Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000415-TA|BGIBMGA000415-PA|IPR009091|Regulator of
chromosome condensation/beta-lactamase-inhibitor protein II,
IPR000408|Regulator of chromosome condensation, RCC1
(993 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC029052-1|AAH29052.1| 551|Homo sapiens regulator of chromosome... 107 3e-22
AY341245-1|AAP88928.1| 551|Homo sapiens chromosome condensation... 107 3e-22
AL157813-1|CAH70795.1| 551|Homo sapiens regulator of chromosome... 107 3e-22
AF060219-1|AAC79987.1| 551|Homo sapiens RCC1-like G exchanging ... 107 3e-22
AB209543-1|BAD92780.1| 556|Homo sapiens RCC1-like G exchanging ... 107 3e-22
AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protei... 106 4e-22
AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligas... 105 6e-22
U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein. 104 1e-21
D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein. 104 2e-21
BC038960-1|AAH38960.1| 368|Homo sapiens HERC3 protein protein. 103 2e-21
AC098582-1|AAY41038.1| 382|Homo sapiens unknown protein. 103 2e-21
BC038104-1|AAH38104.1| 355|Homo sapiens RCBTB1 protein protein. 102 6e-21
AL139321-5|CAH71047.1| 531|Homo sapiens regulator of chromosome... 101 1e-20
AK096654-1|BAC04833.1| 531|Homo sapiens protein ( Homo sapiens ... 101 1e-20
AJ319660-1|CAC40027.1| 531|Homo sapiens guanine nucleotide exch... 101 1e-20
AF334406-1|AAK38372.1| 531|Homo sapiens CLLL7 protein protein. 101 1e-20
BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4 p... 101 1e-20
AY650033-1|AAV66579.1| 979|Homo sapiens HECT and RCC1 containin... 101 1e-20
AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containin... 101 1e-20
AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4 p... 101 1e-20
AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4 p... 101 1e-20
AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein. 101 1e-20
X97668-1|CAA66258.1| 815|Homo sapiens XLRP3 protein. 98 1e-19
U57629-1|AAC50481.1| 815|Homo sapiens retinitis pigmentosa GTPa... 98 1e-19
BC031624-1|AAH31624.1| 480|Homo sapiens RPGR protein protein. 98 1e-19
AL606748-2|CAI95407.1| 815|Homo sapiens retinitis pigmentosa GT... 98 1e-19
AK223491-1|BAD97211.1| 815|Homo sapiens retinitis pigmentosa GT... 98 1e-19
AJ238395-1|CAB54002.1| 646|Homo sapiens RPGR protein protein. 98 1e-19
AJ318463-1|CAC86116.1| 815|Homo sapiens retinitis pigmentosa GT... 97 2e-19
AF225407-1|AAO27483.1| 409|Homo sapiens HERC2 protein. 97 2e-19
BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6 p... 93 4e-18
AY653203-1|AAV66897.1| 322|Homo sapiens truncated HERC6 protein. 93 4e-18
AY653202-1|AAV66896.1| 364|Homo sapiens truncated HERC6 protein. 93 4e-18
AY653201-1|AAV66895.1| 986|Homo sapiens HERC6 splice variant pr... 93 4e-18
AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein. 93 4e-18
AB046813-1|BAB13419.1| 953|Homo sapiens KIAA1593 protein protein. 93 4e-18
BC065375-1|AAH65375.1| 458|Homo sapiens secretion regulating gu... 92 8e-18
AJ243951-1|CAB60833.1| 288|Homo sapiens deafness locus associat... 92 8e-18
AJ243950-1|CAB60832.1| 458|Homo sapiens deafness locus associat... 92 8e-18
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 88 2e-16
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 88 2e-16
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 88 2e-16
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 88 2e-16
AF224249-1|AAO27475.1| 328|Homo sapiens HERC2 protein. 79 8e-14
AL356741-1|CAH74146.1| 907|Homo sapiens hect domain and RLD 4 p... 78 2e-13
AL133551-1|CAI16031.1| 907|Homo sapiens hect domain and RLD 4 p... 78 2e-13
BC053908-1|AAH53908.1| 522|Homo sapiens RCC2 protein protein. 77 3e-13
BC042141-1|AAH42141.1| 522|Homo sapiens regulator of chromosome... 77 3e-13
AJ421269-1|CAD13148.1| 522|Homo sapiens RCC1-like protein protein. 77 3e-13
AB040903-1|BAA95994.1| 564|Homo sapiens KIAA1470 protein protein. 77 3e-13
BC019008-1|AAH19008.1| 464|Homo sapiens Williams-Beuren syndrom... 76 5e-13
BC007823-1|AAH07823.1| 464|Homo sapiens Williams-Beuren syndrom... 76 5e-13
AF410455-1|AAM62304.1| 464|Homo sapiens RCC1-like G exchanging ... 76 5e-13
AL359612-1|CAB94882.1| 333|Homo sapiens hypothetical protein pr... 75 1e-12
BC032712-1|AAH32712.1| 454|Homo sapiens WBSCR16 protein protein. 75 1e-12
X12654-1|CAA31182.1| 421|Homo sapiens protein ( Human mRNA for ... 70 4e-11
X06130-1|CAA29496.1| 421|Homo sapiens protein ( Human mRNA for ... 70 4e-11
D00591-1|BAA00469.1| 421|Homo sapiens RCC1 protein. 70 4e-11
CR407693-1|CAG28621.1| 421|Homo sapiens CHC1 protein. 70 4e-11
BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9 p... 70 4e-11
BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis ... 70 4e-11
BC069198-1|AAH69198.1| 452|Homo sapiens regulator of chromosome... 70 4e-11
BC036903-1|AAH36903.1| 421|Homo sapiens regulator of chromosome... 70 4e-11
BC010067-1|AAH10067.1| 421|Homo sapiens regulator of chromosome... 70 4e-11
BC007300-1|AAH07300.1| 421|Homo sapiens regulator of chromosome... 70 4e-11
AL513497-2|CAI22287.1| 421|Homo sapiens regulator of chromosome... 70 4e-11
AF498924-1|AAM21072.1| 421|Homo sapiens regulator of chromosome... 70 4e-11
AC007055-4|AAD31939.1| 414|Homo sapiens protein ( Homo sapiens ... 70 4e-11
AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERC... 70 5e-11
AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek... 70 5e-11
AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein. 70 5e-11
AK092403-1|BAC03879.1| 184|Homo sapiens protein ( Homo sapiens ... 69 8e-11
BC004933-1|AAH04933.1| 351|Homo sapiens RCC2 protein protein. 67 3e-10
BC040929-1|AAH40929.1| 651|Homo sapiens HERC1 protein protein. 62 1e-08
BC040695-1|AAH40695.1| 358|Homo sapiens WBSCR16 protein protein. 60 5e-08
AY650034-1|AAV66580.1| 110|Homo sapiens HECT and RCC1 containin... 58 2e-07
AY650032-1|AAV66578.1| 117|Homo sapiens HECT and RCC1 containin... 58 2e-07
AL359257-2|CAI39759.1| 4640|Homo sapiens AC001226.5 protein. 57 3e-07
AL159158-1|CAI16842.1| 4640|Homo sapiens AC001226.5 protein. 57 3e-07
AL159154-1|CAH73736.1| 4640|Homo sapiens AC001226.5 protein. 57 3e-07
AF075587-1|AAC39928.1| 4641|Homo sapiens protein associated with... 57 3e-07
AC004460-2|AAC06339.1| 371|Homo sapiens WUGSC:H_DJ1086D14.2 pro... 56 5e-07
BC029174-1|AAH29174.1| 812|Homo sapiens ALS2 protein protein. 55 1e-06
BC071576-1|AAH71576.1| 1237|Homo sapiens ALS2 protein protein. 54 3e-06
AK023024-1|BAB14362.1| 396|Homo sapiens protein ( Homo sapiens ... 54 3e-06
AF391100-1|AAL14103.1| 1657|Homo sapiens alsin protein. 54 3e-06
AC007279-1|AAY15058.1| 1598|Homo sapiens unknown protein. 54 3e-06
AB053306-1|BAB69015.1| 396|Homo sapiens ALS2 protein. 54 3e-06
AB053305-1|BAB69014.1| 1657|Homo sapiens ALS2 protein. 54 3e-06
AB046783-1|BAB13389.2| 1658|Homo sapiens KIAA1563 protein protein. 54 3e-06
DQ005634-1|AAY55907.1| 1196|Homo sapiens inhibitor of Bruton's t... 53 4e-06
DQ005633-1|AAY55906.1| 1353|Homo sapiens inhibitor of Bruton's t... 53 4e-06
BC113698-1|AAI13699.1| 1353|Homo sapiens inhibitor of Bruton aga... 53 4e-06
BC113696-1|AAI13697.1| 1353|Homo sapiens inhibitor of Bruton aga... 53 4e-06
AL050333-2|CAI23416.1| 1187|Homo sapiens RP1-93K22.1 protein. 53 4e-06
AB037838-1|BAA92655.2| 1379|Homo sapiens KIAA1417 protein protein. 53 4e-06
BC067293-1|AAH67293.1| 580|Homo sapiens F-box protein 24 protein. 50 4e-05
AC069281-1|AAP21863.1| 580|Homo sapiens unknown protein. 50 4e-05
AF225404-1|AAO27482.1| 259|Homo sapiens HERC2 protein. 48 1e-04
BC113826-1|AAI13827.1| 244|Homo sapiens RCCD1 protein protein. 47 4e-04
X54131-1|CAA38066.1| 1997|Homo sapiens protein-tyrosine phosphat... 36 0.95
BX648771-1|CAE46198.1| 1956|Homo sapiens hypothetical protein pr... 36 0.95
BC113463-1|AAI13464.1| 1997|Homo sapiens protein tyrosine phosph... 36 0.95
BC101679-1|AAI01680.1| 1997|Homo sapiens protein tyrosine phosph... 36 0.95
AK128562-1|BAC87502.1| 1407|Homo sapiens protein ( Homo sapiens ... 36 0.95
BC031555-1|AAH31555.1| 1024|Homo sapiens NLRC4 protein protein. 32 8.8
AY358152-1|AAQ88519.1| 1024|Homo sapiens CARD12 protein. 32 8.8
AY035391-1|AAK59843.1| 1024|Homo sapiens ICE-protease activating... 32 8.8
AY032589-1|AAK38730.1| 1024|Homo sapiens caspase recruitment dom... 32 8.8
AY027788-1|AAK14777.1| 359|Homo sapiens CLANB protein. 32 8.8
AY027787-1|AAK14776.1| 1024|Homo sapiens CLANA protein. 32 8.8
AL389934-1|CAB97523.1| 439|Homo sapiens hypothetical protein, w... 32 8.8
AF376061-1|AAK53443.1| 1024|Homo sapiens caspase recruitment dom... 32 8.8
>BC029052-1|AAH29052.1| 551|Homo sapiens regulator of chromosome
condensation (RCC1) and BTB (POZ) domain containing pro
protein.
Length = 551
Score = 107 bits (256), Expect = 3e-22
Identities = 71/222 (31%), Positives = 112/222 (50%), Gaps = 13/222 (5%)
Query: 320 TCGLAHWAVVSDGNARVMMASTPVNTELIGR-VIDVACGRHHTLILTENG-LYSAGDNTF 377
T G ++ + +G + ++T L + VI+VACG +H+L+LT +G +++ G N
Sbjct: 122 TWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNS 181
Query: 378 GQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGV 437
GQ+ L+ ++ +V +A G AV G + WG+
Sbjct: 182 GQVGSGSTVNQPIPRRVTG---CLQNKV-----VVTIACGQMCCMAVVDTGEVYVWGYNG 233
Query: 438 HGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQ 497
+GQLGLGN +Q TP V G +VQ V CG H+++LT G+++A GA+ +GQLGTG
Sbjct: 234 NGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGN 293
Query: 498 RGKASLPVRVALHEP--VRALAAGYFH-NLALTHKGEVYVWG 536
+ S P V + + + A H + A T G VY+WG
Sbjct: 294 KSNQSYPTPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMWG 335
Score = 96.3 bits (229), Expect = 5e-19
Identities = 64/236 (27%), Positives = 111/236 (47%), Gaps = 24/236 (10%)
Query: 402 RVRLAGGAPLVCVAAGHY-HSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTKFL 459
R+ G + C++ G H G + TWG + QLG G + P + T
Sbjct: 91 RLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLS 150
Query: 460 GRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVA---LHEPVRAL 516
++V V CG+ HS++LT GE++A G + GQ+G+G +P RV ++ V +
Sbjct: 151 NKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTI 210
Query: 517 AAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTT 576
A G +A+ GEVYVWG + + L + ++ P+
Sbjct: 211 ACGQMCCMAVVDTGEVYVWGYN---------------GNGQLGLGNSGNQ---PTPCRVA 252
Query: 577 NVRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTE 631
++G R+ +++ G+ H+ ++ + G +Y WG N GQLG+G++ PT V + +
Sbjct: 253 ALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKD 308
Score = 93.1 bits (221), Expect = 4e-18
Identities = 59/185 (31%), Positives = 86/185 (46%), Gaps = 11/185 (5%)
Query: 357 GRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAA 416
G H L TE +++ G N + QL +V + VA
Sbjct: 108 GPHIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQV--------IEVAC 159
Query: 417 GHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQ-SVGCGACHSVL 475
G YHS + + G + WG+ GQ+G G+ +Q P+ VT L KV ++ CG +
Sbjct: 160 GSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMA 219
Query: 476 LTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPVRA--LAAGYFHNLALTHKGEVY 533
+ GE++ G + GQLG G G P RVA + +R +A GY H L LT +G+VY
Sbjct: 220 VVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVY 279
Query: 534 VWGAS 538
WGA+
Sbjct: 280 AWGAN 284
Score = 69.7 bits (163), Expect = 5e-11
Identities = 54/193 (27%), Positives = 83/193 (43%), Gaps = 22/193 (11%)
Query: 439 GQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA-CHSVLLTRGGELWACGASVFGQLGTGQ 497
G LGLG++ P+ + G+K+ + G+ H VL T GE++ G + + QLG G
Sbjct: 76 GCLGLGDVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNGT 135
Query: 498 RGKASLPVRVAL---HEPVRALAAGYFHNLALTHKGEVYVWGASPQ-QVXXXXXXXXXEP 553
+P ++ ++ V +A G +H+L LT GEV+ WG + QV P
Sbjct: 136 TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP 195
Query: 554 SSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLG 613
T C+ V V I+ G + + G +Y WG N +GQLG
Sbjct: 196 RRVT-------------GCLQNKVV----VTIACGQMCCMAVVDTGEVYVWGYNGNGQLG 238
Query: 614 SGDRKQIQIPTEV 626
G+ P V
Sbjct: 239 LGNSGNQPTPCRV 251
>AY341245-1|AAP88928.1| 551|Homo sapiens chromosome condensation
1-like protein.
Length = 551
Score = 107 bits (256), Expect = 3e-22
Identities = 71/222 (31%), Positives = 112/222 (50%), Gaps = 13/222 (5%)
Query: 320 TCGLAHWAVVSDGNARVMMASTPVNTELIGR-VIDVACGRHHTLILTENG-LYSAGDNTF 377
T G ++ + +G + ++T L + VI+VACG +H+L+LT +G +++ G N
Sbjct: 122 TWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNS 181
Query: 378 GQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGV 437
GQ+ L+ ++ +V +A G AV G + WG+
Sbjct: 182 GQVGSGSTVNQPIPRRVTG---CLQNKV-----VVTIACGQMCCMAVVDTGEVYVWGYNG 233
Query: 438 HGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQ 497
+GQLGLGN +Q TP V G +VQ V CG H+++LT G+++A GA+ +GQLGTG
Sbjct: 234 NGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGN 293
Query: 498 RGKASLPVRVALHEP--VRALAAGYFH-NLALTHKGEVYVWG 536
+ S P V + + + A H + A T G VY+WG
Sbjct: 294 KSNQSYPTPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMWG 335
Score = 96.3 bits (229), Expect = 5e-19
Identities = 64/236 (27%), Positives = 111/236 (47%), Gaps = 24/236 (10%)
Query: 402 RVRLAGGAPLVCVAAGHY-HSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTKFL 459
R+ G + C++ G H G + TWG + QLG G + P + T
Sbjct: 91 RLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLS 150
Query: 460 GRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVA---LHEPVRAL 516
++V V CG+ HS++LT GE++A G + GQ+G+G +P RV ++ V +
Sbjct: 151 NKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTI 210
Query: 517 AAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTT 576
A G +A+ GEVYVWG + + L + ++ P+
Sbjct: 211 ACGQMCCMAVVDTGEVYVWGYN---------------GNGQLGLGNSGNQ---PTPCRVA 252
Query: 577 NVRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTE 631
++G R+ +++ G+ H+ ++ + G +Y WG N GQLG+G++ PT V + +
Sbjct: 253 ALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKD 308
Score = 93.1 bits (221), Expect = 4e-18
Identities = 59/185 (31%), Positives = 86/185 (46%), Gaps = 11/185 (5%)
Query: 357 GRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAA 416
G H L TE +++ G N + QL +V + VA
Sbjct: 108 GPHIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQV--------IEVAC 159
Query: 417 GHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQ-SVGCGACHSVL 475
G YHS + + G + WG+ GQ+G G+ +Q P+ VT L KV ++ CG +
Sbjct: 160 GSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMA 219
Query: 476 LTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPVRA--LAAGYFHNLALTHKGEVY 533
+ GE++ G + GQLG G G P RVA + +R +A GY H L LT +G+VY
Sbjct: 220 VVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVY 279
Query: 534 VWGAS 538
WGA+
Sbjct: 280 AWGAN 284
Score = 69.7 bits (163), Expect = 5e-11
Identities = 54/193 (27%), Positives = 83/193 (43%), Gaps = 22/193 (11%)
Query: 439 GQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA-CHSVLLTRGGELWACGASVFGQLGTGQ 497
G LGLG++ P+ + G+K+ + G+ H VL T GE++ G + + QLG G
Sbjct: 76 GCLGLGDVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNGT 135
Query: 498 RGKASLPVRVAL---HEPVRALAAGYFHNLALTHKGEVYVWGASPQ-QVXXXXXXXXXEP 553
+P ++ ++ V +A G +H+L LT GEV+ WG + QV P
Sbjct: 136 TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP 195
Query: 554 SSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLG 613
T C+ V V I+ G + + G +Y WG N +GQLG
Sbjct: 196 RRVT-------------GCLQNKVV----VTIACGQMCCMAVVDTGEVYVWGYNGNGQLG 238
Query: 614 SGDRKQIQIPTEV 626
G+ P V
Sbjct: 239 LGNSGNQPTPCRV 251
>AL157813-1|CAH70795.1| 551|Homo sapiens regulator of chromosome
condensation (RCC1) and BTB (POZ) domain containing pro
protein.
Length = 551
Score = 107 bits (256), Expect = 3e-22
Identities = 71/222 (31%), Positives = 112/222 (50%), Gaps = 13/222 (5%)
Query: 320 TCGLAHWAVVSDGNARVMMASTPVNTELIGR-VIDVACGRHHTLILTENG-LYSAGDNTF 377
T G ++ + +G + ++T L + VI+VACG +H+L+LT +G +++ G N
Sbjct: 122 TWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNS 181
Query: 378 GQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGV 437
GQ+ L+ ++ +V +A G AV G + WG+
Sbjct: 182 GQVGSGSTVNQPIPRRVTG---CLQNKV-----VVTIACGQMCCMAVVDTGEVYVWGYNG 233
Query: 438 HGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQ 497
+GQLGLGN +Q TP V G +VQ V CG H+++LT G+++A GA+ +GQLGTG
Sbjct: 234 NGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGN 293
Query: 498 RGKASLPVRVALHEP--VRALAAGYFH-NLALTHKGEVYVWG 536
+ S P V + + + A H + A T G VY+WG
Sbjct: 294 KSNQSYPTPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMWG 335
Score = 96.3 bits (229), Expect = 5e-19
Identities = 64/236 (27%), Positives = 111/236 (47%), Gaps = 24/236 (10%)
Query: 402 RVRLAGGAPLVCVAAGHY-HSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTKFL 459
R+ G + C++ G H G + TWG + QLG G + P + T
Sbjct: 91 RLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLS 150
Query: 460 GRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVA---LHEPVRAL 516
++V V CG+ HS++LT GE++A G + GQ+G+G +P RV ++ V +
Sbjct: 151 NKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTI 210
Query: 517 AAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTT 576
A G +A+ GEVYVWG + + L + ++ P+
Sbjct: 211 ACGQMCCMAVVDTGEVYVWGYN---------------GNGQLGLGNSGNQ---PTPCRVA 252
Query: 577 NVRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTE 631
++G R+ +++ G+ H+ ++ + G +Y WG N GQLG+G++ PT V + +
Sbjct: 253 ALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKD 308
Score = 93.1 bits (221), Expect = 4e-18
Identities = 59/185 (31%), Positives = 86/185 (46%), Gaps = 11/185 (5%)
Query: 357 GRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAA 416
G H L TE +++ G N + QL +V + VA
Sbjct: 108 GPHIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQV--------IEVAC 159
Query: 417 GHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQ-SVGCGACHSVL 475
G YHS + + G + WG+ GQ+G G+ +Q P+ VT L KV ++ CG +
Sbjct: 160 GSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMA 219
Query: 476 LTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPVRA--LAAGYFHNLALTHKGEVY 533
+ GE++ G + GQLG G G P RVA + +R +A GY H L LT +G+VY
Sbjct: 220 VVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVY 279
Query: 534 VWGAS 538
WGA+
Sbjct: 280 AWGAN 284
Score = 69.7 bits (163), Expect = 5e-11
Identities = 54/193 (27%), Positives = 83/193 (43%), Gaps = 22/193 (11%)
Query: 439 GQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA-CHSVLLTRGGELWACGASVFGQLGTGQ 497
G LGLG++ P+ + G+K+ + G+ H VL T GE++ G + + QLG G
Sbjct: 76 GCLGLGDVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNGT 135
Query: 498 RGKASLPVRVAL---HEPVRALAAGYFHNLALTHKGEVYVWGASPQ-QVXXXXXXXXXEP 553
+P ++ ++ V +A G +H+L LT GEV+ WG + QV P
Sbjct: 136 TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP 195
Query: 554 SSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLG 613
T C+ V V I+ G + + G +Y WG N +GQLG
Sbjct: 196 RRVT-------------GCLQNKVV----VTIACGQMCCMAVVDTGEVYVWGYNGNGQLG 238
Query: 614 SGDRKQIQIPTEV 626
G+ P V
Sbjct: 239 LGNSGNQPTPCRV 251
>AF060219-1|AAC79987.1| 551|Homo sapiens RCC1-like G exchanging
factor RLG protein.
Length = 551
Score = 107 bits (256), Expect = 3e-22
Identities = 71/222 (31%), Positives = 112/222 (50%), Gaps = 13/222 (5%)
Query: 320 TCGLAHWAVVSDGNARVMMASTPVNTELIGR-VIDVACGRHHTLILTENG-LYSAGDNTF 377
T G ++ + +G + ++T L + VI+VACG +H+L+LT +G +++ G N
Sbjct: 122 TWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNS 181
Query: 378 GQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGV 437
GQ+ L+ ++ +V +A G AV G + WG+
Sbjct: 182 GQVGSGSTVNQPIPRRVTG---CLQNKV-----VVTIACGQMCCMAVVDTGEVYVWGYNG 233
Query: 438 HGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQ 497
+GQLGLGN +Q TP V G +VQ V CG H+++LT G+++A GA+ +GQLGTG
Sbjct: 234 NGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGN 293
Query: 498 RGKASLPVRVALHEP--VRALAAGYFH-NLALTHKGEVYVWG 536
+ S P V + + + A H + A T G VY+WG
Sbjct: 294 KSNQSYPTPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMWG 335
Score = 96.3 bits (229), Expect = 5e-19
Identities = 64/236 (27%), Positives = 111/236 (47%), Gaps = 24/236 (10%)
Query: 402 RVRLAGGAPLVCVAAGHY-HSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTKFL 459
R+ G + C++ G H G + TWG + QLG G + P + T
Sbjct: 91 RLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLS 150
Query: 460 GRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVA---LHEPVRAL 516
++V V CG+ HS++LT GE++A G + GQ+G+G +P RV ++ V +
Sbjct: 151 NKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTI 210
Query: 517 AAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTT 576
A G +A+ GEVYVWG + + L + ++ P+
Sbjct: 211 ACGQMCCMAVVDTGEVYVWGYN---------------GNGQLGLGNSGNQ---PTPCRVA 252
Query: 577 NVRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTE 631
++G R+ +++ G+ H+ ++ + G +Y WG N GQLG+G++ PT V + +
Sbjct: 253 ALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKD 308
Score = 93.1 bits (221), Expect = 4e-18
Identities = 59/185 (31%), Positives = 86/185 (46%), Gaps = 11/185 (5%)
Query: 357 GRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAA 416
G H L TE +++ G N + QL +V + VA
Sbjct: 108 GPHIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQV--------IEVAC 159
Query: 417 GHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQ-SVGCGACHSVL 475
G YHS + + G + WG+ GQ+G G+ +Q P+ VT L KV ++ CG +
Sbjct: 160 GSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMA 219
Query: 476 LTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPVRA--LAAGYFHNLALTHKGEVY 533
+ GE++ G + GQLG G G P RVA + +R +A GY H L LT +G+VY
Sbjct: 220 VVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVY 279
Query: 534 VWGAS 538
WGA+
Sbjct: 280 AWGAN 284
Score = 69.7 bits (163), Expect = 5e-11
Identities = 54/193 (27%), Positives = 83/193 (43%), Gaps = 22/193 (11%)
Query: 439 GQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA-CHSVLLTRGGELWACGASVFGQLGTGQ 497
G LGLG++ P+ + G+K+ + G+ H VL T GE++ G + + QLG G
Sbjct: 76 GCLGLGDVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNGT 135
Query: 498 RGKASLPVRVAL---HEPVRALAAGYFHNLALTHKGEVYVWGASPQ-QVXXXXXXXXXEP 553
+P ++ ++ V +A G +H+L LT GEV+ WG + QV P
Sbjct: 136 TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP 195
Query: 554 SSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLG 613
T C+ V V I+ G + + G +Y WG N +GQLG
Sbjct: 196 RRVT-------------GCLQNKVV----VTIACGQMCCMAVVDTGEVYVWGYNGNGQLG 238
Query: 614 SGDRKQIQIPTEV 626
G+ P V
Sbjct: 239 LGNSGNQPTPCRV 251
>AB209543-1|BAD92780.1| 556|Homo sapiens RCC1-like G exchanging
factor RLG variant protein.
Length = 556
Score = 107 bits (256), Expect = 3e-22
Identities = 71/222 (31%), Positives = 112/222 (50%), Gaps = 13/222 (5%)
Query: 320 TCGLAHWAVVSDGNARVMMASTPVNTELIGR-VIDVACGRHHTLILTENG-LYSAGDNTF 377
T G ++ + +G + ++T L + VI+VACG +H+L+LT +G +++ G N
Sbjct: 127 TWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNS 186
Query: 378 GQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGV 437
GQ+ L+ ++ +V +A G AV G + WG+
Sbjct: 187 GQVGSGSTVNQPIPRRVTG---CLQNKV-----VVTIACGQMCCMAVVDTGEVYVWGYNG 238
Query: 438 HGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQ 497
+GQLGLGN +Q TP V G +VQ V CG H+++LT G+++A GA+ +GQLGTG
Sbjct: 239 NGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGN 298
Query: 498 RGKASLPVRVALHEP--VRALAAGYFH-NLALTHKGEVYVWG 536
+ S P V + + + A H + A T G VY+WG
Sbjct: 299 KSNQSYPTPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMWG 340
Score = 96.3 bits (229), Expect = 5e-19
Identities = 64/236 (27%), Positives = 111/236 (47%), Gaps = 24/236 (10%)
Query: 402 RVRLAGGAPLVCVAAGHY-HSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTKFL 459
R+ G + C++ G H G + TWG + QLG G + P + T
Sbjct: 96 RLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLS 155
Query: 460 GRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVA---LHEPVRAL 516
++V V CG+ HS++LT GE++A G + GQ+G+G +P RV ++ V +
Sbjct: 156 NKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTI 215
Query: 517 AAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTT 576
A G +A+ GEVYVWG + + L + ++ P+
Sbjct: 216 ACGQMCCMAVVDTGEVYVWGYN---------------GNGQLGLGNSGNQ---PTPCRVA 257
Query: 577 NVRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTE 631
++G R+ +++ G+ H+ ++ + G +Y WG N GQLG+G++ PT V + +
Sbjct: 258 ALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKD 313
Score = 93.1 bits (221), Expect = 4e-18
Identities = 59/185 (31%), Positives = 86/185 (46%), Gaps = 11/185 (5%)
Query: 357 GRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAA 416
G H L TE +++ G N + QL +V + VA
Sbjct: 113 GPHIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQV--------IEVAC 164
Query: 417 GHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQ-SVGCGACHSVL 475
G YHS + + G + WG+ GQ+G G+ +Q P+ VT L KV ++ CG +
Sbjct: 165 GSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMA 224
Query: 476 LTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPVRA--LAAGYFHNLALTHKGEVY 533
+ GE++ G + GQLG G G P RVA + +R +A GY H L LT +G+VY
Sbjct: 225 VVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVY 284
Query: 534 VWGAS 538
WGA+
Sbjct: 285 AWGAN 289
Score = 69.7 bits (163), Expect = 5e-11
Identities = 54/193 (27%), Positives = 83/193 (43%), Gaps = 22/193 (11%)
Query: 439 GQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA-CHSVLLTRGGELWACGASVFGQLGTGQ 497
G LGLG++ P+ + G+K+ + G+ H VL T GE++ G + + QLG G
Sbjct: 81 GCLGLGDVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNGT 140
Query: 498 RGKASLPVRVAL---HEPVRALAAGYFHNLALTHKGEVYVWGASPQ-QVXXXXXXXXXEP 553
+P ++ ++ V +A G +H+L LT GEV+ WG + QV P
Sbjct: 141 TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP 200
Query: 554 SSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLG 613
T C+ V V I+ G + + G +Y WG N +GQLG
Sbjct: 201 RRVT-------------GCLQNKVV----VTIACGQMCCMAVVDTGEVYVWGYNGNGQLG 243
Query: 614 SGDRKQIQIPTEV 626
G+ P V
Sbjct: 244 LGNSGNQPTPCRV 256
>AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protein 1
protein.
Length = 1024
Score = 106 bits (254), Expect = 4e-22
Identities = 67/237 (28%), Positives = 108/237 (45%), Gaps = 21/237 (8%)
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN-IDDQWTPQLVTKFLGRKVQSVGCG 469
++ + G YHS A+ GG L WG +HGQLG+G TPQ+V G + + G
Sbjct: 140 IIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQISAG 199
Query: 470 ACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLALT 527
HS+ L+ G +++ G + GQLG G P + ++ V +A G H+ LT
Sbjct: 200 EAHSMALSMSGNIYSWGKNECGQLGLGHTESKDDPSLIEGLDNQKVEFVACGGSHSALLT 259
Query: 528 HKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISA 587
G ++ +GA H+ L P C+ V R+ QI+
Sbjct: 260 QDGLLFTFGAGKHGQLG----------------HNSTQNELRP-CLVAELVGYRVTQIAC 302
Query: 588 G-WHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMKSDSEK 643
G WH ++++G ++++G DGQLG+G + +P VK+ + + SEK
Sbjct: 303 GRWHTLAYVSDLGKVFSFGSGKDGQLGNGGTRDQLMPLPVKVSSSEELKLESHTSEK 359
Score = 98.7 bits (235), Expect = 9e-20
Identities = 63/192 (32%), Positives = 94/192 (48%), Gaps = 12/192 (6%)
Query: 350 RVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
++I + CG +H+L L++ G L++ G N GQL V G
Sbjct: 139 KIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQI--------VEHLAG 190
Query: 409 APLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGC 468
PL ++AG HS A+ G + +WG GQLGLG+ + + P L+ +KV+ V C
Sbjct: 191 VPLAQISAGEAHSMALSMSGNIYSWGKNECGQLGLGHTESKDDPSLIEGLDNQKVEFVAC 250
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVA--LHEPVRALAAGYFHNLA- 525
G HS LLT+ G L+ GA GQLG P VA + V +A G +H LA
Sbjct: 251 GGSHSALLTQDGLLFTFGAGKHGQLGHNSTQNELRPCLVAELVGYRVTQIACGRWHTLAY 310
Query: 526 LTHKGEVYVWGA 537
++ G+V+ +G+
Sbjct: 311 VSDLGKVFSFGS 322
Score = 67.3 bits (157), Expect = 3e-10
Identities = 43/156 (27%), Positives = 79/156 (50%), Gaps = 20/156 (12%)
Query: 461 RKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALH---EPVRALA 517
+K+ + CG HS+ L++GGEL+A G ++ GQLG G++ ++ ++ H P+ ++
Sbjct: 138 KKIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQIS 197
Query: 518 AGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTN 577
AG H++AL+ G +Y WG + E L + D PS ++ +
Sbjct: 198 AGEAHSMALSMSGNIYSWGKN-------------ECGQLGLGHTESKD---DPSLIEGLD 241
Query: 578 VRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLG 613
++ ++ G HS ++ G ++T+G GQLG
Sbjct: 242 -NQKVEFVACGGSHSALLTQDGLLFTFGAGKHGQLG 276
Score = 39.9 bits (89), Expect = 0.044
Identities = 15/35 (42%), Positives = 23/35 (65%)
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSG 615
+I+QI+ G +HS ++ G ++ WG N GQLG G
Sbjct: 139 KIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVG 173
>AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligase
protein.
Length = 1024
Score = 105 bits (253), Expect = 6e-22
Identities = 67/237 (28%), Positives = 107/237 (45%), Gaps = 21/237 (8%)
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN-IDDQWTPQLVTKFLGRKVQSVGCG 469
++ + G YHS A+ GG L WG +HGQLG+G TPQ+V G + + G
Sbjct: 140 IIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQISAG 199
Query: 470 ACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLALT 527
HS L+ G +++ G + GQLG G P + ++ V +A G H+ LT
Sbjct: 200 EAHSTALSMSGNIYSWGKNECGQLGLGHTESKDDPSLIEGLDNQKVEFVACGGSHSALLT 259
Query: 528 HKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISA 587
G ++ +GA H+ L P C+ V R+ QI+
Sbjct: 260 QDGLLFTFGAGKHGQLG----------------HNSTQNELRP-CLVAELVGYRVTQIAC 302
Query: 588 G-WHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMKSDSEK 643
G WH ++++G ++++G DGQLG+G + +P VK+ + + SEK
Sbjct: 303 GRWHTLAYVSDLGKVFSFGSGKDGQLGNGGTRDQLMPLPVKVSSSEELKLESHTSEK 359
Score = 99.1 bits (236), Expect = 7e-20
Identities = 63/192 (32%), Positives = 94/192 (48%), Gaps = 12/192 (6%)
Query: 350 RVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
++I + CG +H+L L++ G L++ G N GQL V G
Sbjct: 139 KIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQI--------VEHLAG 190
Query: 409 APLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGC 468
PL ++AG HS A+ G + +WG GQLGLG+ + + P L+ +KV+ V C
Sbjct: 191 VPLAQISAGEAHSTALSMSGNIYSWGKNECGQLGLGHTESKDDPSLIEGLDNQKVEFVAC 250
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVA--LHEPVRALAAGYFHNLA- 525
G HS LLT+ G L+ GA GQLG P VA + V +A G +H LA
Sbjct: 251 GGSHSALLTQDGLLFTFGAGKHGQLGHNSTQNELRPCLVAELVGYRVTQIACGRWHTLAY 310
Query: 526 LTHKGEVYVWGA 537
++ G+V+ +G+
Sbjct: 311 VSDLGKVFSFGS 322
Score = 66.1 bits (154), Expect = 6e-10
Identities = 43/156 (27%), Positives = 78/156 (50%), Gaps = 20/156 (12%)
Query: 461 RKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALH---EPVRALA 517
+K+ + CG HS+ L++GGEL+A G ++ GQLG G++ ++ ++ H P+ ++
Sbjct: 138 KKIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQIS 197
Query: 518 AGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTN 577
AG H+ AL+ G +Y WG + E L + D PS ++ +
Sbjct: 198 AGEAHSTALSMSGNIYSWGKN-------------ECGQLGLGHTESKD---DPSLIEGLD 241
Query: 578 VRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLG 613
++ ++ G HS ++ G ++T+G GQLG
Sbjct: 242 -NQKVEFVACGGSHSALLTQDGLLFTFGAGKHGQLG 276
Score = 39.9 bits (89), Expect = 0.044
Identities = 15/35 (42%), Positives = 23/35 (65%)
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSG 615
+I+QI+ G +HS ++ G ++ WG N GQLG G
Sbjct: 139 KIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVG 173
>U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein.
Length = 4861
Score = 104 bits (250), Expect = 1e-21
Identities = 85/317 (26%), Positives = 144/317 (45%), Gaps = 37/317 (11%)
Query: 319 LTCGLAHWAVVSDGNARVMMASTPVNTELIGRVID---VACGRH-HTLILTENG-LYSAG 373
L CG + + GN+ + T ++ L G V+ +CG H++ LTE+G ++S G
Sbjct: 4049 LACGEGSYGRLGQGNSDDLHVLTVISA-LQGFVVTQLVTSCGSDGHSMALTESGEVFSWG 4107
Query: 374 DNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTW 433
D +G+L ++ G +V ++ G HSA V + G+L T+
Sbjct: 4108 DGDYGKLGHGNSDRQRRPR---------QIEALQGEEVVQMSCGFKHSAVVTSDGKLFTF 4158
Query: 434 GWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGEL-WACGASVFGQ 492
G G +G+LGLGN ++ P+ VT G ++ V CG H++ ++ G + WA G +G+
Sbjct: 4159 GNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYGK 4218
Query: 493 LGTGQRGKASLP--VRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXX 550
LG G S P + V ++ +A G ++ALT G VY +G + +
Sbjct: 4219 LGLGNSTAKSSPQKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQD-RLIGLPEGRAR 4277
Query: 551 XEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQ-ISAGWHHSCIINNMGSIYTWGLNFD 609
+P + G I++ ++ G H+ + + G +Y WG N +
Sbjct: 4278 NHNRPQQIPV-----------------LAGVIIEDVAVGAEHTLALASNGDVYAWGSNSE 4320
Query: 610 GQLGSGDRKQIQIPTEV 626
GQLG G ++ PT V
Sbjct: 4321 GQLGLGHTNHVREPTLV 4337
Score = 98.7 bits (235), Expect = 9e-20
Identities = 81/261 (31%), Positives = 116/261 (44%), Gaps = 32/261 (12%)
Query: 360 HTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGH 418
HTL T G ++S GD +G+L +++ L G +VCV+AG+
Sbjct: 469 HTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPK-------LIQGPLQGKV-VVCVSAGY 520
Query: 419 YHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTR 478
HSAAV G L TWG G G+LG G+ + + P LV V V CG+ H++ L++
Sbjct: 521 RHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDI--SNVGEVSCGSSHTIALSK 578
Query: 479 GGE-LWACGASVFGQLGTGQRGKASLP-VRVALHEP-VRALAAGYFHNLALTHKGEVYVW 535
G +W+ G G+LG G + P V AL +R + AG +LALT G+VY W
Sbjct: 579 DGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAW 638
Query: 536 GASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCII 595
G L L P ++ RIV +S G H +
Sbjct: 639 GC-----------------GACLGCGSSEATALRPKLIEEL-AATRIVDVSIGDSHCLAL 680
Query: 596 NNMGSIYTWGLNFDGQLGSGD 616
++ +Y WG N GQ G G+
Sbjct: 681 SHDNEVYAWGNNSMGQCGQGN 701
Score = 84.2 bits (199), Expect = 2e-15
Identities = 54/185 (29%), Positives = 87/185 (47%), Gaps = 10/185 (5%)
Query: 354 VACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLV 412
V CG++ T ++ NG + + G+ ++G+L + +L
Sbjct: 4032 VICGQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLVTS---- 4087
Query: 413 CVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACH 472
C + GH S A+ G + +WG G +G+LG GN D Q P+ + G +V + CG H
Sbjct: 4088 CGSDGH--SMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKH 4145
Query: 473 SVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHE--PVRALAAGYFHNLALTHKG 530
S ++T G+L+ G +G+LG G LP RV E + +A G H LA++ G
Sbjct: 4146 SAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLNHTLAVSADG 4205
Query: 531 EVYVW 535
+ VW
Sbjct: 4206 SM-VW 4209
Score = 81.4 bits (192), Expect = 1e-14
Identities = 60/212 (28%), Positives = 99/212 (46%), Gaps = 14/212 (6%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
V+ ++CG H+ ++T +G L++ G+ +G+L RV G
Sbjct: 4136 VVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPE---------RVTALEGY 4186
Query: 410 PLVCVAAGHYHSAAVDAGGRLL-TWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGC 468
+ VA G H+ AV A G ++ +G G +G+LGLGN + +PQ + G ++ V C
Sbjct: 4187 QIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKIDVLCGIGIKKVAC 4246
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPV--RALAAGYFHNLAL 526
G SV LT+ G ++ G L G+ + P ++ + V +A G H LAL
Sbjct: 4247 GTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVIIEDVAVGAEHTLAL 4306
Query: 527 THKGEVYVWGASPQ-QVXXXXXXXXXEPSSPT 557
G+VY WG++ + Q+ EP+ T
Sbjct: 4307 ASNGDVYAWGSNSEGQLGLGHTNHVREPTLVT 4338
Score = 71.7 bits (168), Expect = 1e-11
Identities = 58/221 (26%), Positives = 104/221 (47%), Gaps = 26/221 (11%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA--- 470
+ AG Y + + G + G G +G+LGLG+ ++Q T + +T R ++ V
Sbjct: 408 IEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSD 467
Query: 471 CHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALH-EPVRALAAGYFHNLALT 527
H++ T GE+++ G +G+LG G P ++ L + V ++AGY H+ A+T
Sbjct: 468 GHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVT 527
Query: 528 HKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISA 587
GE+Y WG E L D N R + D +NV ++S
Sbjct: 528 EDGELYTWG---------------EGDFGRLGHGDSNSRNIPTLVKDISNVG----EVSC 568
Query: 588 GWHHSCIINNMG-SIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
G H+ ++ G +++++G +G+LG GD ++ P ++
Sbjct: 569 GSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIE 609
Score = 66.1 bits (154), Expect = 6e-10
Identities = 53/201 (26%), Positives = 85/201 (42%), Gaps = 25/201 (12%)
Query: 433 WGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQ 492
WG QL G + P+L F Q++ G + +++ G + ACG +G+
Sbjct: 377 WGSNSSHQLVEGTQEKILQPKLAPSF--SDAQTIEAGQYCTFVISTDGSVRACGKGSYGR 434
Query: 493 LGTGQRGKASLPVRVAL--HEPVRALAAGY---FHNLALTHKGEVYVWGASPQQVXXXXX 547
LG G S ++ H ++ +++ H LA T +GEV+ WG
Sbjct: 435 LGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLG--- 491
Query: 548 XXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQ-ISAGWHHSCIINNMGSIYTWGL 606
H ++ P + ++G++V +SAG+ HS + G +YTWG
Sbjct: 492 -------------HGNSSTQKYPKLIQGP-LQGKVVVCVSAGYRHSAAVTEDGELYTWGE 537
Query: 607 NFDGQLGSGDRKQIQIPTEVK 627
G+LG GD IPT VK
Sbjct: 538 GDFGRLGHGDSNSRNIPTLVK 558
Score = 61.3 bits (142), Expect = 2e-08
Identities = 53/199 (26%), Positives = 82/199 (41%), Gaps = 25/199 (12%)
Query: 433 WGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQ 492
WG G HGQL + P F + Q V CG + ++ G + ACG +G+
Sbjct: 4002 WGAGRHGQLAEAG-RNVMVPAAAPSF--SQAQQVICGQNCTFVIQANGTVLACGEGSYGR 4058
Query: 493 LGTGQRGKAS-LPVRVALH----EPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXX 547
LG G L V AL + H++ALT GEV+ WG
Sbjct: 4059 LGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLG--- 4115
Query: 548 XXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLN 607
H ++DR P ++ +VQ+S G+ HS ++ + G ++T+G
Sbjct: 4116 -------------HGNSDRQRRPRQIEALQGE-EVVQMSCGFKHSAVVTSDGKLFTFGNG 4161
Query: 608 FDGQLGSGDRKQIQIPTEV 626
G+LG G+ ++P V
Sbjct: 4162 DYGRLGLGNTSNKKLPERV 4180
Score = 54.8 bits (126), Expect = 1e-06
Identities = 38/125 (30%), Positives = 56/125 (44%), Gaps = 10/125 (8%)
Query: 354 VACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLV 412
VACG ++ LT++G +Y TFGQ ++ + G +
Sbjct: 4244 VACGTQFSVALTKDGHVY-----TFGQ----DRLIGLPEGRARNHNRPQQIPVLAGVIIE 4294
Query: 413 CVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACH 472
VA G H+ A+ + G + WG GQLGLG+ + P LVT G+ V+ + G CH
Sbjct: 4295 DVAVGAEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVTGLQGKNVRQISAGRCH 4354
Query: 473 SVLLT 477
S T
Sbjct: 4355 SAAWT 4359
Score = 54.4 bits (125), Expect = 2e-06
Identities = 52/203 (25%), Positives = 91/203 (44%), Gaps = 21/203 (10%)
Query: 331 DGNARVMMASTPVNTELIGRVIDVACGRHHTLILTENG--LYSAGDNTFGQLXXXXXXXX 388
D N+R + P + I V +V+CG HT+ L+++G ++S G G+L
Sbjct: 547 DSNSR----NIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRV 602
Query: 389 XXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNID- 447
+ G + V AG S A+ + G++ WG G LG G+ +
Sbjct: 603 YKPKV---------IEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGAC--LGCGSSEA 651
Query: 448 DQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTG-QRGKASLPVR 506
P+L+ + ++ V G H + L+ E++A G + GQ G G G + P +
Sbjct: 652 TALRPKLIEELAATRIVDVSIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKK 711
Query: 507 VALHE--PVRALAAGYFHNLALT 527
V+ + ++ ++AG H+LA T
Sbjct: 712 VSGLDGIAIQQISAGTSHSLAWT 734
>D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein.
Length = 1054
Score = 104 bits (249), Expect = 2e-21
Identities = 88/306 (28%), Positives = 140/306 (45%), Gaps = 38/306 (12%)
Query: 317 RSLTCGLAHWAVVSDG---NARVMMASTPVNTELIGRVI-DVACGRHHTLILTENG-LYS 371
R++ C +W++ G N + ++A V + R + +VACG +H++ L E+G +Y+
Sbjct: 3 RTMLCW-GYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYT 61
Query: 372 AGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLL 431
G NT GQL ++ V A G HS A+ G+L
Sbjct: 62 CGLNTKGQLGHEREGNKPEQIGALADQHIIHV-----------ACGESHSLALSDRGQLF 110
Query: 432 TWGWGVHGQLGLGNIDDQ-WTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVF 490
+WG G GQLGL +D P+L+ K + + V CG H + L G+ + G +
Sbjct: 111 SWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSH 170
Query: 491 GQLGTGQR-GKASLPVRVALHE--PVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXX 547
GQLG G+ + P RV E P+ +AAG H+ AL+ G V+ WG +
Sbjct: 171 GQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMN--------- 221
Query: 548 XXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLN 607
++ L D+ DR +P V + ++V IS G H+ ++ G ++T+G
Sbjct: 222 ------NAGQLGLSDEKDRE-SPCHVKLLRTQ-KVVYISCGEEHTAVLTKSGGVFTFGAG 273
Query: 608 FDGQLG 613
GQLG
Sbjct: 274 SCGQLG 279
Score = 95.1 bits (226), Expect = 1e-18
Identities = 81/282 (28%), Positives = 120/282 (42%), Gaps = 30/282 (10%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
+I VACG H+L L++ G L+S G + GQL ++
Sbjct: 90 IIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRL--------IQKLNQQ 141
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN-IDDQWTPQLVTKFLGRKVQSVGC 468
++ V+ G++H A+ A G+ TWG HGQLGLG Q +PQ V G + V
Sbjct: 142 TILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAA 201
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVAL--HEPVRALAAGYFHNLAL 526
G HS L+ G ++ G + GQLG P V L + V ++ G H L
Sbjct: 202 GGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVL 261
Query: 527 THKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQIS 586
T G V+ +GA S L HD + + P V + + QI+
Sbjct: 262 TKSGGVFTFGAG---------------SCGQLG-HDSMNDEVNPRRV-LELMGSEVTQIA 304
Query: 587 AGWHHS-CIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
G H+ + + G IY +G GQLG+G ++ P+ VK
Sbjct: 305 CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVK 346
Score = 87.8 bits (208), Expect = 2e-16
Identities = 71/224 (31%), Positives = 97/224 (43%), Gaps = 18/224 (8%)
Query: 323 LAHWAVVSDGNARVMMASTPVNT-ELIGR-----VIDVACGRHHTLILTENG-LYSAGDN 375
L W SDG +M V LI + ++ V+CG H L L +G ++ G N
Sbjct: 109 LFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKN 168
Query: 376 TFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGW 435
+ GQL RVR G PL VAAG HS A+ G + WG
Sbjct: 169 SHGQLGLGKEFPSQASPQ--------RVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGM 220
Query: 436 GVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGT 495
GQLGL + D+ +P V +KV + CG H+ +LT+ G ++ GA GQLG
Sbjct: 221 NNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGH 280
Query: 496 GQRGKASLPVRV--ALHEPVRALAAGYFHNLA-LTHKGEVYVWG 536
P RV + V +A G H LA + G +Y +G
Sbjct: 281 DSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFG 324
Score = 73.7 bits (173), Expect = 3e-12
Identities = 61/223 (27%), Positives = 102/223 (45%), Gaps = 24/223 (10%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHS 473
VA G HS + G + T G GQLG ++ P+ + + + V CG HS
Sbjct: 43 VACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGNK--PEQIGALADQHIIHVACGESHS 100
Query: 474 VLLTRGGELWACGASVFGQLGT-GQRGKASLP--VRVALHEPVRALAAGYFHNLALTHKG 530
+ L+ G+L++ GA GQLG ++P ++ + + ++ G +H LAL G
Sbjct: 101 LALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADG 160
Query: 531 EVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRG-RIVQISAGW 589
+ + WG + S L + +P V ++ G + Q++AG
Sbjct: 161 QFFTWGKN---------------SHGQLGLGKEFPSQASPQRV--RSLEGIPLAQVAAGG 203
Query: 590 HHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK-IRTE 631
HS ++ G+++ WG+N GQLG D K + P VK +RT+
Sbjct: 204 AHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQ 246
Score = 41.1 bits (92), Expect = 0.019
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 11/98 (11%)
Query: 350 RVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
+V+ ++CG HT +LT++G +++ G + GQL RV G
Sbjct: 247 KVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPR---------RVLELMG 297
Query: 409 APLVCVAAGHYHSAA-VDAGGRLLTWGWGVHGQLGLGN 445
+ + +A G H+ A V + G + +G G GQLG G+
Sbjct: 298 SEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLGTGH 335
Score = 32.7 bits (71), Expect = 6.7
Identities = 13/32 (40%), Positives = 23/32 (71%), Gaps = 1/32 (3%)
Query: 659 VGCGGDFTVYIDDDGRIYSTG-NTHLQISNEK 689
V CGG+ +V++ +DG +Y+ G NT Q+ +E+
Sbjct: 43 VACGGNHSVFLLEDGEVYTCGLNTKGQLGHER 74
>BC038960-1|AAH38960.1| 368|Homo sapiens HERC3 protein protein.
