Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000387-TA|BGIBMGA000387-PA|IPR001611|Leucine-rich
repeat, IPR002126|Cadherin, IPR000225|Armadillo,
IPR003591|Leucine-rich repeat, typical subtype
(2095 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precur... 149 1e-34
BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N, pol... 149 1e-34
BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N, pol... 149 1e-34
BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein. 148 2e-34
BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat con... 148 2e-34
AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein. 147 3e-34
BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat tra... 134 3e-30
BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat tra... 134 3e-30
AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat tra... 134 3e-30
AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein. 134 3e-30
AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein. 123 8e-27
AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein. 123 8e-27
AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens ... 123 8e-27
BC131897-1|AAI31898.1| 420|Homo sapiens LRRC4B protein protein. 122 1e-26
BC032460-1|AAH32460.1| 634|Homo sapiens Unknown (protein for IM... 122 1e-26
BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth fac... 121 3e-26
M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth facto... 120 4e-26
AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like ... 120 4e-26
AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit pro... 120 4e-26
Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V p... 116 9e-25
L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane glycopr... 116 9e-25
BC117276-1|AAI17277.1| 420|Homo sapiens reticulon 4 receptor-li... 116 1e-24
BC113673-1|AAI13674.1| 420|Homo sapiens reticulon 4 receptor-li... 116 1e-24
AF532858-1|AAP21835.1| 420|Homo sapiens Nogo-66 receptor homolo... 116 1e-24
AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich repeat-con... 116 1e-24
BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein. 115 2e-24
BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein. 115 2e-24
BC035133-1|AAH35133.1| 708|Homo sapiens leucine rich repeat neu... 114 4e-24
AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple recept... 114 4e-24
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 113 6e-24
AY250221-1|AAP82838.1| 420|Homo sapiens nogo receptor-like 3 pr... 113 6e-24
CR457397-1|CAG33678.1| 708|Homo sapiens LRRN3 protein. 113 9e-24
AY358280-1|AAQ88647.1| 708|Homo sapiens LRRN3 protein. 113 9e-24
AF134481-1|AAP97258.1| 708|Homo sapiens leucine-rich repeat pro... 113 9e-24
AB060967-1|BAB47184.1| 708|Homo sapiens neuronal leucine-rich r... 113 9e-24
DQ084201-1|AAY86708.1| 640|Homo sapiens netrin-G1 ligand splice... 112 1e-23
BC110058-1|AAI10059.1| 518|Homo sapiens leucine rich repeat tra... 111 3e-23
BC099738-1|AAH99738.1| 518|Homo sapiens leucine rich repeat tra... 111 3e-23
BC098301-1|AAH98301.1| 519|Homo sapiens LRRTM4 protein protein. 111 3e-23
BC098267-1|AAH98267.1| 519|Homo sapiens LRRTM4 protein protein. 111 3e-23
AY358324-1|AAQ88690.1| 590|Homo sapiens GFHL3075 protein. 111 3e-23
AY182030-1|AAO67551.1| 518|Homo sapiens leucine-rich repeat tra... 111 3e-23
AK126961-1|BAC86764.1| 518|Homo sapiens protein ( Homo sapiens ... 111 3e-23
BC041374-1|AAH41374.3| 640|Homo sapiens LRRC4C protein protein. 111 3e-23
AY358293-1|AAQ88660.1| 640|Homo sapiens LNKM292 protein. 111 3e-23
AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled recep... 111 3e-23
AB046800-1|BAB13406.1| 640|Homo sapiens KIAA1580 protein protein. 111 3e-23
BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich repeat-con... 109 8e-23
BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich repeat-con... 109 8e-23
AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-couple... 109 8e-23
AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled recep... 109 1e-22
AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich repeat-con... 107 3e-22
AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein. 107 3e-22
BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein. 107 6e-22
BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich repeat-con... 106 7e-22
AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor p... 106 7e-22
AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich repeat-con... 106 7e-22
BC111745-1|AAI11746.1| 653|Homo sapiens leucine rich repeat con... 105 1e-21
BC111561-1|AAI11562.1| 653|Homo sapiens leucine rich repeat con... 105 1e-21
AY358307-1|AAQ88674.1| 653|Homo sapiens NAG14 protein. 105 1e-21
AY182024-1|AAO67545.1| 522|Homo sapiens leucine-rich repeat tra... 105 1e-21
AK056644-1|BAB71240.1| 522|Homo sapiens protein ( Homo sapiens ... 105 1e-21
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L... 105 1e-21
AF196976-1|AAG28019.2| 653|Homo sapiens brain tumor associated ... 105 1e-21
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L... 105 1e-21
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 105 2e-21
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 105 2e-21
BC045113-1|AAH45113.1| 522|Homo sapiens LRRTM1 protein protein. 105 2e-21
AY358310-1|AAQ88677.1| 522|Homo sapiens DFLL675 protein. 105 2e-21
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 105 2e-21
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 105 2e-21
DQ084202-1|AAY86709.1| 640|Homo sapiens netrin-G1 ligand splice... 104 4e-21
BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein. 104 4e-21
CR456360-1|CAG30246.1| 473|Homo sapiens Em:AC007663.1 protein. 103 9e-21
BC011787-1|AAH11787.1| 473|Homo sapiens reticulon 4 receptor pr... 103 9e-21
AY358297-1|AAQ88664.1| 473|Homo sapiens NOGOR protein. 103 9e-21
AK172751-1|BAD18737.1| 653|Homo sapiens protein ( Homo sapiens ... 103 9e-21
AF283463-1|AAG53612.1| 473|Homo sapiens Nogo receptor protein. 103 9e-21
AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein. 102 2e-20
AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat neu... 102 2e-20
AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on chr... 102 2e-20
BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat neu... 101 3e-20
BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat neu... 101 3e-20
AL159161-1|CAI17102.1| 754|Homo sapiens relaxin/insulin-like fa... 101 3e-20
AL138708-1|CAH73785.1| 754|Homo sapiens relaxin/insulin-like fa... 101 3e-20
AF453828-1|AAL73946.1| 754|Homo sapiens G protein-coupled recep... 101 3e-20
AF403384-1|AAL69324.2| 754|Homo sapiens LGR8 protein. 101 3e-20
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 101 4e-20
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 101 4e-20
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 101 4e-20
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 101 4e-20
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 101 4e-20
AY899851-1|AAX85199.1| 730|Homo sapiens LGR8.1 protein. 100 5e-20
AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein. 100 5e-20
AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat neu... 100 5e-20
AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens ... 100 5e-20
AJ297858-1|CAC82651.1| 649|Homo sapiens hypothetical protein pr... 100 6e-20
BC073974-1|AAH73974.1| 359|Homo sapiens chondroadherin protein. 97 6e-19
BC036360-1|AAH36360.1| 359|Homo sapiens chondroadherin protein. 97 6e-19
AF371328-1|AAK51556.1| 359|Homo sapiens chondroadherin protein. 97 6e-19
BC113717-1|AAI13718.1| 581|Homo sapiens leucine rich repeat tra... 97 8e-19
BC113715-1|AAI13716.1| 581|Homo sapiens leucine rich repeat tra... 97 8e-19
BC111492-1|AAI11493.1| 581|Homo sapiens leucine rich repeat tra... 97 8e-19
AY358315-1|AAQ88681.1| 513|Homo sapiens GFNV803 protein. 97 8e-19
AY182028-1|AAO67549.1| 513|Homo sapiens leucine-rich repeat tra... 97 8e-19
U96769-1|AAC13410.1| 359|Homo sapiens chondroadherin protein. 95 2e-18
BC034947-1|AAH34947.1| 716|Homo sapiens leucine rich repeat neu... 95 2e-18
AY358312-1|AAQ88679.1| 716|Homo sapiens NLRR protein. 95 3e-18
AB074161-1|BAE45733.1| 716|Homo sapiens neuronal leucine-rich r... 95 3e-18
AB040930-1|BAA96021.1| 730|Homo sapiens KIAA1497 protein protein. 95 3e-18
BC128608-1|AAI28609.1| 441|Homo sapiens reticulon 4 receptor-li... 94 4e-18
AY250219-1|AAP82836.1| 441|Homo sapiens nogo receptor-like 2 pr... 94 4e-18
AF532859-1|AAP21836.1| 441|Homo sapiens Nogo-66 receptor homolo... 94 4e-18
BC011057-1|AAH11057.2| 620|Homo sapiens leucine rich repeat and... 94 6e-18
AY324320-1|AAQ97216.1| 620|Homo sapiens leucine-rich repeat neu... 94 6e-18
AL834260-1|CAD38935.1| 577|Homo sapiens hypothetical protein pr... 94 6e-18
BC068558-1|AAH68558.1| 614|Homo sapiens LINGO1 protein protein. 93 7e-18
AY358284-1|AAQ88651.1| 620|Homo sapiens QVSK201 protein. 93 1e-17
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 92 2e-17
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 92 2e-17
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 92 2e-17
BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein. 92 2e-17
BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product p... 92 2e-17
AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein. 92 2e-17
AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein. 92 2e-17
AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein. 92 2e-17
BC068590-1|AAH68590.1| 778|Homo sapiens LOC150356 protein protein. 91 4e-17
BC040188-1|AAH40188.1| 692|Homo sapiens LOC150356 protein protein. 91 4e-17
AL035681-1|CAI22653.1| 762|Homo sapiens protein ( Human DNA seq... 91 4e-17
BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein. 91 5e-17
AY324323-1|AAQ97218.1| 479|Homo sapiens leucine-rich repeat neu... 91 5e-17
AL512424-2|CAI14256.1| 380|Homo sapiens slit homolog 1 (Drosoph... 89 1e-16
BC043165-1|AAH43165.1| 719|Homo sapiens leucine rich repeat and... 89 2e-16
AK055365-1|BAB70910.1| 719|Homo sapiens protein ( Homo sapiens ... 89 2e-16
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 88 3e-16
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 88 3e-16
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 88 3e-16
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 87 6e-16
AL356953-4|CAI15930.1| 828|Homo sapiens leucine-rich repeat-con... 86 1e-15
AF190501-1|AAG17168.1| 828|Homo sapiens leucine-rich repeat-con... 86 1e-15
BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich alpha-2-gl... 85 2e-15
AY029183-1|AAK31796.1| 798|Homo sapiens SLIT1 isoform B protein. 85 2e-15
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 85 2e-15
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 85 2e-15
AL512424-3|CAI14257.1| 409|Homo sapiens slit homolog 1 (Drosoph... 85 2e-15
AL512424-1|CAI14255.1| 782|Homo sapiens slit homolog 1 (Drosoph... 85 2e-15
AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 85 2e-15
AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 85 2e-15
AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich alpha-2-gl... 85 2e-15
BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like fa... 85 3e-15
BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich repeat-con... 85 3e-15
BC094737-1|AAH94737.1| 904|Homo sapiens toll-like receptor 3 pr... 85 3e-15
BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich alpha-2-gl... 85 3e-15
AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein. 85 3e-15
AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich alpha-2-gl... 85 3e-15
AF190500-1|AAG17167.1| 757|Homo sapiens leucine-rich repeat-con... 85 3e-15
AB208943-1|BAD92180.1| 627|Homo sapiens leucine-rich repeat-con... 85 3e-15
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 85 3e-15
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 85 3e-15
U88879-1|AAC34134.1| 904|Homo sapiens Toll-like receptor 3 prot... 84 5e-15
DQ445682-1|ABE01399.1| 904|Homo sapiens Toll-like receptor 3 is... 84 5e-15
BC096335-1|AAH96335.1| 904|Homo sapiens toll-like receptor 3 pr... 84 5e-15
BC096334-1|AAH96334.1| 904|Homo sapiens toll-like receptor 3 pr... 84 5e-15
BC096333-1|AAH96333.1| 904|Homo sapiens toll-like receptor 3 pr... 84 5e-15
BC059372-1|AAH59372.1| 870|Homo sapiens TLR3 protein protein. 84 5e-15
BC048421-1|AAH48421.1| 453|Homo sapiens LOC150356 protein protein. 84 5e-15
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 84 6e-15
BC126464-1|AAI26465.1| 1371|Homo sapiens erbb2 interacting prote... 82 2e-14
BC115015-1|AAI15016.1| 1367|Homo sapiens ERBB2IP protein protein. 82 2e-14
BC050692-1|AAH50692.1| 633|Homo sapiens ERBB2IP protein protein. 81 3e-14
AF276423-1|AAK69431.1| 1412|Homo sapiens densin-180-like protein... 81 3e-14
AF263744-1|AAF77048.1| 1371|Homo sapiens erbb2-interacting prote... 81 3e-14
AB033051-1|BAA86539.2| 1371|Homo sapiens KIAA1225 protein protein. 81 3e-14
AC108017-1|AAY41039.1| 260|Homo sapiens unknown protein. 81 6e-14
Z93015-1|CAI42364.1| 481|Homo sapiens nyctalopin protein. 80 7e-14
BC112242-1|AAI12243.1| 481|Homo sapiens nyctalopin protein. 80 7e-14
AJ278865-1|CAC19014.1| 481|Homo sapiens leucine-rich repeat pro... 80 7e-14
AF254868-1|AAG42685.1| 481|Homo sapiens nyctalopin protein. 80 7e-14
BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat con... 80 1e-13
BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein. 80 1e-13
AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat con... 80 1e-13
AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens ... 80 1e-13
X72913-1|CAA51418.1| 376|Homo sapiens fibromodulin protein. 79 1e-13
BC115012-1|AAI15013.1| 1371|Homo sapiens erbb2 interacting prote... 79 2e-13
BC018370-1|AAH18370.1| 674|Homo sapiens fibronectin leucine ric... 79 2e-13
AY358308-1|AAQ88675.1| 674|Homo sapiens FLRT1 protein. 79 2e-13
AF169675-1|AAF28459.1| 674|Homo sapiens leucine-rich repeat tra... 79 2e-13
BC035281-1|AAH35281.1| 376|Homo sapiens fibromodulin protein. 79 2e-13
AL359837-1|CAH73821.1| 376|Homo sapiens fibromodulin protein. 79 2e-13
AL391728-2|CAH73692.1| 1495|Homo sapiens leucine rich repeat con... 78 3e-13
AL391728-1|CAH73691.1| 1537|Homo sapiens leucine rich repeat con... 78 3e-13
AL359412-2|CAH74019.1| 1495|Homo sapiens leucine rich repeat con... 78 3e-13
AL359412-1|CAH74018.1| 1537|Homo sapiens leucine rich repeat con... 78 3e-13
AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich repeat-con... 78 3e-13
AL158840-2|CAH70975.1| 1495|Homo sapiens leucine rich repeat con... 78 3e-13
AL158840-1|CAH70974.1| 1537|Homo sapiens leucine rich repeat con... 78 3e-13
AL157948-2|CAI22426.1| 1495|Homo sapiens leucine rich repeat con... 78 3e-13
AL157948-1|CAI22425.1| 1537|Homo sapiens leucine rich repeat con... 78 3e-13
AL117353-1|CAI23423.1| 1495|Homo sapiens leucine rich repeat con... 78 3e-13
AF434715-1|AAL28133.1| 1537|Homo sapiens densin-180 protein. 78 3e-13
BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein. 78 4e-13
AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein. 78 4e-13
AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein. 78 4e-13
AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein. 78 4e-13
AL445183-4|CAH72591.1| 661|Homo sapiens podocan protein. 78 4e-13
BC063114-1|AAH63114.1| 384|Homo sapiens ASPN protein protein. 77 7e-13
AY358329-1|AAQ88695.1| 379|Homo sapiens ASPN protein. 77 7e-13
AY029191-1|AAK31800.1| 381|Homo sapiens periodontal ligament as... 77 7e-13
AL137848-5|CAI16697.1| 380|Homo sapiens asporin (LRR class 1) p... 77 7e-13
AF316824-1|AAK35161.1| 379|Homo sapiens asporin precursor protein. 77 7e-13
BC114621-1|AAI14622.1| 977|Homo sapiens SLIT and NTRK-like fami... 76 1e-12
BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like fami... 76 1e-12
AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein. 76 1e-12
AB020655-1|BAA74871.2| 988|Homo sapiens KIAA0848 protein protein. 76 1e-12
U21128-1|AAA91639.1| 338|Homo sapiens lumican protein. 76 2e-12
U18728-1|AAA85268.1| 338|Homo sapiens lumican protein. 76 2e-12
BT006707-1|AAP35353.1| 338|Homo sapiens lumican protein. 76 2e-12
BC035997-1|AAH35997.1| 338|Homo sapiens lumican protein. 76 2e-12
BC007038-1|AAH07038.1| 338|Homo sapiens lumican protein. 76 2e-12
AY358115-1|AAQ88482.1| 593|Homo sapiens DAAT9248 protein. 76 2e-12
AL589765-16|CAI17178.1| 593|Homo sapiens leucine rich repeat ne... 76 2e-12
AK223177-1|BAD96897.1| 338|Homo sapiens lumican variant protein. 76 2e-12
BC020870-1|AAH20870.1| 649|Homo sapiens fibronectin leucine ric... 75 2e-12
BC016048-1|AAH16048.1| 317|Homo sapiens LRRC38 protein protein. 75 2e-12
AY358319-1|AAQ88685.1| 649|Homo sapiens FLRT3 protein. 75 2e-12
AL603749-2|CAH70436.1| 294|Homo sapiens leucine rich repeat con... 75 2e-12
AL354712-1|CAI21926.1| 294|Homo sapiens leucine rich repeat con... 75 2e-12
AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of cle... 75 2e-12
AL132826-1|CAB86687.1| 649|Homo sapiens fibronectin leucine ric... 75 2e-12
AK095610-1|BAC04589.1| 370|Homo sapiens protein ( Homo sapiens ... 75 2e-12
AK074909-1|BAC11284.1| 649|Homo sapiens protein ( Homo sapiens ... 75 2e-12
AK074883-1|BAC11265.1| 627|Homo sapiens protein ( Homo sapiens ... 75 2e-12
AK027694-1|BAB55303.1| 623|Homo sapiens protein ( Homo sapiens ... 75 2e-12
AK027297-1|BAB55023.1| 649|Homo sapiens protein ( Homo sapiens ... 75 2e-12
AF169677-1|AAF28461.1| 649|Homo sapiens leucine-rich repeat tra... 75 2e-12
AB040902-1|BAA95993.1| 662|Homo sapiens KIAA1469 protein protein. 75 2e-12
M14219-1|AAB00774.1| 359|Homo sapiens proteoglycan core protein... 75 3e-12
CR541946-1|CAG46744.1| 359|Homo sapiens DCN protein. 75 3e-12
CR407676-1|CAG28604.1| 359|Homo sapiens DCN protein. 75 3e-12
BT019800-1|AAV38603.1| 359|Homo sapiens decorin protein. 75 3e-12
BC130290-1|AAI30291.1| 660|Homo sapiens fibronectin leucine ric... 75 3e-12
BC126249-1|AAI26250.1| 660|Homo sapiens fibronectin leucine ric... 75 3e-12
BC005322-1|AAH05322.1| 359|Homo sapiens decorin protein. 75 3e-12
AY358287-1|AAQ88654.1| 660|Homo sapiens FLRT2 protein. 75 3e-12
AF491944-1|AAL92176.1| 359|Homo sapiens decorin protein. 75 3e-12
AF169676-1|AAF28460.1| 660|Homo sapiens leucine-rich repeat tra... 75 3e-12
AF138300-1|AAD44713.1| 359|Homo sapiens decorin variant A protein. 75 3e-12
AB007865-1|BAA23701.2| 706|Homo sapiens KIAA0405 protein. 75 3e-12
AK001991-1|BAA92025.1| 273|Homo sapiens protein ( Homo sapiens ... 75 4e-12
J04599-1|AAA36009.1| 368|Homo sapiens protein ( Human hPGI mRNA... 73 1e-11
BT007323-1|AAP35987.1| 368|Homo sapiens biglycan protein. 73 1e-11
BC004244-1|AAH04244.1| 368|Homo sapiens biglycan protein. 73 1e-11
BC002416-1|AAH02416.1| 368|Homo sapiens biglycan protein. 73 1e-11
AK223302-1|BAD97022.1| 368|Homo sapiens biglycan preproprotein ... 73 1e-11
AK222484-1|BAD96204.1| 368|Homo sapiens biglycan preproprotein ... 73 1e-11
M65085-1|AAA52477.1| 695|Homo sapiens follicle stimulating horm... 73 1e-11
BC109118-1|AAI09119.1| 858|Homo sapiens TLR5 protein protein. 73 1e-11
BC103509-1|AAI03510.1| 958|Homo sapiens SLIT and NTRK-like fami... 73 1e-11
BC098287-1|AAH98287.1| 958|Homo sapiens SLIT and NTRK-like fami... 73 1e-11
BC098106-1|AAH98106.1| 958|Homo sapiens SLIT and NTRK-like fami... 73 1e-11
BC033651-1|AAH33651.1| 1049|Homo sapiens toll-like receptor 7 pr... 73 1e-11
AY358292-1|AAQ88659.1| 1049|Homo sapiens TLR7 protein. 73 1e-11
AL929091-1|CAM28378.1| 858|Homo sapiens toll-like receptor 5 pr... 73 1e-11
AL603883-1|CAH73026.1| 958|Homo sapiens SLIT and NTRK-like fami... 73 1e-11
AF240467-1|AAF60188.1| 1049|Homo sapiens toll-like receptor 7 pr... 73 1e-11
AF051151-1|AAC34376.1| 858|Homo sapiens Toll/interleukin-1 rece... 73 1e-11
AB060695-1|BAB43955.1| 858|Homo sapiens Toll-like receptor 5 pr... 73 1e-11
AB020725-1|BAA74941.1| 966|Homo sapiens KIAA0918 protein protein. 73 1e-11
L01131-1|AAA52301.1| 347|Homo sapiens decorin protein. 72 2e-11
AL591063-1|CAI15264.1| 789|Homo sapiens RP11-535K1.2 protein. 72 2e-11
AB033072-1|BAA86560.1| 832|Homo sapiens KIAA1246 protein protein. 72 2e-11
AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein. 72 2e-11
BC109119-1|AAI09120.1| 858|Homo sapiens TLR5 protein protein. 72 3e-11
S59900-1|AAB26480.1| 695|Homo sapiens follicle stimulating horm... 71 3e-11
M95489-1|AAA52478.1| 695|Homo sapiens follicle stimulating horm... 71 3e-11
BC118548-1|AAI18549.1| 695|Homo sapiens follicle stimulating ho... 71 3e-11
BC096831-1|AAH96831.1| 695|Homo sapiens follicle stimulating ho... 71 3e-11
BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of cle... 71 3e-11
AY429104-1|AAR07899.1| 695|Homo sapiens follicle stimulating ho... 71 3e-11
AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of cle... 71 3e-11
AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR... 71 3e-11
AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat pro... 71 3e-11
BC071866-1|AAH71866.1| 460|Homo sapiens Unknown (protein for IM... 71 4e-11
BC015581-1|AAH15581.2| 635|Homo sapiens leucine rich repeat and... 71 4e-11
BC007718-1|AAH07718.1| 541|Homo sapiens LRFN4 protein protein. 71 4e-11
AL713693-1|CAD28493.1| 689|Homo sapiens hypothetical protein pr... 71 4e-11
AK057619-1|BAB71535.1| 469|Homo sapiens protein ( Homo sapiens ... 71 4e-11
AB209005-1|BAD92242.1| 622|Homo sapiens leucine rich repeat and... 71 4e-11
Y19205-1|CAC80724.1| 845|Homo sapiens SLITL1 protein. 71 6e-11
BC113012-1|AAI13013.1| 845|Homo sapiens SLIT and NTRK-like fami... 71 6e-11
BC113011-1|AAI13012.1| 845|Homo sapiens SLIT and NTRK-like fami... 71 6e-11
AY358828-1|AAQ89187.1| 733|Homo sapiens LSGV9197 protein. 71 6e-11
AL109653-2|CAC18888.1| 845|Homo sapiens SLIT and NTRK-like fami... 71 6e-11
AL109653-1|CAI41645.1| 724|Homo sapiens SLIT and NTRK-like fami... 71 6e-11
AK091015-1|BAC03566.1| 724|Homo sapiens protein ( Homo sapiens ... 71 6e-11
AF245702-1|AAF78035.1| 1049|Homo sapiens toll-like receptor 7 pr... 71 6e-11
AB058757-1|BAB47483.1| 572|Homo sapiens KIAA1854 protein protein. 71 6e-11
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 70 8e-11
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 70 8e-11
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 70 8e-11
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 70 8e-11
M65153-1|AAA52287.1| 394|Homo sapiens biglycan protein. 70 1e-10
BC035645-1|AAH35645.1| 1266|Homo sapiens Similar to RIKEN cDNA 3... 70 1e-10
BC028292-1|AAH28292.1| 402|Homo sapiens PODN protein protein. 70 1e-10
AY358306-1|AAQ88673.1| 616|Homo sapiens GPR125 protein. 70 1e-10
BC101073-1|AAI01074.1| 841|Homo sapiens SLIT and NTRK-like fami... 69 2e-10
BC101072-1|AAI01073.1| 841|Homo sapiens SLIT and NTRK-like fami... 69 2e-10
BC101071-1|AAI01072.1| 841|Homo sapiens SLIT and NTRK-like fami... 69 2e-10
BC101070-1|AAI01071.1| 841|Homo sapiens SLIT and NTRK-like fami... 69 2e-10
BC080586-1|AAH80586.1| 743|Homo sapiens MXRA5 protein protein. 69 2e-10
BC064986-1|AAH64986.1| 743|Homo sapiens MXRA5 protein protein. 69 2e-10
BC011846-1|AAH11846.1| 743|Homo sapiens MXRA5 protein protein. 69 2e-10
BC003193-1|AAH03193.1| 524|Homo sapiens leucine rich repeat con... 69 2e-10
AL513211-1|CAI17358.1| 524|Homo sapiens leucine rich repeat con... 69 2e-10
AL033384-1|CAI21666.1| 524|Homo sapiens leucine rich repeat con... 69 2e-10
AK026427-1|BAB15480.1| 440|Homo sapiens protein ( Homo sapiens ... 69 2e-10
AF359380-1|AAK72246.1| 524|Homo sapiens LANO adaptor protein pr... 69 2e-10
AF332199-1|AAK69623.1| 524|Homo sapiens leucine-rich repeats pr... 69 2e-10
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 69 2e-10
BC003578-1|AAH03578.1| 628|Homo sapiens leucine rich repeat and... 69 2e-10
AK172834-1|BAD18799.1| 459|Homo sapiens protein ( Homo sapiens ... 69 2e-10
AK172754-1|BAD18740.1| 628|Homo sapiens protein ( Homo sapiens ... 69 2e-10
AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein. 69 2e-10
Z24680-1|CAA80847.1| 662|Homo sapiens garp protein. 68 3e-10
BC070079-1|AAH70079.1| 662|Homo sapiens LRRC32 protein protein. 68 3e-10
BC052210-1|AAH52210.2| 552|Homo sapiens LRRC32 protein protein. 68 3e-10
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 68 3e-10
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 68 3e-10
BC019687-1|AAH19687.1| 430|Homo sapiens LRRC4B protein protein. 68 4e-10
BC129927-1|AAI29928.1| 1323|Homo sapiens PH domain and leucine r... 67 6e-10
BC057786-1|AAH57786.1| 512|Homo sapiens podocan-like 1 protein. 67 6e-10
BC051738-1|AAH51738.1| 696|Homo sapiens SLIT and NTRK-like fami... 67 6e-10
BC040879-1|AAH40879.1| 493|Homo sapiens adhesion molecule with ... 67 6e-10
AY237007-1|AAO48948.1| 493|Homo sapiens transmembrane protein A... 67 6e-10
AL355145-6|CAI22942.1| 493|Homo sapiens adhesion molecule with ... 67 6e-10
AB032989-1|BAA86477.1| 437|Homo sapiens KIAA1163 protein protein. 67 6e-10
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 67 7e-10
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 67 7e-10
BC032713-1|AAH32713.1| 1032|Homo sapiens toll-like receptor 9 pr... 67 7e-10
AY359085-1|AAQ89443.1| 1032|Homo sapiens TLR9 protein. 67 7e-10
AY358289-1|AAQ88656.1| 696|Homo sapiens LLWI233 protein. 67 7e-10
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 67 7e-10
AY090637-1|AAM09084.1| 320|Homo sapiens tumor endothelial marke... 67 7e-10
AL355481-1|CAC37488.1| 696|Homo sapiens SLIT and NTRK-like fami... 67 7e-10
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 67 7e-10
AF259263-1|AAF72190.1| 975|Homo sapiens toll-like receptor 9 fo... 67 7e-10
AF259262-1|AAF72189.1| 1032|Homo sapiens toll-like receptor 9 fo... 67 7e-10
AF245704-1|AAF78037.1| 1032|Homo sapiens toll-like receptor 9 pr... 67 7e-10
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 67 7e-10
AB067497-1|BAB67803.1| 760|Homo sapiens KIAA1910 protein protein. 67 7e-10
AB045180-1|BAB19259.1| 1032|Homo sapiens toll-like receptor 9 pr... 67 7e-10
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 67 7e-10
U41344-1|AAC18782.1| 382|Homo sapiens prolargin protein. 66 2e-09
U29089-1|AAC50230.1| 382|Homo sapiens proline- arginine-rich en... 66 2e-09
D83597-1|BAA12019.1| 661|Homo sapiens RP105 protein. 66 2e-09
CR542270-1|CAG47066.1| 382|Homo sapiens PRELP protein. 66 2e-09
CR541787-1|CAG46586.1| 382|Homo sapiens PRELP protein. 66 2e-09
BC109070-1|AAI09071.1| 661|Homo sapiens CD180 molecule protein. 66 2e-09
BC109069-1|AAI09070.1| 661|Homo sapiens CD180 molecule protein. 66 2e-09
BC058935-1|AAH58935.1| 239|Homo sapiens LRRC57 protein protein. 66 2e-09
BC035267-1|AAH35267.1| 723|Homo sapiens PHLPPL protein protein. 66 2e-09
BC032498-1|AAH32498.1| 382|Homo sapiens proline/arginine-rich e... 66 2e-09
AL391817-1|CAI17033.1| 382|Homo sapiens proline/arginine-rich e... 66 2e-09
AK094891-1|BAC04451.1| 239|Homo sapiens protein ( Homo sapiens ... 66 2e-09
AK094131-1|BAC04294.1| 239|Homo sapiens (EC 2.4.1.101). protein. 66 2e-09
AK001637-1|BAA91801.1| 183|Homo sapiens protein ( Homo sapiens ... 66 2e-09
BC101077-1|AAI01078.1| 1041|Homo sapiens toll-like receptor 8 pr... 65 2e-09
BC101076-1|AAI01077.1| 1041|Homo sapiens toll-like receptor 8 pr... 65 2e-09
BC101075-1|AAI01076.1| 1041|Homo sapiens toll-like receptor 8 pr... 65 2e-09
BC101074-1|AAI01075.1| 1041|Homo sapiens toll-like receptor 8 pr... 65 2e-09
BC032667-1|AAH32667.1| 352|Homo sapiens keratocan protein. 65 2e-09
AY358296-1|AAQ88663.1| 1041|Homo sapiens TLR8 protein. 65 2e-09
AF246971-1|AAF64061.1| 1059|Homo sapiens Toll-like receptor 8 pr... 65 2e-09
AF245703-1|AAF78036.1| 1041|Homo sapiens toll-like receptor 8 pr... 65 2e-09
AF205403-1|AAF69126.1| 352|Homo sapiens keratocan protein. 65 2e-09
AF065988-1|AAC17741.1| 352|Homo sapiens keratocan protein. 65 2e-09
AF063301-1|AAC16390.1| 352|Homo sapiens keratan sulfate proteog... 65 2e-09
U93091-1|AAC80227.1| 839|Homo sapiens Toll protein homolog prot... 65 3e-09
U88880-1|AAC34135.1| 799|Homo sapiens Toll-like receptor 4 prot... 65 3e-09
BC117422-1|AAI17423.1| 839|Homo sapiens toll-like receptor 4 pr... 65 3e-09
AY358127-1|AAQ88494.1| 627|Homo sapiens AILP5865 protein. 65 3e-09
AL160272-2|CAH72619.1| 799|Homo sapiens toll-like receptor 4 pr... 65 3e-09
AL160272-1|CAH72618.1| 839|Homo sapiens toll-like receptor 4 pr... 65 3e-09
AF177765-1|AAF05316.1| 839|Homo sapiens toll-like receptor 4 pr... 65 3e-09
AF172171-1|AAF89753.1| 839|Homo sapiens toll-like receptor 4 pr... 65 3e-09
AL122074-1|CAB59249.1| 333|Homo sapiens hypothetical protein pr... 64 4e-09
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 64 4e-09
D63481-1|BAA09768.3| 1630|Homo sapiens KIAA0147 protein protein. 64 5e-09
BC046356-1|AAH46356.1| 421|Homo sapiens osteomodulin protein. 64 5e-09
AY358872-1|AAQ89231.1| 421|Homo sapiens OMD protein. 64 5e-09
AY062238-1|AAL38976.1| 1630|Homo sapiens scribble protein. 64 5e-09
AL137848-4|CAI16696.1| 421|Homo sapiens osteomodulin protein. 64 5e-09
AK021896-1|BAB13929.1| 197|Homo sapiens protein ( Homo sapiens ... 64 5e-09
AF271734-1|AAP88018.1| 1601|Homo sapiens SCRIB1 variant N1 protein. 64 5e-09
AF240677-1|AAP88017.1| 1630|Homo sapiens CRIB1 protein. 64 5e-09
AB009589-1|BAA23982.1| 421|Homo sapiens Osteomodulin protein. 64 5e-09
AB000114-1|BAA19055.1| 421|Homo sapiens osteomodulin protein. 64 5e-09
BC125270-1|AAI25271.1| 669|Homo sapiens FSHR protein protein. 63 9e-09
AK000338-1|BAA91094.1| 384|Homo sapiens protein ( Homo sapiens ... 63 9e-09
D86984-1|BAA13220.2| 823|Homo sapiens KIAA0231 protein protein. 63 1e-08
BC074741-1|AAH74741.1| 345|Homo sapiens leucine-rich repeats an... 63 1e-08
BC060782-1|AAH60782.1| 803|Homo sapiens LRRC8B protein protein. 63 1e-08
BC030607-1|AAH30607.1| 803|Homo sapiens leucine rich repeat con... 63 1e-08
AF385436-1|AAM43837.1| 803|Homo sapiens T-cell activation leuci... 63 1e-08
AF225421-1|AAG09723.1| 345|Homo sapiens HT017 protein. 63 1e-08
AB023148-1|BAA76775.2| 1258|Homo sapiens KIAA0931 protein protein. 63 1e-08
X57436-1|CAA40684.1| 440|Homo sapiens oligodentrocyte-myelin gl... 62 2e-08
X51694-1|CAA35991.1| 433|Homo sapiens oligodendrocyte-myelin gl... 62 2e-08
M63623-1|AAA59970.1| 440|Homo sapiens oligodendrocyte-myelin gl... 62 2e-08
BC018050-1|AAH18050.1| 440|Homo sapiens oligodendrocyte myelin ... 62 2e-08
AY358889-1|AAQ89248.1| 440|Homo sapiens p37NB protein. 62 2e-08
AK222663-1|BAD96383.1| 440|Homo sapiens oligodendrocyte myelin ... 62 2e-08
AK074723-1|BAC11161.1| 546|Homo sapiens protein ( Homo sapiens ... 62 2e-08
BC111013-1|AAI11014.1| 428|Homo sapiens immunoglobulin superfam... 62 2e-08
BC022478-1|AAH22478.1| 428|Homo sapiens immunoglobulin superfam... 62 2e-08
AY358871-1|AAQ89230.1| 428|Homo sapiens ISLR protein. 62 2e-08
AY324322-1|AAQ97217.1| 469|Homo sapiens leucine-rich repeat neu... 62 2e-08
AB024537-1|BAA85971.1| 428|Homo sapiens ISLR protein. 62 2e-08
AB024536-1|BAA85970.1| 428|Homo sapiens ISLR protein. 62 2e-08
AB003184-1|BAA22848.1| 428|Homo sapiens ISLR protein. 62 2e-08
BC132983-1|AAI32984.1| 313|Homo sapiens leucine rich repeat con... 62 3e-08
BC132981-1|AAI32982.1| 313|Homo sapiens leucine rich repeat con... 62 3e-08
BC126156-1|AAI26157.1| 370|Homo sapiens leucine rich repeat con... 62 3e-08
AL157714-2|CAI15338.1| 313|Homo sapiens novel protein protein. 62 3e-08
AK222987-1|BAD96707.1| 370|Homo sapiens leucine rich repeat con... 62 3e-08
AK098677-1|BAC05375.1| 313|Homo sapiens protein ( Homo sapiens ... 62 3e-08
AK024955-1|BAB15042.1| 370|Homo sapiens protein ( Homo sapiens ... 62 3e-08
AB040917-1|BAA96008.1| 700|Homo sapiens KIAA1484 protein protein. 62 3e-08
AY358116-1|AAQ88483.1| 548|Homo sapiens LGI3 protein. 61 4e-08
AK223267-1|BAD96987.1| 428|Homo sapiens immunoglobulin superfam... 61 4e-08
AJ487961-1|CAD32308.1| 548|Homo sapiens LGI1-like protein 4 pro... 61 4e-08
AJ487518-1|CAD31786.1| 548|Homo sapiens leucine-rich glioma ina... 61 4e-08
AF467956-1|AAM49554.1| 548|Homo sapiens LGI3 protein. 61 4e-08
M22403-1|AAA52596.1| 626|Homo sapiens platelet membrane glycopr... 61 5e-08
J02940-1|AAA52595.1| 626|Homo sapiens GP1BA protein. 61 5e-08
DQ355157-1|ABC79623.1| 334|Homo sapiens cytokeratin associated ... 61 5e-08
BC051322-1|AAH51322.1| 810|Homo sapiens leucine rich repeat con... 61 5e-08
BC029118-1|AAH29118.1| 371|Homo sapiens leucine rich repeat con... 61 5e-08
BC027955-1|AAH27955.1| 626|Homo sapiens glycoprotein Ib (platel... 61 5e-08
BC027903-1|AAH27903.1| 441|Homo sapiens leucine rich repeat con... 61 5e-08
AY358286-1|AAQ88653.1| 546|Homo sapiens RQTI221 protein. 61 5e-08
AY143166-1|AAN18279.1| 810|Homo sapiens leucine-rich repeat-con... 61 5e-08
AM709890-1|CAM97225.1| 639|Homo sapiens platelet glycoprotein I... 61 5e-08
AL929554-11|CAH72880.1| 334|Homo sapiens leucine rich repeat co... 61 5e-08
AL672142-1|CAI10839.1| 810|Homo sapiens leucine rich repeat con... 61 5e-08
AK223440-1|BAD97160.1| 371|Homo sapiens leucine rich repeat con... 61 5e-08
AK057808-1|BAB71585.1| 371|Homo sapiens protein ( Homo sapiens ... 61 5e-08
AK027495-1|BAB55153.1| 474|Homo sapiens protein ( Homo sapiens ... 61 5e-08
AF395009-1|AAK71325.1| 626|Homo sapiens glycoprotein Ib (platel... 61 5e-08
AB086948-1|BAC10305.1| 626|Homo sapiens platelet glycoprotein I... 61 5e-08
AB037858-1|BAA92675.1| 811|Homo sapiens KIAA1437 protein protein. 61 5e-08
BC044233-1|AAH44233.1| 692|Homo sapiens leucine rich repeat con... 60 6e-08
AY358322-1|AAQ88688.1| 692|Homo sapiens ELLP3030 protein. 60 6e-08
Z94160-2|CAI22122.1| 820|Homo sapiens protein ( Human DNA seque... 60 8e-08
BC113973-1|AAI13974.1| 803|Homo sapiens factor for adipocyte di... 60 8e-08
BC111067-1|AAI11068.1| 513|Homo sapiens leucine rich repeat con... 60 8e-08
AB178281-1|BAD97811.1| 513|Homo sapiens LRRC24 protein protein. 60 8e-08
AB081509-1|BAB86303.1| 803|Homo sapiens AD158 protein. 60 8e-08
AB067491-1|BAB67797.1| 821|Homo sapiens KIAA1904 protein protein. 60 8e-08
AB038516-1|BAB12038.1| 626|Homo sapiens platelet glycoprotein I... 60 8e-08
BC105958-1|AAI05959.1| 677|Homo sapiens ECM2 protein protein. 60 1e-07
BC009613-1|AAH09613.1| 335|Homo sapiens leucine rich repeat con... 60 1e-07
AY358131-1|AAQ88498.1| 335|Homo sapiens densin hlg protein. 60 1e-07
AL445928-6|CAH72254.1| 339|Homo sapiens leucine rich repeat con... 60 1e-07
AL445928-5|CAH72253.1| 335|Homo sapiens leucine rich repeat con... 60 1e-07
BC108252-1|AAI08253.1| 532|Homo sapiens LRRC8E protein protein. 59 1e-07
BC095477-1|AAH95477.1| 522|Homo sapiens AMIGO2 protein protein. 59 1e-07
BC070089-1|AAH70089.1| 796|Homo sapiens leucine rich repeat con... 59 1e-07
BC047595-1|AAH47595.1| 522|Homo sapiens adhesion molecule with ... 59 1e-07
BC024159-1|AAH24159.2| 858|Homo sapiens leucine rich repeat con... 59 1e-07
BC022500-1|AAH22500.1| 557|Homo sapiens leucine-rich, glioma in... 59 1e-07
BC022216-1|AAH22216.2| 592|Homo sapiens LRRC8E protein protein. 59 1e-07
AY454159-1|AAR83271.1| 522|Homo sapiens DEGA/AMIGO-2 precursor ... 59 1e-07
AY358885-1|AAQ89244.1| 557|Homo sapiens LGI1 protein. 59 1e-07
AY358874-1|AAQ89233.1| 501|Homo sapiens LRRC5 protein. 59 1e-07
AY237005-1|AAO48946.1| 522|Homo sapiens transmembrane protein A... 59 1e-07
AL834474-1|CAD39133.1| 622|Homo sapiens hypothetical protein pr... 59 1e-07
AL391497-3|CAH72226.1| 858|Homo sapiens leucine rich repeat con... 59 1e-07
AL358154-2|CAI14982.1| 557|Homo sapiens leucine-rich, glioma in... 59 1e-07
AL358154-1|CAI14981.1| 291|Homo sapiens leucine-rich, glioma in... 59 1e-07
AL157396-3|CAH73838.1| 557|Homo sapiens leucine-rich, glioma in... 59 1e-07
AL157396-2|CAH73837.1| 291|Homo sapiens leucine-rich, glioma in... 59 1e-07
AL137848-6|CAI16698.1| 243|Homo sapiens asporin (LRR class 1) p... 59 1e-07
AK027359-1|BAB55060.1| 246|Homo sapiens protein ( Homo sapiens ... 59 1e-07
AK027073-1|BAB15648.1| 444|Homo sapiens protein ( Homo sapiens ... 59 1e-07
AK001332-1|BAA91631.1| 682|Homo sapiens protein ( Homo sapiens ... 59 1e-07
AF473548-1|AAM22074.1| 291|Homo sapiens leucine-rich glioma ina... 59 1e-07
AF055636-1|AAC99316.1| 557|Homo sapiens leucine-rich glioma-ina... 59 1e-07
AB080610-1|BAC81189.1| 522|Homo sapiens alivin 1 protein. 59 1e-07
BC101761-1|AAI01762.1| 545|Homo sapiens leucine-rich repeat LGI... 59 2e-07
BC101759-1|AAI01760.1| 545|Homo sapiens leucine-rich repeat LGI... 59 2e-07
AJ487958-1|CAD32305.1| 545|Homo sapiens LGI1-like protein 2 pro... 59 2e-07
AJ487516-1|CAD31784.1| 545|Homo sapiens leucine-rich glioma ina... 59 2e-07
AF467955-1|AAM49553.1| 545|Homo sapiens LGI2 protein. 59 2e-07
AF177766-1|AAF07823.1| 752|Homo sapiens human toll-like recepto... 59 2e-07
AB067503-1|BAB67809.1| 542|Homo sapiens KIAA1916 protein protein. 59 2e-07
BX537976-1|CAD97940.1| 693|Homo sapiens hypothetical protein pr... 58 3e-07
BC107493-1|AAI07494.1| 699|Homo sapiens extracellular matrix pr... 58 3e-07
AL157827-4|CAI12589.1| 699|Homo sapiens extracellular matrix pr... 58 3e-07
AL137848-1|CAI16693.1| 699|Homo sapiens extracellular matrix pr... 58 3e-07
>J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precursor
protein.
Length = 545
Score = 149 bits (361), Expect = 1e-34
Identities = 99/332 (29%), Positives = 139/332 (41%), Gaps = 1/332 (0%)
Query: 9 LPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFL 68
L IF +L +L L L N LE + F L + L N L LP +LF T L
Sbjct: 112 LSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHL 171
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINN 127
+T++++ N + +P + F L SLQ L LS N + + G F L +LQ L L N I+
Sbjct: 172 KTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISE 231
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ F RN + ++P +F +L L FL L N L L F L
Sbjct: 232 LPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCL 291
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
L L N L + + TF+ NL L LS N + + F
Sbjct: 292 VGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTA 351
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVR 307
+H F L L L L N +LP D L + L GNPW CDCH Y+ W++
Sbjct: 352 LHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGNPWQCDCHLAYLFNWLQ 411
Query: 308 LNEMKIWDYSPTCVSPWYLEGHFLKKLKFPEL 339
++ + C P YL+G + L +L
Sbjct: 412 QYTDRLLNIQTYCAGPAYLKGQVVPALNEKQL 443
Score = 85.4 bits (202), Expect = 2e-15
Identities = 70/279 (25%), Positives = 114/279 (40%), Gaps = 1/279 (0%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F S NL + L + +AF +L ++++ + L +F+N T L + +
Sbjct: 69 FGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTL 128
Query: 74 SNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNA 132
+ N + +P F L +L+ L L N++Q + F L +L+ L L+ N + + +
Sbjct: 129 NFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEEL 188
Query: 133 FENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDL 192
F N L +P +F L L L L +NN+ L F L L L L
Sbjct: 189 FHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWL 248
Query: 193 KENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKA 252
+ NA++ +P + F+ NL L L N LR + F V
Sbjct: 249 QRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGT 308
Query: 253 FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
F+ L NL +L L N LP+ + +L + L N
Sbjct: 309 FAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSN 347
Score = 47.6 bits (108), Expect = 5e-04
Identities = 31/100 (31%), Positives = 49/100 (49%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N +E + G F L NL++L L N + + + F ++L + L +N L L LF
Sbjct: 299 NQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQ 358
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQ 103
N + LE + +S N++ +P F Y+L L L N Q
Sbjct: 359 NLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGNPWQ 398
>BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 149 bits (361), Expect = 1e-34
Identities = 99/332 (29%), Positives = 139/332 (41%), Gaps = 1/332 (0%)
Query: 9 LPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFL 68
L IF +L +L L L N LE + F L + L N L LP +LF T L
Sbjct: 112 LSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHL 171
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINN 127
+T++++ N + +P + F L SLQ L LS N + + G F L +LQ L L N I+
Sbjct: 172 KTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISE 231
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ F RN + ++P +F +L L FL L N L L F L
Sbjct: 232 LPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCL 291
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
L L N L + + TF+ NL L LS N + + F
Sbjct: 292 VGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTA 351
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVR 307
+H F L L L L N +LP D L + L GNPW CDCH Y+ W++
Sbjct: 352 LHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGNPWQCDCHLAYLFNWLQ 411
Query: 308 LNEMKIWDYSPTCVSPWYLEGHFLKKLKFPEL 339
++ + C P YL+G + L +L
Sbjct: 412 QYTDRLLNIQTYCAGPAYLKGQVVPALNEKQL 443
Score = 85.4 bits (202), Expect = 2e-15
Identities = 70/279 (25%), Positives = 114/279 (40%), Gaps = 1/279 (0%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F S NL + L + +AF +L ++++ + L +F+N T L + +
Sbjct: 69 FGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTL 128
Query: 74 SNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNA 132
+ N + +P F L +L+ L L N++Q + F L +L+ L L+ N + + +
Sbjct: 129 NFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEEL 188
Query: 133 FENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDL 192
F N L +P +F L L L L +NN+ L F L L L L
Sbjct: 189 FHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWL 248
Query: 193 KENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKA 252
+ NA++ +P + F+ NL L L N LR + F V
Sbjct: 249 QRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGT 308
Query: 253 FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
F+ L NL +L L N LP+ + +L + L N
Sbjct: 309 FAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSN 347
Score = 47.6 bits (108), Expect = 5e-04
Identities = 31/100 (31%), Positives = 49/100 (49%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N +E + G F L NL++L L N + + + F ++L + L +N L L LF
Sbjct: 299 NQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQ 358
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQ 103
N + LE + +S N++ +P F Y+L L L N Q
Sbjct: 359 NLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGNPWQ 398
>BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 149 bits (360), Expect = 1e-34
Identities = 99/332 (29%), Positives = 139/332 (41%), Gaps = 1/332 (0%)
Query: 9 LPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFL 68
L IF +L +L L L N LE + F L + L N L LP +LF T L
Sbjct: 112 LSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNRLQALPRRLFQPLTHL 171
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINN 127
+T++++ N + +P + F L SLQ L LS N + + G F L +LQ L L N I+
Sbjct: 172 KTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISE 231
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ F RN + ++P +F +L L FL L N L L F L
Sbjct: 232 LPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCL 291
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
L L N L + + TF+ NL L LS N + + F
Sbjct: 292 VGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTA 351
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVR 307
+H F L L L L N +LP D L + L GNPW CDCH Y+ W++
Sbjct: 352 LHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGNPWQCDCHLAYLFNWLQ 411
Query: 308 LNEMKIWDYSPTCVSPWYLEGHFLKKLKFPEL 339
++ + C P YL+G + L +L
Sbjct: 412 QYTDRLLNIQTYCAGPAYLKGQVVPALNEKQL 443
Score = 85.8 bits (203), Expect = 1e-15
Identities = 70/279 (25%), Positives = 114/279 (40%), Gaps = 1/279 (0%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F S NL + L + +AF +L ++++ + L +F+N T L + +
Sbjct: 69 FGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTL 128
Query: 74 SNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNA 132
+ N + +P F L +L+ L L N++Q + F L +L+ L L+ N + + +
Sbjct: 129 NFNMLEALPEGLFQHLAALESLHLQGNRLQALPRRLFQPLTHLKTLNLAQNLLAQLPEEL 188
Query: 133 FENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDL 192
F N L +P +F L L L L +NN+ L F L L L L
Sbjct: 189 FHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWL 248
Query: 193 KENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKA 252
+ NA++ +P + F+ NL L L N LR + F V
Sbjct: 249 QRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGT 308
Query: 253 FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
F+ L NL +L L N LP+ + +L + L N
Sbjct: 309 FAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSN 347
Score = 47.6 bits (108), Expect = 5e-04
Identities = 31/100 (31%), Positives = 49/100 (49%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N +E + G F L NL++L L N + + + F ++L + L +N L L LF
Sbjct: 299 NQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQ 358
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQ 103
N + LE + +S N++ +P F Y+L L L N Q
Sbjct: 359 NLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGNPWQ 398
>BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein.
Length = 581
Score = 148 bits (358), Expect = 2e-34
Identities = 106/355 (29%), Positives = 165/355 (46%), Gaps = 26/355 (7%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ LP G+F+ L +L++L L N L +I F+ L + L N+L +P+ F
Sbjct: 110 NNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAF 169
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
+ L +++ N + ++ F L +LQ+L L +N++ +I GTF L NLQ L L
Sbjct: 170 DHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQ 229
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N+I +S F N N + +P +F L L L L N+L L+ F
Sbjct: 230 QNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGIF 289
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXX 241
+ LR L L +N +S +PDN FS+ L+ L LS+N++ FI+ AF G
Sbjct: 290 GPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLH 349
Query: 242 XXXXYEVHFKAFSMLKNLTTL--------YLDGNMF----------------PSLPSRTL 277
++ F ML NL + L GN+F +LP
Sbjct: 350 TNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIF 409
Query: 278 DYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKI-WDYSPTCVSPWYLEGHFL 331
D++ KL ++L NPW CD L + W+ LN+ ++ D P C SP + G L
Sbjct: 410 DHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVPVCFSPANVRGQSL 464
Score = 101 bits (243), Expect = 2e-20
Identities = 73/274 (26%), Positives = 123/274 (44%), Gaps = 1/274 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N +L++ ++ E++ F + L + + N L + F N L + ++NN++
Sbjct: 54 NAMSLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKL 113
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXX 137
+P F GL SL+ L LS N++ IQ FS NL+ L+L N + I D AF++
Sbjct: 114 QVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLV 173
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
+N L +I ++F +L L L L N L + F+ L L+ L L++N +
Sbjct: 174 GLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQI 233
Query: 198 SQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLK 257
+ F + NL++L LS N + + + F E+ F +
Sbjct: 234 GLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGIFGPMP 293
Query: 258 NLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
NL L+L N SLP + +L ++ LS N
Sbjct: 294 NLRELWLYDNHISSLPDNVFSNLRQLQVLILSRN 327
Score = 94.7 bits (225), Expect = 3e-18
Identities = 66/223 (29%), Positives = 106/223 (47%), Gaps = 1/223 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+++N + +P G F+ LVNL+ L LQ+N + + F + L + LSNN++ LP
Sbjct: 204 LYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPS 263
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
+F L + + N + + F + +L+ L L N I ++ + FS L+ LQ+L
Sbjct: 264 VFMQLPQLNRLTLFGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLI 323
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
LS N+I+ IS AF N L+++ +F L L + L NN L L G
Sbjct: 324 LSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGN 383
Query: 180 EFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
F ++ L + L+ N L +P F L +L L N R
Sbjct: 384 IFANVNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLYDNPWR 426
Score = 93.1 bits (221), Expect = 1e-17
Identities = 76/292 (26%), Positives = 126/292 (43%), Gaps = 1/292 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ + H+ L F ++ L LR+++N L I AF + L ++ L+NN L LP
Sbjct: 60 ILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIG 119
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
LF LE++ +S+N+++ + F +L+ L L N ++ I +G F L L L
Sbjct: 120 LFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLN 179
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
L N + +IS F++ N+L +IP F+ L L L L N + L+
Sbjct: 180 LGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPG 239
Query: 180 EFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXX 239
F + L+ L L N +SQ+P + F L +L L N L+ ++ F
Sbjct: 240 LFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGIFGPMPNLRELW 299
Query: 240 XXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ FS L+ L L L N + + + +L + L N
Sbjct: 300 LYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTN 351
Score = 77.4 bits (182), Expect = 5e-13
Identities = 60/221 (27%), Positives = 89/221 (40%), Gaps = 2/221 (0%)
Query: 71 IDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISD 130
++ + R+V VP+ SLQIL+ ++ ++ ++ L L++ N+++ I+
Sbjct: 37 VECTGARIVAVPTPLPWNAMSLQILNTHITELN--ESPFLNISALIALRIEKNELSRITP 94
Query: 131 NAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNL 190
AF N NKL+ +P LF L L L LS+N L+ + F L+ L
Sbjct: 95 GAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKEL 154
Query: 191 DLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHF 250
L N L IPD F L KL+L KN L I+ F ++
Sbjct: 155 QLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPM 214
Query: 251 KAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
F L NL L L N L L + LS N
Sbjct: 215 GTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNN 255
>BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat
containing 15 protein.
Length = 581
Score = 148 bits (358), Expect = 2e-34
Identities = 106/355 (29%), Positives = 165/355 (46%), Gaps = 26/355 (7%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ LP G+F+ L +L++L L N L +I F+ L + L N+L +P+ F
Sbjct: 110 NNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAF 169
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
+ L +++ N + ++ F L +LQ+L L +N++ +I GTF L NLQ L L
Sbjct: 170 DHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQ 229
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N+I +S F N N + +P +F L L L L N+L L+ F
Sbjct: 230 QNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGIF 289
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXX 241
+ LR L L +N +S +PDN FS+ L+ L LS+N++ FI+ AF G
Sbjct: 290 GPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLH 349
Query: 242 XXXXYEVHFKAFSMLKNLTTL--------YLDGNMF----------------PSLPSRTL 277
++ F ML NL + L GN+F +LP
Sbjct: 350 TNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIF 409
Query: 278 DYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKI-WDYSPTCVSPWYLEGHFL 331
D++ KL ++L NPW CD L + W+ LN+ ++ D P C SP + G L
Sbjct: 410 DHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVPVCFSPANVRGQSL 464
Score = 101 bits (243), Expect = 2e-20
Identities = 73/274 (26%), Positives = 123/274 (44%), Gaps = 1/274 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N +L++ ++ E++ F + L + + N L + F N L + ++NN++
Sbjct: 54 NAMSLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKL 113
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXX 137
+P F GL SL+ L LS N++ IQ FS NL+ L+L N + I D AF++
Sbjct: 114 QVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLV 173
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
+N L +I ++F +L L L L N L + F+ L L+ L L++N +
Sbjct: 174 GLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQI 233
Query: 198 SQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLK 257
+ F + NL++L LS N + + + F E+ F +
Sbjct: 234 GLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGIFGPMP 293
Query: 258 NLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
NL L+L N SLP + +L ++ LS N
Sbjct: 294 NLRELWLYDNHISSLPDNVFSNLRQLQVLILSRN 327
Score = 94.7 bits (225), Expect = 3e-18
Identities = 66/223 (29%), Positives = 106/223 (47%), Gaps = 1/223 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+++N + +P G F+ LVNL+ L LQ+N + + F + L + LSNN++ LP
Sbjct: 204 LYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPS 263
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
+F L + + N + + F + +L+ L L N I ++ + FS L+ LQ+L
Sbjct: 264 VFMQLPQLNRLTLFGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLI 323
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
LS N+I+ IS AF N L+++ +F L L + L NN L L G
Sbjct: 324 LSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGN 383
Query: 180 EFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
F ++ L + L+ N L +P F L +L L N R
Sbjct: 384 IFANVNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLYDNPWR 426
Score = 93.1 bits (221), Expect = 1e-17
Identities = 76/292 (26%), Positives = 126/292 (43%), Gaps = 1/292 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ + H+ L F ++ L LR+++N L I AF + L ++ L+NN L LP
Sbjct: 60 ILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIG 119
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
LF LE++ +S+N+++ + F +L+ L L N ++ I +G F L L L
Sbjct: 120 LFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLN 179
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
L N + +IS F++ N+L +IP F+ L L L L N + L+
Sbjct: 180 LGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPG 239
Query: 180 EFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXX 239
F + L+ L L N +SQ+P + F L +L L N L+ ++ F
Sbjct: 240 LFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGIFGPMPNLRELW 299
Query: 240 XXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ FS L+ L L L N + + + +L + L N
Sbjct: 300 LYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTN 351
Score = 77.4 bits (182), Expect = 5e-13
Identities = 60/221 (27%), Positives = 89/221 (40%), Gaps = 2/221 (0%)
Query: 71 IDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISD 130
++ + R+V VP+ SLQIL+ ++ ++ ++ L L++ N+++ I+
Sbjct: 37 VECTGARIVAVPTPLPWNAMSLQILNTHITELN--ESPFLNISALIALRIEKNELSRITP 94
Query: 131 NAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNL 190
AF N NKL+ +P LF L L L LS+N L+ + F L+ L
Sbjct: 95 GAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKEL 154
Query: 191 DLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHF 250
L N L IPD F L KL+L KN L I+ F ++
Sbjct: 155 QLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPM 214
Query: 251 KAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
F L NL L L N L L + LS N
Sbjct: 215 GTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNN 255
>AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein.
Length = 581
Score = 147 bits (357), Expect = 3e-34
Identities = 106/355 (29%), Positives = 165/355 (46%), Gaps = 26/355 (7%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ LP G+F+ L +L++L L N L +I F+ L + L N+L +P+ F
Sbjct: 110 NNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAF 169
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
+ L +++ N + ++ F L +LQ+L L +N++ +I GTF L NLQ L L
Sbjct: 170 DHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQ 229
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N+I +S F N N + +P +F L L L L N+L L+ F
Sbjct: 230 QNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIF 289
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXX 241
+ LR L L +N +S +PDN FS+ L+ L LS+N++ FI+ AF G
Sbjct: 290 GPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLH 349
Query: 242 XXXXYEVHFKAFSMLKNLTTL--------YLDGNMF----------------PSLPSRTL 277
++ F ML NL + L GN+F +LP
Sbjct: 350 TNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIF 409
Query: 278 DYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKI-WDYSPTCVSPWYLEGHFL 331
D++ KL ++L NPW CD L + W+ LN+ ++ D P C SP + G L
Sbjct: 410 DHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVPVCFSPANVRGQSL 464
Score = 103 bits (246), Expect = 9e-21
Identities = 73/274 (26%), Positives = 123/274 (44%), Gaps = 1/274 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N +L++ ++ E++ F + L + + N L + F N L + ++NN++
Sbjct: 54 NAMSLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKL 113
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXX 137
+P F GL SL+ L LS N++ IQ FS NL+ L+L N + I D AF++
Sbjct: 114 QVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLV 173
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
+N L +I ++F +L L L L N L + F+ L L+ L L++N +
Sbjct: 174 GLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQI 233
Query: 198 SQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLK 257
+ F + NL++L LS N + + + F E+ F +
Sbjct: 234 GLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMP 293
Query: 258 NLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
NL L+L N SLP + +L ++ LS N
Sbjct: 294 NLRELWLYDNHISSLPDNVFSNLRQLQVLILSRN 327
Score = 94.7 bits (225), Expect = 3e-18
Identities = 76/292 (26%), Positives = 127/292 (43%), Gaps = 1/292 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ + H+ L F ++ L LR+++N L I AF + L ++ L+NN L LP
Sbjct: 60 ILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIG 119
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
LF LE++ +S+N+++ + F +L+ L L N ++ I +G F L L L
Sbjct: 120 LFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLN 179
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
L N + +IS F++ N+L +IP F+ L L L L N + L+
Sbjct: 180 LGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPG 239
Query: 180 EFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXX 239
F + L+ L L N +SQ+P + F L +L L N L+ +++ F
Sbjct: 240 LFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELW 299
Query: 240 XXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ FS L+ L L L N + + + +L + L N
Sbjct: 300 LYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTN 351
Score = 94.7 bits (225), Expect = 3e-18
Identities = 66/223 (29%), Positives = 106/223 (47%), Gaps = 1/223 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+++N + +P G F+ LVNL+ L LQ+N + + F + L + LSNN++ LP
Sbjct: 204 LYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPS 263
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
+F L + + N + + F + +L+ L L N I ++ + FS L+ LQ+L
Sbjct: 264 IFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLI 323
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
LS N+I+ IS AF N L+++ +F L L + L NN L L G
Sbjct: 324 LSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGN 383
Query: 180 EFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
F ++ L + L+ N L +P F L +L L N R
Sbjct: 384 IFANVNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLYDNPWR 426
Score = 77.4 bits (182), Expect = 5e-13
Identities = 60/221 (27%), Positives = 89/221 (40%), Gaps = 2/221 (0%)
Query: 71 IDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISD 130
++ + R+V VP+ SLQIL+ ++ ++ ++ L L++ N+++ I+
Sbjct: 37 VECTGARIVAVPTPLPWNAMSLQILNTHITELN--ESPFLNISALIALRIEKNELSRITP 94
Query: 131 NAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNL 190
AF N NKL+ +P LF L L L LS+N L+ + F L+ L
Sbjct: 95 GAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKEL 154
Query: 191 DLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHF 250
L N L IPD F L KL+L KN L I+ F ++
Sbjct: 155 QLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPM 214
Query: 251 KAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
F L NL L L N L L + LS N
Sbjct: 215 GTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNN 255
>BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat
transmembrane neuronal 2 protein.
Length = 516
Score = 134 bits (324), Expect = 3e-30
Identities = 90/283 (31%), Positives = 137/283 (48%), Gaps = 2/283 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L +N++ L FA+ + L + + +N++ V D+F GLY L+ L LS NKI +
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
N TF+ L NLQ L LS N+++++ F N L+ IP +LF + + L F
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
LDLS N L SLA F L LR L L+ N L++I F +L L L NK+ +
Sbjct: 186 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 245
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
+ + F + NL L +D N SL S+ L+ + LT
Sbjct: 246 CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTT 305
Query: 286 VKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG 328
V LSGN W C +++W+ + + W++S C SP + +G
Sbjct: 306 VGLSGNLWECSARICALASWLGSFQGR-WEHSILCHSPDHTQG 347
Score = 89.4 bits (212), Expect = 1e-16
Identities = 62/193 (32%), Positives = 91/193 (47%), Gaps = 1/193 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + YLP F L+NL+ L L N L + E F +KL + L +N L T+P +LF
Sbjct: 119 NKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFW 178
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ LE +D+S NR+ + + F GL L+ L L N++ I F L +L L L
Sbjct: 179 DCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQW 238
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
NKI+N++ N++K I +F + L L + NN L SL
Sbjct: 239 NKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILN 298
Query: 183 SLKLLRNLDLKEN 195
SL+ L + L N
Sbjct: 299 SLRSLTTVGLSGN 311
Score = 88.2 bits (209), Expect = 3e-16
Identities = 65/224 (29%), Positives = 102/224 (45%), Gaps = 3/224 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ L F S L L L N + + +AF KL + LS+N ++ LP F
Sbjct: 71 NHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFT 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L+ +D+S N++ + + F GL LQ L L N ++ I F ++L+ L LS
Sbjct: 131 QLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLST 190
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSL-AGVEF 181
N++ +++ N F + N+L I F L L L L N + +L G+E+
Sbjct: 191 NRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEW 250
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
+ L LDL N + I F NL+ L + NKL ++
Sbjct: 251 -TWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLD 293
>BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat
transmembrane neuronal 2 protein.
Length = 516
Score = 134 bits (324), Expect = 3e-30
Identities = 90/283 (31%), Positives = 137/283 (48%), Gaps = 2/283 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L +N++ L FA+ + L + + +N++ V D+F GLY L+ L LS NKI +
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
N TF+ L NLQ L LS N+++++ F N L+ IP +LF + + L F
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
LDLS N L SLA F L LR L L+ N L++I F +L L L NK+ +
Sbjct: 186 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 245
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
+ + F + NL L +D N SL S+ L+ + LT
Sbjct: 246 CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTT 305
Query: 286 VKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG 328
V LSGN W C +++W+ + + W++S C SP + +G
Sbjct: 306 VGLSGNLWECSARICALASWLGSFQGR-WEHSILCHSPDHTQG 347
Score = 89.4 bits (212), Expect = 1e-16
Identities = 62/193 (32%), Positives = 91/193 (47%), Gaps = 1/193 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + YLP F L+NL+ L L N L + E F +KL + L +N L T+P +LF
Sbjct: 119 NKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFW 178
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ LE +D+S NR+ + + F GL L+ L L N++ I F L +L L L
Sbjct: 179 DCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQW 238
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
NKI+N++ N++K I +F + L L + NN L SL
Sbjct: 239 NKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILN 298
Query: 183 SLKLLRNLDLKEN 195
SL+ L + L N
Sbjct: 299 SLRSLTTVGLSGN 311
Score = 88.2 bits (209), Expect = 3e-16
Identities = 65/224 (29%), Positives = 102/224 (45%), Gaps = 3/224 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ L F S L L L N + + +AF KL + LS+N ++ LP F
Sbjct: 71 NHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFT 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L+ +D+S N++ + + F GL LQ L L N ++ I F ++L+ L LS
Sbjct: 131 QLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLST 190
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSL-AGVEF 181
N++ +++ N F + N+L I F L L L L N + +L G+E+
Sbjct: 191 NRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEW 250
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
+ L LDL N + I F NL+ L + NKL ++
Sbjct: 251 -TWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLD 293
>AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat
transmembrane neuronal 2 protein protein.
Length = 516
Score = 134 bits (324), Expect = 3e-30
Identities = 90/283 (31%), Positives = 137/283 (48%), Gaps = 2/283 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L +N++ L FA+ + L + + +N++ V D+F GLY L+ L LS NKI +
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
N TF+ L NLQ L LS N+++++ F N L+ IP +LF + + L F
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
LDLS N L SLA F L LR L L+ N L++I F +L L L NK+ +
Sbjct: 186 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 245
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
+ + F + NL L +D N SL S+ L+ + LT
Sbjct: 246 CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTT 305
Query: 286 VKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG 328
V LSGN W C +++W+ + + W++S C SP + +G
Sbjct: 306 VGLSGNLWECSARICALASWLGSFQGR-WEHSILCHSPDHTQG 347
Score = 89.4 bits (212), Expect = 1e-16
Identities = 62/193 (32%), Positives = 91/193 (47%), Gaps = 1/193 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + YLP F L+NL+ L L N L + E F +KL + L +N L T+P +LF
Sbjct: 119 NKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFW 178
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ LE +D+S NR+ + + F GL L+ L L N++ I F L +L L L
Sbjct: 179 DCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQW 238
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
NKI+N++ N++K I +F + L L + NN L SL
Sbjct: 239 NKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILN 298
Query: 183 SLKLLRNLDLKEN 195
SL+ L + L N
Sbjct: 299 SLRSLTTVGLSGN 311
Score = 88.2 bits (209), Expect = 3e-16
Identities = 65/224 (29%), Positives = 102/224 (45%), Gaps = 3/224 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ L F S L L L N + + +AF KL + LS+N ++ LP F
Sbjct: 71 NHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFT 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L+ +D+S N++ + + F GL LQ L L N ++ I F ++L+ L LS
Sbjct: 131 QLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLST 190
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSL-AGVEF 181
N++ +++ N F + N+L I F L L L L N + +L G+E+
Sbjct: 191 NRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEW 250
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
+ L LDL N + I F NL+ L + NKL ++
Sbjct: 251 -TWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLD 293
>AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein.
Length = 529
Score = 134 bits (324), Expect = 3e-30
Identities = 90/283 (31%), Positives = 137/283 (48%), Gaps = 2/283 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L +N++ L FA+ + L + + +N++ V D+F GLY L+ L LS NKI +
Sbjct: 79 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 138
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
N TF+ L NLQ L LS N+++++ F N L+ IP +LF + + L F
Sbjct: 139 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 198
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
LDLS N L SLA F L LR L L+ N L++I F +L L L NK+ +
Sbjct: 199 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 258
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
+ + F + NL L +D N SL S+ L+ + LT
Sbjct: 259 CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTT 318
Query: 286 VKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG 328
V LSGN W C +++W+ + + W++S C SP + +G
Sbjct: 319 VGLSGNLWECSARICALASWLGSFQGR-WEHSILCHSPDHTQG 360
Score = 89.4 bits (212), Expect = 1e-16
Identities = 62/193 (32%), Positives = 91/193 (47%), Gaps = 1/193 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + YLP F L+NL+ L L N L + E F +KL + L +N L T+P +LF
Sbjct: 132 NKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFW 191
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ LE +D+S NR+ + + F GL L+ L L N++ I F L +L L L
Sbjct: 192 DCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQW 251
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
NKI+N++ N++K I +F + L L + NN L SL
Sbjct: 252 NKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILN 311
Query: 183 SLKLLRNLDLKEN 195
SL+ L + L N
Sbjct: 312 SLRSLTTVGLSGN 324
Score = 88.2 bits (209), Expect = 3e-16
Identities = 65/224 (29%), Positives = 102/224 (45%), Gaps = 3/224 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ L F S L L L N + + +AF KL + LS+N ++ LP F
Sbjct: 84 NHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFT 143
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L+ +D+S N++ + + F GL LQ L L N ++ I F ++L+ L LS
Sbjct: 144 QLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLST 203
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSL-AGVEF 181
N++ +++ N F + N+L I F L L L L N + +L G+E+
Sbjct: 204 NRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEW 263
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
+ L LDL N + I F NL+ L + NKL ++
Sbjct: 264 -TWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLD 306
>AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein.
Length = 622
Score = 123 bits (296), Expect = 8e-27
Identities = 89/331 (26%), Positives = 152/331 (45%), Gaps = 5/331 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ Y+ L +L L L + + + +AF + L+ + L+NN++ L +F
Sbjct: 70 NNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFK 129
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L + + N+V +VP F L S+Q L+L +N++ + +GTF + L+IL LS+
Sbjct: 130 GLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSN 189
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N I IS++ F++ N L +P+ F LK L L LS+N + ++ F+
Sbjct: 190 NNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFK 249
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L L L LK + + + + FS NL+ L LS N L +N F
Sbjct: 250 GLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDR 309
Query: 243 XXXYEVHFKAF-SMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALY 301
+ F +M +L L L N +L R L + L ++ + NPW C+C L
Sbjct: 310 NRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSNPWECNCKLLG 369
Query: 302 ISAWVRLNEMKIWDYSPTCVSPWYLEGHFLK 332
+ W+ + + + Y C +P + G L+
Sbjct: 370 LRDWLASSAITLNIY---CQNPPSMRGRALR 397
Score = 97.5 bits (232), Expect = 5e-19
Identities = 79/272 (29%), Positives = 115/272 (42%), Gaps = 4/272 (1%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSN-NYLYTLPEKLFANNTFLETIDISNNRVVYV 81
L L N + I+ T L + L N N LY P K F L + ++NN + +
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYP-KAFVQLRHLYFLFLNNNFIKRL 123
Query: 82 PSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXX 140
F GL +L+ L L N++ + G F+ L ++Q L L N++ + F
Sbjct: 124 DPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALR 183
Query: 141 XXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQI 200
N + I F +L+ L L L +NNL + FE LK LR L L N + I
Sbjct: 184 ILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAI 243
Query: 201 PDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLT 260
F NLE L L +++R + F G ++ FS+LKNL
Sbjct: 244 QPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLI 303
Query: 261 TLYLDGNMFPSLPSRTLDYM-PKLTIVKLSGN 291
L LD N S+ + T + M L I+ LS N
Sbjct: 304 YLKLDRNRIISIDNDTFENMGASLKILNLSFN 335
Score = 97.5 bits (232), Expect = 5e-19
Identities = 66/221 (29%), Positives = 107/221 (48%), Gaps = 2/221 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ L GIF+ L+NL+ L LQ N + + F + +++L N L L F
Sbjct: 117 NNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTF 176
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
L +D+SNN ++ + F L +L L L N + + + F LK+L+ L LS
Sbjct: 177 VGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLS 236
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N I I AF+ ++++N+ F+ + L L LS+N+L +L F
Sbjct: 237 HNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTF 296
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDC-FNLEKLDLSKNKL 221
LK L L L N + I ++TF + +L+ L+LS N L
Sbjct: 297 SLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNL 337
Score = 79.4 bits (187), Expect = 1e-13
Identities = 55/171 (32%), Positives = 86/171 (50%), Gaps = 2/171 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N++ + F+ L NL L L N L ++ S AF K L + LS+N + + F
Sbjct: 189 NNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAF 248
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
LE + + N+R+ V D F G+ +L+ L LS N ++N+ + TFS LKNL LKL
Sbjct: 249 KGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLD 308
Query: 122 DNKINNISDNAFEN-XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNN 171
N+I +I ++ FEN N L + ++ L LI L ++N
Sbjct: 309 RNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSN 359
Score = 76.6 bits (180), Expect = 9e-13
Identities = 48/175 (27%), Positives = 78/175 (44%)
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
L L+ N I+ I+++ D + + + + F L+ L FL L+NN + L
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLD 124
Query: 178 GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXX 237
F+ L LRNL L+ N +S +P F+D +++ L+L +N+L + F G
Sbjct: 125 PGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRI 184
Query: 238 XXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNP 292
+ F L+NL LYL N +PS + + L + LS NP
Sbjct: 185 LDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNP 239
>AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein.
Length = 622
Score = 123 bits (296), Expect = 8e-27
Identities = 89/331 (26%), Positives = 152/331 (45%), Gaps = 5/331 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ Y+ L +L L L + + + +AF + L+ + L+NN++ L +F
Sbjct: 70 NNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFK 129
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L + + N+V +VP F L S+Q L+L +N++ + +GTF + L+IL LS+
Sbjct: 130 GLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSN 189
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N I IS++ F++ N L +P+ F LK L L LS+N + ++ F+
Sbjct: 190 NNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFK 249
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L L L LK + + + + FS NL+ L LS N L +N F
Sbjct: 250 GLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDR 309
Query: 243 XXXYEVHFKAF-SMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALY 301
+ F +M +L L L N +L R L + L ++ + NPW C+C L
Sbjct: 310 NRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSNPWECNCKLLG 369
Query: 302 ISAWVRLNEMKIWDYSPTCVSPWYLEGHFLK 332
+ W+ + + + Y C +P + G L+
Sbjct: 370 LRDWLASSAITLNIY---CQNPPSMRGRALR 397
Score = 97.5 bits (232), Expect = 5e-19
Identities = 79/272 (29%), Positives = 115/272 (42%), Gaps = 4/272 (1%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSN-NYLYTLPEKLFANNTFLETIDISNNRVVYV 81
L L N + I+ T L + L N N LY P K F L + ++NN + +
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYP-KAFVQLRHLYFLFLNNNFIKRL 123
Query: 82 PSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXX 140
F GL +L+ L L N++ + G F+ L ++Q L L N++ + F
Sbjct: 124 DPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALR 183
Query: 141 XXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQI 200
N + I F +L+ L L L +NNL + FE LK LR L L N + I
Sbjct: 184 ILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAI 243
Query: 201 PDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLT 260
F NLE L L +++R + F G ++ FS+LKNL
Sbjct: 244 QPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLI 303
Query: 261 TLYLDGNMFPSLPSRTLDYM-PKLTIVKLSGN 291
L LD N S+ + T + M L I+ LS N
Sbjct: 304 YLKLDRNRIISIDNDTFENMGASLKILNLSFN 335
Score = 97.5 bits (232), Expect = 5e-19
Identities = 66/221 (29%), Positives = 107/221 (48%), Gaps = 2/221 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ L GIF+ L+NL+ L LQ N + + F + +++L N L L F
Sbjct: 117 NNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTF 176
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
L +D+SNN ++ + F L +L L L N + + + F LK+L+ L LS
Sbjct: 177 VGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLS 236
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N I I AF+ ++++N+ F+ + L L LS+N+L +L F
Sbjct: 237 HNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTF 296
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDC-FNLEKLDLSKNKL 221
LK L L L N + I ++TF + +L+ L+LS N L
Sbjct: 297 SLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNL 337
Score = 79.4 bits (187), Expect = 1e-13
Identities = 55/171 (32%), Positives = 86/171 (50%), Gaps = 2/171 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N++ + F+ L NL L L N L ++ S AF K L + LS+N + + F
Sbjct: 189 NNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAF 248
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
LE + + N+R+ V D F G+ +L+ L LS N ++N+ + TFS LKNL LKL
Sbjct: 249 KGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLD 308
Query: 122 DNKINNISDNAFEN-XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNN 171
N+I +I ++ FEN N L + ++ L LI L ++N
Sbjct: 309 RNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSN 359
Score = 76.6 bits (180), Expect = 9e-13
Identities = 48/175 (27%), Positives = 78/175 (44%)
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
L L+ N I+ I+++ D + + + + F L+ L FL L+NN + L
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLD 124
Query: 178 GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXX 237
F+ L LRNL L+ N +S +P F+D +++ L+L +N+L + F G
Sbjct: 125 PGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRI 184
Query: 238 XXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNP 292
+ F L+NL LYL N +PS + + L + LS NP
Sbjct: 185 LDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNP 239
>AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens
cDNA FLJ41026 fis, clone BRAMY2004771, weakly similar
to CHONDROADHERIN PRECURSOR. ).
Length = 622
Score = 123 bits (296), Expect = 8e-27
Identities = 89/331 (26%), Positives = 152/331 (45%), Gaps = 5/331 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ Y+ L +L L L + + + +AF + L+ + L+NN++ L +F
Sbjct: 70 NNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFK 129
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L + + N+V +VP F L S+Q L+L +N++ + +GTF + L+IL LS+
Sbjct: 130 GLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSN 189
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N I IS++ F++ N L +P+ F LK L L LS+N + ++ F+
Sbjct: 190 NNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFK 249
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L L L LK + + + + FS NL+ L LS N L +N F
Sbjct: 250 GLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDR 309
Query: 243 XXXYEVHFKAF-SMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALY 301
+ F +M +L L L N +L R L + L ++ + NPW C+C L
Sbjct: 310 NRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSNPWECNCKLLG 369
Query: 302 ISAWVRLNEMKIWDYSPTCVSPWYLEGHFLK 332
+ W+ + + + Y C +P + G L+
Sbjct: 370 LRDWLASSAITLNIY---CQNPPSMRGRALR 397
Score = 97.5 bits (232), Expect = 5e-19
Identities = 79/272 (29%), Positives = 115/272 (42%), Gaps = 4/272 (1%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSN-NYLYTLPEKLFANNTFLETIDISNNRVVYV 81
L L N + I+ T L + L N N LY P K F L + ++NN + +
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYP-KAFVQLRHLYFLFLNNNFIKRL 123
Query: 82 PSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXX 140
F GL +L+ L L N++ + G F+ L ++Q L L N++ + F
Sbjct: 124 DPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALR 183
Query: 141 XXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQI 200
N + I F +L+ L L L +NNL + FE LK LR L L N + I
Sbjct: 184 ILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAI 243
Query: 201 PDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLT 260
F NLE L L +++R + F G ++ FS+LKNL
Sbjct: 244 QPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLI 303
Query: 261 TLYLDGNMFPSLPSRTLDYM-PKLTIVKLSGN 291
L LD N S+ + T + M L I+ LS N
Sbjct: 304 YLKLDRNRIISIDNDTFENMGASLKILNLSFN 335
Score = 97.5 bits (232), Expect = 5e-19
Identities = 66/221 (29%), Positives = 107/221 (48%), Gaps = 2/221 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ L GIF+ L+NL+ L LQ N + + F + +++L N L L F
Sbjct: 117 NNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTF 176
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
L +D+SNN ++ + F L +L L L N + + + F LK+L+ L LS
Sbjct: 177 VGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLS 236
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N I I AF+ ++++N+ F+ + L L LS+N+L +L F
Sbjct: 237 HNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTF 296
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDC-FNLEKLDLSKNKL 221
LK L L L N + I ++TF + +L+ L+LS N L
Sbjct: 297 SLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNL 337
Score = 79.4 bits (187), Expect = 1e-13
Identities = 55/171 (32%), Positives = 86/171 (50%), Gaps = 2/171 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N++ + F+ L NL L L N L ++ S AF K L + LS+N + + F
Sbjct: 189 NNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAF 248
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
LE + + N+R+ V D F G+ +L+ L LS N ++N+ + TFS LKNL LKL
Sbjct: 249 KGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLD 308
Query: 122 DNKINNISDNAFEN-XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNN 171
N+I +I ++ FEN N L + ++ L LI L ++N
Sbjct: 309 RNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSN 359
Score = 76.6 bits (180), Expect = 9e-13
Identities = 48/175 (27%), Positives = 78/175 (44%)
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
L L+ N I+ I+++ D + + + + F L+ L FL L+NN + L
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLD 124
Query: 178 GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXX 237
F+ L LRNL L+ N +S +P F+D +++ L+L +N+L + F G
Sbjct: 125 PGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRI 184
Query: 238 XXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNP 292
+ F L+NL LYL N +PS + + L + LS NP
Sbjct: 185 LDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNP 239
>BC131897-1|AAI31898.1| 420|Homo sapiens LRRC4B protein protein.
Length = 420
Score = 122 bits (294), Expect = 1e-26
Identities = 86/283 (30%), Positives = 133/283 (46%), Gaps = 7/283 (2%)
Query: 54 LYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-L 112
L +P + N +L ++ N + + +D+F L L+IL LSKN ++ I+ G F+ L
Sbjct: 77 LAEVPASIPVNTRYL---NLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGL 133
Query: 113 KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSN-N 171
+L L+L DN++ + AFE N +++IP+ FN + L LDL
Sbjct: 134 PSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELK 193
Query: 172 NLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
L ++ FE L LR L+L L IP+ T LE+L+LS N+L I +F G
Sbjct: 194 RLEYISEAAFEGLVNLRYLNLGMCNLKDIPNLTA--LVRLEELELSGNRLDLIRPGSFQG 251
Query: 232 XXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ AF LK+L L L N SLP + +L V L+ N
Sbjct: 252 LTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHN 311
Query: 292 PWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKL 334
PWHC+C L++S W++ C +P L+G ++ +L
Sbjct: 312 PWHCNCDVLWLSWWLKETVPSNTTCCARCHAPAGLKGRYIGEL 354
Score = 80.6 bits (190), Expect = 6e-14
Identities = 64/206 (31%), Positives = 101/206 (49%), Gaps = 4/206 (1%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNR 77
VN + L LQ N ++ I ++ F + L + LS N + + F L T+++ +NR
Sbjct: 86 VNTRYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNR 145
Query: 78 VVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD-NKINNISDNAFEN 135
+ VP+ +F L L+ L L N I++I + F+ + +L+ L L + ++ IS+ AFE
Sbjct: 146 LTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEG 205
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
LK+IP L L L+LS N L + F+ L LR L L
Sbjct: 206 LVNLRYLNLGMCNLKDIPN--LTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHA 263
Query: 196 ALSQIPDNTFSDCFNLEKLDLSKNKL 221
++ I N F D +LE+L+LS N L
Sbjct: 264 QVATIERNAFDDLKSLEELNLSHNNL 289
Score = 73.7 bits (173), Expect = 6e-12
Identities = 58/219 (26%), Positives = 104/219 (47%), Gaps = 4/219 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ + F+ L +L+ L+L +N + +I+ AF L ++L +N L T+P + F
Sbjct: 95 ENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQAF 154
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSK-NKIQNIQNGTF-SLKNLQILKL 120
+ L + + NN + +PS +F + SL+ LDL + +++ I F L NL+ L L
Sbjct: 155 EYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNL 214
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
+ +I + N+L I F L L L L + + ++
Sbjct: 215 GMCNLKDIPN--LTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNA 272
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
F+ LK L L+L N L +P + F+ LE++ L+ N
Sbjct: 273 FDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHN 311
>BC032460-1|AAH32460.1| 634|Homo sapiens Unknown (protein for
IMAGE:5200456) protein.
Length = 634
Score = 122 bits (294), Expect = 1e-26
Identities = 86/283 (30%), Positives = 133/283 (46%), Gaps = 7/283 (2%)
Query: 54 LYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-L 112
L +P + N +L ++ N + + +D+F L L+IL LSKN ++ I+ G F+ L
Sbjct: 77 LAEVPASIPVNTRYL---NLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGL 133
Query: 113 KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSN-N 171
+L L+L DN++ + AFE N +++IP+ FN + L LDL
Sbjct: 134 PSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELK 193
Query: 172 NLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
L ++ FE L LR L+L L IP+ T LE+L+LS N+L I +F G
Sbjct: 194 RLEYISEAAFEGLVNLRYLNLGMCNLKDIPNLTA--LVRLEELELSGNRLDLIRPGSFQG 251
Query: 232 XXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ AF LK+L L L N SLP + +L V L+ N
Sbjct: 252 LTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHN 311
Query: 292 PWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKL 334
PWHC+C L++S W++ C +P L+G ++ +L
Sbjct: 312 PWHCNCDVLWLSWWLKETVPSNTTCCARCHAPAGLKGRYIGEL 354
Score = 80.6 bits (190), Expect = 6e-14
Identities = 64/206 (31%), Positives = 101/206 (49%), Gaps = 4/206 (1%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNR 77
VN + L LQ N ++ I ++ F + L + LS N + + F L T+++ +NR
Sbjct: 86 VNTRYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNR 145
Query: 78 VVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD-NKINNISDNAFEN 135
+ VP+ +F L L+ L L N I++I + F+ + +L+ L L + ++ IS+ AFE
Sbjct: 146 LTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEG 205
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
LK+IP L L L+LS N L + F+ L LR L L
Sbjct: 206 LVNLRYLNLGMCNLKDIPN--LTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHA 263
Query: 196 ALSQIPDNTFSDCFNLEKLDLSKNKL 221
++ I N F D +LE+L+LS N L
Sbjct: 264 QVATIERNAFDDLKSLEELNLSHNNL 289
Score = 73.7 bits (173), Expect = 6e-12
Identities = 58/219 (26%), Positives = 104/219 (47%), Gaps = 4/219 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ + F+ L +L+ L+L +N + +I+ AF L ++L +N L T+P + F
Sbjct: 95 ENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQAF 154
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSK-NKIQNIQNGTF-SLKNLQILKL 120
+ L + + NN + +PS +F + SL+ LDL + +++ I F L NL+ L L
Sbjct: 155 EYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNL 214
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
+ +I + N+L I F L L L L + + ++
Sbjct: 215 GMCNLKDIPN--LTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNA 272
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
F+ LK L L+L N L +P + F+ LE++ L+ N
Sbjct: 273 FDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHN 311
>BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth factor
binding protein, acid labile subunit protein.
Length = 605
Score = 121 bits (291), Expect = 3e-26
Identities = 89/276 (32%), Positives = 126/276 (45%), Gaps = 1/276 (0%)
Query: 17 LVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNN 76
L NL L L+RN L + F T L + LSNN L L + LF L +++ N
Sbjct: 121 LENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWN 180
Query: 77 RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFEN 135
+ +P +F GL SL+ L L+ N++ +Q FS L L+ L LS N + I N F
Sbjct: 181 SLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQ 240
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
DRN + + F LK L +LDLS+N + L F L LR L L N
Sbjct: 241 LPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHN 300
Query: 196 ALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSM 255
A++ + TF D LE+L L N++R + +F G EV AF
Sbjct: 301 AIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLG 360
Query: 256 LKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L N+ + L GN +LP + + KL + L G+
Sbjct: 361 LTNMAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGS 396
Score = 112 bits (270), Expect = 1e-23
Identities = 80/289 (27%), Positives = 128/289 (44%), Gaps = 1/289 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + YL +F L L+ L L RN L I + F +L + L N + + F
Sbjct: 204 NRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFL 263
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+S+NRV + D+F GL L++L LS N I +++ TF L L+ L+L
Sbjct: 264 GLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGH 323
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I +++ +FE D N+L+ + F L + ++LS N L +L F
Sbjct: 324 NRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNMAVMNLSGNCLRNLPEQVFR 383
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L L +L L+ + L +I +TF+ L +L L N L I + +G
Sbjct: 384 GLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTS 443
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + F L L L L N LP+ L + + + +S N
Sbjct: 444 NQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHN 492
Score = 101 bits (242), Expect = 3e-20
Identities = 76/289 (26%), Positives = 120/289 (41%), Gaps = 1/289 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + LP F L +L+ L L N L + F+ +L +DLS N L + +F
Sbjct: 180 NSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFV 239
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L+ + + N + V +FLGL +L+ LDLS N++ + TF L L++L+LS
Sbjct: 240 QLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSH 299
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N I ++ F++ N+++ + + F L L L L +N L + F
Sbjct: 300 NAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFL 359
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L + ++L N L +P+ F L L L + L I F G
Sbjct: 360 GLTNMAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKD 419
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ ++ L L L L N LP R + KL + LS N
Sbjct: 420 NGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRN 468
Score = 99.5 bits (237), Expect = 1e-19
Identities = 77/289 (26%), Positives = 123/289 (42%), Gaps = 1/289 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + + +F L L+ L L RN + + AF K L +DLS+N + L E F
Sbjct: 228 NALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFP 287
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L + +S+N + + +F L+ L+ L L N+I+ + +F L L++L L
Sbjct: 288 GLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDH 347
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N++ + AF N L+N+P Q+F L L L L + L + F
Sbjct: 348 NQLQEVKAGAFLGLTNMAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFT 407
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L LR L LK+N L I + + L +LDL+ N+L + F G
Sbjct: 408 GLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSR 467
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
E+ A L+ L + N +LP+ L + +L + L N
Sbjct: 468 NRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNN 516
Score = 99.1 bits (236), Expect = 1e-19
Identities = 78/295 (26%), Positives = 122/295 (41%), Gaps = 5/295 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + + G F L L+ L L N + + + F L + LS+N + +L + F
Sbjct: 252 NLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFK 311
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ FLE + + +NR+ + SF GL L++L L N++Q ++ G F L N+ ++ LS
Sbjct: 312 DLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNMAVMNLSG 371
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + N+ + F + + L I F L L L L +N L+ +
Sbjct: 372 NCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLW 431
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L L LDL N L+ +P F LE L LS+N+L + A
Sbjct: 432 GLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSH 491
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDC 297
+ + L L L L N + + P L + L GNPW C C
Sbjct: 492 NRLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQP----PGLERLWLEGNPWDCGC 542
Score = 97.5 bits (232), Expect = 5e-19
Identities = 78/290 (26%), Positives = 124/290 (42%), Gaps = 1/290 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + L G+FE L +L L L N L + AF L + L+ N L L LF
Sbjct: 155 NNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALF 214
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
+ L +D+S N + + ++ F+ L LQ L L +N I + G F LK L+ L LS
Sbjct: 215 SGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLS 274
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N++ + ++ F N + ++ + F +L L L L +N + LA F
Sbjct: 275 HNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSF 334
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXX 241
E L L L L N L ++ F N+ ++LS N LR + F G
Sbjct: 335 EGLGQLEVLTLDHNQLQEVKAGAFLGLTNMAVMNLSGNCLRNLPEQVFRGLGKLHSLHLE 394
Query: 242 XXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ F+ L L L+L N + ++L + +L + L+ N
Sbjct: 395 GSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSN 444
Score = 85.4 bits (202), Expect = 2e-15
Identities = 70/244 (28%), Positives = 103/244 (42%), Gaps = 1/244 (0%)
Query: 49 LSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNG 108
L N L ++P F N + L +++ ++ + + LGL +L L L +N+++++ G
Sbjct: 81 LDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALG 140
Query: 109 TFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLD 167
TF+ L L LS+N+++ + D FE N L +P F L L L
Sbjct: 141 TFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELV 200
Query: 168 LSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINIT 227
L+ N L L F L LR LDL NAL I N F L+KL L +N + +
Sbjct: 201 LAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPG 260
Query: 228 AFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVK 287
AF G + F L L L L N SL RT + L ++
Sbjct: 261 AFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQ 320
Query: 288 LSGN 291
L N
Sbjct: 321 LGHN 324
Score = 68.5 bits (160), Expect = 2e-10
Identities = 52/200 (26%), Positives = 84/200 (42%), Gaps = 1/200 (0%)
Query: 93 QILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN 151
Q L L N + ++ F +L +L L L ++ ++ A +RN+L++
Sbjct: 77 QALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRS 136
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNL 211
+ F + L L LSNN L L FE L L +L+L N+L+ +PD F +L
Sbjct: 137 LALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSL 196
Query: 212 EKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPS 271
+L L+ N+L ++ F G + F L L LYLD N+ +
Sbjct: 197 RELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAA 256
Query: 272 LPSRTLDYMPKLTIVKLSGN 291
+ + L + LS N
Sbjct: 257 VAPGAFLGLKALRWLDLSHN 276
>M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth factor
binding protein complex protein.
Length = 605
Score = 120 bits (290), Expect = 4e-26
Identities = 89/276 (32%), Positives = 126/276 (45%), Gaps = 1/276 (0%)
Query: 17 LVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNN 76
L NL L L+RN L + F T L + LSNN L L + LF L +++ N
Sbjct: 121 LENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWN 180
Query: 77 RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFEN 135
+ +P +F GL SL+ L L+ N++ +Q FS L L+ L LS N + I N F
Sbjct: 181 SLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQ 240
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
DRN + + F LK L +LDLS+N + L F L LR L L N
Sbjct: 241 LPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHN 300
Query: 196 ALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSM 255
A++ + TF D LE+L L N++R + +F G EV AF
Sbjct: 301 AIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLG 360
Query: 256 LKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L N+ + L GN +LP + + KL + L G+
Sbjct: 361 LTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGS 396
Score = 112 bits (269), Expect = 1e-23
Identities = 80/289 (27%), Positives = 128/289 (44%), Gaps = 1/289 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + YL +F L L+ L L RN L I + F +L + L N + + F
Sbjct: 204 NRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFL 263
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+S+NRV + D+F GL L++L LS N I +++ TF L L+ L+L
Sbjct: 264 GLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGH 323
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I +++ +FE D N+L+ + F L + ++LS N L +L F
Sbjct: 324 NRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFR 383
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L L +L L+ + L +I +TF+ L +L L N L I + +G
Sbjct: 384 GLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTS 443
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + F L L L L N LP+ L + + + +S N
Sbjct: 444 NQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHN 492
Score = 101 bits (241), Expect = 4e-20
Identities = 76/289 (26%), Positives = 120/289 (41%), Gaps = 1/289 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + LP F L +L+ L L N L + F+ +L +DLS N L + +F
Sbjct: 180 NSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFV 239
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L+ + + N + V +FLGL +L+ LDLS N++ + TF L L++L+LS
Sbjct: 240 QLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSH 299
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N I ++ F++ N+++ + + F L L L L +N L + F
Sbjct: 300 NAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFL 359
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L + ++L N L +P+ F L L L + L I F G
Sbjct: 360 GLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKD 419
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ ++ L L L L N LP R + KL + LS N
Sbjct: 420 NGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRN 468
Score = 99.5 bits (237), Expect = 1e-19
Identities = 77/289 (26%), Positives = 123/289 (42%), Gaps = 1/289 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + + +F L L+ L L RN + + AF K L +DLS+N + L E F
Sbjct: 228 NALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFP 287
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L + +S+N + + +F L+ L+ L L N+I+ + +F L L++L L
Sbjct: 288 GLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDH 347
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N++ + AF N L+N+P Q+F L L L L + L + F
Sbjct: 348 NQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFT 407
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L LR L LK+N L I + + L +LDL+ N+L + F G
Sbjct: 408 GLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSR 467
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
E+ A L+ L + N +LP+ L + +L + L N
Sbjct: 468 NRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNN 516
Score = 98.7 bits (235), Expect = 2e-19
Identities = 78/295 (26%), Positives = 122/295 (41%), Gaps = 5/295 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + + G F L L+ L L N + + + F L + LS+N + +L + F
Sbjct: 252 NLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFK 311
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ FLE + + +NR+ + SF GL L++L L N++Q ++ G F L N+ ++ LS
Sbjct: 312 DLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSG 371
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + N+ + F + + L I F L L L L +N L+ +
Sbjct: 372 NCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLW 431
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L L LDL N L+ +P F LE L LS+N+L + A
Sbjct: 432 GLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSH 491
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDC 297
+ + L L L L N + + P L + L GNPW C C
Sbjct: 492 NRLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQP----PGLERLWLEGNPWDCGC 542
Score = 97.1 bits (231), Expect = 6e-19
Identities = 78/290 (26%), Positives = 124/290 (42%), Gaps = 1/290 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + L G+FE L +L L L N L + AF L + L+ N L L LF
Sbjct: 155 NNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALF 214
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
+ L +D+S N + + ++ F+ L LQ L L +N I + G F LK L+ L LS
Sbjct: 215 SGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLS 274
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N++ + ++ F N + ++ + F +L L L L +N + LA F
Sbjct: 275 HNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSF 334
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXX 241
E L L L L N L ++ F N+ ++LS N LR + F G
Sbjct: 335 EGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLE 394
Query: 242 XXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ F+ L L L+L N + ++L + +L + L+ N
Sbjct: 395 GSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSN 444
Score = 85.4 bits (202), Expect = 2e-15
Identities = 70/244 (28%), Positives = 103/244 (42%), Gaps = 1/244 (0%)
Query: 49 LSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNG 108
L N L ++P F N + L +++ ++ + + LGL +L L L +N+++++ G
Sbjct: 81 LDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALG 140
Query: 109 TFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLD 167
TF+ L L LS+N+++ + D FE N L +P F L L L
Sbjct: 141 TFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELV 200
Query: 168 LSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINIT 227
L+ N L L F L LR LDL NAL I N F L+KL L +N + +
Sbjct: 201 LAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPG 260
Query: 228 AFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVK 287
AF G + F L L L L N SL RT + L ++
Sbjct: 261 AFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQ 320
Query: 288 LSGN 291
L N
Sbjct: 321 LGHN 324
Score = 68.5 bits (160), Expect = 2e-10
Identities = 52/200 (26%), Positives = 84/200 (42%), Gaps = 1/200 (0%)
Query: 93 QILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN 151
Q L L N + ++ F +L +L L L ++ ++ A +RN+L++
Sbjct: 77 QALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRS 136
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNL 211
+ F + L L LSNN L L FE L L +L+L N+L+ +PD F +L
Sbjct: 137 LALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSL 196
Query: 212 EKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPS 271
+L L+ N+L ++ F G + F L L LYLD N+ +
Sbjct: 197 RELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAA 256
Query: 272 LPSRTLDYMPKLTIVKLSGN 291
+ + L + LS N
Sbjct: 257 VAPGAFLGLKALRWLDLSHN 276
>AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like
growth factor binding protein, acid labile subunit)
protein.
Length = 605
Score = 120 bits (290), Expect = 4e-26
Identities = 89/276 (32%), Positives = 126/276 (45%), Gaps = 1/276 (0%)
Query: 17 LVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNN 76
L NL L L+RN L + F T L + LSNN L L + LF L +++ N
Sbjct: 121 LENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWN 180
Query: 77 RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFEN 135
+ +P +F GL SL+ L L+ N++ +Q FS L L+ L LS N + I N F
Sbjct: 181 SLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQ 240
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
DRN + + F LK L +LDLS+N + L F L LR L L N
Sbjct: 241 LPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHN 300
Query: 196 ALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSM 255
A++ + TF D LE+L L N++R + +F G EV AF
Sbjct: 301 AIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLG 360
Query: 256 LKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L N+ + L GN +LP + + KL + L G+
Sbjct: 361 LTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGS 396
Score = 112 bits (269), Expect = 1e-23
Identities = 80/289 (27%), Positives = 128/289 (44%), Gaps = 1/289 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + YL +F L L+ L L RN L I + F +L + L N + + F
Sbjct: 204 NRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFL 263
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+S+NRV + D+F GL L++L LS N I +++ TF L L+ L+L
Sbjct: 264 GLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGH 323
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I +++ +FE D N+L+ + F L + ++LS N L +L F
Sbjct: 324 NRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFR 383
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L L +L L+ + L +I +TF+ L +L L N L I + +G
Sbjct: 384 GLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTS 443
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + F L L L L N LP+ L + + + +S N
Sbjct: 444 NQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHN 492
Score = 101 bits (241), Expect = 4e-20
Identities = 76/289 (26%), Positives = 120/289 (41%), Gaps = 1/289 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + LP F L +L+ L L N L + F+ +L +DLS N L + +F
Sbjct: 180 NSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFV 239
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L+ + + N + V +FLGL +L+ LDLS N++ + TF L L++L+LS
Sbjct: 240 QLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSH 299
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N I ++ F++ N+++ + + F L L L L +N L + F
Sbjct: 300 NAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFL 359
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L + ++L N L +P+ F L L L + L I F G
Sbjct: 360 GLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKD 419
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ ++ L L L L N LP R + KL + LS N
Sbjct: 420 NGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRN 468
Score = 99.5 bits (237), Expect = 1e-19
Identities = 77/289 (26%), Positives = 123/289 (42%), Gaps = 1/289 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + + +F L L+ L L RN + + AF K L +DLS+N + L E F
Sbjct: 228 NALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFP 287
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L + +S+N + + +F L+ L+ L L N+I+ + +F L L++L L
Sbjct: 288 GLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDH 347
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N++ + AF N L+N+P Q+F L L L L + L + F
Sbjct: 348 NQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFT 407
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L LR L LK+N L I + + L +LDL+ N+L + F G
Sbjct: 408 GLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSR 467
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
E+ A L+ L + N +LP+ L + +L + L N
Sbjct: 468 NRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNN 516
Score = 98.7 bits (235), Expect = 2e-19
Identities = 78/295 (26%), Positives = 122/295 (41%), Gaps = 5/295 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + + G F L L+ L L N + + + F L + LS+N + +L + F
Sbjct: 252 NLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFK 311
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ FLE + + +NR+ + SF GL L++L L N++Q ++ G F L N+ ++ LS
Sbjct: 312 DLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSG 371
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + N+ + F + + L I F L L L L +N L+ +
Sbjct: 372 NCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLW 431
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L L LDL N L+ +P F LE L LS+N+L + A
Sbjct: 432 GLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSH 491
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDC 297
+ + L L L L N + + P L + L GNPW C C
Sbjct: 492 NRLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQP----PGLERLWLEGNPWDCGC 542
Score = 97.1 bits (231), Expect = 6e-19
Identities = 78/290 (26%), Positives = 124/290 (42%), Gaps = 1/290 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + L G+FE L +L L L N L + AF L + L+ N L L LF
Sbjct: 155 NNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALF 214
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
+ L +D+S N + + ++ F+ L LQ L L +N I + G F LK L+ L LS
Sbjct: 215 SGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLS 274
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N++ + ++ F N + ++ + F +L L L L +N + LA F
Sbjct: 275 HNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSF 334
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXX 241
E L L L L N L ++ F N+ ++LS N LR + F G
Sbjct: 335 EGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLE 394
Query: 242 XXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ F+ L L L+L N + ++L + +L + L+ N
Sbjct: 395 GSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSN 444
Score = 85.4 bits (202), Expect = 2e-15
Identities = 70/244 (28%), Positives = 103/244 (42%), Gaps = 1/244 (0%)
Query: 49 LSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNG 108
L N L ++P F N + L +++ ++ + + LGL +L L L +N+++++ G
Sbjct: 81 LDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALG 140
Query: 109 TFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLD 167
TF+ L L LS+N+++ + D FE N L +P F L L L
Sbjct: 141 TFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELV 200
Query: 168 LSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINIT 227
L+ N L L F L LR LDL NAL I N F L+KL L +N + +
Sbjct: 201 LAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPG 260
Query: 228 AFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVK 287
AF G + F L L L L N SL RT + L ++
Sbjct: 261 AFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQ 320
Query: 288 LSGN 291
L N
Sbjct: 321 LGHN 324
Score = 68.5 bits (160), Expect = 2e-10
Identities = 52/200 (26%), Positives = 84/200 (42%), Gaps = 1/200 (0%)
Query: 93 QILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN 151
Q L L N + ++ F +L +L L L ++ ++ A +RN+L++
Sbjct: 77 QALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRS 136
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNL 211
+ F + L L LSNN L L FE L L +L+L N+L+ +PD F +L
Sbjct: 137 LALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSL 196
Query: 212 EKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPS 271
+L L+ N+L ++ F G + F L L LYLD N+ +
Sbjct: 197 RELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAA 256
Query: 272 LPSRTLDYMPKLTIVKLSGN 291
+ + L + LS N
Sbjct: 257 VAPGAFLGLKALRWLDLSHN 276
>AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit
protein.
Length = 605
Score = 120 bits (290), Expect = 4e-26
Identities = 89/276 (32%), Positives = 126/276 (45%), Gaps = 1/276 (0%)
Query: 17 LVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNN 76
L NL L L+RN L + F T L + LSNN L L + LF L +++ N
Sbjct: 121 LENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWN 180
Query: 77 RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFEN 135
+ +P +F GL SL+ L L+ N++ +Q FS L L+ L LS N + I N F
Sbjct: 181 SLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQ 240
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
DRN + + F LK L +LDLS+N + L F L LR L L N
Sbjct: 241 LPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHN 300
Query: 196 ALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSM 255
A++ + TF D LE+L L N++R + +F G EV AF
Sbjct: 301 AIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLG 360
Query: 256 LKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L N+ + L GN +LP + + KL + L G+
Sbjct: 361 LTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGS 396
Score = 112 bits (269), Expect = 1e-23
Identities = 80/289 (27%), Positives = 128/289 (44%), Gaps = 1/289 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + YL +F L L+ L L RN L I + F +L + L N + + F
Sbjct: 204 NRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFL 263
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+S+NRV + D+F GL L++L LS N I +++ TF L L+ L+L
Sbjct: 264 GLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGH 323
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I +++ +FE D N+L+ + F L + ++LS N L +L F
Sbjct: 324 NRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFR 383
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L L +L L+ + L +I +TF+ L +L L N L I + +G
Sbjct: 384 GLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTS 443
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + F L L L L N LP+ L + + + +S N
Sbjct: 444 NQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHN 492
Score = 101 bits (241), Expect = 4e-20
Identities = 76/289 (26%), Positives = 120/289 (41%), Gaps = 1/289 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + LP F L +L+ L L N L + F+ +L +DLS N L + +F
Sbjct: 180 NSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFV 239
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L+ + + N + V +FLGL +L+ LDLS N++ + TF L L++L+LS
Sbjct: 240 QLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSH 299
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N I ++ F++ N+++ + + F L L L L +N L + F
Sbjct: 300 NAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFL 359
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L + ++L N L +P+ F L L L + L I F G
Sbjct: 360 GLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKD 419
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ ++ L L L L N LP R + KL + LS N
Sbjct: 420 NGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRN 468
Score = 99.5 bits (237), Expect = 1e-19
Identities = 77/289 (26%), Positives = 123/289 (42%), Gaps = 1/289 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + + +F L L+ L L RN + + AF K L +DLS+N + L E F
Sbjct: 228 NALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFP 287
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L + +S+N + + +F L+ L+ L L N+I+ + +F L L++L L
Sbjct: 288 GLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDH 347
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N++ + AF N L+N+P Q+F L L L L + L + F
Sbjct: 348 NQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFT 407
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L LR L LK+N L I + + L +LDL+ N+L + F G
Sbjct: 408 GLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSR 467
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
E+ A L+ L + N +LP+ L + +L + L N
Sbjct: 468 NRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNN 516
Score = 98.7 bits (235), Expect = 2e-19
Identities = 78/295 (26%), Positives = 122/295 (41%), Gaps = 5/295 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + + G F L L+ L L N + + + F L + LS+N + +L + F
Sbjct: 252 NLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFK 311
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ FLE + + +NR+ + SF GL L++L L N++Q ++ G F L N+ ++ LS
Sbjct: 312 DLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSG 371
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + N+ + F + + L I F L L L L +N L+ +
Sbjct: 372 NCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLW 431
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L L LDL N L+ +P F LE L LS+N+L + A
Sbjct: 432 GLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSH 491
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDC 297
+ + L L L L N + + P L + L GNPW C C
Sbjct: 492 NRLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQP----PGLERLWLEGNPWDCGC 542
Score = 97.1 bits (231), Expect = 6e-19
Identities = 78/290 (26%), Positives = 124/290 (42%), Gaps = 1/290 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + L G+FE L +L L L N L + AF L + L+ N L L LF
Sbjct: 155 NNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALF 214
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
+ L +D+S N + + ++ F+ L LQ L L +N I + G F LK L+ L LS
Sbjct: 215 SGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLS 274
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N++ + ++ F N + ++ + F +L L L L +N + LA F
Sbjct: 275 HNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSF 334
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXX 241
E L L L L N L ++ F N+ ++LS N LR + F G
Sbjct: 335 EGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLE 394
Query: 242 XXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ F+ L L L+L N + ++L + +L + L+ N
Sbjct: 395 GSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSN 444
Score = 85.4 bits (202), Expect = 2e-15
Identities = 70/244 (28%), Positives = 103/244 (42%), Gaps = 1/244 (0%)
Query: 49 LSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNG 108
L N L ++P F N + L +++ ++ + + LGL +L L L +N+++++ G
Sbjct: 81 LDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALG 140
Query: 109 TFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLD 167
TF+ L L LS+N+++ + D FE N L +P F L L L
Sbjct: 141 TFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELV 200
Query: 168 LSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINIT 227
L+ N L L F L LR LDL NAL I N F L+KL L +N + +
Sbjct: 201 LAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPG 260
Query: 228 AFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVK 287
AF G + F L L L L N SL RT + L ++
Sbjct: 261 AFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQ 320
Query: 288 LSGN 291
L N
Sbjct: 321 LGHN 324
Score = 68.5 bits (160), Expect = 2e-10
Identities = 52/200 (26%), Positives = 84/200 (42%), Gaps = 1/200 (0%)
Query: 93 QILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN 151
Q L L N + ++ F +L +L L L ++ ++ A +RN+L++
Sbjct: 77 QALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRS 136
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNL 211
+ F + L L LSNN L L FE L L +L+L N+L+ +PD F +L
Sbjct: 137 LALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSL 196
Query: 212 EKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPS 271
+L L+ N+L ++ F G + F L L LYLD N+ +
Sbjct: 197 RELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAA 256
Query: 272 LPSRTLDYMPKLTIVKLSGN 291
+ + L + LS N
Sbjct: 257 VAPGAFLGLKALRWLDLSHN 276
>Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V
precursor protein.
Length = 560
Score = 116 bits (279), Expect = 9e-25
Identities = 91/323 (28%), Positives = 137/323 (42%), Gaps = 3/323 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + + +F+ LVNL+ L L +N L+ + + FT+ + L +DLS N L LP+ L
Sbjct: 132 NALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLG 191
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
LE + + +NR+V + S L +L L +N I++I G F L NL L LS
Sbjct: 192 AQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSR 251
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + + F + N L +P LF + L L L+ L +L F
Sbjct: 252 NHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFR 311
Query: 183 SLKLLRNLDLKENA-LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXX 241
+L LR L + + LS +P F L+ L L N L + G
Sbjct: 312 NLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLR 371
Query: 242 XXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALY 301
+ F L +L ++ LD N +LP +P+LT V L N W CDC
Sbjct: 372 RNRLRALPRALFRNLSSLESVQLDHNQLETLPGDVFGALPRLTEVLLGHNSWRCDCGLGP 431
Query: 302 ISAWVRLNEMKI-WDYSPTCVSP 323
W+R + + + P C P
Sbjct: 432 FLGWLRQHLGLVGGEEPPRCAGP 454
Score = 103 bits (248), Expect = 5e-21
Identities = 77/291 (26%), Positives = 128/291 (43%), Gaps = 2/291 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
D+H+ + G F L+ LKTLRL RN + + L + L +N L + + +F
Sbjct: 83 DSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLFLDHNALRGIDQNMF 142
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLK-NLQILKLS 121
L+ + ++ N++ ++P+ F L +L++LDLS N + ++ G + L+ L L
Sbjct: 143 QKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLGAQAKLERLLLH 202
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N++ ++ + RN +++I F+ L L L LS N+L L F
Sbjct: 203 SNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSALF 262
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXX 241
L L L EN L+++P F + L++L L++ +LR + AF
Sbjct: 263 LHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVT 322
Query: 242 XXXXYE-VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ AF L L L L N +LP L + KL V L N
Sbjct: 323 LSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRN 373
Score = 74.1 bits (174), Expect = 5e-12
Identities = 57/224 (25%), Positives = 97/224 (43%), Gaps = 2/224 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ N + L G+ SL L L+ RN++ I AF L + LS N+L LP
Sbjct: 201 LHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSA 260
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILK 119
LF ++ L + + N + +P F + LQ L L++ +++ + F +L L+ L
Sbjct: 261 LFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLG 320
Query: 120 LS-DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
++ +++ + AF+ N L +P L L L + L N L +L
Sbjct: 321 VTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPR 380
Query: 179 VEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
F +L L ++ L N L +P + F L ++ L N R
Sbjct: 381 ALFRNLSSLESVQLDHNQLETLPGDVFGALPRLTEVLLGHNSWR 424
Score = 62.5 bits (145), Expect = 2e-08
Identities = 49/188 (26%), Positives = 81/188 (43%), Gaps = 1/188 (0%)
Query: 105 IQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCL 163
+Q+ +FS + LQ L +SD+ I+ ++ F + RNK+ ++P L + + L
Sbjct: 65 LQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLL 124
Query: 164 IFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRF 223
L L +N L + F+ L L+ L L +N L +P + F++ NL+ LDLS N L
Sbjct: 125 EQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTH 184
Query: 224 INITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKL 283
+ + + L LT L N S+ D +P L
Sbjct: 185 LPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNL 244
Query: 284 TIVKLSGN 291
+ + LS N
Sbjct: 245 SSLTLSRN 252
>L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane
glycoprotein V protein.
Length = 560
Score = 116 bits (279), Expect = 9e-25
Identities = 91/323 (28%), Positives = 137/323 (42%), Gaps = 3/323 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + + +F+ LVNL+ L L +N L+ + + FT+ + L +DLS N L LP+ L
Sbjct: 132 NALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLG 191
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
LE + + +NR+V + S L +L L +N I++I G F L NL L LS
Sbjct: 192 AQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSR 251
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + + F + N L +P LF + L L L+ L +L F
Sbjct: 252 NHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFR 311
Query: 183 SLKLLRNLDLKENA-LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXX 241
+L LR L + + LS +P F L+ L L N L + G
Sbjct: 312 NLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLR 371
Query: 242 XXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALY 301
+ F L +L ++ LD N +LP +P+LT V L N W CDC
Sbjct: 372 RNRLRALPRALFRNLSSLESVQLDHNQLETLPGDVFGALPRLTEVLLGHNSWRCDCGLGP 431
Query: 302 ISAWVRLNEMKI-WDYSPTCVSP 323
W+R + + + P C P
Sbjct: 432 FLGWLRQHLGLVGGEEPPRCAGP 454
Score = 103 bits (248), Expect = 5e-21
Identities = 77/291 (26%), Positives = 128/291 (43%), Gaps = 2/291 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
D+H+ + G F L+ LKTLRL RN + + L + L +N L + + +F
Sbjct: 83 DSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLFLDHNALRGIDQNMF 142
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLK-NLQILKLS 121
L+ + ++ N++ ++P+ F L +L++LDLS N + ++ G + L+ L L
Sbjct: 143 QKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLGAQAKLERLLLH 202
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N++ ++ + RN +++I F+ L L L LS N+L L F
Sbjct: 203 SNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSALF 262
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXX 241
L L L EN L+++P F + L++L L++ +LR + AF
Sbjct: 263 LHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVT 322
Query: 242 XXXXYE-VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ AF L L L L N +LP L + KL V L N
Sbjct: 323 LSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRN 373
Score = 74.1 bits (174), Expect = 5e-12
Identities = 57/224 (25%), Positives = 97/224 (43%), Gaps = 2/224 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ N + L G+ SL L L+ RN++ I AF L + LS N+L LP
Sbjct: 201 LHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSA 260
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILK 119
LF ++ L + + N + +P F + LQ L L++ +++ + F +L L+ L
Sbjct: 261 LFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLG 320
Query: 120 LS-DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
++ +++ + AF+ N L +P L L L + L N L +L
Sbjct: 321 VTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPR 380
Query: 179 VEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
F +L L ++ L N L +P + F L ++ L N R
Sbjct: 381 ALFRNLSSLESVQLDHNQLETLPGDVFGALPRLTEVLLGHNSWR 424
Score = 62.5 bits (145), Expect = 2e-08
Identities = 49/188 (26%), Positives = 81/188 (43%), Gaps = 1/188 (0%)
Query: 105 IQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCL 163
+Q+ +FS + LQ L +SD+ I+ ++ F + RNK+ ++P L + + L
Sbjct: 65 LQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLL 124
Query: 164 IFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRF 223
L L +N L + F+ L L+ L L +N L +P + F++ NL+ LDLS N L
Sbjct: 125 EQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTH 184
Query: 224 INITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKL 283
+ + + L LT L N S+ D +P L
Sbjct: 185 LPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNL 244
Query: 284 TIVKLSGN 291
+ + LS N
Sbjct: 245 SSLTLSRN 252
>BC117276-1|AAI17277.1| 420|Homo sapiens reticulon 4 receptor-like
2 protein.
Length = 420
Score = 116 bits (278), Expect = 1e-24
Identities = 80/246 (32%), Positives = 110/246 (44%), Gaps = 4/246 (1%)
Query: 91 SLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNK-L 149
S Q L L N I+ ++ GTF NL L L N ++ I F + N+ L
Sbjct: 61 STQRLFLQNNLIRTLRPGTFG-SNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHL 119
Query: 150 KNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCF 209
+++ F L+ L L L L SL G F L L+ L L+EN+L + D+ F+D
Sbjct: 120 RSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLA 179
Query: 210 NLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
NL L L N+LR + F G VH AF L LT LYL N
Sbjct: 180 NLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSL 239
Query: 270 PSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGH 329
SLP L +P L ++L+ NPW CDC A + AW ++ TC +P +G
Sbjct: 240 ASLPGEALADLPSLEFLRLNANPWACDCRARPLWAW--FQRARVSSSDVTCATPPERQGR 297
Query: 330 FLKKLK 335
L+ L+
Sbjct: 298 DLRALR 303
Score = 59.7 bits (138), Expect = 1e-07
Identities = 39/116 (33%), Positives = 58/116 (50%), Gaps = 1/116 (0%)
Query: 9 LPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFL 68
LPG IF LV+L+ L LQ N L + + F L H+ L N L L E +F L
Sbjct: 146 LPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSL 205
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDN 123
+ + + NR+ V +F GL L IL L N + ++ + L +L+ L+L+ N
Sbjct: 206 DRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 54.0 bits (124), Expect = 6e-06
Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 1/131 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+ H+ L F+ L L++L L R L + F L ++ L N L L + LF
Sbjct: 116 NRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLF 175
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
A+ L + + NR+ + F GL SL L L N++Q + F L L IL L
Sbjct: 176 ADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLF 235
Query: 122 DNKINNISDNA 132
+N + ++ A
Sbjct: 236 NNSLASLPGEA 246
>BC113673-1|AAI13674.1| 420|Homo sapiens reticulon 4 receptor-like
2 protein.
Length = 420
Score = 116 bits (278), Expect = 1e-24
Identities = 80/246 (32%), Positives = 110/246 (44%), Gaps = 4/246 (1%)
Query: 91 SLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNK-L 149
S Q L L N I+ ++ GTF NL L L N ++ I F + N+ L
Sbjct: 61 STQRLFLQNNLIRTLRPGTFG-SNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHL 119
Query: 150 KNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCF 209
+++ F L+ L L L L SL G F L L+ L L+EN+L + D+ F+D
Sbjct: 120 RSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLA 179
Query: 210 NLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
NL L L N+LR + F G VH AF L LT LYL N
Sbjct: 180 NLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSL 239
Query: 270 PSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGH 329
SLP L +P L ++L+ NPW CDC A + AW ++ TC +P +G
Sbjct: 240 ASLPGEALADLPSLEFLRLNANPWACDCRARPLWAW--FQRARVSSSDVTCATPPERQGR 297
Query: 330 FLKKLK 335
L+ L+
Sbjct: 298 DLRALR 303
Score = 59.7 bits (138), Expect = 1e-07
Identities = 39/116 (33%), Positives = 58/116 (50%), Gaps = 1/116 (0%)
Query: 9 LPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFL 68
LPG IF LV+L+ L LQ N L + + F L H+ L N L L E +F L
Sbjct: 146 LPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSL 205
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDN 123
+ + + NR+ V +F GL L IL L N + ++ + L +L+ L+L+ N
Sbjct: 206 DRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 54.0 bits (124), Expect = 6e-06
Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 1/131 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+ H+ L F+ L L++L L R L + F L ++ L N L L + LF
Sbjct: 116 NRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLF 175
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
A+ L + + NR+ + F GL SL L L N++Q + F L L IL L
Sbjct: 176 ADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLF 235
Query: 122 DNKINNISDNA 132
+N + ++ A
Sbjct: 236 NNSLASLPGEA 246
>AF532858-1|AAP21835.1| 420|Homo sapiens Nogo-66 receptor homolog-1
protein.
