Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000403-TA|BGIBMGA000403-PA|IPR001873|Na+ channel,
amiloride-sensitive
(749 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U38254-1|AAC50283.1| 638|Homo sapiens amiloride sensitive sodiu... 43 0.005
AK093239-1|BAC04105.1| 704|Homo sapiens protein ( Homo sapiens ... 42 0.006
BC125074-1|AAI25075.1| 638|Homo sapiens sodium channel, nonvolt... 41 0.018
BC036752-1|AAH36752.1| 560|Homo sapiens Similar to sodium chann... 41 0.018
AL162741-20|CAI23262.1| 638|Homo sapiens sodium channel, nonvol... 41 0.018
AL162741-19|CAI23261.1| 704|Homo sapiens sodium channel, nonvol... 41 0.018
AK131558-1|BAD18692.1| 669|Homo sapiens protein ( Homo sapiens ... 41 0.018
DQ898176-1|ABI64069.1| 704|Homo sapiens sodium channel nonvolta... 40 0.024
DQ898175-1|ABI64068.1| 638|Homo sapiens sodium channel nonvolta... 40 0.024
X87159-1|CAA60632.1| 640|Homo sapiens epithelial amiloride-sens... 36 0.52
L36593-1|AAA75459.1| 640|Homo sapiens epithelial sodium channel... 36 0.52
BC036352-1|AAH36352.2| 640|Homo sapiens sodium channel, nonvolt... 36 0.52
AJ005383-1|CAA06508.2| 640|Homo sapiens ENaCB, amiloride sensit... 36 0.52
AF057711-1|AAC62935.1| 531|Homo sapiens proton-gated cation cha... 33 2.8
AF195025-1|AAF19818.1| 549|Homo sapiens acid sensing ion channe... 33 3.7
AF195024-1|AAF19817.1| 543|Homo sapiens acid sensing ion channe... 33 3.7
AF095897-1|AAC64188.1| 531|Homo sapiens proton-gated cation cha... 33 3.7
AB209421-1|BAD92658.1| 446|Homo sapiens amiloride-sensitive cat... 33 3.7
AB010575-1|BAA25897.1| 532|Homo sapiens sodium channel protein. 33 3.7
X98654-1|CAA67224.1| 1244|Homo sapiens homologue of Drosphila re... 32 8.5
BC128577-1|AAI28578.1| 934|Homo sapiens RRBP1 protein protein. 32 8.5
BC108741-1|AAI08742.1| 394|Homo sapiens Unknown (protein for IM... 32 8.5
BC022230-1|AAH22230.1| 1243|Homo sapiens PITPNM1 protein protein. 32 8.5
BC009700-1|AAH09700.1| 304|Homo sapiens Unknown (protein for IM... 32 8.5
AY429102-1|AAR06909.1| 1243|Homo sapiens phosphatidylinositol tr... 32 8.5
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 32 8.5
AL132765-5|CAM20086.1| 300|Homo sapiens ribosome binding protei... 32 8.5
AL132765-4|CAH74034.1| 1410|Homo sapiens ribosome binding protei... 32 8.5
AF334584-1|AAK01444.1| 1244|Homo sapiens NIR2 protein. 32 8.5
AF007575-1|AAC25978.1| 560|Homo sapiens ES/130-related protein ... 32 8.5
AB037819-1|BAA92636.2| 1586|Homo sapiens KIAA1398 protein protein. 32 8.5
>U38254-1|AAC50283.1| 638|Homo sapiens amiloride sensitive sodium
channel delta subunit protein.
Length = 638
Score = 42.7 bits (96), Expect = 0.005
Identities = 64/306 (20%), Positives = 115/306 (37%), Gaps = 44/306 (14%)
Query: 463 FFLSCKWNGRPIDC-CKQFKPLA-TEYGTCFSINNKNVA-------GTQIPLVATSNRRI 513
F LSC ++G +DC +QF+ YG+C++++ A G + L +
Sbjct: 259 FVLSCSYDG--LDCQARQFRTFHHPTYGSCYTVDGVWTAQRPGITHGVGLVLRVEQQPHL 316
Query: 514 PGELEITTSQDYEAFIHSPEDVPFWNMEYDRRIRIVYGSQATVTFTIMDVVNEPEVSLIA 573
P ++T +H PF + G++AT++ + E EV +
Sbjct: 317 P---LLSTLAGIRVMVHGRNHTPFLG---HHSFSVRPGTEATIS------IREDEVHRLG 364
Query: 574 PETRQCRFSDETPE-NILAFKHYSYSVCITQCRIDAQLRMCNCTHHLSPIEFKDHVCDFE 632
C E E +L Y+ C+ C + C+C ++L P+ C
Sbjct: 365 SPYGHCTAGGEGVEVELLHNTSYTRQACLVSCFQQLMVETCSCGYYLHPLPAGAEYCSSA 424
Query: 633 GL----KCLTNNYKTLGKLKVPGTNEAGLVC-----------NCLPSCIEPDYNVIS-KK 676
C Y+ L ++P T+ C + PS + + + +
Sbjct: 425 RHPAWGHCFYRLYQDLETHRLPCTSRCPRPCRESAFKLSTGTSRWPSAKSAGWTLATLGE 484
Query: 677 LSEPEKFLRARPS----SFIMGSRPYQRVTRQVARTTLDLVVAMGNCFGLCFGGSLLSIA 732
P + R R S + + Y+ V + L+ AMG+ + L FG S+LS+
Sbjct: 485 QGLPHQSHRQRSSLAKINIVYQELNYRSVEEAPVYSVPQLLSAMGSLYSLWFGASVLSLL 544
Query: 733 EVVYYL 738
E++ L
Sbjct: 545 ELLELL 550
>AK093239-1|BAC04105.1| 704|Homo sapiens protein ( Homo sapiens
cDNA FLJ35920 fis, clone TESTI2010591, highly similar to
AMILORIDE-SENSITIVE SODIUM CHANNEL DELTA-SUBUNIT. ).
