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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000375-TA|BGIBMGA000375-PA|IPR001269|Dihydrouridine
synthase, DuS
         (222 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000D5693C Cluster: PREDICTED: similar to dihydrouri...   258   1e-67
UniRef50_Q0IFC6 Cluster: tRNA-dihydrouridine synthase; n=2; Culi...   249   5e-65
UniRef50_UPI00015B403F Cluster: PREDICTED: similar to MGC79829 p...   245   8e-64
UniRef50_O95620 Cluster: tRNA-dihydrouridine synthase 4-like; n=...   216   4e-55
UniRef50_Q9VJ06 Cluster: CG10495-PA; n=2; Sophophora|Rep: CG1049...   214   2e-54
UniRef50_Q54ES7 Cluster: Putative uncharacterized protein; n=1; ...   177   2e-43
UniRef50_Q09504 Cluster: Uncharacterized tRNA-dihydrouridine syn...   174   1e-42
UniRef50_O74553 Cluster: tRNA dihydrouridine synthase Dus4; n=1;...   170   3e-41
UniRef50_A7EMF2 Cluster: Putative uncharacterized protein; n=1; ...   154   2e-36
UniRef50_Q5A4Y0 Cluster: Potential tRNA dihydrouridine synthase;...   153   3e-36
UniRef50_Q06063 Cluster: tRNA-dihydrouridine synthase 4; n=10; S...   146   4e-34
UniRef50_Q583Y8 Cluster: TRNA-dihydrouridine synthase 4, putativ...   145   9e-34
UniRef50_Q4Q391 Cluster: Putative uncharacterized protein; n=3; ...   134   1e-30
UniRef50_A5K1E0 Cluster: tRNA-dihydrouridine synthase, putative;...   128   8e-29
UniRef50_Q54XQ6 Cluster: Putative uncharacterized protein; n=1; ...   127   2e-28
UniRef50_Q9FH91 Cluster: Gb|AAF51525.1; n=6; Magnoliophyta|Rep: ...   123   3e-27
UniRef50_Q9VPM1 Cluster: CG3645-PA, isoform A; n=2; Diptera|Rep:...   123   3e-27
UniRef50_A7AQM0 Cluster: Dihydrouridine synthase, putative; n=1;...   122   5e-27
UniRef50_Q9XVN8 Cluster: Putative uncharacterized protein; n=2; ...   122   9e-27
UniRef50_Q5KPM6 Cluster: Putative uncharacterized protein; n=2; ...   121   1e-26
UniRef50_A4S141 Cluster: Predicted protein; n=1; Ostreococcus lu...   121   2e-26
UniRef50_Q5CSA9 Cluster: Dus1p, tRNA dihydrouridine synthase; n=...   117   2e-25
UniRef50_Q6P1R4 Cluster: tRNA-dihydrouridine synthase 1-like; n=...   115   8e-25
UniRef50_A0EG06 Cluster: Chromosome undetermined scaffold_94, wh...   112   8e-24
UniRef50_A2FU21 Cluster: Putative uncharacterized protein; n=1; ...   110   2e-23
UniRef50_UPI000023CFE7 Cluster: hypothetical protein FG01258.1; ...   105   9e-22
UniRef50_Q4UGK9 Cluster: Putative uncharacterized protein; n=2; ...   104   2e-21
UniRef50_P53759 Cluster: tRNA-dihydrouridine synthase 1; n=11; S...   103   4e-21
UniRef50_UPI0000499E32 Cluster: conserved hypothetical protein; ...   101   1e-20
UniRef50_Q9HGN6 Cluster: tRNA dihydrouridine synthase Dus1; n=1;...   100   3e-20
UniRef50_A2EF32 Cluster: Dihydrouridine synthase, putative; n=1;...    99   8e-20
UniRef50_Q8SUV4 Cluster: Putative uncharacterized protein ECU07_...    99   8e-20
UniRef50_Q8PX79 Cluster: NifR3-like protein; n=5; Archaea|Rep: N...    98   1e-19
UniRef50_A2DHB4 Cluster: Putative uncharacterized protein; n=1; ...    97   2e-19
UniRef50_Q00RI1 Cluster: OSIGBa0125M19.5 protein; n=9; Magnoliop...    96   7e-19
UniRef50_A6DCX2 Cluster: tRNA-dihydrouridine synthase B; n=1; Ca...    95   9e-19
UniRef50_A4RU69 Cluster: Predicted protein; n=2; Ostreococcus|Re...    95   9e-19
UniRef50_Q4PBU9 Cluster: Putative uncharacterized protein; n=1; ...    95   1e-18
UniRef50_Q57V78 Cluster: TRNA-dihydrouridine synthase 1, putativ...    91   2e-17
UniRef50_UPI000023EA9A Cluster: hypothetical protein FG07217.1; ...    90   5e-17
UniRef50_A6RW05 Cluster: Putative uncharacterized protein; n=1; ...    89   8e-17
UniRef50_Q6F288 Cluster: TRNA dihydrouridine synthetase; n=3; Mo...    89   1e-16
UniRef50_A2EN54 Cluster: Putative uncharacterized protein; n=1; ...    89   1e-16
UniRef50_Q4PG83 Cluster: Putative uncharacterized protein; n=1; ...    88   2e-16
UniRef50_A2F0D1 Cluster: Putative uncharacterized protein; n=1; ...    85   1e-15
UniRef50_A4M5I1 Cluster: Dihydrouridine synthase, DuS; n=1; Petr...    84   2e-15
UniRef50_Q5KP54 Cluster: TRNA dihydrouridine synthase, putative;...    84   2e-15
UniRef50_Q9XWJ9 Cluster: Putative uncharacterized protein; n=2; ...    83   7e-15
UniRef50_A2ACC0 Cluster: Novel protein; n=17; Eumetazoa|Rep: Nov...    82   9e-15
UniRef50_Q4D174 Cluster: Dihydrouridine synthase (Dus), putative...    82   1e-14
UniRef50_Q7SGX4 Cluster: Putative uncharacterized protein NCU031...    81   2e-14
UniRef50_Q6AJZ5 Cluster: TRNA-dihydrouridine synthase; n=1; Desu...    80   4e-14
UniRef50_Q4WRF0 Cluster: Dihydrouridine synthase family protein,...    79   7e-14
UniRef50_Q9NX74 Cluster: tRNA-dihydrouridine synthase 2-like; n=...    79   9e-14
UniRef50_A2FJB5 Cluster: TIM-barrel protein, nifR3 family protei...    79   1e-13
UniRef50_Q54QJ2 Cluster: Putative uncharacterized protein; n=1; ...    78   2e-13
UniRef50_Q5KGP0 Cluster: Putative uncharacterized protein; n=3; ...    78   2e-13
UniRef50_UPI00015B40A4 Cluster: PREDICTED: similar to tRNA-dihyd...    77   3e-13
UniRef50_Q7RX85 Cluster: Putative uncharacterized protein NCU000...    77   3e-13
UniRef50_Q59YG4 Cluster: Potential tRNA dihydrouridine synthase;...    76   6e-13
UniRef50_Q1NXZ7 Cluster: Dihydrouridine synthase TIM-barrel prot...    75   1e-12
UniRef50_Q8RFK3 Cluster: Nitrogen regulation protein NIFR3; n=3;...    75   2e-12
UniRef50_Q2H6D9 Cluster: Putative uncharacterized protein; n=1; ...    75   2e-12
UniRef50_Q8KB61 Cluster: TIM-barrel protein, nifR3 family; n=10;...    74   3e-12
UniRef50_Q9VY45 Cluster: CG1434-PA; n=6; Endopterygota|Rep: CG14...    73   4e-12
UniRef50_Q4S086 Cluster: Chromosome undetermined SCAF14784, whol...    73   6e-12
UniRef50_Q6C002 Cluster: Yarrowia lipolytica chromosome F of str...    73   7e-12
UniRef50_O74731 Cluster: tRNA dihydrouridine synthase Dus2; n=1;...    73   7e-12
UniRef50_A4RL93 Cluster: Putative uncharacterized protein; n=1; ...    73   7e-12
UniRef50_A6DPY9 Cluster: Putative uncharacterized protein; n=1; ...    72   1e-11
UniRef50_Q74EF7 Cluster: Dihydrouridine synthase family protein;...    72   1e-11
UniRef50_Q31II6 Cluster: Dihydrouridine synthase; n=1; Thiomicro...    71   2e-11
UniRef50_A4XH30 Cluster: Putative TIM-barrel protein, nifR3 fami...    71   2e-11
UniRef50_A5DYF6 Cluster: Putative uncharacterized protein; n=1; ...    71   2e-11
UniRef50_A1SX05 Cluster: Dihydrouridine synthase, DuS; n=3; Alte...    71   2e-11
UniRef50_Q550J6 Cluster: Putative uncharacterized protein; n=2; ...    71   2e-11
UniRef50_Q4PIC3 Cluster: Putative uncharacterized protein; n=1; ...    71   2e-11
UniRef50_Q7MXX6 Cluster: TIM-barrel protein, putative, NifR3 fam...    71   3e-11
UniRef50_Q6BX60 Cluster: Debaryomyces hansenii chromosome B of s...    71   3e-11
UniRef50_O67533 Cluster: Probable tRNA-dihydrouridine synthase; ...    71   3e-11
UniRef50_Q899H0 Cluster: Nitrogen regulation protein nifR3; n=24...    70   4e-11
UniRef50_Q47C15 Cluster: Dihydrouridine synthase, DuS; n=2; Beta...    70   4e-11
UniRef50_Q1IVR5 Cluster: Dihydrouridine synthase TIM-barrel prot...    70   5e-11
UniRef50_A6BZR9 Cluster: Predicted TIM-barrel enzyme, possibly d...    70   5e-11
UniRef50_A6CBK4 Cluster: Predicted TIM-barrel enzyme, possibly d...    69   7e-11
UniRef50_Q6SFW7 Cluster: NifR3/Smm1 family protein; n=1; uncultu...    69   9e-11
UniRef50_Q0YFW9 Cluster: Dihydrouridine synthase TIM-barrel prot...    69   9e-11
UniRef50_A2DYY3 Cluster: Putative uncharacterized protein; n=1; ...    69   1e-10
UniRef50_Q5ZRM0 Cluster: Nitrogen regulation protein; n=4; Legio...    68   2e-10
UniRef50_Q0FAI7 Cluster: tRNA-dihydrouridine synthase, putative;...    68   2e-10
UniRef50_Q14SX5 Cluster: Putative dihydrouridine synthase; n=1; ...    67   3e-10
UniRef50_Q5M689 Cluster: Possible transcriptional regulator; n=2...    66   5e-10
UniRef50_A0LJ96 Cluster: Putative TIM-barrel protein, nifR3 fami...    66   5e-10
UniRef50_Q64MI4 Cluster: Putative TIM-barrel enzyme; n=3; Bacter...    66   7e-10
UniRef50_Q6MNE4 Cluster: Dihydrouridine synthase family protein;...    66   9e-10
UniRef50_Q0B0N8 Cluster: Putative TIM-barrel protein, NifR3 fami...    66   9e-10
UniRef50_Q9JUP6 Cluster: tRNA-dihydrouridine synthase C; n=4; Ne...    66   9e-10
UniRef50_Q8ZAX7 Cluster: tRNA-dihydrouridine synthase B; n=214; ...    66   9e-10
UniRef50_P37567 Cluster: Probable tRNA-dihydrouridine synthase 1...    66   9e-10
UniRef50_A6LGT0 Cluster: Putative TIM-barrel enzyme; n=1; Paraba...    65   1e-09
UniRef50_Q7R3H4 Cluster: GLP_158_49916_51304; n=1; Giardia lambl...    65   1e-09
UniRef50_A2QES0 Cluster: Contig An02c0390, complete genome; n=12...    65   1e-09
UniRef50_Q6MNE9 Cluster: Nitrogen regulation protein nifR3; n=1;...    65   2e-09
UniRef50_Q6AKJ6 Cluster: Putative uncharacterized protein; n=1; ...    65   2e-09
UniRef50_Q1Q3Q8 Cluster: Strongly similar to tRNA-dihydrouridine...    64   3e-09
UniRef50_Q1DPY5 Cluster: Putative uncharacterized protein; n=1; ...    64   3e-09
UniRef50_Q7VKU5 Cluster: tRNA-dihydrouridine synthase C; n=118; ...    64   3e-09
UniRef50_Q607L4 Cluster: TIM-barrel protein, yjbN family; n=10; ...    64   3e-09
UniRef50_Q0G7A4 Cluster: Nitrogen regulation protein nifr3; n=2;...    64   3e-09
UniRef50_Q127F8 Cluster: Dihydrouridine synthase, DuS; n=3; Prot...    63   6e-09
UniRef50_Q7R1J1 Cluster: GLP_38_15456_16676; n=1; Giardia lambli...    63   6e-09
UniRef50_Q9CLW3 Cluster: tRNA-dihydrouridine synthase B; n=17; P...    63   6e-09
UniRef50_P53720 Cluster: tRNA-dihydrouridine synthase 2; n=7; Sa...    63   6e-09
UniRef50_Q8XYX1 Cluster: tRNA-dihydrouridine synthase C; n=26; P...    62   8e-09
UniRef50_O52532 Cluster: tRNA-dihydrouridine synthase B; n=6; Ga...    62   8e-09
UniRef50_A3RPJ2 Cluster: TRNA-dihydrouridine synthase; n=2; Prot...    62   1e-08
UniRef50_Q4PAE4 Cluster: Putative uncharacterized protein; n=1; ...    62   1e-08
UniRef50_A7EHJ6 Cluster: Putative uncharacterized protein; n=2; ...    62   1e-08
UniRef50_A6R3V4 Cluster: Putative uncharacterized protein; n=1; ...    62   1e-08
UniRef50_Q08111 Cluster: Probable tRNA-dihydrouridine synthase; ...    62   1e-08
UniRef50_Q3AZ67 Cluster: Dihydrouridine synthase TIM-barrel prot...    61   2e-08
UniRef50_Q2RM54 Cluster: Dihydrouridine synthase TIM-barrel prot...    61   2e-08
UniRef50_Q22A31 Cluster: TIM-barrel protein, yjbN family; n=1; T...    61   2e-08
UniRef50_O25427 Cluster: Probable tRNA-dihydrouridine synthase; ...    61   2e-08
UniRef50_Q8YAB9 Cluster: Lmo0227 protein; n=55; Bacteria|Rep: Lm...    61   2e-08
UniRef50_Q7XWZ9 Cluster: OSJNBa0079F16.4 protein; n=8; Oryza sat...    61   2e-08
UniRef50_Q6PEH0 Cluster: Zgc:63779; n=8; Chordata|Rep: Zgc:63779...    60   3e-08
UniRef50_A4SY29 Cluster: Dihydrouridine synthase, DuS; n=1; Poly...    59   7e-08
UniRef50_A6U9Y2 Cluster: Dihydrouridine synthase DuS; n=2; Sinor...    59   1e-07
UniRef50_A4S604 Cluster: Predicted protein; n=1; Ostreococcus lu...    59   1e-07
UniRef50_Q54CU9 Cluster: Putative uncharacterized protein; n=1; ...    59   1e-07
UniRef50_A7CWF1 Cluster: Putative TIM-barrel protein, nifR3 fami...    58   1e-07
UniRef50_Q9TYN2 Cluster: Putative uncharacterized protein Y37E11...    58   1e-07
UniRef50_Q9ZED2 Cluster: Probable tRNA-dihydrouridine synthase; ...    58   1e-07
UniRef50_Q9RRP8 Cluster: NifR3 protein; n=2; Deinococcus|Rep: Ni...    58   2e-07
UniRef50_Q3IKP0 Cluster: TRNA-dihydrouridine synthase C; n=5; Al...    58   2e-07
UniRef50_A1VHK2 Cluster: Dihydrouridine synthase, DuS; n=4; Desu...    58   2e-07
UniRef50_Q5SMC7 Cluster: TRNA-dihydrouridine synthase; n=2; Ther...    58   2e-07
UniRef50_Q5LQV9 Cluster: TRNA-dihydrouridine synthase A; n=46; B...    58   2e-07
UniRef50_Q4FQ57 Cluster: Possible tRNA-dihydrouridine synthase; ...    58   2e-07
UniRef50_Q1QZQ6 Cluster: Dihydrouridine synthase, DuS; n=1; Chro...    58   2e-07
UniRef50_A6W1E8 Cluster: Dihydrouridine synthase DuS; n=1; Marin...    58   2e-07
UniRef50_Q96G46 Cluster: tRNA-dihydrouridine synthase 3-like; n=...    58   2e-07
UniRef50_Q8GQD1 Cluster: NifR; n=5; Leptospira|Rep: NifR - Lepto...    57   3e-07
UniRef50_A3JG66 Cluster: Putative uncharacterized protein; n=3; ...    57   3e-07
UniRef50_A5D5Q0 Cluster: TRNA-dihydrouridine synthase; n=5; Firm...    57   4e-07
UniRef50_Q9LY64 Cluster: Putative uncharacterized protein MAA21_...    57   4e-07
UniRef50_Q9Z7D8 Cluster: Predicted oxidoreductase; n=7; Chlamydi...    56   7e-07
UniRef50_Q5LRN6 Cluster: TRNA-dihydrouridine synthase, putative;...    56   7e-07
UniRef50_Q4QEF9 Cluster: Putative uncharacterized protein; n=3; ...    56   7e-07
UniRef50_A4EC62 Cluster: Putative uncharacterized protein; n=1; ...    56   9e-07
UniRef50_Q251N6 Cluster: Putative uncharacterized protein; n=2; ...    55   1e-06
UniRef50_Q55724 Cluster: Probable tRNA-dihydrouridine synthase 1...    55   1e-06
UniRef50_Q1VN28 Cluster: Dihydrouridine synthase TIM-barrel prot...    55   2e-06
UniRef50_Q7R9R0 Cluster: Uncharacterized protein family UPF0034,...    55   2e-06
UniRef50_Q7R684 Cluster: GLP_574_116690_118078; n=1; Giardia lam...    54   2e-06
UniRef50_Q21L63 Cluster: Dihydrouridine synthase, DuS; n=1; Sacc...    54   3e-06
UniRef50_A7DPL5 Cluster: Putative TIM-barrel protein, nifR3 fami...    54   3e-06
UniRef50_UPI00015B6197 Cluster: PREDICTED: similar to CG10463-PA...    54   4e-06
UniRef50_Q0VPD7 Cluster: TIM-barrel protein, yjbN family; n=4; B...    54   4e-06
UniRef50_Q91XI1 Cluster: tRNA-dihydrouridine synthase 3-like; n=...    54   4e-06
UniRef50_A4RQU5 Cluster: Predicted protein; n=2; Ostreococcus|Re...    53   5e-06
UniRef50_Q8YMN5 Cluster: Transcriptional regulator; n=5; Bacteri...    53   6e-06
UniRef50_Q6MAU6 Cluster: Putative uncharacterized protein yohI; ...    53   6e-06
UniRef50_Q4FLD8 Cluster: Putative uncharacterized protein; n=2; ...    53   6e-06
UniRef50_Q30WR3 Cluster: Dihydrouridine synthase family protein;...    53   6e-06
UniRef50_A6NW05 Cluster: Putative uncharacterized protein; n=1; ...    53   6e-06
UniRef50_A6GHV6 Cluster: Dihydrouridine synthase family protein;...    53   6e-06
UniRef50_Q5CRK5 Cluster: Ylr401cp-like protein with 2 CCCH domai...    53   6e-06
UniRef50_A7S213 Cluster: Predicted protein; n=1; Nematostella ve...    53   6e-06
UniRef50_O83945 Cluster: Probable tRNA-dihydrouridine synthase; ...    53   6e-06
UniRef50_Q6MRF1 Cluster: Transcription regulator homolog yacF; n...    52   9e-06
UniRef50_Q3E0H8 Cluster: Dihydrouridine synthase TIM-barrel prot...    52   9e-06
UniRef50_Q884C6 Cluster: tRNA-dihydrouridine synthase C; n=8; Pr...    52   9e-06
UniRef50_Q489F6 Cluster: NifR3/Smm1 family protein; n=2; Proteob...    52   1e-05
UniRef50_Q1N033 Cluster: Putative uncharacterized protein; n=1; ...    52   1e-05
UniRef50_Q056Y8 Cluster: TRNA-dihydrouridine synthase A; n=1; Bu...    52   1e-05
UniRef50_A1RNI1 Cluster: TIM-barrel protein, yjbN family; n=30; ...    52   1e-05
UniRef50_A3LUK5 Cluster: Dihydrouridine synthase of tRNA; n=6; S...    52   1e-05
UniRef50_UPI0000499494 Cluster: conserved hypothetical protein; ...    51   2e-05
UniRef50_Q012U0 Cluster: Nitrogen regulation family protein; n=2...    51   2e-05
UniRef50_A7HK00 Cluster: Dihydrouridine synthase DuS; n=4; Therm...    51   3e-05
UniRef50_A4BCJ5 Cluster: NifR3/Smm1 family protein; n=2; Gammapr...    51   3e-05
UniRef50_A4AAB0 Cluster: TRNA-dihydrouridine synthase C; n=2; un...    51   3e-05
UniRef50_UPI0000E472BC Cluster: PREDICTED: similar to tRNA-dihyd...    50   3e-05
UniRef50_Q2UL89 Cluster: Uncharacterized conserved protein; n=15...    50   3e-05
UniRef50_A6DU09 Cluster: Dihydrouridine synthase family protein;...    50   5e-05
UniRef50_Q89LQ7 Cluster: Nitrogen regulation protein; n=22; Alph...    50   6e-05
UniRef50_O51243 Cluster: Putative uncharacterized protein BB0225...    50   6e-05
UniRef50_Q1JWD3 Cluster: Dihydrouridine synthase, DuS; n=1; Desu...    50   6e-05
UniRef50_Q9V0Y6 Cluster: Dihydroorotate dehydrogenase; n=8; Eury...    50   6e-05
UniRef50_Q7UXK8 Cluster: Putative uncharacterized protein; n=3; ...    49   8e-05
UniRef50_Q6M9N8 Cluster: Putative uncharacterized protein; n=1; ...    49   8e-05
UniRef50_A6EDJ3 Cluster: Probable TIM-barrel protein, NifR3 fami...    49   8e-05
UniRef50_Q9FI41 Cluster: Emb|CAB87804.1; n=7; Magnoliophyta|Rep:...    49   8e-05
UniRef50_Q0F181 Cluster: Dihydrouridine synthase TIM-barrel prot...    49   1e-04
UniRef50_Q04VP3 Cluster: TRNA-dihydrouridine synthase; n=4; Lept...    49   1e-04
UniRef50_A5EVV4 Cluster: Dihydrouridine synthase; n=1; Dicheloba...    49   1e-04
UniRef50_A4TZK1 Cluster: Dihydrouridine synthase, DuS; n=4; Prot...    49   1e-04
UniRef50_A1AW94 Cluster: TIM-barrel protein, yjbN family; n=1; C...    49   1e-04
UniRef50_Q5HJT5 Cluster: Probable tRNA-dihydrouridine synthase; ...    49   1e-04
UniRef50_A1IF01 Cluster: Dihydrouridine synthase family protein;...    48   1e-04
UniRef50_Q7X346 Cluster: Putative uncharacterized protein; n=1; ...    48   2e-04
UniRef50_UPI0000DAE45A Cluster: hypothetical protein Rgryl_01000...    48   2e-04
UniRef50_Q2RZL4 Cluster: NifR3 family enzyme; n=1; Salinibacter ...    48   2e-04
UniRef50_Q7UBC5 Cluster: tRNA-dihydrouridine synthase A; n=231; ...    48   2e-04
UniRef50_Q2NEG1 Cluster: PyrD; n=1; Methanosphaera stadtmanae DS...    47   3e-04
UniRef50_Q2IG49 Cluster: Dihydrouridine synthase TIM-barrel prot...    47   4e-04
UniRef50_Q4Q231 Cluster: Dihydrouridine synthase domain protein-...    47   4e-04
UniRef50_A1AT39 Cluster: Dihydrouridine synthase, DuS; n=7; Desu...    46   6e-04
UniRef50_Q06053 Cluster: tRNA-dihydrouridine synthase 3; n=6; Sa...    46   7e-04
UniRef50_Q5ZVH8 Cluster: Zinc binding TIM barrel protein, YjbN f...    46   0.001
UniRef50_Q8SUY1 Cluster: Putative uncharacterized protein ECU07_...    46   0.001
UniRef50_Q6AJ40 Cluster: Putative uncharacterized protein; n=1; ...    45   0.002
UniRef50_A5GPV9 Cluster: TRNA-dihydrouridine synthase A; n=21; C...    45   0.002
UniRef50_A0EAZ6 Cluster: Chromosome undetermined scaffold_87, wh...    45   0.002
UniRef50_O31546 Cluster: Probable tRNA-dihydrouridine synthase 2...    45   0.002
UniRef50_UPI000058804E Cluster: PREDICTED: similar to MGC53781 p...    44   0.002
UniRef50_Q2RTR9 Cluster: Dihydrouridine synthase TIM-barrel prot...    44   0.002
UniRef50_A4RVX6 Cluster: Predicted protein; n=2; Ostreococcus|Re...    44   0.002
UniRef50_Q9VIS4 Cluster: CG10463-PA; n=3; Sophophora|Rep: CG1046...    44   0.002
UniRef50_Q7UKE8 Cluster: Putative uncharacterized protein; n=2; ...    44   0.003
UniRef50_A1IED4 Cluster: Putative uncharacterized protein; n=1; ...    44   0.003
UniRef50_Q01ML2 Cluster: H0613H07.1 protein; n=10; Eukaryota|Rep...    44   0.004
UniRef50_Q5FTP7 Cluster: Nitrogen assimilation regulatory protei...    43   0.005
UniRef50_A6PPM6 Cluster: Dihydrouridine synthase, DuS; n=1; Vict...    43   0.005
UniRef50_A5N517 Cluster: Predicted NADH oxidase; n=1; Clostridiu...    43   0.005
UniRef50_Q2HDP2 Cluster: Putative uncharacterized protein; n=1; ...    43   0.005
UniRef50_A0Z3E6 Cluster: Dihydroorotate dehydrogenase/oxidoreduc...    43   0.007
UniRef50_Q582L4 Cluster: TRNA-dihydrouridine synthase 3, putativ...    43   0.007
UniRef50_Q8A2H9 Cluster: Putative nifR3 family TIM-barrel enzyme...    42   0.009
UniRef50_Q83D40 Cluster: TIM-barrel protein, yjbN family; n=7; B...    42   0.012
UniRef50_A5FPW7 Cluster: Dihydroorotate dehydrogenase family pro...    42   0.012
UniRef50_Q9UTH9 Cluster: tRNA dihydrouridine synthase Dus3; n=1;...    42   0.012
UniRef50_A7DKP5 Cluster: Dihydrouridine synthase, DuS; n=2; Meth...    42   0.016
UniRef50_A4BWB1 Cluster: Putative uncharacterized protein; n=5; ...    41   0.021
UniRef50_A7AWB5 Cluster: Dihydrouridine synthase (Dus) domain co...    41   0.021
UniRef50_Q9PGB5 Cluster: tRNA-dihydrouridine synthase A; n=8; Pr...    41   0.021
UniRef50_Q979G6 Cluster: Dihydroorotate dehydrogenase; n=4; Ther...    41   0.028
UniRef50_Q38BB4 Cluster: TRNA-dihydrouridine synthase 2, putativ...    40   0.037
UniRef50_Q8G7W8 Cluster: Possible NifR3-like protein; n=4; Bifid...    40   0.049
UniRef50_Q0C0N1 Cluster: Putative tRNA-dihydrouridine synthase; ...    40   0.049
UniRef50_Q6C4K3 Cluster: Similar to DEHA0D12364g Debaryomyces ha...    40   0.049
UniRef50_Q7PVV7 Cluster: ENSANGP00000016833; n=2; Endopterygota|...    40   0.065
UniRef50_Q9K9W1 Cluster: Dihydroorotate dehydrogenase; n=1; Baci...    40   0.065
UniRef50_Q73P17 Cluster: Dihydroorotate dehydrogenase/oxidoreduc...    39   0.085
UniRef50_Q090Q9 Cluster: TRNA-dihydrouridine synthase B; n=2; Cy...    39   0.085
UniRef50_A6GGZ7 Cluster: Putative uncharacterized protein; n=2; ...    39   0.085
UniRef50_A5KKR3 Cluster: Putative uncharacterized protein; n=1; ...    39   0.085
UniRef50_Q4Q669 Cluster: Dihydrouridine synthase (Dus), putative...    39   0.085
UniRef50_Q8TXU6 Cluster: Dihydroorotate dehydrogenase; n=1; Meth...    39   0.085
UniRef50_Q73RG6 Cluster: Dihydrouridine synthase, putative; n=1;...    39   0.11 
UniRef50_A5WG83 Cluster: TIM-barrel protein, yjbN family; n=4; M...    39   0.11 
UniRef50_O53835 Cluster: Probable tRNA-dihydrouridine synthase; ...    39   0.11 
UniRef50_A5EXU5 Cluster: TRNA-dihydrouridine synthase A; n=1; Di...    38   0.15 
UniRef50_A1X3A1 Cluster: Putative NADH:flavin oxidoreductase; n=...    38   0.15 
UniRef50_Q17M24 Cluster: tRNA-dihydrouridine synthase; n=1; Aede...    38   0.15 
UniRef50_A7IA09 Cluster: Thiamine-phosphate pyrophosphorylase; n...    38   0.15 
UniRef50_Q97DM0 Cluster: Predicted TIM-barrel enzyme, nifR3 fami...    38   0.20 
UniRef50_O51679 Cluster: Histidine phosphokinase/phophatase, put...    38   0.20 
UniRef50_Q9RDC6 Cluster: Putative uncharacterized protein SCO249...    38   0.26 
UniRef50_Q1EYG5 Cluster: NADH:flavin oxidoreductase/NADH oxidase...    38   0.26 
UniRef50_A4S3Q5 Cluster: Predicted protein; n=2; Eukaryota|Rep: ...    37   0.34 
UniRef50_Q8PW56 Cluster: Dihydroorotate dehydrogenase; n=14; Eur...    37   0.46 
UniRef50_A2DZN8 Cluster: Oxidoreductase, FAD/FMN-binding family ...    36   0.60 
UniRef50_Q5KC68 Cluster: TRNA dihydrouridine synthase, putative;...    36   0.60 
UniRef50_Q9A7I4 Cluster: Nitrogen regulation protein Nifr3; n=2;...    36   0.80 
UniRef50_Q97K75 Cluster: NADH:flavin oxidoreductase, possible NA...    36   0.80 
UniRef50_A4YUQ6 Cluster: Putative tRNA-dihydrouridine synthase; ...    36   0.80 
UniRef50_A4EV41 Cluster: Oxidoreductase, FAD/FMN-binding protein...    36   0.80 
UniRef50_Q24833 Cluster: Putative nitrogen fixation regulatory p...    36   0.80 
UniRef50_Q1G992 Cluster: Dihydroorotate dehydrogenase; n=3; Lact...    36   1.1  
UniRef50_Q8ESS1 Cluster: 1-(5-phosphoribosyl)-5-[(5-phosphoribos...    36   1.1  
UniRef50_Q4AHG7 Cluster: Dihydrouridine synthase, DuS; n=1; Chlo...    35   1.4  
UniRef50_A7BE39 Cluster: Putative uncharacterized protein; n=1; ...    35   1.4  
UniRef50_Q0AWX0 Cluster: NADH:flavin oxidoreductase, Old Yellow ...    35   1.8  
UniRef50_Q010A0 Cluster: tRNA-dihydrouridine synthase; n=1; Ostr...    35   1.8  
UniRef50_A6P2M8 Cluster: Putative uncharacterized protein; n=1; ...    34   2.4  
UniRef50_A3VNG3 Cluster: Dihydrouridine synthase TIM-barrel prot...    34   2.4  
UniRef50_A2DV72 Cluster: 4Fe-4S binding domain containing protei...    34   2.4  
UniRef50_A0LHK5 Cluster: 1-(5-phosphoribosyl)-5-[(5-phosphoribos...    34   2.4  
UniRef50_Q65PP9 Cluster: Lj928 prophage protein; n=24; root|Rep:...    34   3.2  
UniRef50_Q09E70 Cluster: Thiazole biosynthesis protein ThiG; n=1...    34   3.2  
UniRef50_A7AAN4 Cluster: Putative uncharacterized protein; n=2; ...    33   4.2  
UniRef50_A0DW78 Cluster: Chromosome undetermined scaffold_662, w...    33   4.2  
UniRef50_A6VYA3 Cluster: TIM-barrel protein, yjbN family; n=8; P...    33   5.6  
UniRef50_Q8RI59 Cluster: Thiamine-phosphate pyrophosphorylase; n...    33   5.6  
UniRef50_O29513 Cluster: Dihydroorotate dehydrogenase; n=1; Arch...    33   5.6  
UniRef50_Q193G0 Cluster: DnaQ family exonuclease/DinG family hel...    32   9.8  
UniRef50_A1BEJ0 Cluster: NADH:flavin oxidoreductase/NADH oxidase...    32   9.8  
UniRef50_Q013U5 Cluster: CG3645-PB, isoform B; n=1; Ostreococcus...    32   9.8  
UniRef50_A2DPI6 Cluster: Putative uncharacterized protein; n=1; ...    32   9.8  
UniRef50_Q0CTZ8 Cluster: Putative uncharacterized protein; n=2; ...    32   9.8  
UniRef50_Q466J2 Cluster: NADH-dependent flavine oxidoreductase; ...    32   9.8  

>UniRef50_UPI0000D5693C Cluster: PREDICTED: similar to
           dihydrouridine synthase 4-like; n=3; Coelomata|Rep:
           PREDICTED: similar to dihydrouridine synthase 4-like -
           Tribolium castaneum
          Length = 451

 Score =  258 bits (631), Expect = 1e-67
 Identities = 119/216 (55%), Positives = 158/216 (73%), Gaps = 4/216 (1%)

Query: 1   MKEICDIMEKFADAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQN 60
           +K   D+M+ FAD KI    +K+CAPMVRYSK+ FR LV+++N DLC+TPMILADSFC++
Sbjct: 9   LKHSTDVMQLFADKKI----VKICAPMVRYSKLQFRNLVKSYNCDLCYTPMILADSFCKS 64

Query: 61  SKARANEFMTTTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYG 120
            KARANEF T   D P+I QFAAN   DFV A+ +V P+ DGVDLNCGCPQ+WA   G G
Sbjct: 65  GKARANEFTTNMNDTPLITQFAANKVYDFVGAAYMVSPFCDGVDLNCGCPQRWAKLQGLG 124

Query: 121 CSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEE 180
           C +L KPE+IYD+VK  RNV+P  F++SVK+RL  D++++V +C+QLE CGV+FLT    
Sbjct: 125 CIMLEKPEVIYDLVKQCRNVIPKPFTVSVKLRLQKDLRRSVEICRQLEHCGVSFLTVHGR 184

Query: 181 HCTKSSGPVDINGLKEVREALSVPMVANGGVKHLND 216
              + +G V+   L  +  +++VP+VANGGVK L D
Sbjct: 185 TPDQLTGEVNKEALNLIVGSVNVPVVANGGVKSLED 220


>UniRef50_Q0IFC6 Cluster: tRNA-dihydrouridine synthase; n=2;
           Culicidae|Rep: tRNA-dihydrouridine synthase - Aedes
           aegypti (Yellowfever mosquito)
          Length = 391

 Score =  249 bits (609), Expect = 5e-65
 Identities = 114/209 (54%), Positives = 153/209 (73%), Gaps = 2/209 (0%)

Query: 11  FADAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMT 70
           F +A+   +YLK+CAPMVRYSK+ FR LVR++  DL FT MI+ADSFCQ+ KAR NEF T
Sbjct: 14  FREARAKDSYLKICAPMVRYSKLEFRNLVRSYGTDLTFTSMIMADSFCQSEKARLNEFTT 73

Query: 71  TTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEII 130
              D PVIAQFAA N  DF+ A+++ +PYVDGVDLNCGCPQ+WAM+DGYG +LL  PE+I
Sbjct: 74  NRDDTPVIAQFAAKNAVDFLSATEMTFPYVDGVDLNCGCPQRWAMQDGYGSALLRTPELI 133

Query: 131 YDIVKGLRNVLPNKFSISVKIRLL-NDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGP 188
            D++  +R  LP+ FS+SVK+RLL   +  T+ +C+QLE CG+TF+T        K++ P
Sbjct: 134 ADMLSTVRRNLPSTFSVSVKVRLLQKSLSATIDMCRQLEACGITFITVHGRTPAQKTNIP 193

Query: 189 VDINGLKEVREALSVPMVANGGVKHLNDA 217
           V+   LKE++ +L +P+VANG +  L DA
Sbjct: 194 VNQEALKEIKSSLGIPVVANGDIFSLQDA 222


>UniRef50_UPI00015B403F Cluster: PREDICTED: similar to MGC79829
           protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to MGC79829 protein - Nasonia vitripennis
          Length = 346

 Score =  245 bits (599), Expect = 8e-64
 Identities = 110/198 (55%), Positives = 147/198 (74%)

Query: 22  KVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQF 81
           KVCAPMVRYSK+ FRTLVR ++ D+CFTPMILADSF Q+SKAR +EF T   D P+I QF
Sbjct: 16  KVCAPMVRYSKLPFRTLVRKYDCDICFTPMILADSFVQSSKARDSEFSTNEGDSPLIVQF 75

Query: 82  AANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141
           AA   DDFV+A+++V PY +GVDLNCGCPQ+WA+KDGYG  LL+KP+++ ++V  +RN +
Sbjct: 76  AAKEVDDFVEATEMVAPYSNGVDLNCGCPQRWALKDGYGADLLTKPQLVKELVSNVRNRI 135

Query: 142 PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSGPVDINGLKEVREAL 201
           P  F++SVKIR+L DIKKT+   + +E  GV+FLT         + P+D++ LK VR  +
Sbjct: 136 PKPFTVSVKIRILKDIKKTIEFSRAIEHAGVSFLTVHARTPDMRNEPIDLDSLKLVRSCV 195

Query: 202 SVPMVANGGVKHLNDATT 219
            +PM+ANG V+   DA T
Sbjct: 196 HLPMIANGNVRSFEDAKT 213


>UniRef50_O95620 Cluster: tRNA-dihydrouridine synthase 4-like; n=28;
           Eumetazoa|Rep: tRNA-dihydrouridine synthase 4-like -
           Homo sapiens (Human)
          Length = 317

 Score =  216 bits (527), Expect = 4e-55
 Identities = 96/198 (48%), Positives = 144/198 (72%), Gaps = 1/198 (0%)

Query: 21  LKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQ 80
           +KVCAPMVRYSK+ FRTLVR ++ DLC+TPMI+A  F ++ KAR +EF T   D P+I Q
Sbjct: 28  VKVCAPMVRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSIKARDSEFTTNQGDCPLIVQ 87

Query: 81  FAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140
           FAAN+     DA+++V PY +G+D+NCGCPQ+WAM +GYG  L++KPE++ D+VK +RN 
Sbjct: 88  FAANDARLLSDAARIVCPYANGIDINCGCPQRWAMAEGYGACLINKPELVQDMVKQVRNQ 147

Query: 141 LPNK-FSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSGPVDINGLKEVRE 199
           +    FS+S+KIR+ +D+K+TV LCQ+ E  GV+++T       +   PV  + +K ++E
Sbjct: 148 VETPGFSVSIKIRIHDDLKRTVDLCQKAEATGVSWITVHGRTAEERHQPVHYDSIKIIKE 207

Query: 200 ALSVPMVANGGVKHLNDA 217
            +S+P++ANG ++ L +A
Sbjct: 208 NMSIPVIANGDIRSLKEA 225


>UniRef50_Q9VJ06 Cluster: CG10495-PA; n=2; Sophophora|Rep:
           CG10495-PA - Drosophila melanogaster (Fruit fly)
          Length = 396

 Score =  214 bits (522), Expect = 2e-54
 Identities = 103/217 (47%), Positives = 146/217 (67%), Gaps = 7/217 (3%)

Query: 6   DIMEKFADAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARA 65
           DI   FA+A+ +  +++V APMVRYSK+ FR LVR     L FTPM+++DS   + KAR 
Sbjct: 11  DIAAMFAEAQSD--FVRVSAPMVRYSKLEFRRLVRLNGVQLAFTPMMISDSINNSEKARQ 68

Query: 66  NEFMTTTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLS 125
           NEF T   D P+IAQFAA +  +FV +++L+YPYVDG+DLNCGCPQ WAM  GYGC +L 
Sbjct: 69  NEFSTGADDQPLIAQFAAKDPTEFVTSAQLIYPYVDGIDLNCGCPQSWAMAKGYGCGMLR 128

Query: 126 KPEIIYDIVKGLRNVLPNKFSISVKIRLL---NDIKKTVILCQQLEKCGVTFLT--SMEE 180
           +PE+++ +V+ +R  LP  FS+SVK+RLL     +++T+ L +QLE  GVTFLT      
Sbjct: 129 QPELVHQVVQEVRRTLPGDFSVSVKMRLLGGEESLQRTIDLARQLESAGVTFLTLHGRTP 188

Query: 181 HCTKSSGPVDINGLKEVREALSVPMVANGGVKHLNDA 217
               S   +DI  + +VR++L +P++ NG V+   DA
Sbjct: 189 AQKHSKDTLDIPAMSQVRQSLQIPLIVNGNVESYRDA 225


>UniRef50_Q54ES7 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 344

 Score =  177 bits (431), Expect = 2e-43
 Identities = 83/199 (41%), Positives = 133/199 (66%), Gaps = 3/199 (1%)

Query: 20  YLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIA 79
           ++K+ APMVR+S++ FR LV+ +  D+ +TPMI+A  F ++  AR ++F     D P+I 
Sbjct: 55  FMKIQAPMVRFSRLPFRMLVKKWGCDITYTPMIMAAEFNRSEAARDSDFTINKLDEPLIV 114

Query: 80  QFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139
           QF  NN ++ V A++ V  Y  G+D+NCGCPQ+W MK+G+G +LL  PE IYD+VK + N
Sbjct: 115 QFGVNNAEELVSAAEKVKDYCQGIDINCGCPQRWVMKEGFGANLLLHPERIYDMVKQINN 174

Query: 140 VLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVR 198
            +P    IS+KIR+ +D+K T+ L ++ E+ GV+++T        KSS PVD + +K V+
Sbjct: 175 RVP--IPISIKIRVQSDLKDTIELAKRAERIGVSWITVHGRTSAMKSSHPVDYDAIKLVK 232

Query: 199 EALSVPMVANGGVKHLNDA 217
           + +++P+ ANG V  L+ +
Sbjct: 233 DNVTLPVFANGDVFTLSQS 251


>UniRef50_Q09504 Cluster: Uncharacterized tRNA-dihydrouridine
           synthase-like protein C45G9.2; n=2; Caenorhabditis|Rep:
           Uncharacterized tRNA-dihydrouridine synthase-like
           protein C45G9.2 - Caenorhabditis elegans
          Length = 284

 Score =  174 bits (424), Expect = 1e-42
 Identities = 85/192 (44%), Positives = 130/192 (67%), Gaps = 1/192 (0%)

Query: 27  MVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAANNR 86
           MVRYSK+ FR LVR ++ D+CFTPMI A +F ++ K R++E      D P+I QFA ++ 
Sbjct: 1   MVRYSKLAFRQLVRVYDVDVCFTPMIYAKNFIESEKCRSSELSVCEGDSPLIVQFATDDP 60

Query: 87  DDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN-KF 145
               +A+++VY    GVDLNCGCP+      G+G +LLSKPE++ D+V+  R  +P+  F
Sbjct: 61  FVLSEAAEMVYKCSTGVDLNCGCPKHDVRSKGFGSALLSKPELLADMVRQTRARIPDPDF 120

Query: 146 SISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSGPVDINGLKEVREALSVPM 205
           S+S+KIR+ +DI+KTV LC++ E  GVT LT      ++ + P+DI  L+ V++++SVP+
Sbjct: 121 SVSLKIRINHDIEKTVDLCRKAEAAGVTHLTVHGRTPSQRAEPIDIQALRIVKDSVSVPI 180

