Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000390-TA|BGIBMGA000390-PA|IPR000728|AIR synthase
related protein, IPR010918|AIR synthase related protein, C-terminal,
IPR010073|Phosphoribosylformylglycinamidine synthase, eukaryotes and
proteobacteria
(1340 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P35421 Cluster: Phosphoribosylformylglycinamidine synth... 1360 0.0
UniRef50_O15067 Cluster: Phosphoribosylformylglycinamidine synth... 1242 0.0
UniRef50_Q9M8D3 Cluster: Probable phosphoribosylformylglycinamid... 1176 0.0
UniRef50_Q54JC8 Cluster: Phosphoribosylformylglycinamide synthas... 1163 0.0
UniRef50_Q19311 Cluster: Probable phosphoribosylformylglycinamid... 1035 0.0
UniRef50_Q6AQE0 Cluster: Probable phosphoribosylformylglycinamid... 986 0.0
UniRef50_Q60B11 Cluster: Phosphoribosylformylglycinamidine synth... 665 0.0
UniRef50_Q87RW0 Cluster: Phosphoribosylformylglycinamidine synth... 663 0.0
UniRef50_Q6LU24 Cluster: Phosphoribosylformylglycinamidine synth... 662 0.0
UniRef50_A6EP05 Cluster: Phosphoribosylformylglycinamidine synth... 656 0.0
UniRef50_Q5QWY0 Cluster: Phosphoribosylformylglycinamidine synth... 654 0.0
UniRef50_A5WCV9 Cluster: Phosphoribosylformylglycinamidine synth... 645 0.0
UniRef50_Q7MXB0 Cluster: Phosphoribosylformylglycinamidine synth... 643 0.0
UniRef50_P38972 Cluster: Phosphoribosylformylglycinamidine synth... 636 e-180
UniRef50_Q9JXK5 Cluster: Phosphoribosylformylglycinamidine synth... 634 e-180
UniRef50_Q2UAH0 Cluster: Phosphoribosylformylglycinamidine synth... 592 e-167
UniRef50_Q8XYN6 Cluster: Phosphoribosylformylglycinamidine synth... 576 e-162
UniRef50_Q016J3 Cluster: Putative formylglycineamide ribotide am... 575 e-162
UniRef50_Q12AE0 Cluster: Phosphoribosylformylglycinamidine synth... 566 e-159
UniRef50_Q8PCQ7 Cluster: Phosphoribosylformylglycinamidine synth... 544 e-153
UniRef50_Q9PDF6 Cluster: Phosphoribosylformylglycinamidine synth... 541 e-152
UniRef50_Q2GZN5 Cluster: Putative uncharacterized protein; n=1; ... 347 2e-93
UniRef50_A7LBA5 Cluster: Truncated formylglycineamide ribonucleo... 193 3e-47
UniRef50_A5D2D1 Cluster: Phosphoribosylformylglycinamidine (FGAM... 175 9e-42
UniRef50_P03179 Cluster: Probable membrane antigen P140; n=7; Ly... 171 8e-41
UniRef50_Q8BEM8 Cluster: ORF65; n=1; Callitrichine herpesvirus 3... 163 4e-38
UniRef50_Q1VJH3 Cluster: Phosphoribosylformylglycinamidine synth... 159 6e-37
UniRef50_Q0PQQ1 Cluster: Phosphoribosylformylglycinamidine synth... 157 1e-36
UniRef50_Q7URX8 Cluster: Phosphoribosylformylglycinamidine synth... 151 2e-34
UniRef50_Q66609 Cluster: Tegument protein; n=1; Equid herpesviru... 149 5e-34
UniRef50_Q73N76 Cluster: Phosphoribosylformylglycinamidine synth... 146 4e-33
UniRef50_Q3ZZB9 Cluster: Phosphoribosylformylglycinamidine synth... 146 5e-33
UniRef50_Q53CQ9 Cluster: JM161; n=3; Cercopithecine herpesvirus ... 145 6e-33
UniRef50_A5D2D2 Cluster: Phosphoribosylformylglycinamidine (FGAM... 142 6e-32
UniRef50_Q99D25 Cluster: V-FGAM-synthase; n=1; Bovine herpesviru... 141 1e-31
UniRef50_Q99CW7 Cluster: Tegument protein/v-FGAM-synthetase; n=3... 138 1e-30
UniRef50_A1BM63 Cluster: Phosphoribosylformylglycinamidine synth... 138 1e-30
UniRef50_Q1Q6R2 Cluster: Similar to phosphoribosylformylglycinam... 136 5e-30
UniRef50_O23992 Cluster: Expressed sequence tag; n=3; Eukaryota|... 132 6e-29
UniRef50_Q98145 Cluster: Membrane antigen p140 homolog; n=310; H... 132 8e-29
UniRef50_Q6M0U0 Cluster: Phosphoribosylformylglycinamidine synth... 128 1e-27
UniRef50_Q97C36 Cluster: Phosphoribosylformylglycinamidine synth... 127 2e-27
UniRef50_A5UUD1 Cluster: Phosphoribosylformylglycinamidine synth... 126 4e-27
UniRef50_Q2FPM9 Cluster: Phosphoribosylformylglycinamidine synth... 124 2e-26
UniRef50_A5UWJ5 Cluster: Phosphoribosylformylglycinamidine synth... 121 2e-25
UniRef50_O41976 Cluster: Tegument protein/FGARATc; n=1; Murid he... 118 1e-24
UniRef50_A6PUZ9 Cluster: Phosphoribosylformylglycinamidine synth... 118 1e-24
UniRef50_Q3Z9H5 Cluster: Phosphoribosylformylglycinamidine synth... 118 1e-24
UniRef50_A6G365 Cluster: Phosphoribosylformylglycinamidine synth... 113 4e-23
UniRef50_Q5FDA5 Cluster: Phosphoribosylformylglycinamidine synth... 112 7e-23
UniRef50_Q2Q0E4 Cluster: Phosphoribosylformylglycinamidine synth... 111 1e-22
UniRef50_Q73MV2 Cluster: Phosphoribosylformylglycinamidine synth... 111 1e-22
UniRef50_Q1FHW3 Cluster: Phosphoribosylformylglycinamidine synth... 110 3e-22
UniRef50_P11282 Cluster: Probable membrane antigen 75; n=3; Herp... 109 4e-22
UniRef50_Q59042 Cluster: Phosphoribosylformylglycinamidine synth... 109 7e-22
UniRef50_Q2VSN3 Cluster: ORF3; n=3; Rhadinovirus|Rep: ORF3 - Ovi... 106 4e-21
UniRef50_Q7UMS8 Cluster: Phosphoribosylformylglycinamidine synth... 105 8e-21
UniRef50_O29008 Cluster: Phosphoribosylformylglycinamidine synth... 105 1e-20
UniRef50_Q6MIZ1 Cluster: Phosphoribosylformylglycinamidine synth... 104 2e-20
UniRef50_Q66675 Cluster: Tegument protein; n=1; Equid herpesviru... 103 3e-20
UniRef50_Q2Q0E5 Cluster: Phosphoribosylformylglycinamidine synth... 102 6e-20
UniRef50_Q74CN8 Cluster: Phosphoribosylformylglycinamidine synth... 101 1e-19
UniRef50_A0B5C6 Cluster: Phosphoribosylformylglycinamidine synth... 101 1e-19
UniRef50_Q74CN9 Cluster: Phosphoribosylformylglycinamidine synth... 99 7e-19
UniRef50_Q6MIZ0 Cluster: Phosphoribosylformylglycinamidine synth... 97 2e-18
UniRef50_A6C4F9 Cluster: Phosphoribosylformylglycinamidine synth... 95 9e-18
UniRef50_O67190 Cluster: Phosphoribosylformylglycinamidine synth... 95 9e-18
UniRef50_Q8B409 Cluster: Tegument protein/v-FGAM-synthase; n=4; ... 95 1e-17
UniRef50_Q3DJT6 Cluster: Phosphoribosylformylglycinamidine synth... 94 2e-17
UniRef50_A1IAB2 Cluster: Phosphoribosylformylglycinamidine synth... 94 2e-17
UniRef50_A7PSW6 Cluster: Chromosome chr8 scaffold_29, whole geno... 93 6e-17
UniRef50_Q9HNU2 Cluster: Phosphoribosylformylglycinamidine synth... 89 8e-16
UniRef50_Q5GT14 Cluster: Phosphoribosylformylglycinamidine (FGAM... 88 1e-15
UniRef50_Q6M0T9 Cluster: Phosphoribosylformylglycinamidine synth... 88 2e-15
UniRef50_Q2GDW3 Cluster: Putative phosphoribosylformylglycinamid... 87 2e-15
UniRef50_A0LFD0 Cluster: Phosphoribosylformylglycinamidine synth... 84 3e-14
UniRef50_A1UT45 Cluster: Phosphoribosylformylglycinamidine synth... 83 5e-14
UniRef50_O41977 Cluster: Tegument protein/FGARAT; n=1; Murid her... 82 9e-14
UniRef50_Q5ZUW6 Cluster: Phosphoribosylformylglycinamidine synth... 82 9e-14
UniRef50_A5BZD1 Cluster: Putative uncharacterized protein; n=1; ... 82 9e-14
UniRef50_A6G366 Cluster: Phosphoribosylformylglycinamidine synth... 81 3e-13
UniRef50_Q2NF29 Cluster: Phosphoribosylformylglycinamidine synth... 80 5e-13
UniRef50_Q8ZZJ7 Cluster: Phosphoribosylformylglycinamidine synth... 79 8e-13
UniRef50_O67691 Cluster: Phosphoribosylformylglycinamidine synth... 79 8e-13
UniRef50_A5EXN9 Cluster: Phosphoribosylformylglycinamidine synth... 78 1e-12
UniRef50_O59619 Cluster: Phosphoribosylformylglycinamidine synth... 78 2e-12
UniRef50_Q67KF7 Cluster: Phosphoribosylformylglycinamidine synth... 77 3e-12
UniRef50_Q01000 Cluster: Probable membrane antigen 3; n=4; Herpe... 77 4e-12
UniRef50_Q9HJA4 Cluster: Phosphoribosylformylglycinamidine synth... 76 8e-12
UniRef50_Q6N376 Cluster: Phosphoribosylformylglycinamidine synth... 74 3e-11
UniRef50_Q7NL01 Cluster: Phosphoribosylformylglycinamidine synth... 74 3e-11
UniRef50_Q4FLJ5 Cluster: Phosphoribosylformylglycinamidine synth... 73 4e-11
UniRef50_Q11IV0 Cluster: Phosphoribosylformylglycinamidine synth... 73 5e-11
UniRef50_Q9RXT3 Cluster: Phosphoribosylformylglycinamidine synth... 71 2e-10
UniRef50_Q8TY09 Cluster: Phosphoribosylformylglycinamidine synth... 71 3e-10
UniRef50_UPI00015BB1F1 Cluster: phosphoribosylformylglycinamidin... 70 5e-10
UniRef50_Q58660 Cluster: Phosphoribosylformylglycinamidine synth... 69 7e-10
UniRef50_Q7VC88 Cluster: Phosphoribosylformylglycinamidine synth... 69 9e-10
UniRef50_Q9KF57 Cluster: Phosphoribosylformylglycinamidine synth... 69 9e-10
UniRef50_O41978 Cluster: Tegument protein/FGARAT; n=2; Murid her... 67 3e-09
UniRef50_A7D7A8 Cluster: Phosphoribosylformylglycinamidine synth... 67 4e-09
UniRef50_Q2GCW2 Cluster: Putative phosphoribosylformylglycinamid... 66 5e-09
UniRef50_Q3AYR1 Cluster: Phosphoribosylformylglycinamidine synth... 66 6e-09
UniRef50_Q9PHZ7 Cluster: Phosphoribosylformylglycinamidine synth... 65 1e-08
UniRef50_Q72IH7 Cluster: Phosphoribosylformylglycinamidine synth... 65 1e-08
UniRef50_O28339 Cluster: Phosphoribosylformylglycinamidine synth... 63 6e-08
UniRef50_Q5Z2C3 Cluster: Phosphoribosylformylglycinamidine synth... 62 1e-07
UniRef50_Q2J4N0 Cluster: Phosphoribosylformylglycinamidine synth... 60 3e-07
UniRef50_Q5V2D3 Cluster: Phosphoribosylformylglycinamidine synth... 60 4e-07
UniRef50_UPI00015BB107 Cluster: phosphoribosylformylglycinamidin... 59 9e-07
UniRef50_Q9UXW6 Cluster: Phosphoribosylformylglycinamidine synth... 59 9e-07
UniRef50_Q8JNB5 Cluster: BNRF1-like protein; n=1; Mustelid herpe... 57 4e-06
UniRef50_Q8F0I2 Cluster: Phosphoribosylformylglycinamidine synth... 57 4e-06
UniRef50_UPI0000383935 Cluster: COG0047: Phosphoribosylformylgly... 56 7e-06
UniRef50_A7HM11 Cluster: Phosphoribosylformylglycinamidine synth... 56 9e-06
UniRef50_A3H6X8 Cluster: Phosphoribosylformylglycinamidine synth... 56 9e-06
UniRef50_Q8PYK1 Cluster: Phosphoribosylformylglycinamidine synth... 55 1e-05
UniRef50_A7DSW4 Cluster: Phosphoribosylformylglycinamidine synth... 54 3e-05
UniRef50_Q8KD17 Cluster: Phosphoribosylformylglycinamidine synth... 54 4e-05
UniRef50_Q4J8F8 Cluster: Phosphoribosylformylglycinamidine synth... 52 8e-05
UniRef50_Q5WW17 Cluster: Phosphoribosylformylglycinamidine synth... 52 1e-04
UniRef50_A3EVN1 Cluster: Phosphoribosylformylglycinamidine synth... 51 2e-04
UniRef50_A3CWL7 Cluster: Phosphoribosylformylglycinamidine (FGAM... 50 4e-04
UniRef50_Q7VF52 Cluster: Phosphoribosylformylglycinamidine synth... 50 4e-04
UniRef50_A4M897 Cluster: Phosphoribosylformylglycinamidine synth... 50 6e-04
UniRef50_Q9X0X3 Cluster: Phosphoribosylformylglycinamidine synth... 48 0.001
UniRef50_Q2NEB6 Cluster: Phosphoribosylformylglycinamidine synth... 46 0.005
UniRef50_Q7VEK9 Cluster: Phosphoribosylformylglycinamidine synth... 46 0.007
UniRef50_A0RYV3 Cluster: Phosphoribosylformylglycinamidine (FGAM... 45 0.012
UniRef50_Q8DIA7 Cluster: Phosphoribosylformylglycinamidine synth... 44 0.037
UniRef50_Q67KF8 Cluster: Phosphoribosylformylglycinamidine synth... 44 0.037
UniRef50_Q57DR8 Cluster: Phosphoribosylformylglycinamidine synth... 44 0.037
UniRef50_A3VSU9 Cluster: Phosphoribosylformylglycinamidine synth... 43 0.050
UniRef50_A5NUY4 Cluster: Phosphoribosylformylglycinamidine synth... 42 0.11
UniRef50_A3EVN2 Cluster: Phosphoribosylformylglycinamidine synth... 42 0.15
UniRef50_Q8FMM3 Cluster: Phosphoribosylformylglycinamidine synth... 42 0.15
UniRef50_Q1VJ60 Cluster: Phosphoribosylformylglycinamidine synth... 41 0.26
UniRef50_A0B5C7 Cluster: Phosphoribosylformylglycinamidine synth... 41 0.26
UniRef50_Q2J4Z5 Cluster: DEAD/DEAH box helicase-like; n=3; Frank... 39 1.1
UniRef50_Q0LR46 Cluster: Putative uncharacterized protein; n=1; ... 38 2.5
UniRef50_A7GWE3 Cluster: Transcription termination factor; n=1; ... 38 2.5
UniRef50_UPI0001509D30 Cluster: hypothetical protein TTHERM_0065... 37 3.3
UniRef50_Q9RXF2 Cluster: Competence protein ComEC/Rec2-related p... 37 3.3
UniRef50_Q2SQ63 Cluster: Uncharacterized protein conserved in ba... 37 4.3
UniRef50_A7DQ22 Cluster: Putative uncharacterized protein precur... 37 4.3
UniRef50_Q97J06 Cluster: Predicted dehydrogenase; n=1; Clostridi... 36 5.7
UniRef50_A1FJG1 Cluster: Sodium/hydrogen exchanger precursor; n=... 36 5.7
UniRef50_A3TL52 Cluster: VCBS; n=1; Janibacter sp. HTCC2649|Rep:... 36 7.5
UniRef50_A5AHS1 Cluster: Putative uncharacterized protein; n=2; ... 36 7.5
UniRef50_Q8S8A7 Cluster: Predicted protein; n=1; Arabidopsis tha... 36 9.9
UniRef50_A5DJ97 Cluster: Putative uncharacterized protein; n=1; ... 36 9.9
UniRef50_A3CSW3 Cluster: Cobalt transport protein CbiN precursor... 36 9.9
>UniRef50_P35421 Cluster: Phosphoribosylformylglycinamidine synthase;
n=7; Fungi/Metazoa group|Rep:
Phosphoribosylformylglycinamidine synthase - Drosophila
melanogaster (Fruit fly)
Length = 1354
Score = 1360 bits (3369), Expect = 0.0
Identities = 695/1364 (50%), Positives = 906/1364 (66%), Gaps = 40/1364 (2%)
Query: 1 MSIVRFFSTEAFSLHKTNEILQKLKFVDSDIKDLSTELCYHVELAEGCEYLNINQIKVLK 60
M I+R++ +A S + +L++L+ D + + E CYH+E + E+ ++ ++L
Sbjct: 1 MVILRYYDVQAHSAAEEESVLRRLREEDGAVVSVRMERCYHLEYSAQAEH-SLALDELLV 59
Query: 61 WLLSSPLQP-QAVRNETIFKSNDNSQLLIEIGPRFNFSTADSSNSVQICESVGLRDVVRL 119
WL+ PL Q++ + +S +SQLL+EIGPRFNFST S+N V I +++G +V R+
Sbjct: 60 WLVKQPLSKGQSLSRQPALQSTGSSQLLLEIGPRFNFSTPYSTNCVNIFQNLGYSEVRRM 119
Query: 120 EVSTRYLITFGKQKNVTEKHFENLAAVLHDRMTQCVYTKDNLPRKSFNEGLPKDLEPWFV 179
E STRYL+TFG+ E +L DRMTQC+YT++N P+ SF+E LP+ W
Sbjct: 120 ETSTRYLVTFGEGSKAPEA--ARFVPLLGDRMTQCLYTEENTPKASFDEQLPERQANWHF 177
Query: 180 VPLQEQGISAMRKVNDKLGLAFDTWDMEFYMDLFVNKLKRDPTSVELFDLAQSNSEHSRH 239
VP+ E+G +A+ ++N +LGLAF+ +D+++Y DLF +L R+PT+VELFD AQSNSEHSRH
Sbjct: 178 VPVLEEGRAALERINQELGLAFNDYDLDYYHDLFAKELGRNPTTVELFDCAQSNSEHSRH 237
Query: 240 WFFKGKLVLDGKEINESLIDMVASTQKTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRGP 299
WFF+G++V+DG E +SLI M+ TQ +N NN IKF DNSSA+ GF H + P++V P
Sbjct: 238 WFFRGRMVIDGVEQPKSLIRMIMDTQAHTNPNNTIKFSDNSSAMVGFDHQTIVPSSVVAP 297
Query: 300 SQVIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSV 359
V + +SD+IFTAETHNMPTAVAPFSGATTGTGGR+RDVQGVGRGG +AGTAGY V
Sbjct: 298 GAVRLQSVQSDLIFTAETHNMPTAVAPFSGATTGTGGRLRDVQGVGRGGVPIAGTAGYCV 357
Query: 360 GNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKN 419
G LHIPGY P+E ++YP+ FA PLQ++IEASNGASDYGNKFGEPVISGF SYGL +
Sbjct: 358 GALHIPGYKQPYEPLDFKYPATFAPPLQVLIEASNGASDYGNKFGEPVISGFALSYGLNS 417
Query: 420 ADNT--REEFVKPIMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXX 477
A + R+E+VKPIMFSGG+G MP +M +K P +G LL K
Sbjct: 418 AADASQRDEYVKPIMFSGGLGTMPATMREKLPPARGQLLAK--IGGPVYRIGVGGGAASS 475
Query: 478 XXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLE-SDVNPVESIHDQGAGGNGNVLKE 536
+ D LDF AVQRGDAEM N+LNRVVR CL+ + NP+ +IHDQGAGGNGNVLKE
Sbjct: 476 VEIQGSGDAELDFNAVQRGDAEMENKLNRVVRACLDLGEQNPILAIHDQGAGGNGNVLKE 535
Query: 537 LVEP--EGAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPV 594
LVEP GAV+F+KEFQLGDPTIT LELWGAEYQEN+A+LC+ R +LE+ICRRERCP+
Sbjct: 536 LVEPGFAGAVIFSKEFQLGDPTITALELWGAEYQENNAILCNADQRELLEKICRRERCPI 595
Query: 595 SFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKL-PYDLHLEAVLGNMPRKTFDLQ 653
SFVG VTGDG ++L+E + D + L ++S++ P+DL L+ VLG+MP++T+DL+
Sbjct: 596 SFVGVVTGDGRVTLLEKPAPK---DLEQALNASNRSEVSPFDLELKYVLGDMPKRTYDLK 652
Query: 654 TEKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTP 713
E+ LS PK + + AL+RVL LV V SKR+LTNKVDRCV GL+AQQQCVGPL P
Sbjct: 653 REQTPLKELSLPKGLLLDEALERVLSLVAVGSKRFLTNKVDRCVGGLIAQQQCVGPLQAP 712
Query: 714 LADCAIIALSYYDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKC 773
LAD A+ +S++ G ATSIGTQ +KGLLDPAA AR+ + EAL+NLVF ISEL DVKC
Sbjct: 713 LADYALTTVSHFSHSGIATSIGTQPLKGLLDPAAMARMCVAEALSNLVFVKISELADVKC 772
Query: 774 SGNWMWAGKTGVEXXXXXXXXXXXXXXMRALGVAVDGGKDSLSMCAHVAGEKVKSPGTLV 833
SGNWMWA K E + L +A+DGGKDSLSM A V GE +KSPGTLV
Sbjct: 773 SGNWMWAAKLPGEGARMFDACKELCQILEELHIAIDGGKDSLSMAAKVGGETIKSPGTLV 832
Query: 834 VSTYAPCPDITVKIEPALKEENSALVHAPV---SPGKYRLGGSALAQCYKQLGDNXXXXX 890
+STYAPCPD+ +K+ P LK + + + RLGGSALAQ Y Q G +
Sbjct: 833 ISTYAPCPDVRLKVTPDLKGPGAGSKTSLLWINLENSARLGGSALAQAYAQQGKDTPNLT 892
Query: 891 XXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVN-------- 942
F +TQ LL + + +GHD+S+GG + VLEM IGG+ GL + ++
Sbjct: 893 RSDVLGKAFAVTQSLLGDGLIQAGHDVSDGGLLVCVLEMAIGGLSGLRVDLSEPLAKLKN 952
Query: 943 -----VAANVSPIEALFNEELGIVLEVSKNDLPYVLSEYNNNGVGAQHIGYTGKYGMDSQ 997
N + LF EE G V+EV DL V S Y GV ++G T +G+DS+
Sbjct: 953 FDKSVEKLNRPELAVLFAEECGWVVEVLDTDLERVRSTYEKAGVPNYYLGVTEGFGLDSR 1012
Query: 998 VVINLNGVNVLDTVLIDVFRMWEETSYRLECLQANTDCVLQEWKVLEKRKGATYNVTFDP 1057
VV+ +LD L +++ WE TSY LE LQAN +C E+ LE R+ Y +
Sbjct: 1013 VVLKNGKSELLDQPLRVLYKKWERTSYELEKLQANPECAEAEYNSLEYRQAPQYRGPQNV 1072
Query: 1058 TAAVIKTKS---IKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQG 1114
A + +S ++VAVLREEG+N +REM+A L+ ANF+V DVTMSDL ++ ++G
Sbjct: 1073 QAELTLKRSSAPVRVAVLREEGVNSEREMMACLLRANFEVHDVTMSDLLQGTASVSQYRG 1132
Query: 1115 VVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWV 1174
++FPGGFSYADTLGSAKGWAA IL + L QF FK R+D FSLG+CNGCQLM ++G+V
Sbjct: 1133 LIFPGGFSYADTLGSAKGWAANILHNPRLLPQFEAFKRRQDVFSLGICNGCQLMTLIGFV 1192
Query: 1175 DPDSNSKGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGE 1234
+ G++ + L HN S+RFECRW+ VKI N + + M VLG WVAHGE
Sbjct: 1193 GSAKSEVGAD-PDVALLHNKSQRFECRWATVKIPSNRS---IMLGSMKDLVLGCWVAHGE 1248
Query: 1235 GRFTVADGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMM 1294
GRF D L+ L V +QYVDD GKPTE+YP+NPNGSP G+AG+ S DGRH+A+M
Sbjct: 1249 GRFAFRDEKLISHLQSEQLVTLQYVDDVGKPTELYPLNPNGSPQGIAGLCSSDGRHLALM 1308
Query: 1295 PHPERCVLRWQCPAPCPTVTNPSVRNSQASPWLRLFQNAYSWAI 1338
PHPERC +Q P P+ S S+ SPW +F NAY+W +
Sbjct: 1309 PHPERCSSMYQWPY-VPSSFEVSPTQSE-SPWQIMFNNAYNWCV 1350
>UniRef50_O15067 Cluster: Phosphoribosylformylglycinamidine synthase;
n=26; Eukaryota|Rep: Phosphoribosylformylglycinamidine
synthase - Homo sapiens (Human)
Length = 1338
Score = 1242 bits (3077), Expect = 0.0
Identities = 657/1339 (49%), Positives = 856/1339 (63%), Gaps = 50/1339 (3%)
Query: 22 QKLKFVDSDIKDLSTELCYHVE-LAEGCEYLNINQIKVLKWLLSSPLQPQAVRNETIFKS 80
+KL+ +++ + TELCY+V AE + + K L WL PL V E+
Sbjct: 24 RKLQGKLPELQGVETELCYNVNWTAEALP--SAEETKKLMWLFGCPLLLDDVARESWLLP 81
Query: 81 NDNSQLLIEIGPRFNFSTADSSNSVQICESVGLRDVVRLEVSTRYLITFGKQKNVTEKHF 140
N LL+E+GPR NFST S+N V +C + GL V R+E + RY ++F +
Sbjct: 82 GSND-LLLEVGPRLNFSTPTSTNIVSVCRATGLGPVDRVETTRRYRLSFAHPPSA---EV 137
Query: 141 ENLA-AVLHDRMTQCVYTKDNLPRKSFN-EGLPKDLEPWFVVPLQEQGISAMRKVNDKLG 198
E +A A LHDRMT+ + P +SF+ E +P+ L + + +G A+ K N +LG
Sbjct: 138 EAIALATLHDRMTEQHFPH---PIQSFSPESMPEPLNG--PINILGEGRLALEKANQELG 192
Query: 199 LAFDTWDMEFYMDLFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLI 258
LA D+WD++FY F +L+R+P++VE FDLAQSNSEHSRHWFFKG+L +DG+++ SL
Sbjct: 193 LALDSWDLDFYTKRF-QELQRNPSTVEAFDLAQSNSEHSRHWFFKGQLHVDGQKLVHSLF 251
Query: 259 DMVASTQKTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRGPSQVIQKKTESDIIFTAETH 318
+ + STQ++SN NNV+KF DNSSAI+G + LRP + PS+ Q++ ++FTAETH
Sbjct: 252 ESIMSTQESSNPNNVLKFCDNSSAIQGKEVRFLRPEDPTRPSRFQQQQGLRHVVFTAETH 311
Query: 319 NMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEY 378
N PT V PFSGATTGTGGRIRDVQ GRG H VAGTAGY GNLHIPGY+LPWE+ ++Y
Sbjct: 312 NFPTGVCPFSGATTGTGGRIRDVQCTGRGAHVVAGTAGYCFGNLHIPGYNLPWEDLSFQY 371
Query: 379 PSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKPIMFSGGIG 438
P NFA PL++ IEASNGASDYGNKFGEPV++GF +S GL+ D R E++KPIMFSGGIG
Sbjct: 372 PGNFARPLEVAIEASNGASDYGNKFGEPVLAGFARSLGLQLPDGQRREWIKPIMFSGGIG 431
Query: 439 YMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRGDA 498
M I K P+ GM +VK + D LDFGAVQRGD
Sbjct: 432 SMEADHISKEAPEPGMEVVKVGGPVYRIGVGGGAASSVQVQGDNTSD--LDFGAVQRGDP 489
Query: 499 EMGNRLNRVVRGCLESDV-NPVESIHDQGAGGNGNVLKELVEPEGAVVFTKEFQLGDPTI 557
EM ++NRV+R C+E+ NP+ S+HDQGAGGNGNVLKEL +P GA+++T FQLGDPT+
Sbjct: 490 EMEQKMNRVIRACVEAPKGNPICSLHDQGAGGNGNVLKELSDPAGAIIYTSRFQLGDPTL 549
Query: 558 TTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGEVTGDGYMSLIEDSYTEKF 617
LE+WGAEYQE++ALL NR L + RERCP FVG +TGD + L++D
Sbjct: 550 NALEIWGAEYQESNALLLRSPNRDFLTHVSARERCPACFVGTITGDRRIVLVDDREC-PV 608
Query: 618 LDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKRTKLPLSFPKDITVKSALDRV 677
+ + P DL LE VLG MPRK F LQ + PL+ P ++V AL+RV
Sbjct: 609 RRNGQGDAPPTPPPTPVDLELEWVLGKMPRKEFFLQRKPPMLQPLALPPGLSVHQALERV 668
Query: 678 LRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALSYYDLVGSATSIGTQ 737
LRL VASKRYLTNKVDR V GLVAQQQCVGPL TPLAD A++ALS+ +L+G+AT++G Q
Sbjct: 669 LRLPAVASKRYLTNKVDRSVGGLVAQQQCVGPLQTPLADVAVVALSHEELIGAATALGEQ 728
Query: 738 NIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEXXXXXXXXXXX 797
+K LLDP ARL++ EALTNLVFA +++L DVKCSGNWMWA K E
Sbjct: 729 PVKSLLDPKVAARLAVAEALTNLVFALVTDLRDVKCSGNWMWAAKLPGEGAALADACEAM 788
Query: 798 XXXMRALGVAVDGGKDSLSMCAHVAGEKVKSPGTLVVSTYAPCPDITVKIEPALK--EEN 855
M ALGVAVDGGKDSLSM A V E V++PG+LV+S YA CPDIT + P LK E
Sbjct: 789 VAVMAALGVAVDGGKDSLSMAARVGTETVRAPGSLVISAYAVCPDITATVTPDLKHPEGR 848
Query: 856 SALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGH 915
L++ +SPG++RLGG+ALAQC+ QLG++ F ITQ LLK++ L SGH
Sbjct: 849 GHLLYVALSPGQHRLGGTALAQCFSQLGEHPPDLDLPENLVRAFSITQGLLKDRLLCSGH 908
Query: 916 DISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGIVLEVSKNDLPYVLSE 975
D+S+GG +T +LEM G GL + V V V + LF EE G+VLEV + DL VL
Sbjct: 909 DVSDGGLVTCLLEMAFAGNCGLQVDVPV-PRVDVLSVLFAEEPGLVLEVQEPDLAQVLKR 967
Query: 976 YNNNGVGAQHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFRMWEETSYRLECLQANTDC 1035
Y + G+ +G+TG+ G + V +++NG VL+ + ++ +WEETS++L+ LQA C
Sbjct: 968 YRDAGLHCLELGHTGEAGPHAMVRVSVNGAVVLEEPVGELRALWEETSFQLDRLQAEPRC 1027
Query: 1036 VLQEWKVLEKRKGATYNV--TFDPTAAVIKT---KSIKVAVLREEGINGDREMIASLMLA 1090
V +E + L +R G +Y + TF P A+V + S +VA+LREEG NGDREM + LA
Sbjct: 1028 VAEEERGLRERMGPSYCLPPTF-PKASVPREPGGPSPRVAILREEGSNGDREMADAFHLA 1086
Query: 1091 NFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHF 1150
F+V+DVTM DL + I LD F+GV F GGFSYAD LGSAKGWAA + F ++ F
Sbjct: 1087 GFEVWDVTMQDLCSGAIGLDTFRGVAFVGGFSYADVLGSAKGWAAAVTFHPRAGAELRRF 1146
Query: 1151 KDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSN--------KAQIFLDHNSSERFECRW 1202
+ R DTFSLGVCNGCQL+A+LGWV D N + + + L HN S R+E RW
Sbjct: 1147 RKRPDTFSLGVCNGCQLLALLGWVGGDPNEDAAEMGPDSQPARPGLLLRHNLSGRYESRW 1206
Query: 1203 SAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLYKNGQVAVQYVDDD 1262
++V++ + RGM G+VL VW AHGEG + L ++ G + + DDD
Sbjct: 1207 ASVRVGPG---PALMLRGMEGAVLPVWSAHGEGYVAFSSPELQAQIEARGLAPLHWADDD 1263
Query: 1263 GKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQC---PAPCPTVTNPSVR 1319
G PTE YP+NPNGSP G+AG+ S DGRH+A+MPHPER V WQ P P T+T
Sbjct: 1264 GNPTEQYPLNPNGSPGGVAGICSCDGRHLAVMPHPERAVRPWQWAWRPPPFDTLT----- 1318
Query: 1320 NSQASPWLRLFQNAYSWAI 1338
SPWL+L NA +W +
Sbjct: 1319 ---TSPWLQLSINARNWTL 1334
>UniRef50_Q9M8D3 Cluster: Probable phosphoribosylformylglycinamidine
synthase, chloroplast precursor; n=40; Eukaryota|Rep:
Probable phosphoribosylformylglycinamidine synthase,
chloroplast precursor - Arabidopsis thaliana (Mouse-ear
cress)
Length = 1387
Score = 1176 bits (2912), Expect = 0.0
Identities = 624/1348 (46%), Positives = 849/1348 (62%), Gaps = 45/1348 (3%)
Query: 3 IVRFFSTEAFSLHKTNEILQKLKF-VDSDIKDLSTELCYHVELAEGCEYLNINQIKVLKW 61
++ F+ E+L+ ++ + + I L+TE +++ L L ++ VLKW
Sbjct: 67 VIHFYRVPLIQESANAELLKAVQTKISNQIVSLTTEQSFNIGLESK---LKDEKLSVLKW 123
Query: 62 LLSSPLQPQAVRNETIFKSNDNSQL---LIEIGPRFNFSTADSSNSVQICESVGLRDVVR 118
+L +P+ + ++ + L ++E+GPR +F+TA S+N+V IC + GL +V R
Sbjct: 124 ILQETYEPENLGTDSFLERKKQEGLHAVIVEVGPRLSFTTAWSTNAVSICRACGLDEVTR 183
Query: 119 LEVSTRYLITFGKQKNVTEKHFENLAAVLHDRMTQCVYTKDNLPRKSFNEGL-PKDLEPW 177
LE S RYL+ F K+ + E + AA++HDRMT+CVYT+ + SF + P++++
Sbjct: 184 LERSRRYLL-FSKEP-LLENQIKEFAAMVHDRMTECVYTQKLV---SFETNVVPEEVK-- 236
Query: 178 FVVPLQEQGISAMRKVNDKLGLAFDTWDMEFYMDLFVNKLKRDPTSVELFDLAQSNSEHS 237
VP+ E+G A+ ++N ++GLAFD D+++Y LF +KRDPT+VELFD+AQSNSEHS
Sbjct: 237 -YVPVMEKGRKALEEINQEMGLAFDEQDLQYYTRLFREDIKRDPTNVELFDIAQSNSEHS 295
Query: 238 RHWFFKGKLVLDGKEINESLIDMVASTQKTSNNNNVIKFGDNSSAIKGFQHTILRPTNVR 297
RHWFF G +V+DGK +++SL+ +V ST + + NN+VI F DNSSAI+GF LRP
Sbjct: 296 RHWFFAGNMVIDGKPMDKSLMQIVKSTWEANRNNSVIGFKDNSSAIRGFLVNQLRPLLPG 355
Query: 298 GPSQVIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGY 357
+ + DI+FTAETHN P AVAP+ GA TG GGRIRD GRG VA T+GY
Sbjct: 356 SVCLLDVSARDLDILFTAETHNFPCAVAPYPGAETGAGGRIRDTHATGRGSFVVASTSGY 415
Query: 358 SVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGL 417
VGNL++ G PWE+ ++YPSN A+PLQI+I+ASNGASDYGNKFGEP+I G+ +++G+
Sbjct: 416 CVGNLNMEGSYAPWEDSSFQYPSNLASPLQILIDASNGASDYGNKFGEPMIQGYTRTFGM 475
Query: 418 KNADNTREEFVKPIMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXX 477
+ R E++KPIMFS GIG + H+ I K +P+ GML+VK
Sbjct: 476 RLPSGDRREWLKPIMFSAGIGQIDHTHITKGEPEVGMLVVKIGGPAYRIGMGGGAASSMV 535
Query: 478 XXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLE-SDVNPVESIHDQGAGGNGNVLKE 536
DA LDF AVQRGDAEM +L RVVR C+E + NP+ SIHDQGAGGN NV+KE
Sbjct: 536 SGQNDAE---LDFNAVQRGDAEMSQKLYRVVRACIEMGEKNPIISIHDQGAGGNCNVVKE 592
Query: 537 LVEPEGAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSF 596
++ P+GA + + +GD T++ LE+WGAEYQE DA+L +R IL+ IC+RER ++
Sbjct: 593 IIYPQGAEIDIRAVVVGDHTMSVLEIWGAEYQEQDAILVKAESREILQSICKRERLSMAV 652
Query: 597 VGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEK 656
+G + G G +LI+ + K E L + DL LE VLG+MP+KTF
Sbjct: 653 IGTINGGGRCTLIDSTAAAKC--SKEGLPPPPPA---VDLELEKVLGDMPKKTFKFNRIA 707
Query: 657 RTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLAD 716
+ PL IT+ AL RVLRL +V+SKR+LT KVDRCVTGLVAQQQ VGPL LAD
Sbjct: 708 YAREPLDIAPGITLMDALKRVLRLPSVSSKRFLTTKVDRCVTGLVAQQQTVGPLQITLAD 767
Query: 717 CAIIALSYYDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGN 776
A+IA ++ DL G A +IG Q IKGLLDP A ARL++GEALTNLV+A ++ L DVK SGN
Sbjct: 768 VAVIAQTFTDLTGGACAIGEQPIKGLLDPKAMARLAVGEALTNLVWAKVTALSDVKASGN 827
Query: 777 WMWAGKTGVEXXXXXXXXXXXXXXMRALGVAVDGGKDSLSMCAHVAGEKVKSPGTLVVST 836
WM+A K E M LG+A+DGGKDSLSM AH GE VK+PG LV+S
Sbjct: 828 WMYAAKLEGEGSAMYDAAIALSEAMIELGIAIDGGKDSLSMAAHADGEVVKAPGNLVISA 887
Query: 837 YAPCPDITVKIEPALK--EENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXX 894
Y CPDIT + P LK ++ L+H ++ GK RLGGSALAQ + Q+G++
Sbjct: 888 YVTCPDITKTVTPDLKLGGDDGILLHVDLAKGKRRLGGSALAQVFGQIGNDCPDLDDVPY 947
Query: 895 XKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAAN-VSPIEAL 953
K++F Q L+ E + +GHDIS+GG + T LEM G +G+NL ++A+N +S E L
Sbjct: 948 LKNVFDGVQALIAENLVSAGHDISDGGLVVTALEMAFAGNKGINL--DLASNGISLFETL 1005
Query: 954 FNEELGIVLEVSKNDLPYVLSEYNNNGVGAQHIGYTGKYGMDSQVV-INLNGVNVLDTVL 1012
F+EELG+VLE+SK +L V+ + V A+ IG DS ++ + ++G+ L
Sbjct: 1006 FSEELGLVLEISKTNLDAVMEKLRAFDVTAEIIGNV----TDSPLIEVKVDGITHLSEKT 1061
Query: 1013 IDVFRMWEETSYRLECLQANTDCVLQEWKVLEKRKGATYNVTFDPTAA----VIKTKSIK 1068
+ MWE+TS++LE LQ CV E + L+ R + ++F P++ + + K
Sbjct: 1062 SFLRDMWEDTSFQLEKLQRLASCVEMEKEGLKFRHEPNWKLSFIPSSTNNNYMSQGMIPK 1121
Query: 1069 VAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLG 1128
VAV+REEG NGDREM A+ A F+ +DVT+SDL ITLD F+G+VF GGFSYAD L
Sbjct: 1122 VAVIREEGSNGDREMSAAFYAAGFEPWDVTVSDLLAGDITLDQFRGIVFVGGFSYADVLD 1181
Query: 1129 SAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQI 1188
SAKGWAA I F+E + SQF F R DTFSLG+CNGCQLMA+LGWV + +Q
Sbjct: 1182 SAKGWAASIRFNEPVLSQFQEFYKRPDTFSLGICNGCQLMALLGWVPGPQVGGSLDTSQP 1241
Query: 1189 FLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKL 1248
HN S RFECR+++V I ++ + + +GM GS LGVW AHGEGR D +LD +
Sbjct: 1242 RFVHNESGRFECRFTSVTIKDSPS---IMLKGMEGSTLGVWAAHGEGRAYFPDEGVLDHM 1298
Query: 1249 YKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCPA 1308
+ ++Y DDDG TE YP N NGSP G+A + S DGRH+AMMPHPERC L WQ P
Sbjct: 1299 LHSDLAPLRYCDDDGNVTEAYPFNLNGSPLGIAAICSPDGRHLAMMPHPERCFLMWQFPW 1358
Query: 1309 PCPTVTNPSVRNSQASPWLRLFQNAYSW 1336
T+ V + SPWL++FQNA W
Sbjct: 1359 ---YPTSWDVEKAGPSPWLKMFQNARDW 1383
>UniRef50_Q54JC8 Cluster: Phosphoribosylformylglycinamide synthase;
n=1; Dictyostelium discoideum AX4|Rep:
Phosphoribosylformylglycinamide synthase - Dictyostelium
discoideum AX4
Length = 1355
Score = 1163 bits (2880), Expect = 0.0
Identities = 630/1386 (45%), Positives = 856/1386 (61%), Gaps = 86/1386 (6%)
Query: 1 MSIVRFFSTEAFSLHKTNEILQKLKFVDS-DIKDLSTELCYHVELAEGCEYLNINQIKVL 59
M+I +F+ A S ++ + LK + DI+ + TE C++V+ + + LN ++ L
Sbjct: 1 MTIQQFYRKPAISEYEIKLLKNNLKKQHNIDIESIETEYCFNVQYPDNHK-LNESEQSTL 59
Query: 60 KWLLSSPLQPQAVRNETIF----KSNDNSQLLIEIGPRFNFSTADSSNSVQICESVGLRD 115
WLLS +P+ + F + ++++IE+GPR NF+T SSN+ IC+S L
Sbjct: 60 VWLLSETFEPKNFSIDKSFLKTTTTTTENEIIIEVGPRMNFTTTYSSNATSICKSCNLSI 119
Query: 116 VVRLEVSTRYLITFGKQKNVTEKHFENLAAVLHDRMTQCVYTKDNLPRKSFNEGL-PKDL 174
+ R+E S RYL+ ++EK + ++HDRMT+C+Y P KSF+ G+ PK +
Sbjct: 120 IDRIERSRRYLVK--SVSKLSEKQIDQFLELIHDRMTECLYPT---PIKSFDTGIIPKAV 174
Query: 175 EPWFVVPLQEQGISAMRKVNDKLGLAFDTWDMEFYMDLFVNKLKRDPTSVELFDLAQSNS 234
+P+ E+G +A+ +VN ++GLAFD D+ Y DLF N+LKR+P+ VE FD+ QSNS
Sbjct: 175 ---VYIPVVEEGRAALERVNKEMGLAFDEQDLALYTDLFQNQLKRNPSDVECFDIGQSNS 231
Query: 235 EHSRHWFFKGKLVLDGKEINESLIDMVASTQKTSNNNNVIKFGDNSSAIKGFQHTILRPT 294
EHSRHWFF GKL++DG +++L +V +T K + N++I F DNSS+IKGF+ +L P
Sbjct: 232 EHSRHWFFNGKLIVDGNMSDKTLFQIVKNTLKANPQNSLIAFSDNSSSIKGFKTKVLIPK 291
Query: 295 NVRGPSQVIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGT 354
+ S+ ++ + E IIFTAETHN PT +APF GA TGTGGR+RD GRG VAGT
Sbjct: 292 SQIEASEYLEGEREQPIIFTAETHNFPTGIAPFEGAETGTGGRLRDTHATGRGSLVVAGT 351
Query: 355 AGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQS 414
GY VGNL+IPGY+LPWE K + YP N A PL+I IEASNGASDYGNKFGEPVI GF +S
Sbjct: 352 VGYCVGNLNIPGYELPWENKEYNYPDNMANPLKIEIEASNGASDYGNKFGEPVIIGFTRS 411
Query: 415 YGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXX 474
YG + R E++KPIMFSGGIG+M +KK +P+ GM++VK
Sbjct: 412 YGNTLPNGERREWIKPIMFSGGIGFMDERHLKKEQPEIGMVVVKAGGPAYRIGMGGGSAS 471
Query: 475 XXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLESDV----NPVESIHDQGAGGN 530
H LDF AVQRGDAEMG +LNR+VR C+ES++ NP+ S+HDQGAGG
Sbjct: 472 SMVGGD---NKHELDFSAVQRGDAEMGQKLNRIVRSCVESEIHGGCNPIVSVHDQGAGGA 528
Query: 531 GNVLKELVEPEGAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRE 590
GNVLKE+V+P GA ++ GDPT++ +E+WGAEYQENDALL ++ L+++ RE
Sbjct: 529 GNVLKEIVDPLGAKIYLDRIISGDPTLSAMEIWGAEYQENDALLIKAEHKDYLKKVSERE 588
Query: 591 RCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTF 650
R P++FVG+VTGDG LI + P +L L+ VL MP KTF
Sbjct: 589 RLPIAFVGDVTGDGIAQLI-----------------TKDGETPVNLPLDKVLQKMPPKTF 631
Query: 651 DLQTEKRTKLPLSFPKDITV-------KSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQ 703
L ++ P + PK++ V L+RVLRL++V SKR+L NKVDR VTGLVA+
Sbjct: 632 VLDHVEKQLKPFTLPKELLVGDHQTCFNECLNRVLRLLSVGSKRFLINKVDRAVTGLVAR 691
Query: 704 QQCVGPLHTPLADCAIIALSYYDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFA 763
QQCVGPLHTP+++ A+I+ Y+ G+ATSIG Q IKG + + A L++GEALTNL++A
Sbjct: 692 QQCVGPLHTPVSNVAVISSGYFGKSGAATSIGEQPIKGFISAKSMAYLTVGEALTNLMWA 751
Query: 764 GISELEDVKCSGNWMWAGKTGVEXXXXXXXXXXXXXXMRALGVAVDGGKDSLSMCAHV-- 821
I++L DVKCSGNWMWA K E M LG+A+DGGKDSLSM A
Sbjct: 752 SITDLGDVKCSGNWMWAAKLKGEGVELYDAAIEMHDVMVELGIAIDGGKDSLSMAAKAPK 811
Query: 822 ---AGEKVKSPGTLVVSTYAPCPDITVKIEPALK---EENSALVHAPVSPGKYRLGGSAL 875
+ E VK+PG LVVSTY PC DIT+ + P LK +++S +++ + +GGSAL
Sbjct: 812 SDGSQELVKAPGALVVSTYVPCDDITLTVTPDLKLSSKDDSVILYLDLGCANNFIGGSAL 871
Query: 876 AQCYKQLGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVR 935
Q + Q+G N K+ F QKL+K++ + +GHD S+GG ITT++EM + G R
Sbjct: 872 TQVFNQVG-NDEPHHNTPLLKNTFMAIQKLVKQQLISAGHDRSDGGLITTLIEMSLSGNR 930
Query: 936 GLNL-----HVNVAANVSPIEALFNEELGIVLEVSKNDLPYVLSEYNNNGVGAQHIGYT- 989
GL + H + + +S I+ LF+EELG VLE+ K++ VL V Q IG T
Sbjct: 931 GLEINLPDTHNSDQSPLSIIKLLFSEELGAVLEIKKSNQQIVLDILKQFNVPTQVIGNTS 990
Query: 990 -------GKYGMDSQV-VINLNGVNVLDTVLIDVFRMWEETSYRLECLQANTDCVLQEWK 1041
G D + ++ + + + L + + WEETSY+LE LQAN V E K
Sbjct: 991 CNNNNNNNNNGSDEDLFIVKVGDKLIYNIKLSQLSKQWEETSYQLELLQANPTFVESEMK 1050
Query: 1042 VLEKR-----KGATYNVTF--DPTA---AVIKTKSIKVAVLREEGINGDREMIASLMLAN 1091
L KR KG YN+T+ P + A++ K+ KVAV+REEG NGDREM A+ A
Sbjct: 1051 NLLKRATGKGKGPNYNMTYKISPISKELALLANKAPKVAVIREEGSNGDREMAAAFHFAG 1110
Query: 1092 FDVFDVTMSDLQNKKITLD-AFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHF 1150
F FDVTMSDL N I LD F+GV F GGFSY D + SAKGWA I F++ +S QF HF
Sbjct: 1111 FQAFDVTMSDLLNGNIQLDERFKGVAFVGGFSYGDVMDSAKGWAGSIRFNQQVSKQFDHF 1170
Query: 1151 KDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQIFLDHNSSERFECRWSAVKIHEN 1210
R DTFSLG+CNGCQLMA+LGWV P + +++ + HN+S RFE RW VKI +
Sbjct: 1171 YGRNDTFSLGLCNGCQLMALLGWV-PYRGIEQTHQPRFI--HNASGRFESRWVNVKIMPS 1227
Query: 1211 ENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLYKNGQVAVQYVDDDGKPTEVYP 1270
+ +GM GSVLGVW HGEGRF D S+++ + N ++YVDDDG+ TE YP
Sbjct: 1228 ---PALLLKGMEGSVLGVWSQHGEGRFWSEDQSIVNDIKANNLSPIRYVDDDGEITESYP 1284
Query: 1271 MNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCPAPCPTVTNPSVRNSQASPWLRLF 1330
NP+G+ +G A + S+DGRH+A+MPHPER L WQ P + Q SPW+++F
Sbjct: 1285 FNPSGTQEGFASLCSKDGRHLAIMPHPERSFLSWQWPFMPENIKQNVGGLDQPSPWIKIF 1344
Query: 1331 QNAYSW 1336
QNA S+
Sbjct: 1345 QNAKSF 1350
>UniRef50_Q19311 Cluster: Probable phosphoribosylformylglycinamidine
synthase; n=2; Caenorhabditis|Rep: Probable
phosphoribosylformylglycinamidine synthase -
Caenorhabditis elegans
Length = 1343
Score = 1035 bits (2563), Expect = 0.0
Identities = 594/1358 (43%), Positives = 805/1358 (59%), Gaps = 100/1358 (7%)
Query: 33 DLSTELCYHVELAEGCEYLNINQIKVLKWLLSSPLQPQAVRNETIFKSNDNSQLLIEIGP 92
D+S E CYHV + + E ++ N K++ L SP + + + + + IEIGP
Sbjct: 34 DVSVEYCYHV-ITQEPELISSNWEKLVTLLSHSPFETSVWKESQLHPEHGKN---IEIGP 89
Query: 93 RFNFSTADSSNSVQICESVGLRDVVRLEVSTRYLITFGKQKNVTEKHFENLAAVLHDRMT 152
R TA +N + I ES G+++V R+E RYL+ + +V F +AA D+MT
Sbjct: 90 RTAVKTAACTNILSIFESSGIKNVERIERGIRYLV----EDDVDVNEFFEIAA---DKMT 142
Query: 153 QCVYTKDNLPRKSFNEGLPKDLEPWFVVPLQEQGISAMRKVNDKLGLAFDTWDMEFYMDL 212
+ +Y D F++ +E F++ + E + + K N++LGLA D D++FY D
Sbjct: 143 EAIYGND----VKFDDE-SHQIEKVFLIDVLESKQNLI-KANEELGLALDQLDLDFYYDF 196
Query: 213 FVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLIDMVASTQKTSNNNN 272
FVNK+K++PT VELFDLAQS+SEHSRHWFF+G++ +D ++ + SL+ + T +SN+N+
Sbjct: 197 FVNKVKKNPTDVELFDLAQSDSEHSRHWFFRGEIWIDDRKRDGSLMKTIRETLDSSNDNS 256
Query: 273 VIKFGDNSSAIKGFQHTI-LRPTNVRGPSQVIQKKTESDIIFTAETHNMPTAVAPFSGAT 331
+I F DNSSAI+GF+ LRP + S +I S +I++AETHN PTAV PF GAT
Sbjct: 257 LIAFCDNSSAIRGFESVCRLRPNDPTTVSPMIAIFPPSHLIYSAETHNFPTAVCPFQGAT 316
Query: 332 TGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIE 391
TGTGGRIRD+ GRG + +AGT GYS GNL++PG LPWE++ +EYP++ + P +I IE
Sbjct: 317 TGTGGRIRDIHATGRGAYEIAGTVGYSFGNLNLPGLPLPWEDETFEYPTSISEPAKIAIE 376
Query: 392 ASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKNKPD 451
ASNGASDYGNKFGEPVISGF +S+G + + R E++KPIMFSGGIG + ++K
Sbjct: 377 ASNGASDYGNKFGEPVISGFARSFGQRLENGERCEYLKPIMFSGGIGAIDKDEVRKEPCA 436
Query: 452 KGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGC 511
+VK R++ LDF AVQRGDAEMG +L+RVVR C
Sbjct: 437 PHQKVVKIGGPVYRIGVGGGAASSVSVQGN--RENQLDFAAVQRGDAEMGGKLHRVVRAC 494
Query: 512 LES-DVNPVESIHDQGAGGNGNVLKELVEPEGAVVFTKEFQLGDPTITTLELWGAEYQEN 570
E NP+ +IHDQGAGGNGNV+KELVE G V + FQLGD +I+ ELW AEYQEN
Sbjct: 495 AERIGGNPLMAIHDQGAGGNGNVIKELVEGCGVTVKSDTFQLGDESISLRELWTAEYQEN 554
Query: 571 DALLCSKANRHILEEICRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKS 630
DA L + L+ I +RE+C VS VGEV ++ +R+KL KS
Sbjct: 555 DAALVDASLLDALQTISKREKCHVSVVGEV------------------EKEQRVKLLGKS 596
Query: 631 -KLPYDLHLEAVLGNMPRKTFDLQTEKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYL 689
++ DL LG +K F L++ R L P+++TV+ AL RVL L +VASKRYL
Sbjct: 597 GEIAVDLDTRQ-LGEREKKVFKLKSAPRVLKKLELPENLTVRKALKRVLMLPSVASKRYL 655
Query: 690 TNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALSYYDLVGSATSIGTQNIKGLLDPAAGA 749
T KVDR VTGLVAQQQCVGPLHTPLAD A++ALS++D VG A S+G Q IK L+D GA
Sbjct: 656 TCKVDRSVTGLVAQQQCVGPLHTPLADVAVVALSHFDTVGGAVSLGEQPIKMLIDAEKGA 715
Query: 750 RLSLGEALTNLVFAGISE-------------------LEDVKCSGNWMWAGKTGVEXXXX 790
R+ + E + NL++A I++ L+DVK SGNWMWA K E
Sbjct: 716 RMCIAETIMNLIWAPITDLKVHFLIYFYSKFQKLLLSLKDVKMSGNWMWAAKCDGEGARL 775
Query: 791 XXXXXXXXXXMRALGVAVDGGKDSLSMCAHVAGEKVKSPGTLVVSTYAPCPDITVKIEPA 850
+R +G A+DGGKDSLSM GE VKSPGTLV+S YAPC ++T + P+
Sbjct: 776 VDAVGALCRGLREIGCAIDGGKDSLSMAVTAHGEVVKSPGTLVLSAYAPCTNVTKVVNPS 835
Query: 851 LKE-ENSALVHAPV--SPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLK 907
LK S ++ + S K RLGGSALAQ Y Q+GD+ +F I Q+LL
Sbjct: 836 LKAVPGSKILWIKIGSSEEKMRLGGSALAQVYSQIGDDCPDIENFSEISKVFSIVQQLLN 895
Query: 908 EKKL---------ISGHDISEGGFITTVLEMGIGGVRGLNLHVNVA-ANVSPIEALFNEE 957
++L ++GHDIS+GG +T +LEM G +++ + N+ PI+ LF EE
Sbjct: 896 REELAGPLRKPIILAGHDISDGGLLTAILEMAFAGNVSIDIDIKPPNQNIKPIDILFAEE 955
Query: 958 LGIVLEVSKNDLPYVLSEYNNNGVGAQHIG-YTGKYGMDSQVVINLNGVNVLDTVLIDVF 1016
GI+LEVS + VL ++ G+ Q IG + +G D+ V I++NG ++ L+D+
Sbjct: 956 CGILLEVSNPE--NVLHIFSEAGIKCQEIGKASAVFGPDAHVKIHVNGHLEINEKLVDLR 1013
Query: 1017 RMWEETSYRLECLQANTDCVLQEWKVLEKRKGATYNVTFD--PTAAVIKTKSI-----KV 1069
WE RL Q N + + +V + Y FD A I + +V
Sbjct: 1014 EEWELVGDRLGEFQTNPKSLKEAREVRRTCQKINYKCDFDWYYNPAFIHNEQYFSTAPRV 1073
Query: 1070 AVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGS 1129
A++REEG NGDREM ++ LA F FDVTM+D+ TL+A++GV F GGFSYAD LGS
Sbjct: 1074 AIIREEGSNGDREMASAFTLAGFQTFDVTMTDILAGH-TLEAYRGVAFVGGFSYADVLGS 1132
Query: 1130 AKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQIF 1189
AKGWAAG+ F+ES+S QF F+ R DTFS GVCNGCQLMA LGW+ D KG +F
Sbjct: 1133 AKGWAAGVQFNESVSKQFEAFRSRPDTFSYGVCNGCQLMAQLGWIG-DEEQKGPT---VF 1188
Query: 1190 LDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLY 1249
LD N RF+ + VKI +N + + GM SVLG+W +HGEGRFT + L
Sbjct: 1189 LDENECGRFDSSFGPVKIEKNVS---IMLSGMENSVLGLWSSHGEGRFTYRNLQNFQNLK 1245
Query: 1250 KNGQVAVQYVD-------DDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVL 1302
NGQV +++ D D G YP NPNGS D +A + SRDGRH+AMMPH +R L
Sbjct: 1246 TNGQVCIRFCDDRGMTGADHGSVKLPYPWNPNGSIDDVAAICSRDGRHLAMMPHADRSFL 1305
Query: 1303 RWQC--PAPCPTVTNPSVRNSQASPWLRLFQNAYSWAI 1338
WQ + P + SPW+++F+NAY+W +
Sbjct: 1306 TWQWAESSEVPWNARFDQKTVALSPWIKMFRNAYNWCL 1343
>UniRef50_Q6AQE0 Cluster: Probable phosphoribosylformylglycinamidine
synthase; n=1; Desulfotalea psychrophila|Rep: Probable
phosphoribosylformylglycinamidine synthase - Desulfotalea
psychrophila
Length = 1267
Score = 986 bits (2440), Expect = 0.0
Identities = 548/1313 (41%), Positives = 760/1313 (57%), Gaps = 63/1313 (4%)
Query: 33 DLSTELCYHVELAEGCEYLNINQIKVLKWLLSSPLQPQAVRNETIFKSNDNSQLLIEIGP 92
D S C++VE + L ++ L+ +L+ + V E + + ++E+GP
Sbjct: 13 DESRAYCFNVESSSS---LTPEELNCLRLILAEGFLLETVSFEPVLVGDR----VVELGP 65
Query: 93 RFNFSTADSSNSVQICESVGLRDVVRLEVSTRYLITFGKQKNVTEKHFENLAAVLHDRMT 152
R NF+TA SSN V IC++ GL + R+E S RYL+ +V + F A HDRMT
Sbjct: 66 RMNFATAWSSNMVSICQATGLGIISRVERSRRYLVP----ADVDTQEF---IAAHHDRMT 118
Query: 153 QCVYTKDNLPRKSFNEGLPKDLEPWFVVPLQEQGISAMRKVNDKLGLAFDTWDMEFYMDL 212
+C Y + P +F G+ K E + V L G A+ + G++ D WD Y D
Sbjct: 119 ECHYPQ---PITTFETGI-KPAEV-YDVDLMSGGADALLNIP---GISMDEWDRNLYYDY 170
Query: 213 FVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLIDMVASTQKTSNNNN 272
FVN+ R+P+ VE+ DL +NSEHSRH FFK K V+DG+E +L D+V T +
Sbjct: 171 FVNQEGRNPSIVEIMDLNNANSEHSRHGFFKAKQVIDGEEQEGTLFDLVTDTLDAHPAGS 230
Query: 273 VIKFGDNSSAIKGFQHTILRPTNVRGPSQVIQKKTESDIIFTAETHNMPTAVAPFSGATT 332
+I F DNSS I G + L P + +++ + + TAETHN PT VAPF GA T
Sbjct: 231 IIAFKDNSSVIAGHSFSALVPESPGQSCPFVRRDVTYNPLLTAETHNFPTGVAPFPGAET 290
Query: 333 GTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEA 392
GTGGR+RD G+G +AGTAGY VGNL+IPGY+L WE K + P+N A+ L+I IEA
Sbjct: 291 GTGGRLRDTMATGQGSMFIAGTAGYCVGNLNIPGYELSWE-KNYPCPTNLASALEIEIEA 349
Query: 393 SNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKNKPDK 452
SNGASDYGNKFGEP+I GF +S+ ++ + R F+KPIMF+ GIG M K+ +K
Sbjct: 350 SNGASDYGNKFGEPLIQGFTRSFDMRLENGERWGFLKPIMFTAGIGQMNDQHTVKSAEEK 409
Query: 453 GMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCL 512
GM++V+ ++ LDF AVQRGDAEM +++RV+R C
Sbjct: 410 GMIIVQVGGPAYRVGFGGGAASSMLQGENESE---LDFDAVQRGDAEMEQKMSRVIRACN 466
Query: 513 E-SDVNPVESIHDQGAGGNGNVLKELVEPEGAVVFTKEFQLGDPTITTLELWGAEYQEND 571
E + + +E IHDQG GG NV+KELVE G V ++ Q+GDPT++ LE++ AEYQE
Sbjct: 467 EMGEKSLIEIIHDQGCGGPANVIKELVEKSGGRVDIRKIQVGDPTMSVLEIYVAEYQERC 526
Query: 572 ALLCSKANRHILEEICRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSK 631
L N E IC+RE+ +GEVTGD L +
Sbjct: 527 GFLIRPENIEQFENICKREKVGCEILGEVTGDLRFVLFDSE----------------NGT 570
Query: 632 LPYDLHLEAVLGNMPRKTFDLQTEKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTN 691
P D+ L +LG++P+KTF+ K T PL D T++S+L VLRLV+V SKR+LTN
Sbjct: 571 TPVDIDLPVLLGDIPQKTFEDNRTKNTFSPLKLAADATIESSLHDVLRLVSVGSKRFLTN 630
Query: 692 KVDRCVTGLVAQQQCVGPLHTPLADCAIIALSYYDLVGSATSIGTQNIKGLLDPAAGARL 751
KVDR V+GL+AQQQCVGPL PL++ A++A S++ G A++IG Q+IK L+DPAAGAR+
Sbjct: 631 KVDRAVSGLIAQQQCVGPLQLPLSNVAVVAQSHFSKSGIASAIGEQSIKMLIDPAAGARM 690
Query: 752 SLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEXXXXXXXXXXXXXXMRALGVAVDGG 811
++GE LTN+V+A I ++E +KCS NWMWA K E M +G+AVDGG