Length = 368
Score = 103 bits (248), Expect = 2e-21
Identities = 81/268 (30%), Positives = 123/268 (45%), Gaps = 33/268 (12%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
V +VACG +H++ L E+G +Y+ G NT GQL ++ V
Sbjct: 36 VKEVACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGNKPEQIGALADQHIIHV------ 89
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQ-WTPQLVTKFLGRKVQSVGC 468
A G HS A+ G+L +WG G GQLGL +D P+L+ K + + V C
Sbjct: 90 -----ACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSC 144
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQR-GKASLPVRVALHE--PVRALAAGYFHNLA 525
G H + L G+ + G + GQLG G+ + P RV E P+ +AAG H+ A
Sbjct: 145 GNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFA 204
Query: 526 LTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQI 585
L+ G V+ WG + ++ L D+ DR +P V + ++V I
Sbjct: 205 LSLSGAVFGWGMN---------------NAGQLGLSDEKDRE-SPCHVKLLRTQ-KVVYI 247
Query: 586 SAGWHHSCIINNMGSIYTWGLNFDGQLG 613
S G H+ ++ G ++T+G GQLG
Sbjct: 248 SCGEEHTAVLTKSGGVFTFGAGSCGQLG 275
Score = 95.1 bits (226), Expect = 1e-18
Identities = 81/282 (28%), Positives = 120/282 (42%), Gaps = 30/282 (10%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
+I VACG H+L L++ G L+S G + GQL ++
Sbjct: 86 IIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRL--------IQKLNQQ 137
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN-IDDQWTPQLVTKFLGRKVQSVGC 468
++ V+ G++H A+ A G+ TWG HGQLGLG Q +PQ V G + V
Sbjct: 138 TILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAA 197
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVAL--HEPVRALAAGYFHNLAL 526
G HS L+ G ++ G + GQLG P V L + V ++ G H L
Sbjct: 198 GGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVL 257
Query: 527 THKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQIS 586
T G V+ +GA S L HD + + P V + + QI+
Sbjct: 258 TKSGGVFTFGAG---------------SCGQLG-HDSMNDEVNPRRV-LELMGSEVTQIA 300
Query: 587 AGWHHS-CIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
G H+ + + G IY +G GQLG+G ++ P+ VK
Sbjct: 301 CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVK 342
Score = 87.8 bits (208), Expect = 2e-16
Identities = 71/224 (31%), Positives = 97/224 (43%), Gaps = 18/224 (8%)
Query: 323 LAHWAVVSDGNARVMMASTPVNT-ELIGR-----VIDVACGRHHTLILTENG-LYSAGDN 375
L W SDG +M V LI + ++ V+CG H L L +G ++ G N
Sbjct: 105 LFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKN 164
Query: 376 TFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGW 435
+ GQL RVR G PL VAAG HS A+ G + WG
Sbjct: 165 SHGQLGLGKEFPSQASPQ--------RVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGM 216
Query: 436 GVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGT 495
GQLGL + D+ +P V +KV + CG H+ +LT+ G ++ GA GQLG
Sbjct: 217 NNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGH 276
Query: 496 GQRGKASLPVRV--ALHEPVRALAAGYFHNLA-LTHKGEVYVWG 536
P RV + V +A G H LA + G +Y +G
Sbjct: 277 DSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFG 320
Score = 83.8 bits (198), Expect = 3e-15
Identities = 57/188 (30%), Positives = 83/188 (44%), Gaps = 18/188 (9%)
Query: 430 LLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLG-RKVQSVGCGACHSVLLTRGGELWACGA 487
+L WG+ GQ G+ N+ V F+ R V+ V CG HSV L GE++ CG
Sbjct: 1 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL 60
Query: 488 SVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXX 547
+ GQLG + G + + + +A G H+LAL+ +G+++ WGA
Sbjct: 61 NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAG--------- 111
Query: 548 XXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLN 607
S L D P + N + I+Q+S G H + G +TWG N
Sbjct: 112 ------SDGQLGLMTTEDSVAVPRLIQKLN-QQTILQVSCGNWHCLALAADGQFFTWGKN 164
Query: 608 FDGQLGSG 615
GQLG G
Sbjct: 165 SHGQLGLG 172
Score = 73.7 bits (173), Expect = 3e-12
Identities = 61/223 (27%), Positives = 102/223 (45%), Gaps = 24/223 (10%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHS 473
VA G HS + G + T G GQLG ++ P+ + + + V CG HS
Sbjct: 39 VACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGNK--PEQIGALADQHIIHVACGESHS 96
Query: 474 VLLTRGGELWACGASVFGQLGT-GQRGKASLP--VRVALHEPVRALAAGYFHNLALTHKG 530
+ L+ G+L++ GA GQLG ++P ++ + + ++ G +H LAL G
Sbjct: 97 LALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADG 156
Query: 531 EVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRG-RIVQISAGW 589
+ + WG + S L + +P V ++ G + Q++AG
Sbjct: 157 QFFTWGKN---------------SHGQLGLGKEFPSQASPQRV--RSLEGIPLAQVAAGG 199
Query: 590 HHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK-IRTE 631
HS ++ G+++ WG+N GQLG D K + P VK +RT+
Sbjct: 200 AHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQ 242
Score = 41.1 bits (92), Expect = 0.019
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 11/98 (11%)
Query: 350 RVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
+V+ ++CG HT +LT++G +++ G + GQL RV G
Sbjct: 243 KVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPR---------RVLELMG 293
Query: 409 APLVCVAAGHYHSAA-VDAGGRLLTWGWGVHGQLGLGN 445
+ + +A G H+ A V + G + +G G GQLG G+
Sbjct: 294 SEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLGTGH 331
Score = 32.7 bits (71), Expect = 6.7
Identities = 13/32 (40%), Positives = 23/32 (71%), Gaps = 1/32 (3%)
Query: 659 VGCGGDFTVYIDDDGRIYSTG-NTHLQISNEK 689
V CGG+ +V++ +DG +Y+ G NT Q+ +E+
Sbjct: 39 VACGGNHSVFLLEDGEVYTCGLNTKGQLGHER 70
>AC098582-1|AAY41038.1| 382|Homo sapiens unknown protein.
Length = 382
Score = 103 bits (248), Expect = 2e-21
Identities = 81/268 (30%), Positives = 123/268 (45%), Gaps = 33/268 (12%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
V +VACG +H++ L E+G +Y+ G NT GQL ++ V
Sbjct: 36 VKEVACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGNKPEQIGALADQHIIHV------ 89
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQ-WTPQLVTKFLGRKVQSVGC 468
A G HS A+ G+L +WG G GQLGL +D P+L+ K + + V C
Sbjct: 90 -----ACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSC 144
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQR-GKASLPVRVALHE--PVRALAAGYFHNLA 525
G H + L G+ + G + GQLG G+ + P RV E P+ +AAG H+ A
Sbjct: 145 GNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFA 204
Query: 526 LTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQI 585
L+ G V+ WG + ++ L D+ DR +P V + ++V I
Sbjct: 205 LSLSGAVFGWGMN---------------NAGQLGLSDEKDRE-SPCHVKLLRTQ-KVVYI 247
Query: 586 SAGWHHSCIINNMGSIYTWGLNFDGQLG 613
S G H+ ++ G ++T+G GQLG
Sbjct: 248 SCGEEHTAVLTKSGGVFTFGAGSCGQLG 275
Score = 95.1 bits (226), Expect = 1e-18
Identities = 81/282 (28%), Positives = 120/282 (42%), Gaps = 30/282 (10%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
+I VACG H+L L++ G L+S G + GQL ++
Sbjct: 86 IIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRL--------IQKLNQQ 137
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN-IDDQWTPQLVTKFLGRKVQSVGC 468
++ V+ G++H A+ A G+ TWG HGQLGLG Q +PQ V G + V
Sbjct: 138 TILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAA 197
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVAL--HEPVRALAAGYFHNLAL 526
G HS L+ G ++ G + GQLG P V L + V ++ G H L
Sbjct: 198 GGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVL 257
Query: 527 THKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQIS 586
T G V+ +GA S L HD + + P V + + QI+
Sbjct: 258 TKSGGVFTFGAG---------------SCGQLG-HDSMNDEVNPRRV-LELMGSEVTQIA 300
Query: 587 AGWHHS-CIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
G H+ + + G IY +G GQLG+G ++ P+ VK
Sbjct: 301 CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVK 342
Score = 87.8 bits (208), Expect = 2e-16
Identities = 71/224 (31%), Positives = 97/224 (43%), Gaps = 18/224 (8%)
Query: 323 LAHWAVVSDGNARVMMASTPVNT-ELIGR-----VIDVACGRHHTLILTENG-LYSAGDN 375
L W SDG +M V LI + ++ V+CG H L L +G ++ G N
Sbjct: 105 LFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKN 164
Query: 376 TFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGW 435
+ GQL RVR G PL VAAG HS A+ G + WG
Sbjct: 165 SHGQLGLGKEFPSQASPQ--------RVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGM 216
Query: 436 GVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGT 495
GQLGL + D+ +P V +KV + CG H+ +LT+ G ++ GA GQLG
Sbjct: 217 NNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGH 276
Query: 496 GQRGKASLPVRV--ALHEPVRALAAGYFHNLA-LTHKGEVYVWG 536
P RV + V +A G H LA + G +Y +G
Sbjct: 277 DSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFG 320
Score = 83.8 bits (198), Expect = 3e-15
Identities = 57/188 (30%), Positives = 83/188 (44%), Gaps = 18/188 (9%)
Query: 430 LLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLG-RKVQSVGCGACHSVLLTRGGELWACGA 487
+L WG+ GQ G+ N+ V F+ R V+ V CG HSV L GE++ CG
Sbjct: 1 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL 60
Query: 488 SVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXX 547
+ GQLG + G + + + +A G H+LAL+ +G+++ WGA
Sbjct: 61 NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAG--------- 111
Query: 548 XXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLN 607
S L D P + N + I+Q+S G H + G +TWG N
Sbjct: 112 ------SDGQLGLMTTEDSVAVPRLIQKLN-QQTILQVSCGNWHCLALAADGQFFTWGKN 164
Query: 608 FDGQLGSG 615
GQLG G
Sbjct: 165 SHGQLGLG 172
Score = 73.7 bits (173), Expect = 3e-12
Identities = 61/223 (27%), Positives = 102/223 (45%), Gaps = 24/223 (10%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHS 473
VA G HS + G + T G GQLG ++ P+ + + + V CG HS
Sbjct: 39 VACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGNK--PEQIGALADQHIIHVACGESHS 96
Query: 474 VLLTRGGELWACGASVFGQLGT-GQRGKASLP--VRVALHEPVRALAAGYFHNLALTHKG 530
+ L+ G+L++ GA GQLG ++P ++ + + ++ G +H LAL G
Sbjct: 97 LALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADG 156
Query: 531 EVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRG-RIVQISAGW 589
+ + WG + S L + +P V ++ G + Q++AG
Sbjct: 157 QFFTWGKN---------------SHGQLGLGKEFPSQASPQRV--RSLEGIPLAQVAAGG 199
Query: 590 HHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK-IRTE 631
HS ++ G+++ WG+N GQLG D K + P VK +RT+
Sbjct: 200 AHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQ 242
Score = 41.1 bits (92), Expect = 0.019
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 11/98 (11%)
Query: 350 RVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
+V+ ++CG HT +LT++G +++ G + GQL RV G
Sbjct: 243 KVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPR---------RVLELMG 293
Query: 409 APLVCVAAGHYHSAA-VDAGGRLLTWGWGVHGQLGLGN 445
+ + +A G H+ A V + G + +G G GQLG G+
Sbjct: 294 SEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLGTGH 331
Score = 32.7 bits (71), Expect = 6.7
Identities = 13/32 (40%), Positives = 23/32 (71%), Gaps = 1/32 (3%)
Query: 659 VGCGGDFTVYIDDDGRIYSTG-NTHLQISNEK 689
V CGG+ +V++ +DG +Y+ G NT Q+ +E+
Sbjct: 39 VACGGNHSVFLLEDGEVYTCGLNTKGQLGHER 70
>BC038104-1|AAH38104.1| 355|Homo sapiens RCBTB1 protein protein.
Length = 355
Score = 102 bits (245), Expect = 6e-21
Identities = 70/216 (32%), Positives = 105/216 (48%), Gaps = 13/216 (6%)
Query: 326 WAVVSDGNARVMMASTPVNTEL-IGRVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXX 383
++ + +G +A+ V T L I +V++VACG HH++ L +G +++ G N GQ+
Sbjct: 104 YSQLGNGTTNQGIATVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSG 163
Query: 384 XXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGL 443
+ RV V +A G S AV G + WG+ +GQLGL
Sbjct: 164 STANQPTPRKVTNCLHIKRV--------VGIACGQTSSMAVLDNGEVYGWGYNGNGQLGL 215
Query: 444 GNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASL 503
GN +Q TP V V + CG H++ LT G L+A GA+ +GQLGTG +
Sbjct: 216 GNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLS 275
Query: 504 PVRVALH-EPVRALAAGY--FHNLALTHKGEVYVWG 536
P + + E V +AA + + A T G VY+WG
Sbjct: 276 PAHIMVEKERVVEIAACHSAHTSAAKTQGGHVYMWG 311
Score = 101 bits (242), Expect = 1e-20
Identities = 65/183 (35%), Positives = 92/183 (50%), Gaps = 12/183 (6%)
Query: 360 HTLILTENGL-YSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGH 418
H L+ TE+G+ Y+ G N + QL + +V V VA G
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIATVQVCTNLLIKQV--------VEVACGS 137
Query: 419 YHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLG-RKVQSVGCGACHSVLLT 477
+HS A+ A G + WG+ GQ+G G+ +Q TP+ VT L ++V + CG S+ +
Sbjct: 138 HHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVL 197
Query: 478 RGGELWACGASVFGQLGTGQRGKASLPVRVA-LHEP-VRALAAGYFHNLALTHKGEVYVW 535
GE++ G + GQLG G G PVRVA LH V + GY H LALT +G +Y W
Sbjct: 198 DNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAW 257
Query: 536 GAS 538
GA+
Sbjct: 258 GAN 260
Score = 81.0 bits (191), Expect = 2e-14
Identities = 60/208 (28%), Positives = 94/208 (45%), Gaps = 21/208 (10%)
Query: 428 GRLLTWGWGVHGQLGLGNIDDQW-TPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACG 486
G + WG + QLG G + T Q+ T L ++V V CG+ HS+ L GE++A G
Sbjct: 94 GVVYAWGHNGYSQLGNGTTNQGIATVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWG 153
Query: 487 ASVFGQLGTGQRGKASLPVRVA--LH-EPVRALAAGYFHNLALTHKGEVYVWGASPQQVX 543
+ GQ+G+G P +V LH + V +A G ++A+ GEVY WG +
Sbjct: 154 YNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQL 213
Query: 544 XXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYT 603
+N L P V + + QI G+ H+ + + G +Y
Sbjct: 214 GLG----------------NNGNQLTPVRVAALH-SVCVNQIVCGYAHTLALTDEGLLYA 256
Query: 604 WGLNFDGQLGSGDRKQIQIPTEVKIRTE 631
WG N GQLG+G++ + P + + E
Sbjct: 257 WGANTYGQLGTGNKNNLLSPAHIMVEKE 284
Score = 66.9 bits (156), Expect = 3e-10
Identities = 60/221 (27%), Positives = 92/221 (41%), Gaps = 23/221 (10%)
Query: 412 VCVAAGHYHSAA-VDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA 470
VCV A V + +G LG G+ P+ + G+K++S+ G+
Sbjct: 24 VCVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYGS 83
Query: 471 -CHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVA---LHEPVRALAAGYFHNLAL 526
H +L T G ++A G + + QLG G + V+V L + V +A G H++AL
Sbjct: 84 GPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIATVQVCTNLLIKQVVEVACGSHHSMAL 143
Query: 527 THKGEVYVWGASP-QQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQI 585
GEV+ WG + QV P T +C+ R+V I
Sbjct: 144 AADGEVFAWGYNNCGQVGSGSTANQPTPRKVT-------------NCLHIK----RVVGI 186
Query: 586 SAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEV 626
+ G S + + G +Y WG N +GQLG G+ P V
Sbjct: 187 ACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRV 227
Score = 49.6 bits (113), Expect = 5e-05
Identities = 42/169 (24%), Positives = 72/169 (42%), Gaps = 19/169 (11%)
Query: 461 RKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV--ALHEPVRALAA 518
RKV G A ++ +T E++ G + LGTG +P ++ + +++L+
Sbjct: 22 RKVCVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSY 81
Query: 519 GYF-HNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTN 577
G H L T G VY WG + + ++ +A V T
Sbjct: 82 GSGPHVLLSTEDGVVYAWGHNGYSQLG----------------NGTTNQGIATVQVCTNL 125
Query: 578 VRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEV 626
+ ++V+++ G HHS + G ++ WG N GQ+GSG P +V
Sbjct: 126 LIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKV 174
>AL139321-5|CAH71047.1| 531|Homo sapiens regulator of chromosome
condensation (RCC1) and BTB (POZ) domain containing pro
protein.
Length = 531
Score = 101 bits (243), Expect = 1e-20
Identities = 70/216 (32%), Positives = 104/216 (48%), Gaps = 13/216 (6%)
Query: 326 WAVVSDGNARVMMASTPVNTEL-IGRVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXX 383
++ + +G +A V T L I +V++VACG HH++ L +G +++ G N GQ+
Sbjct: 104 YSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSG 163
Query: 384 XXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGL 443
+ RV V +A G S AV G + WG+ +GQLGL
Sbjct: 164 STANQPTPRKVTNCLHIKRV--------VGIACGQTSSMAVLDNGEVYGWGYNGNGQLGL 215
Query: 444 GNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASL 503
GN +Q TP V V + CG H++ LT G L+A GA+ +GQLGTG +
Sbjct: 216 GNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLS 275
Query: 504 PVRVALH-EPVRALAAGY--FHNLALTHKGEVYVWG 536
P + + E V +AA + + A T G VY+WG
Sbjct: 276 PAHIMVEKERVVEIAACHSAHTSAAKTQGGHVYMWG 311
Score = 100 bits (240), Expect = 2e-20
Identities = 65/183 (35%), Positives = 92/183 (50%), Gaps = 12/183 (6%)
Query: 360 HTLILTENGL-YSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGH 418
H L+ TE+G+ Y+ G N + QL + +V V VA G
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQV--------VEVACGS 137
Query: 419 YHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLG-RKVQSVGCGACHSVLLT 477
+HS A+ A G + WG+ GQ+G G+ +Q TP+ VT L ++V + CG S+ +
Sbjct: 138 HHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVL 197
Query: 478 RGGELWACGASVFGQLGTGQRGKASLPVRVA-LHEP-VRALAAGYFHNLALTHKGEVYVW 535
GE++ G + GQLG G G PVRVA LH V + GY H LALT +G +Y W
Sbjct: 198 DNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAW 257
Query: 536 GAS 538
GA+
Sbjct: 258 GAN 260
Score = 82.6 bits (195), Expect = 6e-15
Identities = 60/208 (28%), Positives = 94/208 (45%), Gaps = 21/208 (10%)
Query: 428 GRLLTWGWGVHGQLGLGNIDDQWTP-QLVTKFLGRKVQSVGCGACHSVLLTRGGELWACG 486
G + WG + QLG G + P Q+ T L ++V V CG+ HS+ L GE++A G
Sbjct: 94 GVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWG 153
Query: 487 ASVFGQLGTGQRGKASLPVRVA--LH-EPVRALAAGYFHNLALTHKGEVYVWGASPQQVX 543
+ GQ+G+G P +V LH + V +A G ++A+ GEVY WG +
Sbjct: 154 YNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQL 213
Query: 544 XXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYT 603
+N L P V + + QI G+ H+ + + G +Y
Sbjct: 214 GLG----------------NNGNQLTPVRVAALH-SVCVNQIVCGYAHTLALTDEGLLYA 256
Query: 604 WGLNFDGQLGSGDRKQIQIPTEVKIRTE 631
WG N GQLG+G++ + P + + E
Sbjct: 257 WGANTYGQLGTGNKNNLLSPAHIMVEKE 284
Score = 69.7 bits (163), Expect = 5e-11
Identities = 56/202 (27%), Positives = 88/202 (43%), Gaps = 22/202 (10%)
Query: 430 LLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA-CHSVLLTRGGELWACGAS 488
+ +G LG G+ P+ + G+K++S+ G+ H +L T G ++A G +
Sbjct: 43 VFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVVYAWGHN 102
Query: 489 VFGQLGTGQRGKASLPVRVA---LHEPVRALAAGYFHNLALTHKGEVYVWGASP-QQVXX 544
+ QLG G + PV+V L + V +A G H++AL GEV+ WG + QV
Sbjct: 103 GYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGS 162
Query: 545 XXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTW 604
P T +C+ R+V I+ G S + + G +Y W
Sbjct: 163 GSTANQPTPRKVT-------------NCLHIK----RVVGIACGQTSSMAVLDNGEVYGW 205
Query: 605 GLNFDGQLGSGDRKQIQIPTEV 626
G N +GQLG G+ P V
Sbjct: 206 GYNGNGQLGLGNNGNQLTPVRV 227
>AK096654-1|BAC04833.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39335 fis, clone OCBBF2017398, moderately
similar to Homo sapiens RCC1-like G exchanging factor
RLG mRNA. ).
Length = 531
Score = 101 bits (243), Expect = 1e-20
Identities = 70/216 (32%), Positives = 104/216 (48%), Gaps = 13/216 (6%)
Query: 326 WAVVSDGNARVMMASTPVNTEL-IGRVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXX 383
++ + +G +A V T L I +V++VACG HH++ L +G +++ G N GQ+
Sbjct: 104 YSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSG 163
Query: 384 XXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGL 443
+ RV V +A G S AV G + WG+ +GQLGL
Sbjct: 164 STANQPTPRKVTNCLHIKRV--------VGIACGQTSSMAVLDNGEVYGWGYNGNGQLGL 215
Query: 444 GNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASL 503
GN +Q TP V V + CG H++ LT G L+A GA+ +GQLGTG +
Sbjct: 216 GNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLS 275
Query: 504 PVRVALH-EPVRALAAGY--FHNLALTHKGEVYVWG 536
P + + E V +AA + + A T G VY+WG
Sbjct: 276 PAHIMVEKERVVEIAACHSAHTSAAKTQGGHVYMWG 311
Score = 100 bits (240), Expect = 2e-20
Identities = 65/183 (35%), Positives = 92/183 (50%), Gaps = 12/183 (6%)
Query: 360 HTLILTENGL-YSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGH 418
H L+ TE+G+ Y+ G N + QL + +V V VA G
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQV--------VEVACGS 137
Query: 419 YHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLG-RKVQSVGCGACHSVLLT 477
+HS A+ A G + WG+ GQ+G G+ +Q TP+ VT L ++V + CG S+ +
Sbjct: 138 HHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVL 197
Query: 478 RGGELWACGASVFGQLGTGQRGKASLPVRVA-LHEP-VRALAAGYFHNLALTHKGEVYVW 535
GE++ G + GQLG G G PVRVA LH V + GY H LALT +G +Y W
Sbjct: 198 DNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAW 257
Query: 536 GAS 538
GA+
Sbjct: 258 GAN 260
Score = 82.6 bits (195), Expect = 6e-15
Identities = 60/208 (28%), Positives = 94/208 (45%), Gaps = 21/208 (10%)
Query: 428 GRLLTWGWGVHGQLGLGNIDDQWTP-QLVTKFLGRKVQSVGCGACHSVLLTRGGELWACG 486
G + WG + QLG G + P Q+ T L ++V V CG+ HS+ L GE++A G
Sbjct: 94 GVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWG 153
Query: 487 ASVFGQLGTGQRGKASLPVRVA--LH-EPVRALAAGYFHNLALTHKGEVYVWGASPQQVX 543
+ GQ+G+G P +V LH + V +A G ++A+ GEVY WG +
Sbjct: 154 YNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQL 213
Query: 544 XXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYT 603
+N L P V + + QI G+ H+ + + G +Y
Sbjct: 214 GLG----------------NNGNQLTPVRVAALH-SVCVNQIVCGYAHTLALTDEGLLYA 256
Query: 604 WGLNFDGQLGSGDRKQIQIPTEVKIRTE 631
WG N GQLG+G++ + P + + E
Sbjct: 257 WGANTYGQLGTGNKNNLLSPAHIMVEKE 284
Score = 70.1 bits (164), Expect = 4e-11
Identities = 61/221 (27%), Positives = 93/221 (42%), Gaps = 23/221 (10%)
Query: 412 VCVAAGHYHSAA-VDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA 470
VCV A V + +G LG G+ P+ + G+K++S+ G+
Sbjct: 24 VCVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYGS 83
Query: 471 -CHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVA---LHEPVRALAAGYFHNLAL 526
H +L T G ++A G + + QLG G + PV+V L + V +A G H++AL
Sbjct: 84 GPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMAL 143
Query: 527 THKGEVYVWGASP-QQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQI 585
GEV+ WG + QV P T +C+ R+V I
Sbjct: 144 AADGEVFAWGYNNCGQVGSGSTANQPTPRKVT-------------NCLHIK----RVVGI 186
Query: 586 SAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEV 626
+ G S + + G +Y WG N +GQLG G+ P V
Sbjct: 187 ACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRV 227
Score = 52.8 bits (121), Expect = 6e-06
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 19/169 (11%)
Query: 461 RKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV--ALHEPVRALAA 518
RKV G A ++ +T E++ G + LGTG +P ++ + +++L+
Sbjct: 22 RKVCVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSY 81
Query: 519 GYF-HNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTN 577
G H L T G VY WG + + ++ +AP V T
Sbjct: 82 GSGPHVLLSTEDGVVYAWGHNGYSQLG----------------NGTTNQGIAPVQVCTNL 125
Query: 578 VRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEV 626
+ ++V+++ G HHS + G ++ WG N GQ+GSG P +V
Sbjct: 126 LIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKV 174
>AJ319660-1|CAC40027.1| 531|Homo sapiens guanine nucleotide
exchange factor protein.
Length = 531
Score = 101 bits (243), Expect = 1e-20
Identities = 70/216 (32%), Positives = 104/216 (48%), Gaps = 13/216 (6%)
Query: 326 WAVVSDGNARVMMASTPVNTEL-IGRVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXX 383
++ + +G +A V T L I +V++VACG HH++ L +G +++ G N GQ+
Sbjct: 104 YSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSG 163
Query: 384 XXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGL 443
+ RV V +A G S AV G + WG+ +GQLGL
Sbjct: 164 STANQPTPRKVTNCLHIKRV--------VGIACGQTSSMAVLDNGEVYGWGYNGNGQLGL 215
Query: 444 GNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASL 503
GN +Q TP V V + CG H++ LT G L+A GA+ +GQLGTG +
Sbjct: 216 GNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLS 275
Query: 504 PVRVALH-EPVRALAAGY--FHNLALTHKGEVYVWG 536
P + + E V +AA + + A T G VY+WG
Sbjct: 276 PAHIMVEKERVVEIAACHSAHTSAAKTQGGHVYMWG 311
Score = 100 bits (240), Expect = 2e-20
Identities = 65/183 (35%), Positives = 92/183 (50%), Gaps = 12/183 (6%)
Query: 360 HTLILTENGL-YSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGH 418
H L+ TE+G+ Y+ G N + QL + +V V VA G
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQV--------VEVACGS 137
Query: 419 YHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLG-RKVQSVGCGACHSVLLT 477
+HS A+ A G + WG+ GQ+G G+ +Q TP+ VT L ++V + CG S+ +
Sbjct: 138 HHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVL 197
Query: 478 RGGELWACGASVFGQLGTGQRGKASLPVRVA-LHEP-VRALAAGYFHNLALTHKGEVYVW 535
GE++ G + GQLG G G PVRVA LH V + GY H LALT +G +Y W
Sbjct: 198 DNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAW 257
Query: 536 GAS 538
GA+
Sbjct: 258 GAN 260
Score = 82.6 bits (195), Expect = 6e-15
Identities = 60/208 (28%), Positives = 94/208 (45%), Gaps = 21/208 (10%)
Query: 428 GRLLTWGWGVHGQLGLGNIDDQWTP-QLVTKFLGRKVQSVGCGACHSVLLTRGGELWACG 486
G + WG + QLG G + P Q+ T L ++V V CG+ HS+ L GE++A G
Sbjct: 94 GVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWG 153
Query: 487 ASVFGQLGTGQRGKASLPVRVA--LH-EPVRALAAGYFHNLALTHKGEVYVWGASPQQVX 543
+ GQ+G+G P +V LH + V +A G ++A+ GEVY WG +
Sbjct: 154 YNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQL 213
Query: 544 XXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYT 603
+N L P V + + QI G+ H+ + + G +Y
Sbjct: 214 GLG----------------NNGNQLTPVRVAALH-SVCVNQIVCGYAHTLALTDEGLLYA 256
Query: 604 WGLNFDGQLGSGDRKQIQIPTEVKIRTE 631
WG N GQLG+G++ + P + + E
Sbjct: 257 WGANTYGQLGTGNKNNLLSPAHIMVEKE 284
Score = 70.1 bits (164), Expect = 4e-11
Identities = 61/221 (27%), Positives = 93/221 (42%), Gaps = 23/221 (10%)
Query: 412 VCVAAGHYHSAA-VDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA 470
VCV A V + +G LG G+ P+ + G+K++S+ G+
Sbjct: 24 VCVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYGS 83
Query: 471 -CHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVA---LHEPVRALAAGYFHNLAL 526
H +L T G ++A G + + QLG G + PV+V L + V +A G H++AL
Sbjct: 84 GPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMAL 143
Query: 527 THKGEVYVWGASP-QQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQI 585
GEV+ WG + QV P T +C+ R+V I
Sbjct: 144 AADGEVFAWGYNNCGQVGSGSTANQPTPRKVT-------------NCLHIK----RVVGI 186
Query: 586 SAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEV 626
+ G S + + G +Y WG N +GQLG G+ P V
Sbjct: 187 ACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRV 227
Score = 52.8 bits (121), Expect = 6e-06
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 19/169 (11%)
Query: 461 RKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV--ALHEPVRALAA 518
RKV G A ++ +T E++ G + LGTG +P ++ + +++L+
Sbjct: 22 RKVCVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSY 81
Query: 519 GYF-HNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTN 577
G H L T G VY WG + + ++ +AP V T
Sbjct: 82 GSGPHVLLSTEDGVVYAWGHNGYSQLG----------------NGTTNQGIAPVQVCTNL 125
Query: 578 VRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEV 626
+ ++V+++ G HHS + G ++ WG N GQ+GSG P +V
Sbjct: 126 LIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKV 174
>AF334406-1|AAK38372.1| 531|Homo sapiens CLLL7 protein protein.
Length = 531
Score = 101 bits (243), Expect = 1e-20
Identities = 70/216 (32%), Positives = 104/216 (48%), Gaps = 13/216 (6%)
Query: 326 WAVVSDGNARVMMASTPVNTEL-IGRVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXX 383
++ + +G +A V T L I +V++VACG HH++ L +G +++ G N GQ+
Sbjct: 104 YSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSG 163
Query: 384 XXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGL 443
+ RV V +A G S AV G + WG+ +GQLGL
Sbjct: 164 STANQPTPRKVTNCLHIKRV--------VGIACGQTSSMAVLDNGEVYGWGYNGNGQLGL 215
Query: 444 GNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASL 503
GN +Q TP V V + CG H++ LT G L+A GA+ +GQLGTG +
Sbjct: 216 GNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLS 275
Query: 504 PVRVALH-EPVRALAAGY--FHNLALTHKGEVYVWG 536
P + + E V +AA + + A T G VY+WG
Sbjct: 276 PAHIMVEKERVVEIAACHSAHTSAAKTQGGHVYMWG 311
Score = 100 bits (240), Expect = 2e-20
Identities = 65/183 (35%), Positives = 92/183 (50%), Gaps = 12/183 (6%)
Query: 360 HTLILTENGL-YSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGH 418
H L+ TE+G+ Y+ G N + QL + +V V VA G
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQV--------VEVACGS 137
Query: 419 YHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLG-RKVQSVGCGACHSVLLT 477
+HS A+ A G + WG+ GQ+G G+ +Q TP+ VT L ++V + CG S+ +
Sbjct: 138 HHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVL 197
Query: 478 RGGELWACGASVFGQLGTGQRGKASLPVRVA-LHEP-VRALAAGYFHNLALTHKGEVYVW 535
GE++ G + GQLG G G PVRVA LH V + GY H LALT +G +Y W
Sbjct: 198 DNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAW 257
Query: 536 GAS 538
GA+
Sbjct: 258 GAN 260
Score = 82.6 bits (195), Expect = 6e-15
Identities = 60/208 (28%), Positives = 94/208 (45%), Gaps = 21/208 (10%)
Query: 428 GRLLTWGWGVHGQLGLGNIDDQWTP-QLVTKFLGRKVQSVGCGACHSVLLTRGGELWACG 486
G + WG + QLG G + P Q+ T L ++V V CG+ HS+ L GE++A G
Sbjct: 94 GVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWG 153
Query: 487 ASVFGQLGTGQRGKASLPVRVA--LH-EPVRALAAGYFHNLALTHKGEVYVWGASPQQVX 543
+ GQ+G+G P +V LH + V +A G ++A+ GEVY WG +
Sbjct: 154 YNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQL 213
Query: 544 XXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYT 603
+N L P V + + QI G+ H+ + + G +Y
Sbjct: 214 GLG----------------NNGNQLTPVRVAALH-SVCVNQIVCGYAHTLALTDEGLLYA 256
Query: 604 WGLNFDGQLGSGDRKQIQIPTEVKIRTE 631
WG N GQLG+G++ + P + + E
Sbjct: 257 WGANTYGQLGTGNKNNLLSPAHIMVEKE 284
Score = 70.1 bits (164), Expect = 4e-11
Identities = 61/221 (27%), Positives = 93/221 (42%), Gaps = 23/221 (10%)
Query: 412 VCVAAGHYHSAA-VDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA 470
VCV A V + +G LG G+ P+ + G+K++S+ G+
Sbjct: 24 VCVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYGS 83
Query: 471 -CHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVA---LHEPVRALAAGYFHNLAL 526
H +L T G ++A G + + QLG G + PV+V L + V +A G H++AL
Sbjct: 84 GPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMAL 143
Query: 527 THKGEVYVWGASP-QQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQI 585
GEV+ WG + QV P T +C+ R+V I
Sbjct: 144 AADGEVFAWGYNNCGQVGSGSTANQPTPRKVT-------------NCLHIK----RVVGI 186
Query: 586 SAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEV 626
+ G S + + G +Y WG N +GQLG G+ P V
Sbjct: 187 ACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRV 227
Score = 52.8 bits (121), Expect = 6e-06
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 19/169 (11%)
Query: 461 RKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV--ALHEPVRALAA 518
RKV G A ++ +T E++ G + LGTG +P ++ + +++L+
Sbjct: 22 RKVCVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSY 81
Query: 519 GYF-HNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTN 577
G H L T G VY WG + + ++ +AP V T
Sbjct: 82 GSGPHVLLSTEDGVVYAWGHNGYSQLG----------------NGTTNQGIAPVQVCTNL 125
Query: 578 VRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEV 626
+ ++V+++ G HHS + G ++ WG N GQ+GSG P +V
Sbjct: 126 LIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKV 174
>BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 101 bits (242), Expect = 1e-20
Identities = 81/283 (28%), Positives = 123/283 (43%), Gaps = 32/283 (11%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
++ V+CG HTL L + G +Y+ G ++ GQL ++
Sbjct: 86 IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPR--------NIKSLSDI 137
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLGRKVQSVGC 468
+V VA G+YHS A+ + WG +GQLGLG + Q +PQL+ LG V
Sbjct: 138 QIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAA 197
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLAL 526
G HS +LT G ++ G + FGQLG +P ++ + + + G H AL
Sbjct: 198 GGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAAL 257
Query: 527 THKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIV-QI 585
T +G V+ +GA H+ N R + G IV +I
Sbjct: 258 TKEGGVFTFGAGGYGQLGHNSTS-----------HEINPR-------KVFELMGSIVTEI 299
Query: 586 SAGWHH-SCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
+ G H S + + G IY++GL +GQLG+G + P VK
Sbjct: 300 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVK 342
Score = 92.3 bits (219), Expect = 8e-18
Identities = 62/201 (30%), Positives = 96/201 (47%), Gaps = 19/201 (9%)
Query: 430 LLTWGWGVHGQLGLGNIDDQWT--PQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGA 487
+L WG GQLGLG ID++ P+ F+ ++V+ VGCG H+V + G ++ CG
Sbjct: 1 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC 60
Query: 488 SVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXX 547
+ GQLG + K V + + A++ G H LAL KG+VY WG
Sbjct: 61 NDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLD--------- 111
Query: 548 XXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLN 607
S L + P + + + +IVQ++ G++HS ++ ++ WG N
Sbjct: 112 ------SDGQLGLVGSEECIRVPRNIKSLS-DIQIVQVACGYYHSLALSKASEVFCWGQN 164
Query: 608 FDGQLGSG-DRKQIQIPTEVK 627
GQLG G D K+ P +K
Sbjct: 165 KYGQLGLGTDCKKQTSPQLLK 185
Score = 72.1 bits (169), Expect = 9e-12
Identities = 58/217 (26%), Positives = 95/217 (43%), Gaps = 21/217 (9%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHS 473
V G H+ V G + T G GQLG + + P+ V + + +V CG H+
Sbjct: 39 VGCGLRHTVFVLDDGTVYTCGCNDLGQLG--HEKSRKKPEQVVALDAQNIVAVSCGEAHT 96
Query: 474 VLLTRGGELWACGASVFGQLG-TGQRGKASLPVRVALHEPVR--ALAAGYFHNLALTHKG 530
+ L G+++A G GQLG G +P + ++ +A GY+H+LAL+
Sbjct: 97 LALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKAS 156
Query: 531 EVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWH 590
EV+ WG + L D + +P + + + +Q++AG
Sbjct: 157 EVFCWG---------------QNKYGQLGLGTDCKKQTSPQLLKSL-LGIPFMQVAAGGA 200
Query: 591 HSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
HS ++ G+I+ WG N GQLG D +P +K
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLK 237
Score = 48.0 bits (109), Expect = 2e-04
Identities = 21/53 (39%), Positives = 33/53 (62%), Gaps = 1/53 (1%)
Query: 582 IVQISAGWHHSCIINNMGSIYTWGLNFDGQLG-SGDRKQIQIPTEVKIRTETQ 633
IV +S G H+ +N+ G +Y WGL+ DGQLG G + I++P +K ++ Q
Sbjct: 86 IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQ 138
Score = 44.0 bits (99), Expect = 0.003
Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 11/105 (10%)
Query: 350 RVIDVACGRHHTLILT-ENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
+++ + CG HT LT E G+++ G +GQL +V G
Sbjct: 243 KIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPR---------KVFELMG 293
Query: 409 APLVCVAAGHYH-SAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP 452
+ + +A G H SA V + GR+ ++G G +GQLG G+ ++ +P
Sbjct: 294 SIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSP 338
Score = 33.5 bits (73), Expect = 3.8
Identities = 15/51 (29%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 659 VGCGGDFTVYIDDDGRIYSTGNTHL-QISNEKTKGGNRVIMMKTTKRVIKI 708
VGCG TV++ DDG +Y+ G L Q+ +EK++ ++ + ++ +
Sbjct: 39 VGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDAQNIVAV 89
>AY650033-1|AAV66579.1| 979|Homo sapiens HECT and RCC1 containing
protein 4 isoform 3 protein.
Length = 979
Score = 101 bits (242), Expect = 1e-20
Identities = 81/283 (28%), Positives = 123/283 (43%), Gaps = 32/283 (11%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
++ V+CG HTL L + G +Y+ G ++ GQL ++
Sbjct: 86 IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPR--------NIKSLSDI 137
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLGRKVQSVGC 468
+V VA G+YHS A+ + WG +GQLGLG + Q +PQL+ LG V
Sbjct: 138 QIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAA 197
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLAL 526
G HS +LT G ++ G + FGQLG +P ++ + + + G H AL
Sbjct: 198 GGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAAL 257
Query: 527 THKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIV-QI 585
T +G V+ +GA H+ N R + G IV +I
Sbjct: 258 TKEGGVFTFGAGGYGQLGHNSTS-----------HEINPR-------KVFELMGSIVTEI 299
Query: 586 SAGWHH-SCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
+ G H S + + G IY++GL +GQLG+G + P VK
Sbjct: 300 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVK 342
Score = 92.3 bits (219), Expect = 8e-18
Identities = 62/201 (30%), Positives = 96/201 (47%), Gaps = 19/201 (9%)
Query: 430 LLTWGWGVHGQLGLGNIDDQWT--PQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGA 487
+L WG GQLGLG ID++ P+ F+ ++V+ VGCG H+V + G ++ CG
Sbjct: 1 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC 60
Query: 488 SVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXX 547
+ GQLG + K V + + A++ G H LAL KG+VY WG
Sbjct: 61 NDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLD--------- 111
Query: 548 XXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLN 607
S L + P + + + +IVQ++ G++HS ++ ++ WG N
Sbjct: 112 ------SDGQLGLVGSEECIRVPRNIKSLS-DIQIVQVACGYYHSLALSKASEVFCWGQN 164
Query: 608 FDGQLGSG-DRKQIQIPTEVK 627
GQLG G D K+ P +K
Sbjct: 165 KYGQLGLGTDCKKQTSPQLLK 185
Score = 72.1 bits (169), Expect = 9e-12
Identities = 58/217 (26%), Positives = 95/217 (43%), Gaps = 21/217 (9%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHS 473
V G H+ V G + T G GQLG + + P+ V + + +V CG H+
Sbjct: 39 VGCGLRHTVFVLDDGTVYTCGCNDLGQLG--HEKSRKKPEQVVALDAQNIVAVSCGEAHT 96
Query: 474 VLLTRGGELWACGASVFGQLG-TGQRGKASLPVRVALHEPVR--ALAAGYFHNLALTHKG 530
+ L G+++A G GQLG G +P + ++ +A GY+H+LAL+
Sbjct: 97 LALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKAS 156
Query: 531 EVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWH 590
EV+ WG + L D + +P + + + +Q++AG
Sbjct: 157 EVFCWG---------------QNKYGQLGLGTDCKKQTSPQLLKSL-LGIPFMQVAAGGA 200
Query: 591 HSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
HS ++ G+I+ WG N GQLG D +P +K
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLK 237
Score = 48.0 bits (109), Expect = 2e-04
Identities = 21/53 (39%), Positives = 33/53 (62%), Gaps = 1/53 (1%)
Query: 582 IVQISAGWHHSCIINNMGSIYTWGLNFDGQLG-SGDRKQIQIPTEVKIRTETQ 633
IV +S G H+ +N+ G +Y WGL+ DGQLG G + I++P +K ++ Q
Sbjct: 86 IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQ 138
Score = 44.0 bits (99), Expect = 0.003
Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 11/105 (10%)
Query: 350 RVIDVACGRHHTLILT-ENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
+++ + CG HT LT E G+++ G +GQL +V G
Sbjct: 243 KIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPR---------KVFELMG 293
Query: 409 APLVCVAAGHYH-SAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP 452
+ + +A G H SA V + GR+ ++G G +GQLG G+ ++ +P
Sbjct: 294 SIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSP 338
Score = 33.5 bits (73), Expect = 3.8
Identities = 15/51 (29%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 659 VGCGGDFTVYIDDDGRIYSTGNTHL-QISNEKTKGGNRVIMMKTTKRVIKI 708
VGCG TV++ DDG +Y+ G L Q+ +EK++ ++ + ++ +
Sbjct: 39 VGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDAQNIVAV 89
>AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containing
protein 4 isoform 1 protein.
Length = 1057
Score = 101 bits (242), Expect = 1e-20
Identities = 81/283 (28%), Positives = 123/283 (43%), Gaps = 32/283 (11%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
++ V+CG HTL L + G +Y+ G ++ GQL ++
Sbjct: 86 IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPR--------NIKSLSDI 137
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLGRKVQSVGC 468
+V VA G+YHS A+ + WG +GQLGLG + Q +PQL+ LG V
Sbjct: 138 QIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAA 197
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLAL 526
G HS +LT G ++ G + FGQLG +P ++ + + + G H AL
Sbjct: 198 GGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAAL 257
Query: 527 THKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIV-QI 585
T +G V+ +GA H+ N R + G IV +I
Sbjct: 258 TKEGGVFTFGAGGYGQLGHNSTS-----------HEINPR-------KVFELMGSIVTEI 299
Query: 586 SAGWHH-SCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
+ G H S + + G IY++GL +GQLG+G + P VK
Sbjct: 300 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVK 342
Score = 92.3 bits (219), Expect = 8e-18
Identities = 62/201 (30%), Positives = 96/201 (47%), Gaps = 19/201 (9%)
Query: 430 LLTWGWGVHGQLGLGNIDDQWT--PQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGA 487
+L WG GQLGLG ID++ P+ F+ ++V+ VGCG H+V + G ++ CG
Sbjct: 1 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC 60
Query: 488 SVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXX 547
+ GQLG + K V + + A++ G H LAL KG+VY WG
Sbjct: 61 NDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLD--------- 111
Query: 548 XXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLN 607
S L + P + + + +IVQ++ G++HS ++ ++ WG N
Sbjct: 112 ------SDGQLGLVGSEECIRVPRNIKSLS-DIQIVQVACGYYHSLALSKASEVFCWGQN 164
Query: 608 FDGQLGSG-DRKQIQIPTEVK 627
GQLG G D K+ P +K
Sbjct: 165 KYGQLGLGTDCKKQTSPQLLK 185
Score = 72.1 bits (169), Expect = 9e-12
Identities = 58/217 (26%), Positives = 95/217 (43%), Gaps = 21/217 (9%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHS 473
V G H+ V G + T G GQLG + + P+ V + + +V CG H+
Sbjct: 39 VGCGLRHTVFVLDDGTVYTCGCNDLGQLG--HEKSRKKPEQVVALDAQNIVAVSCGEAHT 96
Query: 474 VLLTRGGELWACGASVFGQLG-TGQRGKASLPVRVALHEPVR--ALAAGYFHNLALTHKG 530
+ L G+++A G GQLG G +P + ++ +A GY+H+LAL+
Sbjct: 97 LALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKAS 156
Query: 531 EVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWH 590
EV+ WG + L D + +P + + + +Q++AG
Sbjct: 157 EVFCWG---------------QNKYGQLGLGTDCKKQTSPQLLKSL-LGIPFMQVAAGGA 200
Query: 591 HSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
HS ++ G+I+ WG N GQLG D +P +K
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLK 237
Score = 48.0 bits (109), Expect = 2e-04
Identities = 21/53 (39%), Positives = 33/53 (62%), Gaps = 1/53 (1%)
Query: 582 IVQISAGWHHSCIINNMGSIYTWGLNFDGQLG-SGDRKQIQIPTEVKIRTETQ 633
IV +S G H+ +N+ G +Y WGL+ DGQLG G + I++P +K ++ Q
Sbjct: 86 IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQ 138
Score = 44.0 bits (99), Expect = 0.003
Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 11/105 (10%)
Query: 350 RVIDVACGRHHTLILT-ENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
+++ + CG HT LT E G+++ G +GQL +V G
Sbjct: 243 KIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPR---------KVFELMG 293
Query: 409 APLVCVAAGHYH-SAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP 452
+ + +A G H SA V + GR+ ++G G +GQLG G+ ++ +P
Sbjct: 294 SIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSP 338
Score = 33.5 bits (73), Expect = 3.8
Identities = 15/51 (29%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 659 VGCGGDFTVYIDDDGRIYSTGNTHL-QISNEKTKGGNRVIMMKTTKRVIKI 708
VGCG TV++ DDG +Y+ G L Q+ +EK++ ++ + ++ +
Sbjct: 39 VGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDAQNIVAV 89
>AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 101 bits (242), Expect = 1e-20
Identities = 81/283 (28%), Positives = 123/283 (43%), Gaps = 32/283 (11%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
++ V+CG HTL L + G +Y+ G ++ GQL ++
Sbjct: 86 IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPR--------NIKSLSDI 137
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLGRKVQSVGC 468
+V VA G+YHS A+ + WG +GQLGLG + Q +PQL+ LG V
Sbjct: 138 QIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAA 197
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLAL 526
G HS +LT G ++ G + FGQLG +P ++ + + + G H AL
Sbjct: 198 GGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAAL 257
Query: 527 THKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIV-QI 585
T +G V+ +GA H+ N R + G IV +I
Sbjct: 258 TKEGGVFTFGAGGYGQLGHNSTS-----------HEINPR-------KVFELMGSIVTEI 299
Query: 586 SAGWHH-SCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
+ G H S + + G IY++GL +GQLG+G + P VK
Sbjct: 300 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVK 342
Score = 92.3 bits (219), Expect = 8e-18
Identities = 62/201 (30%), Positives = 96/201 (47%), Gaps = 19/201 (9%)
Query: 430 LLTWGWGVHGQLGLGNIDDQWT--PQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGA 487
+L WG GQLGLG ID++ P+ F+ ++V+ VGCG H+V + G ++ CG
Sbjct: 1 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC 60
Query: 488 SVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXX 547
+ GQLG + K V + + A++ G H LAL KG+VY WG
Sbjct: 61 NDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLD--------- 111
Query: 548 XXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLN 607
S L + P + + + +IVQ++ G++HS ++ ++ WG N
Sbjct: 112 ------SDGQLGLVGSEECIRVPRNIKSLS-DIQIVQVACGYYHSLALSKASEVFCWGQN 164
Query: 608 FDGQLGSG-DRKQIQIPTEVK 627
GQLG G D K+ P +K
Sbjct: 165 KYGQLGLGTDCKKQTSPQLLK 185
Score = 72.1 bits (169), Expect = 9e-12
Identities = 58/217 (26%), Positives = 95/217 (43%), Gaps = 21/217 (9%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHS 473
V G H+ V G + T G GQLG + + P+ V + + +V CG H+
Sbjct: 39 VGCGLRHTVFVLDDGTVYTCGCNDLGQLG--HEKSRKKPEQVVALDAQNIVAVSCGEAHT 96
Query: 474 VLLTRGGELWACGASVFGQLG-TGQRGKASLPVRVALHEPVR--ALAAGYFHNLALTHKG 530
+ L G+++A G GQLG G +P + ++ +A GY+H+LAL+
Sbjct: 97 LALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKAS 156
Query: 531 EVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWH 590
EV+ WG + L D + +P + + + +Q++AG
Sbjct: 157 EVFCWG---------------QNKYGQLGLGTDCKKQTSPQLLKSL-LGIPFMQVAAGGA 200
Query: 591 HSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
HS ++ G+I+ WG N GQLG D +P +K
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLK 237
Score = 48.0 bits (109), Expect = 2e-04
Identities = 21/53 (39%), Positives = 33/53 (62%), Gaps = 1/53 (1%)
Query: 582 IVQISAGWHHSCIINNMGSIYTWGLNFDGQLG-SGDRKQIQIPTEVKIRTETQ 633
IV +S G H+ +N+ G +Y WGL+ DGQLG G + I++P +K ++ Q
Sbjct: 86 IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQ 138
Score = 44.0 bits (99), Expect = 0.003
Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 11/105 (10%)
Query: 350 RVIDVACGRHHTLILT-ENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
+++ + CG HT LT E G+++ G +GQL +V G
Sbjct: 243 KIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPR---------KVFELMG 293
Query: 409 APLVCVAAGHYH-SAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP 452
+ + +A G H SA V + GR+ ++G G +GQLG G+ ++ +P
Sbjct: 294 SIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSP 338
Score = 33.5 bits (73), Expect = 3.8
Identities = 15/51 (29%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 659 VGCGGDFTVYIDDDGRIYSTGNTHL-QISNEKTKGGNRVIMMKTTKRVIKI 708
VGCG TV++ DDG +Y+ G L Q+ +EK++ ++ + ++ +
Sbjct: 39 VGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDAQNIVAV 89
>AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 101 bits (242), Expect = 1e-20
Identities = 81/283 (28%), Positives = 123/283 (43%), Gaps = 32/283 (11%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
++ V+CG HTL L + G +Y+ G ++ GQL ++
Sbjct: 86 IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPR--------NIKSLSDI 137
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLGRKVQSVGC 468
+V VA G+YHS A+ + WG +GQLGLG + Q +PQL+ LG V
Sbjct: 138 QIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAA 197
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLAL 526
G HS +LT G ++ G + FGQLG +P ++ + + + G H AL
Sbjct: 198 GGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAAL 257
Query: 527 THKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIV-QI 585
T +G V+ +GA H+ N R + G IV +I
Sbjct: 258 TKEGGVFTFGAGGYGQLGHNSTS-----------HEINPR-------KVFELMGSIVTEI 299
Query: 586 SAGWHH-SCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
+ G H S + + G IY++GL +GQLG+G + P VK
Sbjct: 300 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVK 342
Score = 92.3 bits (219), Expect = 8e-18
Identities = 62/201 (30%), Positives = 96/201 (47%), Gaps = 19/201 (9%)
Query: 430 LLTWGWGVHGQLGLGNIDDQWT--PQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGA 487
+L WG GQLGLG ID++ P+ F+ ++V+ VGCG H+V + G ++ CG
Sbjct: 1 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC 60
Query: 488 SVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXX 547
+ GQLG + K V + + A++ G H LAL KG+VY WG
Sbjct: 61 NDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLD--------- 111
Query: 548 XXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLN 607
S L + P + + + +IVQ++ G++HS ++ ++ WG N
Sbjct: 112 ------SDGQLGLVGSEECIRVPRNIKSLS-DIQIVQVACGYYHSLALSKASEVFCWGQN 164
Query: 608 FDGQLGSG-DRKQIQIPTEVK 627
GQLG G D K+ P +K
Sbjct: 165 KYGQLGLGTDCKKQTSPQLLK 185
Score = 72.1 bits (169), Expect = 9e-12
Identities = 58/217 (26%), Positives = 95/217 (43%), Gaps = 21/217 (9%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHS 473
V G H+ V G + T G GQLG + + P+ V + + +V CG H+
Sbjct: 39 VGCGLRHTVFVLDDGTVYTCGCNDLGQLG--HEKSRKKPEQVVALDAQNIVAVSCGEAHT 96
Query: 474 VLLTRGGELWACGASVFGQLG-TGQRGKASLPVRVALHEPVR--ALAAGYFHNLALTHKG 530
+ L G+++A G GQLG G +P + ++ +A GY+H+LAL+
Sbjct: 97 LALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKAS 156
Query: 531 EVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWH 590
EV+ WG + L D + +P + + + +Q++AG
Sbjct: 157 EVFCWG---------------QNKYGQLGLGTDCKKQTSPQLLKSL-LGIPFMQVAAGGA 200
Query: 591 HSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
HS ++ G+I+ WG N GQLG D +P +K
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLK 237
Score = 48.0 bits (109), Expect = 2e-04
Identities = 21/53 (39%), Positives = 33/53 (62%), Gaps = 1/53 (1%)
Query: 582 IVQISAGWHHSCIINNMGSIYTWGLNFDGQLG-SGDRKQIQIPTEVKIRTETQ 633
IV +S G H+ +N+ G +Y WGL+ DGQLG G + I++P +K ++ Q
Sbjct: 86 IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQ 138
Score = 44.0 bits (99), Expect = 0.003
Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 11/105 (10%)
Query: 350 RVIDVACGRHHTLILT-ENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
+++ + CG HT LT E G+++ G +GQL +V G
Sbjct: 243 KIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPR---------KVFELMG 293
Query: 409 APLVCVAAGHYH-SAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP 452
+ + +A G H SA V + GR+ ++G G +GQLG G+ ++ +P
Sbjct: 294 SIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSP 338
Score = 33.5 bits (73), Expect = 3.8
Identities = 15/51 (29%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 659 VGCGGDFTVYIDDDGRIYSTGNTHL-QISNEKTKGGNRVIMMKTTKRVIKI 708
VGCG TV++ DDG +Y+ G L Q+ +EK++ ++ + ++ +
Sbjct: 39 VGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDAQNIVAV 89
>AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein.
