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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000352-TA|BGIBMGA000352-PA|IPR001873|Na+ channel,
amiloride-sensitive
         (453 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AF195025-1|AAF19818.1|  549|Homo sapiens acid sensing ion channe...    35   0.51 
AF195024-1|AAF19817.1|  543|Homo sapiens acid sensing ion channe...    35   0.51 
AF095897-1|AAC64188.1|  531|Homo sapiens proton-gated cation cha...    35   0.51 
AF057711-1|AAC62935.1|  531|Homo sapiens proton-gated cation cha...    35   0.51 
AB209421-1|BAD92658.1|  446|Homo sapiens amiloride-sensitive cat...    35   0.51 
AB010575-1|BAA25897.1|  532|Homo sapiens sodium channel protein.       35   0.51 
BC024186-1|AAH24186.1|  365|Homo sapiens zinc finger, MYND-type ...    32   3.6  
AL513331-2|CAH70660.1|  365|Homo sapiens zinc finger, MYND-type ...    32   3.6  
AL445669-1|CAH70745.1|  365|Homo sapiens zinc finger, MYND-type ...    32   3.6  
AK057384-1|BAB71461.1|  365|Homo sapiens protein ( Homo sapiens ...    32   3.6  
U31659-1|AAA84390.1|  677|Homo sapiens TAFII80 protein.                32   4.8  
L25444-1|AAA63643.1|  677|Homo sapiens TAFII70 protein.                32   4.8  
BC018115-1|AAH18115.1|  677|Homo sapiens TAF6 RNA polymerase II,...    32   4.8  
AY149894-1|AAN10295.1|  677|Homo sapiens TAF6 RNA polymerase II,...    32   4.8  
AF451977-1|AAL49758.1| 1431|Homo sapiens cask-interacting protei...    31   6.3  
AB037727-1|BAA92544.1| 1154|Homo sapiens KIAA1306 protein protein.     31   6.3  
AB028987-1|BAA83016.2| 1315|Homo sapiens KIAA1064 protein protein.     31   6.3  
BC017698-1|AAH17698.1|  172|Homo sapiens zinc finger protein 580...    31   8.4  
AL359054-1|CAB94389.1|  259|Homo sapiens LDL induced endothelial...    31   8.4  
AF184939-1|AAD56549.1|  172|Homo sapiens LDL induced EC protein ...    31   8.4  

>AF195025-1|AAF19818.1|  549|Homo sapiens acid sensing ion channel 3
           splice variant c protein.
          Length = 549

 Score = 35.1 bits (77), Expect = 0.51
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 65  AEHAAEYLAEPGLVGENENNVPEPARDSKEAVFKVVRHCETLFYDCVWKGDSEECC-DLL 123
           AEHAA +L   G        +P P  D  +   +     + +  DC ++G  + C  +  
Sbjct: 120 AEHAA-FLRALGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRG--QPCGPENF 176

Query: 124 IPVFTEMGFCYAFNS 138
             +FT MG CY FNS
Sbjct: 177 TTIFTRMGKCYTFNS 191


>AF195024-1|AAF19817.1|  543|Homo sapiens acid sensing ion channel 3
           splice variant b protein.
          Length = 543

 Score = 35.1 bits (77), Expect = 0.51
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 65  AEHAAEYLAEPGLVGENENNVPEPARDSKEAVFKVVRHCETLFYDCVWKGDSEECC-DLL 123
           AEHAA +L   G        +P P  D  +   +     + +  DC ++G  + C  +  
Sbjct: 120 AEHAA-FLRALGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRG--QPCGPENF 176

Query: 124 IPVFTEMGFCYAFNS 138
             +FT MG CY FNS
Sbjct: 177 TTIFTRMGKCYTFNS 191


>AF095897-1|AAC64188.1|  531|Homo sapiens proton-gated cation
           channel ASIC3 protein.
          Length = 531

 Score = 35.1 bits (77), Expect = 0.51
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 65  AEHAAEYLAEPGLVGENENNVPEPARDSKEAVFKVVRHCETLFYDCVWKGDSEECC-DLL 123
           AEHAA +L   G        +P P  D  +   +     + +  DC ++G  + C  +  
Sbjct: 120 AEHAA-FLRALGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRG--QPCGPENF 176

