BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000375-TA|BGIBMGA000375-PA|IPR001269|Dihydrouridine synthase, DuS (222 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_UPI0000D5693C Cluster: PREDICTED: similar to dihydrouri... 258 1e-67 UniRef50_Q0IFC6 Cluster: tRNA-dihydrouridine synthase; n=2; Culi... 249 5e-65 UniRef50_UPI00015B403F Cluster: PREDICTED: similar to MGC79829 p... 245 8e-64 UniRef50_O95620 Cluster: tRNA-dihydrouridine synthase 4-like; n=... 216 4e-55 UniRef50_Q9VJ06 Cluster: CG10495-PA; n=2; Sophophora|Rep: CG1049... 214 2e-54 UniRef50_Q54ES7 Cluster: Putative uncharacterized protein; n=1; ... 177 2e-43 UniRef50_Q09504 Cluster: Uncharacterized tRNA-dihydrouridine syn... 174 1e-42 UniRef50_O74553 Cluster: tRNA dihydrouridine synthase Dus4; n=1;... 170 3e-41 UniRef50_A7EMF2 Cluster: Putative uncharacterized protein; n=1; ... 154 2e-36 UniRef50_Q5A4Y0 Cluster: Potential tRNA dihydrouridine synthase;... 153 3e-36 UniRef50_Q06063 Cluster: tRNA-dihydrouridine synthase 4; n=10; S... 146 4e-34 UniRef50_Q583Y8 Cluster: TRNA-dihydrouridine synthase 4, putativ... 145 9e-34 UniRef50_Q4Q391 Cluster: Putative uncharacterized protein; n=3; ... 134 1e-30 UniRef50_A5K1E0 Cluster: tRNA-dihydrouridine synthase, putative;... 128 8e-29 UniRef50_Q54XQ6 Cluster: Putative uncharacterized protein; n=1; ... 127 2e-28 UniRef50_Q9FH91 Cluster: Gb|AAF51525.1; n=6; Magnoliophyta|Rep: ... 123 3e-27 UniRef50_Q9VPM1 Cluster: CG3645-PA, isoform A; n=2; Diptera|Rep:... 123 3e-27 UniRef50_A7AQM0 Cluster: Dihydrouridine synthase, putative; n=1;... 122 5e-27 UniRef50_Q9XVN8 Cluster: Putative uncharacterized protein; n=2; ... 122 9e-27 UniRef50_Q5KPM6 Cluster: Putative uncharacterized protein; n=2; ... 121 1e-26 UniRef50_A4S141 Cluster: Predicted protein; n=1; Ostreococcus lu... 121 2e-26 UniRef50_Q5CSA9 Cluster: Dus1p, tRNA dihydrouridine synthase; n=... 117 2e-25 UniRef50_Q6P1R4 Cluster: tRNA-dihydrouridine synthase 1-like; n=... 115 8e-25 UniRef50_A0EG06 Cluster: Chromosome undetermined scaffold_94, wh... 112 8e-24 UniRef50_A2FU21 Cluster: Putative uncharacterized protein; n=1; ... 110 2e-23 UniRef50_UPI000023CFE7 Cluster: hypothetical protein FG01258.1; ... 105 9e-22 UniRef50_Q4UGK9 Cluster: Putative uncharacterized protein; n=2; ... 104 2e-21 UniRef50_P53759 Cluster: tRNA-dihydrouridine synthase 1; n=11; S... 103 4e-21 UniRef50_UPI0000499E32 Cluster: conserved hypothetical protein; ... 101 1e-20 UniRef50_Q9HGN6 Cluster: tRNA dihydrouridine synthase Dus1; n=1;... 100 3e-20 UniRef50_A2EF32 Cluster: Dihydrouridine synthase, putative; n=1;... 99 8e-20 UniRef50_Q8SUV4 Cluster: Putative uncharacterized protein ECU07_... 99 8e-20 UniRef50_Q8PX79 Cluster: NifR3-like protein; n=5; Archaea|Rep: N... 98 1e-19 UniRef50_A2DHB4 Cluster: Putative uncharacterized protein; n=1; ... 97 2e-19 UniRef50_Q00RI1 Cluster: OSIGBa0125M19.5 protein; n=9; Magnoliop... 96 7e-19 UniRef50_A6DCX2 Cluster: tRNA-dihydrouridine synthase B; n=1; Ca... 95 9e-19 UniRef50_A4RU69 Cluster: Predicted protein; n=2; Ostreococcus|Re... 95 9e-19 UniRef50_Q4PBU9 Cluster: Putative uncharacterized protein; n=1; ... 95 1e-18 UniRef50_Q57V78 Cluster: TRNA-dihydrouridine synthase 1, putativ... 91 2e-17 UniRef50_UPI000023EA9A Cluster: hypothetical protein FG07217.1; ... 90 5e-17 UniRef50_A6RW05 Cluster: Putative uncharacterized protein; n=1; ... 89 8e-17 UniRef50_Q6F288 Cluster: TRNA dihydrouridine synthetase; n=3; Mo... 89 1e-16 UniRef50_A2EN54 Cluster: Putative uncharacterized protein; n=1; ... 89 1e-16 UniRef50_Q4PG83 Cluster: Putative uncharacterized protein; n=1; ... 88 2e-16 UniRef50_A2F0D1 Cluster: Putative uncharacterized protein; n=1; ... 85 1e-15 UniRef50_A4M5I1 Cluster: Dihydrouridine synthase, DuS; n=1; Petr... 84 2e-15 UniRef50_Q5KP54 Cluster: TRNA dihydrouridine synthase, putative;... 84 2e-15 UniRef50_Q9XWJ9 Cluster: Putative uncharacterized protein; n=2; ... 83 7e-15 UniRef50_A2ACC0 Cluster: Novel protein; n=17; Eumetazoa|Rep: Nov... 82 9e-15 UniRef50_Q4D174 Cluster: Dihydrouridine synthase (Dus), putative... 82 1e-14 UniRef50_Q7SGX4 Cluster: Putative uncharacterized protein NCU031... 81 2e-14 UniRef50_Q6AJZ5 Cluster: TRNA-dihydrouridine synthase; n=1; Desu... 80 4e-14 UniRef50_Q4WRF0 Cluster: Dihydrouridine synthase family protein,... 79 7e-14 UniRef50_Q9NX74 Cluster: tRNA-dihydrouridine synthase 2-like; n=... 79 9e-14 UniRef50_A2FJB5 Cluster: TIM-barrel protein, nifR3 family protei... 79 1e-13 UniRef50_Q54QJ2 Cluster: Putative uncharacterized protein; n=1; ... 78 2e-13 UniRef50_Q5KGP0 Cluster: Putative uncharacterized protein; n=3; ... 78 2e-13 UniRef50_UPI00015B40A4 Cluster: PREDICTED: similar to tRNA-dihyd... 77 3e-13 UniRef50_Q7RX85 Cluster: Putative uncharacterized protein NCU000... 77 3e-13 UniRef50_Q59YG4 Cluster: Potential tRNA dihydrouridine synthase;... 76 6e-13 UniRef50_Q1NXZ7 Cluster: Dihydrouridine synthase TIM-barrel prot... 75 1e-12 UniRef50_Q8RFK3 Cluster: Nitrogen regulation protein NIFR3; n=3;... 75 2e-12 UniRef50_Q2H6D9 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12 UniRef50_Q8KB61 Cluster: TIM-barrel protein, nifR3 family; n=10;... 74 3e-12 UniRef50_Q9VY45 Cluster: CG1434-PA; n=6; Endopterygota|Rep: CG14... 73 4e-12 UniRef50_Q4S086 Cluster: Chromosome undetermined SCAF14784, whol... 73 6e-12 UniRef50_Q6C002 Cluster: Yarrowia lipolytica chromosome F of str... 73 7e-12 UniRef50_O74731 Cluster: tRNA dihydrouridine synthase Dus2; n=1;... 73 7e-12 UniRef50_A4RL93 Cluster: Putative uncharacterized protein; n=1; ... 73 7e-12 UniRef50_A6DPY9 Cluster: Putative uncharacterized protein; n=1; ... 72 1e-11 UniRef50_Q74EF7 Cluster: Dihydrouridine synthase family protein;... 72 1e-11 UniRef50_Q31II6 Cluster: Dihydrouridine synthase; n=1; Thiomicro... 71 2e-11 UniRef50_A4XH30 Cluster: Putative TIM-barrel protein, nifR3 fami... 71 2e-11 UniRef50_A5DYF6 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-11 UniRef50_A1SX05 Cluster: Dihydrouridine synthase, DuS; n=3; Alte... 71 2e-11 UniRef50_Q550J6 Cluster: Putative uncharacterized protein; n=2; ... 71 2e-11 UniRef50_Q4PIC3 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-11 UniRef50_Q7MXX6 Cluster: TIM-barrel protein, putative, NifR3 fam... 71 3e-11 UniRef50_Q6BX60 Cluster: Debaryomyces hansenii chromosome B of s... 71 3e-11 UniRef50_O67533 Cluster: Probable tRNA-dihydrouridine synthase; ... 71 3e-11 UniRef50_Q899H0 Cluster: Nitrogen regulation protein nifR3; n=24... 70 4e-11 UniRef50_Q47C15 Cluster: Dihydrouridine synthase, DuS; n=2; Beta... 70 4e-11 UniRef50_Q1IVR5 Cluster: Dihydrouridine synthase TIM-barrel prot... 70 5e-11 UniRef50_A6BZR9 Cluster: Predicted TIM-barrel enzyme, possibly d... 70 5e-11 UniRef50_A6CBK4 Cluster: Predicted TIM-barrel enzyme, possibly d... 69 7e-11 UniRef50_Q6SFW7 Cluster: NifR3/Smm1 family protein; n=1; uncultu... 69 9e-11 UniRef50_Q0YFW9 Cluster: Dihydrouridine synthase TIM-barrel prot... 69 9e-11 UniRef50_A2DYY3 Cluster: Putative uncharacterized protein; n=1; ... 69 1e-10 UniRef50_Q5ZRM0 Cluster: Nitrogen regulation protein; n=4; Legio... 68 2e-10 UniRef50_Q0FAI7 Cluster: tRNA-dihydrouridine synthase, putative;... 68 2e-10 UniRef50_Q14SX5 Cluster: Putative dihydrouridine synthase; n=1; ... 67 3e-10 UniRef50_Q5M689 Cluster: Possible transcriptional regulator; n=2... 66 5e-10 UniRef50_A0LJ96 Cluster: Putative TIM-barrel protein, nifR3 fami... 66 5e-10 UniRef50_Q64MI4 Cluster: Putative TIM-barrel enzyme; n=3; Bacter... 66 7e-10 UniRef50_Q6MNE4 Cluster: Dihydrouridine synthase family protein;... 66 9e-10 UniRef50_Q0B0N8 Cluster: Putative TIM-barrel protein, NifR3 fami... 66 9e-10 UniRef50_Q9JUP6 Cluster: tRNA-dihydrouridine synthase C; n=4; Ne... 66 9e-10 UniRef50_Q8ZAX7 Cluster: tRNA-dihydrouridine synthase B; n=214; ... 66 9e-10 UniRef50_P37567 Cluster: Probable tRNA-dihydrouridine synthase 1... 66 9e-10 UniRef50_A6LGT0 Cluster: Putative TIM-barrel enzyme; n=1; Paraba... 65 1e-09 UniRef50_Q7R3H4 Cluster: GLP_158_49916_51304; n=1; Giardia lambl... 65 1e-09 UniRef50_A2QES0 Cluster: Contig An02c0390, complete genome; n=12... 65 1e-09 UniRef50_Q6MNE9 Cluster: Nitrogen regulation protein nifR3; n=1;... 65 2e-09 UniRef50_Q6AKJ6 Cluster: Putative uncharacterized protein; n=1; ... 65 2e-09 UniRef50_Q1Q3Q8 Cluster: Strongly similar to tRNA-dihydrouridine... 64 3e-09 UniRef50_Q1DPY5 Cluster: Putative uncharacterized protein; n=1; ... 64 3e-09 UniRef50_Q7VKU5 Cluster: tRNA-dihydrouridine synthase C; n=118; ... 64 3e-09 UniRef50_Q607L4 Cluster: TIM-barrel protein, yjbN family; n=10; ... 64 3e-09 UniRef50_Q0G7A4 Cluster: Nitrogen regulation protein nifr3; n=2;... 64 3e-09 UniRef50_Q127F8 Cluster: Dihydrouridine synthase, DuS; n=3; Prot... 63 6e-09 UniRef50_Q7R1J1 Cluster: GLP_38_15456_16676; n=1; Giardia lambli... 63 6e-09 UniRef50_Q9CLW3 Cluster: tRNA-dihydrouridine synthase B; n=17; P... 63 6e-09 UniRef50_P53720 Cluster: tRNA-dihydrouridine synthase 2; n=7; Sa... 63 6e-09 UniRef50_Q8XYX1 Cluster: tRNA-dihydrouridine synthase C; n=26; P... 62 8e-09 UniRef50_O52532 Cluster: tRNA-dihydrouridine synthase B; n=6; Ga... 62 8e-09 UniRef50_A3RPJ2 Cluster: TRNA-dihydrouridine synthase; n=2; Prot... 62 1e-08 UniRef50_Q4PAE4 Cluster: Putative uncharacterized protein; n=1; ... 62 1e-08 UniRef50_A7EHJ6 Cluster: Putative uncharacterized protein; n=2; ... 62 1e-08 UniRef50_A6R3V4 Cluster: Putative uncharacterized protein; n=1; ... 62 1e-08 UniRef50_Q08111 Cluster: Probable tRNA-dihydrouridine synthase; ... 62 1e-08 UniRef50_Q3AZ67 Cluster: Dihydrouridine synthase TIM-barrel prot... 61 2e-08 UniRef50_Q2RM54 Cluster: Dihydrouridine synthase TIM-barrel prot... 61 2e-08 UniRef50_Q22A31 Cluster: TIM-barrel protein, yjbN family; n=1; T... 61 2e-08 UniRef50_O25427 Cluster: Probable tRNA-dihydrouridine synthase; ... 61 2e-08 UniRef50_Q8YAB9 Cluster: Lmo0227 protein; n=55; Bacteria|Rep: Lm... 61 2e-08 UniRef50_Q7XWZ9 Cluster: OSJNBa0079F16.4 protein; n=8; Oryza sat... 61 2e-08 UniRef50_Q6PEH0 Cluster: Zgc:63779; n=8; Chordata|Rep: Zgc:63779... 60 3e-08 UniRef50_A4SY29 Cluster: Dihydrouridine synthase, DuS; n=1; Poly... 59 7e-08 UniRef50_A6U9Y2 Cluster: Dihydrouridine synthase DuS; n=2; Sinor... 59 1e-07 UniRef50_A4S604 Cluster: Predicted protein; n=1; Ostreococcus lu... 59 1e-07 UniRef50_Q54CU9 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07 UniRef50_A7CWF1 Cluster: Putative TIM-barrel protein, nifR3 fami... 58 1e-07 UniRef50_Q9TYN2 Cluster: Putative uncharacterized protein Y37E11... 58 1e-07 UniRef50_Q9ZED2 Cluster: Probable tRNA-dihydrouridine synthase; ... 58 1e-07 UniRef50_Q9RRP8 Cluster: NifR3 protein; n=2; Deinococcus|Rep: Ni... 58 2e-07 UniRef50_Q3IKP0 Cluster: TRNA-dihydrouridine synthase C; n=5; Al... 58 2e-07 UniRef50_A1VHK2 Cluster: Dihydrouridine synthase, DuS; n=4; Desu... 58 2e-07 UniRef50_Q5SMC7 Cluster: TRNA-dihydrouridine synthase; n=2; Ther... 58 2e-07 UniRef50_Q5LQV9 Cluster: TRNA-dihydrouridine synthase A; n=46; B... 58 2e-07 UniRef50_Q4FQ57 Cluster: Possible tRNA-dihydrouridine synthase; ... 58 2e-07 UniRef50_Q1QZQ6 Cluster: Dihydrouridine synthase, DuS; n=1; Chro... 58 2e-07 UniRef50_A6W1E8 Cluster: Dihydrouridine synthase DuS; n=1; Marin... 58 2e-07 UniRef50_Q96G46 Cluster: tRNA-dihydrouridine synthase 3-like; n=... 58 2e-07 UniRef50_Q8GQD1 Cluster: NifR; n=5; Leptospira|Rep: NifR - Lepto... 57 3e-07 UniRef50_A3JG66 Cluster: Putative uncharacterized protein; n=3; ... 57 3e-07 UniRef50_A5D5Q0 Cluster: TRNA-dihydrouridine synthase; n=5; Firm... 57 4e-07 UniRef50_Q9LY64 Cluster: Putative uncharacterized protein MAA21_... 57 4e-07 UniRef50_Q9Z7D8 Cluster: Predicted oxidoreductase; n=7; Chlamydi... 56 7e-07 UniRef50_Q5LRN6 Cluster: TRNA-dihydrouridine synthase, putative;... 56 7e-07 UniRef50_Q4QEF9 Cluster: Putative uncharacterized protein; n=3; ... 56 7e-07 UniRef50_A4EC62 Cluster: Putative uncharacterized protein; n=1; ... 56 9e-07 UniRef50_Q251N6 Cluster: Putative uncharacterized protein; n=2; ... 55 1e-06 UniRef50_Q55724 Cluster: Probable tRNA-dihydrouridine synthase 1... 55 1e-06 UniRef50_Q1VN28 Cluster: Dihydrouridine synthase TIM-barrel prot... 55 2e-06 UniRef50_Q7R9R0 Cluster: Uncharacterized protein family UPF0034,... 55 2e-06 UniRef50_Q7R684 Cluster: GLP_574_116690_118078; n=1; Giardia lam... 54 2e-06 UniRef50_Q21L63 Cluster: Dihydrouridine synthase, DuS; n=1; Sacc... 54 3e-06 UniRef50_A7DPL5 Cluster: Putative TIM-barrel protein, nifR3 fami... 54 3e-06 UniRef50_UPI00015B6197 Cluster: PREDICTED: similar to CG10463-PA... 54 4e-06 UniRef50_Q0VPD7 Cluster: TIM-barrel protein, yjbN family; n=4; B... 54 4e-06 UniRef50_Q91XI1 Cluster: tRNA-dihydrouridine synthase 3-like; n=... 54 4e-06 UniRef50_A4RQU5 Cluster: Predicted protein; n=2; Ostreococcus|Re... 53 5e-06 UniRef50_Q8YMN5 Cluster: Transcriptional regulator; n=5; Bacteri... 53 6e-06 UniRef50_Q6MAU6 Cluster: Putative uncharacterized protein yohI; ... 53 6e-06 UniRef50_Q4FLD8 Cluster: Putative uncharacterized protein; n=2; ... 53 6e-06 UniRef50_Q30WR3 Cluster: Dihydrouridine synthase family protein;... 53 6e-06 UniRef50_A6NW05 Cluster: Putative uncharacterized protein; n=1; ... 53 6e-06 UniRef50_A6GHV6 Cluster: Dihydrouridine synthase family protein;... 53 6e-06 UniRef50_Q5CRK5 Cluster: Ylr401cp-like protein with 2 CCCH domai... 53 6e-06 UniRef50_A7S213 Cluster: Predicted protein; n=1; Nematostella ve... 53 6e-06 UniRef50_O83945 Cluster: Probable tRNA-dihydrouridine synthase; ... 53 6e-06 UniRef50_Q6MRF1 Cluster: Transcription regulator homolog yacF; n... 52 9e-06 UniRef50_Q3E0H8 Cluster: Dihydrouridine synthase TIM-barrel prot... 52 9e-06 UniRef50_Q884C6 Cluster: tRNA-dihydrouridine synthase C; n=8; Pr... 52 9e-06 UniRef50_Q489F6 Cluster: NifR3/Smm1 family protein; n=2; Proteob... 52 1e-05 UniRef50_Q1N033 Cluster: Putative uncharacterized protein; n=1; ... 52 1e-05 UniRef50_Q056Y8 Cluster: TRNA-dihydrouridine synthase A; n=1; Bu... 52 1e-05 UniRef50_A1RNI1 Cluster: TIM-barrel protein, yjbN family; n=30; ... 52 1e-05 UniRef50_A3LUK5 Cluster: Dihydrouridine synthase of tRNA; n=6; S... 52 1e-05 UniRef50_UPI0000499494 Cluster: conserved hypothetical protein; ... 51 2e-05 UniRef50_Q012U0 Cluster: Nitrogen regulation family protein; n=2... 51 2e-05 UniRef50_A7HK00 Cluster: Dihydrouridine synthase DuS; n=4; Therm... 51 3e-05 UniRef50_A4BCJ5 Cluster: NifR3/Smm1 family protein; n=2; Gammapr... 51 3e-05 UniRef50_A4AAB0 Cluster: TRNA-dihydrouridine synthase C; n=2; un... 51 3e-05 UniRef50_UPI0000E472BC Cluster: PREDICTED: similar to tRNA-dihyd... 50 3e-05 UniRef50_Q2UL89 Cluster: Uncharacterized conserved protein; n=15... 50 3e-05 UniRef50_A6DU09 Cluster: Dihydrouridine synthase family protein;... 50 5e-05 UniRef50_Q89LQ7 Cluster: Nitrogen regulation protein; n=22; Alph... 50 6e-05 UniRef50_O51243 Cluster: Putative uncharacterized protein BB0225... 50 6e-05 UniRef50_Q1JWD3 Cluster: Dihydrouridine synthase, DuS; n=1; Desu... 50 6e-05 UniRef50_Q9V0Y6 Cluster: Dihydroorotate dehydrogenase; n=8; Eury... 50 6e-05 UniRef50_Q7UXK8 Cluster: Putative uncharacterized protein; n=3; ... 49 8e-05 UniRef50_Q6M9N8 Cluster: Putative uncharacterized protein; n=1; ... 49 8e-05 UniRef50_A6EDJ3 Cluster: Probable TIM-barrel protein, NifR3 fami... 49 8e-05 UniRef50_Q9FI41 Cluster: Emb|CAB87804.1; n=7; Magnoliophyta|Rep:... 49 8e-05 UniRef50_Q0F181 Cluster: Dihydrouridine synthase TIM-barrel prot... 49 1e-04 UniRef50_Q04VP3 Cluster: TRNA-dihydrouridine synthase; n=4; Lept... 49 1e-04 UniRef50_A5EVV4 Cluster: Dihydrouridine synthase; n=1; Dicheloba... 49 1e-04 UniRef50_A4TZK1 Cluster: Dihydrouridine synthase, DuS; n=4; Prot... 49 1e-04 UniRef50_A1AW94 Cluster: TIM-barrel protein, yjbN family; n=1; C... 49 1e-04 UniRef50_Q5HJT5 Cluster: Probable tRNA-dihydrouridine synthase; ... 49 1e-04 UniRef50_A1IF01 Cluster: Dihydrouridine synthase family protein;... 48 1e-04 UniRef50_Q7X346 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04 UniRef50_UPI0000DAE45A Cluster: hypothetical protein Rgryl_01000... 48 2e-04 UniRef50_Q2RZL4 Cluster: NifR3 family enzyme; n=1; Salinibacter ... 48 2e-04 UniRef50_Q7UBC5 Cluster: tRNA-dihydrouridine synthase A; n=231; ... 48 2e-04 UniRef50_Q2NEG1 Cluster: PyrD; n=1; Methanosphaera stadtmanae DS... 47 3e-04 UniRef50_Q2IG49 Cluster: Dihydrouridine synthase TIM-barrel prot... 47 4e-04 UniRef50_Q4Q231 Cluster: Dihydrouridine synthase domain protein-... 47 4e-04 UniRef50_A1AT39 Cluster: Dihydrouridine synthase, DuS; n=7; Desu... 46 6e-04 UniRef50_Q06053 Cluster: tRNA-dihydrouridine synthase 3; n=6; Sa... 46 7e-04 UniRef50_Q5ZVH8 Cluster: Zinc binding TIM barrel protein, YjbN f... 46 0.001 UniRef50_Q8SUY1 Cluster: Putative uncharacterized protein ECU07_... 46 0.001 UniRef50_Q6AJ40 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002 UniRef50_A5GPV9 Cluster: TRNA-dihydrouridine synthase A; n=21; C... 45 0.002 UniRef50_A0EAZ6 Cluster: Chromosome undetermined scaffold_87, wh... 45 0.002 UniRef50_O31546 Cluster: Probable tRNA-dihydrouridine synthase 2... 45 0.002 UniRef50_UPI000058804E Cluster: PREDICTED: similar to MGC53781 p... 44 0.002 UniRef50_Q2RTR9 Cluster: Dihydrouridine synthase TIM-barrel prot... 44 0.002 UniRef50_A4RVX6 Cluster: Predicted protein; n=2; Ostreococcus|Re... 44 0.002 UniRef50_Q9VIS4 Cluster: CG10463-PA; n=3; Sophophora|Rep: CG1046... 44 0.002 UniRef50_Q7UKE8 Cluster: Putative uncharacterized protein; n=2; ... 44 0.003 UniRef50_A1IED4 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003 UniRef50_Q01ML2 Cluster: H0613H07.1 protein; n=10; Eukaryota|Rep... 44 0.004 UniRef50_Q5FTP7 Cluster: Nitrogen assimilation regulatory protei... 43 0.005 UniRef50_A6PPM6 Cluster: Dihydrouridine synthase, DuS; n=1; Vict... 43 0.005 UniRef50_A5N517 Cluster: Predicted NADH oxidase; n=1; Clostridiu... 43 0.005 UniRef50_Q2HDP2 Cluster: Putative uncharacterized protein; n=1; ... 43 0.005 UniRef50_A0Z3E6 Cluster: Dihydroorotate dehydrogenase/oxidoreduc... 43 0.007 UniRef50_Q582L4 Cluster: TRNA-dihydrouridine synthase 3, putativ... 43 0.007 UniRef50_Q8A2H9 Cluster: Putative nifR3 family TIM-barrel enzyme... 42 0.009 UniRef50_Q83D40 Cluster: TIM-barrel protein, yjbN family; n=7; B... 42 0.012 UniRef50_A5FPW7 Cluster: Dihydroorotate dehydrogenase family pro... 42 0.012 UniRef50_Q9UTH9 Cluster: tRNA dihydrouridine synthase Dus3; n=1;... 42 0.012 UniRef50_A7DKP5 Cluster: Dihydrouridine synthase, DuS; n=2; Meth... 42 0.016 UniRef50_A4BWB1 Cluster: Putative uncharacterized protein; n=5; ... 41 0.021 UniRef50_A7AWB5 Cluster: Dihydrouridine synthase (Dus) domain co... 41 0.021 UniRef50_Q9PGB5 Cluster: tRNA-dihydrouridine synthase A; n=8; Pr... 41 0.021 UniRef50_Q979G6 Cluster: Dihydroorotate dehydrogenase; n=4; Ther... 41 0.028 UniRef50_Q38BB4 Cluster: TRNA-dihydrouridine synthase 2, putativ... 40 0.037 UniRef50_Q8G7W8 Cluster: Possible NifR3-like protein; n=4; Bifid... 40 0.049 UniRef50_Q0C0N1 Cluster: Putative tRNA-dihydrouridine synthase; ... 40 0.049 UniRef50_Q6C4K3 Cluster: Similar to DEHA0D12364g Debaryomyces ha... 40 0.049 UniRef50_Q7PVV7 Cluster: ENSANGP00000016833; n=2; Endopterygota|... 40 0.065 UniRef50_Q9K9W1 Cluster: Dihydroorotate dehydrogenase; n=1; Baci... 40 0.065 UniRef50_Q73P17 Cluster: Dihydroorotate dehydrogenase/oxidoreduc... 39 0.085 UniRef50_Q090Q9 Cluster: TRNA-dihydrouridine synthase B; n=2; Cy... 39 0.085 UniRef50_A6GGZ7 Cluster: Putative uncharacterized protein; n=2; ... 39 0.085 UniRef50_A5KKR3 Cluster: Putative uncharacterized protein; n=1; ... 39 0.085 UniRef50_Q4Q669 Cluster: Dihydrouridine synthase (Dus), putative... 39 0.085 UniRef50_Q8TXU6 Cluster: Dihydroorotate dehydrogenase; n=1; Meth... 39 0.085 UniRef50_Q73RG6 Cluster: Dihydrouridine synthase, putative; n=1;... 39 0.11 UniRef50_A5WG83 Cluster: TIM-barrel protein, yjbN family; n=4; M... 39 0.11 UniRef50_O53835 Cluster: Probable tRNA-dihydrouridine synthase; ... 39 0.11 UniRef50_A5EXU5 Cluster: TRNA-dihydrouridine synthase A; n=1; Di... 38 0.15 UniRef50_A1X3A1 Cluster: Putative NADH:flavin oxidoreductase; n=... 38 0.15 UniRef50_Q17M24 Cluster: tRNA-dihydrouridine synthase; n=1; Aede... 38 0.15 UniRef50_A7IA09 Cluster: Thiamine-phosphate pyrophosphorylase; n... 38 0.15 UniRef50_Q97DM0 Cluster: Predicted TIM-barrel enzyme, nifR3 fami... 38 0.20 UniRef50_O51679 Cluster: Histidine phosphokinase/phophatase, put... 38 0.20 UniRef50_Q9RDC6 Cluster: Putative uncharacterized protein SCO249... 38 0.26 UniRef50_Q1EYG5 Cluster: NADH:flavin oxidoreductase/NADH oxidase... 38 0.26 UniRef50_A4S3Q5 Cluster: Predicted protein; n=2; Eukaryota|Rep: ... 37 0.34 UniRef50_Q8PW56 Cluster: Dihydroorotate dehydrogenase; n=14; Eur... 37 0.46 UniRef50_A2DZN8 Cluster: Oxidoreductase, FAD/FMN-binding family ... 36 0.60 UniRef50_Q5KC68 Cluster: TRNA dihydrouridine synthase, putative;... 36 0.60 UniRef50_Q9A7I4 Cluster: Nitrogen regulation protein Nifr3; n=2;... 36 0.80 UniRef50_Q97K75 Cluster: NADH:flavin oxidoreductase, possible NA... 36 0.80 UniRef50_A4YUQ6 Cluster: Putative tRNA-dihydrouridine synthase; ... 36 0.80 UniRef50_A4EV41 Cluster: Oxidoreductase, FAD/FMN-binding protein... 36 0.80 UniRef50_Q24833 Cluster: Putative nitrogen fixation regulatory p... 36 0.80 UniRef50_Q1G992 Cluster: Dihydroorotate dehydrogenase; n=3; Lact... 36 1.1 UniRef50_Q8ESS1 Cluster: 1-(5-phosphoribosyl)-5-[(5-phosphoribos... 36 1.1 UniRef50_Q4AHG7 Cluster: Dihydrouridine synthase, DuS; n=1; Chlo... 35 1.4 UniRef50_A7BE39 Cluster: Putative uncharacterized protein; n=1; ... 35 1.4 UniRef50_Q0AWX0 Cluster: NADH:flavin oxidoreductase, Old Yellow ... 35 1.8 UniRef50_Q010A0 Cluster: tRNA-dihydrouridine synthase; n=1; Ostr... 35 1.8 UniRef50_A6P2M8 Cluster: Putative uncharacterized protein; n=1; ... 34 2.4 UniRef50_A3VNG3 Cluster: Dihydrouridine synthase TIM-barrel prot... 34 2.4 UniRef50_A2DV72 Cluster: 4Fe-4S binding domain containing protei... 34 2.4 UniRef50_A0LHK5 Cluster: 1-(5-phosphoribosyl)-5-[(5-phosphoribos... 34 2.4 UniRef50_Q65PP9 Cluster: Lj928 prophage protein; n=24; root|Rep:... 34 3.2 UniRef50_Q09E70 Cluster: Thiazole biosynthesis protein ThiG; n=1... 34 3.2 UniRef50_A7AAN4 Cluster: Putative uncharacterized protein; n=2; ... 33 4.2 UniRef50_A0DW78 Cluster: Chromosome undetermined scaffold_662, w... 33 4.2 UniRef50_A6VYA3 Cluster: TIM-barrel protein, yjbN family; n=8; P... 33 5.6 UniRef50_Q8RI59 Cluster: Thiamine-phosphate pyrophosphorylase; n... 33 5.6 UniRef50_O29513 Cluster: Dihydroorotate dehydrogenase; n=1; Arch... 33 5.6 UniRef50_Q193G0 Cluster: DnaQ family exonuclease/DinG family hel... 32 9.8 UniRef50_A1BEJ0 Cluster: NADH:flavin oxidoreductase/NADH oxidase... 32 9.8 UniRef50_Q013U5 Cluster: CG3645-PB, isoform B; n=1; Ostreococcus... 32 9.8 UniRef50_A2DPI6 Cluster: Putative uncharacterized protein; n=1; ... 32 9.8 UniRef50_Q0CTZ8 Cluster: Putative uncharacterized protein; n=2; ... 32 9.8 UniRef50_Q466J2 Cluster: NADH-dependent flavine oxidoreductase; ... 32 9.8 >UniRef50_UPI0000D5693C Cluster: PREDICTED: similar to dihydrouridine synthase 4-like; n=3; Coelomata|Rep: PREDICTED: similar to dihydrouridine synthase 4-like - Tribolium castaneum Length = 451 Score = 258 bits (631), Expect = 1e-67 Identities = 119/216 (55%), Positives = 158/216 (73%), Gaps = 4/216 (1%) Query: 1 MKEICDIMEKFADAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQN 60 +K D+M+ FAD KI +K+CAPMVRYSK+ FR LV+++N DLC+TPMILADSFC++ Sbjct: 9 LKHSTDVMQLFADKKI----VKICAPMVRYSKLQFRNLVKSYNCDLCYTPMILADSFCKS 64 Query: 61 SKARANEFMTTTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYG 120 KARANEF T D P+I QFAAN DFV A+ +V P+ DGVDLNCGCPQ+WA G G Sbjct: 65 GKARANEFTTNMNDTPLITQFAANKVYDFVGAAYMVSPFCDGVDLNCGCPQRWAKLQGLG 124 Query: 121 CSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEE 180 C +L KPE+IYD+VK RNV+P F++SVK+RL D++++V +C+QLE CGV+FLT Sbjct: 125 CIMLEKPEVIYDLVKQCRNVIPKPFTVSVKLRLQKDLRRSVEICRQLEHCGVSFLTVHGR 184 Query: 181 HCTKSSGPVDINGLKEVREALSVPMVANGGVKHLND 216 + +G V+ L + +++VP+VANGGVK L D Sbjct: 185 TPDQLTGEVNKEALNLIVGSVNVPVVANGGVKSLED 220 >UniRef50_Q0IFC6 Cluster: tRNA-dihydrouridine synthase; n=2; Culicidae|Rep: tRNA-dihydrouridine synthase - Aedes aegypti (Yellowfever mosquito) Length = 391 Score = 249 bits (609), Expect = 5e-65 Identities = 114/209 (54%), Positives = 153/209 (73%), Gaps = 2/209 (0%) Query: 11 FADAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMT 70 F +A+ +YLK+CAPMVRYSK+ FR LVR++ DL FT MI+ADSFCQ+ KAR NEF T Sbjct: 14 FREARAKDSYLKICAPMVRYSKLEFRNLVRSYGTDLTFTSMIMADSFCQSEKARLNEFTT 73 Query: 71 TTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEII 130 D PVIAQFAA N DF+ A+++ +PYVDGVDLNCGCPQ+WAM+DGYG +LL PE+I Sbjct: 74 NRDDTPVIAQFAAKNAVDFLSATEMTFPYVDGVDLNCGCPQRWAMQDGYGSALLRTPELI 133 Query: 131 YDIVKGLRNVLPNKFSISVKIRLL-NDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGP 188 D++ +R LP+ FS+SVK+RLL + T+ +C+QLE CG+TF+T K++ P Sbjct: 134 ADMLSTVRRNLPSTFSVSVKVRLLQKSLSATIDMCRQLEACGITFITVHGRTPAQKTNIP 193 Query: 189 VDINGLKEVREALSVPMVANGGVKHLNDA 217 V+ LKE++ +L +P+VANG + L DA Sbjct: 194 VNQEALKEIKSSLGIPVVANGDIFSLQDA 222 >UniRef50_UPI00015B403F Cluster: PREDICTED: similar to MGC79829 protein; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to MGC79829 protein - Nasonia vitripennis Length = 346 Score = 245 bits (599), Expect = 8e-64 Identities = 110/198 (55%), Positives = 147/198 (74%) Query: 22 KVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQF 81 KVCAPMVRYSK+ FRTLVR ++ D+CFTPMILADSF Q+SKAR +EF T D P+I QF Sbjct: 16 KVCAPMVRYSKLPFRTLVRKYDCDICFTPMILADSFVQSSKARDSEFSTNEGDSPLIVQF 75 Query: 82 AANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141 AA DDFV+A+++V PY +GVDLNCGCPQ+WA+KDGYG LL+KP+++ ++V +RN + Sbjct: 76 AAKEVDDFVEATEMVAPYSNGVDLNCGCPQRWALKDGYGADLLTKPQLVKELVSNVRNRI 135 Query: 142 PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSGPVDINGLKEVREAL 201 P F++SVKIR+L DIKKT+ + +E GV+FLT + P+D++ LK VR + Sbjct: 136 PKPFTVSVKIRILKDIKKTIEFSRAIEHAGVSFLTVHARTPDMRNEPIDLDSLKLVRSCV 195 Query: 202 SVPMVANGGVKHLNDATT 219 +PM+ANG V+ DA T Sbjct: 196 HLPMIANGNVRSFEDAKT 213 >UniRef50_O95620 Cluster: tRNA-dihydrouridine synthase 4-like; n=28; Eumetazoa|Rep: tRNA-dihydrouridine synthase 4-like - Homo sapiens (Human) Length = 317 Score = 216 bits (527), Expect = 4e-55 Identities = 96/198 (48%), Positives = 144/198 (72%), Gaps = 1/198 (0%) Query: 21 LKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQ 80 +KVCAPMVRYSK+ FRTLVR ++ DLC+TPMI+A F ++ KAR +EF T D P+I Q Sbjct: 28 VKVCAPMVRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSIKARDSEFTTNQGDCPLIVQ 87 Query: 81 FAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140 FAAN+ DA+++V PY +G+D+NCGCPQ+WAM +GYG L++KPE++ D+VK +RN Sbjct: 88 FAANDARLLSDAARIVCPYANGIDINCGCPQRWAMAEGYGACLINKPELVQDMVKQVRNQ 147 Query: 141 LPNK-FSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSGPVDINGLKEVRE 199 + FS+S+KIR+ +D+K+TV LCQ+ E GV+++T + PV + +K ++E Sbjct: 148 VETPGFSVSIKIRIHDDLKRTVDLCQKAEATGVSWITVHGRTAEERHQPVHYDSIKIIKE 207 Query: 200 ALSVPMVANGGVKHLNDA 217 +S+P++ANG ++ L +A Sbjct: 208 NMSIPVIANGDIRSLKEA 225 >UniRef50_Q9VJ06 Cluster: CG10495-PA; n=2; Sophophora|Rep: CG10495-PA - Drosophila melanogaster (Fruit fly) Length = 396 Score = 214 bits (522), Expect = 2e-54 Identities = 103/217 (47%), Positives = 146/217 (67%), Gaps = 7/217 (3%) Query: 6 DIMEKFADAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARA 65 DI FA+A+ + +++V APMVRYSK+ FR LVR L FTPM+++DS + KAR Sbjct: 11 DIAAMFAEAQSD--FVRVSAPMVRYSKLEFRRLVRLNGVQLAFTPMMISDSINNSEKARQ 68 Query: 66 NEFMTTTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLS 125 NEF T D P+IAQFAA + +FV +++L+YPYVDG+DLNCGCPQ WAM GYGC +L Sbjct: 69 NEFSTGADDQPLIAQFAAKDPTEFVTSAQLIYPYVDGIDLNCGCPQSWAMAKGYGCGMLR 128 Query: 126 KPEIIYDIVKGLRNVLPNKFSISVKIRLL---NDIKKTVILCQQLEKCGVTFLT--SMEE 180 +PE+++ +V+ +R LP FS+SVK+RLL +++T+ L +QLE GVTFLT Sbjct: 129 QPELVHQVVQEVRRTLPGDFSVSVKMRLLGGEESLQRTIDLARQLESAGVTFLTLHGRTP 188 Query: 181 HCTKSSGPVDINGLKEVREALSVPMVANGGVKHLNDA 217 S +DI + +VR++L +P++ NG V+ DA Sbjct: 189 AQKHSKDTLDIPAMSQVRQSLQIPLIVNGNVESYRDA 225 >UniRef50_Q54ES7 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 344 Score = 177 bits (431), Expect = 2e-43 Identities = 83/199 (41%), Positives = 133/199 (66%), Gaps = 3/199 (1%) Query: 20 YLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIA 79 ++K+ APMVR+S++ FR LV+ + D+ +TPMI+A F ++ AR ++F D P+I Sbjct: 55 FMKIQAPMVRFSRLPFRMLVKKWGCDITYTPMIMAAEFNRSEAARDSDFTINKLDEPLIV 114 Query: 80 QFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139 QF NN ++ V A++ V Y G+D+NCGCPQ+W MK+G+G +LL PE IYD+VK + N Sbjct: 115 QFGVNNAEELVSAAEKVKDYCQGIDINCGCPQRWVMKEGFGANLLLHPERIYDMVKQINN 174 Query: 140 VLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVR 198 +P IS+KIR+ +D+K T+ L ++ E+ GV+++T KSS PVD + +K V+ Sbjct: 175 RVP--IPISIKIRVQSDLKDTIELAKRAERIGVSWITVHGRTSAMKSSHPVDYDAIKLVK 232 Query: 199 EALSVPMVANGGVKHLNDA 217 + +++P+ ANG V L+ + Sbjct: 233 DNVTLPVFANGDVFTLSQS 251 >UniRef50_Q09504 Cluster: Uncharacterized tRNA-dihydrouridine synthase-like protein C45G9.2; n=2; Caenorhabditis|Rep: Uncharacterized tRNA-dihydrouridine synthase-like protein C45G9.2 - Caenorhabditis elegans Length = 284 Score = 174 bits (424), Expect = 1e-42 Identities = 85/192 (44%), Positives = 130/192 (67%), Gaps = 1/192 (0%) Query: 27 MVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAANNR 86 MVRYSK+ FR LVR ++ D+CFTPMI A +F ++ K R++E D P+I QFA ++ Sbjct: 1 MVRYSKLAFRQLVRVYDVDVCFTPMIYAKNFIESEKCRSSELSVCEGDSPLIVQFATDDP 60 Query: 87 DDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN-KF 145 +A+++VY GVDLNCGCP+ G+G +LLSKPE++ D+V+ R +P+ F Sbjct: 61 FVLSEAAEMVYKCSTGVDLNCGCPKHDVRSKGFGSALLSKPELLADMVRQTRARIPDPDF 120 Query: 146 SISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSGPVDINGLKEVREALSVPM 205 S+S+KIR+ +DI+KTV LC++ E GVT LT ++ + P+DI L+ V++++SVP+ Sbjct: 121 SVSLKIRINHDIEKTVDLCRKAEAAGVTHLTVHGRTPSQRAEPIDIQALRIVKDSVSVPI 180 Query: 206 VANGGVKHLNDA 