
Sbjct: 126 LHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGR--QAHGYPDLSTTYCGSAAYASPEVL 183
Query: 271 NGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXX 330
G + K D+WS GV LY M TG PF+ ++ L R
Sbjct: 184 LGI-PYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSERCKA 242
Query: 331 XXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L P+ RP+ ++ R+ W++A
Sbjct: 243 LIAELLQFSPSARPSAGQVARNCWLRA 269
>X66364-1|CAA47007.1| 292|Homo sapiens serine/threonine protein
kinase protein.
Length = 292
Score = 113 bits (271), Expect = 2e-24
Identities = 74/224 (33%), Positives = 119/224 (53%), Gaps = 11/224 (4%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
KY + +GEG+YG V + + ++ V + REI LL+ L+H
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRET--HEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
KN++ L DV+++D+K + LV EFC L+ +S G P+ + QLL GL +
Sbjct: 61 KNIVRLHDVLHSDKK--LTLVFEFCDQDLKKYFDSCNGDLDPEI-VKSFLFQLLKGLGFC 117
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIAN 271
H + V+H+D+KP NLL+ + LK+ DFG+A A F CY+ + ++PP++
Sbjct: 118 HSRNVLHRDLKPQNLLINRNGELKLADFGLARA---FGIPVRCYSAEVVTLWYRPPDVLF 174
Query: 272 GAEQFSGTKVDIWSSGVTLYNM-TTGRYPFEGDNVYRLLEAISR 314
GA+ +S T +D+WS+G + GR F G++V L+ I R
Sbjct: 175 GAKLYS-TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFR 217
>BT006680-1|AAP35326.1| 292|Homo sapiens cyclin-dependent kinase 5
protein.
Length = 292
Score = 113 bits (271), Expect = 2e-24
Identities = 74/224 (33%), Positives = 119/224 (53%), Gaps = 11/224 (4%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
KY + +GEG+YG V + + ++ V + REI LL+ L+H
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRET--HEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
KN++ L DV+++D+K + LV EFC L+ +S G P+ + QLL GL +
Sbjct: 61 KNIVRLHDVLHSDKK--LTLVFEFCDQDLKKYFDSCNGDLDPEI-VKSFLFQLLKGLGFC 117
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIAN 271
H + V+H+D+KP NLL+ + LK+ DFG+A A F CY+ + ++PP++
Sbjct: 118 HSRNVLHRDLKPQNLLINRNGELKLADFGLARA---FGIPVRCYSAEVVTLWYRPPDVLF 174
Query: 272 GAEQFSGTKVDIWSSGVTLYNM-TTGRYPFEGDNVYRLLEAISR 314
GA+ +S T +D+WS+G + GR F G++V L+ I R
Sbjct: 175 GAKLYS-TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFR 217
>BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 113 bits (271), Expect = 2e-24
Identities = 79/270 (29%), Positives = 128/270 (47%), Gaps = 13/270 (4%)
Query: 100 LGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIELV 159
LGEG+YG+V+ ++ + AV P +N+++EI + ++L H+NV++
Sbjct: 15 LGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP---ENIKKEICINKMLNHENVVKFY 71
Query: 160 DVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVV 218
+ E YL +E+C G L D +E G P+ A +F QL+ G+ YLHG G+
Sbjct: 72 G--HRREGNIQYLFLEYCSGGELFDRIEPDIG--MPEPDAQRFFHQLMAGVVYLHGIGIT 127
Query: 219 HKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAEQFSG 278
H+DIKP NLLL LKI+DFG+A ++E + G+ + PE+ E F
Sbjct: 128 HRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRRE-FHA 186
Query: 279 TKVDIWSSGVTLYNMTTGRYPFE--GDNVYRLLEAISRXXXXXXXXXXXXXXXXXXXHML 336
VD+WS G+ L M G P++ D+ + + +L
Sbjct: 187 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKIL 246
Query: 337 NRDPTLRPTVHEIRRHAWVQATPPFEPGEK 366
+P+ R T+ +I++ W P + G K
Sbjct: 247 VENPSARITIPDIKKDRWY--NKPLKKGAK 274
>BC005115-1|AAH05115.1| 292|Homo sapiens cyclin-dependent kinase 5
protein.
Length = 292
Score = 113 bits (271), Expect = 2e-24
Identities = 74/224 (33%), Positives = 119/224 (53%), Gaps = 11/224 (4%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
KY + +GEG+YG V + + ++ V + REI LL+ L+H
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRET--HEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
KN++ L DV+++D+K + LV EFC L+ +S G P+ + QLL GL +
Sbjct: 61 KNIVRLHDVLHSDKK--LTLVFEFCDQDLKKYFDSCNGDLDPEI-VKSFLFQLLKGLGFC 117
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIAN 271
H + V+H+D+KP NLL+ + LK+ DFG+A A F CY+ + ++PP++
Sbjct: 118 HSRNVLHRDLKPQNLLINRNGELKLADFGLARA---FGIPVRCYSAEVVTLWYRPPDVLF 174
Query: 272 GAEQFSGTKVDIWSSGVTLYNM-TTGRYPFEGDNVYRLLEAISR 314
GA+ +S T +D+WS+G + GR F G++V L+ I R
Sbjct: 175 GAKLYS-TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFR 217
>BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein.
Length = 476
Score = 113 bits (271), Expect = 2e-24
Identities = 79/270 (29%), Positives = 128/270 (47%), Gaps = 13/270 (4%)
Query: 100 LGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIELV 159
LGEG+YG+V+ ++ + AV P +N+++EI + ++L H+NV++
Sbjct: 15 LGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP---ENIKKEICINKMLNHENVVKFY 71
Query: 160 DVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVV 218
+ E YL +E+C G L D +E G P+ A +F QL+ G+ YLHG G+
Sbjct: 72 G--HRREGNIQYLFLEYCSGGELFDRIEPDIG--MPEPDAQRFFHQLMAGVVYLHGIGIT 127
Query: 219 HKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAEQFSG 278
H+DIKP NLLL LKI+DFG+A ++E + G+ + PE+ E F
Sbjct: 128 HRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRRE-FHA 186
Query: 279 TKVDIWSSGVTLYNMTTGRYPFE--GDNVYRLLEAISRXXXXXXXXXXXXXXXXXXXHML 336
VD+WS G+ L M G P++ D+ + + +L
Sbjct: 187 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKIL 246
Query: 337 NRDPTLRPTVHEIRRHAWVQATPPFEPGEK 366
+P+ R T+ +I++ W P + G K
Sbjct: 247 VENPSARITIPDIKKDRWY--NKPLKKGAK 274
>AY049778-1|AAL15435.1| 292|Homo sapiens cyclin-dependent kinase 5
protein.
Length = 292
Score = 113 bits (271), Expect = 2e-24
Identities = 74/224 (33%), Positives = 119/224 (53%), Gaps = 11/224 (4%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
KY + +GEG+YG V + + ++ V + REI LL+ L+H
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRET--HEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
KN++ L DV+++D+K + LV EFC L+ +S G P+ + QLL GL +
Sbjct: 61 KNIVRLHDVLHSDKK--LTLVFEFCDQDLKKYFDSCNGDLDPEI-VKSFLFQLLKGLGFC 117
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIAN 271
H + V+H+D+KP NLL+ + LK+ DFG+A A F CY+ + ++PP++
Sbjct: 118 HSRNVLHRDLKPQNLLINRNGELKLADFGLARA---FGIPVRCYSAEVVTLWYRPPDVLF 174
Query: 272 GAEQFSGTKVDIWSSGVTLYNM-TTGRYPFEGDNVYRLLEAISR 314
GA+ +S T +D+WS+G + GR F G++V L+ I R
Sbjct: 175 GAKLYS-TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFR 217
>AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 113 bits (271), Expect = 2e-24
Identities = 79/270 (29%), Positives = 128/270 (47%), Gaps = 13/270 (4%)
Query: 100 LGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIELV 159
LGEG+YG+V+ ++ + AV P +N+++EI + ++L H+NV++
Sbjct: 15 LGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP---ENIKKEICINKMLNHENVVKFY 71
Query: 160 DVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVV 218
+ E YL +E+C G L D +E G P+ A +F QL+ G+ YLHG G+
Sbjct: 72 G--HRREGNIQYLFLEYCSGGELFDRIEPDIG--MPEPDAQRFFHQLMAGVVYLHGIGIT 127
Query: 219 HKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAEQFSG 278
H+DIKP NLLL LKI+DFG+A ++E + G+ + PE+ E F
Sbjct: 128 HRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRRE-FHA 186
Query: 279 TKVDIWSSGVTLYNMTTGRYPFE--GDNVYRLLEAISRXXXXXXXXXXXXXXXXXXXHML 336
VD+WS G+ L M G P++ D+ + + +L
Sbjct: 187 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKIL 246
Query: 337 NRDPTLRPTVHEIRRHAWVQATPPFEPGEK 366
+P+ R T+ +I++ W P + G K
Sbjct: 247 VENPSARITIPDIKKDRWY--NKPLKKGAK 274
>AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein.
Length = 476
Score = 113 bits (271), Expect = 2e-24
Identities = 79/270 (29%), Positives = 128/270 (47%), Gaps = 13/270 (4%)
Query: 100 LGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIELV 159
LGEG+YG+V+ ++ + AV P +N+++EI + ++L H+NV++
Sbjct: 15 LGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP---ENIKKEICINKMLNHENVVKFY 71
Query: 160 DVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVV 218
+ E YL +E+C G L D +E G P+ A +F QL+ G+ YLHG G+
Sbjct: 72 G--HRREGNIQYLFLEYCSGGELFDRIEPDIG--MPEPDAQRFFHQLMAGVVYLHGIGIT 127
Query: 219 HKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAEQFSG 278
H+DIKP NLLL LKI+DFG+A ++E + G+ + PE+ E F
Sbjct: 128 HRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRRE-FHA 186
Query: 279 TKVDIWSSGVTLYNMTTGRYPFE--GDNVYRLLEAISRXXXXXXXXXXXXXXXXXXXHML 336
VD+WS G+ L M G P++ D+ + + +L
Sbjct: 187 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKIL 246
Query: 337 NRDPTLRPTVHEIRRHAWVQATPPFEPGEK 366
+P+ R T+ +I++ W P + G K
Sbjct: 247 VENPSARITIPDIKKDRWY--NKPLKKGAK 274
>AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein.
Length = 476
Score = 113 bits (271), Expect = 2e-24
Identities = 79/270 (29%), Positives = 128/270 (47%), Gaps = 13/270 (4%)
Query: 100 LGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIELV 159
LGEG+YG+V+ ++ + AV P +N+++EI + ++L H+NV++
Sbjct: 15 LGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP---ENIKKEICINKMLNHENVVKFY 71
Query: 160 DVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVV 218
+ E YL +E+C G L D +E G P+ A +F QL+ G+ YLHG G+
Sbjct: 72 G--HRREGNIQYLFLEYCSGGELFDRIEPDIG--MPEPDAQRFFHQLMAGVVYLHGIGIT 127
Query: 219 HKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAEQFSG 278
H+DIKP NLLL LKI+DFG+A ++E + G+ + PE+ E F
Sbjct: 128 HRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRRE-FHA 186
Query: 279 TKVDIWSSGVTLYNMTTGRYPFE--GDNVYRLLEAISRXXXXXXXXXXXXXXXXXXXHML 336
VD+WS G+ L M G P++ D+ + + +L
Sbjct: 187 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKIL 246
Query: 337 NRDPTLRPTVHEIRRHAWVQATPPFEPGEK 366
+P+ R T+ +I++ W P + G K
Sbjct: 247 VENPSARITIPDIKKDRWY--NKPLKKGAK 274
>AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein.
Length = 1265
Score = 113 bits (271), Expect = 2e-24
Identities = 72/268 (26%), Positives = 131/268 (48%), Gaps = 9/268 (3%)
Query: 89 KMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLR 148
+++ KYV +GEGS+GK ++ S R+ V E++ +RE+ +L
Sbjct: 6 RIMEKYVRLQKIGEGSFGKAI-LVKSTEDGRQYVIKEINISRMSSKEREES-RREVAVLA 63
Query: 149 ILRHKNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLD 207
++H N+++ + +E +Y+VM++C G L + + G F + Q D+F+Q+
Sbjct: 64 NMKHPNIVQYRESF--EENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICL 121
Query: 208 GLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPP 267
L ++H + ++H+DIK N+ LT D T+++ DFG+A L+ S ++ T G+P + P
Sbjct: 122 ALKHVHDRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLN--STVELARTCIGTPYYLSP 179
Query: 268 EIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXX 327
EI K DIW+ G LY + T ++ FE ++ L+ I
Sbjct: 180 EICENKPY--NNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYD 237
Query: 328 XXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ R+P RP+V+ I ++
Sbjct: 238 LRSLVSQLFKRNPRDRPSVNSILEKGFI 265
>AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein.
Length = 476
Score = 113 bits (271), Expect = 2e-24
Identities = 79/270 (29%), Positives = 128/270 (47%), Gaps = 13/270 (4%)
Query: 100 LGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIELV 159
LGEG+YG+V+ ++ + AV P +N+++EI + ++L H+NV++
Sbjct: 15 LGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP---ENIKKEICINKMLNHENVVKFY 71
Query: 160 DVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVV 218
+ E YL +E+C G L D +E G P+ A +F QL+ G+ YLHG G+
Sbjct: 72 G--HRREGNIQYLFLEYCSGGELFDRIEPDIG--MPEPDAQRFFHQLMAGVVYLHGIGIT 127
Query: 219 HKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAEQFSG 278
H+DIKP NLLL LKI+DFG+A ++E + G+ + PE+ E F
Sbjct: 128 HRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRRE-FHA 186
Query: 279 TKVDIWSSGVTLYNMTTGRYPFE--GDNVYRLLEAISRXXXXXXXXXXXXXXXXXXXHML 336
VD+WS G+ L M G P++ D+ + + +L
Sbjct: 187 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKIL 246
Query: 337 NRDPTLRPTVHEIRRHAWVQATPPFEPGEK 366
+P+ R T+ +I++ W P + G K
Sbjct: 247 VENPSARITIPDIKKDRWY--NKPLKKGAK 274
>BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein.
Length = 1189
Score = 112 bits (269), Expect = 3e-24
Identities = 72/264 (27%), Positives = 128/264 (48%), Gaps = 9/264 (3%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
KYV +GEGS+GK ++ S R+ V E++ +RE+ +L ++H
Sbjct: 3 KYVRLQKIGEGSFGKAI-LVKSTEDGRQYVIKEINISRMSSKEREES-RREVAVLANMKH 60
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
N+++ + +E +Y+VM++C G L + + G F + Q D+F+Q+ L +
Sbjct: 61 PNIVQYRESF--EENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKH 118
Query: 212 LHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIAN 271
+H + ++H+DIK N+ LT D T+++ DFG+A L+ S ++ T G+P + PEI
Sbjct: 119 VHDRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLN--STVELARTCIGTPYYLSPEICE 176
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXX 331
K DIW+ G LY + T ++ FE ++ L+ I
Sbjct: 177 NKPY--NNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSL 234
Query: 332 XXHMLNRDPTLRPTVHEIRRHAWV 355
+ R+P RP+V+ I ++
Sbjct: 235 VSQLFKRNPRDRPSVNSILEKGFI 258
>BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for
IMAGE:4063881) protein.
Length = 403
Score = 112 bits (269), Expect = 3e-24
Identities = 72/264 (27%), Positives = 128/264 (48%), Gaps = 9/264 (3%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
KYV +GEGS+GK ++ S R+ V E++ +RE+ +L ++H
Sbjct: 3 KYVRLQKIGEGSFGKAI-LVKSTEDGRQYVIKEINISRMSSKEREES-RREVAVLANMKH 60
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
N+++ + +E +Y+VM++C G L + + G F + Q D+F+Q+ L +
Sbjct: 61 PNIVQYRESF--EENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKH 118
Query: 212 LHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIAN 271
+H + ++H+DIK N+ LT D T+++ DFG+A L+ S ++ T G+P + PEI
Sbjct: 119 VHDRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLN--STVELARTCIGTPYYLSPEICE 176
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXX 331
K DIW+ G LY + T ++ FE ++ L+ I
Sbjct: 177 NKPY--NNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSL 234
Query: 332 XXHMLNRDPTLRPTVHEIRRHAWV 355
+ R+P RP+V+ I ++
Sbjct: 235 VSQLFKRNPRDRPSVNSILEKGFI 258
>D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinase
protein.
Length = 402
Score = 111 bits (268), Expect = 4e-24
Identities = 74/274 (27%), Positives = 127/274 (46%), Gaps = 13/274 (4%)
Query: 85 KKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREI 144
+K+ + + +G LG+G +G V + QS A+ E ++RE+
Sbjct: 123 QKEAVALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKA-GVEHQLRREV 181
Query: 145 QLLRILRHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLESSPGKKFPQRQAHDYFL 203
++ LRH N++ L Y + ++YL++E+ +G + L+ KF +++ + +
Sbjct: 182 EIQSHLRHPNILRLYG--YFHDATRVYLILEYAPLGTVYRELQKL--SKFDEQRTANLYN 237
Query: 204 QLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA 263
++ + L Y H + V+H+DIKP NLLL LKI DFG + + +C G+
Sbjct: 238 RIANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC----GTLD 293
Query: 264 FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXX 323
+ PPE+ G + KVD+WS GV Y G+ PFE + + ISR
Sbjct: 294 YLPPEMIEG--RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR-VEFTFPDF 350
Query: 324 XXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +P+ RP + E+ H W+ A
Sbjct: 351 VTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 384
>AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 603
Score = 111 bits (267), Expect = 5e-24
Identities = 68/207 (32%), Positives = 106/207 (51%), Gaps = 10/207 (4%)
Query: 149 ILRHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLD 207
++ H +V++L DV N K+ +YLV+E G L D L G+ P ++A +F Q++
Sbjct: 1 LIEHPHVLKLHDVYEN--KKYLYLVLEHVSGGELFDYLVKK-GRLTP-KEARKFFRQIIS 56
Query: 208 GLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPP 267
LD+ H + H+D+KP NLLL ++I DFG+A + + + T GSP + P
Sbjct: 57 ALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACP 113
Query: 268 EIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXX 327
E+ G E++ G K D+WS GV L+ + G PF+ DN+ +LLE + R
Sbjct: 114 EVIRG-EKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDC 172
Query: 328 XXXXXXHMLNRDPTLRPTVHEIRRHAW 354
M D R T+ I++H W
Sbjct: 173 QSLLRG-MSEVDAARRLTLEHIQKHIW 198
>AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein.
Length = 970
Score = 111 bits (267), Expect = 5e-24
Identities = 67/219 (30%), Positives = 111/219 (50%), Gaps = 7/219 (3%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
+ +G++LG+GS+ V S A+ Q VQ E+++ L+H
Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHSGLEVAIKMIDKKAMYKA-GMVQRVQNEVKIHCQLKHP 70
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
+++EL + Y ++ +YLV+E C + + K F + +A + Q++ G+ YLH
Sbjct: 71 SILELYN--YFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLH 128
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGA 273
G++H+D+ NLLLT + +KI DFG+A L M ++ YT G+P + PEIA +
Sbjct: 129 SHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKH--YTLCGTPNYISPEIATRS 186
Query: 274 EQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312
G + D+WS G Y + GR PF+ D V L +
Sbjct: 187 AH--GLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKV 223
>BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine
kinase 1B protein.
Length = 367
Score = 111 bits (266), Expect = 7e-24
Identities = 81/267 (30%), Positives = 123/267 (46%), Gaps = 9/267 (3%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y++G LGEGSY KVK S+ L E+ + REI++L +L H
Sbjct: 12 YLLGINLGEGSYAKVKSAY-SERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHC 70
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
++I+ + I+ K+Y+VME V G L +++++ + +A F QL + Y
Sbjct: 71 SIIKTYE-IFETSHGKVYIVMELAVQGDLLELIKTRGA--LHEDEARKKFHQLSLAIKYC 127
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEAL--DMFSQEDICYTGQGSPAFQPPEIA 270
H VVH+D+K NLLL D +K++DF ++ D + + T GSPA+ PE+
Sbjct: 128 HDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVL 187
Query: 271 NGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXX-XXXXXXXXXX 329
G + DIWS GV LY M G P++ N+ ++L
Sbjct: 188 QGI-PYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECK 246
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQ 356
HML D R + EI H W+Q
Sbjct: 247 DLIYHMLQPDVNRRLHIDEILSHCWMQ 273
>AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific
serine/threonine kinase 1 protein.