Query: 206 VANGGVKHLNDA 217
           +ANGG+    +A
Sbjct: 181 IANGGITTREEA 192


>UniRef50_O74553 Cluster: tRNA dihydrouridine synthase Dus4; n=1;
           Schizosaccharomyces pombe|Rep: tRNA dihydrouridine
           synthase Dus4 - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 326

 Score =  170 bits (413), Expect = 3e-41
 Identities = 85/206 (41%), Positives = 127/206 (61%), Gaps = 2/206 (0%)

Query: 10  KFADAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFM 69
           K  +    K  + + APMVRYSK+ FR LVR++N D+ +TPMILA  F  + K R  +F 
Sbjct: 10  KIFEINKGKRPVHIAAPMVRYSKLPFRQLVRDYNTDIVYTPMILAKEFL-HPKGRYFDFS 68

Query: 70  TTTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129
           T   D  +I QF  ++      A++LV PYVDG+ +NCGCPQ WA+++G G +LL +PE 
Sbjct: 69  TNDADASLILQFGVDDPVILEKAAQLVGPYVDGIGINCGCPQTWAIQEGIGSALLDEPEK 128

Query: 130 IYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGP 188
           ++ +V+ +++ L   F   VKIR+  D+ KT  L Q +EK G   +T        +SS P
Sbjct: 129 VHKLVRAVKSTLGESFCTEVKIRIAKDLNKTRHLMQVIEKSGADIITVHGRTRQDRSSFP 188

Query: 189 VDINGLKEVREALSVPMVANGGVKHL 214
           V+++ ++EVR  + +P+VANG VK L
Sbjct: 189 VNLDAIREVRPCVQIPVVANGDVKSL 214


>UniRef50_A7EMF2 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 342

 Score =  154 bits (373), Expect = 2e-36
 Identities = 82/213 (38%), Positives = 123/213 (57%), Gaps = 6/213 (2%)

Query: 11  FADAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMT 70
           F  AK     L  CAPMVRYSK+ FR  V  +  DLC+TPMILA  F ++  AR ++F T
Sbjct: 21  FDIAKQEGRPLYTCAPMVRYSKLAFRETVAQYGVDLCWTPMILAKEFNRSVFARDSDFTT 80

Query: 71  TTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEII 130
           + T  P IAQF   +  +   ++ L+ PY++G+D+NCGCPQ WA     G +L+ K E++
Sbjct: 81  SPTSTPTIAQFGVCSPLEISRSTTLIAPYINGIDINCGCPQSWACACSIGAALMHKRELV 140

Query: 131 YDIVKGLRNVL-----PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTK 184
            ++VK  ++ L       K ++SVKIR+  D++ TV   + ++  GV F+T       T 
Sbjct: 141 AEMVKEAKSALKREGYEGKKTVSVKIRIHRDLRDTVDFIKTVQDAGVDFITIHGRMRSTP 200

Query: 185 SSGPVDINGLKEVREALSVPMVANGGVKHLNDA 217
           SS PV++  +K +    +VP V+NG +  L  A
Sbjct: 201 SSHPVNLEAIKLLNTHTTVPTVSNGDITSLRSA 233


>UniRef50_Q5A4Y0 Cluster: Potential tRNA dihydrouridine synthase;
           n=2; Saccharomycetales|Rep: Potential tRNA
           dihydrouridine synthase - Candida albicans (Yeast)
          Length = 339

 Score =  153 bits (371), Expect = 3e-36
 Identities = 73/196 (37%), Positives = 121/196 (61%), Gaps = 2/196 (1%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           +  PMVRYSK+ FR L R ++ D+ +TPMILA  F +N  AR+ +F T  +D  VI Q  
Sbjct: 29  IAGPMVRYSKLPFRELCRFYDVDIVYTPMILAREFVRNEVARSTDFTTNDSDKCVIVQVG 88

Query: 83  ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
            NN DDF+   ++++P+VDG+ +NCGCP K  +++G G +L+S P+++ +++K  ++   
Sbjct: 89  VNNVDDFMKFIEMIHPFVDGIGINCGCPIKEQVREGIGAALMSDPDLVAELIKTAKDKYG 148

Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE-A 200
           +   I  KIR+  DI +T+    ++ + G   LT       T+SS PV+++ +K +RE  
Sbjct: 149 DSICIDTKIRIHRDINQTIDFVNKVVEAGTDTLTVHGRTKNTRSSVPVNLDAIKIIRENV 208

Query: 201 LSVPMVANGGVKHLND 216
            ++P++ANG    L D
Sbjct: 209 TTIPVIANGDCFTLTD 224


>UniRef50_Q06063 Cluster: tRNA-dihydrouridine synthase 4; n=10;
           Saccharomycetales|Rep: tRNA-dihydrouridine synthase 4 -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 367

 Score =  146 bits (354), Expect = 4e-34
 Identities = 72/198 (36%), Positives = 118/198 (59%), Gaps = 4/198 (2%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           +  PMVRYSK+ FR L R +N D+ ++PMILA  + +N  AR ++  T   D P+I Q  
Sbjct: 42  IAGPMVRYSKLPFRQLCREYNVDIVYSPMILAREYVRNEHARISDLSTNNEDTPLIVQVG 101

Query: 83  ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
            NN  D +   ++V PY DG+ +NCGCP K  +++G GC+L+   +++  +V  +++   
Sbjct: 102 VNNVADLLKFVEMVAPYCDGIGINCGCPIKEQIREGIGCALIYNSDLLCSMVHAVKDKYG 161

Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREAL 201
           +K  I  KIR+   + +TV LC++L   GV ++T       T+SS P +++ +K + E +
Sbjct: 162 DKLRIETKIRIHEALDETVELCRKLCDAGVDWITIHGRTRRTRSSQPANLDAIKYIIENI 221

Query: 202 S---VPMVANGGVKHLND 216
           S   VP++ANG    L+D
Sbjct: 222 SDKNVPVIANGDCFKLSD 239


>UniRef50_Q583Y8 Cluster: TRNA-dihydrouridine synthase 4, putative;
           n=3; Trypanosoma|Rep: TRNA-dihydrouridine synthase 4,
           putative - Trypanosoma brucei
          Length = 419

 Score =  145 bits (351), Expect = 9e-34
 Identities = 79/210 (37%), Positives = 124/210 (59%), Gaps = 8/210 (3%)

Query: 10  KFADAKINKTY---LKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARAN 66
           ++A  ++ K Y   LK+ APMVR S+  FR L R +  D+ +T MI+ADSF  +  AR  
Sbjct: 46  EWACQRMEKAYGSILKIQAPMVRCSRPAFRKLCRLWGTDISYTHMIMADSFACSEAARQA 105

Query: 67  EFMTTTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSK 126
           EF   + +  +I Q A+++      A+ +V P+ D +DLNCGCPQ+  M DG G +LL  
Sbjct: 106 EFSIYSGETRLITQLASSSGPTAATAAAIVAPWCDAIDLNCGCPQRRVMADGLGAALLRN 165

Query: 127 PEIIYDIVKGLRNVLPNKFSIS--VKIRLLNDIKKTVILCQQLEKCGVTFLT--SMEEHC 182
           PE++ D V+ +RN L     +   VK+R+ +D++ +V   +Q E  G  ++T      +C
Sbjct: 166 PEVVADTVRCVRNALEGGVELPCVVKMRVKDDVRLSVDFARQCEAAGAAWITVHGRTPNC 225

Query: 183 TKSSGPVDINGLKEVREALSVPMVANGGVK 212
           + +  PV  + +  +REAL VP+VANGGV+
Sbjct: 226 S-AHAPVRFDAINTIREALGVPVVANGGVR 254


>UniRef50_Q4Q391 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 493

 Score =  134 bits (325), Expect = 1e-30
 Identities = 82/225 (36%), Positives = 127/225 (56%), Gaps = 27/225 (12%)

Query: 20  YLKVC---APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP 76
           Y  +C   APMVR S+  FR + R +   + +T M++A+SF ++  AR  EF     +  
Sbjct: 93  YCSLCLIQAPMVRCSRPAFRQVCRAWGTRVSYTHMLMAESFVKSPHARHAEFARYEGENR 152

Query: 77  VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136
           ++AQ AA +      A+ L+ PY DG+DLNCGCPQ+WAMK+G G +LL +PE + D+V+ 
Sbjct: 153 LVAQLAAKSGPAAAQAALLLRPYCDGIDLNCGCPQRWAMKEGIGAALLDQPERVADMVRS 212

Query: 137 LRNVLPN------------KFS-----------ISVKIRLLNDIKKTVILCQQLEKCGVT 173
           +RN +P+            ++S             VK+R+ +D++++V   +Q E  GV+
Sbjct: 213 IRNAMPDGSTAPMIVGNGGEYSSCTSAVPPFLPCVVKMRIKDDLRRSVDFARQCEAAGVS 272

Query: 174 FLTSMEEHCT-KSSGPVDINGLKEVREALSVPMVANGGVKHLNDA 217
           +LT      T  SS  V    +K +RE LSVP+V NGGV  ++ A
Sbjct: 273 WLTVHGRTPTCHSSTAVQFEAVKLIRENLSVPVVLNGGVTDVSTA 317


>UniRef50_A5K1E0 Cluster: tRNA-dihydrouridine synthase, putative;
           n=5; Plasmodium|Rep: tRNA-dihydrouridine synthase,
           putative - Plasmodium vivax
          Length = 340

 Score =  128 bits (310), Expect = 8e-29
 Identities = 74/199 (37%), Positives = 112/199 (56%), Gaps = 8/199 (4%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           + APMV  S++ FR L RN+N  L FTPM+ A +F ++ K R + F +   D PVIAQF 
Sbjct: 29  ILAPMVDLSELAFRLLCRNYNCHLTFTPMLHAKNFVEHEKYRKSYFQSCEKDEPVIAQFC 88

Query: 83  ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
            NN    ++A + +   V+ VDLN GCPQ+ A K  YG  LL K + + ++V  + N   
Sbjct: 89  GNNSKIILNAIEYIKNEVNAVDLNLGCPQQIAKKGNYGAFLLQKHDEVVNLVSDITNNC- 147

Query: 143 NKFSISVKIRLLN-DIKKTVILCQQLEKCGVTFLT----SMEEHCTKSSGPVDINGLKEV 197
               I+ KIR ++ D +KT+ LC  L+   V  +T    + EE  T      D   +K +
Sbjct: 148 -NIPITCKIRKIDQDYQKTLNLCYDLQSRNVKMITVHGRTKEEKGTNIK-QCDYEIIKII 205

Query: 198 REALSVPMVANGGVKHLND 216
           +E L++P++ANG ++H  D
Sbjct: 206 KERLNIPIIANGSIEHFED 224


>UniRef50_Q54XQ6 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 435

 Score =  127 bits (307), Expect = 2e-28
 Identities = 73/202 (36%), Positives = 109/202 (53%), Gaps = 5/202 (2%)

Query: 18  KTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPV 77
           K+  K  APMV ++ + FR L R + AD+ +TPM  + +F      R + + T   D P+
Sbjct: 50  KSPKKTVAPMVDHTFLAFRMLCRKYGADMVYTPMFHSKNFATCKTYRRDYWSTCPEDRPL 109

Query: 78  IAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGL 137
           + QF  N  +  V A+K +  + D +DLN GCPQ+ A +  YG  LL KP II  IV+ L
Sbjct: 110 VVQFCGNEPEWVVKAAKYIEDHCDAIDLNLGCPQQIARRGNYGSFLLDKPHIILPIVQEL 169

Query: 138 RNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVDINGL 194
              +  K  I  KIRLL ++  T+ L  QL++ G   LT     +E    +SG  +   +
Sbjct: 170 HKHI--KVPIFCKIRLLPNLDDTIKLALQLQEAGCQLLTIHGRTKEQKGHNSGIANWKAI 227

Query: 195 KEVREALSVPMVANGGVKHLND 216
           + +RE LS+P++ANG V    D
Sbjct: 228 RTIREQLSIPVIANGSVVQYED 249


>UniRef50_Q9FH91 Cluster: Gb|AAF51525.1; n=6; Magnoliophyta|Rep:
           Gb|AAF51525.1 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 423

 Score =  123 bits (297), Expect = 3e-27
 Identities = 67/203 (33%), Positives = 108/203 (53%), Gaps = 5/203 (2%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           + APMV  S++ FR L + + A   +TPM+ +  F +  K R  EF T   D P+  QF 
Sbjct: 91  IVAPMVDNSELPFRLLCQKYGAQAAYTPMLHSRIFTETEKYRNQEFTTCKEDRPLFVQFC 150

Query: 83  ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
           AN+ D  ++A+K V PY D VD+N GCPQ+ A +  YG  L+    ++  +V+ L   L 
Sbjct: 151 ANDPDTLLEAAKRVEPYCDYVDINLGCPQRIARRGNYGAFLMDNLPLVKSLVEKLAQNL- 209

Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSGP---VDINGLKEVRE 199
               +S KIR+  +++ T+   + LE  G + L        +  G     D + +KEV+ 
Sbjct: 210 -NVPVSCKIRIFPNLEDTLKYAKMLEDAGCSLLAVHGRTRDEKDGKKFRADWSAIKEVKN 268

Query: 200 ALSVPMVANGGVKHLNDATTYMK 222
           A+ +P++ANG V+ + D    +K
Sbjct: 269 AMRIPVLANGNVRCIEDVDNCIK 291


>UniRef50_Q9VPM1 Cluster: CG3645-PA, isoform A; n=2; Diptera|Rep:
           CG3645-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 505

 Score =  123 bits (297), Expect = 3e-27
 Identities = 69/197 (35%), Positives = 106/197 (53%), Gaps = 5/197 (2%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           V APMV  S++ +R L R + A+LC++PM  A+ F  + K R +   T   D P+I QF 
Sbjct: 31  VVAPMVDQSELAWRMLCRRYGAELCYSPMYHANLFATDPKYRKDALQTCPEDRPLIIQFC 90

Query: 83  ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
            N+    +DA+ L   + D VD+N GCPQ  A +  YG  L  + E++ +IV  L   L 
Sbjct: 91  GNDAQQILDAALLAQDHCDAVDINLGCPQAIAKRGHYGSFLQDEWELLTEIVSTLHAKL- 149

Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVDINGLKEVRE 199
               ++ KIR+  D++KT+   + LE  G   LT      E     +G  + N +K VR+
Sbjct: 150 -AVPVTCKIRIFEDLEKTIRYAKMLEAAGCQLLTVHGRTREQKGPLTGVANWNYIKNVRQ 208

Query: 200 ALSVPMVANGGVKHLND 216
            + +PM+ANG +  L+D
Sbjct: 209 HIKIPMLANGNILALDD 225


>UniRef50_A7AQM0 Cluster: Dihydrouridine synthase, putative; n=1;
           Babesia bovis|Rep: Dihydrouridine synthase, putative -
           Babesia bovis
          Length = 355

 Score =  122 bits (295), Expect = 5e-27
 Identities = 68/199 (34%), Positives = 109/199 (54%), Gaps = 7/199 (3%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           V APMV  S++ FR L R +N DL +TPM+    F +N K RA  F T+  D P+IAQ  
Sbjct: 15  VAAPMVNQSELPFRLLCRRYNVDLTYTPMLHGRIFVENEKYRAVHFQTSDDDRPLIAQVC 74

Query: 83  ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
            ++      A++L+  +V  VDLN GCPQ  A    YG  LL +P+++  IV  +   + 
Sbjct: 75  GDDAGTITQAARLLKGHVSAVDLNLGCPQAIAKDGHYGSFLLDEPDLVTGIVSRVTREV- 133

Query: 143 NKFSISVKIRLL--NDIKKTVILCQQLEKCGVTFLTSMEEHCTKSS---GPVDINGLKEV 197
              +++ KIR +  + ++ T+ LC  LE+ G   LT    H ++     G  D + ++ +
Sbjct: 134 -GIAVTCKIRKVDKDSLQSTLNLCYSLEQSGCKALTVHGRHRSEKGTNVGAADWDAIRII 192

Query: 198 REALSVPMVANGGVKHLND 216
           +  L +P++ANGG++   D
Sbjct: 193 KSRLRIPVIANGGIETFAD 211


>UniRef50_Q9XVN8 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 527

 Score =  122 bits (293), Expect = 9e-27
 Identities = 75/211 (35%), Positives = 111/211 (52%), Gaps = 7/211 (3%)

Query: 17  NKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP 76
           N+   KV APMV  S++ FR   R + A L FTPMI A  F  +   R N       D P
Sbjct: 70  NQRITKVLAPMVDQSELAFRMFTRKYGAQLTFTPMIHAHLFVNDGTYRRNSLALVKADRP 129

Query: 77  VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136
           ++ QF AN  D F+ A +LV    DGVDLN GCPQ  A +  YG  L  + ++I ++V  
Sbjct: 130 LVVQFCANKVDTFLAACRLVEDVCDGVDLNLGCPQMVAKRGRYGSWLQDEVDLICEMVSA 189

Query: 137 LRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVDING 193
           +R+    +  IS KIR+ +D ++TV   ++L   G T LT      +     +G  D + 
Sbjct: 190 VRDYC--RLPISCKIRVRDDRQQTVEYAKRLVDAGATMLTVHGRTRDMKGAETGLADWSR 247

Query: 194 LKEVREALS--VPMVANGGVKHLNDATTYMK 222
           +++V EA+   VP++ANG ++   D    M+
Sbjct: 248 IRDVVEAVGSRVPVMANGNIQFPGDVERCMQ 278


>UniRef50_Q5KPM6 Cluster: Putative uncharacterized protein; n=2;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 407

 Score =  121 bits (292), Expect = 1e-26
 Identities = 61/145 (42%), Positives = 94/145 (64%), Gaps = 5/145 (3%)

Query: 77  VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136
           +IAQFA+ N     DA++L+ PYVDG+DLNCGCPQ+WA  +G GC+LL KPE++ D+V+G
Sbjct: 152 LIAQFASPNAKSLADAAELISPYVDGIDLNCGCPQRWAYNEGIGCALLRKPELVRDMVRG 211

Query: 137 LRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT--SMEEHCTKSSGPVDINGL 194
           +++ +   + +S+KIR+ ++ +KT  L     + G++ LT      H   S+ PV++ G+
Sbjct: 212 VKDRMGWGWPVSIKIRIDSEQEKTEQLISNALQAGISHLTIHGRTRH-QPSTDPVNLPGI 270

Query: 195 KEVREAL--SVPMVANGGVKHLNDA 217
           K   + +   VP VANG V  L DA
Sbjct: 271 KFAVDCVKGEVPCVANGDVWELEDA 295



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 21/52 (40%), Positives = 32/52 (61%)

Query: 23 VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTD 74
          V AP+VR SK+ FR L   +   +  TPMILA+ F +   AR ++F T++ +
Sbjct: 35 VLAPLVRCSKLPFRHLTSLYETHITHTPMILAEEFSRAQIARTSDFSTSSNE 86


>UniRef50_A4S141 Cluster: Predicted protein; n=1; Ostreococcus
           lucimarinus CCE9901|Rep: Predicted protein -
           Ostreococcus lucimarinus CCE9901
          Length = 307

 Score =  121 bits (291), Expect = 2e-26
 Identities = 65/197 (32%), Positives = 113/197 (57%), Gaps = 7/197 (3%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           APMV  S++ FR L + + A L +TPMI A  F ++ K R   F T+T D P++AQF AN
Sbjct: 21  APMVDQSELAFRELCKRYGATLGYTPMIHARLFVESPKYRREIFSTSTRDRPLLAQFCAN 80

Query: 85  NRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNK 144
           + +  + A+ ++ PY DGVD+N GCPQ+ A +  YG  L+   + +  +++ L   LP  
Sbjct: 81  DPEILLRAATMIAPYCDGVDINFGCPQRIAKRGNYGAFLMDDWKTVEALIRKLDEELP-- 138

Query: 145 FSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSGPVDING----LKEVREA 200
             ++ KIR+ +D++ T+   + +E  G   + ++     +     DI      ++ +++A
Sbjct: 139 VPVTAKIRVYDDLETTLKYAKMVEAAGAQ-IVAVHGRTREQKRCADIRANWAYIRAIKDA 197

Query: 201 LSVPMVANGGVKHLNDA 217
           L VP++ANG ++ L +A
Sbjct: 198 LKVPVLANGDIRSLAEA 214


>UniRef50_Q5CSA9 Cluster: Dus1p, tRNA dihydrouridine synthase; n=2;
           Cryptosporidium|Rep: Dus1p, tRNA dihydrouridine synthase
           - Cryptosporidium parvum Iowa II
          Length = 409

 Score =  117 bits (282), Expect = 2e-25
 Identities = 67/199 (33%), Positives = 105/199 (52%), Gaps = 6/199 (3%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           V APMV  S++ FR + + +  DL ++PM  +  F +    R   F T   D P+I QF 
Sbjct: 22  VLAPMVDGSELAFRLICKKYGCDLGYSPMYHSGLFSKLQGYRETNFQTCEEDDPMIVQFC 81

Query: 83  ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
            N+ +  V ASK +   V G+D+N GCPQ  A +  YG  LLS P+++  I+  L +   
Sbjct: 82  GNDPETLVKASKFIDDKVKGIDINFGCPQNIAKRGNYGAFLLSNPDLMERIISTL-SESD 140

Query: 143 NKFSISVKIRLL--NDIKKTVILCQQLEKCGVTFLTSMEEHCTKS---SGPVDINGLKEV 197
            K  +S KIR+L  +D++ T+ L ++LE  G   +       T     +GP +   LK +
Sbjct: 141 LKCPVSCKIRILDHHDLQPTINLIKRLESAGACMIAVHGRTMTSRGVLTGPANWEALKIL 200

Query: 198 REALSVPMVANGGVKHLND 216
           +   S+P +ANGG+ +  D
Sbjct: 201 KSRCSIPFIANGGISNYED 219


>UniRef50_Q6P1R4 Cluster: tRNA-dihydrouridine synthase 1-like; n=20;
           Euteleostomi|Rep: tRNA-dihydrouridine synthase 1-like -
           Homo sapiens (Human)
          Length = 473

 Score =  115 bits (277), Expect = 8e-25
 Identities = 73/201 (36%), Positives = 106/201 (52%), Gaps = 11/201 (5%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTT--DFPVIAQ 80
           V APMV  S++ +R L R   A LC+TPM+ A  F +++  R           D P+I Q
Sbjct: 20  VVAPMVDQSELAWRLLSRRHGAQLCYTPMLHAQVFVRDANYRKENLYCEVCPEDRPLIVQ 79

Query: 81  FAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140
           F AN+ + FV A+ L   Y D +DLN GCPQ  A +  YG  L  +    +D+++ +  +
Sbjct: 80  FCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQDE----WDLLQRMILL 135

Query: 141 LPNKFSISV--KIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVDINGLK 195
              K S+ V  KIR+  +I KTV   Q LEK G   LT     +E     SG      +K
Sbjct: 136 AHEKLSVPVTCKIRVFPEIDKTVRYAQMLEKAGCQLLTVHGRTKEQKGPLSGAASWEHIK 195

Query: 196 EVREALSVPMVANGGVKHLND 216
            VR+A+++P+ ANG ++ L D
Sbjct: 196 AVRKAVAIPVFANGNIQCLQD 216


>UniRef50_A0EG06 Cluster: Chromosome undetermined scaffold_94, whole
           genome shotgun sequence; n=4; Intramacronucleata|Rep:
           Chromosome undetermined scaffold_94, whole genome
           shotgun sequence - Paramecium tetraurelia
          Length = 360

 Score =  112 bits (269), Expect = 8e-24
 Identities = 66/198 (33%), Positives = 104/198 (52%), Gaps = 7/198 (3%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTT-DFPVIAQF 81
           +CAPMV  S++ FR L R +   L +TPM L       SK+  +EF TT   D P+ AQ 
Sbjct: 21  ICAPMVDQSELAFRMLTRKYGTTLAYTPM-LHSRIMTESKSYKDEFFTTCPEDRPLFAQL 79

Query: 82  AANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141
             ++    + A+ ++    D +D+N GCPQ  A K  YG  LL K E +  IVK L+  +
Sbjct: 80  CGHDPQVLIKAALMIQDQCDAIDINLGCPQGIARKGLYGAYLLEKREQVLTIVKELKQNI 139

Query: 142 PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVDINGLKEVR 198
                ++ KIR+  D K+T+ L + +++ G + LT     +E      G  D   + E++
Sbjct: 140 --NVPVTCKIRMFKDRKRTLDLTKDIQEAGCSILTVHGRTKEQNKDFVGQCDWTIIAEIK 197

Query: 199 EALSVPMVANGGVKHLND 216
           + L +P+ ANGG+   +D
Sbjct: 198 QILQIPVFANGGIYTWSD 215


>UniRef50_A2FU21 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 322

 Score =  110 bits (265), Expect = 2e-23
 Identities = 60/209 (28%), Positives = 114/209 (54%), Gaps = 10/209 (4%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           V AP    + + FR LVR +N  LC+T M+ +  +     +R + F T + D P+I Q +
Sbjct: 19  VLAPQFEVNDLAFRMLVRKYNVKLCWTGMVNSHMWAIQPSSRNSYFQTCSQDRPLIIQMS 78

Query: 83  ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
            N+  + +  +K +  +  G+D+NCGC Q  A +  YG  +++      ++++ ++N++ 
Sbjct: 79  GNDESELIACAKDLQQFAVGIDINCGCTQHIARRGQYGYFMVNNENKRKNVIEMVKNIVA 138

Query: 143 N-KFSISVKIRLLN------DIKKTVILCQQLEKCGVTFLTSMEEHCTKS--SGPVDING 193
           +    +S+K RL++      D+  T    ++LE  GV+ L S+      S  +GPVD   
Sbjct: 139 SINVPLSIKFRLIDGEDGKPDVDITCKFAKELEDAGVS-LISVHGRAKNSNKAGPVDAEA 197

Query: 194 LKEVREALSVPMVANGGVKHLNDATTYMK 222
           ++++ E++S+P++ANGGV+   +A    K
Sbjct: 198 IRKIAESVSIPVMANGGVRTKEEAIEMFK 226


>UniRef50_UPI000023CFE7 Cluster: hypothetical protein FG01258.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG01258.1 - Gibberella zeae PH-1
          Length = 362

 Score =  105 bits (252), Expect = 9e-22
 Identities = 57/133 (42%), Positives = 75/133 (56%), Gaps = 2/133 (1%)

Query: 11  FADAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANE--F 68
           F  A+    +L   APMVRY K+ FR  V  +  DLC++PMILA  F ++S AR ++  F
Sbjct: 16  FDIARKQDRFLYALAPMVRYGKLAFRQTVHKYGVDLCWSPMILAKEFNRSSFARDSDWSF 75

Query: 69  MTTTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPE 128
            T     P I QF AN   +   AS LV P   GVDLNCGCPQ WA  +  G +L++  E
Sbjct: 76  STEPKQPPTIVQFGANVPLELARASALVAPSSQGVDLNCGCPQSWACAETLGAALMNHRE 135

Query: 129 IIYDIVKGLRNVL 141
           ++ D+V   R  L
Sbjct: 136 LVRDMVVETRQRL 148


>UniRef50_Q4UGK9 Cluster: Putative uncharacterized protein; n=2;
           Theileria|Rep: Putative uncharacterized protein -
           Theileria annulata
          Length = 359

 Score =  104 bits (249), Expect = 2e-21
 Identities = 66/195 (33%), Positives = 101/195 (51%), Gaps = 11/195 (5%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           + APMV  S++ FR L R ++ADL +TPM+ A  F +N   R   F T++ D P+IAQF 
Sbjct: 29  IVAPMVDQSELPFRLLCRRYSADLAYTPMLHAKIFSENENYRNIHFHTSSDDKPLIAQFC 88

Query: 83  ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
            N+   F+ AS  +   V  +D+N GCPQ  A K  YG  LL  P++   I KG  +V  
Sbjct: 89  GNDPSAFILASSYIKNDVSAIDINLGCPQGIAKKGRYGSFLLEYPQL---ITKGFASV-D 144

Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSS-GPVDINGLKEVREAL 201
            KF +  +  L      +V  C Q   C    +       TK+     D + +K ++  +
Sbjct: 145 TKFMLFTRGWLF-----SVQSC-QANGCKALTVHGRHRSETKTRISECDWDSIKIIKSRV 198

Query: 202 SVPMVANGGVKHLND 216
           ++P++ANGG++   D
Sbjct: 199 NIPVIANGGIETFED 213


>UniRef50_P53759 Cluster: tRNA-dihydrouridine synthase 1; n=11;
           Saccharomycetales|Rep: tRNA-dihydrouridine synthase 1 -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 423

 Score =  103 bits (247), Expect = 4e-21
 Identities = 65/209 (31%), Positives = 113/209 (54%), Gaps = 10/209 (4%)

Query: 22  KVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMT---TTTDFPVI 78
           ++ APMV  S++ +R L R + A L +TPM+ A  F  + K R + + +   ++ D P++
Sbjct: 31  RIVAPMVDQSELAWRILSRRYGATLAYTPMLHAKLFATSKKYREDNWSSLDGSSVDRPLV 90

Query: 79  AQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLR 138
            QF AN+ +  + A+KLV    D VDLN GCPQ  A K  YG  L+ + ++I++++  L 
Sbjct: 91  VQFCANDPEYLLAAAKLVEDKCDAVDLNLGCPQGIAKKGHYGSFLMEEWDLIHNLINTLH 150

Query: 139 NVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVDINGLK 195
             L  K  ++ KIR+ +D +K++   + +   G  FLT    + E   + +G  +   +K
Sbjct: 151 KNL--KVPVTAKIRIFDDCEKSLNYAKMVLDAGAQFLTVHGRVREQKGQKTGLANWETIK 208

Query: 196 EVREALSVPMV--ANGGVKHLNDATTYMK 222
            +R+ L    V  ANG + +  D +  M+
Sbjct: 209 YLRDNLPKETVFFANGNILYPEDISRCME 237


>UniRef50_UPI0000499E32 Cluster: conserved hypothetical protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
           hypothetical protein - Entamoeba histolytica HM-1:IMSS
          Length = 339

 Score =  101 bits (243), Expect = 1e-20
 Identities = 60/197 (30%), Positives = 103/197 (52%), Gaps = 12/197 (6%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTT--DFPVIAQ 80
           + APMV  S + FR LVR    +LC+TPM+L+  F + SK   NE + +    + P+I Q
Sbjct: 25  ILAPMVDGSDLTFRILVRRHGVNLCYTPMVLSKMFVE-SKVYRNEVVNSLDPKEQPIIIQ 83

Query: 81  FAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140
              ++ ++    +K +  Y D +D+N GCPQK A K  YG  L     + +D  K + N 
Sbjct: 84  IVGSDANEMARTAKFLQSYCDAIDINLGCPQKIAQKGNYGAYL----ALDFDHTKEIVNA 139

Query: 141 LPNKFSISV--KIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSG---PVDINGLK 195
           +    +I V  K+R+  D +KT+   + L++CG+  +       T+          N + 
Sbjct: 140 VIEAVNIPVYCKVRVFEDEEKTMRFVEMLQECGIWGIAVHGRTITEKQSMNYHARWNYIA 199

Query: 196 EVREALSVPMVANGGVK 212
           +++E L +P++ANG ++
Sbjct: 200 KIKERLKIPVIANGEMR 216


>UniRef50_Q9HGN6 Cluster: tRNA dihydrouridine synthase Dus1; n=1;
           Schizosaccharomyces pombe|Rep: tRNA dihydrouridine
           synthase Dus1 - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 399

 Score =  100 bits (239), Expect = 3e-20
 Identities = 65/208 (31%), Positives = 102/208 (49%), Gaps = 9/208 (4%)

Query: 22  KVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTT--DFPVIA 79
           ++ APMV  S++ +R L R   ADLC++PM  +  F ++   R   F T T   + P+I 
Sbjct: 20  RILAPMVDQSELPWRILARRSGADLCYSPMFHSRLFGESEDYRNKVFSTRTIPEERPLII 79

Query: 80  QFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139
           QF  N+ +  + A+K+  PY D VD+N GCPQ  A K  YG  L     +I  I+  L  
Sbjct: 80  QFCGNDPEIMLKAAKIAAPYCDAVDVNLGCPQGIAKKGKYGSFLQENWNLIESIITKLHT 139

Query: 140 VLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVDINGLKE 196
            L     ++ KIR+  D +KT+   + + K G + L     + E     +G  D   ++ 
Sbjct: 140 EL--SIPVTAKIRIFPDPQKTLDYAKMILKAGASILAVHGRLREQKGHFTGIADWEQIQM 197

Query: 197 VREAL--SVPMVANGGVKHLNDATTYMK 222
           +R+ L     + ANG + H  D    +K
Sbjct: 198 LRKNLPSETVLFANGNILHAQDIDRCIK 225


>UniRef50_A2EF32 Cluster: Dihydrouridine synthase, putative; n=1;
           Trichomonas vaginalis G3|Rep: Dihydrouridine synthase,
           putative - Trichomonas vaginalis G3
          Length = 318

 Score = 99.1 bits (236), Expect = 8e-20
 Identities = 69/212 (32%), Positives = 108/212 (50%), Gaps = 13/212 (6%)

Query: 23  VC-APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQF 81
           +C APM   S + +R L+RN    +C+T M+ A  + Q S  +   F T   D P+IAQ 
Sbjct: 20  ICLAPMAEISDLSWRMLIRNHGVKVCWTGMLNAHQWSQGSGYQNKFFNTCPEDHPLIAQI 79

Query: 82  AANNRDD--FVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139
           A +N D    V A+K +  Y DGVD+N GC QK A +  YG  ++   +     ++  R 
Sbjct: 80  AGSNEDQDLIVAAAKDLAKYADGVDVNLGCTQKIASRSEYGYFMVDNCQKREKTLELFRR 139

Query: 140 VLPN-KFSISVKIRLLND------IKKTVILCQQLEKCGVTFLT--SMEEHCTKSSGPVD 190
           +       I  KIR+  D       K T+   ++LE+ GV+ L      EH  K +  V 
Sbjct: 140 LCKEVNCPICAKIRIFIDDSGEVSEKITIDFAKKLEEAGVSLLQVHGRAEHRNKQA-DVY 198

Query: 191 INGLKEVREALSVPMVANGGVKHLNDATTYMK 222
              +K + +A+++P+VANGG+  + DA  +M+
Sbjct: 199 NEIIKHIVQAVNIPVVANGGINTVEDAHKFME 230


>UniRef50_Q8SUV4 Cluster: Putative uncharacterized protein
           ECU07_1610; n=1; Encephalitozoon cuniculi|Rep: Putative
           uncharacterized protein ECU07_1610 - Encephalitozoon
           cuniculi
          Length = 341

 Score = 99.1 bits (236), Expect = 8e-20
 Identities = 64/214 (29%), Positives = 113/214 (52%), Gaps = 9/214 (4%)

Query: 8   MEKFADAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARA-N 66
           M KF + +I + Y  V APMV  S+  +R L +   A++ +T M+  DSF + S+    N
Sbjct: 1   MRKFWE-EIQRPYFAV-APMVGNSEEAWRRLSKRHGANIFYTEMVHCDSFLRGSRNPVKN 58

Query: 67  EFMTTTT-DFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLS 125
            + TT+  D P++ Q   N+ +  ++A+ ++  + D +D+N GCPQK A K GYG  L  
Sbjct: 59  RWYTTSEGDRPLVVQICGNSPEVMLEAALIIQDHCDAIDVNFGCPQKVARKGGYGAYLQE 118

Query: 126 KPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHC 182
             ++  +IVK L + L     +  KIR+   I+KTV   + +E+ G + L       +  
Sbjct: 119 NWKLTGEIVKVLSSGL--NVPVFCKIRVFGSIEKTVEYAKMIEEAGCSLLAVHGRTRDQR 176

Query: 183 TKSSGPVDINGLKEVREALSVPMVANGGVKHLND 216
             + G      ++ ++E L +P+++NG +   +D
Sbjct: 177 GAAMGFASWKHIRAIKENLRIPVLSNGNIMTHHD 210


>UniRef50_Q8PX79 Cluster: NifR3-like protein; n=5; Archaea|Rep:
           NifR3-like protein - Methanosarcina mazei
           (Methanosarcina frisia)
          Length = 323

 Score = 98.3 bits (234), Expect = 1e-19
 Identities = 64/209 (30%), Positives = 104/209 (49%), Gaps = 8/209 (3%)

Query: 10  KFADAKINKTYLK---VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARAN 66
           K    KI +T L    + APM   + + FR L R + ADL +T MI  D+    S+    
Sbjct: 2   KLKKLKIGRTELSGNLLLAPMADVTNLAFRLLCRRYGADLTYTEMINVDALLNESRKSFI 61

Query: 67  EFMTTTTDFPVIAQFAANNRDDFVDASKLVYPYV--DGVDLNCGCPQKWAMKDGYGCSLL 124
           + +++  D P   Q      D    A+  +      + +D+N GCP +     G G +LL
Sbjct: 62  KGLSSEEDRPFGVQLVGGCPDKLKRAALFIEEEYRPEIIDVNMGCPARCITGAGCGSALL 121

Query: 125 SKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTK 184
           + PE++Y I+  L   L     +S KIRLL   +KT+ + + +EK G + +T       +
Sbjct: 122 NSPELVYSIILELTESLDT--PVSAKIRLLGREEKTLEIARLIEKAGASAVTVHGRTAAQ 179

Query: 185 S-SGPVDINGLKEVREALSVPMVANGGVK 212
             SG  ++ G++ V+  LS+P++ANG VK
Sbjct: 180 MYSGNSNLEGIRAVKNELSIPVIANGDVK 208


>UniRef50_A2DHB4 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 312

 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 62/203 (30%), Positives = 103/203 (50%), Gaps = 10/203 (4%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP--VIAQFA 82
           APM   +   FR L R     LC+T  I A  +   +K R  +   TT D    ++ Q  
Sbjct: 18  APMADVNDYSFRKLCRQNGVSLCWTGFINAHHWVTRTKQRDRDVWFTTRDNEKNLVVQLL 77

Query: 83  ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
            +N ++ V  +K V  + D ++LNCGC   +A + G G  L+   +     +  ++N++ 
Sbjct: 78  GSNLEELVSCAKDVENFCDMIELNCGCTHCFASRSGCGFFLIDTQKHRDSALILIQNLIK 137

Query: 143 N-KFSISVKIRLLND------IKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGL 194
           +    +S+KIRL++D      +++TV   Q LE+ GV+ +T           G VD + +
Sbjct: 138 SINKPVSIKIRLISDDNSVPSLERTVKFAQDLERVGVSLITVHARTQQADKKGDVDYDAI 197

Query: 195 KEVREALSVPMVANGGVKHLNDA 217
           K V +A+SVP++ANGG+  L  A
Sbjct: 198 KAVVQAVSVPVIANGGISSLEQA 220


>UniRef50_Q00RI1 Cluster: OSIGBa0125M19.5 protein; n=9;
           Magnoliophyta|Rep: OSIGBa0125M19.5 protein - Oryza
           sativa (Rice)
          Length = 319

 Score = 95.9 bits (228), Expect = 7e-19
 Identities = 68/211 (32%), Positives = 106/211 (50%), Gaps = 19/211 (9%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSF--CQ---NSKARANEFMTTTTDFPV 77
           V APMVR   + FR L   + AD+ +   I+   F  C+   N      +F+   TD  V
Sbjct: 8   VLAPMVRVGTLPFRLLAAEYGADITYGEEIIDHKFLKCERVTNESLGTTDFLERGTDTVV 67

Query: 78  -----------IAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSK 126
                      + Q   ++    + A++LV   V  +D+N GCP+ +++  G G +LLSK
Sbjct: 68  FRTCPQERDRVVFQMGTSDAVRALKAAQLVCNDVAAIDINMGCPKSFSLSGGMGAALLSK 127

Query: 127 PEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHC-TKS 185
           PE+I+DI+  LR  L    +++ KIRLLN  + TV L +++EK GV  L         + 
Sbjct: 128 PELIHDILTTLRRNLDT--TVTCKIRLLNTRQDTVELARRVEKIGVPALAVHGRKVKDRP 185

Query: 186 SGPVDINGLKEVREALSVPMVANGGVKHLND 216
             P   + + +V  ALS+P++ANG V    D
Sbjct: 186 RDPAKWDEIADVVSALSIPVIANGDVFEYED 216


>UniRef50_A6DCX2 Cluster: tRNA-dihydrouridine synthase B; n=1;
           Caminibacter mediatlanticus TB-2|Rep:
           tRNA-dihydrouridine synthase B - Caminibacter
           mediatlanticus TB-2
          Length = 311

 Score = 95.5 bits (227), Expect = 9e-19
 Identities = 57/193 (29%), Positives = 104/193 (53%), Gaps = 9/193 (4%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           AP+  Y+ + FR++V+ F  D+ F+ MI A++   N++        ++ + P   Q AAN
Sbjct: 16  APLAGYTDLPFRSVVKEFGCDMTFSEMINANAIAFNNEKTKKMMQKSSKETPYFIQIAAN 75

Query: 85  NRDDFVDASKLV--YPYVDGVDLNCGCPQKWAMKDGYGCSLL--SKPEIIYDIVKGLRNV 140
           N ++ + A +++   P++DG+D+N GCP   A + GYG  LL     E + +IV  +  +
Sbjct: 76  NVENAIKAVEIINEIPWIDGIDINLGCPVNKARRSGYGGVLLKDENKEKLKEIVSAI--I 133

Query: 141 LPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS--SGPVDINGLKEVR 198
             +K  +S K+RL  +    V   + LE  G+ FLT +     K    G  +   +K+V 
Sbjct: 134 KTSKKIVSAKMRLGYNEVVAVDRAKMLEDLGIKFLT-VHGRTVKQMYKGNANYKEIKKVV 192

Query: 199 EALSVPMVANGGV 211
           + +++P++ANG +
Sbjct: 193 KEVNIPVIANGDI 205


>UniRef50_A4RU69 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 345

 Score = 95.5 bits (227), Expect = 9e-19
 Identities = 66/210 (31%), Positives = 106/210 (50%), Gaps = 16/210 (7%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSF--CQ---NSKARANEFMTT--TTDF 75
           VCAPMVR S +  R L   + ADL +   ++   F  C+   N +  + +F+    T  F
Sbjct: 16  VCAPMVRISTLATRLLAHEYGADLVYGEELVDKRFMHCRRILNKELGSVDFIDAKGTLTF 75

Query: 76  --------PVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKP 127
                    V+ Q   ++    + +++LV   V  +D+N GCP+ ++   G G  LLS+P
Sbjct: 76  RTVPEERERVVFQVGTSSAASALKSAELVARDVAAIDVNMGCPKHFSTSGGMGARLLSQP 135

Query: 128 EIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVT-FLTSMEEHCTKSS 186
           E++ DI+  LR  LP+   ++ KIRLL   ++T  L + +E CGV+ F         +  
Sbjct: 136 ELVRDILTTLRRNLPSTTHVTCKIRLLESERETAELAKMIESCGVSAFAVHGRYIPQRPR 195

Query: 187 GPVDINGLKEVREALSVPMVANGGVKHLND 216
            P   N +K V EA+  P++ANG V+   D
Sbjct: 196 EPAHWNLIKNVVEAVDCPVIANGDVECYED 225


>UniRef50_Q4PBU9 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 477

 Score = 95.1 bits (226), Expect = 1e-18
 Identities = 47/120 (39%), Positives = 75/120 (62%), Gaps = 1/120 (0%)

Query: 77  VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136
           ++AQFA++  + F DAS+L+  +VDGVDLNCGCPQ WA ++  G  LL +PE + D+V+ 
Sbjct: 169 LVAQFASSKPEPFADASELIGRFVDGVDLNCGCPQPWAYEELLGSYLLRQPETVRDMVRA 228

Query: 137 LRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFL-TSMEEHCTKSSGPVDINGLK 195
           ++  + + F +SVKIR+  D++ T  L +     G + L          SS PV+++G+K
Sbjct: 229 VKARMGSDFCVSVKIRIDPDLRLTDALVRNALHAGASILQIHGRTRWQSSSEPVNLDGIK 288



 Score = 59.3 bits (137), Expect = 7e-08
 Identities = 28/50 (56%), Positives = 33/50 (66%)

Query: 21 LKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMT 70
          L VCAPMVRYSK+ FRTLV  +   +  TPMILA  F +   AR +EF T
Sbjct: 41 LNVCAPMVRYSKLAFRTLVSRYETHITTTPMILAKEFSRTEAARNSEFST 90