Length = 420
Score = 116 bits (278), Expect = 1e-24
Identities = 80/246 (32%), Positives = 110/246 (44%), Gaps = 4/246 (1%)
Query: 91 SLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNK-L 149
S Q L L N I+ ++ GTF NL L L N ++ I F + N+ L
Sbjct: 61 STQRLFLQNNLIRTLRPGTFG-SNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHL 119
Query: 150 KNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCF 209
+++ F L+ L L L L SL G F L L+ L L+EN+L + D+ F+D
Sbjct: 120 RSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLA 179
Query: 210 NLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
NL L L N+LR + F G VH AF L LT LYL N
Sbjct: 180 NLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSL 239
Query: 270 PSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGH 329
SLP L +P L ++L+ NPW CDC A + AW ++ TC +P +G
Sbjct: 240 ASLPGEALADLPSLEFLRLNANPWACDCRARPLWAW--FQRARVSSSDVTCATPPERQGR 297
Query: 330 FLKKLK 335
L+ L+
Sbjct: 298 DLRALR 303
Score = 59.7 bits (138), Expect = 1e-07
Identities = 39/116 (33%), Positives = 58/116 (50%), Gaps = 1/116 (0%)
Query: 9 LPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFL 68
LPG IF LV+L+ L LQ N L + + F L H+ L N L L E +F L
Sbjct: 146 LPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSL 205
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDN 123
+ + + NR+ V +F GL L IL L N + ++ + L +L+ L+L+ N
Sbjct: 206 DRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 54.0 bits (124), Expect = 6e-06
Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 1/131 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+ H+ L F+ L L++L L R L + F L ++ L N L L + LF
Sbjct: 116 NRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLF 175
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
A+ L + + NR+ + F GL SL L L N++Q + F L L IL L
Sbjct: 176 ADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLF 235
Query: 122 DNKINNISDNA 132
+N + ++ A
Sbjct: 236 NNSLASLPGEA 246
>AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich
repeat-containing G protein-coupled receptor 4 precursor
variant protein.
Length = 1032
Score = 116 bits (278), Expect = 1e-24
Identities = 89/303 (29%), Positives = 135/303 (44%), Gaps = 8/303 (2%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ LP F++ L+ L+L N L I +A + K+L + L NN L T+P +
Sbjct: 148 NNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIR 207
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
+ L+++ + N + VP DSF GL L+ L L N + + S L LQ L L+
Sbjct: 208 GLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLAL 267
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
NKI++I D AF N NK++++ F+ L L LDL+ NNL +
Sbjct: 268 NKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQA-IK 326
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
+L L+ L N++S IPD F L + L N L F+ +AF+
Sbjct: 327 ALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRG 386
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN-----PWHCDC 297
+ F + +L +L L G S+P+ L + LS N P C
Sbjct: 387 ASMVQ-QFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGC 445
Query: 298 HAL 300
HAL
Sbjct: 446 HAL 448
Score = 100 bits (239), Expect = 6e-20
Identities = 82/306 (26%), Positives = 137/306 (44%), Gaps = 25/306 (8%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ +P FE LV L+ L L N L E+ ++ L + L+ N + ++P+ F
Sbjct: 220 NHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFT 279
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
N + L + + NN++ + F GL +L+ LDL+ N + +L +L+ L N
Sbjct: 280 NLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSLKELGFHSN 339
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLM----SLAG- 178
I+ I D AF+ N L + F+NL L L + +++ +L G
Sbjct: 340 SISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGT 399
Query: 179 VEFESL------------------KLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
V ESL K+LR LDL N + +P +F+ C LE++ L +N+
Sbjct: 400 VHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLP--SFNGCHALEEISLQRNQ 457
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ I F G +E+H +AF+ L +T L + N S P+ L+ +
Sbjct: 458 IYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGL 517
Query: 281 PKLTIV 286
+L +V
Sbjct: 518 NQLKLV 523
Score = 92.3 bits (219), Expect = 2e-17
Identities = 76/277 (27%), Positives = 118/277 (42%), Gaps = 6/277 (2%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
+ L + N + ++ +AF + L + L+ N L + K + L+ + + NN++
Sbjct: 141 QALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKT 200
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXX 139
VPS++ GL +LQ L L N I ++ +F L L+ L L DN + + + N
Sbjct: 201 VPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTL 260
Query: 140 XXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ 199
NK+ +IP F NL L+ L L NN + SL+ F+ L L LDL N L +
Sbjct: 261 QALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGE 320
Query: 200 IPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNL 259
P +L++L N + I AF G V AF L +L
Sbjct: 321 FP-QAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDL 379
Query: 260 TTLYLDG----NMFPSLPSRTLDYMPKLTIVKLSGNP 292
+L + G FP+L LT K+S P
Sbjct: 380 HSLVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIP 416
Score = 91.5 bits (217), Expect = 3e-17
Identities = 70/247 (28%), Positives = 104/247 (42%), Gaps = 5/247 (2%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
VD S L +PE L A F + +DIS N + +P D+F L+ L L+ N + I
Sbjct: 122 VDCSGKGLTAVPEGLSA---FTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIH 178
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
S LK L++L L +N++ + A D N + ++P F L L
Sbjct: 179 PKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRH 238
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
L L +N+L + +L L+ L L N +S IPD F++ +L L L NK+R ++
Sbjct: 239 LWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLS 298
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
F G E +A L +L L N +P D P L
Sbjct: 299 QHCFDGLDNLETLDLNYNNLGEFP-QAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRT 357
Query: 286 VKLSGNP 292
+ L NP
Sbjct: 358 IHLYDNP 364
Score = 77.4 bits (182), Expect = 5e-13
Identities = 75/313 (23%), Positives = 130/313 (41%), Gaps = 27/313 (8%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ +P L L++LRL N++ + ++F +L H+ L +N L +P
Sbjct: 195 NNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPL 254
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
+N L+ + ++ N++ +P +F L SL +L L NKI+++ F L NL+ L L+
Sbjct: 255 SNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLN 314
Query: 122 -----------------------DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFN 158
N I+ I D AF+ N L + F+
Sbjct: 315 YNNLGEFPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFH 374
Query: 159 NLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSK 218
NL L L + +++ L +L L +S IP+N + L LDLS
Sbjct: 375 NLSDLHSLVIRGASMVQ-QFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSY 433
Query: 219 NKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLD 278
N +R ++ +F G Y++ F L +L L L N+ + SR
Sbjct: 434 NNIR--DLPSFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFA 491
Query: 279 YMPKLTIVKLSGN 291
+ +T + +S N
Sbjct: 492 TLGPITNLDVSFN 504
Score = 44.0 bits (99), Expect = 0.006
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 2/114 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ LP F L+ + LQRN + +I F L +DLS N ++ + + FA
Sbjct: 434 NNIRDLPS--FNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFA 491
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQI 117
+ +D+S N + P++ GL L+++ K K +L++L +
Sbjct: 492 TLGPITNLDVSFNELTSFPTEGLNGLNQLKLVGNFKLKEALAAKDFVNLRSLSV 545
>BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 115 bits (277), Expect = 2e-24
Identities = 85/289 (29%), Positives = 132/289 (45%), Gaps = 8/289 (2%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ Y+P F L +L+ L L N L EI +AF S L + L+ N ++ +P+ F
Sbjct: 148 NHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFG 207
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
N + L + + NNR+ + F GL+SL+ LDL+ N + +L NL+ L DN
Sbjct: 208 NLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELHFYDN 267
Query: 124 KINNISDNAFENXXXXXXXXXD-RNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
I + +AF++ + +++ P L L L+ + SL
Sbjct: 268 PIQFVGRSAFQHLPELRTLTLNGASQITEFPD--LTGTANLESLTLTGAQISSLPQTVCN 325
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L L+ LDL N L +P +FS C L+K+DL N++ I + F
Sbjct: 326 QLPNLQVLDLSYNLLEDLP--SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAW 383
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+H AFS L +L L L N+ S P + + LT +KL+GN
Sbjct: 384 NKIAIIHPNAFSTLPSLIKLDLSSNLLSSFP---ITGLHGLTHLKLTGN 429
Score = 108 bits (259), Expect = 2e-22
Identities = 78/270 (28%), Positives = 118/270 (43%), Gaps = 3/270 (1%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
L L N + ++ S + L + L+ N L +P+ F L+ + + NN++ +VP
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXX 141
+++ L SLQ L L N I + FS L +L+ L L DN + I AF +
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQA 190
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
NK+ +IP F NL L+ L L NN + SL F+ L L LDL N L + P
Sbjct: 191 MTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP 250
Query: 202 DNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT 261
NL++L N ++F+ +AF F + NL +
Sbjct: 251 -TAIRTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNGASQI-TEFPDLTGTANLES 308
Query: 262 LYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L L G SLP + +P L ++ LS N
Sbjct: 309 LTLTGAQISSLPQTVCNQLPNLQVLDLSYN 338
Score = 96.3 bits (229), Expect = 1e-18
Identities = 83/311 (26%), Positives = 134/311 (43%), Gaps = 25/311 (8%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + Y+P G F L +LK L LQ N L + +EA + + L + L N++ +P F+
Sbjct: 100 NALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFS 159
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L + + +N + +P +F L +LQ + L+ NKI +I + F +L +L +L L +
Sbjct: 160 GLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHN 219
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQL--FNNLKCLIFLD------------- 167
N+I+++ F+ + N L PT + +NLK L F D
Sbjct: 220 NRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELHFYDNPIQFVGRSAFQH 279
Query: 168 LSNNNLMSLAG----VEFESLKLLRNLD---LKENALSQIPDNTFSDCFNLEKLDLSKNK 220
L ++L G EF L NL+ L +S +P + NL+ LDLS N
Sbjct: 280 LPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNL 339
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
L ++ +F YE+ F L +L +L L N + +
Sbjct: 340 LE--DLPSFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTL 397
Query: 281 PKLTIVKLSGN 291
P L + LS N
Sbjct: 398 PSLIKLDLSSN 408
Score = 91.9 bits (218), Expect = 2e-17
Identities = 77/272 (28%), Positives = 113/272 (41%), Gaps = 3/272 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ L SL L+ LRL N L I AFT L + L NN L +P +
Sbjct: 76 NNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQ 135
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
N L+++ + N + YVP F GL+SL+ L L N + I F SL LQ + L+
Sbjct: 136 NLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLAL 195
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
NKI++I D AF N N++ ++ + F+ L L LDL+ NNL
Sbjct: 196 NKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP-TAIR 254
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
+L L+ L +N + + + F L L L+ + G
Sbjct: 255 TLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLN-GASQITEFPDLTGTANLESLTLTG 313
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPS 274
+ + L NL L L N+ LPS
Sbjct: 314 AQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS 345
Score = 82.2 bits (194), Expect = 2e-14
Identities = 64/250 (25%), Positives = 105/250 (42%), Gaps = 5/250 (2%)
Query: 42 KKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNK 101
+ L VD S+ L LP L + F +D+S N + + + L L+ L L+ N
Sbjct: 45 RMLLRVDCSDLGLSELPSNL---SVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNA 101
Query: 102 IQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNL 160
+ I G F+ L +L++L L +N++ ++ A +N D N + +P F+ L
Sbjct: 102 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGL 161
Query: 161 KCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
L L L +N L + F SL L+ + L N + IPD F + +L L L N+
Sbjct: 162 HSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNR 221
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ + F G E A L NL L+ N + ++
Sbjct: 222 IHSLGKKCFDGLHSLETLDLNYNNLDEFP-TAIRTLSNLKELHFYDNPIQFVGRSAFQHL 280
Query: 281 PKLTIVKLSG 290
P+L + L+G
Sbjct: 281 PELRTLTLNG 290
Score = 59.7 bits (138), Expect = 1e-07
Identities = 58/190 (30%), Positives = 89/190 (46%), Gaps = 11/190 (5%)
Query: 2 FDNHVEYLPGGIFESLVNLKTLRLQRNYLEEI-DSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+DN ++++ F+ L L+TL L N +I + T T L + L+ + +LP+
Sbjct: 265 YDNPIQFVGRSAFQHLPELRTLTL--NGASQITEFPDLTGTANLESLTLTGAQISSLPQT 322
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILK 119
+ L+ +D+S N + +P SF LQ +DL N+I I+ TF L +L+ L
Sbjct: 323 VCNQLPNLQVLDLSYNLLEDLP--SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLN 380
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNN-LMSLAG 178
L+ NKI I NAF N L + P L L L L+ N+ L SL
Sbjct: 381 LAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFP---ITGLHGLTHLKLTGNHALQSLIS 437
Query: 179 VE-FESLKLL 187
E F LK++
Sbjct: 438 SENFPELKVI 447
>BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 115 bits (277), Expect = 2e-24
Identities = 85/289 (29%), Positives = 132/289 (45%), Gaps = 8/289 (2%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ Y+P F L +L+ L L N L EI +AF S L + L+ N ++ +P+ F
Sbjct: 148 NHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFG 207
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
N + L + + NNR+ + F GL+SL+ LDL+ N + +L NL+ L DN
Sbjct: 208 NLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELHFYDN 267
Query: 124 KINNISDNAFENXXXXXXXXXD-RNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
I + +AF++ + +++ P L L L+ + SL
Sbjct: 268 PIQFVGRSAFQHLPELRTLTLNGASQITEFPD--LTGTANLESLTLTGAQISSLPQTVCN 325
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L L+ LDL N L +P +FS C L+K+DL N++ I + F
Sbjct: 326 QLPNLQVLDLSYNLLEDLP--SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAW 383
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+H AFS L +L L L N+ S P + + LT +KL+GN
Sbjct: 384 NKIAIIHPNAFSTLPSLIKLDLSSNLLSSFP---ITGLHGLTHLKLTGN 429
Score = 108 bits (259), Expect = 2e-22
Identities = 78/270 (28%), Positives = 118/270 (43%), Gaps = 3/270 (1%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
L L N + ++ S + L + L+ N L +P+ F L+ + + NN++ +VP
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXX 141
+++ L SLQ L L N I + FS L +L+ L L DN + I AF +
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQA 190
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
NK+ +IP F NL L+ L L NN + SL F+ L L LDL N L + P
Sbjct: 191 MTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP 250
Query: 202 DNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT 261
NL++L N ++F+ +AF F + NL +
Sbjct: 251 -TAIRTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNGASQI-TEFPDLTGTANLES 308
Query: 262 LYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L L G SLP + +P L ++ LS N
Sbjct: 309 LTLTGAQISSLPQTVCNQLPNLQVLDLSYN 338
Score = 96.3 bits (229), Expect = 1e-18
Identities = 83/311 (26%), Positives = 134/311 (43%), Gaps = 25/311 (8%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + Y+P G F L +LK L LQ N L + +EA + + L + L N++ +P F+
Sbjct: 100 NALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFS 159
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L + + +N + +P +F L +LQ + L+ NKI +I + F +L +L +L L +
Sbjct: 160 GLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHN 219
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQL--FNNLKCLIFLD------------- 167
N+I+++ F+ + N L PT + +NLK L F D
Sbjct: 220 NRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELHFYDNPIQFVGRSAFQH 279
Query: 168 LSNNNLMSLAG----VEFESLKLLRNLD---LKENALSQIPDNTFSDCFNLEKLDLSKNK 220
L ++L G EF L NL+ L +S +P + NL+ LDLS N
Sbjct: 280 LPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNL 339
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
L ++ +F YE+ F L +L +L L N + +
Sbjct: 340 LE--DLPSFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTL 397
Query: 281 PKLTIVKLSGN 291
P L + LS N
Sbjct: 398 PSLIKLDLSSN 408
Score = 91.9 bits (218), Expect = 2e-17
Identities = 77/272 (28%), Positives = 113/272 (41%), Gaps = 3/272 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ L SL L+ LRL N L I AFT L + L NN L +P +
Sbjct: 76 NNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQ 135
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
N L+++ + N + YVP F GL+SL+ L L N + I F SL LQ + L+
Sbjct: 136 NLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLAL 195
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
NKI++I D AF N N++ ++ + F+ L L LDL+ NNL
Sbjct: 196 NKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP-TAIR 254
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
+L L+ L +N + + + F L L L+ + G
Sbjct: 255 TLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLN-GASQITEFPDLTGTANLESLTLTG 313
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPS 274
+ + L NL L L N+ LPS
Sbjct: 314 AQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS 345
Score = 82.2 bits (194), Expect = 2e-14
Identities = 64/250 (25%), Positives = 105/250 (42%), Gaps = 5/250 (2%)
Query: 42 KKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNK 101
+ L VD S+ L LP L + F +D+S N + + + L L+ L L+ N
Sbjct: 45 RMLLRVDCSDLGLSELPSNL---SVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNA 101
Query: 102 IQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNL 160
+ I G F+ L +L++L L +N++ ++ A +N D N + +P F+ L
Sbjct: 102 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGL 161
Query: 161 KCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
L L L +N L + F SL L+ + L N + IPD F + +L L L N+
Sbjct: 162 HSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNR 221
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ + F G E A L NL L+ N + ++
Sbjct: 222 IHSLGKKCFDGLHSLETLDLNYNNLDEFP-TAIRTLSNLKELHFYDNPIQFVGRSAFQHL 280
Query: 281 PKLTIVKLSG 290
P+L + L+G
Sbjct: 281 PELRTLTLNG 290
Score = 59.7 bits (138), Expect = 1e-07
Identities = 58/190 (30%), Positives = 89/190 (46%), Gaps = 11/190 (5%)
Query: 2 FDNHVEYLPGGIFESLVNLKTLRLQRNYLEEI-DSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+DN ++++ F+ L L+TL L N +I + T T L + L+ + +LP+
Sbjct: 265 YDNPIQFVGRSAFQHLPELRTLTL--NGASQITEFPDLTGTANLESLTLTGAQISSLPQT 322
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILK 119
+ L+ +D+S N + +P SF LQ +DL N+I I+ TF L +L+ L
Sbjct: 323 VCNQLPNLQVLDLSYNLLEDLP--SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLN 380
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNN-LMSLAG 178
L+ NKI I NAF N L + P L L L L+ N+ L SL
Sbjct: 381 LAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFP---ITGLHGLTHLKLTGNHALQSLIS 437
Query: 179 VE-FESLKLL 187
E F LK++
Sbjct: 438 SENFPELKVI 447
>BC035133-1|AAH35133.1| 708|Homo sapiens leucine rich repeat
neuronal 3 protein.
Length = 708
Score = 114 bits (274), Expect = 4e-24
Identities = 103/403 (25%), Positives = 177/403 (43%), Gaps = 22/403 (5%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNR 77
VNL +L L +N L + + +L V L N L LPEK + + L+ + I++N
Sbjct: 92 VNLTSLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNL 151
Query: 78 VVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENX 136
+ + +F+GL++L L L+ N++Q I + F +L NL+IL + +N I I D F+
Sbjct: 152 LSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPL 211
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
L IP L+ L + +N L+ + V + + L+ LDL +N
Sbjct: 212 INLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNP 271
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF----YGXXXXXXXXXXXXXXYEVHFKA 252
+++I FS+ +L++L ++ N I+I + Y +H A
Sbjct: 272 INRIRRGDFSNMLHLKELGIN-NMPELISIDSLAVDNLPDLRKIEATNNPRLSY-IHPNA 329
Query: 253 FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMK 312
F L L +L L+ N +L T++ +P L + + NP CDC + W+ +N+
Sbjct: 330 FFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDC----VIRWMNMNKTN 385
Query: 313 IWDYSPT---CVSPWYLEGHFLKKLKF---PELCAGQWASMVNLSPRLPIQQLLALNVSV 366
I P CV P +G ++++ F E+C A + L ++ ++
Sbjct: 386 IRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPLIAP-ESFPSNLNVEAGSYVSFHC 444
Query: 367 N-RCQMDGVIMWPIPVSESILD---THTGYVLDRGTTDIEDIT 405
+ I W P + +L T YV GT DI +T
Sbjct: 445 RATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVT 487
Score = 60.5 bits (140), Expect = 6e-08
Identities = 56/224 (25%), Positives = 104/224 (46%), Gaps = 11/224 (4%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ + F++L NL+ L + N + I F L + ++ L +P+
Sbjct: 174 NRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALV 233
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
LE+I +NR++ VP + + +L+ LDL+KN I I+ G FS + +L+ L +++
Sbjct: 234 GLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINN 293
Query: 123 -NKINNISDNAFENXXXXXXXXXDRN-KLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
++ +I A +N N +L I F L L L L++N L +L
Sbjct: 294 MPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGT 353
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
ESL L+ + + N + DC + ++++K +RF+
Sbjct: 354 IESLPNLKEISIHSNPIR-------CDCV-IRWMNMNKTNIRFM 389
Score = 49.2 bits (112), Expect = 2e-04
Identities = 36/127 (28%), Positives = 64/127 (50%), Gaps = 3/127 (2%)
Query: 2 FDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSN-NYLYTLPEK 60
+DN + +P + +VNLK L L +N + I F++ L + ++N L ++
Sbjct: 244 YDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSL 303
Query: 61 LFANNTFLETIDISNN-RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQIL 118
N L I+ +NN R+ Y+ ++F L L+ L L+ N + + +GT SL NL+ +
Sbjct: 304 AVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEI 363
Query: 119 KLSDNKI 125
+ N I
Sbjct: 364 SIHSNPI 370
>AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple receptor
protein.
Length = 951
Score = 114 bits (274), Expect = 4e-24
Identities = 89/303 (29%), Positives = 133/303 (43%), Gaps = 8/303 (2%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ LP F++ L+ L+L N L I +A + K+L + L NN L T+P +
Sbjct: 67 NNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIR 126
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
+ L+++ + N + VP DSF GL L+ L L N + + S L LQ L L+
Sbjct: 127 GLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLAL 186
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
NKI++I D AF N NK++ + F+ L L LDLS NNL +
Sbjct: 187 NKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQA-IK 245
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
+ L+ L N++S IPD F L + L N L F+ +AF+
Sbjct: 246 ARPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRG 305
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN-----PWHCDC 297
+ F + +L +L L G S+P+ L + LS N P C
Sbjct: 306 ASMVQ-QFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGC 364
Query: 298 HAL 300
HAL
Sbjct: 365 HAL 367
Score = 98.7 bits (235), Expect = 2e-19
Identities = 82/306 (26%), Positives = 136/306 (44%), Gaps = 25/306 (8%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ +P FE LV L+ L L N L E+ ++ L + L+ N + ++P+ F
Sbjct: 139 NHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFT 198
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
N + L + + NN++ + F GL +L+ LDLS N + + +L+ L N
Sbjct: 199 NLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQAIKARPSLKELGFHSN 258
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLM----SLAG- 178
I+ I D AF+ N L + F+NL L L + +++ +L G
Sbjct: 259 SISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGT 318
Query: 179 VEFESL------------------KLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
V ESL K+LR LDL N + +P +F+ C LE++ L +N+
Sbjct: 319 VHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLP--SFNGCHALEEISLQRNQ 376
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ I F G +E+H +AF+ L +T L + N S P+ L+ +
Sbjct: 377 IYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGL 436
Query: 281 PKLTIV 286
+L +V
Sbjct: 437 NQLKLV 442
Score = 89.8 bits (213), Expect = 9e-17
Identities = 75/277 (27%), Positives = 117/277 (42%), Gaps = 6/277 (2%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
+ L + N + ++ +AF + L + L+ N L + K + L+ + + NN++
Sbjct: 60 QALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKT 119
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXX 139
VPS++ GL +LQ L L N I ++ +F L L+ L L DN + + + N
Sbjct: 120 VPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTL 179
Query: 140 XXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ 199
NK+ +IP F NL L+ L L NN + L+ F+ L L LDL N L +
Sbjct: 180 QALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGE 239
Query: 200 IPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNL 259
P +L++L N + I AF G V AF L +L
Sbjct: 240 FP-QAIKARPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDL 298
Query: 260 TTLYLDG----NMFPSLPSRTLDYMPKLTIVKLSGNP 292
+L + G FP+L LT K+S P
Sbjct: 299 HSLVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIP 335
Score = 89.0 bits (211), Expect = 2e-16
Identities = 69/247 (27%), Positives = 103/247 (41%), Gaps = 5/247 (2%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
VD S L +PE L A F + +DIS N + +P D+F L+ L L+ N + I
Sbjct: 41 VDCSGKGLTAVPEGLSA---FTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIH 97
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
S LK L++L L +N++ + A D N + ++P F L L
Sbjct: 98 PKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRH 157
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
L L +N+L + +L L+ L L N +S IPD F++ +L L L NK+R ++
Sbjct: 158 LWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLS 217
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
F G E +A +L L N +P D P L
Sbjct: 218 QHCFDGLDNLETLDLSYNNLGEFP-QAIKARPSLKELGFHSNSISVIPDGAFDGNPLLRT 276
Query: 286 VKLSGNP 292
+ L NP
Sbjct: 277 IHLYDNP 283
Score = 78.2 bits (184), Expect = 3e-13
Identities = 76/313 (24%), Positives = 129/313 (41%), Gaps = 27/313 (8%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ +P L L++LRL N++ + ++F +L H+ L +N L +P
Sbjct: 114 NNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPL 173
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
+N L+ + ++ N++ +P +F L SL +L L NKI+ + F L NL+ L LS
Sbjct: 174 SNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLS 233
Query: 122 -----------------------DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFN 158
N I+ I D AF+ N L + F+
Sbjct: 234 YNNLGEFPQAIKARPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFH 293
Query: 159 NLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSK 218
NL L L + +++ L +L L +S IP+N + L LDLS
Sbjct: 294 NLSDLHSLVIRGASMVQ-QFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSY 352
Query: 219 NKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLD 278
N +R ++ +F G Y++ F L +L L L N+ + SR
Sbjct: 353 NNIR--DLPSFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFA 410
Query: 279 YMPKLTIVKLSGN 291
+ +T + +S N
Sbjct: 411 TLGPITNLDVSFN 423
Score = 44.0 bits (99), Expect = 0.006
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 2/114 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ LP F L+ + LQRN + +I F L +DLS N ++ + + FA
Sbjct: 353 NNIRDLPS--FNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFA 410
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQI 117
+ +D+S N + P++ GL L+++ K K +L++L +
Sbjct: 411 TLGPITNLDVSFNELTSFPTEGLNGLNQLKLVGNFKLKEALAAKDFVNLRSLSV 464
>AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat
protein LRIG1 protein.
Length = 1093
Score = 113 bits (272), Expect = 6e-24
Identities = 80/284 (28%), Positives = 129/284 (45%), Gaps = 5/284 (1%)
Query: 10 PGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLE 69
P G FE L NL+ + L N L EID F L V L+NN L +P L A ++ +
Sbjct: 85 PAG-FEDLPNLQEVNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPS-LGAASSHVV 142
Query: 70 TIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSL-KNLQILKLSDNKINNI 128
++ + +N++ V SL++LDLS N I ++N F ++ L L+ N+I +
Sbjct: 143 SLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTL 202
Query: 129 SDNAFENXXXXXXXXX-DRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
AF+ +N++ +P + F L L LDL+ N + + G+ F+ L L
Sbjct: 203 ELGAFDGLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSL 261
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
L L+ N +S++ D F + L L N L +N + YG
Sbjct: 262 EVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIAR 321
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+H K +S + L L L N L +L + L++++LS N
Sbjct: 322 IHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHN 365
Score = 104 bits (249), Expect = 4e-21
Identities = 87/330 (26%), Positives = 149/330 (45%), Gaps = 7/330 (2%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + + G ++ ++L+ L L N + E+ + F + ++L+ N + TL F
Sbjct: 149 NKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFD 208
Query: 64 N-NTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
+ L T+ +S NR+ +P +F L L LDL++N+I+ I+ TF L +L++LKL
Sbjct: 209 GLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQ 267
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N I+ ++D AF + N L + + L L L LSNN++ + +
Sbjct: 268 RNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGW 327
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXX 241
+ L L L N L+++ + + ++ +L L LS N + I AF G
Sbjct: 328 SFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLD 387
Query: 242 X---XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCH 298
E AFS L +L+ L L GN S+ M L + +S + + CDC
Sbjct: 388 HNEISGTIEDTSGAFSGLDSLSKLNLGGNAIRSVQFDAFVKMKNLKELHISSDSFLCDCQ 447
Query: 299 ALYISAWVRLNEMKIWDYSPTCVSPWYLEG 328
++ W+ + M + TC P L+G
Sbjct: 448 LKWLPPWL-IGRMLQAFVTATCAHPESLKG 476
Score = 37.5 bits (83), Expect = 0.51
Identities = 21/56 (37%), Positives = 32/56 (57%)
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
L+LS N L + FE L L+ ++L N LS+I F D NL+++ L+ N+L
Sbjct: 73 LNLSYNKLSEIDPAGFEDLPNLQEVNLSYNKLSEIDPAGFEDLPNLQEVYLNNNEL 128
>AY250221-1|AAP82838.1| 420|Homo sapiens nogo receptor-like 3
protein.
Length = 420
Score = 113 bits (272), Expect = 6e-24
Identities = 79/246 (32%), Positives = 109/246 (44%), Gaps = 4/246 (1%)
Query: 91 SLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNK-L 149
S Q L L N I+ ++ TF NL L L N ++ I F + N+ L
Sbjct: 61 STQRLFLQNNLIRTLRPSTFG-SNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHL 119
Query: 150 KNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCF 209
+++ F L+ L L L L SL G F L L+ L L+EN+L + D+ F+D
Sbjct: 120 RSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLA 179
Query: 210 NLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
NL L L N+LR + F G VH AF L LT LYL N
Sbjct: 180 NLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSL 239
Query: 270 PSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGH 329
SLP L +P L ++L+ NPW CDC A + AW ++ TC +P +G
Sbjct: 240 ASLPGEALADLPSLEFLRLNANPWACDCRARPLWAW--FQRARVSSSDVTCATPPERQGR 297
Query: 330 FLKKLK 335
L+ L+
Sbjct: 298 DLRALR 303
Score = 59.7 bits (138), Expect = 1e-07
Identities = 39/116 (33%), Positives = 58/116 (50%), Gaps = 1/116 (0%)
Query: 9 LPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFL 68
LPG IF LV+L+ L LQ N L + + F L H+ L N L L E +F L
Sbjct: 146 LPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSL 205
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDN 123
+ + + NR+ V +F GL L IL L N + ++ + L +L+ L+L+ N
Sbjct: 206 DRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 54.0 bits (124), Expect = 6e-06
Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 1/131 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+ H+ L F+ L L++L L R L + F L ++ L N L L + LF
Sbjct: 116 NRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLF 175
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
A+ L + + NR+ + F GL SL L L N++Q + F L L IL L
Sbjct: 176 ADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLF 235
Query: 122 DNKINNISDNA 132
+N + ++ A
Sbjct: 236 NNSLASLPGEA 246
>CR457397-1|CAG33678.1| 708|Homo sapiens LRRN3 protein.
Length = 708
Score = 113 bits (271), Expect = 9e-24
Identities = 103/403 (25%), Positives = 176/403 (43%), Gaps = 22/403 (5%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNR 77
VNL L L +N L + + +L V L N L LPEK + + L+ + I++N
Sbjct: 92 VNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNL 151
Query: 78 VVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENX 136
+ + +F+GL++L L L+ N++Q I + F +L NL+IL + +N I I D F+
Sbjct: 152 LSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPL 211
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
L IP L+ L + +N L+ + V + + L+ LDL +N
Sbjct: 212 INLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNP 271
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF----YGXXXXXXXXXXXXXXYEVHFKA 252
+++I FS+ +L++L ++ N I+I + Y +H A
Sbjct: 272 INRIRRGDFSNMLHLKELGIN-NMPELISIDSLAVDNLPDLRKIEATNNPRLSY-IHPNA 329
Query: 253 FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMK 312
F L L +L L+ N +L T++ +P L + + NP CDC + W+ +N+
Sbjct: 330 FFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDC----VIRWMNMNKTN 385
Query: 313 IWDYSPT---CVSPWYLEGHFLKKLKF---PELCAGQWASMVNLSPRLPIQQLLALNVSV 366
I P CV P +G ++++ F E+C A + L ++ ++
Sbjct: 386 IRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPLIAP-ESFPSNLNVEAGSYVSFHC 444
Query: 367 N-RCQMDGVIMWPIPVSESILD---THTGYVLDRGTTDIEDIT 405
+ I W P + +L T YV GT DI +T
Sbjct: 445 RATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVT 487
Score = 60.5 bits (140), Expect = 6e-08
Identities = 56/224 (25%), Positives = 104/224 (46%), Gaps = 11/224 (4%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ + F++L NL+ L + N + I F L + ++ L +P+
Sbjct: 174 NRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALV 233
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
LE+I +NR++ VP + + +L+ LDL+KN I I+ G FS + +L+ L +++
Sbjct: 234 GLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINN 293
Query: 123 -NKINNISDNAFENXXXXXXXXXDRN-KLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
++ +I A +N N +L I F L L L L++N L +L
Sbjct: 294 MPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGT 353
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
ESL L+ + + N + DC + ++++K +RF+
Sbjct: 354 IESLPNLKEISIHSNPIR-------CDCV-IRWMNMNKTNIRFM 389
Score = 49.2 bits (112), Expect = 2e-04
Identities = 36/127 (28%), Positives = 64/127 (50%), Gaps = 3/127 (2%)
Query: 2 FDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSN-NYLYTLPEK 60
+DN + +P + +VNLK L L +N + I F++ L + ++N L ++
Sbjct: 244 YDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSL 303
Query: 61 LFANNTFLETIDISNN-RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQIL 118
N L I+ +NN R+ Y+ ++F L L+ L L+ N + + +GT SL NL+ +
Sbjct: 304 AVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEI 363
Query: 119 KLSDNKI 125
+ N I
Sbjct: 364 SIHSNPI 370
>AY358280-1|AAQ88647.1| 708|Homo sapiens LRRN3 protein.
Length = 708
Score = 113 bits (271), Expect = 9e-24
Identities = 103/403 (25%), Positives = 176/403 (43%), Gaps = 22/403 (5%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNR 77
VNL L L +N L + + +L V L N L LPEK + + L+ + I++N
Sbjct: 92 VNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNL 151
Query: 78 VVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENX 136
+ + +F+GL++L L L+ N++Q I + F +L NL+IL + +N I I D F+
Sbjct: 152 LSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPL 211
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
L IP L+ L + +N L+ + V + + L+ LDL +N
Sbjct: 212 INLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNP 271
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF----YGXXXXXXXXXXXXXXYEVHFKA 252
+++I FS+ +L++L ++ N I+I + Y +H A
Sbjct: 272 INRIRRGDFSNMLHLKELGIN-NMPELISIDSLAVDNLPDLRKIEATNNPRLSY-IHPNA 329
Query: 253 FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMK 312
F L L +L L+ N +L T++ +P L + + NP CDC + W+ +N+
Sbjct: 330 FFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDC----VIRWMNMNKTN 385
Query: 313 IWDYSPT---CVSPWYLEGHFLKKLKF---PELCAGQWASMVNLSPRLPIQQLLALNVSV 366
I P CV P +G ++++ F E+C A + L ++ ++
Sbjct: 386 IRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPLIAP-ESFPSNLNVEAGSYVSFHC 444
Query: 367 N-RCQMDGVIMWPIPVSESILD---THTGYVLDRGTTDIEDIT 405
+ I W P + +L T YV GT DI +T
Sbjct: 445 RATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVT 487
Score = 60.5 bits (140), Expect = 6e-08
Identities = 56/224 (25%), Positives = 104/224 (46%), Gaps = 11/224 (4%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ + F++L NL+ L + N + I F L + ++ L +P+
Sbjct: 174 NRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALV 233
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
LE+I +NR++ VP + + +L+ LDL+KN I I+ G FS + +L+ L +++
Sbjct: 234 GLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINN 293
Query: 123 -NKINNISDNAFENXXXXXXXXXDRN-KLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
++ +I A +N N +L I F L L L L++N L +L
Sbjct: 294 MPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGT 353
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
ESL L+ + + N + DC + ++++K +RF+
Sbjct: 354 IESLPNLKEISIHSNPIR-------CDCV-IRWMNMNKTNIRFM 389
Score = 49.2 bits (112), Expect = 2e-04
Identities = 36/127 (28%), Positives = 64/127 (50%), Gaps = 3/127 (2%)
Query: 2 FDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSN-NYLYTLPEK 60
+DN + +P + +VNLK L L +N + I F++ L + ++N L ++
Sbjct: 244 YDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSL 303
Query: 61 LFANNTFLETIDISNN-RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQIL 118
N L I+ +NN R+ Y+ ++F L L+ L L+ N + + +GT SL NL+ +
Sbjct: 304 AVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEI 363
Query: 119 KLSDNKI 125
+ N I
Sbjct: 364 SIHSNPI 370
>AF134481-1|AAP97258.1| 708|Homo sapiens leucine-rich repeat
protein protein.
Length = 708
Score = 113 bits (271), Expect = 9e-24
Identities = 103/403 (25%), Positives = 176/403 (43%), Gaps = 22/403 (5%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNR 77
VNL L L +N L + + +L V L N L LPEK + + L+ + I++N
Sbjct: 92 VNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNL 151
Query: 78 VVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENX 136
+ + +F+GL++L L L+ N++Q I + F +L NL+IL + +N I I D F+
Sbjct: 152 LSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPL 211
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
L IP L+ L + +N L+ + V + + L+ LDL +N
Sbjct: 212 INLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNP 271
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF----YGXXXXXXXXXXXXXXYEVHFKA 252
+++I FS+ +L++L ++ N I+I + Y +H A
Sbjct: 272 INRIRRGDFSNMLHLKELGIN-NMPELISIDSLAVDNLPDLRKIEATNNPRLSY-IHPNA 329
Query: 253 FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMK 312
F L L +L L+ N +L T++ +P L + + NP CDC + W+ +N+
Sbjct: 330 FFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDC----VIRWMNMNKTN 385
Query: 313 IWDYSPT---CVSPWYLEGHFLKKLKF---PELCAGQWASMVNLSPRLPIQQLLALNVSV 366
I P CV P +G ++++ F E+C A + L ++ ++
Sbjct: 386 IRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPLIAP-ESFPSNLNVEAGSYVSFHC 444
Query: 367 N-RCQMDGVIMWPIPVSESILD---THTGYVLDRGTTDIEDIT 405
+ I W P + +L T YV GT DI +T
Sbjct: 445 RATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVT 487
Score = 60.5 bits (140), Expect = 6e-08
Identities = 56/224 (25%), Positives = 104/224 (46%), Gaps = 11/224 (4%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ + F++L NL+ L + N + I F L + ++ L +P+
Sbjct: 174 NRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALV 233
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
LE+I +NR++ VP + + +L+ LDL+KN I I+ G FS + +L+ L +++
Sbjct: 234 GLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINN 293
Query: 123 -NKINNISDNAFENXXXXXXXXXDRN-KLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
++ +I A +N N +L I F L L L L++N L +L
Sbjct: 294 MPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGT 353
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
ESL L+ + + N + DC + ++++K +RF+
Sbjct: 354 IESLPNLKEISIHSNPIR-------CDCV-IRWMNMNKTNIRFM 389
Score = 49.2 bits (112), Expect = 2e-04
Identities = 36/127 (28%), Positives = 64/127 (50%), Gaps = 3/127 (2%)
Query: 2 FDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSN-NYLYTLPEK 60
+DN + +P + +VNLK L L +N + I F++ L + ++N L ++
Sbjct: 244 YDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSL 303
Query: 61 LFANNTFLETIDISNN-RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQIL 118
N L I+ +NN R+ Y+ ++F L L+ L L+ N + + +GT SL NL+ +
Sbjct: 304 AVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEI 363
Query: 119 KLSDNKI 125
+ N I
Sbjct: 364 SIHSNPI 370
>AB060967-1|BAB47184.1| 708|Homo sapiens neuronal leucine-rich
repeat protein-3 protein.
Length = 708
Score = 113 bits (271), Expect = 9e-24
Identities = 103/403 (25%), Positives = 176/403 (43%), Gaps = 22/403 (5%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNR 77
VNL L L +N L + + +L V L N L LPEK + + L+ + I++N
Sbjct: 92 VNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNL 151
Query: 78 VVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENX 136
+ + +F+GL++L L L+ N++Q I + F +L NL+IL + +N I I D F+
Sbjct: 152 LSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPL 211
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
L IP L+ L + +N L+ + V + + L+ LDL +N
Sbjct: 212 INLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNP 271
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF----YGXXXXXXXXXXXXXXYEVHFKA 252
+++I FS+ +L++L ++ N I+I + Y +H A
Sbjct: 272 INRIRRGDFSNMLHLKELGIN-NMPELISIDSLAVDNLPDLRKIEATNNPRLSY-IHPNA 329
Query: 253 FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMK 312
F L L +L L+ N +L T++ +P L + + NP CDC + W+ +N+
Sbjct: 330 FFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDC----VIRWMNMNKTN 385
Query: 313 IWDYSPT---CVSPWYLEGHFLKKLKF---PELCAGQWASMVNLSPRLPIQQLLALNVSV 366
I P CV P +G ++++ F E+C A + L ++ ++
Sbjct: 386 IRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPLIAP-ESFPSNLNVEAGSYVSFHC 444
Query: 367 N-RCQMDGVIMWPIPVSESILD---THTGYVLDRGTTDIEDIT 405
+ I W P + +L T YV GT DI +T
Sbjct: 445 RATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVT 487
Score = 60.5 bits (140), Expect = 6e-08
Identities = 56/224 (25%), Positives = 104/224 (46%), Gaps = 11/224 (4%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ + F++L NL+ L + N + I F L + ++ L +P+
Sbjct: 174 NRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALV 233
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
LE+I +NR++ VP + + +L+ LDL+KN I I+ G FS + +L+ L +++
Sbjct: 234 GLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINN 293
Query: 123 -NKINNISDNAFENXXXXXXXXXDRN-KLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
++ +I A +N N +L I F L L L L++N L +L
Sbjct: 294 MPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGT 353
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
ESL L+ + + N + DC + ++++K +RF+
Sbjct: 354 IESLPNLKEISIHSNPIR-------CDCV-IRWMNMNKTNIRFM 389
Score = 49.2 bits (112), Expect = 2e-04
Identities = 36/127 (28%), Positives = 64/127 (50%), Gaps = 3/127 (2%)
Query: 2 FDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSN-NYLYTLPEK 60
+DN + +P + +VNLK L L +N + I F++ L + ++N L ++
Sbjct: 244 YDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSL 303
Query: 61 LFANNTFLETIDISNN-RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQIL 118
N L I+ +NN R+ Y+ ++F L L+ L L+ N + + +GT SL NL+ +
Sbjct: 304 AVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEI 363
Query: 119 KLSDNKI 125
+ N I
Sbjct: 364 SIHSNPI 370
>DQ084201-1|AAY86708.1| 640|Homo sapiens netrin-G1 ligand splice
variant 3 protein.
Length = 640
Score = 112 bits (269), Expect = 1e-23
Identities = 80/272 (29%), Positives = 127/272 (46%), Gaps = 4/272 (1%)
Query: 65 NTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDN 123
+T +++ N++ + +SF L L+IL LS+N I+ I+ G F+ L NL L+L DN
Sbjct: 75 STNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDN 134
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMS-LAGVEFE 182
++ IS+ AF N +++IP+ FN + L LDL +S ++ FE
Sbjct: 135 RLTTISNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFE 194
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L LR L+L L +IP+ T L++LDLS N L I +F G
Sbjct: 195 GLSNLRYLNLAMCNLREIPNLT--PLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQ 252
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYI 302
+ AF L++L + L N LP + L + L NPW C+C L++
Sbjct: 253 SQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWSCNCDILWL 312
Query: 303 SAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKL 334
S W++ C +P L+G ++ +L
Sbjct: 313 SWWIKDMAPSNTACCARCNTPPNLKGRYIGEL 344
Score = 71.3 bits (167), Expect = 3e-11
Identities = 56/221 (25%), Positives = 104/221 (47%), Gaps = 4/221 (1%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N ++ + F+ L +L+ L+L RN++ I+ AF L ++L +N L T+
Sbjct: 83 LHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTISNG 142
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSK-NKIQNIQNGTF-SLKNLQIL 118
F + L+ + + NN + +PS +F + SL+ LDL + ++ I G F L NL+ L
Sbjct: 143 AFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYL 202
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
L+ + I + N L I F L L L + + + +
Sbjct: 203 NLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIER 260
Query: 179 VEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
F++L+ L ++L N L+ +P + F+ +LE++ L N
Sbjct: 261 NAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
>BC110058-1|AAI10059.1| 518|Homo sapiens leucine rich repeat
transmembrane neuronal 4 protein.
Length = 518
Score = 111 bits (267), Expect = 3e-23
Identities = 80/283 (28%), Positives = 123/283 (43%), Gaps = 2/283 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N + L FA L + + +N + V D+F G+ L+ L LS NKI +
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
N TF + NL+ L LS NK+ + F+ N LK +P ++F + + L F
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
LDL N L SL+ F L L+ L L+ N S+I F FNL + L N++R I+
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
+ + F L NL L LD N ++ T++ L
Sbjct: 246 QGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLIS 305
Query: 286 VKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG 328
+ LSGN W C + W++ N + + C P +++G
Sbjct: 306 ITLSGNMWECSRSICPLFYWLK-NFKGNKESTMICAGPKHIQG 347
Score = 97.1 bits (231), Expect = 6e-19
Identities = 68/223 (30%), Positives = 103/223 (46%), Gaps = 1/223 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ L F L L L L NY+ +D +AF ++L + LS+N + L K F
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+S N++ + S+ F GL L IL L N ++ + F +NL L L
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N++ ++S NAF + N+ I F L L + L N + S++
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
+ L NLDL N + I TF NL+KL+L NKL I+
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNIS 293
Score = 93.1 bits (221), Expect = 1e-17
Identities = 66/223 (29%), Positives = 104/223 (46%), Gaps = 6/223 (2%)
Query: 75 NNRVVYVPSDSFLGLYS-----LQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNI 128
+ ++VY S +F + Q L L N IQ +++ F+ L L L L N I+++
Sbjct: 41 DGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSV 100
Query: 129 SDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLR 188
++AF+ NK+ + + F+ + L LDLS N L +L +F+ L+ L
Sbjct: 101 DEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLI 160
Query: 189 NLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEV 248
L L+ N+L +P F DC NL+ LDL N+LR ++ AF G ++
Sbjct: 161 ILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKI 220
Query: 249 HFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+F F L NL ++YL N S+ L + LSGN
Sbjct: 221 NFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGN 263
Score = 45.6 bits (103), Expect = 0.002
Identities = 30/106 (28%), Positives = 49/106 (46%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L F L+ LK L L+ N +I+ F L + L N + ++ + L
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT 109
+ L +D+S N + + +F L +LQ L+L NK+ NI T
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQET 296
Score = 33.5 bits (73), Expect = 8.3
Identities = 21/87 (24%), Positives = 41/87 (47%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F L NL+++ LQ N + I + L ++DLS N + + F L+ +++
Sbjct: 225 FPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNL 284
Query: 74 SNNRVVYVPSDSFLGLYSLQILDLSKN 100
+N++ + ++ SL + LS N
Sbjct: 285 DSNKLTNISQETVNAWISLISITLSGN 311
>BC099738-1|AAH99738.1| 518|Homo sapiens leucine rich repeat
transmembrane neuronal 4 protein.
Length = 518
Score = 111 bits (267), Expect = 3e-23
Identities = 80/283 (28%), Positives = 123/283 (43%), Gaps = 2/283 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N + L FA L + + +N + V D+F G+ L+ L LS NKI +
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
N TF + NL+ L LS NK+ + F+ N LK +P ++F + + L F
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
LDL N L SL+ F L L+ L L+ N S+I F FNL + L N++R I+
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
+ + F L NL L LD N ++ T++ L
Sbjct: 246 QGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLIS 305
Query: 286 VKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG 328
+ LSGN W C + W++ N + + C P +++G
Sbjct: 306 ITLSGNMWECSRSICPLFYWLK-NFKGNKESTMICAGPKHIQG 347
Score = 97.1 bits (231), Expect = 6e-19
Identities = 68/223 (30%), Positives = 103/223 (46%), Gaps = 1/223 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ L F L L L L NY+ +D +AF ++L + LS+N + L K F
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+S N++ + S+ F GL L IL L N ++ + F +NL L L
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N++ ++S NAF + N+ I F L L + L N + S++
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
+ L NLDL N + I TF NL+KL+L NKL I+
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNIS 293
Score = 93.1 bits (221), Expect = 1e-17
Identities = 66/223 (29%), Positives = 104/223 (46%), Gaps = 6/223 (2%)
Query: 75 NNRVVYVPSDSFLGLYS-----LQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNI 128
+ ++VY S +F + Q L L N IQ +++ F+ L L L L N I+++
Sbjct: 41 DGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSV 100
Query: 129 SDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLR 188
++AF+ NK+ + + F+ + L LDLS N L +L +F+ L+ L
Sbjct: 101 DEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLI 160
Query: 189 NLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEV 248
L L+ N+L +P F DC NL+ LDL N+LR ++ AF G ++
Sbjct: 161 ILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKI 220
Query: 249 HFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+F F L NL ++YL N S+ L + LSGN
Sbjct: 221 NFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGN 263
Score = 45.6 bits (103), Expect = 0.002
Identities = 30/106 (28%), Positives = 49/106 (46%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L F L+ LK L L+ N +I+ F L + L N + ++ + L
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT 109
+ L +D+S N + + +F L +LQ L+L NK+ NI T
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQET 296
Score = 33.5 bits (73), Expect = 8.3
Identities = 21/87 (24%), Positives = 41/87 (47%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F L NL+++ LQ N + I + L ++DLS N + + F L+ +++
Sbjct: 225 FPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNL 284
Query: 74 SNNRVVYVPSDSFLGLYSLQILDLSKN 100
+N++ + ++ SL + LS N
Sbjct: 285 DSNKLTNISQETVNAWISLISITLSGN 311
>BC098301-1|AAH98301.1| 519|Homo sapiens LRRTM4 protein protein.
Length = 519
Score = 111 bits (267), Expect = 3e-23
Identities = 80/283 (28%), Positives = 123/283 (43%), Gaps = 2/283 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N + L FA L + + +N + V D+F G+ L+ L LS NKI +
Sbjct: 67 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 126
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
N TF + NL+ L LS NK+ + F+ N LK +P ++F + + L F
Sbjct: 127 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 186
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
LDL N L SL+ F L L+ L L+ N S+I F FNL + L N++R I+
Sbjct: 187 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 246
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
+ + F L NL L LD N ++ T++ L
Sbjct: 247 QGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLIS 306
Query: 286 VKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG 328
+ LSGN W C + W++ N + + C P +++G
Sbjct: 307 ITLSGNMWECSRSICPLFYWLK-NFKGNKESTMICAGPKHIQG 348
Score = 97.1 bits (231), Expect = 6e-19
Identities = 68/223 (30%), Positives = 103/223 (46%), Gaps = 1/223 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ L F L L L L NY+ +D +AF ++L + LS+N + L K F
Sbjct: 72 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 131
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+S N++ + S+ F GL L IL L N ++ + F +NL L L
Sbjct: 132 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 191
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N++ ++S NAF + N+ I F L L + L N + S++
Sbjct: 192 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 251
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
+ L NLDL N + I TF NL+KL+L NKL I+
Sbjct: 252 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNIS 294
Score = 93.1 bits (221), Expect = 1e-17
Identities = 66/223 (29%), Positives = 104/223 (46%), Gaps = 6/223 (2%)
Query: 75 NNRVVYVPSDSFLGLYS-----LQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNI 128
+ ++VY S +F + Q L L N IQ +++ F+ L L L L N I+++
Sbjct: 42 DGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSV 101
Query: 129 SDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLR 188
++AF+ NK+ + + F+ + L LDLS N L +L +F+ L+ L
Sbjct: 102 DEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLI 161
Query: 189 NLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEV 248
L L+ N+L +P F DC NL+ LDL N+LR ++ AF G ++
Sbjct: 162 ILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKI 221
Query: 249 HFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+F F L NL ++YL N S+ L + LSGN
Sbjct: 222 NFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGN 264
Score = 45.6 bits (103), Expect = 0.002
Identities = 30/106 (28%), Positives = 49/106 (46%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L F L+ LK L L+ N +I+ F L + L N + ++ + L
Sbjct: 192 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 251
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT 109
+ L +D+S N + + +F L +LQ L+L NK+ NI T
Sbjct: 252 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQET 297
Score = 33.5 bits (73), Expect = 8.3
Identities = 21/87 (24%), Positives = 41/87 (47%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F L NL+++ LQ N + I + L ++DLS N + + F L+ +++
Sbjct: 226 FPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNL 285
Query: 74 SNNRVVYVPSDSFLGLYSLQILDLSKN 100
+N++ + ++ SL + LS N
Sbjct: 286 DSNKLTNISQETVNAWISLISITLSGN 312
>BC098267-1|AAH98267.1| 519|Homo sapiens LRRTM4 protein protein.
Length = 519
Score = 111 bits (267), Expect = 3e-23
Identities = 80/283 (28%), Positives = 123/283 (43%), Gaps = 2/283 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N + L FA L + + +N + V D+F G+ L+ L LS NKI +
Sbjct: 67 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 126
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
N TF + NL+ L LS NK+ + F+ N LK +P ++F + + L F
Sbjct: 127 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 186
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
LDL N L SL+ F L L+ L L+ N S+I F FNL + L N++R I+
Sbjct: 187 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 246
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
+ + F L NL L LD N ++ T++ L
Sbjct: 247 QGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLIS 306
Query: 286 VKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG 328
+ LSGN W C + W++ N + + C P +++G
Sbjct: 307 ITLSGNMWECSRSICPLFYWLK-NFKGNKESTMICAGPKHIQG 348
Score = 97.1 bits (231), Expect = 6e-19
Identities = 68/223 (30%), Positives = 103/223 (46%), Gaps = 1/223 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ L F L L L L NY+ +D +AF ++L + LS+N + L K F
Sbjct: 72 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 131
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+S N++ + S+ F GL L IL L N ++ + F +NL L L
Sbjct: 132 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 191
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N++ ++S NAF + N+ I F L L + L N + S++
Sbjct: 192 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 251
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
+ L NLDL N + I TF NL+KL+L NKL I+
Sbjct: 252 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNIS 294
Score = 93.1 bits (221), Expect = 1e-17
Identities = 66/223 (29%), Positives = 104/223 (46%), Gaps = 6/223 (2%)
Query: 75 NNRVVYVPSDSFLGLYS-----LQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNI 128
+ ++VY S +F + Q L L N IQ +++ F+ L L L L N I+++
Sbjct: 42 DGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSV 101
Query: 129 SDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLR 188
++AF+ NK+ + + F+ + L LDLS N L +L +F+ L+ L
Sbjct: 102 DEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLI 161
Query: 189 NLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEV 248
L L+ N+L +P F DC NL+ LDL N+LR ++ AF G ++
Sbjct: 162 ILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKI 221
Query: 249 HFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+F F L NL ++YL N S+ L + LSGN
Sbjct: 222 NFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGN 264
Score = 45.6 bits (103), Expect = 0.002
Identities = 30/106 (28%), Positives = 49/106 (46%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L F L+ LK L L+ N +I+ F L + L N + ++ + L
Sbjct: 192 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 251
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT 109
+ L +D+S N + + +F L +LQ L+L NK+ NI T
Sbjct: 252 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQET 297
Score = 33.5 bits (73), Expect = 8.3
Identities = 21/87 (24%), Positives = 41/87 (47%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F L NL+++ LQ N + I + L ++DLS N + + F L+ +++
Sbjct: 226 FPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNL 285
Query: 74 SNNRVVYVPSDSFLGLYSLQILDLSKN 100
+N++ + ++ SL + LS N
Sbjct: 286 DSNKLTNISQETVNAWISLISITLSGN 312
>AY358324-1|AAQ88690.1| 590|Homo sapiens GFHL3075 protein.
Length = 590
Score = 111 bits (267), Expect = 3e-23
Identities = 80/283 (28%), Positives = 123/283 (43%), Gaps = 2/283 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N + L FA L + + +N + V D+F G+ L+ L LS NKI +
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
N TF + NL+ L LS NK+ + F+ N LK +P ++F + + L F
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
LDL N L SL+ F L L+ L L+ N S+I F FNL + L N++R I+
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
+ + F L NL L LD N ++ T++ L
Sbjct: 246 QGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLIS 305
Query: 286 VKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG 328
+ LSGN W C + W++ N + + C P +++G
Sbjct: 306 ITLSGNMWECSRSICPLFYWLK-NFKGNKESTMICAGPKHIQG 347
Score = 97.1 bits (231), Expect = 6e-19
Identities = 68/223 (30%), Positives = 103/223 (46%), Gaps = 1/223 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ L F L L L L NY+ +D +AF ++L + LS+N + L K F
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+S N++ + S+ F GL L IL L N ++ + F +NL L L
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N++ ++S NAF + N+ I F L L + L N + S++
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
+ L NLDL N + I TF NL+KL+L NKL I+
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNIS 293
Score = 93.1 bits (221), Expect = 1e-17
Identities = 66/223 (29%), Positives = 104/223 (46%), Gaps = 6/223 (2%)
Query: 75 NNRVVYVPSDSFLGLYS-----LQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNI 128
+ ++VY S +F + Q L L N IQ +++ F+ L L L L N I+++
Sbjct: 41 DGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSV 100
Query: 129 SDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLR 188
++AF+ NK+ + + F+ + L LDLS N L +L +F+ L+ L
Sbjct: 101 DEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLI 160
Query: 189 NLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEV 248
L L+ N+L +P F DC NL+ LDL N+LR ++ AF G ++
Sbjct: 161 ILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKI 220
Query: 249 HFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+F F L NL ++YL N S+ L + LSGN
Sbjct: 221 NFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGN 263
Score = 45.6 bits (103), Expect = 0.002
Identities = 30/106 (28%), Positives = 49/106 (46%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L F L+ LK L L+ N +I+ F L + L N + ++ + L
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT 109
+ L +D+S N + + +F L +LQ L+L NK+ NI T
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQET 296
Score = 33.5 bits (73), Expect = 8.3
Identities = 21/87 (24%), Positives = 41/87 (47%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F L NL+++ LQ N + I + L ++DLS N + + F L+ +++
Sbjct: 225 FPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNL 284
Query: 74 SNNRVVYVPSDSFLGLYSLQILDLSKN 100
+N++ + ++ SL + LS N
Sbjct: 285 DSNKLTNISQETVNAWISLISITLSGN 311
>AY182030-1|AAO67551.1| 518|Homo sapiens leucine-rich repeat
transmembrane neuronal 4 protein protein.
Length = 518
Score = 111 bits (267), Expect = 3e-23
Identities = 80/283 (28%), Positives = 123/283 (43%), Gaps = 2/283 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N + L FA L + + +N + V D+F G+ L+ L LS NKI +
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
N TF + NL+ L LS NK+ + F+ N LK +P ++F + + L F
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
LDL N L SL+ F L L+ L L+ N S+I F FNL + L N++R I+
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
+ + F L NL L LD N ++ T++ L
Sbjct: 246 QGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLIS 305
Query: 286 VKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG 328
+ LSGN W C + W++ N + + C P +++G
Sbjct: 306 ITLSGNMWECSRSICPLFYWLK-NFKGNKESTMICAGPKHIQG 347
Score = 97.1 bits (231), Expect = 6e-19
Identities = 68/223 (30%), Positives = 103/223 (46%), Gaps = 1/223 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ L F L L L L NY+ +D +AF ++L + LS+N + L K F
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+S N++ + S+ F GL L IL L N ++ + F +NL L L
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N++ ++S NAF + N+ I F L L + L N + S++
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
+ L NLDL N + I TF NL+KL+L NKL I+
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNIS 293
Score = 93.1 bits (221), Expect = 1e-17
Identities = 66/223 (29%), Positives = 104/223 (46%), Gaps = 6/223 (2%)
Query: 75 NNRVVYVPSDSFLGLYS-----LQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNI 128
+ ++VY S +F + Q L L N IQ +++ F+ L L L L N I+++
Sbjct: 41 DGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSV 100
Query: 129 SDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLR 188
++AF+ NK+ + + F+ + L LDLS N L +L +F+ L+ L
Sbjct: 101 DEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLI 160
Query: 189 NLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEV 248
L L+ N+L +P F DC NL+ LDL N+LR ++ AF G ++
Sbjct: 161 ILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKI 220
Query: 249 HFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+F F L NL ++YL N S+ L + LSGN
Sbjct: 221 NFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGN 263
Score = 45.6 bits (103), Expect = 0.002
Identities = 30/106 (28%), Positives = 49/106 (46%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L F L+ LK L L+ N +I+ F L + L N + ++ + L
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT 109
+ L +D+S N + + +F L +LQ L+L NK+ NI T
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQET 296
Score = 33.5 bits (73), Expect = 8.3
Identities = 21/87 (24%), Positives = 41/87 (47%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F L NL+++ LQ N + I + L ++DLS N + + F L+ +++
Sbjct: 225 FPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNL 284
Query: 74 SNNRVVYVPSDSFLGLYSLQILDLSKN 100
+N++ + ++ SL + LS N
Sbjct: 285 DSNKLTNISQETVNAWISLISITLSGN 311
>AK126961-1|BAC86764.1| 518|Homo sapiens protein ( Homo sapiens
cDNA FLJ45014 fis, clone BRAWH3014609. ).
Length = 518
Score = 111 bits (267), Expect = 3e-23
Identities = 80/283 (28%), Positives = 123/283 (43%), Gaps = 2/283 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N + L FA L + + +N + V D+F G+ L+ L LS NKI +
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
N TF + NL+ L LS NK+ + F+ N LK +P ++F + + L F
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
LDL N L SL+ F L L+ L L+ N S+I F FNL + L N++R I+
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
+ + F L NL L LD N ++ T++ L
Sbjct: 246 QGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLIS 305
Query: 286 VKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG 328
+ LSGN W C + W++ N + + C P +++G
Sbjct: 306 ITLSGNMWECSRSICPLFYWLK-NFKGNKESTMICAGPKHIQG 347
Score = 97.1 bits (231), Expect = 6e-19
Identities = 68/223 (30%), Positives = 103/223 (46%), Gaps = 1/223 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ L F L L L L NY+ +D +AF ++L + LS+N + L K F
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+S N++ + S+ F GL L IL L N ++ + F +NL L L
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N++ ++S NAF + N+ I F L L + L N + S++
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
+ L NLDL N + I TF NL+KL+L NKL I+
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNIS 293
Score = 95.9 bits (228), Expect = 1e-18
Identities = 67/223 (30%), Positives = 105/223 (47%), Gaps = 6/223 (2%)
Query: 75 NNRVVYVPSDSFLGLYS-----LQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNI 128
+ ++VY S +F G+ Q L L N IQ +++ F+ L L L L N I+++
Sbjct: 41 DGKIVYCESHAFAGIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSV 100
Query: 129 SDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLR 188
++AF+ NK+ + + F+ + L LDLS N L +L +F+ L+ L
Sbjct: 101 DEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLI 160
Query: 189 NLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEV 248
L L+ N+L +P F DC NL+ LDL N+LR ++ AF G ++
Sbjct: 161 ILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKI 220
Query: 249 HFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+F F L NL ++YL N S+ L + LSGN
Sbjct: 221 NFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGN 263
Score = 45.6 bits (103), Expect = 0.002
Identities = 30/106 (28%), Positives = 49/106 (46%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L F L+ LK L L+ N +I+ F L + L N + ++ + L
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT 109
+ L +D+S N + + +F L +LQ L+L NK+ NI T
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQET 296
Score = 33.5 bits (73), Expect = 8.3
Identities = 21/87 (24%), Positives = 41/87 (47%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F L NL+++ LQ N + I + L ++DLS N + + F L+ +++
Sbjct: 225 FPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNL 284
Query: 74 SNNRVVYVPSDSFLGLYSLQILDLSKN 100
+N++ + ++ SL + LS N
Sbjct: 285 DSNKLTNISQETVNAWISLISITLSGN 311
>BC041374-1|AAH41374.3| 640|Homo sapiens LRRC4C protein protein.
Length = 640
Score = 111 bits (266), Expect = 3e-23
Identities = 79/272 (29%), Positives = 127/272 (46%), Gaps = 4/272 (1%)
Query: 65 NTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDN 123
+T +++ N++ + +SF L L+IL LS+N I+ I+ G F+ L NL L+L DN
Sbjct: 75 STNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDN 134
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMS-LAGVEFE 182
++ I + AF N +++IP+ FN + L LDL +S ++ FE
Sbjct: 135 RLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFE 194
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L LR L+L L +IP+ T L++LDLS N L I +F G
Sbjct: 195 GLSNLRYLNLAMCNLREIPNLT--PLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQ 252
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYI 302
+ AF L++L + L N LP + L + L NPW+C+C L++
Sbjct: 253 SQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWL 312
Query: 303 SAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKL 334
S W++ C +P L+G ++ +L
Sbjct: 313 SWWIKDMAPSNTACCARCNTPPNLKGRYIGEL 344
Score = 76.2 bits (179), Expect = 1e-12
Identities = 56/208 (26%), Positives = 104/208 (50%), Gaps = 4/208 (1%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L N ++ I +F + L + LS N++ T+ F L T+++ +NR+
Sbjct: 77 NTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRL 136
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD-NKINNISDNAFENX 136
+P+ +F+ L L+ L L N I++I + F+ + +L+ L L + +++ IS+ AFE
Sbjct: 137 TTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGL 196
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
L+ IP L L LDLS N+L ++ F+ L L+ L + ++
Sbjct: 197 SNLRYLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQ 254
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ I N F + +L +++L+ N L +
Sbjct: 255 IQVIERNAFDNLQSLVEINLAHNNLTLL 282
Score = 74.5 bits (175), Expect = 4e-12
Identities = 57/221 (25%), Positives = 105/221 (47%), Gaps = 4/221 (1%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N ++ + F+ L +L+ L+L RN++ I+ AF L ++L +N L T+P
Sbjct: 83 LHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNG 142
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSK-NKIQNIQNGTF-SLKNLQIL 118
F + L+ + + NN + +PS +F + SL+ LDL + ++ I G F L NL+ L
Sbjct: 143 AFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYL 202
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
L+ + I + N L I F L L L + + + +
Sbjct: 203 NLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIER 260
Query: 179 VEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
F++L+ L ++L N L+ +P + F+ +LE++ L N
Sbjct: 261 NAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
>AY358293-1|AAQ88660.1| 640|Homo sapiens LNKM292 protein.
Length = 640
Score = 111 bits (266), Expect = 3e-23
Identities = 79/272 (29%), Positives = 127/272 (46%), Gaps = 4/272 (1%)
Query: 65 NTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDN 123
+T +++ N++ + +SF L L+IL LS+N I+ I+ G F+ L NL L+L DN
Sbjct: 75 STNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDN 134
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMS-LAGVEFE 182
++ I + AF N +++IP+ FN + L LDL +S ++ FE
Sbjct: 135 RLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFE 194
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L LR L+L L +IP+ T L++LDLS N L I +F G
Sbjct: 195 GLSNLRYLNLAMCNLREIPNLT--PLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQ 252
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYI 302
+ AF L++L + L N LP + L + L NPW+C+C L++
Sbjct: 253 SQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWL 312
Query: 303 SAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKL 334
S W++ C +P L+G ++ +L
Sbjct: 313 SWWIKDMAPSNTACCARCNTPPNLKGRYIGEL 344
Score = 76.2 bits (179), Expect = 1e-12
Identities = 56/208 (26%), Positives = 104/208 (50%), Gaps = 4/208 (1%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L N ++ I +F + L + LS N++ T+ F L T+++ +NR+
Sbjct: 77 NTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRL 136
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD-NKINNISDNAFENX 136
+P+ +F+ L L+ L L N I++I + F+ + +L+ L L + +++ IS+ AFE
Sbjct: 137 TTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGL 196
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
L+ IP L L LDLS N+L ++ F+ L L+ L + ++
Sbjct: 197 SNLRYLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQ 254
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ I N F + +L +++L+ N L +
Sbjct: 255 IQVIERNAFDNLQSLVEINLAHNNLTLL 282
Score = 74.5 bits (175), Expect = 4e-12
Identities = 57/221 (25%), Positives = 105/221 (47%), Gaps = 4/221 (1%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N ++ + F+ L +L+ L+L RN++ I+ AF L ++L +N L T+P
Sbjct: 83 LHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNG 142
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSK-NKIQNIQNGTF-SLKNLQIL 118
F + L+ + + NN + +PS +F + SL+ LDL + ++ I G F L NL+ L
Sbjct: 143 AFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYL 202
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
L+ + I + N L I F L L L + + + +
Sbjct: 203 NLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIER 260
Query: 179 VEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
F++L+ L ++L N L+ +P + F+ +LE++ L N
Sbjct: 261 NAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
>AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled receptor
48 protein.
Length = 951
Score = 111 bits (266), Expect = 3e-23
Identities = 88/303 (29%), Positives = 132/303 (43%), Gaps = 8/303 (2%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ LP F++ L+ L+L N L I +A + K+L + L NN L T+P +
Sbjct: 67 NNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIR 126
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
+ L+++ + N + VP DSF GL L+ L L N + + S L LQ L L+
Sbjct: 127 GLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLAL 186
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
NKI++I D AF N NK++ + F+ L L LDLS NNL +
Sbjct: 187 NKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQA-IK 245
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
+ L+ L N++S IPD F L + L N L F+ +A +
Sbjct: 246 ARPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSASHNLSDLHSLVIRG 305
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN-----PWHCDC 297
+ F + +L +L L G S+P+ L + LS N P C
Sbjct: 306 ASMVQ-QFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGC 364
Query: 298 HAL 300
HAL
Sbjct: 365 HAL 367
Score = 92.7 bits (220), Expect = 1e-17
Identities = 80/306 (26%), Positives = 134/306 (43%), Gaps = 25/306 (8%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ +P FE LV L+ L L N L E+ ++ L + L+ N + ++P+ F
Sbjct: 139 NHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFT 198
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
N + L + + NN++ + F GL +L+ LDLS N + + +L+ L N
Sbjct: 199 NLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQAIKARPSLKELGFHSN 258
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLM----SLAG- 178
I+ I D AF+ N L + +NL L L + +++ +L G
Sbjct: 259 SISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSASHNLSDLHSLVIRGASMVQQFPNLTGT 318
Query: 179 VEFESL------------------KLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
V ESL K+LR LDL N + +P +F+ C LE++ L +N+
Sbjct: 319 VHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLP--SFNGCHALEEISLQRNQ 376
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ I F G +E+H +AF+ L +T L + N S P+ + +
Sbjct: 377 IYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGPNGL 436
Query: 281 PKLTIV 286
+L +V
Sbjct: 437 NQLKLV 442
Score = 89.0 bits (211), Expect = 2e-16
Identities = 69/247 (27%), Positives = 103/247 (41%), Gaps = 5/247 (2%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
VD S L +PE L A F + +DIS N + +P D+F L+ L L+ N + I
Sbjct: 41 VDCSGKGLTAVPEGLSA---FTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIH 97
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
S LK L++L L +N++ + A D N + ++P F L L
Sbjct: 98 PKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRH 157
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
L L +N+L + +L L+ L L N +S IPD F++ +L L L NK+R ++
Sbjct: 158 LWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLS 217
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
F G E +A +L L N +P D P L
Sbjct: 218 QHCFDGLDNLETLDLSYNNLGEFP-QAIKARPSLKELGFHSNSISVIPDGAFDGNPLLRT 276
Query: 286 VKLSGNP 292
+ L NP
Sbjct: 277 IHLYDNP 283
Score = 86.6 bits (205), Expect = 8e-16
Identities = 60/212 (28%), Positives = 97/212 (45%), Gaps = 2/212 (0%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
+ L + N + ++ +AF + L + L+ N L + K + L+ + + NN++
Sbjct: 60 QALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKT 119
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXX 139
VPS++ GL +LQ L L N I ++ +F L L+ L L DN + + + N
Sbjct: 120 VPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTL 179
Query: 140 XXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ 199
NK+ +IP F NL L+ L L NN + L+ F+ L L LDL N L +
Sbjct: 180 QALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGE 239
Query: 200 IPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
P +L++L N + I AF G
Sbjct: 240 FP-QAIKARPSLKELGFHSNSISVIPDGAFDG 270
Score = 76.6 bits (180), Expect = 9e-13
Identities = 77/313 (24%), Positives = 131/313 (41%), Gaps = 27/313 (8%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ +P L L++LRL N++ + ++F +L H+ L +N L +P
Sbjct: 114 NNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPL 173
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
+N L+ + ++ N++ +P +F L SL +L L NKI+ + F L NL+ L LS
Sbjct: 174 SNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLS 233
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNN---------- 171
N + A + N + IP F+ L + L +N
Sbjct: 234 YNNLGEF-PQAIKARPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAS 292
Query: 172 -NLMSLAGV---------EFESLK---LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSK 218
NL L + +F +L L +L L +S IP+N + L LDLS
Sbjct: 293 HNLSDLHSLVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSY 352
Query: 219 NKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLD 278
N +R ++ +F G Y++ F L +L L L N+ + SR
Sbjct: 353 NNIR--DLPSFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFA 410
Query: 279 YMPKLTIVKLSGN 291
+ +T + +S N
Sbjct: 411 TLGPITNLDVSFN 423
Score = 42.3 bits (95), Expect = 0.018
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 2/114 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ LP F L+ + LQRN + +I F L +DLS N ++ + + FA
Sbjct: 353 NNIRDLPS--FNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFA 410
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQI 117
+ +D+S N + P++ GL L+++ K K +L++L +
Sbjct: 411 TLGPITNLDVSFNELTSFPTEGPNGLNQLKLVGNFKLKEALAAKDFVNLRSLSV 464
>AB046800-1|BAB13406.1| 640|Homo sapiens KIAA1580 protein protein.
Length = 640
Score = 111 bits (266), Expect = 3e-23
Identities = 79/272 (29%), Positives = 127/272 (46%), Gaps = 4/272 (1%)
Query: 65 NTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDN 123
+T +++ N++ + +SF L L+IL LS+N I+ I+ G F+ L NL L+L DN
Sbjct: 75 STNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDN 134
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMS-LAGVEFE 182
++ I + AF N +++IP+ FN + L LDL +S ++ FE
Sbjct: 135 RLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFE 194
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L LR L+L L +IP+ T L++LDLS N L I +F G
Sbjct: 195 GLSNLRYLNLAMCNLREIPNLT--PLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQ 252
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYI 302
+ AF L++L + L N LP + L + L NPW+C+C L++
Sbjct: 253 SQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWL 312
Query: 303 SAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKL 334
S W++ C +P L+G ++ +L
Sbjct: 313 SWWIKDMAPSNTACCARCNTPPNLKGRYIGEL 344
Score = 76.2 bits (179), Expect = 1e-12
Identities = 56/208 (26%), Positives = 104/208 (50%), Gaps = 4/208 (1%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L N ++ I +F + L + LS N++ T+ F L T+++ +NR+
Sbjct: 77 NTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRL 136
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD-NKINNISDNAFENX 136
+P+ +F+ L L+ L L N I++I + F+ + +L+ L L + +++ IS+ AFE
Sbjct: 137 TTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGL 196
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
L+ IP L L LDLS N+L ++ F+ L L+ L + ++
Sbjct: 197 SNLRYLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQ 254
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ I N F + +L +++L+ N L +
Sbjct: 255 IQVIERNAFDNLQSLVEINLAHNNLTLL 282
Score = 74.5 bits (175), Expect = 4e-12
Identities = 57/221 (25%), Positives = 105/221 (47%), Gaps = 4/221 (1%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N ++ + F+ L +L+ L+L RN++ I+ AF L ++L +N L T+P
Sbjct: 83 LHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNG 142
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSK-NKIQNIQNGTF-SLKNLQIL 118
F + L+ + + NN + +PS +F + SL+ LDL + ++ I G F L NL+ L
Sbjct: 143 AFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYL 202
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
L+ + I + N L I F L L L + + + +
Sbjct: 203 NLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIER 260
Query: 179 VEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
F++L+ L ++L N L+ +P + F+ +LE++ L N
Sbjct: 261 NAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
>BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 109 bits (263), Expect = 8e-23
Identities = 85/289 (29%), Positives = 126/289 (43%), Gaps = 3/289 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ L SL L+ LRL N L I AFT L + L NN L +P +
Sbjct: 76 NNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQ 135
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
N L+++ + N + YVP F GL+SL+ L L N + I F SL LQ + L+
Sbjct: 136 NLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLAL 195
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
NKI++I D AF N N++ ++ + F+ L L LDL+ NNL
Sbjct: 196 NKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP-TAIR 254
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
+L L+ L N + IP+ F +L + N ++F+ +AF
Sbjct: 255 TLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNG 314
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
F + NL +L L G SLP + +P L ++ LS N
Sbjct: 315 ASQI-TEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYN 362
Score = 107 bits (256), Expect = 6e-22
Identities = 89/311 (28%), Positives = 136/311 (43%), Gaps = 28/311 (9%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ Y+P F L +L+ L L N L EI +AF S L + L+ N ++ +P+ F
Sbjct: 148 NHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFG 207
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
N + L + + NNR+ + F GL+SL+ LDL+ N + +L NL+ L N
Sbjct: 208 NLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSN 267
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLS-------------- 169
I +I + AF N ++ + F +L L L L+
Sbjct: 268 NIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT 327
Query: 170 -NNNLMSLAGVEFESLKL--------LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
N ++L G + SL L+ LDL N L +P +FS C L+K+DL N+
Sbjct: 328 ANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLP--SFSVCQKLQKIDLRHNE 385
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ I + F +H AFS L +L L L N+ S P + +
Sbjct: 386 IYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFP---ITGL 442
Query: 281 PKLTIVKLSGN 291
LT +KL+GN
Sbjct: 443 HGLTHLKLTGN 453
Score = 101 bits (243), Expect = 2e-20
Identities = 75/245 (30%), Positives = 107/245 (43%), Gaps = 2/245 (0%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
L L N + ++ S + L + L+ N L +P+ F L+ + + NN++ +VP
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXX 141
+++ L SLQ L L N I + FS L +L+ L L DN + I AF +
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQA 190
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
NK+ +IP F NL L+ L L NN + SL F+ L L LDL N L + P
Sbjct: 191 MTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP 250
Query: 202 DNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT 261
NL++L N +R I AF G V AF L L T
Sbjct: 251 -TAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRT 309
Query: 262 LYLDG 266
L L+G
Sbjct: 310 LTLNG 314
Score = 93.9 bits (223), Expect = 6e-18
Identities = 68/247 (27%), Positives = 111/247 (44%), Gaps = 4/247 (1%)
Query: 46 HVDLS-NNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQN 104
++DLS NN LP L + FLE + ++ N + Y+P +F GLYSL++L L N++++
Sbjct: 70 YLDLSMNNISQLLPNPL-PSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRH 128
Query: 105 IQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCL 163
+ +L++LQ L+L N I+ + + F D N L IP Q F +L L
Sbjct: 129 VPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSAL 188
Query: 164 IFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRF 223
+ L+ N + + F +L L L L N + + F +LE LDL+ N L
Sbjct: 189 QAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDE 248
Query: 224 INITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKL 283
TA + KAF +L T++ N + ++P+L
Sbjct: 249 FP-TAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPEL 307
Query: 284 TIVKLSG 290
+ L+G
Sbjct: 308 RTLTLNG 314
Score = 91.1 bits (216), Expect = 4e-17
Identities = 67/272 (24%), Positives = 114/272 (41%), Gaps = 3/272 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + Y+P G F L +LK L LQ N L + +EA + + L + L N++ +P F+
Sbjct: 100 NALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFS 159
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L + + +N + +P +F L +LQ + L+ NKI +I + F +L +L +L L +
Sbjct: 160 GLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHN 219
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I+++ F+ + N L PT + L L L +NN+ S+ F
Sbjct: 220 NRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAI-RTLSNLKELGFHSNNIRSIPEKAFV 278
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L + +N + + + F L L L+ + G
Sbjct: 279 GNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLN-GASQITEFPDLTGTANLESLTLTG 337
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPS 274
+ + L NL L L N+ LPS
Sbjct: 338 AQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS 369
Score = 84.2 bits (199), Expect = 5e-15
Identities = 66/252 (26%), Positives = 103/252 (40%), Gaps = 5/252 (1%)
Query: 42 KKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNK 101
+ L VD S+ L LP L + F +D+S N + + + L L+ L L+ N
Sbjct: 45 RMLLRVDCSDLGLSELPSNL---SVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNA 101
Query: 102 IQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNL 160
+ I G F+ L +L++L L +N++ ++ A +N D N + +P F+ L
Sbjct: 102 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGL 161
Query: 161 KCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
L L L +N L + F SL L+ + L N + IPD F + +L L L N+
Sbjct: 162 HSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNR 221
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ + F G E A L NL L N S+P +
Sbjct: 222 IHSLGKKCFDGLHSLETLDLNYNNLDEFP-TAIRTLSNLKELGFHSNNIRSIPEKAFVGN 280
Query: 281 PKLTIVKLSGNP 292
P L + NP
Sbjct: 281 PSLITIHFYDNP 292
Score = 83.0 bits (196), Expect = 1e-14
Identities = 66/232 (28%), Positives = 112/232 (48%), Gaps = 5/232 (2%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N + L F+ L +L+TL L N L+E + A + L + +N + ++PEK
Sbjct: 217 LHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELGFHSNNIRSIPEK 275
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLS-KNKIQNIQNGTFSLKNLQILK 119
F N L TI +N + +V +F L L+ L L+ ++I + T NL+ L
Sbjct: 276 AFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLT-GTANLESLT 334
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
L+ +I+++ N L+++P+ F+ + L +DL +N + +
Sbjct: 335 LTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS--FSVCQKLQKIDLRHNEIYEIKVD 392
Query: 180 EFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
F+ L LR+L+L N ++ I N FS +L KLDLS N L IT +G
Sbjct: 393 TFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFPITGLHG 444
Score = 80.6 bits (190), Expect = 6e-14
Identities = 55/217 (25%), Positives = 106/217 (48%), Gaps = 5/217 (2%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + ++P ++L +L++LRL N++ + F+ L H+ L +N L +P + F
Sbjct: 123 NNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAF 182
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
+ + L+ + ++ N++ ++P +F L SL +L L N+I ++ F L +L+ L L+
Sbjct: 183 RSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 242
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N ++ A N +++IP + F LI + +N + + F
Sbjct: 243 YNNLDEF-PTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAF 301
Query: 182 ESLKLLRNLDLK-ENALSQIPDNTFSDCFNLEKLDLS 217
+ L LR L L + +++ PD T NLE L L+
Sbjct: 302 QHLPELRTLTLNGASQITEFPDLT--GTANLESLTLT 336
>BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 109 bits (263), Expect = 8e-23
Identities = 85/289 (29%), Positives = 126/289 (43%), Gaps = 3/289 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ L SL L+ LRL N L I AFT L + L NN L +P +
Sbjct: 76 NNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQ 135
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
N L+++ + N + YVP F GL+SL+ L L N + I F SL LQ + L+
Sbjct: 136 NLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLAL 195
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
NKI++I D AF N N++ ++ + F+ L L LDL+ NNL
Sbjct: 196 NKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP-TAIR 254
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
+L L+ L N + IP+ F +L + N ++F+ +AF
Sbjct: 255 TLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNG 314
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
F + NL +L L G SLP + +P L ++ LS N
Sbjct: 315 ASQI-TEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYN 362
Score = 107 bits (256), Expect = 6e-22
Identities = 89/311 (28%), Positives = 136/311 (43%), Gaps = 28/311 (9%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ Y+P F L +L+ L L N L EI +AF S L + L+ N ++ +P+ F
Sbjct: 148 NHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFG 207
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
N + L + + NNR+ + F GL+SL+ LDL+ N + +L NL+ L N
Sbjct: 208 NLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSN 267
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLS-------------- 169
I +I + AF N ++ + F +L L L L+
Sbjct: 268 NIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT 327
Query: 170 -NNNLMSLAGVEFESLKL--------LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
N ++L G + SL L+ LDL N L +P +FS C L+K+DL N+
Sbjct: 328 ANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLP--SFSVCQKLQKIDLRHNE 385
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ I + F +H AFS L +L L L N+ S P + +
Sbjct: 386 IYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFP---ITGL 442
Query: 281 PKLTIVKLSGN 291
LT +KL+GN
Sbjct: 443 HGLTHLKLTGN 453
Score = 101 bits (243), Expect = 2e-20
Identities = 75/245 (30%), Positives = 107/245 (43%), Gaps = 2/245 (0%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
L L N + ++ S + L + L+ N L +P+ F L+ + + NN++ +VP
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXX 141
+++ L SLQ L L N I + FS L +L+ L L DN + I AF +
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQA 190
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
NK+ +IP F NL L+ L L NN + SL F+ L L LDL N L + P
Sbjct: 191 MTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP 250
Query: 202 DNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT 261
NL++L N +R I AF G V AF L L T
Sbjct: 251 -TAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRT 309
Query: 262 LYLDG 266
L L+G
Sbjct: 310 LTLNG 314
Score = 93.9 bits (223), Expect = 6e-18
Identities = 68/247 (27%), Positives = 111/247 (44%), Gaps = 4/247 (1%)
Query: 46 HVDLS-NNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQN 104
++DLS NN LP L + FLE + ++ N + Y+P +F GLYSL++L L N++++
Sbjct: 70 YLDLSMNNISQLLPNPL-PSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRH 128
Query: 105 IQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCL 163
+ +L++LQ L+L N I+ + + F D N L IP Q F +L L
Sbjct: 129 VPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSAL 188
Query: 164 IFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRF 223
+ L+ N + + F +L L L L N + + F +LE LDL+ N L
Sbjct: 189 QAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDE 248
Query: 224 INITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKL 283
TA + KAF +L T++ N + ++P+L
Sbjct: 249 FP-TAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPEL 307
Query: 284 TIVKLSG 290
+ L+G
Sbjct: 308 RTLTLNG 314
Score = 91.1 bits (216), Expect = 4e-17
Identities = 67/272 (24%), Positives = 114/272 (41%), Gaps = 3/272 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + Y+P G F L +LK L LQ N L + +EA + + L + L N++ +P F+
Sbjct: 100 NALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFS 159
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L + + +N + +P +F L +LQ + L+ NKI +I + F +L +L +L L +
Sbjct: 160 GLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHN 219
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I+++ F+ + N L PT + L L L +NN+ S+ F
Sbjct: 220 NRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAI-RTLSNLKELGFHSNNIRSIPEKAFV 278
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L + +N + + + F L L L+ + G
Sbjct: 279 GNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLN-GASQITEFPDLTGTANLESLTLTG 337
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPS 274
+ + L NL L L N+ LPS
Sbjct: 338 AQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS 369
Score = 84.2 bits (199), Expect = 5e-15
Identities = 66/252 (26%), Positives = 103/252 (40%), Gaps = 5/252 (1%)
Query: 42 KKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNK 101
+ L VD S+ L LP L + F +D+S N + + + L L+ L L+ N
Sbjct: 45 RMLLRVDCSDLGLSELPSNL---SVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNA 101
Query: 102 IQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNL 160
+ I G F+ L +L++L L +N++ ++ A +N D N + +P F+ L
Sbjct: 102 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGL 161
Query: 161 KCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
L L L +N L + F SL L+ + L N + IPD F + +L L L N+
Sbjct: 162 HSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNR 221
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ + F G E A L NL L N S+P +
Sbjct: 222 IHSLGKKCFDGLHSLETLDLNYNNLDEFP-TAIRTLSNLKELGFHSNNIRSIPEKAFVGN 280
Query: 281 PKLTIVKLSGNP 292
P L + NP
Sbjct: 281 PSLITIHFYDNP 292
Score = 83.0 bits (196), Expect = 1e-14
Identities = 66/232 (28%), Positives = 112/232 (48%), Gaps = 5/232 (2%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N + L F+ L +L+TL L N L+E + A + L + +N + ++PEK
Sbjct: 217 LHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELGFHSNNIRSIPEK 275
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLS-KNKIQNIQNGTFSLKNLQILK 119
F N L TI +N + +V +F L L+ L L+ ++I + T NL+ L
Sbjct: 276 AFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLT-GTANLESLT 334
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
L+ +I+++ N L+++P+ F+ + L +DL +N + +
Sbjct: 335 LTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS--FSVCQKLQKIDLRHNEIYEIKVD 392
Query: 180 EFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
F+ L LR+L+L N ++ I N FS +L KLDLS N L IT +G
Sbjct: 393 TFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFPITGLHG 444
Score = 80.6 bits (190), Expect = 6e-14
Identities = 55/217 (25%), Positives = 106/217 (48%), Gaps = 5/217 (2%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + ++P ++L +L++LRL N++ + F+ L H+ L +N L +P + F
Sbjct: 123 NNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAF 182
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
+ + L+ + ++ N++ ++P +F L SL +L L N+I ++ F L +L+ L L+
Sbjct: 183 RSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 242
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N ++ A N +++IP + F LI + +N + + F
Sbjct: 243 YNNLDEF-PTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAF 301
Query: 182 ESLKLLRNLDLK-ENALSQIPDNTFSDCFNLEKLDLS 217
+ L LR L L + +++ PD T NLE L L+
Sbjct: 302 QHLPELRTLTLNGASQITEFPDLT--GTANLESLTLT 336
>AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-coupled
receptor HG38 protein.
Length = 907
Score = 109 bits (263), Expect = 8e-23
Identities = 85/289 (29%), Positives = 126/289 (43%), Gaps = 3/289 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ L SL L+ LRL N L I AFT L + L NN L +P +
Sbjct: 76 NNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQ 135
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
N L+++ + N + YVP F GL+SL+ L L N + I F SL LQ + L+
Sbjct: 136 NLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLAL 195
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
NKI++I D AF N N++ ++ + F+ L L LDL+ NNL
Sbjct: 196 NKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP-TAIR 254
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
+L L+ L N + IP+ F +L + N ++F+ +AF
Sbjct: 255 TLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNG 314
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
F + NL +L L G SLP + +P L ++ LS N
Sbjct: 315 ASQI-TEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYN 362
Score = 107 bits (256), Expect = 6e-22
Identities = 89/311 (28%), Positives = 136/311 (43%), Gaps = 28/311 (9%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ Y+P F L +L+ L L N L EI +AF S L + L+ N ++ +P+ F
Sbjct: 148 NHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFG 207
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
N + L + + NNR+ + F GL+SL+ LDL+ N + +L NL+ L N
Sbjct: 208 NLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSN 267
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLS-------------- 169
I +I + AF N ++ + F +L L L L+
Sbjct: 268 NIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT 327
Query: 170 -NNNLMSLAGVEFESLKL--------LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
N ++L G + SL L+ LDL N L +P +FS C L+K+DL N+
Sbjct: 328 ANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLP--SFSVCQKLQKIDLRHNE 385
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ I + F +H AFS L +L L L N+ S P + +
Sbjct: 386 IYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFP---ITGL 442
Query: 281 PKLTIVKLSGN 291
LT +KL+GN
Sbjct: 443 HGLTHLKLTGN 453
Score = 101 bits (243), Expect = 2e-20
Identities = 75/245 (30%), Positives = 107/245 (43%), Gaps = 2/245 (0%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
L L N + ++ S + L + L+ N L +P+ F L+ + + NN++ +VP
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXX 141
+++ L SLQ L L N I + FS L +L+ L L DN + I AF +
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQA 190
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
NK+ +IP F NL L+ L L NN + SL F+ L L LDL N L + P
Sbjct: 191 MTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP 250
Query: 202 DNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT 261
NL++L N +R I AF G V AF L L T
Sbjct: 251 -TAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRT 309
Query: 262 LYLDG 266
L L+G
Sbjct: 310 LTLNG 314
Score = 93.9 bits (223), Expect = 6e-18
Identities = 68/247 (27%), Positives = 111/247 (44%), Gaps = 4/247 (1%)
Query: 46 HVDLS-NNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQN 104
++DLS NN LP L + FLE + ++ N + Y+P +F GLYSL++L L N++++
Sbjct: 70 YLDLSMNNISQLLPNPL-PSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRH 128
Query: 105 IQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCL 163
+ +L++LQ L+L N I+ + + F D N L IP Q F +L L
Sbjct: 129 VPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSAL 188
Query: 164 IFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRF 223
+ L+ N + + F +L L L L N + + F +LE LDL+ N L
Sbjct: 189 QAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDE 248
Query: 224 INITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKL 283
TA + KAF +L T++ N + ++P+L
Sbjct: 249 FP-TAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPEL 307
Query: 284 TIVKLSG 290
+ L+G
Sbjct: 308 RTLTLNG 314
Score = 91.1 bits (216), Expect = 4e-17
Identities = 67/272 (24%), Positives = 114/272 (41%), Gaps = 3/272 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + Y+P G F L +LK L LQ N L + +EA + + L + L N++ +P F+
Sbjct: 100 NALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFS 159
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L + + +N + +P +F L +LQ + L+ NKI +I + F +L +L +L L +
Sbjct: 160 GLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHN 219
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I+++ F+ + N L PT + L L L +NN+ S+ F
Sbjct: 220 NRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAI-RTLSNLKELGFHSNNIRSIPEKAFV 278
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L + +N + + + F L L L+ + G
Sbjct: 279 GNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLN-GASQITEFPDLTGTANLESLTLTG 337
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPS 274
+ + L NL L L N+ LPS
Sbjct: 338 AQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS 369
Score = 84.2 bits (199), Expect = 5e-15
Identities = 66/252 (26%), Positives = 103/252 (40%), Gaps = 5/252 (1%)
Query: 42 KKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNK 101
+ L VD S+ L LP L + F +D+S N + + + L L+ L L+ N
Sbjct: 45 RMLLRVDCSDLGLSELPSNL---SVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNA 101
Query: 102 IQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNL 160
+ I G F+ L +L++L L +N++ ++ A +N D N + +P F+ L
Sbjct: 102 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGL 161
Query: 161 KCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
L L L +N L + F SL L+ + L N + IPD F + +L L L N+
Sbjct: 162 HSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNR 221
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ + F G E A L NL L N S+P +
Sbjct: 222 IHSLGKKCFDGLHSLETLDLNYNNLDEFP-TAIRTLSNLKELGFHSNNIRSIPEKAFVGN 280
Query: 281 PKLTIVKLSGNP 292
P L + NP
Sbjct: 281 PSLITIHFYDNP 292
Score = 83.0 bits (196), Expect = 1e-14
Identities = 66/232 (28%), Positives = 112/232 (48%), Gaps = 5/232 (2%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N + L F+ L +L+TL L N L+E + A + L + +N + ++PEK
Sbjct: 217 LHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELGFHSNNIRSIPEK 275
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLS-KNKIQNIQNGTFSLKNLQILK 119
F N L TI +N + +V +F L L+ L L+ ++I + T NL+ L
Sbjct: 276 AFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLT-GTANLESLT 334
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
L+ +I+++ N L+++P+ F+ + L +DL +N + +
Sbjct: 335 LTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS--FSVCQKLQKIDLRHNEIYEIKVD 392
Query: 180 EFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
F+ L LR+L+L N ++ I N FS +L KLDLS N L IT +G
Sbjct: 393 TFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFPITGLHG 444
Score = 80.6 bits (190), Expect = 6e-14
Identities = 55/217 (25%), Positives = 106/217 (48%), Gaps = 5/217 (2%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + ++P ++L +L++LRL N++ + F+ L H+ L +N L +P + F
Sbjct: 123 NNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAF 182
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
+ + L+ + ++ N++ ++P +F L SL +L L N+I ++ F L +L+ L L+
Sbjct: 183 RSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 242
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N ++ A N +++IP + F LI + +N + + F
Sbjct: 243 YNNLDEF-PTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAF 301
Query: 182 ESLKLLRNLDLK-ENALSQIPDNTFSDCFNLEKLDLS 217
+ L LR L L + +++ PD T NLE L L+
Sbjct: 302 QHLPELRTLTLNGASQITEFPDLT--GTANLESLTLT 336
>AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled receptor
LGR5 protein.
Length = 907
Score = 109 bits (262), Expect = 1e-22
Identities = 85/289 (29%), Positives = 126/289 (43%), Gaps = 3/289 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ L SL L+ LRL N L I AFT L + L NN L +P +
Sbjct: 76 NNISQLLPNPLPSLHFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQ 135
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
N L+++ + N + YVP F GL+SL+ L L N + I F SL LQ + L+
Sbjct: 136 NLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLAL 195
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
NKI++I D AF N N++ ++ + F+ L L LDL+ NNL
Sbjct: 196 NKIHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP-TAIR 254
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
+L L+ L N + IP+ F +L + N ++F+ +AF
Sbjct: 255 TLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNG 314
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
F + NL +L L G SLP + +P L ++ LS N
Sbjct: 315 ASQI-TEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYN 362
Score = 104 bits (250), Expect = 3e-21
Identities = 88/311 (28%), Positives = 135/311 (43%), Gaps = 28/311 (9%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ Y+P F L +L+ L L N L EI +AF S L + L+ N ++ +P+ F
Sbjct: 148 NHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFG 207
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
N + + + NNR+ + F GL+SL+ LDL+ N + +L NL+ L N
Sbjct: 208 NLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSN 267
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLS-------------- 169
I +I + AF N ++ + F +L L L L+
Sbjct: 268 NIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT 327
Query: 170 -NNNLMSLAGVEFESLKL--------LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
N ++L G + SL L+ LDL N L +P +FS C L+K+DL N+
Sbjct: 328 ANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLP--SFSVCQKLQKIDLRHNE 385
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ I + F +H AFS L +L L L N+ S P + +
Sbjct: 386 IYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFP---ITGL 442
Query: 281 PKLTIVKLSGN 291
LT +KL+GN
Sbjct: 443 HGLTHLKLTGN 453
Score = 98.3 bits (234), Expect = 3e-19
Identities = 74/245 (30%), Positives = 105/245 (42%), Gaps = 2/245 (0%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
L L N + ++ S L + L+ N L +P+ F L+ + + NN++ +VP
Sbjct: 71 LDLSMNNISQLLPNPLPSLHFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXX 141
+++ L SLQ L L N I + FS L +L+ L L DN + I AF +
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQA 190
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
NK+ +IP F NL + L L NN + SL F+ L L LDL N L + P
Sbjct: 191 MTLALNKIHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP 250
Query: 202 DNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT 261
NL++L N +R I AF G V AF L L T
Sbjct: 251 -TAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRT 309
Query: 262 LYLDG 266
L L+G
Sbjct: 310 LTLNG 314
Score = 91.1 bits (216), Expect = 4e-17
Identities = 67/247 (27%), Positives = 111/247 (44%), Gaps = 4/247 (1%)
Query: 46 HVDLS-NNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQN 104
++DLS NN LP L + + FLE + ++ N + Y+P +F GLYSL++L L N++++
Sbjct: 70 YLDLSMNNISQLLPNPLPSLH-FLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRH 128
Query: 105 IQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCL 163
+ +L++LQ L+L N I+ + + F D N L IP Q F +L L
Sbjct: 129 VPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSAL 188
Query: 164 IFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRF 223
+ L+ N + + F +L L L N + + F +LE LDL+ N L
Sbjct: 189 QAMTLALNKIHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDE 248
Query: 224 INITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKL 283
TA + KAF +L T++ N + ++P+L
Sbjct: 249 FP-TAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPEL 307
Query: 284 TIVKLSG 290
+ L+G
Sbjct: 308 RTLTLNG 314
Score = 88.6 bits (210), Expect = 2e-16
Identities = 66/272 (24%), Positives = 113/272 (41%), Gaps = 3/272 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + Y+P G F L +LK L LQ N L + +EA + + L + L N++ +P F+
Sbjct: 100 NALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFS 159
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L + + +N + +P +F L +LQ + L+ NKI +I + F +L + +L L +
Sbjct: 160 GLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSWVVLHLHN 219
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I+++ F+ + N L PT + L L L +NN+ S+ F
Sbjct: 220 NRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAI-RTLSNLKELGFHSNNIRSIPEKAFV 278
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L + +N + + + F L L L+ + G
Sbjct: 279 GNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLN-GASQITEFPDLTGTANLESLTLTG 337
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPS 274
+ + L NL L L N+ LPS
Sbjct: 338 AQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS 369
Score = 83.4 bits (197), Expect = 8e-15
Identities = 65/252 (25%), Positives = 103/252 (40%), Gaps = 5/252 (1%)
Query: 42 KKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNK 101
+ L VD S+ L LP L + F +D+S N + + + L+ L+ L L+ N
Sbjct: 45 RMLLRVDCSDLGLSELPSNL---SVFTSYLDLSMNNISQLLPNPLPSLHFLEELRLAGNA 101
Query: 102 IQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNL 160
+ I G F+ L +L++L L +N++ ++ A +N D N + +P F+ L
Sbjct: 102 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGL 161
Query: 161 KCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
L L L +N L + F SL L+ + L N + IPD F + + L L N+
Sbjct: 162 HSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSWVVLHLHNNR 221
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ + F G E A L NL L N S+P +
Sbjct: 222 IHSLGKKCFDGLHSLETLDLNYNNLDEFP-TAIRTLSNLKELGFHSNNIRSIPEKAFVGN 280
Query: 281 PKLTIVKLSGNP 292
P L + NP
Sbjct: 281 PSLITIHFYDNP 292
Score = 83.0 bits (196), Expect = 1e-14
Identities = 66/232 (28%), Positives = 112/232 (48%), Gaps = 5/232 (2%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N + L F+ L +L+TL L N L+E + A + L + +N + ++PEK
Sbjct: 217 LHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELGFHSNNIRSIPEK 275
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLS-KNKIQNIQNGTFSLKNLQILK 119
F N L TI +N + +V +F L L+ L L+ ++I + T NL+ L
Sbjct: 276 AFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLT-GTANLESLT 334
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
L+ +I+++ N L+++P+ F+ + L +DL +N + +
Sbjct: 335 LTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS--FSVCQKLQKIDLRHNEIYEIKVD 392
Query: 180 EFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
F+ L LR+L+L N ++ I N FS +L KLDLS N L IT +G
Sbjct: 393 TFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFPITGLHG 444
Score = 78.2 bits (184), Expect = 3e-13
Identities = 54/217 (24%), Positives = 105/217 (48%), Gaps = 5/217 (2%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + ++P ++L +L++LRL N++ + F+ L H+ L +N L +P + F
Sbjct: 123 NNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAF 182
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
+ + L+ + ++ N++ ++P +F L S +L L N+I ++ F L +L+ L L+
Sbjct: 183 RSLSALQAMTLALNKIHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 242
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N ++ A N +++IP + F LI + +N + + F
Sbjct: 243 YNNLDEF-PTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAF 301
Query: 182 ESLKLLRNLDLK-ENALSQIPDNTFSDCFNLEKLDLS 217
+ L LR L L + +++ PD T NLE L L+
Sbjct: 302 QHLPELRTLTLNGASQITEFPDLT--GTANLESLTLT 336
>AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 967
Score = 107 bits (258), Expect = 3e-22
Identities = 74/246 (30%), Positives = 114/246 (46%), Gaps = 2/246 (0%)
Query: 46 HVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI 105
++DLS N L L LF + FLE + +S N + ++P +F GLYSL+IL L N++ I
Sbjct: 70 YLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGI 129
Query: 106 Q-NGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLI 164
+ L +LQ L+L N I+ + + +FE D N L IP + NNL L
Sbjct: 130 PAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQ 189
Query: 165 FLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ L+ N + + F++L L L L N + + ++F NLE LDL+ NKL+
Sbjct: 190 AMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEF 249
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
+ A + KAF L T++ N + Y+PKL
Sbjct: 250 PV-AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLH 308
Query: 285 IVKLSG 290
+ L+G
Sbjct: 309 TLSLNG 314
Score = 100 bits (239), Expect = 6e-20
Identities = 80/289 (27%), Positives = 127/289 (43%), Gaps = 3/289 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ L G+F L L+ LRL N+L I +AF+ L + L NN L +P +
Sbjct: 76 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 135
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ-NGTFSLKNLQILKLSD 122
L+++ + N + VP SF GL SL+ L L N + I +L LQ + L+
Sbjct: 136 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 195
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I++I D AF+N N+++++ T F L L LDL+ N L V
Sbjct: 196 NRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFP-VAIR 254
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
+L L+ L N + IP+ F L+ + N ++F+ +AF
Sbjct: 255 TLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG 314
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ F +L L L LPS +P+L +++LS N
Sbjct: 315 AMDIQ-EFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHN 362
Score = 98.3 bits (234), Expect = 3e-19
Identities = 78/259 (30%), Positives = 110/259 (42%), Gaps = 6/259 (2%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
L L N L E+ F + L + LS N+L +P + F+ L+ + + NN++ +P
Sbjct: 71 LDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIP 130
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXX 141
+++ L SLQ L L N I + +F L +L+ L L DN + I A N
Sbjct: 131 AEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQA 190
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
N++ +IP F NL L+ L L NN + L FE L L LDL N L + P
Sbjct: 191 MTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFP 250
Query: 202 DNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT 261
L++L N ++ I AF G V AF L L T
Sbjct: 251 -VAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHT 309
Query: 262 LYLDGNM----FPSLPSRT 276
L L+G M FP L T
Sbjct: 310 LSLNGAMDIQEFPDLKGTT 328
Score = 87.8 bits (208), Expect = 4e-16
Identities = 84/311 (27%), Positives = 130/311 (41%), Gaps = 28/311 (9%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + +P FE L +L+ L L N L EI A + L + L+ N + +P+ F
Sbjct: 148 NLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQ 207
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
N T L + + NNR+ ++ + SF GL++L+ LDL+ NK+Q +L LQ L +N
Sbjct: 208 NLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNN 267
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLI------------FLDLSNN 171
I I + AF N ++ + F L L F DL
Sbjct: 268 NIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGT 327
Query: 172 NLMSL-----AGVEF------ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
+ + AG+ + L LR L+L N + ++P + C LE++ L N+
Sbjct: 328 TSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP--SLHRCQKLEEIGLQHNR 385
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ I F +H +AFS L +L L L N +LP L +
Sbjct: 386 IWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP---LAGL 442
Query: 281 PKLTIVKLSGN 291
L +KL GN
Sbjct: 443 GGLMHLKLKGN 453
Score = 82.6 bits (195), Expect = 1e-14
Identities = 64/233 (27%), Positives = 105/233 (45%), Gaps = 7/233 (3%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N +++L FE L NL+TL L N L+E A + +L + NN + +PEK
Sbjct: 217 LHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPV-AIRTLGRLQELGFHNNNIKAIPEK 275
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQN--GTFSLKNLQIL 118
F N L+TI +N + +V +F L L L L N +IQ +L+IL
Sbjct: 276 AFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSL--NGAMDIQEFPDLKGTTSLEIL 333
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
L+ I + + N+++ +P+ + + L + L +N + +
Sbjct: 334 TLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGA 391
Query: 179 VEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
F L L+ LDL NA+ I FS +L KLDL+ N+L + + G
Sbjct: 392 DTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGG 444
Score = 74.9 bits (176), Expect = 3e-12
Identities = 57/224 (25%), Positives = 100/224 (44%), Gaps = 5/224 (2%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + +P L +L++LRL N + + +F L H+ L +N L +P +
Sbjct: 123 NNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRAL 182
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
N L+ + ++ NR+ ++P +F L SL +L L N+IQ++ +F L NL+ L L+
Sbjct: 183 NNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLN 242
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
NK+ A N +K IP + F L + +N + + F
Sbjct: 243 YNKLQEF-PVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAF 301
Query: 182 ESLKLLRNLDLK-ENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ L L L L + + PD +LE L L++ +R +
Sbjct: 302 QYLPKLHTLSLNGAMDIQEFPD--LKGTTSLEILTLTRAGIRLL 343
>AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein.
Length = 928
Score = 107 bits (258), Expect = 3e-22
Identities = 74/246 (30%), Positives = 114/246 (46%), Gaps = 2/246 (0%)
Query: 46 HVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI 105
++DLS N L L LF + FLE + +S N + ++P +F GLYSL+IL L N++ I
Sbjct: 31 YLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGI 90
Query: 106 Q-NGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLI 164
+ L +LQ L+L N I+ + + +FE D N L IP + NNL L
Sbjct: 91 PAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQ 150
Query: 165 FLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ L+ N + + F++L L L L N + + ++F NLE LDL+ NKL+
Sbjct: 151 AMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEF 210
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
+ A + KAF L T++ N + Y+PKL
Sbjct: 211 PV-AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLH 269
Query: 285 IVKLSG 290
+ L+G
Sbjct: 270 TLSLNG 275
Score = 100 bits (239), Expect = 6e-20
Identities = 80/289 (27%), Positives = 127/289 (43%), Gaps = 3/289 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ L G+F L L+ LRL N+L I +AF+ L + L NN L +P +
Sbjct: 37 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 96
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ-NGTFSLKNLQILKLSD 122
L+++ + N + VP SF GL SL+ L L N + I +L LQ + L+
Sbjct: 97 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 156
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I++I D AF+N N+++++ T F L L LDL+ N L V
Sbjct: 157 NRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFP-VAIR 215
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
+L L+ L N + IP+ F L+ + N ++F+ +AF
Sbjct: 216 TLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG 275
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ F +L L L LPS +P+L +++LS N
Sbjct: 276 AMDIQ-EFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHN 323
Score = 98.3 bits (234), Expect = 3e-19
Identities = 78/259 (30%), Positives = 110/259 (42%), Gaps = 6/259 (2%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
L L N L E+ F + L + LS N+L +P + F+ L+ + + NN++ +P
Sbjct: 32 LDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIP 91
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXX 141
+++ L SLQ L L N I + +F L +L+ L L DN + I A N
Sbjct: 92 AEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQA 151
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
N++ +IP F NL L+ L L NN + L FE L L LDL N L + P
Sbjct: 152 MTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFP 211
Query: 202 DNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT 261
L++L N ++ I AF G V AF L L T
Sbjct: 212 -VAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHT 270
Query: 262 LYLDGNM----FPSLPSRT 276
L L+G M FP L T
Sbjct: 271 LSLNGAMDIQEFPDLKGTT 289
Score = 87.8 bits (208), Expect = 4e-16
Identities = 84/311 (27%), Positives = 130/311 (41%), Gaps = 28/311 (9%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + +P FE L +L+ L L N L EI A + L + L+ N + +P+ F
Sbjct: 109 NLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQ 168
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
N T L + + NNR+ ++ + SF GL++L+ LDL+ NK+Q +L LQ L +N
Sbjct: 169 NLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNN 228
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLI------------FLDLSNN 171
I I + AF N ++ + F L L F DL
Sbjct: 229 NIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGT 288
Query: 172 NLMSL-----AGVEF------ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
+ + AG+ + L LR L+L N + ++P + C LE++ L N+
Sbjct: 289 TSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP--SLHRCQKLEEIGLQHNR 346
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ I F +H +AFS L +L L L N +LP L +
Sbjct: 347 IWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP---LAGL 403
Query: 281 PKLTIVKLSGN 291
L +KL GN
Sbjct: 404 GGLMHLKLKGN 414
Score = 82.6 bits (195), Expect = 1e-14
Identities = 64/233 (27%), Positives = 105/233 (45%), Gaps = 7/233 (3%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N +++L FE L NL+TL L N L+E A + +L + NN + +PEK
Sbjct: 178 LHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPV-AIRTLGRLQELGFHNNNIKAIPEK 236
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQN--GTFSLKNLQIL 118
F N L+TI +N + +V +F L L L L N +IQ +L+IL
Sbjct: 237 AFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSL--NGAMDIQEFPDLKGTTSLEIL 294
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
L+ I + + N+++ +P+ + + L + L +N + +
Sbjct: 295 TLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGA 352
Query: 179 VEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
F L L+ LDL NA+ I FS +L KLDL+ N+L + + G
Sbjct: 353 DTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGG 405
Score = 74.9 bits (176), Expect = 3e-12
Identities = 57/224 (25%), Positives = 100/224 (44%), Gaps = 5/224 (2%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + +P L +L++LRL N + + +F L H+ L +N L +P +
Sbjct: 84 NNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRAL 143
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
N L+ + ++ NR+ ++P +F L SL +L L N+IQ++ +F L NL+ L L+
Sbjct: 144 NNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLN 203
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
NK+ A N +K IP + F L + +N + + F
Sbjct: 204 YNKLQEF-PVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAF 262
Query: 182 ESLKLLRNLDLK-ENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ L L L L + + PD +LE L L++ +R +
Sbjct: 263 QYLPKLHTLSLNGAMDIQEFPD--LKGTTSLEILTLTRAGIRLL 304
>BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein.
Length = 927
Score = 107 bits (256), Expect = 6e-22
Identities = 83/286 (29%), Positives = 127/286 (44%), Gaps = 8/286 (2%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
+ L+L N L I +A + K+L + L NN L T+P + + L+++ + N +
Sbjct: 60 QALQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITS 119
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQ-NGTFSLKNLQILKLSDNKINNISDNAFENXXXX 139
VP DSF GL L+ L L N + + + +L LQ L L+ NKI++I D AF N
Sbjct: 120 VPEDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPTLQALTLALNKISSIPDFAFTNLSSL 179
Query: 140 XXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ 199
NK++++ F+ L L LDL+ NNL ++L L+ L N++S
Sbjct: 180 VVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQA-IKALPSLKELGFHSNSISV 238
Query: 200 IPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNL 259
IPD F L + L N L F+ +AF+ + F + +L
Sbjct: 239 IPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQ-QFPNLTGTVHL 297
Query: 260 TTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN-----PWHCDCHAL 300
+L L G S+P+ L + LS N P CHAL
Sbjct: 298 ESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHAL 343
Score = 99 bits (238), Expect = 8e-20
Identities = 82/306 (26%), Positives = 137/306 (44%), Gaps = 25/306 (8%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ +P FE LV L+ L L N L E+ ++ L + L+ N + ++P+ F
Sbjct: 115 NHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPTLQALTLALNKISSIPDFAFT 174
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
N + L + + NN++ + F GL +L+ LDL+ N + +L +L+ L N
Sbjct: 175 NLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSLKELGFHSN 234
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLM----SLAG- 178
I+ I D AF+ N L + F+NL L L + +++ +L G
Sbjct: 235 SISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGT 294
Query: 179 VEFESL------------------KLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
V ESL K+LR LDL N + +P +F+ C LE++ L +N+
Sbjct: 295 VHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLP--SFNGCHALEEISLQRNQ 352
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ I F G +E+H +AF+ L +T L + N S P+ L+ +
Sbjct: 353 IYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGL 412
Query: 281 PKLTIV 286
+L +V
Sbjct: 413 NQLKLV 418
Score = 87.0 bits (206), Expect = 6e-16
Identities = 73/274 (26%), Positives = 117/274 (42%), Gaps = 7/274 (2%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + ++ L LK L LQ N L+ + SEA L + L N++ ++PE F
Sbjct: 67 NDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFE 126
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L + + +N + VP L +LQ L L+ NKI +I + F +L +L +L L +
Sbjct: 127 GLVQLRHLWLDDNSLTEVPVHHLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHN 186
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
NKI ++S + F+ + N L P Q L L L +N++ + F+
Sbjct: 187 NKIRSLSQHCFDGLDNLETLDLNYNNLGEFP-QAIKALPSLKELGFHSNSISVIPDGAFD 245
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL--RFINITAFYGXXXXXXXXX 240
LLR + L +N LS + ++ F + +L L + + +F N+T G
Sbjct: 246 GNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLT---GTVHLESLTL 302
Query: 241 XXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPS 274
+ K L TL L N LPS
Sbjct: 303 TGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPS 336
Score = 77.4 bits (182), Expect = 5e-13
Identities = 75/313 (23%), Positives = 130/313 (41%), Gaps = 27/313 (8%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ +P L L++LRL N++ + ++F +L H+ L +N L +P
Sbjct: 90 NNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHHL 149
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
+N L+ + ++ N++ +P +F L SL +L L NKI+++ F L NL+ L L+
Sbjct: 150 SNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLN 209
Query: 122 -----------------------DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFN 158
N I+ I D AF+ N L + F+
Sbjct: 210 YNNLGEFPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFH 269
Query: 159 NLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSK 218
NL L L + +++ L +L L +S IP+N + L LDLS
Sbjct: 270 NLSDLHSLVIRGASMVQ-QFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSY 328
Query: 219 NKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLD 278
N +R ++ +F G Y++ F L +L L L N+ + SR
Sbjct: 329 NNIR--DLPSFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFA 386
Query: 279 YMPKLTIVKLSGN 291
+ +T + +S N
Sbjct: 387 TLGPITNLDVSFN 399
Score = 70.1 bits (164), Expect = 8e-11
Identities = 59/223 (26%), Positives = 90/223 (40%), Gaps = 5/223 (2%)
Query: 71 IDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS 129
+D S + VP L ++ Q L L+ N + I S LK L++L L +N++ +
Sbjct: 41 VDCSGKGLTAVPEG--LSAFT-QALQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVP 97
Query: 130 DNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRN 189
A D N + ++P F L L L L +N+L + +L L+
Sbjct: 98 SEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPTLQA 157
Query: 190 LDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVH 249
L L N +S IPD F++ +L L L NK+R ++ F G E
Sbjct: 158 LTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFP 217
Query: 250 FKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNP 292
+A L +L L N +P D P L + L NP
Sbjct: 218 -QAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNP 259
Score = 44.0 bits (99), Expect = 0.006
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 2/114 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ LP F L+ + LQRN + +I F L +DLS N ++ + + FA
Sbjct: 329 NNIRDLPS--FNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFA 386
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQI 117
+ +D+S N + P++ GL L+++ K K +L++L +
Sbjct: 387 TLGPITNLDVSFNELTSFPTEGLNGLNQLKLVGNFKLKEALAAKDFVNLRSLSV 440
>BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 106 bits (255), Expect = 7e-22
Identities = 74/244 (30%), Positives = 112/244 (45%), Gaps = 2/244 (0%)
Query: 48 DLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ- 106
DLS N L L LF + FLE + +S N + ++P +F GLYSL+IL L N++ I
Sbjct: 20 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 79
Query: 107 NGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFL 166
+ L +LQ L+L N I+ + + +FE D N L IP + NNL L +
Sbjct: 80 EALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 139
Query: 167 DLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINI 226
L+ N + + F++L L L L N + + ++F NLE LDL+ NKL+ +
Sbjct: 140 TLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPV 199
Query: 227 TAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIV 286
A + KAF L T++ N + Y+PKL +
Sbjct: 200 -AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTL 258
Query: 287 KLSG 290
L+G
Sbjct: 259 SLNG 262
Score = 100 bits (239), Expect = 6e-20
Identities = 80/289 (27%), Positives = 127/289 (43%), Gaps = 3/289 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ L G+F L L+ LRL N+L I +AF+ L + L NN L +P +
Sbjct: 24 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 83
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ-NGTFSLKNLQILKLSD 122
L+++ + N + VP SF GL SL+ L L N + I +L LQ + L+
Sbjct: 84 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 143
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I++I D AF+N N+++++ T F L L LDL+ N L V
Sbjct: 144 NRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFP-VAIR 202
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
+L L+ L N + IP+ F L+ + N ++F+ +AF
Sbjct: 203 TLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG 262
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ F +L L L LPS +P+L +++LS N
Sbjct: 263 AMDIQ-EFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHN 310
Score = 97.5 bits (232), Expect = 5e-19
Identities = 77/257 (29%), Positives = 109/257 (42%), Gaps = 6/257 (2%)
Query: 25 LQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSD 84
L N L E+ F + L + LS N+L +P + F+ L+ + + NN++ +P++
Sbjct: 21 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 80
Query: 85 SFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXX 143
+ L SLQ L L N I + +F L +L+ L L DN + I A N
Sbjct: 81 ALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMT 140
Query: 144 XDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDN 203
N++ +IP F NL L+ L L NN + L FE L L LDL N L + P
Sbjct: 141 LALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFP-V 199
Query: 204 TFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLY 263
L++L N ++ I AF G V AF L L TL
Sbjct: 200 AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLS 259
Query: 264 LDGNM----FPSLPSRT 276
L+G M FP L T
Sbjct: 260 LNGAMDIQEFPDLKGTT 276
Score = 87.8 bits (208), Expect = 4e-16
Identities = 84/311 (27%), Positives = 130/311 (41%), Gaps = 28/311 (9%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + +P FE L +L+ L L N L EI A + L + L+ N + +P+ F
Sbjct: 96 NLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQ 155
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
N T L + + NNR+ ++ + SF GL++L+ LDL+ NK+Q +L LQ L +N
Sbjct: 156 NLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNN 215
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLI------------FLDLSNN 171
I I + AF N ++ + F L L F DL
Sbjct: 216 NIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGT 275
Query: 172 NLMSL-----AGVEF------ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
+ + AG+ + L LR L+L N + ++P + C LE++ L N+
Sbjct: 276 TSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP--SLHRCQKLEEIGLQHNR 333
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ I F +H +AFS L +L L L N +LP L +
Sbjct: 334 IWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP---LAGL 390
Query: 281 PKLTIVKLSGN 291
L +KL GN
Sbjct: 391 GGLMHLKLKGN 401
Score = 82.6 bits (195), Expect = 1e-14
Identities = 64/233 (27%), Positives = 105/233 (45%), Gaps = 7/233 (3%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N +++L FE L NL+TL L N L+E A + +L + NN + +PEK
Sbjct: 165 LHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPV-AIRTLGRLQELGFHNNNIKAIPEK 223
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQN--GTFSLKNLQIL 118
F N L+TI +N + +V +F L L L L N +IQ +L+IL
Sbjct: 224 AFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSL--NGAMDIQEFPDLKGTTSLEIL 281
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
L+ I + + N+++ +P+ + + L + L +N + +
Sbjct: 282 TLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGA 339
Query: 179 VEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
F L L+ LDL NA+ I FS +L KLDL+ N+L + + G
Sbjct: 340 DTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGG 392
Score = 74.9 bits (176), Expect = 3e-12
Identities = 57/224 (25%), Positives = 100/224 (44%), Gaps = 5/224 (2%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + +P L +L++LRL N + + +F L H+ L +N L +P +
Sbjct: 71 NNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRAL 130
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
N L+ + ++ NR+ ++P +F L SL +L L N+IQ++ +F L NL+ L L+
Sbjct: 131 NNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLN 190
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
NK+ A N +K IP + F L + +N + + F
Sbjct: 191 YNKLQEF-PVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAF 249
Query: 182 ESLKLLRNLDLK-ENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ L L L L + + PD +LE L L++ +R +
Sbjct: 250 QYLPKLHTLSLNGAMDIQEFPD--LKGTTSLEILTLTRAGIRLL 291
>AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor
protein.