Length = 367
Score = 111 bits (266), Expect = 7e-24
Identities = 81/267 (30%), Positives = 123/267 (46%), Gaps = 9/267 (3%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y++G LGEGSY KVK S+ L E+ + REI++L +L H
Sbjct: 12 YLLGINLGEGSYAKVKSAY-SERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHC 70
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
++I+ + I+ K+Y+VME V G L +++++ + +A F QL + Y
Sbjct: 71 SIIKTYE-IFETSHGKVYIVMELAVQGDLLELIKTRGA--LHEDEARKKFHQLSLAIKYC 127
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEAL--DMFSQEDICYTGQGSPAFQPPEIA 270
H VVH+D+K NLLL D +K++DF ++ D + + T GSPA+ PE+
Sbjct: 128 HDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVL 187
Query: 271 NGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXX-XXXXXXXXXX 329
G + DIWS GV LY M G P++ N+ ++L
Sbjct: 188 QGI-PYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECK 246
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQ 356
HML D R + EI H W+Q
Sbjct: 247 DLIYHMLQPDVNRRLHIDEILSHCWMQ 273
>AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine
kinase 1 protein.
Length = 367
Score = 111 bits (266), Expect = 7e-24
Identities = 81/267 (30%), Positives = 123/267 (46%), Gaps = 9/267 (3%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y++G LGEGSY KVK S+ L E+ + REI++L +L H
Sbjct: 12 YLLGINLGEGSYAKVKSAY-SERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHC 70
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
++I+ + I+ K+Y+VME V G L +++++ + +A F QL + Y
Sbjct: 71 SIIKTYE-IFETSHGKVYIVMELAVQGDLLELIKTRGA--LHEDEARKKFHQLSLAIKYC 127
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEAL--DMFSQEDICYTGQGSPAFQPPEIA 270
H VVH+D+K NLLL D +K++DF ++ D + + T GSPA+ PE+
Sbjct: 128 HDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVL 187
Query: 271 NGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXX-XXXXXXXXXX 329
G + DIWS GV LY M G P++ N+ ++L
Sbjct: 188 QGI-PYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECK 246
Query: 330 XXXXHMLNRDPTLRPTVHEIRRHAWVQ 356
HML D R + EI H W+Q
Sbjct: 247 DLIYHMLQPDVNRRLHIDEILSHCWMQ 273
>AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein.
Length = 1311
Score = 110 bits (265), Expect = 9e-24
Identities = 66/229 (28%), Positives = 118/229 (51%), Gaps = 10/229 (4%)
Query: 84 RKKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQRE 143
R + ++ KY + +++GEGS+G+V + + + V +N+QRE
Sbjct: 11 RDPETSVMEKYHVLEMIGEGSFGRVYK--GRRKYSAQVVALKFIPKLGRSEKELRNLQRE 68
Query: 144 IQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFL 203
I+++R LRH N++ ++D D++ + +V ++ G L +LE K P+ Q
Sbjct: 69 IEIMRGLRHPNIVHMLDSFETDKE--VVVVTDYAEGELFQILEDDG--KLPEDQVQAIAA 124
Query: 204 QLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA 263
QL+ L YLH ++H+D+KP N+LL +K+ DFG A A M + + + +G+P
Sbjct: 125 QLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARA--MSTNTMVLTSIKGTPL 182
Query: 264 FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312
+ PE+ E+ D+WS G LY + G PF ++++L+ I
Sbjct: 183 YMSPELVE--ERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLI 229
>D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein.
Length = 656
Score = 110 bits (264), Expect = 1e-23
Identities = 76/275 (27%), Positives = 131/275 (47%), Gaps = 11/275 (4%)
Query: 82 RSRKKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQ 141
R+ K +++ Y + + +G G + KVK L L V + + ++
Sbjct: 4 RTMKDYDELLKYYELHETIGTGGFAKVK--LACHILTGEMVAIKIMDKNTLGSDLPR-IK 60
Query: 142 REIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHD 200
EI+ L+ LRH+++ +L V+ + K+++V+E+C G L D + S + + +
Sbjct: 61 TEIEALKNLRHQHICQLYHVL--ETANKIFMVLEYCPGGELFDYIISQD--RLSEEETRV 116
Query: 201 YFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQG 260
F Q++ + Y+H QG H+D+KP NLL LK+ DFG+ A +++ T G
Sbjct: 117 VFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLC-AKPKGNKDYHLQTCCG 175
Query: 261 SPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXX 320
S A+ PE+ G + + G++ D+WS G+ LY + G PF+ DNV L + I R
Sbjct: 176 SLAYAAPELIQG-KSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMR-GKYDV 233
Query: 321 XXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
ML DP R ++ + H W+
Sbjct: 234 PKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWI 268
>CR457041-1|CAG33322.1| 292|Homo sapiens CDK5 protein.
Length = 292
Score = 110 bits (264), Expect = 1e-23
Identities = 73/224 (32%), Positives = 118/224 (52%), Gaps = 11/224 (4%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
KY + +GEG+YG V + + ++ V + REI LL+ L+H
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRET--HEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
KN++ L DV+++D+K + LV EFC L+ +S G P+ + QLL GL +
Sbjct: 61 KNIVRLHDVLHSDKK--LTLVFEFCDQDLKKYFDSCNGDLDPEI-VKSFLFQLLKGLGFC 117
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIAN 271
H + V+H+D+KP N L+ + LK+ DFG+A A F CY+ + ++PP++
Sbjct: 118 HSRNVLHRDLKPQNPLINRNGELKLADFGLARA---FGIPVRCYSAEVVTLWYRPPDVLF 174
Query: 272 GAEQFSGTKVDIWSSGVTLYNM-TTGRYPFEGDNVYRLLEAISR 314
GA+ +S T +D+WS+G + GR F G++V L+ I R
Sbjct: 175 GAKLYS-TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFR 217
>BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H1
protein.
Length = 424
Score = 110 bits (264), Expect = 1e-23
Identities = 79/274 (28%), Positives = 127/274 (46%), Gaps = 18/274 (6%)
Query: 89 KMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLR 148
++ KY + ++G GS+ +V + + A+ G + + E+++LR
Sbjct: 93 RVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYR----EGREVCESELRVLR 148
Query: 149 ILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGK-KFPQRQAHDYFLQLLD 207
+RH N+I+LV+V + ++++Y+VME G ++ + K F +R A +LD
Sbjct: 149 RVRHANIIQLVEVF--ETQERVYMVMELATG--GELFDRIIAKGSFTERDATRVLQMVLD 204
Query: 208 GLDYLHGQGVVHKDIKPGNLLL---TLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAF 264
G+ YLH G+ H+D+KP NLL D + ITDFG+A A + + T G+P +
Sbjct: 205 GVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKK-GDDCLMKTTCGTPEY 263
Query: 265 QPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXX-- 322
PE+ + VD+W+ GV Y + +G PFE DN RL I R
Sbjct: 264 IAPEVL--VRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPW 321
Query: 323 -XXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+L DP R T + RH WV
Sbjct: 322 PSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV 355
>BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4
(Drosophila) protein.
Length = 970
Score = 110 bits (264), Expect = 1e-23
Identities = 66/219 (30%), Positives = 111/219 (50%), Gaps = 7/219 (3%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
+ +G++LG+GS+ V + A+ Q VQ E+++ L+H
Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKA-GMVQRVQNEVKIHCQLKHP 70
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
+++EL + Y ++ +YLV+E C + + K F + +A + Q++ G+ YLH
Sbjct: 71 SILELYN--YFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLH 128
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGA 273
G++H+D+ NLLLT + +KI DFG+A L M ++ YT G+P + PEIA +
Sbjct: 129 SHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKH--YTLCGTPNYISPEIATRS 186
Query: 274 EQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312
G + D+WS G Y + GR PF+ D V L +
Sbjct: 187 AH--GLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKV 223
>AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase
protein.
Length = 424
Score = 110 bits (264), Expect = 1e-23
Identities = 79/274 (28%), Positives = 127/274 (46%), Gaps = 18/274 (6%)
Query: 89 KMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLR 148
++ KY + ++G GS+ +V + + A+ G + + E+++LR
Sbjct: 93 RVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYR----EGREVCESELRVLR 148
Query: 149 ILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGK-KFPQRQAHDYFLQLLD 207
+RH N+I+LV+V + ++++Y+VME G ++ + K F +R A +LD
Sbjct: 149 RVRHANIIQLVEVF--ETQERVYMVMELATG--GELFDRIIAKGSFTERDATRVLQMVLD 204
Query: 208 GLDYLHGQGVVHKDIKPGNLLL---TLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAF 264
G+ YLH G+ H+D+KP NLL D + ITDFG+A A + + T G+P +
Sbjct: 205 GVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKK-GDDCLMKTTCGTPEY 263
Query: 265 QPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXX-- 322
PE+ + VD+W+ GV Y + +G PFE DN RL I R
Sbjct: 264 IAPEVL--VRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPW 321
Query: 323 -XXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+L DP R T + RH WV
Sbjct: 322 PSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV 355
>AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS
protein.
Length = 462
Score = 110 bits (264), Expect = 1e-23
Identities = 84/294 (28%), Positives = 135/294 (45%), Gaps = 38/294 (12%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
VG Y + +G+G++ KVK L L R V P+ Q + RE+++++ L
Sbjct: 56 VGNYRLLRTIGKGNFAKVK--LARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGL 113
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEF--------------CVGVLQDMLESSPGKKFPQR 196
H N+++L +VI + ++ +YLVME+ C L L +P P
Sbjct: 114 NHPNIVKLFEVI--ETEKTLYLVMEYASAGEPPTLSALPLCHLPLPLHLTLTPLGLCPAG 171
Query: 197 QAHDY---------------FLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFG 241
+ DY F Q++ + Y H + +VH+D+K NLLL + +KI DFG
Sbjct: 172 EVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFG 231
Query: 242 VAEALDMFSQEDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFE 301
+ + S+ D T GSP + PE+ G +++ G +VDIWS GV LY + +G PF+
Sbjct: 232 FSNEFTLGSKLD---TFCGSPPYAAPELFQG-KKYDGPEVDIWSLGVILYTLVSGSLPFD 287
Query: 302 GDNVYRLLEAISRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
G N+ L E + R L +P R T+ +I + W+
Sbjct: 288 GHNLKELRERVLR-GKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWI 340
>X61622-1|CAA43807.1| 298|Homo sapiens CDK2 protein.
Length = 298
Score = 109 bits (263), Expect = 2e-23
Identities = 71/206 (34%), Positives = 103/206 (50%), Gaps = 9/206 (4%)
Query: 100 LGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIELV 159
+GEG+YG V + + L V REI LL+ L H N+++L+
Sbjct: 10 IGEGTYGVVYKARNK--LTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLL 67
Query: 160 DVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVH 219
DVI+ + K +YLV EF L+ +++S P Y QLL GL + H V+H
Sbjct: 68 DVIHTENK--LYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLH 125
Query: 220 KDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANGAEQFSG 278
+D+KP NLL+ + +K+ DFG+A A F YT + ++ PEI G++ +S
Sbjct: 126 RDLKPQNLLINTEGAIKLADFGLARA---FGVPVRTYTHEVVTLWYRAPEILLGSKYYS- 181
Query: 279 TKVDIWSSGVTLYNMTTGRYPFEGDN 304
T VDIWS G M T R F GD+
Sbjct: 182 TAVDIWSLGCIFAEMVTRRALFPGDS 207
>X62071-1|CAA43985.1| 298|Homo sapiens cdk2 protein.
Length = 298
Score = 109 bits (262), Expect = 2e-23
Identities = 72/206 (34%), Positives = 103/206 (50%), Gaps = 9/206 (4%)
Query: 100 LGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIELV 159
+GEG+YG V + + L V REI LL+ L H N+++L+
Sbjct: 10 IGEGTYGVVYKARNK--LTGEVVALKKIRXDTETEGVPSTAIREISLLKELNHPNIVKLL 67
Query: 160 DVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVH 219
DVI+ + K +YLV EF L+ +++S P Y QLL GL + H V+H
Sbjct: 68 DVIHTENK--LYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLH 125
Query: 220 KDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANGAEQFSG 278
+D+KP NLL+ + +K+ DFG+A A F YT + ++ PEI G + +S
Sbjct: 126 RDLKPQNLLINTEGAIKLADFGLARA---FGVPVRTYTHEVVTLWYRAPEILLGCKYYS- 181
Query: 279 TKVDIWSSGVTLYNMTTGRYPFEGDN 304
T VDIWS G M T R F GD+
Sbjct: 182 TAVDIWSLGCIFAEMVTRRALFPGDS 207
>M68520-1|AAA35667.1| 298|Homo sapiens cdc2-related protein kinase
protein.
Length = 298
Score = 109 bits (262), Expect = 2e-23
Identities = 71/206 (34%), Positives = 102/206 (49%), Gaps = 9/206 (4%)
Query: 100 LGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIELV 159
+GEG+YG V + + L V REI LL+ L H N+++L+
Sbjct: 10 IGEGTYGVVYKARNK--LTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLL 67
Query: 160 DVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVH 219
DVI+ + K +YLV EF L+ +++S P Y QLL GL + H V+H
Sbjct: 68 DVIHTENK--LYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLH 125
Query: 220 KDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANGAEQFSG 278
+D+KP NLL+ + +K+ DFG+A A F YT + ++ PEI G + +S
Sbjct: 126 RDLKPQNLLINTEGAIKLADFGLARA---FGVPVRTYTHEVVTLWYRAPEILLGCKYYS- 181
Query: 279 TKVDIWSSGVTLYNMTTGRYPFEGDN 304
T VDIWS G M T R F GD+
Sbjct: 182 TAVDIWSLGCIFAEMVTRRALFPGDS 207
>D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein.
Length = 766
Score = 109 bits (262), Expect = 2e-23
Identities = 86/301 (28%), Positives = 136/301 (45%), Gaps = 18/301 (5%)
Query: 89 KMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLR 148
K+ G Y + LG G + VK + + AV G ++ +E++ ++
Sbjct: 12 KIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATG--HLFQEVRCMK 69
Query: 149 ILRHKNVIELVDVIYNDEKQKMYLVMEFCVG--VLQDMLESSPGKKFPQRQAHDYFLQLL 206
+++H N++ L +VI D + K+YL++E G + +++ G + A YF Q++
Sbjct: 70 LVQHPNIVRLYEVI--DTQTKLYLILELGDGGDMFDYIMKHEEGLN--EDLAKKYFAQIV 125
Query: 207 DGLDYLHGQGVVHKDIKPGNLLLTLDQTL-KITDFGVAEALDMFSQEDICYTGQGSPAFQ 265
+ Y H VVH+D+KP N++ Q L K+TDFG + + F T GS A+
Sbjct: 126 HAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFS---NKFQPGKKLTTSCGSLAYS 182
Query: 266 PPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXX 325
PEI G +++ VDIWS GV L+ + G+ PF+ N L I
Sbjct: 183 APEILLG-DEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMI-MDCKYTVPSHVS 240
Query: 326 XXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNP---RSRRSDELHTST 382
ML RDP R ++ EI H W+Q P P K P S+E H S
Sbjct: 241 KECKDLITRMLQRDPKRRASLEEIENHPWLQGVDP-SPATKYNIPLVSYKNLSEEEHNSI 299
Query: 383 V 383
+
Sbjct: 300 I 300
>BT006821-1|AAP35467.1| 298|Homo sapiens cyclin-dependent kinase 2
protein.
Length = 298
Score = 109 bits (262), Expect = 2e-23
Identities = 71/206 (34%), Positives = 102/206 (49%), Gaps = 9/206 (4%)
Query: 100 LGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIELV 159
+GEG+YG V + + L V REI LL+ L H N+++L+
Sbjct: 10 IGEGTYGVVYKARNK--LTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLL 67
Query: 160 DVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVH 219
DVI+ + K +YLV EF L+ +++S P Y QLL GL + H V+H
Sbjct: 68 DVIHTENK--LYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLH 125
Query: 220 KDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANGAEQFSG 278
+D+KP NLL+ + +K+ DFG+A A F YT + ++ PEI G + +S
Sbjct: 126 RDLKPQNLLINTEGAIKLADFGLARA---FGVPVRTYTHEVVTLWYRAPEILLGCKYYS- 181
Query: 279 TKVDIWSSGVTLYNMTTGRYPFEGDN 304
T VDIWS G M T R F GD+
Sbjct: 182 TAVDIWSLGCIFAEMVTRRALFPGDS 207
>BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase
36, fused homolog (Drosophila) protein.
Length = 1315
Score = 109 bits (262), Expect = 2e-23
Identities = 65/220 (29%), Positives = 114/220 (51%), Gaps = 10/220 (4%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
KY + +++GEGS+G+V + + + V +N+QREI+++R LRH
Sbjct: 3 KYHVLEMIGEGSFGRVYK--GRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH 60
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
N++ ++D D++ + +V ++ G L +LE K P+ Q QL+ L YL
Sbjct: 61 PNIVHMLDSFETDKE--VVVVTDYAEGELFQILEDDG--KLPEDQVQAIAAQLVSALYYL 116
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANG 272
H ++H+D+KP N+LL +K+ DFG A A M + + + +G+P + PE+
Sbjct: 117 HSHRILHRDMKPQNILLAKGGGIKLCDFGFARA--MSTNTMVLTSIKGTPLYMSPELVE- 173
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312
E+ D+WS G LY + G PF ++++L+ I
Sbjct: 174 -ERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLI 212
>BC003065-1|AAH03065.1| 298|Homo sapiens cyclin-dependent kinase 2
protein.
Length = 298
Score = 109 bits (262), Expect = 2e-23
Identities = 71/206 (34%), Positives = 102/206 (49%), Gaps = 9/206 (4%)
Query: 100 LGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIELV 159
+GEG+YG V + + L V REI LL+ L H N+++L+
Sbjct: 10 IGEGTYGVVYKARNK--LTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLL 67
Query: 160 DVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVH 219
DVI+ + K +YLV EF L+ +++S P Y QLL GL + H V+H
Sbjct: 68 DVIHTENK--LYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLH 125
Query: 220 KDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANGAEQFSG 278
+D+KP NLL+ + +K+ DFG+A A F YT + ++ PEI G + +S
Sbjct: 126 RDLKPQNLLINTEGAIKLADFGLARA---FGVPVRTYTHEVVTLWYRAPEILLGCKYYS- 181
Query: 279 TKVDIWSSGVTLYNMTTGRYPFEGDN 304
T VDIWS G M T R F GD+
Sbjct: 182 TAVDIWSLGCIFAEMVTRRALFPGDS 207
>AF512553-1|AAM34794.1| 298|Homo sapiens cyclin-dependent kinase 2
protein.
Length = 298
Score = 109 bits (262), Expect = 2e-23
Identities = 71/206 (34%), Positives = 102/206 (49%), Gaps = 9/206 (4%)
Query: 100 LGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIELV 159
+GEG+YG V + + L V REI LL+ L H N+++L+
Sbjct: 10 IGEGTYGVVYKARNK--LTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLL 67
Query: 160 DVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVH 219
DVI+ + K +YLV EF L+ +++S P Y QLL GL + H V+H
Sbjct: 68 DVIHTENK--LYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLH 125
Query: 220 KDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANGAEQFSG 278
+D+KP NLL+ + +K+ DFG+A A F YT + ++ PEI G + +S
Sbjct: 126 RDLKPQNLLINTEGAIKLADFGLARA---FGVPVRTYTHEVVTLWYRAPEILLGCKYYS- 181
Query: 279 TKVDIWSSGVTLYNMTTGRYPFEGDN 304
T VDIWS G M T R F GD+
Sbjct: 182 TAVDIWSLGCIFAEMVTRRALFPGDS 207
>AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine
kinase protein.
Length = 1315
Score = 109 bits (262), Expect = 2e-23
Identities = 65/220 (29%), Positives = 114/220 (51%), Gaps = 10/220 (4%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
KY + +++GEGS+G+V + + + V +N+QREI+++R LRH
Sbjct: 3 KYHVLEMIGEGSFGRVYK--GRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH 60
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
N++ ++D D++ + +V ++ G L +LE K P+ Q QL+ L YL
Sbjct: 61 PNIVHMLDSFETDKE--VVVVTDYAEGELFQILEDDG--KLPEDQVQAIAAQLVSALYYL 116
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANG 272
H ++H+D+KP N+LL +K+ DFG A A M + + + +G+P + PE+
Sbjct: 117 HSHRILHRDMKPQNILLAKGGGIKLCDFGFARA--MSTNTMVLTSIKGTPLYMSPELVE- 173
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312
E+ D+WS G LY + G PF ++++L+ I
Sbjct: 174 -ERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLI 212
>Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein
kinase protein.