Query: 124 IPVFTEMGFCYAFNS 138
             +FT MG CY FNS
Sbjct: 177 TTIFTRMGKCYTFNS 191


>AF057711-1|AAC62935.1|  531|Homo sapiens proton-gated cation
           channel subunit protein.
          Length = 531

 Score = 35.1 bits (77), Expect = 0.51
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 65  AEHAAEYLAEPGLVGENENNVPEPARDSKEAVFKVVRHCETLFYDCVWKGDSEECC-DLL 123
           AEHAA +L   G        +P P  D  +   +     + +  DC ++G  + C  +  
Sbjct: 120 AEHAA-FLRALGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRG--QPCGPENF 176

Query: 124 IPVFTEMGFCYAFNS 138
             +FT MG CY FNS
Sbjct: 177 TTIFTRMGKCYTFNS 191


>AB209421-1|BAD92658.1|  446|Homo sapiens amiloride-sensitive cation
           channel 3 isoform c variant protein.
          Length = 446

 Score = 35.1 bits (77), Expect = 0.51
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 65  AEHAAEYLAEPGLVGENENNVPEPARDSKEAVFKVVRHCETLFYDCVWKGDSEECC-DLL 123
           AEHAA +L   G        +P P  D  +   +     + +  DC ++G  + C  +  
Sbjct: 159 AEHAA-FLRALGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRG--QPCGPENF 215

Query: 124 IPVFTEMGFCYAFNS 138
             +FT MG CY FNS
Sbjct: 216 TTIFTRMGKCYTFNS 230


>AB010575-1|BAA25897.1|  532|Homo sapiens sodium channel protein.
          Length = 532

 Score = 35.1 bits (77), Expect = 0.51
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 65  AEHAAEYLAEPGLVGENENNVPEPARDSKEAVFKVVRHCETLFYDCVWKGDSEECC-DLL 123
           AEHAA +L   G        +P P  D  +   +     + +  DC ++G  + C  +  
Sbjct: 120 AEHAA-FLRALGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRG--QPCGPENF 176

Query: 124 IPVFTEMGFCYAFNS 138
             +FT MG CY FNS
Sbjct: 177 TTIFTRMGKCYTFNS 191


>BC024186-1|AAH24186.1|  365|Homo sapiens zinc finger, MYND-type
           containing 12 protein.
          Length = 365

 Score = 32.3 bits (70), Expect = 3.6
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 4/76 (5%)

Query: 95  AVFKVVRHCETLFYDCVWKGDSEECCDLLIPVFTEMGFCYAFNSRHAEKIWPWQSQAQQE 154
           A   V  +C  +     W    E+ C LLIP+ T M F   +NS    +    Q Q +Q+
Sbjct: 29  AACTVTYYCGVVHQKADWDSIHEKICQLLIPLRTSMPF---YNSEEERQHGLQQLQQRQK 85

Query: 155 QFIEAFIHETDAKWSF 170
             IE F +    K+ F
Sbjct: 86  YLIE-FCYTIAQKYLF 100


>AL513331-2|CAH70660.1|  365|Homo sapiens zinc finger, MYND-type
           containing 12 protein.
          Length = 365

 Score = 32.3 bits (70), Expect = 3.6
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 4/76 (5%)

Query: 95  AVFKVVRHCETLFYDCVWKGDSEECCDLLIPVFTEMGFCYAFNSRHAEKIWPWQSQAQQE 154
           A   V  +C  +     W    E+ C LLIP+ T M F   +NS    +    Q Q +Q+
Sbjct: 29  AACTVTYYCGVVHQKADWDSIHEKICQLLIPLRTSMPF---YNSEEERQHGLQQLQQRQK 85

Query: 155 QFIEAFIHETDAKWSF 170
             IE F +    K+ F
Sbjct: 86  YLIE-FCYTIAQKYLF 100


>AL445669-1|CAH70745.1|  365|Homo sapiens zinc finger, MYND-type
           containing 12 protein.
          Length = 365

 Score = 32.3 bits (70), Expect = 3.6
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 4/76 (5%)