>UniRef50_Q57V78 Cluster: TRNA-dihydrouridine synthase 1, putative;
           n=1; Trypanosoma brucei|Rep: TRNA-dihydrouridine
           synthase 1, putative - Trypanosoma brucei
          Length = 520

 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 68/230 (29%), Positives = 107/230 (46%), Gaps = 33/230 (14%)

Query: 18  KTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTT----- 72
           +T + V  PMV  S++ FR L R + A L +TPM  A SF Q++  R   F TTT     
Sbjct: 71  RTPMYVVGPMVDQSELPFRLLCRRYGATLAYTPMFHAKSFAQSAHYRQRYFSTTTFPPHS 130

Query: 73  ---------------------TDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQ 111
                                 D P+ AQF  N+ +  + A++ V  Y + VD N GCPQ
Sbjct: 131 AMESGGNVAANDSTSNDGALDNDHPLFAQFCGNDPETVLAAARHVEDYCEAVDFNIGCPQ 190

Query: 112 KWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCG 171
             A +  YG  L+   E++++I+  L   L  +  ++ K+R+ +D   T+   + L   G
Sbjct: 191 GIARRGHYGSFLMEDWELLHNILHALAVEL--RVPVTAKMRIFDDEALTLKYAEMLRDTG 248

Query: 172 VTFLT---SMEEHCTKSSGPVDINGLKEVREAL--SVPMVANGGVKHLND 216
           +  L       E+  +   P D+  ++ V E L  S+P++ANG V    D
Sbjct: 249 IYVLCVHGRTRENKGQQQQPADLRMIRRVHEHLRGSIPIIANGNVLTFED 298


>UniRef50_UPI000023EA9A Cluster: hypothetical protein FG07217.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG07217.1 - Gibberella zeae PH-1
          Length = 510

 Score = 89.8 bits (213), Expect = 5e-17
 Identities = 60/173 (34%), Positives = 86/173 (49%), Gaps = 21/173 (12%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNAD------LCFTPMILADSFCQNSKARANEFMTTTTDF- 75
           + APMV  S+  +R L R+F +       L +TPM+ A  F Q+ K R   F    TD  
Sbjct: 31  IVAPMVDQSEFAWRMLTRSFISPTEQKSLLAYTPMLHARLFSQDDKYRKAHFQAVKTDGE 90

Query: 76  ------------PVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSL 123
                       P+  QF AN+ D  + A+K V PY D VDLN GCPQ  A K  YG  L
Sbjct: 91  TPWLDGNPSIDRPLFVQFCANDPDALLSAAKQVAPYCDAVDLNLGCPQGIARKGKYGAFL 150

Query: 124 LSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176
               ++I+ ++  L   LP    ++ KIR+L+  ++T+   Q + K G + LT
Sbjct: 151 QEDQDLIFRLINILHKELP--VPVTAKIRILDTKEETLAYAQNVLKAGASILT 201


>UniRef50_A6RW05 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 278

 Score = 89.0 bits (211), Expect = 8e-17
 Identities = 49/153 (32%), Positives = 83/153 (54%), Gaps = 6/153 (3%)

Query: 66  NEFMTTTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLS 125
           ++F T+ T  P IAQF   +  +   ++ L+ PYV+GVD+NCGCPQ WA     G +L+ 
Sbjct: 26  DDFTTSPTSGPTIAQFGVCSPLEISRSTTLLAPYVNGVDINCGCPQSWACACSIGAALMH 85

Query: 126 KPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTK 184
           K E++ ++VK  ++ L        K      +++T+     ++  GV F+T       T 
Sbjct: 86  KRELVAEMVKEAKSALKRDGFEGKK-----TVRETIDFINTVQDAGVDFITIHGRMRSTP 140

Query: 185 SSGPVDINGLKEVREALSVPMVANGGVKHLNDA 217
           SS PV++  +K +    +VP ++NG +  L+DA
Sbjct: 141 SSHPVNLEAIKLLTTHTTVPTLSNGDIFTLSDA 173


>UniRef50_Q6F288 Cluster: TRNA dihydrouridine synthetase; n=3;
           Mollicutes|Rep: TRNA dihydrouridine synthetase -
           Mesoplasma florum (Acholeplasma florum)
          Length = 325

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 57/193 (29%), Positives = 94/193 (48%), Gaps = 4/193 (2%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           V  PM   S   FR + +   ADL    M+  +    N+K   +       + P+  Q  
Sbjct: 13  VQGPMAGVSNPPFRLISKEKGADLVCAEMVSVEGMTHNNKKTFSMLAVEKKEHPMSMQIF 72

Query: 83  ANNRDDFVDASKLVYPYVDG--VDLNCGCPQ-KWAMKDGYGCSLLSKPEIIYDIVKGLRN 139
            N+ + F+ A+K +   VD   +DLN GCP  K A++   G SLL  PE+IYDIVK +  
Sbjct: 73  GNDVESFIVATKWIDENVDCDIIDLNIGCPAPKVAVRSASGSSLLKTPELIYDIVKAVVE 132

Query: 140 VLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTK-SSGPVDINGLKEVR 198
                 +  +++    +    V + + +EK G + +T      ++  SG  D   +KEV+
Sbjct: 133 NTSKPVTAKIRLGWDKESVNAVEVSKLIEKAGASGITVHGRTRSEFYSGHADWEKIKEVK 192

Query: 199 EALSVPMVANGGV 211
           EA+++P++ NG V
Sbjct: 193 EAVNIPVIGNGDV 205


>UniRef50_A2EN54 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 321

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 57/210 (27%), Positives = 106/210 (50%), Gaps = 11/210 (5%)

Query: 23  VC-APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQF 81
           VC APMV    + FR L      D+C+T MI    + ++   R  +   +  D P++ Q 
Sbjct: 15  VCLAPMVEMGDIAFRILCHRHGCDVCWTGMINGSQWNRSKTYRQQQIEYSEEDRPLVIQI 74

Query: 82  AANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141
           + +   D +  +K +  +   +D+N GC QK A +  YG  ++   +   ++V  ++++ 
Sbjct: 75  SGSIDVDLLTTAKSMSEFGVPIDINLGCCQKVAKRGEYGYFMVDSEQKRQNVVNLIKSI- 133

Query: 142 PNKFSIS--VKIRLLND------IKKTVILCQQLEKCGVTFLTSMEEHCTKSS-GPVDIN 192
           P++ ++   VKIR L D      I  TV   + LE+ G + +T       +   GP++  
Sbjct: 134 PSEITVPLYVKIRALTDESGIPSIPITVDFAKHLEEAGASLITIHGRSAAQDKHGPLNKE 193

Query: 193 GLKEVREALSVPMVANGGVKHLNDATTYMK 222
            +K V +A+S+P++ NGG+  L+DA   ++
Sbjct: 194 LVKAVVQAVSIPVIVNGGINSLDDARNMIR 223


>UniRef50_Q4PG83 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 527

 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 68/230 (29%), Positives = 110/230 (47%), Gaps = 40/230 (17%)

Query: 22  KVCAPMVRYSKVHFRTLVRNFNADLCFTPMI----LADSFCQNSKARANEF--------- 68
           +V APMV  S++ +R L R + +DL +TPMI     AD   +  K +  E          
Sbjct: 51  RVVAPMVDQSELAWRILSRRYGSDLVYTPMINAKLFADENSKKKKVKYQEVNFNREHAEE 110

Query: 69  ----------------MTTTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQK 112
                            +  TD P+  QF +N+ +  + A+K+V    D VDLN GCPQ 
Sbjct: 111 GASSPIASLLSNEGEGSSKDTDRPLFVQFCSNDPETLLKAAKVVEDRCDAVDLNLGCPQH 170

Query: 113 WAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGV 172
            A +  YG  L+    +I+ ++  L   L  K  ++ K+R+   ++KT+   + LE+ G 
Sbjct: 171 IARRGHYGSYLMEDWSLIFSLINILHVNL--KVPVTAKMRVYESVEKTITYARLLERAGA 228

Query: 173 TFLT------SMEEHCTKSSGPVDINGLKEVREALSVPMVANGGVKHLND 216
             +T      +M+ H T   G  D   ++ V+EA++VP+ ANG V +  D
Sbjct: 229 QIITVHGRTRNMKGHLT---GLADWAKIRAVKEAVNVPVFANGNVLYPQD 275


>UniRef50_A2F0D1 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 333

 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 63/216 (29%), Positives = 100/216 (46%), Gaps = 23/216 (10%)

Query: 26  PMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP--------- 76
           PMVR S + FR +     AD  + P    DS   +      +  T    +P         
Sbjct: 17  PMVRASNLPFRLMCLENGADGVYGPATSVDSILASHYDENEDPYTMYFGWPKNPHVHFHT 76

Query: 77  -------VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129
                  +I Q   N+    V A+ +V  + D +DLNCGCP+ +A   G G SL+S+PEI
Sbjct: 77  DPKEKGKLIFQILTNDASKAVQAASVVVKFADAIDLNCGCPESFATSRGTGSSLMSEPEI 136

Query: 130 IYDIVKGLRNVLPNKFSISVKIRLLNDIKKTV---ILCQQLEKCGVTFLTSMEEHCTKSS 186
           + D+V  LR        ISVK R+ ++I++++   + C+      +     ++E   K+ 
Sbjct: 137 VADVVSALRR--NYNVPISVKHRIHHNIEESIQFAVACENAGASAIAVHGRLKEQ--KNK 192

Query: 187 GPVDINGLKEVREALSVPMVANGGVKHLNDATTYMK 222
           G V  + +K V + L V  + NGGVK+   A   M+
Sbjct: 193 GSVAYDNMKLVFDHLHVAKIGNGGVKNREMAKEMME 228


>UniRef50_A4M5I1 Cluster: Dihydrouridine synthase, DuS; n=1;
           Petrotoga mobilis SJ95|Rep: Dihydrouridine synthase, DuS
           - Petrotoga mobilis SJ95
          Length = 301

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 52/198 (26%), Positives = 92/198 (46%), Gaps = 4/198 (2%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           APM  Y+   FR + R F A   FT MI  DS  + ++ +  + +    +  +  Q   N
Sbjct: 9   APMADYTDYPFREICRRFGAKFTFTEMISVDSIIRENE-KVEKMLPQKGEDNIGVQLFGN 67

Query: 85  NRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNK 144
               F++A+K +      +D+N  CP    +K G G +LL  P+++ DIV  L+  +   
Sbjct: 68  ETTKFIEAAKSIQHLASWIDINAACPVNKVVKKGSGAALLKNPKLLGDIVFNLKKSI--D 125

Query: 145 FSISVKIRLLNDIKKTVILCQQLEKCGVTF-LTSMEEHCTKSSGPVDINGLKEVREALSV 203
             + VK+RL  D      + + +EK G  + +          SG  +   LK+++  +++
Sbjct: 126 LPVGVKVRLGYDQINIEEVAETVEKAGADYIIVHGRTRSQMYSGIANREILKKLKAKITI 185

Query: 204 PMVANGGVKHLNDATTYM 221
           P+ A+G V    D   Y+
Sbjct: 186 PLGASGDVFSKKDIDDYL 203


>UniRef50_Q5KP54 Cluster: TRNA dihydrouridine synthase, putative;
           n=1; Filobasidiella neoformans|Rep: TRNA dihydrouridine
           synthase, putative - Cryptococcus neoformans
           (Filobasidiella neoformans)
          Length = 610

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 49/152 (32%), Positives = 79/152 (51%), Gaps = 5/152 (3%)

Query: 74  DFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDI 133
           D P+I QF AN+ D  + A+K V    D VD+N GCPQ  A +  YG  L  + E+I+ +
Sbjct: 149 DRPLIVQFCANDPDILLAAAKKVEHRCDAVDINFGCPQGIAKRGHYGSFLQDEWELIHKL 208

Query: 134 VKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVD 190
           +  L   L     ++ K R+  D+ KT+   + +E  G   LT      E   +++G  D
Sbjct: 209 ISTLHENL--SVPVTAKFRIFPDLDKTIAYARMMEAAGAQILTCHGRTREMKGQNTGLAD 266

Query: 191 INGLKEVREALSVPMVANGGVKHLNDATTYMK 222
              ++EV++A+ VP+ ANG + +  D    M+
Sbjct: 267 WEYIREVKKAVKVPVFANGNILYREDVDRCME 298


>UniRef50_Q9XWJ9 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 436

 Score = 82.6 bits (195), Expect = 7e-15
 Identities = 59/205 (28%), Positives = 106/205 (51%), Gaps = 20/205 (9%)

Query: 22  KVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTT-----DFP 76
           K+ APMVR  +   R L   + ADLC+T  I+     + ++   NE + T       D  
Sbjct: 9   KILAPMVRAGRTPLRLLCLKYGADLCYTEEIVDKKLIEATRV-VNEALGTIDYRNGDDII 67

Query: 77  V----------IAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSK 126
           +          I Q   N+ +     +++V   V G+D+N GCP+ +++  G G +LL++
Sbjct: 68  LRLAPEEKGRCILQIGTNSGEKAAKIAQIVGDDVAGIDVNMGCPKPFSIHCGMGAALLTQ 127

Query: 127 PEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFL-TSMEEHCTKS 185
            E I DI+  L++    K  ++ KIR+L+D + T+ L Q++EKC V+ L         + 
Sbjct: 128 TEKIVDILTSLKSAA--KVPVTCKIRVLDDPEDTLKLVQEIEKCRVSALGVHGRRRDERQ 185

Query: 186 SGPVDINGLKEVREAL-SVPMVANG 209
                I+ +++V +A+ S+P+++NG
Sbjct: 186 PDKCRIDEIRDVAQAVQSIPVISNG 210


>UniRef50_A2ACC0 Cluster: Novel protein; n=17; Eumetazoa|Rep: Novel
           protein - Mus musculus (Mouse)
          Length = 194

 Score = 82.2 bits (194), Expect = 9e-15
 Identities = 59/188 (31%), Positives = 90/188 (47%), Gaps = 18/188 (9%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           V APMV  S++ +R L R   A LC+TPM+ A  F +++  R            +     
Sbjct: 20  VVAPMVDQSELAWRLLSRRHGAQLCYTPMLHAQVFVRDANYRKEN---------LYCDVC 70

Query: 83  ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
             +R   V A+ L   Y D +DLN GCPQ  A +  YG  L  +    +D+++ +  +  
Sbjct: 71  PEDRPLIVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQEE----WDLLQRMILLAH 126

Query: 143 NKFSISV--KIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVDINGLKEV 197
            + S+ V  KIR+  +I KTV   Q LEK G   LT     +E     +G      +K V
Sbjct: 127 ERLSVPVTCKIRVFPEIDKTVRYAQMLEKAGCQLLTVHGRTKEQKGPMAGTASWEHIKAV 186

Query: 198 REALSVPM 205
           R+A+ +P+
Sbjct: 187 RKAVGIPV 194


>UniRef50_Q4D174 Cluster: Dihydrouridine synthase (Dus), putative;
           n=2; Trypanosoma cruzi|Rep: Dihydrouridine synthase
           (Dus), putative - Trypanosoma cruzi
          Length = 548

 Score = 81.8 bits (193), Expect = 1e-14
 Identities = 66/230 (28%), Positives = 104/230 (45%), Gaps = 33/230 (14%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEF----------MTTT 72
           V  PMV  S++ FR L R + A L ++PM+ A SF Q+++ RA  F          MT T
Sbjct: 99  VVGPMVDQSELPFRMLCRRYGATLAYSPMLHARSFAQSAQYRARYFSTTPHRAELAMTAT 158

Query: 73  -------------------TDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKW 113
                              TD P+  QF  N+ D  + A++ V    + VD+N GCPQ  
Sbjct: 159 ASGEGEAAEDAGRTSDGEETDHPLFVQFCGNDADTLLAAARHVEDDCEAVDVNLGCPQGI 218

Query: 114 AMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVT 173
           A +  YG  L+   + +++I+  L   L  +  ++ K+R+ +D   T+   + L   G+ 
Sbjct: 219 ARRGHYGSFLMEDWDRVHNILHCLAVEL--RVPVTAKMRVFDDDALTLKYAEMLRDTGIA 276

Query: 174 FLTSMEEHCTKSSGPVDINGLKEVREAL--SVPMVANGGVKHLNDATTYM 221
            L           G  D+  ++ VRE L  S+P++ NG V    D    M
Sbjct: 277 VLCVHGRTRHNKRGIADMEKIRRVREHLRGSIPVIGNGNVLTFEDVRRNM 326


>UniRef50_Q7SGX4 Cluster: Putative uncharacterized protein
           NCU03195.1; n=1; Neurospora crassa|Rep: Putative
           uncharacterized protein NCU03195.1 - Neurospora crassa
          Length = 341

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 61/191 (31%), Positives = 90/191 (47%), Gaps = 24/191 (12%)

Query: 49  TPMILADSFCQNSKARANEFMTTTT--DFPVIAQFAANNRDDFVDASKLVYPYVDGVDLN 106
           TP        QN  AR ++   +T     P + QF AN+  +   AS LV PY  GVDLN
Sbjct: 4   TPERSNQDIVQNRFARDSDLTISTNGPQPPTVVQFGANDPQELARASTLVAPYAGGVDLN 63

Query: 107 CGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL---------------PNKFSISVKI 151
           CGCPQ WA  +  G +L+ K E++ D+V   R  L               P   S+SVKI
Sbjct: 64  CGCPQSWACAETLGAALMEKRELVRDMVIETREYLRRDGWGVGKERDVDNPKGRSVSVKI 123

Query: 152 RLLNDIKKTVILCQQL----EKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREAL--SVP 204
           R+  D++KT+     +    +   + +LT       T SS P+++  L+ +       VP
Sbjct: 124 RVHKDLRKTMDFITTVLGPSQDRHIDWLTIHPRTRQTPSSTPINVEALEILTSTFGDKVP 183

Query: 205 MVANGGVKHLN 215
           ++ +G V  LN
Sbjct: 184 ILLSGDVFTLN 194


>UniRef50_Q6AJZ5 Cluster: TRNA-dihydrouridine synthase; n=1;
           Desulfotalea psychrophila|Rep: TRNA-dihydrouridine
           synthase - Desulfotalea psychrophila
          Length = 328

 Score = 80.2 bits (189), Expect = 4e-14
 Identities = 57/205 (27%), Positives = 89/205 (43%), Gaps = 10/205 (4%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           V AP+  Y+ + FR L   F AD   + MI       N +       +   + PV  Q  
Sbjct: 14  VLAPLAGYTDLSFRLLCHQFGADYTVSEMISCHGLFYNQQRTLEMLASLPEERPVSFQLF 73

Query: 83  ANNRDDFVDASKLVYPYV-DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141
               D    A+ ++  +  D +D+N GCP +   K G G +L+S PE+ YD++   R+V+
Sbjct: 74  GAEPDIMAKATLILNDFQPDMIDINMGCPVRKVTKKGAGAALMSTPELAYDVI---RSVV 130

Query: 142 PNKFSISVKIRLLNDIKKT----VILCQQLEKCGVTFL-TSMEEHCTKSSGPVDINGLKE 196
            N   I V ++    +  T    V      E+ G   +           SG  D   +KE
Sbjct: 131 DNT-DIPVTVKFRAGVSSTELNGVEFGLMTERAGAAAVAVHGRTRAQAFSGVADRGIIKE 189

Query: 197 VREALSVPMVANGGVKHLNDATTYM 221
           V+EALS+P++ NG +    D    M
Sbjct: 190 VKEALSIPVIGNGDILSYQDGLDMM 214


>UniRef50_Q4WRF0 Cluster: Dihydrouridine synthase family protein,
           putative; n=9; Pezizomycotina|Rep: Dihydrouridine
           synthase family protein, putative - Aspergillus
           fumigatus (Sartorya fumigata)
          Length = 541

 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 47/145 (32%), Positives = 74/145 (51%), Gaps = 5/145 (3%)

Query: 74  DFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDI 133
           D P+I QF AN+ DDF++A++ V PY D VDLN GCPQ  A K  YG  L    ++IY +
Sbjct: 124 DRPLIVQFCANDPDDFLEAARHVAPYCDAVDLNLGCPQGIARKGHYGAFLQEDWDLIYKL 183

Query: 134 VKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVD 190
           +  L   LP    ++ K R+    +KT+   + +   G + +T      E    ++G  D
Sbjct: 184 INRLHKELP--IPVTAKFRIQESKEKTLEYAKMILSAGASIITLHGRTREQKGHNTGLAD 241

Query: 191 INGLKEVREALSVPMVANGGVKHLN 215
            + ++ +R+ L    V      +LN
Sbjct: 242 WSYIRYLRDNLPPETVIFANGNNLN 266


>UniRef50_Q9NX74 Cluster: tRNA-dihydrouridine synthase 2-like; n=27;
           Eumetazoa|Rep: tRNA-dihydrouridine synthase 2-like -
           Homo sapiens (Human)
          Length = 493

 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 56/206 (27%), Positives = 103/206 (50%), Gaps = 22/206 (10%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP------ 76
           + APMVR   +  R L  ++ AD+ +   ++     Q  K   NE ++T  DF       
Sbjct: 15  ILAPMVRVGTLPMRLLALDYGADIVYCEELIDLKMIQ-CKRVVNEVLSTV-DFVAPDDRV 72

Query: 77  -----------VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLS 125
                      V+ Q   ++ +  +  ++LV   V G+D+N GCP++++ K G G +LLS
Sbjct: 73  VFRTCEREQNRVVFQMGTSDAERALAVARLVENDVAGIDVNMGCPKQYSTKGGMGAALLS 132

Query: 126 KPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFL-TSMEEHCTK 184
            P+ I  I+  L  V   +  ++ KIR+L  ++ T+ L +++E+ G+  +     +   +
Sbjct: 133 DPDKIEKILSTL--VKGTRRPVTCKIRILPSLEDTLSLVKRIERTGIAAIAVHGRKREER 190

Query: 185 SSGPVDINGLKEVREALSVPMVANGG 210
              PV    +K + + LS+P++ANGG
Sbjct: 191 PQHPVSCEVIKAIADTLSIPVIANGG 216


>UniRef50_A2FJB5 Cluster: TIM-barrel protein, nifR3 family protein;
           n=1; Trichomonas vaginalis G3|Rep: TIM-barrel protein,
           nifR3 family protein - Trichomonas vaginalis G3
          Length = 301

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 54/196 (27%), Positives = 96/196 (48%), Gaps = 10/196 (5%)

Query: 27  MVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAANNR 86
           M  Y+ + FR +     AD+  T M+ A +    +K   +    +  +  V  Q   ++ 
Sbjct: 1   MAGYTDIAFREVATEKGADITVTEMVSAMALVYENKKTIDLLDISPKEKKVAVQIFGSDP 60

Query: 87  DDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKF 145
           D   +A++++  Y    VD+N GCP    +K+  G  LLS P ++YDIVK +  V  +  
Sbjct: 61  DVMGEAARILNDYDFSYVDINMGCPAPKIVKNNSGSHLLSNPSLVYDIVKSV--VKNSNK 118

Query: 146 SISVKIRLLNDIKKTVILCQQLEKCGVTFLT----SMEEHCTKSSGPVDINGLKEVREAL 201
            ++ K+R       ++   + +E  G +F+T    + EE+ T   G  D + +KEV+E +
Sbjct: 119 PVTAKVRKGIGGVSSMKAIKNIEAAGASFVTVHGRTREEYYT---GKADWDFIKEVKENV 175

Query: 202 SVPMVANGGVKHLNDA 217
            +P++ NG V    DA
Sbjct: 176 KIPVIGNGDVDSPEDA 191


>UniRef50_Q54QJ2 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 402

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 59/210 (28%), Positives = 106/210 (50%), Gaps = 24/210 (11%)

Query: 22  KVCAPMVRYSKVHFRTLVRNFNADLCFTP-----MILADSFCQNSKARANEFM------- 69
           K+ APMVR      R L  N+  D+ ++       ++  +   N K +  +F+       
Sbjct: 34  KIMAPMVRVGTYPMRILAYNYGCDIAYSEELIDLKLMKSTRVVNEKLKTIDFIAKDQTLC 93

Query: 70  --TTTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKP 127
             T+  D   + Q    +    ++A+K+V   +  +D+N GCP+ ++++ G G +LLSKP
Sbjct: 94  YRTSEKDVRNVLQLGTASSMTALEAAKVVCNDICALDINMGCPKFFSVQGGMGSALLSKP 153

Query: 128 EIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHC----T 183
           E I DI+  L+  L N   I+ KIRLL+  ++T+ L + +E  GV   +++  HC     
Sbjct: 154 ETIKDILTTLKRNL-NGIPITCKIRLLSTDQETIDLLRIIESTGV---SAIGVHCRMIPE 209

Query: 184 KSSGPVDINGLKEV--REALSVPMVANGGV 211
           +   P   + L+ +    + SVP++ANG +
Sbjct: 210 RPRDPAHWDRLENILSNASFSVPIIANGDI 239


>UniRef50_Q5KGP0 Cluster: Putative uncharacterized protein; n=3;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 496

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 65/218 (29%), Positives = 107/218 (49%), Gaps = 26/218 (11%)

Query: 13  DAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSF--CQNS--------- 61
           D +IN     V APMVR   +  R L   + A L ++P ++  +    + S         
Sbjct: 101 DNEINYKNKLVLAPMVRTGSLPMRLLSLYYGAGLVWSPEVVDRAIIGAERSVDPVTGVIT 160

Query: 62  --KARANEFMTTTTDFP-VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDG 118
             K +   F T   + P +I Q  ++N +  V A++ V   V G+DLNCGCP+ ++   G
Sbjct: 161 YHKGQGPIFSTHPAEKPFLIFQIGSSNPELAVKAAQTVQQDVAGIDLNCGCPKPFSTHAG 220

Query: 119 YGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM 178
            G +LLS PE++ DI++ L + +P    IS KIRLL     T+ L  ++ + GV  LT  
Sbjct: 221 MGAALLSTPELLLDILRALLDSIP--LPISCKIRLLPTQPSTLYLASRILRTGVRNLT-- 276

Query: 179 EEHC-TKSSGPVD------INGLKEVREALSVPMVANG 209
             HC T+   P +      ++ + E+ +   + ++ NG
Sbjct: 277 -VHCRTRQMRPGERALWERLSSIVELGKRRGISVICNG 313


>UniRef50_UPI00015B40A4 Cluster: PREDICTED: similar to
           tRNA-dihydrouridine synthase; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to
           tRNA-dihydrouridine synthase - Nasonia vitripennis
          Length = 505

 Score = 77.0 bits (181), Expect = 3e-13
 Identities = 62/218 (28%), Positives = 103/218 (47%), Gaps = 21/218 (9%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTT-----TDFPV 77
           + APMVR   +  R L   + AD+ +T  ++ D     S  R NE + T      TD  +
Sbjct: 60  IMAPMVRIGTLPMRLLALEYGADIVYTEELI-DWKLLRSVRRVNEVLGTVDYIDRTDGTI 118

Query: 78  IAQFAANNRDDFV------DAS------KLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLS 125
           + + +   RD  V      DA+      KLV   V G+D+N GCP+++++  G G +LL 
Sbjct: 119 VFRTSPIERDRVVLQLGTCDANRALKVAKLVEQDVAGIDVNMGCPKRFSILGGMGAALLK 178

Query: 126 KPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHC-TK 184
           +PE   +I++ L   L     ++ KIR+L +++ T+ L   L   G++ +T        +
Sbjct: 179 QPEKASEILRTLVGGL--SIPVTCKIRVLGNVEDTLKLVDTLVDTGISAITVHGRTVDER 236

Query: 185 SSGPVDINGLKEVREALSVPMVANGGVKHLNDATTYMK 222
              P     +K V E   +P++ANGG K +       K
Sbjct: 237 PQHPNRSEFIKRVAEHAKIPVIANGGSKEIEKRADIFK 274


>UniRef50_Q7RX85 Cluster: Putative uncharacterized protein
           NCU00065.1; n=3; Pezizomycotina|Rep: Putative
           uncharacterized protein NCU00065.1 - Neurospora crassa
          Length = 629

 Score = 77.0 bits (181), Expect = 3e-13
 Identities = 70/224 (31%), Positives = 101/224 (45%), Gaps = 37/224 (16%)

Query: 23  VCAPMVRYSKVHFRTLVRNF-NAD-----LCFTPMILADSFCQNSKARANEFMTT----T 72
           + APMV  S+  +R L R+F  AD     LC+TPM  A  F +  K R + F       T
Sbjct: 53  IVAPMVDQSEFAWRMLTRSFLPADEQHKLLCYTPMFHARLFTEAPKYRDSHFQPIRGPLT 112

Query: 73  TDFP--------------------VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQK 112
            D P                    +  QF AN+    + A+KLV PY D VDLN GCPQ 
Sbjct: 113 ADSPRPDSSDYVPFLDGNPEFDRSLFVQFCANDPAYLLSAAKLVAPYCDAVDLNLGCPQG 172

Query: 113 WAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGV 172
            A +  YG  L    E+I++++  L   L     ++ KIR+L+  + T+   Q + + G 
Sbjct: 173 IAKRGQYGSFLQENQELIFELINTLHKEL--DIPVTAKIRILDTKEATLKYAQNVLRAGA 230

Query: 173 TFLT---SMEEHCTKSSGPVDINGLKEVREALSVPMV--ANGGV 211
           + LT      E     +G  D   ++ +RE L    V  ANG +
Sbjct: 231 SILTVHGRRREQKGHQTGLADWEYIRYLRENLPKETVIFANGNI 274


>UniRef50_Q59YG4 Cluster: Potential tRNA dihydrouridine synthase;
           n=2; Saccharomycetales|Rep: Potential tRNA
           dihydrouridine synthase - Candida albicans (Yeast)
          Length = 433

 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 58/179 (32%), Positives = 91/179 (50%), Gaps = 24/179 (13%)

Query: 22  KVC-APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTT--------- 71
           K+C APMVR  ++  R L   +  DL +TP ++     Q+++    E  T          
Sbjct: 7   KLCLAPMVRSGELPIRLLSLRYGCDLLWTPELVDKKILQSTRIINQELNTIDYIVSNHQQ 66

Query: 72  ----TTDF---PV-----IAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGY 119
               T  F   PV     I Q  +++    VDA++ V   VDG+DLNCGCP+ ++   G 
Sbjct: 67  SDKKTVIFRKHPVETGRLILQLGSSDPQLAVDAARKVIDDVDGIDLNCGCPKNFSTHSGM 126

Query: 120 GCSLLSKPEIIYDIVKGL--RNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176
           G  LL  P+ +  I+  L  +  +PNK SIS KIRL N+  ++  L +++ + G++ LT
Sbjct: 127 GAELLKTPDKLCSILINLVEKIGIPNKKSISCKIRLFNNYDQSKNLIEKILQTGISNLT 185


>UniRef50_Q1NXZ7 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3 precursor; n=2; delta proteobacterium MLMS-1|Rep:
           Dihydrouridine synthase TIM-barrel protein nifR3
           precursor - delta proteobacterium MLMS-1
          Length = 313

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 53/203 (26%), Positives = 90/203 (44%), Gaps = 5/203 (2%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           V AP+  YS + FR L R + A LC++ M+      +   A      TT  + P++ Q  
Sbjct: 16  VAAPLAGYSDLPFRLLCREYGAGLCYSEMLSCHGLVRRQPATIEMLATTAAERPLLMQLF 75

Query: 83  ANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141
               +   +A+ ++    +DG+D+N GCP +  +K G G +L+  PE+   I  G     
Sbjct: 76  GAEPEVMGEAAAILSRLPIDGIDINMGCPVRKVVKKGAGAALMRDPELAAAIT-GAVTAA 134

Query: 142 PNKFSISVKIRLLNDIKK--TVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVR 198
                ++VKIR   + K+       + L   G   +T      +   +G  D   +  V+
Sbjct: 135 AGDLPVTVKIRSGWNHKQINAPDFARLLVAHGAAAVTIHARTWSDGFTGRADWAVIAAVK 194

Query: 199 EALSVPMVANGGVKHLNDATTYM 221
            A+SVP++ NG +     A   M
Sbjct: 195 RAVSVPVIGNGDIGSYEQALAMM 217


>UniRef50_Q8RFK3 Cluster: Nitrogen regulation protein NIFR3; n=3;
           Fusobacterium nucleatum|Rep: Nitrogen regulation protein
           NIFR3 - Fusobacterium nucleatum subsp. nucleatum
          Length = 307

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 52/196 (26%), Positives = 96/196 (48%), Gaps = 5/196 (2%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           AP+   +   FR ++ +F  DL FT M+  ++    +    ++ +       V  Q    
Sbjct: 7   APIAGVTDYTFRGILEDFKPDLIFTEMVSVNALSVLNDKTISKILKLREGNAV--QIFGE 64

Query: 85  NRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143
           + +    + K +    V  ++LNCGCP K  +  GYG +L+ +PE I  I+  +++VL N
Sbjct: 65  DIEKIKASVKYIENLGVKHINLNCGCPMKKIVNCGYGAALVKEPEKIKKILSEIKSVLNN 124

Query: 144 KFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHCTK-SSGPVDINGLKEVREAL 201
              +SVKIR+   + +  + + +  E+ G   +T       +  SG  D   +KEV++ +
Sbjct: 125 DTKLSVKIRIGYKEPENYIQIGKIAEELGCDHITVHGRTREQLYSGKADWKYIKEVKDNI 184

Query: 202 SVPMVANGGVKHLNDA 217
           S+P++ NG +    DA
Sbjct: 185 SIPVIGNGDIFTGEDA 200


>UniRef50_Q2H6D9 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 464

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 54/175 (30%), Positives = 82/175 (46%), Gaps = 21/175 (12%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNAD------LCFTPMILADSFCQNSKARANEFMTTTTDF- 75
           + APMV  S+  +R L R+F  +      L ++PM  A  F ++ K R   F  T  D  
Sbjct: 39  IVAPMVDQSEFAWRMLSRSFLPESEQSGLLAYSPMFHARLFSESQKYRDQHFQPTKPDCD 98

Query: 76  ------------PVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSL 123
                       P   QF AN+    ++A+K+  PY D VDLN GCPQ  A K  YG  L
Sbjct: 99  KLYLDGNPAIDRPFFVQFCANDPQALLNAAKIAAPYCDAVDLNLGCPQGIAKKGHYGSFL 158

Query: 124 LSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM 178
               ++I+ ++K L   L     ++ KIR+L   + T+   Q + +   + LT +
Sbjct: 159 QEDQDLIHQLIKILHENL--DIPVTAKIRILETKEATLKYAQNVLRPTASILTCL 211


>UniRef50_Q8KB61 Cluster: TIM-barrel protein, nifR3 family; n=10;
           Chlorobiaceae|Rep: TIM-barrel protein, nifR3 family -
           Chlorobium tepidum
          Length = 352

 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 50/197 (25%), Positives = 85/197 (43%), Gaps = 2/197 (1%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           + APM   +   FR L +   AD+ +T  I A++  +  +    +      + PV  Q  
Sbjct: 18  ILAPMEDVTDRAFRQLCKQHGADIVYTEFISAEALRRGVEKSIRKITVADHERPVAVQIF 77

Query: 83  ANNRDDFVDASKLVYPYV-DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141
            N  +  V+A+ +   Y  D +D+N GCP K     G G +LL +PE + +I   + N +
Sbjct: 78  GNTVESMVEAAAIAETYEPDYLDINFGCPVKKVAGRGAGAALLKEPEKLSEIASAVVNAV 137

Query: 142 PNKFSISVKIRLLNDIKKTVILCQQLEKCGV-TFLTSMEEHCTKSSGPVDINGLKEVREA 200
               +   +I   +D        ++LE  G+               G  D   + E ++A
Sbjct: 138 SLPVTAKTRIGWDHDSINITDTVRRLEDAGIRAVAVHGRTRSDMYKGRADWGRIAEAKQA 197

Query: 201 LSVPMVANGGVKHLNDA 217
            S+P++ANG V    DA
Sbjct: 198 CSIPVIANGDVWLPEDA 214


>UniRef50_Q9VY45 Cluster: CG1434-PA; n=6; Endopterygota|Rep:
           CG1434-PA - Drosophila melanogaster (Fruit fly)
          Length = 473

 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 58/211 (27%), Positives = 101/211 (47%), Gaps = 21/211 (9%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTT-----TDFPV 77
           + APMVR   +  R L     AD+ +T   L D     S  R N  + T      +D  +
Sbjct: 27  ILAPMVRVGTLPMRLLALEMGADIVYTEE-LVDIKLIKSIRRPNPALGTVDFVDPSDGTI 85

Query: 78  IAQFAANNRDDFV------DAS------KLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLS 125
           + +  A      V      DA       KL+   + G+D+N GCP+++++K G G +LL+
Sbjct: 86  VFRTCAQETSRLVLQMGTSDAGRALAVGKLLQRDISGLDINMGCPKEFSIKGGMGAALLA 145

Query: 126 KPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFL-TSMEEHCTK 184
            P+    I++ L + L     ++ KIR+L D++ T+ L Q+L   G+  +         +
Sbjct: 146 DPDKAAHILRTLCSGL--DIPVTCKIRILPDVEGTIDLVQKLAATGIAAIGIHARTRDER 203

Query: 185 SSGPVDINGLKEVREALSVPMVANGGVKHLN 215
              P     L+ V +A+ +P++ANGG K+++
Sbjct: 204 PQHPAHPEVLRAVAQAVDIPIIANGGSKNMH 234


>UniRef50_Q4S086 Cluster: Chromosome undetermined SCAF14784, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF14784,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 505

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 39/99 (39%), Positives = 53/99 (53%), Gaps = 2/99 (2%)

Query: 27  MVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTT--DFPVIAQFAAN 84
           MV  S++ +R L R   A LC+TPM  A  F +++  R +         D P+I QF AN
Sbjct: 1   MVDQSELAWRLLSRRHGAQLCYTPMFHAQVFVRDANYRRDNLYNEVCEEDRPLITQFCAN 60

Query: 85  NRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSL 123
           + + FV A+ L   Y D +DLN GCPQ  A +  YG  L
Sbjct: 61  DPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFL 99



 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 27/75 (36%), Positives = 44/75 (58%), Gaps = 3/75 (4%)

Query: 147 ISVKIRLLNDIKKTVILCQQLEKCGVTFLT---SMEEHCTKSSGPVDINGLKEVREALSV 203
           I+ KIR+  +++KTV   Q LEK G   LT     +E     +G      ++ VR+A+++
Sbjct: 157 ITCKIRVFKEMEKTVRYAQMLEKAGCQLLTVHGRTKEQKGAMTGVASWEHIRAVRQAVNI 216

Query: 204 PMVANGGVKHLNDAT 218
           P+ ANG ++HL+D T
Sbjct: 217 PVFANGNIQHLSDVT 231


>UniRef50_Q6C002 Cluster: Yarrowia lipolytica chromosome F of strain
           CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome F of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 394

 Score = 72.5 bits (170), Expect = 7e-12
 Identities = 46/120 (38%), Positives = 69/120 (57%), Gaps = 3/120 (2%)

Query: 60  NSKARANEFMTTTTDFP-VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDG 118
           N++ +A  F T+  +   +I Q  + N +  V A K+V   V G+DLNCGCP+ ++M  G
Sbjct: 68  NTEKKAIIFRTSEAERDKIIFQVGSANPEIAVAACKMVAKDVAGIDLNCGCPKHFSMHAG 127

Query: 119 YGCSLLSKPEIIYDIVKGLRNVL--PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176
            G +LL  P+ +  I++ L   +  P   SISVKIRLL   +KT+ L  +L + GV  LT
Sbjct: 128 MGAALLKTPDKLVAILEALVKEVGEPFNVSISVKIRLLETEEKTLELVDRLAQTGVKNLT 187


>UniRef50_O74731 Cluster: tRNA dihydrouridine synthase Dus2; n=1;
           Schizosaccharomyces pombe|Rep: tRNA dihydrouridine
           synthase Dus2 - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 479

 Score = 72.5 bits (170), Expect = 7e-12
 Identities = 69/224 (30%), Positives = 107/224 (47%), Gaps = 32/224 (14%)

Query: 22  KVC-APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQ--------NSKARANEFMTTT 72
           KVC APMVR  ++  R L   + A+L + P I+  +           N +    +F+   
Sbjct: 9   KVCLAPMVRIGELPMRLLALRYGANLVWGPEIVDKALLSGTPVERVVNDRINCIDFVKPP 68

Query: 73  TD---FPV--------IAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGC 121
           ++   F V        I Q  + + +  V+A+KLV   V G+DLNCGCP+ +++  G G 
Sbjct: 69  SNKVLFRVHPLEANRLIFQLGSASPELAVEAAKLVANDVAGIDLNCGCPKHFSVHAGMGA 128

Query: 122 SLLSKPEIIYDIVKGLRNVL--PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSME 179
            LL   + +  I+  L N +  P K SIS KIRLL   + T+ L +++   GV  +T   
Sbjct: 129 GLLKNQDRLVSILDALVNEIGKPYKISISCKIRLLETKEDTLKLVERICDTGVRAIT--- 185

Query: 180 EHC----TKSSGPVDINGLKE---VREALSVPMVANGGVKHLND 216
            HC     +++ P D + L E   V     V ++ NG V   ND
Sbjct: 186 VHCRTTPMRNTEPADRSYLSEIVGVCRNKDVSILVNGDVLSYND 229


>UniRef50_A4RL93 Cluster: Putative uncharacterized protein; n=1;
           Magnaporthe grisea|Rep: Putative uncharacterized protein
           - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 313

 Score = 72.5 bits (170), Expect = 7e-12
 Identities = 49/145 (33%), Positives = 71/145 (48%), Gaps = 20/145 (13%)

Query: 76  PVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVK 135
           P I QF AN   +   AS LV P+V GVDLNCGCPQ WA  +  G +L+ + E++ D+V 
Sbjct: 41  PTIVQFGANVPVELARASSLVAPFVAGVDLNCGCPQSWACAETLGAALMERRELVRDMVV 100

Query: 136 GLRNVL---------------PNKFSISVKIRLLNDIKKTVILCQQL----EKCGVTFLT 176
             R+ L               P   S+SVKIR+  D++KT+     +        + FLT
Sbjct: 101 ETRSRLASDGWAVGLERDKNDPKGRSVSVKIRVHKDLRKTMDFIDTVIGDPNARNIDFLT 160

Query: 177 -SMEEHCTKSSGPVDINGLKEVREA 200
                  T S  P+++  L  + E+
Sbjct: 161 IHPRTRATPSREPINVESLSILVES 185


>UniRef50_A6DPY9 Cluster: Putative uncharacterized protein; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Putative
           uncharacterized protein - Lentisphaera araneosa HTCC2155
          Length = 330

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 50/181 (27%), Positives = 84/181 (46%), Gaps = 6/181 (3%)

Query: 45  DLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAANNRDDFVDASKLVYPY-VDGV 103
           DL  T  I   S   + ++   + + +  D P+  Q   NN +   +++KLV     D V
Sbjct: 33  DLLCTEFIRISSHKPSMRSLKKQIVKSG-DIPLSVQIMGNNAELMAESAKLVVDCGADAV 91

Query: 104 DLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVI- 162
           D+N GCP K A+K G G ++L  P++ Y ++  +R  +P   ++S KIR   D K+ V  
Sbjct: 92  DVNMGCPTKRAVKGGVGSAMLKDPKLCYQVLASMREQVP--CALSAKIRAGFDNKEGVFE 149

Query: 163 LCQQLEKCGVTFL-TSMEEHCTKSSGPVDINGLKEVREALSVPMVANGGVKHLNDATTYM 221
           + Q +   G  +L            G  D   +  ++E   +P++ NG V+   DA    
Sbjct: 150 ILQAIVDSGADYLAVHPRRRVDHYEGHSDWRIISALKEKSPIPVIGNGDVRTAADAVRMF 209

Query: 222 K 222
           K
Sbjct: 210 K 210


>UniRef50_Q74EF7 Cluster: Dihydrouridine synthase family protein;
           n=2; Deltaproteobacteria|Rep: Dihydrouridine synthase
           family protein - Geobacter sulfurreducens
          Length = 325

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 44/188 (23%), Positives = 84/188 (44%), Gaps = 1/188 (0%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           + APM   + + FR L R   A LCFT M+  +   +  K       +   D P+  Q  
Sbjct: 17  ILAPMAGITNLPFRLLAREQGAGLCFTEMVSVNGLVREGKKSFELLRSVPGDRPLGIQLF 76

