BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000408-TA|BGIBMGA000408-PA|IPR000719|Protein kinase, IPR013543|Calcium/calmodulin dependent protein kinase II, association-domain, IPR011009|Protein kinase-like, IPR008271|Serine/threonine protein kinase, active site, IPR002290|Serine/threonine protein kinase (510 letters) Database: spombe 5004 sequences; 2,362,478 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase... 208 1e-54 SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosac... 190 5e-49 SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schiz... 179 7e-46 SPAC23A1.06c |cmk2|mkp2|MAPK-activated protein kinase Cmk2|Schiz... 178 2e-45 SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosac... 176 7e-45 SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Sch... 164 2e-41 SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |S... 161 2e-40 SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosa... 158 1e-39 SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |S... 154 3e-38 SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|c... 154 3e-38 SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccha... 151 2e-37 SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizos... 144 3e-35 SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosa... 139 7e-34 SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalyt... 138 1e-33 SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosac... 136 7e-33 SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizo... 135 1e-32 SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosacc... 135 2e-32 SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharom... 132 1e-31 SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces ... 131 3e-31 SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase P... 126 6e-30 SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc... 125 1e-29 SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizo... 122 1e-28 SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosacchar... 122 1e-28 SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomy... 121 2e-28 SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosa... 118 1e-27 SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosa... 118 3e-27 SPCC63.08c |ppk36|atg1|serine/threonine protein kinase Ppk36|Sch... 116 8e-27 SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizo... 116 1e-26 SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |S... 115 1e-26 SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1... 115 1e-26 SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces po... 114 3e-26 SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|ch... 113 7e-26 SPCC1322.08 |srk1|mkp1|MAPK-activated protein kinase Srk1|Schizo... 111 2e-25 SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosacc... 111 2e-25 SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosacch... 110 4e-25 SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|... 107 5e-24 SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schiz... 102 1e-22 SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces... 101 2e-22 SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase ... 99 2e-21 SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizo... 98 2e-21 SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccha... 97 7e-21 SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosacch... 97 7e-21 SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2... 95 3e-20 SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyc... 93 6e-20 SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosa... 93 8e-20 SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1||... 92 1e-19 SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Sc... 91 3e-19 SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase ki... 91 3e-19 SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Pp... 91 4e-19 SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schi... 89 2e-18 SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosa... 89 2e-18 SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schiz... 87 7e-18 SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizo... 84 5e-17 SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizos... 82 2e-16 SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizos... 82 2e-16 SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosac... 81 3e-16 SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Sch... 81 3e-16 SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosacchar... 81 4e-16 SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyc... 81 5e-16 SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizos... 79 2e-15 SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein k... 77 8e-15 SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating ... 77 8e-15 SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Sch... 76 1e-14 SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe... 75 2e-14 SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosac... 73 7e-14 SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizos... 73 1e-13 SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity prote... 73 1e-13 SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schi... 72 2e-13 SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Sch... 72 2e-13 SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccha... 68 4e-12 SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizos... 67 6e-12 SPAC823.03 |ppk15||serine/threonine protein kinase Ppk15 |Schizo... 66 8e-12 SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosa... 66 1e-11 SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosa... 66 1e-11 SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase S... 65 3e-11 SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|S... 65 3e-11 SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizos... 64 4e-11 SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |... 62 1e-10 SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gc... 62 1e-10 SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schi... 60 5e-10 SPBC119.07 |ppk19||serine/threonine protein kinase Ppk19|Schizos... 60 7e-10 SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosac... 58 2e-09 SPBC337.04 |ppk27||serine/threonine protein kinase Ppk27 |Schizo... 57 7e-09 SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomy... 56 9e-09 SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomy... 53 8e-08 SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosac... 52 1e-07 SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosacchar... 52 3e-07 SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizos... 50 1e-06 SPAC20G4.03c |hri1||eIF2 alpha kinase Hri1|Schizosaccharomyces p... 50 1e-06 SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk... 48 3e-06 SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces po... 47 5e-06 SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizos... 46 9e-06 SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizos... 43 9e-05 SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizos... 42 2e-04 SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosa... 41 5e-04 SPAC1805.05 |cki3||serine/threonine protein kinase Cki3|Schizosa... 40 6e-04 SPAC12B10.14c |ppk2||serine/threonine protein kinase Ppk2 |Schiz... 40 6e-04 SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizos... 39 0.001 SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizo... 38 0.003 SPBP23A10.10 |ppk32||serine/threonine protein kinase Ppk32 |Schi... 36 0.018 SPBC21C3.18 |spo4||serine/threonine protein kinase Spo4|Schizosa... 35 0.031 SPAC27E2.09 |mak2|phk1|histidine kinase Mak2 |Schizosaccharomyce... 32 0.22 SPAC3H1.13 |ppk13||serine/threonine protein kinase Ppk13 |Schizo... 31 0.50 SPBC530.14c |dsk1||SR protein-specific kinase Dsk1|Schizosacchar... 31 0.50 SPBC29A10.10c |||tRNA-splicing endonuclease positive effector |S... 29 1.5 SPAP27G11.07c |||serine/threonine protein kinase |Schizosaccharo... 28 2.7 SPBC2D10.14c |myo51||myosin type V|Schizosaccharomyces pombe|chr... 27 4.7 SPAC17C9.03 |tif471||translation initiation factor eIF4G |Schizo... 27 6.2 >SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase Cmk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 335 Score = 208 bits (509), Expect = 1e-54 Identities = 116/292 (39%), Positives = 165/292 (56%), Gaps = 6/292 (2%) Query: 17 YELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSAR-DFQKLEREARICRKLQHPN 75 Y + LG G ++ VR AV T +AAKI+N K + + DF K E +HPN Sbjct: 31 YRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKKQDFVKNEIAILKRVSYEHPN 90 Query: 76 IVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNGV 135 I+ L D + + YL+ +L TGGELF+ I A+ + EADA+ ++ +V + H NG+ Sbjct: 91 ILHLVDFFETVNNLYLITELATGGELFDRICAKGSFYEADAAALMRTTTSAVKYLHDNGI 150 Query: 136 VHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFA-GTPGYLSPEVLKKEPY 194 VHRDLKPENLL SK + + +ADFGL+ + Q A GTP Y++PEV ++ Y Sbjct: 151 VHRDLKPENLLYRSKDPNSDLLIADFGLSHFYEDSQYYMLMTACGTPEYMAPEVFRRTGY 210 Query: 195 GKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDTVTPEAKSLINQ 254 GKPVD+WA GVI Y LL GY PF Q + I A Y + P W ++ AK I + Sbjct: 211 GKPVDMWAIGVITYFLLSGYTPFARPSQVEVIEAILANEYTFNDPCWSGISETAKDFIKK 270 Query: 255 MLTVNPSKRITASEALKHPWICHRERVASVMHRQETVDCLKKFNARRKLKGA 306 L +PSKR+TA++ALKHP++ + S + + + FNAR+ + A Sbjct: 271 CLENDPSKRLTAADALKHPFLSEKRPATSNL----LPNVRENFNARKTFRTA 318 >SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosaccharomyces pombe|chr 3|||Manual Length = 460 Score = 190 bits (462), Expect = 5e-49 Identities = 100/272 (36%), Positives = 154/272 (56%), Gaps = 14/272 (5%) Query: 14 SDNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQK-----LEREARIC 68 + +YE+ LG G F++V+ AV+ ++G +A KIIN +K+ +K +RE I Sbjct: 164 NSHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDIL 223 Query: 69 RKLQHPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVH 128 + L HP +V+ H+ + + ++V + V GG+L + ++A E D ++Q+LE++ Sbjct: 224 KSLHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLL 283 Query: 129 HCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEV 188 H H GV HRD+KPEN+L+ + +K++DFGLA + G F GT GYL+PEV Sbjct: 284 HLHKQGVTHRDIKPENILITNDFH---LKISDFGLAKVIHGTGTFLETFCGTMGYLAPEV 340 Query: 189 LKKE------PYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWD 242 LK + Y VDIW+ G +LY++L PF Q + I GAY + Sbjct: 341 LKSKNVNLDGGYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLEN 400 Query: 243 TVTPEAKSLINQMLTVNPSKRITASEALKHPW 274 ++ E LIN+ML +NP KRI+ SEAL+HPW Sbjct: 401 EISEEGIDLINRMLEINPEKRISESEALQHPW 432 >SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schizosaccharomyces pombe|chr 3|||Manual Length = 576 Score = 179 bits (436), Expect = 7e-46 Identities = 100/270 (37%), Positives = 156/270 (57%), Gaps = 11/270 (4%) Query: 7 ESVSTRFSDNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQ-KLEREA 65 E++S R Y ++E LG+G+F V+ A T + A K I+ + L D ++ERE Sbjct: 24 EAISKRHIGPYIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMRVEREI 83 Query: 66 RICRKLQHPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILE 125 + L+HP+I++L+D I +V + GGELF+ IV ++ +E + QQI+ Sbjct: 84 SYLKLLRHPHIIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIIC 142 Query: 126 SVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 185 ++ +CH + +VHRDLKPENLLL VK+ADFGL+ + D G+P Y + Sbjct: 143 AIEYCHRHKIVHRDLKPENLLLDDNLN---VKIADFGLS-NIMTDGNFLKTSCGSPNYAA 198 Query: 186 PEVLKKEPYGKP-VDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDTV 244 PEV+ + Y P VD+W+CG++LY++LVG PF DE L+ ++ + Y P D + Sbjct: 199 PEVINGKLYAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMP----DFL 254 Query: 245 TPEAKSLINQMLTVNPSKRITASEALKHPW 274 +P A+SLI +M+ +P +RIT E + PW Sbjct: 255 SPGAQSLIRRMIVADPMQRITIQEIRRDPW 284 >SPAC23A1.06c |cmk2|mkp2|MAPK-activated protein kinase Cmk2|Schizosaccharomyces pombe|chr 1|||Manual Length = 504 Score = 178 bits (433), Expect = 2e-45 Identities = 106/289 (36%), Positives = 158/289 (54%), Gaps = 28/289 (9%) Query: 15 DNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQHP 74 + Y+L E LG GAFS V +A A K+I +++ + Q + +E I R+++H Sbjct: 63 EKYQLIENLGDGAFSQVYKAYSIDRKEHVAVKVIRKYEMNKKQRQGVFKEVNIMRRVKHK 122 Query: 75 NIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHH-N 133 N+V L D ++ E ++LV +L GGELF IV ++SE A H I Q+ E+V H H Sbjct: 123 NVVNLFDFVETEDFYHLVMELAEGGELFHQIVNFTYFSENLARHIIIQVAEAVKHLHDVC 182 Query: 134 GVVHRDLKPENLL------LASK---AKGAAVKLADFGLAIEVQGDQQ------AWFGFA 178 G+VHRD+KPENLL L S+ D G+ +E G A FGF+ Sbjct: 183 GIVHRDIKPENLLFQPIEYLPSQNYTPPSLEPNKLDEGMFLEGIGAGGIGRILIADFGFS 242 Query: 179 ------------GTPGYLSPEVLKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLY 226 GT GY +PE++ E Y K VD+WA G +L+ +L G+PPF+DE+ L Sbjct: 243 KVVWNSKTATPCGTVGYAAPEIVNDELYSKNVDMWAMGCVLHTMLCGFPPFFDENIKDLA 302 Query: 227 AQIKAGAYDYPSPEWDTVTPEAKSLINQMLTVNPSKRITASEALKHPWI 275 +++ G +++ SP WD ++ AK LI +LTV+P +R + +HPWI Sbjct: 303 SKVVNGEFEFLSPWWDDISDSAKDLITHLLTVDPRERYDIHQFFQHPWI 351 >SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 176 bits (428), Expect = 7e-45 Identities = 104/261 (39%), Positives = 151/261 (57%), Gaps = 16/261 (6%) Query: 17 YELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQHPNI 76 + L + LG G+ S VR A TG A KII + + + E + R L+HPNI Sbjct: 12 WRLGKTLGTGSTSCVRLAKHAKTGDLAAIKIIPIR------YASIGMEILMMRLLRHPNI 65 Query: 77 VRLHDSIQEEHCH-YLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNGV 135 +RL+D + +H H YL + V GELF I SE +A+H + QIL++V HCH Sbjct: 66 LRLYD-VWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQILDAVAHCHRFRF 124 Query: 136 VHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEPY- 194 HRDLK EN+L+ K +K+ADFG+A V+ + + G+ YL+PE++ +PY Sbjct: 125 RHRDLKLENILI--KVNEQQIKIADFGMA-TVEPNDSCLENYCGSLHYLAPEIVSHKPYR 181 Query: 195 GKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDTVTPEAKSLINQ 254 G P D+W+CGVILY LL PF ++ +Y +I+ GAYD PS +++ A+ L+++ Sbjct: 182 GAPADVWSCGVILYSLLSNKLPFGGQNTDVIYNKIRHGAYDLPS----SISSAAQDLLHR 237 Query: 255 MLTVNPSKRITASEALKHPWI 275 ML VNPS RIT E HP++ Sbjct: 238 MLDVNPSTRITIPEVFSHPFL 258 >SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Schizosaccharomyces pombe|chr 2|||Manual Length = 423 Score = 164 bits (399), Expect = 2e-41 Identities = 93/261 (35%), Positives = 149/261 (57%), Gaps = 8/261 (3%) Query: 16 NYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQHPN 75 N+ +K+ +G G+ V+ V TG + A K+I + +++REA + R L+HPN Sbjct: 52 NWIIKKTIGAGSMGKVKLVVNILTGEKAALKMIPFTPNNTSQTVRVQREALLGRLLRHPN 111 Query: 76 IVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNGV 135 I R+ D I+ C Y++F+ V GG+L E I+AR E A Q++ ++ + H N + Sbjct: 112 ICRVIDCIRTPACTYILFEYVPGGQLLEYILARGKLDEDLARSFAMQLINALVYLHKNFI 171 Query: 136 VHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEPY- 194 VHRDLK EN+LL ++ VKL DFGL+ + G+ + +PE+L +PY Sbjct: 172 VHRDLKIENVLLTQDSR--QVKLIDFGLS-NFYSKDDLLRTYCGSLYFAAPELLDAKPYI 228 Query: 195 GKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDTVTPEAKSLINQ 254 G VD+W+ GV++Y+++ G PF D L+++IK+G ++PS ++ + SLI Sbjct: 229 GPEVDVWSLGVVIYVMVCGRVPFDDVSVPMLHSKIKSGKLEFPS----YISEDCCSLIAA 284 Query: 255 MLTVNPSKRITASEALKHPWI 275 ML VNP KR + +A K PW+ Sbjct: 285 MLNVNPRKRCSLEQAAKFPWL 305 >SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 445 