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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000307-TA|BGIBMGA000307-PA|IPR000834|Peptidase M14,
carboxypeptidase A, IPR008969|Carboxypeptidase regulatory region
         (483 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X51405-1|CAA35767.1|  476|Homo sapiens protein ( Human mRNA for ...   387   e-107
BC053612-1|AAH53612.1|  476|Homo sapiens carboxypeptidase E prot...   387   e-107
BC033866-1|AAH33866.1|  476|Homo sapiens carboxypeptidase E prot...   387   e-107
AB006898-1|BAA86053.1|  476|Homo sapiens carboxypeptidase E prot...   385   e-106
X14329-1|CAA32507.1|  458|Homo sapiens protein ( Human mRNA for ...   358   3e-98
BC027897-1|AAH27897.1|  458|Homo sapiens carboxypeptidase N, pol...   358   3e-98
AL441886-3|CAI13078.1|  458|Homo sapiens carboxypeptidase N, pol...   358   3e-98
BC080539-1|AAH80539.1|  652|Homo sapiens carboxypeptidase Z prot...   343   1e-93
U83411-1|AAB58911.1|  641|Homo sapiens carboxypeptidase Z precur...   341   3e-93
BC045549-1|AAH45549.1| 1380|Homo sapiens carboxypeptidase D prot...   325   2e-88
U65090-1|AAC51775.2| 1380|Homo sapiens carboxypeptidase D protein.    323   7e-88
D85390-1|BAA33370.1| 1380|Homo sapiens gp180-carboxypeptidase D-...   323   7e-88
BC063430-1|AAH63430.1|  734|Homo sapiens carboxypeptidase X (M14...   323   7e-88
BC051702-1|AAH51702.1| 1380|Homo sapiens carboxypeptidase D prot...   323   7e-88
BC045624-1|AAH45624.1| 1380|Homo sapiens carboxypeptidase D prot...   323   7e-88
AY358956-1|AAQ89315.1|  734|Homo sapiens CPXM protein.                323   7e-88
AL035460-3|CAB82246.1|  734|Homo sapiens carboxypeptidase X (M14...   323   7e-88
AK027661-1|BAB55275.1|  734|Homo sapiens protein ( Homo sapiens ...   322   1e-87
BC036789-1|AAH36789.2|  756|Homo sapiens carboxypeptidase X (M14...   318   3e-86
AY358565-1|AAQ88928.1|  756|Homo sapiens carboxypeptidase Hlo pr...   318   3e-86
AK075508-1|BAC11661.1|  430|Homo sapiens protein ( Homo sapiens ...   315   3e-85
J04970-1|AAA35651.2|  443|Homo sapiens carboxypeptidase M precur...   280   7e-75
BC022276-1|AAH22276.1|  443|Homo sapiens carboxypeptidase M prot...   280   7e-75
AF368463-1|AAK69717.1|  443|Homo sapiens carboxypeptidase M prot...   280   7e-75
AF262947-1|AAG47641.1|  443|Homo sapiens carboxypeptidase M prot...   280   7e-75
D86479-1|BAA13094.1|  845|Homo sapiens AEBP1 protein.                 275   3e-73
BC038588-1|AAH38588.1| 1158|Homo sapiens AE binding protein 1 pr...   275   3e-73
AF053944-1|AAC25585.1| 1158|Homo sapiens aortic carboxypeptidase...   275   3e-73
AB209744-1|BAD92981.1| 1172|Homo sapiens adipocyte enhancer bind...   275   3e-73
AK127541-1|BAC87026.1|  733|Homo sapiens protein ( Homo sapiens ...   272   2e-72
AL441886-2|CAI13077.1|  204|Homo sapiens carboxypeptidase N, pol...   174   5e-43
BC027623-1|AAH27623.1|  224|Homo sapiens CPXM2 protein protein.       153   2e-36
AK075527-1|BAC11672.1|  477|Homo sapiens protein ( Homo sapiens ...   142   2e-33
AK056317-1|BAB71147.1|  364|Homo sapiens protein ( Homo sapiens ...   139   2e-32
BC052289-1|AAH52289.1|  421|Homo sapiens CPA4 protein protein.         46   3e-04
AY358699-1|AAQ89062.1|  421|Homo sapiens CPA4 protein.                 46   3e-04
AF095719-1|AAF23230.1|  421|Homo sapiens carboxypeptidase A3 pro...    46   3e-04
U19977-1|AAA74425.1|  417|Homo sapiens preprocarboxypeptidase A2...    34   1.3  
U11700-1|AAA92667.1| 1465|Homo sapiens copper transporting ATPas...    34   1.3  
U03464-1|AAB52902.1| 1465|Homo sapiens ATP7B protein.                  34   1.3  
L25591-2|AAA79212.1|  762|Homo sapiens protein ( Homo sapiens (P...    34   1.3  
DQ015922-1|AAY41166.1| 1354|Homo sapiens Wilson's disease protei...    34   1.3  
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq...    34   1.3  
BT007403-1|AAP36067.1|  417|Homo sapiens carboxypeptidase A2 (pa...    34   1.3  
BC117200-1|AAI17201.1| 1035|Homo sapiens ATP7B protein protein.        34   1.3  
BC015140-1|AAH15140.1|  417|Homo sapiens carboxypeptidase A2 (pa...    34   1.3  
BC014571-1|AAH14571.1|  417|Homo sapiens carboxypeptidase A2 (pa...    34   1.3  
BC007009-1|AAH07009.1|  417|Homo sapiens carboxypeptidase A2 (pa...    34   1.3  
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq...    34   1.3  
AL162377-2|CAI13428.1| 1465|Homo sapiens Atp7b protein.                34   1.3  
AL139082-1|CAI12888.1| 1465|Homo sapiens Atp7b protein.                34   1.3  
AL138821-2|CAI13743.1| 1465|Homo sapiens Atp7b protein.                34   1.3  
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq...    34   1.3  
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq...    34   1.3  
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq...    34   1.3  
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq...    34   1.3  
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq...    34   1.3  
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq...    34   1.3  
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.            34   1.3  
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.           34   1.3  
AB209461-1|BAD92698.1|  662|Homo sapiens ATPase, Cu++ transporti...    34   1.3  

>X51405-1|CAA35767.1|  476|Homo sapiens protein ( Human mRNA for
           carboxypeptidase E (EC 3.4.17.10). ).
          Length = 476

 Score =  387 bits (952), Expect = e-107
 Identities = 205/420 (48%), Positives = 273/420 (65%), Gaps = 24/420 (5%)

Query: 21  WKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKY 80
           +++H   EL   L  V   C  I+RIY +   S     L VIE +  PG H P  PE KY
Sbjct: 51  FEYHRYPELREALVSVWLQCTAISRIYTVGR-SFEGRELLVIELSDNPGVHEPGEPEFKY 109

Query: 81  IGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDTG 140
           IGN+HGNE +GRELL+ LA YLC++Y+K +  I  LI +TRIH++PS+NPDG++ A    
Sbjct: 110 IGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQP 169

Query: 141 G--KDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQL---SAPLEPE 195
           G  KD+ +GR+N   +DLNRNFPDLD I +  E++G   NNHLLK++ ++   +  L PE
Sbjct: 170 GELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEG-GPNNHLLKNMKKIVDQNTKLAPE 228

Query: 196 TRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFKELAMTYAL 255
           T+AV+ WIM  PFVLSA +HGGDLVANYPYDE+++G SA EYS+SPDD  F+ LA  Y+ 
Sbjct: 229 TKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSG-SAHEYSSSPDDAIFQSLARAYSS 287

Query: 256 AHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLE 315
            +  M+ P R  C   + DD S+      G TNG AWYS+ GGMQDFNYL++N FEIT+E
Sbjct: 288 FNPAMSDPNRPPCRK-NDDDSSF----VDGTTNGGAWYSVPGGMQDFNYLSSNCFEITVE 342

Query: 316 LGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGF-IPNAIISVVNCTGSV 374
           L CEK+P  E L+T W  N+ +L+ YL + H GVKG V D +G  I NA ISV       
Sbjct: 343 LSCEKFPPEETLKTYWEDNKNSLISYLEQIHRGVKGFVRDLQGNPIANATISV------- 395

Query: 375 TKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSAIILDFRLEEF 434
            + I HDVT+   GDY+RLL PG Y++TA+  G+   ++ V+VP +  + +  DF LE F
Sbjct: 396 -EGIDHDVTSAKDGDYWRLLIPGNYKLTASAPGYLAITKKVAVPYSPAAGV--DFELESF 452


>BC053612-1|AAH53612.1|  476|Homo sapiens carboxypeptidase E
           protein.
          Length = 476

 Score =  387 bits (952), Expect = e-107
 Identities = 205/420 (48%), Positives = 273/420 (65%), Gaps = 24/420 (5%)

Query: 21  WKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKY 80
           +++H   EL   L  V   C  I+RIY +   S     L VIE +  PG H P  PE KY
Sbjct: 51  FEYHRYPELREALVSVWLQCTAISRIYTVGR-SFEGRELLVIELSDNPGVHEPGEPEFKY 109

Query: 81  IGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDTG 140
           IGN+HGNE +GRELL+ LA YLC++Y+K +  I  LI +TRIH++PS+NPDG++ A    
Sbjct: 110 IGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQP 169

Query: 141 G--KDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQL---SAPLEPE 195
           G  KD+ +GR+N   +DLNRNFPDLD I +  E++G   NNHLLK++ ++   +  L PE
Sbjct: 170 GELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEG-GPNNHLLKNMKKIVDQNTKLAPE 228

Query: 196 TRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFKELAMTYAL 255
           T+AV+ WIM  PFVLSA +HGGDLVANYPYDE+++G SA EYS+SPDD  F+ LA  Y+ 
Sbjct: 229 TKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSG-SAHEYSSSPDDAIFQSLARAYSS 287

Query: 256 AHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLE 315
            +  M+ P R  C   + DD S+      G TNG AWYS+ GGMQDFNYL++N FEIT+E
Sbjct: 288 FNPAMSDPNRPPCRK-NDDDSSF----VDGTTNGGAWYSVPGGMQDFNYLSSNCFEITVE 342

Query: 316 LGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGF-IPNAIISVVNCTGSV 374
           L CEK+P  E L+T W  N+ +L+ YL + H GVKG V D +G  I NA ISV       
Sbjct: 343 LSCEKFPPEETLKTYWEDNKNSLISYLEQIHRGVKGFVRDLQGNPIANATISV------- 395

Query: 375 TKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSAIILDFRLEEF 434
            + I HDVT+   GDY+RLL PG Y++TA+  G+   ++ V+VP +  + +  DF LE F
Sbjct: 396 -EGIDHDVTSAKDGDYWRLLIPGNYKLTASAPGYLAITKKVAVPYSPAAGV--DFELESF 452


>BC033866-1|AAH33866.1|  476|Homo sapiens carboxypeptidase E
           protein.
          Length = 476

 Score =  387 bits (952), Expect = e-107
 Identities = 205/420 (48%), Positives = 273/420 (65%), Gaps = 24/420 (5%)

Query: 21  WKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKY 80
           +++H   EL   L  V   C  I+RIY +   S     L VIE +  PG H P  PE KY
Sbjct: 51  FEYHRYPELREALVSVWLQCTAISRIYTVGR-SFEGRELLVIELSDNPGVHEPGEPEFKY 109

Query: 81  IGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDTG 140
           IGN+HGNE +GRELL+ LA YLC++Y+K +  I  LI +TRIH++PS+NPDG++ A    
Sbjct: 110 IGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQP 169

Query: 141 G--KDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQL---SAPLEPE 195
           G  KD+ +GR+N   +DLNRNFPDLD I +  E++G   NNHLLK++ ++   +  L PE
Sbjct: 170 GELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEG-GPNNHLLKNMKKIVDQNTKLAPE 228

Query: 196 TRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFKELAMTYAL 255
           T+AV+ WIM  PFVLSA +HGGDLVANYPYDE+++G SA EYS+SPDD  F+ LA  Y+ 
Sbjct: 229 TKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSG-SAHEYSSSPDDAIFQSLARAYSS 287

Query: 256 AHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLE 315
            +  M+ P R  C   + DD S+      G TNG AWYS+ GGMQDFNYL++N FEIT+E
Sbjct: 288 FNPAMSDPNRPPCRK-NDDDSSF----VDGTTNGGAWYSVPGGMQDFNYLSSNCFEITVE 342

Query: 316 LGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGF-IPNAIISVVNCTGSV 374
           L CEK+P  E L+T W  N+ +L+ YL + H GVKG V D +G  I NA ISV       
Sbjct: 343 LSCEKFPPEETLKTYWEDNKNSLISYLEQIHRGVKGFVRDLQGNPIANATISV------- 395

Query: 375 TKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSAIILDFRLEEF 434
            + I HDVT+   GDY+RLL PG Y++TA+  G+   ++ V+VP +  + +  DF LE F
Sbjct: 396 -EGIDHDVTSAKDGDYWRLLIPGNYKLTASAPGYLAITKKVAVPYSPAAGV--DFELESF 452


>AB006898-1|BAA86053.1|  476|Homo sapiens carboxypeptidase E
           protein.
          Length = 476

 Score =  385 bits (947), Expect = e-106
 Identities = 204/420 (48%), Positives = 272/420 (64%), Gaps = 24/420 (5%)

Query: 21  WKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKY 80
           +++H   EL   L  V   C  I+RIY +   S     L VIE +  PG H P  PE KY
Sbjct: 51  FEYHRYPELREALVSVWLQCTAISRIYTVGR-SFEGRELLVIELSDNPGVHEPGEPEFKY 109

Query: 81  IGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDTG 140
           IGN+HGNE +GRELL+ LA YLC++Y+K +  I  LI +TRIH++PS+NPDG++ A    
Sbjct: 110 IGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQP 169

Query: 141 G--KDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQL---SAPLEPE 195
           G  KD+ +GR+N   +DLNRNFPDLD I +  E++G   NNHLLK++ ++   +  L PE
Sbjct: 170 GELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEG-GPNNHLLKNMKKIVDQNTKLAPE 228