Length = 915
Score = 106 bits (255), Expect = 7e-22
Identities = 74/244 (30%), Positives = 112/244 (45%), Gaps = 2/244 (0%)
Query: 48 DLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ- 106
DLS N L L LF + FLE + +S N + ++P +F GLYSL+IL L N++ I
Sbjct: 20 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 79
Query: 107 NGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFL 166
+ L +LQ L+L N I+ + + +FE D N L IP + NNL L +
Sbjct: 80 EALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 139
Query: 167 DLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINI 226
L+ N + + F++L L L L N + + ++F NLE LDL+ NKL+ +
Sbjct: 140 TLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPV 199
Query: 227 TAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIV 286
A + KAF L T++ N + Y+PKL +
Sbjct: 200 -AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTL 258
Query: 287 KLSG 290
L+G
Sbjct: 259 SLNG 262
Score = 100 bits (239), Expect = 6e-20
Identities = 80/289 (27%), Positives = 127/289 (43%), Gaps = 3/289 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ L G+F L L+ LRL N+L I +AF+ L + L NN L +P +
Sbjct: 24 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 83
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ-NGTFSLKNLQILKLSD 122
L+++ + N + VP SF GL SL+ L L N + I +L LQ + L+
Sbjct: 84 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 143
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I++I D AF+N N+++++ T F L L LDL+ N L V
Sbjct: 144 NRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFP-VAIR 202
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
+L L+ L N + IP+ F L+ + N ++F+ +AF
Sbjct: 203 TLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG 262
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ F +L L L LPS +P+L +++LS N
Sbjct: 263 AMDIQ-EFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHN 310
Score = 97.5 bits (232), Expect = 5e-19
Identities = 77/257 (29%), Positives = 109/257 (42%), Gaps = 6/257 (2%)
Query: 25 LQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSD 84
L N L E+ F + L + LS N+L +P + F+ L+ + + NN++ +P++
Sbjct: 21 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 80
Query: 85 SFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXX 143
+ L SLQ L L N I + +F L +L+ L L DN + I A N
Sbjct: 81 ALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMT 140
Query: 144 XDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDN 203
N++ +IP F NL L+ L L NN + L FE L L LDL N L + P
Sbjct: 141 LALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFP-V 199
Query: 204 TFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLY 263
L++L N ++ I AF G V AF L L TL
Sbjct: 200 AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLS 259
Query: 264 LDGNM----FPSLPSRT 276
L+G M FP L T
Sbjct: 260 LNGAMDIQEFPDLKGTT 276
Score = 87.8 bits (208), Expect = 4e-16
Identities = 84/311 (27%), Positives = 130/311 (41%), Gaps = 28/311 (9%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + +P FE L +L+ L L N L EI A + L + L+ N + +P+ F
Sbjct: 96 NLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQ 155
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
N T L + + NNR+ ++ + SF GL++L+ LDL+ NK+Q +L LQ L +N
Sbjct: 156 NLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNN 215
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLI------------FLDLSNN 171
I I + AF N ++ + F L L F DL
Sbjct: 216 NIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGT 275
Query: 172 NLMSL-----AGVEF------ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
+ + AG+ + L LR L+L N + ++P + C LE++ L N+
Sbjct: 276 TSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP--SLHRCQKLEEIGLQHNR 333
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ I F +H +AFS L +L L L N +LP L +
Sbjct: 334 IWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP---LAGL 390
Query: 281 PKLTIVKLSGN 291
L +KL GN
Sbjct: 391 GGLMHLKLKGN 401
Score = 82.6 bits (195), Expect = 1e-14
Identities = 64/233 (27%), Positives = 105/233 (45%), Gaps = 7/233 (3%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N +++L FE L NL+TL L N L+E A + +L + NN + +PEK
Sbjct: 165 LHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPV-AIRTLGRLQELGFHNNNIKAIPEK 223
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQN--GTFSLKNLQIL 118
F N L+TI +N + +V +F L L L L N +IQ +L+IL
Sbjct: 224 AFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSL--NGAMDIQEFPDLKGTTSLEIL 281
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
L+ I + + N+++ +P+ + + L + L +N + +
Sbjct: 282 TLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGA 339
Query: 179 VEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
F L L+ LDL NA+ I FS +L KLDL+ N+L + + G
Sbjct: 340 DTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGG 392
Score = 74.9 bits (176), Expect = 3e-12
Identities = 57/224 (25%), Positives = 100/224 (44%), Gaps = 5/224 (2%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + +P L +L++LRL N + + +F L H+ L +N L +P +
Sbjct: 71 NNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRAL 130
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
N L+ + ++ NR+ ++P +F L SL +L L N+IQ++ +F L NL+ L L+
Sbjct: 131 NNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLN 190
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
NK+ A N +K IP + F L + +N + + F
Sbjct: 191 YNKLQEF-PVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAF 249
Query: 182 ESLKLLRNLDLK-ENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ L L L L + + PD +LE L L++ +R +
Sbjct: 250 QYLPKLHTLSLNGAMDIQEFPD--LKGTTSLEILTLTRAGIRLL 291
>AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 106 bits (255), Expect = 7e-22
Identities = 74/244 (30%), Positives = 112/244 (45%), Gaps = 2/244 (0%)
Query: 48 DLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ- 106
DLS N L L LF + FLE + +S N + ++P +F GLYSL+IL L N++ I
Sbjct: 20 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 79
Query: 107 NGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFL 166
+ L +LQ L+L N I+ + + +FE D N L IP + NNL L +
Sbjct: 80 EALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 139
Query: 167 DLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINI 226
L+ N + + F++L L L L N + + ++F NLE LDL+ NKL+ +
Sbjct: 140 TLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPV 199
Query: 227 TAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIV 286
A + KAF L T++ N + Y+PKL +
Sbjct: 200 -AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTL 258
Query: 287 KLSG 290
L+G
Sbjct: 259 SLNG 262
Score = 100 bits (239), Expect = 6e-20
Identities = 80/289 (27%), Positives = 127/289 (43%), Gaps = 3/289 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ L G+F L L+ LRL N+L I +AF+ L + L NN L +P +
Sbjct: 24 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 83
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ-NGTFSLKNLQILKLSD 122
L+++ + N + VP SF GL SL+ L L N + I +L LQ + L+
Sbjct: 84 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 143
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I++I D AF+N N+++++ T F L L LDL+ N L V
Sbjct: 144 NRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFP-VAIR 202
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
+L L+ L N + IP+ F L+ + N ++F+ +AF
Sbjct: 203 TLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG 262
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ F +L L L LPS +P+L +++LS N
Sbjct: 263 AMDIQ-EFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHN 310
Score = 97.5 bits (232), Expect = 5e-19
Identities = 77/257 (29%), Positives = 109/257 (42%), Gaps = 6/257 (2%)
Query: 25 LQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSD 84
L N L E+ F + L + LS N+L +P + F+ L+ + + NN++ +P++
Sbjct: 21 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 80
Query: 85 SFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXX 143
+ L SLQ L L N I + +F L +L+ L L DN + I A N
Sbjct: 81 ALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMT 140
Query: 144 XDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDN 203
N++ +IP F NL L+ L L NN + L FE L L LDL N L + P
Sbjct: 141 LALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFP-V 199
Query: 204 TFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLY 263
L++L N ++ I AF G V AF L L TL
Sbjct: 200 AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLS 259
Query: 264 LDGNM----FPSLPSRT 276
L+G M FP L T
Sbjct: 260 LNGAMDIQEFPDLKGTT 276
Score = 87.8 bits (208), Expect = 4e-16
Identities = 84/311 (27%), Positives = 130/311 (41%), Gaps = 28/311 (9%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + +P FE L +L+ L L N L EI A + L + L+ N + +P+ F
Sbjct: 96 NLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQ 155
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
N T L + + NNR+ ++ + SF GL++L+ LDL+ NK+Q +L LQ L +N
Sbjct: 156 NLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNN 215
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLI------------FLDLSNN 171
I I + AF N ++ + F L L F DL
Sbjct: 216 NIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGT 275
Query: 172 NLMSL-----AGVEF------ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
+ + AG+ + L LR L+L N + ++P + C LE++ L N+
Sbjct: 276 TSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP--SLHRCQKLEEIGLQHNR 333
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ I F +H +AFS L +L L L N +LP L +
Sbjct: 334 IWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP---LAGL 390
Query: 281 PKLTIVKLSGN 291
L +KL GN
Sbjct: 391 GGLMHLKLKGN 401
Score = 82.6 bits (195), Expect = 1e-14
Identities = 64/233 (27%), Positives = 105/233 (45%), Gaps = 7/233 (3%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N +++L FE L NL+TL L N L+E A + +L + NN + +PEK
Sbjct: 165 LHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPV-AIRTLGRLQELGFHNNNIKAIPEK 223
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQN--GTFSLKNLQIL 118
F N L+TI +N + +V +F L L L L N +IQ +L+IL
Sbjct: 224 AFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSL--NGAMDIQEFPDLKGTTSLEIL 281
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
L+ I + + N+++ +P+ + + L + L +N + +
Sbjct: 282 TLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGA 339
Query: 179 VEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
F L L+ LDL NA+ I FS +L KLDL+ N+L + + G
Sbjct: 340 DTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGG 392
Score = 74.9 bits (176), Expect = 3e-12
Identities = 57/224 (25%), Positives = 100/224 (44%), Gaps = 5/224 (2%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + +P L +L++LRL N + + +F L H+ L +N L +P +
Sbjct: 71 NNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRAL 130
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
N L+ + ++ NR+ ++P +F L SL +L L N+IQ++ +F L NL+ L L+
Sbjct: 131 NNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLN 190
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
NK+ A N +K IP + F L + +N + + F
Sbjct: 191 YNKLQEF-PVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAF 249
Query: 182 ESLKLLRNLDLK-ENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ L L L L + + PD +LE L L++ +R +
Sbjct: 250 QYLPKLHTLSLNGAMDIQEFPD--LKGTTSLEILTLTRAGIRLL 291
>BC111745-1|AAI11746.1| 653|Homo sapiens leucine rich repeat
containing 4 protein.
Length = 653
Score = 105 bits (253), Expect = 1e-21
Identities = 77/280 (27%), Positives = 129/280 (46%), Gaps = 7/280 (2%)
Query: 54 LYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-L 112
L +P+ + +N +L ++ N + + +D+F L+ L++L L +N I+ I+ G F+ L
Sbjct: 66 LSEVPQGIPSNTRYLNLME---NNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGL 122
Query: 113 KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSN-N 171
+L L+L DN + I AFE N +++IP+ FN + L+ LDL
Sbjct: 123 ASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELK 182
Query: 172 NLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
L ++ FE L L+ L+L + +P+ T LE+L++S N I +F+G
Sbjct: 183 KLEYISEGAFEGLFNLKYLNLGMCNIKDMPNLT--PLVGLEELEMSGNHFPEIRPGSFHG 240
Query: 232 XXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ AF L +L L L N SLP + L + L N
Sbjct: 241 LSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHN 300
Query: 292 PWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFL 331
PW+CDC L+++ W+R C +P ++ G +L
Sbjct: 301 PWNCDCDILWLAWWLREYIPTNSTCCGRCHAPMHMRGRYL 340
Score = 72.9 bits (171), Expect = 1e-11
Identities = 59/221 (26%), Positives = 101/221 (45%), Gaps = 4/221 (1%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N+++ + F L +L+ L+L RN + +I+ AF L ++L +N+L +P
Sbjct: 82 LMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSG 141
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSK-NKIQNIQNGTF-SLKNLQIL 118
F + L + + NN + +PS +F + SL LDL + K++ I G F L NL+ L
Sbjct: 142 AFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYL 201
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
L I ++ + N I F+ L L L + N+ + +
Sbjct: 202 NLGMCNIKDMPN--LTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIER 259
Query: 179 VEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
F+ L L L+L N LS +P + F+ L +L L N
Sbjct: 260 NAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHN 300
>BC111561-1|AAI11562.1| 653|Homo sapiens leucine rich repeat
containing 4 protein.
Length = 653
Score = 105 bits (253), Expect = 1e-21
Identities = 77/280 (27%), Positives = 129/280 (46%), Gaps = 7/280 (2%)
Query: 54 LYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-L 112
L +P+ + +N +L ++ N + + +D+F L+ L++L L +N I+ I+ G F+ L
Sbjct: 66 LSEVPQGIPSNTRYLNLME---NNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGL 122
Query: 113 KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSN-N 171
+L L+L DN + I AFE N +++IP+ FN + L+ LDL
Sbjct: 123 ASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELK 182
Query: 172 NLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
L ++ FE L L+ L+L + +P+ T LE+L++S N I +F+G
Sbjct: 183 KLEYISEGAFEGLFNLKYLNLGMCNIKDMPNLT--PLVGLEELEMSGNHFPEIRPGSFHG 240
Query: 232 XXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ AF L +L L L N SLP + L + L N
Sbjct: 241 LSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHN 300
Query: 292 PWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFL 331
PW+CDC L+++ W+R C +P ++ G +L
Sbjct: 301 PWNCDCDILWLAWWLREYIPTNSTCCGRCHAPMHMRGRYL 340
Score = 72.9 bits (171), Expect = 1e-11
Identities = 59/221 (26%), Positives = 101/221 (45%), Gaps = 4/221 (1%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N+++ + F L +L+ L+L RN + +I+ AF L ++L +N+L +P
Sbjct: 82 LMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSG 141
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSK-NKIQNIQNGTF-SLKNLQIL 118
F + L + + NN + +PS +F + SL LDL + K++ I G F L NL+ L
Sbjct: 142 AFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYL 201
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
L I ++ + N I F+ L L L + N+ + +
Sbjct: 202 NLGMCNIKDMPN--LTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIER 259
Query: 179 VEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
F+ L L L+L N LS +P + F+ L +L L N
Sbjct: 260 NAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHN 300
>AY358307-1|AAQ88674.1| 653|Homo sapiens NAG14 protein.
Length = 653
Score = 105 bits (253), Expect = 1e-21
Identities = 77/280 (27%), Positives = 129/280 (46%), Gaps = 7/280 (2%)
Query: 54 LYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-L 112
L +P+ + +N +L ++ N + + +D+F L+ L++L L +N I+ I+ G F+ L
Sbjct: 66 LSEVPQGIPSNTRYLNLME---NNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGL 122
Query: 113 KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSN-N 171
+L L+L DN + I AFE N +++IP+ FN + L+ LDL
Sbjct: 123 ASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELK 182
Query: 172 NLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
L ++ FE L L+ L+L + +P+ T LE+L++S N I +F+G
Sbjct: 183 KLEYISEGAFEGLFNLKYLNLGMCNIKDMPNLT--PLVGLEELEMSGNHFPEIRPGSFHG 240
Query: 232 XXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ AF L +L L L N SLP + L + L N
Sbjct: 241 LSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHN 300
Query: 292 PWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFL 331
PW+CDC L+++ W+R C +P ++ G +L
Sbjct: 301 PWNCDCDILWLAWWLREYIPTNSTCCGRCHAPMHMRGRYL 340
Score = 72.9 bits (171), Expect = 1e-11
Identities = 59/221 (26%), Positives = 101/221 (45%), Gaps = 4/221 (1%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N+++ + F L +L+ L+L RN + +I+ AF L ++L +N+L +P
Sbjct: 82 LMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSG 141
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSK-NKIQNIQNGTF-SLKNLQIL 118
F + L + + NN + +PS +F + SL LDL + K++ I G F L NL+ L
Sbjct: 142 AFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYL 201
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
L I ++ + N I F+ L L L + N+ + +
Sbjct: 202 NLGMCNIKDMPN--LTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIER 259
Query: 179 VEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
F+ L L L+L N LS +P + F+ L +L L N
Sbjct: 260 NAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHN 300
>AY182024-1|AAO67545.1| 522|Homo sapiens leucine-rich repeat
transmembrane neuronal 1 protein protein.
Length = 522
Score = 105 bits (253), Expect = 1e-21
Identities = 82/303 (27%), Positives = 135/303 (44%), Gaps = 6/303 (1%)
Query: 29 YLEEID-SEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFL 87
Y E ++ +EA + L + L N L L F L + + +N + V D+F
Sbjct: 51 YCEALNLTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQ 110
Query: 88 GLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDR 146
L ++ L LS N+I + N TF + NL+ + LS NK+ ++ + F
Sbjct: 111 KLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRA 170
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N ++ +P ++F + + L FLD+ N L SLA F L L L L+ N L ++ F
Sbjct: 171 NAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFP 230
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXY-EVHFKAFSMLKNLTTLYLD 265
+L L L +NK+ + + + Y E H F + +L +L LD
Sbjct: 231 RLISLHSLCLRRNKVAIVVSSLDWVWNLEKMDLSGNEIEYMEPH--VFETVPHLQSLQLD 288
Query: 266 GNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWY 325
N + R L+ LT + L+GN W C + +++W+ N +D + C SP Y
Sbjct: 289 SNRLTYIEPRILNSWKSLTSITLAGNLWDCGRNVCALASWLN-NFQGRYDGNLQCASPEY 347
Query: 326 LEG 328
+G
Sbjct: 348 AQG 350
Score = 79.0 bits (186), Expect = 2e-13
Identities = 55/222 (24%), Positives = 100/222 (45%), Gaps = 2/222 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L G F L+ L L L N++ + +AF +++ + LS+N + LP F
Sbjct: 75 NSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFR 134
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L ++D+S N++ + D F GL L L + N IQ + F ++L+ L +
Sbjct: 135 PMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGY 194
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N++ +++ N+F + N L + F L L L L N +++ +
Sbjct: 195 NQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNK-VAIVVSSLD 253
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ L +DL N + + + F +L+ L L N+L +I
Sbjct: 254 WVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLTYI 295
Score = 75.4 bits (177), Expect = 2e-12
Identities = 58/217 (26%), Positives = 99/217 (45%), Gaps = 2/217 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ + G F+ L +K L L N + ++ + F L VDLS N L L LF
Sbjct: 99 NHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFH 158
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L T+ + N + +VP F SL+ LD+ N+++++ +F+ L L L L
Sbjct: 159 GLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEH 218
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + ++ F RNK+ + + L + + L +DLS N + + FE
Sbjct: 219 NDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSL-DWVWNLEKMDLSGNEIEYMEPHVFE 277
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
++ L++L L N L+ I + +L + L+ N
Sbjct: 278 TVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
>AK056644-1|BAB71240.1| 522|Homo sapiens protein ( Homo sapiens
cDNA FLJ32082 fis, clone OCBBF2000231, weakly similar to
PHOSPHOLIPASE A2 INHIBITOR SUBUNIT B PRECURSOR. ).
Length = 522
Score = 105 bits (253), Expect = 1e-21
Identities = 82/303 (27%), Positives = 135/303 (44%), Gaps = 6/303 (1%)
Query: 29 YLEEID-SEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFL 87
Y E ++ +EA + L + L N L L F L + + +N + V D+F
Sbjct: 51 YCEALNLTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQ 110
Query: 88 GLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDR 146
L ++ L LS N+I + N TF + NL+ + LS NK+ ++ + F
Sbjct: 111 KLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRA 170
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N ++ +P ++F + + L FLD+ N L SLA F L L L L+ N L ++ F
Sbjct: 171 NAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFP 230
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXY-EVHFKAFSMLKNLTTLYLD 265
+L L L +NK+ + + + Y E H F + +L +L LD
Sbjct: 231 RLISLHSLCLRRNKVAIVVSSLDWVWNLEKMDLSGNEIEYMEPH--VFETVPHLQSLQLD 288
Query: 266 GNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWY 325
N + R L+ LT + L+GN W C + +++W+ N +D + C SP Y
Sbjct: 289 SNRLTYIEPRILNSWKSLTSITLAGNLWDCGRNVCALASWLN-NFQGRYDGNLQCASPEY 347
Query: 326 LEG 328
+G
Sbjct: 348 AQG 350
Score = 79.0 bits (186), Expect = 2e-13
Identities = 55/222 (24%), Positives = 100/222 (45%), Gaps = 2/222 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L G F L+ L L L N++ + +AF +++ + LS+N + LP F
Sbjct: 75 NSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFR 134
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L ++D+S N++ + D F GL L L + N IQ + F ++L+ L +
Sbjct: 135 PMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGY 194
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N++ +++ N+F + N L + F L L L L N +++ +
Sbjct: 195 NQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNK-VAIVVSSLD 253
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ L +DL N + + + F +L+ L L N+L +I
Sbjct: 254 WVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLTYI 295
Score = 75.4 bits (177), Expect = 2e-12
Identities = 58/217 (26%), Positives = 99/217 (45%), Gaps = 2/217 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ + G F+ L +K L L N + ++ + F L VDLS N L L LF
Sbjct: 99 NHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFH 158
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L T+ + N + +VP F SL+ LD+ N+++++ +F+ L L L L
Sbjct: 159 GLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEH 218
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + ++ F RNK+ + + L + + L +DLS N + + FE
Sbjct: 219 NDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSL-DWVWNLEKMDLSGNEIEYMEPHVFE 277
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
++ L++L L N L+ I + +L + L+ N
Sbjct: 278 TVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
>AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein
LRIG1 protein.
Length = 1093
Score = 105 bits (253), Expect = 1e-21
Identities = 74/273 (27%), Positives = 123/273 (45%), Gaps = 4/273 (1%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
++L L N L EID F L V L+NN L +P L A ++ + ++ + +N++
Sbjct: 71 RSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPS-LGAASSHVVSLFLQHNKIRS 129
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTFSL-KNLQILKLSDNKINNISDNAFENXXXX 139
V SL++LDLS N I ++N F ++ L L+ N+I + AF+
Sbjct: 130 VEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRS 189
Query: 140 XXXXX-DRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALS 198
+N++ +P + F L L LDL+ N + + G+ F+ L L L L+ N +S
Sbjct: 190 LLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNIS 248
Query: 199 QIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKN 258
++ D F + L L N L +N + YG +H K +S +
Sbjct: 249 KLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQK 308
Query: 259 LTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L L L N L +L + L++++LS N
Sbjct: 309 LHELVLSFNNLTRLDEESLAELSSLSVLRLSHN 341
Score = 99.1 bits (236), Expect = 1e-19
Identities = 84/314 (26%), Positives = 134/314 (42%), Gaps = 7/314 (2%)
Query: 20 LKTLRLQRNYLEEIDSEAFTS-TKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
+K L L N + ++ AF ++ L + LS N + LP + F L +D++ NR+
Sbjct: 165 IKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFKLPR-LTQLDLNRNRI 223
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXX 137
+ +F GL SL++L L +N I + +G F L + +L L N + ++ +
Sbjct: 224 RLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLT 283
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
N + I + ++ + L L LS NNL L L L L L N++
Sbjct: 284 ALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSI 343
Query: 198 SQIPDNTFSDCFNLEKLDLSKNKLR-FINIT--AFYGXXXXXXXXXXXXXXYEVHFKAFS 254
S I + F +L LDL N++ I T AF G V +AFS
Sbjct: 344 SHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFS 403
Query: 255 MLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIW 314
L+ L L L GN S+ M L + +S + + CDC ++ W+ + M
Sbjct: 404 GLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHISSDSFLCDCQLKWLPPWL-IGRMLQA 462
Query: 315 DYSPTCVSPWYLEG 328
+ TC P L+G
Sbjct: 463 FVTATCAHPESLKG 476
Score = 98.3 bits (234), Expect = 3e-19
Identities = 75/271 (27%), Positives = 120/271 (44%), Gaps = 6/271 (2%)
Query: 4 NHVEYLPGGIFESLV-NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
N + L G F+ L +L TLRL +N + ++ AF +L +DL+ N + + F
Sbjct: 173 NRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAF-KLPRLTQLDLNRNRIRLIEGLTF 231
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT-FSLKNLQILKLS 121
LE + + N + + +F GL + +L L N + + +G+ + L L L LS
Sbjct: 232 QGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLS 291
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
+N I I + N L + + L L L LS+N++ +A F
Sbjct: 292 NNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAF 351
Query: 182 ESLKLLRNLDLKENALSQIPDNT---FSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXX 238
+ L+ LR LDL N +S ++T FS +L KL L NK++ + AF G
Sbjct: 352 KGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHL 411
Query: 239 XXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
V F AF +KNL L++ + F
Sbjct: 412 NLGGNAIRSVQFDAFVKMKNLKELHISSDSF 442
>AF196976-1|AAG28019.2| 653|Homo sapiens brain tumor associated
protein LRRC4 protein.
Length = 653
Score = 105 bits (253), Expect = 1e-21
Identities = 77/280 (27%), Positives = 129/280 (46%), Gaps = 7/280 (2%)
Query: 54 LYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-L 112
L +P+ + +N +L ++ N + + +D+F L+ L++L L +N I+ I+ G F+ L
Sbjct: 66 LSEVPQGIPSNTRYLNLME---NNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGL 122
Query: 113 KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSN-N 171
+L L+L DN + I AFE N +++IP+ FN + L+ LDL
Sbjct: 123 ASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELK 182
Query: 172 NLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
L ++ FE L L+ L+L + +P+ T LE+L++S N I +F+G
Sbjct: 183 KLEYISEGAFEGLFNLKYLNLGMCNIKDMPNLT--PLVGLEELEMSGNHFPEIRPGSFHG 240
Query: 232 XXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ AF L +L L L N SLP + L + L N
Sbjct: 241 LSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHN 300
Query: 292 PWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFL 331
PW+CDC L+++ W+R C +P ++ G +L
Sbjct: 301 PWNCDCDILWLAWWLREYIPTNSTCCGRCHAPMHMRGRYL 340
Score = 72.9 bits (171), Expect = 1e-11
Identities = 59/221 (26%), Positives = 101/221 (45%), Gaps = 4/221 (1%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N+++ + F L +L+ L+L RN + +I+ AF L ++L +N+L +P
Sbjct: 82 LMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSG 141
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSK-NKIQNIQNGTF-SLKNLQIL 118
F + L + + NN + +PS +F + SL LDL + K++ I G F L NL+ L
Sbjct: 142 AFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYL 201
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
L I ++ + N I F+ L L L + N+ + +
Sbjct: 202 NLGMCNIKDMPN--LTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIER 259
Query: 179 VEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
F+ L L L+L N LS +P + F+ L +L L N
Sbjct: 260 NAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHN 300
>AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein
LIG-1 protein.
Length = 1094
Score = 105 bits (253), Expect = 1e-21
Identities = 74/273 (27%), Positives = 123/273 (45%), Gaps = 4/273 (1%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
++L L N L EID F L V L+NN L +P L A ++ + ++ + +N++
Sbjct: 71 RSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPS-LGAASSHVVSLFLQHNKIRS 129
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTFSL-KNLQILKLSDNKINNISDNAFENXXXX 139
V SL++LDLS N I ++N F ++ L L+ N+I + AF+
Sbjct: 130 VEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRS 189
Query: 140 XXXXX-DRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALS 198
+N++ +P + F L L LDL+ N + + G+ F+ L L L L+ N +S
Sbjct: 190 LLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNIS 248
Query: 199 QIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKN 258
++ D F + L L N L +N + YG +H K +S +
Sbjct: 249 KLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQK 308
Query: 259 LTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L L L N L +L + L++++LS N
Sbjct: 309 LHELVLSFNNLTRLDEESLAELSSLSVLRLSHN 341
Score = 99.1 bits (236), Expect = 1e-19
Identities = 84/314 (26%), Positives = 134/314 (42%), Gaps = 7/314 (2%)
Query: 20 LKTLRLQRNYLEEIDSEAFTS-TKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
+K L L N + ++ AF ++ L + LS N + LP + F L +D++ NR+
Sbjct: 165 IKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFKLPR-LTQLDLNRNRI 223
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXX 137
+ +F GL SL++L L +N I + +G F L + +L L N + ++ +
Sbjct: 224 RLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLT 283
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
N + I + ++ + L L LS NNL L L L L L N++
Sbjct: 284 ALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSI 343
Query: 198 SQIPDNTFSDCFNLEKLDLSKNKLR-FINIT--AFYGXXXXXXXXXXXXXXYEVHFKAFS 254
S I + F +L LDL N++ I T AF G V +AFS
Sbjct: 344 SHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFS 403
Query: 255 MLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIW 314
L+ L L L GN S+ M L + +S + + CDC ++ W+ + M
Sbjct: 404 GLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHISSDSFLCDCQLKWLPPWL-IGRMLQA 462
Query: 315 DYSPTCVSPWYLEG 328
+ TC P L+G
Sbjct: 463 FVTATCAHPESLKG 476
Score = 98.3 bits (234), Expect = 3e-19
Identities = 75/271 (27%), Positives = 120/271 (44%), Gaps = 6/271 (2%)
Query: 4 NHVEYLPGGIFESLV-NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
N + L G F+ L +L TLRL +N + ++ AF +L +DL+ N + + F
Sbjct: 173 NRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAF-KLPRLTQLDLNRNRIRLIEGLTF 231
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT-FSLKNLQILKLS 121
LE + + N + + +F GL + +L L N + + +G+ + L L L LS
Sbjct: 232 QGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLS 291
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
+N I I + N L + + L L L LS+N++ +A F
Sbjct: 292 NNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAF 351
Query: 182 ESLKLLRNLDLKENALSQIPDNT---FSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXX 238
+ L+ LR LDL N +S ++T FS +L KL L NK++ + AF G
Sbjct: 352 KGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHL 411
Query: 239 XXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
V F AF +KNL L++ + F
Sbjct: 412 NLGGNAIRSVQFDAFVKMKNLKELHISSDSF 442
>BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 105 bits (252), Expect = 2e-21
Identities = 82/316 (25%), Positives = 139/316 (43%), Gaps = 8/316 (2%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTS-TKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNN 76
+ LK L L N + +++ F + + L V L+ N + +P K+F L+ +++ N
Sbjct: 167 MQLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIF-KLPHLQFLELKRN 225
Query: 77 RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFEN 135
R+ V +F GL SL+ L + +N I +++G F L N++ L+L N + ++
Sbjct: 226 RIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYG 285
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
+N ++ I + + L LDLS N L L F L LL L+L +N
Sbjct: 286 LRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDN 345
Query: 196 ALSQIPDNTFSDCFNLEKLDLSKNKLRFI---NITAFYGXXXXXXXXXXXXXXYEVHFKA 252
++ I D F NL+ LDL N++ + AF G + KA
Sbjct: 346 RVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKA 405
Query: 253 FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMK 312
F L++L L L+ N S+ L + L+ + CDCH ++ W+ N +
Sbjct: 406 FIGLESLEHLDLNNNAIMSIQENAFS-QTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQ 464
Query: 313 IWDYSPTCVSPWYLEG 328
+ +C P +L G
Sbjct: 465 -HSVNVSCAHPEWLAG 479
Score = 97.1 bits (231), Expect = 6e-19
Identities = 69/254 (27%), Positives = 117/254 (46%), Gaps = 2/254 (0%)
Query: 15 ESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDIS 74
E N+ L L N + EI+++A L +DLS+N + + F L+ +++S
Sbjct: 117 EPTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQ-LKYLNLS 175
Query: 75 NNRVVYVPSDSFLGLYS-LQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAF 133
NNR+ + + F L S L ++ L++N++ I F L +LQ L+L N+I + F
Sbjct: 176 NNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTF 235
Query: 134 ENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLK 193
+ RN + + F L + L+L +NNL + L++L+ L +
Sbjct: 236 QGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVS 295
Query: 194 ENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAF 253
+NA+ +I + + C L +LDLS N+L ++ +AF G + F
Sbjct: 296 QNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVF 355
Query: 254 SMLKNLTTLYLDGN 267
L NL TL L N
Sbjct: 356 RFLSNLQTLDLRNN 369
Score = 76.6 bits (180), Expect = 9e-13
Identities = 58/198 (29%), Positives = 97/198 (48%), Gaps = 5/198 (2%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L G F L N++ L L+ N L ++ + L + +S N + + +
Sbjct: 249 NGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWE 308
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L +D+S N++ + +F+GL L+ L+L N++ +I +G F L NLQ L L +
Sbjct: 309 FCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRN 368
Query: 123 NKIN-NISD--NAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
N+I+ I D AF N++K+I + F L+ L LDL+NN +MS+
Sbjct: 369 NEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQEN 428
Query: 180 EFESLKLLRNLDLKENAL 197
F S L+ L L ++L
Sbjct: 429 AF-SQTHLKELILNTSSL 445
Score = 51.6 bits (118), Expect = 3e-05
Identities = 28/87 (32%), Positives = 47/87 (54%), Gaps = 3/87 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLE---EIDSEAFTSTKKLFHVDLSNNYLYTLPE 59
DN V ++ G+F L NL+TL L+ N + E SEAF L + L N + ++ +
Sbjct: 344 DNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITK 403
Query: 60 KLFANNTFLETIDISNNRVVYVPSDSF 86
K F LE +D++NN ++ + ++F
Sbjct: 404 KAFIGLESLEHLDLNNNAIMSIQENAF 430
>BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 105 bits (252), Expect = 2e-21
Identities = 82/316 (25%), Positives = 139/316 (43%), Gaps = 8/316 (2%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTS-TKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNN 76
+ LK L L N + +++ F + + L V L+ N + +P K+F L+ +++ N
Sbjct: 167 MQLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIF-KLPHLQFLELKRN 225
Query: 77 RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFEN 135
R+ V +F GL SL+ L + +N I +++G F L N++ L+L N + ++
Sbjct: 226 RIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYG 285
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
+N ++ I + + L LDLS N L L F L LL L+L +N
Sbjct: 286 LRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDN 345
Query: 196 ALSQIPDNTFSDCFNLEKLDLSKNKLRFI---NITAFYGXXXXXXXXXXXXXXYEVHFKA 252
++ I D F NL+ LDL N++ + AF G + KA
Sbjct: 346 RVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKA 405
Query: 253 FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMK 312
F L++L L L+ N S+ L + L+ + CDCH ++ W+ N +
Sbjct: 406 FIGLESLEHLDLNNNAIMSIQENAFS-QTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQ 464
Query: 313 IWDYSPTCVSPWYLEG 328
+ +C P +L G
Sbjct: 465 -HSVNVSCAHPEWLAG 479
Score = 97.1 bits (231), Expect = 6e-19
Identities = 69/254 (27%), Positives = 117/254 (46%), Gaps = 2/254 (0%)
Query: 15 ESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDIS 74
E N+ L L N + EI+++A L +DLS+N + + F L+ +++S
Sbjct: 117 EPTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQ-LKYLNLS 175
Query: 75 NNRVVYVPSDSFLGLYS-LQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAF 133
NNR+ + + F L S L ++ L++N++ I F L +LQ L+L N+I + F
Sbjct: 176 NNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTF 235
Query: 134 ENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLK 193
+ RN + + F L + L+L +NNL + L++L+ L +
Sbjct: 236 QGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVS 295
Query: 194 ENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAF 253
+NA+ +I + + C L +LDLS N+L ++ +AF G + F
Sbjct: 296 QNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVF 355
Query: 254 SMLKNLTTLYLDGN 267
L NL TL L N
Sbjct: 356 RFLSNLQTLDLRNN 369
Score = 76.6 bits (180), Expect = 9e-13
Identities = 58/198 (29%), Positives = 97/198 (48%), Gaps = 5/198 (2%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L G F L N++ L L+ N L ++ + L + +S N + + +
Sbjct: 249 NGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWE 308
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L +D+S N++ + +F+GL L+ L+L N++ +I +G F L NLQ L L +
Sbjct: 309 FCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRN 368
Query: 123 NKIN-NISD--NAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
N+I+ I D AF N++K+I + F L+ L LDL+NN +MS+
Sbjct: 369 NEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQEN 428
Query: 180 EFESLKLLRNLDLKENAL 197
F S L+ L L ++L
Sbjct: 429 AF-SQTHLKELILNTSSL 445
Score = 51.6 bits (118), Expect = 3e-05
Identities = 28/87 (32%), Positives = 47/87 (54%), Gaps = 3/87 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLE---EIDSEAFTSTKKLFHVDLSNNYLYTLPE 59
DN V ++ G+F L NL+TL L+ N + E SEAF L + L N + ++ +
Sbjct: 344 DNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITK 403
Query: 60 KLFANNTFLETIDISNNRVVYVPSDSF 86
K F LE +D++NN ++ + ++F
Sbjct: 404 KAFIGLESLEHLDLNNNAIMSIQENAF 430
>BC045113-1|AAH45113.1| 522|Homo sapiens LRRTM1 protein protein.
Length = 522
Score = 105 bits (252), Expect = 2e-21
Identities = 82/303 (27%), Positives = 135/303 (44%), Gaps = 6/303 (1%)
Query: 29 YLEEID-SEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFL 87
Y E ++ +EA + L + L N L L F L + + +N + V D+F
Sbjct: 51 YCEALNLTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQ 110
Query: 88 GLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDR 146
L ++ L LS N+I + N TF + NL+ + LS NK+ ++ + F
Sbjct: 111 KLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRA 170
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N ++ +P ++F + + L FLD+ N L SLA F L L L L+ N L ++ F
Sbjct: 171 NAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFP 230
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXY-EVHFKAFSMLKNLTTLYLD 265
+L L L +NK+ + + + Y E H F + +L +L LD
Sbjct: 231 RLISLHSLCLRRNKVAIVVSSLDWVWNLEKMDLSGNEIEYMEPH--VFETVPHLQSLQLD 288
Query: 266 GNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWY 325
N + R L+ LT + L+GN W C + +++W+ N +D + C SP Y
Sbjct: 289 SNRLTYIEPRILNSWKSLTSITLAGNLWDCGRNVCALASWLS-NFQGRYDGNLQCASPEY 347
Query: 326 LEG 328
+G
Sbjct: 348 AQG 350
Score = 79.0 bits (186), Expect = 2e-13
Identities = 55/222 (24%), Positives = 100/222 (45%), Gaps = 2/222 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L G F L+ L L L N++ + +AF +++ + LS+N + LP F
Sbjct: 75 NSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFR 134
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L ++D+S N++ + D F GL L L + N IQ + F ++L+ L +
Sbjct: 135 PMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGY 194
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N++ +++ N+F + N L + F L L L L N +++ +
Sbjct: 195 NQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNK-VAIVVSSLD 253
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ L +DL N + + + F +L+ L L N+L +I
Sbjct: 254 WVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLTYI 295
Score = 75.4 bits (177), Expect = 2e-12
Identities = 58/217 (26%), Positives = 99/217 (45%), Gaps = 2/217 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ + G F+ L +K L L N + ++ + F L VDLS N L L LF
Sbjct: 99 NHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFH 158
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L T+ + N + +VP F SL+ LD+ N+++++ +F+ L L L L
Sbjct: 159 GLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEH 218
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + ++ F RNK+ + + L + + L +DLS N + + FE
Sbjct: 219 NDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSL-DWVWNLEKMDLSGNEIEYMEPHVFE 277
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
++ L++L L N L+ I + +L + L+ N
Sbjct: 278 TVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
>AY358310-1|AAQ88677.1| 522|Homo sapiens DFLL675 protein.
Length = 522
Score = 105 bits (252), Expect = 2e-21
Identities = 82/303 (27%), Positives = 135/303 (44%), Gaps = 6/303 (1%)
Query: 29 YLEEID-SEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFL 87
Y E ++ +EA + L + L N L L F L + + +N + V D+F
Sbjct: 51 YCEALNLTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQ 110
Query: 88 GLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDR 146
L ++ L LS N+I + N TF + NL+ + LS NK+ ++ + F
Sbjct: 111 KLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRA 170
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N ++ +P ++F + + L FLD+ N L SLA F L L L L+ N L ++ F
Sbjct: 171 NAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFP 230
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXY-EVHFKAFSMLKNLTTLYLD 265
+L L L +NK+ + + + Y E H F + +L +L LD
Sbjct: 231 RLISLHSLCLRRNKVAIVVSSLDWVWNLEKMDLSGNEIEYMEPH--VFETVPHLQSLQLD 288
Query: 266 GNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWY 325
N + R L+ LT + L+GN W C + +++W+ N +D + C SP Y
Sbjct: 289 SNRLTYIEPRILNSWKSLTSITLAGNLWDCGRNVCALASWLS-NFQGRYDGNLQCASPEY 347
Query: 326 LEG 328
+G
Sbjct: 348 AQG 350
Score = 79.0 bits (186), Expect = 2e-13
Identities = 55/222 (24%), Positives = 100/222 (45%), Gaps = 2/222 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L G F L+ L L L N++ + +AF +++ + LS+N + LP F
Sbjct: 75 NSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFR 134
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L ++D+S N++ + D F GL L L + N IQ + F ++L+ L +
Sbjct: 135 PMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGY 194
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N++ +++ N+F + N L + F L L L L N +++ +
Sbjct: 195 NQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNK-VAIVVSSLD 253
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ L +DL N + + + F +L+ L L N+L +I
Sbjct: 254 WVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLTYI 295
Score = 75.4 bits (177), Expect = 2e-12
Identities = 58/217 (26%), Positives = 99/217 (45%), Gaps = 2/217 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ + G F+ L +K L L N + ++ + F L VDLS N L L LF
Sbjct: 99 NHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFH 158
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L T+ + N + +VP F SL+ LD+ N+++++ +F+ L L L L
Sbjct: 159 GLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEH 218
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + ++ F RNK+ + + L + + L +DLS N + + FE
Sbjct: 219 NDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSL-DWVWNLEKMDLSGNEIEYMEPHVFE 277
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
++ L++L L N L+ I + +L + L+ N
Sbjct: 278 TVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
>AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 105 bits (252), Expect = 2e-21
Identities = 82/316 (25%), Positives = 139/316 (43%), Gaps = 8/316 (2%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTS-TKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNN 76
+ LK L L N + +++ F + + L V L+ N + +P K+F L+ +++ N
Sbjct: 167 MQLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIF-KLPHLQFLELKRN 225
Query: 77 RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFEN 135
R+ V +F GL SL+ L + +N I +++G F L N++ L+L N + ++
Sbjct: 226 RIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYG 285
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
+N ++ I + + L LDLS N L L F L LL L+L +N
Sbjct: 286 LRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDN 345
Query: 196 ALSQIPDNTFSDCFNLEKLDLSKNKLRFI---NITAFYGXXXXXXXXXXXXXXYEVHFKA 252
++ I D F NL+ LDL N++ + AF G + KA
Sbjct: 346 RVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKA 405
Query: 253 FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMK 312
F L++L L L+ N S+ L + L+ + CDCH ++ W+ N +
Sbjct: 406 FIGLESLEHLDLNNNAIMSIQENAFS-QTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQ 464
Query: 313 IWDYSPTCVSPWYLEG 328
+ +C P +L G
Sbjct: 465 -HSVNVSCAHPEWLAG 479
Score = 97.1 bits (231), Expect = 6e-19
Identities = 69/254 (27%), Positives = 117/254 (46%), Gaps = 2/254 (0%)
Query: 15 ESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDIS 74
E N+ L L N + EI+++A L +DLS+N + + F L+ +++S
Sbjct: 117 EPTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQ-LKYLNLS 175
Query: 75 NNRVVYVPSDSFLGLYS-LQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAF 133
NNR+ + + F L S L ++ L++N++ I F L +LQ L+L N+I + F
Sbjct: 176 NNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTF 235
Query: 134 ENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLK 193
+ RN + + F L + L+L +NNL + L++L+ L +
Sbjct: 236 QGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVS 295
Query: 194 ENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAF 253
+NA+ +I + + C L +LDLS N+L ++ +AF G + F
Sbjct: 296 QNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVF 355
Query: 254 SMLKNLTTLYLDGN 267
L NL TL L N
Sbjct: 356 RFLSNLQTLDLRNN 369
Score = 76.6 bits (180), Expect = 9e-13
Identities = 58/198 (29%), Positives = 97/198 (48%), Gaps = 5/198 (2%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L G F L N++ L L+ N L ++ + L + +S N + + +
Sbjct: 249 NGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWE 308
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L +D+S N++ + +F+GL L+ L+L N++ +I +G F L NLQ L L +
Sbjct: 309 FCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRN 368
Query: 123 NKIN-NISD--NAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
N+I+ I D AF N++K+I + F L+ L LDL+NN +MS+
Sbjct: 369 NEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQEN 428
Query: 180 EFESLKLLRNLDLKENAL 197
F S L+ L L ++L
Sbjct: 429 AF-SQTHLKELILNTSSL 445
Score = 51.6 bits (118), Expect = 3e-05
Identities = 28/87 (32%), Positives = 47/87 (54%), Gaps = 3/87 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLE---EIDSEAFTSTKKLFHVDLSNNYLYTLPE 59
DN V ++ G+F L NL+TL L+ N + E SEAF L + L N + ++ +
Sbjct: 344 DNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITK 403
Query: 60 KLFANNTFLETIDISNNRVVYVPSDSF 86
K F LE +D++NN ++ + ++F
Sbjct: 404 KAFIGLESLEHLDLNNNAIMSIQENAF 430
>AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein.
Length = 1073
Score = 105 bits (252), Expect = 2e-21
Identities = 82/316 (25%), Positives = 139/316 (43%), Gaps = 8/316 (2%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTS-TKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNN 76
+ LK L L N + +++ F + + L V L+ N + +P K+F L+ +++ N
Sbjct: 175 MQLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIF-KLPHLQFLELKRN 233
Query: 77 RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFEN 135
R+ V +F GL SL+ L + +N I +++G F L N++ L+L N + ++
Sbjct: 234 RIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYG 293
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
+N ++ I + + L LDLS N L L F L LL L+L +N
Sbjct: 294 LRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDN 353
Query: 196 ALSQIPDNTFSDCFNLEKLDLSKNKLRFI---NITAFYGXXXXXXXXXXXXXXYEVHFKA 252
++ I D F NL+ LDL N++ + AF G + KA
Sbjct: 354 RVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKA 413
Query: 253 FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMK 312
F L++L L L+ N S+ L + L+ + CDCH ++ W+ N +
Sbjct: 414 FIGLESLEHLDLNNNAIMSIQENAFS-QTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQ 472
Query: 313 IWDYSPTCVSPWYLEG 328
+ +C P +L G
Sbjct: 473 -HSVNVSCAHPEWLAG 487
Score = 97.1 bits (231), Expect = 6e-19
Identities = 69/254 (27%), Positives = 117/254 (46%), Gaps = 2/254 (0%)
Query: 15 ESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDIS 74
E N+ L L N + EI+++A L +DLS+N + + F L+ +++S
Sbjct: 125 EPTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQ-LKYLNLS 183
Query: 75 NNRVVYVPSDSFLGLYS-LQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAF 133
NNR+ + + F L S L ++ L++N++ I F L +LQ L+L N+I + F
Sbjct: 184 NNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTF 243
Query: 134 ENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLK 193
+ RN + + F L + L+L +NNL + L++L+ L +
Sbjct: 244 QGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVS 303
Query: 194 ENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAF 253
+NA+ +I + + C L +LDLS N+L ++ +AF G + F
Sbjct: 304 QNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVF 363
Query: 254 SMLKNLTTLYLDGN 267
L NL TL L N
Sbjct: 364 RFLSNLQTLDLRNN 377
Score = 76.6 bits (180), Expect = 9e-13
Identities = 58/198 (29%), Positives = 97/198 (48%), Gaps = 5/198 (2%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L G F L N++ L L+ N L ++ + L + +S N + + +
Sbjct: 257 NGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWE 316
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L +D+S N++ + +F+GL L+ L+L N++ +I +G F L NLQ L L +
Sbjct: 317 FCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRN 376
Query: 123 NKIN-NISD--NAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
N+I+ I D AF N++K+I + F L+ L LDL+NN +MS+
Sbjct: 377 NEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQEN 436
Query: 180 EFESLKLLRNLDLKENAL 197
F S L+ L L ++L
Sbjct: 437 AF-SQTHLKELILNTSSL 453
Score = 51.6 bits (118), Expect = 3e-05
Identities = 28/87 (32%), Positives = 47/87 (54%), Gaps = 3/87 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLE---EIDSEAFTSTKKLFHVDLSNNYLYTLPE 59
DN V ++ G+F L NL+TL L+ N + E SEAF L + L N + ++ +
Sbjct: 352 DNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITK 411
Query: 60 KLFANNTFLETIDISNNRVVYVPSDSF 86
K F LE +D++NN ++ + ++F
Sbjct: 412 KAFIGLESLEHLDLNNNAIMSIQENAF 438
>DQ084202-1|AAY86709.1| 640|Homo sapiens netrin-G1 ligand splice
variant 4 protein.
Length = 640
Score = 104 bits (249), Expect = 4e-21
Identities = 77/272 (28%), Positives = 125/272 (45%), Gaps = 4/272 (1%)
Query: 65 NTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDN 123
+T +++ N++ + +SF L L+IL LS+N I+ I+ G F+ N L+L DN
Sbjct: 75 STNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGPANPNTLELFDN 134
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMS-LAGVEFE 182
++ I + AF N +++IP+ FN + L LDL +S ++ FE
Sbjct: 135 RLATIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFE 194
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L LR L+L L +IP+ T L++LDLS N L I +F G
Sbjct: 195 GLSNLRYLNLAMCNLREIPNLT--PLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQ 252
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYI 302
+ AF L++L + L N LP + L + L NPW+C+C L++
Sbjct: 253 SQIRVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWL 312
Query: 303 SAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKL 334
S W++ C +P L+G ++ +L
Sbjct: 313 SWWIKDMAPSNTACCARCNTPPNLKGRYIGEL 344
Score = 73.3 bits (172), Expect = 8e-12
Identities = 55/208 (26%), Positives = 103/208 (49%), Gaps = 4/208 (1%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L N ++ I +F + L + LS N++ T+ F T+++ +NR+
Sbjct: 77 NTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGPANPNTLELFDNRL 136
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD-NKINNISDNAFENX 136
+P+ +F+ L L+ L L N I++I + F+ + +L+ L L + +++ IS+ AFE
Sbjct: 137 ATIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGL 196
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
L+ IP L L LDLS N+L ++ F+ L L+ L + ++
Sbjct: 197 SNLRYLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQ 254
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ I N F + +L +++L+ N L +
Sbjct: 255 IRVIERNAFDNLQSLVEINLAHNNLTLL 282
Score = 71.3 bits (167), Expect = 3e-11
Identities = 56/221 (25%), Positives = 104/221 (47%), Gaps = 4/221 (1%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N ++ + F+ L +L+ L+L RN++ I+ AF ++L +N L T+P
Sbjct: 83 LHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGPANPNTLELFDNRLATIPNG 142
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSK-NKIQNIQNGTF-SLKNLQIL 118
F + L+ + + NN + +PS +F + SL+ LDL + ++ I G F L NL+ L
Sbjct: 143 AFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYL 202
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
L+ + I + N L I F L L L + + + +
Sbjct: 203 NLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIRVIER 260
Query: 179 VEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
F++L+ L ++L N L+ +P + F+ +LE++ L N
Sbjct: 261 NAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
>BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein.
Length = 1070
Score = 104 bits (249), Expect = 4e-21
Identities = 73/273 (26%), Positives = 122/273 (44%), Gaps = 4/273 (1%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
++L L N EID F L V L+NN L +P L A ++ + ++ + +N++
Sbjct: 71 RSLNLSYNKFSEIDPAGFEDLPNLQEVYLNNNELTAVPS-LGAASSHVVSLFLQHNKIRS 129
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTFSL-KNLQILKLSDNKINNISDNAFENXXXX 139
V SL++LDLS N I ++N F ++ L L+ N+I + AF+
Sbjct: 130 VEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRS 189
Query: 140 XXXXX-DRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALS 198
+N++ +P + F L L LDL+ N + + G+ F+ L L L L+ N +S
Sbjct: 190 LLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNIS 248
Query: 199 QIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKN 258
++ D F + L L N L +N + YG +H K +S +
Sbjct: 249 KLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQK 308
Query: 259 LTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L L L N L +L + L++++LS N
Sbjct: 309 LHELVLSFNNLTRLDEESLAELSSLSVLRLSHN 341
Score = 95.1 bits (226), Expect = 2e-18
Identities = 85/330 (25%), Positives = 138/330 (41%), Gaps = 7/330 (2%)
Query: 4 NHVEYLPGGIFESLV-NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
N + L G F+ L +L TLRL +N + ++ AF +L +DL+ N + + F
Sbjct: 173 NRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAF-KLPRLTQLDLNRNRIRLIEGLTF 231
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT-FSLKNLQILKLS 121
LE + + N + + +F GL + +L L N + + +G+ + L L L LS
Sbjct: 232 QGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLS 291
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
+N I I + N L + + L L L LS+N++ +A F
Sbjct: 292 NNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAF 351
Query: 182 ESLKLLRNLDLKENALSQIPDNT---FSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXX 238
+ L+ LR LDL N +S ++T FS +L KL L + +
Sbjct: 352 KGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLLLLEPSQSAGCSSPSQPHMSAGGR 411
Query: 239 XXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCH 298
V +AFS L+ L L L GN S+ M L + +S + + CDC
Sbjct: 412 TLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHISSDSFLCDCQ 471
Query: 299 ALYISAWVRLNEMKIWDYSPTCVSPWYLEG 328
++ W+ + M + TC P L+G
Sbjct: 472 LKWLPPWL-IGRMLQAFVTATCAHPESLKG 500
>CR456360-1|CAG30246.1| 473|Homo sapiens Em:AC007663.1 protein.
Length = 473
Score = 103 bits (246), Expect = 9e-21
Identities = 78/249 (31%), Positives = 110/249 (44%), Gaps = 4/249 (1%)
Query: 93 QILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXX-XDRNKLK 150
Q + L N+I ++ +F + +NL IL L N + I AF D +L+
Sbjct: 60 QRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLR 119
Query: 151 NIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFN 210
++ F+ L L L L L L F L L+ L L++NAL +PD+TF D N
Sbjct: 120 SVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGN 179
Query: 211 LEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFP 270
L L L N++ + AF G VH AF L L TLYL N
Sbjct: 180 LTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLS 239
Query: 271 SLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHF 330
+LP+ L + L ++L+ NPW CDC A + AW L + + C P L G
Sbjct: 240 ALPTEALAPLRALQYLRLNDNPWVCDCRARPLWAW--LQKFRGSSSEVPCSLPQRLAGRD 297
Query: 331 LKKLKFPEL 339
LK+L +L
Sbjct: 298 LKRLAANDL 306
Score = 79.0 bits (186), Expect = 2e-13
Identities = 58/194 (29%), Positives = 91/194 (46%), Gaps = 2/194 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNN-YLYTLPEKLF 62
N + ++P F + NL L L N L ID+ AFT L +DLS+N L ++ F
Sbjct: 67 NRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATF 126
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
L T+ + + + F GL +LQ L L N +Q + + TF L NL L L
Sbjct: 127 HGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLH 186
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N+I+++ + AF +N++ ++ F +L L+ L L NNL +L
Sbjct: 187 GNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEAL 246
Query: 182 ESLKLLRNLDLKEN 195
L+ L+ L L +N
Sbjct: 247 APLRALQYLRLNDN 260
Score = 52.8 bits (121), Expect = 1e-05
Identities = 45/175 (25%), Positives = 72/175 (41%), Gaps = 2/175 (1%)
Query: 49 LSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKN-KIQNIQN 107
L N + +P F L + + +N + + + +F GL L+ LDLS N +++++
Sbjct: 64 LHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDP 123
Query: 108 GTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFL 166
TF L L L L + + F N L+ +P F +L L L
Sbjct: 124 ATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHL 183
Query: 167 DLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
L N + S+ F L L L L +N ++ + + F D L L L N L
Sbjct: 184 FLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNL 238
>BC011787-1|AAH11787.1| 473|Homo sapiens reticulon 4 receptor
protein.
Length = 473
Score = 103 bits (246), Expect = 9e-21
Identities = 78/249 (31%), Positives = 110/249 (44%), Gaps = 4/249 (1%)
Query: 93 QILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXX-XDRNKLK 150
Q + L N+I ++ +F + +NL IL L N + I AF D +L+
Sbjct: 60 QRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLR 119
Query: 151 NIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFN 210
++ F+ L L L L L L F L L+ L L++NAL +PD+TF D N
Sbjct: 120 SVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGN 179
Query: 211 LEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFP 270
L L L N++ + AF G VH AF L L TLYL N
Sbjct: 180 LTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLS 239
Query: 271 SLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHF 330
+LP+ L + L ++L+ NPW CDC A + AW L + + C P L G
Sbjct: 240 ALPTEALAPLRALQYLRLNDNPWVCDCRARPLWAW--LQKFRGSSSEVPCSLPQRLAGRD 297
Query: 331 LKKLKFPEL 339
LK+L +L
Sbjct: 298 LKRLAANDL 306
Score = 79.0 bits (186), Expect = 2e-13
Identities = 58/194 (29%), Positives = 91/194 (46%), Gaps = 2/194 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNN-YLYTLPEKLF 62
N + ++P F + NL L L N L ID+ AFT L +DLS+N L ++ F
Sbjct: 67 NRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATF 126
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
L T+ + + + F GL +LQ L L N +Q + + TF L NL L L
Sbjct: 127 HGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLH 186
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N+I+++ + AF +N++ ++ F +L L+ L L NNL +L
Sbjct: 187 GNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEAL 246
Query: 182 ESLKLLRNLDLKEN 195
L+ L+ L L +N
Sbjct: 247 APLRALQYLRLNDN 260
Score = 52.8 bits (121), Expect = 1e-05
Identities = 45/175 (25%), Positives = 72/175 (41%), Gaps = 2/175 (1%)
Query: 49 LSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKN-KIQNIQN 107
L N + +P F L + + +N + + + +F GL L+ LDLS N +++++
Sbjct: 64 LHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDP 123
Query: 108 GTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFL 166
TF L L L L + + F N L+ +P F +L L L
Sbjct: 124 ATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHL 183
Query: 167 DLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
L N + S+ F L L L L +N ++ + + F D L L L N L
Sbjct: 184 FLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNL 238
>AY358297-1|AAQ88664.1| 473|Homo sapiens NOGOR protein.
Length = 473
Score = 103 bits (246), Expect = 9e-21
Identities = 78/249 (31%), Positives = 110/249 (44%), Gaps = 4/249 (1%)
Query: 93 QILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXX-XDRNKLK 150
Q + L N+I ++ +F + +NL IL L N + I AF D +L+
Sbjct: 60 QRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLR 119
Query: 151 NIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFN 210
++ F+ L L L L L L F L L+ L L++NAL +PD+TF D N
Sbjct: 120 SVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGN 179
Query: 211 LEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFP 270
L L L N++ + AF G VH AF L L TLYL N
Sbjct: 180 LTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLS 239
Query: 271 SLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHF 330
+LP+ L + L ++L+ NPW CDC A + AW L + + C P L G
Sbjct: 240 ALPTEALAPLRALQYLRLNDNPWVCDCRARPLWAW--LQKFRGSSSEVPCSLPQRLAGRD 297
Query: 331 LKKLKFPEL 339
LK+L +L
Sbjct: 298 LKRLAANDL 306
Score = 79.0 bits (186), Expect = 2e-13
Identities = 58/194 (29%), Positives = 91/194 (46%), Gaps = 2/194 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNN-YLYTLPEKLF 62
N + ++P F + NL L L N L ID+ AFT L +DLS+N L ++ F
Sbjct: 67 NRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATF 126
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
L T+ + + + F GL +LQ L L N +Q + + TF L NL L L
Sbjct: 127 HGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLH 186
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N+I+++ + AF +N++ ++ F +L L+ L L NNL +L
Sbjct: 187 GNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEAL 246
Query: 182 ESLKLLRNLDLKEN 195
L+ L+ L L +N
Sbjct: 247 APLRALQYLRLNDN 260
Score = 52.8 bits (121), Expect = 1e-05
Identities = 45/175 (25%), Positives = 72/175 (41%), Gaps = 2/175 (1%)
Query: 49 LSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKN-KIQNIQN 107
L N + +P F L + + +N + + + +F GL L+ LDLS N +++++
Sbjct: 64 LHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDP 123
Query: 108 GTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFL 166
TF L L L L + + F N L+ +P F +L L L
Sbjct: 124 ATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHL 183
Query: 167 DLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
L N + S+ F L L L L +N ++ + + F D L L L N L
Sbjct: 184 FLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNL 238
>AK172751-1|BAD18737.1| 653|Homo sapiens protein ( Homo sapiens
cDNA FLJ23912 fis, clone CAE04210, highly similar to
Homo sapiens leucine rich repeat containing 4 (LRRC4).
).
Length = 653
Score = 103 bits (246), Expect = 9e-21
Identities = 76/280 (27%), Positives = 128/280 (45%), Gaps = 7/280 (2%)
Query: 54 LYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-L 112
L +P+ + +N +L ++ N + + +D+F L+ L++L L +N I+ I+ G F+ L
Sbjct: 66 LSEVPQGIPSNTRYLNLME---NNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGL 122
Query: 113 KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSN-N 171
+L L+L DN + I AFE N +++IP+ FN + L+ LDL
Sbjct: 123 ASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELK 182
Query: 172 NLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
L ++ FE L L+ L+L + +P+ T LE+L++S N I +F+G
Sbjct: 183 KLEYISEGAFEGLFNLKYLNLGMCNIKDMPNLT--PLVGLEELEMSGNHFPEIRPGSFHG 240
Query: 232 XXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ AF L +L L L N SLP + L + L +
Sbjct: 241 LSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHD 300
Query: 292 PWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFL 331
PW+CDC L+++ W R C +P ++ G +L
Sbjct: 301 PWNCDCDILWLAWWFREYIPTNSTCCGRCHAPMHMRGRYL 340
Score = 71.3 bits (167), Expect = 3e-11
Identities = 58/218 (26%), Positives = 100/218 (45%), Gaps = 4/218 (1%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N+++ + F L +L+ L+L RN + +I+ AF L ++L +N+L +P
Sbjct: 82 LMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSG 141
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSK-NKIQNIQNGTF-SLKNLQIL 118
F + L + + NN + +PS +F + SL LDL + K++ I G F L NL+ L
Sbjct: 142 AFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYL 201
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
L I ++ + N I F+ L L L + N+ + +
Sbjct: 202 NLGMCNIKDMPN--LTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIER 259
Query: 179 VEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDL 216
F+ L L L+L N LS +P + F+ L +L L
Sbjct: 260 NAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHL 297
>AF283463-1|AAG53612.1| 473|Homo sapiens Nogo receptor protein.
Length = 473
Score = 103 bits (246), Expect = 9e-21
Identities = 78/249 (31%), Positives = 110/249 (44%), Gaps = 4/249 (1%)
Query: 93 QILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXX-XDRNKLK 150
Q + L N+I ++ +F + +NL IL L N + I AF D +L+
Sbjct: 60 QRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLR 119
Query: 151 NIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFN 210
++ F+ L L L L L L F L L+ L L++NAL +PD+TF D N
Sbjct: 120 SVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGN 179
Query: 211 LEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFP 270
L L L N++ + AF G VH AF L L TLYL N
Sbjct: 180 LTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLS 239
Query: 271 SLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHF 330
+LP+ L + L ++L+ NPW CDC A + AW L + + C P L G
Sbjct: 240 ALPTEALAPLRALQYLRLNDNPWVCDCRARPLWAW--LQKFRGSSSEVPCSLPQRLAGRD 297
Query: 331 LKKLKFPEL 339
LK+L +L
Sbjct: 298 LKRLAANDL 306
Score = 79.0 bits (186), Expect = 2e-13
Identities = 58/194 (29%), Positives = 91/194 (46%), Gaps = 2/194 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNN-YLYTLPEKLF 62
N + ++P F + NL L L N L ID+ AFT L +DLS+N L ++ F
Sbjct: 67 NRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATF 126
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
L T+ + + + F GL +LQ L L N +Q + + TF L NL L L
Sbjct: 127 HGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLH 186
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N+I+++ + AF +N++ ++ F +L L+ L L NNL +L
Sbjct: 187 GNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEAL 246
Query: 182 ESLKLLRNLDLKEN 195
L+ L+ L L +N
Sbjct: 247 APLRALQYLRLNDN 260
Score = 52.8 bits (121), Expect = 1e-05
Identities = 45/175 (25%), Positives = 72/175 (41%), Gaps = 2/175 (1%)
Query: 49 LSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKN-KIQNIQN 107
L N + +P F L + + +N + + + +F GL L+ LDLS N +++++
Sbjct: 64 LHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDP 123
Query: 108 GTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFL 166
TF L L L L + + F N L+ +P F +L L L
Sbjct: 124 ATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHL 183
Query: 167 DLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
L N + S+ F L L L L +N ++ + + F D L L L N L
Sbjct: 184 FLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNL 238
>AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein.
Length = 713
Score = 102 bits (244), Expect = 2e-20
Identities = 98/404 (24%), Positives = 167/404 (41%), Gaps = 12/404 (2%)
Query: 17 LVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNN 76
L NL L L +N + F + +L + L N L L + FA L+ + +++N
Sbjct: 92 LANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHN 151
Query: 77 RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFEN 135
++ + +F GL +L L L+ N ++ I + F L NL+IL + NK++ I D F
Sbjct: 152 QLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRP 211
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
L+ I L+ L L +N L + E + L+ LDL +N
Sbjct: 212 LANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKN 271
Query: 196 ALSQIPDNTFSDCFNLEKLDLSK-NKLRFINITAFYGXXXXXXXXXXXXXXYE-VHFKAF 253
L ++ F++ +L++L L+ +L I+ A +H +AF
Sbjct: 272 PLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAF 331
Query: 254 SMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKI 313
L + TL L+ N +L +T++ +P L V L GNP CDC + +A I
Sbjct: 332 HHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANA-TGTRVRFI 390
Query: 314 WDYSPTCVSPWYLEGHFLKKLKFPELCAGQWASMVNLSPRLPIQQLLALNVSVNRC---- 369
S C P L+ ++++ F E+ +++ P Q+ + V C
Sbjct: 391 EPQSTLCAEPPDLQRLPVREVPFREM-TDHCLPLISPRSFPPSLQVASGESMVLHCRALA 449
Query: 370 QMDGVIMWPIPVSESILDTHTG---YVLDRGTTDIEDITTIRYG 410
+ + I W P + H G V GT ++ +T G
Sbjct: 450 EPEPEIYWVTPAGLRLTPAHAGRRYRVYPEGTLELRRVTAEEAG 493
Score = 75.8 bits (178), Expect = 2e-12
Identities = 60/203 (29%), Positives = 89/203 (43%), Gaps = 1/203 (0%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
+TL LQ N + +D L +DLS N + F L ++ + N++
Sbjct: 72 QTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTR 131
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXX 139
+ SF GL SLQ L L+ N++ I FS L NL L L+ N + I FE
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNL 191
Query: 140 XXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ 199
NK+ I F L L L L+ NL ++ E L+ L +L +N L++
Sbjct: 192 EILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLAR 251
Query: 200 IPDNTFSDCFNLEKLDLSKNKLR 222
+P L+ LDL+KN L+
Sbjct: 252 VPRRALEQVPGLKFLDLNKNPLQ 274
Score = 65.7 bits (153), Expect = 2e-09
Identities = 59/222 (26%), Positives = 97/222 (43%), Gaps = 3/222 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + L F L +L+ L L N L I AF+ L + L++N L + + F
Sbjct: 126 ENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWF 185
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
LE + I N+V + +F L +L+ L L+ ++ I + L++L+ L
Sbjct: 186 EMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFY 245
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSN-NNLMSLAGVE 180
DN++ + A E ++N L+ + F N+ L L L+N L+S+
Sbjct: 246 DNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFA 305
Query: 181 FESLKLLRNLDLKEN-ALSQIPDNTFSDCFNLEKLDLSKNKL 221
+L L LD+ N LS I F +E L L+ N L
Sbjct: 306 LVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNAL 347
Score = 58.4 bits (135), Expect = 3e-07
Identities = 36/124 (29%), Positives = 58/124 (46%)
Query: 168 LSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINIT 227
L +N+++ + E L L LDL +N+ S D F L L L +N+L +
Sbjct: 76 LQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDH 135
Query: 228 AFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVK 287
+F G Y + +AFS L NL L+L+ N+ ++ SR + +P L I+
Sbjct: 136 SFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILM 195
Query: 288 LSGN 291
+ GN
Sbjct: 196 IGGN 199
Score = 55.2 bits (127), Expect = 2e-06
Identities = 38/144 (26%), Positives = 64/144 (44%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N + + L L LDLS N+ +F +L L +L L+EN L+++ D++F+
Sbjct: 79 NSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFA 138
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
+L++L L+ N+L I AF G + + F ML NL L + G
Sbjct: 139 GLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGG 198
Query: 267 NMFPSLPSRTLDYMPKLTIVKLSG 290
N ++ + L + L+G
Sbjct: 199 NKVDAILDMNFRPLANLRSLVLAG 222
>AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat
neuronal 5 protein.
Length = 713
Score = 102 bits (244), Expect = 2e-20
Identities = 98/404 (24%), Positives = 167/404 (41%), Gaps = 12/404 (2%)
Query: 17 LVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNN 76
L NL L L +N + F + +L + L N L L + FA L+ + +++N
Sbjct: 92 LANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHN 151
Query: 77 RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFEN 135
++ + +F GL +L L L+ N ++ I + F L NL+IL + NK++ I D F
Sbjct: 152 QLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRP 211
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
L+ I L+ L L +N L + E + L+ LDL +N
Sbjct: 212 LANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKN 271
Query: 196 ALSQIPDNTFSDCFNLEKLDLSK-NKLRFINITAFYGXXXXXXXXXXXXXXYE-VHFKAF 253
L ++ F++ +L++L L+ +L I+ A +H +AF
Sbjct: 272 PLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAF 331
Query: 254 SMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKI 313
L + TL L+ N +L +T++ +P L V L GNP CDC + +A I
Sbjct: 332 HHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANA-TGTRVRFI 390
Query: 314 WDYSPTCVSPWYLEGHFLKKLKFPELCAGQWASMVNLSPRLPIQQLLALNVSVNRC---- 369
S C P L+ ++++ F E+ +++ P Q+ + V C
Sbjct: 391 EPQSTLCAEPPDLQRLPVREVPFREM-TDHCLPLISPRSFPPSLQVASGESMVLHCRALA 449
Query: 370 QMDGVIMWPIPVSESILDTHTG---YVLDRGTTDIEDITTIRYG 410
+ + I W P + H G V GT ++ +T G
Sbjct: 450 EPEPEIYWVTPAGLRLTPAHAGRRYRVYPEGTLELRRVTAEEAG 493
Score = 75.8 bits (178), Expect = 2e-12
Identities = 60/203 (29%), Positives = 89/203 (43%), Gaps = 1/203 (0%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
+TL LQ N + +D L +DLS N + F L ++ + N++
Sbjct: 72 QTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTR 131
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXX 139
+ SF GL SLQ L L+ N++ I FS L NL L L+ N + I FE
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNL 191
Query: 140 XXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ 199
NK+ I F L L L L+ NL ++ E L+ L +L +N L++
Sbjct: 192 EILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLAR 251
Query: 200 IPDNTFSDCFNLEKLDLSKNKLR 222
+P L+ LDL+KN L+
Sbjct: 252 VPRRALEQVPGLKFLDLNKNPLQ 274
Score = 65.7 bits (153), Expect = 2e-09
Identities = 59/222 (26%), Positives = 97/222 (43%), Gaps = 3/222 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + L F L +L+ L L N L I AF+ L + L++N L + + F
Sbjct: 126 ENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWF 185
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
LE + I N+V + +F L +L+ L L+ ++ I + L++L+ L
Sbjct: 186 EMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFY 245
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSN-NNLMSLAGVE 180
DN++ + A E ++N L+ + F N+ L L L+N L+S+
Sbjct: 246 DNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFA 305
Query: 181 FESLKLLRNLDLKEN-ALSQIPDNTFSDCFNLEKLDLSKNKL 221
+L L LD+ N LS I F +E L L+ N L
Sbjct: 306 LVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNAL 347
Score = 58.4 bits (135), Expect = 3e-07
Identities = 36/124 (29%), Positives = 58/124 (46%)
Query: 168 LSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINIT 227
L +N+++ + E L L LDL +N+ S D F L L L +N+L +
Sbjct: 76 LQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDH 135
Query: 228 AFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVK 287
+F G Y + +AFS L NL L+L+ N+ ++ SR + +P L I+
Sbjct: 136 SFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILM 195
Query: 288 LSGN 291
+ GN
Sbjct: 196 IGGN 199
Score = 55.2 bits (127), Expect = 2e-06
Identities = 38/144 (26%), Positives = 64/144 (44%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N + + L L LDLS N+ +F +L L +L L+EN L+++ D++F+
Sbjct: 79 NSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFA 138
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
+L++L L+ N+L I AF G + + F ML NL L + G
Sbjct: 139 GLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGG 198
Query: 267 NMFPSLPSRTLDYMPKLTIVKLSG 290
N ++ + L + L+G
Sbjct: 199 NKVDAILDMNFRPLANLRSLVLAG 222
>AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on
chromosome 1 protein protein.
Length = 713
Score = 102 bits (244), Expect = 2e-20
Identities = 98/404 (24%), Positives = 167/404 (41%), Gaps = 12/404 (2%)
Query: 17 LVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNN 76
L NL L L +N + F + +L + L N L L + FA L+ + +++N
Sbjct: 92 LANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHN 151
Query: 77 RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFEN 135
++ + +F GL +L L L+ N ++ I + F L NL+IL + NK++ I D F
Sbjct: 152 QLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRP 211
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
L+ I L+ L L +N L + E + L+ LDL +N
Sbjct: 212 LANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKN 271
Query: 196 ALSQIPDNTFSDCFNLEKLDLSK-NKLRFINITAFYGXXXXXXXXXXXXXXYE-VHFKAF 253
L ++ F++ +L++L L+ +L I+ A +H +AF
Sbjct: 272 PLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAF 331
Query: 254 SMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKI 313
L + TL L+ N +L +T++ +P L V L GNP CDC + +A I
Sbjct: 332 HHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANA-TGTRVRFI 390
Query: 314 WDYSPTCVSPWYLEGHFLKKLKFPELCAGQWASMVNLSPRLPIQQLLALNVSVNRC---- 369
S C P L+ ++++ F E+ +++ P Q+ + V C
Sbjct: 391 EPQSTLCAEPPDLQRLPVREVPFREM-TDHCLPLISPRSFPPSLQVASGESMVLHCRALA 449
Query: 370 QMDGVIMWPIPVSESILDTHTG---YVLDRGTTDIEDITTIRYG 410
+ + I W P + H G V GT ++ +T G
Sbjct: 450 EPEPEIYWVTPAGLRLTPAHAGRRCRVYPEGTLELRRVTAEEAG 493
Score = 75.8 bits (178), Expect = 2e-12
Identities = 60/203 (29%), Positives = 89/203 (43%), Gaps = 1/203 (0%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
+TL LQ N + +D L +DLS N + F L ++ + N++
Sbjct: 72 QTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTR 131
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXX 139
+ SF GL SLQ L L+ N++ I FS L NL L L+ N + I FE
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNL 191
Query: 140 XXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ 199
NK+ I F L L L L+ NL ++ E L+ L +L +N L++
Sbjct: 192 EILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLAR 251
Query: 200 IPDNTFSDCFNLEKLDLSKNKLR 222
+P L+ LDL+KN L+
Sbjct: 252 VPRRALEQVPGLKFLDLNKNPLQ 274
Score = 65.7 bits (153), Expect = 2e-09
Identities = 59/222 (26%), Positives = 97/222 (43%), Gaps = 3/222 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + L F L +L+ L L N L I AF+ L + L++N L + + F
Sbjct: 126 ENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWF 185
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
LE + I N+V + +F L +L+ L L+ ++ I + L++L+ L
Sbjct: 186 EMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFY 245
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSN-NNLMSLAGVE 180
DN++ + A E ++N L+ + F N+ L L L+N L+S+
Sbjct: 246 DNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFA 305
Query: 181 FESLKLLRNLDLKEN-ALSQIPDNTFSDCFNLEKLDLSKNKL 221
+L L LD+ N LS I F +E L L+ N L
Sbjct: 306 LVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNAL 347
Score = 58.4 bits (135), Expect = 3e-07
Identities = 36/124 (29%), Positives = 58/124 (46%)
Query: 168 LSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINIT 227
L +N+++ + E L L LDL +N+ S D F L L L +N+L +
Sbjct: 76 LQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDH 135
Query: 228 AFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVK 287
+F G Y + +AFS L NL L+L+ N+ ++ SR + +P L I+
Sbjct: 136 SFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILM 195
Query: 288 LSGN 291
+ GN
Sbjct: 196 IGGN 199
Score = 55.2 bits (127), Expect = 2e-06
Identities = 38/144 (26%), Positives = 64/144 (44%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N + + L L LDLS N+ +F +L L +L L+EN L+++ D++F+
Sbjct: 79 NSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFA 138
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
+L++L L+ N+L I AF G + + F ML NL L + G
Sbjct: 139 GLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGG 198
Query: 267 NMFPSLPSRTLDYMPKLTIVKLSG 290
N ++ + L + L+G
Sbjct: 199 NKVDAILDMNFRPLANLRSLVLAG 222
>BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat
neuronal 2 protein.
Length = 713
Score = 101 bits (242), Expect = 3e-20
Identities = 98/404 (24%), Positives = 166/404 (41%), Gaps = 12/404 (2%)
Query: 17 LVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNN 76
L NL L L +N + F + +L + L N L L + FA L+ + +++N
Sbjct: 92 LANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHN 151
Query: 77 RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFEN 135
++ + +F GL +L L L+ N ++ I + F L NL+IL + NK++ I D F
Sbjct: 152 QLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRP 211
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
L+ I L+ L L +N L + E + L+ LDL +N
Sbjct: 212 LANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKN 271
Query: 196 ALSQIPDNTFSDCFNLEKLDLSK-NKLRFINITAFYGXXXXXXXXXXXXXXYE-VHFKAF 253
L ++ F++ +L++L L+ +L I+ A +H +AF
Sbjct: 272 PLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAF 331
Query: 254 SMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKI 313
L + TL L+ N +L +T + +P L V L GNP CDC + +A I
Sbjct: 332 HHLPQMETLMLNNNALSALHQQTAESLPNLQEVGLHGNPIRCDCVIRWANA-TGTRVRFI 390
Query: 314 WDYSPTCVSPWYLEGHFLKKLKFPELCAGQWASMVNLSPRLPIQQLLALNVSVNRC---- 369
S C P L+ ++++ F E+ +++ P Q+ + V C
Sbjct: 391 EPQSTLCAEPPDLQRLPVREVPFREM-TDHCLPLISPRSFPPSLQVASGESMVLHCRALA 449
Query: 370 QMDGVIMWPIPVSESILDTHTG---YVLDRGTTDIEDITTIRYG 410
+ + I W P + H G V GT ++ +T G
Sbjct: 450 EPEPEIYWVTPAGLRLTPAHAGRRYRVYPEGTLELRRVTAEEAG 493
Score = 75.8 bits (178), Expect = 2e-12
Identities = 60/203 (29%), Positives = 89/203 (43%), Gaps = 1/203 (0%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
+TL LQ N + +D L +DLS N + F L ++ + N++
Sbjct: 72 QTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTR 131
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXX 139
+ SF GL SLQ L L+ N++ I FS L NL L L+ N + I FE
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNL 191
Query: 140 XXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ 199
NK+ I F L L L L+ NL ++ E L+ L +L +N L++
Sbjct: 192 EILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLAR 251
Query: 200 IPDNTFSDCFNLEKLDLSKNKLR 222
+P L+ LDL+KN L+
Sbjct: 252 VPRRALEQVPGLKFLDLNKNPLQ 274
Score = 65.7 bits (153), Expect = 2e-09
Identities = 59/222 (26%), Positives = 97/222 (43%), Gaps = 3/222 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + L F L +L+ L L N L I AF+ L + L++N L + + F
Sbjct: 126 ENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWF 185
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
LE + I N+V + +F L +L+ L L+ ++ I + L++L+ L
Sbjct: 186 EMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFY 245
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSN-NNLMSLAGVE 180
DN++ + A E ++N L+ + F N+ L L L+N L+S+
Sbjct: 246 DNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFA 305
Query: 181 FESLKLLRNLDLKEN-ALSQIPDNTFSDCFNLEKLDLSKNKL 221
+L L LD+ N LS I F +E L L+ N L
Sbjct: 306 LVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNAL 347
Score = 58.4 bits (135), Expect = 3e-07
Identities = 36/124 (29%), Positives = 58/124 (46%)
Query: 168 LSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINIT 227
L +N+++ + E L L LDL +N+ S D F L L L +N+L +
Sbjct: 76 LQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDH 135
Query: 228 AFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVK 287
+F G Y + +AFS L NL L+L+ N+ ++ SR + +P L I+
Sbjct: 136 SFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILM 195
Query: 288 LSGN 291
+ GN
Sbjct: 196 IGGN 199
Score = 55.2 bits (127), Expect = 2e-06
Identities = 38/144 (26%), Positives = 64/144 (44%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N + + L L LDLS N+ +F +L L +L L+EN L+++ D++F+
Sbjct: 79 NSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFA 138
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
+L++L L+ N+L I AF G + + F ML NL L + G
Sbjct: 139 GLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGG 198
Query: 267 NMFPSLPSRTLDYMPKLTIVKLSG 290
N ++ + L + L+G
Sbjct: 199 NKVDAILDMNFRPLANLRSLVLAG 222
>BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat
neuronal 2 protein.
Length = 713
Score = 101 bits (242), Expect = 3e-20
Identities = 98/404 (24%), Positives = 166/404 (41%), Gaps = 12/404 (2%)
Query: 17 LVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNN 76
L NL L L +N + F + +L + L N L L + FA L+ + +++N
Sbjct: 92 LANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHN 151
Query: 77 RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFEN 135
++ + +F GL +L L L+ N ++ I + F L NL+IL + NK++ I D F
Sbjct: 152 QLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRP 211
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
L+ I L+ L L +N L + E + L+ LDL +N
Sbjct: 212 LANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKN 271
Query: 196 ALSQIPDNTFSDCFNLEKLDLSK-NKLRFINITAFYGXXXXXXXXXXXXXXYE-VHFKAF 253
L ++ F++ +L++L L+ +L I+ A +H +AF
Sbjct: 272 PLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAF 331
Query: 254 SMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKI 313
L + TL L+ N +L +T + +P L V L GNP CDC + +A I
Sbjct: 332 HHLPQMETLMLNNNALSALHQQTAESLPNLQEVGLHGNPIRCDCVIRWANA-TGTRVRFI 390
Query: 314 WDYSPTCVSPWYLEGHFLKKLKFPELCAGQWASMVNLSPRLPIQQLLALNVSVNRC---- 369
S C P L+ ++++ F E+ +++ P Q+ + V C
Sbjct: 391 EPQSTLCAEPPDLQRLPVREVPFREM-TDHCLPLISPRSFPPSLQVASGESMVLHCRALA 449
Query: 370 QMDGVIMWPIPVSESILDTHTG---YVLDRGTTDIEDITTIRYG 410
+ + I W P + H G V GT ++ +T G
Sbjct: 450 EPEPEIYWVTPAGLRLTPAHAGRRYRVYPEGTLELRRVTAEEAG 493
Score = 75.8 bits (178), Expect = 2e-12
Identities = 60/203 (29%), Positives = 89/203 (43%), Gaps = 1/203 (0%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
+TL LQ N + +D L +DLS N + F L ++ + N++
Sbjct: 72 QTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTR 131
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXX 139
+ SF GL SLQ L L+ N++ I FS L NL L L+ N + I FE
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNL 191
Query: 140 XXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ 199
NK+ I F L L L L+ NL ++ E L+ L +L +N L++
Sbjct: 192 EILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLAR 251
Query: 200 IPDNTFSDCFNLEKLDLSKNKLR 222
+P L+ LDL+KN L+
Sbjct: 252 VPRRALEQVPGLKFLDLNKNPLQ 274
Score = 65.7 bits (153), Expect = 2e-09
Identities = 59/222 (26%), Positives = 97/222 (43%), Gaps = 3/222 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + L F L +L+ L L N L I AF+ L + L++N L + + F
Sbjct: 126 ENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWF 185
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
LE + I N+V + +F L +L+ L L+ ++ I + L++L+ L
Sbjct: 186 EMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFY 245
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSN-NNLMSLAGVE 180
DN++ + A E ++N L+ + F N+ L L L+N L+S+
Sbjct: 246 DNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFA 305
Query: 181 FESLKLLRNLDLKEN-ALSQIPDNTFSDCFNLEKLDLSKNKL 221
+L L LD+ N LS I F +E L L+ N L
Sbjct: 306 LVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNAL 347
Score = 58.4 bits (135), Expect = 3e-07
Identities = 36/124 (29%), Positives = 58/124 (46%)
Query: 168 LSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINIT 227
L +N+++ + E L L LDL +N+ S D F L L L +N+L +
Sbjct: 76 LQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDH 135
Query: 228 AFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVK 287
+F G Y + +AFS L NL L+L+ N+ ++ SR + +P L I+
Sbjct: 136 SFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILM 195
Query: 288 LSGN 291
+ GN
Sbjct: 196 IGGN 199
Score = 55.2 bits (127), Expect = 2e-06
Identities = 38/144 (26%), Positives = 64/144 (44%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N + + L L LDLS N+ +F +L L +L L+EN L+++ D++F+
Sbjct: 79 NSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFA 138
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
+L++L L+ N+L I AF G + + F ML NL L + G
Sbjct: 139 GLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGG 198
Query: 267 NMFPSLPSRTLDYMPKLTIVKLSG 290
N ++ + L + L+G
Sbjct: 199 NKVDAILDMNFRPLANLRSLVLAG 222
>AL159161-1|CAI17102.1| 754|Homo sapiens relaxin/insulin-like
family peptide receptor 2 protein.
Length = 754
Score = 101 bits (242), Expect = 3e-20
Identities = 70/239 (29%), Positives = 108/239 (45%), Gaps = 1/239 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N +++LP+K+F T L+ I + +N + ++ +F GL +LQIL L+ N I ++
Sbjct: 142 LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLR 201
Query: 107 NGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
G F L L L L DN I IS F N L+ +P Q+ + L +
Sbjct: 202 PGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNW 261
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
+DL N + L F S L L L N + +P+ TFS NL +LDLS N + ++
Sbjct: 262 VDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELS 321
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
F +H F LK L +L L+ P++ +R M L+
Sbjct: 322 PHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLS 380
Score = 95.1 bits (226), Expect = 2e-18
Identities = 62/191 (32%), Positives = 93/191 (48%), Gaps = 1/191 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L GIF+ L L L L N + I FT LF + + NNYL LP+++ A
Sbjct: 195 NCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCA 254
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+ NR+ Y+ + +FL SL +L L +N+I + TF SLKNL L LS
Sbjct: 255 QMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSS 314
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N I +S + F++ N L + F +LK L LDL + ++ F+
Sbjct: 315 NTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQ 374
Query: 183 SLKLLRNLDLK 193
+K L ++ K
Sbjct: 375 PMKNLSHIYFK 385
Score = 93.9 bits (223), Expect = 6e-18
Identities = 63/227 (27%), Positives = 109/227 (48%), Gaps = 1/227 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + LP +F LK + LQ N + I +AF L + L++N + TL +F
Sbjct: 147 NKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFK 206
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
+ L + + +N + + F GL SL L + N ++ + + + L + L
Sbjct: 207 DLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEG 266
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I ++++ F + RN++ +P + F++LK L LDLS+N + L+ F+
Sbjct: 267 NRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFK 326
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
LKLL+ L+L N L + N F L+ LDL + ++ IN F
Sbjct: 327 DLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMF 373
Score = 84.6 bits (200), Expect = 3e-15
Identities = 59/212 (27%), Positives = 98/212 (46%), Gaps = 1/212 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + ++ F L NL+ L L N + + F +L + L +N + + ++LF
Sbjct: 171 NCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFT 230
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L + + NN + +P + L +DL N+I+ + N TF S +L +L L
Sbjct: 231 GLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPR 290
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I + + F + N + + LF +LK L L+LS+N LM L +FE
Sbjct: 291 NQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFE 350
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKL 214
SLK L++LDL+ + I F NL +
Sbjct: 351 SLKQLQSLDLERIEIPNINTRMFQPMKNLSHI 382
Score = 75.4 bits (177), Expect = 2e-12
Identities = 52/176 (29%), Positives = 80/176 (45%), Gaps = 1/176 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + + +F L +L L + NYLE + + +L VDL N + L F
Sbjct: 218 DNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTF 277
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
+ L + + N++ +VP +F L +L LDLS N I + F LK LQ L LS
Sbjct: 278 LSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLS 337
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
N + + N FE+ +R ++ NI T++F +K L + N S A
Sbjct: 338 SNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHIYFKNFRYCSYA 393
Score = 70.5 bits (165), Expect = 6e-11
Identities = 67/243 (27%), Positives = 103/243 (42%), Gaps = 29/243 (11%)
Query: 51 NNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI-QNGT 109
N L ++P + +NN L + + N++ +P F+ L+ + L N I++I +
Sbjct: 126 NGDLKSVP--MISNNVTL--LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAF 181
Query: 110 FSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLS 169
F L NLQIL L+ N I + F++ D N + I +LF L L FL +
Sbjct: 182 FGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMV 241
Query: 170 NNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
NN L +L + L +DL+ N + + ++TF C +L L L +N++ F
Sbjct: 242 NNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGF------ 295
Query: 230 YGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLS 289
V K FS LKNL L L N L + L + LS
Sbjct: 296 ------------------VPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLS 337
Query: 290 GNP 292
NP
Sbjct: 338 SNP 340
Score = 62.1 bits (144), Expect = 2e-08
Identities = 41/135 (30%), Positives = 68/135 (50%), Gaps = 1/135 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
M +N++E LP + + L + L+ N ++ + + F S L + L N + +PEK
Sbjct: 240 MVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEK 299
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILK 119
F++ L +D+S+N + + F L LQ L+LS N + + F SLK LQ L
Sbjct: 300 TFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLD 359
Query: 120 LSDNKINNISDNAFE 134
L +I NI+ F+
Sbjct: 360 LERIEIPNINTRMFQ 374
>AL138708-1|CAH73785.1| 754|Homo sapiens relaxin/insulin-like
family peptide receptor 2 protein.
Length = 754
Score = 101 bits (242), Expect = 3e-20
Identities = 70/239 (29%), Positives = 108/239 (45%), Gaps = 1/239 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N +++LP+K+F T L+ I + +N + ++ +F GL +LQIL L+ N I ++
Sbjct: 142 LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLR 201
Query: 107 NGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
G F L L L L DN I IS F N L+ +P Q+ + L +
Sbjct: 202 PGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNW 261
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
+DL N + L F S L L L N + +P+ TFS NL +LDLS N + ++
Sbjct: 262 VDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELS 321
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
F +H F LK L +L L+ P++ +R M L+
Sbjct: 322 PHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLS 380
Score = 95.1 bits (226), Expect = 2e-18
Identities = 62/191 (32%), Positives = 93/191 (48%), Gaps = 1/191 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L GIF+ L L L L N + I FT LF + + NNYL LP+++ A
Sbjct: 195 NCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCA 254
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+ NR+ Y+ + +FL SL +L L +N+I + TF SLKNL L LS
Sbjct: 255 QMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSS 314
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N I +S + F++ N L + F +LK L LDL + ++ F+
Sbjct: 315 NTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQ 374
Query: 183 SLKLLRNLDLK 193
+K L ++ K
Sbjct: 375 PMKNLSHIYFK 385
Score = 93.9 bits (223), Expect = 6e-18
Identities = 63/227 (27%), Positives = 109/227 (48%), Gaps = 1/227 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + LP +F LK + LQ N + I +AF L + L++N + TL +F
Sbjct: 147 NKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFK 206
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
+ L + + +N + + F GL SL L + N ++ + + + L + L
Sbjct: 207 DLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEG 266
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I ++++ F + RN++ +P + F++LK L LDLS+N + L+ F+
Sbjct: 267 NRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFK 326
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
LKLL+ L+L N L + N F L+ LDL + ++ IN F
Sbjct: 327 DLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMF 373
Score = 84.6 bits (200), Expect = 3e-15
Identities = 59/212 (27%), Positives = 98/212 (46%), Gaps = 1/212 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + ++ F L NL+ L L N + + F +L + L +N + + ++LF
Sbjct: 171 NCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFT 230
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L + + NN + +P + L +DL N+I+ + N TF S +L +L L
Sbjct: 231 GLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPR 290
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I + + F + N + + LF +LK L L+LS+N LM L +FE
Sbjct: 291 NQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFE 350
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKL 214
SLK L++LDL+ + I F NL +
Sbjct: 351 SLKQLQSLDLERIEIPNINTRMFQPMKNLSHI 382
Score = 75.4 bits (177), Expect = 2e-12
Identities = 52/176 (29%), Positives = 80/176 (45%), Gaps = 1/176 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + + +F L +L L + NYLE + + +L VDL N + L F
Sbjct: 218 DNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTF 277
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
+ L + + N++ +VP +F L +L LDLS N I + F LK LQ L LS
Sbjct: 278 LSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLS 337
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
N + + N FE+ +R ++ NI T++F +K L + N S A
Sbjct: 338 SNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHIYFKNFRYCSYA 393
Score = 70.5 bits (165), Expect = 6e-11
Identities = 67/243 (27%), Positives = 103/243 (42%), Gaps = 29/243 (11%)
Query: 51 NNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI-QNGT 109
N L ++P + +NN L + + N++ +P F+ L+ + L N I++I +
Sbjct: 126 NGDLKSVP--MISNNVTL--LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAF 181
Query: 110 FSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLS 169
F L NLQIL L+ N I + F++ D N + I +LF L L FL +
Sbjct: 182 FGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMV 241
Query: 170 NNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
NN L +L + L +DL+ N + + ++TF C +L L L +N++ F
Sbjct: 242 NNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGF------ 295
Query: 230 YGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLS 289
V K FS LKNL L L N L + L + LS
Sbjct: 296 ------------------VPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLS 337
Query: 290 GNP 292
NP
Sbjct: 338 SNP 340
Score = 62.1 bits (144), Expect = 2e-08
Identities = 41/135 (30%), Positives = 68/135 (50%), Gaps = 1/135 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
M +N++E LP + + L + L+ N ++ + + F S L + L N + +PEK
Sbjct: 240 MVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEK 299
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILK 119
F++ L +D+S+N + + F L LQ L+LS N + + F SLK LQ L
Sbjct: 300 TFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLD 359
Query: 120 LSDNKINNISDNAFE 134
L +I NI+ F+
Sbjct: 360 LERIEIPNINTRMFQ 374
>AF453828-1|AAL73946.1| 754|Homo sapiens G protein-coupled receptor
affecting testicular descent protein.
Length = 754
Score = 101 bits (242), Expect = 3e-20
Identities = 70/239 (29%), Positives = 108/239 (45%), Gaps = 1/239 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N +++LP+K+F T L+ I + +N + ++ +F GL +LQIL L+ N I ++
Sbjct: 142 LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLR 201
Query: 107 NGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
G F L L L L DN I IS F N L+ +P Q+ + L +
Sbjct: 202 PGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNW 261
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
+DL N + L F S L L L N + +P+ TFS NL +LDLS N + ++
Sbjct: 262 VDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELS 321
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
F +H F LK L +L L+ P++ +R M L+
Sbjct: 322 PHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLS 380
Score = 95.1 bits (226), Expect = 2e-18
Identities = 62/191 (32%), Positives = 93/191 (48%), Gaps = 1/191 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L GIF+ L L L L N + I FT LF + + NNYL LP+++ A
Sbjct: 195 NCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCA 254
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+ NR+ Y+ + +FL SL +L L +N+I + TF SLKNL L LS
Sbjct: 255 QMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSS 314
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N I +S + F++ N L + F +LK L LDL + ++ F+
Sbjct: 315 NTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQ 374
Query: 183 SLKLLRNLDLK 193
+K L ++ K
Sbjct: 375 PMKNLSHIYFK 385
Score = 93.9 bits (223), Expect = 6e-18
Identities = 63/227 (27%), Positives = 109/227 (48%), Gaps = 1/227 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + LP +F LK + LQ N + I +AF L + L++N + TL +F
Sbjct: 147 NKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFK 206
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
+ L + + +N + + F GL SL L + N ++ + + + L + L
Sbjct: 207 DLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEG 266
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I ++++ F + RN++ +P + F++LK L LDLS+N + L+ F+
Sbjct: 267 NRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFK 326
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
LKLL+ L+L N L + N F L+ LDL + ++ IN F
Sbjct: 327 DLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMF 373
Score = 84.6 bits (200), Expect = 3e-15
Identities = 59/212 (27%), Positives = 98/212 (46%), Gaps = 1/212 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + ++ F L NL+ L L N + + F +L + L +N + + ++LF
Sbjct: 171 NCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFT 230
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L + + NN + +P + L +DL N+I+ + N TF S +L +L L
Sbjct: 231 GLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPR 290
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I + + F + N + + LF +LK L L+LS+N LM L +FE
Sbjct: 291 NQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFE 350
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKL 214
SLK L++LDL+ + I F NL +
Sbjct: 351 SLKQLQSLDLERIEIPNINTRMFQPMKNLSHI 382
Score = 75.4 bits (177), Expect = 2e-12
Identities = 52/176 (29%), Positives = 80/176 (45%), Gaps = 1/176 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + + +F L +L L + NYLE + + +L VDL N + L F
Sbjct: 218 DNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTF 277
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
+ L + + N++ +VP +F L +L LDLS N I + F LK LQ L LS
Sbjct: 278 LSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLS 337
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
N + + N FE+ +R ++ NI T++F +K L + N S A
Sbjct: 338 SNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHIYFKNFRYCSYA 393
Score = 70.5 bits (165), Expect = 6e-11
Identities = 67/243 (27%), Positives = 103/243 (42%), Gaps = 29/243 (11%)
Query: 51 NNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI-QNGT 109
N L ++P + +NN L + + N++ +P F+ L+ + L N I++I +
Sbjct: 126 NGDLKSVP--MISNNVTL--LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAF 181
Query: 110 FSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLS 169
F L NLQIL L+ N I + F++ D N + I +LF L L FL +
Sbjct: 182 FGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMV 241
Query: 170 NNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
NN L +L + L +DL+ N + + ++TF C +L L L +N++ F
Sbjct: 242 NNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGF------ 295
Query: 230 YGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLS 289
V K FS LKNL L L N L + L + LS
Sbjct: 296 ------------------VPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLS 337
Query: 290 GNP 292
NP
Sbjct: 338 SNP 340
Score = 62.1 bits (144), Expect = 2e-08
Identities = 41/135 (30%), Positives = 68/135 (50%), Gaps = 1/135 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
M +N++E LP + + L + L+ N ++ + + F S L + L N + +PEK
Sbjct: 240 MVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEK 299
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILK 119
F++ L +D+S+N + + F L LQ L+LS N + + F SLK LQ L
Sbjct: 300 TFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLD 359
Query: 120 LSDNKINNISDNAFE 134
L +I NI+ F+
Sbjct: 360 LERIEIPNINTRMFQ 374
>AF403384-1|AAL69324.2| 754|Homo sapiens LGR8 protein.
Length = 754
Score = 101 bits (242), Expect = 3e-20
Identities = 70/239 (29%), Positives = 108/239 (45%), Gaps = 1/239 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N +++LP+K+F T L+ I + +N + ++ +F GL +LQIL L+ N I ++
Sbjct: 142 LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLR 201
Query: 107 NGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
G F L L L L DN I IS F N L+ +P Q+ + L +
Sbjct: 202 PGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNW 261
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
+DL N + L F S L L L N + +P+ TFS NL +LDLS N + ++
Sbjct: 262 VDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELS 321
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
F +H F LK L +L L+ P++ +R M L+
Sbjct: 322 PHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLS 380
Score = 95.1 bits (226), Expect = 2e-18
Identities = 62/191 (32%), Positives = 93/191 (48%), Gaps = 1/191 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L GIF+ L L L L N + I FT LF + + NNYL LP+++ A
Sbjct: 195 NCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCA 254
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+ NR+ Y+ + +FL SL +L L +N+I + TF SLKNL L LS
Sbjct: 255 QMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSS 314
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N I +S + F++ N L + F +LK L LDL + ++ F+
Sbjct: 315 NTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQ 374
Query: 183 SLKLLRNLDLK 193
+K L ++ K
Sbjct: 375 PMKNLSHIYFK 385
Score = 93.9 bits (223), Expect = 6e-18
Identities = 63/227 (27%), Positives = 109/227 (48%), Gaps = 1/227 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + LP +F LK + LQ N + I +AF L + L++N + TL +F
Sbjct: 147 NKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFK 206
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
+ L + + +N + + F GL SL L + N ++ + + + L + L
Sbjct: 207 DLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEG 266
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I ++++ F + RN++ +P + F++LK L LDLS+N + L+ F+
Sbjct: 267 NRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFK 326
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
LKLL+ L+L N L + N F L+ LDL + ++ IN F
Sbjct: 327 DLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMF 373
Score = 84.6 bits (200), Expect = 3e-15
Identities = 59/212 (27%), Positives = 98/212 (46%), Gaps = 1/212 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + ++ F L NL+ L L N + + F +L + L +N + + ++LF
Sbjct: 171 NCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFT 230
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L + + NN + +P + L +DL N+I+ + N TF S +L +L L
Sbjct: 231 GLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPR 290
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I + + F + N + + LF +LK L L+LS+N LM L +FE
Sbjct: 291 NQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFE 350
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKL 214
SLK L++LDL+ + I F NL +
Sbjct: 351 SLKQLQSLDLERIEIPNINTRMFQPMKNLSHI 382
Score = 75.4 bits (177), Expect = 2e-12
Identities = 52/176 (29%), Positives = 80/176 (45%), Gaps = 1/176 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + + +F L +L L + NYLE + + +L VDL N + L F
Sbjct: 218 DNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTF 277
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
+ L + + N++ +VP +F L +L LDLS N I + F LK LQ L LS
Sbjct: 278 LSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLS 337
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
N + + N FE+ +R ++ NI T++F +K L + N S A
Sbjct: 338 SNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHIYFKNFRYCSYA 393
Score = 70.5 bits (165), Expect = 6e-11
Identities = 67/243 (27%), Positives = 103/243 (42%), Gaps = 29/243 (11%)
Query: 51 NNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI-QNGT 109
N L ++P + +NN L + + N++ +P F+ L+ + L N I++I +
Sbjct: 126 NGDLKSVP--MISNNVTL--LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAF 181
Query: 110 FSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLS 169
F L NLQIL L+ N I + F++ D N + I +LF L L FL +
Sbjct: 182 FGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMV 241
Query: 170 NNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
NN L +L + L +DL+ N + + ++TF C +L L L +N++ F
Sbjct: 242 NNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGF------ 295
Query: 230 YGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLS 289
V K FS LKNL L L N L + L + LS
Sbjct: 296 ------------------VPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLS 337
Query: 290 GNP 292
NP
Sbjct: 338 SNP 340
Score = 62.1 bits (144), Expect = 2e-08
Identities = 41/135 (30%), Positives = 68/135 (50%), Gaps = 1/135 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
M +N++E LP + + L + L+ N ++ + + F S L + L N + +PEK
Sbjct: 240 MVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEK 299
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILK 119
F++ L +D+S+N + + F L LQ L+LS N + + F SLK LQ L
Sbjct: 300 TFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLD 359
Query: 120 LSDNKINNISDNAFE 134
L +I NI+ F+
Sbjct: 360 LERIEIPNINTRMFQ 374
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 101 bits (241), Expect = 4e-20
Identities = 81/316 (25%), Positives = 136/316 (43%), Gaps = 7/316 (2%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTS-TKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNN 76
+ LK L L N + ++ F + L + L+ N + +P K+F L+ ++++ N
Sbjct: 167 LQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQ-LQHLELNRN 225
Query: 77 RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFEN 135
++ V +F GL +L+ L + +N + + +G F L N++IL+L N + I+
Sbjct: 226 KIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYG 285
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
+N + I + + L LDL+ N+L L F L LL L + N
Sbjct: 286 LLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNN 345
Query: 196 ALSQIPDNTFSDCFNLEKLDLSKNKLRFI---NITAFYGXXXXXXXXXXXXXXYEVHFKA 252
+S I D F +L+ LDL N++ + AF G + KA
Sbjct: 346 RVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKA 405
Query: 253 FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMK 312
F+ L L L L N SL M KL + L+ + CDC ++ WV N +
Sbjct: 406 FTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQ 465
Query: 313 IWDYSPTCVSPWYLEG 328
+ + +C P L+G
Sbjct: 466 SF-VNASCAHPQLLKG 480
Score = 91.9 bits (218), Expect = 2e-17
Identities = 68/270 (25%), Positives = 120/270 (44%), Gaps = 4/270 (1%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
L L N L I + + + + L V L+NN L T+P L + + + ++ NR+V +
Sbjct: 79 LDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEIL 137
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFEN-XXXXXX 141
+ SL+ LDLS N I +Q F L+ L L+ N++ ++ F+N
Sbjct: 138 PEHLKEFQSLETLDLSSNNISELQT-AFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLV 196
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
+RN++ IP ++F L L L+L+ N + ++ G+ F+ L L++L ++ N ++++
Sbjct: 197 LKLNRNRISAIPPKMF-KLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLM 255
Query: 202 DNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT 261
D F N+E L L N L I YG + A+ + L+
Sbjct: 256 DGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSE 315
Query: 262 LYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L L N L + + L + + N
Sbjct: 316 LDLTFNHLSRLDDSSFLGLSLLNTLHIGNN 345
Score = 87.0 bits (206), Expect = 6e-16
Identities = 73/266 (27%), Positives = 119/266 (44%), Gaps = 4/266 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N +E +P + N+ L L N + EI E + L +DLS+N + L
Sbjct: 107 NNELETIPN-LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFP 165
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYS-LQILDLSKNKIQNIQNGTFSLKNLQILKLS 121
A L+ + +++NRV + F L + L +L L++N+I I F L LQ L+L+
Sbjct: 166 ALQ--LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELN 223
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
NKI N+ F+ RN + + F L + L L +NNL +
Sbjct: 224 RNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWL 283
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXX 241
L +L+ L L +NA+++I + + C L +LDL+ N L ++ ++F G
Sbjct: 284 YGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIG 343
Query: 242 XXXXYEVHFKAFSMLKNLTTLYLDGN 267
+ AF L +L TL L N
Sbjct: 344 NNRVSYIADCAFRGLSSLKTLDLKNN 369
Score = 83.8 bits (198), Expect = 6e-15
Identities = 55/175 (31%), Positives = 88/175 (50%), Gaps = 4/175 (2%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ + G L+ L+ L L +N + I +A+ +KL +DL+ N+L L + F
Sbjct: 273 NNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFL 332
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQ---NIQNGTFS-LKNLQILK 119
+ L T+ I NNRV Y+ +F GL SL+ LDL N+I NG FS L L+ L
Sbjct: 333 GLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLI 392
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLM 174
L N+I +I+ AF N + ++ F+ +K L L L+ ++L+
Sbjct: 393 LQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLL 447
Score = 69.7 bits (163), Expect = 1e-10
Identities = 64/246 (26%), Positives = 111/246 (45%), Gaps = 7/246 (2%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+D S L LPE L +++ +D+S+NR+ ++ + S L SL+ + L+ N+++ I
Sbjct: 58 LDCSRKRLARLPEPL---PSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIP 114
Query: 107 NGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFL 166
N N+ +L L+ N+I I + N + + T F L+ L +L
Sbjct: 115 NLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQT-AFPALQ-LKYL 172
Query: 167 DLSNNNLMSLAGVEFESL-KLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
L++N + S+ F++L L L L N +S IP F L+ L+L++NK++ ++
Sbjct: 173 YLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVD 231
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
F G ++ AF L N+ L LD N + L + L
Sbjct: 232 GLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQE 291
Query: 286 VKLSGN 291
+ LS N
Sbjct: 292 LHLSQN 297
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 101 bits (241), Expect = 4e-20
Identities = 81/316 (25%), Positives = 136/316 (43%), Gaps = 7/316 (2%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTS-TKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNN 76
+ LK L L N + ++ F + L + L+ N + +P K+F L+ ++++ N
Sbjct: 167 LQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQ-LQHLELNRN 225
Query: 77 RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFEN 135
++ V +F GL +L+ L + +N + + +G F L N++IL+L N + I+
Sbjct: 226 KIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYG 285
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
+N + I + + L LDL+ N+L L F L LL L + N
Sbjct: 286 LLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNN 345
Query: 196 ALSQIPDNTFSDCFNLEKLDLSKNKLRFI---NITAFYGXXXXXXXXXXXXXXYEVHFKA 252
+S I D F +L+ LDL N++ + AF G + KA
Sbjct: 346 RVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKA 405
Query: 253 FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMK 312
F+ L L L L N SL M KL + L+ + CDC ++ WV N +
Sbjct: 406 FTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQ 465
Query: 313 IWDYSPTCVSPWYLEG 328
+ + +C P L+G
Sbjct: 466 SF-VNASCAHPQLLKG 480
Score = 91.9 bits (218), Expect = 2e-17
Identities = 68/270 (25%), Positives = 120/270 (44%), Gaps = 4/270 (1%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
L L N L I + + + + L V L+NN L T+P L + + + ++ NR+V +
Sbjct: 79 LDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEIL 137
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFEN-XXXXXX 141
+ SL+ LDLS N I +Q F L+ L L+ N++ ++ F+N
Sbjct: 138 PEHLKEFQSLETLDLSSNNISELQT-AFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLV 196
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
+RN++ IP ++F L L L+L+ N + ++ G+ F+ L L++L ++ N ++++
Sbjct: 197 LKLNRNRISAIPPKMF-KLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLM 255
Query: 202 DNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT 261
D F N+E L L N L I YG + A+ + L+
Sbjct: 256 DGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSE 315
Query: 262 LYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L L N L + + L + + N
Sbjct: 316 LDLTFNHLSRLDDSSFLGLSLLNTLHIGNN 345
Score = 87.0 bits (206), Expect = 6e-16
Identities = 73/266 (27%), Positives = 119/266 (44%), Gaps = 4/266 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N +E +P + N+ L L N + EI E + L +DLS+N + L
Sbjct: 107 NNELETIPN-LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFP 165
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYS-LQILDLSKNKIQNIQNGTFSLKNLQILKLS 121
A L+ + +++NRV + F L + L +L L++N+I I F L LQ L+L+
Sbjct: 166 ALQ--LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELN 223
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
NKI N+ F+ RN + + F L + L L +NNL +
Sbjct: 224 RNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWL 283
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXX 241
L +L+ L L +NA+++I + + C L +LDL+ N L ++ ++F G
Sbjct: 284 YGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIG 343
Query: 242 XXXXYEVHFKAFSMLKNLTTLYLDGN 267
+ AF L +L TL L N
Sbjct: 344 NNRVSYIADCAFRGLSSLKTLDLKNN 369
Score = 83.8 bits (198), Expect = 6e-15
Identities = 55/175 (31%), Positives = 88/175 (50%), Gaps = 4/175 (2%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ + G L+ L+ L L +N + I +A+ +KL +DL+ N+L L + F
Sbjct: 273 NNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFL 332
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQ---NIQNGTFS-LKNLQILK 119
+ L T+ I NNRV Y+ +F GL SL+ LDL N+I NG FS L L+ L
Sbjct: 333 GLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLI 392
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLM 174
L N+I +I+ AF N + ++ F+ +K L L L+ ++L+
Sbjct: 393 LQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLL 447
Score = 69.7 bits (163), Expect = 1e-10
Identities = 64/246 (26%), Positives = 111/246 (45%), Gaps = 7/246 (2%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+D S L LPE L +++ +D+S+NR+ ++ + S L SL+ + L+ N+++ I
Sbjct: 58 LDCSRKRLARLPEPL---PSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIP 114
Query: 107 NGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFL 166
N N+ +L L+ N+I I + N + + T F L+ L +L
Sbjct: 115 NLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQT-AFPALQ-LKYL 172
Query: 167 DLSNNNLMSLAGVEFESL-KLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
L++N + S+ F++L L L L N +S IP F L+ L+L++NK++ ++
Sbjct: 173 YLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVD 231
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
F G ++ AF L N+ L LD N + L + L
Sbjct: 232 GLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQE 291
Query: 286 VKLSGN 291
+ LS N
Sbjct: 292 LHLSQN 297
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 101 bits (241), Expect = 4e-20
Identities = 81/316 (25%), Positives = 136/316 (43%), Gaps = 7/316 (2%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTS-TKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNN 76
+ LK L L N + ++ F + L + L+ N + +P K+F L+ ++++ N
Sbjct: 167 LQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQ-LQHLELNRN 225
Query: 77 RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFEN 135
++ V +F GL +L+ L + +N + + +G F L N++IL+L N + I+
Sbjct: 226 KIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYG 285
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
+N + I + + L LDL+ N+L L F L LL L + N
Sbjct: 286 LLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNN 345
Query: 196 ALSQIPDNTFSDCFNLEKLDLSKNKLRFI---NITAFYGXXXXXXXXXXXXXXYEVHFKA 252
+S I D F +L+ LDL N++ + AF G + KA
Sbjct: 346 RVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKA 405
Query: 253 FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMK 312
F+ L L L L N SL M KL + L+ + CDC ++ WV N +
Sbjct: 406 FTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQ 465
Query: 313 IWDYSPTCVSPWYLEG 328
+ + +C P L+G
Sbjct: 466 SF-VNASCAHPQLLKG 480
Score = 91.9 bits (218), Expect = 2e-17
Identities = 68/270 (25%), Positives = 120/270 (44%), Gaps = 4/270 (1%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
L L N L I + + + + L V L+NN L T+P L + + + ++ NR+V +
Sbjct: 79 LDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEIL 137
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFEN-XXXXXX 141
+ SL+ LDLS N I +Q F L+ L L+ N++ ++ F+N
Sbjct: 138 PEHLKEFQSLETLDLSSNNISELQT-AFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLV 196
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
+RN++ IP ++F L L L+L+ N + ++ G+ F+ L L++L ++ N ++++
Sbjct: 197 LKLNRNRISAIPPKMF-KLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLM 255
Query: 202 DNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT 261
D F N+E L L N L I YG + A+ + L+
Sbjct: 256 DGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSE 315
Query: 262 LYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L L N L + + L + + N
Sbjct: 316 LDLTFNHLSRLDDSSFLGLSLLNTLHIGNN 345
Score = 87.0 bits (206), Expect = 6e-16
Identities = 73/266 (27%), Positives = 119/266 (44%), Gaps = 4/266 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N +E +P + N+ L L N + EI E + L +DLS+N + L
Sbjct: 107 NNELETIPN-LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFP 165
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYS-LQILDLSKNKIQNIQNGTFSLKNLQILKLS 121
A L+ + +++NRV + F L + L +L L++N+I I F L LQ L+L+
Sbjct: 166 ALQ--LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELN 223
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
NKI N+ F+ RN + + F L + L L +NNL +
Sbjct: 224 RNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWL 283
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXX 241
L +L+ L L +NA+++I + + C L +LDL+ N L ++ ++F G
Sbjct: 284 YGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIG 343
Query: 242 XXXXYEVHFKAFSMLKNLTTLYLDGN 267
+ AF L +L TL L N
Sbjct: 344 NNRVSYIADCAFRGLSSLKTLDLKNN 369
Score = 83.8 bits (198), Expect = 6e-15
Identities = 55/175 (31%), Positives = 88/175 (50%), Gaps = 4/175 (2%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ + G L+ L+ L L +N + I +A+ +KL +DL+ N+L L + F
Sbjct: 273 NNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFL 332
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQ---NIQNGTFS-LKNLQILK 119
+ L T+ I NNRV Y+ +F GL SL+ LDL N+I NG FS L L+ L
Sbjct: 333 GLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLI 392
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLM 174
L N+I +I+ AF N + ++ F+ +K L L L+ ++L+
Sbjct: 393 LQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLL 447
Score = 69.7 bits (163), Expect = 1e-10
Identities = 64/246 (26%), Positives = 111/246 (45%), Gaps = 7/246 (2%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+D S L LPE L +++ +D+S+NR+ ++ + S L SL+ + L+ N+++ I
Sbjct: 58 LDCSRKRLARLPEPL---PSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIP 114
Query: 107 NGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFL 166
N N+ +L L+ N+I I + N + + T F L+ L +L
Sbjct: 115 NLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQT-AFPALQ-LKYL 172
Query: 167 DLSNNNLMSLAGVEFESL-KLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
L++N + S+ F++L L L L N +S IP F L+ L+L++NK++ ++
Sbjct: 173 YLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVD 231
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
F G ++ AF L N+ L LD N + L + L
Sbjct: 232 GLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQE 291
Query: 286 VKLSGN 291
+ LS N
Sbjct: 292 LHLSQN 297
>AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.
Length = 1059
Score = 101 bits (241), Expect = 4e-20
Identities = 81/316 (25%), Positives = 136/316 (43%), Gaps = 7/316 (2%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTS-TKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNN 76
+ LK L L N + ++ F + L + L+ N + +P K+F L+ ++++ N
Sbjct: 107 LQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQ-LQHLELNRN 165
Query: 77 RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFEN 135
++ V +F GL +L+ L + +N + + +G F L N++IL+L N + I+
Sbjct: 166 KIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYG 225
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
+N + I + + L LDL+ N+L L F L LL L + N
Sbjct: 226 LLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNN 285
Query: 196 ALSQIPDNTFSDCFNLEKLDLSKNKLRFI---NITAFYGXXXXXXXXXXXXXXYEVHFKA 252
+S I D F +L+ LDL N++ + AF G + KA
Sbjct: 286 RVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKA 345
Query: 253 FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMK 312
F+ L L L L N SL M KL + L+ + CDC ++ WV N +
Sbjct: 346 FTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQ 405
Query: 313 IWDYSPTCVSPWYLEG 328
+ + +C P L+G
Sbjct: 406 SF-VNASCAHPQLLKG 420
Score = 91.1 bits (216), Expect = 4e-17
Identities = 67/268 (25%), Positives = 119/268 (44%), Gaps = 4/268 (1%)
Query: 25 LQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSD 84
L N L I + + + + L V L+NN L T+P L + + + ++ NR+V + +
Sbjct: 21 LSHNRLSFIKASSMSHLQSLREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEILPE 79
Query: 85 SFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFEN-XXXXXXXX 143
SL+ LDLS N I +Q F L+ L L+ N++ ++ F+N
Sbjct: 80 HLKEFQSLETLDLSSNNISELQT-AFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLK 138
Query: 144 XDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDN 203
+RN++ IP ++F L L L+L+ N + ++ G+ F+ L L++L ++ N ++++ D
Sbjct: 139 LNRNRISAIPPKMF-KLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDG 197
Query: 204 TFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLY 263
F N+E L L N L I YG + A+ + L+ L
Sbjct: 198 AFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELD 257
Query: 264 LDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L N L + + L + + N
Sbjct: 258 LTFNHLSRLDDSSFLGLSLLNTLHIGNN 285
Score = 87.0 bits (206), Expect = 6e-16
Identities = 73/266 (27%), Positives = 119/266 (44%), Gaps = 4/266 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N +E +P + N+ L L N + EI E + L +DLS+N + L
Sbjct: 47 NNELETIPN-LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFP 105
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYS-LQILDLSKNKIQNIQNGTFSLKNLQILKLS 121
A L+ + +++NRV + F L + L +L L++N+I I F L LQ L+L+
Sbjct: 106 ALQ--LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELN 163
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
NKI N+ F+ RN + + F L + L L +NNL +
Sbjct: 164 RNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWL 223
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXX 241
L +L+ L L +NA+++I + + C L +LDL+ N L ++ ++F G
Sbjct: 224 YGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIG 283
Query: 242 XXXXYEVHFKAFSMLKNLTTLYLDGN 267
+ AF L +L TL L N
Sbjct: 284 NNRVSYIADCAFRGLSSLKTLDLKNN 309
Score = 83.8 bits (198), Expect = 6e-15
Identities = 55/175 (31%), Positives = 88/175 (50%), Gaps = 4/175 (2%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ + G L+ L+ L L +N + I +A+ +KL +DL+ N+L L + F
Sbjct: 213 NNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFL 272
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQ---NIQNGTFS-LKNLQILK 119
+ L T+ I NNRV Y+ +F GL SL+ LDL N+I NG FS L L+ L
Sbjct: 273 GLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLI 332
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLM 174
L N+I +I+ AF N + ++ F+ +K L L L+ ++L+
Sbjct: 333 LQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLL 387
Score = 64.1 bits (149), Expect = 5e-09
Identities = 57/221 (25%), Positives = 99/221 (44%), Gaps = 4/221 (1%)
Query: 72 DISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDN 131
D+S+NR+ ++ + S L SL+ + L+ N+++ I N N+ +L L+ N+I I
Sbjct: 20 DLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPE 79
Query: 132 AFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESL-KLLRNL 190
+ N + + T F L+ L +L L++N + S+ F++L L L
Sbjct: 80 HLKEFQSLETLDLSSNNISELQT-AFPALQ-LKYLYLNSNRVTSMEPGYFDNLANTLLVL 137
Query: 191 DLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHF 250
L N +S IP F L+ L+L++NK++ ++ F G ++
Sbjct: 138 KLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMD 196
Query: 251 KAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
AF L N+ L LD N + L + L + LS N
Sbjct: 197 GAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQN 237
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 101 bits (241), Expect = 4e-20
Identities = 81/316 (25%), Positives = 136/316 (43%), Gaps = 7/316 (2%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTS-TKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNN 76
+ LK L L N + ++ F + L + L+ N + +P K+F L+ ++++ N
Sbjct: 167 LQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQ-LQHLELNRN 225
Query: 77 RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFEN 135
++ V +F GL +L+ L + +N + + +G F L N++IL+L N + I+
Sbjct: 226 KIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYG 285
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
+N + I + + L LDL+ N+L L F L LL L + N
Sbjct: 286 LLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNN 345
Query: 196 ALSQIPDNTFSDCFNLEKLDLSKNKLRFI---NITAFYGXXXXXXXXXXXXXXYEVHFKA 252
+S I D F +L+ LDL N++ + AF G + KA
Sbjct: 346 RVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKA 405
Query: 253 FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMK 312
F+ L L L L N SL M KL + L+ + CDC ++ WV N +
Sbjct: 406 FTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQ 465
Query: 313 IWDYSPTCVSPWYLEG 328
+ + +C P L+G
Sbjct: 466 SF-VNASCAHPQLLKG 480
Score = 91.9 bits (218), Expect = 2e-17
Identities = 68/270 (25%), Positives = 120/270 (44%), Gaps = 4/270 (1%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
L L N L I + + + + L V L+NN L T+P L + + + ++ NR+V +
Sbjct: 79 LDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEIL 137
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFEN-XXXXXX 141
+ SL+ LDLS N I +Q F L+ L L+ N++ ++ F+N
Sbjct: 138 PEHLKEFQSLETLDLSSNNISELQT-AFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLV 196
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
+RN++ IP ++F L L L+L+ N + ++ G+ F+ L L++L ++ N ++++
Sbjct: 197 LKLNRNRISAIPPKMF-KLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLM 255
Query: 202 DNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT 261
D F N+E L L N L I YG + A+ + L+
Sbjct: 256 DGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSE 315
Query: 262 LYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L L N L + + L + + N
Sbjct: 316 LDLTFNHLSRLDDSSFLGLSLLNTLHIGNN 345
Score = 87.0 bits (206), Expect = 6e-16
Identities = 73/266 (27%), Positives = 119/266 (44%), Gaps = 4/266 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N +E +P + N+ L L N + EI E + L +DLS+N + L
Sbjct: 107 NNELETIPN-LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFP 165
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYS-LQILDLSKNKIQNIQNGTFSLKNLQILKLS 121
A L+ + +++NRV + F L + L +L L++N+I I F L LQ L+L+
Sbjct: 166 ALQ--LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELN 223
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
NKI N+ F+ RN + + F L + L L +NNL +
Sbjct: 224 RNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWL 283
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXX 241
L +L+ L L +NA+++I + + C L +LDL+ N L ++ ++F G
Sbjct: 284 YGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIG 343
Query: 242 XXXXYEVHFKAFSMLKNLTTLYLDGN 267
+ AF L +L TL L N
Sbjct: 344 NNRVSYIADCAFRGLSSLKTLDLKNN 369
Score = 83.8 bits (198), Expect = 6e-15
Identities = 55/175 (31%), Positives = 88/175 (50%), Gaps = 4/175 (2%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ + G L+ L+ L L +N + I +A+ +KL +DL+ N+L L + F
Sbjct: 273 NNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFL 332
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQ---NIQNGTFS-LKNLQILK 119
+ L T+ I NNRV Y+ +F GL SL+ LDL N+I NG FS L L+ L
Sbjct: 333 GLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLI 392
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLM 174
L N+I +I+ AF N + ++ F+ +K L L L+ ++L+
Sbjct: 393 LQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLL 447
Score = 69.7 bits (163), Expect = 1e-10
Identities = 64/246 (26%), Positives = 111/246 (45%), Gaps = 7/246 (2%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+D S L LPE L +++ +D+S+NR+ ++ + S L SL+ + L+ N+++ I
Sbjct: 58 LDCSRKRLARLPEPL---PSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIP 114
Query: 107 NGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFL 166
N N+ +L L+ N+I I + N + + T F L+ L +L
Sbjct: 115 NLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQT-AFPALQ-LKYL 172
Query: 167 DLSNNNLMSLAGVEFESL-KLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
L++N + S+ F++L L L L N +S IP F L+ L+L++NK++ ++
Sbjct: 173 YLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVD 231
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
F G ++ AF L N+ L LD N + L + L
Sbjct: 232 GLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQE 291
Query: 286 VKLSGN 291
+ LS N
Sbjct: 292 LHLSQN 297
>AY899851-1|AAX85199.1| 730|Homo sapiens LGR8.1 protein.