217 +ANGG+ +A Sbjct: 181 IANGGITTREEA 192 >UniRef50_O74553 Cluster: tRNA dihydrouridine synthase Dus4; n=1; Schizosaccharomyces pombe|Rep: tRNA dihydrouridine synthase Dus4 - Schizosaccharomyces pombe (Fission yeast) Length = 326 Score = 170 bits (413), Expect = 3e-41 Identities = 85/206 (41%), Positives = 127/206 (61%), Gaps = 2/206 (0%) Query: 10 KFADAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFM 69 K + K + + APMVRYSK+ FR LVR++N D+ +TPMILA F + K R +F Sbjct: 10 KIFEINKGKRPVHIAAPMVRYSKLPFRQLVRDYNTDIVYTPMILAKEFL-HPKGRYFDFS 68 Query: 70 TTTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129 T D +I QF ++ A++LV PYVDG+ +NCGCPQ WA+++G G +LL +PE Sbjct: 69 TNDADASLILQFGVDDPVILEKAAQLVGPYVDGIGINCGCPQTWAIQEGIGSALLDEPEK 128 Query: 130 IYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGP 188 ++ +V+ +++ L F VKIR+ D+ KT L Q +EK G +T +SS P Sbjct: 129 VHKLVRAVKSTLGESFCTEVKIRIAKDLNKTRHLMQVIEKSGADIITVHGRTRQDRSSFP 188 Query: 189 VDINGLKEVREALSVPMVANGGVKHL 214 V+++ ++EVR + +P+VANG VK L Sbjct: 189 VNLDAIREVRPCVQIPVVANGDVKSL 214 >UniRef50_A7EMF2 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 342 Score = 154 bits (373), Expect = 2e-36 Identities = 82/213 (38%), Positives = 123/213 (57%), Gaps = 6/213 (2%) Query: 11 FADAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMT 70 F AK L CAPMVRYSK+ FR V + DLC+TPMILA F ++ AR ++F T Sbjct: 21 FDIAKQEGRPLYTCAPMVRYSKLAFRETVAQYGVDLCWTPMILAKEFNRSVFARDSDFTT 80 Query: 71 TTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEII 130 + T P IAQF + + ++ L+ PY++G+D+NCGCPQ WA G +L+ K E++ Sbjct: 81 SPTSTPTIAQFGVCSPLEISRSTTLIAPYINGIDINCGCPQSWACACSIGAALMHKRELV 140 Query: 131 YDIVKGLRNVL-----PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTK 184 ++VK ++ L K ++SVKIR+ D++ TV + ++ GV F+T T Sbjct: 141 AEMVKEAKSALKREGYEGKKTVSVKIRIHRDLRDTVDFIKTVQDAGVDFITIHGRMRSTP 200 Query: 185 SSGPVDINGLKEVREALSVPMVANGGVKHLNDA 217 SS PV++ +K + +VP V+NG + L A Sbjct: 201 SSHPVNLEAIKLLNTHTTVPTVSNGDITSLRSA 233 >UniRef50_Q5A4Y0 Cluster: Potential tRNA dihydrouridine synthase; n=2; Saccharomycetales|Rep: Potential tRNA dihydrouridine synthase - Candida albicans (Yeast) Length = 339 Score = 153 bits (371), Expect = 3e-36 Identities = 73/196 (37%), Positives = 121/196 (61%), Gaps = 2/196 (1%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 + PMVRYSK+ FR L R ++ D+ +TPMILA F +N AR+ +F T +D VI Q Sbjct: 29 IAGPMVRYSKLPFRELCRFYDVDIVYTPMILAREFVRNEVARSTDFTTNDSDKCVIVQVG 88 Query: 83 ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 NN DDF+ ++++P+VDG+ +NCGCP K +++G G +L+S P+++ +++K ++ Sbjct: 89 VNNVDDFMKFIEMIHPFVDGIGINCGCPIKEQVREGIGAALMSDPDLVAELIKTAKDKYG 148 Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE-A 200 + I KIR+ DI +T+ ++ + G LT T+SS PV+++ +K +RE Sbjct: 149 DSICIDTKIRIHRDINQTIDFVNKVVEAGTDTLTVHGRTKNTRSSVPVNLDAIKIIRENV 208 Query: 201 LSVPMVANGGVKHLND 216 ++P++ANG L D Sbjct: 209 TTIPVIANGDCFTLTD 224 >UniRef50_Q06063 Cluster: tRNA-dihydrouridine synthase 4; n=10; Saccharomycetales|Rep: tRNA-dihydrouridine synthase 4 - Saccharomyces cerevisiae (Baker's yeast) Length = 367 Score = 146 bits (354), Expect = 4e-34 Identities = 72/198 (36%), Positives = 118/198 (59%), Gaps = 4/198 (2%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 + PMVRYSK+ FR L R +N D+ ++PMILA + +N AR ++ T D P+I Q Sbjct: 42 IAGPMVRYSKLPFRQLCREYNVDIVYSPMILAREYVRNEHARISDLSTNNEDTPLIVQVG 101 Query: 83 ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 NN D + ++V PY DG+ +NCGCP K +++G GC+L+ +++ +V +++ Sbjct: 102 VNNVADLLKFVEMVAPYCDGIGINCGCPIKEQIREGIGCALIYNSDLLCSMVHAVKDKYG 161 Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREAL 201 +K I KIR+ + +TV LC++L GV ++T T+SS P +++ +K + E + Sbjct: 162 DKLRIETKIRIHEALDETVELCRKLCDAGVDWITIHGRTRRTRSSQPANLDAIKYIIENI 221 Query: 202 S---VPMVANGGVKHLND 216 S VP++ANG L+D Sbjct: 222 SDKNVPVIANGDCFKLSD 239 >UniRef50_Q583Y8 Cluster: TRNA-dihydrouridine synthase 4, putative; n=3; Trypanosoma|Rep: TRNA-dihydrouridine synthase 4, putative - Trypanosoma brucei Length = 419 Score = 145 bits (351), Expect = 9e-34 Identities = 79/210 (37%), Positives = 124/210 (59%), Gaps = 8/210 (3%) Query: 10 KFADAKINKTY---LKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARAN 66 ++A ++ K Y LK+ APMVR S+ FR L R + D+ +T MI+ADSF + AR Sbjct: 46 EWACQRMEKAYGSILKIQAPMVRCSRPAFRKLCRLWGTDISYTHMIMADSFACSEAARQA 105 Query: 67 EFMTTTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSK 126 EF + + +I Q A+++ A+ +V P+ D +DLNCGCPQ+ M DG G +LL Sbjct: 106 EFSIYSGETRLITQLASSSGPTAATAAAIVAPWCDAIDLNCGCPQRRVMADGLGAALLRN 165 Query: 127 PEIIYDIVKGLRNVLPNKFSIS--VKIRLLNDIKKTVILCQQLEKCGVTFLT--SMEEHC 182 PE++ D V+ +RN L + VK+R+ +D++ +V +Q E G ++T +C Sbjct: 166 PEVVADTVRCVRNALEGGVELPCVVKMRVKDDVRLSVDFARQCEAAGAAWITVHGRTPNC 225 Query: 183 TKSSGPVDINGLKEVREALSVPMVANGGVK 212 + + PV + + +REAL VP+VANGGV+ Sbjct: 226 S-AHAPVRFDAINTIREALGVPVVANGGVR 254 >UniRef50_Q4Q391 Cluster: Putative uncharacterized protein; n=3; Leishmania|Rep: Putative uncharacterized protein - Leishmania major Length = 493 Score = 134 bits (325), Expect = 1e-30 Identities = 82/225 (36%), Positives = 127/225 (56%), Gaps = 27/225 (12%) Query: 20 YLKVC---APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP 76 Y +C APMVR S+ FR + R + + +T M++A+SF ++ AR EF + Sbjct: 93 YCSLCLIQAPMVRCSRPAFRQVCRAWGTRVSYTHMLMAESFVKSPHARHAEFARYEGENR 152 Query: 77 VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136 ++AQ AA + A+ L+ PY DG+DLNCGCPQ+WAMK+G G +LL +PE + D+V+ Sbjct: 153 LVAQLAAKSGPAAAQAALLLRPYCDGIDLNCGCPQRWAMKEGIGAALLDQPERVADMVRS 212 Query: 137 LRNVLPN------------KFS-----------ISVKIRLLNDIKKTVILCQQLEKCGVT 173 +RN +P+ ++S VK+R+ +D++++V +Q E GV+ Sbjct: 213 IRNAMPDGSTAPMIVGNGGEYSSCTSAVPPFLPCVVKMRIKDDLRRSVDFARQCEAAGVS 272 Query: 174 FLTSMEEHCT-KSSGPVDINGLKEVREALSVPMVANGGVKHLNDA 217 +LT T SS V +K +RE LSVP+V NGGV ++ A Sbjct: 273 WLTVHGRTPTCHSSTAVQFEAVKLIRENLSVPVVLNGGVTDVSTA 317 >UniRef50_A5K1E0 Cluster: tRNA-dihydrouridine synthase, putative; n=5; Plasmodium|Rep: tRNA-dihydrouridine synthase, putative - Plasmodium vivax Length = 340 Score = 128 bits (310), Expect = 8e-29 Identities = 74/199 (37%), Positives = 112/199 (56%), Gaps = 8/199 (4%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 + APMV S++ FR L RN+N L FTPM+ A +F ++ K R + F + D PVIAQF Sbjct: 29 ILAPMVDLSELAFRLLCRNYNCHLTFTPMLHAKNFVEHEKYRKSYFQSCEKDEPVIAQFC 88 Query: 83 ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 NN ++A + + V+ VDLN GCPQ+ A K YG LL K + + ++V + N Sbjct: 89 GNNSKIILNAIEYIKNEVNAVDLNLGCPQQIAKKGNYGAFLLQKHDEVVNLVSDITNNC- 147 Query: 143 NKFSISVKIRLLN-DIKKTVILCQQLEKCGVTFLT----SMEEHCTKSSGPVDINGLKEV 197 I+ KIR ++ D +KT+ LC L+ V +T + EE T D +K + Sbjct: 148 -NIPITCKIRKIDQDYQKTLNLCYDLQSRNVKMITVHGRTKEEKGTNIK-QCDYEIIKII 205 Query: 198 REALSVPMVANGGVKHLND 216 +E L++P++ANG ++H D Sbjct: 206 KERLNIPIIANGSIEHFED 224 >UniRef50_Q54XQ6 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 435 Score = 127 bits (307), Expect = 2e-28 Identities = 73/202 (36%), Positives = 109/202 (53%), Gaps = 5/202 (2%) Query: 18 KTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPV 77 K+ K APMV ++ + FR L R + AD+ +TPM + +F R + + T D P+ Sbjct: 50 KSPKKTVAPMVDHTFLAFRMLCRKYGADMVYTPMFHSKNFATCKTYRRDYWSTCPEDRPL 109 Query: 78 IAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGL 137 + QF N + V A+K + + D +DLN GCPQ+ A + YG LL KP II IV+ L Sbjct: 110 VVQFCGNEPEWVVKAAKYIEDHCDAIDLNLGCPQQIARRGNYGSFLLDKPHIILPIVQEL 169 Query: 138 RNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVDINGL 194 + K I KIRLL ++ T+ L QL++ G LT +E +SG + + Sbjct: 170 HKHI--KVPIFCKIRLLPNLDDTIKLALQLQEAGCQLLTIHGRTKEQKGHNSGIANWKAI 227 Query: 195 KEVREALSVPMVANGGVKHLND 216 + +RE LS+P++ANG V D Sbjct: 228 RTIREQLSIPVIANGSVVQYED 249 >UniRef50_Q9FH91 Cluster: Gb|AAF51525.1; n=6; Magnoliophyta|Rep: Gb|AAF51525.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 423 Score = 123 bits (297), Expect = 3e-27 Identities = 67/203 (33%), Positives = 108/203 (53%), Gaps = 5/203 (2%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 + APMV S++ FR L + + A +TPM+ + F + K R EF T D P+ QF Sbjct: 91 IVAPMVDNSELPFRLLCQKYGAQAAYTPMLHSRIFTETEKYRNQEFTTCKEDRPLFVQFC 150 Query: 83 ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 AN+ D ++A+K V PY D VD+N GCPQ+ A + YG L+ ++ +V+ L L Sbjct: 151 ANDPDTLLEAAKRVEPYCDYVDINLGCPQRIARRGNYGAFLMDNLPLVKSLVEKLAQNL- 209 Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSGP---VDINGLKEVRE 199 +S KIR+ +++ T+ + LE G + L + G D + +KEV+ Sbjct: 210 -NVPVSCKIRIFPNLEDTLKYAKMLEDAGCSLLAVHGRTRDEKDGKKFRADWSAIKEVKN 268 Query: 200 ALSVPMVANGGVKHLNDATTYMK 222 A+ +P++ANG V+ + D +K Sbjct: 269 AMRIPVLANGNVRCIEDVDNCIK 291 >UniRef50_Q9VPM1 Cluster: CG3645-PA, isoform A; n=2; Diptera|Rep: CG3645-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 505 Score = 123 bits (297), Expect = 3e-27 Identities = 69/197 (35%), Positives = 106/197 (53%), Gaps = 5/197 (2%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 V APMV S++ +R L R + A+LC++PM A+ F + K R + T D P+I QF Sbjct: 31 VVAPMVDQSELAWRMLCRRYGAELCYSPMYHANLFATDPKYRKDALQTCPEDRPLIIQFC 90 Query: 83 ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 N+ +DA+ L + D VD+N GCPQ A + YG L + E++ +IV L L Sbjct: 91 GNDAQQILDAALLAQDHCDAVDINLGCPQAIAKRGHYGSFLQDEWELLTEIVSTLHAKL- 149 Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVDINGLKEVRE 199 ++ KIR+ D++KT+ + LE G LT E +G + N +K VR+ Sbjct: 150 -AVPVTCKIRIFEDLEKTIRYAKMLEAAGCQLLTVHGRTREQKGPLTGVANWNYIKNVRQ 208 Query: 200 ALSVPMVANGGVKHLND 216 + +PM+ANG + L+D Sbjct: 209 HIKIPMLANGNILALDD 225 >UniRef50_A7AQM0 Cluster: Dihydrouridine synthase, putative; n=1; Babesia bovis|Rep: Dihydrouridine synthase, putative - Babesia bovis Length = 355 Score = 122 bits (295), Expect = 5e-27 Identities = 68/199 (34%), Positives = 109/199 (54%), Gaps = 7/199 (3%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 V APMV S++ FR L R +N DL +TPM+ F +N K RA F T+ D P+IAQ Sbjct: 15 VAAPMVNQSELPFRLLCRRYNVDLTYTPMLHGRIFVENEKYRAVHFQTSDDDRPLIAQVC 74 Query: 83 ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 ++ A++L+ +V VDLN GCPQ A YG LL +P+++ IV + + Sbjct: 75 GDDAGTITQAARLLKGHVSAVDLNLGCPQAIAKDGHYGSFLLDEPDLVTGIVSRVTREV- 133 Query: 143 NKFSISVKIRLL--NDIKKTVILCQQLEKCGVTFLTSMEEHCTKSS---GPVDINGLKEV 197 +++ KIR + + ++ T+ LC LE+ G LT H ++ G D + ++ + Sbjct: 134 -GIAVTCKIRKVDKDSLQSTLNLCYSLEQSGCKALTVHGRHRSEKGTNVGAADWDAIRII 192 Query: 198 REALSVPMVANGGVKHLND 216 + L +P++ANGG++ D Sbjct: 193 KSRLRIPVIANGGIETFAD 211 >UniRef50_Q9XVN8 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 527 Score = 122 bits (293), Expect = 9e-27 Identities = 75/211 (35%), Positives = 111/211 (52%), Gaps = 7/211 (3%) Query: 17 NKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP 76 N+ KV APMV S++ FR R + A L FTPMI A F + R N D P Sbjct: 70 NQRITKVLAPMVDQSELAFRMFTRKYGAQLTFTPMIHAHLFVNDGTYRRNSLALVKADRP 129 Query: 77 VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136 ++ QF AN D F+ A +LV DGVDLN GCPQ A + YG L + ++I ++V Sbjct: 130 LVVQFCANKVDTFLAACRLVEDVCDGVDLNLGCPQMVAKRGRYGSWLQDEVDLICEMVSA 189 Query: 137 LRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVDING 193 +R+ + IS KIR+ +D ++TV ++L G T LT + +G D + Sbjct: 190 VRDYC--RLPISCKIRVRDDRQQTVEYAKRLVDAGATMLTVHGRTRDMKGAETGLADWSR 247 Query: 194 LKEVREALS--VPMVANGGVKHLNDATTYMK 222 +++V EA+ VP++ANG ++ D M+ Sbjct: 248 IRDVVEAVGSRVPVMANGNIQFPGDVERCMQ 278 >UniRef50_Q5KPM6 Cluster: Putative uncharacterized protein; n=2; Filobasidiella neoformans|Rep: Putative uncharacterized protein - Cryptococcus neoformans (Filobasidiella neoformans) Length = 407 Score = 121 bits (292), Expect = 1e-26 Identities = 61/145 (42%), Positives = 94/145 (64%), Gaps = 5/145 (3%) Query: 77 VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136 +IAQFA+ N DA++L+ PYVDG+DLNCGCPQ+WA +G GC+LL KPE++ D+V+G Sbjct: 152 LIAQFASPNAKSLADAAELISPYVDGIDLNCGCPQRWAYNEGIGCALLRKPELVRDMVRG 211 Query: 137 LRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT--SMEEHCTKSSGPVDINGL 194 +++ + + +S+KIR+ ++ +KT L + G++ LT H S+ PV++ G+ Sbjct: 212 VKDRMGWGWPVSIKIRIDSEQEKTEQLISNALQAGISHLTIHGRTRH-QPSTDPVNLPGI 270 Query: 195 KEVREAL--SVPMVANGGVKHLNDA 217 K + + VP VANG V L DA Sbjct: 271 KFAVDCVKGEVPCVANGDVWELEDA 295 Score = 44.4 bits (100), Expect = 0.002 Identities = 21/52 (40%), Positives = 32/52 (61%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTD 74 V AP+VR SK+ FR L + + TPMILA+ F + AR ++F T++ + Sbjct: 35 VLAPLVRCSKLPFRHLTSLYETHITHTPMILAEEFSRAQIARTSDFSTSSNE 86 >UniRef50_A4S141 Cluster: Predicted protein; n=1; Ostreococcus lucimarinus CCE9901|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 307 Score = 121 bits (291), Expect = 2e-26 Identities = 65/197 (32%), Positives = 113/197 (57%), Gaps = 7/197 (3%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 APMV S++ FR L + + A L +TPMI A F ++ K R F T+T D P++AQF AN Sbjct: 21 APMVDQSELAFRELCKRYGATLGYTPMIHARLFVESPKYRREIFSTSTRDRPLLAQFCAN 80 Query: 85 NRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNK 144 + + + A+ ++ PY DGVD+N GCPQ+ A + YG L+ + + +++ L LP Sbjct: 81 DPEILLRAATMIAPYCDGVDINFGCPQRIAKRGNYGAFLMDDWKTVEALIRKLDEELP-- 138 Query: 145 FSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSGPVDING----LKEVREA 200 ++ KIR+ +D++ T+ + +E G + ++ + DI ++ +++A Sbjct: 139 VPVTAKIRVYDDLETTLKYAKMVEAAGAQ-IVAVHGRTREQKRCADIRANWAYIRAIKDA 197 Query: 201 LSVPMVANGGVKHLNDA 217 L VP++ANG ++ L +A Sbjct: 198 LKVPVLANGDIRSLAEA 214 >UniRef50_Q5CSA9 Cluster: Dus1p, tRNA dihydrouridine synthase; n=2; Cryptosporidium|Rep: Dus1p, tRNA dihydrouridine synthase - Cryptosporidium parvum Iowa II Length = 409 Score = 117 bits (282), Expect = 2e-25 Identities = 67/199 (33%), Positives = 105/199 (52%), Gaps = 6/199 (3%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 V APMV S++ FR + + + DL ++PM + F + R F T D P+I QF Sbjct: 22 VLAPMVDGSELAFRLICKKYGCDLGYSPMYHSGLFSKLQGYRETNFQTCEEDDPMIVQFC 81 Query: 83 ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 N+ + V ASK + V G+D+N GCPQ A + YG LLS P+++ I+ L + Sbjct: 82 GNDPETLVKASKFIDDKVKGIDINFGCPQNIAKRGNYGAFLLSNPDLMERIISTL-SESD 140 Query: 143 NKFSISVKIRLL--NDIKKTVILCQQLEKCGVTFLTSMEEHCTKS---SGPVDINGLKEV 197 K +S KIR+L +D++ T+ L ++LE G + T +GP + LK + Sbjct: 141 LKCPVSCKIRILDHHDLQPTINLIKRLESAGACMIAVHGRTMTSRGVLTGPANWEALKIL 200 Query: 198 REALSVPMVANGGVKHLND 216 + S+P +ANGG+ + D Sbjct: 201 KSRCSIPFIANGGISNYED 219 >UniRef50_Q6P1R4 Cluster: tRNA-dihydrouridine synthase 1-like; n=20; Euteleostomi|Rep: tRNA-dihydrouridine synthase 1-like - Homo sapiens (Human) Length = 473 Score = 115 bits (277), Expect = 8e-25 Identities = 73/201 (36%), Positives = 106/201 (52%), Gaps = 11/201 (5%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTT--DFPVIAQ 80 V APMV S++ +R L R A LC+TPM+ A F +++ R D P+I Q Sbjct: 20 VVAPMVDQSELAWRLLSRRHGAQLCYTPMLHAQVFVRDANYRKENLYCEVCPEDRPLIVQ 79 Query: 81 FAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140 F AN+ + FV A+ L Y D +DLN GCPQ A + YG L + +D+++ + + Sbjct: 80 FCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQDE----WDLLQRMILL 135 Query: 141 LPNKFSISV--KIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVDINGLK 195 K S+ V KIR+ +I KTV Q LEK G LT +E SG +K Sbjct: 136 AHEKLSVPVTCKIRVFPEIDKTVRYAQMLEKAGCQLLTVHGRTKEQKGPLSGAASWEHIK 195 Query: 196 EVREALSVPMVANGGVKHLND 216 VR+A+++P+ ANG ++ L D Sbjct: 196 AVRKAVAIPVFANGNIQCLQD 216 >UniRef50_A0EG06 Cluster: Chromosome undetermined scaffold_94, whole genome shotgun sequence; n=4; Intramacronucleata|Rep: Chromosome undetermined scaffold_94, whole genome shotgun sequence - Paramecium tetraurelia Length = 360 Score = 112 bits (269), Expect = 8e-24 Identities = 66/198 (33%), Positives = 104/198 (52%), Gaps = 7/198 (3%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTT-DFPVIAQF 81 +CAPMV S++ FR L R + L +TPM L SK+ +EF TT D P+ AQ Sbjct: 21 ICAPMVDQSELAFRMLTRKYGTTLAYTPM-LHSRIMTESKSYKDEFFTTCPEDRPLFAQL 79 Query: 82 AANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141 ++ + A+ ++ D +D+N GCPQ A K YG LL K E + IVK L+ + Sbjct: 80 CGHDPQVLIKAALMIQDQCDAIDINLGCPQGIARKGLYGAYLLEKREQVLTIVKELKQNI 139 Query: 142 PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVDINGLKEVR 198 ++ KIR+ D K+T+ L + +++ G + LT +E G D + E++ Sbjct: 140 --NVPVTCKIRMFKDRKRTLDLTKDIQEAGCSILTVHGRTKEQNKDFVGQCDWTIIAEIK 197 Query: 199 EALSVPMVANGGVKHLND 216 + L +P+ ANGG+ +D Sbjct: 198 QILQIPVFANGGIYTWSD 215 >UniRef50_A2FU21 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 322 Score = 110 bits (265), Expect = 2e-23 Identities = 60/209 (28%), Positives = 114/209 (54%), Gaps = 10/209 (4%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 V AP + + FR LVR +N LC+T M+ + + +R + F T + D P+I Q + Sbjct: 19 VLAPQFEVNDLAFRMLVRKYNVKLCWTGMVNSHMWAIQPSSRNSYFQTCSQDRPLIIQMS 78 Query: 83 ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 N+ + + +K + + G+D+NCGC Q A + YG +++ ++++ ++N++ Sbjct: 79 GNDESELIACAKDLQQFAVGIDINCGCTQHIARRGQYGYFMVNNENKRKNVIEMVKNIVA 138 Query: 143 N-KFSISVKIRLLN------DIKKTVILCQQLEKCGVTFLTSMEEHCTKS--SGPVDING 193 + +S+K RL++ D+ T ++LE GV+ L S+ S +GPVD Sbjct: 139 SINVPLSIKFRLIDGEDGKPDVDITCKFAKELEDAGVS-LISVHGRAKNSNKAGPVDAEA 197 Query: 194 LKEVREALSVPMVANGGVKHLNDATTYMK 222 ++++ E++S+P++ANGGV+ +A K Sbjct: 198 IRKIAESVSIPVMANGGVRTKEEAIEMFK 226 >UniRef50_UPI000023CFE7 Cluster: hypothetical protein FG01258.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG01258.1 - Gibberella zeae PH-1 Length = 362 Score = 105 bits (252), Expect = 9e-22 Identities = 57/133 (42%), Positives = 75/133 (56%), Gaps = 2/133 (1%) Query: 11 FADAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANE--F 68 F A+ +L APMVRY K+ FR V + DLC++PMILA F ++S AR ++ F Sbjct: 16 FDIARKQDRFLYALAPMVRYGKLAFRQTVHKYGVDLCWSPMILAKEFNRSSFARDSDWSF 75 Query: 69 MTTTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPE 128 T P I QF AN + AS LV P GVDLNCGCPQ WA + G +L++ E Sbjct: 76 STEPKQPPTIVQFGANVPLELARASALVAPSSQGVDLNCGCPQSWACAETLGAALMNHRE 135 Query: 129 IIYDIVKGLRNVL 141 ++ D+V R L Sbjct: 136 LVRDMVVETRQRL 148 >UniRef50_Q4UGK9 Cluster: Putative uncharacterized protein; n=2; Theileria|Rep: Putative uncharacterized protein - Theileria annulata Length = 359 Score = 104 bits (249), Expect = 2e-21 Identities = 66/195 (33%), Positives = 101/195 (51%), Gaps = 11/195 (5%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 + APMV S++ FR L R ++ADL +TPM+ A F +N R F T++ D P+IAQF Sbjct: 29 IVAPMVDQSELPFRLLCRRYSADLAYTPMLHAKIFSENENYRNIHFHTSSDDKPLIAQFC 88 Query: 83 ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 N+ F+ AS + V +D+N GCPQ A K YG LL P++ I KG +V Sbjct: 89 GNDPSAFILASSYIKNDVSAIDINLGCPQGIAKKGRYGSFLLEYPQL---ITKGFASV-D 144 Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSS-GPVDINGLKEVREAL 201 KF + + L +V C Q C + TK+ D + +K ++ + Sbjct: 145 TKFMLFTRGWLF-----SVQSC-QANGCKALTVHGRHRSETKTRISECDWDSIKIIKSRV 198 Query: 202 SVPMVANGGVKHLND 216 ++P++ANGG++ D Sbjct: 199 NIPVIANGGIETFED 213 >UniRef50_P53759 Cluster: tRNA-dihydrouridine synthase 1; n=11; Saccharomycetales|Rep: tRNA-dihydrouridine synthase 1 - Saccharomyces cerevisiae (Baker's yeast) Length = 423 Score = 103 bits (247), Expect = 4e-21 Identities = 65/209 (31%), Positives = 113/209 (54%), Gaps = 10/209 (4%) Query: 22 KVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMT---TTTDFPVI 78 ++ APMV S++ +R L R + A L +TPM+ A F + K R + + + ++ D P++ Sbjct: 31 RIVAPMVDQSELAWRILSRRYGATLAYTPMLHAKLFATSKKYREDNWSSLDGSSVDRPLV 90 Query: 79 AQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLR 138 QF AN+ + + A+KLV D VDLN GCPQ A K YG L+ + ++I++++ L Sbjct: 91 VQFCANDPEYLLAAAKLVEDKCDAVDLNLGCPQGIAKKGHYGSFLMEEWDLIHNLINTLH 150 Query: 139 NVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVDINGLK 195 L K ++ KIR+ +D +K++ + + G FLT + E + +G + +K Sbjct: 151 KNL--KVPVTAKIRIFDDCEKSLNYAKMVLDAGAQFLTVHGRVREQKGQKTGLANWETIK 208 Query: 196 EVREALSVPMV--ANGGVKHLNDATTYMK 222 +R+ L V ANG + + D + M+ Sbjct: 209 YLRDNLPKETVFFANGNILYPEDISRCME 237 >UniRef50_UPI0000499E32 Cluster: conserved hypothetical protein; n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved hypothetical protein - Entamoeba histolytica HM-1:IMSS Length = 339 Score = 101 bits (243), Expect = 1e-20 Identities = 60/197 (30%), Positives = 103/197 (52%), Gaps = 12/197 (6%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTT--DFPVIAQ 80 + APMV S + FR LVR +LC+TPM+L+ F + SK NE + + + P+I Q Sbjct: 25 ILAPMVDGSDLTFRILVRRHGVNLCYTPMVLSKMFVE-SKVYRNEVVNSLDPKEQPIIIQ 83 Query: 81 FAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140 ++ ++ +K + Y D +D+N GCPQK A K YG L + +D K + N Sbjct: 84 IVGSDANEMARTAKFLQSYCDAIDINLGCPQKIAQKGNYGAYL----ALDFDHTKEIVNA 139 Query: 141 LPNKFSISV--KIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSG---PVDINGLK 195 + +I V K+R+ D +KT+ + L++CG+ + T+ N + Sbjct: 140 VIEAVNIPVYCKVRVFEDEEKTMRFVEMLQECGIWGIAVHGRTITEKQSMNYHARWNYIA 199 Query: 196 EVREALSVPMVANGGVK 212 +++E L +P++ANG ++ Sbjct: 200 KIKERLKIPVIANGEMR 216 >UniRef50_Q9HGN6 Cluster: tRNA dihydrouridine synthase Dus1; n=1; Schizosaccharomyces pombe|Rep: tRNA dihydrouridine synthase Dus1 - Schizosaccharomyces pombe (Fission yeast) Length = 399 Score = 100 bits (239), Expect = 3e-20 Identities = 65/208 (31%), Positives = 102/208 (49%), Gaps = 9/208 (4%) Query: 22 KVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTT--DFPVIA 79 ++ APMV S++ +R L R ADLC++PM + F ++ R F T T + P+I Sbjct: 20 RILAPMVDQSELPWRILARRSGADLCYSPMFHSRLFGESEDYRNKVFSTRTIPEERPLII 79 Query: 80 QFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139 QF N+ + + A+K+ PY D VD+N GCPQ A K YG L +I I+ L Sbjct: 80 QFCGNDPEIMLKAAKIAAPYCDAVDVNLGCPQGIAKKGKYGSFLQENWNLIESIITKLHT 139 Query: 140 VLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVDINGLKE 196 L ++ KIR+ D +KT+ + + K G + L + E +G D ++ Sbjct: 140 EL--SIPVTAKIRIFPDPQKTLDYAKMILKAGASILAVHGRLREQKGHFTGIADWEQIQM 197 Query: 197 VREAL--SVPMVANGGVKHLNDATTYMK 222 +R+ L + ANG + H D +K Sbjct: 198 LRKNLPSETVLFANGNILHAQDIDRCIK 225 >UniRef50_A2EF32 Cluster: Dihydrouridine synthase, putative; n=1; Trichomonas vaginalis G3|Rep: Dihydrouridine synthase, putative - Trichomonas vaginalis G3 Length = 318 Score = 99.1 bits (236), Expect = 8e-20 Identities = 69/212 (32%), Positives = 108/212 (50%), Gaps = 13/212 (6%) Query: 23 VC-APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQF 81 +C APM S + +R L+RN +C+T M+ A + Q S + F T D P+IAQ Sbjct: 20 ICLAPMAEISDLSWRMLIRNHGVKVCWTGMLNAHQWSQGSGYQNKFFNTCPEDHPLIAQI 79 Query: 82 AANNRDD--FVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139 A +N D V A+K + Y DGVD+N GC QK A + YG ++ + ++ R Sbjct: 80 AGSNEDQDLIVAAAKDLAKYADGVDVNLGCTQKIASRSEYGYFMVDNCQKREKTLELFRR 139 Query: 140 VLPN-KFSISVKIRLLND------IKKTVILCQQLEKCGVTFLT--SMEEHCTKSSGPVD 190 + I KIR+ D K T+ ++LE+ GV+ L EH K + V Sbjct: 140 LCKEVNCPICAKIRIFIDDSGEVSEKITIDFAKKLEEAGVSLLQVHGRAEHRNKQA-DVY 198 Query: 191 INGLKEVREALSVPMVANGGVKHLNDATTYMK 222 +K + +A+++P+VANGG+ + DA +M+ Sbjct: 199 NEIIKHIVQAVNIPVVANGGINTVEDAHKFME 230 >UniRef50_Q8SUV4 Cluster: Putative uncharacterized protein ECU07_1610; n=1; Encephalitozoon cuniculi|Rep: Putative uncharacterized protein ECU07_1610 - Encephalitozoon cuniculi Length = 341 Score = 99.1 bits (236), Expect = 8e-20 Identities = 64/214 (29%), Positives = 113/214 (52%), Gaps = 9/214 (4%) Query: 8 MEKFADAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARA-N 66 M KF + +I + Y V APMV S+ +R L + A++ +T M+ DSF + S+ N Sbjct: 1 MRKFWE-EIQRPYFAV-APMVGNSEEAWRRLSKRHGANIFYTEMVHCDSFLRGSRNPVKN 58 Query: 67 EFMTTTT-DFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLS 125 + TT+ D P++ Q N+ + ++A+ ++ + D +D+N GCPQK A K GYG L Sbjct: 59 RWYTTSEGDRPLVVQICGNSPEVMLEAALIIQDHCDAIDVNFGCPQKVARKGGYGAYLQE 118 Query: 126 KPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHC 182 ++ +IVK L + L + KIR+ I+KTV + +E+ G + L + Sbjct: 119 NWKLTGEIVKVLSSGL--NVPVFCKIRVFGSIEKTVEYAKMIEEAGCSLLAVHGRTRDQR 176 Query: 183 TKSSGPVDINGLKEVREALSVPMVANGGVKHLND 216 + G ++ ++E L +P+++NG + +D Sbjct: 177 GAAMGFASWKHIRAIKENLRIPVLSNGNIMTHHD 210 >UniRef50_Q8PX79 Cluster: NifR3-like protein; n=5; Archaea|Rep: NifR3-like protein - Methanosarcina mazei (Methanosarcina frisia) Length = 323 Score = 98.3 bits (234), Expect = 1e-19 Identities = 64/209 (30%), Positives = 104/209 (49%), Gaps = 8/209 (3%) Query: 10 KFADAKINKTYLK---VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARAN 66 K KI +T L + APM + + FR L R + ADL +T MI D+ S+ Sbjct: 2 KLKKLKIGRTELSGNLLLAPMADVTNLAFRLLCRRYGADLTYTEMINVDALLNESRKSFI 61 Query: 67 EFMTTTTDFPVIAQFAANNRDDFVDASKLVYPYV--DGVDLNCGCPQKWAMKDGYGCSLL 124 + +++ D P Q D A+ + + +D+N GCP + G G +LL Sbjct: 62 KGLSSEEDRPFGVQLVGGCPDKLKRAALFIEEEYRPEIIDVNMGCPARCITGAGCGSALL 121 Query: 125 SKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTK 184 + PE++Y I+ L L +S KIRLL +KT+ + + +EK G + +T + Sbjct: 122 NSPELVYSIILELTESLDT--PVSAKIRLLGREEKTLEIARLIEKAGASAVTVHGRTAAQ 179 Query: 185 S-SGPVDINGLKEVREALSVPMVANGGVK 212 SG ++ G++ V+ LS+P++ANG VK Sbjct: 180 MYSGNSNLEGIRAVKNELSIPVIANGDVK 208 >UniRef50_A2DHB4 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 312 Score = 97.5 bits (232), Expect = 2e-19 Identities = 62/203 (30%), Positives = 103/203 (50%), Gaps = 10/203 (4%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP--VIAQFA 82 APM + FR L R LC+T I A + +K R + TT D ++ Q Sbjct: 18 APMADVNDYSFRKLCRQNGVSLCWTGFINAHHWVTRTKQRDRDVWFTTRDNEKNLVVQLL 77 Query: 83 ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 +N ++ V +K V + D ++LNCGC +A + G G L+ + + ++N++ Sbjct: 78 GSNLEELVSCAKDVENFCDMIELNCGCTHCFASRSGCGFFLIDTQKHRDSALILIQNLIK 137 Query: 143 N-KFSISVKIRLLND------IKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGL 194 + +S+KIRL++D +++TV Q LE+ GV+ +T G VD + + Sbjct: 138 SINKPVSIKIRLISDDNSVPSLERTVKFAQDLERVGVSLITVHARTQQADKKGDVDYDAI 197 Query: 195 KEVREALSVPMVANGGVKHLNDA 217 K V +A+SVP++ANGG+ L A Sbjct: 198 KAVVQAVSVPVIANGGISSLEQA 220 >UniRef50_Q00RI1 Cluster: OSIGBa0125M19.5 protein; n=9; Magnoliophyta|Rep: OSIGBa0125M19.5 protein - Oryza sativa (Rice) Length = 319 Score = 95.9 bits (228), Expect = 7e-19 Identities = 68/211 (32%), Positives = 106/211 (50%), Gaps = 19/211 (9%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSF--CQ---NSKARANEFMTTTTDFPV 77 V APMVR + FR L + AD+ + I+ F C+ N +F+ TD V Sbjct: 8 VLAPMVRVGTLPFRLLAAEYGADITYGEEIIDHKFLKCERVTNESLGTTDFLERGTDTVV 67 Query: 78 -----------IAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSK 126 + Q ++ + A++LV V +D+N GCP+ +++ G G +LLSK Sbjct: 68 FRTCPQERDRVVFQMGTSDAVRALKAAQLVCNDVAAIDINMGCPKSFSLSGGMGAALLSK 127 Query: 127 PEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHC-TKS 185 PE+I+DI+ LR L +++ KIRLLN + TV L +++EK GV L + Sbjct: 128 PELIHDILTTLRRNLDT--TVTCKIRLLNTRQDTVELARRVEKIGVPALAVHGRKVKDRP 185 Query: 186 SGPVDINGLKEVREALSVPMVANGGVKHLND 216 P + + +V ALS+P++ANG V D Sbjct: 186 RDPAKWDEIADVVSALSIPVIANGDVFEYED 216 >UniRef50_A6DCX2 Cluster: tRNA-dihydrouridine synthase B; n=1; Caminibacter mediatlanticus TB-2|Rep: tRNA-dihydrouridine synthase B - Caminibacter mediatlanticus TB-2 Length = 311 Score = 95.5 bits (227), Expect = 9e-19 Identities = 57/193 (29%), Positives = 104/193 (53%), Gaps = 9/193 (4%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 AP+ Y+ + FR++V+ F D+ F+ MI A++ N++ ++ + P Q AAN Sbjct: 16 APLAGYTDLPFRSVVKEFGCDMTFSEMINANAIAFNNEKTKKMMQKSSKETPYFIQIAAN 75 Query: 85 NRDDFVDASKLV--YPYVDGVDLNCGCPQKWAMKDGYGCSLL--SKPEIIYDIVKGLRNV 140 N ++ + A +++ P++DG+D+N GCP A + GYG LL E + +IV + + Sbjct: 76 NVENAIKAVEIINEIPWIDGIDINLGCPVNKARRSGYGGVLLKDENKEKLKEIVSAI--I 133 Query: 141 LPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS--SGPVDINGLKEVR 198 +K +S K+RL + V + LE G+ FLT + K G + +K+V Sbjct: 134 KTSKKIVSAKMRLGYNEVVAVDRAKMLEDLGIKFLT-VHGRTVKQMYKGNANYKEIKKVV 192 Query: 199 EALSVPMVANGGV 211 + +++P++ANG + Sbjct: 193 KEVNIPVIANGDI 205 >UniRef50_A4RU69 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 345 Score = 95.5 bits (227), Expect = 9e-19 Identities = 66/210 (31%), Positives = 106/210 (50%), Gaps = 16/210 (7%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSF--CQ---NSKARANEFMTT--TTDF 75 VCAPMVR S + R L + ADL + ++ F C+ N + + +F+ T F Sbjct: 16 VCAPMVRISTLATRLLAHEYGADLVYGEELVDKRFMHCRRILNKELGSVDFIDAKGTLTF 75 Query: 76 --------PVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKP 127 V+ Q ++ + +++LV V +D+N GCP+ ++ G G LLS+P Sbjct: 76 RTVPEERERVVFQVGTSSAASALKSAELVARDVAAIDVNMGCPKHFSTSGGMGARLLSQP 135 Query: 128 EIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVT-FLTSMEEHCTKSS 186 E++ DI+ LR LP+ ++ KIRLL ++T L + +E CGV+ F + Sbjct: 136 ELVRDILTTLRRNLPSTTHVTCKIRLLESERETAELAKMIESCGVSAFAVHGRYIPQRPR 195 Query: 187 GPVDINGLKEVREALSVPMVANGGVKHLND 216 P N +K V EA+ P++ANG V+ D Sbjct: 196 EPAHWNLIKNVVEAVDCPVIANGDVECYED 225 >UniRef50_Q4PBU9 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 477 Score = 95.1 bits (226), Expect = 1e-18 Identities = 47/120 (39%), Positives = 75/120 (62%), Gaps = 1/120 (0%) Query: 77 VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136 ++AQFA++ + F DAS+L+ +VDGVDLNCGCPQ WA ++ G LL +PE + D+V+ Sbjct: 169 LVAQFASSKPEPFADASELIGRFVDGVDLNCGCPQPWAYEELLGSYLLRQPETVRDMVRA 228 Query: 137 LRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFL-TSMEEHCTKSSGPVDINGLK 195 ++ + + F +SVKIR+ D++ T L + G + L SS PV+++G+K Sbjct: 229 VKARMGSDFCVSVKIRIDPDLRLTDALVRNALHAGASILQIHGRTRWQSSSEPVNLDGIK 288 Score = 59.3 bits (137), Expect = 7e-08 Identities = 28/50 (56%), Positives = 33/50 (66%) Query: 21 LKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMT 70 L VCAPMVRYSK+ FRTLV + + TPMILA F + AR +EF T Sbjct: 41 LNVCAPMVRYSKLAFRTLVSRYETHITTTPMILAKEFSRTEAARNSEFST 90 >UniRef50_Q57V78 Cluster: TRNA-dihydrouridine synthase 1, putative; n=1; Trypanosoma brucei|Rep: TRNA-dihydrouridine synthase 1, putative - Trypanosoma brucei Length = 520 Score = 91.5 bits (217), Expect = 2e-17 Identities = 68/230 (29%), Positives = 107/230 (46%), Gaps = 33/230 (14%) Query: 18 KTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTT----- 72 +T + V PMV S++ FR L R + A L +TPM A SF Q++ R F TTT Sbjct: 71 RTPMYVVGPMVDQSELPFRLLCRRYGATLAYTPMFHAKSFAQSAHYRQRYFSTTTFPPHS 130 Query: 73 ---------------------TDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQ 111 D P+ AQF N+ + + A++ V Y + VD N GCPQ Sbjct: 131 AMESGGNVAANDSTSNDGALDNDHPLFAQFCGNDPETVLAAARHVEDYCEAVDFNIGCPQ 190 Query: 112 KWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCG 171 A + YG L+ E++++I+ L L + ++ K+R+ +D T+ + L G Sbjct: 191 GIARRGHYGSFLMEDWELLHNILHALAVEL--RVPVTAKMRIFDDEALTLKYAEMLRDTG 248 Query: 172 VTFLT---SMEEHCTKSSGPVDINGLKEVREAL--SVPMVANGGVKHLND 216 + L E+ + P D+ ++ V E L S+P++ANG V D Sbjct: 249 IYVLCVHGRTRENKGQQQQPADLRMIRRVHEHLRGSIPIIANGNVLTFED 298 >UniRef50_UPI000023EA9A Cluster: hypothetical protein FG07217.