Query: 196 TRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFKELAMTYAL 255
           T+AV+ WIM  PFVLSA +HGGDLVANYPYDE+++G SA EYS+SPDD  F+ LA  Y+ 
Sbjct: 229 TKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSG-SAHEYSSSPDDAIFQSLARAYSS 287

Query: 256 AHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLE 315
            +  M+ P R  C   + DD S+      G TNG AWYS+ GGMQDFNYL++N FEIT+E
Sbjct: 288 FNPAMSDPNRPPCRK-NDDDSSF----VDGTTNGGAWYSVPGGMQDFNYLSSNCFEITVE 342

Query: 316 LGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGF-IPNAIISVVNCTGSV 374
           L CEK+P  E L+T W  N+ +L+ YL + H GVKG V D +G  I N  ISV       
Sbjct: 343 LSCEKFPPEETLKTYWEDNKNSLISYLEQIHRGVKGFVRDLQGNPIANRTISV------- 395

Query: 375 TKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSAIILDFRLEEF 434
            + I HDVT+   GDY+RLL PG Y++TA+  G+   ++ V+VP +  + +  DF LE F
Sbjct: 396 -EGIDHDVTSAKDGDYWRLLIPGNYKLTASAPGYLAITKKVAVPYSPAAGV--DFELESF 452


>X14329-1|CAA32507.1|  458|Homo sapiens protein ( Human mRNA for
           carboxypeptidase N small subunit (EC 3.4.17.3). ).
          Length = 458

 Score =  358 bits (880), Expect = 3e-98
 Identities = 194/420 (46%), Positives = 261/420 (62%), Gaps = 32/420 (7%)

Query: 6   FVCFSLLLTVSAEFQWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFA 65
           F+   LL  + A   ++HH  ++L   L +V N CP ITR+Y++   SV    LYV+EF+
Sbjct: 8   FLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGR-SVEGRHLYVLEFS 66

Query: 66  QVPGFHRPYIPEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLL 125
             PG H P  PE KY+GN+HGNE LGREL+L L+ +LC+++R  +  I  LI +TRIH+L
Sbjct: 67  DHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHIL 126

Query: 126 PSMNPDGWQLATDTGGK--DYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHL-L 182
           PSMNPDG+++A   G     YL+GR N + VDLNRNFPDL+   +  E+ G   N+HL L
Sbjct: 127 PSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYG-GPNHHLPL 185

Query: 183 KDLTQLSAPLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDES----KTGASAAEYS 238
            D     + +EPETRAV+RW+ S  FVLSA +HGG +VANYPYD+S      G      +
Sbjct: 186 PD--NWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTAST 243

Query: 239 ASPDDETFKELAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGG 298
            +PDD+ F++LA  Y+ AH  M      G +               G+TNGA+WYSL  G
Sbjct: 244 PTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPD------------GITNGASWYSLSKG 291

Query: 299 MQDFNYLATNAFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSK- 357
           MQDFNYL TN FEITLEL C+K+P  E L+ EW  NREAL+++L + H G+KG+V D   
Sbjct: 292 MQDFNYLHTNCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENY 351

Query: 358 GFIPNAIISVVNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSV 417
             + NA+ISV          I HDVT+G +GDY+RLL PG Y ++AT  G+   +  V+V
Sbjct: 352 NNLANAVISV--------SGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTV 403


>BC027897-1|AAH27897.1|  458|Homo sapiens carboxypeptidase N,
           polypeptide 1 protein.
          Length = 458

 Score =  358 bits (880), Expect = 3e-98
 Identities = 194/420 (46%), Positives = 261/420 (62%), Gaps = 32/420 (7%)

Query: 6   FVCFSLLLTVSAEFQWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFA 65
           F+   LL  + A   ++HH  ++L   L +V N CP ITR+Y++   SV    LYV+EF+
Sbjct: 8   FLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGR-SVEGRHLYVLEFS 66

Query: 66  QVPGFHRPYIPEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLL 125
             PG H P  PE KY+GN+HGNE LGREL+L L+ +LC+++R  +  I  LI +TRIH+L
Sbjct: 67  DHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHIL 126

Query: 126 PSMNPDGWQLATDTGGK--DYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHL-L 182
           PSMNPDG+++A   G     YL+GR N + VDLNRNFPDL+   +  E+ G   N+HL L
Sbjct: 127 PSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYG-GPNHHLPL 185

Query: 183 KDLTQLSAPLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDES----KTGASAAEYS 238
            D     + +EPETRAV+RW+ S  FVLSA +HGG +VANYPYD+S      G      +
Sbjct: 186 PD--NWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTAST 243

Query: 239 ASPDDETFKELAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGG 298
            +PDD+ F++LA  Y+ AH  M      G +               G+TNGA+WYSL  G
Sbjct: 244 PTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPD------------GITNGASWYSLSKG 291

Query: 299 MQDFNYLATNAFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSK- 357
           MQDFNYL TN FEITLEL C+K+P  E L+ EW  NREAL+++L + H G+KG+V D   
Sbjct: 292 MQDFNYLHTNCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENY 351

Query: 358 GFIPNAIISVVNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSV 417
             + NA+ISV          I HDVT+G +GDY+RLL PG Y ++AT  G+   +  V+V
Sbjct: 352 NNLANAVISV--------SGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTV 403


>AL441886-3|CAI13078.1|  458|Homo sapiens carboxypeptidase N,
           polypeptide 1, 50kD protein.
          Length = 458

 Score =  358 bits (880), Expect = 3e-98
 Identities = 194/420 (46%), Positives = 261/420 (62%), Gaps = 32/420 (7%)

Query: 6   FVCFSLLLTVSAEFQWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFA 65
           F+   LL  + A   ++HH  ++L   L +V N CP ITR+Y++   SV    LYV+EF+
Sbjct: 8   FLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGR-SVEGRHLYVLEFS 66

Query: 66  QVPGFHRPYIPEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLL 125
             PG H P  PE KY+GN+HGNE LGREL+L L+ +LC+++R  +  I  LI +TRIH+L
Sbjct: 67  DHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHIL 126

Query: 126 PSMNPDGWQLATDTGGK--DYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHL-L 182
           PSMNPDG+++A   G     YL+GR N + VDLNRNFPDL+   +  E+ G   N+HL L
Sbjct: 127 PSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYG-GPNHHLPL 185

Query: 183 KDLTQLSAPLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDES----KTGASAAEYS 238
            D     + +EPETRAV+RW+ S  FVLSA +HGG +VANYPYD+S      G      +
Sbjct: 186 PD--NWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTAST 243

Query: 239 ASPDDETFKELAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGG 298
            +PDD+ F++LA  Y+ AH  M      G +               G+TNGA+WYSL  G
Sbjct: 244 PTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPD------------GITNGASWYSLSKG 291

Query: 299 MQDFNYLATNAFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSK- 357
           MQDFNYL TN FEITLEL C+K+P  E L+ EW  NREAL+++L + H G+KG+V D   
Sbjct: 292 MQDFNYLHTNCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENY 351

Query: 358 GFIPNAIISVVNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSV 417
             + NA+ISV          I HDVT+G +GDY+RLL PG Y ++AT  G+   +  V+V
Sbjct: 352 NNLANAVISV--------SGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTV 403


>BC080539-1|AAH80539.1|  652|Homo sapiens carboxypeptidase Z
           protein.
          Length = 652

 Score =  343 bits (842), Expect = 1e-93
 Identities = 183/437 (41%), Positives = 253/437 (57%), Gaps = 21/437 (4%)

Query: 20  QWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAK 79
           ++ HH+  ++  VL+   + C ++ R Y++   S     L VIEF+  PG H    PE K
Sbjct: 184 RFSHHSYAQMVRVLRRTASRCAHVARTYSIGR-SFDGRELLVIEFSSRPGQHELMEPEVK 242

Query: 80  YIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDT 139
            IGNIHGNEV GRE+L+ LA YLC +Y   +P I+ L+  TRIHLLPSMNPDG+++A   
Sbjct: 243 LIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAE 302

Query: 140 GG--KDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQLSAPLEPETR 197
           G     +  GR N   +DLNRNFPDL +  +       + ++H+          + PET+
Sbjct: 303 GAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETK 362

Query: 198 AVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFKELAMTYALAH 257
           A+M+W+ + PFVLSA++HGGDLV +YP+D SK       +S +PD++ FK L+  YA  H
Sbjct: 363 AIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYADVH 422

Query: 258 ADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLELG 317
             M   +   C          NF K+G + NGA WYS  GGM DFNYL TN FEIT+ELG
Sbjct: 423 PMMMDRSENRC--------GGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELG 474

Query: 318 CEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGF-IPNAIISVVNCTGSVTK 376
           C K+P  E L T W  N+E+L+ ++   H G+KGVV+D  G  + NA ISV        K
Sbjct: 475 CVKFPPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISV--------K 526

Query: 377 PIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSAIILDFRLEEF-Q 435
            IRHD+TT P GDY+RLL PG + + A   G+ +  + V +P   K A  +DF L+    
Sbjct: 527 GIRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFILQPLGM 586

Query: 436 GKTNWLQDLSSFGVYSP 452
           G  N++  L   G + P
Sbjct: 587 GPKNFIHGLRRTGPHDP 603


>U83411-1|AAB58911.1|  641|Homo sapiens carboxypeptidase Z precursor
           protein.
          Length = 641

 Score =  341 bits (838), Expect = 3e-93
 Identities = 182/437 (41%), Positives = 253/437 (57%), Gaps = 21/437 (4%)

Query: 20  QWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAK 79
           ++ HH+  ++  VL+   + C ++ R Y++   S     L VIEF+  PG H    PE K
Sbjct: 173 RFSHHSYAQMVRVLRRTASRCAHVARTYSIGR-SFDGRELLVIEFSSRPGQHELMEPEVK 231

Query: 80  YIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDT 139
            IGNIHGNEV GRE+L+ LA YLC +Y   +P I+ L+  TRIHLLPS+NPDG+++A   
Sbjct: 232 LIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSINPDGYEVAAAE 291

Query: 140 GG--KDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQLSAPLEPETR 197
           G     +  GR N   +DLNRNFPDL +  +       + ++H+          + PET+
Sbjct: 292 GAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETK 351

Query: 198 AVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFKELAMTYALAH 257
           A+M+W+ + PFVLSA++HGGDLV +YP+D SK       +S +PD++ FK L+  YA  H
Sbjct: 352 AIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYADVH 411

Query: 258 ADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLELG 317
             M   +   C          NF K+G + NGA WYS  GGM DFNYL TN FEIT+ELG
Sbjct: 412 PMMMDRSENRC--------GGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELG 463

Query: 318 CEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGF-IPNAIISVVNCTGSVTK 376
           C K+P  E L T W  N+E+L+ ++   H G+KGVV+D  G  + NA ISV        K
Sbjct: 464 CVKFPPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISV--------K 515

Query: 377 PIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSAIILDFRLEEF-Q 435
            IRHD+TT P GDY+RLL PG + + A   G+ +  + V +P   K A  +DF L+    
Sbjct: 516 GIRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFILQPLGM 575

Query: 436 GKTNWLQDLSSFGVYSP 452
           G  N++  L   G + P
Sbjct: 576 GPKNFIHGLRRTGPHDP 592


>BC045549-1|AAH45549.1| 1380|Homo sapiens carboxypeptidase D
           protein.
          Length = 1380

 Score =  325 bits (799), Expect = 2e-88
 Identities = 181/412 (43%), Positives = 252/412 (61%), Gaps = 47/412 (11%)

Query: 23  HHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKYIG 82
           HHN  ++ + L+   N  PNITR+Y+L + SV +  LYV+E +  PG H P  PE KYIG
Sbjct: 503 HHNFPDMEIFLRRFANEYPNITRLYSLGK-SVESRELYVMEISDNPGVHEPGEPEFKYIG 561

Query: 83  NIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDTGGK 142
           N+HGNEV+GRELLL L  YLC  +   DPE+  L+ NTRIHL+PSMNPDG++ + + G  
Sbjct: 562 NMHGNEVVGRELLLNLIEYLCKNFG-TDPEVTDLVHNTRIHLMPSMNPDGYEKSQE-GDS 619

Query: 143 DYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQLSAPLEPETRAVMRW 202
             +IGR N++  DLNRNFPD                        Q++ P +PET AVM W
Sbjct: 620 ISVIGRNNSNNFDLNRNFPD---------------------QFVQITDPTQPETIAVMSW 658

Query: 203 IMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFKELAMTYALAHADMAS 262
           + S PFVLSA +HGG LV NYP+D+ + G   A YS SPDD  F+++A++Y+  ++ M  
Sbjct: 659 MKSYPFVLSANLHGGSLVVNYPFDDDEQGL--ATYSKSPDDAVFQQIALSYSKENSQMFQ 716

Query: 263 PTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLELGCEKYP 322
              R C     ++   +     G+TNGA+WY++ GGMQD+NYL TN FE+T+ELGC KYP
Sbjct: 717 G--RPCKNMYPNEYFPH-----GITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYP 769

Query: 323 SAELLETEWNRNREALVEYLWKAHIGVKGVV---SDSKGFIPNAIISVVNCTGSVTKPIR 379
             + L   W +NR +L++++ + H GV+G V   +D +G + NA ISV          I 
Sbjct: 770 LEKELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATDGRGIL-NATISVAE--------IN 820

Query: 380 HDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSAIILDFRL 431
           H VTT   GDY+RLL PG Y+ITA+  G+   ++ V+V    + AI ++F L
Sbjct: 821 HPVTTYKTGDYWRLLVPGTYKITASARGYNPVTKNVTV--KSEGAIQVNFTL 870



 Score =  252 bits (617), Expect = 2e-66
 Identities = 147/367 (40%), Positives = 203/367 (55%), Gaps = 42/367 (11%)

Query: 73  PYIPEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDG 132
           P  P+ K +GN+HG+E + R++L+ LA  L   YR+ DP +  L+  T ++LLPS+NPDG
Sbjct: 127 PGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDG 186