Length = 730
Score = 100 bits (240), Expect = 5e-20
Identities = 66/236 (27%), Positives = 107/236 (45%), Gaps = 1/236 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N +++LP+K+F T L+ I + +N + ++ +F GL +LQIL L+ N I ++
Sbjct: 142 LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLR 201
Query: 107 NGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
G F L L L L DN I IS F N L+ +P Q+ + L +
Sbjct: 202 PGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNW 261
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
+DL N + L F S L LDL N ++++ + F D L+KL+LS N L +++
Sbjct: 262 VDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLH 321
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMP 281
F ++ + F +KNL+ +Y + S MP
Sbjct: 322 KNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHIYFKNFRYCSYAPHVRICMP 377
Score = 95.1 bits (226), Expect = 2e-18
Identities = 59/175 (33%), Positives = 85/175 (48%), Gaps = 1/175 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L GIF+ L L L L N + I FT LF + + NNYL LP+++ A
Sbjct: 195 NCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCA 254
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+ NR+ Y+ + +FL SL +LDLS N I + F LK LQ L LS
Sbjct: 255 QMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITELSPHLFKDLKLLQKLNLSS 314
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
N + + N FE+ +R ++ NI T++F +K L + N S A
Sbjct: 315 NPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHIYFKNFRYCSYA 369
Score = 82.2 bits (194), Expect = 2e-14
Identities = 63/235 (26%), Positives = 104/235 (44%), Gaps = 5/235 (2%)
Query: 51 NNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI-QNGT 109
N L ++P + +NN L + + N++ +P F+ L+ + L N I++I +
Sbjct: 126 NGDLKSVP--MISNNVTL--LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAF 181
Query: 110 FSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLS 169
F L NLQIL L+ N I + F++ D N + I +LF L L FL +
Sbjct: 182 FGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMV 241
Query: 170 NNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
NN L +L + L +DL+ N + + ++TF C +L LDLS N + ++ F
Sbjct: 242 NNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITELSPHLF 301
Query: 230 YGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
+H F LK L +L L+ P++ +R M L+
Sbjct: 302 KDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLS 356
Score = 81.8 bits (193), Expect = 2e-14
Identities = 58/212 (27%), Positives = 98/212 (46%), Gaps = 1/212 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + LP +F LK + LQ N + I +AF L + L++N + TL +F
Sbjct: 147 NKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFK 206
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
+ L + + +N + + F GL SL L + N ++ + + + L + L
Sbjct: 207 DLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEG 266
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I ++++ F + N + + LF +LK L L+LS+N LM L +FE
Sbjct: 267 NRIKYLTNSTFLSCDSLTVLDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFE 326
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKL 214
SLK L++LDL+ + I F NL +
Sbjct: 327 SLKQLQSLDLERIEIPNINTRMFQPMKNLSHI 358
Score = 61.3 bits (142), Expect = 4e-08
Identities = 36/116 (31%), Positives = 63/116 (54%), Gaps = 1/116 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
M +N++E LP + + L + L+ N ++ + + F S L +DLS+N + L
Sbjct: 240 MVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITELSPH 299
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNL 115
LF + L+ +++S+N ++Y+ + F L LQ LDL + +I NI F +KNL
Sbjct: 300 LFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNL 355
Score = 60.5 bits (140), Expect = 6e-08
Identities = 41/133 (30%), Positives = 62/133 (46%), Gaps = 1/133 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + + +F L +L L + NYLE + + +L VDL N + L F
Sbjct: 218 DNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTF 277
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
+ L +D+S+N + + F L LQ L+LS N + + F SLK LQ L L
Sbjct: 278 LSCDSLTVLDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLE 337
Query: 122 DNKINNISDNAFE 134
+I NI+ F+
Sbjct: 338 RIEIPNINTRMFQ 350
Score = 42.3 bits (95), Expect = 0.018
Identities = 45/187 (24%), Positives = 73/187 (39%), Gaps = 10/187 (5%)
Query: 149 LKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDC 208
LK++P + NN+ L L N + SL F L+ + L+ N + I F
Sbjct: 129 LKSVP-MISNNVT---LLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGL 184
Query: 209 FNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNM 268
NL+ L L+ N + + F + + F+ L +L L + N
Sbjct: 185 CNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNY 244
Query: 269 FPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG 328
+LP + MP+L V L GN L S ++ + + + D S ++ L
Sbjct: 245 LEALPKQMCAQMPQLNWVDLEGN----RIKYLTNSTFLSCDSLTVLDLSSNTITE--LSP 298
Query: 329 HFLKKLK 335
H K LK
Sbjct: 299 HLFKDLK 305
>AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein.
Length = 606
Score = 100 bits (240), Expect = 5e-20
Identities = 86/323 (26%), Positives = 143/323 (44%), Gaps = 29/323 (8%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + + G F +L NL++LRL+ N L+ + FT L +D+S N + L + +F
Sbjct: 90 DNIIANVEPGAFNNLFNLRSLRLKGNRLKLVPLGVFTGLSNLTKLDISENKIVILLDYMF 149
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
+ L+++++ +N +VY+ +F GL SL+ L L K + + S L++L L L
Sbjct: 150 QDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLK 209
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKN-IPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
INN+ AF+ D L + +P L L L ++N NL ++ +
Sbjct: 210 HLNINNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGLN-LTSLSVTNTNLSTVPFLA 268
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXX 240
F+ L L +L+L N +S I FSD L++L + +LR I +F G
Sbjct: 269 FKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQG--------- 319
Query: 241 XXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHAL 300
L+ L L + N+ +L L ++ ++ NP CDC L
Sbjct: 320 ---------------LRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPLACDCRLL 364
Query: 301 YISAWVRLNEMKIWDYSPTCVSP 323
+I R ++ P C P
Sbjct: 365 WILQ--RQPTLQFGGQQPMCAGP 385
Score = 77.0 bits (181), Expect = 7e-13
Identities = 58/198 (29%), Positives = 89/198 (44%), Gaps = 3/198 (1%)
Query: 93 QILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN 151
+ILDLSKN+++++ F S L+ + LSDN I N+ AF N N+LK
Sbjct: 60 KILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKL 119
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNL 211
+P +F L L LD+S N ++ L F+ L L++L++ +N L I FS +L
Sbjct: 120 VPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSL 179
Query: 212 EKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPS 271
E+L L K L + A + AF L +L L +D +P
Sbjct: 180 EQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEID--YWPL 237
Query: 272 LPSRTLDYMPKLTIVKLS 289
L + + L + LS
Sbjct: 238 LDMMPANSLYGLNLTSLS 255
>AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat
neuronal 6C protein.
Length = 606
Score = 100 bits (240), Expect = 5e-20
Identities = 86/323 (26%), Positives = 143/323 (44%), Gaps = 29/323 (8%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + + G F +L NL++LRL+ N L+ + FT L +D+S N + L + +F
Sbjct: 90 DNIIANVEPGAFNNLFNLRSLRLKGNRLKLVPLGVFTGLSNLTKLDISENKIVILLDYMF 149
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
+ L+++++ +N +VY+ +F GL SL+ L L K + + S L++L L L
Sbjct: 150 QDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLK 209
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKN-IPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
INN+ AF+ D L + +P L L L ++N NL ++ +
Sbjct: 210 HLNINNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGLN-LTSLSVTNTNLSTVPFLA 268
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXX 240
F+ L L +L+L N +S I FSD L++L + +LR I +F G
Sbjct: 269 FKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQG--------- 319
Query: 241 XXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHAL 300
L+ L L + N+ +L L ++ ++ NP CDC L
Sbjct: 320 ---------------LRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPLACDCRLL 364
Query: 301 YISAWVRLNEMKIWDYSPTCVSP 323
+I R ++ P C P
Sbjct: 365 WILQ--RQPTLQFGGQQPMCAGP 385
Score = 77.0 bits (181), Expect = 7e-13
Identities = 58/198 (29%), Positives = 89/198 (44%), Gaps = 3/198 (1%)
Query: 93 QILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN 151
+ILDLSKN+++++ F S L+ + LSDN I N+ AF N N+LK
Sbjct: 60 KILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKL 119
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNL 211
+P +F L L LD+S N ++ L F+ L L++L++ +N L I FS +L
Sbjct: 120 VPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSL 179
Query: 212 EKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPS 271
E+L L K L + A + AF L +L L +D +P
Sbjct: 180 EQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEID--YWPL 237
Query: 272 LPSRTLDYMPKLTIVKLS 289
L + + L + LS
Sbjct: 238 LDMMPANSLYGLNLTSLS 255
>AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens
cDNA FLJ31810 fis, clone NT2RI2009289, weakly similar to
CARBOXYPEPTIDASE N 83 KD CHAIN. ).
Length = 606
Score = 100 bits (240), Expect = 5e-20
Identities = 86/323 (26%), Positives = 143/323 (44%), Gaps = 29/323 (8%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + + G F +L NL++LRL+ N L+ + FT L +D+S N + L + +F
Sbjct: 90 DNIIANVEPGAFNNLFNLRSLRLKGNRLKLVPLGVFTGLSNLTKLDISENKIVILLDYMF 149
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
+ L+++++ +N +VY+ +F GL SL+ L L K + + S L++L L L
Sbjct: 150 QDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLK 209
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKN-IPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
INN+ AF+ D L + +P L L L ++N NL ++ +
Sbjct: 210 HLNINNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGLN-LTSLSVTNTNLSTVPFLA 268
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXX 240
F+ L L +L+L N +S I FSD L++L + +LR I +F G
Sbjct: 269 FKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQG--------- 319
Query: 241 XXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHAL 300
L+ L L + N+ +L L ++ ++ NP CDC L
Sbjct: 320 ---------------LRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPLACDCRLL 364
Query: 301 YISAWVRLNEMKIWDYSPTCVSP 323
+I R ++ P C P
Sbjct: 365 WILQ--RQPTLQFGGQQPMCAGP 385
Score = 77.0 bits (181), Expect = 7e-13
Identities = 58/198 (29%), Positives = 89/198 (44%), Gaps = 3/198 (1%)
Query: 93 QILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN 151
+ILDLSKN+++++ F S L+ + LSDN I N+ AF N N+LK
Sbjct: 60 KILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKL 119
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNL 211
+P +F L L LD+S N ++ L F+ L L++L++ +N L I FS +L
Sbjct: 120 VPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSL 179
Query: 212 EKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPS 271
E+L L K L + A + AF L +L L +D +P
Sbjct: 180 EQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEID--YWPL 237
Query: 272 LPSRTLDYMPKLTIVKLS 289
L + + L + LS
Sbjct: 238 LDMMPANSLYGLNLTSLS 255
>AJ297858-1|CAC82651.1| 649|Homo sapiens hypothetical protein
protein.
Length = 649
Score = 100 bits (239), Expect = 6e-20
Identities = 77/280 (27%), Positives = 128/280 (45%), Gaps = 11/280 (3%)
Query: 54 LYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-L 112
L +P+ + +N +L ++ N + + +D+F L+ L++L L +N I+ I+ G F+ L
Sbjct: 66 LSEVPQGIPSNTRYLNLME---NNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGL 122
Query: 113 KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSN-N 171
+L L+L DN + I AFE N +++IP+ FN + L+ LDL
Sbjct: 123 ASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELK 182
Query: 172 NLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
L ++ FE L L+ L+L + +P+ T LE+L++S N I +F+G
Sbjct: 183 KLEYISEGAFEGLFNLKYLNLGMCNIKDMPNLT--PLVGLEELEMSGNHFPEIRPGSFHG 240
Query: 232 XXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
AF L +L L L N SLP + L + L N
Sbjct: 241 LSSLKKLWVMNSHERN----AFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHN 296
Query: 292 PWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFL 331
PW+CDC L+++ W+R C +P ++ G +L
Sbjct: 297 PWNCDCDILWLAWWLREYIPTNSTCCGRCHAPMHMRGRYL 336
Score = 67.7 bits (158), Expect = 4e-10
Identities = 59/221 (26%), Positives = 101/221 (45%), Gaps = 8/221 (3%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N+++ + F L +L+ L+L RN + +I+ AF L ++L +N+L +P
Sbjct: 82 LMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSG 141
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSK-NKIQNIQNGTF-SLKNLQIL 118
F + L + + NN + +PS +F + SL LDL + K++ I G F L NL+ L
Sbjct: 142 AFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYL 201
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
L I ++ + N I F+ L L L + N++ +
Sbjct: 202 NLGMCNIKDMPN--LTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSHERN--- 256
Query: 179 VEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
F+ L L L+L N LS +P + F+ L +L L N
Sbjct: 257 -AFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHN 296
>BC073974-1|AAH73974.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 97.1 bits (231), Expect = 6e-19
Identities = 64/220 (29%), Positives = 110/220 (50%), Gaps = 2/220 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N+ L F ++ NL +L LQ + E+ + AF K+L ++ LS+N + L F
Sbjct: 61 NNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFD 120
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ T L + + +N+V +P L +L IL L+ NKI+ ++ G F K+L+ L LS+
Sbjct: 121 DLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSE 180
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N ++++ A ++ DRN+L + P+ + L+ + L LS+N L S+ F+
Sbjct: 181 NALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQ 240
Query: 183 SL-KLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
S + L L L L + D F L+ + L N+L
Sbjct: 241 SFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRL 280
Score = 82.6 bits (195), Expect = 1e-14
Identities = 74/288 (25%), Positives = 112/288 (38%), Gaps = 7/288 (2%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L N L F L ++ + + ++ V + +F GL L L LS N I+ ++
Sbjct: 56 LNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLR 115
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
G F L L L L NK+ + + NK++ + F K L +
Sbjct: 116 AGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRW 175
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
L LS N L SL + ++ L + N LS P S +E+L LS N L+ I
Sbjct: 176 LYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIP 235
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFK-AFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
AF E AF + L ++L+ N LPS L
Sbjct: 236 DNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSNF--PFDSLE 293
Query: 285 IVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLK 332
+ L+ NPW C C + W+ E K TC SP +G ++
Sbjct: 294 TLALTNNPWKCTCQLRGLRRWL---EAKASRPDATCASPAKFKGQHIR 338
Score = 69.7 bits (163), Expect = 1e-10
Identities = 47/177 (26%), Positives = 76/177 (42%)
Query: 116 QILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMS 175
++L L N ++ N+F +++ + F LK LI+L LS+N++
Sbjct: 54 KLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRV 113
Query: 176 LAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXX 235
L F+ L L L L N ++++P S NL L L+ NK+R + AF G
Sbjct: 114 LRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDL 173
Query: 236 XXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNP 292
+ A ++NL ++D N S PS L + + +KLS NP
Sbjct: 174 RWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNP 230
Score = 53.6 bits (123), Expect = 7e-06
Identities = 31/122 (25%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + L G + + NL + RN L S A + + + + LS+N L ++P+ F
Sbjct: 180 ENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAF 239
Query: 63 AN-NTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLS 121
+ +LET+ + N + +FLG+ +L+ + L N++ + + F +L+ L L+
Sbjct: 240 QSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPS-NFPFDSLETLALT 298
Query: 122 DN 123
+N
Sbjct: 299 NN 300
>BC036360-1|AAH36360.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 97.1 bits (231), Expect = 6e-19
Identities = 64/220 (29%), Positives = 110/220 (50%), Gaps = 2/220 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N+ L F ++ NL +L LQ + E+ + AF K+L ++ LS+N + L F
Sbjct: 61 NNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFD 120
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ T L + + +N+V +P L +L IL L+ NKI+ ++ G F K+L+ L LS+
Sbjct: 121 DLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSE 180
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N ++++ A ++ DRN+L + P+ + L+ + L LS+N L S+ F+
Sbjct: 181 NALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQ 240
Query: 183 SL-KLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
S + L L L L + D F L+ + L N+L
Sbjct: 241 SFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRL 280
Score = 82.6 bits (195), Expect = 1e-14
Identities = 74/288 (25%), Positives = 112/288 (38%), Gaps = 7/288 (2%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L N L F L ++ + + ++ V + +F GL L L LS N I+ ++
Sbjct: 56 LNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLR 115
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
G F L L L L NK+ + + NK++ + F K L +
Sbjct: 116 AGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRW 175
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
L LS N L SL + ++ L + N LS P S +E+L LS N L+ I
Sbjct: 176 LYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIP 235
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFK-AFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
AF E AF + L ++L+ N LPS L
Sbjct: 236 DNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSNF--PFDSLE 293
Query: 285 IVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLK 332
+ L+ NPW C C + W+ E K TC SP +G ++
Sbjct: 294 TLALTNNPWKCTCQLRGLRRWL---EAKASRPDATCASPAKFKGQHIR 338
Score = 69.7 bits (163), Expect = 1e-10
Identities = 47/177 (26%), Positives = 76/177 (42%)
Query: 116 QILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMS 175
++L L N ++ N+F +++ + F LK LI+L LS+N++
Sbjct: 54 KLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRV 113
Query: 176 LAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXX 235
L F+ L L L L N ++++P S NL L L+ NK+R + AF G
Sbjct: 114 LRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDL 173
Query: 236 XXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNP 292
+ A ++NL ++D N S PS L + + +KLS NP
Sbjct: 174 RWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNP 230
Score = 53.6 bits (123), Expect = 7e-06
Identities = 31/122 (25%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + L G + + NL + RN L S A + + + + LS+N L ++P+ F
Sbjct: 180 ENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAF 239
Query: 63 AN-NTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLS 121
+ +LET+ + N + +FLG+ +L+ + L N++ + + F +L+ L L+
Sbjct: 240 QSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPS-NFPFDSLETLALT 298
Query: 122 DN 123
+N
Sbjct: 299 NN 300
>AF371328-1|AAK51556.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 97.1 bits (231), Expect = 6e-19
Identities = 64/220 (29%), Positives = 110/220 (50%), Gaps = 2/220 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N+ L F ++ NL +L LQ + E+ + AF K+L ++ LS+N + L F
Sbjct: 61 NNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFD 120
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ T L + + +N+V +P L +L IL L+ NKI+ ++ G F K+L+ L LS+
Sbjct: 121 DLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSE 180
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N ++++ A ++ DRN+L + P+ + L+ + L LS+N L S+ F+
Sbjct: 181 NALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQ 240
Query: 183 SL-KLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
S + L L L L + D F L+ + L N+L
Sbjct: 241 SFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRL 280
Score = 82.6 bits (195), Expect = 1e-14
Identities = 74/288 (25%), Positives = 112/288 (38%), Gaps = 7/288 (2%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L N L F L ++ + + ++ V + +F GL L L LS N I+ ++
Sbjct: 56 LNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLR 115
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
G F L L L L NK+ + + NK++ + F K L +
Sbjct: 116 AGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRW 175
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
L LS N L SL + ++ L + N LS P S +E+L LS N L+ I
Sbjct: 176 LYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIP 235
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFK-AFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
AF E AF + L ++L+ N LPS L
Sbjct: 236 DNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSNF--PFDSLE 293
Query: 285 IVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLK 332
+ L+ NPW C C + W+ E K TC SP +G ++
Sbjct: 294 TLALTNNPWKCTCQLRGLRRWL---EAKASRPDATCASPAKFKGQHIR 338
Score = 69.7 bits (163), Expect = 1e-10
Identities = 47/177 (26%), Positives = 76/177 (42%)
Query: 116 QILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMS 175
++L L N ++ N+F +++ + F LK LI+L LS+N++
Sbjct: 54 KLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRV 113
Query: 176 LAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXX 235
L F+ L L L L N ++++P S NL L L+ NK+R + AF G
Sbjct: 114 LRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDL 173
Query: 236 XXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNP 292
+ A ++NL ++D N S PS L + + +KLS NP
Sbjct: 174 RWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNP 230
Score = 53.6 bits (123), Expect = 7e-06
Identities = 31/122 (25%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + L G + + NL + RN L S A + + + + LS+N L ++P+ F
Sbjct: 180 ENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAF 239
Query: 63 AN-NTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLS 121
+ +LET+ + N + +FLG+ +L+ + L N++ + + F +L+ L L+
Sbjct: 240 QSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPS-NFPFDSLETLALT 298
Query: 122 DN 123
+N
Sbjct: 299 NN 300
>BC113717-1|AAI13718.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 96.7 bits (230), Expect = 8e-19
Identities = 78/312 (25%), Positives = 131/312 (41%), Gaps = 4/312 (1%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N L L F L + + +N + + ++F G+ L+ L LS N+I
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
N TF + NL+ L LS N+++++ F N L+ IP ++F + + L
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
LDL N + SLA F + L+ L L+ N S++ F +L+ L L NK+ I
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKA-FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
T + + F + NL L LD N + LD L
Sbjct: 246 QTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLN 305
Query: 285 IVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG-HFLKKLKFPELCAGQ 343
+ L+GN W C + + W++ + + + + C SP L+G + + +K +C
Sbjct: 306 DISLAGNIWECSRNICSLVNWLK-SFKGLRENTIICASPKELQGVNVIDAVKNYSICGKS 364
Query: 344 WASMVNLSPRLP 355
+L+ LP
Sbjct: 365 TTERFDLARALP 376
Score = 87.8 bits (208), Expect = 4e-16
Identities = 63/223 (28%), Positives = 100/223 (44%), Gaps = 2/223 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ L F+ L L L L N++ ID AF ++L + LS+N + F
Sbjct: 71 NSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFR 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
T L +D+S N++ + S+ F GL L L L N ++ I F +NL++L L
Sbjct: 131 PVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGY 190
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I +++ N F + N+ + LF L L L L N + +
Sbjct: 191 NRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSW 250
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCF-NLEKLDLSKNKLRFI 224
+ L+ LDL N + + C NL++L+L NKL FI
Sbjct: 251 TWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFI 293
Score = 69.7 bits (163), Expect = 1e-10
Identities = 52/194 (26%), Positives = 85/194 (43%), Gaps = 2/194 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + Y F + NL+ L L N L + SE F +KL + L +N L T+P ++F
Sbjct: 119 NRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQ 178
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ LE +D+ NR+ + + F G+ L+ L L N+ + F L +LQ L L
Sbjct: 179 DCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQW 238
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIP-TQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
NKI+ I N+++ +F + L L+L +N L +
Sbjct: 239 NKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEIL 298
Query: 182 ESLKLLRNLDLKEN 195
+S L ++ L N
Sbjct: 299 DSWISLNDISLAGN 312
>BC113715-1|AAI13716.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 96.7 bits (230), Expect = 8e-19
Identities = 78/312 (25%), Positives = 131/312 (41%), Gaps = 4/312 (1%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N L L F L + + +N + + ++F G+ L+ L LS N+I
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
N TF + NL+ L LS N+++++ F N L+ IP ++F + + L
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
LDL N + SLA F + L+ L L+ N S++ F +L+ L L NK+ I
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKA-FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
T + + F + NL L LD N + LD L
Sbjct: 246 QTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLN 305
Query: 285 IVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG-HFLKKLKFPELCAGQ 343
+ L+GN W C + + W++ + + + + C SP L+G + + +K +C
Sbjct: 306 DISLAGNIWECSRNICSLVNWLK-SFKGLRENTIICASPKELQGVNVIDAVKNYSICGKS 364
Query: 344 WASMVNLSPRLP 355
+L+ LP
Sbjct: 365 TTERFDLARALP 376
Score = 87.8 bits (208), Expect = 4e-16
Identities = 63/223 (28%), Positives = 100/223 (44%), Gaps = 2/223 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ L F+ L L L L N++ ID AF ++L + LS+N + F
Sbjct: 71 NSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFR 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
T L +D+S N++ + S+ F GL L L L N ++ I F +NL++L L
Sbjct: 131 PVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGY 190
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I +++ N F + N+ + LF L L L L N + +
Sbjct: 191 NRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSW 250
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCF-NLEKLDLSKNKLRFI 224
+ L+ LDL N + + C NL++L+L NKL FI
Sbjct: 251 TWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFI 293
Score = 69.7 bits (163), Expect = 1e-10
Identities = 52/194 (26%), Positives = 85/194 (43%), Gaps = 2/194 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + Y F + NL+ L L N L + SE F +KL + L +N L T+P ++F
Sbjct: 119 NRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQ 178
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ LE +D+ NR+ + + F G+ L+ L L N+ + F L +LQ L L
Sbjct: 179 DCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQW 238
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIP-TQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
NKI+ I N+++ +F + L L+L +N L +
Sbjct: 239 NKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEIL 298
Query: 182 ESLKLLRNLDLKEN 195
+S L ++ L N
Sbjct: 299 DSWISLNDISLAGN 312
>BC111492-1|AAI11493.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 96.7 bits (230), Expect = 8e-19
Identities = 78/312 (25%), Positives = 131/312 (41%), Gaps = 4/312 (1%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N L L F L + + +N + + ++F G+ L+ L LS N+I
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
N TF + NL+ L LS N+++++ F N L+ IP ++F + + L
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
LDL N + SLA F + L+ L L+ N S++ F +L+ L L NK+ I
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKA-FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
T + + F + NL L LD N + LD L
Sbjct: 246 QTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLN 305
Query: 285 IVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG-HFLKKLKFPELCAGQ 343
+ L+GN W C + + W++ + + + + C SP L+G + + +K +C
Sbjct: 306 DISLAGNIWECSRNICSLVNWLK-SFKGLRENTIICASPKELQGVNVIDAVKNYSICGKS 364
Query: 344 WASMVNLSPRLP 355
+L+ LP
Sbjct: 365 TTERFDLARALP 376
Score = 87.8 bits (208), Expect = 4e-16
Identities = 63/223 (28%), Positives = 100/223 (44%), Gaps = 2/223 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ L F+ L L L L N++ ID AF ++L + LS+N + F
Sbjct: 71 NSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFR 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
T L +D+S N++ + S+ F GL L L L N ++ I F +NL++L L
Sbjct: 131 PVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGY 190
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I +++ N F + N+ + LF L L L L N + +
Sbjct: 191 NRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSW 250
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCF-NLEKLDLSKNKLRFI 224
+ L+ LDL N + + C NL++L+L NKL FI
Sbjct: 251 TWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFI 293
Score = 69.7 bits (163), Expect = 1e-10
Identities = 52/194 (26%), Positives = 85/194 (43%), Gaps = 2/194 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + Y F + NL+ L L N L + SE F +KL + L +N L T+P ++F
Sbjct: 119 NRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQ 178
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ LE +D+ NR+ + + F G+ L+ L L N+ + F L +LQ L L
Sbjct: 179 DCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQW 238
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIP-TQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
NKI+ I N+++ +F + L L+L +N L +
Sbjct: 239 NKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEIL 298
Query: 182 ESLKLLRNLDLKEN 195
+S L ++ L N
Sbjct: 299 DSWISLNDISLAGN 312
>AY358315-1|AAQ88681.1| 513|Homo sapiens GFNV803 protein.
Length = 513
Score = 96.7 bits (230), Expect = 8e-19
Identities = 78/312 (25%), Positives = 131/312 (41%), Gaps = 4/312 (1%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N L L F L + + +N + + ++F G+ L+ L LS N+I
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
N TF + NL+ L LS N+++++ F N L+ IP ++F + + L
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
LDL N + SLA F + L+ L L+ N S++ F +L+ L L NK+ I
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKA-FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
T + + F + NL L LD N + LD L
Sbjct: 246 QTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLN 305
Query: 285 IVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG-HFLKKLKFPELCAGQ 343
+ L+GN W C + + W++ + + + + C SP L+G + + +K +C
Sbjct: 306 DISLAGNIWECSRNICSLVNWLK-SFKGLRENTIICASPKELQGVNVIDAVKNYSICGKS 364
Query: 344 WASMVNLSPRLP 355
+L+ LP
Sbjct: 365 TTERFDLARALP 376
Score = 87.8 bits (208), Expect = 4e-16
Identities = 63/223 (28%), Positives = 100/223 (44%), Gaps = 2/223 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ L F+ L L L L N++ ID AF ++L + LS+N + F
Sbjct: 71 NSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFR 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
T L +D+S N++ + S+ F GL L L L N ++ I F +NL++L L
Sbjct: 131 PVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGY 190
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I +++ N F + N+ + LF L L L L N + +
Sbjct: 191 NRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSW 250
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCF-NLEKLDLSKNKLRFI 224
+ L+ LDL N + + C NL++L+L NKL FI
Sbjct: 251 TWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFI 293
Score = 69.7 bits (163), Expect = 1e-10
Identities = 52/194 (26%), Positives = 85/194 (43%), Gaps = 2/194 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + Y F + NL+ L L N L + SE F +KL + L +N L T+P ++F
Sbjct: 119 NRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQ 178
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ LE +D+ NR+ + + F G+ L+ L L N+ + F L +LQ L L
Sbjct: 179 DCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQW 238
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIP-TQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
NKI+ I N+++ +F + L L+L +N L +
Sbjct: 239 NKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEIL 298
Query: 182 ESLKLLRNLDLKEN 195
+S L ++ L N
Sbjct: 299 DSWISLNDISLAGN 312
>AY182028-1|AAO67549.1| 513|Homo sapiens leucine-rich repeat
transmembrane neuronal 3 protein protein.
Length = 513
Score = 96.7 bits (230), Expect = 8e-19
Identities = 78/312 (25%), Positives = 131/312 (41%), Gaps = 4/312 (1%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N L L F L + + +N + + ++F G+ L+ L LS N+I
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
N TF + NL+ L LS N+++++ F N L+ IP ++F + + L
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
LDL N + SLA F + L+ L L+ N S++ F +L+ L L NK+ I
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKA-FSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
T + + F + NL L LD N + LD L
Sbjct: 246 QTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLN 305
Query: 285 IVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG-HFLKKLKFPELCAGQ 343
+ L+GN W C + + W++ + + + + C SP L+G + + +K +C
Sbjct: 306 DISLAGNIWECSRNICSLVNWLK-SFKGLRENTIICASPKELQGVNVIDAVKNYSICGKS 364
Query: 344 WASMVNLSPRLP 355
+L+ LP
Sbjct: 365 TTERFDLARALP 376
Score = 87.8 bits (208), Expect = 4e-16
Identities = 63/223 (28%), Positives = 100/223 (44%), Gaps = 2/223 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ L F+ L L L L N++ ID AF ++L + LS+N + F
Sbjct: 71 NSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFR 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
T L +D+S N++ + S+ F GL L L L N ++ I F +NL++L L
Sbjct: 131 PVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGY 190
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I +++ N F + N+ + LF L L L L N + +
Sbjct: 191 NRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSW 250
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCF-NLEKLDLSKNKLRFI 224
+ L+ LDL N + + C NL++L+L NKL FI
Sbjct: 251 TWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFI 293
Score = 69.7 bits (163), Expect = 1e-10
Identities = 52/194 (26%), Positives = 85/194 (43%), Gaps = 2/194 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + Y F + NL+ L L N L + SE F +KL + L +N L T+P ++F
Sbjct: 119 NRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQ 178
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ LE +D+ NR+ + + F G+ L+ L L N+ + F L +LQ L L
Sbjct: 179 DCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQW 238
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIP-TQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
NKI+ I N+++ +F + L L+L +N L +
Sbjct: 239 NKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEIL 298
Query: 182 ESLKLLRNLDLKEN 195
+S L ++ L N
Sbjct: 299 DSWISLNDISLAGN 312
>U96769-1|AAC13410.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 95.5 bits (227), Expect = 2e-18
Identities = 63/220 (28%), Positives = 110/220 (50%), Gaps = 2/220 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N+ L F ++ NL +L LQ + E+ + AF K+L ++ LS+N + + F
Sbjct: 61 NNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVVRAGAFD 120
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ T L + + +N+V +P L +L IL L+ NKI+ ++ G F K+L+ L LS+
Sbjct: 121 DLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGPFQGAKDLRWLYLSE 180
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N ++++ A ++ DRN+L + P+ + L+ + L LS+N L S+ F+
Sbjct: 181 NALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQ 240
Query: 183 SL-KLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
S + L L L L + D F L+ + L N+L
Sbjct: 241 SFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRL 280
Score = 82.2 bits (194), Expect = 2e-14
Identities = 74/288 (25%), Positives = 112/288 (38%), Gaps = 7/288 (2%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L N L F L ++ + + ++ V + +F GL L L LS N I+ ++
Sbjct: 56 LNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVVR 115
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
G F L L L L NK+ + + NK++ + F K L +
Sbjct: 116 AGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGPFQGAKDLRW 175
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
L LS N L SL + ++ L + N LS P S +E+L LS N L+ I
Sbjct: 176 LYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIP 235
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFK-AFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
AF E AF + L ++L+ N LPS L
Sbjct: 236 DNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSNF--PFDSLE 293
Query: 285 IVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLK 332
+ L+ NPW C C + W+ E K TC SP +G ++
Sbjct: 294 TLALTNNPWKCTCQLRGLRRWL---EAKASRPDATCASPAKFKGQHIR 338
Score = 66.5 bits (155), Expect = 1e-09
Identities = 45/177 (25%), Positives = 75/177 (42%)
Query: 116 QILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMS 175
++L L N ++ N+F +++ + F LK LI+L LS+N++
Sbjct: 54 KLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRV 113
Query: 176 LAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXX 235
+ F+ L L L L N ++++P S NL L L+ NK+R + F G
Sbjct: 114 VRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGPFQGAKDL 173
Query: 236 XXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNP 292
+ A ++NL ++D N S PS L + + +KLS NP
Sbjct: 174 RWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNP 230
Score = 53.6 bits (123), Expect = 7e-06
Identities = 31/122 (25%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + L G + + NL + RN L S A + + + + LS+N L ++P+ F
Sbjct: 180 ENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAF 239
Query: 63 AN-NTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLS 121
+ +LET+ + N + +FLG+ +L+ + L N++ + + F +L+ L L+
Sbjct: 240 QSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPS-NFPFDSLETLALT 298
Query: 122 DN 123
+N
Sbjct: 299 NN 300
>BC034947-1|AAH34947.1| 716|Homo sapiens leucine rich repeat
neuronal 1 protein.
Length = 716
Score = 95.1 bits (226), Expect = 2e-18
Identities = 74/326 (22%), Positives = 142/326 (43%), Gaps = 10/326 (3%)
Query: 15 ESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDIS 74
+ L NL L +N I + +L + L N + + + + + L+ + I+
Sbjct: 92 QQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYIN 151
Query: 75 NNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAF 133
+N++ + + +F GL +L L L+ NK++ I + F S NL+IL + +N + I D F
Sbjct: 152 HNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNF 211
Query: 134 ENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLK 193
+ L +IP L L L +N L+ + + + + L+ LDL
Sbjct: 212 KPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPSLKFLDLN 271
Query: 194 ENALSQIPDNTFSDCFNLEKLDLSK-NKLRFINITAFYGXXXXXXXXXXXXXXYE-VHFK 251
+N + +I + F + L++L ++ +L ++ A +H
Sbjct: 272 KNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRL 331
Query: 252 AFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEM 311
AF + L +L L+ N ++ +T++ +P L + + NP CDC + W+ N+
Sbjct: 332 AFRSVPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPLRCDC----VIHWINSNKT 387
Query: 312 KIWDYSPT---CVSPWYLEGHFLKKL 334
I P C P +GH +K++
Sbjct: 388 NIRFMEPLSMFCAMPPEYKGHQVKEV 413
Score = 76.2 bits (179), Expect = 1e-12
Identities = 59/222 (26%), Positives = 102/222 (45%), Gaps = 3/222 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + + F L NL L L N L+ IDS F ST L + + N + + + F
Sbjct: 153 NQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFK 212
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI-QNGTFSLKNLQILKLSD 122
L ++ ++ + +P ++ +GL SL+ L NK+ + Q + +L+ L L+
Sbjct: 213 PLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPSLKFLDLNK 272
Query: 123 NKINNISDNAFENXXXXXXXXXDR-NKLKNIPTQLFNNLKCLIFLDLSNNNLMS-LAGVE 180
N I+ I + F+N + +L ++ +NL L L+ +NN +S + +
Sbjct: 273 NPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLA 332
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
F S+ L +L L NAL+ I T NL ++ + N LR
Sbjct: 333 FRSVPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPLR 374
Score = 70.5 bits (165), Expect = 6e-11
Identities = 64/245 (26%), Positives = 103/245 (42%), Gaps = 4/245 (1%)
Query: 50 SNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT 109
SNN T+ E N L +D S N + L L L L +N+I + +
Sbjct: 81 SNNIAKTVDELQQLFN--LTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYC 138
Query: 110 FS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDL 168
L NLQ L ++ N+I+ IS +AF + NKLK I ++ F++ L L +
Sbjct: 139 LQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMI 198
Query: 169 SNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITA 228
N ++ + + F+ L LR+L L L+ IP N +LE L NKL + A
Sbjct: 199 GENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLA 258
Query: 229 FYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG-NMFPSLPSRTLDYMPKLTIVK 287
+++ F + L L ++ S+ LD +P+LT ++
Sbjct: 259 LQKVPSLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLE 318
Query: 288 LSGNP 292
+ NP
Sbjct: 319 ATNNP 323
>AY358312-1|AAQ88679.1| 716|Homo sapiens NLRR protein.
Length = 716
Score = 94.7 bits (225), Expect = 3e-18
Identities = 74/326 (22%), Positives = 142/326 (43%), Gaps = 10/326 (3%)
Query: 15 ESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDIS 74
+ L NL L +N I + +L + L N + + + + + L+ + I+
Sbjct: 92 QQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYIN 151
Query: 75 NNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAF 133
+N++ + + +F GL +L L L+ NK++ I + F S NL+IL + +N + I D F
Sbjct: 152 HNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNF 211
Query: 134 ENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLK 193
+ L +IP L L L +N L+ + + + + L+ LDL
Sbjct: 212 KPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLN 271
Query: 194 ENALSQIPDNTFSDCFNLEKLDLSK-NKLRFINITAFYGXXXXXXXXXXXXXXYE-VHFK 251
+N + +I + F + L++L ++ +L ++ A +H
Sbjct: 272 KNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRL 331
Query: 252 AFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEM 311
AF + L +L L+ N ++ +T++ +P L + + NP CDC + W+ N+
Sbjct: 332 AFRSVPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPLRCDC----VIHWINSNKT 387
Query: 312 KIWDYSPT---CVSPWYLEGHFLKKL 334
I P C P +GH +K++
Sbjct: 388 NIRFMEPLSMFCAMPPEYKGHQVKEV 413
Score = 78.2 bits (184), Expect = 3e-13
Identities = 60/222 (27%), Positives = 102/222 (45%), Gaps = 3/222 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + + F L NL L L N L+ IDS F ST L + + N + + + F
Sbjct: 153 NQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFK 212
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI-QNGTFSLKNLQILKLSD 122
L ++ ++ + +P ++ +GL SL+ L NK+ + Q + NL+ L L+
Sbjct: 213 PLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNK 272
Query: 123 NKINNISDNAFENXXXXXXXXXDR-NKLKNIPTQLFNNLKCLIFLDLSNNNLMS-LAGVE 180
N I+ I + F+N + +L ++ +NL L L+ +NN +S + +
Sbjct: 273 NPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLA 332
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
F S+ L +L L NAL+ I T NL ++ + N LR
Sbjct: 333 FRSVPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPLR 374
Score = 70.1 bits (164), Expect = 8e-11
Identities = 64/245 (26%), Positives = 103/245 (42%), Gaps = 4/245 (1%)
Query: 50 SNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT 109
SNN T+ E N L +D S N + L L L L +N+I + +
Sbjct: 81 SNNIAKTVDELQQLFN--LTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYC 138
Query: 110 FS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDL 168
L NLQ L ++ N+I+ IS +AF + NKLK I ++ F++ L L +
Sbjct: 139 LQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMI 198
Query: 169 SNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITA 228
N ++ + + F+ L LR+L L L+ IP N +LE L NKL + A
Sbjct: 199 GENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLA 258
Query: 229 FYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG-NMFPSLPSRTLDYMPKLTIVK 287
+++ F + L L ++ S+ LD +P+LT ++
Sbjct: 259 LQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLE 318
Query: 288 LSGNP 292
+ NP
Sbjct: 319 ATNNP 323
Score = 39.9 bits (89), Expect = 0.096
Identities = 31/127 (24%), Positives = 62/127 (48%), Gaps = 3/127 (2%)
Query: 2 FDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSN-NYLYTLPEK 60
+DN + +P + + NLK L L +N + +I F + +L + ++N L ++
Sbjct: 247 YDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRY 306
Query: 61 LFANNTFLETIDISNN-RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQIL 118
N L ++ +NN ++ Y+ +F + +L+ L L+ N + I T SL NL+ +
Sbjct: 307 ALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREI 366
Query: 119 KLSDNKI 125
+ N +
Sbjct: 367 SIHSNPL 373
>AB074161-1|BAE45733.1| 716|Homo sapiens neuronal leucine-rich
repeat protein-1 protein.
Length = 716
Score = 94.7 bits (225), Expect = 3e-18
Identities = 74/326 (22%), Positives = 142/326 (43%), Gaps = 10/326 (3%)
Query: 15 ESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDIS 74
+ L NL L +N I + +L + L N + + + + + L+ + I+
Sbjct: 92 QQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYIN 151
Query: 75 NNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAF 133
+N++ + + +F GL +L L L+ NK++ I + F S NL+IL + +N + I D F
Sbjct: 152 HNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNF 211
Query: 134 ENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLK 193
+ L +IP L L L +N L+ + + + + L+ LDL
Sbjct: 212 KPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLN 271
Query: 194 ENALSQIPDNTFSDCFNLEKLDLSK-NKLRFINITAFYGXXXXXXXXXXXXXXYE-VHFK 251
+N + +I + F + L++L ++ +L ++ A +H
Sbjct: 272 KNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRL 331
Query: 252 AFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEM 311
AF + L +L L+ N ++ +T++ +P L + + NP CDC + W+ N+
Sbjct: 332 AFRSVPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPLRCDC----VIHWINSNKT 387
Query: 312 KIWDYSPT---CVSPWYLEGHFLKKL 334
I P C P +GH +K++
Sbjct: 388 NIRFMEPLSMFCAMPPEYKGHQVKEV 413
Score = 78.2 bits (184), Expect = 3e-13
Identities = 60/222 (27%), Positives = 102/222 (45%), Gaps = 3/222 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + + F L NL L L N L+ IDS F ST L + + N + + + F
Sbjct: 153 NQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFK 212
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI-QNGTFSLKNLQILKLSD 122
L ++ ++ + +P ++ +GL SL+ L NK+ + Q + NL+ L L+
Sbjct: 213 PLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNK 272
Query: 123 NKINNISDNAFENXXXXXXXXXDR-NKLKNIPTQLFNNLKCLIFLDLSNNNLMS-LAGVE 180
N I+ I + F+N + +L ++ +NL L L+ +NN +S + +
Sbjct: 273 NPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLA 332
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
F S+ L +L L NAL+ I T NL ++ + N LR
Sbjct: 333 FRSVPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPLR 374
Score = 70.1 bits (164), Expect = 8e-11
Identities = 64/245 (26%), Positives = 103/245 (42%), Gaps = 4/245 (1%)
Query: 50 SNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT 109
SNN T+ E N L +D S N + L L L L +N+I + +
Sbjct: 81 SNNIAKTVDELQQLFN--LTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYC 138
Query: 110 FS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDL 168
L NLQ L ++ N+I+ IS +AF + NKLK I ++ F++ L L +
Sbjct: 139 LQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMI 198
Query: 169 SNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITA 228
N ++ + + F+ L LR+L L L+ IP N +LE L NKL + A
Sbjct: 199 GENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLA 258
Query: 229 FYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG-NMFPSLPSRTLDYMPKLTIVK 287
+++ F + L L ++ S+ LD +P+LT ++
Sbjct: 259 LQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLE 318
Query: 288 LSGNP 292
+ NP
Sbjct: 319 ATNNP 323
Score = 39.9 bits (89), Expect = 0.096
Identities = 31/127 (24%), Positives = 62/127 (48%), Gaps = 3/127 (2%)
Query: 2 FDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSN-NYLYTLPEK 60
+DN + +P + + NLK L L +N + +I F + +L + ++N L ++
Sbjct: 247 YDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRY 306
Query: 61 LFANNTFLETIDISNN-RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQIL 118
N L ++ +NN ++ Y+ +F + +L+ L L+ N + I T SL NL+ +
Sbjct: 307 ALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREI 366
Query: 119 KLSDNKI 125
+ N +
Sbjct: 367 SIHSNPL 373
>AB040930-1|BAA96021.1| 730|Homo sapiens KIAA1497 protein protein.
Length = 730
Score = 94.7 bits (225), Expect = 3e-18
Identities = 74/326 (22%), Positives = 142/326 (43%), Gaps = 10/326 (3%)
Query: 15 ESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDIS 74
+ L NL L +N I + +L + L N + + + + + L+ + I+
Sbjct: 106 QQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYIN 165
Query: 75 NNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAF 133
+N++ + + +F GL +L L L+ NK++ I + F S NL+IL + +N + I D F
Sbjct: 166 HNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNF 225
Query: 134 ENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLK 193
+ L +IP L L L +N L+ + + + + L+ LDL
Sbjct: 226 KPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLN 285
Query: 194 ENALSQIPDNTFSDCFNLEKLDLSK-NKLRFINITAFYGXXXXXXXXXXXXXXYE-VHFK 251
+N + +I + F + L++L ++ +L ++ A +H
Sbjct: 286 KNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRL 345
Query: 252 AFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEM 311
AF + L +L L+ N ++ +T++ +P L + + NP CDC + W+ N+
Sbjct: 346 AFRSVPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPLRCDC----VIHWINSNKT 401
Query: 312 KIWDYSPT---CVSPWYLEGHFLKKL 334
I P C P +GH +K++
Sbjct: 402 NIRFMEPLSMFCAMPPEYKGHQVKEV 427
Score = 78.2 bits (184), Expect = 3e-13
Identities = 60/222 (27%), Positives = 102/222 (45%), Gaps = 3/222 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + + F L NL L L N L+ IDS F ST L + + N + + + F
Sbjct: 167 NQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFK 226
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI-QNGTFSLKNLQILKLSD 122
L ++ ++ + +P ++ +GL SL+ L NK+ + Q + NL+ L L+
Sbjct: 227 PLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNK 286
Query: 123 NKINNISDNAFENXXXXXXXXXDR-NKLKNIPTQLFNNLKCLIFLDLSNNNLMS-LAGVE 180
N I+ I + F+N + +L ++ +NL L L+ +NN +S + +
Sbjct: 287 NPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLA 346
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
F S+ L +L L NAL+ I T NL ++ + N LR
Sbjct: 347 FRSVPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPLR 388
Score = 70.1 bits (164), Expect = 8e-11
Identities = 64/245 (26%), Positives = 103/245 (42%), Gaps = 4/245 (1%)
Query: 50 SNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT 109
SNN T+ E N L +D S N + L L L L +N+I + +
Sbjct: 95 SNNIAKTVDELQQLFN--LTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYC 152
Query: 110 FS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDL 168
L NLQ L ++ N+I+ IS +AF + NKLK I ++ F++ L L +
Sbjct: 153 LQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMI 212
Query: 169 SNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITA 228
N ++ + + F+ L LR+L L L+ IP N +LE L NKL + A
Sbjct: 213 GENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLA 272
Query: 229 FYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG-NMFPSLPSRTLDYMPKLTIVK 287
+++ F + L L ++ S+ LD +P+LT ++
Sbjct: 273 LQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLE 332
Query: 288 LSGNP 292
+ NP
Sbjct: 333 ATNNP 337
Score = 39.9 bits (89), Expect = 0.096
Identities = 31/127 (24%), Positives = 62/127 (48%), Gaps = 3/127 (2%)
Query: 2 FDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSN-NYLYTLPEK 60
+DN + +P + + NLK L L +N + +I F + +L + ++N L ++
Sbjct: 261 YDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRY 320
Query: 61 LFANNTFLETIDISNN-RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQIL 118
N L ++ +NN ++ Y+ +F + +L+ L L+ N + I T SL NL+ +
Sbjct: 321 ALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREI 380
Query: 119 KLSDNKI 125
+ N +
Sbjct: 381 SIHSNPL 387
>BC128608-1|AAI28609.1| 441|Homo sapiens reticulon 4 receptor-like
1 protein.
Length = 441
Score = 94.3 bits (224), Expect = 4e-18
Identities = 76/249 (30%), Positives = 103/249 (41%), Gaps = 6/249 (2%)
Query: 97 LSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXX-DRNKLKNIPTQ 155
L N+I +Q G FS + L + N I I + FE D +L+ + +
Sbjct: 61 LQNNRIGLLQPGHFS-PAMVTLWIYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAPE 119
Query: 156 LFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLD 215
F L L L L L +L F L L+ L L++N + + D+ F D NL L
Sbjct: 120 TFQGLVKLHALYLYKCGLSALPAGVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLF 179
Query: 216 LSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSR 275
L NKL + F G VH KAF L+ LTTL+L N L
Sbjct: 180 LHGNKLWSLGPGTFRGLVNLDRLLLHENQLQWVHHKAFHDLRRLTTLFLFNNSLSELQGE 239
Query: 276 TLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLK 335
L + L ++L+GNPW C C A S W L + + CVSP G LK L+
Sbjct: 240 CLAPLGALEFLRLNGNPWDCGCRAR--SLWEWLQRFRGSSSAVPCVSPGLRHGQDLKLLR 297
Query: 336 FPEL--CAG 342
+ C G
Sbjct: 298 AEDFRNCTG 306
Score = 66.9 bits (156), Expect = 7e-10
Identities = 49/173 (28%), Positives = 78/173 (45%), Gaps = 2/173 (1%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRN-YLEEIDSEAFTSTKKLFHVDLSNNYLYTLPE 59
++ N++ Y+ FE V+L+ L L N L + E F KL + L L LP
Sbjct: 83 IYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAPETFQGLVKLHALYLYKCGLSALPA 142
Query: 60 KLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQIL 118
+F L+ + + +N + Y+ D F+ L +L L L NK+ ++ GTF L NL L
Sbjct: 143 GVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLHGNKLWSLGPGTFRGLVNLDRL 202
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNN 171
L +N++ + AF + N L + + L L FL L+ N
Sbjct: 203 LLHENQLQWVHHKAFHDLRRLTTLFLFNNSLSELQGECLAPLGALEFLRLNGN 255
>AY250219-1|AAP82836.1| 441|Homo sapiens nogo receptor-like 2
protein.
Length = 441
Score = 94.3 bits (224), Expect = 4e-18
Identities = 76/249 (30%), Positives = 103/249 (41%), Gaps = 6/249 (2%)
Query: 97 LSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXX-DRNKLKNIPTQ 155
L N+I +Q G FS + L + N I I + FE D +L+ + +
Sbjct: 61 LQNNRIGLLQPGHFS-PAMVTLWIYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAPE 119
Query: 156 LFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLD 215
F L L L L L +L F L L+ L L++N + + D+ F D NL L
Sbjct: 120 TFQGLVKLHALYLYKCGLSALPAGVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLF 179
Query: 216 LSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSR 275
L NKL + F G VH KAF L+ LTTL+L N L
Sbjct: 180 LHGNKLWSLGPGTFRGLVNLDRLLLHENQLQWVHHKAFHDLRRLTTLFLFNNSLSELQGE 239
Query: 276 TLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLK 335
L + L ++L+GNPW C C A S W L + + CVSP G LK L+
Sbjct: 240 CLAPLGALEFLRLNGNPWDCGCRAR--SLWEWLQRFRGSSSAVPCVSPGLRHGQDLKLLR 297
Query: 336 FPEL--CAG 342
+ C G
Sbjct: 298 AEDFRNCTG 306
Score = 66.9 bits (156), Expect = 7e-10
Identities = 49/173 (28%), Positives = 78/173 (45%), Gaps = 2/173 (1%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRN-YLEEIDSEAFTSTKKLFHVDLSNNYLYTLPE 59
++ N++ Y+ FE V+L+ L L N L + E F KL + L L LP
Sbjct: 83 IYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAPETFQGLVKLHALYLYKCGLSALPA 142
Query: 60 KLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQIL 118
+F L+ + + +N + Y+ D F+ L +L L L NK+ ++ GTF L NL L
Sbjct: 143 GVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLHGNKLWSLGPGTFRGLVNLDRL 202
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNN 171
L +N++ + AF + N L + + L L FL L+ N
Sbjct: 203 LLHENQLQWVHHKAFHDLRRLTTLFLFNNSLSELQGECLAPLGALEFLRLNGN 255
>AF532859-1|AAP21836.1| 441|Homo sapiens Nogo-66 receptor homolog-2
protein.
Length = 441
Score = 94.3 bits (224), Expect = 4e-18
Identities = 76/249 (30%), Positives = 103/249 (41%), Gaps = 6/249 (2%)
Query: 97 LSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXX-DRNKLKNIPTQ 155
L N+I +Q G FS + L + N I I + FE D +L+ + +
Sbjct: 61 LQNNRIGLLQPGHFS-PAMVTLWIYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAPE 119
Query: 156 LFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLD 215
F L L L L L +L F L L+ L L++N + + D+ F D NL L
Sbjct: 120 TFQGLVKLHALYLYKCGLSALPAGVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLF 179
Query: 216 LSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSR 275
L NKL + F G VH KAF L+ LTTL+L N L
Sbjct: 180 LHGNKLWSLGPGTFRGLVNLDRLLLHENQLQWVHHKAFHDLRRLTTLFLFNNSLSELQGE 239
Query: 276 TLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLK 335
L + L ++L+GNPW C C A S W L + + CVSP G LK L+
Sbjct: 240 CLAPLGALEFLRLNGNPWDCGCRAR--SLWEWLQRFRGSSSAVPCVSPGLRHGQDLKLLR 297
Query: 336 FPEL--CAG 342
+ C G
Sbjct: 298 AEDFRNCTG 306
Score = 66.9 bits (156), Expect = 7e-10
Identities = 49/173 (28%), Positives = 78/173 (45%), Gaps = 2/173 (1%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRN-YLEEIDSEAFTSTKKLFHVDLSNNYLYTLPE 59
++ N++ Y+ FE V+L+ L L N L + E F KL + L L LP
Sbjct: 83 IYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAPETFQGLVKLHALYLYKCGLSALPA 142
Query: 60 KLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQIL 118
+F L+ + + +N + Y+ D F+ L +L L L NK+ ++ GTF L NL L
Sbjct: 143 GVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLHGNKLWSLGPGTFRGLVNLDRL 202
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNN 171
L +N++ + AF + N L + + L L FL L+ N
Sbjct: 203 LLHENQLQWVHHKAFHDLRRLTTLFLFNNSLSELQGECLAPLGALEFLRLNGN 255
>BC011057-1|AAH11057.2| 620|Homo sapiens leucine rich repeat and Ig
domain containing 1 protein.
Length = 620
Score = 93.9 bits (223), Expect = 6e-18
Identities = 90/341 (26%), Positives = 147/341 (43%), Gaps = 35/341 (10%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N V + G F +L NL+TL L+ N L+ I FT L +D+S N + L + +F
Sbjct: 104 ENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMF 163
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
+ L+++++ +N +VY+ +F GL SL+ L L K + +I S L L +L+L
Sbjct: 164 QDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLR 223
Query: 122 DNKINNISDNAFENXXXXXXXXXDR-NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
IN I D +F+ L + L L L +++ NL ++ +
Sbjct: 224 HLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLN-LTSLSITHCNLTAVPYLA 282
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXX 240
L LR L+L N +S I + + L+++ L +L + AF G
Sbjct: 283 VRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRG--------- 333
Query: 241 XXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHAL 300
L L L + GN +L + L + L NP CDC L
Sbjct: 334 ---------------LNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPLACDCRLL 378
Query: 301 YI--SAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPEL 339
++ W RLN + PTC +P +++G K FP++
Sbjct: 379 WVFRRRW-RLNFNR---QQPTCATPEFVQGKEFK--DFPDV 413
Score = 80.2 bits (189), Expect = 7e-14
Identities = 78/280 (27%), Positives = 127/280 (45%), Gaps = 11/280 (3%)
Query: 93 QILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN 151
++LDL KN+I+ + F S +L+ L+L++N ++ + AF N N+LK
Sbjct: 74 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 133
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNL 211
IP +F L L LD+S N ++ L F+ L L++L++ +N L I FS +L
Sbjct: 134 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 193
Query: 212 EKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPS 271
E+L L K L I A + +F L L L + + +P
Sbjct: 194 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI--SHWPY 251
Query: 272 LPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG--- 328
L + T + + L + LS HC+ A+ A L ++ + S +S +EG
Sbjct: 252 LDTMTPNCLYGLNLTSLSIT--HCNLTAVPYLAVRHLVYLRFLNLSYNPIST--IEGSML 307
Query: 329 HFLKKLKFPELCAGQWASMVNLSPRLPIQQLLALNVSVNR 368
H L +L+ +L GQ A + + R + L LNVS N+
Sbjct: 308 HELLRLQEIQLVGGQLAVVEPYAFR-GLNYLRVLNVSGNQ 346
Score = 78.6 bits (185), Expect = 2e-13
Identities = 50/173 (28%), Positives = 90/173 (52%), Gaps = 1/173 (0%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
+ L L +N ++ ++ + F S L ++L+ N + + F N L T+ + +NR+
Sbjct: 74 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 133
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXX 139
+P F GL +L LD+S+NKI + + F L NL+ L++ DN + IS AF
Sbjct: 134 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 193
Query: 140 XXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDL 192
++ L +IPT+ ++L LI L L + N+ ++ F+ L L+ L++
Sbjct: 194 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 246
>AY324320-1|AAQ97216.1| 620|Homo sapiens leucine-rich repeat
neuronal 6A protein.
Length = 620
Score = 93.9 bits (223), Expect = 6e-18
Identities = 90/341 (26%), Positives = 147/341 (43%), Gaps = 35/341 (10%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N V + G F +L NL+TL L+ N L+ I FT L +D+S N + L + +F
Sbjct: 104 ENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMF 163
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
+ L+++++ +N +VY+ +F GL SL+ L L K + +I S L L +L+L
Sbjct: 164 QDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLR 223
Query: 122 DNKINNISDNAFENXXXXXXXXXDR-NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
IN I D +F+ L + L L L +++ NL ++ +
Sbjct: 224 HLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLN-LTSLSITHCNLTAVPYLA 282
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXX 240
L LR L+L N +S I + + L+++ L +L + AF G
Sbjct: 283 VRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRG--------- 333
Query: 241 XXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHAL 300
L L L + GN +L + L + L NP CDC L
Sbjct: 334 ---------------LNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPLACDCRLL 378
Query: 301 YI--SAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPEL 339
++ W RLN + PTC +P +++G K FP++
Sbjct: 379 WVFRRRW-RLNFNR---QQPTCATPEFVQGKEFK--DFPDV 413
Score = 80.2 bits (189), Expect = 7e-14
Identities = 78/280 (27%), Positives = 127/280 (45%), Gaps = 11/280 (3%)
Query: 93 QILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN 151
++LDL KN+I+ + F S +L+ L+L++N ++ + AF N N+LK
Sbjct: 74 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 133
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNL 211
IP +F L L LD+S N ++ L F+ L L++L++ +N L I FS +L
Sbjct: 134 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 193
Query: 212 EKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPS 271
E+L L K L I A + +F L L L + + +P
Sbjct: 194 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI--SHWPY 251
Query: 272 LPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG--- 328
L + T + + L + LS HC+ A+ A L ++ + S +S +EG
Sbjct: 252 LDTMTPNCLYGLNLTSLSIT--HCNLTAVPYLAVRHLVYLRFLNLSYNPIST--IEGSML 307
Query: 329 HFLKKLKFPELCAGQWASMVNLSPRLPIQQLLALNVSVNR 368
H L +L+ +L GQ A + + R + L LNVS N+
Sbjct: 308 HELLRLQEIQLVGGQLAVVEPYAFR-GLNYLRVLNVSGNQ 346
Score = 78.6 bits (185), Expect = 2e-13
Identities = 50/173 (28%), Positives = 90/173 (52%), Gaps = 1/173 (0%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
+ L L +N ++ ++ + F S L ++L+ N + + F N L T+ + +NR+
Sbjct: 74 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 133
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXX 139
+P F GL +L LD+S+NKI + + F L NL+ L++ DN + IS AF
Sbjct: 134 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 193
Query: 140 XXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDL 192
++ L +IPT+ ++L LI L L + N+ ++ F+ L L+ L++
Sbjct: 194 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 246
>AL834260-1|CAD38935.1| 577|Homo sapiens hypothetical protein
protein.
Length = 577
Score = 93.9 bits (223), Expect = 6e-18
Identities = 90/341 (26%), Positives = 147/341 (43%), Gaps = 35/341 (10%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N V + G F +L NL+TL L+ N L+ I FT L +D+S N + L + +F
Sbjct: 61 ENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMF 120
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
+ L+++++ +N +VY+ +F GL SL+ L L K + +I S L L +L+L
Sbjct: 121 QDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLR 180
Query: 122 DNKINNISDNAFENXXXXXXXXXDR-NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
IN I D +F+ L + L L L +++ NL ++ +
Sbjct: 181 HLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLN-LTSLSITHCNLTAVPYLA 239
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXX 240
L LR L+L N +S I + + L+++ L +L + AF G
Sbjct: 240 VRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRG--------- 290
Query: 241 XXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHAL 300
L L L + GN +L + L + L NP CDC L
Sbjct: 291 ---------------LNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPLACDCRLL 335
Query: 301 YI--SAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPEL 339
++ W RLN + PTC +P +++G K FP++
Sbjct: 336 WVFRRRW-RLNFNR---QQPTCATPEFVQGKEFK--DFPDV 370
Score = 80.2 bits (189), Expect = 7e-14
Identities = 78/280 (27%), Positives = 127/280 (45%), Gaps = 11/280 (3%)
Query: 93 QILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN 151
++LDL KN+I+ + F S +L+ L+L++N ++ + AF N N+LK
Sbjct: 31 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 90
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNL 211
IP +F L L LD+S N ++ L F+ L L++L++ +N L I FS +L
Sbjct: 91 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 150
Query: 212 EKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPS 271
E+L L K L I A + +F L L L + + +P
Sbjct: 151 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI--SHWPY 208
Query: 272 LPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG--- 328
L + T + + L + LS HC+ A+ A L ++ + S +S +EG
Sbjct: 209 LDTMTPNCLYGLNLTSLSIT--HCNLTAVPYLAVRHLVYLRFLNLSYNPIST--IEGSML 264
Query: 329 HFLKKLKFPELCAGQWASMVNLSPRLPIQQLLALNVSVNR 368
H L +L+ +L GQ A + + R + L LNVS N+
Sbjct: 265 HELLRLQEIQLVGGQLAVVEPYAFR-GLNYLRVLNVSGNQ 303
Score = 78.6 bits (185), Expect = 2e-13
Identities = 50/173 (28%), Positives = 90/173 (52%), Gaps = 1/173 (0%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
+ L L +N ++ ++ + F S L ++L+ N + + F N L T+ + +NR+
Sbjct: 31 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 90
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXX 139
+P F GL +L LD+S+NKI + + F L NL+ L++ DN + IS AF
Sbjct: 91 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 150
Query: 140 XXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDL 192
++ L +IPT+ ++L LI L L + N+ ++ F+ L L+ L++
Sbjct: 151 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 203
>BC068558-1|AAH68558.1| 614|Homo sapiens LINGO1 protein protein.
Length = 614
Score = 93.5 bits (222), Expect = 7e-18
Identities = 90/341 (26%), Positives = 146/341 (42%), Gaps = 35/341 (10%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N V + G F +L NL+TL L+ N L+ I FT L +D+S N + L + +F
Sbjct: 98 ENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMF 157
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
+ L ++++ +N +VY+ +F GL SL+ L L K + +I S L L +L+L
Sbjct: 158 QDLYNLRSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLR 217
Query: 122 DNKINNISDNAFENXXXXXXXXXDR-NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
IN I D +F+ L + L L L +++ NL ++ +
Sbjct: 218 HLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLN-LTSLSITHCNLTAVPYLA 276
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXX 240
L LR L+L N +S I + + L+++ L +L + AF G
Sbjct: 277 VRHLVYLRFLNLSYNRISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRG--------- 327
Query: 241 XXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHAL 300
L L L + GN +L + L + L NP CDC L
Sbjct: 328 ---------------LNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPLACDCRLL 372
Query: 301 YI--SAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPEL 339
++ W RLN + PTC +P +++G K FP++
Sbjct: 373 WVFRRRW-RLNFNR---QQPTCATPEFVQGKEFK--DFPDV 407
Score = 81.4 bits (192), Expect = 3e-14
Identities = 79/280 (28%), Positives = 127/280 (45%), Gaps = 11/280 (3%)
Query: 93 QILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN 151
++LDL KN+I+ + F S +L+ L+L++N ++ + AF N N+LK
Sbjct: 68 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 127
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNL 211
IP +F L L LD+S N ++ L F+ L LR+L++ +N L I FS +L
Sbjct: 128 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLRSLEVGDNDLVYISHRAFSGLNSL 187
Query: 212 EKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPS 271
E+L L K L I A + +F L L L + + +P
Sbjct: 188 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI--SHWPY 245
Query: 272 LPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG--- 328
L + T + + L + LS HC+ A+ A L ++ + S +S +EG
Sbjct: 246 LDTMTPNCLYGLNLTSLSIT--HCNLTAVPYLAVRHLVYLRFLNLSYNRIST--IEGSML 301
Query: 329 HFLKKLKFPELCAGQWASMVNLSPRLPIQQLLALNVSVNR 368
H L +L+ +L GQ A + + R + L LNVS N+
Sbjct: 302 HELLRLQEIQLVGGQLAVVEPYAFR-GLNYLRVLNVSGNQ 340
>AY358284-1|AAQ88651.1| 620|Homo sapiens QVSK201 protein.
Length = 620
Score = 92.7 bits (220), Expect = 1e-17
Identities = 90/341 (26%), Positives = 146/341 (42%), Gaps = 35/341 (10%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N V + G F +L NL+TL L+ N L+ I FT L D+S N + L + +F
Sbjct: 104 ENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKQDISENKIVILLDYMF 163
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
+ L+++++ +N +VY+ +F GL SL+ L L K + +I S L L +L+L
Sbjct: 164 QDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLR 223
Query: 122 DNKINNISDNAFENXXXXXXXXXDR-NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
IN I D +F+ L + L L L +++ NL ++ +
Sbjct: 224 HLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLN-LTSLSITHCNLTAVPYLA 282
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXX 240
L LR L+L N +S I + + L+++ L +L + AF G
Sbjct: 283 VRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRG--------- 333
Query: 241 XXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHAL 300
L L L + GN +L + L + L NP CDC L
Sbjct: 334 ---------------LNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPLACDCRLL 378
Query: 301 YI--SAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPEL 339
++ W RLN + PTC +P +++G K FP++
Sbjct: 379 WVFRRRW-RLNFNR---QQPTCATPEFVQGKEFK--DFPDV 413
Score = 77.8 bits (183), Expect = 4e-13
Identities = 77/280 (27%), Positives = 126/280 (45%), Gaps = 11/280 (3%)
Query: 93 QILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN 151
++LDL KN+I+ + F S +L+ L+L++N ++ + AF N N+LK
Sbjct: 74 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 133
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNL 211
IP +F L L D+S N ++ L F+ L L++L++ +N L I FS +L
Sbjct: 134 IPLGVFTGLSNLTKQDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 193
Query: 212 EKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPS 271
E+L L K L I A + +F L L L + + +P
Sbjct: 194 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI--SHWPY 251
Query: 272 LPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEG--- 328
L + T + + L + LS HC+ A+ A L ++ + S +S +EG
Sbjct: 252 LDTMTPNCLYGLNLTSLSIT--HCNLTAVPYLAVRHLVYLRFLNLSYNPIST--IEGSML 307
Query: 329 HFLKKLKFPELCAGQWASMVNLSPRLPIQQLLALNVSVNR 368
H L +L+ +L GQ A + + R + L LNVS N+
Sbjct: 308 HELLRLQEIQLVGGQLAVVEPYAFR-GLNYLRVLNVSGNQ 346
Score = 76.2 bits (179), Expect = 1e-12
Identities = 49/173 (28%), Positives = 89/173 (51%), Gaps = 1/173 (0%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
+ L L +N ++ ++ + F S L ++L+ N + + F N L T+ + +NR+
Sbjct: 74 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 133
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXX 139
+P F GL +L D+S+NKI + + F L NL+ L++ DN + IS AF
Sbjct: 134 IPLGVFTGLSNLTKQDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 193
Query: 140 XXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDL 192
++ L +IPT+ ++L LI L L + N+ ++ F+ L L+ L++
Sbjct: 194 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 246
>BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2
(Drosophila) protein.
Length = 1529
Score = 92.3 bits (219), Expect = 2e-17
Identities = 65/242 (26%), Positives = 109/242 (45%), Gaps = 3/242 (1%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N + I F L+ L L L N + ++ F+ LK L L L N L P+ F
Sbjct: 65 NNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFL 124
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
L +LDLS+N+++ I AF G + AF L++L L L+
Sbjct: 125 GTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNN 184
Query: 267 NMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYL 326
N L + ++MPKL +L N +CDCH ++S W+R ++ Y+ C+ P +L
Sbjct: 185 NNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLR-QRPRVGLYT-QCMGPSHL 242
Query: 327 EGHFLKKLKFPE-LCAGQWASMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWPIPVSESI 385
GH + +++ E +C+G + M L + ++ C+ G+ P + E+I
Sbjct: 243 RGHNVAEVQKREFVCSGHQSFMAPSCSVLHCPAACTCSNNIVDCRGKGLTEIPTNLPETI 302
Query: 386 LD 387
+
Sbjct: 303 TE 304
Score = 77.0 bits (181), Expect = 7e-13
Identities = 41/133 (30%), Positives = 74/133 (55%), Gaps = 1/133 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ + F L +L+ L+L N + I+ AF K+L + L+ N+L PE LF
Sbjct: 65 NNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFL 124
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+S N++ +P +F G ++ L L N+I I++G F +L++L++L L++
Sbjct: 125 GTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNN 184
Query: 123 NKINNISDNAFEN 135
N I +S +F +
Sbjct: 185 NNITRLSVASFNH 197
Score = 74.1 bits (174), Expect = 5e-12
Identities = 41/112 (36%), Positives = 63/112 (56%), Gaps = 1/112 (0%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
+RL++N ++ I AF+ KKL +DLSNN + L F L ++ + N++ +P
Sbjct: 305 IRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELP 364
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAF 133
F GL+SLQ+L L+ NKI ++ F L NL +L L DNK+ I+ F
Sbjct: 365 KSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTF 416
Score = 72.5 bits (170), Expect = 1e-11
Identities = 44/136 (32%), Positives = 70/136 (51%), Gaps = 1/136 (0%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
LDL+ N I I F+ L++L++L+L +NKI+ I AF++ +RN L+ P
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
LF L LDLS N + ++ F ++NL L N +S I D F +LE
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 214 LDLSKNKLRFINITAF 229
L L+ N + +++ +F
Sbjct: 180 LTLNNNNITRLSVASF 195
Score = 70.9 bits (166), Expect = 4e-11
Identities = 34/126 (26%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N + + G F+ L L+ LRL RN+L+ F T KL+ +DLS N + +P K
Sbjct: 86 LMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRK 145
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
F ++ + + N++ + +F L L++L L+ N I + +F+ + L+ +
Sbjct: 146 AFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFR 205
Query: 120 LSDNKI 125
L N +
Sbjct: 206 LHSNNL 211
Score = 70.9 bits (166), Expect = 4e-11
Identities = 86/433 (19%), Positives = 174/433 (40%), Gaps = 31/433 (7%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
++ N + LP +FE L +L+ L L N + + +AF L + L +N L T+ +
Sbjct: 355 LYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKG 414
Query: 61 LFANNTFLETIDISNNRVV----------YVPSDSF--LGLYSLQILDLSKNKIQNIQNG 108
F+ ++T+ ++ N + Y+ ++ G L+ +I I++
Sbjct: 415 TFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPIETSGARCTSPRRLANKRIGQIKSK 474
Query: 109 TF--SLKNLQILKLSDNKINNISDNAFENXX-------XXXXXXXDRNKLKNIPTQLFNN 159
F S K + +++ + +S + F + KL IP +
Sbjct: 475 KFRCSAKEQYFIPGTEDYRSKLSGDCFADLACPEKCRCEGTTVDCSNQKLNKIPEHI--- 531
Query: 160 LKCLIFLDLSNNNLMSLAGVE-FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSK 218
+ L L+NN L F+ L LR ++ N ++ I + F + ++ L+
Sbjct: 532 PQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTS 591
Query: 219 NKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLD 278
N+L + F G V +F L ++ L L N ++ D
Sbjct: 592 NRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFD 651
Query: 279 YMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPE 338
+ L+ + L NP++C+C+ ++ W+R + +I +P C P++L+ ++ + +
Sbjct: 652 TLHSLSTLNLLANPFNCNCYLAWLGEWLR--KKRIVTGNPRCQKPYFLKEIPIQDVAIQD 709
Query: 339 LCAGQWASMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWP--IP--VSESILDTHTGYVL 394
+ SP +V RC G+ + P IP V+E LD + ++
Sbjct: 710 FTCDDGNDDNSCSPLSRCPTECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLV 769
Query: 395 DRGTTDIEDITTI 407
+ ++ + +T I
Sbjct: 770 PKELSNYKHLTLI 782
Score = 67.7 bits (158), Expect = 4e-10
Identities = 37/121 (30%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ +P G F L+ + L N + E+ +AF + L + L N + LP+ LF
Sbjct: 310 NTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFE 369
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L+ + ++ N++ + D+F L++L +L L NK+Q I GTFS L+ +Q + L+
Sbjct: 370 GLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQ 429
Query: 123 N 123
N
Sbjct: 430 N 430
Score = 65.7 bits (153), Expect = 2e-09
Identities = 50/191 (26%), Positives = 87/191 (45%), Gaps = 26/191 (13%)
Query: 145 DRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNT 204
++N +K IP F+ K L +DLSNN + LA F+ L+ L +L L N ++++P +
Sbjct: 308 EQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSL 367
Query: 205 FSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYL 264
F F+L+ L L+ NK+ + + AF L NL L L
Sbjct: 368 FEGLFSLQLLLLNANKINCLRVDAFQD------------------------LHNLNLLSL 403
Query: 265 DGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPW 324
N ++ T + + + L+ NP+ CDCH +++ ++ N ++ C SP
Sbjct: 404 YDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPIE--TSGARCTSPR 461
Query: 325 YLEGHFLKKLK 335
L + ++K
Sbjct: 462 RLANKRIGQIK 472
Score = 61.3 bits (142), Expect = 4e-08
Identities = 44/156 (28%), Positives = 69/156 (44%), Gaps = 1/156 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L N + I F + L + L N + T+ F + LE + ++ N +
Sbjct: 56 NTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHL 115
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXX 137
P FLG L LDLS+N+IQ I F +++ L+L N+I+ I D AF
Sbjct: 116 QLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALR 175
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ N + + FN++ L L +NNL
Sbjct: 176 DLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 58.8 bits (136), Expect = 2e-07
Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 1/152 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+DL+ N + + + FA L + + N++ + +F L L+ L L++N +Q
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 107 NGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
F L L LS+N+I I AF D N++ I F L+ L
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
L L+NNN+ L+ F + LR L N L
Sbjct: 180 LTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 58.4 bits (135), Expect = 3e-07
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 1/124 (0%)
Query: 97 LSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQ 155
L +N I+ I G FS K L+ + LS+N+I+ ++ +AF+ NK+ +P
Sbjct: 307 LEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKS 366
Query: 156 LFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLD 215
LF L L L L+ N + L F+ L L L L +N L I TFS ++ +
Sbjct: 367 LFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMH 426
Query: 216 LSKN 219
L++N
Sbjct: 427 LAQN 430
Score = 54.8 bits (126), Expect = 3e-06
Identities = 41/121 (33%), Positives = 62/121 (51%), Gaps = 5/121 (4%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
++ LP GI + L L N + E ++ K L +DLSNN + TL + F+N
Sbjct: 745 LKVLPKGIPRDVTELY---LDGNQFTLVPKE-LSNYKHLTLIDLSNNRISTLSNQSFSNM 800
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNK 124
T L T+ +S NR+ +P +F GL SL++L L N I + G F+ L L L + N
Sbjct: 801 TQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANP 860
Query: 125 I 125
+
Sbjct: 861 L 861
Score = 53.6 bits (123), Expect = 7e-06
Identities = 67/318 (21%), Positives = 126/318 (39%), Gaps = 22/318 (6%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + + G FE + + L N LE + + F + L + L +N + + F
Sbjct: 567 NNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSF 626
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI----------QNIQNGTFSL 112
+ + + + +N++ V +F L+SL L+L N + ++
Sbjct: 627 IGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRIVT 686
Query: 113 KNLQILKLSDNKINNISDNAFENXXXXXXXXXDR-NKLKNIPTQLFNNLKCL-IFLDLSN 170
N + K K I D A ++ + + L PT+ CL + SN
Sbjct: 687 GNPRCQKPYFLKEIPIQDVAIQDFTCDDGNDDNSCSPLSRCPTEC----TCLDTVVRCSN 742
Query: 171 NNLMSLA-GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
L L G+ + +L L N + +P S+ +L +DLS N++ ++ +F
Sbjct: 743 KGLKVLPKGIPRDVTELY----LDGNQFTLVPKE-LSNYKHLTLIDLSNNRISTLSNQSF 797
Query: 230 YGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLS 289
+ + F LK+L L L GN +P + + L+ + +
Sbjct: 798 SNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIG 857
Query: 290 GNPWHCDCHALYISAWVR 307
NP +CDC+ ++S WV+
Sbjct: 858 ANPLYCDCNMQWLSDWVK 875
Score = 43.6 bits (98), Expect = 0.008
Identities = 31/107 (28%), Positives = 44/107 (41%)
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
++L N I I AF N++ + F L+ L L L N + L
Sbjct: 305 IRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELP 364
Query: 178 GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
FE L L+ L L N ++ + + F D NL L L NKL+ I
Sbjct: 365 KSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTI 411
>AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellular
slit protein Slit2 protein.
Length = 1521
Score = 92.3 bits (219), Expect = 2e-17
Identities = 65/242 (26%), Positives = 109/242 (45%), Gaps = 3/242 (1%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N + I F L+ L L L N + ++ F+ LK L L L N L P+ F
Sbjct: 65 NNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFL 124
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
L +LDLS+N+++ I AF G + AF L++L L L+
Sbjct: 125 GTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNN 184
Query: 267 NMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYL 326
N L + ++MPKL +L N +CDCH ++S W+R ++ Y+ C+ P +L
Sbjct: 185 NNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLR-QRPRVGLYT-QCMGPSHL 242
Query: 327 EGHFLKKLKFPE-LCAGQWASMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWPIPVSESI 385
GH + +++ E +C+G + M L + ++ C+ G+ P + E+I
Sbjct: 243 RGHNVAEVQKREFVCSGHQSFMAPSCSVLHCPAACTCSNNIVDCRGKGLTEIPTNLPETI 302
Query: 386 LD 387
+
Sbjct: 303 TE 304
Score = 77.0 bits (181), Expect = 7e-13
Identities = 41/133 (30%), Positives = 74/133 (55%), Gaps = 1/133 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ + F L +L+ L+L N + I+ AF K+L + L+ N+L PE LF
Sbjct: 65 NNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFL 124
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+S N++ +P +F G ++ L L N+I I++G F +L++L++L L++
Sbjct: 125 GTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNN 184
Query: 123 NKINNISDNAFEN 135
N I +S +F +
Sbjct: 185 NNITRLSVASFNH 197
Score = 74.1 bits (174), Expect = 5e-12
Identities = 41/112 (36%), Positives = 63/112 (56%), Gaps = 1/112 (0%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
+RL++N ++ I AF+ KKL +DLSNN + L F L ++ + N++ +P
Sbjct: 305 IRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELP 364
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAF 133
F GL+SLQ+L L+ NKI ++ F L NL +L L DNK+ I+ F
Sbjct: 365 KSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTF 416
Score = 72.5 bits (170), Expect = 1e-11
Identities = 44/136 (32%), Positives = 70/136 (51%), Gaps = 1/136 (0%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
LDL+ N I I F+ L++L++L+L +NKI+ I AF++ +RN L+ P
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
LF L LDLS N + ++ F ++NL L N +S I D F +LE
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 214 LDLSKNKLRFINITAF 229
L L+ N + +++ +F
Sbjct: 180 LTLNNNNITRLSVASF 195
Score = 71.3 bits (167), Expect = 3e-11
Identities = 85/426 (19%), Positives = 169/426 (39%), Gaps = 25/426 (5%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
++ N + LP +FE L +L+ L L N + + +AF L + L +N L T+ +
Sbjct: 355 LYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKG 414
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLY-------SLQILDLSKNKIQNIQNGTFSLK 113
F+ ++T+ ++ N + +L Y + S ++ N + G K
Sbjct: 415 TFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPIETSGARCTSPRRLANKRIGQIKSK 474
Query: 114 NLQILKLSDNKINNISDNAFENXX-------XXXXXXXDRNKLKNIPTQLFNNLKCLIFL 166
+ D + + +S + F + KL IP + + L
Sbjct: 475 KFRCSGTEDYR-SKLSGDCFADLACPEKCRCEGTTVDCSNQKLNKIPEHI---PQYTAEL 530
Query: 167 DLSNNNLMSLAGVE-FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
L+NN L F+ L LR ++ N ++ I + F + ++ L+ N+L +
Sbjct: 531 RLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQ 590
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
F G V +F L ++ L L N ++ D + L+
Sbjct: 591 HKMFKGLEKPQNLMLRSNRITCVGNDSFIGLSSVRMLSLYDNQITTVAPGAFDTLHSLST 650
Query: 286 VKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPELCAGQWA 345
+ L NP++C+C+ ++ W+R + +I +P C P++L+ ++ + +
Sbjct: 651 LNLLANPFNCNCYLAWLGEWLR--KKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCDDGN 708
Query: 346 SMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWP--IP--VSESILDTHTGYVLDRGTTDI 401
+ SP +V RC G+ + P IP V+E LD + ++ + ++
Sbjct: 709 DDNSCSPLSRCPTECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPKELSNY 768
Query: 402 EDITTI 407
+ +T I
Sbjct: 769 KHLTLI 774
Score = 70.9 bits (166), Expect = 4e-11
Identities = 34/126 (26%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N + + G F+ L L+ LRL RN+L+ F T KL+ +DLS N + +P K
Sbjct: 86 LMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRK 145
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
F ++ + + N++ + +F L L++L L+ N I + +F+ + L+ +
Sbjct: 146 AFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFR 205
Query: 120 LSDNKI 125
L N +
Sbjct: 206 LHSNNL 211
Score = 67.7 bits (158), Expect = 4e-10
Identities = 37/121 (30%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ +P G F L+ + L N + E+ +AF + L + L N + LP+ LF
Sbjct: 310 NTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFE 369
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L+ + ++ N++ + D+F L++L +L L NK+Q I GTFS L+ +Q + L+
Sbjct: 370 GLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQ 429
Query: 123 N 123
N
Sbjct: 430 N 430
Score = 66.9 bits (156), Expect = 7e-10
Identities = 52/199 (26%), Positives = 91/199 (45%), Gaps = 27/199 (13%)
Query: 145 DRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNT 204
++N +K IP F+ K L +DLSNN + LA F+ L+ L +L L N ++++P +
Sbjct: 308 EQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSL 367
Query: 205 FSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYL 264
F F+L+ L L+ NK+ + + AF L NL L L
Sbjct: 368 FEGLFSLQLLLLNANKINCLRVDAFQD------------------------LHNLNLLSL 403
Query: 265 DGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPW 324
N ++ T + + + L+ NP+ CDCH +++ ++ N ++ C SP
Sbjct: 404 YDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPIE--TSGARCTSPR 461
Query: 325 YLEGHFLKKLKFPEL-CAG 342
L + ++K + C+G
Sbjct: 462 RLANKRIGQIKSKKFRCSG 480
Score = 61.3 bits (142), Expect = 4e-08
Identities = 44/156 (28%), Positives = 69/156 (44%), Gaps = 1/156 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L N + I F + L + L N + T+ F + LE + ++ N +
Sbjct: 56 NTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHL 115
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXX 137
P FLG L LDLS+N+IQ I F +++ L+L N+I+ I D AF
Sbjct: 116 QLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALR 175
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ N + + FN++ L L +NNL
Sbjct: 176 DLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 58.8 bits (136), Expect = 2e-07
Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 1/152 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+DL+ N + + + FA L + + N++ + +F L L+ L L++N +Q
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 107 NGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
F L L LS+N+I I AF D N++ I F L+ L
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
L L+NNN+ L+ F + LR L N L
Sbjct: 180 LTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 58.4 bits (135), Expect = 3e-07
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 1/124 (0%)
Query: 97 LSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQ 155
L +N I+ I G FS K L+ + LS+N+I+ ++ +AF+ NK+ +P
Sbjct: 307 LEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKS 366
Query: 156 LFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLD 215
LF L L L L+ N + L F+ L L L L +N L I TFS ++ +
Sbjct: 367 LFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMH 426
Query: 216 LSKN 219
L++N
Sbjct: 427 LAQN 430
Score = 54.8 bits (126), Expect = 3e-06
Identities = 41/121 (33%), Positives = 62/121 (51%), Gaps = 5/121 (4%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
++ LP GI + L L N + E ++ K L +DLSNN + TL + F+N
Sbjct: 737 LKVLPKGIPRDVTELY---LDGNQFTLVPKE-LSNYKHLTLIDLSNNRISTLSNQSFSNM 792
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNK 124
T L T+ +S NR+ +P +F GL SL++L L N I + G F+ L L L + N
Sbjct: 793 TQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANP 852
Query: 125 I 125
+
Sbjct: 853 L 853
Score = 54.0 bits (124), Expect = 6e-06
Identities = 67/318 (21%), Positives = 127/318 (39%), Gaps = 22/318 (6%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + + G FE + + L N LE + + F +K ++ L +N + + F
Sbjct: 559 NNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLEKPQNLMLRSNRITCVGNDSF 618
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI----------QNIQNGTFSL 112
+ + + + +N++ V +F L+SL L+L N + ++
Sbjct: 619 IGLSSVRMLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRIVT 678
Query: 113 KNLQILKLSDNKINNISDNAFENXXXXXXXXXDR-NKLKNIPTQLFNNLKCL-IFLDLSN 170
N + K K I D A ++ + + L PT+ CL + SN
Sbjct: 679 GNPRCQKPYFLKEIPIQDVAIQDFTCDDGNDDNSCSPLSRCPTEC----TCLDTVVRCSN 734
Query: 171 NNLMSLA-GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
L L G+ + +L L N + +P S+ +L +DLS N++ ++ +F
Sbjct: 735 KGLKVLPKGIPRDVTELY----LDGNQFTLVPKE-LSNYKHLTLIDLSNNRISTLSNQSF 789
Query: 230 YGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLS 289
+ + F LK+L L L GN +P + + L+ + +
Sbjct: 790 SNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIG 849
Query: 290 GNPWHCDCHALYISAWVR 307
NP +CDC+ ++S WV+
Sbjct: 850 ANPLYCDCNMQWLSDWVK 867
Score = 43.6 bits (98), Expect = 0.008
Identities = 31/107 (28%), Positives = 44/107 (41%)
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
++L N I I AF N++ + F L+ L L L N + L
Sbjct: 305 IRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELP 364
Query: 178 GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
FE L L+ L L N ++ + + F D NL L L NKL+ I
Sbjct: 365 KSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTI 411
>AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein.
Length = 1529
Score = 92.3 bits (219), Expect = 2e-17
Identities = 65/242 (26%), Positives = 109/242 (45%), Gaps = 3/242 (1%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N + I F L+ L L L N + ++ F+ LK L L L N L P+ F
Sbjct: 65 NNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFL 124
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
L +LDLS+N+++ I AF G + AF L++L L L+
Sbjct: 125 GTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNN 184
Query: 267 NMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYL 326
N L + ++MPKL +L N +CDCH ++S W+R ++ Y+ C+ P +L
Sbjct: 185 NNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLR-QRPRVGLYT-QCMGPSHL 242
Query: 327 EGHFLKKLKFPE-LCAGQWASMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWPIPVSESI 385
GH + +++ E +C+G + M L + ++ C+ G+ P + E+I
Sbjct: 243 RGHNVAEVQKREFVCSGHQSFMAPSCSVLHCPAACTCSNNIVDCRGKGLTEIPTNLPETI 302
Query: 386 LD 387
+
Sbjct: 303 TE 304
Score = 77.0 bits (181), Expect = 7e-13
Identities = 41/133 (30%), Positives = 74/133 (55%), Gaps = 1/133 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ + F L +L+ L+L N + I+ AF K+L + L+ N+L PE LF
Sbjct: 65 NNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFL 124
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+S N++ +P +F G ++ L L N+I I++G F +L++L++L L++
Sbjct: 125 GTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNN 184
Query: 123 NKINNISDNAFEN 135
N I +S +F +
Sbjct: 185 NNITRLSVASFNH 197
Score = 74.1 bits (174), Expect = 5e-12
Identities = 41/112 (36%), Positives = 63/112 (56%), Gaps = 1/112 (0%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
+RL++N ++ I AF+ KKL +DLSNN + L F L ++ + N++ +P
Sbjct: 305 IRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELP 364
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAF 133
F GL+SLQ+L L+ NKI ++ F L NL +L L DNK+ I+ F
Sbjct: 365 KSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTF 416
Score = 72.5 bits (170), Expect = 1e-11
Identities = 44/136 (32%), Positives = 70/136 (51%), Gaps = 1/136 (0%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
LDL+ N I I F+ L++L++L+L +NKI+ I AF++ +RN L+ P
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
LF L LDLS N + ++ F ++NL L N +S I D F +LE
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 214 LDLSKNKLRFINITAF 229
L L+ N + +++ +F
Sbjct: 180 LTLNNNNITRLSVASF 195
Score = 70.9 bits (166), Expect = 4e-11
Identities = 34/126 (26%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N + + G F+ L L+ LRL RN+L+ F T KL+ +DLS N + +P K
Sbjct: 86 LMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRK 145
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
F ++ + + N++ + +F L L++L L+ N I + +F+ + L+ +
Sbjct: 146 AFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFR 205
Query: 120 LSDNKI 125
L N +
Sbjct: 206 LHSNNL 211
Score = 70.9 bits (166), Expect = 4e-11
Identities = 86/433 (19%), Positives = 174/433 (40%), Gaps = 31/433 (7%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
++ N + LP +FE L +L+ L L N + + +AF L + L +N L T+ +
Sbjct: 355 LYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKG 414
Query: 61 LFANNTFLETIDISNNRVV----------YVPSDSF--LGLYSLQILDLSKNKIQNIQNG 108
F+ ++T+ ++ N + Y+ ++ G L+ +I I++
Sbjct: 415 TFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPIETSGARCTSPRRLANKRIGQIKSK 474
Query: 109 TF--SLKNLQILKLSDNKINNISDNAFENXX-------XXXXXXXDRNKLKNIPTQLFNN 159
F S K + +++ + +S + F + KL IP +
Sbjct: 475 KFRCSAKEQYFIPGTEDYRSKLSGDCFADLACPEKCRCEGTTVDCSNQKLNKIPEHI--- 531
Query: 160 LKCLIFLDLSNNNLMSLAGVE-FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSK 218
+ L L+NN L F+ L LR ++ N ++ I + F + ++ L+
Sbjct: 532 PQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTS 591
Query: 219 NKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLD 278
N+L + F G V +F L ++ L L N ++ D
Sbjct: 592 NRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFD 651
Query: 279 YMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPE 338
+ L+ + L NP++C+C+ ++ W+R + +I +P C P++L+ ++ + +
Sbjct: 652 TLHSLSTLNLLANPFNCNCYLAWLGEWLR--KKRIVTGNPRCQKPYFLKEIPIQDVAIQD 709
Query: 339 LCAGQWASMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWP--IP--VSESILDTHTGYVL 394
+ SP +V RC G+ + P IP V+E LD + ++
Sbjct: 710 FTCDDGNDDNSCSPLSRCPTECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLV 769
Query: 395 DRGTTDIEDITTI 407
+ ++ + +T I
Sbjct: 770 PKELSNYKHLTLI 782
Score = 67.7 bits (158), Expect = 4e-10
Identities = 37/121 (30%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ +P G F L+ + L N + E+ +AF + L + L N + LP+ LF
Sbjct: 310 NTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFE 369
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L+ + ++ N++ + D+F L++L +L L NK+Q I GTFS L+ +Q + L+
Sbjct: 370 GLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQ 429
Query: 123 N 123
N
Sbjct: 430 N 430
Score = 65.7 bits (153), Expect = 2e-09
Identities = 50/191 (26%), Positives = 87/191 (45%), Gaps = 26/191 (13%)
Query: 145 DRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNT 204
++N +K IP F+ K L +DLSNN + LA F+ L+ L +L L N ++++P +
Sbjct: 308 EQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSL 367
Query: 205 FSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYL 264
F F+L+ L L+ NK+ + + AF L NL L L
Sbjct: 368 FEGLFSLQLLLLNANKINCLRVDAFQD------------------------LHNLNLLSL 403
Query: 265 DGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPW 324
N ++ T + + + L+ NP+ CDCH +++ ++ N ++ C SP
Sbjct: 404 YDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPIE--TSGARCTSPR 461
Query: 325 YLEGHFLKKLK 335
L + ++K
Sbjct: 462 RLANKRIGQIK 472
Score = 61.3 bits (142), Expect = 4e-08
Identities = 44/156 (28%), Positives = 69/156 (44%), Gaps = 1/156 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L N + I F + L + L N + T+ F + LE + ++ N +
Sbjct: 56 NTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHL 115
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXX 137
P FLG L LDLS+N+IQ I F +++ L+L N+I+ I D AF
Sbjct: 116 QLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALR 175
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ N + + FN++ L L +NNL
Sbjct: 176 DLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 58.8 bits (136), Expect = 2e-07
Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 1/152 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+DL+ N + + + FA L + + N++ + +F L L+ L L++N +Q
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 107 NGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
F L L LS+N+I I AF D N++ I F L+ L
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
L L+NNN+ L+ F + LR L N L
Sbjct: 180 LTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 58.4 bits (135), Expect = 3e-07
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 1/124 (0%)
Query: 97 LSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQ 155
L +N I+ I G FS K L+ + LS+N+I+ ++ +AF+ NK+ +P
Sbjct: 307 LEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKS 366
Query: 156 LFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLD 215
LF L L L L+ N + L F+ L L L L +N L I TFS ++ +
Sbjct: 367 LFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMH 426
Query: 216 LSKN 219
L++N
Sbjct: 427 LAQN 430
Score = 54.8 bits (126), Expect = 3e-06
Identities = 41/121 (33%), Positives = 62/121 (51%), Gaps = 5/121 (4%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
++ LP GI + L L N + E ++ K L +DLSNN + TL + F+N
Sbjct: 745 LKVLPKGIPRDVTELY---LDGNQFTLVPKE-LSNYKHLTLIDLSNNRISTLSNQSFSNM 800
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNK 124
T L T+ +S NR+ +P +F GL SL++L L N I + G F+ L L L + N
Sbjct: 801 TQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANP 860
Query: 125 I 125
+
Sbjct: 861 L 861
Score = 53.6 bits (123), Expect = 7e-06
Identities = 67/318 (21%), Positives = 126/318 (39%), Gaps = 22/318 (6%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + + G FE + + L N LE + + F + L + L +N + + F
Sbjct: 567 NNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSF 626
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI----------QNIQNGTFSL 112
+ + + + +N++ V +F L+SL L+L N + ++
Sbjct: 627 IGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRIVT 686
Query: 113 KNLQILKLSDNKINNISDNAFENXXXXXXXXXDR-NKLKNIPTQLFNNLKCL-IFLDLSN 170
N + K K I D A ++ + + L PT+ CL + SN
Sbjct: 687 GNPRCQKPYFLKEIPIQDVAIQDFTCDDGNDDNSCSPLSRCPTEC----TCLDTVVRCSN 742
Query: 171 NNLMSLA-GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
L L G+ + +L L N + +P S+ +L +DLS N++ ++ +F
Sbjct: 743 KGLKVLPKGIPRDVTELY----LDGNQFTLVPKE-LSNYKHLTLIDLSNNRISTLSNQSF 797
Query: 230 YGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLS 289
+ + F LK+L L L GN +P + + L+ + +
Sbjct: 798 SNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIG 857
Query: 290 GNPWHCDCHALYISAWVR 307
NP +CDC+ ++S WV+
Sbjct: 858 ANPLYCDCNMQWLSDWVK 875
Score = 43.6 bits (98), Expect = 0.008
Identities = 31/107 (28%), Positives = 44/107 (41%)
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
++L N I I AF N++ + F L+ L L L N + L
Sbjct: 305 IRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELP 364
Query: 178 GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
FE L L+ L L N ++ + + F D NL L L NKL+ I
Sbjct: 365 KSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTI 411
>BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein.
Length = 673
Score = 91.9 bits (218), Expect = 2e-17
Identities = 78/308 (25%), Positives = 135/308 (43%), Gaps = 7/308 (2%)
Query: 62 FANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKL 120
FA L+ +D+S N++ +PS F L +L LDL+ N++ I N TF L+ L+ L L
Sbjct: 72 FAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYL 131
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
N+I +I AF+ N+L+ +P L L+ LDLS+N+L++L
Sbjct: 132 GKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPL---RLPRLLLLDLSHNSLLALEPGI 188
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXX 240
++ + L L L Q+ + FS NL LD+S N+L +
Sbjct: 189 LDTANV-EALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLA 247
Query: 241 XXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHAL 300
++ + + L L L + +LP P+L ++ + NP++C C
Sbjct: 248 GNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAARNPFNCVCPLS 307
Query: 301 YISAWVRLNEMKIWDYSPT-CVSPWYLEGHFLKKLKFPEL-CAGQWASMVNLSPRLPIQQ 358
+ WVR + + + T C P G L +L + + C + + R +++
Sbjct: 308 WFGPWVRESHVTLASPEETRCHFPPKNAGRLLLELDYADFGCPATTTTATVPTTRPVVRE 367
Query: 359 LLALNVSV 366
AL+ S+
Sbjct: 368 PTALSSSL 375
Score = 65.3 bits (152), Expect = 2e-09
Identities = 56/223 (25%), Positives = 99/223 (44%), Gaps = 5/223 (2%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+F+N + L G F L L+ L L +N + + S F L ++DL+ N L+ + +
Sbjct: 59 VFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNE 118
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKL 120
F LE + + NR+ ++ +F L L L L N+++ + L L +L L
Sbjct: 119 TFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALP--PLRLPRLLLLDL 176
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
S N + + + L+ + LF+ L+ L LD+S+N L + V
Sbjct: 177 SHNSLLALEPGILDTANVEALRLAGLG-LQQLDEGLFSRLRNLHDLDVSDNQLERVPPV- 234
Query: 181 FESLKLLRNLDLKENA-LSQIPDNTFSDCFNLEKLDLSKNKLR 222
L+ L L L N ++Q+ + L++LD+S L+
Sbjct: 235 IRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQ 277
Score = 50.0 bits (114), Expect = 9e-05
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 3/121 (2%)
Query: 171 NNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFY 230
N + L F L L+ LDL +N ++ +P F NL LDL+ N+L I F
Sbjct: 62 NGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFR 121
Query: 231 GXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSG 290
G + AF L L L L N +LP L P+L ++ LS
Sbjct: 122 GLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRL---PRLLLLDLSH 178
Query: 291 N 291
N
Sbjct: 179 N 179
Score = 37.5 bits (83), Expect = 0.51
Identities = 23/98 (23%), Positives = 41/98 (41%)
Query: 194 ENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAF 253
EN ++ + +F+ L+ LDLS+N++ + F +E+ + F
Sbjct: 61 ENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETF 120
Query: 254 SMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L+ L LYL N + D + +L +KL N
Sbjct: 121 RGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDN 158
>BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product
protein.
Length = 811
Score = 91.9 bits (218), Expect = 2e-17
Identities = 69/219 (31%), Positives = 101/219 (46%), Gaps = 3/219 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L G FE L +L LRL N L + F L ++ L +N + L + FA
Sbjct: 141 NEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFA 200
Query: 64 NNTFLETIDISNNRVV--YVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKL 120
L +++S N + + +F L SL L LS N +Q++ F L L +L L
Sbjct: 201 QLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSL 260
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
N++ +++ AF + N+L +PT L L L LDLS N L +L
Sbjct: 261 RGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPAT 320
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
F L LR L L+ NALS + + F+ L +LDL N
Sbjct: 321 FGHLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGN 359
Score = 89.4 bits (212), Expect = 1e-16
Identities = 88/337 (26%), Positives = 126/337 (37%), Gaps = 5/337 (1%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F L L+ L LQ N + + + F +L + L NN L L A L +
Sbjct: 79 FHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYA 138
Query: 74 SNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNA 132
+ N + + SF GL SL L L N + + + F+ L NL L L N+I + NA
Sbjct: 139 NGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNA 198
Query: 133 FENXXXXXXXXXDRNKLKNI--PTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNL 190
F N+L+ F L+ L L LS N+L L F+ L L L
Sbjct: 199 FAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLL 258
Query: 191 DLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHF 250
L+ N L+ + F L +L L N+L + +H
Sbjct: 259 SLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHP 318
Query: 251 KAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVR--L 308
F L L L L N +L P L + L GN W CDC + W+
Sbjct: 319 ATFGHLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGNGWTCDCRLRGLKRWMGDWH 378
Query: 309 NEMKIWDYSPTCVSPWYLEGHFLKKLKFPELCAGQWA 345
++ ++ C P L G +L L +L G A
Sbjct: 379 SQGRLLTVFVQCRHPPALRGKYLDYLDDQQLQNGSCA 415
Score = 81.0 bits (191), Expect = 4e-14
Identities = 62/222 (27%), Positives = 104/222 (46%), Gaps = 3/222 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ L G L L+ L N + + +F + L + L N L LP+ +F
Sbjct: 116 NNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVF 175
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQ-NIQNG-TFS-LKNLQILK 119
A L + + +NR+ ++ ++F L L+ L+LS N++Q ++++ TF+ L++L L
Sbjct: 176 APLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLI 235
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
LS N + ++ F++ N+L ++ + F L+ L L L N L L
Sbjct: 236 LSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTA 295
Query: 180 EFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
E L L LDL N LS + TF L +L L N L
Sbjct: 296 LLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNAL 337
Score = 78.6 bits (185), Expect = 2e-13
Identities = 70/273 (25%), Positives = 114/273 (41%), Gaps = 3/273 (1%)
Query: 22 TLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYV 81
T L N++ I + F +L +DL N + +L K F + LE + + NN + +
Sbjct: 63 TYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQAL 122
Query: 82 PSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXX 140
+ L L+IL + N+I + G+F L++L L+L N + + D F
Sbjct: 123 APGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLL 182
Query: 141 XXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLM-SLA-GVEFESLKLLRNLDLKENALS 198
+ N+++ + F L L FL+LS N L SL F L+ L +L L N+L
Sbjct: 183 YLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQ 242
Query: 199 QIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKN 258
+ F L L L N+L + AF+G ++ L +
Sbjct: 243 HLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHS 302
Query: 259 LTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L L L GN +L T ++ +L + L N
Sbjct: 303 LEALDLSGNELSALHPATFGHLGRLRELSLRNN 335
Score = 72.9 bits (171), Expect = 1e-11
Identities = 62/222 (27%), Positives = 92/222 (41%), Gaps = 4/222 (1%)
Query: 74 SNNRVVYVPSDSFL-GLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDN 131
+N + VP S L + + L N I NI F L L+ L L N+I ++
Sbjct: 42 TNRGLRVVPKTSSLPSPHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPK 101
Query: 132 AFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLD 191
FE N L+ + L+ L L + N + L+ FE L+ L L
Sbjct: 102 TFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLR 161
Query: 192 LKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF--YGXXXXXXXXXXXXXXYEVH 249
L NAL +PD F+ NL L L N++RF+ AF G H
Sbjct: 162 LDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRH 221
Query: 250 FKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
F+ L++L++L L N L R ++P+L ++ L GN
Sbjct: 222 AATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGN 263
>AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein.
Length = 673
Score = 91.9 bits (218), Expect = 2e-17
Identities = 78/308 (25%), Positives = 135/308 (43%), Gaps = 7/308 (2%)
Query: 62 FANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKL 120
FA L+ +D+S N++ +PS F L +L LDL+ N++ I N TF L+ L+ L L
Sbjct: 72 FAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYL 131
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
N+I +I AF+ N+L+ +P L L+ LDLS+N+L++L
Sbjct: 132 GKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPL---RLPRLLLLDLSHNSLLALEPGI 188
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXX 240
++ + L L L Q+ + FS NL LD+S N+L +
Sbjct: 189 LDTANV-EALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLA 247
Query: 241 XXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHAL 300
++ + + L L L + +LP P+L ++ + NP++C C
Sbjct: 248 GNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAARNPFNCVCPLS 307
Query: 301 YISAWVRLNEMKIWDYSPT-CVSPWYLEGHFLKKLKFPEL-CAGQWASMVNLSPRLPIQQ 358
+ WVR + + + T C P G L +L + + C + + R +++
Sbjct: 308 WFGPWVRESHVTLASPEETRCHFPPKNAGRLLLELDYADFGCPATTTTATVPTTRPVVRE 367
Query: 359 LLALNVSV 366
AL+ S+
Sbjct: 368 PTALSSSL 375
Score = 65.3 bits (152), Expect = 2e-09
Identities = 56/223 (25%), Positives = 99/223 (44%), Gaps = 5/223 (2%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+F+N + L G F L L+ L L +N + + S F L ++DL+ N L+ + +
Sbjct: 59 VFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNE 118
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKL 120
F LE + + NR+ ++ +F L L L L N+++ + L L +L L
Sbjct: 119 TFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALP--PLRLPRLLLLDL 176
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
S N + + + L+ + LF+ L+ L LD+S+N L + V
Sbjct: 177 SHNSLLALEPGILDTANVEALRLAGLG-LQQLDEGLFSRLRNLHDLDVSDNQLERVPPV- 234
Query: 181 FESLKLLRNLDLKENA-LSQIPDNTFSDCFNLEKLDLSKNKLR 222
L+ L L L N ++Q+ + L++LD+S L+
Sbjct: 235 IRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQ 277
Score = 50.0 bits (114), Expect = 9e-05
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 3/121 (2%)
Query: 171 NNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFY 230
N + L F L L+ LDL +N ++ +P F NL LDL+ N+L I F
Sbjct: 62 NGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFR 121
Query: 231 GXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSG 290
G + AF L L L L N +LP L P+L ++ LS
Sbjct: 122 GLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRL---PRLLLLDLSH 178
Query: 291 N 291
N
Sbjct: 179 N 179
Score = 37.5 bits (83), Expect = 0.51
Identities = 23/98 (23%), Positives = 41/98 (41%)
Query: 194 ENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAF 253
EN ++ + +F+ L+ LDLS+N++ + F +E+ + F
Sbjct: 61 ENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETF 120
Query: 254 SMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L+ L LYL N + D + +L +KL N
Sbjct: 121 RGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDN 158
>AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein.
Length = 673
Score = 91.9 bits (218), Expect = 2e-17
Identities = 78/308 (25%), Positives = 135/308 (43%), Gaps = 7/308 (2%)
Query: 62 FANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKL 120
FA L+ +D+S N++ +PS F L +L LDL+ N++ I N TF L+ L+ L L
Sbjct: 72 FAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYL 131
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
N+I +I AF+ N+L+ +P L L+ LDLS+N+L++L
Sbjct: 132 GKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPL---RLPRLLLLDLSHNSLLALEPGI 188
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXX 240
++ + L L L Q+ + FS NL LD+S N+L +
Sbjct: 189 LDTANV-EALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLA 247
Query: 241 XXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHAL 300
++ + + L L L + +LP P+L ++ + NP++C C
Sbjct: 248 GNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAARNPFNCVCPLS 307
Query: 301 YISAWVRLNEMKIWDYSPT-CVSPWYLEGHFLKKLKFPEL-CAGQWASMVNLSPRLPIQQ 358
+ WVR + + + T C P G L +L + + C + + R +++
Sbjct: 308 WFGPWVRESHVTLASPEETRCHFPPKNAGRLLLELDYADFGCPATTTTATVPTTRPVVRE 367
Query: 359 LLALNVSV 366
AL+ S+
Sbjct: 368 PTALSSSL 375
Score = 65.3 bits (152), Expect = 2e-09
Identities = 56/223 (25%), Positives = 99/223 (44%), Gaps = 5/223 (2%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+F+N + L G F L L+ L L +N + + S F L ++DL+ N L+ + +
Sbjct: 59 VFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNE 118
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKL 120
F LE + + NR+ ++ +F L L L L N+++ + L L +L L
Sbjct: 119 TFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALP--PLRLPRLLLLDL 176
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
S N + + + L+ + LF+ L+ L LD+S+N L + V
Sbjct: 177 SHNSLLALEPGILDTANVEALRLAGLG-LQQLDEGLFSRLRNLHDLDVSDNQLERVPPV- 234
Query: 181 FESLKLLRNLDLKENA-LSQIPDNTFSDCFNLEKLDLSKNKLR 222
L+ L L L N ++Q+ + L++LD+S L+
Sbjct: 235 IRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQ 277
Score = 50.0 bits (114), Expect = 9e-05
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 3/121 (2%)
Query: 171 NNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFY 230
N + L F L L+ LDL +N ++ +P F NL LDL+ N+L I F
Sbjct: 62 NGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFR 121
Query: 231 GXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSG 290
G + AF L L L L N +LP L P+L ++ LS
Sbjct: 122 GLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRL---PRLLLLDLSH 178
Query: 291 N 291
N
Sbjct: 179 N 179
Score = 37.5 bits (83), Expect = 0.51
Identities = 23/98 (23%), Positives = 41/98 (41%)
Query: 194 ENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAF 253
EN ++ + +F+ L+ LDLS+N++ + F +E+ + F
Sbjct: 61 ENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETF 120
Query: 254 SMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L+ L LYL N + D + +L +KL N
Sbjct: 121 RGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDN 158
>AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein.
Length = 887
Score = 91.9 bits (218), Expect = 2e-17
Identities = 69/219 (31%), Positives = 101/219 (46%), Gaps = 3/219 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L G FE L +L LRL N L + F L ++ L +N + L + FA
Sbjct: 217 NEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFA 276
Query: 64 NNTFLETIDISNNRVV--YVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKL 120
L +++S N + + +F L SL L LS N +Q++ F L L +L L
Sbjct: 277 QLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSL 336
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
N++ +++ AF + N+L +PT L L L LDLS N L +L
Sbjct: 337 RGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPAT 396
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
F L LR L L+ NALS + + F+ L +LDL N
Sbjct: 397 FGHLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGN 435
Score = 89.4 bits (212), Expect = 1e-16
Identities = 88/337 (26%), Positives = 126/337 (37%), Gaps = 5/337 (1%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F L L+ L LQ N + + + F +L + L NN L L A L +
Sbjct: 155 FHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYA 214
Query: 74 SNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNA 132
+ N + + SF GL SL L L N + + + F+ L NL L L N+I + NA
Sbjct: 215 NGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNA 274
Query: 133 FENXXXXXXXXXDRNKLKNI--PTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNL 190
F N+L+ F L+ L L LS N+L L F+ L L L
Sbjct: 275 FAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLL 334
Query: 191 DLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHF 250
L+ N L+ + F L +L L N+L + +H
Sbjct: 335 SLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHP 394
Query: 251 KAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVR--L 308
F L L L L N +L P L + L GN W CDC + W+
Sbjct: 395 ATFGHLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGNGWTCDCRLRGLKRWMGDWH 454
Query: 309 NEMKIWDYSPTCVSPWYLEGHFLKKLKFPELCAGQWA 345
++ ++ C P L G +L L +L G A
Sbjct: 455 SQGRLLTVFVQCRHPPALRGKYLDYLDDQQLQNGSCA 491
Score = 81.0 bits (191), Expect = 4e-14
Identities = 62/222 (27%), Positives = 104/222 (46%), Gaps = 3/222 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ L G L L+ L N + + +F + L + L N L LP+ +F
Sbjct: 192 NNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVF 251
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQ-NIQNG-TFS-LKNLQILK 119
A L + + +NR+ ++ ++F L L+ L+LS N++Q ++++ TF+ L++L L
Sbjct: 252 APLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLI 311
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
LS N + ++ F++ N+L ++ + F L+ L L L N L L
Sbjct: 312 LSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTA 371
Query: 180 EFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
E L L LDL N LS + TF L +L L N L
Sbjct: 372 LLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNAL 413
Score = 78.6 bits (185), Expect = 2e-13
Identities = 70/273 (25%), Positives = 114/273 (41%), Gaps = 3/273 (1%)
Query: 22 TLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYV 81
T L N++ I + F +L +DL N + +L K F + LE + + NN + +
Sbjct: 139 TYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQAL 198
Query: 82 PSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXX 140
+ L L+IL + N+I + G+F L++L L+L N + + D F
Sbjct: 199 APGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLL 258
Query: 141 XXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLM-SLA-GVEFESLKLLRNLDLKENALS 198
+ N+++ + F L L FL+LS N L SL F L+ L +L L N+L
Sbjct: 259 YLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQ 318
Query: 199 QIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKN 258
+ F L L L N+L + AF+G ++ L +
Sbjct: 319 HLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHS 378
Query: 259 LTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L L L GN +L T ++ +L + L N
Sbjct: 379 LEALDLSGNELSALHPATFGHLGRLRELSLRNN 411
Score = 72.9 bits (171), Expect = 1e-11
Identities = 62/222 (27%), Positives = 92/222 (41%), Gaps = 4/222 (1%)
Query: 74 SNNRVVYVPSDSFL-GLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDN 131
+N + VP S L + + L N I NI F L L+ L L N+I ++
Sbjct: 118 TNRGLRVVPKTSSLPSPHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPK 177
Query: 132 AFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLD 191
FE N L+ + L+ L L + N + L+ FE L+ L L
Sbjct: 178 TFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLR 237
Query: 192 LKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF--YGXXXXXXXXXXXXXXYEVH 249
L NAL +PD F+ NL L L N++RF+ AF G H
Sbjct: 238 LDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRH 297
Query: 250 FKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
F+ L++L++L L N L R ++P+L ++ L GN
Sbjct: 298 AATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGN 339
>BC068590-1|AAH68590.1| 778|Homo sapiens LOC150356 protein protein.
Length = 778
Score = 91.1 bits (216), Expect = 4e-17
Identities = 80/301 (26%), Positives = 118/301 (39%), Gaps = 7/301 (2%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI- 105
+DL N L +P F L +D+ + V V +F GL L +L+L+ N ++ +
Sbjct: 83 LDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELP 142
Query: 106 QNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
Q L +L+ L+L N + + F N L +P F L + +
Sbjct: 143 QEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRW 202
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
L LS+N L LA L LR L L N L +P S L +L+L N L +
Sbjct: 203 LRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAG 262
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
+ +AF+ L TL L GN +LP L +L
Sbjct: 263 EEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPP--LQGPGQLRR 320
Query: 286 VKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPEL-CAGQW 344
++L GNP C C A + W+ ++ C P L G L L+ +L C G
Sbjct: 321 LRLQGNPLWCGCQARPLLEWLARARVR---SDGACQGPRRLRGEALDALRPWDLRCPGDA 377
Query: 345 A 345
A
Sbjct: 378 A 378
Score = 86.2 bits (204), Expect = 1e-15
Identities = 66/222 (29%), Positives = 101/222 (45%), Gaps = 3/222 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH +P F L +L +L LQ + E+++ A +L ++ LS+N L L
Sbjct: 451 NHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALE 510
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L + + NR + VP + L SL L L N + + G + L+ + LS
Sbjct: 511 GAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLHDNAVDRLAPGDLGRTRALRWVYLSG 570
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I +S A DRN+L+ +PT L L+ L LS N L +L F+
Sbjct: 571 NRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQ 630
Query: 183 SL-KLLRNLDLKENALSQIPDNTFSDCF-NLEKLDLSKNKLR 222
+ + L++L L + L QI FS L+ L L KN+LR
Sbjct: 631 PVGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLR 672
Score = 70.9 bits (166), Expect = 4e-11
Identities = 81/306 (26%), Positives = 120/306 (39%), Gaps = 34/306 (11%)
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINN 127
+ +D+ N VP +F GL L L L I ++ G + L L L LSDN++
Sbjct: 444 QLLDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAG 503
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+S A E +RN+ +P L L L L +N + LA + + L
Sbjct: 504 LSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLHDNAVDRLAPGDLGRTRAL 563
Query: 188 R------------------------NLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRF 223
R L L N L ++P L +L LS N LR
Sbjct: 564 RWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRA 623
Query: 224 INITAFYGXXXXXXXXXXXXXXYE-VHFKAFSML-KNLTTLYLDGNMFPSLPSRTLDYMP 281
+ AF E + AFS L L +L+L N +LP+ L +
Sbjct: 624 LRDGAFQPVGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALPA--LPSLS 681
Query: 282 KLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFP-ELC 340
+L ++ LS NP+HCDC L + W+ +++ TC +P G +K E C
Sbjct: 682 QLELIDLSSNPFHCDCQLLPLHRWLTGLNLRV---GATCATPPNARGQRVKAAAAVFEDC 738
Query: 341 AGQWAS 346
G WA+
Sbjct: 739 PG-WAA 743
Score = 69.7 bits (163), Expect = 1e-10
Identities = 53/219 (24%), Positives = 101/219 (46%), Gaps = 1/219 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ +P F+ + +L L L+ +E + AF +L ++L++N+L LP++
Sbjct: 88 NLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALD 147
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L +++ N + + +F L +L L+L+ N + + F L ++ L+LS
Sbjct: 148 GLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSH 207
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N ++ ++ A N+L+ +P + + + L L+L +N L +
Sbjct: 208 NALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGL 267
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
+L LR L L AL + F+ C L LDL N+L
Sbjct: 268 ALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQL 306
Score = 69.3 bits (162), Expect = 1e-10
Identities = 54/224 (24%), Positives = 92/224 (41%), Gaps = 1/224 (0%)
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINN 127
+ +D+ N + +P+ +F G+ L LDL +++ + G F L L +L L+ N +
Sbjct: 81 QRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRE 140
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ A + + N L+ + F L L L+L++N L+ L + F+ L +
Sbjct: 141 LPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRV 200
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
R L L NALS + + L +L L N+L+ +
Sbjct: 201 RWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTY 260
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ L L L LDG +L R + P+L + L GN
Sbjct: 261 AGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGN 304
Score = 61.3 bits (142), Expect = 4e-08
Identities = 53/197 (26%), Positives = 79/197 (40%), Gaps = 1/197 (0%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
VE + G F L L L L N+L E+ EA L ++L N L L F
Sbjct: 114 VELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGAL 173
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI-QNGTFSLKNLQILKLSDNK 124
L T+++++N +VY+P+ +F GL ++ L LS N + + L L+ L L N+
Sbjct: 174 GALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNE 233
Query: 125 INNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESL 184
+ + N L + L L L L L +L F
Sbjct: 234 LQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHC 293
Query: 185 KLLRNLDLKENALSQIP 201
L LDL+ N L +P
Sbjct: 294 PRLHTLDLRGNQLDTLP 310
Score = 56.0 bits (129), Expect = 1e-06
Identities = 50/195 (25%), Positives = 86/195 (44%), Gaps = 3/195 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ LP + L +L+ L L+ N LEE+ F + L ++L++N L LP F
Sbjct: 136 NHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQ 195
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
+ + +S+N + + ++ GL +L+ L L N++Q + S + L L+L
Sbjct: 196 GLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGH 255
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + + D L+ + + F + L LDL N L +L ++
Sbjct: 256 NPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPPLQGP 315
Query: 183 SLKLLRNLDLKENAL 197
LR L L+ N L
Sbjct: 316 G--QLRRLRLQGNPL 328
Score = 49.6 bits (113), Expect = 1e-04
Identities = 50/196 (25%), Positives = 79/196 (40%), Gaps = 5/196 (2%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + L E L L L+RN ++ A + LF + L +N + L
Sbjct: 498 DNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLHDNAVDRLAPGDL 557
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
L + +S NR+ V + L+ L L +N+++ + G L L L+LS
Sbjct: 558 GRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLS 617
Query: 122 DNKINNISDNAFEN-XXXXXXXXXDRNKLKNIPTQLFNNL-KCLIFLDLSNNNLMSLAGV 179
N + + D AF+ + + L+ I F+ L L L L N L +L +
Sbjct: 618 GNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALPAL 677
Query: 180 EFESLKLLRNLDLKEN 195
SL L +DL N
Sbjct: 678 --PSLSQLELIDLSSN 691
Score = 36.7 bits (81), Expect = 0.90
Identities = 29/107 (27%), Positives = 43/107 (40%)
Query: 185 KLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXX 244
+L + LDL+ N L IP F +L LDL ++ + AF G
Sbjct: 78 ELTQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNH 137
Query: 245 XYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
E+ +A L +L L L+GN L T + L + L+ N
Sbjct: 138 LRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHN 184
>BC040188-1|AAH40188.1| 692|Homo sapiens LOC150356 protein protein.