Length = 4834
Score = 101 bits (242), Expect = 1e-20
Identities = 69/220 (31%), Positives = 99/220 (45%), Gaps = 21/220 (9%)
Query: 408 GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVG 467
G +V VAAG HSA V A G L TWG G +G+LG + +DQ P+LV G +V +
Sbjct: 4090 GIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIA 4149
Query: 468 CGA--CHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV--ALHEPVRALAAGYFHN 523
CG+ ++ LT +W+ G +G+LG G +P+++ V + G +
Sbjct: 4150 CGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFS 4209
Query: 524 LALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIV 583
+ALT G VY WG H +D P V + +++
Sbjct: 4210 VALTKSGAVYTWGKGDYHRLG----------------HGSDDHVRRPRQVQGLQGK-KVI 4252
Query: 584 QISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIP 623
I+ G H G +YTWG N +GQLG G IQ P
Sbjct: 4253 AIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRP 4292
Score = 93.1 bits (221), Expect = 4e-18
Identities = 80/304 (26%), Positives = 131/304 (43%), Gaps = 32/304 (10%)
Query: 329 VSDGNARVMMASTPVNTELIGRVIDVACGRHHTLILTENGLYSAGDNTFGQLXXXXXXXX 388
+S G + T +++ ++ +V + GRH T + + ++S G+ G+L
Sbjct: 3028 ISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNC 3087
Query: 389 XXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDD 448
R+R +A G HSAA+ + G L TWG G +G+LG G+
Sbjct: 3088 DKPRLIEALKTK-RIR--------DIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTT 3138
Query: 449 QWTPQLVTKFLGRKVQSVGCGA--CHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVR 506
Q P++V LG +V V CG+ ++ LT G +++ G FG+LG G ++P
Sbjct: 3139 QLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQN 3198
Query: 507 VAL--HEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDN 564
+ + V + G +LALT G V+ WG H +
Sbjct: 3199 IERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLG----------------HGSD 3242
Query: 565 DRYLAPSCVDTTNVRGR-IVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIP 623
P V+ +RG+ IV ++ G H + + G +Y WG N GQ G+G + P
Sbjct: 3243 VHVRKPQVVE--GLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKP 3300
Query: 624 TEVK 627
T V+
Sbjct: 3301 TLVQ 3304
Score = 85.8 bits (203), Expect = 7e-16
Identities = 48/138 (34%), Positives = 72/138 (52%), Gaps = 4/138 (2%)
Query: 408 GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVG 467
G +V +A G +SAA+ A G L TWG G +G+LG G+ +D+ P LV G KV V
Sbjct: 550 GKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVA 609
Query: 468 CGA--CHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHE--PVRALAAGYFHN 523
CG+ ++ +T G++W+ G +G+LG G P + + V + G +
Sbjct: 610 CGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVKVRCGSQFS 669
Query: 524 LALTHKGEVYVWGASPQQ 541
+ALT G+VY WG Q
Sbjct: 670 IALTKDGQVYSWGKGDNQ 687
Score = 80.2 bits (189), Expect = 3e-14
Identities = 56/193 (29%), Positives = 90/193 (46%), Gaps = 10/193 (5%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
V+ +ACG ++ +T G LY+ G +G+L + + +A G+
Sbjct: 553 VVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGS 612
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCG 469
G + AV G++ +WG G +G+LG G D TP+L+ K V V CG
Sbjct: 613 -------GDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVKVRCG 665
Query: 470 ACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLALT 527
+ S+ LT+ G++++ G +LG G P + + V +AAG H LALT
Sbjct: 666 SQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALT 725
Query: 528 HKGEVYVWGASPQ 540
EV+ WG++ Q
Sbjct: 726 EDSEVHSWGSNDQ 738
Score = 76.6 bits (180), Expect = 4e-13
Identities = 72/282 (25%), Positives = 115/282 (40%), Gaps = 28/282 (9%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
V+ VA G +T G +Y+ G+ T G+L V+
Sbjct: 2994 VVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLGISSGTVPIPRQITALSSYVVKK---- 3049
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCG 469
V V +G H+ A+ G++ +WG G G+LG + + P+L+ ++++ + CG
Sbjct: 3050 --VAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACG 3107
Query: 470 ACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGY--FHNLA 525
+ HS LT GEL+ G +G+LG G P V+V L V +A G LA
Sbjct: 3108 SSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLA 3167
Query: 526 LTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQI 585
LT +G V+ WG E + P ++ N +G + QI
Sbjct: 3168 LTDEGLVFSWGDGD---FGKLGRGGSEGCN-------------IPQNIERLNGQG-VCQI 3210
Query: 586 SAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
G S + G ++TWG +LG G ++ P V+
Sbjct: 3211 ECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVE 3252
Score = 72.5 bits (170), Expect = 7e-12
Identities = 56/181 (30%), Positives = 83/181 (45%), Gaps = 14/181 (7%)
Query: 350 RVIDVACGRH--HTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLA 406
RV+D+ACG TL LT++ ++S GD +G+L +++
Sbjct: 4144 RVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVP---------MKIDSL 4194
Query: 407 GGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSV 466
G +V V G S A+ G + TWG G + +LG G+ D P+ V G+KV ++
Sbjct: 4195 TGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAI 4254
Query: 467 GCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVAL--HEPVRALAAGYFHNL 524
G+ H V T GE++ G + GQLG G P VA + V +A G H L
Sbjct: 4255 ATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTL 4314
Query: 525 A 525
A
Sbjct: 4315 A 4315
Score = 71.7 bits (168), Expect = 1e-11
Identities = 54/215 (25%), Positives = 96/215 (44%), Gaps = 26/215 (12%)
Query: 417 GHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRK----VQSVGCGACH 472
GH H A+ A G + +WG G G+LG G+ P++++ F G++ V + CG+ +
Sbjct: 504 GH-HYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTY 562
Query: 473 SVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPVR----ALAAGYFHNLALTH 528
S +T GEL+ G +G+LG G ++P+ VA + ++ A +G LA+T
Sbjct: 563 SAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTE 622
Query: 529 KGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAG 588
G+V+ WG +D P ++ +V++ G
Sbjct: 623 NGQVWSWGDGDYGKLG----------------RGGSDGCKTPKLIEKLQDLD-VVKVRCG 665
Query: 589 WHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIP 623
S + G +Y+WG + +LG G + ++ P
Sbjct: 666 SQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYP 700
Score = 71.7 bits (168), Expect = 1e-11
Identities = 64/213 (30%), Positives = 93/213 (43%), Gaps = 14/213 (6%)
Query: 320 TCGLAHWAVVSDGNARVMMASTPVNTELIGRVIDVACGRH--HTLILTENGL-YSAGDNT 376
T GL + + G+ + V L RVI VACG TL LT+ GL +S GD
Sbjct: 3122 TWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGD 3181
Query: 377 FGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWG 436
FG+L + R+ G + C G S A+ G + TWG G
Sbjct: 3182 FGKLGRGGSEGCNIPQN------IERLNGQGVCQIEC---GAQFSLALTKSGVVWTWGKG 3232
Query: 437 VHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTG 496
+ +LG G+ PQ+V G+K+ V GA H + +T G+++A G + GQ G G
Sbjct: 3233 DYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNG 3292
Query: 497 QRGKASLPVRV-ALH-EPVRALAAGYFHNLALT 527
P V L + + +A G H++A T
Sbjct: 3293 TTTVNRKPTLVQGLEGQKITRVACGSSHSVAWT 3325
Score = 68.5 bits (160), Expect = 1e-10
Identities = 56/220 (25%), Positives = 90/220 (40%), Gaps = 21/220 (9%)
Query: 412 VCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGAC 471
V V +G H A+ + G + +WG G+LG GN P+++ G +V V G
Sbjct: 4042 VAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGA 4101
Query: 472 HSVLLTRGGELWACGASVFGQLG---TGQRGKASLPVRVALHEPVR-ALAAGYFHNLALT 527
HS +T G+L+ G +G+LG + + K L + H V A +G L LT
Sbjct: 4102 HSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLT 4161
Query: 528 HKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISA 587
V+ WG +D P +D+ G +V++
Sbjct: 4162 DDDTVWSWGDGDYGKLG----------------RGGSDGCKVPMKIDSLTGLG-VVKVEC 4204
Query: 588 GWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
G S + G++YTWG +LG G ++ P +V+
Sbjct: 4205 GSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQ 4244
Score = 65.3 bits (152), Expect = 1e-09
Identities = 53/210 (25%), Positives = 94/210 (44%), Gaps = 23/210 (10%)
Query: 423 AVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLV--TKFLGRKVQSVGCGACHSVLLTRGG 480
AV A G+L G+G G+LG+G + TP L+ + + K +V G H + L+ G
Sbjct: 3999 AVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEG 4058
Query: 481 ELWACGASVFGQLGTGQRGKASLPVRVALHEPVRA--LAAGYFHNLALTHKGEVYVWGAS 538
E+++ G + G+LG G R P + + +AAG H+ +T G++Y WG
Sbjct: 4059 EVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKG 4118
Query: 539 PQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQIS--AGWHHSCIIN 596
H D++ L P V+ R+V I+ +G + +
Sbjct: 4119 RYGRLG----------------HSDSEDQLKPKLVEALQGH-RVVDIACGSGDAQTLCLT 4161
Query: 597 NMGSIYTWGLNFDGQLGSGDRKQIQIPTEV 626
+ ++++WG G+LG G ++P ++
Sbjct: 4162 DDDTVWSWGDGDYGKLGRGGSDGCKVPMKI 4191
Score = 58.4 bits (135), Expect = 1e-07
Identities = 61/202 (30%), Positives = 89/202 (44%), Gaps = 29/202 (14%)
Query: 424 VDAGGRLLTWGWGVHGQLGLGNIDDQW----TPQLVTKFLGRKVQSVGCGACHSVLLTRG 479
+ AGG +GWG + + LG I+ TP L R VQ +G G +T
Sbjct: 3946 LSAGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATL-RPVQLIG-GEQTLFAVTAD 4003
Query: 480 GELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALA--AGYFHNLALTHKGEVYVW 535
G+L+A G G+LG G S P + H ++ +A +G H LAL+ +GEVY W
Sbjct: 4004 GKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSW 4063
Query: 536 GASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRG-RIVQISAGWHHSCI 594
G E L H + P ++ ++RG +V ++AG HS
Sbjct: 4064 G---------------EAEDGKLG-HGNRSPCDRPRVIE--SLRGIEVVDVAAGGAHSAC 4105
Query: 595 INNMGSIYTWGLNFDGQLGSGD 616
+ G +YTWG G+LG D
Sbjct: 4106 VTAAGDLYTWGKGRYGRLGHSD 4127
Score = 56.4 bits (130), Expect = 5e-07
Identities = 61/219 (27%), Positives = 88/219 (40%), Gaps = 24/219 (10%)
Query: 415 AAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSV 474
AAG +A + ++ WG QLG P V V G+
Sbjct: 2948 AAGLESAATIRT--KVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLF 3005
Query: 475 LLTRGGELWACGASVFGQLGTG-QRGKASLPVRV-ALHEPVR---ALAAGYFHNLALTHK 529
+T G+++ACG + G+LG G G +P ++ AL V A+ +G H ALT
Sbjct: 3006 AVTVEGKVYACGEATNGRLGLGISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVD 3065
Query: 530 GEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGW 589
G+V+ WG E L H P ++ + RI I+ G
Sbjct: 3066 GKVFSWG---------------EGDDGKLG-HFSRMNCDKPRLIEALKTK-RIRDIACGS 3108
Query: 590 HHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKI 628
HS + + G +YTWGL G+LG GD P VK+
Sbjct: 3109 SHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKV 3147
Score = 35.9 bits (79), Expect = 0.72
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 3/62 (4%)
Query: 564 NDRYLAPSCVDTTNVRGRIVQISA--GWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQ 621
N LAP V R IV+I+A HH + G +Y+WG G+LG GD ++
Sbjct: 478 NSDTLAPQLVQGLASRN-IVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLE 536
Query: 622 IP 623
P
Sbjct: 537 EP 538
Score = 32.7 bits (71), Expect = 6.7
Identities = 13/36 (36%), Positives = 21/36 (58%)
Query: 599 GSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQP 634
G+IY WG N GQLG + ++++PT + +P
Sbjct: 3952 GTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRP 3987
>X97668-1|CAA66258.1| 815|Homo sapiens XLRP3 protein.
Length = 815
Score = 98.3 bits (234), Expect = 1e-19
Identities = 87/299 (29%), Positives = 130/299 (43%), Gaps = 33/299 (11%)
Query: 322 GLAHWAVVSDGNARVMMASTPVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQL 380
G +W + G+ + T V +V ACGR+HTL+ TE G +Y+ G N GQL
Sbjct: 60 GSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQL 119
Query: 381 XXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQ 440
+++ ++AG SAA+ GRL WG GQ
Sbjct: 120 GLGDTEERNTFHVISFFTSEHKIKQ--------LSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 441 LGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQR-- 498
+GL N+ + PQ VT +G+ V + CG HS +T GEL+ G G+LG +
Sbjct: 172 IGLKNVSNVCVPQQVT--IGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLL 229
Query: 499 GKASLPVRVA-LHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPT 557
G P V+ + E V +A G H + LT + VY +G Q E S P
Sbjct: 230 GNHRTPQLVSEIPEKVIQVACGGEHTVVLT-ENAVYTFGLG-QFGQLGLGTFLFETSEPK 287
Query: 558 LPFHDDNDRYLAPSCVDTTNVRGRIVQ-ISAGWHHSCIINNMGSIYTWGLNFDGQLGSG 615
+ N+R + + IS G +H+ +I ++G +YT+G G+LG G
Sbjct: 288 V----------------IENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLG 330
Score = 92.7 bits (220), Expect = 6e-18
Identities = 70/267 (26%), Positives = 122/267 (45%), Gaps = 30/267 (11%)
Query: 352 IDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAP 410
+ ++CG H+ ++T N LY G N +GQL +V+LA
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPE-KVKLA---- 92
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGR-KVQSVGCG 469
A G H+ GG + G GQLGLG+ +++ T +++ F K++ + G
Sbjct: 93 ----ACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAG 148
Query: 470 ACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHK 529
+ S LT G L+ G + GQ+G +P +V + +PV ++ GY+H+ +T
Sbjct: 149 SNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIGKPVSWISCGYYHSAFVTTD 208
Query: 530 GEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDD-NDRYLAPSCVDTTNVRGRIVQISAG 588
GE+YV+G EP + L + + P V + + +++Q++ G
Sbjct: 209 GELYVFG---------------EPENGKLGLPNQLLGNHRTPQLV--SEIPEKVIQVACG 251
Query: 589 WHHSCIINNMGSIYTWGLNFDGQLGSG 615
H+ ++ ++YT+GL GQLG G
Sbjct: 252 GEHTVVLTE-NAVYTFGLGQFGQLGLG 277
Score = 73.3 bits (172), Expect = 4e-12
Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 10/133 (7%)
Query: 345 TELIGRVIDVACGRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVR 404
+E+ +VI VACG HT++LTEN +Y+ G FGQL + +R
Sbjct: 239 SEIPEKVIQVACGGEHTVVLTENAVYTFGLGQFGQLGLGTFLFETSEPKV-----IENIR 293
Query: 405 LAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG--NIDDQWTPQLVTKFLGRK 462
+ ++ G H+A + G + T+G G HG+LGLG N + + P L + FL
Sbjct: 294 ---DQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFI 350
Query: 463 VQSVGCGACHSVL 475
V+ V CG CH V+
Sbjct: 351 VKLVACGGCHMVV 363
Score = 59.7 bits (138), Expect = 5e-08
Identities = 45/165 (27%), Positives = 72/165 (43%), Gaps = 18/165 (10%)
Query: 466 VGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHN 523
+ CG HS ++T +L+ G++ +GQLG G + S P V+ E V+ A G H
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHT 99
Query: 524 LALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIV 583
L T G VY G + + L D +R + +I
Sbjct: 100 LVSTEGGNVYATGGN---------------NEGQLGLGDTEERNTF-HVISFFTSEHKIK 143
Query: 584 QISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKI 628
Q+SAG + S + G ++ WG N +GQ+G + + +P +V I
Sbjct: 144 QLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTI 188
Score = 39.1 bits (87), Expect = 0.077
Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 25/135 (18%)
Query: 583 VQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMKSDSE 642
V +S G HS ++ +Y +G N GQLG G + I PT VK +P +K
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVK---ALKPEKVK---- 90
Query: 643 KTTDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTGNTH---LQISNEKTKGGNRVIMM 699
L CG + T+ + G +Y+TG + L + + + + VI
Sbjct: 91 ---------------LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISF 135
Query: 700 KTTKRVIKIPASRTN 714
T++ IK ++ +N
Sbjct: 136 FTSEHKIKQLSAGSN 150
>U57629-1|AAC50481.1| 815|Homo sapiens retinitis pigmentosa GTPase
regulator protein.
Length = 815
Score = 98.3 bits (234), Expect = 1e-19
Identities = 87/299 (29%), Positives = 130/299 (43%), Gaps = 33/299 (11%)
Query: 322 GLAHWAVVSDGNARVMMASTPVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQL 380
G +W + G+ + T V +V ACGR+HTL+ TE G +Y+ G N GQL
Sbjct: 60 GSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQL 119
Query: 381 XXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQ 440
+++ ++AG SAA+ GRL WG GQ
Sbjct: 120 GLGDTEERNTFHVISFFTSEHKIKQ--------LSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 441 LGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQR-- 498
+GL N+ + PQ VT +G+ V + CG HS +T GEL+ G G+LG +
Sbjct: 172 IGLKNVSNVCVPQQVT--IGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLL 229
Query: 499 GKASLPVRVA-LHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPT 557
G P V+ + E V +A G H + LT + VY +G Q E S P
Sbjct: 230 GNHRTPQLVSEIPEKVIQVACGGEHTVVLT-ENAVYTFGLG-QFGQLGLGTFLFETSEPK 287
Query: 558 LPFHDDNDRYLAPSCVDTTNVRGRIVQ-ISAGWHHSCIINNMGSIYTWGLNFDGQLGSG 615
+ N+R + + IS G +H+ +I ++G +YT+G G+LG G
Sbjct: 288 V----------------IENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLG 330
Score = 92.7 bits (220), Expect = 6e-18
Identities = 70/267 (26%), Positives = 122/267 (45%), Gaps = 30/267 (11%)
Query: 352 IDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAP 410
+ ++CG H+ ++T N LY G N +GQL +V+LA
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPE-KVKLA---- 92
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGR-KVQSVGCG 469
A G H+ GG + G GQLGLG+ +++ T +++ F K++ + G
Sbjct: 93 ----ACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAG 148
Query: 470 ACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHK 529
+ S LT G L+ G + GQ+G +P +V + +PV ++ GY+H+ +T
Sbjct: 149 SNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIGKPVSWISCGYYHSAFVTTD 208
Query: 530 GEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDD-NDRYLAPSCVDTTNVRGRIVQISAG 588
GE+YV+G EP + L + + P V + + +++Q++ G
Sbjct: 209 GELYVFG---------------EPENGKLGLPNQLLGNHRTPQLV--SEIPEKVIQVACG 251
Query: 589 WHHSCIINNMGSIYTWGLNFDGQLGSG 615
H+ ++ ++YT+GL GQLG G
Sbjct: 252 GEHTVVLTE-NAVYTFGLGQFGQLGLG 277
Score = 73.3 bits (172), Expect = 4e-12
Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 10/133 (7%)
Query: 345 TELIGRVIDVACGRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVR 404
+E+ +VI VACG HT++LTEN +Y+ G FGQL + +R
Sbjct: 239 SEIPEKVIQVACGGEHTVVLTENAVYTFGLGQFGQLGLGTFLFETSEPKV-----IENIR 293
Query: 405 LAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG--NIDDQWTPQLVTKFLGRK 462
+ ++ G H+A + G + T+G G HG+LGLG N + + P L + FL
Sbjct: 294 ---DQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFI 350
Query: 463 VQSVGCGACHSVL 475
V+ V CG CH V+
Sbjct: 351 VKLVACGGCHMVV 363
Score = 59.7 bits (138), Expect = 5e-08
Identities = 45/165 (27%), Positives = 72/165 (43%), Gaps = 18/165 (10%)
Query: 466 VGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHN 523
+ CG HS ++T +L+ G++ +GQLG G + S P V+ E V+ A G H
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHT 99
Query: 524 LALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIV 583
L T G VY G + + L D +R + +I
Sbjct: 100 LVSTEGGNVYATGGN---------------NEGQLGLGDTEERNTF-HVISFFTSEHKIK 143
Query: 584 QISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKI 628
Q+SAG + S + G ++ WG N +GQ+G + + +P +V I
Sbjct: 144 QLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTI 188
Score = 39.1 bits (87), Expect = 0.077
Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 25/135 (18%)
Query: 583 VQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMKSDSE 642
V +S G HS ++ +Y +G N GQLG G + I PT VK +P +K
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVK---ALKPEKVK---- 90
Query: 643 KTTDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTGNTH---LQISNEKTKGGNRVIMM 699
L CG + T+ + G +Y+TG + L + + + + VI
Sbjct: 91 ---------------LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISF 135
Query: 700 KTTKRVIKIPASRTN 714
T++ IK ++ +N
Sbjct: 136 FTSEHKIKQLSAGSN 150
>BC031624-1|AAH31624.1| 480|Homo sapiens RPGR protein protein.
Length = 480
Score = 98.3 bits (234), Expect = 1e-19
Identities = 87/299 (29%), Positives = 130/299 (43%), Gaps = 33/299 (11%)
Query: 322 GLAHWAVVSDGNARVMMASTPVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQL 380
G +W + G+ + T V +V ACGR+HTL+ TE G +Y+ G N GQL
Sbjct: 60 GSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQL 119
Query: 381 XXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQ 440
+++ ++AG SAA+ GRL WG GQ
Sbjct: 120 GLGDTEERNTFHVISFFTSEHKIKQ--------LSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 441 LGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQR-- 498
+GL N+ + PQ VT +G+ V + CG HS +T GEL+ G G+LG +
Sbjct: 172 IGLKNVSNVCVPQQVT--IGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLL 229
Query: 499 GKASLPVRVA-LHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPT 557
G P V+ + E V +A G H + LT + VY +G Q E S P
Sbjct: 230 GNHRTPQLVSEIPEKVIQVACGGEHTVVLT-ENAVYTFGLG-QFGQLGLGTFLFETSEPK 287
Query: 558 LPFHDDNDRYLAPSCVDTTNVRGRIVQ-ISAGWHHSCIINNMGSIYTWGLNFDGQLGSG 615
+ N+R + + IS G +H+ +I ++G +YT+G G+LG G
Sbjct: 288 V----------------IENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLG 330
Score = 92.7 bits (220), Expect = 6e-18
Identities = 70/267 (26%), Positives = 122/267 (45%), Gaps = 30/267 (11%)
Query: 352 IDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAP 410
+ ++CG H+ ++T N LY G N +GQL +V+LA
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPE-KVKLA---- 92
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGR-KVQSVGCG 469
A G H+ GG + G GQLGLG+ +++ T +++ F K++ + G
Sbjct: 93 ----ACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAG 148
Query: 470 ACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHK 529
+ S LT G L+ G + GQ+G +P +V + +PV ++ GY+H+ +T
Sbjct: 149 SNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIGKPVSWISCGYYHSAFVTTD 208
Query: 530 GEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDD-NDRYLAPSCVDTTNVRGRIVQISAG 588
GE+YV+G EP + L + + P V + + +++Q++ G
Sbjct: 209 GELYVFG---------------EPENGKLGLPNQLLGNHRTPQLV--SEIPEKVIQVACG 251
Query: 589 WHHSCIINNMGSIYTWGLNFDGQLGSG 615
H+ ++ ++YT+GL GQLG G
Sbjct: 252 GEHTVVLTE-NAVYTFGLGQFGQLGLG 277
Score = 73.3 bits (172), Expect = 4e-12
Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 10/133 (7%)
Query: 345 TELIGRVIDVACGRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVR 404
+E+ +VI VACG HT++LTEN +Y+ G FGQL + +R
Sbjct: 239 SEIPEKVIQVACGGEHTVVLTENAVYTFGLGQFGQLGLGTFLFETSEPKV-----IENIR 293
Query: 405 LAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG--NIDDQWTPQLVTKFLGRK 462
+ ++ G H+A + G + T+G G HG+LGLG N + + P L + FL
Sbjct: 294 ---DQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFI 350
Query: 463 VQSVGCGACHSVL 475
V+ V CG CH V+
Sbjct: 351 VKLVACGGCHMVV 363
Score = 59.7 bits (138), Expect = 5e-08
Identities = 45/165 (27%), Positives = 72/165 (43%), Gaps = 18/165 (10%)
Query: 466 VGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHN 523
+ CG HS ++T +L+ G++ +GQLG G + S P V+ E V+ A G H
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHT 99
Query: 524 LALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIV 583
L T G VY G + + L D +R + +I
Sbjct: 100 LVSTEGGNVYATGGN---------------NEGQLGLGDTEERNTF-HVISFFTSEHKIK 143
Query: 584 QISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKI 628
Q+SAG + S + G ++ WG N +GQ+G + + +P +V I
Sbjct: 144 QLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTI 188
Score = 39.1 bits (87), Expect = 0.077
Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 25/135 (18%)
Query: 583 VQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMKSDSE 642
V +S G HS ++ +Y +G N GQLG G + I PT VK +P +K
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVK---ALKPEKVK---- 90
Query: 643 KTTDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTGNTH---LQISNEKTKGGNRVIMM 699
L CG + T+ + G +Y+TG + L + + + + VI
Sbjct: 91 ---------------LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISF 135
Query: 700 KTTKRVIKIPASRTN 714
T++ IK ++ +N
Sbjct: 136 FTSEHKIKQLSAGSN 150
>AL606748-2|CAI95407.1| 815|Homo sapiens retinitis pigmentosa
GTPase regulator protein.
Length = 815
Score = 98.3 bits (234), Expect = 1e-19
Identities = 87/299 (29%), Positives = 130/299 (43%), Gaps = 33/299 (11%)
Query: 322 GLAHWAVVSDGNARVMMASTPVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQL 380
G +W + G+ + T V +V ACGR+HTL+ TE G +Y+ G N GQL
Sbjct: 60 GSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQL 119
Query: 381 XXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQ 440
+++ ++AG SAA+ GRL WG GQ
Sbjct: 120 GLGDTEERNTFHVISFFTSEHKIKQ--------LSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 441 LGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQR-- 498
+GL N+ + PQ VT +G+ V + CG HS +T GEL+ G G+LG +
Sbjct: 172 IGLKNVSNVCVPQQVT--IGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLL 229
Query: 499 GKASLPVRVA-LHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPT 557
G P V+ + E V +A G H + LT + VY +G Q E S P
Sbjct: 230 GNHRTPQLVSEIPEKVIQVACGGEHTVVLT-ENAVYTFGLG-QFGQLGLGTFLFETSEPK 287
Query: 558 LPFHDDNDRYLAPSCVDTTNVRGRIVQ-ISAGWHHSCIINNMGSIYTWGLNFDGQLGSG 615
+ N+R + + IS G +H+ +I ++G +YT+G G+LG G
Sbjct: 288 V----------------IENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLG 330
Score = 92.7 bits (220), Expect = 6e-18
Identities = 70/267 (26%), Positives = 122/267 (45%), Gaps = 30/267 (11%)
Query: 352 IDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAP 410
+ ++CG H+ ++T N LY G N +GQL +V+LA
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPE-KVKLA---- 92
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGR-KVQSVGCG 469
A G H+ GG + G GQLGLG+ +++ T +++ F K++ + G
Sbjct: 93 ----ACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAG 148
Query: 470 ACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHK 529
+ S LT G L+ G + GQ+G +P +V + +PV ++ GY+H+ +T
Sbjct: 149 SNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIGKPVSWISCGYYHSAFVTTD 208
Query: 530 GEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDD-NDRYLAPSCVDTTNVRGRIVQISAG 588
GE+YV+G EP + L + + P V + + +++Q++ G
Sbjct: 209 GELYVFG---------------EPENGKLGLPNQLLGNHRTPQLV--SEIPEKVIQVACG 251
Query: 589 WHHSCIINNMGSIYTWGLNFDGQLGSG 615
H+ ++ ++YT+GL GQLG G
Sbjct: 252 GEHTVVLTE-NAVYTFGLGQFGQLGLG 277
Score = 73.3 bits (172), Expect = 4e-12
Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 10/133 (7%)
Query: 345 TELIGRVIDVACGRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVR 404
+E+ +VI VACG HT++LTEN +Y+ G FGQL + +R
Sbjct: 239 SEIPEKVIQVACGGEHTVVLTENAVYTFGLGQFGQLGLGTFLFETSEPKV-----IENIR 293
Query: 405 LAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG--NIDDQWTPQLVTKFLGRK 462
+ ++ G H+A + G + T+G G HG+LGLG N + + P L + FL
Sbjct: 294 ---DQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFI 350
Query: 463 VQSVGCGACHSVL 475
V+ V CG CH V+
Sbjct: 351 VKLVACGGCHMVV 363
Score = 59.7 bits (138), Expect = 5e-08
Identities = 45/165 (27%), Positives = 72/165 (43%), Gaps = 18/165 (10%)
Query: 466 VGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHN 523
+ CG HS ++T +L+ G++ +GQLG G + S P V+ E V+ A G H
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHT 99
Query: 524 LALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIV 583
L T G VY G + + L D +R + +I
Sbjct: 100 LVSTEGGNVYATGGN---------------NEGQLGLGDTEERNTF-HVISFFTSEHKIK 143
Query: 584 QISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKI 628
Q+SAG + S + G ++ WG N +GQ+G + + +P +V I
Sbjct: 144 QLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTI 188
Score = 39.1 bits (87), Expect = 0.077
Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 25/135 (18%)
Query: 583 VQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMKSDSE 642
V +S G HS ++ +Y +G N GQLG G + I PT VK +P +K
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVK---ALKPEKVK---- 90
Query: 643 KTTDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTGNTH---LQISNEKTKGGNRVIMM 699
L CG + T+ + G +Y+TG + L + + + + VI
Sbjct: 91 ---------------LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISF 135
Query: 700 KTTKRVIKIPASRTN 714
T++ IK ++ +N
Sbjct: 136 FTSEHKIKQLSAGSN 150
>AK223491-1|BAD97211.1| 815|Homo sapiens retinitis pigmentosa
GTPase regulator variant protein.
Length = 815
Score = 98.3 bits (234), Expect = 1e-19
Identities = 87/299 (29%), Positives = 130/299 (43%), Gaps = 33/299 (11%)
Query: 322 GLAHWAVVSDGNARVMMASTPVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQL 380
G +W + G+ + T V +V ACGR+HTL+ TE G +Y+ G N GQL
Sbjct: 60 GSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQL 119
Query: 381 XXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQ 440
+++ ++AG SAA+ GRL WG GQ
Sbjct: 120 GLGDTEERNTFHVISFFTSEHKIKQ--------LSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 441 LGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQR-- 498
+GL N+ + PQ VT +G+ V + CG HS +T GEL+ G G+LG +
Sbjct: 172 IGLKNVSNVCVPQQVT--IGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLL 229
Query: 499 GKASLPVRVA-LHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPT 557
G P V+ + E V +A G H + LT + VY +G Q E S P
Sbjct: 230 GNHRTPQLVSEIPEKVIQVACGGEHTVVLT-ENAVYTFGLG-QFGQLGLGTFLFETSEPK 287
Query: 558 LPFHDDNDRYLAPSCVDTTNVRGRIVQ-ISAGWHHSCIINNMGSIYTWGLNFDGQLGSG 615
+ N+R + + IS G +H+ +I ++G +YT+G G+LG G
Sbjct: 288 V----------------IENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLG 330
Score = 92.7 bits (220), Expect = 6e-18
Identities = 70/267 (26%), Positives = 122/267 (45%), Gaps = 30/267 (11%)
Query: 352 IDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAP 410
+ ++CG H+ ++T N LY G N +GQL +V+LA
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPE-KVKLA---- 92
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGR-KVQSVGCG 469
A G H+ GG + G GQLGLG+ +++ T +++ F K++ + G
Sbjct: 93 ----ACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAG 148
Query: 470 ACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHK 529
+ S LT G L+ G + GQ+G +P +V + +PV ++ GY+H+ +T
Sbjct: 149 SNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIGKPVSWISCGYYHSAFVTTD 208
Query: 530 GEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDD-NDRYLAPSCVDTTNVRGRIVQISAG 588
GE+YV+G EP + L + + P V + + +++Q++ G
Sbjct: 209 GELYVFG---------------EPENGKLGLPNQLLGNHRTPQLV--SEIPEKVIQVACG 251
Query: 589 WHHSCIINNMGSIYTWGLNFDGQLGSG 615
H+ ++ ++YT+GL GQLG G
Sbjct: 252 GEHTVVLTE-NAVYTFGLGQFGQLGLG 277
Score = 73.3 bits (172), Expect = 4e-12
Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 10/133 (7%)
Query: 345 TELIGRVIDVACGRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVR 404
+E+ +VI VACG HT++LTEN +Y+ G FGQL + +R
Sbjct: 239 SEIPEKVIQVACGGEHTVVLTENAVYTFGLGQFGQLGLGTFLFETSEPKV-----IENIR 293
Query: 405 LAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG--NIDDQWTPQLVTKFLGRK 462
+ ++ G H+A + G + T+G G HG+LGLG N + + P L + FL
Sbjct: 294 ---DQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFI 350
Query: 463 VQSVGCGACHSVL 475
V+ V CG CH V+
Sbjct: 351 VKLVACGGCHMVV 363
Score = 59.7 bits (138), Expect = 5e-08
Identities = 45/165 (27%), Positives = 72/165 (43%), Gaps = 18/165 (10%)
Query: 466 VGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHN 523
+ CG HS ++T +L+ G++ +GQLG G + S P V+ E V+ A G H
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHT 99
Query: 524 LALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIV 583
L T G VY G + + L D +R + +I
Sbjct: 100 LVSTEGGNVYATGGN---------------NEGQLGLGDTEERNTF-HVISFFTSEHKIK 143
Query: 584 QISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKI 628
Q+SAG + S + G ++ WG N +GQ+G + + +P +V I
Sbjct: 144 QLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTI 188
Score = 39.1 bits (87), Expect = 0.077
Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 25/135 (18%)
Query: 583 VQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMKSDSE 642
V +S G HS ++ +Y +G N GQLG G + I PT VK +P +K
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVK---ALKPEKVK---- 90
Query: 643 KTTDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTGNTH---LQISNEKTKGGNRVIMM 699
L CG + T+ + G +Y+TG + L + + + + VI
Sbjct: 91 ---------------LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISF 135
Query: 700 KTTKRVIKIPASRTN 714
T++ IK ++ +N
Sbjct: 136 FTSEHKIKQLSAGSN 150
>AJ238395-1|CAB54002.1| 646|Homo sapiens RPGR protein protein.
Length = 646
Score = 98.3 bits (234), Expect = 1e-19
Identities = 87/299 (29%), Positives = 130/299 (43%), Gaps = 33/299 (11%)
Query: 322 GLAHWAVVSDGNARVMMASTPVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQL 380
G +W + G+ + T V +V ACGR+HTL+ TE G +Y+ G N GQL
Sbjct: 60 GSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQL 119
Query: 381 XXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQ 440
+++ ++AG SAA+ GRL WG GQ
Sbjct: 120 GLGDTEERNTFHVISFFTSEHKIKQ--------LSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 441 LGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQR-- 498
+GL N+ + PQ VT +G+ V + CG HS +T GEL+ G G+LG +
Sbjct: 172 IGLKNVSNVCVPQQVT--IGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLL 229
Query: 499 GKASLPVRVA-LHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPT 557
G P V+ + E V +A G H + LT + VY +G Q E S P
Sbjct: 230 GNHRTPQLVSEIPEKVIQVACGGEHTVVLT-ENAVYTFGLG-QFGQLGLGTFLFETSEPK 287
Query: 558 LPFHDDNDRYLAPSCVDTTNVRGRIVQ-ISAGWHHSCIINNMGSIYTWGLNFDGQLGSG 615
+ N+R + + IS G +H+ +I ++G +YT+G G+LG G
Sbjct: 288 V----------------IENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLG 330
Score = 92.7 bits (220), Expect = 6e-18
Identities = 70/267 (26%), Positives = 122/267 (45%), Gaps = 30/267 (11%)
Query: 352 IDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAP 410
+ ++CG H+ ++T N LY G N +GQL +V+LA
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPE-KVKLA---- 92
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGR-KVQSVGCG 469
A G H+ GG + G GQLGLG+ +++ T +++ F K++ + G
Sbjct: 93 ----ACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAG 148
Query: 470 ACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHK 529
+ S LT G L+ G + GQ+G +P +V + +PV ++ GY+H+ +T
Sbjct: 149 SNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIGKPVSWISCGYYHSAFVTTD 208
Query: 530 GEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDD-NDRYLAPSCVDTTNVRGRIVQISAG 588
GE+YV+G EP + L + + P V + + +++Q++ G
Sbjct: 209 GELYVFG---------------EPENGKLGLPNQLLGNHRTPQLV--SEIPEKVIQVACG 251
Query: 589 WHHSCIINNMGSIYTWGLNFDGQLGSG 615
H+ ++ ++YT+GL GQLG G
Sbjct: 252 GEHTVVLTE-NAVYTFGLGQFGQLGLG 277
Score = 73.3 bits (172), Expect = 4e-12
Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 10/133 (7%)
Query: 345 TELIGRVIDVACGRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVR 404
+E+ +VI VACG HT++LTEN +Y+ G FGQL + +R
Sbjct: 239 SEIPEKVIQVACGGEHTVVLTENAVYTFGLGQFGQLGLGTFLFETSEPKV-----IENIR 293
Query: 405 LAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG--NIDDQWTPQLVTKFLGRK 462
+ ++ G H+A + G + T+G G HG+LGLG N + + P L + FL
Sbjct: 294 ---DQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFI 350
Query: 463 VQSVGCGACHSVL 475
V+ V CG CH V+
Sbjct: 351 VKLVACGGCHMVV 363
Score = 59.7 bits (138), Expect = 5e-08
Identities = 45/165 (27%), Positives = 72/165 (43%), Gaps = 18/165 (10%)
Query: 466 VGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHN 523
+ CG HS ++T +L+ G++ +GQLG G + S P V+ E V+ A G H
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHT 99
Query: 524 LALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIV 583
L T G VY G + + L D +R + +I
Sbjct: 100 LVSTEGGNVYATGGN---------------NEGQLGLGDTEERNTF-HVISFFTSEHKIK 143
Query: 584 QISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKI 628
Q+SAG + S + G ++ WG N +GQ+G + + +P +V I
Sbjct: 144 QLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTI 188
Score = 39.1 bits (87), Expect = 0.077
Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 25/135 (18%)
Query: 583 VQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMKSDSE 642
V +S G HS ++ +Y +G N GQLG G + I PT VK +P +K
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVK---ALKPEKVK---- 90
Query: 643 KTTDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTGNTH---LQISNEKTKGGNRVIMM 699
L CG + T+ + G +Y+TG + L + + + + VI
Sbjct: 91 ---------------LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISF 135
Query: 700 KTTKRVIKIPASRTN 714
T++ IK ++ +N
Sbjct: 136 FTSEHKIKQLSAGSN 150
>AJ318463-1|CAC86116.1| 815|Homo sapiens retinitis pigmentosa
GTPase regulator protein.
Length = 815
Score = 97.5 bits (232), Expect = 2e-19
Identities = 87/299 (29%), Positives = 129/299 (43%), Gaps = 33/299 (11%)
Query: 322 GLAHWAVVSDGNARVMMASTPVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQL 380
G +W + G+ + T V +V ACGR+HTL+ TE G +Y+ G N GQL
Sbjct: 60 GSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQL 119
Query: 381 XXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQ 440
+++ ++AG SAA+ GRL WG GQ
Sbjct: 120 GLGDTEERNTFHVISFFTSEHKIKQ--------LSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 441 LGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQR-- 498
+GL N+ + PQ VT +G V + CG HS +T GEL+ G G+LG +
Sbjct: 172 IGLKNVSNVCVPQQVT--IGNPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLL 229
Query: 499 GKASLPVRVA-LHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPT 557
G P V+ + E V +A G H + LT + VY +G Q E S P
Sbjct: 230 GNHRTPQLVSEIPEKVIQVACGGEHTVVLT-ENAVYTFGLG-QFGQLGLGTFLFETSEPK 287
Query: 558 LPFHDDNDRYLAPSCVDTTNVRGRIVQ-ISAGWHHSCIINNMGSIYTWGLNFDGQLGSG 615
+ N+R + + IS G +H+ +I ++G +YT+G G+LG G
Sbjct: 288 V----------------IENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLG 330
Score = 92.3 bits (219), Expect = 8e-18
Identities = 70/267 (26%), Positives = 121/267 (45%), Gaps = 30/267 (11%)
Query: 352 IDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAP 410
+ ++CG H+ ++T N LY G N +GQL +V+LA
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPE-KVKLA---- 92
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGR-KVQSVGCG 469
A G H+ GG + G GQLGLG+ +++ T +++ F K++ + G
Sbjct: 93 ----ACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAG 148
Query: 470 ACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHK 529
+ S LT G L+ G + GQ+G +P +V + PV ++ GY+H+ +T
Sbjct: 149 SNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIGNPVSWISCGYYHSAFVTTD 208
Query: 530 GEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDD-NDRYLAPSCVDTTNVRGRIVQISAG 588
GE+YV+G EP + L + + P V + + +++Q++ G
Sbjct: 209 GELYVFG---------------EPENGKLGLPNQLLGNHRTPQLV--SEIPEKVIQVACG 251
Query: 589 WHHSCIINNMGSIYTWGLNFDGQLGSG 615
H+ ++ ++YT+GL GQLG G
Sbjct: 252 GEHTVVLTE-NAVYTFGLGQFGQLGLG 277
Score = 73.3 bits (172), Expect = 4e-12
Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 10/133 (7%)
Query: 345 TELIGRVIDVACGRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVR 404
+E+ +VI VACG HT++LTEN +Y+ G FGQL + +R
Sbjct: 239 SEIPEKVIQVACGGEHTVVLTENAVYTFGLGQFGQLGLGTFLFETSEPKV-----IENIR 293
Query: 405 LAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG--NIDDQWTPQLVTKFLGRK 462
+ ++ G H+A + G + T+G G HG+LGLG N + + P L + FL
Sbjct: 294 ---DQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFI 350
Query: 463 VQSVGCGACHSVL 475
V+ V CG CH V+
Sbjct: 351 VKLVACGGCHMVV 363
Score = 59.7 bits (138), Expect = 5e-08
Identities = 45/165 (27%), Positives = 72/165 (43%), Gaps = 18/165 (10%)
Query: 466 VGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHN 523
+ CG HS ++T +L+ G++ +GQLG G + S P V+ E V+ A G H
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHT 99
Query: 524 LALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIV 583
L T G VY G + + L D +R + +I
Sbjct: 100 LVSTEGGNVYATGGN---------------NEGQLGLGDTEERNTF-HVISFFTSEHKIK 143
Query: 584 QISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKI 628
Q+SAG + S + G ++ WG N +GQ+G + + +P +V I
Sbjct: 144 QLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTI 188
Score = 39.1 bits (87), Expect = 0.077
Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 25/135 (18%)
Query: 583 VQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMKSDSE 642
V +S G HS ++ +Y +G N GQLG G + I PT VK +P +K
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVK---ALKPEKVK---- 90
Query: 643 KTTDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTGNTH---LQISNEKTKGGNRVIMM 699
L CG + T+ + G +Y+TG + L + + + + VI
Sbjct: 91 ---------------LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISF 135
Query: 700 KTTKRVIKIPASRTN 714
T++ IK ++ +N
Sbjct: 136 FTSEHKIKQLSAGSN 150
>AF225407-1|AAO27483.1| 409|Homo sapiens HERC2 protein.
Length = 409
Score = 97.5 bits (232), Expect = 2e-19
Identities = 66/213 (30%), Positives = 95/213 (44%), Gaps = 21/213 (9%)
Query: 415 AAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA--CH 472
AAG HSA V A G L TWG G +G+LG + +DQ P+LV G +V + CG+
Sbjct: 1 AAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQ 60
Query: 473 SVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV--ALHEPVRALAAGYFHNLALTHKG 530
++ LT +W+ G +G+LG G +P+++ V + G ++ALT G
Sbjct: 61 TLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSG 120
Query: 531 EVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWH 590
VY WG H +D P V + +++ I+ G
Sbjct: 121 AVYTWGKGDYHRLG----------------HGSDDHVRRPRQVQGLQGK-KVIAIATGSL 163
Query: 591 HSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIP 623
H G +YTWG N +GQLG G IQ P
Sbjct: 164 HCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRP 196
Score = 72.5 bits (170), Expect = 7e-12
Identities = 56/181 (30%), Positives = 83/181 (45%), Gaps = 14/181 (7%)
Query: 350 RVIDVACGRH--HTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLA 406
RV+D+ACG TL LT++ ++S GD +G+L +++
Sbjct: 48 RVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVP---------MKIDSL 98
Query: 407 GGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSV 466
G +V V G S A+ G + TWG G + +LG G+ D P+ V G+KV ++
Sbjct: 99 TGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAI 158
Query: 467 GCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVAL--HEPVRALAAGYFHNL 524
G+ H V T GE++ G + GQLG G P VA + V +A G H L
Sbjct: 159 ATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTL 218
Query: 525 A 525
A
Sbjct: 219 A 219
Score = 40.3 bits (90), Expect = 0.033
Identities = 41/163 (25%), Positives = 62/163 (38%), Gaps = 21/163 (12%)
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV-AL--HEPVR-ALAAGYFHNL 524
G HS +T G+L+ G +G+LG P V AL H V A +G L
Sbjct: 3 GGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTL 62
Query: 525 ALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQ 584
LT V+ WG +D P +D+ G +V+
Sbjct: 63 CLTDDDTVWSWGDGDYGKLG----------------RGGSDGCKVPMKIDSLTGLG-VVK 105
Query: 585 ISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
+ G S + G++YTWG +LG G ++ P +V+
Sbjct: 106 VECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQ 148
>BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6
protein.
