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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000300-TA|BGIBMGA000300-PA|IPR005835|Nucleotidyl
transferase
         (451 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC018728-1|AAH18728.1|  401|Homo sapiens EIF2B3 protein protein.      252   3e-66
AL136380-6|CAI23132.1|  412|Homo sapiens eukaryotic translation ...   252   3e-66
AL136380-5|CAI23131.1|  452|Homo sapiens eukaryotic translation ...   252   3e-66
AF257077-1|AAF91351.1|  452|Homo sapiens eukaryotic translation ...   252   3e-66
AK024006-1|BAB14770.1|  452|Homo sapiens NA.  protein.                251   4e-66
AL136380-7|CAI23133.1|  197|Homo sapiens eukaryotic translation ...   140   9e-33
CR457285-1|CAG33566.1|  283|Homo sapiens EIF2B3 protein.              114   7e-25
AK022399-1|BAB14027.1|  283|Homo sapiens protein ( Homo sapiens ...   114   7e-25
AL136380-3|CAI23129.1|  221|Homo sapiens eukaryotic translation ...   106   2e-22
BC013590-1|AAH13590.1|  721|Homo sapiens eukaryotic translation ...    51   1e-05
AK091646-1|BAC03712.1|  721|Homo sapiens protein ( Homo sapiens ...    51   1e-05
U23028-1|AAC50646.1|  641|Homo sapiens eIF-2Bepsilon protein.          43   0.002
AK222951-1|BAD96671.1|  420|Homo sapiens GDP-mannose pyrophospho...    36   0.22 
BC007456-1|AAH07456.1|  420|Homo sapiens GDP-mannose pyrophospho...    36   0.39 
AK000999-1|BAA91460.1|  420|Homo sapiens protein ( Homo sapiens ...    36   0.39 
AF135422-1|AAD38517.1|  399|Homo sapiens GDP-mannose pyrophospho...    36   0.39 
AC053503-4|AAY15053.1|  420|Homo sapiens unknown protein.              36   0.39 
BC112897-1|AAI12898.1|  906|Homo sapiens KIAA0350 protein protein.     33   2.7  
AB232668-1|BAF51560.1| 1543|Homo sapiens YY1AP-related protein3 ...    33   2.7  
BC036756-1|AAH36756.1|  377|Homo sapiens guanine nucleotide bind...    32   3.6  
AF493902-1|AAM12616.1|  377|Homo sapiens guanine nucleotide bind...    32   3.6  
AB208821-1|BAD92058.1|  338|Homo sapiens eukaryotic translation ...    32   3.6  
L22075-1|AAA74235.1|  377|Homo sapiens guanine nucleotide regula...    32   4.8  
BX537764-1|CAD97829.1| 1546|Homo sapiens hypothetical protein pr...    32   4.8  
BC115703-1|AAI15704.1| 1529|Homo sapiens gon-4-like (C. elegans)...    32   4.8  
BC114629-1|AAI14630.1| 1529|Homo sapiens gon-4-like (C. elegans)...    32   4.8  
BC036740-1|AAH36740.2|  981|Homo sapiens GON4L protein protein.        32   4.8  
AY335492-1|AAR01262.1| 1529|Homo sapiens GON4L isoform B protein.      32   4.8  
AL139128-5|CAH69947.1| 1529|Homo sapiens novel protein protein.        32   4.8  
AK222851-1|BAD96571.1|  852|Homo sapiens Hypothetical protein DK...    32   4.8  
AK022985-1|BAB14347.1|  725|Homo sapiens protein ( Homo sapiens ...    32   4.8  
BX537849-1|CAD97857.1| 1626|Homo sapiens hypothetical protein pr...    31   6.3  
BC008033-1|AAH08033.1|  360|Homo sapiens GDP-mannose pyrophospho...    31   6.3  
BC001141-1|AAH01141.1|  360|Homo sapiens GDP-mannose pyrophospho...    31   6.3  
AY362728-1|AAR13367.1| 2677|Homo sapiens ataxia/oculomotor aprax...    31   6.3  
AL353701-2|CAM14151.1| 2677|Homo sapiens senataxin protein.            31   6.3  
AL353701-1|CAM14150.1|  670|Homo sapiens senataxin protein.            31   6.3  
AL159997-2|CAI40854.1| 2677|Homo sapiens senataxin protein.            31   6.3  
AL159997-1|CAI40858.2|  670|Homo sapiens senataxin protein.            31   6.3  
AK125448-1|BAC86166.1|  635|Homo sapiens protein ( Homo sapiens ...    31   6.3  
AK024319-1|BAB14882.1|  387|Homo sapiens protein ( Homo sapiens ...    31   6.3  
AF135421-1|AAD38516.1|  360|Homo sapiens GDP-mannose pyrophospho...    31   6.3  
AB014525-1|BAA31600.2| 2663|Homo sapiens KIAA0625 protein protein.     31   6.3  

>BC018728-1|AAH18728.1|  401|Homo sapiens EIF2B3 protein protein.
          Length = 401

 Score =  252 bits (616), Expect = 3e-66
 Identities = 141/410 (34%), Positives = 247/410 (60%), Gaps = 19/410 (4%)

Query: 5   LEFQVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVLDEDK 64
           +EFQ VV+A G GSRM D+  S+ K LLPVG  P++WYPLN+LE++GF++V IVV   D 
Sbjct: 1   MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEV-IVVTTRDV 59

Query: 65  SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSARINTDLLVISGDLITNINLNDV 124
              L A  K  +K+K +++ IP + D GTA+SL+++  ++ TD+LV+S DLIT++ L++V
Sbjct: 60  QKALCAEFK--MKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEV 117

Query: 125 LNLHRKHDACVTTLFFNNGPEEWIELPGPKTKSKP--DRDLVCIDKETERLVFLASASDF 182
           ++L R +DA +  L    G +    +PG K K K    RD + +D   +RL+F+A+ +D 
Sbjct: 118 VDLFRAYDASLAMLM-RKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADL 176

Query: 183 EENVTIPRLLVKKYDALSIYSRLLDAHVYVMKHWILDYIVDSEKFTSIKGEVVPYIVKKQ 242
           +E + I   +++K+  +  ++ L+DAH+Y +K +I+D+++++   TSI+ E++PY+V+KQ
Sbjct: 177 DEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQ 236

Query: 243 LTKPNNLVEKKGTSEKNAEINKGIFDYAIETGY--ERKIREISAYNDHKHGNKGVYFND- 299
            +  ++   ++G  EK  ++ K          +  E     ++ Y+   +  +G  + D 
Sbjct: 237 FSSASS---QQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDL 293

Query: 300 ---TLRCYAHIPSKNTFAIRVNTLSSFYLSNNKILSKWQDLTGSSLFERFHPNSEVKTIQ 356
               +RCY HI  K     RV+TL  +  +N ++      L         H ++++ +  
Sbjct: 294 SRSQVRCYVHI-MKEGLCSRVSTLGLYMEANRQVPKLLSALCPEE--PPVHSSAQIVSKH 350