Length = 692
Score = 91.1 bits (216), Expect = 4e-17
Identities = 80/301 (26%), Positives = 118/301 (39%), Gaps = 7/301 (2%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI- 105
+DL N L +P F L +D+ + V V +F GL L +L+L+ N ++ +
Sbjct: 73 LDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELP 132
Query: 106 QNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
Q L +L+ L+L N + + F N L +P F L + +
Sbjct: 133 QEALDGLGSLRRLELEGNALEGLRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRW 192
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
L LS+N L LA L LR L L N L +P S L +L+L N L +
Sbjct: 193 LRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAG 252
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
+ +AF+ L TL L GN +LP L +L
Sbjct: 253 EEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPP--LQGPGQLRR 310
Query: 286 VKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPEL-CAGQW 344
++L GNP C C A + W+ ++ C P L G L L+ +L C G
Sbjct: 311 LRLQGNPLWCGCQARPLLEWLARARVR---SDGACQGPRRLRGEALDALRPWDLRCPGDA 367
Query: 345 A 345
A
Sbjct: 368 A 368
Score = 87.8 bits (208), Expect = 4e-16
Identities = 67/222 (30%), Positives = 101/222 (45%), Gaps = 3/222 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH +P F L +L +L LQ + E+++ A +L +V LS+N L L
Sbjct: 441 NHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYVYLSDNQLAGLSAAALE 500
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L + + NR + VP + L SL L L N + + G + L+ + LS
Sbjct: 501 GAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSG 560
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I +S A DRN+L+ +PT L L+ L LS N L +L F+
Sbjct: 561 NRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQ 620
Query: 183 SL-KLLRNLDLKENALSQIPDNTFSDCF-NLEKLDLSKNKLR 222
+ + L++L L + L QI FS L+ L L KN+LR
Sbjct: 621 PVGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLR 662
Score = 69.3 bits (162), Expect = 1e-10
Identities = 54/224 (24%), Positives = 92/224 (41%), Gaps = 1/224 (0%)
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINN 127
+ +D+ N + +P+ +F G+ L LDL +++ + G F L L +L L+ N +
Sbjct: 71 QRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRE 130
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ A + + N L+ + F L L L+L++N L+ L + F+ L +
Sbjct: 131 LPQEALDGLGSLRRLELEGNALEGLRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRV 190
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
R L L NALS + + L +L L N+L+ +
Sbjct: 191 RWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTY 250
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ L L L LDG +L R + P+L + L GN
Sbjct: 251 AGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGN 294
Score = 69.3 bits (162), Expect = 1e-10
Identities = 53/219 (24%), Positives = 101/219 (46%), Gaps = 1/219 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ +P F+ + +L L L+ +E + AF +L ++L++N+L LP++
Sbjct: 78 NLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALD 137
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L +++ N + + +F L +L L+L+ N + + F L ++ L+LS
Sbjct: 138 GLGSLRRLELEGNALEGLRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSH 197
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N ++ ++ A N+L+ +P + + + L L+L +N L +
Sbjct: 198 NALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGL 257
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
+L LR L L AL + F+ C L LDL N+L
Sbjct: 258 ALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQL 296
Score = 60.9 bits (141), Expect = 5e-08
Identities = 53/197 (26%), Positives = 79/197 (40%), Gaps = 1/197 (0%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
VE + G F L L L L N+L E+ EA L ++L N L L F
Sbjct: 104 VELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEGLRPGTFGAL 163
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI-QNGTFSLKNLQILKLSDNK 124
L T+++++N +VY+P+ +F GL ++ L LS N + + L L+ L L N+
Sbjct: 164 GALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNE 223
Query: 125 INNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESL 184
+ + N L + L L L L L +L F
Sbjct: 224 LQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHC 283
Query: 185 KLLRNLDLKENALSQIP 201
L LDL+ N L +P
Sbjct: 284 PRLHTLDLRGNQLDTLP 300
Score = 59.7 bits (138), Expect = 1e-07
Identities = 45/164 (27%), Positives = 71/164 (43%), Gaps = 1/164 (0%)
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINN 127
+ +D+ N VP +F GL L L L I ++ G + L L + LSDN++
Sbjct: 434 QLLDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYVYLSDNQLAG 493
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+S A E +RN+ +P L L L L +N + LA + + L
Sbjct: 494 LSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRAL 553
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
R + L N ++++ LEKL L +N+LR + A G
Sbjct: 554 RWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEG 597
Score = 49.6 bits (113), Expect = 1e-04
Identities = 33/126 (26%), Positives = 57/126 (45%), Gaps = 1/126 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + YLP F+ L+ ++ LRL N L + EA L + L +N L LP + +
Sbjct: 174 NALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLS 233
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L +++ +N + Y + L L L+ L L +Q + F+ L L L
Sbjct: 234 QARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRG 293
Query: 123 NKINNI 128
N+++ +
Sbjct: 294 NQLDTL 299
Score = 48.0 bits (109), Expect = 4e-04
Identities = 42/177 (23%), Positives = 64/177 (36%)
Query: 116 QILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMS 175
Q+L L N ++ AF + + L LI++ LS+N L
Sbjct: 434 QLLDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYVYLSDNQLAG 493
Query: 176 LAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXX 235
L+ E L L L+ N Q+P +L L L N + +
Sbjct: 494 LSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRAL 553
Query: 236 XXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNP 292
EV A + L L+LD N +P+ L+ +P L ++LSGNP
Sbjct: 554 RWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNP 610
Score = 47.2 bits (107), Expect = 6e-04
Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 1/133 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + L E L L L+RN ++ A + LF + L +N + L
Sbjct: 488 DNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDL 547
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
L + +S NR+ V + L+ L L +N+++ + G L L L+LS
Sbjct: 548 GRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLS 607
Query: 122 DNKINNISDNAFE 134
N + + D AF+
Sbjct: 608 GNPLRALRDGAFQ 620
Score = 36.7 bits (81), Expect = 0.90
Identities = 29/107 (27%), Positives = 43/107 (40%)
Query: 185 KLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXX 244
+L + LDL+ N L IP F +L LDL ++ + AF G
Sbjct: 68 ELTQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNH 127
Query: 245 XYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
E+ +A L +L L L+GN L T + L + L+ N
Sbjct: 128 LRELPQEALDGLGSLRRLELEGNALEGLRPGTFGALGALATLNLAHN 174
>AL035681-1|CAI22653.1| 762|Homo sapiens protein ( Human DNA
sequence from clone RP4-756G23 on chromosome
22q13.31-13.33. ).
Length = 762
Score = 91.1 bits (216), Expect = 4e-17
Identities = 80/301 (26%), Positives = 118/301 (39%), Gaps = 7/301 (2%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI- 105
+DL N L +P F L +D+ + V V +F GL L +L+L+ N ++ +
Sbjct: 67 LDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELP 126
Query: 106 QNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
Q L +L+ L+L N + + F N L +P F L + +
Sbjct: 127 QEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRW 186
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
L LS+N L LA L LR L L N L +P S L +L+L N L +
Sbjct: 187 LRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAG 246
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
+ +AF+ L TL L GN +LP L +L
Sbjct: 247 EEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPP--LQGPGQLRR 304
Query: 286 VKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPEL-CAGQW 344
++L GNP C C A + W+ ++ C P L G L L+ +L C G
Sbjct: 305 LRLQGNPLWCGCQARPLLEWLARARVR---SDGACQGPRRLRGEALDALRPWDLRCPGDA 361
Query: 345 A 345
A
Sbjct: 362 A 362
Score = 86.6 bits (205), Expect = 8e-16
Identities = 66/222 (29%), Positives = 101/222 (45%), Gaps = 3/222 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH +P F L +L +L LQ + E+++ A +L ++ LS+N L L
Sbjct: 435 NHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALE 494
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L + + NR + VP + L SL L L N + + G + L+ + LS
Sbjct: 495 GAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSG 554
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I +S A DRN+L+ +PT L L+ L LS N L +L F+
Sbjct: 555 NRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQ 614
Query: 183 SL-KLLRNLDLKENALSQIPDNTFSDCF-NLEKLDLSKNKLR 222
+ + L++L L + L QI FS L+ L L KN+LR
Sbjct: 615 PVGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLR 656
Score = 71.3 bits (167), Expect = 3e-11
Identities = 81/306 (26%), Positives = 120/306 (39%), Gaps = 34/306 (11%)
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINN 127
+ +D+ N VP +F GL L L L I ++ G + L L L LSDN++
Sbjct: 428 QLLDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAG 487
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+S A E +RN+ +P L L L L +N + LA + + L
Sbjct: 488 LSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRAL 547
Query: 188 R------------------------NLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRF 223
R L L N L ++P L +L LS N LR
Sbjct: 548 RWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRA 607
Query: 224 INITAFYGXXXXXXXXXXXXXXYE-VHFKAFSML-KNLTTLYLDGNMFPSLPSRTLDYMP 281
+ AF E + AFS L L +L+L N +LP+ L +
Sbjct: 608 LRDGAFQPVGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALPA--LPSLS 665
Query: 282 KLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFP-ELC 340
+L ++ LS NP+HCDC L + W+ +++ TC +P G +K E C
Sbjct: 666 QLELIDLSSNPFHCDCQLLPLHRWLTGLNLRV---GATCATPPNARGQRVKAAAAVFEDC 722
Query: 341 AGQWAS 346
G WA+
Sbjct: 723 PG-WAA 727
Score = 69.7 bits (163), Expect = 1e-10
Identities = 53/219 (24%), Positives = 101/219 (46%), Gaps = 1/219 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ +P F+ + +L L L+ +E + AF +L ++L++N+L LP++
Sbjct: 72 NLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALD 131
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L +++ N + + +F L +L L+L+ N + + F L ++ L+LS
Sbjct: 132 GLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSH 191
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N ++ ++ A N+L+ +P + + + L L+L +N L +
Sbjct: 192 NALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGL 251
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
+L LR L L AL + F+ C L LDL N+L
Sbjct: 252 ALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQL 290
Score = 69.3 bits (162), Expect = 1e-10
Identities = 54/224 (24%), Positives = 92/224 (41%), Gaps = 1/224 (0%)
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINN 127
+ +D+ N + +P+ +F G+ L LDL +++ + G F L L +L L+ N +
Sbjct: 65 QRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRE 124
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ A + + N L+ + F L L L+L++N L+ L + F+ L +
Sbjct: 125 LPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRV 184
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
R L L NALS + + L +L L N+L+ +
Sbjct: 185 RWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTY 244
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ L L L LDG +L R + P+L + L GN
Sbjct: 245 AGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGN 288
Score = 61.3 bits (142), Expect = 4e-08
Identities = 53/197 (26%), Positives = 79/197 (40%), Gaps = 1/197 (0%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
VE + G F L L L L N+L E+ EA L ++L N L L F
Sbjct: 98 VELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGAL 157
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI-QNGTFSLKNLQILKLSDNK 124
L T+++++N +VY+P+ +F GL ++ L LS N + + L L+ L L N+
Sbjct: 158 GALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNE 217
Query: 125 INNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESL 184
+ + N L + L L L L L +L F
Sbjct: 218 LQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHC 277
Query: 185 KLLRNLDLKENALSQIP 201
L LDL+ N L +P
Sbjct: 278 PRLHTLDLRGNQLDTLP 294
Score = 56.0 bits (129), Expect = 1e-06
Identities = 50/195 (25%), Positives = 86/195 (44%), Gaps = 3/195 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ LP + L +L+ L L+ N LEE+ F + L ++L++N L LP F
Sbjct: 120 NHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQ 179
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
+ + +S+N + + ++ GL +L+ L L N++Q + S + L L+L
Sbjct: 180 GLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGH 239
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + + D L+ + + F + L LDL N L +L ++
Sbjct: 240 NPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPPLQGP 299
Query: 183 SLKLLRNLDLKENAL 197
LR L L+ N L
Sbjct: 300 G--QLRRLRLQGNPL 312
Score = 50.0 bits (114), Expect = 9e-05
Identities = 50/196 (25%), Positives = 79/196 (40%), Gaps = 5/196 (2%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + L E L L L+RN ++ A + LF + L +N + L
Sbjct: 482 DNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDL 541
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
L + +S NR+ V + L+ L L +N+++ + G L L L+LS
Sbjct: 542 GRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLS 601
Query: 122 DNKINNISDNAFEN-XXXXXXXXXDRNKLKNIPTQLFNNL-KCLIFLDLSNNNLMSLAGV 179
N + + D AF+ + + L+ I F+ L L L L N L +L +
Sbjct: 602 GNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALPAL 661
Query: 180 EFESLKLLRNLDLKEN 195
SL L +DL N
Sbjct: 662 --PSLSQLELIDLSSN 675
Score = 36.7 bits (81), Expect = 0.90
Identities = 29/107 (27%), Positives = 43/107 (40%)
Query: 185 KLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXX 244
+L + LDL+ N L IP F +L LDL ++ + AF G
Sbjct: 62 ELTQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNH 121
Query: 245 XYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
E+ +A L +L L L+GN L T + L + L+ N
Sbjct: 122 LRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHN 168
>BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein.
Length = 601
Score = 90.6 bits (215), Expect = 5e-17
Identities = 76/302 (25%), Positives = 133/302 (44%), Gaps = 7/302 (2%)
Query: 68 LETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKIN 126
L+ +D+S N++ +PS F L +L LDL+ N++ I N TF L+ L+ L L N+I
Sbjct: 6 LQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIR 65
Query: 127 NISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKL 186
+I AF+ N+L+ +P L L+ LDLS+N+L++L ++
Sbjct: 66 HIQPGAFDTLDRLLELKLQDNELRALPPL---RLPRLLLLDLSHNSLLALEPGILDTAN- 121
Query: 187 LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXY 246
+ L L L Q+ + FS NL LD+S N+L +
Sbjct: 122 VEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLAGNTRIA 181
Query: 247 EVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWV 306
++ + + L L L + +LP P+L ++ + NP++C C + WV
Sbjct: 182 QLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAARNPFNCVCPLSWFGPWV 241
Query: 307 RLNEMKIWDYSPT-CVSPWYLEGHFLKKLKFPEL-CAGQWASMVNLSPRLPIQQLLALNV 364
R + + + T C P G L +L + + C + + R +++ AL+
Sbjct: 242 RESHVTLASPEETRCHFPPKNAGRLLLELDYADFGCPATTTTATVPTTRPVVREPTALSS 301
Query: 365 SV 366
S+
Sbjct: 302 SL 303
Score = 72.9 bits (171), Expect = 1e-11
Identities = 55/229 (24%), Positives = 99/229 (43%), Gaps = 5/229 (2%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + LP G+F+ L NL L L N L EI +E F ++L + L N + + F
Sbjct: 14 NQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFD 73
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
L + + +N + +P L L L +LDLS N + ++ G N++ L+L+
Sbjct: 74 TLDRLLELKLQDNELRALPP---LRLPRLLLLDLSHNSLLALEPGILDTANVEALRLAGL 130
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLS-NNNLMSLAGVEFE 182
+ + + F N+L+ +P + L+ L L L+ N + L +
Sbjct: 131 GLQQLDEGLFSRLRNLHDLDVSDNQLERVP-PVIRGLRGLTRLRLAGNTRIAQLRPEDLA 189
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
L L+ LD+ +L +P + L L ++N + +++G
Sbjct: 190 GLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAARNPFNCVCPLSWFG 238
Score = 54.8 bits (126), Expect = 3e-06
Identities = 51/207 (24%), Positives = 91/207 (43%), Gaps = 5/207 (2%)
Query: 17 LVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNN 76
L L+ L L +N + + S F L ++DL+ N L+ + + F LE + + N
Sbjct: 3 LPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKN 62
Query: 77 RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENX 136
R+ ++ +F L L L L N+++ + L L +L LS N + + +
Sbjct: 63 RIRHIQPGAFDTLDRLLELKLQDNELRALP--PLRLPRLLLLDLSHNSLLALEPGILDTA 120
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
L+ + LF+ L+ L LD+S+N L + V L+ L L L N
Sbjct: 121 NVEALRLAGLG-LQQLDEGLFSRLRNLHDLDVSDNQLERVPPV-IRGLRGLTRLRLAGNT 178
Query: 197 -LSQIPDNTFSDCFNLEKLDLSKNKLR 222
++Q+ + L++LD+S L+
Sbjct: 179 RIAQLRPEDLAGLAALQELDVSNLSLQ 205
Score = 51.2 bits (117), Expect = 4e-05
Identities = 46/180 (25%), Positives = 72/180 (40%), Gaps = 5/180 (2%)
Query: 112 LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNN 171
L LQ+L LS N+I ++ F+ N+L I + F L+ L L L N
Sbjct: 3 LPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKN 62
Query: 172 NLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
+ + F++L L L L++N L +P L LDLS N L +
Sbjct: 63 RIRHIQPGAFDTLDRLLELKLQDNELRALPPLRLP---RLLLLDLSHNSLLALE-PGILD 118
Query: 232 XXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
++ FS L+NL L + N +P + + LT ++L+GN
Sbjct: 119 TANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPP-VIRGLRGLTRLRLAGN 177
>AY324323-1|AAQ97218.1| 479|Homo sapiens leucine-rich repeat
neuronal 6A protein.
Length = 479
Score = 90.6 bits (215), Expect = 5e-17
Identities = 88/332 (26%), Positives = 143/332 (43%), Gaps = 35/332 (10%)
Query: 12 GIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETI 71
G F +L NL+TL L+ N L+ I FT L +D+S N + L + +F + L+++
Sbjct: 5 GAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSL 64
Query: 72 DISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISD 130
++ +N +VY+ +F GL SL+ L L K + +I S L L +L+L IN I D
Sbjct: 65 EVGDNDLVYIFHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRD 124
Query: 131 NAFENXXXXXXXXXDR-NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRN 189
+F+ L + L L L +++ NL ++ + L LR
Sbjct: 125 YSFKRLYRLKVLEISHWPYLDTMTPNCLYGLN-LTSLSITHCNLTAVPYLAVRHLVYLRF 183
Query: 190 LDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVH 249
L+L N +S I + + L+++ L +L + AF G
Sbjct: 184 LNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRG------------------ 225
Query: 250 FKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYI--SAWVR 307
L L L + GN +L + L + L NP CDC L++ W R
Sbjct: 226 ------LNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPLACDCRLLWVFRRRW-R 278
Query: 308 LNEMKIWDYSPTCVSPWYLEGHFLKKLKFPEL 339
LN + PTC +P +++G K FP++
Sbjct: 279 LNFNR---QQPTCATPEFVQGKEFK--DFPDV 305
Score = 57.2 bits (132), Expect = 6e-07
Identities = 66/244 (27%), Positives = 103/244 (42%), Gaps = 10/244 (4%)
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ AF N N+LK IP +F L L LD+S N ++ L F+ L L
Sbjct: 2 VEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNL 61
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
++L++ +N L I FS +LE+L L K L I A
Sbjct: 62 KSLEVGDNDLVYIFHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINA 121
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVR 307
+ +F L L L + + +P L + T + + L + LS HC+ A+ A
Sbjct: 122 IRDYSFKRLYRLKVLEI--SHWPYLDTMTPNCLYGLNLTSLSIT--HCNLTAVPYLAVRH 177
Query: 308 LNEMKIWDYSPTCVSPWYLEG---HFLKKLKFPELCAGQWASMVNLSPRLPIQQLLALNV 364
L ++ + S +S +EG H L +L+ +L GQ A + + R + L LNV
Sbjct: 178 LVYLRFLNLSYNPIST--IEGSMLHELLRLQEIQLVGGQLAVVEPYAFR-GLNYLRVLNV 234
Query: 365 SVNR 368
S N+
Sbjct: 235 SGNQ 238
Score = 55.6 bits (128), Expect = 2e-06
Identities = 52/221 (23%), Positives = 92/221 (41%), Gaps = 3/221 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + L +F+ L NLK+L + N L I AF+ L + L L ++P +
Sbjct: 44 ENKIVILLDYMFQDLYNLKSLEVGDNDLVYIFHRAFSGLNSLEQLTLEKCNLTSIPTEAL 103
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ--NGTFSLKNLQILKL 120
++ L + + + + + SF LY L++L++S + N + L NL L +
Sbjct: 104 SHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGL-NLTSLSI 162
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
+ + + A + N + I + + L L + L L +
Sbjct: 163 THCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYA 222
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
F L LR L++ N L+ + ++ F NLE L L N L
Sbjct: 223 FRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 263
>AL512424-2|CAI14256.1| 380|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 380
Score = 89.4 bits (212), Expect = 1e-16
Identities = 55/179 (30%), Positives = 84/179 (46%), Gaps = 3/179 (1%)
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
L+L+ NN+ + +F LK LR L L EN + + F D LE+LDLS+N ++ I
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENAIQAIP 125
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
AF G + AF L+ L L L+ N ++P + ++MPKL
Sbjct: 126 RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRT 185
Query: 286 VKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPEL-CAGQ 343
+L N CDCH ++S W+R + C P L G + +++ E C+GQ
Sbjct: 186 FRLHSNHLFCDCHLAWLSQWLR--QRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQ 242
Score = 62.9 bits (146), Expect = 1e-08
Identities = 36/118 (30%), Positives = 60/118 (50%), Gaps = 1/118 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L N + I F K+L + L N + + F + LE +D+S N +
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENAI 121
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFEN 135
+P +F G L+ L L KN+I I+ G F +L+ L++L L++N I I ++F +
Sbjct: 122 QAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNH 179
Score = 62.9 bits (146), Expect = 1e-08
Identities = 33/123 (26%), Positives = 61/123 (49%), Gaps = 1/123 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ + F L L+ L+L N + ++ AF K+L +DLS N + +P K F
Sbjct: 71 NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENAIQAIPRKAFR 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
T L+ + + N++ + +F L L++L L+ N I I +F+ + L+ +L
Sbjct: 131 GATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHS 190
Query: 123 NKI 125
N +
Sbjct: 191 NHL 193
Score = 56.0 bits (129), Expect = 1e-06
Identities = 36/128 (28%), Positives = 59/128 (46%), Gaps = 1/128 (0%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
L+L+ N I I F+ LK L++L+L +N+I + AF++ N ++ IP
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENAIQAIP 125
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
+ F L L L N + + F +L+ L L L N ++ IP ++F+ L
Sbjct: 126 RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRT 185
Query: 214 LDLSKNKL 221
L N L
Sbjct: 186 FRLHSNHL 193
Score = 55.6 bits (128), Expect = 2e-06
Identities = 30/88 (34%), Positives = 49/88 (55%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
+RL+ N ++ I AF+ +KL +DLSNN + + F L ++ + N++ +P
Sbjct: 290 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 349
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTF 110
F GLY+LQ+L L+ NKI I+ F
Sbjct: 350 RGVFGGLYTLQLLLLNANKINCIRPDAF 377
Score = 53.2 bits (122), Expect = 1e-05
Identities = 33/117 (28%), Positives = 55/117 (47%)
Query: 113 KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNN 172
+N + L+L+ N I I N F N++ + F+++K L LDLS N
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENA 120
Query: 173 LMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
+ ++ F L+NL L +N +S I + F LE L L+ N + I +++F
Sbjct: 121 IQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSF 177
Score = 52.4 bits (120), Expect = 2e-05
Identities = 56/276 (20%), Positives = 100/276 (36%), Gaps = 9/276 (3%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N + + G F+ + L+ L L N ++ I +AF L ++ L N + + E
Sbjct: 92 LMENQIGAVERGAFDDMKELERLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEG 151
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI-QNIQNGTFS--LKNLQI 117
F LE + ++NN + +P SF + L+ L N + + S L+
Sbjct: 152 AFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPT 211
Query: 118 LKLSDNKINNISDNAFE--NXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL-- 173
+ L S + + +PT ++ C SN +
Sbjct: 212 IGLFTQCSGPASLRGLNVAEVQKSEFSCSGQGEAGRVPTCTLSSGSCPAMCTCSNGIVDC 271
Query: 174 --MSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
L + + + + L+ N + IP FS L ++DLS N++ I AF G
Sbjct: 272 RGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG 331
Query: 232 XXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGN 267
++ F L L L L+ N
Sbjct: 332 LRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNAN 367
Score = 51.6 bits (118), Expect = 3e-05
Identities = 28/83 (33%), Positives = 45/83 (54%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N +K+IP F+ + L +DLSNN + +A F+ L+ L +L L N ++ +P F
Sbjct: 295 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 354
Query: 207 DCFNLEKLDLSKNKLRFINITAF 229
+ L+ L L+ NK+ I AF
Sbjct: 355 GLYTLQLLLLNANKINCIRPDAF 377
Score = 39.5 bits (88), Expect = 0.13
Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 97 LSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQ 155
L N I++I G FS + L+ + LS+N+I I+ +AF+ NK+ ++P
Sbjct: 292 LELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRG 351
Query: 156 LFNNLKCLIFLDLSNNNLMSLAGVEFESL 184
+F L L L L+ N + + F+ L
Sbjct: 352 VFGGLYTLQLLLLNANKINCIRPDAFQDL 380
Score = 39.5 bits (88), Expect = 0.13
Identities = 22/86 (25%), Positives = 41/86 (47%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ +P G F L+ + L N + EI +AF + L + L N + LP +F
Sbjct: 295 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 354
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGL 89
L+ + ++ N++ + D+F L
Sbjct: 355 GLYTLQLLLLNANKINCIRPDAFQDL 380
>BC043165-1|AAH43165.1| 719|Homo sapiens leucine rich repeat and
fibronectin type III domain containing 5 protein.
Length = 719
Score = 88.6 bits (210), Expect = 2e-16
Identities = 83/303 (27%), Positives = 115/303 (37%), Gaps = 20/303 (6%)
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
L+L+DN + NI F N RN + I F +L+ L L L++N L +
Sbjct: 56 LRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKIT 115
Query: 178 GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXX 237
F L L +L L N L+ I F D F LE+LDLS N L I A
Sbjct: 116 NDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHT 175
Query: 238 XXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTL-----------DYMPKLTIV 286
+ FS L +T L + N LP L P +
Sbjct: 176 LSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFAL 235
Query: 287 KLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPE-LCAGQWA 345
GNP HC+C L++ R ++++ TC SP L G + + E LC
Sbjct: 236 SFGGNPLHCNCELLWLRRLSREDDLE------TCASPPLLTGRYFWSIPEEEFLCEPPLI 289
Query: 346 SMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWPIPVSESILDTHTGYVLDRGTTDIEDIT 405
+ R+ Q L R + I W P + I + V D GT DI IT
Sbjct: 290 TRHTHEMRVLEGQRATLRCKA-RGDPEPAIHWISPEGKLISNATRSLVYDNGTLDIL-IT 347
Query: 406 TIR 408
T++
Sbjct: 348 TVK 350
Score = 77.4 bits (182), Expect = 5e-13
Identities = 47/151 (31%), Positives = 77/151 (50%), Gaps = 1/151 (0%)
Query: 73 ISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDN 131
+++N V + F + SL L LS+N I I F+ L+NL+ L L+ N++ I+++
Sbjct: 58 LADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITND 117
Query: 132 AFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLD 191
F + N+L I + F+++ L LDLS NNL ++ E + L L
Sbjct: 118 MFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLS 177
Query: 192 LKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
L N + IP TFS + +LD++ NKL+
Sbjct: 178 LDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQ 208
Score = 77.0 bits (181), Expect = 7e-13
Identities = 45/161 (27%), Positives = 80/161 (49%), Gaps = 1/161 (0%)
Query: 42 KKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNK 101
++ + L++N++ + K FAN T L + +S N + ++ +F L +L+ L L+ N+
Sbjct: 51 RRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNR 110
Query: 102 IQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNL 160
+ I N FS L NL L L++N++ IS AF++ N L+ IP +
Sbjct: 111 LTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKM 170
Query: 161 KCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
L L L +N + ++ F L + LD+ N L ++P
Sbjct: 171 VSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLP 211
Score = 71.7 bits (168), Expect = 3e-11
Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + ++ F L NL+ L L N L +I ++ F+ L H+ L+NN L + F
Sbjct: 85 NTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFD 144
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
+ LE +D+S N + +P D+ + SL L L N I NI GTFS L + L ++
Sbjct: 145 DVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTS 204
Query: 123 NKINNI 128
NK+ +
Sbjct: 205 NKLQKL 210
Score = 70.1 bits (164), Expect = 8e-11
Identities = 45/155 (29%), Positives = 76/155 (49%), Gaps = 1/155 (0%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
LRL N++ I + F + L + LS N + + FA+ L + +++NR+ +
Sbjct: 56 LRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKIT 115
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXX 141
+D F GL +L L L+ N++ I + F + L+ L LS N + I +A E
Sbjct: 116 NDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHT 175
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSL 176
D N + NIP F++L + LD+++N L L
Sbjct: 176 LSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKL 210
Score = 67.7 bits (158), Expect = 4e-10
Identities = 44/163 (26%), Positives = 78/163 (47%), Gaps = 2/163 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN V + F ++ +L L L RN + I AF + L + L++N L + +F
Sbjct: 60 DNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMF 119
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ-NGTFSLKNLQILKLS 121
+ + L + ++NN++ + S +F +++L+ LDLS N ++ I + + +L L L
Sbjct: 120 SGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLD 179
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQ-LFNNLKCL 163
N I+NI F + NKL+ +P LF + L
Sbjct: 180 HNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVL 222
>AK055365-1|BAB70910.1| 719|Homo sapiens protein ( Homo sapiens
cDNA FLJ30803 fis, clone FEBRA2001245, weakly similar to
NAG14. ).
Length = 719
Score = 88.6 bits (210), Expect = 2e-16
Identities = 83/303 (27%), Positives = 115/303 (37%), Gaps = 20/303 (6%)
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
L+L+DN + NI F N RN + I F +L+ L L L++N L +
Sbjct: 56 LRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKIT 115
Query: 178 GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXX 237
F L L +L L N L+ I F D F LE+LDLS N L I A
Sbjct: 116 NDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHT 175
Query: 238 XXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTL-----------DYMPKLTIV 286
+ FS L +T L + N LP L P +
Sbjct: 176 LSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFAL 235
Query: 287 KLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPE-LCAGQWA 345
GNP HC+C L++ R ++++ TC SP L G + + E LC
Sbjct: 236 SFGGNPLHCNCELLWLRRLSREDDLE------TCASPPLLTGRYFWSIPEEEFLCEPPLI 289
Query: 346 SMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWPIPVSESILDTHTGYVLDRGTTDIEDIT 405
+ R+ Q L R + I W P + I + V D GT DI IT
Sbjct: 290 TRHTHEMRVLEGQRATLRCKA-RGDPEPAIHWISPEGKLISNATRSLVYDNGTLDIL-IT 347
Query: 406 TIR 408
T++
Sbjct: 348 TVK 350
Score = 77.4 bits (182), Expect = 5e-13
Identities = 47/151 (31%), Positives = 77/151 (50%), Gaps = 1/151 (0%)
Query: 73 ISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDN 131
+++N V + F + SL L LS+N I I F+ L+NL+ L L+ N++ I+++
Sbjct: 58 LADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITND 117
Query: 132 AFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLD 191
F + N+L I + F+++ L LDLS NNL ++ E + L L
Sbjct: 118 MFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLS 177
Query: 192 LKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
L N + IP TFS + +LD++ NKL+
Sbjct: 178 LDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQ 208
Score = 77.0 bits (181), Expect = 7e-13
Identities = 45/161 (27%), Positives = 80/161 (49%), Gaps = 1/161 (0%)
Query: 42 KKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNK 101
++ + L++N++ + K FAN T L + +S N + ++ +F L +L+ L L+ N+
Sbjct: 51 RRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNR 110
Query: 102 IQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNL 160
+ I N FS L NL L L++N++ IS AF++ N L+ IP +
Sbjct: 111 LTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKM 170
Query: 161 KCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
L L L +N + ++ F L + LD+ N L ++P
Sbjct: 171 VSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLP 211
Score = 71.7 bits (168), Expect = 3e-11
Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + ++ F L NL+ L L N L +I ++ F+ L H+ L+NN L + F
Sbjct: 85 NTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFD 144
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
+ LE +D+S N + +P D+ + SL L L N I NI GTFS L + L ++
Sbjct: 145 DVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTS 204
Query: 123 NKINNI 128
NK+ +
Sbjct: 205 NKLQKL 210
Score = 70.1 bits (164), Expect = 8e-11
Identities = 45/155 (29%), Positives = 76/155 (49%), Gaps = 1/155 (0%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
LRL N++ I + F + L + LS N + + FA+ L + +++NR+ +
Sbjct: 56 LRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKIT 115
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXX 141
+D F GL +L L L+ N++ I + F + L+ L LS N + I +A E
Sbjct: 116 NDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHT 175
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSL 176
D N + NIP F++L + LD+++N L L
Sbjct: 176 LSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKL 210
Score = 67.7 bits (158), Expect = 4e-10
Identities = 44/163 (26%), Positives = 78/163 (47%), Gaps = 2/163 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN V + F ++ +L L L RN + I AF + L + L++N L + +F
Sbjct: 60 DNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMF 119
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ-NGTFSLKNLQILKLS 121
+ + L + ++NN++ + S +F +++L+ LDLS N ++ I + + +L L L
Sbjct: 120 SGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLD 179
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQ-LFNNLKCL 163
N I+NI F + NKL+ +P LF + L
Sbjct: 180 HNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVL 222
>AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein.
Length = 1523
Score = 88.2 bits (209), Expect = 3e-16
Identities = 54/184 (29%), Positives = 87/184 (47%), Gaps = 2/184 (1%)
Query: 145 DRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNT 204
DRN + I F LK L L L +N + + F+ LK L L L +N L +P+
Sbjct: 69 DRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELL 128
Query: 205 FSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYL 264
F L +LDLS+N+++ I AF G + AF L++L L L
Sbjct: 129 FQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTL 188
Query: 265 DGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPW 324
+ N + + ++MPK+ ++L N +CDCH ++S W+R + + C++P
Sbjct: 189 NNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLR--QRRTVGQFTLCMAPV 246
Query: 325 YLEG 328
+L G
Sbjct: 247 HLRG 250
Score = 85.8 bits (203), Expect = 1e-15
Identities = 85/404 (21%), Positives = 171/404 (42%), Gaps = 22/404 (5%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
++ N + + G+F+ LV+L+ L L N + + F + L + L +N L T+ +
Sbjct: 362 LYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKG 421
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKL 120
LFA ++T+ ++ N V +L Y LQ + + + + K + +K
Sbjct: 422 LFAPLQSIQTLHLAQNPFVCDCHLKWLADY-LQDNPIETSGARCSSPRRLANKRISQIKS 480
Query: 121 -------SDNKINNISDNAFENXX-------XXXXXXXDRNKLKNIPTQLFNNLKCLIFL 166
S++ + S F + KL IP+ L + L
Sbjct: 481 KKFRCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLN 540
Query: 167 DLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINI 226
D + +++ G+ F+ L LR ++L N + ++ + F ++++L L+ N+L ++
Sbjct: 541 D-NEVSVLEATGI-FKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHG 598
Query: 227 TAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIV 286
F G V F+ L ++ L L N ++ + L+ +
Sbjct: 599 RVFRGLSGLKTLMLRSNLISCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTI 658
Query: 287 KLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPEL-CAGQWA 345
L NP++C+CH ++ W+R + +I +P C P++L+ ++ + + C G
Sbjct: 659 NLLSNPFNCNCHLAWLGKWLR--KRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEE 716
Query: 346 SMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWPIPVSESILDTH 389
S LSPR P +Q + +V RC G+ P + + + + +
Sbjct: 717 SSCQLSPRCP-EQCTCME-TVVRCSNKGLRALPRGMPKDVTELY 758
Score = 80.2 bits (189), Expect = 7e-14
Identities = 47/136 (34%), Positives = 72/136 (52%), Gaps = 1/136 (0%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
LDL +N I I F+ LKNL++L L DN+++ I AF++ ++NKL+ +P
Sbjct: 66 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLP 125
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
LF + L LDLS N + + F + ++NL L N +S I D F +LE
Sbjct: 126 ELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEI 185
Query: 214 LDLSKNKLRFINITAF 229
L L+ N + I +T+F
Sbjct: 186 LTLNNNNISRILVTSF 201
Score = 79.0 bits (186), Expect = 2e-13
Identities = 43/123 (34%), Positives = 71/123 (57%), Gaps = 1/123 (0%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F L NL+ L L+ N + I+ AF K+L + L+ N L LPE LF + L +D+
Sbjct: 81 FAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDL 140
Query: 74 SNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNA 132
S N++ +P +F G+ ++ L L N I I++G F +L++L+IL L++N I+ I +
Sbjct: 141 SENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTS 200
Query: 133 FEN 135
F +
Sbjct: 201 FNH 203
Score = 74.5 bits (175), Expect = 4e-12
Identities = 40/124 (32%), Positives = 65/124 (52%), Gaps = 1/124 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN V + G F+ L L+ LRL +N L+ + F ST KL +DLS N + +P K F
Sbjct: 94 DNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAF 153
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
T ++ + + NN + + +F L L+IL L+ N I I +F+ + ++ L+L
Sbjct: 154 RGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLH 213
Query: 122 DNKI 125
N +
Sbjct: 214 SNHL 217
Score = 73.7 bits (173), Expect = 6e-12
Identities = 42/154 (27%), Positives = 76/154 (49%), Gaps = 1/154 (0%)
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINN 127
E +D+ N + + F GL +L++L L N++ I+ G F LK L+ L+L+ NK+
Sbjct: 64 ERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQV 123
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + F++ N+++ IP + F + + L L NN++ + F +L+ L
Sbjct: 124 LPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDL 183
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
L L N +S+I +F+ + L L N L
Sbjct: 184 EILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 73.3 bits (172), Expect = 8e-12
Identities = 43/126 (34%), Positives = 69/126 (54%), Gaps = 4/126 (3%)
Query: 9 LPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFL 68
+P + E +V + RL++N ++ I + AFT KKL +D+S N + + F L
Sbjct: 301 IPANLPEGIVEI---RLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSL 357
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINN 127
++ + N++ + F GL SLQ+L L+ NKI ++ TF L+NL +L L DNK+
Sbjct: 358 TSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQT 417
Query: 128 ISDNAF 133
IS F
Sbjct: 418 ISKGLF 423
Score = 68.9 bits (161), Expect = 2e-10
Identities = 81/314 (25%), Positives = 136/314 (43%), Gaps = 41/314 (13%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N +E + G +F L LKTL L+ N + + ++ F + + L +N + T+ F
Sbjct: 591 NQLETVHGRVFRGLSGLKTLMLRSNLISCVSNDTFAGLSSVRLLSLYDNRITTITPGAFT 650
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLS-- 121
L TI++ +N ++LG + + +S N Q F LK + I ++
Sbjct: 651 TLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNP--RCQK-PFFLKEIPIQDVAIQ 707
Query: 122 -------DNKINNISDNAFENXXXXXXXXXDRNK-LKNIPTQLFNNLKCLIFLDLSNNNL 173
+ +S E NK L+ +P + K + L L N+L
Sbjct: 708 DFTCDGNEESSCQLSPRCPEQCTCMETVVRCSNKGLRALPRGM---PKDVTELYLEGNHL 764
Query: 174 MSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXX 233
++ E +L+ L +DL N++S + + TFS+ +L L LS N+LR I
Sbjct: 765 TAVPR-ELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCI--------- 814
Query: 234 XXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPW 293
VH AF+ L++L L L GN S+P + + + L+ + L NP
Sbjct: 815 -------------PVH--AFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 859
Query: 294 HCDCHALYISAWVR 307
HCDC ++S WV+
Sbjct: 860 HCDCSLRWLSEWVK 873
Score = 62.1 bits (144), Expect = 2e-08
Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 1/156 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L RN + I F K L + L +N + + F + LE + ++ N++
Sbjct: 62 NAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKL 121
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXX 137
+P F L LDLS+N+IQ I F + +++ L+L +N I+ I D AF
Sbjct: 122 QVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALR 181
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ N + I FN++ + L L +N+L
Sbjct: 182 DLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 61.7 bits (143), Expect = 3e-08
Identities = 34/121 (28%), Positives = 64/121 (52%), Gaps = 1/121 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ +P G F LK + + +N + +I +AF K L + L N + + + LF
Sbjct: 317 NSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFD 376
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L+ + ++ N++ + ++F L +L +L L NK+Q I G F+ L+++Q L L+
Sbjct: 377 GLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQ 436
Query: 123 N 123
N
Sbjct: 437 N 437
Score = 56.4 bits (130), Expect = 1e-06
Identities = 40/181 (22%), Positives = 77/181 (42%), Gaps = 3/181 (1%)
Query: 163 LIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
++ + L N++ ++ F K L+ +D+ +N +S I + F +L L L NK+
Sbjct: 309 IVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKIT 368
Query: 223 FINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPK 282
I F G + F L+NL L L N ++ +
Sbjct: 369 EIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQS 428
Query: 283 LTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPEL-CA 341
+ + L+ NP+ CDCH +++ +++ N ++ C SP L + ++K + C+
Sbjct: 429 IQTLHLAQNPFVCDCHLKWLADYLQDNPIE--TSGARCSSPRRLANKRISQIKSKKFRCS 486
Query: 342 G 342
G
Sbjct: 487 G 487
Score = 56.0 bits (129), Expect = 1e-06
Identities = 40/150 (26%), Positives = 74/150 (49%), Gaps = 4/150 (2%)
Query: 71 IDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS 129
+D ++ +P++ G+ ++ L +N I+ I G F+ K L+ + +S N+I++I+
Sbjct: 291 VDCRGKGLMEIPANLPEGIVEIR---LEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIA 347
Query: 130 DNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRN 189
+AF+ NK+ I LF+ L L L L+ N + L F+ L+ L
Sbjct: 348 PDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNL 407
Query: 190 LDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
L L +N L I F+ +++ L L++N
Sbjct: 408 LSLYDNKLQTISKGLFAPLQSIQTLHLAQN 437
Score = 52.0 bits (119), Expect = 2e-05
Identities = 34/108 (31%), Positives = 49/108 (45%)
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
++L N I I AF +N++ +I F LK L L L N + +A
Sbjct: 312 IRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIA 371
Query: 178 GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
F+ L L+ L L N ++ + NTF D NL L L NKL+ I+
Sbjct: 372 KGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTIS 419
>AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein.
Length = 1523
Score = 88.2 bits (209), Expect = 3e-16
Identities = 54/184 (29%), Positives = 87/184 (47%), Gaps = 2/184 (1%)
Query: 145 DRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNT 204
DRN + I F LK L L L +N + + F+ LK L L L +N L +P+
Sbjct: 69 DRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELL 128
Query: 205 FSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYL 264
F L +LDLS+N+++ I AF G + AF L++L L L
Sbjct: 129 FQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTL 188
Query: 265 DGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPW 324
+ N + + ++MPK+ ++L N +CDCH ++S W+R + + C++P
Sbjct: 189 NNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLR--QRRTVGQFTLCMAPV 246
Query: 325 YLEG 328
+L G
Sbjct: 247 HLRG 250
Score = 85.4 bits (202), Expect = 2e-15
Identities = 85/404 (21%), Positives = 171/404 (42%), Gaps = 22/404 (5%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
++ N + + G+F+ LV+L+ L L N + + F + L + L +N L T+ +
Sbjct: 362 LYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKG 421
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKL 120
LFA ++T+ ++ N V +L Y LQ + + + + K + +K
Sbjct: 422 LFAPLQSIQTLHLAQNPFVCDCHLKWLADY-LQDNPIETSGARCSSPRRLANKRISQIKS 480
Query: 121 -------SDNKINNISDNAFENXX-------XXXXXXXDRNKLKNIPTQLFNNLKCLIFL 166
S++ + S F + KL IP+ L + L
Sbjct: 481 KKFRCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLN 540
Query: 167 DLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINI 226
D + +++ G+ F+ L LR ++L N + ++ + F ++++L L+ N+L ++
Sbjct: 541 D-NEVSVLEATGI-FKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHG 598
Query: 227 TAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIV 286
F G V F+ L ++ L L N ++ + L+ +
Sbjct: 599 RVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTI 658
Query: 287 KLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPEL-CAGQWA 345
L NP++C+CH ++ W+R + +I +P C P++L+ ++ + + C G
Sbjct: 659 NLLSNPFNCNCHLAWLGKWLR--KRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEE 716
Query: 346 SMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWPIPVSESILDTH 389
S LSPR P +Q + +V RC G+ P + + + + +
Sbjct: 717 SSCQLSPRCP-EQCTCME-TVVRCSNKGLRALPRGMPKDVTELY 758
Score = 80.2 bits (189), Expect = 7e-14
Identities = 47/136 (34%), Positives = 72/136 (52%), Gaps = 1/136 (0%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
LDL +N I I F+ LKNL++L L DN+++ I AF++ ++NKL+ +P
Sbjct: 66 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLP 125
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
LF + L LDLS N + + F + ++NL L N +S I D F +LE
Sbjct: 126 ELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEI 185
Query: 214 LDLSKNKLRFINITAF 229
L L+ N + I +T+F
Sbjct: 186 LTLNNNNISRILVTSF 201
Score = 79.0 bits (186), Expect = 2e-13
Identities = 43/123 (34%), Positives = 71/123 (57%), Gaps = 1/123 (0%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F L NL+ L L+ N + I+ AF K+L + L+ N L LPE LF + L +D+
Sbjct: 81 FAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDL 140
Query: 74 SNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNA 132
S N++ +P +F G+ ++ L L N I I++G F +L++L+IL L++N I+ I +
Sbjct: 141 SENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTS 200
Query: 133 FEN 135
F +
Sbjct: 201 FNH 203
Score = 74.5 bits (175), Expect = 4e-12
Identities = 40/124 (32%), Positives = 65/124 (52%), Gaps = 1/124 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN V + G F+ L L+ LRL +N L+ + F ST KL +DLS N + +P K F
Sbjct: 94 DNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAF 153
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
T ++ + + NN + + +F L L+IL L+ N I I +F+ + ++ L+L
Sbjct: 154 RGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLH 213
Query: 122 DNKI 125
N +
Sbjct: 214 SNHL 217
Score = 73.7 bits (173), Expect = 6e-12
Identities = 42/154 (27%), Positives = 76/154 (49%), Gaps = 1/154 (0%)
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINN 127
E +D+ N + + F GL +L++L L N++ I+ G F LK L+ L+L+ NK+
Sbjct: 64 ERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQV 123
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + F++ N+++ IP + F + + L L NN++ + F +L+ L
Sbjct: 124 LPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDL 183
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
L L N +S+I +F+ + L L N L
Sbjct: 184 EILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 73.3 bits (172), Expect = 8e-12
Identities = 43/126 (34%), Positives = 69/126 (54%), Gaps = 4/126 (3%)
Query: 9 LPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFL 68
+P + E +V + RL++N ++ I + AFT KKL +D+S N + + F L
Sbjct: 301 IPANLPEGIVEI---RLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSL 357
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINN 127
++ + N++ + F GL SLQ+L L+ NKI ++ TF L+NL +L L DNK+
Sbjct: 358 TSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQT 417
Query: 128 ISDNAF 133
IS F
Sbjct: 418 ISKGLF 423
Score = 68.1 bits (159), Expect = 3e-10
Identities = 81/314 (25%), Positives = 136/314 (43%), Gaps = 41/314 (13%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N +E + G +F L LKTL L+ N + + ++ F + + L +N + T+ F
Sbjct: 591 NQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFT 650
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLS-- 121
L TI++ +N ++LG + + +S N Q F LK + I ++
Sbjct: 651 TLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNP--RCQK-PFFLKEIPIQDVAIQ 707
Query: 122 -------DNKINNISDNAFENXXXXXXXXXDRNK-LKNIPTQLFNNLKCLIFLDLSNNNL 173
+ +S E NK L+ +P + K + L L N+L
Sbjct: 708 DFTCDGNEESSCQLSPRCPEQCTCMETVVRCSNKGLRALPRGM---PKDVTELYLEGNHL 764
Query: 174 MSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXX 233
++ E +L+ L +DL N++S + + TFS+ +L L LS N+LR I
Sbjct: 765 TAVPR-ELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCI--------- 814
Query: 234 XXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPW 293
VH AF+ L++L L L GN S+P + + + L+ + L NP
Sbjct: 815 -------------PVH--AFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 859
Query: 294 HCDCHALYISAWVR 307
HCDC ++S WV+
Sbjct: 860 HCDCSLRWLSEWVK 873
Score = 62.1 bits (144), Expect = 2e-08
Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 1/156 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L RN + I F K L + L +N + + F + LE + ++ N++
Sbjct: 62 NAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKL 121
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXX 137
+P F L LDLS+N+IQ I F + +++ L+L +N I+ I D AF
Sbjct: 122 QVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALR 181
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ N + I FN++ + L L +N+L
Sbjct: 182 DLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 61.7 bits (143), Expect = 3e-08
Identities = 34/121 (28%), Positives = 64/121 (52%), Gaps = 1/121 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ +P G F LK + + +N + +I +AF K L + L N + + + LF
Sbjct: 317 NSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFD 376
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L+ + ++ N++ + ++F L +L +L L NK+Q I G F+ L+++Q L L+
Sbjct: 377 GLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQ 436
Query: 123 N 123
N
Sbjct: 437 N 437
Score = 56.4 bits (130), Expect = 1e-06
Identities = 40/181 (22%), Positives = 77/181 (42%), Gaps = 3/181 (1%)
Query: 163 LIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
++ + L N++ ++ F K L+ +D+ +N +S I + F +L L L NK+
Sbjct: 309 IVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKIT 368
Query: 223 FINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPK 282
I F G + F L+NL L L N ++ +
Sbjct: 369 EIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQS 428
Query: 283 LTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPEL-CA 341
+ + L+ NP+ CDCH +++ +++ N ++ C SP L + ++K + C+
Sbjct: 429 IQTLHLAQNPFVCDCHLKWLADYLQDNPIE--TSGARCSSPRRLANKRISQIKSKKFRCS 486
Query: 342 G 342
G
Sbjct: 487 G 487
Score = 56.0 bits (129), Expect = 1e-06
Identities = 40/150 (26%), Positives = 74/150 (49%), Gaps = 4/150 (2%)
Query: 71 IDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS 129
+D ++ +P++ G+ ++ L +N I+ I G F+ K L+ + +S N+I++I+
Sbjct: 291 VDCRGKGLMEIPANLPEGIVEIR---LEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIA 347
Query: 130 DNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRN 189
+AF+ NK+ I LF+ L L L L+ N + L F+ L+ L
Sbjct: 348 PDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNL 407
Query: 190 LDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
L L +N L I F+ +++ L L++N
Sbjct: 408 LSLYDNKLQTISKGLFAPLQSIQTLHLAQN 437
Score = 52.0 bits (119), Expect = 2e-05
Identities = 34/108 (31%), Positives = 49/108 (45%)
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
++L N I I AF +N++ +I F LK L L L N + +A
Sbjct: 312 IRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIA 371
Query: 178 GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
F+ L L+ L L N ++ + NTF D NL L L NKL+ I+
Sbjct: 372 KGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTIS 419
>AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein.
Length = 1559
Score = 88.2 bits (209), Expect = 3e-16
Identities = 54/184 (29%), Positives = 87/184 (47%), Gaps = 2/184 (1%)
Query: 145 DRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNT 204
DRN + I F LK L L L +N + + F+ LK L L L +N L +P+
Sbjct: 105 DRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELL 164
Query: 205 FSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYL 264
F L +LDLS+N+++ I AF G + AF L++L L L
Sbjct: 165 FQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTL 224
Query: 265 DGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPW 324
+ N + + ++MPK+ ++L N +CDCH ++S W+R + + C++P
Sbjct: 225 NNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLR--QRRTVGQFTLCMAPV 282
Query: 325 YLEG 328
+L G
Sbjct: 283 HLRG 286
Score = 85.4 bits (202), Expect = 2e-15
Identities = 85/404 (21%), Positives = 171/404 (42%), Gaps = 22/404 (5%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
++ N + + G+F+ LV+L+ L L N + + F + L + L +N L T+ +
Sbjct: 398 LYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKG 457
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKL 120
LFA ++T+ ++ N V +L Y LQ + + + + K + +K
Sbjct: 458 LFAPLQSIQTLHLAQNPFVCDCHLKWLADY-LQDNPIETSGARCSSPRRLANKRISQIKS 516
Query: 121 -------SDNKINNISDNAFENXX-------XXXXXXXDRNKLKNIPTQLFNNLKCLIFL 166
S++ + S F + KL IP+ L + L
Sbjct: 517 KKFRCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLN 576
Query: 167 DLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINI 226
D + +++ G+ F+ L LR ++L N + ++ + F ++++L L+ N+L ++
Sbjct: 577 D-NEVSVLEATGI-FKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHG 634
Query: 227 TAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIV 286
F G V F+ L ++ L L N ++ + L+ +
Sbjct: 635 RVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTI 694
Query: 287 KLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPEL-CAGQWA 345
L NP++C+CH ++ W+R + +I +P C P++L+ ++ + + C G
Sbjct: 695 NLLSNPFNCNCHLAWLGKWLR--KRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEE 752
Query: 346 SMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWPIPVSESILDTH 389
S LSPR P +Q + +V RC G+ P + + + + +
Sbjct: 753 SSCQLSPRCP-EQCTCME-TVVRCSNKGLRALPRGMPKDVTELY 794
Score = 80.2 bits (189), Expect = 7e-14
Identities = 47/136 (34%), Positives = 72/136 (52%), Gaps = 1/136 (0%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
LDL +N I I F+ LKNL++L L DN+++ I AF++ ++NKL+ +P
Sbjct: 102 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLP 161
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
LF + L LDLS N + + F + ++NL L N +S I D F +LE
Sbjct: 162 ELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEI 221
Query: 214 LDLSKNKLRFINITAF 229
L L+ N + I +T+F
Sbjct: 222 LTLNNNNISRILVTSF 237
Score = 79.0 bits (186), Expect = 2e-13
Identities = 43/123 (34%), Positives = 71/123 (57%), Gaps = 1/123 (0%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F L NL+ L L+ N + I+ AF K+L + L+ N L LPE LF + L +D+
Sbjct: 117 FAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDL 176
Query: 74 SNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNA 132
S N++ +P +F G+ ++ L L N I I++G F +L++L+IL L++N I+ I +
Sbjct: 177 SENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTS 236
Query: 133 FEN 135
F +
Sbjct: 237 FNH 239
Score = 74.5 bits (175), Expect = 4e-12
Identities = 40/124 (32%), Positives = 65/124 (52%), Gaps = 1/124 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN V + G F+ L L+ LRL +N L+ + F ST KL +DLS N + +P K F
Sbjct: 130 DNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAF 189
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
T ++ + + NN + + +F L L+IL L+ N I I +F+ + ++ L+L
Sbjct: 190 RGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLH 249
Query: 122 DNKI 125
N +
Sbjct: 250 SNHL 253
Score = 73.7 bits (173), Expect = 6e-12
Identities = 42/154 (27%), Positives = 76/154 (49%), Gaps = 1/154 (0%)
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINN 127
E +D+ N + + F GL +L++L L N++ I+ G F LK L+ L+L+ NK+
Sbjct: 100 ERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQV 159
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + F++ N+++ IP + F + + L L NN++ + F +L+ L
Sbjct: 160 LPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDL 219
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
L L N +S+I +F+ + L L N L
Sbjct: 220 EILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 253
Score = 73.3 bits (172), Expect = 8e-12
Identities = 43/126 (34%), Positives = 69/126 (54%), Gaps = 4/126 (3%)
Query: 9 LPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFL 68
+P + E +V + RL++N ++ I + AFT KKL +D+S N + + F L
Sbjct: 337 IPANLPEGIVEI---RLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSL 393
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINN 127
++ + N++ + F GL SLQ+L L+ NKI ++ TF L+NL +L L DNK+
Sbjct: 394 TSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQT 453
Query: 128 ISDNAF 133
IS F
Sbjct: 454 ISKGLF 459
Score = 68.1 bits (159), Expect = 3e-10
Identities = 81/314 (25%), Positives = 136/314 (43%), Gaps = 41/314 (13%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N +E + G +F L LKTL L+ N + + ++ F + + L +N + T+ F
Sbjct: 627 NQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFT 686
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLS-- 121
L TI++ +N ++LG + + +S N Q F LK + I ++
Sbjct: 687 TLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNP--RCQK-PFFLKEIPIQDVAIQ 743
Query: 122 -------DNKINNISDNAFENXXXXXXXXXDRNK-LKNIPTQLFNNLKCLIFLDLSNNNL 173
+ +S E NK L+ +P + K + L L N+L
Sbjct: 744 DFTCDGNEESSCQLSPRCPEQCTCMETVVRCSNKGLRALPRGM---PKDVTELYLEGNHL 800
Query: 174 MSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXX 233
++ E +L+ L +DL N++S + + TFS+ +L L LS N+LR I
Sbjct: 801 TAVPR-ELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCI--------- 850
Query: 234 XXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPW 293
VH AF+ L++L L L GN S+P + + + L+ + L NP
Sbjct: 851 -------------PVH--AFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 895
Query: 294 HCDCHALYISAWVR 307
HCDC ++S WV+
Sbjct: 896 HCDCSLRWLSEWVK 909
Score = 62.1 bits (144), Expect = 2e-08
Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 1/156 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L RN + I F K L + L +N + + F + LE + ++ N++
Sbjct: 98 NAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKL 157
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXX 137
+P F L LDLS+N+IQ I F + +++ L+L +N I+ I D AF
Sbjct: 158 QVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALR 217
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ N + I FN++ + L L +N+L
Sbjct: 218 DLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 253
Score = 61.7 bits (143), Expect = 3e-08
Identities = 34/121 (28%), Positives = 64/121 (52%), Gaps = 1/121 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ +P G F LK + + +N + +I +AF K L + L N + + + LF
Sbjct: 353 NSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFD 412
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L+ + ++ N++ + ++F L +L +L L NK+Q I G F+ L+++Q L L+
Sbjct: 413 GLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQ 472
Query: 123 N 123
N
Sbjct: 473 N 473
Score = 56.4 bits (130), Expect = 1e-06
Identities = 40/181 (22%), Positives = 77/181 (42%), Gaps = 3/181 (1%)
Query: 163 LIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
++ + L N++ ++ F K L+ +D+ +N +S I + F +L L L NK+
Sbjct: 345 IVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKIT 404
Query: 223 FINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPK 282
I F G + F L+NL L L N ++ +
Sbjct: 405 EIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQS 464
Query: 283 LTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPEL-CA 341
+ + L+ NP+ CDCH +++ +++ N ++ C SP L + ++K + C+
Sbjct: 465 IQTLHLAQNPFVCDCHLKWLADYLQDNPIE--TSGARCSSPRRLANKRISQIKSKKFRCS 522
Query: 342 G 342
G
Sbjct: 523 G 523
Score = 56.0 bits (129), Expect = 1e-06
Identities = 40/150 (26%), Positives = 74/150 (49%), Gaps = 4/150 (2%)
Query: 71 IDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS 129
+D ++ +P++ G+ ++ L +N I+ I G F+ K L+ + +S N+I++I+
Sbjct: 327 VDCRGKGLMEIPANLPEGIVEIR---LEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIA 383
Query: 130 DNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRN 189
+AF+ NK+ I LF+ L L L L+ N + L F+ L+ L
Sbjct: 384 PDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNL 443
Query: 190 LDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
L L +N L I F+ +++ L L++N
Sbjct: 444 LSLYDNKLQTISKGLFAPLQSIQTLHLAQN 473
Score = 52.0 bits (119), Expect = 2e-05
Identities = 34/108 (31%), Positives = 49/108 (45%)
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
++L N I I AF +N++ +I F LK L L L N + +A
Sbjct: 348 IRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIA 407
Query: 178 GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
F+ L L+ L L N ++ + NTF D NL L L NKL+ I+
Sbjct: 408 KGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTIS 455
>AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein.
Length = 1525
Score = 87.0 bits (206), Expect = 6e-16
Identities = 57/198 (28%), Positives = 93/198 (46%), Gaps = 3/198 (1%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N + I F L+ L L L N + ++ F+ LK L L L N L P+ F
Sbjct: 65 NNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFL 124
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
L +LDLS+N+++ I AF G + AF L++L L L+
Sbjct: 125 GTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNN 184
Query: 267 NMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYL 326
N L + ++MPKL +L N +CDCH ++S W+R ++ Y+ C+ P +L
Sbjct: 185 NNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLR-KRPRVGLYT-QCMGPSHL 242
Query: 327 EGHFLKKLKFPE-LCAGQ 343
GH + +++ E +C+ +
Sbjct: 243 RGHNVAEVQKREFVCSDE 260
Score = 77.0 bits (181), Expect = 7e-13
Identities = 41/133 (30%), Positives = 74/133 (55%), Gaps = 1/133 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ + F L +L+ L+L N + I+ AF K+L + L+ N+L PE LF
Sbjct: 65 NNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFL 124
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+S N++ +P +F G ++ L L N+I I++G F +L++L++L L++
Sbjct: 125 GTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNN 184
Query: 123 NKINNISDNAFEN 135
N I +S +F +
Sbjct: 185 NNITRLSVASFNH 197
Score = 74.1 bits (174), Expect = 5e-12
Identities = 41/112 (36%), Positives = 63/112 (56%), Gaps = 1/112 (0%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
+RL++N ++ I AF+ KKL +DLSNN + L F L ++ + N++ +P
Sbjct: 309 IRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELP 368
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAF 133
F GL+SLQ+L L+ NKI ++ F L NL +L L DNK+ I+ F
Sbjct: 369 KSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTF 420
Score = 72.5 bits (170), Expect = 1e-11
Identities = 44/136 (32%), Positives = 70/136 (51%), Gaps = 1/136 (0%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
LDL+ N I I F+ L++L++L+L +NKI+ I AF++ +RN L+ P
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
LF L LDLS N + ++ F ++NL L N +S I D F +LE
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 214 LDLSKNKLRFINITAF 229
L L+ N + +++ +F
Sbjct: 180 LTLNNNNITRLSVASF 195
Score = 72.5 bits (170), Expect = 1e-11
Identities = 85/426 (19%), Positives = 169/426 (39%), Gaps = 25/426 (5%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
++ N + LP +FE L +L+ L L N + + +AF L + L +N L T+ +
Sbjct: 359 LYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKG 418
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLY-------SLQILDLSKNKIQNIQNGTFSLK 113
F+ ++T+ ++ N + +L Y + S ++ N + G K
Sbjct: 419 TFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPIETSGARCTSPRRLANKRIGQIKSK 478
Query: 114 NLQILKLSDNKINNISDNAFENXX-------XXXXXXXDRNKLKNIPTQLFNNLKCLIFL 166
+ D + + +S + F + KL IP + + L
Sbjct: 479 KFRCSGTEDYR-SKLSGDCFADLACPEKCRCEGTTVDCSNQKLNKIPEHI---PQYTAEL 534
Query: 167 DLSNNNLMSLAGVE-FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
L+NN L F+ L LR ++ N ++ I + F + ++ L+ N+L +
Sbjct: 535 RLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQ 594
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
F G V +F L ++ L L N ++ D + L+
Sbjct: 595 HKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLST 654
Query: 286 VKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPELCAGQWA 345
+ L NP++C+C+ ++ W+R + +I +P C P++L+ ++ + +
Sbjct: 655 LNLLANPFNCNCYLAWLGEWLR--KKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCDDGN 712
Query: 346 SMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWP--IP--VSESILDTHTGYVLDRGTTDI 401
+ SP +V RC G+ + P IP V+E LD + ++ + ++
Sbjct: 713 DDNSCSPLSRCPTECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPKELSNY 772
Query: 402 EDITTI 407
+ +T I
Sbjct: 773 KHLTLI 778
Score = 70.9 bits (166), Expect = 4e-11
Identities = 34/126 (26%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N + + G F+ L L+ LRL RN+L+ F T KL+ +DLS N + +P K
Sbjct: 86 LMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRK 145
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
F ++ + + N++ + +F L L++L L+ N I + +F+ + L+ +
Sbjct: 146 AFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFR 205
Query: 120 LSDNKI 125
L N +
Sbjct: 206 LHSNNL 211
Score = 67.7 bits (158), Expect = 4e-10
Identities = 37/121 (30%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ +P G F L+ + L N + E+ +AF + L + L N + LP+ LF
Sbjct: 314 NTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFE 373
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L+ + ++ N++ + D+F L++L +L L NK+Q I GTFS L+ +Q + L+
Sbjct: 374 GLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQ 433
Query: 123 N 123
N
Sbjct: 434 N 434
Score = 66.9 bits (156), Expect = 7e-10
Identities = 52/199 (26%), Positives = 91/199 (45%), Gaps = 27/199 (13%)
Query: 145 DRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNT 204
++N +K IP F+ K L +DLSNN + LA F+ L+ L +L L N ++++P +
Sbjct: 312 EQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSL 371
Query: 205 FSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYL 264
F F+L+ L L+ NK+ + + AF L NL L L
Sbjct: 372 FEGLFSLQLLLLNANKINCLRVDAFQD------------------------LHNLNLLSL 407
Query: 265 DGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPW 324
N ++ T + + + L+ NP+ CDCH +++ ++ N ++ C SP
Sbjct: 408 YDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPIE--TSGARCTSPR 465
Query: 325 YLEGHFLKKLKFPEL-CAG 342
L + ++K + C+G
Sbjct: 466 RLANKRIGQIKSKKFRCSG 484
Score = 61.3 bits (142), Expect = 4e-08
Identities = 44/156 (28%), Positives = 69/156 (44%), Gaps = 1/156 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L N + I F + L + L N + T+ F + LE + ++ N +
Sbjct: 56 NTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHL 115
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXX 137
P FLG L LDLS+N+IQ I F +++ L+L N+I+ I D AF
Sbjct: 116 QLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALR 175
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ N + + FN++ L L +NNL
Sbjct: 176 DLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 58.8 bits (136), Expect = 2e-07
Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 1/152 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+DL+ N + + + FA L + + N++ + +F L L+ L L++N +Q
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 107 NGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
F L L LS+N+I I AF D N++ I F L+ L
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
L L+NNN+ L+ F + LR L N L
Sbjct: 180 LTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 58.4 bits (135), Expect = 3e-07
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 1/124 (0%)
Query: 97 LSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQ 155
L +N I+ I G FS K L+ + LS+N+I+ ++ +AF+ NK+ +P
Sbjct: 311 LEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKS 370
Query: 156 LFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLD 215
LF L L L L+ N + L F+ L L L L +N L I TFS ++ +
Sbjct: 371 LFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMH 430
Query: 216 LSKN 219
L++N
Sbjct: 431 LAQN 434
Score = 54.8 bits (126), Expect = 3e-06
Identities = 41/121 (33%), Positives = 62/121 (51%), Gaps = 5/121 (4%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
++ LP GI + L L N + E ++ K L +DLSNN + TL + F+N
Sbjct: 741 LKVLPKGIPRDVTELY---LDGNQFTLVPKE-LSNYKHLTLIDLSNNRISTLSNQSFSNM 796
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNK 124
T L T+ +S NR+ +P +F GL SL++L L N I + G F+ L L L + N
Sbjct: 797 TQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANP 856
Query: 125 I 125
+
Sbjct: 857 L 857
Score = 53.6 bits (123), Expect = 7e-06
Identities = 67/318 (21%), Positives = 126/318 (39%), Gaps = 22/318 (6%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + + G FE + + L N LE + + F + L + L +N + + F
Sbjct: 563 NNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSF 622
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI----------QNIQNGTFSL 112
+ + + + +N++ V +F L+SL L+L N + ++
Sbjct: 623 IGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRIVT 682
Query: 113 KNLQILKLSDNKINNISDNAFENXXXXXXXXXDR-NKLKNIPTQLFNNLKCL-IFLDLSN 170
N + K K I D A ++ + + L PT+ CL + SN
Sbjct: 683 GNPRCQKPYFLKEIPIQDVAIQDFTCDDGNDDNSCSPLSRCPTEC----TCLDTVVRCSN 738
Query: 171 NNLMSLA-GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
L L G+ + +L L N + +P S+ +L +DLS N++ ++ +F
Sbjct: 739 KGLKVLPKGIPRDVTELY----LDGNQFTLVPKE-LSNYKHLTLIDLSNNRISTLSNQSF 793
Query: 230 YGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLS 289
+ + F LK+L L L GN +P + + L+ + +
Sbjct: 794 SNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIG 853
Query: 290 GNPWHCDCHALYISAWVR 307
NP +CDC+ ++S WV+
Sbjct: 854 ANPLYCDCNMQWLSDWVK 871
Score = 43.6 bits (98), Expect = 0.008
Identities = 31/107 (28%), Positives = 44/107 (41%)
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
++L N I I AF N++ + F L+ L L L N + L
Sbjct: 309 IRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELP 368
Query: 178 GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
FE L L+ L L N ++ + + F D NL L L NKL+ I
Sbjct: 369 KSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTI 415
>AL356953-4|CAI15930.1| 828|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 828
Score = 85.8 bits (203), Expect = 1e-15
Identities = 66/228 (28%), Positives = 103/228 (45%), Gaps = 7/228 (3%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ ++PG F L +LK L LQ N L I +EA L +DL+ N L P +
Sbjct: 57 NHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLDLNYNKLQEFPVAIRT 116
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L+ + NN + +P +F+G LQ + N IQ + F L L L L+
Sbjct: 117 LGR-LQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG 175
Query: 123 -NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
I D + R ++ +P+ + L L L+LS+N + L +
Sbjct: 176 AMDIQEFPD--LKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSL-- 231
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
+ L + L+ N + +I +TFS +L+ LDLS N +R I+ AF
Sbjct: 232 HRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAF 279
Score = 76.2 bits (179), Expect = 1e-12
Identities = 80/292 (27%), Positives = 123/292 (42%), Gaps = 14/292 (4%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ L G+F L L+ LRL N+L I +AF+ L + L NN L +P +
Sbjct: 33 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 92
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L+++D++ N++ P + L LQ L N I+ I F LQ + D
Sbjct: 93 ELPSLQSLDLNYNKLQEFPV-AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYD 151
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLK---CLIFLDLSNNNLMSLAGV 179
N I + +AF+ N +I Q F +LK L L L+ + L
Sbjct: 152 NPIQFVGRSAFQ--YLPKLHTLSLNGAMDI--QEFPDLKGTTSLEILTLTRAGIRLLPSG 207
Query: 180 EFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXX 239
+ L LR L+L N + ++P + C LE++ L N++ I F
Sbjct: 208 MCQQLPRLRVLELSHNQIEELP--SLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALD 265
Query: 240 XXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+H +AFS L +L L L N +LP L + L +KL GN
Sbjct: 266 LSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP---LAGLGGLMHLKLKGN 314
Score = 64.5 bits (150), Expect = 4e-09
Identities = 52/179 (29%), Positives = 80/179 (44%), Gaps = 5/179 (2%)
Query: 48 DLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI-Q 106
DLS N L L LF + FLE + +S N + ++P +F GLYSL+IL L N++ I
Sbjct: 29 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 88
Query: 107 NGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFL 166
+ L +LQ L L+ NK+ A N +K IP + F L +
Sbjct: 89 EALWELPSLQSLDLNYNKLQEF-PVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTI 147
Query: 167 DLSNNNLMSLAGVEFESLKLLRNLDLK-ENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+N + + F+ L L L L + + PD +LE L L++ +R +
Sbjct: 148 HFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPD--LKGTTSLEILTLTRAGIRLL 204
Score = 44.4 bits (100), Expect = 0.004
Identities = 37/126 (29%), Positives = 47/126 (37%), Gaps = 1/126 (0%)
Query: 167 DLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINI 226
DLS NNL L F L+ L L L N LS IP FS ++L+ L L N+L I
Sbjct: 29 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 88
Query: 227 TAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIV 286
A + E A L L L N ++P + P L +
Sbjct: 89 EALWELPSLQSLDLNYNKLQEFPV-AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTI 147
Query: 287 KLSGNP 292
NP
Sbjct: 148 HFYDNP 153
>AF190501-1|AAG17168.1| 828|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 828
Score = 85.8 bits (203), Expect = 1e-15
Identities = 66/228 (28%), Positives = 103/228 (45%), Gaps = 7/228 (3%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ ++PG F L +LK L LQ N L I +EA L +DL+ N L P +
Sbjct: 57 NHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLDLNYNKLQEFPVAIRT 116
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L+ + NN + +P +F+G LQ + N IQ + F L L L L+
Sbjct: 117 LGR-LQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG 175
Query: 123 -NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
I D + R ++ +P+ + L L L+LS+N + L +
Sbjct: 176 AMDIQEFPD--LKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSL-- 231
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
+ L + L+ N + +I +TFS +L+ LDLS N +R I+ AF
Sbjct: 232 HRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAF 279
Score = 76.2 bits (179), Expect = 1e-12
Identities = 80/292 (27%), Positives = 123/292 (42%), Gaps = 14/292 (4%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ L G+F L L+ LRL N+L I +AF+ L + L NN L +P +
Sbjct: 33 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 92
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L+++D++ N++ P + L LQ L N I+ I F LQ + D
Sbjct: 93 ELPSLQSLDLNYNKLQEFPV-AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYD 151
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLK---CLIFLDLSNNNLMSLAGV 179
N I + +AF+ N +I Q F +LK L L L+ + L
Sbjct: 152 NPIQFVGRSAFQ--YLPKLHTLSLNGAMDI--QEFPDLKGTTSLEILTLTRAGIRLLPSG 207
Query: 180 EFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXX 239
+ L LR L+L N + ++P + C LE++ L N++ I F
Sbjct: 208 MCQQLPRLRVLELSHNQIEELP--SLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALD 265
Query: 240 XXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+H +AFS L +L L L N +LP L + L +KL GN
Sbjct: 266 LSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP---LAGLGGLMHLKLKGN 314
Score = 64.5 bits (150), Expect = 4e-09
Identities = 52/179 (29%), Positives = 80/179 (44%), Gaps = 5/179 (2%)
Query: 48 DLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI-Q 106
DLS N L L LF + FLE + +S N + ++P +F GLYSL+IL L N++ I
Sbjct: 29 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 88
Query: 107 NGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFL 166
+ L +LQ L L+ NK+ A N +K IP + F L +
Sbjct: 89 EALWELPSLQSLDLNYNKLQEF-PVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTI 147
Query: 167 DLSNNNLMSLAGVEFESLKLLRNLDLK-ENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+N + + F+ L L L L + + PD +LE L L++ +R +
Sbjct: 148 HFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPD--LKGTTSLEILTLTRAGIRLL 204
Score = 44.4 bits (100), Expect = 0.004
Identities = 37/126 (29%), Positives = 47/126 (37%), Gaps = 1/126 (0%)
Query: 167 DLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINI 226
DLS NNL L F L+ L L L N LS IP FS ++L+ L L N+L I
Sbjct: 29 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 88
Query: 227 TAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIV 286
A + E A L L L N ++P + P L +
Sbjct: 89 EALWELPSLQSLDLNYNKLQEFPV-AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTI 147
Query: 287 KLSGNP 292
NP
Sbjct: 148 HFYDNP 153
>BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein 1 protein.
Length = 347
Score = 85.4 bits (202), Expect = 2e-15
Identities = 67/261 (25%), Positives = 108/261 (41%), Gaps = 7/261 (2%)
Query: 78 VVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENX 136
+ ++P++ G LQ L LS N ++++ + L++L L+ N + + F+
Sbjct: 80 LTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQAS 139
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
N+L+ + + LK L LDLS N L L + LLR LDL EN
Sbjct: 140 ATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQ 199
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSML 256
L +P + LE+L L NKL+ + V AF L
Sbjct: 200 LETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGL 259
Query: 257 KNLTTLYLDGNMFPSLPSRTLDYM--PKLTI---VKLSGNPWHCDCHALYISAWVRLNEM 311
+ L L L N S+P + P + +SGNPW CD + + W++ +
Sbjct: 260 RQLDMLDLSNNSLASVPEGLWASLGQPNWDMRDGFDISGNPWICDQNLSDLYRWLQAQKD 319
Query: 312 KIWDYSPT-CVSPWYLEGHFL 331
K++ + T C P ++G L
Sbjct: 320 KMFSQNDTRCAGPEAVKGQTL 340
Score = 83.8 bits (198), Expect = 6e-15
Identities = 51/158 (32%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + LP G+F++ L TL L+ N LE ++ K L H+DLS N L LP L A
Sbjct: 126 NALTGLPSGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLA 185
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI-QNGTFSLKNLQILKLSD 122
N T L T+D+ N++ +P D G L+ L L NK+Q + ++ +L+ L L+
Sbjct: 186 NFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNG 245
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNL 160
NK+ ++ AF+ N L ++P L+ +L
Sbjct: 246 NKLARVAAGAFQGLRQLDMLDLSNNSLASVPEGLWASL 283
Score = 80.6 bits (190), Expect = 6e-14
Identities = 53/203 (26%), Positives = 96/203 (47%), Gaps = 1/203 (0%)
Query: 5 HVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFAN 64
++ +LP + + L+ L L N LE + E +L +DL+ N L LP LF
Sbjct: 79 NLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQA 138
Query: 65 NTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDN 123
+ L+T+ + N++ + GL +L LDLS N+++ + G + L+ L L +N
Sbjct: 139 SATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGEN 198
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFES 183
++ + + + NKL+ + L L +L L+ N L +A F+
Sbjct: 199 QLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQG 258
Query: 184 LKLLRNLDLKENALSQIPDNTFS 206
L+ L LDL N+L+ +P+ ++
Sbjct: 259 LRQLDMLDLSNNSLASVPEGLWA 281
Score = 56.0 bits (129), Expect = 1e-06
Identities = 46/174 (26%), Positives = 72/174 (41%), Gaps = 1/174 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N +E L + L+ L L RN L + S F ++ L + L N L L
Sbjct: 102 NGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATLDTLVLKENQLEVLEVSWLH 161
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+S NR+ +P L+ LDL +N+++ + L+ L L
Sbjct: 162 GLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEG 221
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSL 176
NK+ + + + NKL + F L+ L LDLSNN+L S+
Sbjct: 222 NKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASV 275
Score = 50.8 bits (116), Expect = 5e-05
Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 1/129 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N +E L L L L L N L ++ + L +DL N L TLP L
Sbjct: 149 ENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLL 208
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
LE + + N++ + D L L+ L L+ NK+ + G F L+ L +L LS
Sbjct: 209 RGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLS 268
Query: 122 DNKINNISD 130
+N + ++ +
Sbjct: 269 NNSLASVPE 277
Score = 37.5 bits (83), Expect = 0.51
Identities = 22/87 (25%), Positives = 40/87 (45%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N +E LP + + L+ L L+ N L+ + + L ++ L+ N L + F
Sbjct: 197 ENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAF 256
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGL 89
L+ +D+SNN + VP + L
Sbjct: 257 QGLRQLDMLDLSNNSLASVPEGLWASL 283
>AY029183-1|AAK31796.1| 798|Homo sapiens SLIT1 isoform B protein.
Length = 798
Score = 85.4 bits (202), Expect = 2e-15
Identities = 45/133 (33%), Positives = 74/133 (55%), Gaps = 1/133 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ + F L L+ L+L N + ++ AF K+L + L+ N L+ LPE LF
Sbjct: 54 NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQ 113
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
NN L +D+S N + +P +F G L+ L L KN+I I+ G F +L+ L++L L++
Sbjct: 114 NNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNN 173
Query: 123 NKINNISDNAFEN 135
N I I ++F +
Sbjct: 174 NNITTIPVSSFNH 186
Score = 84.6 bits (200), Expect = 3e-15
Identities = 57/198 (28%), Positives = 88/198 (44%), Gaps = 3/198 (1%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N + I F LK L L L N + ++ F+ +K L L L N L +P+ F
Sbjct: 54 NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQ 113
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
+ L +LDLS+N ++ I AF G + AF L+ L L L+
Sbjct: 114 NNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNN 173
Query: 267 NMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYL 326
N ++P + ++MPKL +L N CDCH ++S W+R + C P L
Sbjct: 174 NNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLR--QRPTIGLFTQCSGPASL 231
Query: 327 EGHFLKKLKFPEL-CAGQ 343
G + +++ E C+GQ
Sbjct: 232 RGLNVAEVQKSEFSCSGQ 249
Score = 78.6 bits (185), Expect = 2e-13
Identities = 54/225 (24%), Positives = 99/225 (44%), Gaps = 3/225 (1%)
Query: 166 LDLSNNNLMSLAGVE-FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L L+NN + L F+ L L+ ++L N +S+I D F ++ +L L+ N+L I
Sbjct: 538 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 597
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
F G +H +F+ L+N+ L L N ++ D + L+
Sbjct: 598 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 657
Query: 285 IVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPELCAGQW 344
+ L NP++C+C ++ W+R + KI +P C +P +L L+ + FP+ +
Sbjct: 658 TLNLLANPFNCNCQLAWLGGWLR--KRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEG 715
Query: 345 ASMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWPIPVSESILDTH 389
PR Q A +V RC + P + +++ + +
Sbjct: 716 QEEGGCLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKNVTELY 760
Score = 75.4 bits (177), Expect = 2e-12
Identities = 44/136 (32%), Positives = 71/136 (52%), Gaps = 1/136 (0%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
L+L+ N I I F+ LK L++L+L +N+I + AF++ +RN+L +P
Sbjct: 49 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 108
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
LF N + L LDLS N + ++ F L+NL L +N +S I + F LE
Sbjct: 109 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 168
Query: 214 LDLSKNKLRFINITAF 229
L L+ N + I +++F
Sbjct: 169 LTLNNNNITTIPVSSF 184
Score = 68.9 bits (161), Expect = 2e-10
Identities = 39/126 (30%), Positives = 67/126 (53%), Gaps = 2/126 (1%)
Query: 3 DNHVEYLPG-GIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKL 61
+N + L G+F+ L +LK + L N + EI+ AF + + L+ N L ++ +
Sbjct: 542 NNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGM 601
Query: 62 FANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKL 120
F L T+ + NNR+ + +DSF GL ++++L L N+I + G F +L++L L L
Sbjct: 602 FRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNL 661
Query: 121 SDNKIN 126
N N
Sbjct: 662 LANPFN 667
Score = 66.5 bits (155), Expect = 1e-09
Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 1/126 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N + + G F+ + L+ LRL RN L + F + + L +DLS N + +P K
Sbjct: 75 LMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRK 134
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
F T L+ + + N++ + +F L L++L L+ N I I +F+ + L+ +
Sbjct: 135 AFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFR 194
Query: 120 LSDNKI 125
L N +
Sbjct: 195 LHSNHL 200
Score = 60.5 bits (140), Expect = 6e-08
Identities = 43/156 (27%), Positives = 70/156 (44%), Gaps = 1/156 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L N + I F K+L + L N + + F + LE + ++ N++
Sbjct: 45 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 104
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXX 137
+P F +L LDLS+N IQ I F +L+ L+L N+I+ I + AF
Sbjct: 105 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 164
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ N + IP FN++ L L +N+L
Sbjct: 165 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 58.8 bits (136), Expect = 2e-07
Identities = 38/127 (29%), Positives = 63/127 (49%), Gaps = 2/127 (1%)
Query: 95 LDLSKNKIQNIQ-NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNI 152
L L+ N+I ++ G F L +L+ + LS+NK++ I D AFE N+L++I
Sbjct: 538 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 597
Query: 153 PTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLE 212
+ +F L L L L NN + + F L+ +R L L +N ++ + F +L
Sbjct: 598 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 657
Query: 213 KLDLSKN 219
L+L N
Sbjct: 658 TLNLLAN 664
Score = 57.6 bits (133), Expect = 4e-07
Identities = 39/131 (29%), Positives = 65/131 (49%), Gaps = 11/131 (8%)
Query: 4 NHVEYLPGGIFESLVNLKTLR----------LQRNYLEEIDSEAFTSTKKLFHVDLSNNY 53
N ++ +P G F L+ +R L N + EI +AF + L + L N
Sbjct: 302 NGIKSIPPGAFSPYRKLRRIRPLSFCSPCRDLSNNQIAEIAPDAFQGLRSLNSLVLYGNK 361
Query: 54 LYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SL 112
+ LP +F L+ + ++ N++ + D+F L +L +L L NKIQ++ GTF SL
Sbjct: 362 ITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSL 421
Query: 113 KNLQILKLSDN 123
+ +Q L L+ N
Sbjct: 422 RAIQTLHLAQN 432
Score = 54.0 bits (124), Expect = 6e-06
Identities = 39/152 (25%), Positives = 67/152 (44%), Gaps = 1/152 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L+ N + + + FA L + + N++ V +F + L+ L L++N++ +
Sbjct: 49 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 108
Query: 107 NGTFSLKN-LQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
F L L LS+N I I AF D+N++ I F L+ L
Sbjct: 109 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 168
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
L L+NNN+ ++ F + LR L N L
Sbjct: 169 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 52.0 bits (119), Expect = 2e-05
Identities = 44/169 (26%), Positives = 74/169 (43%), Gaps = 26/169 (15%)
Query: 167 DLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINI 226
DLSNN + +A F+ L+ L +L L N ++ +P F + L+ L L+ NK+ I
Sbjct: 332 DLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRP 391
Query: 227 TAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIV 286
A F L+NL+ L L N SL T + + +
Sbjct: 392 DA------------------------FQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTL 427
Query: 287 KLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLK 335
L+ NP+ CDC+ +++ ++R N ++ C SP L + ++K
Sbjct: 428 HLAQNPFICDCNLKWLADFLRTNPIE--TSGARCASPRRLANKRIGQIK 474
Score = 50.4 bits (115), Expect = 7e-05
Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 1/101 (0%)
Query: 96 DLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPT 154
DLS N+I I F L++L L L NKI ++ F + NK+ I
Sbjct: 332 DLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRP 391
Query: 155 QLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
F +L+ L L L +N + SLA F SL+ ++ L L +N
Sbjct: 392 DAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 432
Score = 45.6 bits (103), Expect = 0.002
Identities = 27/100 (27%), Positives = 49/100 (49%)
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
LS+N+I I+ +AF+ NK+ ++P +F L L L L+ N + +
Sbjct: 333 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 392
Query: 180 EFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
F+ L+ L L L +N + + TF+ ++ L L++N
Sbjct: 393 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 432
Score = 35.1 bits (77), Expect = 2.7
Identities = 24/76 (31%), Positives = 34/76 (44%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N++ I F L+ L L L N + L F L L+ L L N ++ I + F
Sbjct: 336 NQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQ 395
Query: 207 DCFNLEKLDLSKNKLR 222
D NL L L NK++
Sbjct: 396 DLQNLSLLSLYDNKIQ 411
>AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1534
Score = 85.4 bits (202), Expect = 2e-15
Identities = 45/133 (33%), Positives = 74/133 (55%), Gaps = 1/133 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ + F L L+ L+L N + ++ AF K+L + L+ N L+ LPE LF
Sbjct: 71 NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQ 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
NN L +D+S N + +P +F G L+ L L KN+I I+ G F +L+ L++L L++
Sbjct: 131 NNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNN 190
Query: 123 NKINNISDNAFEN 135
N I I ++F +
Sbjct: 191 NNITTIPVSSFNH 203
Score = 84.6 bits (200), Expect = 3e-15
Identities = 57/198 (28%), Positives = 88/198 (44%), Gaps = 3/198 (1%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N + I F LK L L L N + ++ F+ +K L L L N L +P+ F
Sbjct: 71 NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQ 130
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
+ L +LDLS+N ++ I AF G + AF L+ L L L+
Sbjct: 131 NNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNN 190
Query: 267 NMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYL 326
N ++P + ++MPKL +L N CDCH ++S W+R + C P L
Sbjct: 191 NNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLR--QRPTIGLFTQCSGPASL 248
Query: 327 EGHFLKKLKFPEL-CAGQ 343
G + +++ E C+GQ
Sbjct: 249 RGLNVAEVQKSEFSCSGQ 266
Score = 78.6 bits (185), Expect = 2e-13
Identities = 54/225 (24%), Positives = 99/225 (44%), Gaps = 3/225 (1%)
Query: 166 LDLSNNNLMSLAGVE-FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L L+NN + L F+ L L+ ++L N +S+I D F ++ +L L+ N+L I
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
F G +H +F+ L+N+ L L N ++ D + L+
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 285 IVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPELCAGQW 344
+ L NP++C+C ++ W+R + KI +P C +P +L L+ + FP+ +
Sbjct: 665 TLNLLANPFNCNCQLAWLGGWLR--KRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEG 722
Query: 345 ASMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWPIPVSESILDTH 389
PR Q A +V RC + P + +++ + +
Sbjct: 723 QEEGGCLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKNVTELY 767
Score = 75.4 bits (177), Expect = 2e-12
Identities = 44/136 (32%), Positives = 71/136 (52%), Gaps = 1/136 (0%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
L+L+ N I I F+ LK L++L+L +N+I + AF++ +RN+L +P
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
LF N + L LDLS N + ++ F L+NL L +N +S I + F LE
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 214 LDLSKNKLRFINITAF 229
L L+ N + I +++F
Sbjct: 186 LTLNNNNITTIPVSSF 201
Score = 73.3 bits (172), Expect = 8e-12
Identities = 80/348 (22%), Positives = 143/348 (41%), Gaps = 23/348 (6%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ +P F +LK L+L +N + I+ AF + + L + L+NN + T+P F
Sbjct: 142 ENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSF 201
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
+ L T + +N + D L S + + +G SL+ L + ++
Sbjct: 202 NHMPKLRTFRLHSNHLF---CDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQK 258
Query: 123 NKIN-------------NISDNAFENXXXXXXXXXD-RNK-LKNIPTQLFNNLKCLIFLD 167
++ + +S + D R K L IP L + I L+
Sbjct: 259 SEFSCSGQGEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMT-EIRLE 317
Query: 168 LSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINIT 227
L N + S+ F + LR +DL N +++I + F +L L L NK+ +
Sbjct: 318 L--NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRG 375
Query: 228 AFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVK 287
F G + AF L+NL+ L L N SL T + + +
Sbjct: 376 VFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLH 435
Query: 288 LSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLK 335
L+ NP+ CDC+ +++ ++R N ++ C SP L + ++K
Sbjct: 436 LAQNPFICDCNLKWLADFLRTNPIE--TSGARCASPRRLANKRIGQIK 481
Score = 68.9 bits (161), Expect = 2e-10
Identities = 39/126 (30%), Positives = 67/126 (53%), Gaps = 2/126 (1%)
Query: 3 DNHVEYLPG-GIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKL 61
+N + L G+F+ L +LK + L N + EI+ AF + + L+ N L ++ +
Sbjct: 549 NNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGM 608
Query: 62 FANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKL 120
F L T+ + NNR+ + +DSF GL ++++L L N+I + G F +L++L L L
Sbjct: 609 FRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNL 668
Query: 121 SDNKIN 126
N N
Sbjct: 669 LANPFN 674
Score = 66.5 bits (155), Expect = 1e-09
Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 1/126 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N + + G F+ + L+ LRL RN L + F + + L +DLS N + +P K
Sbjct: 92 LMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRK 151
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
F T L+ + + N++ + +F L L++L L+ N I I +F+ + L+ +
Sbjct: 152 AFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFR 211
Query: 120 LSDNKI 125
L N +
Sbjct: 212 LHSNHL 217
Score = 60.5 bits (140), Expect = 6e-08
Identities = 43/156 (27%), Positives = 70/156 (44%), Gaps = 1/156 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L N + I F K+L + L N + + F + LE + ++ N++
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXX 137
+P F +L LDLS+N IQ I F +L+ L+L N+I+ I + AF
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 181
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ N + IP FN++ L L +N+L
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 58.8 bits (136), Expect = 2e-07
Identities = 38/127 (29%), Positives = 63/127 (49%), Gaps = 2/127 (1%)
Query: 95 LDLSKNKIQNIQ-NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNI 152
L L+ N+I ++ G F L +L+ + LS+NK++ I D AFE N+L++I
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 153 PTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLE 212
+ +F L L L L NN + + F L+ +R L L +N ++ + F +L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 213 KLDLSKN 219
L+L N
Sbjct: 665 TLNLLAN 671
Score = 57.6 bits (133), Expect = 4e-07
Identities = 77/338 (22%), Positives = 137/338 (40%), Gaps = 42/338 (12%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N +E + G+F L L+TL L+ N + I +++FT + + + L +N + T+ F
Sbjct: 599 NQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFD 658
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLK-NLQILKLSD 122
L T+++ N ++LG + + ++ N QN F + LQ + D
Sbjct: 659 TLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNP--RCQNPDFLRQIPLQDVAFPD 716
Query: 123 NKINNISDNAF---------ENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ + E L+ +P + N+ L +LD N
Sbjct: 717 FRCEEGQEEGGCLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKNVTEL-YLD---GNQ 772
Query: 174 MSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXX 233
+L + + K L+ +DL N +S + +++F++ L L LS N L+ I AF G
Sbjct: 773 FTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQG-- 830
Query: 234 XXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPW 293
L++L L L GN +L + L+ + + NP
Sbjct: 831 ----------------------LRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Query: 294 HCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFL 331
+CDCH ++S+WV+ + C P +EG L
Sbjct: 869 YCDCHLRWLSSWVKTGYKE--PGIARCAGPQDMEGKLL 904
Score = 55.2 bits (127), Expect = 2e-06
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 5/124 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+ H+ LP GI + N+ L L N + + T K L VDLSNN + +L F
Sbjct: 749 NKHLRALPKGIPK---NVTELYLDGNQFTLVPGQLSTF-KYLQLVDLSNNKISSLSNSSF 804
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
N + L T+ +S N + +P +F GL SL++L L N I +Q G F+ + +L L +
Sbjct: 805 TNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIG 864
Query: 122 DNKI 125
N +
Sbjct: 865 ANPL 868
Score = 54.0 bits (124), Expect = 6e-06
Identities = 39/152 (25%), Positives = 67/152 (44%), Gaps = 1/152 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L+ N + + + FA L + + N++ V +F + L+ L L++N++ +
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 107 NGTFSLKN-LQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
F L L LS+N I I AF D+N++ I F L+ L
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
L L+NNN+ ++ F + LR L N L
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
>AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1461
Score = 85.4 bits (202), Expect = 2e-15
Identities = 45/133 (33%), Positives = 74/133 (55%), Gaps = 1/133 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ + F L L+ L+L N + ++ AF K+L + L+ N L+ LPE LF
Sbjct: 71 NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQ 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
NN L +D+S N + +P +F G L+ L L KN+I I+ G F +L+ L++L L++
Sbjct: 131 NNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNN 190
Query: 123 NKINNISDNAFEN 135
N I I ++F +
Sbjct: 191 NNITTIPVSSFNH 203
Score = 84.6 bits (200), Expect = 3e-15
Identities = 57/198 (28%), Positives = 88/198 (44%), Gaps = 3/198 (1%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N + I F LK L L L N + ++ F+ +K L L L N L +P+ F
Sbjct: 71 NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQ 130
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
+ L +LDLS+N ++ I AF G + AF L+ L L L+
Sbjct: 131 NNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNN 190
Query: 267 NMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYL 326
N ++P + ++MPKL +L N CDCH ++S W+R + C P L
Sbjct: 191 NNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLR--QRPTIGLFTQCSGPASL 248
Query: 327 EGHFLKKLKFPEL-CAGQ 343
G + +++ E C+GQ
Sbjct: 249 RGLNVAEVQKSEFSCSGQ 266
Score = 78.6 bits (185), Expect = 2e-13
Identities = 54/225 (24%), Positives = 99/225 (44%), Gaps = 3/225 (1%)
Query: 166 LDLSNNNLMSLAGVE-FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L L+NN + L F+ L L+ ++L N +S+I D F ++ +L L+ N+L I
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
F G +H +F+ L+N+ L L N ++ D + L+
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 285 IVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPELCAGQW 344
+ L NP++C+C ++ W+R + KI +P C +P +L L+ + FP+ +
Sbjct: 665 TLNLLANPFNCNCQLAWLGGWLR--KRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEG 722
Query: 345 ASMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWPIPVSESILDTH 389
PR Q A +V RC + P + +++ + +
Sbjct: 723 QEEGGCLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKNVTELY 767
Score = 75.4 bits (177), Expect = 2e-12
Identities = 44/136 (32%), Positives = 71/136 (52%), Gaps = 1/136 (0%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
L+L+ N I I F+ LK L++L+L +N+I + AF++ +RN+L +P
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
LF N + L LDLS N + ++ F L+NL L +N +S I + F LE
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 214 LDLSKNKLRFINITAF 229
L L+ N + I +++F
Sbjct: 186 LTLNNNNITTIPVSSF 201
Score = 73.3 bits (172), Expect = 8e-12
Identities = 80/348 (22%), Positives = 143/348 (41%), Gaps = 23/348 (6%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ +P F +LK L+L +N + I+ AF + + L + L+NN + T+P F
Sbjct: 142 ENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSF 201
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
+ L T + +N + D L S + + +G SL+ L + ++
Sbjct: 202 NHMPKLRTFRLHSNHLF---CDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQK 258
Query: 123 NKIN-------------NISDNAFENXXXXXXXXXD-RNK-LKNIPTQLFNNLKCLIFLD 167
++ + +S + D R K L IP L + I L+
Sbjct: 259 SEFSCSGQGEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMT-EIRLE 317
Query: 168 LSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINIT 227
L N + S+ F + LR +DL N +++I + F +L L L NK+ +
Sbjct: 318 L--NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRG 375
Query: 228 AFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVK 287
F G + AF L+NL+ L L N SL T + + +
Sbjct: 376 VFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLH 435
Query: 288 LSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLK 335
L+ NP+ CDC+ +++ ++R N ++ C SP L + ++K
Sbjct: 436 LAQNPFICDCNLKWLADFLRTNPIE--TSGARCASPRRLANKRIGQIK 481
Score = 68.9 bits (161), Expect = 2e-10
Identities = 39/126 (30%), Positives = 67/126 (53%), Gaps = 2/126 (1%)
Query: 3 DNHVEYLPG-GIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKL 61
+N + L G+F+ L +LK + L N + EI+ AF + + L+ N L ++ +
Sbjct: 549 NNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGM 608
Query: 62 FANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKL 120
F L T+ + NNR+ + +DSF GL ++++L L N+I + G F +L++L L L
Sbjct: 609 FRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNL 668
Query: 121 SDNKIN 126
N N
Sbjct: 669 LANPFN 674
Score = 66.5 bits (155), Expect = 1e-09
Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 1/126 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N + + G F+ + L+ LRL RN L + F + + L +DLS N + +P K
Sbjct: 92 LMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRK 151
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
F T L+ + + N++ + +F L L++L L+ N I I +F+ + L+ +
Sbjct: 152 AFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFR 211
Query: 120 LSDNKI 125
L N +
Sbjct: 212 LHSNHL 217
Score = 60.5 bits (140), Expect = 6e-08
Identities = 43/156 (27%), Positives = 70/156 (44%), Gaps = 1/156 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L N + I F K+L + L N + + F + LE + ++ N++
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXX 137
+P F +L LDLS+N IQ I F +L+ L+L N+I+ I + AF
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 181
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ N + IP FN++ L L +N+L
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 58.8 bits (136), Expect = 2e-07
Identities = 38/127 (29%), Positives = 63/127 (49%), Gaps = 2/127 (1%)
Query: 95 LDLSKNKIQNIQ-NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNI 152
L L+ N+I ++ G F L +L+ + LS+NK++ I D AFE N+L++I
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 153 PTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLE 212
+ +F L L L L NN + + F L+ +R L L +N ++ + F +L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 213 KLDLSKN 219
L+L N
Sbjct: 665 TLNLLAN 671
Score = 57.6 bits (133), Expect = 4e-07
Identities = 77/338 (22%), Positives = 137/338 (40%), Gaps = 42/338 (12%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N +E + G+F L L+TL L+ N + I +++FT + + + L +N + T+ F
Sbjct: 599 NQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFD 658
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLK-NLQILKLSD 122
L T+++ N ++LG + + ++ N QN F + LQ + D
Sbjct: 659 TLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNP--RCQNPDFLRQIPLQDVAFPD 716
Query: 123 NKINNISDNAF---------ENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ + E L+ +P + N+ L +LD N
Sbjct: 717 FRCEEGQEEGGCLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKNVTEL-YLD---GNQ 772
Query: 174 MSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXX 233
+L + + K L+ +DL N +S + +++F++ L L LS N L+ I AF G
Sbjct: 773 FTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQG-- 830
Query: 234 XXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPW 293
L++L L L GN +L + L+ + + NP
Sbjct: 831 ----------------------LRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Query: 294 HCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFL 331
+CDCH ++S+WV+ + C P +EG L
Sbjct: 869 YCDCHLRWLSSWVKTGYKE--PGIARCAGPQDMEGKLL 904
Score = 55.2 bits (127), Expect = 2e-06
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 5/124 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+ H+ LP GI + N+ L L N + + T K L VDLSNN + +L F
Sbjct: 749 NKHLRALPKGIPK---NVTELYLDGNQFTLVPGQLSTF-KYLQLVDLSNNKISSLSNSSF 804
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
N + L T+ +S N + +P +F GL SL++L L N I +Q G F+ + +L L +
Sbjct: 805 TNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIG 864
Query: 122 DNKI 125
N +
Sbjct: 865 ANPL 868
Score = 54.0 bits (124), Expect = 6e-06
Identities = 39/152 (25%), Positives = 67/152 (44%), Gaps = 1/152 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L+ N + + + FA L + + N++ V +F + L+ L L++N++ +
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 107 NGTFSLKN-LQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
F L L LS+N I I AF D+N++ I F L+ L
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
L L+NNN+ ++ F + LR L N L
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
>AL512424-3|CAI14257.1| 409|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 409
Score = 85.4 bits (202), Expect = 2e-15
Identities = 45/133 (33%), Positives = 74/133 (55%), Gaps = 1/133 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ + F L L+ L+L N + ++ AF K+L + L+ N L+ LPE LF
Sbjct: 71 NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQ 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
NN L +D+S N + +P +F G L+ L L KN+I I+ G F +L+ L++L L++
Sbjct: 131 NNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNN 190
Query: 123 NKINNISDNAFEN 135
N I I ++F +
Sbjct: 191 NNITTIPVSSFNH 203
Score = 84.6 bits (200), Expect = 3e-15
Identities = 57/198 (28%), Positives = 88/198 (44%), Gaps = 3/198 (1%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N + I F LK L L L N + ++ F+ +K L L L N L +P+ F
Sbjct: 71 NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQ 130
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
+ L +LDLS+N ++ I AF G + AF L+ L L L+
Sbjct: 131 NNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNN 190
Query: 267 NMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYL 326
N ++P + ++MPKL +L N CDCH ++S W+R + C P L
Sbjct: 191 NNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLR--QRPTIGLFTQCSGPASL 248
Query: 327 EGHFLKKLKFPEL-CAGQ 343
G + +++ E C+GQ
Sbjct: 249 RGLNVAEVQKSEFSCSGQ 266
Score = 75.4 bits (177), Expect = 2e-12
Identities = 44/136 (32%), Positives = 71/136 (52%), Gaps = 1/136 (0%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
L+L+ N I I F+ LK L++L+L +N+I + AF++ +RN+L +P
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
LF N + L LDLS N + ++ F L+NL L +N +S I + F LE
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 214 LDLSKNKLRFINITAF 229
L L+ N + I +++F
Sbjct: 186 LTLNNNNITTIPVSSF 201
Score = 66.5 bits (155), Expect = 1e-09
Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 1/126 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N + + G F+ + L+ LRL RN L + F + + L +DLS N + +P K
Sbjct: 92 LMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRK 151
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
F T L+ + + N++ + +F L L++L L+ N I I +F+ + L+ +
Sbjct: 152 AFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFR 211
Query: 120 LSDNKI 125
L N +
Sbjct: 212 LHSNHL 217
Score = 60.5 bits (140), Expect = 6e-08
Identities = 43/156 (27%), Positives = 70/156 (44%), Gaps = 1/156 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L N + I F K+L + L N + + F + LE + ++ N++
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXX 137
+P F +L LDLS+N IQ I F +L+ L+L N+I+ I + AF
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 181
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ N + IP FN++ L L +N+L
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 54.0 bits (124), Expect = 6e-06
Identities = 39/152 (25%), Positives = 67/152 (44%), Gaps = 1/152 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L+ N + + + FA L + + N++ V +F + L+ L L++N++ +
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 107 NGTFSLKN-LQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
F L L LS+N I I AF D+N++ I F L+ L
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
L L+NNN+ ++ F + LR L N L
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 33.5 bits (73), Expect = 8.3
Identities = 17/49 (34%), Positives = 27/49 (55%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQIL 95
+ L N + ++P F+ L ID+SNN++ + D+F GL SL L
Sbjct: 314 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSL 362
>AL512424-1|CAI14255.1| 782|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 782
Score = 85.4 bits (202), Expect = 2e-15
Identities = 45/133 (33%), Positives = 74/133 (55%), Gaps = 1/133 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ + F L L+ L+L N + ++ AF K+L + L+ N L+ LPE LF
Sbjct: 54 NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQ 113
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
NN L +D+S N + +P +F G L+ L L KN+I I+ G F +L+ L++L L++
Sbjct: 114 NNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNN 173
Query: 123 NKINNISDNAFEN 135
N I I ++F +
Sbjct: 174 NNITTIPVSSFNH 186
Score = 84.6 bits (200), Expect = 3e-15
Identities = 57/198 (28%), Positives = 88/198 (44%), Gaps = 3/198 (1%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N + I F LK L L L N + ++ F+ +K L L L N L +P+ F
Sbjct: 54 NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQ 113
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
+ L +LDLS+N ++ I AF G + AF L+ L L L+
Sbjct: 114 NNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNN 173
Query: 267 NMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYL 326
N ++P + ++MPKL +L N CDCH ++S W+R + C P L
Sbjct: 174 NNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLR--QRPTIGLFTQCSGPASL 231
Query: 327 EGHFLKKLKFPEL-CAGQ 343
G + +++ E C+GQ
Sbjct: 232 RGLNVAEVQKSEFSCSGQ 249
Score = 78.6 bits (185), Expect = 2e-13
Identities = 54/225 (24%), Positives = 99/225 (44%), Gaps = 3/225 (1%)
Query: 166 LDLSNNNLMSLAGVE-FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L L+NN + L F+ L L+ ++L N +S+I D F ++ +L L+ N+L I
Sbjct: 538 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 597
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
F G +H +F+ L+N+ L L N ++ D + L+
Sbjct: 598 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 657
Query: 285 IVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPELCAGQW 344
+ L NP++C+C ++ W+R + KI +P C +P +L L+ + FP+ +
Sbjct: 658 TLNLLANPFNCNCQLAWLGGWLR--KRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEG 715
Query: 345 ASMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWPIPVSESILDTH 389
PR Q A +V RC + P + +++ + +
Sbjct: 716 QEEGGCLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKNVTELY 760
Score = 75.4 bits (177), Expect = 2e-12
Identities = 44/136 (32%), Positives = 71/136 (52%), Gaps = 1/136 (0%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
L+L+ N I I F+ LK L++L+L +N+I + AF++ +RN+L +P
Sbjct: 49 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 108
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
LF N + L LDLS N + ++ F L+NL L +N +S I + F LE
Sbjct: 109 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 168
Query: 214 LDLSKNKLRFINITAF 229
L L+ N + I +++F
Sbjct: 169 LTLNNNNITTIPVSSF 184
Score = 68.9 bits (161), Expect = 2e-10
Identities = 39/126 (30%), Positives = 67/126 (53%), Gaps = 2/126 (1%)
Query: 3 DNHVEYLPG-GIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKL 61
+N + L G+F+ L +LK + L N + EI+ AF + + L+ N L ++ +
Sbjct: 542 NNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGM 601
Query: 62 FANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKL 120
F L T+ + NNR+ + +DSF GL ++++L L N+I + G F +L++L L L
Sbjct: 602 FRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNL 661
Query: 121 SDNKIN 126
N N
Sbjct: 662 LANPFN 667
Score = 66.5 bits (155), Expect = 1e-09
Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 1/126 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N + + G F+ + L+ LRL RN L + F + + L +DLS N + +P K
Sbjct: 75 LMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRK 134
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
F T L+ + + N++ + +F L L++L L+ N I I +F+ + L+ +
Sbjct: 135 AFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFR 194
Query: 120 LSDNKI 125
L N +
Sbjct: 195 LHSNHL 200
Score = 60.9 bits (141), Expect = 5e-08
Identities = 40/122 (32%), Positives = 64/122 (52%), Gaps = 11/122 (9%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHV----------DLSNNYLYTLPEKLFANNTFLETID 72
+RL+ N ++ I AF+ +KL + DLSNN + + F L ++
Sbjct: 297 IRLELNGIKSIPPGAFSPYRKLRRICPLSFCSPCRDLSNNQIAEIAPDAFQGLRSLNSLV 356
Query: 73 ISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDN 131
+ N++ +P F GLY+LQ+L L+ NKI I+ F L+NL +L L DNKI +++
Sbjct: 357 LYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKG 416
Query: 132 AF 133
F
Sbjct: 417 TF 418
Score = 60.5 bits (140), Expect = 6e-08
Identities = 43/156 (27%), Positives = 70/156 (44%), Gaps = 1/156 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L N + I F K+L + L N + + F + LE + ++ N++
Sbjct: 45 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 104
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXX 137
+P F +L LDLS+N IQ I F +L+ L+L N+I+ I + AF
Sbjct: 105 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 164
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ N + IP FN++ L L +N+L
Sbjct: 165 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 58.8 bits (136), Expect = 2e-07
Identities = 38/127 (29%), Positives = 63/127 (49%), Gaps = 2/127 (1%)
Query: 95 LDLSKNKIQNIQ-NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNI 152
L L+ N+I ++ G F L +L+ + LS+NK++ I D AFE N+L++I
Sbjct: 538 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 597
Query: 153 PTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLE 212
+ +F L L L L NN + + F L+ +R L L +N ++ + F +L
Sbjct: 598 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 657
Query: 213 KLDLSKN 219
L+L N
Sbjct: 658 TLNLLAN 664
Score = 56.8 bits (131), Expect = 8e-07
Identities = 33/100 (33%), Positives = 54/100 (54%), Gaps = 1/100 (1%)
Query: 25 LQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSD 84
L N + EI +AF + L + L N + LP +F L+ + ++ N++ + D
Sbjct: 333 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 392
Query: 85 SFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDN 123
+F L +L +L L NKIQ++ GTF SL+ +Q L L+ N
Sbjct: 393 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 432
Score = 54.0 bits (124), Expect = 6e-06
Identities = 39/152 (25%), Positives = 67/152 (44%), Gaps = 1/152 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L+ N + + + FA L + + N++ V +F + L+ L L++N++ +
Sbjct: 49 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 108
Query: 107 NGTFSLKN-LQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
F L L LS+N I I AF D+N++ I F L+ L
Sbjct: 109 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 168
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
L L+NNN+ ++ F + LR L N L
Sbjct: 169 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 52.0 bits (119), Expect = 2e-05
Identities = 44/169 (26%), Positives = 74/169 (43%), Gaps = 26/169 (15%)
Query: 167 DLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINI 226
DLSNN + +A F+ L+ L +L L N ++ +P F + L+ L L+ NK+ I
Sbjct: 332 DLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRP 391
Query: 227 TAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIV 286
A F L+NL+ L L N SL T + + +
Sbjct: 392 DA------------------------FQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTL 427
Query: 287 KLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLK 335
L+ NP+ CDC+ +++ ++R N ++ C SP L + ++K
Sbjct: 428 HLAQNPFICDCNLKWLADFLRTNPIE--TSGARCASPRRLANKRIGQIK 474
Score = 50.4 bits (115), Expect = 7e-05
Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 1/101 (0%)
Query: 96 DLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPT 154
DLS N+I I F L++L L L NKI ++ F + NK+ I
Sbjct: 332 DLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRP 391
Query: 155 QLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKEN 195
F +L+ L L L +N + SLA F SL+ ++ L L +N
Sbjct: 392 DAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 432
Score = 45.6 bits (103), Expect = 0.002
Identities = 27/100 (27%), Positives = 49/100 (49%)
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
LS+N+I I+ +AF+ NK+ ++P +F L L L L+ N + +
Sbjct: 333 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 392
Query: 180 EFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
F+ L+ L L L +N + + TF+ ++ L L++N
Sbjct: 393 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 432
Score = 35.1 bits (77), Expect = 2.7
Identities = 24/76 (31%), Positives = 34/76 (44%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N++ I F L+ L L L N + L F L L+ L L N ++ I + F
Sbjct: 336 NQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQ 395
Query: 207 DCFNLEKLDLSKNKLR 222
D NL L L NK++
Sbjct: 396 DLQNLSLLSLYDNKIQ 411
>AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1461
Score = 85.4 bits (202), Expect = 2e-15
Identities = 45/133 (33%), Positives = 74/133 (55%), Gaps = 1/133 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ + F L L+ L+L N + ++ AF K+L + L+ N L+ LPE LF
Sbjct: 71 NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQ 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
NN L +D+S N + +P +F G L+ L L KN+I I+ G F +L+ L++L L++
Sbjct: 131 NNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNN 190
Query: 123 NKINNISDNAFEN 135
N I I ++F +
Sbjct: 191 NNITTIPVSSFNH 203
Score = 84.6 bits (200), Expect = 3e-15
Identities = 57/198 (28%), Positives = 88/198 (44%), Gaps = 3/198 (1%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N + I F LK L L L N + ++ F+ +K L L L N L +P+ F
Sbjct: 71 NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQ 130
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
+ L +LDLS+N ++ I AF G + AF L+ L L L+
Sbjct: 131 NNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNN 190
Query: 267 NMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYL 326
N ++P + ++MPKL +L N CDCH ++S W+R + C P L
Sbjct: 191 NNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLR--QRPTIGLFTQCSGPASL 248
Query: 327 EGHFLKKLKFPEL-CAGQ 343
G + +++ E C+GQ
Sbjct: 249 RGLNVAEVQKSEFSCSGQ 266
Score = 78.6 bits (185), Expect = 2e-13
Identities = 54/225 (24%), Positives = 99/225 (44%), Gaps = 3/225 (1%)
Query: 166 LDLSNNNLMSLAGVE-FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L L+NN + L F+ L L+ ++L N +S+I D F ++ +L L+ N+L I
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
F G +H +F+ L+N+ L L N ++ D + L+
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 285 IVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPELCAGQW 344
+ L NP++C+C ++ W+R + KI +P C +P +L L+ + FP+ +
Sbjct: 665 TLNLLANPFNCNCQLAWLGGWLR--KRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEG 722
Query: 345 ASMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWPIPVSESILDTH 389
PR Q A +V RC + P + +++ + +
Sbjct: 723 QEEGGCLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKNVTELY 767
Score = 75.4 bits (177), Expect = 2e-12
Identities = 44/136 (32%), Positives = 71/136 (52%), Gaps = 1/136 (0%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
L+L+ N I I F+ LK L++L+L +N+I + AF++ +RN+L +P
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
LF N + L LDLS N + ++ F L+NL L +N +S I + F LE
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 214 LDLSKNKLRFINITAF 229
L L+ N + I +++F
Sbjct: 186 LTLNNNNITTIPVSSF 201
Score = 73.3 bits (172), Expect = 8e-12
Identities = 80/348 (22%), Positives = 143/348 (41%), Gaps = 23/348 (6%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ +P F +LK L+L +N + I+ AF + + L + L+NN + T+P F
Sbjct: 142 ENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSF 201
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
+ L T + +N + D L S + + +G SL+ L + ++
Sbjct: 202 NHMPKLRTFRLHSNHLF---CDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQK 258
Query: 123 NKIN-------------NISDNAFENXXXXXXXXXD-RNK-LKNIPTQLFNNLKCLIFLD 167
++ + +S + D R K L IP L + I L+
Sbjct: 259 SEFSCSGQGEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMT-EIRLE 317
Query: 168 LSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINIT 227
L N + S+ F + LR +DL N +++I + F +L L L NK+ +
Sbjct: 318 L--NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRG 375
Query: 228 AFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVK 287
F G + AF L+NL+ L L N SL T + + +
Sbjct: 376 VFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLH 435
Query: 288 LSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLK 335
L+ NP+ CDC+ +++ ++R N ++ C SP L + ++K
Sbjct: 436 LAQNPFICDCNLKWLADFLRTNPIE--TSGARCASPRRLANKRIGQIK 481
Score = 68.9 bits (161), Expect = 2e-10
Identities = 39/126 (30%), Positives = 67/126 (53%), Gaps = 2/126 (1%)
Query: 3 DNHVEYLPG-GIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKL 61
+N + L G+F+ L +LK + L N + EI+ AF + + L+ N L ++ +
Sbjct: 549 NNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGM 608
Query: 62 FANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKL 120
F L T+ + NNR+ + +DSF GL ++++L L N+I + G F +L++L L L
Sbjct: 609 FRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNL 668
Query: 121 SDNKIN 126
N N
Sbjct: 669 LANPFN 674
Score = 66.5 bits (155), Expect = 1e-09
Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 1/126 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N + + G F+ + L+ LRL RN L + F + + L +DLS N + +P K
Sbjct: 92 LMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRK 151
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
F T L+ + + N++ + +F L L++L L+ N I I +F+ + L+ +
Sbjct: 152 AFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFR 211
Query: 120 LSDNKI 125
L N +
Sbjct: 212 LHSNHL 217
Score = 60.5 bits (140), Expect = 6e-08
Identities = 43/156 (27%), Positives = 70/156 (44%), Gaps = 1/156 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L N + I F K+L + L N + + F + LE + ++ N++
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXX 137
+P F +L LDLS+N IQ I F +L+ L+L N+I+ I + AF
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 181
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ N + IP FN++ L L +N+L
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 58.8 bits (136), Expect = 2e-07
Identities = 38/127 (29%), Positives = 63/127 (49%), Gaps = 2/127 (1%)
Query: 95 LDLSKNKIQNIQ-NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNI 152
L L+ N+I ++ G F L +L+ + LS+NK++ I D AFE N+L++I
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 153 PTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLE 212
+ +F L L L L NN + + F L+ +R L L +N ++ + F +L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 213 KLDLSKN 219
L+L N
Sbjct: 665 TLNLLAN 671
Score = 57.6 bits (133), Expect = 4e-07
Identities = 77/338 (22%), Positives = 137/338 (40%), Gaps = 42/338 (12%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N +E + G+F L L+TL L+ N + I +++FT + + + L +N + T+ F
Sbjct: 599 NQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFD 658
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLK-NLQILKLSD 122
L T+++ N ++LG + + ++ N QN F + LQ + D
Sbjct: 659 TLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNP--RCQNPDFLRQIPLQDVAFPD 716
Query: 123 NKINNISDNAF---------ENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ + E L+ +P + N+ L +LD N
Sbjct: 717 FRCEEGQEEGGCLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKNVTEL-YLD---GNQ 772
Query: 174 MSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXX 233
+L + + K L+ +DL N +S + +++F++ L L LS N L+ I AF G
Sbjct: 773 FTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQG-- 830
Query: 234 XXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPW 293
L++L L L GN +L + L+ + + NP
Sbjct: 831 ----------------------LRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Query: 294 HCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFL 331
+CDCH ++S+WV+ + C P +EG L
Sbjct: 869 YCDCHLRWLSSWVKTGYKE--PGIARCAGPQDMEGKLL 904
Score = 55.2 bits (127), Expect = 2e-06
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 5/124 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+ H+ LP GI + N+ L L N + + T K L VDLSNN + +L F
Sbjct: 749 NKHLRALPKGIPK---NVTELYLDGNQFTLVPGQLSTF-KYLQLVDLSNNKISSLSNSSF 804
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
N + L T+ +S N + +P +F GL SL++L L N I +Q G F+ + +L L +
Sbjct: 805 TNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIG 864
Query: 122 DNKI 125
N +
Sbjct: 865 ANPL 868
Score = 54.0 bits (124), Expect = 6e-06
Identities = 39/152 (25%), Positives = 67/152 (44%), Gaps = 1/152 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L+ N + + + FA L + + N++ V +F + L+ L L++N++ +
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 107 NGTFSLKN-LQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
F L L LS+N I I AF D+N++ I F L+ L
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
L L+NNN+ ++ F + LR L N L
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
>AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1534
Score = 85.4 bits (202), Expect = 2e-15
Identities = 45/133 (33%), Positives = 74/133 (55%), Gaps = 1/133 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ + F L L+ L+L N + ++ AF K+L + L+ N L+ LPE LF
Sbjct: 71 NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQ 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
NN L +D+S N + +P +F G L+ L L KN+I I+ G F +L+ L++L L++
Sbjct: 131 NNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNN 190
Query: 123 NKINNISDNAFEN 135
N I I ++F +
Sbjct: 191 NNITTIPVSSFNH 203
Score = 84.6 bits (200), Expect = 3e-15
Identities = 57/198 (28%), Positives = 88/198 (44%), Gaps = 3/198 (1%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N + I F LK L L L N + ++ F+ +K L L L N L +P+ F
Sbjct: 71 NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQ 130
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
+ L +LDLS+N ++ I AF G + AF L+ L L L+
Sbjct: 131 NNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNN 190
Query: 267 NMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYL 326
N ++P + ++MPKL +L N CDCH ++S W+R + C P L
Sbjct: 191 NNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLR--QRPTIGLFTQCSGPASL 248
Query: 327 EGHFLKKLKFPEL-CAGQ 343
G + +++ E C+GQ
Sbjct: 249 RGLNVAEVQKSEFSCSGQ 266
Score = 78.6 bits (185), Expect = 2e-13
Identities = 54/225 (24%), Positives = 99/225 (44%), Gaps = 3/225 (1%)
Query: 166 LDLSNNNLMSLAGVE-FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L L+NN + L F+ L L+ ++L N +S+I D F ++ +L L+ N+L I
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
F G +H +F+ L+N+ L L N ++ D + L+
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 285 IVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPELCAGQW 344
+ L NP++C+C ++ W+R + KI +P C +P +L L+ + FP+ +
Sbjct: 665 TLNLLANPFNCNCQLAWLGGWLR--KRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEG 722
Query: 345 ASMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWPIPVSESILDTH 389
PR Q A +V RC + P + +++ + +
Sbjct: 723 QEEGGCLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKNVTELY 767
Score = 75.4 bits (177), Expect = 2e-12
Identities = 44/136 (32%), Positives = 71/136 (52%), Gaps = 1/136 (0%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
L+L+ N I I F+ LK L++L+L +N+I + AF++ +RN+L +P
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
LF N + L LDLS N + ++ F L+NL L +N +S I + F LE
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 214 LDLSKNKLRFINITAF 229
L L+ N + I +++F
Sbjct: 186 LTLNNNNITTIPVSSF 201
Score = 73.3 bits (172), Expect = 8e-12
Identities = 80/348 (22%), Positives = 143/348 (41%), Gaps = 23/348 (6%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ +P F +LK L+L +N + I+ AF + + L + L+NN + T+P F
Sbjct: 142 ENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSF 201
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
+ L T + +N + D L S + + +G SL+ L + ++
Sbjct: 202 NHMPKLRTFRLHSNHLF---CDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQK 258
Query: 123 NKIN-------------NISDNAFENXXXXXXXXXD-RNK-LKNIPTQLFNNLKCLIFLD 167
++ + +S + D R K L IP L + I L+
Sbjct: 259 SEFSCSGQGEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMT-EIRLE 317
Query: 168 LSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINIT 227
L N + S+ F + LR +DL N +++I + F +L L L NK+ +
Sbjct: 318 L--NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRG 375
Query: 228 AFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVK 287
F G + AF L+NL+ L L N SL T + + +
Sbjct: 376 VFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLH 435
Query: 288 LSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLK 335
L+ NP+ CDC+ +++ ++R N ++ C SP L + ++K
Sbjct: 436 LAQNPFICDCNLKWLADFLRTNPIE--TSGARCASPRRLANKRIGQIK 481
Score = 68.9 bits (161), Expect = 2e-10
Identities = 39/126 (30%), Positives = 67/126 (53%), Gaps = 2/126 (1%)
Query: 3 DNHVEYLPG-GIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKL 61
+N + L G+F+ L +LK + L N + EI+ AF + + L+ N L ++ +
Sbjct: 549 NNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGM 608
Query: 62 FANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKL 120
F L T+ + NNR+ + +DSF GL ++++L L N+I + G F +L++L L L
Sbjct: 609 FRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNL 668
Query: 121 SDNKIN 126
N N
Sbjct: 669 LANPFN 674
Score = 66.5 bits (155), Expect = 1e-09
Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 1/126 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N + + G F+ + L+ LRL RN L + F + + L +DLS N + +P K
Sbjct: 92 LMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRK 151
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
F T L+ + + N++ + +F L L++L L+ N I I +F+ + L+ +
Sbjct: 152 AFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFR 211
Query: 120 LSDNKI 125
L N +
Sbjct: 212 LHSNHL 217
Score = 60.5 bits (140), Expect = 6e-08
Identities = 43/156 (27%), Positives = 70/156 (44%), Gaps = 1/156 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L N + I F K+L + L N + + F + LE + ++ N++
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXX 137
+P F +L LDLS+N IQ I F +L+ L+L N+I+ I + AF
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 181
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ N + IP FN++ L L +N+L
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 58.8 bits (136), Expect = 2e-07
Identities = 38/127 (29%), Positives = 63/127 (49%), Gaps = 2/127 (1%)
Query: 95 LDLSKNKIQNIQ-NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNI 152
L L+ N+I ++ G F L +L+ + LS+NK++ I D AFE N+L++I
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 153 PTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLE 212
+ +F L L L L NN + + F L+ +R L L +N ++ + F +L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 213 KLDLSKN 219
L+L N
Sbjct: 665 TLNLLAN 671
Score = 57.6 bits (133), Expect = 4e-07
Identities = 77/338 (22%), Positives = 137/338 (40%), Gaps = 42/338 (12%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N +E + G+F L L+TL L+ N + I +++FT + + + L +N + T+ F
Sbjct: 599 NQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFD 658
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLK-NLQILKLSD 122
L T+++ N ++LG + + ++ N QN F + LQ + D
Sbjct: 659 TLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNP--RCQNPDFLRQIPLQDVAFPD 716
Query: 123 NKINNISDNAF---------ENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ + E L+ +P + N+ L +LD N
Sbjct: 717 FRCEEGQEEGGCLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKNVTEL-YLD---GNQ 772
Query: 174 MSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXX 233
+L + + K L+ +DL N +S + +++F++ L L LS N L+ I AF G
Sbjct: 773 FTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQG-- 830
Query: 234 XXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPW 293
L++L L L GN +L + L+ + + NP
Sbjct: 831 ----------------------LRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Query: 294 HCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFL 331
+CDCH ++S+WV+ + C P +EG L
Sbjct: 869 YCDCHLRWLSSWVKTGYKE--PGIARCAGPQDMEGKLL 904
Score = 55.2 bits (127), Expect = 2e-06
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 5/124 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+ H+ LP GI + N+ L L N + + T K L VDLSNN + +L F
Sbjct: 749 NKHLRALPKGIPK---NVTELYLDGNQFTLVPGQLSTF-KYLQLVDLSNNKISSLSNSSF 804
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
N + L T+ +S N + +P +F GL SL++L L N I +Q G F+ + +L L +
Sbjct: 805 TNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIG 864
Query: 122 DNKI 125
N +
Sbjct: 865 ANPL 868
Score = 54.0 bits (124), Expect = 6e-06
Identities = 39/152 (25%), Positives = 67/152 (44%), Gaps = 1/152 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L+ N + + + FA L + + N++ V +F + L+ L L++N++ +
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 107 NGTFSLKN-LQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
F L L LS+N I I AF D+N++ I F L+ L
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
L L+NNN+ ++ F + LR L N L
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
>AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein protein.