Length = 1022
Score = 93.1 bits (221), Expect = 4e-18
Identities = 77/268 (28%), Positives = 120/268 (44%), Gaps = 28/268 (10%)
Query: 351 VIDVACG-RHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
++ A G RH L+LT + + S GDN+ GQL ++
Sbjct: 25 LLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETLI-------- 76
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDD-QWTPQLVTKFLGRKVQSVGC 468
+ V+ G HS AV GR+ WG G GQLG+G + +TP+ + K+ V C
Sbjct: 77 -VDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSC 135
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQR-GKASLPVRVALHE--PVRALAAGYFHNLA 525
G HS+ L++ ++++ G + GQLG G+ + P RV E P+ +AAG H+ A
Sbjct: 136 GHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFA 195
Query: 526 LTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQI 585
L+ G + WG++ S +P + P V G +V I
Sbjct: 196 LSLCGTSFGWGSN--------SAGQLALSGRNVPVQSNK-----PLSVGALKNLG-VVYI 241
Query: 586 SAGWHHSCIINNMGSIYTWGLNFDGQLG 613
S G H+ ++ G ++T+G N GQLG
Sbjct: 242 SCGDAHTAVLTQDGKVFTFGDNRSGQLG 269
Score = 74.5 bits (175), Expect = 2e-12
Identities = 61/196 (31%), Positives = 88/196 (44%), Gaps = 14/196 (7%)
Query: 350 RVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
++I V+CG +H+L L+++ ++S G N+ GQL RVR G
Sbjct: 129 KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQ--------RVRSLEG 180
Query: 409 APLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG--NIDDQWT-PQLVTKFLGRKVQS 465
PL VAAG HS A+ G WG GQL L N+ Q P V V
Sbjct: 181 IPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVY 240
Query: 466 VGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV-ALHEPVRALAAGYFHNL 524
+ CG H+ +LT+ G+++ G + GQLG + P V + V + G +H L
Sbjct: 241 ISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGLVSQIDCGSYHTL 300
Query: 525 ALTH-KGEVYVWGASP 539
A H G+V +G P
Sbjct: 301 AYVHTTGQVVSFGHGP 316
Score = 69.3 bits (162), Expect = 6e-11
Identities = 62/222 (27%), Positives = 99/222 (44%), Gaps = 23/222 (10%)
Query: 402 RVRLAG--GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFL 459
R R AG GA L+ A+G HS + R+L+ G GQLG P+ +
Sbjct: 14 RRRTAGSPGAELLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALE 73
Query: 460 GRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASL-PVRVALHEPVRAL-- 516
V V CG HS+ + G ++A GA GQLG G+ + S P ++ ++ +
Sbjct: 74 TLIVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQV 133
Query: 517 AAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTT 576
+ G++H+LAL+ +V+ WG + S L + +P V
Sbjct: 134 SCGHYHSLALSKDSQVFSWGKN---------------SHGQLGLGKEFPSQASPQRV--R 176
Query: 577 NVRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDR 617
++ G + Q++AG HS ++ G+ + WG N GQL R
Sbjct: 177 SLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQLALSGR 218
Score = 38.7 bits (86), Expect = 0.10
Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 585 ISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRT 630
+S G HS + + G ++ WG +GQLG G+ K+I T KI T
Sbjct: 80 VSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISF-TPKKIMT 124
>AY653203-1|AAV66897.1| 322|Homo sapiens truncated HERC6 protein.
Length = 322
Score = 93.1 bits (221), Expect = 4e-18
Identities = 77/268 (28%), Positives = 120/268 (44%), Gaps = 28/268 (10%)
Query: 351 VIDVACG-RHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
++ A G RH L+LT + + S GDN+ GQL ++
Sbjct: 25 LLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETLI-------- 76
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDD-QWTPQLVTKFLGRKVQSVGC 468
+ V+ G HS AV GR+ WG G GQLG+G + +TP+ + K+ V C
Sbjct: 77 -VDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSC 135
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQR-GKASLPVRVALHE--PVRALAAGYFHNLA 525
G HS+ L++ ++++ G + GQLG G+ + P RV E P+ +AAG H+ A
Sbjct: 136 GHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFA 195
Query: 526 LTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQI 585
L+ G + WG++ S +P + P V G +V I
Sbjct: 196 LSLCGTSFGWGSN--------SAGQLALSGRNVPVQSNK-----PLSVGALKNLG-VVYI 241
Query: 586 SAGWHHSCIINNMGSIYTWGLNFDGQLG 613
S G H+ ++ G ++T+G N GQLG
Sbjct: 242 SCGDAHTAVLTQDGKVFTFGDNRSGQLG 269
Score = 69.3 bits (162), Expect = 6e-11
Identities = 62/222 (27%), Positives = 99/222 (44%), Gaps = 23/222 (10%)
Query: 402 RVRLAG--GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFL 459
R R AG GA L+ A+G HS + R+L+ G GQLG P+ +
Sbjct: 14 RRRTAGSPGAELLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALE 73
Query: 460 GRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASL-PVRVALHEPVRAL-- 516
V V CG HS+ + G ++A GA GQLG G+ + S P ++ ++ +
Sbjct: 74 TLIVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQV 133
Query: 517 AAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTT 576
+ G++H+LAL+ +V+ WG + S L + +P V
Sbjct: 134 SCGHYHSLALSKDSQVFSWGKN---------------SHGQLGLGKEFPSQASPQRV--R 176
Query: 577 NVRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDR 617
++ G + Q++AG HS ++ G+ + WG N GQL R
Sbjct: 177 SLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQLALSGR 218
Score = 66.1 bits (154), Expect = 6e-10
Identities = 49/149 (32%), Positives = 70/149 (46%), Gaps = 12/149 (8%)
Query: 350 RVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
++I V+CG +H+L L+++ ++S G N+ GQL RVR G
Sbjct: 129 KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQ--------RVRSLEG 180
Query: 409 APLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG--NIDDQWT-PQLVTKFLGRKVQS 465
PL VAAG HS A+ G WG GQL L N+ Q P V V
Sbjct: 181 IPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVY 240
Query: 466 VGCGACHSVLLTRGGELWACGASVFGQLG 494
+ CG H+ +LT+ G+++ G + GQLG
Sbjct: 241 ISCGDAHTAVLTQDGKVFTFGDNRSGQLG 269
Score = 38.7 bits (86), Expect = 0.10
Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 585 ISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRT 630
+S G HS + + G ++ WG +GQLG G+ K+I T KI T
Sbjct: 80 VSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISF-TPKKIMT 124
Score = 36.3 bits (80), Expect = 0.54
Identities = 32/117 (27%), Positives = 48/117 (41%), Gaps = 8/117 (6%)
Query: 354 VACGRHHTLILTENGL-YSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLV 412
VA G H+ L+ G + G N+ GQL L V +V
Sbjct: 186 VAAGGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKP------LSVGALKNLGVV 239
Query: 413 CVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCG 469
++ G H+A + G++ T+G GQLG ++ PQLV + G V + CG
Sbjct: 240 YISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDG-LVSQIDCG 295
>AY653202-1|AAV66896.1| 364|Homo sapiens truncated HERC6 protein.
Length = 364
Score = 93.1 bits (221), Expect = 4e-18
Identities = 77/268 (28%), Positives = 120/268 (44%), Gaps = 28/268 (10%)
Query: 351 VIDVACG-RHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
++ A G RH L+LT + + S GDN+ GQL ++
Sbjct: 25 LLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETLI-------- 76
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDD-QWTPQLVTKFLGRKVQSVGC 468
+ V+ G HS AV GR+ WG G GQLG+G + +TP+ + K+ V C
Sbjct: 77 -VDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSC 135
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQR-GKASLPVRVALHE--PVRALAAGYFHNLA 525
G HS+ L++ ++++ G + GQLG G+ + P RV E P+ +AAG H+ A
Sbjct: 136 GHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFA 195
Query: 526 LTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQI 585
L+ G + WG++ S +P + P V G +V I
Sbjct: 196 LSLCGTSFGWGSN--------SAGQLALSGRNVPVQSNK-----PLSVGALKNLG-VVYI 241
Query: 586 SAGWHHSCIINNMGSIYTWGLNFDGQLG 613
S G H+ ++ G ++T+G N GQLG
Sbjct: 242 SCGDAHTAVLTQDGKVFTFGDNRSGQLG 269
Score = 74.5 bits (175), Expect = 2e-12
Identities = 61/196 (31%), Positives = 88/196 (44%), Gaps = 14/196 (7%)
Query: 350 RVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
++I V+CG +H+L L+++ ++S G N+ GQL RVR G
Sbjct: 129 KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQ--------RVRSLEG 180
Query: 409 APLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG--NIDDQWT-PQLVTKFLGRKVQS 465
PL VAAG HS A+ G WG GQL L N+ Q P V V
Sbjct: 181 IPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVY 240
Query: 466 VGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV-ALHEPVRALAAGYFHNL 524
+ CG H+ +LT+ G+++ G + GQLG + P V + V + G +H L
Sbjct: 241 ISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGLVSQIDCGSYHTL 300
Query: 525 ALTH-KGEVYVWGASP 539
A H G+V +G P
Sbjct: 301 AYVHTTGQVVSFGHGP 316
Score = 69.3 bits (162), Expect = 6e-11
Identities = 62/222 (27%), Positives = 99/222 (44%), Gaps = 23/222 (10%)
Query: 402 RVRLAG--GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFL 459
R R AG GA L+ A+G HS + R+L+ G GQLG P+ +
Sbjct: 14 RRRTAGSPGAELLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALE 73
Query: 460 GRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASL-PVRVALHEPVRAL-- 516
V V CG HS+ + G ++A GA GQLG G+ + S P ++ ++ +
Sbjct: 74 TLIVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQV 133
Query: 517 AAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTT 576
+ G++H+LAL+ +V+ WG + S L + +P V
Sbjct: 134 SCGHYHSLALSKDSQVFSWGKN---------------SHGQLGLGKEFPSQASPQRV--R 176
Query: 577 NVRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDR 617
++ G + Q++AG HS ++ G+ + WG N GQL R
Sbjct: 177 SLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQLALSGR 218
Score = 38.7 bits (86), Expect = 0.10
Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 585 ISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRT 630
+S G HS + + G ++ WG +GQLG G+ K+I T KI T
Sbjct: 80 VSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISF-TPKKIMT 124
>AY653201-1|AAV66895.1| 986|Homo sapiens HERC6 splice variant
protein.
Length = 986
Score = 93.1 bits (221), Expect = 4e-18
Identities = 77/268 (28%), Positives = 120/268 (44%), Gaps = 28/268 (10%)
Query: 351 VIDVACG-RHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
++ A G RH L+LT + + S GDN+ GQL ++
Sbjct: 25 LLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETLI-------- 76
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDD-QWTPQLVTKFLGRKVQSVGC 468
+ V+ G HS AV GR+ WG G GQLG+G + +TP+ + K+ V C
Sbjct: 77 -VDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSC 135
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQR-GKASLPVRVALHE--PVRALAAGYFHNLA 525
G HS+ L++ ++++ G + GQLG G+ + P RV E P+ +AAG H+ A
Sbjct: 136 GHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFA 195
Query: 526 LTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQI 585
L+ G + WG++ S +P + P V G +V I
Sbjct: 196 LSLCGTSFGWGSN--------SAGQLALSGRNVPVQSNK-----PLSVGALKNLG-VVYI 241
Query: 586 SAGWHHSCIINNMGSIYTWGLNFDGQLG 613
S G H+ ++ G ++T+G N GQLG
Sbjct: 242 SCGDAHTAVLTQDGKVFTFGDNRSGQLG 269
Score = 74.5 bits (175), Expect = 2e-12
Identities = 61/196 (31%), Positives = 88/196 (44%), Gaps = 14/196 (7%)
Query: 350 RVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
++I V+CG +H+L L+++ ++S G N+ GQL RVR G
Sbjct: 129 KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQ--------RVRSLEG 180
Query: 409 APLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG--NIDDQWT-PQLVTKFLGRKVQS 465
PL VAAG HS A+ G WG GQL L N+ Q P V V
Sbjct: 181 IPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVY 240
Query: 466 VGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV-ALHEPVRALAAGYFHNL 524
+ CG H+ +LT+ G+++ G + GQLG + P V + V + G +H L
Sbjct: 241 ISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGLVSQIDCGSYHTL 300
Query: 525 ALTH-KGEVYVWGASP 539
A H G+V +G P
Sbjct: 301 AYVHTTGQVVSFGHGP 316
Score = 69.3 bits (162), Expect = 6e-11
Identities = 62/222 (27%), Positives = 99/222 (44%), Gaps = 23/222 (10%)
Query: 402 RVRLAG--GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFL 459
R R AG GA L+ A+G HS + R+L+ G GQLG P+ +
Sbjct: 14 RRRTAGSPGAELLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALE 73
Query: 460 GRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASL-PVRVALHEPVRAL-- 516
V V CG HS+ + G ++A GA GQLG G+ + S P ++ ++ +
Sbjct: 74 TLIVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQV 133
Query: 517 AAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTT 576
+ G++H+LAL+ +V+ WG + S L + +P V
Sbjct: 134 SCGHYHSLALSKDSQVFSWGKN---------------SHGQLGLGKEFPSQASPQRV--R 176
Query: 577 NVRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDR 617
++ G + Q++AG HS ++ G+ + WG N GQL R
Sbjct: 177 SLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQLALSGR 218
Score = 38.7 bits (86), Expect = 0.10
Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 585 ISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRT 630
+S G HS + + G ++ WG +GQLG G+ K+I T KI T
Sbjct: 80 VSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISF-TPKKIMT 124
>AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein.
Length = 1022
Score = 93.1 bits (221), Expect = 4e-18
Identities = 77/268 (28%), Positives = 120/268 (44%), Gaps = 28/268 (10%)
Query: 351 VIDVACG-RHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
++ A G RH L+LT + + S GDN+ GQL ++
Sbjct: 25 LLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETLI-------- 76
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDD-QWTPQLVTKFLGRKVQSVGC 468
+ V+ G HS AV GR+ WG G GQLG+G + +TP+ + K+ V C
Sbjct: 77 -VDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSC 135
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQR-GKASLPVRVALHE--PVRALAAGYFHNLA 525
G HS+ L++ ++++ G + GQLG G+ + P RV E P+ +AAG H+ A
Sbjct: 136 GHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFA 195
Query: 526 LTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQI 585
L+ G + WG++ S +P + P V G +V I
Sbjct: 196 LSLCGTSFGWGSN--------SAGQLALSGRNVPVQSNK-----PLSVGALKNLG-VVYI 241
Query: 586 SAGWHHSCIINNMGSIYTWGLNFDGQLG 613
S G H+ ++ G ++T+G N GQLG
Sbjct: 242 SCGDAHTAVLTQDGKVFTFGDNRSGQLG 269
Score = 74.5 bits (175), Expect = 2e-12
Identities = 61/196 (31%), Positives = 88/196 (44%), Gaps = 14/196 (7%)
Query: 350 RVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
++I V+CG +H+L L+++ ++S G N+ GQL RVR G
Sbjct: 129 KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQ--------RVRSLEG 180
Query: 409 APLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG--NIDDQWT-PQLVTKFLGRKVQS 465
PL VAAG HS A+ G WG GQL L N+ Q P V V
Sbjct: 181 IPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVY 240
Query: 466 VGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV-ALHEPVRALAAGYFHNL 524
+ CG H+ +LT+ G+++ G + GQLG + P V + V + G +H L
Sbjct: 241 ISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGLVSQIDCGSYHTL 300
Query: 525 ALTH-KGEVYVWGASP 539
A H G+V +G P
Sbjct: 301 AYVHTTGQVVSFGHGP 316
Score = 69.3 bits (162), Expect = 6e-11
Identities = 62/222 (27%), Positives = 99/222 (44%), Gaps = 23/222 (10%)
Query: 402 RVRLAG--GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFL 459
R R AG GA L+ A+G HS + R+L+ G GQLG P+ +
Sbjct: 14 RRRTAGSPGAELLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALE 73
Query: 460 GRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASL-PVRVALHEPVRAL-- 516
V V CG HS+ + G ++A GA GQLG G+ + S P ++ ++ +
Sbjct: 74 TLIVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQV 133
Query: 517 AAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTT 576
+ G++H+LAL+ +V+ WG + S L + +P V
Sbjct: 134 SCGHYHSLALSKDSQVFSWGKN---------------SHGQLGLGKEFPSQASPQRV--R 176
Query: 577 NVRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDR 617
++ G + Q++AG HS ++ G+ + WG N GQL R
Sbjct: 177 SLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQLALSGR 218
Score = 38.7 bits (86), Expect = 0.10
Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 585 ISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRT 630
+S G HS + + G ++ WG +GQLG G+ K+I T KI T
Sbjct: 80 VSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISF-TPKKIMT 124
>AB046813-1|BAB13419.1| 953|Homo sapiens KIAA1593 protein protein.
Length = 953
Score = 93.1 bits (221), Expect = 4e-18
Identities = 68/222 (30%), Positives = 100/222 (45%), Gaps = 23/222 (10%)
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLGRKVQSVGCG 469
+V VA G+YHS A+ + WG +GQLGLG + Q +PQL+ LG V G
Sbjct: 35 IVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAG 94
Query: 470 ACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLALT 527
HS +LT G ++ G + FGQLG +P ++ + + + G H ALT
Sbjct: 95 GAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALT 154
Query: 528 HKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIV-QIS 586
+G V+ +GA H+ N R + G IV +I+
Sbjct: 155 KEGGVFTFGAGGYGQLGHNSTS-----------HEINPR-------KVFELMGSIVTEIA 196
Query: 587 AGWHH-SCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
G H S + + G IY++GL +GQLG+G + P VK
Sbjct: 197 CGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVK 238
Score = 83.0 bits (196), Expect = 5e-15
Identities = 56/191 (29%), Positives = 91/191 (47%), Gaps = 12/191 (6%)
Query: 350 RVIDVACGRHHTLILTE-NGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
+++ VACG +H+L L++ + ++ G N +GQL +L+ L G
Sbjct: 34 QIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQ------LLKSLL--G 85
Query: 409 APLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGC 468
P + VAAG HS + G + WG GQLGL + +D++ P L+ +K+ + C
Sbjct: 86 IPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICC 145
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV--ALHEPVRALAAGYFHNLA- 525
G H+ LT+ G ++ GA +GQLG P +V + V +A G H A
Sbjct: 146 GEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQHTSAF 205
Query: 526 LTHKGEVYVWG 536
+ G +Y +G
Sbjct: 206 VPSSGRIYSFG 216
Score = 44.0 bits (99), Expect = 0.003
Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 11/105 (10%)
Query: 350 RVIDVACGRHHTLILT-ENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
+++ + CG HT LT E G+++ G +GQL +V G
Sbjct: 139 KIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPR---------KVFELMG 189
Query: 409 APLVCVAAGHYH-SAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP 452
+ + +A G H SA V + GR+ ++G G +GQLG G+ ++ +P
Sbjct: 190 SIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSP 234
Score = 38.7 bits (86), Expect = 0.10
Identities = 18/48 (37%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSG-DRKQIQIPTEVK 627
+IVQ++ G++HS ++ ++ WG N GQLG G D K+ P +K
Sbjct: 34 QIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLK 81
>BC065375-1|AAH65375.1| 458|Homo sapiens secretion regulating
guanine nucleotide exchange factor protein.
Length = 458
Score = 92.3 bits (219), Expect = 8e-18
Identities = 70/219 (31%), Positives = 102/219 (46%), Gaps = 19/219 (8%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDD--QWTPQLVTKFLGRKVQSVGCGAC 471
+ G HSA V GG L G GQLGLG+ +D +TP G +Q V CG
Sbjct: 54 ITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEDIPYFTP--CKSLFGCPIQQVACGWD 111
Query: 472 HSVLLTRGGELWACGASVFGQLGT--GQRGKASLPVRVALH-EPVRALAAGYFHNLALTH 528
+++LT G++ +CG++ FGQLG G R + +P + LH E V +AAG H +A T
Sbjct: 112 FTIMLTENGQVLSCGSNSFGQLGVPHGPR-RCVVPQAIELHKEKVVCIAAGLRHAVAATA 170
Query: 529 KGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAG 588
G V+ WG TLP PS V T + + + AG
Sbjct: 171 SGIVFQWGTGLASCGRRLC------PGQTLPLFFTAKE---PSRV-TGLENSKAMCVLAG 220
Query: 589 WHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
HS + + G +Y WG N GQL + + + +P +++
Sbjct: 221 SDHSASLTDAGEVYVWGSNKHGQL-ANEAAFLPVPQKIE 258
Score = 82.2 bits (194), Expect = 8e-15
Identities = 85/324 (26%), Positives = 127/324 (39%), Gaps = 34/324 (10%)
Query: 321 CGLAHWAVVSDGNARVMMASTPVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQ 379
CGL + G+ + TP + + VACG T++LTENG + S G N+FGQ
Sbjct: 73 CGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQ 132
Query: 380 LXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHG 439
L +VC+AAG H+ A A G + WG G+
Sbjct: 133 LGVPHGPRRCVVPQAIELHK---------EKVVCIAAGLRHAVAATASGIVFQWGTGLAS 183
Query: 440 ---QLGLGNIDDQW----TPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQ 492
+L G + P VT K V G+ HS LT GE++ G++ GQ
Sbjct: 184 CGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQ 243
Query: 493 LGTGQRGKASLPVRVALH----EPVRALAAGYFHNLALTHKGEVYVWGASPQ----QVXX 544
L + +P ++ H E V A+ +G+ H +A T G+++ WG + +
Sbjct: 244 L-ANEAAFLPVPQKIEAHCFQNEKVTAIWSGWTHLVAQTETGKMFTWGRADYGQLGRKLE 302
Query: 545 XXXXXXXEPSSPTLP-FHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYT 603
E LP N +P C+ ++S G H+ I G Y+
Sbjct: 303 TYEGWKLEKQDSFLPCSRPPNSMPSSPHCLTGA------TEVSCGSEHNLAIIG-GVCYS 355
Query: 604 WGLNFDGQLGSGDRKQIQIPTEVK 627
WG N G G G + P V+
Sbjct: 356 WGWNEHGMCGDGTEANVWAPKPVQ 379
Score = 78.2 bits (184), Expect = 1e-13
Identities = 75/273 (27%), Positives = 116/273 (42%), Gaps = 38/273 (13%)
Query: 421 SAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLG-RKVQSVGCGACHSVLLTRG 479
S A A L WG +GQLGLG+ +D PQ + F R V+ + G HS ++T G
Sbjct: 8 SEAAPAAAALFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDG 67
Query: 480 GELWACGASVFGQLGTGQRGKAS--LPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGA 537
G+L+ CG + GQLG G P + P++ +A G+ + LT G+V G+
Sbjct: 68 GDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIMLTENGQVLSCGS 127
Query: 538 SPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINN 597
+ P P R + P ++ + ++V I+AG H+
Sbjct: 128 N-------SFGQLGVPHGPR--------RCVVPQAIELH--KEKVVCIAAGLRHAVAATA 170
Query: 598 MGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMKSDSEKTTDADENMEFNTKA 657
G ++ WG L S R+ T T +P + T + N+KA
Sbjct: 171 SGIVFQWGTG----LASCGRRLCPGQTLPLFFTAKEP-------SRVTGLE-----NSKA 214
Query: 658 L-VGCGGDFTVYIDDDGRIYSTG-NTHLQISNE 688
+ V G D + + D G +Y G N H Q++NE
Sbjct: 215 MCVLAGSDHSASLTDAGEVYVWGSNKHGQLANE 247
Score = 50.8 bits (116), Expect = 2e-05
Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 1/63 (1%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHS 473
V+ G H+ A+ GG +WGW HG G G + W P+ V L VGCGA HS
Sbjct: 338 VSCGSEHNLAI-IGGVCYSWGWNEHGMCGDGTEANVWAPKPVQALLSSSGLLVGCGAGHS 396
Query: 474 VLL 476
+ L
Sbjct: 397 LAL 399
>AJ243951-1|CAB60833.1| 288|Homo sapiens deafness locus associated
putative guanine nucleotide exchange factor protein.
Length = 288
Score = 92.3 bits (219), Expect = 8e-18
Identities = 70/219 (31%), Positives = 102/219 (46%), Gaps = 19/219 (8%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDD--QWTPQLVTKFLGRKVQSVGCGAC 471
+ G HSA V GG L G GQLGLG+ +D +TP G +Q V CG
Sbjct: 54 ITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEDIPYFTP--CKSLFGCPIQQVACGWD 111
Query: 472 HSVLLTRGGELWACGASVFGQLGT--GQRGKASLPVRVALH-EPVRALAAGYFHNLALTH 528
+++LT G++ +CG++ FGQLG G R + +P + LH E V +AAG H +A T
Sbjct: 112 FTIMLTENGQVLSCGSNSFGQLGVPHGPR-RCVVPQAIELHKEKVVCIAAGLRHAVAATA 170
Query: 529 KGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAG 588
G V+ WG TLP PS V T + + + AG
Sbjct: 171 SGIVFQWGTGLASCGRRLC------PGQTLPLFFTAKE---PSRV-TGLENSKAMCVLAG 220
Query: 589 WHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
HS + + G +Y WG N GQL + + + +P +++
Sbjct: 221 SDHSASLTDAGEVYVWGSNKHGQL-ANEAAFLPVPQKIE 258
Score = 78.2 bits (184), Expect = 1e-13
Identities = 75/273 (27%), Positives = 116/273 (42%), Gaps = 38/273 (13%)
Query: 421 SAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLG-RKVQSVGCGACHSVLLTRG 479
S A A L WG +GQLGLG+ +D PQ + F R V+ + G HS ++T G
Sbjct: 8 SEAAPAAAALFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDG 67
Query: 480 GELWACGASVFGQLGTGQRGKAS--LPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGA 537
G+L+ CG + GQLG G P + P++ +A G+ + LT G+V G+
Sbjct: 68 GDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIMLTENGQVLSCGS 127
Query: 538 SPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINN 597
+ P P R + P ++ + ++V I+AG H+
Sbjct: 128 N-------SFGQLGVPHGPR--------RCVVPQAIELH--KEKVVCIAAGLRHAVAATA 170
Query: 598 MGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMKSDSEKTTDADENMEFNTKA 657
G ++ WG L S R+ T T +P + T + N+KA
Sbjct: 171 SGIVFQWGTG----LASCGRRLCPGQTLPLFFTAKEP-------SRVTGLE-----NSKA 214
Query: 658 L-VGCGGDFTVYIDDDGRIYSTG-NTHLQISNE 688
+ V G D + + D G +Y G N H Q++NE
Sbjct: 215 MCVLAGSDHSASLTDAGEVYVWGSNKHGQLANE 247
Score = 62.1 bits (144), Expect = 1e-08
Identities = 62/219 (28%), Positives = 91/219 (41%), Gaps = 22/219 (10%)
Query: 321 CGLAHWAVVSDGNARVMMASTPVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQ 379
CGL + G+ + TP + + VACG T++LTENG + S G N+FGQ
Sbjct: 73 CGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQ 132
Query: 380 LXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHG 439
L +VC+AAG H+ A A G + WG G+
Sbjct: 133 LGVPHGPRRCVVPQAIELHK---------EKVVCIAAGLRHAVAATASGIVFQWGTGLAS 183
Query: 440 ---QLGLGNIDDQW----TPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQ 492
+L G + P VT K V G+ HS LT GE++ G++ GQ
Sbjct: 184 CGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQ 243
Query: 493 LGTGQRGKASLPVRVALH----EPVRALAAGYFHNLALT 527
L + +P ++ H E V A+ +G+ H +A T
Sbjct: 244 L-ANEAAFLPVPQKIEAHCFQNEKVTAIWSGWTHLVAQT 281
Score = 50.0 bits (114), Expect = 4e-05
Identities = 43/140 (30%), Positives = 64/140 (45%), Gaps = 9/140 (6%)
Query: 408 GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVG 467
G P+ VA G + + G++L+ G GQLG+ + + + KV +
Sbjct: 100 GCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVCIA 159
Query: 468 CGACHSVLLTRGGEL--WACGASVFGQ-LGTGQR----GKASLPVRVALHEPVRALA--A 518
G H+V T G + W G + G+ L GQ A P RV E +A+ A
Sbjct: 160 AGLRHAVAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLA 219
Query: 519 GYFHNLALTHKGEVYVWGAS 538
G H+ +LT GEVYVWG++
Sbjct: 220 GSDHSASLTDAGEVYVWGSN 239
Score = 37.1 bits (82), Expect = 0.31
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 5/74 (6%)
Query: 412 VCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTK--FLGRKVQSVGCG 469
+CV AG HSA++ G + WG HGQL PQ + F KV ++ G
Sbjct: 215 MCVLAGSDHSASLTDAGEVYVWGSNKHGQLA-NEAAFLPVPQKIEAHCFQNEKVTAIWSG 273
Query: 470 ACHSVLLTRGGELW 483
H L+ + G LW
Sbjct: 274 WTH--LVAQTGLLW 285
>AJ243950-1|CAB60832.1| 458|Homo sapiens deafness locus associated
putative guanine nucleotide exchange factor protein.
Length = 458
Score = 92.3 bits (219), Expect = 8e-18
Identities = 70/219 (31%), Positives = 102/219 (46%), Gaps = 19/219 (8%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDD--QWTPQLVTKFLGRKVQSVGCGAC 471
+ G HSA V GG L G GQLGLG+ +D +TP G +Q V CG
Sbjct: 54 ITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEDIPYFTP--CKSLFGCPIQQVACGWD 111
Query: 472 HSVLLTRGGELWACGASVFGQLGT--GQRGKASLPVRVALH-EPVRALAAGYFHNLALTH 528
+++LT G++ +CG++ FGQLG G R + +P + LH E V +AAG H +A T
Sbjct: 112 FTIMLTENGQVLSCGSNSFGQLGVPHGPR-RCVVPQAIELHKEKVVCIAAGLRHAVAATA 170
Query: 529 KGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAG 588
G V+ WG TLP PS V T + + + AG
Sbjct: 171 SGIVFQWGTGLASCGRRLC------PGQTLPLFFTAKE---PSRV-TGLENSKAMCVLAG 220
Query: 589 WHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
HS + + G +Y WG N GQL + + + +P +++
Sbjct: 221 SDHSASLTDAGEVYVWGSNKHGQL-ANEAAFLPVPQKIE 258
Score = 82.2 bits (194), Expect = 8e-15
Identities = 85/324 (26%), Positives = 127/324 (39%), Gaps = 34/324 (10%)
Query: 321 CGLAHWAVVSDGNARVMMASTPVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQ 379
CGL + G+ + TP + + VACG T++LTENG + S G N+FGQ
Sbjct: 73 CGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQ 132
Query: 380 LXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHG 439
L +VC+AAG H+ A A G + WG G+
Sbjct: 133 LGVPHGPRRCVVPQAIELHK---------EKVVCIAAGLRHAVAATASGIVFQWGTGLAS 183
Query: 440 ---QLGLGNIDDQW----TPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQ 492
+L G + P VT K V G+ HS LT GE++ G++ GQ
Sbjct: 184 CGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQ 243
Query: 493 LGTGQRGKASLPVRVALH----EPVRALAAGYFHNLALTHKGEVYVWGASPQ----QVXX 544
L + +P ++ H E V A+ +G+ H +A T G+++ WG + +
Sbjct: 244 L-ANEAAFLPVPQKIEAHCFQNEKVTAIWSGWTHLVAQTETGKMFTWGRADYGQLGRKLE 302
Query: 545 XXXXXXXEPSSPTLP-FHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYT 603
E LP N +P C+ ++S G H+ I G Y+
Sbjct: 303 TYEGWKLEKQDSFLPCSRPPNSMPSSPHCLTGA------TEVSCGSEHNLAIIG-GVCYS 355
Query: 604 WGLNFDGQLGSGDRKQIQIPTEVK 627
WG N G G G + P V+
Sbjct: 356 WGWNEHGMCGDGTEANVWAPKPVQ 379
Score = 78.2 bits (184), Expect = 1e-13
Identities = 75/273 (27%), Positives = 116/273 (42%), Gaps = 38/273 (13%)
Query: 421 SAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLG-RKVQSVGCGACHSVLLTRG 479
S A A L WG +GQLGLG+ +D PQ + F R V+ + G HS ++T G
Sbjct: 8 SEAAPAAAALFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDG 67
Query: 480 GELWACGASVFGQLGTGQRGKAS--LPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGA 537
G+L+ CG + GQLG G P + P++ +A G+ + LT G+V G+
Sbjct: 68 GDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIMLTENGQVLSCGS 127
Query: 538 SPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINN 597
+ P P R + P ++ + ++V I+AG H+
Sbjct: 128 N-------SFGQLGVPHGPR--------RCVVPQAIELH--KEKVVCIAAGLRHAVAATA 170
Query: 598 MGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMKSDSEKTTDADENMEFNTKA 657
G ++ WG L S R+ T T +P + T + N+KA
Sbjct: 171 SGIVFQWGTG----LASCGRRLCPGQTLPLFFTAKEP-------SRVTGLE-----NSKA 214
Query: 658 L-VGCGGDFTVYIDDDGRIYSTG-NTHLQISNE 688
+ V G D + + D G +Y G N H Q++NE
Sbjct: 215 MCVLAGSDHSASLTDAGEVYVWGSNKHGQLANE 247
Score = 50.8 bits (116), Expect = 2e-05
Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 1/63 (1%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHS 473
V+ G H+ A+ GG +WGW HG G G + W P+ V L VGCGA HS
Sbjct: 338 VSCGSEHNLAI-IGGVCYSWGWNEHGMCGDGTEANVWAPKPVQALLSSSGLLVGCGAGHS 396
Query: 474 VLL 476
+ L
Sbjct: 397 LAL 399
>BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 8 protein.
Length = 692
Score = 87.8 bits (208), Expect = 2e-16
Identities = 73/275 (26%), Positives = 120/275 (43%), Gaps = 29/275 (10%)
Query: 408 GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVG 467
G + VA G + +A + G ++T+G G +G LG G++ D P +V LG ++ V
Sbjct: 390 GVTIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVA 449
Query: 468 CGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVAL--HEPVRALAAGYFHNLA 525
CGA H + L+ EL+A G G+LG G R S P +V + + + + G ++
Sbjct: 450 CGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVCGIDSSMI 509
Query: 526 LTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNV-RGRIVQ 584
LT G+ G++ E P H + L+ + + + + + ++
Sbjct: 510 LTVPGQALACGSNRFNKLGLDHLSLGEEPVP----HQQVEEALSFTLLGSAPLDQEPLLS 565
Query: 585 ISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMKSDSEKT 644
I G HS + G YT+G N GQLG+ R+ + P +V
Sbjct: 566 IDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCKV------------------ 607
Query: 645 TDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTG 679
+ +E A+V CG FTV I + +YS G
Sbjct: 608 ----QGLEGIKMAMVACGDAFTVAIGAESEVYSWG 638
Score = 70.9 bits (166), Expect = 2e-11
Identities = 80/305 (26%), Positives = 124/305 (40%), Gaps = 45/305 (14%)
Query: 354 VACGRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVC 413
VACG T LT+ G+ TFG ++ L G +V
Sbjct: 396 VACGDFFTACLTDRGIIM----TFG--SGSNGCLGHGSLTDISQPTIVEALL--GYEMVQ 447
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHS 473
VA G H A+ L WG G G+LGLG + PQ V G++ Q V CG S
Sbjct: 448 VACGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVCGIDSS 507
Query: 474 VLLTRGGELWACGASVFGQLGTG--QRGKASLP---VRVAL-----------HEPVRALA 517
++LT G+ ACG++ F +LG G+ +P V AL EP+ ++
Sbjct: 508 MILTVPGQALACGSNRFNKLGLDHLSLGEEPVPHQQVEEALSFTLLGSAPLDQEPLLSID 567
Query: 518 AGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTN 577
G H+ A+T G+ Y +G++ N R + +
Sbjct: 568 LGTAHSAAVTASGDCYTFGSNQHGQLGT------------------NTRRGSRAPCKVQG 609
Query: 578 VRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHT 636
+ G ++ ++ G + I +Y+WG G+LG D + +P V++ ET P+T
Sbjct: 610 LEGIKMAMVACGDAFTVAIGAESEVYSWGKGARGRLGRRD-EDAGLPRPVQL-DETHPYT 667
Query: 637 MKSDS 641
+ S S
Sbjct: 668 VTSVS 672
Score = 55.2 bits (127), Expect = 1e-06
Identities = 44/135 (32%), Positives = 61/135 (45%), Gaps = 9/135 (6%)
Query: 411 LVCVAAGHYHSAAVDAGGRLLTW---GWGVHGQLGLGNIDDQWTPQLVTKFL----GRKV 463
+V VAAG A V GRL+ W G G L +Q PQ +++FL G +
Sbjct: 334 VVQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTI 393
Query: 464 QSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYF 521
+ V CG + LT G + G+ G LG G S P V L + +A G
Sbjct: 394 KHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGAS 453
Query: 522 HNLALTHKGEVYVWG 536
H LAL+ + E++ WG
Sbjct: 454 HVLALSTERELFAWG 468
>BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8
protein.
Length = 692
Score = 87.8 bits (208), Expect = 2e-16
Identities = 73/275 (26%), Positives = 120/275 (43%), Gaps = 29/275 (10%)
Query: 408 GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVG 467
G + VA G + +A + G ++T+G G +G LG G++ D P +V LG ++ V
Sbjct: 390 GVTIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVA 449
Query: 468 CGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVAL--HEPVRALAAGYFHNLA 525
CGA H + L+ EL+A G G+LG G R S P +V + + + + G ++
Sbjct: 450 CGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVCGIDSSMI 509
Query: 526 LTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNV-RGRIVQ 584
LT G+ G++ E P H + L+ + + + + + ++
Sbjct: 510 LTVPGQALACGSNRFNKLGLDHLSLGEEPVP----HQQVEEALSFTLLGSAPLDQEPLLS 565
Query: 585 ISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMKSDSEKT 644
I G HS + G YT+G N GQLG+ R+ + P +V
Sbjct: 566 IDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCKV------------------ 607
Query: 645 TDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTG 679
+ +E A+V CG FTV I + +YS G
Sbjct: 608 ----QGLEGIKMAMVACGDAFTVAIGAESEVYSWG 638
Score = 70.9 bits (166), Expect = 2e-11
Identities = 80/305 (26%), Positives = 124/305 (40%), Gaps = 45/305 (14%)
Query: 354 VACGRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVC 413
VACG T LT+ G+ TFG ++ L G +V
Sbjct: 396 VACGDFFTACLTDRGIIM----TFG--SGSNGCLGHGSLTDISQPTIVEALL--GYEMVQ 447
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHS 473
VA G H A+ L WG G G+LGLG + PQ V G++ Q V CG S
Sbjct: 448 VACGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVCGIDSS 507
Query: 474 VLLTRGGELWACGASVFGQLGTG--QRGKASLP---VRVAL-----------HEPVRALA 517
++LT G+ ACG++ F +LG G+ +P V AL EP+ ++
Sbjct: 508 MILTVPGQALACGSNRFNKLGLDHLSLGEEPVPHQQVEEALSFTLLGSAPLDQEPLLSID 567
Query: 518 AGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTN 577
G H+ A+T G+ Y +G++ N R + +
Sbjct: 568 LGTAHSAAVTASGDCYTFGSNQHGQLGT------------------NTRRGSRAPCKVQG 609
Query: 578 VRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHT 636
+ G ++ ++ G + I +Y+WG G+LG D + +P V++ ET P+T
Sbjct: 610 LEGIKMAMVACGDAFTVAIGAESEVYSWGKGARGRLGRRD-EDAGLPRPVQL-DETHPYT 667
Query: 637 MKSDS 641
+ S S
Sbjct: 668 VTSVS 672
Score = 55.2 bits (127), Expect = 1e-06
Identities = 44/135 (32%), Positives = 61/135 (45%), Gaps = 9/135 (6%)
Query: 411 LVCVAAGHYHSAAVDAGGRLLTW---GWGVHGQLGLGNIDDQWTPQLVTKFL----GRKV 463
+V VAAG A V GRL+ W G G L +Q PQ +++FL G +
Sbjct: 334 VVQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTI 393
Query: 464 QSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYF 521
+ V CG + LT G + G+ G LG G S P V L + +A G
Sbjct: 394 KHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGAS 453
Query: 522 HNLALTHKGEVYVWG 536
H LAL+ + E++ WG
Sbjct: 454 HVLALSTERELFAWG 468
>AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8
protein.
Length = 692
Score = 87.8 bits (208), Expect = 2e-16
Identities = 73/275 (26%), Positives = 120/275 (43%), Gaps = 29/275 (10%)
Query: 408 GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVG 467
G + VA G + +A + G ++T+G G +G LG G++ D P +V LG ++ V
Sbjct: 390 GVTIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVA 449
Query: 468 CGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVAL--HEPVRALAAGYFHNLA 525
CGA H + L+ EL+A G G+LG G R S P +V + + + + G ++
Sbjct: 450 CGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVCGIDSSMI 509
Query: 526 LTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNV-RGRIVQ 584
LT G+ G++ E P H + L+ + + + + + ++
Sbjct: 510 LTVPGQALACGSNRFNKLGLDHLSLGEEPVP----HQQVEEALSFTLLGSAPLDQEPLLS 565
Query: 585 ISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMKSDSEKT 644
I G HS + G YT+G N GQLG+ R+ + P +V
Sbjct: 566 IDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCKV------------------ 607
Query: 645 TDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTG 679
+ +E A+V CG FTV I + +YS G
Sbjct: 608 ----QGLEGIKMAMVACGDAFTVAIGAESEVYSWG 638
Score = 70.9 bits (166), Expect = 2e-11
Identities = 80/305 (26%), Positives = 124/305 (40%), Gaps = 45/305 (14%)
Query: 354 VACGRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVC 413
VACG T LT+ G+ TFG ++ L G +V
Sbjct: 396 VACGDFFTACLTDRGIIM----TFG--SGSNGCLGHGSLTDISQPTIVEALL--GYEMVQ 447
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHS 473
VA G H A+ L WG G G+LGLG + PQ V G++ Q V CG S
Sbjct: 448 VACGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVCGIDSS 507
Query: 474 VLLTRGGELWACGASVFGQLGTG--QRGKASLP---VRVAL-----------HEPVRALA 517
++LT G+ ACG++ F +LG G+ +P V AL EP+ ++
Sbjct: 508 MILTVPGQALACGSNRFNKLGLDHLSLGEEPVPHQQVEEALSFTLLGSAPLDQEPLLSID 567
Query: 518 AGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTN 577
G H+ A+T G+ Y +G++ N R + +
Sbjct: 568 LGTAHSAAVTASGDCYTFGSNQHGQLGT------------------NTRRGSRAPCKVQG 609
Query: 578 VRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHT 636
+ G ++ ++ G + I +Y+WG G+LG D + +P V++ ET P+T
Sbjct: 610 LEGIKMAMVACGDAFTVAIGAESEVYSWGKGARGRLGRRD-EDAGLPRPVQL-DETHPYT 667
Query: 637 MKSDS 641
+ S S
Sbjct: 668 VTSVS 672
Score = 55.2 bits (127), Expect = 1e-06
Identities = 44/135 (32%), Positives = 61/135 (45%), Gaps = 9/135 (6%)
Query: 411 LVCVAAGHYHSAAVDAGGRLLTW---GWGVHGQLGLGNIDDQWTPQLVTKFL----GRKV 463
+V VAAG A V GRL+ W G G L +Q PQ +++FL G +
Sbjct: 334 VVQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTI 393
Query: 464 QSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYF 521
+ V CG + LT G + G+ G LG G S P V L + +A G
Sbjct: 394 KHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGAS 453
Query: 522 HNLALTHKGEVYVWG 536
H LAL+ + E++ WG
Sbjct: 454 HVLALSTERELFAWG 468
>AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a
protein.
Length = 692
Score = 87.8 bits (208), Expect = 2e-16
Identities = 73/275 (26%), Positives = 120/275 (43%), Gaps = 29/275 (10%)
Query: 408 GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVG 467
G + VA G + +A + G ++T+G G +G LG G++ D P +V LG ++ V
Sbjct: 390 GVTIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVA 449
Query: 468 CGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVAL--HEPVRALAAGYFHNLA 525
CGA H + L+ EL+A G G+LG G R S P +V + + + + G ++
Sbjct: 450 CGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVCGIDSSMI 509
Query: 526 LTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNV-RGRIVQ 584
LT G+ G++ E P H + L+ + + + + + ++
Sbjct: 510 LTVPGQALACGSNRFNKLGLDHLSLGEEPVP----HQQVEEALSFTLLGSAPLDQEPLLS 565
Query: 585 ISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMKSDSEKT 644
I G HS + G YT+G N GQLG+ R+ + P +V
Sbjct: 566 IDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCKV------------------ 607
Query: 645 TDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTG 679
+ +E A+V CG FTV I + +YS G
Sbjct: 608 ----QGLEGIKMAMVACGDAFTVAIGAESEVYSWG 638
Score = 70.9 bits (166), Expect = 2e-11
Identities = 80/305 (26%), Positives = 124/305 (40%), Gaps = 45/305 (14%)
Query: 354 VACGRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVC 413
VACG T LT+ G+ TFG ++ L G +V
Sbjct: 396 VACGDFFTACLTDRGIIM----TFG--SGSNGCLGHGSLTDISQPTIVEALL--GYEMVQ 447
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHS 473
VA G H A+ L WG G G+LGLG + PQ V G++ Q V CG S
Sbjct: 448 VACGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVCGIDSS 507
Query: 474 VLLTRGGELWACGASVFGQLGTG--QRGKASLP---VRVAL-----------HEPVRALA 517
++LT G+ ACG++ F +LG G+ +P V AL EP+ ++
Sbjct: 508 MILTVPGQALACGSNRFNKLGLDHLSLGEEPVPHQQVEEALSFTLLGSAPLDQEPLLSID 567
Query: 518 AGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTN 577
G H+ A+T G+ Y +G++ N R + +
Sbjct: 568 LGTAHSAAVTASGDCYTFGSNQHGQLGT------------------NTRRGSRAPCKVQG 609
Query: 578 VRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHT 636
+ G ++ ++ G + I +Y+WG G+LG D + +P V++ ET P+T
Sbjct: 610 LEGIKMAMVACGDAFTVAIGAESEVYSWGKGARGRLGRRD-EDAGLPRPVQL-DETHPYT 667
Query: 637 MKSDS 641
+ S S
Sbjct: 668 VTSVS 672
Score = 55.2 bits (127), Expect = 1e-06
Identities = 44/135 (32%), Positives = 61/135 (45%), Gaps = 9/135 (6%)
Query: 411 LVCVAAGHYHSAAVDAGGRLLTW---GWGVHGQLGLGNIDDQWTPQLVTKFL----GRKV 463
+V VAAG A V GRL+ W G G L +Q PQ +++FL G +
Sbjct: 334 VVQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTI 393
Query: 464 QSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYF 521
+ V CG + LT G + G+ G LG G S P V L + +A G
Sbjct: 394 KHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGAS 453
Query: 522 HNLALTHKGEVYVWG 536
H LAL+ + E++ WG
Sbjct: 454 HVLALSTERELFAWG 468
>AF224249-1|AAO27475.1| 328|Homo sapiens HERC2 protein.
Length = 328
Score = 79.0 bits (186), Expect = 8e-14
Identities = 55/190 (28%), Positives = 86/190 (45%), Gaps = 10/190 (5%)
Query: 350 RVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
R+ D+ACG H+ LT +G LY+ G +G+L +++V L
Sbjct: 138 RIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPK-------MVKVLLGHR 190
Query: 409 APLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGC 468
V + + A+ G + +WG G G+LG G + PQ + + G+ V + C
Sbjct: 191 VIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIEC 250
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLAL 526
GA S+ LT+ G +W G + +LG G P V + + +A G H LA+
Sbjct: 251 GAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAV 310
Query: 527 THKGEVYVWG 536
T G+VY WG
Sbjct: 311 TDSGQVYAWG 320
Score = 75.4 bits (177), Expect = 1e-12
Identities = 72/282 (25%), Positives = 114/282 (40%), Gaps = 28/282 (9%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
V+ VA G +T G +Y+ G+ T G+L V+
Sbjct: 32 VVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLGISSGTVPIPRQITALSSYVVKK---- 87
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCG 469
V V +G H+ A+ G++ WG G G+LG + + P+L+ ++++ + CG
Sbjct: 88 --VAVHSGGRHATALTVDGKVFWWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACG 145
Query: 470 ACHSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGY--FHNLA 525
+ HS LT GEL+ G +G+LG G P V+V L V +A G LA
Sbjct: 146 SSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLA 205
Query: 526 LTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQI 585
LT +G V+ WG E + P ++ N +G + QI
Sbjct: 206 LTDEGLVFSWGDGD---FGKLGRGGSEGCN-------------IPQNIERLNGQG-VCQI 248
Query: 586 SAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
G S + G ++TWG +LG G ++ P V+
Sbjct: 249 ECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVE 290
Score = 66.9 bits (156), Expect = 3e-10
Identities = 55/178 (30%), Positives = 79/178 (44%), Gaps = 12/178 (6%)
Query: 320 TCGLAHWAVVSDGNARVMMASTPVNTELIGRVIDVACGRH--HTLILTENGL-YSAGDNT 376
T GL + + G+ + V L RVI VACG TL LT+ GL +S GD
Sbjct: 160 TWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGD 219
Query: 377 FGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWG 436
FG+L + R+ G + C G S A+ G + TWG G
Sbjct: 220 FGKLGRGGSEGCNIPQN------IERLNGQGVCQIEC---GAQFSLALTKSGVVWTWGKG 270
Query: 437 VHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLG 494
+ +LG G+ PQ+V G+K+ V GA H + +T G+++A G + GQ G
Sbjct: 271 DYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQG 328
Score = 54.8 bits (126), Expect = 1e-06
Identities = 56/201 (27%), Positives = 83/201 (41%), Gaps = 24/201 (11%)
Query: 435 WGVHGQLGLGNIDDQW--TPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQ 492
WG++ + LG + P V V G+ +T G+++ACG + G+
Sbjct: 2 WGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEATNGR 61
Query: 493 LGTG-QRGKASLPVRV-ALHEPVR---ALAAGYFHNLALTHKGEVYVWGASPQQVXXXXX 547
LG G G +P ++ AL V A+ +G H ALT G+V+ WG
Sbjct: 62 LGLGISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFWWG----------- 110
Query: 548 XXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLN 607
E L H P ++ + RI I+ G HS + + G +YTWGL
Sbjct: 111 ----EGDDGKLG-HFSRMNCDKPRLIEALKTK-RIRDIACGSSHSAALTSSGELYTWGLG 164
Query: 608 FDGQLGSGDRKQIQIPTEVKI 628
G+LG GD P VK+
Sbjct: 165 EYGRLGHGDNTTQLKPKMVKV 185
>AL356741-1|CAH74146.1| 907|Homo sapiens hect domain and RLD 4
protein.
Length = 907
Score = 77.8 bits (183), Expect = 2e-13
Identities = 60/208 (28%), Positives = 91/208 (43%), Gaps = 23/208 (11%)
Query: 425 DAGGRLLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELW 483
++ + WG +GQLGLG + Q +PQL+ LG V G HS +LT G ++
Sbjct: 3 ESASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIF 62
Query: 484 ACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQ 541
G + FGQLG +P ++ + + + G H ALT +G V+ +GA
Sbjct: 63 GWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYG 122
Query: 542 VXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIV-QISAGWHH-SCIINNMG 599
H+ N R + G IV +I+ G H S + + G
Sbjct: 123 QLGHNSTS-----------HEINPR-------KVFELMGSIVTEIACGRQHTSAFVPSSG 164
Query: 600 SIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
IY++GL +GQLG+G + P VK
Sbjct: 165 RIYSFGLGGNGQLGTGSTSNRKSPFTVK 192
Score = 72.5 bits (170), Expect = 7e-12
Identities = 42/132 (31%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Query: 408 GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVG 467
G P + VAAG HS + G + WG GQLGL + +D++ P L+ +K+ +
Sbjct: 39 GIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYIC 98
Query: 468 CGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV--ALHEPVRALAAGYFHNLA 525
CG H+ LT+ G ++ GA +GQLG P +V + V +A G H A
Sbjct: 99 CGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQHTSA 158
Query: 526 -LTHKGEVYVWG 536
+ G +Y +G
Sbjct: 159 FVPSSGRIYSFG 170
Score = 62.9 bits (146), Expect = 5e-09
Identities = 46/158 (29%), Positives = 70/158 (44%), Gaps = 11/158 (6%)
Query: 352 IDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAP 410
+ VA G H+ +LT +G ++ G N FGQL LR +
Sbjct: 43 MQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKS----LRSQ-----K 93
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA 470
+V + G H+AA+ G + T+G G +GQLG + + P+ V + +G V + CG
Sbjct: 94 IVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGR 153
Query: 471 CH-SVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV 507
H S + G +++ G GQLGTG P V
Sbjct: 154 QHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTV 191
Score = 44.0 bits (99), Expect = 0.003
Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 11/105 (10%)
Query: 350 RVIDVACGRHHTLILT-ENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
+++ + CG HT LT E G+++ G +GQL +V G
Sbjct: 93 KIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPR---------KVFELMG 143
Query: 409 APLVCVAAGHYH-SAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP 452
+ + +A G H SA V + GR+ ++G G +GQLG G+ ++ +P
Sbjct: 144 SIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSP 188
>AL133551-1|CAI16031.1| 907|Homo sapiens hect domain and RLD 4
protein.
