Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000292-TA|BGIBMGA000292-PA|IPR013027|FAD-dependent
pyridine nucleotide-disulphide oxidoreductase,
IPR006258|Dihydrolipoamide dehydrogenase, IPR012999|Pyridine
nucleotide-disulphide oxidoreductase, class I, active site,
IPR001327|Pyridine nucleotide-disulphide oxidoreductase, NAD-binding
region, IPR000815|Mercuric reductase, IPR004099|Pyridine
nucleotide-disulphide oxidoreductase dimerisation region,
IPR001100|Pyridine nucleotide-disulphide oxidoreductase, class I
(496 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P09622 Cluster: Dihydrolipoyl dehydrogenase, mitochondr... 664 0.0
UniRef50_A0LAA4 Cluster: Dihydrolipoyl dehydrogenase; n=9; cellu... 545 e-153
UniRef50_Q67B06 Cluster: Dihydrolipoyl dehydrogenase; n=22; Bact... 520 e-146
UniRef50_Q1KSF4 Cluster: Dihydrolipoyl dehydrogenase; n=25; cell... 492 e-138
UniRef50_Q8F6S8 Cluster: Dihydrolipoyl dehydrogenase; n=30; Bact... 467 e-130
UniRef50_Q5FGZ4 Cluster: Dihydrolipoyl dehydrogenase; n=11; Rick... 456 e-127
UniRef50_P52992 Cluster: Dihydrolipoyl dehydrogenase; n=34; root... 452 e-125
UniRef50_P14218 Cluster: Dihydrolipoyl dehydrogenase; n=65; cell... 440 e-122
UniRef50_Q11NC9 Cluster: Dihydrolipoyl dehydrogenase; n=4; Alpha... 436 e-121
UniRef50_Q74AD0 Cluster: Dihydrolipoyl dehydrogenase; n=17; Prot... 428 e-118
UniRef50_Q7UVC8 Cluster: Dihydrolipoyl dehydrogenase; n=3; Bacte... 421 e-116
UniRef50_Q6MC87 Cluster: Dihydrolipoyl dehydrogenase; n=1; Candi... 413 e-114
UniRef50_Q4N0C2 Cluster: Dihydrolipoyl dehydrogenase; n=2; Theil... 395 e-108
UniRef50_P21880 Cluster: Dihydrolipoyl dehydrogenase; n=27; Baci... 386 e-106
UniRef50_Q6MPR7 Cluster: Dihydrolipoyl dehydrogenase; n=2; Delta... 382 e-104
UniRef50_Q9RRW5 Cluster: Dihydrolipoyl dehydrogenase; n=4; Deino... 380 e-104
UniRef50_P0A0E8 Cluster: Dihydrolipoyl dehydrogenase; n=46; Baci... 379 e-104
UniRef50_Q2RHM5 Cluster: Dihydrolipoyl dehydrogenase; n=4; Clost... 369 e-101
UniRef50_A7HBV5 Cluster: Dihydrolipoamide dehydrogenase; n=2; An... 368 e-100
UniRef50_Q892P7 Cluster: Dihydrolipoamide dehydrogenase; n=3; Cl... 365 2e-99
UniRef50_Q1R3M3 Cluster: Dihydrolipoyl dehydrogenase; n=4; Esche... 364 3e-99
UniRef50_Q3ETT1 Cluster: Dihydrolipoyl dehydrogenase; n=1; Bacil... 363 6e-99
UniRef50_Q13KM1 Cluster: Putative dihydrolipoamide dehydrogenase... 363 6e-99
UniRef50_A2F0F6 Cluster: Dihydrolipoyl dehydrogenase; n=2; Trich... 361 3e-98
UniRef50_A6C4P3 Cluster: Dihydrolipoyl dehydrogenase; n=1; Planc... 358 2e-97
UniRef50_P0A9P3 Cluster: Dihydrolipoyl dehydrogenase; n=182; Bac... 353 5e-96
UniRef50_Q1IIJ6 Cluster: Dihydrolipoyl dehydrogenase; n=4; Bacte... 353 6e-96
UniRef50_A5UXL4 Cluster: Dihydrolipoamide dehydrogenase; n=3; Ch... 353 6e-96
UniRef50_Q1IMV9 Cluster: Dihydrolipoyl dehydrogenase; n=2; Bacte... 351 2e-95
UniRef50_Q1EVV0 Cluster: Dihydrolipoyl dehydrogenase; n=6; Clost... 351 2e-95
UniRef50_A1HU83 Cluster: Dihydrolipoyl dehydrogenase; n=1; Therm... 350 4e-95
UniRef50_P54533 Cluster: Dihydrolipoyl dehydrogenase; n=41; Firm... 349 1e-94
UniRef50_Q59299 Cluster: Dihydrolipoyl dehydrogenase; n=6; Clost... 347 5e-94
UniRef50_Q18ZH8 Cluster: Dihydrolipoyl dehydrogenase; n=3; Desul... 347 5e-94
UniRef50_Q8CU56 Cluster: Dihydrolipoyl dehydrogenase; n=3; Bacil... 346 9e-94
UniRef50_A5EK01 Cluster: Dihydrolipoyl dehydrogenase; n=22; Bact... 345 2e-93
UniRef50_Q1AT12 Cluster: Dihydrolipoyl dehydrogenase; n=3; Bacte... 345 2e-93
UniRef50_A4J8D3 Cluster: Dihydrolipoyl dehydrogenase; n=1; Desul... 341 4e-92
UniRef50_Q67SE4 Cluster: Dihydrolipoyl dehydrogenase; n=2; Lacto... 339 1e-91
UniRef50_Q189R5 Cluster: Dihydrolipoyl dehydrogenase; n=3; Clost... 339 1e-91
UniRef50_Q5UWH2 Cluster: Dihydrolipoyl dehydrogenase 3; n=6; Hal... 330 4e-89
UniRef50_O84561 Cluster: Dihydrolipoyl dehydrogenase; n=9; Chlam... 329 9e-89
UniRef50_Q8R9D9 Cluster: Dihydrolipoyl dehydrogenase; n=3; Therm... 328 2e-88
UniRef50_Q6KCB6 Cluster: Dihydrolipoyl dehydrogenase; n=8; Plasm... 326 8e-88
UniRef50_A1W7R7 Cluster: Dihydrolipoamide dehydrogenase; n=58; B... 326 1e-87
UniRef50_A0L7L9 Cluster: Dihydrolipoyl dehydrogenase; n=1; Magne... 326 1e-87
UniRef50_Q0AVI0 Cluster: Dihydrolipoyl dehydrogenase; n=1; Syntr... 322 2e-86
UniRef50_Q8F290 Cluster: Dihydrolipoyl dehydrogenase; n=4; Lepto... 319 1e-85
UniRef50_P57303 Cluster: Dihydrolipoyl dehydrogenase; n=10; Bact... 318 3e-85
UniRef50_A4FLD8 Cluster: Dihydrolipoyl dehydrogenase; n=2; Bacte... 317 5e-85
UniRef50_A0M205 Cluster: Dihydrolipoyl dehydrogenase; n=2; Bacte... 316 9e-85
UniRef50_Q8K9T7 Cluster: Dihydrolipoyl dehydrogenase; n=33; Gamm... 316 9e-85
UniRef50_Q8VPK7 Cluster: Dihydrolipoamide dehydrogenase; n=43; S... 315 2e-84
UniRef50_Q1GHN7 Cluster: Dihydrolipoyl dehydrogenase; n=41; Bact... 315 2e-84
UniRef50_Q834J0 Cluster: Dihydrolipoyl dehydrogenase; n=3; Lacto... 314 5e-84
UniRef50_Q50068 Cluster: Dihydrolipoyl dehydrogenase; n=33; Acti... 312 1e-83
UniRef50_Q92Q96 Cluster: Dihydrolipoyl dehydrogenase; n=15; Alph... 312 1e-83
UniRef50_Q9KG96 Cluster: Dihydrolipoyl dehydrogenase; n=1; Bacil... 311 3e-83
UniRef50_Q68VU4 Cluster: Dihydrolipoyl dehydrogenase; n=11; Rick... 310 6e-83
UniRef50_Q1FMM1 Cluster: Dihydrolipoyl dehydrogenase; n=2; Clost... 308 2e-82
UniRef50_A6TMP2 Cluster: Dihydrolipoyl dehydrogenase; n=1; Alkal... 308 3e-82
UniRef50_Q9KES0 Cluster: Dihydrolipoyl dehydrogenase; n=1; Bacil... 305 2e-81
UniRef50_Q24PW4 Cluster: Dihydrolipoyl dehydrogenase; n=1; Desul... 304 4e-81
UniRef50_Q2JND9 Cluster: Dihydrolipoyl dehydrogenase; n=3; Cyano... 303 7e-81
UniRef50_Q8KCW2 Cluster: Dihydrolipoyl dehydrogenase; n=11; Chlo... 303 7e-81
UniRef50_Q49111 Cluster: Dihydrolipoamide dehydrogenase; n=7; ro... 300 6e-80
UniRef50_P50970 Cluster: Dihydrolipoyl dehydrogenase; n=25; Prot... 300 6e-80
UniRef50_Q9I1L9 Cluster: Dihydrolipoyl dehydrogenase; n=54; Prot... 300 6e-80
UniRef50_O34324 Cluster: Dihydrolipoyl dehydrogenase; n=13; Baci... 296 1e-78
UniRef50_Q9WYL2 Cluster: Dihydrolipoamide dehydrogenase; n=6; Ba... 295 1e-78
UniRef50_Q18CC1 Cluster: E3 component of acetoin dehydrogenase e... 295 2e-78
UniRef50_A1SYC1 Cluster: Dihydrolipoyl dehydrogenase; n=3; Prote... 294 3e-78
UniRef50_Q1Q2Y9 Cluster: Dihydrolipoyl dehydrogenase; n=1; Candi... 293 5e-78
UniRef50_Q9S2Q6 Cluster: Dihydrolipoyl dehydrogenase; n=32; Bact... 293 7e-78
UniRef50_Q8A2W9 Cluster: Dihydrolipoyl dehydrogenase; n=7; Bacte... 292 1e-77
UniRef50_Q8RDF1 Cluster: Dihydrolipoyl dehydrogenase; n=3; Therm... 289 1e-76
UniRef50_Q0RVL5 Cluster: Dihydrolipoyl dehydrogenanse; n=1; Rhod... 287 3e-76
UniRef50_Q2GDU8 Cluster: Dihydrolipoyl dehydrogenase; n=1; Neori... 285 2e-75
UniRef50_A5N930 Cluster: Dihydrolipoyl dehydrogenase; n=1; Clost... 285 2e-75
UniRef50_O66945 Cluster: Dihydrolipoyl dehydrogenase; n=2; Aquif... 280 5e-74
UniRef50_Q9YBC8 Cluster: Dihydrolipoyl dehydrogenase; n=2; Desul... 279 9e-74
UniRef50_Q6KH64 Cluster: Pyruvate dehydrogenase E3 component dih... 269 1e-70
UniRef50_Q2B857 Cluster: Dihydrolipoamide dehydrogenase; n=1; Ba... 269 1e-70
UniRef50_Q7MW44 Cluster: Dihydrolipoyl dehydrogenase; n=10; Bact... 266 9e-70
UniRef50_Q73M80 Cluster: Dihydrolipoyl dehydrogenase; n=1; Trepo... 265 2e-69
UniRef50_Q02733 Cluster: Increased recombination centers protein... 265 2e-69
UniRef50_A7BC28 Cluster: Putative uncharacterized protein; n=1; ... 262 1e-68
UniRef50_Q97CK3 Cluster: Dihydrolipoyl dehydrogenase; n=4; Therm... 262 1e-68
UniRef50_Q8ZUR5 Cluster: Pyruvate dehydrogenase E3; n=2; Pyrobac... 262 1e-68
UniRef50_Q4L6L9 Cluster: Dihydrolipoyl dehydrogenase; n=16; Stap... 261 3e-68
UniRef50_P16171 Cluster: Mercuric reductase (EC 1.16.1.1) (Hg(II... 260 5e-68
UniRef50_A3EPX8 Cluster: Dihydrolipoyl dehydrogenase; n=1; Lepto... 260 8e-68
UniRef50_Q82L58 Cluster: Dihydrolipoyl dehydrogenase; n=1; Strep... 258 2e-67
UniRef50_Q746U4 Cluster: Mercuric reductase; n=5; Geobacter|Rep:... 256 1e-66
UniRef50_Q6ARJ3 Cluster: Dihydrolipoyl dehydrogenase; n=1; Desul... 255 2e-66
UniRef50_Q8DTC8 Cluster: Dihydrolipoyl dehydrogenase; n=2; Strep... 254 3e-66
UniRef50_Q1VLA0 Cluster: Dihydrolipoyl dehydrogenase; n=1; Psych... 252 2e-65
UniRef50_Q8CQA3 Cluster: Dihydrolipoyl dehydrogenase; n=4; Staph... 251 3e-65
UniRef50_Q5QYX3 Cluster: Mercuric reductase, membrane-associated... 251 3e-65
UniRef50_A6CLP9 Cluster: Pyruvate dehydrogenase E3; n=1; Bacillu... 251 4e-65
UniRef50_P75393 Cluster: Dihydrolipoyl dehydrogenase; n=6; Mycop... 251 4e-65
UniRef50_A5IAB6 Cluster: Pyridine nucleotide-disulfide oxidoredu... 250 5e-65
UniRef50_A3DNK1 Cluster: Dihydrolipoamide dehydrogenase; n=1; St... 250 6e-65
UniRef50_Q98PG2 Cluster: DIHYDROLIPOAMIDE DEHYDROGENASE; n=8; My... 249 1e-64
UniRef50_A0B2P1 Cluster: Pyridine nucleotide-disulphide oxidored... 244 4e-63
UniRef50_Q1K375 Cluster: FAD-dependent pyridine nucleotide-disul... 242 1e-62
UniRef50_A5IXN5 Cluster: Dihydrolipoyl dehydrogenase; n=1; Mycop... 239 1e-61
UniRef50_Q090H7 Cluster: Soluble pyridine nucleotide transhydrog... 238 3e-61
UniRef50_Q41EB7 Cluster: FAD-dependent pyridine nucleotide-disul... 236 8e-61
UniRef50_A7HGF8 Cluster: Pyridine nucleotide-disulphide oxidored... 235 2e-60
UniRef50_Q311A9 Cluster: 2-oxoglutarate dehydrogenase, E3 compon... 234 5e-60
UniRef50_P30341 Cluster: Mercuric reductase (EC 1.16.1.1) (Hg(II... 233 6e-60
UniRef50_Q74A03 Cluster: Dihydrolipoyl dehydrogenase; n=2; Geoba... 232 2e-59
UniRef50_Q6MDA0 Cluster: Probable soluble pyridine nucleotide tr... 230 7e-59
UniRef50_Q0SUA0 Cluster: Pyridine nucleotide-disulphide oxidored... 229 1e-58
UniRef50_P35484 Cluster: Dihydrolipoyl dehydrogenase; n=3; Achol... 229 1e-58
UniRef50_A3I4Y3 Cluster: Acetoin dehydrogenase, E3 component, di... 229 1e-58
UniRef50_Q2S6F1 Cluster: Mercuric reductase; n=3; Bacteria|Rep: ... 228 2e-58
UniRef50_A3XLG1 Cluster: Dihydrolipoamide dehydrogenase; n=3; Ba... 228 2e-58
UniRef50_A4YI59 Cluster: Pyridine nucleotide-disulphide oxidored... 228 3e-58
UniRef50_Q0W154 Cluster: Pyruvate dehydrogenase complex E3, dihy... 227 4e-58
UniRef50_Q3VU31 Cluster: FAD-dependent pyridine nucleotide-disul... 227 5e-58
UniRef50_A0FRY7 Cluster: Pyridine nucleotide-disulphide oxidored... 225 2e-57
UniRef50_Q0LM28 Cluster: Pyridine nucleotide-disulphide oxidored... 224 4e-57
UniRef50_Q11LG9 Cluster: Pyridine nucleotide-disulphide oxidored... 223 6e-57
UniRef50_Q2HI16 Cluster: Putative uncharacterized protein; n=1; ... 223 1e-56
UniRef50_UPI00015BC7B4 Cluster: UPI00015BC7B4 related cluster; n... 222 1e-56
UniRef50_P66007 Cluster: Probable soluble pyridine nucleotide tr... 221 3e-56
UniRef50_Q98RI8 Cluster: DIHYDROLIPOAMIDE DEHYDROGENASE; n=1; My... 220 6e-56
UniRef50_Q1JWV4 Cluster: Pyridine nucleotide-disulphide oxidored... 220 6e-56
UniRef50_Q8G5E0 Cluster: Dihydrolipoyl dehydrogenase; n=4; Bifid... 219 1e-55
UniRef50_P23189 Cluster: Glutathione reductase; n=42; Proteobact... 219 1e-55
UniRef50_Q0F0Y4 Cluster: Soluble pyridine nucleotide transhydrog... 217 4e-55
UniRef50_Q3SL16 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 216 1e-54
UniRef50_Q2RZZ0 Cluster: Mercuric reductase; n=1; Salinibacter r... 215 2e-54
UniRef50_Q2JK69 Cluster: Pyridine nucleotide-disulfide oxidoredu... 214 5e-54
UniRef50_Q1PWS8 Cluster: Similar to NAD(P) oxidoreductase, FAD-c... 214 5e-54
UniRef50_Q8F4C6 Cluster: Dihydrolipoamide dehydrogenase; n=4; Le... 213 9e-54
UniRef50_Q1GLP7 Cluster: Pyridine nucleotide-disulphide oxidored... 213 9e-54
UniRef50_A3TPL4 Cluster: Pyridine nucleotide-disulphide oxidored... 213 9e-54
UniRef50_A3H831 Cluster: Pyridine nucleotide-disulphide oxidored... 212 2e-53
UniRef50_Q184K0 Cluster: Putative pyridine-nucleotide-disulfide ... 212 2e-53
UniRef50_A7CW98 Cluster: Pyridine nucleotide-disulphide oxidored... 212 2e-53
UniRef50_Q5V791 Cluster: Mercuric reductase; n=1; Haloarcula mar... 212 2e-53
UniRef50_Q1GTU0 Cluster: Glutathione reductase; n=12; Bacteria|R... 210 5e-53
UniRef50_Q74DK1 Cluster: Mercuric reductase; n=4; Bacteria|Rep: ... 210 6e-53
UniRef50_Q41CB3 Cluster: FAD-dependent pyridine nucleotide-disul... 210 6e-53
UniRef50_P96104 Cluster: Dihydrolipoyl transacetylase and lipoam... 210 6e-53
UniRef50_Q6SKC7 Cluster: Dihydrolipoamide dehydrogenase-like pro... 209 1e-52
UniRef50_A5FUY9 Cluster: Pyridine nucleotide-disulphide oxidored... 209 1e-52
UniRef50_Q0AAN2 Cluster: Pyridine nucleotide-disulphide oxidored... 208 2e-52
UniRef50_A4BJ37 Cluster: Mercuric reductase; n=2; unclassified G... 208 2e-52
UniRef50_Q6LLT9 Cluster: Soluble pyridine nucleotide transhydrog... 208 3e-52
UniRef50_Q99MD6 Cluster: Thioredoxin and glutathione reductase; ... 207 4e-52
UniRef50_A7HHC7 Cluster: Pyridine nucleotide-disulphide oxidored... 207 6e-52
UniRef50_Q311Y4 Cluster: Mercuric reductase, putative; n=4; Delt... 206 8e-52
UniRef50_Q11NC3 Cluster: Pyridine nucleotide-disulphide oxidored... 206 8e-52
UniRef50_A6CF61 Cluster: Soluble pyridine nucleotide transhydrog... 206 1e-51
UniRef50_P73059 Cluster: Mercuric reductase; n=11; Bacteria|Rep:... 205 2e-51
UniRef50_A6GLK6 Cluster: Glutathione reductase; n=1; Limnobacter... 204 3e-51
UniRef50_A2VRE9 Cluster: Dihydrolipoamide dehydrogenase; n=2; Bu... 204 4e-51
UniRef50_Q2SKE2 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 204 6e-51
UniRef50_Q8DD46 Cluster: Soluble pyridine nucleotide transhydrog... 204 6e-51
UniRef50_Q0W7Q8 Cluster: Dihydrolipoamide dehydrogenase; n=2; Eu... 203 1e-50
UniRef50_Q16881 Cluster: Thioredoxin reductase 1, cytoplasmic pr... 203 1e-50
UniRef50_UPI000038D9FE Cluster: COG1249: Pyruvate/2-oxoglutarate... 202 1e-50
UniRef50_Q11PG6 Cluster: Pyridine nucleotide-disulphide-related ... 202 1e-50
UniRef50_Q1GQ53 Cluster: Mercuric reductase MerA; n=91; Bacteria... 202 2e-50
UniRef50_UPI00006A2AB5 Cluster: UPI00006A2AB5 related cluster; n... 201 4e-50
UniRef50_Q1AV54 Cluster: Pyridine nucleotide-disulphide oxidored... 200 5e-50
UniRef50_Q9HLL9 Cluster: Dihydrolipoamide dehydrogenase componen... 200 7e-50
UniRef50_Q8E285 Cluster: Pyridine nucleotide-disulphide oxidored... 200 9e-50
UniRef50_A7I8G1 Cluster: Pyridine nucleotide-disulphide oxidored... 200 9e-50
UniRef50_Q98C99 Cluster: Mercuric reductase; n=4; Proteobacteria... 199 1e-49
UniRef50_A3ZMG9 Cluster: Mercuric reductase; n=1; Blastopirellul... 199 1e-49
UniRef50_A0SNY8 Cluster: Mercuric reductase; n=1; uncultured eur... 198 2e-49
UniRef50_A2RPR6 Cluster: 2-oxoglutarate dehydrogenase, E3 compon... 198 3e-49
UniRef50_Q8KB36 Cluster: Dihydrolipoamide dehydrogenase; n=2; Ch... 196 1e-48
UniRef50_Q978K3 Cluster: Pyruvate dehydrogenase E3 / dihydrolipo... 196 1e-48
UniRef50_A7BE73 Cluster: Putative uncharacterized protein; n=1; ... 196 1e-48
UniRef50_A3ESJ6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 196 1e-48
UniRef50_Q2NDS9 Cluster: Mercuric reductase, putative; n=2; Eryt... 195 2e-48
UniRef50_Q5ZY02 Cluster: Glutathione reductase; n=4; Legionella ... 195 3e-48
UniRef50_Q5ZV78 Cluster: Mercuric reductase; n=5; Legionella pne... 195 3e-48
UniRef50_A6Q9K6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 195 3e-48
UniRef50_Q1K470 Cluster: Pyridine nucleotide-disulphide oxidored... 194 3e-48
UniRef50_A7JHZ5 Cluster: Soluble pyridine nucleotide transhydrog... 194 3e-48
UniRef50_Q7P4B5 Cluster: Mercuric reductase; n=3; Fusobacterium ... 193 8e-48
UniRef50_A3TUM1 Cluster: Glutathione-disulfide reductase; n=2; A... 192 2e-47
UniRef50_Q2VHK2 Cluster: Oxidoreductase; n=11; Lactobacillales|R... 192 2e-47
UniRef50_UPI000023D207 Cluster: hypothetical protein FG05450.1; ... 191 3e-47
UniRef50_A5EH40 Cluster: Putative mercuric reductase protein; n=... 191 3e-47
UniRef50_Q5P1X0 Cluster: Putative uncharacterized protein; n=1; ... 190 5e-47
UniRef50_Q4SQZ1 Cluster: Chromosome 11 SCAF14528, whole genome s... 190 7e-47
UniRef50_Q6AQZ1 Cluster: Related to mercuric reductase; n=17; Pr... 190 7e-47
UniRef50_Q4A6P9 Cluster: Putative mercuric reductase; n=1; Mycop... 189 1e-46
UniRef50_A7D615 Cluster: Pyridine nucleotide-disulphide oxidored... 189 1e-46
UniRef50_Q01WF2 Cluster: FAD-dependent pyridine nucleotide-disul... 189 2e-46
UniRef50_A6SWJ7 Cluster: Mercury(II) reductase; n=50; Bacteria|R... 189 2e-46
UniRef50_A3UIQ0 Cluster: Probable glutathione reductase; n=1; Oc... 189 2e-46
UniRef50_A1AVW4 Cluster: Pyridine nucleotide-disulphide oxidored... 189 2e-46
UniRef50_Q8ZUT2 Cluster: Mercuric reductase; n=4; Thermoproteace... 188 2e-46
UniRef50_Q58E89 Cluster: MGC84926 protein; n=7; cellular organis... 188 3e-46
UniRef50_Q5VGY1 Cluster: Dihydrolipoamide dehydrogenase; n=3; Pl... 187 5e-46
UniRef50_P48639 Cluster: Glutathione reductase; n=5; cellular or... 186 2e-45
UniRef50_A7GZF3 Cluster: Probable pyridine nucleotide-disulfide ... 184 4e-45
UniRef50_A4IXR1 Cluster: Glutathione-disulfide reductase; n=11; ... 184 4e-45
UniRef50_Q9NNW7 Cluster: Thioredoxin reductase 2, mitochondrial ... 184 4e-45
UniRef50_A6U5L4 Cluster: Pyridine nucleotide-disulphide oxidored... 183 8e-45
UniRef50_Q7V2B4 Cluster: Probable glutathione reductase; n=5; Pr... 183 1e-44
UniRef50_P00390 Cluster: Glutathione reductase, mitochondrial pr... 183 1e-44
UniRef50_Q7NCV5 Cluster: Glr2871 protein; n=3; Cyanobacteria|Rep... 182 3e-44
UniRef50_A1SIG2 Cluster: FAD-dependent pyridine nucleotide-disul... 182 3e-44
UniRef50_Q6S4W1 Cluster: Dihydrolipoamide dehydrogenase precurso... 182 3e-44
UniRef50_P41921 Cluster: Glutathione reductase; n=39; cellular o... 182 3e-44
UniRef50_O05940 Cluster: Probable dihydrolipoyl dehydrogenase; n... 182 3e-44
UniRef50_A0ZGC8 Cluster: Glutathione reductase; n=2; Nostocaceae... 181 3e-44
UniRef50_A0Q826 Cluster: Dihydrolipoamide dehydrogenase; n=7; Fr... 181 4e-44
UniRef50_Q9YBZ2 Cluster: Mercuric reductase; n=1; Aeropyrum pern... 181 4e-44
UniRef50_A3U327 Cluster: Regulatory protein; n=4; Alphaproteobac... 180 6e-44
UniRef50_Q4J868 Cluster: Mercuric reductase; n=10; Archaea|Rep: ... 180 8e-44
UniRef50_Q6A6B6 Cluster: Pyridine nucleotide-disulphide oxidored... 180 1e-43
UniRef50_Q9RKH2 Cluster: Putative oxidoreductase; n=1; Streptomy... 179 2e-43
UniRef50_Q2IA26 Cluster: Chloroplast glutathione reductase; n=1;... 179 2e-43
UniRef50_A6WBN3 Cluster: Pyridine nucleotide-disulphide oxidored... 178 2e-43
UniRef50_Q5NN75 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 178 3e-43
UniRef50_A0LCP2 Cluster: Pyridine nucleotide-disulphide oxidored... 178 3e-43
UniRef50_P08332 Cluster: Mercuric reductase (EC 1.16.1.1) (Hg(II... 178 3e-43
UniRef50_Q041G8 Cluster: Acetoin/pyruvate dehydrogenase complex,... 177 7e-43
UniRef50_A5FRC9 Cluster: FAD-dependent pyridine nucleotide-disul... 177 7e-43
UniRef50_A1B892 Cluster: Pyridine nucleotide-disulphide oxidored... 177 7e-43
UniRef50_P48638 Cluster: Glutathione reductase; n=57; Bacteria|R... 177 7e-43
UniRef50_A3ZHU0 Cluster: Probable pyridine nucleotide-disulfide ... 176 1e-42
UniRef50_A2C124 Cluster: Probable glutathione reductase; n=2; Pr... 176 1e-42
UniRef50_P77212 Cluster: Probable pyridine nucleotide-disulfide ... 176 1e-42
UniRef50_UPI00015BD547 Cluster: UPI00015BD547 related cluster; n... 175 2e-42
UniRef50_Q83N49 Cluster: Pyridine nucleotide-disulphide oxidored... 175 2e-42
UniRef50_Q5FQ43 Cluster: Glutathione reductase; n=3; Acetobacter... 175 2e-42
UniRef50_Q97PL8 Cluster: Oxidoreductase, pyridine nucleotide-dis... 174 4e-42
UniRef50_Q60151 Cluster: Glutathione reductase; n=31; Bacteria|R... 173 9e-42
UniRef50_Q5WE89 Cluster: Acetoin dehydrogenase E3 component; n=1... 173 1e-41
UniRef50_A7IDF4 Cluster: Pyridine nucleotide-disulphide oxidored... 173 1e-41
UniRef50_A4YFQ3 Cluster: Pyridine nucleotide-disulphide oxidored... 173 1e-41
UniRef50_A4AEI6 Cluster: Putative oxidoreductase; n=1; marine ac... 172 2e-41
UniRef50_Q4JCC0 Cluster: Dihydrolipoamide dehydrogenase; n=4; Su... 172 2e-41
UniRef50_A4MI92 Cluster: Pyridine nucleotide-disulphide oxidored... 171 5e-41
UniRef50_Q17745 Cluster: Thioredoxin reductase 1; n=6; Bilateria... 171 5e-41
UniRef50_P42770 Cluster: Glutathione reductase, chloroplast prec... 171 5e-41
UniRef50_Q0C555 Cluster: Pyridine nucleotide-disulfide oxidoredu... 170 8e-41
UniRef50_Q31FJ0 Cluster: FAD-dependent pyridine nucleotide-disul... 169 1e-40
UniRef50_Q8NLD1 Cluster: Dihydrolipoamide dehydrogenase/glutathi... 169 2e-40
UniRef50_A1SH76 Cluster: Pyridine nucleotide-disulphide oxidored... 168 3e-40
UniRef50_Q8PS09 Cluster: Dihydrolipoamide dehydrogenase; n=5; Eu... 167 4e-40
UniRef50_A0J8I0 Cluster: FAD-dependent pyridine nucleotide-disul... 167 8e-40
UniRef50_Q7USN6 Cluster: Glutathione reductase; n=1; Pirellula s... 166 1e-39
UniRef50_Q03GQ4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 166 1e-39
UniRef50_A2RNK4 Cluster: Pyridine nucleotide-disulfide oxidoredu... 166 1e-39
UniRef50_Q8DIH9 Cluster: Glutathione reductase; n=16; Cyanobacte... 165 3e-39
UniRef50_Q82WB8 Cluster: Pyridine nucleotide-disulfide oxidoredu... 164 4e-39
UniRef50_A1S189 Cluster: FAD-dependent pyridine nucleotide-disul... 164 5e-39
UniRef50_A3XHA5 Cluster: Regulatory protein; n=4; Flavobacteriac... 162 2e-38
UniRef50_P39051 Cluster: Trypanothione reductase (EC 1.8.1.12) (... 162 2e-38
UniRef50_Q5ZZX0 Cluster: Dihydrolipoamide dehydrogenase; n=6; My... 161 4e-38
UniRef50_Q1DFL4 Cluster: Mercuric reductase, truncated; n=1; Myx... 161 4e-38
UniRef50_Q97XZ3 Cluster: Dihydrolipoamide dehydrogenase; n=2; Su... 161 4e-38
UniRef50_Q1K1S1 Cluster: FAD-dependent pyridine nucleotide-disul... 161 5e-38
UniRef50_A6G2P8 Cluster: Dihydrolipoamide dehydrogenase; n=1; Pl... 161 5e-38
UniRef50_A4VK61 Cluster: Dihydrolipoamide dehydrogenase 3; n=1; ... 161 5e-38
UniRef50_A6CEV1 Cluster: Glutathione reductase; n=1; Planctomyce... 160 9e-38
UniRef50_A3M5D5 Cluster: Dihydrolipoamide dehydrogenase; n=1; Ac... 160 9e-38
UniRef50_Q3A4H5 Cluster: Dihydrolipoamide dehydrogenase (E3) com... 159 1e-37
UniRef50_Q2JF62 Cluster: Pyridine nucleotide-disulphide oxidored... 159 2e-37
UniRef50_Q1LHF0 Cluster: FAD-dependent pyridine nucleotide-disul... 159 2e-37
UniRef50_Q97C54 Cluster: Mercuric reductase; n=2; Thermoplasma|R... 159 2e-37
UniRef50_Q97Z19 Cluster: Dihydrolipoamide dehydrogenase; n=4; Su... 158 3e-37
UniRef50_O54274 Cluster: ORF503 protein; n=6; Staphylococcus|Rep... 158 4e-37
UniRef50_A1SIE7 Cluster: Pyridine nucleotide-disulphide oxidored... 158 4e-37
UniRef50_A6Q9K4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 157 6e-37
UniRef50_Q28MH1 Cluster: Pyridine nucleotide-disulphide oxidored... 157 8e-37
UniRef50_P30635 Cluster: Probable glutathione reductase 2; n=2; ... 156 1e-36
UniRef50_A7BMW7 Cluster: Dihydrolipoamide dehydrogenase; n=1; Be... 156 1e-36
UniRef50_A1D1G1 Cluster: Glutathione reductase; n=7; cellular or... 156 1e-36
UniRef50_A7IAT2 Cluster: FAD-dependent pyridine nucleotide-disul... 156 1e-36
UniRef50_Q8Y768 Cluster: Lmo1433 protein; n=12; Listeria|Rep: Lm... 155 3e-36
UniRef50_A7CCD3 Cluster: Pyridine nucleotide-disulphide oxidored... 155 3e-36
UniRef50_A4T107 Cluster: Pyridine nucleotide-disulphide oxidored... 155 3e-36
UniRef50_Q4FXL9 Cluster: Dihydrolipoamide dehydrogenase, putativ... 155 3e-36
UniRef50_A0E909 Cluster: Chromosome undetermined scaffold_83, wh... 155 3e-36
UniRef50_A2R0R4 Cluster: Catalytic activity: Hg + NADP(+) + H(+)... 154 4e-36
UniRef50_Q6BPI1 Cluster: Glutathione reductase; n=6; Saccharomyc... 154 4e-36
UniRef50_Q88ZF2 Cluster: Glutathione reductase; n=4; Lactobacill... 154 6e-36
UniRef50_Q7RRZ4 Cluster: Dihydrolipoamide dehydrogenase; n=3; Pl... 154 6e-36
UniRef50_Q4UCW3 Cluster: Thioredoxin reductase, putative; n=3; P... 154 6e-36
UniRef50_Q6NIX1 Cluster: Dihydrolipoamide dehydrogenase; n=21; A... 153 1e-35
UniRef50_A5KTA3 Cluster: Pyridine nucleotide-disulphide oxidored... 153 1e-35
UniRef50_A4CGZ8 Cluster: Regulatory protein; n=5; Flavobacteriac... 153 1e-35
UniRef50_A5UY00 Cluster: FAD-dependent pyridine nucleotide-disul... 152 2e-35
UniRef50_Q4UWG8 Cluster: Reductase; n=10; Gammaproteobacteria|Re... 151 3e-35
UniRef50_Q03XL9 Cluster: Glutathione reductase; n=1; Leuconostoc... 151 4e-35
UniRef50_Q8H6T2 Cluster: Thioredoxin reductase TR1; n=1; Chlamyd... 151 4e-35
UniRef50_Q6L2F3 Cluster: Mercuric reductase; n=3; Thermoplasmata... 150 1e-34
UniRef50_A7BTB7 Cluster: Dihydrolipoyl dehydrogenase; n=1; Beggi... 149 1e-34
UniRef50_Q25861 Cluster: Thioredoxin reductase; n=14; Apicomplex... 149 2e-34
UniRef50_UPI0000510280 Cluster: COG1249: Pyruvate/2-oxoglutarate... 148 4e-34
UniRef50_A0H3T5 Cluster: FAD-dependent pyridine nucleotide-disul... 147 7e-34
UniRef50_Q88W40 Cluster: Glutathione reductase; n=2; Bacilli|Rep... 146 2e-33
UniRef50_Q8TIX6 Cluster: Glutathione reductase; n=6; Methanosarc... 145 3e-33
UniRef50_Q4FTN7 Cluster: Dihydrolipoamide dehydrogenase; n=2; Ps... 144 5e-33
UniRef50_Q5FK23 Cluster: Glutathione reductase; n=1; Lactobacill... 144 6e-33
UniRef50_A4BQ38 Cluster: Dihydrolipoamide dehydrogenase; n=1; Ni... 143 8e-33
UniRef50_A3CSE1 Cluster: Pyridine nucleotide-disulphide oxidored... 141 3e-32
UniRef50_Q2JEH1 Cluster: Pyridine nucleotide-disulphide oxidored... 140 6e-32
UniRef50_Q6XYS2 Cluster: Dihydrolipoamide dehydrogensae; n=1; Sp... 140 1e-31
UniRef50_Q57YU0 Cluster: Dihydrolipoamide dehydrogenase, point m... 140 1e-31
UniRef50_A1UEQ3 Cluster: Pyridine nucleotide-disulphide oxidored... 138 2e-31
UniRef50_A5CS71 Cluster: Putative oxidoreductase; n=1; Clavibact... 138 3e-31
UniRef50_Q6KG49 Cluster: Mitochondrial thioredoxin reductase 2; ... 138 4e-31
UniRef50_A3VZL9 Cluster: Glutathione-disulfide reductase; n=1; R... 137 5e-31
UniRef50_A3GI90 Cluster: Glutathione reductase; n=1; Pichia stip... 137 7e-31
UniRef50_Q9KNU2 Cluster: Pyridine nucleotide-disulfide oxidoredu... 136 9e-31
UniRef50_A1W5P4 Cluster: Pyridine nucleotide-disulphide oxidored... 135 3e-30
UniRef50_A2TYU9 Cluster: Regulatory protein; n=1; Polaribacter d... 134 5e-30
UniRef50_A0JSP4 Cluster: Pyridine nucleotide-disulphide oxidored... 133 9e-30
UniRef50_A6DK63 Cluster: Dihydrolipoamide dehydrogenase; n=1; Le... 132 2e-29
UniRef50_UPI0000F2E9A5 Cluster: PREDICTED: similar to extracellu... 132 2e-29
UniRef50_Q1EZ89 Cluster: FAD-dependent pyridine nucleotide-disul... 132 2e-29
UniRef50_Q7NDN4 Cluster: Gll4201 protein; n=1; Gloeobacter viola... 132 3e-29
UniRef50_Q6AAX8 Cluster: Pyridine nucleotide-disulphide oxidored... 131 4e-29
UniRef50_Q8TE01 Cluster: DERP12; n=1; Homo sapiens|Rep: DERP12 -... 130 6e-29
UniRef50_Q9CH92 Cluster: Glutathione reductase; n=3; Lactococcus... 128 3e-28
UniRef50_Q26GG1 Cluster: Dihydrolipoamide dehydrogenase; n=1; Fl... 128 3e-28
UniRef50_Q115D3 Cluster: Pyridine nucleotide-disulphide oxidored... 128 3e-28
UniRef50_Q28QN1 Cluster: FAD-dependent pyridine nucleotide-disul... 128 4e-28
UniRef50_A0R0K9 Cluster: Oxidoreductase; n=1; Mycobacterium smeg... 128 4e-28
UniRef50_A0C460 Cluster: Chromosome undetermined scaffold_148, w... 127 8e-28
UniRef50_UPI000051037B Cluster: COG1249: Pyruvate/2-oxoglutarate... 126 1e-27
UniRef50_Q6F7X9 Cluster: Putative pyridine nucleotide-disulfide ... 126 1e-27
UniRef50_Q41E05 Cluster: FAD-dependent pyridine nucleotide-disul... 126 1e-27
UniRef50_Q03HI1 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 125 2e-27
UniRef50_Q4Q5Z7 Cluster: 2-oxoglutarate dehydrogenase, e3 compon... 124 4e-27
UniRef50_UPI000150AB3A Cluster: Pyridine nucleotide-disulphide o... 123 9e-27
UniRef50_Q3XWK1 Cluster: FAD-dependent pyridine nucleotide-disul... 122 2e-26
UniRef50_Q584K1 Cluster: Dihydrolipoamide dehydrogenase, putativ... 122 2e-26
UniRef50_Q4Q5Z6 Cluster: Acetoin dehydrogenase e3 component-like... 122 2e-26
UniRef50_Q4L3S1 Cluster: Mercuric reductase homologue; n=2; Stap... 121 4e-26
UniRef50_Q88SV9 Cluster: Glutathione reductase; n=10; Lactobacil... 120 9e-26
UniRef50_Q97Y24 Cluster: Dihydrolipoamide dehydrogenase; n=2; Su... 120 1e-25
UniRef50_Q83HF4 Cluster: Dihydrolipoamide dehydrogenase; n=2; Tr... 119 2e-25
UniRef50_Q94655 Cluster: Glutathione reductase; n=11; Plasmodium... 119 2e-25
UniRef50_O43998 Cluster: Glutathione reductase homolog; n=1; Tox... 117 6e-25
UniRef50_A0CQA5 Cluster: Chromosome undetermined scaffold_24, wh... 117 8e-25
UniRef50_Q3JCH1 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 113 1e-23
UniRef50_UPI0000E4A425 Cluster: PREDICTED: similar to Dihydrolip... 112 2e-23
UniRef50_Q38UF8 Cluster: Glutathione reductase; n=3; Lactobacill... 111 3e-23
UniRef50_Q8G3X6 Cluster: Possible class I pyridine nucleotide-di... 111 4e-23
UniRef50_A5UKW4 Cluster: Dihydrolipoamide dehydrogenase; n=1; Me... 110 9e-23
UniRef50_A3CSS3 Cluster: FAD-dependent pyridine nucleotide-disul... 110 9e-23
UniRef50_A3VQD6 Cluster: Dihydrolipoamide dehydrogenase; n=5; Al... 109 2e-22
UniRef50_UPI0000E4A80A Cluster: PREDICTED: similar to thioredoxi... 109 2e-22
UniRef50_Q072K0 Cluster: Glutathione reductase; n=2; Papilionoid... 108 4e-22
UniRef50_Q4CB64 Cluster: FAD-dependent pyridine nucleotide-disul... 107 5e-22
UniRef50_A7D8C3 Cluster: FAD-dependent pyridine nucleotide-disul... 107 7e-22
UniRef50_Q8VKD9 Cluster: Mercuric reductase/transcriptional regu... 107 9e-22
UniRef50_A5WGB8 Cluster: Pyridine nucleotide-disulphide oxidored... 106 1e-21
UniRef50_O27685 Cluster: Dihydrolipoamide dehydrogenase; n=1; Me... 103 1e-20
UniRef50_Q56839 Cluster: 2-oxopropyl-CoM reductase, carboxylatin... 102 2e-20
UniRef50_Q8YQ97 Cluster: Mercuric reductase; n=4; Nostocaceae|Re... 100 8e-20
UniRef50_Q0US44 Cluster: Putative uncharacterized protein; n=1; ... 100 1e-19
UniRef50_Q0RQF2 Cluster: Putative oxidoreductase; putative metal... 98 5e-19
UniRef50_Q9V0X9 Cluster: NoxA-2 NADH oxidase; n=4; Thermococcace... 97 7e-19
UniRef50_A5GRM0 Cluster: Putative soluble pyridine nucleotide tr... 97 1e-18
UniRef50_Q3UY43 Cluster: Adult male olfactory brain cDNA, RIKEN ... 96 2e-18
UniRef50_Q8DWC4 Cluster: Putative glutathione reductase; n=1; St... 94 9e-18
UniRef50_UPI00006CFB8B Cluster: Pyridine nucleotide-disulphide o... 93 2e-17
UniRef50_Q2NFE3 Cluster: Predicted dihydrolipoamide dehydrogenas... 92 4e-17
UniRef50_Q1JZ87 Cluster: FAD-dependent pyridine nucleotide-disul... 91 5e-17
UniRef50_Q047B7 Cluster: Glutathione reductase; n=4; Lactobacill... 90 1e-16
UniRef50_Q926L9 Cluster: Pli0040 protein; n=5; Bacilli|Rep: Pli0... 88 4e-16
UniRef50_Q926L6 Cluster: Pli0044 protein; n=4; Bacillales|Rep: P... 88 4e-16
UniRef50_Q9M5K2-2 Cluster: Isoform 2 of Q9M5K2 ; n=1; Arabidopsi... 87 8e-16
UniRef50_Q3Y0G7 Cluster: FAD-dependent pyridine nucleotide-disul... 87 1e-15
UniRef50_Q2FS82 Cluster: FAD-dependent pyridine nucleotide-disul... 87 1e-15
UniRef50_Q5UXD9 Cluster: Dihydrolipoamide dehydrogenase; n=3; Ha... 86 2e-15
UniRef50_Q8KS25 Cluster: NADH:polysulfide oxidoreductase; n=1; T... 85 4e-15
UniRef50_A2ST66 Cluster: FAD-dependent pyridine nucleotide-disul... 85 5e-15
UniRef50_A5HII0 Cluster: Glutathione reductase; n=4; Magnoliophy... 84 7e-15
UniRef50_Q8TX29 Cluster: Dihydrolipoamide dehydrogenase; n=1; Me... 84 9e-15
UniRef50_UPI0000ECC431 Cluster: Glutathione reductase, mitochond... 83 1e-14
UniRef50_Q8R8V6 Cluster: Uncharacterized NAD(FAD)-dependent dehy... 83 2e-14
UniRef50_UPI00006D9A19 Cluster: COG1249: Pyruvate/2-oxoglutarate... 82 3e-14
UniRef50_Q6AJ61 Cluster: Related to NADH oxidase; n=4; Deltaprot... 82 3e-14
UniRef50_A5KJ20 Cluster: Putative uncharacterized protein; n=2; ... 82 3e-14
UniRef50_Q8KAS7 Cluster: NADH oxidase, putative; n=10; Bacteria|... 81 5e-14
UniRef50_O28421 Cluster: NADH oxidase; n=4; cellular organisms|R... 81 7e-14
UniRef50_Q2NEC3 Cluster: Predicted NAD(FAD)-dependent dehydrogen... 81 9e-14
UniRef50_Q9R9P5 Cluster: MocF; n=8; Rhizobiales|Rep: MocF - Rhiz... 80 1e-13
UniRef50_A0LQI9 Cluster: FAD-dependent pyridine nucleotide-disul... 80 2e-13
UniRef50_A7EZF7 Cluster: Putative uncharacterized protein; n=1; ... 80 2e-13
UniRef50_A4XHJ3 Cluster: FAD-dependent pyridine nucleotide-disul... 79 2e-13
UniRef50_P08655 Cluster: Uncharacterized 19.7 kDa protein in mer... 79 4e-13
UniRef50_O67007 Cluster: NADH oxidase; n=2; Aquifex aeolicus|Rep... 78 6e-13
UniRef50_Q4L4Y7 Cluster: Coenzyme A disulfide reductase; n=16; S... 78 6e-13
UniRef50_Q9KLU7 Cluster: NADH oxidase, putative; n=32; Bacteria|... 77 1e-12
UniRef50_Q58065 Cluster: Putative NADH oxidase; n=7; Euryarchaeo... 77 1e-12
UniRef50_Q19655 Cluster: Putative uncharacterized protein F20D6.... 76 2e-12
UniRef50_Q186H7 Cluster: Rubredoxin; n=3; Bacteria|Rep: Rubredox... 76 2e-12
UniRef50_Q74DS8 Cluster: Pyridine nucleotide-disulphide oxidored... 75 3e-12
UniRef50_A1RWH3 Cluster: FAD-dependent pyridine nucleotide-disul... 75 4e-12
UniRef50_A6Q8K3 Cluster: FAD-dependent pyridine nucleotide-disul... 74 8e-12
UniRef50_A0Y5X5 Cluster: Nitrite reductase, large subunit, NAD(P... 74 1e-11
UniRef50_Q9HJX5 Cluster: NADH peroxidase related protein; n=2; T... 74 1e-11
UniRef50_Q8R6T3 Cluster: Uncharacterized NAD(FAD)-dependent dehy... 73 1e-11
UniRef50_Q88X11 Cluster: NADH peroxidase; n=1; Lactobacillus pla... 73 1e-11
UniRef50_Q7MXK3 Cluster: Pyridine nucleotide-disulphide oxidored... 73 1e-11
UniRef50_Q2RIY5 Cluster: FAD-dependent pyridine nucleotide-disul... 73 1e-11
UniRef50_A7LUS3 Cluster: Putative uncharacterized protein; n=1; ... 73 2e-11
UniRef50_A4XLJ4 Cluster: FAD-dependent pyridine nucleotide-disul... 73 2e-11
UniRef50_Q3CIN5 Cluster: FAD-dependent pyridine nucleotide-disul... 72 4e-11
UniRef50_A6P1A8 Cluster: Rubredoxin; n=1; Bacteroides capillosus... 72 4e-11
UniRef50_A5ZWV3 Cluster: Putative uncharacterized protein; n=1; ... 72 4e-11
UniRef50_A4J3D6 Cluster: FAD-dependent pyridine nucleotide-disul... 72 4e-11
UniRef50_Q1JZA8 Cluster: FAD-dependent pyridine nucleotide-disul... 71 5e-11
UniRef50_A1AWX1 Cluster: Nitrite reductase (NAD(P)H), large subu... 71 5e-11
UniRef50_Q64E99 Cluster: NADH oxidase; n=1; uncultured archaeon ... 71 5e-11
UniRef50_Q0LDK4 Cluster: FAD-dependent pyridine nucleotide-disul... 71 7e-11
UniRef50_Q82ZQ9 Cluster: Coenzyme A disulfide reductase; n=9; Ba... 71 9e-11
UniRef50_A7B7I3 Cluster: Putative uncharacterized protein; n=1; ... 70 1e-10
UniRef50_A6PTB1 Cluster: FAD-dependent pyridine nucleotide-disul... 70 1e-10
UniRef50_Q6AQU4 Cluster: Related to NADH oxidase; n=1; Desulfota... 70 2e-10
UniRef50_Q1FP75 Cluster: FAD-dependent pyridine nucleotide-disul... 69 2e-10
UniRef50_A2E972 Cluster: Pyridine nucleotide-disulphide oxidored... 69 2e-10
UniRef50_Q4J224 Cluster: FAD-dependent pyridine nucleotide-disul... 69 3e-10
UniRef50_Q0AVA6 Cluster: Rubredoxin; n=8; Clostridiales|Rep: Rub... 69 3e-10
UniRef50_A3Z853 Cluster: NADH oxidase; n=1; Synechococcus sp. RS... 69 3e-10
UniRef50_Q9V1W4 Cluster: SoxA sarcosine oxidase, subunit alpha; ... 69 3e-10
UniRef50_Q2LQ41 Cluster: Pyridine nucleotide oxidoreductase; n=1... 69 4e-10
UniRef50_P42454 Cluster: Rubredoxin-NAD(+) reductase; n=4; Acine... 69 4e-10
UniRef50_UPI0001597145 Cluster: NasB; n=1; Bacillus amyloliquefa... 68 5e-10
UniRef50_P42433 Cluster: Assimilatory nitrate reductase electron... 68 5e-10
UniRef50_A7H8D2 Cluster: FAD-dependent pyridine nucleotide-disul... 68 7e-10
UniRef50_A6M1W0 Cluster: FAD-dependent pyridine nucleotide-disul... 67 9e-10
UniRef50_O29847 Cluster: NADH oxidase; n=2; cellular organisms|R... 67 9e-10
UniRef50_Q6F0G4 Cluster: NADH oxidase; n=1; Mesoplasma florum|Re... 67 1e-09
UniRef50_Q3WDA8 Cluster: Similar to Pyruvate/2-oxoglutarate dehy... 67 1e-09
UniRef50_A6FHC0 Cluster: Dihydrolipoamide dehydrogenase; n=1; Mo... 67 1e-09
UniRef50_Q0W6R5 Cluster: Putative NADH dehydrogenase; n=1; uncul... 67 1e-09
UniRef50_P37061 Cluster: NADH oxidase; n=12; Bacteria|Rep: NADH ... 67 1e-09
UniRef50_Q5FJ98 Cluster: Peroxidase; n=8; Lactobacillales|Rep: P... 66 2e-09
UniRef50_A1RCI0 Cluster: Putative ferredoxin reductase; n=1; Art... 66 2e-09
UniRef50_P42435 Cluster: Nitrite reductase [NAD(P)H]; n=34; Bact... 66 2e-09
UniRef50_Q3A484 Cluster: Uncharacterized NAD(FAD)-dependent dehy... 66 2e-09
UniRef50_Q3T557 Cluster: NADH oxidase-like protein; n=1; Acidith... 66 2e-09
UniRef50_Q890W4 Cluster: Rubredoxin; n=1; Clostridium tetani|Rep... 66 3e-09
UniRef50_A1U0G0 Cluster: FAD-dependent pyridine nucleotide-disul... 66 3e-09
UniRef50_A1HNI3 Cluster: FAD-dependent pyridine nucleotide-disul... 66 3e-09
UniRef50_A0VEF3 Cluster: FAD-dependent pyridine nucleotide-disul... 66 3e-09
UniRef50_A6L317 Cluster: Pyridine nucleotide-disulphide oxidored... 65 4e-09
UniRef50_P75389 Cluster: Probable NADH oxidase; n=6; Mycoplasma|... 65 4e-09
UniRef50_Q9UYU5 Cluster: Coenzyme A disulfide reductase; n=6; Eu... 65 4e-09
UniRef50_Q8XLM7 Cluster: Rubredoxin; n=3; Clostridium perfringen... 65 5e-09
UniRef50_Q7N4V5 Cluster: Similar to 3-phenylpropionate dioxygena... 65 5e-09
UniRef50_Q3A7F5 Cluster: Uncharacterized NAD(FAD)-dependent dehy... 65 5e-09
UniRef50_Q3Y1R2 Cluster: FAD-dependent pyridine nucleotide-disul... 64 6e-09
UniRef50_A5D1H2 Cluster: Uncharacterized NAD(FAD)-dependent dehy... 64 6e-09
UniRef50_Q8ZVB1 Cluster: NADH oxidase; n=5; Thermoproteaceae|Rep... 64 6e-09
UniRef50_Q89RG4 Cluster: Blr2808 protein; n=3; Rhizobiales|Rep: ... 64 8e-09
UniRef50_Q39D64 Cluster: FAD-dependent pyridine nucleotide-disul... 64 8e-09
UniRef50_Q59917 Cluster: NADH oxidase; n=39; Bacteria|Rep: NADH ... 64 8e-09
UniRef50_A4SYM8 Cluster: FAD-dependent pyridine nucleotide-disul... 64 8e-09
UniRef50_A5IY35 Cluster: NADH oxidase; n=4; Mycoplasma|Rep: NADH... 64 1e-08
UniRef50_Q98RI6 Cluster: NADH OXIDASE; n=9; Mycoplasma|Rep: NADH... 63 1e-08
UniRef50_Q3IBR1 Cluster: NADH oxidase; n=1; uncultured sulfate-r... 63 1e-08
UniRef50_A4XJL1 Cluster: FAD-dependent pyridine nucleotide-disul... 63 1e-08
UniRef50_UPI00015BAF0C Cluster: FAD-dependent pyridine nucleotid... 63 2e-08
UniRef50_Q88VV8 Cluster: NADH oxidase; n=1; Lactobacillus planta... 63 2e-08
UniRef50_Q81TK8 Cluster: Pyridine nucleotide-disulfide oxidoredu... 63 2e-08
UniRef50_Q7UWN5 Cluster: Nitrite reductase [NAD(P)H] large subun... 63 2e-08
UniRef50_Q6FB26 Cluster: Putative nitrate reductase (Electron tr... 63 2e-08
UniRef50_Q0SDC8 Cluster: Probable FAD-dependent oxidoreductase; ... 63 2e-08
UniRef50_Q02VZ8 Cluster: Uncharacterized NAD(FAD)-dependent dehy... 63 2e-08
UniRef50_A3ERW1 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 63 2e-08
UniRef50_Q8R5Q5 Cluster: NADH:flavin oxidoreductases, Old Yellow... 62 2e-08
UniRef50_Q7UMA9 Cluster: Probable NADH oxidase; n=3; Planctomyce... 62 2e-08
UniRef50_Q6AMZ5 Cluster: Related to NADH oxidase; n=1; Desulfota... 62 2e-08
UniRef50_Q11ZY3 Cluster: FAD-dependent pyridine nucleotide-disul... 62 2e-08
UniRef50_Q3AE43 Cluster: Nitrite reductase; n=1; Carboxydothermu... 62 3e-08
UniRef50_Q8WR54 Cluster: NADH oxidase; n=2; Entamoeba histolytic... 62 3e-08
UniRef50_A3H9W2 Cluster: FAD-dependent pyridine nucleotide-disul... 62 3e-08
UniRef50_Q241B3 Cluster: Pyridine nucleotide-disulphide oxidored... 62 4e-08
UniRef50_Q8TX00 Cluster: NAD(FAD)-dependent dehydrogenase; n=1; ... 62 4e-08
UniRef50_UPI000065E4E2 Cluster: Homolog of Brachydanio rerio "Pd... 61 6e-08
UniRef50_Q602Q8 Cluster: Pyridine nucleotide-disulphide oxidored... 61 6e-08
UniRef50_Q1YQY9 Cluster: Ferredoxin reductase; n=2; unclassified... 61 6e-08
UniRef50_Q02CL8 Cluster: Nitrite reductase (NAD(P)H), large subu... 61 6e-08
UniRef50_A3DBW2 Cluster: FAD-dependent pyridine nucleotide-disul... 61 6e-08
UniRef50_Q9RVN5 Cluster: NADH oxidase; n=4; Deinococci|Rep: NADH... 61 8e-08
UniRef50_Q5P0H4 Cluster: Phenylglyoxylate:acceptor oxidoreductas... 61 8e-08
UniRef50_Q0K330 Cluster: Pyridine nucleotide-disulphide oxidored... 61 8e-08
UniRef50_A6DPB5 Cluster: Nitrite reductase [NAD(P)H] large subun... 61 8e-08
UniRef50_UPI0001555C21 Cluster: PREDICTED: similar to hCG24487; ... 60 1e-07
>UniRef50_P09622 Cluster: Dihydrolipoyl dehydrogenase, mitochondrial
precursor; n=183; cellular organisms|Rep: Dihydrolipoyl
dehydrogenase, mitochondrial precursor - Homo sapiens
(Human)
Length = 509
Score = 664 bits (1641), Expect = 0.0
Identities = 321/483 (66%), Positives = 378/483 (78%), Gaps = 4/483 (0%)
Query: 18 LVRIATRQYATTH-DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCI 76
L + R YA DAD+ VIGSGPGGYVAAIKAAQLG K V +EK+ TLGGTCLNVGCI
Sbjct: 27 LSAVPLRTYADQPIDADVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCI 86
Query: 77 PSKALLHNSHLYHMAKH-DFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNK 135
PSKALL+NSH YHMA DF RGIE EV + KMME K+ AVK LTGGIA LF++NK
Sbjct: 87 PSKALLNNSHYYHMAHGTDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNK 146
Query: 136 VNLVKGVGTIVAPNKVEV-HGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGA 194
V V G G I N+V + G + ++TKNILIA+GSEVTPFPG+T DE I++STGA
Sbjct: 147 VVHVNGYGKITGKNQVTATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGA 206
Query: 195 LSLESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILS 254
LSL+ VP+KM+VIGAGVIG+ELGSV+QRLGADVTA+EFL +GGVGID E++K Q+IL
Sbjct: 207 LSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQ 266
Query: 255 KQGMKFKLGTKVLGV-KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDK 313
KQG KFKL TKV G KK I V +EAA GG EV+ CDV+L+ IGRRP+TK LGL++
Sbjct: 267 KQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEE 326
Query: 314 VGIALDDRGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNY 373
+GI LD RGRIPVN +FQT +P IYAIGDV+ GPMLAHKAEDEGI+CVEG+ G VH +Y
Sbjct: 327 LGIELDPRGRIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDY 386
Query: 374 DAIPSVIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKT 433
+ +PSVIYT PEV WVGK+EE LK+EG YKVGKFPF ANSRAKTN +T+G VK+L K+
Sbjct: 387 NCVPSVIYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKS 446
Query: 434 TDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKP 493
TD +LG HI+GPG GE++NEA LA EYGA+ ED+ARVCHAHPT +EA REANLAA GK
Sbjct: 447 TDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKS 506
Query: 494 INF 496
INF
Sbjct: 507 INF 509
>UniRef50_A0LAA4 Cluster: Dihydrolipoyl dehydrogenase; n=9; cellular
organisms|Rep: Dihydrolipoyl dehydrogenase -
Magnetococcus sp. (strain MC-1)
Length = 468
Score = 545 bits (1344), Expect = e-153
Identities = 269/456 (58%), Positives = 332/456 (72%), Gaps = 2/456 (0%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DLVVIG GPGGYVAAI+AAQLG+K ++K PTLGGTCLNVGCIPSKALL +SH A+
Sbjct: 6 DLVVIGGGPGGYVAAIRAAQLGLKTACIDKRPTLGGTCLNVGCIPSKALLQSSHQLETAQ 65
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
H G+E V + MM+ K V+GLT GIA LF+KNKV + G GTIV + V+
Sbjct: 66 HAMAAHGVEIKGVKANLTTMMQRKQEVVQGLTQGIAFLFKKNKVTHLMGSGTIVDSSHVQ 125
Query: 153 VHGEKG-VETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGV 211
V G V+T+ T+NILIASGSEV PG+ DEK II+STGAL+L+ VPKKM+VIGAGV
Sbjct: 126 VTAADGSVQTLTTENILIASGSEVATLPGLEIDEKHIISSTGALALDKVPKKMVVIGAGV 185
Query: 212 IGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKK 271
IGLELGSV++RLGA+VT +EFL I G+DGE+ KT Q+ LSKQGM FKLGTKV
Sbjct: 186 IGLELGSVWRRLGAEVTVVEFLDGILP-GMDGEIRKTAQRTLSKQGMHFKLGTKVTAASV 244
Query: 272 EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQ 331
+ +K+ +E KGG E DVVL+++GRRPYT+GLGL+ +G+ LD+RG IPV++ Q
Sbjct: 245 LKNGVKLTMEPVKGGEAEERQADVVLVAVGRRPYTQGLGLENIGVTLDERGFIPVDHDRQ 304
Query: 332 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGK 391
TT G++AIGDVI G MLAHKAE+EG E + G H NYDAIP+V+YT PE+ VG+
Sbjct: 305 TTCAGVFAIGDVIGGAMLAHKAEEEGSAVAEALAGQVAHVNYDAIPAVVYTHPEIASVGQ 364
Query: 392 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 451
+EE L G YKVGKFPF+ANSRA+ G+ EGFVK+L+ T+D ILG HIIGP G+LI
Sbjct: 365 SEESLTAAGIPYKVGKFPFMANSRARAIGDAEGFVKILAHATSDAILGAHIIGPAAGDLI 424
Query: 452 NEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 487
E VLA E +AED+AR CHAHP EA++EA LA
Sbjct: 425 AEIVLAMECDISAEDIARTCHAHPGLGEAVKEAALA 460
>UniRef50_Q67B06 Cluster: Dihydrolipoyl dehydrogenase; n=22;
Bacteria|Rep: Dihydrolipoyl dehydrogenase - Bartonella
henselae (Rochalimaea henselae)
Length = 468
Score = 520 bits (1283), Expect = e-146
