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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000412-TA|BGIBMGA000412-PA|IPR004114|THUMP
         (291 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC000448-1|AAH00448.1|  353|Homo sapiens THUMP domain containing...   179   1e-44
AK000281-1|BAA91050.1|  353|Homo sapiens protein ( Homo sapiens ...   177   5e-44
AC004381-1|AAC31666.1|  242|Homo sapiens Unknown gene product pr...   145   2e-34

>BC000448-1|AAH00448.1|  353|Homo sapiens THUMP domain containing 1
           protein.
          Length = 353

 Score =  179 bits (435), Expect = 1e-44
 Identities = 101/279 (36%), Positives = 161/279 (57%), Gaps = 26/279 (9%)

Query: 21  LEPGFKGFFCTCNFREKDCVKEVYNLLNEYASKLY-PD--LDVEQVPPSAVPXXXXXXXX 77
           LEPG +G   TCN  E+ CV+E Y+LLNEY   +Y P+   D +Q P  +          
Sbjct: 39  LEPGLQGILITCNMNERKCVEEAYSLLNEYGDDMYGPEKFTDKDQQPSGSEGEDDDAEAA 98

Query: 78  XXXXXXXXXXIGDILRREVDSIKKNSQKSLRFKRFQVVETGASNCIFVKTNLPSPEELTT 137
                         L++EV  IK +++  +R +RFQ VE+GA+N +F++T    PE+L  
Sbjct: 99  --------------LKKEVGDIKASTE--MRLRRFQSVESGANNVVFIRTLGIEPEKLVH 142

Query: 138 AIIKDLIATRIQKTRHVMRLLPIMITCKANLPDIMESAGKLFDKYFLKEPT--SFSVVFN 195
            I++D+  T+ +KTR ++R+LPI  TCKA L D+ + A    + +F K P   +F +V+ 
Sbjct: 143 HILQDMYKTKKKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWF-KAPNKGTFQIVYK 201

Query: 196 KRFNNSVSRDLIIKELAELVVVKNRENKADLKNPGLCIIVEVIKGMCLLSIVDNYFTYKK 255
            R N+ V+R+ +I+ELA +V   N ENK DL NP   ++VE+IK +C LS+V +Y  ++K
Sbjct: 202 SRNNSHVNREEVIRELAGIVCTLNSENKVDLTNPQYTVVVEIIKAVCCLSVVKDYMLFRK 261

Query: 256 YNLNEICKEESN----DSEESQAKKFKSSLNSETEEQNT 290
           YNL E+ K   +    +S++   K+ K     ++++ NT
Sbjct: 262 YNLQEVVKSPKDPSQLNSKQGNGKEAKLESADKSDQNNT 300


>AK000281-1|BAA91050.1|  353|Homo sapiens protein ( Homo sapiens
           cDNA FLJ20274 fis, clone HEP02123. ).
          Length = 353

 Score =  177 bits (430), Expect = 5e-44
 Identities = 100/279 (35%), Positives = 161/279 (57%), Gaps = 26/279 (9%)

Query: 21  LEPGFKGFFCTCNFREKDCVKEVYNLLNEYASKLY-PD--LDVEQVPPSAVPXXXXXXXX 77
           LEPG +G   TCN  E+ CV+E Y+LLNEY   +Y P+   D +Q P  +          
Sbjct: 39  LEPGLQGILITCNMNERKCVEEAYSLLNEYGDDMYGPEKFTDKDQRPSGSEGEDDDAEAA 98

Query: 78  XXXXXXXXXXIGDILRREVDSIKKNSQKSLRFKRFQVVETGASNCIFVKTNLPSPEELTT 137
                         L++EV  IK +++  +R +RFQ VE+GA+N +F++T    PE+L  
Sbjct: 99  --------------LKKEVGDIKASTE--MRLRRFQSVESGANNVVFIRTLGIEPEKLVH 142

Query: 138 AIIKDLIATRIQKTRHVMRLLPIMITCKANLPDIMESAGKLFDKYFLKEPT--SFSVVFN 195
            I++D+  T+ +KTR ++R+LPI  TCKA L D+ + A    + +F K P   +F +V+ 
Sbjct: 143 HILQDMYKTKKKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWF-KAPNKGTFQIVYK 201

Query: 196 KRFNNSVSRDLIIKELAELVVVKNRENKADLKNPGLCIIVEVIKGMCLLSIVDNYFTYKK 255
            R N+ V+R+ +I+ELA +V   N ENK DL NP   ++VE+IK +C LS+V +Y  ++K
Sbjct: 202 SRNNSHVNREEVIRELAGIVCTLNSENKVDLTNPQYTVVVEIIKAVCCLSVVKDYMLFRK 261

Query: 256 YNLNEICKEESN----DSEESQAKKFKSSLNSETEEQNT 290
           YNL E+ K   +    +S++   ++ K     ++++ NT
Sbjct: 262 YNLQEVVKSPKDPSQLNSKQGNGEEAKLESADKSDQNNT 300


>AC004381-1|AAC31666.1|  242|Homo sapiens Unknown gene product
           protein.
          Length = 242

 Score =  145 bits (351), Expect = 2e-34
 Identities = 73/190 (38%), Positives = 120/190 (63%), Gaps = 7/190 (3%)

Query: 107 LRFKRFQVVETGASNCIFVKTNLPSPEELTTAIIKDLIATRIQKTRHVMRLLPIMITCKA 166
           +R +RFQ VE+GA+N +F++T    PE+L   I++D+  T+ +KTR ++R+LPI  TCKA
Sbjct: 1   MRLRRFQSVESGANNVVFIRTLGIEPEKLVHHILQDMYKTKKKKTRVILRMLPISGTCKA 60

Query: 167 NLPDIMESAGKLFDKYFLKEPT--SFSVVFNKRFNNSVSRDLIIKELAELVVVKNRENKA 224
            L D+ + A    + +F K P   +F +V+  R N+ V+R+ +I+ELA +V   N ENK 
Sbjct: 61  FLEDMKKYAETFLEPWF-KAPNKGTFQIVYKSRNNSHVNREEVIRELAGIVCTLNSENKV 119

Query: 225 DLKNPGLCIIVEVIKGMCLLSIVDNYFTYKKYNLNEICKEESN----DSEESQAKKFKSS 280
           DL NP   ++VE+IK +C LS+V +Y  ++KYNL E+ K   +    +S++   K+ K  
Sbjct: 120 DLTNPQYTVVVEIIKAVCCLSVVKDYMLFRKYNLQEVVKSPKDPSQLNSKQGNGKEAKLE 179

Query: 281 LNSETEEQNT 290
              ++++ NT
Sbjct: 180 SADKSDQNNT 189


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.318    0.134    0.380 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 34,384,569
Number of Sequences: 224733
Number of extensions: 1220345
Number of successful extensions: 3062
Number of sequences better than 10.0: 3
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 3054
Number of HSP's gapped (non-prelim): 5
length of query: 291
length of database: 73,234,838
effective HSP length: 89
effective length of query: 202
effective length of database: 53,233,601
effective search space: 10753187402
effective search space used: 10753187402
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 65 (30.3 bits)

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