Length = 907
Score = 77.8 bits (183), Expect = 2e-13
Identities = 60/208 (28%), Positives = 91/208 (43%), Gaps = 23/208 (11%)
Query: 425 DAGGRLLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELW 483
++ + WG +GQLGLG + Q +PQL+ LG V G HS +LT G ++
Sbjct: 3 ESASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIF 62
Query: 484 ACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQ 541
G + FGQLG +P ++ + + + G H ALT +G V+ +GA
Sbjct: 63 GWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYG 122
Query: 542 VXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIV-QISAGWHH-SCIINNMG 599
H+ N R + G IV +I+ G H S + + G
Sbjct: 123 QLGHNSTS-----------HEINPR-------KVFELMGSIVTEIACGRQHTSAFVPSSG 164
Query: 600 SIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
IY++GL +GQLG+G + P VK
Sbjct: 165 RIYSFGLGGNGQLGTGSTSNRKSPFTVK 192
Score = 72.5 bits (170), Expect = 7e-12
Identities = 42/132 (31%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Query: 408 GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVG 467
G P + VAAG HS + G + WG GQLGL + +D++ P L+ +K+ +
Sbjct: 39 GIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYIC 98
Query: 468 CGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV--ALHEPVRALAAGYFHNLA 525
CG H+ LT+ G ++ GA +GQLG P +V + V +A G H A
Sbjct: 99 CGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQHTSA 158
Query: 526 -LTHKGEVYVWG 536
+ G +Y +G
Sbjct: 159 FVPSSGRIYSFG 170
Score = 62.9 bits (146), Expect = 5e-09
Identities = 46/158 (29%), Positives = 70/158 (44%), Gaps = 11/158 (6%)
Query: 352 IDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAP 410
+ VA G H+ +LT +G ++ G N FGQL LR +
Sbjct: 43 MQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKS----LRSQ-----K 93
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA 470
+V + G H+AA+ G + T+G G +GQLG + + P+ V + +G V + CG
Sbjct: 94 IVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGR 153
Query: 471 CH-SVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV 507
H S + G +++ G GQLGTG P V
Sbjct: 154 QHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTV 191
Score = 44.0 bits (99), Expect = 0.003
Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 11/105 (10%)
Query: 350 RVIDVACGRHHTLILT-ENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
+++ + CG HT LT E G+++ G +GQL +V G
Sbjct: 93 KIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPR---------KVFELMG 143
Query: 409 APLVCVAAGHYH-SAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP 452
+ + +A G H SA V + GR+ ++G G +GQLG G+ ++ +P
Sbjct: 144 SIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSP 188
>BC053908-1|AAH53908.1| 522|Homo sapiens RCC2 protein protein.
Length = 522
Score = 77.0 bits (181), Expect = 3e-13
Identities = 64/236 (27%), Positives = 101/236 (42%), Gaps = 23/236 (9%)
Query: 450 WTPQLVTKFLGRKVQSVGCGAC--HSVLLTRGGELWACGASVFGQLGTGQRGKASLP--V 505
W P G +V++V G+C HS+L+T G+LW+ G + GQLG G + P +
Sbjct: 137 WGPHRYGCLAGVRVRTVVSGSCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLI 196
Query: 506 RVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDND 565
HE + + A G H LALT G V+ +G + PS + ++
Sbjct: 197 EGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQ-- 254
Query: 566 RYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLG-SGDRKQIQIPT 624
I +++ G S I++ G++Y++G GQLG + D K I
Sbjct: 255 ---------------PITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQ 299
Query: 625 EVKIRTETQPHTMKSDSEKTTDADENMEFNTKAL-VGCGGDFTVYIDDDGRIYSTG 679
++ E P + EKT D N V CG + T+ +D R++S G
Sbjct: 300 RIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWG 355
Score = 75.4 bits (177), Expect = 1e-12
Identities = 50/218 (22%), Positives = 97/218 (44%), Gaps = 9/218 (4%)
Query: 420 HSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRG 479
HS + G+L +WG GQLG G+ P+L+ + S CG H++ LT
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTET 220
Query: 480 GELWACGASVFGQLGTG-QRGKASLPVRVALH-EPVRALAAGYFHNLALTHKGEVYVWGA 537
G ++A G + GQLG G Q P ++ + +P+ +A G ++ + KG +Y +G
Sbjct: 221 GSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYSFGC 280
Query: 538 SPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTN------VRGRIVQ-ISAGWH 590
+ + + + ++ T V +V+ ++ G +
Sbjct: 281 PEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGAN 340
Query: 591 HSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKI 628
H+ ++++ +++WG G+LG ++K +P VK+
Sbjct: 341 HTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKL 378
Score = 62.5 bits (145), Expect = 7e-09
Identities = 57/217 (26%), Positives = 96/217 (44%), Gaps = 38/217 (17%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
++ ACGR+HTL LTE G +++ G+N GQL + G
Sbjct: 204 IVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQI---------MYNGQ 254
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN------------IDDQWTPQLVTK 457
P+ +A G S +D G L ++G +GQLG + D + P+ V
Sbjct: 255 PITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAI 314
Query: 458 FLGRK------------VQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPV 505
F+ + V+ V CGA H+++L +++ G +G+LG ++ +P
Sbjct: 315 FIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPR 374
Query: 506 RVALHE-PVRA---LAAGYFHNLALTHKGEVYVWGAS 538
V L + P R + AGY + A++ G ++ WGA+
Sbjct: 375 LVKLFDFPGRGASQIYAGYTCSFAVSEVGGLFFWGAT 411
Score = 61.7 bits (143), Expect = 1e-08
Identities = 43/150 (28%), Positives = 62/150 (41%), Gaps = 9/150 (6%)
Query: 351 VIDVACGRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAP 410
V+ +C H LI TE L+S G N GQL +
Sbjct: 153 VVSGSCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEV--------- 203
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA 470
+V A G H+ A+ G + +G GQLGLGN D + G+ + + CGA
Sbjct: 204 IVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGA 263
Query: 471 CHSVLLTRGGELWACGASVFGQLGTGQRGK 500
S+++ G L++ G +GQLG GK
Sbjct: 264 EFSMIMDCKGNLYSFGCPEYGQLGHNSDGK 293
Score = 44.8 bits (101), Expect = 0.002
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 7/128 (5%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVT--KFLGRKVQSVGCGAC 471
VA G H+ +D+ R+ +WG+G +G+LG D+ P+LV F GR + G
Sbjct: 335 VACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYT 394
Query: 472 HSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGE 531
S ++ G L+ GA+ + T KA V+ +R+LA G + +
Sbjct: 395 CSFAVSEVGGLFFWGATNTSREST-MYPKA---VQDLCGWRIRSLACGKSSIIVAADEST 450
Query: 532 VYVWGASP 539
+ WG SP
Sbjct: 451 I-SWGPSP 457
>BC042141-1|AAH42141.1| 522|Homo sapiens regulator of chromosome
condensation 2 protein.
Length = 522
Score = 77.0 bits (181), Expect = 3e-13
Identities = 64/236 (27%), Positives = 101/236 (42%), Gaps = 23/236 (9%)
Query: 450 WTPQLVTKFLGRKVQSVGCGAC--HSVLLTRGGELWACGASVFGQLGTGQRGKASLP--V 505
W P G +V++V G+C HS+L+T G+LW+ G + GQLG G + P +
Sbjct: 137 WGPHRYGCLAGVRVRTVVSGSCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLI 196
Query: 506 RVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDND 565
HE + + A G H LALT G V+ +G + PS + ++
Sbjct: 197 EGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQ-- 254
Query: 566 RYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLG-SGDRKQIQIPT 624
I +++ G S I++ G++Y++G GQLG + D K I
Sbjct: 255 ---------------PITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQ 299
Query: 625 EVKIRTETQPHTMKSDSEKTTDADENMEFNTKAL-VGCGGDFTVYIDDDGRIYSTG 679
++ E P + EKT D N V CG + T+ +D R++S G
Sbjct: 300 RIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWG 355
Score = 75.4 bits (177), Expect = 1e-12
Identities = 50/218 (22%), Positives = 97/218 (44%), Gaps = 9/218 (4%)
Query: 420 HSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRG 479
HS + G+L +WG GQLG G+ P+L+ + S CG H++ LT
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTET 220
Query: 480 GELWACGASVFGQLGTG-QRGKASLPVRVALH-EPVRALAAGYFHNLALTHKGEVYVWGA 537
G ++A G + GQLG G Q P ++ + +P+ +A G ++ + KG +Y +G
Sbjct: 221 GSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYSFGC 280
Query: 538 SPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTN------VRGRIVQ-ISAGWH 590
+ + + + ++ T V +V+ ++ G +
Sbjct: 281 PEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGAN 340
Query: 591 HSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKI 628
H+ ++++ +++WG G+LG ++K +P VK+
Sbjct: 341 HTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKL 378
Score = 62.5 bits (145), Expect = 7e-09
Identities = 57/217 (26%), Positives = 96/217 (44%), Gaps = 38/217 (17%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
++ ACGR+HTL LTE G +++ G+N GQL + G
Sbjct: 204 IVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQI---------MYNGQ 254
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN------------IDDQWTPQLVTK 457
P+ +A G S +D G L ++G +GQLG + D + P+ V
Sbjct: 255 PITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAI 314
Query: 458 FLGRK------------VQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPV 505
F+ + V+ V CGA H+++L +++ G +G+LG ++ +P
Sbjct: 315 FIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPR 374
Query: 506 RVALHE-PVRA---LAAGYFHNLALTHKGEVYVWGAS 538
V L + P R + AGY + A++ G ++ WGA+
Sbjct: 375 LVKLFDFPGRGASQIYAGYTCSFAVSEVGGLFFWGAT 411
Score = 61.7 bits (143), Expect = 1e-08
Identities = 43/150 (28%), Positives = 62/150 (41%), Gaps = 9/150 (6%)
Query: 351 VIDVACGRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAP 410
V+ +C H LI TE L+S G N GQL +
Sbjct: 153 VVSGSCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEV--------- 203
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA 470
+V A G H+ A+ G + +G GQLGLGN D + G+ + + CGA
Sbjct: 204 IVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGA 263
Query: 471 CHSVLLTRGGELWACGASVFGQLGTGQRGK 500
S+++ G L++ G +GQLG GK
Sbjct: 264 EFSMIMDCKGNLYSFGCPEYGQLGHNSDGK 293
Score = 44.8 bits (101), Expect = 0.002
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 7/128 (5%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVT--KFLGRKVQSVGCGAC 471
VA G H+ +D+ R+ +WG+G +G+LG D+ P+LV F GR + G
Sbjct: 335 VACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYT 394
Query: 472 HSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGE 531
S ++ G L+ GA+ + T KA V+ +R+LA G + +
Sbjct: 395 CSFAVSEVGGLFFWGATNTSREST-MYPKA---VQDLCGWRIRSLACGKSSIIVAADEST 450
Query: 532 VYVWGASP 539
+ WG SP
Sbjct: 451 I-SWGPSP 457
>AJ421269-1|CAD13148.1| 522|Homo sapiens RCC1-like protein protein.
Length = 522
Score = 77.0 bits (181), Expect = 3e-13
Identities = 64/236 (27%), Positives = 101/236 (42%), Gaps = 23/236 (9%)
Query: 450 WTPQLVTKFLGRKVQSVGCGAC--HSVLLTRGGELWACGASVFGQLGTGQRGKASLP--V 505
W P G +V++V G+C HS+L+T G+LW+ G + GQLG G + P +
Sbjct: 137 WGPHRYGCLAGVRVRTVVSGSCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLI 196
Query: 506 RVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDND 565
HE + + A G H LALT G V+ +G + PS + ++
Sbjct: 197 EGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQ-- 254
Query: 566 RYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLG-SGDRKQIQIPT 624
I +++ G S I++ G++Y++G GQLG + D K I
Sbjct: 255 ---------------PITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQ 299
Query: 625 EVKIRTETQPHTMKSDSEKTTDADENMEFNTKAL-VGCGGDFTVYIDDDGRIYSTG 679
++ E P + EKT D N V CG + T+ +D R++S G
Sbjct: 300 RIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWG 355
Score = 75.4 bits (177), Expect = 1e-12
Identities = 50/218 (22%), Positives = 97/218 (44%), Gaps = 9/218 (4%)
Query: 420 HSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRG 479
HS + G+L +WG GQLG G+ P+L+ + S CG H++ LT
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTET 220
Query: 480 GELWACGASVFGQLGTG-QRGKASLPVRVALH-EPVRALAAGYFHNLALTHKGEVYVWGA 537
G ++A G + GQLG G Q P ++ + +P+ +A G ++ + KG +Y +G
Sbjct: 221 GSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYSFGC 280
Query: 538 SPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTN------VRGRIVQ-ISAGWH 590
+ + + + ++ T V +V+ ++ G +
Sbjct: 281 PEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGAN 340
Query: 591 HSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKI 628
H+ ++++ +++WG G+LG ++K +P VK+
Sbjct: 341 HTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKL 378
Score = 62.5 bits (145), Expect = 7e-09
Identities = 57/217 (26%), Positives = 96/217 (44%), Gaps = 38/217 (17%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
++ ACGR+HTL LTE G +++ G+N GQL + G
Sbjct: 204 IVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQI---------MYNGQ 254
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN------------IDDQWTPQLVTK 457
P+ +A G S +D G L ++G +GQLG + D + P+ V
Sbjct: 255 PITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAI 314
Query: 458 FLGRK------------VQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPV 505
F+ + V+ V CGA H+++L +++ G +G+LG ++ +P
Sbjct: 315 FIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPR 374
Query: 506 RVALHE-PVRA---LAAGYFHNLALTHKGEVYVWGAS 538
V L + P R + AGY + A++ G ++ WGA+
Sbjct: 375 LVKLFDFPGRGASQIYAGYTCSFAVSEVGGLFFWGAT 411
Score = 61.7 bits (143), Expect = 1e-08
Identities = 43/150 (28%), Positives = 62/150 (41%), Gaps = 9/150 (6%)
Query: 351 VIDVACGRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAP 410
V+ +C H LI TE L+S G N GQL +
Sbjct: 153 VVSGSCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEV--------- 203
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA 470
+V A G H+ A+ G + +G GQLGLGN D + G+ + + CGA
Sbjct: 204 IVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGA 263
Query: 471 CHSVLLTRGGELWACGASVFGQLGTGQRGK 500
S+++ G L++ G +GQLG GK
Sbjct: 264 EFSMIMDCKGNLYSFGCPEYGQLGHNSDGK 293
Score = 44.8 bits (101), Expect = 0.002
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 7/128 (5%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVT--KFLGRKVQSVGCGAC 471
VA G H+ +D+ R+ +WG+G +G+LG D+ P+LV F GR + G
Sbjct: 335 VACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYT 394
Query: 472 HSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGE 531
S ++ G L+ GA+ + T KA V+ +R+LA G + +
Sbjct: 395 CSFAVSEVGGLFFWGATNTSREST-MYPKA---VQDLCGWRIRSLACGKSSIIVAADEST 450
Query: 532 VYVWGASP 539
+ WG SP
Sbjct: 451 I-SWGPSP 457
>AB040903-1|BAA95994.1| 564|Homo sapiens KIAA1470 protein protein.
Length = 564
Score = 77.0 bits (181), Expect = 3e-13
Identities = 64/236 (27%), Positives = 101/236 (42%), Gaps = 23/236 (9%)
Query: 450 WTPQLVTKFLGRKVQSVGCGAC--HSVLLTRGGELWACGASVFGQLGTGQRGKASLP--V 505
W P G +V++V G+C HS+L+T G+LW+ G + GQLG G + P +
Sbjct: 179 WGPHRYGCLAGVRVRTVVSGSCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLI 238
Query: 506 RVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDND 565
HE + + A G H LALT G V+ +G + PS + ++
Sbjct: 239 EGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQ-- 296
Query: 566 RYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLG-SGDRKQIQIPT 624
I +++ G S I++ G++Y++G GQLG + D K I
Sbjct: 297 ---------------PITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQ 341
Query: 625 EVKIRTETQPHTMKSDSEKTTDADENMEFNTKAL-VGCGGDFTVYIDDDGRIYSTG 679
++ E P + EKT D N V CG + T+ +D R++S G
Sbjct: 342 RIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWG 397
Score = 75.4 bits (177), Expect = 1e-12
Identities = 50/218 (22%), Positives = 97/218 (44%), Gaps = 9/218 (4%)
Query: 420 HSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRG 479
HS + G+L +WG GQLG G+ P+L+ + S CG H++ LT
Sbjct: 203 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTET 262
Query: 480 GELWACGASVFGQLGTG-QRGKASLPVRVALH-EPVRALAAGYFHNLALTHKGEVYVWGA 537
G ++A G + GQLG G Q P ++ + +P+ +A G ++ + KG +Y +G
Sbjct: 263 GSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYSFGC 322
Query: 538 SPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTN------VRGRIVQ-ISAGWH 590
+ + + + ++ T V +V+ ++ G +
Sbjct: 323 PEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGAN 382
Query: 591 HSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKI 628
H+ ++++ +++WG G+LG ++K +P VK+
Sbjct: 383 HTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKL 420
Score = 62.5 bits (145), Expect = 7e-09
Identities = 57/217 (26%), Positives = 96/217 (44%), Gaps = 38/217 (17%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
++ ACGR+HTL LTE G +++ G+N GQL + G
Sbjct: 246 IVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQI---------MYNGQ 296
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN------------IDDQWTPQLVTK 457
P+ +A G S +D G L ++G +GQLG + D + P+ V
Sbjct: 297 PITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAI 356
Query: 458 FLGRK------------VQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPV 505
F+ + V+ V CGA H+++L +++ G +G+LG ++ +P
Sbjct: 357 FIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPR 416
Query: 506 RVALHE-PVRA---LAAGYFHNLALTHKGEVYVWGAS 538
V L + P R + AGY + A++ G ++ WGA+
Sbjct: 417 LVKLFDFPGRGASQIYAGYTCSFAVSEVGGLFFWGAT 453
Score = 61.7 bits (143), Expect = 1e-08
Identities = 43/150 (28%), Positives = 62/150 (41%), Gaps = 9/150 (6%)
Query: 351 VIDVACGRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAP 410
V+ +C H LI TE L+S G N GQL +
Sbjct: 195 VVSGSCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEV--------- 245
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA 470
+V A G H+ A+ G + +G GQLGLGN D + G+ + + CGA
Sbjct: 246 IVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGA 305
Query: 471 CHSVLLTRGGELWACGASVFGQLGTGQRGK 500
S+++ G L++ G +GQLG GK
Sbjct: 306 EFSMIMDCKGNLYSFGCPEYGQLGHNSDGK 335
Score = 44.8 bits (101), Expect = 0.002
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 7/128 (5%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVT--KFLGRKVQSVGCGAC 471
VA G H+ +D+ R+ +WG+G +G+LG D+ P+LV F GR + G
Sbjct: 377 VACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYT 436
Query: 472 HSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGE 531
S ++ G L+ GA+ + T KA V+ +R+LA G + +
Sbjct: 437 CSFAVSEVGGLFFWGATNTSREST-MYPKA---VQDLCGWRIRSLACGKSSIIVAADEST 492
Query: 532 VYVWGASP 539
+ WG SP
Sbjct: 493 I-SWGPSP 499
>BC019008-1|AAH19008.1| 464|Homo sapiens Williams-Beuren syndrome
chromosome region 16 protein.
Length = 464
Score = 76.2 bits (179), Expect = 5e-13
Identities = 83/301 (27%), Positives = 124/301 (41%), Gaps = 29/301 (9%)
Query: 340 STPVNTELIGRVIDVACGRHHTLILTEN-GLYSAGDNTFGQLXXXXXXXXXXXXXXXXXX 398
S P++ RV+ V+CGR H+L+LT+ G++S G+N++GQ
Sbjct: 165 SLPLDRPQETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHR--- 221
Query: 399 XVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTK 457
V R++ G +V VA G HS + G + + GWG GQ GLG+ + +P +L
Sbjct: 222 -VHRMQDFDGQ-VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGD 279
Query: 458 FLGRKVQSVGC-GACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALH----EP 512
G V V G C + GG L+ G S + QL + + V LH
Sbjct: 280 LAGVNVIQVATYGDCCLAVSADGG-LFGWGNSEYLQLAS-VTDSTQVNVPRCLHFSGVGK 337
Query: 513 VRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSC 572
VR A G L +G V+VWG E + P + + P+
Sbjct: 338 VRQAACGGTGCAVLNGEGHVFVWGYG----ILGKGPNLVESAVPEM---------IPPTL 384
Query: 573 VDTT--NVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRT 630
T N ++ +I G H + N G ++ WG N G LG G + P V +
Sbjct: 385 FGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRVTMPG 444
Query: 631 E 631
E
Sbjct: 445 E 445
Score = 51.2 bits (117), Expect = 2e-05
Identities = 57/216 (26%), Positives = 89/216 (41%), Gaps = 18/216 (8%)
Query: 320 TCGLAHWAVVSDGNARVMMASTPVNTELIG-RVIDVAC-GRHHTLILTENGLYSAGDNTF 377
+CG G+ + + T + +L G VI VA G + + GL+ G++ +
Sbjct: 253 SCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDCCLAVSADGGLFGWGNSEY 312
Query: 378 GQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGV 437
QL V +VR A A G A ++ G + WG+G+
Sbjct: 313 LQLASVTDSTQVNVPRCLHFSGVGKVRQA--------ACGGTGCAVLNGEGHVFVWGYGI 364
Query: 438 HGQ---LGLGNIDDQWTPQL--VTKFLGR-KVQSVGCGACHSVLLTRGGELWACGASVFG 491
G+ L + + P L +T+F +V + CG H LT GEL+ G ++ G
Sbjct: 365 LGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGKNIRG 424
Query: 492 QLGTGQRGKASLPVRVAL-HEPVRALAAGYFHNLAL 526
LG G+ P RV + EPV +A G H + L
Sbjct: 425 CLGIGRLEDQYFPWRVTMPGEPV-DVACGVDHMVTL 459
Score = 46.0 bits (104), Expect = 7e-04
Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHS 473
+ G H AA+ G L WG + G LG+G ++DQ+ P VT G V V CG H
Sbjct: 399 IRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRVT-MPGEPV-DVACGVDHM 456
Query: 474 VLLTR 478
V L +
Sbjct: 457 VTLAK 461
>BC007823-1|AAH07823.1| 464|Homo sapiens Williams-Beuren syndrome
chromosome region 16 protein.
Length = 464
Score = 76.2 bits (179), Expect = 5e-13
Identities = 83/301 (27%), Positives = 124/301 (41%), Gaps = 29/301 (9%)
Query: 340 STPVNTELIGRVIDVACGRHHTLILTEN-GLYSAGDNTFGQLXXXXXXXXXXXXXXXXXX 398
S P++ RV+ V+CGR H+L+LT+ G++S G+N++GQ
Sbjct: 165 SLPLDRPQETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHR--- 221
Query: 399 XVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTK 457
V R++ G +V VA G HS + G + + GWG GQ GLG+ + +P +L
Sbjct: 222 -VHRMQDFDGQ-VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGD 279
Query: 458 FLGRKVQSVGC-GACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALH----EP 512
G V V G C + GG L+ G S + QL + + V LH
Sbjct: 280 LAGVNVIQVATYGDCCLAVSADGG-LFGWGNSEYLQLAS-VTDSTQVNVPRCLHFSGVGK 337
Query: 513 VRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSC 572
VR A G L +G V+VWG E + P + + P+
Sbjct: 338 VRQAACGGTGCAVLNGEGHVFVWGYG----ILGKGPNLVESAVPEM---------IPPTL 384
Query: 573 VDTT--NVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRT 630
T N ++ +I G H + N G ++ WG N G LG G + P V +
Sbjct: 385 FGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRVTMPG 444
Query: 631 E 631
E
Sbjct: 445 E 445
Score = 51.2 bits (117), Expect = 2e-05
Identities = 57/216 (26%), Positives = 89/216 (41%), Gaps = 18/216 (8%)
Query: 320 TCGLAHWAVVSDGNARVMMASTPVNTELIG-RVIDVAC-GRHHTLILTENGLYSAGDNTF 377
+CG G+ + + T + +L G VI VA G + + GL+ G++ +
Sbjct: 253 SCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDCCLAVSADGGLFGWGNSEY 312
Query: 378 GQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGV 437
QL V +VR A A G A ++ G + WG+G+
Sbjct: 313 LQLASVTDSTQVNVPRCLHFSGVGKVRQA--------ACGGTGCAVLNGEGHVFVWGYGI 364
Query: 438 HGQ---LGLGNIDDQWTPQL--VTKFLGR-KVQSVGCGACHSVLLTRGGELWACGASVFG 491
G+ L + + P L +T+F +V + CG H LT GEL+ G ++ G
Sbjct: 365 LGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGKNIRG 424
Query: 492 QLGTGQRGKASLPVRVAL-HEPVRALAAGYFHNLAL 526
LG G+ P RV + EPV +A G H + L
Sbjct: 425 CLGIGRLEDQYFPWRVTMPGEPV-DVACGVDHMVTL 459
Score = 46.0 bits (104), Expect = 7e-04
Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHS 473
+ G H AA+ G L WG + G LG+G ++DQ+ P VT G V V CG H
Sbjct: 399 IRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRVT-MPGEPV-DVACGVDHM 456
Query: 474 VLLTR 478
V L +
Sbjct: 457 VTLAK 461
>AF410455-1|AAM62304.1| 464|Homo sapiens RCC1-like G exchanging
factor-like protein protein.
Length = 464
Score = 76.2 bits (179), Expect = 5e-13
Identities = 83/301 (27%), Positives = 124/301 (41%), Gaps = 29/301 (9%)
Query: 340 STPVNTELIGRVIDVACGRHHTLILTEN-GLYSAGDNTFGQLXXXXXXXXXXXXXXXXXX 398
S P++ RV+ V+CGR H+L+LT+ G++S G+N++GQ
Sbjct: 165 SLPLDRPQETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHR--- 221
Query: 399 XVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTK 457
V R++ G +V VA G HS + G + + GWG GQ GLG+ + +P +L
Sbjct: 222 -VHRMQDFDGQ-VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGD 279
Query: 458 FLGRKVQSVGC-GACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALH----EP 512
G V V G C + GG L+ G S + QL + + V LH
Sbjct: 280 LAGVNVIQVATYGDCCLAVSADGG-LFGWGNSEYLQLAS-VTDSTQVNVPRCLHFSGVGK 337
Query: 513 VRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSC 572
VR A G L +G V+VWG E + P + + P+
Sbjct: 338 VRQAACGGTGCAVLNGEGHVFVWGYG----ILGKGPNLVESAVPEM---------IPPTL 384
Query: 573 VDTT--NVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRT 630
T N ++ +I G H + N G ++ WG N G LG G + P V +
Sbjct: 385 FGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRVTMPG 444
Query: 631 E 631
E
Sbjct: 445 E 445
Score = 51.2 bits (117), Expect = 2e-05
Identities = 57/216 (26%), Positives = 89/216 (41%), Gaps = 18/216 (8%)
Query: 320 TCGLAHWAVVSDGNARVMMASTPVNTELIG-RVIDVAC-GRHHTLILTENGLYSAGDNTF 377
+CG G+ + + T + +L G VI VA G + + GL+ G++ +
Sbjct: 253 SCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDCCLAVSADGGLFGWGNSEY 312
Query: 378 GQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGV 437
QL V +VR A A G A ++ G + WG+G+
Sbjct: 313 LQLASVTDSTQVNVPRCLHFSGVGKVRQA--------ACGGTGCAVLNGEGHVFVWGYGI 364
Query: 438 HGQ---LGLGNIDDQWTPQL--VTKFLGR-KVQSVGCGACHSVLLTRGGELWACGASVFG 491
G+ L + + P L +T+F +V + CG H LT GEL+ G ++ G
Sbjct: 365 LGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGKNIRG 424
Query: 492 QLGTGQRGKASLPVRVAL-HEPVRALAAGYFHNLAL 526
LG G+ P RV + EPV +A G H + L
Sbjct: 425 CLGIGRLEDQYFPWRVTMPGEPV-DVACGVDHMVTL 459
Score = 46.0 bits (104), Expect = 7e-04
Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHS 473
+ G H AA+ G L WG + G LG+G ++DQ+ P VT G V V CG H
Sbjct: 399 IRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRVT-MPGEPV-DVACGVDHM 456
Query: 474 VLLTR 478
V L +
Sbjct: 457 VTLAK 461
>AL359612-1|CAB94882.1| 333|Homo sapiens hypothetical protein
protein.
Length = 333
Score = 75.4 bits (177), Expect = 1e-12
Identities = 50/218 (22%), Positives = 97/218 (44%), Gaps = 9/218 (4%)
Query: 420 HSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRG 479
HS + G+L +WG GQLG G+ P+L+ + S CG H++ LT
Sbjct: 17 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTET 76
Query: 480 GELWACGASVFGQLGTG-QRGKASLPVRVALH-EPVRALAAGYFHNLALTHKGEVYVWGA 537
G ++A G + GQLG G Q P ++ + +P+ +A G ++ + KG +Y +G
Sbjct: 77 GSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYSFGC 136
Query: 538 SPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTN------VRGRIVQ-ISAGWH 590
+ + + + ++ T V +V+ ++ G +
Sbjct: 137 PEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGAN 196
Query: 591 HSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKI 628
H+ ++++ +++WG G+LG ++K +P VK+
Sbjct: 197 HTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKL 234
Score = 72.9 bits (171), Expect = 5e-12
Identities = 61/224 (27%), Positives = 98/224 (43%), Gaps = 23/224 (10%)
Query: 462 KVQSVGCGAC--HSVLLTRGGELWACGASVFGQLGTGQRGKASLP--VRVALHEPVRALA 517
+V++V G+C HS+L+T G+LW+ G + GQLG G + P + HE + + A
Sbjct: 5 RVRTVVSGSCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAA 64
Query: 518 AGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTN 577
G H LALT G V+ +G + PS + ++
Sbjct: 65 CGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQ-------------- 110
Query: 578 VRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLG-SGDRKQIQIPTEVKIRTETQPHT 636
I +++ G S I++ G++Y++G GQLG + D K I ++ E P
Sbjct: 111 ---PITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRR 167
Query: 637 MKSDSEKTTDADENMEFNTKAL-VGCGGDFTVYIDDDGRIYSTG 679
+ EKT D N V CG + T+ +D R++S G
Sbjct: 168 VAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWG 211
Score = 62.5 bits (145), Expect = 7e-09
Identities = 57/217 (26%), Positives = 96/217 (44%), Gaps = 38/217 (17%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
++ ACGR+HTL LTE G +++ G+N GQL + G
Sbjct: 60 IVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQI---------MYNGQ 110
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN------------IDDQWTPQLVTK 457
P+ +A G S +D G L ++G +GQLG + D + P+ V
Sbjct: 111 PITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAI 170
Query: 458 FLGRK------------VQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPV 505
F+ + V+ V CGA H+++L +++ G +G+LG ++ +P
Sbjct: 171 FIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPR 230
Query: 506 RVALHE-PVRA---LAAGYFHNLALTHKGEVYVWGAS 538
V L + P R + AGY + A++ G ++ WGA+
Sbjct: 231 LVKLFDFPGRGASQIYAGYTCSFAVSEVGGLFFWGAT 267
Score = 61.7 bits (143), Expect = 1e-08
Identities = 43/150 (28%), Positives = 62/150 (41%), Gaps = 9/150 (6%)
Query: 351 VIDVACGRHHTLILTENGLYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAP 410
V+ +C H LI TE L+S G N GQL +
Sbjct: 9 VVSGSCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEV--------- 59
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA 470
+V A G H+ A+ G + +G GQLGLGN D + G+ + + CGA
Sbjct: 60 IVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGA 119
Query: 471 CHSVLLTRGGELWACGASVFGQLGTGQRGK 500
S+++ G L++ G +GQLG GK
Sbjct: 120 EFSMIMDCKGNLYSFGCPEYGQLGHNSDGK 149
Score = 44.8 bits (101), Expect = 0.002
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 7/128 (5%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVT--KFLGRKVQSVGCGAC 471
VA G H+ +D+ R+ +WG+G +G+LG D+ P+LV F GR + G
Sbjct: 191 VACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYT 250
Query: 472 HSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGE 531
S ++ G L+ GA+ + T KA V+ +R+LA G + +
Sbjct: 251 CSFAVSEVGGLFFWGATNTSREST-MYPKA---VQDLCGWRIRSLACGKSSIIVAADEST 306
Query: 532 VYVWGASP 539
+ WG SP
Sbjct: 307 I-SWGPSP 313
Score = 42.7 bits (96), Expect = 0.006
Identities = 19/47 (40%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
Query: 579 RGRIVQISAGW--HHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIP 623
RGR+ + +G HS +I G +++WG N GQLG GD K+++ P
Sbjct: 3 RGRVRTVVSGSCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAP 49
>BC032712-1|AAH32712.1| 454|Homo sapiens WBSCR16 protein protein.
Length = 454
Score = 74.9 bits (176), Expect = 1e-12
Identities = 80/285 (28%), Positives = 119/285 (41%), Gaps = 29/285 (10%)
Query: 340 STPVNTELIGRVIDVACGRHHTLILTEN-GLYSAGDNTFGQLXXXXXXXXXXXXXXXXXX 398
S P++ RV+ V+CGR H+L+LT+ G++S G+N++GQ
Sbjct: 165 SLPLDRPQETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHR--- 221
Query: 399 XVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTK 457
V R++ G +V VA G HS + G + + GWG GQ GLG+ + +P +L
Sbjct: 222 -VHRMQDFDGQ-VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGD 279
Query: 458 FLGRKVQSVGC-GACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALH----EP 512
G V V G C + GG L+ G S + QL + + V LH
Sbjct: 280 LAGVNVIQVATYGDCCLAVSADGG-LFGWGNSEYLQLAS-VTDSTQVNVPRCLHFSGVGK 337
Query: 513 VRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSC 572
VR A G L +G V+VWG E + P + + P+
Sbjct: 338 VRQAACGGTGCAVLNGEGHVFVWGYG----ILGKGPNLVESAVPEM---------IPPTL 384
Query: 573 VDTT--NVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSG 615
T N ++ +I G H + N G ++ WG N G LG G
Sbjct: 385 FGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGKNIRGCLGIG 429
Score = 45.6 bits (103), Expect = 9e-04
Identities = 49/195 (25%), Positives = 78/195 (40%), Gaps = 16/195 (8%)
Query: 320 TCGLAHWAVVSDGNARVMMASTPVNTELIG-RVIDVAC-GRHHTLILTENGLYSAGDNTF 377
+CG G+ + + T + +L G VI VA G + + GL+ G++ +
Sbjct: 253 SCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDCCLAVSADGGLFGWGNSEY 312
Query: 378 GQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGV 437
QL V +VR A A G A ++ G + WG+G+
Sbjct: 313 LQLASVTDSTQVNVPRCLHFSGVGKVRQA--------ACGGTGCAVLNGEGHVFVWGYGI 364
Query: 438 HGQ---LGLGNIDDQWTPQL--VTKFLGR-KVQSVGCGACHSVLLTRGGELWACGASVFG 491
G+ L + + P L +T+F +V + CG H LT GEL+ G ++ G
Sbjct: 365 LGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGKNIRG 424
Query: 492 QLGTGQRGKASLPVR 506
LG G+ P R
Sbjct: 425 CLGIGRLEDQYFPWR 439
Score = 39.1 bits (87), Expect = 0.077
Identities = 16/47 (34%), Positives = 26/47 (55%)
Query: 580 GRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEV 626
G++VQ++ G HS + + G +Y+ G DGQ G G PT++
Sbjct: 230 GQVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKL 276
>X12654-1|CAA31182.1| 421|Homo sapiens protein ( Human mRNA for
cell cycle gene RCC1. ).
Length = 421
Score = 70.1 bits (164), Expect = 4e-11
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 21/189 (11%)
Query: 428 GRLLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACG 486
G +LT G G GQLGLG N+ ++ P LV+ + V G H+V L++ G++++ G
Sbjct: 35 GLVLTLGQGDVGQLGLGENVMERKKPALVS--IPEDVVQAEAGGMHTVCLSKSGQVYSFG 92
Query: 487 ASVFGQLG--TGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXX 544
+ G LG T G +P +V L E V ++AG H ALT G V++WG+
Sbjct: 93 CNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGS------- 145
Query: 545 XXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTW 604
++ + + + + P V + +V++++G H ++ G +YT
Sbjct: 146 ------FRDNNGVIGLLEPMKKSMVPVQV---QLDVPVVKVASGNDHLVMLTADGDLYTL 196
Query: 605 GLNFDGQLG 613
G GQLG
Sbjct: 197 GCGEQGQLG 205
Score = 61.3 bits (142), Expect = 2e-08
Identities = 55/206 (26%), Positives = 89/206 (43%), Gaps = 11/206 (5%)
Query: 342 PVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXV 400
PV +L V+ VA G H ++LT +G LY+ G GQL +
Sbjct: 165 PVQVQLDVPVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL 224
Query: 401 ------LRVRLAGGAPLVCVA-AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQ 453
L+ R + G A G Y + A+ G + +G + QLG + + PQ
Sbjct: 225 VPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQ 284
Query: 454 LVTKFLGRKVQSVGC--GACHSVLLTRGGELWACGASVFGQLGTGQRGKA-SLPVRVALH 510
+T F VG G H+V + G+ ++ G + +G+LG G+ + S+P ++
Sbjct: 285 NLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRL 344
Query: 511 EPVRALAAGYFHNLALTHKGEVYVWG 536
V ++A G A+T G V+ WG
Sbjct: 345 PAVSSVACGASVGYAVTKDGRVFAWG 370
Score = 57.2 bits (132), Expect = 3e-07
Identities = 71/252 (28%), Positives = 105/252 (41%), Gaps = 28/252 (11%)
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDD--QWTPQLVTKFLGRKVQSVGC 468
+V AG H+ + G++ ++G G LG + + P V L KV V
Sbjct: 69 VVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE--LQEKVVQVSA 126
Query: 469 GACHSVLLTRGGE--LWACGASVFGQLGTGQRGKASL-PVRVALHEPVRALAAGYFHNLA 525
G H+ LT G LW G +G + K S+ PV+V L PV +A+G H +
Sbjct: 127 GDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVM 186
Query: 526 LTHKGEVYVWGASPQ-QVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCV--DTTNVRG-- 580
LT G++Y G Q Q+ L +R L P CV + RG
Sbjct: 187 LTADGDLYTLGCGEQGQLGRVPELFANRGGRQGL------ERLLVPKCVMLKSRGSRGHV 240
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIP---TEVKIRTET----- 632
R G + + I++ G +Y +GL+ QLG+ + IP T K T++
Sbjct: 241 RFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFS 300
Query: 633 --QPHTMKSDSE 642
Q HT+ DSE
Sbjct: 301 GGQHHTVCMDSE 312
Score = 54.8 bits (126), Expect = 1e-06
Identities = 31/94 (32%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Query: 415 AAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN-IDDQWTPQLVTKFLGRKVQSVGCGACHS 473
+ G +H+ +D+ G+ + G +G+LGLG +++ P L+++ V SV CGA
Sbjct: 300 SGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVG 357
Query: 474 VLLTRGGELWACGASVFGQLGTGQRGKASLPVRV 507
+T+ G ++A G QLGTGQ A PV +
Sbjct: 358 YAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEM 391
Score = 54.0 bits (124), Expect = 3e-06
Identities = 42/128 (32%), Positives = 59/128 (46%), Gaps = 13/128 (10%)
Query: 357 GRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVA 415
G+HHT+ + G YS G +G+L L RL + + C A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPT-------LISRLPAVSSVACGA 354
Query: 416 AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTKFL-GRKVQSVGCGACHS 473
+ Y AV GR+ WG G + QLG G +D W+P +++ K L R V SV G H+
Sbjct: 355 SVGY---AVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHT 411
Query: 474 VLLTRGGE 481
VLL + E
Sbjct: 412 VLLVKDKE 419
>X06130-1|CAA29496.1| 421|Homo sapiens protein ( Human mRNA for
cell cycle gene RCC1. ).
Length = 421
Score = 70.1 bits (164), Expect = 4e-11
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 21/189 (11%)
Query: 428 GRLLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACG 486
G +LT G G GQLGLG N+ ++ P LV+ + V G H+V L++ G++++ G
Sbjct: 35 GLVLTLGQGDVGQLGLGENVMERKKPALVS--IPEDVVQAEAGGMHTVCLSKSGQVYSFG 92
Query: 487 ASVFGQLG--TGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXX 544
+ G LG T G +P +V L E V ++AG H ALT G V++WG+
Sbjct: 93 CNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGS------- 145
Query: 545 XXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTW 604
++ + + + + P V + +V++++G H ++ G +YT
Sbjct: 146 ------FRDNNGVIGLLEPMKKSMVPVQV---QLDVPVVKVASGNDHLVMLTADGDLYTL 196
Query: 605 GLNFDGQLG 613
G GQLG
Sbjct: 197 GCGEQGQLG 205
Score = 61.3 bits (142), Expect = 2e-08
Identities = 55/206 (26%), Positives = 89/206 (43%), Gaps = 11/206 (5%)
Query: 342 PVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXV 400
PV +L V+ VA G H ++LT +G LY+ G GQL +
Sbjct: 165 PVQVQLDVPVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL 224
Query: 401 ------LRVRLAGGAPLVCVA-AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQ 453
L+ R + G A G Y + A+ G + +G + QLG + + PQ
Sbjct: 225 VPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQ 284
Query: 454 LVTKFLGRKVQSVGC--GACHSVLLTRGGELWACGASVFGQLGTGQRGKA-SLPVRVALH 510
+T F VG G H+V + G+ ++ G + +G+LG G+ + S+P ++
Sbjct: 285 NLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRL 344
Query: 511 EPVRALAAGYFHNLALTHKGEVYVWG 536
V ++A G A+T G V+ WG
Sbjct: 345 PAVSSVACGASVGYAVTKDGRVFAWG 370
Score = 57.2 bits (132), Expect = 3e-07
Identities = 71/252 (28%), Positives = 105/252 (41%), Gaps = 28/252 (11%)
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDD--QWTPQLVTKFLGRKVQSVGC 468
+V AG H+ + G++ ++G G LG + + P V L KV V
Sbjct: 69 VVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE--LQEKVVQVSA 126
Query: 469 GACHSVLLTRGGE--LWACGASVFGQLGTGQRGKASL-PVRVALHEPVRALAAGYFHNLA 525
G H+ LT G LW G +G + K S+ PV+V L PV +A+G H +
Sbjct: 127 GDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVM 186
Query: 526 LTHKGEVYVWGASPQ-QVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCV--DTTNVRG-- 580
LT G++Y G Q Q+ L +R L P CV + RG
Sbjct: 187 LTADGDLYTLGCGEQGQLGRVPELFANRGGRQGL------ERLLVPKCVMLKSRGSRGHV 240
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIP---TEVKIRTET----- 632
R G + + I++ G +Y +GL+ QLG+ + IP T K T++
Sbjct: 241 RFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFS 300
Query: 633 --QPHTMKSDSE 642
Q HT+ DSE
Sbjct: 301 GGQHHTVCMDSE 312
Score = 54.8 bits (126), Expect = 1e-06
Identities = 31/94 (32%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Query: 415 AAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN-IDDQWTPQLVTKFLGRKVQSVGCGACHS 473
+ G +H+ +D+ G+ + G +G+LGLG +++ P L+++ V SV CGA
Sbjct: 300 SGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVG 357
Query: 474 VLLTRGGELWACGASVFGQLGTGQRGKASLPVRV 507
+T+ G ++A G QLGTGQ A PV +
Sbjct: 358 YAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEM 391
Score = 54.0 bits (124), Expect = 3e-06
Identities = 42/128 (32%), Positives = 59/128 (46%), Gaps = 13/128 (10%)
Query: 357 GRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVA 415
G+HHT+ + G YS G +G+L L RL + + C A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPT-------LISRLPAVSSVACGA 354
Query: 416 AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTKFL-GRKVQSVGCGACHS 473
+ Y AV GR+ WG G + QLG G +D W+P +++ K L R V SV G H+
Sbjct: 355 SVGY---AVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHT 411
Query: 474 VLLTRGGE 481
VLL + E
Sbjct: 412 VLLVKDKE 419
>D00591-1|BAA00469.1| 421|Homo sapiens RCC1 protein.
Length = 421
Score = 70.1 bits (164), Expect = 4e-11
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 21/189 (11%)
Query: 428 GRLLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACG 486
G +LT G G GQLGLG N+ ++ P LV+ + V G H+V L++ G++++ G
Sbjct: 35 GLVLTLGQGDVGQLGLGENVMERKKPALVS--IPEDVVQAEAGGMHTVCLSKSGQVYSFG 92
Query: 487 ASVFGQLG--TGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXX 544
+ G LG T G +P +V L E V ++AG H ALT G V++WG+
Sbjct: 93 CNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGS------- 145
Query: 545 XXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTW 604
++ + + + + P V + +V++++G H ++ G +YT
Sbjct: 146 ------FRDNNGVIGLLEPMKKSMVPVQV---QLDVPVVKVASGNDHLVMLTADGDLYTL 196
Query: 605 GLNFDGQLG 613
G GQLG
Sbjct: 197 GCGEQGQLG 205
Score = 61.3 bits (142), Expect = 2e-08
Identities = 55/206 (26%), Positives = 89/206 (43%), Gaps = 11/206 (5%)
Query: 342 PVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXV 400
PV +L V+ VA G H ++LT +G LY+ G GQL +
Sbjct: 165 PVQVQLDVPVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL 224
Query: 401 ------LRVRLAGGAPLVCVA-AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQ 453
L+ R + G A G Y + A+ G + +G + QLG + + PQ
Sbjct: 225 VPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQ 284
Query: 454 LVTKFLGRKVQSVGC--GACHSVLLTRGGELWACGASVFGQLGTGQRGKA-SLPVRVALH 510
+T F VG G H+V + G+ ++ G + +G+LG G+ + S+P ++
Sbjct: 285 NLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRL 344
Query: 511 EPVRALAAGYFHNLALTHKGEVYVWG 536
V ++A G A+T G V+ WG
Sbjct: 345 PAVSSVACGASVGYAVTKDGRVFAWG 370
Score = 57.2 bits (132), Expect = 3e-07
Identities = 71/252 (28%), Positives = 105/252 (41%), Gaps = 28/252 (11%)
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDD--QWTPQLVTKFLGRKVQSVGC 468
+V AG H+ + G++ ++G G LG + + P V L KV V
Sbjct: 69 VVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE--LQEKVVQVSA 126
Query: 469 GACHSVLLTRGGE--LWACGASVFGQLGTGQRGKASL-PVRVALHEPVRALAAGYFHNLA 525
G H+ LT G LW G +G + K S+ PV+V L PV +A+G H +
Sbjct: 127 GDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVM 186
Query: 526 LTHKGEVYVWGASPQ-QVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCV--DTTNVRG-- 580
LT G++Y G Q Q+ L +R L P CV + RG
Sbjct: 187 LTADGDLYTLGCGEQGQLGRVPELFANRGGRQGL------ERLLVPKCVMLKSRGSRGHV 240
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIP---TEVKIRTET----- 632
R G + + I++ G +Y +GL+ QLG+ + IP T K T++
Sbjct: 241 RFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFS 300
Query: 633 --QPHTMKSDSE 642
Q HT+ DSE
Sbjct: 301 GGQHHTVCMDSE 312
Score = 54.8 bits (126), Expect = 1e-06
Identities = 31/94 (32%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Query: 415 AAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN-IDDQWTPQLVTKFLGRKVQSVGCGACHS 473
+ G +H+ +D+ G+ + G +G+LGLG +++ P L+++ V SV CGA
Sbjct: 300 SGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVG 357
Query: 474 VLLTRGGELWACGASVFGQLGTGQRGKASLPVRV 507
+T+ G ++A G QLGTGQ A PV +
Sbjct: 358 YAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEM 391
Score = 54.0 bits (124), Expect = 3e-06
Identities = 42/128 (32%), Positives = 59/128 (46%), Gaps = 13/128 (10%)
Query: 357 GRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVA 415
G+HHT+ + G YS G +G+L L RL + + C A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPT-------LISRLPAVSSVACGA 354
Query: 416 AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTKFL-GRKVQSVGCGACHS 473
+ Y AV GR+ WG G + QLG G +D W+P +++ K L R V SV G H+
Sbjct: 355 SVGY---AVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHT 411
Query: 474 VLLTRGGE 481
VLL + E
Sbjct: 412 VLLVKDKE 419
>CR407693-1|CAG28621.1| 421|Homo sapiens CHC1 protein.
Length = 421
Score = 70.1 bits (164), Expect = 4e-11
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 21/189 (11%)
Query: 428 GRLLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACG 486
G +LT G G GQLGLG N+ ++ P LV+ + V G H+V L++ G++++ G
Sbjct: 35 GLVLTLGQGDVGQLGLGENVMERKKPALVS--IPEDVVQAEAGGMHTVCLSKSGQVYSFG 92
Query: 487 ASVFGQLG--TGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXX 544
+ G LG T G +P +V L E V ++AG H ALT G V++WG+
Sbjct: 93 CNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGS------- 145
Query: 545 XXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTW 604
++ + + + + P V + +V++++G H ++ G +YT
Sbjct: 146 ------FRDNNGVIGLLEPMKKSMVPVQV---QLDVPVVKVASGNDHLVMLTADGDLYTL 196
Query: 605 GLNFDGQLG 613
G GQLG
Sbjct: 197 GCGEQGQLG 205
Score = 61.3 bits (142), Expect = 2e-08
Identities = 55/206 (26%), Positives = 89/206 (43%), Gaps = 11/206 (5%)
Query: 342 PVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXV 400
PV +L V+ VA G H ++LT +G LY+ G GQL +
Sbjct: 165 PVQVQLDVPVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL 224
Query: 401 ------LRVRLAGGAPLVCVA-AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQ 453
L+ R + G A G Y + A+ G + +G + QLG + + PQ
Sbjct: 225 VPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQ 284
Query: 454 LVTKFLGRKVQSVGC--GACHSVLLTRGGELWACGASVFGQLGTGQRGKA-SLPVRVALH 510
+T F VG G H+V + G+ ++ G + +G+LG G+ + S+P ++
Sbjct: 285 NLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRL 344
Query: 511 EPVRALAAGYFHNLALTHKGEVYVWG 536
V ++A G A+T G V+ WG
Sbjct: 345 PAVSSVACGASVGYAVTKDGRVFAWG 370
Score = 57.2 bits (132), Expect = 3e-07
Identities = 71/252 (28%), Positives = 105/252 (41%), Gaps = 28/252 (11%)
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDD--QWTPQLVTKFLGRKVQSVGC 468
+V AG H+ + G++ ++G G LG + + P V L KV V
Sbjct: 69 VVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE--LQEKVVQVSA 126
Query: 469 GACHSVLLTRGGE--LWACGASVFGQLGTGQRGKASL-PVRVALHEPVRALAAGYFHNLA 525
G H+ LT G LW G +G + K S+ PV+V L PV +A+G H +
Sbjct: 127 GDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVM 186
Query: 526 LTHKGEVYVWGASPQ-QVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCV--DTTNVRG-- 580
LT G++Y G Q Q+ L +R L P CV + RG
Sbjct: 187 LTADGDLYTLGCGEQGQLGRVPELFANRGGRQGL------ERLLVPKCVMLKSRGSRGHV 240
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIP---TEVKIRTET----- 632
R G + + I++ G +Y +GL+ QLG+ + IP T K T++
Sbjct: 241 RFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFS 300
Query: 633 --QPHTMKSDSE 642
Q HT+ DSE
Sbjct: 301 GGQHHTVCMDSE 312
Score = 54.8 bits (126), Expect = 1e-06
Identities = 31/94 (32%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Query: 415 AAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN-IDDQWTPQLVTKFLGRKVQSVGCGACHS 473
+ G +H+ +D+ G+ + G +G+LGLG +++ P L+++ V SV CGA
Sbjct: 300 SGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVG 357
Query: 474 VLLTRGGELWACGASVFGQLGTGQRGKASLPVRV 507
+T+ G ++A G QLGTGQ A PV +
Sbjct: 358 YAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEM 391
Score = 54.0 bits (124), Expect = 3e-06
Identities = 42/128 (32%), Positives = 59/128 (46%), Gaps = 13/128 (10%)
Query: 357 GRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVA 415
G+HHT+ + G YS G +G+L L RL + + C A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPT-------LISRLPAVSSVACGA 354
Query: 416 AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTKFL-GRKVQSVGCGACHS 473
+ Y AV GR+ WG G + QLG G +D W+P +++ K L R V SV G H+
Sbjct: 355 SVGY---AVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHT 411
Query: 474 VLLTRGGE 481
VLL + E
Sbjct: 412 VLLVKDKE 419
>BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9
protein.