Query: 133 WQLATD------TGGKDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLT 186
           ++ A +       GG     GR N+   DLNR+FPD          Q  +     L ++ 
Sbjct: 187 FERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPD----------QFSTGEPPALDEV- 235

Query: 187 QLSAPLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETF 246
                  PE RA++ WI    FVLS  +HGG +VA+YP+D+S    +   YS + DDE F
Sbjct: 236 -------PEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATGIYSKTSDDEVF 288

Query: 247 KELAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLA 306
           K LA  YA  H  M +      H    +D ++    + G+TNGA WY ++GGMQD+NY+ 
Sbjct: 289 KYLAKAYASNHPIMKTGEP---HCPGDEDETF----KDGITNGAHWYDVEGGMQDYNYVW 341

Query: 307 TNAFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDS--KGFIPNAI 364
            N FEITLEL C KYP A  L  EW  NRE+L+  + K HIGVKG V DS     + NA 
Sbjct: 342 ANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENAT 401

Query: 365 ISVVNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSA 424
           ISV          I H++TTG +GD+YRLL PG Y +T   TG+   + + +V   +  A
Sbjct: 402 ISVAG--------INHNITTGRFGDFYRLLVPGTYNLTVVLTGYMPLT-VTNVVVKEGPA 452

Query: 425 IILDFRL 431
             +DF L
Sbjct: 453 TGVDFSL 459



 Score =  152 bits (368), Expect = 3e-36
 Identities = 122/410 (29%), Positives = 193/410 (47%), Gaps = 54/410 (13%)

Query: 21   WKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKY 80
            +++H+ ++L   L+ +  N P+IT +  L + +     ++ +E +  P    P  P+ ++
Sbjct: 931  YRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYR-HIWSLEISNKPNVSEPEEPKIRF 989

Query: 81   IGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDTG 140
            +  IHGN  +G ELLL LA +LC  Y+KN P +  L+  TRI ++PS+NPDG + A +  
Sbjct: 990  VAGIHGNAPVGTELLLALAEFLCLNYKKN-PAVTQLVDRTRIVIVPSLNPDGRERAQEKD 1048

Query: 141  GKDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQLSAPLEPETRAVM 200
                 IG+TN    DL+           DF       NN             +PET+A++
Sbjct: 1049 CTSK-IGQTNARGKDLDT----------DFT------NN-----------ASQPETKAII 1080

Query: 201  R-WIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFKELAMTYALAHAD 259
               I    F LS A+ GG ++  YPYD+              + ET K LA  YA  H  
Sbjct: 1081 ENLIQKQDFSLSVALDGGSMLVTYPYDKP--------VQTVENKETLKHLASLYANNHPS 1132

Query: 260  MASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLELGCE 319
            M    +  C   S +++       GGV  GA W+S  G M+D++    +  EIT+   C 
Sbjct: 1133 MHMG-QPSCPNKSDENIP------GGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSCC 1185

Query: 320  KYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGFIPNAIISVVNCTGSVTKPIR 379
             +PSA  L + W  N+ +L+  L + H GV G V D  G   +  + V+N      + I+
Sbjct: 1186 YFPSAARLPSLWADNKRSLLSMLVEVHKGVHGFVKDKTGKPISKAVIVLN------EGIK 1239

Query: 380  HDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSAIILDF 429
                 G Y  ++ LL PG + I A   G+ Q    V V  +  S++++ F
Sbjct: 1240 VQTKEGGY--FHVLLAPGVHNIIAIADGYQQQHSQVFVHHDAASSVVIVF 1287


>U65090-1|AAC51775.2| 1380|Homo sapiens carboxypeptidase D protein.
          Length = 1380

 Score =  323 bits (794), Expect = 7e-88
 Identities = 180/412 (43%), Positives = 252/412 (61%), Gaps = 47/412 (11%)

Query: 23  HHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKYIG 82
           HH+  ++ + L+   N  PNITR+Y+L + SV +  LYV+E +  PG H P  PE KYIG
Sbjct: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGK-SVESRELYVMEISDNPGVHEPGEPEFKYIG 561

Query: 83  NIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDTGGK 142
           N+HGNEV+GRELLL L  YLC  +   DPE+  L+ NTRIHL+PSMNPDG++ + + G  
Sbjct: 562 NMHGNEVVGRELLLNLIEYLCKNFG-TDPEVTDLVHNTRIHLMPSMNPDGYEKSQE-GDS 619

Query: 143 DYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQLSAPLEPETRAVMRW 202
             +IGR N++  DLNRNFPD                        Q++ P +PET AVM W
Sbjct: 620 ISVIGRNNSNNFDLNRNFPD---------------------QFVQITDPTQPETIAVMSW 658

Query: 203 IMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFKELAMTYALAHADMAS 262
           + S PFVLSA +HGG LV NYP+D+ + G   A YS SPDD  F+++A++Y+  ++ M  
Sbjct: 659 MKSYPFVLSANLHGGSLVVNYPFDDDEQGL--ATYSKSPDDAVFQQIALSYSKENSQMFQ 716

Query: 263 PTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLELGCEKYP 322
              R C     ++   +     G+TNGA+WY++ GGMQD+NYL TN FE+T+ELGC KYP
Sbjct: 717 G--RPCKNMYPNEYFPH-----GITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYP 769

Query: 323 SAELLETEWNRNREALVEYLWKAHIGVKGVV---SDSKGFIPNAIISVVNCTGSVTKPIR 379
             + L   W +NR +L++++ + H GV+G V   +D +G + NA ISV          I 
Sbjct: 770 LEKELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATDGRGIL-NATISVAE--------IN 820

Query: 380 HDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSAIILDFRL 431
           H VTT   GDY+RLL PG Y+ITA+  G+   ++ V+V    + AI ++F L
Sbjct: 821 HPVTTYKTGDYWRLLVPGTYKITASARGYNPVTKNVTV--KSEGAIQVNFTL 870



 Score =  252 bits (618), Expect = 2e-66
 Identities = 147/367 (40%), Positives = 203/367 (55%), Gaps = 42/367 (11%)

Query: 73  PYIPEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDG 132
           P  P+ K +GN+HG+E + R++L+ LA  L   YR+ DP +  L+  T ++LLPS+NPDG
Sbjct: 127 PGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDG 186

Query: 133 WQLATD------TGGKDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLT 186
           ++ A +       GG     GR N+   DLNR+FPD          Q  +     L ++ 
Sbjct: 187 FERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPD----------QFSTGEPPALDEV- 235

Query: 187 QLSAPLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETF 246
                  PE RA++ WI    FVLS  +HGG +VA+YP+D+S    +   YS + DDE F
Sbjct: 236 -------PEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATGIYSKTSDDEVF 288

Query: 247 KELAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLA 306
           K LA  YA  H  M +      H    +D ++    + G+TNGA WY ++GGMQD+NY+ 
Sbjct: 289 KYLAKAYASNHPIMKTGEP---HCPGDEDETF----KDGITNGAHWYDVEGGMQDYNYVW 341

Query: 307 TNAFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDS--KGFIPNAI 364
            N FEITLEL C KYP A  L  EW  NRE+L+  + K HIGVKG V DS     + NA 
Sbjct: 342 ANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENAT 401

Query: 365 ISVVNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSA 424
           ISV          I H++TTG +GD+YRLL PG Y +T   TG+   + + +V   +  A
Sbjct: 402 ISVAG--------INHNITTGRFGDFYRLLVPGTYNLTVVLTGYMPLT-VTNVVVKEGPA 452

Query: 425 IILDFRL 431
             +DF L
Sbjct: 453 TEVDFSL 459



 Score =  151 bits (367), Expect = 4e-36
 Identities = 122/410 (29%), Positives = 193/410 (47%), Gaps = 54/410 (13%)

Query: 21   WKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKY 80
            +++H+ ++L   L+ +  N P+IT +  L + +     ++ +E +  P    P  P+ ++
Sbjct: 931  YRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYR-HIWSLEISNKPNVSEPEEPKIRF 989

Query: 81   IGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDTG 140
            +  IHGN  +G ELLL LA +LC  Y+KN P +  L+  TRI ++PS+NPDG + A +  
Sbjct: 990  VAGIHGNAPVGTELLLALAEFLCLNYKKN-PAVTQLVDRTRIVIVPSLNPDGRERAQEKD 1048

Query: 141  GKDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQLSAPLEPETRAVM 200
                 IG+TN    DL+           DF       NN             +PET+A++
Sbjct: 1049 CTSK-IGQTNARGKDLDT----------DFT------NN-----------ASQPETKAII 1080

Query: 201  R-WIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFKELAMTYALAHAD 259
               I    F LS A+ GG ++  YPYD+              + ET K LA  YA  H  
Sbjct: 1081 ENLIQKQNFSLSVALDGGSMLVTYPYDKP--------VQTVENKETLKHLASLYANNHPS 1132

Query: 260  MASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLELGCE 319
            M    +  C   S +++       GGV  GA W+S  G M+D++    +  EIT+   C 
Sbjct: 1133 MHMG-QPSCPNKSDENIP------GGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSCC 1185

Query: 320  KYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGFIPNAIISVVNCTGSVTKPIR 379
             +PSA  L + W  N+ +L+  L + H GV G V D  G   +  + V+N      + I+
Sbjct: 1186 YFPSAARLPSLWADNKRSLLSMLVEVHKGVHGFVKDKTGKPISKAVIVLN------EGIK 1239

Query: 380  HDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSAIILDF 429
                 G Y  ++ LL PG + I A   G+ Q    V V  +  S++++ F
Sbjct: 1240 VQTKEGGY--FHVLLAPGVHNIIAIADGYQQQHSQVFVHHDAASSVVIVF 1287


>D85390-1|BAA33370.1| 1380|Homo sapiens gp180-carboxypeptidase
           D-like enzyme protein.
          Length = 1380

 Score =  323 bits (794), Expect = 7e-88
 Identities = 180/412 (43%), Positives = 252/412 (61%), Gaps = 47/412 (11%)

Query: 23  HHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKYIG 82
           HH+  ++ + L+   N  PNITR+Y+L + SV +  LYV+E +  PG H P  PE KYIG
Sbjct: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGK-SVESRELYVMEISDNPGVHEPGEPEFKYIG 561

Query: 83  NIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDTGGK 142
           N+HGNEV+GRELLL L  YLC  +   DPE+  L+ NTRIHL+PSMNPDG++ + + G  
Sbjct: 562 NMHGNEVVGRELLLNLIEYLCKNFG-TDPEVTDLVHNTRIHLMPSMNPDGYEKSQE-GDS 619

Query: 143 DYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQLSAPLEPETRAVMRW 202
             +IGR N++  DLNRNFPD                        Q++ P +PET AVM W
Sbjct: 620 ISVIGRNNSNNFDLNRNFPD---------------------QFVQITDPTQPETIAVMSW 658

Query: 203 IMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFKELAMTYALAHADMAS 262
           + S PFVLSA +HGG LV NYP+D+ + G   A YS SPDD  F+++A++Y+  ++ M  
Sbjct: 659 MKSYPFVLSANLHGGSLVVNYPFDDDEQGL--ATYSKSPDDAVFQQIALSYSKENSQMFQ 716

Query: 263 PTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLELGCEKYP 322
              R C     ++   +     G+TNGA+WY++ GGMQD+NYL TN FE+T+ELGC KYP
Sbjct: 717 G--RPCKNMYPNEYFPH-----GITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYP 769

Query: 323 SAELLETEWNRNREALVEYLWKAHIGVKGVV---SDSKGFIPNAIISVVNCTGSVTKPIR 379
             + L   W +NR +L++++ + H GV+G V   +D +G + NA ISV          I 
Sbjct: 770 LEKELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATDGRGIL-NATISVAE--------IN 820

Query: 380 HDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSAIILDFRL 431
           H VTT   GDY+RLL PG Y+ITA+  G+   ++ V+V    + AI ++F L
Sbjct: 821 HPVTTYKTGDYWRLLVPGTYKITASARGYNPVTKNVTV--KSEGAIQVNFTL 870



 Score =  252 bits (618), Expect = 2e-66
 Identities = 147/367 (40%), Positives = 203/367 (55%), Gaps = 42/367 (11%)

Query: 73  PYIPEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDG 132
           P  P+ K +GN+HG+E + R++L+ LA  L   YR+ DP +  L+  T ++LLPS+NPDG
Sbjct: 127 PGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDG 186

Query: 133 WQLATD------TGGKDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLT 186
           ++ A +       GG     GR N+   DLNR+FPD          Q  +     L ++ 
Sbjct: 187 FERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPD----------QFSTGEPPALDEV- 235

Query: 187 QLSAPLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETF 246
                  PE RA++ WI    FVLS  +HGG +VA+YP+D+S    +   YS + DDE F
Sbjct: 236 -------PEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATGIYSKTSDDEVF 288

Query: 247 KELAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLA 306
           K LA  YA  H  M +      H    +D ++    + G+TNGA WY ++GGMQD+NY+ 
Sbjct: 289 KYLAKAYASNHPIMKTGEP---HCPGDEDETF----KDGITNGAHWYDVEGGMQDYNYVW 341

Query: 307 TNAFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDS--KGFIPNAI 364
            N FEITLEL C KYP A  L  EW  NRE+L+  + K HIGVKG V DS     + NA 
Sbjct: 342 ANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENAT 401

Query: 365 ISVVNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSA 424
           ISV          I H++TTG +GD+YRLL PG Y +T   TG+   + + +V   +  A
Sbjct: 402 ISVAG--------INHNITTGRFGDFYRLLVPGTYNLTVVLTGYMPLT-VTNVVVKEGPA 452

Query: 425 IILDFRL 431
             +DF L
Sbjct: 453 TEVDFSL 459



 Score =  152 bits (368), Expect = 3e-36
 Identities = 122/410 (29%), Positives = 193/410 (47%), Gaps = 54/410 (13%)

Query: 21   WKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKY 80
            +++H+ ++L   L+ +  N P+IT +  L + +     ++ +E +  P    P  P+ ++
Sbjct: 931  YRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYR-HIWSLEISNKPNVSEPEEPKIRF 989