Query: 357 -IDDNCTVGEKTIINEKTSVKNSFIGSNCNIENKVRLTNCILMNNVTIKE 405
            +  +  +G +T I EK+S+K S IGS+C I+++V +TNC+LMN+VT++E
Sbjct: 351 LVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEE 400


>AL136380-6|CAI23132.1|  412|Homo sapiens eukaryotic translation
           initiation factor 2B, subunit 3 gamma, 58kDa protein.
          Length = 412

 Score =  252 bits (616), Expect = 3e-66
 Identities = 141/410 (34%), Positives = 247/410 (60%), Gaps = 19/410 (4%)

Query: 5   LEFQVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVLDEDK 64
           +EFQ VV+A G GSRM D+  S+ K LLPVG  P++WYPLN+LE++GF++V IVV   D 
Sbjct: 1   MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEV-IVVTTRDV 59

Query: 65  SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSARINTDLLVISGDLITNINLNDV 124
              L A  K  +K+K +++ IP + D GTA+SL+++  ++ TD+LV+S DLIT++ L++V
Sbjct: 60  QKALCAEFK--MKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEV 117

Query: 125 LNLHRKHDACVTTLFFNNGPEEWIELPGPKTKSKP--DRDLVCIDKETERLVFLASASDF 182
           ++L R +DA +  L    G +    +PG K K K    RD + +D   +RL+F+A+ +D 
Sbjct: 118 VDLFRAYDASLAMLM-RKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADL 176

Query: 183 EENVTIPRLLVKKYDALSIYSRLLDAHVYVMKHWILDYIVDSEKFTSIKGEVVPYIVKKQ 242
           +E + I   +++K+  +  ++ L+DAH+Y +K +I+D+++++   TSI+ E++PY+V+KQ
Sbjct: 177 DEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQ 236

Query: 243 LTKPNNLVEKKGTSEKNAEINKGIFDYAIETGY--ERKIREISAYNDHKHGNKGVYFND- 299
            +  ++   ++G  EK  ++ K          +  E     ++ Y+   +  +G  + D 
Sbjct: 237 FSSASS---QQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDL 293

Query: 300 ---TLRCYAHIPSKNTFAIRVNTLSSFYLSNNKILSKWQDLTGSSLFERFHPNSEVKTIQ 356
               +RCY HI  K     RV+TL  +  +N ++      L         H ++++ +  
Sbjct: 294 SRSQVRCYVHI-MKEGLCSRVSTLGLYMEANRQVPKLLSALCPEE--PPVHSSAQIVSKH 350

Query: 357 -IDDNCTVGEKTIINEKTSVKNSFIGSNCNIENKVRLTNCILMNNVTIKE 405
            +  +  +G +T I EK+S+K S IGS+C I+++V +TNC+LMN+VT++E
Sbjct: 351 LVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEE 400


>AL136380-5|CAI23131.1|  452|Homo sapiens eukaryotic translation
           initiation factor 2B, subunit 3 gamma, 58kDa protein.
          Length = 452

 Score =  252 bits (616), Expect = 3e-66
 Identities = 141/410 (34%), Positives = 247/410 (60%), Gaps = 19/410 (4%)

Query: 5   LEFQVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVLDEDK 64
           +EFQ VV+A G GSRM D+  S+ K LLPVG  P++WYPLN+LE++GF++V IVV   D 
Sbjct: 1   MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEV-IVVTTRDV 59

Query: 65  SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSARINTDLLVISGDLITNINLNDV 124
              L A  K  +K+K +++ IP + D GTA+SL+++  ++ TD+LV+S DLIT++ L++V
Sbjct: 60  QKALCAEFK--MKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEV 117

Query: 125 LNLHRKHDACVTTLFFNNGPEEWIELPGPKTKSKP--DRDLVCIDKETERLVFLASASDF 182
           ++L R +DA +  L    G +    +PG K K K    RD + +D   +RL+F+A+ +D 
Sbjct: 118 VDLFRAYDASLAMLM-RKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADL 176

Query: 183 EENVTIPRLLVKKYDALSIYSRLLDAHVYVMKHWILDYIVDSEKFTSIKGEVVPYIVKKQ 242
           +E + I   +++K+  +  ++ L+DAH+Y +K +I+D+++++   TSI+ E++PY+V+KQ
Sbjct: 177 DEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQ 236

Query: 243 LTKPNNLVEKKGTSEKNAEINKGIFDYAIETGY--ERKIREISAYNDHKHGNKGVYFND- 299
            +  ++   ++G  EK  ++ K          +  E     ++ Y+   +  +G  + D 
Sbjct: 237 FSSASS---QQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDL 293

Query: 300 ---TLRCYAHIPSKNTFAIRVNTLSSFYLSNNKILSKWQDLTGSSLFERFHPNSEVKTIQ 356
               +RCY HI  K     RV+TL  +  +N ++      L         H ++++ +  
Sbjct: 294 SRSQVRCYVHI-MKEGLCSRVSTLGLYMEANRQVPKLLSALCPEE--PPVHSSAQIVSKH 350

Query: 357 -IDDNCTVGEKTIINEKTSVKNSFIGSNCNIENKVRLTNCILMNNVTIKE 405
            +  +  +G +T I EK+S+K S IGS+C I+++V +TNC+LMN+VT++E
Sbjct: 351 LVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEE 400


>AF257077-1|AAF91351.1|  452|Homo sapiens eukaryotic translation
           initiation factor EIF2B subunit 3 protein.
          Length = 452

 Score =  252 bits (616), Expect = 3e-66
 Identities = 141/410 (34%), Positives = 247/410 (60%), Gaps = 19/410 (4%)

Query: 5   LEFQVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVLDEDK 64
           +EFQ VV+A G GSRM D+  S+ K LLPVG  P++WYPLN+LE++GF++V IVV   D 
Sbjct: 1   MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEV-IVVTTRDV 59

Query: 65  SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSARINTDLLVISGDLITNINLNDV 124
              L A  K  +K+K +++ IP + D GTA+SL+++  ++ TD+LV+S DLIT++ L++V
Sbjct: 60  QKALCAEFK--MKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEV 117

Query: 125 LNLHRKHDACVTTLFFNNGPEEWIELPGPKTKSKP--DRDLVCIDKETERLVFLASASDF 182
           ++L R +DA +  L    G +    +PG K K K    RD + +D   +RL+F+A+ +D 
Sbjct: 118 VDLFRAYDASLAMLM-RKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADL 176

Query: 183 EENVTIPRLLVKKYDALSIYSRLLDAHVYVMKHWILDYIVDSEKFTSIKGEVVPYIVKKQ 242
           +E + I   +++K+  +  ++ L+DAH+Y +K +I+D+++++   TSI+ E++PY+V+KQ
Sbjct: 177 DEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQ 236