Length = 704
Score = 42.3 bits (95), Expect = 0.006
Identities = 65/306 (21%), Positives = 115/306 (37%), Gaps = 44/306 (14%)
Query: 463 FFLSCKWNGRPIDC-CKQFKPLA-TEYGTCFSINNKNVA-------GTQIPLVATSNRRI 513
F LSC ++G +DC +QF+ YG+C++++ A G + L +
Sbjct: 325 FVLSCSYDG--LDCQARQFRTFHYPTYGSCYTVDGVWTAQRPGITHGVGLVLRVEQQPHL 382
Query: 514 PGELEITTSQDYEAFIHSPEDVPFWNMEYDRRIRIVYGSQATVTFTIMDVVNEPEVSLIA 573
P ++T +H PF + G++AT++ + E EV +
Sbjct: 383 P---LLSTLAGIRVMVHGRNHTPFLG---HHSFSVRPGTEATIS------IREDEVHRLG 430
Query: 574 PETRQCRFSDETPE-NILAFKHYSYSVCITQCRIDAQLRMCNCTHHLSPIEFKDHVCDFE 632
C E E +L Y+ C+ C + C+C ++L P+ C
Sbjct: 431 SPYGHCTAGGEGVEVELLHNTSYTRQACLVSCFQQLMVETCSCGYYLHPLPAGAEYCSSA 490
Query: 633 GL----KCLTNNYKTLGKLKVPGTNEAGLVC-----------NCLPSCIEPDYNVIS-KK 676
CL Y+ L ++P T+ C + PS + + + +
Sbjct: 491 RHPAWGHCLYRLYQDLETHRLPCTSRCPRPCRESAFKLSTGTSRWPSAKSAGWTLATLGE 550
Query: 677 LSEPEKFLRARPS----SFIMGSRPYQRVTRQVARTTLDLVVAMGNCFGLCFGGSLLSIA 732
P + R R S + + Y+ V + L+ AMG+ L FG S+LS+
Sbjct: 551 QGLPHQSHRQRSSLAKINIVYQELNYRSVEEAPVYSVPQLLSAMGSLCSLWFGASVLSLL 610
Query: 733 EVVYYL 738
E++ L
Sbjct: 611 ELLELL 616
>BC125074-1|AAI25075.1| 638|Homo sapiens sodium channel,
nonvoltage-gated 1, delta protein.
Length = 638
Score = 40.7 bits (91), Expect = 0.018
Identities = 64/306 (20%), Positives = 114/306 (37%), Gaps = 44/306 (14%)
Query: 463 FFLSCKWNGRPIDC-CKQFKPLA-TEYGTCFSINNKNVA-------GTQIPLVATSNRRI 513
F LSC ++G +DC +QF+ YG+C++++ A G + L +
Sbjct: 259 FVLSCSYDG--LDCQARQFRTFHHPTYGSCYTVDGVWTAQRPGITHGVGLVLRVEQQPHL 316
Query: 514 PGELEITTSQDYEAFIHSPEDVPFWNMEYDRRIRIVYGSQATVTFTIMDVVNEPEVSLIA 573
P ++T +H PF + G++AT++ + E EV +
Sbjct: 317 P---LLSTLAGIRVMVHGRNHTPFLG---HHSFSVRPGTEATIS------IREDEVHRLG 364
Query: 574 PETRQCRFSDETPE-NILAFKHYSYSVCITQCRIDAQLRMCNCTHHLSPIEFKDHVCDFE 632
C E E +L Y+ C+ C + C+C ++L P+ C
Sbjct: 365 SPYGHCTAGGEGVEVELLHNTSYTRQACLVSCFQQLMVETCSCGYYLHPLPAGAEYCSSA 424
Query: 633 GL----KCLTNNYKTLGKLKVPGTNEAGLVC-----------NCLPSCIEPDYNVIS-KK 676
C Y+ L ++P T+ C + PS + + + +
Sbjct: 425 RHPAWGHCFYRLYQDLETHRLPCTSRCPRPCRESAFKLSTGTSRWPSAKSAGWTLATLGE 484
Query: 677 LSEPEKFLRARPS----SFIMGSRPYQRVTRQVARTTLDLVVAMGNCFGLCFGGSLLSIA 732
P + R R S + + Y+ V + L+ AMG+ L FG S+LS+
Sbjct: 485 QGLPHQSHRQRSSLAKINIVYQELNYRSVEEAPVYSVPQLLSAMGSLCSLWFGASVLSLL 544
Query: 733 EVVYYL 738
E++ L
Sbjct: 545 ELLELL 550
>BC036752-1|AAH36752.1| 560|Homo sapiens Similar to sodium channel,
nonvoltage-gated 1, delta protein.