Identities = 249/466 (53%), Positives = 336/466 (72%), Gaps = 5/466 (1%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+VVIG+GPGGYVAAIKAAQLG+K +EK TLGGTCLNVGCIPSKALLH S ++ +
Sbjct: 4 DVVVIGAGPGGYVAAIKAAQLGLKTAIIEKRMTLGGTCLNVGCIPSKALLHASEVFAETQ 63
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
H F+ GI + + ++MM +K V T G++ L +KNK++ G I+ ++E
Sbjct: 64 HGFETLGISIAKSKLNLEQMMAHKKAVVTANTSGVSFLMKKNKIDTFFGTAKILNAGQIE 123
Query: 153 VHGEKG-VETVNTKNILIASGSEVTPFPGVT--FDEKQIITSTGALSLESVPKKMLVIGA 209
V G +T+ TKNI+IA+GSE + PGV DEK I++STGAL+LE VP +M+V+GA
Sbjct: 124 VVARDGNKQTIETKNIIIATGSESSGIPGVNVEIDEKVIVSSTGALALEKVPTRMIVVGA 183
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
GVIG ELGSV+ RLGA VT IE+L + G +DGEV++ QKI+ KQG++FK+G KV +
Sbjct: 184 GVIGSELGSVWSRLGAKVTIIEYLNKVLG-SMDGEVSRQFQKIMEKQGIEFKIGAKVTAI 242
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
+ GS +V EA KGG E L+ DVVLI+ GR PYT+GLGL++ G+ LD+RG I ++
Sbjct: 243 TQSGSVAQVTFEAVKGGPSETLEADVVLIATGRFPYTEGLGLEEAGVQLDERGFITIDAH 302
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWV 389
+QT +PG+YAIGDV+ GPMLAHKAE+EG+ E + G H N+D IPSV+YT PE+ V
Sbjct: 303 WQTNIPGVYAIGDVVKGPMLAHKAEEEGVAVAEILAGQKGHVNFDVIPSVVYTQPEIASV 362
Query: 390 GKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGE 449
GKTEE+LK G Y VGKFPF+AN RA+ +++GFVK+L+DK TD +LG HI+G G GE
Sbjct: 363 GKTEEELKAAGIDYNVGKFPFMANGRARAMQKSDGFVKILADKKTDRVLGGHILGFGAGE 422
Query: 450 LINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
+I+E + E+G ++ED+ R CHAHPT +EA+REA LA ++ KP++
Sbjct: 423 MIHEIAVLMEFGGSSEDLGRCCHAHPTLSEAVREAALATFA-KPLH 467
>UniRef50_Q1KSF4 Cluster: Dihydrolipoyl dehydrogenase; n=25;
cellular organisms|Rep: Dihydrolipoyl dehydrogenase -
Toxoplasma gondii
Length = 519
Score = 492 bits (1214), Expect = e-138
Identities = 255/469 (54%), Positives = 330/469 (70%), Gaps = 8/469 (1%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+VV+G GPGGYVAAIKAAQLG+K VEK TLGGTCLNVGCIPSKA+L+ S+ Y A+
Sbjct: 51 DVVVVGGGPGGYVAAIKAAQLGLKTACVEKRGTLGGTCLNVGCIPSKAVLNISNKYVDAR 110
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
F++ GI+ ++ D KM + K V LT GI LF++N V+ G G + N VE
Sbjct: 111 DHFERLGIKIDGLSIDIDKMQKQKQKVVSTLTQGIEHLFRRNGVDYYVGEGKLTDSNSVE 170
Query: 153 V--HGEKGVETVNTKNILIASGSEVTPFPG--VTFDEKQIITSTGALSLESVPKKMLVIG 208
V +G+ + ++ +I++A+GSE +P PG V DEK II+STGAL+L+ VPK+M VIG
Sbjct: 171 VTPNGKSEKQRLDAGHIILATGSEASPLPGNVVPIDEKVIISSTGALALDKVPKRMAVIG 230
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
GVIGLELGSV++ LGA+VT +EFL + +DGEVAK QK + K G+KF+LGTKV+G
Sbjct: 231 GGVIGLELGSVWRNLGAEVTVVEFLDRLLPP-VDGEVAKAFQKEMEKTGIKFQLGTKVVG 289
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
S+ + VE AKGGN ++ DVVL+++GRRPYTK LGL+++GI D GR+ V++
Sbjct: 290 ADVRESSATLHVEPAKGGNPFDMEADVVLVAVGRRPYTKNLGLEELGIETDRVGRVVVDD 349
Query: 329 KFQT-TVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPV-HFNYDAIPSVIYTSPEV 386
+F P I AIGD+I GPMLAHKAE+EGI CVE I G+ H NY+ IPSVIYT PE+
Sbjct: 350 RFCVPNYPNIRAIGDLIRGPMLAHKAEEEGIACVEMIAGVGEGHVNYETIPSVIYTHPEI 409
Query: 387 GWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPG 446
VGKTEE+LK G +Y G FPF ANSRA+ N GFVKVL+ K +D +LG I+GP
Sbjct: 410 AGVGKTEEELKANGVSYNKGTFPFAANSRARANDVATGFVKVLAHKDSDKLLGAWIMGPE 469
Query: 447 GGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
GELI + VL EYGAAAED+ R C +HPT +EA++EA +A Y KPI+
Sbjct: 470 AGELIGQLVLGMEYGAAAEDLGRTCVSHPTLSEAVKEACMACYD-KPIH 517
>UniRef50_Q8F6S8 Cluster: Dihydrolipoyl dehydrogenase; n=30;
Bacteria|Rep: Dihydrolipoyl dehydrogenase - Leptospira
interrogans
Length = 467
Score = 467 bits (1151), Expect = e-130
Identities = 228/456 (50%), Positives = 308/456 (67%), Gaps = 3/456 (0%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+VVIG+GPGGYV AI+ AQLG K +EK TLGGTCLNVGCIPSKALL +S YH
Sbjct: 6 DVVVIGAGPGGYVCAIRCAQLGFKTAIIEKRKTLGGTCLNVGCIPSKALLDSSEEYHKTL 65
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
H + GI G+V D K+M K VK +T G+ L KNK+ +G G +++ KVE
Sbjct: 66 HKLEVHGISVGKVDLDLNKLMNRKDQIVKEVTDGVDFLMNKNKIKRYEGFGKVLSAGKVE 125
Query: 153 VHGEKGV-ETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGV 211
V G ET++ K+I++A+GS PG+T D K IITS A+ + +PKKM++IGAGV
Sbjct: 126 VAFNDGKKETLSAKHIVVATGSVPIDIPGLTVDGKNIITSDHAIDVRKLPKKMIIIGAGV 185
Query: 212 IGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKK 271
IGLELGSV+ RLG VT +EFL + +D ++ L++ L+ QGM+F KV G
Sbjct: 186 IGLELGSVWGRLGTSVTVVEFLPGLIS-NVDRQMGSLLERSLTSQGMEFLFEHKVKGAAT 244
Query: 272 EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQ 331
+ +KV +E +KG +K+ L+ DVVL+++GRRP+ +G+GL++ G+A R RI V+ F+
Sbjct: 245 TKNGVKVQIEDSKGESKD-LEADVVLVAVGRRPFLEGVGLEEAGVAFTQRKRIQVDAHFK 303
Query: 332 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGK 391
T+VPGIYAIGD I GPMLAHKAE+EG+ E + G H NY+A+P VIYT PE+ WVGK
Sbjct: 304 TSVPGIYAIGDAIDGPMLAHKAEEEGVALAELLAGQSGHVNYNAVPYVIYTWPEMAWVGK 363
Query: 392 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 451
EE+LK G YKVGK F N+R+K E EG VK+L+DK TD +LG + GP +++
Sbjct: 364 GEEELKAAGIEYKVGKSLFRPNARSKAMNEAEGQVKILADKKTDKLLGAFVFGPRASDMV 423
Query: 452 NEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 487
E +A E+GA+AED+AR HAHPT +E ++EA +A
Sbjct: 424 AELAVAMEFGASAEDIARSFHAHPTLSEVIKEAAMA 459
>UniRef50_Q5FGZ4 Cluster: Dihydrolipoyl dehydrogenase; n=11;
Rickettsiales|Rep: Dihydrolipoyl dehydrogenase -
Ehrlichia ruminantium (strain Gardel)
Length = 474
Score = 456 bits (1123), Expect = e-127
Identities = 231/461 (50%), Positives = 302/461 (65%), Gaps = 6/461 (1%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+VVIG GPGGY AI++AQLG+KV V+K+ LGGTCL VGCIPSKALLH SH Y+ K
Sbjct: 14 DVVVIGGGPGGYKCAIRSAQLGLKVACVDKNEILGGTCLRVGCIPSKALLHFSHEYYHIK 73
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK-- 150
+ + GI ++F+ K+M +K + L GI LF NK++ + GVG I + N
Sbjct: 74 NHLDEVGITCNSLSFNLDKIMSFKNKNITELGNGINYLFASNKIDRLCGVGKIRSINSNN 133
Query: 151 --VEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
+ V G G E + K ++IA+GSEV FPG+ DE +++ST ALS + VPKK++V+G
Sbjct: 134 FDITVTGNNGEEKITAKYVVIATGSEVASFPGIEIDENNVVSSTAALSFKEVPKKLVVVG 193
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
AG IGLE+ SV+ R G++VT +EFL I +D +++K L L KQG+ FKL TKV
Sbjct: 194 AGAIGLEMSSVWSRFGSEVTVVEFLDKIAP-SMDIDISKALLASLKKQGINFKLSTKVTS 252
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
+ K + + +E+ K G E+++ + VLISIGR PYT GL +D+ I D RG I VNN
Sbjct: 253 IDKSSDNLTIHLESVKDGKSEIIEAEKVLISIGRIPYTDGL-IDQNCIECDSRGFIKVNN 311
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGW 388
K++T +PGI+AIGDVI G MLAHKAE+EGI E I G H +YD IPSVIYT P V
Sbjct: 312 KYETNIPGIFAIGDVIGGAMLAHKAEEEGIAVAELIAGNIPHVDYDIIPSVIYTHPAVAS 371
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
+GKTEE LK AY VGK F ANSR+K EGFVKVL+ K + ILG HIIG
Sbjct: 372 IGKTEESLKNINYAYNVGKSNFSANSRSKITNNGEGFVKVLTSKENNAILGVHIIGAYAD 431
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAY 489
+INEA +A Y A++EDV R+ H+HP EA ++A AAY
Sbjct: 432 TIINEAAIAMAYRASSEDVFRISHSHPDVNEAFKDACEAAY 472
>UniRef50_P52992 Cluster: Dihydrolipoyl dehydrogenase; n=34;
root|Rep: Dihydrolipoyl dehydrogenase - Ralstonia
eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier
337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM
428 / Stanier337))
Length = 474
Score = 452 bits (1114), Expect = e-125
Identities = 233/465 (50%), Positives = 301/465 (64%), Gaps = 14/465 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDP--------TLGGTCLNVGCIPSKALLHN 84
D++VIG+GPGGY+AAI+A QLG+ V E +P LGGTCLNVGCIPSKALL +
Sbjct: 6 DVLVIGAGPGGYIAAIRAGQLGLNVACCEGNPYDDPKGEARLGGTCLNVGCIPSKALLAS 65
Query: 85 SHLYHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGT 144
S + +H GI G+V D KM++ K + V +T GI LF+KNKV L+KG G
Sbjct: 66 SEEFENVQHHLGDHGITVGDVKVDVAKMLKRKDDIVGKMTKGIEFLFRKNKVTLLKGYGK 125
Query: 145 IVAPNKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKM 204
V + + E V K ++IA+GS+ PG+ D + + GAL +VPKK+
Sbjct: 126 FVGKSAEGFQVDVAGEVVTAKQVIIATGSKARHLPGIKVDNDLVSDNEGALKFPAVPKKL 185
Query: 205 LVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGT 264
VIGAGVIGLELGSV++RLG+DVT +E L + G +G VAK QK L+KQG+KF LG
Sbjct: 186 GVIGAGVIGLELGSVWRRLGSDVTVLEALPAFLGAADEG-VAKEAQKQLTKQGLKFSLGV 244
Query: 265 KVLGVK--KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRG 322
V V K G T+K K G + L+ D +++S+GR P T LGLD VG+A D RG
Sbjct: 245 NVNEVTTGKNGVTVKY---TDKDGKAQTLEVDRLIVSVGRVPNTDNLGLDAVGLAADQRG 301
Query: 323 RIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYT 382
I V++ T VPG++AIGDV+ GPMLAHKAEDEG+ E I G H +Y+ +P VIYT
Sbjct: 302 FIEVDDHCATKVPGLWAIGDVVRGPMLAHKAEDEGVAVAERIAGQKPHIDYNCVPWVIYT 361
Query: 383 SPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHI 442
PE+ WVGKTE LK EGR YK G+FPF+AN RA G +GFVK+L+D TD ILG HI
Sbjct: 362 FPEIAWVGKTEAQLKAEGREYKAGQFPFMANGRALGMGHADGFVKMLADAKTDEILGVHI 421
Query: 443 IGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 487
+ +LI EAV+A E+ AA+ED+ RVCH HP+ +E +REA LA
Sbjct: 422 VAANASDLIAEAVVAMEFKAASEDIGRVCHPHPSMSEVMREAALA 466
>UniRef50_P14218 Cluster: Dihydrolipoyl dehydrogenase; n=65;
cellular organisms|Rep: Dihydrolipoyl dehydrogenase -
Pseudomonas fluorescens
Length = 478
Score = 440 bits (1084), Expect = e-122
Identities = 227/462 (49%), Positives = 297/462 (64%), Gaps = 10/462 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEK------DPTLGGTCLNVGCIPSKALLHNSH 86
D+VVIG+GPGGYVAAI+AAQLG+K +EK LGGTCLNVGCIPSKALL +S+
Sbjct: 6 DVVVIGAGPGGYVAAIRAAQLGLKTACIEKYIGKEGKVALGGTCLNVGCIPSKALLDSSY 65
Query: 87 LYHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIV 146
YH AK FK GIE VT D M+ KAN VK LTGGIA LF+ N V +G G ++
Sbjct: 66 KYHEAKEAFKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKANGVTSFEGHGKLL 125
Query: 147 APNKVEVHGEKG-VETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKML 205
A +VEV G G + + +N++IASGS P + I+ STGAL ++VPKK+
Sbjct: 126 ANKQVEVTGLDGKTQVLEAENVIIASGSRPVEIPPAPLSDDIIVDSTGALEFQAVPKKLG 185
Query: 206 VIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTK 265
VIGAGVIGLELGSV+ RLGA+VT +E L D ++AK K+L+KQG+ +LG +
Sbjct: 186 VIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAA-DEQIAKEALKVLTKQGLNIRLGAR 244
Query: 266 VLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIP 325
V + + + V A G KE D +++++GRRP T L G+ LD+RG I
Sbjct: 245 VTASEVKKKQVTVTFTDANGEQKETFD--KLIVAVGRRPVTTDLLAADSGVTLDERGFIY 302
Query: 326 VNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPE 385
V++ +T+VPG++AIGDV+ G MLAHKA +EG++ E I G NYD IPSVIYT PE
Sbjct: 303 VDDHCKTSVPGVFAIGDVVRGAMLAHKASEEGVMVAERIAGHKAQMNYDLIPSVIYTHPE 362
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGP 445
+ WVGKTE+ LK EG VG FPF A+ RA +T G VKV++D TD +LG H+IGP
Sbjct: 363 IAWVGKTEQTLKAEGVEVNVGTFPFAASGRAMAANDTTGLVKVIADAKTDRVLGVHVIGP 422
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 487
EL+ + + E+G +AED+ + +HPT +EAL EA LA
Sbjct: 423 SAAELVQQGAIGMEFGTSAEDLGMMVFSHPTLSEALHEAALA 464
>UniRef50_Q11NC9 Cluster: Dihydrolipoyl dehydrogenase; n=4;
Alphaproteobacteria|Rep: Dihydrolipoyl dehydrogenase -
Mesorhizobium sp. (strain BNC1)
Length = 462
Score = 436 bits (1073), Expect = e-121
Identities = 219/466 (46%), Positives = 302/466 (64%), Gaps = 7/466 (1%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
D DL+VIG+GPGGYVAA++AAQ GM+V +++ T GGTCLNVGCIPSKALL ++ +
Sbjct: 3 DFDLIVIGAGPGGYVAALRAAQAGMRVACIDERATAGGTCLNVGCIPSKALLSSTEHWAG 62
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
K GIET D +MM K V LT IA LF K V + G +I AP +
Sbjct: 63 LK-SLADHGIETEAARVDLSRMMARKDKVVSDLTKSIAFLFNKAGVEFIHGRASIAAPGR 121
Query: 151 VEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
V V GV +++++ILIA+GS P V FDEK +++STGALSL VP +++V+GAG
Sbjct: 122 VTV----GVREISSQHILIATGSAPAVLPNVPFDEKLVLSSTGALSLAKVPDRLVVVGAG 177
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
VIGLE+G ++ RLGA VT +E+L I G+DGE AK Q+I ++QG+ F L V V
Sbjct: 178 VIGLEIGQIWSRLGAKVTVVEYLDRILP-GMDGETAKNAQRIFARQGIGFMLNAAVEAVV 236
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
G T ++ +++ G E L D VL++IGR+P+T GLGL+ + + D RG I V+ +F
Sbjct: 237 DNGETAEIKIKSRASGKVEKLQADAVLVAIGRKPHTGGLGLEALRVRRDARGFIEVDEQF 296
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMP-VHFNYDAIPSVIYTSPEVGWV 389
+T+VPGI AIGDV+ GPMLAHKAE++ + C++ + G P +Y +P V+YT+PE+ V
Sbjct: 297 RTSVPGILAIGDVVPGPMLAHKAEEDAVACIDALAGKPHCAPDYGLVPGVVYTTPEIAGV 356
Query: 390 GKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGE 449
G TE+D GRA +GK FLAN RA+ G T+GF KV++ T +LG HI+G G GE
Sbjct: 357 GLTEDDASAAGRAVLIGKASFLANGRARAIGTTDGFAKVIACAETGKLLGAHILGHGAGE 416
Query: 450 LINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
L+ E VLA +GA+ DVA HAHP EA++EA L+ + ++
Sbjct: 417 LLQELVLALRFGASLNDVAGTSHAHPGMGEAVKEACLSVLDARSLD 462
>UniRef50_Q74AD0 Cluster: Dihydrolipoyl dehydrogenase; n=17;
Proteobacteria|Rep: Dihydrolipoyl dehydrogenase -
Geobacter sulfurreducens
Length = 472
Score = 428 bits (1055), Expect = e-118
Identities = 219/460 (47%), Positives = 298/460 (64%), Gaps = 9/460 (1%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL+VIG+GPGGYVAAI+AAQLGM V E+ TLGG CLN GCIPSKALL +S + A+
Sbjct: 7 DLIVIGAGPGGYVAAIRAAQLGMTVAVAEQRETLGGVCLNEGCIPSKALLDSSEFFAQAR 66
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPN--- 149
F GI D +MM K + VK LT GIA LF+KN++ +KG + N
Sbjct: 67 DGFAGHGILIDPPRLDLARMMARKDDVVKKLTDGIAYLFKKNRITWLKGTARLAGRNGDL 126
Query: 150 -KVEV--HGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLV 206
+VEV +G + +L+A+GSE P PG+ FD + ++++ AL+ + VP+ +LV
Sbjct: 127 LRVEVGGNGTAPAHLLEAGKVLLATGSEAVPVPGLAFDGETVVSAREALAFDRVPEHLLV 186
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
+GAG IGLELGSV++RLG+ VT +E L DG+VA L + L KQG+ F++ T+V
Sbjct: 187 VGAGYIGLELGSVWRRLGSQVTVVEVLAK-PLPATDGQVADALVRSLKKQGISFRMETRV 245
Query: 267 LGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPV 326
G++K T V VE++ GG ++ + CD VL++ GRRP GLGL+ +A++ GRI V
Sbjct: 246 TGIEKREGTAVVTVESSAGG-RDAIACDRVLVAAGRRPVMAGLGLEPFNLAMEG-GRIRV 303
Query: 327 NNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEV 386
++ + T+ PGIYAIGD+IHGPMLAHKA EG V E + G +Y+ IP ++YT PE
Sbjct: 304 DDNYLTSAPGIYAIGDLIHGPMLAHKAMAEGEVFAERLTGEASVVDYEYIPGIVYTWPEA 363
Query: 387 GWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPG 446
VG TEE LK++G Y G+F F+AN RA+ GETEGFVK+L+ T +LG H++GP
Sbjct: 364 AGVGLTEEQLKEQGIPYAAGRFNFMANGRARCMGETEGFVKILAKPDTGRVLGIHVVGPR 423
Query: 447 GGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANL 486
+LI EAV YG +A D+A HAHPT AEA++EA L
Sbjct: 424 ASDLIAEAVTVMTYGGSAADIAMTFHAHPTLAEAMKEAAL 463
>UniRef50_Q7UVC8 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Bacteria|Rep: Dihydrolipoyl dehydrogenase -
Rhodopirellula baltica
Length = 474
Score = 421 bits (1036), Expect = e-116
Identities = 215/460 (46%), Positives = 288/460 (62%), Gaps = 6/460 (1%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
+LV++G GP GYVAAI+AAQLG+ V ++ +P GGTC+ VGCIPSKALL +SHLY A+
Sbjct: 7 ELVILGGGPAGYVAAIRAAQLGIDVACIDDNPRFGGTCVRVGCIPSKALLESSHLYEEAQ 66
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
H F G+ V D MM+ K V+ LTGGI MLF + V G G + + +E
Sbjct: 67 HKFADHGLNVSNVEVDLDVMMKRKEKIVESLTGGIDMLFDRRGVTAYHGRGRLRDVDSIE 126
Query: 153 VHGEKGVET-----VNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVI 207
+ +G V I++ GS P V D +I ST ALS VP++++VI
Sbjct: 127 ITPSEGAAEDQPTLVTADQIMLCPGSVPAQLPFVEEDGDRIGNSTTALSFPEVPEELVVI 186
Query: 208 GAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVL 267
G G IGLELGSV+ RLG++V +E I G+D E+A + KQGM + GT V
Sbjct: 187 GGGYIGLELGSVWNRLGSNVIVLEAFDRIMP-GLDKEMATLAHRSFKKQGMDIRTGTFVA 245
Query: 268 GVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVN 327
K + K N E + CD VL++ GR P TK +GL++ G+ LD+RG I VN
Sbjct: 246 SAKVDPKPGDKKPCVIKIKNGETIRCDRVLLATGRAPATKSMGLEEAGVKLDERGFIQVN 305
Query: 328 NKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVG 387
++F+T+V GIYAIGD I G MLAHKA +EGIVCVE + G+ NY+ IP++++T PE+
Sbjct: 306 HQFETSVTGIYAIGDCIGGAMLAHKAMEEGIVCVEQMAGIASEMNYEVIPAIVFTHPEIA 365
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VGKTEE+LK+ G Y G P AN RA+T G+ +G VK+L+D TD +LG HIIGP
Sbjct: 366 MVGKTEEELKEAGIEYNKGVCPLGANGRARTLGDIDGRVKILADAATDRVLGVHIIGPRA 425
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 487
G++I EA A E+GA++ED+AR CHAHPT +EA+ EA LA
Sbjct: 426 GDMIAEAAAAMEFGASSEDIARTCHAHPTLSEAVHEAALA 465
>UniRef50_Q6MC87 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Candidatus Protochlamydia amoebophila UWE25|Rep:
Dihydrolipoyl dehydrogenase - Protochlamydia amoebophila
(strain UWE25)
Length = 465
Score = 413 bits (1016), Expect = e-114
Identities = 214/463 (46%), Positives = 301/463 (65%), Gaps = 4/463 (0%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL V+G+GPGGYVAAI+AAQ+G+K + ++K TLGGTCLNVGCIPSK LLH++ LY K
Sbjct: 6 DLAVVGAGPGGYVAAIRAAQMGLKTICIDKRETLGGTCLNVGCIPSKTLLHSTDLYSTLK 65
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
++ IE ++ +F K+ME K N VKGL GIA+LF+KN V +KG + + ++
Sbjct: 66 QHGLEQAIEVSDLKVNFTKLMERKRNVVKGLIEGIALLFKKNGVIYLKGEAQFLDAHTLQ 125
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVI 212
V ++ + IL+A+GSE T P + FDEK I++STGAL+L +VP ++LVIG GVI
Sbjct: 126 VKNGTHIDEIKANYILLATGSESTSLPHLPFDEKNIVSSTGALNLATVPPRLLVIGGGVI 185
Query: 213 GLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKE 272
G+EL SVY RLG+ VT IE + +D ++K L +IL KQG++ KL TK++ +
Sbjct: 186 GVELASVYNRLGSSVTIIEMSDRL-CPAMDIALSKYLFQILKKQGIEIKLSTKMMTAVLQ 244
Query: 273 GSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQT 332
+ + +E + + + +VVL+++GRRPYT+GL LDKVGI +D +G IPV+ F+T
Sbjct: 245 PNETILTIE--QNEQLQNISGEVVLVAVGRRPYTQGLALDKVGIQIDKKGFIPVDGFFRT 302
Query: 333 TVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGKT 392
+ P I+AIGD+I G MLAH+A EGI VE +KG NY AIP+V+YT+PEV VG T
Sbjct: 303 SQPHIFAIGDLIEGVMLAHRASQEGITVVEWLKGERQSINYLAIPNVVYTNPEVASVGLT 362
Query: 393 EEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELIN 452
E++ + G G F NSRA+ E EGFVK++ +K + +LG HIIG ELI
Sbjct: 363 EQEASESGLTLLTGTTYFRGNSRARCTDEIEGFVKLIGEKKSGRLLGMHIIGAHASELIA 422
Query: 453 EAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
LA + +D+A AHPT +E ++EA L A GK ++
Sbjct: 423 VGTLAIQKQINLKDLAETVQAHPTLSETIKEAALQAL-GKAVH 464
>UniRef50_Q4N0C2 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Theileria|Rep: Dihydrolipoyl dehydrogenase - Theileria
parva
Length = 499
Score = 395 bits (972), Expect = e-108
Identities = 225/504 (44%), Positives = 320/504 (63%), Gaps = 37/504 (7%)
Query: 17 SLVRIATRQYATTHDA-DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGC 75
SL+ I RQ++T+ DL+V+G+GPGGY AIKAAQ G+KV VEK PTLGGTCLN GC
Sbjct: 9 SLLNIK-RQFSTSSSKYDLLVLGAGPGGYTMAIKAAQHGLKVGVVEKRPTLGGTCLNCGC 67
Query: 76 IPSKALLHNSHLYHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNK 135
IPSK+LL+ SHLYH+ K G+ + D KMME K + ++ L GI LF+KNK
Sbjct: 68 IPSKSLLNTSHLYHLMKKGV--NGLRITGLETDVGKMMEEKDSVMRTLNMGIFGLFKKNK 125
Query: 136 VNLVKGVGTIVAPNKVEVHGEKGVETVNTKNILIASGSEVTPFP--GVTFDEKQIITSTG 193
++ ++G + N+V V G + + +++A+GSEV PFP + D K ++ST
Sbjct: 126 IDYIQGTACFKSQNEVTV----GSKVLLADKVVVATGSEVRPFPSESLKVDGKYFLSSTE 181
Query: 194 ALSLESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKIL 253
L L+ VP ++LVIGAG IGLEL SV+ RLG+ V EF I V +D +V T++KIL
Sbjct: 182 TLCLDKVPNRLLVIGAGAIGLELASVWSRLGSKVDIFEFNNQICSV-MDTDVCVTMRKIL 240
Query: 254 SKQGMKFKLGTKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDK 313
KQG+ GTKVL K +T+ + E+ G + D VL+++GR PYT+GLG+DK
Sbjct: 241 EKQGLNIHTGTKVLNAKVTNNTVTLTTESE--GKEMSYVGDKVLVAMGRVPYTEGLGIDK 298
Query: 314 VGIALDDRGRIPVNNKFQ---------TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI 364
+G+ L D G++P +N + + V +YAIGDV +GPMLAHKAE++G++ + I
Sbjct: 299 LGVTL-DYGKVPTDNNLRVLKDPKDPNSVVENVYAIGDVTYGPMLAHKAEEDGLIALGHI 357
Query: 365 KGMP-VHFNY-----------DAIPSVIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLA 412
G VH + IPSVIYT PE+ VG+TE++L+K G YK FPF+A
Sbjct: 358 LGKSFVHHPQGVTLGSVQVVPNVIPSVIYTEPEIAGVGETEQNLQKLGVKYKKSVFPFMA 417
Query: 413 NSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCH 472
NSRAK E++GF+K+LS + + +LG +IGP E+I+ LA YGA++EDV R+C
Sbjct: 418 NSRAKIYNESDGFIKLLSTE-ENKLLGAWMIGPHVSEMIHTTALAITYGASSEDVTRMCF 476
Query: 473 AHPTCAEALREANLAAYSGKPINF 496
AHP+ +EA++E++L + KP++F
Sbjct: 477 AHPSLSEAIKESSLGIHF-KPLHF 499
>UniRef50_P21880 Cluster: Dihydrolipoyl dehydrogenase; n=27;
Bacilli|Rep: Dihydrolipoyl dehydrogenase - Bacillus
subtilis
Length = 470
Score = 386 bits (950), Expect = e-106
Identities = 206/466 (44%), Positives = 282/466 (60%), Gaps = 8/466 (1%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
+ D +VIG+GPGGYVAAI+AAQLG KV VEK TLGG CLNVGCIPSKAL++ H Y
Sbjct: 9 ETDTLVIGAGPGGYVAAIRAAQLGQKVTVVEK-ATLGGVCLNVGCIPSKALINAGHRYEN 67
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
AKH GI VT DF K+ E+KA+ V LTGG+A L + NKV++VKG V N
Sbjct: 68 AKHS-DDMGITAENVTVDFTKVQEWKASVVNKLTGGVAGLLKGNKVDVVKGEAYFVDSNS 126
Query: 151 VEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
V V E +T KN +IA+GS P + E+ ++ STGAL+L+ +PKK++VIG G
Sbjct: 127 VRVMDENSAQTYTFKNAIIATGSRPIELPNFKYSER-VLNSTGALALKEIPKKLVVIGGG 185
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQG-MKFKLGTKVLGV 269
IG ELG+ Y G ++ +E I G + +++ + + L K+G ++ GV
Sbjct: 186 YIGTELGTAYANFGTELVILEGGDEILP-GFEKQMSSLVTRRLKKKGNVEIHTNAMAKGV 244
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
++ + V E G ++ +D D VLI++GRRP T LGL++VGI + DRG + + +
Sbjct: 245 EERPDGVTVTFEVK--GEEKTVDADYVLITVGRRPNTDELGLEQVGIEMTDRGIVKTDKQ 302
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWV 389
+T VP IYAIGD+I GP LAHKA EG + E I G P +Y IP+V+++ PE+ V
Sbjct: 303 CRTNVPNIYAIGDIIEGPPLAHKASYEGKIAAEAIAGEPAEIDYLGIPAVVFSEPELASV 362
Query: 390 GKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGE 449
G TE K+EG KFPF AN RA + ET+GF+K+++ K +++G I G +
Sbjct: 363 GYTEAQAKEEGLDIVAAKFPFAANGRALSLNETDGFMKLITRKEDGLVIGAQIAGASASD 422
Query: 450 LINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
+I+E LA E G AED+A HAHPT E EA A G PI+
Sbjct: 423 MISELSLAIEGGMTAEDIAMTIHAHPTLGEITMEAAEVAI-GSPIH 467
>UniRef50_Q6MPR7 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Deltaproteobacteria|Rep: Dihydrolipoyl dehydrogenase -
Bdellovibrio bacteriovorus
Length = 473
Score = 382 bits (939), Expect = e-104
Identities = 192/454 (42%), Positives = 283/454 (62%), Gaps = 5/454 (1%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+VVIG+GPGGYVAAI++AQLG K +E++ LGG CLNVGCIPSKA++ +HL H A+
Sbjct: 5 DVVVIGAGPGGYVAAIRSAQLGFKTAVIERE-FLGGVCLNVGCIPSKAMITATHLLHKAQ 63
Query: 93 HDFKQRGIET-GEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
H+FK+ G+ G + D K+++++K + ++GG+ L + V ++KG + ++
Sbjct: 64 HNFKEMGLNIKGGIDVDMKQLVKWKQSVSDKMSGGVNQLLKGYGVTIIKGDAEFKSSKEI 123
Query: 152 EVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGV 211
V G E+V K ++A+GS PG FDEK I +STGAL+ +++PK++ VIG G
Sbjct: 124 SVKSSAGTESVQAKYFVVATGSRPIEIPGFKFDEKDICSSTGALAFDTIPKRVAVIGGGY 183
Query: 212 IGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKK 271
IGLE+ S ++LG +VT IE +++ +D + A+ + + L+K G+ G K G KK
Sbjct: 184 IGLEISSYLRKLGTEVTVIEAQSALLAGVVDPDCAQIVTRKLTKAGVNVLYGAKAKGQKK 243
Query: 272 EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQ 331
+V VE G EV+ CD +L+++GRRP L GI +D+RG + V+ + +
Sbjct: 244 VKDGYEVTVEI--NGKDEVVKCDKILVTVGRRPNGDQANLKAAGIQVDERGFVKVDAQRR 301
Query: 332 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGK 391
T V I+AIGD+ PMLAHKA EG++ E I G ++ +P+V++T PE+ G
Sbjct: 302 TNVSNIFAIGDIAGQPMLAHKASHEGVLVAEVIAGHNRVYDAKTVPAVVFTDPEIAAAGM 361
Query: 392 TEEDLKKEGRA-YKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGEL 450
TE + K +G + KFPF AN RA + ET+GFVK+++DK T V+LG HI+GP L
Sbjct: 362 TEAEAKAKGHTDLLISKFPFAANGRAVSMMETDGFVKMIADKKTHVLLGVHIVGPEASNL 421
Query: 451 INEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
I+EAVLA E GA ED+A H HPT E + EA
Sbjct: 422 ISEAVLAIEMGARIEDLALSIHPHPTLGETMMEA 455
>UniRef50_Q9RRW5 Cluster: Dihydrolipoyl dehydrogenase; n=4;
Deinococci|Rep: Dihydrolipoyl dehydrogenase -
Deinococcus radiodurans
Length = 467
Score = 380 bits (936), Expect = e-104
Identities = 198/460 (43%), Positives = 285/460 (61%), Gaps = 8/460 (1%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
D D++VIG+GPGGY AAI+A+QLG+K VE+ +GG CLN+GCIP+KALLH +
Sbjct: 6 DYDVLVIGAGPGGYHAAIRASQLGLKTACVERG-AVGGVCLNIGCIPTKALLHAAETMQA 64
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
+KH + G+ D ++ +K + VK LTGG++ LF+ NKV L+ G + V +
Sbjct: 65 SKHA-AEFGLTFSGQALDIARLNGWKDSIVKKLTGGVSGLFKANKVTLLTGQASFVDDHT 123
Query: 151 VEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSL-ESVPKKMLVIGA 209
V+V G +T NI+IA+GS+ PG+ D++QI+ STGAL + + VP +ML +G
Sbjct: 124 VQV----GDKTYTAANIIIATGSDPAKLPGLEVDQQQIVDSTGALVMPDPVPARMLCVGG 179
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
GVIG E VY LG+ V IEFL S+ G D + K KI+S+QG++ K
Sbjct: 180 GVIGFEFAQVYNNLGSQVKIIEFLPSVIP-GADADAVKEFSKIMSRQGIEIVTQMKANRA 238
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
+K+ + V++E K G K D VL+++GRRP T GL ++ G+ + +RG IP + +
Sbjct: 239 EKKSDGVHVELENVKTGEKTTEVFDRVLVAVGRRPRTDGLNPEQAGVTVTERGFIPADKQ 298
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWV 389
+T VP I++IGDV PMLAHKA EG+V E I G P + AIP V+YT+PE+ WV
Sbjct: 299 QRTNVPHIFSIGDVAGNPMLAHKAMKEGLVAAEVIAGKPAEQDAVAIPGVVYTNPELAWV 358
Query: 390 GKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGE 449
G TE + +++G K G FP A+ RA T TEGFVK++ +K TD++LG HI+ P +
Sbjct: 359 GLTEAEAQEKGYEVKTGVFPMSASGRAMTLQATEGFVKMVVEKDTDLLLGVHIVAPHASD 418
Query: 450 LINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAY 489
++ EA LA E A A D++ HAHPT E++ EA A++
Sbjct: 419 MLAEAGLALEMAATATDISLTIHAHPTLGESILEAAEASH 458
>UniRef50_P0A0E8 Cluster: Dihydrolipoyl dehydrogenase; n=46;
Bacilli|Rep: Dihydrolipoyl dehydrogenase -
Staphylococcus aureus
Length = 468
Score = 379 bits (933), Expect = e-104
Identities = 198/465 (42%), Positives = 288/465 (61%), Gaps = 7/465 (1%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
+ D +VIG+GPGGYVAAI+AAQLG KV VEK LGG CLNVGCIPSKALLH SH +
Sbjct: 9 ETDTIVIGAGPGGYVAAIRAAQLGQKVTIVEKG-NLGGVCLNVGCIPSKALLHASHRFVE 67
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
A+H + G+ V+ +F+K+ E+K++ V LTGG+ L + NKVN+VKG V N
Sbjct: 68 AQHS-ENLGVIAESVSLNFQKVQEFKSSVVNKLTGGVEGLLKGNKVNIVKGEAYFVDNNS 126
Query: 151 VEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
+ V EK +T N KN +IA+GS P F K++I STGAL+L+ VP K++V+G G
Sbjct: 127 LRVMDEKSAQTYNFKNAIIATGSRPIEIPNFKFG-KRVIDSTGALNLQEVPGKLVVVGGG 185
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
IG ELG+ + G++VT +E I G G + ++ + ++K + ++G++ +
Sbjct: 186 YIGSELGTAFANFGSEVTILEGAKDILG-GFEKQMTQPVKKGMKEKGVEIVTEAMAKSAE 244
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
+ + +KV EA G ++ ++ D VL+++GRRP T LGL+++G+ DRG + V+ +
Sbjct: 245 ETDNGVKVTYEAK--GEEKTIEADYVLVTVGRRPNTDELGLEELGVKFADRGLLEVDKQS 302
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVG 390
+T++ IYAIGD++ G LAHKA E V E I G +Y +P+V +T PE+ VG
Sbjct: 303 RTSISNIYAIGDIVPGLPLAHKASYEAKVAAEAIDGQAAEVDYIGMPAVCFTEPELATVG 362
Query: 391 KTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGEL 450
+E K+EG A K KFP+ AN RA + +T GFVK+++ K D ++G ++G G ++
Sbjct: 363 YSEAQAKEEGLAIKASKFPYAANGRALSLDDTNGFVKLITLKEDDTLIGAQVVGTGASDI 422
Query: 451 INEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
I+E LA E G AED+A HAHPT E EA A G PI+
Sbjct: 423 ISELGLAIEAGMNAEDIALTIHAHPTLGEMTMEAAEKAI-GYPIH 466
>UniRef50_Q2RHM5 Cluster: Dihydrolipoyl dehydrogenase; n=4;
Clostridia|Rep: Dihydrolipoyl dehydrogenase - Moorella
thermoacetica (strain ATCC 39073)
Length = 459
Score = 369 bits (908), Expect = e-101
Identities = 197/457 (43%), Positives = 285/457 (62%), Gaps = 9/457 (1%)
Query: 34 LVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAKH 93
+ +IG GPGGYVAAI+AAQLG KVV +E+D LGGTCLN GCIP+KALL + + K
Sbjct: 5 IAIIGGGPGGYVAAIRAAQLGAKVVVIEQD-ALGGTCLNRGCIPTKALLAGAAMVRGIK- 62
Query: 94 DFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVEV 153
GI+ + D+ ++ K VK LTGGIA LF+KNKV+L+KG G + P ++EV
Sbjct: 63 GAAAFGIDVEDYRVDYARLAARKDAVVKQLTGGIAYLFKKNKVDLIKGRGFLKGPGQIEV 122
Query: 154 HGEKG-VETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVI 212
G +E + +NI++A+GSE + ++ + ++TST AL+ VP ++L+IG GVI
Sbjct: 123 ATADGTIENLQAENIILATGSEPALIKALGYNGRTVVTSTEALAWTEVPAELLIIGGGVI 182
Query: 213 GLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKE 272
G E +++ LG+ VT +E + +I + ID E+++ +L K G++ K ++ VK+
Sbjct: 183 GCEFATLFATLGSKVTIVEMMPAILPM-IDSEISRRFSMLLKKTGVEIKTKAQITEVKEA 241
Query: 273 GSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQT 332
G +V A G + ++ D VLISIGR+ T+GLGL+ GI L +G I V+ +T
Sbjct: 242 GG--RVQATLADG---QTINADKVLISIGRQFNTRGLGLEDAGITLGPKGEIVVDEYLRT 296
Query: 333 TVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGKT 392
+VPGIYAIGDV + LAH A +G+ V I G P NYDA+PS IYT PE+ VG T
Sbjct: 297 SVPGIYAIGDVTNKIQLAHVASAQGLAAVTTIMGRPTKVNYDAVPSCIYTLPEIAGVGLT 356
Query: 393 EEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELIN 452
+E + G +VGKFPF A+ +A +GET+G VK++++ +D ++G I+GP ELI
Sbjct: 357 KEAAEGRGMKVRVGKFPFQASGKALCSGETDGMVKIIAEAESDRVVGVFIMGPHATELIA 416
Query: 453 EAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAY 489
E LA G A ++A HAHPT +EA+ EA A +
Sbjct: 417 EGALAVNKGITAGELAATIHAHPTLSEAVMEAAEAVH 453
>UniRef50_A7HBV5 Cluster: Dihydrolipoamide dehydrogenase; n=2;
Anaeromyxobacter|Rep: Dihydrolipoamide dehydrogenase -
Anaeromyxobacter sp. Fw109-5
Length = 481
Score = 368 bits (905), Expect = e-100
Identities = 199/467 (42%), Positives = 283/467 (60%), Gaps = 7/467 (1%)
Query: 29 THDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLY 88
T D VVIG+G GGY AAI+ AQLG KV VEK+ TLGG CLN GCIPSKAL+ ++L
Sbjct: 3 TKTFDAVVIGAGVGGYPAAIRLAQLGKKVALVEKE-TLGGVCLNWGCIPSKALIAAANLV 61
Query: 89 HMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAP 148
K +RGI +GE D K+ E+K VK LT G+ +L + N V +VKG T V+
Sbjct: 62 DEIK-GAAERGIVSGEPKVDVAKLREFKNGVVKKLTSGVGLLEKGNGVEVVKGTATFVSA 120
Query: 149 NKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
++V + + ++A+G PG FD K + ++ A+ L VPK+++ IG
Sbjct: 121 TAIDVEQNGERTRIEAQAFIVATGGRPVEIPGFAFDGKDVWSAKEAVDLPEVPKRLVCIG 180
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
G+IG+ELG+VY +LGA VT +E L I G+D E + +QK L ++G+ + K G
Sbjct: 181 GGIIGMELGTVYAKLGAQVTFLEALPQIL-TGVDPEAVRFVQKNLRQRGVTVHVNAKAKG 239
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
+K+G + V E G + ++CD +L+++G RP +GLGL+K+G+ + +G I V+
Sbjct: 240 FEKKGGALAVKAEV--DGKETTIECDKILVAVGFRPSPEGLGLEKIGVKIAPKG-IEVDA 296
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGW 388
+++T+VP ++AIGDV GP LAHKA EG + E I GM ++ A+P I+T PE+G
Sbjct: 297 QYRTSVPSVFAIGDVTGGPFLAHKASKEGEIAAEVIAGMKSARDWVAMPGGIFTDPEIGT 356
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VG +EE+ + G GKF F A RA T+GFVKV++D+ + +ILG ++GP
Sbjct: 357 VGLSEEEARALGHDPITGKFAFGALGRAIAIDHTDGFVKVIADRASKLILGVTVVGPEAA 416
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
+LI EA LA E GA EDVA HAHPT EA EA A G+PI+
Sbjct: 417 DLIAEATLALEMGAYLEDVALTIHAHPTLPEAFMEACKVAL-GEPIH 462
>UniRef50_Q892P7 Cluster: Dihydrolipoamide dehydrogenase; n=3;
Clostridia|Rep: Dihydrolipoamide dehydrogenase -
Clostridium tetani
Length = 589
Score = 365 bits (897), Expect = 2e-99
Identities = 194/462 (41%), Positives = 285/462 (61%), Gaps = 9/462 (1%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
+ D+ ++G+GPGGYVAAI+AA+LG KVV VEKD +GGTCLN GCIP+KA + +S +Y
Sbjct: 130 ECDVAILGAGPGGYVAAIQAAKLGAKVVIVEKDK-VGGTCLNRGCIPTKAFVRSSEVYSN 188
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
K+ K GI + D KK++ K N V L GGI L QK+ + L+ G G ++ N
Sbjct: 189 VKNSEKY-GISLENPSIDIKKVVARKDNIVDKLVGGIQYLIQKHNIELISGNGKLIDRNT 247
Query: 151 VEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
+E + KNI+IASGS+ + P + KQ+ITS AL L+ VP+K+ +IG G
Sbjct: 248 IETKDA----LIKAKNIVIASGSKASVLPIKGSNLKQVITSEEALDLKEVPEKIAIIGGG 303
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
VIG+E +Y +G +V+ IE+ +I + +D +V K + I ++G+KF +KV +
Sbjct: 304 VIGMEFAFIYANMGVEVSVIEYFDNILSM-LDEDVIKEITDIGKEKGIKFYTSSKVEEIL 362
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGR-IPVNNK 329
++ + + V+ G ++ + CD VL+S+GR+PY + +G++++GI L+ R I VN K
Sbjct: 363 EDENEGCI-VKFTNKGEEKFIFCDKVLMSVGRQPYMENMGVEELGIELNQNKRGIKVNTK 421
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWV 389
+T+V IYAIGDV + LAH A +GIV V+ I G + +Y A+PSVI+T PE+ V
Sbjct: 422 METSVSNIYAIGDVTNVIQLAHVASHQGIVAVKNIMGKDIQIDYSAVPSVIFTEPEIAVV 481
Query: 390 GKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGE 449
G E+ K+ +VGKFPF AN +A T GE GF+KV+ +K T ++G IIG +
Sbjct: 482 GVCEKIAKENNLDVEVGKFPFSANGKALTLGEDRGFIKVIKEKATGKVVGASIIGAHASD 541
Query: 450 LINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 491
LI E LA + G +E +A HAHPT AE + EA+LA G
Sbjct: 542 LIAELTLAVKNGLTSEQIAETIHAHPTTAEVVHEASLAVEGG 583
Score = 34.7 bits (76), Expect = 5.7
Identities = 25/109 (22%), Positives = 50/109 (45%), Gaps = 8/109 (7%)
Query: 215 ELGSVYQRLGADVTAIEFLTSI----GGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
++G +++ +G + + E L + G + I + + I ++G K+G +L ++
Sbjct: 45 KVGKIHKSIGDGIKSGEVLVEVEGKKGNIPIKAKEEGKIHSIEIEEGTTVKIGDVLLKIE 104
Query: 271 KEGSTIKVDV----EAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVG 315
E T+ V E AK + L+CDV ++ G Y + K+G
Sbjct: 105 IEEVTLDEFVIDKDEFAKKSELKSLECDVAILGAGPGGYVAAIQAAKLG 153
>UniRef50_Q1R3M3 Cluster: Dihydrolipoyl dehydrogenase; n=4;
Escherichia coli|Rep: Dihydrolipoyl dehydrogenase -
Escherichia coli (strain UTI89 / UPEC)
Length = 472
Score = 364 bits (895), Expect = 3e-99
Identities = 193/462 (41%), Positives = 281/462 (60%), Gaps = 10/462 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEK------DPTLGGTCLNVGCIPSKALLHNSH 86
D+ V+G GPGGYVAA++AAQ G+ VV ++ +P+ GGTCLNVGCIPSK+LL +S
Sbjct: 6 DVAVMGGGPGGYVAALRAAQNGLSVVCIDDGVNAQGEPSPGGTCLNVGCIPSKSLLQSSE 65
Query: 87 LYHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIV 146
LY +H+ G+ V+F+ M++ K V LT GI++LF+KNKV + G+ T+
Sbjct: 66 LYAQVQHEASIHGVNVEGVSFNAAAMIQRKDAIVSRLTMGISLLFKKNKVKHLCGLATLE 125
Query: 147 APNKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLV 206
+ ++ +N++IA+GS+ PGVT D +QI+ + GAL+L VP ++ V
Sbjct: 126 RAQDEIWQLRVNDQHIHARNVVIATGSQPRQLPGVTIDNQQILDNRGALALSEVPPRLGV 185
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
IGAGVIGLELGSV+ R+G+DVT +E + ++ ++ ++K + GMK +L ++
Sbjct: 186 IGAGVIGLELGSVWNRVGSDVTLLEMAPTFLPA-LEARLSNEVRKAMIASGMKMQLAVEI 244
Query: 267 LGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPV 326
+++ V V +G +E D ++++IGR P G+ L ++G+ D+RG I V
Sbjct: 245 EAIEQRDDG--VHVRWRQGEKREESRFDKLILAIGRVPRLSGVDLVQLGLEADNRGGIAV 302
Query: 327 NNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH-FNYDAIPSVIYTSPE 385
+N +T G++AIGDV+ GPMLAHKA EG+V + I G+ V N+ IPSVIYT PE
Sbjct: 303 DNLCRTGKAGLWAIGDVVRGPMLAHKAMAEGVVVADQIAGLAVEPINFALIPSVIYTQPE 362
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGP 445
V WVG+ E LK GR + G F N RA G+ G + SDK TD +LG I+GP
Sbjct: 363 VAWVGENEASLKAAGRVFNKGNSLFAGNGRALALGQEGGRCTLYSDKHTDRVLGGAIVGP 422
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 487
ELINE LA + A+ ED+A HAHPT +E + EA +A
Sbjct: 423 QASELINEIALAMTFSASGEDIACAIHAHPTLSEVIHEAAMA 464
>UniRef50_Q3ETT1 Cluster: Dihydrolipoyl dehydrogenase; n=1; Bacillus
thuringiensis serovar israelensis ATCC 35646|Rep:
Dihydrolipoyl dehydrogenase - Bacillus thuringiensis
serovar israelensis ATCC 35646
Length = 463
Score = 363 bits (893), Expect = 6e-99
Identities = 195/454 (42%), Positives = 276/454 (60%), Gaps = 6/454 (1%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
+ + +VIGSGPGGYVAAI+AAQLG +V +E++ LGG C NVGCIPSKAL+ H +
Sbjct: 7 EIETIVIGSGPGGYVAAIRAAQLGQQVAIIERE-NLGGVCANVGCIPSKALISVGHRFEE 65
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
AK+ + GI + V DF K+ E+K VK L G+ L NKV+++KG + N
Sbjct: 66 AKYS-EDMGIFSSVVNVDFAKVQEFKNGVVKKLVDGVEGLLNSNKVDVIKGEAYFIDANT 124
Query: 151 VEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
+ V + V+T KN +IA+GS P F K++I STGAL+L VP K++VIG G
Sbjct: 125 ICVSNKNAVQTYTFKNAIIATGSRPVEIPPFEFT-KRVINSTGALNLAEVPSKLVVIGGG 183
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
IG ELGS Y LG+ VT IE I G D ++ + L++ L +G+K + GV+
Sbjct: 184 YIGTELGSAYASLGSLVTIIEGGKDIL-TGFDKQMTQILKENLINKGVKIVVDASAKGVE 242
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
+ + + V E GG ++ +D D VLI++GRRP T+ +G +K+GI +RG + ++ +
Sbjct: 243 EVENGVIVTYEI--GGEEKKVDADYVLITVGRRPNTENMGFEKIGIEFSNRGLLKIDQQC 300
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVG 390
+T +P I+AIGD++ GP LAHKA EG V E I G +Y AIP+V +T+PE+ VG
Sbjct: 301 RTNLPNIFAIGDIVAGPQLAHKAFYEGKVAAEAIAGEFSFVDYLAIPAVCFTTPELATVG 360
Query: 391 KTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGEL 450
TEE K E KV KFPF AN A + E +GF+++L+ K +++G I G G E+
Sbjct: 361 YTEEQAKAEDMEVKVVKFPFSANVHAMVSNEEKGFLRLLARKEDGILVGAQIAGNGASEI 420
Query: 451 INEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
I E LA E G ED+A HAHPT +E+L +A
Sbjct: 421 IAEMGLAIEAGMTVEDIALTPHAHPTLSESLMKA 454
>UniRef50_Q13KM1 Cluster: Putative dihydrolipoamide dehydrogenase;
n=1; Burkholderia xenovorans LB400|Rep: Putative
dihydrolipoamide dehydrogenase - Burkholderia xenovorans
(strain LB400)
Length = 474
Score = 363 bits (893), Expect = 6e-99
Identities = 195/465 (41%), Positives = 282/465 (60%), Gaps = 13/465 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+VVIG G GGY AI+A+QLG+ V VE+ +GGT + GCIPS+ LLH S +Y +A
Sbjct: 5 DVVVIGCGAGGYNTAIRASQLGLSVACVERASNIGGTGMRTGCIPSRLLLHTSEIYDLAN 64
Query: 93 HDFKQRGIETG-EVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
K + G T D +MM YKA+ V+ ++ I L +K V L+ G + A +V
Sbjct: 65 KG-KNAALGIGCAPTLDLTQMMAYKASTVEKMSNSIHKLLRKQGVTLIHGDALLAAAGQV 123
Query: 152 EVHGEKGVE-TVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
V GV+ T++ ++IA+GS P P FD +I+ S ALSL VP+ + +IGAG
Sbjct: 124 IVRKTGGVQQTLSGTALVIATGSVPIPLPFAAFDHMRILDSADALSLGKVPRHLAIIGAG 183
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
+G+ELGS++QRLG+ +T IE I +D +V TL++ L ++G+ ++ + V+G+
Sbjct: 184 AVGVELGSIWQRLGSRITLIERCDRICH-WLDRDVTATLERSLRQRGIDIRVSSDVVGLD 242
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGI------ALDDRG-R 323
K ++ V + AA G +D D VL++IGRRP T G+ L VG+ L +G
Sbjct: 243 KHSDSVSVQLRAAASGKITHIDADRVLVAIGRRPSTAGMNLASVGMQTGYKSTLSQQGPA 302
Query: 324 IPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTS 383
PV + T GI+ IGD GPML KAE+E I C E I G+P +Y +IP V++TS
Sbjct: 303 TPVTS--MTNGSGIWVIGDAGPGPMLMSKAEEEAIACAERIAGLPGFVSYPSIPYVLHTS 360
Query: 384 PEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHII 443
PEV +G+TE++L+ G AY+VG +P AN RA G +EGFVK+L D T++I G H+I
Sbjct: 361 PEVAMIGRTEDELRGTGAAYRVGYYPLAANPRAAICGTSEGFVKLLVDADTNLIAGAHLI 420
Query: 444 GPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAA 488
GPG +LI++ +A E ED AR+CH +P +EALR+A +AA
Sbjct: 421 GPGAADLISQVAIAMEASMICEDFARICHPYPVWSEALRQAAMAA 465
>UniRef50_A2F0F6 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Trichomonas vaginalis G3|Rep: Dihydrolipoyl
dehydrogenase - Trichomonas vaginalis G3
Length = 471
Score = 361 bits (887), Expect = 3e-98
Identities = 200/467 (42%), Positives = 278/467 (59%), Gaps = 11/467 (2%)
Query: 27 ATTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSH 86
A T + DL+VIG GPGGY AAI+AA+LG+K V VEK+ +GGTCL GCIPSK L+ SH
Sbjct: 8 AFTQNPDLLVIGGGPGGYAAAIRAAKLGLKTVCVEKEKLMGGTCLREGCIPSKFFLNMSH 67
Query: 87 LYHMAKHDFKQRGIET-GEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTI 145
+ A H+FK GI+ GE D K + GL+ GI L + LV G TI
Sbjct: 68 KVYEANHEFKNFGIKLPGEAAVDMAIAQRRKNGILAGLSAGIEGLIDRAGGELVHGTATI 127
Query: 146 VAPNKVEVHGEKGVETV-NTKNILIASGSEVTPFPGV-TFDEKQIITSTGALSLESVPKK 203
+ N V V E G + N KN+L+A+G++ FP DE+ I TS G L+ + +PK
Sbjct: 128 NSKNDVSVKLEDGKTVIFNPKNLLLATGTDKW-FPKTFPVDEQIIATSQGVLNWKEIPKT 186
Query: 204 MLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLG 263
+ V+G G+IGLELGSV+ LG+ VT ++ +IGG +D + + +Q IL ++GM F LG
Sbjct: 187 LTVVGGGIIGLELGSVFHSLGSKVTIVDMAPTIGGPSVDPMIGRYVQNILKRRGMDFILG 246
Query: 264 TKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGR 323
V K + ++V V G+K+ L + LI+IGRR + G GL+++ + G
Sbjct: 247 KGVDSCTKTENGVEVVV-----GDKK-LQSERALIAIGRRLHLDGFGLERLNLKRQKNGL 300
Query: 324 IPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTS 383
I VNN+ +T+ +YAIGD++ GP LAHKAE+EGI CVE + G ++ + IP+VIYTS
Sbjct: 301 IEVNNRLETSEKNVYAIGDIVPGPQLAHKAEEEGIACVEMLAGHESSYDPNVIPAVIYTS 360
Query: 384 PEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHII 443
PE+ VG T+ K+G KVG FP+ ANSRA+ + GFVK + + V LG I+
Sbjct: 361 PEIATVGLTQNKAAKQGIKTKVGMFPYSANSRARAILDPTGFVKFVCGEDGRV-LGMQIV 419
Query: 444 GPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYS 490
GP GE I E +A + + +A CH HPT +EA+ EA A S
Sbjct: 420 GPNAGEAIMEGAIAIKNKLKIDAIAETCHPHPTLSEAVMEAAKAVLS 466
>UniRef50_A6C4P3 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Dihydrolipoyl
dehydrogenase - Planctomyces maris DSM 8797
Length = 475
Score = 358 bits (880), Expect = 2e-97
Identities = 200/469 (42%), Positives = 275/469 (58%), Gaps = 10/469 (2%)
Query: 27 ATTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSH 86
+ T + D+VVIG GPGGY AA +AA G KV+ V D GG CLN GCIPSKALLH +
Sbjct: 4 SATRETDIVVIGGGPGGYPAAFEAADKGYKVIMVNDDVAPGGVCLNRGCIPSKALLHVAK 63
Query: 87 LYHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIV 146
L + + + GI + + ++ ++K V LTGGI L V ++KG G
Sbjct: 64 LINETRES-AEWGITFQKPEINLDQLRDFKNKVVTQLTGGIGQLAGARNVEILKGFGRFK 122
Query: 147 APNKVEVHGEKGV-ETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKML 205
N VEV + G ET+ K ++A+GS P D+ +I+ STGAL L +P K+L
Sbjct: 123 DANSVEVTKQDGTTETIQFKYAIVATGSSPAVPPVFDLDDDRIMDSTGALELADIPTKLL 182
Query: 206 VIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGV--GIDGEVAKTLQKILSKQGMKFKLG 263
V+G G IGLE+GSVY LG++VT +E GG+ G D ++ + LQK L++ L
Sbjct: 183 VVGGGYIGLEMGSVYAALGSEVTVVEMT---GGLLPGADRDLVRPLQKRLTESFAAIHLN 239
Query: 264 TKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGR 323
TKV + + I D+ ++V D VLISIGRRP KG+G + + LD+RG
Sbjct: 240 TKVEKLTPGDNGITADLSGEGVEPQQVFDR--VLISIGRRPNKKGIGFENTKLELDERGF 297
Query: 324 IPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTS 383
I + + +T P IYAIGD+ PMLAHKA E V +E I G F+ AIP+V++T
Sbjct: 298 IKHDAQQRTAEPHIYAIGDIAGEPMLAHKATREAKVAIESIAGEFGEFDNIAIPAVVFTD 357
Query: 384 PEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHII 443
PE+ W G TE++ K +G ++ +FP+ A+ RA+T G TEG K++ DK T +LG I+
Sbjct: 358 PELAWCGVTEQEAKDQGLDVEITRFPWAASGRAQTLGRTEGLTKMIFDKKTGRVLGVGIV 417
Query: 444 GPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGK 492
GPG GELI E V+A E A AEDVA HAHPT +E L E A++G+
Sbjct: 418 GPGAGELIAEGVMAVEMAAVAEDVAESIHAHPTLSETLME-GAEAFTGQ 465
>UniRef50_P0A9P3 Cluster: Dihydrolipoyl dehydrogenase; n=182;
Bacteria|Rep: Dihydrolipoyl dehydrogenase - Shigella
flexneri
Length = 474
Score = 353 bits (869), Expect = 5e-96
Identities = 188/455 (41%), Positives = 267/455 (58%), Gaps = 4/455 (0%)
Query: 27 ATTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSH 86
+T +VV+G+GP GY AA + A LG++ V VE+ TLGG CLNVGCIPSKALLH +
Sbjct: 2 STEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGVCLNVGCIPSKALLHVAK 61
Query: 87 LYHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIV 146
+ AK + GI GE D K+ +K + LTGG+A + + KV +V G+G
Sbjct: 62 VIEEAKA-LAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLAGMAKGRKVKVVNGLGKFT 120
Query: 147 APNKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLV 206
N +EV GE G +N N +IA+GS P + ++ +I ST AL L+ VP+++LV
Sbjct: 121 GANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDPRIWDSTDALELKEVPERLLV 180
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
+G G+IGLE+G+VY LG+ + +E + D ++ K K +SK+ L TKV
Sbjct: 181 MGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAA-DKDIVKVFTKRISKK-FNLMLETKV 238
Query: 267 LGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPV 326
V+ + I V +E K E D VL++IGR P K L K G+ +DDRG I V
Sbjct: 239 TAVEAKEDGIYVTMEGKKAP-AEPQRYDAVLVAIGRVPNGKNLDAGKAGVEVDDRGFIRV 297
Query: 327 NNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEV 386
+ + +T VP I+AIGD++ PMLAHK EG V E I G +F+ IPS+ YT PEV
Sbjct: 298 DKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEVIAGKKHYFDPKVIPSIAYTEPEV 357
Query: 387 GWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPG 446
WVG TE++ K++G +Y+ FP+ A+ RA + +G K++ DK + ++G I+G
Sbjct: 358 AWVGLTEKEAKEKGISYETATFPWAASGRAIASDCADGMTKLIFDKESHRVIGGAIVGTN 417
Query: 447 GGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
GGEL+ E LA E G AED+A HAHPT E++
Sbjct: 418 GGELLGEIGLAIEMGCDAEDIALTIHAHPTLHESV 452