Query: 243 LTKPNNLVEKKGTSEKNAEINKGIFDYAIETGY--ERKIREISAYNDHKHGNKGVYFND- 299
            +  ++   ++G  EK  ++ K          +  E     ++ Y+   +  +G  + D 
Sbjct: 237 FSSASS---QQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDL 293

Query: 300 ---TLRCYAHIPSKNTFAIRVNTLSSFYLSNNKILSKWQDLTGSSLFERFHPNSEVKTIQ 356
               +RCY HI  K     RV+TL  +  +N ++      L         H ++++ +  
Sbjct: 294 SRSQVRCYVHI-MKEGLCSRVSTLGLYMEANRQVPKLLSALCPEE--PPVHSSAQIVSKH 350

Query: 357 -IDDNCTVGEKTIINEKTSVKNSFIGSNCNIENKVRLTNCILMNNVTIKE 405
            +  +  +G +T I EK+S+K S IGS+C I+++V +TNC+LMN+VT++E
Sbjct: 351 LVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEE 400


>AK024006-1|BAB14770.1|  452|Homo sapiens NA.  protein.
          Length = 452

 Score =  251 bits (614), Expect = 4e-66
 Identities = 141/410 (34%), Positives = 247/410 (60%), Gaps = 19/410 (4%)

Query: 5   LEFQVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVLDEDK 64
           +EFQ VV+A G GSRM D+  S+ K LLPVG  P++WYPLN+LE++GF++V IVV   D 
Sbjct: 1   MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEV-IVVTTRDV 59

Query: 65  SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSARINTDLLVISGDLITNINLNDV 124
              L A  K  +K+K +++ IP + D GTA+SL+++  ++ TD+LV+S DLIT++ L++V
Sbjct: 60  QKALCAEFK--MKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEV 117

Query: 125 LNLHRKHDACVTTLFFNNGPEEWIELPGPKTKSKP--DRDLVCIDKETERLVFLASASDF 182
           ++L R +DA +  L    G +    +PG K K K    RD + +D   +RL+F+A+ +D 
Sbjct: 118 VDLFRAYDASLAMLM-RKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADL 176

Query: 183 EENVTIPRLLVKKYDALSIYSRLLDAHVYVMKHWILDYIVDSEKFTSIKGEVVPYIVKKQ 242
           +E + I   +++K+  +  ++ L+DAH+Y +K +I+D+++++   TSI+ E++PY+V+KQ
Sbjct: 177 DEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQ 236

Query: 243 LTKPNNLVEKKGTSEKNAEINKGIFDYAIETGY--ERKIREISAYNDHKHGNKGVYFND- 299
            +  ++   ++G  EK  ++ K          +  E     ++ Y+   +  +G  + D 
Sbjct: 237 FSSASS---QQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDL 293

Query: 300 ---TLRCYAHIPSKNTFAIRVNTLSSFYLSNNKILSKWQDLTGSSLFERFHPNSEVKTIQ 356
               +RCY HI  K     RV+TL  +  +N ++      L         H ++++ +  
Sbjct: 294 SRSQVRCYVHI-MKEGLCSRVSTLGLYMEANRQVPKLLSALCPEE--PPVHSSAQIVSKH 350

Query: 357 -IDDNCTVGEKTIINEKTSVKNSFIGSNCNIENKVRLTNCILMNNVTIKE 405
            +  +  +G +T I EK+S+K S IGS+C I+++V +TNC+LMN+VT++E
Sbjct: 351 LVGVDGLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEE 400


>AL136380-7|CAI23133.1|  197|Homo sapiens eukaryotic translation
           initiation factor 2B, subunit 3 gamma, 58kDa protein.
          Length = 197

 Score =  140 bits (339), Expect = 9e-33
 Identities = 72/161 (44%), Positives = 108/161 (67%), Gaps = 4/161 (2%)

Query: 5   LEFQVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVLDEDK 64
           +EFQ VV+A G GSRM D+  S+ K LLPVG  P++WYPLN+LE++GF++V IVV   D 
Sbjct: 1   MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEV-IVVTTRDV 59

Query: 65  SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSARINTDLLVISGDLITNINLNDV 124
              L A  K  +K+K +++ IP + D GTA+SL+++  ++ TD+LV+S DLIT++ L++V
Sbjct: 60  QKALCAEFK--MKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEV 117

Query: 125 LNLHRKHDACVTTLFFNNGPEEWIELPGPKTKSKPDRDLVC 165
           ++L R +DA +  L    G +    +PG K K K D D +C
Sbjct: 118 VDLFRAYDASLAML-MRKGQDSIEPVPGQKGKKKADGDSLC 157


>CR457285-1|CAG33566.1|  283|Homo sapiens EIF2B3 protein.
          Length = 283

 Score =  114 bits (274), Expect = 7e-25
 Identities = 66/237 (27%), Positives = 133/237 (56%), Gaps = 13/237 (5%)

Query: 176 LASASDFEENVTIPRLLVKKYDALSIYSRLLDAHVYVMKHWILDYIVDSEKFTSIKGEVV 235
           +A+ +D +E + I   +++K+  +  ++ L+DAH+Y +K +I+D+++++   TSI+ E++
Sbjct: 1   MANEADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELI 60

Query: 236 PYIVKKQLTKPNNLVEKKGTSEKNAEINKGIFDYAIETGY--ERKIREISAYNDHKHGNK 293
           PY+V+KQ +  ++   ++G  EK  ++ K          +  E     ++ Y+   +  +
Sbjct: 61  PYLVRKQFSSASS---QQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACR 117

Query: 294 GVYFND----TLRCYAHIPSKNTFAIRVNTLSSFYLSNNKILSKWQDLTGSSLFERFHPN 349
           G  + D     +RCY HI  K     RV+TL  +  +N ++      L         H +
Sbjct: 118 GDRWEDLSRSQVRCYVHI-MKEGLCSRVSTLGLYMEANRQVPKLLSALCPEE--PPVHSS 174

Query: 350 SEVKTIQ-IDDNCTVGEKTIINEKTSVKNSFIGSNCNIENKVRLTNCILMNNVTIKE 405
           +++ +   +  +  +G +T I EK+S+K S IGS+C I+++V +TNC+LMN+VT++E
Sbjct: 175 AQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEE 231


>AK022399-1|BAB14027.1|  283|Homo sapiens protein ( Homo sapiens
           cDNA FLJ12337 fis, clone MAMMA1002236, highly similar to
           TRANSLATION INITIATION FACTOR EIF-2B GAMMA SUBUNIT. ).
          Length = 283

 Score =  114 bits (274), Expect = 7e-25
 Identities = 66/237 (27%), Positives = 133/237 (56%), Gaps = 13/237 (5%)