Query: 83  ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
            ++ D     +  V  Y D +D+N GCP K  +  G G +L+ +P+ +  IV+ +R    
Sbjct: 77  GDDPDVMGRVAATVDGYGDLIDINMGCPVKKVVGTGAGSALMREPDKVRAIVRAVRRATR 136

Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREAL 201
              ++ ++     +    + + +  E+ G   +T           G  D   L E+++A+
Sbjct: 137 LPLTVKIRSGWSCEDANFIQIARIAEEEGCNAVTLHPRSRAQMFEGTADWTKLAELKQAV 196

Query: 202 SVPMVANG 209
           ++P++ +G
Sbjct: 197 AIPVIGSG 204


>UniRef50_Q31II6 Cluster: Dihydrouridine synthase; n=1;
           Thiomicrospira crunogena XCL-2|Rep: Dihydrouridine
           synthase - Thiomicrospira crunogena (strain XCL-2)
          Length = 320

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 50/202 (24%), Positives = 90/202 (44%), Gaps = 6/202 (2%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           APM   +   +R + R   A    + M+ +    + S   +      T   P I Q    
Sbjct: 15  APMAGITDRVYRDICRESGASYAVSEMVASKKQLRESAKSSTRHADKTETSPRIVQLLGT 74

Query: 85  NRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143
           + ++ VDA+        D +DLN GCP K       G +L+ +PE + DI K L   +  
Sbjct: 75  HPEELVDAALWQQSQGADIIDLNMGCPAKKVCDVAAGSALMGQPERVADIFKSLTEAI-- 132

Query: 144 KFSISVKIRLLNDIK--KTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREA 200
              ++VKIR   D+     V + +  ++ G+  +T        K +G  + + +K V++A
Sbjct: 133 DLPVTVKIRTGTDVDNINAVEIAKLAQELGLKAITIHGRTRADKFNGQAEYDTIKAVKQA 192

Query: 201 LSVPMVANGGVKHLNDATTYMK 222
           + +P++ANG +    +A   +K
Sbjct: 193 VDIPVIANGDICSPKEAQFVLK 214


>UniRef50_A4XH30 Cluster: Putative TIM-barrel protein, nifR3 family;
           n=1; Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
           Putative TIM-barrel protein, nifR3 family -
           Caldicellulosiruptor saccharolyticus (strain ATCC 43494
           / DSM 8903)
          Length = 328

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 57/201 (28%), Positives = 98/201 (48%), Gaps = 13/201 (6%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIA-QFAA 83
           APM  ++   FR+L   F AD+  T M+ A +    S+ +  E ++ + D  +   Q   
Sbjct: 11  APMAGFTDKVFRSLCSRFGADVTVTEMVSAKAITMGSQ-KTKELISFSEDEKIKGVQIFG 69

Query: 84  NNRDDFVDASKLV---YPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140
           ++     +A K++   + Y D +D+N GCP    +K G G +L+  P +   IV+ +  V
Sbjct: 70  SDPHVMAEAVKIIQDEFEY-DFIDINMGCPVPKVVKSGEGSALMKNPSLAAKIVEEVAKV 128

Query: 141 LPNKFSISVKIRLLND---IKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKE 196
             ++  +SVKIR   D   I      C  +++ G +F+T      T+  SG  D   +K 
Sbjct: 129 --SRKPVSVKIRKGFDEENINAPEFAC-IMQESGASFITVHGRTRTQMYSGKADWEIIKM 185

Query: 197 VREALSVPMVANGGVKHLNDA 217
           V+E + +P+VANG +     A
Sbjct: 186 VKEKVKIPVVANGDIVDFESA 206


>UniRef50_A5DYF6 Cluster: Putative uncharacterized protein; n=1;
           Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
           uncharacterized protein - Lodderomyces elongisporus
           (Yeast) (Saccharomyces elongisporus)
          Length = 504

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 59/193 (30%), Positives = 91/193 (47%), Gaps = 30/193 (15%)

Query: 14  AKINKTYL-KVC-APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQN----------- 60
           +K+  TY  KVC APMVR  ++  R L   +  DL ++P  +     Q            
Sbjct: 3   SKMALTYTNKVCLAPMVRSGELPIRLLALRYGCDLVWSPEYIDRKIIQTQRRVNAELNTI 62

Query: 61  ----------SKARANEFMTTTTDFP-----VIAQFAANNRDDFVDASKLVYPYVDGVDL 105
                     SK + N+        P     +I Q   +  +  V+A+  V   VDG+DL
Sbjct: 63  DYIIPNNKDPSKMKHNQDNVVFRKHPEETGKLIFQLGTSTPELAVEAALRVIEDVDGIDL 122

Query: 106 NCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL--PNKFSISVKIRLLNDIKKTVIL 163
           NCGCP+ ++   G G  LL  P+I+  I++ L   +  PNK  IS KIRLL + + + +L
Sbjct: 123 NCGCPKSFSTHGGMGAELLKTPDILCSILRALVEKVGNPNKKPISCKIRLLPNFEASKLL 182

Query: 164 CQQLEKCGVTFLT 176
            +Q+ + G+  LT
Sbjct: 183 IEQICQTGIRNLT 195


>UniRef50_A1SX05 Cluster: Dihydrouridine synthase, DuS; n=3;
           Alteromonadales|Rep: Dihydrouridine synthase, DuS -
           Psychromonas ingrahamii (strain 37)
          Length = 314

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 49/157 (31%), Positives = 78/157 (49%), Gaps = 7/157 (4%)

Query: 71  TTTDFPVIAQFAANNRDDFVD-ASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129
           T +  PV  Q    N     + A + +    DG+DLN GCP K   K+  G  LL  PE 
Sbjct: 59  TASGTPVRIQLLGQNPQCLAENAHQAISIGSDGIDLNFGCPAKTVNKNKGGAVLLKSPEA 118

Query: 130 IYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVI-LCQQLEKCGVTFLTSMEEHCTKSSG- 187
           +Y IV  +R  +P   ++SVKIRL  + K   I   Q ++  G   L       TK+ G 
Sbjct: 119 LYQIVTEVRKAVPVFQTLSVKIRLGYEDKSLAIENAQAIQAAGADELAVHAR--TKAEGY 176

Query: 188 --PVDINGLKEVREALSVPMVANGGVKHLNDATTYMK 222
             P   + + ++++A+++P+ ANG +  ++DA   M+
Sbjct: 177 RPPAHWHWIAKIKDAITIPVTANGDIFSVDDAKRCME 213


>UniRef50_Q550J6 Cluster: Putative uncharacterized protein; n=2;
           Dictyostelium discoideum|Rep: Putative uncharacterized
           protein - Dictyostelium discoideum AX4
          Length = 392

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 42/144 (29%), Positives = 76/144 (52%), Gaps = 6/144 (4%)

Query: 15  KINKTYLKVCAPMVRYSKVHFRTLVRNF--NADLCFTPMILADSFCQNSKARANEFMTTT 72
           K++K    + APM   + + FR L+ N     ++ F   + AD   +N +A  ++   +T
Sbjct: 7   KLSKPIFSL-APMADVTDISFRFLLANCMGKPNVIFNEFVSADGLARNREALIDKLGYST 65

Query: 73  TDFPVIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAM--KDGYGCSLLSKPEI 129
            + P++AQF  N  + F +++K+      DGVD+N GCP +  +  K   G +L++ P +
Sbjct: 66  QEKPIVAQFFGNKPEYFYESAKIANELGYDGVDINMGCPSRKVLSPKQASGAALITNPSL 125

Query: 130 IYDIVKGLRNVLPNKFSISVKIRL 153
             +IVK  +  L  +  +SVK R+
Sbjct: 126 AKEIVKITKEALNFEKPVSVKTRI 149


>UniRef50_Q4PIC3 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 364

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 63/208 (30%), Positives = 92/208 (44%), Gaps = 26/208 (12%)

Query: 18  KTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILA-----DSFCQNSKARANEFMTTT 72
           ++ L   APMV  S + FR       A L +T M LA     D +   S  ++ E  +  
Sbjct: 10  ESLLYCAAPMVGQSDLAFRLQTVQNGATLTWTQMYLAPELSSDQYMLESLLKSLEMGSNA 69

Query: 73  T--------------DFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDG 118
           T                P + Q A NN    V+A++ V PY D +DLN GCPQ+ A +  
Sbjct: 70  TKNMARYRASPLHDQSAPQVVQLAGNNVQQLVEAARRVAPYADAIDLNLGCPQRHAEQGH 129

Query: 119 YGCSLLSKPE--IIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176
           YG  LL K    ++ +IV G+  V      I+ KIRL    ++T  L   L   G + +T
Sbjct: 130 YGACLLPKQNWPLVAEIVSGM--VQAVDVPITTKIRLPVPKEQTAQLAVMLAHAGSSLVT 187

Query: 177 ---SMEEHCTKSSGPVDINGLKEVREAL 201
                     +  G  D++ + +VREAL
Sbjct: 188 VHPRFASSARRRKGLADLDQVVKVREAL 215


>UniRef50_Q7MXX6 Cluster: TIM-barrel protein, putative, NifR3
           family; n=23; Bacteroidetes/Chlorobi group|Rep:
           TIM-barrel protein, putative, NifR3 family -
           Porphyromonas gingivalis (Bacteroides gingivalis)
          Length = 333

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 53/193 (27%), Positives = 88/193 (45%), Gaps = 8/193 (4%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           APM   + V FR + + F ADL ++  + AD+  +       +     ++ P+  Q    
Sbjct: 16  APMEDVTDVAFRIMCKQFGADLVYSEFLSADALIRQVAGTFRKMAIDESERPMAVQIYGR 75

Query: 85  NRDDFVDASKLVYPYVDG-VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143
           +    V+A++L        +DLN GCP K     G G  +L    ++ +I + +  V   
Sbjct: 76  DVASMVEAARLCESAGPNLIDLNFGCPVKRVAGKGAGSGMLRNIPLMIEITREV--VKAV 133

Query: 144 KFSISVKIRL--LNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE- 199
           K  ++VK RL   ND K  V L +QL+ CG+  LT          +G  D   + EV+  
Sbjct: 134 KLPVTVKTRLGWDNDSKIIVDLAEQLQDCGIAALTIHGRTRAQMYTGTADWTLIGEVKNN 193

Query: 200 -ALSVPMVANGGV 211
             + +P++ NG V
Sbjct: 194 PRMQIPIIGNGDV 206


>UniRef50_Q6BX60 Cluster: Debaryomyces hansenii chromosome B of
           strain CBS767 of Debaryomyces hansenii; n=1;
           Debaryomyces hansenii|Rep: Debaryomyces hansenii
           chromosome B of strain CBS767 of Debaryomyces hansenii -
           Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
          Length = 374

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 53/172 (30%), Positives = 90/172 (52%), Gaps = 20/172 (11%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSF--CQ---NSKARANEFMTTTTD----- 74
           APMVR  ++  R +   + ADL +TP I+      C+   N      +F+          
Sbjct: 11  APMVRSGEIPTRLMALRYGADLVWTPEIVDKKLIKCERVINDDLGTVDFLDPNKKVVFRT 70

Query: 75  FP------VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPE 128
           +P      +I Q  + + +  V A+K+V   VDG+DLNCGCP+ ++   G G +LL+ P+
Sbjct: 71  YPAEELGKLIFQIGSADPELAVQAAKIVAQDVDGIDLNCGCPKPFSTHSGMGAALLTTPD 130

Query: 129 IIYDIVKGLRNVLPNKFS--ISVKIRLLN--DIKKTVILCQQLEKCGVTFLT 176
           ++  I++ L + +   +   IS KIRLL+  D+  ++ L  +L K G++ LT
Sbjct: 131 LLELILRNLVSEVGKVYDIPISAKIRLLDDTDVTPSLELIDRLCKTGISNLT 182


>UniRef50_O67533 Cluster: Probable tRNA-dihydrouridine synthase;
           n=1; Aquifex aeolicus|Rep: Probable tRNA-dihydrouridine
           synthase - Aquifex aeolicus
          Length = 316

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 51/198 (25%), Positives = 92/198 (46%), Gaps = 5/198 (2%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           + APM  Y+   FR L R   AD  +T +I A    +N       + T   + P+  Q  
Sbjct: 9   ILAPMASYTHSAFRRLCRRLGADRTYTELISAVGVLRNGIPMKLAYFTEE-ERPIHIQVF 67

Query: 83  ANNRDDFVDASKLVYPYV--DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140
            +N ++   AS ++   +  D +D+N GC     +++     +L  P ++ ++VK     
Sbjct: 68  GSNPEEIAQASVVIAKELKPDFIDINFGCSVPKVLRNKAAGYMLQCPPLMGEVVKETVEA 127

Query: 141 L-PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVR 198
           L P    +S KIRL  +  +   + ++L+K GV+ +        +  SG    + +KE +
Sbjct: 128 LKPYGIPVSAKIRLGFEKDEVERIVEELQKAGVSLIAIHARTAKQGFSGKALWHRIKEAK 187

Query: 199 EALSVPMVANGGVKHLND 216
           +  SVP++ +G VK   D
Sbjct: 188 KVASVPIIGSGDVKSWRD 205


>UniRef50_Q899H0 Cluster: Nitrogen regulation protein nifR3; n=24;
           Clostridia|Rep: Nitrogen regulation protein nifR3 -
           Clostridium tetani
          Length = 322

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 50/210 (23%), Positives = 92/210 (43%), Gaps = 7/210 (3%)

Query: 15  KINKTYLK---VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTT 71
           KI++  LK     AP+   + + FR L +     L +T M+ A +   +S    +    +
Sbjct: 2   KISRLELKGNVFLAPLAGVTDLAFRGLCKRMGCTLVYTEMVSAKALFYDSDKTKDMLRFS 61

Query: 72  TTDFPVIAQFAANNRDDFVDASKLVYPYVDGV---DLNCGCPQKWAMKDGYGCSLLSKPE 128
             + P+  Q      D   +  +  +   D V   D+N GCP    +K+G G +L+  P+
Sbjct: 62  KEELPIAVQIFGKEPDIMANVVEKYFNSNDNVCLIDINMGCPAPKIVKNGEGSALMKNPK 121

Query: 129 IIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SG 187
           +  DIV+ ++ V     ++  +    ND    +   + +E  G   LT       +   G
Sbjct: 122 LASDIVESIKKVSTKPVTVKFRKGFDNDNINALEFAKIMENSGADALTIHGRTREQMYQG 181

Query: 188 PVDINGLKEVREALSVPMVANGGVKHLNDA 217
             D   +K+V+E++ +P++ NG V    DA
Sbjct: 182 KADWEIIKKVKESVKIPVIGNGDVFTGEDA 211


>UniRef50_Q47C15 Cluster: Dihydrouridine synthase, DuS; n=2;
           Betaproteobacteria|Rep: Dihydrouridine synthase, DuS -
           Dechloromonas aromatica (strain RCB)
          Length = 319

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 46/151 (30%), Positives = 77/151 (50%), Gaps = 7/151 (4%)

Query: 71  TTTDFPVIAQFAANNRDDFVD-ASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129
           T T  P+  Q   ++     + A +LV     GVDLN GCP     +   G +LL +PE+
Sbjct: 60  TRTGTPMRVQLLGSDPHFMAENARRLVALNPAGVDLNFGCPAPTVFRHRGGSALLGEPEL 119

Query: 130 IYDIVKGLRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSG- 187
           + +I   +R+V+P     + K+RL ++D  + +   Q LE  G+  L  +    T+S G 
Sbjct: 120 LNEITSAVRSVVPAHIPFTAKMRLGIDDTSRAIDCAQALEAAGINEL--IVHGRTRSDGY 177

Query: 188 --PVDINGLKEVREALSVPMVANGGVKHLND 216
             P     + +VR+A+ +P++ANG V  + D
Sbjct: 178 RPPARWEWIDKVRDAIHIPLIANGEVWTVED 208


>UniRef50_Q1IVR5 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=2; Acidobacteria|Rep: Dihydrouridine synthase
           TIM-barrel protein nifR3 - Acidobacteria bacterium
           (strain Ellin345)
          Length = 370

 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 56/202 (27%), Positives = 93/202 (46%), Gaps = 10/202 (4%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQNSKARANEFMTTT-TDFPVIAQ 80
           V APM   +   FR  +RN     L  T    AD   +  +A+A  ++T    + P+ AQ
Sbjct: 35  VLAPMAGVTDTVFRRFIRNLGGCGLMMTEFTSADGLARMREAKARRYLTFYGNERPISAQ 94

Query: 81  FAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139
              ++ +   DA+K+V     D VDLN GCP K  +K   G  LL     I  I + +R 
Sbjct: 95  LFGSDAETLADAAKVVQDLGFDLVDLNLGCPSKRVVKCNGGSGLLRDLPQIKVIFESVRK 154

Query: 140 VLPNKFSISVKIRLLNDIKKTVI--LCQQLEKCGVTFLTSMEEHCTKS--SGPVDINGLK 195
            +   F  +VK R   + K+ V   L +  E CG+    +M     +   SG  +   + 
Sbjct: 155 AVTIPF--TVKFRAGWNEKELVFLELAKLAENCGLN-AVAMHARTREQGYSGQANWGWIA 211

Query: 196 EVREALSVPMVANGGVKHLNDA 217
           ++++ + +P++ NG ++   DA
Sbjct: 212 DLKQVVKIPVIGNGDIRTPEDA 233


>UniRef50_A6BZR9 Cluster: Predicted TIM-barrel enzyme, possibly
           dehydrogenase, nifR3 family protein; n=1; Planctomyces
           maris DSM 8797|Rep: Predicted TIM-barrel enzyme,
           possibly dehydrogenase, nifR3 family protein -
           Planctomyces maris DSM 8797
          Length = 355

 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 47/197 (23%), Positives = 89/197 (45%), Gaps = 4/197 (2%)

Query: 25  APMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           AP+  Y++  FR  +R      LC T ++LA      S+       T+  D P+  Q   
Sbjct: 28  APLAGYTQHAFRVAIRELGGVGLCTTDLVLASHLLSGSRKSKALLTTSPADRPLTIQIFG 87

Query: 84  NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
               + V A++ +  +    VDLN GCP      +G G  ++  P+    +V  + + + 
Sbjct: 88  GITAELVAAARWLEQHGYAAVDLNMGCPMAKINGNGGGARIMCAPDAACQLVAEVVDAVS 147

Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVREAL 201
              ++ +++    D     +L ++ E+ GV  +T       +   G VD+ G+++  EA+
Sbjct: 148 IPVTVKMRLGWDRDSITAPLLAREFEQAGVAAITVHGRTRNQGFGGTVDLQGIRQTVEAV 207

Query: 202 -SVPMVANGGVKHLNDA 217
             +P++ NG V  + DA
Sbjct: 208 QQIPVIGNGDVCTVEDA 224


>UniRef50_A6CBK4 Cluster: Predicted TIM-barrel enzyme, possibly
           dehydrogenase, nifR3 family protein; n=1; Planctomyces
           maris DSM 8797|Rep: Predicted TIM-barrel enzyme,
           possibly dehydrogenase, nifR3 family protein -
           Planctomyces maris DSM 8797
          Length = 365

 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 53/204 (25%), Positives = 95/204 (46%), Gaps = 8/204 (3%)

Query: 25  APMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           +P+  Y+ + FR +VR      L  T ++ A    + S+       T   D P   Q   
Sbjct: 33  SPLAGYTNLPFRRIVRELGGVGLATTDLVNARGLLEGSEKTLQLTQTCPEDSPFAVQIFG 92

Query: 84  NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
           +      DA++L+    V  +D+N GCP    +K G G S++ +P     +V+ +   + 
Sbjct: 93  SEPQQMKDAAQLLESRGVHSIDINMGCPVNRIVKGGAGASMMCRPSDTVSLVQTVVEAV- 151

Query: 143 NKFSISVKIRLLNDIKK--TVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVRE 199
            K  +SVK+RL  D  +       ++ EK GV  +        +   G V+ +G++ V E
Sbjct: 152 -KIPVSVKMRLGWDDSELSAPFFSREFEKVGVVAVAIHGRTREQGFRGVVNHDGIRRVVE 210

Query: 200 AL-SVPMVANGGVKHLNDATTYMK 222
           A+ S+P++ NG V ++ +A   +K
Sbjct: 211 AVDSIPVIGNGDVTNVAEADFMLK 234


>UniRef50_Q6SFW7 Cluster: NifR3/Smm1 family protein; n=1; uncultured
           bacterium 578|Rep: NifR3/Smm1 family protein -
           uncultured bacterium 578
          Length = 322

 Score = 68.9 bits (161), Expect = 9e-11
 Identities = 41/189 (21%), Positives = 84/189 (44%), Gaps = 2/189 (1%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           APM   S   FR + R   A L  + M++      N+    +     +   P+  Q A +
Sbjct: 15  APMAGTSDKPFRMICREQGAALTTSEMVVMQKHLLNTNKSKHRLDFRSEQSPISIQIAGS 74

Query: 85  NRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143
              +  +++K    +  D +D+N GCP K       G +L+   +++ DI+K + N +  
Sbjct: 75  ESQELAESAKQALEFGADIIDINMGCPAKKVCNKAAGSALMKNEKLVEDIIKAVVNAVNI 134

Query: 144 KFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREALS 202
             ++ ++     + K    + +  E  G+  L         K +G  + + +K+++  +S
Sbjct: 135 PVTLKMRTGWNEENKNAPTIAKIAEDNGIKMLAIHGRTRAQKYNGDAEYDTVKKIKGIVS 194

Query: 203 VPMVANGGV 211
           +P+VANG +
Sbjct: 195 IPVVANGDI 203


>UniRef50_Q0YFW9 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=8; Desulfuromonadales|Rep: Dihydrouridine
           synthase TIM-barrel protein nifR3 - Geobacter sp. FRC-32
          Length = 343

 Score = 68.9 bits (161), Expect = 9e-11
 Identities = 49/192 (25%), Positives = 88/192 (45%), Gaps = 5/192 (2%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           + APM   + +  R L R   A L FT MI  +   +  K   +       D P+  Q  
Sbjct: 34  ILAPMAGLTNLPMRILARECGAALTFTEMISVNGLVREGKKTFDLLRRDPMDRPMGIQIF 93

Query: 83  ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
            ++     + ++LV  Y + +D+N GCP +  +  G G +LL +P  +  I+K +R    
Sbjct: 94  GDDPQLLAEGARLVEQYGELIDINMGCPVRKVVGSGAGSALLREPAKVGMIIKAVRKA-- 151

Query: 143 NKFSISVKIRL-LNDIKKTVILCQQL-EKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE 199
               +++KIR        T +   ++ E  GV  +T           G  D + ++E++E
Sbjct: 152 TSLPLTIKIRTGWGAADHTFLEIGRIAEAEGVDGVTLHPRSRAQMFEGHADWSRIRELKE 211

Query: 200 ALSVPMVANGGV 211
           ALS+P++ +G +
Sbjct: 212 ALSIPVIGSGDI 223


>UniRef50_A2DYY3 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 313

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 52/212 (24%), Positives = 100/212 (47%), Gaps = 21/212 (9%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANE--------------- 67
           + APMVR S + FR     + ADL F+P ++  +   ++  + +                
Sbjct: 14  IAAPMVRGSSLSFRLACLEYGADLVFSPGLVDLAIIGSTMEKDDNNISLIKVENGHNRRI 73

Query: 68  FMTTTTDF-PVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSK 126
           F TT  +   +I Q    +  + + A+ +   +  G+D+NCGCP+ +A   G G  +  +
Sbjct: 74  FHTTAEERGKLIIQLITVDGPNAIKAADMCTEFASGIDINCGCPESFACHRGGGSKM--Q 131

Query: 127 PEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEE-HCTKS 185
            E   D+VK L+  + +   ISVK+R+ + +++++   + +   G   +T        K 
Sbjct: 132 LESAVDVVKTLK--MNSPLPISVKMRVKDTVEESLQFAKAMVDAGAVAITVHGRLAADKR 189

Query: 186 SGPVDINGLKEVREALSVPMVANGGVKHLNDA 217
            G VD   +KE+ + ++   + NGG+ +  DA
Sbjct: 190 HGSVDYEHMKEIFDNINCAKIGNGGICNKADA 221


>UniRef50_Q5ZRM0 Cluster: Nitrogen regulation protein; n=4;
           Legionella pneumophila|Rep: Nitrogen regulation protein
           - Legionella pneumophila subsp. pneumophila (strain
           Philadelphia 1 /ATCC 33152 / DSM 7513)
          Length = 329

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 46/192 (23%), Positives = 88/192 (45%), Gaps = 6/192 (3%)

Query: 26  PMVRYSKVHFRTLVRNFNADL-CFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           P+  YS   FR L   +     C + M  A        +++       T+  +  Q + N
Sbjct: 25  PLAGYSCAPFRDLFNIYTPPAYCVSEMCSAIDILHKHSSQSRYIYRAPTEKFLAYQISGN 84

Query: 85  NRDDFVDAS-KLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143
                 +A+ KL     D +D+NCGCP+    K G G +LL  P+ +  I+  +R  +  
Sbjct: 85  EPHVLAEAAAKLQSLGADLIDINCGCPKSKIRKKGAGSALLEDPQKLIAIISRVRAAI-- 142

Query: 144 KFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSG-PVDINGLKEVREALS 202
              +++KIR+ N+ +K + L +Q+E  G   L       T+    P +   +  ++ A++
Sbjct: 143 SIPLTIKIRIQNN-EKDLTLAKQIEDAGAHALIVHGRRWTEDYDIPCNWQQIANIKNAVN 201

Query: 203 VPMVANGGVKHL 214
           +P++ NG + ++
Sbjct: 202 IPVIVNGDINNI 213


>UniRef50_Q0FAI7 Cluster: tRNA-dihydrouridine synthase, putative;
           n=1; alpha proteobacterium HTCC2255|Rep:
           tRNA-dihydrouridine synthase, putative - alpha
           proteobacterium HTCC2255
          Length = 324

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 46/201 (22%), Positives = 91/201 (45%), Gaps = 4/201 (1%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSK-ARANEFMTTTTDFPVIAQFAA 83
           +P+   + + +R LV +F A L  + M+ +    Q  K ARA   +    +   + Q A 
Sbjct: 14  SPLAGITDLPYRNLVSSFGAGLVVSEMVASHEIMQKGKDARARAELGFNVEGTSV-QIAG 72

Query: 84  NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
            +     + +KL+       +D+N GCP K  +    G +L+  P++   +++ + N + 
Sbjct: 73  RDAFWMSECAKLIEGNGAKIIDINMGCPAKSVVNGASGSALMRTPDLALKLIEAVVNAVD 132

Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREAL 201
              ++  ++   ++      L    EK G+  +T      C    G  D   ++EV+EA+
Sbjct: 133 IPVTLKTRLGWDHNDLNAADLSSSAEKIGIQMITIHGRTRCQFYKGDADWRKIREVKEAV 192

Query: 202 SVPMVANGGVKHLNDATTYMK 222
           ++P++ANG +     A   MK
Sbjct: 193 NIPVIANGDIIDTPTAKLAMK 213


>UniRef50_Q14SX5 Cluster: Putative dihydrouridine synthase; n=1;
           Ruminococcus flavefaciens|Rep: Putative dihydrouridine
           synthase - Ruminococcus flavefaciens
          Length = 332

 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 49/191 (25%), Positives = 84/191 (43%), Gaps = 5/191 (2%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           APM   +   +R + + + A    + M+ A   C + +  A     T  + P+  Q   +
Sbjct: 19  APMAGVADRAYRLMCKRYGAAYVVSEMVSAKGICYSDRKTAELCTVTEEERPMAVQLFGS 78

Query: 85  NRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143
             D   +A K+V  Y  D +D+N GCP    +  G G +L+  P +   I +       +
Sbjct: 79  EPDFMAEAVKIVLDYRPDIIDINMGCPVPKVVGTGAGSALMKDPALAAAITEAAVKAAGD 138

Query: 144 KFSISVKIRL--LNDIKKTVILCQQLEKCGVTFLTSM-EEHCTKSSGPVDINGLKEVREA 200
              ++VKIR    +D      + + LE  G   +           SG  D+N +K V+EA
Sbjct: 139 T-PVTVKIRSGWSSDSINAPEMARALEASGTAAIAVHGRTRDMFYSGQSDMNVIKAVKEA 197

Query: 201 LSVPMVANGGV 211
           +SVP++ NG +
Sbjct: 198 VSVPVIGNGDI 208


>UniRef50_Q5M689 Cluster: Possible transcriptional regulator; n=20;
           Streptococcus|Rep: Possible transcriptional regulator -
           Streptococcus thermophilus (strain ATCC BAA-250 / LMG
           18311)
          Length = 350

 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 55/201 (27%), Positives = 90/201 (44%), Gaps = 9/201 (4%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           V APM   +   FRT+ + F+A L    MI       N++   +       + P+  Q  
Sbjct: 45  VLAPMAGVTNSAFRTIAKEFSAGLVVMEMISEKGLLYNNEKTLHMLHIDENEHPMSIQLF 104

Query: 83  ANNRDDFVDASKLVYPYV--DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140
             + +    A+  +      D VD+N GCP    +K+  G   L  P+ IY IVK + +V
Sbjct: 105 GGDAEGLKRAADFIQTNTKADIVDINMGCPVNKVVKNEAGAKWLKDPDKIYHIVKEVTSV 164

Query: 141 LPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS--SGPVDINGLKEV 197
           L     ++VK+R   +D    V      E  GV+ L +M     +   +G  D   L  V
Sbjct: 165 L--DIPLTVKMRTGWSDSDLAVENALAAESAGVSAL-AMHGRTREQMYTGHCDHETLARV 221

Query: 198 REALS-VPMVANGGVKHLNDA 217
            +A++ +P + NG V+++ DA
Sbjct: 222 AKAITKIPFIGNGDVRNVQDA 242


>UniRef50_A0LJ96 Cluster: Putative TIM-barrel protein, nifR3 family;
           n=1; Syntrophobacter fumaroxidans MPOB|Rep: Putative
           TIM-barrel protein, nifR3 family - Syntrophobacter
           fumaroxidans (strain DSM 10017 / MPOB)
          Length = 352

 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 46/192 (23%), Positives = 87/192 (45%), Gaps = 3/192 (1%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTT-TTDFPVIAQF 81
           V APM   +   +R L+ +F A +  T M+      +N +A  +          P+  Q 
Sbjct: 25  VLAPMAGVTDSAYRALMADFGAAMVTTEMVSIQGLVRNQRATLDLCRQQHPVGVPLAVQV 84

Query: 82  AANNRDDFVDASKLVYPYVDG-VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140
              +     +A++LV       +D+N GCP +  ++ G G  LL  P+ +  +V+ ++  
Sbjct: 85  FGRDPAVMAEAARLVEQGGAALIDINAGCPVRKVVRQGAGAILLKDPDRLAAMVEAVKRA 144

Query: 141 LPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVRE 199
           +    ++ +++   N       L +QL   GV  +T       +  SG  D + + EV+ 
Sbjct: 145 VSVPVTVKIRVGWDNAANGVAGLARQLVSAGVDAITVHGRTAAQMYSGRADWSRIAEVKA 204

Query: 200 ALSVPMVANGGV 211
           A++VP++ NG V
Sbjct: 205 AVAVPVIGNGDV 216


>UniRef50_Q64MI4 Cluster: Putative TIM-barrel enzyme; n=3;
           Bacteroidales|Rep: Putative TIM-barrel enzyme -
           Bacteroides fragilis
          Length = 324

 Score = 66.1 bits (154), Expect = 7e-10
 Identities = 48/193 (24%), Positives = 87/193 (45%), Gaps = 8/193 (4%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           APM   +   FR + + F AD+ +T  + +D+  ++      +      + PV  Q    
Sbjct: 16  APMEDVTDPAFRLMCKKFGADMVYTEFVSSDALIRSVNKTTQKLTICDEERPVAIQIYGK 75

Query: 85  NRDDFVDASKLVYP-YVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143
           + +  V A+++V     D +D+N GCP K     G G  +L     + +I + + + +  
Sbjct: 76  DTEAMVGAARIVEEAQPDILDINFGCPVKKVAGKGAGAGMLQNIPKMLEITRAVVDAV-- 133

Query: 144 KFSISVKIRLLNDIKKTVI--LCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE- 199
           K  ++VK RL  D    +I  L +QL+ CG+  L           +G  D   + EV+  
Sbjct: 134 KIPVTVKTRLGWDADHKIIVDLAEQLQDCGIAALAIHGRTRAQMYTGEADWTLIGEVKNN 193

Query: 200 -ALSVPMVANGGV 211
             + +P++ NG V
Sbjct: 194 PRMHIPIIGNGDV 206


>UniRef50_Q6MNE4 Cluster: Dihydrouridine synthase family protein;
           n=1; Bdellovibrio bacteriovorus|Rep: Dihydrouridine
           synthase family protein - Bdellovibrio bacteriovorus
          Length = 323

 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 44/147 (29%), Positives = 75/147 (51%), Gaps = 9/147 (6%)

Query: 76  PVIAQFAANNRDDF-VDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134
           PV  Q      +   ++A + V     GVDLN GCP K   +   G SLL   + +++IV
Sbjct: 64  PVFVQLLGGQAEPLALNAQRAVKLGALGVDLNFGCPAKTVNRHDGGASLLKSCDRVFNIV 123

Query: 135 KGLRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHC-TKSSG---PV 189
             +R  +P    ++ KIRL  +D  K + + Q +E+   T+LT    HC TK+ G   P 
Sbjct: 124 DTVRKAVPADVPVTAKIRLGFDDPTKCLEIAQAVEEANATWLT---VHCRTKTDGYKPPA 180

Query: 190 DINGLKEVREALSVPMVANGGVKHLND 216
             + + +++E   + ++ANG + ++ D
Sbjct: 181 YWDWIPKIKEKTKIKLIANGEIWNVAD 207


>UniRef50_Q0B0N8 Cluster: Putative TIM-barrel protein, NifR3 family;
           n=2; Clostridiales|Rep: Putative TIM-barrel protein,
           NifR3 family - Syntrophomonas wolfei subsp. wolfei
           (strain Goettingen)
          Length = 318

 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 55/202 (27%), Positives = 98/202 (48%), Gaps = 9/202 (4%)

Query: 22  KVCA-PMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDF-PVIA 79
           +VCA PM   S   +R L R+F   L  + M+ +D      + R ++   ++ +  PV  
Sbjct: 12  RVCAAPMAGVSDKAYRVLARDFGCGLVCSEMV-SDKGLVYGQGRTSKIADSSGEKRPVAV 70

Query: 80  QFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLR 138
           Q   +  +    A+++V     D +D+N GCP    +K+G G +L+        IV+ + 
Sbjct: 71  QIFGSEAESMATAARIVEEMGADIIDINMGCPTPKIVKNGEGAALMLDITKSRGIVREVL 130

Query: 139 NVLPNKFSISVKIRLLNDIKKT--VILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLK 195
            V+  K  ++VK+R   D      + L Q+LE+ GV  +        +  SG  D N +K
Sbjct: 131 RVV--KVPVTVKMRKGWDENSINCLELAQKLEEEGVAAICLHPRSRQQFFSGSADWNLIK 188

Query: 196 EVREALSVPMVANGGVKHLNDA 217
           E+++ L +P++ NG +   +DA
Sbjct: 189 EMKKELKIPVIGNGDIWSADDA 210


>UniRef50_Q9JUP6 Cluster: tRNA-dihydrouridine synthase C; n=4;
           Neisseria|Rep: tRNA-dihydrouridine synthase C -
           Neisseria meningitidis serogroup A
          Length = 333

 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 46/151 (30%), Positives = 74/151 (49%), Gaps = 7/151 (4%)

Query: 71  TTTDFPVIAQFAANNRDDFV-DASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129
           T +  P   Q   ++ D+   +A + V    D +DLN GCP     +   G  LL +PE+
Sbjct: 71  TFSGTPCTVQLLGSDADNMAANALEAVRFGADKIDLNFGCPAPTVNRHKGGAILLKEPEL 130

Query: 130 IYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQ-QLEKCGVTFLTSMEEHCTKSSG- 187
           I+ IVK LR  LP    ++ K+RL  + K   + C   + + G   LT      TK+ G 
Sbjct: 131 IFHIVKTLRERLPAHIPLTAKMRLGYEDKSPALECACAIAEGGACGLTVHAR--TKAEGY 188

Query: 188 --PVDINGLKEVREALSVPMVANGGVKHLND 216
             P     ++++R+++ +P+ ANG V  L D
Sbjct: 189 EPPAHWEWIRKIRDSVDIPVTANGDVFSLQD 219


>UniRef50_Q8ZAX7 Cluster: tRNA-dihydrouridine synthase B; n=214;
           Proteobacteria|Rep: tRNA-dihydrouridine synthase B -
           Yersinia pestis
          Length = 321

 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 45/195 (23%), Positives = 90/195 (46%), Gaps = 10/195 (5%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILAD-SFCQNSKARANEFMTTTTDFPVI--A 79
           + APM   +   FR L     A +  + M+ ++    +  K+R         D P I   
Sbjct: 13  IAAPMAGITDRPFRALCHGMGAGMAVSEMLSSNPEVWRTDKSRLR---MVHVDEPGIRNV 69

Query: 80  QFAANNRDDFVDASKL-VYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLR 138
           Q A N+ D+   A+++ V      +D+N GCP K   +   G +LL  P+++  I+  + 
Sbjct: 70  QIAGNDPDEMAAAARINVASGAQIIDINMGCPAKKVNRKLAGSALLQHPDLVKQILSAVV 129

Query: 139 NVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT--SMEEHCTKSSGPVDINGLKE 196
           N +    ++ ++     + +  + + Q  E CG+  LT       C   +G  + + ++ 
Sbjct: 130 NAVDVPVTLKIRTGWSPEHRNCIEIAQLAENCGIQALTIHGRTRSCL-FNGEAEYDSIRA 188

Query: 197 VREALSVPMVANGGV 211
           V++ +S+P++ANG +
Sbjct: 189 VKQTVSIPVIANGDI 203


>UniRef50_P37567 Cluster: Probable tRNA-dihydrouridine synthase 1;
           n=31; Bacilli|Rep: Probable tRNA-dihydrouridine synthase
           1 - Bacillus subtilis
          Length = 333

 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 48/198 (24%), Positives = 83/198 (41%), Gaps = 3/198 (1%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           V APM       FR  V+ F A L    M+   +   N+            + P+  Q  
Sbjct: 14  VLAPMAGVCNSAFRLTVKEFGAGLVCAEMVSDKAILYNNARTMGMLYIDEREKPLSLQIF 73

Query: 83  ANNRDDFVDASKLV--YPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140
              ++  V+A+K V      D +D+N GCP     K   G   L  P+ IY++V  + + 
Sbjct: 74  GGKKETLVEAAKFVDQNTTADIIDINMGCPVPKITKCDAGAKWLLDPDKIYEMVSAVVDA 133

Query: 141 LPNKFSISVKIRLLNDIKKTVILCQQLEKC-GVTFLTSMEEHCTKSSGPVDINGLKEVRE 199
           +    ++ +++    D    V   Q +E+  G               G  + + +KEV++
Sbjct: 134 VNKPVTVKMRMGWDEDHIFAVKNAQAVERAGGKAVALHGRTRVQMYEGTANWDIIKEVKQ 193

Query: 200 ALSVPMVANGGVKHLNDA 217
           ++S+P++ NG VK   DA
Sbjct: 194 SVSIPVIGNGDVKTPQDA 211


>UniRef50_A6LGT0 Cluster: Putative TIM-barrel enzyme; n=1;
           Parabacteroides distasonis ATCC 8503|Rep: Putative
           TIM-barrel enzyme - Parabacteroides distasonis (strain
           ATCC 8503 / DSM 20701 / NCTC11152)
          Length = 329

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 47/193 (24%), Positives = 88/193 (45%), Gaps = 8/193 (4%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           APM   + + FR + + F AD+ +T  + +D+  ++      +   +  + PV  Q    
Sbjct: 16  APMEDVTDISFRLMCKRFGADMVYTEFVSSDALIRSVNKTQQKLNVSDDERPVAIQIYGK 75

Query: 85  NRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143
           +    V+A+++      D +D+N GCP K     G G  +L    ++ +I + +  V   
Sbjct: 76  DVASMVEAARICEEARPDILDINFGCPVKKVAGKGAGAGMLRNIPLMLEITREV--VKAV 133

Query: 144 KFSISVKIRLLNDIKKTVI--LCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE- 199
              ++VK RL  D    VI  L +QL+ CG+  L+          +G  D   ++ V+  
Sbjct: 134 NIPVTVKTRLGWDADNRVIVDLAEQLQDCGIAALSIHGRTRAQMYTGEADWTLIRAVKNN 193

Query: 200 -ALSVPMVANGGV 211
             + +P++ NG V
Sbjct: 194 PRMQIPIIGNGDV 206


>UniRef50_Q7R3H4 Cluster: GLP_158_49916_51304; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_158_49916_51304 - Giardia lamblia
           ATCC 50803
          Length = 462

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 50/167 (29%), Positives = 80/167 (47%), Gaps = 12/167 (7%)

Query: 22  KVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKAR---ANEFM-TTTTDFPV 77
           K  APMV  S++ +R L R +  +L +TPM   ++   +SKA     +E     + D P+
Sbjct: 19  KGIAPMVDGSELPYRLLTRRYGVELAWTPMHSTNTLVTSSKAMTQLVDELKHGESIDRPL 78

Query: 78  IAQFAANNRDDFVDASKLVYPY-----VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYD 132
           + Q + NN  +F  A   +         D V+LN GCPQ  A++  YG  L+   ++  +
Sbjct: 79  VLQLSGNNPSNFELAYNTLVQMGAGCCFDVVELNMGCPQAVALRGKYGAYLMGHLDLAEE 138

Query: 133 IVKGLRNVLPNK---FSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176
           I++ L  V         ++VK RL    K TV +C +L   G+   T
Sbjct: 139 ILRTLVAVTARSGLGHKVAVKTRLDISDKDTVKMCLRLCSTGIAMFT 185


>UniRef50_A2QES0 Cluster: Contig An02c0390, complete genome; n=12;
           Pezizomycotina|Rep: Contig An02c0390, complete genome -
           Aspergillus niger
          Length = 446

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 50/155 (32%), Positives = 77/155 (49%), Gaps = 12/155 (7%)

Query: 77  VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136
           +I Q      +  V A+KLV   V G+D+N GCP+ ++   G G +LL  P+ +  I++ 
Sbjct: 105 LIYQIGTATPEIAVQAAKLVAGDVAGIDVNSGCPKPFSTSGGMGAALLKTPDKLVAILEA 164

Query: 137 L-RNV-LPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHC-TKSSGPVD--- 190
           L + V  P +  ISVKIR+L D ++T  L  +L K G+T LT    HC T    P +   
Sbjct: 165 LVKEVGTPFQIGISVKIRILKDPEETRALVSRLVKTGITGLT---VHCRTPPMRPRERAI 221

Query: 191 ---INGLKEVREALSVPMVANGGVKHLNDATTYMK 222
              +  + ++     V  V NG V   ++    MK
Sbjct: 222 RDQVRMIADICHEAGVACVINGDVTSKDEGHALMK 256


>UniRef50_Q6MNE9 Cluster: Nitrogen regulation protein nifR3; n=1;
           Bdellovibrio bacteriovorus|Rep: Nitrogen regulation
           protein nifR3 - Bdellovibrio bacteriovorus
          Length = 352

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 51/220 (23%), Positives = 99/220 (45%), Gaps = 15/220 (6%)

Query: 13  DAKINKTYLKVC-APMVRYSKVHFRTLVRNFNADLCFT----PMILADSFCQNSKARANE 67
           D K+N     +C APMV  + V  R ++R++     +T     M+ +      +  +  E
Sbjct: 11  DGKVN---FPLCLAPMVGLTHVALREVMRDYLPAEAYTIWPTEMLNSRRIPGENLEKTPE 67

Query: 68  FMTTTTDFPVIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSK 126
            M    +  ++ Q   N  D   ++ K +  +  + +D+N GCP + A+K  YG +L+  
Sbjct: 68  TMRAAYEPGLVPQILGNEEDAIAESVKRLVEWGAEAIDINMGCPVQKALKHNYGVALMGD 127