>UniRef50_Q1IIJ6 Cluster: Dihydrolipoyl dehydrogenase; n=4;
Bacteria|Rep: Dihydrolipoyl dehydrogenase -
Acidobacteria bacterium (strain Ellin345)
Length = 471
Score = 353 bits (868), Expect = 6e-96
Identities = 198/471 (42%), Positives = 277/471 (58%), Gaps = 15/471 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+V+IGSGP GY AAI+A Q G+K +EKD LGGTCL+VGCIP+K+LL N+ +Y K
Sbjct: 7 DVVIIGSGPAGYTAAIRAGQFGLKTALIEKDAKLGGTCLHVGCIPTKSLLFNAEIYDHIK 66
Query: 93 HDFKQRGIE-TGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK- 150
+ ++ GIE G ++ K+ E K + G+ L +KNKV ++ G G + P K
Sbjct: 67 -EAEEFGIEGLGTPKLNWSKVQERKQAIIDKHAKGLQFLMKKNKVTVIPGFGRLTGPAKG 125
Query: 151 ----VEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLV 206
VEV + + V KN+L+++GS PG+ D++ I+T+ LSL+ +PK ++V
Sbjct: 126 GIHSVEVEADGKKQNVQAKNVLLSTGSVARMLPGLQADDR-ILTNIEILSLKEIPKSLVV 184
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
IG+G +G+E S+Y+ G D T IE L + V D EV+K L + K+G+ + K
Sbjct: 185 IGSGAVGVEFASIYKSFGTDCTIIEMLPRLVPVE-DEEVSKELLRNYKKRGINCHVNAKT 243
Query: 267 LGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPV 326
+K + +KV G +E ++ + L++IGR P T+G+G++K I L+ RG +PV
Sbjct: 244 DKFEKTKTGVKVTFTV--DGKQESIEAEKCLVAIGRAPRTEGVGIEKTNIKLE-RGFVPV 300
Query: 327 NNKFQTTVPGIYAIGDVIHG-PMLAHKAEDEGIVCVEGIKGMPVH-FNYDAIPSVIYTSP 384
N QTT PG+YAIGD++ G LAH EG+V V I G P D +P Y P
Sbjct: 301 NEWMQTTEPGVYAIGDIVLGLQQLAHAGAMEGMVAVAHIAGKPTKPVRKDRVPGATYCHP 360
Query: 385 EVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 444
E+G VG TE K+ G K+GKFPF ANSRA + EGFVKV++D ILG HIIG
Sbjct: 361 EIGSVGLTEAQAKEAGHEVKIGKFPFTANSRASIVNQHEGFVKVVADAKHGEILGVHIIG 420
Query: 445 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
P EL+ EAV E A A+ + V HAHPT AEA+ +A A Y G IN
Sbjct: 421 PQATELVAEAVAMLELEATADFMMTVIHAHPTLAEAMLDAVSAVY-GMAIN 470
>UniRef50_A5UXL4 Cluster: Dihydrolipoamide dehydrogenase; n=3;
Chloroflexi (class)|Rep: Dihydrolipoamide dehydrogenase
- Roseiflexus sp. RS-1
Length = 471
Score = 353 bits (868), Expect = 6e-96
Identities = 194/468 (41%), Positives = 281/468 (60%), Gaps = 9/468 (1%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D++VIG GPGGYVAAI+AAQLG+K VE+ +GG CLNVGCIP+KALLH + L +
Sbjct: 7 DVIVIGGGPGGYVAAIRAAQLGLKTAVVERQ-AMGGVCLNVGCIPTKALLHTADLLDELR 65
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ K+ G+ V+ D++ + K VK +T G++ L +KNK+++V G + +V
Sbjct: 66 -EAKRFGVIVEGVSLDWEATLRQKDTVVKTMTSGVSFLMKKNKIDVVNGSARLAGRGQVA 124
Query: 153 VHGEKGVE-TVNTKNILIASGSEVTPFP--GVTFDEKQIITSTGALSLESVPKKMLVIGA 209
V +G T+ K+I+IA G+ P G FD +I++STG L++ +VPK +LV+GA
Sbjct: 125 VSSPEGQHRTLTAKHIIIAVGARPREIPAIGAVFDNDRILSSTGGLNIPTVPKSLLVVGA 184
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
G IG+E S+Y+ GA+VT +E L + + D EV+ L + L+++G+K G K+ +
Sbjct: 185 GAIGVEFASMYRAFGAEVTLVEMLPRVVPLE-DEEVSAELARALNRRGIKIFAGAKLNNL 243
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
+K + + +G + L + L+ +G P T +GL++VG+ALD RG I V++
Sbjct: 244 EKVDGGVMARLVDVQGA-EHALTFERALVGVGIVPNTSDIGLEEVGVALDPRGFIKVDDH 302
Query: 330 FQTTVPGIYAIGD-VIHGPMLAHKAEDEGIVCVEGIKGMPVH-FNYDAIPSVIYTSPEVG 387
+T V GIYAIGD P LAHKA EGIV E I G +Y IP+ Y +PE+
Sbjct: 303 MRTNVEGIYAIGDCATTTPWLAHKASAEGIVAAETIAGHHTQPLDYGKIPACTYCNPEIA 362
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG TE +++G KVGKF F N +A G+ +GFVK+++DK D +LG H+IGP
Sbjct: 363 SVGLTEAKAREQGYDVKVGKFAFTGNGKATILGQRQGFVKIVADKQYDEVLGIHMIGPRV 422
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
ELI E LA + A AE + R HAHPT EA+ EA AA G I+
Sbjct: 423 TELIAEGGLALSHEATAESIMRTVHAHPTLYEAIVEAAHAAAEGAAIH 470
>UniRef50_Q1IMV9 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Bacteria|Rep: Dihydrolipoyl dehydrogenase -
Acidobacteria bacterium (strain Ellin345)
Length = 474
Score = 351 bits (864), Expect = 2e-95
Identities = 188/453 (41%), Positives = 262/453 (57%), Gaps = 4/453 (0%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
++ VIG GPGGY AA AA LGM V ++ + GG CL GCIPSKALLH + L AK
Sbjct: 8 NIAVIGGGPGGYAAAFLAADLGMTVTLIDMELNPGGVCLYRGCIPSKALLHVAKLIEEAK 67
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
H G+ D +++ +K VK LTGG+ L ++ KV ++G T+V V+
Sbjct: 68 HSTNW-GVTYDAPKIDLERLRTFKEGVVKKLTGGLGQLSKQRKVTYIQGKATLVDSCTVK 126
Query: 153 VHGEKG-VETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGV 211
V G ET++ +++A+GS P +++ STGAL+LE +PK++LV+G G
Sbjct: 127 VEKTAGGEETLHFDKLILATGSRPAVIPAFNIGSPRVMDSTGALNLEDIPKRLLVVGGGY 186
Query: 212 IGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKK 271
IGLELGSVY +G+ V+ +E + G D ++ L K L+ L T V+ +
Sbjct: 187 IGLELGSVYAAIGSKVSVVEMTAGLLP-GADRDLVAPLHKRLTGIFEAIMLNTTVISIAD 245
Query: 272 EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQ 331
GS +KV + + G +E D VL+S+GR+P ++ GLDK + ++ +G + VN
Sbjct: 246 TGSAVKVKFKT-QDGKEEEQTYDRVLVSVGRKPNSQIPGLDKTRVKVNQKGFLQVNPSLM 304
Query: 332 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGK 391
T P IYAIGDV+ PMLAHKA EG+V VE I G V F AIP+V++T PE+ W G
Sbjct: 305 TDDPFIYAIGDVVGEPMLAHKASHEGLVAVESIAGHKVAFEPQAIPAVVFTDPEIAWAGL 364
Query: 392 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 451
TE + EGR V KFP+ A+ RA T TEG K++ D T+ +LG I GPG GE+I
Sbjct: 365 TETQAQNEGREVTVTKFPWAASGRAVTIDRTEGLTKLIIDPQTERVLGVGICGPGAGEMI 424
Query: 452 NEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
E V+A E GA A D+ H HPT +E + EA
Sbjct: 425 AEGVVAIEMGALAGDIKLSIHPHPTLSETIMEA 457
>UniRef50_Q1EVV0 Cluster: Dihydrolipoyl dehydrogenase; n=6;
Clostridium|Rep: Dihydrolipoyl dehydrogenase -
Clostridium oremlandii OhILAs
Length = 467
Score = 351 bits (864), Expect = 2e-95
Identities = 198/459 (43%), Positives = 281/459 (61%), Gaps = 14/459 (3%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
+ D+V+IG GPGGYVAAI+ AQLG KV +E++ LGGTCLNVGCIP+KAL N+ +
Sbjct: 2 EKDIVIIGGGPGGYVAAIRGAQLGGKVTLIEEN-ALGGTCLNVGCIPTKALCKNAEVIST 60
Query: 91 AKH--DFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAP 148
K+ +F +GIE + D +K+ E K N + L GGI + V +++G GTI+
Sbjct: 61 LKNIEEFGIKGIENYSI--DVEKIQERKQNVIDQLVGGIHTVLSAYGVEILRGRGTILNK 118
Query: 149 NKVEVHGEKGVET-VNTKNILIASGSEVT--PFPGVTFDEKQIITSTGALSLESVPKKML 205
N V+ G E + KNI+IA+G++ T P PG+ + ++TS LS + +PK++
Sbjct: 119 NLVKATLVTGEEREIPAKNIIIATGAKPTLPPIPGIHLNG--VMTSNELLSFKEIPKRLA 176
Query: 206 VIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTK 265
+IG GVIG+E ++ LG++VT EF SI + +D +++K L L K G+K T
Sbjct: 177 IIGGGVIGIEFAGIFNALGSEVTVFEFAPSIL-IKLDKDISKRLTTSLKKDGIKINTSTG 235
Query: 266 VLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIP 325
V +K+ ++ + V K G+ EV + D VL+S+GR P +GL L+ +GI LD R RI
Sbjct: 236 VEEIKESNGSLVI-VAKDKKGSIEV-EVDQVLVSVGRTPVIEGLNLEGIGIELD-RKRIQ 292
Query: 326 VNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPE 385
VN++F+T V G+YAIGDV G MLAH+A EG E I PV + +PS I+ SPE
Sbjct: 293 VNDRFETNVKGVYAIGDVNGGMMLAHEASHEGKSVAEIIMDAPVSEDRGVVPSCIFISPE 352
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGP 445
+ VG TEE+ K++G YK KF F AN +A + GE +GFVKV+S + I+G HI+GP
Sbjct: 353 ISTVGITEEEAKEQGIDYKTSKFMFGANGKALSMGEPQGFVKVISTGENNRIIGVHIMGP 412
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
+LI+E LA A+D+A HAHPT EA EA
Sbjct: 413 HAADLIHEGALAIRNQLTADDIASTIHAHPTLGEAFVEA 451
>UniRef50_A1HU83 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Dihydrolipoyl
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 466
Score = 350 bits (861), Expect = 4e-95
Identities = 205/465 (44%), Positives = 274/465 (58%), Gaps = 12/465 (2%)
Query: 34 LVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAKH 93
+V+IG GPGGYVAAI+AAQLG +V VE D LGGTCLNVGCIP+K+LLH + LY +
Sbjct: 5 IVIIGGGPGGYVAAIRAAQLGAEVHLVEAD-RLGGTCLNVGCIPTKSLLHTAQLYREVQK 63
Query: 94 DFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVEV 153
G++ V D+ + K V L G+ L + NKV + KG + V V
Sbjct: 64 G-GLIGLKADNVRVDWPVLQSRKQATVTRLVKGVESLLKANKVTVHKGQAALKDARTVIV 122
Query: 154 HGEKGVETVNTKNILIASGSEVTP--FPGVTFDEKQIITSTGALSLESVPKKMLVIGAGV 211
GE E V I++A+GSE FPG +I ST ALSL SVP ++++G GV
Sbjct: 123 SGETEKE-VAADIIVLATGSEPVKLNFPGAELPG--VIDSTAALSLPSVPTSLVIVGGGV 179
Query: 212 IGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKK 271
+G+E ++Y LGA VT +E L I +DGE+A +++ L++QG+ F G ++ V++
Sbjct: 180 VGIEFAALYSALGARVTVVELLPEILPP-VDGEIAVKVRQELTRQGVTFLTGARLTEVRQ 238
Query: 272 EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQ 331
+ VEA GG E + + VL+++GRRP T+GLGL+ VG+ALD RGRI V+ F
Sbjct: 239 GDGALTALVEA--GGKVEEVTGEYVLVAVGRRPRTQGLGLEAVGVALD-RGRITVDEHFV 295
Query: 332 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGK 391
TTVPGIYA+GD MLAH A +GI VE G + IPS IY PEV VG
Sbjct: 296 TTVPGIYAVGDCNGQIMLAHAASAQGIAAVEHALGHQAAYYPQTIPSCIYIQPEVAGVGL 355
Query: 392 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 451
TEE+ KK+G AYK G FP A+ +A +G G VKV++ + ILG HI GP +LI
Sbjct: 356 TEEEAKKQGIAYKTGLFPLSASGKAVIDGGMSGLVKVIAGEKYGEILGVHIFGPRATDLI 415
Query: 452 NEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 496
EA LA A +++ H HPT +EAL EA LA GK I++
Sbjct: 416 GEAALAIRLEATVDELVTTIHGHPTISEALAEAALAV-DGKAIHW 459
>UniRef50_P54533 Cluster: Dihydrolipoyl dehydrogenase; n=41;
Firmicutes|Rep: Dihydrolipoyl dehydrogenase - Bacillus
subtilis
Length = 474
Score = 349 bits (858), Expect = 1e-94
Identities = 193/474 (40%), Positives = 284/474 (59%), Gaps = 15/474 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+V++G G GGYVAAI+AAQLG+K VEK+ LGGTCL+ GCIPSKALL ++ +Y A+
Sbjct: 6 DVVILGGGTGGYVAAIRAAQLGLKTAVVEKEK-LGGTCLHKGCIPSKALLRSAEVYRTAR 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPN--- 149
+ Q G+ET V+ +F+K+ + K V L G+ L +K K+++ G G I+ P+
Sbjct: 65 -EADQFGVETAGVSLNFEKVQQRKQAVVDKLAAGVNHLMKKGKIDVYTGYGRILGPSIFS 123
Query: 150 ----KVEVHGEKGVET--VNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKK 203
+ V G E + K ++IA+GS PG+ D K ++TS AL +E +P+
Sbjct: 124 PLPGTISVERGNGEENDMLIPKQVIIATGSRPRMLPGLEVDGKSVLTSDEALQMEELPQS 183
Query: 204 MLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLG 263
++++G GVIG+E S+ G VT IE+ I D E++K ++ +L K+G++F G
Sbjct: 184 IIIVGGGVIGIEWASMLHDFGVKVTVIEYADRILPTE-DLEISKEMESLLKKKGIQFITG 242
Query: 264 TKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGR 323
KVL ++ + ++A K G + +L+SIGR+ +G+GL+ I ++ G
Sbjct: 243 AKVLPDTMTKTSDDISIQAEKDGETVTYSAEKMLVSIGRQANIEGIGLENTDIVTEN-GM 301
Query: 324 IPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH-FNYDAIPSVIYT 382
I VN QT IYAIGDVI G LAH A EGI+ VE G+ H + +P IY+
Sbjct: 302 ISVNESCQTKESHIYAIGDVIGGLQLAHVASHEGIIAVEHFAGLNPHPLDPTLVPKCIYS 361
Query: 383 SPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHI 442
SPE VG TE++ K G K+GKFPF+A +A GE++GFVK+++D+ TD ILG H+
Sbjct: 362 SPEAASVGLTEDEAKANGHNVKIGKFPFMAIGKALVYGESDGFVKIVADRDTDDILGVHM 421
Query: 443 IGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 496
IGP ++I+EA LA+ A +V + H HPT +EA+ EA LAA GK I+F
Sbjct: 422 IGPHVTDMISEAGLAKVLDATPWEVGQTIHPHPTLSEAIGEAALAA-DGKAIHF 474
>UniRef50_Q59299 Cluster: Dihydrolipoyl dehydrogenase; n=6;
Clostridium|Rep: Dihydrolipoyl dehydrogenase -
Clostridium magnum
Length = 578
Score = 347 bits (852), Expect = 5e-94
Identities = 198/459 (43%), Positives = 278/459 (60%), Gaps = 12/459 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
+LVVIG GPGGYVAAI+AAQLG KV +EK+ +LGGTCLNVGCIP+K LLH+S L K
Sbjct: 117 NLVVIGGGPGGYVAAIRAAQLGAKVTLIEKE-SLGGTCLNVGCIPTKVLLHSSQLLTEMK 175
Query: 93 HDFKQRGIET-GEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
K GI+ G + ++K + + K +K L G++ L NKV ++KG + + +
Sbjct: 176 EGDKL-GIDIEGSIVVNWKHIQKRKKIVIKKLVSGVSGLLTCNKVKVIKGTAKFESKDTI 234
Query: 152 EVHGEKGV-ETVNTKNILIASGSEVTPF-PGVTFDEKQ-IITSTGALSLESVPKKMLVIG 208
V E GV E VN N +IA+GS PF P + ++ +I STGALSLES P+ + +IG
Sbjct: 235 LVTKEDGVAEKVNFDNAIIATGS--MPFIPEIEGNKLSGVIDSTGALSLESNPESIAIIG 292
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
GVIG+E S++ LG V+ IE L I +D E+++ + L + G+ KV
Sbjct: 293 GGVIGVEFASIFNSLGCKVSIIEMLPHILPP-MDREISEIAKAKLIRDGININNNCKVTR 351
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
+++ +KV KG +E +D + VLI++GRR +GL ++K+G+ + G I VN+
Sbjct: 352 IEQGEDGLKVSFIGDKG--EESIDVEKVLIAVGRRSNIEGLDVEKIGVKTEG-GSIIVND 408
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGW 388
K +T V GIYAIGD MLAH A D+G+V E I G +Y +P+ +YT PE+
Sbjct: 409 KMETNVEGIYAIGDCTGKIMLAHVASDQGVVAAENIMGQNKKMDYKTVPACVYTKPELAS 468
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VG TEE K++G YKVGKF AN ++ ET G +K+++DK + ILG HI+GP
Sbjct: 469 VGLTEEQAKEKGIDYKVGKFQLAANGKSLIMNETGGVIKIITDKKYEEILGVHILGPRAT 528
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 487
+LI EA LA A E++ HAHPT EA++EA LA
Sbjct: 529 DLITEAALALRLEATLEEIITTVHAHPTVGEAMKEAALA 567
>UniRef50_Q18ZH8 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Desulfitobacterium hafniense|Rep: Dihydrolipoyl
dehydrogenase - Desulfitobacterium hafniense (strain
DCB-2)
Length = 461
Score = 347 bits (852), Expect = 5e-94
Identities = 193/460 (41%), Positives = 274/460 (59%), Gaps = 8/460 (1%)
Query: 36 VIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAKHDF 95
++G GPGGYV A++AAQLG+ VV VEK+ LGGTCLN GCIP+K L+ ++ L+ KH
Sbjct: 8 ILGGGPGGYVCALRAAQLGLSVVLVEKE-RLGGTCLNKGCIPTKTLVKSAELWREIKHA- 65
Query: 96 KQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVEVHG 155
++ GI+ G + ++ K V L GI L + K+ ++KG G + N++EV
Sbjct: 66 EEFGIQLGGALLHYPQIAARKKEVVNTLVSGIEQLMKAKKITVLKGWGEVKEANRIEVTT 125
Query: 156 EKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVIGLE 215
E G ++ +N+++A+GS T P D ++TS L E++P ++VIG GVIGLE
Sbjct: 126 ETGKVELHVENLVLATGSIPTKIPVPGVDLPGVVTSEELLEQETLPDSLVVIGGGVIGLE 185
Query: 216 LGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKEGST 275
S+Y G V+ +E L S+ ID E+ K L +L + G++ V +K +
Sbjct: 186 FASIYHEFGVKVSVVEMLPSLLP-NIDEEIPKRLAPLLKRSGLEILTKAFVREIKPKEEG 244
Query: 276 IKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQTTVP 335
+ V VE KG KE L VL++ GRRP G+ D +G+ LD RG I VN++ QT+VP
Sbjct: 245 LVVIVEDGKG-LKE-LPAQQVLLATGRRPSLSGIHGDALGLELD-RGAIKVNSQMQTSVP 301
Query: 336 GIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGKTEED 395
+YA+GDV+ G MLAH A +G+V E + G V AIPS I+T PE+ VG+TE+
Sbjct: 302 KVYALGDVVGGAMLAHVASMQGMVAAEHMAGQQVSMEGRAIPSAIFTYPEIAAVGETEQA 361
Query: 396 LKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELINEAV 455
LK G+ YKV KFPF AN +A GE G VK+L+D+ V++G I+GP LI E V
Sbjct: 362 LKASGQNYKVSKFPFSANGKALALGEIMGLVKLLADE-EGVVIGASIMGPQASSLIQECV 420
Query: 456 LAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
LA E AED+A++ HAHPT EA+ EA S KP++
Sbjct: 421 LAVEKKIKAEDLAKIIHAHPTLPEAIMEA-AHGISAKPLH 459
>UniRef50_Q8CU56 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Bacillales|Rep: Dihydrolipoyl dehydrogenase -
Staphylococcus epidermidis (strain ATCC 12228)
Length = 504
Score = 346 bits (850), Expect = 9e-94
Identities = 187/452 (41%), Positives = 271/452 (59%), Gaps = 4/452 (0%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL+VIG+G GGYVAAI+AAQLG KVV V+K LGG CLN GCIPSKAL+ S K
Sbjct: 41 DLLVIGAGSGGYVAAIRAAQLGKKVVLVDK-AELGGVCLNRGCIPSKALISASERVKHIK 99
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
H +GEV D +++++K V LT GI L + N V ++ G + + +
Sbjct: 100 HANTMGLKVSGEVQVDMPEVVKWKDGIVNKLTDGIRTLLKGNGVEVISGEAYLTEAHIAK 159
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVI 212
+ E + + K++++A GS + FD+K+II+ST AL L+ VP ++V+G G I
Sbjct: 160 IKIEDEEQIFSYKDLILAIGSLPVELKSMPFDQKRIISSTEALQLQEVPNHLVVVGGGYI 219
Query: 213 GLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKE 272
GLELG+ Y + GA VT +E +I G D + KT+++ L + G+ V G +
Sbjct: 220 GLELGTAYAKFGAKVTILEGSDTILS-GTDPILTKTVKRHLKEIGITVITDALVQGGENT 278
Query: 273 GSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQT 332
G + V V+ G +E++ CD L+SIGR+P T +GL+ +G+ LDD+G I +NNK QT
Sbjct: 279 GDEVNVHVQV--DGKEEIIQCDYCLVSIGRKPNTGKIGLENIGVVLDDQGFIKINNKCQT 336
Query: 333 TVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGKT 392
+ +YAIGD G +LAHKA E + E I G ++ A+P VI++ PEV + G T
Sbjct: 337 NIEHVYAIGDCAGGDLLAHKASYEAKIAAEVISGQNSVIDFQAMPFVIFSDPEVAYTGLT 396
Query: 393 EEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELIN 452
E++ K++G +FPF AN+RA + + +GFV+V+++K T +LG ++GP LI
Sbjct: 397 EKEAKEKGYETVSSRFPFQANARALSVSDADGFVQVVAEKNTKRVLGVQMVGPEVSSLIA 456
Query: 453 EAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
EAV A E GA AED++ HAHPT E L EA
Sbjct: 457 EAVFAIEAGANAEDLSLTIHAHPTLPEPLMEA 488
>UniRef50_A5EK01 Cluster: Dihydrolipoyl dehydrogenase; n=22;
Bacteria|Rep: Dihydrolipoyl dehydrogenase -
Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Length = 473
Score = 345 bits (848), Expect = 2e-93
Identities = 188/472 (39%), Positives = 279/472 (59%), Gaps = 15/472 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+++IGSGPGGYV AI+AAQLG K +EK LGG CLN GCIP+KALL ++ +YH +
Sbjct: 7 DVIIIGSGPGGYVTAIRAAQLGFKTAIIEKS-YLGGICLNWGCIPTKALLRSAEIYHYMQ 65
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
H K G+ ++++D K ++ K L G+ L +KNKV ++ G I AP K+
Sbjct: 66 HA-KDYGLSAEKISYDPKAVVARSRGVSKRLNDGVGFLMKKNKVQVIWGKAAIDAPGKIT 124
Query: 153 V--------HGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKM 204
V G G T K+I++A+G+ PG+ D+K + T A+ E +PK +
Sbjct: 125 VTKSDVESPKGALGEGTYQAKHIIVATGARPRVLPGLEPDKKLVWTYFEAMVPEKMPKSL 184
Query: 205 LVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGT 264
LV+G+G IG+E S ++ +G++VT +E L I V D E+A +K L KQG+K G
Sbjct: 185 LVVGSGAIGIEFASFFRTMGSEVTVVEVLPQILPVE-DAEIAGIARKQLEKQGLKIMTGA 243
Query: 265 KVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRI 324
KV + K+ ++ ++ KG E ++ + V+ ++G + LGL+K+G+ D RG I
Sbjct: 244 KVTKLDKKTDSVVATIDDGKG-KIEAVEFERVISAVGVVGNIENLGLEKLGVKTD-RGCI 301
Query: 325 PVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH-FNYDAIPSVIYTS 383
++ +T VPGIYAIGDV PMLAHKAE EG+VC+E IKG+ H + + IP Y
Sbjct: 302 VIDGYGKTNVPGIYAIGDVAGPPMLAHKAEHEGVVCIEAIKGLHPHAMDKNLIPGCTYCH 361
Query: 384 PEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHII 443
P++ VG TE K++GR +VG+FPF+ N +A GE +G VKV+ DK T ++G H++
Sbjct: 362 PQIASVGLTEAKAKEQGRDIRVGRFPFVGNGKAIALGEDQGLVKVIFDKKTGQLIGAHMV 421
Query: 444 GPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
G ELI V+A E++ HPT +E ++EA L AY G+ +N
Sbjct: 422 GAEVTELIQGYVVAMNLETTEEELMHTVFPHPTLSEMMKEAVLDAY-GRVLN 472
>UniRef50_Q1AT12 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Bacteria|Rep: Dihydrolipoyl dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 471
Score = 345 bits (847), Expect = 2e-93
Identities = 186/471 (39%), Positives = 287/471 (60%), Gaps = 12/471 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPT--LGGTCLNVGCIPSKALLHNSHLYHM 90
DLV+IG G GY+ AI+A+QLGM V VE+ LGGTCLN+GCIP+KALL + + H
Sbjct: 6 DLVIIGGGNAGYIPAIRASQLGMSVALVERREGGHLGGTCLNLGCIPTKALLQTAAMLHD 65
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
A++ ++ G++ G+V FD+++ + + V L G+A L +KNKV++ G G+ + P +
Sbjct: 66 ARNG-EEFGVKVGDVRFDYRQAAKRRDQVVNQLRRGVAGLMKKNKVSVYNGTGSFIQPRR 124
Query: 151 VEVH-GEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSL-ESVPKKMLVIG 208
++V + G E + +N+LIA+GS V PG+ FD +++I+S ++ + P+ ++++G
Sbjct: 125 IKVELNDGGTEELEAENVLIATGSAVNTLPGLEFDGEKVISSDDVVTENDGYPESVIILG 184
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVL- 267
+G +G+E S+Y G +VT +E L + + D EV+ L+K +G++ GTK
Sbjct: 185 SGAVGVEFASMYNDFGTEVTIVEILDRLVPLE-DPEVSAELEKQFEGRGIRCLTGTKADP 243
Query: 268 -GVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPV 326
+ K G +K+ V A +GG +E L+ + +L+++GR+ T+ L L+ + DDRG I V
Sbjct: 244 GSLDKSGDGVKIKV-AGEGG-EETLEAEKLLVAVGRKTVTEELNLEATSVKTDDRGIIQV 301
Query: 327 NNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGM-PVHFNYDAIPSVIYTSPE 385
+ ++T PG+YA GDVI G LAH A EGIV VE + G P+ + + IP V + PE
Sbjct: 302 DEFYRTDEPGVYAAGDVIGGYWLAHAAGHEGIVAVEHMAGKDPMPLDQNLIPRVTFCRPE 361
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGP 445
+ G +EE ++EG KVGKFPF A +A GE GF+KV++D TD+ILG H IGP
Sbjct: 362 IASFGLSEEQAREEGYEIKVGKFPFRAIGKALIEGEPNGFLKVVADAETDLILGMHAIGP 421
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 496
ELI E V A+ E++ HAHP+ AE + EA +A G I+F
Sbjct: 422 HVTELIAEGVFAKLVEGTPEEIGMAVHAHPSLAEIVGEAAMAV-DGHAIHF 471
>UniRef50_A4J8D3 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Desulfotomaculum reducens MI-1|Rep: Dihydrolipoyl
dehydrogenase - Desulfotomaculum reducens MI-1
Length = 463
Score = 341 bits (837), Expect = 4e-92
Identities = 185/457 (40%), Positives = 262/457 (57%), Gaps = 6/457 (1%)
Query: 28 TTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHL 87
T D+VVIG GPGGY AA +AA LG +V VEK+ LGGTCLN GCIP+K LL ++ +
Sbjct: 2 TNETFDVVVIGGGPGGYTAAARAAALGGRVALVEKE-ALGGTCLNQGCIPTKTLLKSTEV 60
Query: 88 YHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVA 147
K K G+E G +K++ K +K L G+ L + K+++ +G G I
Sbjct: 61 LETVKKA-KDFGVEVGVPEVALEKLINRKQAVIKRLNTGVEFLMKSGKISVFQGEGKITG 119
Query: 148 PNKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVI 207
N++ V + T+ I+IA+GS PG+ D ++II S AL L VP +L+I
Sbjct: 120 ANEITVSNPSKQVILRTQKIIIATGSRPAVIPGLETDGEKIINSNHALMLSDVPGSLLII 179
Query: 208 GAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVL 267
G G IG+E S+Y +LGA VT +E + I D EV+ L+++++++ + KV
Sbjct: 180 GGGAIGVEFASIYHKLGAKVTLVEAMDRILPFA-DEEVSNGLKQLMTREKISILTSAKVS 238
Query: 268 GVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVN 327
GV + V+V+ KG + D VL+++GRRP + LGL+++GI ++ RGRI VN
Sbjct: 239 GVNNSEEGLLVNVDTPKGIQE--FRVDKVLVAVGRRPNVENLGLEEIGIQIE-RGRIVVN 295
Query: 328 NKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVG 387
+T VP IYA+GD G +LAH A EGIV G +Y +PS IYTSPE+
Sbjct: 296 TYMETNVPNIYAVGDATGGILLAHVASTEGIVAAANAMGGHKEMDYAVVPSCIYTSPELA 355
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG TE K++G VGK F + +A GE +G VK+++D ILG HI+GP
Sbjct: 356 SVGITEAQAKEQGIQVVVGKSQFTGSGKALAMGENKGLVKIIADVENGKILGVHILGPQA 415
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
LI+EA LA + GA AED+A HAHP+ E + EA
Sbjct: 416 TSLISEATLAIKLGATAEDMAETIHAHPSLPETVMEA 452
>UniRef50_Q67SE4 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Lactobacillales|Rep: Dihydrolipoyl dehydrogenase -
Symbiobacterium thermophilum
Length = 470
Score = 339 bits (833), Expect = 1e-91
Identities = 183/457 (40%), Positives = 270/457 (59%), Gaps = 8/457 (1%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+VVIG+GPGGYVAA +A+QLG+ V +E++ LGGTCLN GCIPSKAL+ L +
Sbjct: 9 DVVVIGAGPGGYVAAQRASQLGLDVTLIEREE-LGGTCLNHGCIPSKALISVGDLLYKVN 67
Query: 93 HDFKQRGIETGEVTFDFKKMMEYK-ANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
+ ++ + G V DF K E+K +K LT G+A L + +V +VKG P+ +
Sbjct: 68 NAAERGLVVKGSVEVDFAKTQEWKETKVIKRLTSGVASLMKAGQVEVVKGTARFTDPHSL 127
Query: 152 EVH-GEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
EV + G K+ +IA+GS D + ++ + GAL+ +P + +V+G G
Sbjct: 128 EVELNDGGTAAYTFKHAIIATGSTAVNPSFFPLDGENVVDARGALAFREIPPRFVVVGGG 187
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
IG+ELG Y +LG+ VT +E + G D ++ L + L + G+ L + G
Sbjct: 188 YIGVELGIAYAKLGSKVTIVEATGQLLP-GTDPDLVNVLMRRLRRLGVTVMLNARASGGL 246
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
+ G KV V+ +G E+ + D VL+S+GR PYT+GL LDK G+ +D++G IPV+ +
Sbjct: 247 QNG---KVKVQDGEGKVHEI-EADKVLVSVGRVPYTEGLHLDKAGVRVDEKGFIPVDEQM 302
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVG 390
+T VP IYAIGDV MLAHKA +G V E I G P ++ +P+VI+T PE+ +VG
Sbjct: 303 RTNVPHIYAIGDVCSPVMLAHKASAQGRVAAEAIAGRPSAADWQTVPAVIFTDPEIAYVG 362
Query: 391 KTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGEL 450
TE +++G V ++ F A RA T GE++G VK++ D+ + ++LG ++GP EL
Sbjct: 363 LTEAQAREKGYDPVVSRYNFAAVGRALTMGESDGMVKLVGDRQSGLLLGAQMVGPEVSEL 422
Query: 451 INEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 487
I E LA E GA EDVA H HPT +E + EA L+
Sbjct: 423 IGEIALAIEMGAQMEDVALTPHYHPTLSEGILEAALS 459
>UniRef50_Q189R5 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Clostridiaceae|Rep: Dihydrolipoyl dehydrogenase -
Clostridium difficile (strain 630)
Length = 461
Score = 339 bits (833), Expect = 1e-91
Identities = 199/457 (43%), Positives = 270/457 (59%), Gaps = 19/457 (4%)
Query: 34 LVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAKH 93
+VV+G GPGGYVAAIKA+ LG V VEK +GGTCLN GCIP+KALL +S + + K
Sbjct: 3 IVVVGGGPGGYVAAIKASMLGADVTVVEKR-RVGGTCLNAGCIPTKALLASSGVLNTVK- 60
Query: 94 DFKQRGIET-GEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ K GIE G V +F +ME K V L GI LF+K VNLV G G ++ N +E
Sbjct: 61 EAKDFGIEIDGTVKPNFTAIMERKNKVVNQLISGIEFLFEKRGVNLVNGFGKLIDKNTIE 120
Query: 153 VHGEKG-VETVNTKNILIASGS-EVTP--FPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
V + G VET+ I++A+GS V P FP +D K +ITS L LE +P+ ML++G
Sbjct: 121 VTKDDGTVETIKADKIILANGSVPVVPRMFP---YDGKVVITSDEVLGLEEIPESMLIVG 177
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
GVIG E+G ++ LG +VT +E + I + D +VAK L + K +K G +G
Sbjct: 178 GGVIGCEIGQFFRALGTEVTIVEMVDQIL-LNEDKDVAKQLLRQFKKDKIKVITG---IG 233
Query: 269 VKKEGSTIKVDVEA-AKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVN 327
V+ + VD +A A N +V++ L+ +GRRP G++ +GI ++ RG++ VN
Sbjct: 234 VQ---TCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVEDIGIEME-RGKVVVN 289
Query: 328 NKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVG 387
+T V GIYAIGD+I P LAH A EGIV VE G +Y AIP +YT PEV
Sbjct: 290 EHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVDYRAIPRCVYTEPEVA 349
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VGKTE+ L+ EG Y VG+F F +A+ G +GFVKV++DK TD I+G ++GP
Sbjct: 350 GVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIADKETDKIIGAAVVGPHA 409
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
+L+ E LA G E V H HP+ +E L EA
Sbjct: 410 TDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEA 446
>UniRef50_Q5UWH2 Cluster: Dihydrolipoyl dehydrogenase 3; n=6;
Halobacteriaceae|Rep: Dihydrolipoyl dehydrogenase 3 -
Haloarcula marismortui (Halobacterium marismortui)
Length = 477
Score = 330 bits (812), Expect = 4e-89
Identities = 185/463 (39%), Positives = 267/463 (57%), Gaps = 12/463 (2%)
Query: 29 THDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLY 88
T D++VIG+GPGGYVAAI+AAQL + V VEK GG CLN GCIPSKAL+H S L
Sbjct: 7 TTSTDVLVIGAGPGGYVAAIRAAQLALDVTLVEKGE-YGGACLNRGCIPSKALIHGSKLA 65
Query: 89 HMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAP 148
A ++ GI + T +M+ +K V LT GI L VNL+KG
Sbjct: 66 SEAGQA-EELGIYA-DPTVALDEMINWKDGVVDQLTSGIEQLCTAAGVNLLKGTAEFADE 123
Query: 149 NKVEV--HGE-KGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKML 205
NKV + GE +G E++ +N +IA+GS PG F++++I++S GAL+ ++VP +++
Sbjct: 124 NKVRIIHQGEGQGSESLKFENCIIATGSRPIEIPGFGFEDERIVSSDGALNFDTVPDELV 183
Query: 206 VIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLG-T 264
++GAG IG+EL +VY RLG+DV+ IE L + ++A ++K + G+ F G T
Sbjct: 184 IVGAGYIGMELATVYSRLGSDVSVIEMLEQ-ALPSYEEDIASIVRKRAERLGVDFHFGYT 242
Query: 265 KVLGVKKEGSTIKVDV---EAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDR 321
+G + V EAA + E L D +L+++GRRP T L +D G+ + +
Sbjct: 243 ADSWAASDGKAVLTAVPADEAAHDSDIE-LTADRILVAVGRRPVTDTLSIDDAGVETNAQ 301
Query: 322 GRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIY 381
G IP ++ +T I+A+GDV PMLAHK EG V E I G P +Y A+P+ ++
Sbjct: 302 GFIPTDSTCRTNKEHIFAVGDVAGEPMLAHKGSKEGEVAAEVIAGEPAAVDYQALPAAVF 361
Query: 382 TSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTH 441
T PE+G VG TE + +G G+F F A+ RA T EGFV++++ K T+ ++G
Sbjct: 362 TDPEIGTVGLTENEAANKGMTPVTGEFQFQASGRALTANRAEGFVRIIATKETERVIGAQ 421
Query: 442 IIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
I+GP ELI E E GA ED+ H HPT +EA+ EA
Sbjct: 422 IVGPEASELIAEIAAMIEMGAKLEDIGSTVHTHPTLSEAIMEA 464
>UniRef50_O84561 Cluster: Dihydrolipoyl dehydrogenase; n=9;
Chlamydiales|Rep: Dihydrolipoyl dehydrogenase -
Chlamydia trachomatis
Length = 465
Score = 329 bits (809), Expect = 9e-89
Identities = 179/458 (39%), Positives = 268/458 (58%), Gaps = 12/458 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D VVIG+GPGGYVAAI AAQ G+K +EK GGTCLN GCIPSKALL + + +
Sbjct: 6 DCVVIGAGPGGYVAAITAAQAGLKTALIEKREA-GGTCLNRGCIPSKALLAGAEVVTQIR 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
H Q GI + ++ M++ K + V+ + G+ L + NK+ + G G++++ +V+
Sbjct: 65 HA-DQFGIHVEGFSINYPAMVQRKDSVVRSIRDGLNGLIRSNKITVFSGRGSLISSTEVK 123
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTF--DEKQIITSTGALSLESVPKKMLVIGAG 210
+ GE + +I++A+GSE FPG+ F + +I+ STG L+L+ +P+KM +IG G
Sbjct: 124 ILGENP-SVIKAHSIILATGSEPRAFPGIPFSAESPRILCSTGVLNLKEIPQKMAIIGGG 182
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
VIG E S++ LG++V+ IE + I + + +++KT+ ++QG++F L V ++
Sbjct: 183 VIGCEFASLFHTLGSEVSVIEASSQILALN-NPDISKTMFDKFTRQGLRFVLEASVSNIE 241
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
G +++ + GN E + D VL+SIGRR T+ +GLDK G+ D+RG IP +
Sbjct: 242 DIGDRVRLTIN----GNVE--EYDYVLVSIGRRLNTENIGLDKAGVICDERGVIPTDATM 295
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVG 390
+T VP IYAIGD+ LAH A +GI+ I G +Y A+PSVI+T PEV VG
Sbjct: 296 RTNVPNIYAIGDITGKWQLAHVASHQGIIAARNIAGHKEEIDYSAVPSVIFTFPEVASVG 355
Query: 391 KTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGEL 450
+ +++ KV KFPF A +A GE +GF ++S +TT ILG ++IGP L
Sbjct: 356 LSPTAAQQQKIPVKVTKFPFRAIGKAVAMGEADGFAAIISHETTQQILGAYVIGPHASSL 415
Query: 451 INEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAA 488
I+E LA + HAHPT AE E+ L A
Sbjct: 416 ISEITLAVRNELTLPCIYETIHAHPTLAEVWAESALLA 453
>UniRef50_Q8R9D9 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Thermoanaerobacter|Rep: Dihydrolipoyl dehydrogenase -
Thermoanaerobacter tengcongensis
Length = 451
Score = 328 bits (807), Expect = 2e-88
Identities = 182/463 (39%), Positives = 277/463 (59%), Gaps = 17/463 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D++V+G GPGGY AAI+ ++LG KV +E+D +LGGTCLN GCIP+K H + L K
Sbjct: 4 DVIVVGGGPGGYTAAIRLSELGKKVALIEED-SLGGTCLNRGCIPTKVYAHAAELVTRIK 62
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ K GI T E T D K+ + K VK L GG+ L + ++++ G GT + N VE
Sbjct: 63 -EAKDFGI-TAEYTLDIAKLRQKKERVVKRLVGGVGYLMNLHHIDVINGKGTFIDKNTVE 120
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVI 212
V+G K +N +IA+GS+V P D + ++TS AL LE +P+K+++IGAG+I
Sbjct: 121 VNGAK----YTAENFIIATGSKVFLPPIEGIDLEGVMTSDKALELEKIPEKIVIIGAGII 176
Query: 213 GLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKE 272
GLE ++Y LG+ V IE L + + +D +V ++K L KQ ++ L +KV +++
Sbjct: 177 GLEFANIYASLGSKVIMIEMLPQLLPM-LDRDVVGVMEKALKKQKIELHLNSKVEKIERG 235
Query: 273 GSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQT 332
I + GN+E ++CD VL+++GR P G+ D + + ++ RG I V++ +T
Sbjct: 236 LRVIYTE-----NGNQESVECDAVLVAVGRVPNVNGV--DALNLEMNGRG-IKVDSHMRT 287
Query: 333 TVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGKT 392
++ IYAIGDV G LAH A +GIV I G + A+P+ +YT+PEV WVG
Sbjct: 288 SIENIYAIGDVTGGIQLAHVASYQGIVAAHNIAGEEKEADLTAVPNCLYTNPEVAWVGLN 347
Query: 393 EEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELIN 452
E +++ K+G FP+ A RA T GE++GFVK++++ ++G IIG G E+I+
Sbjct: 348 ESQAREKYGEVKIGTFPYTALGRAMTMGESDGFVKIIAEGKYGRVVGMEIIGAGATEIIH 407
Query: 453 EAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
E VLA + E++A HAHPT +E+++EA A G PIN
Sbjct: 408 EGVLAIKEEFTLEELADSIHAHPTLSESIKEAAEDAL-GMPIN 449
>UniRef50_Q6KCB6 Cluster: Dihydrolipoyl dehydrogenase; n=8;
Plasmodium|Rep: Dihydrolipoyl dehydrogenase - Plasmodium
falciparum
Length = 512
Score = 326 bits (801), Expect = 8e-88
Identities = 192/511 (37%), Positives = 285/511 (55%), Gaps = 27/511 (5%)
Query: 10 SPTFRSGSLVRIATRQYATTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGT 69
S FR+ + R ++T D++VIG GPGGYV +I+ AQ + V++V +D LGGT
Sbjct: 3 SVIFRAHCFFQPLRRCFSTKKGYDVIVIGGGPGGYVCSIRCAQNKLNVLNVNEDKKLGGT 62
Query: 70 CLNVGCIPSKALLHNSHLYHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAM 129
CLN GCIPSK+LLH SH Y+ AK FK+ GI V D + M ++K + L+ GI
Sbjct: 63 CLNRGCIPSKSLLHISHNYYEAKTRFKECGILVDNVKLDIETMHKHKNKCMGNLSDGINF 122
Query: 130 LFQKNKVNLVKGVGTIVAPNKVEVHGEKGVETVNTKNILIASGSEVTPFPG--------- 180
L++KN VN + G G++V + V + EK + V + I+IA+GS+ P
Sbjct: 123 LYKKNNVNHIIGHGSLVDEHTVLIKTEKEEKKVTAERIVIATGSKPIEIPLKKLNDNNFN 182
Query: 181 --------VTFDEKQIITSTGALSLESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEF 232
+ +D + I S L+ + VP + +IG GVIGLE+GSV+ +LG+DVT E+
Sbjct: 183 DADNVNDILEYDHEIIQNSDDILNFKKVPHNISIIGGGVIGLEIGSVFSKLGSDVTVFEY 242
Query: 233 LTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKEGSTIKVDVEAAKGGNKEVLD 292
+ G +D +V+K LQK L K MKF T V+G E + + + K +
Sbjct: 243 NERLCGF-LDADVSKVLQKTLEKIKMKFVFNTSVIGGNIENNQAALFAKNKKTNEIKKTT 301
Query: 293 CDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQTTV-PGIYAIGDVIHGPMLAH 351
++VLI IGR+ L L + I L+ +IPV+ F P I AIGD I GPMLAH
Sbjct: 302 SEIVLICIGRKANFDNLNLHLLNIELNKNKKIPVDEYFNVIAQPTIKAIGDAIDGPMLAH 361
Query: 352 KAEDEGIVC-------VEGIKGMPVHFNYDAIPSVIYTSPEVGWVGKTEEDLKKEGRAYK 404
KAE+EG + ++ K H NYD +PSVIYT PEV VG E K+ +K
Sbjct: 362 KAEEEGYLLANILFDELKNNKKKKAHINYDLVPSVIYTHPEVATVGYNEAKCKELNMNFK 421
Query: 405 VGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAA 464
FPF ANSR++T + +G +K++ +K T+ ILG+ IIG +LI + ++
Sbjct: 422 SVSFPFAANSRSRTIDDYDGLIKLIVEKDTNRILGSQIIGNNASDLILPLSIYVANNGSS 481
Query: 465 EDVARVCHAHPTCAEALREANLAAYSGKPIN 495
+ ++++ +AHPT +E ++E L ++ KPI+
Sbjct: 482 KSLSKIIYAHPTFSEVIKEVALQSFD-KPIH 511
>UniRef50_A1W7R7 Cluster: Dihydrolipoamide dehydrogenase; n=58;
Bacteria|Rep: Dihydrolipoamide dehydrogenase -
Acidovorax sp. (strain JS42)
Length = 627
Score = 326 bits (800), Expect = 1e-87
Identities = 194/490 (39%), Positives = 269/490 (54%), Gaps = 34/490 (6%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
+ D++V+G GPGGY AA +AA LG+ VV VE+ TLGG CLNVGCIPSKALLH + +
Sbjct: 130 ECDVLVLGGGPGGYSAAFRAADLGLNVVLVERYATLGGVCLNVGCIPSKALLHVAAVMDE 189
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
H K GI+ G + + +K + LTGG+A + + KV +++G G V N
Sbjct: 190 VSH-LKSAGIDFGAPQVNIHTLRGHKEKVIGKLTGGLAQMAKMRKVTVLRGYGHFVGANH 248
Query: 151 VEVHGEKGV--------ETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPK 202
+EV G + V K +IA+GS+ P + D+ +++ STGAL+L+ VPK
Sbjct: 249 LEVEETTGTSQDKTGAKKVVAFKRAIIAAGSQAVRLPFMP-DDPRVVDSTGALALKDVPK 307
Query: 203 KMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKL 262
+ML++G G+IGLE+G+VY LGA + +E L + G D ++ K QK+ + L
Sbjct: 308 RMLILGGGIIGLEMGTVYSTLGARLDVVEMLDGL-MQGADRDLVKVWQKMNQHRFDNVML 366
Query: 263 GTKVLGVKKEGSTIKVDVEAAKGG--NKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDD 320
TK + + IKV AK G E D+VL ++GR P K + DK G+A+ D
Sbjct: 367 NTKTVAAEATPEGIKVSFAPAKDGVTVPEPQVYDLVLQAVGRTPNGKKIAADKAGVAVTD 426
Query: 321 RGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKG--------MPVHFN 372
RG I V+ + +T VP I+AIGD++ PMLAHKA E V E I G FN
Sbjct: 427 RGFINVDIQMRTNVPHIFAIGDIVGQPMLAHKAVHEAHVAAEVIAGELQGNKELASAAFN 486
Query: 373 YDAIPSVIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDK 432
IPSV YT PEV WVG TE+ K +G K G FP+ A+ RA NG EGF K+L D
Sbjct: 487 ARVIPSVAYTDPEVAWVGLTEDQAKAQGIKVKKGLFPWAASGRAIANGRDEGFTKLLFDD 546
Query: 433 TTDV-------------ILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAE 479
+ + ILG ++G G++I E LA E GA A D+ + H HPT E
Sbjct: 547 SPEAGSGDGHAGRGHGKILGGGMVGTHAGDMIGEIALAIEMGADAVDIGKTIHPHPTLGE 606
Query: 480 ALREANLAAY 489
++ A A+
Sbjct: 607 SIGMAAEVAH 616
>UniRef50_A0L7L9 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Magnetococcus sp. MC-1|Rep: Dihydrolipoyl dehydrogenase
- Magnetococcus sp. (strain MC-1)
Length = 464
Score = 326 bits (800), Expect = 1e-87
Identities = 182/463 (39%), Positives = 272/463 (58%), Gaps = 6/463 (1%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL+VIG+GPGGY AAI+AAQLG+ V+ +EK P GGTCLN GCIP+KALL ++HLY +
Sbjct: 7 DLIVIGAGPGGYPAAIRAAQLGLSVLCIEKSPHPGGTCLNAGCIPTKALLASTHLYTQIR 66
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
GIE + + +M K V L GI LF+K V L+ + P ++
Sbjct: 67 DQADLHGIEITTMQVNLARMQGRKERVVSQLRSGILGLFKKYGVTLLHDEAIVSGPGQIT 126
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVI 212
+ ET+ K IL+A+G + + D + +ITS A++L VP+ ++VIG+G +
Sbjct: 127 LAASG--ETLQAKAILLATGGQPRRPASMPVDGQVVITSEQAIALTRVPEHLIVIGSGAV 184
Query: 213 GLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKE 272
GLEL S++ RLGA V+ IE I G D VA+T ++ L +QG+ F +V V +
Sbjct: 185 GLELASIWVRLGAQVSVIEAQPEI-LPGWDATVARTAKRSLRQQGITFLTDHRVETVVRS 243
Query: 273 GSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQT 332
GS V +K G +LD D VL+++GR+ G+ + + D++GR+ V+ + T
Sbjct: 244 GSRAAVTCLNSK-GETLMLDGDQVLVAVGRQAQLCVAGIQNLELQQDEQGRLWVDAHYAT 302
Query: 333 TVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGKT 392
++ G+YA+GD+I GP LAH+A EG+ + + G P+ IPSV+YT PE+ VG T
Sbjct: 303 SLAGLYAVGDLIAGPQLAHRATAEGLRVADYLAGRPLS-PMGPIPSVVYTDPELAMVGLT 361
Query: 393 EEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELIN 452
E+ K G A K G+FPF+A+ RA+ +TEG +K++ D+TT +LG H++G G E +
Sbjct: 362 EQQAKVAGYAVKCGQFPFMASGRARAQEQTEGLIKLVMDQTTGQLLGAHVVGGAGAEHLQ 421
Query: 453 EAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
A+ A + + R+ HP+ EAL EA L A + KPI+
Sbjct: 422 LAMAAMLTQDRGQLLERLVMPHPSFGEALHEAWLVA-TQKPIH 463
>UniRef50_Q0AVI0 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
Dihydrolipoyl dehydrogenase - Syntrophomonas wolfei
subsp. wolfei (strain Goettingen)
Length = 462
Score = 322 bits (790), Expect = 2e-86
Identities = 181/458 (39%), Positives = 261/458 (56%), Gaps = 16/458 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYH-MA 91
DL+VIG GPGGYVAAI+A QLGMKV VEKD LGGTCLN GCIP+K ++ + +
Sbjct: 3 DLLVIGGGPGGYVAAIRARQLGMKVALVEKDK-LGGTCLNRGCIPTKTYYRHAEIMRSLQ 61
Query: 92 KHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
+ D ++ D K V+ + GG+A L Q + V +++G + P +V
Sbjct: 62 RLDEFCIQLDAEPARLDMAGTRARKDAVVEQMAGGVADLLQAHGVEVIRGEAVVEEPGRV 121
Query: 152 EVHGEKGVETVNTKNILIASGSE-VTP--FPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
V G E++ + +LIA+GSE + P PG ++T L ++P ++L+IG
Sbjct: 122 RV----GEESIRAERLLIATGSESIRPAALPGAALPG--VLTCEELLERSAIPGRLLIIG 175
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
GVIG+E ++Q G+ VT +E L +D E+A+ + + +QG++ K G KV
Sbjct: 176 GGVIGMEFACIFQAFGSQVTVLESLPRALAF-LDQEIARRMSVLFKRQGIEIKTGAKVES 234
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
+ + + + KG + + D+VL+++GR P T GL L+K+G+ + +G I VN
Sbjct: 235 INTQDDHLLITASDKKGNVQ--YEADLVLLAVGRSPVTAGLNLEKLGVETE-QGFIKVNQ 291
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGW 388
++++V GIYAIGDVI PMLAH A +EG V VE + GM NY+AIP I+T PE+
Sbjct: 292 DYESSVGGIYAIGDVIGPPMLAHVASEEGRVAVERMAGMDSRLNYEAIPHCIFTFPEIAA 351
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VG T+E+ G K+GKF F AN +A GE+EG +KV+ D +LG HIIGP
Sbjct: 352 VGLTQEEAAPRGIDCKIGKFQFAANGKAVAMGESEGLIKVIC-SPDDTVLGVHIIGPHAS 410
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANL 486
+LI EA L G E+ + H HPT E L EA L
Sbjct: 411 DLILEASLLVNLGMKVEEALHMVHPHPTLGETLYEALL 448
>UniRef50_Q8F290 Cluster: Dihydrolipoyl dehydrogenase; n=4;
Leptospira|Rep: Dihydrolipoyl dehydrogenase - Leptospira
interrogans
Length = 490
Score = 319 bits (783), Expect = 1e-85
Identities = 182/472 (38%), Positives = 261/472 (55%), Gaps = 15/472 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL VIG+GPGGYVAAI+AAQLGM V +EKD GG CLN GCIP+KALL ++HL
Sbjct: 24 DLTVIGAGPGGYVAAIRAAQLGMNVCIIEKDKP-GGICLNWGCIPTKALLESAHLLEKL- 81
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
H K+ GI + DF ++ N G+ G+ L KNK+ KG PN +
Sbjct: 82 HSAKEYGINLSDPKPDFAAIIRRSRNVADGMASGVEFLLNKNKITRKKGTAVFKDPNTIW 141
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVI 212
+ + E + +K ++A+G+ PG+ FD +++S A+ + +P+ +L++GAG I
Sbjct: 142 LP-DSSKEEITSKYFILATGARARELPGLPFDSHTVLSSKTAMIQDKIPESLLIVGAGAI 200
Query: 213 GLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKE 272
G+E Y +G VT +E + I V D E++ L+K K+G++ G V K
Sbjct: 201 GVEFADFYSTMGTKVTLVEMMDQILPVE-DKEISTFLEKSFVKRGIRVLTGVGVSDPKIV 259
Query: 273 GSTIKVDVEAAKGGNK-EVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQ 331
+KV ++ E + + +L+SIG P T + L+++GI L +G + + K++
Sbjct: 260 NGKVKVLLKGKNLPEAVESFEAEKILVSIGLVPNTDSMHLEEIGIFLQ-KGFVKTDTKYK 318
Query: 332 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIK---GMPVHFNY-----DAIPSVIYTS 383
T+VP IYAIGD P+LAH A EGI VE I G P H +Y +AIP Y
Sbjct: 319 TSVPHIYAIGDCNGPPLLAHVASMEGIKAVEAISIHAGNPHHLSYIPIDYNAIPGCTYCH 378
Query: 384 PEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHII 443
PEV +G TE+ G VGKFPF+A+ RAK G+T GF KV+ DKT+ ILG H+I
Sbjct: 379 PEVASIGFTEKKATDMGYTISVGKFPFVASGRAKAMGDTGGFTKVIVDKTSGEILGAHLI 438
Query: 444 GPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
GPG EL+ L A+++A AHPT +E + E + A G+ IN
Sbjct: 439 GPGVTELLPAVSLGITQELTAKEIASTIFAHPTLSETVME-SFGAALGEAIN 489
>UniRef50_P57303 Cluster: Dihydrolipoyl dehydrogenase; n=10;
Bacteria|Rep: Dihydrolipoyl dehydrogenase - Buchnera
aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon
pisumsymbiotic bacterium)
Length = 473
Score = 318 bits (780), Expect = 3e-85
Identities = 172/448 (38%), Positives = 259/448 (57%), Gaps = 4/448 (0%)
Query: 34 LVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAKH 93
+VVIGSGP GY AA + A LG+ V +E+ LGG CLNVGCIPSK LLH + + AK
Sbjct: 9 VVVIGSGPAGYSAAFRCADLGLDTVLIERYDKLGGVCLNVGCIPSKTLLHIAKVIKEAK- 67
Query: 94 DFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVEV 153
+ + G+ + D KK+ +K + V LT G++ + +K K+ + +G + V
Sbjct: 68 ELHKTGVSFNKPDIDIKKIKNWKQHIVNKLTDGLSSMRKKRKIRIFQGHAIFETDKSLCV 127
Query: 154 HGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVIG 213
+ T+ N +IA+GS+ P + D+ +I ST ALSL+ +P L+IG+G+IG
Sbjct: 128 TNTEDKFTIFFDNAIIATGSKPIKIPSIPHDDIRIWDSTDALSLKKIPNNFLIIGSGIIG 187
Query: 214 LELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKEG 273
LE+ ++Y LG+ V I+ V ID +++ +K +++Q L T + V+ +
Sbjct: 188 LEMATIYSALGSKVDIIDRFNHFLPV-IDEDISSIYKKSINQQ-FNLMLNTHIDKVEVKK 245
Query: 274 STIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQTT 333
+ VD+ K +L D VL++IGR P LGLD++G+ +++ G I VNN+ +T
Sbjct: 246 DALIVDMIHENIPKKNIL-YDAVLVAIGRTPNIDSLGLDRIGLKINNFGFIQVNNQLKTN 304
Query: 334 VPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGKTE 393
+P IYAIGDV PMLAHK EG + E I G +F IPS+ YT PE+ WVG +E
Sbjct: 305 IPHIYAIGDVAGTPMLAHKGVHEGHIAAEVISGKNHYFEPKVIPSIAYTDPEIAWVGLSE 364
Query: 394 EDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELINE 453
++ K+E Y+V FP+ A+ RA + + G K++ +K + I+G I+G GELI E
Sbjct: 365 KEAKQENINYEVAIFPWNASGRAIASNCSIGKTKLIFNKQNNKIIGGSIVGSNAGELIGE 424
Query: 454 AVLAQEYGAAAEDVARVCHAHPTCAEAL 481
LA E G AED+A HAHPT +E++
Sbjct: 425 VGLAIEMGCDAEDIALTIHAHPTLSESI 452
>UniRef50_A4FLD8 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Bacteria|Rep: Dihydrolipoyl dehydrogenase -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 491
Score = 317 bits (778), Expect = 5e-85
Identities = 181/484 (37%), Positives = 261/484 (53%), Gaps = 25/484 (5%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D++VIG GPGGYVAAI+AAQ G+ V VEK+ T GG CLN GCIP+KA+L ++ +Y
Sbjct: 5 DVLVIGGGPGGYVAAIRAAQRGLSVGVVEKERT-GGVCLNWGCIPTKAMLRSAEVYETVL 63
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
H G++ V+ D+ + K VKGLT G+A L + N V ++ G P ++
Sbjct: 64 H-AADYGVQAENVSLDYDAVSRRKDGIVKGLTDGVASLLKANGVTVIYGHARFTGPTTLD 122
Query: 153 VH-------------------GEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTG 193
V+ G++ VE V ++++IA+GS P D +ITS G
Sbjct: 123 VYAVGESALGAGGPKYAADPTGDQPVEQVKARDVIIATGSVPVQLPLPGADLPGVITSDG 182
Query: 194 ALSLESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKIL 253
A L VPK++ VIG +G E S++ GA+VT IE ++ D E+ K L +
Sbjct: 183 AFGLTEVPKRIAVIGGSAVGAEWASLFNTFGAEVTIIEMQPTLVPAE-DAEIGKALGRSF 241
Query: 254 SKQGMKFKLGTKVLGVKKEGSTIKVDVEAAKGGNK-EVLDCDVVLISIGRRPYTKGLGLD 312
K G+ G+ V ++ G ++ G K + +D DVVL+ +GR+P T L L+
Sbjct: 242 GKAGINVLTGSTVSKIESAGRGKNAGLKVFVDGPKAQEIDADVVLVGVGRKPNTAALDLE 301
Query: 313 KVGIALDDRGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMP-VHF 371
K G+A D RG +PV+ + +T V +YAIGDV +LAH A +G+ E I G
Sbjct: 302 KAGVATDARGFVPVDEQLRTNVEHVYAIGDVTGRVLLAHVASHQGVTAAEVIAGSDHARM 361
Query: 372 NYDAIPSVIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSD 431
+YD IP+ +T PE+ VG TE + G GKFPF A R KT G ++GF+K+++
Sbjct: 362 DYDVIPAATFTHPEIASVGLTEAQAVEAGHEVVTGKFPFAAIGRTKTYGNSDGFMKIVAG 421
Query: 432 KTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 491
K +LG HIIG +LI E LA A +++A HAHPT E EA ++A G
Sbjct: 422 KQYGEVLGVHIIGQSASDLITEGALAINLEATLDELAETVHAHPTLGEIGMEAAMSAL-G 480
Query: 492 KPIN 495
PI+
Sbjct: 481 LPIH 484
>UniRef50_A0M205 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Bacteria|Rep: Dihydrolipoyl dehydrogenase - Gramella
forsetii (strain KT0803)
Length = 473
Score = 316 bits (776), Expect = 9e-85