Length = 970
Score = 108 bits (260), Expect = 4e-23
Identities = 65/219 (29%), Positives = 111/219 (50%), Gaps = 7/219 (3%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
+ +G++LG+GS+ V + A+ Q V+ E+++ L+H
Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKA-GMVQRVKNEVKIHCQLKHP 70
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
+++EL + Y ++ +YLV+E C + + K F + +A + Q++ G+ YLH
Sbjct: 71 SILELYN--YFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLH 128
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGA 273
G++H+D+ NLLLT + +KI DFG+A L M ++ YT G+P + PEIA +
Sbjct: 129 SHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKH--YTLCGTPNYISPEIATRS 186
Query: 274 EQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312
G + D+WS G Y + GR PF+ D V L +
Sbjct: 187 AH--GLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKV 223
>BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 108 bits (260), Expect = 4e-23
Identities = 76/275 (27%), Positives = 128/275 (46%), Gaps = 21/275 (7%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG--EQNVQREIQLLRILR 151
Y MG+ LG G + V++ + A G + ++RE+ +LR +R
Sbjct: 13 YEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIR 72
Query: 152 HKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLD 210
H N+I L D+ N K + L++E G L D L + + +A + Q+LDG+
Sbjct: 73 HPNIITLHDIFEN--KTDVVLILELVSGGELFDFLAEK--ESLTEDEATQFLKQILDGVH 128
Query: 211 YLHGQGVVHKDIKPGNLLLTLDQT-----LKITDFGVAEALDMFSQEDICYTGQGSPAFQ 265
YLH + + H D+KP N++L LD+ +K+ DFG+A ++ ++ + G+P F
Sbjct: 129 YLHSKRIAHFDLKPENIML-LDKNVPNPRIKLIDFGIAHKIEAGNEFKNIF---GTPEFV 184
Query: 266 PPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLL---EAISRXXXXXXXX 322
PEI N + G + D+WS GV Y + +G PF G+ L A++
Sbjct: 185 APEIVN--YEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFS 242
Query: 323 XXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +DP R T+ + H+W++A
Sbjct: 243 NTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKA 277
>BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 108 bits (260), Expect = 4e-23
Identities = 76/275 (27%), Positives = 128/275 (46%), Gaps = 21/275 (7%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG--EQNVQREIQLLRILR 151
Y MG+ LG G + V++ + A G + ++RE+ +LR +R
Sbjct: 13 YEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIR 72
Query: 152 HKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLD 210
H N+I L D+ N K + L++E G L D L + + +A + Q+LDG+
Sbjct: 73 HPNIITLHDIFEN--KTDVVLILELVSGGELFDFLAEK--ESLTEDEATQFLKQILDGVH 128
Query: 211 YLHGQGVVHKDIKPGNLLLTLDQT-----LKITDFGVAEALDMFSQEDICYTGQGSPAFQ 265
YLH + + H D+KP N++L LD+ +K+ DFG+A ++ ++ + G+P F
Sbjct: 129 YLHSKRIAHFDLKPENIML-LDKNVPNPRIKLIDFGIAHKIEAGNEFKNIF---GTPEFV 184
Query: 266 PPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLL---EAISRXXXXXXXX 322
PEI N + G + D+WS GV Y + +G PF G+ L A++
Sbjct: 185 APEIVN--YEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFS 242
Query: 323 XXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +DP R T+ + H+W++A
Sbjct: 243 NTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKA 277
>BC028587-1|AAH28587.1| 482|Homo sapiens NEK11 protein protein.
Length = 482
Score = 108 bits (260), Expect = 4e-23
Identities = 79/267 (29%), Positives = 120/267 (44%), Gaps = 11/267 (4%)
Query: 87 KCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXX-PNGEQNVQREIQ 145
K + +YV+ LG GS+G V + D ++ + PN E Q
Sbjct: 22 KTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQ 81
Query: 146 LLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLES--SPGKKFPQRQAHDYF 202
LL L H +++ E+ ++ E+C G L D ++ GK FP+ Q ++F
Sbjct: 82 LLSKLDHPAIVKFHASFV--EQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWF 139
Query: 203 LQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSP 262
+QLL G+DY+H + ++H+D+K N+ L + LKI DFGV+ L D+ T G+P
Sbjct: 140 IQLLLGVDYMHERRILHRDLKSKNVFLK-NNLLKIGDFGVSRLL--MGSCDLATTLTGTP 196
Query: 263 AFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXX 322
+ PE Q TK DIWS LY M + F G N ++ I
Sbjct: 197 HYMSPEALK--HQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTPSLPE 254
Query: 323 XXXXXXXXXXXHMLNRDPTLRPTVHEI 349
MLN++P+LRP+ EI
Sbjct: 255 RYPKELNAIMESMLNKNPSLRPSAIEI 281
>BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 108 bits (260), Expect = 4e-23
Identities = 74/263 (28%), Positives = 125/263 (47%), Gaps = 11/263 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y + + +G G + KVK L L V + + ++ EI+ L+ LRH+
Sbjct: 11 YELHETIGTGGFAKVK--LACHILTGEMVAIKIMDKNTLGSDLPR-IKTEIEALKNLRHQ 67
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
++ +L V+ + K+++V+E+C G L D + S + + + F Q++ + Y+
Sbjct: 68 HICQLYHVL--ETANKIFMVLEYCPGGELFDYIISQD--RLSEEETRVVFRQIVSAVAYV 123
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANG 272
H QG H+D+KP NLL LK+ DFG+ A +++ T GS A+ PE+ G
Sbjct: 124 HSQGYAHRDLKPENLLFDEYHKLKLIDFGLC-AKPKGNKDYHLQTCCGSLAYAAPELIQG 182
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXXX 332
+ + G++ D+WS G+ LY + G PF+ DNV L + I R
Sbjct: 183 -KSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMR-GKYDVPKWLSPSSILLL 240
Query: 333 XHMLNRDPTLRPTVHEIRRHAWV 355
ML DP R ++ + H W+
Sbjct: 241 QQMLQVDPKKRISMKNLLNHPWI 263
>AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 108 bits (260), Expect = 4e-23
Identities = 74/263 (28%), Positives = 125/263 (47%), Gaps = 11/263 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y + + +G G + KVK L L V + + ++ EI+ L+ LRH+
Sbjct: 11 YELHETIGTGGFAKVK--LACHILTGEMVAIKIMDKNTLGSDLPR-IKTEIEALKNLRHQ 67
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
++ +L V+ + K+++V+E+C G L D + S + + + F Q++ + Y+
Sbjct: 68 HICQLYHVL--ETANKIFMVLEYCPGGELFDYIISQD--RLSEEETRVVFRQIVSAVAYV 123
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANG 272
H QG H+D+KP NLL LK+ DFG+ A +++ T GS A+ PE+ G
Sbjct: 124 HSQGYAHRDLKPENLLFDEYHKLKLIDFGLC-AKPKGNKDYHLQTCCGSLAYAAPELIQG 182
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXXX 332
+ + G++ D+WS G+ LY + G PF+ DNV L + I R
Sbjct: 183 -KSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMR-GKYDVPKWLSPSSILLL 240
Query: 333 XHMLNRDPTLRPTVHEIRRHAWV 355
ML DP R ++ + H W+
Sbjct: 241 QQMLQVDPKKRISMKNLLNHPWI 263
>AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 108 bits (260), Expect = 4e-23
Identities = 74/263 (28%), Positives = 125/263 (47%), Gaps = 11/263 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y + + +G G + KVK L L V + + ++ EI+ L+ LRH+
Sbjct: 11 YELHETIGTGGFAKVK--LACHILTGEMVAIKIMDKNTLGSDLPR-IKTEIEALKNLRHQ 67
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
++ +L V+ + K+++V+E+C G L D + S + + + F Q++ + Y+
Sbjct: 68 HICQLYHVL--ETANKIFMVLEYCPGGELFDYIISQD--RLSEEETRVVFRQIVSAVAYV 123
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANG 272
H QG H+D+KP NLL LK+ DFG+ A +++ T GS A+ PE+ G
Sbjct: 124 HSQGYAHRDLKPENLLFDEYHKLKLIDFGLC-AKPKGNKDYHLQTCCGSLAYAAPELIQG 182
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXXX 332
+ + G++ D+WS G+ LY + G PF+ DNV L + I R
Sbjct: 183 -KSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMR-GKYDVPKWLSPSSILLL 240
Query: 333 XHMLNRDPTLRPTVHEIRRHAWV 355
ML DP R ++ + H W+
Sbjct: 241 QQMLQVDPKKRISMKNLLNHPWI 263
>AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase variant protein.
Length = 651
Score = 108 bits (260), Expect = 4e-23
Identities = 74/263 (28%), Positives = 125/263 (47%), Gaps = 11/263 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y + + +G G + KVK L L V + + ++ EI+ L+ LRH+
Sbjct: 11 YELHETIGTGGFAKVK--LACHILTGEMVAIKIMDKNTLGSDLPR-IKTEIEALKNLRHQ 67
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
++ +L V+ + K+++V+E+C G L D + S + + + F Q++ + Y+
Sbjct: 68 HICQLYHVL--ETANKIFMVLEYCPGGELFDYIISQD--RLSEEETRVVFRQIVSAVAYV 123
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANG 272
H QG H+D+KP NLL LK+ DFG+ A +++ T GS A+ PE+ G
Sbjct: 124 HSQGYAHRDLKPENLLFDEYHKLKLIDFGLC-AKPKGNKDYHLQTCCGSLAYAAPELIQG 182
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXXX 332
+ + G++ D+WS G+ LY + G PF+ DNV L + I R
Sbjct: 183 -KSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMR-GKYDVPKWLSPSSILLL 240
Query: 333 XHMLNRDPTLRPTVHEIRRHAWV 355
ML DP R ++ + H W+
Sbjct: 241 QQMLQVDPKKRISMKNLLNHPWI 263
>AB071997-1|BAC06351.1| 470|Homo sapiens NIMA-related kinase 11S
protein.
Length = 470
Score = 108 bits (260), Expect = 4e-23
Identities = 79/267 (29%), Positives = 120/267 (44%), Gaps = 11/267 (4%)
Query: 87 KCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXX-PNGEQNVQREIQ 145
K + +YV+ LG GS+G V + D ++ + PN E Q
Sbjct: 22 KTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQ 81
Query: 146 LLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLES--SPGKKFPQRQAHDYF 202
LL L H +++ E+ ++ E+C G L D ++ GK FP+ Q ++F
Sbjct: 82 LLSKLDHPAIVKFHASFV--EQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWF 139
Query: 203 LQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSP 262
+QLL G+DY+H + ++H+D+K N+ L + LKI DFGV+ L D+ T G+P
Sbjct: 140 IQLLLGVDYMHERRILHRDLKSKNVFLK-NNLLKIGDFGVSRLL--MGSCDLATTLTGTP 196
Query: 263 AFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXX 322
+ PE Q TK DIWS LY M + F G N ++ I
Sbjct: 197 HYMSPEALK--HQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTPSLPE 254
Query: 323 XXXXXXXXXXXHMLNRDPTLRPTVHEI 349
MLN++P+LRP+ EI
Sbjct: 255 RYPKELNAIMESMLNKNPSLRPSAIEI 281
>AB071996-1|BAC06350.1| 645|Homo sapiens NIMA-related kinase 11L
protein.
Length = 645
Score = 108 bits (260), Expect = 4e-23
Identities = 79/267 (29%), Positives = 120/267 (44%), Gaps = 11/267 (4%)
Query: 87 KCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXX-PNGEQNVQREIQ 145
K + +YV+ LG GS+G V + D ++ + PN E Q
Sbjct: 22 KTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQ 81
Query: 146 LLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLES--SPGKKFPQRQAHDYF 202
LL L H +++ E+ ++ E+C G L D ++ GK FP+ Q ++F
Sbjct: 82 LLSKLDHPAIVKFHASFV--EQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWF 139
Query: 203 LQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSP 262
+QLL G+DY+H + ++H+D+K N+ L + LKI DFGV+ L D+ T G+P
Sbjct: 140 IQLLLGVDYMHERRILHRDLKSKNVFLK-NNLLKIGDFGVSRLL--MGSCDLATTLTGTP 196
Query: 263 AFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXX 322
+ PE Q TK DIWS LY M + F G N ++ I
Sbjct: 197 HYMSPEALK--HQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTPSLPE 254
Query: 323 XXXXXXXXXXXHMLNRDPTLRPTVHEI 349
MLN++P+LRP+ EI
Sbjct: 255 RYPKELNAIMESMLNKNPSLRPSAIEI 281
>AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein.
Length = 454
Score = 108 bits (260), Expect = 4e-23
Identities = 76/275 (27%), Positives = 128/275 (46%), Gaps = 21/275 (7%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG--EQNVQREIQLLRILR 151
Y MG+ LG G + V++ + A G + ++RE+ +LR +R
Sbjct: 13 YEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIR 72
Query: 152 HKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLD 210
H N+I L D+ N K + L++E G L D L + + +A + Q+LDG+
Sbjct: 73 HPNIITLHDIFEN--KTDVVLILELVSGGELFDFLAEK--ESLTEDEATQFLKQILDGVH 128
Query: 211 YLHGQGVVHKDIKPGNLLLTLDQT-----LKITDFGVAEALDMFSQEDICYTGQGSPAFQ 265
YLH + + H D+KP N++L LD+ +K+ DFG+A ++ ++ + G+P F
Sbjct: 129 YLHSKRIAHFDLKPENIML-LDKNVPNPRIKLIDFGIAHKIEAGNEFKNIF---GTPEFV 184
Query: 266 PPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLL---EAISRXXXXXXXX 322
PEI N + G + D+WS GV Y + +G PF G+ L A++
Sbjct: 185 APEIVN--YEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFS 242
Query: 323 XXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +DP R T+ + H+W++A
Sbjct: 243 NTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKA 277
>AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein.
Length = 454
Score = 108 bits (260), Expect = 4e-23
Identities = 76/275 (27%), Positives = 128/275 (46%), Gaps = 21/275 (7%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG--EQNVQREIQLLRILR 151
Y MG+ LG G + V++ + A G + ++RE+ +LR +R
Sbjct: 13 YEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIR 72
Query: 152 HKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLD 210
H N+I L D+ N K + L++E G L D L + + +A + Q+LDG+
Sbjct: 73 HPNIITLHDIFEN--KTDVVLILELVSGGELFDFLAEK--ESLTEDEATQFLKQILDGVH 128
Query: 211 YLHGQGVVHKDIKPGNLLLTLDQT-----LKITDFGVAEALDMFSQEDICYTGQGSPAFQ 265
YLH + + H D+KP N++L LD+ +K+ DFG+A ++ ++ + G+P F
Sbjct: 129 YLHSKRIAHFDLKPENIML-LDKNVPNPRIKLIDFGIAHKIEAGNEFKNIF---GTPEFV 184
Query: 266 PPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLL---EAISRXXXXXXXX 322
PEI N + G + D+WS GV Y + +G PF G+ L A++
Sbjct: 185 APEIVN--YEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFS 242
Query: 323 XXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +DP R T+ + H+W++A
Sbjct: 243 NTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKA 277
>BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein.
Length = 765
Score = 108 bits (259), Expect = 5e-23
Identities = 86/301 (28%), Positives = 135/301 (44%), Gaps = 18/301 (5%)
Query: 89 KMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLR 148
K+ G Y + LG G + VK + + AV G ++ +E++ ++
Sbjct: 11 KIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATG--HLFQEVRCMK 68
Query: 149 ILRHKNVIELVDVIYNDEKQKMYLVMEFCVG--VLQDMLESSPGKKFPQRQAHDYFLQLL 206
+++H N++ L +VI D + K+YL++E G + +++ G + A YF Q++
Sbjct: 69 LVQHPNIVRLYEVI--DTQTKLYLILELGDGGDMFDYIMKHEEGLN--EDLAKKYFAQIV 124
Query: 207 DGLDYLHGQGVVHKDIKPGNLLLTLDQTL-KITDFGVAEALDMFSQEDICYTGQGSPAFQ 265
+ Y H VVH+D+KP N++ Q L K+TDFG + + F T GS A+
Sbjct: 125 HAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFS---NKFQPGKKLTTSCGSLAYS 181
Query: 266 PPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXX 325
PEI G +++ VDIWS GV L+ + G+ PF+ N L I
Sbjct: 182 APEILLG-DEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMI-MDCKYTVPSHVS 239
Query: 326 XXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNP---RSRRSDELHTST 382
ML RDP R + EI H W+Q P P K P S+E H S
Sbjct: 240 KECKDLITRMLQRDPKRRAYLEEIENHPWLQGVDP-SPATKYNIPLVSYKNLSEEEHNSI 298
Query: 383 V 383
+
Sbjct: 299 I 299
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 107 bits (258), Expect = 7e-23
Identities = 76/274 (27%), Positives = 129/274 (47%), Gaps = 21/274 (7%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG--EQNVQREIQLLRILR 151
Y G+ LG G + VK+ + + + A G ++++RE+ +L+ ++
Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQ 72
Query: 152 HKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLD 210
H NVI L +V N K + L++E G L D L + + +A ++ Q+L+G+
Sbjct: 73 HPNVITLHEVYEN--KTDVILILELVAGGELFDFLAEK--ESLTEEEATEFLKQILNGVY 128
Query: 211 YLHGQGVVHKDIKPGNLLLTLDQT-----LKITDFGVAEALDMFSQEDICYTGQGSPAFQ 265
YLH + H D+KP N++L LD+ +KI DFG+A +D ++ + G+P F
Sbjct: 129 YLHSLQIAHFDLKPENIML-LDRNVPKPRIKIIDFGLAHKIDFGNEFKNIF---GTPEFV 184
Query: 266 PPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLL---EAISRXXXXXXXX 322
PEI N + G + D+WS GV Y + +G PF GD L A++
Sbjct: 185 APEIVN--YEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFS 242
Query: 323 XXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQ 356
+L +DP R T+ + +H W++
Sbjct: 243 NTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK 276
>DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 107 bits (258), Expect = 7e-23
Identities = 76/274 (27%), Positives = 129/274 (47%), Gaps = 21/274 (7%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG--EQNVQREIQLLRILR 151
Y G+ LG G + VK+ + + + A G ++++RE+ +L+ ++
Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQ 72
Query: 152 HKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLD 210
H NVI L +V N K + L++E G L D L + + +A ++ Q+L+G+
Sbjct: 73 HPNVITLHEVYEN--KTDVILILELVAGGELFDFLAEK--ESLTEEEATEFLKQILNGVY 128
Query: 211 YLHGQGVVHKDIKPGNLLLTLDQT-----LKITDFGVAEALDMFSQEDICYTGQGSPAFQ 265
YLH + H D+KP N++L LD+ +KI DFG+A +D ++ + G+P F
Sbjct: 129 YLHSLQIAHFDLKPENIML-LDRNVPKPRIKIIDFGLAHKIDFGNEFKNIF---GTPEFV 184
Query: 266 PPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLL---EAISRXXXXXXXX 322
PEI N + G + D+WS GV Y + +G PF GD L A++
Sbjct: 185 APEIVN--YEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFS 242
Query: 323 XXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQ 356
+L +DP R T+ + +H W++
Sbjct: 243 NTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK 276
>BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protein
kinase 1 protein.
Length = 367
Score = 107 bits (258), Expect = 7e-23
Identities = 76/274 (27%), Positives = 129/274 (47%), Gaps = 21/274 (7%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG--EQNVQREIQLLRILR 151
Y G+ LG G + VK+ + + + A G ++++RE+ +L+ ++
Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQ 72
Query: 152 HKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLD 210
H NVI L +V N K + L++E G L D L + + +A ++ Q+L+G+
Sbjct: 73 HPNVITLHEVYEN--KTDVILILELVAGGELFDFLAEK--ESLTEEEATEFLKQILNGVY 128
Query: 211 YLHGQGVVHKDIKPGNLLLTLDQT-----LKITDFGVAEALDMFSQEDICYTGQGSPAFQ 265
YLH + H D+KP N++L LD+ +KI DFG+A +D ++ + G+P F
Sbjct: 129 YLHSLQIAHFDLKPENIML-LDRNVPKPRIKIIDFGLAHKIDFGNEFKNIF---GTPEFV 184
Query: 266 PPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLL---EAISRXXXXXXXX 322
PEI N + G + D+WS GV Y + +G PF GD L A++
Sbjct: 185 APEIVN--YEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFS 242
Query: 323 XXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQ 356
+L +DP R T+ + +H W++
Sbjct: 243 NTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK 276
>BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 107 bits (258), Expect = 7e-23
Identities = 76/274 (27%), Positives = 129/274 (47%), Gaps = 21/274 (7%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG--EQNVQREIQLLRILR 151
Y G+ LG G + VK+ + + + A G ++++RE+ +L+ ++
Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQ 72
Query: 152 HKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLD 210
H NVI L +V N K + L++E G L D L + + +A ++ Q+L+G+
Sbjct: 73 HPNVITLHEVYEN--KTDVILILELVAGGELFDFLAEK--ESLTEEEATEFLKQILNGVY 128
Query: 211 YLHGQGVVHKDIKPGNLLLTLDQT-----LKITDFGVAEALDMFSQEDICYTGQGSPAFQ 265
YLH + H D+KP N++L LD+ +KI DFG+A +D ++ + G+P F
Sbjct: 129 YLHSLQIAHFDLKPENIML-LDRNVPKPRIKIIDFGLAHKIDFGNEFKNIF---GTPEFV 184
Query: 266 PPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLL---EAISRXXXXXXXX 322
PEI N + G + D+WS GV Y + +G PF GD L A++
Sbjct: 185 APEIVN--YEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFS 242
Query: 323 XXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQ 356
+L +DP R T+ + +H W++
Sbjct: 243 NTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK 276
>AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein
protein.