Query: 176 LASASDFEENVTIPRLLVKKYDALSIYSRLLDAHVYVMKHWILDYIVDSEKFTSIKGEVV 235
           +A+ +D +E + I   +++K+  +  ++ L+DAH+Y +K +I+D+++++   TSI+ E++
Sbjct: 1   MANEADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELI 60

Query: 236 PYIVKKQLTKPNNLVEKKGTSEKNAEINKGIFDYAIETGY--ERKIREISAYNDHKHGNK 293
           PY+V+KQ +  ++   ++G  EK  ++ K          +  E     ++ Y+   +  +
Sbjct: 61  PYLVRKQFSSASS---QQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACR 117

Query: 294 GVYFND----TLRCYAHIPSKNTFAIRVNTLSSFYLSNNKILSKWQDLTGSSLFERFHPN 349
           G  + D     +RCY HI  K     RV+TL  +  +N ++      L         H +
Sbjct: 118 GDRWEDLSRSQVRCYVHI-MKEGLCSRVSTLGLYMEANRQVPKLLSALCPEE--PPVHSS 174

Query: 350 SEVKTIQ-IDDNCTVGEKTIINEKTSVKNSFIGSNCNIENKVRLTNCILMNNVTIKE 405
           +++ +   +  +  +G +T I EK+S+K S IGS+C I+++V +TNC+LMN+VT++E
Sbjct: 175 AQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEE 231


>AL136380-3|CAI23129.1|  221|Homo sapiens eukaryotic translation
           initiation factor 2B, subunit 3 gamma, 58kDa protein.
          Length = 221

 Score =  106 bits (254), Expect = 2e-22
 Identities = 62/221 (28%), Positives = 124/221 (56%), Gaps = 13/221 (5%)

Query: 192 LVKKYDALSIYSRLLDAHVYVMKHWILDYIVDSEKFTSIKGEVVPYIVKKQLTKPNNLVE 251
           +++K+  +  ++ L+DAH+Y +K +I+D+++++   TSI+ E++PY+V+KQ +  ++   
Sbjct: 6   ILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSASS--- 62

Query: 252 KKGTSEKNAEINKGIFDYAIETGY--ERKIREISAYNDHKHGNKGVYFNDT----LRCYA 305
           ++G  EK  ++ K          +  E     ++ Y+   +  +G  + D     +RCY 
Sbjct: 63  QQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRCYV 122

Query: 306 HIPSKNTFAIRVNTLSSFYLSNNKILSKWQDLTGSSLFERFHPNSEVKTIQ-IDDNCTVG 364
           HI  K     RV+TL  +  +N ++      L         H ++++ +   +  +  +G
Sbjct: 123 HI-MKEGLCSRVSTLGLYMEANRQVPKLLSALCPEE--PPVHSSAQIVSKHLVGVDSLIG 179

Query: 365 EKTIINEKTSVKNSFIGSNCNIENKVRLTNCILMNNVTIKE 405
            +T I EK+S+K S IGS+C I+++V +TNC+LMN+VT++E
Sbjct: 180 PETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEE 220


>BC013590-1|AAH13590.1|  721|Homo sapiens eukaryotic translation
           initiation factor 2B, subunit 5 epsilon, 82kDa protein.
          Length = 721

 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 49/227 (21%), Positives = 89/227 (39%), Gaps = 17/227 (7%)

Query: 8   QVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVL---DEDK 64
           Q V++A     R   +     + LLP+    ++ Y L  L   G Q+  +       + K
Sbjct: 44  QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIK 103

Query: 65  SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSAR--INTDLLVISGDLITNINLN 122
            ++L +    P  +   + +I SE      + L+ V A+  + +D L++ GD+I+NIN+ 
Sbjct: 104 EHLLKSKWCRPTSLNV-VRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINIT 162

Query: 123 DVLNLHR-----KHDACVTTLFFNNGPEEWIELPGPKTKSKPDRDLVCIDKETERLVFLA 177
             L  HR     + +  V T+ F          P   T+   D  +V +D  T R++   
Sbjct: 163 RALEEHRLRRKLEKNVSVMTMIFKESS------PSHPTRCHEDNVVVAVDSTTNRVLHFQ 216

Query: 178 SASDFEENVTIPRLLVKKYDALSIYSRLLDAHVYVMKHWILDYIVDS 224
                        L     D + +   LLD H+ +    +     D+
Sbjct: 217 KTQGLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDN 263



 Score = 32.3 bits (70), Expect = 3.6
 Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 6/98 (6%)

Query: 357 IDDNCTVGEKTIINEKTSVKNSFIGSNCNIENKVRLTNCILMNNVTIKESLAQL--TMTP 414
           +++N  +G  T+I     + NS IG  C+I + V L    L   V +    AQ+  ++  
Sbjct: 356 LEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAG-AQIHQSLLC 414

Query: 415 KDCRVKFAAGVSPIEEYYKEITI---LSIEEKNASSLH 449
            +  VK    + P      ++ +   +++ E +  SLH
Sbjct: 415 DNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLH 452


>AK091646-1|BAC03712.1|  721|Homo sapiens protein ( Homo sapiens
           cDNA FLJ34327 fis, clone FEBRA2009022, highly similar to
           TRANSLATION INITIATION FACTOR EIF-2B EPSILON SUBUNIT. ).
          Length = 721

 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 49/227 (21%), Positives = 89/227 (39%), Gaps = 17/227 (7%)

Query: 8   QVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVL---DEDK 64
           Q V++A     R   +     + LLP+    ++ Y L  L   G Q+  +       + K
Sbjct: 44  QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIK 103

Query: 65  SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSAR--INTDLLVISGDLITNINLN 122
            ++L +    P  +   + +I SE      + L+ V A+  + +D L++ GD+I+NIN+ 
Sbjct: 104 EHLLKSKWCRPTSLNV-VRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINIT 162

Query: 123 DVLNLHR-----KHDACVTTLFFNNGPEEWIELPGPKTKSKPDRDLVCIDKETERLVFLA 177
             L  HR     + +  V T+ F          P   T+   D  +V +D  T R++   
Sbjct: 163 RALEEHRLRRKLEKNVSVMTMIFKESS------PSHPTRCHEDNVVVAVDSTTNRVLHFQ 216

Query: 178 SASDFEENVTIPRLLVKKYDALSIYSRLLDAHVYVMKHWILDYIVDS 224
                        L     D + +   LLD H+ +    +     D+
Sbjct: 217 KTQGLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDN 263



 Score = 32.3 bits (70), Expect = 3.6
 Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 6/98 (6%)

Query: 357 IDDNCTVGEKTIINEKTSVKNSFIGSNCNIENKVRLTNCILMNNVTIKESLAQL--TMTP 414
           +++N  +G  T+I     + NS IG  C+I + V L    L   V +    AQ+  ++  
Sbjct: 356 LEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAG-AQIHQSLLC 414