Sbjct: 691 AVGEVLTNMVWAKIDDMEQIKCSANWMWAPKLAGEGAALYDAAKAMRDTMIEVGMAVDGG 750
Query: 812 KDSLSMCAHVAGEKVKSPGTLVVSTYAPCPDITVKIEPALKEENSALVHAPVSPGKYRLG 871
KDSLSM V E VKSP LV+STYA D+ K+ P LK +S L S G R+G
Sbjct: 751 KDSLSMATMVGDEVVKSPRELVISTYAAMADLDKKVTPDLKHVDSELFFIDPSCGAARMG 810
Query: 872 GSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGI 931
G+ALAQ QLGD K F Q+++ + +GHD S+GG +TT+LEM
Sbjct: 811 GTALAQVNGQLGDKSPDVEDGALLKKAFLAVQEMIDAGLISAGHDRSDGGLVTTMLEMAF 870
Query: 932 GGVRGLNLHVNVAANVSPIEALFNEELGIVLEVSKNDLPYVLSEYNNNGVGAQHIGYTGK 991
G GL + ++ +VS + LFNEELG+++E V G+ +G+T
Sbjct: 871 AGNCGLK--IELSGDVSAHDYLFNEELGMMIECVPGAEAEVEEILVAAGITPVALGFT-- 926
Query: 992 YGMDSQVVINLNGVNVLDTVLIDVFRMWEETSYRLECLQANTDCVLQEWKVLEKRKGATY 1051
D + I+ NG VL+ + + WEETSY+LE LQ N C E +V+ RKG Y
Sbjct: 927 -TADKNISISYNGEQVLNREMQVLRSWWEETSYQLERLQVNVACAESEKEVIYDRKGPAY 985
Query: 1052 NVTFDP---TAAVI-KTKSIKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKI 1107
++ F P TA V+ T K+A+LR+EG N DREM A+ A F+ +DV M+DL +
Sbjct: 986 HLPFAPEPATAEVLAATDKPKIAILRDEGSNSDREMTAAFYSAGFEAWDVCMNDLLAGSV 1045
Query: 1108 TLDAFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQL 1167
L F+G+ GGFSYAD SAKGWAA I F+ L F F +R DTF+ G+CNGCQL
Sbjct: 1046 DLADFRGLAAVGGFSYADVPESAKGWAATIQFNPRLKEMFDTFYNRPDTFTFGICNGCQL 1105
Query: 1168 MAMLGWVDPDSNSKGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLG 1227
++LGWV P + ++ + N S RFE RW+ VK+ + + + +GM V G
Sbjct: 1106 FSLLGWV-PQLGTSAEDQPR--FAGNLSGRFESRWTTVKVQASTS---IMLQGMEDLVFG 1159
Query: 1228 VWVAHGEGRFTVADGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRD 1287
+ V HGEGR + +++ + ++G + YVDD+G+ TE YP+NPNGS +GLAG+ S D
Sbjct: 1160 IHVDHGEGRLLFPNADIMEHVKEHGMTPMVYVDDEGEATEQYPLNPNGSAEGLAGLCSAD 1219
Query: 1288 GRHIAMMPHPERCVLRWQCPAPCPTVTNPSVRNSQASPWLRLFQNAYSWAINH 1340
GRH+A+MPHPERC L WQ ++ + SPW ++F+NAY W +++
Sbjct: 1220 GRHLALMPHPERCFLPWQM-----HYLPEEMKELEVSPWFQMFKNAYDWCMSN 1267
>UniRef50_Q60B11 Cluster: Phosphoribosylformylglycinamidine synthase;
n=10; Proteobacteria|Rep:
Phosphoribosylformylglycinamidine synthase -
Methylococcus capsulatus
Length = 1288
Score = 665 bits (1643), Expect = 0.0
Identities = 442/1349 (32%), Positives = 686/1349 (50%), Gaps = 95/1349 (7%)
Query: 11 AFSLHKTNEILQKLKFVDSDIKDLSTELCYHVELAEGCEYLNINQIKVLKWLLS-SPLQP 69
A S+ + + +L L+ V ++ + + LA G + + + ++L+ +L+ P++
Sbjct: 10 ALSMFRASRLLASLRGVAPAVRKVDARFVHFAALARGLDDV---EHRLLRQVLNHGPVES 66
Query: 70 QAVRNETIFKSNDNSQLLIEIGPRFNFSTADSSNSVQICESVGLRDVVRLEVSTRYLITF 129
+ +ET+ + PR + SS + +I GL V R+E Y +
Sbjct: 67 ETEASETLL-----------VTPRLGTISPWSSKATEIVRRCGLDAVCRVERGIAYALQL 115
Query: 130 GKQKNVTEKHFENLAAVLHDRMTQCVYTKDNLPRKSFNEGLPKDLEPWFVVPLQEQGISA 189
+ + ++ E + A+LHDRMTQ V ++ F + P EP VPL ++G A
Sbjct: 116 DGELSAAQR--EAVRALLHDRMTQTVLSRGQ-EEMLFRQREP---EPLQYVPLMQEGRWA 169
Query: 190 MRKVNDKLGLAFDTWDMEFYMDLFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLD 249
+ K N LGLA +++ Y++ + R+P+ +EL AQ+NSEH RH F + +D
Sbjct: 170 LVKANAALGLALSEDELD-YLEQSYRAMSRNPSDIELMMFAQANSEHCRHKIFNAQWRID 228
Query: 250 GKEINESLIDMVASTQKTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRGPSQVIQ--KKT 307
G+ +++L M+ T + S + + DN++ I+G + +L +R P ++
Sbjct: 229 GEAQDQTLFGMIRHTSQASPEGIISAYSDNAAVIRGARAEVL----LRDPGGFAYGYREE 284
Query: 308 ESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGY 367
+ ++ ETHN PTA++PF GA TG GG IRD GRG H+ AG G++V +L IP +
Sbjct: 285 PAHLVMKVETHNHPTAISPFPGAATGVGGEIRDEGATGRGSHSKAGLCGFAVSHLRIPDF 344
Query: 368 DLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTR-EE 426
PWE G P A+PLQI++E G + + N+FG P + G+ +++ D
Sbjct: 345 IQPWET-GSGRPGRIASPLQIMLEGPIGGAAFNNEFGRPNLCGYFRTFQQLAPDGASLYG 403
Query: 427 FVKPIMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDH 486
+ KPIM +GG+G + + K++ G +V A D
Sbjct: 404 YHKPIMLAGGMGNIREVNLGKSEIPPGAPIV-VLGGPAMLIGLGGGAASSVASGESAED- 461
Query: 487 ALDFGAVQRGDAEMGNRLNRVVRGCLE-SDVNPVESIHDQGAGGNGNVLKELVEPEG--A 543
LDF +VQR + EM R V+ C+ + NP+ SIHD GAGG N + EL+ G
Sbjct: 462 -LDFASVQRDNPEMERRCQEVIDHCVALGEDNPILSIHDVGAGGLSNAVPELIHDSGRGG 520
Query: 544 VVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGEVTGD 603
++ +P ++ ++LW E QE L + +C RERCP + +G T D
Sbjct: 521 RFELRDIPSAEPGLSPMQLWCNESQERYVLALRPERLERFQALCERERCPFAVIGHATAD 580
Query: 604 GYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKRTKLPLS 663
+ ++ D +F + P + + + G PR D+ PL
Sbjct: 581 EDL-VVNDL---RFANH------------PVAIPMSLLFGKPPRMLRDVARLPAATKPLD 624
Query: 664 FPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALS 723
F + A+ RVL L VA K +L + DR V GLVA+ Q VGP P+AD A+
Sbjct: 625 FA-GFDWRDAVKRVLSLPAVADKSFLIHIGDRSVGGLVARDQLVGPWQVPVADVAVTVSG 683
Query: 724 YYDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWA-GK 782
+ + G A ++G ++ ++D A R+++GEALTN++ A I+ L DVK S NWM A G
Sbjct: 684 FRAVTGEAMALGERSPIAVIDAPASGRMAVGEALTNILAAPIASLGDVKLSANWMAAAGA 743
Query: 783 TGVEXXXXXXXXXXXXXXMRALGVAVDGGKDSLSMCA--HVAGEKVK--SPGTLVVSTYA 838
G + ALGVA+ GKDSLSM +G+++ SP +L+VS +A
Sbjct: 744 PGEDARLFDTVRAVSLELCPALGVAIPVGKDSLSMRTVWRESGKEMAMISPLSLIVSAFA 803
Query: 839 PCPDITVKIEPALKEENSA--LVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXK 896
P D+ + P L+ + A LV + G+ RLGGSALAQ Y Q+G+ +
Sbjct: 804 PVTDVRRTLTPELRLDGGASVLVLIDLGQGRNRLGGSALAQVYGQMGETCPDLDDPALFR 863
Query: 897 SLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNE 956
+ F Q L + +++ HD S+GG T +EM G++LH++ + P+ A F E
Sbjct: 864 AFFGAVQSLSSDGLILAYHDRSDGGLFVTAVEMAFAARTGIDLHLDHLGD--PVAAAFAE 921
Query: 957 ELGIVLEVSKNDLPYVLSEYNNNGVGAQHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVF 1016
ELG V++V+ +DLP V+ + G+GA G DS++V++ G+ + ++
Sbjct: 922 ELGAVIQVASDDLPAVMVRLEDAGLGACS-RVVGAPRSDSRIVVHHGGMPIFGASRAELQ 980
Query: 1017 RMWEETSYRLECLQANTDCVLQEWKVL--EKRKGATYNVTFDPTAAV----IKTKSIKVA 1070
+W ETSYR++ L+ N DC Q+++ L + G ++FDP V + ++A
Sbjct: 981 GIWSETSYRMQALRDNPDCARQQFESLFDDGDPGLHAKLSFDPNTDVAAPYLNLSRPRMA 1040
Query: 1071 VLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSA 1130
+LRE+G+NG EM A+ A F DV MSDL +I L F+G+ GGFSY D LG+
Sbjct: 1041 ILREQGVNGHMEMAAAFDAAGFACVDVHMSDLAEGRIGLADFRGLAACGGFSYGDVLGAG 1100
Query: 1131 KGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQIFL 1190
GWA IL++ L +F F R+DTF LGVCNGCQ+++ L + P G+ F+
Sbjct: 1101 GGWAKSILYNARLRDEFVAFFRREDTFGLGVCNGCQMLSQLHELIP-----GAENWPRFV 1155
Query: 1191 DHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLYK 1250
N SE++E R + V+I + + ++F GM GS L V V+HGEGR G+
Sbjct: 1156 -RNRSEQYEARVAMVEIQPSRS---IFFDGMTGSRLPVVVSHGEGRVEYRPGT-----GN 1206
Query: 1251 NGQ-VAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCPAP 1309
GQ VAV +VD+ + TE YP NPNGSP G+ G+ + DGR MMPHPERC
Sbjct: 1207 GGQLVAVAFVDNYDRITEAYPFNPNGSPRGITGLTTPDGRFTIMMPHPERCF-------- 1258
Query: 1310 CPTVTNP-SVRN-SQASPWLRLFQNAYSW 1336
TV N R+ + PW+R+F+NA W
Sbjct: 1259 -RTVQNSWRPRDWGEYGPWMRMFRNARRW 1286
>UniRef50_Q87RW0 Cluster: Phosphoribosylformylglycinamidine synthase;
n=78; Bacteria|Rep: Phosphoribosylformylglycinamidine
synthase - Vibrio parahaemolyticus
Length = 1302
Score = 663 bits (1637), Expect = 0.0
Identities = 433/1274 (33%), Positives = 651/1274 (51%), Gaps = 74/1274 (5%)
Query: 86 LLIEIGPRFNFSTADSSNSVQICESVGLRDVVRLEVSTRYLITFGKQKNVTEKHFENLAA 145
LL+ + PR + SS S I + GL V RLE T Y + ++E + + A
Sbjct: 72 LLLLVTPRPGTISPWSSKSTDIAINCGLDTVKRLERGTAYYVE--SSVVLSEAQVDAVKA 129
Query: 146 VLHDRMTQCVYTKDNLPRKSFNEGLPKDLEPWFVVPLQEQGISAMRKVNDKLGLAFDTWD 205
++HDRM + V+T+ F PK P V + G A+ + N LGLA +
Sbjct: 130 LIHDRMMETVFTELEAASALFTVAEPK---PVAHVDILAGGRLALEEANVSLGLALAEDE 186
Query: 206 MEFYMDLFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLIDMVASTQ 265
+++ ++ F KL R+P +EL AQ+NSEH RH F +DG + +SL M+ +T
Sbjct: 187 IDYLVENFT-KLGRNPNDIELMMFAQANSEHCRHKIFNADWTIDGVDQEKSLFKMIKNTF 245
Query: 266 KTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRGPSQVIQKKTESDIIFTAETHNMPTAVA 325
+T+ ++ + + DN++ + G + P Q ++ I+ ETHN PTA++
Sbjct: 246 ETTPDHVLSAYKDNAAVMTGSKVGRFFPDPKS--RQYTYHHEDAHILMKVETHNHPTAIS 303
Query: 326 PFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATP 385
P+ GA+TG+GG IRD G GG AG G++ NL IPG++ PW E + P
Sbjct: 304 PWPGASTGSGGEIRDEGATGIGGKPKAGLVGFTTSNLRIPGFEQPW-ETDFGKPGRIVNA 362
Query: 386 LQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTREE---FVKPIMFSGGIGYMPH 442
L I++E G + + N+FG P + G+ ++Y K + EE + KPIM +GG+G +
Sbjct: 363 LDIMLEGPLGGAAFNNEFGRPNLLGYFRTYEEKVTSHAGEEVRGYHKPIMIAGGMGNIRD 422
Query: 443 SMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGN 502
++K + G L+ A D LDF +VQR + EM
Sbjct: 423 EHVQKKEIPVGASLI-VLGGPAMNIGLGGGAASSMASGQSAED--LDFASVQRENPEMER 479
Query: 503 RLNRVVRGCLE-SDVNPVESIHDQGAGGNGNVLKELVE--PEGAVVFTKEFQLGDPTITT 559
R V+ C + + NP+ IHD GAGG N L EL + G ++ + +++
Sbjct: 480 RCQEVIDRCWQLGEENPIAFIHDVGAGGISNALPELCDDGERGGKFQLRDVPNDELSMSP 539
Query: 560 LELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLD 619
LE+W E QE L + N + IC+RER P + VG T + +++L EDS+ +
Sbjct: 540 LEIWCNESQERYVLAVAPENMEAFDAICKRERAPYAVVGVATEERHLTL-EDSHFD---- 594
Query: 620 RSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKRTKLPLSFPKDITVKSALDRVLR 679
P D+ ++ +LG P+ + T K P I + A DRVLR
Sbjct: 595 -----------NTPIDMPMDILLGKTPKMHREATTLK-VDSPAIARDGIEIDEAADRVLR 642
Query: 680 LVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALSYYDLVGSATSIGTQNI 739
L VA K +L DR VTGLVA+ Q VGP P+A+CA+ A SY G A S+G +
Sbjct: 643 LPTVAEKTFLITIGDRSVTGLVARDQMVGPWQVPVANCAVTAASYDTYHGEAMSMGERTP 702
Query: 740 KGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMW-AGKTGVEXXXXXXXXXXXX 798
LLD A ARL++GE+LTN+ I +++ +K S NWM AG G +
Sbjct: 703 VALLDFGASARLAVGESLTNIAATDIGDIKRIKLSANWMSPAGHPGEDAGLYEAVKAVGE 762
Query: 799 XXMRALGVAVDGGKDSLSMCA----HVAGEKVKSPGTLVVSTYAPCPDITVKIEPALKEE 854
ALG+ + GKDS+SM + ++V SP +LV++ + D+ + P L+
Sbjct: 763 ELCPALGLTIPVGKDSMSMKTKWEENGESKEVTSPLSLVITAFGRVEDVRKTVTPQLRTS 822
Query: 855 -------NSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLK 907
+++LV + GK RLG +ALAQ YKQLGD K F Q L++
Sbjct: 823 DTLEGLGDTSLVLVDLGNGKNRLGATALAQVYKQLGDKPADVDNAEQLKGFFDAMQNLVR 882
Query: 908 EKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGIVLEVSKN 967
KL++ HD +GG T+ EM G G+ + + LFNEELG V++V +
Sbjct: 883 NDKLLAYHDKGDGGLFVTLAEMAFAGHCGVKADI-AELGEDALAVLFNEELGAVVQVKND 941
Query: 968 DLPYVLSEYNNNGVGA-QHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFRMWEETSYRL 1026
DL VLS NG+ A H+ G V VL ++ +W ET++++
Sbjct: 942 DLDSVLSTLAANGLEACSHV--IGSVEASDDFVFTSGDDVVLKRSRTELRVIWAETTHKM 999
Query: 1027 ECLQANTDCVLQEWKVLEKR--KGATYNVTFD---PTAA--VIKTKSIKVAVLREEGING 1079
+ L+ N C QE++ + G +++FD AA + K K+A+LRE+G+N
Sbjct: 1000 QALRDNPACADQEFEAKKDNTDPGLNVSLSFDVNEDIAAPYIAKGAKPKMAILREQGVNS 1059
Query: 1080 DREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILF 1139
EM A+ A F+ D+ MSD+ + LD +QG+V GGFSY D LG+ +GWA ILF
Sbjct: 1060 HVEMAAAFDRAGFEATDIHMSDILTGQAVLDEYQGLVACGGFSYGDVLGAGEGWAKSILF 1119
Query: 1140 SESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQIFLDHNSSERFE 1199
+ QF F +R++TFSLGVCNGCQ+++ L + P G++ F+ N SERFE
Sbjct: 1120 NAQAREQFQAFFNREETFSLGVCNGCQMLSNLKELIP-----GADLWPRFV-RNESERFE 1173
Query: 1200 CRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLYKNGQVAVQYV 1259
R+S V++ ++++ V+F GM GS + + V+HGEGR V DG L+ + +G VA++YV
Sbjct: 1174 ARFSLVEVQKSDS---VFFDGMAGSRMPIAVSHGEGRVEVRDGEHLNAIEASGTVALRYV 1230
Query: 1260 DDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCPAPCPTVTNPSVR 1319
D++G PT+ YP NPNGSP+ + G+ + DGR MMPHPER V R + P
Sbjct: 1231 DNNGNPTQQYPNNPNGSPNAITGLTTADGRVTIMMPHPER-VFRTVANSWAPEGW----- 1284
Query: 1320 NSQASPWLRLFQNA 1333
+ W+R+FQNA
Sbjct: 1285 -GENGAWMRMFQNA 1297
>UniRef50_Q6LU24 Cluster: Phosphoribosylformylglycinamidine synthase;
n=103; Proteobacteria|Rep:
Phosphoribosylformylglycinamidine synthase -
Photobacterium profundum (Photobacterium sp. (strain
SS9))
Length = 1322
Score = 662 bits (1635), Expect = 0.0
Identities = 454/1379 (32%), Positives = 705/1379 (51%), Gaps = 108/1379 (7%)
Query: 1 MSIVRFFSTEAFSLHKTNEILQKLKFVDSDIKDLSTELCYHVELAEGCEYLNINQIKVLK 60
M I+R + A S + N++L++ + +D + + E + +++ LN ++ L
Sbjct: 1 MEILR--GSPALSEFRVNKLLERCRELDLPVSGIYAEFMHFADVSAP---LNSDEQSKLA 55
Query: 61 WLLSSPLQPQAVRNETIFKSNDNSQLLIEIGPRFNFSTADSSNSVQICESVGLRDVVRLE 120
LL+ TI + +L+ + PR + SS S I ++ L +V RLE
Sbjct: 56 SLLTY--------GPTIAEHEPTGTMLL-VTPRPGTISPWSSKSTDIAQNCALGNVKRLE 106
Query: 121 VSTRYLITFGKQKNVTEKHFENLAAVLHDRMTQCVYTKDNLPRKSFNEGLPKDLEPWFVV 180
T Y + ++T +L A++HDRM + V+T + F + P ++ V
Sbjct: 107 RGTAYYVEV--TADLTNAQLTDLKALIHDRMMEVVFTDVDSAAALFTQAEPAPVQS---V 161
Query: 181 PLQEQGISAMRKVNDKLGLAFDTWDMEFYMDLFVNKLKRDPTSVELFDLAQSNSEHSRHW 240
+ G A+ N KLGLA ++++ ++ F L R+P +EL AQ+NSEH RH
Sbjct: 162 DILVGGRKALEDANLKLGLALAEDEIDYLVENFT-MLGRNPNDIELMMFAQANSEHCRHK 220
Query: 241 FFKGKLVLDGKEINESLIDMVASTQKTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRGPS 300
F +DG E +SL M+ +T + ++ + + + DN++ ++G + P
Sbjct: 221 IFNADWTIDGVEQEKSLFKMIKNTYEKNHEHVLSAYKDNAAVMEGSEVGRFFPNPES--R 278
Query: 301 QVIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVG 360
Q + + I+ ETHN PTA++P+ GA+TG+GG IRD G GG AG G++V
Sbjct: 279 QYNYHQEAAHILMKVETHNHPTAISPWPGASTGSGGEIRDEGATGLGGKPKAGLVGFTVS 338
Query: 361 NLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNA 420
NL +PG++ PWE + P L+I++E G + + N+FG P + G+ ++Y K
Sbjct: 339 NLRVPGFEQPWETD-FGKPGRIVNALEIMLEGPLGGAAFNNEFGRPNLLGYFRTYEEKVT 397
Query: 421 DNTREE---FVKPIMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXX 477
+ EE + KPIM +GG+G + ++K + G L+
Sbjct: 398 SHNGEEIRGYHKPIMIAGGMGNIRADHVQKKEIPVGAKLI-VLGGPAMNIGLGGGAASSM 456
Query: 478 XXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLE-SDVNPVESIHDQGAGGNGNVLKE 536
A D LDF +VQR + EM R V+ C + D NP+ IHD GAGG N L E
Sbjct: 457 ASGQSAED--LDFASVQRENPEMERRCQEVIDRCWQMGDANPIAFIHDVGAGGISNALPE 514
Query: 537 LVEP--EGAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPV 594
LV+ G + +P ++ LE+W E QE + + N + E IC+RER P
Sbjct: 515 LVDDGERGGKFQLRNVPNDEPGMSPLEIWCNESQERYVMAVAPENLAVFEAICKRERAPF 574
Query: 595 SFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQT 654
+ VGE T + +++L ED + + P D+ ++ +LG P+ D +T
Sbjct: 575 AVVGEATEERHLTL-EDEHFDN---------------TPIDMPMDILLGKAPKMHRDAKT 618
Query: 655 EKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPL 714
K + I +++A RVLRL VA K +L DR VTGLVA+ Q VGP P+
Sbjct: 619 LKVEGQAID-RSGIELEAATQRVLRLPAVAEKTFLITIGDRSVTGLVARDQMVGPWQVPV 677
Query: 715 ADCAIIALSYYDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCS 774
A+CA+ A SY G A S+G + LLD A ARL++GEA+TN+ A I +++ + S
Sbjct: 678 ANCAVTAASYDTYHGEAMSMGERTPVALLDFGASARLAVGEAITNIASADIGDMKRINLS 737
Query: 775 GNWMW-AGKTGVEXXXXXXXXXXXXXXMRALGVAVDGGKDSLSMCA--HVAGE--KVKSP 829
NWM AG G + ALG+ + GKDS+SM GE +V SP
Sbjct: 738 ANWMSPAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSMKTKWEQDGEQKEVTSP 797
Query: 830 GTLVVSTYAPCPDITVKIEPALKEE--NSALVHAPVSPGKYRLGGSALAQCYKQLGDNXX 887
+LV++ + D+ + P L+ + S+L+ + G+ RLG +ALAQ YKQLGD
Sbjct: 798 LSLVITAFGRVEDVRKTVTPQLRTDKGESSLILIDLGCGQNRLGATALAQVYKQLGDKPA 857
Query: 888 XXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVA--- 944
K F Q L++++K+++ HD +GG T+ EM G G+ + +N +
Sbjct: 858 DVDNPELLKGFFYAVQALVRDEKVLAYHDRGDGGLYVTLAEMAFAGHTGVEVDINTSESD 917
Query: 945 ANVSPIEALFNEELGIVLEVSKNDLPYVLSEYNNNGVGA-QHIGYTGKYGMDSQVVINLN 1003
A + LFNEELG VL+V DL V S +G+ A H+ T +D VV N
Sbjct: 918 ACDDVLAMLFNEELGAVLQVRTEDLDTVKSVLAEHGLTACSHVIGT---VVDEDVVRIWN 974
Query: 1004 GVN-VLDTVLIDVFRMWEETSYRLECLQANTDCVLQEWKVLEKRK--GATYNVTFD---- 1056
G + VL+ D+ +W ET+Y+++ ++ N LQE++ + G + +TFD
Sbjct: 975 GNDRVLEQSRTDLRTVWAETTYQMQAMRDNPAGALQEFEAKKDNSDPGLSAQLTFDINED 1034
Query: 1057 ----------------PTAAVIKTKSI------KVAVLREEGINGDREMIASLMLANFDV 1094
A+V+ +I ++A+LRE+G+N EM A+ A F+
Sbjct: 1035 VAAPFIAAPFITKAPKTGASVVNAPAINLGAKPQMAILREQGVNSHVEMAAAFDRAGFEA 1094
Query: 1095 FDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKDRK 1154
DV MSD+ + + L+ F G+V GGFSY D LG+ +GWA +LF+ QF F R
Sbjct: 1095 TDVHMSDILSGNVQLEGFNGLVACGGFSYGDVLGAGEGWAKSVLFNNIARDQFEAFFKRN 1154
Query: 1155 DTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQIFLDHNSSERFECRWSAVKIHENENKE 1214
DTFSLGVCNGCQ+M+ L + P GS+ F+ N SERFE R+S V++ ++++
Sbjct: 1155 DTFSLGVCNGCQMMSNLSELIP-----GSDLWPRFV-RNESERFEARFSLVEVQKSDS-- 1206
Query: 1215 DVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPN 1274
++F M GS + + V+HGEGR V +G L+ + ++G VA++Y+D+ G T+ YP NPN
Sbjct: 1207 -LFFNEMAGSRMPIAVSHGEGRVEVRNGEHLNAIEQSGTVALRYLDNFGNVTQNYPANPN 1265
Query: 1275 GSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCPAPCPTVTNPSVRNSQASPWLRLFQNA 1333
GSP+G+ G+ + DGR MMPHPER V R + P N + SPW+R+F+NA
Sbjct: 1266 GSPNGITGLTTMDGRVTIMMPHPER-VFRTVANSWHPDDWN------ENSPWMRMFRNA 1317
>UniRef50_A6EP05 Cluster: Phosphoribosylformylglycinamidine synthase;
n=2; Bacteroidetes|Rep: Phosphoribosylformylglycinamidine
synthase - unidentified eubacterium SCB49
Length = 1256
Score = 656 bits (1622), Expect = 0.0
Identities = 427/1256 (33%), Positives = 638/1256 (50%), Gaps = 99/1256 (7%)
Query: 90 IGPRFNFSTADSSNSVQICESVGLRDVVRLEVSTRYLITFGKQKNVTEKHFENLAAVLHD 149
IGPR T S+N+V+I +++G+ ++R+E + T +++ + + +
Sbjct: 87 IGPRAAMITPWSTNAVEITQNMGIEGIIRIEEF--------HNASETPDNYDPMLSQKYK 138
Query: 150 RMTQCVYTKDNLPRKSFNEGLPKDLEPWFVVPLQEQGISAMRKVNDKLGLAFDTWDMEFY 209
+ Q ++T + +EP ++ +++ ISA K GLA + ++ Y
Sbjct: 139 ELGQEMFTIN--------------IEPEPILDIED--ISAFNKAE---GLALNDEEV-VY 178
Query: 210 MDLFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLIDMVASTQKTSN 269
++ KL+R T E+F +Q+NSEH RH F G ++DG+E+ SL ++ T +
Sbjct: 179 LENLSKKLERPLTDSEVFAFSQANSEHCRHKIFNGTFIIDGEEMPSSLFKLIKKTSSENP 238
Query: 270 NNNVIKFGDNSSAIKGFQHTILRPTNVRGPSQVIQKKTESDIIFTAETHNMPTAVAPFSG 329
N+ V + DN + +KG + T P + P + +S I AETHN PT V PF+G
Sbjct: 239 NDIVSAYKDNVAFVKGPKATQFAPASPDKPDYYKNTEFDSVISLKAETHNFPTTVEPFNG 298
Query: 330 ATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQII 389
A TG+GG IRD G+G +AGTA Y + + PWE+ + TPL I+
Sbjct: 299 AATGSGGEIRDRLAGGKGSLPLAGTAVYMTSYSRL-NDEKPWEKTMKPRDWLYQTPLDIL 357
Query: 390 IEASNGASDYGNKFGEPVISGFVQSYGLKNADNTRE-EFVKPIMFSGGIGYMPHSMIKKN 448
I+ASNGASD+GNKFG+P+I+G V ++ ++ D+ R+ F K IM +GGIGY K+
Sbjct: 358 IKASNGASDFGNKFGQPLITGSVLTF--EHQDDARKLGFDKVIMMAGGIGYGKADQALKD 415
Query: 449 KPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVV 508
P G +V + ++ A+QR + EM R V
Sbjct: 416 TPKTGDKVVILGGENYRIGMGGAAVSSADTGEFSS---GIELNAIQRSNPEMQKRAANAV 472
Query: 509 RGCLESDVNPVESIHDQGAGGNGNVLKELVEPEGAVVFTKEFQLGDPTITTLELWGAEYQ 568
RG +ESD+NP+ SIHD GAGG+ N L ELVE G ++ + +GDPT++ E+ G E Q
Sbjct: 473 RGMVESDINPIVSIHDHGAGGHLNCLSELVEDTGGMIDLDKLPVGDPTLSAKEIIGNESQ 532
Query: 569 ENDALLCSKANRHILEEICRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLES 628
E L+ + + L+ + RER P+ VGEVTGD +F K ++
Sbjct: 533 ERMGLVIGEDDVDTLKRVADRERSPMYEVGEVTGD-----------HRF-----TFKSKT 576
Query: 629 KSKLPYDLHLEAVLGNMPRKTFDLQTEKRTKLPLSFPKDIT-VKSALDRVLRLVNVASKR 687
P D LE G+ P+ + +T R S+ D++ +K+ + +VL+L VA K
Sbjct: 577 TGATPMDYALEDFFGSSPKTIMNDKTVTRDYTDASY--DVSEIKNYVSQVLQLEAVACKD 634
Query: 688 YLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALSYYDLVGSATSIGTQNIKGLLDPAA 747
+LTNKVDRCVTG VA+QQC GPL PL +C ++AL Y + G ATSIG I GL+DP A
Sbjct: 635 WLTNKVDRCVTGKVAKQQCAGPLQLPLNNCGVMALDYNGINGVATSIGHSPISGLIDPVA 694
Query: 748 GARLSLGEALTNLVFAGISE-LEDVKCSGNWMWAGKTGVEXXXXXXXXXXXXXXMRALGV 806
GAR S+ E+LTN+++A + L+ + S NWMW E LGV
Sbjct: 695 GARNSITESLTNIIWAPLENGLKSISLSANWMWPCNNEGEDARLYQAVKAVSEFSIDLGV 754
Query: 807 AVDGGKDSLSMCAHVAGEKVKSPGTLVVSTYAPCPDITVKIEPALKEENSALVHAPVSPG 866
V GKDSLSM E+V SPGT+++S A C +I +EP + L + +S
Sbjct: 755 NVPTGKDSLSMKQKYKNEEVISPGTVIISAGAHCSNIKQVVEPVAQLGKGNLYYINISQD 814
Query: 867 KYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTV 926
++LGGS+ Q +G+ K++F Q L+K+ ++++GHD++ GG ITT+
Sbjct: 815 DFKLGGSSFGQILSAIGNQAPTVKSAAYVKTVFNTIQALIKDNQIVAGHDVASGGLITTL 874
Query: 927 LEMGIGGVR-GLNLHVNVAANVSPIEALFNEELGIVLEVSKNDLPYVLSEYNNNGVGAQH 985
LE+ G G L + + ++ LF E GIV++ + N + N N + +
Sbjct: 875 LELFFGNTNTGAKLDLTGLGD-DLVKILFAENCGIVIQAADNTI--FEKALNANDISFHN 931
Query: 986 IGYTGKYGMDSQVVINLNGVNVLDTVLIDVFRMWEETSYRLECLQANTDCVLQEWKVLEK 1045
+G + + + I L +V + ++ W ETSY L+ Q+ + E
Sbjct: 932 LGEVTE---SNALEITLGSQDV-QFDIAEMRDTWYETSYLLDTKQSGNQAKAR----FEN 983
Query: 1046 RKGATYNVTF-----DPTAAVIKTKSIKVAVLREEGINGDREMIASLMLANFDVFDVTMS 1100
K N TF K + IK A++RE+G N +REM ++ LA FDV DV M+
Sbjct: 984 YKNQPLNFTFPKQFTGKLPEAPKGERIKAAIIREKGSNSEREMANAMYLAGFDVKDVHMT 1043
Query: 1101 DLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLG 1160
DL + + TL+ + + GGFS +D LGSAKGWA L++E + F + DT SLG
Sbjct: 1044 DLISGRETLEDIKFIAAVGGFSNSDVLGSAKGWAGAFLYNEKANKALKDFFAKDDTLSLG 1103
Query: 1161 VCNGCQLMAMLGWVDPDSNSKGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRG 1220
VCNGCQL LG + P+ K + HN S +FEC +++VKI EN + V
Sbjct: 1104 VCNGCQLFVELGLLTPEDTEKPK------MLHNDSGKFECSFTSVKIQENNS---VMLSS 1154
Query: 1221 MGGSVLGVWVAHGEGRFTVADGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGL 1280
+ GS LG+W AHGEG+F+ K + + +Y D +P NPNGS
Sbjct: 1155 LAGSTLGIWAAHGEGKFS------FPKEENHYNIVGKYGYD------AFPSNPNGSDFNT 1202
Query: 1281 AGVRSRDGRHIAMMPHPERCVLRWQCPAPCPTVTNPSVRNSQASPWLRLFQNAYSW 1336
A + + GRH+ MMPH ER W PS N +PWL F NA W
Sbjct: 1203 AMMTDKTGRHLVMMPHLERSTFPWNWG------HYPSDSNDVVTPWLEGFVNARKW 1252
>UniRef50_Q5QWY0 Cluster: Phosphoribosylformylglycinamidine synthase;
n=60; Proteobacteria|Rep:
Phosphoribosylformylglycinamidine synthase - Idiomarina
loihiensis
Length = 1295
Score = 654 bits (1615), Expect = 0.0
Identities = 446/1345 (33%), Positives = 683/1345 (50%), Gaps = 85/1345 (6%)
Query: 11 AFSLHKTNEILQKLKFVDSDIKDLSTELCYHVELAEGCEYLNINQIKVLKWLLSSPLQPQ 70
A S KT + L++LK +K+L E + V+L E + ++ +++ L P P
Sbjct: 9 ALSAFKTTKQLEQLKQAGIPVKELYAEYQHFVDLHN--ELSDEHRSVLVQLLKYGPEMP- 65
Query: 71 AVRNETIFKSNDNSQLLIEIGPRFNFSTADSSNSVQICESVGLRDVVRLEVSTRYLITFG 130
+++ L+ + PR + +S + I + GL+ + R+E + F
Sbjct: 66 ---------AHEPQGALVLVTPRIGTISPWASKATDIAHNCGLKSIHRVERG----VAFY 112
Query: 131 KQKNVTEKHFENLAAVLHDRMTQCVYTKDNLPRKSFNEGLPKDLEPWFVVPLQEQGISAM 190
Q +++ + + A +LHDRMT+ V N ++ F P+ L V + G A+
Sbjct: 113 LQGDLSAEELKQAALLLHDRMTESVLYDMNDAQQLFRSQEPQPLSS---VDILAGGREAL 169
Query: 191 RKVNDKLGLAFDTWDMEFYMDLFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDG 250
+ N LGLA ++++ ++ F KL R+P +EL+ AQ+NSEH RH F +DG
Sbjct: 170 AQANISLGLALADDEIDYLVENF-RKLDRNPNDIELYMFAQANSEHCRHKIFNADWTIDG 228
Query: 251 KEINESLIDMVASTQKTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRGPSQVIQKKTESD 310
E +SL M+ +T +T+ + + + DN++ ++G + P P + +
Sbjct: 229 AEQPKSLFKMIKNTFETTPDYVLSAYKDNAAVMEGHEAGRFYPQ----PDSMSYGYSHEP 284
Query: 311 --IIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYD 368
I+ ETHN PTA++P+ GA TG+GG IRD G G AG G+SV NL+IPG+
Sbjct: 285 VHILMKVETHNHPTAISPYPGAATGSGGEIRDEGATGVGSKPKAGLVGFSVSNLNIPGFK 344
Query: 369 LPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSY-GLKNADNTREE- 426
PWEE + P+ + L I++E G + + N+FG P ++G+ ++Y ++ N RE
Sbjct: 345 QPWEE-NYGKPARIVSALDIMLEGPLGGAAFNNEFGRPALTGYFRTYEQTVDSHNGRETR 403
Query: 427 -FVKPIMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARD 485
+ KPIM +GG+G + + ++K G LV D
Sbjct: 404 GYHKPIMIAGGLGNIREAHVQKGDIPVGAKLV-VLGGPAMNIGLGGGAASSMASGESTED 462
Query: 486 HALDFGAVQRGDAEMGNRLNRVVRGCLESDV-NPVESIHDQGAGGNGNVLKELVEP--EG 542
LDF +VQR + EM R V+ C + NP+ IHD GAGG N + ELV G
Sbjct: 463 --LDFASVQRENPEMERRCQEVIDRCWQLGADNPIAFIHDVGAGGLSNAMPELVSDGGRG 520
Query: 543 AVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGEVTG 602
+E +P +T LE+W E QE + + N E +C RER + +GE T
Sbjct: 521 GRFELREIPNDEPGMTPLEIWCNESQERYVIAIAPENLARFEALCERERAEYAVIGEAT- 579
Query: 603 DGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKRTKLPL 662
+ L+ D+ KF S P DL L+ +LG P+ D+ + PL
Sbjct: 580 EELTILLNDA---KF------------SNQPIDLSLDVLLGKPPKMHRDVARLQTEGTPL 624
Query: 663 SFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIAL 722
+ + A DR+LRL +A K +L DR VTGLVA+ Q VGP P+AD A+ A
Sbjct: 625 HL-EAADLNDAADRLLRLPAIAEKTFLITIGDRSVTGLVARDQMVGPWQIPVADVAVTAS 683
Query: 723 SYYDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMW-AG 781
SY G A ++G + LL+ A AR+++ E+LTN+ A I +L+ +K S NWM AG
Sbjct: 684 SYDSYHGEAMAMGERTPLALLNFGASARMAVAESLTNIAAADIGDLKRIKLSANWMCAAG 743
Query: 782 KTGVEXXXXXXXXXXXXXXMRALGVAVDGGKDSLSMCA--HVAGE--KVKSPGTLVVSTY 837
G + LG+ + GKDS+SM GE V +P +LV++ +
Sbjct: 744 HPGEDAGLYEAVKAVGEELCPELGITIPVGKDSMSMKTQWQQDGEDKAVTAPMSLVITAF 803
Query: 838 APCPDITVKIEPALKEE--NSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXX 895
DI + P L+ + S LV + G+ RLGGSALAQ Y+QLG +
Sbjct: 804 GRVNDIRSTLTPQLRTDKGQSHLVLIDLGKGQNRLGGSALAQVYQQLGQHTPDLDDTETF 863
Query: 896 KSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFN 955
K+ F TQ+L+ E +L++ HD S+GG TTV EM G G + ++ + LFN
Sbjct: 864 KAFFNTTQQLVTEGRLLAYHDRSDGGLFTTVAEMAFAGNCGAKVALDELGE-DNLATLFN 922
Query: 956 EELGIVLEVSKNDLPYVLSEYNNNGVGAQHIGYTGKYGMDSQVVINLNGVNVLDTVLIDV 1015
EELG V++VS V+ Y G+G + G+ + +V + NVL
Sbjct: 923 EELGAVIQVSDEQYQKVMDAYKTAGLG-DCVKRIGEPTHEDAIVFTRDEQNVLAQSRTHW 981
Query: 1016 FRMWEETSYRLECLQANTDCVLQEWKVLEK--RKGATYNVTFDPT---AAVIKTKSI--K 1068
+W ET++ ++ L+ N C +E+++ ++ G ++TFDP+ AA K + K
Sbjct: 982 RTVWAETTHHMQRLRDNPVCADEEFRLKQRADNPGLLADLTFDPSEDIAAPYIAKGVAPK 1041
Query: 1069 VAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLG 1128
VA+LRE+G+N EM A+ A F+ DV MSD+ +++L+ Q + GGFSY D LG
Sbjct: 1042 VAILREQGVNSHYEMAAAFDRAGFEAVDVHMSDILAGRVSLEDMQALAACGGFSYGDVLG 1101
Query: 1129 SAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQI 1188
+ +GWA ILF++ QF F R DT +LGVCNGCQ+++ L + P G+
Sbjct: 1102 AGEGWAKSILFNDRAREQFEAFFKRNDTLALGVCNGCQMLSTLKQLIP-----GTEHWPR 1156
Query: 1189 FLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKL 1248
F+ N SERFE R+S V++ E+++ ++ M GS + + V+HGEGR A+ +L
Sbjct: 1157 FVT-NRSERFEARFSLVEVQESKS---IFLGDMAGSRMPIAVSHGEGRAEFANPQQQSQL 1212
Query: 1249 YKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCPA 1308
+N QVA++Y+D+ G+ E YP NPNGSP G+ V S DGR AMMPHPER V R +
Sbjct: 1213 EQNSQVALRYIDNWGEVAEQYPANPNGSPKGITAVTSDDGRVTAMMPHPER-VFRTVANS 1271
Query: 1309 PCPTVTNPSVRNSQASPWLRLFQNA 1333
P + SPW+R+F+NA
Sbjct: 1272 WHPD------EWGEDSPWMRMFRNA 1290
>UniRef50_A5WCV9 Cluster: Phosphoribosylformylglycinamidine synthase;
n=3; Psychrobacter|Rep: Phosphoribosylformylglycinamidine
synthase - Psychrobacter sp. PRwf-1
Length = 1341
Score = 645 bits (1593), Expect = 0.0
Identities = 447/1314 (34%), Positives = 652/1314 (49%), Gaps = 108/1314 (8%)
Query: 85 QLLIEIGPRFNFSTADSSNSVQICESVGLRDVVRLEVSTRYLITFGKQKNVTEKHFENLA 144
Q + + PRF + SS + I + L V R+E + +T + K E
Sbjct: 72 QCQVIVSPRFGTISPWSSKATDIFNNCELA-VERVERVIVFTLTGEDLPSKLPKQAEQ-- 128
Query: 145 AVLHDRMTQCVYTKDNLPRKSFNEGLPKDLEPWFVVPLQEQGISAMRKVNDKLGLAFDTW 204
+LHDRMTQ + N + F++ P L+ V + QG SA+ N + G A
Sbjct: 129 -ILHDRMTQSLVYDLNQLSQLFDDHTPASLKH---VDIIGQGRSALEAANREFGFALSVE 184
Query: 205 DMEFYMDLFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLIDMVAST 264
D+++ M + +LKR+PT VEL AQ+NSEH RH F + +DG+ +SL M+ +T
Sbjct: 185 DIDYLMQAYGEELKRNPTDVELMMFAQANSEHCRHKIFNSEWTVDGEVQPKSLFKMIRNT 244
Query: 265 QKTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRG------PSQVIQKKTES---DIIFTA 315
+ + + + DN++ ++GF+ P + SQ+ Q + DI+
Sbjct: 245 HEKNPAGILSAYKDNAAVMQGFEAERFYPLPQKELGEDVLSSQMHQYDFHNEHIDILMKV 304
Query: 316 ETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKG 375
ETHN PTA+AP++GA+TG GG IRD GRGG AG G++V +LH+P WE+ G
Sbjct: 305 ETHNHPTAIAPYAGASTGAGGEIRDEGATGRGGKPKAGLTGFNVSHLHLPDMPEKWEQSG 364
Query: 376 W----EY--PSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNT----RE 425
+Y P A+ L+I+ EA G++++ N+FG P + G+ +S+ L + N
Sbjct: 365 QFSTKDYGKPERMASSLEIMTEAPLGSANFANEFGRPNLCGYFRSFQLDTSANQDGSEMR 424
Query: 426 EFVKPIMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARD 485
+ KPIM +GG G + ++++KN +G LL+ D
Sbjct: 425 GYHKPIMIAGGYGNIKRNLVEKNSIQEGDLLIVLGGPAMQIGLGGGAASSVDSGELD--- 481
Query: 486 HALDFGAVQRGDAEMGNRLNRVVRGC------------LESDVNPVESIHDQGAGGNGNV 533
LDF +VQR +AEM R V+ C D NP+ SIHD GAGG N
Sbjct: 482 EGLDFASVQRDNAEMERRCQEVIDRCWALAGNDIEASAASKDGNPIVSIHDVGAGGLSNA 541
Query: 534 LKELVEPE--GAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRER 591
+ ELV GAV+ ++ + ++ + +W E QE L + + + IC+RER
Sbjct: 542 MPELVNDHDMGAVLNLRQIPSLEAGMSPMAIWSNEAQERYVLAIRPESEALFDAICKRER 601
Query: 592 CPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFD 651
CP + +G T + ++D+ LD P D+ ++ +LG P+
Sbjct: 602 CPYAILGTATAIRQLQ-VDDA----LLDEQ-----------PVDMPMQVLLGGTPQMKRT 645
Query: 652 LQTEKRTKLPLSFPK---DITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVG 708
+ E++ PL F +K A+ VLR VASK +L + DR +TG+V Q Q VG
Sbjct: 646 FEREQKNLAPLDFADAGDSFDIKEAVHDVLRHPTVASKSFLISIGDRSITGMVTQDQYVG 705
Query: 709 PLHTPLADCAIIALSYYDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISEL 768
P+ADCA+ + G A S+G + L++PAA ARL++ EA+TN+ A I ++
Sbjct: 706 RYQVPVADCAVTSSGLLANTGEAMSMGERPPVALINPAASARLAVAEAITNIAGARIDKI 765
Query: 769 EDVKCSGNWMWAGKTGVEXXXXXXXXXXXXXXM-RALGVAVDGGKDSLSMCA----HVAG 823
D+ S NWM A VE + ALG+A+ GKDSLSM A V G
Sbjct: 766 SDITLSANWMAACGEDVEDAAFFDAVYAVGEELCPALGIAIPVGKDSLSMRAGWSDKVDG 825
Query: 824 EKVK----SPGTLVVSTYAPCPDITVKIEPALKEENSALVHAPVSPGKYRLGGSALAQCY 879
+ V SP +LV++ +AP D+ + P LK ++AL +S GK RLGGS LAQ
Sbjct: 826 QAVDKAVVSPMSLVITAFAPVIDVNKTLTPELKNTDAALYRLDLSQGKLRLGGSILAQTQ 885
Query: 880 KQLGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNL 939
QLG+ + F Q ++ + + HDI +GG + TV EM +NL
Sbjct: 886 SQLGNECPDLASPQDLINFFNFIQAGNQQGVISAYHDIGDGGLLATVAEMQFTNRLAINL 945
Query: 940 HVNVAANVSPIEALFNEELGIVLEVSKNDLPYV--LSEYNNNGVGAQHIGYT-----GKY 992
+++ N + + LF EELG V++V + V L+E +N IG T G
Sbjct: 946 NLS---NDNLLGQLFAEELGAVIQVLPEHIDAVMALAEEHNVSAMLSLIGQTIETPVGGA 1002
Query: 993 GMDSQVVINL--NGVNVLDTVLIDVFRMWEETSYRLECLQANTDCVLQEWKVLE--KRKG 1048
D +I G + L D+ + W + SY++ + N +CV QE+ ++ G
Sbjct: 1003 NQDKLTLITPLHQGDDALVFSRSDLQQTWTQVSYQIAKRRDNPECVQQEFDLIADPNHHG 1062
Query: 1049 ATYNVTFDPTAAV------IKTKSIKVAVLREEGINGDREMIASLMLANFDVFDVTMSDL 1102
FD V + KVA+LRE+G+NG EM A + A FD DV MSDL
Sbjct: 1063 LIAQANFDLNQKVDEPYLNSRPNKPKVAILREQGVNGQLEMAAGFVRAGFDAVDVHMSDL 1122
Query: 1103 QNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVC 1162
+I L F G+V GGFSY D LG+ GWA ILF + L QF F R DTFSLGVC
Sbjct: 1123 LEGRIDLRDFNGLVACGGFSYGDVLGAGSGWANSILFHDELRMQFVRFFTRPDTFSLGVC 1182
Query: 1163 NGCQLMAMLGWVDPDSNSKGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMG 1222
NGCQ+MA L + P G+ F +N S RFE R VKI E + + +GM
Sbjct: 1183 NGCQMMAQLKDLIP-----GAENFPRF-TYNKSARFEARTVNVKI---ERTKSILLKGMQ 1233
Query: 1223 GSVLGVWVAHGEGRFTVADGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAG 1282
S+L + VAHGEG F + S +D + +GQ+A++YVD G PTE YP+NPNGS G+ G
Sbjct: 1234 DSILPIAVAHGEG-FATLNESEIDGMANHGQIAMRYVDSQGNPTETYPLNPNGSLGGVTG 1292
Query: 1283 VRSRDGRHIAMMPHPERCVLRWQCPAPCPTVTNPSVRNSQASPWLRLFQNAYSW 1336
+ S DGR MMPHPER LR + P + W+R+F+NA +W
Sbjct: 1293 ICSTDGRVTLMMPHPER-TLRAVNHSWKPD------EWADDGAWMRMFRNARAW 1339
>UniRef50_Q7MXB0 Cluster: Phosphoribosylformylglycinamidine synthase,
putative; n=26; Bacteroidetes/Chlorobi group|Rep:
Phosphoribosylformylglycinamidine synthase, putative -
Porphyromonas gingivalis (Bacteroides gingivalis)
Length = 1234
Score = 643 bits (1589), Expect = 0.0
Identities = 438/1261 (34%), Positives = 640/1261 (50%), Gaps = 97/1261 (7%)
Query: 90 IGPRFNFSTADSSNSVQICESVGLRDVVRLEVSTRYLITFGKQKNVTEKHFENLAAVLHD 149
+GPR T S+N+V+I +++ + + R+E F K + F+ + L++
Sbjct: 49 VGPRREMVTPWSTNAVEITQNMNVAGIRRIE-------EFFPVKGA-DAEFDPMLQALYE 100
Query: 150 RMTQCVYTKDNLPRKSFNEGLPKDLEPWFVVPLQEQGISAMRKVNDKLGLAFDTWDMEFY 209
++ Q ++ D P EP ++ +++ +R N+ GLA ++ Y
Sbjct: 101 QLDQKIFDIDRKP------------EP--IISVKD-----IRAYNEAEGLALSEDEIS-Y 140
Query: 210 MDLFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLIDMVASTQKTSN 269
+ ++ R T ELF +Q NSEH RH F G ++DG+E SL +++ T +
Sbjct: 141 LKGVSERIGRPLTDSELFGFSQVNSEHCRHKIFGGTFIIDGEEKESSLFNLIKRTSAVNP 200
Query: 270 NNNVIKFGDNSSAIKGFQHTILRPTNVRGPSQVIQKKTESDIIFTAETHNMPTAVAPFSG 329
N V + DN + I+G + P + P K ++ + AETHN PT V PF+G
Sbjct: 201 NLLVSAYKDNVAFIQGPKVEQFAPRSADKPDYFETKTIDTVLSLKAETHNFPTTVEPFNG 260
Query: 330 ATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQII 389
A TGTGG IRD G+ +AGTA Y G P+E+K E + +P QI+
Sbjct: 261 AATGTGGEIRDRMAGGKSSIPLAGTAVYMTSYARTDG-TRPFEKKLSERRWLYQSPRQIL 319
Query: 390 IEASNGASDYGNKFGEPVISGFVQSYGLKNA-DNTREEFVKPIMFSGGIGYMPHSMIKKN 448
+ASNGASD+GNKFG+P+I+G V ++ + D T + K IM +GG+GY S K
Sbjct: 320 TKASNGASDFGNKFGQPLITGSVLTFEHQETPDTTCYGYDKVIMLAGGVGYAKQSDALKG 379
Query: 449 KPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVV 508
+P G +V +++ A+QR + EM R+ V+
Sbjct: 380 EPSPGEKVVILGGDNYRIGMGGGAVSSVNTGQLSG---SIELNAIQRSNPEMQKRVQNVI 436
Query: 509 RGCLESDVNPVESIHDQGAGGNGNVLKELVEPEGAVVFTKEFQLGDPTITTLELWGAEYQ 568
R E+D NP+ SIHD GAGG+ N L ELVE G + +GDPT++ E+ G E Q
Sbjct: 437 RAIAENDNNPIVSIHDHGAGGHLNCLSELVEATGGRIDMDRLPVGDPTLSAKEIIGNESQ 496
Query: 569 ENDALLCSKANRHILEEICRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLES 628
E +L + + + +I RER P+ VGE T D +F+ R +
Sbjct: 497 ERMGMLMQEKDLEYVRKIAERERAPMYVVGETTDD-----------MRFVFRKDN----- 540
Query: 629 KSKLPYDLHLEAVLGNMPRKTFDLQT-EKRTKLPLSFPKDITVKSALDRVLRLVNVASKR 687
+ P D+ L+ + G PR + +T E R + P P + L++VLR+ +VA K
Sbjct: 541 -GECPIDMKLDDMFGKPPRTIMEDRTIEHRYQAPQYDPARLD--EYLEQVLRMESVACKD 597
Query: 688 YLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALSYYDLVGSATSIGTQNIKGLLDPAA 747
+LTNKVDR VTG VA+QQC G L PL+D +AL Y G ATSIG L DPAA
Sbjct: 598 WLTNKVDRSVTGRVARQQCQGELQLPLSDLGAMALDYRGHSGVATSIGHAPQAALADPAA 657
Query: 748 GARLSLGEALTNLVFAGISE-LEDVKCSGNWMWAGKTGVEXXXXXXXXXXXXXXMRALGV 806
G+ L++ EALTN+VFA + +E V S NWMW + E LG+
Sbjct: 658 GSVLAIAEALTNIVFAPLRNGIEGVSLSANWMWPCRNEGEDARLYRAVEACSDFAVDLGI 717
Query: 807 AVDGGKDSLSMCAHVAGEKVKSPGTLVVSTYAPCPDITVKIEPALKE-ENSALVHAPVSP 865
+ GKDSLSM +KV SPGT+++S A DI + P L +AL + S
Sbjct: 718 NIPTGKDSLSMTQKYEDKKVLSPGTVIISAAAEVTDIRRIVSPVLSHIAATALYYIDFSF 777
Query: 866 GKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITT 925
+ LGGSA AQ +GD + F Q+L+ + +++GHDIS GG IT
Sbjct: 778 CPFSLGGSAFAQSLGTIGDEVPTVRDPEYFRDAFNTVQELIDKGLVLAGHDISAGGLITA 837
Query: 926 VLEMGIGGV-RGLNLHVNVAANVSPIEALFNEELGIVLEVSKNDLPYVLSEYNNNGVGAQ 984
+LEM V GL + ++ I+ LF E GI+++V D V + G+G
Sbjct: 838 LLEMCFANVVGGLEVELDNLVEDDLIKVLFAENPGILIQVK--DRKAVDKILTDAGIGFL 895
Query: 985 HIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFR-MWEETSYRLECLQANTDCVLQEWKVL 1043
I K + ++I+ +G L ID R +W E+SY L+C Q+ ++
Sbjct: 896 PIA---KPTQERHLLIHKDGAEYLFG--IDHMRDVWYESSYLLDCFQSGNTLAGNRFENY 950
Query: 1044 EKRKGATY---NVTFDPTAAVI----KTKS-IKVAVLREEGINGDREMIASLMLANFDVF 1095
+++ + T D A + KT S I+ A++R++G NG+REM +L LA FDV
Sbjct: 951 KEQPVVYHFPKQFTGDLKAMGLDPDRKTASGIRAAIIRDKGTNGEREMAYALYLAGFDVK 1010
Query: 1096 DVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKDRKD 1155
DV ++DL + + TL+ + +VF GGFS +D LGSAKGWA GILF+E + F R D
Sbjct: 1011 DVHLTDLTSGRETLEDIRMIVFCGGFSNSDVLGSAKGWAGGILFNEQAKATLDRFFARPD 1070
Query: 1156 TFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQIFLDHNSSERFECRWSAVKIHENENKED 1215
T SLG+CNGCQLMA L + P+ K L HN S++FE + ++I N++
Sbjct: 1071 TLSLGICNGCQLMAELELLYPEHELKHK------LVHNESQKFESTFVTLEIPHNDS--- 1121
Query: 1216 VWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNG 1275
+ + GS +GVW AHGEGRF++ +K Y V +Y + DG YP NPNG
Sbjct: 1122 IMLGNLAGSKIGVWCAHGEGRFSL---PYEEKAY---HVVAKY-EYDG-----YPANPNG 1169
Query: 1276 SPDGLAGVRSRDGRHIAMMPHPERCVLRWQCPAPCPTVTNPSVRNSQASPWLRLFQNAYS 1335
SP +AG+ S DGRH+ MMPHPER + WQ C Q +PW++ F+NAY
Sbjct: 1170 SPHRIAGLCSADGRHLTMMPHPERSIFPWQ----CGYYPESQRHEHQVTPWMQAFRNAYE 1225
Query: 1336 W 1336
W
Sbjct: 1226 W 1226
>UniRef50_P38972 Cluster: Phosphoribosylformylglycinamidine synthase;
n=19; cellular organisms|Rep:
Phosphoribosylformylglycinamidine synthase -
Saccharomyces cerevisiae (Baker's yeast)
Length = 1358
Score = 636 bits (1570), Expect = e-180
Identities = 427/1303 (32%), Positives = 648/1303 (49%), Gaps = 67/1303 (5%)
Query: 71 AVRNETIFKSNDNSQLLIEIGPRFNFSTADSSNSVQICESVGLRDVV-RLEVSTRYLITF 129
AV N + LI + PR + SS + I GL+D V R+E LI
Sbjct: 84 AVANNLPSSALGEDTYLIRVVPRSGTISPWSSKATNIAHVCGLQDKVQRIERGLALLIKT 143
Query: 130 GKQKNVTEKHFENLAAVLHDRMTQCVY-TKDNLPRKSFNEGLPKDLEPWFVVP--LQEQG 186
+ E + ++DRMTQ +Y T+ F PK L + P ++
Sbjct: 144 VPGFPLLENLNDISLKCVYDRMTQQLYLTEPPNTMSIFTHEEPKPLVHVPLTPKDTKQSP 203
Query: 187 ISAMRKVNDKLGLAFDTWDMEFYMDLFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKL 246
+ K N +LGLA D+ +ME+ + FV +KRDPT VELF AQ NSEH RH F
Sbjct: 204 KDILSKANTELGLALDSGEMEYLIHAFVETMKRDPTDVELFMFAQVNSEHCRHKIFNADW 263
Query: 247 VLDGKEINESLIDMVASTQKTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRGPSQVIQKK 306
+DG + +L M+ +T K + + + DN++ + N + K
Sbjct: 264 TIDGIKQQFTLFQMIRNTHKLNPEYTISAYSDNAAVLDSENDAFFFAPNST-TKEWTSTK 322
Query: 307 TESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPG 366
++ ETHN PTAV+PF GA TG+GG IRD GRG T G +G+SV +L IPG
Sbjct: 323 ERIPLLIKVETHNHPTAVSPFPGAATGSGGEIRDEGATGRGSKTKCGLSGFSVSDLLIPG 382
Query: 367 YDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTREE 426
+ PWE + P + A+ L I+IEA G++ + N+FG P I+G+ ++ K ++ +E
Sbjct: 383 NEQPWELNIGK-PYHIASALDIMIEAPLGSAAFNNEFGRPCINGYFRTLTTKVLNHQGKE 441
Query: 427 ----FVKPIMFSGGIGYMPHSMIKKNKP-DKGMLLVKXXXXXXXXXXXXXXXXXXXXXXX 481
F KPIM +GG G + KN P G L+
Sbjct: 442 EIRGFHKPIMIAGGFGTVRPQFALKNTPITPGSCLIVLGGQSMLIGLGGGAASSVASGEG 501
Query: 482 DARDHALDFGAVQRGDAEMGNRLNRVVRGCLE-SDVNPVESIHDQGAGGNGNVLKELVEP 540
A LDF +VQRG+ EM R +V+ C+ + NP++SIHD GAGG N L ELV
Sbjct: 502 SAD---LDFASVQRGNPEMERRCQQVIDACVALGNNNPIQSIHDVGAGGLSNALPELVHD 558
Query: 541 E--GAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVG 598
GA ++ +P ++ +E+W E QE L S + I EEIC+RER P + VG
Sbjct: 559 NDLGAKFDIRKVLSLEPGMSPMEIWCNESQERYVLGVSPQDLSIFEEICKRERAPFAVVG 618
Query: 599 EVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKRT 658
T + + ++ED + P DL + + G P+ + + TE
Sbjct: 619 HATAEQKL-IVEDPLLKT---------------TPIDLEMPILFGKPPKMSRETITEALN 662
Query: 659 KLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCA 718
+ + +++ A+ RVL L +V SK +L DR VTGL+ + Q VGP P+AD
Sbjct: 663 LPEANLSEIPSLQDAIQRVLNLPSVGSKSFLITIGDRSVTGLIDRDQFVGPWQVPVADVG 722
Query: 719 IIALSYYDLV---GSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSG 775
+ S + + G A ++G + + L+ +A A+LS+ E+L N+ A + L +K S
Sbjct: 723 VTGTSLGETIISTGEAMAMGEKPVNALISASASAKLSVAESLLNIFAADVKSLNHIKLSA 782
Query: 776 NWMW-AGKTGVEXXXXXXXXXXXXXXMRALGVAVDGGKDSLSMCAHVAGEKVKSPGTLVV 834
NWM A G ALGVA+ GKDS+SM ++V +P +L +
Sbjct: 783 NWMSPASHQGEGSKLYEAVQALGLDLCPALGVAIPVGKDSMSMKMKWDDKEVTAPLSLNI 842
Query: 835 STYAPCPDITVKIEPALKE--ENSALVHAPVSPGKYR--LGGSALAQCYKQLGDNXXXXX 890
+ +AP + + P L ++S LV +S + LG SAL Q Y Q+G+
Sbjct: 843 TAFAPVFNTSKTWTPLLNRNTDDSVLVLVDLSAKQETKSLGASALLQVYNQVGNKSPTVY 902
Query: 891 XXXXXKSLFKITQKLLKEKK--LISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVS 948
K + +L ++K+ +++ HD S+GG + T+LEM GL ++++ S
Sbjct: 903 DNAILKGFLESLIQLHQQKEDIVLAYHDRSDGGLLITLLEMAFASRCGLEINIDGGDLES 962
Query: 949 PIEALFNEELGIVLEVSKNDLPYVLSEYNNNGVGAQHIGYTGKYGMDSQVVINLNGVN-- 1006
+ LFNEELG V ++S +L N NGV ++I GK SQ + +N
Sbjct: 963 QLTNLFNEELGAVFQISAKNLSKFEKILNENGVAKEYISIVGKPSFQSQEIKIINSTTND 1022
Query: 1007 -VLDTVLIDVFRMWEETSYRLECLQANTDCVLQEWKVL--EKRKGATYNVTFDPTAAV-- 1061
+ ++ + W +TSY ++ L+ N +E+ + ++ G Y +T++P +
Sbjct: 1023 VIYANSRSELEQTWSKTSYEMQKLRDNPKTAEEEFASITDDRDPGLQYALTYNPADDMKI 1082
Query: 1062 ---IKTKSIKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFP 1118
+ ++ KVA+LRE+G+NG EM A F+ DVTM+DL + LD F G+
Sbjct: 1083 GLELSSQRPKVAILREQGVNGQMEMAWCFQQAGFNSVDVTMTDLLEGRFHLDDFIGLAAC 1142
Query: 1119 GGFSYADTLGSAKGWAAGILFSESLSSQFA-HFKDRKDTFSLGVCNGCQLMAMLGWVDPD 1177
GGFSY D LG+ GWA +L+ E + SQF+ F +R+DTF+ G CNGCQ ++ L + P
Sbjct: 1143 GGFSYGDVLGAGAGWAKSVLYHEGVRSQFSKFFNERQDTFAFGACNGCQFLSRLKDIIPG 1202
Query: 1178 SNSKGSNKAQIFLDHNSSERFECRWSAVKI---HENENKEDVWFRGMGGSVLGVWVAHGE 1234
+ S + N SE++E R V+I +N ++E V+ GM GS L + VAHGE
Sbjct: 1203 CENWPS------FERNVSEQYEARVCMVQISQEKDNSSEESVFLNGMAGSKLPIAVAHGE 1256
Query: 1235 GRFTVA-DGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAM 1293
G+ T + L+K K+G ++YVD+ G TE +P NPNGS +G+AG++S +GR +AM
Sbjct: 1257 GKATFSKSAEQLEKFEKDGLCCIRYVDNYGNVTERFPFNPNGSTNGIAGIKSPNGRVLAM 1316
Query: 1294 MPHPERCVLRWQCPAPCPTVTNPSVRNSQASPWLRLFQNAYSW 1336
MPHPER V R + + P PW+RLF++A W
Sbjct: 1317 MPHPER-VCRLEANSWYP--EGKYEEWGGYGPWIRLFRSARRW 1356
>UniRef50_Q9JXK5 Cluster: Phosphoribosylformylglycinamidine synthase;
n=12; Betaproteobacteria|Rep:
Phosphoribosylformylglycinamidine synthase - Neisseria
meningitidis serogroup B
Length = 1320
Score = 634 bits (1567), Expect = e-180
Identities = 428/1332 (32%), Positives = 665/1332 (49%), Gaps = 98/1332 (7%)
Query: 11 AFSLHKTNEILQKLKFVDSDIKDLSTELCYHVELAEGCEYLNINQIKVLKWLLSSPLQPQ 70
A S + ++LQK + LS+E Y V + + + +++ L L Q
Sbjct: 12 ALSDFRVEKLLQKAAALGLPEVKLSSEFWYFVGSEKALDAATVEKLQAL-------LAAQ 64