Query: 95  AVFKVVRHCETLFYDCVWKGDSEECCDLLIPVFTEMGFCYAFNSRHAEKIWPWQSQAQQE 154
           A   V  +C  +     W    E+ C LLIP+ T M F   +NS    +    Q Q +Q+
Sbjct: 29  AACTVTYYCGVVHQKADWDSIHEKICQLLIPLRTSMPF---YNSEEERQHGLQQLQQRQK 85

Query: 155 QFIEAFIHETDAKWSF 170
             IE F +    K+ F
Sbjct: 86  YLIE-FCYTIAQKYLF 100


>AK057384-1|BAB71461.1|  365|Homo sapiens protein ( Homo sapiens
           cDNA FLJ32822 fis, clone TESTI2003037. ).
          Length = 365

 Score = 32.3 bits (70), Expect = 3.6
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 4/76 (5%)

Query: 95  AVFKVVRHCETLFYDCVWKGDSEECCDLLIPVFTEMGFCYAFNSRHAEKIWPWQSQAQQE 154
           A   V  +C  +     W    E+ C LLIP+ T M F   +NS    +    Q Q +Q+
Sbjct: 29  AACTVTYYCGVVHQKADWDSIHEKICQLLIPLRTSMPF---YNSEEERQHGLQQLQQRQK 85

Query: 155 QFIEAFIHETDAKWSF 170
             IE F +    K+ F
Sbjct: 86  YLIE-FCYTIAQKYLF 100


>U31659-1|AAA84390.1|  677|Homo sapiens TAFII80 protein.
          Length = 677

 Score = 31.9 bits (69), Expect = 4.8
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 9/73 (12%)

Query: 382 LRACCAAVRDADQLRRERAERLAQPKPPHNLSLIPWW--KEP---PIPGSVR-PI--LVR 433
           ++A   A   A Q+ R     + QP+P   LS  P    + P    +PGS+  P+  LV 
Sbjct: 464 VKARAQAALQAQQVNRTTLT-ITQPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVS 522

Query: 434 AKDSMPPQYSPPP 446
           A+ + PPQ SPPP
Sbjct: 523 ARAAAPPQPSPPP 535


>L25444-1|AAA63643.1|  677|Homo sapiens TAFII70 protein.
          Length = 677

 Score = 31.9 bits (69), Expect = 4.8
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 9/73 (12%)

Query: 382 LRACCAAVRDADQLRRERAERLAQPKPPHNLSLIPWW--KEP---PIPGSVR-PI--LVR 433
           ++A   A   A Q+ R     + QP+P   LS  P    + P    +PGS+  P+  LV 
Sbjct: 464 VKARAQAALQAQQVNRTTLT-ITQPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVS 522

Query: 434 AKDSMPPQYSPPP 446
           A+ + PPQ SPPP
Sbjct: 523 ARAAAPPQPSPPP 535


>BC018115-1|AAH18115.1|  677|Homo sapiens TAF6 RNA polymerase II,
           TATA box binding protein (TBP)-associated factor, 80kDa
           protein.
          Length = 677

 Score = 31.9 bits (69), Expect = 4.8
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 9/73 (12%)

Query: 382 LRACCAAVRDADQLRRERAERLAQPKPPHNLSLIPWW--KEP---PIPGSVR-PI--LVR 433
           ++A   A   A Q+ R     + QP+P   LS  P    + P    +PGS+  P+  LV 
Sbjct: 464 VKARAQAALQAQQVNRTTLT-ITQPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVS 522

Query: 434 AKDSMPPQYSPPP 446
           A+ + PPQ SPPP
Sbjct: 523 ARAAAPPQPSPPP 535


>AY149894-1|AAN10295.1|  677|Homo sapiens TAF6 RNA polymerase II,
           TATA box binding protein (TBP)-associated factor, 80kDa
           protein.
          Length = 677

 Score = 31.9 bits (69), Expect = 4.8
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 9/73 (12%)

Query: 382 LRACCAAVRDADQLRRERAERLAQPKPPHNLSLIPWW--KEP---PIPGSVR-PI--LVR 433
           ++A   A   A Q+ R     + QP+P   LS  P    + P    +PGS+  P+  LV 
Sbjct: 464 VKARAQAALQAQQVNRTTLT-ITQPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVS 522