Length = 716
Score = 107 bits (258), Expect = 7e-23
Identities = 75/220 (34%), Positives = 116/220 (52%), Gaps = 19/220 (8%)
Query: 90 MVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRI 149
++ KY +G V+G+G++ VKE +D + A+ E ++ E+ +LR
Sbjct: 340 LLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGK---EHLIENEVSILRR 396
Query: 150 LRHKNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDG 208
++H N+I LV+ + + +++LVME G L D + SS K+ +R L +
Sbjct: 397 VKHPNIIMLVEEM--ETATELFLVMELVKGGDLFDAITSST--KYTERDGSAMVYNLANA 452
Query: 209 LDYLHGQGVVHKDIKPGNLLLTL----DQTLKITDFGVAEALDMFSQEDICYTGQGSPAF 264
L YLHG +VH+DIKP NLL+ ++LK+ DFG+A + E YT G+P +
Sbjct: 453 LRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVV-----EGPLYTVCGTPTY 507
Query: 265 QPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDN 304
PEI AE G KVDIW++GV Y + G PF +N
Sbjct: 508 VAPEII--AETGYGLKVDIWAAGVITYILLCGFPPFRSEN 545
>AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 107 bits (258), Expect = 7e-23
Identities = 76/274 (27%), Positives = 129/274 (47%), Gaps = 21/274 (7%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG--EQNVQREIQLLRILR 151
Y G+ LG G + VK+ + + + A G ++++RE+ +L+ ++
Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQ 72
Query: 152 HKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLD 210
H NVI L +V N K + L++E G L D L + + +A ++ Q+L+G+
Sbjct: 73 HPNVITLHEVYEN--KTDVILILELVAGGELFDFLAEK--ESLTEEEATEFLKQILNGVY 128
Query: 211 YLHGQGVVHKDIKPGNLLLTLDQT-----LKITDFGVAEALDMFSQEDICYTGQGSPAFQ 265
YLH + H D+KP N++L LD+ +KI DFG+A +D ++ + G+P F
Sbjct: 129 YLHSLQIAHFDLKPENIML-LDRNVPKPRIKIIDFGLAHKIDFGNEFKNIF---GTPEFV 184
Query: 266 PPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLL---EAISRXXXXXXXX 322
PEI N + G + D+WS GV Y + +G PF GD L A++
Sbjct: 185 APEIVN--YEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFS 242
Query: 323 XXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQ 356
+L +DP R T+ + +H W++
Sbjct: 243 NTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK 276
>AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 107 bits (258), Expect = 7e-23
Identities = 76/274 (27%), Positives = 129/274 (47%), Gaps = 21/274 (7%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG--EQNVQREIQLLRILR 151
Y G+ LG G + VK+ + + + A G ++++RE+ +L+ ++
Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQ 72
Query: 152 HKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLD 210
H NVI L +V N K + L++E G L D L + + +A ++ Q+L+G+
Sbjct: 73 HPNVITLHEVYEN--KTDVILILELVAGGELFDFLAEK--ESLTEEEATEFLKQILNGVY 128
Query: 211 YLHGQGVVHKDIKPGNLLLTLDQT-----LKITDFGVAEALDMFSQEDICYTGQGSPAFQ 265
YLH + H D+KP N++L LD+ +KI DFG+A +D ++ + G+P F
Sbjct: 129 YLHSLQIAHFDLKPENIML-LDRNVPKPRIKIIDFGLAHKIDFGNEFKNIF---GTPEFV 184
Query: 266 PPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLL---EAISRXXXXXXXX 322
PEI N + G + D+WS GV Y + +G PF GD L A++
Sbjct: 185 APEIVN--YEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFS 242
Query: 323 XXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQ 356
+L +DP R T+ + +H W++
Sbjct: 243 NTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK 276
>AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 107 bits (258), Expect = 7e-23
Identities = 76/274 (27%), Positives = 129/274 (47%), Gaps = 21/274 (7%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG--EQNVQREIQLLRILR 151
Y G+ LG G + VK+ + + + A G ++++RE+ +L+ ++
Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQ 72
Query: 152 HKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLD 210
H NVI L +V N K + L++E G L D L + + +A ++ Q+L+G+
Sbjct: 73 HPNVITLHEVYEN--KTDVILILELVAGGELFDFLAEK--ESLTEEEATEFLKQILNGVY 128
Query: 211 YLHGQGVVHKDIKPGNLLLTLDQT-----LKITDFGVAEALDMFSQEDICYTGQGSPAFQ 265
YLH + H D+KP N++L LD+ +KI DFG+A +D ++ + G+P F
Sbjct: 129 YLHSLQIAHFDLKPENIML-LDRNVPKPRIKIIDFGLAHKIDFGNEFKNIF---GTPEFV 184
Query: 266 PPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLL---EAISRXXXXXXXX 322
PEI N + G + D+WS GV Y + +G PF GD L A++
Sbjct: 185 APEIVN--YEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFS 242
Query: 323 XXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQ 356
+L +DP R T+ + +H W++
Sbjct: 243 NTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK 276
>AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein.
Length = 443
Score = 107 bits (258), Expect = 7e-23
Identities = 75/220 (34%), Positives = 116/220 (52%), Gaps = 19/220 (8%)
Query: 90 MVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRI 149
++ KY +G V+G+G++ VKE +D + A+ E ++ E+ +LR
Sbjct: 137 LLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGK---EHLIENEVSILRR 193
Query: 150 LRHKNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDG 208
++H N+I LV+ + + +++LVME G L D + SS K+ +R L +
Sbjct: 194 VKHPNIIMLVEEM--ETATELFLVMELVKGGDLFDAITSST--KYTERDGSAMVYNLANA 249
Query: 209 LDYLHGQGVVHKDIKPGNLLLTL----DQTLKITDFGVAEALDMFSQEDICYTGQGSPAF 264
L YLHG +VH+DIKP NLL+ ++LK+ DFG+A + E YT G+P +
Sbjct: 250 LRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVV-----EGPLYTVCGTPTY 304
Query: 265 QPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDN 304
PEI AE G KVDIW++GV Y + G PF +N
Sbjct: 305 VAPEII--AETGYGLKVDIWAAGVITYILLCGFPPFRSEN 342
>AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein
DKFZp761I032 variant protein.
Length = 796
Score = 107 bits (258), Expect = 7e-23
Identities = 75/220 (34%), Positives = 116/220 (52%), Gaps = 19/220 (8%)
Query: 90 MVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRI 149
++ KY +G V+G+G++ VKE +D + A+ E ++ E+ +LR
Sbjct: 420 LLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGK---EHLIENEVSILRR 476
Query: 150 LRHKNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDG 208
++H N+I LV+ + + +++LVME G L D + SS K+ +R L +
Sbjct: 477 VKHPNIIMLVEEM--ETATELFLVMELVKGGDLFDAITSST--KYTERDGSAMVYNLANA 532
Query: 209 LDYLHGQGVVHKDIKPGNLLLTL----DQTLKITDFGVAEALDMFSQEDICYTGQGSPAF 264
L YLHG +VH+DIKP NLL+ ++LK+ DFG+A + E YT G+P +
Sbjct: 533 LRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVV-----EGPLYTVCGTPTY 587
Query: 265 QPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDN 304
PEI AE G KVDIW++GV Y + G PF +N
Sbjct: 588 VAPEII--AETGYGLKVDIWAAGVITYILLCGFPPFRSEN 625
>AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein
DKFZp781I035 variant protein.
Length = 1433
Score = 107 bits (258), Expect = 7e-23
Identities = 76/274 (27%), Positives = 129/274 (47%), Gaps = 21/274 (7%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG--EQNVQREIQLLRILR 151
Y G+ LG G + VK+ + + + A G ++++RE+ +L+ ++
Sbjct: 16 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQ 75
Query: 152 HKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYFLQLLDGLD 210
H NVI L +V N K + L++E G L D L + + +A ++ Q+L+G+
Sbjct: 76 HPNVITLHEVYEN--KTDVILILELVAGGELFDFLAEK--ESLTEEEATEFLKQILNGVY 131
Query: 211 YLHGQGVVHKDIKPGNLLLTLDQT-----LKITDFGVAEALDMFSQEDICYTGQGSPAFQ 265
YLH + H D+KP N++L LD+ +KI DFG+A +D ++ + G+P F
Sbjct: 132 YLHSLQIAHFDLKPENIML-LDRNVPKPRIKIIDFGLAHKIDFGNEFKNIF---GTPEFV 187
Query: 266 PPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLL---EAISRXXXXXXXX 322
PEI N + G + D+WS GV Y + +G PF GD L A++
Sbjct: 188 APEIVN--YEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFS 245
Query: 323 XXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQ 356
+L +DP R T+ + +H W++
Sbjct: 246 NTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK 279
>AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein.
Length = 765
Score = 107 bits (257), Expect = 9e-23
Identities = 87/303 (28%), Positives = 137/303 (45%), Gaps = 22/303 (7%)
Query: 89 KMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLR 148
K+ G Y + LG G + VK + + AV G ++ +E++ ++
Sbjct: 11 KIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATG--HLFQEVRCMK 68
Query: 149 ILRHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDML---ESSPGKKFPQRQAHDYFLQ 204
+++H N++ L +VI D + K+YL++E G + D + E + P++ YF Q
Sbjct: 69 LVQHPNIVRLYEVI--DTQTKLYLILELGDEGDMFDYIMKHEEGLNEDLPKK----YFAQ 122
Query: 205 LLDGLDYLHGQGVVHKDIKPGNLLLTLDQTL-KITDFGVAEALDMFSQEDICYTGQGSPA 263
++ + Y H VVH+D+KP N++ Q L K+TDFG + + F T GS A
Sbjct: 123 IVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFS---NKFQPGKKLTTSCGSLA 179
Query: 264 FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXX 323
+ PEI G +++ VDIWS GV L+ + G+ PF+ N L I
Sbjct: 180 YSAPEILLG-DEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMI-MDCKYTVPSH 237
Query: 324 XXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNP---RSRRSDELHT 380
ML RDP R ++ EI H W+Q P P K P S+E H
Sbjct: 238 VSKECKDLITRMLQRDPKRRASLEEIENHPWLQGVDP-SPATKYNIPLVSYKNLSEEEHN 296
Query: 381 STV 383
S +
Sbjct: 297 SII 299
>AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 106 bits (254), Expect = 2e-22
Identities = 72/215 (33%), Positives = 111/215 (51%), Gaps = 19/215 (8%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
+Y +G +G+G++ VKE ++ + A+ E +Q E+ +LR ++H
Sbjct: 389 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK---EHMIQNEVSILRRVKH 445
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
N++ L++ + D ++YLVME G L D + S+ K+ +R A L + Y
Sbjct: 446 PNIVLLIEEM--DVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKY 501
Query: 212 LHGQGVVHKDIKPGNLLLTLDQ----TLKITDFGVAEALDMFSQEDICYTGQGSPAFQPP 267
LH +VH+DIKP NLL+ Q +LK+ DFG+A +D YT G+P + P
Sbjct: 502 LHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVD-----GPLYTVCGTPTYVAP 556
Query: 268 EIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEG 302
EI AE G KVDIW++GV Y + G PF G
Sbjct: 557 EII--AETGYGLKVDIWAAGVITYILLCGFPPFRG 589
>AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 106 bits (254), Expect = 2e-22
Identities = 72/215 (33%), Positives = 111/215 (51%), Gaps = 19/215 (8%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
+Y +G +G+G++ VKE ++ + A+ E +Q E+ +LR ++H
Sbjct: 389 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK---EHMIQNEVSILRRVKH 445
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
N++ L++ + D ++YLVME G L D + S+ K+ +R A L + Y
Sbjct: 446 PNIVLLIEEM--DVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKY 501
Query: 212 LHGQGVVHKDIKPGNLLLTLDQ----TLKITDFGVAEALDMFSQEDICYTGQGSPAFQPP 267
LH +VH+DIKP NLL+ Q +LK+ DFG+A +D YT G+P + P
Sbjct: 502 LHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVD-----GPLYTVCGTPTYVAP 556
Query: 268 EIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEG 302
EI AE G KVDIW++GV Y + G PF G
Sbjct: 557 EII--AETGYGLKVDIWAAGVITYILLCGFPPFRG 589
>AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 106 bits (254), Expect = 2e-22
Identities = 72/215 (33%), Positives = 111/215 (51%), Gaps = 19/215 (8%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
+Y +G +G+G++ VKE ++ + A+ E +Q E+ +LR ++H
Sbjct: 389 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK---EHMIQNEVSILRRVKH 445
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
N++ L++ + D ++YLVME G L D + S+ K+ +R A L + Y
Sbjct: 446 PNIVLLIEEM--DVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKY 501
Query: 212 LHGQGVVHKDIKPGNLLLTLDQ----TLKITDFGVAEALDMFSQEDICYTGQGSPAFQPP 267
LH +VH+DIKP NLL+ Q +LK+ DFG+A +D YT G+P + P
Sbjct: 502 LHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVD-----GPLYTVCGTPTYVAP 556
Query: 268 EIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEG 302
EI AE G KVDIW++GV Y + G PF G
Sbjct: 557 EII--AETGYGLKVDIWAAGVITYILLCGFPPFRG 589
>AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 106 bits (254), Expect = 2e-22
Identities = 72/215 (33%), Positives = 111/215 (51%), Gaps = 19/215 (8%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
+Y +G +G+G++ VKE ++ + A+ E +Q E+ +LR ++H
Sbjct: 389 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK---EHMIQNEVSILRRVKH 445
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
N++ L++ + D ++YLVME G L D + S+ K+ +R A L + Y
Sbjct: 446 PNIVLLIEEM--DVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKY 501
Query: 212 LHGQGVVHKDIKPGNLLLTLDQ----TLKITDFGVAEALDMFSQEDICYTGQGSPAFQPP 267
LH +VH+DIKP NLL+ Q +LK+ DFG+A +D YT G+P + P
Sbjct: 502 LHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVD-----GPLYTVCGTPTYVAP 556
Query: 268 EIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEG 302
EI AE G KVDIW++GV Y + G PF G
Sbjct: 557 EII--AETGYGLKVDIWAAGVITYILLCGFPPFRG 589
>AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 433
Score = 106 bits (254), Expect = 2e-22
Identities = 72/215 (33%), Positives = 111/215 (51%), Gaps = 19/215 (8%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
+Y +G +G+G++ VKE ++ + A+ E +Q E+ +LR ++H
Sbjct: 82 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK---EHMIQNEVSILRRVKH 138
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
N++ L++ + D ++YLVME G L D + S+ K+ +R A L + Y
Sbjct: 139 PNIVLLIEEM--DVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKY 194
Query: 212 LHGQGVVHKDIKPGNLLLTLDQ----TLKITDFGVAEALDMFSQEDICYTGQGSPAFQPP 267
LH +VH+DIKP NLL+ Q +LK+ DFG+A +D YT G+P + P
Sbjct: 195 LHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVD-----GPLYTVCGTPTYVAP 249
Query: 268 EIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEG 302
EI AE G KVDIW++GV Y + G PF G
Sbjct: 250 EII--AETGYGLKVDIWAAGVITYILLCGFPPFRG 282
>AL157760-2|CAH70168.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 106 bits (254), Expect = 2e-22
Identities = 72/215 (33%), Positives = 111/215 (51%), Gaps = 19/215 (8%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
+Y +G +G+G++ VKE ++ + A+ E +Q E+ +LR ++H
Sbjct: 389 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK---EHMIQNEVSILRRVKH 445
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
N++ L++ + D ++YLVME G L D + S+ K+ +R A L + Y
Sbjct: 446 PNIVLLIEEM--DVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKY 501
Query: 212 LHGQGVVHKDIKPGNLLLTLDQ----TLKITDFGVAEALDMFSQEDICYTGQGSPAFQPP 267
LH +VH+DIKP NLL+ Q +LK+ DFG+A +D YT G+P + P
Sbjct: 502 LHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVD-----GPLYTVCGTPTYVAP 556
Query: 268 EIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEG 302
EI AE G KVDIW++GV Y + G PF G
Sbjct: 557 EII--AETGYGLKVDIWAAGVITYILLCGFPPFRG 589
>AL157760-1|CAH70167.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 106 bits (254), Expect = 2e-22
Identities = 72/215 (33%), Positives = 111/215 (51%), Gaps = 19/215 (8%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
+Y +G +G+G++ VKE ++ + A+ E +Q E+ +LR ++H
Sbjct: 389 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK---EHMIQNEVSILRRVKH 445
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
N++ L++ + D ++YLVME G L D + S+ K+ +R A L + Y
Sbjct: 446 PNIVLLIEEM--DVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKY 501
Query: 212 LHGQGVVHKDIKPGNLLLTLDQ----TLKITDFGVAEALDMFSQEDICYTGQGSPAFQPP 267
LH +VH+DIKP NLL+ Q +LK+ DFG+A +D YT G+P + P
Sbjct: 502 LHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVD-----GPLYTVCGTPTYVAP 556
Query: 268 EIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEG 302
EI AE G KVDIW++GV Y + G PF G
Sbjct: 557 EII--AETGYGLKVDIWAAGVITYILLCGFPPFRG 589
>AL157694-2|CAH70657.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 106 bits (254), Expect = 2e-22
Identities = 72/215 (33%), Positives = 111/215 (51%), Gaps = 19/215 (8%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
+Y +G +G+G++ VKE ++ + A+ E +Q E+ +LR ++H
Sbjct: 389 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK---EHMIQNEVSILRRVKH 445
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
N++ L++ + D ++YLVME G L D + S+ K+ +R A L + Y
Sbjct: 446 PNIVLLIEEM--DVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKY 501
Query: 212 LHGQGVVHKDIKPGNLLLTLDQ----TLKITDFGVAEALDMFSQEDICYTGQGSPAFQPP 267
LH +VH+DIKP NLL+ Q +LK+ DFG+A +D YT G+P + P
Sbjct: 502 LHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVD-----GPLYTVCGTPTYVAP 556
Query: 268 EIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEG 302
EI AE G KVDIW++GV Y + G PF G
Sbjct: 557 EII--AETGYGLKVDIWAAGVITYILLCGFPPFRG 589
>AL157694-1|CAH70656.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 106 bits (254), Expect = 2e-22
Identities = 72/215 (33%), Positives = 111/215 (51%), Gaps = 19/215 (8%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
+Y +G +G+G++ VKE ++ + A+ E +Q E+ +LR ++H
Sbjct: 389 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK---EHMIQNEVSILRRVKH 445
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
N++ L++ + D ++YLVME G L D + S+ K+ +R A L + Y
Sbjct: 446 PNIVLLIEEM--DVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKY 501
Query: 212 LHGQGVVHKDIKPGNLLLTLDQ----TLKITDFGVAEALDMFSQEDICYTGQGSPAFQPP 267
LH +VH+DIKP NLL+ Q +LK+ DFG+A +D YT G+P + P
Sbjct: 502 LHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVD-----GPLYTVCGTPTYVAP 556
Query: 268 EIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEG 302
EI AE G KVDIW++GV Y + G PF G
Sbjct: 557 EII--AETGYGLKVDIWAAGVITYILLCGFPPFRG 589
>AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens
cDNA FLJ16392 fis, clone TRACH2020048, moderately
similar to Mus musculus serine/threonine-protein kinase
NEK3 (Nek3) mRNA. ).
Length = 510
Score = 106 bits (254), Expect = 2e-22
Identities = 69/259 (26%), Positives = 122/259 (47%), Gaps = 10/259 (3%)
Query: 88 CKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLL 147
C + Y++ ++GEGS+G+ +L + N QN ++E LL
Sbjct: 19 CPSMDDYMVLRMIGEGSFGRA--LLVQHESSNQMFAMKEIRLPKSFSN-TQNSRKEAVLL 75
Query: 148 RILRHKNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLL 206
++H N++ + + + +Y+VME+C G L ++ GK FP+ ++F Q+
Sbjct: 76 AKMKHPNIVAFKESF--EAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMC 133
Query: 207 DGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQP 266
G++++H + V+H+DIK N+ LT + +K+ DFG A L + T G+P + P
Sbjct: 134 LGVNHIHKKRVLHRDIKSKNIFLTQNGKVKLGDFGSARLLS--NPMAFACTYVGTPYYVP 191
Query: 267 PEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXX 326
PEI K DIWS G LY + T ++PF+ ++ L+ + +
Sbjct: 192 PEIWENLPY--NNKSDIWSLGCILYELCTLKHPFQANSWKNLILKVCQGCISPLPSHYSY 249
Query: 327 XXXXXXXHMLNRDPTLRPT 345
M R+P+ RP+
Sbjct: 250 ELQFLVKQMFKRNPSHRPS 268
>AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein.