Query: 71 AVRNETIFKSNDNSQLLIEIGPRFNFSTADSSNSVQICESVGLRDVVRLEVSTRYLITFG 130
+V E K+ + L + + PR + +S + I E+ GL + R+E +
Sbjct: 65 SV--EQTPKAREGLHLFL-VTPRLGTISPWASKATNIAENCGLAGIERIERGMAVWL--- 118
Query: 131 KQKNVTEKHFENLAAVLHDRMTQCVYTKDNLPRKSFNEGLPKDLEPWFVVPLQEQGISAM 190
+ + ++ + AA+LHDRMT+ V K F+ + E + V + G A+
Sbjct: 119 -EGRLNDEQKQQWAALLHDRMTESVLPDFQTASKLFHH---LESETFSGVDVLGGGKEAL 174
Query: 191 RKVNDKLGLAFDTWDMEFYMDLFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDG 250
K N ++GLA ++++ ++ + L+R+P+ VEL AQ+NSEH RH F +L+G
Sbjct: 175 VKANTEMGLALSADEIDYLVENY-QALQRNPSDVELMMFAQANSEHCRHKIFNADFILNG 233
Query: 251 KEINESLIDMVASTQKTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRGPSQVIQKKTESD 310
++ +SL M+ T V+ + DNSS I+G + P ++ ++
Sbjct: 234 EKQPKSLFGMIRDTHNAHPEGTVVAYKDNSSVIEGAKIERFYPNAAENQGYRFHEE-DTH 292
Query: 311 IIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLP 370
II ETHN PTA+APF+GA TG GG IRD G+G AG G++V NL+IP P
Sbjct: 293 IIMKVETHNHPTAIAPFAGAATGAGGEIRDEGATGKGSRPKAGLTGFTVSNLNIPDLKQP 352
Query: 371 WEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKP 430
WE+ + P + ++PL I+IE G + + N+FG P + G+ +++ K D + KP
Sbjct: 353 WEQ-DYGKPEHISSPLDIMIEGPIGGAAFNNEFGRPNLLGYFRTFEEK-FDGQVRGYHKP 410
Query: 431 IMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDF 490
IM +GG+G + K++ +G LL++ DA +LDF
Sbjct: 411 IMIAGGLGSIQAQQTHKDEIPEGALLIQLGGPGMLIGLGGGAASSMDTGTNDA---SLDF 467
Query: 491 GAVQRGDAEMGNRLNRVVRGCLE-SDVNPVESIHDQGAGGNGNVLKELVEP--EGAVVFT 547
+VQRG+ E+ R V+ C + NP+ SIHD GAGG N ELV GAV
Sbjct: 468 NSVQRGNPEIERRAQEVIDRCWQLGGKNPIISIHDVGAGGLSNAFPELVNDARRGAVFKL 527
Query: 548 KEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGEVTGDGYMS 607
+E L + + L++W E QE L + + IC RERCP + VG T DG++
Sbjct: 528 REVPLEEHGLNPLQIWCNESQERYVLSILEKDLDAFRAICERERCPFAVVGTATDDGHLK 587
Query: 608 LIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKRTKLPLSFPKD 667
+ +D + P DL L +LG +P+ T +T +K P D
Sbjct: 588 VRDDLFANN----------------PVDLPLNVLLGKLPKTTRTDKTVAPSKKPF-HAGD 630
Query: 668 ITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALSYYDL 727
I + A RVLRL VA+K +L DR V GL + Q VG TP+ADCA+ + +
Sbjct: 631 IDITEAAYRVLRLPAVAAKNFLITIGDRSVGGLTHRDQMVGKYQTPVADCAVTMMGFNTY 690
Query: 728 VGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEX 787
G A S+G + L D A R+ +GEA+TN+ I ++ ++K S NWM A E
Sbjct: 691 RGEAMSMGEKPTVALFDAPASGRMCVGEAITNIAAVNIGDIGNIKLSANWMAACGNEGED 750
Query: 788 XXXXXXXXXXXXXMRALGVAVDGGKDSLSM-CAHVAGEKVK---SPGTLVVSTYAPCPDI 843
+AL +++ GKDSLSM GE+ K SP +L++S +AP D+
Sbjct: 751 EKLYRTVEAVSKACQALDLSIPVGKDSLSMKTVWQDGEEKKSVVSPLSLIISAFAPVKDV 810
Query: 844 TVKIEPALKE-ENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKIT 902
+ P LK E+S L+ + GK R+GGSA Q Y + + K+ + +
Sbjct: 811 RKTVTPELKNVEDSVLLFVDLGFGKARMGGSAFGQVYNNMSGDAPDLDDTGRLKAFYSVI 870
Query: 903 QKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNV---------------AANV 947
Q+L+ E KL++ HD S+GG ++EM G GL++ +N+ +
Sbjct: 871 QQLVAENKLLAYHDRSDGGLFAVLVEMAFAGRCGLDIDLNLLLAQTFITNHTALSQSLRT 930
Query: 948 SPIEAL-----------FNEELGIVLEVSKNDLPYVLSEYNNNGVGAQHIGYTGKYGMDS 996
++AL FNEELG V++V K D+ +++ + + ++ G ++
Sbjct: 931 EEVKALAEWQETIARTLFNEELGAVIQVRKQDVADIINLFYQQQL-HHNVFEIGTLTDEN 989
Query: 997 QVVINLNGVNVLDTVLIDVFRMWEETSYRLECLQANTDCVLQEWKVL-EKRKGA-----T 1050
++I +++ LI + + W+ETS++++ L+ N C E+ ++ + + A
Sbjct: 990 TLIIRDGQTHLISDNLIKLQQTWQETSHQIQRLRDNPACADSEFALIGDNERSALFADVK 1049
Query: 1051 YNVTFDPTAAVIKT-KSIKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITL 1109
++V D A I + K+A+LRE+G+NG EM A+ A FD +DV MSDL +I L
Sbjct: 1050 FDVNEDIAAPFINSGAKPKIAILREQGVNGQIEMAAAFTRAGFDAYDVHMSDLMAGRIHL 1109
Query: 1110 DAFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMA 1169
F+ + GGFSY D LG+ +GWA ILF +L QFA F DT +LGVCNGCQ+++
Sbjct: 1110 ADFKMLAACGGFSYGDVLGAGEGWAKSILFHPALRDQFAAFFADPDTLTLGVCNGCQMVS 1169
Query: 1170 MLGWVDPDSNSKGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVW 1229
L + P + G K N SE+FE R S V + ++ + + M GS L V
Sbjct: 1170 NLAEIIP--GTAGWPK----FKRNLSEQFEARLSMVHVPKSAS---LILNEMQGSSLPVV 1220
Query: 1230 VAHGEGR--FTVADGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRD 1287
V+HGEGR F + G++ L +A+QY+D + T+ YP+NPNGSP G+AGV + D
Sbjct: 1221 VSHGEGRADFALHGGNISADL----GIALQYIDGQNQVTQTYPLNPNGSPQGIAGVTNAD 1276
Query: 1288 GRHIAMMPHPER 1299
GR MMPHPER
Sbjct: 1277 GRITIMMPHPER 1288
>UniRef50_Q2UAH0 Cluster: Phosphoribosylformylglycinamidine synthase;
n=15; Pezizomycotina|Rep:
Phosphoribosylformylglycinamidine synthase - Aspergillus
oryzae
Length = 1364
Score = 592 bits (1462), Expect = e-167
Identities = 432/1319 (32%), Positives = 644/1319 (48%), Gaps = 90/1319 (6%)
Query: 78 FKSNDNSQLLIEIGPRFNFSTADSSNSVQICESVGLRDVV-RLEVSTRYLITFGKQKNVT 136
F + D + + PR + SS + I GLR V R+E + I+ + +
Sbjct: 74 FSAEDGQFDVFYVFPRTGTISPWSSQATGIAHVCGLRKYVDRIERGLK--ISCLRASSAE 131
Query: 137 EKHFENLAAVLHDRMTQCVYTKDNLPRKSFNEGLPKDLEPWFVVPLQEQGISAMRKVNDK 196
K VLHDRMTQ + ++ F+E P LE + + +++ N +
Sbjct: 132 YK--SGFQDVLHDRMTQVLGQEEPDLHLMFSEHSPLPLETIPLHGSDKSPKEVLQEANKR 189
Query: 197 LGLAFDTWDMEFYMDLFV--NKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEIN 254
LGLA + ++E+ + + + RDPT VELF AQ NSEH RH F V+DGK++
Sbjct: 190 LGLALEESEIEYIAEAYGPNGPIARDPTDVELFMFAQVNSEHCRHKQFNASWVIDGKQMP 249
Query: 255 ESLIDMVASTQKTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRGPSQVIQKKTESDIIFT 314
SL M+ +T K + V + DN++ ++G P G K +
Sbjct: 250 NSLFAMIRNTHKKNPEYTVSAYSDNAAVLEGDVAAHWAPDATTGEWN--HTKEIVHFLAK 307
Query: 315 AETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEK 374
ETHN PTAV+P+ GA TG+GG IRD VGRG AG AGY V +L IPG PWE
Sbjct: 308 VETHNHPTAVSPYPGAATGSGGEIRDEGAVGRGSKPKAGLAGYCVSDLQIPGLKQPWELD 367
Query: 375 GWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSY----GLKNADNTREEFVKP 430
+ P++ A+ L I++EA G++ + N+FG P ISG+ ++ + N + KP
Sbjct: 368 VGK-PNHIASSLDIMLEAPIGSAAFNNEFGRPCISGYFRTLLTEIDIGNGQKEVRGYHKP 426
Query: 431 IMFSGGIGYM-PHSMIKKNKPDK-GMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHAL 488
IM +GG+G + P IKK + K G LV A L
Sbjct: 427 IMLAGGVGTVRPQHAIKKPEVVKPGAFLVVLGGPAMLIGLGGGAASSITSGEGSAE---L 483
Query: 489 DFGAVQRGDAEMGNRLNRVVRGCLE-SDVNPVESIHDQGAGGNGNVLKELVEPEG--AVV 545
DF +VQRG+AE+ R V+ C D NP++ IHD GAGG N L EL+ G A
Sbjct: 484 DFASVQRGNAEVQRRAQEVINACTAMGDNNPIKFIHDVGAGGLSNALPELIHDSGLGATF 543
Query: 546 FTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGEVTGDGY 605
+E D +++ +++W E QE + + + + I RERC S VG G G
Sbjct: 544 ELREIDSADKSMSPMQIWCCEAQERYVMAVGEDSMNKFTAIANRERCGFSVVGR--GGG- 600
Query: 606 MSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKR-------- 657
S EK L +R E P DL L + G P+ T +++ K
Sbjct: 601 -----TSEEEKRLVLMDRDSTEYPK--PIDLPLSVLFGKPPKMTRVVESRKLKLPAVDAT 653
Query: 658 -TK-LPLSFPKDIT-VKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPL 714
TK LP P + + A +RVL L VASK +L DR V GL A+ Q VG TP+
Sbjct: 654 LTKYLPALAPNHLELIGEAANRVLSLPAVASKSFLITIGDRTVGGLTARDQMVGRWQTPV 713
Query: 715 ADCAIIALSYYDLV--GSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAG-ISELEDV 771
+D A+ A + V G A ++G + L+ PAA AR+++ E+L N+ A + L V
Sbjct: 714 SDVAVTATALLQGVKTGEAMAMGERPSLALISPAASARMAVAESLMNIAAADLVDRLSHV 773
Query: 772 KCSGNWMWAGKTGVEXXXXXXXXXXXXXXM-RALGVAVDGGKDSLSMC------AHVAGE 824
K S NWM A E + LG+++ GKDS+SM A +
Sbjct: 774 KLSANWMSASSHPGEGAAIYEAAEAIGMDLCPKLGISIPVGKDSMSMKMKWTDEASKQAK 833
Query: 825 KVKSPGTLVVSTYAPCPDITVKIEPALKE----ENSALVHAPVSPGKYRLGGSALAQCYK 880
+V +P +LV+S +AP + PAL+ + L+ +S G+ LGGSALAQ +
Sbjct: 834 EVTAPMSLVISAFAPVGNYRKTWTPALRRLEDVGETVLMFVDLSFGRKTLGGSALAQVFN 893
Query: 881 QLGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLH 940
Q+GD+ K F TQ+L +++ HD S+GG TT+ EM G G+ +
Sbjct: 894 QVGDDCPDVRDVEIFKDFFDATQQLQDAGIVLAYHDRSDGGLFTTLAEMMFAGRCGVEVM 953
Query: 941 V-NVAANVSP---IEALFNEELGIVLEVSKNDLPYVLSEYNNNGVGAQHIGYTGKYGMDS 996
+ N+ + +E LF EELG V +V K S + G A I G+ +
Sbjct: 954 LDNICPSSGTKDVVETLFTEELGAVFQVRKEHEIQFRSCFATCGPPAGLIHKIGRVSERT 1013
Query: 997 Q--VVINLNGVNVLDTVLIDVFRMWEETSYRLECLQANTDCVLQEW-KVLEKRK-GATYN 1052
+ + I V ++ + W TSY ++ ++ N C QE+ +L+ G ++N
Sbjct: 1014 KQNLAIYHGHTLVYRNNRANLQQTWSSTSYHMQKMRDNAACADQEYANILDDADPGLSWN 1073
Query: 1053 VTFDPTAAVIK-----------TKSIKVAVLREEGINGDREMIASLMLANFDVFDVTMSD 1101
TFDP + + +VA+LRE+G+N EM + +A F DV M+D
Sbjct: 1074 PTFDPKDKALPMLTSLTSMSPFSNKPRVAILREQGVNSQAEMAFAFNMAGFSAVDVHMTD 1133
Query: 1102 LQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGV 1161
+ + +++L +F G+ GGFSY D LG+ +GWA +L E+ S+F F +R DTF+LGV
Sbjct: 1134 IISGRVSLASFVGMAACGGFSYGDVLGAGQGWAKSVLLHENTRSEFQSFFERPDTFALGV 1193
Query: 1162 CNGCQLMAMLGWVDPDSNSKGSNKAQIFLDHNSSERFECRWSAVKIHE-NENKEDVWFRG 1220
CNGCQ ++ L + P + + S + N+SE++E R V++ + + ++ V+F G
Sbjct: 1194 CNGCQFLSRLKELIPGAQNWPS------FERNASEQYEGRVCMVRVSDPDPSRPSVFFHG 1247
Query: 1221 MGGSVLGVWVAHGEGR--FTVADGSLLDKLYKNGQVAVQYVDDDG-KPTEVYPMNPNGSP 1277
M G+ L + VAHGEGR F+ + + G VQYVD+ G KPT YP NPNGSP
Sbjct: 1248 MDGTSLPIAVAHGEGRASFSPSSNVTAQSFVQEGLAPVQYVDNAGLKPTMKYPFNPNGSP 1307
Query: 1278 DGLAGVRSRDGRHIAMMPHPERCVLRWQCPAPCPTVTNPSVRNSQASPWLRLFQNAYSW 1336
+G+AG+R+ +GR +A+MPHPER V+ + + PW R+F +A W
Sbjct: 1308 EGIAGIRNANGRVLAIMPHPERTVM----GGIASWLPAKAQEWGDIGPWGRVFYSARRW 1362
>UniRef50_Q8XYN6 Cluster: Phosphoribosylformylglycinamidine synthase;
n=49; cellular organisms|Rep:
Phosphoribosylformylglycinamidine synthase - Ralstonia
solanacearum (Pseudomonas solanacearum)
Length = 1369
Score = 576 bits (1421), Expect = e-162
Identities = 426/1321 (32%), Positives = 639/1321 (48%), Gaps = 115/1321 (8%)
Query: 92 PRFNFSTADSSNSVQICESVGLRDVVRLEVSTRYLITF---------GKQKNVTEKHFEN 142
PRF + +S + +I L + R+E + +T G +K + E
Sbjct: 80 PRFGTISPWASKATEIARHCALPQIHRIERGVEFTVTCKKGLLRGLTGGRKQLDEATRAA 139
Query: 143 LAAVLHDRMTQCVYTKDNLPRKSFNEGLPKDLEPWFVVPLQEQ--GISAMRKVNDKLGLA 200
+AA LHDRMT+ V F+ LP + + + G A+ N ++GLA
Sbjct: 140 VAAHLHDRMTEIVVATREAGYGLFDV-LPAKALRFVDLGSGDAAAGRGALEAANTEMGLA 198
Query: 201 FDTWDMEFYMDLFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLIDM 260
++++ +D + KL R+PT VEL AQ+NSEH RH F +DG+ ++SL M
Sbjct: 199 LSDDEIDYLVDAY-RKLGRNPTDVELMMFAQANSEHCRHKIFNADWTIDGETQDKSLFAM 257
Query: 261 VASTQKTSNNNNVIKFGDNSSAIKGFQHTILRP----TNVRGPSQVIQKKTESDIIFTAE 316
+ +T + + V+ + DN++ ++G P G Q +++ + + E
Sbjct: 258 IRNTHQLAPQGTVVAYSDNAAVMEGGMAERWFPHAGTDGETGVPQYGRREALTHTLMKVE 317
Query: 317 THNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGW 376
THN PTA++PF GA+TG GG IRD GRG AG G++V NL +P WE
Sbjct: 318 THNHPTAISPFPGASTGAGGEIRDEGATGRGAKPKAGLTGFTVSNLLLPEAVQSWENARD 377
Query: 377 EY------------------PSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLK 418
P A+PLQI+IE G + + N+FG P + G+ + Y +
Sbjct: 378 TAQPAAQRNPGDTAPGPVGKPDRIASPLQIMIEGPIGGAAFNNEFGRPNLGGYFRVYE-Q 436
Query: 419 NADNTREEFVKPIMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXX 478
N T + KPIM +GGIG + K+ G LLV+
Sbjct: 437 NVGGTVRGYHKPIMIAGGIGNIDAGHTHKHGLPAGTLLVQLGGPGMRIGMGGGAASSMAT 496
Query: 479 XXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLE-SDVNPVESIHDQGAGGNGNVLKEL 537
A LDF +VQRG+ EM R V+ C + NP+ SIHD GAGG N EL
Sbjct: 497 GTNTAD---LDFDSVQRGNPEMQRRAQEVINACWALGEDNPILSIHDVGAGGISNAFPEL 553
Query: 538 VE--PEGAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVS 595
V+ GA ++ L + ++ E+W E QE L + + + +C RER P S
Sbjct: 554 VDGADRGARFDLRQVHLEESGLSPAEIWCNESQERYTLAIAPGDFPRFQAMCERERAPFS 613
Query: 596 FVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTE 655
VG T + + +++ ++ P ++ ++ +LG PR D++
Sbjct: 614 VVGFATEEQQLQVVDGD-----------APADAVEHFPVNMPMDVLLGKPPRMHRDVRRV 662
Query: 656 KRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLA 715
+ LP + +++ VLR VASK +L DR V GL + Q VGP P+A
Sbjct: 663 AQA-LPEVDVTGLDLETVARDVLRHPTVASKSFLITIGDRTVGGLNTRDQMVGPWQVPVA 721
Query: 716 DCAIIALSYYDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSG 775
D A+ L Y G A ++G + ++D A R+++GEA+TN+ A I+ L +K S
Sbjct: 722 DVAVTTLDYKGYAGEAMTMGERTPLAVIDAPASGRMAIGEAITNIAAAPIASLAQLKLSA 781
Query: 776 NWMWA-GKTGVEXXXXXXXXXXXXXXMRALGVAVDGGKDSLSMCA--HVAGE--KVKSPG 830
NWM A G G + ALG+++ GKDSLSM AGE +V +P
Sbjct: 782 NWMAACGVDGEDARLYDTVKAVGMELCPALGISIPVGKDSLSMRTKWDDAGEAKEVVAPV 841
Query: 831 TLVVSTYAPCPDITVKIEPALKEENSA-------LVHAPVSPGKYRLGGSALAQCYKQLG 883
+L+VS +AP D+ + P LK SA L+ + GK+RLGGS LAQ +Q+G
Sbjct: 842 SLIVSAFAPVTDVRKTLTPQLKPVASAGEAADTTLIVIDLGHGKHRLGGSILAQVTQQIG 901
Query: 884 DNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHV-- 941
++ K F Q+L L++ HD S+GG TV EM G G++++V
Sbjct: 902 NSVPDVGDAEDLKRFFAAIQQLNAAGMLLAYHDRSDGGLWATVCEMAFAGHCGVSINVDM 961
Query: 942 ---------------NVAANVS------PIEALFNEELGIVLEVSKNDLPYVLSEYNNNG 980
N A VS + ALF EELG V++V V + +G
Sbjct: 962 LTLDGAHASDYGDAKNWAQQVSGRRADMTLRALFAEELGAVIQVPAAQRDAVFAVLREHG 1021
Query: 981 VGA-QHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFRMWEETSYRLECLQANTDCVLQE 1039
+ A H+ G Q+ I + V I++ R W + S+R+ L+ N +C E
Sbjct: 1022 LAACSHV--IGAPNASGQIEIWRDAKKVFSAPRIELQRAWTDVSWRIASLRDNPECTQSE 1079
Query: 1040 W-KVLE-KRKGATYNVTF----DPTAAVIKTKS-IKVAVLREEGINGDREMIASLMLANF 1092
+ ++L+ + G + N+TF D A I T + ++A+LRE+G+N EM ++ A F
Sbjct: 1080 YDRLLDAEDPGISPNLTFDLAEDVAAPFIATGARPRMAILREQGVNSQVEMAYAMDKAGF 1139
Query: 1093 DVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKD 1152
D +DV MSDL + L F+G V GGFSY D LG+ +GWA ILF+ L+ QFA F +
Sbjct: 1140 DAYDVHMSDLLAGRTRLADFKGFVACGGFSYGDVLGAGEGWAKTILFNGMLAEQFAAFFN 1199
Query: 1153 RKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQIFLDHNSSERFECRWSAVKIHENEN 1212
R D+ +LGVCNGCQ+MA L + P + A N SE++E R V++ E
Sbjct: 1200 RADSIALGVCNGCQMMANLAPIIPGAG------AWPKFTRNQSEQYEGRLVTVQV---EA 1250
Query: 1213 KEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMN 1272
+++ GM GS + + VAHGEG AD S + K V ++YVD+ G+ T+ YP+N
Sbjct: 1251 SPSIFYAGMEGSRIPIVVAHGEG---YADFSQQGDIGKVA-VGLRYVDNRGEVTQTYPLN 1306
Query: 1273 PNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCPAPCPTVTNPSVRNSQASPWLRLFQN 1332
PNGSP G+A V + DGR +MPHPER V R + P + + +SPW+R+F+N
Sbjct: 1307 PNGSPQGIASVTTHDGRFTVLMPHPER-VFRAVQMSWHP--KDWAAAGDGSSPWMRMFRN 1363
Query: 1333 A 1333
A
Sbjct: 1364 A 1364
>UniRef50_Q016J3 Cluster: Putative formylglycineamide ribotide am;
n=2; cellular organisms|Rep: Putative formylglycineamide
ribotide am - Ostreococcus tauri
Length = 1078
Score = 575 bits (1420), Expect = e-162
Identities = 311/664 (46%), Positives = 407/664 (61%), Gaps = 32/664 (4%)
Query: 687 RYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALSYYDLVGSATSIGTQNIKGLLDPA 746
R+LT KVDR VTGLVAQQQCVGPL PL+D A+I+ +++D G AT+IG +KGL++P
Sbjct: 436 RFLTTKVDRSVTGLVAQQQCVGPLQVPLSDVAVISQTHFDTKGGATAIGEAPLKGLVNPR 495
Query: 747 AGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEXXXXXXXXXXXXXXMRALGV 806
+ AR+SLGE+LTN+VFA ++ +K SGNWM+A K G + M+ LGV
Sbjct: 496 SMARMSLGESLTNMVFANTQGMDYIKYSGNWMYAAKLGGDGAHMYDACEALCQSMKELGV 555
Query: 807 AVDGGKDSLSMCAHVAGEKVKSPGTLVVSTYAPCPDITVKIEPALKEENS---ALVHAPV 863
A+DGGKDSLSM A GE VK+PGTLV+S Y CPDIT + P LK + LV
Sbjct: 556 AIDGGKDSLSMAAKAGGEVVKTPGTLVMSGYVGCPDITKTVTPDLKLPGTGKLVLVEFGS 615
Query: 864 SPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFI 923
GK R+GGSALAQ Y Q+GD + + TQKL+ E+K+ +GHD+S+GGFI
Sbjct: 616 KEGKRRVGGSALAQAYAQVGDESPDMDDTSYFREAWSATQKLVDERKISAGHDVSDGGFI 675
Query: 924 TTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGIVLEVSKNDLPYVLSEYNNNGVGA 983
T VLEM + V + + + A F EEL IVLEV+ + V+S Y + GV A
Sbjct: 676 TAVLEMAFPSTTA-GVEVTLPGD-DAMSACFAEELAIVLEVAPENEAAVMSAYASVGVTA 733
Query: 984 QHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFRMWEETSYRLECLQANTDCVLQEWKVL 1043
+ I GK D + ++ G + ++ WEE S+ LE LQA+ V E + L
Sbjct: 734 RAI---GKVTNDGKCTVSAAGSECVSDSTANIRDKWEEMSFELEKLQASNATVALEKEGL 790
Query: 1044 EKRKGATYNVTFDPTAAVIKTKS----IKVAVLREEGINGDREMIASLMLANFDVFDVTM 1099
RK T+ +T+ PT + S +KVA++REEG NGDREM A++ A + +DVTM
Sbjct: 791 RSRKAPTWKLTYKPTLTPPEIMSAADKVKVAIVREEGSNGDREMAAAITAAGMEAWDVTM 850
Query: 1100 SDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSL 1159
SDL + + L AFQG+VF GGFSYAD L SAKGWA GI ++ SL QF F DR +TFSL
Sbjct: 851 SDLLSGRANLSAFQGIVFVGGFSYADVLDSAKGWAGGIRYNASLKQQFQDFYDRPNTFSL 910
Query: 1160 GVCNGCQLMAMLGWVDPDSNSKGS--NKAQIFLDHNSSERFECRWSAVKIHENENKEDVW 1217
G+CNGCQLMA+LG++ P G+ + Q HN S RFE RW+ V I +EN +
Sbjct: 911 GICNGCQLMALLGFI-PSEGGVGALPDSKQPRFIHNDSGRFESRWTTVGI--DENTPAMM 967
Query: 1218 FRGMGGSVLGVWVAHGEGRFTVADGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSP 1277
+GMGGS +GVW AHGEG+ D S+L + VD DG PT+ YP+NPNGSP
Sbjct: 968 LKGMGGSRMGVWCAHGEGKVKFPDESMLPDV----------VDADGAPTQQYPLNPNGSP 1017
Query: 1278 DGLAGVRSRDGRHIAMMPHPERCVLRWQCP-APCPTVTNPSVRNSQASPWLRLFQNAYSW 1336
G+AG+ S+DGRH+AMMPHPER + WQ P AP +P PWL++FQNA W
Sbjct: 1018 HGIAGLCSKDGRHLAMMPHPERAFIGWQVPWAPSDAGIDP----YGPGPWLQMFQNAQRW 1073
Query: 1337 AINH 1340
A +H
Sbjct: 1074 ASSH 1077
Score = 396 bits (976), Expect = e-108
Identities = 198/425 (46%), Positives = 282/425 (66%), Gaps = 10/425 (2%)
Query: 35 STELCYHVELAEGCEYLNINQIKVLKWLLSSPLQPQAVRNETIFKSNDNSQLLIEIGPRF 94
++E C++ E G L+ + + WLL +P+ ET ++++ +IE+GPR
Sbjct: 5 TSEQCFNAECVGG---LSDAARETMTWLLRETYEPELF-GETSALVHEDASPVIEVGPRL 60
Query: 95 NFSTADSSNSVQICESVGLRDVVRLEVSTRYLITFGKQKNVTEKHFENLAAVLHDRMTQC 154
F +A S+N+V +C+S GL +V RLE S R+ + + E+ A +HDRMT+C
Sbjct: 61 AFQSAWSTNAVSVCKSCGLENVTRLERSRRFKLYAKDGTTIDEEVRRAFAEAVHDRMTEC 120
Query: 155 VYTKDNLPRKSFNEGLPKDLEPWFVVPLQEQGISAMRKVNDKLGLAFDTWDMEFYMDLFV 214
VY + P K+F + E + VP+ +G +A+ +V+ ++GLAFD D +FYM LF
Sbjct: 121 VYDE---PLKTFELNVTP--EQVYTVPITTEGRAALERVDKEMGLAFDDQDFDFYMRLFC 175
Query: 215 NKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLIDMVASTQKTSN-NNNV 273
+++ RDPT+VELFD+AQSNSEHSRHWFF G+L +DG +I +SL MV T + +N+V
Sbjct: 176 DEIGRDPTNVELFDMAQSNSEHSRHWFFAGELTVDGVKIEKSLFKMVKETIEGDRAHNSV 235
Query: 274 IKFGDNSSAIKGFQHTILRPTNVRGPSQVIQKKTESDIIFTAETHNMPTAVAPFSGATTG 333
I+F DNSSAI+GF +T LRP PS +++K+ + D++ TAETHN P+ VAP+ GA TG
Sbjct: 236 IQFKDNSSAIRGFVNTPLRPAKAGEPSAMVKKEVDLDLLLTAETHNFPSGVAPYPGAETG 295
Query: 334 TGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEAS 393
TGGRIRD G G VAGTAGY GNL + G LP E+ +YPSN A+PLQI+I+AS
Sbjct: 296 TGGRIRDTHATGSGSTLVAGTAGYMTGNLRLDGKVLPHEDMDAKYPSNLASPLQIMIDAS 355
Query: 394 NGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKNKPDKG 453
NGASDYGNKFGEPVI+GF +++G + + R E++KPIMFS G G + H+ ++K + D G
Sbjct: 356 NGASDYGNKFGEPVIAGFCRTFGQRMPNGERREYIKPIMFSAGFGQIDHTNLEKQEGDIG 415
Query: 454 MLLVK 458
ML+VK
Sbjct: 416 MLVVK 420
>UniRef50_Q12AE0 Cluster: Phosphoribosylformylglycinamidine synthase;
n=3; Comamonadaceae|Rep:
Phosphoribosylformylglycinamidine synthase - Polaromonas
sp. (strain JS666 / ATCC BAA-500)
Length = 1375
Score = 566 bits (1398), Expect = e-159
Identities = 423/1334 (31%), Positives = 638/1334 (47%), Gaps = 124/1334 (9%)
Query: 86 LLIEIGPRFNFSTADSSNSVQICESVGLRDVVRLEVSTRYLI-----TFGKQKNVTEKHF 140
+L + PRF + +S + I + GL V R+E T Y + FGK +T+
Sbjct: 81 VLFIVSPRFGTVSPWASKATDIAHNCGLA-VKRIERLTEYRLHLKSGLFGKA-GLTDAQR 138
Query: 141 ENLAAVLHDRMTQCVYTKDNLPRKSFNEGLPKDLEPWFVVPLQEQGISAMRKVNDKLGLA 200
E LAA+LHDRMT+ V F E L+ + + + G +A+ + N + GLA
Sbjct: 139 EQLAALLHDRMTESVMFDRTQAAGLFTELQGAPLQ---TIDVLQGGKAALERANTEFGLA 195
Query: 201 FDTWDMEFYMDLFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLIDM 260
++++ ++ F +LKR+PT VEL AQ+NSEH RH F +DG +SL M
Sbjct: 196 LAADEIDYLVNAFT-QLKRNPTDVELMMFAQANSEHCRHKIFNADFTIDGVPQEKSLFAM 254
Query: 261 VASTQKTSNNNNVIKFGDNSSAIKG------FQHTILRPTNVRGPSQVIQKKTES---DI 311
+ +T+K + V+ + DN+S ++G + + P N + S T+ +
Sbjct: 255 IRNTEKLHPQHTVVAYSDNASVMEGSRVQRFYAKSASSPENTKDESYQSYSATDDVLMHV 314
Query: 312 IFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPW 371
+ ETHN PTA++PF GA+TG GG IRD GRG AG G++V L Y P
Sbjct: 315 LMKVETHNHPTAISPFPGASTGAGGEIRDEGATGRGSRPKAGLTGFTVSRLFDGEYGKP- 373
Query: 372 EEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKPI 431
+ A+PLQI+ E G + + N+FG P ++G+ + Y + R + KPI
Sbjct: 374 --------EHIASPLQIMTEGPLGGAAFNNEFGRPNLAGYFREYE-QTLGGQRWGYHKPI 424
Query: 432 MFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFG 491
M +GG+G + ++ KK G LL++ A+ LDF
Sbjct: 425 MIAGGVGTIDANLTKKILFPAGTLLIQLGGPGMRIGMGGSAASSMASGANAAQ---LDFD 481
Query: 492 AVQRGDAEMGNRLNRVVRGCLE-SDVNPVESIHDQGAGGNGNVLKELVEP--EGAVVFTK 548
+VQRG+ E+ R V+ C + NP+ +IHD GAGG N ELV GA +
Sbjct: 482 SVQRGNPEIERRAQEVINQCAQLGAANPILAIHDVGAGGLSNAFPELVNDAGRGARFDLR 541
Query: 549 EFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGEVTGDGYMSL 608
L + ++ E+W E QE + + + + C RERCP + +G T + + L
Sbjct: 542 AVPLEESGLSPKEIWSNESQERYVMAIAPESLAQFQAFCERERCPFAVIGVATEEKQLVL 601
Query: 609 IE-------------DSYTEK-----FLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTF 650
+ TEK L R + + + D+ + +LG P+
Sbjct: 602 SDAGEPSPQPSPSGRGGQTEKADPSALLPRPFGERAGVRGEAAVDMPMNVLLGKPPKMHR 661
Query: 651 DLQTEKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPL 710
D+++ R+ P+ + ++ ++ VL VASKR+L DR V GL + Q VGP
Sbjct: 662 DVKSLTRSVKPIDLT-GVDLQQSVIAVLSHPTVASKRFLITIGDRTVGGLTHRDQMVGPW 720
Query: 711 HTPLADCAIIALSYYDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELED 770
P+ADCA+ Y G A S+G + ++ AA R+++ EA+TNL+ A I EL
Sbjct: 721 QVPVADCAVTLADYRGFAGEAMSMGERTPLAAVNAAASGRMAVAEAITNLLAAPI-ELPR 779
Query: 771 VKCSGNWMWA-GKTGVEXXXXXXXXXXXXXXMRALGVAVDGGKDSLSMCA-----HVAGE 824
VK S NWM A G+ G + ALGV++ GKDSLSM +GE
Sbjct: 780 VKLSANWMAACGEPGQDAALYETVKAVGMELCPALGVSIPVGKDSLSMRTVWTEDQSSGE 839
Query: 825 --KVKSPGTLVVSTYAPCPDITVKIEPALK--EENSALVHAPVSPGKYRLGGSALAQCYK 880
KV SP +L+VS +A D+ + P L E +++L+ + G+ R+GGS LAQ
Sbjct: 840 RKKVTSPVSLIVSAFATLADVRGTLTPELNTAEADTSLILIDLGKGQNRMGGSILAQTLN 899
Query: 881 QLGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLH 940
+L L K+ ++++ HD S+GG + EM G G++L+
Sbjct: 900 LEDGAVPDLDDPKDLVNLVNAINALRKQGRILAYHDRSDGGLLACCCEMAFAGHVGVSLN 959
Query: 941 V---------------------NVAANVSP------IEALFNEELGIVLEV---SKNDLP 970
V N A+ V ++ALFNEELG V++V ++N++
Sbjct: 960 VDMLLVEGDGISDSRMDAGDSKNWASQVGARREELTLKALFNEELGAVIQVPTEARNEVM 1019
Query: 971 YVLSEYN----NNGVGAQHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFRMWEETSYRL 1026
L E+ ++ +G + +V + + V L D+ ++W+ TS+++
Sbjct: 1020 QTLREHGLSRFSHFIGKTRPQHASLEVGKGEVQVWRDTKAVFGAKLQDLQQVWDNTSWKI 1079
Query: 1027 ECLQANTDCVLQEWKVL--EKRKGATYNVTF--DPTAAVIKTKSIKVAVLREEGINGDRE 1082
+ N C E + G +TF +P A + +VAVLRE+G+N E
Sbjct: 1080 CQQRDNPACADAEHTAVGDPADPGLHVQLTFSPEPRAPGLMLSRPRVAVLREQGVNSHVE 1139
Query: 1083 MIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILFSES 1142
M + A F+ FDV M+DLQ+ + L FQGVV GGFSY DTLG+ GWA I F+
Sbjct: 1140 MAYTFTEAGFEAFDVHMTDLQSGRARLADFQGVVACGGFSYGDTLGAGIGWARSITFNPV 1199
Query: 1143 LSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQIFLDHNSSERFECRW 1202
L+ QF F R DTF LGVCNGCQ+ A L + P + +A N SERFE R
Sbjct: 1200 LAEQFKGFFARPDTFGLGVCNGCQMFAELADIIPGA------EAWPRFTTNRSERFEARL 1253
Query: 1203 SAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLYKNGQVAVQYVDDD 1262
S V++ ++ + ++F+GM GS L + VAHGEG A K A+++ D+
Sbjct: 1254 SMVEVLDSPS---LFFKGMAGSRLPIAVAHGEGYANFAHRGDAGKAI----AAMRFTDNH 1306
Query: 1263 GKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCPAPCPTVTNPSVRNSQ 1322
G+ TE YP NPNGS GL V + DGR AMMPHPER Q ++ +
Sbjct: 1307 GRATETYPANPNGSAGGLTAVTTADGRFTAMMPHPERVFRNVQ-------MSWTMGDKGE 1359
Query: 1323 ASPWLRLFQNAYSW 1336
SPW++L+ NA W
Sbjct: 1360 FSPWMQLWHNARRW 1373
>UniRef50_Q8PCQ7 Cluster: Phosphoribosylformylglycinamidine synthase;
n=7; Xanthomonas|Rep: Phosphoribosylformylglycinamidine
synthase - Xanthomonas campestris pv. campestris
Length = 1348
Score = 544 bits (1343), Expect = e-153
Identities = 417/1314 (31%), Positives = 610/1314 (46%), Gaps = 113/1314 (8%)
Query: 92 PRFNFSTADSSNSVQICESVGLRDVVRLEVSTRYLITFGKQKNVTEKHFENLAAVLHDRM 151
PR + SS + ++ G + + R+E TR + + + +A +LHD M
Sbjct: 77 PRLGTLSPWSSKATELMRGAG-QPIQRVERGTRIDLAGWPEGEADQAA---VAKLLHDPM 132
Query: 152 TQCVYTKDNLPRKSFNEGLPKDLEPWFVVPLQEQGISAMRKVNDKLGLAFDTWDMEFYMD 211
TQ + FN P LE +PL A+ + N LGLA ++++ +
Sbjct: 133 TQSLLGSAAAAEALFNVPDPGQLER---IPLD-----ALEQANGDLGLALAQDEIDYLRE 184
Query: 212 LFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLIDMVASTQKTSNNN 271
F L RDP VEL AQ+NSEH RH F +DGK SL M+ T + + +
Sbjct: 185 RFA-ALGRDPADVELMMFAQANSEHCRHKIFNASWTIDGKPQERSLFRMIKHTHQQTPQH 243
Query: 272 NVIKFGDNSSAIKGFQHTILRPTNVRGPSQVIQKKTESDIIFTAETHNMPTAVAPFSGAT 331
+ + DN++ ++G RP G + + S ETHN PTA+APF GA
Sbjct: 244 TLSAYSDNAAVVEGVPAARFRPDPATGEYRS-EAVVPSAFAIKVETHNHPTAIAPFPGAA 302
Query: 332 TGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIE 391
TG GG IRD GRGG AG G+SV +L IP PWE P A L I+++
Sbjct: 303 TGAGGEIRDEGATGRGGKPKAGLTGFSVSHLRIPTLPQPWEAPRALNP-RMAPALDIMLD 361
Query: 392 ASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKNKPD 451
G + + N+FG P + G+ +S+ L + KPIM +GG+G + + ++K +
Sbjct: 362 GPLGGAAFNNEFGRPNLLGYFRSFELAEGQGLTRAYDKPIMLAGGLGAIDRNQVEKLRLQ 421
Query: 452 KGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGC 511
G ++ D+ + ALDF +VQR + EM R V+ C
Sbjct: 422 PGDAVI--VLGGPAMLIGLGGGAASSVAAGDSAE-ALDFASVQRENPEMERRCQEVIDHC 478
Query: 512 LESDV-NPVESIHDQGAGGNGNVLKELVEPE--GAVVFTKEFQLGDPTITTLELWGAEYQ 568
+ NP+ HD GAGG N + EL+ G V+ DP+++ LELW E Q
Sbjct: 479 VALGTDNPIRWFHDVGAGGLSNAIPELLHDSGVGGVIDLARVPSDDPSLSPLELWCNESQ 538
Query: 569 ENDALLCSKANRHILEEICRRERCPVSFVGEVTGD-----GYMSLIEDSYTE-------K 616
E L +A IC RERCP + VG T + GY + + + E
Sbjct: 539 ERYVLGVPQARLDEFAAICARERCPFAAVGVATAEERLVVGY-GVFDAANRESGIGNRNS 597
Query: 617 FLDRSERLKLES-----KSKLPYDLHLEAVLGNMPRKTFDLQTEKRTKLPLSFPKDITVK 671
L +E S S LP +L ++ + G P+ D + P+ + ++
Sbjct: 598 ALPAAEAASAHSLFPTPDSPLPINLPMDVLFGKAPKMHRDAVHPAAPQWPVLQTGALDLQ 657
Query: 672 SALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALSYYDLVGSA 731
A RVL VASK +L DR V GL A++Q +GP PLADCAI + G A
Sbjct: 658 EAGLRVLAHPTVASKSFLVTIGDRSVGGLTAREQMIGPWQLPLADCAITLAGFETFDGEA 717
Query: 732 TSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWM-WAGKTGVEXXXX 790
SIG + LL+ AA AR+++GEA+TNL A + L+ +K S NWM AG G +
Sbjct: 718 MSIGERTPLALLNAAASARMAVGEAITNLCAAPVQTLDSIKLSANWMAAAGHAGEDALLY 777
Query: 791 XXXXXXXXXXMRALGVAVDGGKDSLSMCAHVA----------GEKVKSPGTLVVSTYAPC 840
AL +++ GKDSLSM A GE + + + P
Sbjct: 778 DAVRAVGMELCPALELSIPVGKDSLSMQAQWQVGNGESGIGNGETPAPSASAIPDSRLPI 837
Query: 841 PDITVK---------------------IEPAL-KEENSALVHAPVSPGKYRLGGSALAQC 878
P T+K + P L +E+ S L + GK RLGGS LAQ
Sbjct: 838 PGETLKSVSPVSLIISAFAPVSDVRTQLTPLLQREDESELWLIGLGGGKQRLGGSVLAQV 897
Query: 879 YKQ------LGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIG 932
Y G + F++ + + L++ HD S+GG + EM
Sbjct: 898 YADDSALPAFGGETPDLDDPQRLRQFFELIRDAREGGLLLAYHDRSDGGAFAALCEMAFA 957
Query: 933 GVRGLNLHVNVAANVSPIEALFNEELGIVLEVSKNDLPYVLSEYNNNGVG--AQHIGY-T 989
+GL++ ++ A +LFNEELG V++++ D + + AQ I T
Sbjct: 958 SRQGLDITLD-AWGDDAFRSLFNEELGAVVQIANEDRAAFADLVERHALTECAQRIARPT 1016
Query: 990 GKYGMDSQVVINLNGVNVLDTVLIDVFRMWEETSYRLECLQANTDCVLQEWKVLE--KRK 1047
G +V ++ G + + +F W ++ ++ L+ N D +E V +
Sbjct: 1017 G----TPRVRVSGQGRVLAEWRWEALFDAWWSVTHAMQKLRDNPDSADEERAVARNFQAP 1072
Query: 1048 GATYNVTFDPT----AAVIKTKS-IKVAVLREEGINGDREMIASLMLANFDVFDVTMSDL 1102
G + FDP+ A + T + KVA+LRE+G+NG EM + A F FDV MSDL
Sbjct: 1073 GLRPKLVFDPSEDVAAPFVATGARPKVAILREQGVNGQIEMAYNFERAGFRAFDVHMSDL 1132
Query: 1103 QNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVC 1162
++ L F G GGFSY D LG+ +GWA IL +L FA F R DTF+LGVC
Sbjct: 1133 IEGRVDLAQFAGFAACGGFSYGDVLGAGRGWATSILERAALRDAFAAFFARSDTFALGVC 1192
Query: 1163 NGCQLMAMLGWVDPDSNSKGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMG 1222
NGCQ+++ L + P G+ FL N SE+FE R + +++ E+ + + RGM
Sbjct: 1193 NGCQMLSQLKDIIP-----GAEHWPRFL-RNRSEQFEARTALLEVVESPS---ILLRGMA 1243
Query: 1223 GSVLGVWVAHGEGRFTVADGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAG 1282
GS + V VAHGEGR + +D+ +VA++++D DG YP+NPNGSPDG+ G
Sbjct: 1244 GSRIPVAVAHGEGR--AEFDTAVDQ--AAARVALRFIDGDGAVASQYPLNPNGSPDGITG 1299
Query: 1283 VRSRDGRHIAMMPHPERCVLRWQCPAPCPTVTNPSVRNSQASPWLRLFQNAYSW 1336
+ S DGR +MPHPER P +P+ + SPWLR+F+NA W
Sbjct: 1300 LTSTDGRATILMPHPER------TPRSVNLSWHPA-GWGEDSPWLRMFRNARVW 1346
>UniRef50_Q9PDF6 Cluster: Phosphoribosylformylglycinamidine synthase;
n=6; Gammaproteobacteria|Rep:
Phosphoribosylformylglycinamidine synthase - Xylella
fastidiosa
Length = 1322
Score = 541 bits (1335), Expect = e-152
Identities = 403/1288 (31%), Positives = 605/1288 (46%), Gaps = 87/1288 (6%)
Query: 92 PRFNFSTADSSNSVQICESVGLRDVVRLEVSTRYLITFGKQKNVTEKHFENLAAVLHDRM 151
PR + SS + ++ G + + R+E TR + G N +A L+D M
Sbjct: 77 PRLGTHSPWSSKTTELLHGAG-QPIARIERGTR-IDLLGWSANAAT--CPAIAKQLYDPM 132
Query: 152 TQCVYTKDNLPRKSFNEGLPKDLEPWFVVPLQEQGISAMRKVNDKLGLAFDTWDMEFYMD 211
TQ + ++ + FN P LE ++ L+ N + GLA +++ Y+
Sbjct: 133 TQSLLESEDEVKTLFNVPEPLSLERIALIDLEH--------ANTRWGLALTADEID-YLR 183
Query: 212 LFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLIDMVASTQKTSNNN 271
+L R P+ VEL AQ+NSEH RH F ++ KE SL M+ T + +
Sbjct: 184 TRYTELNRVPSDVELMMFAQANSEHCRHKIFNATWTINDKEQQHSLFQMIKHTHQHTPQY 243
Query: 272 NVIKFGDNSSAIKGFQHTILRPTNVRGPSQVIQKKTESDIIFTAETHNMPTAVAPFSGAT 331
+ + DN++ I+G RP + G + + ETHN PTA+APF GA+
Sbjct: 244 TLSAYADNAAVIEGHPTARYRPDPITGEYRH-EAVLPGAFQIKVETHNHPTAIAPFPGAS 302
Query: 332 TGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIE 391
TG GG IRD GRGG AG +G+SV +L IP PWE P A+ L I++E
Sbjct: 303 TGAGGEIRDEGATGRGGKPKAGLSGFSVSHLRIPTLPHPWETPRALNP-RMASALDIMLE 361
Query: 392 ASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKNKPD 451
G++ + N+FG P + G+ +S+ L + + KPIM +GG+G + IKK +
Sbjct: 362 GPLGSAAFNNEFGRPNLLGYFRSFELSASKTLTRAYDKPIMLAGGLGAIDRIHIKKLRLQ 421
Query: 452 KGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGC 511
G +++ ALDF +VQR + EM R V+ C
Sbjct: 422 PGDVIIVLGGPAMLIGLGGGAASSVTSGTST---EALDFASVQRDNPEMQRRCQEVIDHC 478
Query: 512 LESDVN-PVESIHDQGAGGNGNVLKELVEPE--GAVVFTKEFQLGDPTITTLELWGAEYQ 568
+ N P+ S HD GAGG N + EL+ G V+ + DP+++ LELW E Q
Sbjct: 479 VALGTNNPIRSFHDVGAGGLSNAIPELLHDSEVGGVIDLAKIPSDDPSLSPLELWCNESQ 538
Query: 569 ENDALLCSKANRHILEEICRRERCPVSFVGEVTGD-----GY-MSL-----IEDSYTEKF 617
E L S A+ IC RERCP + VG T GY ++L + + T +
Sbjct: 539 ERYVLGISAAHLQAFAAICTRERCPFAAVGVATATEQLIVGYGVTLPAALHVTEQQTPQR 598
Query: 618 LDRSER------LKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKRTKLPLSFPKDITVK 671
+ +E L + DL ++ + G P+ + P + +
Sbjct: 599 ANHTETSPTPNTLPPSVREAFAIDLPMDVLFGKAPKMHRNTAHPPPPHWPTLDSTQLDLH 658
Query: 672 SALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALSYYDLVGSA 731
A RVL VA+K +L DR + GL A++Q +GP PLADCAI + G A
Sbjct: 659 HAGLRVLAHPTVAAKNFLVTIGDRSIGGLTAREQMIGPWQLPLADCAITLAGFGTYAGEA 718
Query: 732 TSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGK-TGVEXXXX 790
+IG + LL+ AA AR+++GEA+TNL A + L VK S NWM A + G +
Sbjct: 719 FAIGERAPLALLNSAAAARMAVGEAITNLCAAPVESLSMVKLSANWMAAAEHPGEDALLY 778
Query: 791 XXXXXXXXXXMRALGVAVDGGKDSLSMC----AHVAGEKVKSPGTLVVSTYAPCPDITVK 846
AL +++ GKDSLSM A A SP +LV+S + P D +
Sbjct: 779 DAVKAIGIELCPALDISIPVGKDSLSMQSRWQADGATHTCISPVSLVISAFTPVADARRQ 838
Query: 847 IEPALKEE-NSALVHAPVSPGKYRLGGSALAQCYKQ------LGDNXXXXXXXXXXKSLF 899
+ P L + NS L + GK RLGGS LAQ + G ++ F
Sbjct: 839 LTPLLHHQTNSELWLIALDGGKQRLGGSVLAQVHADSAALPTFGGECPDLDTPETLRAFF 898
Query: 900 KITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHV-NVAANVSPIEALFNEEL 958
+ L++ HD S+GG + EM GL++ N ++ P LFNEEL
Sbjct: 899 ALMNDARNAGLLLAYHDRSDGGAFAALCEMAFASHLGLDITCDNRTEHLFP--HLFNEEL 956
Query: 959 GIVLEVSKNDLPYVLSEYNNNGVGAQHIGYTGKYGMDS---QVVINLNGVNVLDTVLIDV 1015
G +++V+ +G+ A YT + + + I N + +
Sbjct: 957 GAIVQVADEHRTAFTDLVEQHGLTA----YTQRIAHPTTAPSIRIMHNDQCLAQWTWETL 1012
Query: 1016 FRMWEETSYRLECLQANTDCVLQEWKVLEK--RKGATYNVTFDPTAAVIK---TKSIK-- 1068
F W ++ ++ L+ N +C +E ++ G ++FDP V I+
Sbjct: 1013 FDAWWSVTHAMQRLRDNPECADEEREIARTFTAPGLKPTLSFDPAVDVAMPFIATGIRPT 1072
Query: 1069 VAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLG 1128
VA+LRE+GING EM A F D+ M+DL ++ LD F G+ GGFSY D LG
Sbjct: 1073 VAILREQGINGHIEMALCFERAGFHCVDIHMNDLITGRVHLDEFVGLAACGGFSYGDVLG 1132
Query: 1129 SAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQI 1188
+ +GWA IL +L QFA F R D F+LGVCNGCQ+++ L + P G+
Sbjct: 1133 AGRGWATSILERTALRDQFAAFFTRTDRFALGVCNGCQMLSQLKSMIP-----GAEHWPR 1187
Query: 1189 FLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKL 1248
F+ N SE+FE R + +++ ++ + ++ GM GS L V VAHGEG + + D + D+
Sbjct: 1188 FV-RNRSEQFEARTALLEVIQSPS---IFLSGMAGSRLPVAVAHGEG-YAMFD-TPADQ- 1240
Query: 1249 YKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCPA 1308
VA++Y++ G+ YP+NPNGSP+G+ G+ + DGR +MPHPER P
Sbjct: 1241 -AAAHVALRYINGHGQAATHYPLNPNGSPNGITGLTTTDGRITILMPHPER------TPR 1293
Query: 1309 PCPTVTNPSVRNSQASPWLRLFQNAYSW 1336
+P+ + +PWLRLF+NA +W
Sbjct: 1294 TINLSWSPN-EWGEDTPWLRLFRNARAW 1320
>UniRef50_Q2GZN5 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized protein
- Chaetomium globosum (Soil fungus)
Length = 1221
Score = 347 bits (852), Expect = 2e-93
Identities = 263/791 (33%), Positives = 387/791 (48%), Gaps = 57/791 (7%)
Query: 589 RERCPVSFVGEVTG---DGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNM 645
RERC S VG V DG LI R + ++ P LE ++ +
Sbjct: 443 RERCNFSDVGTVLSRERDGVSKLILSDKESNEYPRPIDVPMDVL--FPKGRTLERIVSSK 500
Query: 646 PRK--TFDLQTEKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQ 703
FD ++ + S K A+ RV + V SK +L DR V GL +
Sbjct: 501 KPAWPVFDPVASLKSAIDGSLSDADLFKQAVQRVFWMPAVGSKSFLITIGDRTVGGLTTR 560
Query: 704 QQCVGPLHTPLADCAIIALSYY---DLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNL 760
Q VGP TP+AD A+ A ++ G A ++G + L+ PAA AR+++ E+L NL
Sbjct: 561 DQMVGPWQTPVADVAVTATAFSLNGARTGEAMAMGEKPTLALISPAASARMAVAESLLNL 620
Query: 761 VFAGIS------ELEDVKCSGNWMWA-GKTGVEXXXXXXXXXXXXXXMRALGVAVDGGKD 813
A I +L VK S NWM A G LGV++ GKD
Sbjct: 621 GAADIKGGSHRGDLRRVKLSANWMAAVNHPGEGAALYEAVEAIGMHLCPQLGVSIPVGKD 680
Query: 814 SLSM-CAHVAGEKVKS---PGTLVVSTYAPCPDITVKIEPALKEEN----SALVHAPVSP 865
S SM + GE KS P ++V+S + DI P L+ + L++ ++
Sbjct: 681 STSMKSSWKDGETKKSVTAPVSVVISAFTLVEDIRRTWTPQLRRVEDVGETVLLYVDLAQ 740
Query: 866 GKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITT 925
G+ +GGSALAQ +G K F +L + +++ HD S+GG ITT
Sbjct: 741 GRKAMGGSALAQSLGAIGHEAPDVRDVDLLKDYFDALAQLHESGVVLAYHDRSDGGLITT 800
Query: 926 VLEMGIGGVRGLNLHVN-VAA--NVSP-IEALFNEELGIVLEVSKNDLPYVLSEYNNNGV 981
+ EM G G++L ++ +AA N+S ++ALFNEELG V +V +D + G
Sbjct: 801 IAEMMFAGRCGVDLMMDGIAASGNLSDMVDALFNEELGAVFQVRASDEVNFKRCFATCGP 860
Query: 982 GAQHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFRM---WEETSYRLECLQANTDCVLQ 1038
A I G S+ V+ + V +D M W +TSY ++ L+ C
Sbjct: 861 PAGLIRKFGVVQATSKQVLTIRYGEGAPFVSLDRAEMQQWWTKTSYEMQKLRDTPACAES 920
Query: 1039 EWKVL--EKRKGATYNVTFDPTAAVIK-TKSI--------KVAVLREEGINGDREMIASL 1087
E+ + + G ++N+TF P+ + T SI +VA+LRE+G+NG EM +
Sbjct: 921 EYATILDSEDPGLSFNLTFSPSENITPLTASITGFFGKMPRVAILREQGVNGYAEMAFAF 980
Query: 1088 MLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQF 1147
A FD D+ M+D+ + +L F G+ GGFS+ D LG+ +GWA IL + +
Sbjct: 981 RAAGFDAVDIHMTDIIAGR-SLSDFVGLAACGGFSFGDVLGAGQGWAKSILLHDKARREL 1039
Query: 1148 AHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQIFLDHNSSERFECRWSAVKI 1207
A F +RKDTF+LGVCNGCQ+++ L + G+ F++ N+S +FE R+ VK+
Sbjct: 1040 ADFFNRKDTFALGVCNGCQMLSRLKEL-----ISGAEHFPTFVE-NASSQFEGRFGMVKV 1093
Query: 1208 HENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLYKNGQVAVQYVDDDGKPTE 1267
+N + V+F GM GS L + V+HGEGR A L + G + ++YVD+ TE
Sbjct: 1094 EDNPARPSVFFHGMDGSSLPIVVSHGEGRAEFASDESFRALAEAGGIPLRYVDNRLNVTE 1153
Query: 1268 VYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCPAPCPT-VTNPSVRN-SQASP 1325
YP NPNGSP G+A V SRDGR +AMMPHPER + PA + V + + P
Sbjct: 1154 QYPYNPNGSPGGVAAVSSRDGRVLAMMPHPERNI-----PADVASYVPADEIEEWGEFGP 1208
Query: 1326 WLRLFQNAYSW 1336
WLR+F++A W
Sbjct: 1209 WLRMFRSARRW 1219
Score = 119 bits (287), Expect = 5e-25
Identities = 69/201 (34%), Positives = 103/201 (51%), Gaps = 3/201 (1%)
Query: 146 VLHDRMTQCVYTKDNLPRKSFNEGLPKDLEPWFVVPLQEQGISAMRKVNDKLGLAFDTWD 205
+LHDRMT+ + T F E + LE + + + N GLA D +
Sbjct: 76 ILHDRMTETLSTDAPDLNTMFAESVSAPLEVVNIFENGRDPAQVLNEYNKARGLALDQSE 135
Query: 206 MEFYMDLFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLIDMVASTQ 265
+E+ ++ F +L R P +ELF AQ NSEH RH F +DG ++L +M+ +T
Sbjct: 136 VEYLVEKFT-ELGRPPHDIELFMFAQVNSEHCRHKQFNANWTIDGLAKGKTLFEMIRNTH 194
Query: 266 KTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRGPSQVIQKKTESDIIFTAETHNMPTAVA 325
K + + V + DN++ ++G Q + P G ++ K ++ ETHN PTA+A
Sbjct: 195 KVTPDYTVSAYSDNAAVMEGEQTNLWAPDYSTGSWKL--NKELLHVLAKVETHNHPTAIA 252
Query: 326 PFSGATTGTGGRIRDVQGVGR 346
PF GA TG+GG IRD VGR
Sbjct: 253 PFPGAATGSGGEIRDEGAVGR 273
Score = 81.8 bits (193), Expect = 1e-13
Identities = 54/171 (31%), Positives = 84/171 (49%), Gaps = 13/171 (7%)
Query: 380 SNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTREE-----FVKPIMFS 434
++FA+ L I++EA G++ + N+FG P ++G ++ L AD+T E + KPIM +
Sbjct: 274 AHFASSLDIMLEAPIGSARFNNEFGRPCLAGTFRT--LLTADDTNVEGEFRGYHKPIMIA 331
Query: 435 GGIGYM--PHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGA 492
GG+G + H++ + +G ++ +A LDF +
Sbjct: 332 GGVGTVREKHALKRPEDVTEGAHVIVLGGPAMLIGLGGGAASSNASGEGNAE---LDFDS 388
Query: 493 VQRGDAEMGNRLNRVVRGCLE-SDVNPVESIHDQGAGGNGNVLKELVEPEG 542
VQRG+ EM R V+ C+ D P+ IHD GAGG N L ELV G
Sbjct: 389 VQRGNPEMERRAQMVINTCVALGDQTPIAMIHDVGAGGLSNALPELVRDAG 439
>UniRef50_A7LBA5 Cluster: Truncated formylglycineamide
ribonucleotide synthetase; n=2; Ustilago maydis|Rep:
Truncated formylglycineamide ribonucleotide synthetase -
Ustilago maydis (Smut fungus)
Length = 595
Score = 193 bits (470), Expect = 3e-47
Identities = 135/448 (30%), Positives = 218/448 (48%), Gaps = 27/448 (6%)
Query: 85 QLLIEIGPRFNFSTADSSNSVQICESVGLRDVV-RLEVSTRYLITFGKQKNVTEKHFENL 143
Q ++ + PR + SS + I L+D V R+E Y++ + +
Sbjct: 95 QTVLFVLPRPGSISPWSSKATDIARMCTLKDYVDRIERGVAYVLEPAAATTLEAVDIAQV 154
Query: 144 AAVLHDRMTQCVYTKDNLPRKSFNEGLPKDLEPWFVVPLQ---EQGISAMRKV--NDKLG 198
+LHDRMTQ + F++ P L ++ ++ ++ R V N+KLG
Sbjct: 155 RDLLHDRMTQFISVVPPTADALFHKAQPGALTHVDLLGADGTSDRTVAKQRLVDANEKLG 214
Query: 199 LAFDTWDMEFYMDLFV-------NKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGK 251
LA ++++ +D F+ + L+R+PT VELF AQ NSEH RH F +DGK
Sbjct: 215 LALANDEIDYLVDAFIAGKGDGSDALRRNPTDVELFMFAQVNSEHCRHKIFNADWTIDGK 274
Query: 252 EINESLIDMVASTQKTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRGPSQVIQK-KTESD 310
+ +L M+ +T K + + + DN++ I+G++ T P+ G V Q K
Sbjct: 275 NMPNTLFGMIRNTHKLHPQHTISAYSDNAAVIEGYEATRFAPSPA-GDLAVYQGVKEPMP 333
Query: 311 IIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYD-L 369
+ ETHN PTAV+P+ GA TG+GG IRD VGRG AG G+ NL + G
Sbjct: 334 FLAKVETHNHPTAVSPYPGAATGSGGEIRDEGAVGRGSKPKAGLVGFMTSNLLLEGDGRQ 393
Query: 370 PWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYG----LKNADNTRE 425
PWEE + PS+ ++ I+I+ G+S + N+FG P +SGF +++ + +++
Sbjct: 394 PWEE-DFGKPSHISSAYDIMIDGPLGSSAFNNEFGRPGLSGFWRTWSERIPISESESEVR 452
Query: 426 EFVKPIMFSGGIGYM-PHSMIK-KNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDA 483
+ KPIM +GG+G + P + +K K PD ++++ +
Sbjct: 453 GYHKPIMLAGGLGNVRPKNALKSKITPDAAIIVL----GGPGMLIGLGGGAASSMASGSS 508
Query: 484 RDHALDFGAVQRGDAEMGNRLNRVVRGC 511
ALDF +VQR + EM R +V+ C
Sbjct: 509 SRAALDFASVQRDNPEMQRRCQQVIDAC 536
>UniRef50_A5D2D1 Cluster: Phosphoribosylformylglycinamidine (FGAM)
synthase, synthetase domain; n=1; Pelotomaculum
thermopropionicum SI|Rep:
Phosphoribosylformylglycinamidine (FGAM) synthase,
synthetase domain - Pelotomaculum thermopropionicum SI
Length = 944
Score = 175 bits (425), Expect = 9e-42
Identities = 205/883 (23%), Positives = 344/883 (38%), Gaps = 77/883 (8%)
Query: 82 DNSQLLIEIGPRFNFSTADSSNSVQICESVGLRDVVRLEVSTRYLITFGKQKNVTEKHFE 141
+ +++++E+ + ++++ ++ +G+ +V + Y +GK+ +T E
Sbjct: 77 EGAEVILEVAYKPGVMNPEAASLIKSAADLGISGLVAADSCWEYGF-YGKE--ITGAEIE 133
Query: 142 NLAAVLHDRMTQCVYTKDNLPRKSFNEGLPKDLEPWFVVPLQEQGISAMRKVN-DKLGLA 200
+ L T Y N P G P P ++P++E + +++ DKL L+
Sbjct: 134 RIVNSLLVNAT-VEYVVKNPPTTLIIHGTPG---PTKIIPIREMSDEELIELSRDKLFLS 189
Query: 201 FDTWDMEFYMDLFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLIDM 260
+ +M+ + F ++RDPT E+ +AQ+ SEH H FK +LV+DG E L +
Sbjct: 190 LE--EMKVIQNYFTG-IQRDPTDCEIETIAQTWSEHCVHKTFKARLVVDGIEKKPLLKRL 246
Query: 261 VASTQKTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRGPSQVIQKKTESDIIFTAETHNM 320
+T++ S+ + F DNS ++ + I ETHN
Sbjct: 247 KDATEEISHPLVLSAFVDNSGVMEFYDGMA--------------------ICGKVETHNS 286
Query: 321 PTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPS 380
P+A+ P+ GA TG+GG RD+ G G+G VA T + H P +P G +P
Sbjct: 287 PSAIEPYGGAMTGSGGVFRDIVGTGQGAKVVASTDMFCFAPPHTPREHIP---PGCLHPH 343
Query: 381 NFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKPIMFSGGIGYM 440
++ G DYGN+ G P +G V + R+ KP + G G +
Sbjct: 344 ------YLLRRVVAGVRDYGNRMGIPTNNGSVHFH--------RDFRAKPSVIVGAYGIL 389
Query: 441 PHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRGDAEM 500
P + +K KP+ G L+V R ++ AVQ G
Sbjct: 390 PAAGCRKGKPEAGDLVVALGGRTGRDGIHGATFSSGEMTD---RTIEVNSSAVQIGHPIE 446