Query: 127 PEIIYDIVKGLRNVLPNKFSISVKIRLLNDIK---KTVILCQQLEKCGVTFL-TSMEEHC 182
           P    ++V+    V  +   +SVK+R +   K   + +     L + G  ++        
Sbjct: 128 PAYAAEVVR--MTVKNSTVPVSVKLRAVGSTKEFDELLTFVSGLRQSGAAWVCLHPRTAA 185

Query: 183 TKSSGPVDINGLKEVREALSVPMVANGGVKHLNDATTYMK 222
            K  G  D   +K++ +A+  P++ NG V+  +DA   +K
Sbjct: 186 QKRRGNADWEQIKQLHKAVDFPVIGNGDVQTYDDAINMLK 225


>UniRef50_Q6AKJ6 Cluster: Putative uncharacterized protein; n=1;
           Desulfotalea psychrophila|Rep: Putative uncharacterized
           protein - Desulfotalea psychrophila
          Length = 354

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 59/198 (29%), Positives = 90/198 (45%), Gaps = 7/198 (3%)

Query: 25  APMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQ-FA 82
           APMV  S    R+L+ +     L +T M+ A      + A ++   TT  + P+I Q F 
Sbjct: 47  APMVGLSHSALRSLIADLGGCGLFYTEMLAARRLPHENPAVSSYLHTTPCERPLIYQLFI 106

Query: 83  ANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
           A+ +       K+     DGVD+N GCP     + G G +L    + + DIV   R    
Sbjct: 107 ADVKYVAPALDKIHRLGGDGVDINLGCPAPSVRRGGAGAALAEDWDRVRDIVSSARR--H 164

Query: 143 NKFSISVKIRLLNDIKKTVIL--CQQLEKCGVTFL-TSMEEHCTKSSGPVDINGLKEVRE 199
              ++S KIR+ +  K+  +L  C+ LE  GV  L      H  K         L  + E
Sbjct: 165 TDLTLSAKIRVGHVGKEAHLLDFCKMLEAEGVDLLAVHARYHGEKFCRKPRWQLLAPICE 224

Query: 200 ALSVPMVANGGVKHLNDA 217
            L +P+ ANGG+  ++DA
Sbjct: 225 QLDIPIFANGGIFSVDDA 242


>UniRef50_Q1Q3Q8 Cluster: Strongly similar to tRNA-dihydrouridine
           synthase; n=1; Candidatus Kuenenia stuttgartiensis|Rep:
           Strongly similar to tRNA-dihydrouridine synthase -
           Candidatus Kuenenia stuttgartiensis
          Length = 341

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 43/202 (21%), Positives = 86/202 (42%), Gaps = 2/202 (0%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           + APM  +S + +R + R F   + +T ++       N+K           + PV  Q  
Sbjct: 36  ILAPMAGFSDMPYRLICRRFGMSMSYTEVVSVSGIVWNNKKTFKLLDFKEEERPVTFQVV 95

Query: 83  ANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141
            N+     +A K +     D +D+N GC        G G  +L  P  I  +   L   L
Sbjct: 96  GNDECQITEACKKIEQLGPDIIDINMGCSVSDIAGKGAGAGMLKHPSKISKMFNNLTGSL 155

Query: 142 PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVREA 200
               +  +++   +  +  + + + LE+ G + +       ++  SG  D + + EV+++
Sbjct: 156 SVPVTGKIRLGWDHKTRNYIEVARILEENGASLIAVHGRTRSQYFSGAADWDAIAEVKQS 215

Query: 201 LSVPMVANGGVKHLNDATTYMK 222
           + +P++ANG V+ + D     K
Sbjct: 216 VKIPVIANGDVRSVADIAEIKK 237


>UniRef50_Q1DPY5 Cluster: Putative uncharacterized protein; n=1;
           Coccidioides immitis|Rep: Putative uncharacterized
           protein - Coccidioides immitis
          Length = 453

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 36/102 (35%), Positives = 59/102 (57%), Gaps = 2/102 (1%)

Query: 77  VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136
           +I Q    N    V+A+K+V   V G+D+N GCP+ ++   G G +LL  P+ +  I++ 
Sbjct: 106 LIFQLGTANPSLAVEAAKVVAADVSGIDVNSGCPKPFSTSGGMGAALLQTPDRLVSILEA 165

Query: 137 LRNVL--PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176
           L   +  P +  ISVKIRLL + ++T  L  ++ + G+T LT
Sbjct: 166 LVEEIGKPYEIGISVKIRLLAEPERTEALVTRVCRTGITGLT 207


>UniRef50_Q7VKU5 Cluster: tRNA-dihydrouridine synthase C; n=118;
           Gammaproteobacteria|Rep: tRNA-dihydrouridine synthase C
           - Haemophilus ducreyi
          Length = 325

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 36/121 (29%), Positives = 60/121 (49%), Gaps = 7/121 (5%)

Query: 102 GVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTV 161
           G+D NCGCP K       G +LL  PE+IY   K +R  +P    +SVK+RL  D     
Sbjct: 96  GIDFNCGCPSKTVNGSHGGAALLKDPELIYCATKAIREAVPKAQPVSVKMRLGWDCASQC 155

Query: 162 I-LCQQLEKCGVTFLTSMEEHCTKSSG----PVDINGLKEVREALSVPMVANGGVKHLND 216
             +   +++ G   +T      TK  G     ++   + ++++ L++P++ANG +   N 
Sbjct: 156 FEIADAIQQAGADEITVHGR--TKQDGYRAERINWQAIGQIQQRLNIPVIANGEILDFNS 213

Query: 217 A 217
           A
Sbjct: 214 A 214


>UniRef50_Q607L4 Cluster: TIM-barrel protein, yjbN family; n=10;
           Proteobacteria|Rep: TIM-barrel protein, yjbN family -
           Methylococcus capsulatus
          Length = 327

 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 42/191 (21%), Positives = 85/191 (44%), Gaps = 2/191 (1%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           + APM   + + FR L R F A L  + MI A    Q ++             P+  Q  
Sbjct: 13  ILAPMAGVTDLPFRRLCRQFGAGLAVSEMISASPALQATRKSRLRQDHRGEPGPISVQIV 72

Query: 83  ANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141
             +  +  +A++       D +D+N GCP K       G +LL   +++ +I++ +   +
Sbjct: 73  GADPREMAEAARRTVDLGADIIDINMGCPAKKVCNVAAGSALLRDEKLVANILEAVVQAV 132

Query: 142 PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREA 200
           P   ++ ++    +  +  V + +  E  G+  LT          +G  + + + EV++A
Sbjct: 133 PVPVTLKIRTGWDSASRNAVSIGKIAESAGIRALTVHGRTRACGFAGAAEYSTITEVKKA 192

Query: 201 LSVPMVANGGV 211
           + +P++ANG +
Sbjct: 193 IGIPVIANGDI 203


>UniRef50_Q0G7A4 Cluster: Nitrogen regulation protein nifr3; n=2;
           Aurantimonadaceae|Rep: Nitrogen regulation protein nifr3
           - Fulvimarina pelagi HTCC2506
          Length = 344

 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 49/202 (24%), Positives = 85/202 (42%), Gaps = 8/202 (3%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           AP+   S V FR L R F A L  + M+ +  F + ++      +    D P +      
Sbjct: 23  APLSGISDVPFRRLSRRFGAGLVVSEMVASGEFVKGAEEGK---LRALRDGPGVHTVQLA 79

Query: 85  NRDDF---VDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG-LRNV 140
            RD       A +L     D +D+N GCP K  +    G +L+ +P++ + IV+  +R  
Sbjct: 80  GRDPIWMEEAARRLADEGADLIDINMGCPAKKVVGGLSGSALMREPDLAFSIVEATVRGA 139

Query: 141 LPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE 199
                S+ +++    D      +  + E  GVT +T           G  D   +  V+ 
Sbjct: 140 GATPVSLKMRLGWCRDSMNAAEIAVRAEAAGVTMITVHGRTRAEFYEGTADWRAICSVKR 199

Query: 200 ALSVPMVANGGVKHLNDATTYM 221
           ++ VP+VANG +   N  +  +
Sbjct: 200 SVGVPVVANGDLTEANQLSAIL 221


>UniRef50_Q127F8 Cluster: Dihydrouridine synthase, DuS; n=3;
           Proteobacteria|Rep: Dihydrouridine synthase, DuS -
           Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 344

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 43/150 (28%), Positives = 69/150 (46%), Gaps = 3/150 (2%)

Query: 71  TTTDFPVIAQFAANNRDDFVD-ASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129
           T    PV AQ   ++     + A++L      G+DLN GCP     + G G SLL +PE 
Sbjct: 65  TLAGVPVRAQLLGSDPACMAENAARLATLGPAGIDLNFGCPAAVVNRHGGGASLLKEPET 124

Query: 130 IYDIVKGLRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGV-TFLTSMEEHCTKSSG 187
           +  IV  +R  +P    +S K+RL  ND  + V     + + G    +            
Sbjct: 125 LLAIVSAVRRAVPAGMPVSAKMRLGYNDDSRAVECALAIAEGGAGELVVHARTKAQAYKP 184

Query: 188 PVDINGLKEVREALSVPMVANGGVKHLNDA 217
           P     + ++R A+ +P+VANG +  ++DA
Sbjct: 185 PAYWERIADIRAAVQIPVVANGEIWTVDDA 214


>UniRef50_Q7R1J1 Cluster: GLP_38_15456_16676; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_38_15456_16676 - Giardia lamblia
           ATCC 50803
          Length = 406

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 49/172 (28%), Positives = 73/172 (42%), Gaps = 14/172 (8%)

Query: 25  APMVRYSKVHFRTLVRNFNAD-------LCFTPMILADSFCQNSKARANEFMTTTTDFPV 77
           APM   S   FR L++   A+         FT M  AD+   NS  R     T      +
Sbjct: 56  APMTHASGAAFRQLIQGHMAEENERTKYTGFTQMYTADALLHNSPLRDAVLSTAAPGEKI 115

Query: 78  IAQFAANNRDDFVDASKLVY--PYVD---GVDLNCGCPQKWAMKDGYGCSLLSKPEIIYD 132
           I Q   NN   F  A++L++  P       +D+N GCP   A   GYG  +     +++ 
Sbjct: 116 ILQLCGNNPSTFRAAAELLHDSPIASQLVALDINLGCPASCASSKGYGFYVAQNWPLVHQ 175

Query: 133 IVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTK 184
           I+    +     F ++ KIR LN I+KT+     L   G + +T    H T+
Sbjct: 176 IISETSSA--RLFPVTCKIRPLNSIEKTIDYMVLLVMSGASGITIHMRHTTR 225


>UniRef50_Q9CLW3 Cluster: tRNA-dihydrouridine synthase B; n=17;
           Pasteurellaceae|Rep: tRNA-dihydrouridine synthase B -
           Pasteurella multocida
          Length = 332

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 44/192 (22%), Positives = 87/192 (45%), Gaps = 8/192 (4%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADS---FCQNSKARANEFMTTTTDFPVIAQF 81
           APM   +   FR +  ++ A L F+ M+  +      + SK R         +     Q 
Sbjct: 15  APMAGITDQPFRRICTHYGAGLTFSEMMSTNPQVWHTEKSKLRLAHHQEAGIN---AVQI 71

Query: 82  AANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140
           A  + D+   A+++   Y  + +D+N GCP K   +   G +LL  P+++  I+  +   
Sbjct: 72  AGCDPDEMAKAAQINVEYGAEIIDINMGCPAKKVNRKMAGSALLQYPDLVKQILNKVVKS 131

Query: 141 LPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE 199
           +    ++ ++     D +  + + +  E+CG+  LT           G  + + +K V+E
Sbjct: 132 VTVPVTLKIRTGWDKDNRNCLEIAKIAEQCGIQALTIHGRTRSCMFEGEAEYDNIKAVKE 191

Query: 200 ALSVPMVANGGV 211
            LS+P++ANG +
Sbjct: 192 QLSIPIIANGDI 203


>UniRef50_P53720 Cluster: tRNA-dihydrouridine synthase 2; n=7;
           Saccharomycetales|Rep: tRNA-dihydrouridine synthase 2 -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 384

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 43/122 (35%), Positives = 71/122 (58%), Gaps = 12/122 (9%)

Query: 100 VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGL-RNV-LPNKFSISVKIRLLNDI 157
           V G+D+N GCP+ +++  G G +LL  P+ +  I+K L +NV  P+   ISVKIRLL+  
Sbjct: 108 VSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVKIRLLDTK 167

Query: 158 KKTVILCQQLEKCGVTFLTSMEEHCTKS-----SGPVD--INGLKEVREALSVPMVANGG 210
           + T+ L ++L   G+T LT    HC K+       P+   I  + E+ +A +V ++ NG 
Sbjct: 168 QDTLQLVKRLCATGITNLT---VHCRKTEMRNREQPITDYIAEIYEICQANNVSLIVNGA 224

Query: 211 VK 212
           ++
Sbjct: 225 IR 226


>UniRef50_Q8XYX1 Cluster: tRNA-dihydrouridine synthase C; n=26;
           Proteobacteria|Rep: tRNA-dihydrouridine synthase C -
           Ralstonia solanacearum (Pseudomonas solanacearum)
          Length = 326

 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 41/151 (27%), Positives = 76/151 (50%), Gaps = 7/151 (4%)

Query: 71  TTTDFPVIAQFAANNRDDFV-DASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129
           T +  P++ Q   ++ +    +A++       G+DLN GCP K   + G G  LL+ PE+
Sbjct: 60  TASGTPMVIQLLGSDPEWLARNAAQAATVSPHGIDLNFGCPAKVVNRHGGGAMLLATPEL 119

Query: 130 IYDIVKGLRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSG- 187
           ++ IV  +R  +P + +++ K+RL ++D    +     L + G   L       T+  G 
Sbjct: 120 LHRIVSTVRAAVPARIAVTAKMRLGVSDTSLAIACATALAEGGAASLVVHAR--TRDHGY 177

Query: 188 --PVDINGLKEVREALSVPMVANGGVKHLND 216
             P   + +  + +A+ VP+VANG V  ++D
Sbjct: 178 RPPAHWDWIARIADAVRVPVVANGEVWTVDD 208


>UniRef50_O52532 Cluster: tRNA-dihydrouridine synthase B; n=6;
           Gammaproteobacteria|Rep: tRNA-dihydrouridine synthase B
           - Serratia marcescens
          Length = 334

 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 45/194 (23%), Positives = 91/194 (46%), Gaps = 8/194 (4%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILAD-SFCQNSKARANEFMTTTTDFPVI--A 79
           + APM   +   FRTL     A +  + M+ ++    +  K+R        +D P I   
Sbjct: 13  IAAPMAGITDRPFRTLCHAMGAGMAVSEMLSSNPEVWRTDKSRLR---MVHSDEPGIRSV 69

Query: 80  QFAANNRDDFVDASKL-VYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLR 138
           Q A  + DD   A+++ V      +D+N GCP K   +   G +LL  P+++  I+  + 
Sbjct: 70  QIAGCDPDDMAAAARINVASGAQLIDINMGCPAKKVNRKLAGSALLQYPDLVKRILHAVV 129

Query: 139 NVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEV 197
           + +    ++ ++     + +  V + Q  E CG+  LT          +G  + + ++ V
Sbjct: 130 DAVDVPVTLKIRTGWAPEHRNCVEIAQLAEDCGIQALTIHGRTRACLFNGDAEYDSIRAV 189

Query: 198 REALSVPMVANGGV 211
           ++++S+P++ANG +
Sbjct: 190 KQSVSIPIIANGDI 203


>UniRef50_A3RPJ2 Cluster: TRNA-dihydrouridine synthase; n=2;
           Proteobacteria|Rep: TRNA-dihydrouridine synthase -
           Ralstonia solanacearum UW551
          Length = 369

 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 36/114 (31%), Positives = 59/114 (51%), Gaps = 6/114 (5%)

Query: 102 GVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRL-LNDIKKT 160
           G+DLN GCP K   + G G  LLS PE+++ IV  +R  +P   +++ K+RL ++D    
Sbjct: 135 GIDLNFGCPAKVVNRHGGGAMLLSTPELLHTIVSAVRAAVPANIAVTAKMRLGVSDTSLA 194

Query: 161 VILCQQLEKCGVTFLTSMEEHCTKSSG---PVDINGLKEVREALSVPMVANGGV 211
           +     L + G   L       T+  G   P   + +  + +A+ VP++ANG V
Sbjct: 195 IDCATALAEGGAASLVVHAR--TRDHGYRPPAHWDWIARIADAVEVPVIANGEV 246


>UniRef50_Q4PAE4 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 766

 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 34/101 (33%), Positives = 56/101 (55%), Gaps = 3/101 (2%)

Query: 100 VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKK 159
           V  VDLNCGCP+ ++   G G ++LS P ++ + +K +R   P   +++ KIRLL   +K
Sbjct: 172 VAAVDLNCGCPKPFSTHAGMGANMLSTPILLCNTLKAMRRAAPAHVAVTCKIRLLPTQEK 231

Query: 160 TVILCQQLEKCGVTFLTSMEEHC-TKSSGPVDINGLKEVRE 199
           T+ L  ++ + G   +  +  HC TK   P +   L  +RE
Sbjct: 232 TLELVDKIVRTGA--IECLTVHCRTKDMRPREPALLHRLRE 270


>UniRef50_A7EHJ6 Cluster: Putative uncharacterized protein; n=2;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Sclerotinia sclerotiorum 1980
          Length = 513

 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 34/102 (33%), Positives = 60/102 (58%), Gaps = 2/102 (1%)

Query: 77  VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136
           +I Q   ++ +  V  +++V   V G+D+N GCP+ ++   G G +LL  P+ +  I++ 
Sbjct: 191 LIFQIGTSDPEKAVQCARMVAADVAGIDVNAGCPKPFSTSGGMGAALLQTPDKLCAILEA 250

Query: 137 L-RNVLPN-KFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176
           L + ++P  +  ISVKIRLL   ++T  L ++L   G+T LT
Sbjct: 251 LVKEIVPEFEIGISVKIRLLETPERTEALVRKLCATGITGLT 292


>UniRef50_A6R3V4 Cluster: Putative uncharacterized protein; n=1;
           Ajellomyces capsulatus NAm1|Rep: Putative
           uncharacterized protein - Ajellomyces capsulatus NAm1
          Length = 461

 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 36/102 (35%), Positives = 57/102 (55%), Gaps = 2/102 (1%)

Query: 77  VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136
           ++ Q    + D  V A+K++   V G+D+N GCP+ ++   G G +LL  P+ +  I+  
Sbjct: 88  LVFQIGTASPDLAVQAAKIIAADVAGIDVNAGCPKPFSTTGGMGAALLQTPDRLVSILTA 147

Query: 137 LRNVL--PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176
           L   +  P +  ISVKIRLL D ++T  L  +L   G+T LT
Sbjct: 148 LVQQVGTPYQIGISVKIRLLADPERTRDLVTRLCATGITGLT 189


>UniRef50_Q08111 Cluster: Probable tRNA-dihydrouridine synthase;
           n=21; Alphaproteobacteria|Rep: Probable
           tRNA-dihydrouridine synthase - Rhodobacter capsulatus
           (Rhodopseudomonas capsulata)
          Length = 324

 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 44/190 (23%), Positives = 78/190 (41%), Gaps = 3/190 (1%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILA-DSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           APM   + + FR +V  F A L  + M+ + +        RA      T   P   Q A 
Sbjct: 17  APMAGITDLPFRRMVARFGAGLVVSEMVASGEMLTAKPSVRAKAQAELTAGLPTSVQLAG 76

Query: 84  NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
                  +A+K+V     + +D+N GCP K       G +L+  P+    +++ +   + 
Sbjct: 77  REAAPMAEAAKIVADMGAEIIDINMGCPAKKVTGGLSGAALMRNPDHALRLIEAVVGAVD 136

Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM-EEHCTKSSGPVDINGLKEVREAL 201
              ++ +++    D      +  + E  GV  +           +G  D   +  VR A+
Sbjct: 137 LPVTLKMRLGWDEDQLNAAEIAARAEAAGVKMIVIHGRTRMQFYTGAADWRAIAAVRAAV 196

Query: 202 SVPMVANGGV 211
           SVP+VANG +
Sbjct: 197 SVPVVANGDI 206


>UniRef50_Q3AZ67 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=20; Cyanobacteria|Rep: Dihydrouridine synthase
           TIM-barrel protein nifR3 - Synechococcus sp. (strain
           CC9902)
          Length = 356

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 45/196 (22%), Positives = 84/196 (42%), Gaps = 4/196 (2%)

Query: 25  APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           +P+   +   FR LVR ++ D L FT M+ A S  +              + P+  Q   
Sbjct: 42  SPLAGVTDKIFRGLVRRWSRDSLLFTEMVNATSL-ELGHGYGKMDDLKAEEGPIAVQLFD 100

Query: 84  NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
           +       A++         +D+N GCP +   K G G  L+  P +   I++ + + + 
Sbjct: 101 HRPHAMAHAARRAEQAGAFLIDINMGCPVRKIAKKGGGSGLIRDPNLATQILEAVVDAVS 160

Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVREAL 201
              ++  ++         +  C+QL+  G   LT       +   G  + N + EV++AL
Sbjct: 161 IPVTVKTRLGWCGSSSDPITWCRQLQNAGAQMLTLHGRTREQGFKGQANWNAIAEVKQAL 220

Query: 202 SVPMVANGGVKHLNDA 217
           ++P++ANG +    DA
Sbjct: 221 TIPVIANGDINSPTDA 236


>UniRef50_Q2RM54 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=1; Moorella thermoacetica ATCC 39073|Rep:
           Dihydrouridine synthase TIM-barrel protein nifR3 -
           Moorella thermoacetica (strain ATCC 39073)
          Length = 334

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 51/202 (25%), Positives = 84/202 (41%), Gaps = 3/202 (1%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           + APM  Y+   FR L R   A L +T MI A     N+K             PV  Q  
Sbjct: 17  IMAPMAGYTDRVFRLLAREAGAALTYTEMISAQGLIYNNKNTHALLDLKGEPGPVAVQLF 76

Query: 83  ANNRDDFVDASKL-VYPYVDGVDLNCGCPQKWAMKDGYGCSLLSK-PEIIYDIVKGLRNV 140
               +    A+++ V      +DLN GCP    +K+G G +L+   P     +   +R  
Sbjct: 77  GREPEIMAAATRIAVAAGAAIIDLNMGCPTPKIVKNGEGSALMRDLPRAAAIVAAMVRAA 136

Query: 141 LPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVRE 199
            P   ++ +++    D    V   + +   G   +       ++  SG  D +  + V+E
Sbjct: 137 GPVPVTVKMRLGWDEDSINVVEAARAVVYAGAAAVAIHGRTRSQFYSGRADWSYFRRVKE 196

Query: 200 ALSVPMVANGGVKHLNDATTYM 221
           A+ VP++ NG V+   DA T +
Sbjct: 197 AVDVPVIGNGDVRTARDAVTML 218


>UniRef50_Q22A31 Cluster: TIM-barrel protein, yjbN family; n=1;
           Tetrahymena thermophila SB210|Rep: TIM-barrel protein,
           yjbN family - Tetrahymena thermophila SB210
          Length = 480

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 39/142 (27%), Positives = 65/142 (45%), Gaps = 5/142 (3%)

Query: 14  AKINKTYLKVCAPMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQNSKARANEFMTTT 72
           A IN   + V APM+  + VHFR  +R      + +T MI   +   N +          
Sbjct: 97  ANINYHTIAV-APMIDITDVHFRNFIRLLTRYSILYTEMIHEQAVHHNIRGPQEFLRFDP 155

Query: 73  TDFPVIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIY 131
              PV+ Q   N+ D+   A+K+      D V+LN GCP        +G  L+ +PE++ 
Sbjct: 156 VQHPVVIQLGGNDPDNLAKAAKICEEIGYDEVNLNVGCPSDRVQSGKFGACLMKEPELVA 215

Query: 132 DIVKGLRNVLPNKFSISVKIRL 153
           +I++ ++        ++VK RL
Sbjct: 216 EIMRKMKEAC--SIPVTVKCRL 235


>UniRef50_O25427 Cluster: Probable tRNA-dihydrouridine synthase;
           n=9; Epsilonproteobacteria|Rep: Probable
           tRNA-dihydrouridine synthase - Helicobacter pylori
           (Campylobacter pylori)
          Length = 328

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 46/205 (22%), Positives = 89/205 (43%), Gaps = 6/205 (2%)

Query: 17  NKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP 76
           NK +L + AP+  Y+ + FR++V+ F  D+  + M+ + S        +     +  +  
Sbjct: 5   NKKWLFL-APLAGYTDLPFRSVVKKFGVDVTTSEMVSSHSLVYAFDKTSKMLEKSPLEDH 63

Query: 77  VIAQFAANNRDDFVDASKLV--YPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134
            +AQ + +      +A + +    +V+G+D NCGCP       G G  LL     +  ++
Sbjct: 64  FMAQISGSKESVVKEAVEKINALEHVNGIDFNCGCPAPKVANHGNGSGLLKDLNHLVKLL 123

Query: 135 KGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT--SMEEHCTKSSGPVDIN 192
           K +R     K + SVK+RL  + K    +   L    V ++               +D  
Sbjct: 124 KTIRENTSKKIT-SVKVRLGFEKKIPKEIAHALNDAPVDYVVVHGRTRSDKYQKDKIDYE 182

Query: 193 GLKEVREALSVPMVANGGVKHLNDA 217
            +  +++ L  P++ANG +  +  A
Sbjct: 183 SIALMKKILKKPVIANGEIDSVKKA 207


>UniRef50_Q8YAB9 Cluster: Lmo0227 protein; n=55; Bacteria|Rep:
           Lmo0227 protein - Listeria monocytogenes
          Length = 331

 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 46/198 (23%), Positives = 79/198 (39%), Gaps = 3/198 (1%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           V APM   S   FR  V+ F A L    MI        +    +       + P+  Q  
Sbjct: 14  VVAPMAGISNSAFRLTVKEFGAGLVCCEMISDKGIAYRNAKTLDMLYIDEKEKPLSLQIF 73

Query: 83  ANNRDDFVDASKLVYPYV--DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140
              ++  V+A+K V      D +D+N GCP    +K   G   L  P  +YD+V  + + 
Sbjct: 74  GGEKETLVEAAKFVAENTTADIIDINMGCPVNKIIKCEAGAKWLLDPNKVYDMVAAVVDA 133

Query: 141 LPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM-EEHCTKSSGPVDINGLKEVRE 199
           +    ++ ++I    +    +      E+ G   +            G  + + L++V+ 
Sbjct: 134 VDKPVTVKMRIGWDEEHVFAIENALAAERAGAAAVAMHGRTRVQMYEGSANWDVLRDVKR 193

Query: 200 ALSVPMVANGGVKHLNDA 217
            L +P +ANG V+   DA
Sbjct: 194 ELKIPFMANGDVRTPEDA 211


>UniRef50_Q7XWZ9 Cluster: OSJNBa0079F16.4 protein; n=8; Oryza
           sativa|Rep: OSJNBa0079F16.4 protein - Oryza sativa
           (Rice)
          Length = 1708

 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 42/150 (28%), Positives = 76/150 (50%), Gaps = 8/150 (5%)

Query: 25  APMVRYSKVHFRTLVRNFNADL-CFTPMILADSFCQNSKARANEFMTTTTD-FPVIAQFA 82
           APM+ ++  H+RTL R  +     +T M++A++   + K   + F+    +  P++ Q  
Sbjct: 68  APMMDWTDNHYRTLARLISKHAWLYTEMVVAETIV-HQKDNLDRFLAFPAEQHPIVLQIG 126

Query: 83  ANNRDDFVDASKLVYPY-VDGVDLNCGCPQ-KWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140
            +N D+   A++L   Y  D ++LNCGCP  K A    +G  L+  PE + D +  +   
Sbjct: 127 GSNLDNLAKATELANAYSYDEINLNCGCPSGKVAGHGCFGARLMFDPEFVGDAMSAI--A 184

Query: 141 LPNKFSISVKIRL-LNDIKKTVILCQQLEK 169
                 +SVK R+ ++D      LC+ ++K
Sbjct: 185 ANCNVPVSVKCRIGVDDRDSYEELCEFVDK 214


>UniRef50_Q6PEH0 Cluster: Zgc:63779; n=8; Chordata|Rep: Zgc:63779 -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 660

 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 51/207 (24%), Positives = 89/207 (42%), Gaps = 11/207 (5%)

Query: 17  NKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP 76
           +K YL   AP+     + FR + + F AD+    M +  +  Q   +         ++  
Sbjct: 315 DKLYL---APLTTCGNLPFRRVCKRFGADITCGEMAMCTNLLQGQASEWALLKRHASEDL 371

Query: 77  VIAQFAANNRDDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134
              Q      D     ++L+     VD VD+N GCP     K G GC L+++      IV
Sbjct: 372 FGVQLEGCFPDTMTRCAELLNQNIDVDFVDINSGCPIDLVYKKGGGCGLMTRTSKFEQIV 431

Query: 135 KGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT----SMEEHCTKSSGPVD 190
           +G+ +VL    ++ ++  +  +      L  +++K GV+ +T    S E+  TK +    
Sbjct: 432 RGMNSVLDVPLTVKIRTGVQQNSNIAHKLIPEMKKWGVSLITLHGRSREQRYTKLADWDY 491

Query: 191 INGLKEVREALSVPMVANGGVKHLNDA 217
           IN   ++  A  VP+  NG +    DA
Sbjct: 492 INTCAQL--AAPVPLFGNGDILSYEDA 516


>UniRef50_A4SY29 Cluster: Dihydrouridine synthase, DuS; n=1;
           Polynucleobacter sp. QLW-P1DMWA-1|Rep: Dihydrouridine
           synthase, DuS - Polynucleobacter sp. QLW-P1DMWA-1
          Length = 347

 Score = 59.3 bits (137), Expect = 7e-08
 Identities = 33/129 (25%), Positives = 65/129 (50%), Gaps = 6/129 (4%)

Query: 27  MVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAANN 85
           M+ ++  H R+  R    + + +T M+   +       R  ++  +    PV+ Q   + 
Sbjct: 1   MMEWTDRHCRSFHRALTTEAVLYTEMVTTGALMHGDVPRHLDY--SQDQHPVVLQLGGSE 58

Query: 86  RDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNK 144
            +D   +++L   +  D +DLNCGCP +   +  +G  L+++P+++ D VK ++N +   
Sbjct: 59  PNDLARSAELAQQWGYDEIDLNCGCPSERVQRGAFGACLMAEPKLVADCVKAMQNAV--D 116

Query: 145 FSISVKIRL 153
             ISVK RL
Sbjct: 117 IPISVKHRL 125


>UniRef50_A6U9Y2 Cluster: Dihydrouridine synthase DuS; n=2;
           Sinorhizobium|Rep: Dihydrouridine synthase DuS -
           Sinorhizobium medicae WSM419
          Length = 385

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 35/148 (23%), Positives = 72/148 (48%), Gaps = 6/148 (4%)

Query: 25  APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           APM+ ++  H+R   R  +   L +T MI+AD+  +  +A+        ++ PV  Q   
Sbjct: 25  APMIDWTDRHYRFFARVLSRHALLYTEMIVADAVLRGDRAKL--LGHDASEHPVALQLGG 82

Query: 84  NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
           N+     +A+++   Y  D +++N GCP        +G  L+ +P ++ D +  ++  + 
Sbjct: 83  NDPVKMAEAARIGEAYGYDEINMNVGCPSDRVQSGTFGACLMQEPALVADCIAAMKAAV- 141

Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKC 170
            +  ++VK R+  D +   +  + L KC
Sbjct: 142 -EIPVTVKCRIGVDDQDPEVALRDLVKC 168


>UniRef50_A4S604 Cluster: Predicted protein; n=1; Ostreococcus
           lucimarinus CCE9901|Rep: Predicted protein -
           Ostreococcus lucimarinus CCE9901
          Length = 287

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 53/208 (25%), Positives = 97/208 (46%), Gaps = 15/208 (7%)

Query: 25  APMVRYSKVHFRTLVRN-FNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVI--AQF 81
           AP+ +     FR L  + F A++  + M  A    + ++           D      AQ 
Sbjct: 7   APLTKGGNAPFRRLCASEFGAEVVVSEMAFARFLAKGARVERARVRRHEGDAGDCFGAQI 66

Query: 82  AANNRDDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139
           A N  ++ V+A+ +       D VDLNCGCP     K G G +LL KP  +  +V+G+ +
Sbjct: 67  ATNAIEEGVNAALIASGEFGADFVDLNCGCPIHETWKRGLGAALLKKPAKLERLVEGIAS 126

Query: 140 VLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLT----SMEEHCTKSSGPVDINGL 194
            +     ++VKIRL ++   +   + + LE  G + +     + E+  TK++   D + +
Sbjct: 127 RI--DVPLTVKIRLGIDSSSQARRIAEGLENAGASAVVVHGRTKEQRYTKAA---DYDVI 181

Query: 195 KEVREALSVPMVANGGVKHLNDATTYMK 222
           +++    ++P++ NG V    DA   M+
Sbjct: 182 RDIVRERNIPIIGNGDVLTWYDARDRME 209


>UniRef50_Q54CU9 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 671

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 42/205 (20%), Positives = 84/205 (40%), Gaps = 3/205 (1%)

Query: 15  KINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTD 74
           +IN     + AP+     + FR + +   AD+    M L     + +K+          +
Sbjct: 319 RINFENQLILAPLTTVGNLPFRRICKRLGADITIGEMALTTKLLEGTKSELALLKRHPCE 378

Query: 75  FPVIAQFAANNRDDFVDASKLVYPYVDG--VDLNCGCPQKWAMKDGYGCSLLSKPEIIYD 132
                Q   +  D  V  ++ +   +D   VD+N GCP       G G +L+ +P+ +  
Sbjct: 379 DKFGVQICGSYVDAAVKCAEFIENEIDADFVDINSGCPIDLVCNMGAGAALMERPKKVEQ 438

Query: 133 IVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDI 191
           +++G+ + L    +I ++I    D      L   L + G   +T        + S   + 
Sbjct: 439 LLRGISSSLSCPTTIKIRIGKSEDAPTAHKLIPSLGEWGACAVTLHGRSRAQRYSRLANW 498

Query: 192 NGLKEVREALSVPMVANGGVKHLND 216
           + +K+  E  S+P++ NG + +  D
Sbjct: 499 DYVKQCSEVSSIPLIGNGDIYNYQD 523


>UniRef50_A7CWF1 Cluster: Putative TIM-barrel protein, nifR3 family;
           n=1; Opitutaceae bacterium TAV2|Rep: Putative TIM-barrel
           protein, nifR3 family - Opitutaceae bacterium TAV2
          Length = 389

 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 49/193 (25%), Positives = 86/193 (44%), Gaps = 6/193 (3%)

Query: 25  APMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           +P+  Y+ +  R  VR         T ++ A S  + SK       T   D P+  Q   
Sbjct: 15  SPLAGYTNLPMRLTVRELGGLGWATTDLVNARSLIERSKGAMKLVETAPGDQPLAIQLFG 74

Query: 84  NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
           +  ++  DA+ +        VD+N GCP K  +  G G +++++      +V+G+   + 
Sbjct: 75  SVPEEMRDAAVICKELGAQSVDVNMGCPVKKVVGIGGGAAMMTELNKTAALVRGMVEAVG 134

Query: 143 NKFSISVKIRL-LNDIKKTV-ILCQQLEKCGV-TFLTSMEEHCTKSSGPVDINGLKEVRE 199
           NK  ++ K+RL  +D   T   L + L   GV              SG V++ G++ V E
Sbjct: 135 NKIPVTAKMRLGWDDANITAPDLARVLADVGVAAIFVHGRTRAQGFSGTVNLAGIRAVVE 194

Query: 200 AL-SVPMVANGGV 211
           A+  +P++ NG V
Sbjct: 195 AVPGLPVIGNGDV 207


>UniRef50_Q9TYN2 Cluster: Putative uncharacterized protein
           Y37E11B.5; n=2; Caenorhabditis|Rep: Putative
           uncharacterized protein Y37E11B.5 - Caenorhabditis
           elegans
          Length = 554

 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 36/133 (27%), Positives = 63/133 (47%), Gaps = 2/133 (1%)

Query: 22  KVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQF 81
           K  AP+     + FR +  ++ AD+    M LA S    + +  +       +     Q 
Sbjct: 206 KYLAPLTTVGNLPFRRICVDYGADITCGEMALATSILSGTASEYSLLKRHPCEKIFGVQL 265

Query: 82  AANNRDDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139
           A    D    AS++V     VD +D+N GCP     + G GC+L S+P+ +++++   ++
Sbjct: 266 AGGFADTMAKASQIVVENFDVDFIDINMGCPIDVVNQKGGGCALPSRPQKLFEVLAATKS 325

Query: 140 VLPNKFSISVKIR 152
           VL     ++VKIR
Sbjct: 326 VLGGCCPLTVKIR 338


>UniRef50_Q9ZED2 Cluster: Probable tRNA-dihydrouridine synthase;
           n=39; Proteobacteria|Rep: Probable tRNA-dihydrouridine
           synthase - Rickettsia prowazekii
          Length = 327

 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 47/199 (23%), Positives = 89/199 (44%), Gaps = 5/199 (2%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIA--Q 80
           + APM   + + FR LV+ F A L  + MI + +    S+ ++ +      D P  A  Q
Sbjct: 14  ILAPMSDVTDLEFRKLVKRFGAGLVVSEMIASRAMIMKSR-QSMQKCAIMHDDPTSACVQ 72

Query: 81  FAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139
            A    D   +A+K+        +DLN GCP K  +    G +L+   ++   I +    
Sbjct: 73  LAGCEPDVIAEAAKMNEDMGAKIIDLNFGCPAKKVVGGYAGSALMRDEQLAAKIFEATVK 132

Query: 140 VLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM-EEHCTKSSGPVDINGLKEVR 198
            +    ++ ++I   ++ +    L +     GV  +T      C   SG  + + ++ V+
Sbjct: 133 AVKIPVTVKMRIGWDDNTRNAPTLAKIAANSGVQMVTVHGRTRCQFYSGNANWDFIRTVK 192

Query: 199 EALSVPMVANGGVKHLNDA 217
           EA+ +P++ANG + +   A
Sbjct: 193 EAVKIPVIANGDITNFAKA 211


>UniRef50_Q9RRP8 Cluster: NifR3 protein; n=2; Deinococcus|Rep: NifR3
           protein - Deinococcus radiodurans
          Length = 406

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 53/196 (27%), Positives = 81/196 (41%), Gaps = 13/196 (6%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPV----I 78
           V APM  YS    R L     A    + MI A      S+    E ++    +P      
Sbjct: 95  VLAPMAGYSDAPMRQLAAEQGALWTVSEMISARGLVLGSE---QESLSLGRPYPGEQGRA 151

Query: 79  AQFAANNRDDFVDASKLVYPYVD--GVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136
            Q    + D   DA      +     +DLN GCP       G  C LL  PE+ Y++V+ 
Sbjct: 152 VQLFGADPDVLADAVGKAEAWFAPAAIDLNLGCPVPKVRGKGGAC-LLQTPEVAYELVRA 210

Query: 137 LRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLK 195
           +R        +S KIRL  D  ++V + Q LE  G   +T        + +G  D + + 
Sbjct: 211 MRQA--TGLDVSAKIRLGWDENRSVEIAQGLEAAGAAVVTVHGRTSAQRYTGNADWDAIG 268

Query: 196 EVREALSVPMVANGGV 211
            V +A+ +P++ +G V
Sbjct: 269 RVAQAVRIPVIGSGDV 284


>UniRef50_Q3IKP0 Cluster: TRNA-dihydrouridine synthase C; n=5;
           Alteromonadales|Rep: TRNA-dihydrouridine synthase C -
           Pseudoalteromonas haloplanktis (strain TAC 125)
          Length = 326

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 58/213 (27%), Positives = 86/213 (40%), Gaps = 16/213 (7%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQNSKA------RANEFMTTTTDF 75
           V APM        R L+ N    DLC T  +     C   K         +    T+   
Sbjct: 4   VLAPMEGVVDFKMRQLLTNVGGFDLCVTEFVRVVDACLPDKVFYRYCPELSNNGLTSAGT 63

Query: 76  PVIAQFAANNRDDFVD-ASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134
           PV  Q          + A K +     G+DLN GCP K   K   G  LL  PE +Y+I+
Sbjct: 64  PVRIQLLGQVAGALAENAVKAISLGSHGIDLNFGCPAKTVNKSKGGAVLLKDPEHMYEII 123

Query: 135 KGLRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHC-TKSSG---PV 189
           K +R+ + +K  +S KIRL  +D   +  +   +   G    +S+  H  TK  G   P 
Sbjct: 124 KAVRDAVDSKHQVSAKIRLGFDDDSNSQEIVDAVVSAGA---SSIAIHARTKRDGYNPPA 180

Query: 190 DINGLKEVREALSVPMVANGGVKHLNDATTYMK 222
               +  + +   + +VANG +  + DA    K
Sbjct: 181 YWEKIPPLIKDKDIAVVANGEIWQVADAMLCQK 213


>UniRef50_A1VHK2 Cluster: Dihydrouridine synthase, DuS; n=4;
           Desulfovibrionaceae|Rep: Dihydrouridine synthase, DuS -
           Desulfovibrio vulgaris subsp. vulgaris (strain DP4)
          Length = 449

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 54/190 (28%), Positives = 84/190 (44%), Gaps = 7/190 (3%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           AP+  YS + FR L R   A +C T M+ A      S    +   TT  D P++ Q    
Sbjct: 37  APLAGYSDLSFRLLCRKAGAAVCCTEMVSAKGLIYYSPGTRDLLATTPEDAPLVVQLFGC 96

Query: 85  NRDDFVDASK-LVYPYVDGVDLNCGCPQKWAMKDGYGCSLL-SKPEIIYDIVKGLRNVLP 142
           + D  V A + L+       DLN GC     +K G G ++L   P+ +      LR    
Sbjct: 97  DPDIMVRAMEPLLEQGFRWFDLNMGCSVPKVVKTGCGAAMLRDVPQALAVARAMLRTAGA 156

Query: 143 NKFSISVKIRLLNDIKKTV--ILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVRE 199
            +  +  K RL  D+ + V   L + L   G  ++T    +  +  SG    + L E+  
Sbjct: 157 GR--VGFKFRLGWDVGQEVWADLGRALADLGAGWVTLHPRYARQGFSGEARWSTLGELVR 214

Query: 200 ALSVPMVANG 209
           A+SVP++A+G
Sbjct: 215 AVSVPVIASG 224


>UniRef50_Q5SMC7 Cluster: TRNA-dihydrouridine synthase; n=2; Thermus
           thermophilus|Rep: TRNA-dihydrouridine synthase - Thermus
           thermophilus (strain HB8 / ATCC 27634 / DSM 579)
          Length = 342

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 52/213 (24%), Positives = 103/213 (48%), Gaps = 19/213 (8%)

Query: 25  APMVRYSKVHFRTLVRNFNADL-CFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           APMV  +  HFR LVR  +  +  +T M +  +  + ++ R   F     + P+  Q A 
Sbjct: 9   APMVDRTDRHFRFLVRQVSLGVRLYTEMTVDQAVLRGNRERLLAFRPE--EHPIALQLAG 66

Query: 84  NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
           ++     +A+++   +  D ++LN GCP + A + GYG  LL     + +I+K +   + 
Sbjct: 67  SDPKSLAEAARIGEAFGYDEINLNLGCPSEKAQEGGYGACLLLDLARVREILKAMGEAV- 125

Query: 143 NKFSISVKIRLLNDIKKTVI-LCQQLE---KCGV--------TFLTSMEEHCTKSSGPVD 190
            +  ++VK+RL  + K+T   L Q +E   + GV        + L ++     +   P+ 
Sbjct: 126 -RVPVTVKMRLGLEGKETYRGLAQSVEAMAEAGVKVFVVHARSALLALSTKANREIPPLR 184

Query: 191 INGLKEVR-EALSVPMVANGGVKHLNDATTYMK 222
            + +  ++ +   +  V NGG++ L +A  ++K
Sbjct: 185 HDWVHRLKGDFPQLTFVTNGGIRSLEEALFHLK 217