Score = 161 bits (392), Expect = 2e-40 Identities = 95/275 (34%), Positives = 150/275 (54%), Gaps = 22/275 (8%) Query: 23 LGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDS 82 LG G FS + A+ +TG ++A KII+ KK+S + F + + E I RKL HPNI++++ Sbjct: 166 LGIGGFSRIYMAMDNNTGGQYACKIIDKKKISTKRFFE-DHEMTILRKLDHPNIIKVNME 224 Query: 83 IQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNGVVHRDLKP 142 E ++ ++VTGG+LF + E + QIL+ + + H ++HRDLK Sbjct: 225 YNSETQFFIFEEMVTGGDLFSYLTKLGTVPEVTTLFIMFQILQGLKYLHEQNIIHRDLKL 284 Query: 143 ENLLLASKAKGA-AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEV--------LKKEP 193 EN+L+AS + + L DFG+A +Q ++ F GTP Y +PE+ ++KE Sbjct: 285 ENILIASSSDTIFRIILTDFGVARCMQKGKRL-STFVGTPEYTAPEIQRLKGRSQVEKEN 343 Query: 194 ---YGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDTVTPEAKS 250 YGK VD+W+ GVI+++LL G P + + +K D+ P W +V+ +AK Sbjct: 344 SSGYGKEVDLWSLGVIMFLLLSGNSPSFADG-------VKEKQVDFRDPVWKSVSRQAKD 396 Query: 251 LINQMLTVNPSKRITASEALKHPWIC-HRERVASV 284 LI+ +L NP R T + L HPW H R+ + Sbjct: 397 LISNLLKTNPPDRFTVKQCLSHPWFARHSSRLTKL 431 >SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosaccharomyces pombe|chr 3|||Manual Length = 355 Score = 158 bits (384), Expect = 1e-39 Identities = 89/261 (34%), Positives = 146/261 (55%), Gaps = 11/261 (4%) Query: 17 YELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQK-LEREARICRKLQHPN 75 +E+ + LGKG F V A +K TG+ A K ++ +L +K + RE I L+H N Sbjct: 89 FEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKN 148 Query: 76 IVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNGV 135 I+RL+ +E YL+ + GEL++ + + +SE AS I Q+ ++ + H V Sbjct: 149 ILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHKKHV 208 Query: 136 VHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEPYG 195 +HRD+KPEN+LL + +KL+DFG ++ +++ GT YL PE+++ + + Sbjct: 209 IHRDIKPENILLGIDGE---IKLSDFGWSVHAPSNRRT--TLCGTLDYLPPEMVEGKEHT 263 Query: 196 KPVDIWACGVILYILLVGYPPFWDEDQY-RLYAQIKAGAYDYPSPEWDTVTPEAKSLINQ 254 + VD+W+ GV+ Y LVG PPF D + Y +I PS V P+A+ LI++ Sbjct: 264 EKVDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKIPS----FVPPDARDLISR 319 Query: 255 MLTVNPSKRITASEALKHPWI 275 +L NP KR++ + ++HPWI Sbjct: 320 LLQHNPEKRMSLEQVMRHPWI 340 >SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 891 Score = 154 bits (373), Expect = 3e-38 Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 28/280 (10%) Query: 16 NYELKEELGKGAFSIVRRAVQKSTGYEFAAKIIN------TKKLSARDFQKLE------- 62 NY L + +G G+ V+ A TG +FA KI+ TK +A + + Sbjct: 124 NYVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEATKAAQSEKN 183 Query: 63 ------REARICRKLQHPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADA 116 REA + L+HP I D +Y+VF+ V GG++ + I++ E A Sbjct: 184 KEIRTVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEKQA 243 Query: 117 SHCIQQILESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFG 176 ++QI ++ + H N VVHRDLK EN+L+ +K +K+ DFGL+ + Q Sbjct: 244 RKFVRQIGSALSYLHQNSVVHRDLKIENILI---SKTGDIKIIDFGLS-NLYRRQSRLRT 299 Query: 177 FAGTPGYLSPEVLKKEPY-GKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYD 235 F G+ + +PE+L +PY G VD+W+ G++LY+L+ G PF D++ L+A+IK G + Sbjct: 300 FCGSLYFAAPELLNAQPYIGPEVDVWSFGIVLYVLVCGKVPFDDQNMSALHAKIKKGTVE 359 Query: 236 YPSPEWDTVTPEAKSLINQMLTVNPSKRITASEALKHPWI 275 YPS ++ + K L+++ML +P KR T E L HPW+ Sbjct: 360 YPS----YLSSDCKGLLSRMLVTDPLKRATLEEVLNHPWM 395 >SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|chr 1|||Manual Length = 683 Score = 154 bits (373), Expect = 3e-38 Identities = 90/266 (33%), Positives = 150/266 (56%), Gaps = 10/266 (3%) Query: 23 LGKGAFSIVRRAVQKSTGYEFAAKIINTKKL-SARDFQKLEREARICRKLQHPNIVRLHD 81 +G+G F+ R V+ + G +AAK+I + L + + KL E ++ + + HPNIV D Sbjct: 47 IGEGGFARCFR-VKDNYGNIYAAKVIAKRSLQNDKTKLKLFGEIKVHQSMSHPNIVGFID 105 Query: 82 SIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNGVVHRDLK 141 ++ YL+ +L L E + R+ +E + + + QIL ++ + H V+HRDLK Sbjct: 106 CFEDSTNIYLILELCEHKSLMELLRKRKQLTEPEVRYLMMQILGALKYMHKKRVIHRDLK 165 Query: 142 PENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVL--KKEPYGKPVD 199 N++L VK+ DFGLA + D++ GTP Y++PE+L KE + VD Sbjct: 166 LGNIMLDESNN---VKIGDFGLAALLMDDEERKMTICGTPNYIAPEILFNSKEGHSFEVD 222 Query: 200 IWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDTVTPEAKSLINQMLTVN 259 +W+ GV++Y LL+G PPF D++ +Y +IKA +Y +PS ++ EAK LI+ +LT + Sbjct: 223 LWSAGVVMYALLIGKPPFQDKEVKTIYRKIKANSYSFPSNV--DISAEAKDLISSLLTHD 280 Query: 260 PSKRITASEALKHPWICHRERVASVM 285 PS R + + + H + H +AS + Sbjct: 281 PSIRPSIDDIVDHEFF-HTGYMASTL 305 >SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 151 bits (366), Expect = 2e-37 Identities = 87/261 (33%), Positives = 148/261 (56%), Gaps = 10/261 (3%) Query: 17 YELKEELGKGAFSIVRRAVQKSTGYEFAAK-IINTKKLSARDFQKLEREARICRKLQHPN 75 +EL LG G + R A + TG K I+ +L++ ++E E + R ++HPN Sbjct: 10 WELGLSLGSGGPNSSRLAKHRETGQLAVVKPIVGWSELTSSQQARIEGELVLLRLIEHPN 69 Query: 76 IVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNGV 135 +++L D I + ++V + + GGELF+ ++ + ++E D + + QIL + +CH + Sbjct: 70 VLQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLWQILCGLEYCHKLHI 129 Query: 136 VHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEPY- 194 HRDLKPENL L A G ++K+ +FG+A +Q + G+P Y SPE++ Y Sbjct: 130 CHRDLKPENLYL--DAHG-SIKIGEFGMA-SIQQPGKLLQTSCGSPHYASPEIIMGRSYD 185 Query: 195 GKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDTVTPEAKSLINQ 254 G DIW+CG+I + LL G PF D++ L ++ G ++ PS ++P+A+ L+ + Sbjct: 186 GCASDIWSCGIIFFALLTGKLPFDDDNIRSLLLKVCQGQFEMPS----NISPQAQHLLYR 241 Query: 255 MLTVNPSKRITASEALKHPWI 275 ML V+ S RIT + +HP++ Sbjct: 242 MLDVDSSTRITMEQIREHPFL 262 >SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizosaccharomyces pombe|chr 1|||Manual Length = 532 Score = 144 bits (349), Expect = 3e-35 Identities = 89/258 (34%), Positives = 134/258 (51%), Gaps = 11/258 (4%) Query: 19 LKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARD-FQKLEREARICRKLQHPNIV 77 L LG+G + V+ T + A K++ +L +D +++L+RE I R+L HPNI+ Sbjct: 25 LGRTLGQGNLAKVKLGKHFQTNEKVALKMVYNDELEDKDTWKRLQREVTILRQLHHPNII 84 Query: 78 RLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNGVVH 137 L+ + L + + +L +V E +QI+ ++ +CH + V H Sbjct: 85 TLYQVFRVPKYTVLALEYMDT-DLHSMVVKHNRLDECTTRKIFRQIVHAIDYCHLHRVAH 143 Query: 138 RDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEPY-GK 196 RDLK EN+LL K VKL DFGL+ D GTP Y +PEV++ Y G Sbjct: 144 RDLKLENILLN---KDLVVKLTDFGLS-NFMLDGSFLSTSCGTPHYAAPEVIQGRYYDGC 199 Query: 197 PVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDTVTPEAKSLINQML 256 VD+W CG++LY++LVG PF D + +++ G Y PS V+ A LI QML Sbjct: 200 DVDVWGCGILLYLMLVGEFPFEDVTISNVLSRVCKGIYTIPS----FVSSSASDLIRQML 255 Query: 257 TVNPSKRITASEALKHPW 274 V P+ RI +E ++HPW Sbjct: 256 MVLPTSRIKVAEIMQHPW 273 >SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosaccharomyces pombe|chr 3|||Manual Length = 592 Score = 139 bits (337), Expect = 7e-34 Identities = 92/280 (32%), Positives = 145/280 (51%), Gaps = 26/280 (9%) Query: 12 RFSDNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQK---LEREARIC 68 R SD ++ E LG+G++S V A + ST E+A K+++ + + +K +E+EA +C Sbjct: 95 RVSD-FKFGEILGEGSYSTVLTATENSTKREYAIKVLDKRHIIKEKKEKYVNIEKEA-LC 152 Query: 69 RKLQHPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVH 128 +HP ++L + Q+ H Y V L GEL + I ++E A + I++S+ Sbjct: 153 ILSKHPGFIKLFYTFQDAHNLYFVLSLARNGELLDYINKLGRFNEICAQYYAALIVDSID 212 Query: 129 HCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGD--------------QQAW 174 + H GV+HRDLKPEN+LL + K+ DFG A + Q Sbjct: 213 YMHGRGVIHRDLKPENILLDDNMR---TKITDFGSAKILNSSHGSHEEDTHHADKPQAHS 269 Query: 175 FGFAGTPGYLSPEVLKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAY 234 F GT Y+SPEVL + G DIWA G IL+ +L G PPF ++Y + I +Y Sbjct: 270 RSFVGTARYVSPEVLSDKIAGTASDIWAFGCILFQMLAGKPPFVAGNEYLTFQSILHLSY 329 Query: 235 DYPSPEWDTVTPEAKSLINQMLTVNPSKRITASEALKHPW 274 + P P+ ++ A LI ++L ++P R+T E +HP+ Sbjct: 330 EIP-PD---ISDVASDLIKKLLVLDPKDRLTVDEIHQHPF 365 >SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalytic subunit Pka1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 512 Score = 138 bits (335), Expect = 1e-33 Identities = 81/263 (30%), Positives = 130/263 (49%), Gaps = 11/263 (4%) Query: 16 NYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLER---EARICRKLQ 72 ++ + LG G+F V +A K++ KK+ D +++E E I ++Q Sbjct: 200 DFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIV--DMKQIEHTCDERYILSRVQ 257 Query: 73 HPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHH 132 HP I L + Q+ ++V D GGELF + + E A +++ ++ + HH Sbjct: 258 HPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILALDYLHH 317 Query: 133 NGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKE 192 N +V+RDLKPENLLL + +K+ DFG A V GTP YL+PE++ + Sbjct: 318 NQIVYRDLKPENLLLD---RFGHLKIVDFGFAKRVSTSNCCTL--CGTPDYLAPEIISLK 372 Query: 193 PYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDTVTPEAKSLI 252 PY K D W+ G++++ +L GYPPF+ E+ +LY I G +YPS L+ Sbjct: 373 PYNKAADWWSLGILIFEMLAGYPPFYSENPMKLYENILEGKVNYPSYFSPASIDLLSHLL 432 Query: 253 NQMLTVNPSKRITAS-EALKHPW 274 + +T S + + HPW Sbjct: 433 QRDITCRYGNLKDGSMDIIMHPW 455 >SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosaccharomyces pombe|chr 3|||Manual Length = 436 Score = 136 bits (329), Expect = 7e-33 Identities = 82/246 (33%), Positives = 132/246 (53%), Gaps = 10/246 (4%) Query: 23 LGKGAFSIVRRAVQKSTGYEFAAKIINTKK--LSARDFQKLEREARICRKLQHPNIVRLH 80 LG+G++ V QK+TG FA K + L A+ ++ + E +I +++HP I RL+ Sbjct: 97 LGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKGLEQTKNERQILEEVRHPFICRLY 156 Query: 81 DSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNGVVHRDL 140 + Q+ YL+ GGELF + + E + ++ ++ H H G+V+RDL Sbjct: 157 YAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTAELTLALIHLHKLGIVYRDL 216 Query: 141 KPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEPYGKPVDI 200 KPEN LL A+G + L DFGL+ +V + F GT Y +PE+L ++PY VD Sbjct: 217 KPENCLL--DAEG-HILLTDFGLS-KVAENGADCRSFVGTEEYCAPEILLEQPYDHAVDW 272 Query: 201 WACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDTVTPEAKSLINQMLTVNP 260 W+ G++++ LL G PPF + R+ +I + P VT +A+ +IN+ L NP Sbjct: 273 WSMGILIFDLLTGSPPFTANNHKRIMEKITRAKPNIPF----YVTSDARDIINKFLKKNP 328 Query: 261 SKRITA 266 +R+ A Sbjct: 329 KQRLGA 334 >SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizosaccharomyces pombe|chr 3|||Manual Length = 569 Score = 135 bits (327), Expect = 1e-32 Identities = 90/275 (32%), Positives = 135/275 (49%), Gaps = 13/275 (4%) Query: 4 PNRESVSTRFSDNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSAR-DFQKLE 62 PN+ + T D +EL + +GKG+F V + ++ T +A K + + +R + Sbjct: 219 PNQSTPLT--IDAFELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRSEVDHTL 276 Query: 63 REARICRKLQHPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQ 122 E + ++ +P IV L S Q YLV V GGELF + + A I + Sbjct: 277 AERTVLAQVNNPFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAE 336 Query: 123 ILESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPG 182 +L ++ H V++RDLKPEN+LL + L DFGL F GTP Sbjct: 337 LLVALECLHEFNVIYRDLKPENILLDYTGH---IALCDFGLCKLNMAKTDRTNTFCGTPE 393 Query: 183 YLSPEVLKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWD 242 YL+PE+L Y K VD W GV+LY ++ G PPF+DE+ +Y +I +P D Sbjct: 394 YLAPELLLGHGYTKVVDWWTLGVLLYEMITGLPPFYDENINEMYRKILQDPLRFP----D 449 Query: 243 TVTPEAKSLINQMLTVNPSKRI---TASEALKHPW 274 + +AK L++ +LT P KR+ A E HP+ Sbjct: 450 NIDEKAKDLLSGLLTRAPEKRLGSGGAQEIKNHPF 484 >SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 658 Score = 135 bits (326), Expect = 2e-32 Identities = 78/265 (29%), Positives = 138/265 (52%), Gaps = 9/265 (3%) Query: 22 ELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHD 81 ++G+GA V A Q T A K +N + ++F + E + + H NIV D Sbjct: 391 KIGQGASGDVYSARQVGTNLSVAIKKMNINQQPKKEF--IVNEILVMKSHHHKNIVNFID 448 Query: 82 SIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNGVVHRDLK 141 + + ++V + + GG L E +V SE + ++ LE + H H NG+VHRD+K Sbjct: 449 TFFYKSELWMVMEYMRGGSLTE-VVTNNTLSEGQIAAICKETLEGLQHLHENGIVHRDIK 507 Query: 142 PENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEPYGKPVDIW 201 +N+LL+ + +KL DFG ++ + GTP +++PEV+ ++ YG VD+W Sbjct: 508 SDNILLSLQGD---IKLTDFGFCAQIDSNMTKRTTMVGTPYWMAPEVVTRKEYGFKVDVW 564 Query: 202 ACGVILYILLVGYPPFWDEDQYR-LYAQIKAGAYDYPSPEWDTVTPEAKSLINQMLTVNP 260 + G++ ++ G PP+ +E+ R LY G PE ++ +++ LTVNP Sbjct: 565 SLGIMAIEMVEGEPPYLNENPLRALYLIATIGTPKISRPE--LLSSVFHDFLSKSLTVNP 622 Query: 261 SKRITASEALKHPWICHRERVASVM 285 +R ++ E L+HP++ V+S++ Sbjct: 623 KQRPSSGELLRHPFLKQAVPVSSLI 647 >SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharomyces pombe|chr 2|||Manual Length = 1016 Score = 132 bits (318), Expect = 1e-31 Identities = 83/269 (30%), Positives = 139/269 (51%), Gaps = 17/269 (6%) Query: 15 DNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARD-FQKLEREARI---CRK 70 +++ LGKG F V A KS +A K++ + + D + + E R+ + Sbjct: 681 EDFTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDEVESTKSEKRVFLVANR 740 Query: 71 LQHPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHC 130 +HP +V LH Q E Y V D V+GG+L I +F S A ++ ++ + Sbjct: 741 ERHPFLVNLHSCFQTETRIYFVMDFVSGGDLMLHIQQEQF-SRRRAQFYAAEVCLALKYF 799 Query: 131 HHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLK 190 H NG+++RDLK +N+LL+ VK+AD+GL E F GTP +++PE+L Sbjct: 800 HDNGIIYRDLKLDNILLSPDGH---VKVADYGLCKEDMWHDNTTATFCGTPEFMAPEILL 856 Query: 191 KEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDTVTPEAKS 250 ++ Y + VD WA GV++Y +L+G PF ED+ ++ I + YP + ++ S Sbjct: 857 EQQYTRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILSDEPLYPI----HMPRDSVS 912 Query: 251 LINQMLTVNPSKRI-----TASEALKHPW 274 ++ Q+LT +P KR+ A + + HP+ Sbjct: 913 ILQQLLTRDPKKRLGSGPNDAEDVMTHPF 941 >SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces pombe|chr 3|||Manual Length = 496 Score = 131 bits (316), Expect = 3e-31 Identities = 85/273 (31%), Positives = 141/273 (51%), Gaps = 24/273 (8%) Query: 17 YELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKK----LSARDF-QKLEREARICRKL 71 Y + E+G GAF+ VR + +A K +N K ++A + +++ E ++ + Sbjct: 10 YHIGREIGTGAFASVRLCYDDNAKI-YAVKFVNKKHATSCMNAGVWARRMASEIQLHKLC 68 Query: 72 Q-HPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHC 130 H NI+ +++ + ++V + GG+LF+ I E A Q++E + Sbjct: 69 NGHKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQLMEGISFM 128 Query: 131 HHNGVVHRDLKPENLLLASKAKGAAVKLADFGLA--IEVQGDQQAWFGFAGTPGYLSPEV 188 H GV HRDLKPEN+LL +K++DFG A +G + G+P Y +PE+ Sbjct: 129 HSKGVAHRDLKPENILLDYNGN---LKISDFGFASLFSYKGKSRLLNSPVGSPPYAAPEI 185 Query: 189 LKKEPYGKPVDIWACGVILYILLVGYPPFWDE-----DQYRLY-AQIKAGAYDYPSPEWD 242 ++ G VD+W+CG+IL+ LL+G P WDE Y LY Q + +Y +P W+ Sbjct: 186 TQQYD-GSKVDVWSCGIILFALLLGNTP-WDEAISNTGDYLLYKKQCERPSY-HP---WN 239 Query: 243 TVTPEAKSLINQMLTVNPSKRITASEALKHPWI 275 ++P A S+I ML +P KR + ++HPW+ Sbjct: 240 LLSPGAYSIITGMLRSDPFKRYSVKHVVQHPWL 272 >SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase Ppk21|Schizosaccharomyces pombe|chr 2|||Manual Length = 550 Score = 126 bits (305), Expect = 6e-30 Identities = 80/269 (29%), Positives = 132/269 (49%), Gaps = 18/269 (6%) Query: 16 NYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARD---FQKLEREARICRKLQ 72 +Y + +G G+FS VRRA K + E+A K+++ K + + + +ER++ + R Sbjct: 53 DYVFGDIIGDGSFSKVRRATDKKSWKEYAIKVLDKKYIVKENKVKYVNIERDSMM-RLNG 111 Query: 73 HPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHH 132 P I RL + Q++ Y V +L GEL + I F E +IL S+ + H Sbjct: 112 