Length = 347
Score = 85.4 bits (202), Expect = 2e-15
Identities = 67/261 (25%), Positives = 108/261 (41%), Gaps = 7/261 (2%)
Query: 78 VVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENX 136
+ ++P++ G LQ L LS N ++++ + L++L L+ N + + F+
Sbjct: 80 LTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQAS 139
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
N+L+ + + LK L LDLS N L L + LLR LDL EN
Sbjct: 140 ATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQ 199
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSML 256
L +P + LE+L L NKL+ + V AF L
Sbjct: 200 LETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGL 259
Query: 257 KNLTTLYLDGNMFPSLPSRTLDYM--PKLTI---VKLSGNPWHCDCHALYISAWVRLNEM 311
+ L L L N S+P + P + +SGNPW CD + + W++ +
Sbjct: 260 RQLDMLDLSNNSLASVPEGLWASLGQPNWDMRDGFDISGNPWICDQNLSDLYRWLQAQKD 319
Query: 312 KIWDYSPT-CVSPWYLEGHFL 331
K++ + T C P ++G L
Sbjct: 320 KMFSQNDTRCAGPEAVKGQTL 340
Score = 83.8 bits (198), Expect = 6e-15
Identities = 51/158 (32%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + LP G+F++ L TL L+ N LE ++ K L H+DLS N L LP L A
Sbjct: 126 NALTGLPSGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLA 185
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI-QNGTFSLKNLQILKLSD 122
N T L T+D+ N++ +P D G L+ L L NK+Q + ++ +L+ L L+
Sbjct: 186 NFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNG 245
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNL 160
NK+ ++ AF+ N L ++P L+ +L
Sbjct: 246 NKLARVAAGAFQGLRQLDMLDLSNNSLASVPEGLWASL 283
Score = 80.6 bits (190), Expect = 6e-14
Identities = 53/203 (26%), Positives = 96/203 (47%), Gaps = 1/203 (0%)
Query: 5 HVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFAN 64
++ +LP + + L+ L L N LE + E +L +DL+ N L LP LF
Sbjct: 79 NLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQA 138
Query: 65 NTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDN 123
+ L+T+ + N++ + GL +L LDLS N+++ + G + L+ L L +N
Sbjct: 139 SATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGEN 198
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFES 183
++ + + + NKL+ + L L +L L+ N L +A F+
Sbjct: 199 QLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQG 258
Query: 184 LKLLRNLDLKENALSQIPDNTFS 206
L+ L LDL N+L+ +P+ ++
Sbjct: 259 LRQLDMLDLSNNSLASVPEGLWA 281
Score = 56.0 bits (129), Expect = 1e-06
Identities = 46/174 (26%), Positives = 72/174 (41%), Gaps = 1/174 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N +E L + L+ L L RN L + S F ++ L + L N L L
Sbjct: 102 NGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATLDTLVLKENQLEVLEVSWLH 161
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+S NR+ +P L+ LDL +N+++ + L+ L L
Sbjct: 162 GLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEG 221
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSL 176
NK+ + + + NKL + F L+ L LDLSNN+L S+
Sbjct: 222 NKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASV 275
Score = 50.8 bits (116), Expect = 5e-05
Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 1/129 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N +E L L L L L N L ++ + L +DL N L TLP L
Sbjct: 149 ENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLL 208
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
LE + + N++ + D L L+ L L+ NK+ + G F L+ L +L LS
Sbjct: 209 RGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLS 268
Query: 122 DNKINNISD 130
+N + ++ +
Sbjct: 269 NNSLASVPE 277
Score = 37.5 bits (83), Expect = 0.51
Identities = 22/87 (25%), Positives = 40/87 (45%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N +E LP + + L+ L L+ N L+ + + L ++ L+ N L + F
Sbjct: 197 ENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAF 256
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGL 89
L+ +D+SNN + VP + L
Sbjct: 257 QGLRQLDMLDLSNNSLASVPEGLWASL 283
>BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like
family peptide receptor 1 protein.
Length = 757
Score = 85.0 bits (201), Expect = 3e-15
Identities = 64/216 (29%), Positives = 98/216 (45%), Gaps = 24/216 (11%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + +L G+FE L L+ L ++ N+L I F L + L NN L LP+K
Sbjct: 184 NRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLC 243
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
++P L LDL N I N++N TF S NL +L +
Sbjct: 244 Q---------------HMPR--------LHWLDLEGNHIHNLRNLTFISCSNLTVLVMRK 280
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
NKIN++++N F NK++N+P +F +LK L L+LS N + + +F+
Sbjct: 281 NKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFD 340
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSK 218
L L++L L+ +S I F NL + K
Sbjct: 341 YLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIYFKK 376
Score = 83.8 bits (198), Expect = 6e-15
Identities = 61/231 (26%), Positives = 104/231 (45%), Gaps = 2/231 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N + LP F N L+ + + NN++ + +F GL SL L LS N+I ++
Sbjct: 131 MSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLK 190
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQ-LFNNLKCLI 164
G F L L+ L + DN ++ IS F N L +P + L ++ L
Sbjct: 191 PGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLH 250
Query: 165 FLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+LDL N++ +L + F S L L +++N ++ + +NTF+ L++LDL NK+ +
Sbjct: 251 WLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENL 310
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSR 275
F ++ F L L +L L+G ++ R
Sbjct: 311 PPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQR 361
Score = 71.7 bits (168), Expect = 3e-11
Identities = 57/247 (23%), Positives = 102/247 (41%), Gaps = 2/247 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N+ + LQ N + ++ + F + L + L NN + ++ F L + +S+NR+
Sbjct: 127 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 186
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAF-ENX 136
++ F L+ L+ L + N + I TF L +L +L L +N + + D ++
Sbjct: 187 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 246
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
+ N + N+ F + L L + N + L F L+ L LDL N
Sbjct: 247 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNK 306
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSML 256
+ +P F D L +L+LS N ++ I F + + F L
Sbjct: 307 IENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRMFRPL 366
Query: 257 KNLTTLY 263
NL+ +Y
Sbjct: 367 MNLSHIY 373
Score = 47.6 bits (108), Expect = 5e-04
Identities = 38/146 (26%), Positives = 57/146 (39%), Gaps = 1/146 (0%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N ++ +P F N L L L NN + S++ F L L L L N ++ + F
Sbjct: 136 NLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFE 195
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSM-LKNLTTLYLD 265
D LE L + N L I+ FYG + K + L L L+
Sbjct: 196 DLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLE 255
Query: 266 GNMFPSLPSRTLDYMPKLTIVKLSGN 291
GN +L + T LT++ + N
Sbjct: 256 GNHIHNLRNLTFISCSNLTVLVMRKN 281
Score = 45.2 bits (102), Expect = 0.003
Identities = 46/179 (25%), Positives = 66/179 (36%), Gaps = 1/179 (0%)
Query: 114 NLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
N+ + L N I + + F+N NK+ +I F L L L LS+N +
Sbjct: 127 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 186
Query: 174 MSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL-RFINITAFYGX 232
L FE L L L +++N LS+I TF +L L L N L R +
Sbjct: 187 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 246
Query: 233 XXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + F NLT L + N L T + KL + L N
Sbjct: 247 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSN 305
>BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 protein.
Length = 757
Score = 85.0 bits (201), Expect = 3e-15
Identities = 64/216 (29%), Positives = 98/216 (45%), Gaps = 24/216 (11%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + +L G+FE L L+ L ++ N+L I F L + L NN L LP+K
Sbjct: 184 NRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLC 243
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
++P L LDL N I N++N TF S NL +L +
Sbjct: 244 Q---------------HMPR--------LHWLDLEGNHIHNLRNLTFISCSNLTVLVMRK 280
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
NKIN++++N F NK++N+P +F +LK L L+LS N + + +F+
Sbjct: 281 NKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFD 340
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSK 218
L L++L L+ +S I F NL + K
Sbjct: 341 YLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIYFKK 376
Score = 83.8 bits (198), Expect = 6e-15
Identities = 61/231 (26%), Positives = 104/231 (45%), Gaps = 2/231 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N + LP F N L+ + + NN++ + +F GL SL L LS N+I ++
Sbjct: 131 MSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLK 190
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQ-LFNNLKCLI 164
G F L L+ L + DN ++ IS F N L +P + L ++ L
Sbjct: 191 PGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLH 250
Query: 165 FLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+LDL N++ +L + F S L L +++N ++ + +NTF+ L++LDL NK+ +
Sbjct: 251 WLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENL 310
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSR 275
F ++ F L L +L L+G ++ R
Sbjct: 311 PPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQR 361
Score = 71.7 bits (168), Expect = 3e-11
Identities = 57/247 (23%), Positives = 102/247 (41%), Gaps = 2/247 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N+ + LQ N + ++ + F + L + L NN + ++ F L + +S+NR+
Sbjct: 127 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 186
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAF-ENX 136
++ F L+ L+ L + N + I TF L +L +L L +N + + D ++
Sbjct: 187 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 246
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
+ N + N+ F + L L + N + L F L+ L LDL N
Sbjct: 247 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNK 306
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSML 256
+ +P F D L +L+LS N ++ I F + + F L
Sbjct: 307 IENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRMFRPL 366
Query: 257 KNLTTLY 263
NL+ +Y
Sbjct: 367 MNLSHIY 373
Score = 47.6 bits (108), Expect = 5e-04
Identities = 38/146 (26%), Positives = 57/146 (39%), Gaps = 1/146 (0%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N ++ +P F N L L L NN + S++ F L L L L N ++ + F
Sbjct: 136 NLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFE 195
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSM-LKNLTTLYLD 265
D LE L + N L I+ FYG + K + L L L+
Sbjct: 196 DLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLE 255
Query: 266 GNMFPSLPSRTLDYMPKLTIVKLSGN 291
GN +L + T LT++ + N
Sbjct: 256 GNHIHNLRNLTFISCSNLTVLVMRKN 281
Score = 45.2 bits (102), Expect = 0.003
Identities = 46/179 (25%), Positives = 66/179 (36%), Gaps = 1/179 (0%)
Query: 114 NLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
N+ + L N I + + F+N NK+ +I F L L L LS+N +
Sbjct: 127 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 186
Query: 174 MSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL-RFINITAFYGX 232
L FE L L L +++N LS+I TF +L L L N L R +
Sbjct: 187 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 246
Query: 233 XXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + F NLT L + N L T + KL + L N
Sbjct: 247 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSN 305
>BC094737-1|AAH94737.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 85.0 bits (201), Expect = 3e-15
Identities = 85/335 (25%), Positives = 146/335 (43%), Gaps = 20/335 (5%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNY--LYTLPEKLFAN--NTFLE 69
F+ L L+ L ++ N + I S FT L ++ LSN++ L TL + F + ++ L
Sbjct: 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
Query: 70 TIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT--FSLKNLQILKLSDNKINN 127
++++ N++ + SD+F L L++LDL N+I G L+N+ + LS NK
Sbjct: 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPT--QLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
++ N+F R LKN+ + F L+ L LDLSNNN+ ++ E L+
Sbjct: 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLE 530
Query: 186 LLRNLDLKENALSQI--------PDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXX 237
L LDL+ N L+++ P +L L+L N I + F
Sbjct: 531 KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFNEIPVEVFKDLFELKI 590
Query: 238 XXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTL-DYMPKLTIVKLSGNPWHCD 296
+ F+ +L +L L N+ S+ + LT + + NP+ C
Sbjct: 591 IDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCT 650
Query: 297 CHAL-YISAWVRLNEMKIWDYSP--TCVSPWYLEG 328
C ++ + W+ I + S C +P + G
Sbjct: 651 CESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
Score = 79.0 bits (186), Expect = 2e-13
Identities = 75/286 (26%), Positives = 121/286 (42%), Gaps = 17/286 (5%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNY--LEEIDSEAFTST--KKLFHVDLSNNYLYT 56
M DN + + +F L+NLK L L ++ L + +E F S L ++L+ N +
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 57 LPEKLFANNTFLETIDISNNRV-VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSL-KN 114
+ F+ LE +D+ N + + + GL ++ + LS NK + +F+L +
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 115 LQILKLSDNKINNI--SDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNN 172
LQ L L + N+ S + F+ N + NI + L+ L LDL +NN
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
Query: 173 LMSL-------AGVEF-ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L L + F + L L L+L+ N ++IP F D F L+ +DL N L +
Sbjct: 542 LARLWKHANPGGPIYFLKGLSHLHILNLESNGFNEIPVEVFKDLFELKIIDLGLNNLNTL 601
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFS-MLKNLTTLYLDGNMF 269
+ F V K F +NLT L + N F
Sbjct: 602 PASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPF 647
Score = 66.5 bits (155), Expect = 1e-09
Identities = 62/236 (26%), Positives = 107/236 (45%), Gaps = 8/236 (3%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L + + L LK L LQ N L ++ + F L + L +N + + F
Sbjct: 85 NTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFV 144
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQN---GTFSLKNLQILKL 120
L T+D+S+N + + + L +LQ L LS NKIQ +++ F+ +L+ L+L
Sbjct: 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLEL 204
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKL-KNIPTQLFNNL--KCLIFLDLSNNNLMSLA 177
S N+I S F + +L ++ +L L + L LSN+ L + +
Sbjct: 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTS 264
Query: 178 GVEFESLKL--LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
F LK L LDL N L+ + +++F+ LE L N ++ + + +G
Sbjct: 265 NTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHG 320
Score = 60.9 bits (141), Expect = 5e-08
Identities = 40/142 (28%), Positives = 59/142 (41%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N+L+ +P F L LD+ N + L + L +L+ L+L+ N LSQ+ D TF+
Sbjct: 61 NQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFA 120
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
C NL +L L N ++ I F L+NL L L
Sbjct: 121 FCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSN 180
Query: 267 NMFPSLPSRTLDYMPKLTIVKL 288
N +L S LD ++ KL
Sbjct: 181 NKIQALKSEELDIFANSSLKKL 202
Score = 59.7 bits (138), Expect = 1e-07
Identities = 55/207 (26%), Positives = 96/207 (46%), Gaps = 21/207 (10%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLY-TLPEKLFAN--NTFLETIDISN 75
+LK L L N ++E F + +LF + L+N L +L EKL NT + + +SN
Sbjct: 198 SLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSN 257
Query: 76 NRVVYVPSDSFLGLY--SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNA 132
+++ + +FLGL +L +LDLS N + + N +F+ L L+ L N I ++ ++
Sbjct: 258 SQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHS 317
Query: 133 FENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDL 192
R+ K +S +L + F+ LK L +L++
Sbjct: 318 LHGLFNVRYLNLKRSFTKQ---------------SISLASLPKIDDFSFQWLKCLEHLNM 362
Query: 193 KENALSQIPDNTFSDCFNLEKLDLSKN 219
++N + I N F+ NL+ L LS +
Sbjct: 363 EDNDIPGIKSNMFTGLINLKYLSLSNS 389
Score = 54.8 bits (126), Expect = 3e-06
Identities = 46/166 (27%), Positives = 74/166 (44%), Gaps = 5/166 (3%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L++N L LP F + L ++D+ N + + + L L++L+L N++ +
Sbjct: 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS 115
Query: 107 NGTFSL-KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
+ TF+ NL L L N I I +N F N L + L+ L
Sbjct: 116 DKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQE 175
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS-DCFN 210
L LSNN + +L + E L + N LK+ LS FS CF+
Sbjct: 176 LLLSNNKIQAL---KSEELDIFANSSLKKLELSSNQIKEFSPGCFH 218
Score = 46.8 bits (106), Expect = 8e-04
Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINN 127
E D S+ ++ VP D ++ +L+L+ N+++ + F+ L L + N I+
Sbjct: 33 EVADCSHLKLTQVPDDLPT---NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + N+L + + F L L L +N++ + F K L
Sbjct: 90 LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNL 149
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
LDL N LS T NL++L LS NK++
Sbjct: 150 ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQ 184
Score = 46.4 bits (105), Expect = 0.001
Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 2/131 (1%)
Query: 91 SLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLK 150
S ++ D S K+ + + + N+ +L L+ N++ + F N +
Sbjct: 31 SHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
Query: 151 NIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFN 210
+ +L L L L+L +N L L+ F L L L N++ +I +N F N
Sbjct: 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
Query: 211 LEKLDLSKNKL 221
L LDLS N L
Sbjct: 149 LITLDLSHNGL 159
>BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein 1 protein.
Length = 347
Score = 85.0 bits (201), Expect = 3e-15
Identities = 67/261 (25%), Positives = 108/261 (41%), Gaps = 7/261 (2%)
Query: 78 VVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENX 136
+ ++P++ G LQ L LS N ++++ + L++L L+ N + + F+
Sbjct: 80 LTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQAS 139
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
N+L+ + + LK L LDLS N L L + LLR LDL EN
Sbjct: 140 ATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQ 199
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSML 256
L +P + LE+L L NKL+ + V AF L
Sbjct: 200 LETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGL 259
Query: 257 KNLTTLYLDGNMFPSLPSRTLDYM--PKLTI---VKLSGNPWHCDCHALYISAWVRLNEM 311
+ L L L N S+P + P + +SGNPW CD + + W++ +
Sbjct: 260 RQLDMLDLSNNSLASVPEGLWASLGQPNWDMRDGFDISGNPWICDQNLSDLYRWLQAQKD 319
Query: 312 KIWDYSPT-CVSPWYLEGHFL 331
K++ + T C P ++G L
Sbjct: 320 KMFSQNDTRCAGPEAVKGQTL 340
Score = 83.0 bits (196), Expect = 1e-14
Identities = 51/158 (32%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + LP G+F++ L TL L+ N LE ++ K L H+DLS N L LP L A
Sbjct: 126 NALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLA 185
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI-QNGTFSLKNLQILKLSD 122
N T L T+D+ N++ +P D G L+ L L NK+Q + ++ +L+ L L+
Sbjct: 186 NFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNG 245
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNL 160
NK+ ++ AF+ N L ++P L+ +L
Sbjct: 246 NKLARVAAGAFQGLRQLDMLDLSNNSLASVPEGLWASL 283
Score = 80.2 bits (189), Expect = 7e-14
Identities = 53/203 (26%), Positives = 96/203 (47%), Gaps = 1/203 (0%)
Query: 5 HVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFAN 64
++ +LP + + L+ L L N LE + E +L +DL+ N L LP LF
Sbjct: 79 NLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQA 138
Query: 65 NTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDN 123
+ L+T+ + N++ + GL +L LDLS N+++ + G + L+ L L +N
Sbjct: 139 SATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGEN 198
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFES 183
++ + + + NKL+ + L L +L L+ N L +A F+
Sbjct: 199 QLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQG 258
Query: 184 LKLLRNLDLKENALSQIPDNTFS 206
L+ L LDL N+L+ +P+ ++
Sbjct: 259 LRQLDMLDLSNNSLASVPEGLWA 281
Score = 54.0 bits (124), Expect = 6e-06
Identities = 45/174 (25%), Positives = 71/174 (40%), Gaps = 1/174 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N +E L + L+ L L RN L + F ++ L + L N L L
Sbjct: 102 NGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLH 161
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+S NR+ +P L+ LDL +N+++ + L+ L L
Sbjct: 162 GLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEG 221
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSL 176
NK+ + + + NKL + F L+ L LDLSNN+L S+
Sbjct: 222 NKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASV 275
Score = 50.8 bits (116), Expect = 5e-05
Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 1/129 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N +E L L L L L N L ++ + L +DL N L TLP L
Sbjct: 149 ENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLL 208
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
LE + + N++ + D L L+ L L+ NK+ + G F L+ L +L LS
Sbjct: 209 RGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLS 268
Query: 122 DNKINNISD 130
+N + ++ +
Sbjct: 269 NNSLASVPE 277
Score = 37.5 bits (83), Expect = 0.51
Identities = 22/87 (25%), Positives = 40/87 (45%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N +E LP + + L+ L L+ N L+ + + L ++ L+ N L + F
Sbjct: 197 ENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAF 256
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGL 89
L+ +D+SNN + VP + L
Sbjct: 257 QGLRQLDMLDLSNNSLASVPEGLWASL 283
>AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein.
Length = 724
Score = 85.0 bits (201), Expect = 3e-15
Identities = 64/216 (29%), Positives = 98/216 (45%), Gaps = 24/216 (11%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + +L G+FE L L+ L ++ N+L I F L + L NN L LP+K
Sbjct: 151 NRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLC 210
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
++P L LDL N I N++N TF S NL +L +
Sbjct: 211 Q---------------HMPR--------LHWLDLEGNHIHNLRNLTFISCSNLTVLVMRK 247
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
NKIN++++N F NK++N+P +F +LK L L+LS N + + +F+
Sbjct: 248 NKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFD 307
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSK 218
L L++L L+ +S I F NL + K
Sbjct: 308 YLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIYFKK 343
Score = 83.8 bits (198), Expect = 6e-15
Identities = 61/231 (26%), Positives = 104/231 (45%), Gaps = 2/231 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N + LP F N L+ + + NN++ + +F GL SL L LS N+I ++
Sbjct: 98 MSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLK 157
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQ-LFNNLKCLI 164
G F L L+ L + DN ++ IS F N L +P + L ++ L
Sbjct: 158 PGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLH 217
Query: 165 FLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+LDL N++ +L + F S L L +++N ++ + +NTF+ L++LDL NK+ +
Sbjct: 218 WLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENL 277
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSR 275
F ++ F L L +L L+G ++ R
Sbjct: 278 PPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQR 328
Score = 71.7 bits (168), Expect = 3e-11
Identities = 57/247 (23%), Positives = 102/247 (41%), Gaps = 2/247 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N+ + LQ N + ++ + F + L + L NN + ++ F L + +S+NR+
Sbjct: 94 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 153
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAF-ENX 136
++ F L+ L+ L + N + I TF L +L +L L +N + + D ++
Sbjct: 154 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 213
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
+ N + N+ F + L L + N + L F L+ L LDL N
Sbjct: 214 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNK 273
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSML 256
+ +P F D L +L+LS N ++ I F + + F L
Sbjct: 274 IENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRMFRPL 333
Query: 257 KNLTTLY 263
NL+ +Y
Sbjct: 334 MNLSHIY 340
Score = 47.6 bits (108), Expect = 5e-04
Identities = 38/146 (26%), Positives = 57/146 (39%), Gaps = 1/146 (0%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N ++ +P F N L L L NN + S++ F L L L L N ++ + F
Sbjct: 103 NLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFE 162
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSM-LKNLTTLYLD 265
D LE L + N L I+ FYG + K + L L L+
Sbjct: 163 DLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLE 222
Query: 266 GNMFPSLPSRTLDYMPKLTIVKLSGN 291
GN +L + T LT++ + N
Sbjct: 223 GNHIHNLRNLTFISCSNLTVLVMRKN 248
Score = 45.2 bits (102), Expect = 0.003
Identities = 46/179 (25%), Positives = 66/179 (36%), Gaps = 1/179 (0%)
Query: 114 NLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
N+ + L N I + + F+N NK+ +I F L L L LS+N +
Sbjct: 94 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 153
Query: 174 MSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL-RFINITAFYGX 232
L FE L L L +++N LS+I TF +L L L N L R +
Sbjct: 154 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 213
Query: 233 XXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + F NLT L + N L T + KL + L N
Sbjct: 214 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSN 272
>AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein protein.
Length = 347
Score = 85.0 bits (201), Expect = 3e-15
Identities = 67/261 (25%), Positives = 108/261 (41%), Gaps = 7/261 (2%)
Query: 78 VVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENX 136
+ ++P++ G LQ L LS N ++++ + L++L L+ N + + F+
Sbjct: 80 LTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQAS 139
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
N+L+ + + LK L LDLS N L L + LLR LDL EN
Sbjct: 140 ATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQ 199
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSML 256
L +P + LE+L L NKL+ + V AF L
Sbjct: 200 LETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGL 259
Query: 257 KNLTTLYLDGNMFPSLPSRTLDYM--PKLTI---VKLSGNPWHCDCHALYISAWVRLNEM 311
+ L L L N S+P + P + +SGNPW CD + + W++ +
Sbjct: 260 RQLDMLDLSNNSLASVPEGLWASLGQPNWDMRDGFDISGNPWICDQNLSDLYRWLQAQKD 319
Query: 312 KIWDYSPT-CVSPWYLEGHFL 331
K++ + T C P ++G L
Sbjct: 320 KMFSQNDTRCAGPEAVKGQTL 340
Score = 83.0 bits (196), Expect = 1e-14
Identities = 51/158 (32%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + LP G+F++ L TL L+ N LE ++ K L H+DLS N L LP L A
Sbjct: 126 NALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLA 185
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI-QNGTFSLKNLQILKLSD 122
N T L T+D+ N++ +P D G L+ L L NK+Q + ++ +L+ L L+
Sbjct: 186 NFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNG 245
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNL 160
NK+ ++ AF+ N L ++P L+ +L
Sbjct: 246 NKLARVAAGAFQGLRQLDMLDLSNNSLASVPEGLWASL 283
Score = 80.2 bits (189), Expect = 7e-14
Identities = 53/203 (26%), Positives = 96/203 (47%), Gaps = 1/203 (0%)
Query: 5 HVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFAN 64
++ +LP + + L+ L L N LE + E +L +DL+ N L LP LF
Sbjct: 79 NLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQA 138
Query: 65 NTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDN 123
+ L+T+ + N++ + GL +L LDLS N+++ + G + L+ L L +N
Sbjct: 139 SATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGEN 198
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFES 183
++ + + + NKL+ + L L +L L+ N L +A F+
Sbjct: 199 QLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQG 258
Query: 184 LKLLRNLDLKENALSQIPDNTFS 206
L+ L LDL N+L+ +P+ ++
Sbjct: 259 LRQLDMLDLSNNSLASVPEGLWA 281
Score = 54.0 bits (124), Expect = 6e-06
Identities = 45/174 (25%), Positives = 71/174 (40%), Gaps = 1/174 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N +E L + L+ L L RN L + F ++ L + L N L L
Sbjct: 102 NGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLH 161
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
L +D+S NR+ +P L+ LDL +N+++ + L+ L L
Sbjct: 162 GLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEG 221
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSL 176
NK+ + + + NKL + F L+ L LDLSNN+L S+
Sbjct: 222 NKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASV 275
Score = 50.8 bits (116), Expect = 5e-05
Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 1/129 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N +E L L L L L N L ++ + L +DL N L TLP L
Sbjct: 149 ENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLL 208
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
LE + + N++ + D L L+ L L+ NK+ + G F L+ L +L LS
Sbjct: 209 RGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLS 268
Query: 122 DNKINNISD 130
+N + ++ +
Sbjct: 269 NNSLASVPE 277
Score = 37.5 bits (83), Expect = 0.51
Identities = 22/87 (25%), Positives = 40/87 (45%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N +E LP + + L+ L L+ N L+ + + L ++ L+ N L + F
Sbjct: 197 ENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAF 256
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGL 89
L+ +D+SNN + VP + L
Sbjct: 257 QGLRQLDMLDLSNNSLASVPEGLWASL 283
>AF190500-1|AAG17167.1| 757|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 protein.
Length = 757
Score = 85.0 bits (201), Expect = 3e-15
Identities = 64/216 (29%), Positives = 98/216 (45%), Gaps = 24/216 (11%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + +L G+FE L L+ L ++ N+L I F L + L NN L LP+K
Sbjct: 184 NRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLC 243
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
++P L LDL N I N++N TF S NL +L +
Sbjct: 244 Q---------------HMPR--------LHWLDLEGNHIHNLRNLTFISCSNLTVLVMRK 280
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
NKIN++++N F NK++N+P +F +LK L L+LS N + + +F+
Sbjct: 281 NKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFD 340
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSK 218
L L++L L+ +S I F NL + K
Sbjct: 341 YLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIYFKK 376
Score = 83.8 bits (198), Expect = 6e-15
Identities = 61/231 (26%), Positives = 104/231 (45%), Gaps = 2/231 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N + LP F N L+ + + NN++ + +F GL SL L LS N+I ++
Sbjct: 131 MSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLK 190
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQ-LFNNLKCLI 164
G F L L+ L + DN ++ IS F N L +P + L ++ L
Sbjct: 191 PGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLH 250
Query: 165 FLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+LDL N++ +L + F S L L +++N ++ + +NTF+ L++LDL NK+ +
Sbjct: 251 WLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENL 310
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSR 275
F ++ F L L +L L+G ++ R
Sbjct: 311 PPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQR 361
Score = 71.7 bits (168), Expect = 3e-11
Identities = 57/247 (23%), Positives = 102/247 (41%), Gaps = 2/247 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N+ + LQ N + ++ + F + L + L NN + ++ F L + +S+NR+
Sbjct: 127 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 186
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAF-ENX 136
++ F L+ L+ L + N + I TF L +L +L L +N + + D ++
Sbjct: 187 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 246
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
+ N + N+ F + L L + N + L F L+ L LDL N
Sbjct: 247 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNK 306
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSML 256
+ +P F D L +L+LS N ++ I F + + F L
Sbjct: 307 IENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRMFRPL 366
Query: 257 KNLTTLY 263
NL+ +Y
Sbjct: 367 MNLSHIY 373
Score = 47.6 bits (108), Expect = 5e-04
Identities = 38/146 (26%), Positives = 57/146 (39%), Gaps = 1/146 (0%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N ++ +P F N L L L NN + S++ F L L L L N ++ + F
Sbjct: 136 NLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFE 195
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSM-LKNLTTLYLD 265
D LE L + N L I+ FYG + K + L L L+
Sbjct: 196 DLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLE 255
Query: 266 GNMFPSLPSRTLDYMPKLTIVKLSGN 291
GN +L + T LT++ + N
Sbjct: 256 GNHIHNLRNLTFISCSNLTVLVMRKN 281
Score = 45.2 bits (102), Expect = 0.003
Identities = 46/179 (25%), Positives = 66/179 (36%), Gaps = 1/179 (0%)
Query: 114 NLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
N+ + L N I + + F+N NK+ +I F L L L LS+N +
Sbjct: 127 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 186
Query: 174 MSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL-RFINITAFYGX 232
L FE L L L +++N LS+I TF +L L L N L R +
Sbjct: 187 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 246
Query: 233 XXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + F NLT L + N L T + KL + L N
Sbjct: 247 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSN 305
>AB208943-1|BAD92180.1| 627|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 variant
protein.
Length = 627
Score = 85.0 bits (201), Expect = 3e-15
Identities = 64/216 (29%), Positives = 98/216 (45%), Gaps = 24/216 (11%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + +L G+FE L L+ L ++ N+L I F L + L NN L LP+K
Sbjct: 54 NRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLC 113
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
++P L LDL N I N++N TF S NL +L +
Sbjct: 114 Q---------------HMPR--------LHWLDLEGNHIHNLRNLTFISCSNLTVLVMRK 150
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
NKIN++++N F NK++N+P +F +LK L L+LS N + + +F+
Sbjct: 151 NKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFD 210
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSK 218
L L++L L+ +S I F NL + K
Sbjct: 211 YLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIYFKK 246
Score = 75.4 bits (177), Expect = 2e-12
Identities = 54/205 (26%), Positives = 93/205 (45%), Gaps = 2/205 (0%)
Query: 73 ISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDN 131
+ NN++ + +F GL SL L LS N+I ++ G F L L+ L + DN ++ IS
Sbjct: 27 LQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPP 86
Query: 132 AFENXXXXXXXXXDRNKLKNIPTQ-LFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNL 190
F N L +P + L ++ L +LDL N++ +L + F S L L
Sbjct: 87 TFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVL 146
Query: 191 DLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHF 250
+++N ++ + +NTF+ L++LDL NK+ + F ++
Sbjct: 147 VMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQA 206
Query: 251 KAFSMLKNLTTLYLDGNMFPSLPSR 275
F L L +L L+G ++ R
Sbjct: 207 NQFDYLVKLKSLSLEGIEISNIQQR 231
>AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein.
Length = 1618
Score = 85.0 bits (201), Expect = 3e-15
Identities = 45/133 (33%), Positives = 74/133 (55%), Gaps = 1/133 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ + F L L+ L+L N + ++ AF K+L + L+ N L+ LPE LF
Sbjct: 155 NNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQLHMLPELLFQ 214
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
NN L +D+S N + +P +F G L+ L L KN+I I+ G F +L+ L++L L++
Sbjct: 215 NNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNN 274
Query: 123 NKINNISDNAFEN 135
N I I ++F +
Sbjct: 275 NNITTIPVSSFNH 287
Score = 83.4 bits (197), Expect = 8e-15
Identities = 57/198 (28%), Positives = 87/198 (43%), Gaps = 3/198 (1%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N + I F LK L L L N + + F+ +K L L L N L +P+ F
Sbjct: 155 NNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQLHMLPELLFQ 214
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
+ L +LDLS+N ++ I AF G + AF L+ L L L+
Sbjct: 215 NNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNN 274
Query: 267 NMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYL 326
N ++P + ++MPKL +L N CDCH ++S W+R + C P L
Sbjct: 275 NNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLR--QRPTIGLFTQCSGPASL 332
Query: 327 EGHFLKKLKFPEL-CAGQ 343
G + +++ E C+GQ
Sbjct: 333 RGLNVAEVQKSEFSCSGQ 350
Score = 78.6 bits (185), Expect = 2e-13
Identities = 54/225 (24%), Positives = 99/225 (44%), Gaps = 3/225 (1%)
Query: 166 LDLSNNNLMSLAGVE-FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L L+NN + L F+ L L+ ++L N +S+I D F ++ +L L+ N+L I
Sbjct: 629 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 688
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
F G +H +F+ L+N+ L L N ++ D + L+
Sbjct: 689 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 748
Query: 285 IVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPELCAGQW 344
+ L NP++C+C ++ W+R + KI +P C +P +L L+ + FP+ +
Sbjct: 749 TLNLLANPFNCNCQLAWLGGWLR--KRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEG 806
Query: 345 ASMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWPIPVSESILDTH 389
PR Q A +V RC + P + +++ + +
Sbjct: 807 QEEGGCLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKNVTELY 851
Score = 74.9 bits (176), Expect = 3e-12
Identities = 44/136 (32%), Positives = 71/136 (52%), Gaps = 1/136 (0%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
L+L+ N I I F+ LK L++L+L +N+I + AF++ +RN+L +P
Sbjct: 150 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQLHMLP 209
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
LF N + L LDLS N + ++ F L+NL L +N +S I + F LE
Sbjct: 210 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 269
Query: 214 LDLSKNKLRFINITAF 229
L L+ N + I +++F
Sbjct: 270 LTLNNNNITTIPVSSF 285
Score = 73.3 bits (172), Expect = 8e-12
Identities = 80/348 (22%), Positives = 143/348 (41%), Gaps = 23/348 (6%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ +P F +LK L+L +N + I+ AF + + L + L+NN + T+P F
Sbjct: 226 ENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSF 285
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
+ L T + +N + D L S + + +G SL+ L + ++
Sbjct: 286 NHMPKLRTFRLHSNHLF---CDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQK 342
Query: 123 NKIN-------------NISDNAFENXXXXXXXXXD-RNK-LKNIPTQLFNNLKCLIFLD 167
++ + +S + D R K L IP L + I L+
Sbjct: 343 SEFSCSGQGEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMT-EIRLE 401
Query: 168 LSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINIT 227
L N + S+ F + LR +DL N +++I + F +L L L NK+ +
Sbjct: 402 L--NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRG 459
Query: 228 AFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVK 287
F G + AF L+NL+ L L N SL T + + +
Sbjct: 460 VFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLH 519
Query: 288 LSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLK 335
L+ NP+ CDC+ +++ ++R N ++ C SP L + ++K
Sbjct: 520 LAQNPFICDCNLKWLADFLRTNPIE--TSGARCASPRRLANKRIGQIK 565
Score = 68.9 bits (161), Expect = 2e-10
Identities = 39/126 (30%), Positives = 67/126 (53%), Gaps = 2/126 (1%)
Query: 3 DNHVEYLPG-GIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKL 61
+N + L G+F+ L +LK + L N + EI+ AF + + L+ N L ++ +
Sbjct: 633 NNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGM 692
Query: 62 FANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKL 120
F L T+ + NNR+ + +DSF GL ++++L L N+I + G F +L++L L L
Sbjct: 693 FRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNL 752
Query: 121 SDNKIN 126
N N
Sbjct: 753 LANPFN 758
Score = 66.9 bits (156), Expect = 7e-10
Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 1/126 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N + + G F+ + L+ LRL RN L + F + + L +DLS N + +P K
Sbjct: 176 LMENQIGVVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRK 235
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
F T L+ + + N++ + +F L L++L L+ N I I +F+ + L+ +
Sbjct: 236 AFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFR 295
Query: 120 LSDNKI 125
L N +
Sbjct: 296 LHSNHL 301
Score = 60.5 bits (140), Expect = 6e-08
Identities = 43/156 (27%), Positives = 70/156 (44%), Gaps = 1/156 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L N + I F K+L + L N + + F + LE + ++ N++
Sbjct: 146 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQL 205
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXX 137
+P F +L LDLS+N IQ I F +L+ L+L N+I+ I + AF
Sbjct: 206 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 265
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ N + IP FN++ L L +N+L
Sbjct: 266 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 301
Score = 58.8 bits (136), Expect = 2e-07
Identities = 38/127 (29%), Positives = 63/127 (49%), Gaps = 2/127 (1%)
Query: 95 LDLSKNKIQNIQ-NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNI 152
L L+ N+I ++ G F L +L+ + LS+NK++ I D AFE N+L++I
Sbjct: 629 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 688
Query: 153 PTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLE 212
+ +F L L L L NN + + F L+ +R L L +N ++ + F +L
Sbjct: 689 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 748
Query: 213 KLDLSKN 219
L+L N
Sbjct: 749 TLNLLAN 755
Score = 57.6 bits (133), Expect = 4e-07
Identities = 77/338 (22%), Positives = 137/338 (40%), Gaps = 42/338 (12%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N +E + G+F L L+TL L+ N + I +++FT + + + L +N + T+ F
Sbjct: 683 NQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFD 742
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLK-NLQILKLSD 122
L T+++ N ++LG + + ++ N QN F + LQ + D
Sbjct: 743 TLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNP--RCQNPDFLRQIPLQDVAFPD 800
Query: 123 NKINNISDNAF---------ENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ + E L+ +P + N+ L +LD N
Sbjct: 801 FRCEEGQEEGGCLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKNVTEL-YLD---GNQ 856
Query: 174 MSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXX 233
+L + + K L+ +DL N +S + +++F++ L L LS N L+ I AF G
Sbjct: 857 FTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQG-- 914
Query: 234 XXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPW 293
L++L L L GN +L + L+ + + NP
Sbjct: 915 ----------------------LRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 952
Query: 294 HCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFL 331
+CDCH ++S+WV+ + C P +EG L
Sbjct: 953 YCDCHLRWLSSWVKTGYKE--PGIARCAGPQDMEGKLL 988
Score = 55.2 bits (127), Expect = 2e-06
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 5/124 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+ H+ LP GI + N+ L L N + + T K L VDLSNN + +L F
Sbjct: 833 NKHLRALPKGIPK---NVTELYLDGNQFTLVPGQLSTF-KYLQLVDLSNNKISSLSNSSF 888
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
N + L T+ +S N + +P +F GL SL++L L N I +Q G F+ + +L L +
Sbjct: 889 TNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIG 948
Query: 122 DNKI 125
N +
Sbjct: 949 ANPL 952
Score = 54.4 bits (125), Expect = 4e-06
Identities = 39/152 (25%), Positives = 67/152 (44%), Gaps = 1/152 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L+ N + + + FA L + + N++ V +F + L+ L L++N++ +
Sbjct: 150 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQLHMLP 209
Query: 107 NGTFSLKN-LQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
F L L LS+N I I AF D+N++ I F L+ L
Sbjct: 210 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 269
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
L L+NNN+ ++ F + LR L N L
Sbjct: 270 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 301
>AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein.
Length = 1534
Score = 84.6 bits (200), Expect = 3e-15
Identities = 57/198 (28%), Positives = 88/198 (44%), Gaps = 3/198 (1%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N + I F LK L L L N + ++ F+ +K L L L N L +P+ F
Sbjct: 71 NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQ 130
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
+ L +LDLS+N ++ I AF G + AF L+ L L L+
Sbjct: 131 NNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALRGLEVLTLNN 190
Query: 267 NMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYL 326
N ++P + ++MPKL +L N CDCH ++S W+R + C P L
Sbjct: 191 NNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLR--QRPTIGLFTQCSGPASL 248
Query: 327 EGHFLKKLKFPEL-CAGQ 343
G + +++ E C+GQ
Sbjct: 249 RGLNVAEVQKSEFSCSGQ 266
Score = 84.6 bits (200), Expect = 3e-15
Identities = 45/133 (33%), Positives = 74/133 (55%), Gaps = 1/133 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ + F L L+ L+L N + ++ AF K+L + L+ N L+ LPE LF
Sbjct: 71 NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQ 130
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
NN L +D+S N + +P +F G L+ L L KN+I I+ G F +L+ L++L L++
Sbjct: 131 NNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALRGLEVLTLNN 190
Query: 123 NKINNISDNAFEN 135
N I I ++F +
Sbjct: 191 NNITTIPVSSFNH 203
Score = 78.6 bits (185), Expect = 2e-13
Identities = 54/225 (24%), Positives = 99/225 (44%), Gaps = 3/225 (1%)
Query: 166 LDLSNNNLMSLAGVE-FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L L+NN + L F+ L L+ ++L N +S+I D F ++ +L L+ N+L I
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLT 284
F G +H +F+ L+N+ L L N ++ D + L+
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 285 IVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPELCAGQW 344
+ L NP++C+C ++ W+R + KI +P C +P +L L+ + FP+ +
Sbjct: 665 TLNLLANPFNCNCQLAWLGGWLR--KRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEG 722
Query: 345 ASMVNLSPRLPIQQLLALNVSVNRCQMDGVIMWPIPVSESILDTH 389
PR Q A +V RC + P + +++ + +
Sbjct: 723 QEEGGCLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKNVTELY 767
Score = 74.9 bits (176), Expect = 3e-12
Identities = 81/348 (23%), Positives = 143/348 (41%), Gaps = 23/348 (6%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ +P F +LK LRL +N + I+ AF + + L + L+NN + T+P F
Sbjct: 142 ENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSF 201
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
+ L T + +N + D L S + + +G SL+ L + ++
Sbjct: 202 NHMPKLRTFRLHSNHLF---CDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQK 258
Query: 123 NKIN-------------NISDNAFENXXXXXXXXXD-RNK-LKNIPTQLFNNLKCLIFLD 167
++ + +S + D R K L IP L + I L+
Sbjct: 259 SEFSCSGQGEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMT-EIRLE 317
Query: 168 LSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINIT 227
L N + S+ F + LR +DL N +++I + F +L L L NK+ +
Sbjct: 318 L--NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRG 375
Query: 228 AFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVK 287
F G + AF L+NL+ L L N SL T + + +
Sbjct: 376 VFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLH 435
Query: 288 LSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLK 335
L+ NP+ CDC+ +++ ++R N ++ C SP L + ++K
Sbjct: 436 LAQNPFICDCNLKWLADFLRTNPIE--TSGARCASPRRLANKRIGQIK 481
Score = 74.5 bits (175), Expect = 4e-12
Identities = 44/136 (32%), Positives = 71/136 (52%), Gaps = 1/136 (0%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
L+L+ N I I F+ LK L++L+L +N+I + AF++ +RN+L +P
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
LF N + L LDLS N + ++ F L+NL L +N +S I + F LE
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALRGLEV 185
Query: 214 LDLSKNKLRFINITAF 229
L L+ N + I +++F
Sbjct: 186 LTLNNNNITTIPVSSF 201
Score = 68.9 bits (161), Expect = 2e-10
Identities = 39/126 (30%), Positives = 67/126 (53%), Gaps = 2/126 (1%)
Query: 3 DNHVEYLPG-GIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKL 61
+N + L G+F+ L +LK + L N + EI+ AF + + L+ N L ++ +
Sbjct: 549 NNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGM 608
Query: 62 FANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKL 120
F L T+ + NNR+ + +DSF GL ++++L L N+I + G F +L++L L L
Sbjct: 609 FRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNL 668
Query: 121 SDNKIN 126
N N
Sbjct: 669 LANPFN 674
Score = 65.7 bits (153), Expect = 2e-09
Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 1/126 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N + + G F+ + L+ LRL RN L + F + + L +DLS N + +P K
Sbjct: 92 LMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRK 151
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
F T L+ + + N++ + +F L L++L L+ N I I +F+ + L+ +
Sbjct: 152 AFRGATDLKNLRLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFR 211
Query: 120 LSDNKI 125
L N +
Sbjct: 212 LHSNHL 217
Score = 60.9 bits (141), Expect = 5e-08
Identities = 43/156 (27%), Positives = 70/156 (44%), Gaps = 1/156 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N + L L N + I F K+L + L N + + F + LE + ++ N++
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXX 137
+P F +L LDLS+N IQ I F +L+ L+L N+I+ I + AF
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALR 181
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ N + IP FN++ L L +N+L
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 58.8 bits (136), Expect = 2e-07
Identities = 38/127 (29%), Positives = 63/127 (49%), Gaps = 2/127 (1%)
Query: 95 LDLSKNKIQNIQ-NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNI 152
L L+ N+I ++ G F L +L+ + LS+NK++ I D AFE N+L++I
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 153 PTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLE 212
+ +F L L L L NN + + F L+ +R L L +N ++ + F +L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 213 KLDLSKN 219
L+L N
Sbjct: 665 TLNLLAN 671
Score = 57.6 bits (133), Expect = 4e-07
Identities = 77/338 (22%), Positives = 137/338 (40%), Gaps = 42/338 (12%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N +E + G+F L L+TL L+ N + I +++FT + + + L +N + T+ F
Sbjct: 599 NQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFD 658
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLK-NLQILKLSD 122
L T+++ N ++LG + + ++ N QN F + LQ + D
Sbjct: 659 TLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNP--RCQNPDFLRQIPLQDVAFPD 716
Query: 123 NKINNISDNAF---------ENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
+ + E L+ +P + N+ L +LD N
Sbjct: 717 FRCEEGQEEGGCLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKNVTEL-YLD---GNQ 772
Query: 174 MSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXX 233
+L + + K L+ +DL N +S + +++F++ L L LS N L+ I AF G
Sbjct: 773 FTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQG-- 830
Query: 234 XXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPW 293
L++L L L GN +L + L+ + + NP
Sbjct: 831 ----------------------LRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Query: 294 HCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFL 331
+CDCH ++S+WV+ + C P +EG L
Sbjct: 869 YCDCHLRWLSSWVKTGYKE--PGIARCAGPQDMEGKLL 904
Score = 55.2 bits (127), Expect = 2e-06
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 5/124 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+ H+ LP GI + N+ L L N + + T K L VDLSNN + +L F
Sbjct: 749 NKHLRALPKGIPK---NVTELYLDGNQFTLVPGQLSTF-KYLQLVDLSNNKISSLSNSSF 804
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
N + L T+ +S N + +P +F GL SL++L L N I +Q G F+ + +L L +
Sbjct: 805 TNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIG 864
Query: 122 DNKI 125
N +
Sbjct: 865 ANPL 868
Score = 54.0 bits (124), Expect = 6e-06
Identities = 39/152 (25%), Positives = 67/152 (44%), Gaps = 1/152 (0%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L+ N + + + FA L + + N++ V +F + L+ L L++N++ +
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 107 NGTFSLKN-LQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
F L L LS+N I I AF D+N++ I F L+ L
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALRGLEV 185
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
L L+NNN+ ++ F + LR L N L
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
>U88879-1|AAC34134.1| 904|Homo sapiens Toll-like receptor 3
protein.
Length = 904
Score = 84.2 bits (199), Expect = 5e-15
Identities = 85/335 (25%), Positives = 146/335 (43%), Gaps = 20/335 (5%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNY--LYTLPEKLFAN--NTFLE 69
F+ L L+ L ++ N + I S FT L ++ LSN++ L TL + F + ++ L
Sbjct: 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
Query: 70 TIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT--FSLKNLQILKLSDNKINN 127
++++ N++ + SD+F L L++LDL N+I G L+N+ + LS NK
Sbjct: 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPT--QLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
++ N+F R LKN+ + F L+ L LDLSNNN+ ++ E L+
Sbjct: 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLE 530
Query: 186 LLRNLDLKENALSQI--------PDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXX 237
L LDL+ N L+++ P +L L+L N I + F
Sbjct: 531 KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKI 590
Query: 238 XXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTL-DYMPKLTIVKLSGNPWHCD 296
+ F+ +L +L L N+ S+ + LT + + NP+ C
Sbjct: 591 IDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCT 650
Query: 297 CHAL-YISAWVRLNEMKIWDYSP--TCVSPWYLEG 328
C ++ + W+ I + S C +P + G
Sbjct: 651 CESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
Score = 78.6 bits (185), Expect = 2e-13
Identities = 75/286 (26%), Positives = 120/286 (41%), Gaps = 17/286 (5%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNY--LEEIDSEAFTST--KKLFHVDLSNNYLYT 56
M DN + + +F L+NLK L L ++ L + +E F S L ++L+ N +
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 57 LPEKLFANNTFLETIDISNNRV-VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSL-KN 114
+ F+ LE +D+ N + + + GL ++ + LS NK + +F+L +
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 115 LQILKLSDNKINNI--SDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNN 172
LQ L L + N+ S + F+ N + NI + L+ L LDL +NN
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
Query: 173 LMSL-------AGVEF-ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L L + F + L L L+L+ N +IP F D F L+ +DL N L +
Sbjct: 542 LARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTL 601
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFS-MLKNLTTLYLDGNMF 269
+ F V K F +NLT L + N F
Sbjct: 602 PASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPF 647
Score = 66.5 bits (155), Expect = 1e-09
Identities = 62/236 (26%), Positives = 107/236 (45%), Gaps = 8/236 (3%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L + + L LK L LQ N L ++ + F L + L +N + + F
Sbjct: 85 NTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFV 144
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQN---GTFSLKNLQILKL 120
L T+D+S+N + + + L +LQ L LS NKIQ +++ F+ +L+ L+L
Sbjct: 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLEL 204
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKL-KNIPTQLFNNL--KCLIFLDLSNNNLMSLA 177
S N+I S F + +L ++ +L L + L LSN+ L + +
Sbjct: 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTS 264
Query: 178 GVEFESLKL--LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
F LK L LDL N L+ + +++F+ LE L N ++ + + +G
Sbjct: 265 NTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHG 320
Score = 60.9 bits (141), Expect = 5e-08
Identities = 40/142 (28%), Positives = 59/142 (41%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N+L+ +P F L LD+ N + L + L +L+ L+L+ N LSQ+ D TF+
Sbjct: 61 NQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFA 120
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
C NL +L L N ++ I F L+NL L L
Sbjct: 121 FCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSN 180
Query: 267 NMFPSLPSRTLDYMPKLTIVKL 288
N +L S LD ++ KL
Sbjct: 181 NKIQALKSEELDIFANSSLKKL 202
Score = 59.7 bits (138), Expect = 1e-07
Identities = 55/207 (26%), Positives = 96/207 (46%), Gaps = 21/207 (10%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLY-TLPEKLFAN--NTFLETIDISN 75
+LK L L N ++E F + +LF + L+N L +L EKL NT + + +SN
Sbjct: 198 SLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSN 257
Query: 76 NRVVYVPSDSFLGLY--SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNA 132
+++ + +FLGL +L +LDLS N + + N +F+ L L+ L N I ++ ++
Sbjct: 258 SQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHS 317
Query: 133 FENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDL 192
R+ K +S +L + F+ LK L +L++
Sbjct: 318 LHGLFNVRYLNLKRSFTKQ---------------SISLASLPKIDDFSFQWLKCLEHLNM 362
Query: 193 KENALSQIPDNTFSDCFNLEKLDLSKN 219
++N + I N F+ NL+ L LS +
Sbjct: 363 EDNDIPGIKSNMFTGLINLKYLSLSNS 389
Score = 54.8 bits (126), Expect = 3e-06
Identities = 46/166 (27%), Positives = 74/166 (44%), Gaps = 5/166 (3%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L++N L LP F + L ++D+ N + + + L L++L+L N++ +
Sbjct: 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS 115
Query: 107 NGTFSL-KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
+ TF+ NL L L N I I +N F N L + L+ L
Sbjct: 116 DKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQE 175
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS-DCFN 210
L LSNN + +L + E L + N LK+ LS FS CF+
Sbjct: 176 LLLSNNKIQAL---KSEELDIFANSSLKKLELSSNQIKEFSPGCFH 218
Score = 46.8 bits (106), Expect = 8e-04
Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINN 127
E D S+ ++ VP D ++ +L+L+ N+++ + F+ L L + N I+
Sbjct: 33 EVADCSHLKLTQVPDDLPT---NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + N+L + + F L L L +N++ + F K L
Sbjct: 90 LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNL 149
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
LDL N LS T NL++L LS NK++
Sbjct: 150 ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQ 184
Score = 46.4 bits (105), Expect = 0.001
Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 2/131 (1%)
Query: 91 SLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLK 150
S ++ D S K+ + + + N+ +L L+ N++ + F N +
Sbjct: 31 SHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
Query: 151 NIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFN 210
+ +L L L L+L +N L L+ F L L L N++ +I +N F N
Sbjct: 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
Query: 211 LEKLDLSKNKL 221
L LDLS N L
Sbjct: 149 LITLDLSHNGL 159
>DQ445682-1|ABE01399.1| 904|Homo sapiens Toll-like receptor 3
isoform NT2-N protein.
Length = 904
Score = 84.2 bits (199), Expect = 5e-15
Identities = 85/335 (25%), Positives = 146/335 (43%), Gaps = 20/335 (5%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNY--LYTLPEKLFAN--NTFLE 69
F+ L L+ L ++ N + I S FT L ++ LSN++ L TL + F + ++ L
Sbjct: 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
Query: 70 TIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT--FSLKNLQILKLSDNKINN 127
++++ N++ + SD+F L L++LDL N+I G L+N+ + LS NK
Sbjct: 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPT--QLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
++ N+F R LKN+ + F L+ L LDLSNNN+ ++ E L+
Sbjct: 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLE 530
Query: 186 LLRNLDLKENALSQI--------PDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXX 237
L LDL+ N L+++ P +L L+L N I + F
Sbjct: 531 KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKI 590
Query: 238 XXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTL-DYMPKLTIVKLSGNPWHCD 296
+ F+ +L +L L N+ S+ + LT + + NP+ C
Sbjct: 591 IDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCT 650
Query: 297 CHAL-YISAWVRLNEMKIWDYSP--TCVSPWYLEG 328
C ++ + W+ I + S C +P + G
Sbjct: 651 CESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
Score = 78.6 bits (185), Expect = 2e-13
Identities = 75/286 (26%), Positives = 120/286 (41%), Gaps = 17/286 (5%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNY--LEEIDSEAFTST--KKLFHVDLSNNYLYT 56
M DN + + +F L+NLK L L ++ L + +E F S L ++L+ N +
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 57 LPEKLFANNTFLETIDISNNRV-VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSL-KN 114
+ F+ LE +D+ N + + + GL ++ + LS NK + +F+L +
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 115 LQILKLSDNKINNI--SDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNN 172
LQ L L + N+ S + F+ N + NI + L+ L LDL +NN
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
Query: 173 LMSL-------AGVEF-ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L L + F + L L L+L+ N +IP F D F L+ +DL N L +
Sbjct: 542 LARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTL 601
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFS-MLKNLTTLYLDGNMF 269
+ F V K F +NLT L + N F
Sbjct: 602 PASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPF 647
Score = 66.5 bits (155), Expect = 1e-09
Identities = 62/236 (26%), Positives = 107/236 (45%), Gaps = 8/236 (3%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L + + L LK L LQ N L ++ + F L + L +N + + F
Sbjct: 85 NTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFV 144
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQN---GTFSLKNLQILKL 120
L T+D+S+N + + + L +LQ L LS NKIQ +++ F+ +L+ L+L
Sbjct: 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLEL 204
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKL-KNIPTQLFNNL--KCLIFLDLSNNNLMSLA 177
S N+I S F + +L ++ +L L + L LSN+ L + +
Sbjct: 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTS 264
Query: 178 GVEFESLKL--LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
F LK L LDL N L+ + +++F+ LE L N ++ + + +G
Sbjct: 265 NTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHG 320
Score = 60.9 bits (141), Expect = 5e-08
Identities = 40/142 (28%), Positives = 59/142 (41%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N+L+ +P F L LD+ N + L + L +L+ L+L+ N LSQ+ D TF+
Sbjct: 61 NQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFA 120
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
C NL +L L N ++ I F L+NL L L
Sbjct: 121 FCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSN 180
Query: 267 NMFPSLPSRTLDYMPKLTIVKL 288
N +L S LD ++ KL
Sbjct: 181 NKIQALKSEELDIFANSSLKKL 202
Score = 59.7 bits (138), Expect = 1e-07
Identities = 55/207 (26%), Positives = 96/207 (46%), Gaps = 21/207 (10%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLY-TLPEKLFAN--NTFLETIDISN 75
+LK L L N ++E F + +LF + L+N L +L EKL NT + + +SN
Sbjct: 198 SLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSN 257
Query: 76 NRVVYVPSDSFLGLY--SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNA 132
+++ + +FLGL +L +LDLS N + + N +F+ L L+ L N I ++ ++
Sbjct: 258 SQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHS 317
Query: 133 FENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDL 192
R+ K +S +L + F+ LK L +L++
Sbjct: 318 LHGLFNVRYLNLKRSFTKQ---------------SISLASLPKIDDFSFQWLKCLEHLNM 362
Query: 193 KENALSQIPDNTFSDCFNLEKLDLSKN 219
++N + I N F+ NL+ L LS +
Sbjct: 363 EDNDIPGIKSNMFTGLINLKYLSLSNS 389
Score = 54.8 bits (126), Expect = 3e-06
Identities = 46/166 (27%), Positives = 74/166 (44%), Gaps = 5/166 (3%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L++N L LP F + L ++D+ N + + + L L++L+L N++ +
Sbjct: 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS 115
Query: 107 NGTFSL-KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
+ TF+ NL L L N I I +N F N L + L+ L
Sbjct: 116 DKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQE 175
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS-DCFN 210
L LSNN + +L + E L + N LK+ LS FS CF+
Sbjct: 176 LLLSNNKIQAL---KSEELDIFANSSLKKLELSSNQIKEFSPGCFH 218
Score = 46.8 bits (106), Expect = 8e-04
Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINN 127
E D S+ ++ VP D ++ +L+L+ N+++ + F+ L L + N I+
Sbjct: 33 EVADCSHLKLTQVPDDLPT---NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + N+L + + F L L L +N++ + F K L
Sbjct: 90 LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNL 149
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
LDL N LS T NL++L LS NK++
Sbjct: 150 ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQ 184
Score = 46.4 bits (105), Expect = 0.001
Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 2/131 (1%)
Query: 91 SLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLK 150
S ++ D S K+ + + + N+ +L L+ N++ + F N +
Sbjct: 31 SHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
Query: 151 NIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFN 210
+ +L L L L+L +N L L+ F L L L N++ +I +N F N
Sbjct: 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
Query: 211 LEKLDLSKNKL 221
L LDLS N L
Sbjct: 149 LITLDLSHNGL 159
>BC096335-1|AAH96335.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 84.2 bits (199), Expect = 5e-15
Identities = 85/335 (25%), Positives = 146/335 (43%), Gaps = 20/335 (5%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNY--LYTLPEKLFAN--NTFLE 69
F+ L L+ L ++ N + I S FT L ++ LSN++ L TL + F + ++ L
Sbjct: 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
Query: 70 TIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT--FSLKNLQILKLSDNKINN 127
++++ N++ + SD+F L L++LDL N+I G L+N+ + LS NK
Sbjct: 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPT--QLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
++ N+F R LKN+ + F L+ L LDLSNNN+ ++ E L+
Sbjct: 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLE 530
Query: 186 LLRNLDLKENALSQI--------PDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXX 237
L LDL+ N L+++ P +L L+L N I + F
Sbjct: 531 KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKI 590
Query: 238 XXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTL-DYMPKLTIVKLSGNPWHCD 296
+ F+ +L +L L N+ S+ + LT + + NP+ C
Sbjct: 591 IDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCT 650
Query: 297 CHAL-YISAWVRLNEMKIWDYSP--TCVSPWYLEG 328
C ++ + W+ I + S C +P + G
Sbjct: 651 CESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
Score = 78.6 bits (185), Expect = 2e-13
Identities = 75/286 (26%), Positives = 120/286 (41%), Gaps = 17/286 (5%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNY--LEEIDSEAFTST--KKLFHVDLSNNYLYT 56
M DN + + +F L+NLK L L ++ L + +E F S L ++L+ N +
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 57 LPEKLFANNTFLETIDISNNRV-VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSL-KN 114
+ F+ LE +D+ N + + + GL ++ + LS NK + +F+L +
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 115 LQILKLSDNKINNI--SDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNN 172
LQ L L + N+ S + F+ N + NI + L+ L LDL +NN
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
Query: 173 LMSL-------AGVEF-ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L L + F + L L L+L+ N +IP F D F L+ +DL N L +
Sbjct: 542 LARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTL 601
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFS-MLKNLTTLYLDGNMF 269
+ F V K F +NLT L + N F
Sbjct: 602 PASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPF 647
Score = 66.5 bits (155), Expect = 1e-09
Identities = 62/236 (26%), Positives = 107/236 (45%), Gaps = 8/236 (3%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L + + L LK L LQ N L ++ + F L + L +N + + F
Sbjct: 85 NTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFV 144
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQN---GTFSLKNLQILKL 120
L T+D+S+N + + + L +LQ L LS NKIQ +++ F+ +L+ L+L
Sbjct: 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLEL 204
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKL-KNIPTQLFNNL--KCLIFLDLSNNNLMSLA 177
S N+I S F + +L ++ +L L + L LSN+ L + +
Sbjct: 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTS 264
Query: 178 GVEFESLKL--LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
F LK L LDL N L+ + +++F+ LE L N ++ + + +G
Sbjct: 265 NTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHG 320
Score = 60.9 bits (141), Expect = 5e-08
Identities = 40/142 (28%), Positives = 59/142 (41%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N+L+ +P F L LD+ N + L + L +L+ L+L+ N LSQ+ D TF+
Sbjct: 61 NQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFA 120
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
C NL +L L N ++ I F L+NL L L
Sbjct: 121 FCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSN 180
Query: 267 NMFPSLPSRTLDYMPKLTIVKL 288
N +L S LD ++ KL
Sbjct: 181 NKIQALKSEELDIFANSSLKKL 202
Score = 59.7 bits (138), Expect = 1e-07
Identities = 55/207 (26%), Positives = 96/207 (46%), Gaps = 21/207 (10%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLY-TLPEKLFAN--NTFLETIDISN 75
+LK L L N ++E F + +LF + L+N L +L EKL NT + + +SN
Sbjct: 198 SLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSN 257
Query: 76 NRVVYVPSDSFLGLY--SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNA 132
+++ + +FLGL +L +LDLS N + + N +F+ L L+ L N I ++ ++
Sbjct: 258 SQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHS 317
Query: 133 FENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDL 192
R+ K +S +L + F+ LK L +L++
Sbjct: 318 LHGLFNVRYLNLKRSFTKQ---------------SISLASLPKIDDFSFQWLKCLEHLNM 362
Query: 193 KENALSQIPDNTFSDCFNLEKLDLSKN 219
++N + I N F+ NL+ L LS +
Sbjct: 363 EDNDIPGIKSNMFTGLINLKYLSLSNS 389
Score = 54.8 bits (126), Expect = 3e-06
Identities = 46/166 (27%), Positives = 74/166 (44%), Gaps = 5/166 (3%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L++N L LP F + L ++D+ N + + + L L++L+L N++ +
Sbjct: 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS 115
Query: 107 NGTFSL-KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
+ TF+ NL L L N I I +N F N L + L+ L
Sbjct: 116 DKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQE 175
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS-DCFN 210
L LSNN + +L + E L + N LK+ LS FS CF+
Sbjct: 176 LLLSNNKIQAL---KSEELDIFANSSLKKLELSSNQIKEFSPGCFH 218
Score = 46.8 bits (106), Expect = 8e-04
Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINN 127
E D S+ ++ VP D ++ +L+L+ N+++ + F+ L L + N I+
Sbjct: 33 EVADCSHLKLTQVPDDLPT---NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + N+L + + F L L L +N++ + F K L
Sbjct: 90 LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNL 149
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
LDL N LS T NL++L LS NK++
Sbjct: 150 ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQ 184
Score = 46.4 bits (105), Expect = 0.001
Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 2/131 (1%)
Query: 91 SLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLK 150
S ++ D S K+ + + + N+ +L L+ N++ + F N +
Sbjct: 31 SHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
Query: 151 NIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFN 210
+ +L L L L+L +N L L+ F L L L N++ +I +N F N
Sbjct: 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
Query: 211 LEKLDLSKNKL 221
L LDLS N L
Sbjct: 149 LITLDLSHNGL 159
>BC096334-1|AAH96334.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 84.2 bits (199), Expect = 5e-15
Identities = 85/335 (25%), Positives = 146/335 (43%), Gaps = 20/335 (5%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNY--LYTLPEKLFAN--NTFLE 69
F+ L L+ L ++ N + I S FT L ++ LSN++ L TL + F + ++ L
Sbjct: 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
Query: 70 TIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT--FSLKNLQILKLSDNKINN 127
++++ N++ + SD+F L L++LDL N+I G L+N+ + LS NK
Sbjct: 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPT--QLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
++ N+F R LKN+ + F L+ L LDLSNNN+ ++ E L+
Sbjct: 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLE 530
Query: 186 LLRNLDLKENALSQI--------PDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXX 237
L LDL+ N L+++ P +L L+L N I + F
Sbjct: 531 KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKI 590
Query: 238 XXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTL-DYMPKLTIVKLSGNPWHCD 296
+ F+ +L +L L N+ S+ + LT + + NP+ C
Sbjct: 591 IDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCT 650
Query: 297 CHAL-YISAWVRLNEMKIWDYSP--TCVSPWYLEG 328
C ++ + W+ I + S C +P + G
Sbjct: 651 CESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
Score = 78.6 bits (185), Expect = 2e-13
Identities = 75/286 (26%), Positives = 120/286 (41%), Gaps = 17/286 (5%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNY--LEEIDSEAFTST--KKLFHVDLSNNYLYT 56
M DN + + +F L+NLK L L ++ L + +E F S L ++L+ N +
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 57 LPEKLFANNTFLETIDISNNRV-VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSL-KN 114
+ F+ LE +D+ N + + + GL ++ + LS NK + +F+L +
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 115 LQILKLSDNKINNI--SDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNN 172
LQ L L + N+ S + F+ N + NI + L+ L LDL +NN
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
Query: 173 LMSL-------AGVEF-ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L L + F + L L L+L+ N +IP F D F L+ +DL N L +
Sbjct: 542 LARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTL 601
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFS-MLKNLTTLYLDGNMF 269
+ F V K F +NLT L + N F
Sbjct: 602 PASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPF 647
Score = 66.5 bits (155), Expect = 1e-09
Identities = 62/236 (26%), Positives = 107/236 (45%), Gaps = 8/236 (3%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L + + L LK L LQ N L ++ + F L + L +N + + F
Sbjct: 85 NTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFV 144
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQN---GTFSLKNLQILKL 120
L T+D+S+N + + + L +LQ L LS NKIQ +++ F+ +L+ L+L
Sbjct: 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLEL 204
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKL-KNIPTQLFNNL--KCLIFLDLSNNNLMSLA 177
S N+I S F + +L ++ +L L + L LSN+ L + +
Sbjct: 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTS 264
Query: 178 GVEFESLKL--LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
F LK L LDL N L+ + +++F+ LE L N ++ + + +G
Sbjct: 265 NTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHG 320
Score = 60.9 bits (141), Expect = 5e-08
Identities = 40/142 (28%), Positives = 59/142 (41%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N+L+ +P F L LD+ N + L + L +L+ L+L+ N LSQ+ D TF+
Sbjct: 61 NQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFA 120
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
C NL +L L N ++ I F L+NL L L
Sbjct: 121 FCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSN 180
Query: 267 NMFPSLPSRTLDYMPKLTIVKL 288
N +L S LD ++ KL
Sbjct: 181 NKIQALKSEELDIFANSSLKKL 202
Score = 59.7 bits (138), Expect = 1e-07
Identities = 55/207 (26%), Positives = 96/207 (46%), Gaps = 21/207 (10%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLY-TLPEKLFAN--NTFLETIDISN 75
+LK L L N ++E F + +LF + L+N L +L EKL NT + + +SN
Sbjct: 198 SLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSN 257
Query: 76 NRVVYVPSDSFLGLY--SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNA 132
+++ + +FLGL +L +LDLS N + + N +F+ L L+ L N I ++ ++
Sbjct: 258 SQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHS 317
Query: 133 FENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDL 192
R+ K +S +L + F+ LK L +L++
Sbjct: 318 LHGLFNVRYLNLKRSFTKQ---------------SISLASLPKIDDFSFQWLKCLEHLNM 362
Query: 193 KENALSQIPDNTFSDCFNLEKLDLSKN 219
++N + I N F+ NL+ L LS +
Sbjct: 363 EDNDIPGIKSNMFTGLINLKYLSLSNS 389
Score = 54.8 bits (126), Expect = 3e-06
Identities = 46/166 (27%), Positives = 74/166 (44%), Gaps = 5/166 (3%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L++N L LP F + L ++D+ N + + + L L++L+L N++ +
Sbjct: 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS 115
Query: 107 NGTFSL-KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
+ TF+ NL L L N I I +N F N L + L+ L
Sbjct: 116 DKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQE 175
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS-DCFN 210
L LSNN + +L + E L + N LK+ LS FS CF+
Sbjct: 176 LLLSNNKIQAL---KSEELDIFANSSLKKLELSSNQIKEFSPGCFH 218
Score = 46.8 bits (106), Expect = 8e-04
Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINN 127
E D S+ ++ VP D ++ +L+L+ N+++ + F+ L L + N I+
Sbjct: 33 EVADCSHLKLTQVPDDLPT---NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + N+L + + F L L L +N++ + F K L
Sbjct: 90 LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNL 149
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
LDL N LS T NL++L LS NK++
Sbjct: 150 ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQ 184
Score = 46.4 bits (105), Expect = 0.001
Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 2/131 (1%)
Query: 91 SLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLK 150
S ++ D S K+ + + + N+ +L L+ N++ + F N +
Sbjct: 31 SHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
Query: 151 NIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFN 210
+ +L L L L+L +N L L+ F L L L N++ +I +N F N
Sbjct: 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
Query: 211 LEKLDLSKNKL 221
L LDLS N L
Sbjct: 149 LITLDLSHNGL 159
>BC096333-1|AAH96333.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 84.2 bits (199), Expect = 5e-15
Identities = 85/335 (25%), Positives = 146/335 (43%), Gaps = 20/335 (5%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNY--LYTLPEKLFAN--NTFLE 69
F+ L L+ L ++ N + I S FT L ++ LSN++ L TL + F + ++ L
Sbjct: 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
Query: 70 TIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT--FSLKNLQILKLSDNKINN 127
++++ N++ + SD+F L L++LDL N+I G L+N+ + LS NK
Sbjct: 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPT--QLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
++ N+F R LKN+ + F L+ L LDLSNNN+ ++ E L+
Sbjct: 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLE 530
Query: 186 LLRNLDLKENALSQI--------PDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXX 237
L LDL+ N L+++ P +L L+L N I + F
Sbjct: 531 KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKI 590
Query: 238 XXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTL-DYMPKLTIVKLSGNPWHCD 296
+ F+ +L +L L N+ S+ + LT + + NP+ C
Sbjct: 591 IDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCT 650
Query: 297 CHAL-YISAWVRLNEMKIWDYSP--TCVSPWYLEG 328
C ++ + W+ I + S C +P + G
Sbjct: 651 CESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
Score = 78.6 bits (185), Expect = 2e-13
Identities = 75/286 (26%), Positives = 120/286 (41%), Gaps = 17/286 (5%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNY--LEEIDSEAFTST--KKLFHVDLSNNYLYT 56
M DN + + +F L+NLK L L ++ L + +E F S L ++L+ N +
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 57 LPEKLFANNTFLETIDISNNRV-VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSL-KN 114
+ F+ LE +D+ N + + + GL ++ + LS NK + +F+L +
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 115 LQILKLSDNKINNI--SDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNN 172
LQ L L + N+ S + F+ N + NI + L+ L LDL +NN
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
Query: 173 LMSL-------AGVEF-ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L L + F + L L L+L+ N +IP F D F L+ +DL N L +
Sbjct: 542 LARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTL 601
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFS-MLKNLTTLYLDGNMF 269
+ F V K F +NLT L + N F
Sbjct: 602 PASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPF 647
Score = 66.5 bits (155), Expect = 1e-09
Identities = 62/236 (26%), Positives = 107/236 (45%), Gaps = 8/236 (3%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L + + L LK L LQ N L ++ + F L + L +N + + F
Sbjct: 85 NTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFV 144
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQN---GTFSLKNLQILKL 120
L T+D+S+N + + + L +LQ L LS NKIQ +++ F+ +L+ L+L
Sbjct: 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLEL 204
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKL-KNIPTQLFNNL--KCLIFLDLSNNNLMSLA 177
S N+I S F + +L ++ +L L + L LSN+ L + +
Sbjct: 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTS 264
Query: 178 GVEFESLKL--LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
F LK L LDL N L+ + +++F+ LE L N ++ + + +G
Sbjct: 265 NTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHG 320
Score = 60.9 bits (141), Expect = 5e-08
Identities = 40/142 (28%), Positives = 59/142 (41%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N+L+ +P F L LD+ N + L + L +L+ L+L+ N LSQ+ D TF+
Sbjct: 61 NQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFA 120
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
C NL +L L N ++ I F L+NL L L
Sbjct: 121 FCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSN 180
Query: 267 NMFPSLPSRTLDYMPKLTIVKL 288
N +L S LD ++ KL
Sbjct: 181 NKIQALKSEELDIFANSSLKKL 202
Score = 59.7 bits (138), Expect = 1e-07
Identities = 55/207 (26%), Positives = 96/207 (46%), Gaps = 21/207 (10%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLY-TLPEKLFAN--NTFLETIDISN 75
+LK L L N ++E F + +LF + L+N L +L EKL NT + + +SN
Sbjct: 198 SLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSN 257
Query: 76 NRVVYVPSDSFLGLY--SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNA 132
+++ + +FLGL +L +LDLS N + + N +F+ L L+ L N I ++ ++
Sbjct: 258 SQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHS 317
Query: 133 FENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDL 192
R+ K +S +L + F+ LK L +L++
Sbjct: 318 LHGLFNVRYLNLKRSFTKQ---------------SISLASLPKIDDFSFQWLKCLEHLNM 362
Query: 193 KENALSQIPDNTFSDCFNLEKLDLSKN 219
++N + I N F+ NL+ L LS +
Sbjct: 363 EDNDIPGIKSNMFTGLINLKYLSLSNS 389
Score = 54.8 bits (126), Expect = 3e-06
Identities = 46/166 (27%), Positives = 74/166 (44%), Gaps = 5/166 (3%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L++N L LP F + L ++D+ N + + + L L++L+L N++ +
Sbjct: 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS 115
Query: 107 NGTFSL-KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
+ TF+ NL L L N I I +N F N L + L+ L
Sbjct: 116 DKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQE 175
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS-DCFN 210
L LSNN + +L + E L + N LK+ LS FS CF+
Sbjct: 176 LLLSNNKIQAL---KSEELDIFANSSLKKLELSSNQIKEFSPGCFH 218
Score = 46.8 bits (106), Expect = 8e-04
Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINN 127
E D S+ ++ VP D ++ +L+L+ N+++ + F+ L L + N I+
Sbjct: 33 EVADCSHLKLTQVPDDLPT---NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + N+L + + F L L L +N++ + F K L
Sbjct: 90 LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNL 149
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
LDL N LS T NL++L LS NK++
Sbjct: 150 ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQ 184
Score = 46.4 bits (105), Expect = 0.001
Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 2/131 (1%)
Query: 91 SLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLK 150
S ++ D S K+ + + + N+ +L L+ N++ + F N +
Sbjct: 31 SHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
Query: 151 NIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFN 210
+ +L L L L+L +N L L+ F L L L N++ +I +N F N
Sbjct: 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
Query: 211 LEKLDLSKNKL 221
L LDLS N L
Sbjct: 149 LITLDLSHNGL 159
>BC059372-1|AAH59372.1| 870|Homo sapiens TLR3 protein protein.
Length = 870
Score = 84.2 bits (199), Expect = 5e-15
Identities = 85/335 (25%), Positives = 146/335 (43%), Gaps = 20/335 (5%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNY--LYTLPEKLFAN--NTFLE 69
F+ L L+ L ++ N + I S FT L ++ LSN++ L TL + F + ++ L
Sbjct: 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
Query: 70 TIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT--FSLKNLQILKLSDNKINN 127
++++ N++ + SD+F L L++LDL N+I G L+N+ + LS NK
Sbjct: 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPT--QLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
++ N+F R LKN+ + F L+ L LDLSNNN+ ++ E L+
Sbjct: 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLE 530
Query: 186 LLRNLDLKENALSQI--------PDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXX 237
L LDL+ N L+++ P +L L+L N I + F
Sbjct: 531 KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKI 590
Query: 238 XXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTL-DYMPKLTIVKLSGNPWHCD 296
+ F+ +L +L L N+ S+ + LT + + NP+ C
Sbjct: 591 IDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCT 650
Query: 297 CHAL-YISAWVRLNEMKIWDYSP--TCVSPWYLEG 328
C ++ + W+ I + S C +P + G
Sbjct: 651 CESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
Score = 78.6 bits (185), Expect = 2e-13
Identities = 75/286 (26%), Positives = 120/286 (41%), Gaps = 17/286 (5%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNY--LEEIDSEAFTST--KKLFHVDLSNNYLYT 56
M DN + + +F L+NLK L L ++ L + +E F S L ++L+ N +
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 57 LPEKLFANNTFLETIDISNNRV-VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSL-KN 114
+ F+ LE +D+ N + + + GL ++ + LS NK + +F+L +
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 115 LQILKLSDNKINNI--SDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNN 172
LQ L L + N+ S + F+ N + NI + L+ L LDL +NN
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
Query: 173 LMSL-------AGVEF-ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L L + F + L L L+L+ N +IP F D F L+ +DL N L +
Sbjct: 542 LARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTL 601
Query: 225 NITAFYGXXXXXXXXXXXXXXYEVHFKAFS-MLKNLTTLYLDGNMF 269
+ F V K F +NLT L + N F
Sbjct: 602 PASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPF 647
Score = 66.5 bits (155), Expect = 1e-09
Identities = 62/236 (26%), Positives = 107/236 (45%), Gaps = 8/236 (3%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L + + L LK L LQ N L ++ + F L + L +N + + F
Sbjct: 85 NTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFV 144
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQN---GTFSLKNLQILKL 120
L T+D+S+N + + + L +LQ L LS NKIQ +++ F+ +L+ L+L
Sbjct: 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLEL 204
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKL-KNIPTQLFNNL--KCLIFLDLSNNNLMSLA 177
S N+I S F + +L ++ +L L + L LSN+ L + +
Sbjct: 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTS 264
Query: 178 GVEFESLKL--LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
F LK L LDL N L+ + +++F+ LE L N ++ + + +G
Sbjct: 265 NTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHG 320
Score = 60.9 bits (141), Expect = 5e-08
Identities = 40/142 (28%), Positives = 59/142 (41%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N+L+ +P F L LD+ N + L + L +L+ L+L+ N LSQ+ D TF+
Sbjct: 61 NQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFA 120
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
C NL +L L N ++ I F L+NL L L
Sbjct: 121 FCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSN 180
Query: 267 NMFPSLPSRTLDYMPKLTIVKL 288
N +L S LD ++ KL
Sbjct: 181 NKIQALKSEELDIFANSSLKKL 202
Score = 59.7 bits (138), Expect = 1e-07
Identities = 55/207 (26%), Positives = 96/207 (46%), Gaps = 21/207 (10%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLY-TLPEKLFAN--NTFLETIDISN 75
+LK L L N ++E F + +LF + L+N L +L EKL NT + + +SN
Sbjct: 198 SLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSN 257
Query: 76 NRVVYVPSDSFLGLY--SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNA 132
+++ + +FLGL +L +LDLS N + + N +F+ L L+ L N I ++ ++
Sbjct: 258 SQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHS 317
Query: 133 FENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDL 192
R+ K +S +L + F+ LK L +L++
Sbjct: 318 LHGLFNVRYLNLKRSFTKQ---------------SISLASLPKIDDFSFQWLKCLEHLNM 362
Query: 193 KENALSQIPDNTFSDCFNLEKLDLSKN 219
++N + I N F+ NL+ L LS +
Sbjct: 363 EDNDIPGIKSNMFTGLINLKYLSLSNS 389
Score = 54.8 bits (126), Expect = 3e-06
Identities = 46/166 (27%), Positives = 74/166 (44%), Gaps = 5/166 (3%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
++L++N L LP F + L ++D+ N + + + L L++L+L N++ +
Sbjct: 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS 115
Query: 107 NGTFSL-KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
+ TF+ NL L L N I I +N F N L + L+ L
Sbjct: 116 DKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQE 175
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS-DCFN 210
L LSNN + +L + E L + N LK+ LS FS CF+
Sbjct: 176 LLLSNNKIQAL---KSEELDIFANSSLKKLELSSNQIKEFSPGCFH 218
Score = 46.8 bits (106), Expect = 8e-04
Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINN 127
E D S+ ++ VP D ++ +L+L+ N+++ + F+ L L + N I+
Sbjct: 33 EVADCSHLKLTQVPDDLPT---NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + N+L + + F L L L +N++ + F K L
Sbjct: 90 LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNL 149
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
LDL N LS T NL++L LS NK++
Sbjct: 150 ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQ 184
Score = 46.4 bits (105), Expect = 0.001
Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 2/131 (1%)
Query: 91 SLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLK 150
S ++ D S K+ + + + N+ +L L+ N++ + F N +
Sbjct: 31 SHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
Query: 151 NIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFN 210
+ +L L L L+L +N L L+ F L L L N++ +I +N F N
Sbjct: 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
Query: 211 LEKLDLSKNKL 221
L LDLS N L
Sbjct: 149 LITLDLSHNGL 159
>BC048421-1|AAH48421.1| 453|Homo sapiens LOC150356 protein protein.
Length = 453
Score = 84.2 bits (199), Expect = 5e-15
Identities = 65/222 (29%), Positives = 100/222 (45%), Gaps = 3/222 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH +P F L +L +L LQ + E+++ A +L ++ LS+N L L
Sbjct: 126 NHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALE 185
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L + + N + VP + L SL L L N + + G + L+ + LS
Sbjct: 186 GAPRLGYLYLERNSFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSG 245
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I +S A DRN+L+ +PT L L+ L LS N L +L F+
Sbjct: 246 NRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQ 305
Query: 183 SL-KLLRNLDLKENALSQIPDNTFSDCF-NLEKLDLSKNKLR 222
+ + L++L L + L QI FS L+ L L KN+LR
Sbjct: 306 PVGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLR 347
Score = 70.5 bits (165), Expect = 6e-11
Identities = 81/306 (26%), Positives = 119/306 (38%), Gaps = 34/306 (11%)
Query: 69 ETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINN 127
+ +D+ N VP +F GL L L L I ++ G + L L L LSDN++
Sbjct: 119 QLLDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAG 178
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+S A E +RN +P L L L L +N + LA + + L
Sbjct: 179 LSAAALEGAPRLGYLYLERNSFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRAL 238
Query: 188 R------------------------NLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRF 223
R L L N L ++P L +L LS N LR
Sbjct: 239 RWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRA 298
Query: 224 INITAFYGXXXXXXXXXXXXXXYE-VHFKAFSML-KNLTTLYLDGNMFPSLPSRTLDYMP 281
+ AF E + AFS L L +L+L N +LP+ L +
Sbjct: 299 LRDGAFQPVGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALPA--LPSLS 356
Query: 282 KLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFP-ELC 340
+L ++ LS NP+HCDC L + W+ +++ TC +P G +K E C
Sbjct: 357 QLELIDLSSNPFHCDCQLLPLHRWLTGLNLRV---GATCATPPNARGQRVKAAAAVFEDC 413
Query: 341 AGQWAS 346
G WA+
Sbjct: 414 PG-WAA 418
Score = 50.0 bits (114), Expect = 9e-05
Identities = 50/196 (25%), Positives = 79/196 (40%), Gaps = 5/196 (2%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + L E L L L+RN ++ A + LF + L +N + L
Sbjct: 173 DNQLAGLSAAALEGAPRLGYLYLERNSFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDL 232
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLS 121
L + +S NR+ V + L+ L L +N+++ + G L L L+LS
Sbjct: 233 GRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLS 292
Query: 122 DNKINNISDNAFEN-XXXXXXXXXDRNKLKNIPTQLFNNL-KCLIFLDLSNNNLMSLAGV 179
N + + D AF+ + + L+ I F+ L L L L N L +L +
Sbjct: 293 GNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALPAL 352
Query: 180 EFESLKLLRNLDLKEN 195
SL L +DL N
Sbjct: 353 --PSLSQLELIDLSSN 366
>AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608
protein.
Length = 2623
Score = 83.8 bits (198), Expect = 6e-15
Identities = 50/169 (29%), Positives = 75/169 (44%), Gaps = 8/169 (4%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N L + F+ L L L L +N + ++ F L+ L+ L + N + ++ +TF
Sbjct: 67 NSLVRLMETDFSGLTKLELLMLHSNGIHTIPDKTFSDLQALQVLKMSYNKVRKLQKDTFY 126
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT----- 261
+L +L + N + FIN FYG ++H F L L
Sbjct: 127 GLRSLTRLHMDHNNIEFINPEVFYGLNFLRLVHLEGNQLTKLHPDTFVSLSYLQIFKISF 186
Query: 262 ---LYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVR 307
LYL N SLP + YMP L + L GNPW CDCH ++S W++
Sbjct: 187 IKFLYLSDNFLTSLPQEMVSYMPDLDSLYLHGNPWTCDCHLKWLSDWIQ 235
Score = 68.1 bits (159), Expect = 3e-10
Identities = 50/176 (28%), Positives = 85/176 (48%), Gaps = 12/176 (6%)
Query: 53 YLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS- 111
YL ++P+ + N +E I++ N +V + F GL L++L L N I I + TFS
Sbjct: 47 YLTSIPDSIPPN---VERINLGYNSLVRLMETDFSGLTKLELLMLHSNGIHTIPDKTFSD 103
Query: 112 LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNN 171
L+ LQ+LK+S NK+ + + F D N ++ I ++F L L + L N
Sbjct: 104 LQALQVLKMSYNKVRKLQKDTFYGLRSLTRLHMDHNNIEFINPEVFYGLNFLRLVHLEGN 163
Query: 172 NL--------MSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
L +SL+ ++ + ++ L L +N L+ +P S +L+ L L N
Sbjct: 164 QLTKLHPDTFVSLSYLQIFKISFIKFLYLSDNFLTSLPQEMVSYMPDLDSLYLHGN 219
Score = 58.0 bits (134), Expect = 3e-07
Identities = 38/124 (30%), Positives = 56/124 (45%)
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
++L N+L+ L +F L L L L N + IPD TFSD L+ L +S NK+R +
Sbjct: 62 INLGYNSLVRLMETDFSGLTKLELLMLHSNGIHTIPDKTFSDLQALQVLKMSYNKVRKLQ 121
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
FYG ++ + F L L ++L+GN L T + L I
Sbjct: 122 KDTFYGLRSLTRLHMDHNNIEFINPEVFYGLNFLRLVHLEGNQLTKLHPDTFVSLSYLQI 181
Query: 286 VKLS 289
K+S
Sbjct: 182 FKIS 185
Score = 54.8 bits (126), Expect = 3e-06
Identities = 33/116 (28%), Positives = 61/116 (52%), Gaps = 1/116 (0%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N++ + L N L + F+ KL + L +N ++T+P+K F++ L+ + +S N+V
Sbjct: 58 NVERINLGYNSLVRLMETDFSGLTKLELLMLHSNGIHTIPDKTFSDLQALQVLKMSYNKV 117
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAF 133
+ D+F GL SL L + N I+ I F L L+++ L N++ + + F
Sbjct: 118 RKLQKDTFYGLRSLTRLHMDHNNIEFINPEVFYGLNFLRLVHLEGNQLTKLHPDTF 173
Score = 51.2 bits (117), Expect = 4e-05
Identities = 33/136 (24%), Positives = 63/136 (46%), Gaps = 1/136 (0%)
Query: 91 SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKL 149
+++ ++L N + + FS L L++L L N I+ I D F + NK+
Sbjct: 58 NVERINLGYNSLVRLMETDFSGLTKLELLMLHSNGIHTIPDKTFSDLQALQVLKMSYNKV 117
Query: 150 KNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCF 209
+ + F L+ L L + +NN+ + F L LR + L+ N L+++ +TF
Sbjct: 118 RKLQKDTFYGLRSLTRLHMDHNNIEFINPEVFYGLNFLRLVHLEGNQLTKLHPDTFVSLS 177
Query: 210 NLEKLDLSKNKLRFIN 225
L+ +S K +++
Sbjct: 178 YLQIFKISFIKFLYLS 193
Score = 44.8 bits (101), Expect = 0.003
Identities = 21/98 (21%), Positives = 47/98 (47%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ N + +P F L L+ L++ N + ++ + F + L + + +N + + +
Sbjct: 88 LHSNGIHTIPDKTFSDLQALQVLKMSYNKVRKLQKDTFYGLRSLTRLHMDHNNIEFINPE 147
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLS 98
+F FL + + N++ + D+F+ L LQI +S
Sbjct: 148 VFYGLNFLRLVHLEGNQLTKLHPDTFVSLSYLQIFKIS 185
>BC126464-1|AAI26465.1| 1371|Homo sapiens erbb2 interacting protein
protein.
Length = 1371
Score = 81.8 bits (193), Expect = 2e-14
Identities = 74/270 (27%), Positives = 114/270 (42%), Gaps = 9/270 (3%)
Query: 22 TLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYV 81
TL LE++ E FT K L + L N + LP++LF N L + + +N + +
Sbjct: 26 TLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTL 84
Query: 82 PSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXX 141
P+ S L +L+ LD+SKN IQ + K L I++ S N I+ + D F
Sbjct: 85 PA-SIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPD-GFSQLLNLTQ 142
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
+ L+ +P F L L L+L N L L L L LDL N +++P
Sbjct: 143 LYLNDAFLEFLPAN-FGRLTKLQILELRENQLKMLPKT-MNRLTQLERLDLGSNEFTEVP 200
Query: 202 DNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT 261
+ L++ + N+L F I F G E+ + S +NL
Sbjct: 201 E-VLEQLSGLKEFWMDANRLTF--IPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQD 257
Query: 262 LYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L L N LP T+ + +T +K+ N
Sbjct: 258 LLLSSNSLQQLP-ETIGLLKNITTLKIDEN 286
Score = 74.9 bits (176), Expect = 3e-12
Identities = 74/268 (27%), Positives = 113/268 (42%), Gaps = 9/268 (3%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
+E +P IF L+ L L N +EE+ + F + + L + L +N L TLP + AN
Sbjct: 34 LEQVPKEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTLPASI-ANL 91
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKI 125
L +D+S N + P ++ L I++ S N I + +G L NL L L+D +
Sbjct: 92 INLRELDVSKNGIQEFP-ENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFL 150
Query: 126 NNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
+ N F N+LK +P + N L L LDL +N + V E L
Sbjct: 151 EFLPAN-FGRLTKLQILELRENQLKMLPKTM-NRLTQLERLDLGSNEFTEVPEV-LEQLS 207
Query: 186 LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXX 245
L+ + N L+ IP L LD+SKN + +
Sbjct: 208 GLKEFWMDANRLTFIP-GFIGSLKQLTYLDVSKNNIEMVE--EGISTCENLQDLLLSSNS 264
Query: 246 YEVHFKAFSMLKNLTTLYLDGNMFPSLP 273
+ + +LKN+TTL +D N LP
Sbjct: 265 LQQLPETIGLLKNITTLKIDENQLMYLP 292
Score = 73.3 bits (172), Expect = 8e-12
Identities = 82/311 (26%), Positives = 139/311 (44%), Gaps = 32/311 (10%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + LP I +L+NL+ L + +N ++E E + K L V+ S N + LP+ F
Sbjct: 78 DNDLTTLPASI-ANLINLRELDVSKNGIQEFP-ENIKNCKVLTIVEASVNPISKLPDG-F 134
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
+ L + +++ + ++P++ F L LQIL+L +N+++ + L L+ L L
Sbjct: 135 SQLLNLTQLYLNDAFLEFLPAN-FGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGS 193
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL-MSLAGVEF 181
N+ + + E D N+L IP +LK L +LD+S NN+ M G+
Sbjct: 194 NEFTEVPE-VLEQLSGLKEFWMDANRLTFIPG-FIGSLKQLTYLDVSKNNIEMVEEGIST 251
Query: 182 ------------------ESLKLLRN---LDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
E++ LL+N L + EN L +PD+ ++E+LD S N+
Sbjct: 252 CENLQDLLLSSNSLQQLPETIGLLKNITTLKIDENQLMYLPDS-IGGLISVEELDCSFNE 310
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ + + G + KN+T L+L N +LP D M
Sbjct: 311 VEAL--PSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGD-M 367
Query: 281 PKLTIVKLSGN 291
KL ++ LS N
Sbjct: 368 QKLKVINLSDN 378
Score = 41.1 bits (92), Expect = 0.042
Identities = 31/126 (24%), Positives = 63/126 (50%), Gaps = 6/126 (4%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I L N+ TL++ N L + ++ + +D S N + LP +
Sbjct: 263 NSLQQLPETI-GLLKNITTLKIDENQLMYLP-DSIGGLISVEELDCSFNEVEALPSSI-G 319
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLY-SLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
T L T +N + +P + +G + ++ +L L NK++ + ++ L+++ LSD
Sbjct: 320 QLTNLRTFAADHNYLQQLPPE--IGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSD 377
Query: 123 NKINNI 128
N++ N+
Sbjct: 378 NRLKNL 383
>BC115015-1|AAI15016.1| 1367|Homo sapiens ERBB2IP protein protein.
Length = 1367
Score = 81.8 bits (193), Expect = 2e-14
Identities = 74/270 (27%), Positives = 115/270 (42%), Gaps = 9/270 (3%)
Query: 22 TLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYV 81
TL LE++ E FT K L + L N + LP++LF N L + + +N + +
Sbjct: 26 TLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTL 84
Query: 82 PSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXX 141
P+ S L +L+ LD+SKN IQ + K L I++ S N I+ + D F
Sbjct: 85 PA-SIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPD-GFSQLLNLTQ 142
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
+ L+ +P F+ L L L+L N L L L L LDL N +++P
Sbjct: 143 LYLNDAFLEFLPAN-FDRLTKLQILELRENQLKMLPKT-MNRLTQLERLDLGSNEFTEVP 200
Query: 202 DNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT 261
+ L++ + N+L F I F G E+ + S +NL
Sbjct: 201 E-VLEQLSGLKEFWMDANRLTF--IPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQD 257
Query: 262 LYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L L N LP T+ + +T +K+ N
Sbjct: 258 LLLSSNSLQQLP-ETIGSLKNITTLKIDEN 286
Score = 75.4 bits (177), Expect = 2e-12
Identities = 74/268 (27%), Positives = 113/268 (42%), Gaps = 9/268 (3%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
+E +P IF L+ L L N +EE+ + F + + L + L +N L TLP + AN
Sbjct: 34 LEQVPKEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTLPASI-ANL 91
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKI 125
L +D+S N + P ++ L I++ S N I + +G L NL L L+D +
Sbjct: 92 INLRELDVSKNGIQEFP-ENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFL 150
Query: 126 NNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
+ N F+ N+LK +P + N L L LDL +N + V E L
Sbjct: 151 EFLPAN-FDRLTKLQILELRENQLKMLPKTM-NRLTQLERLDLGSNEFTEVPEV-LEQLS 207
Query: 186 LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXX 245
L+ + N L+ IP L LD+SKN + +
Sbjct: 208 GLKEFWMDANRLTFIP-GFIGSLKQLTYLDVSKNNIEMVE--EGISTCENLQDLLLSSNS 264
Query: 246 YEVHFKAFSMLKNLTTLYLDGNMFPSLP 273
+ + LKN+TTL +D N LP
Sbjct: 265 LQQLPETIGSLKNITTLKIDENQLMYLP 292
Score = 72.5 bits (170), Expect = 1e-11
Identities = 81/311 (26%), Positives = 136/311 (43%), Gaps = 32/311 (10%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + LP I +L+NL+ L + +N ++E E + K L V+ S N + LP+ F
Sbjct: 78 DNDLTTLPASI-ANLINLRELDVSKNGIQEFP-ENIKNCKVLTIVEASVNPISKLPDG-F 134
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
+ L + +++ + ++P++ F L LQIL+L +N+++ + L L+ L L
Sbjct: 135 SQLLNLTQLYLNDAFLEFLPAN-FDRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGS 193
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL-MSLAGVE- 180
N+ + + E D N+L IP +LK L +LD+S NN+ M G+
Sbjct: 194 NEFTEVPE-VLEQLSGLKEFWMDANRLTFIPG-FIGSLKQLTYLDVSKNNIEMVEEGIST 251
Query: 181 --------------------FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
SLK + L + EN L +PD+ ++E+LD S N+
Sbjct: 252 CENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDS-IGGLISVEELDCSFNE 310
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ + + G + KN+T L+L N +LP D M
Sbjct: 311 VEAL--PSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGD-M 367
Query: 281 PKLTIVKLSGN 291
KL ++ LS N
Sbjct: 368 QKLKVINLSDN 378
Score = 43.6 bits (98), Expect = 0.008
Identities = 32/126 (25%), Positives = 64/126 (50%), Gaps = 6/126 (4%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I SL N+ TL++ N L + ++ + +D S N + LP +
Sbjct: 263 NSLQQLPETI-GSLKNITTLKIDENQLMYLP-DSIGGLISVEELDCSFNEVEALPSSI-G 319
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLY-SLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
T L T +N + +P + +G + ++ +L L NK++ + ++ L+++ LSD
Sbjct: 320 QLTNLRTFAADHNYLQQLPPE--IGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSD 377
Query: 123 NKINNI 128
N++ N+
Sbjct: 378 NRLKNL 383
>BC050692-1|AAH50692.1| 633|Homo sapiens ERBB2IP protein protein.
Length = 633
Score = 81.4 bits (192), Expect = 3e-14
Identities = 74/270 (27%), Positives = 114/270 (42%), Gaps = 9/270 (3%)
Query: 22 TLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYV 81
TL LE++ E FT K L + L N + LP++LF N L + + +N + +
Sbjct: 26 TLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTL 84
Query: 82 PSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXX 141
P+ S L +L+ LD+SKN IQ + K L I++ S N I+ + D F
Sbjct: 85 PA-SIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPD-GFSQLLNLTQ 142
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
+ L+ +P F L L L+L N L L L L LDL N +++P
Sbjct: 143 LYLNDAFLEFLPAN-FGRLTKLQILELRENQLKMLPKT-MNRLTQLERLDLGSNEFTEVP 200
Query: 202 DNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT 261
+ L++ + N+L F I F G E+ + S +NL
Sbjct: 201 E-VLEQLSGLKEFWMDANRLTF--IPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQD 257
Query: 262 LYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L L N LP T+ + +T +K+ N
Sbjct: 258 LLLSSNSLQQLP-ETIGSLKNITTLKIDEN 286
Score = 73.7 bits (173), Expect = 6e-12
Identities = 74/268 (27%), Positives = 112/268 (41%), Gaps = 9/268 (3%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
+E +P IF L+ L L N +EE+ + F + + L + L +N L TLP + AN
Sbjct: 34 LEQVPKEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTLPASI-ANL 91
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKI 125
L +D+S N + P ++ L I++ S N I + +G L NL L L+D +
Sbjct: 92 INLRELDVSKNGIQEFP-ENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFL 150
Query: 126 NNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
+ N F N+LK +P + N L L LDL +N + V E L
Sbjct: 151 EFLPAN-FGRLTKLQILELRENQLKMLPKTM-NRLTQLERLDLGSNEFTEVPEV-LEQLS 207
Query: 186 LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXX 245
L+ + N L+ IP L LD+SKN + +
Sbjct: 208 GLKEFWMDANRLTFIP-GFIGSLKQLTYLDVSKNNIEMVE--EGISTCENLQDLLLSSNS 264
Query: 246 YEVHFKAFSMLKNLTTLYLDGNMFPSLP 273
+ + LKN+TTL +D N LP
Sbjct: 265 LQQLPETIGSLKNITTLKIDENQLMYLP 292
Score = 72.5 bits (170), Expect = 1e-11
Identities = 81/311 (26%), Positives = 136/311 (43%), Gaps = 32/311 (10%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + LP I +L+NL+ L + +N ++E E + K L V+ S N + LP+ F
Sbjct: 78 DNDLTTLPASI-ANLINLRELDVSKNGIQEFP-ENIKNCKVLTIVEASVNPISKLPDG-F 134
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
+ L + +++ + ++P++ F L LQIL+L +N+++ + L L+ L L
Sbjct: 135 SQLLNLTQLYLNDAFLEFLPAN-FGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGS 193
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL-MSLAGVE- 180
N+ + + E D N+L IP +LK L +LD+S NN+ M G+
Sbjct: 194 NEFTEVPE-VLEQLSGLKEFWMDANRLTFIPG-FIGSLKQLTYLDVSKNNIEMVEEGIST 251
Query: 181 --------------------FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
SLK + L + EN L +PD+ ++E+LD S N+
Sbjct: 252 CENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDS-IGGLISVEELDCSFNE 310
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ + + G + KN+T L+L N +LP D M
Sbjct: 311 VEAL--PSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGD-M 367
Query: 281 PKLTIVKLSGN 291
KL ++ LS N
Sbjct: 368 QKLKVINLSDN 378
Score = 43.6 bits (98), Expect = 0.008
Identities = 32/126 (25%), Positives = 64/126 (50%), Gaps = 6/126 (4%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I SL N+ TL++ N L + ++ + +D S N + LP +
Sbjct: 263 NSLQQLPETI-GSLKNITTLKIDENQLMYLP-DSIGGLISVEELDCSFNEVEALPSSI-G 319
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLY-SLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
T L T +N + +P + +G + ++ +L L NK++ + ++ L+++ LSD
Sbjct: 320 QLTNLRTFAADHNYLQQLPPE--IGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSD 377
Query: 123 NKINNI 128
N++ N+
Sbjct: 378 NRLKNL 383
>AF276423-1|AAK69431.1| 1412|Homo sapiens densin-180-like protein
protein.
Length = 1412
Score = 81.4 bits (192), Expect = 3e-14
Identities = 74/270 (27%), Positives = 114/270 (42%), Gaps = 9/270 (3%)
Query: 22 TLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYV 81
TL LE++ E FT K L + L N + LP++LF N L + + +N + +
Sbjct: 26 TLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTL 84
Query: 82 PSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXX 141
P+ S L +L+ LD+SKN IQ + K L I++ S N I+ + D F
Sbjct: 85 PA-SIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPD-GFSQLLNLTQ 142
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
+ L+ +P F L L L+L N L L L L LDL N +++P
Sbjct: 143 LYLNDAFLEFLPAN-FGRLTKLQILELRENQLKMLPKT-MNRLTQLERLDLGSNEFTEVP 200
Query: 202 DNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT 261
+ L++ + N+L F I F G E+ + S +NL
Sbjct: 201 E-VLEQLSGLKEFWMDANRLTF--IPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQD 257
Query: 262 LYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L L N LP T+ + +T +K+ N
Sbjct: 258 LLLSSNSLQQLP-ETIGSLKNITTLKIDEN 286
Score = 73.7 bits (173), Expect = 6e-12
Identities = 74/268 (27%), Positives = 112/268 (41%), Gaps = 9/268 (3%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
+E +P IF L+ L L N +EE+ + F + + L + L +N L TLP + AN
Sbjct: 34 LEQVPKEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTLPASI-ANL 91
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKI 125
L +D+S N + P ++ L I++ S N I + +G L NL L L+D +
Sbjct: 92 INLRELDVSKNGIQEFP-ENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFL 150
Query: 126 NNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
+ N F N+LK +P + N L L LDL +N + V E L
Sbjct: 151 EFLPAN-FGRLTKLQILELRENQLKMLPKTM-NRLTQLERLDLGSNEFTEVPEV-LEQLS 207
Query: 186 LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXX 245
L+ + N L+ IP L LD+SKN + +
Sbjct: 208 GLKEFWMDANRLTFIP-GFIGSLKQLTYLDVSKNNIEMVE--EGISTCENLQDLLLSSNS 264
Query: 246 YEVHFKAFSMLKNLTTLYLDGNMFPSLP 273
+ + LKN+TTL +D N LP
Sbjct: 265 LQQLPETIGSLKNITTLKIDENQLMYLP 292
Score = 72.5 bits (170), Expect = 1e-11
Identities = 81/311 (26%), Positives = 136/311 (43%), Gaps = 32/311 (10%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + LP I +L+NL+ L + +N ++E E + K L V+ S N + LP+ F
Sbjct: 78 DNDLTTLPASI-ANLINLRELDVSKNGIQEFP-ENIKNCKVLTIVEASVNPISKLPDG-F 134
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
+ L + +++ + ++P++ F L LQIL+L +N+++ + L L+ L L
Sbjct: 135 SQLLNLTQLYLNDAFLEFLPAN-FGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGS 193
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL-MSLAGVE- 180
N+ + + E D N+L IP +LK L +LD+S NN+ M G+
Sbjct: 194 NEFTEVPE-VLEQLSGLKEFWMDANRLTFIPG-FIGSLKQLTYLDVSKNNIEMVEEGIST 251
Query: 181 --------------------FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
SLK + L + EN L +PD+ ++E+LD S N+
Sbjct: 252 CENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDS-IGGLISVEELDCSFNE 310
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ + + G + KN+T L+L N +LP D M
Sbjct: 311 VEAL--PSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGD-M 367
Query: 281 PKLTIVKLSGN 291
KL ++ LS N
Sbjct: 368 QKLKVINLSDN 378
Score = 43.6 bits (98), Expect = 0.008
Identities = 32/126 (25%), Positives = 64/126 (50%), Gaps = 6/126 (4%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I SL N+ TL++ N L + ++ + +D S N + LP +
Sbjct: 263 NSLQQLPETI-GSLKNITTLKIDENQLMYLP-DSIGGLISVEELDCSFNEVEALPSSI-G 319
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLY-SLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
T L T +N + +P + +G + ++ +L L NK++ + ++ L+++ LSD
Sbjct: 320 QLTNLRTFAADHNYLQQLPPE--IGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSD 377
Query: 123 NKINNI 128
N++ N+
Sbjct: 378 NRLKNL 383
>AF263744-1|AAF77048.1| 1371|Homo sapiens erbb2-interacting protein
ERBIN protein.
Length = 1371
Score = 81.4 bits (192), Expect = 3e-14
Identities = 74/270 (27%), Positives = 114/270 (42%), Gaps = 9/270 (3%)
Query: 22 TLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYV 81
TL LE++ E FT K L + L N + LP++LF N L + + +N + +
Sbjct: 26 TLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTL 84
Query: 82 PSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXX 141
P+ S L +L+ LD+SKN IQ + K L I++ S N I+ + D F
Sbjct: 85 PA-SIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPD-GFSQLLNLTQ 142
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
+ L+ +P F L L L+L N L L L L LDL N +++P
Sbjct: 143 LYLNDAFLEFLPAN-FGRLTKLQILELRENQLKMLPKT-MNRLTQLERLDLGSNEFTEVP 200
Query: 202 DNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT 261
+ L++ + N+L F I F G E+ + S +NL
Sbjct: 201 E-VLEQLSGLKEFWMDANRLTF--IPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQD 257
Query: 262 LYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L L N LP T+ + +T +K+ N
Sbjct: 258 LLLSSNSLQQLP-ETIGSLKNITTLKIDEN 286
Score = 73.7 bits (173), Expect = 6e-12
Identities = 74/268 (27%), Positives = 112/268 (41%), Gaps = 9/268 (3%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
+E +P IF L+ L L N +EE+ + F + + L + L +N L TLP + AN
Sbjct: 34 LEQVPKEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTLPASI-ANL 91
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKI 125
L +D+S N + P ++ L I++ S N I + +G L NL L L+D +
Sbjct: 92 INLRELDVSKNGIQEFP-ENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFL 150
Query: 126 NNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
+ N F N+LK +P + N L L LDL +N + V E L
Sbjct: 151 EFLPAN-FGRLTKLQILELRENQLKMLPKTM-NRLTQLERLDLGSNEFTEVPEV-LEQLS 207
Query: 186 LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXX 245
L+ + N L+ IP L LD+SKN + +
Sbjct: 208 GLKEFWMDANRLTFIP-GFIGSLKQLTYLDVSKNNIEMVE--EGISTCENLQDLLLSSNS 264
Query: 246 YEVHFKAFSMLKNLTTLYLDGNMFPSLP 273
+ + LKN+TTL +D N LP
Sbjct: 265 LQQLPETIGSLKNITTLKIDENQLMYLP 292
Score = 72.5 bits (170), Expect = 1e-11
Identities = 81/311 (26%), Positives = 136/311 (43%), Gaps = 32/311 (10%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + LP I +L+NL+ L + +N ++E E + K L V+ S N + LP+ F
Sbjct: 78 DNDLTTLPASI-ANLINLRELDVSKNGIQEFP-ENIKNCKVLTIVEASVNPISKLPDG-F 134
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
+ L + +++ + ++P++ F L LQIL+L +N+++ + L L+ L L
Sbjct: 135 SQLLNLTQLYLNDAFLEFLPAN-FGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGS 193
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL-MSLAGVE- 180
N+ + + E D N+L IP +LK L +LD+S NN+ M G+
Sbjct: 194 NEFTEVPE-VLEQLSGLKEFWMDANRLTFIPG-FIGSLKQLTYLDVSKNNIEMVEEGIST 251
Query: 181 --------------------FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
SLK + L + EN L +PD+ ++E+LD S N+
Sbjct: 252 CENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDS-IGGLISVEELDCSFNE 310
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ + + G + KN+T L+L N +LP D M
Sbjct: 311 VEAL--PSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGD-M 367
Query: 281 PKLTIVKLSGN 291
KL ++ LS N
Sbjct: 368 QKLKVINLSDN 378
Score = 43.6 bits (98), Expect = 0.008
Identities = 32/126 (25%), Positives = 64/126 (50%), Gaps = 6/126 (4%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I SL N+ TL++ N L + ++ + +D S N + LP +
Sbjct: 263 NSLQQLPETI-GSLKNITTLKIDENQLMYLP-DSIGGLISVEELDCSFNEVEALPSSI-G 319
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLY-SLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
T L T +N + +P + +G + ++ +L L NK++ + ++ L+++ LSD
Sbjct: 320 QLTNLRTFAADHNYLQQLPPE--IGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSD 377
Query: 123 NKINNI 128
N++ N+
Sbjct: 378 NRLKNL 383
>AB033051-1|BAA86539.2| 1371|Homo sapiens KIAA1225 protein protein.
Length = 1371
Score = 81.4 bits (192), Expect = 3e-14
Identities = 74/270 (27%), Positives = 114/270 (42%), Gaps = 9/270 (3%)
Query: 22 TLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYV 81
TL LE++ E FT K L + L N + LP++LF N L + + +N + +
Sbjct: 26 TLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTL 84
Query: 82 PSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXX 141
P+ S L +L+ LD+SKN IQ + K L I++ S N I+ + D F
Sbjct: 85 PA-SIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPD-GFSQLLNLTQ 142
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
+ L+ +P F L L L+L N L L L L LDL N +++P
Sbjct: 143 LYLNDAFLEFLPAN-FGRLTKLQILELRENQLKMLPKT-MNRLTQLERLDLGSNEFTEVP 200
Query: 202 DNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT 261
+ L++ + N+L F I F G E+ + S +NL
Sbjct: 201 E-VLEQLSGLKEFWMDANRLTF--IPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQD 257
Query: 262 LYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L L N LP T+ + +T +K+ N
Sbjct: 258 LLLSSNSLQQLP-ETIGSLKNITTLKIDEN 286
Score = 73.7 bits (173), Expect = 6e-12
Identities = 74/268 (27%), Positives = 112/268 (41%), Gaps = 9/268 (3%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
+E +P IF L+ L L N +EE+ + F + + L + L +N L TLP + AN
Sbjct: 34 LEQVPKEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTLPASI-ANL 91
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKI 125
L +D+S N + P ++ L I++ S N I + +G L NL L L+D +
Sbjct: 92 INLRELDVSKNGIQEFP-ENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFL 150
Query: 126 NNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
+ N F N+LK +P + N L L LDL +N + V E L
Sbjct: 151 EFLPAN-FGRLTKLQILELRENQLKMLPKTM-NRLTQLERLDLGSNEFTEVPEV-LEQLS 207
Query: 186 LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXX 245
L+ + N L+ IP L LD+SKN + +
Sbjct: 208 GLKEFWMDANRLTFIP-GFIGSLKQLTYLDVSKNNIEMVE--EGISTCENLQDLLLSSNS 264
Query: 246 YEVHFKAFSMLKNLTTLYLDGNMFPSLP 273
+ + LKN+TTL +D N LP
Sbjct: 265 LQQLPETIGSLKNITTLKIDENQLMYLP 292
Score = 72.5 bits (170), Expect = 1e-11
Identities = 81/311 (26%), Positives = 136/311 (43%), Gaps = 32/311 (10%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + LP I +L+NL+ L + +N ++E E + K L V+ S N + LP+ F
Sbjct: 78 DNDLTTLPASI-ANLINLRELDVSKNGIQEFP-ENIKNCKVLTIVEASVNPISKLPDG-F 134
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
+ L + +++ + ++P++ F L LQIL+L +N+++ + L L+ L L
Sbjct: 135 SQLLNLTQLYLNDAFLEFLPAN-FGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGS 193
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL-MSLAGVE- 180
N+ + + E D N+L IP +LK L +LD+S NN+ M G+
Sbjct: 194 NEFTEVPE-VLEQLSGLKEFWMDANRLTFIPG-FIGSLKQLTYLDVSKNNIEMVEEGIST 251
Query: 181 --------------------FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
SLK + L + EN L +PD+ ++E+LD S N+
Sbjct: 252 CENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDS-IGGLISVEELDCSFNE 310
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ + + G + KN+T L+L N +LP D M
Sbjct: 311 VEAL--PSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGD-M 367
Query: 281 PKLTIVKLSGN 291
KL ++ LS N
Sbjct: 368 QKLKVINLSDN 378
Score = 43.6 bits (98), Expect = 0.008
Identities = 32/126 (25%), Positives = 64/126 (50%), Gaps = 6/126 (4%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I SL N+ TL++ N L + ++ + +D S N + LP +
Sbjct: 263 NSLQQLPETI-GSLKNITTLKIDENQLMYLP-DSIGGLISVEELDCSFNEVEALPSSI-G 319
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLY-SLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
T L T +N + +P + +G + ++ +L L NK++ + ++ L+++ LSD
Sbjct: 320 QLTNLRTFAADHNYLQQLPPE--IGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSD 377
Query: 123 NKINNI 128
N++ N+
Sbjct: 378 NRLKNL 383
>AC108017-1|AAY41039.1| 260|Homo sapiens unknown protein.