Length = 560
Score = 40.7 bits (91), Expect = 0.018
Identities = 64/306 (20%), Positives = 114/306 (37%), Gaps = 44/306 (14%)
Query: 463 FFLSCKWNGRPIDC-CKQFKPLA-TEYGTCFSINNKNVA-------GTQIPLVATSNRRI 513
F LSC ++G +DC +QF+ YG+C++++ A G + L +
Sbjct: 259 FVLSCSYDG--LDCQARQFRTFHHPTYGSCYTVDGVWTAQRPGITHGVGLVLRVEQQPHL 316
Query: 514 PGELEITTSQDYEAFIHSPEDVPFWNMEYDRRIRIVYGSQATVTFTIMDVVNEPEVSLIA 573
P ++T +H PF + G++AT++ + E EV +
Sbjct: 317 P---LLSTLAGIRVMVHGRNHTPFLG---HHSFSVRPGTEATIS------IREDEVHRLG 364
Query: 574 PETRQCRFSDETPE-NILAFKHYSYSVCITQCRIDAQLRMCNCTHHLSPIEFKDHVCDFE 632
C E E +L Y+ C+ C + C+C ++L P+ C
Sbjct: 365 SPYGHCTAGGEGVEVQLLHNTSYTRQACLVSCFQQLMVETCSCGYYLHPLPAGAEYCSSA 424
Query: 633 GL----KCLTNNYKTLGKLKVPGTNEAGLVC-----------NCLPSCIEPDYNVIS-KK 676
C Y+ L ++P T+ C + PS + + + +
Sbjct: 425 RHPAWGHCFYRLYQDLETHRLPCTSRCPRPCRESAFKLSTGTSRWPSAKSAGWTLATLGE 484
Query: 677 LSEPEKFLRARPS----SFIMGSRPYQRVTRQVARTTLDLVVAMGNCFGLCFGGSLLSIA 732
P + R R S + + Y+ V + L+ AMG+ L FG S+LS+
Sbjct: 485 QGLPHQSHRQRSSLAKINIVYQELNYRSVEEAPVYSVPQLLSAMGSLCSLWFGASVLSLL 544
Query: 733 EVVYYL 738
E++ L
Sbjct: 545 ELLELL 550
>AL162741-20|CAI23262.1| 638|Homo sapiens sodium channel,
nonvoltage-gated 1, delta protein.
Length = 638
Score = 40.7 bits (91), Expect = 0.018
Identities = 64/306 (20%), Positives = 114/306 (37%), Gaps = 44/306 (14%)
Query: 463 FFLSCKWNGRPIDC-CKQFKPLA-TEYGTCFSINNKNVA-------GTQIPLVATSNRRI 513
F LSC ++G +DC +QF+ YG+C++++ A G + L +
Sbjct: 259 FVLSCSYDG--LDCQARQFRTFHHPTYGSCYTVDGVWTAQRPGITHGVGLVLRVEQQPHL 316
Query: 514 PGELEITTSQDYEAFIHSPEDVPFWNMEYDRRIRIVYGSQATVTFTIMDVVNEPEVSLIA 573
P ++T +H PF + G++AT++ + E EV +
Sbjct: 317 P---LLSTLAGIRVMVHGRNHTPFLG---HHSFSVRPGTEATIS------IREDEVHRLG 364
Query: 574 PETRQCRFSDETPE-NILAFKHYSYSVCITQCRIDAQLRMCNCTHHLSPIEFKDHVCDFE 632
C E E +L Y+ C+ C + C+C ++L P+ C
Sbjct: 365 SPYGHCTAGGEGVEVELLHNTSYTRQACLVSCFQQLMVETCSCGYYLHPLPAGAEYCSSA 424
Query: 633 GL----KCLTNNYKTLGKLKVPGTNEAGLVC-----------NCLPSCIEPDYNVIS-KK 676
C Y+ L ++P T+ C + PS + + + +
Sbjct: 425 RHPAWGHCFYRLYQDLETHRLPCTSRCPRPCRESAFKLSTGTSRWPSAKSAGWTLATLGE 484
Query: 677 LSEPEKFLRARPS----SFIMGSRPYQRVTRQVARTTLDLVVAMGNCFGLCFGGSLLSIA 732
P + R R S + + Y+ V + L+ AMG+ L FG S+LS+
Sbjct: 485 QGLPHQSHRQRSSLAKINIVYQELNYRSVEEAPVYSVPQLLSAMGSLCSLWFGASVLSLL 544
Query: 733 EVVYYL 738
E++ L
Sbjct: 545 ELLELL 550
>AL162741-19|CAI23261.1| 704|Homo sapiens sodium channel,
nonvoltage-gated 1, delta protein.
Length = 704
Score = 40.7 bits (91), Expect = 0.018
Identities = 64/306 (20%), Positives = 114/306 (37%), Gaps = 44/306 (14%)
Query: 463 FFLSCKWNGRPIDC-CKQFKPLA-TEYGTCFSINNKNVA-------GTQIPLVATSNRRI 513
F LSC ++G +DC +QF+ YG+C++++ A G + L +
Sbjct: 325 FVLSCSYDG--LDCQARQFRTFHHPTYGSCYTVDGVWTAQRPGITHGVGLVLRVEQQPHL 382
Query: 514 PGELEITTSQDYEAFIHSPEDVPFWNMEYDRRIRIVYGSQATVTFTIMDVVNEPEVSLIA 573
P ++T +H PF + G++AT++ + E EV +
Sbjct: 383 P---LLSTLAGIRVMVHGRNHTPFLG---HHSFSVRPGTEATIS------IREDEVHRLG 430
Query: 574 PETRQCRFSDETPE-NILAFKHYSYSVCITQCRIDAQLRMCNCTHHLSPIEFKDHVCDFE 632
C E E +L Y+ C+ C + C+C ++L P+ C
Sbjct: 431 SPYGHCTAGGEGVEVELLHNTSYTRQACLVSCFQQLMVETCSCGYYLHPLPAGAEYCSSA 490
Query: 633 GL----KCLTNNYKTLGKLKVPGTNEAGLVC-----------NCLPSCIEPDYNVIS-KK 676
C Y+ L ++P T+ C + PS + + + +
Sbjct: 491 RHPAWGHCFYRLYQDLETHRLPCTSRCPRPCRESAFKLSTGTSRWPSAKSAGWTLATLGE 550
Query: 677 LSEPEKFLRARPS----SFIMGSRPYQRVTRQVARTTLDLVVAMGNCFGLCFGGSLLSIA 732
P + R R S + + Y+ V + L+ AMG+ L FG S+LS+
Sbjct: 551 QGLPHQSHRQRSSLAKINIVYQELNYRSVEEAPVYSVPQLLSAMGSLCSLWFGASVLSLL 610
Query: 733 EVVYYL 738
E++ L
Sbjct: 611 ELLELL 616
>AK131558-1|BAD18692.1| 669|Homo sapiens protein ( Homo sapiens
cDNA FLJ16802 fis, clone TESTI4005158, highly similar
to Amiloride-sensitive sodium channel delta-subunit. ).