Length = 979
Score = 70.1 bits (164), Expect = 4e-11
Identities = 44/132 (33%), Positives = 63/132 (47%), Gaps = 9/132 (6%)
Query: 414 VAAGHYHSAAVDAGGRLLTW-----GWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGC 468
V AG+ H A V L TW G +HGQLG G+ P+ V K G+ ++ V C
Sbjct: 374 VCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKHVEKLQGKAIRQVSC 433
Query: 469 GACHSVLLTRGGELWACGASVFGQLG----TGQRGKASLPVRVALHEPVRALAAGYFHNL 524
G +V +T G+L+A G+ +G +G G + + L PV ++ G H +
Sbjct: 434 GDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHVV 493
Query: 525 ALTHKGEVYVWG 536
LT EVY WG
Sbjct: 494 VLTRNKEVYSWG 505
Score = 64.1 bits (149), Expect = 2e-09
Identities = 43/154 (27%), Positives = 74/154 (48%), Gaps = 9/154 (5%)
Query: 346 ELIGRVI-DVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRV 403
+L G+ I V+CG T+ +T+ G LY+ G + +G + +++
Sbjct: 422 KLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEP-------MQL 474
Query: 404 RLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKV 463
P+ V+ G H + + +WG G +G+LGL + +D +TPQ V +
Sbjct: 475 NFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPKALII 534
Query: 464 QSVGCGACHSVLLTRGGELWACGASVFGQLGTGQ 497
+V CG + LLT+ G++ ACG + F +LG Q
Sbjct: 535 VAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQ 568
Score = 55.2 bits (127), Expect = 1e-06
Identities = 51/210 (24%), Positives = 87/210 (41%), Gaps = 8/210 (3%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNI--DDQWTPQLVTKFLGRKVQSVGCGAC 471
V+ G + V G+L +G +G +G+ + + P + FL V+ V CG
Sbjct: 431 VSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDN 490
Query: 472 HSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEP--VRALAAGYFHNLALTHK 529
H V+LTR E+++ G +G+LG P +V + + + A+ G LT
Sbjct: 491 HVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQS 550
Query: 530 GEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGW 589
G+V G + + +H+ Y + +I I+ G
Sbjct: 551 GKVLACGLNEFNKLGLNQCMSGIINHEA--YHE--VPYTTSFTLAKQLSFYKIRTIAPGK 606
Query: 590 HHSCIINNMGSIYTWGLNFDGQLGSGDRKQ 619
H+ I+ G + T+G N GQLG G+ K+
Sbjct: 607 THTAAIDERGRLLTFGCNKCGQLGVGNYKK 636
Score = 50.0 bits (114), Expect = 4e-05
Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 6/149 (4%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXX----XXXVLRVRL 405
++ V CG T +LT++G + + G N F +L +
Sbjct: 534 IVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQ 593
Query: 406 AGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFL-GRKVQ 464
+ +A G H+AA+D GRLLT+G GQLG+GN + L+ L G++V
Sbjct: 594 LSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVI 653
Query: 465 SVGCGACHSVLLTRGGELWACGASVFGQL 493
V CG ++ T ++A G G+L
Sbjct: 654 RVSCGDEFTIAATDDNHIFAWGNGGNGRL 682
Score = 37.5 bits (83), Expect = 0.23
Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 27/104 (25%)
Query: 584 QISAGWHHSCIINNMGSIYTW-----GLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMK 638
Q+ AG H ++ +YTW G GQLG GD+ + P V
Sbjct: 373 QVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKHV------------ 420
Query: 639 SDSEKTTDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTGNTH 682
E ++ V CG DFTV + D+G++Y+ G+ +
Sbjct: 421 ----------EKLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDY 454
>BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 9 protein.
Length = 979
Score = 70.1 bits (164), Expect = 4e-11
Identities = 44/132 (33%), Positives = 63/132 (47%), Gaps = 9/132 (6%)
Query: 414 VAAGHYHSAAVDAGGRLLTW-----GWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGC 468
V AG+ H A V L TW G +HGQLG G+ P+ V K G+ ++ V C
Sbjct: 374 VCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKHVEKLQGKAIRQVSC 433
Query: 469 GACHSVLLTRGGELWACGASVFGQLG----TGQRGKASLPVRVALHEPVRALAAGYFHNL 524
G +V +T G+L+A G+ +G +G G + + L PV ++ G H +
Sbjct: 434 GDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHVV 493
Query: 525 ALTHKGEVYVWG 536
LT EVY WG
Sbjct: 494 VLTRNKEVYSWG 505
Score = 64.1 bits (149), Expect = 2e-09
Identities = 43/154 (27%), Positives = 74/154 (48%), Gaps = 9/154 (5%)
Query: 346 ELIGRVI-DVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRV 403
+L G+ I V+CG T+ +T+ G LY+ G + +G + +++
Sbjct: 422 KLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEP-------MQL 474
Query: 404 RLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKV 463
P+ V+ G H + + +WG G +G+LGL + +D +TPQ V +
Sbjct: 475 NFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPKALII 534
Query: 464 QSVGCGACHSVLLTRGGELWACGASVFGQLGTGQ 497
+V CG + LLT+ G++ ACG + F +LG Q
Sbjct: 535 VAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQ 568
Score = 55.2 bits (127), Expect = 1e-06
Identities = 51/210 (24%), Positives = 87/210 (41%), Gaps = 8/210 (3%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNI--DDQWTPQLVTKFLGRKVQSVGCGAC 471
V+ G + V G+L +G +G +G+ + + P + FL V+ V CG
Sbjct: 431 VSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDN 490
Query: 472 HSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEP--VRALAAGYFHNLALTHK 529
H V+LTR E+++ G +G+LG P +V + + + A+ G LT
Sbjct: 491 HVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQS 550
Query: 530 GEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGW 589
G+V G + + +H+ Y + +I I+ G
Sbjct: 551 GKVLACGLNEFNKLGLNQCMSGIINHEA--YHE--VPYTTSFTLAKQLSFYKIRTIAPGK 606
Query: 590 HHSCIINNMGSIYTWGLNFDGQLGSGDRKQ 619
H+ I+ G + T+G N GQLG G+ K+
Sbjct: 607 THTAAIDERGRLLTFGCNKCGQLGVGNYKK 636
Score = 50.0 bits (114), Expect = 4e-05
Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 6/149 (4%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXX----XXXVLRVRL 405
++ V CG T +LT++G + + G N F +L +
Sbjct: 534 IVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQ 593
Query: 406 AGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFL-GRKVQ 464
+ +A G H+AA+D GRLLT+G GQLG+GN + L+ L G++V
Sbjct: 594 LSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVI 653
Query: 465 SVGCGACHSVLLTRGGELWACGASVFGQL 493
V CG ++ T ++A G G+L
Sbjct: 654 RVSCGDEFTIAATDDNHIFAWGNGGNGRL 682
Score = 37.5 bits (83), Expect = 0.23
Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 27/104 (25%)
Query: 584 QISAGWHHSCIINNMGSIYTW-----GLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMK 638
Q+ AG H ++ +YTW G GQLG GD+ + P V
Sbjct: 373 QVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKHV------------ 420
Query: 639 SDSEKTTDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTGNTH 682
E ++ V CG DFTV + D+G++Y+ G+ +
Sbjct: 421 ----------EKLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDY 454
>BC069198-1|AAH69198.1| 452|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 452
Score = 70.1 bits (164), Expect = 4e-11
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 21/189 (11%)
Query: 428 GRLLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACG 486
G +LT G G GQLGLG N+ ++ P LV+ + V G H+V L++ G++++ G
Sbjct: 66 GLVLTLGQGDVGQLGLGENVMERKKPALVS--IPEDVVQAEAGGMHTVCLSKSGQVYSFG 123
Query: 487 ASVFGQLG--TGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXX 544
+ G LG T G +P +V L E V ++AG H ALT G V++WG+
Sbjct: 124 CNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGS------- 176
Query: 545 XXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTW 604
++ + + + + P V + +V++++G H ++ G +YT
Sbjct: 177 ------FRDNNGVIGLLEPMKKSMVPVQV---QLDVPVVKVASGNDHLVMLTADGDLYTL 227
Query: 605 GLNFDGQLG 613
G GQLG
Sbjct: 228 GCGEQGQLG 236
Score = 61.3 bits (142), Expect = 2e-08
Identities = 55/206 (26%), Positives = 89/206 (43%), Gaps = 11/206 (5%)
Query: 342 PVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXV 400
PV +L V+ VA G H ++LT +G LY+ G GQL +
Sbjct: 196 PVQVQLDVPVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL 255
Query: 401 ------LRVRLAGGAPLVCVA-AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQ 453
L+ R + G A G Y + A+ G + +G + QLG + + PQ
Sbjct: 256 VPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQ 315
Query: 454 LVTKFLGRKVQSVGC--GACHSVLLTRGGELWACGASVFGQLGTGQRGKA-SLPVRVALH 510
+T F VG G H+V + G+ ++ G + +G+LG G+ + S+P ++
Sbjct: 316 NLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRL 375
Query: 511 EPVRALAAGYFHNLALTHKGEVYVWG 536
V ++A G A+T G V+ WG
Sbjct: 376 PAVSSVACGASVGYAVTKDGRVFAWG 401
Score = 57.2 bits (132), Expect = 3e-07
Identities = 71/252 (28%), Positives = 105/252 (41%), Gaps = 28/252 (11%)
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDD--QWTPQLVTKFLGRKVQSVGC 468
+V AG H+ + G++ ++G G LG + + P V L KV V
Sbjct: 100 VVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE--LQEKVVQVSA 157
Query: 469 GACHSVLLTRGGE--LWACGASVFGQLGTGQRGKASL-PVRVALHEPVRALAAGYFHNLA 525
G H+ LT G LW G +G + K S+ PV+V L PV +A+G H +
Sbjct: 158 GDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVM 217
Query: 526 LTHKGEVYVWGASPQ-QVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCV--DTTNVRG-- 580
LT G++Y G Q Q+ L +R L P CV + RG
Sbjct: 218 LTADGDLYTLGCGEQGQLGRVPELFANRGGRQGL------ERLLVPKCVMLKSRGSRGHV 271
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIP---TEVKIRTET----- 632
R G + + I++ G +Y +GL+ QLG+ + IP T K T++
Sbjct: 272 RFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFS 331
Query: 633 --QPHTMKSDSE 642
Q HT+ DSE
Sbjct: 332 GGQHHTVCMDSE 343
Score = 54.8 bits (126), Expect = 1e-06
Identities = 31/94 (32%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Query: 415 AAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN-IDDQWTPQLVTKFLGRKVQSVGCGACHS 473
+ G +H+ +D+ G+ + G +G+LGLG +++ P L+++ V SV CGA
Sbjct: 331 SGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVG 388
Query: 474 VLLTRGGELWACGASVFGQLGTGQRGKASLPVRV 507
+T+ G ++A G QLGTGQ A PV +
Sbjct: 389 YAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEM 422
Score = 54.0 bits (124), Expect = 3e-06
Identities = 42/128 (32%), Positives = 59/128 (46%), Gaps = 13/128 (10%)
Query: 357 GRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVA 415
G+HHT+ + G YS G +G+L L RL + + C A
Sbjct: 333 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPT-------LISRLPAVSSVACGA 385
Query: 416 AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTKFL-GRKVQSVGCGACHS 473
+ Y AV GR+ WG G + QLG G +D W+P +++ K L R V SV G H+
Sbjct: 386 SVGY---AVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHT 442
Query: 474 VLLTRGGE 481
VLL + E
Sbjct: 443 VLLVKDKE 450
>BC036903-1|AAH36903.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 70.1 bits (164), Expect = 4e-11
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 21/189 (11%)
Query: 428 GRLLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACG 486
G +LT G G GQLGLG N+ ++ P LV+ + V G H+V L++ G++++ G
Sbjct: 35 GLVLTLGQGDVGQLGLGENVMERKKPALVS--IPEDVVQAEAGGMHTVCLSKSGQVYSFG 92
Query: 487 ASVFGQLG--TGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXX 544
+ G LG T G +P +V L E V ++AG H ALT G V++WG+
Sbjct: 93 CNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGS------- 145
Query: 545 XXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTW 604
++ + + + + P V + +V++++G H ++ G +YT
Sbjct: 146 ------FRDNNGVIGLLEPMKKSMVPVQV---QLDVPVVKVASGNDHLVMLTADGDLYTL 196
Query: 605 GLNFDGQLG 613
G GQLG
Sbjct: 197 GCGEQGQLG 205
Score = 61.3 bits (142), Expect = 2e-08
Identities = 55/206 (26%), Positives = 89/206 (43%), Gaps = 11/206 (5%)
Query: 342 PVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXV 400
PV +L V+ VA G H ++LT +G LY+ G GQL +
Sbjct: 165 PVQVQLDVPVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL 224
Query: 401 ------LRVRLAGGAPLVCVA-AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQ 453
L+ R + G A G Y + A+ G + +G + QLG + + PQ
Sbjct: 225 VPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQ 284
Query: 454 LVTKFLGRKVQSVGC--GACHSVLLTRGGELWACGASVFGQLGTGQRGKA-SLPVRVALH 510
+T F VG G H+V + G+ ++ G + +G+LG G+ + S+P ++
Sbjct: 285 NLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRL 344
Query: 511 EPVRALAAGYFHNLALTHKGEVYVWG 536
V ++A G A+T G V+ WG
Sbjct: 345 PAVSSVACGASVGYAVTKDGRVFAWG 370
Score = 57.2 bits (132), Expect = 3e-07
Identities = 71/252 (28%), Positives = 105/252 (41%), Gaps = 28/252 (11%)
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDD--QWTPQLVTKFLGRKVQSVGC 468
+V AG H+ + G++ ++G G LG + + P V L KV V
Sbjct: 69 VVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE--LQEKVVQVSA 126
Query: 469 GACHSVLLTRGGE--LWACGASVFGQLGTGQRGKASL-PVRVALHEPVRALAAGYFHNLA 525
G H+ LT G LW G +G + K S+ PV+V L PV +A+G H +
Sbjct: 127 GDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVM 186
Query: 526 LTHKGEVYVWGASPQ-QVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCV--DTTNVRG-- 580
LT G++Y G Q Q+ L +R L P CV + RG
Sbjct: 187 LTADGDLYTLGCGEQGQLGRVPELFANRGGRQGL------ERLLVPKCVMLKSRGSRGHV 240
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIP---TEVKIRTET----- 632
R G + + I++ G +Y +GL+ QLG+ + IP T K T++
Sbjct: 241 RFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFS 300
Query: 633 --QPHTMKSDSE 642
Q HT+ DSE
Sbjct: 301 GGQHHTVCMDSE 312
Score = 54.8 bits (126), Expect = 1e-06
Identities = 31/94 (32%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Query: 415 AAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN-IDDQWTPQLVTKFLGRKVQSVGCGACHS 473
+ G +H+ +D+ G+ + G +G+LGLG +++ P L+++ V SV CGA
Sbjct: 300 SGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVG 357
Query: 474 VLLTRGGELWACGASVFGQLGTGQRGKASLPVRV 507
+T+ G ++A G QLGTGQ A PV +
Sbjct: 358 YAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEM 391
Score = 54.0 bits (124), Expect = 3e-06
Identities = 42/128 (32%), Positives = 59/128 (46%), Gaps = 13/128 (10%)
Query: 357 GRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVA 415
G+HHT+ + G YS G +G+L L RL + + C A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPT-------LISRLPAVSSVACGA 354
Query: 416 AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTKFL-GRKVQSVGCGACHS 473
+ Y AV GR+ WG G + QLG G +D W+P +++ K L R V SV G H+
Sbjct: 355 SVGY---AVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHT 411
Query: 474 VLLTRGGE 481
VLL + E
Sbjct: 412 VLLVKDKE 419
>BC010067-1|AAH10067.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 70.1 bits (164), Expect = 4e-11
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 21/189 (11%)
Query: 428 GRLLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACG 486
G +LT G G GQLGLG N+ ++ P LV+ + V G H+V L++ G++++ G
Sbjct: 35 GLVLTLGQGDVGQLGLGENVMERKKPALVS--IPEDVVQAEAGGMHTVCLSKSGQVYSFG 92
Query: 487 ASVFGQLG--TGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXX 544
+ G LG T G +P +V L E V ++AG H ALT G V++WG+
Sbjct: 93 CNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGS------- 145
Query: 545 XXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTW 604
++ + + + + P V + +V++++G H ++ G +YT
Sbjct: 146 ------FRDNNGVIGLLEPMKKSMVPVQV---QLDVPVVKVASGNDHLVMLTADGDLYTL 196
Query: 605 GLNFDGQLG 613
G GQLG
Sbjct: 197 GCGEQGQLG 205
Score = 61.3 bits (142), Expect = 2e-08
Identities = 55/206 (26%), Positives = 89/206 (43%), Gaps = 11/206 (5%)
Query: 342 PVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXV 400
PV +L V+ VA G H ++LT +G LY+ G GQL +
Sbjct: 165 PVQVQLDVPVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL 224
Query: 401 ------LRVRLAGGAPLVCVA-AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQ 453
L+ R + G A G Y + A+ G + +G + QLG + + PQ
Sbjct: 225 VPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQ 284
Query: 454 LVTKFLGRKVQSVGC--GACHSVLLTRGGELWACGASVFGQLGTGQRGKA-SLPVRVALH 510
+T F VG G H+V + G+ ++ G + +G+LG G+ + S+P ++
Sbjct: 285 NLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRL 344
Query: 511 EPVRALAAGYFHNLALTHKGEVYVWG 536
V ++A G A+T G V+ WG
Sbjct: 345 PAVSSVACGASVGYAVTKDGRVFAWG 370
Score = 57.2 bits (132), Expect = 3e-07
Identities = 71/252 (28%), Positives = 105/252 (41%), Gaps = 28/252 (11%)
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDD--QWTPQLVTKFLGRKVQSVGC 468
+V AG H+ + G++ ++G G LG + + P V L KV V
Sbjct: 69 VVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE--LQEKVVQVSA 126
Query: 469 GACHSVLLTRGGE--LWACGASVFGQLGTGQRGKASL-PVRVALHEPVRALAAGYFHNLA 525
G H+ LT G LW G +G + K S+ PV+V L PV +A+G H +
Sbjct: 127 GDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVM 186
Query: 526 LTHKGEVYVWGASPQ-QVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCV--DTTNVRG-- 580
LT G++Y G Q Q+ L +R L P CV + RG
Sbjct: 187 LTADGDLYTLGCGEQGQLGRVPELFANRGGRQGL------ERLLVPKCVMLKSRGSRGHV 240
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIP---TEVKIRTET----- 632
R G + + I++ G +Y +GL+ QLG+ + IP T K T++
Sbjct: 241 RFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFS 300
Query: 633 --QPHTMKSDSE 642
Q HT+ DSE
Sbjct: 301 GGQHHTVCMDSE 312
Score = 54.8 bits (126), Expect = 1e-06
Identities = 31/94 (32%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Query: 415 AAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN-IDDQWTPQLVTKFLGRKVQSVGCGACHS 473
+ G +H+ +D+ G+ + G +G+LGLG +++ P L+++ V SV CGA
Sbjct: 300 SGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVG 357
Query: 474 VLLTRGGELWACGASVFGQLGTGQRGKASLPVRV 507
+T+ G ++A G QLGTGQ A PV +
Sbjct: 358 YAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEM 391
Score = 54.0 bits (124), Expect = 3e-06
Identities = 42/128 (32%), Positives = 59/128 (46%), Gaps = 13/128 (10%)
Query: 357 GRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVA 415
G+HHT+ + G YS G +G+L L RL + + C A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPT-------LISRLPAVSSVACGA 354
Query: 416 AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTKFL-GRKVQSVGCGACHS 473
+ Y AV GR+ WG G + QLG G +D W+P +++ K L R V SV G H+
Sbjct: 355 SVGY---AVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHT 411
Query: 474 VLLTRGGE 481
VLL + E
Sbjct: 412 VLLVKDKE 419
>BC007300-1|AAH07300.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 70.1 bits (164), Expect = 4e-11
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 21/189 (11%)
Query: 428 GRLLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACG 486
G +LT G G GQLGLG N+ ++ P LV+ + V G H+V L++ G++++ G
Sbjct: 35 GLVLTLGQGDVGQLGLGENVMERKKPALVS--IPEDVVQAEAGGMHTVCLSKSGQVYSFG 92
Query: 487 ASVFGQLG--TGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXX 544
+ G LG T G +P +V L E V ++AG H ALT G V++WG+
Sbjct: 93 CNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGS------- 145
Query: 545 XXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTW 604
++ + + + + P V + +V++++G H ++ G +YT
Sbjct: 146 ------FRDNNGVIGLLEPMKKSMVPVQV---QLDVPVVKVASGNDHLVMLTADGDLYTL 196
Query: 605 GLNFDGQLG 613
G GQLG
Sbjct: 197 GCGEQGQLG 205
Score = 61.3 bits (142), Expect = 2e-08
Identities = 55/206 (26%), Positives = 89/206 (43%), Gaps = 11/206 (5%)
Query: 342 PVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXV 400
PV +L V+ VA G H ++LT +G LY+ G GQL +
Sbjct: 165 PVQVQLDVPVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL 224
Query: 401 ------LRVRLAGGAPLVCVA-AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQ 453
L+ R + G A G Y + A+ G + +G + QLG + + PQ
Sbjct: 225 VPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQ 284
Query: 454 LVTKFLGRKVQSVGC--GACHSVLLTRGGELWACGASVFGQLGTGQRGKA-SLPVRVALH 510
+T F VG G H+V + G+ ++ G + +G+LG G+ + S+P ++
Sbjct: 285 NLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRL 344
Query: 511 EPVRALAAGYFHNLALTHKGEVYVWG 536
V ++A G A+T G V+ WG
Sbjct: 345 PAVSSVACGASVGYAVTKDGRVFAWG 370
Score = 57.2 bits (132), Expect = 3e-07
Identities = 71/252 (28%), Positives = 105/252 (41%), Gaps = 28/252 (11%)
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDD--QWTPQLVTKFLGRKVQSVGC 468
+V AG H+ + G++ ++G G LG + + P V L KV V
Sbjct: 69 VVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE--LQEKVVQVSA 126
Query: 469 GACHSVLLTRGGE--LWACGASVFGQLGTGQRGKASL-PVRVALHEPVRALAAGYFHNLA 525
G H+ LT G LW G +G + K S+ PV+V L PV +A+G H +
Sbjct: 127 GDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVM 186
Query: 526 LTHKGEVYVWGASPQ-QVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCV--DTTNVRG-- 580
LT G++Y G Q Q+ L +R L P CV + RG
Sbjct: 187 LTADGDLYTLGCGEQGQLGRVPELFANRGGRQGL------ERLLVPKCVMLKSRGSRGHV 240
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIP---TEVKIRTET----- 632
R G + + I++ G +Y +GL+ QLG+ + IP T K T++
Sbjct: 241 RFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFS 300
Query: 633 --QPHTMKSDSE 642
Q HT+ DSE
Sbjct: 301 GGQHHTVCMDSE 312
Score = 54.8 bits (126), Expect = 1e-06
Identities = 31/94 (32%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Query: 415 AAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN-IDDQWTPQLVTKFLGRKVQSVGCGACHS 473
+ G +H+ +D+ G+ + G +G+LGLG +++ P L+++ V SV CGA
Sbjct: 300 SGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVG 357
Query: 474 VLLTRGGELWACGASVFGQLGTGQRGKASLPVRV 507
+T+ G ++A G QLGTGQ A PV +
Sbjct: 358 YAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEM 391
Score = 54.0 bits (124), Expect = 3e-06
Identities = 42/128 (32%), Positives = 59/128 (46%), Gaps = 13/128 (10%)
Query: 357 GRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVA 415
G+HHT+ + G YS G +G+L L RL + + C A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPT-------LISRLPAVSSVACGA 354
Query: 416 AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTKFL-GRKVQSVGCGACHS 473
+ Y AV GR+ WG G + QLG G +D W+P +++ K L R V SV G H+
Sbjct: 355 SVGY---AVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHT 411
Query: 474 VLLTRGGE 481
VLL + E
Sbjct: 412 VLLVKDKE 419
>AL513497-2|CAI22287.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 70.1 bits (164), Expect = 4e-11
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 21/189 (11%)
Query: 428 GRLLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACG 486
G +LT G G GQLGLG N+ ++ P LV+ + V G H+V L++ G++++ G
Sbjct: 35 GLVLTLGQGDVGQLGLGENVMERKKPALVS--IPEDVVQAEAGGMHTVCLSKSGQVYSFG 92
Query: 487 ASVFGQLG--TGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXX 544
+ G LG T G +P +V L E V ++AG H ALT G V++WG+
Sbjct: 93 CNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGS------- 145
Query: 545 XXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTW 604
++ + + + + P V + +V++++G H ++ G +YT
Sbjct: 146 ------FRDNNGVIGLLEPMKKSMVPVQV---QLDVPVVKVASGNDHLVMLTADGDLYTL 196
Query: 605 GLNFDGQLG 613
G GQLG
Sbjct: 197 GCGEQGQLG 205
Score = 61.3 bits (142), Expect = 2e-08
Identities = 55/206 (26%), Positives = 89/206 (43%), Gaps = 11/206 (5%)
Query: 342 PVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXV 400
PV +L V+ VA G H ++LT +G LY+ G GQL +
Sbjct: 165 PVQVQLDVPVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL 224
Query: 401 ------LRVRLAGGAPLVCVA-AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQ 453
L+ R + G A G Y + A+ G + +G + QLG + + PQ
Sbjct: 225 VPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQ 284
Query: 454 LVTKFLGRKVQSVGC--GACHSVLLTRGGELWACGASVFGQLGTGQRGKA-SLPVRVALH 510
+T F VG G H+V + G+ ++ G + +G+LG G+ + S+P ++
Sbjct: 285 NLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRL 344
Query: 511 EPVRALAAGYFHNLALTHKGEVYVWG 536
V ++A G A+T G V+ WG
Sbjct: 345 PAVSSVACGASVGYAVTKDGRVFAWG 370
Score = 57.2 bits (132), Expect = 3e-07
Identities = 71/252 (28%), Positives = 105/252 (41%), Gaps = 28/252 (11%)
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDD--QWTPQLVTKFLGRKVQSVGC 468
+V AG H+ + G++ ++G G LG + + P V L KV V
Sbjct: 69 VVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE--LQEKVVQVSA 126
Query: 469 GACHSVLLTRGGE--LWACGASVFGQLGTGQRGKASL-PVRVALHEPVRALAAGYFHNLA 525
G H+ LT G LW G +G + K S+ PV+V L PV +A+G H +
Sbjct: 127 GDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVM 186
Query: 526 LTHKGEVYVWGASPQ-QVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCV--DTTNVRG-- 580
LT G++Y G Q Q+ L +R L P CV + RG
Sbjct: 187 LTADGDLYTLGCGEQGQLGRVPELFANRGGRQGL------ERLLVPKCVMLKSRGSRGHV 240
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIP---TEVKIRTET----- 632
R G + + I++ G +Y +GL+ QLG+ + IP T K T++
Sbjct: 241 RFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFS 300
Query: 633 --QPHTMKSDSE 642
Q HT+ DSE
Sbjct: 301 GGQHHTVCMDSE 312
Score = 54.8 bits (126), Expect = 1e-06
Identities = 31/94 (32%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Query: 415 AAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN-IDDQWTPQLVTKFLGRKVQSVGCGACHS 473
+ G +H+ +D+ G+ + G +G+LGLG +++ P L+++ V SV CGA
Sbjct: 300 SGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVG 357
Query: 474 VLLTRGGELWACGASVFGQLGTGQRGKASLPVRV 507
+T+ G ++A G QLGTGQ A PV +
Sbjct: 358 YAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEM 391
Score = 54.0 bits (124), Expect = 3e-06
Identities = 42/128 (32%), Positives = 59/128 (46%), Gaps = 13/128 (10%)
Query: 357 GRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVA 415
G+HHT+ + G YS G +G+L L RL + + C A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPT-------LISRLPAVSSVACGA 354
Query: 416 AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTKFL-GRKVQSVGCGACHS 473
+ Y AV GR+ WG G + QLG G +D W+P +++ K L R V SV G H+
Sbjct: 355 SVGY---AVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHT 411
Query: 474 VLLTRGGE 481
VLL + E
Sbjct: 412 VLLVKDKE 419
>AF498924-1|AAM21072.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 70.1 bits (164), Expect = 4e-11
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 21/189 (11%)
Query: 428 GRLLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACG 486
G +LT G G GQLGLG N+ ++ P LV+ + V G H+V L++ G++++ G
Sbjct: 35 GLVLTLGQGDVGQLGLGENVMERKKPALVS--IPEDVVQAEAGGMHTVCLSKSGQVYSFG 92
Query: 487 ASVFGQLG--TGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXX 544
+ G LG T G +P +V L E V ++AG H ALT G V++WG+
Sbjct: 93 CNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGS------- 145
Query: 545 XXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTW 604
++ + + + + P V + +V++++G H ++ G +YT
Sbjct: 146 ------FRDNNGVIGLLEPMKKSMVPVQV---QLDVPVVKVASGNDHLVMLTADGDLYTL 196
Query: 605 GLNFDGQLG 613
G GQLG
Sbjct: 197 GCGEQGQLG 205
Score = 61.3 bits (142), Expect = 2e-08
Identities = 55/206 (26%), Positives = 89/206 (43%), Gaps = 11/206 (5%)
Query: 342 PVNTELIGRVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXV 400
PV +L V+ VA G H ++LT +G LY+ G GQL +
Sbjct: 165 PVQVQLDVPVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL 224
Query: 401 ------LRVRLAGGAPLVCVA-AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQ 453
L+ R + G A G Y + A+ G + +G + QLG + + PQ
Sbjct: 225 VPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQ 284
Query: 454 LVTKFLGRKVQSVGC--GACHSVLLTRGGELWACGASVFGQLGTGQRGKA-SLPVRVALH 510
+T F VG G H+V + G+ ++ G + +G+LG G+ + S+P ++
Sbjct: 285 NLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRL 344
Query: 511 EPVRALAAGYFHNLALTHKGEVYVWG 536
V ++A G A+T G V+ WG
Sbjct: 345 PAVSSVACGASVGYAVTKDGRVFAWG 370
Score = 57.2 bits (132), Expect = 3e-07
Identities = 71/252 (28%), Positives = 105/252 (41%), Gaps = 28/252 (11%)
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDD--QWTPQLVTKFLGRKVQSVGC 468
+V AG H+ + G++ ++G G LG + + P V L KV V
Sbjct: 69 VVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE--LQEKVVQVSA 126
Query: 469 GACHSVLLTRGGE--LWACGASVFGQLGTGQRGKASL-PVRVALHEPVRALAAGYFHNLA 525
G H+ LT G LW G +G + K S+ PV+V L PV +A+G H +
Sbjct: 127 GDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVM 186
Query: 526 LTHKGEVYVWGASPQ-QVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCV--DTTNVRG-- 580
LT G++Y G Q Q+ L +R L P CV + RG
Sbjct: 187 LTADGDLYTLGCGEQGQLGRVPELFANRGGRQGL------ERLLVPKCVMLKSRGSRGHV 240
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIP---TEVKIRTET----- 632
R G + + I++ G +Y +GL+ QLG+ + IP T K T++
Sbjct: 241 RFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFS 300
Query: 633 --QPHTMKSDSE 642
Q HT+ DSE
Sbjct: 301 GGQHHTVCMDSE 312
Score = 54.8 bits (126), Expect = 1e-06
Identities = 31/94 (32%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Query: 415 AAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN-IDDQWTPQLVTKFLGRKVQSVGCGACHS 473
+ G +H+ +D+ G+ + G +G+LGLG +++ P L+++ V SV CGA
Sbjct: 300 SGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVG 357
Query: 474 VLLTRGGELWACGASVFGQLGTGQRGKASLPVRV 507
+T+ G ++A G QLGTGQ A PV +
Sbjct: 358 YAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEM 391
Score = 54.0 bits (124), Expect = 3e-06
Identities = 42/128 (32%), Positives = 59/128 (46%), Gaps = 13/128 (10%)
Query: 357 GRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLVCVA 415
G+HHT+ + G YS G +G+L L RL + + C A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPT-------LISRLPAVSSVACGA 354
Query: 416 AGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTKFL-GRKVQSVGCGACHS 473
+ Y AV GR+ WG G + QLG G +D W+P +++ K L R V SV G H+
Sbjct: 355 SVGY---AVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHT 411
Query: 474 VLLTRGGE 481
VLL + E
Sbjct: 412 VLLVKDKE 419
>AC007055-4|AAD31939.1| 414|Homo sapiens protein ( Homo sapiens
chromosome 14 clone BAC 201F1 map 14q24.3, complete
sequence. ).
Length = 414
Score = 70.1 bits (164), Expect = 4e-11
Identities = 44/132 (33%), Positives = 63/132 (47%), Gaps = 9/132 (6%)
Query: 414 VAAGHYHSAAVDAGGRLLTW-----GWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGC 468
V AG+ H A V L TW G +HGQLG G+ P+ V K G+ ++ V C
Sbjct: 44 VCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKHVEKLQGKAIRQVSC 103
Query: 469 GACHSVLLTRGGELWACGASVFGQLG----TGQRGKASLPVRVALHEPVRALAAGYFHNL 524
G +V +T G+L+A G+ +G +G G + + L PV ++ G H +
Sbjct: 104 GDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHVV 163
Query: 525 ALTHKGEVYVWG 536
LT EVY WG
Sbjct: 164 VLTRNKEVYSWG 175
Score = 64.1 bits (149), Expect = 2e-09
Identities = 43/154 (27%), Positives = 74/154 (48%), Gaps = 9/154 (5%)
Query: 346 ELIGRVI-DVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRV 403
+L G+ I V+CG T+ +T+ G LY+ G + +G + +++
Sbjct: 92 KLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEP-------MQL 144
Query: 404 RLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKV 463
P+ V+ G H + + +WG G +G+LGL + +D +TPQ V +
Sbjct: 145 NFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPKALII 204
Query: 464 QSVGCGACHSVLLTRGGELWACGASVFGQLGTGQ 497
+V CG + LLT+ G++ ACG + F +LG Q
Sbjct: 205 VAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQ 238
Score = 55.2 bits (127), Expect = 1e-06
Identities = 51/210 (24%), Positives = 87/210 (41%), Gaps = 8/210 (3%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNI--DDQWTPQLVTKFLGRKVQSVGCGAC 471
V+ G + V G+L +G +G +G+ + + P + FL V+ V CG
Sbjct: 101 VSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDN 160
Query: 472 HSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEP--VRALAAGYFHNLALTHK 529
H V+LTR E+++ G +G+LG P +V + + + A+ G LT
Sbjct: 161 HVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQS 220
Query: 530 GEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGW 589
G+V G + + +H+ Y + +I I+ G
Sbjct: 221 GKVLACGLNEFNKLGLNQCMSGIINHEA--YHE--VPYTTSFTLAKQLSFYKIRTIAPGK 276
Query: 590 HHSCIINNMGSIYTWGLNFDGQLGSGDRKQ 619
H+ I+ G + T+G N GQLG G+ K+
Sbjct: 277 THTAAIDERGRLLTFGCNKCGQLGVGNYKK 306
Score = 50.0 bits (114), Expect = 4e-05
Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 6/149 (4%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXX----XXXVLRVRL 405
++ V CG T +LT++G + + G N F +L +
Sbjct: 204 IVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQ 263
Query: 406 AGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFL-GRKVQ 464
+ +A G H+AA+D GRLLT+G GQLG+GN + L+ L G++V
Sbjct: 264 LSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVI 323
Query: 465 SVGCGACHSVLLTRGGELWACGASVFGQL 493
V CG ++ T ++A G G+L
Sbjct: 324 RVSCGDEFTIAATDDNHIFAWGNGGNGRL 352
Score = 37.5 bits (83), Expect = 0.23
Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 27/104 (25%)
Query: 584 QISAGWHHSCIINNMGSIYTW-----GLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMK 638
Q+ AG H ++ +YTW G GQLG GD+ + P V
Sbjct: 43 QVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKHV------------ 90
Query: 639 SDSEKTTDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTGNTH 682
E ++ V CG DFTV + D+G++Y+ G+ +
Sbjct: 91 ----------EKLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDY 124
>AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERCC1
protein.
Length = 979
Score = 69.7 bits (163), Expect = 5e-11
Identities = 44/132 (33%), Positives = 62/132 (46%), Gaps = 9/132 (6%)
Query: 414 VAAGHYHSAAVDAGGRLLTW-----GWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGC 468
V AG+ H A V L TW G +HGQLG G+ P+ V K G+ + V C
Sbjct: 374 VCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKHVEKLQGKAIHQVSC 433
Query: 469 GACHSVLLTRGGELWACGASVFGQLG----TGQRGKASLPVRVALHEPVRALAAGYFHNL 524
G +V +T G+L+A G+ +G +G G + + L PV ++ G H +
Sbjct: 434 GDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHVV 493
Query: 525 ALTHKGEVYVWG 536
LT EVY WG
Sbjct: 494 VLTRNKEVYSWG 505
Score = 64.1 bits (149), Expect = 2e-09
Identities = 43/154 (27%), Positives = 74/154 (48%), Gaps = 9/154 (5%)
Query: 346 ELIGRVI-DVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRV 403
+L G+ I V+CG T+ +T+ G LY+ G + +G + +++
Sbjct: 422 KLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEP-------MQL 474
Query: 404 RLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKV 463
P+ V+ G H + + +WG G +G+LGL + +D +TPQ V +
Sbjct: 475 NFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPKALII 534
Query: 464 QSVGCGACHSVLLTRGGELWACGASVFGQLGTGQ 497
+V CG + LLT+ G++ ACG + F +LG Q
Sbjct: 535 VAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQ 568
Score = 55.2 bits (127), Expect = 1e-06
Identities = 51/210 (24%), Positives = 87/210 (41%), Gaps = 8/210 (3%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNI--DDQWTPQLVTKFLGRKVQSVGCGAC 471
V+ G + V G+L +G +G +G+ + + P + FL V+ V CG
Sbjct: 431 VSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDN 490
Query: 472 HSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEP--VRALAAGYFHNLALTHK 529
H V+LTR E+++ G +G+LG P +V + + + A+ G LT
Sbjct: 491 HVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQS 550
Query: 530 GEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGW 589
G+V G + + +H+ Y + +I I+ G
Sbjct: 551 GKVLACGLNEFNKLGLNQCMSGIINHEA--YHE--VPYTTSFTLAKQLSFYKIRTIAPGK 606
Query: 590 HHSCIINNMGSIYTWGLNFDGQLGSGDRKQ 619
H+ I+ G + T+G N GQLG G+ K+
Sbjct: 607 THTAAIDERGRLLTFGCNKCGQLGVGNYKK 636
Score = 50.0 bits (114), Expect = 4e-05
Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 6/149 (4%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXX----XXXVLRVRL 405
++ V CG T +LT++G + + G N F +L +
Sbjct: 534 IVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQ 593
Query: 406 AGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFL-GRKVQ 464
+ +A G H+AA+D GRLLT+G GQLG+GN + L+ L G++V
Sbjct: 594 LSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVI 653
Query: 465 SVGCGACHSVLLTRGGELWACGASVFGQL 493
V CG ++ T ++A G G+L
Sbjct: 654 RVSCGDEFTIAATDDNHIFAWGNGGNGRL 682
Score = 37.1 bits (82), Expect = 0.31
Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 27/104 (25%)
Query: 584 QISAGWHHSCIINNMGSIYTW-----GLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMK 638
Q+ AG H ++ +YTW G GQLG GD+ + P V
Sbjct: 373 QVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKHV------------ 420
Query: 639 SDSEKTTDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTGNTH 682
E ++ V CG DFTV + D+G++Y+ G+ +
Sbjct: 421 ----------EKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDY 454
>AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek8
protein.
Length = 979
Score = 69.7 bits (163), Expect = 5e-11
Identities = 44/132 (33%), Positives = 62/132 (46%), Gaps = 9/132 (6%)
Query: 414 VAAGHYHSAAVDAGGRLLTW-----GWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGC 468
V AG+ H A V L TW G +HGQLG G+ P+ V K G+ + V C
Sbjct: 374 VCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKHVEKLQGKAIHQVSC 433
Query: 469 GACHSVLLTRGGELWACGASVFGQLG----TGQRGKASLPVRVALHEPVRALAAGYFHNL 524
G +V +T G+L+A G+ +G +G G + + L PV ++ G H +
Sbjct: 434 GDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHVV 493
Query: 525 ALTHKGEVYVWG 536
LT EVY WG
Sbjct: 494 VLTRNKEVYSWG 505
Score = 64.1 bits (149), Expect = 2e-09
Identities = 43/154 (27%), Positives = 74/154 (48%), Gaps = 9/154 (5%)
Query: 346 ELIGRVI-DVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRV 403
+L G+ I V+CG T+ +T+ G LY+ G + +G + +++
Sbjct: 422 KLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEP-------MQL 474
Query: 404 RLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKV 463
P+ V+ G H + + +WG G +G+LGL + +D +TPQ V +
Sbjct: 475 NFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPKALII 534
Query: 464 QSVGCGACHSVLLTRGGELWACGASVFGQLGTGQ 497
+V CG + LLT+ G++ ACG + F +LG Q
Sbjct: 535 VAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQ 568
Score = 55.2 bits (127), Expect = 1e-06
Identities = 51/210 (24%), Positives = 87/210 (41%), Gaps = 8/210 (3%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNI--DDQWTPQLVTKFLGRKVQSVGCGAC 471
V+ G + V G+L +G +G +G+ + + P + FL V+ V CG
Sbjct: 431 VSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDN 490
Query: 472 HSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEP--VRALAAGYFHNLALTHK 529
H V+LTR E+++ G +G+LG P +V + + + A+ G LT
Sbjct: 491 HVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQS 550
Query: 530 GEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGW 589
G+V G + + +H+ Y + +I I+ G
Sbjct: 551 GKVLACGLNEFNKLGLNQCMSGIINHEA--YHE--VPYTTSFTLAKQLSFYKIRTIAPGK 606
Query: 590 HHSCIINNMGSIYTWGLNFDGQLGSGDRKQ 619
H+ I+ G + T+G N GQLG G+ K+
Sbjct: 607 THTAAIDERGRLLTFGCNKCGQLGVGNYKK 636
Score = 50.0 bits (114), Expect = 4e-05
Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 6/149 (4%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXX----XXXVLRVRL 405
++ V CG T +LT++G + + G N F +L +
Sbjct: 534 IVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQ 593
Query: 406 AGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFL-GRKVQ 464
+ +A G H+AA+D GRLLT+G GQLG+GN + L+ L G++V
Sbjct: 594 LSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVI 653
Query: 465 SVGCGACHSVLLTRGGELWACGASVFGQL 493
V CG ++ T ++A G G+L
Sbjct: 654 RVSCGDEFTIAATDDNHIFAWGNGGNGRL 682
Score = 37.1 bits (82), Expect = 0.31
Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 27/104 (25%)
Query: 584 QISAGWHHSCIINNMGSIYTW-----GLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMK 638
Q+ AG H ++ +YTW G GQLG GD+ + P V
Sbjct: 373 QVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKHV------------ 420
Query: 639 SDSEKTTDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTGNTH 682
E ++ V CG DFTV + D+G++Y+ G+ +
Sbjct: 421 ----------EKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDY 454
>AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein.
Length = 1011
Score = 69.7 bits (163), Expect = 5e-11
Identities = 44/132 (33%), Positives = 62/132 (46%), Gaps = 9/132 (6%)
Query: 414 VAAGHYHSAAVDAGGRLLTW-----GWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGC 468
V AG+ H A V L TW G +HGQLG G+ P+ V K G+ + V C
Sbjct: 406 VCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKHVEKLQGKAIHQVSC 465
Query: 469 GACHSVLLTRGGELWACGASVFGQLG----TGQRGKASLPVRVALHEPVRALAAGYFHNL 524
G +V +T G+L+A G+ +G +G G + + L PV ++ G H +
Sbjct: 466 GDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHVV 525
Query: 525 ALTHKGEVYVWG 536
LT EVY WG
Sbjct: 526 VLTRNKEVYSWG 537
Score = 64.1 bits (149), Expect = 2e-09
Identities = 43/154 (27%), Positives = 74/154 (48%), Gaps = 9/154 (5%)
Query: 346 ELIGRVI-DVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRV 403
+L G+ I V+CG T+ +T+ G LY+ G + +G + +++
Sbjct: 454 KLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEP-------MQL 506
Query: 404 RLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKV 463
P+ V+ G H + + +WG G +G+LGL + +D +TPQ V +
Sbjct: 507 NFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPKALII 566
Query: 464 QSVGCGACHSVLLTRGGELWACGASVFGQLGTGQ 497
+V CG + LLT+ G++ ACG + F +LG Q
Sbjct: 567 VAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQ 600
Score = 55.2 bits (127), Expect = 1e-06
Identities = 51/210 (24%), Positives = 87/210 (41%), Gaps = 8/210 (3%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNI--DDQWTPQLVTKFLGRKVQSVGCGAC 471
V+ G + V G+L +G +G +G+ + + P + FL V+ V CG
Sbjct: 463 VSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDN 522
Query: 472 HSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEP--VRALAAGYFHNLALTHK 529
H V+LTR E+++ G +G+LG P +V + + + A+ G LT
Sbjct: 523 HVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQS 582
Query: 530 GEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGW 589
G+V G + + +H+ Y + +I I+ G
Sbjct: 583 GKVLACGLNEFNKLGLNQCMSGIINHEA--YHE--VPYTTSFTLAKQLSFYKIRTIAPGK 638
Query: 590 HHSCIINNMGSIYTWGLNFDGQLGSGDRKQ 619
H+ I+ G + T+G N GQLG G+ K+
Sbjct: 639 THTAAIDERGRLLTFGCNKCGQLGVGNYKK 668
Score = 50.0 bits (114), Expect = 4e-05
Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 6/149 (4%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXX----XXXVLRVRL 405
++ V CG T +LT++G + + G N F +L +
Sbjct: 566 IVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQ 625
Query: 406 AGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFL-GRKVQ 464
+ +A G H+AA+D GRLLT+G GQLG+GN + L+ L G++V
Sbjct: 626 LSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVI 685
Query: 465 SVGCGACHSVLLTRGGELWACGASVFGQL 493
V CG ++ T ++A G G+L
Sbjct: 686 RVSCGDEFTIAATDDNHIFAWGNGGNGRL 714
Score = 37.1 bits (82), Expect = 0.31
Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 27/104 (25%)
Query: 584 QISAGWHHSCIINNMGSIYTW-----GLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMK 638
Q+ AG H ++ +YTW G GQLG GD+ + P V
Sbjct: 405 QVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKHV------------ 452
Query: 639 SDSEKTTDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTGNTH 682
E ++ V CG DFTV + D+G++Y+ G+ +
Sbjct: 453 ----------EKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDY 486
>AK092403-1|BAC03879.1| 184|Homo sapiens protein ( Homo sapiens
cDNA FLJ35084 fis, clone PLACE6005482. ).
Length = 184
Score = 68.9 bits (161), Expect = 8e-11
Identities = 44/132 (33%), Positives = 66/132 (50%), Gaps = 6/132 (4%)
Query: 411 LVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG-NIDDQWTPQLVTKFLGRKVQSVGCG 469
++ V+ GHYHS A+ ++ +WG HGQLGLG Q +PQ V G + V G
Sbjct: 8 IIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAG 67
Query: 470 ACHSVLLTRGGELWACGASVFGQLGTGQRG---KASLPVRV-ALHE-PVRALAAGYFHNL 524
HS L+ G + G++ GQL R +++ P+ V AL V ++ G H
Sbjct: 68 GAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTA 127
Query: 525 ALTHKGEVYVWG 536
LT G+V+ +G
Sbjct: 128 VLTQDGKVFTFG 139
Score = 66.1 bits (154), Expect = 6e-10
Identities = 49/149 (32%), Positives = 70/149 (46%), Gaps = 12/149 (8%)
Query: 350 RVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
++I V+CG +H+L L+++ ++S G N+ GQL RVR G
Sbjct: 7 KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQ--------RVRSLEG 58
Query: 409 APLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLG--NIDDQWT-PQLVTKFLGRKVQS 465
PL VAAG HS A+ G WG GQL L N+ Q P V V
Sbjct: 59 IPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVY 118
Query: 466 VGCGACHSVLLTRGGELWACGASVFGQLG 494
+ CG H+ +LT+ G+++ G + GQLG
Sbjct: 119 ISCGDAHTAVLTQDGKVFTFGDNRSGQLG 147
Score = 56.4 bits (130), Expect = 5e-07
Identities = 45/155 (29%), Positives = 72/155 (46%), Gaps = 17/155 (10%)
Query: 462 KVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQR-GKASLPVRVALHE--PVRALAA 518
K+ V CG HS+ L++ ++++ G + GQLG G+ + P RV E P+ +AA
Sbjct: 7 KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAA 66
Query: 519 GYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNV 578
G H+ AL+ G + WG++ S +P + P V
Sbjct: 67 GGAHSFALSLCGTSFGWGSN--------SAGQLALSGRNVPVQSNK-----PLSVGALKN 113
Query: 579 RGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLG 613
G +V IS G H+ ++ G ++T+G N GQLG
Sbjct: 114 LG-VVYISCGDAHTAVLTQDGKVFTFGDNRSGQLG 147
Score = 39.1 bits (87), Expect = 0.077
Identities = 14/35 (40%), Positives = 23/35 (65%)
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSG 615
+I+Q+S G +HS ++ +++WG N GQLG G
Sbjct: 7 KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLG 41
Score = 36.3 bits (80), Expect = 0.54
Identities = 32/117 (27%), Positives = 48/117 (41%), Gaps = 8/117 (6%)
Query: 354 VACGRHHTLILTENGL-YSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLV 412
VA G H+ L+ G + G N+ GQL L V +V
Sbjct: 64 VAAGGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKP------LSVGALKNLGVV 117
Query: 413 CVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCG 469
++ G H+A + G++ T+G GQLG ++ PQLV + G V + CG
Sbjct: 118 YISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDG-LVSQIDCG 173
>BC004933-1|AAH04933.1| 351|Homo sapiens RCC2 protein protein.