Identities = 178/463 (38%), Positives = 263/463 (56%), Gaps = 8/463 (1%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
+L++IG+GPGGY AA +AA LG+KV ++ + GG CL GCIPSKALLH + + A
Sbjct: 8 ELIIIGAGPGGYAAAFRAADLGLKVTLIDPEANPGGVCLYRGCIPSKALLHIAKVKQEAM 67
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ GIE D KK+ ++K + V+ LT G+ L + K++ +KG ++ K++
Sbjct: 68 QA-AEWGIEFESPKIDLKKLQKWKDSVVEKLTDGLGQLSKSKKIDYIKGTAEFISDKKIK 126
Query: 153 VHG-EKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGV 211
V+ E+ + +N+++++GS PG+ D K++I S AL L +PK MLVIG G
Sbjct: 127 VNPVEEDPYELEFENLILSTGSVNVSLPGIEIDHKKVIDSKDALDLNKIPKSMLVIGGGY 186
Query: 212 IGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKK 271
IGLELGSVY LG+ V+ E +TS G D ++ +K + + F TKV
Sbjct: 187 IGLELGSVYAALGSKVSVAE-MTSGFLPGADRDLVNVFEKEHPFEALYFD--TKVEKASV 243
Query: 272 EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQ 331
+ +K ++ KE D +L+++GR+P TK L L+ I D+ G + VN + Q
Sbjct: 244 TKNKVKATLKGKDDKTKEKT-FDQILVAVGRKPNTKTLALNMANIEPDENGFLKVNRQRQ 302
Query: 332 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMP-VHFNYDAIPSVIYTSPEVGWVG 390
T IYAIGD+ P+LAHKA EG V VE I G ++ +IP++++T+P++ W G
Sbjct: 303 TKKKNIYAIGDLTGEPLLAHKATYEGKVAVETIAGEKGAAYDPKSIPAIVFTNPQMAWCG 362
Query: 391 KTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGEL 450
T+E+ KK KV KFP+ A+ RA G G +++ DK T ILG + G G L
Sbjct: 363 LTQEEAKKNNIEIKVLKFPWSASGRAVAVGNPNGVTRLIVDKKTGRILGGGVAGKNAGSL 422
Query: 451 INEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKP 493
I+E LA E A AED+A H HPT +E + EA +SG P
Sbjct: 423 ISEISLAIEMAATAEDIALSIHPHPTLSETIMEA-AEIFSGSP 464
>UniRef50_Q8K9T7 Cluster: Dihydrolipoyl dehydrogenase; n=33;
Gammaproteobacteria|Rep: Dihydrolipoyl dehydrogenase -
Buchnera aphidicola subsp. Schizaphis graminum
Length = 476
Score = 316 bits (776), Expect = 9e-85
Identities = 168/454 (37%), Positives = 262/454 (57%), Gaps = 3/454 (0%)
Query: 32 ADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMA 91
+++V+IGSGP GY AA + A LG++ V +E LGG CLNVGCIPSK+LLH + + A
Sbjct: 7 SEVVIIGSGPAGYSAAFRCADLGLETVLIEHQERLGGVCLNVGCIPSKSLLHIAKIIKDA 66
Query: 92 KHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
+ + G+ + D KK+ +K +K LT G++ + +K KV +V+G + V
Sbjct: 67 S-ELSESGVFFNKPIIDIKKINNWKEKIIKKLTTGLSNMGEKRKVRIVQGKALFNTDHSV 125
Query: 152 EVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGV 211
V +K T+ K+ +IA+GS+ P + ++ +I ST ALSL+S+P + L+IG G+
Sbjct: 126 LVKNKKNDFTIFFKHAIIATGSKPIKIPSLPNEDNRIWNSTDALSLKSIPNRFLIIGGGI 185
Query: 212 IGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKK 271
IGLE+ ++Y LG+ V ++ + +D ++ K + K+ K L T V V+K
Sbjct: 186 IGLEMATIYSALGSKVDIVDRFNAFLP-SVDKDITDIYIKSIKKR-FKLLLNTHVKSVEK 243
Query: 272 EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQ 331
+ A + ++ V D +L++IGR P LGL+K+G+ L++ G I +N + +
Sbjct: 244 SKDNDLIVKIAEENSDENVCCYDNILVAIGRSPNVDFLGLEKIGLKLNESGFIEINQQLK 303
Query: 332 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGK 391
T + IYAIGDV PMLAHKA + + E I G +F IPSV YT PE+ WVG
Sbjct: 304 TNISHIYAIGDVTGFPMLAHKAVQQAHIAAEVISGKKHYFEPKVIPSVAYTDPEIAWVGL 363
Query: 392 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 451
+E++ + Y+V FP+ A+ RA + T G K++ +K T+ I+G IIG ELI
Sbjct: 364 SEKEAENNDIDYEVSLFPWSASGRAHASNCTLGMTKLIFNKNTNKIIGGSIIGTNASELI 423
Query: 452 NEAVLAQEYGAAAEDVARVCHAHPTCAEALREAN 485
+E LA E G+ AED++ H HPT +E++ A+
Sbjct: 424 SEIGLAIEMGSDAEDISLTIHPHPTLSESISLAS 457
>UniRef50_Q8VPK7 Cluster: Dihydrolipoamide dehydrogenase; n=43;
Streptococcus|Rep: Dihydrolipoamide dehydrogenase -
Streptococcus pneumoniae
Length = 567
Score = 315 bits (774), Expect = 2e-84
Identities = 191/455 (41%), Positives = 255/455 (56%), Gaps = 18/455 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+VVIG GP GYVAAIKAAQ G KV VEK LGGTCLN GCIP+K LHN+ +
Sbjct: 113 DIVVIGGGPAGYVAAIKAAQFGGKVALVEKSE-LGGTCLNRGCIPTKTYLHNAEIIENIG 171
Query: 93 HDFKQRGI--ETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
H RGI E T D +K++E K+ V L GG+A L + V + KG+GTI
Sbjct: 172 HA-ANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGTITKDKN 230
Query: 151 VEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
V V+G E + TK I++A GS+V + ++TS L + VP+ +++IG G
Sbjct: 231 VLVNGS---ELLETKKIILAGGSKVNKINVPGMESPLVMTSDDILEMNEVPESLVIIGGG 287
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
V+G+ELG + G+ VT IE + I +D EV+K L+ IL ++GM GTK+ +
Sbjct: 288 VVGIELGQAFMTFGSKVTVIEMMDRIVPA-MDVEVSKNLRLILERKGMTILTGTKLQEII 346
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
+E +++ VE K+ + L+SIGR P +G+G +V LD RG I V
Sbjct: 347 EENGQLRIKVEG-----KDDIIASKALLSIGRMPDLEGIG--EVEFELD-RGCIKVTEYM 398
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEG-IKGMPVHFNYDAIPSVIYTSPEVGWV 389
+T+VPGIYA GD+ MLAH A G V E +KG + P+ IYT PEV V
Sbjct: 399 ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVAAV 458
Query: 390 GKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGE 449
G TEE + E +GKF F AN RA + +GFVKV++DK ILG HIIGP E
Sbjct: 459 GLTEEQAR-EKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPAAAE 517
Query: 450 LINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
LINEA E E++ + H HPT +E + EA
Sbjct: 518 LINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEA 552
>UniRef50_Q1GHN7 Cluster: Dihydrolipoyl dehydrogenase; n=41;
Bacteria|Rep: Dihydrolipoyl dehydrogenase - Silicibacter
sp. (strain TM1040)
Length = 464
Score = 315 bits (774), Expect = 2e-84
Identities = 172/458 (37%), Positives = 261/458 (56%), Gaps = 7/458 (1%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D++VIG+GPGGYVAAI+A+QLG+K VE++ LGG CLN GCIP+KALL +S ++H+ +
Sbjct: 7 DVIVIGAGPGGYVAAIRASQLGLKTCVVEREH-LGGICLNWGCIPTKALLRSSEVFHLME 65
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
K G++ + +D +++ K L+ G+ L +K+K++++ G T+ A KV
Sbjct: 66 RA-KDFGLKAENIGYDLGAVVKRSRGVAKQLSSGVKGLLKKHKIDVIMGEATLPAKGKVA 124
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVI 212
V +KG E + KNI++A+G+ PG+ D + T AL + +PKK+LVIG+G I
Sbjct: 125 VKTDKGSEELTGKNIILATGARARELPGLEADGDLVWTYKHALDPKRMPKKLLVIGSGAI 184
Query: 213 GLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKE 272
G+E S Y LGAD T +E + + V D E++K +K KQGMK V + +
Sbjct: 185 GIEFASFYNTLGADTTVVEVMERVLPVE-DEEISKFAKKAFEKQGMKIMQKAMVKQLDRA 243
Query: 273 GSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQT 332
+ +E GG E + D V+ ++G +GLGL+ +G+ + DR + + +T
Sbjct: 244 SGKVTAHIEV--GGKVEKHEFDTVISAVGIVGNVEGLGLEGLGVKI-DRTHVITDEYCRT 300
Query: 333 TVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH-FNYDAIPSVIYTSPEVGWVGK 391
V G+YAIGD+ P LAHKA EG++ E I G H ++I Y P+V VG
Sbjct: 301 GVDGLYAIGDIAGAPWLAHKASHEGVMVAELIAGKHAHPVKPESIAGCTYCHPQVASVGY 360
Query: 392 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 451
TE K+ G KVG+FPF+ N +A GE EG +K + D+ T +LG H+IG ELI
Sbjct: 361 TEAKAKELGYKVKVGRFPFIGNGKAIALGEPEGLIKTVFDEKTGELLGAHMIGAEVTELI 420
Query: 452 NEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAY 489
V+ ++ ED+ HPT +E + E+ L A+
Sbjct: 421 QGYVVGRQLETTEEDLMNTVFPHPTLSEMMHESVLDAF 458
>UniRef50_Q834J0 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Lactobacillales|Rep: Dihydrolipoyl dehydrogenase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 469
Score = 314 bits (770), Expect = 5e-84
Identities = 186/468 (39%), Positives = 265/468 (56%), Gaps = 21/468 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL+++G G GGYVAAI+AAQ G+ V VEK LGGTCL+ GCIP+KALL ++ ++ K
Sbjct: 6 DLLILGGGTGGYVAAIRAAQKGLNVTIVEKYK-LGGTCLHKGCIPTKALLRSAEVFDTLK 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
GIET + DF K+ + K ++ L G+ L +KNK+ ++ G G I+ P+
Sbjct: 65 QA-ASFGIETEAASIDFSKIQQRKEGIIEQLHKGVEGLCKKNKIKILAGEGAILGPSIFS 123
Query: 153 -VHGEKGV---------ETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPK 202
V G V E + KN++IA+GS P + DE+ I++S G L LE +P+
Sbjct: 124 PVSGAVAVTFNDPTREEEIIVPKNVIIATGSSSKTLPNLPLDEEFILSSDGMLELEELPE 183
Query: 203 KMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKL 262
+ +IG GVIG+E S+ LG +VT IEFL + + ++K L+K L ++G+ L
Sbjct: 184 SIAIIGGGVIGVEWASLLNSLGVNVTIIEFLDRLL-INESATISKELKKRLEQRGINILL 242
Query: 263 GTKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRG 322
G+KV K G ++V+V +E L D V+++IGR+P LGL + D+G
Sbjct: 243 GSKVQEAKVTGQKVQVEV-----AGQETLTVDKVMVAIGRQPNINKLGLQNTSVKYTDKG 297
Query: 323 RIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH-FNYDAIPSVIY 381
I VN +QTT IYAIGD I LAH A EG + V+ + G V NY +P +Y
Sbjct: 298 -IEVNEFYQTTEGHIYAIGDCIDTLQLAHVAMKEGELAVQHLLGETVEPLNYTNVPRGVY 356
Query: 382 TSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTH 441
T+PE+ VG T E L E + +G F F N ++ GET+GF++V+ DK TD +LG
Sbjct: 357 TNPEIASVGYTRETLPAE-KEVVIGTFNFNGNGKSLVYGETDGFIEVIRDKKTDDLLGVS 415
Query: 442 IIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAY 489
+IGP +LI EA A AA ++ HAHPT E L+EA L Y
Sbjct: 416 MIGPHVTDLIAEASTAMYLDAAPIEIGEAIHAHPTMTEVLQEAALDTY 463
>UniRef50_Q50068 Cluster: Dihydrolipoyl dehydrogenase; n=33;
Actinomycetales|Rep: Dihydrolipoyl dehydrogenase -
Mycobacterium leprae
Length = 467
Score = 312 bits (767), Expect = 1e-83
Identities = 186/470 (39%), Positives = 256/470 (54%), Gaps = 13/470 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+VV+G+GPGGYVAAI+AAQLG+ VE GG CLNVGCIPSK LLHN+ L H+
Sbjct: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAVVEPK-YWGGICLNVGCIPSKVLLHNAELAHIFT 63
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ K GI +G+ +FD+ + +G G+ L +KNK+ + G G N +
Sbjct: 64 KEAKTFGI-SGDASFDYGIAYDRSRKVSEGRVAGVHFLMKKNKITEIHGYGRFTDANTLS 122
Query: 153 VHGEKGV-ET---VNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
V +GV ET V N++IA+GS+ PG T +IT + +P ++++G
Sbjct: 123 VELSEGVPETPLKVTFNNVIIATGSKTRLVPG-TLLSTNVITYEEQILTRELPDSIVIVG 181
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
AG IG+E G V + G DVT +EFL D EV+K ++K K G+K GTKV
Sbjct: 182 AGAIGIEFGYVLKNYGVDVTIVEFLPR-AMPNEDAEVSKEIEKQFKKMGIKILTGTKVES 240
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
+ GS + V V +K G + L D VL +IG P G GLDKVG+AL + +++
Sbjct: 241 ISDNGSHVLVAV--SKDGQFQELKADKVLQAIGFAPNVDGYGLDKVGVALTADKAVDIDD 298
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHF--NYDAIPSVIYTSPEV 386
QT V IYAIGDV LAH AE +G+V E I G +Y +P + P V
Sbjct: 299 YMQTNVSHIYAIGDVTGKLQLAHVAEAQGVVAAEAIAGAETLALSDYRMMPRATFCQPNV 358
Query: 387 GWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPG 446
G TE+ + G V KFPF AN++A G+ GFVK+++D +LG H+IG
Sbjct: 359 ASFGLTEQQARDGGYDVVVAKFPFTANAKAHGMGDPSGFVKLVADAKYGELLGGHMIGHN 418
Query: 447 GGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 496
EL+ E LAQ++ A ++ R H HPT +EAL+E G INF
Sbjct: 419 VSELLPELTLAQKWDLTATELVRNVHTHPTLSEALQEC-FHGLIGHMINF 467
>UniRef50_Q92Q96 Cluster: Dihydrolipoyl dehydrogenase; n=15;
Alphaproteobacteria|Rep: Dihydrolipoyl dehydrogenase -
Rhizobium meliloti (Sinorhizobium meliloti)
Length = 481
Score = 312 bits (766), Expect = 1e-83
Identities = 189/481 (39%), Positives = 273/481 (56%), Gaps = 24/481 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D++V+GSGPGGYV AI++AQLG+K VE++ LGG CLN GCIP+KALL ++ + A
Sbjct: 6 DVIVVGSGPGGYVTAIRSAQLGLKTAIVEREH-LGGICLNWGCIPTKALLRSAEILDHAN 64
Query: 93 HDFKQRGIET-GEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGV------GTI 145
H K G+ G++T + K ++ L GG+A L +KNKV+++ G G I
Sbjct: 65 HA-KNYGLTLEGKITANVKDVVARSRGVSARLNGGVAFLMKKNKVDVIWGEAKLTKPGEI 123
Query: 146 V--APNKVEVH-------GEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALS 196
V AP+K V G KG T K+I++A+G+ PG+ D K I T A+
Sbjct: 124 VVGAPSKPAVQPQNPVPKGVKGEGTYTAKHIIVATGARPRALPGIEPDGKLIWTYFEAMK 183
Query: 197 LESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQ 256
E PK +LV+G+G IG+E S Y+ +G DVT +E L I V D E++ +K L K+
Sbjct: 184 PEEFPKSLLVMGSGAIGIEFASFYRSMGVDVTVVELLPQIMPVE-DAEISAFARKQLEKR 242
Query: 257 GMKFKLGTKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGI 316
G+K KV V+K + + VE K G + D ++ ++G + + LGL+ +G+
Sbjct: 243 GLKIITDAKVTKVEKGANDVTAHVET-KDGKVTPIKADRLISAVGVQGNIENLGLEALGV 301
Query: 317 ALDDRGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMP-VH-FNYD 374
D RG I + +T V GIYAIGDV PMLAHKAE EG++CVE I G+P VH +
Sbjct: 302 KTD-RGCIVTDGYGKTNVAGIYAIGDVAGPPMLAHKAEHEGVICVEKIAGVPGVHALDKG 360
Query: 375 AIPSVIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTT 434
IP Y P+V VG TE K+ GR +VG++ F AN +A GE +G +K + DK T
Sbjct: 361 KIPGCTYCDPQVASVGLTEAKAKELGRDIRVGRYSFGANGKAIALGEDQGLIKTIFDKKT 420
Query: 435 DVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPI 494
++G H++G ELI V+A E++ HPT +E ++E+ L AY G+ +
Sbjct: 421 GELIGAHMVGAEVTELIQGFVVAMNLETTEEELMHTVFPHPTLSEMMKESVLDAY-GRVL 479
Query: 495 N 495
N
Sbjct: 480 N 480
>UniRef50_Q9KG96 Cluster: Dihydrolipoyl dehydrogenase; n=1; Bacillus
halodurans|Rep: Dihydrolipoyl dehydrogenase - Bacillus
halodurans
Length = 473
Score = 311 bits (763), Expect = 3e-83
Identities = 171/460 (37%), Positives = 253/460 (55%), Gaps = 7/460 (1%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
+ D VV+G GPGGY AAI+ QLG VV +EK+ LGG CLN GCIPSKAL+ + +
Sbjct: 9 EVDTVVVGGGPGGYTAAIRLGQLGKSVVLIEKNQ-LGGVCLNRGCIPSKALIQMAEKFDE 67
Query: 91 AKHDFKQRGIET-GE-VTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAP 148
H K+ G+E G+ + D K ++K L GI L Q+N V +V G ++
Sbjct: 68 LTH-LKEMGVELPGKPASIDLHKWQKWKQEITTKLNTGIHQLCQQNGVTVVTGEAHFLSS 126
Query: 149 NKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
++V V + ++ ++A+GS P D I+ ST AL L VP+ + ++G
Sbjct: 127 HRVGVETGNAFDVYKFEHAIVATGSSPRSLPFAEVDHTYILDSTSALELTEVPRSLSIVG 186
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
G IG+ELG + +LG+ VT +E I + L K K G+ K T V
Sbjct: 187 GGYIGMELGLAFAKLGSAVTIVEMSPHILPATAPHISREVLNKA-EKLGVTIKSSTSVEH 245
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
+ +++ V++ G +E L + L+++GR P TKGLGL++VG+ ++ G +P+N
Sbjct: 246 LTVNDGYVELIVQS--NGEQETLQSEKALMTVGRSPNTKGLGLEQVGVFFNEDGTLPINE 303
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGW 388
+ +T + I+AIGDV GP LAHKA +GIV E I G+P + IP V++T P++
Sbjct: 304 ECRTNIDHIFAIGDVTEGPALAHKASKQGIVAAEVIGGLPSAIDSSYIPYVVFTDPQIAG 363
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VG T + +++G K +FPF AN A + +GF +V+ D+ + ++LG HI+G
Sbjct: 364 VGLTAKQAQEQGHRVKTARFPFQANGLALVASKPDGFAEVIVDEESHLLLGFHIVGADAS 423
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAA 488
LI E VLA E GA EDVA H HPT +E A AA
Sbjct: 424 NLIGEGVLALELGARVEDVALTVHPHPTFSEGWLGAAEAA 463
>UniRef50_Q68VU4 Cluster: Dihydrolipoyl dehydrogenase; n=11;
Rickettsiales|Rep: Dihydrolipoyl dehydrogenase -
Rickettsia typhi
Length = 459
Score = 310 bits (761), Expect = 6e-83
Identities = 183/458 (39%), Positives = 256/458 (55%), Gaps = 10/458 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+ VIG GPGGYVAAI+AAQL KVV +EK LGG CLN GCIP+K+LL ++ ++ K
Sbjct: 5 DVAVIGGGPGGYVAAIRAAQLKKKVVLIEKSH-LGGVCLNWGCIPTKSLLKSAEVFEYIK 63
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
H K GI+ G + +K++E L G+ +L +KNKV ++ GV + NKV
Sbjct: 64 HA-KDYGIDVGIAEINIQKIVERSREIASTLACGVQLLLKKNKVTIINGVASF-GENKVI 121
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVI 212
+K TV NI+IA+G+ G D QI TS A+ + VPK M++IG+G I
Sbjct: 122 NVNDK--PTVKANNIIIATGARPKILQGFEPDITQIWTSKEAMIPQYVPKSMIIIGSGAI 179
Query: 213 GLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKE 272
G+E S Y +G DVT IE I D E+A KI ++G+K K+ +K+
Sbjct: 180 GIEFASFYNSIGVDVTIIEAYNRILP-SEDTEIAGIAHKIFEQKGIKILTNAKL--IKQT 236
Query: 273 GSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQT 332
S K++VE G K+ L ++L+++G + LGL+K + +++ G I N QT
Sbjct: 237 KSQNKIEVELELEGKKQKLQATILLMAVGITANIENLGLEKTKVQVEN-GYIVTNGLMQT 295
Query: 333 TVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGM-PVHFNYDAIPSVIYTSPEVGWVGK 391
GIYAIGDV P LAHKA EGI+ E I G+ P N IP IY+SP++ VG
Sbjct: 296 AESGIYAIGDVSGVPCLAHKASHEGIIAAESIAGLKPNSINKHNIPYCIYSSPQIASVGL 355
Query: 392 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 451
TEE K G K+G+FPF AN +A +G + G +K + D T +LG H+IG ELI
Sbjct: 356 TEEVAKDLGYEIKIGRFPFRANGKALVSGNSYGLIKTIFDVKTGELLGAHMIGLEVTELI 415
Query: 452 NEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAY 489
V+++ D+ HPT +E + E+ LAAY
Sbjct: 416 QGYVVSKNLEGTELDLIHTIFPHPTLSEMMHESVLAAY 453
>UniRef50_Q1FMM1 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Clostridiaceae|Rep: Dihydrolipoyl dehydrogenase -
Clostridium phytofermentans ISDg
Length = 470
Score = 308 bits (757), Expect = 2e-82
Identities = 178/456 (39%), Positives = 266/456 (58%), Gaps = 10/456 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL+VIG+GPGGYVAAIKAA+LGMK +E + +GGTCLN GC+P+KA+LH + LY
Sbjct: 6 DLLVIGAGPGGYVAAIKAAKLGMKTAVIE-NREVGGTCLNRGCVPAKAMLHAAKLYQEVL 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+Q GI EV+FD+ K+M YK + L G+ L + NKV ++G+GT++ +V
Sbjct: 65 SG-EQFGILVEEVSFDYGKVMSYKNETSESLRLGVEQLLKGNKVERLQGIGTLLKDGRVR 123
Query: 153 VHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
+ ++G E + KNIL+A+GS+ + P G+ I+TS L+ VP+ +L+IG G
Sbjct: 124 IKTKEGEEILQAKNILLATGSKPVLPPIEGIHLPG--IMTSDEMFQLDHVPESLLIIGGG 181
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
VIG+E +VY G+ VT +E + G+D E+++ ++ +L K+G+ V ++
Sbjct: 182 VIGVEFATVYSSFGSKVTLLEAEERLLP-GLDKEISQNIKLLLKKRGVDIHTRAFVQKIE 240
Query: 271 K-EGSTIKVDVEAAKGGNK-EVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
K + I +E K K EV +L + GR P T GL L++ + DRGRI VN
Sbjct: 241 KVDCEFICTFLEKGKDQEKAEVRKIPYLLSATGRIPNTHGL-LEETTLLEMDRGRILVNE 299
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGW 388
F+T++P ++AIGDVI G LAH A +GI VE + G + +PS +YT PE+
Sbjct: 300 NFETSMPNVFAIGDVIGGSQLAHVASSQGICAVERMNGKEPSIDLSVVPSCVYTDPEIAC 359
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VG TE++ K++G GKF ANS++ E GFVKV+ DK T+V+LG ++
Sbjct: 360 VGITEQEAKEKGIETVTGKFLTHANSKSLITKEERGFVKVVIDKETNVLLGAQMMCARAT 419
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
++I E A A + + AHPT E++ EA
Sbjct: 420 DMIGEMGTAISNKLTAMQLLKAMRAHPTYNESIAEA 455
>UniRef50_A6TMP2 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Alkaliphilus metalliredigens QYMF|Rep: Dihydrolipoyl
dehydrogenase - Alkaliphilus metalliredigens QYMF
Length = 457
Score = 308 bits (755), Expect = 3e-82
Identities = 180/470 (38%), Positives = 275/470 (58%), Gaps = 22/470 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYH-MA 91
D++V+G GPGGYVAAIKAA LG KV VE GG CLN GCIP+KALL N+ +Y +
Sbjct: 4 DVLVLGGGPGGYVAAIKAAHLGGKVALVENG-YFGGVCLNWGCIPTKALLKNARVYQDVL 62
Query: 92 KHDFKQ-RGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
DF GI+ +++ ++ M++ K V+ L GG+ L +KNKV++ G GT++ N
Sbjct: 63 MGDFYGIEGIDKSQLSINWPAMLKRKDRIVRQLVGGVKGLLKKNKVDVFDGFGTLIDANH 122
Query: 151 VEVHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEK--QIITSTGALSLESVPKKMLV 206
+EV G++ + K ++IA+G+ + PG+ K I+TS LS+E++PK +++
Sbjct: 123 IEVKGQQ----LEGKKLIIATGTSPMIPDIPGLEASMKAGNILTSKELLSIEALPKSVVI 178
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
+G GVI +E ++ L +VT I+ I G++ E+A TL K L K+ +K + V
Sbjct: 179 LGGGVIAIEFATLLNALDVEVTVIQRSDRILK-GVEEEMALTLSKDLIKRKVKIVTNSSV 237
Query: 267 LGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPV 326
K EG+ + + G +E+ + D +L+S+G P KGL + + + +D +G I
Sbjct: 238 --EKIEGTRVFTKIN----GEEEIFEGDKILLSLGTSPNVKGL--EALSLDMDKKGII-T 288
Query: 327 NNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEV 386
N+K +T++ G+YAIGDV LAH A EGIV E G NY+ +PS IY+ PE+
Sbjct: 289 NDKMETSITGVYAIGDVNGKYQLAHVASAEGIVAAENAMGGNEELNYNIVPSCIYSFPEI 348
Query: 387 GWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPG 446
VG TEE+ +++ V KFP AN +A GE GFVK+++DK ILGTHI+
Sbjct: 349 ASVGLTEEEARQKDYDVVVSKFPLAANGKAMAEGENIGFVKIIADKKYGEILGTHIMAVH 408
Query: 447 GGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 496
++I+EA+++ + A DVA+ H HPT +E + EA +PI+F
Sbjct: 409 ATDMISEAIVSMQLEGTAYDVAKAIHPHPTMSEIVMEA-AHGIMDQPIHF 457
>UniRef50_Q9KES0 Cluster: Dihydrolipoyl dehydrogenase; n=1; Bacillus
halodurans|Rep: Dihydrolipoyl dehydrogenase - Bacillus
halodurans
Length = 462
Score = 305 bits (748), Expect = 2e-81
Identities = 188/471 (39%), Positives = 269/471 (57%), Gaps = 23/471 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVE-KDPTLGGTCLNVGCIPSKALLHNSHLYHMA 91
D+VVIG GPGGYVAAIKAA+LG KV VE KD LGGTCLN GCIPSK LLH +
Sbjct: 5 DIVVIGGGPGGYVAAIKAAKLGKKVALVEAKD--LGGTCLNRGCIPSKTLLHQGEIIEKI 62
Query: 92 KHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
K K+ GIETG VT KM+ K ++ L GI L ++ K+++ G G I V
Sbjct: 63 KQA-KEWGIETGAVTLSLPKMLARKNEIIQKLRAGIHFLLKQGKIDVYFGYGEIERDRSV 121
Query: 152 EVHGEKGVE--TVNTKNILIASGSEVT--PFPGVTFDEKQIITSTGALSLESVPKKMLVI 207
++ ++ E +V T+N+++A+G+E T P PG+ E + TS L+S+P+ +++I
Sbjct: 122 KIKMKETAEIVSVRTENMIVATGTEPTIPPVPGLA--EAVVDTSDTIFELDSIPQSIVII 179
Query: 208 GAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVL 267
G GVIG+E+ ++ L DVT +E I D E AK L K L+ +G+ TKV
Sbjct: 180 GGGVIGVEIACIFSSLQVDVTIVEMGKRILPQE-DEEAAKVLAKALAAKGVHLLTNTKVT 238
Query: 268 GVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRP---YTKGLGLDKVGIALDDRGRI 324
V +G KV++E + G +++ L+ + +L+++GR P K LGL G L
Sbjct: 239 AVL-QGDKQKVEIETSTG-DRDWLEGERILLAVGRTPNLSVVKELGLGMAGPFLK----- 291
Query: 325 PVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSP 384
V+++ +T+ P IYAIGDVI G LAH A EG+V G N IP IYT P
Sbjct: 292 -VDDQMRTSDPSIYAIGDVIGGWQLAHVASAEGLVAAANASGKVEIINRQVIPRCIYTQP 350
Query: 385 EVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 444
E+ VG TE++ K++G +YKV K AN +A GET GFVK+++D ILG ++G
Sbjct: 351 EIASVGLTEQEAKEKGYSYKVVKVDLRANGKAMALGETTGFVKMIADPNYGEILGVTMVG 410
Query: 445 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
P E+I E +++ + H HPT +EAL EA A++ G+ ++
Sbjct: 411 PHVTEMIGEPAAFIHLEGTVDELKAMIHPHPTVSEALYEA-AASWLGQGVH 460
>UniRef50_Q24PW4 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Desulfitobacterium hafniense Y51|Rep: Dihydrolipoyl
dehydrogenase - Desulfitobacterium hafniense (strain
Y51)
Length = 461
Score = 304 bits (746), Expect = 4e-81
Identities = 181/463 (39%), Positives = 269/463 (58%), Gaps = 12/463 (2%)
Query: 34 LVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAKH 93
+ V+GSGP GYVAAI+A+QLG +VV +E++ LGG CLN GCIP+KALL + + MAK
Sbjct: 8 IAVLGSGPAGYVAAIRASQLGAEVVVIEEED-LGGVCLNRGCIPTKALLKTAEIAVMAKR 66
Query: 94 DFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVEV 153
K+ GIE+ ++ ++ K VK L G+ L + + ++KG GT+++ K+ V
Sbjct: 67 S-KEFGIESQLEAKNWGVAVDRKNRIVKNLNSGLDNLLRARGITVLKGKGTVLSERKILV 125
Query: 154 HGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVIG 213
+ V VN + +++ +G+ P D +ITS AL+L+++P+ +++IGAGVIG
Sbjct: 126 QTTEEVIEVNCEKMILTTGAVPLILPIKGIDSAGVITSDEALNLKALPESIVIIGAGVIG 185
Query: 214 LELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKEG 273
LE ++ G VT IE I D E+A LQKI+ +QG+ FKL V + K
Sbjct: 186 LEFAAMLGHAGVKVTIIELQDRILP-NEDREIAAELQKIMKRQGIIFKLSASVTEIHKIE 244
Query: 274 STIKVDVEAAKGGNKEVLD-CDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQT 332
+ V G KE C+ VL++ GR+ T +K+ + ++ +G + V+ +T
Sbjct: 245 DGLIVTYSM---GEKEFRHPCEKVLVAAGRK--TNSDIFEKLPLTIE-KGAVVVDEFMET 298
Query: 333 TVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGKT 392
V G+YA GD++ G LAH A EG V E G+ NY A+P+ IYT+PE+ VG T
Sbjct: 299 NVKGVYAAGDLVGGKQLAHLAFMEGKVAAENALGITSKVNYSAVPTCIYTNPEMASVGMT 358
Query: 393 EEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELIN 452
EE K+ G + KVG+F F N RA T GE EGFVKV++D+ + I+G I+G E+I+
Sbjct: 359 EEQAKRAGLSVKVGRFDFRNNGRALTLGEREGFVKVIADQ-DNTIIGGQILGVDASEMIS 417
Query: 453 EAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
E LA A A+D+A + H HP +EA+ EA GKPI+
Sbjct: 418 ELTLAITLKAKADDIADMIHPHPALSEAIWEA-CGEILGKPIH 459
>UniRef50_Q2JND9 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Cyanobacteria|Rep: Dihydrolipoyl dehydrogenase -
Synechococcus sp. (strain JA-2-3B'a(2-13))
(Cyanobacteria bacteriumYellowstone B-Prime)
Length = 460
Score = 303 bits (744), Expect = 7e-81
Identities = 170/455 (37%), Positives = 264/455 (58%), Gaps = 10/455 (2%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
D DL++IG+G GG+ AA+ A + G+K VE +GGTC+N GCIPSKALL S
Sbjct: 4 DFDLIIIGAGVGGHGAALHAVESGLKTAIVE-GAEMGGTCINRGCIPSKALLAASGRLRE 62
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
+H GI+ G + + + + + A V+ + + +K V +++G G +VAP +
Sbjct: 63 LQHS-SGLGIQVGSLQVNREAIANHAAQVVEKIRADMTRSLEKLGVTILRGRGKLVAPQQ 121
Query: 151 VEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
VEV EKG T +++++A+GS PG+ D + + TS A+ LE +P+++ +IG+G
Sbjct: 122 VEVQEEKGSHTYTAQDVILATGSRPFVPPGIEVDGRTVFTSDEAVRLEWIPERLAIIGSG 181
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSK-QGMKFKLGTKVLGV 269
IG E +Y LG+ V IE L ++ D ++A+ Q++L K + ++ +G V
Sbjct: 182 YIGQEFADIYTALGSQVILIEALETLMPA-FDPDIARLAQRVLIKPRSIQTFVGVLARQV 240
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
G + + + N E L D L++ GR P ++GLGL ++GI RG IPV+++
Sbjct: 241 IP-GQPVTIHLS-----NGETLQVDGCLVAAGRIPVSEGLGLAELGIDTGKRGFIPVDSR 294
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWV 389
T +P ++AIGDV MLAH A +G V VE I G + +Y +IP+ ++T PE+G+V
Sbjct: 295 MATDLPHLWAIGDVTGKMMLAHAAAAQGRVAVENICGRTAYMDYLSIPAAVFTHPEMGFV 354
Query: 390 GKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGE 449
G TE K+EG + + F NS+A +GETEG VK++ DK+T ++LG+HI GP +
Sbjct: 355 GLTEPQAKEEGYSVGTVRTYFGGNSKAIASGETEGMVKLVFDKSTGLLLGSHIFGPHAAD 414
Query: 450 LINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
LI+EA A A ++A + H HPT AE L EA
Sbjct: 415 LIHEAAQAIARRATVRELAGLVHVHPTLAETLEEA 449
>UniRef50_Q8KCW2 Cluster: Dihydrolipoyl dehydrogenase; n=11;
Chlorobiaceae|Rep: Dihydrolipoyl dehydrogenase -
Chlorobium tepidum
Length = 469
Score = 303 bits (744), Expect = 7e-81
Identities = 175/454 (38%), Positives = 252/454 (55%), Gaps = 7/454 (1%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+ VIGSGPGGY AAI AA+ G+K VEK LGG C+N GCIP+KALL ++ ++ +AK
Sbjct: 12 DVAVIGSGPGGYEAAIHAARYGLKTCIVEK-AVLGGVCVNWGCIPTKALLRSAEVFDLAK 70
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ + G+ G V+FD + ++ N + G+A L +K V ++ G + V
Sbjct: 71 NP-ETFGVNVGNVSFDLAQAVKRSRNVALKSSKGVAYLLKKAAVEVLAGEAVLTGGAGVM 129
Query: 153 VHGEKG-VETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGV 211
V G V + KNI++A+GS PG+ D K+IITS AL L+ VPK M+V+G G
Sbjct: 130 VTMPDGSVRMLGAKNIIVATGSTPRVIPGLEPDGKKIITSREALILKEVPKSMIVVGGGA 189
Query: 212 IGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKK 271
IG+E+ Y + G+ VT +E + + + EV++ L++ K G+ G K+ V
Sbjct: 190 IGVEMAWFYAKAGSKVTIVELMPRMLPAE-EAEVSEALKRSFEKAGITVHCGAKLDNVAV 248
Query: 272 EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQ 331
S + ++ +G + L+ +L+++G GLGLD VG+ + RG I + + +
Sbjct: 249 SESGVSAEL-VVEGSAPQTLNASCLLVAVGVTGAIDGLGLDAVGVETE-RGFIRTDGQCR 306
Query: 332 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGM-PVHFNYDAIPSVIYTSPEVGWVG 390
T+ PGIYAIGDV G +LAHKA E + VE I G P + IP +Y P V VG
Sbjct: 307 TSAPGIYAIGDVRGGMLLAHKASAEAAIAVEAIAGKSPEPLSEPLIPRCVYAQPSVASVG 366
Query: 391 KTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGEL 450
TEE G VG+ F A+ +A G+ EGFVK++ D T +LG H+IG EL
Sbjct: 367 LTEEAAVNAGYQVAVGRSQFAASGKANAYGQLEGFVKLVFDAATGKMLGGHLIGHDAVEL 426
Query: 451 INEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
I E LA YG A + HAHPT +E +REA
Sbjct: 427 IGELGLACRYGVTAGGLVNTVHAHPTLSETVREA 460
>UniRef50_Q49111 Cluster: Dihydrolipoamide dehydrogenase; n=7;
root|Rep: Dihydrolipoamide dehydrogenase - Mycoplasma
capricolum
Length = 629
Score = 300 bits (736), Expect = 6e-80
Identities = 183/479 (38%), Positives = 262/479 (54%), Gaps = 29/479 (6%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+ V+G+G GGYV AIK+AQLG+K + +EK+ GG CLNVGCIP+K LL SH+YH
Sbjct: 165 DVCVVGAGIGGYVTAIKSAQLGLKTLIIEKE-YYGGVCLNVGCIPTKTLLKTSHVYHDIV 223
Query: 93 HDFKQRGI---ETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPN 149
H K+ GI T V D+ + +E K VK LTGG+ L KNKV +KG + N
Sbjct: 224 HKAKELGIVLQNTENVVIDWAQALERKNGVVKKLTGGVKYLLDKNKVTQIKGEAIALDKN 283
Query: 150 KVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQ----IITSTGALSLESVPKKML 205
+ V+ + N++IASGS P FD+ + II STG LS+ +P+ ++
Sbjct: 284 TISVNNKN----YRVNNLVIASGSTPNHLPLPGFDQGRKDGIIIDSTGILSVPKIPETLV 339
Query: 206 VIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTK 265
VIG GVIG+E ++ LG VT ++ L +I + +D ++ + K L + +
Sbjct: 340 VIGGGVIGIEFSCLFASLGTKVTVLQGLPTILEM-LDKDIIDAMTKELKNRYNIQVITNA 398
Query: 266 VLGVKKEGSTI-KVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRI 324
+ K+GS + ++D G +++ + VL S+GR+ T G + +G+ L R +
Sbjct: 399 SVKEFKDGSVVYQID------GQDQMIKGEYVLESVGRK--TSLTGFENIGLELTPRKGV 450
Query: 325 PVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI--KGMPVH-----FNYDAIP 377
VN +T + G+YAIGDV+ MLA A IV I K H NYD +P
Sbjct: 451 VVNEYQETNLDGVYAIGDVVGKSMLAQTAVKGAIVAANRIAKKANKAHAEDIVMNYDKVP 510
Query: 378 SVIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVI 437
S IYT PEV +GKTE+ LK+E YK KFPF A +A + +T GFVK++ + I
Sbjct: 511 SCIYTHPEVSMIGKTEQQLKQENIEYKAFKFPFSAIGKALADDDTSGFVKIIVEPKYKTI 570
Query: 438 LGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 496
LG HIIG E+I+E E ++A H HPT +EA+ EA A +GK I+F
Sbjct: 571 LGAHIIGNRATEMISEITAVIECEGTITEIANTIHPHPTMSEAIGEAAEALETGKAIHF 629
>UniRef50_P50970 Cluster: Dihydrolipoyl dehydrogenase; n=25;
Proteobacteria|Rep: Dihydrolipoyl dehydrogenase -
Zymomonas mobilis
Length = 466
Score = 300 bits (736), Expect = 6e-80
Identities = 173/468 (36%), Positives = 261/468 (55%), Gaps = 11/468 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL+V+G GPGGYVAAI+AAQL +KV VE+ LGG CLN GCIP+K+LL ++ +YH +
Sbjct: 6 DLIVLGGGPGGYVAAIRAAQLNLKVALVER-VHLGGICLNWGCIPTKSLLRSAEVYHEMQ 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ + G+ + + FD K++ L G+ L +KNKV ++ GVG + ++
Sbjct: 65 NA-EAYGLTSFKPDFDLDKIIARSREVATRLASGVKTLLRKNKVEVISGVGQLTGNQQML 123
Query: 153 VHGEKGVETV-NTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGV 211
V +G E + K+I+IA+G+ P V D K I T AL ++PKK+LVIG+G
Sbjct: 124 VETTEGEEKILEAKDIIIATGARARQLPNVHSDGKHIWTYHHALKPPAMPKKLLVIGSGA 183
Query: 212 IGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKK 271
IG+E S Y GA+V+ +E I + D EV+ + K K+G++ + + +
Sbjct: 184 IGIEFASFYADFGAEVSIVEHAPQILPME-DAEVSAYVAKAFKKRGIRILTQSALQNLTP 242
Query: 272 EGSTIKVDVEAAKGG-NKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
+ + ++ A G KE +V I + + +GLDK+GI LD RG I V+
Sbjct: 243 DDEGVTAEIAGADGKVTKERFSHAIVAIGVVAN--VENIGLDKLGIKLD-RGFIAVDGFG 299
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMP-VH-FNYDAIPSVIYTSPEVGW 388
+T V ++AIGDV P LAHKA +G++ E I G VH N IP Y P+V
Sbjct: 300 RTNVDHVWAIGDVAGAPCLAHKASHQGVIAAEAIAGCDHVHPLNTQNIPGCTYARPQVAS 359
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VG TEE +++G K+G FPF+AN +A G T+GFVK + D + +LG H++G
Sbjct: 360 VGLTEEKARQQGYNVKIGNFPFIANGKAIAQGATDGFVKTVFDADSGALLGAHMVGAEVT 419
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 496
E+I +A+ ++ HPT +EA+ E+ LAAY G+ ++F
Sbjct: 420 EMIQGYTVARTLETTEAEIMETIFPHPTLSEAMHESVLAAY-GRALHF 466
>UniRef50_Q9I1L9 Cluster: Dihydrolipoyl dehydrogenase; n=54;
Proteobacteria|Rep: Dihydrolipoyl dehydrogenase -
Pseudomonas aeruginosa
Length = 464
Score = 300 bits (736), Expect = 6e-80
Identities = 175/458 (38%), Positives = 267/458 (58%), Gaps = 12/458 (2%)
Query: 34 LVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAKH 93
L+++G GPGGYVAAI+A QLG+ V VE LGGTCLNVGCIPSKAL+H + Y A+H
Sbjct: 9 LLIVGGGPGGYVAAIRAGQLGIPTVLVE-GAALGGTCLNVGCIPSKALIHAAEEYLKARH 67
Query: 94 DFKQR--GIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
+ GI+ + D + +E+K V LT G+A L +K+ V++V+G I+ V
Sbjct: 68 YASRSALGIQVQAPSIDIARTVEWKDAIVDRLTSGVAALLKKHGVDVVQGWARILDGKSV 127
Query: 152 EVH-GEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
V G + + +++L+A+GS+ P + K +I+ST AL+ S+PK+++V+G G
Sbjct: 128 AVELAGGGSQRIECEHLLLAAGSQSVELPILPLGGK-VISSTEALAPGSLPKRLVVVGGG 186
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
IGLELG+ Y++LG +V +E I G D E+ K + + L + G++ LG +LG
Sbjct: 187 YIGLELGTAYRKLGVEVAVVEAQPRILP-GYDEELTKPVAQALRRLGVELYLGHSLLGPS 245
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
+ G V V G +E+ D VL+++GR+P ++G L+ +G+ ++ R + V+++
Sbjct: 246 ENG----VRVRDGAGEEREIA-ADQVLVAVGRKPRSEGWNLESLGLDMNGRA-VKVDDQC 299
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVG 390
+T++ ++AIGD+ PMLAH+A +G + E I G F AIP+V +T PEV G
Sbjct: 300 RTSMRNVWAIGDLAGEPMLAHRAMAQGEMVAELIAGKRRQFAPVAIPAVCFTDPEVVVAG 359
Query: 391 KTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGEL 450
+ E K G V FPF AN RA T EGFV+V++ + +++G +G EL
Sbjct: 360 LSPEQAKDAGLDCLVASFPFAANGRAMTLEANEGFVRVVARRDNHLVVGWQAVGKAVSEL 419
Query: 451 INEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAA 488
+ E GA ED+A HAHPT EA++EA L A
Sbjct: 420 STAFAQSLEMGARLEDIAGTIHAHPTLGEAVQEAALRA 457
>UniRef50_O34324 Cluster: Dihydrolipoyl dehydrogenase; n=13;
Bacillus|Rep: Dihydrolipoyl dehydrogenase - Bacillus
subtilis
Length = 458
Score = 296 bits (726), Expect = 1e-78
Identities = 170/457 (37%), Positives = 244/457 (53%), Gaps = 12/457 (2%)
Query: 34 LVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAKH 93
L +IG GP GY AA+ AAQ G V+ ++K LGGTCLN GCIP+K+LL ++++ KH
Sbjct: 3 LAIIGGGPAGYAAAVSAAQQGRNVLLIDKGK-LGGTCLNEGCIPTKSLLESANVLDKIKH 61
Query: 94 DFKQRGIE--TGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
GIE G ++ D+ KM K V L G+ L +KN++ +VKG + ++ K+
Sbjct: 62 A-DSFGIELPAGAISVDWSKMQSRKQQVVSQLVQGVQYLMKKNQIQVVKGTASFLSERKL 120
Query: 152 EVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGV 211
+ GE G E +LIASGSE P FD + I+ S ALSL +P ++++G GV
Sbjct: 121 LIEGENGKEIREADQVLIASGSEPIELPFAPFDGEWILDSKDALSLSEIPSSLVIVGGGV 180
Query: 212 IGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKK 271
IG E ++ RLG+ VT IE + D ++A+ Q+ L + G++ +++ V +
Sbjct: 181 IGCEYAGLFARLGSQVTIIETADRLIPAE-DEDIARLFQEKLEEDGVEVHTSSRLGRVDQ 239
Query: 272 EGSTIKVDVEAAKGGNKEV-LDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
T K G +E D VL++IGR+P GL L++ G+ +G IPVN
Sbjct: 240 TAKTA-----IWKSGQREFKTKADYVLVAIGRKPRLDGLQLEQAGVDFSPKG-IPVNGHM 293
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVG 390
QT VP IYA GD I G LAH A EGI+ G V N +P IYTSPE+ +G
Sbjct: 294 QTNVPHIYACGDAIGGIQLAHAAFHEGIIAASHASGRDVKINEKHVPRCIYTSPEIACIG 353
Query: 391 KTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGEL 450
TE + K+G+F F AN +A + EG VK++++ I+G +IGP EL
Sbjct: 354 MTERQARSIYGDVKIGEFSFSANGKALIKQQAEGKVKIMAEPEFGEIVGVSMIGPDVTEL 413
Query: 451 INEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 487
I +A A+ AHPT +E L EA L+
Sbjct: 414 IGQAAAIMNGEMTADMAEHFIAAHPTLSETLHEALLS 450
>UniRef50_Q9WYL2 Cluster: Dihydrolipoamide dehydrogenase; n=6;
Bacteria|Rep: Dihydrolipoamide dehydrogenase -
Thermotoga maritima
Length = 449
Score = 295 bits (725), Expect = 1e-78
Identities = 177/463 (38%), Positives = 258/463 (55%), Gaps = 17/463 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D V+IG GPGGYV AIK AQLG KV VEKD LGGTC N GCIP+KA+L SHL K
Sbjct: 3 DAVIIGGGPGGYVCAIKLAQLGKKVALVEKD-ALGGTCTNRGCIPTKAMLTVSHLMDEMK 61
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ G++ V +D +M++ +V GI L +KN V + KG + N V
Sbjct: 62 EKASKYGLKVSGVEYDVAAIMKHVQKSVMMSRKGIEYLLKKNGVEVFKGTAVVENKNTVV 121
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVI 212
V E G E + KN+++A GS + F FD + TS +L+ PK ++++G GVI
Sbjct: 122 VQ-ETG-EKLEAKNLVLAHGSVPSVFS--PFDIDGVWTSDDVFNLKEFPKSLVIVGGGVI 177
Query: 213 GLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKE 272
G+E + + G DVT +E I D +VA+ ++K L ++G+K TK+ + K
Sbjct: 178 GVEFATFFGSFGVDVTIVEIAEHILPYE-DSDVAEEVKKALKRKGVKILEKTKISSLSKV 236
Query: 273 GSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQT 332
+V +E N E L + VL++ GR+P + +G+ ++ +G + +++ +T
Sbjct: 237 DDGFEVALE-----NGETLKAEKVLLAAGRKPNIPE-DVKALGVKIE-KG-VVTDSRMRT 288
Query: 333 TVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGKT 392
V +YAIGD+ G MLAH A EGIV + I G +Y A+PS+I++SPEV VG
Sbjct: 289 NVENVYAIGDIRSGIMLAHVAMYEGIVAAKNIAGEEEEMDYSAVPSIIFSSPEVASVGVR 348
Query: 393 EEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELIN 452
E+D+ E + KFP AN RA+T E GF KV++DK +LG I+ P ++I
Sbjct: 349 EKDVNPE--EVVISKFPVSANGRARTMLENIGFAKVIADKKDGTVLGMSIVSPSATDMIM 406
Query: 453 EAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
E V+A ++ AED+ + H HPT E + A L SGKPI+
Sbjct: 407 EGVIAVKFRMKAEDLEKAIHPHPTLTETILGA-LEGVSGKPIH 448
>UniRef50_Q18CC1 Cluster: E3 component of acetoin dehydrogenase
enzyme system; n=2; Clostridium difficile|Rep: E3
component of acetoin dehydrogenase enzyme system -
Clostridium difficile (strain 630)
Length = 576
Score = 295 bits (724), Expect = 2e-78
Identities = 179/464 (38%), Positives = 268/464 (57%), Gaps = 17/464 (3%)
Query: 30 HDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYH 89
HD D+VVIG GPGGY++A+KAA LG +V VE++ LGGTCLN GCIP+K + + +
Sbjct: 122 HDYDVVVIGGGPGGYLSALKAALLGGRVALVEEN-ILGGTCLNRGCIPTKTYIKTAEILE 180
Query: 90 MAKHDFKQRGIE-TGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAP 148
+RG++ T + D KK ++YK VK LT G+ L + V++ ++
Sbjct: 181 EIDQ-LSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGVGGLLKSRDVDVFNLKASVKEE 239
Query: 149 NKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
+KV + K ++T+NI+IA+GS+V P + IITST AL LE+VP+++++IG
Sbjct: 240 HKVILSDGK---VLDTENIIIATGSKVRILPIKGIESNLIITSTEALDLETVPEELVIIG 296
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
GVIG E ++ G+ VT +E + +D E++++L+ LSK+G+ KV
Sbjct: 297 GGVIGCEFAEIFNSRGSKVTIVEMEDRVIP-RMDKELSESLKYSLSKKGINVLTKKKVSE 355
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
K+EG+ I V +E +E + D+ L +IGR G+ + + I +D +G I VN+
Sbjct: 356 FKEEGNNILVCIEG-----EEPIKADLCLYAIGREANLSGI--EDLDIKID-KGSIVVNS 407
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGW 388
K +T++P IYA+GDV G MLAH A G V G+ + A+PS +YT PEV
Sbjct: 408 KMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEVDLGALPSCVYTIPEVAS 467
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VG TEED +K+ KVGKF F N RA +G+ +G+VKV++D ILG H+ G G
Sbjct: 468 VGITEEDARKKYNV-KVGKFNFAGNGRALASGQEQGYVKVVADAKYGEILGIHMFGCGVA 526
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGK 492
ELIN A + ++ + + HP +EAL EA LA +G+
Sbjct: 527 ELINHAASFKALEIPTDEASELIFGHPCTSEALMEA-LADVNGE 569
>UniRef50_A1SYC1 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Proteobacteria|Rep: Dihydrolipoyl dehydrogenase -
Psychromonas ingrahamii (strain 37)
Length = 463
Score = 294 bits (722), Expect = 3e-78
Identities = 175/465 (37%), Positives = 258/465 (55%), Gaps = 13/465 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+++IG GPGGYV+AIKAAQ +KV VEKD +GG CLN GCIP+KALL + +
Sbjct: 9 DVIIIGGGPGGYVSAIKAAQNNLKVALVEKDK-MGGICLNWGCIPTKALLKSGEFINKL- 66
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
H G+ + +FD K ++ + K L G+ L +KN + + I++ +KV
Sbjct: 67 HKANDFGVVVDKFSFDLKSIVNRSRDISKNLNKGVDALMKKNGITVFNDTAKIISNHKVA 126
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVI 212
+ + T+NTKNI+IA+GS+ PG+ D + A++ + VP+ +L+IGAG I
Sbjct: 127 LSNQ----TLNTKNIVIATGSKSKIIPGLEPDGNVVWNYRNAMTPKKVPENLLIIGAGAI 182
Query: 213 GLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKE 272
G+E Y LG++VT +E +I D +V+ +K K G+ TKV ++K
Sbjct: 183 GVEFACFYNSLGSNVTIVENQENILSTE-DDDVSALAKKHFIKLGISILNSTKVNFIEKS 241
Query: 273 GSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQT 332
+I ++ + KE D V+++IG +GL+ +GI + G I N QT
Sbjct: 242 KDSITFELTSENF--KETKVFDNVIMAIGVSGSFDNIGLETLGIKTN-HGFIETNEFMQT 298
Query: 333 TVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI--KGMPVHFNYDAIPSVIYTSPEVGWVG 390
VP IYAIGDV P LAHKA EGI+C+E I K N ++IPS IY+ P++ +G
Sbjct: 299 NVPNIYAIGDVAGAPCLAHKASHEGIICIEKILNKNNIKTLNNNSIPSCIYSYPQIASLG 358
Query: 391 KTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGEL 450
TE+ + G Y VG+FPF AN +A +GET+GF+K L T +LG H+IG E+
Sbjct: 359 LTEKAVIASGETYTVGRFPFNANGKAIASGETDGFIKTLFSANTGELLGVHMIGAEVTEM 418
Query: 451 INEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
I + +E ++ V HPT +EA+ EA L A S K I+
Sbjct: 419 IQGYAIGKELETTQVELEHVIFPHPTMSEAMHEAVLDA-SDKAIH 462
>UniRef50_Q1Q2Y9 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Dihydrolipoyl
dehydrogenase - Candidatus Kuenenia stuttgartiensis
Length = 472
Score = 293 bits (720), Expect = 5e-78
Identities = 163/458 (35%), Positives = 265/458 (57%), Gaps = 12/458 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL +IG GP GYVAAIKAAQ G+K +EK+ +GGTCL+ GCIP+K LL+++ LY
Sbjct: 7 DLAIIGGGPAGYVAAIKAAQSGLKTALIEKEK-VGGTCLHKGCIPTKTLLYSAELYRKFA 65
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ + GI TG + D+ + K VK L G+ L +KN V++ G I++ +V
Sbjct: 66 NA-GEYGITTGSLNVDYPLIHRRKEYVVKRLFQGVQSLLKKNGVDVFSAEGRIISNQEVS 124
Query: 153 VHGEKGVET--VNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
+ + G+ET + KNI++A+GS + +D+K ++TS L E +PK ++++G G
Sbjct: 125 IVSD-GIETNRIKVKNIILATGSAPFIPKNIPYDKKYVLTSDDILLREEIPKSIIIVGGG 183
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
+G+E ++ G +VT +E L I D E+ T++ +L ++G+ T + V+
Sbjct: 184 AVGIEFACLFNAFGTEVTVLELLEDI-LPSEDKEINGTVKNLLIRRGVNVLTQTSLEKVE 242
Query: 271 KEGSTIKVDVEAAK--GGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
E +K++++ GN+E L D++L++ GR P +G++++ + D + + N
Sbjct: 243 IENG-VKLEIKGVNDISGNREFLHADLLLLAAGRVPLLDNIGIEEMSLNFDGQ-YLRTNE 300
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH-FNYDAIPSVIYTSPEVG 387
+T+ G+YAIGD+ P+LAHKA +EGI+ V + G +H N IP V+Y+ P+V
Sbjct: 301 GMETSQRGVYAIGDITGAPLLAHKAINEGILSVTHLTGKDMHIINRKNIPRVVYSFPQVA 360
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGET-EGFVKVLSDKTTDVILGTHIIGPG 446
+G T+++ ++ G K+GKFPF ANS A GE+ +GFVK++S++ ILG H IG
Sbjct: 361 SIGLTQKEAEEMGYKVKIGKFPFAANSMAIIEGESLDGFVKIVSEEKYGEILGVHAIGHH 420
Query: 447 GGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
GE + L ++V+ HPT +EAL EA
Sbjct: 421 VGEWMWGLSLNSILEGTVQEVSNAIFPHPTLSEALFEA 458
>UniRef50_Q9S2Q6 Cluster: Dihydrolipoyl dehydrogenase; n=32;
Bacteria|Rep: Dihydrolipoyl dehydrogenase - Streptomyces
coelicolor
Length = 486
Score = 293 bits (719), Expect = 7e-78
Identities = 180/466 (38%), Positives = 274/466 (58%), Gaps = 19/466 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DLV++G G GGY AA++ AQLG+ V +EK+ LGGTCL+ GCIP+KALLH + ++
Sbjct: 34 DLVILGGGSGGYAAALRGAQLGLDVALIEKNK-LGGTCLHNGCIPTKALLHAGEVADQSR 92
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+Q G++T D + +YK + GL G+ L K+ ++G G + +P V+
Sbjct: 93 ES-EQFGVKTSFEGVDMAGVHKYKDEVIAGLYKGLQGLVASRKITYIEGEGRLSSPTSVD 151
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVI 212
V+G++ V +++L+A+GS PG+ D +II+S AL+L+ VPK +V+G GVI
Sbjct: 152 VNGQR----VQGRHVLLATGSVPKTLPGLEIDGNRIISSDHALTLDRVPKSAIVLGGGVI 207
Query: 213 GLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKE 272
G+E S ++ G++VT IE L + V D +K L++ K+G+KF LGT K E
Sbjct: 208 GVEFASAWKSFGSEVTVIEGLKHLVPVE-DENSSKLLERAFRKRGIKFNLGT--FFQKAE 264
Query: 273 GSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQT 332
+ V V A G KE + +V+L++IGR P ++GLG ++ G+A DRG + V+ +T
Sbjct: 265 YTQDGVKVTLADG--KE-FEAEVLLVAIGRGPVSQGLGYEENGVA-TDRGFVLVDEYMRT 320
Query: 333 TVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGM-PVHFNYDAIPSVIYTSPEVGWVGK 391
VP I A+GD++ LAH EGI+ E + G+ V +YD +P V Y PEV VG
Sbjct: 321 NVPTISAVGDLVPTLQLAHVGFAEGILVAERLAGLKTVPVDYDGVPRVTYCHPEVASVGL 380
Query: 392 TEEDLKKEGRAYKVG--KFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGE 449
TE K+ A KV KFP N +++ +T G +K++ K ++G H++G GE
Sbjct: 381 TEARAKEVYGADKVVSIKFPLGGNGKSRIL-KTAGEIKLVQVK-DGAVVGVHMVGDRMGE 438
Query: 450 LINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
+ EA L + A +VA++ HAHPT EAL EA+L A +GKP++
Sbjct: 439 QVGEAQLIYNWEALPAEVAQLIHAHPTQNEALGEAHL-ALAGKPLH 483
>UniRef50_Q8A2W9 Cluster: Dihydrolipoyl dehydrogenase; n=7;
Bacteria|Rep: Dihydrolipoyl dehydrogenase - Bacteroides
thetaiotaomicron
Length = 447
Score = 292 bits (717), Expect = 1e-77
Identities = 170/454 (37%), Positives = 245/454 (53%), Gaps = 15/454 (3%)
Query: 34 LVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAKH 93
+++IG GP GY AA A + G+ V+ +EK+ LGG CLN GCIP+K LL+++ Y A+H
Sbjct: 5 VIIIGGGPAGYTAAEAAGKAGLSVLLIEKN-NLGGVCLNEGCIPTKTLLYSAKTYDSARH 63
Query: 94 DFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVEV 153
K + EV+FD K++ K+ V+ L G+ N V +V G I+ N V
Sbjct: 64 SSKY-AVNVSEVSFDLPKIIARKSKVVRKLVLGVKAKLTSNNVAMVTGEAQIIDKNTVRC 122
Query: 154 HGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGV 211
G ET N +N+++ +GSE + P GV + T AL + +P + ++G GV
Sbjct: 123 ----GEETYNAENLILCTGSETFIPPITGV--ETVNYWTHRDALDSKELPASLAIVGGGV 176
Query: 212 IGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKK 271
IG+E S + LG VT IE + I G G+D E++ L+ +K+G+KF L TKV+ + +
Sbjct: 177 IGMEFASFFNSLGVQVTVIEMMDEILG-GMDKELSALLRAEYAKRGIKFLLSTKVVALSQ 235