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG07217.1 - Gibberella zeae PH-1 Length = 510 Score = 89.8 bits (213), Expect = 5e-17 Identities = 60/173 (34%), Positives = 86/173 (49%), Gaps = 21/173 (12%) Query: 23 VCAPMVRYSKVHFRTLVRNFNAD------LCFTPMILADSFCQNSKARANEFMTTTTDF- 75 + APMV S+ +R L R+F + L +TPM+ A F Q+ K R F TD Sbjct: 31 IVAPMVDQSEFAWRMLTRSFISPTEQKSLLAYTPMLHARLFSQDDKYRKAHFQAVKTDGE 90 Query: 76 ------------PVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSL 123 P+ QF AN+ D + A+K V PY D VDLN GCPQ A K YG L Sbjct: 91 TPWLDGNPSIDRPLFVQFCANDPDALLSAAKQVAPYCDAVDLNLGCPQGIARKGKYGAFL 150 Query: 124 LSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176 ++I+ ++ L LP ++ KIR+L+ ++T+ Q + K G + LT Sbjct: 151 QEDQDLIFRLINILHKELP--VPVTAKIRILDTKEETLAYAQNVLKAGASILT 201 >UniRef50_A6RW05 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 278 Score = 89.0 bits (211), Expect = 8e-17 Identities = 49/153 (32%), Positives = 83/153 (54%), Gaps = 6/153 (3%) Query: 66 NEFMTTTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLS 125 ++F T+ T P IAQF + + ++ L+ PYV+GVD+NCGCPQ WA G +L+ Sbjct: 26 DDFTTSPTSGPTIAQFGVCSPLEISRSTTLLAPYVNGVDINCGCPQSWACACSIGAALMH 85 Query: 126 KPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTK 184 K E++ ++VK ++ L K +++T+ ++ GV F+T T Sbjct: 86 KRELVAEMVKEAKSALKRDGFEGKK-----TVRETIDFINTVQDAGVDFITIHGRMRSTP 140 Query: 185 SSGPVDINGLKEVREALSVPMVANGGVKHLNDA 217 SS PV++ +K + +VP ++NG + L+DA Sbjct: 141 SSHPVNLEAIKLLTTHTTVPTLSNGDIFTLSDA 173 >UniRef50_Q6F288 Cluster: TRNA dihydrouridine synthetase; n=3; Mollicutes|Rep: TRNA dihydrouridine synthetase - Mesoplasma florum (Acholeplasma florum) Length = 325 Score = 88.6 bits (210), Expect = 1e-16 Identities = 57/193 (29%), Positives = 94/193 (48%), Gaps = 4/193 (2%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 V PM S FR + + ADL M+ + N+K + + P+ Q Sbjct: 13 VQGPMAGVSNPPFRLISKEKGADLVCAEMVSVEGMTHNNKKTFSMLAVEKKEHPMSMQIF 72 Query: 83 ANNRDDFVDASKLVYPYVDG--VDLNCGCPQ-KWAMKDGYGCSLLSKPEIIYDIVKGLRN 139 N+ + F+ A+K + VD +DLN GCP K A++ G SLL PE+IYDIVK + Sbjct: 73 GNDVESFIVATKWIDENVDCDIIDLNIGCPAPKVAVRSASGSSLLKTPELIYDIVKAVVE 132 Query: 140 VLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTK-SSGPVDINGLKEVR 198 + +++ + V + + +EK G + +T ++ SG D +KEV+ Sbjct: 133 NTSKPVTAKIRLGWDKESVNAVEVSKLIEKAGASGITVHGRTRSEFYSGHADWEKIKEVK 192 Query: 199 EALSVPMVANGGV 211 EA+++P++ NG V Sbjct: 193 EAVNIPVIGNGDV 205 >UniRef50_A2EN54 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 321 Score = 88.6 bits (210), Expect = 1e-16 Identities = 57/210 (27%), Positives = 106/210 (50%), Gaps = 11/210 (5%) Query: 23 VC-APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQF 81 VC APMV + FR L D+C+T MI + ++ R + + D P++ Q Sbjct: 15 VCLAPMVEMGDIAFRILCHRHGCDVCWTGMINGSQWNRSKTYRQQQIEYSEEDRPLVIQI 74 Query: 82 AANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141 + + D + +K + + +D+N GC QK A + YG ++ + ++V ++++ Sbjct: 75 SGSIDVDLLTTAKSMSEFGVPIDINLGCCQKVAKRGEYGYFMVDSEQKRQNVVNLIKSI- 133 Query: 142 PNKFSIS--VKIRLLND------IKKTVILCQQLEKCGVTFLTSMEEHCTKSS-GPVDIN 192 P++ ++ VKIR L D I TV + LE+ G + +T + GP++ Sbjct: 134 PSEITVPLYVKIRALTDESGIPSIPITVDFAKHLEEAGASLITIHGRSAAQDKHGPLNKE 193 Query: 193 GLKEVREALSVPMVANGGVKHLNDATTYMK 222 +K V +A+S+P++ NGG+ L+DA ++ Sbjct: 194 LVKAVVQAVSIPVIVNGGINSLDDARNMIR 223 >UniRef50_Q4PG83 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 527 Score = 87.8 bits (208), Expect = 2e-16 Identities = 68/230 (29%), Positives = 110/230 (47%), Gaps = 40/230 (17%) Query: 22 KVCAPMVRYSKVHFRTLVRNFNADLCFTPMI----LADSFCQNSKARANEF--------- 68 +V APMV S++ +R L R + +DL +TPMI AD + K + E Sbjct: 51 RVVAPMVDQSELAWRILSRRYGSDLVYTPMINAKLFADENSKKKKVKYQEVNFNREHAEE 110 Query: 69 ----------------MTTTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQK 112 + TD P+ QF +N+ + + A+K+V D VDLN GCPQ Sbjct: 111 GASSPIASLLSNEGEGSSKDTDRPLFVQFCSNDPETLLKAAKVVEDRCDAVDLNLGCPQH 170 Query: 113 WAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGV 172 A + YG L+ +I+ ++ L L K ++ K+R+ ++KT+ + LE+ G Sbjct: 171 IARRGHYGSYLMEDWSLIFSLINILHVNL--KVPVTAKMRVYESVEKTITYARLLERAGA 228 Query: 173 TFLT------SMEEHCTKSSGPVDINGLKEVREALSVPMVANGGVKHLND 216 +T +M+ H T G D ++ V+EA++VP+ ANG V + D Sbjct: 229 QIITVHGRTRNMKGHLT---GLADWAKIRAVKEAVNVPVFANGNVLYPQD 275 >UniRef50_A2F0D1 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 333 Score = 85.0 bits (201), Expect = 1e-15 Identities = 63/216 (29%), Positives = 100/216 (46%), Gaps = 23/216 (10%) Query: 26 PMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP--------- 76 PMVR S + FR + AD + P DS + + T +P Sbjct: 17 PMVRASNLPFRLMCLENGADGVYGPATSVDSILASHYDENEDPYTMYFGWPKNPHVHFHT 76 Query: 77 -------VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129 +I Q N+ V A+ +V + D +DLNCGCP+ +A G G SL+S+PEI Sbjct: 77 DPKEKGKLIFQILTNDASKAVQAASVVVKFADAIDLNCGCPESFATSRGTGSSLMSEPEI 136 Query: 130 IYDIVKGLRNVLPNKFSISVKIRLLNDIKKTV---ILCQQLEKCGVTFLTSMEEHCTKSS 186 + D+V LR ISVK R+ ++I++++ + C+ + ++E K+ Sbjct: 137 VADVVSALRR--NYNVPISVKHRIHHNIEESIQFAVACENAGASAIAVHGRLKEQ--KNK 192 Query: 187 GPVDINGLKEVREALSVPMVANGGVKHLNDATTYMK 222 G V + +K V + L V + NGGVK+ A M+ Sbjct: 193 GSVAYDNMKLVFDHLHVAKIGNGGVKNREMAKEMME 228 >UniRef50_A4M5I1 Cluster: Dihydrouridine synthase, DuS; n=1; Petrotoga mobilis SJ95|Rep: Dihydrouridine synthase, DuS - Petrotoga mobilis SJ95 Length = 301 Score = 84.2 bits (199), Expect = 2e-15 Identities = 52/198 (26%), Positives = 92/198 (46%), Gaps = 4/198 (2%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 APM Y+ FR + R F A FT MI DS + ++ + + + + + Q N Sbjct: 9 APMADYTDYPFREICRRFGAKFTFTEMISVDSIIRENE-KVEKMLPQKGEDNIGVQLFGN 67 Query: 85 NRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNK 144 F++A+K + +D+N CP +K G G +LL P+++ DIV L+ + Sbjct: 68 ETTKFIEAAKSIQHLASWIDINAACPVNKVVKKGSGAALLKNPKLLGDIVFNLKKSI--D 125 Query: 145 FSISVKIRLLNDIKKTVILCQQLEKCGVTF-LTSMEEHCTKSSGPVDINGLKEVREALSV 203 + VK+RL D + + +EK G + + SG + LK+++ +++ Sbjct: 126 LPVGVKVRLGYDQINIEEVAETVEKAGADYIIVHGRTRSQMYSGIANREILKKLKAKITI 185 Query: 204 PMVANGGVKHLNDATTYM 221 P+ A+G V D Y+ Sbjct: 186 PLGASGDVFSKKDIDDYL 203 >UniRef50_Q5KP54 Cluster: TRNA dihydrouridine synthase, putative; n=1; Filobasidiella neoformans|Rep: TRNA dihydrouridine synthase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 610 Score = 84.2 bits (199), Expect = 2e-15 Identities = 49/152 (32%), Positives = 79/152 (51%), Gaps = 5/152 (3%) Query: 74 DFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDI 133 D P+I QF AN+ D + A+K V D VD+N GCPQ A + YG L + E+I+ + Sbjct: 149 DRPLIVQFCANDPDILLAAAKKVEHRCDAVDINFGCPQGIAKRGHYGSFLQDEWELIHKL 208 Query: 134 VKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVD 190 + L L ++ K R+ D+ KT+ + +E G LT E +++G D Sbjct: 209 ISTLHENL--SVPVTAKFRIFPDLDKTIAYARMMEAAGAQILTCHGRTREMKGQNTGLAD 266 Query: 191 INGLKEVREALSVPMVANGGVKHLNDATTYMK 222 ++EV++A+ VP+ ANG + + D M+ Sbjct: 267 WEYIREVKKAVKVPVFANGNILYREDVDRCME 298 >UniRef50_Q9XWJ9 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 436 Score = 82.6 bits (195), Expect = 7e-15 Identities = 59/205 (28%), Positives = 106/205 (51%), Gaps = 20/205 (9%) Query: 22 KVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTT-----DFP 76 K+ APMVR + R L + ADLC+T I+ + ++ NE + T D Sbjct: 9 KILAPMVRAGRTPLRLLCLKYGADLCYTEEIVDKKLIEATRV-VNEALGTIDYRNGDDII 67 Query: 77 V----------IAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSK 126 + I Q N+ + +++V V G+D+N GCP+ +++ G G +LL++ Sbjct: 68 LRLAPEEKGRCILQIGTNSGEKAAKIAQIVGDDVAGIDVNMGCPKPFSIHCGMGAALLTQ 127 Query: 127 PEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFL-TSMEEHCTKS 185 E I DI+ L++ K ++ KIR+L+D + T+ L Q++EKC V+ L + Sbjct: 128 TEKIVDILTSLKSAA--KVPVTCKIRVLDDPEDTLKLVQEIEKCRVSALGVHGRRRDERQ 185 Query: 186 SGPVDINGLKEVREAL-SVPMVANG 209 I+ +++V +A+ S+P+++NG Sbjct: 186 PDKCRIDEIRDVAQAVQSIPVISNG 210 >UniRef50_A2ACC0 Cluster: Novel protein; n=17; Eumetazoa|Rep: Novel protein - Mus musculus (Mouse) Length = 194 Score = 82.2 bits (194), Expect = 9e-15 Identities = 59/188 (31%), Positives = 90/188 (47%), Gaps = 18/188 (9%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 V APMV S++ +R L R A LC+TPM+ A F +++ R + Sbjct: 20 VVAPMVDQSELAWRLLSRRHGAQLCYTPMLHAQVFVRDANYRKEN---------LYCDVC 70 Query: 83 ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 +R V A+ L Y D +DLN GCPQ A + YG L + +D+++ + + Sbjct: 71 PEDRPLIVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQEE----WDLLQRMILLAH 126 Query: 143 NKFSISV--KIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVDINGLKEV 197 + S+ V KIR+ +I KTV Q LEK G LT +E +G +K V Sbjct: 127 ERLSVPVTCKIRVFPEIDKTVRYAQMLEKAGCQLLTVHGRTKEQKGPMAGTASWEHIKAV 186 Query: 198 REALSVPM 205 R+A+ +P+ Sbjct: 187 RKAVGIPV 194 >UniRef50_Q4D174 Cluster: Dihydrouridine synthase (Dus), putative; n=2; Trypanosoma cruzi|Rep: Dihydrouridine synthase (Dus), putative - Trypanosoma cruzi Length = 548 Score = 81.8 bits (193), Expect = 1e-14 Identities = 66/230 (28%), Positives = 104/230 (45%), Gaps = 33/230 (14%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEF----------MTTT 72 V PMV S++ FR L R + A L ++PM+ A SF Q+++ RA F MT T Sbjct: 99 VVGPMVDQSELPFRMLCRRYGATLAYSPMLHARSFAQSAQYRARYFSTTPHRAELAMTAT 158 Query: 73 -------------------TDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKW 113 TD P+ QF N+ D + A++ V + VD+N GCPQ Sbjct: 159 ASGEGEAAEDAGRTSDGEETDHPLFVQFCGNDADTLLAAARHVEDDCEAVDVNLGCPQGI 218 Query: 114 AMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVT 173 A + YG L+ + +++I+ L L + ++ K+R+ +D T+ + L G+ Sbjct: 219 ARRGHYGSFLMEDWDRVHNILHCLAVEL--RVPVTAKMRVFDDDALTLKYAEMLRDTGIA 276 Query: 174 FLTSMEEHCTKSSGPVDINGLKEVREAL--SVPMVANGGVKHLNDATTYM 221 L G D+ ++ VRE L S+P++ NG V D M Sbjct: 277 VLCVHGRTRHNKRGIADMEKIRRVREHLRGSIPVIGNGNVLTFEDVRRNM 326 >UniRef50_Q7SGX4 Cluster: Putative uncharacterized protein NCU03195.1; n=1; Neurospora crassa|Rep: Putative uncharacterized protein NCU03195.1 - Neurospora crassa Length = 341 Score = 81.4 bits (192), Expect = 2e-14 Identities = 61/191 (31%), Positives = 90/191 (47%), Gaps = 24/191 (12%) Query: 49 TPMILADSFCQNSKARANEFMTTTT--DFPVIAQFAANNRDDFVDASKLVYPYVDGVDLN 106 TP QN AR ++ +T P + QF AN+ + AS LV PY GVDLN Sbjct: 4 TPERSNQDIVQNRFARDSDLTISTNGPQPPTVVQFGANDPQELARASTLVAPYAGGVDLN 63 Query: 107 CGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL---------------PNKFSISVKI 151 CGCPQ WA + G +L+ K E++ D+V R L P S+SVKI Sbjct: 64 CGCPQSWACAETLGAALMEKRELVRDMVIETREYLRRDGWGVGKERDVDNPKGRSVSVKI 123 Query: 152 RLLNDIKKTVILCQQL----EKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREAL--SVP 204 R+ D++KT+ + + + +LT T SS P+++ L+ + VP Sbjct: 124 RVHKDLRKTMDFITTVLGPSQDRHIDWLTIHPRTRQTPSSTPINVEALEILTSTFGDKVP 183 Query: 205 MVANGGVKHLN 215 ++ +G V LN Sbjct: 184 ILLSGDVFTLN 194 >UniRef50_Q6AJZ5 Cluster: TRNA-dihydrouridine synthase; n=1; Desulfotalea psychrophila|Rep: TRNA-dihydrouridine synthase - Desulfotalea psychrophila Length = 328 Score = 80.2 bits (189), Expect = 4e-14 Identities = 57/205 (27%), Positives = 89/205 (43%), Gaps = 10/205 (4%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 V AP+ Y+ + FR L F AD + MI N + + + PV Q Sbjct: 14 VLAPLAGYTDLSFRLLCHQFGADYTVSEMISCHGLFYNQQRTLEMLASLPEERPVSFQLF 73 Query: 83 ANNRDDFVDASKLVYPYV-DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141 D A+ ++ + D +D+N GCP + K G G +L+S PE+ YD++ R+V+ Sbjct: 74 GAEPDIMAKATLILNDFQPDMIDINMGCPVRKVTKKGAGAALMSTPELAYDVI---RSVV 130 Query: 142 PNKFSISVKIRLLNDIKKT----VILCQQLEKCGVTFL-TSMEEHCTKSSGPVDINGLKE 196 N I V ++ + T V E+ G + SG D +KE Sbjct: 131 DNT-DIPVTVKFRAGVSSTELNGVEFGLMTERAGAAAVAVHGRTRAQAFSGVADRGIIKE 189 Query: 197 VREALSVPMVANGGVKHLNDATTYM 221 V+EALS+P++ NG + D M Sbjct: 190 VKEALSIPVIGNGDILSYQDGLDMM 214 >UniRef50_Q4WRF0 Cluster: Dihydrouridine synthase family protein, putative; n=9; Pezizomycotina|Rep: Dihydrouridine synthase family protein, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 541 Score = 79.4 bits (187), Expect = 7e-14 Identities = 47/145 (32%), Positives = 74/145 (51%), Gaps = 5/145 (3%) Query: 74 DFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDI 133 D P+I QF AN+ DDF++A++ V PY D VDLN GCPQ A K YG L ++IY + Sbjct: 124 DRPLIVQFCANDPDDFLEAARHVAPYCDAVDLNLGCPQGIARKGHYGAFLQEDWDLIYKL 183 Query: 134 VKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVD 190 + L LP ++ K R+ +KT+ + + G + +T E ++G D Sbjct: 184 INRLHKELP--IPVTAKFRIQESKEKTLEYAKMILSAGASIITLHGRTREQKGHNTGLAD 241 Query: 191 INGLKEVREALSVPMVANGGVKHLN 215 + ++ +R+ L V +LN Sbjct: 242 WSYIRYLRDNLPPETVIFANGNNLN 266 >UniRef50_Q9NX74 Cluster: tRNA-dihydrouridine synthase 2-like; n=27; Eumetazoa|Rep: tRNA-dihydrouridine synthase 2-like - Homo sapiens (Human) Length = 493 Score = 79.0 bits (186), Expect = 9e-14 Identities = 56/206 (27%), Positives = 103/206 (50%), Gaps = 22/206 (10%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP------ 76 + APMVR + R L ++ AD+ + ++ Q K NE ++T DF Sbjct: 15 ILAPMVRVGTLPMRLLALDYGADIVYCEELIDLKMIQ-CKRVVNEVLSTV-DFVAPDDRV 72 Query: 77 -----------VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLS 125 V+ Q ++ + + ++LV V G+D+N GCP++++ K G G +LLS Sbjct: 73 VFRTCEREQNRVVFQMGTSDAERALAVARLVENDVAGIDVNMGCPKQYSTKGGMGAALLS 132 Query: 126 KPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFL-TSMEEHCTK 184 P+ I I+ L V + ++ KIR+L ++ T+ L +++E+ G+ + + + Sbjct: 133 DPDKIEKILSTL--VKGTRRPVTCKIRILPSLEDTLSLVKRIERTGIAAIAVHGRKREER 190 Query: 185 SSGPVDINGLKEVREALSVPMVANGG 210 PV +K + + LS+P++ANGG Sbjct: 191 PQHPVSCEVIKAIADTLSIPVIANGG 216 >UniRef50_A2FJB5 Cluster: TIM-barrel protein, nifR3 family protein; n=1; Trichomonas vaginalis G3|Rep: TIM-barrel protein, nifR3 family protein - Trichomonas vaginalis G3 Length = 301 Score = 78.6 bits (185), Expect = 1e-13 Identities = 54/196 (27%), Positives = 96/196 (48%), Gaps = 10/196 (5%) Query: 27 MVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAANNR 86 M Y+ + FR + AD+ T M+ A + +K + + + V Q ++ Sbjct: 1 MAGYTDIAFREVATEKGADITVTEMVSAMALVYENKKTIDLLDISPKEKKVAVQIFGSDP 60 Query: 87 DDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKF 145 D +A++++ Y VD+N GCP +K+ G LLS P ++YDIVK + V + Sbjct: 61 DVMGEAARILNDYDFSYVDINMGCPAPKIVKNNSGSHLLSNPSLVYDIVKSV--VKNSNK 118 Query: 146 SISVKIRLLNDIKKTVILCQQLEKCGVTFLT----SMEEHCTKSSGPVDINGLKEVREAL 201 ++ K+R ++ + +E G +F+T + EE+ T G D + +KEV+E + Sbjct: 119 PVTAKVRKGIGGVSSMKAIKNIEAAGASFVTVHGRTREEYYT---GKADWDFIKEVKENV 175 Query: 202 SVPMVANGGVKHLNDA 217 +P++ NG V DA Sbjct: 176 KIPVIGNGDVDSPEDA 191 >UniRef50_Q54QJ2 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 402 Score = 78.2 bits (184), Expect = 2e-13 Identities = 59/210 (28%), Positives = 106/210 (50%), Gaps = 24/210 (11%) Query: 22 KVCAPMVRYSKVHFRTLVRNFNADLCFTP-----MILADSFCQNSKARANEFM------- 69 K+ APMVR R L N+ D+ ++ ++ + N K + +F+ Sbjct: 34 KIMAPMVRVGTYPMRILAYNYGCDIAYSEELIDLKLMKSTRVVNEKLKTIDFIAKDQTLC 93 Query: 70 --TTTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKP 127 T+ D + Q + ++A+K+V + +D+N GCP+ ++++ G G +LLSKP Sbjct: 94 YRTSEKDVRNVLQLGTASSMTALEAAKVVCNDICALDINMGCPKFFSVQGGMGSALLSKP 153 Query: 128 EIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHC----T 183 E I DI+ L+ L N I+ KIRLL+ ++T+ L + +E GV +++ HC Sbjct: 154 ETIKDILTTLKRNL-NGIPITCKIRLLSTDQETIDLLRIIESTGV---SAIGVHCRMIPE 209 Query: 184 KSSGPVDINGLKEV--REALSVPMVANGGV 211 + P + L+ + + SVP++ANG + Sbjct: 210 RPRDPAHWDRLENILSNASFSVPIIANGDI 239 >UniRef50_Q5KGP0 Cluster: Putative uncharacterized protein; n=3; Filobasidiella neoformans|Rep: Putative uncharacterized protein - Cryptococcus neoformans (Filobasidiella neoformans) Length = 496 Score = 77.8 bits (183), Expect = 2e-13 Identities = 65/218 (29%), Positives = 107/218 (49%), Gaps = 26/218 (11%) Query: 13 DAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSF--CQNS--------- 61 D +IN V APMVR + R L + A L ++P ++ + + S Sbjct: 101 DNEINYKNKLVLAPMVRTGSLPMRLLSLYYGAGLVWSPEVVDRAIIGAERSVDPVTGVIT 160 Query: 62 --KARANEFMTTTTDFP-VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDG 118 K + F T + P +I Q ++N + V A++ V V G+DLNCGCP+ ++ G Sbjct: 161 YHKGQGPIFSTHPAEKPFLIFQIGSSNPELAVKAAQTVQQDVAGIDLNCGCPKPFSTHAG 220 Query: 119 YGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM 178 G +LLS PE++ DI++ L + +P IS KIRLL T+ L ++ + GV LT Sbjct: 221 MGAALLSTPELLLDILRALLDSIP--LPISCKIRLLPTQPSTLYLASRILRTGVRNLT-- 276 Query: 179 EEHC-TKSSGPVD------INGLKEVREALSVPMVANG 209 HC T+ P + ++ + E+ + + ++ NG Sbjct: 277 -VHCRTRQMRPGERALWERLSSIVELGKRRGISVICNG 313 >UniRef50_UPI00015B40A4 Cluster: PREDICTED: similar to tRNA-dihydrouridine synthase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to tRNA-dihydrouridine synthase - Nasonia vitripennis Length = 505 Score = 77.0 bits (181), Expect = 3e-13 Identities = 62/218 (28%), Positives = 103/218 (47%), Gaps = 21/218 (9%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTT-----TDFPV 77 + APMVR + R L + AD+ +T ++ D S R NE + T TD + Sbjct: 60 IMAPMVRIGTLPMRLLALEYGADIVYTEELI-DWKLLRSVRRVNEVLGTVDYIDRTDGTI 118 Query: 78 IAQFAANNRDDFV------DAS------KLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLS 125 + + + RD V DA+ KLV V G+D+N GCP+++++ G G +LL Sbjct: 119 VFRTSPIERDRVVLQLGTCDANRALKVAKLVEQDVAGIDVNMGCPKRFSILGGMGAALLK 178 Query: 126 KPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHC-TK 184 +PE +I++ L L ++ KIR+L +++ T+ L L G++ +T + Sbjct: 179 QPEKASEILRTLVGGL--SIPVTCKIRVLGNVEDTLKLVDTLVDTGISAITVHGRTVDER 236 Query: 185 SSGPVDINGLKEVREALSVPMVANGGVKHLNDATTYMK 222 P +K V E +P++ANGG K + K Sbjct: 237 PQHPNRSEFIKRVAEHAKIPVIANGGSKEIEKRADIFK 274 >UniRef50_Q7RX85 Cluster: Putative uncharacterized protein NCU00065.1; n=3; Pezizomycotina|Rep: Putative uncharacterized protein NCU00065.1 - Neurospora crassa Length = 629 Score = 77.0 bits (181), Expect = 3e-13 Identities = 70/224 (31%), Positives = 101/224 (45%), Gaps = 37/224 (16%) Query: 23 VCAPMVRYSKVHFRTLVRNF-NAD-----LCFTPMILADSFCQNSKARANEFMTT----T 72 + APMV S+ +R L R+F AD LC+TPM A F + K R + F T Sbjct: 53 IVAPMVDQSEFAWRMLTRSFLPADEQHKLLCYTPMFHARLFTEAPKYRDSHFQPIRGPLT 112 Query: 73 TDFP--------------------VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQK 112 D P + QF AN+ + A+KLV PY D VDLN GCPQ Sbjct: 113 ADSPRPDSSDYVPFLDGNPEFDRSLFVQFCANDPAYLLSAAKLVAPYCDAVDLNLGCPQG 172 Query: 113 WAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGV 172 A + YG L E+I++++ L L ++ KIR+L+ + T+ Q + + G Sbjct: 173 IAKRGQYGSFLQENQELIFELINTLHKEL--DIPVTAKIRILDTKEATLKYAQNVLRAGA 230 Query: 173 TFLT---SMEEHCTKSSGPVDINGLKEVREALSVPMV--ANGGV 211 + LT E +G D ++ +RE L V ANG + Sbjct: 231 SILTVHGRRREQKGHQTGLADWEYIRYLRENLPKETVIFANGNI 274 >UniRef50_Q59YG4 Cluster: Potential tRNA dihydrouridine synthase; n=2; Saccharomycetales|Rep: Potential tRNA dihydrouridine synthase - Candida albicans (Yeast) Length = 433 Score = 76.2 bits (179), Expect = 6e-13 Identities = 58/179 (32%), Positives = 91/179 (50%), Gaps = 24/179 (13%) Query: 22 KVC-APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTT--------- 71 K+C APMVR ++ R L + DL +TP ++ Q+++ E T Sbjct: 7 KLCLAPMVRSGELPIRLLSLRYGCDLLWTPELVDKKILQSTRIINQELNTIDYIVSNHQQ 66 Query: 72 ----TTDF---PV-----IAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGY 119 T F PV I Q +++ VDA++ V VDG+DLNCGCP+ ++ G Sbjct: 67 SDKKTVIFRKHPVETGRLILQLGSSDPQLAVDAARKVIDDVDGIDLNCGCPKNFSTHSGM 126 Query: 120 GCSLLSKPEIIYDIVKGL--RNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176 G LL P+ + I+ L + +PNK SIS KIRL N+ ++ L +++ + G++ LT Sbjct: 127 GAELLKTPDKLCSILINLVEKIGIPNKKSISCKIRLFNNYDQSKNLIEKILQTGISNLT 185 >UniRef50_Q1NXZ7 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3 precursor; n=2; delta proteobacterium MLMS-1|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 precursor - delta proteobacterium MLMS-1 Length = 313 Score = 75.4 bits (177), Expect = 1e-12 Identities = 53/203 (26%), Positives = 90/203 (44%), Gaps = 5/203 (2%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 V AP+ YS + FR L R + A LC++ M+ + A TT + P++ Q Sbjct: 16 VAAPLAGYSDLPFRLLCREYGAGLCYSEMLSCHGLVRRQPATIEMLATTAAERPLLMQLF 75 Query: 83 ANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141 + +A+ ++ +DG+D+N GCP + +K G G +L+ PE+ I G Sbjct: 76 GAEPEVMGEAAAILSRLPIDGIDINMGCPVRKVVKKGAGAALMRDPELAAAIT-GAVTAA 134 Query: 142 PNKFSISVKIRLLNDIKK--TVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVR 198 ++VKIR + K+ + L G +T + +G D + V+ Sbjct: 135 AGDLPVTVKIRSGWNHKQINAPDFARLLVAHGAAAVTIHARTWSDGFTGRADWAVIAAVK 194 Query: 199 EALSVPMVANGGVKHLNDATTYM 221 A+SVP++ NG + A M Sbjct: 195 RAVSVPVIGNGDIGSYEQALAMM 217 >UniRef50_Q8RFK3 Cluster: Nitrogen regulation protein NIFR3; n=3; Fusobacterium nucleatum|Rep: Nitrogen regulation protein NIFR3 - Fusobacterium nucleatum subsp. nucleatum Length = 307 Score = 74.5 bits (175), Expect = 2e-12 Identities = 52/196 (26%), Positives = 96/196 (48%), Gaps = 5/196 (2%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 AP+ + FR ++ +F DL FT M+ ++ + ++ + V Q Sbjct: 7 APIAGVTDYTFRGILEDFKPDLIFTEMVSVNALSVLNDKTISKILKLREGNAV--QIFGE 64 Query: 85 NRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143 + + + K + V ++LNCGCP K + GYG +L+ +PE I I+ +++VL N Sbjct: 65 DIEKIKASVKYIENLGVKHINLNCGCPMKKIVNCGYGAALVKEPEKIKKILSEIKSVLNN 124 Query: 144 KFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHCTK-SSGPVDINGLKEVREAL 201 +SVKIR+ + + + + + E+ G +T + SG D +KEV++ + Sbjct: 125 DTKLSVKIRIGYKEPENYIQIGKIAEELGCDHITVHGRTREQLYSGKADWKYIKEVKDNI 184 Query: 202 SVPMVANGGVKHLNDA 217 S+P++ NG + DA Sbjct: 185 SIPVIGNGDIFTGEDA 200 >UniRef50_Q2H6D9 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 464 Score = 74.5 bits (175), Expect = 2e-12 Identities = 54/175 (30%), Positives = 82/175 (46%), Gaps = 21/175 (12%) Query: 23 VCAPMVRYSKVHFRTLVRNFNAD------LCFTPMILADSFCQNSKARANEFMTTTTDF- 75 + APMV S+ +R L R+F + L ++PM A F ++ K R F T D Sbjct: 39 IVAPMVDQSEFAWRMLSRSFLPESEQSGLLAYSPMFHARLFSESQKYRDQHFQPTKPDCD 98 Query: 76 ------------PVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSL 123 P QF AN+ ++A+K+ PY D VDLN GCPQ A K YG L Sbjct: 99 KLYLDGNPAIDRPFFVQFCANDPQALLNAAKIAAPYCDAVDLNLGCPQGIAKKGHYGSFL 158 Query: 124 LSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM 178 ++I+ ++K L L ++ KIR+L + T+ Q + + + LT + Sbjct: 159 QEDQDLIHQLIKILHENL--DIPVTAKIRILETKEATLKYAQNVLRPTASILTCL 211 >UniRef50_Q8KB61 Cluster: TIM-barrel protein, nifR3 family; n=10; Chlorobiaceae|Rep: TIM-barrel protein, nifR3 family - Chlorobium tepidum Length = 352 Score = 73.7 bits (173), Expect = 3e-12 Identities = 50/197 (25%), Positives = 85/197 (43%), Gaps = 2/197 (1%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 + APM + FR L + AD+ +T I A++ + + + + PV Q Sbjct: 18 ILAPMEDVTDRAFRQLCKQHGADIVYTEFISAEALRRGVEKSIRKITVADHERPVAVQIF 77 Query: 83 ANNRDDFVDASKLVYPYV-DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141 N + V+A+ + Y D +D+N GCP K G G +LL +PE + +I + N + Sbjct: 78 GNTVESMVEAAAIAETYEPDYLDINFGCPVKKVAGRGAGAALLKEPEKLSEIASAVVNAV 137 Query: 142 PNKFSISVKIRLLNDIKKTVILCQQLEKCGV-TFLTSMEEHCTKSSGPVDINGLKEVREA 200 + +I +D ++LE G+ G D + E ++A Sbjct: 138 SLPVTAKTRIGWDHDSINITDTVRRLEDAGIRAVAVHGRTRSDMYKGRADWGRIAEAKQA 197 Query: 201 LSVPMVANGGVKHLNDA 217 S+P++ANG V DA Sbjct: 198 CSIPVIANGDVWLPEDA 214 >UniRef50_Q9VY45 Cluster: CG1434-PA; n=6; Endopterygota|Rep: CG1434-PA - Drosophila melanogaster (Fruit fly) Length = 473 Score = 73.3 bits (172), Expect = 4e-12 Identities = 58/211 (27%), Positives = 101/211 (47%), Gaps = 21/211 (9%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTT-----TDFPV 77 + APMVR + R L AD+ +T L D S R N + T +D + Sbjct: 27 ILAPMVRVGTLPMRLLALEMGADIVYTEE-LVDIKLIKSIRRPNPALGTVDFVDPSDGTI 85 Query: 78 IAQFAANNRDDFV------DAS------KLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLS 125 + + A V DA KL+ + G+D+N GCP+++++K G G +LL+ Sbjct: 86 VFRTCAQETSRLVLQMGTSDAGRALAVGKLLQRDISGLDINMGCPKEFSIKGGMGAALLA 145 Query: 126 KPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFL-TSMEEHCTK 184 P+ I++ L + L ++ KIR+L D++ T+ L Q+L G+ + + Sbjct: 146 DPDKAAHILRTLCSGL--DIPVTCKIRILPDVEGTIDLVQKLAATGIAAIGIHARTRDER 203 Query: 185 SSGPVDINGLKEVREALSVPMVANGGVKHLN 215 P L+ V +A+ +P++ANGG K+++ Sbjct: 204 PQHPAHPEVLRAVAQAVDIPIIANGGSKNMH 234 >UniRef50_Q4S086 Cluster: Chromosome undetermined SCAF14784, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14784, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 505 Score = 72.9 bits (171), Expect = 6e-12 Identities = 39/99 (39%), Positives = 53/99 (53%), Gaps = 2/99 (2%) Query: 27 MVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTT--DFPVIAQFAAN 84 MV S++ +R L R A LC+TPM A F +++ R + D P+I QF AN Sbjct: 1 MVDQSELAWRLLSRRHGAQLCYTPMFHAQVFVRDANYRRDNLYNEVCEEDRPLITQFCAN 60 Query: 85 NRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSL 123 + + FV A+ L Y D +DLN GCPQ A + YG L Sbjct: 61 DPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFL 99 Score = 52.8 bits (121), Expect = 6e-06 Identities = 27/75 (36%), Positives = 44/75 (58%), Gaps = 3/75 (4%) Query: 147 ISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVDINGLKEVREALSV 203 I+ KIR+ +++KTV Q LEK G LT +E +G ++ VR+A+++ Sbjct: 157 ITCKIRVFKEMEKTVRYAQMLEKAGCQLLTVHGRTKEQKGAMTGVASWEHIRAVRQAVNI 216 Query: 204 PMVANGGVKHLNDAT 218 P+ ANG ++HL+D T Sbjct: 217 PVFANGNIQHLSDVT 231 >UniRef50_Q6C002 Cluster: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 394 Score = 72.5 bits (170), Expect = 7e-12 Identities = 46/120 (38%), Positives = 69/120 (57%), Gaps = 3/120 (2%) Query: 60 NSKARANEFMTTTTDFP-VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDG 118 N++ +A F T+ + +I Q + N + V A K+V V G+DLNCGCP+ ++M G Sbjct: 68 NTEKKAIIFRTSEAERDKIIFQVGSANPEIAVAACKMVAKDVAGIDLNCGCPKHFSMHAG 127 Query: 119 YGCSLLSKPEIIYDIVKGLRNVL--PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176 G +LL P+ + I++ L + P SISVKIRLL +KT+ L +L + GV LT Sbjct: 128 MGAALLKTPDKLVAILEALVKEVGEPFNVSISVKIRLLETEEKTLELVDRLAQTGVKNLT 187 >UniRef50_O74731 Cluster: tRNA dihydrouridine synthase Dus2; n=1; Schizosaccharomyces pombe|Rep: tRNA dihydrouridine synthase Dus2 - Schizosaccharomyces pombe (Fission yeast) Length = 479 Score = 72.5 bits (170), Expect = 7e-12 Identities = 69/224 (30%), Positives = 107/224 (47%), Gaps = 32/224 (14%) Query: 22 KVC-APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQ--------NSKARANEFMTTT 72 KVC APMVR ++ R L + A+L + P I+ + N + +F+ Sbjct: 9 KVCLAPMVRIGELPMRLLALRYGANLVWGPEIVDKALLSGTPVERVVNDRINCIDFVKPP 68 Query: 73 TD---FPV--------IAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGC 121 ++ F V I Q + + + V+A+KLV V G+DLNCGCP+ +++ G G Sbjct: 69 SNKVLFRVHPLEANRLIFQLGSASPELAVEAAKLVANDVAGIDLNCGCPKHFSVHAGMGA 128 Query: 122 SLLSKPEIIYDIVKGLRNVL--PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSME 179 LL + + I+ L N + P K SIS KIRLL + T+ L +++ GV +T Sbjct: 129 GLLKNQDRLVSILDALVNEIGKPYKISISCKIRLLETKEDTLKLVERICDTGVRAIT--- 185 Query: 180 EHC----TKSSGPVDINGLKE---VREALSVPMVANGGVKHLND 216 HC +++ P D + L E V V ++ NG V ND Sbjct: 186 VHCRTTPMRNTEPADRSYLSEIVGVCRNKDVSILVNGDVLSYND 229 >UniRef50_A4RL93 Cluster: Putative uncharacterized protein; n=1; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 313 Score = 72.5 bits (170), Expect = 7e-12 Identities = 49/145 (33%), Positives = 71/145 (48%), Gaps = 20/145 (13%) Query: 76 PVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVK 135 P I QF AN + AS LV P+V GVDLNCGCPQ WA + G +L+ + E++ D+V Sbjct: 41 PTIVQFGANVPVELARASSLVAPFVAGVDLNCGCPQSWACAETLGAALMERRELVRDMVV 100 Query: 136 GLRNVL---------------PNKFSISVKIRLLNDIKKTVILCQQL----EKCGVTFLT 176 R+ L P S+SVKIR+ D++KT+ + + FLT Sbjct: 101 ETRSRLASDGWAVGLERDKNDPKGRSVSVKIRVHKDLRKTMDFIDTVIGDPNARNIDFLT 160 Query: 177 -SMEEHCTKSSGPVDINGLKEVREA 200 T S P+++ L + E+ Sbjct: 161 IHPRTRATPSREPINVESLSILVES 185 >UniRef50_A6DPY9 Cluster: Putative uncharacterized protein; n=1; Lentisphaera araneosa HTCC2155|Rep: Putative uncharacterized protein - Lentisphaera araneosa HTCC2155 Length = 330 Score = 72.1 bits (169), Expect = 1e-11 Identities = 50/181 (27%), Positives = 84/181 (46%), Gaps = 6/181 (3%) Query: 45 DLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAANNRDDFVDASKLVYPY-VDGV 103 DL T I S + ++ + + + D P+ Q NN + +++KLV D V Sbjct: 33 DLLCTEFIRISSHKPSMRSLKKQIVKSG-DIPLSVQIMGNNAELMAESAKLVVDCGADAV 91 Query: 104 DLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVI- 162 D+N GCP K A+K G G ++L P++ Y ++ +R +P ++S KIR D K+ V Sbjct: 92 DVNMGCPTKRAVKGGVGSAMLKDPKLCYQVLASMREQVP--CALSAKIRAGFDNKEGVFE 149 Query: 163 LCQQLEKCGVTFL-TSMEEHCTKSSGPVDINGLKEVREALSVPMVANGGVKHLNDATTYM 221 + Q + G +L G D + ++E +P++ NG V+ DA Sbjct: 150 ILQAIVDSGADYLAVHPRRRVDHYEGHSDWRIISALKEKSPIPVIGNGDVRTAADAVRMF 209 Query: 222 K 222 K Sbjct: 210 K 210 >UniRef50_Q74EF7 Cluster: Dihydrouridine synthase family protein; n=2; Deltaproteobacteria|Rep: Dihydrouridine synthase family protein - Geobacter sulfurreducens Length = 325 Score = 71.7 bits (168), Expect = 1e-11 Identities = 44/188 (23%), Positives = 84/188 (44%), Gaps = 1/188 (0%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 + APM + + FR L R A LCFT M+ + + K + D P+ Q Sbjct: 17 ILAPMAGITNLPFRLLAREQGAGLCFTEMVSVNGLVREGKKSFELLRSVPGDRPLGIQLF 76 Query: 83 ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 ++ D + V Y D +D+N GCP K + G G +L+ +P+ + IV+ +R Sbjct: 77 GDDPDVMGRVAATVDGYGDLIDINMGCPVKKVVGTGAGSALMREPDKVRAIVRAVRRATR 136 Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREAL 201 ++ ++ + + + + E+ G +T G D L E+++A+ Sbjct: 137 LPLTVKIRSGWSCEDANFIQIARIAEEEGCNAVTLHPRSRAQMFEGTADWTKLAELKQAV 196 Query: 202 SVPMVANG 209 ++P++ +G Sbjct: 197 AIPVIGSG 204 >UniRef50_Q31II6 Cluster: Dihydrouridine synthase; n=1; Thiomicrospira