Query: 81   IGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDTG 140
            +  IHGN  +G ELLL LA +LC  Y+KN P +  L+  TRI ++PS+NPDG + A +  
Sbjct: 990  VAGIHGNAPVGTELLLALAEFLCLNYKKN-PAVTQLVDRTRIVIVPSLNPDGRERAQEKD 1048

Query: 141  GKDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQLSAPLEPETRAVM 200
                 IG+TN    DL+           DF       NN             +PET+A++
Sbjct: 1049 CTSK-IGQTNARGKDLDT----------DFT------NN-----------ASQPETKAII 1080

Query: 201  R-WIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFKELAMTYALAHAD 259
               I    F LS A+ GG ++  YPYD+              + ET K LA  YA  H  
Sbjct: 1081 ENLIQKQDFSLSVALDGGSMLVTYPYDKP--------VQTVENKETLKHLASLYANNHPS 1132

Query: 260  MASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLELGCE 319
            M    +  C   S +++       GGV  GA W+S  G M+D++    +  EIT+   C 
Sbjct: 1133 MHMG-QPSCPNKSDENIP------GGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSCC 1185

Query: 320  KYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGFIPNAIISVVNCTGSVTKPIR 379
             +PSA  L + W  N+ +L+  L + H GV G V D  G   +  + V+N      + I+
Sbjct: 1186 YFPSAARLPSLWADNKRSLLSMLVEVHKGVHGFVKDKTGKPISKAVIVLN------EGIK 1239

Query: 380  HDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSAIILDF 429
                 G Y  ++ LL PG + I A   G+ Q    V V  +  S++++ F
Sbjct: 1240 VQTKEGGY--FHVLLAPGVHNIIAIADGYQQQHSQVFVHHDAASSVVIVF 1287


>BC063430-1|AAH63430.1|  734|Homo sapiens carboxypeptidase X (M14
           family), member 1 protein.
          Length = 734

 Score =  323 bits (794), Expect = 7e-88
 Identities = 168/408 (41%), Positives = 250/408 (61%), Gaps = 26/408 (6%)

Query: 16  SAEFQWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYI 75
           S    ++HHN + +  ++++V   CPNITRIY++ + S   + LYV+E +  PG H    
Sbjct: 292 SDPLDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGK-SYQGLKLYVMEMSDKPGEHELGE 350

Query: 76  PEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQL 135
           PE +Y+  +HGNE LGRELLL L  +LC ++ + +P +  L++  RIHLLPSMNPDG+++
Sbjct: 351 PEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEI 410

Query: 136 ATDTGGK--DYLIGRTNNHEVDLNRNFPDLDAITFDFERQG-LSH---NNHLLKD--LTQ 187
           A   G +   +  GR NN  +DLN NF DL+   ++ +  G + H   N+HL      T 
Sbjct: 411 AYHRGSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTL 470

Query: 188 LSAPLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFK 247
            +A + PETRAV++W+   PFVLSA +HGG+LV +YP+D ++T  +A E + +PDD  F+
Sbjct: 471 PNATVAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFR 530

Query: 248 ELAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLAT 307
            L+  YA ++  M   +RR CH       S +F   G + NGA W+++ G M DF+YL T
Sbjct: 531 WLSTVYAGSNLAMQDTSRRPCH-------SQDFSVHGNIINGADWHTVPGSMNDFSYLHT 583

Query: 308 NAFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVV--SDSKGFIPNAII 365
           N FE+T+EL C+K+P    L  EW  N++AL+ YL +  +G+ GVV   D++  I +A+I
Sbjct: 584 NCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVI 643

Query: 366 SVVNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASR 413
           +V          I HDVTT   GDY+RLLTPG Y +TA+  G+   +R
Sbjct: 644 AV--------DGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVTR 683


>BC051702-1|AAH51702.1| 1380|Homo sapiens carboxypeptidase D
           protein.
          Length = 1380

 Score =  323 bits (794), Expect = 7e-88
 Identities = 180/412 (43%), Positives = 252/412 (61%), Gaps = 47/412 (11%)

Query: 23  HHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKYIG 82
           HH+  ++ + L+   N  PNITR+Y+L + SV +  LYV+E +  PG H P  PE KYIG
Sbjct: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGK-SVESRELYVMEISDNPGVHEPGEPEFKYIG 561

Query: 83  NIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDTGGK 142
           N+HGNEV+GRELLL L  YLC  +   DPE+  L+ NTRIHL+PSMNPDG++ + + G  
Sbjct: 562 NMHGNEVVGRELLLNLIEYLCKNFG-TDPEVTDLVHNTRIHLMPSMNPDGYEKSQE-GDS 619

Query: 143 DYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQLSAPLEPETRAVMRW 202
             +IGR N++  DLNRNFPD                        Q++ P +PET AVM W
Sbjct: 620 ISVIGRNNSNNFDLNRNFPD---------------------QFVQITDPTQPETIAVMSW 658

Query: 203 IMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFKELAMTYALAHADMAS 262
           + S PFVLSA +HGG LV NYP+D+ + G   A YS SPDD  F+++A++Y+  ++ M  
Sbjct: 659 MKSYPFVLSANLHGGSLVVNYPFDDDEQGL--ATYSKSPDDAVFQQIALSYSKENSQMFQ 716

Query: 263 PTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLELGCEKYP 322
              R C     ++   +     G+TNGA+WY++ GGMQD+NYL TN FE+T+ELGC KYP
Sbjct: 717 G--RPCKNMYPNEYFPH-----GITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYP 769

Query: 323 SAELLETEWNRNREALVEYLWKAHIGVKGVV---SDSKGFIPNAIISVVNCTGSVTKPIR 379
             + L   W +NR +L++++ + H GV+G V   +D +G + NA ISV          I 
Sbjct: 770 LEKELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATDGRGIL-NATISVAE--------IN 820

Query: 380 HDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSAIILDFRL 431
           H VTT   GDY+RLL PG Y+ITA+  G+   ++ V+V    + AI ++F L
Sbjct: 821 HPVTTYKTGDYWRLLVPGTYKITASARGYNPVTKNVTV--KSEGAIQVNFTL 870



 Score =  252 bits (618), Expect = 2e-66
 Identities = 147/367 (40%), Positives = 203/367 (55%), Gaps = 42/367 (11%)

Query: 73  PYIPEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDG 132
           P  P+ K +GN+HG+E + R++L+ LA  L   YR+ DP +  L+  T ++LLPS+NPDG
Sbjct: 127 PGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDG 186

Query: 133 WQLATD------TGGKDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLT 186
           ++ A +       GG     GR N+   DLNR+FPD          Q  +     L ++ 
Sbjct: 187 FERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPD----------QFSTGEPPALDEV- 235

Query: 187 QLSAPLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETF 246
                  PE RA++ WI    FVLS  +HGG +VA+YP+D+S    +   YS + DDE F
Sbjct: 236 -------PEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATGIYSKTSDDEVF 288

Query: 247 KELAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLA 306
           K LA  YA  H  M +      H    +D ++    + G+TNGA WY ++GGMQD+NY+ 
Sbjct: 289 KYLAKAYASNHPIMKTGEP---HCPGDEDETF----KDGITNGAHWYDVEGGMQDYNYVW 341

Query: 307 TNAFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDS--KGFIPNAI 364
            N FEITLEL C KYP A  L  EW  NRE+L+  + K HIGVKG V DS     + NA 
Sbjct: 342 ANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENAT 401

Query: 365 ISVVNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSA 424
           ISV          I H++TTG +GD+YRLL PG Y +T   TG+   + + +V   +  A
Sbjct: 402 ISVAG--------INHNITTGRFGDFYRLLVPGTYNLTVVLTGYMPLT-VTNVVVKEGPA 452

Query: 425 IILDFRL 431
             +DF L
Sbjct: 453 TEVDFSL 459



 Score =  152 bits (368), Expect = 3e-36
 Identities = 122/410 (29%), Positives = 193/410 (47%), Gaps = 54/410 (13%)

Query: 21   WKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKY 80
            +++H+ ++L   L+ +  N P+IT +  L + +     ++ +E +  P    P  P+ ++
Sbjct: 931  YRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYR-HIWSLEISNKPNVSEPEEPKIRF 989

Query: 81   IGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDTG 140
            +  IHGN  +G ELLL LA +LC  Y+KN P +  L+  TRI ++PS+NPDG + A +  
Sbjct: 990  VAGIHGNAPVGTELLLALAEFLCLNYKKN-PAVTQLVDRTRIVIVPSLNPDGRERAQEKD 1048

Query: 141  GKDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQLSAPLEPETRAVM 200
                 IG+TN    DL+           DF       NN             +PET+A++
Sbjct: 1049 CTSK-IGQTNARGKDLDT----------DFT------NN-----------ASQPETKAII 1080

Query: 201  R-WIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFKELAMTYALAHAD 259
               I    F LS A+ GG ++  YPYD+              + ET K LA  YA  H  
Sbjct: 1081 ENLIQKQDFSLSVALDGGSMLVTYPYDKP--------VQTVENKETLKHLASLYANNHPS 1132

Query: 260  MASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLELGCE 319
            M    +  C   S +++       GGV  GA W+S  G M+D++    +  EIT+   C 
Sbjct: 1133 MHMG-QPSCPNKSDENIP------GGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSCC 1185

Query: 320  KYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGFIPNAIISVVNCTGSVTKPIR 379
             +PSA  L + W  N+ +L+  L + H GV G V D  G   +  + V+N      + I+
Sbjct: 1186 YFPSAARLPSLWADNKRSLLSMLVEVHKGVHGFVKDKTGKPISKAVIVLN------EGIK 1239

Query: 380  HDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSAIILDF 429
                 G Y  ++ LL PG + I A   G+ Q    V V  +  S++++ F
Sbjct: 1240 VQTKEGGY--FHVLLAPGVHNIIAIADGYQQQHSQVFVHHDAASSVVIVF 1287


>BC045624-1|AAH45624.1| 1380|Homo sapiens carboxypeptidase D
           protein.
          Length = 1380

 Score =  323 bits (794), Expect = 7e-88
 Identities = 180/412 (43%), Positives = 252/412 (61%), Gaps = 47/412 (11%)

Query: 23  HHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKYIG 82
           HH+  ++ + L+   N  PNITR+Y+L + SV +  LYV+E +  PG H P  PE KYIG
Sbjct: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGK-SVESRELYVMEISDNPGVHEPGEPEFKYIG 561

Query: 83  NIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDTGGK 142
           N+HGNEV+GRELLL L  YLC  +   DPE+  L+ NTRIHL+PSMNPDG++ + + G  
Sbjct: 562 NMHGNEVVGRELLLNLIEYLCKNFG-TDPEVTDLVHNTRIHLMPSMNPDGYEKSQE-GDS 619

Query: 143 DYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQLSAPLEPETRAVMRW 202
             +IGR N++  DLNRNFPD                        Q++ P +PET AVM W
Sbjct: 620 ISVIGRNNSNNFDLNRNFPD---------------------QFVQITDPTQPETIAVMSW 658

Query: 203 IMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFKELAMTYALAHADMAS 262
           + S PFVLSA +HGG LV NYP+D+ + G   A YS SPDD  F+++A++Y+  ++ M  
Sbjct: 659 MKSYPFVLSANLHGGSLVVNYPFDDDEQGL--ATYSKSPDDAVFQQIALSYSKENSQMFQ 716

Query: 263 PTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLELGCEKYP 322
              R C     ++   +     G+TNGA+WY++ GGMQD+NYL TN FE+T+ELGC KYP
Sbjct: 717 G--RPCKNMYPNEYFPH-----GITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYP 769

Query: 323 SAELLETEWNRNREALVEYLWKAHIGVKGVV---SDSKGFIPNAIISVVNCTGSVTKPIR 379
             + L   W +NR +L++++ + H GV+G V   +D +G + NA ISV          I 
Sbjct: 770 LEKELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATDGRGIL-NATISVAE--------IN 820

Query: 380 HDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSAIILDFRL 431
           H VTT   GDY+RLL PG Y+ITA+  G+   ++ V+V    + AI ++F L
Sbjct: 821 HPVTTYKTGDYWRLLVPGTYKITASARGYNPVTKNVTV--KSEGAIQVNFTL 870



 Score =  252 bits (618), Expect = 2e-66
 Identities = 147/367 (40%), Positives = 203/367 (55%), Gaps = 42/367 (11%)

Query: 73  PYIPEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDG 132
           P  P+ K +GN+HG+E + R++L+ LA  L   YR+ DP +  L+  T ++LLPS+NPDG
Sbjct: 127 PGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDG 186

Query: 133 WQLATD------TGGKDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLT 186
           ++ A +       GG     GR N+   DLNR+FPD          Q  +     L ++ 
Sbjct: 187 FERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPD----------QFSTGEPPALDEV- 235

Query: 187 QLSAPLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETF 246
                  PE RA++ WI    FVLS  +HGG +VA+YP+D+S    +   YS + DDE F
Sbjct: 236 -------PEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATGIYSKTSDDEVF 288

Query: 247 KELAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLA 306
           K LA  YA  H  M +      H    +D ++    + G+TNGA WY ++GGMQD+NY+ 
Sbjct: 289 KYLAKAYASNHPIMKTGEP---HCPGDEDETF----KDGITNGAHWYDVEGGMQDYNYVW 341

Query: 307 TNAFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDS--KGFIPNAI 364
            N FEITLEL C KYP A  L  EW  NRE+L+  + K HIGVKG V DS     + NA 
Sbjct: 342 ANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENAT 401

Query: 365 ISVVNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSA 424
           ISV          I H++TTG +GD+YRLL PG Y +T   TG+   + + +V   +  A
Sbjct: 402 ISVAG--------INHNITTGRFGDFYRLLVPGTYNLTVVLTGYMPLT-VTNVVVKEGPA 452

Query: 425 IILDFRL 431
             +DF L
Sbjct: 453 TEVDFSL 459



 Score =  152 bits (368), Expect = 3e-36
 Identities = 122/410 (29%), Positives = 193/410 (47%), Gaps = 54/410 (13%)