Query: 272 EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQ 331
V E A+G + + +L+S+GRRP TKG GL+ + + RG I VN K Q
Sbjct: 236 TEEGAVVSYENAEGKGSVI--AEKLLMSVGRRPVTKGFGLENLNLDKTGRGAIKVNEKMQ 293
Query: 332 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGK 391
T++ G+Y GD+ +LAH A E V V I G +Y AIP V+YT+PE+ VG+
Sbjct: 294 TSLSGVYVCGDLTGFSLLAHTAVREAEVAVHSILGKEDAMSYRAIPGVVYTNPEIAGVGE 353
Query: 392 TEEDLKKEGRAYKVGKFPFLANSRAKTNGE-TEGFVKVLSDKTTDVILGTHIIGPGGGEL 450
TEE +G YKV K P + R E G KVL D+ + I+G H++G E+
Sbjct: 354 TEESASAKGITYKVVKLPMAYSGRFVAENEGVNGVCKVLLDE-QERIIGAHVLGNPASEI 412
Query: 451 INEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
I A A E G A +V HPT E REA
Sbjct: 413 ITLAGTAIELGLTAAAWKKVVFPHPTVGEIFREA 446
>UniRef50_Q8RDF1 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Thermoanaerobacter|Rep: Dihydrolipoyl dehydrogenase -
Thermoanaerobacter tengcongensis
Length = 461
Score = 289 bits (708), Expect = 1e-76
Identities = 169/456 (37%), Positives = 255/456 (55%), Gaps = 12/456 (2%)
Query: 29 THDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLY 88
T + DL VIG GPGGYVAAIKAA+ G KV EKD LGGTCLN GCIP+KA + +Y
Sbjct: 6 TREYDLAVIGGGPGGYVAAIKAAKKGAKVALFEKDK-LGGTCLNRGCIPTKAYARAAEVY 64
Query: 89 HMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAP 148
+ K K+ G + FD+ ++++ K V L GI L + NK+ + +
Sbjct: 65 GILKKA-KEFGFDIQINYFDYAQVVKRKDTIVGELVEGIKALLKANKIEVFNKEAKVDKE 123
Query: 149 NKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
V GEK + KNI+IA+GS P D K ++ S L + S+PK + +IG
Sbjct: 124 KNVIFEGEK----IKAKNIIIATGSSPAELPIEGIDSKNVLNSDTILEITSLPKSLCIIG 179
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
GVIG+E + + G +V +E + +I +D +V+ ++ K+G+K + V
Sbjct: 180 GGVIGMEFAFIMNQFGVEVYVVEMMPNILP-SLDKKVSSAVKFAAQKRGIKIYTSSTVEK 238
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
V++EG V + + G + + + D V +SIGR+ T +G V + D+ I V+
Sbjct: 239 VEEEGENSVVTIRS--GDDIKKISVDKVFVSIGRKLNTS-IG-PIVDLLEFDKKAIKVDE 294
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGW 388
+T + G++A+GDV MLAH A +G V V+ I G +Y IP+ ++T PE+G+
Sbjct: 295 HMRTNIEGVWAVGDVTGKMMLAHVASSQGEVAVDNIFGKSRTLDYYKIPAAVFTEPEIGY 354
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
G TEE+ K++ KVG+F F N RAKT GETEGF K++S + +V+ G ++G G
Sbjct: 355 FGYTEEEAKEKFGEIKVGRFDFKHNGRAKTYGETEGFAKIISTEDGEVV-GAWVVGSGAS 413
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
EL++ A + GA AE++ V +AHPT +E + EA
Sbjct: 414 ELVHIISTACQSGAKAEELKDVVYAHPTKSETIMEA 449
>UniRef50_Q0RVL5 Cluster: Dihydrolipoyl dehydrogenanse; n=1;
Rhodococcus sp. RHA1|Rep: Dihydrolipoyl dehydrogenanse -
Rhodococcus sp. (strain RHA1)
Length = 455
Score = 287 bits (705), Expect = 3e-76
Identities = 169/453 (37%), Positives = 246/453 (54%), Gaps = 15/453 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DLVVIGSGPGGYV+AI+ AQLG++ VE + LGG CLN CIP+KA+L + + +
Sbjct: 6 DLVVIGSGPGGYVSAIRGAQLGLRTAVVEGN-ALGGRCLNYACIPAKAVLRAADVLDEVR 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
H Q GI G F ++ + V LTGG+ L +KN V + G + V
Sbjct: 65 HA-SQFGIHVGTPRVSFDEVRARRDEVVASLTGGVRGLLKKNGVEVKHGWARLAGDGAVT 123
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVI 212
V GE TV+ + I++A+GS P PG+ F + +I + A +L+++P + V+GAG
Sbjct: 124 VDGE----TVHGRAIVLATGSVARPLPGLDFHGR-VIGTEQAWALDALPDTIAVVGAGAS 178
Query: 213 GLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKE 272
G+EL S Y RLG+ V IE I D +++ + L +QG+ G V ++
Sbjct: 179 GVELASAYARLGSKVRLIEASDRILPAE-DADISAIVHAKLRRQGIAISTGVTVSDTEQS 237
Query: 273 GSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQT 332
+ V+ G E ++++ GR P T L LD G+ LDDRG I V+ + +T
Sbjct: 238 TDAVSFTVD----GRTE--QTTWLVVAAGRSPDTDSLALDTAGVELDDRGLIRVDERLRT 291
Query: 333 TVPGIYAIGDVIHGPMLAHKAEDEGIVCVE-GIKGMPVHFNYDAIPSVIYTSPEVGWVGK 391
T PGI+AIGD++ GP LAHKA +EGI+ E + +P ++ IP + SP V VG
Sbjct: 292 TAPGIWAIGDLVRGPALAHKASEEGIIAAEDAAEHIPEPLLHNLIPRATFCSPSVASVGL 351
Query: 392 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 451
TEE +++G VG + A GE +G VK++ D +LG HI+G ELI
Sbjct: 352 TEEQARQQGYEVVVGTARYGAVGAGTVLGERDGLVKLVGDAKYGELLGAHIVGAKATELI 411
Query: 452 NEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
E V A+ A ++A + H HPT +EA+ EA
Sbjct: 412 QELVTARALEAGLPEIATIIHGHPTLSEAVSEA 444
>UniRef50_Q2GDU8 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Neorickettsia sennetsu str. Miyayama|Rep: Dihydrolipoyl
dehydrogenase - Neorickettsia sennetsu (strain Miyayama)
Length = 457
Score = 285 bits (699), Expect = 2e-75
Identities = 164/457 (35%), Positives = 250/457 (54%), Gaps = 10/457 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D++V+G GP GY AAI+A++ G+KV VEK+ LGG CLN GCIP+KALLH + YH K
Sbjct: 3 DVIVVGGGPAGYPAAIRASRSGLKVALVEKNK-LGGVCLNCGCIPTKALLHIAEKYHFVK 61
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ GI V F + Y +K L G++ L +KNKV L G I+ +V+
Sbjct: 62 TGAAELGINVSNVFLTFSSAIAYAQEKIKKLAAGVSYLMKKNKVELFYSSGRILPGKQVK 121
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVI 212
+ + G +T++ KNI++A+GS G+ +D + I A++ +PK +LV+GAG I
Sbjct: 122 LE-DLG-KTISAKNIILATGSTPKEITGLEYDHELIWNYNDAMTATKMPKSLLVVGAGAI 179
Query: 213 GLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKE 272
G+E +Y G+ VT IE I D E++ + + G+ + GT + +KK+
Sbjct: 180 GVEFACIYNVFGSKVTVIEMQNQILPAE-DTEISNLAEAAFKESGITIRKGTTIQSLKKD 238
Query: 273 GSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQT 332
KV V + G N EV + +L++ G ++ LGL+++ ++G + V+ +T
Sbjct: 239 KD--KVLVTLSDGTNLEV---ERILVAGGVEASSQNLGLEQIPTIRMNKGFVSVDKYCET 293
Query: 333 TVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGM-PVHFNYDAIPSVIYTSPEVGWVGK 391
PG+YAIGD+ P +AHKA + VC I G PV D+IPS IY+ P + VG
Sbjct: 294 GEPGVYAIGDLRGFPCVAHKAIYDAYVCTAKIAGKEPVPLEMDSIPSCIYSFPSIASVGL 353
Query: 392 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 451
TEE + G K+G+ N ++ G+ +G VK + D T +LG HIIG E++
Sbjct: 354 TEEAAIRMGHKVKIGRAKAEGNGKSVVLGKDKGLVKTVFDAKTGELLGAHIIGYEATEIL 413
Query: 452 NEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAA 488
N ++A+ A E + V HPT +E + EA LAA
Sbjct: 414 NGYIIAKASEATVESLKAVVFPHPTISEMMYEAVLAA 450
>UniRef50_A5N930 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Clostridium kluyveri DSM 555|Rep: Dihydrolipoyl
dehydrogenase - Clostridium kluyveri DSM 555
Length = 455
Score = 285 bits (698), Expect = 2e-75
Identities = 166/455 (36%), Positives = 256/455 (56%), Gaps = 13/455 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL+VIG+GPGG AA++AA+ GMK +EKD LGGTCLN GCIP KALLH++ +Y K
Sbjct: 6 DLIVIGTGPGGSAAALEAAKSGMKTAVIEKDK-LGGTCLNRGCIPMKALLHSAGIYQEIK 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
K+ GI+ + + +++YK + L+ G+ ML QKNKV++ G IV ++V
Sbjct: 65 ES-KKFGIQVEKAELNVPALLQYKEGVINKLSYGMEMLLQKNKVDVFYASGKIVNAHQVA 123
Query: 153 V--HGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
V +GEK + + + I+IASGS + P PG+ K ++TS L+ E + +++IG
Sbjct: 124 VSENGEKKI--IEAERIIIASGSSAVIPPIPGIQL--KNVVTSYELLNKEDLFHHLVIIG 179
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
GVIG+E S+Y G VT IE + + +D E+ L++IL KQG+ V
Sbjct: 180 GGVIGMEFASLYSAFGCRVTVIEAMNRVLP-DMDREIGTNLKQILKKQGVDIHTSASVEK 238
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
+++ K+ + + ++ D VL++IGR+P T+GL D+ ++G+I VN
Sbjct: 239 LEQTQEE-KILCTYREKEKLQHIEVDGVLVAIGRKPSTEGL-FDENFAVETEKGKILVNK 296
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGW 388
++T+ P IYAIGDVI G LAH A E + V I G + IP +YT+PE+
Sbjct: 297 YYKTSCPSIYAIGDVIGGIQLAHAASSEALCAVRHIIGKEESLDVRVIPGCVYTNPEIAV 356
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VG T K+ G K+P +AN ++ + GF+KV+++K T+ ILG ++
Sbjct: 357 VGITASQAKETGIDVITKKYPMMANGKSVLTMQERGFMKVVAEKETEKILGAQLMCARAT 416
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
++I++ A G +A V H HPT +E + E
Sbjct: 417 DIISQFTSAIVNGMTLSQMAHVIHPHPTFSEGIGE 451
>UniRef50_O66945 Cluster: Dihydrolipoyl dehydrogenase; n=2; Aquifex
aeolicus|Rep: Dihydrolipoyl dehydrogenase - Aquifex
aeolicus
Length = 465
Score = 280 bits (687), Expect = 5e-74
Identities = 162/467 (34%), Positives = 260/467 (55%), Gaps = 12/467 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDP-TLGGTCLNVGCIPSKALLHNSHLYHMA 91
DL+++G+G GGY A + A + GMKV VE P T+GG CLN GCIPSK + H ++L
Sbjct: 4 DLIIVGAGSGGYEAGLYAFRRGMKVAFVELSPETVGGNCLNRGCIPSKYMRHGAYLLDKF 63
Query: 92 KHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
+ +Q GI + ++KK+ E + N V + Q+ ++ + G G + PN V
Sbjct: 64 QK-MEQYGIISKGYDIEYKKLKEGRDNVVVTIRENFKKFAQQLRIPIYYGKGVLKDPNTV 122
Query: 152 EVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGV 211
V G + ET+ K IL+A+GS T + D K +I + ++ VPKK+L++G G
Sbjct: 123 FVEGPE--ETLKAKYILVATGSSPTSVGNLVPDGKYVIDTDQIWEIDYVPKKVLIVGGGA 180
Query: 212 IGLELGSVYQRLGADVTAIEFLTSIGGV-GIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
+G+E ++++ G++V +E + I + + L + L + G+ + T V +
Sbjct: 181 VGVEFAYIFRKYGSEVVLVEIKDRLLPTPDIPEDSGRYLARKLRELGVDIRTRTSVESWE 240
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
K + +K + EV+ D +L+ +GR+P TKG+GL+++GI +D+RG + N
Sbjct: 241 KTQNGVKAKLT----DGSEVV-ADFILLGVGRKPNTKGIGLEELGIEMDERGFVKTNEYA 295
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKG-MPVHFNYDAIPSVIYTSPEVGWV 389
QT +P IYA GD+ MLAHK+ EG + V I G N IP +IY++ EV V
Sbjct: 296 QTNIPNIYACGDITSPLMLAHKSMYEGKIAVSHILGERDWKKNERIIPKIIYSALEVASV 355
Query: 390 GKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGE 449
G TEE + E +VG F++N +A +GE EGFV++++D T ILG HI+GP GE
Sbjct: 356 GLTEEQAEDEDIEVRVGVASFVSNPKAMDDGENEGFVRIVADDETGEILGCHIVGPHAGE 415
Query: 450 LINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 496
LI++ V + G E ++ ++HP+ +E + A+ Y G PI++
Sbjct: 416 LIHQVVHMIKDGKTVEFASKTMYSHPSLSENIGIASSEVYYG-PISW 461
>UniRef50_Q9YBC8 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Desulfurococcales|Rep: Dihydrolipoyl dehydrogenase -
Aeropyrum pernix
Length = 464
Score = 279 bits (685), Expect = 9e-74
Identities = 172/468 (36%), Positives = 261/468 (55%), Gaps = 21/468 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLY-HMA 91
DLVV+G GPGGY AA++AAQ G+ V VE D +LGG C N GCIP+KALLH + L +A
Sbjct: 5 DLVVVGGGPGGYPAAVRAAQEGLNVALVEMD-SLGGECTNYGCIPTKALLHPAGLVASLA 63
Query: 92 KHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
+ F + G V DFK +ME+ + VKG++ G++ L + V +VKG I P V
Sbjct: 64 RLKFVK-----GSVDVDFKGLMEWVDSVVKGVSNGVSTLLKGYGVEVVKGRAKI-RPGVV 117
Query: 152 EVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGV 211
EV G ++ +++A G+ PG+ D + + + L L P +ML++G G
Sbjct: 118 EVDGSG---SIGYSKLVLALGTSPASIPGLEPDGEVVHNNRTILGLRRKPGRMLIVGGGY 174
Query: 212 IGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKK 271
IG+E + RLG +VT +E L + + + ++ +++ L +G+K +KV V++
Sbjct: 175 IGVEYATAMARLGVEVTIVELLDRLLP-NMQRDFSRVVERRLRAEGVKIHTKSKVEAVER 233
Query: 272 EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK-F 330
V+V G K ++ D +L+++GRRP T +GL+K+G+ LD G I V+
Sbjct: 234 RERYAVVEVS---GVGK--MEYDAILVAVGRRPNTGDVGLEKLGVKLDKAGYIQVDGATL 288
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKG-MPVHFNYDAIPSVIYTSPEVGWV 389
+T VPG+YA GDV P+LAH+A + +V E G F+ A+P+V+YT PE+ V
Sbjct: 289 ETGVPGVYASGDVTGPPLLAHRAFLQAVVAAERAAGDSSAAFDAKAVPAVVYTDPELATV 348
Query: 390 GKTEEDLKKEGRAYKVGKFPFLANSRAKT-NGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
G T E+ + G + P + R G E F KV+ D+++ ILG H+ P
Sbjct: 349 GLTLEEARAAGVDAAETRLPLASLPRVGAIEGCRECFAKVVYDRSSRAILGFHVAAPHAS 408
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 496
E+I EA LA E GA ED+A H HP+ +EAL+E A +PI++
Sbjct: 409 EIIAEAALAIEMGATLEDLALTIHPHPSVSEALKEVAELALE-RPIHY 455
>UniRef50_Q6KH64 Cluster: Pyruvate dehydrogenase E3 component
dihydrolipoamide dehydrogenase; n=2; Bacteria|Rep:
Pyruvate dehydrogenase E3 component dihydrolipoamide
dehydrogenase - Mycoplasma mobile
Length = 600
Score = 269 bits (660), Expect = 1e-70
Identities = 163/485 (33%), Positives = 257/485 (52%), Gaps = 20/485 (4%)
Query: 5 FLKLASPTFRSGSLVRIATRQYATTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDP 64
F K S T S + ++ + T D++V+GSGPGGY+AA +A + G K + +EK+
Sbjct: 118 FGKKTSSTPTSSTSIQPTSFNGKITDKYDVIVLGSGPGGYLAAEEAGKNGKKTLIIEKE- 176
Query: 65 TLGGTCLNVGCIPSKALLHNSHLYHMAKHDFKQR-GIETGEVTFDFKKMMEYKANAVKGL 123
GG CLNVGCIP+KALL ++ ++ H I+ ++ ++KKM E K V L
Sbjct: 177 YWGGVCLNVGCIPTKALLKSTEVFEQLSHASDYGLDIDVSKLKMNWKKMQERKQKVVNTL 236
Query: 124 TGGIAMLFQKNKVNLVKGVGTIVAPNKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTF 183
GG+ L + NKV + G +AP V+V+GE +NI+IA+GS+ F
Sbjct: 237 VGGVLALMKGNKVKTINGEAKFLAPKVVQVNGE----IYEAENIIIATGSKNRKLTLPGF 292
Query: 184 DEKQ----IITSTGALSLESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGV 239
+E IT+ A+ +ES+PK++++IG GVIG+E ++ G+ VT I+ +I
Sbjct: 293 EEAYKSGFAITAEEAIQIESLPKELVIIGGGVIGIEFAQIFAASGSKVTVIQNAPTIIPA 352
Query: 240 GIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLIS 299
+D +V K L L G++ + + ++K+ KV+ EA + + +++S
Sbjct: 353 -LDEDVIKVLSDKLISSGIQIVYNAETVKIEKDTLHYKVNGEA------KTIKASKIMVS 405
Query: 300 IGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIV 359
+GR P +VG + ++G I +N QT +PG YAIGDV MLAH A +
Sbjct: 406 VGRIPVIANA--KEVGYQIGEKGEIVINEFCQTNIPGAYAIGDVTFKTMLAHVAYQHAHI 463
Query: 360 CVEGIKGM-PVHFNYDAIPSVIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKT 418
++ + G + + +P+ IYT PE+ VG +E K+ GRAY K +A
Sbjct: 464 AIKHLLGNGDLSYTGKTVPACIYTHPEIASVGMSERQAKESGRAYISEKHQMKFIGKAIA 523
Query: 419 NGETEGFVKVLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCA 478
+ +T GF K++ DK T ILG HIIG +LI+E V+A + ++A H HPT +
Sbjct: 524 SDQTMGFSKLIIDKETHEILGAHIIGAHATDLISELVVAIDLETTVHEIANAIHPHPTFS 583
Query: 479 EALRE 483
E + E
Sbjct: 584 EIIWE 588
>UniRef50_Q2B857 Cluster: Dihydrolipoamide dehydrogenase; n=1;
Bacillus sp. NRRL B-14911|Rep: Dihydrolipoamide
dehydrogenase - Bacillus sp. NRRL B-14911
Length = 476
Score = 269 bits (660), Expect = 1e-70
Identities = 161/456 (35%), Positives = 238/456 (52%), Gaps = 7/456 (1%)
Query: 30 HDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYH 89
++ D+V+IG GPGGY AAI+AAQLG KV +EK LGG CL+ GCIPSK +
Sbjct: 8 YEKDVVIIGGGPGGYQAAIRAAQLGRKVTLIEK-ADLGGVCLHKGCIPSKLFAEAADRIR 66
Query: 90 MAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPN 149
K + GIE F +K+M K L G+ L + N++ LVKG ++ +
Sbjct: 67 KIKAA-GEYGIELSFSAFQLEKLMNEKDRKTAQLKKGVEELCKSNEIELVKGNAFFLSAD 125
Query: 150 KVEVHGEKGVETVNTKNILIASGSE-VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
++ + + + K+ LIA+GS + P EK ++ SL+ +P ++++ G
Sbjct: 126 RMGIENGEAYQVFRFKHCLIATGSTPIWPHDNSPRSEK-LLDCWSVFSLKKLPDELIIYG 184
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
+G I LE+ +Q GA T+I G D V + + +IL K +K G K+L
Sbjct: 185 SGYIALEMAMSFQAFGAR-TSIMLDQEKDDFGFDAAVNREIGRILKKNRIKVYRGAKLLS 243
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
V++ GS ++++ E GG + L L + G RP T LGLD+ G+ +D G I ++
Sbjct: 244 VEESGSGVEINYEL--GGENKQLKGSCFLTAAGFRPNTANLGLDRAGVEIDTAGFIKIDQ 301
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGW 388
+ +T+V I+A GDV GP LA KA +G E I G+ + P VI+T P + +
Sbjct: 302 QGKTSVSHIFAAGDVADGPPLASKAIRQGKAAAETIAGLKTEADLRFAPVVIHTQPPIAY 361
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
G TE++ + G G FPF + A G EG KV+ +K T +LG H+IG G
Sbjct: 362 AGLTEQEALEAGYKIDTGIFPFSSLGYASVKGSREGMAKVIFEKETGFLLGVHMIGDGAQ 421
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
ELI V E A ED+ +AHP+ AEAL EA
Sbjct: 422 ELICAGVSLLEMAAREEDMLFPVYAHPSSAEALLEA 457
>UniRef50_Q7MW44 Cluster: Dihydrolipoyl dehydrogenase; n=10;
Bacteroidales|Rep: Dihydrolipoyl dehydrogenase -
Porphyromonas gingivalis (Bacteroides gingivalis)
Length = 449
Score = 266 bits (652), Expect = 9e-70
Identities = 164/456 (35%), Positives = 247/456 (54%), Gaps = 20/456 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL +IG GP GY AA +AA+ G+K + +EK+ LGG CLN GCIP+K LL+++ + H
Sbjct: 4 DLAIIGGGPAGYTAAERAAKGGLKTLLIEKN-ALGGVCLNEGCIPTKTLLYSAKVLHQIA 62
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
K T + D K++ K ++ LT GI + V +V T+ +
Sbjct: 63 TASKYAVSGTAD-GLDLGKVIARKGKIIRKLTAGIRSRLTEAGVEMVTAEATVTGCDADG 121
Query: 153 VHG-EKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
+ G G N+L+ +GSE + P PGV ++ + T+ AL + +P +++IG
Sbjct: 122 IIGITAGEAQYKAANLLLCTGSETFIPPIPGV--EQTEYWTNREALQNKEIPTSLVIIGG 179
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
GVIG+E S + +G V +E L I GID E A L+ K+G+KF LG KV V
Sbjct: 180 GVIGMEFASFFNGIGTQVHVVEMLPEILN-GIDPEHAAMLRAHYEKEGIKFYLGHKVTSV 238
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
+ T++ + G +KE+ + + +L+S+GRRP +G + +G+ L +G + N +
Sbjct: 239 RNGAVTVEYE-----GESKEI-EGERILMSVGRRPVLQGF--ESLGLVLAGKG-VKTNER 289
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH-FNYDAIPSVIYTSPEVGW 388
QT++P +YA GD+ +LAH A E V V+ I G +Y A+P V+YT+PEV
Sbjct: 290 MQTSLPNVYAAGDITGFSLLAHTAVREAEVAVDQILGKTDETMSYRAVPGVVYTNPEVAG 349
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSR-AKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG+TEE L+K GRAY V + P + R N + G K+L D+ +I G H+IG
Sbjct: 350 VGETEESLRKAGRAYTVRRLPMAFSGRFVAENEQGNGECKLLLDEENRLI-GAHLIGNPA 408
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
GELI A +A E G + R+ HPT E L+E
Sbjct: 409 GELIVTAAMAIETGMTDRQIERIIFPHPTVGEILKE 444
>UniRef50_Q73M80 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Treponema denticola|Rep: Dihydrolipoyl dehydrogenase -
Treponema denticola
Length = 453
Score = 265 bits (650), Expect = 2e-69
Identities = 167/457 (36%), Positives = 251/457 (54%), Gaps = 26/457 (5%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLY-HMA 91
DL+V+G GPGGYVAAIKA + G+K +EK+ LGGTCLN GCIP+K LLH + ++ A
Sbjct: 3 DLIVLGGGPGGYVAAIKAGRAGLKTALIEKN-RLGGTCLNKGCIPTKYLLHTAEVFGSFA 61
Query: 92 KHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
++D G+ + +D K + E K V L GGI L + V+ G G I + + V
Sbjct: 62 ENDL---GLSGENLKYDIKAIYEKKNAVVDKLVGGIEKLIENAGVDFYNGEGKITSKSSV 118
Query: 152 EVHGEKGVETVNTKNILIASGSEV--TPFPGVTFDEKQIITSTGALSLESVP-KKMLVIG 208
V+G++ + KN++IA+GS V P G+ + +TS L E V K +++IG
Sbjct: 119 SVNGKE----LEFKNLIIATGSSVFAPPIAGI----ETAMTSDDILGKEPVDFKSVIIIG 170
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
GVIG+E +VY LG +VT +E +I D ++A +L K+G+K G V
Sbjct: 171 GGVIGIEFATVYANLGKEVTIVELEKTILPP-FDRDIAMQQAIVLKKRGVKIINGAMVTK 229
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
++K G T + + +E + D V++ IGR K +GLD GI D RG I +
Sbjct: 230 IEKTGCTFTLKEK------EESITADAVIVCIGRIAEIKDIGLDSAGIEYDKRGII-TDA 282
Query: 329 KFQTTVPGIYAIGDVIHGP-MLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVG 387
+T V GIYAIGD + G MLAH AE++G + VE I H D IPS +Y++PE+
Sbjct: 283 CMKTNVEGIYAIGDAVKGNVMLAHNAENQGHLVVENIVNNTKHEKQDVIPSCVYSTPEIA 342
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG +E++ + +G K+GK P +N ++ +G GF+KVL ++ D I+G ++
Sbjct: 343 GVGLSEKEAEAKGITVKIGKVPMGSNGKSVLSGLDVGFIKVLFNE-EDRIVGCQMMCDSA 401
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
++I A E++ + + HPT EA EA
Sbjct: 402 TDMIGAIGTLVTNKAKRENILKSMYPHPTVVEAFYEA 438
>UniRef50_Q02733 Cluster: Increased recombination centers protein
15; n=2; Saccharomyces cerevisiae|Rep: Increased
recombination centers protein 15 - Saccharomyces
cerevisiae (Baker's yeast)
Length = 499
Score = 265 bits (650), Expect = 2e-69
Identities = 166/476 (34%), Positives = 249/476 (52%), Gaps = 21/476 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D++VIG GPGG+ AA++A+Q G+ V++ +LGG L G +PSK LL+ S+LY + +
Sbjct: 19 DVLVIGCGPGGFTAAMQASQAGLLTACVDQRASLGGAYLVDGAVPSKTLLYESYLYRLLQ 78
Query: 93 HD--FKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
+QRG FD + + ++ L KN V + KG P+
Sbjct: 79 QQELIEQRGTRLFPAKFDMQAAQSALKHNIEELGNVYKRELSKNNVTVYKGTAAFKDPHH 138
Query: 151 VEVHGEKGVET--VNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
VE+ ++G++ V K I++A+GS V PGV D +II+S ALSL+ +P + ++G
Sbjct: 139 VEI-AQRGMKPFIVEAKYIVVATGSAVIQCPGVAIDNDKIISSDKALSLDYIPSRFTIMG 197
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV-L 267
G IGLE+ ++ LG+ VT +E + I +D E+A + +L QG+ F L T+V L
Sbjct: 198 GGTIGLEIACIFNNLGSRVTIVESQSEI-CQNMDNELASATKTLLQCQGIAFLLDTRVQL 256
Query: 268 GVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRG---RI 324
+ + + V CDV+++SIGRRP KGL + +G LD+R +
Sbjct: 257 AEADAAGQLNITLLNKVSKKTYVHHCDVLMVSIGRRPLLKGLDISSIG--LDERDFVENV 314
Query: 325 PVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVE--GIKGMPVHFNYDAIPSVIYT 382
V + P I IGDV GPMLA KAE++ I ++ G G N P+V+Y
Sbjct: 315 DVQTQSLLKYPHIKPIGDVTLGPMLALKAEEQAIRAIQSIGCTGSDGTSNCGFPPNVLYC 374
Query: 383 SPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKT------NGETEGFVKVLSDKTTDV 436
P++GWVG TEE L K Y+ G+ F N R T N F+KVL D
Sbjct: 375 QPQIGWVGYTEEGLAKARIPYQKGRVLFSQNVRYNTLLPREENTTVSPFIKVLIDSRDMK 434
Query: 437 ILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA-NLAAYSG 491
ILG H+I EL+++A +A G A DV +V HP+ +E+ ++A LA +G
Sbjct: 435 ILGVHMINDDANELLSQASMAVSLGLTAHDVCKVPFPHPSLSESFKQAVQLAMANG 490
>UniRef50_A7BC28 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 455
Score = 262 bits (642), Expect = 1e-68
Identities = 167/461 (36%), Positives = 250/461 (54%), Gaps = 27/461 (5%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D++V+G+GPGGY+AA + G KV VE+ LGGTCLNVGCIP+K LL+ + Y AK
Sbjct: 7 DVIVLGAGPGGYLAAERLGHAGKKVALVEEQ-YLGGTCLNVGCIPTKTLLNGAKNYLHAK 65
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ Q G++ V ++ +M +K VKGL G+A +K V ++ G G + AP +V
Sbjct: 66 -EASQFGVDAQGVAVNWTQMQAWKDQVVKGLVAGVAATERKAGVTVINGRGHLDAPGRVT 124
Query: 153 VHGEKGVETVNTKNILIASGS--EVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
V G T + +++IA+GS + P PG T D ++ STG LSL +P ++ +IG G
Sbjct: 125 VEGT----TYTSDHVIIATGSVPAMPPLPG-TQDNPALVDSTGILSLPQIPARLAIIGGG 179
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
VIG+E S+Y LG+ VT IE I D AK + + + F+LG +V +
Sbjct: 180 VIGVEFASLYATLGSQVTVIEMAPEILPFMDDDLAAKAR---AAMKDVTFELGCRVESL- 235
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
+G T V +KG K ++ DVVL+++GRRP T+G G + G+ + +RG + V++
Sbjct: 236 -DGGT----VHYSKGEEKLSVEADVVLMAVGRRPATEGWGAQEAGLEI-NRG-VVVDDTM 288
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI-----KGMPVHFNYDAIPSVIYTSPE 385
+T +P ++AIGDV +LAH A + I K + +P +++ PE
Sbjct: 289 RTNLPNVWAIGDVTGRSLLAHAAYRMAEIASANILDPSAKKRGEVMRWHTVPWAVFSIPE 348
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSR--AKTNGETEGFVKVLSDKTTDVILGTHII 443
VG TE K+EGR V K P L + R A+ + G K+L D T +LG H++
Sbjct: 349 AAGVGLTESAAKREGREVLVAKVPALMSGRFIAENGFKAPGEAKILVDPKTHQVLGIHVL 408
Query: 444 GPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
G E+I A E ED+ +V HPT +E +REA
Sbjct: 409 GAYAAEMIWGAQAVLEMELTVEDLRQVVFPHPTVSEVIREA 449
>UniRef50_Q97CK3 Cluster: Dihydrolipoyl dehydrogenase; n=4;
Thermoplasmatales|Rep: Dihydrolipoyl dehydrogenase -
Thermoplasma volcanium
Length = 436
Score = 262 bits (642), Expect = 1e-68
Identities = 162/465 (34%), Positives = 255/465 (54%), Gaps = 34/465 (7%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D VV+G+GPGGY AAI+ Q KV +EKD +GG CLN GCIPSKA++ ++ + K
Sbjct: 3 DAVVLGAGPGGYAAAIRLGQRKKKVAIIEKDK-IGGECLNYGCIPSKAIIELANSINYLK 61
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ G+ D KK E+K + + LTGG+ +L + V++ +G G I N V+
Sbjct: 62 ---EMPGVSIN-YNVDMKKWQEWKWSMINKLTGGVELLLKAYGVDIFRGTGYIQDKNHVK 117
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVI 212
V+ + + T +++IA+GS+ G+ ++ + L L+ +P +++IG G I
Sbjct: 118 VNDK----VLETDSLVIATGSKPVSINGIN----DVMYNREVLDLDHIPSSIVIIGGGYI 169
Query: 213 GLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKE 272
G+E+G +LG+ VT +E + SI G D E+ + + + +S+ G+ G KVL K
Sbjct: 170 GVEIGIALAKLGSKVTIVEMMPSILP-GTDNELVRHVVRRMSQLGINVITGRKVLSTAKN 228
Query: 273 GS-TIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQ 331
G T+K+D + + L + VL+++GR P T+G GL+ + +A+D R I +++
Sbjct: 229 GEVTVKLD-------DGQELRAEKVLMTVGRIPNTEGFGLENLKLAMDGRF-IKTDSRKM 280
Query: 332 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGK 391
T+V G+YAIGDV PMLAHKA E + + I G+ +Y A+P VIY+ PE+ + G
Sbjct: 281 TSVKGVYAIGDVSGQPMLAHKAYYEADIAADNICGIDSEVDYRAMPYVIYSDPEIAYTGV 340
Query: 392 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 451
+ K +FP AN R+ T E G + D+ ++ G I P ELI
Sbjct: 341 ---------KGAKSTRFPVAANGRSLTMNENIGTFNIYYDE-KGIVTGAGIAAPHASELI 390
Query: 452 NEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 496
+E LA E G A D+ H HPT +E ++E+ Y GKP++F
Sbjct: 391 SEISLAVESGLMAMDIGLTIHPHPTVSEGVKESAEEVY-GKPLHF 434
>UniRef50_Q8ZUR5 Cluster: Pyruvate dehydrogenase E3; n=2;
Pyrobaculum|Rep: Pyruvate dehydrogenase E3 - Pyrobaculum
aerophilum
Length = 452
Score = 262 bits (642), Expect = 1e-68
Identities = 159/463 (34%), Positives = 258/463 (55%), Gaps = 18/463 (3%)
Query: 34 LVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAKH 93
+VV+G GP GYVAAI+A QLG+ V VE + LGG C N CIPSKALLH + Y A
Sbjct: 3 VVVVGGGPAGYVAAIRARQLGLDVTLVEAE-RLGGECTNYACIPSKALLHAAEAYRRA-- 59
Query: 94 DFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVEV 153
I TG V+F +K+ +++K V+ L GI L V +V+G+ VE+
Sbjct: 60 -VSSPWI-TGTVSFRWKEAVQWKEKVVEKLRRGIEFLLSAAGVEVVRGLAKPGPGKTVEI 117
Query: 154 HGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVIG 213
G + + +++A+GSE + F +++I + SLE P + +IG G G
Sbjct: 118 DGRR----LQYDFLILATGSEPVGLKELPFG-RRVIGTREIFSLEEPPASVAIIGGGASG 172
Query: 214 LELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVL-GVKKE 272
+E+ S++ +GA+V +E + I G+D E+++ +++ LS +G+K ++V+ G + E
Sbjct: 173 VEIASLFSMIGAEVHVVEAMERILP-GLDPEISRQMERALSSRGVKIYTSSRVVKGEEGE 231
Query: 273 GSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQT 332
GS +K+ + ++ GG +E+ + ++ ++++GRRP + +G+ +D RG + V+ +T
Sbjct: 232 GS-VKLRI-SSPGGEREI-EAELAVVAVGRRP--RPGPFSAMGLEVDGRGAVRVDESMRT 286
Query: 333 TVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGKT 392
+VP ++A GDV P AHKA + V E I G+ ++ ++P+VI++ PEV VG T
Sbjct: 287 SVPWVFAAGDVTGPPYFAHKAYAQAKVAAEAIAGLKSAYSPRSVPAVIFSDPEVVSVGMT 346
Query: 393 EEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELIN 452
EE+ +G K + A +A GF K++ D + +ILG HI+G G EL
Sbjct: 347 EEEAVAKGYRPKAVRMSLSALGKAVAAESEGGFAKLIYDAESRIILGVHIVGRGVSELAG 406
Query: 453 EAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
EA E+ A +D+A H HPT +E E AA GKP++
Sbjct: 407 EASALVEFYATVDDLALTIHPHPTLSELFAELAEAAL-GKPVH 448
>UniRef50_Q4L6L9 Cluster: Dihydrolipoyl dehydrogenase; n=16;
Staphylococcus|Rep: Dihydrolipoyl dehydrogenase -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 474
Score = 261 bits (639), Expect = 3e-68
Identities = 171/467 (36%), Positives = 247/467 (52%), Gaps = 21/467 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DLV++G G GYVAAI+A+QLG KV VEK LGGTCL+ GCIP+KALL ++ + K
Sbjct: 7 DLVILGGGTAGYVAAIRASQLGNKVAIVEKS-LLGGTCLHKGCIPTKALLKSAEVLRTVK 65
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIV-----A 147
D G+ G+ +FD K MM+ K V + GI L QKN +++ G G I+ +
Sbjct: 66 -DSVHFGVNVGQYSFDLKSMMKRKDKIVNQMHQGIESLMQKNHIDIFNGTGRIMGTSIFS 124
Query: 148 PNKVEVHGE-KGVET--VNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKM 204
P + E VE+ + +N+LIA+GS T P + F+ +++S L L +P +
Sbjct: 125 PQSGTISVEYDNVESELLPNQNVLIATGSLPTQLPFLPFNHNTVLSSNDILQLTDLPASI 184
Query: 205 LVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKF--KL 262
+IG GVIGLE S+ LG +V+ IE I ++A L+ L +G+ F
Sbjct: 185 AIIGGGVIGLEFASLLIDLGVNVSVIEAGERILP-NESAQIANFLKTSLIARGVTFYENC 243
Query: 263 GTKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRG 322
VK +++ + V K ++ + VL+SIGR+P T +GL+ I DD G
Sbjct: 244 ALNESAVKVNSNSVTIQVNKDK-----TIEVEKVLVSIGRKPNTDDIGLNNTKIKTDDNG 298
Query: 323 RIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIY 381
I VN+ QT IYA GD I LAH + E I+ VE + G + NYD +P IY
Sbjct: 299 NILVNDFLQTEDKHIYAAGDCIGKLQLAHVSSKEAILAVEHMFNGNGLPLNYDKMPKCIY 358
Query: 382 TSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGET--EGFVKVLSDKTTDVILG 439
T PEV +G +E + + K K F A +A T GF +++ + T+ I+G
Sbjct: 359 THPEVASIGYNKESAEAKNIKTKSFKVSFNAIGKAVIEETTNDRGFCEMIINDETNEIIG 418
Query: 440 THIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANL 486
++IGP ELINEA L Q +A ++ HAHP+ +E L E L
Sbjct: 419 INMIGPQVTELINEASLLQFMNGSAIELGLTTHAHPSISEVLMELGL 465
>UniRef50_P16171 Cluster: Mercuric reductase (EC 1.16.1.1) (Hg(II)
reductase); n=46; Bacteria|Rep: Mercuric reductase (EC
1.16.1.1) (Hg(II) reductase) - Bacillus cereus
Length = 631
Score = 260 bits (638), Expect = 5e-68
Identities = 156/461 (33%), Positives = 243/461 (52%), Gaps = 15/461 (3%)
Query: 30 HDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYH 89
+D D ++IGSG + +AI+A L KV +E+ T+GGTC+NVGC+PSK LL + H
Sbjct: 168 YDYDYIIIGSGGAAFSSAIEAVALNAKVAMIERG-TVGGTCVNVGCVPSKTLLRAGEINH 226
Query: 90 MAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGG-IAMLFQKNKVNLVKGVGTIVAP 148
+AK++ G+ T D +++ K + V + L L+KG V
Sbjct: 227 LAKNN-PFVGLHTSASNVDLAPLVKQKNDLVTEMRNEKYVNLIDDYGFELIKGESKFVNE 285
Query: 149 NKVEVHGEKGVETVNTKNILIASGSEVTP--FPGVTFDEKQIITSTGALSLESVPKKMLV 206
N VEV+G + + K LIA+G+ T PG+ DE +TST L L+ VP ++ V
Sbjct: 286 NTVEVNGNQ----ITAKRFLIATGASSTAPNIPGL--DEVDYLTSTSLLELKKVPNRLTV 339
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
IG+G IG+ELG ++ LG++VT I+ + D E+++ + K L++QG+ G
Sbjct: 340 IGSGYIGMELGQLFHNLGSEVTLIQRSERLLKE-YDPEISEAITKALTEQGINLVTGATY 398
Query: 267 LGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPV 326
V+++G KV VE G K +++ + +LI+ GR+P L L G+ + RG I +
Sbjct: 399 ERVEQDGDIKKVHVEI--NGKKRIIEAEQLLIATGRKPIQTSLNLHAAGVEVGSRGEIVI 456
Query: 327 NNKFQTTVPGIYAIGDVIHGPMLAHKAEDEG-IVCVEGIKGMPVHFNYDAIPSVIYTSPE 385
++ +TT IY+ GDV GP + A EG + I G+ N + +P V +TSP
Sbjct: 457 DDYLKTTNSRIYSAGDVTPGPQFVYVAAYEGGLAARNAIGGLNQKVNLEVVPGVTFTSPS 516
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGP 445
+ VG TE+ K++G K P A RA N ET G K+++D T +LG H++
Sbjct: 517 IATVGLTEQQAKEKGYEVKTSVLPLDAVPRALVNRETTGVFKLVADAKTLKVLGAHVVAE 576
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANL 486
G++I A LA ++G D+ + T AE L+ A L
Sbjct: 577 NAGDVIYAATLAVKFGLTVGDLRETMAPYLTMAEGLKLAVL 617
>UniRef50_A3EPX8 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep: Dihydrolipoyl
dehydrogenase - Leptospirillum sp. Group II UBA
Length = 462
Score = 260 bits (636), Expect = 8e-68
Identities = 153/453 (33%), Positives = 242/453 (53%), Gaps = 8/453 (1%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DLVV+G GP GYV AI+AA LGMKV VE D +GGTCL+ GCIP+K LL +
Sbjct: 6 DLVVVGGGPAGYVGAIRAAHLGMKVGLVESDK-VGGTCLHEGCIPTKVLLEAAGFVSQVA 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ G+ G + D+K + ++ V L GI L +KN + G G +V+P +V
Sbjct: 65 RS-GEFGVSVGVPSVDWKTLSAHREKVVSRLFLGIQALLRKNGILHFSGEGQLVSPEEVF 123
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVI 212
V G + + + +IL+A+GS P+PG+ FD ++++ ST AL L ++ ++G GV+
Sbjct: 124 VSGGEN-KKLRASHILVATGSRPRPWPGLPFDRERVLDSTDALRLSPAGHRIGIVGGGVV 182
Query: 213 GLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKE 272
G+E ++Q G DVT +E + + D ++ L+K ++GM + G + ++
Sbjct: 183 GVEFADIFQSFGGDVTLLEKEERLLPLE-DPDLVDILRKEYERRGMSIRTGVSIETIEVG 241
Query: 273 GSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQT 332
+K+ G K+ L D +L++IGR G G+ ++ RG + V+ T
Sbjct: 242 PEGVKIT--GVDGSGKKELVFDKLLVAIGREARLPAFGKGFSGLPME-RGFLKVDPYGWT 298
Query: 333 TVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGM-PVHFNYDAIPSVIYTSPEVGWVGK 391
+ G+YA GDV G MLAH A + ++ V+ + G P F+ +P V+Y+ PEV VG
Sbjct: 299 GLSGLYAAGDVTGGLMLAHAASHQAVIAVDRMAGKNPSPFDPSHVPRVVYSHPEVVSVGI 358
Query: 392 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 451
+ ++ +++G + + G++P L N R+ +GE G V+V D T +LG +G G ELI
Sbjct: 359 SGQEARRKGLSVRQGEYPLLGNGRSLIHGEKRGLVRVFGDPETGRVLGLAGVGAGLSELI 418
Query: 452 NEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
+ LA + HPT EAL EA
Sbjct: 419 SLGTLAMQTPQGLLAFQGTIIPHPTVGEALWEA 451
>UniRef50_Q82L58 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Streptomyces avermitilis|Rep: Dihydrolipoyl
dehydrogenase - Streptomyces avermitilis
Length = 478
Score = 258 bits (633), Expect = 2e-67
Identities = 152/465 (32%), Positives = 253/465 (54%), Gaps = 15/465 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D++VIG G GGY AA++AA LG+ VV E+D +GGTCL+ GCIPSKA+LH + L
Sbjct: 8 DVIVIGGGTGGYSAALRAAALGLTVVLAERDK-VGGTCLHRGCIPSKAMLHAAELVDGIA 66
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
++ G++ D+ ++ + + V G+ +V +V+G + P V
Sbjct: 67 EARERWGVKATLDDIDWPALVATRDDIVTRNHRGVEAHLAHARVRVVRGSARLTGPRSVR 126
Query: 153 VHGEK------GVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLV 206
V G + + I++A+GS PG+ D ++++TS AL +P+ +LV
Sbjct: 127 VEGAPDDLPGGAGDFTARRGIVLATGSRPRTLPGLVPDGRRVVTSDDALFAPGLPRSVLV 186
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
+G G IG+E S ++ +GA+VT +E I + D +V++ L + L K+G+ + G ++
Sbjct: 187 LGGGAIGVEYASFHRSMGAEVTLVEAADRIVPLE-DVDVSRHLTRGLKKRGIDVRAGARL 245
Query: 267 LGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPV 326
L + + ++ V + G L+ + +L+++GR P T GL L G+A D+RG +
Sbjct: 246 LDAELLEAGVRARVRTVR-GEIRTLEAERLLVAVGRAPVTDGLDLAAAGLATDERGFVTP 304
Query: 327 N--NKFQTTVPGIYAIGDVIHGPM--LAHKAEDEGIVCVEGIKGMP-VHFNYDAIPSVIY 381
+ ++ +T VPGI+ +GD++ P LAH + EG+ E + G+P +Y A+P V Y
Sbjct: 305 SDWDRLETAVPGIHVVGDLLPPPSLGLAHASFAEGLSVAETLAGLPSAPVDYAAVPRVTY 364
Query: 382 TSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTH 441
+SP+ VG E + + G V P A ++ +G G VKV++++ +LG H
Sbjct: 365 SSPQTASVGLGEAEARARGHEVDVNTMPLTAVAKGMVHGR-GGMVKVVAEEGGGQVLGVH 423
Query: 442 IIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANL 486
++GP E+I E+ L + A DVAR HAHPT +EA+ E L
Sbjct: 424 LVGPHVSEMIAESQLIVGWDAQPSDVARHIHAHPTLSEAVGETFL 468
>UniRef50_Q746U4 Cluster: Mercuric reductase; n=5; Geobacter|Rep:
Mercuric reductase - Geobacter sulfurreducens
Length = 468
Score = 256 bits (626), Expect = 1e-66
Identities = 153/454 (33%), Positives = 238/454 (52%), Gaps = 13/454 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL+++GSG + AA++A G +V+ VEK LGGTC+N GC+PSK L+H + Y +
Sbjct: 6 DLIILGSGSTAFAAALRAHSRGARVLMVEKS-VLGGTCINWGCVPSKTLIHGALFYQEGR 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGL--TGGIAMLFQKNKVNLVKGVGTIVAPNK 150
+ E G D +M K VK L T + +L + L KG G + +
Sbjct: 65 LGARLGLGECGNAV-DLAPLMTRKEEVVKHLRTTRYLDILRNTPGLELAKGTGRFLGSGR 123
Query: 151 VEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
+EV + V + + + + PG+ + +TS GAL L+ P +++IG G
Sbjct: 124 LEVVDQ--VYRCDRYLVAVGGTPRIPKIPGL--ESTPFLTSRGALLLKRFPASLIIIGGG 179
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
VI +ELG ++QRLG VT +E I I+ E A ++ +L +GM+ + V V
Sbjct: 180 VIAVELGQMFQRLGTRVTILEHGPRILAP-IEPEPALAIRNVLRDEGMEIICHSPVCAVS 238
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
+GS + V+VE G + + +L+++G P T+G+GL+ G+ D RG + V+ +
Sbjct: 239 GDGSAVSVEVEREDG--RRTYTAEKLLLAVGTTPATRGIGLELAGVETDGRGFVTVDERM 296
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI--KGMPVHFNYDAIPSVIYTSPEVGW 388
+TT PGI+A GD G M+A EGI+ V+ + G ++ ++P I+T PEVG
Sbjct: 297 RTTAPGIWAAGDCTGGMMIATVGAREGIIAVDDMFATGCGCAMDHLSVPMAIFTDPEVGA 356
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VG TE+ + G V P A +A G T G +K+++++ T +LG H+ G
Sbjct: 357 VGYTEQGARDAGLDPIVSILPVSAIPKAHVTGHTAGVIKLVAERATGRLLGAHLACHRGA 416
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALR 482
ELINEA LA A ED+A H +P+ E LR
Sbjct: 417 ELINEAALAIRLKATFEDLANALHVYPSIGEGLR 450
>UniRef50_Q6ARJ3 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Desulfotalea psychrophila|Rep: Dihydrolipoyl
dehydrogenase - Desulfotalea psychrophila
Length = 479
Score = 255 bits (624), Expect = 2e-66
Identities = 159/462 (34%), Positives = 244/462 (52%), Gaps = 16/462 (3%)
Query: 34 LVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAKH 93
+VV+G+GPGGYVAAI+AAQLG V +EK+ +GGTCLN GCIPSK ++ + K
Sbjct: 10 IVVLGAGPGGYVAAIRAAQLGGDVTVIEKE-NVGGTCLNWGCIPSKIYKQSADTLNSIKD 68
Query: 94 D--FKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
F GI G++ + ++ E + + GI L KN ++ + G + + +
Sbjct: 69 SASFCIDGISEGKLNLE--RLQERTKGIIASQSKGIHGLLAKNSISYIGGEAKMSGSHSL 126
Query: 152 EVHGEKG-VETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
V + G E V ++IA+GS P + FD +I++S SL+ +P+ + +IG G
Sbjct: 127 SVTRKDGETEEVQFDKLIIATGSTPMALPFLPFDGDRILSSDHIFSLKEIPESITIIGGG 186
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGV-GIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
VIG E + Q G +VT +E L + + ++ E +K L + + K+ +K +L T +
Sbjct: 187 VIGCEFACILQSFGVEVTLVEGLERLLPLPSVEEECSKLLLREMKKKKIKVELKTTLASA 246
Query: 270 KKEGSTIKVD-VEAAKGGNKEV--LDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPV 326
++ ++++ V K G ++ ++ + VL+ IGRR + L LD+ G+ RG I
Sbjct: 247 SQKNGMVQLNLVSQGKNGTEKAKQIESEKVLVCIGRRASSASLDLDQAGVETTKRGWIST 306
Query: 327 NNKFQTTVPGIYAIGDVIHGP---MLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTS 383
QTTVP IYAIGDV+ GP MLAH A E + E G N+ +PS I+T
Sbjct: 307 GANLQTTVPHIYAIGDVL-GPERIMLAHTASTEAEIAAENCFGGAEEMNWQVMPSAIFTM 365
Query: 384 PEVGWVGKTE-EDLKKEGRA-YKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTH 441
PE+G VG +E + + G+ + F +A+ GE G K++ K ILG H
Sbjct: 366 PEIGCVGLSEAQAAELYGKENIRAESSLFRTLGKAQVIGELAGVTKIVCAKEDGKILGIH 425
Query: 442 IIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
I G +L+ EA LA G A+ + + HAHPT AE L E
Sbjct: 426 IAGAHATDLLGEATLAVSNGITAKQLTKTIHAHPTLAEILLE 467
>UniRef50_Q8DTC8 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Streptococcus|Rep: Dihydrolipoyl dehydrogenase -
Streptococcus mutans
Length = 445
Score = 254 bits (623), Expect = 3e-66
Identities = 158/454 (34%), Positives = 253/454 (55%), Gaps = 23/454 (5%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL++IG+GPGGY+AA +AA+LG KV VEK +GGTCLNVGCIPSKA L +SH + ++
Sbjct: 5 DLLIIGAGPGGYIAAEEAARLGKKVAVVEKKD-IGGTCLNVGCIPSKAYLQHSH-WLLSM 62
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ + GI T + DF K++ K V L GGI F+ K++ +G +
Sbjct: 63 QEANKYGISTNLESVDFAKLVNRKDQVVSTLQGGIHTTFKSLKIDYYEGQAQFLKDKSFM 122
Query: 153 VHGEKGVETVNTKNILIASGSEVTPF-PGVT-FDEKQIITSTGALSLESVPKKMLVIGAG 210
V+GEK ++ K++++A+GS PF P + + +T+ +L+ +P+K+++IG G
Sbjct: 123 VNGEK----ISGKDVILATGSH--PFIPQIHGINSVNYLTTDSFFNLKVLPEKLVIIGGG 176
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
VI +EL Q LG +VT IE I + D ++K L G K+ V
Sbjct: 177 VIAIELAFAMQPLGVNVTVIEIAPQIL-LTEDKAARAIIRKKLKTMGAHIFEAAKIEEVH 235
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
+ ++ D G +E D +L++ GR+P T+ ++G+ L +RG + V++ +
Sbjct: 236 AQSVILEGD------GAQEF---DQLLVATGRKPNTELA--QEMGLKLTERGFVKVDDYY 284
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPEVGWV 389
+T+ P +YAIGD+ MLAH A EGI V I + + +P +YT+PEV
Sbjct: 285 ETSTPHVYAIGDLTESYMLAHVASMEGIKAVRAICRQAQDPVDAQGVPRSLYTNPEVASF 344
Query: 390 GKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGE 449
G +EE+ K++G V + PF N RA + ET+GFVK++S++ ILG I+G G +
Sbjct: 345 GLSEEEAKEQGYDVLVEQLPFSFNGRAIASTETQGFVKLISERRYHQILGAVIVGEHGTD 404
Query: 450 LINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
L+ + +L ++ + V +AHPT +E ++E
Sbjct: 405 LLQQLILLRQAEGTFDQVVDAVYAHPTISELIQE 438
>UniRef50_Q1VLA0 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Psychroflexus torquis ATCC 700755|Rep: Dihydrolipoyl
dehydrogenase - Psychroflexus torquis ATCC 700755
Length = 432
Score = 252 bits (617), Expect = 2e-65
Identities = 160/442 (36%), Positives = 240/442 (54%), Gaps = 19/442 (4%)
Query: 55 MKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAKHDFKQRGIETGEVTFDFKKMME 114
++V VE D LGGTCLN GCIP+K LH + L H + GI + D+ K
Sbjct: 5 LEVTLVESD-VLGGTCLNRGCIPAKYWLHVAELNHEISTS-ENYGINIEGKSIDWNKTAL 62
Query: 115 YKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVEVHGEKGV-ETVNTKNILIASGS 173
+ V+ L GI +L + VN+++G G+I N V V G E + + I++A+GS
Sbjct: 63 KRIEVVEKLVSGIKLLLKSKDVNVIEGWGSIENKNSVLVKKSDGTTEKIESDYIILATGS 122
Query: 174 EVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFL 233
+ P + DE I+TS AL+ E PKK+ ++GAG IG E S+ LG++ T +E
Sbjct: 123 KPRNLPNIELDENFIVTSDSALNWEEPPKKVCIVGAGAIGCEFASLLNDLGSEATVVEMA 182
Query: 234 TSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKEGSTIKVDVEAAKGGNKEVLDC 293
I G+D + L+K LSK+G+ FKL + + + EG+T+ G K+ DC
Sbjct: 183 KEI-LPGLDKRTSGELRKQLSKRGVDFKLDSSIEAI--EGNTVNF-----SDGEKKEYDC 234
Query: 294 DVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVN-NKFQTTVPGIYAIGDVIHG-PMLAH 351
VLI++GR P T+ +GL+ V I+L++ G I V+ + FQT+V I+A+GD+++ P LAH
Sbjct: 235 --VLIAVGRAPLTENIGLENVNISLEN-GFINVDLDTFQTSVENIFALGDIVNNTPQLAH 291
Query: 352 KAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPF 410
A E I V I G +Y+AIP V+YT PE+ VG E K E + + F
Sbjct: 292 AAFAEAISSVTYIASGEKKPLDYNAIPYVVYTRPELAEVGLNAEKAKSENIEVEQAQHSF 351
Query: 411 LANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARV 470
RA + +G VKV + K ++ G + GP GE+I+E + + A ++ A
Sbjct: 352 AGVGRAMITEQNQGLVKVYAKKDGPIV-GASVCGPSAGEMIHEIMYMVGWEALPDEAAEF 410
Query: 471 CHAHPTCAEALREANLAAYSGK 492
HAHPT +EA+ E +L +GK
Sbjct: 411 IHAHPTLSEAVGE-SLLGLTGK 431
>UniRef50_Q8CQA3 Cluster: Dihydrolipoyl dehydrogenase; n=4;
Staphylococcus|Rep: Dihydrolipoyl dehydrogenase -
Staphylococcus epidermidis (strain ATCC 12228)
Length = 469
Score = 251 bits (615), Expect = 3e-65
Identities = 168/462 (36%), Positives = 245/462 (53%), Gaps = 24/462 (5%)
Query: 26 YATTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNS 85
Y + DL+VIG+GPGGYVAAI+ AQLG V +EK+ GGTCLNVGCIPSK LL +
Sbjct: 18 YYMSKSYDLIVIGAGPGGYVAAIRGAQLGKNVAVIEKN-NAGGTCLNVGCIPSKTLLEHG 76
Query: 86 HLYHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTI 145
H + GI T ++ DF + ++ K V+ LTGG+ L +KNKV ++G I
Sbjct: 77 EKAHSIRVA-NDWGITTKDLKIDFTQFVQRKKKVVQTLTGGVKQLLKKNKVTYIEGEARI 135
Query: 146 VAPNKVEVHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKK 203
KV+V+ E T K+I++A+GS+ + P G+ D+ T+ LE +PK+
Sbjct: 136 SKNLKVDVNNE----TYQAKDIILATGSQPFIPPIDGL--DQVNYETTDTFFDLEKLPKQ 189
Query: 204 MLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLG 263
+ VIG GVI EL S LG VT IE I I+ E + L+ L QG+K
Sbjct: 190 LAVIGGGVIATELASSMADLGVRVTIIEVADDILLTEIN-ETREMLKAHLDNQGIKILTK 248
Query: 264 TKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGR 323
K+ VK+ S I +D G +V D +L++ GR+P T+ + D + + +D +
Sbjct: 249 AKIKQVKE--SKIILD------GQDDV-SFDTLLVATGRQPNTQ-VAKD-LNLEMDGKF- 296
Query: 324 IPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKG-MPVHFNYDAIPSVIYT 382
VN ++T+ +YAIGD+I G LAH A GI VE I P + I IYT
Sbjct: 297 FKVNEHYETSQKHVYAIGDLIKGYQLAHAASAHGIHVVETIMNKQPSLVRQEDITRCIYT 356
Query: 383 SPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHI 442
E VG +E K+ G KV + F N++A GE EGF+K++ DK +LG I
Sbjct: 357 RLEAASVGLSEAQAKEAGYDVKVTQSAFQGNAKALIKGENEGFIKLVVDKKYGEVLGAFI 416
Query: 443 IGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
+GP ++I E + + +++++ HP EA+ E+
Sbjct: 417 VGPHATDIIGELLSVKASEGTIHELSQIIQPHPALLEAIGES 458
>UniRef50_Q5QYX3 Cluster: Mercuric reductase, membrane-associated;
n=35; Bacteria|Rep: Mercuric reductase,
membrane-associated - Idiomarina loihiensis
Length = 730
Score = 251 bits (615), Expect = 3e-65
Identities = 166/471 (35%), Positives = 254/471 (53%), Gaps = 28/471 (5%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
D +LVVIG+G G V+A AA + KV +EK +GG CLN GC+PSKALLH + L H
Sbjct: 237 DNNLVVIGAGSAGLVSAYIAATVKAKVTLIEKHK-MGGDCLNTGCVPSKALLHVAELAHN 295
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAM-LFQKNKVNLVKGVGTIVAPN 149
A++ G+ GEV+ DFK++M+ + +K + ++ + K V++ +G IV+P
Sbjct: 296 ARNA-SSAGVHVGEVSVDFKQVMQQVKSVIKDIEPHDSVERYTKLGVDVEQGDARIVSPW 354
Query: 150 KVEV----HGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKK 203
+VEV G+ + + T++I+IA+G++ V F G+ D+ +TS L+ +PK+
Sbjct: 355 EVEVTSNVEGKSETKRITTRSIIIATGAKPLVPDFEGL--DKVDYLTSDTLWELDELPKR 412
Query: 204 MLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLG 263
+LV+G G IG EL +QRLG+ VT +E + G D + + L + L+ +G+ +L
Sbjct: 413 LLVLGGGPIGCELSQAFQRLGSQVTQVEMAERLMGPE-DADTVELLTRRLTAEGIDIRLN 471
Query: 264 TKVLGVKKE-GSTI-----KVDVEAAKGGN----KEV-LDCDVVLISIGRRPYTKGLGLD 312
K L ++ G ++ VD E+ N K+V + D VLI++GR+P G GL+
Sbjct: 472 HKALRFEQHNGESVLIAEQTVDNESVDNQNADQSKDVEIPFDKVLIALGRQPNITGFGLE 531
Query: 313 KVGIALDDRGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPV--- 369
++G+ + + N QT P IYA GDV L H A + P
Sbjct: 532 ELGVQTNKT--VSTNELLQTNFPNIYACGDVAGPYQLTHVASHQAWYASVNALFDPFKTF 589
Query: 370 HFNYDAIPSVIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVL 429
+Y IP V YTSP+V VG TE+ KK + Y+V ++ RA + G VKVL
Sbjct: 590 RADYSVIPWVTYTSPQVANVGLTEQQAKKADKPYEVTEYDIGELDRAIADDSAYGRVKVL 649
Query: 430 SDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEA 480
+ D +LG +I+GP GEL+ E VLA +YG + H++PT AEA
Sbjct: 650 TKPGKDELLGVNIVGPQAGELLAEYVLAMKYGIGLNKILGTIHSYPTLAEA 700
>UniRef50_A6CLP9 Cluster: Pyruvate dehydrogenase E3; n=1; Bacillus
sp. SG-1|Rep: Pyruvate dehydrogenase E3 - Bacillus sp.