Length = 351
Score = 67.3 bits (157), Expect = 3e-10
Identities = 47/207 (22%), Positives = 91/207 (43%), Gaps = 11/207 (5%)
Query: 433 WGWG--VHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVF 490
W WG GQLG G+ P+L+ + S CG H++ LT G ++A G +
Sbjct: 1 WSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKM 60
Query: 491 GQLGTG-QRGKASLPVRVALH-EPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXXX 548
GQLG G Q P ++ + +P+ +A G ++ + KG +Y +G
Sbjct: 61 GQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSD 120
Query: 549 XXXEPSSPTLPFHDDNDRYLAPSCVDTTN------VRGRIVQ-ISAGWHHSCIINNMGSI 601
+ + + + ++ T V +V+ ++ G +H+ ++++ +
Sbjct: 121 GKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRV 180
Query: 602 YTWGLNFDGQLGSGDRKQIQIPTEVKI 628
++WG G+LG ++K +P VK+
Sbjct: 181 FSWGFGGYGRLGHAEQKDEMVPRLVKL 207
Score = 62.5 bits (145), Expect = 7e-09
Identities = 57/217 (26%), Positives = 96/217 (44%), Gaps = 38/217 (17%)
Query: 351 VIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGA 409
++ ACGR+HTL LTE G +++ G+N GQL + G
Sbjct: 33 IVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQI---------MYNGQ 83
Query: 410 PLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGN------------IDDQWTPQLVTK 457
P+ +A G S +D G L ++G +GQLG + D + P+ V
Sbjct: 84 PITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAI 143
Query: 458 FLGRK------------VQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPV 505
F+ + V+ V CGA H+++L +++ G +G+LG ++ +P
Sbjct: 144 FIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPR 203
Query: 506 RVALHE-PVRA---LAAGYFHNLALTHKGEVYVWGAS 538
V L + P R + AGY + A++ G ++ WGA+
Sbjct: 204 LVKLFDFPGRGASQIYAGYTCSFAVSEVGGLFFWGAT 240
Score = 55.6 bits (128), Expect = 8e-07
Identities = 51/201 (25%), Positives = 81/201 (40%), Gaps = 21/201 (10%)
Query: 483 WACGASVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQ 540
W+ G + GQLG G + P + HE + + A G H LALT G V+ +G +
Sbjct: 1 WSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKM 60
Query: 541 QVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGS 600
PS + ++ I +++ G S I++ G+
Sbjct: 61 GQLGLGNQTDAVPSPAQIMYNGQP-----------------ITKMACGAEFSMIMDCKGN 103
Query: 601 IYTWGLNFDGQLG-SGDRKQIQIPTEVKIRTETQPHTMKSDSEKTTDADENMEFNTKAL- 658
+Y++G GQLG + D K I ++ E P + EKT D N
Sbjct: 104 LYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRD 163
Query: 659 VGCGGDFTVYIDDDGRIYSTG 679
V CG + T+ +D R++S G
Sbjct: 164 VACGANHTLVLDSQKRVFSWG 184
Score = 44.8 bits (101), Expect = 0.002
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 7/128 (5%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVT--KFLGRKVQSVGCGAC 471
VA G H+ +D+ R+ +WG+G +G+LG D+ P+LV F GR + G
Sbjct: 164 VACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYT 223
Query: 472 HSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHEPVRALAAGYFHNLALTHKGE 531
S ++ G L+ GA+ + T KA V+ +R+LA G + +
Sbjct: 224 CSFAVSEVGGLFFWGATNTSREST-MYPKA---VQDLCGWRIRSLACGKSSIIVAADEST 279
Query: 532 VYVWGASP 539
+ WG SP
Sbjct: 280 I-SWGPSP 286
>BC040929-1|AAH40929.1| 651|Homo sapiens HERC1 protein protein.
Length = 651
Score = 61.7 bits (143), Expect = 1e-08
Identities = 39/128 (30%), Positives = 62/128 (48%), Gaps = 3/128 (2%)
Query: 433 WGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQ 492
+G G +G+LGLGN + +PQ + G ++ V CG SV LT+ G ++ G
Sbjct: 1 FGDGDYGKLGLGNSTAKSSPQKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIG 60
Query: 493 LGTGQRGKASLPVRVALHEPV--RALAAGYFHNLALTHKGEVYVWGASPQ-QVXXXXXXX 549
L G+ + P ++ + V +A G H LAL G+VY WG++ + Q+
Sbjct: 61 LPEGRARNHNRPQQIPVLAGVIIEDVAVGAEHTLALASNGDVYAWGSNSEGQLGLGHTNH 120
Query: 550 XXEPSSPT 557
EP+ T
Sbjct: 121 VREPTLVT 128
Score = 54.8 bits (126), Expect = 1e-06
Identities = 38/125 (30%), Positives = 56/125 (44%), Gaps = 10/125 (8%)
Query: 354 VACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGGAPLV 412
VACG ++ LT++G +Y TFGQ ++ + G +
Sbjct: 34 VACGTQFSVALTKDGHVY-----TFGQ----DRLIGLPEGRARNHNRPQQIPVLAGVIIE 84
Query: 413 CVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACH 472
VA G H+ A+ + G + WG GQLGLG+ + P LVT G+ V+ + G CH
Sbjct: 85 DVAVGAEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVTGLQGKNVRQISAGRCH 144
Query: 473 SVLLT 477
S T
Sbjct: 145 SAAWT 149
Score = 39.9 bits (89), Expect = 0.044
Identities = 16/45 (35%), Positives = 25/45 (55%)
Query: 582 IVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEV 626
I ++ G H+ + + G +Y WG N +GQLG G ++ PT V
Sbjct: 83 IEDVAVGAEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLV 127
Score = 33.1 bits (72), Expect = 5.0
Identities = 19/36 (52%), Positives = 23/36 (63%), Gaps = 2/36 (5%)
Query: 347 LIGRVI-DVACGRHHTLILTENG-LYSAGDNTFGQL 380
L G +I DVA G HTL L NG +Y+ G N+ GQL
Sbjct: 78 LAGVIIEDVAVGAEHTLALASNGDVYAWGSNSEGQL 113
>BC040695-1|AAH40695.1| 358|Homo sapiens WBSCR16 protein protein.
Length = 358
Score = 59.7 bits (138), Expect = 5e-08
Identities = 50/159 (31%), Positives = 76/159 (47%), Gaps = 9/159 (5%)
Query: 340 STPVNTELIGRVIDVACGRHHTLILTEN-GLYSAGDNTFGQLXXXXXXXXXXXXXXXXXX 398
S P++ RV+ V+CGR H+L+LT+ G++S G+N++GQ
Sbjct: 165 SLPLDRPQETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHR--- 221
Query: 399 XVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTP-QLVTK 457
V R++ G +V VA G HS + G + + GWG GQ GLG+ + +P +L
Sbjct: 222 -VHRMQDFDGQ-VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGD 279
Query: 458 FLGRKVQSVGC-GACHSVLLTRGGELWACGASVFGQLGT 495
G V V G C + GG L+ G S + QL +
Sbjct: 280 LAGVNVIQVATYGDCCLAVSADGG-LFGWGNSEYLQLAS 317
Score = 44.4 bits (100), Expect = 0.002
Identities = 36/133 (27%), Positives = 61/133 (45%), Gaps = 9/133 (6%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQL-----VTKFLGRKVQSVGC 468
V+ G HS + + + G +GQ G ++++ + + F G+ VQ V C
Sbjct: 179 VSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQ-VAC 237
Query: 469 GACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALH-EPVRALAAGYFHN--LA 525
G HS+ LT GE+++CG GQ G G S P ++ V + + + LA
Sbjct: 238 GQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDCCLA 297
Query: 526 LTHKGEVYVWGAS 538
++ G ++ WG S
Sbjct: 298 VSADGGLFGWGNS 310
Score = 39.1 bits (87), Expect = 0.077
Identities = 16/47 (34%), Positives = 26/47 (55%)
Query: 580 GRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEV 626
G++VQ++ G HS + + G +Y+ G DGQ G G PT++
Sbjct: 230 GQVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKL 276
>AY650034-1|AAV66580.1| 110|Homo sapiens HECT and RCC1 containing
protein 4 isoform 4 protein.
Length = 110
Score = 58.0 bits (134), Expect = 2e-07
Identities = 27/67 (40%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Query: 430 LLTWGWGVHGQLGLGNIDDQWT--PQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGA 487
+L WG GQLGLG ID++ P+ F+ ++V+ VGCG H+V + G ++ CG
Sbjct: 1 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC 60
Query: 488 SVFGQLG 494
+ GQLG
Sbjct: 61 NDLGQLG 67
Score = 33.5 bits (73), Expect = 3.8
Identities = 15/32 (46%), Positives = 21/32 (65%), Gaps = 1/32 (3%)
Query: 350 RVIDVACGRHHTLILTENG-LYSAGDNTFGQL 380
RV DV CG HT+ + ++G +Y+ G N GQL
Sbjct: 35 RVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQL 66
Score = 33.1 bits (72), Expect = 5.0
Identities = 15/34 (44%), Positives = 23/34 (67%), Gaps = 1/34 (2%)
Query: 659 VGCGGDFTVYIDDDGRIYSTGNTHL-QISNEKTK 691
VGCG TV++ DDG +Y+ G L Q+ +EK++
Sbjct: 39 VGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKSR 72
>AY650032-1|AAV66578.1| 117|Homo sapiens HECT and RCC1 containing
protein 4 isoform 2 protein.
Length = 117
Score = 58.0 bits (134), Expect = 2e-07
Identities = 27/67 (40%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Query: 430 LLTWGWGVHGQLGLGNIDDQWT--PQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGA 487
+L WG GQLGLG ID++ P+ F+ ++V+ VGCG H+V + G ++ CG
Sbjct: 1 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC 60
Query: 488 SVFGQLG 494
+ GQLG
Sbjct: 61 NDLGQLG 67
Score = 36.7 bits (81), Expect = 0.41
Identities = 24/77 (31%), Positives = 42/77 (54%), Gaps = 3/77 (3%)
Query: 659 VGCGGDFTVYIDDDGRIYSTGNTHL-QISNEKTKGGNRVIMMKTTKRVIKIPASRTNH-K 716
VGCG TV++ DDG +Y+ G L Q+ +EK++ ++ + R+ ++ H
Sbjct: 39 VGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEILKVCQISRLYRLLVVTIIHLH 98
Query: 717 FLFQPVAAV-DMLSSAN 732
FL Q ++V D ++ AN
Sbjct: 99 FLKQVKSSVGDRINMAN 115
Score = 33.5 bits (73), Expect = 3.8
Identities = 15/32 (46%), Positives = 21/32 (65%), Gaps = 1/32 (3%)
Query: 350 RVIDVACGRHHTLILTENG-LYSAGDNTFGQL 380
RV DV CG HT+ + ++G +Y+ G N GQL
Sbjct: 35 RVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQL 66
>AL359257-2|CAI39759.1| 4640|Homo sapiens AC001226.5 protein.
Length = 4640
Score = 57.2 bits (132), Expect = 3e-07
Identities = 30/83 (36%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 412 VCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGAC 471
V V+ G +HS + G + T+G+G HGQLG G+++ + P LV G Q V G+
Sbjct: 905 VQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPSTQ-VTAGSN 963
Query: 472 HSVLLTRGGELWACGASVFGQLG 494
H+ +L G+++ G+ GQLG
Sbjct: 964 HTAVLLMDGQVFTFGSFSKGQLG 986
Score = 47.2 bits (107), Expect = 3e-04
Identities = 29/78 (37%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 461 RKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV-ALHEPVRALAAG 519
R VQ V CG HSV+L G+++ G GQLG G P V AL P + AG
Sbjct: 903 RAVQ-VSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPSTQVTAG 961
Query: 520 YFHNLALTHKGEVYVWGA 537
H L G+V+ +G+
Sbjct: 962 SNHTAVLLMDGQVFTFGS 979
Score = 47.2 bits (107), Expect = 3e-04
Identities = 21/47 (44%), Positives = 28/47 (59%)
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
R VQ+S G+HHS ++ G +YT+G GQLG GD PT V+
Sbjct: 903 RAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQ 949
Score = 41.1 bits (92), Expect = 0.019
Identities = 40/134 (29%), Positives = 58/134 (43%), Gaps = 19/134 (14%)
Query: 350 RVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
R + V+CG HH+++L ENG +Y+ G GQL L L G
Sbjct: 903 RAVQVSCGFHHSVVLMENGDVYTFGYGQHGQL--------GHGDVNSRGCPTLVQALPG- 953
Query: 409 APLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNID-DQWT------PQLVTKFLGR 461
P V AG H+A + G++ T+G GQLG +D W P + +K+ GR
Sbjct: 954 -PSTQVTAGSNHTAVLLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKY-GR 1011
Query: 462 KVQSVGCGACHSVL 475
K +G + L
Sbjct: 1012 KATWIGASGDQTFL 1025
Score = 35.5 bits (78), Expect = 0.95
Identities = 14/39 (35%), Positives = 26/39 (66%), Gaps = 1/39 (2%)
Query: 576 TNVRGRIV-QISAGWHHSCIINNMGSIYTWGLNFDGQLG 613
T+++G V Q++ G H+C++ G ++T+G+N GQ G
Sbjct: 638 TDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCG 676
Score = 34.7 bits (76), Expect = 1.7
Identities = 16/41 (39%), Positives = 21/41 (51%)
Query: 454 LVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLG 494
LVT G V V G H+ +L + GE+W G + GQ G
Sbjct: 636 LVTDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCG 676
>AL159158-1|CAI16842.1| 4640|Homo sapiens AC001226.5 protein.
Length = 4640
Score = 57.2 bits (132), Expect = 3e-07
Identities = 30/83 (36%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 412 VCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGAC 471
V V+ G +HS + G + T+G+G HGQLG G+++ + P LV G Q V G+
Sbjct: 905 VQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPSTQ-VTAGSN 963
Query: 472 HSVLLTRGGELWACGASVFGQLG 494
H+ +L G+++ G+ GQLG
Sbjct: 964 HTAVLLMDGQVFTFGSFSKGQLG 986
Score = 47.2 bits (107), Expect = 3e-04
Identities = 29/78 (37%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 461 RKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV-ALHEPVRALAAG 519
R VQ V CG HSV+L G+++ G GQLG G P V AL P + AG
Sbjct: 903 RAVQ-VSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPSTQVTAG 961
Query: 520 YFHNLALTHKGEVYVWGA 537
H L G+V+ +G+
Sbjct: 962 SNHTAVLLMDGQVFTFGS 979
Score = 47.2 bits (107), Expect = 3e-04
Identities = 21/47 (44%), Positives = 28/47 (59%)
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
R VQ+S G+HHS ++ G +YT+G GQLG GD PT V+
Sbjct: 903 RAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQ 949
Score = 41.1 bits (92), Expect = 0.019
Identities = 40/134 (29%), Positives = 58/134 (43%), Gaps = 19/134 (14%)
Query: 350 RVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
R + V+CG HH+++L ENG +Y+ G GQL L L G
Sbjct: 903 RAVQVSCGFHHSVVLMENGDVYTFGYGQHGQL--------GHGDVNSRGCPTLVQALPG- 953
Query: 409 APLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNID-DQWT------PQLVTKFLGR 461
P V AG H+A + G++ T+G GQLG +D W P + +K+ GR
Sbjct: 954 -PSTQVTAGSNHTAVLLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKY-GR 1011
Query: 462 KVQSVGCGACHSVL 475
K +G + L
Sbjct: 1012 KATWIGASGDQTFL 1025
Score = 35.5 bits (78), Expect = 0.95
Identities = 14/39 (35%), Positives = 26/39 (66%), Gaps = 1/39 (2%)
Query: 576 TNVRGRIV-QISAGWHHSCIINNMGSIYTWGLNFDGQLG 613
T+++G V Q++ G H+C++ G ++T+G+N GQ G
Sbjct: 638 TDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCG 676
Score = 34.7 bits (76), Expect = 1.7
Identities = 16/41 (39%), Positives = 21/41 (51%)
Query: 454 LVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLG 494
LVT G V V G H+ +L + GE+W G + GQ G
Sbjct: 636 LVTDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCG 676
>AL159154-1|CAH73736.1| 4640|Homo sapiens AC001226.5 protein.
Length = 4640
Score = 57.2 bits (132), Expect = 3e-07
Identities = 30/83 (36%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 412 VCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGAC 471
V V+ G +HS + G + T+G+G HGQLG G+++ + P LV G Q V G+
Sbjct: 905 VQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPSTQ-VTAGSN 963
Query: 472 HSVLLTRGGELWACGASVFGQLG 494
H+ +L G+++ G+ GQLG
Sbjct: 964 HTAVLLMDGQVFTFGSFSKGQLG 986
Score = 47.2 bits (107), Expect = 3e-04
Identities = 29/78 (37%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 461 RKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV-ALHEPVRALAAG 519
R VQ V CG HSV+L G+++ G GQLG G P V AL P + AG
Sbjct: 903 RAVQ-VSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPSTQVTAG 961
Query: 520 YFHNLALTHKGEVYVWGA 537
H L G+V+ +G+
Sbjct: 962 SNHTAVLLMDGQVFTFGS 979
Score = 47.2 bits (107), Expect = 3e-04
Identities = 21/47 (44%), Positives = 28/47 (59%)
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
R VQ+S G+HHS ++ G +YT+G GQLG GD PT V+
Sbjct: 903 RAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQ 949
Score = 41.1 bits (92), Expect = 0.019
Identities = 40/134 (29%), Positives = 58/134 (43%), Gaps = 19/134 (14%)
Query: 350 RVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
R + V+CG HH+++L ENG +Y+ G GQL L L G
Sbjct: 903 RAVQVSCGFHHSVVLMENGDVYTFGYGQHGQL--------GHGDVNSRGCPTLVQALPG- 953
Query: 409 APLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNID-DQWT------PQLVTKFLGR 461
P V AG H+A + G++ T+G GQLG +D W P + +K+ GR
Sbjct: 954 -PSTQVTAGSNHTAVLLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKY-GR 1011
Query: 462 KVQSVGCGACHSVL 475
K +G + L
Sbjct: 1012 KATWIGASGDQTFL 1025
Score = 35.5 bits (78), Expect = 0.95
Identities = 14/39 (35%), Positives = 26/39 (66%), Gaps = 1/39 (2%)
Query: 576 TNVRGRIV-QISAGWHHSCIINNMGSIYTWGLNFDGQLG 613
T+++G V Q++ G H+C++ G ++T+G+N GQ G
Sbjct: 638 TDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCG 676
Score = 34.7 bits (76), Expect = 1.7
Identities = 16/41 (39%), Positives = 21/41 (51%)
Query: 454 LVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLG 494
LVT G V V G H+ +L + GE+W G + GQ G
Sbjct: 636 LVTDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCG 676
>AF075587-1|AAC39928.1| 4641|Homo sapiens protein associated with
Myc protein.
Length = 4641
Score = 57.2 bits (132), Expect = 3e-07
Identities = 30/83 (36%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 412 VCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGAC 471
V V+ G +HS + G + T+G+G HGQLG G+++ + P LV G Q V G+
Sbjct: 905 VQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPSTQ-VTAGSN 963
Query: 472 HSVLLTRGGELWACGASVFGQLG 494
H+ +L G+++ G+ GQLG
Sbjct: 964 HTAVLLMDGQVFTFGSFSKGQLG 986
Score = 47.2 bits (107), Expect = 3e-04
Identities = 29/78 (37%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 461 RKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV-ALHEPVRALAAG 519
R VQ V CG HSV+L G+++ G GQLG G P V AL P + AG
Sbjct: 903 RAVQ-VSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPSTQVTAG 961
Query: 520 YFHNLALTHKGEVYVWGA 537
H L G+V+ +G+
Sbjct: 962 SNHTAVLLMDGQVFTFGS 979
Score = 47.2 bits (107), Expect = 3e-04
Identities = 21/47 (44%), Positives = 28/47 (59%)
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVK 627
R VQ+S G+HHS ++ G +YT+G GQLG GD PT V+
Sbjct: 903 RAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQ 949
Score = 41.1 bits (92), Expect = 0.019
Identities = 40/134 (29%), Positives = 58/134 (43%), Gaps = 19/134 (14%)
Query: 350 RVIDVACGRHHTLILTENG-LYSAGDNTFGQLXXXXXXXXXXXXXXXXXXXVLRVRLAGG 408
R + V+CG HH+++L ENG +Y+ G GQL L L G
Sbjct: 903 RAVQVSCGFHHSVVLMENGDVYTFGYGQHGQL--------GHGDVNSRGCPTLVQALPG- 953
Query: 409 APLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNID-DQWT------PQLVTKFLGR 461
P V AG H+A + G++ T+G GQLG +D W P + +K+ GR
Sbjct: 954 -PSTQVTAGSNHTAVLLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKY-GR 1011
Query: 462 KVQSVGCGACHSVL 475
K +G + L
Sbjct: 1012 KATWIGASGDQTFL 1025
Score = 35.5 bits (78), Expect = 0.95
Identities = 14/39 (35%), Positives = 26/39 (66%), Gaps = 1/39 (2%)
Query: 576 TNVRGRIV-QISAGWHHSCIINNMGSIYTWGLNFDGQLG 613
T+++G V Q++ G H+C++ G ++T+G+N GQ G
Sbjct: 638 TDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCG 676
Score = 34.7 bits (76), Expect = 1.7
Identities = 16/41 (39%), Positives = 21/41 (51%)
Query: 454 LVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLG 494
LVT G V V G H+ +L + GE+W G + GQ G
Sbjct: 636 LVTDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCG 676
>AC004460-2|AAC06339.1| 371|Homo sapiens WUGSC:H_DJ1086D14.2
protein.
Length = 371
Score = 56.4 bits (130), Expect = 5e-07
Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 2/111 (1%)
Query: 428 GRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGA 487
G + +WG G G+LG G + PQ + + G+ V + CGA + LT+ G +W G
Sbjct: 1 GLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFLLALTKSGVVWTWGK 60
Query: 488 SVFGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLALTHKGEVYVWG 536
+ +LG P V + + +A G H LA+ G+VY WG
Sbjct: 61 GDYFRLGHRSDVHVRKPQVVEGLRGKKIVHVAVGAQHCLAVMDSGQVYAWG 111
Score = 52.8 bits (121), Expect = 6e-06
Identities = 28/70 (40%), Positives = 34/70 (48%)
Query: 408 GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVG 467
G +V VA G H AV G++ WG HGQ G G P LV G+K+ V
Sbjct: 85 GKKIVHVAVGAQHCLAVMDSGQVYAWGDNDHGQQGNGTTTVNRKPMLVQGLEGQKIMCVA 144
Query: 468 CGACHSVLLT 477
CG+ HSV T
Sbjct: 145 CGSSHSVAWT 154
Score = 46.8 bits (106), Expect = 4e-04
Identities = 35/119 (29%), Positives = 56/119 (47%), Gaps = 3/119 (2%)
Query: 412 VC-VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGA 470
VC + G A+ G + TWG G + +LG + PQ+V G+K+ V GA
Sbjct: 36 VCQIECGAQFLLALTKSGVVWTWGKGDYFRLGHRSDVHVRKPQVVEGLRGKKIVHVAVGA 95
Query: 471 CHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV-ALH-EPVRALAAGYFHNLALT 527
H + + G+++A G + GQ G G P+ V L + + +A G H++A T
Sbjct: 96 QHCLAVMDSGQVYAWGDNDHGQQGNGTTTVNRKPMLVQGLEGQKIMCVACGSSHSVAWT 154
Score = 37.9 bits (84), Expect = 0.18
Identities = 36/139 (25%), Positives = 56/139 (40%), Gaps = 21/139 (15%)
Query: 480 GELWACGASVFGQLGTGQRGKASLPVRVAL--HEPVRALAAGYFHNLALTHKGEVYVWGA 537
G +++ G FG+LG G ++P + + V + G LALT G V+ WG
Sbjct: 1 GLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFLLALTKSGVVWTWGK 60
Query: 538 SPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGR-IVQISAGWHHSCIIN 596
H + P V+ +RG+ IV ++ G H +
Sbjct: 61 GDYFRLG----------------HRSDVHVRKPQVVE--GLRGKKIVHVAVGAQHCLAVM 102
Query: 597 NMGSIYTWGLNFDGQLGSG 615
+ G +Y WG N GQ G+G
Sbjct: 103 DSGQVYAWGDNDHGQQGNG 121
>BC029174-1|AAH29174.1| 812|Homo sapiens ALS2 protein protein.
Length = 812
Score = 55.2 bits (127), Expect = 1e-06
Identities = 45/150 (30%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Query: 332 GNARVMMASTPVNTELIGR-VIDVACGRHHTLILTENGL-YSAGDNTFGQLXXXXXXXXX 389
G + +S + L+G+ VI VA G H+ +T+NG+ Y G+N+ GQ
Sbjct: 73 GPVEICPSSPILENALVGQYVITVATGSFHSGAVTDNGVAYMCGENSAGQCAVANQQYVP 132
Query: 390 XXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQ 449
LA ++ +A G H+ A+ + W WG QLGL
Sbjct: 133 EPNPVSIADSEASPLLA--VRILQLACGEEHTLALSISREI--WAWGTGCQLGLITTAFP 188
Query: 450 WT-PQLVTKFLGRKVQSVGCGACHSVLLTR 478
T PQ V GR V V CGA HS+ L +
Sbjct: 189 VTKPQKVEHLAGRVVLQVACGAFHSLALVQ 218
Score = 50.8 bits (116), Expect = 2e-05
Identities = 31/97 (31%), Positives = 53/97 (54%), Gaps = 3/97 (3%)
Query: 432 TWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFG 491
TWG G GQLG G++ + P V G++V + G HS+ LT ++++ G++ FG
Sbjct: 530 TWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFG 589
Query: 492 QLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLAL 526
QLG ++P +++ V ++AAG ++L L
Sbjct: 590 QLGHSD-FPTTVPRLAKISSENGVWSIAAGRDYSLFL 625
Score = 43.2 bits (97), Expect = 0.005
Identities = 34/106 (32%), Positives = 52/106 (49%), Gaps = 7/106 (6%)
Query: 440 QLGLGNIDDQWTPQLVTKFLGRKVQSVGC-----GACHSVLLTRGGELWACGASVFGQLG 494
+L L + Q +P+L+ K K ++V G ++L + E+W G GQLG
Sbjct: 481 RLSLPGLLSQVSPRLLRKAARVKTRTVVLTPTYSGEADALLPSLRTEVWTWGKGKEGQLG 540
Query: 495 TGQRGKASLPVRVALHE--PVRALAAGYFHNLALTHKGEVYVWGAS 538
G P+ V + V L AG +H+LALT K +VY WG++
Sbjct: 541 HGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSN 586
Score = 41.5 bits (93), Expect = 0.014
Identities = 38/143 (26%), Positives = 62/143 (43%), Gaps = 11/143 (7%)
Query: 407 GGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSV 466
GG ++ A G H + G + ++G + + G I +P L +G+ V +V
Sbjct: 39 GGKTVLQAALGVKHGVLLTEDGEVYSFGT-LPWRSGPVEICPS-SPILENALVGQYVITV 96
Query: 467 GCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHE----PVRA-----LA 517
G+ HS +T G + CG + GQ + P V++ + P+ A LA
Sbjct: 97 ATGSFHSGAVTDNGVAYMCGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLA 156
Query: 518 AGYFHNLALTHKGEVYVWGASPQ 540
G H LAL+ E++ WG Q
Sbjct: 157 CGEEHTLALSISREIWAWGTGCQ 179
Score = 41.1 bits (92), Expect = 0.019
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 2/71 (2%)
Query: 561 HDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQI 620
H D L P CV + + ++ + AG +HS + +Y+WG N GQLG D
Sbjct: 541 HGDVLPRLQPLCVKCLDGK-EVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSD-FPT 598
Query: 621 QIPTEVKIRTE 631
+P KI +E
Sbjct: 599 TVPRLAKISSE 609
Score = 40.3 bits (90), Expect = 0.033
Identities = 37/156 (23%), Positives = 65/156 (41%), Gaps = 12/156 (7%)
Query: 451 TPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALH 510
TP+ + + G+ V G H VLLT GE+++ G + + + +
Sbjct: 31 TPERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEICPSSPILENALVG 90
Query: 511 EPVRALAAGYFHNLALTHKGEVYVWGA-SPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLA 569
+ V +A G FH+ A+T G Y+ G S Q EP+ ++ D +
Sbjct: 91 QYVITVATGSFHSGAVTDNGVAYMCGENSAGQCAVANQQYVPEPNPVSIA-----DSEAS 145
Query: 570 PSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWG 605
P + RI+Q++ G H+ ++ I+ WG
Sbjct: 146 PL------LAVRILQLACGEEHTLALSISREIWAWG 175
Score = 37.5 bits (83), Expect = 0.23
Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Query: 401 LRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLG 460
L V+ G ++ + AG YHS A+ A ++ +WG GQLG + P+L
Sbjct: 551 LCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTT-VPRLAKISSE 609
Query: 461 RKVQSVGCGACHSVLL 476
V S+ G +S+ L
Sbjct: 610 NGVWSIAAGRDYSLFL 625
Score = 32.3 bits (70), Expect = 8.8
Identities = 16/31 (51%), Positives = 22/31 (70%), Gaps = 1/31 (3%)
Query: 351 VIDVACGRHHTLILT-ENGLYSAGDNTFGQL 380
VI + G +H+L LT ++ +YS G NTFGQL
Sbjct: 561 VIHLEAGGYHSLALTAKSQVYSWGSNTFGQL 591
>BC071576-1|AAH71576.1| 1237|Homo sapiens ALS2 protein protein.
Length = 1237
Score = 54.0 bits (124), Expect = 3e-06
Identities = 45/150 (30%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Query: 332 GNARVMMASTPVNTELIGR-VIDVACGRHHTLILTENGL-YSAGDNTFGQLXXXXXXXXX 389
G + +S + L+G+ VI VA G H+ +T+NG+ Y G+N+ GQ
Sbjct: 73 GPVEICPSSPILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVP 132
Query: 390 XXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQ 449
LA ++ +A G H+ A+ + W WG QLGL
Sbjct: 133 EPNPVSIADSEASPLLA--VRILQLACGEEHTLALSISREI--WAWGTGCQLGLITTAFP 188
Query: 450 WT-PQLVTKFLGRKVQSVGCGACHSVLLTR 478
T PQ V GR V V CGA HS+ L +
Sbjct: 189 VTKPQKVEHLAGRVVLQVACGAFHSLALVQ 218
Score = 50.8 bits (116), Expect = 2e-05
Identities = 31/97 (31%), Positives = 53/97 (54%), Gaps = 3/97 (3%)
Query: 432 TWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFG 491
TWG G GQLG G++ + P V G++V + G HS+ LT ++++ G++ FG
Sbjct: 530 TWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFG 589
Query: 492 QLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLAL 526
QLG ++P +++ V ++AAG ++L L
Sbjct: 590 QLGHSD-FPTTVPRLAKISSENGVWSIAAGRDYSLFL 625
Score = 45.6 bits (103), Expect = 9e-04
Identities = 38/156 (24%), Positives = 66/156 (42%), Gaps = 12/156 (7%)
Query: 451 TPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALH 510
TP+ + + G+ V G H VLLT GE+++ G + + + +
Sbjct: 31 TPERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEICPSSPILENALVG 90
Query: 511 EPVRALAAGYFHNLALTHKGEVYVWGA-SPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLA 569
+ V +A G FH+ A+T G Y+WG S Q EP+ ++ D +
Sbjct: 91 QYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIA-----DSEAS 145
Query: 570 PSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWG 605
P + RI+Q++ G H+ ++ I+ WG
Sbjct: 146 PL------LAVRILQLACGEEHTLALSISREIWAWG 175
Score = 45.6 bits (103), Expect = 9e-04
Identities = 36/129 (27%), Positives = 53/129 (41%), Gaps = 12/129 (9%)
Query: 408 GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQ---------LVTKF 458
G ++ VA G +HS AV G WG GQ + N Q+ P+ +
Sbjct: 90 GQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVAN--QQYVPEPNPVSIADSEASPL 147
Query: 459 LGRKVQSVGCGACHSVLLTRGGELWACGASV-FGQLGTGQRGKASLPVRVALHEPVRALA 517
L ++ + CG H++ L+ E+WA G G + T V V +A
Sbjct: 148 LAVRILQLACGEEHTLALSISREIWAWGTGCQLGLITTAFPVTKPQKVEHLAGRVVLQVA 207
Query: 518 AGYFHNLAL 526
G FH+LAL
Sbjct: 208 CGAFHSLAL 216
Score = 42.3 bits (95), Expect = 0.008
Identities = 34/106 (32%), Positives = 52/106 (49%), Gaps = 7/106 (6%)
Query: 440 QLGLGNIDDQWTPQLVTKFLGRKVQSVGC-----GACHSVLLTRGGELWACGASVFGQLG 494
+L L + Q +P+L+ K K ++V G ++L + E+W G GQLG
Sbjct: 481 RLSLPGLLSQVSPRLLRKAARVKTRTVVLTPTYSGEADALLPSLRIEVWTWGKGKEGQLG 540
Query: 495 TGQRGKASLPVRVALHE--PVRALAAGYFHNLALTHKGEVYVWGAS 538
G P+ V + V L AG +H+LALT K +VY WG++
Sbjct: 541 HGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSN 586
Score = 41.1 bits (92), Expect = 0.019
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 2/71 (2%)
Query: 561 HDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQI 620
H D L P CV + + ++ + AG +HS + +Y+WG N GQLG D
Sbjct: 541 HGDVLPRLQPLCVKCLDGK-EVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSD-FPT 598
Query: 621 QIPTEVKIRTE 631
+P KI +E
Sbjct: 599 TVPRLAKISSE 609
Score = 37.5 bits (83), Expect = 0.23
Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Query: 401 LRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLG 460
L V+ G ++ + AG YHS A+ A ++ +WG GQLG + P+L
Sbjct: 551 LCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTT-VPRLAKISSE 609
Query: 461 RKVQSVGCGACHSVLL 476
V S+ G +S+ L
Sbjct: 610 NGVWSIAAGRDYSLFL 625
Score = 37.1 bits (82), Expect = 0.31
Identities = 37/143 (25%), Positives = 61/143 (42%), Gaps = 11/143 (7%)
Query: 407 GGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSV 466
GG ++ A G H + G + ++G + + G I +P L +G+ V +V
Sbjct: 39 GGKTVLQAALGVKHGVLLTEDGEVYSFGT-LPWRSGPVEICPS-SPILENALVGQYVITV 96
Query: 467 GCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHE----PVRA-----LA 517
G+ HS +T G + G + GQ + P V++ + P+ A LA
Sbjct: 97 ATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLA 156
Query: 518 AGYFHNLALTHKGEVYVWGASPQ 540
G H LAL+ E++ WG Q
Sbjct: 157 CGEEHTLALSISREIWAWGTGCQ 179
Score = 35.5 bits (78), Expect = 0.95
Identities = 32/119 (26%), Positives = 47/119 (39%), Gaps = 20/119 (16%)
Query: 517 AAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTT 576
A G H + LT GEVY +G P + PSSP L +
Sbjct: 47 ALGVKHGVLLTEDGEVYSFGTLPWRSGPVEIC----PSSPIL---------------ENA 87
Query: 577 NVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIR-TETQP 634
V ++ ++ G HS + + G Y WG N GQ +++ + P V I +E P
Sbjct: 88 LVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASP 146
Score = 32.3 bits (70), Expect = 8.8
Identities = 16/31 (51%), Positives = 22/31 (70%), Gaps = 1/31 (3%)
Query: 351 VIDVACGRHHTLILT-ENGLYSAGDNTFGQL 380
VI + G +H+L LT ++ +YS G NTFGQL
Sbjct: 561 VIHLEAGGYHSLALTAKSQVYSWGSNTFGQL 591
>AK023024-1|BAB14362.1| 396|Homo sapiens protein ( Homo sapiens
cDNA FLJ12962 fis, clone NT2RP2005694, weakly similar to
X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR. ).
Length = 396
Score = 54.0 bits (124), Expect = 3e-06
Identities = 45/150 (30%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Query: 332 GNARVMMASTPVNTELIGR-VIDVACGRHHTLILTENGL-YSAGDNTFGQLXXXXXXXXX 389
G + +S + L+G+ VI VA G H+ +T+NG+ Y G+N+ GQ
Sbjct: 73 GPVEICPSSPILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVP 132
Query: 390 XXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQ 449
LA ++ +A G H+ A+ + W WG QLGL
Sbjct: 133 EPNPVSIADSEASPLLA--VRILQLACGEEHTLALSISREI--WAWGTGCQLGLITTAFP 188
Query: 450 WT-PQLVTKFLGRKVQSVGCGACHSVLLTR 478
T PQ V GR V V CGA HS+ L +
Sbjct: 189 VTKPQKVEHLAGRVVLQVACGAFHSLALVQ 218
Score = 46.8 bits (106), Expect = 4e-04
Identities = 38/156 (24%), Positives = 67/156 (42%), Gaps = 12/156 (7%)
Query: 451 TPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALH 510
TP+ + + G+ V G H VLLT GE+++ G ++ + + +
Sbjct: 31 TPERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLLWRSGPVEICPSSPILENALVG 90
Query: 511 EPVRALAAGYFHNLALTHKGEVYVWGA-SPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLA 569
+ V +A G FH+ A+T G Y+WG S Q EP+ ++ D +
Sbjct: 91 QYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIA-----DSEAS 145
Query: 570 PSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWG 605
P + RI+Q++ G H+ ++ I+ WG
Sbjct: 146 PL------LAVRILQLACGEEHTLALSISREIWAWG 175
Score = 45.6 bits (103), Expect = 9e-04
Identities = 36/129 (27%), Positives = 53/129 (41%), Gaps = 12/129 (9%)
Query: 408 GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQ---------LVTKF 458
G ++ VA G +HS AV G WG GQ + N Q+ P+ +
Sbjct: 90 GQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVAN--QQYVPEPNPVSIADSEASPL 147
Query: 459 LGRKVQSVGCGACHSVLLTRGGELWACGASV-FGQLGTGQRGKASLPVRVALHEPVRALA 517
L ++ + CG H++ L+ E+WA G G + T V V +A
Sbjct: 148 LAVRILQLACGEEHTLALSISREIWAWGTGCQLGLITTAFPVTKPQKVEHLAGRVVLQVA 207
Query: 518 AGYFHNLAL 526
G FH+LAL
Sbjct: 208 CGAFHSLAL 216
Score = 36.7 bits (81), Expect = 0.41
Identities = 37/143 (25%), Positives = 61/143 (42%), Gaps = 11/143 (7%)
Query: 407 GGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSV 466
GG ++ A G H + G + ++G + + G I +P L +G+ V +V
Sbjct: 39 GGKTVLQAALGVKHGVLLTEDGEVYSFGT-LLWRSGPVEICPS-SPILENALVGQYVITV 96
Query: 467 GCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHE----PVRA-----LA 517
G+ HS +T G + G + GQ + P V++ + P+ A LA
Sbjct: 97 ATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLA 156
Query: 518 AGYFHNLALTHKGEVYVWGASPQ 540
G H LAL+ E++ WG Q
Sbjct: 157 CGEEHTLALSISREIWAWGTGCQ 179
Score = 32.7 bits (71), Expect = 6.7
Identities = 31/119 (26%), Positives = 46/119 (38%), Gaps = 20/119 (16%)
Query: 517 AAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTT 576
A G H + LT GEVY +G + PSSP L +
Sbjct: 47 ALGVKHGVLLTEDGEVYSFGT----LLWRSGPVEICPSSPIL---------------ENA 87
Query: 577 NVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIR-TETQP 634
V ++ ++ G HS + + G Y WG N GQ +++ + P V I +E P
Sbjct: 88 LVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASP 146
>AF391100-1|AAL14103.1| 1657|Homo sapiens alsin protein.
Length = 1657
Score = 54.0 bits (124), Expect = 3e-06
Identities = 45/150 (30%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Query: 332 GNARVMMASTPVNTELIGR-VIDVACGRHHTLILTENGL-YSAGDNTFGQLXXXXXXXXX 389
G + +S + L+G+ VI VA G H+ +T+NG+ Y G+N+ GQ
Sbjct: 73 GPVEICPSSPILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVP 132
Query: 390 XXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQ 449
LA ++ +A G H+ A+ + W WG QLGL
Sbjct: 133 EPNPVSIADSEASPLLA--VRILQLACGEEHTLALSISREI--WAWGTGCQLGLITTAFP 188
Query: 450 WT-PQLVTKFLGRKVQSVGCGACHSVLLTR 478
T PQ V GR V V CGA HS+ L +
Sbjct: 189 VTKPQKVEHLAGRVVLQVACGAFHSLALVQ 218
Score = 50.8 bits (116), Expect = 2e-05
Identities = 31/97 (31%), Positives = 53/97 (54%), Gaps = 3/97 (3%)
Query: 432 TWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFG 491
TWG G GQLG G++ + P V G++V + G HS+ LT ++++ G++ FG
Sbjct: 530 TWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFG 589
Query: 492 QLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLAL 526
QLG ++P +++ V ++AAG ++L L
Sbjct: 590 QLGHSD-FPTTVPRLAKISSENGVWSIAAGRDYSLFL 625
Score = 46.8 bits (106), Expect = 4e-04
Identities = 38/156 (24%), Positives = 67/156 (42%), Gaps = 12/156 (7%)
Query: 451 TPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALH 510
TP+ + + G+ V G H VLLT GE+++ G ++ + + +
Sbjct: 31 TPERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLLWRSGPVEICPSSPILENALVG 90
Query: 511 EPVRALAAGYFHNLALTHKGEVYVWGA-SPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLA 569
+ V +A G FH+ A+T G Y+WG S Q EP+ ++ D +
Sbjct: 91 QYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIA-----DSEAS 145
Query: 570 PSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWG 605
P + RI+Q++ G H+ ++ I+ WG
Sbjct: 146 PL------LAVRILQLACGEEHTLALSISREIWAWG 175
Score = 45.6 bits (103), Expect = 9e-04
Identities = 36/129 (27%), Positives = 53/129 (41%), Gaps = 12/129 (9%)
Query: 408 GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQ---------LVTKF 458
G ++ VA G +HS AV G WG GQ + N Q+ P+ +
Sbjct: 90 GQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVAN--QQYVPEPNPVSIADSEASPL 147
Query: 459 LGRKVQSVGCGACHSVLLTRGGELWACGASV-FGQLGTGQRGKASLPVRVALHEPVRALA 517
L ++ + CG H++ L+ E+WA G G + T V V +A
Sbjct: 148 LAVRILQLACGEEHTLALSISREIWAWGTGCQLGLITTAFPVTKPQKVEHLAGRVVLQVA 207
Query: 518 AGYFHNLAL 526
G FH+LAL
Sbjct: 208 CGAFHSLAL 216
Score = 43.2 bits (97), Expect = 0.005
Identities = 34/106 (32%), Positives = 52/106 (49%), Gaps = 7/106 (6%)
Query: 440 QLGLGNIDDQWTPQLVTKFLGRKVQSVGC-----GACHSVLLTRGGELWACGASVFGQLG 494
+L L + Q +P+L+ K K ++V G ++L + E+W G GQLG
Sbjct: 481 RLSLPGLLSQVSPRLLRKAARVKTRTVVLTPTYSGEADALLPSLRTEVWTWGKGKEGQLG 540
Query: 495 TGQRGKASLPVRVALHE--PVRALAAGYFHNLALTHKGEVYVWGAS 538
G P+ V + V L AG +H+LALT K +VY WG++
Sbjct: 541 HGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSN 586
Score = 41.1 bits (92), Expect = 0.019
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 2/71 (2%)
Query: 561 HDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQI 620
H D L P CV + + ++ + AG +HS + +Y+WG N GQLG D
Sbjct: 541 HGDVLPRLQPLCVKCLDGK-EVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSD-FPT 598
Query: 621 QIPTEVKIRTE 631
+P KI +E
Sbjct: 599 TVPRLAKISSE 609
Score = 37.5 bits (83), Expect = 0.23
Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Query: 401 LRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLG 460
L V+ G ++ + AG YHS A+ A ++ +WG GQLG + P+L
Sbjct: 551 LCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTT-VPRLAKISSE 609
Query: 461 RKVQSVGCGACHSVLL 476
V S+ G +S+ L
Sbjct: 610 NGVWSIAAGRDYSLFL 625
Score = 36.7 bits (81), Expect = 0.41
Identities = 37/143 (25%), Positives = 61/143 (42%), Gaps = 11/143 (7%)
Query: 407 GGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSV 466
GG ++ A G H + G + ++G + + G I +P L +G+ V +V
Sbjct: 39 GGKTVLQAALGVKHGVLLTEDGEVYSFGT-LLWRSGPVEICPS-SPILENALVGQYVITV 96
Query: 467 GCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHE----PVRA-----LA 517
G+ HS +T G + G + GQ + P V++ + P+ A LA
Sbjct: 97 ATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLA 156
Query: 518 AGYFHNLALTHKGEVYVWGASPQ 540
G H LAL+ E++ WG Q
Sbjct: 157 CGEEHTLALSISREIWAWGTGCQ 179
Score = 32.7 bits (71), Expect = 6.7
Identities = 31/119 (26%), Positives = 46/119 (38%), Gaps = 20/119 (16%)
Query: 517 AAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTT 576
A G H + LT GEVY +G + PSSP L +
Sbjct: 47 ALGVKHGVLLTEDGEVYSFGT----LLWRSGPVEICPSSPIL---------------ENA 87
Query: 577 NVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIR-TETQP 634
V ++ ++ G HS + + G Y WG N GQ +++ + P V I +E P
Sbjct: 88 LVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASP 146
Score = 32.3 bits (70), Expect = 8.8
Identities = 16/31 (51%), Positives = 22/31 (70%), Gaps = 1/31 (3%)
Query: 351 VIDVACGRHHTLILT-ENGLYSAGDNTFGQL 380
VI + G +H+L LT ++ +YS G NTFGQL
Sbjct: 561 VIHLEAGGYHSLALTAKSQVYSWGSNTFGQL 591
>AC007279-1|AAY15058.1| 1598|Homo sapiens unknown protein.
Length = 1598
Score = 54.0 bits (124), Expect = 3e-06
Identities = 45/150 (30%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Query: 332 GNARVMMASTPVNTELIGR-VIDVACGRHHTLILTENGL-YSAGDNTFGQLXXXXXXXXX 389
G + +S + L+G+ VI VA G H+ +T+NG+ Y G+N+ GQ
Sbjct: 14 GPVEICPSSPILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVP 73
Query: 390 XXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQ 449
LA ++ +A G H+ A+ + W WG QLGL
Sbjct: 74 EPNPVSIADSEASPLLA--VRILQLACGEEHTLALSISREI--WAWGTGCQLGLITTAFP 129
Query: 450 WT-PQLVTKFLGRKVQSVGCGACHSVLLTR 478
T PQ V GR V V CGA HS+ L +
Sbjct: 130 VTKPQKVEHLAGRVVLQVACGAFHSLALVQ 159
Score = 50.8 bits (116), Expect = 2e-05
Identities = 31/97 (31%), Positives = 53/97 (54%), Gaps = 3/97 (3%)
Query: 432 TWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFG 491
TWG G GQLG G++ + P V G++V + G HS+ LT ++++ G++ FG
Sbjct: 471 TWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFG 530
Query: 492 QLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLAL 526
QLG ++P +++ V ++AAG ++L L
Sbjct: 531 QLGHSD-FPTTVPRLAKISSENGVWSIAAGRDYSLFL 566
Score = 45.6 bits (103), Expect = 9e-04
Identities = 36/129 (27%), Positives = 53/129 (41%), Gaps = 12/129 (9%)
Query: 408 GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQ---------LVTKF 458
G ++ VA G +HS AV G WG GQ + N Q+ P+ +
Sbjct: 31 GQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVAN--QQYVPEPNPVSIADSEASPL 88
Query: 459 LGRKVQSVGCGACHSVLLTRGGELWACGASV-FGQLGTGQRGKASLPVRVALHEPVRALA 517
L ++ + CG H++ L+ E+WA G G + T V V +A
Sbjct: 89 LAVRILQLACGEEHTLALSISREIWAWGTGCQLGLITTAFPVTKPQKVEHLAGRVVLQVA 148
Query: 518 AGYFHNLAL 526
G FH+LAL
Sbjct: 149 CGAFHSLAL 157
Score = 43.2 bits (97), Expect = 0.005
Identities = 34/106 (32%), Positives = 52/106 (49%), Gaps = 7/106 (6%)
Query: 440 QLGLGNIDDQWTPQLVTKFLGRKVQSVGC-----GACHSVLLTRGGELWACGASVFGQLG 494
+L L + Q +P+L+ K K ++V G ++L + E+W G GQLG
Sbjct: 422 RLSLPGLLSQVSPRLLRKAARVKTRTVVLTPTYSGEADALLPSLRTEVWTWGKGKEGQLG 481
Query: 495 TGQRGKASLPVRVALHE--PVRALAAGYFHNLALTHKGEVYVWGAS 538
G P+ V + V L AG +H+LALT K +VY WG++
Sbjct: 482 HGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSN 527
Score = 41.1 bits (92), Expect = 0.019
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 2/71 (2%)
Query: 561 HDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQI 620
H D L P CV + + ++ + AG +HS + +Y+WG N GQLG D
Sbjct: 482 HGDVLPRLQPLCVKCLDGK-EVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSD-FPT 539
Query: 621 QIPTEVKIRTE 631
+P KI +E
Sbjct: 540 TVPRLAKISSE 550
Score = 37.5 bits (83), Expect = 0.23
Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Query: 401 LRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLG 460
L V+ G ++ + AG YHS A+ A ++ +WG GQLG + P+L
Sbjct: 492 LCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTT-VPRLAKISSE 550
Query: 461 RKVQSVGCGACHSVLL 476
V S+ G +S+ L
Sbjct: 551 NGVWSIAAGRDYSLFL 566
Score = 35.5 bits (78), Expect = 0.95
Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 9/99 (9%)
Query: 451 TPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALH 510
+P L +G+ V +V G+ HS +T G + G + GQ + P V++
Sbjct: 22 SPILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIA 81
Query: 511 E----PVRA-----LAAGYFHNLALTHKGEVYVWGASPQ 540
+ P+ A LA G H LAL+ E++ WG Q
Sbjct: 82 DSEASPLLAVRILQLACGEEHTLALSISREIWAWGTGCQ 120
Score = 32.3 bits (70), Expect = 8.8
Identities = 15/54 (27%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 582 IVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIR-TETQP 634
++ ++ G HS + + G Y WG N GQ +++ + P V I +E P
Sbjct: 34 VITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASP 87
Score = 32.3 bits (70), Expect = 8.8
Identities = 16/31 (51%), Positives = 22/31 (70%), Gaps = 1/31 (3%)
Query: 351 VIDVACGRHHTLILT-ENGLYSAGDNTFGQL 380
VI + G +H+L LT ++ +YS G NTFGQL
Sbjct: 502 VIHLEAGGYHSLALTAKSQVYSWGSNTFGQL 532
>AB053306-1|BAB69015.1| 396|Homo sapiens ALS2 protein.