FPGISRLFHTFQDDLKLYYVLELAPNGELLQYIKKYRFLDENCVRFYAAEILSSIEYMHS 171 Query: 133 NGVVHRDLKPENLLLASKAKGAAVKLADFGLA-----IEVQGDQQAWF--GFAGTPGYLS 185 G++HRDLKPEN+L VK+ DFG A V F F GT Y++ Sbjct: 172 CGIIHRDLKPENILFDGNMH---VKITDFGTAKILPPKYVNSPDYTTFPSSFVGTAEYVA 228 Query: 186 PEVLKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDTVT 245 PE+L ++ K D+WA ++Y ++VG PPF + ++ +I + Y+ P + Sbjct: 229 PELLSRQVVSKSSDLWAFACVVYQMIVGSPPFHGSNPNNIFKKIMSLEYELPK----LLP 284 Query: 246 PEAKSLINQMLTVNPSKRITASEALKHPW 274 P+ L + + + PS R T + + P+ Sbjct: 285 PDIVPLFSHLFRIQPSDRSTTQQIKQFPF 313 >SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc7|Schizosaccharomyces pombe|chr 2|||Manual Length = 1062 Score = 125 bits (302), Expect = 1e-29 Identities = 84/293 (28%), Positives = 141/293 (48%), Gaps = 19/293 (6%) Query: 23 LGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDS 82 LGKGAF V R + G A K + K+ D ++ E + + L HPNIV+ S Sbjct: 15 LGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNLDHPNIVKYRGS 74 Query: 83 IQEEHCHYLVFDLVTGGELFEDIVAREF--YSEADASHCIQQILESVHHCHHNGVVHRDL 140 Q ++ + G L + + F E + Q+L+ + + H+ GV+HRD+ Sbjct: 75 YQTNDSLCIILEYCENGSLRS--ICKNFGKIPENLVALYTFQVLQGLLYLHNQGVIHRDI 132 Query: 141 KPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEPYGKPVDI 200 K N+L K +KLADFG+A ++ + G+P +++PEV++ DI Sbjct: 133 KGANIL---TTKDGTIKLADFGVATKINALED--HSVVGSPYWMAPEVIELVGATTASDI 187 Query: 201 WACGVILYILLVGYPPFWDED-QYRLYAQIKAGAYDYPSPEWDTVTPEAKSLINQMLTVN 259 W+ G + LL G PP++D D L+ +K D P ++ AKS + Q + Sbjct: 188 WSVGCTVIELLDGNPPYYDLDPTSALFRMVK----DEHPPLPSNISSAAKSFLMQCFQKD 243 Query: 260 PSKRITASEALKHPWICHRERVASVMHRQETVDCLKKFNARRKLKGAILTTML 312 P+ RI + LKHPW+ + + + +D ++K+N R +K + LT ++ Sbjct: 244 PNLRIKTRKLLKHPWVIMNQTSSKF---SDAIDEVQKYNER--VKESTLTAII 291 >SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizosaccharomyces pombe|chr 1|||Manual Length = 646 Score = 122 bits (294), Expect = 1e-28 Identities = 88/269 (32%), Positives = 131/269 (48%), Gaps = 15/269 (5%) Query: 15 DNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARD---FQKLEREARI-CRK 70 D++ + +GKG F V +K T +A K+++ K + R ER+ + Sbjct: 264 DDFVPLKLIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRRKEVAHTVGERDILVQTSA 323 Query: 71 LQHPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHC 130 P IV L S Q YLV D + GGELF + + E A I ++L ++ Sbjct: 324 ADSPFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAELLLALQAL 383 Query: 131 HHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLK 190 H G+V+RDLKPEN+LL + + L DFGL+ F GT YL+PEV+ Sbjct: 384 HKRGIVYRDLKPENILLDVQGH---IALCDFGLSKANLSVGTTTRTFCGTTDYLAPEVIL 440 Query: 191 KEP-YGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDTVTPEAK 249 E Y VD W+ GV+LY + G+ PF+ ++ +LY I G +P ++ EA+ Sbjct: 441 DEAGYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFGKVRFPR---GLLSVEAR 497 Query: 250 SLINQMLTVNPSKRITA----SEALKHPW 274 LI +L NP R+ A E +KHP+ Sbjct: 498 DLIKLLLNRNPKHRLGAHGDVEEVMKHPF 526 >SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosaccharomyces pombe|chr 1|||Manual Length = 988 Score = 122 bits (294), Expect = 1e-28 Identities = 82/281 (29%), Positives = 141/281 (50%), Gaps = 17/281 (6%) Query: 3 NPNRESVSTRFSDNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKK-LSARDFQKL 61 +P RE + D++ LGKG F V A K +A K++ + L + + L Sbjct: 650 SPRREKKNRVTLDDFTFLAVLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAILKNEELESL 709 Query: 62 EREARI---CRKLQHPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASH 118 + E + K +HP ++ L S Q Y V + + GG+L I ++F S A Sbjct: 710 KTEKHVFEVANKEKHPFLLNLFASFQTSTRVYFVMEYILGGDLMVHIQRQQF-SVKRARF 768 Query: 119 CIQQILESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFA 178 ++ ++ + H NG+ +RDLK +N+LL +++AD+GL E F Sbjct: 769 YGAEVCLALKYFHENGIAYRDLKLDNILLCPDGH---IRIADYGLCKENMLLGNTTSTFC 825 Query: 179 GTPGYLSPEVLKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPS 238 GTP +++PE+L ++ Y K VD WA GV++Y +L+G PF ED+ ++ I + +P Sbjct: 826 GTPEFMAPEILLEQQYSKDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSDEPLFPI 885 Query: 239 PEWDTVTPEAKSLINQMLTVNPSKRI-----TASEALKHPW 274 + +A SL+ +LT +P++R+ A+E + HP+ Sbjct: 886 ----NMPADAVSLLRGLLTRDPNQRLGSGPKDANEVMAHPF 922 >SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 589 Score = 121 bits (292), Expect = 2e-28 Identities = 83/279 (29%), Positives = 139/279 (49%), Gaps = 18/279 (6%) Query: 17 YELKEELGKGAFSIVRRAVQ---KSTGYEFAAKIINTKKLSARDFQKLE-REARICRKLQ 72 + +K +LG+GA V A K G F + I + L + ++L E + R+ Sbjct: 309 FNVKHKLGQGASGSVYLAKVVGGKQLGI-FDSVAIKSIDLQCQTRKELILNEITVMRESI 367 Query: 73 HPNIVRLHDS--IQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHC 130 HPNIV DS ++E H ++V + + G L DI+ + +EA + + + + H Sbjct: 368 HPNIVTYLDSFLVRERHL-WVVMEYMNAGSL-TDIIEKSKLTEAQIARICLETCKGIQHL 425 Query: 131 HHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLK 190 H ++HRD+K +N+LL + +K+ DFG + GTP +++PEV+K Sbjct: 426 HARNIIHRDIKSDNVLLDNSGN---IKITDFGFCARLSNRTNKRVTMVGTPYWMAPEVVK 482 Query: 191 KEPYGKPVDIWACGVILYILLVGYPPFWDEDQYR-LYAQIKAGAYDYPSPEWDTVTPEAK 249 + YG VDIW+ G+++ ++ PP+ ED R LY K G P + V+ K Sbjct: 483 QNEYGTKVDIWSLGIMIIEMIENEPPYLREDPIRALYLIAKNGTPTLKKP--NLVSKNLK 540 Query: 250 SLINQMLTVNPSKRITASEALKHPWI---CHRERVASVM 285 S +N LT++ R TA+E L H ++ C E + S++ Sbjct: 541 SFLNSCLTIDTIFRATAAELLTHSFLNQACPTEDLKSII 579 >SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosaccharomyces pombe|chr 3|||Manual Length = 652 Score = 118 bits (285), Expect = 1e-27 Identities = 84/284 (29%), Positives = 139/284 (48%), Gaps = 26/284 (9%) Query: 12 RFSDNYELKEELGKGAFSIVRRAVQKSTGYEFAAKII----NTKKL----SARDFQKLER 63 ++ ++YE+ +ELG+G V+ T A KII KL ++ +K+ R Sbjct: 130 KYINHYEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKTERRPKLGRANASSQKEKVRR 189 Query: 64 EARICRKLQHPNIVRLHDSIQEEHCH--YLVFDLVTGGELFEDIVAREFYSEADASHCIQ 121 E I +K HPN+VRL + I + YLV + ++GGE+ S ++A + Sbjct: 190 EIAILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISEARQYFR 249 Query: 122 QILESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLA----IEVQGDQQAWFG- 176 ++ + + H+ G++HRD+KP NLLL S VK++DFG++ + D Sbjct: 250 DVVLGLEYLHYQGIIHRDIKPANLLLNS---SNCVKISDFGVSYIANAGLNEDNDVELAK 306 Query: 177 FAGTPGYLSPEVL------KKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIK 230 GTP + +PE+ + + +D+WA GV L+ LL G PF +Y L+ +I Sbjct: 307 TVGTPAFFAPELCWTDLDRPRPKISEAIDVWALGVTLFCLLFGRCPFNASMEYELFDKIV 366 Query: 231 AGAYDYPSPEWDTVTPEAKSLINQMLTVNPSKRITASEALKHPW 274 + PS + E + L+ ++L +P +RIT E HPW Sbjct: 367 NERLNIPST--PDIGEEGRDLLKRLLCKDPEQRITLVEVKLHPW 408 >SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosaccharomyces pombe|chr 1|||Manual Length = 696 Score = 118 bits (283), Expect = 3e-27 Identities = 85/262 (32%), Positives = 132/262 (50%), Gaps = 17/262 (6%) Query: 23 LGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKL----EREARICRKL-QHPNIV 77 +GKG F V + T +A K I+ KKL R + ER + L + P IV Sbjct: 308 IGKGTFGQVYLVRKNDTNRIYAMKKIS-KKLIVRKKEVTHTLGERNILVRTSLDESPFIV 366 Query: 78 RLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNGVVH 137 L S Q YL+ D ++GGELF + + E A I +++ ++ H H + +++ Sbjct: 367 GLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIAELVLALEHLHKHDIIY 426 Query: 138 RDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEP-YGK 196 RDLKPEN+LL A G + L DFGL+ F GT YL+PEVL ++ Y K Sbjct: 427 RDLKPENILL--DADG-HIALCDFGLSKANLSANATTNTFCGTTEYLAPEVLLEDKGYTK 483 Query: 197 PVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDTVTPEAKSLINQML 256 VD W+ GV+++ + G+ PF+ D ++Y I G +P ++ E +S + +L Sbjct: 484 QVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFGKVRFPK---GVLSSEGRSFVRGLL 540 Query: 257 TVNPSKRITA----SEALKHPW 274 NP+ R+ A +E +HP+ Sbjct: 541 NRNPNHRLGAVADTTELKEHPF 562 >SPCC63.08c |ppk36|atg1|serine/threonine protein kinase Ppk36|Schizosaccharomyces pombe|chr 3|||Manual Length = 830 Score = 116 bits (279), Expect = 8e-27 Identities = 83/284 (29%), Positives = 134/284 (47%), Gaps = 37/284 (13%) Query: 17 YELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQHPNI 76 Y ++ E+G+G+F+IV + T + K + TKKL+ + + LE E I ++++H ++ Sbjct: 14 YVIRSEIGRGSFAIVYKGKHTETNRVISIKSVLTKKLTKKLLENLESEISILKEIRHVHV 73 Query: 77 VRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYS---------------------EAD 115 V L D I+ +LV + + G+L I RE ++ E Sbjct: 74 VELIDCIKAGRFIHLVMEYCSLGDLSYFIRKREKFNSIPSLAWINIDHPPVYKAGLNETL 133 Query: 116 ASHCIQQILESVHHCHHNGVVHRDLKPENLLLASKAKGA---------------AVKLAD 160 H QQ+ ++ ++HRD+KP+NLLL A +KLAD Sbjct: 134 VRHFTQQLASALQFLRSRSLIHRDVKPQNLLLQPPPTAAYLEEHPQFVGSPKLPMLKLAD 193 Query: 161 FGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEPYGKPVDIWACGVILYILLVGYPPFWDE 220 FG A +Q A G+P Y++PE+L+ E Y D+W+ G +LY + VG PPF Sbjct: 194 FGFARYLQTSSMAET-LCGSPLYMAPEILRYEKYDAKADLWSVGAVLYEMAVGKPPFKAP 252 Query: 221 DQYRLYAQIKAGAYDYPSPEWDTVTPEAKSLINQMLTVNPSKRI 264 + L +I+ PE + P+ K+LI +L NP+ RI Sbjct: 253 NHVELLRRIQKAKDVIKFPEEAFIHPDIKTLICALLKQNPADRI 296 >SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizosaccharomyces pombe|chr 3|||Manual Length = 338 Score = 116 bits (278), Expect = 1e-26 Identities = 83/290 (28%), Positives = 141/290 (48%), Gaps = 27/290 (9%) Query: 5 NRESVSTRFSDNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLERE 64 N ESVS ++++ +GKG++S V + T FA K IN KK +KL E Sbjct: 23 NFESVS-----QFKIRNVIGKGSWSTVFVVKHRQTKQRFALKCINKKKHDEHKIKKLRNE 77 Query: 65 ARICRKLQHPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQIL 124 + + L HP + + + ++E YLV DL+ GG+L I R+F +E+ + +++ Sbjct: 78 VLLLQSLNHPLLCKFYSEFEDETKIYLVTDLMLGGDLRYHISQRKF-NESVIRIWMVELV 136 Query: 125 ESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQ-----GDQQAWFGFAG 179 ++ + H GV+HRD+KP+N+LL K KLADF +A +V G G Sbjct: 137 SALIYIHSKGVLHRDVKPDNILLDEKGH---CKLADFNVAAKVHTSSSPSKSNMTVGRVG 193 Query: 180 TPGYLSPEVLKKEPYGKPVDIWACGVILYILLVGYPPF-------W----DEDQYRLYAQ 228 TP Y++PE L K D W+ G+ Y L PF W +E++ + Sbjct: 194 TPVYMAPETLIHAVSYKESDWWSLGITFYECLFQVRPFPNHLLINWIRASEEEKASSADR 253 Query: 229 IKAGAYDYPSPEWDTVTPEAKSLINQMLTVNPSKRI--TASEALKHPWIC 276 + + + + T++ +A+S + L ++ KR+ ++ + HP+ C Sbjct: 254 LSSALHISRDKKLTTISKDARSAVMAFLEMDIKKRLGHSSKKLQTHPFFC 303 >SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |Schizosaccharomyces pombe|chr 1|||Manual Length = 672 Score = 115 bits (277), Expect = 1e-26 Identities = 83/268 (30%), Positives = 130/268 (48%), Gaps = 18/268 (6%) Query: 12 RFSD--NYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICR 69 R SD Y ++ +G+G+F V A T + K K+ L RE R Sbjct: 24 RISDVGTYRIESVVGEGSFGKVYLAAHLLTNTKVVLKSSCRKQAII-----LAREIHHHR 78 Query: 70 KLQHPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHH 129 +L HPNI RL++ + E YL + GEL++ + + E + Q+ ++ + Sbjct: 79 RLLHPNITRLYEVVCTEDRIYLAMEYCPNGELYDWVAREKRLDEKTTCRIMWQLCCAIQY 138 Query: 130 CHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGF-AGTPGYLSPEV 188 H G VHRDLK EN+ L K VKL DFG + + ++ + GT Y +PE+ Sbjct: 139 LHRQGCVHRDLKLENIFL---DKAYNVKLGDFGFSRDSDCSRRTFMNTRCGTVAYCAPEL 195 Query: 189 LKKEPY-GKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQ-IKAGAYDYPSPEWDTVTP 246 ++ Y G+ VDIW+ G+I+Y LL+G PF DED L Q I YP +T++ Sbjct: 196 VQGHKYIGECVDIWSLGIIMYALLIGRLPF-DEDDVSLTEQKIINECPQYP----ETLSK 250 Query: 247 EAKSLINQMLTVNPSKRITASEALKHPW 274 + SL+ +L + R + + + HP+ Sbjct: 251 NSSSLLKSLLCKDYRLRPSIDQIISHPY 278 >SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1023 Score = 115 bits (277), Expect = 1e-26 Identities = 91/300 (30%), Positives = 147/300 (49%), Gaps = 36/300 (12%) Query: 6 RESVSTRFSDNYELKEELGKGAFSIVR---------RAVQKSTGYEFAAKIINTKKLSAR 56 R+S +Y L +G G F V+ + +ST + KI+ + K + + Sbjct: 481 RKSTKNYTFGSYILGRTIGTGEFGKVKLGWPLPKANSTIHRSTP-QVVIKIVLSTKQNCQ 539 Query: 57 DFQKLEREARICRKL--QHPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEA 114 +L RE I + L HP+IV+ D ++ +H +V D V GGELF+ I+AR ++ Sbjct: 540 T-SRLMREVAILKGLGNNHPHIVKYLDFVKTKHHFGIVLDYVNGGELFDYILARRRLEDS 598 Query: 115 DASHCIQQILESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAI--------- 165 A Q++ V + H GVVHRDLK EN+LL + + +ADFG A Sbjct: 599 VACRLFAQLISGVAYLHSRGVVHRDLKLENILLDTNRN---IVIADFGFATTFGHFNTLS 655 Query: 166 --EVQGDQQAWFGFA-GTPGYLSPEVL--KKEPY-GKPVDIWACGVILYILLVGYPPFWD 219 + ++ F + G+P Y +PE++ K Y G DIW+CGVILY +L GY PF D Sbjct: 656 EHSLPTEKPDLFSTSCGSPCYAAPELVNCKSGMYAGTQADIWSCGVILYAMLAGYLPF-D 714 Query: 220 EDQYRLYAQIKAGAYDY----PSPEWDTVTPEAKSLINQMLTVNPSKRITASEALKHPWI 275 +D + + Y Y P + +A+ ++ ++L +P+KR+ S + H ++ Sbjct: 715 DDPHNPNGENVPRLYRYICSTPLIFPEFFKSKARDILKKILVPDPAKRVRMSAIMNHAYL 774 >SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces pombe|chr 1|||Manual Length = 471 Score = 114 bits (274), Expect = 3e-26 Identities = 69/262 (26%), Positives = 132/262 (50%), Gaps = 7/262 (2%) Query: 14 SDNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQH 73 +++Y L +LG G+F +V +A + +G A K I+ + D +E+E + Sbjct: 6 ANSYTLLRKLGSGSFGVVWKARENVSGDIIAIKQIDLET-GIDDITDIEQEVFMLSNCNS 64 Query: 74 PNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHN 133 N+++ + + + +++ + + GG + ++ +E S ++++L +++ H Sbjct: 65 SNVIQYYGCFVDGYTLWILMEHMDGGSV-SGLLKMGRLNEQVISIILREVLYGLNYLHGQ 123 Query: 134 GVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEP 193 +HRD+K N+LL+S VKLADFG+A ++ F GTP +++PEV+++ Sbjct: 124 NKIHRDIKAANILLSSSTGN--VKLADFGVAAQLSNAASRRHTFVGTPFWMAPEVIQQTS 181 Query: 194 YGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDTVTPEAKSLIN 253 YG DIW+ G+ + G PP R+ +I P D +P + ++ Sbjct: 182 YGLAADIWSLGITAIEMANGIPPRATMHPMRVIFEIPQSE---PPKLDDHFSPTFRDFVS 238 Query: 254 QMLTVNPSKRITASEALKHPWI 275 L +NP+ R +A E L+HP+I Sbjct: 239 CCLDLNPNMRWSAKELLQHPFI 260 >SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 372 Score = 113 bits (271), Expect = 7e-26 Identities = 104/320 (32%), Positives = 157/320 (49%), Gaps = 53/320 (16%) Query: 3 NPNRESVSTRFSD-----NYELKEE------LGKGAFSIVRRAVQKSTGYEFAAKIINTK 51 N N+ESV+T S N+EL EE +G+GA+ +V A+ K +G + A K I+ Sbjct: 14 NSNKESVATSRSPHTHDLNFELPEEYEMINLIGQGAYGVVCAALHKPSGLKVAVKKIHPF 73 Query: 52 KLSARDFQKLEREARICRKLQHPNIVRLHD-----SIQEEHCHYLVFDLVTGGELFEDIV 106 + L RE ++ R +H NI+ + D S QE Y+V +L+ +L+ ++ Sbjct: 74 NHPVFCLRTL-REIKLLRHFRHENIISILDILPPPSYQELEDVYIVQELMET-DLYR-VI 130 Query: 107 AREFYSEADASHCIQQILESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLA-- 164 + S+ + QIL ++ H GVVHRDLKP NLLL + +K+ADFGLA Sbjct: 131 RSQPLSDDHCQYFTYQILRALKAMHSAGVVHRDLKPSNLLLNANCD---LKVADFGLARS 187 Query: 165 IEVQGDQQAWF-GFAGTPGYLSPEV-LKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQ 222 QG + + T Y +PE+ L Y K +D+W+ G IL +L P F +D Sbjct: 188 TTAQGGNPGFMTEYVATRWYRAPEIMLSFREYSKAIDLWSTGCILAEMLSARPLFPGKDY 247 Query: 223 YRL---------------YAQIK-AGAYDY-------PSPEWDTVTPEAK----SLINQM 255 + +++IK A A Y P + + P+A L+ ++ Sbjct: 248 HSQITLILNILGTPTMDDFSRIKSARARKYIKSLPFTPKVSFKALFPQASPDAIDLLEKL 307 Query: 256 LTVNPSKRITASEALKHPWI 275 LT NP KRITA EALKHP++ Sbjct: 308 LTFNPDKRITAEEALKHPYV 327 >SPCC1322.08 |srk1|mkp1|MAPK-activated protein kinase Srk1|Schizosaccharomyces pombe|chr 3|||Manual Length = 580 Score = 111 bits (268), Expect = 2e-25 Identities = 52/120 (43%), Positives = 74/120 (61%), Gaps = 2/120 (1%) Query: 156 VKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEPYGKPVDIWACGVILYILLVGYP 215 ++LADFGL+ +V D GT GY +PE+++ E Y K VD+WA G +LY +L G+P Sbjct: 304 IRLADFGLS-KVVWDSHTQTP-CGTMGYTAPEIVRDERYSKGVDMWALGCVLYTILCGFP 361 Query: 216 PFWDEDQYRLYAQIKAGAYDYPSPEWDTVTPEAKSLINQMLTVNPSKRITASEALKHPWI 275 PF+DE L ++ G Y + SP WD ++ AK LI+ +LTV+P R + L HPWI Sbjct: 362 