Query: 501 GNRLNRVVRGCLESDVNPVESIHDQGAGGNGNVLKELVEPEGAVVFTKEFQLGDPTITTL 560
R+ + D + +I D GAGG + + E+ GA + L ++
Sbjct: 447 EKRMFDAILAA--RDEGLIRAITDCGAGGFASAVGEMGSETGARIALDRAPLKYTGLSPW 504
Query: 561 ELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDR 620
E+ +E QE L + + + L EICR + +GE TGD Y +T +
Sbjct: 505 EILLSESQERMILAVAPEHVNRLFEICRGYNVEATVLGEFTGDHY-------FTATY--- 554
Query: 621 SERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKRTKLPLSFPKDITVKSALDRVLRL 680
+ ++ +L +E + +P++ ++ + +VL
Sbjct: 555 --------EGRVVMNLDMEFLHNGLPQRLLKASWKRPCHAEPGEATTVNWSGLYSQVLSH 606
Query: 681 VNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALSYYDLVGSATSIGTQNIK 740
+NV SK + D V G A G D I+ G S G +
Sbjct: 607 LNVCSKEPIVRLYDHGVQGTNALPPFGGINGDGPNDAVILTPILGKPYGMIISHGLNPVL 666
Query: 741 GLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEXXXXXXXXXXXXXX 800
+DP G+ + EA +N V G + E V N++W
Sbjct: 667 NTIDPYYGSLWAATEAASNAVACGANPNEMVLID-NFIWPFPDEELLGALDMAVDACVDF 725
Query: 801 MRALGVAVDGGKDSLSMCAH-VAGEKVKSPGTLVVSTYAPCPDITVKIEPALKEENSALV 859
RA G+ GKDSLS G +K P L +S + PD++ + KE S +V
Sbjct: 726 ARATGMPFISGKDSLSSTYRGKDGTVIKIPPVLCISAFGRIPDVSRSVSTDFKETGSHIV 785
Query: 860 HAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISE 919
+ GS + G+N K + + + KL++ HDISE
Sbjct: 786 LVGYR-NPNEMAGSVYYEILGATGNN-LPRINMRLLKKVLETVYGAINSGKLLACHDISE 843
Query: 920 GGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGIVL 962
GG ++ EM GG + + + + FNE G L
Sbjct: 844 GGLAASLAEMCFGG--DIGAAIRIPGDEKAENFFFNETAGCFL 884
>UniRef50_P03179 Cluster: Probable membrane antigen P140; n=7;
Lymphocryptovirus|Rep: Probable membrane antigen P140 -
Epstein-Barr virus (strain B95-8) (HHV-4) (Human
herpesvirus 4)
Length = 1318
Score = 171 bits (417), Expect = 8e-41
Identities = 166/628 (26%), Positives = 259/628 (41%), Gaps = 33/628 (5%)
Query: 729 GSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEXX 788
G+ ++G Q K LD G RL++ EAL N A I + EDV + + + +
Sbjct: 703 GTVITLGEQGYKVSLDLREGTRLAMAEALLNAACAPILDPEDVLLTLH-LHLDPRRADNS 761
Query: 789 XXXXXXXXXXXXMRALGVAVDGGKDSLSMCAHVAGEKVKSPGTLVVSTYAPCPDITVKIE 848
R LGV + G S C G + T+V S AP I
Sbjct: 762 AVMEAMTAASDYARGLGVKLTFGSAS---CPET-GSSASNFMTVVASVSAPGEFSGPLIT 817
Query: 849 PALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLKE 908
P L++ S L+ GK + GGS Q + + K+LF+ Q+L+K
Sbjct: 818 PVLQKTGSLLIAVRCGDGKIQ-GGSLFEQLFSDVA-TTPRAPEALSLKNLFRAVQQLVKS 875
Query: 909 KKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGIVLEVSKND 968
++SGHDIS+GG +T ++EM + G RG+ + + VA++ P +F E G+V EV +
Sbjct: 876 GIVLSGHDISDGGLVTCLVEMALAGQRGVTITMPVASDYLP--EMFAEHPGLVFEVEERS 933
Query: 969 LPYVLSEYNNNGVGAQHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFRMWEE-TSYRLE 1027
+ VL + + +G G+ G D + VL L + W S + E
Sbjct: 934 VGEVLQTLRSMNMYPAVLGRVGEQGPDQMFEVQHGPETVLRQSLRLLLGTWSSFASEQYE 993
Query: 1028 CL---QANTDCVLQEWKVLEK-RKGATYNVTFDPTAAVIK-TKSIKVAVLREEGINGDRE 1082
CL + N + ++ E P V + +VAVL G G
Sbjct: 994 CLRPDRINRSMHVSDYGYNEALAVSPLTGKNLSPRRLVTEPDPRCQVAVLCAPGTRGHES 1053
Query: 1083 MIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILFSES 1142
++A+ A V ++++ LD + G+ G D+ + + A I +
Sbjct: 1054 LLAAFTNAGCLCRRVFFREVRDNTF-LDKYVGLAIGGVHGARDSALAGRATVALINRFPA 1112
Query: 1143 LSSQFAHFKDRKDTFSLGVCN-GCQLMAMLGWVDPDSNSKGS------NKAQIFLDHNSS 1195
L F +R DTFS+ + G Q++A LG V N ++ + L N+S
Sbjct: 1113 LRDAILKFLNRPDTFSVALGELGVQVLAGLGAVGSTDNPPAPGVEVNVQRSPLILAPNAS 1172
Query: 1196 ERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLYKNGQVA 1255
FE RW + I + V RG+ G VL WV + + L Q+A
Sbjct: 1173 GMFESRWLNISIPATTS--SVMLRGLRGCVLPCWVQGSCLGLQFTNLGMPYVLQNAHQIA 1230
Query: 1256 VQYVD---DDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCPAPCPT 1312
+ D + YP NP +AG+ SRDGRH+A++ P C WQ P
Sbjct: 1231 CHFHSNGTDAWRFAMNYPRNPT-EQGNIAGLCSRDGRHLALLCDPSLCTDFWQWEHIPPA 1289
Query: 1313 VTNPSVRNSQASPWLRLFQNAYSWAINH 1340
+P + SPW +FQ A+ W++ H
Sbjct: 1290 FGHP----TGCSPWTLMFQAAHLWSLRH 1313
Score = 46.0 bits (104), Expect = 0.007
Identities = 25/56 (44%), Positives = 32/56 (57%)
Query: 668 ITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALS 723
++++S L +L V SK +L DR G VAQQ VGPL PLAD A +A S
Sbjct: 609 LSLESCLTSILSHPTVGSKEHLVRHTDRVSGGRVAQQPGVGPLDLPLADYAFVAHS 664
>UniRef50_Q8BEM8 Cluster: ORF65; n=1; Callitrichine herpesvirus 3|Rep:
ORF65 - Callitrichine herpesvirus 3 (Marmoset
lymphocryptovirus)
Length = 1321
Score = 163 bits (395), Expect = 4e-38
Identities = 161/631 (25%), Positives = 254/631 (40%), Gaps = 34/631 (5%)
Query: 729 GSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEXX 788
G+ +G Q K +L AG +LS+ E++TN FA + +ED+ + ++ + +
Sbjct: 701 GTVMVLGEQGYKSMLSLDAGIKLSIVESVTNAAFAPVKRIEDLLLT-LYLHLDEIETDKN 759
Query: 789 XXXXXXXXXXXXMRALGVAVDGGKDSLSMCAH---VAGEKVKSPGTLVVSTYAPCPDITV 845
R LGV + G S A A ++ T+V S AP
Sbjct: 760 DLGRLLAQTRAYCRELGVRLTIGSASSPRDAREMEFASQEATKFRTVVCSATAPAQFSGY 819
Query: 846 KIEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKL 905
+ PAL+ + L+H V G + GS L Q + + LF ++L
Sbjct: 820 LLTPALRGGGTVLIHVSVEDGP-TIAGSILEQIFAGK-PKIPTIPRVLRVRELFLAIKEL 877
Query: 906 LKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGIVLEVS 965
+ + SGHD+S+GG + +EM + G RG+ ++V + +E +F+E G++ EV
Sbjct: 878 MALGMVESGHDVSDGGVLVCAIEMALAGNRGIK--ISVPEDQDIMEEMFSEAPGVIFEVH 935
Query: 966 KNDLPYVLSEYNNNGVGAQHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFR-MWEETSY 1024
+ L E + A IG G+ G+D + I +G +L I + R W S
Sbjct: 936 RAHAERALKELQGRQLRAFQIGAVGEEGLDKLIEI-YHGQKLLFRQSISLTRGTWSSFSI 994
Query: 1025 R----LECLQANTDCVLQEW--KVLEKRKGATYNVTFDPTAAVIKTKSIKVAVLREEGIN 1078
L NT ++ V+ + T +VAVL G +
Sbjct: 995 EQYNFLRPESVNTSMYAMDYGNPVITLKHPEEEFYTQPLNLVTHPDPRCRVAVLCCPGTS 1054
Query: 1079 GDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGIL 1138
G ++A+ V +++++ D F G+V G D L ++G I
Sbjct: 1055 GSDPLMAAFTNVGCPCVRVLFREVKSEAF-FDQFSGLVIGGACGAQDALTVSRGIVMTIT 1113
Query: 1139 FSESLSSQFAHFKDRKDTFSLGVCN-GCQLMAMLGWVD--PDSNSKGS----NKAQIFLD 1191
L F RK+TFSL V GC + LG V D G+ A++ L
Sbjct: 1114 KKSKLRDALLRFFQRKNTFSLAVGEIGCAIFTGLGIVGSITDYPHPGTPISLESAEVTLA 1173
Query: 1192 HNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLYKN 1251
N S +E RW + I N V R + G +L W+ F + L +
Sbjct: 1174 QNVSTMYESRWLSFSIPPTTNA--VMLRRLRGLILPCWIQGTYLGFNFLTPASPYILQER 1231
Query: 1252 GQVAVQYVDDDGKP---TEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCPA 1308
G A + P + YP NP + +A + S DGRH+AM+ +P C W P
Sbjct: 1232 GLTAAHFHGSGSHPWNTAQHYPRNP-AEANNVAALCSADGRHLAMLFNPSLCTQLWHWP- 1289
Query: 1309 PCPTVTNPSVRNSQASPWLRLFQNAYSWAIN 1339
P T + SPWL FQ A+ WA++
Sbjct: 1290 HIPFQTRSHL---LGSPWLLAFQEAHIWAVS 1317
Score = 47.6 bits (108), Expect = 0.002
Identities = 24/60 (40%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 668 ITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCA-IIALSYYD 726
+ + S L +VL V SK ++ +DRC GL+A Q VGPL P+AD +++ S YD
Sbjct: 609 LCLNSCLTQVLSHPTVGSKEHIVRHMDRCSNGLIALQPGVGPLDIPVADYGFVVSSSIYD 668
>UniRef50_Q1VJH3 Cluster: Phosphoribosylformylglycinamidine
synthase; n=1; Psychroflexus torquis ATCC 700755|Rep:
Phosphoribosylformylglycinamidine synthase -
Psychroflexus torquis ATCC 700755
Length = 412
Score = 159 bits (385), Expect = 6e-37
Identities = 125/426 (29%), Positives = 186/426 (43%), Gaps = 30/426 (7%)
Query: 395 GASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKNKPDKGM 454
G++ Y N+FG P I G+ ++ K F KPIM +GGIG + I+K +P G
Sbjct: 1 GSASYNNEFGRPAIYGYFRTLEYKEYG-----FHKPIMLAGGIGSIKELHIEKGQPKAGD 55
Query: 455 LLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLE- 513
++ ++ LDF +VQR + EM R +V+ E
Sbjct: 56 AVIVLGGPAMLIGLGGGSASSTKKTNENSE---LDFASVQRSNPEMQRRAQQVLDKFNER 112
Query: 514 SDVNPVESIHDQGAGGNGNVLKELVEPE--GAVVFTKEFQLGDPTITTLELWGAEYQEND 571
S NP+ IHD GAGG N + EL + G + ++ D T++ +ELW E QE
Sbjct: 113 SSKNPITFIHDVGAGGISNAIPELAKDTNLGVDIQLEKIYSTDQTMSPMELWCNESQERY 172
Query: 572 ALLCSKANRHILEEICRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSK 631
LE IC+RERCP S G +T + + + KF D E +
Sbjct: 173 VFSIPMKKVPALEFICKRERCPFSIAGTLTDEKVIKI-------KFHD--EEI------- 216
Query: 632 LPYDLHLEAVLGNMPRKTFDLQTEKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTN 691
+L ++ + G++P Q RT + P+ K + VL VASK++L
Sbjct: 217 --VNLSIDDLFGHIPLPELIAQDYDRTSIKEELPES-KFKDKIYNVLSYPVVASKKFLIT 273
Query: 692 KVDRCVTGLVAQQQCVGPLHTPLADCAIIALSYYDLVGSATSIGTQNIKGLLDPAAGARL 751
DR V GLV + Q +G P++D A +Y G +G + L +P A R+
Sbjct: 274 IGDRTVNGLVYRDQLIGNRQIPVSDYAATLDNYDSYSGQVFGVGEKPNIALENPEASTRM 333
Query: 752 SLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEXXXXXXXXXXXXXXMRALGVAVDGG 811
+L E+L N+ + +V S NWM + KT E L V++ G
Sbjct: 334 ALAESLLNICGVLHDSMNEVCFSANWMSSTKTADERGDLLRGVQSLTNMADTLNVSIPVG 393
Query: 812 KDSLSM 817
KDSLSM
Sbjct: 394 KDSLSM 399
>UniRef50_Q0PQQ1 Cluster: Phosphoribosylformylglycinamidine
synthase; n=1; Endoriftia persephone
'Hot96_1+Hot96_2'|Rep: Phosphoribosylformylglycinamidine
synthase - Endoriftia persephone 'Hot96_1+Hot96_2'
Length = 471
Score = 157 bits (382), Expect = 1e-36
Identities = 119/393 (30%), Positives = 174/393 (44%), Gaps = 21/393 (5%)
Query: 145 AVLHDRMTQCVYTKDNLPRKSFNEGLPKDLEPWFVVPLQEQGISAMRKVNDKLGLAFDTW 204
A+LHDRMT+ V + F+ PK P+ V L E G A+ + N +LGLA
Sbjct: 38 ALLHDRMTEVVLAGMDEADCLFSHAEPK---PFTRVDLLEGGRPALERANGELGLALSDD 94
Query: 205 DMEFYMDLFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLIDMVAST 264
++++ ++ F L R+P+ VEL AQ+NSEH RH F ++DG+ SL M+ +T
Sbjct: 95 EIDYLLESFQG-LGRNPSDVELMMFAQANSEHCRHKIFNADWIIDGEPQQRSLFKMIRNT 153
Query: 265 QKTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRGPSQVIQKKTESDIIFTAETHNMPTAV 324
S + + + DN++ + G + P G ++ E I+ ETHN PTA+
Sbjct: 154 TDCSPDGVLSAYKDNAAVMAGPRAERFLPDPKDGVYGFGEE--EIHILMKVETHNHPTAI 211
Query: 325 APFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFAT 384
+P GA TG+GG IRD G+G AG G+SV NL +PG + PWE+ + +
Sbjct: 212 SPDPGADTGSGGEIRDEGATGKGSKPKAGLNGFSVSNLRLPGGEEPWEQDNAQARGVSSR 271
Query: 385 PLQIIIEASNGASDYGNKFGEPVISGFV-------QSYGLKNADNTREEFVKPIMFSGGI 437
P + + P+ + Q +K+ T P GG+
Sbjct: 272 PSISCSKGRSALPPSTTSLVGPICAATSAPTNNGWQGQTVKSCAATTSRSCSP----GGL 327
Query: 438 GYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRGD 497
G + I+K G LV A D LDF +VQR +
Sbjct: 328 GNIRGEHIEKTTFPAGSPLV-VLGGPAMLIGLGGGAASSMASGTSAED--LDFASVQRSN 384
Query: 498 AEMGNRLNRVVRGC-LESDVNPVESIHDQGAGG 529
EM R V+ C NP+ IHD GAGG
Sbjct: 385 PEMERRCQEVIDACWARGGENPILFIHDVGAGG 417
>UniRef50_Q7URX8 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=3; Planctomycetaceae|Rep:
Phosphoribosylformylglycinamidine synthase II -
Rhodopirellula baltica
Length = 1009
Score = 151 bits (365), Expect = 2e-34
Identities = 181/779 (23%), Positives = 294/779 (37%), Gaps = 59/779 (7%)
Query: 180 VPLQEQGISAMRKVNDKLGLAFDTWDMEFYMDLFVNKLKRDPTSVELFDLAQSNSEHSRH 239
VP++E + + K++ + L +M+ D FV +L RDPT +EL +AQ+ SEH H
Sbjct: 194 VPIRELDDAGLEKLSKEGQLYLTLVEMQTIRDHFV-ELGRDPTDIELESVAQTWSEHCSH 252
Query: 240 WFFKGKLVLDGKEINESLIDMVASTQKTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRGP 299
G++ G + + ++ +N F + + + +
Sbjct: 253 KTLAGRIHYKGPGADGT---PGGDERQYNNMLKETIFEATQTIRRSLGDDDWCVSVFKDN 309
Query: 300 SQVIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSV 359
+ ++ + + F ETHN P+A+ P+ GA TG GG IRD G G G V T +
Sbjct: 310 AGIVTFDEQDHVCFKVETHNHPSALEPYGGANTGIGGVIRDPMGTGMGAKPVCNTDVFCF 369
Query: 360 GNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKN 419
P + E P P ++I +G DYGN+ G P ++G V + +
Sbjct: 370 A---------PPDVSPEELPPGVLHPRRVIQGVVSGVRDYGNRMGIPTVNGAVY-FDERY 419
Query: 420 ADNTREEFVKPIMFSGGIGYMPHSMIKKN-KPDKGMLLVKXXXXXXXXXXXXXXXXXXXX 478
N P+++ G +G +P M K KP+ ++ V
Sbjct: 420 LGN-------PLVYCGNVGIIPVGMEDKEVKPNDLIVAV-----GGRTGRDGIHGATFSS 467
Query: 479 XXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLESDVNPVESIHDQGAGGNGNVLKELV 538
+ +L GAVQ G+A + V+ D ++ D GAGG + + E+
Sbjct: 468 AELTSESESLSGGAVQIGNAITEKMVLDVLMQA--RDRGLYNAVTDCGAGGFSSAVGEMG 525
Query: 539 EPEGAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVG 598
E GA V+ + L +T E+W +E QE L + L E+C E + +G
Sbjct: 526 EELGAEVWLDKAPLKYDGLTYTEIWISEAQERMVLAVPQERWDELRELCESEGVEAAAIG 585
Query: 599 EVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKRT 658
G RL+L + D+ + + P D E
Sbjct: 586 RFVPTG------------------RLQLNFHGQTVGDVAMSFLHDGRPPVIRDAIYEPPK 627
Query: 659 KLPLSF-PKDITVKS-ALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLAD 716
PLS +D S L ++L NVASK ++ + D V + VGP D
Sbjct: 628 AKPLSIGDRDAAANSETLLKILGSYNVASKHWVIRQYDHEVQAGSVVKPLVGPQCDGPGD 687
Query: 717 CAIIALSYYDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGN 776
A++ G S G G D A ++ EA+ N V G ++ + N
Sbjct: 688 AAVVRPKLNSRRGLVISCGMNPHYGDFDTYHMAASAIDEAMRNAVAVG-ADPSKIAILDN 746
Query: 777 WMWAGKTGVEXXXXXXXXXXXXXXMR-ALGVAVDGGKDSLSMCAHVAGEK-----VKSPG 830
+ W E + LG GKDSL+ +K + P
Sbjct: 747 FCWGYTDRAETLGSLVRAAIACQDLAVTLGTPFVSGKDSLNNEFSYFDDKNEKQTIAIPP 806
Query: 831 TLVVSTYAPCPDITVKIEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXX 890
+L++S D++ I KE + + V LGGS + G
Sbjct: 807 SLLISAMGQIDDVSKSITMDAKEAGNVIF--LVGETHRELGGSHYGLVENEPG-GAVPEV 863
Query: 891 XXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSP 949
K F + ++ + + S HD+ EGG +EM + G G+NL + + P
Sbjct: 864 DAKLAKKTFATVHQAIQSRLVRSCHDLCEGGLAVAAVEMALAGGLGMNLDLATVSREQP 922
>UniRef50_Q66609 Cluster: Tegument protein; n=1; Equid herpesvirus
2|Rep: Tegument protein - Equid herpesvirus 2 (Equine
herpesvirus 2)
Length = 1319
Score = 149 bits (361), Expect = 5e-34
Identities = 195/804 (24%), Positives = 314/804 (39%), Gaps = 73/804 (9%)
Query: 579 NRHILEEICRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHL 638
NR ILE + + C VS +G + + L +D + + R K Y L +
Sbjct: 545 NRQILEGVFKTFGCRVSLLGHLARAKKIVLYDDRSPD-YCQGGPRYLCFKMHKPRYALPI 603
Query: 639 EAVLGNMPRKTFDLQTEKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVT 698
+ G + P D + L +LR V K Y+ VDRC +
Sbjct: 604 DRWCGTASYRPTAPSRVPYNSSDAGPPSD--AREVLLGILRHPTVGCKNYIVKHVDRCAS 661
Query: 699 G-------------------LVAQQQCVGP--------LHTPLADCAIIALSYYDLVGSA 731
G +V + GP TP + + G
Sbjct: 662 GRVAQQCGVGPLDLPVADYSMVVVEPSAGPPSSMEPWTWETPQVPDDCFLIHEDGVSGVC 721
Query: 732 TSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEXXXXX 791
+++G +N P AGA++++ E++ +L A I+ +EDV + + W G +
Sbjct: 722 SALGEKNSVFPFYPEAGAKMAIAESVLSLALAPIARIEDVTVNLSLAWPHLKGAQGEVFT 781
Query: 792 XXXXXXXXXMRALGVAVDGGKDSLSMCAH-----VAGEKVKSPGTLVVSTYAPCPDITVK 846
A GV+ + + S A G +KS V S +A P K
Sbjct: 782 LLTRCKRFCEDA-GVSCNVTSCASSRRAGGGDPPEGGADIKS---FVASAFAYTPCAFWK 837
Query: 847 IEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLF--KITQK 904
+ P LKE S ++ P SPGK+ A A Y+Q+ + K+ +
Sbjct: 838 LTPDLKEARSVILFLPASPGKH-----AFASVYQQVRGQKKYTGSPVNISGAYLGKLARA 892
Query: 905 LL--KEKKL-ISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGIV 961
+L + K+L +SGHD+ +GG + EM + G+R L++ V V + P+ L +E G+
Sbjct: 893 VLHLRAKRLAVSGHDVGDGGLWAALAEMAMAGMRSLDVEVPVRLDGDPMGFLTSETPGVA 952
Query: 962 LEVSKNDLPYVLSEYNNNGVGAQHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFRMWEE 1021
LEV + + + + +G TG + I +L+ +V W
Sbjct: 953 LEVPLSSASAAVEYLRSKYILCYRVGVTGHKTCERMFRITRGDQVLLECEQEEVGEAWRS 1012
Query: 1022 TSYRLECLQANTDCVLQEWKVLEKRKGATYNVTFDPTAAVIK-TKSIKVAVLREEGINGD 1080
S R+E + E+ + A + + P + + K +VAVL G
Sbjct: 1013 HSVRMERYGPCFNRHAYGEGPYEREREAF--LAYTPFRILNRPNKKHRVAVLLLPGCPYP 1070
Query: 1081 REMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILFS 1140
+ +L + FD V+ DL + + D G+ G + +DT S + ++ S
Sbjct: 1071 LAALDALRDSGFDALAVSHLDLAH--VLTDEVCGLFVAGVDNTSDTKTS-DALTSALVHS 1127
Query: 1141 ESLSSQFAHFKDRKDTFSLGVCN-GCQLMAMLGWVDPD-SNSKGSNKAQIFLDHNSSERF 1198
+ F RKDTFSLGV + C+++ D D + S I S +F
Sbjct: 1128 RN-PGVIRDFLSRKDTFSLGVGSMACRIL-----FDGDMAVSPALQSRDIRCVPAVSCKF 1181
Query: 1199 ECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLYKNGQVAVQY 1258
E RW V I N++ V FR + GS+L W F LD+L +GQ A +
Sbjct: 1182 ESRWLNVFI--NQSTPAVAFRTLRGSLLPCWAQGTHLGFGAPSPECLDRLVASGQAASMF 1239
Query: 1259 VDDD--GKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCPAPCPTVTNP 1316
D P YP NP + +AG+ SRDGRH+ ++ WQ P P P
Sbjct: 1240 YGSDVASGPAMAYPANPTETLP-VAGICSRDGRHLVLLHDITASYYLWQWP-HVPKSNIP 1297
Query: 1317 SVRNSQASPWLRLFQNAYSWAINH 1340
SPW ++F + ++W H
Sbjct: 1298 IA----VSPWKQVFYDLHAWVTAH 1317
>UniRef50_Q73N76 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=1; Treponema denticola|Rep:
Phosphoribosylformylglycinamidine synthase II -
Treponema denticola
Length = 766
Score = 146 bits (354), Expect = 4e-33
Identities = 198/806 (24%), Positives = 309/806 (38%), Gaps = 68/806 (8%)
Query: 200 AFDTWDMEFYMDLFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLID 259
A D ++M + + + KR T E +AQ+ SEH H FK K+ +DG + E
Sbjct: 16 ALDIYEMRAIREFYKTE-KRPCTDAEFETIAQTWSEHCVHKTFKAKIDIDGTSLTEEQKK 74
Query: 260 MVASTQKTSNNNNVIKFGDNSSAIKGFQHTILRP---TNVRGPSQVIQKKTESDIIFTAE 316
N++IK + IK I P ++ + +I+ + ++ F AE
Sbjct: 75 AYPGLCV----NSIIK-----TYIKKATDDIDAPWVLSSFVDNAGIIEFDEKYEVSFKAE 125
Query: 317 THNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGW 376
THN P+A+ PF GA TG GG IRDV GV A T G+ P ++P KG
Sbjct: 126 THNHPSAIEPFGGANTGVGGVIRDVMGV--SARPFAVTDVLCFGHPDTPAENVP---KGT 180
Query: 377 EYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKPIMFSGG 436
+P +II G DYGNK G P ++G V Y A N P+++ G
Sbjct: 181 LHPK------RIISGVIEGVKDYGNKMGIPTVNGGVH-YHEAYASN-------PLVYCGC 226
Query: 437 IGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRG 496
G P + KP G ++ DA + +VQ G
Sbjct: 227 AGIAPRGK-HRTKPSAGDHII---SLGGKTGRDGLRGATFSSMVMDASTGDVAGSSVQIG 282
Query: 497 DAEMGNRLNRVVRGCLESDVNPVESIHDQGAGGNGNVLKELVEPEGAVVFTKEFQLGDPT 556
+ + ++ V+ D +I D GAGG + + E+ G V + +
Sbjct: 283 EPIIQKKVAEVLIDA--RDQGLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQG 340
Query: 557 ITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGEVTGDGYMSLIEDSYTEK 616
+ ELW +E QE + L+++C ++ +G TGD +
Sbjct: 341 LAPWELWLSEAQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVL---------- 390
Query: 617 FLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKRTKLPLSFP--KDITVKSAL 674
R++ K + +L + P++ K K + +P K+ + +AL
Sbjct: 391 ------RVRFGEKEII--NLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAAL 442
Query: 675 DRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAII-ALSYYDLVGSATS 733
V+ V SK + D V G + GP D A+I + A S
Sbjct: 443 KAVINHHAVNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVAIS 502
Query: 734 IGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEXX-XXXX 792
+GLLDP A A ++ EA+ N V AG ++ E N+ E
Sbjct: 503 NALNPRQGLLDPYAAAASAIDEAVRNAVAAG-ADPEKTAILDNFCLGDPNRPETMWALIE 561
Query: 793 XXXXXXXXMRALGVAVDGGKDSL-SMCAHVAGEKVKSPGTLVVSTYAPCPDITVKIEPAL 851
GKDS + G++V P +L++S PDI
Sbjct: 562 MARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPPSLLISAMGIVPDIGRVPGSDF 621
Query: 852 KEENSALVHAPVSPGKYRLGGSALAQCYK-QLGDNXXXXXXXXXXKSLFKITQKLLKEKK 910
K+E SA+ V ++ GGS A+ + G++ L+K + +
Sbjct: 622 KKEGSAIY--LVGKPQFSFGGSVFAELFGIPSGESAAVPPFKKEAAELYKKLHSNIMKGL 679
Query: 911 LISGHDISEGGFITTVLEMGIGGVRG-LNLHVNVAANVSPIEALFNEELGIVLEVSKNDL 969
++S HD+SEGG + EM + G+ L + S I +LF E G +L K +
Sbjct: 680 VLSCHDLSEGGLAAALYEMCLSGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEEN 739
Query: 970 PYVLSEYNNNGVGAQHIGYT-GKYGM 994
E G IG T GK G+
Sbjct: 740 RSAF-EKEMEGASIYEIGKTCGKAGL 764
>UniRef50_Q3ZZB9 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=4; Bacteria|Rep: Phosphoribosylformylglycinamidine
synthase II - Dehalococcoides sp. (strain CBDB1)
Length = 953
Score = 146 bits (353), Expect = 5e-33
Identities = 183/728 (25%), Positives = 274/728 (37%), Gaps = 66/728 (9%)
Query: 216 KLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLIDMVASTQKTSNNNNVIK 275
KL R PT EL LAQ+ SEH H FK L DG+ IN L +A N +
Sbjct: 204 KLGRAPTDAELETLAQTWSEHCCHKTFKAMLDYDGQIINNLLKQTIAKATAELNKPWCLS 263
Query: 276 -FGDNSSAIKGFQHTILRPTNVRGPSQVIQKKTESDIIFTAETHNMPTAVAPFSGATTGT 334
F DNS VI+ E + F AETHN P+AV P+ GA TG
Sbjct: 264 VFVDNSG--------------------VIEFNDEWGVCFKAETHNHPSAVEPYGGAATGI 303
Query: 335 GGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASN 394
GG IRD+ G G +A T + G P DL E+K P P ++ +
Sbjct: 304 GGVIRDILGTGLAAKPIANTDVFCFGP---P--DLA-EDK---LPPGVLHPRRVFKGVRS 354
Query: 395 GASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKNKPDKGM 454
G +DYGN+ G P ++G V L + T P+++ G IG +P K G
Sbjct: 355 GVADYGNRMGIPTVNGAV----LFDERYT----ANPLVYCGTIGLIPKKYALPGKQSAGD 406
Query: 455 LLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLES 514
L+V + R L F AVQ G+A + R+ + +
Sbjct: 407 LVV---LIGGRTGRDGIHGVTFASGELNDRSTELSFTAVQIGNAIVEKRMLDTLLQARDR 463
Query: 515 DVNPVESIHDQGAGGNGNVLKELVEPEGAVVFTKEFQLGDPTITTLELWGAEYQENDALL 574
++ I D G GG + + E+ E G ++ + L +T E+W +E QE L
Sbjct: 464 EL--FVRITDCGGGGLSSAVGEMAESTGVKIYLDKVPLKYSGLTYSEIWISESQERMLLA 521
Query: 575 CSKANRHILEEICRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPY 634
+K + + E S +GE T D ++ L + L ++ +
Sbjct: 522 VNKEKLGEILALFESEGVEASVIGEFTSDRHLKLFYQDHQVADL----QMNFLHNGRPQL 577
Query: 635 DLHLEAVLGNMPRKTFDLQTEKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVD 694
+L P FD PKD ++ L +L NV S+ ++ + D
Sbjct: 578 ELRATHHKTRHPEADFDC------------PKDF--ETELKNILSHWNVCSREWIIRQYD 623
Query: 695 RCVTGLVAQQQCVGPLHTPLADCAIIALSYYDLVGSATSIGTQNIKGLLDPAAGARLSLG 754
V G + VG + D A+I S G +D A ++
Sbjct: 624 HEVQGGSVLKAMVGAENDGPGDAAVIRPVLGSKKAVVISNGINPSYADVDAYNMAASAID 683
Query: 755 EALTNLVFAGISELEDVKCSGNWMWAGKTGVEXXXXXXXXXXXXXXMRAL-GVAVDGGKD 813
EAL ++ G LE V N+ W + E + + G GKD
Sbjct: 684 EALRQIIAVG-GNLERVALLDNFSWGNASRPESLGDLVHACQACHDLSLVFGTPFISGKD 742
Query: 814 SLSMCAHVAGEKVKSPGTLVVSTYAPCPDITVKIEPALKEENSALVHAPVSPGKYRLGGS 873
SL+ + + P TL++S D I K+ + L++ V LGGS
Sbjct: 743 SLNNEFRYEDKLITIPHTLLISAIGVMEDGDKAISMDFKKSGN-LIYI-VGKTAEELGGS 800
Query: 874 ALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGG 933
+ + +G N K + + + HD+SEGG T EM G
Sbjct: 801 HYFKNHSFIG-NRAPAVNAKRAKENMQALSCATAGGLVAACHDLSEGGLGVTAAEMAFSG 859
Query: 934 VRGLNLHV 941
G ++ +
Sbjct: 860 KLGAHIRL 867
>UniRef50_Q53CQ9 Cluster: JM161; n=3; Cercopithecine herpesvirus
17|Rep: JM161 - Macaca fuscata rhadinovirus
Length = 1298
Score = 145 bits (352), Expect = 6e-33
Identities = 155/640 (24%), Positives = 260/640 (40%), Gaps = 44/640 (6%)
Query: 728 VGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEX 787
VG + G Q K +D A GAR ++ EA+TN++ A + L D+ + + W + +
Sbjct: 674 VGQCVAHGEQAYKMGIDAAVGARYAICEAVTNIMLAHVRRLSDITLTASVGWNPEED-QA 732
Query: 788 XXXXXXXXXXXXXMRALGV--AVD--GGKDSLS--MCAHVAGEKVKSP---GTLVVSTYA 838
R L V A+ G LS + + + +P ++++ A
Sbjct: 733 WLLQHALFACKELCRDLSVNFAITSAGSTPCLSEELISATQQHQTVAPVPFNAVIITATA 792
Query: 839 PCPDITVKIEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSL 898
++ P LK + LV PG + GS L +L
Sbjct: 793 EVKSSRRRVTPDLKATGNLLVLVTF-PGPHLTQGSTFEHLCL-LPSPTLPDVQATHLANL 850
Query: 899 FKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEEL 958
F +T+ +L ++SGHD+S+GG + T +EM + G RGL + + + +P+ L +E
Sbjct: 851 FMLTESMLSRGLVVSGHDVSDGGVVVTAIEMALAGNRGLQ--ICIPSEETPLPWLVSETP 908
Query: 959 GIVLEVSKNDLPYVLSEYNNNGVGAQHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFRM 1018
G++ E+ + V N A G G+ G+ ++VI+ N V L V
Sbjct: 909 GVIFEILPQHVDEVRQACQNFDCQATVCGTVGQEGLSERIVISHNNEEVYSQTLTSVAAN 968
Query: 1019 WEETSYRLECLQANTDCVLQEWKVLEKRKGAT-YNV--------TFDPTAAVIKTKSIKV 1069
W TS+ E + ++ K G +N+ + T + ++ V
Sbjct: 969 W--TSFSDEQWYSWGPSFTPAQELYRKDYGCNRHNLGHLADVCRNSELTLFAVPSRPPAV 1026
Query: 1070 AVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGS 1129
A L G R ++A+ FDV V+ +DL+ I L F G+ G D+
Sbjct: 1027 AALIAPGAPLPRALMAAFTNVGFDVAAVSTNDLRGGNI-LRGFSGLTIGGNVGIEDSYVG 1085
Query: 1130 AKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCN--GCQLMAMLGWVDPDSNS----KGS 1183
A+ G+L F R DTFSL C G QL+ LG + + K
Sbjct: 1086 ARCAIMGLLNDPGCYGGLMAFFRRADTFSL-CCGEFGFQLLGALGLLRETPHDTPGPKTP 1144
Query: 1184 NKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGS 1243
++ I L+ N+S EC W + +H + + FR + G VL W +
Sbjct: 1145 DQWDIHLEENASGNHECLW--LNLHIPQTTISIMFRVLRGLVLPGWANGRYLGVRYPRDA 1202
Query: 1244 LLDKLYKNGQVAVQYVDDDGKP---TEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERC 1300
+ L + ++A+ + + P + YP NP+ + +A + S DGRH+A + P
Sbjct: 1203 IEYHLNQQQRIALNFHTGNPDPRMFAQHYPRNPSAN-SAVAAITSPDGRHLASLVDPAVV 1261
Query: 1301 VLRWQCPAPCPTVTNPSVRNSQASPWLRLFQNAYSWAINH 1340
WQ A P P + + SPW FQ+ + W + +
Sbjct: 1262 FHPWQW-AYVP----PELADMTISPWALAFQSLFLWCVRN 1296
Score = 53.2 bits (122), Expect = 5e-05
Identities = 26/49 (53%), Positives = 33/49 (67%)
Query: 672 SALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAII 720
S +D++LR V SK ++T VDRC GLVAQQ VGPL PL+D I+
Sbjct: 579 SVVDQLLRCPTVGSKEFVTRHVDRCSNGLVAQQCEVGPLGRPLSDYHIV 627
>UniRef50_A5D2D2 Cluster: Phosphoribosylformylglycinamidine (FGAM)
synthase, glutamine amidotransferase domain; n=1;
Pelotomaculum thermopropionicum SI|Rep:
Phosphoribosylformylglycinamidine (FGAM) synthase,
glutamine amidotransferase domain - Pelotomaculum
thermopropionicum SI
Length = 260
Score = 142 bits (344), Expect = 6e-32
Identities = 85/243 (34%), Positives = 131/243 (53%), Gaps = 11/243 (4%)
Query: 1065 KSIKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYA 1124
K +V +++ +GIN D E + + A + V ++ L+ + L ++Q + PGGFSY
Sbjct: 2 KKPRVCIMKTDGINCDEETYYAFVKAGAECRIVHVNQLRKGEEKLASYQILALPGGFSYG 61
Query: 1125 DTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSN 1184
D + S K A + + L Q F + +G+CNG Q++ G + P+ N
Sbjct: 62 DDVHSGKILAVEL--TSFLKDQLKEFVNAGKLI-IGICNGFQVLVRTGLL-PEQNLD-CI 116
Query: 1185 KAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSL 1244
K + + N S FECRW + + N V+ +G+ G+V+ V VAHGEG+F D +
Sbjct: 117 KTTLMV--NDSGHFECRWVNLLVEHNHC---VFTKGLEGTVISVQVAHGEGKF-YTDPAT 170
Query: 1245 LDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRW 1304
L ++ GQV +Y DG+PT +YP NPNGS + +AG+ GR + MMPHPER V +
Sbjct: 171 LQEIENRGQVVFRYAGTDGRPTVLYPYNPNGSLNAIAGICDSTGRIMGMMPHPERYVEKT 230
Query: 1305 QCP 1307
Q P
Sbjct: 231 QHP 233
>UniRef50_Q99D25 Cluster: V-FGAM-synthase; n=1; Bovine herpesvirus
4|Rep: V-FGAM-synthase - Bovine herpesvirus 4 (BoHV-4)
(Movar virus)
Length = 1288
Score = 141 bits (342), Expect = 1e-31
Identities = 146/602 (24%), Positives = 247/602 (41%), Gaps = 31/602 (5%)
Query: 745 PAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEXXXXXXXXXXXXXXMRAL 804
P GA +++ E+L N+V A ++DV C+ N W T + L
Sbjct: 686 PIKGAHVAIVESLLNIVSAPFKRIDDVTCTFNITWPQTTDSHFGILELMRAGREFCSQ-L 744
Query: 805 GVAVDGGKDSLSMCAHVAGEKVKSPGT---LVVSTYAPCPDITVKIEPALKEENSALVHA 861
G+ G + ++ G+K + L V+ APC D+T + P LKE +S++V
Sbjct: 745 GI---GCVFTSCTTSNRRGQKCLNNSLVRYLTVTATAPCKDVTQGLTPDLKEPDSSIVWL 801
Query: 862 PVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGG 921
P+S +Y G+ ++Q ++ K L +T+ L+ + +IS HD+ GG
Sbjct: 802 PIST-EYHTFGTVISQLFRDSPSGHIINIDPLYVKKLITVTKHLINHESIISCHDVGCGG 860
Query: 922 FITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGIVLEVSKNDLPYVLSEYNNNGV 981
IT EM G G ++ + V + P+ L +E G+++EV + + V + +
Sbjct: 861 LITACFEMAYAG--GASIALTVPQDEDPVLFLTSETPGLMVEVPRVKVSTVQKHLETSDI 918
Query: 982 GAQHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFRMWEETSYRLECLQANTDCVLQEWK 1041
+G T + ++ + L ++ W S + + C Q
Sbjct: 919 IYFDVGRTLPSVASNTFTVSYKERIIFRESLNEMVENWRHFSTKEQ--MRTYPCEYQGTP 976
Query: 1042 VLEKRKGATYNVTFDPTAAVI-KTKSIKVAVLREEGINGDREMIASLMLANFDVFDVTMS 1100
+ K ++TF P+ K +V V G N ++ +L A F V V+
Sbjct: 977 E-DPPKDLQLHLTFQPSMCPHGPYKYHQVNVYLLPGTNTPDSLLVALEEAGFRVNLVSTF 1035
Query: 1101 DLQNKKITLDAFQ--GVVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFS 1158
+ KI D G+ G + D K + + L + + D FS
Sbjct: 1036 TDKTVKIVTDTTNVFGICLIGATNIEDATLGDKAISMYTKHNSVLVGELKKLINSPDVFS 1095
Query: 1159 LGVCN-GCQLMAMLGWVDPDSNSKGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVW 1217
L + + CQ++ ++ +K SN ++ N S E RW I EN + V
Sbjct: 1096 LAIGHTACQILFENKFM---GYNKPSN-TTMYCKENYSGLMESRWLNFFIPENTHA--VA 1149
Query: 1218 FRGMGGSVLGVWVAHGEGRFTVADGSLLDKLYKNGQVAVQY--VDDDGKPTEVYPMNPNG 1275
+ M GS+L W+ F + ++ L +G VA Q+ D P YP NP
Sbjct: 1150 LQSMKGSLLPGWIQGTHLGFAHPSETYMEMLSTHGMVATQFYGADISAGPALTYPQNPTA 1209
Query: 1276 SPDGLAGVRSRDGRHIAMMPHPERCVLRWQCPAPCPTVTNPSVRNSQASPWLRLFQNAYS 1335
++G+ S DGRH+A++ P WQ P P +T P + SPW R+F + +
Sbjct: 1210 GYT-ISGLCSADGRHLALLHDPGLSNNLWQWP-HIPKMTPP----LKVSPWKRMFLDLHI 1263
Query: 1336 WA 1337
WA
Sbjct: 1264 WA 1265
>UniRef50_Q99CW7 Cluster: Tegument protein/v-FGAM-synthetase; n=3;
Bovine herpesvirus 4|Rep: Tegument
protein/v-FGAM-synthetase - Bovine herpesvirus 4 (BoHV-4)
(Movar virus)
Length = 1305
Score = 138 bits (333), Expect = 1e-30
Identities = 156/640 (24%), Positives = 264/640 (41%), Gaps = 46/640 (7%)
Query: 730 SATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEXXX 789
S +IG Q K + P GA+ +L E LTN+VF+ + LE + S + W T +
Sbjct: 681 SVMAIGEQGYKMINYPTTGAKYALCELLTNMVFSPVDTLEHIDISASVCW-DPTPSKLSV 739
Query: 790 XXXXXXXXXXXMRAL--GVAVDGGKDSLSMCAHVAGEKVKSP-------GTLVVSTYAPC 840
R L G++ DS+ M + + T+V + A
Sbjct: 740 LHQTMFTCKEFCRDLNIGLSFTSASDSIPMGEGESMDPTAMDLGIPTFINTMVFTGSARV 799
Query: 841 PDITVKIEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFK 900
P T ++ P LK S+L+ +S + L GS + + + ++LF
Sbjct: 800 PSHTDRVTPELKMNGSSLICLSIS-NQVTLAGSTFEHIFTEQIE-ALPDVSSSQIRNLFY 857
Query: 901 ITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGI 960
+ +KL+ E ++SGHDIS+GG + VLEM + G +G+ + + A +P LF+E G+
Sbjct: 858 LVKKLMSENLILSGHDISDGGLLVCVLEMALAGAKGVT--ITIPAQENPNRILFSEIPGV 915
Query: 961 VLEVSKNDLPYVLSEYNNNGVGAQHIG-YTGKYGMDSQVVINLNGVNVLDTVLIDVFRMW 1019
V+E + D+P + S + IG G ++++ I + L ++ W
Sbjct: 916 VIEAQRTDIPRIFSISREFECISHDIGSVDGSSPDNNRLTIKQEQTIIYRNSLTSLYNDW 975
Query: 1020 ----EETSYRLECLQANTDCVLQEWKVLEKRKGATYN---VTFDPTAAVIKTKSIKVAVL 1072
++T + D + ++ + Y D +K VA L
Sbjct: 976 CFFADDTFSKFAKEFTPVDEIYRKDYGNNQINLHPYKDQCTHCDLCLYTSPSKPCTVAAL 1035
Query: 1073 REEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKG 1132
G I++ F V+ +T +L K TL++F G++ G + A+
Sbjct: 1036 VFPGCPIPHAAISAFTNVGFQVYIITYYELL-KGQTLNSFDGLIIGGSCGSQSSYMGARA 1094
Query: 1133 WAAGILFSESLSSQFAHFKDRKDTFSLGVCN--GCQLMAMLGWV-DPDSNSKGSNKAQ-- 1187
++++ +Q F +R DTFSLG C G QL+ + V P S + Q
Sbjct: 1095 NIMAATANDNVRTQLIGFFNRPDTFSLG-CGEIGFQLLVAMNAVGTPQSPTTQDINLQEP 1153
Query: 1188 --IFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWV--AHGEGRFTVADGS 1243
I L+ N+S+ +E RW + + + + +VL W H R+ DG
Sbjct: 1154 WPIELEQNASQLYEARW--LNTYIPLMNRSIMLSVLKNTVLPCWAFGTHLGVRYN-RDG- 1209
Query: 1244 LLDKLYKNGQVAVQYVDDDGKP---TEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERC 1300
L +L ++G VA+ + P + YP NP + +AG+ S DGRH+A +
Sbjct: 1210 LEYQLRESGLVALTFHGPSSDPNNYAQHYPRNPTAN-SHVAGITSPDGRHLATIVDISLV 1268
Query: 1301 VLRWQCPAPCPTVTNPSVRNSQASPWLRLFQNAYSWAINH 1340
WQ P P + SPW FQ + W + +
Sbjct: 1269 FHPWQW-QHIPKNNVP----LKTSPWALAFQCLFLWCLKN 1303
Score = 49.2 bits (112), Expect = 8e-04
Identities = 24/55 (43%), Positives = 35/55 (63%)
Query: 669 TVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALS 723
+++S + +VL+ V SK Y+ +DR GLVAQQ VGPL P++D +II S
Sbjct: 578 SLQSTISQVLKHPTVGSKEYIVRHIDRGSNGLVAQQAGVGPLDVPVSDYSIICES 632
>UniRef50_A1BM63 Cluster: Phosphoribosylformylglycinamidine
synthase-like protein; n=9; Rhadinovirus|Rep:
Phosphoribosylformylglycinamidine synthase-like protein -
Ovine herpesvirus 2
Length = 1316
Score = 138 bits (333), Expect = 1e-30
Identities = 149/641 (23%), Positives = 261/641 (40%), Gaps = 45/641 (7%)
Query: 726 DLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGV 785
++ + ++G Q ++ P GA ++ E LTNL+ LE++ + + W
Sbjct: 694 NMPATCLALGEQALRIASAPVEGAIWAIAELLTNLMMGPRISLENLIITASATWDPTGNP 753
Query: 786 EXXXXXXXXXXXXXXMRALGVAVDGGK-----DSLSMCAHVAGEKVKSPGTLVVSTYAPC 840
E V DS + +H G+ +K +V S
Sbjct: 754 EELKQTLLACKAYAQELNANFVVSSASSSAPPDSRYLDSHPEGKPLKFFKNIVFSGACKV 813
Query: 841 PDITVKIEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFK 900
+ + P L++ +ALVH ++P + L GS Y L +LF
Sbjct: 814 TSLHRTV-PVLQKPGNALVHLSINPA-WGLTGSVFESLYG-LKLGTVEKIPAPKLAALFS 870
Query: 901 ITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGI 960
I Q+ ++ +++SGHDIS+GGF+ ++LE+ + + + P+ LF+E G
Sbjct: 871 IVQEYIEADRVVSGHDISDGGFVASLLELCFS--TEYTVRITLPPEYQPVAYLFSEAPGA 928
Query: 961 VLEVSKNDLPYVLSEYNNNGVGAQHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFRMW- 1019
VLE+ + LP +L G+ + IGY + ++ G + + + + W
Sbjct: 929 VLELDIHHLPSLLXRCQKAGIYCKEIGYIST-SEKGALSLSHRGKVIFEQQIASLRSTWS 987
Query: 1020 --EETSYRLECLQANTDCVLQ-EWKVLEKRKGATYNVTFDPTAAVIKTKSI--KVAVLRE 1074
+T + D + + ++ E G D A + I KVAVL
Sbjct: 988 HHSDTFFAKFSNDLEEDSMYKHDYGANEVDFGDLRQQLLDNYVAFYHSPDIRSKVAVLTW 1047
Query: 1075 EGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWA 1134
G+ + + + + FDV+ V + ++ + K LD F+G+ G D +A
Sbjct: 1048 PGMVKEESLTWAFTNSQFDVYTVCVQEINDPKF-LDEFRGLAIGSGSGCMDPQLAAGAAV 1106
Query: 1135 AGIL----FSESLSSQFAHFKDRKDTFSLGVCN------GCQLMAMLGWVDPDSNSKGSN 1184
+L ++ LS+ FK R +TFSLG C Q + L P ++ S
Sbjct: 1107 KALLEAPGYNVVLSALLRFFK-RPNTFSLG-CGEFGFIVASQFIHNLNSAAPGPSTSHS- 1163
Query: 1185 KAQI---FLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVAD 1241
K Q+ L+ N S +E RW +V++ +E+ + G VL WV + +
Sbjct: 1164 KLQLTPFTLEKNKSGVYESRWLSVRV--SESSPSIMLTPCRGMVLPCWVQGTYLGLSYSA 1221
Query: 1242 GSLLDKLYKNGQVAVQYVDDDGKP---TEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPE 1298
+ L++ VA Y P YP NP+G+ +AG+ S DGRH+A++ P
Sbjct: 1222 DGVEHSLFQTNTVACSYHGQSKTPEAFARHYPRNPSGN-SSVAGLCSNDGRHLALLFDPS 1280
Query: 1299 RCVLRWQCPAPCPTVTNPSVRNSQASPWLRLFQNAYSWAIN 1339
+Q P + + SPW LF ++W ++
Sbjct: 1281 LAFFPFQWQH-----LPPEYKQLKTSPWSLLFYQMHNWCLS 1316
Score = 49.2 bits (112), Expect = 8e-04
Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 14/145 (9%)
Query: 582 ILEEICRRERCPVSFVGEVTGDGYMSLIED-----SYTEKFLDRSERLKLESKSKLPYDL 636
IL+++ R C V +GE D + + D YT K ++ + S+ P L
Sbjct: 518 ILQQVARLYGCTVHILGETVPDTGIHVWNDLATPFDYTAKHHKGVKKYSIHQYSEEPRPL 577
Query: 637 HLEAVLGNMPRKTFDLQTEKRTKLP-LSFPKDITVKSALDRVLRLVNVASKRYLTNKVDR 695
R+ D E P ++ + + + +L V SK Y+ + +DR
Sbjct: 578 --------TSRQDTDPDLECTVIAPSFNWAEGFVLNECVQNILLNPTVGSKSYIVHHMDR 629
Query: 696 CVTGLVAQQQCVGPLHTPLADCAII 720
C GLV QQ VGP PLAD ++
Sbjct: 630 CGNGLVVQQPGVGPFDLPLADYGLV 654
>UniRef50_Q1Q6R2 Cluster: Similar to phosphoribosylformylglycinamidine
synthase I; n=1; Candidatus Kuenenia stuttgartiensis|Rep:
Similar to phosphoribosylformylglycinamidine synthase I -
Candidatus Kuenenia stuttgartiensis
Length = 261
Score = 136 bits (328), Expect = 5e-30
Identities = 88/243 (36%), Positives = 130/243 (53%), Gaps = 11/243 (4%)
Query: 1065 KSIKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYA 1124
K+ K+ VLR G N D E + A + ++ L + K L+ +Q + PGGF+Y
Sbjct: 2 KTPKILVLRAAGTNCDNETKYAFEKAGAKAEVIHINVLLSNKKILENYQLLALPGGFTYG 61
Query: 1125 DTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSN 1184
D + + K A I ++ L + +F D K LG+CNG Q++ G + S +
Sbjct: 62 DDVAAGKILANQIKYN--LEDEIKNFIDAKKLI-LGICNGFQVLVRAGLLP--SFERFHQ 116
Query: 1185 KAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSL 1244
+A L HN S +FE RW +KI + + + R +L + VAHGEG+F D +
Sbjct: 117 EAT--LTHNDSNKFEDRWVYLKICADTS---YFIRREHAPILYLPVAHGEGKFLAKDKDV 171
Query: 1245 LDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRW 1304
LDK+ KN Q+ QYVD++G+ YPMNPNGS +AG+ + G+ + MMPHPER V
Sbjct: 172 LDKIVKNRQIVFQYVDENGEDAG-YPMNPNGSVLNIAGICDQTGQILGMMPHPERNVDPT 230
Query: 1305 QCP 1307
Q P
Sbjct: 231 QHP 233
>UniRef50_O23992 Cluster: Expressed sequence tag; n=3; Eukaryota|Rep:
Expressed sequence tag - Hordeum vulgare (Barley)
Length = 127
Score = 132 bits (319), Expect = 6e-29
Identities = 66/127 (51%), Positives = 84/127 (66%), Gaps = 4/127 (3%)
Query: 1043 LEKRKGATYNVTFDPTAAVIKTKSI----KVAVLREEGINGDREMIASLMLANFDVFDVT 1098
L+ R ++++F P K S KVA++REEG N DREM A+ A F+ +D+T
Sbjct: 1 LKSRTSPLWHLSFTPKFTDKKLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDIT 60
Query: 1099 MSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFS 1158
MSDL N+K +L F+G+ F GGFSYAD L SAKGWAA I F++ L QF F +R DTFS
Sbjct: 61 MSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFS 120
Query: 1159 LGVCNGC 1165
LGVCNGC
Sbjct: 121 LGVCNGC 127
>UniRef50_Q98145 Cluster: Membrane antigen p140 homolog; n=310; Human
herpesvirus 8|Rep: Membrane antigen p140 homolog - Human
herpesvirus 8 (HHV-8) (Kaposi's sarcoma-associated
herpesvirus)
Length = 1308
Score = 132 bits (318), Expect = 8e-29
Identities = 153/619 (24%), Positives = 259/619 (41%), Gaps = 44/619 (7%)
Query: 729 GSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEXX 788
G A ++G Q K + + GA ++ EALTNL+F+ +S+L+DV +G W+ + +
Sbjct: 668 GQAMAMGEQAYKMATNVSTGATYAITEALTNLMFSPVSKLQDVVLTGAVAWSPEDH-QAG 726
Query: 789 XXXXXXXXXXXXMRALGVA--VDGGKDSLSMCA-HVAGEKVKSP------GTLVVSTYAP 839
R LGVA + S ++ HV + + ++V +++A
Sbjct: 727 LLQECLFACKEFCRELGVALSISSAASSPTLSERHVRITQQQETVEVLPFNSVVFTSWAE 786
Query: 840 CPDITVKIEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLF 899
D P K E +ALV+ V+ + GS + + SLF
Sbjct: 787 SRDPDTG-HPGRKVEGNALVYLAVNQSCL-IAGSTFEHNFLA-SRHPIPPLNPSTVASLF 843
Query: 900 KITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELG 959
+ + L+ ++ ++SGHDI +GG + + +EM + G RGL V++ A+ +P+E + +E LG
Sbjct: 844 MLVKYLMSKRLIVSGHDIGDGGLLPSAIEMALAGCRGLQ--VSLPAHPNPLELMVSETLG 901
Query: 960 IVLEVSKNDLPYVLSEYNNNGVGAQHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFRMW 1019
L + A +G G G + V + N V L + W
Sbjct: 902 HWLRCPRYTCQRCCGRPGYYRCVAHPLGTVGPEGQGNNVTVLQNETVVFQETLTSLQVSW 961
Query: 1020 EETSYRL-----ECLQANTDCVLQEWKVLEKRKGATYNVTFDPTAAVIK--TKSIKVAVL 1072
S + L D ++ LE G+ + + T ++A L
Sbjct: 962 TSFSDEMWNLVTPPLHPLEDMHRKDLGRLEHHLGSLRAMCLGSHLRLFSCPTSPRRMAAL 1021
Query: 1073 REEGINGDREMIASLMLANFDVFDVTMSDLQNKK-ITLDAFQGVVFPGGFSYADTLGSAK 1131
G + ++ +L +M ++K+ +L F G++ + SA+
Sbjct: 1022 VLPGSSAPYALMTALQNT---ALSASMGVEEHKRGQSLSGFSGLITCLRTGCQASYASAR 1078
Query: 1132 GWAAGILFSESLSSQFAHFKDRKDTFSLGVCN--GCQLMAMLGWVDPDSNSK---GSNKA 1186
GW + + +S F +R DTFS+ C G QL+ LG V +S G
Sbjct: 1079 GWVLALCNDPTCASTLTEFLNRPDTFSI-CCGEVGFQLLVALGVVGRSESSPYTYGPTPP 1137
Query: 1187 Q---IFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGS 1243
Q + L+ N S ++ W ++I +N + V+ R + G+VL W A GE +
Sbjct: 1138 QRWAVNLETNVSNLYDSHWLNIQI--PQNTKSVFLRVLRGTVLPSW-AQGEYLGVRYEQD 1194
Query: 1244 LLDK-LYKNGQVAVQY---VDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPER 1299
L+ L + G++ + Y D+ P YP NP G+ +AG+ S DGRH A++ P
Sbjct: 1195 ALEYILRQRGEITLTYHGNAADETLPARHYPRNPTGN-STVAGLTSSDGRHAALIIDPSL 1253
Query: 1300 CVLRWQCPAPCPTVTNPSV 1318
WQ A C T N V
Sbjct: 1254 MFHPWQV-AACSTRPNTPV 1271
Score = 47.6 bits (108), Expect = 0.002
Identities = 21/49 (42%), Positives = 31/49 (63%)
Query: 672 SALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAII 720
S + ++LR V SK + T +DRC GL+AQQ VGPL P++D ++
Sbjct: 568 STIHQLLRHSTVGSKEFFTRHMDRCSNGLIAQQAGVGPLDIPVSDYHLV 616
>UniRef50_Q6M0U0 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=4; Methanococcus|Rep:
Phosphoribosylformylglycinamidine synthase 1 -
Methanococcus maripaludis
Length = 272
Score = 128 bits (308), Expect = 1e-27
Identities = 82/233 (35%), Positives = 117/233 (50%), Gaps = 12/233 (5%)
Query: 1068 KVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTL 1127
KV V+ GIN + E + A + V ++DL K + ++ ++FPGGFSY D
Sbjct: 7 KVLVMSGYGINCETETAHAFQKAGAETDIVHINDLIAGKKKMADYEIIMFPGGFSYGDDT 66
Query: 1128 GSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQ 1187
GS +A I +L F + LG+CNG Q+M LG S G +
Sbjct: 67 GSGNAFANKI--KNNLFDDLTEFIN-SGKLILGICNGFQVMTNLGLFALPSTDYGERISA 123
Query: 1188 IFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDK 1247
L+ N++ R+ECRW +H EN + V G +V V +AHGEGRF D +
Sbjct: 124 --LESNTNNRYECRW----VHIKEN-DSVCVFTKGINVTHVPIAHGEGRF-YCDEKTYHE 175
Query: 1248 LYKNGQVAVQYVDDDGKPTE-VYPMNPNGSPDGLAGVRSRDGRHIAMMPHPER 1299
L +N Q+ Y D +G P YP+NPNG+ +AG+ + GR +MPHPER
Sbjct: 176 LKENKQIVFSYCDSEGNPANGEYPLNPNGAYQDIAGICDKTGRIFGLMPHPER 228
>UniRef50_Q97C36 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=4; Thermoplasmatales|Rep:
Phosphoribosylformylglycinamidine synthase 1 -
Thermoplasma volcanium
Length = 258
Score = 127 bits (306), Expect = 2e-27
Identities = 80/245 (32%), Positives = 129/245 (52%), Gaps = 22/245 (8%)
Query: 1065 KSIKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYA 1124
+S K+ +L EG N + E+ S+ + + ++DL + + + G++ PGGFS
Sbjct: 3 QSPKIGILLMEGTNNETEVYYSVKRSGGSPDFIHINDLSAGRKRVSDYDGLIIPGGFSAG 62
Query: 1125 DTLGSAKGWAAGILFSESLSS----QFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNS 1180
D + AG++F+ L + + F D +G+CNG Q++ +G +
Sbjct: 63 DYI------RAGVIFAARLGAVAGKEIREFVDDGKPL-IGICNGFQVLMEMGLI------ 109
Query: 1181 KGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVA 1240
++++I L +N S RFECR++ +K+ F G G V V VAH EGR V+
Sbjct: 110 --YDRSKITLTNNESNRFECRYTYMKMTSRNRIFQSGFYGKG--VFQVPVAHAEGRIAVS 165
Query: 1241 DGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERC 1300