Length = 669
Score = 40.7 bits (91), Expect = 0.018
Identities = 64/306 (20%), Positives = 114/306 (37%), Gaps = 44/306 (14%)
Query: 463 FFLSCKWNGRPIDC-CKQFKPLA-TEYGTCFSINNKNVA-------GTQIPLVATSNRRI 513
F LSC ++G +DC +QF+ YG+C++++ A G + L +
Sbjct: 290 FVLSCSYDG--LDCQARQFRTFHHPTYGSCYTVDGVWTAQRPGITHGVGLVLRVEQQPHL 347
Query: 514 PGELEITTSQDYEAFIHSPEDVPFWNMEYDRRIRIVYGSQATVTFTIMDVVNEPEVSLIA 573
P ++T +H PF + G++AT++ + E EV +
Sbjct: 348 P---LLSTLAGIRVMVHGRNHTPFLG---HHSFSVRPGTEATIS------IREDEVHRLG 395
Query: 574 PETRQCRFSDETPE-NILAFKHYSYSVCITQCRIDAQLRMCNCTHHLSPIEFKDHVCDFE 632
C E E +L Y+ C+ C + C+C ++L P+ C
Sbjct: 396 SPYGHCTAGGEGVEVELLHNTSYTRQACLVSCFQQLMVETCSCGYYLHPLPAGAEYCSSA 455
Query: 633 GL----KCLTNNYKTLGKLKVPGTNEAGLVC-----------NCLPSCIEPDYNVIS-KK 676
C Y+ L ++P T+ C + PS + + + +
Sbjct: 456 RHPAWGHCFYRLYQDLETHRLPCTSRCPRPCRESAFKLSTGTSRWPSAKSAGWTLATLGE 515
Query: 677 LSEPEKFLRARPS----SFIMGSRPYQRVTRQVARTTLDLVVAMGNCFGLCFGGSLLSIA 732
P + R R S + + Y+ V + L+ AMG+ L FG S+LS+
Sbjct: 516 QGLPHQSHRQRSSLAKINIVYQELNYRSVEEAPVYSVPQLLSAMGSLCSLWFGASVLSLL 575
Query: 733 EVVYYL 738
E++ L
Sbjct: 576 ELLELL 581
>DQ898176-1|ABI64069.1| 704|Homo sapiens sodium channel
nonvoltage-gated 1 delta protein.
Length = 704
Score = 40.3 bits (90), Expect = 0.024
Identities = 64/306 (20%), Positives = 114/306 (37%), Gaps = 44/306 (14%)
Query: 463 FFLSCKWNGRPIDC-CKQFKPLA-TEYGTCFSINNKNVA-------GTQIPLVATSNRRI 513
F LSC ++G +DC +QF+ YG+C++++ A G + L +
Sbjct: 325 FALSCSYDG--LDCQARQFRTFHHPTYGSCYTVDGVWTAQRPGITHGVGLVLRVEQQPHL 382
Query: 514 PGELEITTSQDYEAFIHSPEDVPFWNMEYDRRIRIVYGSQATVTFTIMDVVNEPEVSLIA 573
P ++T +H PF + G++AT++ + E EV +
Sbjct: 383 P---LLSTLAGIRVMVHGRNHTPFLG---HHSFSVRPGTEATIS------IREDEVHRLG 430
Query: 574 PETRQCRFSDETPE-NILAFKHYSYSVCITQCRIDAQLRMCNCTHHLSPIEFKDHVCDFE 632
C E E +L Y+ C+ C + C+C ++L P+ C
Sbjct: 431 SPYGHCTAGGEGVEVELLHNTSYTRQACLVSCFQQLMVETCSCGYYLHPLPAGAEYCSSA 490
Query: 633 GL----KCLTNNYKTLGKLKVPGTNEAGLVC-----------NCLPSCIEPDYNVIS-KK 676
C Y+ L ++P T+ C + PS + + + +
Sbjct: 491 RHPAWGHCFYRLYQDLETHRLPCTSRCPRPCRESAFKLSTGTSRWPSAKSAGWTLATLGE 550
Query: 677 LSEPEKFLRARPS----SFIMGSRPYQRVTRQVARTTLDLVVAMGNCFGLCFGGSLLSIA 732
P + R R S + + Y+ V + L+ AMG+ L FG S+LS+
Sbjct: 551 QGLPHQSHRQRSSLAKINIVYQELNYRSVEEAPVYSVPQLLSAMGSLCSLWFGASVLSLL 610
Query: 733 EVVYYL 738
E++ L
Sbjct: 611 ELLELL 616
>DQ898175-1|ABI64068.1| 638|Homo sapiens sodium channel
nonvoltage-gated 1 delta protein.