Length = 794
Score = 106 bits (254), Expect = 2e-22
Identities = 72/215 (33%), Positives = 111/215 (51%), Gaps = 19/215 (8%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
+Y +G +G+G++ VKE ++ + A+ E +Q E+ +LR ++H
Sbjct: 454 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK---EHMIQNEVSILRRVKH 510
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
N++ L++ + D ++YLVME G L D + S+ K+ +R A L + Y
Sbjct: 511 PNIVLLIEEM--DVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKY 566
Query: 212 LHGQGVVHKDIKPGNLLLTLDQ----TLKITDFGVAEALDMFSQEDICYTGQGSPAFQPP 267
LH +VH+DIKP NLL+ Q +LK+ DFG+A +D YT G+P + P
Sbjct: 567 LHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVD-----GPLYTVCGTPTYVAP 621
Query: 268 EIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEG 302
EI AE G KVDIW++GV Y + G PF G
Sbjct: 622 EII--AETGYGLKVDIWAAGVITYILLCGFPPFRG 654
>BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 104 bits (250), Expect = 6e-22
Identities = 68/270 (25%), Positives = 128/270 (47%), Gaps = 10/270 (3%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
KY + +G+G++GK + +S + V E + ++E+ LL ++H
Sbjct: 3 KYDVIKAIGQGAFGKAY-LAKGKSDSKHCVIKEINFEKMPIQEKEAS-KKEVILLEKMKH 60
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
N++ + E ++++VME+C G L + G F + Q +F+Q+ GL +
Sbjct: 61 PNIVAFFNSF--QENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKH 118
Query: 212 LHGQGVVHKDIKPGNLLLTLD-QTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIA 270
+H + ++H+DIK N+ L+ + K+ DFG+A L+ + ++ T G+P + PEI
Sbjct: 119 IHDRKILHRDIKAQNIFLSKNGMVAKLGDFGIARVLN--NSMELARTCIGTPYYLSPEIC 176
Query: 271 NGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXX 330
K DIWS G LY + T ++PFEG+N+ +L+ I +
Sbjct: 177 QNKPY--NNKTDIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQAHFAPISPGFSRELHS 234
Query: 331 XXXHMLNRDPTLRPTVHEIRRHAWVQATPP 360
+ P RP+++ I + +++ P
Sbjct: 235 LISQLFQVSPRDRPSINSILKRPFLENLIP 264
>AL834322-1|CAD38990.1| 365|Homo sapiens hypothetical protein
protein.
Length = 365
Score = 104 bits (250), Expect = 6e-22
Identities = 63/193 (32%), Positives = 97/193 (50%), Gaps = 4/193 (2%)
Query: 165 DEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKP 224
D+ + +L M F + ++E K + QA YF L+ G++YLH Q ++H+DIKP
Sbjct: 65 DDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKP 124
Query: 225 GNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPE-IANGAEQFSGTKVDI 283
NLL+ D +KI DFGV+ + + + G+PAF PE ++ + FSG +D+
Sbjct: 125 SNLLVGEDGHIKIADFGVSN--EFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDV 182
Query: 284 WSSGVTLYNMTTGRYPFEGDNVYRLLEAI-SRXXXXXXXXXXXXXXXXXXXHMLNRDPTL 342
W+ GVTLY G+ PF + + L I S+ ML+++P
Sbjct: 183 WAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPES 242
Query: 343 RPTVHEIRRHAWV 355
R V EI+ H WV
Sbjct: 243 RIVVPEIKLHPWV 255
>AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 104 bits (250), Expect = 6e-22
Identities = 68/270 (25%), Positives = 128/270 (47%), Gaps = 10/270 (3%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
KY + +G+G++GK + +S + V E + ++E+ LL ++H
Sbjct: 3 KYDVIKAIGQGAFGKAY-LAKGKSDSKHCVIKEINFEKMPIQEKEAS-KKEVILLEKMKH 60
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
N++ + E ++++VME+C G L + G F + Q +F+Q+ GL +
Sbjct: 61 PNIVAFFNSF--QENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKH 118
Query: 212 LHGQGVVHKDIKPGNLLLTLD-QTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIA 270
+H + ++H+DIK N+ L+ + K+ DFG+A L+ + ++ T G+P + PEI
Sbjct: 119 IHDRKILHRDIKAQNIFLSKNGMVAKLGDFGIARVLN--NSMELARTCIGTPYYLSPEIC 176
Query: 271 NGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXX 330
K DIWS G LY + T ++PFEG+N+ +L+ I +
Sbjct: 177 QNKPY--NNKTDIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQAHFAPISPGFSRELHS 234
Query: 331 XXXHMLNRDPTLRPTVHEIRRHAWVQATPP 360
+ P RP+++ I + +++ P
Sbjct: 235 LISQLFQVSPRDRPSINSILKRPFLENLIP 264
>AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 758
Score = 104 bits (249), Expect = 8e-22
Identities = 68/224 (30%), Positives = 110/224 (49%), Gaps = 31/224 (13%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ KVK L L R V P Q + RE+++++IL
Sbjct: 57 IGNYRLQKTIGKGNFAKVK--LARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKIL 114
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLD 210
H N+ E+ D YLV + +++A F Q++ +
Sbjct: 115 NHPNIGEVFD----------YLVAH---------------GRMKEKEARAKFRQIVSAVQ 149
Query: 211 YLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIA 270
Y H + +VH+D+K NLLL D +KI DFG + + ++ D T GSP + PE+
Sbjct: 150 YCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLD---TFCGSPPYAAPELF 206
Query: 271 NGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
G +++ G +VD+WS GV LY + +G PF+G N+ L E + R
Sbjct: 207 QG-KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLR 249
>AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein.
Length = 870
Score = 104 bits (249), Expect = 8e-22
Identities = 68/224 (30%), Positives = 110/224 (49%), Gaps = 31/224 (13%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRIL 150
+G Y + +G+G++ KVK L L R V P Q + RE+++++IL
Sbjct: 169 IGNYRLQKTIGKGNFAKVK--LARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKIL 226
Query: 151 RHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLD 210
H N+ E+ D YLV + +++A F Q++ +
Sbjct: 227 NHPNIGEVFD----------YLVAH---------------GRMKEKEARAKFRQIVSAVQ 261
Query: 211 YLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIA 270
Y H + +VH+D+K NLLL D +KI DFG + + ++ D T GSP + PE+
Sbjct: 262 YCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLD---TFCGSPPYAAPELF 318
Query: 271 NGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
G +++ G +VD+WS GV LY + +G PF+G N+ L E + R
Sbjct: 319 QG-KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLR 361
>BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protein
kinase 2 protein.
Length = 370
Score = 103 bits (248), Expect = 1e-21
Identities = 79/281 (28%), Positives = 129/281 (45%), Gaps = 21/281 (7%)
Query: 86 KKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG--EQNVQRE 143
K+ K+ Y +G+ LG G + VK+ + + A G + ++RE
Sbjct: 15 KQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIERE 74
Query: 144 IQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYF 202
+ +LR + H NVI L DV N + + L++E G L D L + + +A +
Sbjct: 75 VSILRQVLHHNVITLHDVYEN--RTDVVLILELVSGGELFDFLAQK--ESLSEEEATSFI 130
Query: 203 LQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQT-----LKITDFGVAEALDMFSQEDICYT 257
Q+LDG++YLH + + H D+KP N++L LD+ +K+ DFG+A ++ + +
Sbjct: 131 KQILDGVNYLHTKKIAHFDLKPENIML-LDKNIPIPHIKLIDFGLAHEIEDGVEFKNIF- 188
Query: 258 GQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLL---EAISR 314
G+P F PEI N + G + D+WS GV Y + +G PF GD L A+S
Sbjct: 189 --GTPEFVAPEIVN--YEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSY 244
Query: 315 XXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+L ++ R T+ E RH W+
Sbjct: 245 DFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWI 285
>BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein
MGC42105 protein.
Length = 436
Score = 103 bits (248), Expect = 1e-21
Identities = 76/278 (27%), Positives = 128/278 (46%), Gaps = 13/278 (4%)
Query: 89 KMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLR 148
K +G Y + +G G++ +VK L SL + V ++ + REI +
Sbjct: 69 KRIGFYRIRGEIGSGNFSQVK--LGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSME 126
Query: 149 ILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDG 208
L H N+I L +V+ + K++LVME+ G S+ GK + ++ F Q++
Sbjct: 127 KLHHPNIIRLYEVV--ETLSKLHLVMEYAGGGELFGKISTEGK-LSEPESKLIFSQIVSA 183
Query: 209 LDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPE 268
+ ++H ++H+D+K N+ T + +K+ DFG + + + ++ T GSP + PE
Sbjct: 184 VKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFST---VSKKGEMLNTFCGSPPYAAPE 240
Query: 269 IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXX 328
+ E + G VDIW+ GV LY M TG PF + V +L ++I
Sbjct: 241 LFRD-EHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCH 299
Query: 329 XXXXXHMLNRDPTLRPTVHEIRRHAWVQATP---PFEP 363
+L + PT R + I W+Q P P EP
Sbjct: 300 RLIRG-VLQQIPTERYGIDCIMNDEWMQGVPYPTPLEP 336
>BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 3 protein.
Length = 506
Score = 103 bits (248), Expect = 1e-21
Identities = 68/253 (26%), Positives = 120/253 (47%), Gaps = 10/253 (3%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y++ ++GEGS+G+ +L + N QN ++E LL ++H
Sbjct: 4 YMVLRMIGEGSFGRA--LLVQHESSNQMFAMKEIRLPKSFSN-TQNSRKEAVLLAKMKHP 60
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
N++ + + + +Y+VME+C G L ++ GK FP+ ++F Q+ G++++
Sbjct: 61 NIVAFKESF--EAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHI 118
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANG 272
H + V+H+DIK N+ LT + +K+ DFG A L + T G+P + PPEI
Sbjct: 119 HKKRVLHRDIKSKNIFLTQNGKVKLGDFGSARLLS--NPMAFACTYVGTPYYVPPEIWEN 176
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXXX 332
K DIWS G LY + T ++PF+ ++ L+ + +
Sbjct: 177 LPY--NNKSDIWSLGCILYELCTLKHPFQANSWKNLILKVCQGCISPLPSHYSYELQFLV 234
Query: 333 XHMLNRDPTLRPT 345
M R+P+ RP+
Sbjct: 235 KQMFKRNPSHRPS 247
>AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 3 protein.
Length = 507
Score = 103 bits (248), Expect = 1e-21
Identities = 68/253 (26%), Positives = 120/253 (47%), Gaps = 10/253 (3%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y++ ++GEGS+G+ +L + N QN ++E LL ++H
Sbjct: 4 YMVLRMIGEGSFGRA--LLVQHESSNQMFAMKEIRLPKSFSN-TQNSRKEAVLLAKMKHP 60
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
N++ + + + +Y+VME+C G L ++ GK FP+ ++F Q+ G++++
Sbjct: 61 NIVAFKESF--EAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHI 118
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANG 272
H + V+H+DIK N+ LT + +K+ DFG A L + T G+P + PPEI
Sbjct: 119 HKKRVLHRDIKSKNIFLTQNGKVKLGDFGSARLLS--NPMAFACTYVGTPYYVPPEIWEN 176
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXXX 332
K DIWS G LY + T ++PF+ ++ L+ + +
Sbjct: 177 LPY--NNKSDIWSLGCILYELCTLKHPFQANSWKNLILKVCQGCISPLPSHYSYELQFLV 234
Query: 333 XHMLNRDPTLRPT 345
M R+P+ RP+
Sbjct: 235 KQMFKRNPSHRPS 247
>AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein.
Length = 347
Score = 103 bits (248), Expect = 1e-21
Identities = 69/231 (29%), Positives = 112/231 (48%), Gaps = 12/231 (5%)
Query: 85 KKKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREI 144
KK+ + + +G LG+G +G V + QS A+ E ++RE+
Sbjct: 124 KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKA-GVEHQLRREV 182
Query: 145 QLLRILRHKNVIELVDVIYNDEKQKMYLVMEFC-VGVLQDMLESSPGKKFPQRQAHDYFL 203
++ LRH N++ L Y + ++YL++E+ +G + L+ KF +++ Y
Sbjct: 183 EIQSHLRHPNILRLYG--YFHDATRVYLILEYAPLGTVYRELQKL--SKFDEQRTATYIT 238
Query: 204 QLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA 263
+L + L Y H + V+H+DIKP NLLL LKI DFG + + +C G+
Sbjct: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC----GTLD 294
Query: 264 FQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
+ PPE+ G + KVD+WS GV Y G+ PFE + + ISR
Sbjct: 295 YLPPEMIEG--RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR 343
>AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protein
kinase 2 protein.
Length = 370
Score = 103 bits (248), Expect = 1e-21
Identities = 79/281 (28%), Positives = 129/281 (45%), Gaps = 21/281 (7%)
Query: 86 KKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG--EQNVQRE 143
K+ K+ Y +G+ LG G + VK+ + + A G + ++RE
Sbjct: 15 KQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIERE 74
Query: 144 IQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYF 202
+ +LR + H NVI L DV N + + L++E G L D L + + +A +
Sbjct: 75 VSILRQVLHHNVITLHDVYEN--RTDVVLILELVSGGELFDFLAQK--ESLSEEEATSFI 130
Query: 203 LQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQT-----LKITDFGVAEALDMFSQEDICYT 257
Q+LDG++YLH + + H D+KP N++L LD+ +K+ DFG+A ++ + +
Sbjct: 131 KQILDGVNYLHTKKIAHFDLKPENIML-LDKNIPIPHIKLIDFGLAHEIEDGVEFKNIF- 188
Query: 258 GQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLL---EAISR 314
G+P F PEI N + G + D+WS GV Y + +G PF GD L A+S
Sbjct: 189 --GTPEFVAPEIVN--YEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSY 244
Query: 315 XXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+L ++ R T+ E RH W+
Sbjct: 245 DFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWI 285
>BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase 12
protein.
Length = 344
Score = 103 bits (247), Expect = 1e-21
Identities = 74/269 (27%), Positives = 123/269 (45%), Gaps = 15/269 (5%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG-EQNVQREIQLLRI 149
+ + +G LG+G +G V + +S V G E ++REI++
Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKS--HFIVALKVLFKSQIEKEGVEHQLRREIEIQAH 131
Query: 150 LRHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDG 208
L H N++ L + Y +++++YL++E+ G L L+ S F +++ +L D
Sbjct: 132 LHHPNILRLYNYFY--DRRRIYLILEYAPRGELYKELQKSC--TFDEQRTATIMEELADA 187
Query: 209 LDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPE 268
L Y HG+ V+H+DIKP NLLL L LKI DFG + ++ +C G+ + PPE
Sbjct: 188 LMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMC----GTLDYLPPE 243
Query: 269 IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXX 328
+ G + KVD+W GV Y + G PFE + I +
Sbjct: 244 MIEG--RMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVK-VDLKFPASVPTGA 300
Query: 329 XXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +P+ R + ++ H WV+A
Sbjct: 301 QDLISKLLRHNPSERLPLAQVSAHPWVRA 329
>BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 103 bits (247), Expect = 1e-21
Identities = 74/269 (27%), Positives = 123/269 (45%), Gaps = 15/269 (5%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG-EQNVQREIQLLRI 149
+ + +G LG+G +G V + +S V G E ++REI++
Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKS--HFIVALKVLFKSQIEKEGVEHQLRREIEIQAH 131
Query: 150 LRHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDG 208
L H N++ L + Y +++++YL++E+ G L L+ S F +++ +L D
Sbjct: 132 LHHPNILRLYNYFY--DRRRIYLILEYAPRGELYKELQKSC--TFDEQRTATIMEELADA 187
Query: 209 LDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPE 268
L Y HG+ V+H+DIKP NLLL L LKI DFG + ++ +C G+ + PPE
Sbjct: 188 LMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMC----GTLDYLPPE 243
Query: 269 IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXX 328
+ G + KVD+W GV Y + G PFE + I +
Sbjct: 244 MIEG--RMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVK-VDLKFPASVPTGA 300
Query: 329 XXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +P+ R + ++ H WV+A
Sbjct: 301 QDLISKLLRHNPSERLPLAQVSAHPWVRA 329
>BC031647-1|AAH31647.1| 520|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase 1,
alpha protein.
Length = 520
Score = 103 bits (247), Expect = 1e-21
Identities = 61/174 (35%), Positives = 90/174 (51%), Gaps = 4/174 (2%)
Query: 184 MLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVA 243
++E K F + QA Y ++ GL+YLH Q +VH+DIKP NLLL D +KI DFGV+
Sbjct: 276 VMEVPCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVS 335
Query: 244 EALDMFSQEDICYTGQGSPAFQPPE-IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEG 302
+ + + G+PAF PE I++ + FSG +D+W++GVTLY G+ PF
Sbjct: 336 NQFE--GNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFID 393
Query: 303 DNVYRLLEAI-SRXXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
D + L I + ML+++P R V +I+ H WV
Sbjct: 394 DFILALHRKIKNEPVVFPEGPEISEELKDLILKMLDKNPETRIGVPDIKLHPWV 447
Score = 32.3 bits (70), Expect = 3.9
Identities = 12/38 (31%), Positives = 26/38 (68%)
Query: 138 QNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVME 175
+ V +EI +L+ L H NV++L++V+ + + +YL ++
Sbjct: 194 ERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLALQ 231
>BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 103 bits (247), Expect = 1e-21
Identities = 74/269 (27%), Positives = 123/269 (45%), Gaps = 15/269 (5%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG-EQNVQREIQLLRI 149
+ + +G LG+G +G V + +S V G E ++REI++
Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKS--HFIVALKVLFKSQIEKEGVEHQLRREIEIQAH 131
Query: 150 LRHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDG 208
L H N++ L + Y +++++YL++E+ G L L+ S F +++ +L D
Sbjct: 132 LHHPNILRLYNYFY--DRRRIYLILEYAPRGELYKELQKSC--TFDEQRTATIMEELADA 187
Query: 209 LDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPE 268
L Y HG+ V+H+DIKP NLLL L LKI DFG + ++ +C G+ + PPE
Sbjct: 188 LMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMC----GTLDYLPPE 243
Query: 269 IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXX 328
+ G + KVD+W GV Y + G PFE + I +
Sbjct: 244 MIEG--RMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVK-VDLKFPASVPTGA 300
Query: 329 XXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +P+ R + ++ H WV+A
Sbjct: 301 QDLISKLLRHNPSERLPLAQVSAHPWVRA 329
>AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2
protein.
Length = 344
Score = 103 bits (247), Expect = 1e-21
Identities = 74/269 (27%), Positives = 123/269 (45%), Gaps = 15/269 (5%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG-EQNVQREIQLLRI 149
+ + +G LG+G +G V + +S V G E ++REI++
Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKS--HFIVALKVLFKSQIEKEGVEHQLRREIEIQAH 131
Query: 150 LRHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDG 208
L H N++ L + Y +++++YL++E+ G L L+ S F +++ +L D
Sbjct: 132 LHHPNILRLYNYFY--DRRRIYLILEYAPRGELYKELQKSC--TFDEQRTATIMEELADA 187
Query: 209 LDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPE 268
L Y HG+ V+H+DIKP NLLL L LKI DFG + ++ +C G+ + PPE
Sbjct: 188 LMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMC----GTLDYLPPE 243
Query: 269 IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXX 328
+ G + KVD+W GV Y + G PFE + I +
Sbjct: 244 MIEG--RMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVK-VDLKFPASVPTGA 300
Query: 329 XXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +P+ R + ++ H WV+A
Sbjct: 301 QDLISKLLRHNPSERLPLAQVSAHPWVRA 329
>AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like
midbody-associated protein kinase-1 protein.