Query: 415 KDCRVKFAAGVSPIEEYYKEITI---LSIEEKNASSLH 449
            +  VK    + P      ++ +   +++ E +  SLH
Sbjct: 415 DNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLH 452


>U23028-1|AAC50646.1|  641|Homo sapiens eIF-2Bepsilon protein.
          Length = 641

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 34/148 (22%), Positives = 59/148 (39%), Gaps = 13/148 (8%)

Query: 84  VIPSEEDWGTANSLKHVSAR--INTDLLVISGDLITNINLNDVLNLHR-----KHDACVT 136
           +I SE      + L+ V A+  + +D L++ GD+I+NIN+   L  HR     + +  V 
Sbjct: 42  IITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSVM 101

Query: 137 TLFFNNGPEEWIELPGPKTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKY 196
           T+ F          P   T+   D  +V +D  T R++                L     
Sbjct: 102 TMIFKESS------PSHPTRCHEDNVVVAVDSTTNRVLHFQKTQGLRRFAFPLSLFQGSS 155

Query: 197 DALSIYSRLLDAHVYVMKHWILDYIVDS 224
           D + +   LLD H+ +    +     D+
Sbjct: 156 DGVEVRYDLLDCHISICSPQVAQLFTDN 183



 Score = 32.3 bits (70), Expect = 3.6
 Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 6/98 (6%)

Query: 357 IDDNCTVGEKTIINEKTSVKNSFIGSNCNIENKVRLTNCILMNNVTIKESLAQL--TMTP 414
           +++N  +G  T+I     + NS IG  C+I + V L    L   V +    AQ+  ++  
Sbjct: 276 LEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAG-AQIHQSLLC 334

Query: 415 KDCRVKFAAGVSPIEEYYKEITI---LSIEEKNASSLH 449
            +  VK    + P      ++ +   +++ E +  SLH
Sbjct: 335 DNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLH 372


>AK222951-1|BAD96671.1|  420|Homo sapiens GDP-mannose
           pyrophosphorylase A variant protein.
          Length = 420

 Score = 36.3 bits (80), Expect = 0.22
 Identities = 27/130 (20%), Positives = 56/130 (43%), Gaps = 7/130 (5%)

Query: 8   QVVVLAAG--KGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKI-GFQDVMIVVLDEDK 64
           + V+L  G  KG+R   +   V K L PV   P++ + +    ++ G Q+++++   +  
Sbjct: 3   KAVILIGGPQKGTRFRPLSFEVPKPLFPVAGVPMIQHHIEACAQVPGMQEILLICFYQPD 62

Query: 65  SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSARINTD----LLVISGDLITNIN 120
             +   LE    +    +  +      GT   L H   +I         V++ D+ ++  
Sbjct: 63  EPLTQFLEAAQQEFNLPVRYLQEFAPLGTGGGLYHFRDQILAGSPEAFFVLNADVCSDFP 122

Query: 121 LNDVLNLHRK 130
           L+ +L  HR+
Sbjct: 123 LSAMLEAHRR 132


>BC007456-1|AAH07456.1|  420|Homo sapiens GDP-mannose
           pyrophosphorylase A protein.
          Length = 420

 Score = 35.5 bits (78), Expect = 0.39
 Identities = 27/130 (20%), Positives = 56/130 (43%), Gaps = 7/130 (5%)

Query: 8   QVVVLAAG--KGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKI-GFQDVMIVVLDEDK 64
           + V+L  G  KG+R   +   V K L PV   P++ + +    ++ G Q+++++   +  
Sbjct: 3   KAVILIGGPQKGTRFRPLSFEVPKPLFPVAGVPMIQHHIEACAQVPGMQEILLIGFYQPD 62

Query: 65  SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSARINTD----LLVISGDLITNIN 120
             +   LE    +    +  +      GT   L H   +I         V++ D+ ++  
Sbjct: 63  EPLTQFLEAAQQEFNLPVRYLQEFAPLGTGGGLYHFRDQILAGSPEAFFVLNADVCSDFP 122

Query: 121 LNDVLNLHRK 130
           L+ +L  HR+
Sbjct: 123 LSAMLEAHRR 132


>AK000999-1|BAA91460.1|  420|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10137 fis, clone HEMBA1003136, weakly similar to
           MANNOSE-1-PHOSPHATE GUANYLTRANSFERASE (EC 2.7.7.13). ).
          Length = 420

 Score = 35.5 bits (78), Expect = 0.39
 Identities = 27/130 (20%), Positives = 56/130 (43%), Gaps = 7/130 (5%)

Query: 8   QVVVLAAG--KGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKI-GFQDVMIVVLDEDK 64
           + V+L  G  KG+R   +   V K L PV   P++ + +    ++ G Q+++++   +  
Sbjct: 3   KAVILIGGPQKGTRFRPLSFEVPKPLFPVAGVPMIQHHIEACAQVPGMQEILLIGFYQPD 62

Query: 65  SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSARINTD----LLVISGDLITNIN 120
             +   LE    +    +  +      GT   L H   +I         V++ D+ ++  
Sbjct: 63  EPLTQFLEAAQQEFNLPVRYLQEFAPLGTGGGLYHFRDQILAGSPEAFFVLNADVYSDFP 122

Query: 121 LNDVLNLHRK 130
           L+ +L  HR+
Sbjct: 123 LSAMLEAHRR 132


>AF135422-1|AAD38517.1|  399|Homo sapiens GDP-mannose
           pyrophosphorylase A protein.
          Length = 399

 Score = 35.5 bits (78), Expect = 0.39
 Identities = 27/130 (20%), Positives = 56/130 (43%), Gaps = 7/130 (5%)

Query: 8   QVVVLAAG--KGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKI-GFQDVMIVVLDEDK 64
           + V+L  G  KG+R   +   V K L PV   P++ + +    ++ G Q+++++   +  
Sbjct: 3   KAVILIGGPQKGTRFRPLSFEVPKPLFPVAGVPMIQHHIEACAQVPGMQEILLIGFYQPD 62

Query: 65  SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSARINTD----LLVISGDLITNIN 120
             +   LE    +    +  +      GT   L H   +I         V++ D+ ++  
Sbjct: 63  EPLTQFLEAAQQEFNLPVRYLQEFAPLGTGGGLYHFRDQILAGSPEAFFVLNADVCSDFP 122

Query: 121 LNDVLNLHRK 130
           L+ +L  HR+
Sbjct: 123 LSAMLEAHRR 132


>AC053503-4|AAY15053.1|  420|Homo sapiens unknown protein.
          Length = 420

 Score = 35.5 bits (78), Expect = 0.39
 Identities = 27/130 (20%), Positives = 56/130 (43%), Gaps = 7/130 (5%)