Length = 638
Score = 40.3 bits (90), Expect = 0.024
Identities = 64/306 (20%), Positives = 114/306 (37%), Gaps = 44/306 (14%)
Query: 463 FFLSCKWNGRPIDC-CKQFKPLA-TEYGTCFSINNKNVA-------GTQIPLVATSNRRI 513
F LSC ++G +DC +QF+ YG+C++++ A G + L +
Sbjct: 259 FALSCSYDG--LDCQARQFRTFHHPTYGSCYTVDGVWTAQRPGITHGVGLVLRVEQQPHL 316
Query: 514 PGELEITTSQDYEAFIHSPEDVPFWNMEYDRRIRIVYGSQATVTFTIMDVVNEPEVSLIA 573
P ++T +H PF + G++AT++ + E EV +
Sbjct: 317 P---LLSTLAGIRVMVHGRNHTPFLG---HHSFSVRPGTEATIS------IREDEVHRLG 364
Query: 574 PETRQCRFSDETPE-NILAFKHYSYSVCITQCRIDAQLRMCNCTHHLSPIEFKDHVCDFE 632
C E E +L Y+ C+ C + C+C ++L P+ C
Sbjct: 365 SPYGHCTAGGEGVEVELLHNTSYTRQACLVSCFQQLMVETCSCGYYLHPLPAGAEYCSSA 424
Query: 633 GL----KCLTNNYKTLGKLKVPGTNEAGLVC-----------NCLPSCIEPDYNVIS-KK 676
C Y+ L ++P T+ C + PS + + + +
Sbjct: 425 RHPAWGHCFYRLYQDLETHRLPCTSRCPRPCRESAFKLSTGTSRWPSAKSAGWTLATLGE 484
Query: 677 LSEPEKFLRARPS----SFIMGSRPYQRVTRQVARTTLDLVVAMGNCFGLCFGGSLLSIA 732
P + R R S + + Y+ V + L+ AMG+ L FG S+LS+
Sbjct: 485 QGLPHQSHRQRSSLAKINIVYQELNYRSVEEAPVYSVPQLLSAMGSLCSLWFGASVLSLL 544
Query: 733 EVVYYL 738
E++ L
Sbjct: 545 ELLELL 550
>X87159-1|CAA60632.1| 640|Homo sapiens epithelial
amiloride-sensitive sodium channel, beta-subunit
protein.
Length = 640
Score = 35.9 bits (79), Expect = 0.52
Identities = 13/36 (36%), Positives = 19/36 (52%)
Query: 595 YSYSVCITQCRIDAQLRMCNCTHHLSPIEFKDHVCD 630
YS C+ C D +R CNC H+L P+ + C+
Sbjct: 381 YSIQACLRSCFQDHMIRNCNCGHYLYPLPRGEKYCN 416
>L36593-1|AAA75459.1| 640|Homo sapiens epithelial sodium channel
beta subunit protein.
Length = 640
Score = 35.9 bits (79), Expect = 0.52
Identities = 13/36 (36%), Positives = 19/36 (52%)
Query: 595 YSYSVCITQCRIDAQLRMCNCTHHLSPIEFKDHVCD 630
YS C+ C D +R CNC H+L P+ + C+
Sbjct: 381 YSIQACLRSCFQDHMIRNCNCGHYLYPLPRGEKYCN 416
>BC036352-1|AAH36352.2| 640|Homo sapiens sodium channel,
nonvoltage-gated 1, beta (Liddle syndrome) protein.
Length = 640
Score = 35.9 bits (79), Expect = 0.52
Identities = 13/36 (36%), Positives = 19/36 (52%)
Query: 595 YSYSVCITQCRIDAQLRMCNCTHHLSPIEFKDHVCD 630
YS C+ C D +R CNC H+L P+ + C+
Sbjct: 381 YSIQACLRSCFQDHMIRNCNCGHYLYPLPRGEKYCN 416
>AJ005383-1|CAA06508.2| 640|Homo sapiens ENaCB, amiloride sensitive
sodium channel beta subunit protein.
Length = 640
Score = 35.9 bits (79), Expect = 0.52
Identities = 13/36 (36%), Positives = 19/36 (52%)
Query: 595 YSYSVCITQCRIDAQLRMCNCTHHLSPIEFKDHVCD 630
YS C+ C D +R CNC H+L P+ + C+
Sbjct: 381 YSIQACLRSCFQDHMIRNCNCGHYLYPLPRGEKYCN 416
>AF057711-1|AAC62935.1| 531|Homo sapiens proton-gated cation
channel subunit protein.
Length = 531
Score = 33.5 bits (73), Expect = 2.8
Identities = 45/213 (21%), Positives = 80/213 (37%), Gaps = 14/213 (6%)
Query: 328 VHGPSFLARKDVHFVYKVIYFLIYVQIWIAAVATIRRYYNHYQENTIRFTTRTDYLEWNT 387
V GP L+ + + V+ + V ++ VA RYY + T + L
Sbjct: 32 VFGPGSLSLRRGMWAAAVV---LSVATFLYQVAERVRYYREFHHQTALDERESHRL---- 84
Query: 388 TFASVTVCEIANVEKIWMISNEVSNDNFEKFDRFIGDIAFFSGTCYTCLATCDFKPICSS 447
F +VT+C I + + + N++ + A F A F P +
Sbjct: 85 VFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPAEHAAFLRALGRPPAPPGFMPSPTF 144
Query: 448 DFTQTASMFRTPCKDFFLSCKWNGRPIDCCKQFKPLATEYGTCFSINNKNVAGTQIPLVA 507
D Q + D L C++ G+P + F + T G C++ N+ G + L+
Sbjct: 145 DMAQLYARAGHSLDDMLLDCRFRGQPCG-PENFTTIFTRMGKCYTFNS-GADGAE--LLT 200
Query: 508 TSNRRIPGELEITTSQDYEAFI---HSPEDVPF 537
T+ + L+I E ++ E+ PF
Sbjct: 201 TTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPF 233
Score = 32.7 bits (71), Expect = 4.9
Identities = 16/42 (38%), Positives = 25/42 (59%)
Query: 698 YQRVTRQVARTTLDLVVAMGNCFGLCFGGSLLSIAEVVYYLC 739
Y+ V ++ A +L+ +G GL G SLL+I E++ YLC
Sbjct: 420 YETVEQKKAYEMSELLGDIGGQMGLFIGASLLTILEILDYLC 461
>AF195025-1|AAF19818.1| 549|Homo sapiens acid sensing ion channel 3
splice variant c protein.