Length = 344
Score = 103 bits (247), Expect = 1e-21
Identities = 74/269 (27%), Positives = 123/269 (45%), Gaps = 15/269 (5%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG-EQNVQREIQLLRI 149
+ + +G LG+G +G V + +S V G E ++REI++
Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKS--HFIVALKVLFKSQIEKEGVEHQLRREIEIQAH 131
Query: 150 LRHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDG 208
L H N++ L + Y +++++YL++E+ G L L+ S F +++ +L D
Sbjct: 132 LHHPNILRLYNYFY--DRRRIYLILEYAPRGELYKELQKSC--TFDEQRTATIMEELADA 187
Query: 209 LDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPE 268
L Y HG+ V+H+DIKP NLLL L LKI DFG + ++ +C G+ + PPE
Sbjct: 188 LMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMC----GTLDYLPPE 243
Query: 269 IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXX 328
+ G + KVD+W GV Y + G PFE + I +
Sbjct: 244 MIEG--RMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVK-VDLKFPASVPTGA 300
Query: 329 XXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +P+ R + ++ H WV+A
Sbjct: 301 QDLISKLLRHNPSERLPLAQVSAHPWVRA 329
>Y00272-1|CAA68376.1| 297|Homo sapiens protein ( Human cell cycle
control gene CDC2. ).
Length = 297
Score = 103 bits (246), Expect = 2e-21
Identities = 68/213 (31%), Positives = 104/213 (48%), Gaps = 10/213 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y + +GEG+YG V + + V REI LL+ LRH
Sbjct: 4 YTKIEKIGEGTYGVVYK--GRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLES-SPGKKFPQRQAHDYFLQLLDGLDYL 212
N++ L DV+ D + +YL+ EF L+ L+S PG+ Y Q+L G+ +
Sbjct: 62 NIVSLQDVLMQDSR--LYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIAN 271
H + V+H+D+KP NLL+ T+K+ DFG+A A F YT + ++ PE+
Sbjct: 120 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARA---FGIPIRVYTHEVVTLWYRSPEVLL 176
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDN 304
G+ ++S T VDIWS G + T + F GD+
Sbjct: 177 GSARYS-TPVDIWSIGTIFAELATKKPLFHGDS 208
>X05360-1|CAA28963.1| 297|Homo sapiens protein ( Human CDC2 gene
involved in cell cycle control. ).
Length = 297
Score = 103 bits (246), Expect = 2e-21
Identities = 68/213 (31%), Positives = 104/213 (48%), Gaps = 10/213 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y + +GEG+YG V + + V REI LL+ LRH
Sbjct: 4 YTKIEKIGEGTYGVVYK--GRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLES-SPGKKFPQRQAHDYFLQLLDGLDYL 212
N++ L DV+ D + +YL+ EF L+ L+S PG+ Y Q+L G+ +
Sbjct: 62 NIVSLQDVLMQDSR--LYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIAN 271
H + V+H+D+KP NLL+ T+K+ DFG+A A F YT + ++ PE+
Sbjct: 120 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARA---FGIPIRVYTHEVVTLWYRSPEVLL 176
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDN 304
G+ ++S T VDIWS G + T + F GD+
Sbjct: 177 GSARYS-TPVDIWSIGTIFAELATKKPLFHGDS 208
>BT007004-1|AAP35650.1| 297|Homo sapiens cell division cycle 2, G1
to S and G2 to M protein.
Length = 297
Score = 103 bits (246), Expect = 2e-21
Identities = 68/213 (31%), Positives = 104/213 (48%), Gaps = 10/213 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y + +GEG+YG V + + V REI LL+ LRH
Sbjct: 4 YTKIEKIGEGTYGVVYK--GRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLES-SPGKKFPQRQAHDYFLQLLDGLDYL 212
N++ L DV+ D + +YL+ EF L+ L+S PG+ Y Q+L G+ +
Sbjct: 62 NIVSLQDVLMQDSR--LYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIAN 271
H + V+H+D+KP NLL+ T+K+ DFG+A A F YT + ++ PE+
Sbjct: 120 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARA---FGIPIRVYTHEVVTLWYRSPEVLL 176
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDN 304
G+ ++S T VDIWS G + T + F GD+
Sbjct: 177 GSARYS-TPVDIWSIGTIFAELATKKPLFHGDS 208
>BC107750-1|AAI07751.1| 225|Homo sapiens CDC2 protein protein.
Length = 225
Score = 103 bits (246), Expect = 2e-21
Identities = 68/213 (31%), Positives = 104/213 (48%), Gaps = 10/213 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y + +GEG+YG V + + V REI LL+ LRH
Sbjct: 4 YTKIEKIGEGTYGVVYK--GRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLES-SPGKKFPQRQAHDYFLQLLDGLDYL 212
N++ L DV+ D + +YL+ EF L+ L+S PG+ Y Q+L G+ +
Sbjct: 62 NIVSLQDVLMQDSR--LYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIAN 271
H + V+H+D+KP NLL+ T+K+ DFG+A A F YT + ++ PE+
Sbjct: 120 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARA---FGIPIRVYTHEVVTLWYRSPEVLL 176
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDN 304
G+ ++S T VDIWS G + T + F GD+
Sbjct: 177 GSARYS-TPVDIWSIGTIFAELATKKPLFHGDS 208
>BC014563-1|AAH14563.1| 297|Homo sapiens cell division cycle 2, G1
to S and G2 to M protein.
Length = 297
Score = 103 bits (246), Expect = 2e-21
Identities = 68/213 (31%), Positives = 104/213 (48%), Gaps = 10/213 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y + +GEG+YG V + + V REI LL+ LRH
Sbjct: 4 YTKIEKIGEGTYGVVYK--GRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLES-SPGKKFPQRQAHDYFLQLLDGLDYL 212
N++ L DV+ D + +YL+ EF L+ L+S PG+ Y Q+L G+ +
Sbjct: 62 NIVSLQDVLMQDSR--LYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIAN 271
H + V+H+D+KP NLL+ T+K+ DFG+A A F YT + ++ PE+
Sbjct: 120 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARA---FGIPIRVYTHEVVTLWYRSPEVLL 176
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDN 304
G+ ++S T VDIWS G + T + F GD+
Sbjct: 177 GSARYS-TPVDIWSIGTIFAELATKKPLFHGDS 208
>BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein.
Length = 371
Score = 103 bits (246), Expect = 2e-21
Identities = 74/269 (27%), Positives = 123/269 (45%), Gaps = 15/269 (5%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG-EQNVQREIQLLRI 149
+ + +G LG+G +G V + +S V G E ++REI++
Sbjct: 101 IDDFEIGRPLGKGKFGNVYLAREKKS--HFIVALKVLFKSQIEKEGVEHQLRREIEIQAH 158
Query: 150 LRHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDG 208
L H N++ L + Y +++++YL++E+ G L L+ S F +++ +L D
Sbjct: 159 LHHPNILRLYNYFY--DRRRIYLILEYAPRGELYKELQKSC--TFDEQRTATIMEELADA 214
Query: 209 LDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPE 268
L Y HG+ V+H+DIKP NLLL L LKI DFG + ++ +C G+ + PPE
Sbjct: 215 LMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMC----GTLDYLPPE 270
Query: 269 IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXX 328
+ G + KVD+W GV Y + G PFE + I +
Sbjct: 271 MIEG--RMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVK-VDLKFPASVPMGA 327
Query: 329 XXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +P+ R + ++ H WV+A
Sbjct: 328 QDLISKLLRHNPSERLPLAQVSAHPWVRA 356
>BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 103 bits (246), Expect = 2e-21
Identities = 74/269 (27%), Positives = 123/269 (45%), Gaps = 15/269 (5%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG-EQNVQREIQLLRI 149
+ + +G LG+G +G V + +S V G E ++REI++
Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKS--HFIVALKVLFKSQIEKEGVEHQLRREIEIQAH 131
Query: 150 LRHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDG 208
L H N++ L + Y +++++YL++E+ G L L+ S F +++ +L D
Sbjct: 132 LHHPNILRLYNYFY--DRRRIYLILEYAPRGELYKELQKSC--TFDEQRTATIMEELADA 187
Query: 209 LDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPE 268
L Y HG+ V+H+DIKP NLLL L LKI DFG + ++ +C G+ + PPE
Sbjct: 188 LMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMC----GTLDYLPPE 243
Query: 269 IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXX 328
+ G + KVD+W GV Y + G PFE + I +
Sbjct: 244 MIEG--RMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVK-VDLKFPASVPMGA 300
Query: 329 XXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +P+ R + ++ H WV+A
Sbjct: 301 QDLISKLLRHNPSERLPLAQVSAHPWVRA 329
>AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens
cDNA FLJ24002 fis, clone KAIA4350, highly similar to
Homo sapiens serine/threonine protein kinase SSTK
(SSTK). ).
Length = 406
Score = 103 bits (246), Expect = 2e-21
Identities = 69/215 (32%), Positives = 108/215 (50%), Gaps = 12/215 (5%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQN-VQREIQLLRILRH 152
Y +G +GEGSY KVK + + + V P+ + RE+ +LR +RH
Sbjct: 12 YKLGRTIGEGSYSKVK--VATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRH 69
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLES-SPGKKFPQRQAHDYFLQLLDGLDY 211
+++ + + I K+Y+VME D+L++ + P QA D F Q+ + Y
Sbjct: 70 PHIVHVFEFI-EVCNGKLYIVME---AAATDLLQAVQRNGRIPGVQARDLFAQIAGAVRY 125
Query: 212 LHGQGVVHKDIKPGNLLLTLDQ-TLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIA 270
LH +VH+D+K N+LL+ D+ +K+TDFG D+ T GS A+ PE+
Sbjct: 126 LHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGR--QAHGYPDLSTTYCGSAAYASPEVL 183
Query: 271 NGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNV 305
G + K D+WS GV LY M TG PF+ ++
Sbjct: 184 LGI-PYDPKKYDVWSMGVVLYVMVTGCMPFDDSDI 217
>AF512554-1|AAM34793.1| 297|Homo sapiens cell division cycle 2, G1
to S and G2 to M protein.
Length = 297
Score = 103 bits (246), Expect = 2e-21
Identities = 68/213 (31%), Positives = 104/213 (48%), Gaps = 10/213 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y + +GEG+YG V + + V REI LL+ LRH
Sbjct: 4 YTKIEKIGEGTYGVVYK--GRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLES-SPGKKFPQRQAHDYFLQLLDGLDYL 212
N++ L DV+ D + +YL+ EF L+ L+S PG+ Y Q+L G+ +
Sbjct: 62 NIVSLQDVLMQDSR--LYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIAN 271
H + V+H+D+KP NLL+ T+K+ DFG+A A F YT + ++ PE+
Sbjct: 120 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARA---FGIPIRVYTHEVVTLWYRSPEVLL 176
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDN 304
G+ ++S T VDIWS G + T + F GD+
Sbjct: 177 GSARYS-TPVDIWSIGTIFAELATKKPLFHGDS 208
>BC035745-1|AAH35745.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 102 bits (245), Expect = 2e-21
Identities = 67/226 (29%), Positives = 113/226 (50%), Gaps = 16/226 (7%)
Query: 137 EQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKF-PQ 195
E +++ EI +LR ++H+N++ L D+ + +YLVM+ G ++ + K F +
Sbjct: 63 ESSIENEIAVLRKIKHENIVALEDIY--ESPNHLYLVMQLVSG--GELFDRIVEKGFYTE 118
Query: 196 RQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLL-LTLDQTLK--ITDFGVAEALDMFSQE 252
+ A Q+LD + YLH G+VH+D+KP NLL + D+ K I+DFG+++ M +
Sbjct: 119 KDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK---MEGKG 175
Query: 253 DICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312
D+ T G+P + PE+ A++ VD WS GV Y + G PF +N +L E I
Sbjct: 176 DVMSTACGTPGYVAPEVL--AQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQI 233
Query: 313 SRXXXXXXX---XXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ +++ +DP R T + RH W+
Sbjct: 234 LKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AL731559-2|CAI14675.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 102 bits (245), Expect = 2e-21
Identities = 67/226 (29%), Positives = 113/226 (50%), Gaps = 16/226 (7%)
Query: 137 EQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKF-PQ 195
E +++ EI +LR ++H+N++ L D+ + +YLVM+ G ++ + K F +
Sbjct: 63 ESSIENEIAVLRKIKHENIVALEDIY--ESPNHLYLVMQLVSG--GELFDRIVEKGFYTE 118
Query: 196 RQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLL-LTLDQTLK--ITDFGVAEALDMFSQE 252
+ A Q+LD + YLH G+VH+D+KP NLL + D+ K I+DFG+++ M +
Sbjct: 119 KDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK---MEGKG 175
Query: 253 DICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312
D+ T G+P + PE+ A++ VD WS GV Y + G PF +N +L E I
Sbjct: 176 DVMSTACGTPGYVAPEVL--AQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQI 233
Query: 313 SRXXXXXXX---XXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ +++ +DP R T + RH W+
Sbjct: 234 LKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AL731559-1|CAI14674.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 102 bits (245), Expect = 2e-21
Identities = 67/226 (29%), Positives = 113/226 (50%), Gaps = 16/226 (7%)
Query: 137 EQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKF-PQ 195
E +++ EI +LR ++H+N++ L D+ + +YLVM+ G ++ + K F +
Sbjct: 63 ESSIENEIAVLRKIKHENIVALEDIY--ESPNHLYLVMQLVSG--GELFDRIVEKGFYTE 118
Query: 196 RQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLL-LTLDQTLK--ITDFGVAEALDMFSQE 252
+ A Q+LD + YLH G+VH+D+KP NLL + D+ K I+DFG+++ M +
Sbjct: 119 KDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK---MEGKG 175
Query: 253 DICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312
D+ T G+P + PE+ A++ VD WS GV Y + G PF +N +L E I
Sbjct: 176 DVMSTACGTPGYVAPEVL--AQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQI 233
Query: 313 SRXXXXXXX---XXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ +++ +DP R T + RH W+
Sbjct: 234 LKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AL512783-2|CAH74036.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 102 bits (245), Expect = 2e-21
Identities = 67/226 (29%), Positives = 113/226 (50%), Gaps = 16/226 (7%)
Query: 137 EQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKF-PQ 195
E +++ EI +LR ++H+N++ L D+ + +YLVM+ G ++ + K F +
Sbjct: 63 ESSIENEIAVLRKIKHENIVALEDIY--ESPNHLYLVMQLVSG--GELFDRIVEKGFYTE 118
Query: 196 RQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLL-LTLDQTLK--ITDFGVAEALDMFSQE 252
+ A Q+LD + YLH G+VH+D+KP NLL + D+ K I+DFG+++ M +
Sbjct: 119 KDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK---MEGKG 175
Query: 253 DICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312
D+ T G+P + PE+ A++ VD WS GV Y + G PF +N +L E I
Sbjct: 176 DVMSTACGTPGYVAPEVL--AQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQI 233
Query: 313 SRXXXXXXX---XXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ +++ +DP R T + RH W+
Sbjct: 234 LKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AL512783-1|CAH74035.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 102 bits (245), Expect = 2e-21
Identities = 67/226 (29%), Positives = 113/226 (50%), Gaps = 16/226 (7%)
Query: 137 EQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKF-PQ 195
E +++ EI +LR ++H+N++ L D+ + +YLVM+ G ++ + K F +
Sbjct: 63 ESSIENEIAVLRKIKHENIVALEDIY--ESPNHLYLVMQLVSG--GELFDRIVEKGFYTE 118
Query: 196 RQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLL-LTLDQTLK--ITDFGVAEALDMFSQE 252
+ A Q+LD + YLH G+VH+D+KP NLL + D+ K I+DFG+++ M +
Sbjct: 119 KDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK---MEGKG 175
Query: 253 DICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312
D+ T G+P + PE+ A++ VD WS GV Y + G PF +N +L E I
Sbjct: 176 DVMSTACGTPGYVAPEVL--AQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQI 233
Query: 313 SRXXXXXXX---XXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ +++ +DP R T + RH W+
Sbjct: 234 LKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AL512284-2|CAH71694.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 102 bits (245), Expect = 2e-21
Identities = 67/226 (29%), Positives = 113/226 (50%), Gaps = 16/226 (7%)
Query: 137 EQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKF-PQ 195
E +++ EI +LR ++H+N++ L D+ + +YLVM+ G ++ + K F +
Sbjct: 63 ESSIENEIAVLRKIKHENIVALEDIY--ESPNHLYLVMQLVSG--GELFDRIVEKGFYTE 118
Query: 196 RQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLL-LTLDQTLK--ITDFGVAEALDMFSQE 252
+ A Q+LD + YLH G+VH+D+KP NLL + D+ K I+DFG+++ M +
Sbjct: 119 KDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK---MEGKG 175
Query: 253 DICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312
D+ T G+P + PE+ A++ VD WS GV Y + G PF +N +L E I
Sbjct: 176 DVMSTACGTPGYVAPEVL--AQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQI 233
Query: 313 SRXXXXXXX---XXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ +++ +DP R T + RH W+
Sbjct: 234 LKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AL512284-1|CAH71693.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 102 bits (245), Expect = 2e-21
Identities = 67/226 (29%), Positives = 113/226 (50%), Gaps = 16/226 (7%)
Query: 137 EQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKF-PQ 195
E +++ EI +LR ++H+N++ L D+ + +YLVM+ G ++ + K F +
Sbjct: 63 ESSIENEIAVLRKIKHENIVALEDIY--ESPNHLYLVMQLVSG--GELFDRIVEKGFYTE 118
Query: 196 RQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLL-LTLDQTLK--ITDFGVAEALDMFSQE 252
+ A Q+LD + YLH G+VH+D+KP NLL + D+ K I+DFG+++ M +
Sbjct: 119 KDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK---MEGKG 175
Query: 253 DICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312
D+ T G+P + PE+ A++ VD WS GV Y + G PF +N +L E I
Sbjct: 176 DVMSTACGTPGYVAPEVL--AQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQI 233
Query: 313 SRXXXXXXX---XXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ +++ +DP R T + RH W+
Sbjct: 234 LKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AL391314-2|CAI14410.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 102 bits (245), Expect = 2e-21
Identities = 67/226 (29%), Positives = 113/226 (50%), Gaps = 16/226 (7%)
Query: 137 EQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKF-PQ 195
E +++ EI +LR ++H+N++ L D+ + +YLVM+ G ++ + K F +
Sbjct: 63 ESSIENEIAVLRKIKHENIVALEDIY--ESPNHLYLVMQLVSG--GELFDRIVEKGFYTE 118
Query: 196 RQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLL-LTLDQTLK--ITDFGVAEALDMFSQE 252
+ A Q+LD + YLH G+VH+D+KP NLL + D+ K I+DFG+++ M +
Sbjct: 119 KDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK---MEGKG 175
Query: 253 DICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312
D+ T G+P + PE+ A++ VD WS GV Y + G PF +N +L E I
Sbjct: 176 DVMSTACGTPGYVAPEVL--AQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQI 233
Query: 313 SRXXXXXXX---XXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ +++ +DP R T + RH W+
Sbjct: 234 LKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AL391314-1|CAI14409.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 102 bits (245), Expect = 2e-21
Identities = 67/226 (29%), Positives = 113/226 (50%), Gaps = 16/226 (7%)
Query: 137 EQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKF-PQ 195
E +++ EI +LR ++H+N++ L D+ + +YLVM+ G ++ + K F +
Sbjct: 63 ESSIENEIAVLRKIKHENIVALEDIY--ESPNHLYLVMQLVSG--GELFDRIVEKGFYTE 118
Query: 196 RQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLL-LTLDQTLK--ITDFGVAEALDMFSQE 252
+ A Q+LD + YLH G+VH+D+KP NLL + D+ K I+DFG+++ M +
Sbjct: 119 KDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK---MEGKG 175
Query: 253 DICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312
D+ T G+P + PE+ A++ VD WS GV Y + G PF +N +L E I
Sbjct: 176 DVMSTACGTPGYVAPEVL--AQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQI 233
Query: 313 SRXXXXXXX---XXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ +++ +DP R T + RH W+
Sbjct: 234 LKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kinase
protein.
Length = 357
Score = 102 bits (245), Expect = 2e-21
Identities = 67/226 (29%), Positives = 113/226 (50%), Gaps = 16/226 (7%)
Query: 137 EQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKF-PQ 195
E +++ EI +LR ++H+N++ L D+ + +YLVM+ G ++ + K F +
Sbjct: 63 ESSIENEIAVLRKIKHENIVALEDIY--ESPNHLYLVMQLVSG--GELFDRIVEKGFYTE 118
Query: 196 RQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLL-LTLDQTLK--ITDFGVAEALDMFSQE 252
+ A Q+LD + YLH G+VH+D+KP NLL + D+ K I+DFG+++ M +
Sbjct: 119 KDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK---MEGKG 175
Query: 253 DICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312
D+ T G+P + PE+ A++ VD WS GV Y + G PF +N +L E I
Sbjct: 176 DVMSTACGTPGYVAPEVL--AQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQI 233
Query: 313 SRXXXXXXX---XXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ +++ +DP R T + RH W+
Sbjct: 234 LKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related protein
1 protein.