+ S+L KLY+N QV +Y ++ T+ YP NPNGS D +A + + G I +MPHPER
Sbjct: 166 ERSVLKKLYENDQVVFKY-SNENDVTDEYPWNPNGSIDSVASLSNEAGNVIGLMPHPERI 224
Query: 1301 VLRWQ 1305
R+Q
Sbjct: 225 YYRYQ 229
>UniRef50_A5UUD1 Cluster: Phosphoribosylformylglycinamidine synthase
I; n=5; Chloroflexi (class)|Rep:
Phosphoribosylformylglycinamidine synthase I -
Roseiflexus sp. RS-1
Length = 268
Score = 126 bits (304), Expect = 4e-27
Identities = 87/247 (35%), Positives = 128/247 (51%), Gaps = 12/247 (4%)
Query: 1065 KSIKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYA 1124
K+ +V +LR GIN D + ++ LA V ++ L + L + +V PGGFSY
Sbjct: 3 KTPRVLILRAAGINRDSDAATAIELAGGRPEVVHINRLISGDRRLMDYAMLVVPGGFSYG 62
Query: 1125 DTLGSAKGWAAGILFSESLSSQFAHF-KDRKDTFSLGVCNGCQLMAMLGWVD--PDSNSK 1181
D LG+ K A ++ L Q F D + +G+CNG Q + G + P + +
Sbjct: 63 DHLGAGKLLAVDLI--HCLGDQITRFIADGRPV--IGICNGFQALVKAGILPGTPLTEAS 118
Query: 1182 GSNKAQ-IFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVA 1240
+ AQ + L N+S RFECRW V++ + V+ R + + V VAHGEGRF
Sbjct: 119 TPSPAQSVTLTDNASGRFECRW--VRLAADPGSVCVFTRSIDRPI-EVPVAHGEGRFVTR 175
Query: 1241 DGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERC 1300
+ + L L G VA++YV +G P YP NPNGS D +AG+ + G + +MPHPE
Sbjct: 176 NAAALAALRAAGLVALRYVAANGSPPS-YPENPNGSEDNIAGICNPGGNVLGLMPHPENA 234
Query: 1301 VLRWQCP 1307
V +Q P
Sbjct: 235 VFPYQHP 241
>UniRef50_Q2FPM9 Cluster: Phosphoribosylformylglycinamidine synthase
I; n=3; Methanomicrobiales|Rep:
Phosphoribosylformylglycinamidine synthase I -
Methanospirillum hungatei (strain JF-1 / DSM 864)
Length = 282
Score = 124 bits (298), Expect = 2e-26
Identities = 81/235 (34%), Positives = 124/235 (52%), Gaps = 14/235 (5%)
Query: 1068 KVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTL 1127
K ++ GIN + E L+ A D + ++DL ++K + ++ +VFPGGFSY D
Sbjct: 21 KALIMSGYGINSEIETREVLLRAGMDADIIHINDLIDRKYRMCDYRLLVFPGGFSYGDDT 80
Query: 1128 GSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQ 1187
G+ +A + +L + F + +D LG+CNG Q++A LG V P N + K
Sbjct: 81 GAGNAYANRV--RNNLWNDVTEFLE-EDNLVLGICNGFQILANLGLV-PAFNKQ--YKRD 134
Query: 1188 IFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDK 1247
I L N ECR+ +K E +W +G+ V V +HGEG F+ + +L +
Sbjct: 135 IALMPNRKGVLECRYVTIK----PASETLWTKGIERIVCPV--SHGEGNFSCSK-EVLTE 187
Query: 1248 LYKNGQVAVQYVDDDGKPTE-VYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCV 1301
L +A Y ++ KP + YP NPNGS +AG+ S DG+ +AMMPHPER +
Sbjct: 188 LRSQKMIAFTYCRENLKPADGEYPYNPNGSVADIAGITSADGKVLAMMPHPERAM 242
>UniRef50_A5UWJ5 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=5; Chloroflexi (class)|Rep:
Phosphoribosylformylglycinamidine synthase II -
Roseiflexus sp. RS-1
Length = 985
Score = 121 bits (291), Expect = 2e-25
Identities = 184/801 (22%), Positives = 296/801 (36%), Gaps = 68/801 (8%)
Query: 171 PKDLEPWFV-VPLQEQGISAMRKVNDKLGLAFDTWDMEFYMDLFVNKLKRDPTSVELFDL 229
P D EP +P+ + +++ L+ D +M + + R+PT EL L
Sbjct: 149 PADHEPLVAHIPITTASDEELMRISQAGVLSLDLEEMRA-IQAYYRAEGREPTDGELETL 207
Query: 230 AQSNSEHSRHWFFKGKLVLDGKEINESLIDMVASTQKTSNNNNVIKFGDNSSAIKGF--- 286
AQ+ SEH H FKG++ ++ + D+ + + + + + + S I+ F
Sbjct: 208 AQTWSEHCSHKTFKGRVRYQN-QVPLNPQDVALPAEHYPSLHLLSRDCEIDSLIRTFLMA 266
Query: 287 -QHTILRPTNVRG---------PSQVIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGG 336
+L R + ++ +I F ETHN P+A+ PF GA TG GG
Sbjct: 267 ATRRVLDQRRDRDFAVISAFVDNAGIVAFDEHYEISFKVETHNHPSALEPFGGANTGVGG 326
Query: 337 RIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGA 396
+RDV GV +A T + G L +P +L G +P A + G
Sbjct: 327 VVRDVLGV--SAQPIANTDVFCFGPLDLPTTEL---SPGVLHPQRIAAGVVA------GV 375
Query: 397 SDYGNKFGEPVISGFVQSYGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKN-KPDKGML 455
DYGNK G P ++G V Y R P+++ G +G P + +P ++
Sbjct: 376 RDYGNKLGIPTVNGAV-FY-------DRGYVANPLVYCGTVGLAPRDTHPRAVRPGDAIV 427
Query: 456 LVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLESD 515
++ + AVQ GD ++ VV D
Sbjct: 428 VIGGRTGRDGIHGATFSSAELTHTTAEEVG-----SAVQIGDPITEKKMIDVV--LQARD 480
Query: 516 VNPVESIHDQGAGGNGNVLKELVEPEGAVVFTKEFQLGDPTITTLELWGAEYQENDALLC 575
+I D GAGG + + E+ GA V L + E+W +E QE L
Sbjct: 481 RGLYSAITDCGAGGLSSAVGEMGADCGAEVELARAPLKYAGLQPWEIWLSEAQERMVLAV 540
Query: 576 SKANRHILEEICRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYD 635
L +C E + +G T G L+ +D + E + + +
Sbjct: 541 PPQCLERLLALCASEDVEATVIGRYTDTG--RLVVRYNGASVVDLAMSFLHEGRPQRVLE 598
Query: 636 LHLEAVLGNMPRKTFDLQTEKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDR 695
+ G++P+ + + + + V L +L N+ASK + D
Sbjct: 599 ARWDG--GSLPKPQMTVHNGDQDR--------VDVAHLLLALLAHPNIASKAPIVRTYDH 648
Query: 696 CVTGLVAQQQCVGPLHTPLADCAIIALSYYDLVGSATSIGTQNIKGLLDPAAGARLSLGE 755
V G + VG D A++ + G A G GL+DP A + E
Sbjct: 649 EVGGRTVVKPLVGAACDGPGDAAVLQPLPSSVRGIAIGCGINPRYGLIDPYWMALACVDE 708
Query: 756 ALTNLVFAGISELEDVKCSGNWMWAG-KTGVEXXXXXXXXXXXXXXMRALGVAVDGGKDS 814
AL N+V G ++ N+ W + A G GKDS
Sbjct: 709 ALRNVVAVG-ADPTRAAILDNFCWGDPRLPDRMAGLVRAAAGCYDAAVAYGAPFISGKDS 767
Query: 815 L-SMCAHVAGEKVKSPGTLVVSTYAPCPDITVKIEPALKEENSALVHAPVSPGKYRLGGS 873
L + G + P TL++S A PDI + KE +A+ ++ + LGGS
Sbjct: 768 LNNEYRDAEGRRTPIPPTLLISALALVPDIRRAVTSDFKEPGNAVYLVGLT--RAELGGS 825
Query: 874 AL-----AQCYK-QLGDNXXXXXXXXXXKS--LFKITQKLLKEKKLISGHDISEGGFITT 925
L A C L D ++ L + + + HD+SEGG
Sbjct: 826 HLLDALPASCISPALSDALTQMPRVDLAQAPQLMAALHAAISAGLVRACHDLSEGGLGVA 885
Query: 926 VLEMGIGGVRGLNLHVNVAAN 946
V EM + G G+ L V ++
Sbjct: 886 VAEMALAGNLGVTLDVRAVSH 906
>UniRef50_O41976 Cluster: Tegument protein/FGARATc; n=1; Murid
herpesvirus 4|Rep: Tegument protein/FGARATc - Murid
herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68)
Length = 1310
Score = 118 bits (284), Expect = 1e-24
Identities = 140/632 (22%), Positives = 245/632 (38%), Gaps = 45/632 (7%)
Query: 732 TSIGTQNIKGLLDPAAGARLSLGEALTNLVFAG-ISELEDVKCSGNWMWAGKTGVEXXXX 790
T +G Q K +DP GA L EA+ N++ + + + +G+ W+
Sbjct: 695 TGVGEQYYKMQVDPVRGAVYGLVEAILNMLTSNCVHGWRKMAITGSISWSSDDP-SYSLL 753
Query: 791 XXXXXXXXXXMRALGVAVDGGKDSLSMCAHVAGEKVKSPGTLVVSTYAPCPDITV---KI 847
+L + + ++ S G + P T ++ A CP + K
Sbjct: 754 YQTLMACKDFCYSLSIPITY-TNATSGQTQDTGPR-PGPTTNSIAFTAQCPGVMGTYRKT 811
Query: 848 EPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLK 907
P K S ++ P+S K L G+ Q K L N +L + L
Sbjct: 812 TPDFKSHGSYIIWLPMSQ-KLTLAGTIFQQISK-LKANKLHKLAPEYISNLAHALEMLTS 869
Query: 908 EKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGIVLEVSKN 967
++S HD+S+GG I +LEM + G +G N+ + + P + L +E G+V+EV K
Sbjct: 870 RTAILSMHDVSDGGLIAAILEMAMAGNKGCNIEM-PSYITRPFDMLISETPGMVIEVEKK 928
Query: 968 DLPYVLSEYNNNGVGAQHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFRMWEETSYRLE 1027
+ V + + +G K+G + V I+ G + L V R W T
Sbjct: 929 SMEMVKAILKFKSLTYYKLGQVAKHGEEPVVEISHAGKQLFKAHLSTVMRWWRHTYSSHI 988
Query: 1028 CLQANTDCVLQEWKVLEKRKGATYNVTFDPTAAVIKTKSIK---------VAVLREEGIN 1078
Q + ++ VL+ T P + +K V V G
Sbjct: 989 TQQCSNLSAKEKLYVLDYGNNKTDLGLMGPGMRSRHLRPVKCVDPDFGAYVCVACSPGQP 1048
Query: 1079 GDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGIL 1138
++++L + FD V + L+ L+ + G++F G + +A A ++
Sbjct: 1049 PPHSLMSALSNSGFD--PVPCNILELAHTDLNEYSGIIFSGHSGAEKNVTAASILANSLV 1106
Query: 1139 FSESLSSQFAHFKDRKDTFSLGVCN-GCQLMAMLGWVDPDSNS----KGSNKAQIF---- 1189
++ + F ++ TF LG G QL+ L V+ D ++ + + ++F
Sbjct: 1107 TNQDFTETLTRFYNKSHTFILGFGELGTQLLLALDIVNLDQSNPQFISRTEERELFQHGA 1166
Query: 1190 LDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLY 1249
L+ N+S EC W + ++ + V+ + GSV+ W +L
Sbjct: 1167 LEPNASALLECLWLNFYVRQSRS---VFLAPISGSVVPAWAVGTHLGINFNHDGAEQRLM 1223
Query: 1250 KNGQV-AVQYVDDDGKPTEV--YPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQC 1306
+GQ+ A + + G+ E YP NP+G+ +A S DGR AM+ P + WQ
Sbjct: 1224 TSGQISATFHGPEPGRNLEAAHYPRNPSGA-SNVAAFCSPDGRATAMLIDPSQSFFPWQ- 1281
Query: 1307 PAPCPTVTNPSVRNSQASPWLRLFQNAYSWAI 1338
N Q +PW F W++
Sbjct: 1282 -------WQYDAENLQCTPWQICFFRLLLWSL 1306
>UniRef50_A6PUZ9 Cluster: Phosphoribosylformylglycinamidine synthase;
n=1; Victivallis vadensis ATCC BAA-548|Rep:
Phosphoribosylformylglycinamidine synthase - Victivallis
vadensis ATCC BAA-548
Length = 268
Score = 118 bits (284), Expect = 1e-24
Identities = 90/276 (32%), Positives = 137/276 (49%), Gaps = 14/276 (5%)
Query: 1062 IKTKSIKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGF 1121
+K IKV V+ G+N +RE A+ L V ++DL + L+ +Q +VF GGF
Sbjct: 1 MKKSDIKVLVITGFGLNCERETAAACKLVGAAPEQVHLNDLIAGRHKLEEYQFLVFIGGF 60
Query: 1122 SYADTLGSAKGWAAGILFSESLSSQFAHF-KDRKDTFSLGVCNGCQLMAMLGWVDPDSNS 1180
S+ D LGS +A + F L Q F D K +G+CNG Q + LG V P N
Sbjct: 61 SFGDHLGSGTVFANRVKFR--LHDQLEKFVADGK--LVMGICNGFQTLTRLGMV-PALNG 115
Query: 1181 KGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVA 1240
++ + L HN S F W +K + V+ R M + + + HGEG+F VA
Sbjct: 116 DYFSQT-VALAHNDSGVFRDDWCTLKA--DPASPCVFTRNM--ETVRLPLRHGEGKF-VA 169
Query: 1241 DGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERC 1300
D ++L ++ AV+YV+DDG +P NPNGS + +AGV GR +MPHPE
Sbjct: 170 DPAVLAEIEAKHLAAVRYVNDDGTLATEFPANPNGSLNSIAGVCDPTGRIFGLMPHPEAF 229
Query: 1301 VLRWQCPAPCPTVTNPSVRNSQASPWLRLFQNAYSW 1336
+ + +P T + + ++ + F+NA +
Sbjct: 230 LSPYN--SPTWTADKAAGKVAEEGDGVAFFRNAVDY 263
>UniRef50_Q3Z9H5 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=3; Dehalococcoides|Rep:
Phosphoribosylformylglycinamidine synthase 1 -
Dehalococcoides ethenogenes (strain 195)
Length = 255
Score = 118 bits (284), Expect = 1e-24
Identities = 89/271 (32%), Positives = 127/271 (46%), Gaps = 22/271 (8%)
Query: 1067 IKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADT 1126
+K +LR G N D E + LA + V +++L K L FQ + FPGGF Y D
Sbjct: 4 VKTLILRTPGTNCDIETSYAFELAGSETEMVHINELLAKPSRLAEFQIMAFPGGFGYGDD 63
Query: 1127 LGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKA 1186
LG+ + A + L + F + +G+CNG Q + G + P G
Sbjct: 64 LGAGRVLANEVRLK--LGEKINRFHESGGLI-IGICNGFQALVKTG-ILPGPMKDGQ--- 116
Query: 1187 QIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLD 1246
+I L N+S RFECRW+ + + N V+ +G+ L V AHGEG+ + +++
Sbjct: 117 KITLTENNSGRFECRWTYLAV--NPFSTCVFTQGIDRLYLPV--AHGEGKL-LGSPEVIN 171
Query: 1247 KLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQC 1306
KL V Y D DGK YP NP G+ +AG+ GR A+MPHPER V Q
Sbjct: 172 KLNS----VVYYTDKDGKRNSPYPANPAGTLMDIAGIADESGRIFALMPHPERFVRGSQH 227
Query: 1307 PAPCPTVTNPSVRNSQASPWLRLFQNAYSWA 1337
P P+ + L++F NA WA
Sbjct: 228 P------RWPAEGLKEEGDGLKIFTNAVKWA 252
>UniRef50_A6G365 Cluster: Phosphoribosylformylglycinamidine synthase;
n=1; Plesiocystis pacifica SIR-1|Rep:
Phosphoribosylformylglycinamidine synthase - Plesiocystis
pacifica SIR-1
Length = 303
Score = 113 bits (271), Expect = 4e-23
Identities = 77/238 (32%), Positives = 120/238 (50%), Gaps = 12/238 (5%)
Query: 1065 KSIKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYA 1124
++++V V G+N + E A+ L V V +SDL + L +VF GGFS+
Sbjct: 33 EAVRVLVPTGYGLNCEAESAAAFELLGAQVEQVHVSDLLAEPGRLSQASILVFIGGFSFG 92
Query: 1125 DTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSN 1184
D + S + +A + F L + A F ++G+CNG Q+M LG + P + + S
Sbjct: 93 DHVASGRVFANRMRFG--LGRELARFI-ADGGLAVGMCNGFQVMTKLGLL-PGALGEASP 148
Query: 1185 KA----QIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVA 1240
+A Q+ + N + W V++ + VW RG+ + HGEG+ A
Sbjct: 149 EALAPQQVSIVGNDRLGYRNAW--VRMRVDPESPCVWTRGVES--IESPSRHGEGKLVFA 204
Query: 1241 DGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPE 1298
++ D+L+ +V V+YVD G+ T +P NPNGSPDG AG+ GR +MPHPE
Sbjct: 205 SDAVRDQLFAERRVPVRYVDAQGEATSEWPANPNGSPDGAAGLCDASGRVFGLMPHPE 262
>UniRef50_Q5FDA5 Cluster: Phosphoribosylformylglycinamidine synthase;
n=12; Rickettsiales|Rep:
Phosphoribosylformylglycinamidine synthase - Ehrlichia
ruminantium (strain Welgevonden)
Length = 277
Score = 112 bits (269), Expect = 7e-23
Identities = 79/242 (32%), Positives = 124/242 (51%), Gaps = 26/242 (10%)
Query: 1067 IKVAVLREEGINGDREMI------ASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGG 1120
+ V VL G+N + E + L+ N V + ++++ + L + +V PGG
Sbjct: 13 MNVIVLSGYGLNCEEETVFAFLKAGELLSCNVQVKVMHINEVVSNPRLLKGYNVLVIPGG 72
Query: 1121 FSYADTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNS 1180
FSY D G+ +A +L + + F D LG+CNGCQ++ +
Sbjct: 73 FSYGDYTGAGNAFALRML--NNFKEEIEEFLTA-DKLVLGICNGCQVLIRVI-------- 121
Query: 1181 KGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVA 1240
S+ + I L NS ++++CRW VK+ N+ + VW + L + VAHGEGRF +
Sbjct: 122 --SDFSCITLLSNSVKQYQCRWVKVKV--NQLNDSVWLYEL--DELYIPVAHGEGRFFLE 175
Query: 1241 DGSLLDKLYKNGQVAVQYVDDDGK-PTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPER 1299
S+ D K+ ++A+QYV D G + +P NPNGS +A + S +GR + MMPHPER
Sbjct: 176 SNSI-DVSIKD-KIALQYVTDKGNLANQQFPYNPNGSVYDIAALSSNNGRVLVMMPHPER 233
Query: 1300 CV 1301
V
Sbjct: 234 AV 235
>UniRef50_Q2Q0E4 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=1; uncultured organism HF10_3D09|Rep:
Phosphoribosylformylglycinamidine synthase II -
uncultured organism HF10_3D09
Length = 1008
Score = 111 bits (267), Expect = 1e-22
Identities = 168/771 (21%), Positives = 289/771 (37%), Gaps = 74/771 (9%)
Query: 221 PTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINE-SLIDMVASTQKTSNNNNVIKFGDN 279
PT VEL LAQ+ SEH +H F K+ E NE ++ID + T +++ K D
Sbjct: 241 PTDVELECLAQTWSEHCKHKIFASKIHHIDTETNEDTVIDSIFKTHIMKPTHDMAKEVDW 300
Query: 280 SSAIKGFQHTILRPTNVRGPSQVIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIR 339
++ S VI + I AETHN P+A+ P+ GA TG G R
Sbjct: 301 LLSV------------FHDNSGVIAWNDDWSICMKAETHNSPSALDPYGGAMTGIVGVNR 348
Query: 340 DVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDY 399
D+ G G G +A T + G WE + PS P +++ G
Sbjct: 349 DILGTGLGARPIANTDVFCFG-------PPDWE---GDLPSTLFHPSRVLRGVHAGVRVG 398
Query: 400 GNKFGEPVISGFVQSYGLKNADNTREEFV-KPIMFSGGIGYMPHSMIKKNKPDKGMLLVK 458
GN+ G P I+G + E ++ KP+++ G +G MP + + +
Sbjct: 399 GNESGIPTINGSIV---------FDERYIGKPLVYCGTVGLMPRRLADGRESHEKNPTPG 449
Query: 459 XXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLESDVNP 518
+ D + AVQ GD ++ ++ +S +
Sbjct: 450 DLVYMVGGRVGSDGIHGATFSSLELTDES-PSSAVQIGDPITQKKMMDMLLEARDSCL-- 506
Query: 519 VESIHDQGAGGNGNVLKELVE-PEGAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSK 577
+ D GAGG + + E+ E G + + L +++ E+ +E QE + +
Sbjct: 507 ITCTTDNGAGGLSSSIGEMAEYTNGCEIDLGKVPLKQEGLSSWEILVSESQERMTVAVAP 566
Query: 578 ANRHILEEICRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLH 637
++ E + + V T GY + T +L
Sbjct: 567 KDKSAFEALAELHEVEATQVATFTNTGYFHVKHGDETVAYLP------------------ 608
Query: 638 LEAVLGNMPRKTFDLQTEKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCV 697
+E + +P+ + + + P D+ L+ +L N+ASK + D V
Sbjct: 609 IEFLHDGVPQLELESEWVPPQHVTFVPPSDLDHNVLLNEMLARPNIASKETWVRQYDHEV 668
Query: 698 TGLVAQQQCVGPLHTPLADCAIIALSYYDLVGSATSIGTQNIKGLLDPAAGARLSLGEAL 757
+ VG D +IA + + G S G +D A S+ EA+
Sbjct: 669 IAQTVVKPFVGVERDGPGDAGLIAPIHGNPQGLVVSCGIAPRYSDIDAGAMVAASIDEAV 728
Query: 758 TNLVFAGISELEDVKCSGNWMW-----AGKT---GVEXXXXXXXXXXXXXXMRALGVAVD 809
N V G+ +++ + N+ W + KT + RA +
Sbjct: 729 RNAVCVGV-DIDKMAGLDNFCWPDPIESEKTPDGKFKLAQLVRANRELERVCRAYRLPCV 787
Query: 810 GGKDSLSMCAHVAGEKVKSPGTLVVSTYAPCPDITVKIEPALKEENSALVHAPVSPGKYR 869
GKDS+ V K+ P T++ S + PD+ K + V
Sbjct: 788 SGKDSMKNDYGVWPNKISIPPTMLFSLFGNQPDVRKTATSNFKRHGERIY--LVGTTYEE 845
Query: 870 LGGSALAQCYKQLGDNXXXXXXXXXXKS---LFKITQKL---LKEKKLISGHDISEGGFI 923
LG S +A ++ GD + ++ +KL ++ + + HD SEGG
Sbjct: 846 LGASEVAFHLRERGDATGIGGQVPRLEDPVRQLEVYRKLSSSIQNGLIRTAHDCSEGGLA 905
Query: 924 TTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELG-IVLEV-SKNDLPYV 972
+ EM IGG G + ++ + L++E LG I++ V ++++L +V
Sbjct: 906 VALAEMCIGGRCGAIIDIDGIGSCDVFSRLWSESLGRIIVSVEAEHELAFV 956
>UniRef50_Q73MV2 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=1; Treponema denticola|Rep:
Phosphoribosylformylglycinamidine synthase 1 - Treponema
denticola
Length = 270
Score = 111 bits (267), Expect = 1e-22
Identities = 79/248 (31%), Positives = 125/248 (50%), Gaps = 22/248 (8%)
Query: 1068 KVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTL 1127
+ VL G N D + +L LA + V ++ L+ K+ ++ +V PGGFSYAD L
Sbjct: 4 RALVLHATGTNRDGDAARALELAGAEPEIVHINKLKAKEKNWKDYEILVIPGGFSYADAL 63
Query: 1128 GSAKGWAAGI--LFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWV---DPDS---- 1178
G+ K +A + F + +S A K +G+CNG Q++ G + + D
Sbjct: 64 GAGKLFALDLSNYFFDEVSEFVAAGKP-----VIGICNGFQVLVKSGILPGKEKDGKVIL 118
Query: 1179 NSKGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFT 1238
+ G Q L +N RFECR++ + I + N +W + + G++ +AHGEGRF
Sbjct: 119 DKDGYKNRQATLTYNKQGRFECRFTTM-IPQKSN--CIWTKDLKGNI-HCPIAHGEGRFL 174
Query: 1239 VADGSLLDKLYKNGQVAVQYVDDDGKPT----EVYPMNPNGSPDGLAGVRSRDGRHIAMM 1294
LD L++ GQ+A+ Y D + + YP NPNGS +AG+ + G + +M
Sbjct: 175 TDSQKTLDDLFEKGQIALVYGGKDAEKSIPANGEYPFNPNGSLADIAGICNTKGNVLGLM 234
Query: 1295 PHPERCVL 1302
PHPE V+
Sbjct: 235 PHPENNVV 242
>UniRef50_Q1FHW3 Cluster: Phosphoribosylformylglycinamidine synthase;
n=3; Clostridiales|Rep: Phosphoribosylformylglycinamidine
synthase - Clostridium phytofermentans ISDg
Length = 1293
Score = 110 bits (264), Expect = 3e-22
Identities = 117/416 (28%), Positives = 182/416 (43%), Gaps = 44/416 (10%)
Query: 898 LFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEE 957
L++ KL+ EK ++S + + G +V +M G G++ N+ + LF
Sbjct: 882 LYQAITKLIHEKVIVSAYALGAKGIAESVSKMAFGNQLGVDFDPNLTDS-----DLFAPA 936
Query: 958 LG-IVLEVSKNDLPYVLSEYNNNGVGAQHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVF 1016
G IV EVS++D +V + N V Q +G D+++ N +++ + +
Sbjct: 937 YGDIVAEVSESD--FVKLDALN--VSYQMVGTV----TDTRI-FNYKDISI---TMEEAL 984
Query: 1017 RMWEETSYRLECLQANTDCVLQEWKVLEKRKGATYNVTFDP-TAAVIKTKSIKVAVLRE- 1074
W T ++ ++N + + +E K Y FD T + K K K V
Sbjct: 985 SAWSNTLEKVFPTRSNME------EEVETEKVPCY--LFDAKTIYIAKNKVAKPKVFIPV 1036
Query: 1075 -EGINGDREMIASLMLANFDVFDVTMSDLQNKKI--TLDAFQGVV-------FPGGFSYA 1124
G N + + + + A +V V +L + I ++DAF+ + FPGGFS
Sbjct: 1037 FPGTNCEYDSLRAFERAGAEVKTVVFKNLDERSIIESVDAFEKAIKEAQILMFPGGFSAG 1096
Query: 1125 DTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSN 1184
D + + A + +S KD LG+CNG Q + LG V P+
Sbjct: 1097 DEPDGSGKFIATAFRNVRISDAVNDLLKIKDGLVLGICNGFQALIKLGLV-PNGEIMPQT 1155
Query: 1185 KAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMG-GSVLGVWVAHGEGRFTVADGS 1243
L N+ R + K+ N++ W R G V + +HGEGRF VA+
Sbjct: 1156 VDSPTLTMNNIGRHISKTVYTKVVSNQSP---WLRKAELGGVYSIPASHGEGRF-VANEE 1211
Query: 1244 LLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPER 1299
L KL NGQ+A QYVD +G PT NPNGS + G+ S DGR + M H ER
Sbjct: 1212 WLKKLAANGQIATQYVDMNGNPTMDENYNPNGSYYAIEGITSPDGRVLGKMAHSER 1267
Score = 47.6 bits (108), Expect = 0.002
Identities = 85/389 (21%), Positives = 142/389 (36%), Gaps = 46/389 (11%)
Query: 171 PKDLEPWFVVPLQEQGISAMRKVNDKLGLAFDTWDMEFYMDLFVNKLKRDPTSVELFDLA 230
P+D+ +++ Q G + + + + L LA D + + F + KRDP+ E+ L
Sbjct: 163 PEDIS--YLIGFQSMGETKLLLLYESLNLAMTYADFKHIQNYFKVEEKRDPSITEIRVLD 220
Query: 231 QSNSEHSRHWFFKGKLVLDGKEINESLIDMVASTQKTSNNNNVIKFGDNSSAIKGFQHTI 290
S+H RH F +L E + A+ + N ++ + I +
Sbjct: 221 TYWSDHCRHTTFLTELTKVDFEEGYYKEPIKAAYEDYKANREILYKDRDDKYISLMDIAL 280
Query: 291 LRPTNVRGPSQVIQKKTESDI--------------------IFTAETHNMPTAVAPFSGA 330
L ++ ++ + +I F ETHN PT + PF GA
Sbjct: 281 LAMKKLKADGKLEDMEVSDEINACSIVVPVEIDGVTEEWLVFFKNETHNHPTEIEPFGGA 340
Query: 331 TTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIII 390
T GG IRD GRG A V P L +G + P +I+
Sbjct: 341 ATCLGGAIRDPLS-GRGYVYQA----MRVTGAADPTVSLKDTLQG-KLPQR-----KIVT 389
Query: 391 EASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKNKP 450
A+ G S YGN+ G + +G V N R E + +M G P + +
Sbjct: 390 GAAKGYSSYGNQIG--LATGLVDEIYHPNYVAKRME-IGAVM-----GAAPRKNVIRENS 441
Query: 451 DKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRG 510
+ G +++ + + VQ+G+A +L R+ R
Sbjct: 442 EPGDIIILMGGRTGRDGCGGATGSSKVHTTESIQTCGAE---VQKGNAPTERKLQRLFR- 497
Query: 511 CLESDVNPVESIHDQGAGGNGNVLKELVE 539
E ++ +D GAGG + EL +
Sbjct: 498 -REEVSKLIKKCNDFGAGGVSVAIGELAD 525
>UniRef50_P11282 Cluster: Probable membrane antigen 75; n=3;
Herpesviridae|Rep: Probable membrane antigen 75 -
Saimiriine herpesvirus 2 (strain 11) (SaHV-2)
(Herpesvirus saimiri)
Length = 1299
Score = 109 bits (263), Expect = 4e-22
Identities = 144/625 (23%), Positives = 252/625 (40%), Gaps = 51/625 (8%)
Query: 733 SIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEXXXXXX 792
++G Q K +P G + ++ EA+TN++F LED+ + W + E
Sbjct: 705 ALGEQAYKLSRNPIVGVKYAIAEAITNIMFGPDCVLEDITLTVAAHWNKQ---ETAALYR 761
Query: 793 XXXXXXXXMRALGVAVDGGKDSLSMCAHVAGEKVKSPGTLVVSTYAPCPDITVKIEPALK 852
R L V + S S + + + T+VV+ A I +I PALK
Sbjct: 762 VLFACKEMCRELNVNLSITDASDSRDTPI--QDTDAANTVVVTASARVTSIE-RITPALK 818
Query: 853 EENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLKEKKLI 912
+ +ALVH +S + L GS + + + +F + L+ + ++
Sbjct: 819 KAENALVHVCLSK-ELTLSGSVFENSFTAFSSHLPDLDTSKL-RDMFYAVKHLISKNLVV 876
Query: 913 SGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGIVLEVSKNDLPYV 972
+GHDIS+GG ITT EM G+ VN+ + + + L +E G +LEV K L V
Sbjct: 877 AGHDISDGGLITTAAEMCFASTFGVT--VNLPSALPALMYLVSETPGALLEVPKEHLSTV 934
Query: 973 LSEYNNNGVGAQHIGYTGKYGMDSQVVINLNGVNVLD---TVLIDVFRMWEETSYRLECL 1029
+ + G+ +G + I NG ++L +L + + E S+ E
Sbjct: 935 TTLLSERGLTWYAVGTVNNV---KNLSIYDNGTHLLTESINILNSKWMSYAEESF--ETC 989
Query: 1030 QANTDCVLQE--WKVLEKRKGATYNVTFDPTAA-VIKTKSIKVAVLREEGINGDREMIAS 1086
+ + + + + K T P + + VAVL G + +
Sbjct: 990 EPHIESMYRNDYGNNAMDLKHLEDLCTHKPLQLYTCPSHPVSVAVLTFPGCPDPVATLQA 1049
Query: 1087 LMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQ 1146
F + ++ L L+AF + G ++ + + +L + +
Sbjct: 1050 FANVGFLSYPISTEFLLQGN-NLNAFSCLAVSGSSAFEEEGTGTRIAIYTLLQCDLAKNC 1108
Query: 1147 FAHFKDRKDTFSLGVCN--GCQLMA---MLGWVDPDSNSKGSNKAQ--IFLDHNSSERFE 1199
F R DT SL C G QL+A ++G P SN + L+ N+S+ +E
Sbjct: 1109 LKEFFQRPDTLSL-CCGELGTQLLAACQVVGDTHPSRGDISSNPESWTLELEPNASKHYE 1167
Query: 1200 CRWSAVKIHENENKEDVWFRGMGGSVL--GVWVAHGEGRFTVADGSLLDKLYKNGQVAVQ 1257
W + H + + + + + G++ G+W G A ++ +NG +A+
Sbjct: 1168 SLW--LNFHVPQTTKSIILQALRGTIFQDGLWQVLGLRYKHDAQEYIMQ---QNGTIAMS 1222
Query: 1258 YVDDDGKP---TEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCP-APCPTV 1313
Y P YP NP+G+ +AG+ S++GRH+A++ P WQ P P V
Sbjct: 1223 YHSAKINPYLYAMHYPRNPSGN-SSVAGICSKNGRHLALLVEPALSFHTWQWQHIPKPLV 1281
Query: 1314 TNPSVRNSQASPWLRLFQNAYSWAI 1338
T SPW ++Q + W +
Sbjct: 1282 T---------SPWALMYQCMFLWCV 1297
Score = 44.8 bits (101), Expect = 0.016
Identities = 21/49 (42%), Positives = 30/49 (61%)
Query: 672 SALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAII 720
S + +L VASK + ++DRC GL+AQQ +GP P++D AII
Sbjct: 605 STISNILSHPAVASKSNIIRRLDRCGNGLIAQQPGIGPSDAPVSDYAII 653
>UniRef50_Q59042 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=14; cellular organisms|Rep:
Phosphoribosylformylglycinamidine synthase 1 -
Methanococcus jannaschii
Length = 230
Score = 109 bits (261), Expect = 7e-22
Identities = 77/233 (33%), Positives = 120/233 (51%), Gaps = 28/233 (12%)
Query: 1067 IKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADT 1126
+K+AV + G N D ++ ++ LA + ++ +N LD+++G V PGGFSY D
Sbjct: 1 MKIAVTKFLGTNCDLDVCHAVKLAGGEP-ELVFFTQEN----LDSYKGAVIPGGFSYGDY 55
Query: 1127 LGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKA 1186
L A +A + L K LG+CNG Q+ G+ SKG+
Sbjct: 56 L-RAGAISARTPIIKGLKKMVEEGKP-----VLGICNGAQIGLEAGF------SKGT--- 100
Query: 1187 QIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLD 1246
L +N + +F C+W +++ N+ +++ G VL + +AH EGRF AD LD
Sbjct: 101 ---LTNNLNAKFICKWVYIRVENNKTPFTQYYKK--GEVLKIPIAHAEGRF-YADDETLD 154
Query: 1247 KLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPER 1299
+YKN + +Y D+ G+ TE NPNGS D +AGV + + + +MPHPER
Sbjct: 155 YMYKNNMIVFKYCDETGEVTE--EANPNGSIDNIAGVCNENQNCVLLMPHPER 205
>UniRef50_Q2VSN3 Cluster: ORF3; n=3; Rhadinovirus|Rep: ORF3 - Ovine
herpesvirus 2
Length = 1361
Score = 106 bits (255), Expect = 4e-21
Identities = 145/620 (23%), Positives = 238/620 (38%), Gaps = 44/620 (7%)
Query: 729 GSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAG-KTGVEX 787
G+ +G + +P GA L++ E+LTNLV IS D + G G
Sbjct: 720 GTCVGLGEKTCFTQANPPLGALLAITESLTNLVLGPISNFNDTTVG---LTVGIPQGYRF 776
Query: 788 XXXXXXXXXXXXXMRALGVAVDGGKDSLSMCAHVAGEKVKSPGTLVVSTYAPCPDITVKI 847
A+ + VD +S A G +++ +V + PC
Sbjct: 777 RTEINHIMAKVRRFCAV-LEVDFHFNS----AERNGNLLRA---IVATANTPCVVPYRST 828
Query: 848 EPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLK 907
+P ++ S ++H + + L GS + Q G + K+L L +
Sbjct: 829 KPYFQKVGSTILHLTLLNQNF-LSGSIFCKITGQ-GSDHIIDPAPEAVKNLLMFMLSLKE 886
Query: 908 EKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGIVLEVSKN 967
E ++SGHD+S+GG I TV EM I GL + P + F+E G +EV
Sbjct: 887 ENLVLSGHDVSDGGLIVTVCEMMIAS--GLGATFLIPEFEDPADFCFSETPGFAIEVDAA 944
Query: 968 DLPYVLSEYNNNGVGAQHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFRMWEETSYRLE 1027
++ +L+ ++ + + IG T G D ++ N ++ T + + W S +
Sbjct: 945 NVADILTRAHDQNIWCRPIG-TVVAGSD--FIVFQNDQELMRTSVPKLRHHWSLFSRNIG 1001
Query: 1028 CLQANTDCVLQEWKVLEKRKGA-TYNVTFDPTAA-VIKTKSIKVAVLREEGINGDREMIA 1085
L N E +++E G +T DP + K V VL G ++A
Sbjct: 1002 LLYRNEG----EEELMEDSYGNYELRLTVDPYCIRSLPLKRSNVLVLLLPGCGSPDALLA 1057
Query: 1086 SLMLANFDVFDVTMSDLQNKKITLDAFQGV------VFPGGFSYADTLGSAKGWAAGILF 1139
+L + F + SD + A+ V V G S+ D+ ++
Sbjct: 1058 ALTNSGFLPEVLVASDNKYHSNAFPAYPAVDDFRIGVILYGSSHIDSDVGDSAVKQWLVA 1117
Query: 1140 SESLSSQFAHFKDRKDTFSLGVCN-GCQLMAMLGWVDPDSNSKGSNKAQIFLDHNSSERF 1198
+ + RK +FSL + C+++ + D ++ N+A FL N S R+
Sbjct: 1118 NRHVYKNLRQMLSRKTSFSLAIGQLACRILLATKAIGFDPST---NQAP-FLLPNVSRRY 1173
Query: 1199 ECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLYKNGQVAVQY 1258
E RW KI E+ + R + G V+ W F+ + S L VA +
Sbjct: 1174 ESRWLNFKIPEDTKA--LALRDLRGCVIPCWTQGTHLGFSHHNKSFFGNLVNKQLVAAYF 1231
Query: 1259 VDDD--GKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCPAPCPTVTNP 1316
+ P YP+NP S AG+ S DGRH+A++ P WQ
Sbjct: 1232 HNQQVHSGPATKYPLNPTESEHPYAGICSEDGRHLALLFDPCLAYHAWQ----WQHTKGS 1287
Query: 1317 SVRNSQASPWLRLFQNAYSW 1336
+ SPW +F Y W
Sbjct: 1288 NGLEIAVSPWKLMFYRLYQW 1307
Score = 45.6 bits (103), Expect = 0.009
Identities = 25/57 (43%), Positives = 35/57 (61%), Gaps = 3/57 (5%)
Query: 676 RVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALSYYDLVGSAT 732
+VLR V SK Y+ + +DRC G VAQQ VGP PL+D ++ + ++LV S T
Sbjct: 604 QVLRHPTVGSKAYIVHHMDRCGNGRVAQQPGVGPFDLPLSDYSV---TIHNLVESMT 657
>UniRef50_Q7UMS8 Cluster: Phosphoribosylformylglycinamidine synthase
I; n=2; Planctomycetaceae|Rep:
Phosphoribosylformylglycinamidine synthase I -
Rhodopirellula baltica
Length = 292
Score = 105 bits (252), Expect = 8e-21
Identities = 83/282 (29%), Positives = 121/282 (42%), Gaps = 25/282 (8%)
Query: 1068 KVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTL 1127
+V VLR G N D E + LA V + L +Q + PGGFSY D +
Sbjct: 21 RVLVLRAPGTNCDVETAHAFELAGAVAERVHVGRLMENAALASRYQILCLPGGFSYGDDI 80
Query: 1128 GSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPD---------- 1177
A G L HF D D LG+CNG Q++ LG +
Sbjct: 81 --AAGRILATRMRRHLGDLMHHFVDSGDNLVLGICNGMQVLMRLGVLTSGVGQLQTAGGP 138
Query: 1178 SNSKGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRF 1237
+ S + L N+ RFE RW + + + V+ R + L + AH EG+F
Sbjct: 139 AESADDSVPPATLTWNNHGRFEDRWVNLAV---DKTPCVFLRDIEQMYLPM--AHAEGKF 193
Query: 1238 TVADGSLLDKLYKNGQVAVQYVDDDGK---PTEVYPMNPNGSPDGLAGVRSRDGRHIAMM 1294
D +L++L G++A++Y + G+ T +P+NPNG +AGV GR +M
Sbjct: 194 IARDAEVLEELRSAGRLALRYCEPSGEIQSETLPFPINPNGGDANVAGVCDASGRVFGLM 253
Query: 1295 PHPERCVLRWQCPAPCPTVTNPSVRNSQASPWLRLFQNAYSW 1336
PHPER + Q P P + L++F+NA W
Sbjct: 254 PHPERHIDATQHPFWTRRKEQP-----EHGEGLQMFRNAVEW 290
>UniRef50_O29008 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=1; Archaeoglobus fulgidus|Rep:
Phosphoribosylformylglycinamidine synthase 1 -
Archaeoglobus fulgidus
Length = 271
Score = 105 bits (251), Expect = 1e-20
Identities = 80/256 (31%), Positives = 124/256 (48%), Gaps = 27/256 (10%)
Query: 1065 KSIKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDA------FQGVVFP 1118
+ IKVAVLR EG N + E + + + V + + I + +Q +VFP
Sbjct: 4 EEIKVAVLRMEGTNCEDETVKAFRSLGVEAEAVHIKQFYSDMIRFEEQRSVFDYQCLVFP 63
Query: 1119 GGFSYADTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFS-----LGVCNGCQLMAMLGW 1173
GGFS D + AG +FS + S KD ++ LG+CNG Q++ LG
Sbjct: 64 GGFSAGDYI------RAGAIFSARVKSVLR--KDIEEFIKMGYPILGICNGFQVLVELGA 115
Query: 1174 VDP-DSNSKGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAH 1232
+ D + + K ++ L N S RFECR + +K E+++ ++ + + V+ VAH
Sbjct: 116 LPGFDEDKPLAEKPEMALAMNDSSRFECRPTLLK---KESEKCIFVKNLKKDVVMFPVAH 172
Query: 1233 GEGRFTVADGS---LLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGR 1289
EG+ G L++L N Q+ +YVD+ G YP NPNGS +AG+ +
Sbjct: 173 AEGKVVFPSGKEDEYLERLTSNDQIVFRYVDEKGDYAG-YPWNPNGSFYNIAGICNATHT 231
Query: 1290 HIAMMPHPERCVLRWQ 1305
+MPHPER +Q
Sbjct: 232 VFGLMPHPERAFFGYQ 247
>UniRef50_Q6MIZ1 Cluster: Phosphoribosylformylglycinamidine synthase
I; n=1; Bdellovibrio bacteriovorus|Rep:
Phosphoribosylformylglycinamidine synthase I -
Bdellovibrio bacteriovorus
Length = 239
Score = 104 bits (249), Expect = 2e-20
Identities = 73/233 (31%), Positives = 109/233 (46%), Gaps = 23/233 (9%)
Query: 1075 EGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWA 1134
+GIN + E ++ LA + V ++DL L+ +Q +V PGGFS+ D LGS G
Sbjct: 4 DGINCENETARAVSLAGGEADKVHVNDLLANPGRLNEYQALVIPGGFSFGDHLGS--GQV 61
Query: 1135 AGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQIFLDHNS 1194
+ +L ++ F + LG+CNG Q + LG + PD++ + S L N
Sbjct: 62 LALKLEMNLKNELKQFVKTRPV--LGICNGFQTLIKLGLL-PDADFQRS----CALVKNE 114
Query: 1195 SERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLYKNGQV 1254
F RW +++ NE +W R + + + HGEGRF D SLL +L Q
Sbjct: 115 QGHFIDRW--IEVERNEKSPCIWTRDLPAR-FALPIRHGEGRFVCRDESLLQRLLTQNQA 171
Query: 1255 AVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCP 1307
++Y +D NG+ +AGV G A+MPHPE V W P
Sbjct: 172 VLRYTED-----------VNGAQAQIAGVCDPSGLVFALMPHPEAAVHDWHLP 213
>UniRef50_Q66675 Cluster: Tegument protein; n=1; Equid herpesvirus
2|Rep: Tegument protein - Equid herpesvirus 2 (Equine
herpesvirus 2)
Length = 1345
Score = 103 bits (247), Expect = 3e-20
Identities = 147/640 (22%), Positives = 241/640 (37%), Gaps = 53/640 (8%)
Query: 729 GSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMW-AGKTGVEX 787
G + G Q K + G + + E +TN++ EL ++ + W G
Sbjct: 717 GHVLACGEQGYKMINSGVLGGQYGITEVVTNIMLGPAFELAQLQITAAVHWNEGPDYRAQ 776
Query: 788 XXXXXXXXXXXXXMRALGVAVDGGKDSLSMCAHVAGEKVKSPG--TLVVSTYAPCPDITV 845
+G+A G S A G PG +L + ++A +
Sbjct: 777 LERAVMACREFCAELGVGLAFSSGCSS----AKYGGPSHSPPGPDSLNLISFAGKARVDT 832
Query: 846 ---KIEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLG-DNXXXXXXXXXXKSLFKI 901
++ P L L+H V+ + + GS +K G + +++F+
Sbjct: 833 SAPRLTPELHGPGHVLIHLSVNR-EVLVAGSVFE--HKMTGLRHPLPPVEAHRVRNMFQC 889
Query: 902 TQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGIV 961
Q L+ + +GHD+S+GG I EM + G G+ L ++ + P+ LF+E G V
Sbjct: 890 VQALVARGLVTAGHDVSDGGLIACCAEMALAGQCGVTL--DIQRGIHPLLVLFSETPGAV 947
Query: 962 LEVSKNDLPYVLSEYNNNGVGAQHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFRMW-- 1019
LEV +L VL G IG + VV+ G V L +V W
Sbjct: 948 LEVPLGNLAGVLEACEPFGCFVNQIGTVEPRTGEGHVVVTQGGSVVFRDSLANVMNSWTS 1007
Query: 1020 --EETSYRLECLQANTDCVLQEWKVLEKRKGATYNVTFDPTAAVIKT--KSIKVAVLREE 1075
+E R + +++ E G+ + + ++ + + AVL
Sbjct: 1008 FADEQFSRFGACLKEAEMYRKDYGDNELDAGSLEDACAGGELTLYRSPGRRVGAAVLCLP 1067
Query: 1076 GINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAA 1135
G + +L+ + F+V V DL + + L AF G+V G +++G
Sbjct: 1068 GCTEPLAALHALVNSGFEVSVVGPEDLASSRDGLGAFAGLVVSGVTGARANYAASRGLVQ 1127
Query: 1136 GILFSESLSSQFAHFKDRKDTFSLGVCN-GCQLMAMLGWVDPDSNSKGS----------- 1183
G++ + F +R TFSLG+ G + + G D + G
Sbjct: 1128 GLVAERAARETVLVFLNRTGTFSLGLGELGMEFLCAFGVFDGAAAGGGGEGGGEVGRGLT 1187
Query: 1184 ----NKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGE--GRF 1237
I L+ N+SE E W ++ N V R + G++L W A+G G
Sbjct: 1188 DQSFGNRLIELEANASELPESLWLNFRV--PWNTRSVALRHLAGNILPCW-AYGTHLGVR 1244
Query: 1238 TVADGSLLDKLYKNGQVAVQYVD---DDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMM 1294
ADG L L G +A+ Y D YP NP + +AG+ SRDGRH+ ++
Sbjct: 1245 YRADG-LEYSLDALGMIALHYHGRRAQDWNFARNYPRNPT-AVSTVAGLCSRDGRHLGLL 1302
Query: 1295 PHPERCVLRWQCPAPCPTVTNPSVRNSQASPWLRLFQNAY 1334
P WQ V + SPW LF +
Sbjct: 1303 CDPSAAYHPWQWQH-----VPRRVAGLRTSPWAVLFHTLF 1337
Score = 45.2 bits (102), Expect = 0.012
Identities = 27/66 (40%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
Query: 669 TVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLAD-CAIIALSYYDL 727
T + + VL VASK Y +VDR GLV QQQ VG L PLAD C ++ +
Sbjct: 609 TPYATVHAVLSHPTVASKEYFVRRVDRFSNGLVRQQQGVGALDLPLADYCLVVDPAVETF 668
Query: 728 VGSATS 733
G++ S
Sbjct: 669 TGTSFS 674
>UniRef50_Q2Q0E5 Cluster: Phosphoribosylformylglycinamidine synthase
I; n=1; uncultured organism HF10_3D09|Rep:
Phosphoribosylformylglycinamidine synthase I - uncultured
organism HF10_3D09
Length = 277
Score = 102 bits (245), Expect = 6e-20
Identities = 85/283 (30%), Positives = 131/283 (46%), Gaps = 22/283 (7%)
Query: 1064 TKSIKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSY 1123
++ +KV VL GIN DRE A + + ++ L + L F + PGGFS+
Sbjct: 2 SQDVKVCVLFGFGINCDRETAAVFEMVGGSPERLHVNRLVQGERELSEFDILAVPGGFSF 61
Query: 1124 ADTLGSAKGWAAGILFSESLSSQFAHF-KDRKDTFSLGVCNGCQLMAMLGWVD-PDSNSK 1181
D LGS + + F+ L Q F D K +G+CNG Q + G + P S +
Sbjct: 62 GDHLGSGRLLGNRLRFA--LREQLQRFVTDGKPI--IGICNGFQALVKTGLLPGPQSATI 117
Query: 1182 GSNKAQ-IFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVA 1240
+ Q L N++ R+E RW V + + +W +GM + V HGEGRF
Sbjct: 118 EPDLVQRASLTLNNTGRYEDRW--VTLEFDPQSPCIWTKGM--QRIECPVRHGEGRFVTP 173
Query: 1241 DGSLLDKLYKNGQVAVQYVDD-----DGKPTEV--YPMNPNGSPDGLAGVRSRDGRHIAM 1293
LD+L ++ Q+ V+YVD +G E+ +P++PNGS +AG+ G +
Sbjct: 174 TSKDLDELQESHQLTVRYVDPITLAGEGIQDELLPFPLSPNGSMRNIAGICDATGLVFGL 233
Query: 1294 MPHPERCVLRWQCPAPCPTVTNPSVRNSQASPWLRLFQNAYSW 1336
MPHPE W P T+ + L++F+NA +
Sbjct: 234 MPHPEAFYSMWLHPEH----TSMDIGEDWEGEGLQIFRNAVEY 272
>UniRef50_Q74CN8 Cluster: Phosphoribosylformylglycinamidine synthase
I, putative; n=18; cellular organisms|Rep:
Phosphoribosylformylglycinamidine synthase I, putative -
Geobacter sulfurreducens
Length = 275
Score = 101 bits (243), Expect = 1e-19
Identities = 77/248 (31%), Positives = 115/248 (46%), Gaps = 14/248 (5%)
Query: 1068 KVAVLREEGINGDREMIASLMLANFDVFDVT-MSDLQNKKITLDAFQGVVFPGGFSYADT 1126
+ V+ G N + E + L FD + +SD+ +I LD F + GGF D
Sbjct: 5 RAIVITGNGTNCEMEAAHACRLGGFDETVIAHISDILTGEIRLDDFHFLNLTGGFLDGDD 64
Query: 1127 LGSAKGWAAGILFS------ESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNS 1180
LGSAK A ++ E L Q F D LGVCNG QLM +G + +
Sbjct: 65 LGSAKAQANRFRYARVDDLEEHLIDQIIRFIDAGKLI-LGVCNGFQLMTKMGLLPAVDGA 123
Query: 1181 KGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVA 1240
+ A L N+ RF+ RW +K+ ++ ++ +G+ L + + HGEG+F V
Sbjct: 124 YLAQTAT--LTFNACGRFQDRWVYLKV--DQASPSIYTKGVETG-LYLPIRHGEGKFVVD 178
Query: 1241 DGSLLDKLYKNGQVAVQYVDDD-GKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPER 1299
+ L + Y D+ PT +P+NPNGS + +A V + GR + MMPHPE
Sbjct: 179 SPATLAAIEAKHLAVFTYSDETYSAPTMEFPLNPNGSVNAIAAVCNESGRLMGMMPHPEA 238
Query: 1300 CVLRWQCP 1307
+ R P
Sbjct: 239 FLHRTNHP 246
>UniRef50_A0B5C6 Cluster: Phosphoribosylformylglycinamidine synthase
I; n=1; Methanosaeta thermophila PT|Rep:
Phosphoribosylformylglycinamidine synthase I -
Methanosaeta thermophila (strain DSM 6194 / PT)
(Methanothrixthermophila (strain DSM 6194 / PT))
Length = 262
Score = 101 bits (242), Expect = 1e-19
Identities = 60/249 (24%), Positives = 114/249 (45%), Gaps = 11/249 (4%)
Query: 1067 IKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADT 1126
+++AV++ G N + E + ++ D + + + L F G V PGGFSY D
Sbjct: 1 MRIAVIQFPGTNCEHETLVAVRECGMDGEIFRWNRPEQE---LCEFDGYVIPGGFSYQDR 57
Query: 1127 LGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKA 1186
+ AG++ S+ + +G+CNG Q++ G + + +
Sbjct: 58 V------RAGVIASKEPVMATLREEAANGKPIIGICNGFQILVESGILPFGDGVRLALAQ 111
Query: 1187 QIFLDHNSSER--FECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSL 1244
+ + R + C W+ ++ E + + G +L + +AH EG +D +
Sbjct: 112 NVMIRGGEIVRRGYYCAWTMLRHDAEEKRCSGSYILRRGEILSIPIAHAEGNLVASDRKV 171
Query: 1245 LDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRW 1304
+++L ++ Q+ +Y G+ +P+N NGS + +AG+ + +G + MMPHPER W
Sbjct: 172 IERLIEDDQIVFRYCSPQGEIINEFPVNVNGSTENIAGISNPEGNVLGMMPHPERAFFAW 231
Query: 1305 QCPAPCPTV 1313
Q P P +
Sbjct: 232 QLPRKHPRI 240
>UniRef50_Q74CN9 Cluster: Phosphoribosylformylglycinamidine synthase
II, putative; n=19; cellular organisms|Rep:
Phosphoribosylformylglycinamidine synthase II, putative -
Geobacter sulfurreducens
Length = 996
Score = 99.1 bits (236), Expect = 7e-19
Identities = 185/820 (22%), Positives = 296/820 (36%), Gaps = 73/820 (8%)
Query: 217 LKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLIDMVASTQKTSNNNNVIK- 275
L PT EL +AQ+ SEH +H F G + + N I + T V +
Sbjct: 228 LAAKPTDAELEAIAQTWSEHCKHKIFSGTIEYIDENGNREEIRSLFKTFIQGTTKTVREQ 287
Query: 276 FGDNSSAIKGFQHTILRPTNVRGPSQVIQKKTESDIIFTAETHNMPTAVAPFSGATTGTG 335
G+ + F+ + VI+ + ++F ETHN P+A+ P+ GA TG
Sbjct: 288 LGERDFCLSVFKDN----------AGVIRWNDDWSLVFKVETHNSPSALDPYGGALTGIV 337
Query: 336 GRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNG 395
G RD G G+G + T + + P YD P PS P +I G
Sbjct: 338 GVNRDPFGTGKGSKLIFNTDVFCFAS---PFYDKP-------LPSRLLHPRRIYEGVVEG 387
Query: 396 ASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKNKPDKGML 455
GNK G P ++G + + + A KP++F G G MP ++ P
Sbjct: 388 VEHGGNKSGIPTVNGSI-VFDDRFAG-------KPLVFCGTAGLMPATI--NGAPAHEKF 437
Query: 456 LVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLESD 515
+ + AVQ GD R+ + D
Sbjct: 438 IRPGDLIVMTGGRIGKDGIHGATFSSEELHEGSPVTAVQIGDPITQKRMTDFL--IRARD 495
Query: 516 VNPVESIHDQGAGGNGNVLKELV-EPEGAVVFTKEFQLGDPTITTLELWGAEYQENDALL 574
I D GAGG + + E+ E G + + L P + E+ +E QE +L
Sbjct: 496 KGLYNFITDNGAGGLSSSIGEMSGECGGCRMDLSKAPLKYPGLDPWEILISEAQERMSLA 555
Query: 575 CSKANRHILEEICRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPY 634
+ + RR + +GE T GY ++ Y ++ + + LP
Sbjct: 556 VPPEHIDEFIAMARRFGVEATILGEFTDSGYFHIM---YGDRTI-----------AYLPM 601
Query: 635 D-LHLEAVLGNMPRKTFDLQTEKRTKLP-LSFPKDITVKSALDRVLRLVNVASKRYLTNK 692
D LH G P + + KR + P L +D + L ++L +N+ SK + +
Sbjct: 602 DFLH----GGLPPMQMRGVWEVKRHEEPALEVKQDYA--ADLKQLLGSLNICSKESVVRR 655
Query: 693 VDRCVTGLVAQQQCVGPLHTPLADCAIIALSYYDLVGSATSIGTQNIKGLLDPAAGARLS 752
D V G + G + +D A+I G S G +D +
Sbjct: 656 YDHEVQGGSVVKPFTGVANDGPSDAAVIRPVLDSFEGVVVSHGICPRYSDIDAYHMTANA 715
Query: 753 LGEALTNLVFAGISELEDVKCSGNWMW-----AGKT---GVEXXXXXXXXXXXXXXMRAL 804
+ EAL N V G L+ V N+ W + KT + A
Sbjct: 716 IDEALRNYVAVG-GSLDLVAGLDNFCWCDPVQSDKTPDGEYKMAQLVRSNKALYDYCVAF 774
Query: 805 GVAVDGGKDSLSMCAHVAGEKVKSPGTLVVSTYAPCPDITVKIEPALKEENSALVHAPVS 864
G+ + GKDS+ K+ P TL+ S DI + K +V+
Sbjct: 775 GIPLISGKDSMKNDFWDGNVKISIPPTLLFSVIGKIDDIRTAVTMDAKRPGD-IVYLLGK 833
Query: 865 PGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFIT 924
G Y LGGS K L N ++ + + + + S HD+S+GG
Sbjct: 834 TG-YELGGSEY-MALKGLVGNSVPQVNTAKALPRYRALHRAISQGLVASCHDLSDGGLAV 891
Query: 925 TVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGIVLEVSKNDLPYVLSEYN---NNGV 981
+ E G G+ ++ S EAL + + E + L V E + +
Sbjct: 892 ALAETAFAGGFGIVAELS-RVLWSGDEALKGDAALLFSESASRHLVTVRPENREAFESVM 950
Query: 982 GAQHIGYTGKYGMDSQV-VINLNGVNVLDTVLIDVFRMWE 1020
A G + +V V L+G V+D + ++ + W+
Sbjct: 951 AANCFSSIGVVTEEGRVTVTGLSGTRVIDAGIDELKQAWQ 990
>UniRef50_Q6MIZ0 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=1; Bdellovibrio bacteriovorus|Rep:
Phosphoribosylformylglycinamidine synthase II -
Bdellovibrio bacteriovorus
Length = 1009
Score = 97.5 bits (232), Expect = 2e-18
Identities = 177/749 (23%), Positives = 282/749 (37%), Gaps = 81/749 (10%)
Query: 222 TSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLIDMVASTQK--TSNNNNVIKFGDN 279
T VEL LAQ+ SEH +H F ++ + E+ D A K TS + I+
Sbjct: 235 TEVELECLAQTWSEHCKHKIFAAEV-----DYTEACGDFPALGDKKITSLYKSYIQKATK 289
Query: 280 SSAIKGFQHTILRPTNVRGPSQVIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIR 339
G+ ++ + + ++ ++ ++ ETHN P+A+ PF GA TG G R
Sbjct: 290 DLDDCGYLVSVFKDN-----AGIVDFDSKLNVCVKVETHNSPSALDPFGGALTGILGVNR 344
Query: 340 DVQGVGRGGHTVAGTAGYSVGNLHI-PGYDLPWEEKGWEYPSNFATPLQIIIEASNGASD 398
D+ G G G VA T + + ++ P D P + P P I G +
Sbjct: 345 DILGCGLGAKPVANTDVFCLSTPNLFPASDSP------QRPELLKDPGVIFRGVHQGVEE 398
Query: 399 YGNKFGEPVISGFVQSYGLKNADNTREEF-VKPIMFSGGIGYMP---HSMIKKNKPDK-G 453
GN+ G P I+G A EF KP++F G +G MP H ++K + G
Sbjct: 399 GGNQSGIPTING---------AFCFASEFAAKPLIFVGSVGVMPKTVHGRASESKEIRPG 449
Query: 454 MLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLE 513
L+V A + VQ GD+ RL
Sbjct: 450 DLIVVAGGRLGKDGVHGATFSSLALHDNVASN------VVQIGDSITQKRLLDFT--LKA 501
Query: 514 SDVNPVESIHDQGAGGNGNVLKELVEPEGAVVFTKEFQLGDPTITTLELWGAEYQEN-DA 572
D +++I D GAGG + + E+ + G + L + LE W E+ +
Sbjct: 502 RDNGWIQAITDNGAGGVSSSIGEMAQYSGGA--RMDLGLHPVKYSGLEYWEMLVSESQER 559