Length = 549
Score = 33.1 bits (72), Expect = 3.7
Identities = 45/213 (21%), Positives = 80/213 (37%), Gaps = 14/213 (6%)
Query: 328 VHGPSFLARKDVHFVYKVIYFLIYVQIWIAAVATIRRYYNHYQENTIRFTTRTDYLEWNT 387
V GP L+ + + V+ + V ++ VA RYY + T + L
Sbjct: 32 VFGPGSLSLRRGMWAAAVV---LSVATFLYQVAERVRYYREFHHQTALDERESHRL---- 84
Query: 388 TFASVTVCEIANVEKIWMISNEVSNDNFEKFDRFIGDIAFFSGTCYTCLATCDFKPICSS 447
F +VT+C I + + + N++ + A F A F P +
Sbjct: 85 IFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPAEHAAFLRALGRPPAPPGFMPSPTF 144
Query: 448 DFTQTASMFRTPCKDFFLSCKWNGRPIDCCKQFKPLATEYGTCFSINNKNVAGTQIPLVA 507
D Q + D L C++ G+P + F + T G C++ N+ G + L+
Sbjct: 145 DMAQLYARAGHSLDDMLLDCRFRGQPCG-PENFTTIFTRMGKCYTFNS-GADGAE--LLT 200
Query: 508 TSNRRIPGELEITTSQDYEAFI---HSPEDVPF 537
T+ + L+I E ++ E+ PF
Sbjct: 201 TTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPF 233
Score = 32.7 bits (71), Expect = 4.9
Identities = 16/42 (38%), Positives = 25/42 (59%)
Query: 698 YQRVTRQVARTTLDLVVAMGNCFGLCFGGSLLSIAEVVYYLC 739
Y+ V ++ A +L+ +G GL G SLL+I E++ YLC
Sbjct: 420 YETVEQKKAYEMSELLGDIGGQMGLFIGASLLTILEILDYLC 461
>AF195024-1|AAF19817.1| 543|Homo sapiens acid sensing ion channel 3
splice variant b protein.
Length = 543
Score = 33.1 bits (72), Expect = 3.7
Identities = 45/213 (21%), Positives = 80/213 (37%), Gaps = 14/213 (6%)
Query: 328 VHGPSFLARKDVHFVYKVIYFLIYVQIWIAAVATIRRYYNHYQENTIRFTTRTDYLEWNT 387
V GP L+ + + V+ + V ++ VA RYY + T + L
Sbjct: 32 VFGPGSLSLRRGMWAAAVV---LSVATFLYQVAERVRYYREFHHQTALDERESHRL---- 84
Query: 388 TFASVTVCEIANVEKIWMISNEVSNDNFEKFDRFIGDIAFFSGTCYTCLATCDFKPICSS 447
F +VT+C I + + + N++ + A F A F P +
Sbjct: 85 IFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPAEHAAFLRALGRPPAPPGFMPSPTF 144
Query: 448 DFTQTASMFRTPCKDFFLSCKWNGRPIDCCKQFKPLATEYGTCFSINNKNVAGTQIPLVA 507
D Q + D L C++ G+P + F + T G C++ N+ G + L+
Sbjct: 145 DMAQLYARAGHSLDDMLLDCRFRGQPCG-PENFTTIFTRMGKCYTFNS-GADGAE--LLT 200
Query: 508 TSNRRIPGELEITTSQDYEAFI---HSPEDVPF 537
T+ + L+I E ++ E+ PF
Sbjct: 201 TTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPF 233
Score = 32.7 bits (71), Expect = 4.9
Identities = 16/42 (38%), Positives = 25/42 (59%)
Query: 698 YQRVTRQVARTTLDLVVAMGNCFGLCFGGSLLSIAEVVYYLC 739
Y+ V ++ A +L+ +G GL G SLL+I E++ YLC
Sbjct: 420 YETVEQKKAYEMSELLGDIGGQMGLFIGASLLTILEILDYLC 461
>AF095897-1|AAC64188.1| 531|Homo sapiens proton-gated cation
channel ASIC3 protein.
Length = 531
Score = 33.1 bits (72), Expect = 3.7
Identities = 45/213 (21%), Positives = 80/213 (37%), Gaps = 14/213 (6%)
Query: 328 VHGPSFLARKDVHFVYKVIYFLIYVQIWIAAVATIRRYYNHYQENTIRFTTRTDYLEWNT 387
V GP L+ + + V+ + V ++ VA RYY + T + L
Sbjct: 32 VFGPGSLSLRRGMWAAAVV---LSVATFLYQVAERVRYYREFHHQTALDERESHRL---- 84
Query: 388 TFASVTVCEIANVEKIWMISNEVSNDNFEKFDRFIGDIAFFSGTCYTCLATCDFKPICSS 447
F +VT+C I + + + N++ + A F A F P +
Sbjct: 85 IFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPAEHAAFLRALGRPPAPPGFMPSPTF 144
Query: 448 DFTQTASMFRTPCKDFFLSCKWNGRPIDCCKQFKPLATEYGTCFSINNKNVAGTQIPLVA 507
D Q + D L C++ G+P + F + T G C++ N+ G + L+
Sbjct: 145 DMAQLYARAGHSLDDMLLDCRFRGQPCG-PENFTTIFTRMGKCYTFNS-GADGAE--LLT 200
Query: 508 TSNRRIPGELEITTSQDYEAFI---HSPEDVPF 537
T+ + L+I E ++ E+ PF
Sbjct: 201 TTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPF 233
Score = 32.7 bits (71), Expect = 4.9
Identities = 16/42 (38%), Positives = 25/42 (59%)
Query: 698 YQRVTRQVARTTLDLVVAMGNCFGLCFGGSLLSIAEVVYYLC 739
Y+ V ++ A +L+ +G GL G SLL+I E++ YLC
Sbjct: 420 YETVEQKKAYEMSELLGDIGGQMGLFIGASLLTILEILDYLC 461
>AB209421-1|BAD92658.1| 446|Homo sapiens amiloride-sensitive cation
channel 3 isoform c variant protein.