Query: 8   QVVVLAAG--KGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKI-GFQDVMIVVLDEDK 64
           + V+L  G  KG+R   +   V K L PV   P++ + +    ++ G Q+++++   +  
Sbjct: 3   KAVILIGGPQKGTRFRPLSFEVPKPLFPVAGVPMIQHHIEACAQVPGMQEILLIGFYQPD 62

Query: 65  SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSARINTD----LLVISGDLITNIN 120
             +   LE    +    +  +      GT   L H   +I         V++ D+ ++  
Sbjct: 63  EPLTQFLEAAQQEFNLPVRYLQEFAPLGTGGGLYHFRDQILAGSPEAFFVLNADVCSDFP 122

Query: 121 LNDVLNLHRK 130
           L+ +L  HR+
Sbjct: 123 LSAMLEAHRR 132


>BC112897-1|AAI12898.1|  906|Homo sapiens KIAA0350 protein protein.
          Length = 906

 Score = 32.7 bits (71), Expect = 2.7
 Identities = 28/126 (22%), Positives = 51/126 (40%), Gaps = 2/126 (1%)

Query: 285 YNDHKHGNKGVYFNDTLRCYAHIPSKNTFAIRVNTLSSFYLSNNKILSKWQDLTGSSLFE 344
           YN+H   N    + + ++ + H  S    A+R  TL+ + + N  +L   +D T    F 
Sbjct: 162 YNEHT--NDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVDNQAMLHYIRDKTAVPYFS 219

Query: 345 RFHPNSEVKTIQIDDNCTVGEKTIINEKTSVKNSFIGSNCNIENKVRLTNCILMNNVTIK 404
                     I++DD     E+     K S   +    + +  N + + NC  +N+V   
Sbjct: 220 NLVWFIGSHVIELDDCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTD 279

Query: 405 ESLAQL 410
             L +L
Sbjct: 280 HLLNRL 285


>AB232668-1|BAF51560.1| 1543|Homo sapiens YY1AP-related protein3
            protein.
          Length = 1543

 Score = 32.7 bits (71), Expect = 2.7
 Identities = 24/89 (26%), Positives = 46/89 (51%), Gaps = 5/89 (5%)

Query: 143  GPEEWIELPGPKTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSIY 202
            GPE   E  GP+ + + D D +  D+E E    ++SAS+ E  +++P L V+  +   ++
Sbjct: 1447 GPETGGEKNGPEEEEEEDFDDLTQDEEDE----MSSASE-ESVLSVPELQVRAGEYSQVF 1501

Query: 203  SRLLDAHVYVMKHWILDYIVDSEKFTSIK 231
              L + +  ++ H +    +DS K   I+
Sbjct: 1502 RGLSNMYHLLICHLLACCTMDSPKIICIR 1530


>BC036756-1|AAH36756.1|  377|Homo sapiens guanine nucleotide binding
           protein (G protein), alpha 13 protein.
          Length = 377

 Score = 32.3 bits (70), Expect = 3.6
 Identities = 18/70 (25%), Positives = 41/70 (58%), Gaps = 3/70 (4%)

Query: 142 NGPEEWIELPGPKTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSI 201
           N P + +++ G +++ K  R   C D  T  ++FL S+S+F++ +   RL  +  ++L+I
Sbjct: 215 NVPFKMVDVGGQRSERK--RWFECFDSVTS-ILFLVSSSEFDQVLMEDRLTNRLTESLNI 271

Query: 202 YSRLLDAHVY 211
           +  +++  V+
Sbjct: 272 FETIVNNRVF 281


>AF493902-1|AAM12616.1|  377|Homo sapiens guanine nucleotide binding
           protein alpha 13 protein.
          Length = 377

 Score = 32.3 bits (70), Expect = 3.6
 Identities = 18/70 (25%), Positives = 41/70 (58%), Gaps = 3/70 (4%)

Query: 142 NGPEEWIELPGPKTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSI 201
           N P + +++ G +++ K  R   C D  T  ++FL S+S+F++ +   RL  +  ++L+I
Sbjct: 215 NVPFKMVDVGGQRSERK--RWFECFDSVTS-ILFLVSSSEFDQVLMEDRLTNRLTESLNI 271

Query: 202 YSRLLDAHVY 211
           +  +++  V+
Sbjct: 272 FETIVNNRVF 281


>AB208821-1|BAD92058.1|  338|Homo sapiens eukaryotic translation
           initiation factor 2B, subunit 5 epsilon, 82kDa variant
           protein.
          Length = 338

 Score = 32.3 bits (70), Expect = 3.6
 Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 6/98 (6%)

Query: 357 IDDNCTVGEKTIINEKTSVKNSFIGSNCNIENKVRLTNCILMNNVTIKESLAQL--TMTP 414
           +++N  +G  T+I     + NS IG  C+I + V L    L   V +    AQ+  ++  
Sbjct: 112 LEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAG-AQIHQSLLC 170

Query: 415 KDCRVKFAAGVSPIEEYYKEITI---LSIEEKNASSLH 449
            +  VK    + P      ++ +   +++ E +  SLH
Sbjct: 171 DNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLH 208


>L22075-1|AAA74235.1|  377|Homo sapiens guanine nucleotide
           regulatory protein protein.
          Length = 377

 Score = 31.9 bits (69), Expect = 4.8
 Identities = 18/70 (25%), Positives = 41/70 (58%), Gaps = 3/70 (4%)

Query: 142 NGPEEWIELPGPKTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSI 201
           N P + +++ G +++ K  R   C D  T  ++FL S+S+F++ +   RL  +  ++L+I
Sbjct: 215 NVPFKMLDVGGQRSERK--RWFECFDSVTS-ILFLVSSSEFDQVLMEDRLTNRLTESLNI 271

Query: 202 YSRLLDAHVY 211
           +  +++  V+
Sbjct: 272 FETIVNNRVF 281


>BX537764-1|CAD97829.1| 1546|Homo sapiens hypothetical protein
            protein.
          Length = 1546

 Score = 31.9 bits (69), Expect = 4.8
 Identities = 24/88 (27%), Positives = 45/88 (51%), Gaps = 5/88 (5%)

Query: 143  GPEEWIELPGPKTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSIY 202
            GPE   E  GP+ + + D D +  D+E E    ++SAS+ E  +++P L V+  +   ++
Sbjct: 1464 GPETGGEKNGPEEEEEEDFDDLTQDEEDE----MSSASE-ESVLSVPELQVRAGEYSQVF 1518

Query: 203  SRLLDAHVYVMKHWILDYIVDSEKFTSI 230
              L + +  ++ H +    +DS K   I
Sbjct: 1519 RGLSNMYHLLICHLLACCTMDSPKIICI 1546


>BC115703-1|AAI15704.1| 1529|Homo sapiens gon-4-like (C. elegans)
            protein.
          Length = 1529

 Score = 31.9 bits (69), Expect = 4.8
 Identities = 24/88 (27%), Positives = 45/88 (51%), Gaps = 5/88 (5%)