SG-1
Length = 476
Score = 251 bits (614), Expect = 4e-65
Identities = 146/465 (31%), Positives = 248/465 (53%), Gaps = 9/465 (1%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
+ +LV+IG GPGGY AAI+AAQLG+ V+ +EK+ LGG CLN GCIPSK + +
Sbjct: 9 ERELVIIGGGPGGYHAAIRAAQLGLSVLLIEKEE-LGGVCLNKGCIPSKVFTQLAKKHKE 67
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
H +++ G+++G V+ + K+ +YK++ + L G+ L + NKV ++KG + +A NK
Sbjct: 68 MAH-YQKMGLDSGSVSVNLTKLHDYKSSLIAQLKKGVDSLCKANKVEVIKGSASFLAENK 126
Query: 151 VEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
+ V + ++ +IA+G++ ++ +++ L +P++++V G+G
Sbjct: 127 IGVENGHQFTVYSFQSAIIATGAKRELPSFISGYSSRVLNEISIYELSELPEELVVYGSG 186
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
I LE S + LG VT L G + D + K L ++L K +K G VK
Sbjct: 187 YIELEAASSFAALGTKVT----LVLDGELPFDDSINKELTRVLKKMNVKLMTGFSPEEVK 242
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
+ + V + + + + ++ L + + GLG+D++ + L GRI ++
Sbjct: 243 ETHDGVSVTL-SKQDSDSVTIETSYFLAASKLKGNIDGLGVDRLKMNLTGDGRIEADSSC 301
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVG 390
T++ GIYA+GDV G LA KA +G V E G+P ++ +P + T P + +G
Sbjct: 302 LTSIQGIYAVGDVTTGSPLAVKAIKQGKVAAESAAGLPSAYDDVLLPVIAQTIPPIASIG 361
Query: 391 KTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGEL 450
TE++ E V +P N A+ GE EG +KV++D TD+ILG H+IG E+
Sbjct: 362 MTEKE-AAENHEVSVSIYPMGGNGFAQLIGEKEGLIKVVADLNTDLILGIHMIGNSAVEM 420
Query: 451 INEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
I+ + + E ED + + HP +E+L+EA + A GK ++
Sbjct: 421 ISGSAVGMEMAGRDEDFSYPYYPHPHTSESLQEA-MEALKGKAVH 464
>UniRef50_P75393 Cluster: Dihydrolipoyl dehydrogenase; n=6;
Mycoplasma|Rep: Dihydrolipoyl dehydrogenase - Mycoplasma
pneumoniae
Length = 457
Score = 251 bits (614), Expect = 4e-65
Identities = 164/458 (35%), Positives = 239/458 (52%), Gaps = 22/458 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL++IG+GP GYVAA A + +K + VEK+ GG CLNVGCIP+K LL + + +
Sbjct: 4 DLIIIGAGPAGYVAAEYAGKHKLKTLVVEKE-YFGGVCLNVGCIPTKTLLKRAKIVDYLR 62
Query: 93 HDFKQRGIE-TGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
H + GI G+V ++ +++E K V L GG+ + K V G ++ PN V
Sbjct: 63 HA-QDYGISINGQVALNWNQLLEQKGKVVSKLVGGVKAIIASAKAETVMGEAKVLDPNTV 121
Query: 152 EVHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQ--IITSTGALSLESVPKKMLVI 207
EV G+ T TK+I++A+GS PG + +I ST ALSLE VP+K++V+
Sbjct: 122 EVAGK----TYTTKSIVVATGSRPRYLTLPGFAEARQNGFVIDSTQALSLEGVPRKLVVV 177
Query: 208 GAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVL 267
G GVIG+E +Y LG++VT ++ + I + D EV+ + K+L + +K +V
Sbjct: 178 GGGVIGIEFAFLYASLGSEVTILQGVDRILEI-FDTEVSDLVAKLLQTKNVKIITNAQVT 236
Query: 268 GVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVN 327
+V ++ G + + D +L+SIGR P T+ L D + + D+R RI +N
Sbjct: 237 RANNN------EVFYSQNGQEGSVVGDRILVSIGRIPNTECL--DGLNLQRDERNRIVLN 288
Query: 328 NKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI--KGMPVHFNYDAIPSVIYTSPE 385
QT++P IY +GD MLAH A +G V I K PS IYT+PE
Sbjct: 289 QDLQTSIPNIYIVGDANAQLMLAHFAYQQGRYAVNHILNKKQVKPAQKLTCPSCIYTNPE 348
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGP 445
V VG TE +LKK+G Y +A + ET GFVK++ D T ILG II
Sbjct: 349 VASVGYTEMELKKQGIPYVKTNLVLAHCGKAIADNETNGFVKMMFDPQTGKILGCCIIAA 408
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
++I E LA G D+A HPT E + +
Sbjct: 409 TASDMIAELALAMGAGLTVFDIANSISPHPTINEMIAD 446
>UniRef50_A5IAB6 Cluster: Pyridine nucleotide-disulfide
oxidoreductase; n=4; Legionella pneumophila|Rep:
Pyridine nucleotide-disulfide oxidoreductase -
Legionella pneumophila (strain Corby)
Length = 464
Score = 250 bits (613), Expect = 5e-65
Identities = 148/457 (32%), Positives = 237/457 (51%), Gaps = 14/457 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D +++G G GG A+ A+ G K+ VE + +GGTC+NV CIP+K L+ ++ + H +
Sbjct: 6 DTIILGGGKGGKTLAMDLAKSGQKIAMVENNQ-IGGTCINVACIPTKTLVQSAKVAHYCR 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
K G+ T DFK + K V G+ F + ++L+ G G + P +E
Sbjct: 65 KA-KDYGLNTTLHPIDFKAIRARKDAVVNGMREANLKQFLDSGMDLMLGHGHFIGPKMIE 123
Query: 153 V------HGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLV 206
V +K + K I+ TP P D+ T+ ++ +SVP+ +L+
Sbjct: 124 VTLSSPRDNQKTLHITADKIIINTGALPYTP-PIAGLDKVNYFTNDSLMNTDSVPQHLLI 182
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
IG G IGLE +++R GA+VT IE + G D ++A+ + + LS +G++F + TK+
Sbjct: 183 IGGGYIGLEFAQMFRRFGAEVTVIEASSEFLGRE-DKDIAEQVFQTLSNEGIQFAVDTKI 241
Query: 267 LGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPV 326
+++E + +V +EA + G E++ VL+++GR T GL LDK G+ LD+RG I V
Sbjct: 242 NAIRQEQT--EVIIEANRQGQSEIIRGTAVLVAVGRIANTAGLHLDKTGVELDERGFIKV 299
Query: 327 NNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYD--AIPSVIYTSP 384
N +TT GI+A+GDV G H + D+ + ++ + IP ++ P
Sbjct: 300 NEFLETTAAGIWALGDVKGGAQFTHLSLDDYRLVKHNLQNPQKKLSSQNRLIPYTVFLDP 359
Query: 385 EVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 444
E+ +G TE + +GR K+ K P A RAKT GET G +K + D TD+ILG I
Sbjct: 360 ELARIGLTEAQARSQGRPIKIAKIPAAAIPRAKTQGETTGVLKAVIDAETDLILGVSIFC 419
Query: 445 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
GE++ LA E + + + AHPT E +
Sbjct: 420 AEAGEILGVIQLAMELRIPYQKLRDMMFAHPTLVEGI 456
>UniRef50_A3DNK1 Cluster: Dihydrolipoamide dehydrogenase; n=1;
Staphylothermus marinus F1|Rep: Dihydrolipoamide
dehydrogenase - Staphylothermus marinus (strain ATCC
43588 / DSM 3639 / F1)
Length = 451
Score = 250 bits (612), Expect = 6e-65
Identities = 148/464 (31%), Positives = 250/464 (53%), Gaps = 21/464 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+VV+G+G GGY AAI A+ G+KV +E+ LGG C N GC+PSKAL Y++A+
Sbjct: 3 DVVVVGAGVGGYPAAIYLARHGLKVAVIEEH-LLGGECTNYGCVPSKAL------YNIAE 55
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
F+ G D+ + + ++ VK GI L + V+++ + ++
Sbjct: 56 A-FRTIEKVGGNANIDWNNLSRWVSSVVKETRNGIEYLLESYGVDIINSKAVLKKDTAIK 114
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVI 212
+ G + ++ KNI++A G++ P P V FD K ++++ +E P+K+L+IG GVI
Sbjct: 115 I----GNDIISPKNIILALGTDPKPLPNVNFDGKYLLSNREVFYMEEKPEKILIIGGGVI 170
Query: 213 GLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKE 272
G+E + +LG DVT +E + +I +D +++ T+++ L ++ +K T V + E
Sbjct: 171 GVEAAYTFSQLGIDVTIVEAMPNILPF-LDKDISLTMKRFLREKNVKIYENTFVEKITIE 229
Query: 273 GSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQT 332
+ +K AK N +++ D +L++IGR+P T +GL+ V + +G I VN K+QT
Sbjct: 230 NNKVK-----AKLSNNNLIETDKILVAIGRKPKTTNIGLETVRVETTQKGFIKVNEKYQT 284
Query: 333 TVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKG-MPVHFNYDAIPSVIYTSPEVGWVGK 391
T P IYA+GDVI P+LAHKA E I I G +Y +P I++ E+ W+G
Sbjct: 285 TNPRIYAVGDVIGEPLLAHKAILESIAAARNILGEESFSLSYHLVPQTIFSGLEIAWIGY 344
Query: 392 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 451
TE +L+++G Y+ + P S + +VK+L D+ +V G ++ P E+I
Sbjct: 345 TERELREKGIKYRRIRMPVSHLSAVRIKDSKYSYVKILMDE-NNVPYGIFVVSPLASEVI 403
Query: 452 NEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
+ + E R+ + H T +E +RE + G+PI+
Sbjct: 404 SSFIPFIMNKIRLEKAWRIPYPHLTVSETVREIS-EYILGEPIH 446
>UniRef50_Q98PG2 Cluster: DIHYDROLIPOAMIDE DEHYDROGENASE; n=8;
Mycoplasma|Rep: DIHYDROLIPOAMIDE DEHYDROGENASE -
Mycoplasma pulmonis
Length = 627
Score = 249 bits (610), Expect = 1e-64
Identities = 162/479 (33%), Positives = 249/479 (51%), Gaps = 27/479 (5%)
Query: 20 RIATRQYATTHDA--DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIP 77
++A + Y +A D++VIG+GPGGY+AA +A + G+K + +EK GG CLNVGCIP
Sbjct: 147 KVAGKAYTGAVEAEYDVIVIGAGPGGYLAAEEAGKYGLKTLIIEKQ-YWGGVCLNVGCIP 205
Query: 78 SKALLHNSHLYHMAKHDFKQRGI--ETGEVTFDFKK----MMEYKANAVKGLTGGIAMLF 131
+KALLH + + +H + GI + + D +K + + K + V + GG+ L
Sbjct: 206 TKALLHATEELYNLEHSHEHNGIVADFKALKIDRQKTWINIQKNKKSVVDKIVGGVKFLM 265
Query: 132 QKNKVNLVKGVGTIVAPNKVEVHGEKGVETVNTKNILIASGS--EVTPFPGV--TFDEKQ 187
+ K ++G V +++EV+G+ KNI+IA+GS PG + ++
Sbjct: 266 KAAKATSIEGEAKFVGSHELEVNGK----VYRGKNIIIATGSLDRKLNLPGFEQAYKDEV 321
Query: 188 IITSTGALSLES-VPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSI-GGVGIDGEV 245
+++S ++L+S +P+ + +IGAGVIG+E V+ G VT I+ +I + E+
Sbjct: 322 VLSSDKLINLDSHLPETLGIIGAGVIGVEFAEVFAMAGTKVTIIQNTDAILANAPLAKEI 381
Query: 246 AKTLQKILSKQGMKFKLGTKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPY 305
L L K G++FK ++K +V GG +E + D +L ++GR P
Sbjct: 382 KTELTNHLKKYGVEFKFNASTTKIEKNQLFFEV------GGKEESMKFDKILAAVGRIPT 435
Query: 306 TKGLGLDKVGIALDDRGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIK 365
G +VGI + R I V++K T V +YAIGDV MLAH A I VE I
Sbjct: 436 PLNAG--EVGIEIGQRNEIIVDDKLMTNVENVYAIGDVTGKNMLAHVAYRHAIRVVESIV 493
Query: 366 GMPVHFNYDAIPSVIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGF 425
G + IP IYT PE+ +VG TE+ K+ G K+ F +A + E GF
Sbjct: 494 GEEEVYPKQEIPGCIYTKPEIAFVGLTEQQAKEAGYDVVTSKYSFSTLGKALASSEGNGF 553
Query: 426 VKVLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
V+++ DK ILG HIIG + I E VLA + + ++A H HPT E + EA
Sbjct: 554 VQLVVDKKYGRILGCHIIGKNSTDYIAEIVLAMDNEISVFEIAATIHPHPTYGEIVWEA 612
>UniRef50_A0B2P1 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=5; Burkholderia
cepacia complex|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Burkholderia
cenocepacia (strain HI2424)
Length = 454
Score = 244 bits (597), Expect = 4e-63
Identities = 147/451 (32%), Positives = 232/451 (51%), Gaps = 14/451 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
+ + +G G GG A+ A+ G +V +E+ +GG+C+NV CIPSK L+ N+ H +
Sbjct: 8 EYLFLGGGKGGKTLAMDMARQGRRVALIERG-MIGGSCINVACIPSKTLIQNARQVHGWR 66
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ D + E V G+ F+K+ ++L+ G G +AP +
Sbjct: 67 E-----AAGDASIMADMANVSENVRGVVDGMIKINRAAFEKSGLDLITGTGRFIAPRTIS 121
Query: 153 VHGEKGVETV-NTKNILIASGSEVTPFPGVT-FDEKQIITSTGALSLESVPKKMLVIGAG 210
V E G E + +N+ I +G+ V P V + Q +T AL L+ +P+ ++VIG G
Sbjct: 122 VRTEDGSEAIYEGENVYINTGT-VAQIPNVPGLRDAQPLTHVEALRLDELPEHIVVIGGG 180
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
IGLE+ ++RLG+ VT I + + D +V++ +Q+ L G+K +L +++ V+
Sbjct: 181 YIGLEMSQAFRRLGSAVTLIHDAPRVA-MREDEDVSREIQQALEADGIKLELQSRIANVR 239
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
+V +E A G V++ +L++ GR+P T +GLD G+ +D RG I V+ K
Sbjct: 240 GTSGQ-QVTIELADG---RVVEGSHLLVTTGRKPQTDAIGLDLAGVEVDGRGIIKVDEKL 295
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVG 390
TT P +AIG++ PM H + D+ V GI+G V IP ++ PE+G VG
Sbjct: 296 ATTAPRTWAIGEIAGTPMFTHASFDDYRVLKAGIEGRSVSTANRTIPYALFIDPELGRVG 355
Query: 391 KTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGEL 450
E D + EG +V K P A RA+TNG T GF+K L TD ILG ++G G G++
Sbjct: 356 LNEADARAEGILVRVAKLPMAAVPRARTNGNTRGFMKALIHPETDRILGFTMVGAGAGDV 415
Query: 451 INEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
+A G + V AHP +E L
Sbjct: 416 TTAVQMAMLGGLSYRAVRDSIIAHPLLSEGL 446
>UniRef50_Q1K375 Cluster: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase; n=1;
Desulfuromonas acetoxidans DSM 684|Rep: FAD-dependent
pyridine nucleotide-disulphide oxidoreductase -
Desulfuromonas acetoxidans DSM 684
Length = 454
Score = 242 bits (593), Expect = 1e-62
Identities = 153/460 (33%), Positives = 241/460 (52%), Gaps = 12/460 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPT-LGGTCLNVGCIPSKALLHNSHLYHMA 91
D+VV+G GP G ++A+K A G KV VE+ P LGGTCL+ GC+ +K++L + +Y
Sbjct: 6 DVVVLGGGPAGVMSALKLAMSGKKVCMVEQGPQRLGGTCLHEGCMATKSMLKTAEVYQTI 65
Query: 92 KHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
K ++ GIE D + K + +K L + + ++ +++ G G+ V+P ++
Sbjct: 66 KQA-EEYGIEATAAPLDLHCTVMRKNDHLKTLNNRLQQMALQSGLHIQPGHGSFVSPTRI 124
Query: 152 EVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGV 211
V G G + + I+IA+GS + D I+ S L +P+++L+IG G
Sbjct: 125 AVDGPDGHVELQAEKIVIATGSRPRELDEIPIDGALILNSNQMLQQTRLPERLLIIGGGA 184
Query: 212 IGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKK 271
IG E S++Q G+DVT IE + D + +TLQ L ++ ++ G ++ V K
Sbjct: 185 IGCEFASMFQAFGSDVTLIESAEHL-LPREDRDTGETLQTCLEQRDIRVLTGKTIVRVNK 243
Query: 272 EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQ 331
+ VE GN + L D +L+++GR+P T L L GI D I VN++ Q
Sbjct: 244 TDT----QVELVLQGNDQPLVADQMLVAVGRKPNTDWLDLAAAGIDCDGE-TICVNDQLQ 298
Query: 332 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGK 391
T+ P IYA GDVI+ MLAH A E + + G N IP V+Y+ P+V VG
Sbjct: 299 TSQPHIYAAGDVINTMMLAHSAMLESDIVAANLLGNNKTLNTATIPRVVYSFPQVAAVGL 358
Query: 392 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 451
TE +L ++ +Y+ PF +++A + EG +K+L D ++ I G IIG ELI
Sbjct: 359 TERELPED--SYRALFQPFGESAKALVDQRLEGHIKLLVDNDSNTICGATIIGEHATELI 416
Query: 452 NEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 491
+E L + + V HAHPT AE++ + LA + G
Sbjct: 417 HELALTISQDISLGVLKEVVHAHPTLAESIWD--LARHQG 454
>UniRef50_A5IXN5 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Mycoplasma agalactiae|Rep: Dihydrolipoyl dehydrogenase -
Mycoplasma agalactiae
Length = 541
Score = 239 bits (585), Expect = 1e-61
Identities = 160/472 (33%), Positives = 248/472 (52%), Gaps = 27/472 (5%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL+V+GSGPGGY+AA A + G+K + VEK+ GG CLN+GCIP+KA+L ++H
Sbjct: 70 DLIVVGSGPGGYLAAEMAGKAGLKTLIVEKE-FWGGVCLNIGCIPTKAMLRSTHALEEVI 128
Query: 93 HDFKQRGIETGE-VTFDFK----KMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVA 147
H K + E + D++ KM E KA V L+GG+ L + +KV +GV V
Sbjct: 129 HAAKFGVVANLEDLNIDYQQSWAKMHERKAKVVAKLSGGVKFLMKASKVQTEEGVAKFVG 188
Query: 148 PNKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEK-----QIITSTGALSLE-SVP 201
++EV+G+ KN+++A+GS + EK +++TS A++ + S+P
Sbjct: 189 AREIEVNGK----VYRGKNVILATGSHSNRMKFLEGFEKGYESGKLMTSREAINNDKSLP 244
Query: 202 KKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFK 261
M+++G GVIG+E +Y +G VT I+ + GID E+ KIL K K +
Sbjct: 245 ASMVIVGGGVIGVEFAQMYASMGTKVTIIQREDRLLP-GIDKEIVDEFAKIL-KTDSKIE 302
Query: 262 LGTKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDR 321
+ K E ++ K G +E + +V+LI+ GR P ++GL +VGI L R
Sbjct: 303 VIYGATSTKLEDDE---NLVYTKDGKEEKITAEVILIATGRVPASEGLA--EVGIELGAR 357
Query: 322 GRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVE---GIKGMPVHFNYDAIPS 378
+ V+ +T V G+YAIGDV + MLAH A + V I G+P +P+
Sbjct: 358 KEVKVDKFLRTNVKGVYAIGDVTNQNMLAHVAYIHAVTAVHHILDIYGIPYDPATKPVPA 417
Query: 379 VIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVIL 438
IYTSPE+ VG TE+ K+ G + V K+ F +A ET+G +K++ K ++
Sbjct: 418 CIYTSPEIATVGLTEDQAKEAGLDFIVSKYKFATLGKAIAAEETKGLIKLIVLKDGHIV- 476
Query: 439 GTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYS 490
G ++GP + + E +A E + + H HPT E + EA +A S
Sbjct: 477 GASLMGPNVTDYVAELAVAIEKRICVTALTHIIHPHPTFNEIIWEAARSALS 528
>UniRef50_Q090H7 Cluster: Soluble pyridine nucleotide
transhydrogenase (STH)(NAD(P)(+) transhydrogenase
[B-specific]); n=2; Cystobacterineae|Rep: Soluble
pyridine nucleotide transhydrogenase (STH)(NAD(P)(+)
transhydrogenase [B-specific]) - Stigmatella aurantiaca
DW4/3-1
Length = 491
Score = 238 bits (582), Expect = 3e-61
Identities = 156/459 (33%), Positives = 236/459 (51%), Gaps = 7/459 (1%)
Query: 28 TTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHL 87
T + DLVVIGSGP G A++AA++G +VV VEK+P LGGT N G +PSK L + L
Sbjct: 25 TMAEWDLVVIGSGPAGESGAVQAARMGKRVVVVEKEPVLGGTAANTGTLPSKTLRETA-L 83
Query: 88 YHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTG-GIAMLFQKNKVNLVKGVGTIV 146
Y G+ET + Y+ VK + I Q++ V +++GVG++
Sbjct: 84 YLSGYRARGLYGVETTLLHQATVSDFLYRERRVKDMERLRIGQNLQRHGVEVLQGVGSLE 143
Query: 147 APNKVEVHGEKGVETVNTKN-ILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKML 205
+ V V E E T + IL+A+GS P F + ++ S L L +P+ ++
Sbjct: 144 DAHTVVVRREGQPERRLTASFILVATGSSPYRPPLYPFGDDRVHDSDEVLELAELPRSIV 203
Query: 206 VIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTK 265
V+G GVIG E ++ LG VT ++ + +D E + L + +S G++ + G
Sbjct: 204 VVGGGVIGCEYACMFAALGIPVTLVDAKKELLPF-LDDEFSALLAQRMSALGIQLRFGHT 262
Query: 266 VLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIP 325
V + S + GG EVL+ VL++ GR T GLGL++VG+ L RG +
Sbjct: 263 VDALHMPESPPALLQLTLSGG--EVLEAHQVLVASGRTANTAGLGLEEVGVRLGTRGHVE 320
Query: 326 VNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPE 385
V +QT VP +YA+GD I P LA + ++ V V G P + +P IYT PE
Sbjct: 321 VGATYQTAVPHLYAVGDAIGFPALASTSMEQARVAVLHAFGAPQTLS-PILPYGIYTIPE 379
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGP 445
V G+TEE L+ +G Y G+ PF N R + GE G +K+L + + +LG H++G
Sbjct: 380 VSMAGETEESLRAKGIPYVAGRAPFSTNPRGQIIGEQHGLLKLLFHRESWKLLGVHVLGE 439
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
EL++ + A GA A+ C +PT +EA + A
Sbjct: 440 LATELVHVGLTAMVAGAGAQLFMETCFNYPTLSEAYKTA 478
>UniRef50_Q41EB7 Cluster: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase:Pyridine
nucleotide-disulphide oxidoreductase dimerisation
region; n=1; Exiguobacterium sibiricum 255-15|Rep:
FAD-dependent pyridine nucleotide-disulphide
oxidoreductase:Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Exiguobacterium
sibiricum 255-15
Length = 466
Score = 236 bits (578), Expect = 8e-61
Identities = 149/467 (31%), Positives = 231/467 (49%), Gaps = 19/467 (4%)
Query: 29 THDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLY 88
T + DLV++G GP GY AAI+A+QLG V +E+ +GG CLN GCIPSK + H + +
Sbjct: 7 TQERDLVILGGGPAGYTAAIRASQLGRTVTLIEQ-AQIGGLCLNKGCIPSKVVAHAAEVK 65
Query: 89 HMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAP 148
KH G T DF +++EY+ ++ L G+ L Q N + +V G + +A
Sbjct: 66 LQTKH-MTALGFSF-HPTHDFSQLVEYRERTIRQLRTGVEALCQANAIEVVHGTASFLAD 123
Query: 149 NKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
+++ V +T +++IA+GS + D ++ + L +P+++++IG
Sbjct: 124 DRIGVELGHQFDTYRFNDVVIATGSH-----SIKQDAPSVLNAEQLYQLTELPERLVIIG 178
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
I +E +Q LG VT I D + K L+++ KQ ++ GT
Sbjct: 179 QDYIAIEAAMSFQALGTSVTLIA-----DAFDFDPSLDKELRRLFKKQKIQLVTGTVTAI 233
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
+E T+ V K G + + S+ R P+T LGL+++G+ L + G IPV+
Sbjct: 234 EAQEDVTVTV----VKQGQETTWSAPFLFHSLPRVPHTLELGLERIGVTLAEDGTIPVDP 289
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGW 388
QT P IYAIGDV GP +A +A E E + G P++I + P +
Sbjct: 290 FGQTNRPHIYAIGDVTPGPAIATRAIHEAKRTAEHLSGQSADTTVPYYPTIIRSLPPIVS 349
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
+G TE+ G +++ +F AN G + GF+KV+SD TT +ILG H+IG G
Sbjct: 350 IGLTEQTATDAGHSFRTAQFALNANGATTIEGGS-GFIKVISDATTSLILGIHMIGEGAI 408
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
EL E A EDV HP+ EA EA + A G+ I+
Sbjct: 409 ELAGVFAQTLELHAKEEDVRFPVMPHPSRNEAFTEA-IEALLGQAIH 454
>UniRef50_A7HGF8 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=2;
Anaeromyxobacter|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Anaeromyxobacter
sp. Fw109-5
Length = 456
Score = 235 bits (575), Expect = 2e-60
Identities = 150/462 (32%), Positives = 231/462 (50%), Gaps = 19/462 (4%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
D D +VIGSG G A + A+ G KV+ E+ LGGTC+N GC P+K L+ ++ H+
Sbjct: 2 DLDAIVIGSGQAGVPLATRLAKHGRKVLLAER-ADLGGTCINTGCTPTKTLVASARAAHV 60
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQK--NKVNLVKGVGTIVAP 148
A+ ++ G+ V DF ++ K V+ GIA + LV+G +V
Sbjct: 61 AR-SARRLGVRVDSVAVDFPAVIARKDAIVRRWQEGIARRLADAGENLRLVRGEARLVGE 119
Query: 149 NKVEVHGEKG-VETVNTKNILIASGSEVTP-FPGVTFDEKQIITSTGALSLESVPKKMLV 206
VE+ GE+ TV IL G + P PG+ + + + L +P ++V
Sbjct: 120 RTVEIAGERHRAATV----ILNVGGRPIEPPIPGL--GGVPWLDNRRVMELPELPSHLVV 173
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
+G G IG EL Y+R GADVT IE + G G D EV++ ++ + +G+ L +
Sbjct: 174 VGGGYIGCELAQAYRRFGADVTVIEPGKHLLGNG-DPEVSEAIEGVFRDEGVALLLDARA 232
Query: 267 LGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPV 326
V ++G + V + + + +L++ GRRP T LG + G+ LD RG + V
Sbjct: 233 EAVSRDGGRLTVRLSTGR-----TVTGSHLLVATGRRPNTDDLGAEAAGVKLDGRGFVEV 287
Query: 327 NNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDA-IPSVIYTSPE 385
++ ++++ PGIYA+GD GP H A D+ + + + G P D +P YT P+
Sbjct: 288 DDHYRSSAPGIYAVGDCAGGPQFTHAAWDDHRLLFDVLMGKPGRGRKDRLVPYTAYTDPQ 347
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGP 445
V VG TE + +G Y+V PF +RA E G +K+L D T+ ILG I+G
Sbjct: 348 VAGVGLTERAARDQGVEYEVATLPFENIARAIETDEKAGLLKILVDPATERILGASIVGA 407
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 487
GELI+ + GA A V + HP+ AE L+ +A
Sbjct: 408 EAGELIHVFAALMQAGATARAVVDMEAVHPSLAEGLQSVVMA 449
>UniRef50_Q311A9 Cluster: 2-oxoglutarate dehydrogenase, E3
component, lipoamide dehydrogenase; n=3;
Desulfovibrio|Rep: 2-oxoglutarate dehydrogenase, E3
component, lipoamide dehydrogenase - Desulfovibrio
desulfuricans (strain G20)
Length = 460
Score = 234 bits (572), Expect = 5e-60
Identities = 152/466 (32%), Positives = 236/466 (50%), Gaps = 18/466 (3%)
Query: 29 THDA-DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHL 87
TH+ DLV+IG+GPGG AA+ AA GM+ VEK GGTCLN GCIP+K LL +
Sbjct: 2 THEQYDLVIIGAGPGGSRAALDAAAAGMRTALVEKADA-GGTCLNWGCIPTKFLLGGTAA 60
Query: 88 YHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVA 147
+ + K + G+V + + K +KG + + VN + G +
Sbjct: 61 VPLLQIQKKYKAAG-GDVHLSLAALHQRKDRFIKGTRQNLVKQLTQAGVNFITGAASFAG 119
Query: 148 PNKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVI 207
P V V E G + +N+++A+GSE FPG+ D ++ S+ L LE+ P+ ++++
Sbjct: 120 PRTVVVEKEDGSSLLEFENLILAAGSEPASFPGLIPDGNCVLHSSHILQLETPPQSLIIV 179
Query: 208 GAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV- 266
G G IGLE+G ++ R G +T +E L + DG++A L K L ++G G +V
Sbjct: 180 GGGAIGLEMGDLFARFGTQITIVEALPHLVPAE-DGDIADALTKALKREGWTVHTGRRVR 238
Query: 267 -LGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIP 325
L +EG+ + + A + D L++ GR P T L +K GI D RG I
Sbjct: 239 SLVTDEEGALLTFEDGTA-------IRADKALMAAGRSPATAALHPEKAGIMTDGRGWIS 291
Query: 326 VNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGM-PVHFNYDAIPSVIYTSP 384
+N F IYA+GDV +LAH AE + V ++G+ + +PS +Y
Sbjct: 292 TDN-FLQAAENIYAVGDVNGRTLLAHAAEHQARYVVSRLRGLTAAEYPAPVMPSCVYGHM 350
Query: 385 EVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVL--SDKTTDVILGTHI 442
EV G T ++L +G + V + P +N+ A++ G T+GFVK + + T + G
Sbjct: 351 EVMRTGATAKELTAQGISVSVSRAPLASNAIAQSCGATQGFVKAVWAAGNGTPELRGIAA 410
Query: 443 IGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAA 488
G G L+ A + + E++ + +AHPT EAL EA L+A
Sbjct: 411 TGHGVSHLVGLATVMVQQRWRRENIHDIIYAHPTLDEAL-EAALSA 455
>UniRef50_P30341 Cluster: Mercuric reductase (EC 1.16.1.1) (Hg(II)
reductase); n=27; Bacteria|Rep: Mercuric reductase (EC
1.16.1.1) (Hg(II) reductase) - Streptomyces lividans
Length = 474
Score = 233 bits (571), Expect = 6e-60
Identities = 149/455 (32%), Positives = 231/455 (50%), Gaps = 8/455 (1%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL +IGSG G + AAI A G VV VE+ T GGTC+NVGC+PSKALL + H A+
Sbjct: 9 DLAIIGSGAGAFAAAIAARNKGRSVVMVERGTT-GGTCVNVGCVPSKALLAAAEARHGAQ 67
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGG-IAMLFQKNKVNLVKGVGTIVAPNKV 151
+ GI+ E DF ++ K V L L + +V G T +
Sbjct: 68 AASRFPGIQATEPALDFPALISGKDTLVGQLRAEKYTDLAAEYGWQIVHGTATFADGPML 127
Query: 152 EVH-GEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
EV + G TV + LIA+GS T D+ +TST A+ L+ +P+ +L++G G
Sbjct: 128 EVALNDGGTATVEAAHYLIATGSAPTAPHIDGLDQVDYLTSTTAMELQQLPEHLLILGGG 187
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
+GLE ++ RLG+ VT + S + E++ ++ I ++G+ T++ V+
Sbjct: 188 YVGLEQAQLFARLGSRVTLA--VRSRLASREEPEISAGIENIFREEGITVHTRTQLRAVR 245
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
++G I + G + + +LI+ GRR T GLGL++VG+ +RG + V+
Sbjct: 246 RDGEGILATLTGPDGDQQ--VRASHLLIATGRRSVTNGLGLERVGVKTGERGEVVVDEYL 303
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEG-IVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWV 389
+T P I+A GDV P + A G +V + G +Y A+P V +TSP + V
Sbjct: 304 RTDNPRIWAAGDVTCHPDFVYVAAAHGTLVADNALDGAERTLDYTALPKVTFTSPAIASV 363
Query: 390 GKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGE 449
G TE L + G A++ RA N +T G VK+++++ T +L H++ G G+
Sbjct: 364 GLTEAQLTEAGIAHQTRTLSLENVPRALVNRDTRGLVKLIAERGTGKLLAAHVLAEGAGD 423
Query: 450 LINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
+I A A G + +AR H + T AEAL+ A
Sbjct: 424 VITAATYAITAGLTVDQLARTWHPYLTMAEALKLA 458
>UniRef50_Q74A03 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Geobacter|Rep: Dihydrolipoyl dehydrogenase - Geobacter
sulfurreducens
Length = 452
Score = 232 bits (567), Expect = 2e-59
Identities = 145/447 (32%), Positives = 226/447 (50%), Gaps = 15/447 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKD-PTLGGTCLNVGCIPSKALLHNSHLYHMA 91
D+VVIG GPGG A + Q G V ++++ + GG CLN GC+P+K++L + +Y A
Sbjct: 5 DVVVIGGGPGGMTAGMMLKQAGKSVAIIQENHDSFGGVCLNRGCMPTKSMLKAAKVYRDA 64
Query: 92 KHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
++ K G++ D ++ + L + ++ + +G G+ ++ +++
Sbjct: 65 QNSEKY-GLDLSVNPVDLTRLRAVADADLNMLRHMVQGKLTDARIAVFRGKGSFLSEHEL 123
Query: 152 EV-HGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
++ + E + + I+IA+GS P FD I++S L +P K+L+IG G
Sbjct: 124 QICQADGSSEQIRGEKIIIATGSVPAELPCAPFDGHSILSSDQILKNTDLPHKLLIIGGG 183
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
IG E ++Y G+ VT +E + S+ D E KTLQ +QG+ K G + +
Sbjct: 184 AIGCEFATLYNTFGSRVTLVEAMDSL-LPREDKEAGKTLQSTFEQQGITVKTGAAIKSIS 242
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
E T+ V + G+ + D VL+ IGR GL LD G+A ++G + VN
Sbjct: 243 VEAGTVHVHYD----GSCATEEFDKVLVGIGRTANIAGLNLDAAGVA-TEQGAVKVNEMM 297
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEG-IKGMPVHFNYDAIPSVIYTSPEVGWV 389
QTTVP IYA+GDVI G LAH AE EG + + I+G ++ A+P V++ PEV V
Sbjct: 298 QTTVPHIYALGDVIGGMTLAHAAEKEGYLLAQNLIQGTRHPLDHRAVPRVVFCHPEVAAV 357
Query: 390 GKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGE 449
G E + G K P N RA + FVK+ ++ T I G IIG G E
Sbjct: 358 GTHE---ARAG--IKAFTMPQAPNGRAVVDKVAPAFVKLFIEEDTSQIAGAIIIGEGATE 412
Query: 450 LINEAVLAQEYGAAAEDVARVCHAHPT 476
+I+E +A E E + + HAHPT
Sbjct: 413 MIHEMAVAVENRLTLEQIGKTVHAHPT 439
>UniRef50_Q6MDA0 Cluster: Probable soluble pyridine nucleotide
transhydrogenase; n=1; Candidatus Protochlamydia
amoebophila UWE25|Rep: Probable soluble pyridine
nucleotide transhydrogenase - Protochlamydia amoebophila
(strain UWE25)
Length = 465
Score = 230 bits (562), Expect = 7e-59
Identities = 155/463 (33%), Positives = 233/463 (50%), Gaps = 23/463 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKAL------LHNSH 86
D+V+IGSGP G AAI+AA+LG V+ +EK+P LGG CL G IPSK L H
Sbjct: 7 DIVIIGSGPAGQKAAIQAAKLGKNVIVIEKEPELGGACLYSGTIPSKTFREAVVDLTRFH 66
Query: 87 LYHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIV 146
H A D+ + E+ ++ + N I F+KN + +++G
Sbjct: 67 DRHFAGKDYILPNVTIDELNVRLHTVINEERNI-------ITRQFKKNSIRVIQGSARFE 119
Query: 147 APNK-VEVHGEKGVE-TVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKM 204
+ + V + ++ + + +IA+GS P V FD++ I+ ST L + VPK M
Sbjct: 120 NQHTLIVVDNDFRLKYQIKATSFIIATGSNPRNPPDVPFDQQVILDSTTLLGIGRVPKSM 179
Query: 205 LVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGT 264
+V+G G+IG E S + LG +VT I+ + + +D E+ LQ L+ G+KF
Sbjct: 180 IVLGGGIIGSEYASFFAALGTEVTVIDRKDHMLPL-LDAEIGIHLQTALTDIGLKF---- 234
Query: 265 KVLGVKKEGSTIKVDVEA-AKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGR 323
LG K+ +V+ A K + L+ DV+L ++GR + L ++ GI +D +G
Sbjct: 235 --LGKKEPVEISRVEDHAYVKFKDGSSLEADVLLYALGRLANIEALHVENTGIIVDAKGY 292
Query: 324 IPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTS 383
IPVN FQT +P IYA+GDVI GP LA + ++G + G+ H P IYT
Sbjct: 293 IPVNALFQTVIPHIYAVGDVIGGPCLASTSMEQGRLAARHACGVQTHHFPTFYPVGIYTI 352
Query: 384 PEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHII 443
PE+ G TEE+LK G Y+VG+ + +R+ G G K+L T ILG H+I
Sbjct: 353 PEISSCGYTEEELKAWGFHYEVGRAHYYEIARSHIAGSNTGLFKILFHAETLEILGVHVI 412
Query: 444 GPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANL 486
G E+I+ + + A + +PT AE R A L
Sbjct: 413 GRNATEVIHIGQMGISFRAHIDYFIDHVFNYPTYAEGYRVAAL 455
>UniRef50_Q0SUA0 Cluster: Pyridine nucleotide-disulphide
oxidoreductase; n=9; Bacteria|Rep: Pyridine
nucleotide-disulphide oxidoreductase - Clostridium
perfringens (strain SM101 / Type A)
Length = 457
Score = 229 bits (561), Expect = 1e-58
Identities = 144/458 (31%), Positives = 240/458 (52%), Gaps = 17/458 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEK-DPTLGGTCLNVGCIPSKALLHNSHL-YHM 90
+ ++IG G GG A +LG KV +EK D GGTC+NVGCIP+K L++ S + +
Sbjct: 5 EYIIIGFGKGGKTLAGYLGKLGKKVAIIEKSDKMYGGTCINVGCIPTKTLVNKSKVSLYK 64
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTG-GIAMLFQKNKVNLVKGVGTIVAPN 149
+ F+++ E ++K +E K ++ L ML V++ G + ++
Sbjct: 65 GLNTFEEKARE-------YRKSIEEKNALIEALRDKNYNMLNNNENVDVFNGTASFISNT 117
Query: 150 KVEVHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVI 207
++ ++ EK + + I I +G+ + G+ K I ST + L+ +PK ++++
Sbjct: 118 EILINSEKEDIILEGEKIFINTGATTIIPNIQGIKSSSK-IYNSTTIMELKELPKHLVIV 176
Query: 208 GAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVL 267
G G IGLE S+Y G+ VT IE I G D +++K++++IL K+G++F LG+KV
Sbjct: 177 GGGYIGLEFASIYASFGSKVTVIEAFDRIAGRE-DEDISKSIKEILEKKGIEFLLGSKVK 235
Query: 268 GVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVN 327
++ ++V E + G ++ D VLI+IGR+P T+ L L+ G+ + +RG I VN
Sbjct: 236 SFEEIHGEVEVSYENSLGELNKITG-DAVLIAIGRKPNTEELNLEAAGVKVTERGAIEVN 294
Query: 328 NKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDA--IPSVIYTSPE 385
NK +T +P I+AIGDV GP + + D+ + + + G D IP ++ P
Sbjct: 295 NKLKTNIPNIWAIGDVNGGPQFTYISLDDFRIIKDNLFGEGKRSTDDRKFIPYSVFIEPN 354
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGP 445
+ VG +E++ ++G K K RAK GETEG +K + D T+ ILG ++
Sbjct: 355 LSRVGLSEKEALEKGFEIKTAKLDVNTIPRAKVIGETEGIMKAIVDVKTNKILGCTLLCA 414
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
E+IN LA + + HPT +EAL +
Sbjct: 415 ESAEIINIVTLAMKADEDYTFLRDNIFTHPTMSEALND 452
>UniRef50_P35484 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Acholeplasmataceae|Rep: Dihydrolipoyl dehydrogenase -
Acholeplasma laidlawii
Length = 336
Score = 229 bits (561), Expect = 1e-58
Identities = 131/336 (38%), Positives = 200/336 (59%), Gaps = 19/336 (5%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
+++++G GPGGYVAAIKAAQ G KV VEK+ +GG CLN GCIP+K L ++ +++ K
Sbjct: 6 EIIIVGGGPGGYVAAIKAAQYGAKVALVEKE-VVGGICLNHGCIPTKTFLKSAKVFNTVK 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+GEV FD+ K++ K VK LT G+A L +KN V++ G G I + N+V
Sbjct: 65 KSMDFGVSTSGEVGFDWSKIVSRKDGVVKQLTNGVAFLLKKNGVDVYNGFGDIKSANEVV 124
Query: 153 VHGEKGVETVNTKNILIASGSE--VTPFPGV--TFDEKQIITSTGALSLESVPKKMLVIG 208
V+G E++ TKN++IA+GS V P PGV +++ ++TS L++++ PK ++++G
Sbjct: 125 VNG----ESLKTKNVIIATGSSAVVPPIPGVKEAYEKGIVVTSRELLNVKNYPKSIVIVG 180
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
GVIG+E +V+ G+ VT IE + I +D ++ K L + G++ +V
Sbjct: 181 GGVIGVEFATVFNSFGSKVTIIEMMDGILPT-MDDDIRVAYAKTLKRDGIEILTKAEVKK 239
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
V T +D G + ++ D++L+S+G R +K GL+ +G+ + DR I N
Sbjct: 240 VDDHKVTYSLD------GKETTIEGDLILMSVGTRANSK--GLEHLGLEM-DRANIKTNE 290
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI 364
QT VPG+YAIGDV MLAH AE EGI V+ I
Sbjct: 291 YLQTNVPGVYAIGDVNGKFMLAHVAEHEGITAVQHI 326
>UniRef50_A3I4Y3 Cluster: Acetoin dehydrogenase, E3 component,
dihydrolipoamide dehydrogenase; n=1; Bacillus sp.
B14905|Rep: Acetoin dehydrogenase, E3 component,
dihydrolipoamide dehydrogenase - Bacillus sp. B14905
Length = 461
Score = 229 bits (560), Expect = 1e-58
Identities = 159/466 (34%), Positives = 240/466 (51%), Gaps = 29/466 (6%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+ +IG+GPGGYVAAI AA+ G +V +E+D LGG C NVGCIPSK LL +S L A
Sbjct: 21 DIAIIGAGPGGYVAAIHAAKNGKRVALIERDK-LGGACYNVGCIPSKILLEHSKLVQ-AI 78
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ GIET V +F ++M+ K ++ L I N + L +G T+ +
Sbjct: 79 NQGNNWGIETDNVRINFPRLMQRKDTIIQELLTNIEHYIINNDITLYRGEATLTKDLLIT 138
Query: 153 VHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
V G ET+ +I++A+GS V PF G+ + T+ +L+ +P ++ +IG G
Sbjct: 139 V----GNETLTATDIILATGSHPFVPPFQGL--ETATYYTTDTFFNLKELPAQLTIIGGG 192
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
VI +E+ LG VT + I + E +++ + K G++ L T K
Sbjct: 193 VIAVEMAFSLAPLGTKVTMLNHSEDILQTE-EPESRPLIREKMKKLGIE--LVTDFEFEK 249
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
EG TI K + +L + GRRP T+ +G+A + I VN+
Sbjct: 250 FEGHTIHT--------TKGTYTYENLLFATGRRPNTEIA--QHLGLAFEGL-LIAVNDHL 298
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKG-MPVHFNYDAIPSVIYTSPEVGWV 389
QT+ P +YAIGD++ G LAH A EGI V+ I G P + +IP +YT PE+
Sbjct: 299 QTSQPHLYAIGDLVGGYQLAHSASAEGIYAVDYIVGNQPASIDQASIPRCVYTHPEIATF 358
Query: 390 GKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGE 449
G EE +K Y + K P N + G TEGFVK++++K + ILG ++G G E
Sbjct: 359 GLLEEQVKVP---YTMTKMPLKTNPKGLMEGNTEGFVKLITEKGSGQILGACVVGNGATE 415
Query: 450 LINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPIN 495
++N + A+ G A +A++ HPT E + +A A + GK I+
Sbjct: 416 MLNAILAAKNAGGTALSLAQMIFPHPTVCEHIGDAAKAVF-GKAIH 460
>UniRef50_Q2S6F1 Cluster: Mercuric reductase; n=3; Bacteria|Rep:
Mercuric reductase - Salinibacter ruber (strain DSM
13855)
Length = 525
Score = 228 bits (558), Expect = 2e-58
Identities = 147/456 (32%), Positives = 238/456 (52%), Gaps = 12/456 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL+VIG+G GG A A+ G V +E+ +GGTC+N GC P+K ++ ++ + H+A+
Sbjct: 56 DLIVIGAGQGGGPLAGAVAEAGHDVALLERRH-VGGTCVNRGCTPTKTMIASARVAHLAR 114
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGL-TGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
G+ETG+V+ D + + + K + V +G + + +K+ ++L++G G V PN V
Sbjct: 115 RA-GDYGVETGDVSVDLETVRQRKRDIVGMFRSGSRSSIEEKDTLDLIEGDGRFVDPNTV 173
Query: 152 EV--HGEK---GVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLV 206
EV +G+ G + I+I +G+ P D +TST + L +VP +L+
Sbjct: 174 EVTLNGDANDGGPRALTADRIVINTGTRPAIPPIDGLDAVDFLTSTSIMELGAVPGHLLI 233
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
+G G IGLE G +++R GA+VT I+ + G D +VA L+ IL + G++ T +
Sbjct: 234 LGGGYIGLEFGQMFRRFGAEVTIIDRGEHVLGRE-DADVAGALEDILREDGIRLLNETSM 292
Query: 267 LGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPV 326
V++ G TI +E + + D +L++ GRRP T L G+A ++G + V
Sbjct: 293 TAVEEAGGTITAHLEGDDAPAR--ITGDELLVAAGRRPNTDALNPGAAGVATTEQGYVQV 350
Query: 327 NNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVE-GIKGMPVHFNYDAIPSVIYTSPE 385
+ + TT GIYAIGDV GP H + D+ V + + G I ++T P+
Sbjct: 351 DARLATTADGIYAIGDVTGGPAFTHVSYDDYRVLQDHWLHGGDRTTEDRLIAYTLFTDPQ 410
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGP 445
+G VG TEE + G V + P +RA ET G +K + D TT+ +LG ++G
Sbjct: 411 LGRVGLTEEQARSRGLDVTVAQMPMTRVARALEVDETRGLMKAVIDSTTNRLLGAAVLGI 470
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
GGE+++ A + AHPT AE+L
Sbjct: 471 EGGEVMSVLQTAMMGDLPVGRLRAAPFAHPTLAESL 506
>UniRef50_A3XLG1 Cluster: Dihydrolipoamide dehydrogenase; n=3;
Bacteria|Rep: Dihydrolipoamide dehydrogenase -
Leeuwenhoekiella blandensis MED217
Length = 577
Score = 228 bits (558), Expect = 2e-58
Identities = 139/457 (30%), Positives = 226/457 (49%), Gaps = 12/457 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHL-YHMA 91
DL+VIG G + AAIKA LG+ + V GGTC+NVGC+PSK L+ + YH
Sbjct: 112 DLIVIGGGSAAFSAAIKAESLGLTTLMVNGGLDFGGTCVNVGCVPSKNLIRAAETAYHTT 171
Query: 92 KHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNL--VKGVGTIVAPN 149
+F GI+ DF ++++ K V L M + NL +KG V N
Sbjct: 172 HSNFA--GIKPKGADIDFAQIIKDKKALVAALQQQKYMDVVSDFENLTMLKGWAEFVNNN 229
Query: 150 KVEVHGEKGVETVNTKNILIASGSEVTPFPGVT-FDEKQIITSTGALSLESVPKKMLVIG 208
+ V G+ +T N++IA+G+ T P + +E +T+ LE PK + ++G
Sbjct: 230 TIIVDGK---DTYTATNVVIATGA-TTNIPNIEGLNEVGYLTNVSLFDLEEKPKSLTIMG 285
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
AG IGLE+ Y RLG V IEF T ++ L + + +G++ +
Sbjct: 286 AGYIGLEMAMAYNRLGVKVRIIEF-TDRPLRSQTEDITDVLVEQMKSEGIEILPNFRAFK 344
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
+KEG+ + G ++++ ++++ G P T LGL K+ + L +RG I VN
Sbjct: 345 FEKEGNDTIIHCNCPDGSTTQIVEKGHIVVATGTTPNTSKLGLKKIDLKLSERGHIVVNE 404
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH-FNYDAIPSVIYTSPEVG 387
K +T + IYA GDV + P + A EG V + +Y ++P V++T P++
Sbjct: 405 KMETNISNIYAAGDVTNTPPFVYTAATEGSTAVNNAFSLSKQSVDYASLPWVVFTDPQIA 464
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
G E + + G ++V K RA +T GF+K++ + TD ++G +I P G
Sbjct: 465 GAGMDEIEAESRGIPFEVSKLDLTHVPRALAAQDTRGFIKLIRNTETDKLIGARVIAPEG 524
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
GELI + +A ++G +D+A + + T E ++ A
Sbjct: 525 GELIQQLSMAIKFGITVKDLAESFYPYLTLGEGIKLA 561
>UniRef50_A4YI59 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=2;
Sulfolobaceae|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Metallosphaera
sedula DSM 5348
Length = 449
Score = 228 bits (557), Expect = 3e-58
Identities = 143/454 (31%), Positives = 234/454 (51%), Gaps = 16/454 (3%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
D D++VIG G G AA++A++LG V VE+D +GG C+N CIPSK L+ +
Sbjct: 2 DFDVIVIGGGVAGVSAALRASELGKSVALVERDQ-VGGECINRACIPSKTLIDAVKTVNR 60
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
T D+ K+ E KA + + + V ++KG I A +
Sbjct: 61 VSSS----PWIVSSATLDYAKLNENKARIITAIKDRMEHNLNARNVKVIKGNAKIKAQGE 116
Query: 151 VEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
VEV G T+ ++++++GS P + + ++ A++L+ + +++++G G
Sbjct: 117 VEVDGR----TITGDHLVLSTGSVPLSLPDFPLNGRNVLDPWTAMNLKEIKNRIVIVGGG 172
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
V G+EL ++++ L +VT +E + + G D ++A +K L ++G++ L K V
Sbjct: 173 VAGVELATLFRALNKEVTILELMPQLLP-GFDRDLASATKKRLEEKGIRIYLNAKSKIVN 231
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
EG T+K V E ++ D+ +++IGR+ T+ L L ++G+ D RG + V+ +
Sbjct: 232 SEG-TVKFSVNLPNAS--EEVEGDLAVVTIGRKASTENLNLKEIGVETDQRGYVKVDERG 288
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVG 390
+TT P ++A GDV P+ A KA +GIV + I G IPS I+ E+G VG
Sbjct: 289 RTTNPKVFAAGDVAGVPLSATKAWRQGIVAGDNIGGKESKMP-KYIPSSIFADMEIGTVG 347
Query: 391 KTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGEL 450
KT +DLKK G + RA T ET+GF+K++ + I G H+IG G E+
Sbjct: 348 KTLDDLKKAGIEAREIMVEMRDIPRAWTLNETDGFLKLV--VAGNKIEGAHMIGEGATEV 405
Query: 451 INEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
IN LA E G + V +HPT +E + EA
Sbjct: 406 INTMALAMELGITTTQLYSVTFSHPTVSEVIGEA 439
>UniRef50_Q0W154 Cluster: Pyruvate dehydrogenase complex E3,
dihydrolipoamide dehydrogenase; n=1; uncultured
methanogenic archaeon RC-I|Rep: Pyruvate dehydrogenase
complex E3, dihydrolipoamide dehydrogenase - Uncultured
methanogenic archaeon RC-I
Length = 467
Score = 227 bits (556), Expect = 4e-58
Identities = 144/453 (31%), Positives = 225/453 (49%), Gaps = 11/453 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D++VIG+GP GY AAI+ Q+GM V V P +GG CLN GCIP K ++ L
Sbjct: 11 DVLVIGAGPAGYTAAIRLGQMGMDVTLV--GPEIGGICLNHGCIPVKGIVRTLDLVADVT 68
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ RGI+ V D K+ + A ++ L GI L + V L +G + +
Sbjct: 69 AA-EARGIKAHGVEVDLNKVQAWNAQVIRKLQAGIRSLLNASGVQLFEGTCSFTSSTTAV 127
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVI 212
V + + + +IA+G G+ D ++II L VP +++G G+
Sbjct: 128 VRIHGSTQHIRFRKAVIATGMHYIVPEGIRPDGRRIIFPHAVAHLHKVPGTAVILGGGID 187
Query: 213 GLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKE 272
G + S+ ++G VT + + ++ ID +V + K L+ G++ V E
Sbjct: 188 GATMASLLAKMGTRVT-LAYKSASLVPAIDDDVLQPAMKSLADLGVQ-TFPQASWEVHSE 245
Query: 273 GSTIKVDVEAAKGGNKEVLDC-DVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQ 331
G + + + GN+ D++LI + + L LD+ + L D+G + V+++++
Sbjct: 246 GGEVVI-----RSGNETTTRTPDLILICSPTKANVQNLSLDRTKVRLTDKGFVEVDDRYR 300
Query: 332 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGK 391
T P IYAIGDV+ G A A +G+ I G P +Y A+ I ++ G
Sbjct: 301 TADPSIYAIGDVLGGRRNASVAFRDGLSVANIIAGKPGLPDYQAMTLTIEAGLDIASAGM 360
Query: 392 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 451
E++ KK G V + P+ AN A T G+ +GF+KV+++K T ILGT I+GP G+LI
Sbjct: 361 GEKEAKKAGIDVTVSRSPYSANGGAATYGKQDGFIKVVAEKQTGRILGTQIVGPRAGDLI 420
Query: 452 NEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
EA+LA E GA EDVA H HP E +A
Sbjct: 421 GEALLAIEMGARLEDVALTLHPHPELNEIFADA 453
>UniRef50_Q3VU31 Cluster: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase:Pyridine
nucleotide-disulphide oxidoreductase dimerisation
region; n=2; Chlorobiaceae|Rep: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase:Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
- Prosthecochloris aestuarii DSM 271
Length = 495
Score = 227 bits (555), Expect = 5e-58
Identities = 152/462 (32%), Positives = 231/462 (50%), Gaps = 13/462 (2%)
Query: 30 HDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYH 89
+D D+ VIG G G AA AA LG K VE + LGG C GCIPSK LL + H
Sbjct: 3 YDYDVTVIGGGAAGLTAAGVAASLGAKTALVE-EKKLGGDCTWYGCIPSKTLLKAAKAAH 61
Query: 90 MAKHDFKQRGIET-GEVTFDFKKMMEYKANAVKGL--TGGIAMLFQKNKVNLVKGVGTIV 146
+H + GIET GE++ +F+ +M + + +++K V ++ G V
Sbjct: 62 TIRHAARF-GIETHGEISINFETVMRRVHEVQQQIYQEADAPEIYEKMGVTVLYGKAAFV 120
Query: 147 APNKVEVH-GEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKK 203
+ + + G+ G+ T+ +KN++IA+GS P PG+ ++ +T+ SL+ P++
Sbjct: 121 DEHTITIETGQSGISTLQSKNVIIATGSRPITPPIPGL--EKVSYVTNEQLFSLKKQPRQ 178
Query: 204 MLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLG 263
+L++GAG IG+E+G + RLG+ V + I E+ LQK+L ++GM F L
Sbjct: 179 LLILGAGPIGIEMGQAFCRLGSKVHVFDAEEHILPKD-HPELTAILQKVLEQEGMTFHLQ 237
Query: 264 TKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGR 323
+V V + I V E G L D +L++ GR T+ L L+ G+ RG
Sbjct: 238 YRVTQVDEMDGIITVTAEEETTGRTIQLTGDALLVAAGRAANTENLNLEAAGVTTHKRG- 296
Query: 324 IPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEG-IVCVEGIKGMPVHFNYDAIPSVIYT 382
I VN QT+ IYA GDV G H AE I + +P+ + IP YT
Sbjct: 297 ITVNQYCQTSRSHIYACGDVAGGMQFTHIAEHMAKIAAGTMLTHLPLQTDDRHIPWCSYT 356
Query: 383 SPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHI 442
PE+ VG+TE +L ++V +FPF RA T TEG++++ + + I G I
Sbjct: 357 EPEIAHVGETEAELHARHAGHEVYRFPFNRIDRAITEDATEGWIRIYAAEFDGKIFGADI 416
Query: 443 IGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
+G GELI+E LA G ++ H +P+ A R A
Sbjct: 417 LGAHAGELISEIGLAMRNGITLRQLSDTIHPYPSYALGNRRA 458
>UniRef50_A0FRY7 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=3;
Burkholderia|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Burkholderia
phymatum STM815
Length = 466
Score = 225 bits (551), Expect = 2e-57
Identities = 143/455 (31%), Positives = 229/455 (50%), Gaps = 15/455 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D +++GSG GG + A + G +V VE+ +GG+C V C+PSK + ++ + H+A+
Sbjct: 8 DTLILGSGQGGKLLAWHLGRSGQRVAVVERQ-WVGGSCPAVACLPSKNEIWSARVAHLAR 66
Query: 93 H--DFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
H DF G TG V D K+ E K V+ ++ + LV GVG V P
Sbjct: 67 HAADF---GATTGPVAIDMAKVRERKRGMVEREAAFHVQAYESSGAELVMGVGRFVGPKT 123
Query: 151 VEVH-GEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVI 207
VEV + G T++ + +++ G+ + PG+ E +T GAL L+ P ++V+
Sbjct: 124 VEVQLNDGGTRTLSGRQVVVNVGTHAAIPDVPGLRAAEP--LTHIGALDLDRAPSHLIVL 181
Query: 208 GAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVL 267
G G IG+E+ Y R G+ VT IE T + D +V + +IL +G+ L + +
Sbjct: 182 GGGYIGVEMAQAYVRFGSHVTIIERSTRLMARE-DADVGAEMLRILRAEGIDVVLDARTV 240
Query: 268 GVK-KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPV 326
V+ + G+ ++V V G LD +L++ GR P T +GL+ GI LD+RG I V
Sbjct: 241 SVEGRSGTQVRVVVRTPSGDR--TLDGSDILVAAGRVPNTASIGLEHAGIQLDERGYIRV 298
Query: 327 NNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEV 386
N++ QT+ P ++AIG+V P H + D+ + + + G IP ++T P +
Sbjct: 299 NDRLQTSAPDVWAIGEVAGSPQFTHVSVDDFRIVRDNLAGGNRGTGDRLIPYTLFTDPPL 358
Query: 387 GWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPG 446
VG +E D +++G A +V P R + ET+GF+KVL D ILG +IG
Sbjct: 359 ARVGLSESDAQRQGIAVRVATLPMNNVLRTEATDETQGFMKVLVSANDDRILGFTMIGSE 418
Query: 447 GGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
GE++ A + + +H T AE L
Sbjct: 419 AGEVMAAMQTAMLADLPYQKLRDAVISHLTVAEGL 453
>UniRef50_Q0LM28 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
- Herpetosiphon aurantiacus ATCC 23779
Length = 472
Score = 224 bits (548), Expect = 4e-57
Identities = 145/456 (31%), Positives = 236/456 (51%), Gaps = 17/456 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL+VIG G G A A LG K+ +E + LGG C GC+PSK+L+H + + H
Sbjct: 3 DLLVIGGGSAGITFAKFGASLGAKITVIEANK-LGGDCTWTGCVPSKSLIHAAKIAHTTA 61
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLT--GGIAMLFQKNKVNLVKGVGTIVAPNK 150
+ GI + + + DF +M Y + + + + ++ +++G
Sbjct: 62 TAARY-GI-SAQPSIDFAAVMGYVHSVQQQIYQHDDAPEVLRQAGARVIEGRARFYDDQT 119
Query: 151 VEVHGEKGVETVNTKNILIASGS--EVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
VEV+GE + K+ IA+GS ++ PG+ E +T+ LE++PK+++V+G
Sbjct: 120 VEVNGE----LLRAKHFCIATGSHPKIPTIPGLA--EAGYLTNEDVFLLEALPKRIVVLG 173
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
G IG ELG RLGA+VT I+ + D + L + L +G++ L TK L
Sbjct: 174 GGPIGCELGQALFRLGAEVTIIQQGPRLLPKD-DHAMGAALAQALKSEGLQLYLNTKTLK 232
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
V+ + ++ ++ A + ++ D +L++ GR P LGLD GI D RI V++