Length = 446
Score = 33.1 bits (72), Expect = 3.7
Identities = 45/213 (21%), Positives = 80/213 (37%), Gaps = 14/213 (6%)
Query: 328 VHGPSFLARKDVHFVYKVIYFLIYVQIWIAAVATIRRYYNHYQENTIRFTTRTDYLEWNT 387
V GP L+ + + V+ + V ++ VA RYY + T + L
Sbjct: 71 VFGPGSLSLRRGMWAAAVV---LSVATFLYQVAERVRYYREFHHQTALDERESHRL---- 123
Query: 388 TFASVTVCEIANVEKIWMISNEVSNDNFEKFDRFIGDIAFFSGTCYTCLATCDFKPICSS 447
F +VT+C I + + + N++ + A F A F P +
Sbjct: 124 IFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPAEHAAFLRALGRPPAPPGFMPSPTF 183
Query: 448 DFTQTASMFRTPCKDFFLSCKWNGRPIDCCKQFKPLATEYGTCFSINNKNVAGTQIPLVA 507
D Q + D L C++ G+P + F + T G C++ N+ G + L+
Sbjct: 184 DMAQLYARAGHSLDDMLLDCRFRGQPCG-PENFTTIFTRMGKCYTFNS-GADGAE--LLT 239
Query: 508 TSNRRIPGELEITTSQDYEAFI---HSPEDVPF 537
T+ + L+I E ++ E+ PF
Sbjct: 240 TTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPF 272
>AB010575-1|BAA25897.1| 532|Homo sapiens sodium channel protein.
Length = 532
Score = 33.1 bits (72), Expect = 3.7
Identities = 45/213 (21%), Positives = 80/213 (37%), Gaps = 14/213 (6%)
Query: 328 VHGPSFLARKDVHFVYKVIYFLIYVQIWIAAVATIRRYYNHYQENTIRFTTRTDYLEWNT 387
V GP L+ + + V+ + V ++ VA RYY + T + L
Sbjct: 32 VFGPGSLSLRRGMWAAAVV---LSVATFLYQVAERVRYYREFHHQTALDERESHRL---- 84
Query: 388 TFASVTVCEIANVEKIWMISNEVSNDNFEKFDRFIGDIAFFSGTCYTCLATCDFKPICSS 447
F +VT+C I + + + N++ + A F A F P +
Sbjct: 85 IFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPAEHAAFLRALGRPPAPPGFMPSPTF 144
Query: 448 DFTQTASMFRTPCKDFFLSCKWNGRPIDCCKQFKPLATEYGTCFSINNKNVAGTQIPLVA 507
D Q + D L C++ G+P + F + T G C++ N+ G + L+
Sbjct: 145 DMAQLYARAGHSLDDMLLDCRFRGQPCG-PENFTTIFTRMGKCYTFNS-GADGAE--LLT 200
Query: 508 TSNRRIPGELEITTSQDYEAFI---HSPEDVPF 537
T+ + L+I E ++ E+ PF
Sbjct: 201 TTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPF 233
Score = 32.7 bits (71), Expect = 4.9
Identities = 16/42 (38%), Positives = 25/42 (59%)
Query: 698 YQRVTRQVARTTLDLVVAMGNCFGLCFGGSLLSIAEVVYYLC 739
Y+ V ++ A +L+ +G GL G SLL+I E++ YLC
Sbjct: 421 YETVEQKKAYEMSELLGDIGGQMGLFIGASLLTILEILDYLC 462
>X98654-1|CAA67224.1| 1244|Homo sapiens homologue of Drosphila
retinal degeneration B gene protein.
Length = 1244
Score = 31.9 bits (69), Expect = 8.5
Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 3/53 (5%)
Query: 488 GTCFSINNKNVAGTQIPLVATSNRRIPGELEIT---TSQDYEAFIHSPEDVPF 537
G S + ++ +PL+ATS+ R G + T+Q Y AF+ SPE F
Sbjct: 503 GDSLSRSQDHIPLAALPLLATSSSRYQGAVATVIARTNQAYSAFLRSPEGAGF 555
>BC128577-1|AAI28578.1| 934|Homo sapiens RRBP1 protein protein.
Length = 934
Score = 31.9 bits (69), Expect = 8.5
Identities = 15/38 (39%), Positives = 19/38 (50%)
Query: 194 GNSTRTSTPQRSSLEGTNSKSKKVSFFRRLGRSKDSTP 231
GN+ T T Q EGT ++SKK GR + TP
Sbjct: 11 GNTPATGTTQGKKAEGTQNQSKKAEGAPNQGRKAEGTP 48
>BC108741-1|AAI08742.1| 394|Homo sapiens Unknown (protein for
IMAGE:6156239) protein.