Query: 143  GPEEWIELPGPKTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSIY 202
            GPE   E  GP+ + + D D +  D+E E    ++SAS+ E  +++P L V+  +   ++
Sbjct: 1447 GPETGGEKNGPEEEEEEDFDDLTQDEEDE----MSSASE-ESVLSVPELQVRAGEYSQVF 1501

Query: 203  SRLLDAHVYVMKHWILDYIVDSEKFTSI 230
              L + +  ++ H +    +DS K   I
Sbjct: 1502 RGLSNMYHLLICHLLACCTMDSPKIICI 1529


>BC114629-1|AAI14630.1| 1529|Homo sapiens gon-4-like (C. elegans)
            protein.
          Length = 1529

 Score = 31.9 bits (69), Expect = 4.8
 Identities = 24/88 (27%), Positives = 45/88 (51%), Gaps = 5/88 (5%)

Query: 143  GPEEWIELPGPKTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSIY 202
            GPE   E  GP+ + + D D +  D+E E    ++SAS+ E  +++P L V+  +   ++
Sbjct: 1447 GPETGGEKNGPEEEEEEDFDDLTQDEEDE----MSSASE-ESVLSVPELQVRAGEYSQVF 1501

Query: 203  SRLLDAHVYVMKHWILDYIVDSEKFTSI 230
              L + +  ++ H +    +DS K   I
Sbjct: 1502 RGLSNMYHLLICHLLACCTMDSPKIICI 1529


>BC036740-1|AAH36740.2|  981|Homo sapiens GON4L protein protein.
          Length = 981

 Score = 31.9 bits (69), Expect = 4.8
 Identities = 24/88 (27%), Positives = 45/88 (51%), Gaps = 5/88 (5%)

Query: 143 GPEEWIELPGPKTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSIY 202
           GPE   E  GP+ + + D D +  D+E E    ++SAS+ E  +++P L V+  +   ++
Sbjct: 899 GPETGGEKNGPEEEEEEDFDDLTQDEEDE----MSSASE-ESVLSVPELQVRAGEYSQVF 953

Query: 203 SRLLDAHVYVMKHWILDYIVDSEKFTSI 230
             L + +  ++ H +    +DS K   I
Sbjct: 954 RGLSNMYHLLICHLLACCTMDSPKIICI 981


>AY335492-1|AAR01262.1| 1529|Homo sapiens GON4L isoform B protein.
          Length = 1529

 Score = 31.9 bits (69), Expect = 4.8
 Identities = 24/88 (27%), Positives = 45/88 (51%), Gaps = 5/88 (5%)

Query: 143  GPEEWIELPGPKTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSIY 202
            GPE   E  GP+ + + D D +  D+E E    ++SAS+ E  +++P L V+  +   ++
Sbjct: 1447 GPETGGEKNGPEEEEEEDFDDLTQDEEDE----MSSASE-ESVLSVPELQVRAGEYSQVF 1501

Query: 203  SRLLDAHVYVMKHWILDYIVDSEKFTSI 230
              L + +  ++ H +    +DS K   I
Sbjct: 1502 RGLSNMYHLLICHLLACCTMDSPKIICI 1529


>AL139128-5|CAH69947.1| 1529|Homo sapiens novel protein protein.
          Length = 1529

 Score = 31.9 bits (69), Expect = 4.8
 Identities = 24/88 (27%), Positives = 45/88 (51%), Gaps = 5/88 (5%)

Query: 143  GPEEWIELPGPKTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSIY 202
            GPE   E  GP+ + + D D +  D+E E    ++SAS+ E  +++P L V+  +   ++
Sbjct: 1447 GPETGGEKNGPEEEEEEDFDDLTQDEEDE----MSSASE-ESVLSVPELQVRAGEYSQVF 1501

Query: 203  SRLLDAHVYVMKHWILDYIVDSEKFTSI 230
              L + +  ++ H +    +DS K   I
Sbjct: 1502 RGLSNMYHLLICHLLACCTMDSPKIICI 1529


>AK222851-1|BAD96571.1|  852|Homo sapiens Hypothetical protein
           DKFZp761I241 (Fragment) variant protein.
          Length = 852

 Score = 31.9 bits (69), Expect = 4.8
 Identities = 24/88 (27%), Positives = 45/88 (51%), Gaps = 5/88 (5%)

Query: 143 GPEEWIELPGPKTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSIY 202
           GPE   E  GP+ + + D D +  D+E E    ++SAS+ E  +++P L V+  +   ++
Sbjct: 770 GPETGGEKNGPEEEEEEDFDDLTQDEEDE----MSSASE-ESVLSVPELQVRAGEYSQVF 824

Query: 203 SRLLDAHVYVMKHWILDYIVDSEKFTSI 230
             L + +  ++ H +    +DS K   I
Sbjct: 825 RGLSNMYHLLICHLLACCTMDSPKIICI 852


>AK022985-1|BAB14347.1|  725|Homo sapiens protein ( Homo sapiens
           cDNA FLJ12923 fis, clone NT2RP2004681, weakly similar to
           NEUROFILAMENT TRIPLET H PROTEIN. ).
          Length = 725

 Score = 31.9 bits (69), Expect = 4.8
 Identities = 24/88 (27%), Positives = 45/88 (51%), Gaps = 5/88 (5%)

Query: 143 GPEEWIELPGPKTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSIY 202
           GPE   E  GP+ + + D D +  D+E E    ++SAS+ E  +++P L V+  +   ++
Sbjct: 643 GPETGGEKNGPEEEEEEDFDDLTQDEEDE----MSSASE-ESVLSVPELQVRAGEYSQVF 697

Query: 203 SRLLDAHVYVMKHWILDYIVDSEKFTSI 230
             L + +  ++ H +    +DS K   I
Sbjct: 698 RGLSNMYHLLICHLLACCTMDSPKIICI 725


>BX537849-1|CAD97857.1| 1626|Homo sapiens hypothetical protein
           protein.
          Length = 1626

 Score = 31.5 bits (68), Expect = 6.3
 Identities = 15/52 (28%), Positives = 26/52 (50%)

Query: 154 KTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSIYSRL 205
           K +   D +L  +D   E  +F  +  DFE  + +P L + KY  L ++ R+
Sbjct: 78  KAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKYPYLLLHERV 129


>BC008033-1|AAH08033.1|  360|Homo sapiens GDP-mannose
           pyrophosphorylase B protein.
          Length = 360

 Score = 31.5 bits (68), Expect = 6.3
 Identities = 28/128 (21%), Positives = 54/128 (42%), Gaps = 6/128 (4%)

Query: 8   QVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVLDEDKSNI 67
           + ++L  G G+R+  +  S  K L+     P+L + +  L   G   V++ V     S +
Sbjct: 2   KALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAV--SYMSQV 59