>UniRef50_Q5LQV9 Cluster: TRNA-dihydrouridine synthase A; n=46;
           Bacteria|Rep: TRNA-dihydrouridine synthase A -
           Silicibacter pomeroyi
          Length = 344

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 34/141 (24%), Positives = 67/141 (47%), Gaps = 4/141 (2%)

Query: 24  CAPMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           CAPM+ ++  H R L R  +   L +T M+ A +  +       E+  +  + PV  Q  
Sbjct: 15  CAPMMDWTDRHCRYLHRLLSRQTLLYTEMVTAPALVRGGALHLLEY--SVEEHPVALQLG 72

Query: 83  ANNRDDFVDASKL-VYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141
            ++ ++   A++L      D ++LNCGCP        +G  L+  P ++ D V  +R  +
Sbjct: 73  GSDPEELAQAARLGAEAGYDEINLNCGCPSDRVQSGTFGAVLMKHPGLVADCVTAMREAV 132

Query: 142 PNKFSISVKIRLLNDIKKTVI 162
             + ++  +I + +   +TV+
Sbjct: 133 DVEVTVKCRIGVDDQDPETVL 153


>UniRef50_Q4FQ57 Cluster: Possible tRNA-dihydrouridine synthase;
           n=5; Moraxellaceae|Rep: Possible tRNA-dihydrouridine
           synthase - Psychrobacter arcticum
          Length = 350

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 1/120 (0%)

Query: 103 VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRL-LNDIKKTV 161
           +D+N GCP K       G  LL +PE++YDI+  +R  +P    +S KIRL   D  +  
Sbjct: 127 IDINFGCPAKTVNSHRGGSVLLDEPEVMYDIISAVRQAVPANIPVSAKIRLGYTDTSRMD 186

Query: 162 ILCQQLEKCGVTFLTSMEEHCTKSSGPVDINGLKEVREALSVPMVANGGVKHLNDATTYM 221
            +   +   G  +LT      T+   P       +   +L +P++ANG + +   A   M
Sbjct: 187 DIRGAIAASGADWLTIHARTKTQGYKPPAYWDKIQAFNSLKIPVIANGEIWNSEHAQNCM 246


>UniRef50_Q1QZQ6 Cluster: Dihydrouridine synthase, DuS; n=1;
           Chromohalobacter salexigens DSM 3043|Rep: Dihydrouridine
           synthase, DuS - Chromohalobacter salexigens (strain DSM
           3043 / ATCC BAA-138 / NCIMB13768)
          Length = 340

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 5/118 (4%)

Query: 103 VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL-PNKFSISVKIRLLNDIKKTV 161
           VDLN GCP K   +   G SLL +PE ++ +V+ +   L P   +++ KIRL  D K   
Sbjct: 99  VDLNFGCPAKTVNRHDGGASLLRQPERVHTVVRAVAEALAPLGIAVTAKIRLGFDDKHVA 158

Query: 162 ILCQQLEKCGVTFLTSMEEHCTKSSG---PVDINGLKEVREALSVPMVANGGVKHLND 216
           + C +  + G      +    T+  G   P     +  ++  LS+P++ANG +  L D
Sbjct: 159 LACAEAAESGGAAHLVVHAR-TRREGYRPPAHWEWIGRIQARLSIPVIANGDIWTLED 215


>UniRef50_A6W1E8 Cluster: Dihydrouridine synthase DuS; n=1;
           Marinomonas sp. MWYL1|Rep: Dihydrouridine synthase DuS -
           Marinomonas sp. MWYL1
          Length = 335

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 43/146 (29%), Positives = 65/146 (44%), Gaps = 7/146 (4%)

Query: 71  TTTDFPVIAQFAANNRDDFVDAS-KLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129
           TT + PV  Q   +N +   +++          +D+N GCP K     G G  LL  P+ 
Sbjct: 77  TTHNHPVHTQLLGSNAELMAESALNATKAGAKHIDVNFGCPAKRVNGHGGGSVLLQTPDA 136

Query: 130 IYDIVKGLRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSG- 187
           +YDI+  +R+ LP+   +S KIRL   D          +E  GV  LT      TK  G 
Sbjct: 137 LYDIMSAIRDTLPSDIPVSAKIRLGFEDEALLFDNVAAIEAAGVGTLTIHGR--TKKDGY 194

Query: 188 --PVDINGLKEVREALSVPMVANGGV 211
             P     + E++    + +VANG +
Sbjct: 195 KPPARWEKIGEIQAKTKMTVVANGDI 220


>UniRef50_Q96G46 Cluster: tRNA-dihydrouridine synthase 3-like; n=12;
           Eutheria|Rep: tRNA-dihydrouridine synthase 3-like - Homo
           sapiens (Human)
          Length = 650

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 49/205 (23%), Positives = 85/205 (41%), Gaps = 10/205 (4%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           AP+     + FR + + F AD+    M +  +  Q   +          +     Q    
Sbjct: 310 APLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALLKRHQCEDIFGVQLEGA 369

Query: 85  NRDDFVDASKLVYPYV--DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
             D     ++L+   V  D VD+N GCP     K G GC+L+++      IV+G+  VL 
Sbjct: 370 FPDTMTKCAELLSRTVEVDFVDINVGCPIDLVYKKGGGCALMNRSTKFQQIVRGMNQVLD 429

Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT----SMEEHCTKSSGPVDINGLKE-V 197
              ++ ++  +   +     L  +L   GV  +T    S E+  TK +   D   ++E V
Sbjct: 430 VPLTVKIRTGVQERVNLAHRLLPELRDWGVALVTLHGRSREQRYTKLA---DWQYIEECV 486

Query: 198 REALSVPMVANGGVKHLNDATTYMK 222
           + A  +P+  NG +    DA   M+
Sbjct: 487 QAASPMPLFGNGDILSFEDANRAMQ 511


>UniRef50_Q8GQD1 Cluster: NifR; n=5; Leptospira|Rep: NifR -
           Leptospira interrogans
          Length = 329

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 41/195 (21%), Positives = 82/195 (42%), Gaps = 2/195 (1%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           +PM   S    R + R F A   +T  +  D     +      F     + P+  Q   N
Sbjct: 16  SPMAGISDSPTRRICRKFGAAFSYTEFVNTDELVHRAPKALKMFRYKLEERPITFQIFGN 75

Query: 85  NRDDFVDASKLVYPYV-DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143
             +   +A++++     D +DLN GC  +     G G  LL +P +   I++ ++  +  
Sbjct: 76  RLEIIAEAAEIIQELKPDIIDLNMGCSTRKVSLRGAGAGLLRRPLLAGKIIEAIKKRVNI 135

Query: 144 KFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVREALS 202
             +  ++I   +  +  + + + LE+ GV  LT        + +G  D + + E++    
Sbjct: 136 PVTAKIRIGWDSTSRNYLEVSKILEESGVDALTVHGRTKEMAYTGFADWDAIGEIKVNRK 195

Query: 203 VPMVANGGVKHLNDA 217
           +P+  NG +K   +A
Sbjct: 196 IPIFGNGDIKSFQEA 210


>UniRef50_A3JG66 Cluster: Putative uncharacterized protein; n=3;
           Gammaproteobacteria|Rep: Putative uncharacterized
           protein - Marinobacter sp. ELB17
          Length = 335

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 32/111 (28%), Positives = 54/111 (48%), Gaps = 2/111 (1%)

Query: 103 VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVI 162
           VD+N GCP K   K   GC L+ +PE++++I   +R  +P    ++ K+RL  D +   +
Sbjct: 92  VDINFGCPAKTVNKHKGGCVLMREPELMHEITAAVRQAVPADILVTAKMRLGYDDRSMGV 151

Query: 163 LC-QQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVREALSVPMVANGGV 211
            C Q L+  G   +       T     P     + + REA+   ++ANG +
Sbjct: 152 ACAQALDAAGAGEIVIHARSKTDGYKPPAYWEEIAKAREAVKAKVIANGDI 202


>UniRef50_A5D5Q0 Cluster: TRNA-dihydrouridine synthase; n=5;
           Firmicutes|Rep: TRNA-dihydrouridine synthase -
           Pelotomaculum thermopropionicum SI
          Length = 324

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 50/204 (24%), Positives = 85/204 (41%), Gaps = 6/204 (2%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           + APM   +   FR L R F   L  T M+   +    +    +         PV  Q  
Sbjct: 13  IAAPMAGITDKAFRILAREFGCGLVCTEMVSDQALLHGNPKTCSLLDVAGEAGPVSVQIF 72

Query: 83  ANNRDDFVDASKLVYPYVDGV-DLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141
            +N     +A+ +      G+ D+N GCP    +K+G G +L+ +PE    IV+ +  V 
Sbjct: 73  GSNAACMAEAAGIAESRGAGIIDINMGCPTPKIVKNGEGAALMREPEKAARIVRAV--VE 130

Query: 142 PNKFSISVKIR--LLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVR 198
             K  ++VK+R    ++    V L +   + G   +T          +G  D   +  V+
Sbjct: 131 RVKVPVTVKMRKGWDDNSPNAVELARLAAEAGAAAVTVHGRTRSQLYAGKADWEIIAAVK 190

Query: 199 EALSVPMVANGGVKHLNDATTYMK 222
            A+ VP++ NG V    DA   ++
Sbjct: 191 RAVDVPVIGNGDVWTPQDALAMLE 214


>UniRef50_Q9LY64 Cluster: Putative uncharacterized protein
           MAA21_140; n=4; Arabidopsis thaliana|Rep: Putative
           uncharacterized protein MAA21_140 - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 456

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 35/111 (31%), Positives = 59/111 (53%), Gaps = 5/111 (4%)

Query: 25  APMVRYSKVHFRTLVRNFNADL-CFTPMILADSFCQNSKARANEFMT-TTTDFPVIAQFA 82
           APM+ ++  H+RTL R        +T MI A++   + +   + F+  +    P++ Q  
Sbjct: 42  APMMDWTDNHYRTLARLITKHAWLYTEMIAAETLV-HQQTNLDRFLAFSPQQHPIVLQLG 100

Query: 83  ANNRDDFVDASKLVYPY-VDGVDLNCGCPQ-KWAMKDGYGCSLLSKPEIIY 131
            +N ++   A+KL   Y  D ++LNCGCP  K A    +G SL+ KP++ Y
Sbjct: 101 GSNVENLAKAAKLSDAYGYDEINLNCGCPSPKVAGHGCFGVSLMLKPKVRY 151


>UniRef50_Q9Z7D8 Cluster: Predicted oxidoreductase; n=7;
           Chlamydiaceae|Rep: Predicted oxidoreductase - Chlamydia
           pneumoniae (Chlamydophila pneumoniae)
          Length = 335

 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 38/132 (28%), Positives = 64/132 (48%), Gaps = 5/132 (3%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDF-PVIAQF 81
           V AP+  +S   +R +   +   L F  M+  +     +  R ++ +    +  P+ AQ 
Sbjct: 17  VYAPLAGFSDYPYRCMSALYQPGLMFCEMVKVEGILY-APERTSKLLDYNENMRPIGAQL 75

Query: 82  AANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140
             +N +   +A+K++     D +DLNCGCP     KDG G  LL  PE+I  I+  + N 
Sbjct: 76  CGSNPETSGEAAKILEGLGFDLIDLNCGCPTDKITKDGSGSGLLKTPELIGRILDKIINS 135

Query: 141 LPNKFSISVKIR 152
           +     ++VKIR
Sbjct: 136 V--SIPVTVKIR 145


>UniRef50_Q5LRN6 Cluster: TRNA-dihydrouridine synthase, putative;
           n=10; Rhodobacterales|Rep: TRNA-dihydrouridine synthase,
           putative - Silicibacter pomeroyi
          Length = 327

 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 46/193 (23%), Positives = 85/193 (44%), Gaps = 6/193 (3%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIA-QF 81
           + APM   +   FR LV  F A +  + M+ +    Q +K    E    + D    A Q 
Sbjct: 15  ILAPMAGITDRPFRDLVMEFGAGMVVSEMVASQEMVQ-AKPGVRERAELSADVENTAVQL 73

Query: 82  AANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGY-GCSLLSKPEIIYDIVKGLRN 139
           A  +     +A++ V       +D+N GCP K  + +GY G +LL  P+    +++ +  
Sbjct: 74  AGRDTHWIAEAARQVADRGARVIDINMGCPAK-KVTNGYSGSALLKTPDHALRLIEAVVA 132

Query: 140 VLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM-EEHCTKSSGPVDINGLKEVR 198
            +    ++  ++   + +     + ++  + GV  +T      C    G  D   +  VR
Sbjct: 133 AVDVPVTLKTRLGWDDTLMNAPDVARRAAEAGVRMVTIHGRTRCQFYKGRADWAAIAAVR 192

Query: 199 EALSVPMVANGGV 211
           EA+ VP++ANG +
Sbjct: 193 EAVDVPLIANGDI 205


>UniRef50_Q4QEF9 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 595

 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 46/201 (22%), Positives = 87/201 (43%), Gaps = 10/201 (4%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           V AP+     + FR + ++F AD+  + M +  +  +  K+  +      ++     Q A
Sbjct: 238 VLAPLTTVGNLPFRRICKSFGADVTLSEMAVVFNLNRLQKSEWSLLRRHESEDIFGIQLA 297

Query: 83  ANNRDD---FVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139
            +   +   F  A +      D +D+NCGCP +  +K G GC L  + E + D+V+ L  
Sbjct: 298 VSRPQEAATFAQALEASGFSYDFLDINCGCPVEKIVKSGCGCGLWQRTERLRDVVESLAI 357

Query: 140 VLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT----SMEEHCTKSSGPVDINGLK 195
                 +I  +I L  DI        +    G   +T    S ++  TK +   + + + 
Sbjct: 358 YQSRPVAIKCRIGLDEDIPTLHQQIHRYSAWGAAAVTVHGRSRKQRYTKFA---NWDYVD 414

Query: 196 EVREALSVPMVANGGVKHLND 216
           +  +  S+P++ NG +  L D
Sbjct: 415 QCAQLTSLPVIGNGDIMSLED 435


>UniRef50_A4EC62 Cluster: Putative uncharacterized protein; n=1;
           Collinsella aerofaciens ATCC 25986|Rep: Putative
           uncharacterized protein - Collinsella aerofaciens ATCC
           25986
          Length = 347

 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 42/224 (18%), Positives = 88/224 (39%), Gaps = 7/224 (3%)

Query: 4   ICDIMEKFADAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKA 63
           +C+   +   A   + +L   APM   +   +R + R   A+L ++ M+        S  
Sbjct: 3   LCEYSTRLLGAYAEQPFLM--APMAGVTDPAYRIMCRRRGANLAYSEMVSVAGLAYASNK 60

Query: 64  RANEFMTTTTDFPVIAQFAANNRDDFVDASKLVYPYVDG----VDLNCGCPQKWAMKDGY 119
                +    +  +  Q   +  + F  A   V   V      +D+N  CP +  +  G 
Sbjct: 61  TWRLVLPADEEQQICVQLFGSKPEQFASAVAAVEERVGDRLSLIDINMACPARKVVTKGE 120

Query: 120 GCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSME 179
           G +L+  P++   IV+          ++ ++     + +      Q LE  G   +    
Sbjct: 121 GSALMRTPDLAEKIVEAAVGAAHVPVTVKIRKGFYAEDRNAATFAQMLEGAGAAAVAVHG 180

Query: 180 EHCTK-SSGPVDINGLKEVREALSVPMVANGGVKHLNDATTYMK 222
              T+  +G  D + + EV +A+ +P++ +G V    DA  +++
Sbjct: 181 RCATQLYTGQADWSVVDEVADAVEIPVIGSGDVFSAEDAAEHLQ 224


>UniRef50_Q251N6 Cluster: Putative uncharacterized protein; n=2;
           Desulfitobacterium hafniense|Rep: Putative
           uncharacterized protein - Desulfitobacterium hafniense
           (strain Y51)
          Length = 326

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 51/204 (25%), Positives = 98/204 (48%), Gaps = 10/204 (4%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDF-PVIAQFAA 83
           APM   +   FR  VR+      +T MI +D       +R  E +  + +  P I Q   
Sbjct: 20  APMAGVTDKAFRETVRSVGGLHVWTEMI-SDKALTYMNSRTLEMLDLSGEASPRIVQLFG 78

Query: 84  NNRDDFVDASKL-VYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
           +  +    A+ L V    + +D+N GCP    +K+G G +LL    +   I + +   + 
Sbjct: 79  SEPEVMAKAAALAVERDAEIIDINMGCPTPKIVKNGEGSALLQDLPLAQRIAEAVVKAV- 137

Query: 143 NKFSISVKIRLLNDIKKTVI--LCQQLEKCGVTFLTSMEEHCTKS--SGPVDINGLKEVR 198
            +  ++VK+RL    ++ V   L +++E  GV  + S+     +   +G  + +G+K+V+
Sbjct: 138 -EVPVTVKMRLGWTAERIVAPELAKRVEAVGVQ-MVSVHGRTREQFYAGTANRDGIKKVK 195

Query: 199 EALSVPMVANGGVKHLNDATTYMK 222
             +S+P++ANG +    +A T ++
Sbjct: 196 GGVSIPVIANGDIFSPQEAKTVLE 219


>UniRef50_Q55724 Cluster: Probable tRNA-dihydrouridine synthase 1;
           n=15; Cyanobacteria|Rep: Probable tRNA-dihydrouridine
           synthase 1 - Synechocystis sp. (strain PCC 6803)
          Length = 355

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 52/193 (26%), Positives = 88/193 (45%), Gaps = 10/193 (5%)

Query: 25  APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           +P+   + + FR LVR +    + +T M+ A     + +           + P+  Q   
Sbjct: 47  SPLSGVTDLVFRRLVRRYAPQAMLYTEMVSATEI-HHLRTLPQVMEIDPRENPISIQLF- 104

Query: 84  NNRDDFVD--ASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141
           + R DF+   A K V      VD+N GCP     K G G SLL +P +   IVK +  V 
Sbjct: 105 DCRPDFMAEAAQKAVAQGAQSVDINMGCPVNKITKKGGGSSLLRQPAVAEAIVKTV--VA 162

Query: 142 PNKFSISVKIRL-LNDIKKTVI-LCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVR 198
                ++VK RL  +D +  ++   Q+L+  G   LT          +G      + +V+
Sbjct: 163 AVDVPVTVKTRLGWDDGEINIVEFAQRLQDAGAQMLTLHGRTRAQGYNGRARWQWIAKVK 222

Query: 199 EALSVPMVANGGV 211
           +AL++P++ANG +
Sbjct: 223 QALTIPVIANGDI 235


>UniRef50_Q1VN28 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=1; Psychroflexus torquis ATCC 700755|Rep:
           Dihydrouridine synthase TIM-barrel protein nifR3 -
           Psychroflexus torquis ATCC 700755
          Length = 338

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 44/190 (23%), Positives = 82/190 (43%), Gaps = 5/190 (2%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           APM   + + +R L +   AD   T    A    + +     +  T   + P I Q    
Sbjct: 17  APMAGVTDLAYRLLAKECGADFTVTEFTAASGLTRKNTNSWLKVETDPREKPFIPQIFGG 76

Query: 85  NRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNK 144
           +  +      ++    D +D+N GCP     ++  G +LL  P+ +  +V+  R +    
Sbjct: 77  DISEMAKTVGMLEDRSDVIDINFGCPAPKVCRNDAGAALLRDPDKVVSMVR--RCIESTN 134

Query: 145 FSISVKIRL-LNDIKKTVI-LCQQLEKCGVTFLTSMEEHC-TKSSGPVDINGLKEVREAL 201
             I+VK+RL       T + + ++L   GV  +         + SG  D + +KE+  ++
Sbjct: 135 VPITVKMRLGTGSGPNTALEISKRLADEGVMRICVHGRTLRQRYSGIADWDQIKEISNSV 194

Query: 202 SVPMVANGGV 211
            +P++ANG V
Sbjct: 195 DIPVIANGDV 204


>UniRef50_Q7R9R0 Cluster: Uncharacterized protein family UPF0034,
           putative; n=7; Plasmodium|Rep: Uncharacterized protein
           family UPF0034, putative - Plasmodium yoelii yoelii
          Length = 531

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 35/131 (26%), Positives = 65/131 (49%), Gaps = 5/131 (3%)

Query: 25  APMVRYSKVHFRTLVRNFNADL-CFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           APM+  +  HFR LVR  +  +  +T MI+ ++   N             + P++ Q   
Sbjct: 157 APMINVTNRHFRALVRIISKKVQLWTEMIVDNTLLYNINNLEEHLGFNKNEHPIVCQLGG 216

Query: 84  NNRDDFVDASKLV-YPYVDGVDLNCGCPQ-KWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141
           ++     +A+ LV     D +++N GCP  K A K  +G  L+  P+++ +IV  ++  +
Sbjct: 217 SDPTSLSEAAILVEQAGYDEININVGCPSTKVANKGAFGAYLMKNPQLVKNIVYEIKKKV 276

Query: 142 PNKFSISVKIR 152
             +  ++VKIR
Sbjct: 277 --QIPVTVKIR 285


>UniRef50_Q7R684 Cluster: GLP_574_116690_118078; n=1; Giardia
           lamblia ATCC 50803|Rep: GLP_574_116690_118078 - Giardia
           lamblia ATCC 50803
          Length = 462

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 4/101 (3%)

Query: 76  PVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPE-IIYDIV 134
           P++ Q   N  DD      ++ P+  G+DLN GC  ++A+  G G  L+ K E +I   +
Sbjct: 97  PLVVQLTVNEYDDVDKICSILAPWCVGIDLNLGCGAQFAVSGGRGQRLVDKAENVIARFL 156

Query: 135 KGLRNVLPN---KFSISVKIRLLNDIKKTVILCQQLEKCGV 172
           K L+ +  +   + S S+K RLL  +++TV       K GV
Sbjct: 157 KALQQIEDSGGRRISFSIKQRLLGSVEETVNKMCAFYKLGV 197


>UniRef50_Q21L63 Cluster: Dihydrouridine synthase, DuS; n=1;
           Saccharophagus degradans 2-40|Rep: Dihydrouridine
           synthase, DuS - Saccharophagus degradans (strain 2-40 /
           ATCC 43961 / DSM 17024)
          Length = 318

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 4/117 (3%)

Query: 103 VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVI 162
           +DLN GCP K   +   G  LL + + ++DIV  +R   P    ++ KIR L  + +   
Sbjct: 97  IDLNFGCPAKTVNRHKGGACLLDETDTVFDIVNAVRKATPASTPVTAKIR-LGYLNRDSY 155

Query: 163 L--CQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVREALSVPMVANGGVKHLND 216
           L   + +E  G   L       T     P   + + ++R+ LS+P+VANG +  L D
Sbjct: 156 LRNAKAIEAAGANELCVHARSKTDGYQPPAYWHYIGDIRDNLSIPVVANGEIWSLED 212


>UniRef50_A7DPL5 Cluster: Putative TIM-barrel protein, nifR3 family;
           n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
           Putative TIM-barrel protein, nifR3 family - Candidatus
           Nitrosopumilus maritimus SCM1
          Length = 320

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 52/205 (25%), Positives = 86/205 (41%), Gaps = 15/205 (7%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDF--------P 76
           APM   S    R   +   A L  T      S     + +  E M T  +F        P
Sbjct: 12  APMAGVSDPALRLQCKKMGAGLVVTEFTSIHSIIAKEE-QLKENMKTIQEFIEFSEQERP 70

Query: 77  VIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136
           +  Q   ++      A+ +V PY D +D N GCP     +   G +LL +  +   I + 
Sbjct: 71  ISVQLFGSDLYALEKAATIVEPYFDIIDYNMGCPAPHITQQMAGGALLQEVNLTQQIFET 130

Query: 137 LRNVLPNKFSISVKIRL-LNDIKKTVI--LCQQLEKCGVTFLTSMEEHCTKS-SGPVDIN 192
           L N +  K  +++KIR  + D  K +   + +  E  G+  +T      ++  SG  D  
Sbjct: 131 LVNAV--KKPVTLKIRSGVTDASKFLFRDIAEIAEDQGIQMITFHPRTVSQGYSGSADWK 188

Query: 193 GLKEVREALSVPMVANGGVKHLNDA 217
            +KE++E  ++P+V NG +    DA
Sbjct: 189 LIKELKEISNIPVVGNGDITTPEDA 213


>UniRef50_UPI00015B6197 Cluster: PREDICTED: similar to CG10463-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           CG10463-PA - Nasonia vitripennis
          Length = 584

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 48/198 (24%), Positives = 79/198 (39%), Gaps = 8/198 (4%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           AP+     + FR + + F AD+    M LA    +  +          ++     Q A N
Sbjct: 295 APLTTVGNLPFRRICKEFGADITCGEMALAPRLLKGVREEWALVKRHESEDLFGVQIAGN 354

Query: 85  NRDDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
           N        +L+     VD VDLN GCP     K G GC +L++  I+  +VK    VL 
Sbjct: 355 NPGVLTRCCQLLNDETEVDFVDLNVGCPIDLVYKQGGGCGMLNRLNILESVVKSATEVLD 414

Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT----SMEEHCTKSSGPVDINGLKEVR 198
             F++  +  +  D      L  + +  G + +     S E+  TK +    I    +V 
Sbjct: 415 IPFTVKTRTGVYADKPIAHKLMSKFKDWGASMINIHGRSREQRYTKLADWDYIEKCAQV- 473

Query: 199 EALSVPMVANGGVKHLND 216
            A  +P+   G +   +D
Sbjct: 474 -ASPIPVYGTGDILSWDD 490


>UniRef50_Q0VPD7 Cluster: TIM-barrel protein, yjbN family; n=4;
           Bacteria|Rep: TIM-barrel protein, yjbN family -
           Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM
           11573)
          Length = 348

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 49/213 (23%), Positives = 97/213 (45%), Gaps = 20/213 (9%)

Query: 25  APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           APM+ ++   +R L R      L +T M++A +     + R  +F     + PV  Q   
Sbjct: 37  APMMDWTTRDYRFLARLITRHTLLYTEMVVAQAILHGDRDRFLDF--NDEEHPVALQLGG 94

Query: 84  NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
           ++      A+++   Y  D ++LN GCP     +   G  L+++PE++   V+ ++  + 
Sbjct: 95  SDPQQLAQATRIAGDYGYDEINLNVGCPSDRVQQGKIGAILMAEPELVARCVEAMQAEV- 153

Query: 143 NKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS--SG----------PV 189
               ++VK R+ ++D      L + +++   +  TS+  H  K+  SG          P+
Sbjct: 154 -TVPVTVKTRIGIDDQDDYDFLYRFVDRMEASGCTSLTIHARKAILSGLSPKENRDIPPL 212

Query: 190 DINGLKEVREAL-SVPMVANGGVKHLNDATTYM 221
                  ++ A   + ++ NGGVK LN+   +M
Sbjct: 213 IYQRAYAIKHAFPHIEIILNGGVKTLNEVHEHM 245


>UniRef50_Q91XI1 Cluster: tRNA-dihydrouridine synthase 3-like; n=7;
           Euteleostomi|Rep: tRNA-dihydrouridine synthase 3-like -
           Mus musculus (Mouse)
          Length = 637

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 47/204 (23%), Positives = 82/204 (40%), Gaps = 8/204 (3%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           AP+     + FR + + F AD+    M +  +  Q   +          +     Q    
Sbjct: 297 APLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALLKRHPCEDIFGVQLEGA 356

Query: 85  NRDDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
             D     ++L+     VD VD+N GCP     K G GC+L+++      IV+G+  VL 
Sbjct: 357 FPDTMTKCAELLNRTIDVDFVDINVGCPIDLVYKKGGGCALMNRSAKFQQIVRGVNGVLD 416

Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT----SMEEHCTKSSGPVDINGLKEVR 198
              ++ ++  +   +     L  +L   GV  +T    S E+  T+ +    I    +V 
Sbjct: 417 VPLTVKMRTGVQERVSLAHRLLPELRDWGVALVTLHGRSREQRYTRLADWPYIEQCAKV- 475

Query: 199 EALSVPMVANGGVKHLNDATTYMK 222
            A  +P+  NG +    DA   M+
Sbjct: 476 -ASPMPLFGNGDILSFEDANCAMQ 498


>UniRef50_A4RQU5 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 608

 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 49/211 (23%), Positives = 84/211 (39%), Gaps = 9/211 (4%)

Query: 17  NKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP 76
           +K YL   AP+     + FR + +   AD+    M L  S  Q   +         ++  
Sbjct: 247 DKLYL---APLTTVGNLPFRRVCKTLGADITCGEMALCTSLLQGLPSEWALLRRHKSEDI 303

Query: 77  VIAQFAANNRDDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134
              Q      D      +L+     VD +D+N GCP     + GYG  +L KP+ +  ++
Sbjct: 304 FGVQICGGYPDSVTRCCQLLEDTIDVDFIDINMGCPIDSVCQKGYGSMMLEKPKKMETVI 363

Query: 135 KGLRNVLPNKFSISVKIRLLNDIKKTV--ILCQQLEKCGVTFLT-SMEEHCTKSSGPVDI 191
           +     L  K S++ K R+    K  V      ++ + G   +T        +     D 
Sbjct: 364 RAASAAL-GKCSLTFKTRMAYTDKSRVAHTFAPKVAEWGAAAMTLHGRTRAQRYRSVADW 422

Query: 192 NGLKEVREALSVPMVANGGVKHLNDATTYMK 222
              K  +E+ SVP++ NG V    D  T+++
Sbjct: 423 EYTKLTKESSSVPLIGNGDVYMQKDYYTHLE 453


>UniRef50_Q8YMN5 Cluster: Transcriptional regulator; n=5;
           Bacteria|Rep: Transcriptional regulator - Anabaena sp.
           (strain PCC 7120)
          Length = 349

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 50/206 (24%), Positives = 88/206 (42%), Gaps = 8/206 (3%)

Query: 21  LKVCAPMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQNSKARANEFMTTTTDFPVIA 79
           L   APM   + + F  ++ ++ + D  FT     +   + ++   +      T  PV A
Sbjct: 26  LTALAPMQDVTNLWFMKVIAHYGSPDYFFTEYFRVNDTSRLNRGILSAITENDTGRPVFA 85

Query: 80  QFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLR 138
           Q    +  D V  +K +  Y + GVDLN GCP     +   G  LL  P  +  I++ LR
Sbjct: 86  QMIGESIPDLVRTAKELCGYNIAGVDLNMGCPAPRIYRKNVGGGLLLSPAKVEQILEELR 145

Query: 139 NVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS--SGPVDINGLKE 196
             + N   ++VK+R+  +   T      +       L S+     K    G V  + + E
Sbjct: 146 QAV-NDRPLTVKMRVGFENTDTFYEILDIVNRHNIDLLSLHGRTVKDMYHGAVKYDLIAE 204

Query: 197 VREALSVPMVANGGVKHLNDATTYMK 222
               +  P++ANG   +++ ATT ++
Sbjct: 205 AVRRVDCPVLANG---NIHSATTALE 227


>UniRef50_Q6MAU6 Cluster: Putative uncharacterized protein yohI;
           n=1; Candidatus Protochlamydia amoebophila UWE25|Rep:
           Putative uncharacterized protein yohI - Protochlamydia
           amoebophila (strain UWE25)
          Length = 326

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 39/164 (23%), Positives = 70/164 (42%), Gaps = 10/164 (6%)

Query: 65  ANEFMTTTT-DFPVIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCS 122
           AN +    T   P  AQ   ++ +   + ++ V       +DLNCGCP       G G S
Sbjct: 57  ANRYEANETFPIPQAAQLMGSDPELMAEMARAVERRGAQRIDLNCGCPSNTVTGRGAGSS 116

Query: 123 LLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQL---EKCGVTFLTSME 179
           LL +P+ +Y + K +   +    ++ V  +L +    T +    L   +  G+ +LT   
Sbjct: 117 LLKEPDHLYKVAKSMVEAV----NVPVTAKLRSGFTDTSLFHDNLLAAQASGIKYLTLHP 172

Query: 180 EHCTKSSG-PVDINGLKEVREALSVPMVANGGVKHLNDATTYMK 222
                  G P     + + ++ L +P+V NG +  + DA   +K
Sbjct: 173 RTKVDGYGPPAKWELIAQAKQLLKIPVVGNGDILTVQDALNMLK 216


>UniRef50_Q4FLD8 Cluster: Putative uncharacterized protein; n=2;
           Candidatus Pelagibacter ubique|Rep: Putative
           uncharacterized protein - Pelagibacter ubique
          Length = 330

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 31/131 (23%), Positives = 69/131 (52%), Gaps = 6/131 (4%)

Query: 25  APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           APM+  +  H R  +R  + + L ++ M+++++  +  K +  EF     + P+  Q   
Sbjct: 8   APMMDCTDRHERFFLRLISKNTLLYSEMVVSEAIHRGDKKKLLEF--NINEKPIALQIGG 65

Query: 84  NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
           ++     +A+K+   +  D ++LN GCP K   K+ +G  L+ +P ++ D +  +++V  
Sbjct: 66  SSPTLLAEATKVGEDFGYDEINLNLGCPSKKVEKNKFGACLMKEPNLVADCLSKMQSV-- 123

Query: 143 NKFSISVKIRL 153
            K  +++K R+
Sbjct: 124 TKLPVTIKTRI 134


>UniRef50_Q30WR3 Cluster: Dihydrouridine synthase family protein;
           n=3; Desulfovibrio|Rep: Dihydrouridine synthase family
           protein - Desulfovibrio desulfuricans (strain G20)
          Length = 376

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 47/203 (23%), Positives = 85/203 (41%), Gaps = 6/203 (2%)

Query: 25  APMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQNSKARANEFMTTTTDFPVIA--QF 81
           APM     + +R ++ +F    L FT M  A +    + AR+  F     + P +    F
Sbjct: 62  APMAGLGHIAYRQVLESFGGCGLVFTGMCSARAVPTENPARSPVFSWRPEELPALVCQLF 121

Query: 82  AANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141
            A+ +D    A ++      GVD+N GC     +K G G  LL  PE    +V  +R  +
Sbjct: 122 GADPQDMAAAARRVESEGFFGVDINMGCSVAPIVKKGCGADLLRDPERAVRMVDAVRRAV 181

Query: 142 PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHC--TKSSGPVDINGLKEVRE 199
                + ++     D +  V L ++L+  G   L          ++  P   + +  V++
Sbjct: 182 SVPVFVKMRTGWSPDPEPAVNLARRLQDAGADALVFHPRVAPDRRTHRPRTAH-IGLVKD 240

Query: 200 ALSVPMVANGGVKHLNDATTYMK 222
           A+ +P++ NG V    D    ++
Sbjct: 241 AVDIPVIGNGDVFDAADCAAMLE 263


>UniRef50_A6NW05 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides capillosus ATCC 29799|Rep: Putative
           uncharacterized protein - Bacteroides capillosus ATCC
           29799
          Length = 307

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 44/190 (23%), Positives = 81/190 (42%), Gaps = 6/190 (3%)

Query: 27  MVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAANNR 86
           M   + + FRT+ R   A    T M+ A + C   K           + P  AQ   ++ 
Sbjct: 1   MAGVTDMAFRTICRELGAGYTITEMVSAKALCYQDKKSIPLLKLGEGEHPCAAQIFGSDE 60

Query: 87  DDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNK 144
               +A+ +       D +D+N GCP       G G  L+   +    + + +      +
Sbjct: 61  KCMEEAAAIAGEVSGADIIDINMGCPVPKVANSGDGSGLMRDVDKAVRVAEAVVRGAGER 120

Query: 145 FSISVKIRLLNDIKKT--VILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVREAL 201
             ++VK RL  D      V   + +E  GV+ +       T+  +G  + + ++EV++A+
Sbjct: 121 -PVTVKFRLGWDKGSINCVEFAKAMEAAGVSAVAVHGRTRTQMYAGTANWDYIREVKQAV 179

Query: 202 SVPMVANGGV 211
           S+P++ANG V
Sbjct: 180 SIPVIANGDV 189


>UniRef50_A6GHV6 Cluster: Dihydrouridine synthase family protein;
           n=1; Plesiocystis pacifica SIR-1|Rep: Dihydrouridine
           synthase family protein - Plesiocystis pacifica SIR-1
          Length = 321

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 2/110 (1%)

Query: 102 GVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRL-LNDIKKT 160
           G+DLN GCP K       G +LL  P  +  + + +R  +P +  ++VKIR+   D    
Sbjct: 88  GIDLNFGCPAKTVNSSDGGATLLKDPCRVEAVTRAVRAAVPAELPVTVKIRVGWEDPSPV 147

Query: 161 VILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREALSVPMVANG 209
           V + +  E  G ++LT            PVD   +   + A+S+ +VANG
Sbjct: 148 VEIARAAEAGGASWLTIHGRTRRQLYKPPVDYEAIGRAQAAVSMAVVANG 197


>UniRef50_Q5CRK5 Cluster: Ylr401cp-like protein with 2 CCCH domains
           plus Dus1p tRNA dihydrouridine synthase Tim barrel; n=2;
           Cryptosporidium|Rep: Ylr401cp-like protein with 2 CCCH
           domains plus Dus1p tRNA dihydrouridine synthase Tim
           barrel - Cryptosporidium parvum Iowa II
          Length = 707

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 31/133 (23%), Positives = 58/133 (43%), Gaps = 3/133 (2%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           + AP+     + FR L   F AD+  + M+L +       +       +  +     Q A
Sbjct: 319 ILAPLTTVGNLPFRRLCLKFGADVTVSEMVLCNEILSGKASELALLKKSPEEKYFGIQLA 378

Query: 83  ANNRDDFVDASKLVYPYV--DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140
             N+   +   + +  +   D +D+N  CP K     G G  L+ +   +  +VKGL+ V
Sbjct: 379 GGNKSTIIKTGEFINEHCEFDFIDINAACPLKSLHDKGAGSILVDRVSELETMVKGLKKV 438

Query: 141 LPNKFSISVKIRL 153
           +  K  ++VK+R+
Sbjct: 439 MDGKL-VTVKVRM 450


>UniRef50_A7S213 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 570

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 54/217 (24%), Positives = 96/217 (44%), Gaps = 19/217 (8%)

Query: 17  NKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP 76
           +K YL   AP+     + FR + + + AD+    M +  +  Q  ++        +++  
Sbjct: 218 DKLYL---APLTTIGNLPFRRICKQYGADITCGEMAMCTNLLQGQQSEWALVKRHSSEDI 274

Query: 77  VIAQFAANNRDDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134
              Q      D     ++L+     VD +D+N GCP       G G +L+ +   +  IV
Sbjct: 275 FGVQLCGAFPDTMTKCAELLQKETDVDFIDINTGCPIDLVFNKGAGSALMERKGKLQQIV 334

Query: 135 KGLRNVLPNKFSISVKIRL-LNDIKKT---VILCQQLEKCGVTFLT----SMEEHCTKSS 186
           +G+++V+     ++VKIR  ++D K T     L   L   G   +T    S E+  TKS+
Sbjct: 335 QGMKSVI--DIPLTVKIRAGIHDKKYTWNAHKLVGNLRDWGTDMVTIHGRSREQRYTKSA 392

Query: 187 GPVDINGLKEVREALS-VPMVANGGVKHLNDATTYMK 222
              D + + EV +  S +P+  NG +    DA  + K
Sbjct: 393 ---DWDYISEVAKLASPMPVFGNGDILSFEDAMQHRK 426


>UniRef50_O83945 Cluster: Probable tRNA-dihydrouridine synthase;
           n=2; Treponema|Rep: Probable tRNA-dihydrouridine
           synthase - Treponema pallidum
          Length = 340

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 31/133 (23%), Positives = 61/133 (45%), Gaps = 5/133 (3%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           AP+  YS   FR++   + A   +T M+ +++  ++S          + +     Q   +
Sbjct: 24  APVAGYSDSAFRSIAIEWEASFTYTEMVSSEAMVRDSLNTKRLIRRASNETHYAIQIFGS 83

Query: 85  NRDDFVDASKLVYPYVDG--VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL- 141
           N     + +KL+        +D+N GCP     K G G +L  +P  +Y++VK + + + 
Sbjct: 84  NPAVMAETAKLIVDSAQPSCIDINAGCPMPKITKTGAGAALTREPTRLYEVVKAVADAVY 143

Query: 142 --PNKFSISVKIR 152
               +  ++VKIR
Sbjct: 144 AQDARIPVTVKIR 156


>UniRef50_Q6MRF1 Cluster: Transcription regulator homolog yacF; n=1;
           Bdellovibrio bacteriovorus|Rep: Transcription regulator
           homolog yacF - Bdellovibrio bacteriovorus
          Length = 337

 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 45/198 (22%), Positives = 84/198 (42%), Gaps = 6/198 (3%)

Query: 18  KTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPV 77
           KT   V APM   +   FRT ++  +A +  T ++ A      S           +  P+
Sbjct: 8   KTNPFVLAPMAGITDHAFRTFIKKLDASVVVTELVSASGIEYKSDRTLKLMSFDESQRPI 67

Query: 78  IAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136
             Q      +    A+++      D VDLN GCP    +K G G ++L  P  +  +V  
Sbjct: 68  GIQLFGEEPEIVARAAQVAEADGCDFVDLNFGCPVPKVVKKGAGSAILKDPAAVQKMVST 127

Query: 137 LRNVLPNKFSISVKIRLLNDI--KKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDING 193
           ++  +  K  +++KIR   D   +    +C      GV+++        +S +G  D + 
Sbjct: 128 VKAAI--KIPLTIKIRTGWDANSRNATEICNIAYNEGVSWVAIHGRTRAQSYTGLADWDF 185

Query: 194 LKEVREALSVPMVANGGV 211
           + +V+    +P++ NG +
Sbjct: 186 IADVKANTKIPILGNGDI 203


>UniRef50_Q3E0H8 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=5; Chloroflexi (class)|Rep: Dihydrouridine
           synthase TIM-barrel protein nifR3 - Chloroflexus
           aurantiacus J-10-fl
          Length = 407

 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 47/220 (21%), Positives = 93/220 (42%), Gaps = 3/220 (1%)

Query: 1   MKEICDIMEKFADAKINKTYLKVCAPMVRYSKVHFRTLV-RNFNADLCFTPMILADSFCQ 59
           ++EI  +   +  A I      + APM   +   FR ++ R     L  T M  A S   
Sbjct: 64  LEEIARLPTSYQVAHIRIEPNIILAPMAGVTDSIFRRMILRLGGCGLVSTEMTNAASVSP 123

Query: 60  NSKARANEFMTTTTDFPVIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDG 118
            +  R         + P+  Q + N+ D   +A+++V     D +D+NCGCP       G
Sbjct: 124 KALRRHRLLDYLPEERPLTMQISGNDPDLVANAARVVEQLGADIIDINCGCPSPKVTGGG 183

Query: 119 YGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM 178
           +G +LL     +  +++ +R  +    ++  +          +   ++ E  GV+ L   
Sbjct: 184 HGSALLRDLPKMERLLRAVREAVQIPVTLKFRAGWDEQSLNFIEAGKRAEAAGVSALALH 243

Query: 179 EEHCTKS-SGPVDINGLKEVREALSVPMVANGGVKHLNDA 217
                +   G  D + +  +++A+S+P++ +G V   +DA
Sbjct: 244 PRTREQGYKGQADWSRVAALKQAVSIPVIGSGDVTSAHDA 283


>UniRef50_Q884C6 Cluster: tRNA-dihydrouridine synthase C; n=8;
           Proteobacteria|Rep: tRNA-dihydrouridine synthase C -
           Pseudomonas syringae pv. tomato
          Length = 317

 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 33/117 (28%), Positives = 55/117 (47%), Gaps = 4/117 (3%)

Query: 103 VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVI 162
           +DLN GCP K   +   G  LL +PE+++ IV  +R  +P    ++ K+RL  +     +
Sbjct: 92  LDLNFGCPAKTVNRSRGGAILLKEPELLHTIVSQVRRAVPKDIPVTAKMRLGYENTDGAL 151

Query: 163 LCQQLEKCGVTFLTSMEEHCTKSSG---PVDINGLKEVREALSVPMVANGGVKHLND 216
            C +    G      +    TK  G   P     +  ++E + VP+VANG +  + D
Sbjct: 152 DCARALADGGAAQIVVHAR-TKVDGYKPPAHWEWIARIQEVVKVPVVANGEIWTVED 207