Length = 394
Score = 31.9 bits (69), Expect = 8.5
Identities = 15/38 (39%), Positives = 19/38 (50%)
Query: 194 GNSTRTSTPQRSSLEGTNSKSKKVSFFRRLGRSKDSTP 231
GN+ T T Q EGT ++SKK GR + TP
Sbjct: 189 GNTPATGTTQGKKAEGTQNQSKKAEGAPNQGRKAEGTP 226
>BC022230-1|AAH22230.1| 1243|Homo sapiens PITPNM1 protein protein.
Length = 1243
Score = 31.9 bits (69), Expect = 8.5
Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 3/53 (5%)
Query: 488 GTCFSINNKNVAGTQIPLVATSNRRIPGELEIT---TSQDYEAFIHSPEDVPF 537
G S + ++ +PL+ATS+ R G + T+Q Y AF+ SPE F
Sbjct: 503 GDSLSRSQDHIPLAALPLLATSSSRYQGAVATVIARTNQAYSAFLRSPEGAGF 555
>BC009700-1|AAH09700.1| 304|Homo sapiens Unknown (protein for
IMAGE:3900104) protein.
Length = 304
Score = 31.9 bits (69), Expect = 8.5
Identities = 15/38 (39%), Positives = 19/38 (50%)
Query: 194 GNSTRTSTPQRSSLEGTNSKSKKVSFFRRLGRSKDSTP 231
GN+ T T Q EGT ++SKK GR + TP
Sbjct: 189 GNTPATGTTQGKKAEGTQNQSKKAEGAPNQGRKAEGTP 226
>AY429102-1|AAR06909.1| 1243|Homo sapiens phosphatidylinositol
transfer protein membrane-associated 1 protein.
Length = 1243
Score = 31.9 bits (69), Expect = 8.5
Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 3/53 (5%)
Query: 488 GTCFSINNKNVAGTQIPLVATSNRRIPGELEIT---TSQDYEAFIHSPEDVPF 537
G S + ++ +PL+ATS+ R G + T+Q Y AF+ SPE F
Sbjct: 503 GDSLSRSQDHIPLAALPLLATSSSRYQGAVATVIARTNQAYSAFLRSPEGAGF 555
>AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608
protein.
Length = 2623
Score = 31.9 bits (69), Expect = 8.5
Identities = 13/35 (37%), Positives = 21/35 (60%), Gaps = 2/35 (5%)
Query: 374 IRFTTRTDYLEWNTTFASVTVCEI--ANVEKIWMI 406
I FT DY+ NT+F++ VC I +++ +W I
Sbjct: 343 IAFTEENDYIVLNTSFSTFLVCNIDYGHIQPVWQI 377
>AL132765-5|CAM20086.1| 300|Homo sapiens ribosome binding protein 1
homolog 180kDa (dog) protein.
Length = 300
Score = 31.9 bits (69), Expect = 8.5
Identities = 15/38 (39%), Positives = 19/38 (50%)
Query: 194 GNSTRTSTPQRSSLEGTNSKSKKVSFFRRLGRSKDSTP 231
GN+ T T Q EGT ++SKK GR + TP
Sbjct: 189 GNTPATGTTQGKKAEGTQNQSKKAEGAPNQGRKAEGTP 226
>AL132765-4|CAH74034.1| 1410|Homo sapiens ribosome binding protein 1
homolog 180kDa (dog) protein.
Length = 1410
Score = 31.9 bits (69), Expect = 8.5
Identities = 15/38 (39%), Positives = 19/38 (50%)
Query: 194 GNSTRTSTPQRSSLEGTNSKSKKVSFFRRLGRSKDSTP 231
GN+ T T Q EGT ++SKK GR + TP
Sbjct: 189 GNTPATGTTQGKKAEGTQNQSKKAEGAPNQGRKAEGTP 226
>AF334584-1|AAK01444.1| 1244|Homo sapiens NIR2 protein.
Length = 1244
Score = 31.9 bits (69), Expect = 8.5
Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 3/53 (5%)
Query: 488 GTCFSINNKNVAGTQIPLVATSNRRIPGELEIT---TSQDYEAFIHSPEDVPF 537
G S + ++ +PL+ATS+ R G + T+Q Y AF+ SPE F
Sbjct: 503 GDSLSRSQDHIPLAALPLLATSSSRYQGAVATVIARTNQAYSAFLRSPEGAGF 555
>AF007575-1|AAC25978.1| 560|Homo sapiens ES/130-related protein
protein.
Length = 560
Score = 31.9 bits (69), Expect = 8.5
Identities = 15/38 (39%), Positives = 19/38 (50%)
Query: 194 GNSTRTSTPQRSSLEGTNSKSKKVSFFRRLGRSKDSTP 231
GN+ T T Q EGT ++SKK GR + TP
Sbjct: 13 GNTPATGTTQGKKAEGTQNQSKKAEGAPNQGRKAEGTP 50
>AB037819-1|BAA92636.2| 1586|Homo sapiens KIAA1398 protein protein.
Length = 1586
Score = 31.9 bits (69), Expect = 8.5
Identities = 15/38 (39%), Positives = 19/38 (50%)
Query: 194 GNSTRTSTPQRSSLEGTNSKSKKVSFFRRLGRSKDSTP 231
GN+ T T Q EGT ++SKK GR + TP
Sbjct: 215 GNTPATGTTQGKKAEGTQNQSKKAEGAPNQGRKAEGTP 252
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.323 0.136 0.423
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 105,276,244
Number of Sequences: 224733
Number of extensions: 4423511
Number of successful extensions: 7950
Number of sequences better than 10.0: 31
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 7906
Number of HSP's gapped (non-prelim): 64
length of query: 749
length of database: 73,234,838
effective HSP length: 96
effective length of query: 653
effective length of database: 51,660,470
effective search space: 33734286910
effective search space used: 33734286910
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 69 (31.9 bits)
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