Length = 260
Score = 80.6 bits (190), Expect = 6e-14
Identities = 53/177 (29%), Positives = 89/177 (50%), Gaps = 2/177 (1%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+ L N + LP F N L+ + + NN++ + +F GL SL L LS N+I ++
Sbjct: 68 MSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLK 127
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQ-LFNNLKCLI 164
G F L L+ L + DN ++ IS F N L +P + L ++ L
Sbjct: 128 PGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLH 187
Query: 165 FLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
+LDL N++ +L + F S L L +++N ++ + +NTF+ L++LDL NK+
Sbjct: 188 WLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKI 244
Score = 65.7 bits (153), Expect = 2e-09
Identities = 51/186 (27%), Positives = 86/186 (46%), Gaps = 2/186 (1%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + LP F++ +L+ L LQ N + I AF L + LS+N + L +F
Sbjct: 73 NLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFE 132
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF--SLKNLQILKLS 121
+ LE + I +N + + +F GL SL +L L N + + + + L L L
Sbjct: 133 DLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLE 192
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
N I+N+ + F + +NK+ ++ F L+ L LDL +N + +L + F
Sbjct: 193 GNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIF 252
Query: 182 ESLKLL 187
+ LK L
Sbjct: 253 KDLKEL 258
Score = 60.1 bits (139), Expect = 8e-08
Identities = 46/197 (23%), Positives = 84/197 (42%), Gaps = 2/197 (1%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRV 78
N+ + LQ N + ++ + F + L + L NN + ++ F L + +S+NR+
Sbjct: 64 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 123
Query: 79 VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAF-ENX 136
++ F L+ L+ L + N + I TF L +L +L L +N + + D ++
Sbjct: 124 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 183
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
+ N + N+ F + L L + N + L F L+ L LDL N
Sbjct: 184 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNK 243
Query: 197 LSQIPDNTFSDCFNLEK 213
+ +P F D L +
Sbjct: 244 IENLPPLIFKDLKELSQ 260
Score = 47.6 bits (108), Expect = 5e-04
Identities = 38/146 (26%), Positives = 57/146 (39%), Gaps = 1/146 (0%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N ++ +P F N L L L NN + S++ F L L L L N ++ + F
Sbjct: 73 NLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFE 132
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSM-LKNLTTLYLD 265
D LE L + N L I+ FYG + K + L L L+
Sbjct: 133 DLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLE 192
Query: 266 GNMFPSLPSRTLDYMPKLTIVKLSGN 291
GN +L + T LT++ + N
Sbjct: 193 GNHIHNLRNLTFISCSNLTVLVMRKN 218
Score = 45.2 bits (102), Expect = 0.003
Identities = 46/179 (25%), Positives = 66/179 (36%), Gaps = 1/179 (0%)
Query: 114 NLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
N+ + L N I + + F+N NK+ +I F L L L LS+N +
Sbjct: 64 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 123
Query: 174 MSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL-RFINITAFYGX 232
L FE L L L +++N LS+I TF +L L L N L R +
Sbjct: 124 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 183
Query: 233 XXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + F NLT L + N L T + KL + L N
Sbjct: 184 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSN 242
>Z93015-1|CAI42364.1| 481|Homo sapiens nyctalopin protein.
Length = 481
Score = 80.2 bits (189), Expect = 7e-14
Identities = 84/334 (25%), Positives = 135/334 (40%), Gaps = 28/334 (8%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNY-LYTLPEKLF 62
N + +L F +L +L+ L L+ N L I AF +L + L++N L L + F
Sbjct: 72 NGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTF 131
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
A + L +D++ R+ VP L +L+ L N + + L NL L
Sbjct: 132 AALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLANLTHAHLER 191
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
+I ++ ++ + N+++ + F + L L L++N L L F
Sbjct: 192 GRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFR 251
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L+ LR L+L NAL ++ F+D LE L L +N + F
Sbjct: 252 GLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAF------------------- 292
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYI 302
V AF L L L+L+GN L L + L NPW CDC ++
Sbjct: 293 -----VEEGAFQNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRNPWCCDCRLEWL 347
Query: 303 SAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKF 336
W+ ++ D C SP + G L ++ F
Sbjct: 348 RDWME-GSGRVTDV--PCASPGSVAGLDLSQVTF 378
Score = 47.6 bits (108), Expect = 5e-04
Identities = 46/199 (23%), Positives = 78/199 (39%), Gaps = 3/199 (1%)
Query: 95 LDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRN-KLKNI 152
+DL +N ++ + F +L +L+ L L N ++ I+ AF+ N L+ +
Sbjct: 67 IDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYL 126
Query: 153 PTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLE 212
+ F L L LDL+ L S+ L LR L +N ++P NL
Sbjct: 127 HARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVP-GALRGLANLT 185
Query: 213 KLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSL 272
L + ++ + ++ G VH AF L L L+ N+ L
Sbjct: 186 HAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAEL 245
Query: 273 PSRTLDYMPKLTIVKLSGN 291
P+ + +L + L GN
Sbjct: 246 PADAFRGLRRLRTLNLGGN 264
Score = 35.9 bits (79), Expect = 1.6
Identities = 27/98 (27%), Positives = 44/98 (44%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + LP F L L+TL L N L+ + F +L + L N + + E F
Sbjct: 239 DNLLAELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAF 298
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKN 100
N + L + ++ NR+ + +F + L L L +N
Sbjct: 299 QNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRN 336
>BC112242-1|AAI12243.1| 481|Homo sapiens nyctalopin protein.
Length = 481
Score = 80.2 bits (189), Expect = 7e-14
Identities = 84/334 (25%), Positives = 135/334 (40%), Gaps = 28/334 (8%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNY-LYTLPEKLF 62
N + +L F +L +L+ L L+ N L I AF +L + L++N L L + F
Sbjct: 72 NGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTF 131
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
A + L +D++ R+ VP L +L+ L N + + L NL L
Sbjct: 132 AALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLANLTHAHLER 191
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
+I ++ ++ + N+++ + F + L L L++N L L F
Sbjct: 192 GRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFR 251
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L+ LR L+L NAL ++ F+D LE L L +N + F
Sbjct: 252 GLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAF------------------- 292
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYI 302
V AF L L L+L+GN L L + L NPW CDC ++
Sbjct: 293 -----VEEGAFQNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRNPWCCDCRLEWL 347
Query: 303 SAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKF 336
W+ ++ D C SP + G L ++ F
Sbjct: 348 RDWME-GSGRVTDV--PCASPGSVAGLDLSQVTF 378
Score = 47.6 bits (108), Expect = 5e-04
Identities = 46/199 (23%), Positives = 78/199 (39%), Gaps = 3/199 (1%)
Query: 95 LDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRN-KLKNI 152
+DL +N ++ + F +L +L+ L L N ++ I+ AF+ N L+ +
Sbjct: 67 IDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYL 126
Query: 153 PTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLE 212
+ F L L LDL+ L S+ L LR L +N ++P NL
Sbjct: 127 HARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVP-GALRGLANLT 185
Query: 213 KLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSL 272
L + ++ + ++ G VH AF L L L+ N+ L
Sbjct: 186 HAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAEL 245
Query: 273 PSRTLDYMPKLTIVKLSGN 291
P+ + +L + L GN
Sbjct: 246 PADAFRGLRRLRTLNLGGN 264
Score = 35.9 bits (79), Expect = 1.6
Identities = 27/98 (27%), Positives = 44/98 (44%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + LP F L L+TL L N L+ + F +L + L N + + E F
Sbjct: 239 DNLLAELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAF 298
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKN 100
N + L + ++ NR+ + +F + L L L +N
Sbjct: 299 QNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRN 336
>AJ278865-1|CAC19014.1| 481|Homo sapiens leucine-rich repeat
protein protein.
Length = 481
Score = 80.2 bits (189), Expect = 7e-14
Identities = 84/334 (25%), Positives = 135/334 (40%), Gaps = 28/334 (8%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNY-LYTLPEKLF 62
N + +L F +L +L+ L L+ N L I AF +L + L++N L L + F
Sbjct: 72 NGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTF 131
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
A + L +D++ R+ VP L +L+ L N + + L NL L
Sbjct: 132 AALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLANLTHAHLER 191
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
+I ++ ++ + N+++ + F + L L L++N L L F
Sbjct: 192 GRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFR 251
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L+ LR L+L NAL ++ F+D LE L L +N + F
Sbjct: 252 GLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAF------------------- 292
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYI 302
V AF L L L+L+GN L L + L NPW CDC ++
Sbjct: 293 -----VEEGAFQNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRNPWCCDCRLEWL 347
Query: 303 SAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKF 336
W+ ++ D C SP + G L ++ F
Sbjct: 348 RDWME-GSGRVTDV--PCASPGSVAGLDLSQVTF 378
Score = 47.6 bits (108), Expect = 5e-04
Identities = 46/199 (23%), Positives = 78/199 (39%), Gaps = 3/199 (1%)
Query: 95 LDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRN-KLKNI 152
+DL +N ++ + F +L +L+ L L N ++ I+ AF+ N L+ +
Sbjct: 67 IDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYL 126
Query: 153 PTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLE 212
+ F L L LDL+ L S+ L LR L +N ++P NL
Sbjct: 127 HARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVP-GALRGLANLT 185
Query: 213 KLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSL 272
L + ++ + ++ G VH AF L L L+ N+ L
Sbjct: 186 HAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAEL 245
Query: 273 PSRTLDYMPKLTIVKLSGN 291
P+ + +L + L GN
Sbjct: 246 PADAFRGLRRLRTLNLGGN 264
Score = 35.9 bits (79), Expect = 1.6
Identities = 27/98 (27%), Positives = 44/98 (44%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + LP F L L+TL L N L+ + F +L + L N + + E F
Sbjct: 239 DNLLAELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAF 298
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKN 100
N + L + ++ NR+ + +F + L L L +N
Sbjct: 299 QNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRN 336
>AF254868-1|AAG42685.1| 481|Homo sapiens nyctalopin protein.
Length = 481
Score = 80.2 bits (189), Expect = 7e-14
Identities = 84/334 (25%), Positives = 135/334 (40%), Gaps = 28/334 (8%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNY-LYTLPEKLF 62
N + +L F +L +L+ L L+ N L I AF +L + L++N L L + F
Sbjct: 72 NGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTF 131
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
A + L +D++ R+ VP L +L+ L N + + L NL L
Sbjct: 132 AALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLANLTHAHLER 191
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
+I ++ ++ + N+++ + F + L L L++N L L F
Sbjct: 192 GRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFR 251
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXX 242
L+ LR L+L NAL ++ F+D LE L L +N + F
Sbjct: 252 GLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAF------------------- 292
Query: 243 XXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYI 302
V AF L L L+L+GN L L + L NPW CDC ++
Sbjct: 293 -----VEEGAFQNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRNPWCCDCRLEWL 347
Query: 303 SAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKF 336
W+ ++ D C SP + G L ++ F
Sbjct: 348 RDWME-GSGRVTDV--PCASPGSVAGLDLSQVTF 378
Score = 47.6 bits (108), Expect = 5e-04
Identities = 46/199 (23%), Positives = 78/199 (39%), Gaps = 3/199 (1%)
Query: 95 LDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRN-KLKNI 152
+DL +N ++ + F +L +L+ L L N ++ I+ AF+ N L+ +
Sbjct: 67 IDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYL 126
Query: 153 PTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLE 212
+ F L L LDL+ L S+ L LR L +N ++P NL
Sbjct: 127 HARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVP-GALRGLANLT 185
Query: 213 KLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSL 272
L + ++ + ++ G VH AF L L L+ N+ L
Sbjct: 186 HAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAEL 245
Query: 273 PSRTLDYMPKLTIVKLSGN 291
P+ + +L + L GN
Sbjct: 246 PADAFRGLRRLRTLNLGGN 264
Score = 35.9 bits (79), Expect = 1.6
Identities = 27/98 (27%), Positives = 44/98 (44%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + LP F L L+TL L N L+ + F +L + L N + + E F
Sbjct: 239 DNLLAELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAF 298
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKN 100
N + L + ++ NR+ + +F + L L L +N
Sbjct: 299 QNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRN 336
>BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 79.8 bits (188), Expect = 1e-13
Identities = 66/221 (29%), Positives = 114/221 (51%), Gaps = 9/221 (4%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I +L NLK L LQ N L I SE F L +DLSNN+L T+P F+
Sbjct: 138 NKLKILPEEI-TNLRNLKCLYLQHNELTCI-SEGFEQLSNLEDLDLSNNHLTTVPAS-FS 194
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
+ + L +++S+N + +P++ + L+ LD + N ++ I +++L++L L N
Sbjct: 195 SLSSLVRLNLSSNELKSLPAE-INRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRN 253
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFES 183
K+ + + F + N+++ + + +L ++ LDL +N L S+ E
Sbjct: 254 KLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPD-EIIL 310
Query: 184 LKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L+ L LDL N +S +P + + +L+ L L N LR I
Sbjct: 311 LRSLERLDLSNNDISSLPYSLGN--LHLKFLALEGNPLRTI 349
Score = 65.7 bits (153), Expect = 2e-09
Identities = 56/225 (24%), Positives = 107/225 (47%), Gaps = 13/225 (5%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + +LP F S LK L + N +E +++E + +DL +N L ++P+++
Sbjct: 253 NKLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIIL 310
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
+ LE +D+SNN + +P LG L+ L L N ++ I+ S ++LK +
Sbjct: 311 LRS-LERLDLSNNDISSLPYS--LGNLHLKFLALEGNPLRTIRREIISKGTQEVLKYLRS 367
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFES 183
KI + + E+ +++ NI + + L LD S+ + F++
Sbjct: 368 KIKDDGPSQSESATETAMTLPSESRV-NI-----HAIITLKILDYSDKQATLIPDEVFDA 421
Query: 184 LK--LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINI 226
+K ++ +++ +N L +IP + +DLS NKL FI++
Sbjct: 422 VKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISL 466
Score = 60.9 bits (141), Expect = 5e-08
Identities = 56/181 (30%), Positives = 85/181 (46%), Gaps = 26/181 (14%)
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNK- 124
T L + ISNN++ + D L L +L +LD+ N++ ++ + L+NLQ L +S NK
Sbjct: 82 TDLTKLIISNNKLQSLTDDLRL-LPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKL 140
Query: 125 ------INNISD---------------NAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCL 163
I N+ + FE N L +P F++L L
Sbjct: 141 KILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPAS-FSSLSSL 199
Query: 164 IFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRF 223
+ L+LS+N L SL E +K L++LD N L IP + +LE L L +NKLRF
Sbjct: 200 VRLNLSSNELKSLP-AEINRMKRLKHLDCNSNLLETIPPE-LAGMESLELLYLRRNKLRF 257
Query: 224 I 224
+
Sbjct: 258 L 258
Score = 60.5 bits (140), Expect = 6e-08
Identities = 79/337 (23%), Positives = 136/337 (40%), Gaps = 28/337 (8%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N +E L + L ++ L L+ N L+ + E + L +DLSNN + +LP L
Sbjct: 274 ENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIIL-LRSLERLDLSNNDISSLPYSL- 331
Query: 63 ANNTFLETIDISNN-------RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKN- 114
N L+ + + N ++ + L +I D ++ ++ +L +
Sbjct: 332 -GNLHLKFLALEGNPLRTIRREIISKGTQEVLKYLRSKIKDDGPSQSESATETAMTLPSE 390
Query: 115 ----------LQILKLSDNKINNISDNAFE--NXXXXXXXXXDRNKLKNIPTQLFNNLKC 162
L+IL SD + I D F+ +N+L IP ++ +
Sbjct: 391 SRVNIHAIITLKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEM 450
Query: 163 LIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
+ +DLS N L S +E L+ L LDL+ N L+ +P+ S L+ ++LS N+ +
Sbjct: 451 VSDVDLSFNKL-SFISLELCVLQKLTFLDLRNNFLNSLPEEMES-LVRLQTINLSFNRFK 508
Query: 223 FINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPK 282
+ Y V + M++NLTTL L N +P L
Sbjct: 509 MLP-EVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPE-LGNCVN 566
Query: 283 LTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPT 319
L + L GNP+ A+ + + E + D PT
Sbjct: 567 LRTLLLDGNPFRVPRAAILMKGTAAILEY-LRDRIPT 602
>BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein.
Length = 581
Score = 79.8 bits (188), Expect = 1e-13
Identities = 66/221 (29%), Positives = 114/221 (51%), Gaps = 9/221 (4%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I +L NLK L LQ N L I SE F L +DLSNN+L T+P F+
Sbjct: 117 NKLKILPEEI-TNLRNLKCLYLQHNELTCI-SEGFEQLSNLEDLDLSNNHLTTVPAS-FS 173
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
+ + L +++S+N + +P++ + L+ LD + N ++ I +++L++L L N
Sbjct: 174 SLSSLVRLNLSSNELKSLPAE-INRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRN 232
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFES 183
K+ + + F + N+++ + + +L ++ LDL +N L S+ E
Sbjct: 233 KLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPD-EIIL 289
Query: 184 LKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L+ L LDL N +S +P + + +L+ L L N LR I
Sbjct: 290 LRSLERLDLSNNDISSLPYSLGN--LHLKFLALEGNPLRTI 328
Score = 65.7 bits (153), Expect = 2e-09
Identities = 56/225 (24%), Positives = 107/225 (47%), Gaps = 13/225 (5%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + +LP F S LK L + N +E +++E + +DL +N L ++P+++
Sbjct: 232 NKLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIIL 289
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
+ LE +D+SNN + +P LG L+ L L N ++ I+ S ++LK +
Sbjct: 290 LRS-LERLDLSNNDISSLPYS--LGNLHLKFLALEGNPLRTIRREIISKGTQEVLKYLRS 346
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFES 183
KI + + E+ +++ NI + + L LD S+ + F++
Sbjct: 347 KIKDDGPSQSESATETAMTLPSESRV-NI-----HAIITLKILDYSDKQATLIPDEVFDA 400
Query: 184 LK--LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINI 226
+K ++ +++ +N L +IP + +DLS NKL FI++
Sbjct: 401 VKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISL 445
Score = 60.9 bits (141), Expect = 5e-08
Identities = 56/181 (30%), Positives = 85/181 (46%), Gaps = 26/181 (14%)
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNK- 124
T L + ISNN++ + D L L +L +LD+ N++ ++ + L+NLQ L +S NK
Sbjct: 61 TDLTKLIISNNKLQSLTDDLRL-LPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKL 119
Query: 125 ------INNISD---------------NAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCL 163
I N+ + FE N L +P F++L L
Sbjct: 120 KILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPAS-FSSLSSL 178
Query: 164 IFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRF 223
+ L+LS+N L SL E +K L++LD N L IP + +LE L L +NKLRF
Sbjct: 179 VRLNLSSNELKSLP-AEINRMKRLKHLDCNSNLLETIPPE-LAGMESLELLYLRRNKLRF 236
Query: 224 I 224
+
Sbjct: 237 L 237
Score = 60.5 bits (140), Expect = 6e-08
Identities = 79/337 (23%), Positives = 136/337 (40%), Gaps = 28/337 (8%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N +E L + L ++ L L+ N L+ + E + L +DLSNN + +LP L
Sbjct: 253 ENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIIL-LRSLERLDLSNNDISSLPYSL- 310
Query: 63 ANNTFLETIDISNN-------RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKN- 114
N L+ + + N ++ + L +I D ++ ++ +L +
Sbjct: 311 -GNLHLKFLALEGNPLRTIRREIISKGTQEVLKYLRSKIKDDGPSQSESATETAMTLPSE 369
Query: 115 ----------LQILKLSDNKINNISDNAFE--NXXXXXXXXXDRNKLKNIPTQLFNNLKC 162
L+IL SD + I D F+ +N+L IP ++ +
Sbjct: 370 SRVNIHAIITLKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEM 429
Query: 163 LIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
+ +DLS N L S +E L+ L LDL+ N L+ +P+ S L+ ++LS N+ +
Sbjct: 430 VSDVDLSFNKL-SFISLELCVLQKLTFLDLRNNFLNSLPEEMES-LVRLQTINLSFNRFK 487
Query: 223 FINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPK 282
+ Y V + M++NLTTL L N +P L
Sbjct: 488 MLP-EVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPE-LGNCVN 545
Query: 283 LTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPT 319
L + L GNP+ A+ + + E + D PT
Sbjct: 546 LRTLLLDGNPFRVPRAAILMKGTAAILEY-LRDRIPT 581
>AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 79.8 bits (188), Expect = 1e-13
Identities = 66/221 (29%), Positives = 114/221 (51%), Gaps = 9/221 (4%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I +L NLK L LQ N L I SE F L +DLSNN+L T+P F+
Sbjct: 138 NKLKILPEEI-TNLRNLKCLYLQHNELTCI-SEGFEQLSNLEDLDLSNNHLTTVPAS-FS 194
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
+ + L +++S+N + +P++ + L+ LD + N ++ I +++L++L L N
Sbjct: 195 SLSSLVRLNLSSNELKSLPAE-INRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRN 253
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFES 183
K+ + + F + N+++ + + +L ++ LDL +N L S+ E
Sbjct: 254 KLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPD-EIIL 310
Query: 184 LKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L+ L LDL N +S +P + + +L+ L L N LR I
Sbjct: 311 LRSLERLDLSNNDISSLPYSLGN--LHLKFLALEGNPLRTI 349
Score = 65.7 bits (153), Expect = 2e-09
Identities = 56/225 (24%), Positives = 107/225 (47%), Gaps = 13/225 (5%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + +LP F S LK L + N +E +++E + +DL +N L ++P+++
Sbjct: 253 NKLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIIL 310
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
+ LE +D+SNN + +P LG L+ L L N ++ I+ S ++LK +
Sbjct: 311 LRS-LERLDLSNNDISSLPYS--LGNLHLKFLALEGNPLRTIRREIISKGTQEVLKYLRS 367
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFES 183
KI + + E+ +++ NI + + L LD S+ + F++
Sbjct: 368 KIKDDGPSQSESATETAMTLPSESRV-NI-----HAIITLKILDYSDKQATLIPDEVFDA 421
Query: 184 LK--LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINI 226
+K ++ +++ +N L +IP + +DLS NKL FI++
Sbjct: 422 VKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISL 466
Score = 60.9 bits (141), Expect = 5e-08
Identities = 56/181 (30%), Positives = 85/181 (46%), Gaps = 26/181 (14%)
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNK- 124
T L + ISNN++ + D L L +L +LD+ N++ ++ + L+NLQ L +S NK
Sbjct: 82 TDLTKLIISNNKLQSLTDDLRL-LPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKL 140
Query: 125 ------INNISD---------------NAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCL 163
I N+ + FE N L +P F++L L
Sbjct: 141 KILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPAS-FSSLSSL 199
Query: 164 IFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRF 223
+ L+LS+N L SL E +K L++LD N L IP + +LE L L +NKLRF
Sbjct: 200 VRLNLSSNELKSLP-AEINRMKRLKHLDCNSNLLETIPPE-LAGMESLELLYLRRNKLRF 257
Query: 224 I 224
+
Sbjct: 258 L 258
Score = 60.5 bits (140), Expect = 6e-08
Identities = 79/337 (23%), Positives = 136/337 (40%), Gaps = 28/337 (8%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N +E L + L ++ L L+ N L+ + E + L +DLSNN + +LP L
Sbjct: 274 ENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIIL-LRSLERLDLSNNDISSLPYSL- 331
Query: 63 ANNTFLETIDISNN-------RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKN- 114
N L+ + + N ++ + L +I D ++ ++ +L +
Sbjct: 332 -GNLHLKFLALEGNPLRTIRREIISKGTQEVLKYLRSKIKDDGPSQSESATETAMTLPSE 390
Query: 115 ----------LQILKLSDNKINNISDNAFE--NXXXXXXXXXDRNKLKNIPTQLFNNLKC 162
L+IL SD + I D F+ +N+L IP ++ +
Sbjct: 391 SRVNIHAIITLKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEM 450
Query: 163 LIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
+ +DLS N L S +E L+ L LDL+ N L+ +P+ S L+ ++LS N+ +
Sbjct: 451 VSDVDLSFNKL-SFISLELCVLQKLTFLDLRNNFLNSLPEEMES-LVRLQTINLSFNRFK 508
Query: 223 FINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPK 282
+ Y V + M++NLTTL L N +P L
Sbjct: 509 MLP-EVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPE-LGNCVN 566
Query: 283 LTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPT 319
L + L GNP+ A+ + + E + D PT
Sbjct: 567 LRTLLLDGNPFRVPRAAILMKGTAAILEY-LRDRIPT 602
>AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens
cDNA FLJ12889 fis, clone NT2RP2004098, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 602
Score = 79.8 bits (188), Expect = 1e-13
Identities = 66/221 (29%), Positives = 114/221 (51%), Gaps = 9/221 (4%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I +L NLK L LQ N L I SE F L +DLSNN+L T+P F+
Sbjct: 138 NKLKILPEEI-TNLRNLKCLYLQHNELTCI-SEGFEQLSNLEDLDLSNNHLTTVPAS-FS 194
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
+ + L +++S+N + +P++ + L+ LD + N ++ I +++L++L L N
Sbjct: 195 SLSSLVRLNLSSNELKSLPAE-INRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRN 253
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFES 183
K+ + + F + N+++ + + +L ++ LDL +N L S+ E
Sbjct: 254 KLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPD-EIIL 310
Query: 184 LKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L+ L LDL N +S +P + + +L+ L L N LR I
Sbjct: 311 LRSLERLDLSNNDISSLPYSLGN--LHLKFLALEGNPLRTI 349
Score = 65.7 bits (153), Expect = 2e-09
Identities = 56/225 (24%), Positives = 107/225 (47%), Gaps = 13/225 (5%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + +LP F S LK L + N +E +++E + +DL +N L ++P+++
Sbjct: 253 NKLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIIL 310
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
+ LE +D+SNN + +P LG L+ L L N ++ I+ S ++LK +
Sbjct: 311 LRS-LERLDLSNNDISSLPYS--LGNLHLKFLALEGNPLRTIRREIISKGTQEVLKYLRS 367
Query: 124 KINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFES 183
KI + + E+ +++ NI + + L LD S+ + F++
Sbjct: 368 KIKDDGPSQSESATETAMTLPSESRV-NI-----HAIITLKILDYSDKQATLIPDEVFDA 421
Query: 184 LK--LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINI 226
+K ++ +++ +N L +IP + +DLS NKL FI++
Sbjct: 422 VKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISL 466
Score = 60.9 bits (141), Expect = 5e-08
Identities = 56/181 (30%), Positives = 85/181 (46%), Gaps = 26/181 (14%)
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNK- 124
T L + ISNN++ + D L L +L +LD+ N++ ++ + L+NLQ L +S NK
Sbjct: 82 TDLTKLIISNNKLQSLTDDLRL-LPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKL 140
Query: 125 ------INNISD---------------NAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCL 163
I N+ + FE N L +P F++L L
Sbjct: 141 KILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPAS-FSSLSSL 199
Query: 164 IFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRF 223
+ L+LS+N L SL E +K L++LD N L IP + +LE L L +NKLRF
Sbjct: 200 VRLNLSSNELKSLP-AEINRMKRLKHLDCNSNLLETIPPE-LAGMESLELLYLRRNKLRF 257
Query: 224 I 224
+
Sbjct: 258 L 258
Score = 60.5 bits (140), Expect = 6e-08
Identities = 79/337 (23%), Positives = 136/337 (40%), Gaps = 28/337 (8%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N +E L + L ++ L L+ N L+ + E + L +DLSNN + +LP L
Sbjct: 274 ENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIIL-LRSLERLDLSNNDISSLPYSL- 331
Query: 63 ANNTFLETIDISNN-------RVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKN- 114
N L+ + + N ++ + L +I D ++ ++ +L +
Sbjct: 332 -GNLHLKFLALEGNPLRTIRREIISKGTQEVLKYLRSKIKDDGPSQSESATETAMTLPSE 390
Query: 115 ----------LQILKLSDNKINNISDNAFE--NXXXXXXXXXDRNKLKNIPTQLFNNLKC 162
L+IL SD + I D F+ +N+L IP ++ +
Sbjct: 391 SRVNIHAIITLKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEM 450
Query: 163 LIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
+ +DLS N L S +E L+ L LDL+ N L+ +P+ S L+ ++LS N+ +
Sbjct: 451 VSDVDLSFNKL-SFISLELCVLQKLTFLDLRNNFLNSLPEEMES-LVRLQTINLSFNRFK 508
Query: 223 FINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPK 282
+ Y V + M++NLTTL L N +P L
Sbjct: 509 MLP-EVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPE-LGNCVN 566
Query: 283 LTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPT 319
L + L GNP+ A+ + + E + D PT
Sbjct: 567 LRTLLLDGNPFRVPRAAILMKGTAAILEY-LRDRIPT 602
>X72913-1|CAA51418.1| 376|Homo sapiens fibromodulin protein.
Length = 376
Score = 79.4 bits (187), Expect = 1e-13
Identities = 63/232 (27%), Positives = 113/232 (48%), Gaps = 17/232 (7%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYL--EEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+N + + G+F++ L + L N + +++ + F+ + L + L +N L +P
Sbjct: 114 NNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGP 173
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKL 120
L + L + + +N++ VP+++ GL +L L L N+IQ + + L++L +L L
Sbjct: 174 LPRS---LRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLYLLDL 230
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMS--LAG 178
S N + + D + N + +P F L+++ LS+N+L + LA
Sbjct: 231 SYNHLRKVPDGL---PSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLAS 287
Query: 179 VEFESLKLLRNLDLKENALSQIPD-NTFSDCFNLEKLDLSKNKLRFINITAF 229
F S LL LDL N L +IP NT NLE L L N++ +I++F
Sbjct: 288 NTFNSSSLL-ELDLSYNQLQKIPPVNT-----NLENLYLQGNRINEFSISSF 333
Score = 50.0 bits (114), Expect = 9e-05
Identities = 46/191 (24%), Positives = 84/191 (43%), Gaps = 9/191 (4%)
Query: 103 QNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN--IPTQLFNNL 160
+N++ F ++ + +N+I +I + F+N N++ + + ++F+ L
Sbjct: 95 RNLKYLPFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKL 154
Query: 161 KCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
+ L L L +NNL + G SL R L L N +S++P+N NL L L N+
Sbjct: 155 RHLERLYLDHNNLTRMPGPLPRSL---RELHLDHNQISRVPNNALEGLENLTALYLQHNE 211
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
++ + ++ G +V S L+ L Y++ N ++P
Sbjct: 212 IQEVG-SSMRGLRSLYLLDLSYNHLRKVPDGLPSALEQL---YMEHNNVYTVPDSYFRGA 267
Query: 281 PKLTIVKLSGN 291
PKL V+LS N
Sbjct: 268 PKLLYVRLSHN 278
>BC115012-1|AAI15013.1| 1371|Homo sapiens erbb2 interacting protein
protein.
Length = 1371
Score = 79.0 bits (186), Expect = 2e-13
Identities = 73/270 (27%), Positives = 113/270 (41%), Gaps = 9/270 (3%)
Query: 22 TLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYV 81
TL LE++ E FT K L + L N + LP++LF N L + + +N + +
Sbjct: 26 TLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTL 84
Query: 82 PSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXX 141
P+ S L +L+ LD+SKN IQ + K L I++ S N I+ + D F
Sbjct: 85 PA-SIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPD-GFSQLLNLTQ 142
Query: 142 XXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIP 201
+ L+ +P F L L L+L N L L L L LDL N +++P
Sbjct: 143 LYLNDAFLEFLPAN-FGRLTKLQILELRENQLKMLPKT-MNRLTQLERLDLGSNEFTEVP 200
Query: 202 DNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTT 261
+ L++ + N+L F I F G E+ + S +NL
Sbjct: 201 E-VLEQLSGLKEFWMDANRLTF--IPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQD 257
Query: 262 LYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
L L N LP + + +T +K+ N
Sbjct: 258 LLLSSNSLQQLP-EPIGSLKNITTLKIDEN 286
Score = 73.3 bits (172), Expect = 8e-12
Identities = 74/268 (27%), Positives = 112/268 (41%), Gaps = 9/268 (3%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
+E +P IF L+ L L N +EE+ + F + + L + L +N L TLP + AN
Sbjct: 34 LEQVPKEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTLPASI-ANL 91
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKI 125
L +D+S N + P ++ L I++ S N I + +G L NL L L+D +
Sbjct: 92 INLRELDVSKNGIQEFP-ENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFL 150
Query: 126 NNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
+ N F N+LK +P + N L L LDL +N + V E L
Sbjct: 151 EFLPAN-FGRLTKLQILELRENQLKMLPKTM-NRLTQLERLDLGSNEFTEVPEV-LEQLS 207
Query: 186 LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXX 245
L+ + N L+ IP L LD+SKN + +
Sbjct: 208 GLKEFWMDANRLTFIP-GFIGSLKQLTYLDVSKNNIEMVE--EGISTCENLQDLLLSSNS 264
Query: 246 YEVHFKAFSMLKNLTTLYLDGNMFPSLP 273
+ + LKN+TTL +D N LP
Sbjct: 265 LQQLPEPIGSLKNITTLKIDENQLMYLP 292
Score = 72.5 bits (170), Expect = 1e-11
Identities = 81/311 (26%), Positives = 136/311 (43%), Gaps = 32/311 (10%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DN + LP I +L+NL+ L + +N ++E E + K L V+ S N + LP+ F
Sbjct: 78 DNDLTTLPASI-ANLINLRELDVSKNGIQEFP-ENIKNCKVLTIVEASVNPISKLPDG-F 134
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
+ L + +++ + ++P++ F L LQIL+L +N+++ + L L+ L L
Sbjct: 135 SQLLNLTQLYLNDAFLEFLPAN-FGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGS 193
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL-MSLAGVE- 180
N+ + + E D N+L IP +LK L +LD+S NN+ M G+
Sbjct: 194 NEFTEVPE-VLEQLSGLKEFWMDANRLTFIPG-FIGSLKQLTYLDVSKNNIEMVEEGIST 251
Query: 181 --------------------FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
SLK + L + EN L +PD+ ++E+LD S N+
Sbjct: 252 CENLQDLLLSSNSLQQLPEPIGSLKNITTLKIDENQLMYLPDS-IGGLISVEELDCSFNE 310
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ + + G + KN+T L+L N +LP D M
Sbjct: 311 VEAL--PSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGD-M 367
Query: 281 PKLTIVKLSGN 291
KL ++ LS N
Sbjct: 368 QKLKVINLSDN 378
Score = 43.6 bits (98), Expect = 0.008
Identities = 32/126 (25%), Positives = 64/126 (50%), Gaps = 6/126 (4%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I SL N+ TL++ N L + ++ + +D S N + LP +
Sbjct: 263 NSLQQLPEPI-GSLKNITTLKIDENQLMYLP-DSIGGLISVEELDCSFNEVEALPSSI-G 319
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLY-SLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
T L T +N + +P + +G + ++ +L L NK++ + ++ L+++ LSD
Sbjct: 320 QLTNLRTFAADHNYLQQLPPE--IGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSD 377
Query: 123 NKINNI 128
N++ N+
Sbjct: 378 NRLKNL 383
>BC018370-1|AAH18370.1| 674|Homo sapiens fibronectin leucine rich
transmembrane protein 1 protein.
Length = 674
Score = 79.0 bits (186), Expect = 2e-13
Identities = 63/249 (25%), Positives = 108/249 (43%), Gaps = 10/249 (4%)
Query: 91 SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS--DNAFENXXXXXXXXXDRN 147
SL+ L L N ++ I + + + L+ L L DN ++ +S ++AF + RN
Sbjct: 128 SLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRN 187
Query: 148 KLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALS--QIPDNTF 205
L +IP+ L + L+ L L +N + ++ F+ L LR L L N L+ +I D+TF
Sbjct: 188 HLSSIPSGLPHTLE---ELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTF 244
Query: 206 SDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLD 265
S NL +L L +N L + + + + ++ L L L
Sbjct: 245 SRLQNLTELSLVRNSLAAPPLNL--PSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLS 302
Query: 266 GNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWY 325
N +LP D + L + L NPW C C+ +++ WV+ + C P
Sbjct: 303 NNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQGPEK 362
Query: 326 LEGHFLKKL 334
+ G +K +
Sbjct: 363 VRGMAIKDI 371
Score = 66.9 bits (156), Expect = 7e-10
Identities = 64/198 (32%), Positives = 97/198 (48%), Gaps = 10/198 (5%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLE--EIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
DN+V + + L+ L L N + I+ +AF +K+L + LS N+L ++P
Sbjct: 136 DNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSG 195
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI--QNIQNGTFS-LKNLQI 117
L +T LE + + +NR+ +P +F GL SL+ L L N + Q I + TFS L+NL
Sbjct: 196 L--PHT-LEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTE 252
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
L L N + N + D N + +IP ++ L LDLSNNNL +L
Sbjct: 253 LSLVRNSLAAPPLN-LPSAHLQKLYLQD-NAISHIPYNTLAKMRELERLDLSNNNLTTLP 310
Query: 178 GVEFESLKLLRNLDLKEN 195
F+ L L L L+ N
Sbjct: 311 RGLFDDLGNLAQLLLRNN 328
>AY358308-1|AAQ88675.1| 674|Homo sapiens FLRT1 protein.
Length = 674
Score = 79.0 bits (186), Expect = 2e-13
Identities = 63/249 (25%), Positives = 108/249 (43%), Gaps = 10/249 (4%)
Query: 91 SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS--DNAFENXXXXXXXXXDRN 147
SL+ L L N ++ I + + + L+ L L DN ++ +S ++AF + RN
Sbjct: 128 SLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRN 187
Query: 148 KLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALS--QIPDNTF 205
L +IP+ L + L+ L L +N + ++ F+ L LR L L N L+ +I D+TF
Sbjct: 188 HLSSIPSGLPHTLE---ELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTF 244
Query: 206 SDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLD 265
S NL +L L +N L + + + + ++ L L L
Sbjct: 245 SRLQNLTELSLVRNSLAAPPLNL--PSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLS 302
Query: 266 GNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWY 325
N +LP D + L + L NPW C C+ +++ WV+ + C P
Sbjct: 303 NNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQGPEK 362
Query: 326 LEGHFLKKL 334
+ G +K +
Sbjct: 363 VRGMAIKDI 371
Score = 66.9 bits (156), Expect = 7e-10
Identities = 64/198 (32%), Positives = 97/198 (48%), Gaps = 10/198 (5%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLE--EIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
DN+V + + L+ L L N + I+ +AF +K+L + LS N+L ++P
Sbjct: 136 DNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSG 195
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI--QNIQNGTFS-LKNLQI 117
L +T LE + + +NR+ +P +F GL SL+ L L N + Q I + TFS L+NL
Sbjct: 196 L--PHT-LEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTE 252
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
L L N + N + D N + +IP ++ L LDLSNNNL +L
Sbjct: 253 LSLVRNSLAAPPLN-LPSAHLQKLYLQD-NAISHIPYNTLAKMRELERLDLSNNNLTTLP 310
Query: 178 GVEFESLKLLRNLDLKEN 195
F+ L L L L+ N
Sbjct: 311 RGLFDDLGNLAQLLLRNN 328
>AF169675-1|AAF28459.1| 674|Homo sapiens leucine-rich repeat
transmembrane protein FLRT1 protein.
Length = 674
Score = 79.0 bits (186), Expect = 2e-13
Identities = 63/249 (25%), Positives = 108/249 (43%), Gaps = 10/249 (4%)
Query: 91 SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS--DNAFENXXXXXXXXXDRN 147
SL+ L L N ++ I + + + L+ L L DN ++ +S ++AF + RN
Sbjct: 128 SLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRN 187
Query: 148 KLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALS--QIPDNTF 205
L +IP+ L + L+ L L +N + ++ F+ L LR L L N L+ +I D+TF
Sbjct: 188 HLSSIPSGLPHTLE---ELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTF 244
Query: 206 SDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLD 265
S NL +L L +N L + + + + ++ L L L
Sbjct: 245 SRLQNLTELSLVRNSLAAPPLNL--PSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLS 302
Query: 266 GNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWY 325
N +LP D + L + L NPW C C+ +++ WV+ + C P
Sbjct: 303 NNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQGPEK 362
Query: 326 LEGHFLKKL 334
+ G +K +
Sbjct: 363 VRGMAIKDI 371
Score = 66.9 bits (156), Expect = 7e-10
Identities = 64/198 (32%), Positives = 97/198 (48%), Gaps = 10/198 (5%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLE--EIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
DN+V + + L+ L L N + I+ +AF +K+L + LS N+L ++P
Sbjct: 136 DNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSG 195
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI--QNIQNGTFS-LKNLQI 117
L +T LE + + +NR+ +P +F GL SL+ L L N + Q I + TFS L+NL
Sbjct: 196 L--PHT-LEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTE 252
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
L L N + N + D N + +IP ++ L LDLSNNNL +L
Sbjct: 253 LSLVRNSLAAPPLN-LPSAHLQKLYLQD-NAISHIPYNTLAKMRELERLDLSNNNLTTLP 310
Query: 178 GVEFESLKLLRNLDLKEN 195
F+ L L L L+ N
Sbjct: 311 RGLFDDLGNLAQLLLRNN 328
>BC035281-1|AAH35281.1| 376|Homo sapiens fibromodulin protein.
Length = 376
Score = 78.6 bits (185), Expect = 2e-13
Identities = 63/232 (27%), Positives = 113/232 (48%), Gaps = 17/232 (7%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYL--EEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+N + + G+F++ L + L N + +++ + F+ + L + L +N L +P
Sbjct: 114 NNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGP 173
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKL 120
L + L + + +N++ VP+++ GL +L L L N+IQ + + L++L +L L
Sbjct: 174 LPRS---LRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDL 230
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMS--LAG 178
S N + + D + N + +P F L+++ LS+N+L + LA
Sbjct: 231 SYNHLRKVPDGL---PSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLAS 287
Query: 179 VEFESLKLLRNLDLKENALSQIPD-NTFSDCFNLEKLDLSKNKLRFINITAF 229
F S LL LDL N L +IP NT NLE L L N++ +I++F
Sbjct: 288 NTFNSSSLL-ELDLSYNQLQKIPPVNT-----NLENLYLQGNRINEFSISSF 333
Score = 50.0 bits (114), Expect = 9e-05
Identities = 46/191 (24%), Positives = 84/191 (43%), Gaps = 9/191 (4%)
Query: 103 QNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN--IPTQLFNNL 160
+N++ F ++ + +N+I +I + F+N N++ + + ++F+ L
Sbjct: 95 RNLKYLPFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKL 154
Query: 161 KCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
+ L L L +NNL + G SL R L L N +S++P+N NL L L N+
Sbjct: 155 RHLERLYLDHNNLTRMPGPLPRSL---RELHLDHNQISRVPNNALEGLENLTALYLQHNE 211
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
++ + ++ G +V S L+ L Y++ N ++P
Sbjct: 212 IQEVG-SSMRGLRSLILLDLSYNHLRKVPDGLPSALEQL---YMEHNNVYTVPDSYFRGA 267
Query: 281 PKLTIVKLSGN 291
PKL V+LS N
Sbjct: 268 PKLLYVRLSHN 278
>AL359837-1|CAH73821.1| 376|Homo sapiens fibromodulin protein.
Length = 376
Score = 78.6 bits (185), Expect = 2e-13
Identities = 63/232 (27%), Positives = 113/232 (48%), Gaps = 17/232 (7%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYL--EEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+N + + G+F++ L + L N + +++ + F+ + L + L +N L +P
Sbjct: 114 NNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGP 173
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKL 120
L + L + + +N++ VP+++ GL +L L L N+IQ + + L++L +L L
Sbjct: 174 LPRS---LRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDL 230
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMS--LAG 178
S N + + D + N + +P F L+++ LS+N+L + LA
Sbjct: 231 SYNHLRKVPDGL---PSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLAS 287
Query: 179 VEFESLKLLRNLDLKENALSQIPD-NTFSDCFNLEKLDLSKNKLRFINITAF 229
F S LL LDL N L +IP NT NLE L L N++ +I++F
Sbjct: 288 NTFNSSSLL-ELDLSYNQLQKIPPVNT-----NLENLYLQGNRINEFSISSF 333
Score = 50.0 bits (114), Expect = 9e-05
Identities = 46/191 (24%), Positives = 84/191 (43%), Gaps = 9/191 (4%)
Query: 103 QNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN--IPTQLFNNL 160
+N++ F ++ + +N+I +I + F+N N++ + + ++F+ L
Sbjct: 95 RNLKYLPFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKL 154
Query: 161 KCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
+ L L L +NNL + G SL R L L N +S++P+N NL L L N+
Sbjct: 155 RHLERLYLDHNNLTRMPGPLPRSL---RELHLDHNQISRVPNNALEGLENLTALYLQHNE 211
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
++ + ++ G +V S L+ L Y++ N ++P
Sbjct: 212 IQEVG-SSMRGLRSLILLDLSYNHLRKVPDGLPSALEQL---YMEHNNVYTVPDSYFRGA 267
Query: 281 PKLTIVKLSGN 291
PKL V+LS N
Sbjct: 268 PKLLYVRLSHN 278
>AL391728-2|CAH73692.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 78.2 bits (184), Expect = 3e-13
Identities = 68/222 (30%), Positives = 101/222 (45%), Gaps = 8/222 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
D +E+LP F LV L+ L L+ N+L+ + ++ +L +DL NN LPE L
Sbjct: 152 DAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGELPEVLD 209
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
E + + NN + +P S L L LD+SKN+I+ + + L+ L LS
Sbjct: 210 QIQNLRE-LWMDNNALQVLPG-SIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSS 267
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + + D + D N+L +P + NL L D S N L SL
Sbjct: 268 NMLQQLPD-SIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSCNELESLPST-IG 324
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L LR L + EN L ++P C N+ + L NKL F+
Sbjct: 325 YLHSLRTLAVDENFLPELP-REIGSCKNVTVMSLRSNKLEFL 365
Score = 74.1 bits (174), Expect = 5e-12
Identities = 73/269 (27%), Positives = 120/269 (44%), Gaps = 9/269 (3%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
++ +P +F L+ L L N +EE+ + F + + L + + +N L LP + A+
Sbjct: 39 LQQVPKEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTTI-ASL 96
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKI 125
L+ +DIS N V P ++ L I++ S N I + +G L NL L L+D +
Sbjct: 97 VNLKELDISKNGVQEFP-ENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFL 155
Query: 126 NNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
+ N F N LK +P + + L L LDL NN L V + ++
Sbjct: 156 EFLPAN-FGRLVKLRILELRENHLKTLPKSM-HKLAQLERLDLGNNEFGELPEV-LDQIQ 212
Query: 186 LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXX 245
LR L + NAL +P + L LD+SKN++ +++ G
Sbjct: 213 NLRELWMDNNALQVLP-GSIGKLKMLVYLDMSKNRIETVDMD-ISGCEALEDLLLSSNML 270
Query: 246 YEVHFKAFSMLKNLTTLYLDGNMFPSLPS 274
++ + +LK LTTL +D N LP+
Sbjct: 271 QQLP-DSIGLLKKLTTLKVDDNQLTMLPN 298
Score = 46.0 bits (104), Expect = 0.001
Identities = 49/224 (21%), Positives = 93/224 (41%), Gaps = 7/224 (3%)
Query: 68 LETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINN 127
+ +D S+ + VP + F +L+ L L N+I+ + F+ + L+ L + DN ++N
Sbjct: 29 ISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSN 88
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + +N ++ P + KCL ++ S N + L F L L
Sbjct: 89 L-PTTIASLVNLKELDISKNGVQEFPENI-KCCKCLTIIEASVNPISKLPD-GFTQLLNL 145
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
L L + L +P N F L L+L +N L+ + + + E
Sbjct: 146 TQLYLNDAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGE 203
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + ++NL L++D N LP ++ + L + +S N
Sbjct: 204 LP-EVLDQIQNLRELWMDNNALQVLPG-SIGKLKMLVYLDMSKN 245
Score = 39.1 bits (87), Expect = 0.17
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 4/125 (3%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I L L TL++ N L + + + L D S N L +LP +
Sbjct: 268 NMLQQLPDSI-GLLKKLTTLKVDDNQLTMLPN-TIGNLSLLEEFDCSCNELESLPSTIGY 325
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
++ L T+ + N + +P + ++ ++ L NK++ + ++ L++L LSDN
Sbjct: 326 LHS-LRTLAVDENFLPELPRE-IGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDN 383
Query: 124 KINNI 128
++ N+
Sbjct: 384 RLKNL 388
>AL391728-1|CAH73691.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 78.2 bits (184), Expect = 3e-13
Identities = 68/222 (30%), Positives = 101/222 (45%), Gaps = 8/222 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
D +E+LP F LV L+ L L+ N+L+ + ++ +L +DL NN LPE L
Sbjct: 147 DAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGELPEVLD 204
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
E + + NN + +P S L L LD+SKN+I+ + + L+ L LS
Sbjct: 205 QIQNLRE-LWMDNNALQVLPG-SIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSS 262
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + + D + D N+L +P + NL L D S N L SL
Sbjct: 263 NMLQQLPD-SIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSCNELESLPST-IG 319
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L LR L + EN L ++P C N+ + L NKL F+
Sbjct: 320 YLHSLRTLAVDENFLPELP-REIGSCKNVTVMSLRSNKLEFL 360
Score = 74.1 bits (174), Expect = 5e-12
Identities = 73/269 (27%), Positives = 120/269 (44%), Gaps = 9/269 (3%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
++ +P +F L+ L L N +EE+ + F + + L + + +N L LP + A+
Sbjct: 34 LQQVPKEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTTI-ASL 91
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKI 125
L+ +DIS N V P ++ L I++ S N I + +G L NL L L+D +
Sbjct: 92 VNLKELDISKNGVQEFP-ENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFL 150
Query: 126 NNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
+ N F N LK +P + + L L LDL NN L V + ++
Sbjct: 151 EFLPAN-FGRLVKLRILELRENHLKTLPKSM-HKLAQLERLDLGNNEFGELPEV-LDQIQ 207
Query: 186 LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXX 245
LR L + NAL +P + L LD+SKN++ +++ G
Sbjct: 208 NLRELWMDNNALQVLP-GSIGKLKMLVYLDMSKNRIETVDMD-ISGCEALEDLLLSSNML 265
Query: 246 YEVHFKAFSMLKNLTTLYLDGNMFPSLPS 274
++ + +LK LTTL +D N LP+
Sbjct: 266 QQLP-DSIGLLKKLTTLKVDDNQLTMLPN 293
Score = 46.0 bits (104), Expect = 0.001
Identities = 49/224 (21%), Positives = 93/224 (41%), Gaps = 7/224 (3%)
Query: 68 LETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINN 127
+ +D S+ + VP + F +L+ L L N+I+ + F+ + L+ L + DN ++N
Sbjct: 24 ISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSN 83
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + +N ++ P + KCL ++ S N + L F L L
Sbjct: 84 L-PTTIASLVNLKELDISKNGVQEFPENI-KCCKCLTIIEASVNPISKLPD-GFTQLLNL 140
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
L L + L +P N F L L+L +N L+ + + + E
Sbjct: 141 TQLYLNDAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGE 198
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + ++NL L++D N LP ++ + L + +S N
Sbjct: 199 LP-EVLDQIQNLRELWMDNNALQVLPG-SIGKLKMLVYLDMSKN 240
Score = 39.1 bits (87), Expect = 0.17
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 4/125 (3%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I L L TL++ N L + + + L D S N L +LP +
Sbjct: 263 NMLQQLPDSI-GLLKKLTTLKVDDNQLTMLPN-TIGNLSLLEEFDCSCNELESLPSTIGY 320
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
++ L T+ + N + +P + ++ ++ L NK++ + ++ L++L LSDN
Sbjct: 321 LHS-LRTLAVDENFLPELPRE-IGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDN 378
Query: 124 KINNI 128
++ N+
Sbjct: 379 RLKNL 383
>AL359412-2|CAH74019.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 78.2 bits (184), Expect = 3e-13
Identities = 68/222 (30%), Positives = 101/222 (45%), Gaps = 8/222 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
D +E+LP F LV L+ L L+ N+L+ + ++ +L +DL NN LPE L
Sbjct: 152 DAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGELPEVLD 209
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
E + + NN + +P S L L LD+SKN+I+ + + L+ L LS
Sbjct: 210 QIQNLRE-LWMDNNALQVLPG-SIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSS 267
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + + D + D N+L +P + NL L D S N L SL
Sbjct: 268 NMLQQLPD-SIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSCNELESLPST-IG 324
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L LR L + EN L ++P C N+ + L NKL F+
Sbjct: 325 YLHSLRTLAVDENFLPELP-REIGSCKNVTVMSLRSNKLEFL 365
Score = 74.1 bits (174), Expect = 5e-12
Identities = 73/269 (27%), Positives = 120/269 (44%), Gaps = 9/269 (3%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
++ +P +F L+ L L N +EE+ + F + + L + + +N L LP + A+
Sbjct: 39 LQQVPKEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTTI-ASL 96
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKI 125
L+ +DIS N V P ++ L I++ S N I + +G L NL L L+D +
Sbjct: 97 VNLKELDISKNGVQEFP-ENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFL 155
Query: 126 NNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
+ N F N LK +P + + L L LDL NN L V + ++
Sbjct: 156 EFLPAN-FGRLVKLRILELRENHLKTLPKSM-HKLAQLERLDLGNNEFGELPEV-LDQIQ 212
Query: 186 LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXX 245
LR L + NAL +P + L LD+SKN++ +++ G
Sbjct: 213 NLRELWMDNNALQVLP-GSIGKLKMLVYLDMSKNRIETVDMD-ISGCEALEDLLLSSNML 270
Query: 246 YEVHFKAFSMLKNLTTLYLDGNMFPSLPS 274
++ + +LK LTTL +D N LP+
Sbjct: 271 QQLP-DSIGLLKKLTTLKVDDNQLTMLPN 298
Score = 46.0 bits (104), Expect = 0.001
Identities = 49/224 (21%), Positives = 93/224 (41%), Gaps = 7/224 (3%)
Query: 68 LETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINN 127
+ +D S+ + VP + F +L+ L L N+I+ + F+ + L+ L + DN ++N
Sbjct: 29 ISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSN 88
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + +N ++ P + KCL ++ S N + L F L L
Sbjct: 89 L-PTTIASLVNLKELDISKNGVQEFPENI-KCCKCLTIIEASVNPISKLPD-GFTQLLNL 145
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
L L + L +P N F L L+L +N L+ + + + E
Sbjct: 146 TQLYLNDAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGE 203
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + ++NL L++D N LP ++ + L + +S N
Sbjct: 204 LP-EVLDQIQNLRELWMDNNALQVLPG-SIGKLKMLVYLDMSKN 245
Score = 39.1 bits (87), Expect = 0.17
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 4/125 (3%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I L L TL++ N L + + + L D S N L +LP +
Sbjct: 268 NMLQQLPDSI-GLLKKLTTLKVDDNQLTMLPN-TIGNLSLLEEFDCSCNELESLPSTIGY 325
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
++ L T+ + N + +P + ++ ++ L NK++ + ++ L++L LSDN
Sbjct: 326 LHS-LRTLAVDENFLPELPRE-IGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDN 383
Query: 124 KINNI 128
++ N+
Sbjct: 384 RLKNL 388
>AL359412-1|CAH74018.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 78.2 bits (184), Expect = 3e-13
Identities = 68/222 (30%), Positives = 101/222 (45%), Gaps = 8/222 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
D +E+LP F LV L+ L L+ N+L+ + ++ +L +DL NN LPE L
Sbjct: 147 DAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGELPEVLD 204
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
E + + NN + +P S L L LD+SKN+I+ + + L+ L LS
Sbjct: 205 QIQNLRE-LWMDNNALQVLPG-SIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSS 262
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + + D + D N+L +P + NL L D S N L SL
Sbjct: 263 NMLQQLPD-SIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSCNELESLPST-IG 319
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L LR L + EN L ++P C N+ + L NKL F+
Sbjct: 320 YLHSLRTLAVDENFLPELP-REIGSCKNVTVMSLRSNKLEFL 360
Score = 74.1 bits (174), Expect = 5e-12
Identities = 73/269 (27%), Positives = 120/269 (44%), Gaps = 9/269 (3%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
++ +P +F L+ L L N +EE+ + F + + L + + +N L LP + A+
Sbjct: 34 LQQVPKEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTTI-ASL 91
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKI 125
L+ +DIS N V P ++ L I++ S N I + +G L NL L L+D +
Sbjct: 92 VNLKELDISKNGVQEFP-ENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFL 150
Query: 126 NNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
+ N F N LK +P + + L L LDL NN L V + ++
Sbjct: 151 EFLPAN-FGRLVKLRILELRENHLKTLPKSM-HKLAQLERLDLGNNEFGELPEV-LDQIQ 207
Query: 186 LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXX 245
LR L + NAL +P + L LD+SKN++ +++ G
Sbjct: 208 NLRELWMDNNALQVLP-GSIGKLKMLVYLDMSKNRIETVDMD-ISGCEALEDLLLSSNML 265
Query: 246 YEVHFKAFSMLKNLTTLYLDGNMFPSLPS 274
++ + +LK LTTL +D N LP+
Sbjct: 266 QQLP-DSIGLLKKLTTLKVDDNQLTMLPN 293
Score = 46.0 bits (104), Expect = 0.001
Identities = 49/224 (21%), Positives = 93/224 (41%), Gaps = 7/224 (3%)
Query: 68 LETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINN 127
+ +D S+ + VP + F +L+ L L N+I+ + F+ + L+ L + DN ++N
Sbjct: 24 ISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSN 83
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + +N ++ P + KCL ++ S N + L F L L
Sbjct: 84 L-PTTIASLVNLKELDISKNGVQEFPENI-KCCKCLTIIEASVNPISKLPD-GFTQLLNL 140
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
L L + L +P N F L L+L +N L+ + + + E
Sbjct: 141 TQLYLNDAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGE 198
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + ++NL L++D N LP ++ + L + +S N
Sbjct: 199 LP-EVLDQIQNLRELWMDNNALQVLPG-SIGKLKMLVYLDMSKN 240
Score = 39.1 bits (87), Expect = 0.17
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 4/125 (3%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I L L TL++ N L + + + L D S N L +LP +
Sbjct: 263 NMLQQLPDSI-GLLKKLTTLKVDDNQLTMLPN-TIGNLSLLEEFDCSCNELESLPSTIGY 320
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
++ L T+ + N + +P + ++ ++ L NK++ + ++ L++L LSDN
Sbjct: 321 LHS-LRTLAVDENFLPELPRE-IGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDN 378
Query: 124 KINNI 128
++ N+
Sbjct: 379 RLKNL 383
>AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 232
Score = 78.2 bits (184), Expect = 3e-13
Identities = 68/222 (30%), Positives = 102/222 (45%), Gaps = 9/222 (4%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N++ L G+F L L+ LRL N+L I +AF+ L + L NN L +P +
Sbjct: 2 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 61
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ-NGTFSLKNLQILKLSD 122
L+++ + N + VP SF GL SL+ L L N + I +L LQ + L+
Sbjct: 62 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 121
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N+I++I D AF+N + NKL+ P + L L +LS N M + EF
Sbjct: 122 NRISHIPDYAFQNLTSLVVLDLNYNKLQEFPVAI-RTLGRL--QELSLNGAMDIQ--EFP 176
Query: 183 SLK---LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
LK L L L + +P L L+LS N++
Sbjct: 177 DLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQI 218
Score = 68.9 bits (161), Expect = 2e-10
Identities = 58/214 (27%), Positives = 98/214 (45%), Gaps = 11/214 (5%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
NH+ ++PG F L +LK L LQ N L I +EA L + L N + +PE+ F
Sbjct: 26 NHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFE 85
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ L + + +N + +P + L +LQ + L+ N+I +I + F +L +L +L L+
Sbjct: 86 GLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLDLNY 145
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLK---CLIFLDLSNNNLMSLAGV 179
NK+ F + + + Q F +LK L L L+ + L
Sbjct: 146 NKLQE-----FPVAIRTLGRLQELSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSG 200
Query: 180 EFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
+ L LR L+L N + ++P + C LE+
Sbjct: 201 MCQQLPRLRVLELSHNQIEELP--SLHRCQKLEE 232
Score = 66.5 bits (155), Expect = 1e-09
Identities = 46/175 (26%), Positives = 81/175 (46%), Gaps = 3/175 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + +P L +L++LRL N + + +F L H+ L +N L +P +
Sbjct: 49 NNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRAL 108
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
N L+ + ++ NR+ ++P +F L SL +LDL+ NK+Q +L LQ L L+
Sbjct: 109 NNLPALQAMTLALNRISHIPDYAFQNLTSLVVLDLNYNKLQEFPVAIRTLGRLQELSLNG 168
Query: 123 -NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSL 176
I D + R ++ +P+ + L L L+LS+N + L
Sbjct: 169 AMDIQEFPD--LKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEEL 221
Score = 62.5 bits (145), Expect = 2e-08
Identities = 58/217 (26%), Positives = 88/217 (40%), Gaps = 3/217 (1%)
Query: 76 NRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFE 134
N + + F L L+ L LS N + +I FS L +L+IL L +N++ I A
Sbjct: 2 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 61
Query: 135 NXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKE 194
D N + +P + F L L L L +N L + +L L+ + L
Sbjct: 62 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 121
Query: 195 NALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFS 254
N +S IPD F + +L LDL+ NKL+ + E F
Sbjct: 122 NRISHIPDYAFQNLTSLVVLDLNYNKLQEFPVAIRTLGRLQELSLNGAMDIQE--FPDLK 179
Query: 255 MLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+L L L LPS +P+L +++LS N
Sbjct: 180 GTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHN 216
>AL158840-2|CAH70975.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 78.2 bits (184), Expect = 3e-13
Identities = 68/222 (30%), Positives = 101/222 (45%), Gaps = 8/222 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
D +E+LP F LV L+ L L+ N+L+ + ++ +L +DL NN LPE L
Sbjct: 152 DAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGELPEVLD 209
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
E + + NN + +P S L L LD+SKN+I+ + + L+ L LS
Sbjct: 210 QIQNLRE-LWMDNNALQVLPG-SIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSS 267
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + + D + D N+L +P + NL L D S N L SL
Sbjct: 268 NMLQQLPD-SIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSCNELESLPST-IG 324
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L LR L + EN L ++P C N+ + L NKL F+
Sbjct: 325 YLHSLRTLAVDENFLPELP-REIGSCKNVTVMSLRSNKLEFL 365
Score = 74.1 bits (174), Expect = 5e-12
Identities = 73/269 (27%), Positives = 120/269 (44%), Gaps = 9/269 (3%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
++ +P +F L+ L L N +EE+ + F + + L + + +N L LP + A+
Sbjct: 39 LQQVPKEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTTI-ASL 96
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKI 125
L+ +DIS N V P ++ L I++ S N I + +G L NL L L+D +
Sbjct: 97 VNLKELDISKNGVQEFP-ENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFL 155
Query: 126 NNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
+ N F N LK +P + + L L LDL NN L V + ++
Sbjct: 156 EFLPAN-FGRLVKLRILELRENHLKTLPKSM-HKLAQLERLDLGNNEFGELPEV-LDQIQ 212
Query: 186 LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXX 245
LR L + NAL +P + L LD+SKN++ +++ G
Sbjct: 213 NLRELWMDNNALQVLP-GSIGKLKMLVYLDMSKNRIETVDMD-ISGCEALEDLLLSSNML 270
Query: 246 YEVHFKAFSMLKNLTTLYLDGNMFPSLPS 274
++ + +LK LTTL +D N LP+
Sbjct: 271 QQLP-DSIGLLKKLTTLKVDDNQLTMLPN 298
Score = 46.0 bits (104), Expect = 0.001
Identities = 49/224 (21%), Positives = 93/224 (41%), Gaps = 7/224 (3%)
Query: 68 LETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINN 127
+ +D S+ + VP + F +L+ L L N+I+ + F+ + L+ L + DN ++N
Sbjct: 29 ISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSN 88
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + +N ++ P + KCL ++ S N + L F L L
Sbjct: 89 L-PTTIASLVNLKELDISKNGVQEFPENI-KCCKCLTIIEASVNPISKLPD-GFTQLLNL 145
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
L L + L +P N F L L+L +N L+ + + + E
Sbjct: 146 TQLYLNDAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGE 203
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + ++NL L++D N LP ++ + L + +S N
Sbjct: 204 LP-EVLDQIQNLRELWMDNNALQVLPG-SIGKLKMLVYLDMSKN 245
Score = 39.1 bits (87), Expect = 0.17
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 4/125 (3%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I L L TL++ N L + + + L D S N L +LP +
Sbjct: 268 NMLQQLPDSI-GLLKKLTTLKVDDNQLTMLPN-TIGNLSLLEEFDCSCNELESLPSTIGY 325
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
++ L T+ + N + +P + ++ ++ L NK++ + ++ L++L LSDN
Sbjct: 326 LHS-LRTLAVDENFLPELPRE-IGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDN 383
Query: 124 KINNI 128
++ N+
Sbjct: 384 RLKNL 388
>AL158840-1|CAH70974.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 78.2 bits (184), Expect = 3e-13
Identities = 68/222 (30%), Positives = 101/222 (45%), Gaps = 8/222 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
D +E+LP F LV L+ L L+ N+L+ + ++ +L +DL NN LPE L
Sbjct: 147 DAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGELPEVLD 204
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
E + + NN + +P S L L LD+SKN+I+ + + L+ L LS
Sbjct: 205 QIQNLRE-LWMDNNALQVLPG-SIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSS 262
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + + D + D N+L +P + NL L D S N L SL
Sbjct: 263 NMLQQLPD-SIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSCNELESLPST-IG 319
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L LR L + EN L ++P C N+ + L NKL F+
Sbjct: 320 YLHSLRTLAVDENFLPELP-REIGSCKNVTVMSLRSNKLEFL 360
Score = 74.1 bits (174), Expect = 5e-12
Identities = 73/269 (27%), Positives = 120/269 (44%), Gaps = 9/269 (3%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
++ +P +F L+ L L N +EE+ + F + + L + + +N L LP + A+
Sbjct: 34 LQQVPKEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTTI-ASL 91
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKI 125
L+ +DIS N V P ++ L I++ S N I + +G L NL L L+D +
Sbjct: 92 VNLKELDISKNGVQEFP-ENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFL 150
Query: 126 NNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
+ N F N LK +P + + L L LDL NN L V + ++
Sbjct: 151 EFLPAN-FGRLVKLRILELRENHLKTLPKSM-HKLAQLERLDLGNNEFGELPEV-LDQIQ 207
Query: 186 LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXX 245
LR L + NAL +P + L LD+SKN++ +++ G
Sbjct: 208 NLRELWMDNNALQVLP-GSIGKLKMLVYLDMSKNRIETVDMD-ISGCEALEDLLLSSNML 265
Query: 246 YEVHFKAFSMLKNLTTLYLDGNMFPSLPS 274
++ + +LK LTTL +D N LP+
Sbjct: 266 QQLP-DSIGLLKKLTTLKVDDNQLTMLPN 293
Score = 46.0 bits (104), Expect = 0.001
Identities = 49/224 (21%), Positives = 93/224 (41%), Gaps = 7/224 (3%)
Query: 68 LETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINN 127
+ +D S+ + VP + F +L+ L L N+I+ + F+ + L+ L + DN ++N
Sbjct: 24 ISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSN 83
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + +N ++ P + KCL ++ S N + L F L L
Sbjct: 84 L-PTTIASLVNLKELDISKNGVQEFPENI-KCCKCLTIIEASVNPISKLPD-GFTQLLNL 140
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
L L + L +P N F L L+L +N L+ + + + E
Sbjct: 141 TQLYLNDAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGE 198
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + ++NL L++D N LP ++ + L + +S N
Sbjct: 199 LP-EVLDQIQNLRELWMDNNALQVLPG-SIGKLKMLVYLDMSKN 240
Score = 39.1 bits (87), Expect = 0.17
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 4/125 (3%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I L L TL++ N L + + + L D S N L +LP +
Sbjct: 263 NMLQQLPDSI-GLLKKLTTLKVDDNQLTMLPN-TIGNLSLLEEFDCSCNELESLPSTIGY 320
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
++ L T+ + N + +P + ++ ++ L NK++ + ++ L++L LSDN
Sbjct: 321 LHS-LRTLAVDENFLPELPRE-IGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDN 378
Query: 124 KINNI 128
++ N+
Sbjct: 379 RLKNL 383
>AL157948-2|CAI22426.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 78.2 bits (184), Expect = 3e-13
Identities = 68/222 (30%), Positives = 101/222 (45%), Gaps = 8/222 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
D +E+LP F LV L+ L L+ N+L+ + ++ +L +DL NN LPE L
Sbjct: 152 DAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGELPEVLD 209
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
E + + NN + +P S L L LD+SKN+I+ + + L+ L LS
Sbjct: 210 QIQNLRE-LWMDNNALQVLPG-SIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSS 267
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + + D + D N+L +P + NL L D S N L SL
Sbjct: 268 NMLQQLPD-SIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSCNELESLPST-IG 324
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L LR L + EN L ++P C N+ + L NKL F+
Sbjct: 325 YLHSLRTLAVDENFLPELP-REIGSCKNVTVMSLRSNKLEFL 365
Score = 74.1 bits (174), Expect = 5e-12
Identities = 73/269 (27%), Positives = 120/269 (44%), Gaps = 9/269 (3%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
++ +P +F L+ L L N +EE+ + F + + L + + +N L LP + A+
Sbjct: 39 LQQVPKEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTTI-ASL 96
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKI 125
L+ +DIS N V P ++ L I++ S N I + +G L NL L L+D +
Sbjct: 97 VNLKELDISKNGVQEFP-ENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFL 155
Query: 126 NNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
+ N F N LK +P + + L L LDL NN L V + ++
Sbjct: 156 EFLPAN-FGRLVKLRILELRENHLKTLPKSM-HKLAQLERLDLGNNEFGELPEV-LDQIQ 212
Query: 186 LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXX 245
LR L + NAL +P + L LD+SKN++ +++ G
Sbjct: 213 NLRELWMDNNALQVLP-GSIGKLKMLVYLDMSKNRIETVDMD-ISGCEALEDLLLSSNML 270
Query: 246 YEVHFKAFSMLKNLTTLYLDGNMFPSLPS 274
++ + +LK LTTL +D N LP+
Sbjct: 271 QQLP-DSIGLLKKLTTLKVDDNQLTMLPN 298
Score = 46.0 bits (104), Expect = 0.001
Identities = 49/224 (21%), Positives = 93/224 (41%), Gaps = 7/224 (3%)
Query: 68 LETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINN 127
+ +D S+ + VP + F +L+ L L N+I+ + F+ + L+ L + DN ++N
Sbjct: 29 ISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSN 88
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + +N ++ P + KCL ++ S N + L F L L
Sbjct: 89 L-PTTIASLVNLKELDISKNGVQEFPENI-KCCKCLTIIEASVNPISKLPD-GFTQLLNL 145
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
L L + L +P N F L L+L +N L+ + + + E
Sbjct: 146 TQLYLNDAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGE 203
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + ++NL L++D N LP ++ + L + +S N
Sbjct: 204 LP-EVLDQIQNLRELWMDNNALQVLPG-SIGKLKMLVYLDMSKN 245
Score = 39.1 bits (87), Expect = 0.17
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 4/125 (3%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I L L TL++ N L + + + L D S N L +LP +
Sbjct: 268 NMLQQLPDSI-GLLKKLTTLKVDDNQLTMLPN-TIGNLSLLEEFDCSCNELESLPSTIGY 325
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
++ L T+ + N + +P + ++ ++ L NK++ + ++ L++L LSDN
Sbjct: 326 LHS-LRTLAVDENFLPELPRE-IGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDN 383
Query: 124 KINNI 128
++ N+
Sbjct: 384 RLKNL 388
>AL157948-1|CAI22425.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 78.2 bits (184), Expect = 3e-13
Identities = 68/222 (30%), Positives = 101/222 (45%), Gaps = 8/222 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
D +E+LP F LV L+ L L+ N+L+ + ++ +L +DL NN LPE L
Sbjct: 147 DAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGELPEVLD 204
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
E + + NN + +P S L L LD+SKN+I+ + + L+ L LS
Sbjct: 205 QIQNLRE-LWMDNNALQVLPG-SIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSS 262
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + + D + D N+L +P + NL L D S N L SL
Sbjct: 263 NMLQQLPD-SIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSCNELESLPST-IG 319
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L LR L + EN L ++P C N+ + L NKL F+
Sbjct: 320 YLHSLRTLAVDENFLPELP-REIGSCKNVTVMSLRSNKLEFL 360
Score = 74.1 bits (174), Expect = 5e-12
Identities = 73/269 (27%), Positives = 120/269 (44%), Gaps = 9/269 (3%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
++ +P +F L+ L L N +EE+ + F + + L + + +N L LP + A+
Sbjct: 34 LQQVPKEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTTI-ASL 91
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKI 125
L+ +DIS N V P ++ L I++ S N I + +G L NL L L+D +
Sbjct: 92 VNLKELDISKNGVQEFP-ENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFL 150
Query: 126 NNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
+ N F N LK +P + + L L LDL NN L V + ++
Sbjct: 151 EFLPAN-FGRLVKLRILELRENHLKTLPKSM-HKLAQLERLDLGNNEFGELPEV-LDQIQ 207
Query: 186 LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXX 245
LR L + NAL +P + L LD+SKN++ +++ G
Sbjct: 208 NLRELWMDNNALQVLP-GSIGKLKMLVYLDMSKNRIETVDMD-ISGCEALEDLLLSSNML 265
Query: 246 YEVHFKAFSMLKNLTTLYLDGNMFPSLPS 274
++ + +LK LTTL +D N LP+
Sbjct: 266 QQLP-DSIGLLKKLTTLKVDDNQLTMLPN 293
Score = 46.0 bits (104), Expect = 0.001
Identities = 49/224 (21%), Positives = 93/224 (41%), Gaps = 7/224 (3%)
Query: 68 LETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINN 127
+ +D S+ + VP + F +L+ L L N+I+ + F+ + L+ L + DN ++N
Sbjct: 24 ISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSN 83
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + +N ++ P + KCL ++ S N + L F L L
Sbjct: 84 L-PTTIASLVNLKELDISKNGVQEFPENI-KCCKCLTIIEASVNPISKLPD-GFTQLLNL 140
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
L L + L +P N F L L+L +N L+ + + + E
Sbjct: 141 TQLYLNDAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGE 198
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + ++NL L++D N LP ++ + L + +S N
Sbjct: 199 LP-EVLDQIQNLRELWMDNNALQVLPG-SIGKLKMLVYLDMSKN 240
Score = 39.1 bits (87), Expect = 0.17
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 4/125 (3%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I L L TL++ N L + + + L D S N L +LP +
Sbjct: 263 NMLQQLPDSI-GLLKKLTTLKVDDNQLTMLPN-TIGNLSLLEEFDCSCNELESLPSTIGY 320
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
++ L T+ + N + +P + ++ ++ L NK++ + ++ L++L LSDN
Sbjct: 321 LHS-LRTLAVDENFLPELPRE-IGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDN 378
Query: 124 KINNI 128
++ N+
Sbjct: 379 RLKNL 383
>AL117353-1|CAI23423.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 78.2 bits (184), Expect = 3e-13
Identities = 68/222 (30%), Positives = 101/222 (45%), Gaps = 8/222 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
D +E+LP F LV L+ L L+ N+L+ + ++ +L +DL NN LPE L
Sbjct: 152 DAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGELPEVLD 209
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
E + + NN + +P S L L LD+SKN+I+ + + L+ L LS
Sbjct: 210 QIQNLRE-LWMDNNALQVLPG-SIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSS 267
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + + D + D N+L +P + NL L D S N L SL
Sbjct: 268 NMLQQLPD-SIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSCNELESLPST-IG 324
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L LR L + EN L ++P C N+ + L NKL F+
Sbjct: 325 YLHSLRTLAVDENFLPELP-REIGSCKNVTVMSLRSNKLEFL 365
Score = 74.1 bits (174), Expect = 5e-12
Identities = 73/269 (27%), Positives = 120/269 (44%), Gaps = 9/269 (3%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
++ +P +F L+ L L N +EE+ + F + + L + + +N L LP + A+
Sbjct: 39 LQQVPKEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTTI-ASL 96
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKI 125
L+ +DIS N V P ++ L I++ S N I + +G L NL L L+D +
Sbjct: 97 VNLKELDISKNGVQEFP-ENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFL 155
Query: 126 NNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
+ N F N LK +P + + L L LDL NN L V + ++
Sbjct: 156 EFLPAN-FGRLVKLRILELRENHLKTLPKSM-HKLAQLERLDLGNNEFGELPEV-LDQIQ 212
Query: 186 LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXX 245
LR L + NAL +P + L LD+SKN++ +++ G
Sbjct: 213 NLRELWMDNNALQVLP-GSIGKLKMLVYLDMSKNRIETVDMD-ISGCEALEDLLLSSNML 270
Query: 246 YEVHFKAFSMLKNLTTLYLDGNMFPSLPS 274
++ + +LK LTTL +D N LP+
Sbjct: 271 QQLP-DSIGLLKKLTTLKVDDNQLTMLPN 298
Score = 46.0 bits (104), Expect = 0.001
Identities = 49/224 (21%), Positives = 93/224 (41%), Gaps = 7/224 (3%)
Query: 68 LETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINN 127
+ +D S+ + VP + F +L+ L L N+I+ + F+ + L+ L + DN ++N
Sbjct: 29 ISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSN 88
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + +N ++ P + KCL ++ S N + L F L L
Sbjct: 89 L-PTTIASLVNLKELDISKNGVQEFPENI-KCCKCLTIIEASVNPISKLPD-GFTQLLNL 145
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
L L + L +P N F L L+L +N L+ + + + E
Sbjct: 146 TQLYLNDAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGE 203
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + ++NL L++D N LP ++ + L + +S N
Sbjct: 204 LP-EVLDQIQNLRELWMDNNALQVLPG-SIGKLKMLVYLDMSKN 245
Score = 39.1 bits (87), Expect = 0.17
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 4/125 (3%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I L L TL++ N L + + + L D S N L +LP +
Sbjct: 268 NMLQQLPDSI-GLLKKLTTLKVDDNQLTMLPN-TIGNLSLLEEFDCSCNELESLPSTIGY 325
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
++ L T+ + N + +P + ++ ++ L NK++ + ++ L++L LSDN
Sbjct: 326 LHS-LRTLAVDENFLPELPRE-IGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDN 383
Query: 124 KINNI 128
++ N+
Sbjct: 384 RLKNL 388
>AF434715-1|AAL28133.1| 1537|Homo sapiens densin-180 protein.
Length = 1537
Score = 78.2 bits (184), Expect = 3e-13
Identities = 68/222 (30%), Positives = 101/222 (45%), Gaps = 8/222 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
D +E+LP F LV L+ L L+ N+L+ + ++ +L +DL NN LPE L
Sbjct: 147 DAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGELPEVLD 204
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSD 122
E + + NN + +P S L L LD+SKN+I+ + + L+ L LS
Sbjct: 205 QIQNLRE-LWMDNNALQVLPG-SIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSS 262
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFE 182
N + + D + D N+L +P + NL L D S N L SL
Sbjct: 263 NMLQQLPD-SIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSCNELESLPST-IG 319
Query: 183 SLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
L LR L + EN L ++P C N+ + L NKL F+
Sbjct: 320 YLHSLRTLAVDENFLPELP-REIGSCKNVTVMSLRSNKLEFL 360
Score = 74.1 bits (174), Expect = 5e-12
Identities = 73/269 (27%), Positives = 120/269 (44%), Gaps = 9/269 (3%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
++ +P +F L+ L L N +EE+ + F + + L + + +N L LP + A+
Sbjct: 34 LQQVPKEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTTI-ASL 91
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKI 125
L+ +DIS N V P ++ L I++ S N I + +G L NL L L+D +
Sbjct: 92 VNLKELDISKNGVQEFP-ENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFL 150
Query: 126 NNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLK 185
+ N F N LK +P + + L L LDL NN L V + ++
Sbjct: 151 EFLPAN-FGRLVKLRILELRENHLKTLPKSM-HKLAQLERLDLGNNEFGELPEV-LDQIQ 207
Query: 186 LLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXX 245
LR L + NAL +P + L LD+SKN++ +++ G
Sbjct: 208 NLRELWMDNNALQVLP-GSIGKLKMLVYLDMSKNRIETVDMD-ISGCEALEDLLLSSNML 265
Query: 246 YEVHFKAFSMLKNLTTLYLDGNMFPSLPS 274
++ + +LK LTTL +D N LP+
Sbjct: 266 QQLP-DSIGLLKKLTTLKVDDNQLTMLPN 293
Score = 46.0 bits (104), Expect = 0.001
Identities = 49/224 (21%), Positives = 93/224 (41%), Gaps = 7/224 (3%)
Query: 68 LETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINN 127
+ +D S+ + VP + F +L+ L L N+I+ + F+ + L+ L + DN ++N
Sbjct: 24 ISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSN 83
Query: 128 ISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
+ + +N ++ P + KCL ++ S N + L F L L
Sbjct: 84 L-PTTIASLVNLKELDISKNGVQEFPENI-KCCKCLTIIEASVNPISKLPD-GFTQLLNL 140
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
L L + L +P N F L L+L +N L+ + + + E
Sbjct: 141 TQLYLNDAFLEFLPAN-FGRLVKLRILELRENHLKTLP-KSMHKLAQLERLDLGNNEFGE 198
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + ++NL L++D N LP ++ + L + +S N
Sbjct: 199 LP-EVLDQIQNLRELWMDNNALQVLPG-SIGKLKMLVYLDMSKN 240
Score = 39.1 bits (87), Expect = 0.17
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 4/125 (3%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ LP I L L TL++ N L + + + L D S N L +LP +
Sbjct: 263 NMLQQLPDSI-GLLKKLTTLKVDDNQLTMLPN-TIGNLSLLEEFDCSCNELESLPSTIGY 320
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDN 123
++ L T+ + N + +P + ++ ++ L NK++ + ++ L++L LSDN
Sbjct: 321 LHS-LRTLAVDENFLPELPRE-IGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDN 378
Query: 124 KINNI 128
++ N+
Sbjct: 379 RLKNL 383
>BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein.
Length = 661
Score = 77.8 bits (183), Expect = 4e-13
Identities = 68/206 (33%), Positives = 99/206 (48%), Gaps = 13/206 (6%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYT--LPEKLFANNTFLETIDISNNRVVY 80
L LQ N LE+I E + +L ++L NN L + LPEK F + T L + ++NN++
Sbjct: 149 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTL 208
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLK-NLQILKLSDNKINN--ISDNAFENXX 137
P FL +L +D + N + I TF K NL+ + L +NK+ + + DN F
Sbjct: 209 AP--RFLP-NALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSS 265
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
N L+++P L L L L NN L + F L LR L L+ N L
Sbjct: 266 NVEVLILSSNFLRHVPKHL---PPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYL 322
Query: 198 SQ--IPDNTFSDCFNLEKLDLSKNKL 221
+ + + TF +LE LDLS N L
Sbjct: 323 TDEGLDNETFWKLSSLEYLDLSSNNL 348
Score = 69.7 bits (163), Expect = 1e-10
Identities = 59/212 (27%), Positives = 101/212 (47%), Gaps = 12/212 (5%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F+ L L T+ L N LE + S + L + +N + + + FA FLE +++
Sbjct: 403 FQGLKRLHTVHLYNNALERVPSGLPRRVRTLM---ILHNQITGIGREDFATTYFLEELNL 459
Query: 74 SNNRVV--YVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDN 131
S NR+ V D+F L L+ LDLS N++ + G +N+ +LK+ N++ ++
Sbjct: 460 SYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGL--PRNVHVLKVKRNELAALARG 517
Query: 132 AFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRN 189
A N+L++ + + + +L L LD++ N L + ESL+ L
Sbjct: 518 ALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLY- 576
Query: 190 LDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
L+ N +S +P N F NL+ + L NKL
Sbjct: 577 --LQNNKISAVPANAFDSTPNLKGIFLRFNKL 606
Score = 69.3 bits (162), Expect = 1e-10
Identities = 62/210 (29%), Positives = 101/210 (48%), Gaps = 15/210 (7%)
Query: 20 LKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYT--LPEKLFANNTFLETIDISNNR 77
L L L+ N LE+I AF+ L + L NNYL L + F + LE +D+S+N
Sbjct: 288 LYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNN 347
Query: 78 VVYVPSDSFLGL-YSLQILDLSKNKIQNIQ-NGTFSLKNLQILKLSDNKI--NNISDNAF 133
+ VP+ GL SL +L L KN I+++ N +++L+ L L N++ I AF
Sbjct: 348 LSRVPA----GLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAF 403
Query: 134 ENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLK 193
+ N L+ +P+ L ++ L+ L +N + + +F + L L+L
Sbjct: 404 QGLKRLHTVHLYNNALERVPSGLPRRVRTLMIL---HNQITGIGREDFATTYFLEELNLS 460
Query: 194 ENALS--QIPDNTFSDCFNLEKLDLSKNKL 221
N ++ Q+ + F L LDLS N+L
Sbjct: 461 YNRITSPQVHRDAFRKLRLLRSLDLSGNRL 490
Score = 68.1 bits (159), Expect = 3e-10
Identities = 64/218 (29%), Positives = 97/218 (44%), Gaps = 12/218 (5%)
Query: 9 LPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFL 68
LP FE L NL L L N L + F L VD + NYL + F L
Sbjct: 185 LPEKAFEHLTNLNYLYLANNKLTL--APRFLPNA-LISVDFAANYLTKIYGLTFGQKPNL 241
Query: 69 ETIDISNNRVVY--VPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKIN 126
++ + NN++ +P + F G ++++L LS N ++++ L L L +NK+
Sbjct: 242 RSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPA--LYKLHLKNNKLE 299
Query: 127 NISDNAFENXXXXXXXXXDRNKL--KNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESL 184
I AF N L + + + F L L +LDLS+NNL + SL
Sbjct: 300 KIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSL 359
Query: 185 KLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
LL L++NA+ + N + +LE L L N+LR
Sbjct: 360 VLLH---LEKNAIRSVDANVLTPIRSLEYLLLHSNQLR 394
Score = 66.9 bits (156), Expect = 7e-10
Identities = 61/206 (29%), Positives = 95/206 (46%), Gaps = 13/206 (6%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYL--EEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+N +E +P G F L +L+ L LQ NYL E +D+E F L ++DLS+N L +P
Sbjct: 295 NNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAG 354
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI--QNIQNGTF-SLKNLQI 117
L + L + + N + V ++ + SL+ L L N++ Q I F LK L
Sbjct: 355 LPRS---LVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHT 411
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMS-- 175
+ L +N + + N++ I + F L L+LS N + S
Sbjct: 412 VHLYNNALERVPSGLPRRVRTLMIL---HNQITGIGREDFATTYFLEELNLSYNRITSPQ 468
Query: 176 LAGVEFESLKLLRNLDLKENALSQIP 201
+ F L+LLR+LDL N L +P
Sbjct: 469 VHRDAFRKLRLLRSLDLSGNRLHTLP 494
Score = 55.6 bits (128), Expect = 2e-06
Identities = 58/204 (28%), Positives = 87/204 (42%), Gaps = 13/204 (6%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINN--ISDNAFENXXXXXXXXXDRNKLKN 151
L L N+++ I S L L+ L L +N++ + + + AFE+ NKL
Sbjct: 149 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTL 208
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ--IPDNTFSDCF 209
P L N LI +D + N L + G+ F LR++ L N L+ +PDN F+
Sbjct: 209 APRFLPN---ALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSS 265
Query: 210 NLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
N+E L LS N LR + + ++ AFS L +L LYL N
Sbjct: 266 NVEVLILSSNFLRHV---PKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYL 322
Query: 270 --PSLPSRTLDYMPKLTIVKLSGN 291
L + T + L + LS N
Sbjct: 323 TDEGLDNETFWKLSSLEYLDLSSN 346
Score = 54.4 bits (125), Expect = 4e-06
Identities = 48/189 (25%), Positives = 88/189 (46%), Gaps = 13/189 (6%)
Query: 14 FESLVNLKTLRLQRNYLE--EIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETI 71
F + L+ L L N + ++ +AF + L +DLS N L+TLP L N + +
Sbjct: 448 FATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRN---VHVL 504
Query: 72 DISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT---FSLKNLQILKLSDNKINNI 128
+ N + + + G+ L+ L L+ N++++ G L +LQ+L ++ N++ I
Sbjct: 505 KVKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEI 564
Query: 129 SDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCL--IFLDLSNNNLMSLAGVEFESLKL 186
+ E+ NK+ +P F++ L IFL + + S+ F LK
Sbjct: 565 PEGLPES---LEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKH 621
Query: 187 LRNLDLKEN 195
L+ LD++ N
Sbjct: 622 LQVLDIEGN 630
>AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein.
Length = 642
Score = 77.8 bits (183), Expect = 4e-13
Identities = 68/206 (33%), Positives = 99/206 (48%), Gaps = 13/206 (6%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYT--LPEKLFANNTFLETIDISNNRVVY 80
L LQ N LE+I E + +L ++L NN L + LPEK F + T L + ++NN++
Sbjct: 130 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTL 189
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLK-NLQILKLSDNKINN--ISDNAFENXX 137
P FL +L +D + N + I TF K NL+ + L +NK+ + + DN F
Sbjct: 190 AP--RFLP-NALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSS 246
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
N L+++P L L L L NN L + F L LR L L+ N L
Sbjct: 247 NVEVLILSSNFLRHVPKHL---PPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYL 303
Query: 198 SQ--IPDNTFSDCFNLEKLDLSKNKL 221
+ + + TF +LE LDLS N L
Sbjct: 304 TDEGLDNETFWKLSSLEYLDLSSNNL 329
Score = 69.7 bits (163), Expect = 1e-10
Identities = 59/212 (27%), Positives = 101/212 (47%), Gaps = 12/212 (5%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F+ L L T+ L N LE + S + L + +N + + + FA FLE +++
Sbjct: 384 FQGLKRLHTVHLYNNALERVPSGLPRRVRTLM---ILHNQITGIGREDFATTYFLEELNL 440
Query: 74 SNNRVV--YVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDN 131
S NR+ V D+F L L+ LDLS N++ + G +N+ +LK+ N++ ++
Sbjct: 441 SYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGL--PRNVHVLKVKRNELAALARG 498
Query: 132 AFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRN 189
A N+L++ + + + +L L LD++ N L + ESL+ L
Sbjct: 499 ALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLY- 557
Query: 190 LDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
L+ N +S +P N F NL+ + L NKL
Sbjct: 558 --LQNNKISAVPANAFDSTPNLKGIFLRFNKL 587
Score = 69.3 bits (162), Expect = 1e-10
Identities = 62/210 (29%), Positives = 101/210 (48%), Gaps = 15/210 (7%)
Query: 20 LKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYT--LPEKLFANNTFLETIDISNNR 77
L L L+ N LE+I AF+ L + L NNYL L + F + LE +D+S+N
Sbjct: 269 LYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNN 328
Query: 78 VVYVPSDSFLGL-YSLQILDLSKNKIQNIQ-NGTFSLKNLQILKLSDNKI--NNISDNAF 133
+ VP+ GL SL +L L KN I+++ N +++L+ L L N++ I AF
Sbjct: 329 LSRVPA----GLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAF 384
Query: 134 ENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLK 193
+ N L+ +P+ L ++ L+ L +N + + +F + L L+L
Sbjct: 385 QGLKRLHTVHLYNNALERVPSGLPRRVRTLMIL---HNQITGIGREDFATTYFLEELNLS 441
Query: 194 ENALS--QIPDNTFSDCFNLEKLDLSKNKL 221
N ++ Q+ + F L LDLS N+L
Sbjct: 442 YNRITSPQVHRDAFRKLRLLRSLDLSGNRL 471
Score = 68.1 bits (159), Expect = 3e-10
Identities = 64/218 (29%), Positives = 97/218 (44%), Gaps = 12/218 (5%)
Query: 9 LPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFL 68
LP FE L NL L L N L + F L VD + NYL + F L
Sbjct: 166 LPEKAFEHLTNLNYLYLANNKLTL--APRFLPNA-LISVDFAANYLTKIYGLTFGQKPNL 222
Query: 69 ETIDISNNRVVY--VPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKIN 126
++ + NN++ +P + F G ++++L LS N ++++ L L L +NK+
Sbjct: 223 RSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPA--LYKLHLKNNKLE 280
Query: 127 NISDNAFENXXXXXXXXXDRNKL--KNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESL 184
I AF N L + + + F L L +LDLS+NNL + SL
Sbjct: 281 KIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSL 340
Query: 185 KLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
LL L++NA+ + N + +LE L L N+LR
Sbjct: 341 VLLH---LEKNAIRSVDANVLTPIRSLEYLLLHSNQLR 375
Score = 66.9 bits (156), Expect = 7e-10
Identities = 61/206 (29%), Positives = 95/206 (46%), Gaps = 13/206 (6%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYL--EEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+N +E +P G F L +L+ L LQ NYL E +D+E F L ++DLS+N L +P
Sbjct: 276 NNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAG 335
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI--QNIQNGTF-SLKNLQI 117
L + L + + N + V ++ + SL+ L L N++ Q I F LK L
Sbjct: 336 LPRS---LVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHT 392
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMS-- 175
+ L +N + + N++ I + F L L+LS N + S
Sbjct: 393 VHLYNNALERVPSGLPRRVRTLMIL---HNQITGIGREDFATTYFLEELNLSYNRITSPQ 449
Query: 176 LAGVEFESLKLLRNLDLKENALSQIP 201
+ F L+LLR+LDL N L +P
Sbjct: 450 VHRDAFRKLRLLRSLDLSGNRLHTLP 475
Score = 55.6 bits (128), Expect = 2e-06
Identities = 58/204 (28%), Positives = 87/204 (42%), Gaps = 13/204 (6%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINN--ISDNAFENXXXXXXXXXDRNKLKN 151
L L N+++ I S L L+ L L +N++ + + + AFE+ NKL
Sbjct: 130 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTL 189
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ--IPDNTFSDCF 209
P L N LI +D + N L + G+ F LR++ L N L+ +PDN F+
Sbjct: 190 APRFLPN---ALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSS 246
Query: 210 NLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
N+E L LS N LR + + ++ AFS L +L LYL N
Sbjct: 247 NVEVLILSSNFLRHV---PKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYL 303
Query: 270 --PSLPSRTLDYMPKLTIVKLSGN 291
L + T + L + LS N
Sbjct: 304 TDEGLDNETFWKLSSLEYLDLSSN 327
Score = 54.4 bits (125), Expect = 4e-06
Identities = 48/189 (25%), Positives = 88/189 (46%), Gaps = 13/189 (6%)
Query: 14 FESLVNLKTLRLQRNYLE--EIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETI 71
F + L+ L L N + ++ +AF + L +DLS N L+TLP L N + +
Sbjct: 429 FATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRN---VHVL 485
Query: 72 DISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGT---FSLKNLQILKLSDNKINNI 128
+ N + + + G+ L+ L L+ N++++ G L +LQ+L ++ N++ I
Sbjct: 486 KVKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEI 545
Query: 129 SDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCL--IFLDLSNNNLMSLAGVEFESLKL 186
+ E+ NK+ +P F++ L IFL + + S+ F LK
Sbjct: 546 PEGLPES---LEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKH 602
Query: 187 LRNLDLKEN 195
L+ LD++ N
Sbjct: 603 LQVLDIEGN 611
>AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein.
Length = 613
Score = 77.8 bits (183), Expect = 4e-13
Identities = 68/206 (33%), Positives = 99/206 (48%), Gaps = 13/206 (6%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYT--LPEKLFANNTFLETIDISNNRVVY 80
L LQ N LE+I E + +L ++L NN L + LPEK F + T L + ++NN++
Sbjct: 101 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTL 160
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLK-NLQILKLSDNKINN--ISDNAFENXX 137
P FL +L +D + N + I TF K NL+ + L +NK+ + + DN F
Sbjct: 161 AP--RFLP-NALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSS 217
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
N L+++P L L L L NN L + F L LR L L+ N L
Sbjct: 218 NVEVLILSSNFLRHVPKHL---PPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYL 274
Query: 198 SQ--IPDNTFSDCFNLEKLDLSKNKL 221
+ + + TF +LE LDLS N L
Sbjct: 275 TDEGLDNETFWKLSSLEYLDLSSNNL 300
Score = 70.1 bits (164), Expect = 8e-11
Identities = 62/213 (29%), Positives = 102/213 (47%), Gaps = 15/213 (7%)
Query: 20 LKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYT--LPEKLFANNTFLETIDISNNR 77
L L L+ N LE+I AF+ L + L NNYL L + F + LE +D+S+N
Sbjct: 240 LYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNN 299
Query: 78 VVYVPSDSFLGL-YSLQILDLSKNKIQNIQ-NGTFSLKNLQILKLSDNKI--NNISDNAF 133
+ VP+ GL SL +L L KN I+++ N +++L+ L L N++ I AF
Sbjct: 300 LSRVPA----GLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAF 355
Query: 134 ENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLK 193
+ N L+ +P+ L ++ L+ L +N + + +F + L L+L
Sbjct: 356 QGLKRLHTVHLYNNALERVPSGLPRRVRTLMIL---HNQITGIGREDFATTYFLEELNLS 412
Query: 194 ENALS--QIPDNTFSDCFNLEKLDLSKNKLRFI 224
N ++ Q+ + F L LDLS N+L +
Sbjct: 413 YNRITSPQVHRDAFRKLRLLRSLDLSGNRLHML 445
Score = 68.9 bits (161), Expect = 2e-10
Identities = 59/212 (27%), Positives = 101/212 (47%), Gaps = 12/212 (5%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F+ L L T+ L N LE + S + L + +N + + + FA FLE +++
Sbjct: 355 FQGLKRLHTVHLYNNALERVPSGLPRRVRTLM---ILHNQITGIGREDFATTYFLEELNL 411
Query: 74 SNNRVV--YVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDN 131
S NR+ V D+F L L+ LDLS N++ + G +N+ +LK+ N++ ++
Sbjct: 412 SYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHMLPPGL--PRNVHVLKVKRNELAALARG 469
Query: 132 AFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRN 189
A N+L++ + + + +L L LD++ N L + ESL+ L
Sbjct: 470 ALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLY- 528
Query: 190 LDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
L+ N +S +P N F NL+ + L NKL
Sbjct: 529 --LQNNKISAVPANAFDSTPNLKGIFLRFNKL 558
Score = 67.3 bits (157), Expect = 6e-10
Identities = 61/206 (29%), Positives = 95/206 (46%), Gaps = 13/206 (6%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYL--EEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+N +E +P G F L +L+ L LQ NYL E +D+E F L ++DLS+N L +P
Sbjct: 247 NNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAG 306
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI--QNIQNGTF-SLKNLQI 117
L + L + + N + V ++ + SL+ L L N++ Q I F LK L
Sbjct: 307 LPRS---LVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHT 363
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMS-- 175
+ L +N + + N++ I + F L L+LS N + S
Sbjct: 364 VHLYNNALERVPSGLPRRVRTLMIL---HNQITGIGREDFATTYFLEELNLSYNRITSPQ 420
Query: 176 LAGVEFESLKLLRNLDLKENALSQIP 201
+ F L+LLR+LDL N L +P
Sbjct: 421 VHRDAFRKLRLLRSLDLSGNRLHMLP 446
Score = 55.6 bits (128), Expect = 2e-06
Identities = 58/204 (28%), Positives = 87/204 (42%), Gaps = 13/204 (6%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINN--ISDNAFENXXXXXXXXXDRNKLKN 151
L L N+++ I S L L+ L L +N++ + + + AFE+ NKL
Sbjct: 101 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTL 160
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ--IPDNTFSDCF 209
P L N LI +D + N L + G+ F LR++ L N L+ +PDN F+
Sbjct: 161 APRFLPN---ALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSS 217
Query: 210 NLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
N+E L LS N LR + + ++ AFS L +L LYL N
Sbjct: 218 NVEVLILSSNFLRHV---PKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYL 274
Query: 270 --PSLPSRTLDYMPKLTIVKLSGN 291
L + T + L + LS N
Sbjct: 275 TDEGLDNETFWKLSSLEYLDLSSN 298
>AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein.
Length = 642
Score = 77.8 bits (183), Expect = 4e-13
Identities = 68/206 (33%), Positives = 99/206 (48%), Gaps = 13/206 (6%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYT--LPEKLFANNTFLETIDISNNRVVY 80
L LQ N LE+I E + +L ++L NN L + LPEK F + T L + ++NN++
Sbjct: 130 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTL 189
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLK-NLQILKLSDNKINN--ISDNAFENXX 137
P FL +L +D + N + I TF K NL+ + L +NK+ + + DN F
Sbjct: 190 AP--RFLP-NALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSS 246
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
N L+++P L L L L NN L + F L LR L L+ N L
Sbjct: 247 NVEVLILSSNFLRHVPKHL---PPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYL 303
Query: 198 SQ--IPDNTFSDCFNLEKLDLSKNKL 221
+ + + TF +LE LDLS N L
Sbjct: 304 TDEGLDNETFWKLSSLEYLDLSSNNL 329
Score = 69.3 bits (162), Expect = 1e-10
Identities = 62/210 (29%), Positives = 101/210 (48%), Gaps = 15/210 (7%)
Query: 20 LKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYT--LPEKLFANNTFLETIDISNNR 77
L L L+ N LE+I AF+ L + L NNYL L + F + LE +D+S+N
Sbjct: 269 LYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNN 328
Query: 78 VVYVPSDSFLGL-YSLQILDLSKNKIQNIQ-NGTFSLKNLQILKLSDNKI--NNISDNAF 133
+ VP+ GL SL +L L KN I+++ N +++L+ L L N++ I AF
Sbjct: 329 LSRVPA----GLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAF 384
Query: 134 ENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLK 193
+ N L+ +P+ L ++ L+ L +N + + +F + L L+L
Sbjct: 385 QGLKRLHTVHLYNNALERVPSGLPRRVRTLMIL---HNQITGIGREDFATTYFLEELNLS 441
Query: 194 ENALS--QIPDNTFSDCFNLEKLDLSKNKL 221
N ++ Q+ + F L LDLS N+L
Sbjct: 442 YNRITSPQVHRDAFRKLRLLRSLDLSGNRL 471
Score = 69.3 bits (162), Expect = 1e-10
Identities = 59/212 (27%), Positives = 101/212 (47%), Gaps = 12/212 (5%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F+ L L T+ L N LE + S + L + +N + + + FA FLE +++
Sbjct: 384 FQGLKRLHTVHLYNNALERVPSGLPRRVRTLM---ILHNQITGIGREDFATTYFLEELNL 440
Query: 74 SNNRVV--YVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDN 131
S NR+ V D+F L L+ LDLS N++ + G +N+ +LK+ N++ ++
Sbjct: 441 SYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGL--PRNVHVLKVKRNELAALARG 498
Query: 132 AFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRN 189
A N+L++ + + + +L L LD++ N L + ESL+ L
Sbjct: 499 ALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLY- 557
Query: 190 LDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
L+ N +S +P N F NL+ + L NKL
Sbjct: 558 --LQNNKISAVPANAFDSTPNLKGIFLRFNKL 587
Score = 67.3 bits (157), Expect = 6e-10
Identities = 67/236 (28%), Positives = 106/236 (44%), Gaps = 16/236 (6%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYL--EEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+N +E +P G F L +L+ L LQ NYL E +D+E F L ++DLS+N L +P
Sbjct: 276 NNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAG 335
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI--QNIQNGTF-SLKNLQI 117
L + L + + N + V ++ + SL+ L L N++ Q I F LK L
Sbjct: 336 LPRS---LVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHT 392
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMS-- 175
+ L +N + + N++ I + F L L+LS N + S
Sbjct: 393 VHLYNNALERVPSGLPRRVRTLMIL---HNQITGIGREDFATTYFLEELNLSYNRITSPQ 449
Query: 176 LAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
+ F L+LLR+LDL N L +P N+ L + +N+L + A G
Sbjct: 450 VHRDAFRKLRLLRSLDLSGNRLHTLPPGLPR---NVHVLKVKRNELAALARGALVG 502
Score = 55.6 bits (128), Expect = 2e-06
Identities = 58/204 (28%), Positives = 87/204 (42%), Gaps = 13/204 (6%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINN--ISDNAFENXXXXXXXXXDRNKLKN 151
L L N+++ I S L L+ L L +N++ + + + AFE+ NKL
Sbjct: 130 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTL 189
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ--IPDNTFSDCF 209
P L N LI +D + N L + G+ F LR++ L N L+ +PDN F+
Sbjct: 190 APRFLPN---ALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSS 246
Query: 210 NLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
N+E L LS N LR + + ++ AFS L +L LYL N
Sbjct: 247 NVEVLILSSNFLRHV---PKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYL 303
Query: 270 --PSLPSRTLDYMPKLTIVKLSGN 291
L + T + L + LS N
Sbjct: 304 TDEGLDNETFWKLSSLEYLDLSSN 327
>AL445183-4|CAH72591.1| 661|Homo sapiens podocan protein.
Length = 661
Score = 77.8 bits (183), Expect = 4e-13
Identities = 68/206 (33%), Positives = 99/206 (48%), Gaps = 13/206 (6%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYT--LPEKLFANNTFLETIDISNNRVVY 80
L LQ N LE+I E + +L ++L NN L + LPEK F + T L + ++NN++
Sbjct: 149 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTL 208
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLK-NLQILKLSDNKINN--ISDNAFENXX 137
P FL +L +D + N + I TF K NL+ + L +NK+ + + DN F
Sbjct: 209 AP--RFLP-NALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSS 265
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
N L+++P L L L L NN L + F L LR L L+ N L
Sbjct: 266 NVEVLILSSNFLRHVPKHL---PPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYL 322
Query: 198 SQ--IPDNTFSDCFNLEKLDLSKNKL 221
+ + + TF +LE LDLS N L
Sbjct: 323 TDEGLDNETFWKLSSLEYLDLSSNNL 348
Score = 69.3 bits (162), Expect = 1e-10
Identities = 62/210 (29%), Positives = 101/210 (48%), Gaps = 15/210 (7%)
Query: 20 LKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYT--LPEKLFANNTFLETIDISNNR 77
L L L+ N LE+I AF+ L + L NNYL L + F + LE +D+S+N
Sbjct: 288 LYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNN 347
Query: 78 VVYVPSDSFLGL-YSLQILDLSKNKIQNIQ-NGTFSLKNLQILKLSDNKI--NNISDNAF 133
+ VP+ GL SL +L L KN I+++ N +++L+ L L N++ I AF
Sbjct: 348 LSRVPA----GLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAF 403
Query: 134 ENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLK 193
+ N L+ +P+ L ++ L+ L +N + + +F + L L+L
Sbjct: 404 QGLKRLHTVHLYNNALERVPSGLPRRVRTLMIL---HNQITGIGREDFATTYFLEELNLS 460
Query: 194 ENALS--QIPDNTFSDCFNLEKLDLSKNKL 221
N ++ Q+ + F L LDLS N+L
Sbjct: 461 YNRITSPQVHRDAFRKLRLLRSLDLSGNRL 490
Score = 69.3 bits (162), Expect = 1e-10
Identities = 59/212 (27%), Positives = 101/212 (47%), Gaps = 12/212 (5%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F+ L L T+ L N LE + S + L + +N + + + FA FLE +++
Sbjct: 403 FQGLKRLHTVHLYNNALERVPSGLPRRVRTLM---ILHNQITGIGREDFATTYFLEELNL 459
Query: 74 SNNRVV--YVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDN 131
S NR+ V D+F L L+ LDLS N++ + G +N+ +LK+ N++ ++
Sbjct: 460 SYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGL--PRNVHVLKVKRNELAALARG 517
Query: 132 AFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRN 189
A N+L++ + + + +L L LD++ N L + ESL+ L
Sbjct: 518 ALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLY- 576
Query: 190 LDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
L+ N +S +P N F NL+ + L NKL
Sbjct: 577 --LQNNKISAVPANAFDSTPNLKGIFLRFNKL 606
Score = 67.3 bits (157), Expect = 6e-10
Identities = 67/236 (28%), Positives = 106/236 (44%), Gaps = 16/236 (6%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYL--EEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+N +E +P G F L +L+ L LQ NYL E +D+E F L ++DLS+N L +P
Sbjct: 295 NNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAG 354
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI--QNIQNGTF-SLKNLQI 117
L + L + + N + V ++ + SL+ L L N++ Q I F LK L
Sbjct: 355 LPRS---LVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHT 411
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMS-- 175
+ L +N + + N++ I + F L L+LS N + S
Sbjct: 412 VHLYNNALERVPSGLPRRVRTLMIL---HNQITGIGREDFATTYFLEELNLSYNRITSPQ 468
Query: 176 LAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYG 231
+ F L+LLR+LDL N L +P N+ L + +N+L + A G
Sbjct: 469 VHRDAFRKLRLLRSLDLSGNRLHTLPPGLPR---NVHVLKVKRNELAALARGALVG 521
Score = 55.6 bits (128), Expect = 2e-06
Identities = 58/204 (28%), Positives = 87/204 (42%), Gaps = 13/204 (6%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINN--ISDNAFENXXXXXXXXXDRNKLKN 151
L L N+++ I S L L+ L L +N++ + + + AFE+ NKL
Sbjct: 149 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTL 208
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ--IPDNTFSDCF 209
P L N LI +D + N L + G+ F LR++ L N L+ +PDN F+
Sbjct: 209 APRFLPN---ALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSS 265
Query: 210 NLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
N+E L LS N LR + + ++ AFS L +L LYL N
Sbjct: 266 NVEVLILSSNFLRHV---PKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYL 322
Query: 270 --PSLPSRTLDYMPKLTIVKLSGN 291
L + T + L + LS N
Sbjct: 323 TDEGLDNETFWKLSSLEYLDLSSN 346
>BC063114-1|AAH63114.1| 384|Homo sapiens ASPN protein protein.
Length = 384
Score = 77.0 bits (181), Expect = 7e-13
Identities = 57/229 (24%), Positives = 107/229 (46%), Gaps = 9/229 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ + F+ L +L L L N L +I +AF +TKKL + LS+N L +P L
Sbjct: 115 NNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLP 174
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQN--IQNGTFSLKNLQILKL 120
+ L + I N+V + D+F G+ +L +L++S N + N I+ G F + +++
Sbjct: 175 KS---LAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRI 231
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
++ K+ ++ D NK+ + + F K L L L NN + +
Sbjct: 232 AEAKLTSVPKGL---PPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGS 288
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
++ +R + L+ N L +IP + L+ + L N + + + F
Sbjct: 289 LANIPRVREIHLENNKLKKIPSG-LPELKYLQIIFLHSNSIARVGVNDF 336
Score = 71.3 bits (167), Expect = 3e-11
Identities = 57/207 (27%), Positives = 100/207 (48%), Gaps = 10/207 (4%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
+ L LQ N ++EI F L+ + L+NN L + K F L + +S+N++
Sbjct: 109 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 168
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKN-LQILKLSDNKINN--ISDNAFENXX 137
+P + L L+I +NK++ IQ TF N L +L++S N ++N I AFE
Sbjct: 169 IPLNLPKSLAELRI---HENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVT 225
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
+ KL ++P L L+ L L N + ++ +F+ K L+ L L N +
Sbjct: 226 VFHIRIAEA-KLTSVPKGL---PPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKI 281
Query: 198 SQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ I + + ++ + ++ L NKL+ I
Sbjct: 282 TDIENGSLANIPRVREIHLENNKLKKI 308
Score = 43.6 bits (98), Expect = 0.008
Identities = 31/85 (36%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
NK+K I F L L L L+NN L + F + K LR L L N LS+IP N
Sbjct: 116 NKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPK 175
Query: 207 DCFNLEKLDLSKNKLRFINITAFYG 231
+L +L + +NK++ I F G
Sbjct: 176 ---SLAELRIHENKVKKIQKDTFKG 197
Score = 43.2 bits (97), Expect = 0.010
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Query: 90 YSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNK 148
+ ++LDL NKI+ I+ F L +L L L++NK+ I AF N+
Sbjct: 106 FDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQ 165
Query: 149 LKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
L IP N K L L + N + + F+ + L L++ N L
Sbjct: 166 LSEIP---LNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPL 211
Score = 37.9 bits (84), Expect = 0.39
Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 3/105 (2%)
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
R LDL+ N + +I +N F +L L L+ NKL I+ AF E
Sbjct: 109 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 168
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNP 292
+ ++ K+L L + N + T M L ++++S NP
Sbjct: 169 I---PLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANP 210
Score = 36.3 bits (80), Expect = 1.2
Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 3/77 (3%)
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSML 256
L+ +P N F+ LDL NK++ I F G ++H KAF
Sbjct: 97 LTSVPTNI---PFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTT 153
Query: 257 KNLTTLYLDGNMFPSLP 273
K L LYL N +P
Sbjct: 154 KKLRRLYLSHNQLSEIP 170
>AY358329-1|AAQ88695.1| 379|Homo sapiens ASPN protein.
Length = 379
Score = 77.0 bits (181), Expect = 7e-13
Identities = 57/229 (24%), Positives = 107/229 (46%), Gaps = 9/229 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ + F+ L +L L L N L +I +AF +TKKL + LS+N L +P L
Sbjct: 110 NNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLP 169
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQN--IQNGTFSLKNLQILKL 120
+ L + I N+V + D+F G+ +L +L++S N + N I+ G F + +++
Sbjct: 170 KS---LAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRI 226
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
++ K+ ++ D NK+ + + F K L L L NN + +
Sbjct: 227 AEAKLTSVPKGL---PPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGS 283
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
++ +R + L+ N L +IP + L+ + L N + + + F
Sbjct: 284 LANIPRVREIHLENNKLKKIPSG-LPELKYLQIIFLHSNSIARVGVNDF 331
Score = 71.3 bits (167), Expect = 3e-11
Identities = 57/207 (27%), Positives = 100/207 (48%), Gaps = 10/207 (4%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
+ L LQ N ++EI F L+ + L+NN L + K F L + +S+N++
Sbjct: 104 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 163
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKN-LQILKLSDNKINN--ISDNAFENXX 137
+P + L L+I +NK++ IQ TF N L +L++S N ++N I AFE
Sbjct: 164 IPLNLPKSLAELRI---HENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVT 220
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
+ KL ++P L L+ L L N + ++ +F+ K L+ L L N +
Sbjct: 221 VFHIRIAEA-KLTSVPKGL---PPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKI 276
Query: 198 SQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ I + + ++ + ++ L NKL+ I
Sbjct: 277 TDIENGSLANIPRVREIHLENNKLKKI 303
Score = 43.6 bits (98), Expect = 0.008
Identities = 31/85 (36%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
NK+K I F L L L L+NN L + F + K LR L L N LS+IP N
Sbjct: 111 NKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPK 170
Query: 207 DCFNLEKLDLSKNKLRFINITAFYG 231
+L +L + +NK++ I F G
Sbjct: 171 ---SLAELRIHENKVKKIQKDTFKG 192
Score = 43.2 bits (97), Expect = 0.010
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Query: 90 YSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNK 148
+ ++LDL NKI+ I+ F L +L L L++NK+ I AF N+
Sbjct: 101 FDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQ 160
Query: 149 LKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
L IP N K L L + N + + F+ + L L++ N L
Sbjct: 161 LSEIP---LNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPL 206
Score = 37.9 bits (84), Expect = 0.39
Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 3/105 (2%)
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
R LDL+ N + +I +N F +L L L+ NKL I+ AF E
Sbjct: 104 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 163
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNP 292
+ ++ K+L L + N + T M L ++++S NP
Sbjct: 164 I---PLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANP 205
Score = 36.3 bits (80), Expect = 1.2
Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 3/77 (3%)
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSML 256
L+ +P N F+ LDL NK++ I F G ++H KAF
Sbjct: 92 LTSVPTNI---PFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTT 148
Query: 257 KNLTTLYLDGNMFPSLP 273
K L LYL N +P
Sbjct: 149 KKLRRLYLSHNQLSEIP 165
>AY029191-1|AAK31800.1| 381|Homo sapiens periodontal ligament
associated protein 1 protein.
Length = 381
Score = 77.0 bits (181), Expect = 7e-13
Identities = 57/229 (24%), Positives = 107/229 (46%), Gaps = 9/229 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ + F+ L +L L L N L +I +AF +TKKL + LS+N L +P L
Sbjct: 112 NNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLP 171
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQN--IQNGTFSLKNLQILKL 120
+ L + I N+V + D+F G+ +L +L++S N + N I+ G F + +++
Sbjct: 172 KS---LAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRI 228
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
++ K+ ++ D NK+ + + F K L L L NN + +
Sbjct: 229 AEAKLTSVPKGL---PPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGS 285
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
++ +R + L+ N L +IP + L+ + L N + + + F
Sbjct: 286 LANIPRVREIHLENNKLKKIPSG-LPELKYLQIIFLHSNSIARVGVNDF 333
Score = 71.3 bits (167), Expect = 3e-11
Identities = 57/207 (27%), Positives = 100/207 (48%), Gaps = 10/207 (4%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
+ L LQ N ++EI F L+ + L+NN L + K F L + +S+N++
Sbjct: 106 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 165
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKN-LQILKLSDNKINN--ISDNAFENXX 137
+P + L L+I +NK++ IQ TF N L +L++S N ++N I AFE
Sbjct: 166 IPLNLPKSLAELRI---HENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVT 222
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
+ KL ++P L L+ L L N + ++ +F+ K L+ L L N +
Sbjct: 223 VFHIRIAEA-KLTSVPKGL---PPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKI 278
Query: 198 SQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ I + + ++ + ++ L NKL+ I
Sbjct: 279 TDIENGSLANIPRVREIHLENNKLKKI 305
Score = 43.6 bits (98), Expect = 0.008
Identities = 31/85 (36%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
NK+K I F L L L L+NN L + F + K LR L L N LS+IP N
Sbjct: 113 NKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPK 172
Query: 207 DCFNLEKLDLSKNKLRFINITAFYG 231
+L +L + +NK++ I F G
Sbjct: 173 ---SLAELRIHENKVKKIQKDTFKG 194
Score = 43.2 bits (97), Expect = 0.010
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Query: 90 YSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNK 148
+ ++LDL NKI+ I+ F L +L L L++NK+ I AF N+
Sbjct: 103 FDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQ 162
Query: 149 LKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
L IP N K L L + N + + F+ + L L++ N L
Sbjct: 163 LSEIP---LNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPL 208
Score = 37.9 bits (84), Expect = 0.39
Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 3/105 (2%)
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
R LDL+ N + +I +N F +L L L+ NKL I+ AF E
Sbjct: 106 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 165
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNP 292
+ ++ K+L L + N + T M L ++++S NP
Sbjct: 166 I---PLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANP 207
Score = 36.3 bits (80), Expect = 1.2
Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 3/77 (3%)
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSML 256
L+ +P N F+ LDL NK++ I F G ++H KAF
Sbjct: 94 LTSVPTNI---PFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTT 150
Query: 257 KNLTTLYLDGNMFPSLP 273
K L LYL N +P
Sbjct: 151 KKLRRLYLSHNQLSEIP 167
>AL137848-5|CAI16697.1| 380|Homo sapiens asporin (LRR class 1)
protein.
Length = 380
Score = 77.0 bits (181), Expect = 7e-13
Identities = 57/229 (24%), Positives = 107/229 (46%), Gaps = 9/229 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ + F+ L +L L L N L +I +AF +TKKL + LS+N L +P L
Sbjct: 111 NNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLP 170
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQN--IQNGTFSLKNLQILKL 120
+ L + I N+V + D+F G+ +L +L++S N + N I+ G F + +++
Sbjct: 171 KS---LAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRI 227
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
++ K+ ++ D NK+ + + F K L L L NN + +
Sbjct: 228 AEAKLTSVPKGL---PPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGS 284
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
++ +R + L+ N L +IP + L+ + L N + + + F
Sbjct: 285 LANIPRVREIHLENNKLKKIPSG-LPELKYLQIIFLHSNSIARVGVNDF 332
Score = 71.3 bits (167), Expect = 3e-11
Identities = 57/207 (27%), Positives = 100/207 (48%), Gaps = 10/207 (4%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
+ L LQ N ++EI F L+ + L+NN L + K F L + +S+N++
Sbjct: 105 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 164
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKN-LQILKLSDNKINN--ISDNAFENXX 137
+P + L L+I +NK++ IQ TF N L +L++S N ++N I AFE
Sbjct: 165 IPLNLPKSLAELRI---HENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVT 221
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
+ KL ++P L L+ L L N + ++ +F+ K L+ L L N +
Sbjct: 222 VFHIRIAEA-KLTSVPKGL---PPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKI 277
Query: 198 SQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ I + + ++ + ++ L NKL+ I
Sbjct: 278 TDIENGSLANIPRVREIHLENNKLKKI 304
Score = 43.6 bits (98), Expect = 0.008
Identities = 31/85 (36%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
NK+K I F L L L L+NN L + F + K LR L L N LS+IP N
Sbjct: 112 NKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPK 171
Query: 207 DCFNLEKLDLSKNKLRFINITAFYG 231
+L +L + +NK++ I F G
Sbjct: 172 ---SLAELRIHENKVKKIQKDTFKG 193
Score = 43.2 bits (97), Expect = 0.010
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Query: 90 YSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNK 148
+ ++LDL NKI+ I+ F L +L L L++NK+ I AF N+
Sbjct: 102 FDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQ 161
Query: 149 LKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
L IP N K L L + N + + F+ + L L++ N L
Sbjct: 162 LSEIP---LNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPL 207
Score = 37.9 bits (84), Expect = 0.39
Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 3/105 (2%)
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
R LDL+ N + +I +N F +L L L+ NKL I+ AF E
Sbjct: 105 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 164
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNP 292
+ ++ K+L L + N + T M L ++++S NP
Sbjct: 165 I---PLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANP 206
Score = 36.3 bits (80), Expect = 1.2
Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 3/77 (3%)
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSML 256
L+ +P N F+ LDL NK++ I F G ++H KAF
Sbjct: 93 LTSVPTNI---PFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTT 149
Query: 257 KNLTTLYLDGNMFPSLP 273
K L LYL N +P
Sbjct: 150 KKLRRLYLSHNQLSEIP 166
>AF316824-1|AAK35161.1| 379|Homo sapiens asporin precursor protein.