crunogena XCL-2|Rep: Dihydrouridine synthase - Thiomicrospira crunogena (strain XCL-2) Length = 320 Score = 71.3 bits (167), Expect = 2e-11 Identities = 50/202 (24%), Positives = 90/202 (44%), Gaps = 6/202 (2%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 APM + +R + R A + M+ + + S + T P I Q Sbjct: 15 APMAGITDRVYRDICRESGASYAVSEMVASKKQLRESAKSSTRHADKTETSPRIVQLLGT 74 Query: 85 NRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143 + ++ VDA+ D +DLN GCP K G +L+ +PE + DI K L + Sbjct: 75 HPEELVDAALWQQSQGADIIDLNMGCPAKKVCDVAAGSALMGQPERVADIFKSLTEAI-- 132 Query: 144 KFSISVKIRLLNDIK--KTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREA 200 ++VKIR D+ V + + ++ G+ +T K +G + + +K V++A Sbjct: 133 DLPVTVKIRTGTDVDNINAVEIAKLAQELGLKAITIHGRTRADKFNGQAEYDTIKAVKQA 192 Query: 201 LSVPMVANGGVKHLNDATTYMK 222 + +P++ANG + +A +K Sbjct: 193 VDIPVIANGDICSPKEAQFVLK 214 >UniRef50_A4XH30 Cluster: Putative TIM-barrel protein, nifR3 family; n=1; Caldicellulosiruptor saccharolyticus DSM 8903|Rep: Putative TIM-barrel protein, nifR3 family - Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903) Length = 328 Score = 71.3 bits (167), Expect = 2e-11 Identities = 57/201 (28%), Positives = 98/201 (48%), Gaps = 13/201 (6%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIA-QFAA 83 APM ++ FR+L F AD+ T M+ A + S+ + E ++ + D + Q Sbjct: 11 APMAGFTDKVFRSLCSRFGADVTVTEMVSAKAITMGSQ-KTKELISFSEDEKIKGVQIFG 69 Query: 84 NNRDDFVDASKLV---YPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140 ++ +A K++ + Y D +D+N GCP +K G G +L+ P + IV+ + V Sbjct: 70 SDPHVMAEAVKIIQDEFEY-DFIDINMGCPVPKVVKSGEGSALMKNPSLAAKIVEEVAKV 128 Query: 141 LPNKFSISVKIRLLND---IKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKE 196 ++ +SVKIR D I C +++ G +F+T T+ SG D +K Sbjct: 129 --SRKPVSVKIRKGFDEENINAPEFAC-IMQESGASFITVHGRTRTQMYSGKADWEIIKM 185 Query: 197 VREALSVPMVANGGVKHLNDA 217 V+E + +P+VANG + A Sbjct: 186 VKEKVKIPVVANGDIVDFESA 206 >UniRef50_A5DYF6 Cluster: Putative uncharacterized protein; n=1; Lodderomyces elongisporus NRRL YB-4239|Rep: Putative uncharacterized protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 504 Score = 71.3 bits (167), Expect = 2e-11 Identities = 59/193 (30%), Positives = 91/193 (47%), Gaps = 30/193 (15%) Query: 14 AKINKTYL-KVC-APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQN----------- 60 +K+ TY KVC APMVR ++ R L + DL ++P + Q Sbjct: 3 SKMALTYTNKVCLAPMVRSGELPIRLLALRYGCDLVWSPEYIDRKIIQTQRRVNAELNTI 62 Query: 61 ----------SKARANEFMTTTTDFP-----VIAQFAANNRDDFVDASKLVYPYVDGVDL 105 SK + N+ P +I Q + + V+A+ V VDG+DL Sbjct: 63 DYIIPNNKDPSKMKHNQDNVVFRKHPEETGKLIFQLGTSTPELAVEAALRVIEDVDGIDL 122 Query: 106 NCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL--PNKFSISVKIRLLNDIKKTVIL 163 NCGCP+ ++ G G LL P+I+ I++ L + PNK IS KIRLL + + + +L Sbjct: 123 NCGCPKSFSTHGGMGAELLKTPDILCSILRALVEKVGNPNKKPISCKIRLLPNFEASKLL 182 Query: 164 CQQLEKCGVTFLT 176 +Q+ + G+ LT Sbjct: 183 IEQICQTGIRNLT 195 >UniRef50_A1SX05 Cluster: Dihydrouridine synthase, DuS; n=3; Alteromonadales|Rep: Dihydrouridine synthase, DuS - Psychromonas ingrahamii (strain 37) Length = 314 Score = 70.9 bits (166), Expect = 2e-11 Identities = 49/157 (31%), Positives = 78/157 (49%), Gaps = 7/157 (4%) Query: 71 TTTDFPVIAQFAANNRDDFVD-ASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129 T + PV Q N + A + + DG+DLN GCP K K+ G LL PE Sbjct: 59 TASGTPVRIQLLGQNPQCLAENAHQAISIGSDGIDLNFGCPAKTVNKNKGGAVLLKSPEA 118 Query: 130 IYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVI-LCQQLEKCGVTFLTSMEEHCTKSSG- 187 +Y IV +R +P ++SVKIRL + K I Q ++ G L TK+ G Sbjct: 119 LYQIVTEVRKAVPVFQTLSVKIRLGYEDKSLAIENAQAIQAAGADELAVHAR--TKAEGY 176 Query: 188 --PVDINGLKEVREALSVPMVANGGVKHLNDATTYMK 222 P + + ++++A+++P+ ANG + ++DA M+ Sbjct: 177 RPPAHWHWIAKIKDAITIPVTANGDIFSVDDAKRCME 213 >UniRef50_Q550J6 Cluster: Putative uncharacterized protein; n=2; Dictyostelium discoideum|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 392 Score = 70.9 bits (166), Expect = 2e-11 Identities = 42/144 (29%), Positives = 76/144 (52%), Gaps = 6/144 (4%) Query: 15 KINKTYLKVCAPMVRYSKVHFRTLVRNF--NADLCFTPMILADSFCQNSKARANEFMTTT 72 K++K + APM + + FR L+ N ++ F + AD +N +A ++ +T Sbjct: 7 KLSKPIFSL-APMADVTDISFRFLLANCMGKPNVIFNEFVSADGLARNREALIDKLGYST 65 Query: 73 TDFPVIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAM--KDGYGCSLLSKPEI 129 + P++AQF N + F +++K+ DGVD+N GCP + + K G +L++ P + Sbjct: 66 QEKPIVAQFFGNKPEYFYESAKIANELGYDGVDINMGCPSRKVLSPKQASGAALITNPSL 125 Query: 130 IYDIVKGLRNVLPNKFSISVKIRL 153 +IVK + L + +SVK R+ Sbjct: 126 AKEIVKITKEALNFEKPVSVKTRI 149 >UniRef50_Q4PIC3 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 364 Score = 70.9 bits (166), Expect = 2e-11 Identities = 63/208 (30%), Positives = 92/208 (44%), Gaps = 26/208 (12%) Query: 18 KTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILA-----DSFCQNSKARANEFMTTT 72 ++ L APMV S + FR A L +T M LA D + S ++ E + Sbjct: 10 ESLLYCAAPMVGQSDLAFRLQTVQNGATLTWTQMYLAPELSSDQYMLESLLKSLEMGSNA 69 Query: 73 T--------------DFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDG 118 T P + Q A NN V+A++ V PY D +DLN GCPQ+ A + Sbjct: 70 TKNMARYRASPLHDQSAPQVVQLAGNNVQQLVEAARRVAPYADAIDLNLGCPQRHAEQGH 129 Query: 119 YGCSLLSKPE--IIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176 YG LL K ++ +IV G+ V I+ KIRL ++T L L G + +T Sbjct: 130 YGACLLPKQNWPLVAEIVSGM--VQAVDVPITTKIRLPVPKEQTAQLAVMLAHAGSSLVT 187 Query: 177 ---SMEEHCTKSSGPVDINGLKEVREAL 201 + G D++ + +VREAL Sbjct: 188 VHPRFASSARRRKGLADLDQVVKVREAL 215 >UniRef50_Q7MXX6 Cluster: TIM-barrel protein, putative, NifR3 family; n=23; Bacteroidetes/Chlorobi group|Rep: TIM-barrel protein, putative, NifR3 family - Porphyromonas gingivalis (Bacteroides gingivalis) Length = 333 Score = 70.5 bits (165), Expect = 3e-11 Identities = 53/193 (27%), Positives = 88/193 (45%), Gaps = 8/193 (4%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 APM + V FR + + F ADL ++ + AD+ + + ++ P+ Q Sbjct: 16 APMEDVTDVAFRIMCKQFGADLVYSEFLSADALIRQVAGTFRKMAIDESERPMAVQIYGR 75 Query: 85 NRDDFVDASKLVYPYVDG-VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143 + V+A++L +DLN GCP K G G +L ++ +I + + V Sbjct: 76 DVASMVEAARLCESAGPNLIDLNFGCPVKRVAGKGAGSGMLRNIPLMIEITREV--VKAV 133 Query: 144 KFSISVKIRL--LNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE- 199 K ++VK RL ND K V L +QL+ CG+ LT +G D + EV+ Sbjct: 134 KLPVTVKTRLGWDNDSKIIVDLAEQLQDCGIAALTIHGRTRAQMYTGTADWTLIGEVKNN 193 Query: 200 -ALSVPMVANGGV 211 + +P++ NG V Sbjct: 194 PRMQIPIIGNGDV 206 >UniRef50_Q6BX60 Cluster: Debaryomyces hansenii chromosome B of strain CBS767 of Debaryomyces hansenii; n=1; Debaryomyces hansenii|Rep: Debaryomyces hansenii chromosome B of strain CBS767 of Debaryomyces hansenii - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 374 Score = 70.5 bits (165), Expect = 3e-11 Identities = 53/172 (30%), Positives = 90/172 (52%), Gaps = 20/172 (11%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSF--CQ---NSKARANEFMTTTTD----- 74 APMVR ++ R + + ADL +TP I+ C+ N +F+ Sbjct: 11 APMVRSGEIPTRLMALRYGADLVWTPEIVDKKLIKCERVINDDLGTVDFLDPNKKVVFRT 70 Query: 75 FP------VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPE 128 +P +I Q + + + V A+K+V VDG+DLNCGCP+ ++ G G +LL+ P+ Sbjct: 71 YPAEELGKLIFQIGSADPELAVQAAKIVAQDVDGIDLNCGCPKPFSTHSGMGAALLTTPD 130 Query: 129 IIYDIVKGLRNVLPNKFS--ISVKIRLLN--DIKKTVILCQQLEKCGVTFLT 176 ++ I++ L + + + IS KIRLL+ D+ ++ L +L K G++ LT Sbjct: 131 LLELILRNLVSEVGKVYDIPISAKIRLLDDTDVTPSLELIDRLCKTGISNLT 182 >UniRef50_O67533 Cluster: Probable tRNA-dihydrouridine synthase; n=1; Aquifex aeolicus|Rep: Probable tRNA-dihydrouridine synthase - Aquifex aeolicus Length = 316 Score = 70.5 bits (165), Expect = 3e-11 Identities = 51/198 (25%), Positives = 92/198 (46%), Gaps = 5/198 (2%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 + APM Y+ FR L R AD +T +I A +N + T + P+ Q Sbjct: 9 ILAPMASYTHSAFRRLCRRLGADRTYTELISAVGVLRNGIPMKLAYFTEE-ERPIHIQVF 67 Query: 83 ANNRDDFVDASKLVYPYV--DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140 +N ++ AS ++ + D +D+N GC +++ +L P ++ ++VK Sbjct: 68 GSNPEEIAQASVVIAKELKPDFIDINFGCSVPKVLRNKAAGYMLQCPPLMGEVVKETVEA 127 Query: 141 L-PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVR 198 L P +S KIRL + + + ++L+K GV+ + + SG + +KE + Sbjct: 128 LKPYGIPVSAKIRLGFEKDEVERIVEELQKAGVSLIAIHARTAKQGFSGKALWHRIKEAK 187 Query: 199 EALSVPMVANGGVKHLND 216 + SVP++ +G VK D Sbjct: 188 KVASVPIIGSGDVKSWRD 205 >UniRef50_Q899H0 Cluster: Nitrogen regulation protein nifR3; n=24; Clostridia|Rep: Nitrogen regulation protein nifR3 - Clostridium tetani Length = 322 Score = 70.1 bits (164), Expect = 4e-11 Identities = 50/210 (23%), Positives = 92/210 (43%), Gaps = 7/210 (3%) Query: 15 KINKTYLK---VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTT 71 KI++ LK AP+ + + FR L + L +T M+ A + +S + + Sbjct: 2 KISRLELKGNVFLAPLAGVTDLAFRGLCKRMGCTLVYTEMVSAKALFYDSDKTKDMLRFS 61 Query: 72 TTDFPVIAQFAANNRDDFVDASKLVYPYVDGV---DLNCGCPQKWAMKDGYGCSLLSKPE 128 + P+ Q D + + + D V D+N GCP +K+G G +L+ P+ Sbjct: 62 KEELPIAVQIFGKEPDIMANVVEKYFNSNDNVCLIDINMGCPAPKIVKNGEGSALMKNPK 121 Query: 129 IIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SG 187 + DIV+ ++ V ++ + ND + + +E G LT + G Sbjct: 122 LASDIVESIKKVSTKPVTVKFRKGFDNDNINALEFAKIMENSGADALTIHGRTREQMYQG 181 Query: 188 PVDINGLKEVREALSVPMVANGGVKHLNDA 217 D +K+V+E++ +P++ NG V DA Sbjct: 182 KADWEIIKKVKESVKIPVIGNGDVFTGEDA 211 >UniRef50_Q47C15 Cluster: Dihydrouridine synthase, DuS; n=2; Betaproteobacteria|Rep: Dihydrouridine synthase, DuS - Dechloromonas aromatica (strain RCB) Length = 319 Score = 70.1 bits (164), Expect = 4e-11 Identities = 46/151 (30%), Positives = 77/151 (50%), Gaps = 7/151 (4%) Query: 71 TTTDFPVIAQFAANNRDDFVD-ASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129 T T P+ Q ++ + A +LV GVDLN GCP + G +LL +PE+ Sbjct: 60 TRTGTPMRVQLLGSDPHFMAENARRLVALNPAGVDLNFGCPAPTVFRHRGGSALLGEPEL 119 Query: 130 IYDIVKGLRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSG- 187 + +I +R+V+P + K+RL ++D + + Q LE G+ L + T+S G Sbjct: 120 LNEITSAVRSVVPAHIPFTAKMRLGIDDTSRAIDCAQALEAAGINEL--IVHGRTRSDGY 177 Query: 188 --PVDINGLKEVREALSVPMVANGGVKHLND 216 P + +VR+A+ +P++ANG V + D Sbjct: 178 RPPARWEWIDKVRDAIHIPLIANGEVWTVED 208 >UniRef50_Q1IVR5 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3; n=2; Acidobacteria|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 - Acidobacteria bacterium (strain Ellin345) Length = 370 Score = 69.7 bits (163), Expect = 5e-11 Identities = 56/202 (27%), Positives = 93/202 (46%), Gaps = 10/202 (4%) Query: 23 VCAPMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQNSKARANEFMTTT-TDFPVIAQ 80 V APM + FR +RN L T AD + +A+A ++T + P+ AQ Sbjct: 35 VLAPMAGVTDTVFRRFIRNLGGCGLMMTEFTSADGLARMREAKARRYLTFYGNERPISAQ 94 Query: 81 FAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139 ++ + DA+K+V D VDLN GCP K +K G LL I I + +R Sbjct: 95 LFGSDAETLADAAKVVQDLGFDLVDLNLGCPSKRVVKCNGGSGLLRDLPQIKVIFESVRK 154 Query: 140 VLPNKFSISVKIRLLNDIKKTVI--LCQQLEKCGVTFLTSMEEHCTKS--SGPVDINGLK 195 + F +VK R + K+ V L + E CG+ +M + SG + + Sbjct: 155 AVTIPF--TVKFRAGWNEKELVFLELAKLAENCGLN-AVAMHARTREQGYSGQANWGWIA 211 Query: 196 EVREALSVPMVANGGVKHLNDA 217 ++++ + +P++ NG ++ DA Sbjct: 212 DLKQVVKIPVIGNGDIRTPEDA 233 >UniRef50_A6BZR9 Cluster: Predicted TIM-barrel enzyme, possibly dehydrogenase, nifR3 family protein; n=1; Planctomyces maris DSM 8797|Rep: Predicted TIM-barrel enzyme, possibly dehydrogenase, nifR3 family protein - Planctomyces maris DSM 8797 Length = 355 Score = 69.7 bits (163), Expect = 5e-11 Identities = 47/197 (23%), Positives = 89/197 (45%), Gaps = 4/197 (2%) Query: 25 APMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83 AP+ Y++ FR +R LC T ++LA S+ T+ D P+ Q Sbjct: 28 APLAGYTQHAFRVAIRELGGVGLCTTDLVLASHLLSGSRKSKALLTTSPADRPLTIQIFG 87 Query: 84 NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 + V A++ + + VDLN GCP +G G ++ P+ +V + + + Sbjct: 88 GITAELVAAARWLEQHGYAAVDLNMGCPMAKINGNGGGARIMCAPDAACQLVAEVVDAVS 147 Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVREAL 201 ++ +++ D +L ++ E+ GV +T + G VD+ G+++ EA+ Sbjct: 148 IPVTVKMRLGWDRDSITAPLLAREFEQAGVAAITVHGRTRNQGFGGTVDLQGIRQTVEAV 207 Query: 202 -SVPMVANGGVKHLNDA 217 +P++ NG V + DA Sbjct: 208 QQIPVIGNGDVCTVEDA 224 >UniRef50_A6CBK4 Cluster: Predicted TIM-barrel enzyme, possibly dehydrogenase, nifR3 family protein; n=1; Planctomyces maris DSM 8797|Rep: Predicted TIM-barrel enzyme, possibly dehydrogenase, nifR3 family protein - Planctomyces maris DSM 8797 Length = 365 Score = 69.3 bits (162), Expect = 7e-11 Identities = 53/204 (25%), Positives = 95/204 (46%), Gaps = 8/204 (3%) Query: 25 APMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83 +P+ Y+ + FR +VR L T ++ A + S+ T D P Q Sbjct: 33 SPLAGYTNLPFRRIVRELGGVGLATTDLVNARGLLEGSEKTLQLTQTCPEDSPFAVQIFG 92 Query: 84 NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 + DA++L+ V +D+N GCP +K G G S++ +P +V+ + + Sbjct: 93 SEPQQMKDAAQLLESRGVHSIDINMGCPVNRIVKGGAGASMMCRPSDTVSLVQTVVEAV- 151 Query: 143 NKFSISVKIRLLNDIKK--TVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVRE 199 K +SVK+RL D + ++ EK GV + + G V+ +G++ V E Sbjct: 152 -KIPVSVKMRLGWDDSELSAPFFSREFEKVGVVAVAIHGRTREQGFRGVVNHDGIRRVVE 210 Query: 200 AL-SVPMVANGGVKHLNDATTYMK 222 A+ S+P++ NG V ++ +A +K Sbjct: 211 AVDSIPVIGNGDVTNVAEADFMLK 234 >UniRef50_Q6SFW7 Cluster: NifR3/Smm1 family protein; n=1; uncultured bacterium 578|Rep: NifR3/Smm1 family protein - uncultured bacterium 578 Length = 322 Score = 68.9 bits (161), Expect = 9e-11 Identities = 41/189 (21%), Positives = 84/189 (44%), Gaps = 2/189 (1%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 APM S FR + R A L + M++ N+ + + P+ Q A + Sbjct: 15 APMAGTSDKPFRMICREQGAALTTSEMVVMQKHLLNTNKSKHRLDFRSEQSPISIQIAGS 74 Query: 85 NRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143 + +++K + D +D+N GCP K G +L+ +++ DI+K + N + Sbjct: 75 ESQELAESAKQALEFGADIIDINMGCPAKKVCNKAAGSALMKNEKLVEDIIKAVVNAVNI 134 Query: 144 KFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREALS 202 ++ ++ + K + + E G+ L K +G + + +K+++ +S Sbjct: 135 PVTLKMRTGWNEENKNAPTIAKIAEDNGIKMLAIHGRTRAQKYNGDAEYDTVKKIKGIVS 194 Query: 203 VPMVANGGV 211 +P+VANG + Sbjct: 195 IPVVANGDI 203 >UniRef50_Q0YFW9 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3; n=8; Desulfuromonadales|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 - Geobacter sp. FRC-32 Length = 343 Score = 68.9 bits (161), Expect = 9e-11 Identities = 49/192 (25%), Positives = 88/192 (45%), Gaps = 5/192 (2%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 + APM + + R L R A L FT MI + + K + D P+ Q Sbjct: 34 ILAPMAGLTNLPMRILARECGAALTFTEMISVNGLVREGKKTFDLLRRDPMDRPMGIQIF 93 Query: 83 ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 ++ + ++LV Y + +D+N GCP + + G G +LL +P + I+K +R Sbjct: 94 GDDPQLLAEGARLVEQYGELIDINMGCPVRKVVGSGAGSALLREPAKVGMIIKAVRKA-- 151 Query: 143 NKFSISVKIRL-LNDIKKTVILCQQL-EKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE 199 +++KIR T + ++ E GV +T G D + ++E++E Sbjct: 152 TSLPLTIKIRTGWGAADHTFLEIGRIAEAEGVDGVTLHPRSRAQMFEGHADWSRIRELKE 211 Query: 200 ALSVPMVANGGV 211 ALS+P++ +G + Sbjct: 212 ALSIPVIGSGDI 223 >UniRef50_A2DYY3 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 313 Score = 68.5 bits (160), Expect = 1e-10 Identities = 52/212 (24%), Positives = 100/212 (47%), Gaps = 21/212 (9%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANE--------------- 67 + APMVR S + FR + ADL F+P ++ + ++ + + Sbjct: 14 IAAPMVRGSSLSFRLACLEYGADLVFSPGLVDLAIIGSTMEKDDNNISLIKVENGHNRRI 73 Query: 68 FMTTTTDF-PVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSK 126 F TT + +I Q + + + A+ + + G+D+NCGCP+ +A G G + + Sbjct: 74 FHTTAEERGKLIIQLITVDGPNAIKAADMCTEFASGIDINCGCPESFACHRGGGSKM--Q 131 Query: 127 PEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEE-HCTKS 185 E D+VK L+ + + ISVK+R+ + +++++ + + G +T K Sbjct: 132 LESAVDVVKTLK--MNSPLPISVKMRVKDTVEESLQFAKAMVDAGAVAITVHGRLAADKR 189 Query: 186 SGPVDINGLKEVREALSVPMVANGGVKHLNDA 217 G VD +KE+ + ++ + NGG+ + DA Sbjct: 190 HGSVDYEHMKEIFDNINCAKIGNGGICNKADA 221 >UniRef50_Q5ZRM0 Cluster: Nitrogen regulation protein; n=4; Legionella pneumophila|Rep: Nitrogen regulation protein - Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM 7513) Length = 329 Score = 67.7 bits (158), Expect = 2e-10 Identities = 46/192 (23%), Positives = 88/192 (45%), Gaps = 6/192 (3%) Query: 26 PMVRYSKVHFRTLVRNFNADL-CFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 P+ YS FR L + C + M A +++ T+ + Q + N Sbjct: 25 PLAGYSCAPFRDLFNIYTPPAYCVSEMCSAIDILHKHSSQSRYIYRAPTEKFLAYQISGN 84 Query: 85 NRDDFVDAS-KLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143 +A+ KL D +D+NCGCP+ K G G +LL P+ + I+ +R + Sbjct: 85 EPHVLAEAAAKLQSLGADLIDINCGCPKSKIRKKGAGSALLEDPQKLIAIISRVRAAI-- 142 Query: 144 KFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSG-PVDINGLKEVREALS 202 +++KIR+ N+ +K + L +Q+E G L T+ P + + ++ A++ Sbjct: 143 SIPLTIKIRIQNN-EKDLTLAKQIEDAGAHALIVHGRRWTEDYDIPCNWQQIANIKNAVN 201 Query: 203 VPMVANGGVKHL 214 +P++ NG + ++ Sbjct: 202 IPVIVNGDINNI 213 >UniRef50_Q0FAI7 Cluster: tRNA-dihydrouridine synthase, putative; n=1; alpha proteobacterium HTCC2255|Rep: tRNA-dihydrouridine synthase, putative - alpha proteobacterium HTCC2255 Length = 324 Score = 67.7 bits (158), Expect = 2e-10 Identities = 46/201 (22%), Positives = 91/201 (45%), Gaps = 4/201 (1%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSK-ARANEFMTTTTDFPVIAQFAA 83 +P+ + + +R LV +F A L + M+ + Q K ARA + + + Q A Sbjct: 14 SPLAGITDLPYRNLVSSFGAGLVVSEMVASHEIMQKGKDARARAELGFNVEGTSV-QIAG 72 Query: 84 NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 + + +KL+ +D+N GCP K + G +L+ P++ +++ + N + Sbjct: 73 RDAFWMSECAKLIEGNGAKIIDINMGCPAKSVVNGASGSALMRTPDLALKLIEAVVNAVD 132 Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREAL 201 ++ ++ ++ L EK G+ +T C G D ++EV+EA+ Sbjct: 133 IPVTLKTRLGWDHNDLNAADLSSSAEKIGIQMITIHGRTRCQFYKGDADWRKIREVKEAV 192 Query: 202 SVPMVANGGVKHLNDATTYMK 222 ++P++ANG + A MK Sbjct: 193 NIPVIANGDIIDTPTAKLAMK 213 >UniRef50_Q14SX5 Cluster: Putative dihydrouridine synthase; n=1; Ruminococcus flavefaciens|Rep: Putative dihydrouridine synthase - Ruminococcus flavefaciens Length = 332 Score = 67.3 bits (157), Expect = 3e-10 Identities = 49/191 (25%), Positives = 84/191 (43%), Gaps = 5/191 (2%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 APM + +R + + + A + M+ A C + + A T + P+ Q + Sbjct: 19 APMAGVADRAYRLMCKRYGAAYVVSEMVSAKGICYSDRKTAELCTVTEEERPMAVQLFGS 78 Query: 85 NRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143 D +A K+V Y D +D+N GCP + G G +L+ P + I + + Sbjct: 79 EPDFMAEAVKIVLDYRPDIIDINMGCPVPKVVGTGAGSALMKDPALAAAITEAAVKAAGD 138 Query: 144 KFSISVKIRL--LNDIKKTVILCQQLEKCGVTFLTSM-EEHCTKSSGPVDINGLKEVREA 200 ++VKIR +D + + LE G + SG D+N +K V+EA Sbjct: 139 T-PVTVKIRSGWSSDSINAPEMARALEASGTAAIAVHGRTRDMFYSGQSDMNVIKAVKEA 197 Query: 201 LSVPMVANGGV 211 +SVP++ NG + Sbjct: 198 VSVPVIGNGDI 208 >UniRef50_Q5M689 Cluster: Possible transcriptional regulator; n=20; Streptococcus|Rep: Possible transcriptional regulator - Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) Length = 350 Score = 66.5 bits (155), Expect = 5e-10 Identities = 55/201 (27%), Positives = 90/201 (44%), Gaps = 9/201 (4%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 V APM + FRT+ + F+A L MI N++ + + P+ Q Sbjct: 45 VLAPMAGVTNSAFRTIAKEFSAGLVVMEMISEKGLLYNNEKTLHMLHIDENEHPMSIQLF 104 Query: 83 ANNRDDFVDASKLVYPYV--DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140 + + A+ + D VD+N GCP +K+ G L P+ IY IVK + +V Sbjct: 105 GGDAEGLKRAADFIQTNTKADIVDINMGCPVNKVVKNEAGAKWLKDPDKIYHIVKEVTSV 164 Query: 141 LPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS--SGPVDINGLKEV 197 L ++VK+R +D V E GV+ L +M + +G D L V Sbjct: 165 L--DIPLTVKMRTGWSDSDLAVENALAAESAGVSAL-AMHGRTREQMYTGHCDHETLARV 221 Query: 198 REALS-VPMVANGGVKHLNDA 217 +A++ +P + NG V+++ DA Sbjct: 222 AKAITKIPFIGNGDVRNVQDA 242 >UniRef50_A0LJ96 Cluster: Putative TIM-barrel protein, nifR3 family; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Putative TIM-barrel protein, nifR3 family - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 352 Score = 66.5 bits (155), Expect = 5e-10 Identities = 46/192 (23%), Positives = 87/192 (45%), Gaps = 3/192 (1%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTT-TTDFPVIAQF 81 V APM + +R L+ +F A + T M+ +N +A + P+ Q Sbjct: 25 VLAPMAGVTDSAYRALMADFGAAMVTTEMVSIQGLVRNQRATLDLCRQQHPVGVPLAVQV 84 Query: 82 AANNRDDFVDASKLVYPYVDG-VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140 + +A++LV +D+N GCP + ++ G G LL P+ + +V+ ++ Sbjct: 85 FGRDPAVMAEAARLVEQGGAALIDINAGCPVRKVVRQGAGAILLKDPDRLAAMVEAVKRA 144 Query: 141 LPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVRE 199 + ++ +++ N L +QL GV +T + SG D + + EV+ Sbjct: 145 VSVPVTVKIRVGWDNAANGVAGLARQLVSAGVDAITVHGRTAAQMYSGRADWSRIAEVKA 204 Query: 200 ALSVPMVANGGV 211 A++VP++ NG V Sbjct: 205 AVAVPVIGNGDV 216 >UniRef50_Q64MI4 Cluster: Putative TIM-barrel enzyme; n=3; Bacteroidales|Rep: Putative TIM-barrel enzyme - Bacteroides fragilis Length = 324 Score = 66.1 bits (154), Expect = 7e-10 Identities = 48/193 (24%), Positives = 87/193 (45%), Gaps = 8/193 (4%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 APM + FR + + F AD+ +T + +D+ ++ + + PV Q Sbjct: 16 APMEDVTDPAFRLMCKKFGADMVYTEFVSSDALIRSVNKTTQKLTICDEERPVAIQIYGK 75 Query: 85 NRDDFVDASKLVYP-YVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143 + + V A+++V D +D+N GCP K G G +L + +I + + + + Sbjct: 76 DTEAMVGAARIVEEAQPDILDINFGCPVKKVAGKGAGAGMLQNIPKMLEITRAVVDAV-- 133 Query: 144 KFSISVKIRLLNDIKKTVI--LCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE- 199 K ++VK RL D +I L +QL+ CG+ L +G D + EV+ Sbjct: 134 KIPVTVKTRLGWDADHKIIVDLAEQLQDCGIAALAIHGRTRAQMYTGEADWTLIGEVKNN 193 Query: 200 -ALSVPMVANGGV 211 + +P++ NG V Sbjct: 194 PRMHIPIIGNGDV 206 >UniRef50_Q6MNE4 Cluster: Dihydrouridine synthase family protein; n=1; Bdellovibrio bacteriovorus|Rep: Dihydrouridine synthase family protein - Bdellovibrio bacteriovorus Length = 323 Score = 65.7 bits (153), Expect = 9e-10 Identities = 44/147 (29%), Positives = 75/147 (51%), Gaps = 9/147 (6%) Query: 76 PVIAQFAANNRDDF-VDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134 PV Q + ++A + V GVDLN GCP K + G SLL + +++IV Sbjct: 64 PVFVQLLGGQAEPLALNAQRAVKLGALGVDLNFGCPAKTVNRHDGGASLLKSCDRVFNIV 123 Query: 135 KGLRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHC-TKSSG---PV 189 +R +P ++ KIRL +D K + + Q +E+ T+LT HC TK+ G P Sbjct: 124 DTVRKAVPADVPVTAKIRLGFDDPTKCLEIAQAVEEANATWLT---VHCRTKTDGYKPPA 180 Query: 190 DINGLKEVREALSVPMVANGGVKHLND 216 + + +++E + ++ANG + ++ D Sbjct: 181 YWDWIPKIKEKTKIKLIANGEIWNVAD 207 >UniRef50_Q0B0N8 Cluster: Putative TIM-barrel protein, NifR3 family; n=2; Clostridiales|Rep: Putative TIM-barrel protein, NifR3 family - Syntrophomonas wolfei subsp. wolfei (strain Goettingen) Length = 318 Score = 65.7 bits (153), Expect = 9e-10 Identities = 55/202 (27%), Positives = 98/202 (48%), Gaps = 9/202 (4%) Query: 22 KVCA-PMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDF-PVIA 79 +VCA PM S +R L R+F L + M+ +D + R ++ ++ + PV Sbjct: 12 RVCAAPMAGVSDKAYRVLARDFGCGLVCSEMV-SDKGLVYGQGRTSKIADSSGEKRPVAV 70 Query: 80 QFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLR 138 Q + + A+++V D +D+N GCP +K+G G +L+ IV+ + Sbjct: 71 QIFGSEAESMATAARIVEEMGADIIDINMGCPTPKIVKNGEGAALMLDITKSRGIVREVL 130 Query: 139 NVLPNKFSISVKIRLLNDIKKT--VILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLK 195 V+ K ++VK+R D + L Q+LE+ GV + + SG D N +K Sbjct: 131 RVV--KVPVTVKMRKGWDENSINCLELAQKLEEEGVAAICLHPRSRQQFFSGSADWNLIK 188 Query: 196 EVREALSVPMVANGGVKHLNDA 217 E+++ L +P++ NG + +DA Sbjct: 189 EMKKELKIPVIGNGDIWSADDA 210 >UniRef50_Q9JUP6 Cluster: tRNA-dihydrouridine synthase C; n=4; Neisseria|Rep: tRNA-dihydrouridine synthase C - Neisseria meningitidis serogroup A Length = 333 Score = 65.7 bits (153), Expect = 9e-10 Identities = 46/151 (30%), Positives = 74/151 (49%), Gaps = 7/151 (4%) Query: 71 TTTDFPVIAQFAANNRDDFV-DASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129 T + P Q ++ D+ +A + V D +DLN GCP + G LL +PE+ Sbjct: 71 TFSGTPCTVQLLGSDADNMAANALEAVRFGADKIDLNFGCPAPTVNRHKGGAILLKEPEL 130 Query: 130 IYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQ-QLEKCGVTFLTSMEEHCTKSSG- 187 I+ IVK LR LP ++ K+RL + K + C + + G LT TK+ G Sbjct: 131 IFHIVKTLRERLPAHIPLTAKMRLGYEDKSPALECACAIAEGGACGLTVHAR--TKAEGY 188 Query: 188 --PVDINGLKEVREALSVPMVANGGVKHLND 216 P ++++R+++ +P+ ANG V L D Sbjct: 189 EPPAHWEWIRKIRDSVDIPVTANGDVFSLQD 219 >UniRef50_Q8ZAX7 Cluster: tRNA-dihydrouridine synthase B; n=214; Proteobacteria|Rep: tRNA-dihydrouridine synthase B - Yersinia pestis Length = 321 Score = 65.7 bits (153), Expect = 9e-10 Identities = 45/195 (23%), Positives = 90/195 (46%), Gaps = 10/195 (5%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILAD-SFCQNSKARANEFMTTTTDFPVI--A 79 + APM + FR L A + + M+ ++ + K+R D P I Sbjct: 13 IAAPMAGITDRPFRALCHGMGAGMAVSEMLSSNPEVWRTDKSRLR---MVHVDEPGIRNV 69 Query: 80 QFAANNRDDFVDASKL-VYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLR 138 Q A N+ D+ A+++ V +D+N GCP K + G +LL P+++ I+ + Sbjct: 70 QIAGNDPDEMAAAARINVASGAQIIDINMGCPAKKVNRKLAGSALLQHPDLVKQILSAVV 129 Query: 139 NVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT--SMEEHCTKSSGPVDINGLKE 196 N + ++ ++ + + + + Q E CG+ LT C +G + + ++ Sbjct: 130 NAVDVPVTLKIRTGWSPEHRNCIEIAQLAENCGIQALTIHGRTRSCL-FNGEAEYDSIRA 188 Query: 197 VREALSVPMVANGGV 211 V++ +S+P++ANG + Sbjct: 189 VKQTVSIPVIANGDI 203 >UniRef50_P37567 Cluster: Probable tRNA-dihydrouridine synthase 1; n=31; Bacilli|Rep: Probable tRNA-dihydrouridine synthase 1 - Bacillus subtilis Length = 333 Score = 65.7 bits (153), Expect = 9e-10 Identities = 48/198 (24%), Positives = 83/198 (41%), Gaps = 3/198 (1%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 V APM FR V+ F A L M+ + N+ + P+ Q Sbjct: 14 VLAPMAGVCNSAFRLTVKEFGAGLVCAEMVSDKAILYNNARTMGMLYIDEREKPLSLQIF 73 Query: 83 ANNRDDFVDASKLV--YPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140 ++ V+A+K V D +D+N GCP K G L P+ IY++V + + Sbjct: 74 GGKKETLVEAAKFVDQNTTADIIDINMGCPVPKITKCDAGAKWLLDPDKIYEMVSAVVDA 133 Query: 141 LPNKFSISVKIRLLNDIKKTVILCQQLEKC-GVTFLTSMEEHCTKSSGPVDINGLKEVRE 199 + ++ +++ D V Q +E+ G G + + +KEV++ Sbjct: 134 VNKPVTVKMRMGWDEDHIFAVKNAQAVERAGGKAVALHGRTRVQMYEGTANWDIIKEVKQ 193 Query: 200 ALSVPMVANGGVKHLNDA 217 ++S+P++ NG VK DA Sbjct: 194 SVSIPVIGNGDVKTPQDA 211 >UniRef50_A6LGT0 Cluster: Putative TIM-barrel enzyme; n=1; Parabacteroides distasonis ATCC 8503|Rep: Putative TIM-barrel enzyme - Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC11152) Length = 329 Score = 65.3 bits (152), Expect = 1e-09 Identities = 47/193 (24%), Positives = 88/193 (45%), Gaps = 8/193 (4%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 APM + + FR + + F AD+ +T + +D+ ++ + + + PV Q Sbjct: 16 APMEDVTDISFRLMCKRFGADMVYTEFVSSDALIRSVNKTQQKLNVSDDERPVAIQIYGK 75 Query: 85 NRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143 + V+A+++ D +D+N GCP K G G +L ++ +I + + V Sbjct: 76 DVASMVEAARICEEARPDILDINFGCPVKKVAGKGAGAGMLRNIPLMLEITREV--VKAV 133 Query: 144 KFSISVKIRLLNDIKKTVI--LCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE- 199 ++VK RL D VI L +QL+ CG+ L+ +G D ++ V+ Sbjct: 134 NIPVTVKTRLGWDADNRVIVDLAEQLQDCGIAALSIHGRTRAQMYTGEADWTLIRAVKNN 193 Query: 200 -ALSVPMVANGGV 211 + +P++ NG V Sbjct: 194 PRMQIPIIGNGDV 206 >UniRef50_Q7R3H4 Cluster: GLP_158_49916_51304; n=1; Giardia lamblia ATCC 50803|Rep: GLP_158_49916_51304 - Giardia lamblia ATCC 50803 Length = 462 Score = 65.3 bits (152), Expect = 1e-09 Identities = 50/167 (29%), Positives = 80/167 (47%), Gaps = 12/167 (7%) Query: 22 KVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKAR---ANEFM-TTTTDFPV 77 K APMV S++ +R L R + +L +TPM ++ +SKA +E + D P+ Sbjct: 19 KGIAPMVDGSELPYRLLTRRYGVELAWTPMHSTNTLVTSSKAMTQLVDELKHGESIDRPL 78 Query: 78 IAQFAANNRDDFVDASKLVYPY-----VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYD 132 + Q + NN +F A + D V+LN GCPQ A++ YG L+ ++ + Sbjct: 79 VLQLSGNNPSNFELAYNTLVQMGAGCCFDVVELNMGCPQAVALRGKYGAYLMGHLDLAEE 138 Query: 133 IVKGLRNVLPNK---FSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176 I++ L V ++VK RL K TV +C +L G+ T Sbjct: 139 ILRTLVAVTARSGLGHKVAVKTRLDISDKDTVKMCLRLCSTGIAMFT 185 >UniRef50_A2QES0 Cluster: Contig An02c0390, complete genome; n=12; Pezizomycotina|Rep: Contig An02c0390, complete genome - Aspergillus niger Length = 446 Score = 65.3 bits (152), Expect = 1e-09 Identities = 50/155 (32%), Positives = 77/155 (49%), Gaps = 12/155 (7%) Query: 77 VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136 +I Q + V A+KLV V G+D+N GCP+ ++ G G +LL P+ + I++ Sbjct: 105 LIYQIGTATPEIAVQAAKLVAGDVAGIDVNSGCPKPFSTSGGMGAALLKTPDKLVAILEA 164 Query: 137 L-RNV-LPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHC-TKSSGPVD--- 190 L + V P + ISVKIR+L D ++T L +L K G+T LT HC T P + Sbjct: 165 LVKEVGTPFQIGISVKIRILKDPEETRALVSRLVKTGITGLT---VHCRTPPMRPRERAI 221 Query: 191 ---INGLKEVREALSVPMVANGGVKHLNDATTYMK 222 + + ++ V V NG V ++ MK Sbjct: 222 RDQVRMIADICHEAGVACVINGDVTSKDEGHALMK 256 >UniRef50_Q6MNE9 Cluster: Nitrogen regulation protein nifR3; n=1; Bdellovibrio bacteriovorus|Rep: Nitrogen regulation protein nifR3 - Bdellovibrio bacteriovorus Length = 352 Score = 64.9 bits (151), Expect = 2e-09 Identities = 51/220 (23%), Positives = 99/220 (45%), Gaps = 15/220 (6%) Query: 13 DAKINKTYLKVC-APMVRYSKVHFRTLVRNFNADLCFT----PMILADSFCQNSKARANE 67 D K+N +C APMV + V R ++R++ +T M+ + + + E Sbjct: 11 DGKVN---FPLCLAPMVGLTHVALREVMRDYLPAEAYTIWPTEMLNSRRIPGENLEKTPE 67 Query: 68 FMTTTTDFPVIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSK 126 M + ++ Q N D ++ K + + + +D+N GCP + A+K YG +L+ Sbjct: 68 TMRAAYEPGLVPQILGNEEDAIAESVKRLVEWGAEAIDINMGCPVQKALKHNYGVALMGD 127 Query: 127 PEIIYDIVKGLRNVLPNKFSISVKIRLLNDIK---KTVILCQQLEKCGVTFL-TSMEEHC 182 P ++V+ V + +SVK+R + K + + L + G ++ Sbjct: 128 PAYAAEVVR--MTVKNSTVPVSVKLRAVGSTKEFDELLTFVSGLRQSGAAWVCLHPRTAA 185 Query: 183 TKSSGPVDINGLKEVREALSVPMVANGGVKHLNDATTYMK 222 K G D +K++ +A+ P++ NG V+ +DA +K Sbjct: 186 QKRRGNADWEQIKQLHKAVDFPVIGNGDVQTYDDAINMLK 225 >UniRef50_Q6AKJ6 Cluster: Putative uncharacterized protein; n=1; Desulfotalea psychrophila|Rep: Putative uncharacterized protein - Desulfotalea psychrophila Length = 354 Score = 64.9 bits (151), Expect = 2e-09 Identities = 59/198 (29%), Positives = 90/198 (45%), Gaps = 7/198 (3%) Query: 25 APMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQ-FA 82 APMV S R+L+ + L +T M+ A + A ++ TT + P+I Q F Sbjct: 47 APMVGLSHSALRSLIADLGGCGLFYTEMLAARRLPHENPAVSSYLHTTPCERPLIYQLFI 106 Query: 83 ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 A+ + K+ DGVD+N GCP + G G +L + + DIV R Sbjct: 107 ADVKYVAPALDKIHRLGGDGVDINLGCPAPSVRRGGAGAALAEDWDRVRDIVSSARR--H 164 Query: 143 NKFSISVKIRLLNDIKKTVIL--CQQLEKCGVTFL-TSMEEHCTKSSGPVDINGLKEVRE 199 ++S KIR+ + K+ +L C+ LE GV L H K L + E Sbjct: 165 TDLTLSAKIRVGHVGKEAHLLDFCKMLEAEGVDLLAVHARYHGEKFCRKPRWQLLAPICE 224 Query: 200 ALSVPMVANGGVKHLNDA 217 L +P+ ANGG+ ++DA Sbjct: 225 QLDIPIFANGGIFSVDDA 242 >UniRef50_Q1Q3Q8 Cluster: Strongly similar to tRNA-dihydrouridine synthase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Strongly similar to tRNA-dihydrouridine synthase - Candidatus Kuenenia stuttgartiensis Length = 341 Score = 64.1 bits (149), Expect = 3e-09 Identities = 43/202 (21%), Positives = 86/202 (42%), Gaps = 2/202 (0%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 + APM +S + +R + R F + +T ++ N+K + PV Q Sbjct: 36 ILAPMAGFSDMPYRLICRRFGMSMSYTEVVSVSGIVWNNKKTFKLLDFKEEERPVTFQVV 95 Query: 83 ANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141 N+ +A K + D +D+N GC G G +L P I + L L Sbjct: 96 GNDECQITEACKKIEQLGPDIIDINMGCSVSDIAGKGAGAGMLKHPSKISKMFNNLTGSL 155 Query: 142 PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVREA 200 + +++ + + + + + LE+ G + + ++ SG D + + EV+++ Sbjct: 156 SVPVTGKIRLGWDHKTRNYIEVARILEENGASLIAVHGRTRSQYFSGAADWDAIAEVKQS 215 Query: 201 LSVPMVANGGVKHLNDATTYMK 222 + +P++ANG V+ + D K Sbjct: 216 VKIPVIANGDVRSVADIAEIKK 237 >UniRef50_Q1DPY5 Cluster: Putative uncharacterized protein; n=1; Coccidioides immitis|Rep: Putative uncharacterized protein - Coccidioides immitis Length = 453 Score = 64.1 bits (149), Expect = 3e-09 Identities = 36/102 (35%), Positives = 59/102 (57%), Gaps = 2/102 (1%) Query: 77 VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136 +I Q N V+A+K+V V G+D+N GCP+ ++ G G +LL P+ + I++ Sbjct: 106 LIFQLGTANPSLAVEAAKVVAADVSGIDVNSGCPKPFSTSGGMGAALLQTPDRLVSILEA 165 Query: 137 LRNVL--PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176 L + P + ISVKIRLL + ++T L ++ + G+T LT Sbjct: 166 LVEEIGKPYEIGISVKIRLLAEPERTEALVTRVCRTGITGLT 207 >UniRef50_Q7VKU5 Cluster: tRNA-dihydrouridine synthase C; n=118; Gammaproteobacteria|Rep: tRNA-dihydrouridine synthase C - Haemophilus ducreyi Length = 325 Score = 64.1 bits (149), Expect = 3e-09 Identities = 36/121 (29%), Positives = 60/121 (49%), Gaps = 7/121 (5%) Query: 102 GVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTV 161 G+D NCGCP K G +LL PE+IY K +R +P +SVK+RL D Sbjct: 96 GIDFNCGCPSKTVNGSHGGAALLKDPELIYCATKAIREAVPKAQPVSVKMRLGWDCASQC 155 Query: 162 I-LCQQLEKCGVTFLTSMEEHCTKSSG----PVDINGLKEVREALSVPMVANGGVKHLND 216 + +++ G +T TK G ++ + ++++ L++P++ANG + N Sbjct: 156 FEIADAIQQAGADEITVHGR--TKQDGYRAERINWQAIGQIQQRLNIPVIANGEILDFNS 213 Query: 217 A 217 A Sbjct: 214 A 214 >UniRef50_Q607L4 Cluster: TIM-barrel protein, yjbN family; n=10; Proteobacteria|Rep: TIM-barrel protein, yjbN family - Methylococcus capsulatus Length = 327 Score = 63.7 bits (148), Expect = 3e-09 Identities = 42/191 (21%), Positives = 85/191 (44%), Gaps = 2/191 (1%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 + APM + + FR L R F A L + MI A Q ++ P+ Q Sbjct: 13 ILAPMAGVTDLPFRRLCRQFGAGLAVSEMISASPALQATRKSRLRQDHRGEPGPISVQIV 72 Query: 83 ANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141 + + +A++ D +D+N GCP K G +LL +++ +I++ + + Sbjct: 73 GADPREMAEAARRTVDLGADIIDINMGCPAKKVCNVAAGSALLRDEKLVANILEAVVQAV 132 Query: 142 PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREA 200 P ++ ++ + + V + + E G+ LT +G + + + EV++A Sbjct: 133 PVPVTLKIRTGWDSASRNAVSIGKIAESAGIRALTVHGRTRACGFAGAAEYSTITEVKKA 192 Query: 201 LSVPMVANGGV 211 + +P++ANG + Sbjct: 193 IGIPVIANGDI 203 >UniRef50_Q0G7A4 Cluster: Nitrogen regulation protein nifr3; n=2; Aurantimonadaceae|Rep: Nitrogen regulation protein nifr3 - Fulvimarina pelagi HTCC2506 Length = 344 Score = 63.7 bits (148), Expect = 3e-09 Identities = 49/202 (24%), Positives = 85/202 (42%), Gaps = 8/202 (3%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 AP+ S V FR L R F A L + M+ + F + ++ + D P + Sbjct: 23 APLSGISDVPFRRLSRRFGAGLVVSEMVASGEFVKGAEEGK---LRALRDGPGVHTVQLA 79 Query: 85 NRDDF---VDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG-LRNV 140 RD A +L D +D+N GCP K + G +L+ +P++ + IV+ +R Sbjct: 80 GRDPIWMEEAARRLADEGADLIDINMGCPAKKVVGGLSGSALMREPDLAFSIVEATVRGA 139 Query: 141 LPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE 199 S+ +++ D + + E GVT +T G D + V+ Sbjct: 140 GATPVSLKMRLGWCRDSMNAAEIAVRAEAAGVTMITVHGRTRAEFYEGTADWRAICSVKR 199 Query: 200 ALSVPMVANGGVKHLNDATTYM 221 ++ VP+VANG + N + + Sbjct: 200 SVGVPVVANGDLTEANQLSAIL 221 >UniRef50_Q127F8 Cluster: Dihydrouridine synthase, DuS; n=3; Proteobacteria|Rep: Dihydrouridine synthase, DuS - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 344 Score = 62.9 bits (146), Expect = 6e-09 Identities = 43/150 (28%), Positives = 69/150 (46%), Gaps = 3/150 (2%) Query: 71 TTTDFPVIAQFAANNRDDFVD-ASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129 T PV AQ ++ + A++L G+DLN GCP + G G SLL +PE Sbjct: 65 TLAGVPVRAQLLGSDPACMAENAARLATLGPAGIDLNFGCPAAVVNRHGGGASLLKEPET 124 Query: 130 IYDIVKGLRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGV-TFLTSMEEHCTKSSG 187 + IV +R +P +S K+RL ND + V + + G + Sbjct: 125 LLAIVSAVRRAVPAGMPVSAKMRLGYNDDSRAVECALAIAEGGAGELVVHARTKAQAYKP 184 Query: 188 PVDINGLKEVREALSVPMVANGGVKHLNDA 217 P + ++R A+ +P+VANG + ++DA Sbjct: 185 PAYWERIADIRAAVQIPVVANGEIWTVDDA 214 >UniRef50_Q7R1J1 Cluster: GLP_38_15456_16676; n=1; Giardia lamblia ATCC 50803|Rep: GLP_38_15456_16676 - Giardia lamblia ATCC 50803 Length = 406 Score = 62.9 bits (146), Expect = 6e-09 Identities = 49/172 (28%), Positives = 73/172 (42%), Gaps = 14/172 (8%) Query: 25 APMVRYSKVHFRTLVRNFNAD-------LCFTPMILADSFCQNSKARANEFMTTTTDFPV 77 APM S FR L++ A+ FT M AD+ NS R T + Sbjct: 56 APMTHASGAAFRQLIQGHMAEENERTKYTGFTQMYTADALLHNSPLRDAVLSTAAPGEKI 115 Query: 78 IAQFAANNRDDFVDASKLVY--PYVD---GVDLNCGCPQKWAMKDGYGCSLLSKPEIIYD 132 I Q NN F A++L++ P +D+N GCP A GYG + +++ Sbjct: 116 ILQLCGNNPSTFRAAAELLHDSPIASQLVALDINLGCPASCASSKGYGFYVAQNWPLVHQ 175 Query: 133 IVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTK 184 I+ + F ++ KIR LN I+KT+ L G + +T H T+ Sbjct: 176 IISETSSA--RLFPVTCKIRPLNSIEKTIDYMVLLVMSGASGITIHMRHTTR 225 >UniRef50_Q9CLW3 Cluster: tRNA-dihydrouridine synthase B; n=17; Pasteurellaceae|Rep: tRNA-dihydrouridine synthase B - Pasteurella multocida Length = 332 Score = 62.9 bits (146), Expect = 6e-09 Identities = 44/192 (22%), Positives = 87/192 (45%), Gaps = 8/192 (4%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADS---FCQNSKARANEFMTTTTDFPVIAQF 81 APM + FR + ++ A L F+ M+ + + SK R + Q Sbjct: 15 APMAGITDQPFRRICTHYGAGLTFSEMMSTNPQVWHTEKSKLRLAHHQEAGIN---AVQI 71 Query: 82 AANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140 A + D+ A+++ Y + +D+N GCP K + G +LL P+++ I+ + Sbjct: 72 AGCDPDEMAKAAQINVEYGAEIIDINMGCPAKKVNRKMAGSALLQYPDLVKQILNKVVKS 131 Query: 141 LPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE 199 + ++ ++ D + + + + E+CG+ LT G + + +K V+E Sbjct: 132 VTVPVTLKIRTGWDKDNRNCLEIAKIAEQCGIQALTIHGRTRSCMFEGEAEYDNIKAVKE 191 Query: 200 ALSVPMVANGGV 211 LS+P++ANG + Sbjct: 192 QLSIPIIANGDI 203 >UniRef50_P53720 Cluster: tRNA-dihydrouridine synthase 2; n=7; Saccharomycetales|Rep: tRNA-dihydrouridine synthase 2 - Saccharomyces cerevisiae (Baker's yeast) Length = 384 Score = 62.9 bits (146), Expect = 6e-09 Identities = 43/122 (35%), Positives = 71/122 (58%), Gaps = 12/122 (9%) Query: 100 VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGL-RNV-LPNKFSISVKIRLLNDI 157 V G+D+N GCP+ +++ G G +LL P+ + I+K L +NV P+ ISVKIRLL+ Sbjct: 108 VSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVKIRLLDTK 167 Query: 158 KKTVILCQQLEKCGVTFLTSMEEHCTKS-----SGPVD--INGLKEVREALSVPMVANGG 210 + T+ L ++L G+T LT HC K+ P+ I + E+ +A +V ++ NG Sbjct: 168 QDTLQLVKRLCATGITNLT---VHCRKTEMRNREQPITDYIAEIYEICQANNVSLIVNGA 224 Query: 211 VK 212 ++ Sbjct: 225 IR 226 >UniRef50_Q8XYX1 Cluster: tRNA-dihydrouridine synthase C; n=26; Proteobacteria|Rep: tRNA-dihydrouridine synthase C - Ralstonia solanacearum (Pseudomonas solanacearum) Length = 326 Score = 62.5 bits (145), Expect = 8e-09 Identities = 41/151 (27%), Positives = 76/151 (50%), Gaps = 7/151 (4%) Query: 71 TTTDFPVIAQFAANNRDDFV-DASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129 T + P++ Q ++ + +A++ G+DLN GCP K + G G LL+ PE+ Sbjct: 60 TASGTPMVIQLLGSDPEWLARNAAQAATVSPHGIDLNFGCPAKVVNRHGGGAMLLATPEL 119 Query: 130 IYDIVKGLRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSG- 187 ++ IV +R +P + +++ K+RL ++D + L + G L T+ G Sbjct: 120 LHRIVSTVRAAVPARIAVTAKMRLGVSDTSLAIACATALAEGGAASLVVHAR--TRDHGY 177 Query: 188 --PVDINGLKEVREALSVPMVANGGVKHLND 216 P + + + +A+ VP+VANG V ++D Sbjct: 178 RPPAHWDWIARIADAVRVPVVANGEVWTVDD 208 >UniRef50_O52532 Cluster: tRNA-dihydrouridine synthase B; n=6; Gammaproteobacteria|Rep: tRNA-dihydrouridine synthase B - Serratia marcescens Length = 334 Score = 62.5 bits (145), Expect = 8e-09 Identities = 45/194 (23%), Positives = 91/194 (46%), Gaps = 8/194 (4%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILAD-SFCQNSKARANEFMTTTTDFPVI--A 79 + APM + FRTL A + + M+ ++ + K+R +D P I Sbjct: 13 IAAPMAGITDRPFRTLCHAMGAGMAVSEMLSSNPEVWRTDKSRLR---MVHSDEPGIRSV 69 Query: 80 QFAANNRDDFVDASKL-VYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLR 138 Q A + DD A+++ V +D+N GCP K + G +LL P+++ I+ + Sbjct: 70 QIAGCDPDDMAAAARINVASGAQLIDINMGCPAKKVNRKLAGSALLQYPDLVKRILHAVV 129 Query: 139 NVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEV 197 + + ++ ++ + + V + Q E CG+ LT +G + + ++ V Sbjct: 130 DAVDVPVTLKIRTGWAPEHRNCVEIAQLAEDCGIQALTIHGRTRACLFNGDAEYDSIRAV 189 Query: 198 REALSVPMVANGGV 211 ++++S+P++ANG + Sbjct: 190 KQSVSIPIIANGDI 203 >UniRef50_A3RPJ2 Cluster: TRNA-dihydrouridine synthase; n=2; Proteobacteria|Rep: TRNA-dihydrouridine synthase - Ralstonia solanacearum UW551 Length = 369 Score = 61.7 bits (143), Expect = 1e-08 Identities = 36/114 (31%), Positives = 59/114 (51%), Gaps = 6/114 (5%) Query: 102 GVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRL-LNDIKKT 160 G+DLN GCP K + G G LLS PE+++ IV +R +P +++ K+RL ++D Sbjct: 135 GIDLNFGCPAKVVNRHGGGAMLLSTPELLHTIVSAVRAAVPANIAVTAKMRLGVSDTSLA 194 Query: 161 VILCQQLEKCGVTFLTSMEEHCTKSSG---PVDINGLKEVREALSVPMVANGGV 211 + L + G L T+ G P + + + +A+ VP++ANG V Sbjct: 195 IDCATALAEGGAASLVVHAR--TRDHGYRPPAHWDWIARIADAVEVPVIANGEV 246 >UniRef50_Q4PAE4 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 766 Score = 61.7 bits (143), Expect = 1e-08 Identities = 34/101 (33%), Positives = 56/101 (55%), Gaps = 3/101 (2%) Query: 100 VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKK 159 V VDLNCGCP+ ++ G G ++LS P ++ + +K +R P +++ KIRLL +K Sbjct: 172 VAAVDLNCGCPKPFSTHAGMGANMLSTPILLCNTLKAMRRAAPAHVAVTCKIRLLPTQEK 231 Query: 160 TVILCQQLEKCGVTFLTSMEEHC-TKSSGPVDINGLKEVRE 199 T+ L ++ + G + + HC TK P + L +RE Sbjct: 232 TLELVDKIVRTGA--IECLTVHCRTKDMRPREPALLHRLRE 270 >UniRef50_A7EHJ6 Cluster: Putative uncharacterized protein; n=2; Sclerotiniaceae|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 513 Score = 61.7 bits (143), Expect = 1e-08 Identities = 34/102 (33%), Positives = 60/102 (58%), Gaps = 2/102 (1%) Query: 77 VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136 +I Q ++ + V +++V V G+D+N GCP+ ++ G G +LL P+ + I++ Sbjct: 191 LIFQIGTSDPEKAVQCARMVAADVAGIDVNAGCPKPFSTSGGMGAALLQTPDKLCAILEA 250 Query: 137 L-RNVLPN-KFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176 L + ++P + ISVKIRLL ++T L ++L G+T LT Sbjct: 251 LVKEIVPEFEIGISVKIRLLETPERTEALVRKLCATGITGLT 292 >UniRef50_A6R3V4 Cluster: Putative uncharacterized protein; n=1; Ajellomyces capsulatus NAm1|Rep: Putative uncharacterized protein - Ajellomyces capsulatus NAm1 Length = 461 Score = 61.7 bits (143), Expect = 1e-08 Identities = 36/102 (35%), Positives = 57/102 (55%), Gaps = 2/102 (1%) Query: 77 VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136 ++ Q + D V A+K++ V G+D+N GCP+ ++ G G +LL P+ + I+ Sbjct: 88 LVFQIGTASPDLAVQAAKIIAADVAGIDVNAGCPKPFSTTGGMGAALLQTPDRLVSILTA 147 Query: 137 LRNVL--PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176 L + P + ISVKIRLL D ++T L +L G+T LT Sbjct: 148 LVQQVGTPYQIGISVKIRLLADPERTRDLVTRLCATGITGLT 189 >UniRef50_Q08111 Cluster: Probable tRNA-dihydrouridine synthase; n=21; Alphaproteobacteria|Rep: Probable tRNA-dihydrouridine synthase - Rhodobacter capsulatus (Rhodopseudomonas capsulata) Length = 324 Score = 61.7 bits (143), Expect = 1e-08 Identities = 44/190 (23%), Positives = 78/190 (41%), Gaps = 3/190 (1%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILA-DSFCQNSKARANEFMTTTTDFPVIAQFAA 83 APM + + FR +V F A L + M+ + + RA T P Q A Sbjct: 17 APMAGITDLPFRRMVARFGAGLVVSEMVASGEMLTAKPSVRAKAQAELTAGLPTSVQLAG 76 Query: 84 NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 +A+K+V + +D+N GCP K G +L+ P+ +++ + + Sbjct: 77 REAAPMAEAAKIVADMGAEIIDINMGCPAKKVTGGLSGAALMRNPDHALRLIEAVVGAVD 136 Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM-EEHCTKSSGPVDINGLKEVREAL 201 ++ +++ D + + E GV + +G D + VR A+ Sbjct: 137 LPVTLKMRLGWDEDQLNAAEIAARAEAAGVKMIVIHGRTRMQFYTGAADWRAIAAVRAAV 196 Query: 202 SVPMVANGGV 211 SVP+VANG + Sbjct: 197 SVPVVANGDI 206 >UniRef50_Q3AZ67 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3; n=20; Cyanobacteria|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 - Synechococcus sp. (strain CC9902) Length = 356 Score = 61.3 bits (142), Expect = 2e-08 Identities = 45/196 (22%), Positives = 84/196 (42%), Gaps = 4/196 (2%) Query: 25 APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83 +P+ + FR LVR ++ D L FT M+ A S + + P+ Q Sbjct: 42 SPLAGVTDKIFRGLVRRWSRDSLLFTEMVNATSL-ELGHGYGKMDDLKAEEGPIAVQLFD 100 Query: 84 NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 + A++ +D+N GCP + K G G L+ P + I++ + + + Sbjct: 101 HRPHAMAHAARRAEQAGAFLIDINMGCPVRKIAKKGGGSGLIRDPNLATQILEAVVDAVS 160 Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVREAL 201 ++ ++ + C+QL+ G LT + G + N + EV++AL Sbjct: 161 IPVTVKTRLGWCGSSSDPITWCRQLQNAGAQMLTLHGRTREQGFKGQANWNAIAEVKQAL 220 Query: 202 SVPMVANGGVKHLNDA 217 ++P++ANG + DA Sbjct: 221 TIPVIANGDINSPTDA 236 >UniRef50_Q2RM54 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3; n=1; Moorella thermoacetica ATCC 39073|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 - Moorella thermoacetica (strain ATCC 39073) Length = 334 Score = 61.3 bits (142), Expect = 2e-08 Identities = 51/202 (25%), Positives = 84/202 (41%), Gaps = 3/202 (1%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 + APM Y+ FR L R A L +T MI A N+K PV Q Sbjct: 17 IMAPMAGYTDRVFRLLAREAGAALTYTEMISAQGLIYNNKNTHALLDLKGEPGPVAVQLF 76 Query: 83 ANNRDDFVDASKL-VYPYVDGVDLNCGCPQKWAMKDGYGCSLLSK-PEIIYDIVKGLRNV 140 + A+++ V +DLN GCP +K+G G +L+ P + +R Sbjct: 77 GREPEIMAAATRIAVAAGAAIIDLNMGCPTPKIVKNGEGSALMRDLPRAAAIVAAMVRAA 136 Query: 141 LPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVRE 199 P ++ +++ D V + + G + ++ SG D + + V+E Sbjct: 137 GPVPVTVKMRLGWDEDSINVVEAARAVVYAGAAAVAIHGRTRSQFYSGRADWSYFRRVKE 196 Query: 200 ALSVPMVANGGVKHLNDATTYM 221 A+ VP++ NG V+ DA T + Sbjct: 197 AVDVPVIGNGDVRTARDAVTML 218 >UniRef50_Q22A31 Cluster: TIM-barrel protein, yjbN family; n=1; Tetrahymena thermophila SB210|Rep: TIM-barrel protein, yjbN family - Tetrahymena thermophila SB210 Length = 480 Score = 61.3 bits (142), Expect = 2e-08 Identities = 39/142 (27%), Positives = 65/142 (45%), Gaps = 5/142 (3%) Query: 14 AKINKTYLKVCAPMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQNSKARANEFMTTT 72 A IN + V APM+ + VHFR +R + +T MI + N + Sbjct: 97 ANINYHTIAV-APMIDITDVHFRNFIRLLTRYSILYTEMIHEQAVHHNIRGPQEFLRFDP 155 Query: 73 TDFPVIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIY 131 PV+ Q N+ D+ A+K+ D V+LN GCP +G L+ +PE++ Sbjct: 156 VQHPVVIQLGGNDPDNLAKAAKICEEIGYDEVNLNVGCPSDRVQSGKFGACLMKEPELVA 215 Query: 132 DIVKGLRNVLPNKFSISVKIRL 153 +I++ ++ ++VK RL Sbjct: 216 EIMRKMKEAC--SIPVTVKCRL 235 >UniRef50_O25427 Cluster: Probable tRNA-dihydrouridine synthase; n=9; Epsilonproteobacteria|Rep: Probable tRNA-dihydrouridine synthase - Helicobacter pylori (Campylobacter pylori) Length = 328 Score = 61.3 bits (142), Expect = 2e-08 Identities = 46/205 (22%), Positives = 89/205 (43%), Gaps = 6/205 (2%) Query: 17 NKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP 76 NK +L + AP+ Y+ + FR++V+ F D+ + M+ + S + + + Sbjct: 5 NKKWLFL-APLAGYTDLPFRSVVKKFGVDVTTSEMVSSHSLVYAFDKTSKMLEKSPLEDH 63 Query: 77 VIAQFAANNRDDFVDASKLV--YPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134 +AQ + + +A + + +V+G+D NCGCP G G LL + ++ Sbjct: 64 FMAQISGSKESVVKEAVEKINALEHVNGIDFNCGCPAPKVANHGNGSGLLKDLNHLVKLL 123 Query: 135 KGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT--SMEEHCTKSSGPVDIN 192 K +R K + SVK+RL + K + L V ++ +D Sbjct: 124 KTIRENTSKKIT-SVKVRLGFEKKIPKEIAHALNDAPVDYVVVHGRTRSDKYQKDKIDYE 182 Query: 193 GLKEVREALSVPMVANGGVKHLNDA 217 + +++ L P++ANG + + A Sbjct: 183 SIALMKKILKKPVIANGEIDSVKKA 207 >UniRef50_Q8YAB9 Cluster: Lmo0227 protein; n=55; Bacteria|Rep: Lmo0227 protein - Listeria monocytogenes Length = 331 Score = 60.9 bits (141), Expect = 2e-08 Identities = 46/198 (23%), Positives = 79/198 (39%), Gaps = 3/198 (1%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 V APM S FR V+ F A L MI + + + P+ Q Sbjct: 14 VVAPMAGISNSAFRLTVKEFGAGLVCCEMISDKGIAYRNAKTLDMLYIDEKEKPLSLQIF 73 Query: 83 ANNRDDFVDASKLVYPYV--DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140 ++ V+A+K V D +D+N GCP +K G L P +YD+V + + Sbjct: 74 GGEKETLVEAAKFVAENTTADIIDINMGCPVNKIIKCEAGAKWLLDPNKVYDMVAAVVDA 133 Query: 141 LPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM-EEHCTKSSGPVDINGLKEVRE 199 + ++ ++I + + E+ G + G + + L++V+ Sbjct: 134 VDKPVTVKMRIGWDEEHVFAIENALAAERAGAAAVAMHGRTRVQMYEGSANWDVLRDVKR 193 Query: 200 ALSVPMVANGGVKHLNDA 217 L +P +ANG V+ DA Sbjct: 194 ELKIPFMANGDVRTPEDA 211 >UniRef50_Q7XWZ9 Cluster: OSJNBa0079F16.4 protein; n=8; Oryza sativa|Rep: OSJNBa0079F16.4 protein - Oryza sativa (Rice) Length = 1708 Score = 60.9 bits (141), Expect = 2e-08 Identities = 42/150 (28%), Positives = 76/150 (50%), Gaps = 8/150 (5%) Query: 25 APMVRYSKVHFRTLVRNFNADL-CFTPMILADSFCQNSKARANEFMTTTTD-FPVIAQFA 82 APM+ ++ H+RTL R + +T M++A++ + K + F+ + P++ Q Sbjct: 68 APMMDWTDNHYRTLARLISKHAWLYTEMVVAETIV-HQKDNLDRFLAFPAEQHPIVLQIG 126 Query: 83 ANNRDDFVDASKLVYPY-VDGVDLNCGCPQ-KWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140 +N D+ A++L Y D ++LNCGCP K A +G L+ PE + D + + Sbjct: 127 GSNLDNLAKATELANAYSYDEINLNCGCPSGKVAGHGCFGARLMFDPEFVGDAMSAI--A 184 Query: 141 LPNKFSISVKIRL-LNDIKKTVILCQQLEK 169 +SVK R+ ++D LC+ ++K Sbjct: 185 ANCNVPVSVKCRIGVDDRDSYEELCEFVDK 214 >UniRef50_Q6PEH0 Cluster: Zgc:63779; n=8; Chordata|Rep: Zgc:63779 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 660 Score = 60.5 bits (140), Expect = 3e-08 Identities = 51/207 (24%), Positives = 89/207 (42%), Gaps = 11/207 (5%) Query: 17 NKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP 76 +K YL AP+ + FR + + F AD+ M + + Q + ++ Sbjct: 315 DKLYL---APLTTCGNLPFRRVCKRFGADITCGEMAMCTNLLQGQASEWALLKRHASEDL 371 Query: 77 VIAQFAANNRDDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134 Q D ++L+ VD VD+N GCP K G GC L+++ IV Sbjct: 372 FGVQLEGCFPDTMTRCAELLNQNIDVDFVDINSGCPIDLVYKKGGGCGLMTRTSKFEQIV 431 Query: 135 KGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT----SMEEHCTKSSGPVD 190 +G+ +VL ++ ++ + + L +++K GV+ +T S E+ TK + Sbjct: 432 RGMNSVLDVPLTVKIRTGVQQNSNIAHKLIPEMKKWGVSLITLHGRSREQRYTKLADWDY 491 Query: 191 INGLKEVREALSVPMVANGGVKHLNDA 217 IN ++ A VP+ NG + DA Sbjct: 492 INTCAQL--AAPVPLFGNGDILSYEDA 516 >UniRef50_A4SY29 Cluster: Dihydrouridine synthase, DuS; n=1; Polynucleobacter sp. QLW-P1DMWA-1|Rep: Dihydrouridine synthase, DuS - Polynucleobacter sp. QLW-P1DMWA-1 Length = 347 Score = 59.3 bits (137), Expect = 7e-08 Identities = 33/129 (25%), Positives = 65/129 (50%), Gaps = 6/129 (4%) Query: 27 MVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAANN 85 M+ ++ H R+ R + + +T M+ + R ++ + PV+ Q + Sbjct: 1 MMEWTDRHCRSFHRALTTEAVLYTEMVTTGALMHGDVPRHLDY--SQDQHPVVLQLGGSE 58 Query: 86 RDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNK 144 +D +++L + D +DLNCGCP + + +G L+++P+++ D VK ++N + Sbjct: 59 PNDLARSAELAQQWGYDEIDLNCGCPSERVQRGAFGACLMAEPKLVADCVKAMQNAV--D 116 Query: 145 FSISVKIRL 153 ISVK RL Sbjct: 117 IPISVKHRL 125 >UniRef50_A6U9Y2 Cluster: Dihydrouridine synthase DuS; n=2; Sinorhizobium|Rep: Dihydrouridine synthase DuS - Sinorhizobium medicae WSM419 Length = 385 Score = 58.8 bits (136), Expect = 1e-07 Identities = 35/148 (23%), Positives = 72/148 (48%), Gaps = 6/148 (4%) Query: 25 APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83 APM+ ++ H+R R + L +T MI+AD+ + +A+ ++ PV Q Sbjct: 25 APMIDWTDRHYRFFARVLSRHALLYTEMIVADAVLRGDRAKL--LGHDASEHPVALQLGG 82 Query: 84 NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 N+ +A+++ Y D +++N GCP +G L+ +P ++ D + ++ + Sbjct: 83 NDPVKMAEAARIGEAYGYDEINMNVGCPSDRVQSGTFGACLMQEPALVADCIAAMKAAV- 141 Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKC 170 + ++VK R+ D + + + L KC Sbjct: 142 -EIPVTVKCRIGVDDQDPEVALRDLVKC 168 >UniRef50_A4S604 Cluster: Predicted protein; n=1; Ostreococcus lucimarinus CCE9901|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 287 Score = 58.8 bits (136), Expect = 1e-07 Identities = 53/208 (25%), Positives = 97/208 (46%), Gaps = 15/208 (7%) Query: 25 APMVRYSKVHFRTLVRN-FNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVI--AQF 81 AP+ + FR L + F A++ + M A + ++ D AQ Sbjct: 7 APLTKGGNAPFRRLCASEFGAEVVVSEMAFARFLAKGARVERARVRRHEGDAGDCFGAQI 66 Query: 82 AANNRDDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139 A N ++ V+A+ + D VDLNCGCP K G G +LL KP + +V+G+ + Sbjct: 67 ATNAIEEGVNAALIASGEFGADFVDLNCGCPIHETWKRGLGAALLKKPAKLERLVEGIAS 126 Query: 140 VLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLT----SMEEHCTKSSGPVDINGL 194 + ++VKIRL ++ + + + LE G + + + E+ TK++ D + + Sbjct: 127 RI--DVPLTVKIRLGIDSSSQARRIAEGLENAGASAVVVHGRTKEQRYTKAA---DYDVI 181 Query: 195 KEVREALSVPMVANGGVKHLNDATTYMK 222 +++ ++P++ NG V DA M+ Sbjct: 182 RDIVRERNIPIIGNGDVLTWYDARDRME 209 >UniRef50_Q54CU9 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 671 Score = 58.8 bits (136), Expect = 1e-07 Identities = 42/205 (20%), Positives = 84/205 (40%), Gaps = 3/205 (1%) Query: 15 KINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTD 74 +IN + AP+ + FR + + AD+ M L + +K+ + Sbjct: 319 RINFENQLILAPLTTVGNLPFRRICKRLGADITIGEMALTTKLLEGTKSELALLKRHPCE 378 Query: 75 FPVIAQFAANNRDDFVDASKLVYPYVDG--VDLNCGCPQKWAMKDGYGCSLLSKPEIIYD 132 Q + D V ++ + +D VD+N GCP G G +L+ +P+ + Sbjct: 379 DKFGVQICGSYVDAAVKCAEFIENEIDADFVDINSGCPIDLVCNMGAGAALMERPKKVEQ 438 Query: 133 IVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDI 191 +++G+ + L +I ++I D L L + G +T + S + Sbjct: 439 LLRGISSSLSCPTTIKIRIGKSEDAPTAHKLIPSLGEWGACAVTLHGRSRAQRYSRLANW 498 Query: 192 NGLKEVREALSVPMVANGGVKHLND 216 + +K+ E S+P++ NG + + D Sbjct: 499 DYVKQCSEVSSIPLIGNGDIYNYQD 523 >UniRef50_A7CWF1 Cluster: Putative TIM-barrel protein, nifR3 family; n=1; Opitutaceae bacterium TAV2|Rep: Putative TIM-barrel protein, nifR3 family - Opitutaceae bacterium TAV2 Length = 389 Score = 58.4 bits (135), Expect = 1e-07 Identities = 49/193 (25%), Positives = 86/193 (44%), Gaps = 6/193 (3%) Query: 25 APMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83 +P+ Y+ + R VR T ++ A S + SK T D P+ Q Sbjct: 15 SPLAGYTNLPMRLTVRELGGLGWATTDLVNARSLIERSKGAMKLVETAPGDQPLAIQLFG 74 Query: 84 NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 + ++ DA+ + VD+N GCP K + G G +++++ +V+G+ + Sbjct: 75 SVPEEMRDAAVICKELGAQSVDVNMGCPVKKVVGIGGGAAMMTELNKTAALVRGMVEAVG 134 Query: 143 NKFSISVKIRL-LNDIKKTV-ILCQQLEKCGV-TFLTSMEEHCTKSSGPVDINGLKEVRE 199 NK ++ K+RL +D T L + L GV SG V++ G++ V E Sbjct: 135 NKIPVTAKMRLGWDDANITAPDLARVLADVGVAAIFVHGRTRAQGFSGTVNLAGIRAVVE 194 Query: 200 AL-SVPMVANGGV 211 A+ +P++ NG V Sbjct: 195 AVPGLPVIGNGDV 207 >UniRef50_Q9TYN2 Cluster: Putative uncharacterized protein Y37E11B.5; n=2; Caenorhabditis|Rep: Putative uncharacterized protein Y37E11B.5 - Caenorhabditis elegans Length = 554 Score = 58.4 bits (135), Expect = 1e-07 Identities = 36/133 (27%), Positives = 63/133 (47%), Gaps = 2/133 (1%) Query: 22 KVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQF 81 K AP+ + FR + ++ AD+ M LA S + + + + Q Sbjct: 206 KYLAPLTTVGNLPFRRICVDYGADITCGEMALATSILSGTASEYSLLKRHPCEKIFGVQL 265 Query: 82 AANNRDDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139 A D AS++V VD +D+N GCP + G GC+L S+P+ +++++ ++ Sbjct: 266 AGGFADTMAKASQIVVENFDVDFIDINMGCPIDVVNQKGGGCALPSRPQKLFEVLAATKS 325 Query: 140 VLPNKFSISVKIR 152 VL ++VKIR Sbjct: 326 VLGGCCPLTVKIR 338 >UniRef50_Q9ZED2 Cluster: Probable tRNA-dihydrouridine synthase; n=39; Proteobacteria|Rep: Probable tRNA-dihydrouridine synthase - Rickettsia prowazekii Length = 327 Score = 58.4 bits (135), Expect = 1e-07 Identities = 47/199 (23%), Positives = 89/199 (44%), Gaps = 5/199 (2%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIA--Q 80 + APM + + FR LV+ F A L + MI + + S+ ++ + D P A Q Sbjct: 14 ILAPMSDVTDLEFRKLVKRFGAGLVVSEMIASRAMIMKSR-QSMQKCAIMHDDPTSACVQ 72 Query: 81 FAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139 A D +A+K+ +DLN GCP K + G +L+ ++ I + Sbjct: 73 LAGCEPDVIAEAAKMNEDMGAKIIDLNFGCPAKKVVGGYAGSALMRDEQLAAKIFEATVK 132 Query: 140 VLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM-EEHCTKSSGPVDINGLKEVR 198 + ++ ++I ++ + L + GV +T C SG + + ++ V+ Sbjct: 133 AVKIPVTVKMRIGWDDNTRNAPTLAKIAANSGVQMVTVHGRTRCQFYSGNANWDFIRTVK 192 Query: 199 EALSVPMVANGGVKHLNDA 217 EA+ +P++ANG + + A Sbjct: 193 EAVKIPVIANGDITNFAKA 211 >UniRef50_Q9RRP8 Cluster: NifR3 protein; n=2; Deinococcus|Rep: NifR3 protein - Deinococcus radiodurans Length = 406 Score = 58.0 bits (134), Expect = 2e-07 Identities = 53/196 (27%), Positives = 81/196 (41%), Gaps = 13/196 (6%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPV----I 78 V APM YS R L A + MI A S+ E ++ +P Sbjct: 95 VLAPMAGYSDAPMRQLAAEQGALWTVSEMISARGLVLGSE---QESLSLGRPYPGEQGRA 151 Query: 79 AQFAANNRDDFVDASKLVYPYVD--GVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136 Q + D DA + +DLN GCP G C LL PE+ Y++V+ Sbjct: 152 VQLFGADPDVLADAVGKAEAWFAPAAIDLNLGCPVPKVRGKGGAC-LLQTPEVAYELVRA 210 Query: 137 LRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLK 195 +R +S KIRL D ++V + Q LE G +T + +G D + + Sbjct: 211 MRQA--TGLDVSAKIRLGWDENRSVEIAQGLEAAGAAVVTVHGRTSAQRYTGNADWDAIG 268 Query: 196 EVREALSVPMVANGGV 211 V +A+ +P++ +G V Sbjct: 269 RVAQAVRIPVIGSGDV 284 >UniRef50_Q3IKP0 Cluster: TRNA-dihydrouridine synthase C; n=5; Alteromonadales|Rep: TRNA-dihydrouridine synthase C - Pseudoalteromonas haloplanktis (strain TAC 125) Length = 326 Score = 58.0 bits (134), Expect = 2e-07 Identities = 58/213 (27%), Positives = 86/213 (40%), Gaps = 16/213 (7%) Query: 23 VCAPMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQNSKA------RANEFMTTTTDF 75 V APM R L+ N DLC T + C K + T+ Sbjct: 4 VLAPMEGVVDFKMRQLLTNVGGFDLCVTEFVRVVDACLPDKVFYRYCPELSNNGLTSAGT 63 Query: 76 PVIAQFAANNRDDFVD-ASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134 PV Q + A K + G+DLN GCP K K G LL PE +Y+I+ Sbjct: 64 PVRIQLLGQVAGALAENAVKAISLGSHGIDLNFGCPAKTVNKSKGGAVLLKDPEHMYEII 123 Query: 135 KGLRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHC-TKSSG---PV 189 K +R+ + +K +S KIRL +D + + + G +S+ H TK G P Sbjct: 124 KAVRDAVDSKHQVSAKIRLGFDDDSNSQEIVDAVVSAGA---SSIAIHARTKRDGYNPPA 180 Query: 190 DINGLKEVREALSVPMVANGGVKHLNDATTYMK 222 + + + + +VANG + + DA K Sbjct: 181 YWEKIPPLIKDKDIAVVANGEIWQVADAMLCQK 213 >UniRef50_A1VHK2 Cluster: Dihydrouridine synthase, DuS; n=4; Desulfovibrionaceae|Rep: Dihydrouridine synthase, DuS - Desulfovibrio vulgaris subsp. vulgaris (strain DP4) Length = 449 Score = 58.0 bits (134), Expect = 2e-07 Identities = 54/190 (28%), Positives = 84/190 (44%), Gaps = 7/190 (3%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 AP+ YS + FR L R A +C T M+ A S + TT D P++ Q Sbjct: 37 APLAGYSDLSFRLLCRKAGAAVCCTEMVSAKGLIYYSPGTRDLLATTPEDAPLVVQLFGC 96 Query: 85 NRDDFVDASK-LVYPYVDGVDLNCGCPQKWAMKDGYGCSLL-SKPEIIYDIVKGLRNVLP 142 + D V A + L+ DLN GC +K G G ++L P+ + LR Sbjct: 97 DPDIMVRAMEPLLEQGFRWFDLNMGCSVPKVVKTGCGAAMLRDVPQALAVARAMLRTAGA 156 Query: 143 NKFSISVKIRLLNDIKKTV--ILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVRE 199 + + K RL D+ + V L + L G ++T + + SG + L E+ Sbjct: 157 GR--VGFKFRLGWDVGQEVWADLGRALADLGAGWVTLHPRYARQGFSGEARWSTLGELVR 214 Query: 200 ALSVPMVANG 209 A+SVP++A+G Sbjct: 215 AVSVPVIASG 224 >UniRef50_Q5SMC7 Cluster: TRNA-dihydrouridine synthase; n=2; Thermus thermophilus|Rep: TRNA-dihydrouridine synthase - Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) Length = 342 Score = 57.6 bits (133), Expect = 2e-07 Identities = 52/213 (24%), Positives = 103/213 (48%), Gaps = 19/213 (8%) Query: 25 APMVRYSKVHFRTLVRNFNADL-CFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83 APMV + HFR LVR + + +T M + + + ++ R F + P+ Q A Sbjct: 9 APMVDRTDRHFRFLVRQVSLGVRLYTEMTVDQAVLRGNRERLLAFRPE--EHPIALQLAG 66 Query: 84 NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 ++ +A+++ + D ++LN GCP + A + GYG LL + +I+K + + Sbjct: 67 SDPKSLAEAARIGEAFGYDEINLNLGCPSEKAQEGGYGACLLLDLARVREILKAMGEAV- 125 Query: 143 NKFSISVKIRLLNDIKKTVI-LCQQLE---KCGV--------TFLTSMEEHCTKSSGPVD 190 + ++VK+RL + K+T L Q +E + GV + L ++ + P+ Sbjct: 126 -RVPVTVKMRLGLEGKETYRGLAQSVEAMAEAGVKVFVVHARSALLALSTKANREIPPLR 184 Query: 191 INGLKEVR-EALSVPMVANGGVKHLNDATTYMK 222 + + ++ + + V NGG++ L +A ++K Sbjct: 185 HDWVHRLKGDFPQLTFVTNGGIRSLEEALFHLK 217 >UniRef50_Q5LQV9 Cluster: TRNA-dihydrouridine synthase A; n=46; Bacteria|Rep: TRNA-dihydrouridine synthase A - Silicibacter pomeroyi Length = 344 Score = 57.6 bits (133), Expect = 2e-07 Identities = 34/141 (24%), Positives = 67/141 (47%), Gaps = 4/141 (2%) Query: 24 CAPMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 