Query: 573 LLCSKANRHILE--EICRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKS 630
+ + + H+++ + R +GE T G + E E S
Sbjct: 560 MSYAVSPNHLMDFMNLARHMGVEAFVLGEFTDSGSFDIFHGK--EPLAKLKLEFLHEGLS 617
Query: 631 KLPYDLHLEAVLGNMPRKTFDLQTEKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLT 690
++ H + K + K PL+ D+ +AL +VL NVAS+ L
Sbjct: 618 RMKLKAHFDG------PKQYQEYFRAEGKAPLT-GNDLA--AALKKVLANPNVASREPLV 668
Query: 691 NKVDRCVTGLVAQQQCVGPLHTPLADCAIIALSYY---DLVGSATSIGTQNIKGLLDPAA 747
D V G + G + D ++ LS + D A S G D
Sbjct: 669 RYYDHEVQGATRVKPYGGKTQSGANDAGVLDLSVHGGDDNNAVAVSNGLCPQFSWYDTYL 728
Query: 748 GARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEXXXXXXXXXXXXXXMRALGVA 807
A+ ++ E++ NLV G ++ + N+ W T +RA
Sbjct: 729 MAQKAVDESVRNLVATG-ADPAKMALVDNFCWPDPT--PKASNPDAAHKMAQLVRACAGL 785
Query: 808 VD----------GGKDSL--SMCAHVAG---EKVKSPGTLVVSTYAPCPDITVKIEPALK 852
D GKDS+ G K+ P TL+V+ A PD T K P
Sbjct: 786 YDAALAYRAPFVSGKDSMKNDFIGKTKGGDTVKISVPPTLLVTAMAQVPDAT-KTAPGFF 844
Query: 853 EENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLKEKKLI 912
+ L++ +P + L S L+Q + + ++ K L+ ++ L
Sbjct: 845 QNAGDLIYLLGTPTQ-SLYASVLSQEF-TVPESAPEYPNLARNKDLYFRIFTAHQKTLLQ 902
Query: 913 SGHDISEGGFITTVLEMGIGGVRGLNLHV 941
S HDISEGG +T + E G G G+ L++
Sbjct: 903 SCHDISEGGLMTALAESGFGNNLGMKLNL 931
>UniRef50_A6C4F9 Cluster: Phosphoribosylformylglycinamidine synthase
I; n=1; Planctomyces maris DSM 8797|Rep:
Phosphoribosylformylglycinamidine synthase I -
Planctomyces maris DSM 8797
Length = 271
Score = 95.5 bits (227), Expect = 9e-18
Identities = 73/252 (28%), Positives = 114/252 (45%), Gaps = 23/252 (9%)
Query: 1068 KVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTL 1127
KV VLR G N D E + L + + + L L+ +Q + PGGFSY D +
Sbjct: 6 KVCVLRAPGTNCDIETAHAFDLCGAESTRIHLLKLLKNPSQLNDYQILCLPGGFSYGDDV 65
Query: 1128 GSAKGWAAGILFSESLSSQFAHFKDR---KDTFSLGVCNGCQLMAMLGWVDPDSNS---K 1181
G AG++F+ L Q A D LG+CNG Q++ G + + +
Sbjct: 66 G------AGVIFASHLQGQLADVIGNFLAADKLVLGICNGFQVLLKAGILPGGAAGWPPQ 119
Query: 1182 GSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVAD 1241
L N++ ++ W + + +N V+ +G+ L + AH EGR V D
Sbjct: 120 ADQSRDATLTWNTNGKYTSLWVNLGVVAPQN---VFLKGIDQIELPI--AHAEGRIAVND 174
Query: 1242 GSLLDKLYKNGQVAVQYVDDDGKPTEV------YPMNPNGSPDGLAGVRSRDGRHIAMMP 1295
++++ N Q+A+ Y D T + YP+NPNGS +A + GR + +MP
Sbjct: 175 PAIIEGWKANQQIAMCYRDAGDTETMLQEEILPYPVNPNGSACNIAALSDPAGRVLGLMP 234
Query: 1296 HPERCVLRWQCP 1307
HPER + Q P
Sbjct: 235 HPERFLFATQHP 246
>UniRef50_O67190 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=40; cellular organisms|Rep:
Phosphoribosylformylglycinamidine synthase 1 - Aquifex
aeolicus
Length = 227
Score = 95.5 bits (227), Expect = 9e-18
Identities = 65/208 (31%), Positives = 109/208 (52%), Gaps = 25/208 (12%)
Query: 1093 DVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKD 1152
D+ + + + ++ L + VV PGGFS+ D L G L + + +Q +
Sbjct: 23 DILEKDVEFVYWEEKNLSKYDVVVLPGGFSFGDYL------RPGALAARTPLAQAIYDFA 76
Query: 1153 RKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQIFLDHNSSERFECRWSAVKIHENEN 1212
+K + +G+CNG Q++ LG + P + L N + RF C+W +++ EN
Sbjct: 77 QKGKYVIGICNGFQILTELGLL-PGA-----------LLPNLNMRFVCKWVNLRV---EN 121
Query: 1213 KEDVWFRGMG-GSVLGVWVAHGEGRFTVADGSLLDKLYKNGQVAVQYVDDDGKPTEVYPM 1271
+ + R + G VL + +AH +GR+ V + L K+ +NGQ+ +Y D+ G+ E +
Sbjct: 122 ERSAFTRKLEKGDVLRIPIAHHDGRYYVPEEELR-KMEENGQILFRYCDEQGEVKE--EV 178
Query: 1272 NPNGSPDGLAGVRSRDGRHIAMMPHPER 1299
NPNGS +AGV +++G MMPHPER
Sbjct: 179 NPNGSVSNIAGVMNKEGNVFGMMPHPER 206
>UniRef50_Q8B409 Cluster: Tegument protein/v-FGAM-synthase; n=4;
Suiformes rhadinovirus genogroup 1|Rep: Tegument
protein/v-FGAM-synthase - Porcine lymphotropic
herpesvirus 3
Length = 1378
Score = 95.1 bits (226), Expect = 1e-17
Identities = 137/634 (21%), Positives = 250/634 (39%), Gaps = 55/634 (8%)
Query: 727 LVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVE 786
L G +++G QN+ D G ++ EAL NL + + LE V + + W V+
Sbjct: 731 LWGICSALGEQNVISQFDVKEGIAWAITEALFNLCLSPLEMLEHVIVTMAFGWPLVRNVK 790
Query: 787 XXXXXXXXXXXXXXMRALGVAVDGGKDSLSMCAHV--AGEKVKSPGTLVVSTYAPCPDIT 844
+ LGV+ + + +C + +G+ P + PC +
Sbjct: 791 TEMKEAMLYARNFCEK-LGVSFE-----VDLCKQINNSGDGTAGPRHITACASCPCALPS 844
Query: 845 VKIEPALK-EENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQ 903
KI P L+ + S L+H + G K G + + + + +
Sbjct: 845 YKITPYLRLKRGSQLLHVSLVKSLTSQGSIYTELTGKAFGVSSLNINPQLLRQVILFLIE 904
Query: 904 KLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGIVLE 963
+ KE ++SGHD+S+GG + + EM I + + V IE L ++ G+V++
Sbjct: 905 -IKKEGLIVSGHDVSDGGLFSCIAEMVIAS--ATKAQIIIPPKVETIEFLCSQTPGVVIQ 961
Query: 964 VSKNDLPYVLSEYNNNGVGAQHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFRMWE--- 1020
V + ++S+ V IG G+ + I + + L + WE
Sbjct: 962 VFSEHVRSIISKAKRMRVSCTVIGNVHD-GLPPGLEIVQGSATLANFSLKQLRANWELYA 1020
Query: 1021 ---ETSYRLECLQANTDCVLQEWKVLEKRKGATYNVTFDPTAAVIKTKSIKVAVLREEGI 1077
+ +R E ++ D V +++V+ ++ NV D + KV V G
Sbjct: 1021 SKQDLLWRNEGEESLDDSVYGDYEVVLPKECFYINVLPD--------ERHKVTVYLLPGC 1072
Query: 1078 NGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQ-----GVVFPGGFSYADTLGSAKG 1132
N ++A+L + + ++ S D GV+ G + DT
Sbjct: 1073 NRPDALLAALTGSGCNPRVISTSGQTTLGTVHDRLSDGTTVGVIIYGTPNITDTESGMNA 1132
Query: 1133 WAAGILFSESLSSQFAHFKDRKDTFSLGV-CNGCQLMAMLGWVDPDSNSKGSNKAQIFLD 1191
+ +L ++ + + + FS+ + CQL+ + ++ +GS +
Sbjct: 1133 MSQYVLRNKHIIRDIQNVLKMRGRFSVAIGPMACQLLFESKMIS-YTHLEGSVPTVV--- 1188
Query: 1192 HNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLYKN 1251
N S R+E RW + H +N + + F+ + G +L W F + + ++ +
Sbjct: 1189 KNVSGRYESRW--LNFHIPQNTKAIAFQDLKGCILPCWAQGTHLGFGHKNPEVFAQMEER 1246
Query: 1252 GQVAVQYVD---DDGKPTEVYPMNPN-GSPDGLAGVRSRDGRHIAMMPHPERC--VLRWQ 1305
GQVA + DG P YP+NP+ G P AG+ S DGRH+A++ P +WQ
Sbjct: 1247 GQVASMFYGQRASDG-PASKYPLNPSEGYP--YAGLCSEDGRHLALLYDPCLAFHTSQWQ 1303
Query: 1306 CPAPCPTVTNPSVRNSQASPWLRLFQNAYSWAIN 1339
N + SPW +F W+I+
Sbjct: 1304 -------HVNKVDADRLVSPWKMMFYRLQLWSIS 1330
Score = 51.2 bits (117), Expect = 2e-04
Identities = 39/147 (26%), Positives = 67/147 (45%), Gaps = 10/147 (6%)
Query: 577 KANRHILEEICRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDL 636
K L+ +CR CPV ++GE+T ++ + T +F E L + ++
Sbjct: 533 KVTSRRLKMMCRAFGCPVLYLGEITD----TITDIVVTGEFHGSPENLTFKKT-----NV 583
Query: 637 HLEAVLGNMPRKTFDLQTEKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRC 696
+ +P + ++ T +S KS L +L+ V SK+Y+ DRC
Sbjct: 584 KTSSPENPIPVR-WEAPAFTGTSPSMSISSQDDAKSLLLSILQHPTVGSKKYIVYHTDRC 642
Query: 697 VTGLVAQQQCVGPLHTPLADCAIIALS 723
G +AQQQ VGP P++D ++ L+
Sbjct: 643 GNGHIAQQQGVGPFDCPVSDYSVQILN 669
>UniRef50_Q3DJT6 Cluster: Phosphoribosylformylglycinamidine synthase;
n=47; Streptococcus|Rep:
Phosphoribosylformylglycinamidine synthase -
Streptococcus agalactiae 515
Length = 1266
Score = 94.3 bits (224), Expect = 2e-17
Identities = 59/186 (31%), Positives = 94/186 (50%), Gaps = 7/186 (3%)
Query: 1115 VVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWV 1174
+ F GGFS AD + + IL +E + + F + K +G+CNG Q + G +
Sbjct: 1059 IFFAGGFSAADEPDGSAKFIVNILLNEKVRAAIDSFIE-KGGLIIGICNGFQALVKSGLL 1117
Query: 1175 DPDSNSKGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMG-GSVLGVWVAHG 1233
P N + + + L +N + + + +I N W G+ G + + V+HG
Sbjct: 1118 -PYGNFEEAGETSPTLFYNDANQHVAKMVETRI---ANTNSPWLAGVEVGDIHAIPVSHG 1173
Query: 1234 EGRFTVADGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAM 1293
EG+F V+ S +L NGQ+ QYVD DG+P+ NPNGS + + G+ S++G+ I
Sbjct: 1174 EGKFVVS-ASEFAELRDNGQIWSQYVDFDGQPSMDSKYNPNGSVNAIEGITSKNGQIIGK 1232
Query: 1294 MPHPER 1299
M H ER
Sbjct: 1233 MGHSER 1238
Score = 51.2 bits (117), Expect = 2e-04
Identities = 93/424 (21%), Positives = 163/424 (38%), Gaps = 49/424 (11%)
Query: 198 GLAFDTWDMEFYMDLFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLV-LD------G 250
GLA + D+ F D F + R PT EL L S+H RH F+ +L +D
Sbjct: 213 GLAMEVDDLLFIQDYF-KSIGRVPTETELKVLDTYWSDHCRHTTFETELKNIDFSASKFQ 271
Query: 251 KEINESLIDMVASTQKTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRGPSQV----IQKK 306
K++ + +A + + D ++ ++ R ++ ++ ++ +
Sbjct: 272 KQLQATYDKYIAMRDELGRSEKPQTLMDMATIFGRYERANGRLDDMEVSDEINACSVEIE 331
Query: 307 TESD-------IIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSV 359
+ D ++F ETHN PT + PF GA T GG IRD GR +
Sbjct: 332 VDVDGVKEPWLLMFKNETHNHPTEIEPFGGAATCIGGAIRDPLS-GR-SYVYQAMRISGA 389
Query: 360 GNLHIPGYDLPWEEKGWEYPSNFATPLQIIIE-ASNGASDYGNKFGEPVISGFVQSYGLK 418
G++ P + G P Q+I + A++G S YGN+ G + + +V+ Y
Sbjct: 390 GDITTP---IAETRAG-------KLPQQVISKTAAHGYSSYGNQIG--LATTYVREY--- 434
Query: 419 NADNTREEFVKPIMFSGG-IGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXX 477
FV M G +G P + + KP+ G ++V
Sbjct: 435 ----FHPGFVAKRMELGAVVGAAPKENVVREKPEAGDVVVLLGGKTGRDGVGGATGSSKV 490
Query: 478 XXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLESDVNPVESIHDQGAGGNGNVLKEL 537
+ VQ+G+A ++ R+ R + ++ +D GAGG + EL
Sbjct: 491 QTVESVETAGAE---VQKGNAIEERKIQRLFRD--GNVTRLIKKSNDFGAGGVCVAIGEL 545
Query: 538 VEPEGAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFV 597
+G + + L + E+ +E QE +++ ++ C +E V
Sbjct: 546 A--DGLEIDLDKVPLKYQGLNGTEIAISESQERMSVVVGPSDVDAFIAACNKENIDAVVV 603
Query: 598 GEVT 601
VT
Sbjct: 604 ATVT 607
>UniRef50_A1IAB2 Cluster: Phosphoribosylformylglycinamidine synthase
I; n=2; Deltaproteobacteria|Rep:
Phosphoribosylformylglycinamidine synthase I - Candidatus
Desulfococcus oleovorans Hxd3
Length = 276
Score = 94.3 bits (224), Expect = 2e-17
Identities = 69/234 (29%), Positives = 109/234 (46%), Gaps = 11/234 (4%)
Query: 1066 SIKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYAD 1125
S+ +L G+N D E + A V ++ L + + TL+ F + F GGFS+ D
Sbjct: 4 SVNALILSGYGLNCDNETAFAFEQAGARAERVHINALISGQKTLEDFHILAFVGGFSWGD 63
Query: 1126 TLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNK 1185
G+ G L F +R +G+CNG Q + LG + P + + +
Sbjct: 64 DHGA--GVIQAHRMKTRLGKDMVAFVERGGLV-IGICNGFQTLVNLGLL-PGIDGDYATR 119
Query: 1186 AQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLL 1245
+ + L N F W + + N V+ +G+ L + + HGEG+F + +L
Sbjct: 120 S-VALIANDCGNFRDDWVTLAV--NTASPCVFTKGIAS--LDLPIRHGEGKF-FCEPDIL 173
Query: 1246 DKLYKNGQVAVQYVDDDGKPTEV-YPMNPNGSPDGLAGVRSRDGRHIAMMPHPE 1298
L N QV ++Y D+ G P + +P NPNGS D +AG+ GR +MPHPE
Sbjct: 174 AALAANSQVVMRYADESGAPAKGRFPQNPNGSVDDIAGICDTTGRVFGLMPHPE 227
>UniRef50_A7PSW6 Cluster: Chromosome chr8 scaffold_29, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr8 scaffold_29, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 368
Score = 92.7 bits (220), Expect = 6e-17
Identities = 42/89 (47%), Positives = 58/89 (65%)
Query: 362 LHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNAD 421
L+I G+ PWE+ + YPSN A+ LQI+++AS+GASD NKFGEP+I + G+K
Sbjct: 240 LNIEGFYAPWEDPSFTYPSNLASSLQILVDASSGASDCRNKFGEPLIQSCTGTIGMKLLS 299
Query: 422 NTREEFVKPIMFSGGIGYMPHSMIKKNKP 450
R E++ PIMF+ GIG + H I K P
Sbjct: 300 EERREWLMPIMFNAGIGQIDHIHITKGVP 328
>UniRef50_Q9HNU2 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=4; Halobacteriaceae|Rep:
Phosphoribosylformylglycinamidine synthase 1 -
Halobacterium salinarium (Halobacterium halobium)
Length = 224
Score = 89.0 bits (211), Expect = 8e-16
Identities = 81/236 (34%), Positives = 109/236 (46%), Gaps = 32/236 (13%)
Query: 1069 VAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLG 1128
VAV+R G N DR+ + +L D D + D GVV PGGFSY D L
Sbjct: 3 VAVVRFGGSNCDRDAVRALAHLGVDAAVAWHDD----GLPADT-DGVVVPGGFSYGDYL- 56
Query: 1129 SAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQI 1188
AG + ++S LGVCNG Q+ G + P + +
Sbjct: 57 -----RAGAMAAQSPVVAEVRALAADGVPVLGVCNGAQIGCEAG-LAPGAFTT------- 103
Query: 1189 FLDHNSSERFECRWSAVKIHENENKEDVWFRGMG-GSVLGVWVAHGEGRFTVADGSLLDK 1247
N+S RF+C +++ EN W G VL + +AHGEGRF + D + D
Sbjct: 104 ----NASARFQCERVHLRV---ENATTPWTAAYSEGDVLEIPIAHGEGRFEIDDDAYAD- 155
Query: 1248 LYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIA-MMPHPERCVL 1302
L + +V +Y + DG+ TE NPNGS +AGV D H+A MMPHPER L
Sbjct: 156 LVADDRVLFRYCNADGEVTEA--ANPNGSTGAVAGVTG-DRDHVAVMMPHPERATL 208
>UniRef50_Q5GT14 Cluster: Phosphoribosylformylglycinamidine (FGAM)
synthase, synthetase domain; n=16; Rickettsiales|Rep:
Phosphoribosylformylglycinamidine (FGAM) synthase,
synthetase domain - Wolbachia sp. subsp. Brugia malayi
(strain TRS)
Length = 1045
Score = 88.2 bits (209), Expect = 1e-15
Identities = 168/756 (22%), Positives = 284/756 (37%), Gaps = 76/756 (10%)
Query: 194 NDKLGLAFDTWDMEFYMDLFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEI 253
N LGL+ M+ D F NKL R+P +EL LAQ+ SEH +H F + EI
Sbjct: 267 NGTLGLSLTA--MKAIKDYF-NKLGRNPYDIELESLAQTWSEHCKHNIFCSPI----DEI 319
Query: 254 NESLID--MVASTQKTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRGPSQVIQKKTESDI 311
+ L + +T++ ++N + F DN+ I F L I
Sbjct: 320 KDGLYAHYIKRATREINSNICMSVFSDNAGGII-FDDDYL-------------------I 359
Query: 312 IFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPW 371
+ ETHN P+A+ PF GA TG G RD+ G G+G + T + + +
Sbjct: 360 VDKVETHNSPSALDPFGGAMTGVLGVNRDIVGFGKGAEPIMNTYYFCFAKEAKGKF---Y 416
Query: 372 EEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKPI 431
+K E P I+ E +G + GN G P G V DN KP+
Sbjct: 417 RDK--ERTDEILLPKYIMKEVIHGVNVAGNCSGIPTQLGSVY------FDN--RFCGKPL 466
Query: 432 MFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFG 491
+F G +G +P ++ N P +A
Sbjct: 467 VFVGSVGIIPRNI--NNAPSHIKKPQNGDKIVIIGGRVGRDGIHGATFSSEALSGNSPST 524
Query: 492 AVQRGDAEMGNRLNRVVRGCLES-DVNPVESIHDQGAGGNGNVLKELVEPEGAVVFTKEF 550
VQ GD +L+ V +E+ D+ +I D GAGG + + E+ + +G V +
Sbjct: 525 VVQIGDPITQKKLSNAV---IEARDLGLYNAITDNGAGGLSSSIGEMGK-DGFEVDLSKV 580
Query: 551 QLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGEVTGDGYMSLIE 610
L + E+W +E QE L + N + ++I ++ VS +GE G MS +
Sbjct: 581 LLKSDGMAPWEIWISESQERMTLAVPEENLPMFKQIMKKHDVEVSVIGEFNSTG-MSTVR 639
Query: 611 DSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEK-RTKLPLSFPKDIT 669
++ + K +HL+ + F T ++ ++ +++
Sbjct: 640 IHSASPIMNIETEFLHDGNPK----MHLKT------KPWFKETTATLASRAGITLSQEVE 689
Query: 670 VKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALSYYDLVG 729
+K L R N+ SK ++ + D V G + G ++ ++ G
Sbjct: 690 LKEMLSR----PNICSKEFIVVQYDHEVQGSSVLKPLQGKGRV-CSEAVVLRPILSSNKG 744
Query: 730 SATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEXXX 789
S G + G +D A ++ A+ N V AG +E + N+ W E
Sbjct: 745 VVKSQGFGSSYGEIDTYHMAACAIDTAIRNYVAAG-GNIEHLALLDNFCWCDAYNPERLW 803
Query: 790 XXXXXXXXXXXMR-ALGVAVDGGKDSL---SMCAHVAGEKV--KSPGTLVVSTYAPCPDI 843
A GKDS+ G+KV +P +L++S +I
Sbjct: 804 QLKRAAEACYDYAIAFKTPFISGKDSMFNDFKGYDENGKKVIISAPPSLLISAIGIIENI 863
Query: 844 TVKIEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQ 903
+ +K + ++ + LG S Q Y + +N + L+K
Sbjct: 864 ENAVSLDVKMPGDLIYMLGITHDE--LGRSEY-QLYSGIDNNNVPKVDAKNARKLYKCFN 920
Query: 904 KLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNL 939
+ +KE + S ++ GG +++ I G G +
Sbjct: 921 QAIKESIVASAIALNLGGLAIALVKSLIAGDLGAEI 956
>UniRef50_Q6M0T9 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=7; Euryarchaeota|Rep:
Phosphoribosylformylglycinamidine synthase II -
Methanococcus maripaludis
Length = 989
Score = 87.8 bits (208), Expect = 2e-15
Identities = 175/749 (23%), Positives = 282/749 (37%), Gaps = 78/749 (10%)
Query: 213 FVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLIDMVASTQKTSNNNN 272
+ K R+PT +EL LAQ+ SEH +H F ++ +I E + + + N
Sbjct: 227 YYQKEGRNPTDIELEALAQTWSEHCKHTIFASQI----DDIEEGIFKKYI---RNATNEI 279
Query: 273 VIKFGDNSSAIKGFQHTILRPTNVRGPSQVIQKKTESDIIFTAETHNMPTAVAPFSGATT 332
+ G+ I F S I E + AETHN P+A+ PF GA T
Sbjct: 280 REELGEKDFCISVFSDN----------SGGIIFDDEWMVTDKAETHNSPSALDPFGGAIT 329
Query: 333 GTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEA 392
G G RD G G G VA G+ VG D +G + P +I+
Sbjct: 330 GIVGVNRDTVGFGLGALPVANKYGFCVGRPE----DTEIIYRGQNKTNPSLLPRRILDGI 385
Query: 393 SNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKNKPDK 452
+G + GN+ G P +GFV D+T + KP++F G IG +P + +
Sbjct: 386 VHGVNVGGNQSGIPTPNGFVY------FDDTYKG--KPLVFVGTIGLIPRK-LPDGRLSH 436
Query: 453 GMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCL 512
+A D AVQ GD +L+ V
Sbjct: 437 EKAAENGDNIVIIGGRVGKDGIHGATFSSEAMDEGSPAAAVQIGDPITQKKLSDAVIK-E 495
Query: 513 ESDVNPVESIHDQGAGGNGNVLKELVEP-EGAVVFTKEFQLGDPTITTLELWGAEYQEND 571
D SI D GAGG + E+ E G VV +E L P + E+W +E QE
Sbjct: 496 ARDKGLYNSITDNGAGGISCSVAEMAEECGGFVVELEEVPLKYPGLEPWEIWISESQERV 555
Query: 572 ALLCSKANRHILEEICRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSK 631
L LEE + ++ G +E KF + ++R + K
Sbjct: 556 TLSVPDDK---LEEFMD--------LMKIRG------VEAVVIGKF-NNTDRAVVNYNGK 597
Query: 632 LPYDLHLEAVLGNMP-RKTFDLQTEKRTKLPLSFPKDITVKSAL---DRVLRLVNVASKR 687
DL ++ + +P RK RT+ P +ITV++ L +++L N S
Sbjct: 598 TIMDLEMDFLHNGLPKRKLITKPYSYRTEEP-----EITVENQLETFEKILGNHNNCSFE 652
Query: 688 YLTNKVDRCV--TGLVAQQQCVGPLHTPLADCAIIALSYYDLVGSATSIGTQNIKGLLDP 745
Y++ + D V ++ Q G ++ + + S LV S + + + D
Sbjct: 653 YISKQYDHEVQNNSVIKPLQGKGRVNGTASVIRPLLSSQKGLVMSQSLLPRLSEISCYDM 712
Query: 746 AAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEXXXXXXXXXXX-XXXMRAL 804
AA A + A+ N V G + + N+ W E +
Sbjct: 713 AACA---MDTAIRNCVAVG-GNINHIAIMDNFCWCSSDEPERLYQLKDAAKSCYDYAKTY 768
Query: 805 GVAVDGGKDSLSMCAHVAGE-----KVKSPGTLVVSTYAPCPDI--TVKIEPALKEENSA 857
+ GKDS+ E K+ TL++S +I T ++ LK++
Sbjct: 769 LTPLISGKDSMFNDFKGFDENNNPIKISVHPTLMMSALGVIDNIEHTNSMDLKLKDD--- 825
Query: 858 LVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDI 917
L++ + K GGS + ++G + L++ +L ++ S +
Sbjct: 826 LIYV-IGETKDECGGSEFYHAFGEVG-GISPKVDAKSARKLYEKMYELSQKGIFSSCASV 883
Query: 918 SEGGFITTVLEMGIGGVRGLNLHVNVAAN 946
+ GG + T+ +M I G GL ++ A N
Sbjct: 884 AAGGLVITLAKMAISGCLGLEADLSKAPN 912
>UniRef50_Q2GDW3 Cluster: Putative phosphoribosylformylglycinamidine
synthase I; n=1; Neorickettsia sennetsu str.
Miyayama|Rep: Putative phosphoribosylformylglycinamidine
synthase I - Neorickettsia sennetsu (strain Miyayama)
Length = 240
Score = 87.4 bits (207), Expect = 2e-15
Identities = 73/271 (26%), Positives = 124/271 (45%), Gaps = 39/271 (14%)
Query: 1069 VAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLG 1128
V VL G+N + E + + L+ F + + DL NK L Q + PGGFS+AD G
Sbjct: 4 VLVLSGYGLNCEDETLRAFELSGFAGSVLHLDDLLNKPNKLCNHQVLAIPGGFSFADNTG 63
Query: 1129 SAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQI 1188
+ +A + L + +F + KD +G+CNG Q++ L ++
Sbjct: 64 AGNAFACKTI---PLLEEVENFLN-KDKLVIGICNGAQILTRL-----------IKDLEV 108
Query: 1189 FLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKL 1248
+ N+S +++C W +++ E+++ +W RG+ + + +AHGEG+ LDK
Sbjct: 109 TFEANTSNQYQCGWQDIEVPESDS---IWMRGI--HEIRLPIAHGEGKLLP-----LDKT 158
Query: 1249 YKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCP- 1307
VA++Y D NGS + +A V + G+ + MPHPER V Q
Sbjct: 159 NLKVSVAMRYKQD-----------VNGSYNRIAAVTAYGGKMLITMPHPERAVSLVQTDD 207
Query: 1308 --APCPTVTNPSVRNSQASPWLRLFQNAYSW 1336
+ + P +R+F+NAY +
Sbjct: 208 YYLVREEYRRRYLPTPKDGPGMRIFKNAYDY 238
>UniRef50_A0LFD0 Cluster: Phosphoribosylformylglycinamidine
synthase; n=2; Deltaproteobacteria|Rep:
Phosphoribosylformylglycinamidine synthase -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 1009
Score = 83.8 bits (198), Expect = 3e-14
Identities = 172/779 (22%), Positives = 286/779 (36%), Gaps = 87/779 (11%)
Query: 190 MRKVNDKLGLAFDTWDMEFYMDLF----VNKLKRD-----PTSVELFDLAQSNSEHSRHW 240
+ +++D+ LA + D+ +D F V + +R+ PT VEL ++Q+ S+H H
Sbjct: 190 LMRLSDERNLALNPLDVPVILDYFARPEVVRARREMGLGAPTDVELEAISQARSDHCNHN 249
Query: 241 FFKGKLVLDGKEINESLIDMVASTQKTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRGPS 300
F+GK E + V + KT + A K + ++L +
Sbjct: 250 TFRGKFHYRDLATGERTV--VDNLFKTCIEAPTLAI----QAEKDWVVSVLWDN-----A 298
Query: 301 QVIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVG 360
V + ++ + T ETHN P+ + + GA TG G RD+ G G+G AG GY VG
Sbjct: 299 GVARFDDNNNYVITGETHNSPSNMEAYGGALTGIVGIYRDIMGTGKGARLTAGLYGYCVG 358
Query: 361 NLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNA 420
P + +G P P +++ G D GNK G P G N
Sbjct: 359 ---------PKDYRGPLRP--HLHPRRLLDGIVEGVKDGGNKHGVPTPFG--------NL 399
Query: 421 DNTREEFVKPIMFSGGIGYMPHSMIKK----NKPDKGMLLVKXXXXXXXXXXXXXXXXXX 476
K ++F +G MP + + +PD G ++
Sbjct: 400 FFHPSFLGKCLVFVAALGIMPRLVRGEPSDLKRPDPGDFII------MSGGRVGKDGIHG 453
Query: 477 XXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLES-DVNPVESIHDQGAGGNGNVLK 535
+ + G VQ GD +++ + LE+ D + I D G GG + +
Sbjct: 454 VTASSEIYSESTPAGHVQIGDPYTQKKMHDFL---LEARDEGLISFITDNGGGGLSSSVG 510
Query: 536 ELVE-PEGAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPV 594
E GA V + L + E+W +E QE + + + E+ RR
Sbjct: 511 ESARFCGGARVELDKVPLKYEGLDQWEIWVSESQERMTVAVNPRHLDRFMELSRRHEVES 570
Query: 595 SFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQT 654
+ +G DG + L T LD S L E+ + ++ + P L
Sbjct: 571 TAIGTYGSDGRLHLTYRGKTCACLDLS--LFTEAFPQWEFEADWQ------PPDNRGLH- 621
Query: 655 EKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPL 714
+ L+ P D L VL NV S+ ++ + D V G + G
Sbjct: 622 ----EPVLAEPAD--YGRLLHDVLARPNVCSREWIQRQYDHEVQGGSVIKLMTGVDRDVP 675
Query: 715 ADCAIIALSYYDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCS 774
D A++ + G A S +D ++ EA+ LV G LE++
Sbjct: 676 NDAAVLRPALESRRGLAVSQSINPTYSAIDTYHMVAATIDEAVRRLVAVG-GRLEEIGGV 734
Query: 775 GNWMWAG-----KTGVEXXXXXXXXXXXXXXMR----ALGVAVDGGKDSLSMCAHVAG-- 823
N+ W + + +R A G+ + GKDS+ + H+ G
Sbjct: 735 DNFCWPSVQYDPVSNPDGRYKAAQLVRANWALRDICLAFGIPLLSGKDSMYVDGHLGGAY 794
Query: 824 ---EKVKSPGTLVVSTYAPCPDITVKIEPALKEENSALVHAPVSPGKYRLGGSALAQCYK 880
K+ T+ + PDI+ +K LV+ + LGGS C+
Sbjct: 795 GERHKISGLPTMQFTATTVVPDISDCQTMDVKTAGD-LVYV-LGWTHDELGGSEYYDCFG 852
Query: 881 QLGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNL 939
LG N ++++ +K ++E + S H I GG + G G+ L
Sbjct: 853 YLGRNVPELDPESVL-PVYRVVEKAIREGLVASCHGIYRGGLGVHAAMAAMAGGLGMRL 910
>UniRef50_A1UT45 Cluster: Phosphoribosylformylglycinamidine synthase
I; n=1; Bartonella bacilliformis KC583|Rep:
Phosphoribosylformylglycinamidine synthase I - Bartonella
bacilliformis (strain ATCC 35685 / KC583)
Length = 222
Score = 83.0 bits (196), Expect = 5e-14
Identities = 69/236 (29%), Positives = 113/236 (47%), Gaps = 36/236 (15%)
Query: 1067 IKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADT 1126
+K A+++ G+N DR+MIA+L + + V + + T+ +V PGGFSY D
Sbjct: 1 MKTAIIQLPGLNRDRDMIAAL----YHITGVEPLKIWQTEATIPDVDMIVIPGGFSYGDY 56
Query: 1127 LGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKA 1186
L G + + + Q K +K +G+CNG Q++ + P +
Sbjct: 57 L------RCGAIGARTPVLQAVREKAQKGVTVIGICNGFQILLEAKLL-PGT-------- 101
Query: 1187 QIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMG-GSVLGVWVAHGEGRFTVADGSLL 1245
L N+S +F CR VK+ E N + ++ RG G ++ VAH +G + AD L
Sbjct: 102 ---LMRNTSLKFVCR--EVKL-EVVNADTIFSRGYSKGKIIRCPVAHHDGNY-FADSDTL 154
Query: 1246 DKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCV 1301
K+ N Q+ +Y ++ NPNGS + +AG+ + G + MMPHPE +
Sbjct: 155 KKMEDNKQIVFRYAENT---------NPNGSINNIAGIVNEAGNVLGMMPHPENFI 201
>UniRef50_O41977 Cluster: Tegument protein/FGARAT; n=1; Murid
herpesvirus 4|Rep: Tegument protein/FGARAT - Murid
herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68)
Length = 1275
Score = 82.2 bits (194), Expect = 9e-14
Identities = 147/632 (23%), Positives = 233/632 (36%), Gaps = 47/632 (7%)
Query: 731 ATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELED--VKCSGNWMWAGKTGVEXX 788
A++IG Q+ K DP G+ L EAL NL + LE + CS A E
Sbjct: 664 ASAIGEQHYKVKEDPILGSTYGLVEALLNLNTCPGATLEKTIITCSVTCSQADVAHSELY 723
Query: 789 XXXXXXXXXXXXMRALGVAVDGGKDSLSMCAHVAGEKVKSPGTLVVSTYAPCPDITVK-- 846
M + K+ + C + SP L+V + D +
Sbjct: 724 DAIAECKNMCTMMGCTFMCDMAAKNPRN-C------DINSP--LIVFSAKCIVDFPWRGR 774
Query: 847 IEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLL 906
I P LKE ++ L+ P+ + L GS + + L TQKL
Sbjct: 775 IGPNLKEHHNTLLWLPIH-SQPTLAGSIFKTFNPHVPIHRLPQISVNALFKLLTNTQKLF 833
Query: 907 KEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANV-SPIEALFNEELGIVLEVS 965
++ K+ S HD+S+GG +T V EM + G G ++ + + ++ +P L +E G V+EV
Sbjct: 834 EQDKIRSIHDVSDGGLLTCVAEMAMSG--GKSVVMTLPDHIANPKAMLLSETPGYVIEVD 891
Query: 966 KNDLPYVLSEYNNNGVGAQHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFRMW-----E 1020
+ +L+ N A IG S + N+L +V W +
Sbjct: 892 NDSTDAILTFLQENSCVAMPIGRVVPLTESSTFSVFHKSENLLSVPFFNVVGCWRRRHVD 951
Query: 1021 ETSYRLECLQANTDCVLQEWKVLE-KRKGATYNVTFDPTAAVIKTKSI--KVAVLREEGI 1077
E++ L E+ + G + P + +V V+ G
Sbjct: 952 ESTLLCTHLGPRRSIYAIEYGHNQFNFPGVSRYFLTSPVRSFRAPPHAQKRVCVIEFNGQ 1011
Query: 1078 NGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGI 1137
+ L A F V S L + + +LD F G+VF G G A
Sbjct: 1012 TSLEGTLFMLQYAGFLPEIVHSSCLHDFETSLDRFCGIVFTGSMCTLHEHGGVLAAATRF 1071
Query: 1138 LFSESLSSQFAHFKDRKDTFSLGVCN-GCQLMAMLGWVDPDSNS-----KGSNKAQIFLD 1191
S ++ S+ + F R DTF LG G Q++ L ++ ++ K + L
Sbjct: 1072 TESHTVVSKLSAFCRRPDTFMLGFDQLGMQILLNLNILNITADKTMYDCKIDPLECMPLK 1131
Query: 1192 HNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLYKN 1251
N+S +E RW I E+ + ++F+ + +V W+ G D
Sbjct: 1132 KNASCTYESRWLNFYIPESNS---LFFKPIQQNVFPSWI-QGSNLGLPLDQHQESFWRNT 1187
Query: 1252 GQVAVQYVDDDGKPTEV---YPMNP-NGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCP 1307
Q+ Y + P YP NP GSP +AG+ S DGR + P W
Sbjct: 1188 RQICTYYQTEQPTPGIAAINYPRNPVAGSP--VAGICSLDGRITGCLIDPAESFFPWTWQ 1245
Query: 1308 APCPTVTNPSVRNSQASPWLRLFQNAYSWAIN 1339
P R ++PW FQ W ++
Sbjct: 1246 FV------PGNRALASTPWQLCFQQLLIWTLS 1271
>UniRef50_Q5ZUW6 Cluster: Phosphoribosylformylglycinamidine synthase
I; n=4; Legionella pneumophila|Rep:
Phosphoribosylformylglycinamidine synthase I - Legionella
pneumophila subsp. pneumophila (strain Philadelphia 1
/ATCC 33152 / DSM 7513)
Length = 420
Score = 82.2 bits (194), Expect = 9e-14
Identities = 68/238 (28%), Positives = 111/238 (46%), Gaps = 16/238 (6%)
Query: 1067 IKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADT 1126
+K+AV++ G N +RE + ++ A + +D K +D G + GGFSY D
Sbjct: 2 MKIAVVQFPGSNCERETMLAVQRAGMTPVEFLWNDSSQKLREMD---GYIIIGGFSYEDR 58
Query: 1127 LGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSK-G--- 1182
AGI+ + + + LG+CNG Q++ G V N + G
Sbjct: 59 S------RAGIIAALDPVMKEIKLQSELGKPVLGICNGAQILVETGLVPGLKNYQIGMAL 112
Query: 1183 SNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMG-GSVLGVWVAHGEGRFTVAD 1241
+ +I F W ++ + +++ + R + SVL + AH EGRF V
Sbjct: 113 TENKRIQDGKILGTGFYNSWIHMRTGDRV-RQNAFTRYLSKDSVLSIPAAHAEGRF-VMP 170
Query: 1242 GSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPER 1299
LL ++ + G A QY D G + +P+NPNGS +A + ++ G +A+MPHPER
Sbjct: 171 VKLLQEIEEEGLNAFQYCDAQGNRDDNFPVNPNGSLRNIAAIINKAGNVMAIMPHPER 228
>UniRef50_A5BZD1 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 283
Score = 82.2 bits (194), Expect = 9e-14
Identities = 36/80 (45%), Positives = 54/80 (67%)
Query: 353 GTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFV 412
G AGY VG+L+I G+ PW + + Y SN A+ LQI+++ S+GASD N+FGEP+I +
Sbjct: 194 GEAGYCVGSLNIEGFYAPWGDPSFTYLSNLASSLQILVDDSSGASDCRNEFGEPLIQSYA 253
Query: 413 QSYGLKNADNTREEFVKPIM 432
++ G+K R E++ PIM
Sbjct: 254 RTIGMKLLSEERREWLMPIM 273
>UniRef50_A6G366 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=1; Plesiocystis pacifica SIR-1|Rep:
Phosphoribosylformylglycinamidine synthase II -
Plesiocystis pacifica SIR-1
Length = 1010
Score = 80.6 bits (190), Expect = 3e-13
Identities = 103/432 (23%), Positives = 165/432 (38%), Gaps = 26/432 (6%)
Query: 180 VPLQEQGISAMRKVNDKLGLAFDTWDMEFYMDLFVNKLKRDPTSVELFDLAQSNSEHSRH 239
V L+E + + +++ + LA +M+ F L RDPT EL LAQ+ SEH +H
Sbjct: 178 VALREADDATLERISKEGMLALTLAEMQAIAAHF-RGLGRDPTDAELECLAQTWSEHCKH 236
Query: 240 WFFKGKLVLDGKEINESLIDMVASTQKTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRGP 299
F + + +E+LI+ + S L +V
Sbjct: 237 KIFASPIRYVDPQGDETLIERGLFRSYVRAATEAVADARKQSGADPEGEDFL--VSVFHD 294
Query: 300 SQVIQKKTESD-IIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYS 358
+ + + TE+D +++ ETHN P+A+ P+ GA TG G RD G G G ++ GY
Sbjct: 295 NAGVVRFTEADHLVYKVETHNSPSALDPYGGAMTGIVGVNRDSFGTGLGADLLSNVWGYC 354
Query: 359 VGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLK 418
G+ P D G P P +I +G D GN+ G P GF + + +
Sbjct: 355 FGDPRGPLRD----RSG--LPPGLMHPRRIRDGVHHGVIDGGNQSGIPYSRGF-ELFDGR 407
Query: 419 NADNTREEFVKPIMFSGGIGYMPHSM-----IKKNKPDKGMLLVKXXXXXXXXXXXXXXX 473
A KP+++ G + MP ++ + +P + +
Sbjct: 408 YAG-------KPLVYCGTVAAMPVTVPGPPPERAPRPTEDKPIAVGDRVVMVGGRIGKDG 460
Query: 474 XXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLESDVNPVESIHDQGAGGNGNV 533
D + AVQ GD + + D + D GAGG +
Sbjct: 461 IHGATFSSVELDESSPVQAVQIGDPITQKMMWDFLSEA--RDRGLYSGMTDNGAGGLSSS 518
Query: 534 LKELVE-PEGAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERC 592
+ E+ E GA + + L P + E+ +E QE + A E+ R
Sbjct: 519 VGEMAEATNGARIDLAKAPLKYPGLAPWEILISEAQERMTVAVPPAQLDAFLELAARREV 578
Query: 593 PVSFVGEVTGDG 604
S +GE T DG
Sbjct: 579 EASVLGEFTDDG 590
Score = 35.5 bits (78), Expect = 9.9
Identities = 17/41 (41%), Positives = 23/41 (56%)
Query: 803 ALGVAVDGGKDSLSMCAHVAGEKVKSPGTLVVSTYAPCPDI 843
A GV + GKDS+ A + G K+ P TL+VS PD+
Sbjct: 784 AYGVPLISGKDSMKNDAFLGGVKISIPPTLLVSVMGQTPDV 824
>UniRef50_Q2NF29 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=2; Methanobacteriaceae|Rep:
Phosphoribosylformylglycinamidine synthase 1 -
Methanosphaera stadtmanae (strain DSM 3091)
Length = 221
Score = 79.8 bits (188), Expect = 5e-13
Identities = 71/237 (29%), Positives = 111/237 (46%), Gaps = 42/237 (17%)
Query: 1067 IKVAVLREEGINGDR--EMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYA 1124
+ V ++R G N DR E +L+ AN +DL + V+ PGGFSY
Sbjct: 7 VNVGIIRFPGTNCDRDIEYAVNLVGANSHYIYWNETDLSQMDV-------VIIPGGFSYG 59
Query: 1125 DTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSN 1184
D L + G AGI FA +K+ LG+CNG Q++ + V
Sbjct: 60 DYLRA--GSIAGITPIIDAIKDFA----KKENPVLGICNGAQILGEIDLVPG-------- 105
Query: 1185 KAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSL 1244
+F++ N + +F C+ +K++ ++ V+ + +AH EGR+ +
Sbjct: 106 ---VFIE-NENAKFICKSKKLKVNTTRTPFTKLYKK--NEVIDLPIAHKEGRYYTDN--- 156
Query: 1245 LDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCV 1301
L+ LY N Q+ + + +DG NPNGS D + GV + DG +A+MPHPER V
Sbjct: 157 LETLYDNNQIVLTF--EDG--------NPNGSLDNITGVCNVDGNVVAVMPHPERAV 203
>UniRef50_Q8ZZJ7 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=4; Pyrobaculum|Rep:
Phosphoribosylformylglycinamidine synthase II -
Pyrobaculum aerophilum
Length = 697
Score = 79.0 bits (186), Expect = 8e-13
Identities = 87/322 (27%), Positives = 127/322 (39%), Gaps = 43/322 (13%)
Query: 293 PTNVRGP---SQVIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGH 349
P VRGP + +++ F E+HN P+AV P++GA TG GG IRD+ VG
Sbjct: 52 PWVVRGPGTDAPLVEIAEGLYATFKIESHNHPSAVDPYNGAATGVGGIIRDILTVG--AR 109
Query: 350 TVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVIS 409
+A + NLH P W I + G SDYGN+ G PV+
Sbjct: 110 PIA-----LLVNLHFGPPSHPHAR--W-----------IAVNVIRGISDYGNRVGVPVVG 151
Query: 410 GFVQSYGLKNADNTREEFV-KPIMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXX 468
G + E+F PI+ + +G + + + G L++
Sbjct: 152 GETWFH---------EDFTYTPIVLATCVGIVEKDGVPPGGAEPGDLII-VAGLGADKSG 201
Query: 469 XXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLESDVNPVESIHDQGAG 528
+A + D GAVQ D MG +L +VR V+ I D G G
Sbjct: 202 LGGSAFASKTLSEEAEE---DLGAVQVADPLMGKKLIDLVREARSC----VKFIKDLGGG 254
Query: 529 GNGNVLKELVE--PEGAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEI 586
G L EL E G V + + D + E+ +E QE + S + LE +
Sbjct: 255 GLATALAELAEWFQLGVVAELDKIHMADREMGPAEVLTSETQERMVFVTSPSKLECLERL 314
Query: 587 CRRERCPVSFVGEVTGDGYMSL 608
+ P S VG T +G + L
Sbjct: 315 LEKFEVPYSIVGRFTAEGRVVL 336
>UniRef50_O67691 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=2; Aquifex aeolicus|Rep:
Phosphoribosylformylglycinamidine synthase II - Aquifex
aeolicus
Length = 745
Score = 79.0 bits (186), Expect = 8e-13
Identities = 157/747 (21%), Positives = 276/747 (36%), Gaps = 83/747 (11%)
Query: 296 VRGPSQ---VIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVA 352
V+GP + V++ + + F E+HN P+ + PF GA TG GG IRDV +G +A
Sbjct: 62 VQGPGENAGVVKIDEKVWVAFKVESHNHPSYIEPFHGAATGVGGIIRDVLSMGARPIALA 121
Query: 353 GTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISG-- 410
+ + N H E K +++ +G S YGN G P ++G
Sbjct: 122 DSLRFGEFNYH--------ETK------------RLVKGVVSGISFYGNCIGVPTVAGET 161
Query: 411 -FVQSYGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXX 469
F SY P++ + +G +P + + + + L+
Sbjct: 162 VFEPSYK-----------TNPLVNAFCLGVIPAGRMYRARATREGQLLFLIGSSTGRDGI 210
Query: 470 XXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLESDVNPVESIHDQGAGG 529
D + + VQ GD G +L + +E D+ + + D GA G
Sbjct: 211 FGAVMASGEFSEDVEEKRPN---VQIGDPYFGKKLVEAIMEIVEKDL--IVGMQDLGAAG 265
Query: 530 NGNVLKELV--EPEGAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEIC 587
E+ +G ++ + L + + E+ +E QE L+ + N ++EI
Sbjct: 266 LAGSASEIAAKSEKGVELYLENVPLREKDMNPYEILLSESQERMLLVVEEENVEKVKEIA 325
Query: 588 RRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHL-EAVLGNMP 646
+ + VG++T D D++ + K E ++LP L + EA + + P
Sbjct: 326 NKWHLEGAVVGKITDD-------DTFRAYY-------KGELVAELPVSLIVDEAPVYDRP 371
Query: 647 RKTFDLQTEKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQC 706
K + E R P+ VK AL ++L N++ K ++ + D Q
Sbjct: 372 YKEPEYMKEVRNFNQEELPQ-TDVKEALKKLLSSPNISCKEWVYTQYD--------YQVG 422
Query: 707 VGPLHTPLADCAIIALSYY---DLV---GSATSIGTQNIKGLLDPAAGARLSLGEALTNL 760
L P D A++ L + +L G A S L+P G + + E NL
Sbjct: 423 TNTLLIPGHDAAVLRLKWVLRPELTTEKGIAISSEGNGRMVYLNPYEGGKFVVAEVCRNL 482
Query: 761 VFAGISELEDVKCSGNWMWAGKTGVEXXXXXXXXXXXXXXMRALGVAVDGGKDSLSMCAH 820
G L C N+ + + LG+ V G SL
Sbjct: 483 ACVGAKPLAITDCL-NFGNPERPEI-MWQFVKAVEGMAEACEELGIPVVSGNVSL-YNET 539
Query: 821 VAGEKVKSPGTLVVSTYAPCPDITVKIEPALKEENSALVHAPVSPGKYRLGGSALAQCYK 880
V ++++ + + K P+ E+ S L RL GS +
Sbjct: 540 VEKNEIRNVFPTPIVVGVGVLEKAEKYTPSKVEKESELYLVGNLEENLRLDGSEYLKVIH 599
Query: 881 QLGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLH 940
L K L + ++ + HD+S GG + +LEM G L
Sbjct: 600 GLIKGDVPPVDLEKEKILINLLISFNNKELITCAHDVSVGGLLIALLEMVFRTPYG--LE 657
Query: 941 VNVAANVSPIEALFNEE-LGIVLEVSKNDLPYVLSEYNNNGVGAQHIGYTGKYGMDSQVV 999
V V + P F+E +++ V + V + G+ +IG T + + ++
Sbjct: 658 VEVYTDERPDVFFFSENPTRVIIGVESDKAEEVKNAVEKAGLEWMYIGKTTE---EKKIK 714
Query: 1000 INLNGVNVLDTVLIDVFRMWEETSYRL 1026
+ NG +L+ L + ++W + +L
Sbjct: 715 VTFNGDTLLEDELEEYEKLWRTSLEKL 741
>UniRef50_A5EXN9 Cluster: Phosphoribosylformylglycinamidine synthase;
n=1; Dichelobacter nodosus VCS1703A|Rep:
Phosphoribosylformylglycinamidine synthase -
Dichelobacter nodosus (strain VCS1703A)
Length = 1235
Score = 78.2 bits (184), Expect = 1e-12
Identities = 64/218 (29%), Positives = 96/218 (44%), Gaps = 9/218 (4%)
Query: 1084 IASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILFSESL 1143
++ +++ N D+ S +Q TL+ Q + GGFS D + + A L +
Sbjct: 999 VSEVVICNRHQKDIDDS-VQRFVRTLENSQILALSGGFSVGDEPDGSGKFIANTLRQPQI 1057
Query: 1144 SSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQIFLDHNSSERFECRWS 1203
+ F R D LG+CNG Q + G + P + L HN +R R
Sbjct: 1058 ADAIEAFLQR-DGLILGICNGFQALIKCGLL-PYGKLQQRAPNDPTLTHNHIQRHIARIV 1115
Query: 1204 AVKIHENENKEDVWFRGMG-GSVLGVWVAHGEGRFTVADGSLLDKLYKNGQVAVQYVDDD 1262
I N + W + GS + ++HGEG F A+ S+L L NGQ+A QY + D
Sbjct: 1116 TTVISNNHSP---WLQDFKVGSCHDIAISHGEGLFW-AESSVLQTLSANGQIATQYANPD 1171
Query: 1263 GKPTEVYPM-NPNGSPDGLAGVRSRDGRHIAMMPHPER 1299
+ P+ NPNGS + + S GR + M H ER
Sbjct: 1172 TGKASLLPIYNPNGSHWAIEAITSPCGRILGKMGHSER 1209
Score = 45.6 bits (103), Expect = 0.009
Identities = 67/294 (22%), Positives = 113/294 (38%), Gaps = 26/294 (8%)
Query: 313 FTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWE 372
F ETHN PT + PF GA+T GG IRD ++G A Y L + G P E
Sbjct: 316 FKNETHNHPTEIEPFGGASTCIGGAIRD---------PLSGRA-YVYQALRLSGCADPRE 365
Query: 373 EKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKPIM 432
+ + + I A+ GAS YGN+ G + +G Q + +A K +
Sbjct: 366 AIA-DTLTGKLPQIVIAQRAAAGASSYGNQIG--LATG--QVVEIYHAGYK----AKHLE 416
Query: 433 FSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGA 492
+ P +++ P G ++V A +
Sbjct: 417 VGAVVAAAPAEHVRRETPKAGDIVVLLGGATGRDGCGGATGSSREHNRDSLTQSAAE--- 473
Query: 493 VQRGDAEMGNRLNRVVRGCLESDVNPVESIHDQGAGGNGNVLKELVEPEGAVVFTKEFQL 552
VQ+G+A +L R+ R + V+ +D GAGG + E+ + +
Sbjct: 474 VQKGNAPEERKLQRLFRQA--AFAQKVKRCNDFGAGGVCVAVGEIA--SSLDINLDAVPV 529
Query: 553 GDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGEVTGDGYM 606
++ EL +E QE A++ + + + ++ +E + +VT G M
Sbjct: 530 KYQGLSATELAISESQERMAIVIAAEDFAAISDLAAKENLSACKIAQVTDSGKM 583
>UniRef50_O59619 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=15; cellular organisms|Rep:
Phosphoribosylformylglycinamidine synthase 1 - Pyrococcus
horikoshii
Length = 223
Score = 77.8 bits (183), Expect = 2e-12
Identities = 68/233 (29%), Positives = 104/233 (44%), Gaps = 35/233 (15%)
Query: 1067 IKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADT 1126
+K AV+ G N D E + ++ A + V K ++ + GVV PGGFSYAD
Sbjct: 2 VKFAVIVFPGTNCDFETVEAIKRAGGEAERVWY------KQSVKDYDGVVIPGGFSYADY 55
Query: 1127 LGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKA 1186
L A I + + + + LG+CNG Q++ +N
Sbjct: 56 LR-----AGAIAARQKVMEEIRELAEEGRPI-LGICNGFQILT------------EANLL 97
Query: 1187 QIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLD 1246
L N RF C+W +K+ + E + G V+ + +AH EG + + + S +
Sbjct: 98 PGALRPNKIPRFLCKWVHLKVVDVETPFTYLYE--EGEVVRMPIAHAEGNYYIDNPSKV- 154
Query: 1247 KLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPER 1299
++ QY D+ G TE NPNGS +AGV ++ G + MMPHPER
Sbjct: 155 ------RIVFQYSDEKGSITE--EANPNGSVLNIAGVTNKQGNVLGMMPHPER 199
>UniRef50_Q67KF7 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=6; Bacteria|Rep: Phosphoribosylformylglycinamidine
synthase 1 - Symbiobacterium thermophilum
Length = 235
Score = 77.0 bits (181), Expect = 3e-12
Identities = 60/191 (31%), Positives = 86/191 (45%), Gaps = 23/191 (12%)
Query: 1109 LDAFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLM 1168
L + VV PGGF+Y D + S + + A F R LG+CNG Q++
Sbjct: 39 LTPYDAVVIPGGFTYGDRVRSG-----ALACRAPVMEAVAEFAARGGLV-LGICNGFQIL 92
Query: 1169 AMLGWVDPDSNSKGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGV 1228
G + G + N+ R+ C WS V++ + R G VL +
Sbjct: 93 TEAGLLP------GGFRP------NAHGRYRCGWSRVRVENAATPFTLACRP--GQVLKI 138
Query: 1229 WVAHGEGRFTVADGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDG 1288
V+HG G + AD L L +N QV +Y +G T NPNGS + +AG+ +R G
Sbjct: 139 PVSHGMGNYQ-ADPDTLRALSENQQVLFRYCTPEGAVTP--GANPNGSAENIAGIVNRTG 195
Query: 1289 RHIAMMPHPER 1299
+MPHPER
Sbjct: 196 NVAGVMPHPER 206
>UniRef50_Q01000 Cluster: Probable membrane antigen 3; n=4;
Herpesviridae|Rep: Probable membrane antigen 3 -
Saimiriine herpesvirus 2 (strain 11) (SaHV-2)
(Herpesvirus saimiri)
Length = 1246
Score = 76.6 bits (180), Expect = 4e-12
Identities = 46/148 (31%), Positives = 75/148 (50%), Gaps = 11/148 (7%)
Query: 1193 NSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLYKNG 1252
NSS +FE RWS + I E+ + F+ + S++ W +F +L+K+ ++G
Sbjct: 1087 NSSRKFESRWSNIYIPESTKA--IAFQSLKNSLIPCWTQGTHLKF-YHPKPMLEKMEESG 1143
Query: 1253 QVAVQYVDDD--GKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCPAPC 1310
V+ + P + YP+ PNG + +AGV S DGRH+A++ P C WQ P
Sbjct: 1144 MVSSMFYGHSLSSGPAQNYPLTPNGE-NAIAGVCSADGRHLALLHDPSLCNNLWQW--PY 1200
Query: 1311 PTVTNPSVRNSQASPWLRLFQNAYSWAI 1338
+ NP ++ SPW +F + + W I
Sbjct: 1201 VPLENPPLK---VSPWKTMFLDLHKWGI 1225
Score = 69.7 bits (163), Expect = 5e-10
Identities = 47/177 (26%), Positives = 84/177 (47%), Gaps = 6/177 (3%)
Query: 813 DSLSMCAHVAGEKVKSPGTLVVSTYAPCPDITVKIEPALKEENSALVHAPVSPGKYRLGG 872
++L + + ++V S D++ I P LK NS L Y L G
Sbjct: 725 EALRVSCTFTANATEGGASIVASAIVNTLDVSKCITPDLKFNNSFLFLLTTEKD-YSLFG 783
Query: 873 SALAQCYKQ--LGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMG 930
S Q ++ +G+ K + + Q L+K++ ++SGHD+S+GG + TV EM
Sbjct: 784 SVAQQILEKTFIGE-IPSATSPVMLKKMLSVLQTLIKDESVVSGHDVSDGGLVATVAEMA 842
Query: 931 IGGVRGLNLHVNVAANVSPIEALFNEELGIVLEVSKNDLPYVLSEYNNNGVGAQHIG 987
+ G +G+ ++V + I+ L +E G+V+EV + + YV ++ + Q IG
Sbjct: 843 LSGGKGVRVYVPHGEDA--IKFLCSETPGVVIEVQGSKMYYVQQFLHSENINFQIIG 897
>UniRef50_Q9HJA4 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=4; Thermoplasmatales|Rep:
Phosphoribosylformylglycinamidine synthase II -
Thermoplasma acidophilum
Length = 759
Score = 75.8 bits (178), Expect = 8e-12
Identities = 107/471 (22%), Positives = 189/471 (40%), Gaps = 59/471 (12%)
Query: 302 VIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGN 361
V+ E + E+HN P+AV P+ GA TG GG +RDV + G VA +G+
Sbjct: 93 VVDFDGEYAYVLKMESHNHPSAVEPYGGAATGIGGIVRDV--LCMGAQPVALIDSLFLGD 150
Query: 362 LHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNAD 421
+ Y+ +P I G DYGN+ G P ++G + L N++
Sbjct: 151 VSSDRYE------------GLLSPRYIFGGVVGGIRDYGNRIGIPNVAGSLYFDKLYNSN 198
Query: 422 NTREEFVKPIMFSGGIGYMPHSMIKKNKPDK-GMLLVKXXXXXXXXXXXXXXXXXXXXXX 480
P++ +G +G + I ++K K G +LV