>UniRef50_Q489F6 Cluster: NifR3/Smm1 family protein; n=2;
           Proteobacteria|Rep: NifR3/Smm1 family protein -
           Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
           (Vibriopsychroerythus)
          Length = 338

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 42/189 (22%), Positives = 80/189 (42%), Gaps = 2/189 (1%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           APM   +   FR L     A L  + M+ ++    N++      +          Q A +
Sbjct: 15  APMAGITDQPFRQLCCQLGAGLAVSEMLSSNPKVWNTEKSKLRMLHGDAAGIRSVQIAGS 74

Query: 85  NRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143
             D+   A+K+        +D+N GCP K   K   G +LL +P  +  IV+ + N +  
Sbjct: 75  CPDELAFAAKVNADNGAQIIDINMGCPAKKVNKKLAGSALLREPAQVERIVQSVVNAVDI 134

Query: 144 KFSISVKIRLLNDIKKTVILCQQLEKCGVTFL-TSMEEHCTKSSGPVDINGLKEVREALS 202
             ++ ++     D +  + + +  E  G+  L            G  + + +K ++ A+S
Sbjct: 135 PVTLKIRTGWCEDTRNGIEIAKIAENSGIASLAVHGRTRNDFYKGNAEYDTIKAIKLAIS 194

Query: 203 VPMVANGGV 211
           +P+VANG +
Sbjct: 195 IPVVANGDI 203


>UniRef50_Q1N033 Cluster: Putative uncharacterized protein; n=1;
           Oceanobacter sp. RED65|Rep: Putative uncharacterized
           protein - Oceanobacter sp. RED65
          Length = 321

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 51/204 (25%), Positives = 86/204 (42%), Gaps = 14/204 (6%)

Query: 25  APMVRYSKVHFRTLV-RNFNADLCFTPMI------LADSFCQNSKARANEFMTTTTDFPV 77
           APM     VH RTL+ R    D C T  +      L +   +     ++    T    PV
Sbjct: 6   APMEGLVDVHMRTLLTRGGYFDYCVTEFLRVTTQLLPERSFRRICPESDHQWKTPAGTPV 65

Query: 78  IAQFAANNRDDFVD-ASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136
             Q   ++     + A +        V++N GCP ++      G  LL  P+ I+ I++ 
Sbjct: 66  HLQLLGSDPVAMAENACRAAELGAPVVNINFGCPSRFVNGRCGGAYLLQFPDQIHTILES 125

Query: 137 LRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSG---PVDIN 192
           +R  LP    ++ K+RL   D    +   Q +E  GV  +       TK  G   P   +
Sbjct: 126 VRKALPEHVPLTAKMRLGFKDDALALANAQAMESAGVRDICIHAR--TKVQGYRPPAHWH 183

Query: 193 GLKEVREALSVPMVANGGVKHLND 216
            +K +++ + VP++ANG + +  D
Sbjct: 184 QIKNIKQQVKVPIIANGEIWNRRD 207


>UniRef50_Q056Y8 Cluster: TRNA-dihydrouridine synthase A; n=1;
           Buchnera aphidicola str. Cc (Cinara cedri)|Rep:
           TRNA-dihydrouridine synthase A - Buchnera aphidicola
           subsp. Cinara cedri
          Length = 348

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 40/148 (27%), Positives = 64/148 (43%), Gaps = 8/148 (5%)

Query: 10  KFADAKINKTYLKV--CAPMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARAN 66
           K  + K+ K Y      APM +Y+  H     R        +T MI       + K    
Sbjct: 17  KINNIKMKKKYSNKFSVAPMFKYTDQHCLYFYRQLTKKTFLYTEMITIQKMLFSKKLFKK 76

Query: 67  EFMTTTTDFPVIAQFAANNRDDF-VDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLS 125
           + +      P+  Q A NN     + A K  +     ++LN GCP K A    +G  L++
Sbjct: 77  KQIKKNN--PIAIQLAGNNPLFLSLCAKKAYFLGFKEINLNIGCPSKKAKSGNFGIYLMN 134

Query: 126 KPEIIYDIVKGLRNVLPNKFSISVKIRL 153
            P ++Y+++K +   +P    IS+KIRL
Sbjct: 135 NPILVYNLIKAIYLTVP--IQISIKIRL 160


>UniRef50_A1RNI1 Cluster: TIM-barrel protein, yjbN family; n=30;
           Bacteria|Rep: TIM-barrel protein, yjbN family -
           Shewanella sp. (strain W3-18-1)
          Length = 343

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 31/129 (24%), Positives = 58/129 (44%), Gaps = 5/129 (3%)

Query: 25  APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           APM+ ++  H+R   R  +A  L +T M+   +       R +       + P+  Q   
Sbjct: 28  APMLDWTDRHYRYFARLMSAKALLYTEMVTTGAILHG---RGDYLAYNQEEHPLALQLGG 84

Query: 84  NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
           +N  D    +KL      D V+LN GCP        +G  L+++PE++ + V  ++ V+ 
Sbjct: 85  SNPQDLARCAKLAAERGYDEVNLNVGCPSDRVQNGRFGACLMAEPELVAECVDAMKQVVD 144

Query: 143 NKFSISVKI 151
              ++  +I
Sbjct: 145 IPVTVKTRI 153


>UniRef50_A3LUK5 Cluster: Dihydrouridine synthase of tRNA; n=6;
           Saccharomycetales|Rep: Dihydrouridine synthase of tRNA -
           Pichia stipitis (Yeast)
          Length = 613

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 37/152 (24%), Positives = 70/152 (46%), Gaps = 6/152 (3%)

Query: 6   DIMEKFADAK-INKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKAR 64
           D   K A+ K ++    K+ +P+     + +R L++   AD+ ++ M L+    Q + A 
Sbjct: 229 DAPYKIAEKKRLDFRNAKIVSPLTTVGNLPYRRLMKKLGADITYSEMALSVPLLQATNAE 288

Query: 65  ANEFMTTTTDFPVIA-QFAANNRDDFVDASKLVY---PYVDGVDLNCGCPQKWAMKDGYG 120
                   T++P    Q A +        ++++     +V  ++LNCGCP     + G G
Sbjct: 289 WALPKAHRTEYPGYGVQIATSKHWAAAKVAEIISRETEHVSELNLNCGCPIDLLYRQGQG 348

Query: 121 CSLLSKPEIIYDIVKGLRNVLPNKFSISVKIR 152
            +LL +P  +  I+K + N       ++VKIR
Sbjct: 349 SALLEQPARLVRILKAM-NASSGDIPVTVKIR 379


>UniRef50_UPI0000499494 Cluster: conserved hypothetical protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
           hypothetical protein - Entamoeba histolytica HM-1:IMSS
          Length = 515

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 41/191 (21%), Positives = 82/191 (42%), Gaps = 7/191 (3%)

Query: 30  YSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAANNRDDF 89
           +  + FR +V+ F  D+  T MI+A+S  +   +        +++     Q    N    
Sbjct: 180 FGNLPFRKVVKRFGCDVTMTEMIMAESLVEGKTSEWALVKRDSSEDIFGIQLCVGNSMLA 239

Query: 90  VDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSIS 148
             A +++     D  +LNC CP  +  K G G  L+ +P+ I  ++  +R+V     +I 
Sbjct: 240 AKACQVLNSVDCDFYELNCACPIDYVYKKGMGAQLIERPKRIESLLHAMRSVTERPVAIK 299

Query: 149 VKIRLLNDIKKTVIL--CQQLEKCGVTFL-TSMEEHCTKSSGPVDINGLKEVREALSVPM 205
           V+    ++  + V+L  C       V+    + ++  TKS+   D + +K+       P+
Sbjct: 300 VRTGKSSNTIQDVLLPNCADYGAAMVSIHGRTRDQRYTKSA---DWDFIKQATTITQCPV 356

Query: 206 VANGGVKHLND 216
           +  G +    D
Sbjct: 357 IGVGDIYGYKD 367


>UniRef50_Q012U0 Cluster: Nitrogen regulation family protein; n=2;
           Ostreococcus|Rep: Nitrogen regulation family protein -
           Ostreococcus tauri
          Length = 490

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 34/152 (22%), Positives = 73/152 (48%), Gaps = 9/152 (5%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPV-----IA 79
           APM+ Y+  HFR + R  +A       +  D    ++       +    D+PV     + 
Sbjct: 105 APMMEYTTAHFRVMCRLMSAKTWLWTEMEVDQTLTHAVLEGTR-VDRFLDYPVETAATVL 163

Query: 80  QFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQ-KWAMKDGYGCSLLSKPEIIYDIVKGL 137
           Q   ++ +    A+ +  PY  + ++LN GCP  K A K  +G +L+++P ++ + ++ +
Sbjct: 164 QLGGSDPEILGRATAIAAPYGYEEINLNSGCPSPKVAGKGCFGAALMTEPRLVAECLQAM 223

Query: 138 RNVLPNKFSISVKIRL-LNDIKKTVILCQQLE 168
               P+   +S+K R+ +++      LC+ ++
Sbjct: 224 NENAPSGTPVSIKCRIGVDECDSYDALCEYVD 255


>UniRef50_A7HK00 Cluster: Dihydrouridine synthase DuS; n=4;
           Thermotogaceae|Rep: Dihydrouridine synthase DuS -
           Fervidobacterium nodosum Rt17-B1
          Length = 322

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 38/127 (29%), Positives = 55/127 (43%), Gaps = 1/127 (0%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           APM   +   FR L     A   FT MI A S   N K     F        V  Q   +
Sbjct: 14  APMAGVTDYPFRKLCLQHGAYFAFTEMISAKSVIINVKINEIYFPRQDEKDRVGVQLFGS 73

Query: 85  NRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNK 144
           +  +  +A+ +V      VDLN GCP    +K G G +LL        +V+ +R+VL  +
Sbjct: 74  DYAELSEAAAIVQEKGLWVDLNAGCPVSKVIKKGAGSALLKDLGEFRKVVRAMRSVL-KR 132

Query: 145 FSISVKI 151
           F++  +I
Sbjct: 133 FTVKTRI 139


>UniRef50_A4BCJ5 Cluster: NifR3/Smm1 family protein; n=2;
           Gammaproteobacteria|Rep: NifR3/Smm1 family protein -
           Reinekea sp. MED297
          Length = 314

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 23/52 (44%), Positives = 33/52 (63%)

Query: 102 GVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRL 153
           G+DLN GCP K       G  LL++PE IY +V+ +R+ LP   ++S K+RL
Sbjct: 91  GLDLNFGCPSKTVNASKGGAVLLTEPESIYAVVRSVRDALPGDQTLSAKMRL 142


>UniRef50_A4AAB0 Cluster: TRNA-dihydrouridine synthase C; n=2;
           unclassified Gammaproteobacteria|Rep:
           TRNA-dihydrouridine synthase C - Congregibacter
           litoralis KT71
          Length = 328

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 41/152 (26%), Positives = 67/152 (44%), Gaps = 7/152 (4%)

Query: 71  TTTDFPVIAQFAANNRDDFVD-ASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129
           T++  PV  Q    +     + AS+       GVDLN GCP K   +   G  +L +PE 
Sbjct: 65  TSSGVPVYLQILGGDPSVVAENASRAAELGAPGVDLNFGCPAKTVNRSDGGSIILREPER 124

Query: 130 IYDIVKGLRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHCTKSSG- 187
           ++ IV   R  LP    +SVKIRL  +   + + +   ++    + L       T++ G 
Sbjct: 125 VHRIVAATRQALPPSVPLSVKIRLGFDSSDRFLDIVSGIDAARPSELVIHAR--TRADGY 182

Query: 188 --PVDINGLKEVREALSVPMVANGGVKHLNDA 217
             P     +   R    +P++ANG +  + DA
Sbjct: 183 RPPAYWEHIALARSKTRLPLIANGEIWGVGDA 214


>UniRef50_UPI0000E472BC Cluster: PREDICTED: similar to
           tRNA-dihydrouridine synthase; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to
           tRNA-dihydrouridine synthase - Strongylocentrotus
           purpuratus
          Length = 499

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 39/146 (26%), Positives = 68/146 (46%), Gaps = 17/146 (11%)

Query: 7   IMEKFADAKINKTYLKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARAN 66
           + E +  ++++     + APMVR   +  R L   + AD+ +   ++ D      +   N
Sbjct: 27  VPEIWMSSRLSYANKVILAPMVRIGTLPTRLLALEYGADIVYCQELI-DFKMLTCRRHVN 85

Query: 67  EFMTT----TTDFPVIAQFAANNRDDFV------DA------SKLVYPYVDGVDLNCGCP 110
             + T    + D  VI +  +   D  V      DA      +K+V   V G+D+N GCP
Sbjct: 86  RVLGTVDYISKDDVVIFRTCSKETDRLVFQMGTADAQRALRVAKMVEKDVSGIDINMGCP 145

Query: 111 QKWAMKDGYGCSLLSKPEIIYDIVKG 136
           + +++K G G +LL KP+ I +I  G
Sbjct: 146 KDFSLKGGMGAALLQKPDTIKEIPSG 171


>UniRef50_Q2UL89 Cluster: Uncharacterized conserved protein; n=15;
           Pezizomycotina|Rep: Uncharacterized conserved protein -
           Aspergillus oryzae
          Length = 730

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 28/83 (33%), Positives = 45/83 (54%), Gaps = 4/83 (4%)

Query: 74  DFPVIAQFAANNRDDFVDASKLVYPYVDG---VDLNCGCPQKWAMKDGYGCSLLSKPEII 130
           DF   AQ AAN     + A++++  Y      +DLNCGCP     ++G G +LL  P  +
Sbjct: 394 DFRFGAQIAANKHWQALKATEVLSAYTPNLRVIDLNCGCPIDLLFREGAGSALLEHPSKL 453

Query: 131 YDIVKGLRNVLPNKFSISVKIRL 153
             I++G+ N +  +  I+ KIR+
Sbjct: 454 ERILRGM-NAVSQEIPITAKIRM 475


>UniRef50_A6DU09 Cluster: Dihydrouridine synthase family protein;
           n=1; Lentisphaera araneosa HTCC2155|Rep: Dihydrouridine
           synthase family protein - Lentisphaera araneosa HTCC2155
          Length = 334

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 35/79 (44%), Positives = 45/79 (56%), Gaps = 6/79 (7%)

Query: 77  VIAQFAANNRDDFVDA-SKLVYPYV-DGVDLNCGCPQKWAMKDGYGCS-LLSKPEIIYDI 133
           ++AQ    N D F +A SK V P V DGVD+N GCP    +K G GCS L++ PEI  ++
Sbjct: 82  IVAQVWGKNPDKFSEAISKYVDPEVFDGVDINMGCPVAKIVKQG-GCSALINTPEIAKEL 140

Query: 134 VKGLRNVLPNKFSISVKIR 152
           V  L      K  +SVK R
Sbjct: 141 V--LAAKAATKLPVSVKTR 157


>UniRef50_Q89LQ7 Cluster: Nitrogen regulation protein; n=22;
           Alphaproteobacteria|Rep: Nitrogen regulation protein -
           Bradyrhizobium japonicum
          Length = 371

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 43/191 (22%), Positives = 78/191 (40%), Gaps = 7/191 (3%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           APM   +    R LV    A L  + M  +D    N    +      T   P + Q A  
Sbjct: 53  APMSGVTDSPVRRLVAELGAGLVVSEMTASDELA-NGHRMSRLRCEATGIGPHVVQLAGC 111

Query: 85  NRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143
                 + +++      D +D+N GCP +       G +L+   +    ++     +   
Sbjct: 112 EAHWMAEGARIAEAEGADIIDINMGCPARHVTGGQSGSALMRDLDHAVGLIDA--TIAAV 169

Query: 144 KFSISVKIRLLND--IKKTVILCQQLEKCGVTFLTSM-EEHCTKSSGPVDINGLKEVREA 200
           K  +++K+RL  D   +    L ++ E  G+  +T      C    G  D + ++ VREA
Sbjct: 170 KVPVTLKMRLGWDDRSRNAPELARRAEAAGIKLVTVHGRTRCQFYKGEADWDAIRTVREA 229

Query: 201 LSVPMVANGGV 211
           +S+P++ NG +
Sbjct: 230 ISIPLIVNGDI 240


>UniRef50_O51243 Cluster: Putative uncharacterized protein BB0225;
           n=3; Borrelia burgdorferi group|Rep: Putative
           uncharacterized protein BB0225 - Borrelia burgdorferi
           (Lyme disease spirochete)
          Length = 335

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 38/132 (28%), Positives = 63/132 (47%), Gaps = 7/132 (5%)

Query: 25  APMVRYSKVHFRTLVRNFNADLC-FTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           APMV  +  HFR L+R  +  +  +TPMI A S       +  +      + P+  Q A 
Sbjct: 10  APMVNITDEHFRYLIRLLSKKVTLYTPMISAKSIIMGDVKKIVK--QNPLESPIAIQIAT 67

Query: 84  NNRDDFVDASKLVYPYV--DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141
           N+++D + A +++  +   D  +LN GCP         G  L+     + +I+K ++   
Sbjct: 68  NSKNDALKAIQILEKHFNFDEYNLNVGCPSLKIQNANCGACLMGNANQVGEILKTMKE-N 126

Query: 142 PNKFSISVKIRL 153
            NK  IS+K RL
Sbjct: 127 TNK-PISIKHRL 137


>UniRef50_Q1JWD3 Cluster: Dihydrouridine synthase, DuS; n=1;
           Desulfuromonas acetoxidans DSM 684|Rep: Dihydrouridine
           synthase, DuS - Desulfuromonas acetoxidans DSM 684
          Length = 320

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 39/146 (26%), Positives = 66/146 (45%), Gaps = 5/146 (3%)

Query: 67  EFMTTTTDFPVIAQFAANNRDDFVDASKLVYPYVDG-VDLNCGCPQKWAMKDGYGCSLLS 125
           E +    D P++ Q   +  +   +A+++V       V+LN GCP         G ++L 
Sbjct: 61  EILAGVDDVPLVVQLIGHRSESLAEAAQIVADLGGAHVNLNMGCPFGRTTTGKTGGAMLQ 120

Query: 126 KPEIIYDIVKGLRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVTFLTSMEEHCT- 183
           +PE I D ++ +R       S+SVK+R   +D ++   L    EK GV F+         
Sbjct: 121 EPEKIGDCLRAIRAAFHG--SVSVKVRAGYDDPEQIFDLLPVFEKYGVDFIVLHPRTVVQ 178

Query: 184 KSSGPVDINGLKEVREALSVPMVANG 209
           K +   D      V  A ++P++ANG
Sbjct: 179 KYADDADHAVTARVVAATALPVIANG 204


>UniRef50_Q9V0Y6 Cluster: Dihydroorotate dehydrogenase; n=8;
           Euryarchaeota|Rep: Dihydroorotate dehydrogenase -
           Pyrococcus abyssi
          Length = 303

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 39/178 (21%), Positives = 79/178 (44%), Gaps = 23/178 (12%)

Query: 62  KARANEFMTTTTDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGC 121
           +A   EF     DFPVI        ++F   ++ +    D  +LN  CP       GYG 
Sbjct: 81  EAFLEEFRKEKFDFPVIVSIFGGTPEEFAFLAEKLGEVADAFELNLSCPH----AKGYGM 136

Query: 122 SLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEH 181
            +  KPE +Y++VK +++V  +K  I+     ++DI++  +  ++    GV+ + +++  
Sbjct: 137 EIGQKPENVYEVVKAVKDV-TDKPVIAKLTPNVSDIRELGLAAEKAGADGVSAINTVKAI 195

Query: 182 C-----------TKSSG-------PVDINGLKEVREALSVPMVANGGVKHLNDATTYM 221
                        K  G       P+ +  + ++  +L +P++  GG+    DA  ++
Sbjct: 196 AIDIYAKRPILSNKFGGYSGPGVKPIALRAVYDLASSLDIPVIGIGGITTWQDAVEFL 253


>UniRef50_Q7UXK8 Cluster: Putative uncharacterized protein; n=3;
           Planctomycetaceae|Rep: Putative uncharacterized protein
           - Rhodopirellula baltica
          Length = 374

 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 36/133 (27%), Positives = 58/133 (43%), Gaps = 3/133 (2%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTD--FPVIAQ 80
           V A +  YS +  R + R  +A      ++L       +K           D   PV  Q
Sbjct: 41  VQAALSGYSDLPMRVIARRHSASYTICEVMLDQFLLSLTKREKTRHFLDIADEEHPVGGQ 100

Query: 81  FAANNRDDF-VDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139
                 + F   A KLV    D +D+N GCP K  +    G   LS+P +  +I++  R+
Sbjct: 101 LMGAEPEQFSAGALKLVEAGFDVIDVNFGCPVKKVLGRCRGGFHLSQPAVAIEILRRTRD 160

Query: 140 VLPNKFSISVKIR 152
           V+P+   ++VK+R
Sbjct: 161 VVPDHIPVTVKMR 173


>UniRef50_Q6M9N8 Cluster: Putative uncharacterized protein; n=1;
           Candidatus Protochlamydia amoebophila UWE25|Rep:
           Putative uncharacterized protein - Protochlamydia
           amoebophila (strain UWE25)
          Length = 297

 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 7/141 (4%)

Query: 76  PVIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134
           P+  Q   +       A+K++     D VDLNCGCP     KDG G  LL  PE+I +IV
Sbjct: 26  PIGGQLCGSKPSIAGQAAKIIEELGFDIVDLNCGCPVDKITKDGSGSGLLKTPELIGEIV 85

Query: 135 KGLRNVLPNKFSISVKIRLLNDIKKTVI--LCQQLEKCGVTFLTSMEEHCTKS-SGPVDI 191
             + + +  K  ++VKIR   D ++  +  + Q +E+ G   +        +   GP + 
Sbjct: 86  CNMVSAV--KIPVTVKIRAGWDEQQIQVENIVQIVEQAGAQAICIHGRTRQQGYRGPANW 143

Query: 192 NGLKEVR-EALSVPMVANGGV 211
             +K  +  A S+ ++ NG V
Sbjct: 144 EYIKRGKLAAKSIKIIGNGDV 164


>UniRef50_A6EDJ3 Cluster: Probable TIM-barrel protein, NifR3 family;
           n=1; Pedobacter sp. BAL39|Rep: Probable TIM-barrel
           protein, NifR3 family - Pedobacter sp. BAL39
          Length = 335

 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 39/200 (19%), Positives = 84/200 (42%), Gaps = 4/200 (2%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           APM   S   FR + +    D+ +T  I ++   +++     +      + P+  Q   +
Sbjct: 18  APMEDVSDPPFRFVCKQSGVDMMYTEFISSEGLIRDAAKSRAKLDIFEYERPIGIQIFGS 77

Query: 85  NRDDFVDASKLV-YPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143
             D   +A+++      D +D+N GCP K     G G +LL   + + ++ K + N    
Sbjct: 78  EIDHMREATEIASMAGPDLMDINYGCPVKQVACRGAGSALLQDIDKMVEMTKAVVNATHL 137

Query: 144 KFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE--A 200
             ++  ++   ++ K    + ++L+  G+  LT           G  D   ++E++    
Sbjct: 138 PVTVKTRLGWDDNTKNVEEVAERLQDIGIQGLTIHGRTRAQMYKGEADWTLIREIKRNPR 197

Query: 201 LSVPMVANGGVKHLNDATTY 220
           + +P+  NG V  +  A  +
Sbjct: 198 IKIPIFGNGDVDSIQKAADW 217


>UniRef50_Q9FI41 Cluster: Emb|CAB87804.1; n=7; Magnoliophyta|Rep:
           Emb|CAB87804.1 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 387

 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 29/110 (26%), Positives = 54/110 (49%), Gaps = 5/110 (4%)

Query: 25  APMVRYSKVHFRTLVRNFNADL-CFTPMILADSFCQNSKARANEFMTTTTD-FPVIAQFA 82
           APM+ ++  H+RTL R        +T M+ A++         + F+  + D  P++ Q  
Sbjct: 15  APMMGWTDNHYRTLARLITKHAWLYTEMLAAETIVYQED-NLDSFLAFSPDQHPIVLQIG 73

Query: 83  ANNRDDFVDASKLVYPYV-DGVDLNCGCPQ-KWAMKDGYGCSLLSKPEII 130
             N ++   A++L   Y  D ++ NCGCP  K + +  +G  L+  P+ +
Sbjct: 74  GRNLENLAKATRLANAYAYDEINFNCGCPSPKVSGRGCFGALLMLDPKFV 123


>UniRef50_Q0F181 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=1; Mariprofundus ferrooxydans PV-1|Rep:
           Dihydrouridine synthase TIM-barrel protein nifR3 -
           Mariprofundus ferrooxydans PV-1
          Length = 341

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 38/191 (19%), Positives = 77/191 (40%), Gaps = 2/191 (1%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           V APM   + + FR + + F   L  T MI + +     +           + PV  Q A
Sbjct: 21  VLAPMAGITDLPFRRICKRFGVGLMVTEMIASRAVDMGRERTERMAELGDDEHPVSIQIA 80

Query: 83  ANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141
            ++ +   +A++    +  D VD+N GCP K   K   G ++L    ++  ++  +   +
Sbjct: 81  GSDPEFVTEAARWAVGHGADFVDINMGCPVKKICKQVAGSAMLRDEALVARVLAAVVAAV 140

Query: 142 PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREA 200
               ++ ++    +  K    + +  E  G+  LT           G      +   + A
Sbjct: 141 DVPVTLKIRTGWDDQSKNVQNIARIAEDSGIQLLTVHGRTRAQMFHGHACWEDIGLAKAA 200

Query: 201 LSVPMVANGGV 211
           +S+P++ NG +
Sbjct: 201 VSIPVIGNGDI 211


>UniRef50_Q04VP3 Cluster: TRNA-dihydrouridine synthase; n=4;
           Leptospira|Rep: TRNA-dihydrouridine synthase -
           Leptospira borgpetersenii serovar Hardjo-bovis (strain
           JB197)
          Length = 339

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 39/157 (24%), Positives = 71/157 (45%), Gaps = 7/157 (4%)

Query: 15  KINKTYLKVCAPMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTT 73
           KI K Y    APM+  +  HFR  +R  +     +T MI   +     + R   +  +  
Sbjct: 7   KIPKRYPVSLAPMMDRTDRHFRYFLRLISKHTFLYTEMIHTGAILHGDRRRFLSY--SPE 64

Query: 74  DFPVIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYD 132
           + P+  Q   +N     ++SK+   Y    ++LN GCP     +  +G  L+  PE + +
Sbjct: 65  ELPLAIQLGGDNPKALAESSKIGEDYGYSEINLNVGCPSDRVREGNFGACLMETPERVAE 124

Query: 133 IVKGLRNVLPNKFSISVKIRLLNDIKKTV-ILCQQLE 168
           +V  +   +     ++VK R+    K+T+  LC+ +E
Sbjct: 125 LVCAMDGNV--SIPVTVKCRIGISGKETLEDLCRFIE 159


>UniRef50_A5EVV4 Cluster: Dihydrouridine synthase; n=1;
           Dichelobacter nodosus VCS1703A|Rep: Dihydrouridine
           synthase - Dichelobacter nodosus (strain VCS1703A)
          Length = 318

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 44/192 (22%), Positives = 82/192 (42%), Gaps = 7/192 (3%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILA-DSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           APM   S + +R+L + F +      M+ A   F    +++          FP I Q   
Sbjct: 17  APMAGISDLPYRSLCQRFGSHYTIAEMVDARPQFLAMPESQLRLQFDDDARFPKIVQLVG 76

Query: 84  NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
            +     + ++++     D +D+N GCP K   K   G +LLS    +  I+  +  V+ 
Sbjct: 77  GDPYLMAETAQVMQALGCDVIDINMGCPAKKVGKQNAGSALLSDLPQVEKILAQVTRVV- 135

Query: 143 NKFSISVKIRL-LNDIKKTV-ILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE 199
               +++K RL  N+   T+  + +  E  GV  LT        + +G    + +  V+ 
Sbjct: 136 -SIPVTLKTRLGFNEQTMTIETVAKIAENTGVAALTVHGRTRAQRFNGTAHYDEIGRVKA 194

Query: 200 ALSVPMVANGGV 211
             S+P++ NG +
Sbjct: 195 QTSLPIIVNGDI 206


>UniRef50_A4TZK1 Cluster: Dihydrouridine synthase, DuS; n=4;
           Proteobacteria|Rep: Dihydrouridine synthase, DuS -
           Magnetospirillum gryphiswaldense
          Length = 335

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 38/198 (19%), Positives = 88/198 (44%), Gaps = 3/198 (1%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           + APM   + +  R LV+   A L  + MI + +  + ++           + P+  Q A
Sbjct: 21  ILAPMSGVTDMPCRRLVKRMGAGLVVSEMIASQAMIRANRQTMKMASNCAEEHPMSVQLA 80

Query: 83  ANNRDDFVDASKLVYPYVDGV-DLNCGCPQKWAMKDGYGCSLLSKPEIIY-DIVKGLRNV 140
               +   +A+++       + D+N GCP K     G   S L K EI+   +++     
Sbjct: 81  GCEPEVMAEAARMNADRGAAIIDINMGCPVKKVAVKGEAGSALMKDEILAGQLMEATVRA 140

Query: 141 LPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVRE 199
           +    ++  ++   ++      L +  ++ G+  +T       +  +G  D   +++V++
Sbjct: 141 VDVPVTLKCRMGWDHNRLNAPRLARIAQESGIKMVTIHGRTRQQFYTGTADWKFVRQVKD 200

Query: 200 ALSVPMVANGGVKHLNDA 217
           A+ +P++ NG ++ ++DA
Sbjct: 201 AVDIPVIVNGDIETIDDA 218


>UniRef50_A1AW94 Cluster: TIM-barrel protein, yjbN family; n=1;
           Candidatus Ruthia magnifica str. Cm (Calyptogena
           magnifica)|Rep: TIM-barrel protein, yjbN family - Ruthia
           magnifica subsp. Calyptogena magnifica
          Length = 322

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 27/133 (20%), Positives = 62/133 (46%), Gaps = 4/133 (3%)

Query: 25  APMVRYSKVHFRTLVRNFNADL-CFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           APM+ ++  H R   R  + ++  +T M+ A +    +K R  +F     + P++ Q   
Sbjct: 10  APMMDWTDRHCRYFYRLISKNVQLWTEMVTARAILYGNKNRLLDF--NVCEHPLVLQLGG 67

Query: 84  NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
           +   +   A+K+   +  + +++N GCP        +G  L+  P+++   V  +R ++ 
Sbjct: 68  SEPKEMAQAAKIAQDWGYNEININVGCPSNRVQSSNFGVCLMQTPQVVAQCVDAMRQMVD 127

Query: 143 NKFSISVKIRLLN 155
              ++  +I + N
Sbjct: 128 VPITVKSRIGVDN 140


>UniRef50_Q5HJT5 Cluster: Probable tRNA-dihydrouridine synthase;
           n=41; Bacilli|Rep: Probable tRNA-dihydrouridine synthase
           - Staphylococcus aureus (strain COL)
          Length = 328

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 36/135 (26%), Positives = 61/135 (45%), Gaps = 7/135 (5%)

Query: 23  VCAPMVRYSKVHFRTLVRNF-NADLCFTPMILADSFCQNSKARANEFMTTTTDF--PVIA 79
           + APM   + + FR +V      D+ FT     +SFC      +     T ++   P++A
Sbjct: 15  ILAPMEDVTDIVFRHVVSEAARPDVFFTEFTNTESFCHPEGIHSVRGRLTFSEDEQPMVA 74

Query: 80  QFAANNRDDFVDAS-KLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLR 138
               +  + F + S +L      G+DLN GCP     K G G  L+ +P++  +I++  +
Sbjct: 75  HIWGDKPEQFRETSIQLAKMGFKGIDLNMGCPVANVAKKGKGSGLILRPDVAAEIIQATK 134

Query: 139 NVLPNKFSISVKIRL 153
                   +SVK RL
Sbjct: 135 ---AGGLPVSVKTRL 146


>UniRef50_A1IF01 Cluster: Dihydrouridine synthase family protein;
           n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep:
           Dihydrouridine synthase family protein - Candidatus
           Desulfococcus oleovorans Hxd3
          Length = 326

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 38/197 (19%), Positives = 78/197 (39%), Gaps = 2/197 (1%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           + AP+   +   FR L +     L ++ M+ +      S+       TT  + P   Q  
Sbjct: 13  ILAPLAGITDAPFRRLAKAAGCALVYSEMVSSHGLFYQSEKTGAMLRTTPEEAPFAVQIF 72

Query: 83  ANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141
                    A+ +V       +D+N GC  K  +K G G +L+    +  ++++ +R+ +
Sbjct: 73  GGKPAVMGRAAAMVQASGAHMIDINFGCSVKKILKSGAGAALMKDLPLAAEVIQAVRDAV 132

Query: 142 PNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGLKEVREA 200
               +I ++     D      L +  E  GV  +       T+   G  D + +  +++ 
Sbjct: 133 SIPLTIKMRSGWNPDGSDAFHLAEIAEARGVNAVALHPRTATQGFGGTADWSLIAALKQR 192

Query: 201 LSVPMVANGGVKHLNDA 217
             +P++ NG +    DA
Sbjct: 193 TGLPVIGNGDIVLPEDA 209


>UniRef50_Q7X346 Cluster: Putative uncharacterized protein; n=1;
           uncultured Acidobacteria bacterium|Rep: Putative
           uncharacterized protein - uncultured Acidobacteria
           bacterium
          Length = 355

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 48/193 (24%), Positives = 80/193 (41%), Gaps = 13/193 (6%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFP----VIAQ 80
           APM + S + +R L     A +  + M LA    +  K + N        FP       Q
Sbjct: 2   APMTKGSNLPYRRLCVELGARITVSEMTLA----RRLKQKRNSEFALIRRFPGEPCFGVQ 57

Query: 81  FAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139
            A N  D+   A+ LV     D VD+N GCP  +  + G G S+  +P+ +  +V+ ++ 
Sbjct: 58  LAGNKPDETAWAAALVESRGADFVDINFGCPIDYFTRKGLGASIGRQPQRMRRLVEAIKG 117

Query: 140 VLPNKFSISVKIRL-LNDIKKTVILCQQLEKCG--VTFLTSMEEHCTKSSGPVDINGLKE 196
            + N   ++ KIRL  ND  +  +   Q    G              +     D + +  
Sbjct: 118 SVTN-IPVTAKIRLGWNDDDRNYLQQAQAAVDGGAAALFVHGRTRNARYRFAADWDAIAR 176

Query: 197 VREALSVPMVANG 209
           +  A+ VP++ NG
Sbjct: 177 IVAAVPVPVIGNG 189


>UniRef50_UPI0000DAE45A Cluster: hypothetical protein
           Rgryl_01000346; n=1; Rickettsiella grylli|Rep:
           hypothetical protein Rgryl_01000346 - Rickettsiella
           grylli
          Length = 330

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 5/135 (3%)

Query: 25  APMVRYSKVHFRTLVRNF--NADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           APM+ ++  H+    R     A L +T M  A +  + S AR         +  +  Q  
Sbjct: 15  APMLGWTTRHYHYFFRLICKKAQL-YTEMFTAQAILK-SPARERLLTVDANEKALAIQLG 72

Query: 83  ANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141
                D   A+K+V  Y    ++LN GCP +     G+G  LL +P  + D +  ++ V+
Sbjct: 73  GGIASDLSKAAKIVESYGYSEINLNVGCPSEKVQSGGFGVVLLKEPNRVADAIAAMKAVV 132

Query: 142 PNKFSISVKIRLLND 156
               ++  +I + ND
Sbjct: 133 RLPVTVKTRIGVDND 147


>UniRef50_Q2RZL4 Cluster: NifR3 family enzyme; n=1; Salinibacter
           ruber DSM 13855|Rep: NifR3 family enzyme - Salinibacter
           ruber (strain DSM 13855)
          Length = 443

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 43/190 (22%), Positives = 78/190 (41%), Gaps = 6/190 (3%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           APM   S   FR L + + AD+ +T  + +    +  +    +      + P+  Q    
Sbjct: 80  APMEDVSDPPFRILCKRYGADMMYTEFVSSAGLLREQEHEHQKLEIFDEERPIGIQVWGG 139

Query: 85  NRDDFVDASKLVYPY-VDGVDLNCGCP-QKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
             D+  +A+ +V     D +D+N GCP +K   KDG G  +L   + + +I   +     
Sbjct: 140 GIDEVRNATPMVDAAGPDVIDINFGCPVRKIVQKDG-GAGVLRNLDKMRNITAAVMEEAT 198

Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVRE-- 199
              ++  ++   +D    V + + LE  GV  LT        K  G      L+ ++E  
Sbjct: 199 RPVTVKTRLGWDDDSIHIVDVARMLEDMGVAALTVHARTREQKYKGDARWEWLRTIKEEG 258

Query: 200 ALSVPMVANG 209
              +P + NG
Sbjct: 259 TRDMPFIGNG 268


>UniRef50_Q7UBC5 Cluster: tRNA-dihydrouridine synthase A; n=231;
           Bacteria|Rep: tRNA-dihydrouridine synthase A - Shigella
           flexneri
          Length = 330

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 45/215 (20%), Positives = 94/215 (43%), Gaps = 22/215 (10%)

Query: 25  APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           APM+ ++  H R  +R  + + L +T M+   +       + +    +  + PV  Q   
Sbjct: 16  APMLDWTDRHCRYFLRLLSRNTLLYTEMVTTGAIIHG---KGDYLAYSEEEHPVALQLGG 72

Query: 84  NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
           ++       +KL      D ++LN GCP        +G  L+   +++ D VK +R+V+ 
Sbjct: 73  SDPAALAQCAKLAEARGYDEINLNVGCPSDRVQNGMFGACLMGNAQLVADCVKAMRDVV- 131

Query: 143 NKFSISVKIRL-LNDIKKTVILCQQLE------KCGV-------TFLTSMEEHCTKSSGP 188
               ++VK R+ ++D      LC  +       +C +        +L+ +     +   P
Sbjct: 132 -SIPVTVKTRIGIDDQDSYEFLCDFINTVSGKGECEMFIIHARKAWLSGLSPKENREIPP 190

Query: 189 VDINGLKEV-REALSVPMVANGGVKHLNDATTYMK 222
           +D   + ++ R+   + M  NGG+K L +A  +++
Sbjct: 191 LDYPRVYQLKRDFPHLTMSINGGIKSLEEAKAHLQ 225


>UniRef50_Q2NEG1 Cluster: PyrD; n=1; Methanosphaera stadtmanae DSM
           3091|Rep: PyrD - Methanosphaera stadtmanae (strain DSM
           3091)
          Length = 306

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 6/101 (5%)

Query: 76  PVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVK 135
           PVIA    ++ + F D +     YVD  +LN  CP     K G+G ++   PE+ +DIV 
Sbjct: 94  PVIASIYGDSEEVFSDVANQTKDYVDAFELNVSCPH---AKCGFGSNIGENPELTHDIVS 150

Query: 136 GLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176
            +++   N   + + ++L  ++     + +  E  G   LT
Sbjct: 151 SVKD---NIKDVPIIVKLTPNVTDITEIAKAAEDAGADALT 188


>UniRef50_Q2IG49 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=2; Anaeromyxobacter|Rep: Dihydrouridine
           synthase TIM-barrel protein nifR3 - Anaeromyxobacter
           dehalogenans (strain 2CP-C)
          Length = 352

 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 38/195 (19%), Positives = 75/195 (38%), Gaps = 2/195 (1%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           AP+   S   FR + R   A   +T M+ A      +   ++       + P   Q  A+
Sbjct: 15  APLAGVSDRPFRAICRRMGASFAYTEMVSAHGLMHGALQTSSYLDREPDEDPFAVQIFAS 74

Query: 85  NRDDFVDASKLVYPYVDG-VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143
             D     + +      G +D+N  CP K     G G ++   P  + + V+ +R  +P 
Sbjct: 75  EPDVLARGAVVAVQAGAGMIDVNMACPVKKVCGSGAGAAMGRDPRKVEEAVRAIRAAVPV 134

Query: 144 KFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREALS 202
             ++ ++          V + +  E  G   +           SG      ++ V++A++
Sbjct: 135 PVTVKIRAGWDEGEVNCVDVARAAEAGGAAAVALHGRTRSQLYSGKARWELVRAVKQAVA 194

Query: 203 VPMVANGGVKHLNDA 217
           +P++ +G V    DA
Sbjct: 195 IPVLGSGDVWTAGDA 209


>UniRef50_Q4Q231 Cluster: Dihydrouridine synthase domain
           protein-like protein; n=3; Leishmania|Rep:
           Dihydrouridine synthase domain protein-like protein -
           Leishmania major
          Length = 455

 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 15/51 (29%), Positives = 35/51 (68%)

Query: 100 VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVK 150
           +DG+D+N GCP+K+++ +G+G +L+ +PE+   IV+ +   + +  ++  +
Sbjct: 144 IDGIDINMGCPKKFSVHNGFGAALMKRPEVGGAIVRAVHGAVNSDSNVEAR 194


>UniRef50_A1AT39 Cluster: Dihydrouridine synthase, DuS; n=7;
           Desulfuromonadales|Rep: Dihydrouridine synthase, DuS -
           Pelobacter propionicus (strain DSM 2379)
          Length = 342

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 44/194 (22%), Positives = 78/194 (40%), Gaps = 7/194 (3%)

Query: 25  APMVRYSKVHFRTLVRNF-NADLCFTPMILADSFCQNSKARANEFMTTTT---DFPVIAQ 80
           APM   +    R+L  ++   D+ FT  +  +      +  A +     +   D P++ Q
Sbjct: 39  APMQGVTNSALRSLFIDWVRPDVVFTEFMRVNPAAAQRRLSAADLAEAGSAGDDVPLVVQ 98

Query: 81  FAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139
              + R+  V  S+         ++LN GCP         G  +L  P+ +  I+  LR 
Sbjct: 99  LIGHGREALVSGSQAAQDAGAAHINLNMGCPYGRMTSGQTGGGMLRSPQELSSIIPALRK 158

Query: 140 VLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVR 198
            +   FSI ++    N  ++   L    E  GV FL         K +G  D     E  
Sbjct: 159 TIRGTFSIKLRSGYDNP-RQIFDLLPLFEASGVDFLVLHPRTVLQKYAGFADHGITAEAV 217

Query: 199 EALSVPMVANGGVK 212
           +  ++P++ANG ++
Sbjct: 218 QRSTLPIIANGDIR 231


>UniRef50_Q06053 Cluster: tRNA-dihydrouridine synthase 3; n=6;
           Saccharomycetales|Rep: tRNA-dihydrouridine synthase 3 -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 609

 Score = 46.0 bits (104), Expect = 7e-04
 Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 5/135 (3%)

Query: 22  KVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVI-AQ 80
           K+ +P+     + +R L+R   AD+ ++ M LA    Q + +        T++FP    Q
Sbjct: 295 KIVSPLTTVGNLPYRRLMRKLGADVTYSEMALAVPLIQGTNSEWALPKAHTSEFPGFGVQ 354

Query: 81  FAANNRDDFVDASKLV---YPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGL 137
            A +       A++ +      +  ++LN GCP     + G G +LL  P  +   +  +
Sbjct: 355 VACSKAWQAAKAAEALANSVSEISEINLNSGCPIDLLYRQGSGSALLDNPARMIRCLNAM 414

Query: 138 RNVLPNKFSISVKIR 152
            N +     I+VKIR
Sbjct: 415 -NYVSKDIPITVKIR 428


>UniRef50_Q5ZVH8 Cluster: Zinc binding TIM barrel protein, YjbN
           family; n=4; Legionella pneumophila|Rep: Zinc binding
           TIM barrel protein, YjbN family - Legionella pneumophila
           subsp. pneumophila (strain Philadelphia 1 /ATCC 33152 /
           DSM 7513)
          Length = 334

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 31/142 (21%), Positives = 63/142 (44%), Gaps = 4/142 (2%)

Query: 16  INKTYLKVC-APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTD 74
           +N  + K+  APM+ ++   FRTL+R    +      +      QN+  RA  F   + +
Sbjct: 6   VNSIFSKLSIAPMIDWTNSPFRTLMRLLAPNALLYTEMQTTGAVQNNPDRALYF--NSVE 63