Sbjct: 233 VELQAGAKQLTIQTANNQPQTIV-ADAILVAAGRTPNLHNLGLDAAGILYDPEQRIHVDH 291
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDE-GIVCVEGIKGMPVHFNYDAIPSVIYTSPEVG 387
+T+ P ++A GDVI H A E G+V + Y+ +P +T PEVG
Sbjct: 292 YLRTSNPRVFACGDVIGRYQFTHVAAQEAGLVLRNALFPGQSAMKYELVPWATFTDPEVG 351
Query: 388 WVGKTEEDLK-KEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPG 446
VG E+ + K G + +V + P+ AN RA+T T+GF K+L+ + I+G HIIG G
Sbjct: 352 HVGLNEDQARAKYGSSLRVYELPWSANDRARTEDATQGFTKILAVGRKEQIVGVHIIGQG 411
Query: 447 GGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALR 482
G++IN AVLA G +A + + + +PT ++ L+
Sbjct: 412 AGDMINAAVLAMGTGVSASKLGGLINVYPTRSQGLK 447
>UniRef50_Q11LG9 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region precursor; n=31;
Alphaproteobacteria|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region precursor -
Mesorhizobium sp. (strain BNC1)
Length = 475
Score = 223 bits (546), Expect = 6e-57
Identities = 147/463 (31%), Positives = 238/463 (51%), Gaps = 19/463 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+ VIG+G GG A AA LG VV +E+ +GG CLN GC+PSKAL+ ++ H
Sbjct: 8 DICVIGAGSGGLTVAAAAASLGASVVLIERGK-MGGDCLNYGCVPSKALIASARQAHRLS 66
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAM-LFQKNKVNLVKGVGTIVAPNKV 151
H GI E + DF ++ + A+ + + F V ++ G P V
Sbjct: 67 HG-GSLGIAAVEPSIDFARVAGHIEQAIAAIAPNDSKERFTALGVEVISAQGHFKDPRTV 125
Query: 152 EVHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
G + + + +IA+GS + P PG++ + +T+ L+ P ++++G
Sbjct: 126 VAGGSE----IRARRFVIATGSSPAIPPIPGLS--DVPFLTNETTFGLKQSPAHLIIVGG 179
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
G IG+E ++RLGADVT +E T +G D E+A +++ L K+G+ + V
Sbjct: 180 GPIGMERAQAHRRLGADVTVLEADTVLGKE--DPELALGVKQALLKEGVAILEHARAERV 237
Query: 270 KK-EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
++ +G+ I+V V KG + +D +LI+ GRRP + L L+ G+A G I ++
Sbjct: 238 ERYKGTGIRVHVADEKGAHS--IDGSHLLIATGRRPNVEALALENAGVAYGPGG-ITISP 294
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAE-DEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVG 387
K +TT I+AIGDV GP H A G+V + +PV N++ IP V +T PE+
Sbjct: 295 KLRTTNRRIFAIGDVAGGPQFTHVANYHAGLVIRAILFRLPVKANHEHIPRVTFTDPELA 354
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
+G TE + ++ G KV + F N RA G T+GF+K++ + ILG I+G G
Sbjct: 355 QIGLTENEARRRGLQVKVLRSSFSENDRAHAEGHTDGFIKLIVGR-RGRILGVSILGRGA 413
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYS 490
GE+++ LA D+++ +PT E + A L+ ++
Sbjct: 414 GEMMHFWSLALSRRMRVHDISQYVAPYPTLGEIGKRAALSYFA 456
>UniRef50_Q2HI16 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 471
Score = 223 bits (544), Expect = 1e-56
Identities = 141/466 (30%), Positives = 227/466 (48%), Gaps = 19/466 (4%)
Query: 27 ATTHDADLVVIGSG-PGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNS 85
AT D + +G G P +A +++ G K +E P + G C V C+P+K LLH++
Sbjct: 2 ATPEQYDFIALGGGEPAKLLAWDLSSKYGKKCAVIEHGP-ISGACPTVACMPTKTLLHSA 60
Query: 86 HLYHMAKH-DFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGT 144
L H+A+ G D K+ K V G+ +F + K L++G G
Sbjct: 61 QLAHLARQAQASTPGAAGNGFNADMAKVFARKQEVVDGMADLFLGIFAETKAELIRGHGE 120
Query: 145 IVAPNKVEVHGEKGVETVNTKNILIASGSEV---TPFPGVTFDEKQIITSTGALSLESVP 201
V P + +G + + +LI +GS+ T PG+ + +T L ++++P
Sbjct: 121 FVDPKTISCNGR----LLTAETVLINTGSKAFVDTSIPGLA--DANPLTHVELLDIKTLP 174
Query: 202 KKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFK 261
++++G G +G+E Y R G+ VT IE I D +V L ++L+++G+ F
Sbjct: 175 SHLIILGGGYVGIEFAQAYARFGSRVTVIERNAQILAKE-DSDVVAELTRLLAREGIDFL 233
Query: 262 LGTKVLGVK-KEGSTIKVDVE---AAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIA 317
T V V GS + + + G + +L++ GR P T LGL GI
Sbjct: 234 TSTSVTHVSGTSGSEVTLTLSHPTPGAGAAPTSIRGTHLLVAAGRTPTTANLGLAAAGIK 293
Query: 318 LDDRGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDA-- 375
L G I V+ + +T+VPG++A GD P H D+ V + + G P
Sbjct: 294 LTPTGHIAVDAQLRTSVPGVFAAGDCAGSPYFTHMGWDDYRVLLGVVTGAPREAGTMGRQ 353
Query: 376 IPSVIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTD 435
+PSV++T+PE+ VG EE+ KK+G Y+V + P A RA+ GETEGF K L ++ +
Sbjct: 354 VPSVLFTTPELAHVGLREEEAKKKGVGYRVVRAPMGAFLRARALGETEGFAKALVEEEGE 413
Query: 436 VILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
+LG +GPG GEL+ L + G + +++ + HPT AE L
Sbjct: 414 RVLGFTALGPGAGELLPVVQLVMKLGLSYKELVDLTIVHPTMAEGL 459
>UniRef50_UPI00015BC7B4 Cluster: UPI00015BC7B4 related cluster; n=1;
unknown|Rep: UPI00015BC7B4 UniRef100 entry - unknown
Length = 481
Score = 222 bits (543), Expect = 1e-56
Identities = 142/458 (31%), Positives = 240/458 (52%), Gaps = 22/458 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+ ++G G + AAIKA+ +G +V+ E + +GGTCLN GCIPSK L+ ++ ++
Sbjct: 20 DIFILGGGSAAFAAAIKASDIGARVLVAENN-IIGGTCLNRGCIPSKYLIEVANTFYTPN 78
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKV-NLVKGVGTIVAPN-- 149
+ G+E + + ++E K +K L +K K N+++ I N
Sbjct: 79 RN-PFPGVELATGNLNIRNIIEKKEELLKEL--------RKEKYWNVLEAYPQIEYRNLR 129
Query: 150 -KVEVHGEK--GVETVNTKNILIASGSEVTPFPGVTFDEK-QIITSTGALSLESVPKKML 205
K G G + V+ +IA+GS+ P + EK + TS +++ +PK ++
Sbjct: 130 GKFVDEGTALVGEDKVSFYKAIIATGSKPL-IPSIKGIEKVRYYTSDNIFNIDHLPKHLI 188
Query: 206 VIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTK 265
+IG G IGLELG + R G+ VT +E+ I + + E+ L+++L K+G+ +
Sbjct: 189 IIGGGAIGLELGQAFLRFGSKVTIVEYFQEI-AMAQEPEIRTKLKEVLEKEGISILTNAE 247
Query: 266 VLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIP 325
+ + +E I ++++ + NK + +LI+ GR P TK +GL+ + RG I
Sbjct: 248 ITNIWEEDGQITLELKHEE--NKTTIHGTDLLIATGREPNTKDIGLEATSVMTSTRGFIQ 305
Query: 326 VNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVE-GIKGMPVHFNYDAIPSVIYTSP 384
N QTT IYA GD + ML A EG + E + G +Y ++P+ I+T P
Sbjct: 306 ANEFMQTTNENIYAAGDCVGKMMLVTVAAMEGGIAAENALLGNKKKADYLSVPNAIFTYP 365
Query: 385 EVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 444
EV VG E + +K+G +V RA + +TEG +K++ +K T I+G HI+
Sbjct: 366 EVARVGMGELEARKQGLEVEVRTLDLSKVPRAALSLQTEGLIKMIVEKNTRKIIGVHILA 425
Query: 445 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALR 482
P G E+I++AVL+ +YG ED+ + +PT +EA++
Sbjct: 426 PHGAEVIHKAVLSIKYGFTIEDIIQSIDVYPTLSEAIK 463
>UniRef50_P66007 Cluster: Probable soluble pyridine nucleotide
transhydrogenase (EC 1.6.1.1) (STH) (NAD(P)(+)
transhydrogenase [B-specific]); n=19; Bacteria|Rep:
Probable soluble pyridine nucleotide transhydrogenase
(EC 1.6.1.1) (STH) (NAD(P)(+) transhydrogenase
[B-specific]) - Mycobacterium bovis
Length = 468
Score = 221 bits (540), Expect = 3e-56
Identities = 151/457 (33%), Positives = 232/457 (50%), Gaps = 10/457 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+VVIGSGPGG AAI +A+LG V VE+ LGG C+N G IPSK L + LY
Sbjct: 5 DIVVIGSGPGGQKAAIASAKLGKSVAIVERGRMLGGVCVNTGTIPSKTL-REAVLYLTGM 63
Query: 93 HDFKQRGIETG-EVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
+ + G + ++ + + + +N+V+L+ G G + P+ +
Sbjct: 64 NQRELYGASYRVKDRITPADLLARTQHVIGKEVDVVRNQLMRNRVDLIVGHGRFIDPHTI 123
Query: 152 EVHGEKGVE--TVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
V + E TV I+IA+G+ GV FDE++++ S G L L+S+P M+V+GA
Sbjct: 124 LVEDQARREKTTVTGDYIIIATGTRPARPSGVEFDEERVLDSDGILDLKSLPSSMVVVGA 183
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
GVIG+E S++ LG VT +E ++ D EV + L+ L + F+ G +V V
Sbjct: 184 GVIGIEYASMFAALGTKVTVVEKRDNMLDF-CDPEVVEALKFHLRDLAVTFRFGEEVTAV 242
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
GS V A+ K++ + V+ S GR+ T L L G+ + RGRI V+++
Sbjct: 243 DV-GSAGTVTTLAS---GKQI-PAETVMYSAGRQGQTDHLDLHNAGLEVQGRGRIFVDDR 297
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWV 389
FQT V IYA+GDVI P LA + ++G + G P + P IY+ PEV +V
Sbjct: 298 FQTKVDHIYAVGDVIGFPALAATSMEQGRLAAYHAFGEPTDGITELQPIGIYSIPEVSYV 357
Query: 390 GKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGE 449
G TE +L K Y+VG + +R + G++ G +K+L +LG HI G E
Sbjct: 358 GATEVELTKSSIPYEVGVARYRELARGQIAGDSYGMLKLLVSTEDLKLLGVHIFGTSATE 417
Query: 450 LINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANL 486
+++ G + E + +PT +EA + A L
Sbjct: 418 MVHIGQAVMGCGGSVEYLVDAVFNYPTFSEAYKNAAL 454
>UniRef50_Q98RI8 Cluster: DIHYDROLIPOAMIDE DEHYDROGENASE; n=1;
Mycoplasma pulmonis|Rep: DIHYDROLIPOAMIDE DEHYDROGENASE
- Mycoplasma pulmonis
Length = 455
Score = 220 bits (538), Expect = 6e-56
Identities = 148/456 (32%), Positives = 231/456 (50%), Gaps = 22/456 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D V+IGSGPGGY A+ ++LG KV E+ GG+C+N GC+P+K L+ + Y + K
Sbjct: 5 DFVIIGSGPGGYSLALILSKLGKKVAIAERK-NFGGSCINEGCVPTKGLVKVARTYELIK 63
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ K GI+ + +FD+K++++ K L I + N V + K ++ +E
Sbjct: 64 NSSKF-GIKVNDFSFDWKQIIKRKNEIKDTLNNSIEKNLELNNVKIFKAEAKVLKDKSIE 122
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTFD---EKQIITSTG-ALSLESVPKKMLVIG 208
V+ K + + I+IA+GS D EKQ++ + L ++ VPK + IG
Sbjct: 123 VNNTK----IYAEKIIIATGSRARKISFDGSDKALEKQVLVDSNYLLDMQEVPKSIAFIG 178
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
AG I LELG V LG+DVT +E I D +V + + K L ++ +K+ TKVL
Sbjct: 179 AGPISLELGYVLSALGSDVTLLEGRDQI-LANFDHDVREEVLKYLEQKNIKYFTSTKVLK 237
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
++G V G +V++ + + +S+GR + ++ + + L+ I V++
Sbjct: 238 YDQDGLHFSV------GEKNKVINPEKIALSVGREANLE--AVEDLDLELNPNKTIKVDD 289
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEG-IKGMPVHFNYDAIPSVIYTSPEVG 387
K +T++ GIYA+GDV ML+ A G V V I V +Y +P IY SPE+
Sbjct: 290 KLETSIKGIYALGDVTGKMMLSTIAYKHGDVIVNNLINNKEVKLDYKKVPHTIYLSPEIS 349
Query: 388 WVGKTEEDLKKE-GRAYKVGKFPFLANSRAKTNGET-EGFVKVLSDKTTDVILGTHIIGP 445
+G +EE+ KK G K P R +G GF K++ +K T +LG II
Sbjct: 350 SIGLSEEEAKKTYGENLLAIKIPSERLPRNHADGNLGYGFFKLIINKDTKQVLGASIILE 409
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
+INE +A D+A+ H HPT AEAL
Sbjct: 410 NSSLIINEISIAMNNDLTIYDLAKSPHVHPTLAEAL 445
>UniRef50_Q1JWV4 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=1; Desulfuromonas
acetoxidans DSM 684|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Desulfuromonas
acetoxidans DSM 684
Length = 459
Score = 220 bits (538), Expect = 6e-56
Identities = 139/457 (30%), Positives = 233/457 (50%), Gaps = 16/457 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D++VIGSG GG A+ AAQ G+K +E+D GGTCLN GCIPSK L++ + + + +
Sbjct: 5 DVIVIGSG-GGTKIALPAAQRGLKTALIERD-AFGGTCLNRGCIPSKMLIYPADMIYAIR 62
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIA-MLFQKNKVNLVKGVGTIVAPNKV 151
+ + ++ DF +++ V ++ A + Q + ++ + G G VA V
Sbjct: 63 NARRVNVYADQQIDGDFSALVQRVTKTVSQMSEHFADKVRQLDHLDYINGSGHFVADKVV 122
Query: 152 EVHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
EV+G + + I IA+G+ + PG+ + +TST AL ES+PK+M++IGA
Sbjct: 123 EVNGRQ----LTAPTIFIATGARPSIPEIPGLA--DTPYMTSTEALRCESLPKRMVIIGA 176
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
I ELG VY+ G T FL + + + +T +Q +G + + V
Sbjct: 177 SYIACELGHVYEAFG---TETHFLVRSALLRQEDDDIRTAFADDFRQRHTLHMGFEPVEV 233
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
+ E + + + G ++ L + +L+S G P T LGL+ I +D+G I V++
Sbjct: 234 RWEDELFCIRLRHNEKGTEKELYAEALLVSTGVDPVTDDLGLEHTAITCNDKGFIEVDDH 293
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH--FNYDAIPSVIYTSPEVG 387
QT VPG+YA+GD + + H EG + + P Y A+P ++T PE+
Sbjct: 294 LQTAVPGVYALGDCVGNYLFRHSVNFEGEYLMRTLFEAPSDEPIVYGAVPRAVFTVPEMA 353
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG E+ L+++G Y VG+ + ++ GF K+L D+ + +LG HIIG
Sbjct: 354 AVGAGEKQLQQQGVDYVVGRADYADSNMGMARMLENGFAKLLFDRNSRRLLGAHIIGEEA 413
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
+LI+ +L + ED+ ++ + HP E +R+A
Sbjct: 414 SDLIHMLILGLQQQVTVEDLLQMIYIHPALPELIRDA 450
>UniRef50_Q8G5E0 Cluster: Dihydrolipoyl dehydrogenase; n=4;
Bifidobacterium|Rep: Dihydrolipoyl dehydrogenase -
Bifidobacterium longum
Length = 496
Score = 219 bits (536), Expect = 1e-55
Identities = 162/500 (32%), Positives = 247/500 (49%), Gaps = 48/500 (9%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DLV+IG+GPGGY A++AA+LGMKV VE+D T+GGTCLN GCIPSKAL+ +H
Sbjct: 6 DLVIIGAGPGGYSTALRAAELGMKVALVERDATVGGTCLNRGCIPSKALITATHTIDTV- 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAML--------FQKNK--------- 135
H + G+ DF + +Y+ VK + GG+A L F+ N
Sbjct: 65 HRAAELGVNASVNGIDFGTLRDYRLRVVKTMVGGLAGLLAHRGITVFRANAAFHADETAP 124
Query: 136 ------VNLVKGV--GTIVAPNKVEVHGEKG-VETVNTKNILIASGSEVTPFPGVTFDEK 186
V+LV I+ +K +V G + NI+IA+G++ P PG F
Sbjct: 125 ATSNHIVHLVPSPDQSDILTYHKADVPEPSGPTMDLTATNIVIATGAKPRPLPGNPF-AG 183
Query: 187 QIITSTGALSLESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVA 246
+I ST AL + P ++IGAG I LE S++ G+ VT + + D
Sbjct: 184 ALIDSTQALEVNEFPSSAVIIGAGAIALEFASMWNAAGSKVTLLIRKDRVLSAW-DRRAG 242
Query: 247 KTLQKILSKQGMKFKLGTKVLGVKKE---GSTIKVDVEAAKGGNKEVLDCDVVLISIGRR 303
TL + L + G+ V V G+T+ E G ++ + ++ L++IGR
Sbjct: 243 TTLTRELKRHGVNIITRASVTHVDTGANLGATVHYTCEGQDG--EQSVWGEIALVAIGRD 300
Query: 304 PYTKGLGLDKVGIALDDRGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEG 363
P T G+ +DD G + + +T PG++A+GDV G LAH+A ++GIV E
Sbjct: 301 PITDPAW----GVTIDDHGHVATDAYGRTDKPGVWAVGDVTAGHALAHRAFEQGIVIAET 356
Query: 364 IKGM-PVHFNYDAIPSVIYTSPEVGWVGKTEE--DLKKEGRAYKVGKFPFLANSRAKTNG 420
I G+ P + +P ++++ PE VG T E +++ K +P LAN+R +G
Sbjct: 357 IAGLNPKPVDEATVPQIVFSFPEAASVGLTVEQAQAREDLIEIKETNYPMLANARMLMSG 416
Query: 421 ETEGFVKVLS-----DKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHP 475
T G + ++S + T +LG H++ ++I EA D AR+ H HP
Sbjct: 417 -TAGSLTIVSGCDAANPDTPRVLGVHMVSQMASDIIAEAEQLVGNHVPLADAARLVHPHP 475
Query: 476 TCAEALREANLAAYSGKPIN 495
T +E L EA L A G+P++
Sbjct: 476 TFSETLGEALLKA-DGRPLH 494
>UniRef50_P23189 Cluster: Glutathione reductase; n=42;
Proteobacteria|Rep: Glutathione reductase - Pseudomonas
aeruginosa
Length = 451
Score = 219 bits (536), Expect = 1e-55
Identities = 144/456 (31%), Positives = 231/456 (50%), Gaps = 25/456 (5%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
D DL VIG+G GG AA AA G +V +V + LGGTC+NVGC+P K L++ +H
Sbjct: 4 DFDLFVIGAGSGGVRAARFAAGFGARV-AVAESRYLGGTCVNVGCVPKKLLVYGAHF--- 59
Query: 91 AKHDFKQR---GIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVA 147
DF+Q G GE FD+ ++ K ++ L G L + V L++G ++
Sbjct: 60 -SEDFEQARAYGWSAGEAQFDWATLIGNKNREIQRLNGIYRNLLVNSGVTLLEGHARLLD 118
Query: 148 PNKVEVHGEKGVETVNTKNILIASGS--EVTPFPGVTFDEKQIITSTGALSLESVPKKML 205
+ VEV G++ + K+IL+A+G +V PG ++ ITS A LE +P+++L
Sbjct: 119 AHSVEVDGQR----FSAKHILVATGGWPQVPDIPG----KEHAITSNEAFFLERLPRRVL 170
Query: 206 VIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTK 265
V+G G I +E S++ LGA+ T + + + G D V + L+ L K+G+ + +
Sbjct: 171 VVGGGYIAVEFASIFNGLGAETTLL-YRRDLFLRGFDRSVREHLRDELGKKGLDLQFNSD 229
Query: 266 VLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIP 325
+ + K+ AA + VL+ D V + GRRP LGL+ + L D+G I
Sbjct: 230 IARIDKQADGSL----AATLKDGRVLEADCVFYATGRRPMLDDLGLENTAVKLTDKGFIA 285
Query: 326 VNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH--FNYDAIPSVIYTS 383
V+ +QT+ P I A+GDVI L A EG+ + + +Y IP+ +++
Sbjct: 286 VDEHYQTSEPSILALGDVIGRVQLTPVALAEGMAVARRLFKPEEYRPVDYKLIPTAVFSL 345
Query: 384 PEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHII 443
P +G VG TEE+ G K+ + F T+ + + +K++ D D +LG H++
Sbjct: 346 PNIGTVGLTEEEALSAGHKVKIFESRFRPMKLTLTDDQEKTLMKLVVDAHDDRVLGCHMV 405
Query: 444 GPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAE 479
G GE++ +A + GA + HPT AE
Sbjct: 406 GAEAGEILQGIAVAMKAGATKQAFDETIGIHPTAAE 441
>UniRef50_Q0F0Y4 Cluster: Soluble pyridine nucleotide
transhydrogenase; n=1; Mariprofundus ferrooxydans
PV-1|Rep: Soluble pyridine nucleotide transhydrogenase -
Mariprofundus ferrooxydans PV-1
Length = 464
Score = 217 bits (531), Expect = 4e-55
Identities = 140/462 (30%), Positives = 231/462 (50%), Gaps = 11/462 (2%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
D D++++GSGP G AA +AA++G + +E+ P++GG L G IPSKAL ++L
Sbjct: 2 DYDILIVGSGPAGQHAAWQAARMGKRAAIIERKPSIGGAGLQTGTIPSKALREAAYLASR 61
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
+ R T + + K + I K+ V L+ G + + +
Sbjct: 62 SGVQ-GMREASTAARHGVLAEAVRRKDMVIAQQESVIVKRLLKSGVALIPGEASFIDEHT 120
Query: 151 VEVHGEKGVET-VNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
+EV G ++ IL+A+GS + FD++ ++ ST L L+ +PK +LV+G
Sbjct: 121 LEVVDANGASRQLSADVILLATGSRPHRPSDIPFDKQTVLDSTSILKLKRLPKSLLVVGG 180
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
GVI E S++ LG V+ ++ + + +V L + G++ + +V+ V
Sbjct: 181 GVIACEFVSIFAALGVAVSVVDSHAQLLAY-LSEDVVAVLAESFDNMGVELHMQQRVVAV 239
Query: 270 KKE-GSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
++E G T+ + + G K L +VVL ++GR P + L K GI LD +G I VN
Sbjct: 240 RREEGRTLTL----LESGQK--LYSEVVLYALGRVPNAQSLNTPKAGITLD-QGWITVNK 292
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGW 388
+FQ++VP IYA+GD+I P LA ++G V G +P IY PE+ W
Sbjct: 293 QFQSSVPHIYAVGDLIGRPALASTGMEQGRAAVLHAFGGSGQAMPANLPMAIYAIPEISW 352
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VGKTE++ K++ Y VG+ + ++R + G+ G VK++ D + ++G HI+G
Sbjct: 353 VGKTEKEAKRDQIDYVVGRGYYKESARGQIIGDANGLVKLIVDAHSHRLIGAHIVGEHAS 412
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYS 490
ELI+ L + D+ +PT AE + A L S
Sbjct: 413 ELIHTGQLLMNFNGTVHDLVANAFNYPTLAECYKLAALDCLS 454
>UniRef50_Q3SL16 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex dihydrolipoamide dehydrogenase E3 component;
n=2; Proteobacteria|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex dihydrolipoamide dehydrogenase E3
component - Thiobacillus denitrificans (strain ATCC
25259)
Length = 998
Score = 216 bits (528), Expect = 1e-54
Identities = 148/460 (32%), Positives = 230/460 (50%), Gaps = 13/460 (2%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
D +VV+G GPGG A A G+KV+ V +P GG CL GCIPSKA +
Sbjct: 530 DVQVVVVGGGPGGEDCARDLADHGVKVMMVNNEPFPGGECLWRGCIPSKAWRAAADNIRN 589
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKN-KVNLVKGVGTIVAPN 149
HD + T ++ ++ +++ V+ G +A+ K K+++ +G G V +
Sbjct: 590 RAHDAEMGVDGTANPKLNWAQVEKHR-RWVQTSRGEMALKADKGMKIDVREGYGEFVDAH 648
Query: 150 KVEVHGEKG-VETVNTKNILIASGSE--VTPFPGV--TFDEKQIITSTGALSLESVPKKM 204
+++ +G TV+ +IA+G+ V P PG ++TS +L + PKK+
Sbjct: 649 TLKITPPEGEAYTVSFGAAVIATGAPAFVPPIPGARENLATGGVVTSDTIWNLANPPKKL 708
Query: 205 LVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQ-GMKFKLG 263
++G GVIG+E+ +++ G +V +E I I+ E+ K L L K+ +
Sbjct: 709 GIVGGGVIGVEMAQIFRDFGTEVLMLERHDRILAE-IEEEIGKVLIASLEKEITVVTSAD 767
Query: 264 TKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGR 323
+ +G K T++ A K G + DCDVVL++ G+RP T L LDKVG+ALD
Sbjct: 768 IREVGGKPGKMTLRY---ADKEGAESTFDCDVVLMATGKRPDTSRLNLDKVGVALDGAA- 823
Query: 324 IPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTS 383
I V+ + T+ P IYA+GDVI G MLAH A +G V + G ++ D V ++
Sbjct: 824 IKVDARCCTSTPNIYAVGDVIGGYMLAHTAATQGRVAASNLLGHASEYDQDRDCGVTFSR 883
Query: 384 PEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHII 443
P+ G+VG + K +G K P +++A GETEG +K+++DKTT I+G H +
Sbjct: 884 PQAGFVGLSVAQAKAKGIDAVEAKMPMSIDAKAMITGETEGMIKLVADKTTGRIIGVHYL 943
Query: 444 GPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
LI V+ VA+ HPT E E
Sbjct: 944 ADHTDTLIGTGVMMVAGEMTLTQVAKAIFPHPTQTELFGE 983
>UniRef50_Q2RZZ0 Cluster: Mercuric reductase; n=1; Salinibacter
ruber DSM 13855|Rep: Mercuric reductase - Salinibacter
ruber (strain DSM 13855)
Length = 574
Score = 215 bits (525), Expect = 2e-54
Identities = 137/458 (29%), Positives = 224/458 (48%), Gaps = 13/458 (2%)
Query: 29 THDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLY 88
T D D++VIG G GG AA A LG K +E+D LGG C GC+PSK LL + +
Sbjct: 88 TTDYDVLVIGGGAGGLSAAGIATNLGAKTAMIERD-ALGGDCTWTGCVPSKTLLKAATVV 146
Query: 89 HMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGL--TGGIAMLFQKNKVNLVKGVGTIV 146
H A+ K G+ V DF +M++ + + +F+ +++ +G +
Sbjct: 147 HQARTASKY-GLTDQSVDVDFGGVMDHVRQVRQEVYEEADAPEIFEDLDIDVREGDAHFI 205
Query: 147 APNKVEVHGEKG-VETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKML 205
+ V V G E V + +++A+G+ P E ++T+ LE P+++
Sbjct: 206 DAHTVGVERADGSTEQVTGRYVIVAAGARPLVPPIEGLGEVDVLTNESLFELEEQPERLA 265
Query: 206 VIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTK 265
++G G IG E+ + RLG +V ++ I D E+A TL++ L ++G+++ LG +
Sbjct: 266 IVGGGPIGTEMAQAFARLGTEVVVLDMADRILS-NDDAELAATLRETLEEEGVEYVLGAQ 324
Query: 266 VLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIP 325
V V + G TI + G + ++ D +L++ GR GL LD GI +G I
Sbjct: 325 VEKVAQSGGTITISA-----GEQGPVEADALLLATGRTANVDGLHLDAAGIDYTRQG-IT 378
Query: 326 VNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCV-EGIKGMPVHFNYDAIPSVIYTSP 384
V+++ +T+ +YA+GDV H + V V + +P + D +P V YT P
Sbjct: 379 VDDRCRTSQGHVYAVGDVTGRYQFTHMSNHMAKVAVTNALLKVPSKIDADHVPWVTYTEP 438
Query: 385 EVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 444
E+ VG DL ++G +Y+ +FP+ RA T ET G +KV + T ILG ++G
Sbjct: 439 ELAHVGAHAADLDEQGVSYETYRFPYDQLDRAITESETTGQIKVHATSLTGKILGASVLG 498
Query: 445 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALR 482
GELI +A G ++ H +P E +R
Sbjct: 499 ERAGELITAFTIAMRNGVTLRNIGDTIHPYPAYGEGVR 536
>UniRef50_Q2JK69 Cluster: Pyridine nucleotide-disulfide
oxidoreductase; n=4; Cyanobacteria|Rep: Pyridine
nucleotide-disulfide oxidoreductase - Synechococcus sp.
(strain JA-2-3B'a(2-13)) (Cyanobacteria
bacteriumYellowstone B-Prime)
Length = 532
Score = 214 bits (522), Expect = 5e-54
Identities = 157/468 (33%), Positives = 228/468 (48%), Gaps = 24/468 (5%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+VVIG+G G V A AAQL KV+ VE LGG CL GC+PSKALLH +H H +
Sbjct: 47 DIVVIGAGAAGLVVASAAAQLKAKVLLVEGSDRLGGDCLWYGCVPSKALLHVAHTVHRIR 106
Query: 93 HDFKQRGIE---TGEVTFDFKKMMEYKANAVKGLTGGIAM--LFQKNKVNLVKGVGTIVA 147
+ ++ D+ K+ E+ +A + F++ V LV G V
Sbjct: 107 QAMAAGWVTLPGPAGISVDYLKVYEHIRSAQSYIANHADSPDRFRQLGVELVFAKGHFVD 166
Query: 148 PNKVEVHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKML 205
EV G + V + +IA+GS V P PG+ E +T+ L +PK +
Sbjct: 167 GRTFEVAGRQ----VQARAFVIATGSRPWVPPLPGLA--EAGYLTNESIFDLTRLPKSVA 220
Query: 206 VIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTK 265
VIGAG +G EL RLG++VT I I D E A+ +Q+ L++ G++ +
Sbjct: 221 VIGAGPVGCELSQALARLGSEVTLIASRERILPKE-DPEAAQVVQQQLTQDGIRILTRVR 279
Query: 266 VLGVKKEGSTIKVDVEAAKG-----GNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDD 320
V +E + ++A G +V+ + +L++ GR P +GLGL+ G+
Sbjct: 280 ATAVGQEQGAKLLSLKANSGAGTAAAGDQVIRAEEILVAAGRIPNVEGLGLEAAGVQYTP 339
Query: 321 RGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPV-HFNYDAIPSV 379
+G I VN K QT P IYA GDVI GP H A EG V + P+ Y IP
Sbjct: 340 QG-IQVNAKLQTRNPRIYACGDVIGGPQFTHVAAYEGAVALVNALFFPLSQARYRVIPWA 398
Query: 380 IYTSPEVGWVGKTEEDLKKE-GRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVIL 438
I+T PE+ VG TE + +++ G+ V K F RA+ GF K++ + IL
Sbjct: 399 IFTEPELARVGLTESEARQQYGKDVVVLKQEFADVDRAQAEAAPLGFAKLIC-RRNGQIL 457
Query: 439 GTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANL 486
G H++G GELI+E VLA + + H +PT +E +A L
Sbjct: 458 GAHLVGSQAGELIHEVVLAMSRRLPVSALTGI-HIYPTRSEVNAKAAL 504
>UniRef50_Q1PWS8 Cluster: Similar to NAD(P) oxidoreductase,
FAD-containing subunit; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to NAD(P) oxidoreductase,
FAD-containing subunit - Candidatus Kuenenia
stuttgartiensis
Length = 472
Score = 214 bits (522), Expect = 5e-54
Identities = 146/461 (31%), Positives = 230/461 (49%), Gaps = 12/461 (2%)
Query: 30 HDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYH 89
+D ++VIG+G GG V A AA LG +V +E + +GG CLN GC+PSK L ++H+
Sbjct: 3 YDYHIIVIGAGSGGLVVASGAASLGARVALIEAEK-MGGDCLNAGCVPSKTFLKSAHIAK 61
Query: 90 MAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAM-LFQKNKVNLVKGVGTIVAP 148
A D G+ D +M+ ++ + + ++ V+++ G G +
Sbjct: 62 -AIRDASMYGLTADLKKVDITTVMDRVNKVIREIEPHDSRERYEGLGVDVILGFGELQDR 120
Query: 149 NKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
+ V++ G ET+ K I+IA+GSE P +E T+ L+ +P ++V+G
Sbjct: 121 HTVKI----GNETITGKYIVIATGSEPAVPPIHGLNEVNYQTNRTIFHLKELPGHLIVLG 176
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
+G IG+ELG ++ LG+ VT I + D EV ++K L G++ LG
Sbjct: 177 SGPIGIELGQGFRHLGSQVTIINRSPGLFKKD-DPEVGPLMEKQLKDDGIELLLGIAYRE 235
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
V+++ I V++E G ++ D +L++ GR P TK LGLDKVG+ +D++G I +
Sbjct: 236 VRQDSDVISVEIEHE--GKGRIITGDQLLVATGRLPATKNLGLDKVGVRVDEKGYIVTDK 293
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKA-EDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVG 387
K +T+V IYA GDV H A GI+ I + +Y A+P YT PEV
Sbjct: 294 KQKTSVKNIYACGDVTGHYQFTHMAGYQAGIIIRNIIFKLCAKVDYSAVPWTTYTKPEVA 353
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG TE K G K A RAK + GF+K+ K +I G ++G
Sbjct: 354 HVGYTEPMASKAGTYKSSLKVDLSAIDRAKAEDDRVGFLKLNLGKKGRII-GATLVGEKA 412
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAA 488
GE+I +A + A + ++PT +E L+ A+L A
Sbjct: 413 GEMIPAITIAIKQKLTAGIFMNMIFSYPTESEILKSASLEA 453
>UniRef50_Q8F4C6 Cluster: Dihydrolipoamide dehydrogenase; n=4;
Leptospira|Rep: Dihydrolipoamide dehydrogenase -
Leptospira interrogans
Length = 460
Score = 213 bits (520), Expect = 9e-54
Identities = 139/459 (30%), Positives = 221/459 (48%), Gaps = 22/459 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D++VIG+G GG +++G K+ +EK+ GGTCLN GCIPSK L++ + + + K
Sbjct: 5 DIIVIGTG-GGTKLVTPPSKIGYKIAVIEKENP-GGTCLNRGCIPSKMLIYPAEILSLTK 62
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKN-KVNLVKGVGTIVAPNKV 151
H K + + DFK ++E + V + I + KN + + G + ++ +
Sbjct: 63 HSEKFQISFPKKPEVDFKTLIERISKTVDDESASILPAYDKNPNITYISGTASFISDKVI 122
Query: 152 EVHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
V+GE+ + K I IASG+ + PG+ +TS L +PK M+VIG
Sbjct: 123 TVNGEQ----LTAKRIFIASGARPAIPDIPGLA--GTPFMTSRETLRRTDLPKSMIVIGG 176
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
G I LELG Y G++VT + + D ++ ++I +K+ L T + +
Sbjct: 177 GFIALELGFAYSSFGSEVTFLVRNRMLKNE--DKDIVDEFERIFTKEH-NVLLHTNIHKI 233
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
+ + V EA G +L + +L++ G RP T L L I D G I VN
Sbjct: 234 EYNKNLFYV--EAISQGKTILLQSEALLVATGIRPNTDLLNLQNTNIQTDKNGYIVVNEY 291
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI----KGMPVHFNYDAIPSVIYTSPE 385
+TT PG+YA+GD+ H EG + K P+ Y +P ++T P+
Sbjct: 292 LETTSPGVYALGDITGKYFYRHSVNFEGEFLFRTLYQEKKRTPIE--YPPVPHAVFTHPQ 349
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGP 445
+ VGKTEE+L +EG Y K + A++ GFVK+L DK + +LG H+IG
Sbjct: 350 IAKVGKTEEELIQEGIDYVAAKNSYSASATGMARLSDSGFVKILIDKKSKKVLGAHVIGD 409
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
LI+ +L +D+ ++ + HP E R A
Sbjct: 410 EASNLIHLFILLMTMKGTLDDLLKMIYVHPALPEIARNA 448
>UniRef50_Q1GLP7 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=17;
Alphaproteobacteria|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Silicibacter sp.
(strain TM1040)
Length = 501
Score = 213 bits (520), Expect = 9e-54
Identities = 152/471 (32%), Positives = 230/471 (48%), Gaps = 16/471 (3%)
Query: 30 HDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNS-HLY 88
+D DL+VIGSGP G AAI+AA+L +V+ +++ LGG ++ G +PSK L +L
Sbjct: 8 YDYDLIVIGSGPSGRTAAIQAAKLKRRVLVIDRKDRLGGVSVHTGTVPSKTLRETVLNLT 67
Query: 89 HMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAML---FQKNKVNLVKGVGTI 145
+ F R D K + KA L + +L F +N V+++ G+
Sbjct: 68 GWRERSFYGRAYRVK----DQIKAEDLKARLHMTLDHEVDVLEHQFNRNHVDMLAGMAHF 123
Query: 146 VAPNKVEVHGEKGVET-VNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKM 204
PN+VEV E G T V + LIA+G+ V F+ ++ L + +P+ +
Sbjct: 124 TGPNEVEVEVEAGDTTRVTGEKFLIATGTRTYRPDSVPFNGTTVVDGDEFLEMAEIPRSL 183
Query: 205 LVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGT 264
+V+GAGVIG+E +++ L VT IE + ID + + + + G+ +LG+
Sbjct: 184 IVVGAGVIGVEYATMFSALDVRVTLIEPRDTFLDF-IDRTLIQEFTHQIRENGVDLRLGS 242
Query: 265 KVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRI 324
+ ++ EGS I+V +E + E+L L + GR T L L VG+ D RGR+
Sbjct: 243 AIESIEDEGSHIEVTLENGRHVRGEML-----LFAAGRMGNTDRLNLKAVGLETDHRGRL 297
Query: 325 PVNNK-FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTS 383
V K +QT V IYA GDVI P LA + +G V +P P IY+
Sbjct: 298 EVERKTYQTKVSHIYATGDVIGHPSLASTSLQQGRVAACHAMDVPTVPESPWFPYGIYSV 357
Query: 384 PEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHII 443
PE+ G +EE+LK+ G Y+VG F SR G G +K+L T +LG I+
Sbjct: 358 PEMSTCGMSEEELKERGVPYEVGIARFRETSRGHIMGLEHGMLKMLFSLKTRRVLGVQIV 417
Query: 444 GPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPI 494
G G ELI+ A + + +PT AEA + A L A++ PI
Sbjct: 418 GEGATELIHIAQAVLNLKGTVDYFVQNTFNYPTLAEAYKIAGLDAFNRMPI 468
>UniRef50_A3TPL4 Cluster: Pyridine nucleotide-disulphide
oxidoreductase; n=1; Janibacter sp. HTCC2649|Rep:
Pyridine nucleotide-disulphide oxidoreductase -
Janibacter sp. HTCC2649
Length = 453
Score = 213 bits (520), Expect = 9e-54
Identities = 147/470 (31%), Positives = 240/470 (51%), Gaps = 38/470 (8%)
Query: 27 ATTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEK-DPTLGGTCLNVGCIPSKALLHNS 85
ATT DA ++IG G GG A A G +V+ VE+ D GGTC+N+GC+P+KAL+ ++
Sbjct: 4 ATTFDA--IIIGWGKGGKTLAAFLASRGDRVLMVEQSDRMFGGTCINIGCVPTKALVESA 61
Query: 86 -HLYHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGG--IAMLFQKNKVNLVKGV 142
H +A D + + +E K NA+ L G +M+ ++ G
Sbjct: 62 NHPSLVADADVR------------YLNAVERK-NALTSLLRGKNFSMVDSHESATVLTGR 108
Query: 143 GTIVAPNKVEVHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESV 200
V P+++EV + I+I +GS V P PG+ D +++TST + +
Sbjct: 109 ARFVGPHEIEVSASNERVRATSDRIIINTGSVPVVPPIPGL--DGPRVVTSTELIDETDL 166
Query: 201 PKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKF 260
P++++VIGAG IGLEL Y+ GA+VT ++ + D +VA ++++L G+ F
Sbjct: 167 PRRLVVIGAGAIGLELAGAYRTFGAEVTVVDSADRLLPRE-DDDVADAVRQVLEADGISF 225
Query: 261 KLGTKVLGVKKE--GSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIAL 318
G V V GS + +D G++ + + D VL+++GRRP T LGL+ GI
Sbjct: 226 IFGATVDHVDDTAAGSVVHLD------GDRTI-EADRVLVAVGRRPATDDLGLEAAGIET 278
Query: 319 DDRGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYD--AI 376
DRG + V+ + +T+V G++A+GDV GP + + D+ + + + G D A+
Sbjct: 279 TDRGAVLVDAQLRTSVEGVWAVGDVNGGPQFTYVSLDDNRIVKDQLVGQGARRTTDRVAV 338
Query: 377 PSVIYTSPEVGWVGKTEEDLKKEGRAYKVGK---FPFLANSRAKTNGETEGFVKVLSDKT 433
P+ + +P + VG +E + + G KV + A RA+ GET G +K++ D
Sbjct: 339 PATTFITPPLARVGLSESEARDAGHTVKVAQKNIDTIAAMPRARIVGETRGLIKIVVDAE 398
Query: 434 TDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
+D+ILG + E+IN LA + A ++ HP+ EAL E
Sbjct: 399 SDLILGATVFCVDSQEIINLVALAMRHDVTAAELRDSIWTHPSSTEALNE 448
>UniRef50_A3H831 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=2;
Thermoproteaceae|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Caldivirga
maquilingensis IC-167
Length = 490
Score = 212 bits (518), Expect = 2e-53
Identities = 148/462 (32%), Positives = 230/462 (49%), Gaps = 18/462 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+VVIG G GGY A + ++ G V+ V+ LGG CL GCIPSKA+ + +L +
Sbjct: 31 DVVVIGGGGGGYHGAFELSKGGYSVLLVDDKGNLGGNCLYEGCIPSKAVSVSLYLLEKLR 90
Query: 93 HDFKQRGIETGE-VTFDFKKMMEYKANA-VKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
G E V ++ ++++K N I + + V+ VKG+ ++ ++
Sbjct: 91 GILSSVGNNDAEKVRLLWENLIDHKDNVQYLRYLQHIREIKEHGNVDFVKGIARVIDNHR 150
Query: 151 VEVHGEKGV--ETVNTKNILIASGSEVT--PFPG--VTFDEKQIITSTGALSLESVPKKM 204
V V G V + +L+A+GS P PG +T +++ L +P +
Sbjct: 151 VIVESIDGSWRREVEGRYLLVATGSLPIKIPVPGADLTLGSQELFGYR--TKLRRIPSDV 208
Query: 205 LVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGT 264
+VIG G IG+E+ SV LG T +E L I G D + +++ L +G+ +
Sbjct: 209 VVIGGGYIGVEVASVLSGLGVKTTIVEMLPRILS-GWDSGIVSMIEEKLRSRGVAILTNS 267
Query: 265 KVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRI 324
+V G+K+EG V+ G V +V++ ++GRR + L ++GI DR +
Sbjct: 268 RVTGIKEEGGQKIVEYSRPDGSVGYVTGSEVIM-AVGRRANVEDLS--QLGIV--DRNHV 322
Query: 325 PVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIK-GMPV-HFNYDAIPSVIYT 382
VN+ T VP +YA GDVI ML H A E +V I G + N++ IP I+T
Sbjct: 323 DVNSAMATKVPNVYAAGDVIGRYMLYHAAVKESVVASWNIMMGRQIFEVNFNTIPMTIFT 382
Query: 383 SPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHI 442
PE VG +EE K G Y V ++P +S A+ G +G+VK++ +K T I+G I
Sbjct: 383 EPEAAMVGLSEEAAKARGINYTVVQYPLSDDSYAQIIGVRDGWVKLIIEKETQRIIGGVI 442
Query: 443 IGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
G +INE LA A +D+A + HAHPT E++ A
Sbjct: 443 YGEAASMMINEVALAIAVNARVKDIALLAHAHPTIFESIDRA 484
>UniRef50_Q184K0 Cluster: Putative pyridine-nucleotide-disulfide
oxidoreductase; n=2; Clostridium difficile|Rep: Putative
pyridine-nucleotide-disulfide oxidoreductase -
Clostridium difficile (strain 630)
Length = 462
Score = 212 bits (517), Expect = 2e-53
Identities = 147/461 (31%), Positives = 236/461 (51%), Gaps = 24/461 (5%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTL-GGTCLNVGCIPSKALLHNSHLYHMA 91
D ++IG G GG A A G+KV +EK + GGTC+NV CIP+K+L ++++
Sbjct: 6 DAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTCVNVACIPTKSLENSAN----- 60
Query: 92 KHDFKQRGIET-GEVTFDFKKMMEYKANAVKGLT-GGIAMLFQKNKVNLVKGVGTIVAPN 149
K + I + EV +++K ++ K + L L V + G+GT +
Sbjct: 61 --SVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSNENVTIFTGMGTFIDEK 118
Query: 150 KVEVHGEKGVETVNTKNILIASGSEVTPF-PGVT-FDEKQII-TSTGALSLESVPKKMLV 206
V+V E + + NI I +GS PF P + + K I+ S ++L ++PKKM +
Sbjct: 119 TVQVKTENEIYELVADNIFINTGSR--PFIPNIKGIENKNIVYDSESLMNLRTLPKKMTI 176
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGV--GIDGEVAKTLQKILSKQGMKFKLGT 264
IGAG IGLE +Y GA+VT L S G+ D E ++ + K+L+K+ +K
Sbjct: 177 IGAGFIGLEFAGIYSSFGAEVT---ILNSNNGILPNEDVEDSEEIIKLLAKRNVKIVNNA 233
Query: 265 KVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRI 324
+ +K+ V+ E G +KE L +++L++ GR+ T+GLGL+ GI L++RG I
Sbjct: 234 NIKEIKEVSELAIVEYEV-DGKSKE-LTSNMILVATGRKANTEGLGLENAGIELNERGFI 291
Query: 325 PVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDA--IPSVIYT 382
V+ +T I+AIGD+ GP + + D+ + + + G D IP+ I+
Sbjct: 292 KVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGDKTRTTNDRKNIPNSIFI 351
Query: 383 SPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHI 442
SP VG + K++G V K P A RAK G+ +GF+K++ DK ++ ILG +
Sbjct: 352 SPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKADGFIKIVIDKKSNKILGASM 411
Query: 443 IGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
I E+I+ LA + + +AHPT EAL +
Sbjct: 412 ICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEALND 452
>UniRef50_A7CW98 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=1; Opitutaceae
bacterium TAV2|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Opitutaceae
bacterium TAV2
Length = 474
Score = 212 bits (517), Expect = 2e-53
Identities = 144/463 (31%), Positives = 225/463 (48%), Gaps = 17/463 (3%)
Query: 29 THDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLY 88
TH DL+VIG G G+ AA A+ LG V V+ P LGG C+ GC+PSK LLH + +
Sbjct: 6 THIHDLIVIGGGSAGFNAARVASGLGKNVAIVDGAPDLGGLCILRGCMPSKTLLHAADVL 65
Query: 89 HMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAP 148
H A+H K GI + D + + +K + + Q + L + +
Sbjct: 66 HHARHGGK-LGIRAPGASIDMRALHRWKKKVIGEFSDYRVQAMQSGRYTLHRSHARFIDS 124
Query: 149 NKVEVHGEKGVETVNTKNILIASGSEVT--PFPGVTFDEKQIITSTGALSLESVPKKMLV 206
+ +++ + G +++ + ILIA+GS V+ P PG+ D+ TS L L+ VP+ ++V
Sbjct: 125 HTLKL--DNG-DSLRGQKILIATGSRVSVPPIPGL--DDTPHWTSDDVLDLDYVPESVIV 179
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
+G G++ EL R+G+ VT I+ + E A + + +G++ GT++
Sbjct: 180 LGGGIVACELAQFLNRIGSKVTLIQRSPHLLREH-SPEAADVVAQAFRDEGIRLHTGTRI 238
Query: 267 LGVKKE-GSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIP 325
L V E G ++V E + ++GR P T GL LD G+ALD+RGRI
Sbjct: 239 LSVSGENGRQVRVVFEHPHLNKTHTCRARHLFNALGREPATDGLNLDAAGVALDERGRIR 298
Query: 326 VNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVE---GIK---GMPVH-FNYDAIPS 378
VN QTT P IYA GDV + H A +G + G + G P+ + +
Sbjct: 299 VNRWQQTTQPHIYAGGDVCGPHEIVHLAVAQGELAARHAFGARLPSGKPLKPIDESLLLG 358
Query: 379 VIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVIL 438
V++T P + +G E L+K G+ + +PF + ++ T G VKV++D +L
Sbjct: 359 VVFTDPALATIGWQEHLLRKRGQPFVAASYPFNDHGKSIVMDATYGHVKVIADPVRGRLL 418
Query: 439 GTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
G I+G GELI+ A D+ R HPT AE +
Sbjct: 419 GAEIVGRDAGELIHAFSGPLAMRATVHDLLRAPWYHPTLAEII 461
>UniRef50_Q5V791 Cluster: Mercuric reductase; n=1; Haloarcula
marismortui|Rep: Mercuric reductase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 484
Score = 212 bits (517), Expect = 2e-53
Identities = 139/466 (29%), Positives = 224/466 (48%), Gaps = 11/466 (2%)
Query: 29 THDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLY 88
T D DLV++G G + A +A++ + V +GGTC+NVGC+PSK LL +
Sbjct: 4 TSDYDLVILGGGAAAFAAITEASRRDLSTAMVNTGLPIGGTCVNVGCVPSKHLLAVAESG 63
Query: 89 HMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTG-GIAMLFQKNKVNLVKGVGTIVA 147
A + E T D+ + V+ + + ++++ +G G +V
Sbjct: 64 AAASENPFDAVRYPEEPTVDWAAALNDTDELVERFRQENYVDIAEHFEIDIYEGYGQLVD 123
Query: 148 PNKVEV-HGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLV 206
+EV G + + L+A+GS P + TS L +P+ +L+
Sbjct: 124 DTTIEVVDGADEGARITGEKALVATGSSPWAPPIDGLYDVDYYTSETILEERDLPESILM 183
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
+G G I LE G + R+G DVT ++ + ++G++ + +Q+ ++G++ G
Sbjct: 184 LGGGYIALEWGQILHRVGIDVTVLQRSDRVLS-DMEGQLGREMQRAFEEEGIEVITGNDF 242
Query: 267 LGVKK-------EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALD 319
V+ E V VE G++ + D + ++ G +P ++G+GL+ VGI +
Sbjct: 243 QRVRTLAADGGAEAIQSGVAVETTIDGDERTVTGDALFVATGVQPNSEGIGLETVGIETN 302
Query: 320 DRGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMP-VHFNYDAIPS 378
G I V+ FQTT P IYA GDVI P L A EG V+ G V +YDA+P+
Sbjct: 303 PDGTIRVDEYFQTTNPDIYAAGDVIGEPELETVAAKEGNHAVKNAFGNEGVSIDYDAVPA 362
Query: 379 VIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVIL 438
V++TSPEV VG TE + E RAK T+G V+V+ TD I+
Sbjct: 363 VVFTSPEVAAVGTTELEYMDEHGTCSCRTVQMADVPRAKAVENTDGLVQVVKHHETDEIV 422
Query: 439 GTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
G H++GP ++I EA LA +G +D+ H PT +EA ++A
Sbjct: 423 GVHMVGPRAADMIMEATLAVTFGLTVDDIIDTVHPFPTFSEAFKQA 468
>UniRef50_Q1GTU0 Cluster: Glutathione reductase; n=12; Bacteria|Rep:
Glutathione reductase - Sphingopyxis alaskensis
(Sphingomonas alaskensis)
Length = 448
Score = 210 bits (514), Expect = 5e-53
Identities = 142/455 (31%), Positives = 225/455 (49%), Gaps = 19/455 (4%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
D DL VIG+G GG A+ AA G +V +V ++ +GGTC+ GC+P K L++ +H
Sbjct: 5 DFDLFVIGAGSGGVRASRIAASHGARV-AVAEEHRVGGTCVIRGCVPKKLLVYGAHFAED 63
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
K D ++ G E + FD+ + + V L G +KV + K T+VAP
Sbjct: 64 LK-DARKFGWEVPDCRFDWDVLRDNVLAEVDRLEGLYGQTLDNHKVRVFKTRATVVAPQT 122
Query: 151 VEVHGEKGVETVNTKNILIASGS--EVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
V + G E + + ILIA+G V FPG + ITS LE++P+++++ G
Sbjct: 123 VRL--ADGQE-LTAERILIATGGWPHVPDFPG----SEHAITSNEVFHLETLPRRVVIAG 175
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
G I E ++ G+ VT + +I G D ++ L +I +G+ FK
Sbjct: 176 GGYIANEFAGIFNEFGSKVTIVNRGDTILR-GYDEQIRDRLLQISMTKGIDFKFNAPFEK 234
Query: 269 VKK-EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVN 327
++K + T+ + + G E + D VL++ GR P TKGLGLD+VG+ LD G I V+
Sbjct: 235 IEKNDDGTLTIYL-----GGCEPIVADAVLVATGRVPNTKGLGLDEVGVDLDPTGAIRVD 289
Query: 328 NKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPEV 386
Q++VP IY +GDV + L A EG + + G P +Y +PS +++ P +
Sbjct: 290 EHNQSSVPSIYGVGDVTNRIQLTPVAIREGQAFADSVFGGHPTVVDYANVPSAVFSHPPI 349
Query: 387 GWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPG 446
G VG TE + + + + +V F A K++ + TD ++G H+IGP
Sbjct: 350 GAVGMTEAEARNKLGSVRVYTSDFRAMKNVLAGRNERALYKMIVNAATDQVVGLHMIGPD 409
Query: 447 GGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
E++ A +A + G D HP+ AE L
Sbjct: 410 APEILQAAAIAVKAGLTKADFDATVALHPSMAEEL 444
>UniRef50_Q74DK1 Cluster: Mercuric reductase; n=4; Bacteria|Rep:
Mercuric reductase - Geobacter sulfurreducens
Length = 505
Score = 210 bits (513), Expect = 6e-53
Identities = 145/456 (31%), Positives = 218/456 (47%), Gaps = 16/456 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DLVV+G+G G V A AA LG +V VE+ LGG CLN GC+PSKAL+ + H A
Sbjct: 32 DLVVVGAGTAGLVCAAGAAGLGARVALVERH-RLGGDCLNYGCVPSKALIRAARAAHDAG 90
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTG--GIAMLFQKNKVNLVKGVGTIVAPNK 150
+ D +ME + ++ G A+ F+ V++ G G+ ++ N
Sbjct: 91 NGAPFGVTGCHGTGVDGAAVME-RMRRLRAEIGRHDAAVRFRDLGVHVFFGQGSFISRNA 149
Query: 151 VEVHGEKGVETVNTKNILIASGSEVT--PFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
+EV G + +N + + +G+ P PG+ E +T+ SL ++P ++ VIG
Sbjct: 150 LEVDGRR----LNFVHAAVCTGARAAAPPVPGLA--EAGYLTNETIFSLATLPARLAVIG 203
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
G IG EL RLG+ VT IE I D + A ++ L + + F V+G
Sbjct: 204 GGPIGCELAQAAARLGSSVTVIEAAPEILPRE-DTDAAALVRHALERDRVSFLTAAAVVG 262
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
V++ + V +G + D +L+ GR P +GLGL++ GI D + VN+
Sbjct: 263 VERRSGARTLIVR--QGDQSHEVTADEILVGAGRTPNIEGLGLERAGIVADPLRGVRVND 320
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEG-IVCVEGIKGMPVHFNYDAIPSVIYTSPEVG 387
+ +T P +YA GD+ H A+ IV + G F+ IP YT PEV
Sbjct: 321 RLRTDNPRVYAAGDICSPYRFTHAADAMARIVVANALFGARQRFSTQIIPWCTYTDPEVA 380
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG E + + G A P RA +GE EGF +V + TD I+G I+
Sbjct: 381 HVGLYEREAGERGLAVDTLTVPLTEVDRALLDGEDEGFARVHLKRGTDRIVGATIVARHA 440
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
GE++NE LA G + R H +PT AEA+++
Sbjct: 441 GEMLNELTLAMSAGLGLSAIGRSIHPYPTQAEAIKK 476
>UniRef50_Q41CB3 Cluster: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase:Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
precursor; n=1; Exiguobacterium sibiricum 255-15|Rep:
FAD-dependent pyridine nucleotide-disulphide
oxidoreductase:Pyridine nucleotide-disulphide
oxidoreductase dimerisation region precursor -
Exiguobacterium sibiricum 255-15
Length = 475
Score = 210 bits (513), Expect = 6e-53
Identities = 146/454 (32%), Positives = 226/454 (49%), Gaps = 15/454 (3%)
Query: 34 LVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAKH 93
LVVIG G G A AA LG V +EK LGG CL+ GC+PSKAL+ +H H+ K
Sbjct: 6 LVVIGGGAAGMTIAAGAASLGAHVALIEKHTHLGGDCLHYGCVPSKALIEAAHDVHVMKQ 65
Query: 94 DFKQRGIE-TGEVTFD-FKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
+ + GE + K ++ N ++ G F+ V++ G + ++ N+V
Sbjct: 66 TAAKYNVTLNGEAVYSKTKASVDRARNIIQSHDG--TKRFKDLGVDVYIGEASFLSANEV 123
Query: 152 EVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGV 211
EV G + V + I++GS+ P D +T+ P+++LVIG G
Sbjct: 124 EVAG----QLVVGEKFAISTGSQPIIPPIEGLDTIPYLTNETIFEQTERPERLLVIGGGA 179
Query: 212 IGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKK 271
IGLEL Y LG +VT IE S+ D + + LQ+ + +Q + L T V V+K
Sbjct: 180 IGLELSQAYAHLGTEVTVIEGAKSLMPKE-DRSMVEVLQRQI-EQELTLHLDTTVTSVRK 237
Query: 272 EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQ 331
I+V V+ G V++ D VL+++GR+P L LD+ G+ + ++G + V+ +
Sbjct: 238 AAKGIEVTVKT--GEESRVIETDAVLVAVGRKPRIDALRLDRAGVHV-EKGYVQVDGSLR 294
Query: 332 TTVPGIYAIGDVIHGPMLAHKAEDEG-IVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVG 390
T I+A+GD I H A EG V + G+ +Y A+P V +T+PE+ +G
Sbjct: 295 TNQRHIFAVGDTIQSLPFTHVAGLEGKTVVTNALFGLRTKPDYRAVPWVTFTTPELFHLG 354
Query: 391 KTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGEL 450
TEE+ +++ KV + R NG TEG VK+++DK +I G H IG GE
Sbjct: 355 LTEEEARQKYSDIKVYETGLDEVDRFVINGRTEGHVKLIADKRGKLI-GAHAIGEQAGEW 413
Query: 451 INEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
+ E V A ++RV H +P A++ A
Sbjct: 414 MQEVVYAMARKDKVGQLSRVVHPYPIRGAAVQRA 447
>UniRef50_P96104 Cluster: Dihydrolipoyl transacetylase and lipoamide
dehydrogenase of the pyruvate dehydrogenase complex;
n=1; Acidithiobacillus ferrooxidans|Rep: Dihydrolipoyl
transacetylase and lipoamide dehydrogenase of the
pyruvate dehydrogenase complex - Thiobacillus
ferrooxidans (Acidithiobacillus ferrooxidans)
Length = 978
Score = 210 bits (513), Expect = 6e-53
Identities = 143/459 (31%), Positives = 222/459 (48%), Gaps = 11/459 (2%)
Query: 30 HDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYH 89
+D ++VIG+GPGG A + A+ G++V V P G CL GCIPSKA +
Sbjct: 510 YDVQVLVIGAGPGGEDCARELAENGIRVAMVNDAPA-GRECLWRGCIPSKAWRAAADRIR 568
Query: 90 MAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKG-VGTIVAP 148
+ GI G D+ ++ +++ ++ G + N G +
Sbjct: 569 PGAR--RAMGITLGTPRLDWAQLEQHRRGILQ-TRGRNGPENRSGCENSGAGRLCRFTGD 625
Query: 149 NKVEVHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQ--IITSTGALSLESVPKKM 204
+ VE+ G K T+ +IA+G+ V P PG+ K +TS +L+ P ++
Sbjct: 626 HSVEISG-KDARTLTFGACVIATGAPAFVPPIPGIQDALKSGAAVTSDTVWNLKQPPARL 684
Query: 205 LVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGT 264
VIGAG IG+E+ ++ GA+V +E L ++ EVA+ L K ++ ++ ++ T
Sbjct: 685 CVIGAGAIGMEMAQMFHDFGAEVRVLEALPR-PVAEMEKEVAEQLMKAIAHNSLRLQVLT 743
Query: 265 KVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRI 324
V + G+T V G CD++L++ G+RP T GL L G+AL DR I
Sbjct: 744 GVKVTEVAGATRPVGGALQSGDEAANYACDLLLVATGKRPDTSGLNLAAAGVALGDRAVI 803
Query: 325 PVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSP 384