Sbjct: 199 --------PLVNAGCVGIVRRDRIVRSKSYKPGDVLVLMGGKTGRDGIHGVNFASTTLGK 250
Query: 481 XDARDHALDFGAVQRGDAEMGNRLNRVVRGCLE-SDVNPVESIHDQGAGGNGNVLKELVE 539
A+Q G+ + + ++ LE +D + ++ D G GG + E+V
Sbjct: 251 VTKSSRL----AIQLGNPIVEQPM---IKAVLEANDAGLIRAMKDLGGGGLSSAATEMVY 303
Query: 540 PE--GAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFV 597
GA + + +L + ++ E+W +E QE + C + + +I + S +
Sbjct: 304 AGGFGAEITLDDIKLKESNMSGWEIWISESQERMLMECYPEDVEKIRQIAEKWNLDFSVI 363
Query: 598 GEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMP--RKTFDL-QT 654
G+VT D R+++ K + D+ +E L + P ++ + + +
Sbjct: 364 GQVTAD------------------RRIRVYYKKRKIIDMDIE-FLDDSPVYQRPYRIKEV 404
Query: 655 EKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVG-PLHTP 713
EK +P P+D+ D + RL N ++ + + D V G VG P
Sbjct: 405 EKSVTVPQE-PEDLN-SFVRDFMARL-NTCARFNVVRQYDHTVRGSTIVTPFVGRPNKET 461
Query: 714 LADCAIIALSYYDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAG 764
AD +I + G + G++ +DP AG L+L EA N++ G
Sbjct: 462 HADATVIKPLENSMRGLVLTSGSRPNMVSVDPYAGTLLTLAEAYKNILSTG 512
Score = 56.8 bits (131), Expect = 4e-06
Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 7/115 (6%)
Query: 907 KEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNE-ELGIVLEVS 965
K ++S HD+S GG + EM G G ++ ++ + P LF+E G+VLE++
Sbjct: 644 KADMILSSHDVSSGGLFAALSEMSFGSGIGFHVDISNVSAARPTVKLFSECGNGLVLEIA 703
Query: 966 KNDLPYVLSEYNNNGVGAQHIGYTGKYGMDSQVVINLNGVNVLDTVLIDVFRMWE 1020
K+ + +NG+ + +G TG +++++ G+N++D + D+ WE
Sbjct: 704 KDKEEQFVD--GSNGLAIKRLGETG----GDRIIVDEAGLNIIDVAVDDLRGAWE 752
>UniRef50_Q6N376 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=19; Bacteria|Rep: Phosphoribosylformylglycinamidine
synthase 1 - Rhodopseudomonas palustris
Length = 233
Score = 73.7 bits (173), Expect = 3e-11
Identities = 74/236 (31%), Positives = 111/236 (47%), Gaps = 28/236 (11%)
Query: 1067 IKVAVLREEGINGDREMIASLMLANF-DVFDVTMSDLQNKKITLDAFQGVVFPGGFSYAD 1125
+K AVL GIN +R+M +L L + D V ++ + K T VV PGGFSY D
Sbjct: 1 MKSAVLVFPGINRERDMARALKLVSGNDAAMVWHAETELPKGT----DLVVVPGGFSYGD 56
Query: 1126 TLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNK 1185
L AA +++ +FA LGVCNG Q++ G +
Sbjct: 57 YLRCG-AIAARAPVMDAVR-KFA----ADGGLVLGVCNGFQILCESGLLPG--------- 101
Query: 1186 AQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLL 1245
L N+ +F CR +++ N+ ++ G V+ V VAHGEG + AD +
Sbjct: 102 ---VLMRNARLKFICRDVHLRVERNDTPFTQGYKA--GQVIKVPVAHGEGNYE-ADEDTV 155
Query: 1246 DKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCV 1301
+L +G+V +Y +G+ E + N NG+ +AG+ S G + MMPHPE V
Sbjct: 156 KRLEGDGRVLYRYCSPEGEVGESH--NINGAAASIAGIVSERGNVLGMMPHPENHV 209
>UniRef50_Q7NL01 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=19; cellular organisms|Rep:
Phosphoribosylformylglycinamidine synthase 1 -
Gloeobacter violaceus
Length = 232
Score = 73.7 bits (173), Expect = 3e-11
Identities = 71/234 (30%), Positives = 107/234 (45%), Gaps = 29/234 (12%)
Query: 1067 IKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADT 1126
+K AV+ G N DR+++ + D + + + LD V PGGFSY D
Sbjct: 1 MKFAVIVFPGSNCDRDVVT----VTRGLLDQPTRLVWHTEDDLDGCDVAVIPGGFSYGDY 56
Query: 1127 LGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKA 1186
L A FS + + H + + +G+CNG Q++ G + P +
Sbjct: 57 LRCG----AIARFSPVMQAVRRHAE--RGGLVIGICNGFQVLTEAGLL-PGA-------- 101
Query: 1187 QIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMG-GSVLGVWVAHGEGRFTVADGSLL 1245
L N +F C A+K+ E + W G V+ + +AHGEG + A+ + L
Sbjct: 102 ---LVRNRDLQFVCDRVALKV---ERTDLPWVHSYRPGEVITLPIAHGEGCY-YAEEATL 154
Query: 1246 DKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPER 1299
+L +N QV +Y DG V NPNGS +AG+ +R G + MMPHPER
Sbjct: 155 AELEENRQVVFRYCRPDGTIDAVG--NPNGSLHNIAGLCNRHGNVLGMMPHPER 206
>UniRef50_Q4FLJ5 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=2; Candidatus Pelagibacter ubique|Rep:
Phosphoribosylformylglycinamidine synthase 1 -
Pelagibacter ubique
Length = 227
Score = 73.3 bits (172), Expect = 4e-11
Identities = 67/232 (28%), Positives = 105/232 (45%), Gaps = 29/232 (12%)
Query: 1070 AVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLGS 1129
+V+ G N DR+M +L F V D++ K L VV PGGFSY D L
Sbjct: 4 SVITFPGSNCDRDMDVALKKFGFKNKMVWHDDVELPKSDL-----VVLPGGFSYGDYLRC 58
Query: 1130 AKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQIF 1189
+ + L+ FA + +GVCNG Q++ G +
Sbjct: 59 GSMASKSKIMKSVLN--FAQGGGKV----MGVCNGFQILVESGLLPG------------V 100
Query: 1190 LDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLY 1249
L N F C+ VK + NK++ +F+ ++ +AH EG + ++ + + +
Sbjct: 101 LLRNKYLEFICKNVFVKAN---NKDNSYFKDDKKNIYEFHIAHNEGNYFCSNDQIKE-IN 156
Query: 1250 KNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCV 1301
N Q+A+ Y D++G E NPNGS +AGV ++ + MMPHPER +
Sbjct: 157 DNNQIALFYSDENGNVNE--QSNPNGSLQNIAGVFNKQKNVLGMMPHPERMI 206
>UniRef50_Q11IV0 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=11; Bacteria|Rep: Phosphoribosylformylglycinamidine
synthase 1 - Mesorhizobium sp. (strain BNC1)
Length = 222
Score = 72.9 bits (171), Expect = 5e-11
Identities = 72/236 (30%), Positives = 114/236 (48%), Gaps = 36/236 (15%)
Query: 1067 IKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADT 1126
+K AV++ G+N DR+MIA+L + VT+ + + +D +V PGGFSY D
Sbjct: 1 MKSAVIQLPGLNRDRDMIAALTKISGQA-PVTVWQTETELPEVDL---IVIPGGFSYGDY 56
Query: 1127 LGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKA 1186
L AA + ++++ + A K +GVCNG Q++ G + P +
Sbjct: 57 LRCG-AIAARMPVMKAVAEKAA-----KGVLVIGVCNGFQILLEAGLL-PGA-------- 101
Query: 1187 QIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMG-GSVLGVWVAHGEGRFTVADGSLL 1245
L N+S +F CR VK+ + N + R G ++ VAH +G F A +L
Sbjct: 102 ---LMRNASLKFVCR--EVKL-QVANANTAFTRAYAPGQIIRCPVAHHDGNFFAAPETLA 155
Query: 1246 DKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCV 1301
++ GQVA +Y + NPNGS + +AG+ + G + +MPHPE V
Sbjct: 156 -RIEGEGQVAFRYAEGT---------NPNGSINDIAGIVNGAGNVLGLMPHPENLV 201
>UniRef50_Q9RXT3 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=126; cellular organisms|Rep:
Phosphoribosylformylglycinamidine synthase 1 -
Deinococcus radiodurans
Length = 221
Score = 71.3 bits (167), Expect = 2e-10
Identities = 70/237 (29%), Positives = 111/237 (46%), Gaps = 39/237 (16%)
Query: 1067 IKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVF-PGGFSYAD 1125
+K AV++ G N D + + + L + D + + + L +VF PGGFSY D
Sbjct: 1 MKTAVIQFPGSNCDADALHAARL----LLDDGAQFVWHTETALPEGTELVFLPGGFSYGD 56
Query: 1126 TLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNK 1185
L S A S +++ AH + + LGVCNG Q++ G + P +
Sbjct: 57 HLRSGAIAAR----SPIMNAVKAHAE--AGGYVLGVCNGFQVLTEAGLL-PGA------- 102
Query: 1186 AQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMG-GSVLGVWVAHGEGRFTVADGSL 1244
L N F C+ +++ EN + R G G ++ + +AHGEG + AD +
Sbjct: 103 ----LSRNKELHFMCKPVHLRV---ENNATDFSRAYGPGQIIEIPIAHGEGNY-YADAAT 154
Query: 1245 LDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCV 1301
+ +L + G+V +Y D NPNGS + +AG+ + G + MMPHPER V
Sbjct: 155 IAELEEGGRVVFRYAD-----------NPNGSLNDIAGIVNERGNVLGMMPHPERAV 200
>UniRef50_Q8TY09 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=1; Methanopyrus kandleri|Rep:
Phosphoribosylformylglycinamidine synthase II -
Methanopyrus kandleri
Length = 724
Score = 70.5 bits (165), Expect = 3e-10
Identities = 164/706 (23%), Positives = 269/706 (38%), Gaps = 76/706 (10%)
Query: 288 HTILRPTNVRGPSQVIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRG 347
H I+ P + + V+ E ++ E+HN P+ V P++GA TG GG +RDV + G
Sbjct: 53 HVIVGPGD---DAAVVAIDDEWAVVVGIESHNHPSYVDPYNGAATGVGGIVRDV--LSMG 107
Query: 348 GHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPV 407
+A G L G +P+ ++ G SDYGN+ G P
Sbjct: 108 AFPIALLDPLRFGPL--DGERVPY----------------LVDGVVRGISDYGNRIGVPT 149
Query: 408 ISGFVQSYGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKNKPDK-GMLLVKXXXXXXXX 466
+ G ++ D + E P++ +G + S I + + D+ G +LV
Sbjct: 150 VGGELE------FDPSYER--NPLVNVMCVGIVRRSEIVRGRADRPGDVLVLVGARTGRD 201
Query: 467 XXXXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLESDVNPVESIHDQG 526
+ D AVQ GD +L +R +E + V+ D G
Sbjct: 202 GIGGAAFASEELGEESEEE---DRPAVQIGDPFTERQLIIAIREAVERGL--VKGCKDLG 256
Query: 527 AGGNGNVLKELVEPEGAVVFTKEFQ--LGDPTITTLELWGAEYQENDALLCSKANRHILE 584
A G E+ G V F+ L + + E+ +E QE L+ + + +
Sbjct: 257 AAGLTCAATEMAADGGTGVEIDVFKVPLREEGMEPWEIMLSESQERMLLVVAPEDVDEVI 316
Query: 585 EICRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGN 644
EICR+ S VG VT DGY+++ + D R+ E + ++ E +
Sbjct: 317 EICRKYGLEASVVGRVTDDGYLTVKDGD------DVIARVPAEFLADGAPEVEWEEEPYS 370
Query: 645 MPRKTFDLQTEKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQ 704
P + +P P+D+ V+S L V+ A + ++ + D V G +
Sbjct: 371 YP---------ENVDVPEPDPEDL-VRSVLSS--PNVSPALREWVYRQYDHEVQG----R 414
Query: 705 QCVGPLHTPLADCAIIALSYYDLVGSATSIGTQNIKG--LLDPAAGARLSLGEALTNLVF 762
V P H D A++ L + L A ++ T + L+DP G + EAL NL
Sbjct: 415 TVVKPGH----DAAVMWLQHEGLEDVALALTTDSNPRHVLIDPKTGTEGCVAEALRNLAT 470
Query: 763 AGISELEDVKCSGNWMWAGKTGVEXXXXXXXXXXXXXXMRALGVAVDGGKDSLSMCAHVA 822
G L V C + + R V V GG SL V
Sbjct: 471 VGAEPLCLVDCLN--FGSPENPRVYYQLRRSIEGLGKAAREFEVPVVGGNVSLYNEHEVD 528
Query: 823 GEKVKSPGTLVVSTYAPCPDITVKIEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQL 882
G +P V ++ P EE A++ + + LGGS Y +
Sbjct: 529 GPVNPTPVIGAVGVIRGLD--YLEDFPREPEEGEAVI--VLGETREELGGSLYLIEYHGI 584
Query: 883 GDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVN 942
++L + +++ ++ + S D+S GG + V E+ +G V G +L ++
Sbjct: 585 KGGKVPRVRYREERALHDLLRRIARKNMVSSVTDVSTGGLLAAVAEL-LGPV-GASLSLS 642
Query: 943 VAAN-VSPIEALFNEELGIVLEVSKNDLPYVLSEYNNNGVGAQHIG 987
N VS + L E V+ + VL GV AQ +G
Sbjct: 643 EVPNSVSRWDFLLLSESHGRAIVTTDRPDDVLGAAEEAGVPAQVVG 688
>UniRef50_UPI00015BB1F1 Cluster: phosphoribosylformylglycinamidine
synthase II; n=1; Ignicoccus hospitalis KIN4/I|Rep:
phosphoribosylformylglycinamidine synthase II -
Ignicoccus hospitalis KIN4/I
Length = 713
Score = 69.7 bits (163), Expect = 5e-10
Identities = 156/668 (23%), Positives = 243/668 (36%), Gaps = 72/668 (10%)
Query: 293 PTNVRGPSQVIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVA 352
P V+G + + F E+HN P+AV P++GA TG GG IRD+ + G +A
Sbjct: 52 PWVVKGGDAAVVDFGSVYVAFRIESHNHPSAVDPYNGAATGVGGIIRDI--LSSGAKPIA 109
Query: 353 GTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFV 412
G+L + W KG G SDYGN+ G P + G
Sbjct: 110 LLDDLIFGDL--DENLVKWHVKG----------------VVKGISDYGNRVGVPTVGG-- 149
Query: 413 QSYGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXX 472
+++ + D TR P++ +G P + P G L+V
Sbjct: 150 ETW--FDPDFTR----NPMVSVACVGVCPKDKLINGTPRPGDLIVIAGNYTGKDGLLGSS 203
Query: 473 XXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLE-SDVNPVESIHDQGAGGNG 531
++A A+Q D M L + LE D + + D G GG
Sbjct: 204 FASKNLEEGVEEEYA----AIQVPDPLMEKLL---IDSILEMRDERLLVFVKDLGGGGLA 256
Query: 532 NVLKELVEPEGAVVFTK--EFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRR 589
L E+ G V + L +P + E+ +E QE L+ + +++ +
Sbjct: 257 TALSEVAASFGLGVEARLDALHLREP-MEAWEIVVSESQERMMLVIRPEDLERAKKVLEK 315
Query: 590 ERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLES-KSKLPYDLHLEAVLGNMPRK 648
P S +G+ T G + L + EK D + E + PY+ R
Sbjct: 316 YDVPYSVIGKFTDTGRVVLYYNG--EKVADLPAKFLAEGPELDRPYE-----------RP 362
Query: 649 TFDLQTEKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVG 708
+ L+ E LP ++ + A+ +VL NVASKR++ + D V + V
Sbjct: 363 KWHLELELLPPLP-----EVDLGDAIRKVLSSPNVASKRWIYEQYDH----EVQIRTVVK 413
Query: 709 PLHTPLADCAIIALSYYDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISEL 768
P D A++ L G A + + LDP GA EA N+V +G L
Sbjct: 414 PGE---GDAAVLRLLEDPPKGIAVATDSNPRYTFLDPLWGAADVFLEAYRNVVASGARPL 470
Query: 769 EDVKCSGNWMWAGKTGVEXXXXXXXXXXXXXXMRALGVAVDGGKDSLSMCAHVAGEKVKS 828
V + + R + V + GGK S V G+++K
Sbjct: 471 AAVDQVD--AGSPERPDRFWFFVRMIDGLAWVEREVDVPIVGGKVSFYNEDDVTGKQIKP 528
Query: 829 PGTLVVSTYAPCPDITVKIEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXX 888
T++++ ++ + A EE LV V LGGS +L
Sbjct: 529 --TVMITMIGKVENV-YNAKRARAEEGDLLV--LVGETFPELGGSEFLWSVHKLVRGKPP 583
Query: 889 XXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVS 948
+ + K +K + HD+S GG V E+ G L L
Sbjct: 584 VPRPSTEARVAERILKAIKVSGVTGVHDVSVGGLAAAVAELAKGFGATLELDKVKGPWKR 643
Query: 949 PIEALFNE 956
P EALF+E
Sbjct: 644 PEEALFSE 651
>UniRef50_Q58660 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=2; Methanococcales|Rep:
Phosphoribosylformylglycinamidine synthase II -
Methanococcus jannaschii
Length = 733
Score = 69.3 bits (162), Expect = 7e-10
Identities = 144/712 (20%), Positives = 271/712 (38%), Gaps = 74/712 (10%)
Query: 302 VIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGN 361
VI+ K + + E+HN P+ + P++GA TG GG +RDV + G +A G+
Sbjct: 67 VIRLKNDICLAIAMESHNHPSYIDPYNGAATGVGGIVRDV--LSMGAKPIALLDPLRFGD 124
Query: 362 LHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNAD 421
+ + ++ W +I G DYGN+ G P + G
Sbjct: 125 I----FGKEGDKVRW-----------LIEGVVKGIGDYGNRIGVPTVGG----------- 158
Query: 422 NTREEFVKPIMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXX 481
EF ++ + + ++K+N+ G
Sbjct: 159 --ECEFDSSFDYNNLVNVVCVGLVKENEIITGKAKEPGLSLILIGSTGRDGIGGASFASK 216
Query: 482 DARDHA-LDFGAVQRGDAEMGNRLNRVVRGCLESDVNPVESIHDQGAGGNGNVLKELV-- 538
D + + + +VQ GDA L V +++ V+++ D GA G E+
Sbjct: 217 DLTEESEEERPSVQVGDAFSEKCLIDAVLEAVKT--GKVKAMKDLGAAGLSGASSEMCYG 274
Query: 539 EPEGAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVG 598
G ++ + L +P +T E+ +E QE L + + EI ++ P S +G
Sbjct: 275 GGVGCELYLENVVLREP-LTPYEIMVSESQERMLLAVEPGSEEEIIEIFKKYELPASVIG 333
Query: 599 EVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKRT 658
+ ++ E K+ K E LP DL EA L + K DL+ ++
Sbjct: 334 K-------TIPEKRIIAKY-------KGEVVVDLPLDLLCEAPLYDREGKE-DLKEKEDD 378
Query: 659 KLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCA 718
K + P+D+ + L ++L N+ SK ++ + D V + + P D A
Sbjct: 379 KEKIKMPEDL--NAVLLKLLESPNICSKEWIYQQYDHEVQ--------IRTVVKPGKDAA 428
Query: 719 IIALSYYDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWM 778
++ ++ +G A + + L+P GA ++ EA+ NL G E + N
Sbjct: 429 VLRINEVYPMGIALTTDCNSRYCKLNPYVGAVNAVAEAVRNLATVG---AEPIAMLDNLN 485
Query: 779 WAGKTGVEXX-XXXXXXXXXXXXMRALGVAVDGGKDSLSMCAHVAGEK---VKSPGTLVV 834
+ E + V GG SL + G++ +P V+
Sbjct: 486 FGNPERPERFWQLAECIKGLADAAEFFEIPVVGGNVSLYNETVIEGKEHPINPTPAIFVL 545
Query: 835 STYAPCPDITVKIEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXX 894
+ ++ +KE + ++ + K +GGS + +
Sbjct: 546 GKVEDVEKVPGVLDNKIKEGDILII---TNETKDEMGGSEYYKVIHNTEEGRVPRVDLEK 602
Query: 895 XKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNV--AANVSPIEA 952
K +++ ++++KE + D S GG + +M + GL + + N+
Sbjct: 603 EKKIYEEVREVVKEGLVSEAVDCSRGGLAVALAKMAVLNNIGLEVDLTEYNKNNLRDDIL 662
Query: 953 LFNEELG-IVLEVSKNDLPYVLSEYNNNGVGAQHIGYTGKYGMDSQVVINLN 1003
LF+E G I+L V + VLS+ ++ + + G K ++ + V+NL+
Sbjct: 663 LFSETSGRIILAVRDENKDKVLSKLSSAYIIGKVGGSRLKIKINEKDVVNLD 714
>UniRef50_Q7VC88 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=29; Bacteria|Rep: Phosphoribosylformylglycinamidine
synthase 1 - Prochlorococcus marinus
Length = 218
Score = 68.9 bits (161), Expect = 9e-10
Identities = 61/199 (30%), Positives = 91/199 (45%), Gaps = 34/199 (17%)
Query: 1102 LQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGV 1161
L ++ L+ + VV PGGFSY D L A F+ LSS K LG+
Sbjct: 32 LWHESTDLNGLEAVVLPGGFSYGDYLRCG----AIARFAPVLSSLLEFVN--KGGKVLGI 85
Query: 1162 CNGCQLMAMLGWVDPDSNSKGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGM 1221
CNG Q++ LG + P + L N F C + I + WF+
Sbjct: 86 CNGFQILTELGLL-PGA-----------LTRNQELHFICDTVPLLISSQRTQ---WFKNY 130
Query: 1222 GGSV-LGVWVAHGEGRFTVADGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGL 1280
S + + +AHGEGR+ ++ S+L KL +A++Y + NPNGS + +
Sbjct: 131 NQSKNIFLPIAHGEGRYQCSE-SILKKLQDEDSIALKYKN-----------NPNGSINDI 178
Query: 1281 AGVRSRDGRHIAMMPHPER 1299
A + ++ G + MMPHPER
Sbjct: 179 AAITNKSGNVLGMMPHPER 197
>UniRef50_Q9KF57 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=74; Firmicutes|Rep:
Phosphoribosylformylglycinamidine synthase II - Bacillus
halodurans
Length = 743
Score = 68.9 bits (161), Expect = 9e-10
Identities = 140/654 (21%), Positives = 242/654 (37%), Gaps = 72/654 (11%)
Query: 296 VRGPSQ---VIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVA 352
++GP + +I E ++F E+HN P+A+ P+ GA TG GG +RDV +G ++
Sbjct: 75 LQGPGEGAGIIDIGDEQAVVFKIESHNHPSAIEPYQGAATGVGGILRDVFSMGARPISLL 134
Query: 353 GTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFV 412
+ + G L P +E E G + YGN G P + G V
Sbjct: 135 NSLRF--GELTSPKVRYLFE------------------EVVAGIAGYGNCVGVPTVGGEV 174
Query: 413 QSYGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXX 472
Q D E P++ + +G + H I+K + KG+
Sbjct: 175 Q------FDPCYEG--NPLVNAMCVGLIDHKDIQKGQA-KGVGNTVMYVGASTGRDGIHG 225
Query: 473 XXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLESDVNPVESIHDQGAGGNGN 532
+A + AVQ GD M L ++SD + I D GA G +
Sbjct: 226 ATFASEELSEASEEKRP--AVQVGDPFMEKLLLEACLELIKSDA--LVGIQDMGAAGLTS 281
Query: 533 VLKELVEPEGAVVFTK--EFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRE 590
E+ G+ + + +T E+ +E QE ++ K +++I
Sbjct: 282 SSAEMASKAGSGIEMNLDHVPQREKGMTPYEMMLSESQERMLIVVKKGREQEIKDIVAHW 341
Query: 591 RCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYD-LHLEAVLGNMPRKT 649
VG+VT D + L+ K E + +P D L +A + + P K
Sbjct: 342 GLHAVEVGQVTDDKKLRLLH--------------KGEVVADVPVDALAEDAPVYHKPSKV 387
Query: 650 FDLQTEKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGP 709
+++ P VK L +L+ +ASK ++ + D V
Sbjct: 388 PAYYEAFQSEKTQWIPTIANVKDTLLSLLQQPTIASKEWVYEQYDYMVQ--------TNT 439
Query: 710 LHTPLADCAIIAL-SYYDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISEL 768
+ +P +D A++ + + T ++ + LDP G ++++ EA N+V +G L
Sbjct: 440 VVSPGSDAAVVRIRGTKKALAMTTDCNSRYL--FLDPEVGGKIAIAEAARNIVCSGGVPL 497
Query: 769 EDVKCSGNWMWAGKTGVEXXXXXXXXXXXXXXMRALGVAVDGGKDSLSMCAHVAGEKVKS 828
C N+ K + R LG V GG ++S+ G V
Sbjct: 498 GVTDCL-NYGNPEKPEI-FWQLEKSTDGMSEACRELGTPVIGG--NVSLYNETNGVAVYP 553
Query: 829 PGTLVVSTYAPCPDITVKIEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXX 888
T V+ D+ A K+ L++ + K GGS L +
Sbjct: 554 --TPVIGMVGLIEDVGHITTQAFKKAGD-LIYV-IGEAKAEFGGSELQKLVNGEISGKAP 609
Query: 889 XXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVN 942
K + + ++ + S HDI+EGG + E +G G ++ ++
Sbjct: 610 AIDLAVEKKRQEQLLEAIRAGAVASAHDIAEGGLAVALAESMMGEAVGADVVID 663
>UniRef50_O41978 Cluster: Tegument protein/FGARAT; n=2; Murid
herpesvirus 4|Rep: Tegument protein/FGARAT - Murid
herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68)
Length = 1291
Score = 67.3 bits (157), Expect = 3e-09
Identities = 113/528 (21%), Positives = 194/528 (36%), Gaps = 42/528 (7%)
Query: 831 TLVVSTYAPCP-DITVKIEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXX 889
T+V + A P + K P K S ++ + P K+ L S A N
Sbjct: 781 TIVFTAQATGPLYLAPKPTPDFKSPGSHIIWVSLHP-KFTLSASIAATILGLACTNLLTF 839
Query: 890 XXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSP 949
K+L K L ++S HDIS+GG IT +LEM + G RG + + A P
Sbjct: 840 DHRLVWKTL-KTINHFLTRGAILSIHDISDGGLITCLLEMAMSGRRGAEIEI-PAQVPCP 897
Query: 950 IEALFNEELGIVLEVSKNDLPYVLSEYNNNGVGAQHIGYTGKYGMDSQVVINLNGVNVLD 1009
+ + +E G + EV + E + G+ IG+ + + N +
Sbjct: 898 YQFMLSETPGFICEVDPLRAQDITCELTSQGLCFAMIGFVSGNVPPATIRCMHNRNVIYQ 957
Query: 1010 TVLIDVFRMWEETSYRLECLQANTDCVLQEWKVLEKRKGATYNVTFDPTAAVIKTKSI-- 1067
L W R ++ ++ + L YN+ P ++ + S+
Sbjct: 958 ESLAHATMYWRSGFLREHMMKVGNLTPQEQQESLSLGYNRPYNLP-RPQSSKLCALSMAP 1016
Query: 1068 -----KVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFS 1122
KV ++ G + + FD+ + +++L K G V G
Sbjct: 1017 GSSPPKVLLIVFPGQPTHHGTLTAFASMGFDIRPMDVTELY--KTDPLTVSGCVIAG--Q 1072
Query: 1123 YADTLGSAKGW--AAGILFSESLSSQFAHFKDRKDTFSLGVCN-GCQLMAMLGWVD--PD 1177
L GW A+ +L + F +K TF LG Q++ L + D
Sbjct: 1073 RGTLLSETGGWLTASALLQNLQFLDWMNTFYQQKHTFILGFGEFATQVLLALNLTEWRCD 1132
Query: 1178 SNSKGSNKAQIF----LDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHG 1233
+ ++ L N + W V + + + ++FR + GS W
Sbjct: 1133 RPFIATELEELINRPRLTANKVPLLQSLWLNVSLPPSNS---IFFRPLHGSACPAWACGT 1189
Query: 1234 EGRFTVADGSLLDKLYKNGQVAVQYVDDDG-KPTEVYPMNPNGSPDGLAGVRSRDGRHIA 1292
++ S D L G +A ++ DG P YP NP+G + +A + S DGR
Sbjct: 1190 HLGIDISSSSSGDTL-SPGLIAARFATADGTAPATYYPRNPSGGTN-VAALCSYDGRACT 1247
Query: 1293 MMPHPERCVL--RWQCPAPCPTVTNPSVRNSQASPWLRLFQNAYSWAI 1338
M+ +P + +WQ + + +Q SPW + + WA+
Sbjct: 1248 MVFNPTDSLYLHQWQ---------HLDDQEAQESPWRQCLHHLLLWAL 1286
Score = 43.2 bits (97), Expect = 0.050
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 664 FP-KDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIAL 722
FP + I S ++ +L +V SK + +DRC G V QQQ GPL P++D + I
Sbjct: 580 FPWQTINFNSFMEFLLSHPDVESKEGIVRHLDRCGQGQVVQQQGCGPLDLPVSDYSTIYT 639
Query: 723 SYYDLVGSATSIGTQNIKGLL 743
Y + T+ + L+
Sbjct: 640 GVYQSASKTIQVNTEIAQRLI 660
>UniRef50_A7D7A8 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=1; Halorubrum lacusprofundi ATCC 49239|Rep:
Phosphoribosylformylglycinamidine synthase II -
Halorubrum lacusprofundi ATCC 49239
Length = 759
Score = 66.9 bits (156), Expect = 4e-09
Identities = 116/474 (24%), Positives = 181/474 (38%), Gaps = 53/474 (11%)
Query: 311 IIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLP 370
+ F E+HN P+ V P GA TG GG +RD +G + +A + +L+ G+D
Sbjct: 90 VTFGVESHNHPSFVDPVDGAATGVGGIVRDTMSMG--AYPIA-----LLDSLYFGGFDR- 141
Query: 371 WEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKP 430
E + + ++E G S YGN G P + G V + + P
Sbjct: 142 -ERSRYLFEG--------VVE---GISHYGNCIGVPTVGGSVAFHDGYEGN--------P 181
Query: 431 IMFSGGIGYMPHSMI---KKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHA 487
++ +G + +P ++LV DA
Sbjct: 182 LVNVACVGLTNEDRLVTATAQEPGNTLMLV---GNGTGRDGLGGASFASEDLAEDAETE- 237
Query: 488 LDFGAVQRGDAEMGNRLNRVVRGCLESDVNPVESIHDQGAGGNGNVLKELVEPEG--AVV 545
D AVQ GD RL ++ D+ V S D GA G G ELV G A +
Sbjct: 238 -DRPAVQVGDPYAEKRLIECNEALVDEDL--VLSARDLGAAGLGGASSELVAKGGLGARL 294
Query: 546 FTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGEVTGDGY 605
+P + +E+ AE QE + + +E + R S +GEVT Y
Sbjct: 295 DLDSVHQREPNMNAMEILLAESQERMCYEVAPEDVARVEALAERFDLGCSVIGEVTDGNY 354
Query: 606 MSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKRTKLPLSFP 665
+ E + K D ++ +++S++ D+ E + P DL +E T+ P
Sbjct: 355 VC--EFAGAGKGEDDAD--DSDAESEVVVDVDAEYLADGAPMN--DLASESPTQPDRDLP 408
Query: 666 K-DITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQ-----CVGPLHTPLADCAI 719
+ ++ A++ V+ + ASKR++ + D V A + + T D A
Sbjct: 409 DPEPSLDEAVESVVSAPSTASKRWVYRQYDHEVGVRTAMKPGDDAAIMAIRETASTDAAD 468
Query: 720 IALSYYDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKC 773
+A + VG A S G DP GAR E TNL G L V C
Sbjct: 469 LAPADQG-VGLALSSGANPNWTETDPYEGARAVALENATNLAAKGAVPLAAVDC 521
>UniRef50_Q2GCW2 Cluster: Putative phosphoribosylformylglycinamidine
synthase II; n=1; Neorickettsia sennetsu str.
Miyayama|Rep: Putative phosphoribosylformylglycinamidine
synthase II - Neorickettsia sennetsu (strain Miyayama)
Length = 946
Score = 66.5 bits (155), Expect = 5e-09
Identities = 118/513 (23%), Positives = 189/513 (36%), Gaps = 56/513 (10%)
Query: 311 IIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLP 370
I ETHN P+A+ PF GA TG G RD+ G G +A + V + DL
Sbjct: 308 ICVKVETHNSPSALEPFGGAMTGILGVNRDILGFGLAAKPIANYYAFCVEDPDTENQDLY 367
Query: 371 WEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKP 430
+ + + T L+ II N GN G P G + A KP
Sbjct: 368 HDSHKTKPKLDSRTILKGIIRGVNAG---GNCSGIPTPQGALYFSSAFRA--------KP 416
Query: 431 IMFSGGIGYMPHSMIKKNK----PDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDH 486
++F G G +P + +K P G L+V D
Sbjct: 417 LVFVGCAGIIPAKIAEKESWVKAPRDGDLIV-----IAGGRTGRDGIHGATFSSTGITDS 471
Query: 487 ALDFGAVQRGDAEMGNRL-NRVVRGCLESDVNPVESIHDQGAGGNGNVLKELVEPEGAVV 545
+ VQ GD +L + ++R ++D+ +I D GAGG + + E+ + G VV
Sbjct: 472 NVKGTEVQLGDPFTQKKLSDAIIREVRDADL--CNAITDNGAGGLSSSVGEMGK-NGFVV 528
Query: 546 FTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGEVTGDGY 605
++ L + E+W +E QE + I + + +GE
Sbjct: 529 HLEKVLLKTIGLAPWEIWISESQERMTFAIPREKLEAFGRIMTKHGVEFAVIGE------ 582
Query: 606 MSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKRTKLPLSFP 665
+RS R + + K +DL L + P T LQT+K ++
Sbjct: 583 ------------FNRSGRGLITFEGKTVFDLSLCFLHDGNP--TIHLQTKKPREMR---G 625
Query: 666 KDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALSYY 725
+ S+L+ +R NV S++++ + D V G + G + +D I
Sbjct: 626 QPHVSFSSLEEAIRDKNVCSRKFIAEQYDHEVQGTSILKPLQGK-NEIFSDVTAIK---- 680
Query: 726 DLVGSATSIGTQNIKGLL--DPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKT 783
L S IG ++ DP S+ +A+ NLV G++ + + N+ W+
Sbjct: 681 PLYNSRKCIGQSQDLAIITRDPYLDTCSSIEKAVRNLVTIGVNP-QKIALLDNFCWSDSN 739
Query: 784 GVEXX-XXXXXXXXXXXXMRALGVAVDGGKDSL 815
E ALG GKDS+
Sbjct: 740 DPEKLWLLKEAGRACHDTSIALGTPFISGKDSM 772
>UniRef50_Q3AYR1 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=11; Cyanobacteria|Rep:
Phosphoribosylformylglycinamidine synthase 1 -
Synechococcus sp. (strain CC9902)
Length = 217
Score = 66.1 bits (154), Expect = 6e-09
Identities = 60/199 (30%), Positives = 91/199 (45%), Gaps = 34/199 (17%)
Query: 1102 LQNKKITLDAFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGV 1161
L +++ L VV PGGFSY D L A F+ L S F + LG+
Sbjct: 32 LWHEETDLSGLDAVVLPGGFSYGDYLRCG----AIARFAPVLQS-LMDFASKGGRV-LGI 85
Query: 1162 CNGCQLMAMLGWVDPDSNSKGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGM 1221
CNG Q++ LG + P + L N + F C +H + + D W +
Sbjct: 86 CNGFQVLTELGLL-PGA-----------LTRNQNLHFICE--DAPLHVSSTRTD-WLKAY 130
Query: 1222 GGSV-LGVWVAHGEGRFTVADGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGL 1280
G + L + +AHGEGR+ ++ +L +L +A++Y NPNGS D +
Sbjct: 131 GNAASLVLPIAHGEGRYQCSNDTL-KQLQDQDCIALRYGS-----------NPNGSVDDI 178
Query: 1281 AGVRSRDGRHIAMMPHPER 1299
AG+ + G + +MPHPER
Sbjct: 179 AGITNPSGNVLGLMPHPER 197
>UniRef50_Q9PHZ7 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=15; Campylobacterales|Rep:
Phosphoribosylformylglycinamidine synthase 1 -
Campylobacter jejuni
Length = 223
Score = 65.3 bits (152), Expect = 1e-08
Identities = 66/233 (28%), Positives = 111/233 (47%), Gaps = 38/233 (16%)
Query: 1067 IKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADT 1126
+KVA++R G N + + + F+ V + +++ DA VV PGGFSY D
Sbjct: 1 MKVAIIRFPGTNCEFDTTYA-----FEKLGVKTQIVWHEEKEFDA-DLVVLPGGFSYGDY 54
Query: 1127 LGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKA 1186
L A A + ++ F H K K + LG+CNG Q++ G + KG+ K
Sbjct: 55 LRCA----AIAKLAPAMQGVFNHAK--KGGYILGICNGFQILLESGLL------KGAMK- 101
Query: 1187 QIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLD 1246
HN++ F + ++++ N+N F+ ++ + +AHGEG + AD + L
Sbjct: 102 -----HNNNLSFISKNQSLRVVSNDNAFLKNFKK--DEIINLPIAHGEGNY-YADETTLK 153
Query: 1247 KLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPER 1299
+L + ++Y +P NPNGS +AG+ + + +MPHPER
Sbjct: 154 ELQDKDLIILKY-----EP------NPNGSVFDIAGICDENKKIFGLMPHPER 195
>UniRef50_Q72IH7 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=4; Bacteria|Rep: Phosphoribosylformylglycinamidine
synthase II - Thermus thermophilus (strain HB27 / ATCC
BAA-163 / DSM 7039)
Length = 725
Score = 65.3 bits (152), Expect = 1e-08
Identities = 148/684 (21%), Positives = 245/684 (35%), Gaps = 76/684 (11%)
Query: 311 IIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLP 370
+ F E+HN P+AV PF GA TG GG +RD+ + G +A G P
Sbjct: 80 VAFKIESHNHPSAVEPFQGAATGVGGILRDIMSM--GARPIALLDSLRFG---------P 128
Query: 371 WEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKP 430
EE Y ++ +G + YGN G P + G + + + RE P
Sbjct: 129 PEEARSRY---------LLKGVVSGIAFYGNAIGVPTVGGDLYFH-----EGYRE---NP 171
Query: 431 IMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDF 490
++ + +G + +K+++ G + A D
Sbjct: 172 LVNAMCLGLLREEHLKRSRASLGRPIYYAGAKTGRDGIGGAAFASRELKEEKAEDRP--- 228
Query: 491 GAVQRGDAEMGNRLNRVVRGCLESDVNPVESIHDQGAGGNGNVLKELVEPEGAVV--FTK 548
AVQ GD +G L +E D+ VE + D GA G + L EL G V
Sbjct: 229 -AVQVGDPFLGKLLMEATLEAIELDL--VEGVQDMGAAGLTSSLSELAHKSGLGVELHLD 285
Query: 549 EFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGEVTGDGYMSL 608
+ +T EL +E QE L+ + LEE+ R V + +
Sbjct: 286 LVPTREEGMTPEELLLSESQERMVLVPKEGKEKALEEVFGRWGLDCVPVARTIPERVFRV 345
Query: 609 IEDSYTEKFLDRSERLKLESKSKLPYDLHLEA-VLGNMPRKTFDLQTEKRTKLPLSFPKD 667
+ + E +++P + EA + R+ +++ + T +P P +
Sbjct: 346 L--------------FRGEVVAEVPTEALAEAPTYVRVGREDPEVRRLRETPIP---PLE 388
Query: 668 ITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALSYYDL 727
+ L R+L N+AS+ + + D V A L D A++ + L
Sbjct: 389 ADPQEVLRRLLASPNLASREAVYERYDHQVGTRTA-------LLPGKGDAAVLWIKGTRL 441
Query: 728 VGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEX 787
G A + L P GA +L EA N+ G L G + + +T
Sbjct: 442 -GVAAKVDQNPRYSRLHPRLGAMHALAEACRNVSVVGAKPL--AYTDGLNLGSPETPEGY 498
Query: 788 XXXXXXXXXXXXXMRALGVAVDGGKDSLSMCAHVAGEKVKSPGTLVVSTYAPCPDITVKI 847
ALGV V G ++S+ G+++ P T +V ++ +
Sbjct: 499 HELAETIAGLKEASEALGVPVVSG--NVSLYNESGGKRI--PPTAMVGVVGVL-EVDKRA 553
Query: 848 EPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLK 907
E + L+ G+ LG S + K++ + + L++
Sbjct: 554 EMGFRRPGEVLLLIGEERGE--LGASEVLYLLTGKEFGHPPRLDLGREKAVQEAIRDLIQ 611
Query: 908 EKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGIVL-EVSK 966
+ HD++EGG + + EM G + V +EALF E VL V K
Sbjct: 612 RGLTRTAHDVAEGGLLLALAEMTFPYGVGATVEVREEG----LEALFGEAPSRVLFTVEK 667
Query: 967 NDLPYVLSEYNNNGVGAQHIGYTG 990
L G+ + +G TG
Sbjct: 668 TRLQEATLLLEERGLPYRVLGETG 691
>UniRef50_O28339 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=3; Archaea|Rep: Phosphoribosylformylglycinamidine
synthase II - Archaeoglobus fulgidus
Length = 765
Score = 62.9 bits (146), Expect = 6e-08
Identities = 78/303 (25%), Positives = 120/303 (39%), Gaps = 29/303 (9%)
Query: 302 VIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGN 361
V++ E + E+HN P+A+ P+ GA TG GG +RDV + G +A GN
Sbjct: 102 VVEFDDEYAYVTAFESHNHPSAIEPYGGAATGIGGILRDV--LCMGAQPIALIDPLFFGN 159
Query: 362 LHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNAD 421
L D P+E + P PL ++ G DYGN+ G P ++G V D
Sbjct: 160 L-----DTPYE----KLPRGTKHPLYLLKGVVAGIRDYGNRVGIPTVAGMV------FFD 204
Query: 422 NTREEFVKPIMFSGGIGYM-PHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXX 480
N+ ++ G +G + +I G L V
Sbjct: 205 NS--YLTNCLVNVGCVGIVRKDRIIHSRAGGAGDLFV---LAGGKTGRDGIHGVTFASAE 259
Query: 481 XDARDHALDFGAVQRGDAEMGNRLNRVVRGCLE-SDVNPVESIHDQGAGGNGNVLKE--L 537
D + GAVQ G+ M L + CLE + + + D G GG V+ E L
Sbjct: 260 LDEKSEEEARGAVQLGNPIMKEPL---IHACLEVVEKGLLTGMKDLGGGGLSCVIGEMAL 316
Query: 538 VEPEGAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFV 597
GA V+ + L + + E+W +E QE L + + I ++ P + V
Sbjct: 317 AAGFGAEVYLDKVPLKEEGMAPWEIWISESQERMMLTVRPEHIDEVLYIFQKWDVPATVV 376
Query: 598 GEV 600
G+V
Sbjct: 377 GKV 379
Score = 37.9 bits (84), Expect = 1.9
Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 5/110 (4%)
Query: 178 FVVPLQEQGISAMRKVNDKLGLAFDTWDMEFYMDLFVNKLKRDPTSVELFDLAQSNSEHS 237
+ V + + + K+++++GLA +M+ D F K R+P +EL LAQ+ SEH
Sbjct: 12 YEVEILDASEEELAKISEEMGLALSVDEMKRIQDYFRQK-GRNPYDIELQSLAQAWSEHC 70
Query: 238 RHWFFKGKLVLDGKEINESLIDMVASTQKTSNNNNVIKFGDNSSAIKGFQ 287
+ K L + S D V S + V++F D + + F+
Sbjct: 71 --CYKSSKYYLRQYLLEASKADYVISA--IEEDAGVVEFDDEYAYVTAFE 116
>UniRef50_Q5Z2C3 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=36; root|Rep: Phosphoribosylformylglycinamidine
synthase II - Nocardia farcinica
Length = 764
Score = 61.7 bits (143), Expect = 1e-07
Identities = 104/462 (22%), Positives = 168/462 (36%), Gaps = 36/462 (7%)
Query: 507 VVRGCLES-DVNPVESIHDQGAGGNGNVLKELVEPE--GAVVFTKEFQLGDPTITTLELW 563
++ CLE V I D G G EL G + + L +T E+
Sbjct: 268 LIECCLELYAAKLVVGIQDLGGAGLSCATSELAAAGDGGMRIELDKVPLRAADMTPAEIL 327
Query: 564 GAEYQENDALLCSKANRHILEEICRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSER 623
+E QE + + N +CR+ + +GEVT DG L+ + E +D R
Sbjct: 328 SSESQERMCAVVTPENVEAFMAVCRKWDVLATVIGEVT-DGDR-LVVTWHGETVVDVPPR 385
Query: 624 LKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKRTKLPLSFPKDITVKSALDRVLRLVN- 682
E + P + D Q P + P+ T + +LR+++
Sbjct: 386 TVAH-----------EGPVYERPVQRPDYQDALIADTPDTLPRPATADELRETLLRMISS 434
Query: 683 --VASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALSYYDLVGSATSIGTQNIK 740
+ S++++T + DR V G + AD +I + G A +
Sbjct: 435 PQLCSRKWITEQYDRYVRGNTVLAED--------ADAGVIRIDEQTGRGIALATDASGRY 486
Query: 741 GLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEXXXXXXXXXXXXXX 800
LDP AGA+L+L EA N+ G + C N+ GV
Sbjct: 487 TKLDPYAGAQLALAEAFRNVASTGATPKAVTNCL-NFGSPEDPGVMWQFQQAVRGLADGC 545
Query: 801 MRALGVAVDGGKDSLSMCAHVAGEKVKSPGTLVVSTYAPCPDITVKIEPALKEENSALVH 860
+ ALG+ V GG S + G+ P T VV D+ +I + E +
Sbjct: 546 V-ALGIPVTGGNVSF---YNQTGQDAILP-TPVVGVLGVIDDVHRRIPTGIGLEPGETL- 599
Query: 861 APVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEG 920
+ + GGS AQ + L ++ ++ + + HD+SEG
Sbjct: 600 ILLGDTRDEFGGSIWAQVVHDHLGGVPPKVDFAREQLLAEVLTAGSRDGMISAAHDLSEG 659
Query: 921 GFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGIVL 962
G V+E + G G + + + P LF+E G VL
Sbjct: 660 GLAQAVVEAALAGETG--CRILLPEDADPFVTLFSESAGRVL 699
Score = 43.6 bits (98), Expect = 0.037
Identities = 16/35 (45%), Positives = 23/35 (65%)
Query: 311 IIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVG 345
+ F E+HN P+ V P+ GA TG GG +RD+ +G
Sbjct: 101 VTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMG 135
>UniRef50_Q2J4N0 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=31; Bacteria|Rep: Phosphoribosylformylglycinamidine
synthase 1 - Frankia sp. (strain CcI3)
Length = 233
Score = 60.5 bits (140), Expect = 3e-07
Identities = 59/194 (30%), Positives = 85/194 (43%), Gaps = 33/194 (17%)
Query: 1109 LDAFQGVVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLM 1168
L V+ PGGFSY D L + A FS +++ R LG+CNG Q++
Sbjct: 45 LAGVDAVILPGGFSYGDYLRAG----AIARFSPMVAALVP--AARAGLPILGICNGFQVL 98
Query: 1169 AMLGWVDPDSNSKGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRG-MGGSVLG 1227
G + P + L N F CR +++ E W RG G +
Sbjct: 99 CEAGLL-PGA-----------LTRNVGLHFVCRDQRLRV---EAPGTAWTRGYQDGEEIV 143
Query: 1228 VWVAHGEGRFTVADGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRD 1287
+ V HG+GR+ VA +L +L G+V V+YV NPNGS +AG+ +
Sbjct: 144 IPVKHGDGRY-VAAPDVLAELEAAGRVVVRYVGG----------NPNGSAADIAGICNES 192
Query: 1288 GRHIAMMPHPERCV 1301
+ +MPHPE V
Sbjct: 193 RTIVGLMPHPEHAV 206
>UniRef50_Q5V2D3 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=4; Halobacteriaceae|Rep:
Phosphoribosylformylglycinamidine synthase II -
Haloarcula marismortui (Halobacterium marismortui)
Length = 720
Score = 60.1 bits (139), Expect = 4e-07
Identities = 154/660 (23%), Positives = 231/660 (35%), Gaps = 77/660 (11%)
Query: 308 ESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGY 367
E I E+HN P+ V PF GA TG GG +RD +G +A +
Sbjct: 75 EMYITMGVESHNHPSYVDPFDGAATGVGGIVRDTLSMGAYPIALADCLYFG--------- 125
Query: 368 DLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEF 427
D E + + ++E G S YGN G P ++G V + D+
Sbjct: 126 DFDREHSRYLFEG--------VVE---GISHYGNCIGVPTVTGSVAFH-----DDYEG-- 167
Query: 428 VKPIMFSGGIGYM-PHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDH 486
P++ IG + P I + G LV DA
Sbjct: 168 -NPLVNVSCIGLLEPERTITAEAQEPGNKLV-LVGNATGRDGLGGASFASEDLAEDAETE 225
Query: 487 ALDFGAVQRGDAEMGNRLNRVVRGCLESDVNPVESIHDQGAGGNGNVLKELVEPE--GAV 544
D AVQ GD L L+ ++ VES D GA G G EL+ GA
Sbjct: 226 --DRPAVQVGDPYSEKLLVECNEALLDEEL--VESARDLGAAGLGGASSELIAKGGLGAR 281
Query: 545 VFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGEVTGDG 604
+ +P + +E AE QE + + + E+ R S +GE+T G
Sbjct: 282 IELDRVHEREPNMNAMEYLLAESQERMVYEVAPEDVDRVAELAERFDLGCSVIGELTEPG 341
Query: 605 YMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKRTKLPLSF 664
+Y F E ++ + D A LG+ DL ++ K
Sbjct: 342 ------TNYVCTF---------EGETVVDVD---AAFLGDGAPMN-DLPSDAPPKQERDL 382
Query: 665 PKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALSY 724
P +++ A +R++ N ASKR++ + D V V P D A++A+
Sbjct: 383 P-TVSLDEAFERIVSSPNCASKRWVYRQYDHEVQ--------VRTSVLPGDDAALLAIRE 433
Query: 725 YDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTG 784
G A S G P GAR E TN+ G + V C N K
Sbjct: 434 AG-TGLAFSAGADPNWTDAAPYEGARAVALENATNVAAKGATPHAAVDCL-NGGNPEKPD 491
Query: 785 VEXXXXXXXXXXXXXXMRALGVAVDGGKDSLSMCAHVAGEKVKSPGTLVVSTYA--PCPD 842
V L V V GG SL + G +P +V P
Sbjct: 492 V-YGGFKGIVDGLADMCSDLDVPVVGGNVSLYNDSQ-DGPIPPTPTLALVGVKEGYDAPP 549
Query: 843 ITVKIEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKIT 902
+++ E L + P RLGGS + Q G + +
Sbjct: 550 LSLSGEGRLVVVGDTALEGKTDP---RLGGS---EYTAQFGGTDRFPALPVDSTDVVETI 603
Query: 903 QKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGIVL 962
++ +++ HD+S GG T+ EM + G ++ + + +P LFNE G V+
Sbjct: 604 AEVADADHVLASHDVSHGGLAVTLAEM-VHEDAGASVEIGTTEHGTPARLLFNERPGRVV 662
>UniRef50_UPI00015BB107 Cluster: phosphoribosylformylglycinamidine
synthase I; n=1; Ignicoccus hospitalis KIN4/I|Rep:
phosphoribosylformylglycinamidine synthase I - Ignicoccus
hospitalis KIN4/I
Length = 219
Score = 58.8 bits (136), Expect = 9e-07
Identities = 66/232 (28%), Positives = 105/232 (45%), Gaps = 44/232 (18%)
Query: 1069 VAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTLG 1128
+AVL+ G NGD ++ + L + + + K+ + VV GGFSYAD L
Sbjct: 1 MAVLKFPGTNGDEDVKHVVNL-----YGMRGEVVWYKEFKQSEWDAVVLAGGFSYADRLR 55
Query: 1129 SAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQI 1188
+ G A + + ++ ++ K LG+CNG Q++ G + N A +
Sbjct: 56 A--GAIASV--TSAMDQVVEAAEEGKPV--LGICNGFQMLMERGLM--------GNGALL 101
Query: 1189 FLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKL 1248
HN + RF C+W VK+ +NK G V+ + VAH EGR+
Sbjct: 102 ---HNLNNRFVCKW--VKVMVVDNKTPWTLDYEPGEVVDMPVAHAEGRYFSES------- 149
Query: 1249 YKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRH-IAMMPHPER 1299
+ V +YV+ NPNGS +AG+ S + ++ + +MPHPER
Sbjct: 150 -EPNNVVFKYVE-----------NPNGSMWDVAGLHSPELKNVVGLMPHPER 189
>UniRef50_Q9UXW6 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=4; Thermococcaceae|Rep:
Phosphoribosylformylglycinamidine synthase II -
Pyrococcus abyssi
Length = 705
Score = 58.8 bits (136), Expect = 9e-07
Identities = 114/486 (23%), Positives = 188/486 (38%), Gaps = 72/486 (14%)
Query: 287 QHTILRPTNVRGPSQVIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGR 346
+H IL P G V++ + I+ E+HN P+AV P+ GA TG GG +RD+ +
Sbjct: 50 EHVILGPGEDAG---VVKFDESTWIVIGIESHNHPSAVEPYGGAATGIGGIVRDI--LCM 104
Query: 347 GGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEP 406
G +A G P E++ Y + G +DYGN+ G P
Sbjct: 105 GARPIALLDPIRFG---------PLEKEKNRYLFEYVV---------KGIADYGNRIGVP 146
Query: 407 VISGFVQSYGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXX 466
+ G + D + + + + GI P ++ G+ LV
Sbjct: 147 TVGGETE------FDESLDNYTLVNVVCVGI-MKPEHLVHSYVTKPGLKLV-LVGNRTGR 198
Query: 467 XXXXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLES-DVNPVESIHDQ 525
+A + D AVQ D +L ++ LE+ V+++ D
Sbjct: 199 DGIHGVTFASEELSENAEEE--DRSAVQIPD-PFTEKL--LIEATLEAVYTGKVKALKDL 253
Query: 526 GAGGNGNVLKELVEPE--GAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHIL 583
G GG E+ + GAV++ L +P +T LE+ +E QE + L
Sbjct: 254 GGGGLTCAASEMAGKKGLGAVIYADRVPLREPGMTPLEVMISESQERMLFAVEPEDVEEL 313
Query: 584 EEICRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLG 643
+I + + VGE+ IE+ +F+ K + + LP +L
Sbjct: 314 AKIFEKYELEWAVVGEI--------IEE---PRFV---VYWKGDKVADLPIELLTNVPTI 359
Query: 644 NMPRKTFDLQTEKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQ 703
P K + L+ + T DI + A D V N+ +KR++ + D V G
Sbjct: 360 EWPMKEYKLEEDVET-------PDIALSKAFDLVWSSPNIVAKRWVWEQYDHEVQGRTVV 412
Query: 704 QQCVGPLHTPLADCAIIALS-YYDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVF 762
+ P D A++ ++ Y L + TS G + L+P GA ++ E + NLV
Sbjct: 413 K--------PGFDAAVLKINGEYGL--AITSDGNPSY-CYLNPYHGAMGTVAEVVRNLVS 461
Query: 763 AGISEL 768
G L
Sbjct: 462 VGAKPL 467
>UniRef50_Q8JNB5 Cluster: BNRF1-like protein; n=1; Mustelid
herpesvirus 1|Rep: BNRF1-like protein - Mustelid
herpesvirus 1
Length = 100
Score = 56.8 bits (131), Expect = 4e-06
Identities = 27/88 (30%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
Query: 913 SGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGIVLEVSKNDLPYV 972
+GHD+S+GG +T +EM + RG+++ ++ + P+ + +E G V+EVS + L V
Sbjct: 1 AGHDVSDGGLVTCFIEMALAAQRGISMRIDEEGH--PLMQMLSETPGAVVEVSTDKLSTV 58
Query: 973 LSEYNNNGVGAQHIGYTGKYGMDSQVVI 1000
L A+ +G G YG + +++I
Sbjct: 59 LCLCEQYECPAKVLGQVGDYGPEQKIII 86
>UniRef50_Q8F0I2 Cluster: Phosphoribosylformylglycinamidine synthase
1; n=4; Leptospira|Rep: Phosphoribosylformylglycinamidine
synthase 1 - Leptospira interrogans
Length = 219
Score = 56.8 bits (131), Expect = 4e-06
Identities = 66/236 (27%), Positives = 105/236 (44%), Gaps = 37/236 (15%)
Query: 1067 IKVAVLREEGINGDREMIASLM-LANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYAD 1125
+K+AV+ G N D ++ L N +V + D +KK L V+ PGGFSY D
Sbjct: 1 MKIAVITFPGSNCDSDIYRVLKDQYNAEVDRIWHRDGLDKKYEL-----VILPGGFSYGD 55
Query: 1126 TLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNK 1185