Length = 396
Score = 54.0 bits (124), Expect = 3e-06
Identities = 45/150 (30%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Query: 332 GNARVMMASTPVNTELIGR-VIDVACGRHHTLILTENGL-YSAGDNTFGQLXXXXXXXXX 389
G + +S + L+G+ VI VA G H+ +T+NG+ Y G+N+ GQ
Sbjct: 73 GPVEICPSSPILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVP 132
Query: 390 XXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQ 449
LA ++ +A G H+ A+ + W WG QLGL
Sbjct: 133 EPNPVSIADSEASPLLA--VRILQLACGEEHTLALSISREI--WAWGTGCQLGLITTAFP 188
Query: 450 WT-PQLVTKFLGRKVQSVGCGACHSVLLTR 478
T PQ V GR V V CGA HS+ L +
Sbjct: 189 VTKPQKVEHLAGRVVLQVACGAFHSLALVQ 218
Score = 45.6 bits (103), Expect = 9e-04
Identities = 38/156 (24%), Positives = 66/156 (42%), Gaps = 12/156 (7%)
Query: 451 TPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALH 510
TP+ + + G+ V G H VLLT GE+++ G + + + +
Sbjct: 31 TPERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEICPSSPILENALVG 90
Query: 511 EPVRALAAGYFHNLALTHKGEVYVWGA-SPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLA 569
+ V +A G FH+ A+T G Y+WG S Q EP+ ++ D +
Sbjct: 91 QYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIA-----DSEAS 145
Query: 570 PSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWG 605
P + RI+Q++ G H+ ++ I+ WG
Sbjct: 146 PL------LAVRILQLACGEEHTLALSISREIWAWG 175
Score = 45.6 bits (103), Expect = 9e-04
Identities = 36/129 (27%), Positives = 53/129 (41%), Gaps = 12/129 (9%)
Query: 408 GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQ---------LVTKF 458
G ++ VA G +HS AV G WG GQ + N Q+ P+ +
Sbjct: 90 GQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVAN--QQYVPEPNPVSIADSEASPL 147
Query: 459 LGRKVQSVGCGACHSVLLTRGGELWACGASV-FGQLGTGQRGKASLPVRVALHEPVRALA 517
L ++ + CG H++ L+ E+WA G G + T V V +A
Sbjct: 148 LAVRILQLACGEEHTLALSISREIWAWGTGCQLGLITTAFPVTKPQKVEHLAGRVVLQVA 207
Query: 518 AGYFHNLAL 526
G FH+LAL
Sbjct: 208 CGAFHSLAL 216
Score = 37.1 bits (82), Expect = 0.31
Identities = 37/143 (25%), Positives = 61/143 (42%), Gaps = 11/143 (7%)
Query: 407 GGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSV 466
GG ++ A G H + G + ++G + + G I +P L +G+ V +V
Sbjct: 39 GGKTVLQAALGVKHGVLLTEDGEVYSFGT-LPWRSGPVEICPS-SPILENALVGQYVITV 96
Query: 467 GCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHE----PVRA-----LA 517
G+ HS +T G + G + GQ + P V++ + P+ A LA
Sbjct: 97 ATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLA 156
Query: 518 AGYFHNLALTHKGEVYVWGASPQ 540
G H LAL+ E++ WG Q
Sbjct: 157 CGEEHTLALSISREIWAWGTGCQ 179
Score = 35.5 bits (78), Expect = 0.95
Identities = 32/119 (26%), Positives = 47/119 (39%), Gaps = 20/119 (16%)
Query: 517 AAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTT 576
A G H + LT GEVY +G P + PSSP L +
Sbjct: 47 ALGVKHGVLLTEDGEVYSFGTLPWRSGPVEIC----PSSPIL---------------ENA 87
Query: 577 NVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIR-TETQP 634
V ++ ++ G HS + + G Y WG N GQ +++ + P V I +E P
Sbjct: 88 LVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASP 146
>AB053305-1|BAB69014.1| 1657|Homo sapiens ALS2 protein.
Length = 1657
Score = 54.0 bits (124), Expect = 3e-06
Identities = 45/150 (30%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Query: 332 GNARVMMASTPVNTELIGR-VIDVACGRHHTLILTENGL-YSAGDNTFGQLXXXXXXXXX 389
G + +S + L+G+ VI VA G H+ +T+NG+ Y G+N+ GQ
Sbjct: 73 GPVEICPSSPILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVP 132
Query: 390 XXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQ 449
LA ++ +A G H+ A+ + W WG QLGL
Sbjct: 133 EPNPVSIADSEASPLLA--VRILQLACGEEHTLALSISREI--WAWGTGCQLGLITTAFP 188
Query: 450 WT-PQLVTKFLGRKVQSVGCGACHSVLLTR 478
T PQ V GR V V CGA HS+ L +
Sbjct: 189 VTKPQKVEHLAGRVVLQVACGAFHSLALVQ 218
Score = 50.8 bits (116), Expect = 2e-05
Identities = 31/97 (31%), Positives = 53/97 (54%), Gaps = 3/97 (3%)
Query: 432 TWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFG 491
TWG G GQLG G++ + P V G++V + G HS+ LT ++++ G++ FG
Sbjct: 530 TWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFG 589
Query: 492 QLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLAL 526
QLG ++P +++ V ++AAG ++L L
Sbjct: 590 QLGHSD-FPTTVPRLAKISSENGVWSIAAGRDYSLFL 625
Score = 45.6 bits (103), Expect = 9e-04
Identities = 38/156 (24%), Positives = 66/156 (42%), Gaps = 12/156 (7%)
Query: 451 TPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALH 510
TP+ + + G+ V G H VLLT GE+++ G + + + +
Sbjct: 31 TPERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEICPSSPILENALVG 90
Query: 511 EPVRALAAGYFHNLALTHKGEVYVWGA-SPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLA 569
+ V +A G FH+ A+T G Y+WG S Q EP+ ++ D +
Sbjct: 91 QYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIA-----DSEAS 145
Query: 570 PSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWG 605
P + RI+Q++ G H+ ++ I+ WG
Sbjct: 146 PL------LAVRILQLACGEEHTLALSISREIWAWG 175
Score = 45.6 bits (103), Expect = 9e-04
Identities = 36/129 (27%), Positives = 53/129 (41%), Gaps = 12/129 (9%)
Query: 408 GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQ---------LVTKF 458
G ++ VA G +HS AV G WG GQ + N Q+ P+ +
Sbjct: 90 GQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVAN--QQYVPEPNPVSIADSEASPL 147
Query: 459 LGRKVQSVGCGACHSVLLTRGGELWACGASV-FGQLGTGQRGKASLPVRVALHEPVRALA 517
L ++ + CG H++ L+ E+WA G G + T V V +A
Sbjct: 148 LAVRILQLACGEEHTLALSISREIWAWGTGCQLGLITTAFPVTKPQKVEHLAGRVVLQVA 207
Query: 518 AGYFHNLAL 526
G FH+LAL
Sbjct: 208 CGAFHSLAL 216
Score = 43.2 bits (97), Expect = 0.005
Identities = 34/106 (32%), Positives = 52/106 (49%), Gaps = 7/106 (6%)
Query: 440 QLGLGNIDDQWTPQLVTKFLGRKVQSVGC-----GACHSVLLTRGGELWACGASVFGQLG 494
+L L + Q +P+L+ K K ++V G ++L + E+W G GQLG
Sbjct: 481 RLSLPGLLSQVSPRLLRKAARVKTRTVVLTPTYSGEADALLPSLRTEVWTWGKGKEGQLG 540
Query: 495 TGQRGKASLPVRVALHE--PVRALAAGYFHNLALTHKGEVYVWGAS 538
G P+ V + V L AG +H+LALT K +VY WG++
Sbjct: 541 HGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSN 586
Score = 41.1 bits (92), Expect = 0.019
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 2/71 (2%)
Query: 561 HDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQI 620
H D L P CV + + ++ + AG +HS + +Y+WG N GQLG D
Sbjct: 541 HGDVLPRLQPLCVKCLDGK-EVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSD-FPT 598
Query: 621 QIPTEVKIRTE 631
+P KI +E
Sbjct: 599 TVPRLAKISSE 609
Score = 37.5 bits (83), Expect = 0.23
Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Query: 401 LRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLG 460
L V+ G ++ + AG YHS A+ A ++ +WG GQLG + P+L
Sbjct: 551 LCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTT-VPRLAKISSE 609
Query: 461 RKVQSVGCGACHSVLL 476
V S+ G +S+ L
Sbjct: 610 NGVWSIAAGRDYSLFL 625
Score = 37.1 bits (82), Expect = 0.31
Identities = 37/143 (25%), Positives = 61/143 (42%), Gaps = 11/143 (7%)
Query: 407 GGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSV 466
GG ++ A G H + G + ++G + + G I +P L +G+ V +V
Sbjct: 39 GGKTVLQAALGVKHGVLLTEDGEVYSFGT-LPWRSGPVEICPS-SPILENALVGQYVITV 96
Query: 467 GCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHE----PVRA-----LA 517
G+ HS +T G + G + GQ + P V++ + P+ A LA
Sbjct: 97 ATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLA 156
Query: 518 AGYFHNLALTHKGEVYVWGASPQ 540
G H LAL+ E++ WG Q
Sbjct: 157 CGEEHTLALSISREIWAWGTGCQ 179
Score = 35.5 bits (78), Expect = 0.95
Identities = 32/119 (26%), Positives = 47/119 (39%), Gaps = 20/119 (16%)
Query: 517 AAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTT 576
A G H + LT GEVY +G P + PSSP L +
Sbjct: 47 ALGVKHGVLLTEDGEVYSFGTLPWRSGPVEIC----PSSPIL---------------ENA 87
Query: 577 NVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIR-TETQP 634
V ++ ++ G HS + + G Y WG N GQ +++ + P V I +E P
Sbjct: 88 LVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASP 146
Score = 32.3 bits (70), Expect = 8.8
Identities = 16/31 (51%), Positives = 22/31 (70%), Gaps = 1/31 (3%)
Query: 351 VIDVACGRHHTLILT-ENGLYSAGDNTFGQL 380
VI + G +H+L LT ++ +YS G NTFGQL
Sbjct: 561 VIHLEAGGYHSLALTAKSQVYSWGSNTFGQL 591
>AB046783-1|BAB13389.2| 1658|Homo sapiens KIAA1563 protein protein.
Length = 1658
Score = 54.0 bits (124), Expect = 3e-06
Identities = 45/150 (30%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Query: 332 GNARVMMASTPVNTELIGR-VIDVACGRHHTLILTENGL-YSAGDNTFGQLXXXXXXXXX 389
G + +S + L+G+ VI VA G H+ +T+NG+ Y G+N+ GQ
Sbjct: 74 GPVEICPSSPILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVP 133
Query: 390 XXXXXXXXXXVLRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQ 449
LA ++ +A G H+ A+ + W WG QLGL
Sbjct: 134 EPNPVSIADSEASPLLA--VRILQLACGEEHTLALSISREI--WAWGTGCQLGLITTAFP 189
Query: 450 WT-PQLVTKFLGRKVQSVGCGACHSVLLTR 478
T PQ V GR V V CGA HS+ L +
Sbjct: 190 VTKPQKVEHLAGRVVLQVACGAFHSLALVQ 219
Score = 50.8 bits (116), Expect = 2e-05
Identities = 31/97 (31%), Positives = 53/97 (54%), Gaps = 3/97 (3%)
Query: 432 TWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFG 491
TWG G GQLG G++ + P V G++V + G HS+ LT ++++ G++ FG
Sbjct: 531 TWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFG 590
Query: 492 QLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLAL 526
QLG ++P +++ V ++AAG ++L L
Sbjct: 591 QLGHSD-FPTTVPRLAKISSENGVWSIAAGRDYSLFL 626
Score = 45.6 bits (103), Expect = 9e-04
Identities = 38/156 (24%), Positives = 66/156 (42%), Gaps = 12/156 (7%)
Query: 451 TPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALH 510
TP+ + + G+ V G H VLLT GE+++ G + + + +
Sbjct: 32 TPERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEICPSSPILENALVG 91
Query: 511 EPVRALAAGYFHNLALTHKGEVYVWGA-SPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLA 569
+ V +A G FH+ A+T G Y+WG S Q EP+ ++ D +
Sbjct: 92 QYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIA-----DSEAS 146
Query: 570 PSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWG 605
P + RI+Q++ G H+ ++ I+ WG
Sbjct: 147 PL------LAVRILQLACGEEHTLALSISREIWAWG 176
Score = 45.6 bits (103), Expect = 9e-04
Identities = 36/129 (27%), Positives = 53/129 (41%), Gaps = 12/129 (9%)
Query: 408 GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQ---------LVTKF 458
G ++ VA G +HS AV G WG GQ + N Q+ P+ +
Sbjct: 91 GQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVAN--QQYVPEPNPVSIADSEASPL 148
Query: 459 LGRKVQSVGCGACHSVLLTRGGELWACGASV-FGQLGTGQRGKASLPVRVALHEPVRALA 517
L ++ + CG H++ L+ E+WA G G + T V V +A
Sbjct: 149 LAVRILQLACGEEHTLALSISREIWAWGTGCQLGLITTAFPVTKPQKVEHLAGRVVLQVA 208
Query: 518 AGYFHNLAL 526
G FH+LAL
Sbjct: 209 CGAFHSLAL 217
Score = 43.2 bits (97), Expect = 0.005
Identities = 34/106 (32%), Positives = 52/106 (49%), Gaps = 7/106 (6%)
Query: 440 QLGLGNIDDQWTPQLVTKFLGRKVQSVGC-----GACHSVLLTRGGELWACGASVFGQLG 494
+L L + Q +P+L+ K K ++V G ++L + E+W G GQLG
Sbjct: 482 RLSLPGLLSQVSPRLLRKAARVKTRTVVLTPTYSGEADALLPSLRTEVWTWGKGKEGQLG 541
Query: 495 TGQRGKASLPVRVALHE--PVRALAAGYFHNLALTHKGEVYVWGAS 538
G P+ V + V L AG +H+LALT K +VY WG++
Sbjct: 542 HGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSN 587
Score = 41.1 bits (92), Expect = 0.019
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 2/71 (2%)
Query: 561 HDDNDRYLAPSCVDTTNVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQI 620
H D L P CV + + ++ + AG +HS + +Y+WG N GQLG D
Sbjct: 542 HGDVLPRLQPLCVKCLDGK-EVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSD-FPT 599
Query: 621 QIPTEVKIRTE 631
+P KI +E
Sbjct: 600 TVPRLAKISSE 610
Score = 37.5 bits (83), Expect = 0.23
Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Query: 401 LRVRLAGGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLG 460
L V+ G ++ + AG YHS A+ A ++ +WG GQLG + P+L
Sbjct: 552 LCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTT-VPRLAKISSE 610
Query: 461 RKVQSVGCGACHSVLL 476
V S+ G +S+ L
Sbjct: 611 NGVWSIAAGRDYSLFL 626
Score = 37.1 bits (82), Expect = 0.31
Identities = 37/143 (25%), Positives = 61/143 (42%), Gaps = 11/143 (7%)
Query: 407 GGAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSV 466
GG ++ A G H + G + ++G + + G I +P L +G+ V +V
Sbjct: 40 GGKTVLQAALGVKHGVLLTEDGEVYSFGT-LPWRSGPVEICPS-SPILENALVGQYVITV 97
Query: 467 GCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRVALHE----PVRA-----LA 517
G+ HS +T G + G + GQ + P V++ + P+ A LA
Sbjct: 98 ATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLA 157
Query: 518 AGYFHNLALTHKGEVYVWGASPQ 540
G H LAL+ E++ WG Q
Sbjct: 158 CGEEHTLALSISREIWAWGTGCQ 180
Score = 35.5 bits (78), Expect = 0.95
Identities = 32/119 (26%), Positives = 47/119 (39%), Gaps = 20/119 (16%)
Query: 517 AAGYFHNLALTHKGEVYVWGASPQQVXXXXXXXXXEPSSPTLPFHDDNDRYLAPSCVDTT 576
A G H + LT GEVY +G P + PSSP L +
Sbjct: 48 ALGVKHGVLLTEDGEVYSFGTLPWRSGPVEIC----PSSPIL---------------ENA 88
Query: 577 NVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIR-TETQP 634
V ++ ++ G HS + + G Y WG N GQ +++ + P V I +E P
Sbjct: 89 LVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASP 147
Score = 32.3 bits (70), Expect = 8.8
Identities = 16/31 (51%), Positives = 22/31 (70%), Gaps = 1/31 (3%)
Query: 351 VIDVACGRHHTLILT-ENGLYSAGDNTFGQL 380
VI + G +H+L LT ++ +YS G NTFGQL
Sbjct: 562 VIHLEAGGYHSLALTAKSQVYSWGSNTFGQL 592
>DQ005634-1|AAY55907.1| 1196|Homo sapiens inhibitor of Bruton's
tyrosine kinase-beta protein.
Length = 1196
Score = 53.2 bits (122), Expect = 4e-06
Identities = 55/187 (29%), Positives = 84/187 (44%), Gaps = 22/187 (11%)
Query: 432 TWGWGVHGQLGLGNIDDQWTPQLVTKF--LGRKVQSVGCGACHSVLLTRGGELWACGASV 489
TWG + LG G+ + + P+LV F G ++ V HSV L++ G+++ CG
Sbjct: 146 TWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGP 205
Query: 490 FGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXX 547
G+LG G +P V +AA H + LT G VY +G +
Sbjct: 206 GGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLN----IFHQL 261
Query: 548 XXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGR-IVQISAGWHHSCIINNMGSIYTWGL 606
PSS +P +YL +GR I+ ++AG H+ ++ ++YT GL
Sbjct: 262 GIIPPPSSCNVP-RQIQAKYL----------KGRTIIGVAAGRFHT-VLWTREAVYTMGL 309
Query: 607 NFDGQLG 613
N GQLG
Sbjct: 310 N-GGQLG 315
Score = 51.2 bits (117), Expect = 2e-05
Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 6/129 (4%)
Query: 419 YHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTR 478
+HS + G++ T G G G+LG G+ P+LV G V H+V+LT
Sbjct: 187 FHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTE 246
Query: 479 GGELWACGASVFGQLG-TGQRGKASLPVRVALH----EPVRALAAGYFHNLALTHKGEVY 533
G ++ G ++F QLG ++P ++ + +AAG FH + T + VY
Sbjct: 247 DGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREA-VY 305
Query: 534 VWGASPQQV 542
G + Q+
Sbjct: 306 TMGLNGGQL 314
Score = 33.1 bits (72), Expect = 5.0
Identities = 40/132 (30%), Positives = 62/132 (46%), Gaps = 13/132 (9%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWT--PQLVTKFL-GRKVQSVGCGA 470
VAA H+ + G + T+G + QLG+ Q+ K+L GR + V G
Sbjct: 234 VAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGR 293
Query: 471 CHSVLLTRGGELWACGASVFGQLG--TGQRGK--ASLPVRV-ALHEPVRAL---AAGYFH 522
H+VL TR ++ G + GQLG G+ + P +V ALH AL AA
Sbjct: 294 FHTVLWTREA-VYTMGLN-GGQLGCLLDPNGEKCVTAPRQVSALHHKDIALSLVAASDGA 351
Query: 523 NLALTHKGEVYV 534
+ +T +G++Y+
Sbjct: 352 TVCVTTRGDIYL 363
Score = 32.3 bits (70), Expect = 8.8
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 557 TLPFHDDNDRYLAPSCVDTTNVRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSG 615
TL N ++ P VD + G I Q+ HS ++ G +YT G G+LG G
Sbjct: 154 TLGHGSQNSKH-HPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHG 212
Query: 616 DRKQIQIPTEVK 627
D + +P V+
Sbjct: 213 DEQTCLVPRLVE 224
>DQ005633-1|AAY55906.1| 1353|Homo sapiens inhibitor of Bruton's
tyrosine kinase-alpha protein.
Length = 1353
Score = 53.2 bits (122), Expect = 4e-06
Identities = 55/187 (29%), Positives = 84/187 (44%), Gaps = 22/187 (11%)
Query: 432 TWGWGVHGQLGLGNIDDQWTPQLVTKF--LGRKVQSVGCGACHSVLLTRGGELWACGASV 489
TWG + LG G+ + + P+LV F G ++ V HSV L++ G+++ CG
Sbjct: 146 TWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGP 205
Query: 490 FGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXX 547
G+LG G +P V +AA H + LT G VY +G +
Sbjct: 206 GGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLN----IFHQL 261
Query: 548 XXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGR-IVQISAGWHHSCIINNMGSIYTWGL 606
PSS +P +YL +GR I+ ++AG H+ ++ ++YT GL
Sbjct: 262 GIIPPPSSCNVP-RQIQAKYL----------KGRTIIGVAAGRFHT-VLWTREAVYTMGL 309
Query: 607 NFDGQLG 613
N GQLG
Sbjct: 310 N-GGQLG 315
Score = 51.2 bits (117), Expect = 2e-05
Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 6/129 (4%)
Query: 419 YHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTR 478
+HS + G++ T G G G+LG G+ P+LV G V H+V+LT
Sbjct: 187 FHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTE 246
Query: 479 GGELWACGASVFGQLG-TGQRGKASLPVRVALH----EPVRALAAGYFHNLALTHKGEVY 533
G ++ G ++F QLG ++P ++ + +AAG FH + T + VY
Sbjct: 247 DGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREA-VY 305
Query: 534 VWGASPQQV 542
G + Q+
Sbjct: 306 TMGLNGGQL 314
Score = 33.1 bits (72), Expect = 5.0
Identities = 40/132 (30%), Positives = 62/132 (46%), Gaps = 13/132 (9%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWT--PQLVTKFL-GRKVQSVGCGA 470
VAA H+ + G + T+G + QLG+ Q+ K+L GR + V G
Sbjct: 234 VAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGR 293
Query: 471 CHSVLLTRGGELWACGASVFGQLG--TGQRGK--ASLPVRV-ALHEPVRAL---AAGYFH 522
H+VL TR ++ G + GQLG G+ + P +V ALH AL AA
Sbjct: 294 FHTVLWTREA-VYTMGLN-GGQLGCLLDPNGEKCVTAPRQVSALHHKDIALSLVAASDGA 351
Query: 523 NLALTHKGEVYV 534
+ +T +G++Y+
Sbjct: 352 TVCVTTRGDIYL 363
Score = 32.3 bits (70), Expect = 8.8
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 557 TLPFHDDNDRYLAPSCVDTTNVRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSG 615
TL N ++ P VD + G I Q+ HS ++ G +YT G G+LG G
Sbjct: 154 TLGHGSQNSKH-HPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHG 212
Query: 616 DRKQIQIPTEVK 627
D + +P V+
Sbjct: 213 DEQTCLVPRLVE 224
>BC113698-1|AAI13699.1| 1353|Homo sapiens inhibitor of Bruton
agammaglobulinemia tyrosine kinase protein.
Length = 1353
Score = 53.2 bits (122), Expect = 4e-06
Identities = 55/187 (29%), Positives = 84/187 (44%), Gaps = 22/187 (11%)
Query: 432 TWGWGVHGQLGLGNIDDQWTPQLVTKF--LGRKVQSVGCGACHSVLLTRGGELWACGASV 489
TWG + LG G+ + + P+LV F G ++ V HSV L++ G+++ CG
Sbjct: 146 TWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGP 205
Query: 490 FGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXX 547
G+LG G +P V +AA H + LT G VY +G +
Sbjct: 206 GGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLN----IFHQL 261
Query: 548 XXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGR-IVQISAGWHHSCIINNMGSIYTWGL 606
PSS +P +YL +GR I+ ++AG H+ ++ ++YT GL
Sbjct: 262 GIIPPPSSCNVP-RQIQAKYL----------KGRTIIGVAAGRFHT-VLWTREAVYTMGL 309
Query: 607 NFDGQLG 613
N GQLG
Sbjct: 310 N-GGQLG 315
Score = 51.2 bits (117), Expect = 2e-05
Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 6/129 (4%)
Query: 419 YHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTR 478
+HS + G++ T G G G+LG G+ P+LV G V H+V+LT
Sbjct: 187 FHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTE 246
Query: 479 GGELWACGASVFGQLG-TGQRGKASLPVRVALH----EPVRALAAGYFHNLALTHKGEVY 533
G ++ G ++F QLG ++P ++ + +AAG FH + T + VY
Sbjct: 247 DGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREA-VY 305
Query: 534 VWGASPQQV 542
G + Q+
Sbjct: 306 TMGLNGGQL 314
Score = 33.1 bits (72), Expect = 5.0
Identities = 40/132 (30%), Positives = 62/132 (46%), Gaps = 13/132 (9%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWT--PQLVTKFL-GRKVQSVGCGA 470
VAA H+ + G + T+G + QLG+ Q+ K+L GR + V G
Sbjct: 234 VAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGR 293
Query: 471 CHSVLLTRGGELWACGASVFGQLG--TGQRGK--ASLPVRV-ALHEPVRAL---AAGYFH 522
H+VL TR ++ G + GQLG G+ + P +V ALH AL AA
Sbjct: 294 FHTVLWTREA-VYTMGLN-GGQLGCLLDPNGEKCVTAPRQVSALHHKDIALSLVAASDGA 351
Query: 523 NLALTHKGEVYV 534
+ +T +G++Y+
Sbjct: 352 TVCVTTRGDIYL 363
Score = 32.3 bits (70), Expect = 8.8
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 557 TLPFHDDNDRYLAPSCVDTTNVRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSG 615
TL N ++ P VD + G I Q+ HS ++ G +YT G G+LG G
Sbjct: 154 TLGHGSQNSKH-HPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHG 212
Query: 616 DRKQIQIPTEVK 627
D + +P V+
Sbjct: 213 DEQTCLVPRLVE 224
>BC113696-1|AAI13697.1| 1353|Homo sapiens inhibitor of Bruton
agammaglobulinemia tyrosine kinase protein.
Length = 1353
Score = 53.2 bits (122), Expect = 4e-06
Identities = 55/187 (29%), Positives = 84/187 (44%), Gaps = 22/187 (11%)
Query: 432 TWGWGVHGQLGLGNIDDQWTPQLVTKF--LGRKVQSVGCGACHSVLLTRGGELWACGASV 489
TWG + LG G+ + + P+LV F G ++ V HSV L++ G+++ CG
Sbjct: 146 TWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGP 205
Query: 490 FGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXX 547
G+LG G +P V +AA H + LT G VY +G +
Sbjct: 206 GGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLN----IFHQL 261
Query: 548 XXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGR-IVQISAGWHHSCIINNMGSIYTWGL 606
PSS +P +YL +GR I+ ++AG H+ ++ ++YT GL
Sbjct: 262 GIIPPPSSCNVP-RQIQAKYL----------KGRTIIGVAAGRFHT-VLWTREAVYTMGL 309
Query: 607 NFDGQLG 613
N GQLG
Sbjct: 310 N-GGQLG 315
Score = 51.2 bits (117), Expect = 2e-05
Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 6/129 (4%)
Query: 419 YHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTR 478
+HS + G++ T G G G+LG G+ P+LV G V H+V+LT
Sbjct: 187 FHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTE 246
Query: 479 GGELWACGASVFGQLG-TGQRGKASLPVRVALH----EPVRALAAGYFHNLALTHKGEVY 533
G ++ G ++F QLG ++P ++ + +AAG FH + T + VY
Sbjct: 247 DGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREA-VY 305
Query: 534 VWGASPQQV 542
G + Q+
Sbjct: 306 TMGLNGGQL 314
Score = 33.1 bits (72), Expect = 5.0
Identities = 40/132 (30%), Positives = 62/132 (46%), Gaps = 13/132 (9%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWT--PQLVTKFL-GRKVQSVGCGA 470
VAA H+ + G + T+G + QLG+ Q+ K+L GR + V G
Sbjct: 234 VAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGR 293
Query: 471 CHSVLLTRGGELWACGASVFGQLG--TGQRGK--ASLPVRV-ALHEPVRAL---AAGYFH 522
H+VL TR ++ G + GQLG G+ + P +V ALH AL AA
Sbjct: 294 FHTVLWTREA-VYTMGLN-GGQLGCLLDPNGEKCVTAPRQVSALHHKDIALSLVAASDGA 351
Query: 523 NLALTHKGEVYV 534
+ +T +G++Y+
Sbjct: 352 TVCVTTRGDIYL 363
Score = 32.3 bits (70), Expect = 8.8
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 557 TLPFHDDNDRYLAPSCVDTTNVRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSG 615
TL N ++ P VD + G I Q+ HS ++ G +YT G G+LG G
Sbjct: 154 TLGHGSQNSKH-HPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHG 212
Query: 616 DRKQIQIPTEVK 627
D + +P V+
Sbjct: 213 DEQTCLVPRLVE 224
>AL050333-2|CAI23416.1| 1187|Homo sapiens RP1-93K22.1 protein.
Length = 1187
Score = 53.2 bits (122), Expect = 4e-06
Identities = 55/187 (29%), Positives = 84/187 (44%), Gaps = 22/187 (11%)
Query: 432 TWGWGVHGQLGLGNIDDQWTPQLVTKF--LGRKVQSVGCGACHSVLLTRGGELWACGASV 489
TWG + LG G+ + + P+LV F G ++ V HSV L++ G+++ CG
Sbjct: 142 TWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGP 201
Query: 490 FGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXX 547
G+LG G +P V +AA H + LT G VY +G +
Sbjct: 202 GGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLN----IFHQL 257
Query: 548 XXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGR-IVQISAGWHHSCIINNMGSIYTWGL 606
PSS +P +YL +GR I+ ++AG H+ ++ ++YT GL
Sbjct: 258 GIIPPPSSCNVP-RQIQAKYL----------KGRTIIGVAAGRFHT-VLWTREAVYTMGL 305
Query: 607 NFDGQLG 613
N GQLG
Sbjct: 306 N-GGQLG 311
Score = 51.2 bits (117), Expect = 2e-05
Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 6/129 (4%)
Query: 419 YHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTR 478
+HS + G++ T G G G+LG G+ P+LV G V H+V+LT
Sbjct: 183 FHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTE 242
Query: 479 GGELWACGASVFGQLG-TGQRGKASLPVRVALH----EPVRALAAGYFHNLALTHKGEVY 533
G ++ G ++F QLG ++P ++ + +AAG FH + T + VY
Sbjct: 243 DGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREA-VY 301
Query: 534 VWGASPQQV 542
G + Q+
Sbjct: 302 TMGLNGGQL 310
Score = 33.1 bits (72), Expect = 5.0
Identities = 40/132 (30%), Positives = 62/132 (46%), Gaps = 13/132 (9%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWT--PQLVTKFL-GRKVQSVGCGA 470
VAA H+ + G + T+G + QLG+ Q+ K+L GR + V G
Sbjct: 230 VAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGR 289
Query: 471 CHSVLLTRGGELWACGASVFGQLG--TGQRGK--ASLPVRV-ALHEPVRAL---AAGYFH 522
H+VL TR ++ G + GQLG G+ + P +V ALH AL AA
Sbjct: 290 FHTVLWTREA-VYTMGLN-GGQLGCLLDPNGEKCVTAPRQVSALHHKDIALSLVAASDGA 347
Query: 523 NLALTHKGEVYV 534
+ +T +G++Y+
Sbjct: 348 TVCVTTRGDIYL 359
Score = 32.3 bits (70), Expect = 8.8
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 557 TLPFHDDNDRYLAPSCVDTTNVRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSG 615
TL N ++ P VD + G I Q+ HS ++ G +YT G G+LG G
Sbjct: 150 TLGHGSQNSKH-HPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHG 208
Query: 616 DRKQIQIPTEVK 627
D + +P V+
Sbjct: 209 DEQTCLVPRLVE 220
>AB037838-1|BAA92655.2| 1379|Homo sapiens KIAA1417 protein protein.
Length = 1379
Score = 53.2 bits (122), Expect = 4e-06
Identities = 55/187 (29%), Positives = 84/187 (44%), Gaps = 22/187 (11%)
Query: 432 TWGWGVHGQLGLGNIDDQWTPQLVTKF--LGRKVQSVGCGACHSVLLTRGGELWACGASV 489
TWG + LG G+ + + P+LV F G ++ V HSV L++ G+++ CG
Sbjct: 172 TWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGP 231
Query: 490 FGQLGTGQRGKASLP--VRVALHEPVRALAAGYFHNLALTHKGEVYVWGASPQQVXXXXX 547
G+LG G +P V +AA H + LT G VY +G +
Sbjct: 232 GGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLN----IFHQL 287
Query: 548 XXXXEPSSPTLPFHDDNDRYLAPSCVDTTNVRGR-IVQISAGWHHSCIINNMGSIYTWGL 606
PSS +P +YL +GR I+ ++AG H+ ++ ++YT GL
Sbjct: 288 GIIPPPSSCNVP-RQIQAKYL----------KGRTIIGVAAGRFHT-VLWTREAVYTMGL 335
Query: 607 NFDGQLG 613
N GQLG
Sbjct: 336 N-GGQLG 341
Score = 51.2 bits (117), Expect = 2e-05
Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 6/129 (4%)
Query: 419 YHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTR 478
+HS + G++ T G G G+LG G+ P+LV G V H+V+LT
Sbjct: 213 FHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTE 272
Query: 479 GGELWACGASVFGQLG-TGQRGKASLPVRVALH----EPVRALAAGYFHNLALTHKGEVY 533
G ++ G ++F QLG ++P ++ + +AAG FH + T + VY
Sbjct: 273 DGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREA-VY 331
Query: 534 VWGASPQQV 542
G + Q+
Sbjct: 332 TMGLNGGQL 340
Score = 33.1 bits (72), Expect = 5.0
Identities = 40/132 (30%), Positives = 62/132 (46%), Gaps = 13/132 (9%)
Query: 414 VAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWT--PQLVTKFL-GRKVQSVGCGA 470
VAA H+ + G + T+G + QLG+ Q+ K+L GR + V G
Sbjct: 260 VAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGR 319
Query: 471 CHSVLLTRGGELWACGASVFGQLG--TGQRGK--ASLPVRV-ALHEPVRAL---AAGYFH 522
H+VL TR ++ G + GQLG G+ + P +V ALH AL AA
Sbjct: 320 FHTVLWTREA-VYTMGLN-GGQLGCLLDPNGEKCVTAPRQVSALHHKDIALSLVAASDGA 377
Query: 523 NLALTHKGEVYV 534
+ +T +G++Y+
Sbjct: 378 TVCVTTRGDIYL 389
Score = 32.3 bits (70), Expect = 8.8
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 557 TLPFHDDNDRYLAPSCVDTTNVRG-RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSG 615
TL N ++ P VD + G I Q+ HS ++ G +YT G G+LG G
Sbjct: 180 TLGHGSQNSKH-HPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHG 238
Query: 616 DRKQIQIPTEVK 627
D + +P V+
Sbjct: 239 DEQTCLVPRLVE 250
>BC067293-1|AAH67293.1| 580|Homo sapiens F-box protein 24 protein.
Length = 580
Score = 50.0 bits (114), Expect = 4e-05
Identities = 37/113 (32%), Positives = 58/113 (51%), Gaps = 7/113 (6%)
Query: 409 APLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGC 468
A ++ A G+ H VD GR+ G +GQLG G+ D+ P V +L R + ++ C
Sbjct: 357 AKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVC-YLQRPI-TLWC 414
Query: 469 GACHSVLLTRGG----ELWACGASVFGQLGTGQRGKASLPVRVALHEPVRALA 517
G HS++L++ EL CG G+L +G AS V++ + P+ A A
Sbjct: 415 GLNHSLVLSQSSEFSKELLGCGCGAGGRLPGWPKGSASF-VKLQVKVPLCACA 466
Score = 40.7 bits (91), Expect = 0.025
Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 3/82 (3%)
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMKSD 640
+I+ + G++H +++ G I+ G N GQLG+GD+ PT+V +P T+
Sbjct: 358 KILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYL--QRPITLWCG 415
Query: 641 SEKTTDADENMEFNTKALVGCG 662
+ ++ EF +K L+GCG
Sbjct: 416 LNHSLVLSQSSEF-SKELLGCG 436
Score = 34.3 bits (75), Expect = 2.2
Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 4/85 (4%)
Query: 448 DQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV 507
DQ P ++ L K+ G H L+ G ++ G + +GQLGTG + P +V
Sbjct: 346 DQQMPLALS--LPAKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQV 403
Query: 508 A-LHEPVRALAAGYFHNLALTHKGE 531
L P+ L G H+L L+ E
Sbjct: 404 CYLQRPI-TLWCGLNHSLVLSQSSE 427
>AC069281-1|AAP21863.1| 580|Homo sapiens unknown protein.
Length = 580
Score = 50.0 bits (114), Expect = 4e-05
Identities = 37/113 (32%), Positives = 58/113 (51%), Gaps = 7/113 (6%)
Query: 409 APLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQSVGC 468
A ++ A G+ H VD GR+ G +GQLG G+ D+ P V +L R + ++ C
Sbjct: 357 AKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVC-YLQRPI-TLWC 414
Query: 469 GACHSVLLTRGG----ELWACGASVFGQLGTGQRGKASLPVRVALHEPVRALA 517
G HS++L++ EL CG G+L +G AS V++ + P+ A A
Sbjct: 415 GLNHSLVLSQSSEFSKELLGCGCGAGGRLPGWPKGSASF-VKLQVKVPLCACA 466
Score = 40.7 bits (91), Expect = 0.025
Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 3/82 (3%)
Query: 581 RIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMKSD 640
+I+ + G++H +++ G I+ G N GQLG+GD+ PT+V +P T+
Sbjct: 358 KILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYL--QRPITLWCG 415
Query: 641 SEKTTDADENMEFNTKALVGCG 662
+ ++ EF +K L+GCG
Sbjct: 416 LNHSLVLSQSSEF-SKELLGCG 436
Score = 34.3 bits (75), Expect = 2.2
Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 4/85 (4%)
Query: 448 DQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV 507
DQ P ++ L K+ G H L+ G ++ G + +GQLGTG + P +V
Sbjct: 346 DQQMPLALS--LPAKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQV 403
Query: 508 A-LHEPVRALAAGYFHNLALTHKGE 531
L P+ L G H+L L+ E
Sbjct: 404 CYLQRPI-TLWCGLNHSLVLSQSSE 427
>AF225404-1|AAO27482.1| 259|Homo sapiens HERC2 protein.
Length = 259
Score = 48.4 bits (110), Expect = 1e-04
Identities = 28/84 (33%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Query: 423 AVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLV--TKFLGRKVQSVGCGACHSVLLTRGG 480
AV A G+L G+G G+LG+G + TP L+ + + K +V G H + L+ G
Sbjct: 174 AVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEG 233
Query: 481 ELWACGASVFGQLGTGQRGKASLP 504
E+++ G + G+LG G R P
Sbjct: 234 EVYSWGEAEDGKLGHGNRSPCDRP 257
Score = 46.4 bits (105), Expect = 5e-04
Identities = 41/121 (33%), Positives = 58/121 (47%), Gaps = 10/121 (8%)
Query: 424 VDAGGRLLTWGWGVHGQLGLGNIDDQW----TPQLVTKFLGRKVQSVGCGACHSVLLTRG 479
+ AGG +GWG + + LG I+ TP L R VQ +G G +T
Sbjct: 121 LSAGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATL-RPVQLIG-GEQTLFAVTAD 178
Query: 480 GELWACGASVFGQLGTGQRGKASLPVRVAL--HEPVRALA--AGYFHNLALTHKGEVYVW 535
G+L+A G G+LG G S P + H ++ +A +G H LAL+ +GEVY W
Sbjct: 179 GKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSW 238
Query: 536 G 536
G
Sbjct: 239 G 239
Score = 36.3 bits (80), Expect = 0.54
Identities = 14/41 (34%), Positives = 24/41 (58%)
Query: 583 VQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIP 623
V +++G H +++ G +Y+WG DG+LG G+R P
Sbjct: 217 VAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRP 257
Score = 32.7 bits (71), Expect = 6.7
Identities = 13/36 (36%), Positives = 21/36 (58%)
Query: 599 GSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQP 634
G+IY WG N GQLG + ++++PT + +P
Sbjct: 127 GTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRP 162
>BC113826-1|AAI13827.1| 244|Homo sapiens RCCD1 protein protein.
Length = 244
Score = 46.8 bits (106), Expect = 4e-04
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
Query: 408 GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGLGNIDDQWTPQLVTKFLGRKVQ--S 465
G+ V + G H+A V G L TWGWG +GQLG + P+ V F+ +++Q +
Sbjct: 167 GSDAVKASCGSRHTAVVTRTGELYTWGWGKYGQLGHEDTTSLDRPRRVEYFVDKQLQVKA 226
Query: 466 VGCG 469
V CG
Sbjct: 227 VTCG 230
Score = 41.9 bits (94), Expect = 0.011
Identities = 21/64 (32%), Positives = 33/64 (51%)
Query: 438 HGQLGLGNIDDQWTPQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQ 497
HGQLG G ++ + P+L+ G + V G HSV ++ G+++ G + GQL
Sbjct: 55 HGQLGHGTLEAELEPRLLEALQGLVMAEVAAGGWHSVCVSETGDIYIWGWNESGQLALPT 114
Query: 498 RGKA 501
R A
Sbjct: 115 RNLA 118
Score = 39.5 bits (88), Expect = 0.058
Identities = 17/51 (33%), Positives = 25/51 (49%)
Query: 583 VQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQ 633
V+ S G H+ ++ G +YTWG GQLG D + P V+ + Q
Sbjct: 171 VKASCGSRHTAVVTRTGELYTWGWGKYGQLGHEDTTSLDRPRRVEYFVDKQ 221
Score = 37.5 bits (83), Expect = 0.23
Identities = 19/56 (33%), Positives = 27/56 (48%)
Query: 452 PQLVTKFLGRKVQSVGCGACHSVLLTRGGELWACGASVFGQLGTGQRGKASLPVRV 507
P L+ +G CG+ H+ ++TR GEL+ G +GQLG P RV
Sbjct: 159 PALLDLPMGSDAVKASCGSRHTAVVTRTGELYTWGWGKYGQLGHEDTTSLDRPRRV 214
Score = 36.3 bits (80), Expect = 0.54
Identities = 16/36 (44%), Positives = 19/36 (52%)
Query: 408 GAPLVCVAAGHYHSAAVDAGGRLLTWGWGVHGQLGL 443
G + VAAG +HS V G + WGW GQL L
Sbjct: 77 GLVMAEVAAGGWHSVCVSETGDIYIWGWNESGQLAL 112
Score = 35.9 bits (79), Expect = 0.72
Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 1/68 (1%)
Query: 582 IVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTEVKIRTETQPHTMKSDS 641
+ +++AG HS ++ G IY WG N GQL R + E R T+ + S
Sbjct: 80 MAEVAAGGWHSVCVSETGDIYIWGWNESGQLALPTRNLAE-DGETVAREATELNEDGSQV 138
Query: 642 EKTTDADE 649
++T A++
Sbjct: 139 KRTGGAED 146
Score = 32.7 bits (71), Expect = 6.7
Identities = 20/49 (40%), Positives = 31/49 (63%), Gaps = 4/49 (8%)
Query: 491 GQLGTGQRGKASLPVRV--ALHEPVRA-LAAGYFHNLALTHKGEVYVWG 536
GQLG G +A L R+ AL V A +AAG +H++ ++ G++Y+WG
Sbjct: 56 GQLGHGTL-EAELEPRLLEALQGLVMAEVAAGGWHSVCVSETGDIYIWG 103
>X54131-1|CAA38066.1| 1997|Homo sapiens protein-tyrosine phosphatase
protein.
Length = 1997
Score = 35.5 bits (78), Expect = 0.95
Identities = 31/117 (26%), Positives = 50/117 (42%), Gaps = 7/117 (5%)
Query: 577 NVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTE--VKIRTETQP 634
NV GR V S I +N S Y+ +++ G +R I + TE + +R ++P
Sbjct: 988 NVVGRTVPASV---QGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTSEP 1044
Query: 635 HTMKSDSEKTTDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTGNTHLQISNEKTK 691
T K K D ++ + L GG F+ +GR T L+I+ T+
Sbjct: 1045 ATTKQ--HKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTR 1099
>BX648771-1|CAE46198.1| 1956|Homo sapiens hypothetical protein
protein.
Length = 1956
Score = 35.5 bits (78), Expect = 0.95
Identities = 31/117 (26%), Positives = 50/117 (42%), Gaps = 7/117 (5%)
Query: 577 NVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTE--VKIRTETQP 634
NV GR V S I +N S Y+ +++ G +R I + TE + +R ++P
Sbjct: 947 NVVGRTVPASV---QGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTSEP 1003
Query: 635 HTMKSDSEKTTDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTGNTHLQISNEKTK 691
T K K D ++ + L GG F+ +GR T L+I+ T+
Sbjct: 1004 ATTKQ--HKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTR 1058
>BC113463-1|AAI13464.1| 1997|Homo sapiens protein tyrosine
phosphatase, receptor type, B protein.
Length = 1997
Score = 35.5 bits (78), Expect = 0.95
Identities = 31/117 (26%), Positives = 50/117 (42%), Gaps = 7/117 (5%)
Query: 577 NVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTE--VKIRTETQP 634
NV GR V S I +N S Y+ +++ G +R I + TE + +R ++P
Sbjct: 988 NVVGRTVPASV---QGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTSEP 1044
Query: 635 HTMKSDSEKTTDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTGNTHLQISNEKTK 691
T K K D ++ + L GG F+ +GR T L+I+ T+
Sbjct: 1045 ATTKQ--HKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTR 1099
>BC101679-1|AAI01680.1| 1997|Homo sapiens protein tyrosine
phosphatase, receptor type, B protein.
Length = 1997
Score = 35.5 bits (78), Expect = 0.95
Identities = 31/117 (26%), Positives = 50/117 (42%), Gaps = 7/117 (5%)
Query: 577 NVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTE--VKIRTETQP 634
NV GR V S I +N S Y+ +++ G +R I + TE + +R ++P
Sbjct: 988 NVVGRTVPASV---QGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTSEP 1044
Query: 635 HTMKSDSEKTTDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTGNTHLQISNEKTK 691
T K K D ++ + L GG F+ +GR T L+I+ T+
Sbjct: 1045 ATTKQ--HKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTR 1099
>AK128562-1|BAC87502.1| 1407|Homo sapiens protein ( Homo sapiens cDNA
FLJ46721 fis, clone TRACH3018524, highly similar to
Protein-tyrosine phosphatase beta precursor (EC
3.1.3.48). ).
Length = 1407
Score = 35.5 bits (78), Expect = 0.95
Identities = 31/117 (26%), Positives = 50/117 (42%), Gaps = 7/117 (5%)
Query: 577 NVRGRIVQISAGWHHSCIINNMGSIYTWGLNFDGQLGSGDRKQIQIPTE--VKIRTETQP 634
NV GR V S I +N S Y+ +++ G +R I + TE + +R ++P
Sbjct: 1085 NVVGRTVPASV---QGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTSEP 1141
Query: 635 HTMKSDSEKTTDADENMEFNTKALVGCGGDFTVYIDDDGRIYSTGNTHLQISNEKTK 691
T K K D ++ + L GG F+ +GR T L+I+ T+
Sbjct: 1142 ATTKQ--HKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTR 1196
>BC031555-1|AAH31555.1| 1024|Homo sapiens NLRC4 protein protein.
Length = 1024
Score = 32.3 bits (70), Expect = 8.8
Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
Query: 122 DGWVARLGVFGRLHELSMFKQSANVGSLGNAAIIVKLLAVLIKMS-TNEEEIFDW 175
DGW+A +GVF L +L F S L + A++ KL VL K++ E + W
Sbjct: 952 DGWLAFMGVFENLKQLVFFDFSTK-EFLPDPALVRKLSQVLSKLTFLQEARLVGW 1005
>AY358152-1|AAQ88519.1| 1024|Homo sapiens CARD12 protein.
Length = 1024
Score = 32.3 bits (70), Expect = 8.8
Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
Query: 122 DGWVARLGVFGRLHELSMFKQSANVGSLGNAAIIVKLLAVLIKMS-TNEEEIFDW 175
DGW+A +GVF L +L F S L + A++ KL VL K++ E + W
Sbjct: 952 DGWLAFMGVFENLKQLVFFDFSTK-EFLPDPALVRKLSQVLSKLTFLQEARLVGW 1005
>AY035391-1|AAK59843.1| 1024|Homo sapiens ICE-protease activating
factor protein.
Length = 1024
Score = 32.3 bits (70), Expect = 8.8
Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
Query: 122 DGWVARLGVFGRLHELSMFKQSANVGSLGNAAIIVKLLAVLIKMS-TNEEEIFDW 175
DGW+A +GVF L +L F S L + A++ KL VL K++ E + W
Sbjct: 952 DGWLAFMGVFENLKQLVFFDFSTK-EFLPDPALVRKLSQVLSKLTFLQEARLVGW 1005
>AY032589-1|AAK38730.1| 1024|Homo sapiens caspase recruitment domain
protein 12 protein.
Length = 1024
Score = 32.3 bits (70), Expect = 8.8
Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
Query: 122 DGWVARLGVFGRLHELSMFKQSANVGSLGNAAIIVKLLAVLIKMS-TNEEEIFDW 175
DGW+A +GVF L +L F S L + A++ KL VL K++ E + W
Sbjct: 952 DGWLAFMGVFENLKQLVFFDFSTK-EFLPDPALVRKLSQVLSKLTFLQEARLVGW 1005
>AY027788-1|AAK14777.1| 359|Homo sapiens CLANB protein.
Length = 359
Score = 32.3 bits (70), Expect = 8.8
Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
Query: 122 DGWVARLGVFGRLHELSMFKQSANVGSLGNAAIIVKLLAVLIKMS-TNEEEIFDW 175
DGW+A +GVF L +L F S L + A++ KL VL K++ E + W
Sbjct: 287 DGWLAFMGVFENLKQLVFFDFSTK-EFLPDPALVRKLSQVLSKLTFLQEARLVGW 340
>AY027787-1|AAK14776.1| 1024|Homo sapiens CLANA protein.
Length = 1024
Score = 32.3 bits (70), Expect = 8.8
Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
Query: 122 DGWVARLGVFGRLHELSMFKQSANVGSLGNAAIIVKLLAVLIKMS-TNEEEIFDW 175
DGW+A +GVF L +L F S L + A++ KL VL K++ E + W
Sbjct: 952 DGWLAFMGVFENLKQLVFFDFSTK-EFLPDPALVRKLSQVLSKLTFLQEARLVGW 1005
>AL389934-1|CAB97523.1| 439|Homo sapiens hypothetical protein,
weakly similar to (AF102871) neuronal apoptosis
inhibitor protein.
Length = 439
Score = 32.3 bits (70), Expect = 8.8
Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
Query: 122 DGWVARLGVFGRLHELSMFKQSANVGSLGNAAIIVKLLAVLIKMS-TNEEEIFDW 175
DGW+A +GVF L +L F S L + A++ KL VL K++ E + W
Sbjct: 367 DGWLAFMGVFENLKQLVFFDFSTK-EFLPDPALVRKLSQVLSKLTFLQEARLVGW 420
>AF376061-1|AAK53443.1| 1024|Homo sapiens caspase recruitment domain
protein 12 protein.
Length = 1024
Score = 32.3 bits (70), Expect = 8.8
Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
Query: 122 DGWVARLGVFGRLHELSMFKQSANVGSLGNAAIIVKLLAVLIKMS-TNEEEIFDW 175
DGW+A +GVF L +L F S L + A++ KL VL K++ E + W
Sbjct: 952 DGWLAFMGVFENLKQLVFFDFSTK-EFLPDPALVRKLSQVLSKLTFLQEARLVGW 1005
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.135 0.421
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 142,026,898
Number of Sequences: 224733
Number of extensions: 5673362
Number of successful extensions: 10747
Number of sequences better than 10.0: 113
Number of HSP's better than 10.0 without gapping: 98
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 8803
Number of HSP's gapped (non-prelim): 1274
length of query: 993
length of database: 73,234,838
effective HSP length: 97
effective length of query: 896
effective length of database: 51,435,737
effective search space: 46086420352
effective search space used: 46086420352
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 70 (32.3 bits)
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