Length = 379
Score = 77.0 bits (181), Expect = 7e-13
Identities = 57/229 (24%), Positives = 107/229 (46%), Gaps = 9/229 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ + F+ L +L L L N L +I +AF +TKKL + LS+N L +P L
Sbjct: 110 NNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLP 169
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQN--IQNGTFSLKNLQILKL 120
+ L + I N+V + D+F G+ +L +L++S N + N I+ G F + +++
Sbjct: 170 KS---LAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRI 226
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
++ K+ ++ D NK+ + + F K L L L NN + +
Sbjct: 227 AEAKLTSVPKGL---PPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGS 283
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
++ +R + L+ N L +IP + L+ + L N + + + F
Sbjct: 284 LANIPRVREIHLENNKLKKIPSG-LPELKYLQIIFLHSNSIARVGVNDF 331
Score = 71.3 bits (167), Expect = 3e-11
Identities = 57/207 (27%), Positives = 100/207 (48%), Gaps = 10/207 (4%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
+ L LQ N ++EI F L+ + L+NN L + K F L + +S+N++
Sbjct: 104 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 163
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKN-LQILKLSDNKINN--ISDNAFENXX 137
+P + L L+I +NK++ IQ TF N L +L++S N ++N I AFE
Sbjct: 164 IPLNLPKSLAELRI---HENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVT 220
Query: 138 XXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
+ KL ++P L L+ L L N + ++ +F+ K L+ L L N +
Sbjct: 221 VFHIRIAEA-KLTSVPKGL---PPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKI 276
Query: 198 SQIPDNTFSDCFNLEKLDLSKNKLRFI 224
+ I + + ++ + ++ L NKL+ I
Sbjct: 277 TDIENGSLANIPRVREIHLENNKLKKI 303
Score = 43.6 bits (98), Expect = 0.008
Identities = 31/85 (36%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
NK+K I F L L L L+NN L + F + K LR L L N LS+IP N
Sbjct: 111 NKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPK 170
Query: 207 DCFNLEKLDLSKNKLRFINITAFYG 231
+L +L + +NK++ I F G
Sbjct: 171 ---SLAELRIHENKVKKIQKDTFKG 192
Score = 43.2 bits (97), Expect = 0.010
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Query: 90 YSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNK 148
+ ++LDL NKI+ I+ F L +L L L++NK+ I AF N+
Sbjct: 101 FDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQ 160
Query: 149 LKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
L IP N K L L + N + + F+ + L L++ N L
Sbjct: 161 LSEIP---LNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPL 206
Score = 37.9 bits (84), Expect = 0.39
Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 3/105 (2%)
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYE 247
R LDL+ N + +I +N F +L L L+ NKL I+ AF E
Sbjct: 104 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 163
Query: 248 VHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNP 292
+ ++ K+L L + N + T M L ++++S NP
Sbjct: 164 I---PLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANP 205
Score = 36.3 bits (80), Expect = 1.2
Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 3/77 (3%)
Query: 197 LSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSML 256
L+ +P N F+ LDL NK++ I F G ++H KAF
Sbjct: 92 LTSVPTNI---PFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTT 148
Query: 257 KNLTTLYLDGNMFPSLP 273
K L LYL N +P
Sbjct: 149 KKLRRLYLSHNQLSEIP 165
>BC114621-1|AAI14622.1| 977|Homo sapiens SLIT and NTRK-like family,
member 3 protein.
Length = 977
Score = 76.2 bits (179), Expect = 1e-12
Identities = 58/212 (27%), Positives = 94/212 (44%), Gaps = 3/212 (1%)
Query: 146 RNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTF 205
RN ++ + T F +L + ++L NN L + F LK+L+ L L EN L ++TF
Sbjct: 86 RNSMRKLYTNSFLHLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHENKLDVFRNDTF 145
Query: 206 SDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLD 265
+LE L N ++ I AF + F + +LT L L
Sbjct: 146 LGLESLEYLQADYNVIKRIESGAFRNLSKLRVLILNDNLIPMLPTNLFKAV-SLTHLDLR 204
Query: 266 GNMFPSLPSR-TLDYMPK-LTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSP 323
GN L R LD++ + L ++L NPW+C C + + +W+ TC +P
Sbjct: 205 GNRLKVLFYRGMLDHIGRSLMELQLEENPWNCTCEIVQLKSWLERIPYTALVGDITCETP 264
Query: 324 WYLEGHFLKKLKFPELCAGQWASMVNLSPRLP 355
++ G L++++ ELC S V S +P
Sbjct: 265 FHFHGKDLREIRKTELCPLLSDSEVEASLGIP 296
Score = 60.9 bits (141), Expect = 5e-08
Identities = 35/113 (30%), Positives = 60/113 (53%), Gaps = 1/113 (0%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
L LQRN + ++ + +F ++L NN L + F L+ + + N++
Sbjct: 82 LYLQRNSMRKLYTNSFLHLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHENKLDVFR 141
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFE 134
+D+FLGL SL+ L N I+ I++G F +L L++L L+DN I + N F+
Sbjct: 142 NDTFLGLESLEYLQADYNVIKRIESGAFRNLSKLRVLILNDNLIPMLPTNLFK 194
Score = 56.4 bits (130), Expect = 1e-06
Identities = 50/174 (28%), Positives = 81/174 (46%), Gaps = 10/174 (5%)
Query: 31 EEIDSEAFTST-----KKLFHVDLSNNYLYTLPEKL-FANNTFLETIDISNNRVVYVPSD 84
EEID F + LFH+ + + + F + F + ++ R +Y ++
Sbjct: 38 EEIDEPCFDPCYCEVKESLFHIHCDSKGFTNISQITEFWSRPFKLYLQRNSMRKLY--TN 95
Query: 85 SFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXX 143
SFL L + ++L N +Q+IQ G F+ LK L+ L L +NK++ ++ F
Sbjct: 96 SFLHLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHENKLDVFRNDTFLGLESLEYLQ 155
Query: 144 XDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
D N +K I + F NL L L L N+NL+ + L +LDL+ N L
Sbjct: 156 ADYNVIKRIESGAFRNLSKLRVLIL-NDNLIPMLPTNLFKAVSLTHLDLRGNRL 208
Score = 56.0 bits (129), Expect = 1e-06
Identities = 46/172 (26%), Positives = 79/172 (45%), Gaps = 8/172 (4%)
Query: 2 FDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKL 61
F+N E LP + N K L L N +++I F + L + L NN + + +
Sbjct: 397 FNNISELLPRPL-----NAKKLYLSSNLIQKIYRSDFWNFSSLDLLHLGNNRISYVQDGA 451
Query: 62 FANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSL-KNLQILKL 120
F N L+++ ++ N + + F GL SL L N I+ IQ FSL NL++L L
Sbjct: 452 FINLPNLKSLFLNGNDIEKLTPGMFRGLQSLHYLYFEFNVIREIQPAAFSLMPNLKLLFL 511
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQ-LFNNLKCLIFLDLSNN 171
++N + + +AF +N +P + +L ++ +DL+ N
Sbjct: 512 NNNLLRTLPTDAFAGTSLARLNLR-KNYFLYLPVAGVLEHLNAIVQIDLNEN 562
Score = 52.0 bits (119), Expect = 2e-05
Identities = 57/228 (25%), Positives = 86/228 (37%), Gaps = 26/228 (11%)
Query: 114 NLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
N + L LS N I I + F N N++ + F NL L L L+ N++
Sbjct: 409 NAKKLYLSSNLIQKIYRSDFWNFSSLDLLHLGNNRISYVQDGAFINLPNLKSLFLNGNDI 468
Query: 174 MSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXX 233
L F L+ L L + N + +I FS NL+ L L+ N LR + AF G
Sbjct: 469 EKLTPGMFRGLQSLHYLYFEFNVIREIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAGT- 527
Query: 234 XXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLP-SRTLDYMPKLTIVKLSGNP 292
+L L L N F LP + L+++ + + L+ NP
Sbjct: 528 ------------------------SLARLNLRKNYFLYLPVAGVLEHLNAIVQIDLNENP 563
Query: 293 WHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPELC 340
W C C + W+ C SP L ++ ++ LC
Sbjct: 564 WDCTCDLVPFKQWIETISSVSVVGDVLCRSPENLTHRDVRTIELEVLC 611
>BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like family,
member 4 protein.
Length = 837
Score = 76.2 bits (179), Expect = 1e-12
Identities = 55/195 (28%), Positives = 81/195 (41%), Gaps = 2/195 (1%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N L + F N + L L NN L ++ G F L L+ L L N L + +TF
Sbjct: 69 NFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFL 128
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
NLE L N +++I AF + F +LT L + G
Sbjct: 129 GIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFA-SLTHLDIRG 187
Query: 267 NMFPSLPS-RTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWY 325
N LP L+++ ++ ++L NPW+C C L + AW+ I+ C +P
Sbjct: 188 NRIQKLPYIGVLEHIGRVVELQLEDNPWNCSCDLLPLKAWLENMPYNIYIGEAICETPSD 247
Query: 326 LEGHFLKKLKFPELC 340
L G LK+ ELC
Sbjct: 248 LYGRLLKETNKQELC 262
Score = 70.9 bits (166), Expect = 4e-11
Identities = 56/195 (28%), Positives = 78/195 (40%), Gaps = 2/195 (1%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N +K++ F + + L L L +N + + G F +L LR L L N + ++ FS
Sbjct: 387 NSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFS 446
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
NL+ L L N ++ I+ F + FS L L L
Sbjct: 447 GLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP-LARLNLRN 505
Query: 267 NMFPSLP-SRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWY 325
N F LP S LD + LT + L GNPW C C + + WV I C +P
Sbjct: 506 NKFMYLPVSGVLDQLQSLTQIDLEGNPWDCTCDLVALKLWVEKLSDGIVVKELKCETPVQ 565
Query: 326 LEGHFLKKLKFPELC 340
LK LK LC
Sbjct: 566 FANIELKSLKNEILC 580
Score = 66.1 bits (154), Expect = 1e-09
Identities = 44/156 (28%), Positives = 79/156 (50%), Gaps = 3/156 (1%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNR 77
+N K L + N ++++D FT + L + L +N + + +F N T L + ++ N+
Sbjct: 377 LNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQ 436
Query: 78 VVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENX 136
+ + + F GL++LQ L L N I+ I GTF S+ NLQ+L L++N + ++ F
Sbjct: 437 IERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGA 496
Query: 137 XXXXXXXXDRNKLKNIPTQ-LFNNLKCLIFLDLSNN 171
+ NK +P + + L+ L +DL N
Sbjct: 497 PLARLNLRN-NKFMYLPVSGVLDQLQSLTQIDLEGN 531
Score = 62.9 bits (146), Expect = 1e-08
Identities = 37/127 (29%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Query: 8 YLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTF 67
Y P + N L Q N+L + F + + L NN L + F +
Sbjct: 49 YRPNQLKPPWSNFYHLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSA 108
Query: 68 LETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKIN 126
L+ + ++NN + + +D+FLG+ +L+ L N I+ I+ G F+ L L++L L+DN I+
Sbjct: 109 LKQLHLNNNELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLIS 168
Query: 127 NISDNAF 133
+ DN F
Sbjct: 169 FLPDNIF 175
Score = 53.6 bits (123), Expect = 7e-06
Identities = 34/134 (25%), Positives = 66/134 (49%), Gaps = 2/134 (1%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
L ++ N I+++ F+ + L +L L N+I I + F N + N+++ +
Sbjct: 382 LHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLY 441
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
++F+ L L +L L N + ++ F+S+ L+ L L N L +P FS L +
Sbjct: 442 PEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGA-PLAR 500
Query: 214 LDLSKNKLRFINIT 227
L+L NK ++ ++
Sbjct: 501 LNLRNNKFMYLPVS 514
Score = 53.2 bits (122), Expect = 1e-05
Identities = 35/98 (35%), Positives = 53/98 (54%), Gaps = 2/98 (2%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N +E L IF L NL+ L L+ N ++EI + F S L + L+NN L +LP +F+
Sbjct: 435 NQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFS 494
Query: 64 NNTFLETIDISNNRVVYVPSDSFLG-LYSLQILDLSKN 100
L +++ NN+ +Y+P L L SL +DL N
Sbjct: 495 GAP-LARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 531
Score = 48.4 bits (110), Expect = 3e-04
Identities = 34/129 (26%), Positives = 58/129 (44%), Gaps = 2/129 (1%)
Query: 95 LDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
L+ N + + TF + + L L +NK+ NI AF + N+LK +
Sbjct: 64 LNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILR 123
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
F ++ L +L N + + F L L+ L L +N +S +PDN F +L
Sbjct: 124 ADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFA-SLTH 182
Query: 214 LDLSKNKLR 222
LD+ N+++
Sbjct: 183 LDIRGNRIQ 191
Score = 43.6 bits (98), Expect = 0.008
Identities = 26/103 (25%), Positives = 51/103 (49%), Gaps = 1/103 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ + GG F L LK L L N L+ + ++ F + L ++ N + + F
Sbjct: 92 NNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLGIENLEYLQADYNLIKYIERGAF 151
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI 105
L+ + +++N + ++P D+ SL LD+ N+IQ +
Sbjct: 152 NKLHKLKVLILNDNLISFLP-DNIFRFASLTHLDIRGNRIQKL 193
Score = 37.9 bits (84), Expect = 0.39
Identities = 23/80 (28%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ L F + NL+ L+ N ++ I+ AF KL + L++N + LP+ +F
Sbjct: 116 NNELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIF 175
Query: 63 ANNTFLETIDISNNRVVYVP 82
L +DI NR+ +P
Sbjct: 176 -RFASLTHLDIRGNRIQKLP 194
Score = 37.9 bits (84), Expect = 0.39
Identities = 27/111 (24%), Positives = 52/111 (46%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F L L L N + I + F + L + L+ N + L ++F+ L+ + +
Sbjct: 397 FTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYL 456
Query: 74 SNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNK 124
N + + + +F + +LQ+L L+ N ++++ FS L L L +NK
Sbjct: 457 EYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLARLNLRNNK 507
>AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein.
Length = 837
Score = 76.2 bits (179), Expect = 1e-12
Identities = 55/195 (28%), Positives = 81/195 (41%), Gaps = 2/195 (1%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N L + F N + L L NN L ++ G F L L+ L L N L + +TF
Sbjct: 69 NFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFL 128
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
NLE L N +++I AF + F +LT L + G
Sbjct: 129 GIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFA-SLTHLDIRG 187
Query: 267 NMFPSLPS-RTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWY 325
N LP L+++ ++ ++L NPW+C C L + AW+ I+ C +P
Sbjct: 188 NRIQKLPYIGVLEHIGRVVELQLEDNPWNCSCDLLPLKAWLENMPYNIYIGEAICETPSD 247
Query: 326 LEGHFLKKLKFPELC 340
L G LK+ ELC
Sbjct: 248 LYGRLLKETNKQELC 262
Score = 70.9 bits (166), Expect = 4e-11
Identities = 56/195 (28%), Positives = 78/195 (40%), Gaps = 2/195 (1%)
Query: 147 NKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFS 206
N +K++ F + + L L L +N + + G F +L LR L L N + ++ FS
Sbjct: 387 NSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFS 446
Query: 207 DCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDG 266
NL+ L L N ++ I+ F + FS L L L
Sbjct: 447 GLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP-LARLNLRN 505
Query: 267 NMFPSLP-SRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWY 325
N F LP S LD + LT + L GNPW C C + + WV I C +P
Sbjct: 506 NKFMYLPVSGVLDQLQSLTQIDLEGNPWDCTCDLVALKLWVEKLSDGIVVKELKCETPVQ 565
Query: 326 LEGHFLKKLKFPELC 340
LK LK LC
Sbjct: 566 FANIELKSLKNEILC 580
Score = 66.1 bits (154), Expect = 1e-09
Identities = 44/156 (28%), Positives = 79/156 (50%), Gaps = 3/156 (1%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNR 77
+N K L + N ++++D FT + L + L +N + + +F N T L + ++ N+
Sbjct: 377 LNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQ 436
Query: 78 VVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENX 136
+ + + F GL++LQ L L N I+ I GTF S+ NLQ+L L++N + ++ F
Sbjct: 437 IERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGA 496
Query: 137 XXXXXXXXDRNKLKNIPTQ-LFNNLKCLIFLDLSNN 171
+ NK +P + + L+ L +DL N
Sbjct: 497 PLARLNLRN-NKFMYLPVSGVLDQLQSLTQIDLEGN 531
Score = 62.9 bits (146), Expect = 1e-08
Identities = 37/127 (29%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Query: 8 YLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTF 67
Y P + N L Q N+L + F + + L NN L + F +
Sbjct: 49 YRPNQLKPPWSNFYHLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSA 108
Query: 68 LETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKIN 126
L+ + ++NN + + +D+FLG+ +L+ L N I+ I+ G F+ L L++L L+DN I+
Sbjct: 109 LKQLHLNNNELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLIS 168
Query: 127 NISDNAF 133
+ DN F
Sbjct: 169 FLPDNIF 175
Score = 53.6 bits (123), Expect = 7e-06
Identities = 34/134 (25%), Positives = 66/134 (49%), Gaps = 2/134 (1%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
L ++ N I+++ F+ + L +L L N+I I + F N + N+++ +
Sbjct: 382 LHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLY 441
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
++F+ L L +L L N + ++ F+S+ L+ L L N L +P FS L +
Sbjct: 442 PEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGA-PLAR 500
Query: 214 LDLSKNKLRFINIT 227
L+L NK ++ ++
Sbjct: 501 LNLRNNKFMYLPVS 514
Score = 53.2 bits (122), Expect = 1e-05
Identities = 35/98 (35%), Positives = 53/98 (54%), Gaps = 2/98 (2%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N +E L IF L NL+ L L+ N ++EI + F S L + L+NN L +LP +F+
Sbjct: 435 NQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFS 494
Query: 64 NNTFLETIDISNNRVVYVPSDSFLG-LYSLQILDLSKN 100
L +++ NN+ +Y+P L L SL +DL N
Sbjct: 495 GAP-LARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 531
Score = 48.4 bits (110), Expect = 3e-04
Identities = 34/129 (26%), Positives = 58/129 (44%), Gaps = 2/129 (1%)
Query: 95 LDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIP 153
L+ N + + TF + + L L +NK+ NI AF + N+LK +
Sbjct: 64 LNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILR 123
Query: 154 TQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEK 213
F ++ L +L N + + F L L+ L L +N +S +PDN F +L
Sbjct: 124 ADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFA-SLTH 182
Query: 214 LDLSKNKLR 222
LD+ N+++
Sbjct: 183 LDIRGNRIQ 191
Score = 43.6 bits (98), Expect = 0.008
Identities = 26/103 (25%), Positives = 51/103 (49%), Gaps = 1/103 (0%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ + GG F L LK L L N L+ + ++ F + L ++ N + + F
Sbjct: 92 NNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLGIENLEYLQADYNLIKYIERGAF 151
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNI 105
L+ + +++N + ++P D+ SL LD+ N+IQ +
Sbjct: 152 NKLHKLKVLILNDNLISFLP-DNIFRFASLTHLDIRGNRIQKL 193
Score = 37.9 bits (84), Expect = 0.39
Identities = 23/80 (28%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ L F + NL+ L+ N ++ I+ AF KL + L++N + LP+ +F
Sbjct: 116 NNELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIF 175
Query: 63 ANNTFLETIDISNNRVVYVP 82
L +DI NR+ +P
Sbjct: 176 -RFASLTHLDIRGNRIQKLP 194
Score = 37.9 bits (84), Expect = 0.39
Identities = 27/111 (24%), Positives = 52/111 (46%)
Query: 14 FESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDI 73
F L L L N + I + F + L + L+ N + L ++F+ L+ + +
Sbjct: 397 FTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYL 456
Query: 74 SNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNK 124
N + + + +F + +LQ+L L+ N ++++ FS L L L +NK
Sbjct: 457 EYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLARLNLRNNK 507
>AB020655-1|BAA74871.2| 988|Homo sapiens KIAA0848 protein protein.
Length = 988
Score = 76.2 bits (179), Expect = 1e-12
Identities = 58/212 (27%), Positives = 94/212 (44%), Gaps = 3/212 (1%)
Query: 146 RNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTF 205
RN ++ + T F +L + ++L NN L + F LK+L+ L L EN L ++TF
Sbjct: 97 RNSMRKLYTNSFLHLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHENKLDVFRNDTF 156
Query: 206 SDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLD 265
+LE L N ++ I AF + F + +LT L L
Sbjct: 157 LGLESLEYLQADYNVIKRIESGAFRNLSKLRVLILNDNLIPMLPTNLFKAV-SLTHLDLR 215
Query: 266 GNMFPSLPSR-TLDYMPK-LTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSP 323
GN L R LD++ + L ++L NPW+C C + + +W+ TC +P
Sbjct: 216 GNRLKVLFYRGMLDHIGRSLMELQLEENPWNCTCEIVQLKSWLERIPYTALVGDITCETP 275
Query: 324 WYLEGHFLKKLKFPELCAGQWASMVNLSPRLP 355
++ G L++++ ELC S V S +P
Sbjct: 276 FHFHGKDLREIRKTELCPLLSDSEVEASLGIP 307
Score = 60.9 bits (141), Expect = 5e-08
Identities = 35/113 (30%), Positives = 60/113 (53%), Gaps = 1/113 (0%)
Query: 23 LRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVP 82
L LQRN + ++ + +F ++L NN L + F L+ + + N++
Sbjct: 93 LYLQRNSMRKLYTNSFLHLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHENKLDVFR 152
Query: 83 SDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFE 134
+D+FLGL SL+ L N I+ I++G F +L L++L L+DN I + N F+
Sbjct: 153 NDTFLGLESLEYLQADYNVIKRIESGAFRNLSKLRVLILNDNLIPMLPTNLFK 205
Score = 56.4 bits (130), Expect = 1e-06
Identities = 50/174 (28%), Positives = 81/174 (46%), Gaps = 10/174 (5%)
Query: 31 EEIDSEAFTST-----KKLFHVDLSNNYLYTLPEKL-FANNTFLETIDISNNRVVYVPSD 84
EEID F + LFH+ + + + F + F + ++ R +Y ++
Sbjct: 49 EEIDEPCFDPCYCEVKESLFHIHCDSKGFTNISQITEFWSRPFKLYLQRNSMRKLY--TN 106
Query: 85 SFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXX 143
SFL L + ++L N +Q+IQ G F+ LK L+ L L +NK++ ++ F
Sbjct: 107 SFLHLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHENKLDVFRNDTFLGLESLEYLQ 166
Query: 144 XDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENAL 197
D N +K I + F NL L L L N+NL+ + L +LDL+ N L
Sbjct: 167 ADYNVIKRIESGAFRNLSKLRVLIL-NDNLIPMLPTNLFKAVSLTHLDLRGNRL 219
Score = 56.0 bits (129), Expect = 1e-06
Identities = 46/172 (26%), Positives = 79/172 (45%), Gaps = 8/172 (4%)
Query: 2 FDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKL 61
F+N E LP + N K L L N +++I F + L + L NN + + +
Sbjct: 408 FNNISELLPRPL-----NAKKLYLSSNLIQKIYRSDFWNFSSLDLLHLGNNRISYVQDGA 462
Query: 62 FANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSL-KNLQILKL 120
F N L+++ ++ N + + F GL SL L N I+ IQ FSL NL++L L
Sbjct: 463 FINLPNLKSLFLNGNDIEKLTPGMFRGLQSLHYLYFEFNVIREIQPAAFSLMPNLKLLFL 522
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQ-LFNNLKCLIFLDLSNN 171
++N + + +AF +N +P + +L ++ +DL+ N
Sbjct: 523 NNNLLRTLPTDAFAGTSLARLNLR-KNYFLYLPVAGVLEHLNAIVQIDLNEN 573
Score = 52.0 bits (119), Expect = 2e-05
Identities = 57/228 (25%), Positives = 86/228 (37%), Gaps = 26/228 (11%)
Query: 114 NLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNL 173
N + L LS N I I + F N N++ + F NL L L L+ N++
Sbjct: 420 NAKKLYLSSNLIQKIYRSDFWNFSSLDLLHLGNNRISYVQDGAFINLPNLKSLFLNGNDI 479
Query: 174 MSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXX 233
L F L+ L L + N + +I FS NL+ L L+ N LR + AF G
Sbjct: 480 EKLTPGMFRGLQSLHYLYFEFNVIREIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAGT- 538
Query: 234 XXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLP-SRTLDYMPKLTIVKLSGNP 292
+L L L N F LP + L+++ + + L+ NP
Sbjct: 539 ------------------------SLARLNLRKNYFLYLPVAGVLEHLNAIVQIDLNENP 574
Query: 293 WHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGHFLKKLKFPELC 340
W C C + W+ C SP L ++ ++ LC
Sbjct: 575 WDCTCDLVPFKQWIETISSVSVVGDVLCRSPENLTHRDVRTIELEVLC 622
>U21128-1|AAA91639.1| 338|Homo sapiens lumican protein.
Length = 338
Score = 75.8 bits (178), Expect = 2e-12
Identities = 67/233 (28%), Positives = 114/233 (48%), Gaps = 19/233 (8%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLE--EIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+N ++++ FE++ +L+ L L N LE +I F+ K+L + +++N L E
Sbjct: 75 NNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHN---NLTES 131
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI-QNIQNGTFS-LKNLQIL 118
+ LE + +++N++ + SF GL +L + L N++ ++ + F LK+L+ L
Sbjct: 132 VGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYL 189
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
LS N+I + D NK+ NIP + F L +L LS+N L +G
Sbjct: 190 DLSFNQIARLPSGL---PVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELAD-SG 245
Query: 179 VEFESLKL--LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
+ S + L LDL N L IP T ++ NLE L N+L +I +F
Sbjct: 246 IPGNSFNVSSLVELDLSYNKLKNIP--TVNE--NLENYYLEVNQLEKFDIKSF 294
Score = 55.2 bits (127), Expect = 2e-06
Identities = 47/179 (26%), Positives = 81/179 (45%), Gaps = 9/179 (5%)
Query: 115 LQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLIFLDLSNNN 172
++ L L +N+I++I + AFEN D N L+N I ++F+ LK L L +++NN
Sbjct: 68 IKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNN 127
Query: 173 LMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGX 232
L G K L +L L N ++++ +F NL + L N+L+ ++A +
Sbjct: 128 LTESVG---PLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAF-- 180
Query: 233 XXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
++ + +L TLYLD N ++P L ++LS N
Sbjct: 181 KGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHN 239
Score = 54.4 bits (125), Expect = 4e-06
Identities = 55/178 (30%), Positives = 83/178 (46%), Gaps = 14/178 (7%)
Query: 49 LSNNYLYTLPEKLFANNTFLETIDISNNRV--VYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
L NN + + EK F N T L+ + + +N + + F L L+ L ++ N N+
Sbjct: 73 LRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHN---NLT 129
Query: 107 NGTFSL-KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLK-NIPTQLFNNLKCLI 164
L K+L+ L+L+ NKI + +FE N+LK + + F LK L
Sbjct: 130 ESVGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLE 187
Query: 165 FLDLSNNNLMSL-AGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
+LDLS N + L +G+ L L L N +S IPD F L+ L LS N+L
Sbjct: 188 YLDLSFNQIARLPSGLPVSLLTLY----LDNNKISNIPDEYFKRFNALQYLRLSHNEL 241
>U18728-1|AAA85268.1| 338|Homo sapiens lumican protein.
Length = 338
Score = 75.8 bits (178), Expect = 2e-12
Identities = 67/233 (28%), Positives = 114/233 (48%), Gaps = 19/233 (8%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLE--EIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+N ++++ FE++ +L+ L L N LE +I F+ K+L + +++N L E
Sbjct: 75 NNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHN---NLTES 131
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI-QNIQNGTFS-LKNLQIL 118
+ LE + +++N++ + SF GL +L + L N++ ++ + F LK+L+ L
Sbjct: 132 VGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYL 189
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
LS N+I + D NK+ NIP + F L +L LS+N L +G
Sbjct: 190 DLSFNQIARLPSGL---PVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELAD-SG 245
Query: 179 VEFESLKL--LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
+ S + L LDL N L IP T ++ NLE L N+L +I +F
Sbjct: 246 IPGNSFNVSSLVELDLSYNKLKNIP--TVNE--NLENYYLEVNQLEKFDIKSF 294
Score = 55.2 bits (127), Expect = 2e-06
Identities = 47/179 (26%), Positives = 81/179 (45%), Gaps = 9/179 (5%)
Query: 115 LQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLIFLDLSNNN 172
++ L L +N+I++I + AFEN D N L+N I ++F+ LK L L +++NN
Sbjct: 68 IKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNN 127
Query: 173 LMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGX 232
L G K L +L L N ++++ +F NL + L N+L+ ++A +
Sbjct: 128 LTESVG---PLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAF-- 180
Query: 233 XXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
++ + +L TLYLD N ++P L ++LS N
Sbjct: 181 KGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHN 239
Score = 54.0 bits (124), Expect = 6e-06
Identities = 55/178 (30%), Positives = 83/178 (46%), Gaps = 14/178 (7%)
Query: 49 LSNNYLYTLPEKLFANNTFLETIDISNNRV--VYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
L NN + + EK F N T L+ + + +N + + F L L+ L ++ N N+
Sbjct: 73 LRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHN---NLT 129
Query: 107 NGTFSL-KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLK-NIPTQLFNNLKCLI 164
L K+L+ L+L+ NKI + +FE N+LK + + F LK L
Sbjct: 130 ESVGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLE 187
Query: 165 FLDLSNNNLMSL-AGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
+LDLS N + L +G+ L L L N +S IPD F L+ L LS N+L
Sbjct: 188 YLDLSFNQIARLPSGLPVSLLTLY----LDNNKISNIPDEYFKRFNALQYLRLSHNEL 241
>BT006707-1|AAP35353.1| 338|Homo sapiens lumican protein.
Length = 338
Score = 75.8 bits (178), Expect = 2e-12
Identities = 67/233 (28%), Positives = 114/233 (48%), Gaps = 19/233 (8%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLE--EIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+N ++++ FE++ +L+ L L N LE +I F+ K+L + +++N L E
Sbjct: 75 NNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHN---NLTES 131
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI-QNIQNGTFS-LKNLQIL 118
+ LE + +++N++ + SF GL +L + L N++ ++ + F LK+L+ L
Sbjct: 132 VGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYL 189
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
LS N+I + D NK+ NIP + F L +L LS+N L +G
Sbjct: 190 DLSFNQIARLPSGL---PVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELAD-SG 245
Query: 179 VEFESLKL--LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
+ S + L LDL N L IP T ++ NLE L N+L +I +F
Sbjct: 246 IPGNSFNVSSLVELDLSYNKLKNIP--TVNE--NLENYYLEVNQLEKFDIKSF 294
Score = 55.2 bits (127), Expect = 2e-06
Identities = 47/179 (26%), Positives = 81/179 (45%), Gaps = 9/179 (5%)
Query: 115 LQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLIFLDLSNNN 172
++ L L +N+I++I + AFEN D N L+N I ++F+ LK L L +++NN
Sbjct: 68 IKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNN 127
Query: 173 LMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGX 232
L G K L +L L N ++++ +F NL + L N+L+ ++A +
Sbjct: 128 LTESVG---PLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAF-- 180
Query: 233 XXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
++ + +L TLYLD N ++P L ++LS N
Sbjct: 181 KGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHN 239
Score = 54.4 bits (125), Expect = 4e-06
Identities = 55/178 (30%), Positives = 83/178 (46%), Gaps = 14/178 (7%)
Query: 49 LSNNYLYTLPEKLFANNTFLETIDISNNRV--VYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
L NN + + EK F N T L+ + + +N + + F L L+ L ++ N N+
Sbjct: 73 LRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHN---NLT 129
Query: 107 NGTFSL-KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLK-NIPTQLFNNLKCLI 164
L K+L+ L+L+ NKI + +FE N+LK + + F LK L
Sbjct: 130 ESVGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLE 187
Query: 165 FLDLSNNNLMSL-AGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
+LDLS N + L +G+ L L L N +S IPD F L+ L LS N+L
Sbjct: 188 YLDLSFNQIARLPSGLPVSLLTLY----LDNNKISNIPDEYFKRFNALQYLRLSHNEL 241
>BC035997-1|AAH35997.1| 338|Homo sapiens lumican protein.
Length = 338
Score = 75.8 bits (178), Expect = 2e-12
Identities = 67/233 (28%), Positives = 114/233 (48%), Gaps = 19/233 (8%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLE--EIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+N ++++ FE++ +L+ L L N LE +I F+ K+L + +++N L E
Sbjct: 75 NNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHN---NLTES 131
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI-QNIQNGTFS-LKNLQIL 118
+ LE + +++N++ + SF GL +L + L N++ ++ + F LK+L+ L
Sbjct: 132 VGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYL 189
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
LS N+I + D NK+ NIP + F L +L LS+N L +G
Sbjct: 190 DLSFNQIARLPSGL---PVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELAD-SG 245
Query: 179 VEFESLKL--LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
+ S + L LDL N L IP T ++ NLE L N+L +I +F
Sbjct: 246 IPGNSFNVSSLVELDLSYNKLKNIP--TVNE--NLENYYLEVNQLEKFDIKSF 294
Score = 55.2 bits (127), Expect = 2e-06
Identities = 47/179 (26%), Positives = 81/179 (45%), Gaps = 9/179 (5%)
Query: 115 LQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLIFLDLSNNN 172
++ L L +N+I++I + AFEN D N L+N I ++F+ LK L L +++NN
Sbjct: 68 IKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNN 127
Query: 173 LMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGX 232
L G K L +L L N ++++ +F NL + L N+L+ ++A +
Sbjct: 128 LTESVG---PLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAF-- 180
Query: 233 XXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
++ + +L TLYLD N ++P L ++LS N
Sbjct: 181 KGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHN 239
Score = 54.4 bits (125), Expect = 4e-06
Identities = 55/178 (30%), Positives = 83/178 (46%), Gaps = 14/178 (7%)
Query: 49 LSNNYLYTLPEKLFANNTFLETIDISNNRV--VYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
L NN + + EK F N T L+ + + +N + + F L L+ L ++ N N+
Sbjct: 73 LRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHN---NLT 129
Query: 107 NGTFSL-KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLK-NIPTQLFNNLKCLI 164
L K+L+ L+L+ NKI + +FE N+LK + + F LK L
Sbjct: 130 ESVGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLE 187
Query: 165 FLDLSNNNLMSL-AGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
+LDLS N + L +G+ L L L N +S IPD F L+ L LS N+L
Sbjct: 188 YLDLSFNQIARLPSGLPVSLLTLY----LDNNKISNIPDEYFKRFNALQYLRLSHNEL 241
>BC007038-1|AAH07038.1| 338|Homo sapiens lumican protein.
Length = 338
Score = 75.8 bits (178), Expect = 2e-12
Identities = 67/233 (28%), Positives = 114/233 (48%), Gaps = 19/233 (8%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLE--EIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+N ++++ FE++ +L+ L L N LE +I F+ K+L + +++N L E
Sbjct: 75 NNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHN---NLTES 131
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI-QNIQNGTFS-LKNLQIL 118
+ LE + +++N++ + SF GL +L + L N++ ++ + F LK+L+ L
Sbjct: 132 VGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYL 189
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
LS N+I + D NK+ NIP + F L +L LS+N L +G
Sbjct: 190 DLSFNQIARLPSGL---PVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELAD-SG 245
Query: 179 VEFESLKL--LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
+ S + L LDL N L IP T ++ NLE L N+L +I +F
Sbjct: 246 IPGNSFNVSSLVELDLSYNKLKNIP--TVNE--NLENYYLEVNQLEKFDIKSF 294
Score = 55.2 bits (127), Expect = 2e-06
Identities = 47/179 (26%), Positives = 81/179 (45%), Gaps = 9/179 (5%)
Query: 115 LQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLIFLDLSNNN 172
++ L L +N+I++I + AFEN D N L+N I ++F+ LK L L +++NN
Sbjct: 68 IKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNN 127
Query: 173 LMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGX 232
L G K L +L L N ++++ +F NL + L N+L+ ++A +
Sbjct: 128 LTESVG---PLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAF-- 180
Query: 233 XXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
++ + +L TLYLD N ++P L ++LS N
Sbjct: 181 KGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHN 239
Score = 54.4 bits (125), Expect = 4e-06
Identities = 55/178 (30%), Positives = 83/178 (46%), Gaps = 14/178 (7%)
Query: 49 LSNNYLYTLPEKLFANNTFLETIDISNNRV--VYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
L NN + + EK F N T L+ + + +N + + F L L+ L ++ N N+
Sbjct: 73 LRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHN---NLT 129
Query: 107 NGTFSL-KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLK-NIPTQLFNNLKCLI 164
L K+L+ L+L+ NKI + +FE N+LK + + F LK L
Sbjct: 130 ESVGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLE 187
Query: 165 FLDLSNNNLMSL-AGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
+LDLS N + L +G+ L L L N +S IPD F L+ L LS N+L
Sbjct: 188 YLDLSFNQIARLPSGLPVSLLTLY----LDNNKISNIPDEYFKRFNALQYLRLSHNEL 241
>AY358115-1|AAQ88482.1| 593|Homo sapiens DAAT9248 protein.
Length = 593
Score = 75.8 bits (178), Expect = 2e-12
Identities = 89/354 (25%), Positives = 139/354 (39%), Gaps = 32/354 (9%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
+E +PGG+ ++ + L L N L + + L +DLS N L TL F
Sbjct: 51 LEAVPGGL---PLDTELLDLSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGL 107
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNK 124
L T+ + NR+ + F GL +L +LDL N+I +G F L +LQ L++ DN
Sbjct: 108 QSLLTLRLQGNRLRIMGPGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNH 167
Query: 125 INNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSL-AGV---- 179
+ ++ AF +R L +P L L+ L L ++ L AG
Sbjct: 168 LVFVAPGAFAGLAKLSTLTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGL 227
Query: 180 -EFESLKL------------------LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
+ + L++ L +L + LS +P L LDLS+N
Sbjct: 228 GQLKELEIHLWPSLEALDPGSLVGLNLSSLAITRCNLSSVPFQALYHLSFLRVLDLSQNP 287
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ I + AF L L + N +L
Sbjct: 288 ISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSP 347
Query: 281 PKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYS-PTCVSPWYLEGHFLKK 333
KL ++LSGNP CDC L++ +RL + S P C P +++G LK+
Sbjct: 348 DKLVTLRLSGNPLTCDCRLLWL---LRLRRHLDFGMSPPACAGPHHVQGKSLKE 398
Score = 75.8 bits (178), Expect = 2e-12
Identities = 76/275 (27%), Positives = 111/275 (40%), Gaps = 21/275 (7%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L G F L +L TLRLQ N L + F+ L +DL N + + F
Sbjct: 94 NQLSTLEPGAFHGLQSLLTLRLQGNRLRIMGPGVFSGLSALTLLDLRLNQIVLFLDGAFG 153
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L+ +++ +N +V+V +F GL L L L + + + + L L L+L +
Sbjct: 154 ELGSLQKLEVGDNHLVFVAPGAFAGLAKLSTLTLERCNLSTVPGLALARLPALVALRLRE 213
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA----- 177
I + A +LK + L+ +L+ L L NL SLA
Sbjct: 214 LDIGRLPAGALRGL----------GQLKELEIHLWPSLEALDPGSLVGLNLSSLAITRCN 263
Query: 178 --GVEFES---LKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGX 232
V F++ L LR LDL +N +S IP S L++L LS L I AF+G
Sbjct: 264 LSSVPFQALYHLSFLRVLDLSQNPISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGL 323
Query: 233 XXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGN 267
+ AF L TL L GN
Sbjct: 324 TAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGN 358
Score = 46.4 bits (105), Expect = 0.001
Identities = 48/198 (24%), Positives = 79/198 (39%), Gaps = 3/198 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DNH+ ++ G F L L TL L+R L + A L + L + LP
Sbjct: 165 DNHLVFVAPGAFAGLAKLSTLTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGAL 224
Query: 63 ANNTFLETIDISN-NRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ-NGTFSLKNLQILKL 120
L+ ++I + + S +GL +L L +++ + ++ + L L++L L
Sbjct: 225 RGLGQLKELEIHLWPSLEALDPGSLVGL-NLSSLAITRCNLSSVPFQALYHLSFLRVLDL 283
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
S N I+ I L +I F+ L LD+++N L +L
Sbjct: 284 SQNPISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETA 343
Query: 181 FESLKLLRNLDLKENALS 198
F S L L L N L+
Sbjct: 344 FPSPDKLVTLRLSGNPLT 361
>AL589765-16|CAI17178.1| 593|Homo sapiens leucine rich repeat
neuronal 6D protein.
Length = 593
Score = 75.8 bits (178), Expect = 2e-12
Identities = 89/354 (25%), Positives = 139/354 (39%), Gaps = 32/354 (9%)
Query: 6 VEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANN 65
+E +PGG+ ++ + L L N L + + L +DLS N L TL F
Sbjct: 51 LEAVPGGL---PLDTELLDLSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGL 107
Query: 66 TFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNK 124
L T+ + NR+ + F GL +L +LDL N+I +G F L +LQ L++ DN
Sbjct: 108 QSLLTLRLQGNRLRIMGPGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNH 167
Query: 125 INNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSL-AGV---- 179
+ ++ AF +R L +P L L+ L L ++ L AG
Sbjct: 168 LVFVAPGAFAGLAKLSTLTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGL 227
Query: 180 -EFESLKL------------------LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNK 220
+ + L++ L +L + LS +P L LDLS+N
Sbjct: 228 GQLKELEIHLWPSLEALDPGSLVGLNLSSLAITRCNLSSVPFQALYHLSFLRVLDLSQNP 287
Query: 221 LRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYM 280
+ I + AF L L + N +L
Sbjct: 288 ISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSP 347
Query: 281 PKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYS-PTCVSPWYLEGHFLKK 333
KL ++LSGNP CDC L++ +RL + S P C P +++G LK+
Sbjct: 348 DKLVTLRLSGNPLTCDCRLLWL---LRLRRHLDFGMSPPACAGPHHVQGKSLKE 398
Score = 75.8 bits (178), Expect = 2e-12
Identities = 76/275 (27%), Positives = 111/275 (40%), Gaps = 21/275 (7%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N + L G F L +L TLRLQ N L + F+ L +DL N + + F
Sbjct: 94 NQLSTLEPGAFHGLQSLLTLRLQGNRLRIMGPGVFSGLSALTLLDLRLNQIVLFLDGAFG 153
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSD 122
L+ +++ +N +V+V +F GL L L L + + + + L L L+L +
Sbjct: 154 ELGSLQKLEVGDNHLVFVAPGAFAGLAKLSTLTLERCNLSTVPGLALARLPALVALRLRE 213
Query: 123 NKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA----- 177
I + A +LK + L+ +L+ L L NL SLA
Sbjct: 214 LDIGRLPAGALRGL----------GQLKELEIHLWPSLEALDPGSLVGLNLSSLAITRCN 263
Query: 178 --GVEFES---LKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGX 232
V F++ L LR LDL +N +S IP S L++L LS L I AF+G
Sbjct: 264 LSSVPFQALYHLSFLRVLDLSQNPISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGL 323
Query: 233 XXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGN 267
+ AF L TL L GN
Sbjct: 324 TAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGN 358
Score = 46.4 bits (105), Expect = 0.001
Identities = 48/198 (24%), Positives = 79/198 (39%), Gaps = 3/198 (1%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
DNH+ ++ G F L L TL L+R L + A L + L + LP
Sbjct: 165 DNHLVFVAPGAFAGLAKLSTLTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGAL 224
Query: 63 ANNTFLETIDISN-NRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ-NGTFSLKNLQILKL 120
L+ ++I + + S +GL +L L +++ + ++ + L L++L L
Sbjct: 225 RGLGQLKELEIHLWPSLEALDPGSLVGL-NLSSLAITRCNLSSVPFQALYHLSFLRVLDL 283
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
S N I+ I L +I F+ L LD+++N L +L
Sbjct: 284 SQNPISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETA 343
Query: 181 FESLKLLRNLDLKENALS 198
F S L L L N L+
Sbjct: 344 FPSPDKLVTLRLSGNPLT 361
>AK223177-1|BAD96897.1| 338|Homo sapiens lumican variant protein.
Length = 338
Score = 75.8 bits (178), Expect = 2e-12
Identities = 67/233 (28%), Positives = 114/233 (48%), Gaps = 19/233 (8%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLE--EIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+N ++++ FE++ +L+ L L N LE +I F+ K+L + +++N L E
Sbjct: 75 NNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHN---NLTES 131
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI-QNIQNGTFS-LKNLQIL 118
+ LE + +++N++ + SF GL +L + L N++ ++ + F LK+L+ L
Sbjct: 132 VGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYL 189
Query: 119 KLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAG 178
LS N+I + D NK+ NIP + F L +L LS+N L +G
Sbjct: 190 DLSFNQIARLPSGP---PVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELAD-SG 245
Query: 179 VEFESLKL--LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
+ S + L LDL N L IP T ++ NLE L N+L +I +F
Sbjct: 246 IPGNSFNVSSLVELDLSYNKLKNIP--TVNE--NLENYYLEVNQLEKFDIKSF 294
Score = 54.0 bits (124), Expect = 6e-06
Identities = 55/177 (31%), Positives = 81/177 (45%), Gaps = 12/177 (6%)
Query: 49 LSNNYLYTLPEKLFANNTFLETIDISNNRV--VYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
L NN + + EK F N T L+ + + +N + + F L L+ L ++ N N+
Sbjct: 73 LRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHN---NLT 129
Query: 107 NGTFSL-KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLK-NIPTQLFNNLKCLI 164
L K+L+ L+L+ NKI + +FE N+LK + + F LK L
Sbjct: 130 ESVGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLE 187
Query: 165 FLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
+LDLS N + L S L L L N +S IPD F L+ L LS N+L
Sbjct: 188 YLDLSFNQIARLPSGPPVS---LLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNEL 241
Score = 53.6 bits (123), Expect = 7e-06
Identities = 47/179 (26%), Positives = 80/179 (44%), Gaps = 9/179 (5%)
Query: 115 LQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLIFLDLSNNN 172
++ L L +N+I++I + AFEN D N L+N I ++F+ LK L L +++NN
Sbjct: 68 IKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNN 127
Query: 173 LMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGX 232
L G K L +L L N ++++ +F NL + L N+L+ ++A +
Sbjct: 128 LTESVG---PLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAF-- 180
Query: 233 XXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
++ +L TLYLD N ++P L ++LS N
Sbjct: 181 KGLKSLEYLDLSFNQIARLPSGPPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHN 239
>BC020870-1|AAH20870.1| 649|Homo sapiens fibronectin leucine rich
transmembrane protein 3 protein.
Length = 649
Score = 75.4 bits (177), Expect = 2e-12
Identities = 62/245 (25%), Positives = 103/245 (42%), Gaps = 10/245 (4%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS--DNAFENXXXXXXXXXDRNKLKN 151
L L +N I+ I + S + L+ L L DN ++ +S + AF + RN L
Sbjct: 109 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLST 168
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ--IPDNTFSDCF 209
IP L ++ L L +N + +++ + L L+ L L N L+ + D F +
Sbjct: 169 IPWGLPRTIE---ELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 225
Query: 210 NLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
NL +L L +N L + V AFS L+ L L + N
Sbjct: 226 NLTELSLVRNSLTAAPVNL--PGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 283
Query: 270 PSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGH 329
+LP D + +T + L NPW+C C ++ W++ +K+ C +P + G
Sbjct: 284 SNLPQGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQAPEKVRGM 343
Query: 330 FLKKL 334
+K L
Sbjct: 344 AIKDL 348
Score = 48.0 bits (109), Expect = 4e-04
Identities = 36/124 (29%), Positives = 55/124 (44%), Gaps = 5/124 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEE--IDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
DN + + + L +LK L L N L + + F + L + L N L P
Sbjct: 184 DNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVN 243
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILK 119
L N L + + +N + VP ++F L L LD+S N + N+ G F L N+ L
Sbjct: 244 LPGTN--LRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLI 301
Query: 120 LSDN 123
L +N
Sbjct: 302 LRNN 305
>BC016048-1|AAH16048.1| 317|Homo sapiens LRRC38 protein protein.
Length = 317
Score = 75.4 bits (177), Expect = 2e-12
Identities = 41/124 (33%), Positives = 58/124 (46%)
Query: 190 LDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVH 249
LD + N+L + + TFS L LDLS N L + AF VH
Sbjct: 108 LDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLTQLGAGAFRSAGRLVKLSLANNNLVGVH 167
Query: 250 FKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLN 309
AF L++L L L+ N SL L +P L ++L GNPW CDC ++ +W++ N
Sbjct: 168 EDAFETLESLQVLELNDNNLRSLSVAALAALPALRSLRLDGNPWLCDCDFAHLFSWIQEN 227
Query: 310 EMKI 313
K+
Sbjct: 228 ASKL 231
Score = 56.8 bits (131), Expect = 8e-07
Identities = 36/121 (29%), Positives = 62/121 (51%), Gaps = 1/121 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ +P F +L L + N L ++ F+ + KL +DLS N L L F
Sbjct: 89 NRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLTQLGAGAFR 148
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ L + ++NN +V V D+F L SLQ+L+L+ N ++++ +L L+ L+L
Sbjct: 149 SAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLSVAALAALPALRSLRLDG 208
Query: 123 N 123
N
Sbjct: 209 N 209
Score = 54.4 bits (125), Expect = 4e-06
Identities = 30/113 (26%), Positives = 61/113 (53%), Gaps = 1/113 (0%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNR 77
++++ L + N ++ I + F L ++D NN L +L E F+ + L +D+S N
Sbjct: 79 LDVRKLLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNN 138
Query: 78 VVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNIS 129
+ + + +F L L L+ N + + F +L++LQ+L+L+DN + ++S
Sbjct: 139 LTQLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLS 191
Score = 53.6 bits (123), Expect = 7e-06
Identities = 33/111 (29%), Positives = 53/111 (47%)
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
L ++ N+I I ++ F N L+++ F+ L+FLDLS NNL L
Sbjct: 84 LLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLTQLG 143
Query: 178 GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITA 228
F S L L L N L + ++ F +L+ L+L+ N LR +++ A
Sbjct: 144 AGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLSVAA 194
Score = 43.2 bits (97), Expect = 0.010
Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 1/102 (0%)
Query: 100 NKIQNIQNGTFSLK-NLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFN 158
N+IQ I F +L L +N + ++ + F N L + F
Sbjct: 89 NRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLTQLGAGAFR 148
Query: 159 NLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQI 200
+ L+ L L+NNNL+ + FE+L+ L+ L+L +N L +
Sbjct: 149 SAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSL 190
Score = 39.5 bits (88), Expect = 0.13
Identities = 26/98 (26%), Positives = 46/98 (46%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + L G F L L L N L ++ + AF S +L + L+NN L + E F
Sbjct: 112 NNSLRSLEEGTFSGSAKLVFLDLSYNNLTQLGAGAFRSAGRLVKLSLANNNLVGVHEDAF 171
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKN 100
L+ +++++N + + + L +L+ L L N
Sbjct: 172 ETLESLQVLELNDNNLRSLSVAALAALPALRSLRLDGN 209
>AY358319-1|AAQ88685.1| 649|Homo sapiens FLRT3 protein.
Length = 649
Score = 75.4 bits (177), Expect = 2e-12
Identities = 62/245 (25%), Positives = 103/245 (42%), Gaps = 10/245 (4%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS--DNAFENXXXXXXXXXDRNKLKN 151
L L +N I+ I + S + L+ L L DN ++ +S + AF + RN L
Sbjct: 109 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLST 168
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ--IPDNTFSDCF 209
IP L ++ L L +N + +++ + L L+ L L N L+ + D F +
Sbjct: 169 IPWGLPRTIE---ELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 225
Query: 210 NLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
NL +L L +N L + V AFS L+ L L + N
Sbjct: 226 NLTELSLVRNSLTAAPVNL--PGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 283
Query: 270 PSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGH 329
+LP D + +T + L NPW+C C ++ W++ +K+ C +P + G
Sbjct: 284 SNLPQGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQAPEKVRGM 343
Query: 330 FLKKL 334
+K L
Sbjct: 344 AIKDL 348
Score = 48.0 bits (109), Expect = 4e-04
Identities = 36/124 (29%), Positives = 55/124 (44%), Gaps = 5/124 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEE--IDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
DN + + + L +LK L L N L + + F + L + L N L P
Sbjct: 184 DNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVN 243
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILK 119
L N L + + +N + VP ++F L L LD+S N + N+ G F L N+ L
Sbjct: 244 LPGTN--LRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLI 301
Query: 120 LSDN 123
L +N
Sbjct: 302 LRNN 305
>AL603749-2|CAH70436.1| 294|Homo sapiens leucine rich repeat
containing 38 protein.
Length = 294
Score = 75.4 bits (177), Expect = 2e-12
Identities = 41/124 (33%), Positives = 58/124 (46%)
Query: 190 LDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVH 249
LD + N+L + + TFS L LDLS N L + AF VH
Sbjct: 85 LDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLTQLGAGAFRSAGRLVKLSLANNNLVGVH 144
Query: 250 FKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLN 309
AF L++L L L+ N SL L +P L ++L GNPW CDC ++ +W++ N
Sbjct: 145 EDAFETLESLQVLELNDNNLRSLSVAALAALPALRSLRLDGNPWLCDCDFAHLFSWIQEN 204
Query: 310 EMKI 313
K+
Sbjct: 205 ASKL 208
Score = 56.8 bits (131), Expect = 8e-07
Identities = 36/121 (29%), Positives = 62/121 (51%), Gaps = 1/121 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ +P F +L L + N L ++ F+ + KL +DLS N L L F
Sbjct: 66 NRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLTQLGAGAFR 125
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ L + ++NN +V V D+F L SLQ+L+L+ N ++++ +L L+ L+L
Sbjct: 126 SAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLSVAALAALPALRSLRLDG 185
Query: 123 N 123
N
Sbjct: 186 N 186
Score = 54.4 bits (125), Expect = 4e-06
Identities = 30/113 (26%), Positives = 61/113 (53%), Gaps = 1/113 (0%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNR 77
++++ L + N ++ I + F L ++D NN L +L E F+ + L +D+S N
Sbjct: 56 LDVRKLLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNN 115
Query: 78 VVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNIS 129
+ + + +F L L L+ N + + F +L++LQ+L+L+DN + ++S
Sbjct: 116 LTQLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLS 168
Score = 53.6 bits (123), Expect = 7e-06
Identities = 33/111 (29%), Positives = 53/111 (47%)
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
L ++ N+I I ++ F N L+++ F+ L+FLDLS NNL L
Sbjct: 61 LLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLTQLG 120
Query: 178 GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITA 228
F S L L L N L + ++ F +L+ L+L+ N LR +++ A
Sbjct: 121 AGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLSVAA 171
Score = 44.4 bits (100), Expect = 0.004
Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 4/132 (3%)
Query: 70 TIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLK-NLQILKLSDNKINNI 128
T+D + + VP L + L + + N+IQ I F +L L +N + ++
Sbjct: 39 TVDCRDRGLPSVPDPFPLDVRKLLV---AGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSL 95
Query: 129 SDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLR 188
+ F N L + F + L+ L L+NNNL+ + FE+L+ L+
Sbjct: 96 EEGTFSGSAKLVFLDLSYNNLTQLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQ 155
Query: 189 NLDLKENALSQI 200
L+L +N L +
Sbjct: 156 VLELNDNNLRSL 167
Score = 39.5 bits (88), Expect = 0.13
Identities = 26/98 (26%), Positives = 46/98 (46%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + L G F L L L N L ++ + AF S +L + L+NN L + E F
Sbjct: 89 NNSLRSLEEGTFSGSAKLVFLDLSYNNLTQLGAGAFRSAGRLVKLSLANNNLVGVHEDAF 148
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKN 100
L+ +++++N + + + L +L+ L L N
Sbjct: 149 ETLESLQVLELNDNNLRSLSVAALAALPALRSLRLDGN 186
>AL354712-1|CAI21926.1| 294|Homo sapiens leucine rich repeat
containing 38 protein.
Length = 294
Score = 75.4 bits (177), Expect = 2e-12
Identities = 41/124 (33%), Positives = 58/124 (46%)
Query: 190 LDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVH 249
LD + N+L + + TFS L LDLS N L + AF VH
Sbjct: 85 LDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLTQLGAGAFRSAGRLVKLSLANNNLVGVH 144
Query: 250 FKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLN 309
AF L++L L L+ N SL L +P L ++L GNPW CDC ++ +W++ N
Sbjct: 145 EDAFETLESLQVLELNDNNLRSLSVAALAALPALRSLRLDGNPWLCDCDFAHLFSWIQEN 204
Query: 310 EMKI 313
K+
Sbjct: 205 ASKL 208
Score = 56.8 bits (131), Expect = 8e-07
Identities = 36/121 (29%), Positives = 62/121 (51%), Gaps = 1/121 (0%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ +P F +L L + N L ++ F+ + KL +DLS N L L F
Sbjct: 66 NRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLTQLGAGAFR 125
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSD 122
+ L + ++NN +V V D+F L SLQ+L+L+ N ++++ +L L+ L+L
Sbjct: 126 SAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLSVAALAALPALRSLRLDG 185
Query: 123 N 123
N
Sbjct: 186 N 186
Score = 54.4 bits (125), Expect = 4e-06
Identities = 30/113 (26%), Positives = 61/113 (53%), Gaps = 1/113 (0%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNR 77
++++ L + N ++ I + F L ++D NN L +L E F+ + L +D+S N
Sbjct: 56 LDVRKLLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNN 115
Query: 78 VVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNIS 129
+ + + +F L L L+ N + + F +L++LQ+L+L+DN + ++S
Sbjct: 116 LTQLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLS 168
Score = 53.6 bits (123), Expect = 7e-06
Identities = 33/111 (29%), Positives = 53/111 (47%)
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
L ++ N+I I ++ F N L+++ F+ L+FLDLS NNL L
Sbjct: 61 LLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLTQLG 120
Query: 178 GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITA 228
F S L L L N L + ++ F +L+ L+L+ N LR +++ A
Sbjct: 121 AGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLSVAA 171
Score = 44.4 bits (100), Expect = 0.004
Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 4/132 (3%)
Query: 70 TIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLK-NLQILKLSDNKINNI 128
T+D + + VP L + L + + N+IQ I F +L L +N + ++
Sbjct: 39 TVDCRDRGLPSVPDPFPLDVRKLLV---AGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSL 95
Query: 129 SDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLR 188
+ F N L + F + L+ L L+NNNL+ + FE+L+ L+
Sbjct: 96 EEGTFSGSAKLVFLDLSYNNLTQLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQ 155
Query: 189 NLDLKENALSQI 200
L+L +N L +
Sbjct: 156 VLELNDNNLRSL 167
Score = 39.5 bits (88), Expect = 0.13
Identities = 26/98 (26%), Positives = 46/98 (46%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + L G F L L L N L ++ + AF S +L + L+NN L + E F
Sbjct: 89 NNSLRSLEEGTFSGSAKLVFLDLSYNNLTQLGAGAFRSAGRLVKLSLANNNLVGVHEDAF 148
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKN 100
L+ +++++N + + + L +L+ L L N
Sbjct: 149 ETLESLQVLELNDNNLRSLSVAALAALPALRSLRLDGN 186
>AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 372
Score = 75.4 bits (177), Expect = 2e-12
Identities = 82/292 (28%), Positives = 128/292 (43%), Gaps = 11/292 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N ++ LP I +L +L L L+ N L I + L ++L NN + TLPE L
Sbjct: 60 ENKIKQLPAEI-GNLSSLSRLGLRYNRLSAIP-RSLAKCSALEELNLENNNISTLPESLL 117
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLS 121
++ L ++ ++ N P ++ L++ N+I I G FS K L L +
Sbjct: 118 SSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMK 177
Query: 122 DNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
DN++ ++ + F N+L IP + + L L L LSNN L L
Sbjct: 178 DNQLTSLPLD-FGTWTSMVELNLATNQLTKIPEDV-SGLVSLEVLILSNNLLKKLPH-GL 234
Query: 182 ESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXX 241
+L+ LR LDL+EN L +P N + +L+KL L+ N+L + G
Sbjct: 235 GNLRKLRELDLEENKLESLP-NEIAYLKDLQKLVLTNNQL--TTLPRGIGHLTNLTHLGL 291
Query: 242 XXXXYEVHFKAFSMLKNLTTLYLDGN-MFPSLPSRTLDYMPKLTIVKLSGNP 292
+ L+NL LYL+ N SLP L KL+I+ + P
Sbjct: 292 GENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFE-LALCSKLSIMSIENCP 342
Score = 64.1 bits (149), Expect = 5e-09
Identities = 51/201 (25%), Positives = 87/201 (43%), Gaps = 6/201 (2%)
Query: 89 LYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNK 148
L L++LDL NK++ I + + L +L L L N+I + + +N NK
Sbjct: 4 LKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTV-EKDIKNLSKLSMLSIRENK 62
Query: 149 LKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDC 208
+K +P ++ NL L L L N L ++ L L+L+ N +S +P++ S
Sbjct: 63 IKQLPAEI-GNLSSLSRLGLRYNRLSAIPR-SLAKCSALEELNLENNNISTLPESLLSSL 120
Query: 209 FNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNM 268
L L L++N + + ++ F FS K L+ L + N
Sbjct: 121 VKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQ 180
Query: 269 FPSLPSRTLDYMPKLTIVKLS 289
SLP LD+ ++V+L+
Sbjct: 181 LTSLP---LDFGTWTSMVELN 198
Score = 35.5 bits (78), Expect = 2.1
Identities = 32/134 (23%), Positives = 55/134 (41%), Gaps = 4/134 (2%)
Query: 158 NNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLS 217
+NLK L LDL +N L + V + L L L L+ N ++ + + + L L +
Sbjct: 2 DNLKKLRMLDLRHNKLREIPSVVYR-LDSLTTLYLRFNRITTV-EKDIKNLSKLSMLSIR 59
Query: 218 KNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTL 277
+NK++ + A G ++ + L L L+ N +LP L
Sbjct: 60 ENKIK--QLPAEIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLL 117
Query: 278 DYMPKLTIVKLSGN 291
+ KL + L+ N
Sbjct: 118 SSLVKLNSLTLARN 131
>AL132826-1|CAB86687.1| 649|Homo sapiens fibronectin leucine rich
transmembrane protein 3 protein.
Length = 649
Score = 75.4 bits (177), Expect = 2e-12
Identities = 62/245 (25%), Positives = 103/245 (42%), Gaps = 10/245 (4%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS--DNAFENXXXXXXXXXDRNKLKN 151
L L +N I+ I + S + L+ L L DN ++ +S + AF + RN L
Sbjct: 109 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLST 168
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ--IPDNTFSDCF 209
IP L ++ L L +N + +++ + L L+ L L N L+ + D F +
Sbjct: 169 IPWGLPRTIE---ELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 225
Query: 210 NLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
NL +L L +N L + V AFS L+ L L + N
Sbjct: 226 NLTELSLVRNSLTAAPVNL--PGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 283
Query: 270 PSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGH 329
+LP D + +T + L NPW+C C ++ W++ +K+ C +P + G
Sbjct: 284 SNLPQGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQAPEKVRGM 343
Query: 330 FLKKL 334
+K L
Sbjct: 344 AIKDL 348
Score = 48.0 bits (109), Expect = 4e-04
Identities = 36/124 (29%), Positives = 55/124 (44%), Gaps = 5/124 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEE--IDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
DN + + + L +LK L L N L + + F + L + L N L P
Sbjct: 184 DNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVN 243
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILK 119
L N L + + +N + VP ++F L L LD+S N + N+ G F L N+ L
Sbjct: 244 LPGTN--LRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLI 301
Query: 120 LSDN 123
L +N
Sbjct: 302 LRNN 305
>AK095610-1|BAC04589.1| 370|Homo sapiens protein ( Homo sapiens
cDNA FLJ38291 fis, clone FCBBF3009069, weakly similar to
Homo sapiens HT017 mRNA. ).
Length = 370
Score = 75.4 bits (177), Expect = 2e-12
Identities = 41/124 (33%), Positives = 66/124 (53%), Gaps = 1/124 (0%)
Query: 1 MFDNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
+ +N + LP F +L +L+ L L N+L+ + F L + L NN + TL
Sbjct: 75 LLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRD 134
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILK 119
L ++ L +D+S N + +P F GL +L+ L L N++QN+ TF L NLQ+L+
Sbjct: 135 LLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLANLQLLQ 194
Query: 120 LSDN 123
+ DN
Sbjct: 195 VGDN 198
Score = 65.3 bits (152), Expect = 2e-09
Identities = 38/139 (27%), Positives = 60/139 (43%)
Query: 168 LSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINIT 227
L NN L +L F +L L+ LDL N L ++P + F D NL +L L N +R ++
Sbjct: 75 LLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRD 134
Query: 228 AFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVK 287
++ F L L +L L N +L T + + L +++
Sbjct: 135 LLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLANLQLLQ 194
Query: 288 LSGNPWHCDCHALYISAWV 306
+ NPW CDC+ W+
Sbjct: 195 VGDNPWECDCNLREFKHWM 213
Score = 60.9 bits (141), Expect = 5e-08
Identities = 39/115 (33%), Positives = 57/115 (49%), Gaps = 1/115 (0%)
Query: 21 KTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNRVVY 80
+TL L N L + S AF + L +DLSNN+L LP +F + T L + + NN +
Sbjct: 71 RTLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRT 130
Query: 81 VPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFE 134
+ D L+ LDLS N + + G F L L+ L L N++ N+ FE
Sbjct: 131 LDRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFE 185
Score = 57.6 bits (133), Expect = 4e-07
Identities = 35/112 (31%), Positives = 52/112 (46%)
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
L L +NK++ + AF N N L +P +F +L L L L NN++ +L
Sbjct: 73 LLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTLD 132
Query: 178 GVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
LLR+LDL N L+Q+P F L L L N+L+ ++ F
Sbjct: 133 RDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTF 184
Score = 56.8 bits (131), Expect = 8e-07
Identities = 47/167 (28%), Positives = 75/167 (44%), Gaps = 5/167 (2%)
Query: 54 LYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-L 112
L T P ++ LE +D S + VP D +L +L+ NK+ + + F+ L
Sbjct: 36 LPTCPFSCKCDSRSLE-VDCSGLGLTTVPPDVPAATRTLLLLN---NKLSALPSWAFANL 91
Query: 113 KNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNN 172
+LQ L LS+N ++ + + F + N ++ + L + L LDLS N
Sbjct: 92 SSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRDLLRHSPLLRHLDLSING 151
Query: 173 LMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKN 219
L L F+ L LR+L L+ N L + TF NL+ L + N
Sbjct: 152 LAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLANLQLLQVGDN 198
>AK074909-1|BAC11284.1| 649|Homo sapiens protein ( Homo sapiens
cDNA FLJ90428 fis, clone NT2RP3000616, highly similar to
Leucine-rich repeat transmembrane protein FLRT3
precursor. ).
Length = 649
Score = 75.4 bits (177), Expect = 2e-12
Identities = 62/245 (25%), Positives = 103/245 (42%), Gaps = 10/245 (4%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS--DNAFENXXXXXXXXXDRNKLKN 151
L L +N I+ I + S + L+ L L DN ++ +S + AF + RN L
Sbjct: 109 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLST 168
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ--IPDNTFSDCF 209
IP L ++ L L +N + +++ + L L+ L L N L+ + D F +
Sbjct: 169 IPWGLPRTIE---ELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 225
Query: 210 NLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
NL +L L +N L + V AFS L+ L L + N
Sbjct: 226 NLTELSLVRNSLTAAPVNL--PGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 283
Query: 270 PSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGH 329
+LP D + +T + L NPW+C C ++ W++ +K+ C +P + G
Sbjct: 284 SNLPQGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQAPEKVRGM 343
Query: 330 FLKKL 334
+K L
Sbjct: 344 AIKDL 348
Score = 48.0 bits (109), Expect = 4e-04
Identities = 36/124 (29%), Positives = 55/124 (44%), Gaps = 5/124 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEE--IDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
DN + + + L +LK L L N L + + F + L + L N L P
Sbjct: 184 DNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVN 243
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILK 119
L N L + + +N + VP ++F L L LD+S N + N+ G F L N+ L
Sbjct: 244 LPGTN--LRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLI 301
Query: 120 LSDN 123
L +N
Sbjct: 302 LRNN 305
>AK074883-1|BAC11265.1| 627|Homo sapiens protein ( Homo sapiens
cDNA FLJ90402 fis, clone NT2RP2006004, highly similar to
Leucine-rich repeat transmembrane protein FLRT3
precursor. ).
Length = 627
Score = 75.4 bits (177), Expect = 2e-12
Identities = 62/245 (25%), Positives = 103/245 (42%), Gaps = 10/245 (4%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS--DNAFENXXXXXXXXXDRNKLKN 151
L L +N I+ I + S + L+ L L DN ++ +S + AF + RN L
Sbjct: 109 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLST 168
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ--IPDNTFSDCF 209
IP L ++ L L +N + +++ + L L+ L L N L+ + D F +
Sbjct: 169 IPWGLPRTIE---ELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 225
Query: 210 NLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
NL +L L +N L + V AFS L+ L L + N
Sbjct: 226 NLTELSLVRNSLTAAPVNL--PGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 283
Query: 270 PSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGH 329
+LP D + +T + L NPW+C C ++ W++ +K+ C +P + G
Sbjct: 284 SNLPQGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQAPEKVRGM 343
Query: 330 FLKKL 334
+K L
Sbjct: 344 AIKDL 348
Score = 48.0 bits (109), Expect = 4e-04
Identities = 36/124 (29%), Positives = 55/124 (44%), Gaps = 5/124 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEE--IDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
DN + + + L +LK L L N L + + F + L + L N L P
Sbjct: 184 DNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVN 243
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILK 119
L N L + + +N + VP ++F L L LD+S N + N+ G F L N+ L
Sbjct: 244 LPGTN--LRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLI 301
Query: 120 LSDN 123
L +N
Sbjct: 302 LRNN 305
>AK027694-1|BAB55303.1| 623|Homo sapiens protein ( Homo sapiens
cDNA FLJ14788 fis, clone NT2RP4000925, weakly similar to
FIBROMODULIN PRECURSOR. ).
Length = 623
Score = 75.4 bits (177), Expect = 2e-12
Identities = 62/245 (25%), Positives = 103/245 (42%), Gaps = 10/245 (4%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS--DNAFENXXXXXXXXXDRNKLKN 151
L L +N I+ I + S + L+ L L DN ++ +S + AF + RN L
Sbjct: 83 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLST 142
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ--IPDNTFSDCF 209
IP L ++ L L +N + +++ + L L+ L L N L+ + D F +
Sbjct: 143 IPWGLPRTIE---ELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 199
Query: 210 NLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
NL +L L +N L + V AFS L+ L L + N
Sbjct: 200 NLTELSLVRNSLTAAPVNL--PGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 257
Query: 270 PSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGH 329
+LP D + +T + L NPW+C C ++ W++ +K+ C +P + G
Sbjct: 258 SNLPQGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQAPEKVRGM 317
Query: 330 FLKKL 334
+K L
Sbjct: 318 AIKDL 322
Score = 48.0 bits (109), Expect = 4e-04
Identities = 36/124 (29%), Positives = 55/124 (44%), Gaps = 5/124 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEE--IDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
DN + + + L +LK L L N L + + F + L + L N L P
Sbjct: 158 DNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVN 217
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILK 119
L N L + + +N + VP ++F L L LD+S N + N+ G F L N+ L
Sbjct: 218 LPGTN--LRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLI 275
Query: 120 LSDN 123
L +N
Sbjct: 276 LRNN 279
>AK027297-1|BAB55023.1| 649|Homo sapiens protein ( Homo sapiens
cDNA FLJ14391 fis, clone HEMBA1003077, weakly similar to
SLIT PROTEIN PRECURSOR. ).
Length = 649
Score = 75.4 bits (177), Expect = 2e-12
Identities = 62/245 (25%), Positives = 103/245 (42%), Gaps = 10/245 (4%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS--DNAFENXXXXXXXXXDRNKLKN 151
L L +N I+ I + S + L+ L L DN ++ +S + AF + RN L
Sbjct: 109 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLST 168
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ--IPDNTFSDCF 209
IP L ++ L L +N + +++ + L L+ L L N L+ + D F +
Sbjct: 169 IPWGLPRTIE---ELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 225
Query: 210 NLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
NL +L L +N L + V AFS L+ L L + N
Sbjct: 226 NLTELSLVRNSLTAAPVNL--PGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 283
Query: 270 PSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGH 329
+LP D + +T + L NPW+C C ++ W++ +K+ C +P + G
Sbjct: 284 SNLPQGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQAPEKVRGM 343
Query: 330 FLKKL 334
+K L
Sbjct: 344 AIKDL 348
Score = 48.0 bits (109), Expect = 4e-04
Identities = 36/124 (29%), Positives = 55/124 (44%), Gaps = 5/124 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEE--IDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
DN + + + L +LK L L N L + + F + L + L N L P
Sbjct: 184 DNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVN 243
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILK 119
L N L + + +N + VP ++F L L LD+S N + N+ G F L N+ L
Sbjct: 244 LPGTN--LRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLI 301
Query: 120 LSDN 123
L +N
Sbjct: 302 LRNN 305
>AF169677-1|AAF28461.1| 649|Homo sapiens leucine-rich repeat
transmembrane protein FLRT3 protein.
Length = 649
Score = 75.4 bits (177), Expect = 2e-12
Identities = 62/245 (25%), Positives = 103/245 (42%), Gaps = 10/245 (4%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS--DNAFENXXXXXXXXXDRNKLKN 151
L L +N I+ I + S + L+ L L DN ++ +S + AF + RN L
Sbjct: 109 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLST 168
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ--IPDNTFSDCF 209
IP L ++ L L +N + +++ + L L+ L L N L+ + D F +
Sbjct: 169 IPWGLPRTIE---ELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 225
Query: 210 NLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
NL +L L +N L + V AFS L+ L L + N
Sbjct: 226 NLTELSLVRNSLTAAPVNL--PGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 283
Query: 270 PSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGH 329
+LP D + +T + L NPW+C C ++ W++ +K+ C +P + G
Sbjct: 284 SNLPQGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQAPEKVRGM 343
Query: 330 FLKKL 334
+K L
Sbjct: 344 AIKDL 348
Score = 48.0 bits (109), Expect = 4e-04
Identities = 36/124 (29%), Positives = 55/124 (44%), Gaps = 5/124 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEE--IDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
DN + + + L +LK L L N L + + F + L + L N L P
Sbjct: 184 DNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVN 243
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILK 119
L N L + + +N + VP ++F L L LD+S N + N+ G F L N+ L
Sbjct: 244 LPGTN--LRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLI 301
Query: 120 LSDN 123
L +N
Sbjct: 302 LRNN 305
>AB040902-1|BAA95993.1| 662|Homo sapiens KIAA1469 protein protein.
Length = 662
Score = 75.4 bits (177), Expect = 2e-12
Identities = 62/245 (25%), Positives = 103/245 (42%), Gaps = 10/245 (4%)
Query: 95 LDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS--DNAFENXXXXXXXXXDRNKLKN 151
L L +N I+ I + S + L+ L L DN ++ +S + AF + RN L
Sbjct: 122 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLST 181
Query: 152 IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ--IPDNTFSDCF 209
IP L ++ L L +N + +++ + L L+ L L N L+ + D F +
Sbjct: 182 IPWGLPRTIE---ELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 238
Query: 210 NLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMF 269
NL +L L +N L + V AFS L+ L L + N
Sbjct: 239 NLTELSLVRNSLTAAPVNL--PGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 296
Query: 270 PSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWYLEGH 329
+LP D + +T + L NPW+C C ++ W++ +K+ C +P + G
Sbjct: 297 SNLPQGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQAPEKVRGM 356
Query: 330 FLKKL 334
+K L
Sbjct: 357 AIKDL 361
Score = 48.0 bits (109), Expect = 4e-04
Identities = 36/124 (29%), Positives = 55/124 (44%), Gaps = 5/124 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEE--IDSEAFTSTKKLFHVDLSNNYLYTLPEK 60
DN + + + L +LK L L N L + + F + L + L N L P
Sbjct: 197 DNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVN 256
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILK 119
L N L + + +N + VP ++F L L LD+S N + N+ G F L N+ L
Sbjct: 257 LPGTN--LRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLI 314
Query: 120 LSDN 123
L +N
Sbjct: 315 LRNN 318
>M14219-1|AAB00774.1| 359|Homo sapiens proteoglycan core protein
protein.
Length = 359
Score = 74.9 bits (176), Expect = 3e-12
Identities = 56/202 (27%), Positives = 91/202 (45%), Gaps = 9/202 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + + G F++L NL L L N + ++ AFT KL + LS N L LPEK+
Sbjct: 90 NNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKM- 148
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKN--KIQNIQNGTF-SLKNLQILK 119
L+ + N + V +F GL + +++L N K I+NG F +K L ++
Sbjct: 149 --PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
++D I +I D NK+ + L L L LS N++ ++
Sbjct: 207 IADTNITSIPQGL---PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 263
Query: 180 EFESLKLLRNLDLKENALSQIP 201
+ LR L L N L+++P
Sbjct: 264 SLANTPHLRELHLDNNKLTRVP 285
Score = 56.8 bits (131), Expect = 8e-07
Identities = 56/223 (25%), Positives = 95/223 (42%), Gaps = 30/223 (13%)
Query: 94 ILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNI 152
+LDL NKI I++G F +LKNL L L +NKI+ +S AF +N+LK +
Sbjct: 85 LLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL 144
Query: 153 PTQL---------------------FNNLKCLIFLDLSNNNLMSLAGVE---FESLKLLR 188
P ++ FN L +I ++L N L S +G+E F+ +K L
Sbjct: 145 PEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKS-SGIENGAFQGMKKLS 203
Query: 189 NLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEV 248
+ + + ++ IP +L +L L NK+ ++ + G V
Sbjct: 204 YIRIADTNITSIPQGLPP---SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 260
Query: 249 HFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + +L L+LD N +P ++ + +V L N
Sbjct: 261 DNGSLANTPHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNN 302
Score = 55.6 bits (128), Expect = 2e-06
Identities = 47/181 (25%), Positives = 81/181 (44%), Gaps = 7/181 (3%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+DL NN + + + F N L + + NN++ V +F L L+ L LSKN+++ +
Sbjct: 86 LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELP 145
Query: 107 NGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLI 164
K LQ L+ +N+I + F N LK+ I F +K L
Sbjct: 146 EK--MPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLS 203
Query: 165 FLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
++ +++ N+ S+ S L L L N +S++ + NL KL LS N + +
Sbjct: 204 YIRIADTNITSIPQGLPPS---LTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 260
Query: 225 N 225
+
Sbjct: 261 D 261
Score = 47.2 bits (107), Expect = 6e-04
Identities = 43/166 (25%), Positives = 70/166 (42%), Gaps = 9/166 (5%)
Query: 20 LKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYT--LPEKLFANNTFLETIDISNNR 77
L+ LR N + ++ F ++ ++L N L + + F L I I++
Sbjct: 152 LQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTN 211
Query: 78 VVYVPSDSFLGLY-SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFEN 135
+ +P GL SL L L NKI + + L NL L LS N I+ + + + N
Sbjct: 212 ITSIPQ----GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLAN 267
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
D NKL +P L + K + + L NNN+ + +F
Sbjct: 268 TPHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNNNISVVGSSDF 312
>CR541946-1|CAG46744.1| 359|Homo sapiens DCN protein.
Length = 359
Score = 74.9 bits (176), Expect = 3e-12
Identities = 56/202 (27%), Positives = 91/202 (45%), Gaps = 9/202 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + + G F++L NL L L N + ++ AFT KL + LS N L LPEK+
Sbjct: 90 NNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKM- 148
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKN--KIQNIQNGTF-SLKNLQILK 119
L+ + N + V +F GL + +++L N K I+NG F +K L ++
Sbjct: 149 --PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
++D I +I D NK+ + L L L LS N++ ++
Sbjct: 207 IADTNITSIPQGL---PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 263
Query: 180 EFESLKLLRNLDLKENALSQIP 201
+ LR L L N L+++P
Sbjct: 264 SLANTPHLRELHLDNNKLTRVP 285
Score = 56.8 bits (131), Expect = 8e-07
Identities = 56/223 (25%), Positives = 95/223 (42%), Gaps = 30/223 (13%)
Query: 94 ILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNI 152
+LDL NKI I++G F +LKNL L L +NKI+ +S AF +N+LK +
Sbjct: 85 LLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL 144
Query: 153 PTQL---------------------FNNLKCLIFLDLSNNNLMSLAGVE---FESLKLLR 188
P ++ FN L +I ++L N L S +G+E F+ +K L
Sbjct: 145 PEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKS-SGIENGAFQGMKKLS 203
Query: 189 NLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEV 248
+ + + ++ IP +L +L L NK+ ++ + G V
Sbjct: 204 YIRIADTNITSIPQGLPP---SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 260
Query: 249 HFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + +L L+LD N +P ++ + +V L N
Sbjct: 261 DNGSLANTPHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNN 302
Score = 55.6 bits (128), Expect = 2e-06
Identities = 47/181 (25%), Positives = 81/181 (44%), Gaps = 7/181 (3%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+DL NN + + + F N L + + NN++ V +F L L+ L LSKN+++ +
Sbjct: 86 LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELP 145
Query: 107 NGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLI 164
K LQ L+ +N+I + F N LK+ I F +K L
Sbjct: 146 EK--MPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLS 203
Query: 165 FLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
++ +++ N+ S+ S L L L N +S++ + NL KL LS N + +
Sbjct: 204 YIRIADTNITSIPQGLPPS---LTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 260
Query: 225 N 225
+
Sbjct: 261 D 261
Score = 47.2 bits (107), Expect = 6e-04
Identities = 43/166 (25%), Positives = 70/166 (42%), Gaps = 9/166 (5%)
Query: 20 LKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYT--LPEKLFANNTFLETIDISNNR 77
L+ LR N + ++ F ++ ++L N L + + F L I I++
Sbjct: 152 LQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTN 211
Query: 78 VVYVPSDSFLGLY-SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFEN 135
+ +P GL SL L L NKI + + L NL L LS N I+ + + + N
Sbjct: 212 ITSIPQ----GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLAN 267
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
D NKL +P L + K + + L NNN+ + +F
Sbjct: 268 TPHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNNNISVVGSSDF 312
>CR407676-1|CAG28604.1| 359|Homo sapiens DCN protein.
Length = 359
Score = 74.9 bits (176), Expect = 3e-12
Identities = 56/202 (27%), Positives = 91/202 (45%), Gaps = 9/202 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + + G F++L NL L L N + ++ AFT KL + LS N L LPEK+
Sbjct: 90 NNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKM- 148
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKN--KIQNIQNGTF-SLKNLQILK 119
L+ + N + V +F GL + +++L N K I+NG F +K L ++
Sbjct: 149 --PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
++D I +I D NK+ + L L L LS N++ ++
Sbjct: 207 IADTNITSIPQGL---PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 263
Query: 180 EFESLKLLRNLDLKENALSQIP 201
+ LR L L N L+++P
Sbjct: 264 SLANTPHLRELHLDNNKLTRVP 285
Score = 56.8 bits (131), Expect = 8e-07
Identities = 56/223 (25%), Positives = 95/223 (42%), Gaps = 30/223 (13%)
Query: 94 ILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNI 152
+LDL NKI I++G F +LKNL L L +NKI+ +S AF +N+LK +
Sbjct: 85 LLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL 144
Query: 153 PTQL---------------------FNNLKCLIFLDLSNNNLMSLAGVE---FESLKLLR 188
P ++ FN L +I ++L N L S +G+E F+ +K L
Sbjct: 145 PEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKS-SGIENGAFQGMKKLS 203
Query: 189 NLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEV 248
+ + + ++ IP +L +L L NK+ ++ + G V
Sbjct: 204 YIRIADTNITSIPQGLPP---SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 260
Query: 249 HFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + +L L+LD N +P ++ + +V L N
Sbjct: 261 DNGSLANTPHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNN 302
Score = 55.6 bits (128), Expect = 2e-06
Identities = 47/181 (25%), Positives = 81/181 (44%), Gaps = 7/181 (3%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+DL NN + + + F N L + + NN++ V +F L L+ L LSKN+++ +
Sbjct: 86 LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELP 145
Query: 107 NGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLI 164
K LQ L+ +N+I + F N LK+ I F +K L
Sbjct: 146 EK--MPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLS 203
Query: 165 FLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
++ +++ N+ S+ S L L L N +S++ + NL KL LS N + +
Sbjct: 204 YIRIADTNITSIPQGLPPS---LTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 260
Query: 225 N 225
+
Sbjct: 261 D 261
Score = 47.2 bits (107), Expect = 6e-04
Identities = 43/166 (25%), Positives = 70/166 (42%), Gaps = 9/166 (5%)
Query: 20 LKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYT--LPEKLFANNTFLETIDISNNR 77
L+ LR N + ++ F ++ ++L N L + + F L I I++
Sbjct: 152 LQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTN 211
Query: 78 VVYVPSDSFLGLY-SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFEN 135
+ +P GL SL L L NKI + + L NL L LS N I+ + + + N
Sbjct: 212 ITSIPQ----GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLAN 267
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
D NKL +P L + K + + L NNN+ + +F
Sbjct: 268 TPHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNNNISVVGSSDF 312
>BT019800-1|AAV38603.1| 359|Homo sapiens decorin protein.
Length = 359
Score = 74.9 bits (176), Expect = 3e-12
Identities = 56/202 (27%), Positives = 91/202 (45%), Gaps = 9/202 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + + G F++L NL L L N + ++ AFT KL + LS N L LPEK+
Sbjct: 90 NNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKM- 148
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKN--KIQNIQNGTF-SLKNLQILK 119
L+ + N + V +F GL + +++L N K I+NG F +K L ++
Sbjct: 149 --PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
++D I +I D NK+ + L L L LS N++ ++
Sbjct: 207 IADTNITSIPQGL---PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 263
Query: 180 EFESLKLLRNLDLKENALSQIP 201
+ LR L L N L+++P
Sbjct: 264 SLANTPHLRELHLDNNKLTRVP 285
Score = 56.8 bits (131), Expect = 8e-07
Identities = 56/223 (25%), Positives = 95/223 (42%), Gaps = 30/223 (13%)
Query: 94 ILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNI 152
+LDL NKI I++G F +LKNL L L +NKI+ +S AF +N+LK +
Sbjct: 85 LLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL 144
Query: 153 PTQL---------------------FNNLKCLIFLDLSNNNLMSLAGVE---FESLKLLR 188
P ++ FN L +I ++L N L S +G+E F+ +K L
Sbjct: 145 PEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKS-SGIENGAFQGMKKLS 203
Query: 189 NLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEV 248
+ + + ++ IP +L +L L NK+ ++ + G V
Sbjct: 204 YIRIADTNITSIPQGLPP---SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 260
Query: 249 HFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + +L L+LD N +P ++ + +V L N
Sbjct: 261 DNGSLANTPHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNN 302
Score = 55.6 bits (128), Expect = 2e-06
Identities = 47/181 (25%), Positives = 81/181 (44%), Gaps = 7/181 (3%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+DL NN + + + F N L + + NN++ V +F L L+ L LSKN+++ +
Sbjct: 86 LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELP 145
Query: 107 NGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLI 164
K LQ L+ +N+I + F N LK+ I F +K L
Sbjct: 146 EK--MPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLS 203
Query: 165 FLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
++ +++ N+ S+ S L L L N +S++ + NL KL LS N + +
Sbjct: 204 YIRIADTNITSIPQGLPPS---LTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 260
Query: 225 N 225
+
Sbjct: 261 D 261
Score = 47.2 bits (107), Expect = 6e-04
Identities = 43/166 (25%), Positives = 70/166 (42%), Gaps = 9/166 (5%)
Query: 20 LKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYT--LPEKLFANNTFLETIDISNNR 77
L+ LR N + ++ F ++ ++L N L + + F L I I++
Sbjct: 152 LQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTN 211
Query: 78 VVYVPSDSFLGLY-SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFEN 135
+ +P GL SL L L NKI + + L NL L LS N I+ + + + N
Sbjct: 212 ITSIPQ----GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLAN 267
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
D NKL +P L + K + + L NNN+ + +F
Sbjct: 268 TPHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNNNISVVGSSDF 312
>BC130290-1|AAI30291.1| 660|Homo sapiens fibronectin leucine rich
transmembrane protein 2 protein.
Length = 660
Score = 74.9 bits (176), Expect = 3e-12
Identities = 64/222 (28%), Positives = 105/222 (47%), Gaps = 8/222 (3%)
Query: 12 GIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETI 71
G L N++++ Y ++D K + + L N + T+ A LE +
Sbjct: 79 GFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEEL 138
Query: 72 DISNNRV--VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNIS 129
+ +N + V V +F SL++L LSKN + ++ G +LQ L++ +N+I IS
Sbjct: 139 HLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGL--PVDLQELRVDENRIAVIS 196
Query: 130 DNAFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
D AF+N D N L N I F++L L + N+L S + L+
Sbjct: 197 DMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSL-SHPPPDLPGTHLI 255
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
R L L++N ++ IP FS+ LE+LD+S N+LR + F
Sbjct: 256 R-LYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVF 296
Score = 70.9 bits (166), Expect = 4e-11
Identities = 57/249 (22%), Positives = 101/249 (40%), Gaps = 10/249 (4%)
Query: 91 SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS--DNAFENXXXXXXXXXDRN 147
++++L L +N IQ I + L L+ L L DN I+ + D AF +N
Sbjct: 110 NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKN 169
Query: 148 KLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ--IPDNTF 205
L ++P L +L+ L + N + ++ + F++L L L + N L+ I + TF
Sbjct: 170 HLSSVPVGLPVDLQ---ELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTF 226
Query: 206 SDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLD 265
S L++ + +N L + + AFS L+ L L +
Sbjct: 227 SHLTKLKEFSIVRNSLS--HPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDIS 284
Query: 266 GNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWY 325
N L D + L + NPW CDC +++ W++ + C P
Sbjct: 285 NNQLRMLTQGVFDNLSNLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQ 344
Query: 326 LEGHFLKKL 334
+ G +++L
Sbjct: 345 VRGMAVREL 353
Score = 62.9 bits (146), Expect = 1e-08
Identities = 54/198 (27%), Positives = 93/198 (46%), Gaps = 10/198 (5%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSE--AFTSTKKLFHVDLSNNYLYTLPEK 60
+N+++ + L+ L+ L L N + + E AF L + LS N+L ++P
Sbjct: 118 ENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVG 177
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQN--IQNGTFS-LKNLQI 117
L + L+ + + NR+ + +F L SL+ L + N + N I GTFS L L+
Sbjct: 178 LPVD---LQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKE 234
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
+ N +++ + D N++ +IP F+NL+ L LD+SNN L L
Sbjct: 235 FSIVRNSLSHPPPD-LPGTHLIRLYLQD-NQINHIPLTAFSNLRKLERLDISNNQLRMLT 292
Query: 178 GVEFESLKLLRNLDLKEN 195
F++L L+ L + N
Sbjct: 293 QGVFDNLSNLKQLTARNN 310
Score = 62.1 bits (144), Expect = 2e-08
Identities = 56/207 (27%), Positives = 93/207 (44%), Gaps = 12/207 (5%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTL--PEKLFANNTFLETIDISNN 76
N++ L LQ N ++ I A KL + L +N + T+ + F L+ + +S N
Sbjct: 110 NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKN 169
Query: 77 RVVYVPSDSFLGL-YSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINN--ISDNA 132
+ VP +GL LQ L + +N+I I + F +L +L+ L + N + N I++
Sbjct: 170 HLSSVP----VGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGT 225
Query: 133 FENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDL 192
F + RN L + P L LI L L +N + + F +L+ L LD+
Sbjct: 226 FSHLTKLKEFSIVRNSLSHPPPDLPGTH--LIRLYLQDNQINHIPLTAFSNLRKLERLDI 283
Query: 193 KENALSQIPDNTFSDCFNLEKLDLSKN 219
N L + F + NL++L N
Sbjct: 284 SNNQLRMLTQGVFDNLSNLKQLTARNN 310
>BC126249-1|AAI26250.1| 660|Homo sapiens fibronectin leucine rich
transmembrane protein 2 protein.
Length = 660
Score = 74.9 bits (176), Expect = 3e-12
Identities = 64/222 (28%), Positives = 105/222 (47%), Gaps = 8/222 (3%)
Query: 12 GIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETI 71
G L N++++ Y ++D K + + L N + T+ A LE +
Sbjct: 79 GFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEEL 138
Query: 72 DISNNRV--VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNIS 129
+ +N + V V +F SL++L LSKN + ++ G +LQ L++ +N+I IS
Sbjct: 139 HLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGL--PVDLQELRVDENRIAVIS 196
Query: 130 DNAFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
D AF+N D N L N I F++L L + N+L S + L+
Sbjct: 197 DMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSL-SHPPPDLPGTHLI 255
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
R L L++N ++ IP FS+ LE+LD+S N+LR + F
Sbjct: 256 R-LYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVF 296
Score = 70.9 bits (166), Expect = 4e-11
Identities = 57/249 (22%), Positives = 101/249 (40%), Gaps = 10/249 (4%)
Query: 91 SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS--DNAFENXXXXXXXXXDRN 147
++++L L +N IQ I + L L+ L L DN I+ + D AF +N
Sbjct: 110 NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKN 169
Query: 148 KLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ--IPDNTF 205
L ++P L +L+ L + N + ++ + F++L L L + N L+ I + TF
Sbjct: 170 HLSSVPVGLPVDLQ---ELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTF 226
Query: 206 SDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLD 265
S L++ + +N L + + AFS L+ L L +
Sbjct: 227 SHLTKLKEFSIVRNSLS--HPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDIS 284
Query: 266 GNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWY 325
N L D + L + NPW CDC +++ W++ + C P
Sbjct: 285 NNQLRMLTQGVFDNLSNLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQ 344
Query: 326 LEGHFLKKL 334
+ G +++L
Sbjct: 345 VRGMAVREL 353
Score = 62.9 bits (146), Expect = 1e-08
Identities = 54/198 (27%), Positives = 93/198 (46%), Gaps = 10/198 (5%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSE--AFTSTKKLFHVDLSNNYLYTLPEK 60
+N+++ + L+ L+ L L N + + E AF L + LS N+L ++P
Sbjct: 118 ENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVG 177
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQN--IQNGTFS-LKNLQI 117
L + L+ + + NR+ + +F L SL+ L + N + N I GTFS L L+
Sbjct: 178 LPVD---LQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKE 234
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
+ N +++ + D N++ +IP F+NL+ L LD+SNN L L
Sbjct: 235 FSIVRNSLSHPPPD-LPGTHLIRLYLQD-NQINHIPLTAFSNLRKLERLDISNNQLRMLT 292
Query: 178 GVEFESLKLLRNLDLKEN 195
F++L L+ L + N
Sbjct: 293 QGVFDNLSNLKQLTARNN 310
Score = 62.1 bits (144), Expect = 2e-08
Identities = 56/207 (27%), Positives = 93/207 (44%), Gaps = 12/207 (5%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTL--PEKLFANNTFLETIDISNN 76
N++ L LQ N ++ I A KL + L +N + T+ + F L+ + +S N
Sbjct: 110 NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKN 169
Query: 77 RVVYVPSDSFLGL-YSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINN--ISDNA 132
+ VP +GL LQ L + +N+I I + F +L +L+ L + N + N I++
Sbjct: 170 HLSSVP----VGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGT 225
Query: 133 FENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDL 192
F + RN L + P L LI L L +N + + F +L+ L LD+
Sbjct: 226 FSHLTKLKEFSIVRNSLSHPPPDLPGTH--LIRLYLQDNQINHIPLTAFSNLRKLERLDI 283
Query: 193 KENALSQIPDNTFSDCFNLEKLDLSKN 219
N L + F + NL++L N
Sbjct: 284 SNNQLRMLTQGVFDNLSNLKQLTARNN 310
>BC005322-1|AAH05322.1| 359|Homo sapiens decorin protein.
Length = 359
Score = 74.9 bits (176), Expect = 3e-12
Identities = 56/202 (27%), Positives = 91/202 (45%), Gaps = 9/202 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + + G F++L NL L L N + ++ AFT KL + LS N L LPEK+
Sbjct: 90 NNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKM- 148
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKN--KIQNIQNGTF-SLKNLQILK 119
L+ + N + V +F GL + +++L N K I+NG F +K L ++
Sbjct: 149 --PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
++D I +I D NK+ + L L L LS N++ ++
Sbjct: 207 IADTNITSIPQGL---PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 263
Query: 180 EFESLKLLRNLDLKENALSQIP 201
+ LR L L N L+++P
Sbjct: 264 SLANTPHLRELHLDNNKLTRVP 285
Score = 56.8 bits (131), Expect = 8e-07
Identities = 56/223 (25%), Positives = 95/223 (42%), Gaps = 30/223 (13%)
Query: 94 ILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNI 152
+LDL NKI I++G F +LKNL L L +NKI+ +S AF +N+LK +
Sbjct: 85 LLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL 144
Query: 153 PTQL---------------------FNNLKCLIFLDLSNNNLMSLAGVE---FESLKLLR 188
P ++ FN L +I ++L N L S +G+E F+ +K L
Sbjct: 145 PEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKS-SGIENGAFQGMKKLS 203
Query: 189 NLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEV 248
+ + + ++ IP +L +L L NK+ ++ + G V
Sbjct: 204 YIRIADTNITSIPQGLPP---SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 260
Query: 249 HFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + +L L+LD N +P ++ + +V L N
Sbjct: 261 DNGSLANTPHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNN 302
Score = 55.6 bits (128), Expect = 2e-06
Identities = 47/181 (25%), Positives = 81/181 (44%), Gaps = 7/181 (3%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+DL NN + + + F N L + + NN++ V +F L L+ L LSKN+++ +
Sbjct: 86 LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELP 145
Query: 107 NGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLI 164
K LQ L+ +N+I + F N LK+ I F +K L
Sbjct: 146 EK--MPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLS 203
Query: 165 FLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
++ +++ N+ S+ S L L L N +S++ + NL KL LS N + +
Sbjct: 204 YIRIADTNITSIPQGLPPS---LTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 260
Query: 225 N 225
+
Sbjct: 261 D 261
Score = 47.2 bits (107), Expect = 6e-04
Identities = 43/166 (25%), Positives = 70/166 (42%), Gaps = 9/166 (5%)
Query: 20 LKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYT--LPEKLFANNTFLETIDISNNR 77
L+ LR N + ++ F ++ ++L N L + + F L I I++
Sbjct: 152 LQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTN 211
Query: 78 VVYVPSDSFLGLY-SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFEN 135
+ +P GL SL L L NKI + + L NL L LS N I+ + + + N
Sbjct: 212 ITSIPQ----GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLAN 267
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
D NKL +P L + K + + L NNN+ + +F
Sbjct: 268 TPHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNNNISVVGSSDF 312
>AY358287-1|AAQ88654.1| 660|Homo sapiens FLRT2 protein.
Length = 660
Score = 74.9 bits (176), Expect = 3e-12
Identities = 64/222 (28%), Positives = 105/222 (47%), Gaps = 8/222 (3%)
Query: 12 GIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETI 71
G L N++++ Y ++D K + + L N + T+ A LE +
Sbjct: 79 GFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEEL 138
Query: 72 DISNNRV--VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNIS 129
+ +N + V V +F SL++L LSKN + ++ G +LQ L++ +N+I IS
Sbjct: 139 HLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGL--PVDLQELRVDENRIAVIS 196
Query: 130 DNAFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
D AF+N D N L N I F++L L + N+L S + L+
Sbjct: 197 DMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSL-SHPPPDLPGTHLI 255
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
R L L++N ++ IP FS+ LE+LD+S N+LR + F
Sbjct: 256 R-LYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVF 296
Score = 70.9 bits (166), Expect = 4e-11
Identities = 57/249 (22%), Positives = 101/249 (40%), Gaps = 10/249 (4%)
Query: 91 SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS--DNAFENXXXXXXXXXDRN 147
++++L L +N IQ I + L L+ L L DN I+ + D AF +N
Sbjct: 110 NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKN 169
Query: 148 KLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ--IPDNTF 205
L ++P L +L+ L + N + ++ + F++L L L + N L+ I + TF
Sbjct: 170 HLSSVPVGLPVDLQ---ELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTF 226
Query: 206 SDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLD 265
S L++ + +N L + + AFS L+ L L +
Sbjct: 227 SHLTKLKEFSIVRNSLS--HPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDIS 284
Query: 266 GNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWY 325
N L D + L + NPW CDC +++ W++ + C P
Sbjct: 285 NNQLRMLTQGVFDNLSNLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQ 344
Query: 326 LEGHFLKKL 334
+ G +++L
Sbjct: 345 VRGMAVREL 353
Score = 62.9 bits (146), Expect = 1e-08
Identities = 54/198 (27%), Positives = 93/198 (46%), Gaps = 10/198 (5%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSE--AFTSTKKLFHVDLSNNYLYTLPEK 60
+N+++ + L+ L+ L L N + + E AF L + LS N+L ++P
Sbjct: 118 ENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVG 177
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQN--IQNGTFS-LKNLQI 117
L + L+ + + NR+ + +F L SL+ L + N + N I GTFS L L+
Sbjct: 178 LPVD---LQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKE 234
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
+ N +++ + D N++ +IP F+NL+ L LD+SNN L L
Sbjct: 235 FSIVRNSLSHPPPD-LPGTHLIRLYLQD-NQINHIPLTAFSNLRKLERLDISNNQLRMLT 292
Query: 178 GVEFESLKLLRNLDLKEN 195
F++L L+ L + N
Sbjct: 293 QGVFDNLSNLKQLTARNN 310
Score = 62.1 bits (144), Expect = 2e-08
Identities = 56/207 (27%), Positives = 93/207 (44%), Gaps = 12/207 (5%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTL--PEKLFANNTFLETIDISNN 76
N++ L LQ N ++ I A KL + L +N + T+ + F L+ + +S N
Sbjct: 110 NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKN 169
Query: 77 RVVYVPSDSFLGL-YSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINN--ISDNA 132
+ VP +GL LQ L + +N+I I + F +L +L+ L + N + N I++
Sbjct: 170 HLSSVP----VGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGT 225
Query: 133 FENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDL 192
F + RN L + P L LI L L +N + + F +L+ L LD+
Sbjct: 226 FSHLTKLKEFSIVRNSLSHPPPDLPGTH--LIRLYLQDNQINHIPLTAFSNLRKLERLDI 283
Query: 193 KENALSQIPDNTFSDCFNLEKLDLSKN 219
N L + F + NL++L N
Sbjct: 284 SNNQLRMLTQGVFDNLSNLKQLTARNN 310
>AF491944-1|AAL92176.1| 359|Homo sapiens decorin protein.
Length = 359
Score = 74.9 bits (176), Expect = 3e-12
Identities = 56/202 (27%), Positives = 91/202 (45%), Gaps = 9/202 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + + G F++L NL L L N + ++ AFT KL + LS N L LPEK+
Sbjct: 90 NNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKM- 148
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKN--KIQNIQNGTF-SLKNLQILK 119
L+ + N + V +F GL + +++L N K I+NG F +K L ++
Sbjct: 149 --PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
++D I +I D NK+ + L L L LS N++ ++
Sbjct: 207 IADTNITSIPQGL---PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 263
Query: 180 EFESLKLLRNLDLKENALSQIP 201
+ LR L L N L+++P
Sbjct: 264 SLANTPHLRELHLDNNKLTRVP 285
Score = 56.8 bits (131), Expect = 8e-07
Identities = 56/223 (25%), Positives = 95/223 (42%), Gaps = 30/223 (13%)
Query: 94 ILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNI 152
+LDL NKI I++G F +LKNL L L +NKI+ +S AF +N+LK +
Sbjct: 85 LLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL 144
Query: 153 PTQL---------------------FNNLKCLIFLDLSNNNLMSLAGVE---FESLKLLR 188
P ++ FN L +I ++L N L S +G+E F+ +K L
Sbjct: 145 PEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKS-SGIENGAFQGMKKLS 203
Query: 189 NLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEV 248
+ + + ++ IP +L +L L NK+ ++ + G V
Sbjct: 204 YIRIADTNITSIPQGLPP---SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 260
Query: 249 HFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + +L L+LD N +P ++ + +V L N
Sbjct: 261 DNGSLANTPHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNN 302
Score = 55.6 bits (128), Expect = 2e-06
Identities = 47/181 (25%), Positives = 81/181 (44%), Gaps = 7/181 (3%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+DL NN + + + F N L + + NN++ V +F L L+ L LSKN+++ +
Sbjct: 86 LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELP 145
Query: 107 NGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLI 164
K LQ L+ +N+I + F N LK+ I F +K L
Sbjct: 146 EK--MPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLS 203
Query: 165 FLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
++ +++ N+ S+ S L L L N +S++ + NL KL LS N + +
Sbjct: 204 YIRIADTNITSIPQGLPPS---LTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 260
Query: 225 N 225
+
Sbjct: 261 D 261
Score = 47.2 bits (107), Expect = 6e-04
Identities = 43/166 (25%), Positives = 70/166 (42%), Gaps = 9/166 (5%)
Query: 20 LKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYT--LPEKLFANNTFLETIDISNNR 77
L+ LR N + ++ F ++ ++L N L + + F L I I++
Sbjct: 152 LQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTN 211
Query: 78 VVYVPSDSFLGLY-SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFEN 135
+ +P GL SL L L NKI + + L NL L LS N I+ + + + N
Sbjct: 212 ITSIPQ----GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLAN 267
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
D NKL +P L + K + + L NNN+ + +F
Sbjct: 268 TPHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNNNISVVGSSDF 312
>AF169676-1|AAF28460.1| 660|Homo sapiens leucine-rich repeat
transmembrane protein FLRT2 protein.
Length = 660
Score = 74.9 bits (176), Expect = 3e-12
Identities = 64/222 (28%), Positives = 105/222 (47%), Gaps = 8/222 (3%)
Query: 12 GIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETI 71
G L N++++ Y ++D K + + L N + T+ A LE +
Sbjct: 79 GFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEEL 138
Query: 72 DISNNRV--VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNIS 129
+ +N + V V +F SL++L LSKN + ++ G +LQ L++ +N+I IS
Sbjct: 139 HLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGL--PVDLQELRVDENRIAVIS 196
Query: 130 DNAFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
D AF+N D N L N I F++L L + N+L S + L+
Sbjct: 197 DMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSL-SHPPPDLPGTHLI 255
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
R L L++N ++ IP FS+ LE+LD+S N+LR + F
Sbjct: 256 R-LYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVF 296
Score = 70.9 bits (166), Expect = 4e-11
Identities = 57/249 (22%), Positives = 101/249 (40%), Gaps = 10/249 (4%)
Query: 91 SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS--DNAFENXXXXXXXXXDRN 147
++++L L +N IQ I + L L+ L L DN I+ + D AF +N
Sbjct: 110 NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKN 169
Query: 148 KLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ--IPDNTF 205
L ++P L +L+ L + N + ++ + F++L L L + N L+ I + TF
Sbjct: 170 HLSSVPVGLPVDLQ---ELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTF 226
Query: 206 SDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLD 265
S L++ + +N L + + AFS L+ L L +
Sbjct: 227 SHLTKLKEFSIVRNSLS--HPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDIS 284
Query: 266 GNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWY 325
N L D + L + NPW CDC +++ W++ + C P
Sbjct: 285 NNQLRMLTQGVFDNLSNLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQ 344
Query: 326 LEGHFLKKL 334
+ G +++L
Sbjct: 345 VRGMAVREL 353
Score = 62.9 bits (146), Expect = 1e-08
Identities = 54/198 (27%), Positives = 93/198 (46%), Gaps = 10/198 (5%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSE--AFTSTKKLFHVDLSNNYLYTLPEK 60
+N+++ + L+ L+ L L N + + E AF L + LS N+L ++P
Sbjct: 118 ENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVG 177
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQN--IQNGTFS-LKNLQI 117
L + L+ + + NR+ + +F L SL+ L + N + N I GTFS L L+
Sbjct: 178 LPVD---LQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKE 234
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
+ N +++ + D N++ +IP F+NL+ L LD+SNN L L
Sbjct: 235 FSIVRNSLSHPPPD-LPGTHLIRLYLQD-NQINHIPLTAFSNLRKLERLDISNNQLRMLT 292
Query: 178 GVEFESLKLLRNLDLKEN 195
F++L L+ L + N
Sbjct: 293 QGVFDNLSNLKQLTARNN 310
Score = 62.1 bits (144), Expect = 2e-08
Identities = 56/207 (27%), Positives = 93/207 (44%), Gaps = 12/207 (5%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTL--PEKLFANNTFLETIDISNN 76
N++ L LQ N ++ I A KL + L +N + T+ + F L+ + +S N
Sbjct: 110 NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKN 169
Query: 77 RVVYVPSDSFLGL-YSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINN--ISDNA 132
+ VP +GL LQ L + +N+I I + F +L +L+ L + N + N I++
Sbjct: 170 HLSSVP----VGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGT 225
Query: 133 FENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDL 192
F + RN L + P L LI L L +N + + F +L+ L LD+
Sbjct: 226 FSHLTKLKEFSIVRNSLSHPPPDLPGTH--LIRLYLQDNQINHIPLTAFSNLRKLERLDI 283
Query: 193 KENALSQIPDNTFSDCFNLEKLDLSKN 219
N L + F + NL++L N
Sbjct: 284 SNNQLRMLTQGVFDNLSNLKQLTARNN 310
>AF138300-1|AAD44713.1| 359|Homo sapiens decorin variant A protein.
Length = 359
Score = 74.9 bits (176), Expect = 3e-12
Identities = 56/202 (27%), Positives = 91/202 (45%), Gaps = 9/202 (4%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + + G F++L NL L L N + ++ AFT KL + LS N L LPEK+
Sbjct: 90 NNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKM- 148
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKN--KIQNIQNGTF-SLKNLQILK 119
L+ + N + V +F GL + +++L N K I+NG F +K L ++
Sbjct: 149 --PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 120 LSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGV 179
++D I +I D NK+ + L L L LS N++ ++
Sbjct: 207 IADTNITSIPQGL---PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 263
Query: 180 EFESLKLLRNLDLKENALSQIP 201
+ LR L L N L+++P
Sbjct: 264 SLANTPHLRELHLDNNKLTRVP 285
Score = 56.8 bits (131), Expect = 8e-07
Identities = 56/223 (25%), Positives = 95/223 (42%), Gaps = 30/223 (13%)
Query: 94 ILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNI 152
+LDL NKI I++G F +LKNL L L +NKI+ +S AF +N+LK +
Sbjct: 85 LLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL 144
Query: 153 PTQL---------------------FNNLKCLIFLDLSNNNLMSLAGVE---FESLKLLR 188
P ++ FN L +I ++L N L S +G+E F+ +K L
Sbjct: 145 PEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKS-SGIENGAFQGMKKLS 203
Query: 189 NLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEV 248
+ + + ++ IP +L +L L NK+ ++ + G V
Sbjct: 204 YIRIADTNITSIPQGLPP---SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 260
Query: 249 HFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTIVKLSGN 291
+ + +L L+LD N +P ++ + +V L N
Sbjct: 261 DNGSLANTPHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNN 302
Score = 55.6 bits (128), Expect = 2e-06
Identities = 47/181 (25%), Positives = 81/181 (44%), Gaps = 7/181 (3%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
+DL NN + + + F N L + + NN++ V +F L L+ L LSKN+++ +
Sbjct: 86 LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELP 145
Query: 107 NGTFSLKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLI 164
K LQ L+ +N+I + F N LK+ I F +K L
Sbjct: 146 EK--MPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLS 203
Query: 165 FLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFI 224
++ +++ N+ S+ S L L L N +S++ + NL KL LS N + +
Sbjct: 204 YIRIADTNITSIPQGLPPS---LTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 260
Query: 225 N 225
+
Sbjct: 261 D 261
Score = 47.2 bits (107), Expect = 6e-04
Identities = 43/166 (25%), Positives = 70/166 (42%), Gaps = 9/166 (5%)
Query: 20 LKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYT--LPEKLFANNTFLETIDISNNR 77
L+ LR N + ++ F ++ ++L N L + + F L I I++
Sbjct: 152 LQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTN 211
Query: 78 VVYVPSDSFLGLY-SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNISDNAFEN 135
+ +P GL SL L L NKI + + L NL L LS N I+ + + + N
Sbjct: 212 ITSIPQ----GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLAN 267
Query: 136 XXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEF 181
D NKL +P L + K + + L NNN+ + +F
Sbjct: 268 TPHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNNNISVVGSSDF 312
>AB007865-1|BAA23701.2| 706|Homo sapiens KIAA0405 protein.
Length = 706
Score = 74.9 bits (176), Expect = 3e-12
Identities = 64/222 (28%), Positives = 105/222 (47%), Gaps = 8/222 (3%)
Query: 12 GIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETI 71
G L N++++ Y ++D K + + L N + T+ A LE +
Sbjct: 125 GFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEEL 184
Query: 72 DISNNRV--VYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFSLKNLQILKLSDNKINNIS 129
+ +N + V V +F SL++L LSKN + ++ G +LQ L++ +N+I IS
Sbjct: 185 HLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGL--PVDLQELRVDENRIAVIS 242
Query: 130 DNAFENXXXXXXXXXDRNKLKN--IPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLL 187
D AF+N D N L N I F++L L + N+L S + L+
Sbjct: 243 DMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSL-SHPPPDLPGTHLI 301
Query: 188 RNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
R L L++N ++ IP FS+ LE+LD+S N+LR + F
Sbjct: 302 R-LYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVF 342
Score = 70.9 bits (166), Expect = 4e-11
Identities = 57/249 (22%), Positives = 101/249 (40%), Gaps = 10/249 (4%)
Query: 91 SLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKINNIS--DNAFENXXXXXXXXXDRN 147
++++L L +N IQ I + L L+ L L DN I+ + D AF +N
Sbjct: 156 NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKN 215
Query: 148 KLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQ--IPDNTF 205
L ++P L +L+ L + N + ++ + F++L L L + N L+ I + TF
Sbjct: 216 HLSSVPVGLPVDLQ---ELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTF 272
Query: 206 SDCFNLEKLDLSKNKLRFINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLD 265
S L++ + +N L + + AFS L+ L L +
Sbjct: 273 SHLTKLKEFSIVRNSLS--HPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDIS 330
Query: 266 GNMFPSLPSRTLDYMPKLTIVKLSGNPWHCDCHALYISAWVRLNEMKIWDYSPTCVSPWY 325
N L D + L + NPW CDC +++ W++ + C P
Sbjct: 331 NNQLRMLTQGVFDNLSNLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQ 390
Query: 326 LEGHFLKKL 334
+ G +++L
Sbjct: 391 VRGMAVREL 399
Score = 62.9 bits (146), Expect = 1e-08
Identities = 54/198 (27%), Positives = 93/198 (46%), Gaps = 10/198 (5%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSE--AFTSTKKLFHVDLSNNYLYTLPEK 60
+N+++ + L+ L+ L L N + + E AF L + LS N+L ++P
Sbjct: 164 ENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVG 223
Query: 61 LFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQN--IQNGTFS-LKNLQI 117
L + L+ + + NR+ + +F L SL+ L + N + N I GTFS L L+
Sbjct: 224 LPVD---LQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKE 280
Query: 118 LKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLA 177
+ N +++ + D N++ +IP F+NL+ L LD+SNN L L
Sbjct: 281 FSIVRNSLSHPPPD-LPGTHLIRLYLQD-NQINHIPLTAFSNLRKLERLDISNNQLRMLT 338
Query: 178 GVEFESLKLLRNLDLKEN 195
F++L L+ L + N
Sbjct: 339 QGVFDNLSNLKQLTARNN 356
Score = 62.1 bits (144), Expect = 2e-08
Identities = 56/207 (27%), Positives = 93/207 (44%), Gaps = 12/207 (5%)
Query: 19 NLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTL--PEKLFANNTFLETIDISNN 76
N++ L LQ N ++ I A KL + L +N + T+ + F L+ + +S N
Sbjct: 156 NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKN 215
Query: 77 RVVYVPSDSFLGL-YSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINN--ISDNA 132
+ VP +GL LQ L + +N+I I + F +L +L+ L + N + N I++
Sbjct: 216 HLSSVP----VGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGT 271
Query: 133 FENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDL 192
F + RN L + P L LI L L +N + + F +L+ L LD+
Sbjct: 272 FSHLTKLKEFSIVRNSLSHPPPDLPGTH--LIRLYLQDNQINHIPLTAFSNLRKLERLDI 329
Query: 193 KENALSQIPDNTFSDCFNLEKLDLSKN 219
N L + F + NL++L N
Sbjct: 330 SNNQLRMLTQGVFDNLSNLKQLTARNN 356
>AK001991-1|BAA92025.1| 273|Homo sapiens protein ( Homo sapiens
cDNA FLJ11129 fis, clone PLACE1006239, weakly similar to
BONE PROTEOGLYCAN II PRECURSOR. ).
Length = 273
Score = 74.5 bits (175), Expect = 4e-12
Identities = 52/182 (28%), Positives = 88/182 (48%), Gaps = 1/182 (0%)
Query: 18 VNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFANNTFLETIDISNNR 77
VNL L L +N L + + +L V L N L LPEK + + L+ + I++N
Sbjct: 92 VNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNL 151
Query: 78 VVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTF-SLKNLQILKLSDNKINNISDNAFENX 136
+ + +F+GL++L L L+ N++Q I + F +L NL+IL + +N I I D F+
Sbjct: 152 LSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPL 211
Query: 137 XXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKLLRNLDLKENA 196
L IP L+ L + +N L+ + V + + L+ LDL +N
Sbjct: 212 INLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNP 271
Query: 197 LS 198
++
Sbjct: 272 IN 273
Score = 60.1 bits (139), Expect = 8e-08
Identities = 43/155 (27%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
Query: 68 LETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQNGTFS-LKNLQILKLSDNKIN 126
L +D+S N + V + + + L + L +NK+ + S L NLQ L ++ N ++
Sbjct: 94 LTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLS 153
Query: 127 NISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVEFESLKL 186
IS AF + N+L+ I ++ F+ L L L + N ++ + + F+ L
Sbjct: 154 TISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLIN 213
Query: 187 LRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKL 221
LR+L + L++IPDN NLE + N+L
Sbjct: 214 LRSLVIAGINLTEIPDNALVGLENLESISFYDNRL 248
Score = 56.4 bits (130), Expect = 1e-06
Identities = 34/123 (27%), Positives = 61/123 (49%), Gaps = 2/123 (1%)
Query: 166 LDLSNNNLMSLAGVEFESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFIN 225
LDLS NNL S+ + + + L ++ L+EN L+++P+ S+ NL++L ++ N L I+
Sbjct: 97 LDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTIS 156
Query: 226 ITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPKLTI 285
AF G ++ K F L NL L + N P + + +++ P + +
Sbjct: 157 PGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGEN--PIIRIKDMNFKPLINL 214
Query: 286 VKL 288
L
Sbjct: 215 RSL 217
Score = 41.5 bits (93), Expect = 0.031
Identities = 26/99 (26%), Positives = 48/99 (48%)
Query: 4 NHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLFA 63
N ++ + F++L NL+ L + N + I F L + ++ L +P+
Sbjct: 174 NRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALV 233
Query: 64 NNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKI 102
LE+I +NR++ VP + + +L+ LDL+KN I
Sbjct: 234 GLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPI 272
>J04599-1|AAA36009.1| 368|Homo sapiens protein ( Human hPGI mRNA
encoding bone small proteoglycan I (biglycan), complete
cds. ).
Length = 368
Score = 72.9 bits (171), Expect = 1e-11
Identities = 58/229 (25%), Positives = 103/229 (44%), Gaps = 9/229 (3%)
Query: 3 DNHVEYLPGGIFESLVNLKTLRLQRNYLEEIDSEAFTSTKKLFHVDLSNNYLYTLPEKLF 62
+N + L F+ L +L L L N + +I +AF+ +KL + +S N+L +P L
Sbjct: 99 NNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLP 158
Query: 63 ANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQN--IQNGTFSLKNLQILKL 120
++ L + I +NR+ VP F GL ++ +++ N ++N + G F L L++
Sbjct: 159 SS---LVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRI 215
Query: 121 SDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIFLDLSNNNLMSLAGVE 180
S+ K+ I + E D NK++ I + L L L +N + +
Sbjct: 216 SEAKLTGIPKDLPE---TLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGS 272
Query: 181 FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLRFINITAF 229
L LR L L N L+++P D L+ + L N + + + F
Sbjct: 273 LSFLPTLRELHLDNNKLARVPSG-LPDLKLLQVVYLHSNNITKVGVNDF 320
Score = 64.9 bits (151), Expect = 3e-09
Identities = 67/249 (26%), Positives = 107/249 (42%), Gaps = 16/249 (6%)
Query: 47 VDLSNNYLYTLPEKLFANNTFLETIDISNNRVVYVPSDSFLGLYSLQILDLSKNKIQNIQ 106
V S+ L ++P+++ + T L D+ NN + + D F GL L L L NKI I
Sbjct: 74 VQCSDLGLKSVPKEISPDTTLL---DLQNNDISELRKDDFKGLQHLYALVLVNNKISKIH 130
Query: 107 NGTFS-LKNLQILKLSDNKINNISDNAFENXXXXXXXXXDRNKLKNIPTQLFNNLKCLIF 165
FS L+ LQ L +S N + I N N+++ +P +F+ L+ +
Sbjct: 131 EKAFSPLRKLQKLYISKNHLVEIPPNL---PSSLVELRIHDNRIRKVPKGVFSGLRNMNC 187
Query: 166 LDLSNNNLMSLAGVE---FESLKLLRNLDLKENALSQIPDNTFSDCFNLEKLDLSKNKLR 222
+++ N L + +G E F+ LK L L + E L+ IP + L +L L NK++
Sbjct: 188 IEMGGNPLEN-SGFEPGAFDGLK-LNYLRISEAKLTGIPKDLPE---TLNELHLDHNKIQ 242
Query: 223 FINITAFYGXXXXXXXXXXXXXXYEVHFKAFSMLKNLTTLYLDGNMFPSLPSRTLDYMPK 282
I + + + S L L L+LD N +PS D +
Sbjct: 243 AIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPD-LKL 301
Query: 283 LTIVKLSGN 291
L +V L N
Sbjct: 302 LQVVYLHSN 310
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.317 0.134 0.379
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 277,286,424
Number of Sequences: 224733
Number of extensions: 11386647
Number of successful extensions: 37038
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 588
Number of HSP's successfully gapped in prelim test: 235
Number of HSP's that attempted gapping in prelim test: 25818
Number of HSP's gapped (non-prelim): 5414
length of query: 2095
length of database: 73,234,838
effective HSP length: 101
effective length of query: 1994
effective length of database: 50,536,805
effective search space: 100770389170
effective search space used: 100770389170
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 73 (33.5 bits)
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