L S G AG FS + S H F G+CNG Q++ ++ P +
Sbjct: 56 YLRS--GAMAG--FSPVMKSVKEHVDKGGKLF--GICNGFQILTEAEYL-PGA------- 101
Query: 1186 AQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLL 1245
L N + ++ C+ V + + V L + +AH +G + A +L
Sbjct: 102 ----LIRNKTLKYICK--TVILTKGSAGNPVTASMDVRKELKIPIAHADGCY-YATSDVL 154
Query: 1246 DKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCV 1301
+L ++ +Y + NPNGS D +AG+ S++ + + MMPHPER +
Sbjct: 155 KQLEDEDRILFRYSGE----------NPNGSLDSIAGITSKNFKIVGMMPHPERAM 200
>UniRef50_UPI0000383935 Cluster: COG0047:
Phosphoribosylformylglycinamidine (FGAM) synthase,
glutamine amidotransferase domain; n=1; Magnetospirillum
magnetotacticum MS-1|Rep: COG0047:
Phosphoribosylformylglycinamidine (FGAM) synthase,
glutamine amidotransferase domain - Magnetospirillum
magnetotacticum MS-1
Length = 142
Score = 56.0 bits (129), Expect = 7e-06
Identities = 37/111 (33%), Positives = 57/111 (51%), Gaps = 6/111 (5%)
Query: 1190 LDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDKLY 1249
L N + RF C +++ + + + G V+ V VAHGEG + AD + +D+L
Sbjct: 12 LMRNVNRRFICHRQFLRVERADTRFTSAYAQ--GQVIDVCVAHGEGNY-FADPATIDRLE 68
Query: 1250 KNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIA-MMPHPER 1299
G+VA +Y D +G TE N NGS + +AG+ S + MPHP +
Sbjct: 69 GEGRVAFRYCDAEGGLTE--DANRNGSLNSIAGIYSEQRNVLXHEMPHPXK 117
>UniRef50_A7HM11 Cluster: Phosphoribosylformylglycinamidine synthase
I; n=1; Fervidobacterium nodosum Rt17-B1|Rep:
Phosphoribosylformylglycinamidine synthase I -
Fervidobacterium nodosum Rt17-B1
Length = 223
Score = 55.6 bits (128), Expect = 9e-06
Identities = 61/234 (26%), Positives = 99/234 (42%), Gaps = 47/234 (20%)
Query: 1068 KVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVVFPGGFSYADTL 1127
K V+ G N DR+ + +L FD +D + +DA V+ PGGFSY D L
Sbjct: 7 KAQVVVYPGSNCDRDALWALKYVGFD------ADFVDIHGNIDA-DLVILPGGFSYGDYL 59
Query: 1128 GSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWVDPDSNSKGSNKAQ 1187
+ E ++ + F R +G+CNG Q++ +G + P +
Sbjct: 60 R-----VGAVAAREPIAYKLREFVSR-GGLVIGICNGFQILVEMGLL-PGA--------- 103
Query: 1188 IFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGEGRFTVADGSLLDK 1247
L NS F C +++ +N +F+ G V+ + +AHG GR+ DG+
Sbjct: 104 --LLQNSCGHFLCNIVELEVVDNTTPFTSYFQ--QGEVIKLPIAHGFGRYVKVDGA---- 155
Query: 1248 LYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPERCV 1301
Q +Y D NGS + +AG+ + + +MPHPER +
Sbjct: 156 -----QTVFRYTKD-----------VNGSDELIAGITNSSKNILGLMPHPERAI 193
>UniRef50_A3H6X8 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=1; Caldivirga maquilingensis IC-167|Rep:
Phosphoribosylformylglycinamidine synthase II -
Caldivirga maquilingensis IC-167
Length = 724
Score = 55.6 bits (128), Expect = 9e-06
Identities = 74/296 (25%), Positives = 119/296 (40%), Gaps = 39/296 (13%)
Query: 311 IIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLP 370
+ F E+HN P+AV P+ GA TG GG +RD+ + G +A + NLH+ D
Sbjct: 72 VTFKIESHNHPSAVDPYDGAATGVGGIVRDI--LTTGLRPIA-----LLDNLHLGSLD-- 122
Query: 371 WEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKP 430
++ N II+ G SDYGN+ G PV+ G +++ ++ +N P
Sbjct: 123 -NQRSLWLSRN-------IIK---GISDYGNRIGVPVVGG--ETWFDESFNN------NP 163
Query: 431 IMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDF 490
I+ IG + + G L++ D D
Sbjct: 164 IVLVTCIGAGDFKRVIWGEGKVGDLVLVVGNDTGRDGMLGSSFASRELSSSD------DI 217
Query: 491 GAVQRGDAEMGNRLNRVVRGCLESDVNPVESIHDQGAGGNGNVLKELVEP--EGAVVFTK 548
GAVQ G+ + L + E + V++I D G GG L EL G V
Sbjct: 218 GAVQVGNPLLEKLLIDALMELGERGL--VKAIKDVGGGGLATALSELAHQLGLGIEVDLT 275
Query: 549 EFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGEVTGDG 604
+L D + E+ +E QE ++ + +E + R+ +G++T DG
Sbjct: 276 NIRLRD-ELKPEEILVSESQERMIIVVDPSRLSYVEAVLRKYEVGFDLIGKLTNDG 330
>UniRef50_Q8PYK1 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=5; Methanosarcinaceae|Rep:
Phosphoribosylformylglycinamidine synthase II -
Methanosarcina mazei (Methanosarcina frisia)
Length = 716
Score = 55.2 bits (127), Expect = 1e-05
Identities = 107/465 (23%), Positives = 177/465 (38%), Gaps = 72/465 (15%)
Query: 316 ETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKG 375
E+HN P+ V P++GA TG GG +RD+ + G +A L P Y P +
Sbjct: 77 ESHNHPSYVDPYNGAATGVGGIVRDI--ISMGARPIA---------LMDPLYFGPLDT-- 123
Query: 376 WEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKPIMFSG 435
P N QII G + YGN G PV++G + + + N P++
Sbjct: 124 ---PKNLFLFEQII----KGIAGYGNCIGVPVVNG-ETFFDRRYSGN-------PLVNVV 168
Query: 436 GIGYMPHSMIKKNKPDK--GMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDFGAV 493
+G + ++ K L++ +A D +V
Sbjct: 169 AVGLCKEEKVMTSRSQKAGNKLILAGSSTGKDGLGGASFASRDLSESAEAEDRP----SV 224
Query: 494 QRGDAEMGNRLNRVVRGCLES-DVNPVESIHDQGAGGNGNVLKELVEPE--GAVVFTKEF 550
Q GD +L V+ LE+ D ++S D GA G G EL GA +
Sbjct: 225 QVGD-PYTEKL--VMEMTLEAIDKGYIKSCKDLGAAGLGGASSELAAKGGLGAYIIADAV 281
Query: 551 QLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGEVTGDGYMSLIE 610
+P + E+ AE QE + + + + ++ + +G +T +
Sbjct: 282 PQREPEMNAYEILLAESQERMVFEVAPEDVDAVLALVQKYDLNGAVIGHLTE-------K 334
Query: 611 DSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMP--RKTFDLQTEKRTKLPLSFPKDI 668
+YT +F + ++ D+ + + G P K + + P+D+
Sbjct: 335 PNYTVEF-----------RGEIVADIPIGFLTGGAPTCEKPSEAPIHREEGKKPETPEDL 383
Query: 669 TVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLADCAIIALSYYDLV 728
K+A +VL N+ASK ++ + D V + + P D ++ ++ D
Sbjct: 384 --KAAFMKVLSSHNIASKEWIYRQYDHEVQ--------LRTVVKPGEDSGVLRIT--DKK 431
Query: 729 GSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKC 773
G A S G Q LLDP G R ++ E NL G L V C
Sbjct: 432 GIALSCGCQPRATLLDPYTGGRTAIIENAMNLAVKGAEGLAIVNC 476
>UniRef50_A7DSW4 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
Phosphoribosylformylglycinamidine synthase II -
Candidatus Nitrosopumilus maritimus SCM1
Length = 721
Score = 54.0 bits (124), Expect = 3e-05
Identities = 97/419 (23%), Positives = 165/419 (39%), Gaps = 71/419 (16%)
Query: 291 LRPTNVRGPSQVIQKKTESDI-------IFTA--ETHNMPTAVAPFSGATTGTGGRIRDV 341
L+ ++GP + +K +S + + TA E+HN P+AV P+ GA TG GG IRD+
Sbjct: 44 LKMLPMKGPLVITEKGYDSGVLDVGDGYVVTAHIESHNHPSAVEPYGGAATGVGGVIRDI 103
Query: 342 QGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGN 401
+ G +A G G++ ++ W + + A G +DYGN
Sbjct: 104 --LSAGTRPIAIFDGLRFGDIEKD------QQARWLFKN-----------AVTGIADYGN 144
Query: 402 KFGEPVISGFVQSYGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKNKPDKGMLLVKXXX 461
G P I G V+ D E + ++ +G+ + KN KG ++V
Sbjct: 145 CLGIPTIGGEVE------FDKCYENYA--LVDVAAVGFGKKENLIKNHAKKGDIVVLMGG 196
Query: 462 XXXXXXXXXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLES-DVNPVE 520
D AVQ D + +L ++ LE+ + +
Sbjct: 197 STGRDGIGGSQFASDSLESEDR-------SAVQIPDPFI-EKL--IIEAILEARNDKLIH 246
Query: 521 SIHDQGAGGNGNVLKELVE--PEGAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKA 578
++ D G GG + E + G + + + + E+ +E QE ++ SK
Sbjct: 247 AMKDLGGGGLSCAISETADALEIGIEMDVDKVHTRESGMHPDEIMVSESQERMLIVTSKT 306
Query: 579 NRHILEEICRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHL 638
L+ IC++ R S +G V D M + + T + LP D+
Sbjct: 307 KFKKLQAICKKFRIGCSVIGTVKSDNQMHVKKGKKT--------------FANLPTDVVA 352
Query: 639 EAVLGNMPRK--TFDLQTEKRTKL-PLSFPKDITVKSALDRVLRLVNVASKRYLTNKVD 694
A L ++P K T+ EK KL P+S + ++L N+ASK ++ + D
Sbjct: 353 NATLLDLPSKEPTYLKTIEKEKKLKPIS-----DYSKTMMKLLSSPNIASKIWVYGQYD 406
>UniRef50_Q8KD17 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=20; Bacteria|Rep:
Phosphoribosylformylglycinamidine synthase II -
Chlorobium tepidum
Length = 759
Score = 53.6 bits (123), Expect = 4e-05
Identities = 148/697 (21%), Positives = 242/697 (34%), Gaps = 86/697 (12%)
Query: 311 IIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLP 370
+ F E+HN P+AV P+ GA TG GG RD+ G VA G+ P
Sbjct: 88 VAFKIESHNHPSAVEPYQGAATGVGGIHRDI--FTMGARPVASLDSLRFGSPRDPRV--- 142
Query: 371 WEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKP 430
Y ++ G DYGN FG P + G + + P
Sbjct: 143 ------RY---------LVDGVVRGIGDYGNSFGVPTVGGEIYFEDCYTGN--------P 179
Query: 431 IMFSGGIGYMP-HSMIKKNKPDKG--MLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHA 487
++ +G + H + KG +L+V D R
Sbjct: 180 LVNVMSVGLVEHHKTVSATAWGKGNPVLIVGSSTGRDGIHGATFASEDLSEASEDKRP-- 237
Query: 488 LDFGAVQRGDAEMGNRLNRVVRGCLES-DVNPVESIHDQGAGGNGNVLKEL----VEPEG 542
+VQ GD +L ++ LE+ V + D GA G + E+ +E G
Sbjct: 238 ----SVQVGD-PFAEKL--LLEATLEAIATGAVVGLQDMGAAGLTSSTSEMSARGIEKTG 290
Query: 543 AVVFTKEFQL---GDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGE 599
+ + L + +T EL +E QE ++ K H + ++ ++ +G+
Sbjct: 291 SGGIEIDLDLTPAREKGMTAYELMLSESQERMLIVAEKGREHEIIDVYKKWDVSAVVIGQ 350
Query: 600 VTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKRTK 659
VT D + + R E +++P VLG EK+
Sbjct: 351 VTDDNMLRV--------------RHHGEVVAEIP---ATSLVLGGGAPVYIREAVEKKPD 393
Query: 660 LP---LSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTPLAD 716
P L + K+ ++L N+ASK ++ + D V Q V P D
Sbjct: 394 TPAADLVADDSLDFKALSLQLLSRPNIASKAWVYQQYDSMV-----QTNTVTP--AGQTD 446
Query: 717 CAIIALSYYDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGN 776
A+I + G A + L+P AG +++ E N+ G L C N
Sbjct: 447 AAVIRIK-GTKKGLAMKTDCNSRYVYLNPKAGGAIAVAECARNIACTGAKPLAVTNCL-N 504
Query: 777 WMWAGKTGVEXXXXXXXXXXXXXXMRALGVAVDGGKDSLSMCAHVAGEKVKSPGTLVVST 836
+ K V R + GG S + G + T +
Sbjct: 505 FGNPYKPEV-YFQFKSAVEGIGDACRMFDTPITGGNVSFYNETSLGGGRTAIYPTPTIGM 563
Query: 837 YAPCPDITVKIEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXK 896
+I +E ++ A+V +P G L Y G + K
Sbjct: 564 IGLLDNIDNLVESTFRKAGDAIVLLG-APELSLDGSEYLVMQYGTPGTD-SPAVDLNHEK 621
Query: 897 SLFKITQKLLKEKKLISGHDISEGGFITTVLEMGI-GGVRGLNLHVNVAANVSPIEA--- 952
+L ++ L +K + S HD+S+GG T+ E I R L V++ + A
Sbjct: 622 NLQELLVTLASKKLINSAHDVSDGGLAVTLAEKSIMNRERMLGFEVDLECSCKEGTAIQK 681
Query: 953 -LFNEELG-IVLEVSKNDLPYVLSEYNNNGVGAQHIG 987
LF+E G +V+ V + V+ E + + + IG
Sbjct: 682 QLFSEAQGRVVISVDPGRVGAVIEEADRLNIPGRVIG 718
>UniRef50_Q4J8F8 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=4; Sulfolobaceae|Rep:
Phosphoribosylformylglycinamidine synthase II -
Sulfolobus acidocaldarius
Length = 710
Score = 52.4 bits (120), Expect = 8e-05
Identities = 72/296 (24%), Positives = 112/296 (37%), Gaps = 44/296 (14%)
Query: 311 IIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLP 370
++ E+HN P+A+ PF+GA TG GG IRD+ + +G +A VGNL+
Sbjct: 77 VVLKLESHNHPSAIDPFNGAATGIGGIIRDI--ISKGARPIALLDMIRVGNLNN------ 128
Query: 371 WEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKP 430
W + A G YGN G PV++G + D T + P
Sbjct: 129 -SRNRWLLKNIIA-----------GIGFYGNSIGVPVVAGELA------FDETYND--NP 168
Query: 431 IMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDF 490
++ G+G + I + + L + D +
Sbjct: 169 LVDVAGLGVVKKDKIVPSVVKEAGLKIVLVGLTGLDGLGGASFASRKLSGED------EI 222
Query: 491 GAVQRGDAEMGNRLNRVVRGCLESDVNPVESIHDQGAGGNGNVLKELVEPEGAVVFTKEF 550
GAVQ D G ++V + VE+I D G GG + E+ G V +
Sbjct: 223 GAVQIADPFAG----KIVLDVTLQIADKVEAIKDLGGGGLVVGITEMANGLGVEVELDKI 278
Query: 551 QLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRR---ERCPVSFVGEVTGD 603
L +T E+ +E QE + K R ++E+C P + +GE T D
Sbjct: 279 PLRVKDLTPGEILVSETQER-MVFAVKPER--VKEVCEAFEYYEYPCAVIGEFTND 331
Score = 38.7 bits (86), Expect = 1.1
Identities = 33/122 (27%), Positives = 60/122 (49%), Gaps = 9/122 (7%)
Query: 870 LGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEM 929
+GGS LA+ + GD S ++ K + + K+I DIS+GG + +L +
Sbjct: 558 MGGSLLAKIFGNYGDVPKTRLNEELLSS--ELVIKAINDGKIIFAKDISKGGLVGALLPI 615
Query: 930 GIGGVRGLNLHVNVAANVSP--IEALFNEELG--IVLEVSKNDLPYVLSEYNNNGVGAQH 985
+ G G+++ N+ + + I LF+E G IVL ++D+ ++ E + G+
Sbjct: 616 LVRGF-GVSIDTNLIPSDTDDVISKLFSENGGRFIVLSEREDDINWL--ESQSRGIYVSK 672
Query: 986 IG 987
IG
Sbjct: 673 IG 674
>UniRef50_Q5WW17 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=4; Legionella pneumophila|Rep:
Phosphoribosylformylglycinamidine synthase II -
Legionella pneumophila (strain Lens)
Length = 780
Score = 51.6 bits (118), Expect = 1e-04
Identities = 40/146 (27%), Positives = 65/146 (44%), Gaps = 9/146 (6%)
Query: 824 EKVKS--PGTLVVSTYAPCPDITVKIEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQ 881
E VK P + ++S PDI I K+ +S L+ + K GGS Q + Q
Sbjct: 586 ESVKGAIPPSPMISCLGTLPDIDFAITFDFKKSDSLLIL--IGERKDECGGSVYYQLHNQ 643
Query: 882 LGDNXXXXXXXXXXKSLFKITQKLLKEKKLISG-HDISEGGFITTVLEMGIGGVRGLNLH 940
LG N + + ++ + + L++ HD+SEGG + EM G+ +
Sbjct: 644 LGSNVPKPDLSLFNREIHAVSSAI--QLGLVNAAHDVSEGGVAVALAEMSFKNSLGVAVQ 701
Query: 941 VNVAANVSPIEALFNEELGIVLEVSK 966
+N +S + LF E G +LE+ K
Sbjct: 702 IN--GELSTDKLLFGETGGFILEIDK 725
Score = 44.8 bits (101), Expect = 0.016
Identities = 26/77 (33%), Positives = 36/77 (46%), Gaps = 4/77 (5%)
Query: 288 HTILRPTNVRGPSQVIQKKT--ESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVG 345
H IL G V Q K +I + E+HN P+ + P+ GA TG GG +RDV
Sbjct: 80 HVILGAKEDAGIVSVAQDKNGYRYGVIVSHESHNHPSQIVPYEGAATGVGGNVRDV--CC 137
Query: 346 RGGHTVAGTAGYSVGNL 362
GG +A G++
Sbjct: 138 MGGEVIAVADSLRFGDI 154
>UniRef50_A3EVN1 Cluster: Phosphoribosylformylglycinamidine synthase,
glutamine amidotransferase domain; n=2; Leptospirillum
sp. Group II UBA|Rep: Phosphoribosylformylglycinamidine
synthase, glutamine amidotransferase domain -
Leptospirillum sp. Group II UBA
Length = 255
Score = 51.2 bits (117), Expect = 2e-04
Identities = 55/193 (28%), Positives = 88/193 (45%), Gaps = 32/193 (16%)
Query: 1115 VVFPGGFSYADTLGSAKGWAAGILFSESLSSQFAHFKDRKDTFSLGVCNGCQLMAMLGWV 1174
V+ PGGFSY D L + AA +++ +FA ++ LG+CNG Q++ G +
Sbjct: 65 VILPGGFSYGDYLRTG-AMAAQTPVMKAIR-KFA----QEGHPVLGICNGFQILVETGLL 118
Query: 1175 DPDSNSKGSNKAQIFLDHNSSERFECRWSAVKIHENENKEDVWFRGMGGSVLGVWVAHGE 1234
P + L N+S F C S V + G+ + + +AH E
Sbjct: 119 -PGA-----------LLINASRSFICEDSPVVSLTSRTPFTSIIPE--GTRINLPIAHQE 164
Query: 1235 GRFTVADGSLLDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMM 1294
GR+ + + L + + +GQV +Y + NPNGS +AGV + +G + +M
Sbjct: 165 GRYYLPEDKLRN-IEASGQVVFRYAN-----------NPNGSIHDIAGVSNPEGNVVGLM 212
Query: 1295 PHPERCVLRWQCP 1307
PHPER + P
Sbjct: 213 PHPERRIRHSSSP 225
>UniRef50_A3CWL7 Cluster: Phosphoribosylformylglycinamidine (FGAM)
synthase glutamine amidotransferase domain-like protein;
n=1; Methanoculleus marisnigri JR1|Rep:
Phosphoribosylformylglycinamidine (FGAM) synthase
glutamine amidotransferase domain-like protein -
Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 /
JR1)
Length = 122
Score = 50.0 bits (114), Expect = 4e-04
Identities = 24/55 (43%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
Query: 1245 LDKLYKNGQVAVQYVDDDGKPTEVYPMNPNGSPDGLAGVRSRDGRHIAMMPHPER 1299
L +L + G+VA ++ D+ G T NPNGS + +AG+ S +AMMPHPER
Sbjct: 38 LSRLNREGRVAFRFCDEHGNVTP--ESNPNGSAEKIAGLLSEGNNVLAMMPHPER 90
>UniRef50_Q7VF52 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=18; Epsilonproteobacteria|Rep:
Phosphoribosylformylglycinamidine synthase II -
Helicobacter hepaticus
Length = 745
Score = 50.0 bits (114), Expect = 4e-04
Identities = 147/708 (20%), Positives = 252/708 (35%), Gaps = 76/708 (10%)
Query: 293 PTNVRGPSQ---VIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGH 349
P V+GP + +I +F E+HN P+ + P +GA TG GG +RD+ G
Sbjct: 72 PWVVQGPGENAGIIDIGENLCAVFKIESHNHPSFIEPHAGAATGVGGIMRDI--FTMGAR 129
Query: 350 TVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVIS 409
VA G++ G L+ ++E G YGN G P I
Sbjct: 130 PVASLNSIRFGDISDNG----------TLGKKHRYLLRGVVE---GIGSYGNCMGVPTIG 176
Query: 410 GFVQSYGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXX 469
G + N + F ++ I Y K ++ V
Sbjct: 177 GEMSFESCYNGNILVNAFCLGLVKKDEIFYG-----KAEGIGNPVIYVGSKTGRDGLGGA 231
Query: 470 XXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLE-SDVNPVESIHDQGAG 528
R AVQ GD +L ++ CLE + + I D GA
Sbjct: 232 VMSSDSFSSTSKAVR------SAVQVGD-PFAEKL--LLEACLELFKQDLIVGIQDMGAA 282
Query: 529 GNGNVLKELV--EPEGAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEI 586
G + E+ G ++ + + + + EL +E QE + K + +I
Sbjct: 283 GLTSSSFEMAGRSGSGMTLYLDKVPMREEGMNPYELMLSESQERMLICAKKGCEQQVLDI 342
Query: 587 CRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPY-DLHLEAVLGNM 645
+ + +GEVT G M L Y EK +++P L A + +M
Sbjct: 343 FAKWEVDAAIIGEVTKSGIMELF--WYGEKC------------AEIPIAQLSENAPMLDM 388
Query: 646 PRKTFDLQTEKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQ 705
P + +QT K +L S + + +L V VA+KR++ ++ D V Q
Sbjct: 389 PLRPVAVQTHKANQLKTS----QSAQEIFITLLGSVEVANKRWVYSQYDSSV-----QSN 439
Query: 706 CVGPLHTPLADCAIIALSYYDLVGSATSIGTQ-NIK-GLLDPAAGARLSLGEALTNLVFA 763
+ P + D ++I + SA S+ N++ LDP GA++++ + N +
Sbjct: 440 TITPAGS--GDASMIRIKG---TNSALSMSVDCNMRYCYLDPKNGAKIAVATSGRNSIVN 494
Query: 764 GISELEDVKCSGNWMWAGKTGVEXXXXXXXXXXXXXXMRALGVAVDGGKDSLSMCAHVAG 823
G L C + + L V G SL H
Sbjct: 495 GAKPLAISDCLN--FGSPHNPEVMWAFKEVCQGIKESCKVLNTPVVSGNVSL----HNQS 548
Query: 824 EKVKSPGTLVVSTYAPCPDITVKIEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLG 883
+ V T + + D++ + + + + LV + K GGS + +
Sbjct: 549 DGVDIYPTPSIVSVGLIDDVSKVVSSTFQTQGNMLV--LLGEIKAEFGGSLAQKILEGHI 606
Query: 884 DNXXXXXXXXXXKSLFKITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNV 943
+L+ + + E L + DI EGG T+ +M +G + NV
Sbjct: 607 YGQIPSIDLTQEFALWNLMLEASDECMLSAAKDIGEGGLAITLAKMALGNGECQPIGCNV 666
Query: 944 AANVSPIEALF-NEELGIVLEVSKNDLPYVLSEYNNNGVGAQHIGYTG 990
++ P + LF + I++EV+ L + + + + IG G
Sbjct: 667 HTHL-PSQLLFAPSQSCIIVEVAGEHLNTLKQKAKQHKIAFTEIGCVG 713
>UniRef50_A4M897 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=1; Petrotoga mobilis SJ95|Rep:
Phosphoribosylformylglycinamidine synthase II -
Petrotoga mobilis SJ95
Length = 727
Score = 49.6 bits (113), Expect = 6e-04
Identities = 105/461 (22%), Positives = 163/461 (35%), Gaps = 60/461 (13%)
Query: 311 IIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLP 370
++F E+HN P+AV P+ GA TG GG +RD+ + G +A GN+ P
Sbjct: 79 VVFKVESHNHPSAVEPYQGAATGIGGIVRDI--LAMGARPIALLDSLKFGNVFDPKVK-- 134
Query: 371 WEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFVQSYGLKNADNTREEFVKP 430
I +G SDYGN G P + G S+ + N +
Sbjct: 135 ----------------NIFEGVVSGISDYGNSIGVPTVGG-ETSFNEIYSTNP----LIN 173
Query: 431 IMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDARDHALDF 490
+M G + + PDK LLV D R
Sbjct: 174 VMCVGVANKNHLASSHADGPDK--LLVYVGSKTGRDGIHGASFASKKLSGKDDRP----- 226
Query: 491 GAVQRGDAEMGNRLNRVVRGCLESDVNPVESIHDQGAGGNGNVLKELVEP--EGAVVFTK 548
+VQ GD L L+ + V + D GA G + E+ G ++
Sbjct: 227 -SVQVGDPFTEKNLIEATLEILK--IKGVRACQDMGAAGVLSSTSEMAYKGGVGCELYLD 283
Query: 549 EFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGEVTGDGYMSL 608
I E+ +E QE L + +E IC + + +G+ + +
Sbjct: 284 NIPKRQEDIEPWEIMLSESQERMLFLVNPGTEKKVEAICNKYLIDFAVIGKTISTPHYVV 343
Query: 609 IEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKRTKLPLSFPKDI 668
E+S + D L ++ P E N T+ L K K P + KDI
Sbjct: 344 KENSEGKVLAD----LPIDILVNAP-----EYYRNNTIPSTYIL--NKAKKYPKTKIKDI 392
Query: 669 TVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPLHTP-LADCAIIALSYYDL 727
L +L N++SK+++ + D V + P AD A++ L
Sbjct: 393 --DKILKILLSNHNISSKKWIYQQYDYKVE--------TNTIFIPEQADSAVLWLKKTQ- 441
Query: 728 VGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISEL 768
A +I + + LDP G + + EA NL+ G L
Sbjct: 442 KAIAVTIDSNELYTYLDPFEGTKNVVYEAARNLISVGAKPL 482
>UniRef50_Q9X0X3 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=5; Thermotogaceae|Rep:
Phosphoribosylformylglycinamidine synthase II -
Thermotoga maritima
Length = 603
Score = 48.4 bits (110), Expect = 0.001
Identities = 22/55 (40%), Positives = 31/55 (56%)
Query: 291 LRPTNVRGPSQVIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVG 345
L T G + V+ + F E+HN P+A+ P++GA TG GG IRDV +G
Sbjct: 45 LPKTGFEGNAGVVNLDDYYSVAFKIESHNHPSAIEPYNGAATGVGGIIRDVLAMG 99
>UniRef50_Q2NEB6 Cluster: Phosphoribosylformylglycinamidine synthase
2; n=4; Methanobacteriaceae|Rep:
Phosphoribosylformylglycinamidine synthase 2 -
Methanosphaera stadtmanae (strain DSM 3091)
Length = 723
Score = 46.4 bits (105), Expect = 0.005
Identities = 99/487 (20%), Positives = 182/487 (37%), Gaps = 69/487 (14%)
Query: 293 PTNVRGPSQ---VIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGH 349
P + GP ++ E + E+HN P+AV P+ GA TG GG +RD+ + G
Sbjct: 52 PDVILGPGDDAGIVSLTDEYALAIGMESHNHPSAVEPYGGAGTGIGGIVRDI--ISMGAK 109
Query: 350 TVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVIS 409
V G++ + +Y ++ G SDYGN+ G P +
Sbjct: 110 PVVLLDALRFGHM---------SNQRSKYIFDYVV---------KGISDYGNRIGVPTVG 151
Query: 410 GFVQSYGLKNADNTREEFVKPIMFSGGIGYMPHSMIKKNKPDKG-MLLVKXXXXXXXXXX 468
G ++ DN + + ++ +G + ++ + P G + L+
Sbjct: 152 GEIEF-----DDNFQYNPMVNVVCAGLV--KKDEIVYGSAPIVGDVYLLMGGTTGRDGIH 204
Query: 469 XXXXXXXXXXXXXDARDHALDFGAVQRGDAEMGNRLNRVVRGCLESDVNPVESIHDQGAG 528
+ D AVQ D R+ LE+ + + D G G
Sbjct: 205 GVTFASEELTSNSEVEDRP----AVQVADPFTKKRVMEATYELLET--LDIHGVKDLGGG 258
Query: 529 GNGNVLKELVEP--EGAVVFTKEFQLGDPTITTLELWGAEYQENDALLCSKANRHILEEI 586
G L E+ + G+++ + L + +T E+ +E QE ++ EI
Sbjct: 259 GLTCCLSEMADKGGNGSLIDLNKIPLREENMTPYEIMLSESQERMVFAIDSSDVEKAFEI 318
Query: 587 CRRERCPVSFVGEVTGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMP 646
C++ + +G + D +I+D E P L EA +
Sbjct: 319 CKKHDLAHAIIGNII-DKREFIIKDDE-------------EEICHAPNILFTEAPIIERE 364
Query: 647 RKTFDLQTEKRTKLPLSFPKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQC 706
K + EK + + P ++ V+ AL ++L N+ SK ++ ++ D V
Sbjct: 365 AK----EPEKIIE-DVEIP-EVDVEEALYKLLSSENITSKEWVYSQYDHEVQ-------- 410
Query: 707 VGPLHTPLADCAIIALSYYDLVGSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGIS 766
+ + P D A+I + T + ++ LL+P GA ++ E++ N + G
Sbjct: 411 LRTIVKPGDDAAVIKVDDETSFTIGTDCNSTHV--LLNPYDGAASAVLESINNAISMGAR 468
Query: 767 ELEDVKC 773
+ V C
Sbjct: 469 PIALVDC 475
>UniRef50_Q7VEK9 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=34; Cyanobacteria|Rep:
Phosphoribosylformylglycinamidine synthase II -
Prochlorococcus marinus
Length = 793
Score = 46.0 bits (104), Expect = 0.007
Identities = 167/750 (22%), Positives = 269/750 (35%), Gaps = 97/750 (12%)
Query: 311 IIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLP 370
+ F E+HN P+A+ PF GA TG V G+ R T+ + +L D P
Sbjct: 92 LAFKIESHNHPSAIEPFQGAATG-------VGGILRDIFTMGARPIALLNSLRFGPLDTP 144
Query: 371 WEEKGWEYPSNFATPLQIIIEASNGASDYGNKFGEPVISG---FVQSYG---LKNADNTR 424
+ ++ +G + YGN G P + G F +SY L NA
Sbjct: 145 IN-------------VGLLEGVVSGIAHYGNCVGVPTVGGEVAFDKSYSGNPLVNAMALG 191
Query: 425 EEFVKPIMFSGGIGYMPHSMIKKNKPDKGMLLVKXXXXXXXXXXXXXXXXXXXXXXXDAR 484
K I+ SG G D ++ V D R
Sbjct: 192 IMETKEIVCSGAKGI-----------DFPVIYVGSTTGRDGMGGASFASSELTQASIDDR 240
Query: 485 DHALDFGAVQRGDAEMGNRLNRVVRGCLES-DVNPVESIHDQGAGGNGNVLKELVEPEGA 543
AVQ GD + L + GCLE+ V + D GA G E+ +G
Sbjct: 241 P------AVQVGDPFLEKGL---IEGCLEAFKTGYVVAAQDMGAAGLTCSCSEMAA-KGG 290
Query: 544 VVFTKEFQL---GDPTITTLELWGAEYQENDALLCSKANRHILEEICRRERCPVSFVGEV 600
V + L + +T E +E QE + ++ R+ VG+V
Sbjct: 291 VGIELDLDLVPAREKNMTAYEFLLSESQERMLFVVEPGKEELIMNKFRKWGLQAKVVGKV 350
Query: 601 TGDGYMSLIEDSYTEKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKRTKL 660
+ + +I + L ++ L ++ P + H +L P D T L
Sbjct: 351 LEENIVRVIHEKQIVVNLP-ADSLAEDT----PVNKH--ELLEEPPGFIKDHWKWDETSL 403
Query: 661 P------LSFPKDITVKSALDRVLRLVN---VASKRYLTNKVDRCVTGLVAQQQCVGPLH 711
P + F ++ T+ +LRL++ +ASKR++ N+ D V + P
Sbjct: 404 PKVSIKGVHFKENNTILDWNQIILRLLDDPTIASKRWIYNQYDY----QVQNNTIIAP-- 457
Query: 712 TPLADCAIIALSYYDLV------GSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGI 765
+ D A+I L + G A + N LDP GA ++ EA N+ G
Sbjct: 458 -GIGDAALIRLREIENQNQNSNRGIAAVVDCPNRWVALDPERGAIAAVAEASRNISCVGA 516
Query: 766 SELEDVKCSGNWMWAGKTGVEXXXXXXXXXXXXXXMRALGVAVDGGKDSL-SMCAHVAGE 824
L V + N+ + + + L V GG SL + A G
Sbjct: 517 KPLA-VTDNLNFS-SPEDPIGYWQLAKACKGLSKACVVLETPVTGGNVSLYNETALPNGL 574
Query: 825 KVKSPGTLVVSTYAPCPDITVKIEPALKEENSA--LVHAPVSPGKYRLGGSALAQC-YKQ 881
K T VV DI K++ L+ + P +LA Y +
Sbjct: 575 KQPIQPTPVVGMIGLIQDINSATRQGWKDQGDQIYLLGTSIDPSILNNQNISLAATSYLE 634
Query: 882 LGDNXXXXXXXXXXKSLFKITQKLLKEK---KLI-SGHDISEGGFITTVLEMGIGGVRGL 937
K+ Q L+E LI S HDIS+GG + + E I GL
Sbjct: 635 NIYGLKTGRPPLIDLEFEKLVQLFLRESIANNLIKSAHDISDGGLVIGLAESCISS--GL 692
Query: 938 NLHVNVAANVSPIEALFNEELG--IVLEVSKNDLPYVLSEYNN-NGVGAQHI--GYTGKY 992
+ N+ + ++ L E G +++ VS N++ + + NN N ++ I Y G
Sbjct: 693 GIECNLPEIDNRLDKLLFAEGGSRVLVSVSPNNIHNIKNSLNNFNIANSEQISFNYLGTV 752
Query: 993 GMDSQVVINLNGVNVLDTVLIDVFRMWEET 1022
+ IN+N ++D + ++ +E +
Sbjct: 753 TDNKYFQININQTKIIDLSVNEITNKFERS 782
>UniRef50_A0RYV3 Cluster: Phosphoribosylformylglycinamidine (FGAM)
synthase, synthetase domain; n=1; Cenarchaeum
symbiosum|Rep: Phosphoribosylformylglycinamidine (FGAM)
synthase, synthetase domain - Cenarchaeum symbiosum
Length = 713
Score = 45.2 bits (102), Expect = 0.012
Identities = 34/97 (35%), Positives = 45/97 (46%), Gaps = 19/97 (19%)
Query: 316 ETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKG 375
E+HN P+AV P+ GA TG GG +RD+ + G VA G G++ + W +G
Sbjct: 78 ESHNHPSAVEPYGGAATGVGGVVRDI--LSAGTRPVAILDGLRFGDIASDPH-ARWLLRG 134
Query: 376 WEYPSNFATPLQIIIEASNGASDYGNKFGEPVISGFV 412
A +G SDYGN G P I G V
Sbjct: 135 ----------------AISGISDYGNCIGVPTIGGEV 155
>UniRef50_Q8DIA7 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=37; Bacteria|Rep:
Phosphoribosylformylglycinamidine synthase II -
Synechococcus elongatus (Thermosynechococcus elongatus)
Length = 761
Score = 43.6 bits (98), Expect = 0.037
Identities = 17/35 (48%), Positives = 24/35 (68%)
Query: 311 IIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVG 345
+ F E+HN P+A+ PF GA TG GG +RD+ +G
Sbjct: 87 LAFKIESHNHPSAIEPFQGAATGVGGILRDIFTMG 121
>UniRef50_Q67KF8 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=6; Bacteria|Rep: Phosphoribosylformylglycinamidine
synthase II - Symbiobacterium thermophilum
Length = 778
Score = 43.6 bits (98), Expect = 0.037
Identities = 21/53 (39%), Positives = 33/53 (62%), Gaps = 3/53 (5%)
Query: 296 VRGPSQ---VIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVG 345
++GP + V++ + + F E+HN P+ V PF+GA TG GG +RDV +G
Sbjct: 65 LQGPGENAGVVRIDDDLAVAFKLESHNHPSFVDPFNGAATGVGGILRDVFTMG 117
Score = 39.1 bits (87), Expect = 0.81
Identities = 49/238 (20%), Positives = 86/238 (36%), Gaps = 14/238 (5%)
Query: 729 GSATSIGTQNIKGLLDPAAGARLSLGEALTNLVFAGISELEDVKCSGNWMWAGKTGVEXX 788
G A S+ L+P G +++ EA N V G V + N + E
Sbjct: 475 GIAASVDCNGRYVYLNPRRGTAIAVAEAARNCVVTGA---RPVAITNNCNFGNPEKPEIF 531
Query: 789 -XXXXXXXXXXXXMRALGVAVDGGKDSLSMCAHVAGEKVKSPGTL-VVSTYAPCPDITVK 846
ALG V GG ++S +GE + T+ +++ + +T
Sbjct: 532 WTFDEAITGMAEACEALGTPVTGG--NVSFYNETSGEAIHPTPTIGMIAVHENLDRLTT- 588
Query: 847 IEPALKEENSALVHAPVSPGKYRLGGSALAQCYKQLGDNXXXXXXXXXXKSLFKITQKLL 906
P K+ ++ + + LGGS A+ + K L + + +
Sbjct: 589 --PGFKQVGDVILL--LGETRDELGGSEYARLIHGVLAGDAPALDLAFEKRLQDVVLRAI 644
Query: 907 KEKKLISGHDISEGGFITTVLEMGIGGVR-GLNLHVNVAANVSPIEA-LFNEELGIVL 962
E + + HD++EGG + EM I L V++ ++ LF E +L
Sbjct: 645 HEGLVTAAHDVAEGGLAVALAEMAIAAAEPSLGCQVSIFLGEGRVDGQLFGESQSRIL 702
Score = 35.9 bits (79), Expect = 7.5
Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 5/109 (4%)
Query: 507 VVRGCLES-DVNPVESIHDQGAGGNGNVLKELVEPEGAVVF--TKEFQLGDPTITTLELW 563
++ CLE + + V I D GA G + E+ G V ++ + + E
Sbjct: 247 LMEACLELFETDAVVGIQDMGAAGLISSSSEMAARGGVGVELDVRKVPAREEGMEPWEFL 306
Query: 564 GAEYQENDALLCSKANRHI-LEEICRRERCPVSFVGEVTGDGYMSLIED 611
+E QE L+C K R +E ICR+ + +G VT DG + +++D
Sbjct: 307 LSESQER-MLVCVKKGREAEVEAICRKWGVGCAVIGRVTDDGMVRVLDD 354
>UniRef50_Q57DR8 Cluster: Phosphoribosylformylglycinamidine synthase
2; n=73; Bacteria|Rep: Phosphoribosylformylglycinamidine
synthase 2 - Brucella abortus
Length = 740
Score = 43.6 bits (98), Expect = 0.037
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 3/56 (5%)
Query: 293 PTNVRGPSQ---VIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVG 345
P ++GP + V+ ++F E+HN P+ + P+ GA TG GG +RDV +G
Sbjct: 68 PRVIQGPGENAGVVDIGDGDCVVFKMESHNHPSYIEPYQGAATGVGGILRDVFTMG 123
>UniRef50_A3VSU9 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=9; Alphaproteobacteria|Rep:
Phosphoribosylformylglycinamidine synthase II -
Parvularcula bermudensis HTCC2503
Length = 911
Score = 43.2 bits (97), Expect = 0.050
Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
Query: 293 PTNVRGPSQ---VIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVG 345
P + GP + V+ ++F E+HN P+ + P+ GA TG GG +RDV +G
Sbjct: 63 PQVIHGPGENAGVVDIGDGQAVVFKMESHNHPSFIEPYQGAATGVGGIMRDVFTMG 118
>UniRef50_A5NUY4 Cluster: Phosphoribosylformylglycinamidine
synthase; n=1; Methylobacterium sp. 4-46|Rep:
Phosphoribosylformylglycinamidine synthase -
Methylobacterium sp. 4-46
Length = 819
Score = 41.9 bits (94), Expect = 0.11
Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
Query: 293 PTNVRGPSQ---VIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVG 345
P ++GP + VI +F E+HN P+ + P+ GA TG GG +RDV +G
Sbjct: 124 PWVIQGPGENAGVIDIGDGRACVFKMESHNHPSFIEPYQGAATGVGGILRDVFTMG 179
>UniRef50_A3EVN2 Cluster: Phosphoribosylformylglycinamidine
synthase, synthetase domain; n=1; Leptospirillum sp.
Group II UBA|Rep: Phosphoribosylformylglycinamidine
synthase, synthetase domain - Leptospirillum sp. Group
II UBA
Length = 737
Score = 41.5 bits (93), Expect = 0.15
Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
Query: 311 IIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVGRGGHTVAGTAGYSVGNLHIP 365
+ F E+HN P+ + PF G+ TG GG +RDV + G VA G+L P
Sbjct: 80 LAFKMESHNHPSFLEPFQGSATGVGGILRDV--IAMGARPVALANSLVFGSLRHP 132
>UniRef50_Q8FMM3 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=16; Actinomycetales|Rep:
Phosphoribosylformylglycinamidine synthase II -
Corynebacterium efficiens
Length = 763
Score = 41.5 bits (93), Expect = 0.15
Identities = 16/35 (45%), Positives = 22/35 (62%)
Query: 311 IIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVG 345
+ F E+HN P+ V P GA TG GG +RD+ +G
Sbjct: 102 VTFRVESHNHPSFVEPHQGAATGIGGIVRDIMAMG 136
>UniRef50_Q1VJ60 Cluster: Phosphoribosylformylglycinamidine synthase I
(FGAM) synthase; n=1; Psychroflexus torquis ATCC
700755|Rep: Phosphoribosylformylglycinamidine synthase I
(FGAM) synthase - Psychroflexus torquis ATCC 700755
Length = 66
Score = 40.7 bits (91), Expect = 0.26
Identities = 18/31 (58%), Positives = 22/31 (70%)
Query: 1269 YPMNPNGSPDGLAGVRSRDGRHIAMMPHPER 1299
Y NPNGS + +AGV S + R + MMPHPER
Sbjct: 11 YCNNPNGSIEDIAGVLSSNRRVLGMMPHPER 41
>UniRef50_A0B5C7 Cluster: Phosphoribosylformylglycinamidine synthase
II; n=1; Methanosaeta thermophila PT|Rep:
Phosphoribosylformylglycinamidine synthase II -
Methanosaeta thermophila (strain DSM 6194 / PT)
(Methanothrixthermophila (strain DSM 6194 / PT))
Length = 768
Score = 40.7 bits (91), Expect = 0.26
Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
Query: 293 PTNVRGPSQ---VIQKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGVG 345
P V GP + ++ E ++ + E+HN P+ + P GA TG GG +RDV +G
Sbjct: 72 PNVVLGPVEDAGIVSIDDEWCVVISHESHNHPSQILPNEGAATGIGGIVRDVNCMG 127
Score = 37.9 bits (84), Expect = 1.9
Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 4/125 (3%)
Query: 842 DITVKIEPALKEENSALVHAPVSPGKYRLGGSALAQC-YKQLGDNXXXXXXXXXXKSLFK 900
DI+ I +LKE L + P LGGS + + G N ++
Sbjct: 588 DISRAITMSLKEAGDGLYL--LGPRFDELGGSEYYRLIWGVTGANVPVVRFPLERSMIYT 645
Query: 901 ITQKLLKEKKLISGHDISEGGFITTVLEMGIGGVRGLNLHVNVAANVSPIEALFNEELGI 960
+ + +E L + HDIS GG T EM + G+++ ++ ++ + LF+E G
Sbjct: 646 VIDAVDREI-LRAAHDISNGGMAITAAEMCMLSDHGISIDISDLGDMRSDKLLFSESSGF 704
Query: 961 VLEVS 965
V+EV+
Sbjct: 705 VVEVA 709
>UniRef50_Q2J4Z5 Cluster: DEAD/DEAH box helicase-like; n=3;
Frankia|Rep: DEAD/DEAH box helicase-like - Frankia sp.
(strain CcI3)
Length = 804
Score = 38.7 bits (86), Expect = 1.1
Identities = 25/62 (40%), Positives = 32/62 (51%), Gaps = 6/62 (9%)
Query: 1270 PMNPNGSPDGLAGVRSRDGRHIAMMPHPERCVLRWQCPAPCPTVTNPSVRN-----SQAS 1324
P++ +G+ LAG+R RD R M H ER R CPAP P +P +R AS
Sbjct: 26 PVDVDGADTVLAGLR-RDVRRARCMTHIERVPARDGCPAPWPDWIDPVLRGRWTAAGIAS 84
Query: 1325 PW 1326
PW
Sbjct: 85 PW 86
>UniRef50_Q0LR46 Cluster: Putative uncharacterized protein; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep: Putative
uncharacterized protein - Herpetosiphon aurantiacus ATCC
23779
Length = 255
Score = 37.5 bits (83), Expect = 2.5
Identities = 26/71 (36%), Positives = 40/71 (56%), Gaps = 3/71 (4%)
Query: 212 LFVN-KLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGK-EINESLIDMVASTQKTSN 269
LF+N ++D V+L ++ SNSE S+ F G L + INE++++ + T TS
Sbjct: 127 LFLNDSTQKDILDVKLINIMTSNSESSKLEIFSGYLYCNSSIGINENVLNDIFITTATSM 186
Query: 270 NNNVIKFGDNS 280
NN V K D+S
Sbjct: 187 NNEV-KITDSS 196
>UniRef50_A7GWE3 Cluster: Transcription termination factor; n=1;
Campylobacter curvus 525.92|Rep: Transcription
termination factor - Campylobacter curvus 525.92
Length = 1081
Score = 37.5 bits (83), Expect = 2.5
Identities = 51/194 (26%), Positives = 80/194 (41%), Gaps = 17/194 (8%)
Query: 937 LNLHVNVAANVSPIEALFNEELGIVLEVSKNDLPYVLSEYNNNGVGAQHIGYTGKYGMDS 996
LN +N A V +E L V ND+ Y +S N + GK+ DS
Sbjct: 137 LNFALNTAKIVKGSFGYSDENLTHPFNVKFNDINYEISGINTE------LNSIGKHSFDS 190
Query: 997 -----QVVINLNGVNVLDTVLIDVFRMWEETSYRLECLQANTDCVLQEWKVLEKRKGATY 1051
Q + GV++ + V ++ E S + + D LQ ++ K Y
Sbjct: 191 NSSLAQKIDWQGGVDISPLRIYGVLKI-NEFSIKPVAISFIDDQSLQIKNMIIDTK-LDY 248
Query: 1052 NVTFDPTAAVIKTKSIKVAVLREEGINGDREM-IASLMLANFDVFDVTMSDLQNKKITLD 1110
+ D A IK K + + E + ++ M + L + N VFD T+SD ++ K+ LD
Sbjct: 249 ELAADKNATSIKLKDSFLTLKALEAVLENQNMKFSELSIPNI-VFDATISDKRDLKLNLD 307
Query: 1111 --AFQGVVFPGGFS 1122
A + F GG S
Sbjct: 308 TIALKEPSFEGGVS 321
>UniRef50_UPI0001509D30 Cluster: hypothetical protein
TTHERM_00657540; n=1; Tetrahymena thermophila SB210|Rep:
hypothetical protein TTHERM_00657540 - Tetrahymena
thermophila SB210
Length = 278
Score = 37.1 bits (82), Expect = 3.3
Identities = 16/50 (32%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
Query: 806 VAVDGGKDSLSMCAHVAGEKVKSPGTLVVSTYAPCPDITVKIEPALKEEN 855
V +DG K SL C H+A +P +++ +AP PD +I+ +++N
Sbjct: 163 VGIDGSKKSLK-CLHIAASLANNPNDKLIACFAPSPDRIKQIDEINQKQN 211
>UniRef50_Q9RXF2 Cluster: Competence protein ComEC/Rec2-related
protein; n=2; Deinococcus|Rep: Competence protein
ComEC/Rec2-related protein - Deinococcus radiodurans
Length = 275
Score = 37.1 bits (82), Expect = 3.3
Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 490 FGAVQRGDAEMGNRLNRVV--RGCLESDVNPVESIHDQGAGGNGNVLKELVEPEGAVVFT 547
F A+ GD+E L V R + V +SIH A G+ +V+PE V+
Sbjct: 168 FAALMTGDSETKETLAWVAERRPEIRGPVQVYKSIHHGAANGDHQAWFNVVKPENVVISV 227
Query: 548 KEFQLGDPTITTLELWGAEYQEND 571
E G PT L+L YQ+N+
Sbjct: 228 GENNYGHPTQAALDL----YQKNN 247
>UniRef50_Q2SQ63 Cluster: Uncharacterized protein conserved in
bacteria; n=1; Hahella chejuensis KCTC 2396|Rep:
Uncharacterized protein conserved in bacteria - Hahella
chejuensis (strain KCTC 2396)
Length = 243
Score = 36.7 bits (81), Expect = 4.3
Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 6/126 (4%)
Query: 615 EKFLDRSERLKLESKSKLPYDLHLEAVLGNMPRKTFDLQTEKRTKLPLSFPKDITVKSAL 674
++F ++S+RL + D E V+ T D Q + + + + KD + +
Sbjct: 82 DRFFEKSKRLLMNLLEARSLD---EVVIVLEDSFTGDFQVDFCSLVLFAEHKDFPISNVS 138
Query: 675 DRVLRLVNVASKRYLTNKVDRCVTGLVAQQ-QCVGPL-HTPLADCAIIALSYYDLVGSAT 732
L + A L N V L A+Q Q + P H +A CA+I L Y DL+G
Sbjct: 139 TASLMECSDALGEELLNSVKAVCGNLEARQLQVLFPHNHADIASCAVIPLRYGDLLG-ML 197
Query: 733 SIGTQN 738
SIG++N
Sbjct: 198 SIGSRN 203
>UniRef50_A7DQ22 Cluster: Putative uncharacterized protein
precursor; n=1; Candidatus Nitrosopumilus maritimus
SCM1|Rep: Putative uncharacterized protein precursor -
Candidatus Nitrosopumilus maritimus SCM1
Length = 573
Score = 36.7 bits (81), Expect = 4.3
Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
Query: 220 DPTSVELFDLAQSNSEHS-RHWFFKGKLVLDGKEINESLI--DMVASTQKT--SNNNNVI 274
DP +L + SE + H + +++ DGK+I L D+ T KT N+N +
Sbjct: 56 DPERYITINLKNAKSEAAVEHVTYAFEMIKDGKQIFRKLFHDDLGNLTIKTIYDNSNEIK 115
Query: 275 KFGDNSSAIKGFQHTILRPTNVRGP 299
GD S AI+ + T P + GP
Sbjct: 116 VIGDKSPAIESWMRTATEPVIMTGP 140
>UniRef50_Q97J06 Cluster: Predicted dehydrogenase; n=1; Clostridium
acetobutylicum|Rep: Predicted dehydrogenase - Clostridium
acetobutylicum
Length = 320
Score = 36.3 bits (80), Expect = 5.7
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
Query: 926 VLEMGIGGVRGLNLHVNVAANVSPIEALFNEEL--GIVLEVSKNDLPYVLSEYNNNGVGA 983
+ E IG VR L A +P LFN+EL G +L+V + Y + N+
Sbjct: 140 ISEGRIGEVRLLQADFGFKAEFNPDGRLFNKELGGGALLDVGIYTISYSSFVFGNHPRSI 199
Query: 984 QHIGYTGKYGMDSQVVINL 1002
+ Y GK G+D V INL
Sbjct: 200 KSNFYIGKTGIDECVSINL 218
>UniRef50_A1FJG1 Cluster: Sodium/hydrogen exchanger precursor; n=11;
Gammaproteobacteria|Rep: Sodium/hydrogen exchanger
precursor - Pseudomonas putida W619
Length = 608
Score = 36.3 bits (80), Expect = 5.7
Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 7/93 (7%)
Query: 1057 PTAAVIKTKSIKVAVLREEGINGDREMIASLMLANFDVFDVTMSDLQNKKITLDAFQGVV 1116
P V++ K+ +LR EGI D I +L+ F + +D +L F GV+
Sbjct: 137 PMLRVVRPKATIANILRWEGIVIDP--IGALLAVVVYSFIIASTDGNGLSQSLGTFAGVI 194
Query: 1117 FPGGFSYADTLGSAKGWAAGILFSESLSSQFAH 1149
F G LG+A GW G + E ++ H
Sbjct: 195 FCGS-----ALGAAGGWLLGQIMREQWLPEYLH 222
>UniRef50_A3TL52 Cluster: VCBS; n=1; Janibacter sp. HTCC2649|Rep: VCBS
- Janibacter sp. HTCC2649
Length = 2343
Score = 35.9 bits (79), Expect = 7.5
Identities = 34/127 (26%), Positives = 55/127 (43%), Gaps = 12/127 (9%)
Query: 237 SRHWFFKGKLVLDGKEINESLIDMV--ASTQKTSNNNNVIKFGDNSSAIKGFQHTILRPT 294
S+ W+ + V G +E+ D + A T + + + GDN+S G +
Sbjct: 1406 SQVWYVRNNAVAGGDGTSEAPFDTLGEAETAADAGDTTYVFDGDNTSLNLGSGFVMAAGE 1465
Query: 295 NVRGPSQVIQKKTESDIIFTAETHNMPTA------VAPFSGATTGTGGRIRDVQGVGRGG 348
+ G + +Q +D+++T N PT V + ATT G ++ D QG G GG
Sbjct: 1466 RLLGEAVTLQ--VGADVLYTGVPANRPTLTANDEDVVTLANATTVRGVQL-DPQGAG-GG 1521
Query: 349 HTVAGTA 355
GTA
Sbjct: 1522 IAGIGTA 1528
>UniRef50_A5AHS1 Cluster: Putative uncharacterized protein; n=2;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 1410
Score = 35.9 bits (79), Expect = 7.5
Identities = 30/101 (29%), Positives = 43/101 (42%), Gaps = 9/101 (8%)
Query: 244 GKLVLDGKEINESLIDMVASTQKTSNNNNVIKFGDNSSAIKGFQHTILRPTNVRGPSQVI 303
G V D K IN L + S + T N D S I Q+TI R TN+ +
Sbjct: 73 GDFVRDQKSINAQLNQRIDSVESTLNKRIDKMQNDLSWKIDNVQYTISRLTNL----NTV 128
Query: 304 QKKTESDIIFTAETHNMPTAVAPFSGATTGTGGRIRDVQGV 344
QKK + F ++ H P + A G ++R+V+ V
Sbjct: 129 QKKGK----FPSQPHQNPKGIHEVE-AQEGESSKVREVKAV 164
>UniRef50_Q8S8A7 Cluster: Predicted protein; n=1; Arabidopsis
thaliana|Rep: Predicted protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 469
Score = 35.5 bits (78), Expect = 9.9
Identities = 42/197 (21%), Positives = 79/197 (40%), Gaps = 11/197 (5%)
Query: 160 NLPRKSFNEGLPKDLEPWFVVPLQE---QGISAMRKVNDKLGLAF-----DTWDMEFYMD 211
N+ K +G D+ W+V L + + + +++ + L F D D +YM
Sbjct: 108 NVNAKINFQGTSYDVPAWYVSILPDCKTESYNTAKRMKLRTSLRFKNVSNDESDFLWYMT 167
Query: 212 LFVNKLKRDPTSVELFDLAQSNSEHSRHWFFKGKLVLDGKEINESLIDMVASTQKTSNNN 271
VN ++DP + L +++ H H F G+ + + N + K +
Sbjct: 168 T-VNLKEQDPAWGKNMSLRINSTAHVLHGFVNGQHTGNYRVENGKFHYVFEQDAKFNPGV 226
Query: 272 NVIKFGDNSSAIKGFQHTILR-PTNVRGPSQVIQKKTESDIIFTAETHNMPTAVAPFSGA 330
NVI + + + P + GP +I + + ++ THN T + F A
Sbjct: 227 NVITLLSVTVDLPNYGAFFENVPAGITGPVFIIGRNGDETVVKYLSTHNGATKLTIFK-A 285
Query: 331 TTGTGGRIRDVQGVGRG 347
G+ + D+ G G+G
Sbjct: 286 PLGSEPVVVDLLGFGKG 302
>UniRef50_A5DJ97 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 970
Score = 35.5 bits (78), Expect = 9.9
Identities = 15/46 (32%), Positives = 26/46 (56%)
Query: 665 PKDITVKSALDRVLRLVNVASKRYLTNKVDRCVTGLVAQQQCVGPL 710
P TV S ++ ++LV +YL++ D C+ GLV +C+ P+
Sbjct: 767 PSFKTVSSGIEAEIQLVLTFINQYLSHPKDSCIVGLVQYLRCIAPV 812
>UniRef50_A3CSW3 Cluster: Cobalt transport protein CbiN precursor;
n=1; Methanoculleus marisnigri JR1|Rep: Cobalt transport
protein CbiN precursor - Methanoculleus marisnigri
(strain ATCC 35101 / DSM 1498 / JR1)
Length = 99
Score = 35.5 bits (78), Expect = 9.9
Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
Query: 344 VGRGGHTVAGTAGYSVGNLHIPGYDLPWEEKGWEYPSNFATPLQIIIEASNGASDYGNKF 403
+G G G G + G + GY+ PW E WE PS L ++A+ GA G F
Sbjct: 31 LGDGEEAWGGADGEAAGLIEDSGYE-PWIEPFWEPPSGEIESLLFALQAAIGAVIIGYIF 89
Query: 404 G 404
G
Sbjct: 90 G 90
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.317 0.135 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,481,099,362
Number of Sequences: 1657284
Number of extensions: 64529135
Number of successful extensions: 154473
Number of sequences better than 10.0: 152
Number of HSP's better than 10.0 without gapping: 132
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 153560
Number of HSP's gapped (non-prelim): 392
length of query: 1340
length of database: 575,637,011
effective HSP length: 110
effective length of query: 1230
effective length of database: 393,335,771
effective search space: 483802998330
effective search space used: 483802998330
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 78 (35.5 bits)
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