Query: 21   WKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKY 80
            +++H+ ++L   L+ +  N P+IT +  L + +     ++ +E +  P    P  P+ ++
Sbjct: 931  YRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYR-HIWSLEISNKPNVSEPEEPKIRF 989

Query: 81   IGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDTG 140
            +  IHGN  +G ELLL LA +LC  Y+KN P +  L+  TRI ++PS+NPDG + A +  
Sbjct: 990  VAGIHGNAPVGTELLLALAEFLCLNYKKN-PAVTQLVDRTRIVIVPSLNPDGRERAQEKD 1048

Query: 141  GKDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQLSAPLEPETRAVM 200
                 IG+TN    DL+           DF       NN             +PET+A++
Sbjct: 1049 CTSK-IGQTNARGKDLDT----------DFT------NN-----------ASQPETKAII 1080

Query: 201  R-WIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFKELAMTYALAHAD 259
               I    F LS A+ GG ++  YPYD+              + ET K LA  YA  H  
Sbjct: 1081 ENLIQKQDFSLSVALDGGSMLVTYPYDKP--------VQTVENKETLKHLASLYANNHPS 1132

Query: 260  MASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLELGCE 319
            M    +  C   S +++       GGV  GA W+S  G M+D++    +  EIT+   C 
Sbjct: 1133 MHMG-QPSCPNKSDENIP------GGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSCC 1185

Query: 320  KYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGFIPNAIISVVNCTGSVTKPIR 379
             +PSA  L + W  N+ +L+  L + H GV G V D  G   +  + V+N      + I+
Sbjct: 1186 YFPSAARLPSLWADNKRSLLSMLVEVHKGVHGFVKDKTGKPISKAVIVLN------EGIK 1239

Query: 380  HDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKSAIILDF 429
                 G Y  ++ LL PG + I A   G+ Q    V V  +  S++++ F
Sbjct: 1240 VQTKEGGY--FHVLLAPGVHNIIAIADGYQQQHSQVFVHHDAASSVVIVF 1287


>AY358956-1|AAQ89315.1|  734|Homo sapiens CPXM protein.
          Length = 734

 Score =  323 bits (794), Expect = 7e-88
 Identities = 168/408 (41%), Positives = 250/408 (61%), Gaps = 26/408 (6%)

Query: 16  SAEFQWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYI 75
           S    ++HHN + +  ++++V   CPNITRIY++ + S   + LYV+E +  PG H    
Sbjct: 292 SDPLDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGK-SYQGLKLYVMEMSDKPGEHELGE 350

Query: 76  PEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQL 135
           PE +Y+  +HGNE LGRELLL L  +LC ++ + +P +  L++  RIHLLPSMNPDG+++
Sbjct: 351 PEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEI 410

Query: 136 ATDTGGK--DYLIGRTNNHEVDLNRNFPDLDAITFDFERQG-LSH---NNHLLKD--LTQ 187
           A   G +   +  GR NN  +DLN NF DL+   ++ +  G + H   N+HL      T 
Sbjct: 411 AYHRGSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTL 470

Query: 188 LSAPLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFK 247
            +A + PETRAV++W+   PFVLSA +HGG+LV +YP+D ++T  +A E + +PDD  F+
Sbjct: 471 PNATVAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFR 530

Query: 248 ELAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLAT 307
            L+  YA ++  M   +RR CH       S +F   G + NGA W+++ G M DF+YL T
Sbjct: 531 WLSTVYAGSNLAMQDTSRRPCH-------SQDFSVHGNIINGADWHTVPGSMNDFSYLHT 583

Query: 308 NAFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVV--SDSKGFIPNAII 365
           N FE+T+EL C+K+P    L  EW  N++AL+ YL +  +G+ GVV   D++  I +A+I
Sbjct: 584 NCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVI 643

Query: 366 SVVNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASR 413
           +V          I HDVTT   GDY+RLLTPG Y +TA+  G+   +R
Sbjct: 644 AV--------DGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVTR 683


>AL035460-3|CAB82246.1|  734|Homo sapiens carboxypeptidase X (M14
           family), member 1 protein.
          Length = 734

 Score =  323 bits (794), Expect = 7e-88
 Identities = 168/408 (41%), Positives = 250/408 (61%), Gaps = 26/408 (6%)

Query: 16  SAEFQWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYI 75
           S    ++HHN + +  ++++V   CPNITRIY++ + S   + LYV+E +  PG H    
Sbjct: 292 SDPLDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGK-SYQGLKLYVMEMSDKPGEHELGE 350

Query: 76  PEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQL 135
           PE +Y+  +HGNE LGRELLL L  +LC ++ + +P +  L++  RIHLLPSMNPDG+++
Sbjct: 351 PEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEI 410

Query: 136 ATDTGGK--DYLIGRTNNHEVDLNRNFPDLDAITFDFERQG-LSH---NNHLLKD--LTQ 187
           A   G +   +  GR NN  +DLN NF DL+   ++ +  G + H   N+HL      T 
Sbjct: 411 AYHRGSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTL 470

Query: 188 LSAPLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFK 247
            +A + PETRAV++W+   PFVLSA +HGG+LV +YP+D ++T  +A E + +PDD  F+
Sbjct: 471 PNATVAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFR 530

Query: 248 ELAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLAT 307
            L+  YA ++  M   +RR CH       S +F   G + NGA W+++ G M DF+YL T
Sbjct: 531 WLSTVYAGSNLAMQDTSRRPCH-------SQDFSVHGNIINGADWHTVPGSMNDFSYLHT 583

Query: 308 NAFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVV--SDSKGFIPNAII 365
           N FE+T+EL C+K+P    L  EW  N++AL+ YL +  +G+ GVV   D++  I +A+I
Sbjct: 584 NCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVI 643

Query: 366 SVVNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASR 413
           +V          I HDVTT   GDY+RLLTPG Y +TA+  G+   +R
Sbjct: 644 AV--------DGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVTR 683


>AK027661-1|BAB55275.1|  734|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14755 fis, clone NT2RP3003145, moderately
           similar to Mus musculus metallocarboxypeptidase CPX-1
           mRNA. ).
          Length = 734

 Score =  322 bits (792), Expect = 1e-87
 Identities = 168/408 (41%), Positives = 250/408 (61%), Gaps = 26/408 (6%)

Query: 16  SAEFQWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYI 75
           S    ++HHN + +  ++++V   CPNITRIY++ + S   + LYV+E +  PG H    
Sbjct: 292 SDPLDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGK-SYQGLKLYVMEMSDKPGEHELGE 350

Query: 76  PEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQL 135
           PE +Y+  +HGNE LGRELLL L  +LC ++ + +P +  L++  RIHLLPSMNPDG+++
Sbjct: 351 PEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTWLLSEMRIHLLPSMNPDGYEI 410

Query: 136 ATDTGGK--DYLIGRTNNHEVDLNRNFPDLDAITFDFERQG-LSH---NNHLLKD--LTQ 187
           A   G +   +  GR NN  +DLN NF DL+   ++ +  G + H   N+HL      T 
Sbjct: 411 AYHRGSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTL 470

Query: 188 LSAPLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFK 247
            +A + PETRAV++W+   PFVLSA +HGG+LV +YP+D ++T  +A E + +PDD  F+
Sbjct: 471 PNATVAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFR 530

Query: 248 ELAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLAT 307
            L+  YA ++  M   +RR CH       S +F   G + NGA W+++ G M DF+YL T
Sbjct: 531 WLSTVYAGSNLAMQDTSRRPCH-------SQDFSVHGNIINGADWHTVPGSMNDFSYLHT 583

Query: 308 NAFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVV--SDSKGFIPNAII 365
           N FE+T+EL C+K+P    L  EW  N++AL+ YL +  +G+ GVV   D++  I +A+I
Sbjct: 584 NCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVI 643

Query: 366 SVVNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASR 413
           +V          I HDVTT   GDY+RLLTPG Y +TA+  G+   +R
Sbjct: 644 AV--------DGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVTR 683


>BC036789-1|AAH36789.2|  756|Homo sapiens carboxypeptidase X (M14
           family), member 2 protein.
          Length = 756

 Score =  318 bits (781), Expect = 3e-86
 Identities = 172/430 (40%), Positives = 250/430 (58%), Gaps = 26/430 (6%)

Query: 13  LTVSAEFQWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHR 72
           +T + +  +KHHN +E+  +++ V+  CPNITRIY + + S   + LY +E +  PG H 
Sbjct: 308 MTTTDDLDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGK-SHQGLKLYAVEISDHPGEHE 366

Query: 73  PYIPEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDG 132
              PE  YI   HGNEVLGRELLL L  ++C +Y   +  I  L+  TRIH+LPS+NPDG
Sbjct: 367 VGEPEFHYIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDG 426

Query: 133 WQLATDTGGK--DYLIGRTNNHEVDLNRNFPDLDAITFDFE-RQGLSHN--NHLL---KD 184
           ++ A + G +   + +GR  +  +D+N NFPDL+ + ++ E RQ +     NH +   + 
Sbjct: 427 YEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAIPEW 486

Query: 185 LTQLSAPLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDE 244
               +A +  ETRAV+ W+   PFVL   + GG+LV  YPYD  ++     E++ +PDD 
Sbjct: 487 FLSENATVAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHTPTPDDH 546

Query: 245 TFKELAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNY 304
            F+ LA +YA  H  M    RR CHT        +F K+ G  NGA+W+++ G + DF+Y
Sbjct: 547 VFRWLAYSYASTHRLMTDARRRVCHTE-------DFQKEEGTVNGASWHTVAGSLNDFSY 599

Query: 305 LATNAFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKG-FIPNA 363
           L TN FE+++ +GC+KYP    L  EW  NRE+L+ ++ + H G+KG+V DS G  IPNA
Sbjct: 600 LHTNCFELSIYVGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNA 659

Query: 364 IISVVNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKS 423
           IISV        + I HD+ T   GDY+RLL PG+Y +TA   G F AS    +      
Sbjct: 660 IISV--------EGINHDIRTANDGDYWRLLNPGEYVVTAKAEG-FTASTKNCMVGYDMG 710

Query: 424 AIILDFRLEE 433
           A   DF L +
Sbjct: 711 ATRCDFTLSK 720


>AY358565-1|AAQ88928.1|  756|Homo sapiens carboxypeptidase Hlo
           protein.
          Length = 756

 Score =  318 bits (781), Expect = 3e-86
 Identities = 172/430 (40%), Positives = 250/430 (58%), Gaps = 26/430 (6%)

Query: 13  LTVSAEFQWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHR 72
           +T + +  +KHHN +E+  +++ V+  CPNITRIY + + S   + LY +E +  PG H 
Sbjct: 308 MTTTDDLDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGK-SHQGLKLYAVEISDHPGEHE 366

Query: 73  PYIPEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDG 132
              PE  YI   HGNEVLGRELLL L  ++C +Y   +  I  L+  TRIH+LPS+NPDG
Sbjct: 367 VGEPEFHYIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDG 426

Query: 133 WQLATDTGGK--DYLIGRTNNHEVDLNRNFPDLDAITFDFE-RQGLSHN--NHLL---KD 184
           ++ A + G +   + +GR  +  +D+N NFPDL+ + ++ E RQ +     NH +   + 
Sbjct: 427 YEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAIPEW 486

Query: 185 LTQLSAPLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDE 244
               +A +  ETRAV+ W+   PFVL   + GG+LV  YPYD  ++     E++ +PDD 
Sbjct: 487 FLSENATVAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHTPTPDDH 546

Query: 245 TFKELAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNY 304
            F+ LA +YA  H  M    RR CHT        +F K+ G  NGA+W+++ G + DF+Y
Sbjct: 547 VFRWLAYSYASTHRLMTDARRRVCHTE-------DFQKEEGTVNGASWHTVAGSLNDFSY 599

Query: 305 LATNAFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKG-FIPNA 363
           L TN FE+++ +GC+KYP    L  EW  NRE+L+ ++ + H G+KG+V DS G  IPNA
Sbjct: 600 LHTNCFELSIYVGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNA 659

Query: 364 IISVVNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKNQKS 423
           IISV        + I HD+ T   GDY+RLL PG+Y +TA   G F AS    +      
Sbjct: 660 IISV--------EGINHDIRTANDGDYWRLLNPGEYVVTAKAEG-FTASTKNCMVGYDMG 710

Query: 424 AIILDFRLEE 433
           A   DF L +
Sbjct: 711 ATRCDFTLSK 720


>AK075508-1|BAC11661.1|  430|Homo sapiens protein ( Homo sapiens
           cDNA PSEC0206 fis, clone HEMBA1002913, weakly similar to
           CARBOXYPEPTIDASE H PRECURSOR (EC 3.4.17.10). ).
          Length = 430

 Score =  315 bits (773), Expect = 3e-85
 Identities = 164/392 (41%), Positives = 242/392 (61%), Gaps = 26/392 (6%)

Query: 32  VLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKYIGNIHGNEVLG 91
           ++++V   CPNITRIY++ + S   + LYV+E +  PG H    PE +Y+  +HGNE LG
Sbjct: 4   LMKQVQEQCPNITRIYSIGK-SYQGLKLYVMEMSDKPGEHELGEPEVRYVAGMHGNEALG 62

Query: 92  RELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDTGGK--DYLIGRT 149
           RELLL L  +LC ++ + +P +  L++  RIHLLPSMNPDG+++A   G +   +  GR 
Sbjct: 63  RELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHRGSELVGWAEGRW 122

Query: 150 NNHEVDLNRNFPDLDAITFDFERQG-LSH---NNHLLKD--LTQLSAPLEPETRAVMRWI 203
           NN  +DLN NF DL+   ++ +  G + H   N+HL      T  +A + PETRAV++W+
Sbjct: 123 NNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPNATVAPETRAVIKWM 182

Query: 204 MSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFKELAMTYALAHADMASP 263
              PFVLSA +HGG+LV +YP+D ++T  +A E + +PDD  F+ L+  YA ++  M   
Sbjct: 183 KRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLSTVYAGSNLAMQDT 242

Query: 264 TRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLELGCEKYPS 323
           +RR CH       S +F   G + NGA W+++ G M DF+YL TN FE+T+EL C+K+P 
Sbjct: 243 SRRPCH-------SQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPH 295