Query: 434 AKDSMPPQYSPPP 446
           A+ + PPQ SPPP
Sbjct: 523 ARAAAPPQPSPPP 535


>AF451977-1|AAL49758.1| 1431|Homo sapiens cask-interacting protein 1
            protein.
          Length = 1431

 Score = 31.5 bits (68), Expect = 6.3
 Identities = 20/52 (38%), Positives = 24/52 (46%), Gaps = 1/52 (1%)

Query: 403  LAQPKPPHNLSLIPWWKEPPIPGSVRPILVRAKDSMPP-QYSPPPGYTTYLP 453
            L QP P    S  P  K+ P+PG   P + RA  + PP    PPP  T   P
Sbjct: 1232 LTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKP 1283


>AB037727-1|BAA92544.1| 1154|Homo sapiens KIAA1306 protein protein.
          Length = 1154

 Score = 31.5 bits (68), Expect = 6.3
 Identities = 20/52 (38%), Positives = 24/52 (46%), Gaps = 1/52 (1%)

Query: 403  LAQPKPPHNLSLIPWWKEPPIPGSVRPILVRAKDSMPP-QYSPPPGYTTYLP 453
            L QP P    S  P  K+ P+PG   P + RA  + PP    PPP  T   P
Sbjct: 955  LTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKP 1006


>AB028987-1|BAA83016.2| 1315|Homo sapiens KIAA1064 protein protein.
          Length = 1315

 Score = 31.5 bits (68), Expect = 6.3
 Identities = 17/57 (29%), Positives = 27/57 (47%), Gaps = 2/57 (3%)

Query: 390 RDADQLRRERAERLAQPKPPHNLSLIPWWKEPPIPGSVRPILVRAKDSMPPQYSPPP 446
           ++ ++L+++    L  PKPP  + L+P    PP P +      R     PP   PPP
Sbjct: 506 KEVEELKKQGINPL--PKPPPGVGLLPTPPRPPGPQAPTSPNGRPMQGGPPPPPPPP 560


>BC017698-1|AAH17698.1|  172|Homo sapiens zinc finger protein 580
           protein.
          Length = 172

 Score = 31.1 bits (67), Expect = 8.4
 Identities = 15/37 (40%), Positives = 18/37 (48%)

Query: 380 FTLRACCAAVRDADQLRRERAERLAQPKPPHNLSLIP 416
           FT  AC  A + +  L R RA   A+  PPH   L P
Sbjct: 120 FTCGACGKAFKRSSHLSRHRATHRARAGPPHTCPLCP 156


>AL359054-1|CAB94389.1|  259|Homo sapiens LDL induced endothelial
           cell protein protein.
          Length = 259

 Score = 31.1 bits (67), Expect = 8.4
 Identities = 15/37 (40%), Positives = 18/37 (48%)

Query: 380 FTLRACCAAVRDADQLRRERAERLAQPKPPHNLSLIP 416
           FT  AC  A + +  L R RA   A+  PPH   L P
Sbjct: 207 FTCGACGKAFKRSSHLSRHRATHRARAGPPHTCPLCP 243


>AF184939-1|AAD56549.1|  172|Homo sapiens LDL induced EC protein
           protein.
          Length = 172

 Score = 31.1 bits (67), Expect = 8.4
 Identities = 15/37 (40%), Positives = 18/37 (48%)

Query: 380 FTLRACCAAVRDADQLRRERAERLAQPKPPHNLSLIP 416
           FT  AC  A + +  L R RA   A+  PPH   L P
Sbjct: 120 FTCGACGKAFKRSSHLSRHRATHRARAGPPHTCPLCP 156


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.320    0.134    0.433 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 71,819,685
Number of Sequences: 224733
Number of extensions: 3103594
Number of successful extensions: 6678
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 6662
Number of HSP's gapped (non-prelim): 31
length of query: 453
length of database: 73,234,838
effective HSP length: 92
effective length of query: 361
effective length of database: 52,559,402
effective search space: 18973944122
effective search space used: 18973944122
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 67 (31.1 bits)

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