CAPM+ ++ H R L R + L +T M+ A + + E+ + + PV Q Sbjct: 15 CAPMMDWTDRHCRYLHRLLSRQTLLYTEMVTAPALVRGGALHLLEY--SVEEHPVALQLG 72 Query: 83 ANNRDDFVDASKL-VYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141 ++ ++ A++L D ++LNCGCP +G L+ P ++ D V +R + Sbjct: 73 GSDPEELAQAARLGAEAGYDEINLNCGCPSDRVQSGTFGAVLMKHPGLVADCVTAMREAV 132 Query: 142 PNKFSISVKIRLLNDIKKTVI 162 + ++ +I + + +TV+ Sbjct: 133 DVEVTVKCRIGVDDQDPETVL 153 >UniRef50_Q4FQ57 Cluster: Possible tRNA-dihydrouridine synthase; n=5; Moraxellaceae|Rep: Possible tRNA-dihydrouridine synthase - Psychrobacter arcticum Length = 350 Score = 57.6 bits (133), Expect = 2e-07 Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 1/120 (0%) Query: 103 VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRL-LNDIKKTV 161 +D+N GCP K G LL +PE++YDI+ +R +P +S KIRL D + Sbjct: 127 IDINFGCPAKTVNSHRGGSVLLDEPEVMYDIISAVRQAVPANIPVSAKIRLGYTDTSRMD 186 Query: 162 ILCQQLEKCGVTFLTSMEEHCTKSSGPVDINGLKEVREALSVPMVANGGVKHLNDATTYM 221 + + G +LT T+ P + +L +P++ANG + + A M Sbjct: 187 DIRGAIAASGADWLTIHARTKTQGYKPPAYWDKIQAFNSLKIPVIANGEIWNSEHAQNCM 246 >UniRef50_Q1QZQ6 Cluster: Dihydrouridine synthase, DuS; n=1; Chromohalobacter salexigens DSM 3043|Rep: Dihydrouridine synthase, DuS - Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768) Length = 340 Score = 57.6 bits (133), Expect = 2e-07 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 5/118 (4%) Query: 103 VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL-PNKFSISVKIRLLNDIKKTV 161 VDLN GCP K + G SLL +PE ++ +V+ + L P +++ KIRL D K Sbjct: 99 VDLNFGCPAKTVNRHDGGASLLRQPERVHTVVRAVAEALAPLGIAVTAKIRLGFDDKHVA 158 Query: 162 ILCQQLEKCGVTFLTSMEEHCTKSSG---PVDINGLKEVREALSVPMVANGGVKHLND 216 + C + + G + T+ G P + ++ LS+P++ANG + L D Sbjct: 159 LACAEAAESGGAAHLVVHAR-TRREGYRPPAHWEWIGRIQARLSIPVIANGDIWTLED 215 >UniRef50_A6W1E8 Cluster: Dihydrouridine synthase DuS; n=1; Marinomonas sp. MWYL1|Rep: Dihydrouridine synthase DuS - Marinomonas sp. MWYL1 Length = 335 Score = 57.6 bits (133), Expect = 2e-07 Identities = 43/146 (29%), Positives = 65/146 (44%), Gaps = 7/146 (4%) Query: 71 TTTDFPVIAQFAANNRDDFVDAS-KLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129 TT + PV Q +N + +++ +D+N GCP K G G LL P+ Sbjct: 77 TTHNHPVHTQLLGSNAELMAESALNATKAGAKHIDVNFGCPAKRVNGHGGGSVLLQTPDA 136 Query: 130 IYDIVKGLRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSG- 187 +YDI+ +R+ LP+ +S KIRL D +E GV LT TK G Sbjct: 137 LYDIMSAIRDTLPSDIPVSAKIRLGFEDEALLFDNVAAIEAAGVGTLTIHGR--TKKDGY 194 Query: 188 --PVDINGLKEVREALSVPMVANGGV 211 P + E++ + +VANG + Sbjct: 195 KPPARWEKIGEIQAKTKMTVVANGDI 220 >UniRef50_Q96G46 Cluster: tRNA-dihydrouridine synthase 3-like; n=12; Eutheria|Rep: tRNA-dihydrouridine synthase 3-like - Homo sapiens (Human) Length = 650 Score = 57.6 bits (133), Expect = 2e-07 Identities = 49/205 (23%), Positives = 85/205 (41%), Gaps = 10/205 (4%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 AP+ + FR + + F AD+ M + + Q + + Q Sbjct: 310 APLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALLKRHQCEDIFGVQLEGA 369 Query: 85 NRDDFVDASKLVYPYV--DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 D ++L+ V D VD+N GCP K G GC+L+++ IV+G+ VL Sbjct: 370 FPDTMTKCAELLSRTVEVDFVDINVGCPIDLVYKKGGGCALMNRSTKFQQIVRGMNQVLD 429 Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT----SMEEHCTKSSGPVDINGLKE-V 197 ++ ++ + + L +L GV +T S E+ TK + D ++E V Sbjct: 430 VPLTVKIRTGVQERVNLAHRLLPELRDWGVALVTLHGRSREQRYTKLA---DWQYIEECV 486 Query: 198 REALSVPMVANGGVKHLNDATTYMK 222 + A +P+ NG + DA M+ Sbjct: 487 QAASPMPLFGNGDILSFEDANRAMQ 511 >UniRef50_Q8GQD1 Cluster: NifR; n=5; Leptospira|Rep: NifR - Leptospira interrogans Length = 329 Score = 57.2 bits (132), Expect = 3e-07 Identities = 41/195 (21%), Positives = 82/195 (42%), Gaps = 2/195 (1%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 +PM S R + R F A +T + D + F + P+ Q N Sbjct: 16 SPMAGISDSPTRRICRKFGAAFSYTEFVNTDELVHRAPKALKMFRYKLEERPITFQIFGN 75 Query: 85 NRDDFVDASKLVYPYV-DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143 + +A++++ D +DLN GC + G G LL +P + I++ ++ + Sbjct: 76 RLEIIAEAAEIIQELKPDIIDLNMGCSTRKVSLRGAGAGLLRRPLLAGKIIEAIKKRVNI 135 Query: 144 KFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVREALS 202 + ++I + + + + + LE+ GV LT + +G D + + E++ Sbjct: 136 PVTAKIRIGWDSTSRNYLEVSKILEESGVDALTVHGRTKEMAYTGFADWDAIGEIKVNRK 195 Query: 203 VPMVANGGVKHLNDA 217 +P+ NG +K +A Sbjct: 196 IPIFGNGDIKSFQEA 210 >UniRef50_A3JG66 Cluster: Putative uncharacterized protein; n=3; Gammaproteobacteria|Rep: Putative uncharacterized protein - Marinobacter sp. ELB17 Length = 335 Score = 57.2 bits (132), Expect = 3e-07 Identities = 32/111 (28%), Positives = 54/111 (48%), Gaps = 2/111 (1%) Query: 103 VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVI 162 VD+N GCP K K GC L+ +PE++++I +R +P ++ K+RL D + + Sbjct: 92 VDINFGCPAKTVNKHKGGCVLMREPELMHEITAAVRQAVPADILVTAKMRLGYDDRSMGV 151 Query: 163 LC-QQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVREALSVPMVANGGV 211 C Q L+ G + T P + + REA+ ++ANG + Sbjct: 152 ACAQALDAAGAGEIVIHARSKTDGYKPPAYWEEIAKAREAVKAKVIANGDI 202 >UniRef50_A5D5Q0 Cluster: TRNA-dihydrouridine synthase; n=5; Firmicutes|Rep: TRNA-dihydrouridine synthase - Pelotomaculum thermopropionicum SI Length = 324 Score = 56.8 bits (131), Expect = 4e-07 Identities = 50/204 (24%), Positives = 85/204 (41%), Gaps = 6/204 (2%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 + APM + FR L R F L T M+ + + + PV Q Sbjct: 13 IAAPMAGITDKAFRILAREFGCGLVCTEMVSDQALLHGNPKTCSLLDVAGEAGPVSVQIF 72 Query: 83 ANNRDDFVDASKLVYPYVDGV-DLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141 +N +A+ + G+ D+N GCP +K+G G +L+ +PE IV+ + V Sbjct: 73 GSNAACMAEAAGIAESRGAGIIDINMGCPTPKIVKNGEGAALMREPEKAARIVRAV--VE 130 Query: 142 PNKFSISVKIR--LLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVR 198 K ++VK+R ++ V L + + G +T +G D + V+ Sbjct: 131 RVKVPVTVKMRKGWDDNSPNAVELARLAAEAGAAAVTVHGRTRSQLYAGKADWEIIAAVK 190 Query: 199 EALSVPMVANGGVKHLNDATTYMK 222 A+ VP++ NG V DA ++ Sbjct: 191 RAVDVPVIGNGDVWTPQDALAMLE 214 >UniRef50_Q9LY64 Cluster: Putative uncharacterized protein MAA21_140; n=4; Arabidopsis thaliana|Rep: Putative uncharacterized protein MAA21_140 - Arabidopsis thaliana (Mouse-ear cress) Length = 456 Score = 56.8 bits (131), Expect = 4e-07 Identities = 35/111 (31%), Positives = 59/111 (53%), Gaps = 5/111 (4%) Query: 25 APMVRYSKVHFRTLVRNFNADL-CFTPMILADSFCQNSKARANEFMT-TTTDFPVIAQFA 82 APM+ ++ H+RTL R +T MI A++ + + + F+ + P++ Q Sbjct: 42 APMMDWTDNHYRTLARLITKHAWLYTEMIAAETLV-HQQTNLDRFLAFSPQQHPIVLQLG 100 Query: 83 ANNRDDFVDASKLVYPY-VDGVDLNCGCPQ-KWAMKDGYGCSLLSKPEIIY 131 +N ++ A+KL Y D ++LNCGCP K A +G SL+ KP++ Y Sbjct: 101 GSNVENLAKAAKLSDAYGYDEINLNCGCPSPKVAGHGCFGVSLMLKPKVRY 151 >UniRef50_Q9Z7D8 Cluster: Predicted oxidoreductase; n=7; Chlamydiaceae|Rep: Predicted oxidoreductase - Chlamydia pneumoniae (Chlamydophila pneumoniae) Length = 335 Score = 56.0 bits (129), Expect = 7e-07 Identities = 38/132 (28%), Positives = 64/132 (48%), Gaps = 5/132 (3%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDF-PVIAQF 81 V AP+ +S +R + + L F M+ + + R ++ + + P+ AQ Sbjct: 17 VYAPLAGFSDYPYRCMSALYQPGLMFCEMVKVEGILY-APERTSKLLDYNENMRPIGAQL 75 Query: 82 AANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140 +N + +A+K++ D +DLNCGCP KDG G LL PE+I I+ + N Sbjct: 76 CGSNPETSGEAAKILEGLGFDLIDLNCGCPTDKITKDGSGSGLLKTPELIGRILDKIINS 135 Query: 141 LPNKFSISVKIR 152 + ++VKIR Sbjct: 136 V--SIPVTVKIR 145 >UniRef50_Q5LRN6 Cluster: TRNA-dihydrouridine synthase, putative; n=10; Rhodobacterales|Rep: TRNA-dihydrouridine synthase, putative - Silicibacter pomeroyi Length = 327 Score = 56.0 bits (129), Expect = 7e-07 Identities = 46/193 (23%), Positives = 85/193 (44%), Gaps = 6/193 (3%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIA-QF 81 + APM + FR LV F A + + M+ + Q +K E + D A Q Sbjct: 15 ILAPMAGITDRPFRDLVMEFGAGMVVSEMVASQEMVQ-AKPGVRERAELSADVENTAVQL 73 Query: 82 AANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGY-GCSLLSKPEIIYDIVKGLRN 139 A + +A++ V +D+N GCP K + +GY G +LL P+ +++ + Sbjct: 74 AGRDTHWIAEAARQVADRGARVIDINMGCPAK-KVTNGYSGSALLKTPDHALRLIEAVVA 132 Query: 140 VLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM-EEHCTKSSGPVDINGLKEVR 198 + ++ ++ + + + ++ + GV +T C G D + VR Sbjct: 133 AVDVPVTLKTRLGWDDTLMNAPDVARRAAEAGVRMVTIHGRTRCQFYKGRADWAAIAAVR 192 Query: 199 EALSVPMVANGGV 211 EA+ VP++ANG + Sbjct: 193 EAVDVPLIANGDI 205 >UniRef50_Q4QEF9 Cluster: Putative uncharacterized protein; n=3; Leishmania|Rep: Putative uncharacterized protein - Leishmania major Length = 595 Score = 56.0 bits (129), Expect = 7e-07 Identities = 46/201 (22%), Positives = 87/201 (43%), Gaps = 10/201 (4%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 V AP+ + FR + ++F AD+ + M + + + K+ + ++ Q A Sbjct: 238 VLAPLTTVGNLPFRRICKSFGADVTLSEMAVVFNLNRLQKSEWSLLRRHESEDIFGIQLA 297 Query: 83 ANNRDD---FVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139 + + F A + D +D+NCGCP + +K G GC L + E + D+V+ L Sbjct: 298 VSRPQEAATFAQALEASGFSYDFLDINCGCPVEKIVKSGCGCGLWQRTERLRDVVESLAI 357 Query: 140 VLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT----SMEEHCTKSSGPVDINGLK 195 +I +I L DI + G +T S ++ TK + + + + Sbjct: 358 YQSRPVAIKCRIGLDEDIPTLHQQIHRYSAWGAAAVTVHGRSRKQRYTKFA---NWDYVD 414 Query: 196 EVREALSVPMVANGGVKHLND 216 + + S+P++ NG + L D Sbjct: 415 QCAQLTSLPVIGNGDIMSLED 435 >UniRef50_A4EC62 Cluster: Putative uncharacterized protein; n=1; Collinsella aerofaciens ATCC 25986|Rep: Putative uncharacterized protein - Collinsella aerofaciens ATCC 25986 Length = 347 Score = 55.6 bits (128), Expect = 9e-07 Identities = 42/224 (18%), Positives = 88/224 (39%), Gaps = 7/224 (3%) Query: 4 ICDIMEKFADAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKA 63 +C+ + A + +L APM + +R + R A+L ++ M+ S Sbjct: 3 LCEYSTRLLGAYAEQPFLM--APMAGVTDPAYRIMCRRRGANLAYSEMVSVAGLAYASNK 60 Query: 64 RANEFMTTTTDFPVIAQFAANNRDDFVDASKLVYPYVDG----VDLNCGCPQKWAMKDGY 119 + + + Q + + F A V V +D+N CP + + G Sbjct: 61 TWRLVLPADEEQQICVQLFGSKPEQFASAVAAVEERVGDRLSLIDINMACPARKVVTKGE 120 Query: 120 GCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSME 179 G +L+ P++ IV+ ++ ++ + + Q LE G + Sbjct: 121 GSALMRTPDLAEKIVEAAVGAAHVPVTVKIRKGFYAEDRNAATFAQMLEGAGAAAVAVHG 180 Query: 180 EHCTK-SSGPVDINGLKEVREALSVPMVANGGVKHLNDATTYMK 222 T+ +G D + + EV +A+ +P++ +G V DA +++ Sbjct: 181 RCATQLYTGQADWSVVDEVADAVEIPVIGSGDVFSAEDAAEHLQ 224 >UniRef50_Q251N6 Cluster: Putative uncharacterized protein; n=2; Desulfitobacterium hafniense|Rep: Putative uncharacterized protein - Desulfitobacterium hafniense (strain Y51) Length = 326 Score = 55.2 bits (127), Expect = 1e-06 Identities = 51/204 (25%), Positives = 98/204 (48%), Gaps = 10/204 (4%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDF-PVIAQFAA 83 APM + FR VR+ +T MI +D +R E + + + P I Q Sbjct: 20 APMAGVTDKAFRETVRSVGGLHVWTEMI-SDKALTYMNSRTLEMLDLSGEASPRIVQLFG 78 Query: 84 NNRDDFVDASKL-VYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 + + A+ L V + +D+N GCP +K+G G +LL + I + + + Sbjct: 79 SEPEVMAKAAALAVERDAEIIDINMGCPTPKIVKNGEGSALLQDLPLAQRIAEAVVKAV- 137 Query: 143 NKFSISVKIRLLNDIKKTVI--LCQQLEKCGVTFLTSMEEHCTKS--SGPVDINGLKEVR 198 + ++VK+RL ++ V L +++E GV + S+ + +G + +G+K+V+ Sbjct: 138 -EVPVTVKMRLGWTAERIVAPELAKRVEAVGVQ-MVSVHGRTREQFYAGTANRDGIKKVK 195 Query: 199 EALSVPMVANGGVKHLNDATTYMK 222 +S+P++ANG + +A T ++ Sbjct: 196 GGVSIPVIANGDIFSPQEAKTVLE 219 >UniRef50_Q55724 Cluster: Probable tRNA-dihydrouridine synthase 1; n=15; Cyanobacteria|Rep: Probable tRNA-dihydrouridine synthase 1 - Synechocystis sp. (strain PCC 6803) Length = 355 Score = 55.2 bits (127), Expect = 1e-06 Identities = 52/193 (26%), Positives = 88/193 (45%), Gaps = 10/193 (5%) Query: 25 APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83 +P+ + + FR LVR + + +T M+ A + + + P+ Q Sbjct: 47 SPLSGVTDLVFRRLVRRYAPQAMLYTEMVSATEI-HHLRTLPQVMEIDPRENPISIQLF- 104 Query: 84 NNRDDFVD--ASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141 + R DF+ A K V VD+N GCP K G G SLL +P + IVK + V Sbjct: 105 DCRPDFMAEAAQKAVAQGAQSVDINMGCPVNKITKKGGGSSLLRQPAVAEAIVKTV--VA 162 Query: 142 PNKFSISVKIRL-LNDIKKTVI-LCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVR 198 ++VK RL +D + ++ Q+L+ G LT +G + +V+ Sbjct: 163 AVDVPVTVKTRLGWDDGEINIVEFAQRLQDAGAQMLTLHGRTRAQGYNGRARWQWIAKVK 222 Query: 199 EALSVPMVANGGV 211 +AL++P++ANG + Sbjct: 223 QALTIPVIANGDI 235 >UniRef50_Q1VN28 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3; n=1; Psychroflexus torquis ATCC 700755|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 - Psychroflexus torquis ATCC 700755 Length = 338 Score = 54.8 bits (126), Expect = 2e-06 Identities = 44/190 (23%), Positives = 82/190 (43%), Gaps = 5/190 (2%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 APM + + +R L + AD T A + + + T + P I Q Sbjct: 17 APMAGVTDLAYRLLAKECGADFTVTEFTAASGLTRKNTNSWLKVETDPREKPFIPQIFGG 76 Query: 85 NRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNK 144 + + ++ D +D+N GCP ++ G +LL P+ + +V+ R + Sbjct: 77 DISEMAKTVGMLEDRSDVIDINFGCPAPKVCRNDAGAALLRDPDKVVSMVR--RCIESTN 134 Query: 145 FSISVKIRL-LNDIKKTVI-LCQQLEKCGVTFLTSMEEHC-TKSSGPVDINGLKEVREAL 201 I+VK+RL T + + ++L GV + + SG D + +KE+ ++ Sbjct: 135 VPITVKMRLGTGSGPNTALEISKRLADEGVMRICVHGRTLRQRYSGIADWDQIKEISNSV 194 Query: 202 SVPMVANGGV 211 +P++ANG V Sbjct: 195 DIPVIANGDV 204 >UniRef50_Q7R9R0 Cluster: Uncharacterized protein family UPF0034, putative; n=7; Plasmodium|Rep: Uncharacterized protein family UPF0034, putative - Plasmodium yoelii yoelii Length = 531 Score = 54.8 bits (126), Expect = 2e-06 Identities = 35/131 (26%), Positives = 65/131 (49%), Gaps = 5/131 (3%) Query: 25 APMVRYSKVHFRTLVRNFNADL-CFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83 APM+ + HFR LVR + + +T MI+ ++ N + P++ Q Sbjct: 157 APMINVTNRHFRALVRIISKKVQLWTEMIVDNTLLYNINNLEEHLGFNKNEHPIVCQLGG 216 Query: 84 NNRDDFVDASKLV-YPYVDGVDLNCGCPQ-KWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141 ++ +A+ LV D +++N GCP K A K +G L+ P+++ +IV ++ + Sbjct: 217 SDPTSLSEAAILVEQAGYDEININVGCPSTKVANKGAFGAYLMKNPQLVKNIVYEIKKKV 276 Query: 142 PNKFSISVKIR 152 + ++VKIR Sbjct: 277 --QIPVTVKIR 285 >UniRef50_Q7R684 Cluster: GLP_574_116690_118078; n=1; Giardia lamblia ATCC 50803|Rep: GLP_574_116690_118078 - Giardia lamblia ATCC 50803 Length = 462 Score = 54.4 bits (125), Expect = 2e-06 Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 4/101 (3%) Query: 76 PVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPE-IIYDIV 134 P++ Q N DD ++ P+ G+DLN GC ++A+ G G L+ K E +I + Sbjct: 97 PLVVQLTVNEYDDVDKICSILAPWCVGIDLNLGCGAQFAVSGGRGQRLVDKAENVIARFL 156 Query: 135 KGLRNVLPN---KFSISVKIRLLNDIKKTVILCQQLEKCGV 172 K L+ + + + S S+K RLL +++TV K GV Sbjct: 157 KALQQIEDSGGRRISFSIKQRLLGSVEETVNKMCAFYKLGV 197 >UniRef50_Q21L63 Cluster: Dihydrouridine synthase, DuS; n=1; Saccharophagus degradans 2-40|Rep: Dihydrouridine synthase, DuS - Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) Length = 318 Score = 54.0 bits (124), Expect = 3e-06 Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 4/117 (3%) Query: 103 VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVI 162 +DLN GCP K + G LL + + ++DIV +R P ++ KIR L + + Sbjct: 97 IDLNFGCPAKTVNRHKGGACLLDETDTVFDIVNAVRKATPASTPVTAKIR-LGYLNRDSY 155 Query: 163 L--CQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVREALSVPMVANGGVKHLND 216 L + +E G L T P + + ++R+ LS+P+VANG + L D Sbjct: 156 LRNAKAIEAAGANELCVHARSKTDGYQPPAYWHYIGDIRDNLSIPVVANGEIWSLED 212 >UniRef50_A7DPL5 Cluster: Putative TIM-barrel protein, nifR3 family; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Putative TIM-barrel protein, nifR3 family - Candidatus Nitrosopumilus maritimus SCM1 Length = 320 Score = 54.0 bits (124), Expect = 3e-06 Identities = 52/205 (25%), Positives = 86/205 (41%), Gaps = 15/205 (7%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDF--------P 76 APM S R + A L T S + + E M T +F P Sbjct: 12 APMAGVSDPALRLQCKKMGAGLVVTEFTSIHSIIAKEE-QLKENMKTIQEFIEFSEQERP 70 Query: 77 VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136 + Q ++ A+ +V PY D +D N GCP + G +LL + + I + Sbjct: 71 ISVQLFGSDLYALEKAATIVEPYFDIIDYNMGCPAPHITQQMAGGALLQEVNLTQQIFET 130 Query: 137 LRNVLPNKFSISVKIRL-LNDIKKTVI--LCQQLEKCGVTFLTSMEEHCTKS-SGPVDIN 192 L N + K +++KIR + D K + + + E G+ +T ++ SG D Sbjct: 131 LVNAV--KKPVTLKIRSGVTDASKFLFRDIAEIAEDQGIQMITFHPRTVSQGYSGSADWK 188 Query: 193 GLKEVREALSVPMVANGGVKHLNDA 217 +KE++E ++P+V NG + DA Sbjct: 189 LIKELKEISNIPVVGNGDITTPEDA 213 >UniRef50_UPI00015B6197 Cluster: PREDICTED: similar to CG10463-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to CG10463-PA - Nasonia vitripennis Length = 584 Score = 53.6 bits (123), Expect = 4e-06 Identities = 48/198 (24%), Positives = 79/198 (39%), Gaps = 8/198 (4%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 AP+ + FR + + F AD+ M LA + + ++ Q A N Sbjct: 295 APLTTVGNLPFRRICKEFGADITCGEMALAPRLLKGVREEWALVKRHESEDLFGVQIAGN 354 Query: 85 NRDDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 N +L+ VD VDLN GCP K G GC +L++ I+ +VK VL Sbjct: 355 NPGVLTRCCQLLNDETEVDFVDLNVGCPIDLVYKQGGGCGMLNRLNILESVVKSATEVLD 414 Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT----SMEEHCTKSSGPVDINGLKEVR 198 F++ + + D L + + G + + S E+ TK + I +V Sbjct: 415 IPFTVKTRTGVYADKPIAHKLMSKFKDWGASMINIHGRSREQRYTKLADWDYIEKCAQV- 473 Query: 199 EALSVPMVANGGVKHLND 216 A +P+ G + +D Sbjct: 474 -ASPIPVYGTGDILSWDD 490 >UniRef50_Q0VPD7 Cluster: TIM-barrel protein, yjbN family; n=4; Bacteria|Rep: TIM-barrel protein, yjbN family - Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) Length = 348 Score = 53.6 bits (123), Expect = 4e-06 Identities = 49/213 (23%), Positives = 97/213 (45%), Gaps = 20/213 (9%) Query: 25 APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83 APM+ ++ +R L R L +T M++A + + R +F + PV Q Sbjct: 37 APMMDWTTRDYRFLARLITRHTLLYTEMVVAQAILHGDRDRFLDF--NDEEHPVALQLGG 94 Query: 84 NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 ++ A+++ Y D ++LN GCP + G L+++PE++ V+ ++ + Sbjct: 95 SDPQQLAQATRIAGDYGYDEINLNVGCPSDRVQQGKIGAILMAEPELVARCVEAMQAEV- 153 Query: 143 NKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS--SG----------PV 189 ++VK R+ ++D L + +++ + TS+ H K+ SG P+ Sbjct: 154 -TVPVTVKTRIGIDDQDDYDFLYRFVDRMEASGCTSLTIHARKAILSGLSPKENRDIPPL 212 Query: 190 DINGLKEVREAL-SVPMVANGGVKHLNDATTYM 221 ++ A + ++ NGGVK LN+ +M Sbjct: 213 IYQRAYAIKHAFPHIEIILNGGVKTLNEVHEHM 245 >UniRef50_Q91XI1 Cluster: tRNA-dihydrouridine synthase 3-like; n=7; Euteleostomi|Rep: tRNA-dihydrouridine synthase 3-like - Mus musculus (Mouse) Length = 637 Score = 53.6 bits (123), Expect = 4e-06 Identities = 47/204 (23%), Positives = 82/204 (40%), Gaps = 8/204 (3%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 AP+ + FR + + F AD+ M + + Q + + Q Sbjct: 297 APLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALLKRHPCEDIFGVQLEGA 356 Query: 85 NRDDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 D ++L+ VD VD+N GCP K G GC+L+++ IV+G+ VL Sbjct: 357 FPDTMTKCAELLNRTIDVDFVDINVGCPIDLVYKKGGGCALMNRSAKFQQIVRGVNGVLD 416 Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT----SMEEHCTKSSGPVDINGLKEVR 198 ++ ++ + + L +L GV +T S E+ T+ + I +V Sbjct: 417 VPLTVKMRTGVQERVSLAHRLLPELRDWGVALVTLHGRSREQRYTRLADWPYIEQCAKV- 475 Query: 199 EALSVPMVANGGVKHLNDATTYMK 222 A +P+ NG + DA M+ Sbjct: 476 -ASPMPLFGNGDILSFEDANCAMQ 498 >UniRef50_A4RQU5 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 608 Score = 53.2 bits (122), Expect = 5e-06 Identities = 49/211 (23%), Positives = 84/211 (39%), Gaps = 9/211 (4%) Query: 17 NKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP 76 +K YL AP+ + FR + + AD+ M L S Q + ++ Sbjct: 247 DKLYL---APLTTVGNLPFRRVCKTLGADITCGEMALCTSLLQGLPSEWALLRRHKSEDI 303 Query: 77 VIAQFAANNRDDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134 Q D +L+ VD +D+N GCP + GYG +L KP+ + ++ Sbjct: 304 FGVQICGGYPDSVTRCCQLLEDTIDVDFIDINMGCPIDSVCQKGYGSMMLEKPKKMETVI 363 Query: 135 KGLRNVLPNKFSISVKIRLLNDIKKTV--ILCQQLEKCGVTFLT-SMEEHCTKSSGPVDI 191 + L K S++ K R+ K V ++ + G +T + D Sbjct: 364 RAASAAL-GKCSLTFKTRMAYTDKSRVAHTFAPKVAEWGAAAMTLHGRTRAQRYRSVADW 422 Query: 192 NGLKEVREALSVPMVANGGVKHLNDATTYMK 222 K +E+ SVP++ NG V D T+++ Sbjct: 423 EYTKLTKESSSVPLIGNGDVYMQKDYYTHLE 453 >UniRef50_Q8YMN5 Cluster: Transcriptional regulator; n=5; Bacteria|Rep: Transcriptional regulator - Anabaena sp. (strain PCC 7120) Length = 349 Score = 52.8 bits (121), Expect = 6e-06 Identities = 50/206 (24%), Positives = 88/206 (42%), Gaps = 8/206 (3%) Query: 21 LKVCAPMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQNSKARANEFMTTTTDFPVIA 79 L APM + + F ++ ++ + D FT + + ++ + T PV A Sbjct: 26 LTALAPMQDVTNLWFMKVIAHYGSPDYFFTEYFRVNDTSRLNRGILSAITENDTGRPVFA 85 Query: 80 QFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLR 138 Q + D V +K + Y + GVDLN GCP + G LL P + I++ LR Sbjct: 86 QMIGESIPDLVRTAKELCGYNIAGVDLNMGCPAPRIYRKNVGGGLLLSPAKVEQILEELR 145 Query: 139 NVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS--SGPVDINGLKE 196 + N ++VK+R+ + T + L S+ K G V + + E Sbjct: 146 QAV-NDRPLTVKMRVGFENTDTFYEILDIVNRHNIDLLSLHGRTVKDMYHGAVKYDLIAE 204 Query: 197 VREALSVPMVANGGVKHLNDATTYMK 222 + P++ANG +++ ATT ++ Sbjct: 205 AVRRVDCPVLANG---NIHSATTALE 227 >UniRef50_Q6MAU6 Cluster: Putative uncharacterized protein yohI; n=1; Candidatus Protochlamydia amoebophila UWE25|Rep: Putative uncharacterized protein yohI - Protochlamydia amoebophila (strain UWE25) Length = 326 Score = 52.8 bits (121), Expect = 6e-06 Identities = 39/164 (23%), Positives = 70/164 (42%), Gaps = 10/164 (6%) Query: 65 ANEFMTTTT-DFPVIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCS 122 AN + T P AQ ++ + + ++ V +DLNCGCP G G S Sbjct: 57 ANRYEANETFPIPQAAQLMGSDPELMAEMARAVERRGAQRIDLNCGCPSNTVTGRGAGSS 116 Query: 123 LLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQL---EKCGVTFLTSME 179 LL +P+ +Y + K + + ++ V +L + T + L + G+ +LT Sbjct: 117 LLKEPDHLYKVAKSMVEAV----NVPVTAKLRSGFTDTSLFHDNLLAAQASGIKYLTLHP 172 Query: 180 EHCTKSSG-PVDINGLKEVREALSVPMVANGGVKHLNDATTYMK 222 G P + + ++ L +P+V NG + + DA +K Sbjct: 173 RTKVDGYGPPAKWELIAQAKQLLKIPVVGNGDILTVQDALNMLK 216 >UniRef50_Q4FLD8 Cluster: Putative uncharacterized protein; n=2; Candidatus Pelagibacter ubique|Rep: Putative uncharacterized protein - Pelagibacter ubique Length = 330 Score = 52.8 bits (121), Expect = 6e-06 Identities = 31/131 (23%), Positives = 69/131 (52%), Gaps = 6/131 (4%) Query: 25 APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83 APM+ + H R +R + + L ++ M+++++ + K + EF + P+ Q Sbjct: 8 APMMDCTDRHERFFLRLISKNTLLYSEMVVSEAIHRGDKKKLLEF--NINEKPIALQIGG 65 Query: 84 NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 ++ +A+K+ + D ++LN GCP K K+ +G L+ +P ++ D + +++V Sbjct: 66 SSPTLLAEATKVGEDFGYDEINLNLGCPSKKVEKNKFGACLMKEPNLVADCLSKMQSV-- 123 Query: 143 NKFSISVKIRL 153 K +++K R+ Sbjct: 124 TKLPVTIKTRI 134 >UniRef50_Q30WR3 Cluster: Dihydrouridine synthase family protein; n=3; Desulfovibrio|Rep: Dihydrouridine synthase family protein - Desulfovibrio desulfuricans (strain G20) Length = 376 Score = 52.8 bits (121), Expect = 6e-06 Identities = 47/203 (23%), Positives = 85/203 (41%), Gaps = 6/203 (2%) Query: 25 APMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQNSKARANEFMTTTTDFPVIA--QF 81 APM + +R ++ +F L FT M A + + AR+ F + P + F Sbjct: 62 APMAGLGHIAYRQVLESFGGCGLVFTGMCSARAVPTENPARSPVFSWRPEELPALVCQLF 121 Query: 82 AANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141 A+ +D A ++ GVD+N GC +K G G LL PE +V +R + Sbjct: 122 GADPQDMAAAARRVESEGFFGVDINMGCSVAPIVKKGCGADLLRDPERAVRMVDAVRRAV 181 Query: 142 PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHC--TKSSGPVDINGLKEVRE 199 + ++ D + V L ++L+ G L ++ P + + V++ Sbjct: 182 SVPVFVKMRTGWSPDPEPAVNLARRLQDAGADALVFHPRVAPDRRTHRPRTAH-IGLVKD 240 Query: 200 ALSVPMVANGGVKHLNDATTYMK 222 A+ +P++ NG V D ++ Sbjct: 241 AVDIPVIGNGDVFDAADCAAMLE 263 >UniRef50_A6NW05 Cluster: Putative uncharacterized protein; n=1; Bacteroides capillosus ATCC 29799|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 307 Score = 52.8 bits (121), Expect = 6e-06 Identities = 44/190 (23%), Positives = 81/190 (42%), Gaps = 6/190 (3%) Query: 27 MVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAANNR 86 M + + FRT+ R A T M+ A + C K + P AQ ++ Sbjct: 1 MAGVTDMAFRTICRELGAGYTITEMVSAKALCYQDKKSIPLLKLGEGEHPCAAQIFGSDE 60 Query: 87 DDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNK 144 +A+ + D +D+N GCP G G L+ + + + + + Sbjct: 61 KCMEEAAAIAGEVSGADIIDINMGCPVPKVANSGDGSGLMRDVDKAVRVAEAVVRGAGER 120 Query: 145 FSISVKIRLLNDIKKT--VILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVREAL 201 ++VK RL D V + +E GV+ + T+ +G + + ++EV++A+ Sbjct: 121 -PVTVKFRLGWDKGSINCVEFAKAMEAAGVSAVAVHGRTRTQMYAGTANWDYIREVKQAV 179 Query: 202 SVPMVANGGV 211 S+P++ANG V Sbjct: 180 SIPVIANGDV 189 >UniRef50_A6GHV6 Cluster: Dihydrouridine synthase family protein; n=1; Plesiocystis pacifica SIR-1|Rep: Dihydrouridine synthase family protein - Plesiocystis pacifica SIR-1 Length = 321 Score = 52.8 bits (121), Expect = 6e-06 Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 2/110 (1%) Query: 102 GVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRL-LNDIKKT 160 G+DLN GCP K G +LL P + + + +R +P + ++VKIR+ D Sbjct: 88 GIDLNFGCPAKTVNSSDGGATLLKDPCRVEAVTRAVRAAVPAELPVTVKIRVGWEDPSPV 147 Query: 161 VILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREALSVPMVANG 209 V + + E G ++LT PVD + + A+S+ +VANG Sbjct: 148 VEIARAAEAGGASWLTIHGRTRRQLYKPPVDYEAIGRAQAAVSMAVVANG 197 >UniRef50_Q5CRK5 Cluster: Ylr401cp-like protein with 2 CCCH domains plus Dus1p tRNA dihydrouridine synthase Tim barrel; n=2; Cryptosporidium|Rep: Ylr401cp-like protein with 2 CCCH domains plus Dus1p tRNA dihydrouridine synthase Tim barrel - Cryptosporidium parvum Iowa II Length = 707 Score = 52.8 bits (121), Expect = 6e-06 Identities = 31/133 (23%), Positives = 58/133 (43%), Gaps = 3/133 (2%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 + AP+ + FR L F AD+ + M+L + + + + Q A Sbjct: 319 ILAPLTTVGNLPFRRLCLKFGADVTVSEMVLCNEILSGKASELALLKKSPEEKYFGIQLA 378 Query: 83 ANNRDDFVDASKLVYPYV--DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140 N+ + + + + D +D+N CP K G G L+ + + +VKGL+ V Sbjct: 379 GGNKSTIIKTGEFINEHCEFDFIDINAACPLKSLHDKGAGSILVDRVSELETMVKGLKKV 438 Query: 141 LPNKFSISVKIRL 153 + K ++VK+R+ Sbjct: 439 MDGKL-VTVKVRM 450 >UniRef50_A7S213 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 570 Score = 52.8 bits (121), Expect = 6e-06 Identities = 54/217 (24%), Positives = 96/217 (44%), Gaps = 19/217 (8%) Query: 17 NKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP 76 +K YL AP+ + FR + + + AD+ M + + Q ++ +++ Sbjct: 218 DKLYL---APLTTIGNLPFRRICKQYGADITCGEMAMCTNLLQGQQSEWALVKRHSSEDI 274 Query: 77 VIAQFAANNRDDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134 Q D ++L+ VD +D+N GCP G G +L+ + + IV Sbjct: 275 FGVQLCGAFPDTMTKCAELLQKETDVDFIDINTGCPIDLVFNKGAGSALMERKGKLQQIV 334 Query: 135 KGLRNVLPNKFSISVKIRL-LNDIKKT---VILCQQLEKCGVTFLT----SMEEHCTKSS 186 +G+++V+ ++VKIR ++D K T L L G +T S E+ TKS+ Sbjct: 335 QGMKSVI--DIPLTVKIRAGIHDKKYTWNAHKLVGNLRDWGTDMVTIHGRSREQRYTKSA 392 Query: 187 GPVDINGLKEVREALS-VPMVANGGVKHLNDATTYMK 222 D + + EV + S +P+ NG + DA + K Sbjct: 393 ---DWDYISEVAKLASPMPVFGNGDILSFEDAMQHRK 426 >UniRef50_O83945 Cluster: Probable tRNA-dihydrouridine synthase; n=2; Treponema|Rep: Probable tRNA-dihydrouridine synthase - Treponema pallidum Length = 340 Score = 52.8 bits (121), Expect = 6e-06 Identities = 31/133 (23%), Positives = 61/133 (45%), Gaps = 5/133 (3%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 AP+ YS FR++ + A +T M+ +++ ++S + + Q + Sbjct: 24 APVAGYSDSAFRSIAIEWEASFTYTEMVSSEAMVRDSLNTKRLIRRASNETHYAIQIFGS 83 Query: 85 NRDDFVDASKLVYPYVDG--VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL- 141 N + +KL+ +D+N GCP K G G +L +P +Y++VK + + + Sbjct: 84 NPAVMAETAKLIVDSAQPSCIDINAGCPMPKITKTGAGAALTREPTRLYEVVKAVADAVY 143 Query: 142 --PNKFSISVKIR 152 + ++VKIR Sbjct: 144 AQDARIPVTVKIR 156 >UniRef50_Q6MRF1 Cluster: Transcription regulator homolog yacF; n=1; Bdellovibrio bacteriovorus|Rep: Transcription regulator homolog yacF - Bdellovibrio bacteriovorus Length = 337 Score = 52.4 bits (120), Expect = 9e-06 Identities = 45/198 (22%), Positives = 84/198 (42%), Gaps = 6/198 (3%) Query: 18 KTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPV 77 KT V APM + FRT ++ +A + T ++ A S + P+ Sbjct: 8 KTNPFVLAPMAGITDHAFRTFIKKLDASVVVTELVSASGIEYKSDRTLKLMSFDESQRPI 67 Query: 78 IAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136 Q + A+++ D VDLN GCP +K G G ++L P + +V Sbjct: 68 GIQLFGEEPEIVARAAQVAEADGCDFVDLNFGCPVPKVVKKGAGSAILKDPAAVQKMVST 127 Query: 137 LRNVLPNKFSISVKIRLLNDI--KKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDING 193 ++ + K +++KIR D + +C GV+++ +S +G D + Sbjct: 128 VKAAI--KIPLTIKIRTGWDANSRNATEICNIAYNEGVSWVAIHGRTRAQSYTGLADWDF 185 Query: 194 LKEVREALSVPMVANGGV 211 + +V+ +P++ NG + Sbjct: 186 IADVKANTKIPILGNGDI 203 >UniRef50_Q3E0H8 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3; n=5; Chloroflexi (class)|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 - Chloroflexus aurantiacus J-10-fl Length = 407 Score = 52.4 bits (120), Expect = 9e-06 Identities = 47/220 (21%), Positives = 93/220 (42%), Gaps = 3/220 (1%) Query: 1 MKEICDIMEKFADAKINKTYLKVCAPMVRYSKVHFRTLV-RNFNADLCFTPMILADSFCQ 59 ++EI + + A I + APM + FR ++ R L T M A S Sbjct: 64 LEEIARLPTSYQVAHIRIEPNIILAPMAGVTDSIFRRMILRLGGCGLVSTEMTNAASVSP 123 Query: 60 NSKARANEFMTTTTDFPVIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDG 118 + R + P+ Q + N+ D +A+++V D +D+NCGCP G Sbjct: 124 KALRRHRLLDYLPEERPLTMQISGNDPDLVANAARVVEQLGADIIDINCGCPSPKVTGGG 183 Query: 119 YGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM 178 +G +LL + +++ +R + ++ + + ++ E GV+ L Sbjct: 184 HGSALLRDLPKMERLLRAVREAVQIPVTLKFRAGWDEQSLNFIEAGKRAEAAGVSALALH 243 Query: 179 EEHCTKS-SGPVDINGLKEVREALSVPMVANGGVKHLNDA 217 + G D + + +++A+S+P++ +G V +DA Sbjct: 244 PRTREQGYKGQADWSRVAALKQAVSIPVIGSGDVTSAHDA 283 >UniRef50_Q884C6 Cluster: tRNA-dihydrouridine synthase C; n=8; Proteobacteria|Rep: tRNA-dihydrouridine synthase C - Pseudomonas syringae pv. tomato Length = 317 Score = 52.4 bits (120), Expect = 9e-06 Identities = 33/117 (28%), Positives = 55/117 (47%), Gaps = 4/117 (3%) Query: 103 VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVI 162 +DLN GCP K + G LL +PE+++ IV +R +P ++ K+RL + + Sbjct: 92 LDLNFGCPAKTVNRSRGGAILLKEPELLHTIVSQVRRAVPKDIPVTAKMRLGYENTDGAL 151 Query: 163 LCQQLEKCGVTFLTSMEEHCTKSSG---PVDINGLKEVREALSVPMVANGGVKHLND 216 C + G + TK G P + ++E + VP+VANG + + D Sbjct: 152 DCARALADGGAAQIVVHAR-TKVDGYKPPAHWEWIARIQEVVKVPVVANGEIWTVED 207 >UniRef50_Q489F6 Cluster: NifR3/Smm1 family protein; n=2; Proteobacteria|Rep: NifR3/Smm1 family protein - Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibriopsychroerythus) Length = 338 Score = 52.0 bits (119), Expect = 1e-05 Identities = 42/189 (22%), Positives = 80/189 (42%), Gaps = 2/189 (1%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 APM + FR L A L + M+ ++ N++ + Q A + Sbjct: 15 APMAGITDQPFRQLCCQLGAGLAVSEMLSSNPKVWNTEKSKLRMLHGDAAGIRSVQIAGS 74 Query: 85 NRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143 D+ A+K+ +D+N GCP K K G +LL +P + IV+ + N + Sbjct: 75 CPDELAFAAKVNADNGAQIIDINMGCPAKKVNKKLAGSALLREPAQVERIVQSVVNAVDI 134 Query: 144 KFSISVKIRLLNDIKKTVILCQQLEKCGVTFL-TSMEEHCTKSSGPVDINGLKEVREALS 202 ++ ++ D + + + + E G+ L G + + +K ++ A+S Sbjct: 135 PVTLKIRTGWCEDTRNGIEIAKIAENSGIASLAVHGRTRNDFYKGNAEYDTIKAIKLAIS 194 Query: 203 VPMVANGGV 211 +P+VANG + Sbjct: 195 IPVVANGDI 203 >UniRef50_Q1N033 Cluster: Putative uncharacterized protein; n=1; Oceanobacter sp. RED65|Rep: Putative uncharacterized protein - Oceanobacter sp. RED65 Length = 321 Score = 52.0 bits (119), Expect = 1e-05 Identities = 51/204 (25%), Positives = 86/204 (42%), Gaps = 14/204 (6%) Query: 25 APMVRYSKVHFRTLV-RNFNADLCFTPMI------LADSFCQNSKARANEFMTTTTDFPV 77 APM VH RTL+ R D C T + L + + ++ T PV Sbjct: 6 APMEGLVDVHMRTLLTRGGYFDYCVTEFLRVTTQLLPERSFRRICPESDHQWKTPAGTPV 65 Query: 78 IAQFAANNRDDFVD-ASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136 Q ++ + A + V++N GCP ++ G LL P+ I+ I++ Sbjct: 66 HLQLLGSDPVAMAENACRAAELGAPVVNINFGCPSRFVNGRCGGAYLLQFPDQIHTILES 125 Query: 137 LRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSG---PVDIN 192 +R LP ++ K+RL D + Q +E GV + TK G P + Sbjct: 126 VRKALPEHVPLTAKMRLGFKDDALALANAQAMESAGVRDICIHAR--TKVQGYRPPAHWH 183 Query: 193 GLKEVREALSVPMVANGGVKHLND 216 +K +++ + VP++ANG + + D Sbjct: 184 QIKNIKQQVKVPIIANGEIWNRRD 207 >UniRef50_Q056Y8 Cluster: TRNA-dihydrouridine synthase A; n=1; Buchnera aphidicola str. Cc (Cinara cedri)|Rep: TRNA-dihydrouridine synthase A - Buchnera aphidicola subsp. Cinara cedri Length = 348 Score = 51.6 bits (118), Expect = 1e-05 Identities = 40/148 (27%), Positives = 64/148 (43%), Gaps = 8/148 (5%) Query: 10 KFADAKINKTYLKV--CAPMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARAN 66 K + K+ K Y APM +Y+ H R +T MI + K Sbjct: 17 KINNIKMKKKYSNKFSVAPMFKYTDQHCLYFYRQLTKKTFLYTEMITIQKMLFSKKLFKK 76 Query: 67 EFMTTTTDFPVIAQFAANNRDDF-VDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLS 125 + + P+ Q A NN + A K + ++LN GCP K A +G L++ Sbjct: 77 KQIKKNN--PIAIQLAGNNPLFLSLCAKKAYFLGFKEINLNIGCPSKKAKSGNFGIYLMN 134 Query: 126 KPEIIYDIVKGLRNVLPNKFSISVKIRL 153 P ++Y+++K + +P IS+KIRL Sbjct: 135 NPILVYNLIKAIYLTVP--IQISIKIRL 160 >UniRef50_A1RNI1 Cluster: TIM-barrel protein, yjbN family; n=30; Bacteria|Rep: TIM-barrel protein, yjbN family - Shewanella sp. (strain W3-18-1) Length = 343 Score = 51.6 bits (118), Expect = 1e-05 Identities = 31/129 (24%), Positives = 58/129 (44%), Gaps = 5/129 (3%) Query: 25 APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83 APM+ ++ H+R R +A L +T M+ + R + + P+ Q Sbjct: 28 APMLDWTDRHYRYFARLMSAKALLYTEMVTTGAILHG---RGDYLAYNQEEHPLALQLGG 84 Query: 84 NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 +N D +KL D V+LN GCP +G L+++PE++ + V ++ V+ Sbjct: 85 SNPQDLARCAKLAAERGYDEVNLNVGCPSDRVQNGRFGACLMAEPELVAECVDAMKQVVD 144 Query: 143 NKFSISVKI 151 ++ +I Sbjct: 145 IPVTVKTRI 153 >UniRef50_A3LUK5 Cluster: Dihydrouridine synthase of tRNA; n=6; Saccharomycetales|Rep: Dihydrouridine synthase of tRNA - Pichia stipitis (Yeast) Length = 613 Score = 51.6 bits (118), Expect = 1e-05 Identities = 37/152 (24%), Positives = 70/152 (46%), Gaps = 6/152 (3%) Query: 6 DIMEKFADAK-INKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKAR 64 D K A+ K ++ K+ +P+ + +R L++ AD+ ++ M L+ Q + A Sbjct: 229 DAPYKIAEKKRLDFRNAKIVSPLTTVGNLPYRRLMKKLGADITYSEMALSVPLLQATNAE 288 Query: 65 ANEFMTTTTDFPVIA-QFAANNRDDFVDASKLVY---PYVDGVDLNCGCPQKWAMKDGYG 120 T++P Q A + ++++ +V ++LNCGCP + G G Sbjct: 289 WALPKAHRTEYPGYGVQIATSKHWAAAKVAEIISRETEHVSELNLNCGCPIDLLYRQGQG 348 Query: 121 CSLLSKPEIIYDIVKGLRNVLPNKFSISVKIR 152 +LL +P + I+K + N ++VKIR Sbjct: 349 SALLEQPARLVRILKAM-NASSGDIPVTVKIR 379 >UniRef50_UPI0000499494 Cluster: conserved hypothetical protein; n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved hypothetical protein - Entamoeba histolytica HM-1:IMSS Length = 515 Score = 51.2 bits (117), Expect = 2e-05 Identities = 41/191 (21%), Positives = 82/191 (42%), Gaps = 7/191 (3%) Query: 30 YSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAANNRDDF 89 + + FR +V+ F D+ T MI+A+S + + +++ Q N Sbjct: 180 FGNLPFRKVVKRFGCDVTMTEMIMAESLVEGKTSEWALVKRDSSEDIFGIQLCVGNSMLA 239 Query: 90 VDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSIS 148 A +++ D +LNC CP + K G G L+ +P+ I ++ +R+V +I Sbjct: 240 AKACQVLNSVDCDFYELNCACPIDYVYKKGMGAQLIERPKRIESLLHAMRSVTERPVAIK 299 Query: 149 VKIRLLNDIKKTVIL--CQQLEKCGVTFL-TSMEEHCTKSSGPVDINGLKEVREALSVPM 205 V+ ++ + V+L C V+ + ++ TKS+ D + +K+ P+ Sbjct: 300 VRTGKSSNTIQDVLLPNCADYGAAMVSIHGRTRDQRYTKSA---DWDFIKQATTITQCPV 356 Query: 206 VANGGVKHLND 216 + G + D Sbjct: 357 IGVGDIYGYKD 367 >UniRef50_Q012U0 Cluster: Nitrogen regulation family protein; n=2; Ostreococcus|Rep: Nitrogen regulation family protein - Ostreococcus tauri Length = 490 Score = 51.2 bits (117), Expect = 2e-05 Identities = 34/152 (22%), Positives = 73/152 (48%), Gaps = 9/152 (5%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPV-----IA 79 APM+ Y+ HFR + R +A + D ++ + D+PV + Sbjct: 105 APMMEYTTAHFRVMCRLMSAKTWLWTEMEVDQTLTHAVLEGTR-VDRFLDYPVETAATVL 163 Query: 80 QFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQ-KWAMKDGYGCSLLSKPEIIYDIVKGL 137 Q ++ + A+ + PY + ++LN GCP K A K +G +L+++P ++ + ++ + Sbjct: 164 QLGGSDPEILGRATAIAAPYGYEEINLNSGCPSPKVAGKGCFGAALMTEPRLVAECLQAM 223 Query: 138 RNVLPNKFSISVKIRL-LNDIKKTVILCQQLE 168 P+ +S+K R+ +++ LC+ ++ Sbjct: 224 NENAPSGTPVSIKCRIGVDECDSYDALCEYVD 255 >UniRef50_A7HK00 Cluster: Dihydrouridine synthase DuS; n=4; Thermotogaceae|Rep: Dihydrouridine synthase DuS - Fervidobacterium nodosum Rt17-B1 Length = 322 Score = 50.8 bits (116), Expect = 3e-05 Identities = 38/127 (29%), Positives = 55/127 (43%), Gaps = 1/127 (0%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 APM + FR L A FT MI A S N K F V Q + Sbjct: 14 APMAGVTDYPFRKLCLQHGAYFAFTEMISAKSVIINVKINEIYFPRQDEKDRVGVQLFGS 73 Query: 85 NRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNK 144 + + +A+ +V VDLN GCP +K G G +LL +V+ +R+VL + Sbjct: 74 DYAELSEAAAIVQEKGLWVDLNAGCPVSKVIKKGAGSALLKDLGEFRKVVRAMRSVL-KR 132 Query: 145 FSISVKI 151 F++ +I Sbjct: 133 FTVKTRI 139 >UniRef50_A4BCJ5 Cluster: NifR3/Smm1 family protein; n=2; Gammaproteobacteria|Rep: NifR3/Smm1 family protein - Reinekea sp. MED297 Length = 314 Score = 50.8 bits (116), Expect = 3e-05 Identities = 23/52 (44%), Positives = 33/52 (63%) Query: 102 GVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRL 153 G+DLN GCP K G LL++PE IY +V+ +R+ LP ++S K+RL Sbjct: 91 GLDLNFGCPSKTVNASKGGAVLLTEPESIYAVVRSVRDALPGDQTLSAKMRL 142 >UniRef50_A4AAB0 Cluster: TRNA-dihydrouridine synthase C; n=2; unclassified Gammaproteobacteria|Rep: TRNA-dihydrouridine synthase C - Congregibacter litoralis KT71 Length = 328 Score = 50.8 bits (116), Expect = 3e-05 Identities = 41/152 (26%), Positives = 67/152 (44%), Gaps = 7/152 (4%) Query: 71 TTTDFPVIAQFAANNRDDFVD-ASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129 T++ PV Q + + AS+ GVDLN GCP K + G +L +PE Sbjct: 65 TSSGVPVYLQILGGDPSVVAENASRAAELGAPGVDLNFGCPAKTVNRSDGGSIILREPER 124 Query: 130 IYDIVKGLRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSG- 187 ++ IV R LP +SVKIRL + + + + ++ + L T++ G Sbjct: 125 VHRIVAATRQALPPSVPLSVKIRLGFDSSDRFLDIVSGIDAARPSELVIHAR--TRADGY 182 Query: 188 --PVDINGLKEVREALSVPMVANGGVKHLNDA 217 P + R +P++ANG + + DA Sbjct: 183 RPPAYWEHIALARSKTRLPLIANGEIWGVGDA 214 >UniRef50_UPI0000E472BC Cluster: PREDICTED: similar to tRNA-dihydrouridine synthase; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to tRNA-dihydrouridine synthase - Strongylocentrotus purpuratus Length = 499 Score = 50.4 bits (115), Expect = 3e-05 Identities = 39/146 (26%), Positives = 68/146 (46%), Gaps = 17/146 (11%) Query: 7 IMEKFADAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARAN 66 + E + ++++ + APMVR + R L + AD+ + ++ D + N Sbjct: 27 VPEIWMSSRLSYANKVILAPMVRIGTLPTRLLALEYGADIVYCQELI-DFKMLTCRRHVN 85 Query: 67 EFMTT----TTDFPVIAQFAANNRDDFV------DA------SKLVYPYVDGVDLNCGCP 110 + T + D VI + + D V DA +K+V V G+D+N GCP Sbjct: 86 RVLGTVDYISKDDVVIFRTCSKETDRLVFQMGTADAQRALRVAKMVEKDVSGIDINMGCP 145 Query: 111 QKWAMKDGYGCSLLSKPEIIYDIVKG 136 + +++K G G +LL KP+ I +I G Sbjct: 146 KDFSLKGGMGAALLQKPDTIKEIPSG 171 >UniRef50_Q2UL89 Cluster: Uncharacterized conserved protein; n=15; Pezizomycotina|Rep: Uncharacterized conserved protein - Aspergillus oryzae Length = 730 Score = 50.4 bits (115), Expect = 3e-05 Identities = 28/83 (33%), Positives = 45/83 (54%), Gaps = 4/83 (4%) Query: 74 DFPVIAQFAANNRDDFVDASKLVYPYVDG---VDLNCGCPQKWAMKDGYGCSLLSKPEII 130 DF AQ AAN + A++++ Y +DLNCGCP ++G G +LL P + Sbjct: 394 DFRFGAQIAANKHWQALKATEVLSAYTPNLRVIDLNCGCPIDLLFREGAGSALLEHPSKL 453 Query: 131 YDIVKGLRNVLPNKFSISVKIRL 153 I++G+ N + + I+ KIR+ Sbjct: 454 ERILRGM-NAVSQEIPITAKIRM 475 >UniRef50_A6DU09 Cluster: Dihydrouridine synthase family protein; n=1; Lentisphaera araneosa HTCC2155|Rep: Dihydrouridine synthase family protein - Lentisphaera araneosa HTCC2155 Length = 334 Score = 50.0 bits (114), Expect = 5e-05 Identities = 35/79 (44%), Positives = 45/79 (56%), Gaps = 6/79 (7%) Query: 77 VIAQFAANNRDDFVDA-SKLVYPYV-DGVDLNCGCPQKWAMKDGYGCS-LLSKPEIIYDI 133 ++AQ N D F +A SK V P V DGVD+N GCP +K G GCS L++ PEI ++ Sbjct: 82 IVAQVWGKNPDKFSEAISKYVDPEVFDGVDINMGCPVAKIVKQG-GCSALINTPEIAKEL 140 Query: 134 VKGLRNVLPNKFSISVKIR 152 V L K +SVK R Sbjct: 141 V--LAAKAATKLPVSVKTR 157 >UniRef50_Q89LQ7 Cluster: Nitrogen regulation protein; n=22; Alphaproteobacteria|Rep: Nitrogen regulation protein - Bradyrhizobium japonicum Length = 371 Score = 49.6 bits (113), Expect = 6e-05 Identities = 43/191 (22%), Positives = 78/191 (40%), Gaps = 7/191 (3%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 APM + R LV A L + M +D N + T P + Q A Sbjct: 53 APMSGVTDSPVRRLVAELGAGLVVSEMTASDELA-NGHRMSRLRCEATGIGPHVVQLAGC 111 Query: 85 NRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143 + +++ D +D+N GCP + G +L+ + ++ + Sbjct: 112 EAHWMAEGARIAEAEGADIIDINMGCPARHVTGGQSGSALMRDLDHAVGLIDA--TIAAV 169 Query: 144 KFSISVKIRLLND--IKKTVILCQQLEKCGVTFLTSM-EEHCTKSSGPVDINGLKEVREA 200 K +++K+RL D + L ++ E G+ +T C G D + ++ VREA Sbjct: 170 KVPVTLKMRLGWDDRSRNAPELARRAEAAGIKLVTVHGRTRCQFYKGEADWDAIRTVREA 229 Query: 201 LSVPMVANGGV 211 +S+P++ NG + Sbjct: 230 ISIPLIVNGDI 240 >UniRef50_O51243 Cluster: Putative uncharacterized protein BB0225; n=3; Borrelia burgdorferi group|Rep: Putative uncharacterized protein BB0225 - Borrelia burgdorferi (Lyme disease spirochete) Length = 335 Score = 49.6 bits (113), Expect = 6e-05 Identities = 38/132 (28%), Positives = 63/132 (47%), Gaps = 7/132 (5%) Query: 25 APMVRYSKVHFRTLVRNFNADLC-FTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83 APMV + HFR L+R + + +TPMI A S + + + P+ Q A Sbjct: 10 APMVNITDEHFRYLIRLLSKKVTLYTPMISAKSIIMGDVKKIVK--QNPLESPIAIQIAT 67 Query: 84 NNRDDFVDASKLVYPYV--DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141 N+++D + A +++ + D +LN GCP G L+ + +I+K ++ Sbjct: 68 NSKNDALKAIQILEKHFNFDEYNLNVGCPSLKIQNANCGACLMGNANQVGEILKTMKE-N 126 Query: 142 PNKFSISVKIRL 153 NK IS+K RL Sbjct: 127 TNK-PISIKHRL 137 >UniRef50_Q1JWD3 Cluster: Dihydrouridine synthase, DuS; n=1; Desulfuromonas acetoxidans DSM 684|Rep: Dihydrouridine synthase, DuS - Desulfuromonas acetoxidans DSM 684 Length = 320 Score = 49.6 bits (113), Expect = 6e-05 Identities = 39/146 (26%), Positives = 66/146 (45%), Gaps = 5/146 (3%) Query: 67 EFMTTTTDFPVIAQFAANNRDDFVDASKLVYPYVDG-VDLNCGCPQKWAMKDGYGCSLLS 125 E + D P++ Q + + +A+++V V+LN GCP G ++L Sbjct: 61 EILAGVDDVPLVVQLIGHRSESLAEAAQIVADLGGAHVNLNMGCPFGRTTTGKTGGAMLQ 120 Query: 126 KPEIIYDIVKGLRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHCT- 183 +PE I D ++ +R S+SVK+R +D ++ L EK GV F+ Sbjct: 121 EPEKIGDCLRAIRAAFHG--SVSVKVRAGYDDPEQIFDLLPVFEKYGVDFIVLHPRTVVQ 178 Query: 184 KSSGPVDINGLKEVREALSVPMVANG 209 K + D V A ++P++ANG Sbjct: 179 KYADDADHAVTARVVAATALPVIANG 204 >UniRef50_Q9V0Y6 Cluster: Dihydroorotate dehydrogenase; n=8; Euryarchaeota|Rep: Dihydroorotate dehydrogenase - Pyrococcus abyssi Length = 303 Score = 49.6 bits (113), Expect = 6e-05 Identities = 39/178 (21%), Positives = 79/178 (44%), Gaps = 23/178 (12%) Query: 62 KARANEFMTTTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGC 121 +A EF DFPVI ++F ++ + D +LN CP GYG Sbjct: 81 EAFLEEFRKEKFDFPVIVSIFGGTPEEFAFLAEKLGEVADAFELNLSCPH----AKGYGM 136 Query: 122 SLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEH 181 + KPE +Y++VK +++V +K I+ ++DI++ + ++ GV+ + +++ Sbjct: 137 EIGQKPENVYEVVKAVKDV-TDKPVIAKLTPNVSDIRELGLAAEKAGADGVSAINTVKAI 195 Query: 182 C-----------TKSSG-------PVDINGLKEVREALSVPMVANGGVKHLNDATTYM 221 K G P+ + + ++ +L +P++ GG+ DA ++ Sbjct: 196 AIDIYAKRPILSNKFGGYSGPGVKPIALRAVYDLASSLDIPVIGIGGITTWQDAVEFL 253 >UniRef50_Q7UXK8 Cluster: Putative uncharacterized protein; n=3; Planctomycetaceae|Rep: Putative uncharacterized protein - Rhodopirellula baltica Length = 374 Score = 49.2 bits (112), Expect = 8e-05 Identities = 36/133 (27%), Positives = 58/133 (43%), Gaps = 3/133 (2%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTD--FPVIAQ 80 V A + YS + R + R +A ++L +K D PV Q Sbjct: 41 VQAALSGYSDLPMRVIARRHSASYTICEVMLDQFLLSLTKREKTRHFLDIADEEHPVGGQ 100 Query: 81 FAANNRDDF-VDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139 + F A KLV D +D+N GCP K + G LS+P + +I++ R+ Sbjct: 101 LMGAEPEQFSAGALKLVEAGFDVIDVNFGCPVKKVLGRCRGGFHLSQPAVAIEILRRTRD 160 Query: 140 VLPNKFSISVKIR 152 V+P+ ++VK+R Sbjct: 161 VVPDHIPVTVKMR 173 >UniRef50_Q6M9N8 Cluster: Putative uncharacterized protein; n=1; Candidatus Protochlamydia amoebophila UWE25|Rep: Putative uncharacterized protein - Protochlamydia amoebophila (strain UWE25) Length = 297 Score = 49.2 bits (112), Expect = 8e-05 Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 7/141 (4%) Query: 76 PVIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134 P+ Q + A+K++ D VDLNCGCP KDG G LL PE+I +IV Sbjct: 26 PIGGQLCGSKPSIAGQAAKIIEELGFDIVDLNCGCPVDKITKDGSGSGLLKTPELIGEIV 85 Query: 135 KGLRNVLPNKFSISVKIRLLNDIKKTVI--LCQQLEKCGVTFLTSMEEHCTKS-SGPVDI 191 + + + K ++VKIR D ++ + + Q +E+ G + + GP + Sbjct: 86 CNMVSAV--KIPVTVKIRAGWDEQQIQVENIVQIVEQAGAQAICIHGRTRQQGYRGPANW 143 Query: 192 NGLKEVR-EALSVPMVANGGV 211 +K + A S+ ++ NG V Sbjct: 144 EYIKRGKLAAKSIKIIGNGDV 164 >UniRef50_A6EDJ3 Cluster: Probable TIM-barrel protein, NifR3 family; n=1; Pedobacter sp. BAL39|Rep: Probable TIM-barrel protein, NifR3 family - Pedobacter sp. BAL39 Length = 335 Score = 49.2 bits (112), Expect = 8e-05 Identities = 39/200 (19%), Positives = 84/200 (42%), Gaps = 4/200 (2%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 APM S FR + + D+ +T I ++ +++ + + P+ Q + Sbjct: 18 APMEDVSDPPFRFVCKQSGVDMMYTEFISSEGLIRDAAKSRAKLDIFEYERPIGIQIFGS 77 Query: 85 NRDDFVDASKLV-YPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143 D +A+++ D +D+N GCP K G G +LL + + ++ K + N Sbjct: 78 EIDHMREATEIASMAGPDLMDINYGCPVKQVACRGAGSALLQDIDKMVEMTKAVVNATHL 137 Query: 144 KFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE--A 200 ++ ++ ++ K + ++L+ G+ LT G D ++E++ Sbjct: 138 PVTVKTRLGWDDNTKNVEEVAERLQDIGIQGLTIHGRTRAQMYKGEADWTLIREIKRNPR 197 Query: 201 LSVPMVANGGVKHLNDATTY 220 + +P+ NG V + A + Sbjct: 198 IKIPIFGNGDVDSIQKAADW 217 >UniRef50_Q9FI41 Cluster: Emb|CAB87804.1; n=7; Magnoliophyta|Rep: Emb|CAB87804.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 387 Score = 49.2 bits (112), Expect = 8e-05 Identities = 29/110 (26%), Positives = 54/110 (49%), Gaps = 5/110 (4%) Query: 25 APMVRYSKVHFRTLVRNFNADL-CFTPMILADSFCQNSKARANEFMTTTTD-FPVIAQFA 82 APM+ ++ H+RTL R +T M+ A++ + F+ + D P++ Q Sbjct: 15 APMMGWTDNHYRTLARLITKHAWLYTEMLAAETIVYQED-NLDSFLAFSPDQHPIVLQIG 73 Query: 83 ANNRDDFVDASKLVYPYV-DGVDLNCGCPQ-KWAMKDGYGCSLLSKPEII 130 N ++ A++L Y D ++ NCGCP K + + +G L+ P+ + Sbjct: 74 GRNLENLAKATRLANAYAYDEINFNCGCPSPKVSGRGCFGALLMLDPKFV 123 >UniRef50_Q0F181 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3; n=1; Mariprofundus ferrooxydans PV-1|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 - Mariprofundus ferrooxydans PV-1 Length = 341 Score = 48.8 bits (111), Expect = 1e-04 Identities = 38/191 (19%), Positives = 77/191 (40%), Gaps = 2/191 (1%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 V APM + + FR + + F L T MI + + + + PV Q A Sbjct: 21 VLAPMAGITDLPFRRICKRFGVGLMVTEMIASRAVDMGRERTERMAELGDDEHPVSIQIA 80 Query: 83 ANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141 ++ + +A++ + D VD+N GCP K K G ++L ++ ++ + + Sbjct: 81 GSDPEFVTEAARWAVGHGADFVDINMGCPVKKICKQVAGSAMLRDEALVARVLAAVVAAV 140 Query: 142 PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREA 200 ++ ++ + K + + E G+ LT G + + A Sbjct: 141 DVPVTLKIRTGWDDQSKNVQNIARIAEDSGIQLLTVHGRTRAQMFHGHACWEDIGLAKAA 200 Query: 201 LSVPMVANGGV 211 +S+P++ NG + Sbjct: 201 VSIPVIGNGDI 211 >UniRef50_Q04VP3 Cluster: TRNA-dihydrouridine synthase; n=4; Leptospira|Rep: TRNA-dihydrouridine synthase - Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197) Length = 339 Score = 48.8 bits (111), Expect = 1e-04 Identities = 39/157 (24%), Positives = 71/157 (45%), Gaps = 7/157 (4%) Query: 15 KINKTYLKVCAPMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTT 73 KI K Y APM+ + HFR +R + +T MI + + R + + Sbjct: 7 KIPKRYPVSLAPMMDRTDRHFRYFLRLISKHTFLYTEMIHTGAILHGDRRRFLSY--SPE 64 Query: 74 DFPVIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYD 132 + P+ Q +N ++SK+ Y ++LN GCP + +G L+ PE + + Sbjct: 65 ELPLAIQLGGDNPKALAESSKIGEDYGYSEINLNVGCPSDRVREGNFGACLMETPERVAE 124 Query: 133 IVKGLRNVLPNKFSISVKIRLLNDIKKTV-ILCQQLE 168 +V + + ++VK R+ K+T+ LC+ +E Sbjct: 125 LVCAMDGNV--SIPVTVKCRIGISGKETLEDLCRFIE 159 >UniRef50_A5EVV4 Cluster: Dihydrouridine synthase; n=1; Dichelobacter nodosus VCS1703A|Rep: Dihydrouridine synthase - Dichelobacter nodosus (strain VCS1703A) Length = 318 Score = 48.8 bits (111), Expect = 1e-04 Identities = 44/192 (22%), Positives = 82/192 (42%), Gaps = 7/192 (3%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILA-DSFCQNSKARANEFMTTTTDFPVIAQFAA 83 APM S + +R+L + F + M+ A F +++ FP I Q Sbjct: 17 APMAGISDLPYRSLCQRFGSHYTIAEMVDARPQFLAMPESQLRLQFDDDARFPKIVQLVG 76 Query: 84 NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 + + ++++ D +D+N GCP K K G +LLS + I+ + V+ Sbjct: 77 GDPYLMAETAQVMQALGCDVIDINMGCPAKKVGKQNAGSALLSDLPQVEKILAQVTRVV- 135 Query: 143 NKFSISVKIRL-LNDIKKTV-ILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE 199 +++K RL N+ T+ + + E GV LT + +G + + V+ Sbjct: 136 -SIPVTLKTRLGFNEQTMTIETVAKIAENTGVAALTVHGRTRAQRFNGTAHYDEIGRVKA 194 Query: 200 ALSVPMVANGGV 211 S+P++ NG + Sbjct: 195 QTSLPIIVNGDI 206 >UniRef50_A4TZK1 Cluster: Dihydrouridine synthase, DuS; n=4; Proteobacteria|Rep: Dihydrouridine synthase, DuS - Magnetospirillum gryphiswaldense Length = 335 Score = 48.8 bits (111), Expect = 1e-04 Identities = 38/198 (19%), Positives = 88/198 (44%), Gaps = 3/198 (1%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 + APM + + R LV+ A L + MI + + + ++ + P+ Q A Sbjct: 21 ILAPMSGVTDMPCRRLVKRMGAGLVVSEMIASQAMIRANRQTMKMASNCAEEHPMSVQLA 80 Query: 83 ANNRDDFVDASKLVYPYVDGV-DLNCGCPQKWAMKDGYGCSLLSKPEIIY-DIVKGLRNV 140 + +A+++ + D+N GCP K G S L K EI+ +++ Sbjct: 81 GCEPEVMAEAARMNADRGAAIIDINMGCPVKKVAVKGEAGSALMKDEILAGQLMEATVRA 140 Query: 141 LPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVRE 199 + ++ ++ ++ L + ++ G+ +T + +G D +++V++ Sbjct: 141 VDVPVTLKCRMGWDHNRLNAPRLARIAQESGIKMVTIHGRTRQQFYTGTADWKFVRQVKD 200 Query: 200 ALSVPMVANGGVKHLNDA 217 A+ +P++ NG ++ ++DA Sbjct: 201 AVDIPVIVNGDIETIDDA 218 >UniRef50_A1AW94 Cluster: TIM-barrel protein, yjbN family; n=1; Candidatus Ruthia magnifica str. Cm (Calyptogena magnifica)|Rep: TIM-barrel protein, yjbN family - Ruthia magnifica subsp. Calyptogena magnifica Length = 322 Score = 48.8 bits (111), Expect = 1e-04 Identities = 27/133 (20%), Positives = 62/133 (46%), Gaps = 4/133 (3%) Query: 25 APMVRYSKVHFRTLVRNFNADL-CFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83 APM+ ++ H R R + ++ +T M+ A + +K R +F + P++ Q Sbjct: 10 APMMDWTDRHCRYFYRLISKNVQLWTEMVTARAILYGNKNRLLDF--NVCEHPLVLQLGG 67 Query: 84 NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 + + A+K+ + + +++N GCP +G L+ P+++ V +R ++ Sbjct: 68 SEPKEMAQAAKIAQDWGYNEININVGCPSNRVQSSNFGVCLMQTPQVVAQCVDAMRQMVD 127 Query: 143 NKFSISVKIRLLN 155 ++ +I + N Sbjct: 128 VPITVKSRIGVDN 140 >UniRef50_Q5HJT5 Cluster: Probable tRNA-dihydrouridine synthase; n=41; Bacilli|Rep: Probable tRNA-dihydrouridine synthase - Staphylococcus aureus (strain COL) Length = 328 Score = 48.8 bits (111), Expect = 1e-04 Identities = 36/135 (26%), Positives = 61/135 (45%), Gaps = 7/135 (5%) Query: 23 VCAPMVRYSKVHFRTLVRNF-NADLCFTPMILADSFCQNSKARANEFMTTTTDF--PVIA 79 + APM + + FR +V D+ FT +SFC + T ++ P++A Sbjct: 15 ILAPMEDVTDIVFRHVVSEAARPDVFFTEFTNTESFCHPEGIHSVRGRLTFSEDEQPMVA 74 Query: 80 QFAANNRDDFVDAS-KLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLR 138 + + F + S +L G+DLN GCP K G G L+ +P++ +I++ + Sbjct: 75 HIWGDKPEQFRETSIQLAKMGFKGIDLNMGCPVANVAKKGKGSGLILRPDVAAEIIQATK 134 Query: 139 NVLPNKFSISVKIRL 153 +SVK RL Sbjct: 135 ---AGGLPVSVKTRL 146 >UniRef50_A1IF01 Cluster: Dihydrouridine synthase family protein; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Dihydrouridine synthase family protein - Candidatus Desulfococcus oleovorans Hxd3 Length = 326 Score = 48.4 bits (110), Expect = 1e-04 Identities = 38/197 (19%), Positives = 78/197 (39%), Gaps = 2/197 (1%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 + AP+ + FR L + L ++ M+ + S+ TT + P Q Sbjct: 13 ILAPLAGITDAPFRRLAKAAGCALVYSEMVSSHGLFYQSEKTGAMLRTTPEEAPFAVQIF 72 Query: 83 ANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141 A+ +V +D+N GC K +K G G +L+ + ++++ +R+ + Sbjct: 73 GGKPAVMGRAAAMVQASGAHMIDINFGCSVKKILKSGAGAALMKDLPLAAEVIQAVRDAV 132 Query: 142 PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVREA 200 +I ++ D L + E GV + T+ G D + + +++ Sbjct: 133 SIPLTIKMRSGWNPDGSDAFHLAEIAEARGVNAVALHPRTATQGFGGTADWSLIAALKQR 192 Query: 201 LSVPMVANGGVKHLNDA 217 +P++ NG + DA Sbjct: 193 TGLPVIGNGDIVLPEDA 209 >UniRef50_Q7X346 Cluster: Putative uncharacterized protein; n=1; uncultured Acidobacteria bacterium|Rep: Putative uncharacterized protein - uncultured Acidobacteria bacterium Length = 355 Score = 48.0 bits (109), Expect = 2e-04 Identities = 48/193 (24%), Positives = 80/193 (41%), Gaps = 13/193 (6%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP----VIAQ 80 APM + S + +R L A + + M LA + K + N FP Q Sbjct: 2 APMTKGSNLPYRRLCVELGARITVSEMTLA----RRLKQKRNSEFALIRRFPGEPCFGVQ 57 Query: 81 FAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139 A N D+ A+ LV D VD+N GCP + + G G S+ +P+ + +V+ ++ Sbjct: 58 LAGNKPDETAWAAALVESRGADFVDINFGCPIDYFTRKGLGASIGRQPQRMRRLVEAIKG 117 Query: 140 VLPNKFSISVKIRL-LNDIKKTVILCQQLEKCG--VTFLTSMEEHCTKSSGPVDINGLKE 196 + N ++ KIRL ND + + Q G + D + + Sbjct: 118 SVTN-IPVTAKIRLGWNDDDRNYLQQAQAAVDGGAAALFVHGRTRNARYRFAADWDAIAR 176 Query: 197 VREALSVPMVANG 209 + A+ VP++ NG Sbjct: 177 IVAAVPVPVIGNG 189 >UniRef50_UPI0000DAE45A Cluster: hypothetical protein Rgryl_01000346; n=1; Rickettsiella grylli|Rep: hypothetical protein Rgryl_01000346 - Rickettsiella grylli Length = 330 Score = 47.6 bits (108), Expect = 2e-04 Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 5/135 (3%) Query: 25 APMVRYSKVHFRTLVRNF--NADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 APM+ ++ H+ R A L +T M A + + S AR + + Q Sbjct: 15 APMLGWTTRHYHYFFRLICKKAQL-YTEMFTAQAILK-SPARERLLTVDANEKALAIQLG 72 Query: 83 ANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141 D A+K+V Y ++LN GCP + G+G LL +P + D + ++ V+ Sbjct: 73 GGIASDLSKAAKIVESYGYSEINLNVGCPSEKVQSGGFGVVLLKEPNRVADAIAAMKAVV 132 Query: 142 PNKFSISVKIRLLND 156 ++ +I + ND Sbjct: 133 RLPVTVKTRIGVDND 147 >UniRef50_Q2RZL4 Cluster: NifR3 family enzyme; n=1; Salinibacter ruber DSM 13855|Rep: NifR3 family enzyme - Salinibacter ruber (strain DSM 13855) Length = 443 Score = 47.6 bits (108), Expect = 2e-04 Identities = 43/190 (22%), Positives = 78/190 (41%), Gaps = 6/190 (3%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 APM S FR L + + AD+ +T + + + + + + P+ Q Sbjct: 80 APMEDVSDPPFRILCKRYGADMMYTEFVSSAGLLREQEHEHQKLEIFDEERPIGIQVWGG 139 Query: 85 NRDDFVDASKLVYPY-VDGVDLNCGCP-QKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 D+ +A+ +V D +D+N GCP +K KDG G +L + + +I + Sbjct: 140 GIDEVRNATPMVDAAGPDVIDINFGCPVRKIVQKDG-GAGVLRNLDKMRNITAAVMEEAT 198 Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE-- 199 ++ ++ +D V + + LE GV LT K G L+ ++E Sbjct: 199 RPVTVKTRLGWDDDSIHIVDVARMLEDMGVAALTVHARTREQKYKGDARWEWLRTIKEEG 258 Query: 200 ALSVPMVANG 209 +P + NG Sbjct: 259 TRDMPFIGNG 268 >UniRef50_Q7UBC5 Cluster: tRNA-dihydrouridine synthase A; n=231; Bacteria|Rep: tRNA-dihydrouridine synthase A - Shigella flexneri Length = 330 Score = 47.6 bits (108), Expect = 2e-04 Identities = 45/215 (20%), Positives = 94/215 (43%), Gaps = 22/215 (10%) Query: 25 APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83 APM+ ++ H R +R + + L +T M+ + + + + + PV Q Sbjct: 16 APMLDWTDRHCRYFLRLLSRNTLLYTEMVTTGAIIHG---KGDYLAYSEEEHPVALQLGG 72 Query: 84 NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 ++ +KL D ++LN GCP +G L+ +++ D VK +R+V+ Sbjct: 73 SDPAALAQCAKLAEARGYDEINLNVGCPSDRVQNGMFGACLMGNAQLVADCVKAMRDVV- 131 Query: 143 NKFSISVKIRL-LNDIKKTVILCQQLE------KCGV-------TFLTSMEEHCTKSSGP 188 ++VK R+ ++D LC + +C + +L+ + + P Sbjct: 132 -SIPVTVKTRIGIDDQDSYEFLCDFINTVSGKGECEMFIIHARKAWLSGLSPKENREIPP 190 Query: 189 VDINGLKEV-REALSVPMVANGGVKHLNDATTYMK 222 +D + ++ R+ + M NGG+K L +A +++ Sbjct: 191 LDYPRVYQLKRDFPHLTMSINGGIKSLEEAKAHLQ 225 >UniRef50_Q2NEG1 Cluster: PyrD; n=1; Methanosphaera stadtmanae DSM 3091|Rep: PyrD - Methanosphaera stadtmanae (strain DSM 3091) Length = 306 Score = 47.2 bits (107), Expect = 3e-04 Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 6/101 (5%) Query: 76 PVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVK 135 PVIA ++ + F D + YVD +LN CP K G+G ++ PE+ +DIV Sbjct: 94 PVIASIYGDSEEVFSDVANQTKDYVDAFELNVSCPH---AKCGFGSNIGENPELTHDIVS 150 Query: 136 GLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176 +++ N + + ++L ++ + + E G LT Sbjct: 151 SVKD---NIKDVPIIVKLTPNVTDITEIAKAAEDAGADALT 188 >UniRef50_Q2IG49 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3; n=2; Anaeromyxobacter|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 - Anaeromyxobacter dehalogenans (strain 2CP-C) Length = 352 Score = 46.8 bits (106), Expect = 4e-04 Identities = 38/195 (19%), Positives = 75/195 (38%), Gaps = 2/195 (1%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 AP+ S FR + R A +T M+ A + ++ + P Q A+ Sbjct: 15 APLAGVSDRPFRAICRRMGASFAYTEMVSAHGLMHGALQTSSYLDREPDEDPFAVQIFAS 74 Query: 85 NRDDFVDASKLVYPYVDG-VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143 D + + G +D+N CP K G G ++ P + + V+ +R +P Sbjct: 75 EPDVLARGAVVAVQAGAGMIDVNMACPVKKVCGSGAGAAMGRDPRKVEEAVRAIRAAVPV 134 Query: 144 KFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREALS 202 ++ ++ V + + E G + SG ++ V++A++ Sbjct: 135 PVTVKIRAGWDEGEVNCVDVARAAEAGGAAAVALHGRTRSQLYSGKARWELVRAVKQAVA 194 Query: 203 VPMVANGGVKHLNDA 217 +P++ +G V DA Sbjct: 195 IPVLGSGDVWTAGDA 209 >UniRef50_Q4Q231 Cluster: Dihydrouridine synthase domain protein-like protein; n=3; Leishmania|Rep: Dihydrouridine synthase domain protein-like protein - Leishmania major Length = 455 Score = 46.8 bits (106), Expect = 4e-04 Identities = 15/51 (29%), Positives = 35/51 (68%) Query: 100 VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVK 150 +DG+D+N GCP+K+++ +G+G +L+ +PE+ IV+ + + + ++ + Sbjct: 144 IDGIDINMGCPKKFSVHNGFGAALMKRPEVGGAIVRAVHGAVNSDSNVEAR 194 >UniRef50_A1AT39 Cluster: Dihydrouridine synthase, DuS; n=7; Desulfuromonadales|Rep: Dihydrouridine synthase, DuS - Pelobacter propionicus (strain DSM 2379) Length = 342 Score = 46.4 bits (105), Expect = 6e-04 Identities = 44/194 (22%), Positives = 78/194 (40%), Gaps = 7/194 (3%) Query: 25 APMVRYSKVHFRTLVRNF-NADLCFTPMILADSFCQNSKARANEFMTTTT---DFPVIAQ 80 APM + R+L ++ D+ FT + + + A + + D P++ Q Sbjct: 39 APMQGVTNSALRSLFIDWVRPDVVFTEFMRVNPAAAQRRLSAADLAEAGSAGDDVPLVVQ 98 Query: 81 FAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139 + R+ V S+ ++LN GCP G +L P+ + I+ LR Sbjct: 99 LIGHGREALVSGSQAAQDAGAAHINLNMGCPYGRMTSGQTGGGMLRSPQELSSIIPALRK 158 Query: 140 VLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVR 198 + FSI ++ N ++ L E GV FL K +G D E Sbjct: 159 TIRGTFSIKLRSGYDNP-RQIFDLLPLFEASGVDFLVLHPRTVLQKYAGFADHGITAEAV 217 Query: 199 EALSVPMVANGGVK 212 + ++P++ANG ++ Sbjct: 218 QRSTLPIIANGDIR 231 >UniRef50_Q06053 Cluster: tRNA-dihydrouridine synthase 3; n=6; Saccharomycetales|Rep: tRNA-dihydrouridine synthase 3 - Saccharomyces cerevisiae (Baker's yeast) Length = 609 Score = 46.0 bits (104), Expect = 7e-04 Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 5/135 (3%) Query: 22 KVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVI-AQ 80 K+ +P+ + +R L+R AD+ ++ M LA Q + + T++FP Q Sbjct: 295 KIVSPLTTVGNLPYRRLMRKLGADVTYSEMALAVPLIQGTNSEWALPKAHTSEFPGFGVQ 354 Query: 81 FAANNRDDFVDASKLV---YPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGL 137 A + A++ + + ++LN GCP + G G +LL P + + + Sbjct: 355 VACSKAWQAAKAAEALANSVSEISEINLNSGCPIDLLYRQGSGSALLDNPARMIRCLNAM 414 Query: 138 RNVLPNKFSISVKIR 152 N + I+VKIR Sbjct: 415 -NYVSKDIPITVKIR 428 >UniRef50_Q5ZVH8 Cluster: Zinc