Query: 324 AELLETEWNRNREALVEYLWKAHIGVKGVV--SDSKGFIPNAIISVVNCTGSVTKPIRHD 381
              L  EW  N++AL+ YL +  +G+ GVV   D++  I +A+I+V          I HD
Sbjct: 296 ENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAV--------DGINHD 347

Query: 382 VTTGPYGDYYRLLTPGQYEITATHTGHFQASR 413
           VTT   GDY+RLLTPG Y +TA+  G+   +R
Sbjct: 348 VTTAWGGDYWRLLTPGDYMVTASAEGYHSVTR 379


>J04970-1|AAA35651.2|  443|Homo sapiens carboxypeptidase M precursor
           protein.
          Length = 443

 Score =  280 bits (687), Expect = 7e-75
 Identities = 178/431 (41%), Positives = 240/431 (55%), Gaps = 45/431 (10%)

Query: 11  LLLTVSAEFQWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGF 70
           LLL + A   + +H  E +   L+ V  N  ++T ++++ + SV    L+V+   + P  
Sbjct: 10  LLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGK-SVKGRNLWVLVVGRFPKE 68

Query: 71  HRPYIPEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNP 130
           HR  IPE KY+ N+HG+E +GRELLL L  YL     K DPEI  LI +TRIH++PSMNP
Sbjct: 69  HRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGK-DPEITNLINSTRIHIMPSMNP 127

Query: 131 DGWQLATDTGGKDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQLSA 190
           DG++ A       Y IGR N ++ DLNRNFPD       FE   +S              
Sbjct: 128 DGFE-AVKKPDCYYSIGRENYNQYDLNRNFPDA------FEYNNVSR------------- 167

Query: 191 PLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSAS--PDDETFKE 248
             +PET AVM+W+ +  FVLSA +HGG LVA+YP+D     A+ A YS S  PDD+ F+ 
Sbjct: 168 --QPETVAVMKWLKTETFVLSANLHGGALVASYPFDNG-VQATGALYSRSLTPDDDVFQY 224

Query: 249 LAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATN 308
           LA TYA  + +M    ++G      D+         GVTNG +WY L+GGMQD+NY+   
Sbjct: 225 LAHTYASRNPNM----KKG------DECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQ 274

Query: 309 AFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGF-IPNAIISV 367
            FEITLEL C KYP  E L + WN N+ +L+EY+ + H+GVKG V D  G  +PN I+ V
Sbjct: 275 CFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEV 334

Query: 368 VNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVP-KNQKSAII 426
            +       P R    T  YG+YY LL PG Y I  T  GH      V +P K+Q  + +
Sbjct: 335 QD--RKHICPYR----TNKYGEYYLLLLPGSYIINVTVPGHDPHITKVIIPEKSQNFSAL 388

Query: 427 LDFRLEEFQGK 437
               L  FQG+
Sbjct: 389 KKDILLPFQGQ 399


>BC022276-1|AAH22276.1|  443|Homo sapiens carboxypeptidase M
           protein.
          Length = 443

 Score =  280 bits (687), Expect = 7e-75
 Identities = 178/431 (41%), Positives = 240/431 (55%), Gaps = 45/431 (10%)

Query: 11  LLLTVSAEFQWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGF 70
           LLL + A   + +H  E +   L+ V  N  ++T ++++ + SV    L+V+   + P  
Sbjct: 10  LLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGK-SVKGRNLWVLVVGRFPKE 68

Query: 71  HRPYIPEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNP 130
           HR  IPE KY+ N+HG+E +GRELLL L  YL     K DPEI  LI +TRIH++PSMNP
Sbjct: 69  HRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGK-DPEITNLINSTRIHIMPSMNP 127

Query: 131 DGWQLATDTGGKDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQLSA 190
           DG++ A       Y IGR N ++ DLNRNFPD       FE   +S              
Sbjct: 128 DGFE-AVKKPDCYYSIGRENYNQYDLNRNFPDA------FEYNNVSR------------- 167

Query: 191 PLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSAS--PDDETFKE 248
             +PET AVM+W+ +  FVLSA +HGG LVA+YP+D     A+ A YS S  PDD+ F+ 
Sbjct: 168 --QPETVAVMKWLKTETFVLSANLHGGALVASYPFDNG-VQATGALYSRSLTPDDDVFQY 224

Query: 249 LAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATN 308
           LA TYA  + +M    ++G      D+         GVTNG +WY L+GGMQD+NY+   
Sbjct: 225 LAHTYASRNPNM----KKG------DECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQ 274

Query: 309 AFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGF-IPNAIISV 367
            FEITLEL C KYP  E L + WN N+ +L+EY+ + H+GVKG V D  G  +PN I+ V
Sbjct: 275 CFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEV 334

Query: 368 VNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVP-KNQKSAII 426
            +       P R    T  YG+YY LL PG Y I  T  GH      V +P K+Q  + +
Sbjct: 335 QD--RKHICPYR----TNKYGEYYLLLLPGSYIINVTVPGHDPHITKVIIPEKSQNFSAL 388

Query: 427 LDFRLEEFQGK 437
               L  FQG+
Sbjct: 389 KKDILLPFQGQ 399


>AF368463-1|AAK69717.1|  443|Homo sapiens carboxypeptidase M
           protein.
          Length = 443

 Score =  280 bits (687), Expect = 7e-75
 Identities = 178/431 (41%), Positives = 240/431 (55%), Gaps = 45/431 (10%)

Query: 11  LLLTVSAEFQWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGF 70
           LLL + A   + +H  E +   L+ V  N  ++T ++++ + SV    L+V+   + P  
Sbjct: 10  LLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGK-SVKGRNLWVLVVGRFPKE 68

Query: 71  HRPYIPEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNP 130
           HR  IPE KY+ N+HG+E +GRELLL L  YL     K DPEI  LI +TRIH++PSMNP
Sbjct: 69  HRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGK-DPEITNLINSTRIHIMPSMNP 127

Query: 131 DGWQLATDTGGKDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQLSA 190
           DG++ A       Y IGR N ++ DLNRNFPD       FE   +S              
Sbjct: 128 DGFE-AVKKPDCYYSIGRENYNQYDLNRNFPDA------FEYNNVSR------------- 167

Query: 191 PLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSAS--PDDETFKE 248
             +PET AVM+W+ +  FVLSA +HGG LVA+YP+D     A+ A YS S  PDD+ F+ 
Sbjct: 168 --QPETVAVMKWLKTETFVLSANLHGGALVASYPFDNG-VQATGALYSRSLTPDDDVFQY 224

Query: 249 LAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATN 308
           LA TYA  + +M    ++G      D+         GVTNG +WY L+GGMQD+NY+   
Sbjct: 225 LAHTYASRNPNM----KKG------DECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQ 274

Query: 309 AFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGF-IPNAIISV 367
            FEITLEL C KYP  E L + WN N+ +L+EY+ + H+GVKG V D  G  +PN I+ V
Sbjct: 275 CFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEV 334

Query: 368 VNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVP-KNQKSAII 426
            +       P R    T  YG+YY LL PG Y I  T  GH      V +P K+Q  + +
Sbjct: 335 QD--RKHICPYR----TNKYGEYYLLLLPGSYIINVTVPGHDPHITKVIIPEKSQNFSAL 388

Query: 427 LDFRLEEFQGK 437
               L  FQG+
Sbjct: 389 KKDILLPFQGQ 399


>AF262947-1|AAG47641.1|  443|Homo sapiens carboxypeptidase M
           protein.
          Length = 443

 Score =  280 bits (687), Expect = 7e-75
 Identities = 178/431 (41%), Positives = 240/431 (55%), Gaps = 45/431 (10%)

Query: 11  LLLTVSAEFQWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGF 70
           LLL + A   + +H  E +   L+ V  N  ++T ++++ + SV    L+V+   + P  
Sbjct: 10  LLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGK-SVKGRNLWVLVVGRFPKE 68

Query: 71  HRPYIPEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNP 130
           HR  IPE KY+ N+HG+E +GRELLL L  YL     K DPEI  LI +TRIH++PSMNP
Sbjct: 69  HRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGK-DPEITNLINSTRIHIMPSMNP 127

Query: 131 DGWQLATDTGGKDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHLLKDLTQLSA 190
           DG++ A       Y IGR N ++ DLNRNFPD       FE   +S              
Sbjct: 128 DGFE-AVKKPDCYYSIGRENYNQYDLNRNFPDA------FEYNNVSR------------- 167

Query: 191 PLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKTGASAAEYSAS--PDDETFKE 248
             +PET AVM+W+ +  FVLSA +HGG LVA+YP+D     A+ A YS S  PDD+ F+ 
Sbjct: 168 --QPETVAVMKWLKTETFVLSANLHGGALVASYPFDNG-VQATGALYSRSLTPDDDVFQY 224

Query: 249 LAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATN 308
           LA TYA  + +M    ++G      D+         GVTNG +WY L+GGMQD+NY+   
Sbjct: 225 LAHTYASRNPNM----KKG------DECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQ 274

Query: 309 AFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGF-IPNAIISV 367
            FEITLEL C KYP  E L + WN N+ +L+EY+ + H+GVKG V D  G  +PN I+ V
Sbjct: 275 CFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEV 334

Query: 368 VNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSVP-KNQKSAII 426
            +       P R    T  YG+YY LL PG Y I  T  GH      V +P K+Q  + +
Sbjct: 335 QD--RKHICPYR----TNKYGEYYLLLLPGSYIINVTVPGHDPHITKVIIPEKSQNFSAL 388

Query: 427 LDFRLEEFQGK 437
               L  FQG+
Sbjct: 389 KKDILLPFQGQ 399


>D86479-1|BAA13094.1|  845|Homo sapiens AEBP1 protein.
          Length = 845

 Score =  275 bits (674), Expect = 3e-73
 Identities = 155/426 (36%), Positives = 242/426 (56%), Gaps = 41/426 (9%)

Query: 18  EFQWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPE 77
           +  ++HH+ +++  +++ V+  CP ITR Y+L + S   + +Y +E +  PG H    PE
Sbjct: 246 DLDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSR-GLKIYAMEISDNPGEHELGEPE 304

Query: 78  AKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLAT 137
            +Y   IHGNEVLGRELLL L  YLC +YR  +P +++L+ +TRIHL+PS+NPDG+++A 
Sbjct: 305 FRYTAGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAA 364

Query: 138 DTGGK--DYLIGRTNNHEVDLNRNFPDLDAITFDF-ERQGLSH---NNHLLKDLTQLS-- 189
             G +  ++ +G       D+  +FPDL+++ +   ER+ + +   NN+L      LS  
Sbjct: 365 QMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPD 424

Query: 190 APLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKT--------GASAA------ 235
           A +  E RA++ W+   PFVL A ++GG+ + +YPYD ++T         A AA      
Sbjct: 425 ATVSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDE 484

Query: 236 ----EYSASPDDETFKELAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAA 291
               E   +PD   F+ LA+++A AH  +  P R GC         Y  G   G+ NGA 
Sbjct: 485 DEVSEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQ-----DYTGGM--GIVNGAK 537

Query: 292 WYSLKGGMQDFNYLATNAFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKG 351
           W    G + DF+YL TN  E++  LGC+K+P    L  EW  N+EAL+ ++ + H G+KG
Sbjct: 538 WNPRTGTINDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKG 597

Query: 352 VVSDSKGFIPNAIISVVNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQA 411
           VV+D +G      I + N T SV+  I H V T   GDY+R+L PG+Y +TA   G+  +
Sbjct: 598 VVTDEQG------IPIANATISVS-GINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPS 650

Query: 412 SRMVSV 417
           ++  +V
Sbjct: 651 AKTCNV 656


>BC038588-1|AAH38588.1| 1158|Homo sapiens AE binding protein 1
           protein.
          Length = 1158

 Score =  275 bits (674), Expect = 3e-73
 Identities = 155/426 (36%), Positives = 242/426 (56%), Gaps = 41/426 (9%)

Query: 18  EFQWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPE 77
           +  ++HH+ +++  +++ V+  CP ITR Y+L + S   + +Y +E +  PG H    PE
Sbjct: 559 DLDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSR-GLKIYAMEISDNPGEHELGEPE 617

Query: 78  AKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLAT 137
            +Y   IHGNEVLGRELLL L  YLC +YR  +P +++L+ +TRIHL+PS+NPDG+++A 
Sbjct: 618 FRYTAGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAA 677

Query: 138 DTGGK--DYLIGRTNNHEVDLNRNFPDLDAITFDF-ERQGLSH---NNHLLKDLTQLS-- 189
             G +  ++ +G       D+  +FPDL+++ +   ER+ + +   NN+L      LS  
Sbjct: 678 QMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPD 737

Query: 190 APLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKT--------GASAA------ 235
           A +  E RA++ W+   PFVL A ++GG+ + +YPYD ++T         A AA      
Sbjct: 738 ATVSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDE 797

Query: 236 ----EYSASPDDETFKELAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAA 291
               E   +PD   F+ LA+++A AH  +  P R GC         Y  G   G+ NGA 
Sbjct: 798 DEVSEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQ-----DYTGGM--GIVNGAK 850

Query: 292 WYSLKGGMQDFNYLATNAFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKG 351
           W    G + DF+YL TN  E++  LGC+K+P    L  EW  N+EAL+ ++ + H G+KG
Sbjct: 851 WNPRTGTINDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKG 910

Query: 352 VVSDSKGFIPNAIISVVNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQA 411
           VV+D +G      I + N T SV+  I H V T   GDY+R+L PG+Y +TA   G+  +
Sbjct: 911 VVTDEQG------IPIANATISVS-GINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPS 963

Query: 412 SRMVSV 417
           ++  +V
Sbjct: 964 AKTCNV 969


>AF053944-1|AAC25585.1| 1158|Homo sapiens aortic
           carboxypeptidase-like protein ACLP protein.
          Length = 1158

 Score =  275 bits (674), Expect = 3e-73
 Identities = 155/426 (36%), Positives = 242/426 (56%), Gaps = 41/426 (9%)