Query: 68  LNALEKC-PLKIKYELIVIPSEEDWGTANSL---KHVSARINTDLLVISGDLITNINLND 123
           L    K    ++   + +   EE  GTA  L   + + +       V++ D+I +     
Sbjct: 60  LEKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSDVICDFPFQA 119

Query: 124 VLNLHRKH 131
           ++  HR H
Sbjct: 120 MVQFHRHH 127


>BC001141-1|AAH01141.1|  360|Homo sapiens GDP-mannose
           pyrophosphorylase B protein.
          Length = 360

 Score = 31.5 bits (68), Expect = 6.3
 Identities = 28/128 (21%), Positives = 54/128 (42%), Gaps = 6/128 (4%)

Query: 8   QVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVLDEDKSNI 67
           + ++L  G G+R+  +  S  K L+     P+L + +  L   G   V++ V     S +
Sbjct: 2   KALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAV--SYMSQV 59

Query: 68  LNALEKC-PLKIKYELIVIPSEEDWGTANSL---KHVSARINTDLLVISGDLITNINLND 123
           L    K    ++   + +   EE  GTA  L   + + +       V++ D+I +     
Sbjct: 60  LEKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSDVICDFPFQA 119

Query: 124 VLNLHRKH 131
           ++  HR H
Sbjct: 120 MVQFHRHH 127


>AY362728-1|AAR13367.1| 2677|Homo sapiens ataxia/oculomotor apraxia
           protein 2 protein.
          Length = 2677

 Score = 31.5 bits (68), Expect = 6.3
 Identities = 15/52 (28%), Positives = 26/52 (50%)

Query: 154 KTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSIYSRL 205
           K +   D +L  +D   E  +F  +  DFE  + +P L + KY  L ++ R+
Sbjct: 78  KAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKYPYLLLHERV 129


>AL353701-2|CAM14151.1| 2677|Homo sapiens senataxin protein.
          Length = 2677

 Score = 31.5 bits (68), Expect = 6.3
 Identities = 15/52 (28%), Positives = 26/52 (50%)

Query: 154 KTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSIYSRL 205
           K +   D +L  +D   E  +F  +  DFE  + +P L + KY  L ++ R+
Sbjct: 78  KAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKYPYLLLHERV 129


>AL353701-1|CAM14150.1|  670|Homo sapiens senataxin protein.
          Length = 670

 Score = 31.5 bits (68), Expect = 6.3
 Identities = 15/52 (28%), Positives = 26/52 (50%)

Query: 154 KTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSIYSRL 205
           K +   D +L  +D   E  +F  +  DFE  + +P L + KY  L ++ R+
Sbjct: 78  KAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKYPYLLLHERV 129


>AL159997-2|CAI40854.1| 2677|Homo sapiens senataxin protein.
          Length = 2677

 Score = 31.5 bits (68), Expect = 6.3
 Identities = 15/52 (28%), Positives = 26/52 (50%)

Query: 154 KTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSIYSRL 205
           K +   D +L  +D   E  +F  +  DFE  + +P L + KY  L ++ R+
Sbjct: 78  KAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKYPYLLLHERV 129


>AL159997-1|CAI40858.2|  670|Homo sapiens senataxin protein.
          Length = 670

 Score = 31.5 bits (68), Expect = 6.3
 Identities = 15/52 (28%), Positives = 26/52 (50%)

Query: 154 KTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSIYSRL 205
           K +   D +L  +D   E  +F  +  DFE  + +P L + KY  L ++ R+
Sbjct: 78  KAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKYPYLLLHERV 129


>AK125448-1|BAC86166.1|  635|Homo sapiens protein ( Homo sapiens
           cDNA FLJ43459 fis, clone OCBBF2035564. ).
          Length = 635

 Score = 31.5 bits (68), Expect = 6.3
 Identities = 15/52 (28%), Positives = 26/52 (50%)

Query: 154 KTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSIYSRL 205
           K +   D +L  +D   E  +F  +  DFE  + +P L + KY  L ++ R+
Sbjct: 78  KAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKYPYLLLHERV 129


>AK024319-1|BAB14882.1|  387|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14257 fis, clone PLACE1000547, highly similar to
           Homo sapiens GDP-mannose pyrophosphorylase B (GMPPB)
           mRNA. ).
          Length = 387

 Score = 31.5 bits (68), Expect = 6.3
 Identities = 28/128 (21%), Positives = 54/128 (42%), Gaps = 6/128 (4%)

Query: 8   QVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVLDEDKSNI 67
           + ++L  G G+R+  +  S  K L+     P+L + +  L   G   V++ V     S +
Sbjct: 2   KALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAV--SYMSQV 59

Query: 68  LNALEKC-PLKIKYELIVIPSEEDWGTANSL---KHVSARINTDLLVISGDLITNINLND 123
           L    K    ++   + +   EE  GTA  L   + + +       V++ D+I +     
Sbjct: 60  LEKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSDVICDFPFQA 119

Query: 124 VLNLHRKH 131
           ++  HR H
Sbjct: 120 MVQFHRHH 127


>AF135421-1|AAD38516.1|  360|Homo sapiens GDP-mannose
           pyrophosphorylase B protein.
          Length = 360

 Score = 31.5 bits (68), Expect = 6.3
 Identities = 28/128 (21%), Positives = 54/128 (42%), Gaps = 6/128 (4%)

Query: 8   QVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVLDEDKSNI 67
           + ++L  G G+R+  +  S  K L+     P+L + +  L   G   V++ V     S +
Sbjct: 2   KALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAV--SYMSQV 59

Query: 68  LNALEKC-PLKIKYELIVIPSEEDWGTANSL---KHVSARINTDLLVISGDLITNINLND 123
           L    K    ++   + +   EE  GTA  L   + + +       V++ D+I +     
Sbjct: 60  LEKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSDVICDFPFQA 119

Query: 124 VLNLHRKH 131
           ++  HR H
Sbjct: 120 MVQFHRHH 127


>AB014525-1|BAA31600.2| 2663|Homo sapiens KIAA0625 protein protein.
          Length = 2663

 Score = 31.5 bits (68), Expect = 6.3
 Identities = 15/52 (28%), Positives = 26/52 (50%)

Query: 154 KTKSKPDRDLVCIDKETERLVFLASASDFEENVTIPRLLVKKYDALSIYSRL 205
           K +   D +L  +D   E  +F  +  DFE  + +P L + KY  L ++ R+
Sbjct: 64  KAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKYPYLLLHERV 115


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.317    0.135    0.393 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 64,994,903
Number of Sequences: 224733
Number of extensions: 2734184
Number of successful extensions: 4764
Number of sequences better than 10.0: 43
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 4692
Number of HSP's gapped (non-prelim): 70
length of query: 451
length of database: 73,234,838
effective HSP length: 92
effective length of query: 359
effective length of database: 52,559,402
effective search space: 18868825318
effective search space used: 18868825318
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 67 (31.1 bits)

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