Length = 370
Score = 102 bits (245), Expect = 2e-21
Identities = 78/281 (27%), Positives = 129/281 (45%), Gaps = 21/281 (7%)
Query: 86 KKCKMVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG--EQNVQRE 143
K+ K+ Y +G+ LG G + VK+ + + A G + ++RE
Sbjct: 15 KQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIERE 74
Query: 144 IQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVG-VLQDMLESSPGKKFPQRQAHDYF 202
+ +LR + H NVI L DV N + + L++E G L D L + + +A +
Sbjct: 75 VSILRQVLHHNVITLHDVYEN--RTDVVLILELVSGGELFDFLAQK--ESLSEEEATSFI 130
Query: 203 LQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQT-----LKITDFGVAEALDMFSQEDICYT 257
Q+LDG++YLH + + H D+KP N++L LD+ +K+ DFG+A ++ + +
Sbjct: 131 KQILDGVNYLHTKKIAHFDLKPENIML-LDKNIPIPHIKLIDFGLAHEIEDGVEFKNIF- 188
Query: 258 GQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLL---EAISR 314
G+P F PEI N + G + D+WS GV Y + +G PF GD L ++S
Sbjct: 189 --GTPEFVAPEIVN--YEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITSVSY 244
Query: 315 XXXXXXXXXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+L ++ R T+ E RH W+
Sbjct: 245 DFDEEFFSHTSELAKDFIRKLLVKETRKRLTIQEALRHPWI 285
>AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta
protein.
Length = 385
Score = 102 bits (245), Expect = 2e-21
Identities = 67/226 (29%), Positives = 113/226 (50%), Gaps = 16/226 (7%)
Query: 137 EQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKF-PQ 195
E +++ EI +LR ++H+N++ L D+ + +YLVM+ G ++ + K F +
Sbjct: 63 ESSIENEIAVLRKIKHENIVALEDIY--ESPNHLYLVMQLVSG--GELFDRIVEKGFYTE 118
Query: 196 RQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLL-LTLDQTLK--ITDFGVAEALDMFSQE 252
+ A Q+LD + YLH G+VH+D+KP NLL + D+ K I+DFG+++ M +
Sbjct: 119 KDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK---MEGKG 175
Query: 253 DICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAI 312
D+ T G+P + PE+ A++ VD WS GV Y + G PF +N +L E I
Sbjct: 176 DVMSTACGTPGYVAPEVL--AQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQI 233
Query: 313 SRXXXXXXX---XXXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
+ +++ +DP R T + RH W+
Sbjct: 234 LKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein.
Length = 608
Score = 102 bits (244), Expect = 3e-21
Identities = 74/274 (27%), Positives = 132/274 (48%), Gaps = 26/274 (9%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y G V+G+G++ VKE ++ R E V EI +++ L H
Sbjct: 316 YETGRVIGDGNFAVVKECRHRET---RQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHP 372
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVG--VLQDMLESSPGKKFPQRQAHDYFLQLLDGLDY 211
N+++L +V D ++YL++E+ G + ++ES KFP+ A + L L +
Sbjct: 373 NIVKLHEVYETD--MEIYLILEYVQGGDLFDAIIESV---KFPEPDAALMIMDLCKALVH 427
Query: 212 LHGQGVVHKDIKPGNLLLTLDQ----TLKITDFGVAEALDMFSQEDICYTGQGSPAFQPP 267
+H + +VH+D+KP NLL+ ++ TLK+ DFG+A+ + +T G+P + P
Sbjct: 428 MHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHV-----VRPIFTVCGTPTYVAP 482
Query: 268 EIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPF-----EGDNVYRLLEAISRXXXXXXXX 322
EI +E+ G +VD+W++GV LY + G PF + D ++ +++
Sbjct: 483 EIL--SEKGYGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWD 540
Query: 323 XXXXXXXXXXXHMLNRDPTLRPTVHEIRRHAWVQ 356
+L DP R T H++ +H W++
Sbjct: 541 NISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWIE 574
>L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein.
Length = 370
Score = 101 bits (243), Expect = 4e-21
Identities = 74/269 (27%), Positives = 124/269 (46%), Gaps = 19/269 (7%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y DVLG G++ +V D ++ + + E +++ EI +L ++H
Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRT---QKLVAIKCIAKEALEGKEGSMENEIAVLHKIKHP 76
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKF-PQRQAHDYFLQLLDGLDYL 212
N++ L D+ + +YL+M+ G ++ + K F +R A Q+LD + YL
Sbjct: 77 NIVALDDIY--ESGGHLYLIMQLVSG--GELFDRIVEKGFYTERDASRLIFQVLDAVKYL 132
Query: 213 HGQGVVHKDIKPGNLL---LTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
H G+VH+D+KP NLL L D + I+DFG+++ D S + T G+P + PE+
Sbjct: 133 HDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGS---VLSTACGTPGYVAPEV 189
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXX---XXXXX 326
A++ VD WS GV Y + G PF +N +L E I +
Sbjct: 190 L--AQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISD 247
Query: 327 XXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
H++ +DP R T + +H W+
Sbjct: 248 SAKDFIRHLMEKDPEKRFTCEQALQHPWI 276
>BC106755-1|AAI06756.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 101 bits (243), Expect = 4e-21
Identities = 74/269 (27%), Positives = 124/269 (46%), Gaps = 19/269 (7%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y DVLG G++ +V D ++ + + E +++ EI +L ++H
Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRT---QKLVAIKCIAKEALEGKEGSMENEIAVLHKIKHP 76
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKF-PQRQAHDYFLQLLDGLDYL 212
N++ L D+ + +YL+M+ G ++ + K F +R A Q+LD + YL
Sbjct: 77 NIVALDDIY--ESGGHLYLIMQLVSG--GELFDRIVEKGFYTERDASRLIFQVLDAVKYL 132
Query: 213 HGQGVVHKDIKPGNLL---LTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
H G+VH+D+KP NLL L D + I+DFG+++ D S + T G+P + PE+
Sbjct: 133 HDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGS---VLSTACGTPGYVAPEV 189
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXX---XXXXX 326
A++ VD WS GV Y + G PF +N +L E I +
Sbjct: 190 L--AQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISD 247
Query: 327 XXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
H++ +DP R T + +H W+
Sbjct: 248 SAKDFIRHLMEKDPEKRFTCEQALQHPWI 276
>BC106754-1|AAI06755.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 101 bits (243), Expect = 4e-21
Identities = 74/269 (27%), Positives = 124/269 (46%), Gaps = 19/269 (7%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y DVLG G++ +V D ++ + + E +++ EI +L ++H
Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRT---QKLVAIKCIAKEALEGKEGSMENEIAVLHKIKHP 76
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKF-PQRQAHDYFLQLLDGLDYL 212
N++ L D+ + +YL+M+ G ++ + K F +R A Q+LD + YL
Sbjct: 77 NIVALDDIY--ESGGHLYLIMQLVSG--GELFDRIVEKGFYTERDASRLIFQVLDAVKYL 132
Query: 213 HGQGVVHKDIKPGNLL---LTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEI 269
H G+VH+D+KP NLL L D + I+DFG+++ D S + T G+P + PE+
Sbjct: 133 HDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGS---VLSTACGTPGYVAPEV 189
Query: 270 ANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXX---XXXXX 326
A++ VD WS GV Y + G PF +N +L E I +
Sbjct: 190 L--AQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISD 247
Query: 327 XXXXXXXHMLNRDPTLRPTVHEIRRHAWV 355
H++ +DP R T + +H W+
Sbjct: 248 SAKDFIRHLMEKDPEKRFTCEQALQHPWI 276
>U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine
protein kinase PRK protein.
Length = 607
Score = 101 bits (242), Expect = 6e-21
Identities = 67/261 (25%), Positives = 120/261 (45%), Gaps = 13/261 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y+ G +LG+G + + E D+++ AV P+ + + EI+L R L+H+
Sbjct: 23 YLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAK-PHQREKILNEIELHRDLQHR 81
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
+++ + ++ +Y+ +E C + + + + Y Q+L GL YLH
Sbjct: 82 HIVRFSH--HFEDADNIYIFLELCSRKSLAHIWKARHTLL-EPEVRYYLRQILSGLKYLH 138
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQ--EDICYTGQGSPAFQPPEIAN 271
+G++H+D+K GN +T + LK+ DFG+A L+ Q + IC G+P + PE+
Sbjct: 139 QRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTIC----GTPNYVAPEVL- 193
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXX 331
Q G + D+WS G +Y + G PFE ++ I +
Sbjct: 194 -LRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLL 252
Query: 332 XXHMLNRDPTLRPTVHEIRRH 352
+L P RP++ +I RH
Sbjct: 253 AA-ILRASPRDRPSIDQILRH 272
>BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 101 bits (242), Expect = 6e-21
Identities = 67/261 (25%), Positives = 120/261 (45%), Gaps = 13/261 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y+ G +LG+G + + E D+++ AV P+ + + EI+L R L+H+
Sbjct: 62 YLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAK-PHQREKILNEIELHRDLQHR 120
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
+++ + ++ +Y+ +E C + + + + Y Q+L GL YLH
Sbjct: 121 HIVRFSH--HFEDADNIYIFLELCSRKSLAHIWKARHTLL-EPEVRYYLRQILSGLKYLH 177
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQ--EDICYTGQGSPAFQPPEIAN 271
+G++H+D+K GN +T + LK+ DFG+A L+ Q + IC G+P + PE+
Sbjct: 178 QRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTIC----GTPNYVAPEVL- 232
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXX 331
Q G + D+WS G +Y + G PFE ++ I +
Sbjct: 233 -LRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLL 291
Query: 332 XXHMLNRDPTLRPTVHEIRRH 352
+L P RP++ +I RH
Sbjct: 292 AA-ILRASPRDRPSIDQILRH 311
>AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 101 bits (242), Expect = 6e-21
Identities = 67/261 (25%), Positives = 120/261 (45%), Gaps = 13/261 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y+ G +LG+G + + E D+++ AV P+ + + EI+L R L+H+
Sbjct: 62 YLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAK-PHQREKILNEIELHRDLQHR 120
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
+++ + ++ +Y+ +E C + + + + Y Q+L GL YLH
Sbjct: 121 HIVRFSH--HFEDADNIYIFLELCSRKSLAHIWKARHTLL-EPEVRYYLRQILSGLKYLH 177
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQ--EDICYTGQGSPAFQPPEIAN 271
+G++H+D+K GN +T + LK+ DFG+A L+ Q + IC G+P + PE+
Sbjct: 178 QRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTIC----GTPNYVAPEVL- 232
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXX 331
Q G + D+WS G +Y + G PFE ++ I +
Sbjct: 233 -LRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLL 291
Query: 332 XXHMLNRDPTLRPTVHEIRRH 352
+L P RP++ +I RH
Sbjct: 292 AA-ILRASPRDRPSIDQILRH 311
>AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 101 bits (242), Expect = 6e-21
Identities = 67/261 (25%), Positives = 120/261 (45%), Gaps = 13/261 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y+ G +LG+G + + E D+++ AV P+ + + EI+L R L+H+
Sbjct: 62 YLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAK-PHQREKILNEIELHRDLQHR 120
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
+++ + ++ +Y+ +E C + + + + Y Q+L GL YLH
Sbjct: 121 HIVRFSH--HFEDADNIYIFLELCSRKSLAHIWKARHTLL-EPEVRYYLRQILSGLKYLH 177
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQ--EDICYTGQGSPAFQPPEIAN 271
+G++H+D+K GN +T + LK+ DFG+A L+ Q + IC G+P + PE+
Sbjct: 178 QRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTIC----GTPNYVAPEVL- 232
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXX 331
Q G + D+WS G +Y + G PFE ++ I +
Sbjct: 233 -LRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLL 291
Query: 332 XXHMLNRDPTLRPTVHEIRRH 352
+L P RP++ +I RH
Sbjct: 292 AA-ILRASPRDRPSIDQILRH 311
>AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 variant
protein.
Length = 621
Score = 101 bits (242), Expect = 6e-21
Identities = 67/261 (25%), Positives = 120/261 (45%), Gaps = 13/261 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y+ G +LG+G + + E D+++ AV P+ + + EI+L R L+H+
Sbjct: 37 YLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAK-PHQREKILNEIELHRDLQHR 95
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
+++ + ++ +Y+ +E C + + + + Y Q+L GL YLH
Sbjct: 96 HIVRFSH--HFEDADNIYIFLELCSRKSLAHIWKARHTLL-EPEVRYYLRQILSGLKYLH 152
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQ--EDICYTGQGSPAFQPPEIAN 271
+G++H+D+K GN +T + LK+ DFG+A L+ Q + IC G+P + PE+
Sbjct: 153 QRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTIC----GTPNYVAPEVL- 207
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXX 331
Q G + D+WS G +Y + G PFE ++ I +
Sbjct: 208 -LRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLL 266
Query: 332 XXHMLNRDPTLRPTVHEIRRH 352
+L P RP++ +I RH
Sbjct: 267 AA-ILRASPRDRPSIDQILRH 286
>AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein
kinase 3 protein.
Length = 489
Score = 101 bits (242), Expect = 6e-21
Identities = 67/253 (26%), Positives = 119/253 (47%), Gaps = 10/253 (3%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y++ ++GEG +G+ +L + N QN ++E LL ++H
Sbjct: 4 YMVLRMIGEGFFGRA--LLVQHESSNQMFAMKEIRLPKSFSN-TQNSRKEAVLLAKMKHP 60
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
N++ + + + +Y+VME+C G L ++ GK FP+ ++F Q+ G++++
Sbjct: 61 NIVAFKESF--EAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHI 118
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANG 272
H + V+H+DIK N+ LT + +K+ DFG A L + T G+P + PPEI
Sbjct: 119 HKKRVLHRDIKSKNIFLTQNGKVKLGDFGSARLLS--NPMAFACTYVGTPYYVPPEIWEN 176
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXXX 332
K DIWS G LY + T ++PF+ ++ L+ + +
Sbjct: 177 LPY--NNKSDIWSLGCILYELCTLKHPFQANSWKNLILKVCQGCISPLPSHYSYELQFLV 234
Query: 333 XHMLNRDPTLRPT 345
M R+P+ RP+
Sbjct: 235 KQMFKRNPSHRPS 247
>AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine
protein kinase protein.
Length = 646
Score = 101 bits (241), Expect = 7e-21
Identities = 67/261 (25%), Positives = 120/261 (45%), Gaps = 13/261 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y+ G +LG+G + + E D+++ AV P+ + + EI+L R L+H+
Sbjct: 62 YLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVVK-PHQREKILNEIELHRDLQHR 120
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
+++ + ++ +Y+ +E C + + + + Y Q+L GL YLH
Sbjct: 121 HIVRFSH--HFEDADNIYIFLELCSRKSLAHIWKARHTLL-EPEVRYYLRQILSGLKYLH 177
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQ--EDICYTGQGSPAFQPPEIAN 271
+G++H+D+K GN +T + LK+ DFG+A L+ Q + IC G+P + PE+
Sbjct: 178 QRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTIC----GTPNYVAPEVL- 232
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXX 331
Q G + D+WS G +Y + G PFE ++ I +
Sbjct: 233 -LRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLL 291
Query: 332 XXHMLNRDPTLRPTVHEIRRH 352
+L P RP++ +I RH
Sbjct: 292 AA-ILRASPRDRPSIDQILRH 311
>L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine
kinase protein.
Length = 841
Score = 100 bits (240), Expect = 1e-20
Identities = 66/259 (25%), Positives = 120/259 (46%), Gaps = 8/259 (3%)
Query: 99 VLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIEL 158
V+G+GSYG+V + + + + + ++E QLL L+H N++
Sbjct: 11 VVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRER--RAAEQEAQLLSQLKHPNIVTY 68
Query: 159 VDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGV 217
+ + +Y+VM FC G L L+ G+ P+ Q ++F+Q+ L YLH + +
Sbjct: 69 KES-WEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLHEKHI 127
Query: 218 VHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAEQFS 277
+H+D+K N+ LT +K+ D G+A L+ + D+ T G+P + PE+ +
Sbjct: 128 LHRDLKTQNVFLTRTNIIKVGDLGIARVLE--NHCDMASTLIGTPYYMSPELFSNKPY-- 183
Query: 278 GTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXXXXHMLN 337
K D+W+ G +Y M T ++ F ++ L+ I ML+
Sbjct: 184 NYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPAMPRDYSPELAELIRTMLS 243
Query: 338 RDPTLRPTVHEIRRHAWVQ 356
+ P RP+V I R +++
Sbjct: 244 KRPEERPSVRSILRQPYIK 262
>BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein.
Length = 781
Score = 100 bits (240), Expect = 1e-20
Identities = 66/259 (25%), Positives = 120/259 (46%), Gaps = 8/259 (3%)
Query: 99 VLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIEL 158
V+G+GSYG+V + + + + + ++E QLL L+H N++
Sbjct: 11 VVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRER--RAAEQEAQLLSQLKHPNIVTY 68
Query: 159 VDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGV 217
+ + +Y+VM FC G L L+ G+ P+ Q ++F+Q+ L YLH + +
Sbjct: 69 KES-WEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLHEKHI 127
Query: 218 VHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAEQFS 277
+H+D+K N+ LT +K+ D G+A L+ + D+ T G+P + PE+ +
Sbjct: 128 LHRDLKTQNVFLTRTNIIKVGDLGIARVLE--NHCDMASTLIGTPYYMSPELFSNKPY-- 183
Query: 278 GTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXXXXHMLN 337
K D+W+ G +Y M T ++ F ++ L+ I ML+
Sbjct: 184 NYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPAMPRDYSPELAELIRTMLS 243
Query: 338 RDPTLRPTVHEIRRHAWVQ 356
+ P RP+V I R +++
Sbjct: 244 KRPEERPSVRSILRQPYIK 262
>AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein.
Length = 343
Score = 100 bits (240), Expect = 1e-20
Identities = 74/269 (27%), Positives = 123/269 (45%), Gaps = 16/269 (5%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG-EQNVQREIQLLRI 149
+ + +G LG+G +G V + +S V G E ++REI++
Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKS--HFIVALKVLFKSQIEKEGVEHQLRREIEIQAH 131
Query: 150 LRHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQAHDYFLQLLDG 208
L H N++ L + Y +++++YL++E+ G L L+ S F +++ +L D
Sbjct: 132 LHHPNILRLYNYFY--DRRRIYLILEYAPRGELYKELQKSC--TFDEQRTATIMEELADA 187
Query: 209 LDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPE 268
L Y HG+ V+H+DIKP NLLL L LKI DFG + ++ +C G+ + PPE
Sbjct: 188 LMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHATSLRRKTMC----GTLDYLPPE 243
Query: 269 IANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXX 328
+ G + KVD+W GV Y + G PFE + I +
Sbjct: 244 MIEG--RIDNEKVDLWCIGVLCYELLVGN-PFESASHNETYRRIVK-VDLKFPASVPTGA 299
Query: 329 XXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +P+ R + ++ H WV+A
Sbjct: 300 QDLISKLLRHNPSERLPLAQVSAHPWVRA 328
>X66363-1|CAA47006.1| 496|Homo sapiens serine/threonine protein
kinase protein.
Length = 496
Score = 99 bits (238), Expect = 2e-20
Identities = 69/222 (31%), Positives = 107/222 (48%), Gaps = 11/222 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y+ D LGEG+Y V + +S + RE+ LL+ L+H
Sbjct: 165 YIKLDKLGEGTYATVYK---GKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHA 221
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
N++ L D+I+ ++ + LV E+ L+ L+ G + QLL GL Y H
Sbjct: 222 NIVTLHDIIHTEKS--LTLVFEYLDKDLKQYLDDC-GNIINMHNVKLFLFQLLRGLAYCH 278
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANG 272
Q V+H+D+KP NLL+ LK+ DFG+A A + ++ Y+ + ++PP+I G
Sbjct: 279 RQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTK---TYSNEVVTLWYRPPDILLG 335
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
+ +S T++D+W G Y M TGR F G V L I R
Sbjct: 336 STDYS-TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFR 376
>BT007299-1|AAP35963.1| 472|Homo sapiens PCTAIRE-motif protein
kinase 3 protein.