Query: 18  EFQWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPE 77
           +  ++HH+ +++  +++ V+  CP ITR Y+L + S   + +Y +E +  PG H    PE
Sbjct: 559 DLDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSR-GLKIYAMEISDNPGEHELGEPE 617

Query: 78  AKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLAT 137
            +Y   IHGNEVLGRELLL L  YLC +YR  +P +++L+ +TRIHL+PS+NPDG+++A 
Sbjct: 618 FRYTAGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAA 677

Query: 138 DTGGK--DYLIGRTNNHEVDLNRNFPDLDAITFDF-ERQGLSH---NNHLLKDLTQLS-- 189
             G +  ++ +G       D+  +FPDL+++ +   ER+ + +   NN+L      LS  
Sbjct: 678 QMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPD 737

Query: 190 APLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKT--------GASAA------ 235
           A +  E RA++ W+   PFVL A ++GG+ + +YPYD ++T         A AA      
Sbjct: 738 ATVSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDE 797

Query: 236 ----EYSASPDDETFKELAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAA 291
               E   +PD   F+ LA+++A AH  +  P R GC         Y  G   G+ NGA 
Sbjct: 798 DEVSEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQ-----DYTGGM--GIVNGAK 850

Query: 292 WYSLKGGMQDFNYLATNAFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKG 351
           W    G + DF+YL TN  E++  LGC+K+P    L  EW  N+EAL+ ++ + H G+KG
Sbjct: 851 WNPRTGTINDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKG 910

Query: 352 VVSDSKGFIPNAIISVVNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQA 411
           VV+D +G      I + N T SV+  I H V T   GDY+R+L PG+Y +TA   G+  +
Sbjct: 911 VVTDEQG------IPIANATISVS-GINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPS 963

Query: 412 SRMVSV 417
           ++  +V
Sbjct: 964 AKTCNV 969


>AB209744-1|BAD92981.1| 1172|Homo sapiens adipocyte enhancer binding
           protein 1 precursor variant protein.
          Length = 1172

 Score =  275 bits (674), Expect = 3e-73
 Identities = 155/426 (36%), Positives = 242/426 (56%), Gaps = 41/426 (9%)

Query: 18  EFQWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPE 77
           +  ++HH+ +++  +++ V+  CP ITR Y+L + S   + +Y +E +  PG H    PE
Sbjct: 573 DLDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSR-GLKIYAMEISDNPGEHELGEPE 631

Query: 78  AKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLAT 137
            +Y   IHGNEVLGRELLL L  YLC +YR  +P +++L+ +TRIHL+PS+NPDG+++A 
Sbjct: 632 FRYTAGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAA 691

Query: 138 DTGGK--DYLIGRTNNHEVDLNRNFPDLDAITFDF-ERQGLSH---NNHLLKDLTQLS-- 189
             G +  ++ +G       D+  +FPDL+++ +   ER+ + +   NN+L      LS  
Sbjct: 692 QMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPD 751

Query: 190 APLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKT--------GASAA------ 235
           A +  E RA++ W+   PFVL A ++GG+ + +YPYD ++T         A AA      
Sbjct: 752 ATVSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDE 811

Query: 236 ----EYSASPDDETFKELAMTYALAHADMASPTRRGCHTTSSDDVSYNFGKQGGVTNGAA 291
               E   +PD   F+ LA+++A AH  +  P R GC         Y  G   G+ NGA 
Sbjct: 812 DEVSEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQ-----DYTGGM--GIVNGAK 864

Query: 292 WYSLKGGMQDFNYLATNAFEITLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKG 351
           W    G + DF+YL TN  E++  LGC+K+P    L  EW  N+EAL+ ++ + H G+KG
Sbjct: 865 WNPRTGTINDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKG 924

Query: 352 VVSDSKGFIPNAIISVVNCTGSVTKPIRHDVTTGPYGDYYRLLTPGQYEITATHTGHFQA 411
           VV+D +G      I + N T SV+  I H V T   GDY+R+L PG+Y +TA   G+  +
Sbjct: 925 VVTDEQG------IPIANATISVS-GINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPS 977

Query: 412 SRMVSV 417
           ++  +V
Sbjct: 978 AKTCNV 983


>AK127541-1|BAC87026.1|  733|Homo sapiens protein ( Homo sapiens
           cDNA FLJ45634 fis, clone CHONS2002829, moderately
           similar to Homo sapiens adipocyte enhancer binding
           protein 1 (AEBP1). ).
          Length = 733

 Score =  272 bits (667), Expect = 2e-72
 Identities = 157/442 (35%), Positives = 248/442 (56%), Gaps = 42/442 (9%)

Query: 2   ALYSFVCFSLLLTVSAEFQWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYV 61
           A+YS+   + ++    +  ++HH+ + +  +++ V+  CP ITR Y+L + S   + +Y 
Sbjct: 119 AVYSYYAQNEVVATD-DLDFRHHSYKGMRQLMKVVNEECPTITRTYSLGKSSR-GLKIYA 176

Query: 62  IEFAQVPGFHRPYIPEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTR 121
           +E +  PG H    PE +Y   IHGNEVLGRELLL L  YLC +YR  +P +++L+ +TR
Sbjct: 177 MEISDNPGEHELGEPEFRYTAGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTR 236

Query: 122 IHLLPSMNPDGWQLATDTGGK--DYLIGRTNNHEVDLNRNFPDLDAITFDFER-QGLSH- 177
           IHL+PS+NPDG+++A   G +  ++ +G       D+  +FPDL+++ +  E  + + + 
Sbjct: 237 IHLVPSLNPDGYEVAAQMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEEGKWVPYR 296

Query: 178 --NNHLLKDLTQLS--APLEPETRAVMRWIMSTPFVLSAAIHGGDLVANYPYDESKT--- 230
             NN+L      LS  A +  E RA++ W+   PFVL A ++GG+ + +YPYD ++T   
Sbjct: 297 VPNNNLPIPERYLSPDATVSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQ 356

Query: 231 -----GASAA----------EYSASPDDETFKELAMTYALAHADMASPTRRGCHTTSSDD 275
                 A AA          E   +PD   F+ LA+++A AH  +  P R GC       
Sbjct: 357 EQLLAAAMAAARGEDEDEVSEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQ---- 412

Query: 276 VSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLELGCEKYPSAELLETEWNRNR 335
             Y  G   G+ NGA W    G + DF+YL TN  E++  LGC+K+P    L  EW  N+
Sbjct: 413 -DYTGGM--GIVNGAKWNPRTGTINDFSYLHTNCLELSFYLGCDKFPHEGELPREWENNK 469

Query: 336 EALVEYLWKAHIGVKGVVSDSKGFIPNAIISVVNCTGSVTKPIRHDVTTGPYGDYYRLLT 395
           EAL+ ++ + H G+KGVV+D +G      I + N T SV+  I H V T   GDY+R+L 
Sbjct: 470 EALLTFMEQVHRGIKGVVTDEQG------IPIANATISVS-GINHGVKTASGGDYWRILN 522

Query: 396 PGQYEITATHTGHFQASRMVSV 417
           PG+Y +TA   G+  +++  +V
Sbjct: 523 PGEYRVTAHAEGYTPSAKTCNV 544


>AL441886-2|CAI13077.1|  204|Homo sapiens carboxypeptidase N,
           polypeptide 1, 50kD protein.
          Length = 204

 Score =  174 bits (424), Expect = 5e-43
 Identities = 98/215 (45%), Positives = 129/215 (60%), Gaps = 25/215 (11%)

Query: 208 FVLSAAIHGGDLVANYPYDES----KTGASAAEYSASPDDETFKELAMTYALAHADMASP 263
           FVLSA +HGG +VANYPYD+S      G      + +PDD+ F++LA  Y+ AH  M   
Sbjct: 6   FVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKVYSYAHGWMFQG 65

Query: 264 TRRGCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLELGCEKYPS 323
              G +               G+TNGA+WYSL  GMQDFNYL TN FEITLEL C+K+P 
Sbjct: 66  WNCGDYFPD------------GITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPP 113

Query: 324 AELLETEWNRNREALVEYLWKAHIGVKGVVSDSK-GFIPNAIISVVNCTGSVTKPIRHDV 382
            E L+ EW  NREAL+++L + H G+KG+V D     + NA+ISV          I HDV
Sbjct: 114 EEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVISV--------SGINHDV 165

Query: 383 TTGPYGDYYRLLTPGQYEITATHTGHFQASRMVSV 417
           T+G +GDY+RLL PG Y ++AT  G+   +  V+V
Sbjct: 166 TSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTV 200


>BC027623-1|AAH27623.1|  224|Homo sapiens CPXM2 protein protein.
          Length = 224

 Score =  153 bits (370), Expect = 2e-36
 Identities = 77/180 (42%), Positives = 108/180 (60%), Gaps = 16/180 (8%)

Query: 207 PFVLSAAIHGGDLVANYPYDESKTGASAAEYSASPDDETFKELAMTYALAHADMASPTRR 266
           PFVL   + GG+LV  YPYD  ++     E++ +PDD  F+ LA +YA  H  M    RR
Sbjct: 5   PFVLGGNLQGGELVVAYPYDLVRSPWKTQEHTPTPDDHVFRWLAYSYASTHRLMTDARRR 64

Query: 267 GCHTTSSDDVSYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLELGCEKYPSAEL 326
            CHT        +F K+ G  NGA+W+++ G + DF+YL TN FE+++ +GC+KYP    
Sbjct: 65  VCHTE-------DFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVGCDKYPHESQ 117

Query: 327 LETEWNRNREALVEYLWKAHIGVKGVVSDSKG-FIPNAIISVVNCTGSVTKPIRHDVTTG 385
           L  EW  NRE+L+ ++ + H G+KG+V DS G  IPNAIISV        + I HD+ TG
Sbjct: 118 LPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAIISV--------EGINHDIRTG 169


>AK075527-1|BAC11672.1|  477|Homo sapiens protein ( Homo sapiens
           cDNA PSEC0226 fis, clone HEMBA1005833, moderately
           similar to Mus musculus carboxypeptidase X2 mRNA. ).
          Length = 477

 Score =  142 bits (345), Expect = 2e-33
 Identities = 70/172 (40%), Positives = 107/172 (62%), Gaps = 7/172 (4%)

Query: 16  SAEFQWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYI 75
           S    ++HHN + +  ++++V   CPNITRIY++ + S   + LYV+E +  PG H    
Sbjct: 292 SDPLDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGK-SYQGLKLYVMEMSDKPGEHELGE 350

Query: 76  PEAKYIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQL 135
           PE +Y+  +HGNE LGRELLL L  +LC ++ + +P +  L++  RIHLLPSMNPDG+++
Sbjct: 351 PEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEI 410

Query: 136 ATDTGGK--DYLIGRTNNHEVDLNRNFPDLDAITFDFERQG-LSH---NNHL 181
           A   G +   +  GR NN  +DLN NF DL+   ++ +  G + H   N+HL
Sbjct: 411 AYHRGSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHL 462


>AK056317-1|BAB71147.1|  364|Homo sapiens protein ( Homo sapiens
           cDNA FLJ31755 fis, clone NT2RI2007498, highly similar to
           Homo sapiens carboxypeptidase Z precursor, mRNA. ).
          Length = 364

 Score =  139 bits (336), Expect = 2e-32
 Identities = 69/164 (42%), Positives = 98/164 (59%), Gaps = 3/164 (1%)

Query: 20  QWKHHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAK 79
           ++ HH+  ++  VL+   + C ++ R Y++   S     L VIEF+  PG H    PE K
Sbjct: 184 RFSHHSYAQMVRVLRRTASRCAHVARTYSIGR-SFDGRELLVIEFSSRPGQHELMEPEVK 242

Query: 80  YIGNIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDT 139
            IGNIHGNEV GRE+L+ LA YLC +Y   +P I+ L+  TRIHLLPSMNPDG+++A   
Sbjct: 243 LIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAE 302

Query: 140 GG--KDYLIGRTNNHEVDLNRNFPDLDAITFDFERQGLSHNNHL 181
           G     +  GR N   +DLNRNFPDL +  +       + ++H+
Sbjct: 303 GAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHI 346


>BC052289-1|AAH52289.1|  421|Homo sapiens CPA4 protein protein.
          Length = 421

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 6/129 (4%)

Query: 23  HHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKYIG 82
           +H+ E +   +  +  + P++ R   +   S  N P+YV++F+   G  RP +       
Sbjct: 123 YHSLEAIYHEMDNIAADFPDLARRVKIGH-SFENRPMYVLKFSTGKGVRRPAV---WLNA 178

Query: 83  NIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDTGGK 142
            IH  E + +   +  A  +   Y++ DP I +++    I LLP  NPDG+ + T T  +
Sbjct: 179 GIHSREWISQATAIWTARKIVSDYQR-DPAITSILEKMDIFLLPVANPDGY-VYTQTQNR 236

Query: 143 DYLIGRTNN 151
            +   R+ N
Sbjct: 237 LWRKTRSRN 245


>AY358699-1|AAQ89062.1|  421|Homo sapiens CPA4 protein.
          Length = 421

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 6/129 (4%)

Query: 23  HHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKYIG 82
           +H+ E +   +  +  + P++ R   +   S  N P+YV++F+   G  RP +       
Sbjct: 123 YHSLEAIYHEMDNIAADFPDLARRVKIGH-SFENRPMYVLKFSTGKGVRRPAV---WLNA 178

Query: 83  NIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDTGGK 142
            IH  E + +   +  A  +   Y++ DP I +++    I LLP  NPDG+ + T T  +
Sbjct: 179 GIHSREWISQATAIWTARKIVSDYQR-DPAITSILEKMDIFLLPVANPDGY-VYTQTQNR 236

Query: 143 DYLIGRTNN 151
            +   R+ N
Sbjct: 237 LWRKTRSRN 245


>AF095719-1|AAF23230.1|  421|Homo sapiens carboxypeptidase A3
           protein.
          Length = 421

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 6/129 (4%)