PFYDESISLLTKKVSRGEYSFLSPWWDDISKSAKDLISHLLTVDPESRYDIHQFLAHPWI 421 Score = 105 bits (253), Expect = 1e-23 Identities = 58/146 (39%), Positives = 87/146 (59%), Gaps = 11/146 (7%) Query: 15 DNYELKEELGKGAFSIVRRAVQKSTGYEFAAKII-----NTKKLSARDFQKLE-----RE 64 + Y L +++G GAFS V +A+ TG + A K++ NT R Q +E +E Sbjct: 122 EQYTLLQKMGDGAFSNVYKAIHNRTGEKVAIKVVQRAQPNTDPRDPRKRQGVESHNILKE 181 Query: 65 ARICRKLQHPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQIL 124 +I R+++HPNI++L + IQ +YLV +L GGELF IV ++SE + H I Q+ Sbjct: 182 VQIMRRVKHPNIIQLLEFIQTPEYYYLVLELADGGELFHQIVRLTYFSEDLSRHVITQVA 241 Query: 125 ESVHHCHHN-GVVHRDLKPENLLLAS 149 ++ + H + GVVHRD+KPENLL S Sbjct: 242 HAIRYLHEDCGVVHRDIKPENLLFDS 267 >SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosaccharomyces pombe|chr 1|||Manual Length = 636 Score = 111 bits (267), Expect = 2e-25 Identities = 84/287 (29%), Positives = 140/287 (48%), Gaps = 25/287 (8%) Query: 9 VSTRFSDNY-ELKEELGKGAFSIVRRAVQ---KSTGYE--FAAKIINTKKLSARD--FQK 60 VS F + Y +E +G+GAF +VR A + +++G E +A K K ++ ++ Sbjct: 342 VSASFVEKYGRCQEVIGRGAFGVVRIAHKVDPQNSGSETLYAVKEFRRKPAESQKKYTKR 401 Query: 61 LEREARICRKLQHPNIVRLHDSIQEEHCHYL-VFDLVTGGELFEDIVAREFYSEADASHC 119 L E I L+HPN++ D IQ+ Y V +L +GG+L+ I+A +A Sbjct: 402 LTSEFCISSSLRHPNVIHTLDLIQDGKGDYCEVMELCSGGDLYTLIMAAGRLEPMEADCF 461 Query: 120 IQQILESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADF--GLAIEVQGDQQAWF-- 175 +Q++ V + H GV HRDLKPENLLL ++K+ DF G + +++A Sbjct: 462 FKQLMRGVDYLHDMGVAHRDLKPENLLL---TVSGSLKITDFGNGECFRMAWEKEAHMTC 518 Query: 176 GFAGTPGYLSPEVLKKEPYG-KPVDIWACGVILYILLVGYPPFW------DEDQYRLYAQ 228 G G+ Y++PE + + + VD+WACGVI + G W +++ Y Y Sbjct: 519 GLCGSAPYIAPEEYTESEFDPRAVDVWACGVIYMAMRTG-RHLWRVAKKSEDEYYSRYLM 577 Query: 229 IKAGAYDYPSPEWDTVTPEAKSLINQMLTVNPSKRITASEALKHPWI 275 + Y E ++ + +L NP+ R+TA + +K W+ Sbjct: 578 DRKNESGYEPIEM-LERSRCRNTLYNILHPNPTYRLTAKQIMKSEWV 623 >SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosaccharomyces pombe|chr 2|||Manual Length = 652 Score = 110 bits (265), Expect = 4e-25 Identities = 85/318 (26%), Positives = 143/318 (44%), Gaps = 14/318 (4%) Query: 14 SDNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIIN--TKKLSARDFQKLEREARICRKL 71 S Y E +G+G++ V R + T A KI+N T + D QK ++ Sbjct: 7 SSPYTKLELVGRGSYGAVYRGICNLTKETVAIKILNLDTDEDEVSDIQKEVAVLSELKQS 66 Query: 72 QHPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCH 131 NI++ H S +++ D GG + ++ SE S +++ L+++ H Sbjct: 67 DVENIIKYHGSYLVGTNLWIIMDYCHGGSV-RTLMEAGPISEPCISLILRETLQALKFIH 125 Query: 132 HNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKK 191 H G++HRD+K N+L++ VKL DFG+A E+ +++ F GTP +++PEV++ Sbjct: 126 HAGIIHRDIKAANILVSMSGN---VKLCDFGVAAELNINRRKRITFIGTPYWMAPEVIRD 182 Query: 192 -EPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDTVTPEAKS 250 + Y DIW+ G+ Y + G PP ED +R I A+ P + K Sbjct: 183 GQEYNVMADIWSLGITAYEIATGSPPHAKEDPFRAVYLI---AHTAPPRLNGNFSALLKE 239 Query: 251 LINQMLTVNPSKRITASEALKHPWICHRERVASVMHRQETVDCLKKFNARRKLKGAILTT 310 I L P +R+ +SE LK +I R M E + +K+++ + G T Sbjct: 240 FIASCLQDVPQRRLDSSELLKSKFIKQYSR----MSISELTNVVKRYDTWQAAGGIPQTL 295 Query: 311 MLATRNFSGKSMVNKKGD 328 +L G + D Sbjct: 296 LLGEEADDGSDPDQETSD 313 >SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|Schizosaccharomyces pombe|chr 3|||Manual Length = 288 Score = 107 bits (256), Expect = 5e-24 Identities = 86/287 (29%), Positives = 136/287 (47%), Gaps = 32/287 (11%) Query: 16 NYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQHPN 75 NY+ E+LG+G ++ V + + TG A K+I + RE + ++L+HPN Sbjct: 2 NYQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRIDADEGTPSTAI-REISLMKELRHPN 60 Query: 76 IVRLHDSIQEEHCHYLVFDLVTGG-ELFEDIVARE-FYSEADASHCIQQILESVHHCHHN 133 I+ L D +Q E+ LVF+ + + + D + + + QQ+L+ + CH N Sbjct: 61 IMSLSDVLQTENKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCHEN 120 Query: 134 GVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEV-LKKE 192 V+HRDLKP+NLL+ S+ + +KLADFGLA + + T Y +P+V L Sbjct: 121 RVLHRDLKPQNLLINSRGE---LKLADFGLARSIGIPVNTFSNEVVTLWYRAPDVLLGSR 177 Query: 193 PYGKPVDIWACGVILYILLVGYPPFW---DEDQ----YRLYAQIKAGAYDYPS--PEW-- 241 Y +DIW+ G I+ + G P F +EDQ +RL ++ S PE+ Sbjct: 178 VYSTSIDIWSVGCIMAEMATGRPLFAGSNNEDQLLKIFRLLGTPTEQSWPGISLLPEYKP 237 Query: 242 --------------DTVTPEAKSLINQMLTVNPSKRITASEALKHPW 274 T P L+ +ML + P R T +AL+H W Sbjct: 238 TFPIYKAQDLAYLFPTFDPLGLDLLRRMLRLQPELRTTGQDALQHAW 284 >SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schizosaccharomyces pombe|chr 2|||Manual Length = 398 Score = 102 bits (245), Expect = 1e-22 Identities = 91/297 (30%), Positives = 142/297 (47%), Gaps = 35/297 (11%) Query: 15 DNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQHP 74 D+YE+ E++ +G++ IV R + KST A K I RE ++H Sbjct: 72 DDYEILEKIEEGSYGIVYRGLDKSTNTLVALKKIKFDPNGIGFPITSLREIESLSSIRHD 131 Query: 75 NIVRLHDSIQEEHCH--YLVFDLVTGG-ELFEDIVAREFYSEADASHCIQQILESVHHCH 131 NIV L + + YLV + + + D + +F +++ + Q+L + H Sbjct: 132 NIVELEKVVVGKDLKDVYLVMEFMEHDLKTLLDNMPEDFL-QSEVKTLMLQLLAATAFMH 190 Query: 132 HNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKK 191 H+ +HRDLKP NLL+ + + +KLADFGLA V + + T Y +PE+L Sbjct: 191 HHWYLHRDLKPSNLLMNNTGE---IKLADFGLARPVSEPKSSLTRLVVTLWYRAPELLLG 247 Query: 192 EP-YGKPVDIWACGVI-------------------LYIL--LVGYPPFWDEDQYRL--YA 227 P YGK +D+W+ G I LY + L+GYP + QY L YA Sbjct: 248 APSYGKEIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLLGYPTREEWPQYFLLPYA 307 Query: 228 -QIK---AGAYDYPSPEWDTVTPEAKSLINQMLTVNPSKRITASEALKHPWICHRER 280 +IK + +T A L+N++L++NP+KRI+A EAL+HP+ R Sbjct: 308 NKIKHPTVPTHSKIRTSIPNLTGNAYDLLNRLLSLNPAKRISAKEALEHPYFYESPR 364 >SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces pombe|chr 1|||Manual Length = 312 Score = 101 bits (242), Expect = 2e-22 Identities = 67/253 (26%), Positives = 118/253 (46%), Gaps = 6/253 (2%) Query: 23 LGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDS 82 +G+G+F V RA + A K+++ + + L +E L +I + + S Sbjct: 12 IGQGSFGSVFRAQDVESSKIVALKVVDLDATKDQ-IETLTQEINFLIDLNSVHITKYYAS 70 Query: 83 IQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNGVVHRDLKP 142 + ++ + GG + + +SE + ++Q+LE++ + H G +HRD+K Sbjct: 71 FVDGFRLWITMEYCDGGSCLDLLKLSGTFSERVIAEVMRQVLEALVYLHGQGKMHRDIKA 130 Query: 143 ENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEPYGKPVDIWA 202 N+L K VKLADFG++ +++ + F GTP +++PEV+K+ Y DIW+ Sbjct: 131 ANILTM---KDGLVKLADFGVSGQLESLRDKNDDFVGTPFWMAPEVVKQTGYNYKADIWS 187 Query: 203 CGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDTVTPEAKSLINQMLTVNPSK 262 G+ Y L G PP+ ++ I + PS E + ++ L NP Sbjct: 188 LGITAYELATGEPPYSGIHPMKVLLLIP--KHSPPSLERSKFSRAFCDFVSNCLKKNPKD 245 Query: 263 RITASEALKHPWI 275 R TA KH +I Sbjct: 246 RATAEYLSKHKFI 258 >SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase Ppk6|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 98.7 bits (235), Expect = 2e-21 Identities = 82/271 (30%), Positives = 136/271 (50%), Gaps = 27/271 (9%) Query: 16 NYELKEELGKGAFSIVRRAVQKSTG-YEFAAKIINTKKLSA------RDFQKLEREARIC 68 +Y +ELG GA+ V+ A KS +E K I+ ++ +D + E I Sbjct: 502 SYTTIKELGIGAYGQVKLATYKSNKVHEVILKSISKSRILLDSWMRDKDLGTVPMEISIL 561 Query: 69 RKLQ---HPNIVRLHDSIQEEHCHYLVFDLVTGG-ELFEDIVAREFYSEADASHCIQQIL 124 L+ HPNIV++ ++ +YL+ + G +LF+ I + SE ++ QI Sbjct: 562 HFLKAHSHPNIVKMITFFEDNENYYLLTEPQKPGIDLFDYIELKPSISEKESKAIFFQIA 621 Query: 125 ESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYL 184 +V H H ++HRD+K EN++L + G A +L DFG + + + F GT G+ Sbjct: 622 LAVAHLHSFDIIHRDIKDENVIL--EGNGCA-RLIDFGSSSLTKNG--PFDTFRGTVGFA 676 Query: 185 SPEVLKKEPY-GKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDT 243 +PE+L+ E Y GK DIWA G++LY ++ P+++ ++ L A+++ ++ D Sbjct: 677 APELLRGEKYLGKEQDIWALGILLYTIVYRENPYYNIEEI-LDAKLRI-PFELSKDNVD- 733 Query: 244 VTPEAKSLINQMLTVNPSKRITASEALKHPW 274 LI +ML N RIT E L+H W Sbjct: 734 -------LICRMLDRNVHDRITIEETLQHHW 757 >SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizosaccharomyces pombe|chr 1|||Manual Length = 1401 Score = 98.3 bits (234), Expect = 2e-21 Identities = 75/268 (27%), Positives = 119/268 (44%), Gaps = 25/268 (9%) Query: 26 GAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQ----KLEREARICRKLQHPNIVRLHD 81 G F V V TG A K I K +R F+ ++ E + +L HPN+V + Sbjct: 1046 GMFGDVYTGVNMETGDLLAVKEI--KLQDSRTFRSTVDQIHNEMTVLERLNHPNVVTYYG 1103 Query: 82 SIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNGVVHRDLK 141 Y+ + GG L + + E + Q+LE + + H ++HRD+K Sbjct: 1104 VEVHREKVYIFMEFCQGGSLADLLAHGRIEDENVLKVYVVQLLEGLAYIHSQHILHRDIK 1163 Query: 142 PENLLLASKAKGAAVKLADFGLAIEV----------QGDQQAWFGFAGTPGYLSPEVL-- 189 P N+LL + +K +DFG A+ V + Q AGTP Y++PE++ Sbjct: 1164 PANILLDHR---GMIKYSDFGSALYVSPPTDPEVRYEDIQPELQHLAGTPMYMAPEIILG 1220 Query: 190 -KKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPS-PEWDTVTPE 247 KK +G +DIW+ G ++ ++ G P W E A PS P+ + ++ Sbjct: 1221 TKKGDFG-AMDIWSLGCVILEMMTGSTP-WSEMDNEWAIMYHVAAMHTPSIPQNEKISSL 1278 Query: 248 AKSLINQMLTVNPSKRITASEALKHPWI 275 A+ I Q +P +R A + L HPWI Sbjct: 1279 ARDFIEQCFERDPEQRPRAVDLLTHPWI 1306 >SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccharomyces pombe|chr 2|||Manual Length = 605 Score = 96.7 bits (230), Expect = 7e-21 Identities = 75/267 (28%), Positives = 125/267 (46%), Gaps = 23/267 (8%) Query: 21 EELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLH 80 EELGKG + +V +A+ + TG A K I L F ++ E I K P IV + Sbjct: 324 EELGKGNYGVVYKALHQPTGVTMALKEIRLS-LEEATFNQIIMELDILHKAVSPYIVDFY 382 Query: 81 DSIQEEHCHYLVFDLVTGGELFEDIVAREFYSE---ADASHCIQQILESVHHCHHNGVVH 137 + E ++ + + G + + + A E A ++ + Q L+++ H+ ++H Sbjct: 383 GAFFVEGSVFICMEYMDAGSM-DKLYAGGIKDEGVLARTAYAVVQGLKTLKEEHN--IIH 439 Query: 138 RDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFA--GTPGYLSPEVLKKE--- 192 RD+KP N+L+ S + VKL DFG V G+ A G Y++PE ++ Sbjct: 440 RDVKPTNVLVNSNGQ---VKLCDFG----VSGNLVASISKTNIGCQSYMAPERIRVGGPT 492 Query: 193 ----PYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDTVTPEA 248 Y D+W+ G+ + + +G P+ E ++AQ+ A P D+ +PEA Sbjct: 493 NGVLTYTVQADVWSLGLTILEMALGAYPYPPESYTSIFAQLSAICDGDPPSLPDSFSPEA 552 Query: 249 KSLINQMLTVNPSKRITASEALKHPWI 275 + +N+ L NPS R E HPW+ Sbjct: 553 RDFVNKCLNKNPSLRPDYHELANHPWL 579 >SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 96.7 bits (230), Expect = 7e-21 Identities = 64/208 (30%), Positives = 104/208 (50%), Gaps = 5/208 (2%) Query: 17 YELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQHPNI 76 YE +++G+G + V +A+ TG A K I ++ RE +I ++L+H NI Sbjct: 277 YEKIDQIGEGTYGKVYKAINTVTGDLVALKRIRLEQEKDGFPITTVREVKILQRLRHKNI 336 Query: 77 VRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNGVV 136 VRL + + E+ Y+VF+ + + ++ ++ + H +QI E++ + HH GV+ Sbjct: 337 VRLLEIMVEKSSVYMVFEYMDHDLTGVLLNSQLHFTPGNIKHLSKQIFEALAYLHHRGVL 396 Query: 137 HRDLKPENLLLASKAKGAAVKLADFGLA-IEVQGDQQAWFGFAGTPGYLSPEVLKKE-PY 194 HRD+K N+LL + +K ADFGLA + T + PE+L E Y Sbjct: 397 HRDIKGSNILLNNNGD---LKFADFGLARFNTSSKSANYTNRVITLWFRPPELLLGETAY 453 Query: 195 GKPVDIWACGVILYILLVGYPPFWDEDQ 222 VDIW+ G I+ L G P F D+ Sbjct: 454 DTAVDIWSAGCIVMELFTGKPFFQGRDE 481 >SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2|Schizosaccharomyces pombe|chr 2|||Manual Length = 659 Score = 94.7 bits (225), Expect = 3e-20 Identities = 68/267 (25%), Positives = 133/267 (49%), Gaps = 22/267 (8%) Query: 23 LGKGAFSIVRRAVQKSTGYEFAAK------IINTKKLSARDFQKLEREARICRKLQHPNI 76 +G G+F V + S+G A K + +K A+ L E + ++L H +I Sbjct: 400 IGSGSFGQVYLGMNASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQELSHEHI 459 Query: 77 VR-LHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNGV 135 V+ L ++ +H + + + V GG + + + E + I+Q L+ + + H G+ Sbjct: 460 VQYLGSNLNSDHLN-IFLEYVPGGSVAGLLTMYGSFEETLVKNFIKQTLKGLEYLHSRGI 518 Query: 136 VHRDLKPENLLLASKAKGAAVKLADFGLA--IEVQGDQQAWFG----FAGTPGYLSPEVL 189 VHRD+K N+L+ +K K +K++DFG++ +E+ G F G+ +++PEV+ Sbjct: 519 VHRDIKGANILVDNKGK---IKISDFGISKKLELNSTSTKTGGARPSFQGSSFWMAPEVV 575 Query: 190 KKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAY-DYPSPEWDTVTPEA 248 K+ + + DIW+ G ++ +L P+ + DQ + +I ++PS ++ A Sbjct: 576 KQTMHTEKTDIWSLGCLVIEMLTSKHPYPNCDQMQAIFRIGENILPEFPS----NISSSA 631 Query: 249 KSLINQMLTVNPSKRITASEALKHPWI 275 + + ++ + R TASE L HP++ Sbjct: 632 IDFLEKTFAIDCNLRPTASELLSHPFV 658 >SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyces pombe|chr 1|||Manual Length = 349 Score = 93.5 bits (222), Expect = 6e-20 Identities = 70/223 (31%), Positives = 111/223 (49%), Gaps = 14/223 (6%) Query: 9 VSTRFSDNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARIC 68 ++TR+SD + +G GAF +V A + TG A K I + ++ RE ++ Sbjct: 16 ITTRYSD----LQPIGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAKRTYRELKLL 71 Query: 69 RKLQHPNIVRLHDS-IQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESV 127 + L+H NI+ L D I Y V +L+ G +L + +R ++ + + QIL + Sbjct: 72 KHLRHENIISLSDIFISPFEDIYFVTELL-GTDLHRLLTSRPLETQF-IQYFLYQILRGL 129 Query: 128 HHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPE 187 H GV+HRDLKP N+L+ + +K+ DFGLA +Q Q G+ T Y +PE Sbjct: 130 KFVHSAGVIHRDLKPSNILI---NENCDLKICDFGLA-RIQDPQMT--GYVSTRYYRAPE 183 Query: 188 V-LKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQI 229 + L + Y VDIW+ G I ++ G P F D ++ I Sbjct: 184 IMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGRDHVNQFSII 226 Score = 32.7 bits (71), Expect = 0.12 Identities = 13/30 (43%), Positives = 22/30 (73%) Query: 246 PEAKSLINQMLTVNPSKRITASEALKHPWI 275 P+A L+ +ML +P KRI+A++AL H ++ Sbjct: 270 PDAIDLLEKMLVFDPRKRISAADALAHNYL 299 >SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosaccharomyces pombe|chr 1|||Manual Length = 650 Score = 93.1 bits (221), Expect = 8e-20 Identities = 65/218 (29%), Positives = 111/218 (50%), Gaps = 10/218 (4%) Query: 17 YELKEELGKGAFSIVRRAVQKSTGYEFAA-KIINTKKLSARDFQKLEREARICRKLQHPN 75 Y + ++G G F V A K+ E A K + K D +L + R ++ N Sbjct: 36 YNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREVHSLLRLSENEN 95 Query: 76 IVRLHDS-IQEEHCHYLVFDLVTGGELFEDIVAREF--YSEADASHCIQQILESVHHCHH 132 IV + D I + C ++V + + L++ I R+ + ++QI + ++H H Sbjct: 96 IVNIFDLYIDQFRCLHIVMEFLDCN-LYQLISTRKNDPLTLEQVQDIMRQIFKGLNHIHT 154 Query: 133 NGVVHRDLKPENLLLASKAKGAA--VKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLK 190 NG HRD+KPEN+L++S + ++ VK+ADFGLA E+ + + + T Y +PE+L Sbjct: 155 NGFFHRDMKPENILISSNSDSSSFNVKIADFGLAREI-NSRPPYTEYVSTRWYRAPELLL 213 Query: 191 KEP-YGKPVDIWACGVILYILLVGYPPFWDEDQY-RLY 226 ++ Y PVDI+A G + + + P F D + +LY Sbjct: 214 RDSYYSFPVDIYAAGCMAFEIATLQPIFPGNDDFDQLY 251 >SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1|||Manual Length = 1116 Score = 92.3 bits (219), Expect = 1e-19 Identities = 77/276 (27%), Positives = 124/276 (44%), Gaps = 22/276 (7%) Query: 21 EELGKGAFSIVRRAVQKSTGYEFAAKIINTKK-LSARDFQ-------KLEREARICRKLQ 72 E +G G + V A+ +TG A K + + ++ R Q + E + L Sbjct: 829 ELIGNGTYGKVFLAMNINTGELIAVKQVEIPQTINGRHDQLRKDIVDSINAEISMIADLD 888 Query: 73 HPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHH 132 H NIV+ + E + + V+GG + + + E +Q+L + + H Sbjct: 889 HLNIVQYLGFEKTETDISIFLEYVSGGSIGRCLRNYGPFEEQLVRFVSRQVLYGLSYLHS 948 Query: 133 NGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQG--DQQAWFGFAGTPGYLSPEVLK 190 G++HRDLK +NLL+ K++DFG++ D A G+ +++PEV+ Sbjct: 949 KGIIHRDLKADNLLIDF---DGVCKISDFGISKHSDNVYDNDANLSMQGSIFWMAPEVIH 1005 Query: 191 K--EPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAG----AYDYPSPEWDTV 244 + Y VD+W+ G ++ +L G P W D+ + A K G A PS V Sbjct: 1006 NDHQGYSAKVDVWSLGCVVLEMLAGRRP-WSTDE-AIQAMFKLGTEKKAPPIPSELVSQV 1063 Query: 245 TPEAKSLINQMLTVNPSKRITASEALKHPWI-CHRE 279 +PEA +N TVN R TA E L HP++ C E Sbjct: 1064 SPEAIQFLNACFTVNADVRPTAEELLNHPFMKCDEE 1099 >SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 474 Score = 91.5 bits (217), Expect = 3e-19 Identities = 79/293 (26%), Positives = 145/293 (49%), Gaps = 27/293 (9%) Query: 17 YELKEELGKGAFSIVRRA-----VQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKL 71 Y+++ L KG++ V A + ++A K I KK + Q++ ++ R Sbjct: 9 YKVERPLNKGSYGTVVLAHRLFRTPRCKDLKYAIKCI--KKPAYTFLQEVNILRQLSRS- 65 Query: 72 QHPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQ----QILESV 127 +H NI+ +S ++ +Y+V + G+L+E I+ +F + + I+ QI++ V Sbjct: 66 RHRNIIHFVESFEDNVYYYVVLEYCPLGDLYECILNNDFPNAKNQPEMIKNIFLQIIDGV 125 Query: 128 HHCHHNGVVHRDLKPENLLLASKAKGA--AVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 185 H H +G+ HRDLKPEN LL+ G+ VK++DFGLA D+ ++ G+ Y++ Sbjct: 126 AHLHSHGIYHRDLKPENFLLSLSEDGSELVVKISDFGLACR---DKISYDFGTGSDRYMA 182 Query: 186 PEVLKK-EPYG---KPVDIWACGVILYILLVGYPPF-WDEDQYRLYAQIKAGAYDYPSPE 240 PE ++ + G + DIWA G+ L L+ PF + ++ ++A A Sbjct: 183 PEQFEEVDGAGYSPRAADIWALGICLLNLIFARNPFTYPHEKDPIFADYMLDAMTL-FDV 241 Query: 241 WDTVTPEAKSLINQMLTVNPSKRITAS--EAL--KHPWICHRERVASVMHRQE 289 + T++ + +++ L V+P KR A EA+ W E + S ++ +E Sbjct: 242 FPTLSQDTYNVLRACLCVSPEKRSLAKTREAVLAVTKWTTDDEELESFVNEEE 294 >SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase kinase Win1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1436 Score = 91.1 bits (216), Expect = 3e-19 Identities = 71/282 (25%), Positives = 124/282 (43%), Gaps = 30/282 (10%) Query: 23 LGKGAFSIVRRAVQKSTGYEFAAK--IINTKKLSARDFQKLEREARICRKLQHPNIVRLH 80 +G G+F V RAV TG A K ++ ++S ++++ E + HPN+V + Sbjct: 1126 IGSGSFGTVYRAVNLDTGDLMAVKEVALHKPRISRPMIKRIKGEMLVLELFDHPNVVSYY 1185 Query: 81 DSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNGVVHRDL 140 + +L G LFE + E + Q+LE + + H GV H+D+ Sbjct: 1186 GIEVHREKVNIFMELCQGSSLFEFLRYGRIEDELVIQVYVLQLLEGLAYIHSCGVSHQDV 1245 Query: 141 KPENLLL------------ASKAKGAA-VKLADFGLAIEVQG-----------DQQAWFG 176 KPEN+L ++K G+A K+ + E + DQ + Sbjct: 1246 KPENILFDHNGIMKFTDFGSAKMSGSASTKIFEQLTQQEEEEFEKDSEFLQHLDQNRGYS 1305 Query: 177 FAGTPGYLSPEVLKKEPYGK--PVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAY 234 GTP Y++PE++ P + +DIW+ G ++ + G PP W A+ Sbjct: 1306 LTGTPTYMAPELILGNPSERVGAMDIWSLGCVIVEMATGSPP-WPRLDNHFSLMYHIAAH 1364 Query: 235 DYP-SPEWDTVTPEAKSLINQMLTVNPSKRITASEALKHPWI 275 + P P D ++P ++ + + +P++R TA+E L PW+ Sbjct: 1365 NPPIIPADDQLSPLGQNFLKRCFVSDPNQRATAAELLMDPWV 1406 >SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Ppk34|Schizosaccharomyces pombe|chr 3|||Manual Length = 354 Score = 90.6 bits (215), Expect = 4e-19 Identities = 63/225 (28%), Positives = 110/225 (48%), Gaps = 15/225 (6%) Query: 61 LEREARICRKLQHPNIVRLHDSIQEEHCHYL--VFDLVTGGEL--FEDIVAREFYSEADA 116 + +E + + L H N+V+L+ I ++ L V + GG+L + ++ + Sbjct: 118 IRKELDVLKVLDHENVVKLYQVINSDYKDSLCMVLNYCPGGKLASVDHGISFDPMPLETC 177 Query: 117 SHCIQQILESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFG 176 +Q++ +V++ H GV+HRD+KP+N+L + DFGLA + D Sbjct: 178 RKSFRQLVLAVNYIHGKGVIHRDIKPDNILFKENNNLCVI---DFGLAEFLPKDGFV-KP 233 Query: 177 FAGTPGYLSPEVLK---KEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGA 233 +GTP +++PE+ K+ GKP+DIW+ GV LY++ PF + IK + Sbjct: 234 ASGTPAFMAPELFDNELKKIKGKPLDIWSMGVTLYVIAFAEFPFNGSTILDMINVIKGKS 293 Query: 234 YDYPSPEWDTVTPEAKSLINQMLTVNPSKRITASEALKHPWICHR 278 P+ + + L+ + L NP KRIT E L+ P++ R Sbjct: 294 LMIPA----YCNSDLRKLLERCLEKNPEKRITIEELLRDPFLTER 334 Score = 31.9 bits (69), Expect = 0.22 Identities = 21/51 (41%), Positives = 25/51 (49%), Gaps = 3/51 (5%) Query: 17 YELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARD---FQKLERE 64 Y LK LG GA S V AV ST E+A K L R+ +LE+E Sbjct: 40 YRLKNMLGYGACSTVYLAVDVSTNIEYAIKEFKKTSLRRREKFRLMQLEKE 90 >SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schizosaccharomyces pombe|chr 2|||Manual Length = 470 Score = 88.6 bits (210), Expect = 2e-18 Identities = 84/284 (29%), Positives = 127/284 (44%), Gaps = 39/284 (13%) Query: 15 DNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARI-CRKLQH 73 D+ +G GA+ +V +A G +A K + L+ + + RE + R H Sbjct: 16 DSLRFVSIIGAGAYGVVYKAEDIYDGTLYAVKALCKDGLNEKQKKLQARELALHARVSSH 75 Query: 74 PNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQ----QILESVHH 129 P I+ LH ++ E Y+V G+LF I ++ Y SH I+ Q++ +V H Sbjct: 76 PYIITLHRVLETEDAIYVVLQYCPNGDLFTYITEKKVYQ--GNSHLIKTVFLQLISAVEH 133 Query: 130 CHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEV- 188 CH G+ HRDLKPEN+++ + V LADFGLA + FG G+ Y+SPE Sbjct: 134 CHSVGIYHRDLKPENIMVGNDVN--TVYLADFGLA--TTEPYSSDFG-CGSLFYMSPECQ 188 Query: 189 --LKK------------EPYGK--------PVDIWACGVILYILLVGYPPFWDEDQYRLY 226 +KK EP P D+WA G+IL L P W + Sbjct: 189 REVKKLSSLSDMLPVTPEPIESQSSSFATAPNDVWALGIILINLCCKRNP-WKRACSQTD 247 Query: 227 AQIKAGAYDYPSPEWD--TVTPEAKSLINQMLTVNPSKRITASE 268 ++ ++ PS ++ E SL+N++ NP RIT E Sbjct: 248 GTYRSYVHN-PSTLLSILPISRELNSLLNRIFDRNPKTRITLPE 290 >SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosaccharomyces pombe|chr 1|||Manual Length = 722 Score = 88.6 bits (210), Expect = 2e-18 Identities = 77/309 (24%), Positives = 137/309 (44%), Gaps = 34/309 (11%) Query: 15 DNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQHP 74 + Y++ E +G G+F + + + G A K I+ ++ ++ Q + E I R L+HP Sbjct: 2 EKYKILECIGHGSFGRIYKVQRLKDGALLAQKEIHFGNITRQEKQYIADEVNILRNLKHP 61 Query: 75 NIVRL--HDSIQEEHCHYLVFDLVTGGELFEDIVA----REFYSEADASHCIQQILESVH 128 NIV+ + + L + G+L I ++ ++E + Q+L +++ Sbjct: 62 NIVQYCGEELNRSAQVINLYMEYCGHGDLANLIQRYKEEKKRFTEQEVLKFFTQLLLALY 121 Query: 129 HCHHN-------------------GVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQG 169 CH+ V+HRD+KP N+ L + +VKL DFGL+ + Sbjct: 122 RCHYGENAPACDSQWPREIFHPKQSVLHRDIKPANIFLD---ENNSVKLGDFGLSKLLDN 178 Query: 170 DQQAWFGFAGTPGYLSPEVLKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQI 229 + + GTP Y+SPE+++ PY D+WA G +++ + + PF + R Y ++ Sbjct: 179 TRVFTQSYVGTPYYMSPEIIRSSPYSAKSDVWALGCVIFEICMLTHPF----EGRSYLEL 234 Query: 230 KAGAYDYPSPEWD-TVTPEAKSLINQMLTVNPSKRITASEALKHPWICH-RERVASVMHR 287 + WD + + LI L VN R T + L+ P + R ++ S Sbjct: 235 QRNICQGNLSCWDHHYSDDVFLLIRHCLEVNSDLRPTTYQLLRSPILSDIRSKLESERVV 294 Query: 288 QETVDCLKK 296 E D L K Sbjct: 295 LEQSDLLHK 303 >SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schizosaccharomyces pombe|chr 2|||Manual Length = 526 Score = 86.6 bits (205), Expect = 7e-18 Identities = 78/297 (26%), Positives = 130/297 (43%), Gaps = 38/297 (12%) Query: 16 NYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARD-FQKLEREARICRKLQHP 74 ++E LG+G V QKS FA KI+N +++ R ++ E I K +HP Sbjct: 154 SFEKIRLLGQGDVGKVYLVRQKSNHRLFAMKILNKREMIKRHKVNRVLAEQEILTKSKHP 213 Query: 75 NIVRLHDSIQEEHCHYLVFDLVTGGELFEDI--VAREFYSEADASHCIQQILESVHHCHH 132 IV L+ S Q YL + GGE F + + + E DA ++ ++ + H Sbjct: 214 FIVTLYHSFQSRDYLYLCMEYCAGGEFFRALHSLPKHILPEKDACFYAAEVTAALEYLHL 273 Query: 133 NGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQ---------------------GDQ 171 G ++RDLKPEN+LL + + L+DF L+ + D Sbjct: 274 MGFIYRDLKPENILL---HQSGHIMLSDFDLSKPISIVTHPTVVLPKHSTFSQEKPALDT 330 Query: 172 QAWFGFAGTPGYLSPE------VLKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRL 225 ++F T ++ E V++ + VD W G+ +Y +L G PF ++++ Sbjct: 331 NSYFSNFRTNSFVGTEEYIAPEVIRSCGHTVAVDWWTLGIFIYEILYGTTPFKGKNRHAT 390 Query: 226 YAQIKAGAYDYPSPEW-DTVTPEAKSLINQMLTVNPSKR----ITASEALKHPWICH 277 ++ I +P V+ KSLI ++L + SKR AS+ +HP+ H Sbjct: 391 FSNILYSDVSFPEYHGAPNVSSTCKSLIRRLLVKDESKRCGSVAGASDIKQHPFFRH 447 >SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizosaccharomyces pombe|chr 1|||Manual Length = 566 Score = 83.8 bits (198), Expect = 5e-17 Identities = 71/273 (26%), Positives = 124/273 (45%), Gaps = 34/273 (12%) Query: 23 LGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLE-REARICRKLQHPNIVRLHD 81 LGKG V +K +G +A K+++ +++ R+ K E I HP IV L+ Sbjct: 201 LGKGDVGRVYLVREKKSGKFYAMKVLSKQEMIKRNKSKRAFAEQHILATSNHPFIVTLYH 260 Query: 82 SIQEEHCHYLVFDLVTGGELFEDIVAR--EFYSEADASHCIQQILESVHHCHHNGVVHRD 139 S Q + YL + GGE F + R SE +A I ++ ++ + H G ++RD Sbjct: 261 SFQSDEYLYLCMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTAALEYLHLMGFIYRD 320 Query: 140 LKPENLLLASKAKGAAVKLADFGLA-----------IEVQGDQQAWFGFA---------- 178 LKPEN+LL + + L+DF L+ I+ + A +A Sbjct: 321 LKPENILL---HESGHIMLSDFDLSKQSNSAGAPTVIQARNAPSAQNAYALDTKSCIADF 377 Query: 179 ------GTPGYLSPEVLKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAG 232 GT Y++PEV+K + VD W G++ Y +L PF +++ ++ I Sbjct: 378 RTNSFVGTEEYIAPEVIKGCGHTSAVDWWTLGILFYEMLYATTPFKGKNRNMTFSNILHK 437 Query: 233 AYDYPS-PEWDTVTPEAKSLINQMLTVNPSKRI 264 +P + +++ K+LI ++L + + R+ Sbjct: 438 DVIFPEYADAPSISSLCKNLIRKLLVKDENDRL 470 >SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizosaccharomyces pombe|chr 1|||Manual Length = 513 Score = 81.8 bits (193), Expect = 2e-16 Identities = 68/270 (25%), Positives = 122/270 (45%), Gaps = 18/270 (6%) Query: 18 ELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTK---KLSARDFQKLEREARICRKLQHP 74 +L +G+GA S +R ++ + AK+ L R + E L+HP Sbjct: 242 KLNNVIGEGASSFIRVINDRNKLPIYVAKVFRPPLDTSLLRRYVRYFIAEYTFASTLRHP 301 Query: 75 NIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNG 134 NI+++ D I + H + + V +LF + + S A Q+L+ V + H G Sbjct: 302 NIIKVLDIIYKRHTILQIIEYVPY-DLFT-FITKGHCSALKADQMFFQLLDGVAYMHSLG 359 Query: 135 VVHRDLKPENLLLASKAKGAAVKLADFGLAI----EVQGDQQAWFGFAGTPGYLSPEVLK 190 + HRD+K +N++L VK+ DFG A + G G+ Y++PEVL Sbjct: 360 IAHRDIKLDNIMLDENLN---VKIIDFGTAFVFHYPFESTTLMSDGVVGSKPYVAPEVLT 416 Query: 191 KEPYG-KPVDIWACGVI-LYILLVGYP---PFWDEDQYRLYAQIKAGAYDYPSPEWDTVT 245 ++PY VD+W+C ++ I L +P P + ++ LY + + S +++ Sbjct: 417 QKPYDPSAVDVWSCAIVYCCIALKRFPWKVPHTSDKRFNLYV-TQRNDPNTKSQLIESLP 475 Query: 246 PEAKSLINQMLTVNPSKRITASEALKHPWI 275 ++ I ML ++ + R + S A W+ Sbjct: 476 MNSRDTIYHMLDIDFNTRCSISGARSTTWM 505 >SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizosaccharomyces pombe|chr 2|||Manual Length = 461 Score = 81.8 bits (193), Expect = 2e-16 Identities = 69/236 (29%), Positives = 113/236 (47%), Gaps = 25/236 (10%) Query: 12 RFSDNYELKEELGKGAFSIVRRAVQKSTGYE----FAAKIINTKKLSARD----FQKLER 63 RF +++ + + KGA S ++ + + +AAK+ K S + R Sbjct: 115 RFRLDFQHLKSIAKGATSTIKVVTHRDKITDAKIYYAAKVYRKTKTSHKKRLNTMVYFLR 174 Query: 64 EARICRKLQHPNIVRLH------DSIQEEHCHY-LVFDLVTGGELFEDIVAREFYSEADA 116 E I KL HPNI+++ S+ + + LV + G+LF+ I + E D Sbjct: 175 EWSIQPKLDHPNILKVICPCVTLTSVFNKSAGFCLVQEYCPQGDLFKQIEEKVLTLE-DK 233 Query: 117 SHCIQQILESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLA--IEVQGDQQA- 173 ++QIL++V + + HRDLKPEN+L+ + +KL DFG + + GD ++ Sbjct: 234 CCYLKQILQAVAYLQSQRIAHRDLKPENILI---GRDGLLKLTDFGTSEIVGNPGDNESI 290 Query: 174 --WFGFAGTPGYLSPEVLKKEPY-GKPVDIWACGVILYILLVGYPPFWDEDQYRLY 226 G G+ YL+PE + Y G D W+CG++L +L GY PF + LY Sbjct: 291 RFVSGAVGSLAYLAPEAFHENEYCGLLADRWSCGILLKVLFTGYFPFKTSVKTDLY 346 >SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosaccharomyces pombe|chr 2|||Manual Length = 559 Score = 81.4 bits (192), Expect = 3e-16 Identities = 66/211 (31%), Positives = 110/211 (52%), Gaps = 18/211 (8%) Query: 13 FSDNYELKEELGKGAFSIVRRAVQKSTG--YEFAA--KIINTKKLSARDFQKLEREARIC 68 F D Y +K++LG G+F V A +K YE A K+ N+ K + RE+ Sbjct: 17 FEDRYLVKQKLGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSKPKPKHELLKLRESLAL 76 Query: 69 RKL-QHPNIVRLHDSIQEEHCH-YLVFDLVTGG--ELFEDIVAREFYSEADASHCIQQIL 124 RK+ +HP ++ L ++ + + + +LV + + +LF+ R F E A + + QI+ Sbjct: 77 RKISKHPCLIDLLETFMDPYRNIFLVMEFMDCNLFQLFKRRQGRLFTKET-AFNILLQII 135 Query: 125 ESVHHCHHNGVVHRDLKPENLL---LASK--AKGAAVKLADFGLA-IEVQGDQQAWFGFA 178 + H H +G +HRD+KPEN+L ++ K + ++KL DFGLA V D + Sbjct: 136 SGIEHIHKHGFMHRDIKPENILVKRISPKPISSRYSIKLGDFGLARPSVSSDPLT--EYV 193 Query: 179 GTPGYLSPE-VLKKEPYGKPVDIWACGVILY 208 T Y +PE +L+ Y VD++A G I++ Sbjct: 194 STRWYRAPELLLRSGSYNHSVDLYAFGCIVF 224 >SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Schizosaccharomyces pombe|chr 2|||Manual Length = 297 Score = 81.4 bits (192), Expect = 3e-16 Identities = 82/295 (27%), Positives = 135/295 (45%), Gaps = 37/295 (12%) Query: 15 DNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQ-- 72 +NY+ E++G+G + +V +A K +G A K I + S RE + +++ Sbjct: 2 ENYQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVNDE 61 Query: 73 --HPNIVRLHDSIQEEHCHYLVFDLVTGG-ELFEDIVAREFYSEAD---ASHCIQQILES 126 N VRL D + E YLVF+ + + + D ++ + D Q++ Sbjct: 62 NNRSNCVRLLDILHAESKLYLVFEFLDMDLKKYMDRISETGATSLDPRLVQKFTYQLVNG 121 Query: 127 VHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSP 186 V+ CH ++HRDLKP+NLL+ K +KLADFGLA + + T Y +P Sbjct: 122 VNFCHSRRIIHRDLKPQNLLI---DKEGNLKLADFGLARSFGVPLRNYTHEIVTLWYRAP 178 Query: 187 EV-LKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQ----YRLY-------AQIKAGA- 233 EV L Y VDIW+ G I ++ P F + + ++++ ++ G Sbjct: 179 EVLLGSRHYSTGVDIWSVGCIFAEMIRRSPLFPGDSEIDEIFKIFQVLGTPNEEVWPGVT 238 Query: 234 --YDYPS--PEW-----DTVTP----EAKSLINQMLTVNPSKRITASEALKHPWI 275 DY S P W V P +A L++ ML +P+ RI+A AL+ ++ Sbjct: 239 LLQDYKSTFPRWKRMDLHKVVPNGEEDAIELLSAMLVYDPAHRISAKRALQQNYL 293 >SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1087 Score = 81.0 bits (191), Expect = 4e-16 Identities = 66/220 (30%), Positives = 108/220 (49%), Gaps = 14/220 (6%) Query: 17 YELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQHPNI 76 YE+ + LGKG+F V R + TG A KII KK R + E +I +K++ + Sbjct: 699 YEVVDFLGKGSFGQVLRCIDYETGKLVALKIIRNKK---RFHMQALVETKILQKIREWDP 755 Query: 77 VRLHDSIQ-EEHC----HYLVFDLVTGGELFEDIVAREFYSEADA--SHCIQQILESVHH 129 + + +Q +H H V + G L+E I + F +Q+++ + Sbjct: 756 LDEYCMVQYTDHFYFRDHLCVATELLGKNLYELIKSNGFKGLPIVVIKSITRQLIQCLTL 815 Query: 130 CHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVL 189 + V+H DLKPEN+LL K + VK+ DFG + +G+ + + + Y SPEV+ Sbjct: 816 LNEKHVIHCDLKPENILLCHPFK-SQVKVIDFGSSC-FEGE--CVYTYIQSRFYRSPEVI 871 Query: 190 KKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQI 229 YG P+D+W+ G I+ + G+P F E++ A I Sbjct: 872 LGMGYGTPIDVWSLGCIIAEMYTGFPLFPGENEQEQLACI 911 >SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyces pombe|chr 3|||Manual Length = 781 Score = 80.6 bits (190), Expect = 5e-16 Identities = 73/254 (28%), Positives = 118/254 (46%), Gaps = 33/254 (12%) Query: 4 PNRESVSTRFSDNYELKEE---LGKGAFSIVRRAVQKST-----GYEFAAKIINTKKLSA 55 P + V R S Y+L +E +G GA +++R K+ FA K K Sbjct: 430 PYAKRVVPRLSAKYKLVDETKDMGSGATAVIRIVTLKNPKENEKNLRFAVKAYRRKADDE 489 Query: 56 RDFQ---KLEREARICRKLQHPNIVRLHDSIQEEHCHYL-------VFDLVTGGELFEDI 105 D Q KL E + +++HPN+V+ +D + H L V D G+L I Sbjct: 490 TDGQYIAKLASEWLVQCRMEHPNVVKSYDLCIDSHIFPLYSDTWCAVMDFCPRGDLLSLI 549 Query: 106 VAR-EFYSEADASHCIQQILESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLA 164 R + + D I+QIL +++ H G+ HRD+KPEN+L+ ++ +++ DFG A Sbjct: 550 EDRHDRLGKKDFECMIKQILRGLNYIHSQGIAHRDIKPENILI---SEYGVLRITDFG-A 605 Query: 165 IEV---QGD-----QQAWFGFAGTPGYLSPEVLKKEPYGK-PVDIWACGVILYILLVGYP 215 +V GD + G G+ Y++PE+L Y D+W+ ++L+ L Sbjct: 606 CDVLCNPGDDITAVESKSMGIFGSDPYMAPEILTPGSYNAFFADMWSTAIVLHCLYFRTY 665 Query: 216 PFWDEDQY-RLYAQ 228 PF Q +LYA+ Sbjct: 666 PFRKASQNDQLYAK 679 >SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 78.6 bits (185), Expect = 2e-15 Identities = 67/229 (29%), Positives = 112/229 (48%), Gaps = 18/229 (7%) Query: 23 LGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSA--RDF-QKLEREARICRKLQHPNIVRL 79 LG GA VR + S G FA K ++ + R++ +K+ E I L H NI+ Sbjct: 308 LGSGAGGSVRIMKRSSDGKIFAVKEFRARRPTETEREYARKVTAEFCIGSALHHTNIIET 367 Query: 80 HDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNGVVHRD 139 D ++E Y V + ++F +++ + + + C +Q+L V + H G+ HRD Sbjct: 368 LDIVEENKKFYEVMEYAPY-DMFSIVMSGKM-TMPEVYCCFKQLLSGVAYLHSMGLAHRD 425 Query: 140 LKPENLLLASKAKGAAVKLADFGLAI----EVQGDQQAWFGFAGTPGYLSPEVLKKEPYG 195 LK +NL++ S VK+ DFG A+ + D G G+ YL+PE L ++ Y Sbjct: 426 LKLDNLVVDS---NCFVKIIDFGSAVVFKYPFEADIVEATGVVGSDPYLAPETLVRKLYD 482 Query: 196 -KPVDIWACGVILYIL-LVGYP---PFWDEDQYRLYAQIKAGAYDYPSP 239 + VDIW+ +I + L +P P ++ +RL+ +K + D SP Sbjct: 483 PRAVDIWSSAIIFCCMALRRFPWKYPKLSDNSFRLFC-MKQPSNDAESP 530 >SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein kinase Ppk5 |Schizosaccharomyces pombe|chr 1|||Manual Length = 836 Score = 76.6 bits (180), Expect = 8e-15 Identities = 59/207 (28%), Positives = 96/207 (46%), Gaps = 12/207 (5%) Query: 17 YELKEELGKGAFSIVRRAVQKSTGYEFAAKII-NTKKLSARDFQKLEREARICRK--LQH 73 YE+ + +GKG+F V + + G A K+I N +K + ++ R+C Sbjct: 518 YEIIDTVGKGSFGQVLKCIDHKRGQVVAIKVIKNRQKFHGQTLVEVGILKRLCEADPADK 577 Query: 74 PNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEAD---ASHCIQQILESVHHC 130 N++R + S + H + + G LF D++ Y Q L+++ Sbjct: 578 NNVIR-YLSHFDFRGHLCIVTELLGSNLF-DVIRENNYKGLPLIVVKSFALQGLQALRLL 635 Query: 131 HHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLK 190 ++H DLKPENLLL+ K A +KL DFG + + + + + Y +PE++ Sbjct: 636 QGQNIIHCDLKPENLLLSHPLK-ARIKLIDFGSSCFYN---EKVYTYLQSRFYRAPEIIL 691 Query: 191 KEPYGKPVDIWACGVILYILLVGYPPF 217 YGK +DIW+ G IL L G P F Sbjct: 692 GLEYGKEIDIWSFGCILAELFTGVPLF 718 >SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating kinase Crk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 335 Score = 76.6 bits (180), Expect = 8e-15 Identities = 57/203 (28%), Positives = 95/203 (46%), Gaps = 11/203 (5%) Query: 17 YELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLS-ARDFQKLEREARICRKLQHPN 75 Y + ++G+G +++V QK T A K I + D L RE + R+ +H N Sbjct: 11 YVKERKVGEGTYAVVFLGRQKETNRRVAIKKIKVGQFKDGIDISAL-REIKFLRESRHDN 69 Query: 76 IVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREF--YSEADASHCIQQILESVHHCHHN 133 ++ L D + ++ + + E ++ +F + A + +L +HH H Sbjct: 70 VIELVDVFSTKSNLNIILEFLDSD--LEMLIKDKFIVFQPAHIKSWMVMLLRGLHHIHSR 127 Query: 134 GVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEV-LKKE 192 ++HRDLKP NLL++S +KLADFGL+ + G T Y PE+ + Sbjct: 128 FILHRDLKPNNLLISS---DGVLKLADFGLSRDF-GTPSHMSHQVITRWYRPPELFMGCR 183 Query: 193 PYGKPVDIWACGVILYILLVGYP 215 YG VD+W+ G I L++ P Sbjct: 184 SYGTGVDMWSVGCIFAELMLRTP 206 >SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Schizosaccharomyces pombe|chr 1|||Manual Length = 332 Score = 76.2 bits (179), Expect = 1e-14 Identities = 77/303 (25%), Positives = 138/303 (45%), Gaps = 55/303 (18%) Query: 13 FSDNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQ 72 + DNYE+ ++G+G +S V + + K++ K ++K++RE +I + L Sbjct: 39 YQDNYEIIRKVGRGKYSEVFEGLNVLNNSKCIIKVLKPVK-----YKKIKREIKILQNLA 93 Query: 73 H-PNIVRLHDSIQ--EEHCHYLVFDLVTGGELFEDIVAREFY---SEADASHCIQQILES 126 PNI+ L D ++ E L+F+ V ++I R Y S+ D + ++L++ Sbjct: 94 GGPNIISLLDIVRDPESKTPSLIFEFV------DNIDFRTLYPTLSDYDIRYYSYELLKA 147 Query: 127 VHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSP 186 + CH G++HRD+KP N+++ K + ++L D+GLA E + + + P Sbjct: 148 LDFCHSRGIMHRDVKPHNVMIDHKKR--KLRLIDWGLA-EFYHAGMEYNVRVASRYFKGP 204 Query: 187 EVLKK-EPYGKPVDIWACGVILYILLVGYPPFW-DEDQY-------------RLYAQIKA 231 E+L Y +DIW+ GV+ L+ F+ D Y L+A ++ Sbjct: 205 ELLVDFREYDYSLDIWSFGVMFAALIFKKDTFFRGRDNYDQLVKIAKVLGTDELFAYVQK 264 Query: 232 ------GAYD-----YPSPEW---------DTVTPEAKSLINQMLTVNPSKRITASEALK 271 YD YP +W EA L+N++L + +R+T EA+ Sbjct: 265 YQIVLDRQYDNILGQYPKRDWYSFVNRDNRSLANDEAIDLLNRLLRYDHQERLTCQEAMA 324 Query: 272 HPW 274 HP+ Sbjct: 325 HPY 327 >SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 422 Score = 74.9 bits (176), Expect = 2e-14 Identities = 80/298 (26%), Positives = 135/298 (45%), Gaps = 41/298 (13%) Query: 16 NYELKEELGKGAFSIV---RRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQ 72 N+++ +ELG+GA+ IV R K KI N S + L + Sbjct: 20 NFKVVKELGQGAYGIVCAARNVASKDQEAVAIKKITNVFSKSILTKRALREIKLLIHFRN 79 Query: 73 HPNIVRLHDS--IQEEHCHYL-VFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHH 129 H NI ++D I + + + +++ + +L I + + ++A I QIL + + Sbjct: 80 HRNITCIYDLDIINPYNFNEVYIYEELMEADLNAIIKSGQPLTDAHFQSFIYQILCGLKY 139 Query: 130 CHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGF----AGTPGYLS 185 H V+HRDLKP NLL+ + + +K+ DFGLA + + GF T Y + Sbjct: 140 IHSANVIHRDLKPGNLLVNADCE---LKICDFGLARGCSENPEENPGFMTEYVATRWYRA 196 Query: 186 PEV-LKKEPYGKPVDIWACGVILYILLVGYPPFW------------------DEDQYRLY 226 PE+ L Y K +D+W+ G IL LL G P F DE+ Sbjct: 197 PEIMLSFSSYHKGIDVWSVGCILAELLGGTPLFKGKDFVHQLNLILHQLGTPDEETLSHI 256 Query: 227 AQIKAGAYDYPSPE-----WDTVTPEAK----SLINQMLTVNPSKRITASEALKHPWI 275 + +A Y P+ ++T P+A L+ ++L +P++RI+ +AL+HP++ Sbjct: 257 SSSRAQEYVRSLPKQRPIPFETNFPKANPLALDLLAKLLAFDPNRRISVDDALEHPYL 314 >SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosaccharomyces pombe|chr 1|||Manual Length = 469 Score = 73.3 bits (172), Expect = 7e-14 Identities = 60/233 (25%), Positives = 109/233 (46%), Gaps = 19/233 (8%) Query: 11 TRFS-DNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARD-FQKLEREARIC 68 TR S +++ + +GKGAF VR + TG +A K + ++ RD ++ E + Sbjct: 86 TRLSLEDFSTIKVIGKGAFGEVRLVQKLDTGKIYAMKSLLKTEMFKRDQLAHVKAERDLL 145 Query: 69 RKLQHPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVH 128 + P +V L+ + Q+ YL+ + + GG+L ++ + +SE + + + ++ Sbjct: 146 VESDSPWVVSLYYAFQDSLYLYLIMEFLPGGDLMTMLINYDTFSEDVTRFYMAECVLAIA 205 Query: 129 HCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEV 188 H G +HRD+KP+N+L+ + +KL+DFGL+ Q + Y+ P Sbjct: 206 DVHRMGYIHRDIKPDNILI---DRDGHIKLSDFGLSTGFYKQDQ-------SASYMKPRT 255 Query: 189 LKKEPYGKPVD-IWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPE 240 G+ VD IW L + W +++ R+ A G DY +PE Sbjct: 256 GNTVKRGQMVDAIW-----LTMSSKDKMATWKKNR-RVMAYSTVGTPDYIAPE 302 Score = 63.7 bits (148), Expect = 6e-11 Identities = 30/102 (29%), Positives = 58/102 (56%), Gaps = 2/102 (1%) Query: 175 FGFAGTPGYLSPEVLKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAY 234 + GTP Y++PE+ ++ YG+ D W+ G I++ L+G+PPF E+ + Y +I Sbjct: 290 YSTVGTPDYIAPEIFLQQGYGQDCDWWSLGAIMFECLIGWPPFCSENSHETYRKIINWRE 349 Query: 235 DYPSPEWDTVTPEAKSLINQMLTVNPSK--RITASEALKHPW 274 P ++ EA+ L+++++T + + R A E ++HP+ Sbjct: 350 TLTFPNDIHLSIEARDLMDRLMTDSEHRLGRGGAIEIMQHPF 391 >SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizosaccharomyces pombe|chr 2|||Manual Length = 381 Score = 72.9 bits (171), Expect = 1e-13 Identities = 81/296 (27%), Positives = 133/296 (44%), Gaps = 48/296 (16%) Query: 16 NYELKEELGKGAFSIVRRAVQKST-GYEFAAKIINTKKLSARDFQKLEREARICRKLQHP 74 +YE LG G+F +V +A T G+ +++ K+ R+ Q I R + HP Sbjct: 24 SYEPCRVLGSGSFGVVIQAKLVGTPGFIAVKRVLQDKRYKNRELQ-------IMRAISHP 76 Query: 75 NIVRL------HDSIQEEHCHYLVFDLVTGGELFEDI--VAREFYSEADASHCIQ--QIL 124 NI++L H+ ++E L+ + + +F+D+ R S + S + Q+ Sbjct: 77 NIIKLIAFFHTHNPSKDETHLCLLLEYMPE-TVFDDMRWYTRRRKSIPNLSIKLYAFQLF 135 Query: 125 ESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYL 184 ++ + H GV HRD+KP+NLL+ K +KL DFG A +V + + + Y Sbjct: 136 RALAYLHSTGVCHRDIKPQNLLVDYKT--GILKLCDFGSA-KVLVPSEPNVSYICSRYYR 192 Query: 185 SPE-VLKKEPYGKPVDIWACGVILYILLVGYPPF-WDEDQYRL-----------YAQIKA 231 +PE V Y +D+W+ ++ L +G P F D +L Y +I Sbjct: 193 APELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIRVLGTPSYHEISV 252 Query: 232 GAYDYPSPEWDTVTP-------------EAKSLINQMLTVNPSKRITASEALKHPW 274 +Y + V P A L+++MLT PSKRI+A E L HP+ Sbjct: 253 MNPNYVNHSLPNVRPHTLESVMPHNCTKNAMDLLHKMLTYVPSKRISAIEVLTHPF 308 >SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity protein kinase Mph1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 678 Score = 72.5 bits (170), Expect = 1e-13 Identities = 73/286 (25%), Positives = 115/286 (40%), Gaps = 37/286 (12%) Query: 23 LGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQ-HPNIVRLHD 81 +GKG S+V R +A K +N Q + E + RKL + I++L+ Sbjct: 322 VGKGGSSMVYRIFSPDNSRLYALKEVNFINADQTTIQGYKNEIALLRKLSGNDRIIKLYA 381 Query: 82 SIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCI---QQILESVHHCHHNGVVHR 138 + + L + G +++ + + + +Q+LE+V H +VH Sbjct: 382 AEVNDTLGQLNMVMECGETDLANLLMKNMKKPINLNFIRMYWEQMLEAVQVVHDQNIVHS 441 Query: 139 DLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWF--GFAGTPGYLSPEVL------- 189 DLKP N LL +KL DFG+A + D GT Y++PE L Sbjct: 442 DLKPANFLLVE----GNLKLIDFGIAKAIGNDTTNIHRDSHIGTINYMAPEALTDMNAHT 497 Query: 190 ----KKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPE----- 240 K G+P D+W+ G ILY ++ G PF + A I Y PE Sbjct: 498 NSGVKLVKLGRPSDVWSLGCILYQMVYGRAPFAHLKMIQAIAAIPNEQYHIHFPEVALPA 557 Query: 241 -----------WDTVTPEAKSLINQMLTVNPSKRITASEALKHPWI 275 TV P+ ++ + L + KR+T E L HP++ Sbjct: 558 NAVQEKEGSLPGVTVGPDLMDVMKRCLERDQRKRLTIPELLVHPFL 603 >SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schizosaccharomyces pombe|chr 1|||Manual Length = 387 Score = 72.1 bits (169), Expect = 2e-13 Identities = 81/313 (25%), Positives = 141/313 (45%), Gaps = 46/313 (14%) Query: 16 NYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQHPN 75 +Y + +G G+F +V + + + A K + L + F+ RE +I R ++HPN Sbjct: 31 SYTSSKVVGSGSFGVVMQVHLIESDSKAAIKRV----LQDKRFKN--RELQIMRIMKHPN 84 Query: 76 IVRL-------HDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEA--DASHCIQQILES 126 IV L D+ E + + ++ + + R+ S + I Q+L S Sbjct: 85 IVDLIAYYYTTGDNSDEVYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQLLRS 144 Query: 127 VHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLA-IEVQGDQQAWFGFAGTPGYLS 185 + + H +G+ HRD+KP+NLLL + +KL DFG A I V G+ + + Y + Sbjct: 145 LAYIHASGICHRDIKPQNLLL--DPENGILKLCDFGSAKILVAGEPNV--SYICSRYYRA 200 Query: 186 PE-VLKKEPYGKPVDIWACGVILYILLVGYPPFWDE---DQ----YRLYA-----QIKAG 232 PE + Y +DIW+ G ++ L++G+P F E DQ ++ QIK Sbjct: 201 PELIFGATDYTHAIDIWSTGCVMAELMLGHPLFPGESGIDQLVEIIKILGTPSREQIKTM 260 Query: 233 AYDYPSPEWDTVTP-------------EAKSLINQMLTVNPSKRITASEALKHPWICHRE 279 +Y + + P +A L+++ML P+ R+TA+EA+ HP+ Sbjct: 261 NPNYMEHRFPQIRPQPLSRVFSRSVPLDALDLLSKMLQYTPTDRLTAAEAMCHPFFDELR 320 Query: 280 RVASVMHRQETVD 292 + +H D Sbjct: 321 DPNTKLHNSRNPD 333 >SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1316 Score = 71.7 bits (168), Expect = 2e-13 Identities = 39/101 (38%), Positives = 52/101 (51%), Gaps = 3/101 (2%) Query: 177 FAGTPGYLSPEVLKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDY 236 F GTP YL+PE L+ VD WA G +L+ L GYPPF E +++ I A + Sbjct: 831 FVGTPDYLAPETLRGSTQDDMVDWWALGCVLFEFLFGYPPFHAETPEKVFENILANNIAW 890 Query: 237 PSPEWDTVTPEAKSLINQMLTVNPSKRITAS---EALKHPW 274 P E + EA LIN L NP +R+ S E +HP+ Sbjct: 891 PDLEMYPCSEEALDLINGFLQPNPERRLGFSDINEIKEHPF 931 Score = 67.3 bits (157), Expect = 5e-12 Identities = 40/151 (26%), Positives = 76/151 (50%), Gaps = 5/151 (3%) Query: 16 NYELKEELGKGAFSIVRRAVQKSTGYEFAAKIIN-TKKLSARDFQKLEREARICRKLQHP 74 +YE+ + + KG F V + + +TG +A K++ +S ++ E + + Sbjct: 563 DYEIIKPISKGTFGTVYLSRKNTTGEIYAIKVLRKVDMISKNQVANVKAERAVLMAQEES 622 Query: 75 NIV-RLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHN 133 V +L+ + Q YLV + + GG+ + + E+ A I ++ + H H Sbjct: 623 AFVAKLYYAFQSRDYLYLVMEFMNGGDCASLLKSLYTIPESWAKIYIAEVALGLEHLHRL 682 Query: 134 GVVHRDLKPENLLLASKAKGAAVKLADFGLA 164 G++HRD+KP+N+L++ +KLADFGL+ Sbjct: 683 GIIHRDIKPDNILMSITGH---LKLADFGLS 710 >SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 363 Score = 67.7 bits (158), Expect = 4e-12 Identities = 71/273 (26%), Positives = 117/273 (42%), Gaps = 22/273 (8%) Query: 23 LGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDS 82 LG+G VR+ + T FA K + +A Q L RE +I R P IV+ + + Sbjct: 85 LGEGVSGSVRKCRIRGTQMIFAMKTVLAAPNTALQKQLL-RELKINRSCTSPYIVKYYGA 143 Query: 83 IQEE-HCHY-LVFDLVTGGELFEDIVAREFYS------EADASHCIQQILESVHHCHHNG 134 C + + G L D + + S E +L + + H Sbjct: 144 CYNNAECQLNIAMEYCGAGSL--DAIYKRVRSQGGRTGERPLGKIAFGVLSGLSYLHDRK 201 Query: 135 VVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEPY 194 ++HRD+KP N+LL SK + VKL DFG++ E+ F GT Y++PE + Y Sbjct: 202 IIHRDIKPSNILLTSKGQ---VKLCDFGVSGELVNSLAG--TFTGTSYYMAPERISGGSY 256 Query: 195 GKPVDIWACGVILYILLVGYPPFWDE-DQYRLYAQIKAGAYDYPSP--EWDTVTPEAKSL 251 DIW+ G+ L + + PF E + ++ + + P P + +KS Sbjct: 257 TISSDIWSLGLTLMEVALNRFPFPPEGSPPPMPIELLSYIINMPPPLLPQEPGIKWSKSF 316 Query: 252 INQM---LTVNPSKRITASEALKHPWICHRERV 281 + + L + ++R + L HPW+ ER+ Sbjct: 317 QHFLCVCLDKDKTRRPGPQKMLTHPWVKAFERI 349 >SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizosaccharomyces pombe|chr 3|||Manual Length = 1338 Score = 66.9 bits (156), Expect = 6e-12 Identities = 35/101 (34%), Positives = 59/101 (58%), Gaps = 3/101 (2%) Query: 177 FAGTPGYLSPEVLKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDY 236 F GTP Y++PEV+ P K D W+ G +++ L GYPPF E +++ I A ++ Sbjct: 857 FIGTPDYIAPEVILGNPGIKASDWWSLGCVVFEFLFGYPPFNAETPDQVFQNILARRINW 916 Query: 237 PSPEWDTVTPEAKSLINQMLTVNPSKRITAS--EALK-HPW 274 P+ + + A LI+++L +NP+ R+ A+ E +K HP+ Sbjct: 917 PAEVFTAESSVALDLIDRLLCMNPANRLGANGVEEIKAHPF 957 Score = 66.5 bits (155), Expect = 8e-12 Identities = 41/152 (26%), Positives = 77/152 (50%), Gaps = 5/152 (3%) Query: 15 DNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARD--FQKLEREARICRKLQ 72 ++Y++ + + KGAF V A +++TG FA KI+ + A++ A + + + Sbjct: 587 NDYKILKPISKGAFGSVYLAQKRTTGDYFAIKILKKSNMIAKNQVINVRAERAILMSQGE 646 Query: 73 HPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHH 132 P + +L+ + Q + YLV + + GG+ + I + + + H Sbjct: 647 SPFVAKLYYTFQSKDYLYLVMEYLNGGDCGSLLKTMGVLDLDWIRTYIAETVLCLGDLHD 706 Query: 133 NGVVHRDLKPENLLLASKAKGAAVKLADFGLA 164 G++HRD+KPENLL+ ++ +KL DFGL+ Sbjct: 707 RGIIHRDIKPENLLI---SQNGHLKLTDFGLS 735 >SPAC823.03 |ppk15||serine/threonine protein kinase Ppk15 |Schizosaccharomyces pombe|chr 1|||Manual Length = 534 Score = 66.5 bits (155), Expect = 8e-12 Identities = 61/222 (27%), Positives = 97/222 (43%), Gaps = 17/222 (7%) Query: 17 YELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQHP-- 74 Y + + LG G F V R T A K+I K + + E I L + Sbjct: 130 YLILDTLGHGTFGQVARCQDLKTQQIVAIKVIKNKPAF---YNQCVMEVSILELLNNKYD 186 Query: 75 -----NIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSE--ADASHCIQQILESV 127 +++RL+D ++ LVF+L++ L+E I +F + Q+L Sbjct: 187 PEDKRHLIRLYDQFMHKNHLCLVFELLSIN-LYELIKQNQFRGLHLSLVRSFATQLLSCT 245 Query: 128 HHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPE 187 ++H DLKPEN+LL + VK+ DFG A ++Q + + + Y SPE Sbjct: 246 SLLKQARIIHCDLKPENILLQDLSS-PIVKVIDFGSACH---ERQTVYTYIQSRFYRSPE 301 Query: 188 VLKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQI 229 V+ Y +D+W+ G IL L +G P F +Y +I Sbjct: 302 VILGLHYNCGIDMWSLGCILAELFLGLPLFPGNSEYNQLCRI 343 Score = 27.9 bits (59), Expect = 3.5 Identities = 12/24 (50%), Positives = 15/24 (62%) Query: 252 INQMLTVNPSKRITASEALKHPWI 275 I Q L +NP KR T +A HP+I Sbjct: 435 IKQFLELNPLKRWTPDQAKNHPFI 458 >SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1072 Score = 66.1 bits (154), Expect = 1e-11 Identities = 83/288 (28%), Positives = 121/288 (42%), Gaps = 44/288 (15%) Query: 21 EELGKGAF-SIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRL 79 E +G G+ +IV R V + ++ L++R+ L++ HPNIVR Sbjct: 658 EVIGYGSHGTIVYRGVYEDREVAVKRVLMEFYDLASREITLLQQSDN------HPNIVRY 711 Query: 80 HDSIQEEHCHYLVFDLVTGG--ELFEDIVARE-FYSEADASHCIQQILESVHHCHHNGVV 136 + + + Y+V +L +L E +A + + D + QI V H H +V Sbjct: 712 YCKQKSDQFLYIVIELCKCNLSDLIEKPIAYDDLFKSIDLVSLLYQIAFGVSHLHSLDLV 771 Query: 137 HRDLKPENLLLA-------SKAKGAAVKLADFGLAIEVQGDQQA----WFGFAGTPGYLS 185 HRDLKP+N+LL SK + A+ ++DFGL+ ++ +Q + F AG+ G+ S Sbjct: 772 HRDLKPQNILLVVNNSPNLSKTRVRAL-ISDFGLSKKLDFNQSSLRNTTFEAAGSYGWRS 