Query: 75  FPVIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDI 133
            P+  Q    ++   V  + +      + ++LN GCP        +G  L+ +PE + D 
Sbjct: 64  HPLAIQLGGADKSALVKCAIIAEQKGFNEINLNLGCPSDKVQAGRFGACLMKEPEHVADC 123

Query: 134 VKGLRNVLPNKFSISVKIRLLN 155
           ++ ++ V+    +   +I + N
Sbjct: 124 IRAIKQVVGIPVTAKTRIGIDN 145


>UniRef50_Q8SUY1 Cluster: Putative uncharacterized protein
           ECU07_1170; n=1; Encephalitozoon cuniculi|Rep: Putative
           uncharacterized protein ECU07_1170 - Encephalitozoon
           cuniculi
          Length = 357

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 28/112 (25%), Positives = 54/112 (48%), Gaps = 3/112 (2%)

Query: 25  APMVRYSKVHFRTLVR-NFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           APM+  +  HFR  +R      + FT MI++++     + +  E +    D  V+ Q   
Sbjct: 18  APMMDVTTAHFRRFIRLTSEKTVLFTEMIVSNTVIHVPRDKLRERLGEYDDRTVV-QIGG 76

Query: 84  NNRDDFVDASKLVYPYVDGV-DLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134
           ++    V+A +++      + +LNCGCP     K  +G  L+   E++ +I+
Sbjct: 77  SDATSMVEAVRILQGLGYRMFNLNCGCPSSRVKKGSFGAVLMLNRELVAEII 128


>UniRef50_Q6AJ40 Cluster: Putative uncharacterized protein; n=1;
           Desulfotalea psychrophila|Rep: Putative uncharacterized
           protein - Desulfotalea psychrophila
          Length = 318

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 25/89 (28%), Positives = 43/89 (48%), Gaps = 1/89 (1%)

Query: 76  PVIAQFAANNRDDFVD-ASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134
           PVI Q   NN +DF+  A +L       ++ N GCP     K   G  +L+ P++I + +
Sbjct: 64  PVIPQLLHNNAEDFIALAGRLAELGYKEINWNLGCPAPMVAKKKRGSGMLAHPDLIVEFL 123

Query: 135 KGLRNVLPNKFSISVKIRLLNDIKKTVIL 163
           + +   +P K SI  ++   N  +   +L
Sbjct: 124 EEVLPQIPVKLSIKTRLGYSNTAQTKELL 152


>UniRef50_A5GPV9 Cluster: TRNA-dihydrouridine synthase A; n=21;
           Cyanobacteria|Rep: TRNA-dihydrouridine synthase A -
           Synechococcus sp. (strain RCC307)
          Length = 335

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 28/115 (24%), Positives = 56/115 (48%), Gaps = 4/115 (3%)

Query: 25  APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           APM+ Y+  HFR ++R  +   L +T M++A +     +     F     + P+  Q   
Sbjct: 19  APMMDYTDRHFRVVMRQVSRHALLYTEMVVAQALHHGRQDTLLGF--DPLEKPIALQLGG 76

Query: 84  NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGL 137
           ++     +A++L   +  D ++LN GCP     K  +G  L+++P+ +   V+ +
Sbjct: 77  DDPALLAEAAELAERWGYDEINLNVGCPSPKVKKGRFGACLMAEPQQVARCVEAM 131


>UniRef50_A0EAZ6 Cluster: Chromosome undetermined scaffold_87, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_87,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 346

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 6/133 (4%)

Query: 25  APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMT--TTTDFPVIAQF 81
           APM+  +  HFR   R    + + +T MI  ++   +   +    +   +  + PV+ Q 
Sbjct: 12  APMIDITYEHFRVFFRLLTKNCVLYTEMIHENAINLSRVLKPFPLVLDYSQVEHPVVCQL 71

Query: 82  AANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140
             N+ +    A+++      D ++LN GCP +      +G  L+ +P ++   +K ++  
Sbjct: 72  GGNDPEKLAKAAQIAEQAGFDEINLNVGCPSERVQDGAFGACLMKEPHLVAQCMKKMKEA 131

Query: 141 LPNKFSISVKIRL 153
           +  K   ++K RL
Sbjct: 132 V--KIPCTLKCRL 142


>UniRef50_O31546 Cluster: Probable tRNA-dihydrouridine synthase 2;
           n=10; Bacilli|Rep: Probable tRNA-dihydrouridine synthase
           2 - Bacillus subtilis
          Length = 325

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 36/135 (26%), Positives = 62/135 (45%), Gaps = 7/135 (5%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNA-DLCFTPMILADSFCQ-NSKARANEFMTTTTDF-PVIA 79
           V APM   + V FR +V      D+ FT    ++S+C  + K      +T T D  P++A
Sbjct: 15  VLAPMEDVTDVVFRHVVSEAGRPDVFFTEFTNSESYCHPDGKDSVRGRLTFTEDEQPIVA 74

Query: 80  QFAANNRDDFVDAS-KLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLR 138
               +  ++F   S  +      G+D+N GCP      +G G  L+ +P +  ++++  +
Sbjct: 75  HIWGDKPENFRKMSIGMAELGFKGLDINMGCPVPNVAGNGKGSGLICRPAVAAELIQAAK 134

Query: 139 NVLPNKFSISVKIRL 153
                   +SVK RL
Sbjct: 135 ---AGGLPVSVKTRL 146


>UniRef50_UPI000058804E Cluster: PREDICTED: similar to MGC53781
           protein; n=3; Deuterostomia|Rep: PREDICTED: similar to
           MGC53781 protein - Strongylocentrotus purpuratus
          Length = 655

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 39/200 (19%), Positives = 81/200 (40%), Gaps = 4/200 (2%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           AP+     + FR + +   AD+    M +  +  Q   +         ++     Q    
Sbjct: 287 APLTTVGNLPFRAVCKKLGADITCGEMAMCTNLLQGQSSEWALLRRHPSEDIFGVQLCGG 346

Query: 85  NRDDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
             D     ++L+     +D +D+N GCP       G G  L+++     +IV+G+ +VL 
Sbjct: 347 FPDTMTRCAELLNDRLDIDFIDINVGCPIDLVYHKGAGSGLMNRMGKFQEIVRGMSSVLD 406

Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKE-VREA 200
              ++ ++  + ND      + +++   G + +T        + S   D + LK+ V+ A
Sbjct: 407 IPLTVKMRTGVHNDNPVAHKIVRRIYDWGASVVTVHGRTREQRYSKLADWDYLKDCVQAA 466

Query: 201 LSVPMVANGGVKHLNDATTY 220
              P + NG +    D+  +
Sbjct: 467 DPHPFIGNGDILSYEDSNFF 486


>UniRef50_Q2RTR9 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=1; Rhodospirillum rubrum ATCC 11170|Rep:
           Dihydrouridine synthase TIM-barrel protein nifR3 -
           Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)
          Length = 362

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 42/203 (20%), Positives = 87/203 (42%), Gaps = 6/203 (2%)

Query: 21  LKVCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDF----P 76
           L + APM   +   FR L  ++   L +T M+ +    +      +  +    +     P
Sbjct: 13  LIMLAPMAGVTDSPFRRLAHDYGCPLSWTEMVASRELLRERARGVDPRLGGGAEAGRAGP 72

Query: 77  VIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVK 135
              Q A  +     +A++ V     + +D+N GCP +  +    G +L+    +   I++
Sbjct: 73  FAVQLAGCDPLIMAEAARRVEGAGAELIDINMGCPVRKVVGGLGGSALMRDLPLAARILE 132

Query: 136 GLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM-EEHCTKSSGPVDINGL 194
            +   +    S+ +++   +  +  V L +  E  G++ LT           G  D   +
Sbjct: 133 AVVGAVTLPVSLKMRLGWDDASRNAVELARLAESAGISRLTVHGRTRAQMYDGRADWPAI 192

Query: 195 KEVREALSVPMVANGGVKHLNDA 217
             V+ A+S+P++ANG V +L++A
Sbjct: 193 GLVKRAVSLPVIANGDVTNLSEA 215


>UniRef50_A4RVX6 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 371

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 5/113 (4%)

Query: 103 VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLNDIKKTVI 162
           +DLNCGCP       G G SLL  PE +Y  VK + +         V ++L +    + +
Sbjct: 95  IDLNCGCPANVVTGKGAGSSLLRDPEYVYACVKAVADGARGS-GAHVTMKLRSGYDDSSL 153

Query: 163 LCQQL---EKCGVTFLT-SMEEHCTKSSGPVDINGLKEVREALSVPMVANGGV 211
           L + L    + G  F++          SG  +   +   ++ L +P++ NG V
Sbjct: 154 LRENLLAAREAGARFVSLHARTRAQGYSGRANWEEIAFAKDVLDIPVLGNGDV 206


>UniRef50_Q9VIS4 Cluster: CG10463-PA; n=3; Sophophora|Rep:
           CG10463-PA - Drosophila melanogaster (Fruit fly)
          Length = 604

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 46/202 (22%), Positives = 85/202 (42%), Gaps = 11/202 (5%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           V +P+     + FR + + F AD+    M  A    +             ++     Q  
Sbjct: 260 VLSPLTTLGNLPFRRICKEFGADITCGEMACAQPLLKGMGQEWALTKRHQSEDVFGVQLC 319

Query: 83  ANNRDDFVDASKLVYP--YVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140
            NN +    A+++++    VD +DLN GCP     + G G +L+ +  I+   V+     
Sbjct: 320 GNNPNMLNQAAQVIHETAQVDFIDLNIGCPIDLIYQQGGGSALMRRTNILELTVRSCA-A 378

Query: 141 LPNKFSISVKIRLLNDIKKTVI--LCQQLEKCGVTFLT----SMEEHCTKSSGPVDINGL 194
           L ++   +VK+R      K+V   L   +E+ G + +T    S E+  TK +    I   
Sbjct: 379 LSDRLPFTVKMRTGIYADKSVAHELLPLVEEWGASAVTLHGRSREQRYTKHANWAYIE-- 436

Query: 195 KEVREALSVPMVANGGVKHLND 216
           +   +A  +P++ NG +    D
Sbjct: 437 ECAAKAKCMPVIGNGDILSYED 458


>UniRef50_Q7UKE8 Cluster: Putative uncharacterized protein; n=2;
           Planctomycetaceae|Rep: Putative uncharacterized protein
           - Rhodopirellula baltica
          Length = 364

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 47/196 (23%), Positives = 83/196 (42%), Gaps = 11/196 (5%)

Query: 25  APMVRYSKVHFRTLVRNF-NADLCFTPMILADSF--CQNSKARANEFMTTTTD--FPVIA 79
           APM  ++   FR +VR F  A L  T M+ A  F     ++A   + +    D   P+  
Sbjct: 33  APMAGFTNAAFRHIVRQFGGAGLLATEMVNARGFVWLDENEAEHPDRLWGVADEPRPLAV 92

Query: 80  QFAANNRDDFVDAS-KLVYPY-VDGVDLNCGCPQKWAMKDGY-GCSLLSKPEIIYDIVKG 136
           Q   N+ +       +L   Y V  VD+N GCP +   +  + G  LL +P  ++ I+  
Sbjct: 93  QIWDNDPETMAKVGRRLAEEYRVSVVDINFGCPVRQVTEKAHSGSYLLREPNRMHAIISR 152

Query: 137 LRNV-LPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSMEEHCTKS-SGPVDINGL 194
           L  V  P   +  +++    +      + + +E+ G   LT           G  D   +
Sbjct: 153 LVQVCAPTPVTAKIRLGCSRENINCNEIARVVEEAGAAALTVHGRTAADMFRGNADWERI 212

Query: 195 KEVREAL-SVPMVANG 209
            E++  L ++P++ NG
Sbjct: 213 SEIKSHLRNIPLIGNG 228


>UniRef50_A1IED4 Cluster: Putative uncharacterized protein; n=1;
           Candidatus Desulfococcus oleovorans Hxd3|Rep: Putative
           uncharacterized protein - Candidatus Desulfococcus
           oleovorans Hxd3
          Length = 324

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 48/203 (23%), Positives = 85/203 (41%), Gaps = 9/203 (4%)

Query: 21  LKVCAPMVRYSKVH-FRT-LVRNFNA-DLCFTPMILADSFCQNSKARANEFMTT-TTDFP 76
           + +C   +R    H FRT    +F   D    P + +    +   A   + +    T  P
Sbjct: 3   MTLCMAPIRGITDHIFRTAFAEHFGGFDTAVAPFVSSRKDRKIKSAHLKDLLPEYNTALP 62

Query: 77  VIAQFAANNRDDFVDASKLVYPYVDGV-DLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVK 135
           V+ Q  +N+ +DFV  +  +Y     V + N GCP     K   G  LL   + I + + 
Sbjct: 63  VVPQILSNSGEDFVYLADHLYDLGYSVTNWNLGCPYPMVAKKYRGAGLLPHTDRIAEFLD 122

Query: 136 GLRNVLPNKFSISVKIRL-LNDIKKTVILCQQLEKCGVT-FLTSMEEHCTKSSGPVDING 193
            + + +  K  +SVKIRL   D  + + L   L +  +   +        +  G VD+  
Sbjct: 123 TVMSRM--KGGLSVKIRLGWADTTELMGLLPVLHRYPLAELIVHPRTGIQRYEGTVDLAA 180

Query: 194 LKEVREALSVPMVANGGVKHLND 216
            + V E   +P++ NG ++ + D
Sbjct: 181 FERVLENTGLPVMYNGDIQTVAD 203


>UniRef50_Q01ML2 Cluster: H0613H07.1 protein; n=10; Eukaryota|Rep:
           H0613H07.1 protein - Oryza sativa (Rice)
          Length = 685

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 34/154 (22%), Positives = 58/154 (37%), Gaps = 2/154 (1%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           AP+     + FR L +   AD+    M +  +  Q   +        +++     Q    
Sbjct: 337 APLTTVGNLPFRRLCKTLGADITCGEMAMCTNLLQGQASEWALLRRHSSEDLFGVQICGA 396

Query: 85  NRDDFVDASKLVYPY--VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
             D      +LV     VD +D+N GCP    +  G G SLL+KP  I  IV+    V  
Sbjct: 397 YPDTVARTVELVDNECSVDFIDINMGCPIDIVVNKGAGSSLLTKPMRIKSIVQAASTVTE 456

Query: 143 NKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT 176
              ++ V+        +   +   +   G + +T
Sbjct: 457 KPLTVKVRTAFFEGRNRADSIVSDIYDWGASAIT 490


>UniRef50_Q5FTP7 Cluster: Nitrogen assimilation regulatory protein
           NifR3; n=3; Acetobacteraceae|Rep: Nitrogen assimilation
           regulatory protein NifR3 - Gluconobacter oxydans
           (Gluconobacter suboxydans)
          Length = 371

 Score = 43.2 bits (97), Expect = 0.005
 Identities = 42/201 (20%), Positives = 88/201 (43%), Gaps = 10/201 (4%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           + AP+   + + FR L R+  A L  + MI + +  + ++             P   Q A
Sbjct: 38  ILAPLSGVTDLPFRQLARDLGAGLVVSEMIASWAMIRENE-NTMRMARMAERGPNAVQLA 96

Query: 83  ANNRDDFVDASKLVYPYVDG----VDLNCGCP-QKWAMKDGYGCSLLSKPEIIYDIVKGL 137
             +      A+K+    VDG    +D+N GCP +K A+    G +L+    +   +++  
Sbjct: 97  GCDPKAMAQAAKIS---VDGGANLIDINFGCPVKKVAIGQMAGSALMRDEVLAGKLLEAT 153

Query: 138 RNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM-EEHCTKSSGPVDINGLKE 196
              +    ++ +++   ++      L +  E+ G+  +T          +G  D   +K 
Sbjct: 154 ARAVNVPVTLKMRMGWDHNSLNAPRLAKIAEESGIRLVTVHGRTRQMFYNGTADWRFVKT 213

Query: 197 VREALSVPMVANGGVKHLNDA 217
           V++A+S+P++ NG +  + DA
Sbjct: 214 VKDAVSLPVIVNGDINTIRDA 234


>UniRef50_A6PPM6 Cluster: Dihydrouridine synthase, DuS; n=1;
           Victivallis vadensis ATCC BAA-548|Rep: Dihydrouridine
           synthase, DuS - Victivallis vadensis ATCC BAA-548
          Length = 343

 Score = 43.2 bits (97), Expect = 0.005
 Identities = 47/193 (24%), Positives = 81/193 (41%), Gaps = 9/193 (4%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAAN 84
           AP+  ++ + +R   R       FT M+   S     +  A        +  +  Q    
Sbjct: 21  APLSGFTDLPYRRAARAGGCRFAFTEMVDVASLTYARERSAGMLRRGPEEEFLGVQLVGA 80

Query: 85  NRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN 143
           + +    A+ +V  Y    VD N GCP     K G G  L    +        +     +
Sbjct: 81  DHEFIRRAADVVNEYEFSVVDFNLGCPVPKVAKKGAGAELGRHLDAALACFAIIAE--RS 138

Query: 144 KFSISVKIRLLN--DIKKTVILCQQLEKCGVTFLTSMEEHCTKS--SGPVDINGLKEVRE 199
           +  ++ KIR+++  D   T+ L + L + G   +T +     ++  SGPV+   ++ VRE
Sbjct: 139 RHPVTAKIRIVDAEDPAPTLALAKGLAELGAQAIT-VHGRIKEAFYSGPVNFGMIRAVRE 197

Query: 200 AL-SVPMVANGGV 211
           AL  V ++ANGGV
Sbjct: 198 ALPGVQVIANGGV 210


>UniRef50_A5N517 Cluster: Predicted NADH oxidase; n=1; Clostridium
           kluyveri DSM 555|Rep: Predicted NADH oxidase -
           Clostridium kluyveri DSM 555
          Length = 328

 Score = 43.2 bits (97), Expect = 0.005
 Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 11/113 (9%)

Query: 116 KDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLN------DIKKTVILCQQLEK 169
           +D YG  +  + +I  DIVK +R  +   F I +++   +       I+ + +  QQLEK
Sbjct: 186 QDEYGGDITGRIKIHRDIVKNVREAVGESFPIFMRLGASDYMDGGLTIEDSKLAAQQLEK 245

Query: 170 CGVTFLTSMEEHCTKSSGPVDINGL-----KEVREALSVPMVANGGVKHLNDA 217
            GV  L      C  +   V+  G      K ++E +S+P++  GG+ H   A
Sbjct: 246 TGVDVLDISGGLCRYTIPGVNEEGYFTPLSKAIKEVVSIPVIVTGGIIHAKTA 298


>UniRef50_Q2HDP2 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 641

 Score = 43.2 bits (97), Expect = 0.005
 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 4/78 (5%)

Query: 79  AQFAANNRDDFVDASKLV---YPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVK 135
           AQ AAN     V A++ +    P++  VDLNCGCP     K G G +LL     +  +++
Sbjct: 311 AQIAANAPWVAVKATEALSQLLPHLRLVDLNCGCPVDAVFKSGSGSALLDSHSKLERMIR 370

Query: 136 GLRNVLPNKFSISVKIRL 153
           G+ N +  +  I+ KIR+
Sbjct: 371 GM-NAVSGEVPITAKIRM 387


>UniRef50_A0Z3E6 Cluster: Dihydroorotate
           dehydrogenase/oxidoreductase, FAD-binding protein; n=5;
           Bacteria|Rep: Dihydroorotate
           dehydrogenase/oxidoreductase, FAD-binding protein -
           marine gamma proteobacterium HTCC2080
          Length = 551

 Score = 42.7 bits (96), Expect = 0.007
 Identities = 27/111 (24%), Positives = 54/111 (48%), Gaps = 6/111 (5%)

Query: 32  KVHFRTLVRNFNADLCFTPMI-LADSFCQNSKARANEFMTTTTDFPVIAQFAANNRDDFV 90
           ++ +R  V +  A  CF   + L +     S A   +       F +++ F  +  ++FV
Sbjct: 51  RLGYREPVYSQFAPGCFVNAVGLTNPGAHASLASLGQLRVPEDRFLLVSIFGGSV-EEFV 109

Query: 91  DASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141
             +K++ P  DG +LN  CP       GYG ++   P+I+++I+  ++ V+
Sbjct: 110 AVAKILEPVADGFELNLSCPH----ASGYGMAMGQDPKIVHEIIAAVKQVV 156


>UniRef50_Q582L4 Cluster: TRNA-dihydrouridine synthase 3, putative;
           n=3; Trypanosoma|Rep: TRNA-dihydrouridine synthase 3,
           putative - Trypanosoma brucei
          Length = 528

 Score = 42.7 bits (96), Expect = 0.007
 Identities = 33/136 (24%), Positives = 61/136 (44%), Gaps = 8/136 (5%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFA 82
           V AP+     + FR + + + AD+    M +  +  +  K+  +     +++     Q A
Sbjct: 169 VLAPLTTVGNLPFRRVCKEYGADITVGEMAIVHNLNRLQKSEWSLLRRHSSEDIFGLQIA 228

Query: 83  ANNRDDFVDASKLV----YPYVDGVDLNCGCPQKWAMKDGYGCSLLS-KPEIIYDIVKGL 137
            +   D +  ++ V    + Y D VD+NCGCP    +  G GC L   K   + D+V+ L
Sbjct: 229 VSRPHDAITWAQAVEESGFSY-DFVDINCGCPVDKVVLSGCGCGLWERKGNRLRDVVQSL 287

Query: 138 RNVLPNKFSISVKIRL 153
             V      +++K R+
Sbjct: 288 --VAHQSKPVTIKCRM 301


>UniRef50_Q8A2H9 Cluster: Putative nifR3 family TIM-barrel enzyme
           with dihydrouridine synthase domain; n=6;
           Bacteroidales|Rep: Putative nifR3 family TIM-barrel
           enzyme with dihydrouridine synthase domain - Bacteroides
           thetaiotaomicron
          Length = 314

 Score = 42.3 bits (95), Expect = 0.009
 Identities = 37/119 (31%), Positives = 53/119 (44%), Gaps = 10/119 (8%)

Query: 103 VDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN--KFSISVKIRL-LNDIKK 159
           VD+N GCP     K   G  +L  PE     VK L +++    + S SVK+RL      +
Sbjct: 91  VDINLGCPFPLLAKRHNGSGILPYPEE----VKALLSIVTRYPQISFSVKMRLGWEQPDE 146

Query: 160 TVILCQQLEKCGVTFLTSMEEHCTKSS--GPVDINGLKEVREALSVPMVANGGVKHLND 216
            + L   L    +  +T M     K    G VD+ G    RE   +P+V NG + +L D
Sbjct: 147 CLALAPILNDLPLRQIT-MHPRLGKQGYKGEVDLQGFSAFREVCQLPLVYNGDIHNLED 204


>UniRef50_Q83D40 Cluster: TIM-barrel protein, yjbN family; n=7;
           Bacteria|Rep: TIM-barrel protein, yjbN family - Coxiella
           burnetii
          Length = 353

 Score = 41.9 bits (94), Expect = 0.012
 Identities = 30/130 (23%), Positives = 58/130 (44%), Gaps = 6/130 (4%)

Query: 25  APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           APM+  +  HFR  +R  +   L +T M+   +  +  + R  ++  +  + P+  Q   
Sbjct: 34  APMMGCTDRHFRMFMRQISRHVLLYTEMVTTGALLKGKQWRCLDY--SPEEHPLALQVGG 91

Query: 84  NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
           ++       ++L      D ++LN GCP    +   +G  LL + E++ D V  +   + 
Sbjct: 92  SDPQSLALCARLAEEKGFDEINLNVGCPSGRVIAGRFGACLLKEAELVADCVAAMSAEV- 150

Query: 143 NKFSISVKIR 152
               +SVK R
Sbjct: 151 -NIPVSVKTR 159


>UniRef50_A5FPW7 Cluster: Dihydroorotate dehydrogenase family
           protein; n=21; Bacteria|Rep: Dihydroorotate
           dehydrogenase family protein - Dehalococcoides sp. BAV1
          Length = 324

 Score = 41.9 bits (94), Expect = 0.012
 Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 17/166 (10%)

Query: 72  TTDFPVIAQFAANNRDDFVDASKLV--YPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEI 129
           T D PVI   AA + +D+ + ++ +   P V G+++N  CP        +G S  S  ++
Sbjct: 112 TWDVPVIVNIAAESIEDYAELARRLDKVPGVSGIEVNISCPNVKCGCIEFGSSPESAAKV 171

Query: 130 IYDIVKG------LRNVLPNKFSISVKIRLLNDIKKTVI-LCQQLEKCGVTFLTS---ME 179
             D+V+       +  + PN  SI+   + + D     I L   L    +        + 
Sbjct: 172 T-DVVRNATTLPLIVKLTPNTSSITELAKAVADAGADAISLINTLRGMRIDIKKRRPVLG 230

Query: 180 EHCTKSSGP----VDINGLKEVREALSVPMVANGGVKHLNDATTYM 221
            H    SGP    V I+ + +V  A++VP++  GG+ +  DA  ++
Sbjct: 231 NHTGGLSGPAIKPVAISMVYQVAGAVNVPVIGGGGIMNAEDALEFL 276


>UniRef50_Q9UTH9 Cluster: tRNA dihydrouridine synthase Dus3; n=1;
           Schizosaccharomyces pombe|Rep: tRNA dihydrouridine
           synthase Dus3 - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 617

 Score = 41.9 bits (94), Expect = 0.012
 Identities = 20/56 (35%), Positives = 33/56 (58%), Gaps = 1/56 (1%)

Query: 100 VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLN 155
           VD +DLNCGCP     + G G SLL  P  +   ++G+ + +  +  ++VK+R+ N
Sbjct: 331 VDFLDLNCGCPIDLVFRQGAGSSLLENPGRLLRNLQGM-DAVSGQIPVTVKLRMGN 385


>UniRef50_A7DKP5 Cluster: Dihydrouridine synthase, DuS; n=2;
           Methylobacterium extorquens PA1|Rep: Dihydrouridine
           synthase, DuS - Methylobacterium extorquens PA1
          Length = 354

 Score = 41.5 bits (93), Expect = 0.016
 Identities = 31/132 (23%), Positives = 58/132 (43%), Gaps = 8/132 (6%)

Query: 25  APMVRYSKVHFRTLVRNFNADL-CFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           APM+ ++    R   R  +     +T M+   +     + R   F     + P+  Q   
Sbjct: 33  APMMDWTDRQCRAFHRTLSRRARLYTEMVTTGAVLHGDRERLLGF--DAYEQPLAVQLGG 90

Query: 84  NNRDDFVDASKLV--YPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVL 141
           +N DD   A+++   + Y + ++LN GCP        +G  L+ +P ++   V  L+  +
Sbjct: 91  SNPDDLAAAARIAADFGYAE-INLNVGCPSDRVQDGRFGACLMREPGLVGACVAALKAAV 149

Query: 142 PNKFSISVKIRL 153
           P    ++VK RL
Sbjct: 150 P--VPVTVKCRL 159


>UniRef50_A4BWB1 Cluster: Putative uncharacterized protein; n=5;
           Bacteroidetes|Rep: Putative uncharacterized protein -
           Polaribacter irgensii 23-P
          Length = 317

 Score = 41.1 bits (92), Expect = 0.021
 Identities = 32/133 (24%), Positives = 59/133 (44%), Gaps = 6/133 (4%)

Query: 25  APMVRYSKVHFRTLVRNF--NADLCFTPMI-LADSFCQNSKARANEFMTTTTDFPVIAQF 81
           +P+  ++   FR    +F    D  ++P I L       +  + +  +   ++  VI Q 
Sbjct: 8   SPLQGFTDYKFRNAFNHFFGGIDTFYSPYIRLNGKMVIKNSYQKDLLLENNSELEVIPQI 67

Query: 82  AANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNV 140
             N+ ++F+  SK V       ++ N GCP     K G G  L+S  E I  I+  + N 
Sbjct: 68  ITNDAEEFLFVSKYVRALGYKELNWNLGCPYPMVTKRGMGSGLISDAEKINSILHKVHN- 126

Query: 141 LPNKFSISVKIRL 153
             +   +S+K+R+
Sbjct: 127 -ESDILVSMKMRM 138


>UniRef50_A7AWB5 Cluster: Dihydrouridine synthase (Dus) domain
           containing protein; n=1; Babesia bovis|Rep:
           Dihydrouridine synthase (Dus) domain containing protein
           - Babesia bovis
          Length = 362

 Score = 41.1 bits (92), Expect = 0.021
 Identities = 35/134 (26%), Positives = 59/134 (44%), Gaps = 8/134 (5%)

Query: 25  APMVRYSKVHFRTLVRNFNADL-CFTPMILADSFCQNSKARANEFM-TTTTDFPVIAQFA 82
           APM+  +   FR  +R        +T M+   S       +    +     + P++ Q  
Sbjct: 21  APMLDITYYEFRQFMRLITKRAQLWTEMMADGSLIYGDSDKVGSMLHCDANEHPIVLQLG 80

Query: 83  ANNRDDFVDASKLV--YPYVDGVDLNCGCPQ-KWAMKDGYGCSLLSKPEIIYDIVKGLRN 139
            NN D    A  +   Y Y +  +LN GCP  + + K  +G +L++   ++  IVK LR+
Sbjct: 81  GNNLDSLSKAGNIALGYGYTE-FNLNVGCPSTRVSGKGCFGAALMNDAPLVGRIVKHLRS 139

Query: 140 VLPNKFSISVKIRL 153
            L     ++VK RL
Sbjct: 140 ELGT--PVTVKHRL 151


>UniRef50_Q9PGB5 Cluster: tRNA-dihydrouridine synthase A; n=8;
           Proteobacteria|Rep: tRNA-dihydrouridine synthase A -
           Xylella fastidiosa
          Length = 340

 Score = 41.1 bits (92), Expect = 0.021
 Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 8/126 (6%)

Query: 29  RYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAANNRDD 88
           RY +V  R L  +      +T M+ A +     + R   F   + + PV  Q   +    
Sbjct: 29  RYCRVFHRVLAPSARL---YTEMVHAKAVIYGDRERLLGF--ASVEQPVALQLGGSEPAL 83

Query: 89  FVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSI 147
              A+++   +    ++LNCGCP        +G  L+ +P ++ D V  +  V+     +
Sbjct: 84  LAKAARIAVDWGYSEINLNCGCPSDRVQAGSFGARLMREPALVADCVAAMAAVV--SVPV 141

Query: 148 SVKIRL 153
           +VK RL
Sbjct: 142 TVKCRL 147


>UniRef50_Q979G6 Cluster: Dihydroorotate dehydrogenase; n=4;
           Thermoplasmatales|Rep: Dihydroorotate dehydrogenase -
           Thermoplasma volcanium
          Length = 301

 Score = 40.7 bits (91), Expect = 0.028
 Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 9/95 (9%)

Query: 76  PVIAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV 134
           P+I    A N ++F   S  +  Y VD ++LN  CP       G+G  + S P+++ DIV
Sbjct: 94  PIIGSVFAYNAEEFTKLSVKMEEYGVDAIELNLSCPHV----KGFGLEVGSDPDLVEDIV 149

Query: 135 KGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEK 169
               N + +K  + V  +L  ++   + + +  EK
Sbjct: 150 ----NEIKSKVKVPVFAKLSPNVSNIIEIAKAAEK 180


>UniRef50_Q38BB4 Cluster: TRNA-dihydrouridine synthase 2, putative;
           n=3; Trypanosoma|Rep: TRNA-dihydrouridine synthase 2,
           putative - Trypanosoma brucei
          Length = 435

 Score = 40.3 bits (90), Expect = 0.037
 Identities = 18/52 (34%), Positives = 29/52 (55%)

Query: 76  PVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKP 127
           PV+ Q           A+ L    VDG+D+N GCP+K+++ +G G +L+  P
Sbjct: 95  PVVLQLGVAEPAIGARAALLCVDDVDGIDVNMGCPKKFSVDNGMGAALMRDP 146


>UniRef50_Q8G7W8 Cluster: Possible NifR3-like protein; n=4;
           Bifidobacterium|Rep: Possible NifR3-like protein -
           Bifidobacterium longum
          Length = 414

 Score = 39.9 bits (89), Expect = 0.049
 Identities = 49/203 (24%), Positives = 80/203 (39%), Gaps = 9/203 (4%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQF 81
           V +PM   +   FR +   +  D L    MI A +   ++           ++     Q 
Sbjct: 50  VLSPMAGVTNWPFRVICEEYGPDGLYVAEMITARALVAHNPKALRLCHFAKSEKIRSLQL 109

Query: 82  AANNRDDFVDASKLVYP--YVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRN 139
              N      A+K+V      D VDLN GCP     + G G +L  K +I  ++++ +  
Sbjct: 110 YGVNPSITEQAAKIVVDGNMADHVDLNFGCPVPKVTRRGGGSALPWKTDIFTELLQRVVA 169

Query: 140 VL-PNKFSISVKIRLLNDIKKTVIL----CQQLEKCGVTFLTSMEEHCTKSSGPVDINGL 194
           V  P    ++ KIR+  D      L      Q E C    L +         G  D + +
Sbjct: 170 VCEPAGIPVTAKIRVGIDHNHETFLEAGHIAQEEGCKAVTLHA-RTTAEYYGGHSDWSRI 228

Query: 195 KEVREALSVPMVANGGVKHLNDA 217
            E++E L++P+  NG +    DA
Sbjct: 229 GELKEHLNIPVFGNGDIWGAEDA 251


>UniRef50_Q0C0N1 Cluster: Putative tRNA-dihydrouridine synthase;
           n=1; Hyphomonas neptunium ATCC 15444|Rep: Putative
           tRNA-dihydrouridine synthase - Hyphomonas neptunium
           (strain ATCC 15444)
          Length = 345

 Score = 39.9 bits (89), Expect = 0.049
 Identities = 42/193 (21%), Positives = 79/193 (40%), Gaps = 9/193 (4%)

Query: 25  APMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARANEFMTTTTDFPV---IAQF 81
           APM   +    R    +F A    + M+  +     +KARA+    T         I Q 
Sbjct: 26  APMSGATDAPMRRQAVHFGAPAVVSEMVAGEML---AKARADVVRRTCRHEGAGYWIVQL 82

Query: 82  AANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIV-KGLRN 139
           AA   +D +  + L+    VD +D+N GCP K       G +L+    +  +I+   L+ 
Sbjct: 83  AARRPEDMLAGAVLMAEAGVDVIDINMGCPSKQVTGGQSGSALMRDLPLAGEIIDAALQG 142

Query: 140 VLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLT-SMEEHCTKSSGPVDINGLKEVR 198
                 ++ +++   ++      L    +  GV  LT      C   +G  +   ++   
Sbjct: 143 AAGRPVTLKMRLGWDDENLNAPELAVMAQDRGVQMLTVHGRTRCQFYTGGANWAAVRATV 202

Query: 199 EALSVPMVANGGV 211
           +A+S+P++ NG +
Sbjct: 203 DAVSLPVIVNGDI 215


>UniRef50_Q6C4K3 Cluster: Similar to DEHA0D12364g Debaryomyces
           hansenii; n=1; Yarrowia lipolytica|Rep: Similar to
           DEHA0D12364g Debaryomyces hansenii - Yarrowia lipolytica
           (Candida lipolytica)
          Length = 622

 Score = 39.9 bits (89), Expect = 0.049
 Identities = 34/139 (24%), Positives = 62/139 (44%), Gaps = 12/139 (8%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKAR------ANEFMTTTTDFP 76
           + +P+     + +R L+++  AD+ +  M L     Q  KA        +  +T    F 
Sbjct: 250 IVSPLTTVGNLPYRRLMKDLGADVTYGEMALTLPLIQGHKAEWALTRCHSSEVTEGNHFG 309

Query: 77  VIAQFAANNRDDFVDASKLVYPYVDGV---DLNCGCPQKWAMKDGYGCSLLSKPEIIYDI 133
           V  Q  A      + A++ V     G+   +LNCGCP     + G G +L+ +      I
Sbjct: 310 V--QVTAPKHWQAIKAAQAVSELCTGISEINLNCGCPIDLVYRQGAGSALMDQQGKTARI 367

Query: 134 VKGLRNVLPNKFSISVKIR 152
           V+G+ +++     I+VK+R
Sbjct: 368 VRGM-SMVSGDVPITVKMR 385


>UniRef50_Q7PVV7 Cluster: ENSANGP00000016833; n=2;
           Endopterygota|Rep: ENSANGP00000016833 - Anopheles
           gambiae str. PEST
          Length = 594

 Score = 39.5 bits (88), Expect = 0.065
 Identities = 31/120 (25%), Positives = 58/120 (48%), Gaps = 11/120 (9%)

Query: 100 VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPN---KFSISVKIRLLND 156
           VD +DLN GCP       G G +LL +  ++  +V+    +L +   +F++  +I + N+
Sbjct: 327 VDFIDLNTGCPIDLIFNQGGGSALLRRQNVLKVMVQSCSRLLADYGKEFTVKTRIGIYNN 386

Query: 157 IKKTVILCQQLEKCGVTFLT----SMEEHCTKSSGPVDINGLKE-VREALSVPMVANGGV 211
                 +  + E  G + +T    + E+  TK +   D   L++   +A SVP+  NG +
Sbjct: 387 KLIAHEMVPKFEDWGASLITIHGRTKEQRYTKRA---DWEYLQQCATQAQSVPVFGNGDI 443


>UniRef50_Q9K9W1 Cluster: Dihydroorotate dehydrogenase; n=1;
           Bacillus halodurans|Rep: Dihydroorotate dehydrogenase -
           Bacillus halodurans
          Length = 305

 Score = 39.5 bits (88), Expect = 0.065
 Identities = 37/171 (21%), Positives = 80/171 (46%), Gaps = 31/171 (18%)

Query: 74  DFPVIAQFAANNRDDFVDASKLV--YPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIY 131
           D P++A  A +  +D+V+ ++ +     V  ++LN  CP    +K+G G +  + P++  
Sbjct: 93  DVPIVANIAGSTVNDYVEVAEAISRVDNVHALELNISCPN---VKEG-GIAFGTVPDVAA 148

Query: 132 DIVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCG------VTFLTSMEEHCTKS 185
            + + ++ V     ++ V ++L  ++   V + Q +E+ G      +  L  M     + 
Sbjct: 149 QLTQEVKRV----STVPVYVKLSPNVSDIVEMAQAVERAGADGLSMINTLLGMRLDLKRR 204

Query: 186 -----------SG----PVDINGLKEVREALSVPMVANGGVKHLNDATTYM 221
                      SG    PV I  + +V +A+S+P++  GG++  +D   +M
Sbjct: 205 TPILANGTGGLSGPAIKPVAIRMIYQVSQAVSIPIIGMGGIQSADDVLEFM 255


>UniRef50_Q73P17 Cluster: Dihydroorotate
           dehydrogenase/oxidoreductase, FAD-binding; n=1;
           Treponema denticola|Rep: Dihydroorotate
           dehydrogenase/oxidoreductase, FAD-binding - Treponema
           denticola
          Length = 591

 Score = 39.1 bits (87), Expect = 0.085
 Identities = 25/106 (23%), Positives = 51/106 (48%), Gaps = 4/106 (3%)

Query: 73  TDFPVIAQFAANNRDDFVDASKLVYPYVDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYD 132
           TD  +    +A+N +DF+   K      D  +LN  CP   A   G+G S+   P I  +
Sbjct: 106 TDSILNVSLSASNPEDFISLLKGFEELADCFELNFSCPHASA---GFGASIGCDPAIAAE 162

Query: 133 IVKGLRNVLPNKFSISVKIRLLNDIKKTVILCQQLEKCGVTFLTSM 178
            VK ++  LP+  ++ + ++L  +++    +   + + G   +T++
Sbjct: 163 YVKIIKKALPD-CAVPIFVKLTPNVEDIGAIASAVIEAGADGITAI 207


>UniRef50_Q090Q9 Cluster: TRNA-dihydrouridine synthase B; n=2;
           Cystobacterineae|Rep: TRNA-dihydrouridine synthase B -
           Stigmatella aurantiaca DW4/3-1
          Length = 369

 Score = 39.1 bits (87), Expect = 0.085
 Identities = 26/107 (24%), Positives = 46/107 (42%), Gaps = 2/107 (1%)

Query: 23  VCAPMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQ-NSKARANEFMTTTTDFPVIAQF 81
           + APM   S+  FR +   + A LC T ++ A    + N +       +   + P   Q 
Sbjct: 46  ILAPMAGVSERPFRVIAFKWGAALCPTELVSAQGLMRANQRTLKYLRFSPEVERPYSLQI 105

Query: 82  AANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKP 127
                +    A+ +   +    +D+N GCP K   K+G G +L+ +P
Sbjct: 106 FGGEPEAMAQAALVGKAHGAQIIDINMGCPVKKVTKNGAGSALMCEP 152


>UniRef50_A6GGZ7 Cluster: Putative uncharacterized protein; n=2;
           Bacteria|Rep: Putative uncharacterized protein -
           Plesiocystis pacifica SIR-1
          Length = 362

 Score = 39.1 bits (87), Expect = 0.085
 Identities = 28/131 (21%), Positives = 56/131 (42%), Gaps = 6/131 (4%)

Query: 25  APMVRYSKVHFRTLVRNFNAD-LCFTPMILADSFCQNSKARANEFMTTTTDFPVIAQFAA 83
           APM+  +  HFR L+R      L +T M+   +     +     +  +  + P+  Q   
Sbjct: 26  APMMDRTDRHFRRLMRLITRHTLLYTEMVTCPAVLHGDREHILGYHPS--EHPLALQLGG 83

Query: 84  NNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLP 142
           ++ +     +++      D V++N GCP        +G  L+  P  + D V  +R  + 
Sbjct: 84  DDPEALAACARIAAELGYDEVNINVGCPSDRVQSGNFGVCLMKDPARVRDCVVAMREAV- 142

Query: 143 NKFSISVKIRL 153
            +  ++VK R+
Sbjct: 143 -ELPVTVKHRI 152


>UniRef50_A5KKR3 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus torques ATCC 27756|Rep: Putative
           uncharacterized protein - Ruminococcus torques ATCC
           27756
          Length = 211

 Score = 39.1 bits (87), Expect = 0.085
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 5/78 (6%)

Query: 78  IAQFAANNRDDFVDASKLVYPY-VDGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKG 136
           + Q   N  +DFV  +K +  Y    ++LN GCP K  +  G G   L+ PE + D+   
Sbjct: 62  VPQILTNCAEDFVQTAKKLEQYGYKEINLNVGCPSKTVVTKGRGAGFLAFPERL-DLF-- 118

Query: 137 LRNVLPN-KFSISVKIRL 153
           L  V  N    ISVK R+
Sbjct: 119 LEEVFQNCPIDISVKTRI 136


>UniRef50_Q4Q669 Cluster: Dihydrouridine synthase (Dus), putative;
           n=3; Leishmania|Rep: Dihydrouridine synthase (Dus),
           putative - Leishmania major
          Length = 661

 Score = 39.1 bits (87), Expect = 0.085
 Identities = 22/55 (40%), Positives = 32/55 (58%), Gaps = 2/55 (3%)

Query: 101 DGVDLNCGCPQKWAMKDGYGCSLLSKPEIIYDIVKGLRNVLPNKFSISVKIRLLN 155
           D VD+N GCPQ  A +  YG  L+   E+I+ IV  L   L  +  ++VKIR+ +
Sbjct: 282 DAVDVNLGCPQGIARRGHYGSFLMEDWELIHTIVHTLHVEL--EVPVTVKIRVFD 334



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 16/41 (39%), Positives = 25/41 (60%)

Query: 26  PMVRYSKVHFRTLVRNFNADLCFTPMILADSFCQNSKARAN 66
           PMV  S++ FR L R + A + +TPM+ A SF   +  R++
Sbjct: 119 PMVDQSELPFRMLCRQYGATVAYTPMLHAKSFADGAVYRSH 159


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.323    0.136    0.412 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 234,893,814
Number of Sequences: 1657284
Number of extensions: 8958832
Number of successful extensions: 18308
Number of sequences better than 10.0: 294
Number of HSP's better than 10.0 without gapping: 189
Number of HSP's successfully gapped in prelim test: 105
Number of HSP's that attempted gapping in prelim test: 17835
Number of HSP's gapped (non-prelim): 340
length of query: 222
length of database: 575,637,011
effective HSP length: 98
effective length of query: 124
effective length of database: 413,223,179
effective search space: 51239674196
effective search space used: 51239674196
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 70 (32.3 bits)

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