binding TIM barrel protein, YjbN family; n=4; Legionella pneumophila|Rep: Zinc binding TIM barrel protein, YjbN family - Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM 7513) Length = 334 Score = 45.6 bits (103), Expect = 0.001 Identities = 31/142 (21%), Positives = 63/142 (44%), Gaps = 4/142 (2%) Query: 16 INKTYLKVC-APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTD 74 +N + K+ APM+ ++ FRTL+R + + QN+ RA F + + Sbjct: 6 VNSIFSKLSIAPMIDWTNSPFRTLMRLLAPNALLYTEMQTTGAVQNNPDRALYF--NSVE 63 Query: 75 FPVIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDI 133 P+ Q ++ V + + + ++LN GCP +G L+ +PE + D Sbjct: 64 HPLAIQLGGADKSALVKCAIIAEQKGFNEINLNLGCPSDKVQAGRFGACLMKEPEHVADC 123 Query: 134 VKGLRNVLPNKFSISVKIRLLN 155 ++ ++ V+ + +I + N Sbjct: 124 IRAIKQVVGIPVTAKTRIGIDN 145 >UniRef50_Q8SUY1 Cluster: Putative uncharacterized protein ECU07_1170; n=1; Encephalitozoon cuniculi|Rep: Putative uncharacterized protein ECU07_1170 - Encephalitozoon cuniculi Length = 357 Score = 45.6 bits (103), Expect = 0.001 Identities = 28/112 (25%), Positives = 54/112 (48%), Gaps = 3/112 (2%) Query: 25 APMVRYSKVHFRTLVR-NFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83 APM+ + HFR +R + FT MI++++ + + E + D V+ Q Sbjct: 18 APMMDVTTAHFRRFIRLTSEKTVLFTEMIVSNTVIHVPRDKLRERLGEYDDRTVV-QIGG 76 Query: 84 NNRDDFVDASKLVYPYVDGV-DLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134 ++ V+A +++ + +LNCGCP K +G L+ E++ +I+ Sbjct: 77 SDATSMVEAVRILQGLGYRMFNLNCGCPSSRVKKGSFGAVLMLNRELVAEII 128 >UniRef50_Q6AJ40 Cluster: Putative uncharacterized protein; n=1; Desulfotalea psychrophila|Rep: Putative uncharacterized protein - Desulfotalea psychrophila Length = 318 Score = 44.8 bits (101), Expect = 0.002 Identities = 25/89 (28%), Positives = 43/89 (48%), Gaps = 1/89 (1%) Query: 76 PVIAQFAANNRDDFVD-ASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134 PVI Q NN +DF+ A +L ++ N GCP K G +L+ P++I + + Sbjct: 64 PVIPQLLHNNAEDFIALAGRLAELGYKEINWNLGCPAPMVAKKKRGSGMLAHPDLIVEFL 123 Query: 135 KGLRNVLPNKFSISVKIRLLNDIKKTVIL 163 + + +P K SI ++ N + +L Sbjct: 124 EEVLPQIPVKLSIKTRLGYSNTAQTKELL 152 >UniRef50_A5GPV9 Cluster: TRNA-dihydrouridine synthase A; n=21; Cyanobacteria|Rep: TRNA-dihydrouridine synthase A - Synechococcus sp. (strain RCC307) Length = 335 Score = 44.8 bits (101), Expect = 0.002 Identities = 28/115 (24%), Positives = 56/115 (48%), Gaps = 4/115 (3%) Query: 25 APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83 APM+ Y+ HFR ++R + L +T M++A + + F + P+ Q Sbjct: 19 APMMDYTDRHFRVVMRQVSRHALLYTEMVVAQALHHGRQDTLLGF--DPLEKPIALQLGG 76 Query: 84 NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGL 137 ++ +A++L + D ++LN GCP K +G L+++P+ + V+ + Sbjct: 77 DDPALLAEAAELAERWGYDEINLNVGCPSPKVKKGRFGACLMAEPQQVARCVEAM 131 >UniRef50_A0EAZ6 Cluster: Chromosome undetermined scaffold_87, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_87, whole genome shotgun sequence - Paramecium tetraurelia Length = 346 Score = 44.8 bits (101), Expect = 0.002 Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 6/133 (4%) Query: 25 APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMT--TTTDFPVIAQF 81 APM+ + HFR R + + +T MI ++ + + + + + PV+ Q Sbjct: 12 APMIDITYEHFRVFFRLLTKNCVLYTEMIHENAINLSRVLKPFPLVLDYSQVEHPVVCQL 71 Query: 82 AANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140 N+ + A+++ D ++LN GCP + +G L+ +P ++ +K ++ Sbjct: 72 GGNDPEKLAKAAQIAEQAGFDEINLNVGCPSERVQDGAFGACLMKEPHLVAQCMKKMKEA 131 Query: 141 LPNKFSISVKIRL 153 + K ++K RL Sbjct: 132 V--KIPCTLKCRL 142 >UniRef50_O31546 Cluster: Probable tRNA-dihydrouridine synthase 2; n=10; Bacilli|Rep: Probable tRNA-dihydrouridine synthase 2 - Bacillus subtilis Length = 325 Score = 44.8 bits (101), Expect = 0.002 Identities = 36/135 (26%), Positives = 62/135 (45%), Gaps = 7/135 (5%) Query: 23 VCAPMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQ-NSKARANEFMTTTTDF-PVIA 79 V APM + V FR +V D+ FT ++S+C + K +T T D P++A Sbjct: 15 VLAPMEDVTDVVFRHVVSEAGRPDVFFTEFTNSESYCHPDGKDSVRGRLTFTEDEQPIVA 74 Query: 80 QFAANNRDDFVDAS-KLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLR 138 + ++F S + G+D+N GCP +G G L+ +P + ++++ + Sbjct: 75 HIWGDKPENFRKMSIGMAELGFKGLDINMGCPVPNVAGNGKGSGLICRPAVAAELIQAAK 134 Query: 139 NVLPNKFSISVKIRL 153 +SVK RL Sbjct: 135 ---AGGLPVSVKTRL 146 >UniRef50_UPI000058804E Cluster: PREDICTED: similar to MGC53781 protein; n=3; Deuterostomia|Rep: PREDICTED: similar to MGC53781 protein - Strongylocentrotus purpuratus Length = 655 Score = 44.4 bits (100), Expect = 0.002 Identities = 39/200 (19%), Positives = 81/200 (40%), Gaps = 4/200 (2%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 AP+ + FR + + AD+ M + + Q + ++ Q Sbjct: 287 APLTTVGNLPFRAVCKKLGADITCGEMAMCTNLLQGQSSEWALLRRHPSEDIFGVQLCGG 346 Query: 85 NRDDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 D ++L+ +D +D+N GCP G G L+++ +IV+G+ +VL Sbjct: 347 FPDTMTRCAELLNDRLDIDFIDINVGCPIDLVYHKGAGSGLMNRMGKFQEIVRGMSSVLD 406 Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKE-VREA 200 ++ ++ + ND + +++ G + +T + S D + LK+ V+ A Sbjct: 407 IPLTVKMRTGVHNDNPVAHKIVRRIYDWGASVVTVHGRTREQRYSKLADWDYLKDCVQAA 466 Query: 201 LSVPMVANGGVKHLNDATTY 220 P + NG + D+ + Sbjct: 467 DPHPFIGNGDILSYEDSNFF 486 >UniRef50_Q2RTR9 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3; n=1; Rhodospirillum rubrum ATCC 11170|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 - Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255) Length = 362 Score = 44.4 bits (100), Expect = 0.002 Identities = 42/203 (20%), Positives = 87/203 (42%), Gaps = 6/203 (2%) Query: 21 LKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDF----P 76 L + APM + FR L ++ L +T M+ + + + + + P Sbjct: 13 LIMLAPMAGVTDSPFRRLAHDYGCPLSWTEMVASRELLRERARGVDPRLGGGAEAGRAGP 72 Query: 77 VIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVK 135 Q A + +A++ V + +D+N GCP + + G +L+ + I++ Sbjct: 73 FAVQLAGCDPLIMAEAARRVEGAGAELIDINMGCPVRKVVGGLGGSALMRDLPLAARILE 132 Query: 136 GLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM-EEHCTKSSGPVDINGL 194 + + S+ +++ + + V L + E G++ LT G D + Sbjct: 133 AVVGAVTLPVSLKMRLGWDDASRNAVELARLAESAGISRLTVHGRTRAQMYDGRADWPAI 192 Query: 195 KEVREALSVPMVANGGVKHLNDA 217 V+ A+S+P++ANG V +L++A Sbjct: 193 GLVKRAVSLPVIANGDVTNLSEA 215 >UniRef50_A4RVX6 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 371 Score = 44.4 bits (100), Expect = 0.002 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 5/113 (4%) Query: 103 VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVI 162 +DLNCGCP G G SLL PE +Y VK + + V ++L + + + Sbjct: 95 IDLNCGCPANVVTGKGAGSSLLRDPEYVYACVKAVADGARGS-GAHVTMKLRSGYDDSSL 153 Query: 163 LCQQL---EKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREALSVPMVANGGV 211 L + L + G F++ SG + + ++ L +P++ NG V Sbjct: 154 LRENLLAAREAGARFVSLHARTRAQGYSGRANWEEIAFAKDVLDIPVLGNGDV 206 >UniRef50_Q9VIS4 Cluster: CG10463-PA; n=3; Sophophora|Rep: CG10463-PA - Drosophila melanogaster (Fruit fly) Length = 604 Score = 44.4 bits (100), Expect = 0.002 Identities = 46/202 (22%), Positives = 85/202 (42%), Gaps = 11/202 (5%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 V +P+ + FR + + F AD+ M A + ++ Q Sbjct: 260 VLSPLTTLGNLPFRRICKEFGADITCGEMACAQPLLKGMGQEWALTKRHQSEDVFGVQLC 319 Query: 83 ANNRDDFVDASKLVYP--YVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140 NN + A+++++ VD +DLN GCP + G G +L+ + I+ V+ Sbjct: 320 GNNPNMLNQAAQVIHETAQVDFIDLNIGCPIDLIYQQGGGSALMRRTNILELTVRSCA-A 378 Query: 141 LPNKFSISVKIRLLNDIKKTVI--LCQQLEKCGVTFLT----SMEEHCTKSSGPVDINGL 194 L ++ +VK+R K+V L +E+ G + +T S E+ TK + I Sbjct: 379 LSDRLPFTVKMRTGIYADKSVAHELLPLVEEWGASAVTLHGRSREQRYTKHANWAYIE-- 436 Query: 195 KEVREALSVPMVANGGVKHLND 216 + +A +P++ NG + D Sbjct: 437 ECAAKAKCMPVIGNGDILSYED 458 >UniRef50_Q7UKE8 Cluster: Putative uncharacterized protein; n=2; Planctomycetaceae|Rep: Putative uncharacterized protein - Rhodopirellula baltica Length = 364 Score = 44.0 bits (99), Expect = 0.003 Identities = 47/196 (23%), Positives = 83/196 (42%), Gaps = 11/196 (5%) Query: 25 APMVRYSKVHFRTLVRNF-NADLCFTPMILADSF--CQNSKARANEFMTTTTD--FPVIA 79 APM ++ FR +VR F A L T M+ A F ++A + + D P+ Sbjct: 33 APMAGFTNAAFRHIVRQFGGAGLLATEMVNARGFVWLDENEAEHPDRLWGVADEPRPLAV 92 Query: 80 QFAANNRDDFVDAS-KLVYPY-VDGVDLNCGCPQKWAMKDGY-GCSLLSKPEIIYDIVKG 136 Q N+ + +L Y V VD+N GCP + + + G LL +P ++ I+ Sbjct: 93 QIWDNDPETMAKVGRRLAEEYRVSVVDINFGCPVRQVTEKAHSGSYLLREPNRMHAIISR 152 Query: 137 LRNV-LPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGL 194 L V P + +++ + + + +E+ G LT G D + Sbjct: 153 LVQVCAPTPVTAKIRLGCSRENINCNEIARVVEEAGAAALTVHGRTAADMFRGNADWERI 212 Query: 195 KEVREAL-SVPMVANG 209 E++ L ++P++ NG Sbjct: 213 SEIKSHLRNIPLIGNG 228 >UniRef50_A1IED4 Cluster: Putative uncharacterized protein; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Putative uncharacterized protein - Candidatus Desulfococcus oleovorans Hxd3 Length = 324 Score = 44.0 bits (99), Expect = 0.003 Identities = 48/203 (23%), Positives = 85/203 (41%), Gaps = 9/203 (4%) Query: 21 LKVCAPMVRYSKVH-FRT-LVRNFNA-DLCFTPMILADSFCQNSKARANEFMTT-TTDFP 76 + +C +R H FRT +F D P + + + A + + T P Sbjct: 3 MTLCMAPIRGITDHIFRTAFAEHFGGFDTAVAPFVSSRKDRKIKSAHLKDLLPEYNTALP 62 Query: 77 VIAQFAANNRDDFVDASKLVYPYVDGV-DLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVK 135 V+ Q +N+ +DFV + +Y V + N GCP K G LL + I + + Sbjct: 63 VVPQILSNSGEDFVYLADHLYDLGYSVTNWNLGCPYPMVAKKYRGAGLLPHTDRIAEFLD 122 Query: 136 GLRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVT-FLTSMEEHCTKSSGPVDING 193 + + + K +SVKIRL D + + L L + + + + G VD+ Sbjct: 123 TVMSRM--KGGLSVKIRLGWADTTELMGLLPVLHRYPLAELIVHPRTGIQRYEGTVDLAA 180 Query: 194 LKEVREALSVPMVANGGVKHLND 216 + V E +P++ NG ++ + D Sbjct: 181 FERVLENTGLPVMYNGDIQTVAD 203 >UniRef50_Q01ML2 Cluster: H0613H07.1 protein; n=10; Eukaryota|Rep: H0613H07.1 protein - Oryza sativa (Rice) Length = 685 Score = 43.6 bits (98), Expect = 0.004 Identities = 34/154 (22%), Positives = 58/154 (37%), Gaps = 2/154 (1%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 AP+ + FR L + AD+ M + + Q + +++ Q Sbjct: 337 APLTTVGNLPFRRLCKTLGADITCGEMAMCTNLLQGQASEWALLRRHSSEDLFGVQICGA 396 Query: 85 NRDDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 D +LV VD +D+N GCP + G G SLL+KP I IV+ V Sbjct: 397 YPDTVARTVELVDNECSVDFIDINMGCPIDIVVNKGAGSSLLTKPMRIKSIVQAASTVTE 456 Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176 ++ V+ + + + G + +T Sbjct: 457 KPLTVKVRTAFFEGRNRADSIVSDIYDWGASAIT 490 >UniRef50_Q5FTP7 Cluster: Nitrogen assimilation regulatory protein NifR3; n=3; Acetobacteraceae|Rep: Nitrogen assimilation regulatory protein NifR3 - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 371 Score = 43.2 bits (97), Expect = 0.005 Identities = 42/201 (20%), Positives = 88/201 (43%), Gaps = 10/201 (4%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 + AP+ + + FR L R+ A L + MI + + + ++ P Q A Sbjct: 38 ILAPLSGVTDLPFRQLARDLGAGLVVSEMIASWAMIRENE-NTMRMARMAERGPNAVQLA 96 Query: 83 ANNRDDFVDASKLVYPYVDG----VDLNCGCP-QKWAMKDGYGCSLLSKPEIIYDIVKGL 137 + A+K+ VDG +D+N GCP +K A+ G +L+ + +++ Sbjct: 97 GCDPKAMAQAAKIS---VDGGANLIDINFGCPVKKVAIGQMAGSALMRDEVLAGKLLEAT 153 Query: 138 RNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM-EEHCTKSSGPVDINGLKE 196 + ++ +++ ++ L + E+ G+ +T +G D +K Sbjct: 154 ARAVNVPVTLKMRMGWDHNSLNAPRLAKIAEESGIRLVTVHGRTRQMFYNGTADWRFVKT 213 Query: 197 VREALSVPMVANGGVKHLNDA 217 V++A+S+P++ NG + + DA Sbjct: 214 VKDAVSLPVIVNGDINTIRDA 234 >UniRef50_A6PPM6 Cluster: Dihydrouridine synthase, DuS; n=1; Victivallis vadensis ATCC BAA-548|Rep: Dihydrouridine synthase, DuS - Victivallis vadensis ATCC BAA-548 Length = 343 Score = 43.2 bits (97), Expect = 0.005 Identities = 47/193 (24%), Positives = 81/193 (41%), Gaps = 9/193 (4%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84 AP+ ++ + +R R FT M+ S + A + + Q Sbjct: 21 APLSGFTDLPYRRAARAGGCRFAFTEMVDVASLTYARERSAGMLRRGPEEEFLGVQLVGA 80 Query: 85 NRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143 + + A+ +V Y VD N GCP K G G L + + + Sbjct: 81 DHEFIRRAADVVNEYEFSVVDFNLGCPVPKVAKKGAGAELGRHLDAALACFAIIAE--RS 138 Query: 144 KFSISVKIRLLN--DIKKTVILCQQLEKCGVTFLTSMEEHCTKS--SGPVDINGLKEVRE 199 + ++ KIR+++ D T+ L + L + G +T + ++ SGPV+ ++ VRE Sbjct: 139 RHPVTAKIRIVDAEDPAPTLALAKGLAELGAQAIT-VHGRIKEAFYSGPVNFGMIRAVRE 197 Query: 200 AL-SVPMVANGGV 211 AL V ++ANGGV Sbjct: 198 ALPGVQVIANGGV 210 >UniRef50_A5N517 Cluster: Predicted NADH oxidase; n=1; Clostridium kluyveri DSM 555|Rep: Predicted NADH oxidase - Clostridium kluyveri DSM 555 Length = 328 Score = 43.2 bits (97), Expect = 0.005 Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 11/113 (9%) Query: 116 KDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLN------DIKKTVILCQQLEK 169 +D YG + + +I DIVK +R + F I +++ + I+ + + QQLEK Sbjct: 186 QDEYGGDITGRIKIHRDIVKNVREAVGESFPIFMRLGASDYMDGGLTIEDSKLAAQQLEK 245 Query: 170 CGVTFLTSMEEHCTKSSGPVDINGL-----KEVREALSVPMVANGGVKHLNDA 217 GV L C + V+ G K ++E +S+P++ GG+ H A Sbjct: 246 TGVDVLDISGGLCRYTIPGVNEEGYFTPLSKAIKEVVSIPVIVTGGIIHAKTA 298 >UniRef50_Q2HDP2 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 641 Score = 43.2 bits (97), Expect = 0.005 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 4/78 (5%) Query: 79 AQFAANNRDDFVDASKLV---YPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVK 135 AQ AAN V A++ + P++ VDLNCGCP K G G +LL + +++ Sbjct: 311 AQIAANAPWVAVKATEALSQLLPHLRLVDLNCGCPVDAVFKSGSGSALLDSHSKLERMIR 370 Query: 136 GLRNVLPNKFSISVKIRL 153 G+ N + + I+ KIR+ Sbjct: 371 GM-NAVSGEVPITAKIRM 387 >UniRef50_A0Z3E6 Cluster: Dihydroorotate dehydrogenase/oxidoreductase, FAD-binding protein; n=5; Bacteria|Rep: Dihydroorotate dehydrogenase/oxidoreductase, FAD-binding protein - marine gamma proteobacterium HTCC2080 Length = 551 Score = 42.7 bits (96), Expect = 0.007 Identities = 27/111 (24%), Positives = 54/111 (48%), Gaps = 6/111 (5%) Query: 32 KVHFRTLVRNFNADLCFTPMI-LADSFCQNSKARANEFMTTTTDFPVIAQFAANNRDDFV 90 ++ +R V + A CF + L + S A + F +++ F + ++FV Sbjct: 51 RLGYREPVYSQFAPGCFVNAVGLTNPGAHASLASLGQLRVPEDRFLLVSIFGGSV-EEFV 109 Query: 91 DASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141 +K++ P DG +LN CP GYG ++ P+I+++I+ ++ V+ Sbjct: 110 AVAKILEPVADGFELNLSCPH----ASGYGMAMGQDPKIVHEIIAAVKQVV 156 >UniRef50_Q582L4 Cluster: TRNA-dihydrouridine synthase 3, putative; n=3; Trypanosoma|Rep: TRNA-dihydrouridine synthase 3, putative - Trypanosoma brucei Length = 528 Score = 42.7 bits (96), Expect = 0.007 Identities = 33/136 (24%), Positives = 61/136 (44%), Gaps = 8/136 (5%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82 V AP+ + FR + + + AD+ M + + + K+ + +++ Q A Sbjct: 169 VLAPLTTVGNLPFRRVCKEYGADITVGEMAIVHNLNRLQKSEWSLLRRHSSEDIFGLQIA 228 Query: 83 ANNRDDFVDASKLV----YPYVDGVDLNCGCPQKWAMKDGYGCSLLS-KPEIIYDIVKGL 137 + D + ++ V + Y D VD+NCGCP + G GC L K + D+V+ L Sbjct: 229 VSRPHDAITWAQAVEESGFSY-DFVDINCGCPVDKVVLSGCGCGLWERKGNRLRDVVQSL 287 Query: 138 RNVLPNKFSISVKIRL 153 V +++K R+ Sbjct: 288 --VAHQSKPVTIKCRM 301 >UniRef50_Q8A2H9 Cluster: Putative nifR3 family TIM-barrel enzyme with dihydrouridine synthase domain; n=6; Bacteroidales|Rep: Putative nifR3 family TIM-barrel enzyme with dihydrouridine synthase domain - Bacteroides thetaiotaomicron Length = 314 Score = 42.3 bits (95), Expect = 0.009 Identities = 37/119 (31%), Positives = 53/119 (44%), Gaps = 10/119 (8%) Query: 103 VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN--KFSISVKIRL-LNDIKK 159 VD+N GCP K G +L PE VK L +++ + S SVK+RL + Sbjct: 91 VDINLGCPFPLLAKRHNGSGILPYPEE----VKALLSIVTRYPQISFSVKMRLGWEQPDE 146 Query: 160 TVILCQQLEKCGVTFLTSMEEHCTKSS--GPVDINGLKEVREALSVPMVANGGVKHLND 216 + L L + +T M K G VD+ G RE +P+V NG + +L D Sbjct: 147 CLALAPILNDLPLRQIT-MHPRLGKQGYKGEVDLQGFSAFREVCQLPLVYNGDIHNLED 204 >UniRef50_Q83D40 Cluster: TIM-barrel protein, yjbN family; n=7; Bacteria|Rep: TIM-barrel protein, yjbN family - Coxiella burnetii Length = 353 Score = 41.9 bits (94), Expect = 0.012 Identities = 30/130 (23%), Positives = 58/130 (44%), Gaps = 6/130 (4%) Query: 25 APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83 APM+ + HFR +R + L +T M+ + + + R ++ + + P+ Q Sbjct: 34 APMMGCTDRHFRMFMRQISRHVLLYTEMVTTGALLKGKQWRCLDY--SPEEHPLALQVGG 91 Query: 84 NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 ++ ++L D ++LN GCP + +G LL + E++ D V + + Sbjct: 92 SDPQSLALCARLAEEKGFDEINLNVGCPSGRVIAGRFGACLLKEAELVADCVAAMSAEV- 150 Query: 143 NKFSISVKIR 152 +SVK R Sbjct: 151 -NIPVSVKTR 159 >UniRef50_A5FPW7 Cluster: Dihydroorotate dehydrogenase family protein; n=21; Bacteria|Rep: Dihydroorotate dehydrogenase family protein - Dehalococcoides sp. BAV1 Length = 324 Score = 41.9 bits (94), Expect = 0.012 Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 17/166 (10%) Query: 72 TTDFPVIAQFAANNRDDFVDASKLV--YPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129 T D PVI AA + +D+ + ++ + P V G+++N CP +G S S ++ Sbjct: 112 TWDVPVIVNIAAESIEDYAELARRLDKVPGVSGIEVNISCPNVKCGCIEFGSSPESAAKV 171 Query: 130 IYDIVKG------LRNVLPNKFSISVKIRLLNDIKKTVI-LCQQLEKCGVTFLTS---ME 179 D+V+ + + PN SI+ + + D I L L + + Sbjct: 172 T-DVVRNATTLPLIVKLTPNTSSITELAKAVADAGADAISLINTLRGMRIDIKKRRPVLG 230 Query: 180 EHCTKSSGP----VDINGLKEVREALSVPMVANGGVKHLNDATTYM 221 H SGP V I+ + +V A++VP++ GG+ + DA ++ Sbjct: 231 NHTGGLSGPAIKPVAISMVYQVAGAVNVPVIGGGGIMNAEDALEFL 276 >UniRef50_Q9UTH9 Cluster: tRNA dihydrouridine synthase Dus3; n=1; Schizosaccharomyces pombe|Rep: tRNA dihydrouridine synthase Dus3 - Schizosaccharomyces pombe (Fission yeast) Length = 617 Score = 41.9 bits (94), Expect = 0.012 Identities = 20/56 (35%), Positives = 33/56 (58%), Gaps = 1/56 (1%) Query: 100 VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLN 155 VD +DLNCGCP + G G SLL P + ++G+ + + + ++VK+R+ N Sbjct: 331 VDFLDLNCGCPIDLVFRQGAGSSLLENPGRLLRNLQGM-DAVSGQIPVTVKLRMGN 385 >UniRef50_A7DKP5 Cluster: Dihydrouridine synthase, DuS; n=2; Methylobacterium extorquens PA1|Rep: Dihydrouridine synthase, DuS - Methylobacterium extorquens PA1 Length = 354 Score = 41.5 bits (93), Expect = 0.016 Identities = 31/132 (23%), Positives = 58/132 (43%), Gaps = 8/132 (6%) Query: 25 APMVRYSKVHFRTLVRNFNADL-CFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83 APM+ ++ R R + +T M+ + + R F + P+ Q Sbjct: 33 APMMDWTDRQCRAFHRTLSRRARLYTEMVTTGAVLHGDRERLLGF--DAYEQPLAVQLGG 90 Query: 84 NNRDDFVDASKLV--YPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141 +N DD A+++ + Y + ++LN GCP +G L+ +P ++ V L+ + Sbjct: 91 SNPDDLAAAARIAADFGYAE-INLNVGCPSDRVQDGRFGACLMREPGLVGACVAALKAAV 149 Query: 142 PNKFSISVKIRL 153 P ++VK RL Sbjct: 150 P--VPVTVKCRL 159 >UniRef50_A4BWB1 Cluster: Putative uncharacterized protein; n=5; Bacteroidetes|Rep: Putative uncharacterized protein - Polaribacter irgensii 23-P Length = 317 Score = 41.1 bits (92), Expect = 0.021 Identities = 32/133 (24%), Positives = 59/133 (44%), Gaps = 6/133 (4%) Query: 25 APMVRYSKVHFRTLVRNF--NADLCFTPMI-LADSFCQNSKARANEFMTTTTDFPVIAQF 81 +P+ ++ FR +F D ++P I L + + + + ++ VI Q Sbjct: 8 SPLQGFTDYKFRNAFNHFFGGIDTFYSPYIRLNGKMVIKNSYQKDLLLENNSELEVIPQI 67 Query: 82 AANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140 N+ ++F+ SK V ++ N GCP K G G L+S E I I+ + N Sbjct: 68 ITNDAEEFLFVSKYVRALGYKELNWNLGCPYPMVTKRGMGSGLISDAEKINSILHKVHN- 126 Query: 141 LPNKFSISVKIRL 153 + +S+K+R+ Sbjct: 127 -ESDILVSMKMRM 138 >UniRef50_A7AWB5 Cluster: Dihydrouridine synthase (Dus) domain containing protein; n=1; Babesia bovis|Rep: Dihydrouridine synthase (Dus) domain containing protein - Babesia bovis Length = 362 Score = 41.1 bits (92), Expect = 0.021 Identities = 35/134 (26%), Positives = 59/134 (44%), Gaps = 8/134 (5%) Query: 25 APMVRYSKVHFRTLVRNFNADL-CFTPMILADSFCQNSKARANEFM-TTTTDFPVIAQFA 82 APM+ + FR +R +T M+ S + + + P++ Q Sbjct: 21 APMLDITYYEFRQFMRLITKRAQLWTEMMADGSLIYGDSDKVGSMLHCDANEHPIVLQLG 80 Query: 83 ANNRDDFVDASKLV--YPYVDGVDLNCGCPQ-KWAMKDGYGCSLLSKPEIIYDIVKGLRN 139 NN D A + Y Y + +LN GCP + + K +G +L++ ++ IVK LR+ Sbjct: 81 GNNLDSLSKAGNIALGYGYTE-FNLNVGCPSTRVSGKGCFGAALMNDAPLVGRIVKHLRS 139 Query: 140 VLPNKFSISVKIRL 153 L ++VK RL Sbjct: 140 ELGT--PVTVKHRL 151 >UniRef50_Q9PGB5 Cluster: tRNA-dihydrouridine synthase A; n=8; Proteobacteria|Rep: tRNA-dihydrouridine synthase A - Xylella fastidiosa Length = 340 Score = 41.1 bits (92), Expect = 0.021 Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 8/126 (6%) Query: 29 RYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAANNRDD 88 RY +V R L + +T M+ A + + R F + + PV Q + Sbjct: 29 RYCRVFHRVLAPSARL---YTEMVHAKAVIYGDRERLLGF--ASVEQPVALQLGGSEPAL 83 Query: 89 FVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSI 147 A+++ + ++LNCGCP +G L+ +P ++ D V + V+ + Sbjct: 84 LAKAARIAVDWGYSEINLNCGCPSDRVQAGSFGARLMREPALVADCVAAMAAVV--SVPV 141 Query: 148 SVKIRL 153 +VK RL Sbjct: 142 TVKCRL 147 >UniRef50_Q979G6 Cluster: Dihydroorotate dehydrogenase; n=4; Thermoplasmatales|Rep: Dihydroorotate dehydrogenase - Thermoplasma volcanium Length = 301 Score = 40.7 bits (91), Expect = 0.028 Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 9/95 (9%) Query: 76 PVIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134 P+I A N ++F S + Y VD ++LN CP G+G + S P+++ DIV Sbjct: 94 PIIGSVFAYNAEEFTKLSVKMEEYGVDAIELNLSCPHV----KGFGLEVGSDPDLVEDIV 149 Query: 135 KGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEK 169 N + +K + V +L ++ + + + EK Sbjct: 150 ----NEIKSKVKVPVFAKLSPNVSNIIEIAKAAEK 180 >UniRef50_Q38BB4 Cluster: TRNA-dihydrouridine synthase 2, putative; n=3; Trypanosoma|Rep: TRNA-dihydrouridine synthase 2, putative - Trypanosoma brucei Length = 435 Score = 40.3 bits (90), Expect = 0.037 Identities = 18/52 (34%), Positives = 29/52 (55%) Query: 76 PVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKP 127 PV+ Q A+ L VDG+D+N GCP+K+++ +G G +L+ P Sbjct: 95 PVVLQLGVAEPAIGARAALLCVDDVDGIDVNMGCPKKFSVDNGMGAALMRDP 146 >UniRef50_Q8G7W8 Cluster: Possible NifR3-like protein; n=4; Bifidobacterium|Rep: Possible NifR3-like protein - Bifidobacterium longum Length = 414 Score = 39.9 bits (89), Expect = 0.049 Identities = 49/203 (24%), Positives = 80/203 (39%), Gaps = 9/203 (4%) Query: 23 VCAPMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQF 81 V +PM + FR + + D L MI A + ++ ++ Q Sbjct: 50 VLSPMAGVTNWPFRVICEEYGPDGLYVAEMITARALVAHNPKALRLCHFAKSEKIRSLQL 109 Query: 82 AANNRDDFVDASKLVYP--YVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139 N A+K+V D VDLN GCP + G G +L K +I ++++ + Sbjct: 110 YGVNPSITEQAAKIVVDGNMADHVDLNFGCPVPKVTRRGGGSALPWKTDIFTELLQRVVA 169 Query: 140 VL-PNKFSISVKIRLLNDIKKTVIL----CQQLEKCGVTFLTSMEEHCTKSSGPVDINGL 194 V P ++ KIR+ D L Q E C L + G D + + Sbjct: 170 VCEPAGIPVTAKIRVGIDHNHETFLEAGHIAQEEGCKAVTLHA-RTTAEYYGGHSDWSRI 228 Query: 195 KEVREALSVPMVANGGVKHLNDA 217 E++E L++P+ NG + DA Sbjct: 229 GELKEHLNIPVFGNGDIWGAEDA 251 >UniRef50_Q0C0N1 Cluster: Putative tRNA-dihydrouridine synthase; n=1; Hyphomonas neptunium ATCC 15444|Rep: Putative tRNA-dihydrouridine synthase - Hyphomonas neptunium (strain ATCC 15444) Length = 345 Score = 39.9 bits (89), Expect = 0.049 Identities = 42/193 (21%), Positives = 79/193 (40%), Gaps = 9/193 (4%) Query: 25 APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPV---IAQF 81 APM + R +F A + M+ + +KARA+ T I Q Sbjct: 26 APMSGATDAPMRRQAVHFGAPAVVSEMVAGEML---AKARADVVRRTCRHEGAGYWIVQL 82 Query: 82 AANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV-KGLRN 139 AA +D + + L+ VD +D+N GCP K G +L+ + +I+ L+ Sbjct: 83 AARRPEDMLAGAVLMAEAGVDVIDINMGCPSKQVTGGQSGSALMRDLPLAGEIIDAALQG 142 Query: 140 VLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVR 198 ++ +++ ++ L + GV LT C +G + ++ Sbjct: 143 AAGRPVTLKMRLGWDDENLNAPELAVMAQDRGVQMLTVHGRTRCQFYTGGANWAAVRATV 202 Query: 199 EALSVPMVANGGV 211 +A+S+P++ NG + Sbjct: 203 DAVSLPVIVNGDI 215 >UniRef50_Q6C4K3 Cluster: Similar to DEHA0D12364g Debaryomyces hansenii; n=1; Yarrowia lipolytica|Rep: Similar to DEHA0D12364g Debaryomyces hansenii - Yarrowia lipolytica (Candida lipolytica) Length = 622 Score = 39.9 bits (89), Expect = 0.049 Identities = 34/139 (24%), Positives = 62/139 (44%), Gaps = 12/139 (8%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKAR------ANEFMTTTTDFP 76 + +P+ + +R L+++ AD+ + M L Q KA + +T F Sbjct: 250 IVSPLTTVGNLPYRRLMKDLGADVTYGEMALTLPLIQGHKAEWALTRCHSSEVTEGNHFG 309 Query: 77 VIAQFAANNRDDFVDASKLVYPYVDGV---DLNCGCPQKWAMKDGYGCSLLSKPEIIYDI 133 V Q A + A++ V G+ +LNCGCP + G G +L+ + I Sbjct: 310 V--QVTAPKHWQAIKAAQAVSELCTGISEINLNCGCPIDLVYRQGAGSALMDQQGKTARI 367 Query: 134 VKGLRNVLPNKFSISVKIR 152 V+G+ +++ I+VK+R Sbjct: 368 VRGM-SMVSGDVPITVKMR 385 >UniRef50_Q7PVV7 Cluster: ENSANGP00000016833; n=2; Endopterygota|Rep: ENSANGP00000016833 - Anopheles gambiae str. PEST Length = 594 Score = 39.5 bits (88), Expect = 0.065 Identities = 31/120 (25%), Positives = 58/120 (48%), Gaps = 11/120 (9%) Query: 100 VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN---KFSISVKIRLLND 156 VD +DLN GCP G G +LL + ++ +V+ +L + +F++ +I + N+ Sbjct: 327 VDFIDLNTGCPIDLIFNQGGGSALLRRQNVLKVMVQSCSRLLADYGKEFTVKTRIGIYNN 386 Query: 157 IKKTVILCQQLEKCGVTFLT----SMEEHCTKSSGPVDINGLKE-VREALSVPMVANGGV 211 + + E G + +T + E+ TK + D L++ +A SVP+ NG + Sbjct: 387 KLIAHEMVPKFEDWGASLITIHGRTKEQRYTKRA---DWEYLQQCATQAQSVPVFGNGDI 443 >UniRef50_Q9K9W1 Cluster: Dihydroorotate dehydrogenase; n=1; Bacillus halodurans|Rep: Dihydroorotate dehydrogenase - Bacillus halodurans Length = 305 Score = 39.5 bits (88), Expect = 0.065 Identities = 37/171 (21%), Positives = 80/171 (46%), Gaps = 31/171 (18%) Query: 74 DFPVIAQFAANNRDDFVDASKLV--YPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIY 131 D P++A A + +D+V+ ++ + V ++LN CP +K+G G + + P++ Sbjct: 93 DVPIVANIAGSTVNDYVEVAEAISRVDNVHALELNISCPN---VKEG-GIAFGTVPDVAA 148 Query: 132 DIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCG------VTFLTSMEEHCTKS 185 + + ++ V ++ V ++L ++ V + Q +E+ G + L M + Sbjct: 149 QLTQEVKRV----STVPVYVKLSPNVSDIVEMAQAVERAGADGLSMINTLLGMRLDLKRR 204 Query: 186 -----------SG----PVDINGLKEVREALSVPMVANGGVKHLNDATTYM 221 SG PV I + +V +A+S+P++ GG++ +D +M Sbjct: 205 TPILANGTGGLSGPAIKPVAIRMIYQVSQAVSIPIIGMGGIQSADDVLEFM 255 >UniRef50_Q73P17 Cluster: Dihydroorotate dehydrogenase/oxidoreductase, FAD-binding; n=1; Treponema denticola|Rep: Dihydroorotate dehydrogenase/oxidoreductase, FAD-binding - Treponema denticola Length = 591 Score = 39.1 bits (87), Expect = 0.085 Identities = 25/106 (23%), Positives = 51/106 (48%), Gaps = 4/106 (3%) Query: 73 TDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYD 132 TD + +A+N +DF+ K D +LN CP A G+G S+ P I + Sbjct: 106 TDSILNVSLSASNPEDFISLLKGFEELADCFELNFSCPHASA---GFGASIGCDPAIAAE 162 Query: 133 IVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM 178 VK ++ LP+ ++ + ++L +++ + + + G +T++ Sbjct: 163 YVKIIKKALPD-CAVPIFVKLTPNVEDIGAIASAVIEAGADGITAI 207 >UniRef50_Q090Q9 Cluster: TRNA-dihydrouridine synthase B; n=2; Cystobacterineae|Rep: TRNA-dihydrouridine synthase B - Stigmatella aurantiaca DW4/3-1 Length = 369 Score = 39.1 bits (87), Expect = 0.085 Identities = 26/107 (24%), Positives = 46/107 (42%), Gaps = 2/107 (1%) Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQ-NSKARANEFMTTTTDFPVIAQF 81 + APM S+ FR + + A LC T ++ A + N + + + P Q Sbjct: 46 ILAPMAGVSERPFRVIAFKWGAALCPTELVSAQGLMRANQRTLKYLRFSPEVERPYSLQI 105 Query: 82 AANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKP 127 + A+ + + +D+N GCP K K+G G +L+ +P Sbjct: 106 FGGEPEAMAQAALVGKAHGAQIIDINMGCPVKKVTKNGAGSALMCEP 152 >UniRef50_A6GGZ7 Cluster: Putative uncharacterized protein; n=2; Bacteria|Rep: Putative uncharacterized protein - Plesiocystis pacifica SIR-1 Length = 362 Score = 39.1 bits (87), Expect = 0.085 Identities = 28/131 (21%), Positives = 56/131 (42%), Gaps = 6/131 (4%) Query: 25 APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83 APM+ + HFR L+R L +T M+ + + + + + P+ Q Sbjct: 26 APMMDRTDRHFRRLMRLITRHTLLYTEMVTCPAVLHGDREHILGYHPS--EHPLALQLGG 83 Query: 84 NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142 ++ + +++ D V++N GCP +G L+ P + D V +R + Sbjct: 84 DDPEALAACARIAAELGYDEVNINVGCPSDRVQSGNFGVCLMKDPARVRDCVVAMREAV- 142 Query: 143 NKFSISVKIRL 153 + ++VK R+ Sbjct: 143 -ELPVTVKHRI 152 >UniRef50_A5KKR3 Cluster: Putative uncharacterized protein; n=1; Ruminococcus torques ATCC 27756|Rep: Putative uncharacterized protein - Ruminococcus torques ATCC 27756 Length = 211 Score = 39.1 bits (87), Expect = 0.085 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 5/78 (6%) Query: 78 IAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136 + Q N +DFV +K + Y ++LN GCP K + G G L+ PE + D+ Sbjct: 62 VPQILTNCAEDFVQTAKKLEQYGYKEINLNVGCPSKTVVTKGRGAGFLAFPERL-DLF-- 118 Query: 137 LRNVLPN-KFSISVKIRL 153 L V N ISVK R+ Sbjct: 119 LEEVFQNCPIDISVKTRI 136 >UniRef50_Q4Q669 Cluster: Dihydrouridine synthase (Dus), putative; n=3; Leishmania|Rep: Dihydrouridine synthase (Dus), putative - Leishmania major Length = 661 Score = 39.1 bits (87), Expect = 0.085 Identities = 22/55 (40%), Positives = 32/55 (58%), Gaps = 2/55 (3%) Query: 101 DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLN 155 D VD+N GCPQ A + YG L+ E+I+ IV L L + ++VKIR+ + Sbjct: 282 DAVDVNLGCPQGIARRGHYGSFLMEDWELIHTIVHTLHVEL--EVPVTVKIRVFD 334 Score = 35.5 bits (78), Expect = 1.1 Identities = 16/41 (39%), Positives = 25/41 (60%) Query: 26 PMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARAN 66 PMV S++ FR L R + A + +TPM+ A SF + R++ Sbjct: 119 PMVDQSELPFRMLCRQYGATVAYTPMLHAKSFADGAVYRSH 159 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.323 0.136 0.412 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 234,893,814 Number of Sequences: 1657284 Number of extensions: 8958832 Number of successful extensions: 18308 Number of sequences better than 10.0: 294 Number of HSP's better than 10.0 without gapping: 189 Number of HSP's successfully gapped in prelim test: 105 Number of HSP's that attempted gapping in prelim test: 17835 Number of HSP's gapped (non-prelim): 340 length of query: 222 length of database: 575,637,011 effective HSP length: 98 effective length of query: 124 effective length of database: 413,223,179 effective search space: 51239674196 effective search space used: 51239674196 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (22.0 bits) S2: 70 (32.3 bits)
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