830 Query: 186 PEVL-------KKEPYGK-----------PVDIWACGVILYILLV-GYPPFWDEDQYRLY 226 PE+L KE K DI+A G I Y L G PF Y Sbjct: 831 PEILSGSLSQQSKEIQVKTREGRIRQASHATDIFALGCIFYYTLTGGMHPF--GSHYDCE 888 Query: 227 AQIKAGAYDYPS-PEWDTVTPEAKSLINQMLTVNPSKRITASEALKHP 273 I G Y A LI M+ PSKR T L HP Sbjct: 889 GNILKGNYCLVHLQSLGECGVLAADLIEDMIAFEPSKRPTIEVVLNHP 936 >SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosaccharomyces pombe|chr 3|||Manual Length = 877 Score = 66.1 bits (154), Expect = 1e-11 Identities = 57/193 (29%), Positives = 91/193 (47%), Gaps = 14/193 (7%) Query: 23 LGKGAFSIVRRA---VQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQ-HPNIVR 78 LG G FS V + V+K+ Y A K + K ++ +L +E I R L+ H +IV Sbjct: 572 LGSGEFSEVFQVEDPVEKTLKY--AVKKLKVKFSGPKERNRLLQEVSIQRALKGHDHIVE 629 Query: 79 LHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILE---SVHHCHHNGV 135 L DS + Y+ +L G L + + S D + ++E + HH Sbjct: 630 LMDSWEHGGFLYMQVELCENGSLDRFLEEQGQLSRLDEFRVWKILVEVALGLQFIHHKNY 689 Query: 136 VHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEPYG 195 VH DLKP N+++ + +K+ DFG+A V + G Y++PEVL Y Sbjct: 690 VHLDLKPANVMITFEG---TLKIGDFGMA-SVWPVPRG-MEREGDCEYIAPEVLANHLYD 744 Query: 196 KPVDIWACGVILY 208 KP DI++ G+ ++ Sbjct: 745 KPADIFSLGITVF 757 >SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase Srb10 |Schizosaccharomyces pombe|chr 1|||Manual Length = 352 Score = 64.9 bits (151), Expect = 3e-11 Identities = 58/228 (25%), Positives = 103/228 (45%), Gaps = 21/228 (9%) Query: 15 DNYELKEELGKGAFSIVRRAVQKSTGYE--FAAKIIN--TKKLSARD-----FQKLEREA 65 D Y++ + G + V +AV ++ + FA K +K++S+ Q RE Sbjct: 3 DGYKIIGFISSGTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIREM 62 Query: 66 RICRKLQHPNIVRLHDSIQEEHCHYLVFDLVTGGEL----FEDIVAREFYSEADASHCIQ 121 +CR++QH NIV L + ++ +VF+ L F + + Sbjct: 63 MLCREIQHENIVSLVQVLLKDGTISMVFEYAEHDLLQIIHFHSRSRTRQIPPSILKSILW 122 Query: 122 QILESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFG---FA 178 QI+ V + H N ++HRDLKP N+++ + K VK+ D GL ++ ++ Sbjct: 123 QIINGVAYLHENWIMHRDLKPANIMITATGK---VKIGDLGLGRLIRDPILPFYSSDRVV 179 Query: 179 GTPGYLSPE-VLKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRL 225 T Y +PE +L Y +D+WA G I Y ++ P + D+ ++ Sbjct: 180 VTIWYRAPELLLGAHDYTPAIDVWAIGCI-YGEMLALSPLFKGDEIKM 226 Score = 30.7 bits (66), Expect = 0.50 Identities = 16/38 (42%), Positives = 23/38 (60%), Gaps = 4/38 (10%) Query: 239 PEW-DTVT---PEAKSLINQMLTVNPSKRITASEALKH 272 P+W TV P+ L+ +ML +P RITA +AL+H Sbjct: 279 PQWYQTVKNRDPQGLDLLMKMLQYDPKSRITAKQALEH 316 >SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|Schizosaccharomyces pombe|chr 3|||Manual Length = 624 Score = 64.9 bits (151), Expect = 3e-11 Identities = 40/158 (25%), Positives = 76/158 (48%), Gaps = 4/158 (2%) Query: 16 NYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSA-RDFQKLEREARICRKLQHP 74 +++L +LG+G + V A +++T A K++ L + + + E I Sbjct: 161 HFDLLVKLGQGGYGSVWLAKKRNTHELLAMKMMKKSTLQQLNEVKHILNERDILTNTNSE 220 Query: 75 NIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNG 134 +V+L+ + Q++ YL + V GG+ + + E + +++ ++ H G Sbjct: 221 WLVKLYYAFQDKEKVYLAMEYVPGGDFRTFLTTKGLLHENQTRFYLAEMVAAISAVHKLG 280 Query: 135 VVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQ 172 +HRDLKPEN L+ K +KL+DFGL+ + Q Sbjct: 281 YMHRDLKPENFLIDQKGH---IKLSDFGLSTAIVTSNQ 315 Score = 52.8 bits (121), Expect = 1e-07 Identities = 38/109 (34%), Positives = 55/109 (50%), Gaps = 16/109 (14%) Query: 179 GTPGYLSPEVLKKEPYGKPVDIWACGVILYILLVGYPPF----WDEDQYRLY-------- 226 G+P Y++PEV+ + Y + VD W+ G I Y LVGYPPF E LY Sbjct: 359 GSPEYMAPEVVYGKKYDRTVDYWSLGCICYECLVGYPPFSGSTLQETWTNLYYWREMLQR 418 Query: 227 -AQIKAGAYDYPSPEWDTVTPEAKSLINQMLTVNPSKRITASEALKHPW 274 ++ + G YD + +V+ EA S I + LT S+ + E KHP+ Sbjct: 419 PSKNENGIYDKKA---RSVSDEAWSFITKCLTEPTSRFQSTIEIQKHPF 464 >SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizosaccharomyces pombe|chr 2|||Manual Length = 591 Score = 64.1 bits (149), Expect = 4e-11 Identities = 81/323 (25%), Positives = 137/323 (42%), Gaps = 59/323 (18%) Query: 4 PNRESVSTRFSDNYELKEELGKGAFSIVRRAVQKSTGYEFAAK--IINTKKLSARDFQKL 61 P V +Y L E+LG+G F V ++ ++ G +A K +++T+K + Sbjct: 23 PKLHFVGCSHLTDYHLMEKLGEGTFGEVYKSQRRKDGKVYALKRILMHTEK-EGFPITAI 81 Query: 62 EREARICRKLQHPNIVRLHDS--IQEEHCH------YLVFDLVTG--GELFEDIVAREFY 111 RE +I + ++H NI+ L D ++ + H Y+V + L E+ + + Sbjct: 82 -REIKILKSIKHENIIPLSDMTVVRADKKHRRRGSIYMVTPYMDHDLSGLLENPSVK--F 138 Query: 112 SEADASHCIQQILESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQ 171 +E ++Q+ + H ++HRDLK NLL+ + +K+ADFGLA + + Sbjct: 139 TEPQIKCYMKQLFAGTKYLHDQLILHRDLKAANLLIDNH---GILKIADFGLARVITEES 195 Query: 172 QA-------------WFGFAGTPGYLSPEVLKKE-PYGKPVDIWACGVILYILLVGYPPF 217 A + G T Y SPE+L E Y +D+W+ G I+ + G P Sbjct: 196 YANKNPGLPPPNRREYTGCVVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEMYKGRPIL 255 Query: 218 W---DEDQYRLYAQIKAGAYDYPSPEWD-----------------------TVTPEAKSL 251 D DQ ++ P W+ T E SL Sbjct: 256 QGSSDLDQLDKIFRLCGSPTQATMPNWEKLPGCEGVRSFPSHPRTLETAFFTFGKEMTSL 315 Query: 252 INQMLTVNPSKRITASEALKHPW 274 +LT+NP +R++AS AL+H + Sbjct: 316 CGAILTLNPDERLSASMALEHEY 338 >SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1032 Score = 62.5 bits (145), Expect = 1e-10 Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 5/162 (3%) Query: 15 DNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKL-SARDFQKLEREARICRKLQH 73 D + L +E+ +GA+ V A ++S+G FA K+I L S + + L E R ++ Sbjct: 526 DEFILLKEINRGAYGRVYLAKKRSSGKYFALKMIPKSSLDSLKKIKGLLLEKRNMHIQRY 585 Query: 74 -PNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHH 132 PN V+L+ + LV D GG+ I E ++L ++ H Sbjct: 586 GPNTVKLYYAFDSGDYLCLVMDYFNGGDCETLIQKLGPLPEQWVCQYAAELLNAIELLHQ 645 Query: 133 NGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAW 174 +G++H D+KP N+L+ ++L DFGL+ V+ ++ + Sbjct: 646 DGIIHHDIKPANMLVDETGH---IRLTDFGLSENVEEKKEVY 684 Score = 48.4 bits (110), Expect = 2e-06 Identities = 28/100 (28%), Positives = 54/100 (54%), Gaps = 4/100 (4%) Query: 178 AGTPGYLSPEVLKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYP 237 +GTP Y++PE+L + DIWA G +++ +L G PF ++A+I+ + Sbjct: 778 SGTPNYMAPEILMGVDT-QMGDIWAMGCVIFEMLTGTRPFEANTVKAIWARIERNDIGWT 836 Query: 238 SPEWDTVTPEAKSLINQMLTVNPSKRITAS---EALKHPW 274 ++ + EA LI +++ + +KR+ ++ E KHP+ Sbjct: 837 KRVKESCSKEAVDLITKLMDPDCNKRLGSNGYQEIKKHPF 876 >SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gcn2 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1576 Score = 62.5 bits (145), Expect = 1e-10 Identities = 50/168 (29%), Positives = 87/168 (51%), Gaps = 23/168 (13%) Query: 121 QQILESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIE---VQGDQQAWFG- 176 +QILE++ + H G++HRDLKP N+ L VKL DFGLA E Q + W Sbjct: 754 RQILEALAYIHSRGMMHRDLKPGNIFLDENRN---VKLGDFGLATENENYQDNNDKWKNR 810 Query: 177 ---------FAGTPGYLSPEVLKKE---PYGKPVDIWACGVILYILLVGYPPFWDEDQYR 224 GT Y++PE+L + Y VD+++ G+IL+ + + + ++ R Sbjct: 811 QSADEDLTTGVGTALYVAPELLSRRNGVRYDAKVDMYSLGIILFEMCMTFST--SMERIR 868 Query: 225 LYAQIKAGAYDYPSP-EWDTVTPEAKSLINQMLTVNPSKRITASEALK 271 + I++ + +PS + + E K +I+ +L +P+KR ++ E L+ Sbjct: 869 IIDTIRSPSISFPSTFPFSRASHEFK-VIHCLLQHDPTKRPSSQELLE 915 Score = 34.3 bits (75), Expect = 0.041 Identities = 23/92 (25%), Positives = 46/92 (50%), Gaps = 2/92 (2%) Query: 6 RESVSTRFSDNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREA 65 R+SVS R+ ++E E LG+G F V + + G +A K + ++ ++ RE Sbjct: 546 RKSVS-RYETDFEELEFLGRGGFGEVVKVKNRIDGRFYAVKKL-VLLSDDKENSRILREV 603 Query: 66 RICRKLQHPNIVRLHDSIQEEHCHYLVFDLVT 97 +L H ++VR + + E + V ++++ Sbjct: 604 MTLSRLHHEHVVRYYTAWVETEANDTVTEIIS 635 Score = 31.1 bits (67), Expect = 0.38 Identities = 27/102 (26%), Positives = 41/102 (40%), Gaps = 12/102 (11%) Query: 123 ILESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGF----- 177 ILE + H G+ H+ L +N++L KL DFG ++ D A F Sbjct: 358 ILEGLAELHRLGISHKSLHLDNVVLFHSGHRTFAKLMDFGFTRTLR-DMNASHPFNINSQ 416 Query: 178 ----AGTPGYLSPEVLKKE--PYGKPVDIWACGVILYILLVG 213 G PEV + + DIW G+++ +L G Sbjct: 417 SITNILPEGLYPPEVSESSFAAASRKTDIWCFGLLVLQMLCG 458 >SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schizosaccharomyces pombe|chr 1|||Manual Length = 690 Score = 60.5 bits (140), Expect = 5e-10 Identities = 61/232 (26%), Positives = 96/232 (41%), Gaps = 31/232 (13%) Query: 10 STRFSDNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICR 69 +++F++ Y + LG G F V + +STG A K+ T+ + L E R+ + Sbjct: 355 NSKFANRYTVVRLLGHGTFGKVIQCYDQSTGRHCAIKV--TRAIPKYREASLI-ELRVLQ 411 Query: 70 KLQHPNIVRLHDSIQ-----EEHCHYLVFDLVTGGELFEDIVAREFYSEADASHC---IQ 121 + H + + IQ + H + + G +F D + Y H Q Sbjct: 412 TIAHSDPTNENKCIQLRDYFDYRKHICIVTDLFGWSVF-DFLKNNNYIPFPLKHIQMLSQ 470 Query: 122 QILESVHHCHHNGVVHRDLKPENLLLASKA----------------KGAAVKLADFGLAI 165 Q+ +SV H G+VH DLKPEN+LL S A ++L DFG A Sbjct: 471 QLFKSVAFLHSLGLVHTDLKPENVLLVSNASRTIRLPYRNYSQKVLNSCEIRLIDFGSA- 529 Query: 166 EVQGDQQAWFGFAGTPGYLSPEVLKKEPYGKPVDIWACGVILYILLVGYPPF 217 + + T Y +PE++ + P D+W+ G IL L G F Sbjct: 530 --TFEDEYHSSVVSTRHYRAPEIILGLGWSYPCDVWSIGCILVELFTGQALF 579 Score = 28.7 bits (61), Expect = 2.0 Identities = 11/24 (45%), Positives = 17/24 (70%) Query: 251 LINQMLTVNPSKRITASEALKHPW 274 L+ ++ +P +RITA EAL HP+ Sbjct: 658 LLKKVFVYDPKRRITAKEALWHPF 681 >SPBC119.07 |ppk19||serine/threonine protein kinase Ppk19|Schizosaccharomyces pombe|chr 2|||Manual Length = 1706 Score = 60.1 bits (139), Expect = 7e-10 Identities = 68/268 (25%), Positives = 112/268 (41%), Gaps = 18/268 (6%) Query: 17 YELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTK--KLSARDFQKLEREARICRKLQHP 74 Y + LG F R +Q GY+ K+ K ++S L +E + + P Sbjct: 24 YHNERSLGDSHFLRTFR-MQDRKGYDVLIKVFVNKLPEISLSSIVNLLKEEQENISYRVP 82 Query: 75 NIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNG 134 N V ++ YLV VT L++ I R F + + Q+L+ + CH G Sbjct: 83 NAVPYIKTLVTLRAAYLVRPYVTHN-LYDRISTRPFLELTEKKWIMFQLLKGISDCHRLG 141 Query: 135 VVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFG-FAGTPG----YLSPE-- 187 V H D+K EN+L+ S + F + D A +G F T ++PE Sbjct: 142 VCHGDIKSENILITSWNWAYLSDFSSF-KPTYLPEDNPADYGYFFDTSSRRVCNIAPERF 200 Query: 188 ----VLKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDT 243 L+ P +DI++ G + LL+ P + Q L++ G+YD S Sbjct: 201 VPASQLQPAPLSPAMDIFSLGCVFAELLLEESPLFTLSQ--LFSYKAHGSYDLQSVLEQI 258 Query: 244 VTPEAKSLINQMLTVNPSKRITASEALK 271 +++I ML +PS+R++A L+ Sbjct: 259 EDKSTQNMILSMLDRDPSQRLSADAYLQ 286 >SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosaccharomyces pombe|chr 3|||Manual Length = 477 Score = 58.4 bits (135), Expect = 2e-09 Identities = 50/207 (24%), Positives = 95/207 (45%), Gaps = 19/207 (9%) Query: 17 YELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQ---- 72 Y ++ LGKG FS V A+ ++ FA KII ++ ++ K E I +LQ Sbjct: 159 YIVQSNLGKGMFSTVVSALDRNRNQTFAIKIIRNNEVMYKEGLK---EVSILERLQAADR 215 Query: 73 --HPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQ----QILES 126 +I+ ++ +VF++++ DI+ + + + ++ Q+ + Sbjct: 216 EGKQHIIHYERHFMHKNHLCMVFEMLSLN--LRDILKKFGRNVGLSIKAVRLYAYQMFMA 273 Query: 127 VHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSP 186 + V+H D+KP+N+L+ K +K+ D G A + ++ + + Y +P Sbjct: 274 LDLLKQCNVIHSDIKPDNMLVNEKRN--ILKICDLGSASDASENEIT--PYLVSRFYRAP 329 Query: 187 EVLKKEPYGKPVDIWACGVILYILLVG 213 E++ PY P+D W+ G LY L G Sbjct: 330 EIILGFPYSCPIDTWSVGCSLYELYTG 356 Score = 30.3 bits (65), Expect = 0.66 Identities = 12/31 (38%), Positives = 18/31 (58%) Query: 244 VTPEAKSLINQMLTVNPSKRITASEALKHPW 274 + E L+ + L +NP KR+ ALKHP+ Sbjct: 443 IRQELMDLLEKCLELNPEKRVPPEVALKHPF 473 >SPBC337.04 |ppk27||serine/threonine protein kinase Ppk27 |Schizosaccharomyces pombe|chr 2|||Manual Length = 413 Score = 56.8 bits (131), Expect = 7e-09 Identities = 49/188 (26%), Positives = 81/188 (43%), Gaps = 17/188 (9%) Query: 44 AAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEEHCHYLVFDLVTGGELFE 103 ++K N KK + F++ E + L HP +V+L + LV + GG+L+ Sbjct: 138 SSKSQNEKKARVKVFRQ---EIWALKTLSHPCVVQLLNYYVSSAELILVENYCMGGDLYH 194 Query: 104 DIVAREF-YSEADASHCIQQILESVHHCHHNGVVHRDLKPENLLLA------------SK 150 +S +++ +V + H ++HRDLK EN+LL Sbjct: 195 YTKKHHSDFSLEFVGRIFSELVHTVAYLHSKCLIHRDLKLENILLTQPYNVIKTIDNWKN 254 Query: 151 AKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEPY-GKPVDIWACGVILYI 209 A ++++DF L+I V G+ Y PEV + G D W+ G++L+ Sbjct: 255 YPNALIQISDFELSIFVDSKNHLVQSSCGSQEYAPPEVYMGIAHDGFRADAWSLGIVLFA 314 Query: 210 LLVGYPPF 217 LL G PF Sbjct: 315 LLEGRLPF 322 >SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomyces pombe|chr 1|||Manual Length = 607 Score = 56.4 bits (130), Expect = 9e-09 Identities = 43/156 (27%), Positives = 71/156 (45%), Gaps = 5/156 (3%) Query: 11 TRFSD-NYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARD-FQKLEREARIC 68 TR S +++ ++G+G + V A ++ T A KI+N L D + + E I Sbjct: 201 TRISHGDFQTITQVGQGGYGSVWLARKRDTKEIVALKIMNKSVLHKMDEIRHVLTERDIL 260 Query: 69 RKLQHPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVH 128 +VRL + Q+ YL + V GG+ + + A ++ ++ Sbjct: 261 TTANSEWLVRLLYAFQDTSNIYLAMEFVPGGDFRTLLSNSGVLRDHHAKFYATEMFLAID 320 Query: 129 HCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLA 164 H G +HRDLKPEN L+ + +KL DFGL+ Sbjct: 321 ALHQLGYIHRDLKPENFLVGASGH---IKLTDFGLS 353 Score = 54.0 bits (124), Expect = 5e-08 Identities = 23/64 (35%), Positives = 36/64 (56%) Query: 179 GTPGYLSPEVLKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPS 238 G+P Y++PEVL+ E Y VD W+ G I+Y L G+PPF + ++ +K + Sbjct: 405 GSPDYMAPEVLRGENYNHSVDYWSLGCIMYECLSGFPPFSGSNVNETWSNLKNWRKCFQR 464 Query: 239 PEWD 242 P +D Sbjct: 465 PHYD 468 >SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomyces pombe|chr 2|||Manual Length = 581 Score = 53.2 bits (122), Expect = 8e-08 Identities = 43/166 (25%), Positives = 74/166 (44%), Gaps = 12/166 (7%) Query: 47 IINTKKLSARDFQKLER---EARICRKLQH-PNIVRLHDSIQEEHCHYLVFDLVTGGEL- 101 ++ K +A F ER E I ++LQ P +V L + +L D G+L Sbjct: 318 VVKMLKKNAAKFTGKERHLQEVSILQRLQACPFVVNLVNVWSYNDNIFLQLDYCENGDLS 377 Query: 102 --FEDIVAREFYSEADASHCIQQILESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLA 159 ++ + + Q+ ++++ H VH D+KP N+L+ + +KL Sbjct: 378 LFLSELGLLQVMDPFRVWKMLFQLTQALNFIHLLEFVHLDVKPSNVLIT---RDGNLKLG 434 Query: 160 DFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEPYGKPVDIWACGV 205 DFGLA + G Y++PE+L YGKP D+++ G+ Sbjct: 435 DFGLATSLPVSSMV--DLEGDRVYIAPEILASHNYGKPADVYSLGL 478 >SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosaccharomyces pombe|chr 2|||Manual Length = 365 Score = 52.4 bits (120), Expect = 1e-07 Identities = 42/161 (26%), Positives = 70/161 (43%), Gaps = 11/161 (6%) Query: 8 SVSTRFSDNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARI 67 ++ R + Y + ++G G+F + +G E A K+ +T+ +LE E R+ Sbjct: 2 ALDLRIGNKYRIGRKIGSGSFGDIYLGTNVVSGEEVAIKLESTRA----KHPQLEYEYRV 57 Query: 68 CRKLQHPNIVRLHDSIQEEHCHY--LVFDLVTGGELFEDIV--AREFYSEADASHCIQQI 123 R L + E C Y +V DL+ G ED+ +S Q+ Sbjct: 58 YRILSGGVGIPFVRWFGVE-CDYNAMVMDLL--GPSLEDLFNFCNRKFSLKTVLLLADQL 114 Query: 124 LESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLA 164 + + H +HRD+KP+N L+ +G V + DFGLA Sbjct: 115 ISRIEFIHSKSFLHRDIKPDNFLMGIGKRGNQVNIIDFGLA 155 >SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 340 Score = 51.6 bits (118), Expect = 3e-07 Identities = 26/71 (36%), Positives = 42/71 (59%), Gaps = 5/71 (7%) Query: 135 VVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEPY 194 ++HRDLKP N+++ S+ + +KL DFG++ E+ F GT Y+SPE ++ Y Sbjct: 182 IIHRDLKPSNVVVNSRGE---IKLCDFGVSGELVNSVAQTF--VGTSTYMSPERIRGGKY 236 Query: 195 GKPVDIWACGV 205 DIW+ G+ Sbjct: 237 