Length = 472
Score = 99 bits (238), Expect = 2e-20
Identities = 68/222 (30%), Positives = 106/222 (47%), Gaps = 11/222 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
YV D LGEG+Y V +S + RE+ LL+ L+H
Sbjct: 142 YVKLDKLGEGTYATV---FKGRSKLMENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHA 198
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
N++ L D+I+ D + + LV E+ L+ L+ G + QLL GL Y H
Sbjct: 199 NIVTLHDLIHTD--RSLTLVFEYLDSDLKQYLDHC-GNLMSMHNVKIFMFQLLRGLAYCH 255
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANG 272
+ ++H+D+KP NLL+ LK+ DFG+A A + ++ Y+ + ++PP++ G
Sbjct: 256 HRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTK---TYSNEVVTLWYRPPDVLLG 312
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
+ ++S T +D+W G Y M TGR F G V L I R
Sbjct: 313 STEYS-TPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFR 353
>BT006827-1|AAP35473.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 99 bits (238), Expect = 2e-20
Identities = 69/222 (31%), Positives = 107/222 (48%), Gaps = 11/222 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y+ D LGEG+Y V + +S + RE+ LL+ L+H
Sbjct: 165 YIKLDKLGEGTYATVYK---GKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHA 221
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
N++ L D+I+ ++ + LV E+ L+ L+ G + QLL GL Y H
Sbjct: 222 NIVTLHDIIHTEKS--LTLVFEYLDKDLKQYLDDC-GNIINMHNVKLFLFQLLRGLAYCH 278
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANG 272
Q V+H+D+KP NLL+ LK+ DFG+A A + ++ Y+ + ++PP+I G
Sbjct: 279 RQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTK---TYSNEVVTLWYRPPDILLG 335
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
+ +S T++D+W G Y M TGR F G V L I R
Sbjct: 336 STDYS-TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFR 376
>BC015607-1|AAH15607.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 99 bits (238), Expect = 2e-20
Identities = 69/222 (31%), Positives = 107/222 (48%), Gaps = 11/222 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y+ D LGEG+Y V + +S + RE+ LL+ L+H
Sbjct: 165 YIKLDKLGEGTYATVYK---GKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHA 221
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
N++ L D+I+ ++ + LV E+ L+ L+ G + QLL GL Y H
Sbjct: 222 NIVTLHDIIHTEKS--LTLVFEYLDKDLKQYLDDC-GNIINMHNVKLFLFQLLRGLAYCH 278
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANG 272
Q V+H+D+KP NLL+ LK+ DFG+A A + ++ Y+ + ++PP+I G
Sbjct: 279 RQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTK---TYSNEVVTLWYRPPDILLG 335
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
+ +S T++D+W G Y M TGR F G V L I R
Sbjct: 336 STDYS-TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFR 376
>BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for
IMAGE:3913546) protein.
Length = 451
Score = 99 bits (238), Expect = 2e-20
Identities = 66/259 (25%), Positives = 120/259 (46%), Gaps = 8/259 (3%)
Query: 99 VLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHKNVIEL 158
V+G+GSYG+V + + + + + ++E QLL L+H N++
Sbjct: 11 VVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRER--RAAEQEAQLLSQLKHPNIVTY 68
Query: 159 VDVIYNDEKQKMYLVMEFCVGV-LQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGV 217
+ + +Y+VM FC G L L+ G+ P+ Q ++F+Q+ L YLH + +
Sbjct: 69 KES-WEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLHEKHI 127
Query: 218 VHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAEQFS 277
+H+D+K N+ LT +K+ D G+A L+ + D+ T G+P + PE+ +
Sbjct: 128 LHRDLKTQNVFLTRTNIIKVGDLGIARVLE--NHCDMASTLIGTPYYMSPELFSNKPY-- 183
Query: 278 GTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXXXXHMLN 337
K D+W+ G +Y M T ++ F ++ L+ I ML+
Sbjct: 184 NYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRTMLS 243
Query: 338 RDPTLRPTVHEIRRHAWVQ 356
+ P RP+V I R +++
Sbjct: 244 KRPEERPSVRSILRQPYIK 262
>BC011526-1|AAH11526.1| 472|Homo sapiens PCTAIRE protein kinase 3
protein.
Length = 472
Score = 99 bits (238), Expect = 2e-20
Identities = 68/222 (30%), Positives = 106/222 (47%), Gaps = 11/222 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
YV D LGEG+Y V +S + RE+ LL+ L+H
Sbjct: 142 YVKLDKLGEGTYATV---FKGRSKLMENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHA 198
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
N++ L D+I+ D + + LV E+ L+ L+ G + QLL GL Y H
Sbjct: 199 NIVTLHDLIHTD--RSLTLVFEYLDSDLKQYLDHC-GNLMSMHNVKIFMFQLLRGLAYCH 255
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANG 272
+ ++H+D+KP NLL+ LK+ DFG+A A + ++ Y+ + ++PP++ G
Sbjct: 256 HRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTK---TYSNEVVTLWYRPPDVLLG 312
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
+ ++S T +D+W G Y M TGR F G V L I R
Sbjct: 313 STEYS-TPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFR 353
>BC009852-1|AAH09852.2| 395|Homo sapiens PCTK1 protein protein.
Length = 395
Score = 99 bits (238), Expect = 2e-20
Identities = 69/222 (31%), Positives = 107/222 (48%), Gaps = 11/222 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y+ D LGEG+Y V + +S + RE+ LL+ L+H
Sbjct: 64 YIKLDKLGEGTYATVYK---GKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHA 120
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
N++ L D+I+ ++ + LV E+ L+ L+ G + QLL GL Y H
Sbjct: 121 NIVTLHDIIHTEKS--LTLVFEYLDKDLKQYLDDC-GNIINMHNVKLFLFQLLRGLAYCH 177
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANG 272
Q V+H+D+KP NLL+ LK+ DFG+A A + ++ Y+ + ++PP+I G
Sbjct: 178 RQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTK---TYSNEVVTLWYRPPDILLG 234
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
+ +S T++D+W G Y M TGR F G V L I R
Sbjct: 235 STDYS-TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFR 275
>BC006190-1|AAH06190.1| 448|Homo sapiens PCTK1 protein protein.
Length = 448
Score = 99 bits (238), Expect = 2e-20
Identities = 69/222 (31%), Positives = 107/222 (48%), Gaps = 11/222 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y+ D LGEG+Y V + +S + RE+ LL+ L+H
Sbjct: 117 YIKLDKLGEGTYATVYK---GKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHA 173
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
N++ L D+I+ ++ + LV E+ L+ L+ G + QLL GL Y H
Sbjct: 174 NIVTLHDIIHTEKS--LTLVFEYLDKDLKQYLDDC-GNIINMHNVKLFLFQLLRGLAYCH 230
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANG 272
Q V+H+D+KP NLL+ LK+ DFG+A A + ++ Y+ + ++PP+I G
Sbjct: 231 RQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTK---TYSNEVVTLWYRPPDILLG 287
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
+ +S T++D+W G Y M TGR F G V L I R
Sbjct: 288 STDYS-TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFR 328
>BC001048-1|AAH01048.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 99 bits (238), Expect = 2e-20
Identities = 69/222 (31%), Positives = 107/222 (48%), Gaps = 11/222 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y+ D LGEG+Y V + +S + RE+ LL+ L+H
Sbjct: 165 YIKLDKLGEGTYATVYK---GKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHA 221
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
N++ L D+I+ ++ + LV E+ L+ L+ G + QLL GL Y H
Sbjct: 222 NIVTLHDIIHTEKS--LTLVFEYLDKDLKQYLDDC-GNIINMHNVKLFLFQLLRGLAYCH 278
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANG 272
Q V+H+D+KP NLL+ LK+ DFG+A A + ++ Y+ + ++PP+I G
Sbjct: 279 RQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTK---TYSNEVVTLWYRPPDILLG 335
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
+ +S T++D+W G Y M TGR F G V L I R
Sbjct: 336 STDYS-TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFR 376
>AY353238-1|AAR13066.1| 504|Homo sapiens PCTAIRE protein kinase 3
isoform b protein.
Length = 504
Score = 99 bits (238), Expect = 2e-20
Identities = 68/222 (30%), Positives = 106/222 (47%), Gaps = 11/222 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
YV D LGEG+Y V +S + RE+ LL+ L+H
Sbjct: 174 YVKLDKLGEGTYATV---FKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHA 230
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
N++ L D+I+ D + + LV E+ L+ L+ G + QLL GL Y H
Sbjct: 231 NIVTLHDLIHTD--RSLTLVFEYLDSDLKQYLDHC-GNLMSMHNVKIFMFQLLRGLAYCH 287
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANG 272
+ ++H+D+KP NLL+ LK+ DFG+A A + ++ Y+ + ++PP++ G
Sbjct: 288 HRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTK---TYSNEVVTLWYRPPDVLLG 344
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
+ ++S T +D+W G Y M TGR F G V L I R
Sbjct: 345 STEYS-TPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFR 385
>AY353237-1|AAR13065.1| 474|Homo sapiens PCTAIRE protein kinase 3
isoform a protein.
Length = 474
Score = 99 bits (238), Expect = 2e-20
Identities = 68/222 (30%), Positives = 106/222 (47%), Gaps = 11/222 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
YV D LGEG+Y V +S + RE+ LL+ L+H
Sbjct: 144 YVKLDKLGEGTYATV---FKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHA 200
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
N++ L D+I+ D + + LV E+ L+ L+ G + QLL GL Y H
Sbjct: 201 NIVTLHDLIHTD--RSLTLVFEYLDSDLKQYLDHC-GNLMSMHNVKIFMFQLLRGLAYCH 257
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANG 272
+ ++H+D+KP NLL+ LK+ DFG+A A + ++ Y+ + ++PP++ G
Sbjct: 258 HRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTK---TYSNEVVTLWYRPPDVLLG 314
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
+ ++S T +D+W G Y M TGR F G V L I R
Sbjct: 315 STEYS-TPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFR 355
>AL357131-4|CAH72012.1| 472|Homo sapiens PCTAIRE protein kinase 3
protein.
Length = 472
Score = 99 bits (238), Expect = 2e-20
Identities = 68/222 (30%), Positives = 106/222 (47%), Gaps = 11/222 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
YV D LGEG+Y V +S + RE+ LL+ L+H
Sbjct: 142 YVKLDKLGEGTYATV---FKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHA 198
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
N++ L D+I+ D + + LV E+ L+ L+ G + QLL GL Y H
Sbjct: 199 NIVTLHDLIHTD--RSLTLVFEYLDSDLKQYLDHC-GNLMSMHNVKIFMFQLLRGLAYCH 255
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANG 272
+ ++H+D+KP NLL+ LK+ DFG+A A + ++ Y+ + ++PP++ G
Sbjct: 256 HRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTK---TYSNEVVTLWYRPPDVLLG 312
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
+ ++S T +D+W G Y M TGR F G V L I R
Sbjct: 313 STEYS-TPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFR 353
>AL096791-1|CAD20055.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 99 bits (238), Expect = 2e-20
Identities = 69/222 (31%), Positives = 107/222 (48%), Gaps = 11/222 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y+ D LGEG+Y V + +S + RE+ LL+ L+H
Sbjct: 165 YIKLDKLGEGTYATVYK---GKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHA 221
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
N++ L D+I+ ++ + LV E+ L+ L+ G + QLL GL Y H
Sbjct: 222 NIVTLHDIIHTEKS--LTLVFEYLDKDLKQYLDDC-GNIINMHNVKLFLFQLLRGLAYCH 278
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANG 272
Q V+H+D+KP NLL+ LK+ DFG+A A + ++ Y+ + ++PP+I G
Sbjct: 279 RQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTK---TYSNEVVTLWYRPPDILLG 335
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
+ +S T++D+W G Y M TGR F G V L I R
Sbjct: 336 STDYS-TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFR 376
>AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase
protein.
Length = 347
Score = 99 bits (238), Expect = 2e-20
Identities = 76/271 (28%), Positives = 123/271 (45%), Gaps = 16/271 (5%)
Query: 91 VGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNG-EQNVQREIQLLRI 149
+ + +G LG+G +G V + +S V G E ++REI++
Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKS--HFIVALKVLFKSQIEKEGVEHQLRREIEIQAH 131
Query: 150 LRHKNVIELVDVIYNDEKQKMYLVMEFCV-GVLQDMLESSPGKKFPQRQA--HDYFLQLL 206
L H N++ L + Y +++++YL++E+ G+L L+ S QR A +L
Sbjct: 132 LHHPNILRLYNYFY--DRRRIYLILEYAPRGMLYKELQKSCTFD-EQRTATVRAVMEELA 188
Query: 207 DGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQP 266
D L Y HG+ V+H+DIKP NLLL L LKI DFG + ++ +C G+ + P
Sbjct: 189 DALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMC----GTLDYLP 244
Query: 267 PEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXX 326
PE+ G + KVD+W GV Y + G PFE + I +
Sbjct: 245 PEMIEG--RMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVK-VDLKFPASVPT 301
Query: 327 XXXXXXXHMLNRDPTLRPTVHEIRRHAWVQA 357
+L +P+ R + ++ H WV+A
Sbjct: 302 GAQDLISKLLRHNPSERLPLAQVSAHPWVRA 332
>AB209307-1|BAD92544.1| 436|Homo sapiens PCTAIRE protein kinase 3
isoform b variant protein.
Length = 436
Score = 99 bits (238), Expect = 2e-20
Identities = 68/222 (30%), Positives = 106/222 (47%), Gaps = 11/222 (4%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
YV D LGEG+Y V +S + RE+ LL+ L+H
Sbjct: 106 YVKLDKLGEGTYATV---FKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHA 162
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLH 213
N++ L D+I+ D + + LV E+ L+ L+ G + QLL GL Y H
Sbjct: 163 NIVTLHDLIHTD--RSLTLVFEYLDSDLKQYLDHC-GNLMSMHNVKIFMFQLLRGLAYCH 219
Query: 214 GQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPA-FQPPEIANG 272
+ ++H+D+KP NLL+ LK+ DFG+A A + ++ Y+ + ++PP++ G
Sbjct: 220 HRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTK---TYSNEVVTLWYRPPDVLLG 276
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISR 314
+ ++S T +D+W G Y M TGR F G V L I R
Sbjct: 277 STEYS-TPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFR 317
>X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein
kinase protein.
Length = 603
Score = 99.1 bits (236), Expect = 3e-20
Identities = 70/258 (27%), Positives = 119/258 (46%), Gaps = 11/258 (4%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
+YV G LG+G + K E+ D+ + P+ + + EI + R L H
Sbjct: 52 RYVRGRFLGKGGFAKCFEISDADTK-EVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAH 110
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKK-FPQRQAHDYFLQLLDGLDY 211
++V+ + ++ +++V+E C + +LE +K + +A Y Q++ G Y
Sbjct: 111 QHVVGFHG--FFEDNDFVFVVLELCRR--RSLLEPHKRRKALTEPEARYYLRQIVLGCQY 166
Query: 212 LHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIAN 271
LH V+H+D+K GNL L D +KI DFG+A ++ + T G+P + PE+ +
Sbjct: 167 LHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERK--KTLCGTPNYIAPEVLS 224
Query: 272 GAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXXX 331
E +VD+WS G +Y + G+ PFE + I +
Sbjct: 225 KKEH--SFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKK-NEYSIPKHINPVAASL 281
Query: 332 XXHMLNRDPTLRPTVHEI 349
ML DPT RPT++E+
Sbjct: 282 IQKMLQTDPTARPTINEL 299
>U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinase
protein.
Length = 493
Score = 99.1 bits (236), Expect = 3e-20
Identities = 63/212 (29%), Positives = 106/212 (50%), Gaps = 8/212 (3%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
KY ++GEGSYG V + + + R V ++ REI+LL+ LRH
Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDT--GRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
+N++ L++V +K++ YLV EF + D LE P + Y Q+++G+ +
Sbjct: 61 ENLVNLLEVC--KKKKRWYLVFEFVDHTILDDLELFPNG-LDYQVVQKYLFQIINGIGFC 117
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANG 272
H ++H+DIKP N+L++ +K+ DFG A L + Y + ++ PE+ G
Sbjct: 118 HSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYV--ATRWYRAPELLVG 175
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDN 304
++ G VD+W+ G + M G F GD+
Sbjct: 176 DVKY-GKAVDVWAIGCLVTEMFMGEPLFPGDS 206
>CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein.
Length = 358
Score = 99.1 bits (236), Expect = 3e-20
Identities = 75/271 (27%), Positives = 122/271 (45%), Gaps = 9/271 (3%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y++G LG+GSY KVK S+ L E+ + RE+ +L + H
Sbjct: 12 YIVGINLGKGSYAKVKSAY-SERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHG 70
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGK-KFPQRQAHDYFLQLLDGLDYL 212
++I+ + I+ ++Y++ME +GV D+LE + + A F QL + Y
Sbjct: 71 SIIKTYE-IFETSDGRIYIIME--LGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYC 127
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEAL--DMFSQEDICYTGQGSPAFQPPEIA 270
H +VH+D+K NLLL D +K++DFG ++ D + + T GS A+ PE+
Sbjct: 128 HDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVL 187
Query: 271 NGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXX 330
+ DIWS GV LY M G P++ ++ ++L
Sbjct: 188 QSI-PYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECK 246
Query: 331 XXXH-MLNRDPTLRPTVHEIRRHAWVQATPP 360
+ ML D + R + EI H+W+Q P
Sbjct: 247 DLIYRMLQPDVSQRLHIDEILSHSWLQPPKP 277
>BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent
kinase-like 2 (CDC2-related kinase) protein.
Length = 493
Score = 99.1 bits (236), Expect = 3e-20
Identities = 63/212 (29%), Positives = 106/212 (50%), Gaps = 8/212 (3%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
KY ++GEGSYG V + + + R V ++ REI+LL+ LRH
Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDT--GRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
+N++ L++V +K++ YLV EF + D LE P + Y Q+++G+ +
Sbjct: 61 ENLVNLLEVC--KKKKRWYLVFEFVDHTILDDLELFPNG-LDYQVVQKYLFQIINGIGFC 117
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANG 272
H ++H+DIKP N+L++ +K+ DFG A L + Y + ++ PE+ G
Sbjct: 118 HSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYV--ATRWYRAPELLVG 175
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDN 304
++ G VD+W+ G + M G F GD+
Sbjct: 176 DVKY-GKAVDVWAIGCLVTEMFMGEPLFPGDS 206
>BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent
kinase-like 2 (CDC2-related kinase) protein.
Length = 493
Score = 99.1 bits (236), Expect = 3e-20
Identities = 63/212 (29%), Positives = 106/212 (50%), Gaps = 8/212 (3%)
Query: 93 KYVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRH 152
KY ++GEGSYG V + + + R V ++ REI+LL+ LRH
Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDT--GRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60
Query: 153 KNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYL 212
+N++ L++V +K++ YLV EF + D LE P + Y Q+++G+ +
Sbjct: 61 ENLVNLLEVC--KKKKRWYLVFEFVDHTILDDLELFPNG-LDYQVVQKYLFQIINGIGFC 117
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANG 272
H ++H+DIKP N+L++ +K+ DFG A L + Y + ++ PE+ G
Sbjct: 118 HSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYV--ATRWYRAPELLVG 175
Query: 273 AEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDN 304
++ G VD+W+ G + M G F GD+
Sbjct: 176 DVKY-GKAVDVWAIGCLVTEMFMGEPLFPGDS 206
>BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 99.1 bits (236), Expect = 3e-20
Identities = 75/271 (27%), Positives = 122/271 (45%), Gaps = 9/271 (3%)
Query: 94 YVMGDVLGEGSYGKVKEMLDSQSLCRRAVXXXXXXXXXXXPNGEQNVQREIQLLRILRHK 153
Y++G LG+GSY KVK S+ L E+ + RE+ +L + H
Sbjct: 12 YIVGINLGKGSYAKVKSAY-SERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHG 70
Query: 154 NVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGK-KFPQRQAHDYFLQLLDGLDYL 212
++I+ + I+ ++Y++ME +GV D+LE + + A F QL + Y
Sbjct: 71 SIIKTYE-IFETSDGRIYIIME--LGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYC 127
Query: 213 HGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEAL--DMFSQEDICYTGQGSPAFQPPEIA 270
H +VH+D+K NLLL D +K++DFG ++ D + + T GS A+ PE+
Sbjct: 128 HDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVL 187
Query: 271 NGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRXXXXXXXXXXXXXXXX 330
+ DIWS GV LY M G P++ ++ ++L
Sbjct: 188 QSI-PYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECK 246
Query: 331 XXXH-MLNRDPTLRPTVHEIRRHAWVQATPP 360
+ ML D + R + EI H+W+Q P
Sbjct: 247 DLIYRMLQPDVSQRLHIDEILSHSWLQPPKP 277
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.136 0.406
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 68,203,674
Number of Sequences: 224733
Number of extensions: 2669887
Number of successful extensions: 11323
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 2386
Number of HSP's successfully gapped in prelim test: 361
Number of HSP's that attempted gapping in prelim test: 4926
Number of HSP's gapped (non-prelim): 3264
length of query: 484
length of database: 73,234,838
effective HSP length: 93
effective length of query: 391
effective length of database: 52,334,669
effective search space: 20462855579
effective search space used: 20462855579
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 67 (31.1 bits)
- SilkBase 1999-2023 -