Query: 23  HHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKYIG 82
           +H+ E +   +  +  + P++ R   +   S  N P+YV++F+   G  RP +       
Sbjct: 123 YHSLEAIYHEMDNIAADFPDLARRVKIGH-SFENRPMYVLKFSTGKGVRRPAV---WLNA 178

Query: 83  NIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGWQLATDTGGK 142
            IH  E + +   +  A  +   Y++ DP I +++    I LLP  NPDG+ + T T  +
Sbjct: 179 GIHSREWISQATAIWTARKIVSDYQR-DPAITSILEKMDIFLLPVANPDGY-VYTQTQNR 236

Query: 143 DYLIGRTNN 151
            +   R+ N
Sbjct: 237 LWRKTRSRN 245


>U19977-1|AAA74425.1|  417|Homo sapiens preprocarboxypeptidase A2
           protein.
          Length = 417

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 30/111 (27%), Positives = 49/111 (44%), Gaps = 7/111 (6%)

Query: 23  HHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKYIG 82
           +H  EE+   +  +    P +     +   S  N P+ V++F+   G  +P I       
Sbjct: 121 YHTLEEISQEMDNLVAEHPGLVSKVNIGS-SFENRPMNVLKFST--GGDKPAI---WLDA 174

Query: 83  NIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGW 133
            IH  E + +   L  A+ +   Y K DP I +++    I LLP  NPDG+
Sbjct: 175 GIHAREWVTQATALWTANKIVSDYGK-DPSITSILDALDIFLLPVTNPDGY 224


>U11700-1|AAA92667.1| 1465|Homo sapiens copper transporting ATPase
            protein.
          Length = 1465

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 4/92 (4%)

Query: 313  TLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGFIPNAIISVVN--C 370
            +L+L C K P  E  E + + + + L       HIG+     DS    P   +S V+   
Sbjct: 1370 SLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVSQVS 1429

Query: 371  TGSVT--KPIRHDVTTGPYGDYYRLLTPGQYE 400
              S+T  KP RH       GD + LL  G+ E
Sbjct: 1430 LSSLTSDKPSRHSAAADDDGDKWSLLLNGRDE 1461


>U03464-1|AAB52902.1| 1465|Homo sapiens ATP7B protein.
          Length = 1465

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 4/92 (4%)

Query: 313  TLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGFIPNAIISVVN--C 370
            +L+L C K P  E  E + + + + L       HIG+     DS    P   +S V+   
Sbjct: 1370 SLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVSQVS 1429

Query: 371  TGSVT--KPIRHDVTTGPYGDYYRLLTPGQYE 400
              S+T  KP RH       GD + LL  G+ E
Sbjct: 1430 LSSLTSDKPSRHSAAADDDGDKWSLLLNGRDE 1461


>L25591-2|AAA79212.1|  762|Homo sapiens protein ( Homo sapiens (PWD)
           gene mRNA, 3' end. ).
          Length = 762

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 4/92 (4%)

Query: 313 TLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGFIPNAIISVVN--C 370
           +L+L C K P  E  E + + + + L       HIG+     DS    P   +S V+   
Sbjct: 667 SLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVSQVS 726

Query: 371 TGSVT--KPIRHDVTTGPYGDYYRLLTPGQYE 400
             S+T  KP RH       GD + LL  G+ E
Sbjct: 727 LSSLTSDKPSRHSAAADDDGDKWSLLLNGRDE 758


>DQ015922-1|AAY41166.1| 1354|Homo sapiens Wilson's disease protein
            protein.
          Length = 1354

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 4/92 (4%)

Query: 313  TLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGFIPNAIISVVN--C 370
            +L+L C K P  E  E + + + + L       HIG+     DS    P   +S V+   
Sbjct: 1259 SLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVSQVS 1318

Query: 371  TGSVT--KPIRHDVTTGPYGDYYRLLTPGQYE 400
              S+T  KP RH       GD + LL  G+ E
Sbjct: 1319 LSSLTSDKPSRHSAAADDDGDKWSLLLNGRDE 1350


>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone RP11-465I11 on chromosome 1. ).
          Length = 5635

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 7/60 (11%)

Query: 366  SVVNCTGS-VTKPIRHDVTTG----PYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKN 420
            +V+ CT S V  P  H    G    P GD YR+L+ G  EI AT   H  A R   V +N
Sbjct: 3914 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNH--AGRYTCVARN 3971


>BT007403-1|AAP36067.1|  417|Homo sapiens carboxypeptidase A2
           (pancreatic) protein.
          Length = 417

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 30/111 (27%), Positives = 49/111 (44%), Gaps = 7/111 (6%)

Query: 23  HHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKYIG 82
           +H  EE+   +  +    P +     +   S  N P+ V++F+   G  +P I       
Sbjct: 121 YHTLEEISQEMDNLVAEHPGLVSKVNIGS-SFENRPMNVLKFST--GGDKPAI---WLDA 174

Query: 83  NIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGW 133
            IH  E + +   L  A+ +   Y K DP I +++    I LLP  NPDG+
Sbjct: 175 GIHAREWVTQATALWTANKIVSDYGK-DPSITSILDALDIFLLPVTNPDGY 224


>BC117200-1|AAI17201.1| 1035|Homo sapiens ATP7B protein protein.
          Length = 1035

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 4/92 (4%)

Query: 313  TLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGFIPNAIISVVN--C 370
            +L+L C K P  E  E + + + + L       HIG+     DS    P   +S V+   
Sbjct: 940  SLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVSQVS 999

Query: 371  TGSVT--KPIRHDVTTGPYGDYYRLLTPGQYE 400
              S+T  KP RH       GD + LL  G+ E
Sbjct: 1000 LSSLTSDKPSRHSAAADDDGDKWSLLLNGRDE 1031


>BC015140-1|AAH15140.1|  417|Homo sapiens carboxypeptidase A2
           (pancreatic) protein.
          Length = 417

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 30/111 (27%), Positives = 49/111 (44%), Gaps = 7/111 (6%)

Query: 23  HHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKYIG 82
           +H  EE+   +  +    P +     +   S  N P+ V++F+   G  +P I       
Sbjct: 121 YHTLEEISQEMDNLVAEHPGLVSKVNIGS-SFENRPMNVLKFST--GGDKPAI---WLDA 174

Query: 83  NIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGW 133
            IH  E + +   L  A+ +   Y K DP I +++    I LLP  NPDG+
Sbjct: 175 GIHAREWVTQATALWTANKIVSDYGK-DPSITSILDALDIFLLPVTNPDGY 224


>BC014571-1|AAH14571.1|  417|Homo sapiens carboxypeptidase A2
           (pancreatic) protein.
          Length = 417

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 30/111 (27%), Positives = 49/111 (44%), Gaps = 7/111 (6%)

Query: 23  HHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKYIG 82
           +H  EE+   +  +    P +     +   S  N P+ V++F+   G  +P I       
Sbjct: 121 YHTLEEISQEMDNLVAEHPGLVSKVNIGS-SFENRPMNVLKFST--GGDKPAI---WLDA 174

Query: 83  NIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGW 133
            IH  E + +   L  A+ +   Y K DP I +++    I LLP  NPDG+
Sbjct: 175 GIHAREWVTQATALWTANKIVSDYGK-DPSITSILDALDIFLLPVTNPDGY 224


>BC007009-1|AAH07009.1|  417|Homo sapiens carboxypeptidase A2
           (pancreatic) protein.
          Length = 417

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 30/111 (27%), Positives = 49/111 (44%), Gaps = 7/111 (6%)

Query: 23  HHNNEELPLVLQEVHNNCPNITRIYALSEPSVCNVPLYVIEFAQVPGFHRPYIPEAKYIG 82
           +H  EE+   +  +    P +     +   S  N P+ V++F+   G  +P I       
Sbjct: 121 YHTLEEISQEMDNLVAEHPGLVSKVNIGS-SFENRPMNVLKFST--GGDKPAI---WLDA 174

Query: 83  NIHGNEVLGRELLLGLAHYLCDQYRKNDPEIKALITNTRIHLLPSMNPDGW 133
            IH  E + +   L  A+ +   Y K DP I +++    I LLP  NPDG+
Sbjct: 175 GIHAREWVTQATALWTANKIVSDYGK-DPSITSILDALDIFLLPVTNPDGY 224


>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-268N14 on chromosome 1. ).
          Length = 5635

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 7/60 (11%)

Query: 366  SVVNCTGS-VTKPIRHDVTTG----PYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKN 420
            +V+ CT S V  P  H    G    P GD YR+L+ G  EI AT   H  A R   V +N
Sbjct: 3914 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNH--AGRYTCVARN 3971


>AL162377-2|CAI13428.1| 1465|Homo sapiens Atp7b protein.
          Length = 1465

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 4/92 (4%)

Query: 313  TLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGFIPNAIISVVN--C 370
            +L+L C K P  E  E + + + + L       HIG+     DS    P   +S V+   
Sbjct: 1370 SLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVSQVS 1429

Query: 371  TGSVT--KPIRHDVTTGPYGDYYRLLTPGQYE 400
              S+T  KP RH       GD + LL  G+ E
Sbjct: 1430 LSSLTSDKPSRHSAAADDDGDKWSLLLNGRDE 1461


>AL139082-1|CAI12888.1| 1465|Homo sapiens Atp7b protein.
          Length = 1465

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 4/92 (4%)

Query: 313  TLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGFIPNAIISVVN--C 370
            +L+L C K P  E  E + + + + L       HIG+     DS    P   +S V+   
Sbjct: 1370 SLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVSQVS 1429

Query: 371  TGSVT--KPIRHDVTTGPYGDYYRLLTPGQYE 400
              S+T  KP RH       GD + LL  G+ E
Sbjct: 1430 LSSLTSDKPSRHSAAADDDGDKWSLLLNGRDE 1461


>AL138821-2|CAI13743.1| 1465|Homo sapiens Atp7b protein.
          Length = 1465

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 4/92 (4%)

Query: 313  TLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGFIPNAIISVVN--C 370
            +L+L C K P  E  E + + + + L       HIG+     DS    P   +S V+   
Sbjct: 1370 SLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVSQVS 1429

Query: 371  TGSVT--KPIRHDVTTGPYGDYYRLLTPGQYE 400
              S+T  KP RH       GD + LL  G+ E
Sbjct: 1430 LSSLTSDKPSRHSAAADDDGDKWSLLLNGRDE 1461


>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-77J13 on chromosome 1. ).
          Length = 5635

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 7/60 (11%)

Query: 366  SVVNCTGS-VTKPIRHDVTTG----PYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKN 420
            +V+ CT S V  P  H    G    P GD YR+L+ G  EI AT   H  A R   V +N
Sbjct: 3914 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNH--AGRYTCVARN 3971


>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-164L12 on chromosome 1. ).
          Length = 5635

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 7/60 (11%)

Query: 366  SVVNCTGS-VTKPIRHDVTTG----PYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKN 420
            +V+ CT S V  P  H    G    P GD YR+L+ G  EI AT   H  A R   V +N
Sbjct: 3914 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNH--AGRYTCVARN 3971


>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-174L6 on chromosome 1. ).
          Length = 5635

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 7/60 (11%)

Query: 366  SVVNCTGS-VTKPIRHDVTTG----PYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKN 420
            +V+ CT S V  P  H    G    P GD YR+L+ G  EI AT   H  A R   V +N
Sbjct: 3914 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNH--AGRYTCVARN 3971


>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-153O3 on chromosome 1. ).
          Length = 5635

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 7/60 (11%)

Query: 366  SVVNCTGS-VTKPIRHDVTTG----PYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKN 420
            +V+ CT S V  P  H    G    P GD YR+L+ G  EI AT   H  A R   V +N
Sbjct: 3914 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNH--AGRYTCVARN 3971


>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
          Length = 5635

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 7/60 (11%)

Query: 366  SVVNCTGS-VTKPIRHDVTTG----PYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKN 420
            +V+ CT S V  P  H    G    P GD YR+L+ G  EI AT   H  A R   V +N
Sbjct: 3914 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNH--AGRYTCVARN 3971


>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
          Length = 5635

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 7/60 (11%)

Query: 366  SVVNCTGS-VTKPIRHDVTTG----PYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKN 420
            +V+ CT S V  P  H    G    P GD YR+L+ G  EI AT   H  A R   V +N
Sbjct: 3914 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNH--AGRYTCVARN 3971


>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
          Length = 2673

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 7/60 (11%)

Query: 366  SVVNCTGS-VTKPIRHDVTTG----PYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKN 420
            +V+ CT S V  P  H    G    P GD YR+L+ G  EI AT   H  A R   V +N
Sbjct: 952  AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNH--AGRYTCVARN 1009


>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
          Length = 5636

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 7/60 (11%)

Query: 366  SVVNCTGS-VTKPIRHDVTTG----PYGDYYRLLTPGQYEITATHTGHFQASRMVSVPKN 420
            +V+ CT S V  P  H    G    P GD YR+L+ G  EI AT   H  A R   V +N
Sbjct: 3915 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNH--AGRYTCVARN 3972


>AB209461-1|BAD92698.1|  662|Homo sapiens ATPase, Cu++ transporting,
           beta polypeptide isoform a variant protein.
          Length = 662

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 4/92 (4%)

Query: 313 TLELGCEKYPSAELLETEWNRNREALVEYLWKAHIGVKGVVSDSKGFIPNAIISVVN--C 370
           +L+L C K P  E  E + + + + L       HIG+     DS    P   +S V+   
Sbjct: 567 SLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVSQVS 626

Query: 371 TGSVT--KPIRHDVTTGPYGDYYRLLTPGQYE 400
             S+T  KP RH       GD + LL  G+ E
Sbjct: 627 LSSLTSDKPSRHSAAADDDGDKWSLLLNGRDE 658


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.317    0.134    0.406 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 75,689,054
Number of Sequences: 224733
Number of extensions: 3319688
Number of successful extensions: 5685
Number of sequences better than 10.0: 61
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 5420
Number of HSP's gapped (non-prelim): 94
length of query: 483
length of database: 73,234,838
effective HSP length: 93
effective length of query: 390
effective length of database: 52,334,669
effective search space: 20410520910
effective search space used: 20410520910
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 67 (31.1 bits)

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