TVKSDIWSLGI 247 >SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizosaccharomyces pombe|chr 2|||Manual Length = 953 Score = 49.6 bits (113), Expect = 1e-06 Identities = 72/277 (25%), Positives = 120/277 (43%), Gaps = 37/277 (13%) Query: 19 LKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQ-HPNIV 77 ++ L +G FS V A+ ++ F K I +A Q + E ++L+ H +IV Sbjct: 59 IQRYLSEGGFSHVYLALLENEK-PFVLKRIYVPDKTA--LQLVHGEIETMKRLKGHRHIV 115 Query: 78 RLHDSI------QEEHCHYLVFDLVTGGELFEDIVAREFY--SEADASHCIQQILESVHH 129 DS + + YL+ + GG L + + R + +E + + + ++V Sbjct: 116 NYIDSSALYSKSENRYEVYLLMEFCAGGGLIDFMNTRLQHRLTEGEILKILADVCDAVAA 175 Query: 130 CHHNG--VVHRDLKPENLLLASKAKGAAVKLADFGLAIE----------VQGDQQAWFGF 177 H+ ++HRDLK EN+LL + + KL DFG A E + +Q + Sbjct: 176 MHYLDPPLIHRDLKIENVLLVAP---NSYKLCDFGSACEPLAPATTPDTIMFLEQNIAAY 232 Query: 178 AGTPGYLSPEVL---KKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAY 234 TP Y +PE++ +++ + DIWA GV+ Y L PF +Q A +KA Sbjct: 233 T-TPQYRAPEMIDINRRQGIDEKSDIWAIGVLAYKLCYYTTPF---EQVGNSAILKA--- 285 Query: 235 DYPSPEWDTVTPEAKSLINQMLTVNPSKRITASEALK 271 + P + + K I L PS R + LK Sbjct: 286 SFSFPPFPRYSDRMKRFIATCLQEQPSHRPNIYQTLK 322 >SPAC20G4.03c |hri1||eIF2 alpha kinase Hri1|Schizosaccharomyces pombe|chr 1|||Manual Length = 704 Score = 49.6 bits (113), Expect = 1e-06 Identities = 25/72 (34%), Positives = 39/72 (54%) Query: 11 TRFSDNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRK 70 +R++ ++E E LGKG + V +A K G E+A K I + S + RE+R + Sbjct: 218 SRYASDFEELELLGKGGYGSVYKARNKFDGVEYALKKIPLRLRSFSTSSNIFRESRTLAR 277 Query: 71 LQHPNIVRLHDS 82 L HPN++R S Sbjct: 278 LNHPNVIRFFSS 289 Score = 30.3 bits (65), Expect = 0.66 Identities = 15/29 (51%), Positives = 20/29 (68%), Gaps = 1/29 (3%) Query: 122 QILESVHHCHHN-GVVHRDLKPENLLLAS 149 +ILE V + H +VHRDLKP N+ L+S Sbjct: 473 RILEGVLYLHDAMHLVHRDLKPRNIFLSS 501 >SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 306 Score = 48.0 bits (109), Expect = 3e-06 Identities = 42/145 (28%), Positives = 67/145 (46%), Gaps = 8/145 (5%) Query: 67 ICRKLQHPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILES 126 I + HP+I R+ DS + + L+T + F + S + QI + Sbjct: 59 ILESIGHPHIERIVDSFIDNEAGSVY--LITSFKSFVLSDVMDEISIDTKCKIVLQISSA 116 Query: 127 VHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQ--GDQ-QAWFGFAGTPGY 183 + + +G++HRD+ P N+LL S G A L+DF +A Q G++ Q GT Y Sbjct: 117 LEYLEKHGILHRDIHPNNILLDS-MNGPAY-LSDFSIAWSKQHPGEEVQELIPQIGTGHY 174 Query: 184 LSPEVL-KKEPYGKPVDIWACGVIL 207 + E L YG VD W G+++ Sbjct: 175 RAIETLFGCHSYGHEVDRWTFGILI 199 >SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces pombe|chr 1|||Manual Length = 639 Score = 47.2 bits (107), Expect = 5e-06 Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 1/76 (1%) Query: 7 ESVSTRFSDNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREAR 66 +S ++R+ +++E LG+G F V K G E+A K IN+ + K+ RE + Sbjct: 161 QSRNSRYIEDFEEYSLLGRGGFGSVYHVRNKIDGAEYAMKKINS-TFQQMSYSKIFREIK 219 Query: 67 ICRKLQHPNIVRLHDS 82 K+ HPN++R S Sbjct: 220 CLAKMDHPNVIRYFSS 235 Score = 28.3 bits (60), Expect = 2.7 Identities = 11/29 (37%), Positives = 18/29 (62%), Gaps = 1/29 (3%) Query: 121 QQILESVHHCHHN-GVVHRDLKPENLLLA 148 + I+ V + H ++HRD+KP N+ LA Sbjct: 398 RMIINGVMYVHEGVNLIHRDIKPSNIFLA 426 >SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 400 Score = 46.4 bits (105), Expect = 9e-06 Identities = 42/160 (26%), Positives = 72/160 (45%), Gaps = 13/160 (8%) Query: 9 VSTRFSDNYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARIC 68 V + + Y + ++G G+F + + G + A K+ + L AR Q LE E R+ Sbjct: 4 VDIKIGNKYRIGRKIGSGSFGQIYLGLNTVNGEQVAVKL---EPLKARHHQ-LEYEFRVY 59 Query: 69 RKLQ-HPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVA---REFYSEADASHCIQQIL 124 L+ + I + + +V DL+ G ED+ R+F + Q++ Sbjct: 60 NILKGNIGIPTIRWFGVTNSYNAMVMDLL--GPSLEDLFCYCGRKFTLKT-VLLLADQLI 116 Query: 125 ESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLA 164 + + H +HRD+KP+N L+ K V + DFGLA Sbjct: 117 SRIEYVHSKSFLHRDIKPDNFLM--KKHSNVVTMIDFGLA 154 >SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizosaccharomyces pombe|chr 2|||Manual Length = 435 Score = 43.2 bits (97), Expect = 9e-05 Identities = 40/154 (25%), Positives = 69/154 (44%), Gaps = 11/154 (7%) Query: 16 NYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQHPN 75 +Y + ++G+G+F ++ + A K KK A + R ++ + + Sbjct: 11 HYRVGRKIGEGSFGVIFDGMNLLNNQLIAIKF-EPKKSEAPQLRDEYRTYKLL--VGNAG 67 Query: 76 IVRLHDSIQEEHCHYLVFDLVTGGELFEDIV---AREFYSEADASHCIQQILESVHHCHH 132 I ++ QE + LV DL+ G ED+ R F S + +Q+L V H Sbjct: 68 IPNVYYFGQEGLHNILVIDLL--GPSLEDLFEWCGRRF-SVKTVAMTAKQMLSRVQTIHE 124 Query: 133 NGVVHRDLKPENLLLA--SKAKGAAVKLADFGLA 164 +V+RD+KP+N L+ S V + DFG+A Sbjct: 125 KNLVYRDIKPDNFLIGRPSSRNANMVYMVDFGMA 158 >SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizosaccharomyces pombe|chr 2|||Manual Length = 446 Score = 42.3 bits (95), Expect = 2e-04 Identities = 39/152 (25%), Positives = 69/152 (45%), Gaps = 9/152 (5%) Query: 16 NYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQH-P 74 +Y++ +G+G+F ++ + A K + D +L E R + L Sbjct: 11 HYKVGRRIGEGSFGVIFEGTNLLNNQQVAIKFEPRRS----DAPQLRDEYRTYKLLAGCT 66 Query: 75 NIVRLHDSIQEEHCHYLVFDLVTGG-ELFEDIVAREFYSEADASHCIQQILESVHHCHHN 133 I ++ QE + LV DL+ E D+ R+F S + +Q+L V H Sbjct: 67 GIPNVYYFGQEGLHNILVIDLLGPSLEDLLDLCGRKF-SVKTVAMAAKQMLARVQSIHEK 125 Query: 134 GVVHRDLKPENLLLA-SKAKGA-AVKLADFGL 163 +V+RD+KP+N L+ +K A + + DFG+ Sbjct: 126 SLVYRDIKPDNFLIGRPNSKNANMIYVVDFGM 157 >SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 507 Score = 40.7 bits (91), Expect = 5e-04 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 5/75 (6%) Query: 102 FEDIVAREFYSE---ADASHCIQQILESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKL 158 +E R++YS D S + + +++ G++HRD+KP N L + K L Sbjct: 176 YEHTDFRQYYSTFSYRDMSIYFRCLFQAMQQTQTLGIIHRDIKPSNFLFDVRTKHGV--L 233 Query: 159 ADFGLAIEVQGDQQA 173 DFGLA G QQ+ Sbjct: 234 VDFGLAERYDGRQQS 248 Score = 35.9 bits (79), Expect = 0.013 Identities = 22/46 (47%), Positives = 27/46 (58%), Gaps = 2/46 (4%) Query: 178 AGTPGYLSPEVLKKEPYGKP-VDIWACGVILYILLV-GYPPFWDED 221 AGT G+ +PEVL K P VDIW+ GVIL L +P F +D Sbjct: 289 AGTRGFRAPEVLFKCSSQSPKVDIWSAGVILLSFLTKRFPMFNSKD 334 >SPAC1805.05 |cki3||serine/threonine protein kinase Cki3|Schizosaccharomyces pombe|chr 1|||Manual Length = 439 Score = 40.3 bits (90), Expect = 6e-04 Identities = 39/155 (25%), Positives = 71/155 (45%), Gaps = 13/155 (8%) Query: 16 NYELKEELGKGAFSIVRRAVQKSTGYEFAAKIINTKKLSARDFQKLEREARICRKLQH-P 74 +Y + +++G+G+F ++ + V A K + K + +L E + L P Sbjct: 14 HYRVGKKIGEGSFGMLFQGVNLINNQPIALKFESRKS----EVPQLRDEYLTYKLLMGLP 69 Query: 75 NIVRLHDSIQEEHCHYLVFDLVTGG--ELFEDIVAREFYSEADASHCIQQILESVHHCHH 132 I ++ QE + LV DL+ +LF D R F S + +Q++ + H Sbjct: 70 GIPSVYYYGQEGMYNLLVMDLLGPSLEDLF-DYCGRRF-SPKTVAMIAKQMITRIQSVHE 127 Query: 133 NGVVHRDLKPENLLL---ASKAKGAAVKLADFGLA 164 ++RD+KP+N L+ SK + + DFG+A Sbjct: 128 RHFIYRDIKPDNFLIGFPGSKTEN-VIYAVDFGMA 161 >SPAC12B10.14c |ppk2||serine/threonine protein kinase Ppk2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 665 Score = 40.3 bits (90), Expect = 6e-04 Identities = 31/148 (20%), Positives = 66/148 (44%), Gaps = 6/148 (4%) Query: 71 LQHPNIVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHC 130 L H N++R ++S + + VF+ ++ + F+SE + + +I + Sbjct: 440 LSHKNLIRYNESFWYLNNIWSVFEYKDPSTKLSALIPKYFFSELNIASICYEISSGLAFL 499 Query: 131 HHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLK 190 H++G+ H +L E + L K + +K+ ++ + Q + P +L E Sbjct: 500 HNSGIAHHNLTTECIYL---TKSSCLKIGNYAFSSPYIERQTNRGAVSHVPDWLI-EKNY 555 Query: 191 KEPYGKPVDIWACGVILYILLVGYPPFW 218 KE + K D+ + G++ + G P F+ Sbjct: 556 KEGFMK--DVKSLGLVALEIFQGQPNFF 581 >SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizosaccharomyces pombe|chr 2|||Manual Length = 872 Score = 39.1 bits (87), Expect = 0.001 Identities = 50/190 (26%), Positives = 80/190 (42%), Gaps = 28/190 (14%) Query: 91 LVFDLVTGGELFEDIVAR--EFYSEADASHCIQQILESVHHCHH--NGVVHRDLKPENLL 146 L+ + GG L + + R SE + I I++ V H+ ++HRDLK EN+L Sbjct: 111 LLMEYCAGGGLIDFMNQRLQTRLSEHEVLKIISDIVQGVASLHYLRPPLIHRDLKVENVL 170 Query: 147 LASKAKGAAVKLADFGL----------AIEVQGDQQAWFGFAGTPGYLSPEVLKKEP--- 193 L+ KL DFG + E+Q +++ F T Y +PE++ Sbjct: 171 LSFN----TFKLCDFGSVTEPMHAAENSSEIQALEKSINTFT-TYQYRAPEMINLYSGLG 225 Query: 194 YGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDTVTPEAKSLIN 253 + D+WA GV+LY L PF + + Y P + + K++I Sbjct: 226 IDEKSDMWALGVLLYKLCYYTTPFETQGPNAILTA------SYSFPPFPPYSHSLKNVII 279 Query: 254 QMLTVNPSKR 263 +L NP R Sbjct: 280 ALLQPNPCLR 289 >SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 38.3 bits (85), Expect = 0.003 Identities = 48/166 (28%), Positives = 76/166 (45%), Gaps = 23/166 (13%) Query: 112 SEADASHCIQQILESVHHCHH--NGVVHRDLKPENLLLASKAKGAAVKLADFGLAIE-VQ 168 SE + + E+V H+ ++HRDLK EN+LLA+ + KL DFG A + Sbjct: 137 SEQEILKIASDVTEAVAVMHYLKPPLIHRDLKIENVLLAAP---NSYKLCDFGSACHPIP 193 Query: 169 GDQQAW--------FGFAGTPGYLSPEVLK-KEPYG--KPVDIWACGVILYILLVGYPPF 217 G + A T Y PE++ + +G + DIWA GV+ Y L PF Sbjct: 194 GAKTAAEAKQLEYDIEKFTTWQYRCPEMINVHKGFGIDEKSDIWALGVLFYKLCYYTTPF 253 Query: 218 WDEDQYRLYAQIKAGAYDYPSPEWDTVTPEAKSLINQMLTVNPSKR 263 +++ A I +Y +P+ + + K LI+ +L P +R Sbjct: 254 ----EHQGLAAIMNVSYAFPT--FPPYSDRLKRLISTLLQQYPWQR 293 >SPBP23A10.10 |ppk32||serine/threonine protein kinase Ppk32 |Schizosaccharomyces pombe|chr 2|||Manual Length = 749 Score = 35.5 bits (78), Expect = 0.018 Identities = 33/173 (19%), Positives = 79/173 (45%), Gaps = 14/173 (8%) Query: 113 EADASHCIQQILESVHHCHHNG-VVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQ 171 E + + QI++ + H + V+H +++P ++++ +K KL F + V+ + Sbjct: 147 EVEIQKGLLQIIDGLVFLHGSAKVIHYNIRPSSVVVDAKGDW---KLCGFSFSQSVESAR 203 Query: 172 QAWFGFA-GTPG-------YLSPEVLKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQY 223 + + G P +L+PE + E G D+++ G ++Y + + + + Sbjct: 204 YEFNDYDFGIPSSLQQSMDFLAPEYITHEIAGPESDVFSFGCLIYSIFNKNQSIINANNH 263 Query: 224 RLYAQIKAGAYDYPS--PEWDTVTPEAKSLINQMLTVNPSKRITASEALKHPW 274 L + + + + P+ + + KSL+ + L V+P +R + E + P+ Sbjct: 264 LLSYEKEITSLNSPTFIESKNLPSENLKSLLKETLAVDPKQRASMFELERSPY 316 >SPBC21C3.18 |spo4||serine/threonine protein kinase Spo4|Schizosaccharomyces pombe|chr 2|||Manual Length = 429 Score = 34.7 bits (76), Expect = 0.031 Identities = 20/46 (43%), Positives = 27/46 (58%), Gaps = 2/46 (4%) Query: 178 AGTPGYLSPEVLKK-EPYGKPVDIWACGVILYILLV-GYPPFWDED 221 AGT G+ +PEVL + + +D+W+ GVIL L YP F ED Sbjct: 262 AGTRGFRAPEVLFRCQNQTSSIDVWSVGVILLCFLTHRYPFFRCED 307 Score = 33.5 bits (73), Expect = 0.071 Identities = 22/106 (20%), Positives = 50/106 (47%), Gaps = 6/106 (5%) Query: 60 KLEREARICRKLQHPN-IVRLHDSIQEEHCHYLVFDLVTGGELFEDIVAREFYSEADASH 118 +++ E + +L+ + ++ + +++ + +V + E F D + YS + Sbjct: 105 RIQTELEMLHELRGSDCVLNMITAVRHQDQVLIVLPFIQHAE-FRDFYMK--YSLPEIGA 161 Query: 119 CIQQILESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLA 164 ++ +L+ + H G++HRD+KP N + + DFGLA Sbjct: 162 YLRDLLKGLAHIDAKGIIHRDIKPGNFAWNPYTQRGVI--LDFGLA 205 Score = 27.9 bits (59), Expect = 3.5 Identities = 11/25 (44%), Positives = 19/25 (76%) Query: 248 AKSLINQMLTVNPSKRITASEALKH 272 A L++++L ++PSKR+ A AL+H Sbjct: 376 AIDLLDKLLELHPSKRVKAKTALQH 400 >SPAC27E2.09 |mak2|phk1|histidine kinase Mak2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 2310 Score = 31.9 bits (69), Expect = 0.22 Identities = 21/90 (23%), Positives = 37/90 (41%), Gaps = 3/90 (3%) Query: 183 YLSPEVLKK--EPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPE 240 + SPE + P DI++ G++ Y++L P W R+ I + P Sbjct: 199 FFSPEQIGNVGRPLDSRSDIYSLGILFYVILTKQYP-WGGQSMRIVQSIHMRQFPSVLPR 257 Query: 241 WDTVTPEAKSLINQMLTVNPSKRITASEAL 270 P LI +M + + RI+++ L Sbjct: 258 RPDAFPALDQLIQKMTAKSMNSRISSATDL 287 >SPAC3H1.13 |ppk13||serine/threonine protein kinase Ppk13 |Schizosaccharomyces pombe|chr 1|||Manual Length = 344 Score = 30.7 bits (66), Expect = 0.50 Identities = 36/147 (24%), Positives = 57/147 (38%), Gaps = 14/147 (9%) Query: 136 VHRDLKPENLLLASKAKGAAVKLADFG----LAIEVQGDQQA-----WFGFAGTPGYLSP 186 +H D+KP+NLLL ++ + L DFG + I + +A T + +P Sbjct: 191 IHGDIKPDNLLLHENSR--EIVLTDFGSICLVPIFASNNSEAIAIQDKASENCTMPFRAP 248 Query: 187 E---VLKKEPYGKPVDIWACGVILYILLVGYPPFWDEDQYRLYAQIKAGAYDYPSPEWDT 243 E V + DIW+ G LY ++ PF E + Y P Sbjct: 249 ELFHVKAGSTITEKADIWSFGCTLYTIMFHASPFEREVSQGGSLALAVCNAQYSFPRKHP 308 Query: 244 VTPEAKSLINQMLTVNPSKRITASEAL 270 + ++ L P+KR +A E L Sbjct: 309 YSTLLCEIVEACLQREPNKRPSARELL 335 >SPBC530.14c |dsk1||SR protein-specific kinase Dsk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 544 Score = 30.7 bits (66), Expect = 0.50 Identities = 12/27 (44%), Positives = 20/27 (74%), Gaps = 1/27 (3%) Query: 122 QILESVHHCHHN-GVVHRDLKPENLLL 147 Q+L ++ + H G++H DLKPEN+L+ Sbjct: 196 QLLIALDYLHRECGIIHTDLKPENVLI 222 Score = 28.7 bits (61), Expect = 2.0 Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 3/58 (5%) Query: 156 VKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLKKEPYGKPVDIWACGVILYILLVG 213 VK+AD G A + + + T Y SPEV+ +G D W+ I++ LL G Sbjct: 356 VKIADLGNACWTR---KHFTNDVQTRQYRSPEVILGCRWGASADCWSFACIIFELLTG 410 >SPBC29A10.10c |||tRNA-splicing endonuclease positive effector |Schizosaccharomyces pombe|chr 2|||Manual Length = 1944 Score = 29.1 bits (62), Expect = 1.5 Identities = 13/33 (39%), Positives = 19/33 (57%) Query: 2 ANPNRESVSTRFSDNYELKEELGKGAFSIVRRA 34 +NP+ ++ ST D E +EE G FS+ R A Sbjct: 975 SNPDDKNTSTSDEDTSESEEESSNGLFSLAREA 1007 >SPAP27G11.07c |||serine/threonine protein kinase |Schizosaccharomyces pombe|chr 1|||Manual Length = 238 Score = 28.3 bits (60), Expect = 2.7 Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 1/44 (2%) Query: 120 IQQILESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGL 163 +++I V H N +VH DL N++L S + DFGL Sbjct: 129 MKRIGSEVAKMHKNDIVHGDLTTSNMMLESHNNPVPI-FIDFGL 171 >SPBC2D10.14c |myo51||myosin type V|Schizosaccharomyces pombe|chr 2|||Manual Length = 1471 Score = 27.5 bits (58), Expect = 4.7 Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 7/61 (11%) Query: 116 ASHCIQQILESVHHCHHNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDQQAWF 175 A+ I + L SV HNGVV R + EN +LA+ A FG A ++ D + F Sbjct: 168 AAKYIMRYLTSVQGVDHNGVVKRSV--ENQVLATNPIMEA-----FGNAKTIRNDNSSRF 220 Query: 176 G 176 G Sbjct: 221 G 221 >SPAC17C9.03 |tif471||translation initiation factor eIF4G |Schizosaccharomyces pombe|chr 1|||Manual Length = 1403 Score = 27.1 bits (57), Expect = 6.2 Identities = 11/41 (26%), Positives = 21/41 (51%) Query: 361 ISKEHDEEALTKADSFGKARGDSNASLRRAEVIKVTEVLID 401 + +E +E A KA+ GK D N ++ + + +E +D Sbjct: 689 VKRETEENAKRKAEEEGKREADKNPEIKSSAPLASSEANVD 729 Database: spombe Posted date: Oct 3, 2007 3:31 PM Number of letters in database: 2,362,478 Number of sequences in database: 5004 Lambda K H 0.319 0.134 0.405 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 2,266,619 Number of Sequences: 5004 Number of extensions: 92958 Number of successful extensions: 592 Number of sequences better than 10.0: 108 Number of HSP's better than 10.0 without gapping: 100 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 235 Number of HSP's gapped (non-prelim): 173 length of query: 510 length of database: 2,362,478 effective HSP length: 76 effective length of query: 434 effective length of database: 1,982,174 effective search space: 860263516 effective search space used: 860263516 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.8 bits) S2: 56 (26.6 bits)
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