V+ +T VP IYA+GDVI G MLAH A +G V + G + V +T P
Sbjct: 804 AVDASGRTNVPHIYAVGDVIGGYMLAHTAGQQGRVAAASLLGHSARYEAAKDCGVTFTRP 863
Query: 385 EVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 444
+ +VG + E + EG K P +++A GET+G +K+++DK + I+G H +
Sbjct: 864 QCAFVGLSLEQARAEGIDAVEVKVPLSIDAKAMMTGETDGLIKIVADKISHRIVGVHFLA 923
Query: 445 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
L+ EAV+ G E VA H HPT E E
Sbjct: 924 DHADTLVGEAVMMVSAGLTLEQVAGAIHPHPTQTELFGE 962
>UniRef50_Q6SKC7 Cluster: Dihydrolipoamide dehydrogenase-like
protein; n=23; Bacteria|Rep: Dihydrolipoamide
dehydrogenase-like protein - Arthrobacter aurescens
Length = 627
Score = 209 bits (511), Expect = 1e-52
Identities = 130/330 (39%), Positives = 179/330 (54%), Gaps = 21/330 (6%)
Query: 135 KVNLVKGVGTIVAPNKVEVHGEKGV--ETVNTKNIL------IASGSEVTPFPGVTFDEK 186
KV V+G G V N +EV G E TK ++ IA+GS+ P + D +
Sbjct: 6 KVTTVRGYGAFVGANHLEVEETTGTGQEKTGTKKVIAFKRAIIAAGSQAVRLPFMPNDPR 65
Query: 187 QIITSTGALSLESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVA 246
++ STGAL+L VPK+ML++G G+IGLE+G+VY LGA + +E + + G D ++
Sbjct: 66 -VVDSTGALALSGVPKRMLILGGGIIGLEMGTVYSTLGARLDVVEMMDGLMQ-GADRDLV 123
Query: 247 KTLQKILSKQGMKFKLGTKVLGVKKEGSTIKVDVEAAKGGNK--EVLDCDVVLISIGRRP 304
K QK+ +K+ L TK +G + IKV A+ G E D+VL ++GR P
Sbjct: 124 KIWQKMNAKRFDNIMLKTKTVGAEATPEGIKVTFAPAEEGGTTPEPQVYDLVLQAVGRTP 183
Query: 305 YTKGLGLDKVGIALDDRGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI 364
K + +K G+A+ DRG I V+ + +T VP I+AIGD++ PMLAHKA E V E I
Sbjct: 184 NGKKIAAEKAGVAVTDRGFINVDIQMRTNVPHIFAIGDIVGQPMLAHKAVHEAHVAAEVI 243
Query: 365 KG--------MPVHFNYDAIPSVIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRA 416
G FN IPSV YT PEV WVG TE+ K +G K G FP+ A+ RA
Sbjct: 244 AGELQGNKELASAAFNARVIPSVAYTDPEVAWVGLTEDQAKAQGIKVKKGLFPWTASGRA 303
Query: 417 KTNGETEGFVKVLSDKTTDVILGTHIIGPG 446
NG EGF K+L D + + I PG
Sbjct: 304 IANGRDEGFTKLLFDDSPEAAT-PRISSPG 332
>UniRef50_A5FUY9 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region precursor; n=1;
Acidiphilium cryptum JF-5|Rep: Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
precursor - Acidiphilium cryptum (strain JF-5)
Length = 705
Score = 209 bits (510), Expect = 1e-52
Identities = 157/485 (32%), Positives = 238/485 (49%), Gaps = 36/485 (7%)
Query: 6 LKLASPTFRSGSLVR--IATRQYATTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKD 63
L LA+P R R A + D +LVVIG+G GG VAA A+ + KV VE
Sbjct: 221 LPLAAPRLRDALATRRLYARFRRPKRFDRNLVVIGAGAGGLVAAYVASAVKAKVTLVEAG 280
Query: 64 PTLGGTCLNVGCIPSKALLHNSHLYHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGL 123
+GG CLN GC+PSKALLH + G+ DF+ + A+ G+
Sbjct: 281 E-MGGDCLNSGCVPSKALLHAAR---------------AGK---DFRAAIADVRAAIAGI 321
Query: 124 TGGIAML-FQKNKVNLVKGVGTIVAPNKVEVHGEKGVETVNTKNILIASGSE--VTPFPG 180
++ ++ V + +G I +P V V G + T+ I+IA+G+E V P PG
Sbjct: 322 APHDSVARYEGLGVEVRRGRAVIESPWCVAVDGVP----ITTRAIVIAAGAEPFVPPIPG 377
Query: 181 VTFDEKQIITSTGALSLESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVG 240
+ E TS +E +P++++++G G IG E+ + RLG+ VT +E + V
Sbjct: 378 LA--EAPHATSETLWDIEDLPRRLVILGGGPIGCEMAQAFARLGSAVTLVEMSERLL-VR 434
Query: 241 IDGEVAKTLQKILSKQGMKFKLGTKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISI 300
D EV+ + L++ G+ + G + V + + + AA G L D +L++I
Sbjct: 435 EDDEVSAAMAAALARDGVAIRTGHRAEAVTRTEAGFAL--VAASGVQTIELPFDRLLVAI 492
Query: 301 GRRPYTKGLGLDKVGIALDDRGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVC 360
GRRP G GL+ +GI L I ++ +T P I+A GDV H A +G
Sbjct: 493 GRRPRVSGYGLEALGIPLTPARTIETDDGLRTLYPNIFACGDVAGPYQFTHMAGYQGGYA 552
Query: 361 VEGIKGMPV-HF--NYDAIPSVIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAK 417
G P F +Y A+P+V YTSPE+ VG + G ++ ++ F RA
Sbjct: 553 ALGALFAPFWRFRPSYRAVPAVTYTSPEIARVGLNAREAAARGIEAEITRYDFAELDRAI 612
Query: 418 TNGETEGFVKVLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTC 477
G+TEGFV VL+ K +D ILG I+GP GEL+ LA ++G + + +PT
Sbjct: 613 AEGDTEGFVTVLTRKGSDRILGATIVGPQAGELLTGFTLAMQHGLGLKKLMGTIFPYPTR 672
Query: 478 AEALR 482
+EA+R
Sbjct: 673 SEAIR 677
>UniRef50_Q0AAN2 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region precursor; n=1;
Alkalilimnicola ehrlichei MLHE-1|Rep: Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
precursor - Alkalilimnicola ehrlichei (strain MLHE-1)
Length = 473
Score = 208 bits (509), Expect = 2e-52
Identities = 145/463 (31%), Positives = 232/463 (50%), Gaps = 20/463 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL++IG G GG V A A QLG+K V ++ LGG CL+ GC+PSK L+ ++ + + +
Sbjct: 4 DLIIIGGGVGGLVTASVAGQLGVKTVLIDAGANLGGDCLHYGCVPSKTLIRSAEVAALTR 63
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGL-TGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
+ G++ D +M+ + + F+ V++ G + + V
Sbjct: 64 R-AGEFGLQAELGPVDLGAVMDRVRQVIDQIQVHDDPDRFRGYGVDVRFGHARFLDRDTV 122
Query: 152 EVHGEKGVETVNTKNILIASGS--EVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
V GE+ + + +IA+GS V P PG+ E T+ L ++P+++ V+G
Sbjct: 123 SVDGER----LQARRFVIATGSAPAVPPVPGLA--EAGFHTNETIFQLRTLPRRLAVMGG 176
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
G IG+EL + RLG+ VT +E I D E A L+ +L +G+ T V V
Sbjct: 177 GPIGIELAQAFSRLGSQVTVVEMAAQILPRD-DAEQAAELRSVLDAEGITVHTATTVERV 235
Query: 270 KK-EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
++ EG T + G + + D +L++ GR+P LGL+ G+A RG I V+
Sbjct: 236 EQSEGIT---RLACRNGESHWTVTADALLLAAGRKP-NLDLGLEAAGVAYGPRG-IRVDR 290
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAE-DEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVG 387
+ +++V IYA+GD H AE GIV + +P +Y +P V YT+PE+
Sbjct: 291 RQRSSVRHIYAVGDCCGPYPFTHMAEYQAGIVIANALFRIPKKVDYRVVPWVTYTAPELA 350
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG TE++ + +V +FPF RA GET G K++ + ++G ++GP
Sbjct: 351 TVGLTEDEARARNLKVEVLRFPFREVDRALAEGETAGQAKLIVRRGR--LVGASVLGPHA 408
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYS 490
GELI+EAVLA + +A HA+PT A+ R A Y+
Sbjct: 409 GELIHEAVLAIQARLRVGTLAAAIHAYPTLAQVFRRAVNTRYT 451
>UniRef50_A4BJ37 Cluster: Mercuric reductase; n=2; unclassified
Gammaproteobacteria|Rep: Mercuric reductase - Reinekea
sp. MED297
Length = 471
Score = 208 bits (509), Expect = 2e-52
Identities = 151/456 (33%), Positives = 231/456 (50%), Gaps = 26/456 (5%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL+VIGSG G AA A G KV+ +EKD GG C GC+PSK L++ + H A+
Sbjct: 5 DLIVIGSGAAGLTAAFTALGFGKKVLIIEKDRP-GGECTWSGCVPSKGLINRAKDVHTAR 63
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
F I+T + + + + E A+ + +K V+G V ++
Sbjct: 64 K-FADFDIDTRTLLQEVRGVSE----AI--YEHETPEVLEKAGAVFVQGEAAFVDAKTLK 116
Query: 153 VHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
V G ET K I+IA+GS V P PG+ DE +T+ E++PK ++V+GAG
Sbjct: 117 V----GQETYRGKRIIIATGSSPLVPPIPGL--DEVPFLTNESFFEQETLPKSIIVLGAG 170
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
IG+EL RLG +VT +E + I + A L++ L K+G++F+LGTK +GV+
Sbjct: 171 AIGMELSQAMNRLGVEVTVVEMMPEI-MFREEPAYAAILRERLVKEGVRFQLGTKAVGVE 229
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
K + I++ E K G ++ +L+++GR+ L LD GI DRG I V+
Sbjct: 230 KTETGIRLSTE--KDGESGQIEAQTLLLALGRKANIGSLNLDAAGIKA-DRG-IVVDAHL 285
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEG-IVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWV 389
QTT G+YA GDV L+H A + I + I + NY+ + +T PE
Sbjct: 286 QTTAKGVYACGDVAGPYQLSHMANFQAKIAAMNAILPINRKANYEHVAWTTFTDPEFARA 345
Query: 390 GKTEEDLKKE-GRAYKVGKFPFLAN-SRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
G TE + +++ G +V ++ RAKT G +K+++ K +LG HI+
Sbjct: 346 GMTEAEAREQYGDRIRVFEYDMADKLDRAKTKAGDIGHIKLITLKGR--VLGAHILAERA 403
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
GELI E + + G + V H +PT A+ALR+
Sbjct: 404 GELIAEVQVMKSLGMKFSKLQGVIHPYPTYADALRQ 439
>UniRef50_Q6LLT9 Cluster: Soluble pyridine nucleotide
transhydrogenase (EC 1.6.1.1) (STH) (NAD(P)(+)
transhydrogenase [B-specific]); n=88; cellular
organisms|Rep: Soluble pyridine nucleotide
transhydrogenase (EC 1.6.1.1) (STH) (NAD(P)(+)
transhydrogenase [B-specific]) - Photobacterium
profundum (Photobacterium sp. (strain SS9))
Length = 469
Score = 208 bits (508), Expect = 3e-52
Identities = 148/470 (31%), Positives = 234/470 (49%), Gaps = 15/470 (3%)
Query: 23 TRQYATTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALL 82
T+ TH D ++IGSGPGG AA+ + G+ V +E++ ++GG C + G IPSKAL
Sbjct: 2 TKNKKPTH-FDAIIIGSGPGGEGAAMGLTKAGLNVAVIERENSVGGGCTHWGTIPSKALR 60
Query: 83 HN-SHLYHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKG 141
H S + ++ + + TF +++ + + V T + +NK +L+ G
Sbjct: 61 HAVSRIIEYNQNPLYCKNNSSLHSTFS--QILGHAQDVVNKQTRMRQGFYDRNKCSLIFG 118
Query: 142 VGTIVAPNKVEV-HGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESV 200
+ + + V V + + + + +IA+GS GV FD ++ S L LE
Sbjct: 119 EASFIDAHTVRVKNADNSTDLYSADKFVIATGSRPYHPEGVDFDHSRVYDSDSILQLEHD 178
Query: 201 PKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKF 260
P+ +++ GAGVIG E S+++ LG V I + +D E++ +L L G
Sbjct: 179 PRHIIIYGAGVIGSEYASIFRGLGVKVDLINTRHRLLEF-LDNEISDSLSYHLWNSGAMI 237
Query: 261 KLGTKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDD 320
+ G ++ +I + +E+ G K DC +L + GR T L L+KVG+ D
Sbjct: 238 RNGETFEKIEGTDDSIILHLES---GKKMRADC--LLYANGRTGNTDKLNLNKVGLTPDS 292
Query: 321 RGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIK-GMPVHFNYDAIPSV 379
RG++ VN + T V +YA+GDVI P LA A D+G + I G D IP+
Sbjct: 293 RGQLAVNQNYCTDVDHVYAVGDVIGYPSLASAAYDQGRFVAQAITTGEAQGSLIDHIPTG 352
Query: 380 IYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILG 439
IYT PE+ VGKTE+ L + Y+VG+ F +RA+ G G +K+L + T ILG
Sbjct: 353 IYTIPEISSVGKTEQQLTADKVPYEVGRSQFKHLARAQIAGTEVGSLKILFHRETKEILG 412
Query: 440 THIIGPGGGELIN--EAVLAQE-YGAAAEDVARVCHAHPTCAEALREANL 486
H G E+I+ +A++ Q+ G + +PT AEA R A L
Sbjct: 413 IHCFGERAAEIIHIGQAIMEQKGDGNTIDYFVNTTFNYPTMAEAYRVAAL 462
>UniRef50_Q99MD6 Cluster: Thioredoxin and glutathione reductase;
n=9; Eukaryota|Rep: Thioredoxin and glutathione
reductase - Mus musculus (Mouse)
Length = 615
Score = 207 bits (506), Expect = 4e-52
Identities = 154/489 (31%), Positives = 243/489 (49%), Gaps = 27/489 (5%)
Query: 28 TTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVE---KDPT-----LGGTCLNVGCIPSK 79
+ HD DL++IG G GG A +AA LG KV+ ++ P LGGTC+NVGCIP K
Sbjct: 125 SAHDYDLIIIGGGSGGLSCAKEAANLGKKVMVLDFVVPSPQGTTWGLGGTCVNVGCIPKK 184
Query: 80 ALLHNSHLYHMAKHDFKQRGIE-TGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNL 138
L+H + L A D K+ G E +V +++ M E + + L G + ++ V
Sbjct: 185 -LMHQAALLGHALQDAKKYGWEYNQQVKHNWEAMTEAIQSHIGSLNWGYRVTLREKGVTY 243
Query: 139 VKGVGTIVAPNKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLE 198
V G V +K++ +KG ET T + + + E + G+ D++ ITS SL
Sbjct: 244 VNSFGEFVDLHKIKATNKKGQETFYTASKFVIATGERPRYLGIQGDKEYCITSDDLFSLP 303
Query: 199 SVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGM 258
P LV+GA +GLE LG DVT + + S+ G D E+A+ + L +QG+
Sbjct: 304 YCPGCTLVVGASYVGLECAGFLAGLGLDVTVM--VRSVLLRGFDQEMAEKVGSYLEQQGV 361
Query: 259 KF-KLGTKVLGVKKE-GSTIKVDVEAAKGGNKEVLD--CDVVLISIGRRPYTKGLGLDKV 314
KF + T +L + E G K+ V A E ++ + VL++IGR T+ +GL+K+
Sbjct: 362 KFQRKFTPILVQQLEKGLPGKLKVVAKSTEGPETVEGIYNTVLLAIGRDSCTRKIGLEKI 421
Query: 315 GIALDDR-GRIPVNNKFQTTVPGIYAIGDVIHG-PMLAHKAEDEGIVCVEGIKGMPVH-F 371
G+ ++++ G+IPVN+ QT VP +YAIGD++ G P L A G + + G+ +
Sbjct: 422 GVKINEKNGKIPVNDVEQTNVPHVYAIGDILDGKPELTPVAIQAGKLLARRLFGVSLEKC 481
Query: 372 NYDAIPSVIYTSPEVGWVGKTEED----LKKEG-RAYKVGKFPFLANSRAKTNGETEGFV 426
+Y IP+ ++T E G G +EE KKE Y +P + N +
Sbjct: 482 DYINIPTTVFTPLEYGCCGLSEEKAIEMYKKENLEVYHTLFWPLEWTVAGRDNNTC--YA 539
Query: 427 KVLSDK-TTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREAN 485
K++ +K + ++G H++GP GE+ A + G + + HPTC E
Sbjct: 540 KIICNKFDNERVVGFHLLGPNAGEITQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLE 599
Query: 486 LAAYSGKPI 494
+ SG I
Sbjct: 600 ITKSSGLDI 608
>UniRef50_A7HHC7 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=2;
Anaeromyxobacter|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Anaeromyxobacter
sp. Fw109-5
Length = 481
Score = 207 bits (505), Expect = 6e-52
Identities = 145/457 (31%), Positives = 215/457 (47%), Gaps = 14/457 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+VVIGSGP G AI+AA G KV +EK+ GG N G IPSKAL + L +
Sbjct: 5 DVVVIGSGPAGENGAIQAAFTGKKVALIEKEAVPGGASANTGTIPSKALRETA-LAILQA 63
Query: 93 HDFKQRGIE---TGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPN 149
GIE +G VT ++M K I + V +G+ + V P+
Sbjct: 64 RSRDAHGIELRISGTVTIP--ELMGRKGLVTAREHSRIRDALNRAGVEQFRGIASFVDPH 121
Query: 150 KVEVH-GEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
+ V + G + + IL+A G+ P D + S L L+ VP+ + V+G
Sbjct: 122 TIRVSIPDGGAQELQADIILLAPGTRPFHPPQYPIDNAHVYDSDSILLLDRVPRSLAVLG 181
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
GV G E S++ LG +V ++ + +D E++ L+ + G+ +
Sbjct: 182 GGVAGCEYASLFGALGVNVKLVDSKDRLL-TWLDAEMSHALEDVFRSSGIDLHQRNRAAR 240
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
+ + V +E GG + VL++ GR + L L G+ +RG + VN
Sbjct: 241 LDPGDKDVLVTLE--DGGR---MVAQKVLVASGRVGNVEALNLPAAGLEATERGLLKVNA 295
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAI-PSVIYTSPEVG 387
+FQT VP IYA GDV+ P LA + ++G V + G + +I P IYT PEV
Sbjct: 296 QFQTAVPHIYAAGDVVGFPGLASVSMEQGRVAMSHACGGILKQRVSSILPMGIYTIPEVS 355
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG TEE LK++GRAY VG+ N+RA GE GF+K+++D ILG H IGP
Sbjct: 356 SVGDTEETLKEQGRAYVVGRASLTENARANLIGEAVGFLKIIADAENGRILGVHCIGPHA 415
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
EL++ + + +PT EA + A
Sbjct: 416 SELVHTGAAVMAHQGDLQYFIEAVFNYPTLGEAYKYA 452
>UniRef50_Q311Y4 Cluster: Mercuric reductase, putative; n=4;
Deltaproteobacteria|Rep: Mercuric reductase, putative -
Desulfovibrio desulfuricans (strain G20)
Length = 486
Score = 206 bits (504), Expect = 8e-52
Identities = 132/454 (29%), Positives = 221/454 (48%), Gaps = 11/454 (2%)
Query: 30 HDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYH 89
+D D++VIG G G AAQLG+KV+ VE LGG CL+ GC+PSK LL + + H
Sbjct: 5 YDYDIIVIGGGAAGLTVTAGAAQLGVKVLLVESGHALGGDCLHYGCVPSKTLLRTAGVRH 64
Query: 90 MAKHDFKQRGIETGEV-TFDFKKMME--YKANAVKGLTGGIAMLFQKNKVNLVKGVGTIV 146
+ +H + G+ ++ DF ++ + + AV + F ++ G +
Sbjct: 65 LMRHAARY-GLPDAQLPPVDFAQVAQRISEVQAVIQQHDSVER-FTALGAEVLFGAASFA 122
Query: 147 APNKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLV 206
+ VE+ + V I+IA+GS + P E +T+ SL +P ++V
Sbjct: 123 DDHTVEIRSDDSVVRATGAKIVIATGSGASVPPLEGLKESGYLTNREIFSLPVLPASLIV 182
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
+G G + LE+ ++RLG +VT ++ + D ++A ++ L +G++ T++
Sbjct: 183 LGGGPVALEMAQAFRRLGTEVTVVQRSGQLLS-NEDADMADIVRLRLESEGVRVLTRTEI 241
Query: 267 LGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPV 326
+++ V V G++++L +L+++GR P+ GL L+ G+ RG + V
Sbjct: 242 QSIRRGAD--GVQVRLVHEGSEKLLSAAELLVALGRAPHVSGLTLENAGVVYSARG-VGV 298
Query: 327 NNKFQTTVPGIYAIGDVIHGPMLAHKAEDE-GIVCVEGIKGMPVHFNYDAIPSVIYTSPE 385
+ + +T VP IYA GDV + H A E GI+ + +P +Y +P +T PE
Sbjct: 299 DARMRTNVPHIYAAGDVTGRYLFTHAAGYEGGIIIANAVFRLPKKADYTNMPWCTFTDPE 358
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGP 445
+ VG E + G Y V F N RA G EG +K+L D + +LG I G
Sbjct: 359 LASVGLNERRAQAAGVDYTVRTELFSGNDRALAEGAPEGRIKMLLD-PREKVLGVQICGA 417
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAE 479
G GE+IN+ V Q + +A + +PT E
Sbjct: 418 GAGEIINQWVAVQAGKVSLSRIAGAVYPYPTLGE 451
>UniRef50_Q11NC3 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=7; cellular
organisms|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Mesorhizobium sp.
(strain BNC1)
Length = 211
Score = 206 bits (504), Expect = 8e-52
Identities = 100/206 (48%), Positives = 135/206 (65%), Gaps = 1/206 (0%)
Query: 286 GNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQTTVPGIYAIGDVIH 345
G E L+ D VL++IGRRP+T GLGL+ +G+ D +G + ++ +F+ +VPGI+AIGD +
Sbjct: 2 GGIETLEVDAVLVAIGRRPHTAGLGLEALGVRQDAKGFVEIDAQFRASVPGIHAIGDAVP 61
Query: 346 GPMLAHKAEDEGIVCVEGIKGMPVHF-NYDAIPSVIYTSPEVGWVGKTEEDLKKEGRAYK 404
GPMLAHKAE+ I C++ + G P +Y +P VIYT+PE+ VG +E+D GRA
Sbjct: 62 GPMLAHKAEEHAIACIDALAGRPNGAPDYGLVPGVIYTAPEIAGVGLSEDDASATGRAVL 121
Query: 405 VGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAA 464
VGK FLAN RA+ G T F KV++ T +LG HI+G G GEL+ E VLA G +
Sbjct: 122 VGKSSFLANGRARAIGATNDFAKVIACAETGKLLGAHILGHGAGELLQELVLALRLGVSL 181
Query: 465 EDVARVCHAHPTCAEALREANLAAYS 490
DVA HAHP EA++EA LAA S
Sbjct: 182 GDVAGTSHAHPGMGEAVKEACLAALS 207
>UniRef50_A6CF61 Cluster: Soluble pyridine nucleotide
transhydrogenase; n=1; Planctomyces maris DSM 8797|Rep:
Soluble pyridine nucleotide transhydrogenase -
Planctomyces maris DSM 8797
Length = 496
Score = 206 bits (503), Expect = 1e-51
Identities = 139/466 (29%), Positives = 233/466 (50%), Gaps = 23/466 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKD-PTLGGTCLNVGCIPSK----ALLHNSHL 87
D+V+IGSGP G AAI A++LG +V +E++ +GG CL+ G IPSK A+L+ +
Sbjct: 4 DIVIIGSGPAGQKAAIAASKLGKRVAIIERNFRGMGGVCLHKGTIPSKTMREAILYLTGY 63
Query: 88 YHM---AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGT 144
H +K ++R I ++ + E++ + ++N V + G
Sbjct: 64 RHRDVYSKWYRRKRRITMQDLRLKLADVAEHELEIIHDQ-------LERNGVEVYIGEAK 116
Query: 145 IVAPNKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKM 204
V+P++VEV E G + + IL+A+G++ + P + FD + I S + L+ +P+ M
Sbjct: 117 FVSPHEVEVDCETGRKQLYGDYILVATGTKPSRPPHIPFDGETIFDSDEIIDLKEIPRSM 176
Query: 205 LVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGT 264
+V+G GVIG+E ++ LG +VT ++ + D E+ L GM F++G
Sbjct: 177 IVVGGGVIGIEYAIMFATLGVEVTVLDGRERLLEF-CDREIIDALIHHARSLGMIFRMGE 235
Query: 265 KVLGVKK-EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGR 323
+V+G+++ S V E+ K L D VL ++GR L G+ D+RGR
Sbjct: 236 EVVGIERFSDSMAAVQTESGKR-----LVADSVLYTVGRVGDADELNFQAAGLEPDERGR 290
Query: 324 IPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTS 383
+ N + QT VP IY GD++ P LA + ++G + P +D +P ++T
Sbjct: 291 LWCNEEHQTWVPHIYGAGDIVGFPALASVSMEQGRRVICNAFNEPFE-AFDLMPYGLFTI 349
Query: 384 PEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHII 443
PE+ VGKTE+ L Y+VG + +R + +G+ +G +K+L + T ILG H I
Sbjct: 350 PEISMVGKTEQQLTDAHIPYEVGAARYREIARGQISGDRDGMLKILFHRETLKILGIHAI 409
Query: 444 GPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAY 489
G E+++ +G E +PT AE + A A+
Sbjct: 410 GEAATEIVHIGQTVMSFGGTIEYFRNAVFNYPTMAECYKVAAFDAF 455
>UniRef50_P73059 Cluster: Mercuric reductase; n=11; Bacteria|Rep:
Mercuric reductase - Synechocystis sp. (strain PCC 6803)
Length = 518
Score = 205 bits (501), Expect = 2e-51
Identities = 153/463 (33%), Positives = 228/463 (49%), Gaps = 23/463 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLG--MKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
DLVVIG+G G V A AA LG +KV +EK +GG CLN GCIPSKAL+ ++ + +
Sbjct: 40 DLVVIGAGTAGLVVAAGAAGLGIGLKVALIEKH-LMGGDCLNFGCIPSKALISSARVVGV 98
Query: 91 AKHDFKQRGIETGE-VTFDFKKMMEYKANAVKGLTG-GIAMLFQKNKVNLVKGVGTIVAP 148
++ GI+ + + DF +M G++ A F+ +++ G G V
Sbjct: 99 M-NNANSLGIKKPDSIEIDFPAVMARMRQIRTGISHHDSAQRFRDLGIDVFLGEGHFVRN 157
Query: 149 NKVEVHGEKGVETVNTKNILIASGSE-VTP-FPGVTFDEKQIITSTGALSLESVPKKMLV 206
N++EV G +N K +IA+G++ V P PG+ +E +T+ SL + P ++ V
Sbjct: 158 NQIEVGGA----ILNYKKAIIATGAKAVKPNIPGI--EEVGFLTNETVFSLTACPDRLGV 211
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
IG G IG EL +QRLGA VT + + D E A +Q+ L K G++ L K+
Sbjct: 212 IGGGPIGCELAQAFQRLGAQVTLFHRGSHLLNKE-DPEAAAIVQESLIKDGIELILNAKL 270
Query: 267 LGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPV 326
+ + A G+ + D +L+ GR P + L L+ VG+ D RG + V
Sbjct: 271 ERAELTDRGKVLHYRA--NGDSGTIVVDEILVGAGRAPNVEELNLEAVGVKFDRRG-VKV 327
Query: 327 NNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAI-----PSVIY 381
N+ QTT P IYA GD+ H A+ + ++ P + P V Y
Sbjct: 328 NDYLQTTSPQIYAAGDICMDWKFTHAADAAARIVIKNTLFSPFGLGRSKLSSLTMPWVTY 387
Query: 382 TSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTH 441
T PE+ VG E + YK+ K PF RA ETEGF+K++ +D ILG
Sbjct: 388 TDPEIAHVGLNETMAEALDIGYKIIKIPFSQVDRAIAADETEGFLKIIHVANSDEILGAT 447
Query: 442 IIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
I+ GE+I+E A +A V H +PT AEA+++A
Sbjct: 448 IVASHAGEMISEITTAIVNKIGLSKLAGVIHPYPTQAEAIKKA 490
>UniRef50_A6GLK6 Cluster: Glutathione reductase; n=1; Limnobacter
sp. MED105|Rep: Glutathione reductase - Limnobacter sp.
MED105
Length = 453
Score = 204 bits (499), Expect = 3e-51
Identities = 138/450 (30%), Positives = 217/450 (48%), Gaps = 21/450 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DLVVIG G GG +A +AA G KV +E LGGTC+ GC+P K +++ + +
Sbjct: 9 DLVVIGGGSGGVASARRAASYGAKVALIESS-RLGGTCVIRGCVPKKLMMYAAQFGQTLR 67
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
Q G + + F + K + L G A + + + V ++G G I + +V
Sbjct: 68 EGL-QPGWQVTQAEFSMAQWQAAKGKEIDRLEGIYARMLENSGVETIRGHGVIKSTTEVH 126
Query: 153 VHGEKGVETVNTKNILIASGSEV--TPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
V G +NT+ ILIASG+ + FPG+ TS L L ++PK++ VIGAG
Sbjct: 127 V----GERVLNTQRILIASGAAPNRSAFPGLEL----AATSNELLDLSTLPKRVGVIGAG 178
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
I LE + + LG++V+ + + G D + L + QG++ T +
Sbjct: 179 YIALEFACILRGLGSEVSVF-YRGDLPLRGFDEGIRNRLVTAMQLQGIQLFPDTDFKSLS 237
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
++G+T + AA D VL + GR P T+GLGL+ +G+ G I VN
Sbjct: 238 QQGATFDLQTAAANHA------FDFVLNATGRSPNTQGLGLENIGLRTGPAGEIEVNKYS 291
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEG-IKGMPVHFNYDAIPSVIYTSPEVGWV 389
T + G+YA+GDV + L A EG E G + ++ ++P+ +TSP +G V
Sbjct: 292 HTGIKGVYAVGDVTNRVNLTPVAIAEGRALAENEFNGKDLTVDHTSVPTATFTSPPIGSV 351
Query: 390 GKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGE 449
G TEE K +V + F + GE + ++K+L D +D ++G H++G E
Sbjct: 352 GLTEEQAAKRAPT-RVYETEFTPMKTKFSGGEQKTYMKLLVDDASDRVVGIHMLGEDSPE 410
Query: 450 LINEAVLAQEYGAAAEDVARVCHAHPTCAE 479
+I + GA+ D R HP+ AE
Sbjct: 411 MIQLLGVLYTMGASKADFDRTIAVHPSSAE 440
>UniRef50_A2VRE9 Cluster: Dihydrolipoamide dehydrogenase; n=2;
Burkholderia cenocepacia PC184|Rep: Dihydrolipoamide
dehydrogenase - Burkholderia cenocepacia PC184
Length = 389
Score = 204 bits (498), Expect = 4e-51
Identities = 121/326 (37%), Positives = 185/326 (56%), Gaps = 9/326 (2%)
Query: 164 TKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVIGLELGSVYQRL 223
T A+G++ P + F +++ST ALS ++PK+++V+GAG IGLELG VY++L
Sbjct: 65 TTTSCFATGTQAVELPSMPFGG-HVVSSTDALSPATLPKRLVVVGAGYIGLELGIVYRKL 123
Query: 224 GADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKEGSTIKVDVEAA 283
G DV+ +E + D E+ + + L++ G++ LG VLG+ + G+ V V AA
Sbjct: 124 GVDVSVVEAAERVLPA-YDAELVRPVADSLARLGVRLWLGHTVLGLDEHGA---VRVRAA 179
Query: 284 KGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGR-IPVNNKFQTTVPGIYAIGD 342
G ++ L D VL+++GRRP G GL+ + LD GR + +++ +T++ ++AIGD
Sbjct: 180 DGA-EQTLPADRVLVAVGRRPRVDGFGLET--LMLDRNGRALRIDDACRTSMRNVWAIGD 236
Query: 343 VIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGKTEEDLKKEGRA 402
V PMLAH+A +G + E I G F +IP+V +T PE+ G + +D G
Sbjct: 237 VAGEPMLAHRAMAQGEMVAELIAGRRRQFTPASIPAVCFTDPEIVTAGWSPDDAHAAGVD 296
Query: 403 YKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGA 462
FPF AN RA T T+GFV+V++ + +I+G +G G EL + E GA
Sbjct: 297 CLSASFPFAANGRAMTLQATDGFVRVVARRDNHLIVGWQAVGRGVSELAAAFSQSLEMGA 356
Query: 463 AAEDVARVCHAHPTCAEALREANLAA 488
ED+ HAHPT EAL+EA L A
Sbjct: 357 RLEDIGGTIHAHPTLGEALQEAALRA 382
>UniRef50_Q2SKE2 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide dehydrogenase (E3) component,
and related enzyme; n=2; Gammaproteobacteria|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dihydrolipoamide dehydrogenase (E3) component, and
related enzyme - Hahella chejuensis (strain KCTC 2396)
Length = 466
Score = 204 bits (497), Expect = 6e-51
Identities = 143/458 (31%), Positives = 223/458 (48%), Gaps = 7/458 (1%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
D D+VVIGSGP G AA++AA+ G +V +E+D LGG C++ G IPSK L N+ +
Sbjct: 3 DFDIVVIGSGPAGQKAAVQAAKAGKQVALIERDALLGGACVHRGTIPSKTLRENALRVNN 62
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
+ + + E + +++ + +K + +N + + G ++PN+
Sbjct: 63 MRKNATLFQFKLSE-DLEMATLIDRLDDVMKSHDEYMRRQIDRNAIKRIHGRARFLSPNE 121
Query: 151 VEVHGEKGVETV-NTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
VEV +G + V NT ++IA+GS V D + I S LS+ +PK + V+G
Sbjct: 122 VEVTSVRGKKQVLNTDYVVIATGSFPRKPEQVPIDHENIFDSDSVLSMLYLPKSLAVLGG 181
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
GVI E S++Q LG V I+ G +D ++ G + +G V V
Sbjct: 182 GVIASEYASIFQALGVRVIMIDRYPRPLGF-LDKDLTDNFVNAFQDMGGVW-MGNSV--V 237
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
KK DV + ++ +L + GR K L +D G+ALD+RG IPV+ +
Sbjct: 238 KKVCFDGVNDVITELEDGRTIIT-QKLLCAAGREANVKDLDIDNAGLALDERGVIPVDGQ 296
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWV 389
+T VP I+A GDVI P LA + ++G + G+ V + IP IY PE+ V
Sbjct: 297 LRTRVPNIFAAGDVIGPPSLASASMEQGRRAACNVIGLEVGSMPEMIPVGIYGVPELSSV 356
Query: 390 GKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGE 449
G TE++ +K VG+ PF +R +G +G +K++ D +LG I+G E
Sbjct: 357 GMTEQEARKAHGQIIVGRAPFSEIARGHISGNQDGMLKLVCDAEGRRLLGVQIVGEEATE 416
Query: 450 LINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 487
LI+ +A + + PT AEA R A LA
Sbjct: 417 LIHIGQMALLSKSDVDIFVESIFNFPTLAEAYRVAALA 454
>UniRef50_Q8DD46 Cluster: Soluble pyridine nucleotide
transhydrogenase (EC 1.6.1.1) (STH) (NAD(P)(+)
transhydrogenase [B-specific]); n=43; Bacteria|Rep:
Soluble pyridine nucleotide transhydrogenase (EC
1.6.1.1) (STH) (NAD(P)(+) transhydrogenase [B-specific])
- Vibrio vulnificus
Length = 466
Score = 204 bits (497), Expect = 6e-51
Identities = 150/460 (32%), Positives = 227/460 (49%), Gaps = 14/460 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHN-SHLYHMA 91
D++VIGSGPGG AA+ + G+KV VEK+ ++GG C + G IPSKAL H S +
Sbjct: 8 DVIVIGSGPGGEGAAMGLTKAGLKVAVVEKESSVGGGCTHWGTIPSKALRHAVSRIIEFN 67
Query: 92 KHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
+ + + TF ++ + + + T + +N+ L+ G + +
Sbjct: 68 SNPLFCKNNSSLHATFS--TILGHAKSVIDKQTRLRQGFYDRNQCQLIFGTARFTDAHTI 125
Query: 152 EVHGEKGVETVNTKN-ILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
V G E V T + +IA+GS V F+ ++I S LSL+ P+ +++ GAG
Sbjct: 126 SVTQNDGTEEVYTADKFVIATGSRPYQPADVDFNHERIYDSDSILSLKHDPRHIIIYGAG 185
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
VIG E S+++ LG I + +D EV+ L G+ + +
Sbjct: 186 VIGCEYASIFRGLGVKTDLINTRDRLLAF-LDNEVSDALSYHFWNSGVVIRNDETYERI- 243
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
EG+ V V + G K DC +L + GR T L L VG+ D RG++ V+ +
Sbjct: 244 -EGTEDGVIVHL-QSGKKMKADC--LLYANGRTGNTDKLNLPAVGLQGDSRGQLKVDGNY 299
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPEVGWV 389
QT V +YA+GDVI P LA A D+G + I KG + D IP+ IYT PE+ V
Sbjct: 300 QTEVEHVYAVGDVIGYPSLASAAYDQGRFVAQAITKGKADGYLIDDIPTGIYTIPEISSV 359
Query: 390 GKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGE 449
GKTE++L Y+VG+ F +RA+ G+ G +K+L + T ILG H G E
Sbjct: 360 GKTEQELTAAKVPYEVGRSSFKHLARAQIAGKDIGSLKILFHRETKEILGIHCFGERAAE 419
Query: 450 LIN--EAVLAQEYGA-AAEDVARVCHAHPTCAEALREANL 486
+I+ +A++ Q+ A E +PT AEA R A L
Sbjct: 420 IIHIGQAIMEQKGEANTIEYFVNTTFNYPTMAEAYRVAAL 459
>UniRef50_Q0W7Q8 Cluster: Dihydrolipoamide dehydrogenase; n=2;
Euryarchaeota|Rep: Dihydrolipoamide dehydrogenase -
Uncultured methanogenic archaeon RC-I
Length = 456
Score = 203 bits (495), Expect = 1e-50
Identities = 135/433 (31%), Positives = 213/433 (49%), Gaps = 16/433 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL+VIGSG G + + + G KV ++ PT GGTCLN GCIPSK L++ + + A+
Sbjct: 5 DLIVIGSGAGDQIVSYALSD-GSKVALADRGPT-GGTCLNTGCIPSKMLIYPADVIRAAQ 62
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNK-VNLVKGVGTIVAPNKV 151
+ G+ T + DF ++ME N V G G+ +K K + +GV P+ +
Sbjct: 63 -EASAIGVAT-TIKPDFGQIMERMRNFVDGERQGMEEGLRKAKNLAFYQGVAEFTGPHTL 120
Query: 152 EVHGEKGVETVNTKNILIASGSEVT--PFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
+V G + I+IA+G+ V P PG+ E + + L L +PK +++IG
Sbjct: 121 KV----GSHEITAPKIVIATGARVAIPPIPGLK--ETGYLDNVSLLQLREMPKSLIIIGG 174
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
G IG E + +GADVT + + D EV+ T+ K++S+ + + G + V
Sbjct: 175 GYIGCEYAHFFSAMGADVTIVSRPPVLLN-DEDPEVSDTVTKVMSRY-VHVQTGFEADKV 232
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
+EG V ++ K G + D +L+++GRR L +K G+ D +G I VN
Sbjct: 233 GREGDRKVVYAKSKKDGTTASFEADEILVALGRRSNADLLKPEKAGVETDAKGWIKVNKY 292
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEG-IVCVEGIKGMPVHFNYDAIPSVIYTSPEVGW 388
+T+VPGI+AIGD I M H A +V + + A+P ++T P+VG
Sbjct: 293 LETSVPGIWAIGDAIGRYMFRHTANYHAEVVYTNMFSEHKMEVDEHAVPHAVFTHPQVGH 352
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VG TE D K G VG+ ++ ++ +GFVKV+ ILG ++GP
Sbjct: 353 VGMTEADAKAAGIKVLVGRAKYIQTAKGIAMHNHDGFVKVVVTADNKKILGCSVVGPDAA 412
Query: 449 ELINEAVLAQEYG 461
L+ + G
Sbjct: 413 VLVQQVAYMMNCG 425
>UniRef50_Q16881 Cluster: Thioredoxin reductase 1, cytoplasmic
precursor; n=91; Eumetazoa|Rep: Thioredoxin reductase 1,
cytoplasmic precursor - Homo sapiens (Human)
Length = 499
Score = 203 bits (495), Expect = 1e-50
Identities = 145/488 (29%), Positives = 250/488 (51%), Gaps = 27/488 (5%)
Query: 29 THDADLVVIGSGPGGYVAAIKAAQLGMKVVSVE-KDPT-------LGGTCLNVGCIPSKA 80
++D DL++IG G GG AA +AAQ G KV+ ++ PT LGGTC+NVGCIP K
Sbjct: 10 SYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKK- 68
Query: 81 LLHNSHLYHMAKHDFKQRGIETGE-VTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLV 139
L+H + L A D + G + E V D+ +M+E N + L G + ++ KV
Sbjct: 69 LMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYE 128
Query: 140 KGVGTIVAPNKVEVHGEKGVETV-NTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLE 198
G + P++++ KG E + + + LIA+G E + G+ D++ I+S SL
Sbjct: 129 NAYGQFIGPHRIKATNNKGKEKIYSAERFLIATG-ERPRYLGIPGDKEYCISSDDLFSLP 187
Query: 199 SVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGM 258
P K LV+GA + LE +G DVT + + SI G D ++A + + + + G+
Sbjct: 188 YCPGKTLVVGASYVALECAGFLAGIGLDVTVM--VRSILLRGFDQDMANKIGEHMEEHGI 245
Query: 259 KFKLGTKVLGVK--KEGSTIKVDVEAAKGGNKEVL--DCDVVLISIGRRPYTKGLGLDKV 314
KF + V+ + G+ ++ V A ++E++ + + V+++IGR T+ +GL+ V
Sbjct: 246 KFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETV 305
Query: 315 GIALDDR-GRIPVNNKFQTTVPGIYAIGDVIHGPM-LAHKAEDEGIVCVEGI-KGMPVHF 371
G+ ++++ G+IPV ++ QT VP IYAIGD++ + L A G + + + G V
Sbjct: 306 GVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKC 365
Query: 372 NYDAIPSVIYTSPEVGWVGKTEED-LKKEG----RAYKVGKFPFLANSRAKTNGETEGFV 426
+Y+ +P+ ++T E G G +EE ++K G Y +P ++ N + +
Sbjct: 366 DYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI 425
Query: 427 KVLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANL 486
+ + K + ++G H++GP GE+ A + G + + HP CAE ++
Sbjct: 426 -ICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSV 484
Query: 487 AAYSGKPI 494
SG I
Sbjct: 485 TKRSGASI 492
>UniRef50_UPI000038D9FE Cluster: COG1249: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide dehydrogenase
(E3) component, and related enzymes; n=1; Nostoc
punctiforme PCC 73102|Rep: COG1249:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dihydrolipoamide dehydrogenase (E3) component, and
related enzymes - Nostoc punctiforme PCC 73102
Length = 472
Score = 202 bits (494), Expect = 1e-50
Identities = 135/465 (29%), Positives = 233/465 (50%), Gaps = 16/465 (3%)
Query: 29 THDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTL-GGTCLNVGCIPSKALLHNSHL 87
T D ++IG G G A G K VE+ + GG C+N+ CIP+K ++ ++++
Sbjct: 5 TQHYDDIIIGGGKAGKTLAPALVADGRKTALVERSLNMIGGGCINIACIPTKTMVASANV 64
Query: 88 YHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTG-GIAMLFQKNKVNLVKGVGTIV 146
+ ++ G++ D ++++ K V+ + L NL+ G V
Sbjct: 65 ANTVRNSAAY-GVKANTPIVDLAEVIQRKRAVVQSAREMNLHNLETALDKNLIIGEARFV 123
Query: 147 APNKVEVHGEKGVETVNT-KNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKK 203
AP +EV +G + T + + I +G+ + PG+T E + +TS + LE +P+
Sbjct: 124 APKTIEVTTTEGKNRLLTAERLFINTGTRPLIPSIPGLT--EVEFLTSESIMELEYLPEH 181
Query: 204 MLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLG 263
++V+G+G IGLE +++R G VT I I D ++A +Q +L + G++F L
Sbjct: 182 LIVLGSGYIGLEFAQMFRRFGCGVTVIGQSEQILSQQ-DPDIAIAVQTLLERNGIEFLLK 240
Query: 264 TKVLGVKKEGSTIK-----VDVEAAKGGNKEV-LDCDVVLISIGRRPYTKGLGLDKVGIA 317
KVL V ++ S ++ + + G++E+ L +L+++GR P T L L G+A
Sbjct: 241 AKVLRVVRKASPLENRTGNETILQIQVGDREITLQGSHLLVAVGRAPNTDSLNLAAAGVA 300
Query: 318 LDDRGRIPVNNKFQTTVPGIYAIGDVIHGPMLAH-KAEDEGIVCVEGIKGMPVHFNYDAI 376
D RG I VN++ +T +PGI+A+GD+ GP H +D I+ I G +
Sbjct: 301 TDTRGFIQVNDRLETNIPGIWALGDINGGPQYTHISLDDYRIIKANLIDGGDRSTGDRLV 360
Query: 377 PSVIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDV 436
PS ++ +PE+ VG TE + +++G A +V K A RA+T G+T+G +K + D T
Sbjct: 361 PSCLFIAPELAHVGLTETEAQQQGYAIRVAKIDASAVPRARTLGQTDGLLKAIMDTETGR 420
Query: 437 ILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
ILG ++ GE+I+ + + + HPT E L
Sbjct: 421 ILGCSLLCHEAGEVISTVQMVMQAQMPYTILRDGILTHPTMTEGL 465
>UniRef50_Q11PG6 Cluster: Pyridine nucleotide-disulphide-related
oxidoreductase; n=1; Cytophaga hutchinsonii ATCC
33406|Rep: Pyridine nucleotide-disulphide-related
oxidoreductase - Cytophaga hutchinsonii (strain ATCC
33406 / NCIMB 9469)
Length = 496
Score = 202 bits (494), Expect = 1e-50
Identities = 138/459 (30%), Positives = 225/459 (49%), Gaps = 12/459 (2%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+ +IG+GP GY AA++A L V+ +EKD +GG L G I SK + A+
Sbjct: 4 DVCIIGAGPAGYAAAMRALDLNKSVILIEKDK-IGGAGLYNGAISSKTFWELAKDIQTAR 62
Query: 93 HDFKQRGIETG-EVTFD--FKKMMEYKANAVKGLTGGIAMLF--QKNKVNLVKGVGTIVA 147
Q + VT+ +++ E AN L G I L Q ++ +KG +V+
Sbjct: 63 KRLAQYSPDQHFSVTYQQVLRQVREGIANRRFHLEGQIESLAKQQTSRFRYIKGSAKLVS 122
Query: 148 PNKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVI 207
N VEV E + +N++IA+GS+ P + DEK I+TS G + E+ PK ++++
Sbjct: 123 HNTVEVSTGTEEEIIEAENVVIATGSKPRKLPNIPIDEKIIVTSDGVENFENFPKSLVIL 182
Query: 208 GAGVIGLELGSVYQRLG-ADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
GAGVIG E +++ G V I+ I D +V ++ + KQG+ + +
Sbjct: 183 GAGVIGCEWATIFSNFGYTSVNIIDKAERILPFE-DDDVTDVVEANMKKQGITVHKKSNL 241
Query: 267 LGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPV 326
L ++ ++ +E G KE+ + VL+S+GR P T+ LGL++VG+ + G+I
Sbjct: 242 LSMRIVDGEVEYILEYT-DGRKEMHRVEKVLVSVGRIPNTQNLGLERVGVNILANGQIE- 299
Query: 327 NNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH-FNYDAIPSVIYTSPE 385
N QT +P IY GD+ L + AE EG +E + G+ Y+ + ++++ PE
Sbjct: 300 NTDGQTNIPNIYVAGDISSDVALVNVAELEGRHVIEKMFGLSDSVITYNNVSTIMFVQPE 359
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDV-ILGTHIIG 444
V VG E+ + +YKV K + RA +GF K+L D+ I+G +G
Sbjct: 360 VAGVGMNEKKALQNKMSYKVVKIRYDMIPRAIAMRNNDGFFKILVTNDADMKIIGMRAVG 419
Query: 445 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
I L E++A + H HP+ E ++E
Sbjct: 420 VHASSAIQAVALLISMDKGVEELADMIHPHPSIIEGIQE 458
>UniRef50_Q1GQ53 Cluster: Mercuric reductase MerA; n=91;
Bacteria|Rep: Mercuric reductase MerA - Sphingopyxis
alaskensis (Sphingomonas alaskensis)
Length = 479
Score = 202 bits (492), Expect = 2e-50
Identities = 139/458 (30%), Positives = 225/458 (49%), Gaps = 17/458 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHN-SHLYHMA 91
DL+V+G G G+ AAI AA+ G +V + T+GGTC+NVGC+PSKAL+ ++H
Sbjct: 17 DLIVVGGGSAGFSAAITAAEQGAQVAVIGAG-TIGGTCVNVGCVPSKALIRAVESIHHAN 75
Query: 92 KHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGG--IAMLFQKNKVNLVKGVGTIVAPN 149
+ G+E G D+ K++ K + V GL +L N + +G +V N
Sbjct: 76 AAPMRFNGVEAGARMADWGKVIAEKDSLVSGLRQAKYADLLPLYNNIAYHEGTARLVE-N 134
Query: 150 KVEVHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVI 207
VE G + I+IA+G+ V PG+ + + ST AL L +PK M+V+
Sbjct: 135 GVEAGGRR----FTADRIVIATGTRPAVPAIPGLP--DVDALDSTTALDLTELPKSMIVL 188
Query: 208 GAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVL 267
G G IG+EL ++ R G DVT + F + + ++ E+ L LS +G+ LG
Sbjct: 189 GGGYIGVELAQMFSRAGVDVTLV-FRSRLLP-DMEPEIGAALTDYLSSEGITV-LGDLAY 245
Query: 268 GVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVN 327
+ + + + G E + + +L++ GR P + LGL + G+ G I V+
Sbjct: 246 QSAHKTAEGGTALTVLRNGVAETIVAERLLVATGRAPNVEDLGLIEAGVKQTLSGAIIVD 305
Query: 328 NKFQTTVPGIYAIGDVIHGPMLAHKAE-DEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEV 386
+ +T+V G+YA GDV + A I + G + ++ A+P+V+++ P+V
Sbjct: 306 DHMRTSVRGVYAAGDVTGRDQFVYMAAYGAKIAAKNALNGDSLRYDNSAMPAVVFSDPQV 365
Query: 387 GWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPG 446
VG TE G A + P RA +T G +K+++D T +LG HI+ P
Sbjct: 366 ASVGFTEAQAIAAGYATRTSTLPLENVPRALAARDTRGLIKLVADGRTRKLLGAHILAPE 425
Query: 447 GGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
G + I A +A G +D+A + + T E L+ A
Sbjct: 426 GADSIQTAAMAIRCGLTIDDLAEMIFPYLTTVEGLKLA 463
>UniRef50_UPI00006A2AB5 Cluster: UPI00006A2AB5 related cluster; n=2;
Xenopus tropicalis|Rep: UPI00006A2AB5 UniRef100 entry -
Xenopus tropicalis
Length = 597
Score = 201 bits (490), Expect = 4e-50
Identities = 110/341 (32%), Positives = 186/341 (54%), Gaps = 4/341 (1%)
Query: 143 GTIVAPNKVEVHGEKG-VETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVP 201
G ++ P V GE+G + + +I++A+G+ P P + + + + + AL+ ++P
Sbjct: 259 GGLITPIVAVVTGERGSTQELRAAHIVLATGARARPLPQLPVNGQSVWSYREALTPPALP 318
Query: 202 KKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFK 261
+++L+IGAG IG+E S Y+ +G++V +E + D +++ + L K G++
Sbjct: 319 QRLLIIGAGAIGIEFASFYRAVGSEVAVVEMAPRVLPQE-DEDISAQVAASLQKDGIQVH 377
Query: 262 LGTKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDR 321
V ++ T ++ + + + L DVVL++ G + LGL+K + +++
Sbjct: 378 TQVVVEQAQRAHDTWQITLRQSGADSTWQLQADVVLVAAGIVGNVEDLGLEKTRVQVEN- 436
Query: 322 GRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH-FNYDAIPSVI 380
I + +T PG+YA+GDV P LAHKA EG++CVE I G+P H + +
Sbjct: 437 SHIVTDALCRTAEPGVYAVGDVAGPPWLAHKASHEGVLCVEHIAGLPTHALEPHRVSACT 496
Query: 381 YTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGT 440
Y+ P+V VG TE K GRA KVGKFPF AN +A GET+GFVKV+ D T+ +LG
Sbjct: 497 YSHPQVASVGWTEAQAKAAGRAVKVGKFPFAANGKAIAMGETQGFVKVVFDATSGELLGA 556
Query: 441 HIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
H++G E+I +AQ + ++ HPT +E++
Sbjct: 557 HMVGEEVTEMIQGFAIAQRLESTEAELMNTILPHPTLSESM 597
>UniRef50_Q1AV54 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
- Rubrobacter xylanophilus (strain DSM 9941 / NBRC
16129)
Length = 448
Score = 200 bits (489), Expect = 5e-50
Identities = 140/451 (31%), Positives = 222/451 (49%), Gaps = 21/451 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D VV+G GPGG VAA + G +V VEK+ +GG C CIPSK LL + A+
Sbjct: 6 DAVVLGMGPGGEVAASRLISGGKRVAVVEKE-LIGGECAYWACIPSKTLLRPPEVRGEAR 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAML-FQKNKVNLVKGVGTIVAPNKV 151
R TG + + + +Y+ ++ L + +++ +VKG G IV P KV
Sbjct: 65 -----RAFGTGVPELEMEAIFDYRDYMIRNLDDAAQVEGYERQGATVVKGAGKIVGPGKV 119
Query: 152 EVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGV 211
E GE T+ +I++A+GS P DE + T+ + VP++ L++G G
Sbjct: 120 EADGE----TIEAGHIVVATGSAPNVPPVEGLDEITVWTNREVTTSREVPRRALIVGGGP 175
Query: 212 IGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKK 271
G+E R G++VT ++ + D V + ++ L +G++ G K ++
Sbjct: 176 NGIEAAQWLSRFGSEVTIVQSADRLIDRE-DPRVGELIRGALEGEGIRVLTGRKAARARR 234
Query: 272 EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQ 331
+G V+++ EV DVV+I+ GRRP T+GLGL+ VGI D G IPV+++ +
Sbjct: 235 DGEGAVVELD----DGAEV-GTDVVVIAAGRRPRTEGLGLETVGIE-PDGGAIPVDDRCR 288
Query: 332 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGK 391
G++AIGD + H A+ +G V + I G +Y IP V+++ PE+ G
Sbjct: 289 AA-EGVWAIGDATGVALFTHVAKYQGRVAADNILGRERRADYRGIPRVVFSDPEIAACGL 347
Query: 392 TEEDLKKEGRAYKVGKFPF-LANSRAKTNGE-TEGFVKVLSDKTTDVILGTHIIGPGGGE 449
TEE ++EG A A +R T E G + +++D+ V++G + P GE
Sbjct: 348 TEEQARREGMATATATLDLSRAIARPYTYEEDPRGTLSLVADRKRGVLVGAWAVAPLAGE 407
Query: 450 LINEAVLAQEYGAAAEDVARVCHAHPTCAEA 480
I+EA LA E + PT +EA
Sbjct: 408 WIHEAALAIRAEVPIEKLLDSVAQFPTYSEA 438
>UniRef50_Q9HLL9 Cluster: Dihydrolipoamide dehydrogenase component
(E3) related protein; n=2; cellular organisms|Rep:
Dihydrolipoamide dehydrogenase component (E3) related
protein - Thermoplasma acidophilum
Length = 451
Score = 200 bits (488), Expect = 7e-50
Identities = 136/463 (29%), Positives = 222/463 (47%), Gaps = 22/463 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D++ IG+G Y AA + + G V+ ++K + G CL GC+PSKA++ H +
Sbjct: 5 DVITIGAGGAAYPAAFRLKRSGFSVLMIDKKGVMSGNCLAEGCVPSKAVIETVHNLAKMR 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
H G+ + D+ K++++K + ++ + ++KG I+ N VE
Sbjct: 65 H--------FGDYSIDYSKIVDHKDSVQNIRYEQHDQELKEAGLKIIKGTARIIDDNTVE 116
Query: 153 VHGEKGVETVNTKN-ILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
V + G + + I+IASGSE V PG + ++ +PK + +IG
Sbjct: 117 VSSDTGTSRYRSSSAIIIASGSETFVPKIPGAELAWTSADLYSLKPKVKKLPKSIAIIGG 176
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
G IG+E S LG VT IE L + +D + L +L K M + + V +
Sbjct: 177 GYIGMETASFMSILGVKVTVIEMLDRVMST-MDEAMVDKLLPLLPK--MDIRTASPVQSI 233
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
++ GS V+ K G KE ++ + VL+++GR P G+D +GI D G I VN
Sbjct: 234 ERNGSMYHVNF--GKEGEKESIEVEAVLMAVGRVPVFPE-GIDDLGIEHDRHG-IKVNMA 289
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI--KGMPV-HFNYDAIPSVIYTSPEV 386
QT + IYA GDV L H A+ + +V I +P+ +F+ ++P +YT P++
Sbjct: 290 MQTNIKNIYATGDVNGITPLFHAAKRQSLVAANNIMANNVPIDYFDPLSVPFTVYTIPQM 349
Query: 387 GWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPG 446
+VG +K G Y + ++ A+ N E G +++ +DK VI G ++IG
Sbjct: 350 AYVGILPSQARKMGIEYLETDYQIEKDALAQINNEMFGEIRIFTDKRMKVI-GGYVIGND 408
Query: 447 GGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAY 489
G +INE LA G + D+A + H HP E + A Y
Sbjct: 409 AGNVINEIALAVSKGLSLRDLAEMAHQHPMTFEGIDSAARKLY 451
>UniRef50_Q8E285 Cluster: Pyridine nucleotide-disulphide
oxidoreductase family protein; n=17; Streptococcus|Rep:
Pyridine nucleotide-disulphide oxidoreductase family
protein - Streptococcus agalactiae serotype V
Length = 439
Score = 200 bits (487), Expect = 9e-50
Identities = 137/452 (30%), Positives = 216/452 (47%), Gaps = 30/452 (6%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTL-GGTCLNVGCIPSKALLHNSHLYHMA 91
D++V+G G G A K A G V VE+D + GGTC+N+GCIP+K LL ++
Sbjct: 5 DVIVLGFGKAGKTLAAKLATQGKSVAMVEEDDKMYGGTCINIGCIPTKTLLVSAS----K 60
Query: 92 KHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
HDF++ EVT + AML K+ V++ ++ V
Sbjct: 61 NHDFQEAMTTRNEVTSRLRAK-------------NFAMLDNKDTVDVYNAKARFISNKVV 107
Query: 152 EVHGEKGVETVNTKNILIASGSEVT--PFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
E+ G + + I+I +G++ P PG+ D + + ST L +PK++ +IG
Sbjct: 108 ELTGGADKQELTADVIIINTGAKSVQLPIPGLA-DSQHVYDSTAIQELAHLPKRLGIIGG 166
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
G IGLE ++Y LG+ VT I+ + I + E+++ Q L + G+ FKL + V
Sbjct: 167 GNIGLEFATLYSELGSKVTVIDSQSRIFARE-EEELSEMAQDYLEEMGISFKLSADIKSV 225
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
+ E + + E K L D VL + GR+P T+GL L+ I L +RG I V+
Sbjct: 226 QNEDEDVVISFEDEK------LSFDAVLYATGRKPNTEGLALENTDIKLTERGAIAVDEY 279
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHF--NYDAIPSVIYTSPEVG 387
QT+V I+A+GDV GP + + D+ + + + + N A+P+ +T+P +
Sbjct: 280 CQTSVENIFAVGDVNGGPQFTYISLDDSRIVLNYLNCDKDYSLKNRGAVPTSTFTNPPLA 339
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG E+ K++G K A RA N + G KV+ D T++ILG + G
Sbjct: 340 TVGLDEKTAKEKGYQVKSNSLLVSAMPRAHVNNDLRGIFKVVVDTETNLILGARLFGAES 399
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAE 479
ELIN +A + + HPT E
Sbjct: 400 HELINIITMAMDNKIPYTYFQKQIFTHPTMVE 431
>UniRef50_A7I8G1 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=1; Candidatus
Methanoregula boonei 6A8|Rep: Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
- Methanoregula boonei (strain 6A8)
Length = 462
Score = 200 bits (487), Expect = 9e-50
Identities = 140/454 (30%), Positives = 221/454 (48%), Gaps = 18/454 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DLV+IG+G G AA A LG V+V + L GTC+N GCIPSK LL + +
Sbjct: 6 DLVIIGTGAAGVAAATAAVHLGASRVAVVERGPLWGTCVNTGCIPSKFLLTLAGYTYYRG 65
Query: 93 HDF---KQRG-IETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAP 148
H + G ++ GEV + K ++ + K T LF + V L++G T + P
Sbjct: 66 HSHPGVRMEGRLDLGEVLAE-KNTLQERLREKKRDT-----LFSRLGVELIEGEATFLNP 119
Query: 149 NKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
+ ++ K + +K +IA+GS P +TS ALS E +P ++VIG
Sbjct: 120 HTLQAGDRK----LASKRFIIATGSSPAIPPVEGIGSVPFMTSADALSPERIPATLIVIG 175
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
+GLE +Y LG VT ++ I + E+A + L+ +G+ G +
Sbjct: 176 GRALGLEFAQLYSHLGTRVTLLQRSPRILPEE-EPEIADLMAGYLAGEGIGILTGVDIKR 234
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
V++ G ++ V A G + V+ D +L++ GR P ++ L G+ G + V+
Sbjct: 235 VERTGDSVAVI--AGTRGEQRVISADRLLLATGRTPNSRELNCGAAGVDTRPDGAVVVDT 292
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEG-IVCVEGIKGMPVHFNYDAIPSVIYTSPEVG 387
QT+ P I+A GDV PML A G I ++ + +N +P I+T+P+V
Sbjct: 293 MLQTSAPHIWAAGDVTGEPMLETAARYGGEIAASNALRELKRSYNSALLPHGIFTTPQVA 352
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG TE+ +K G + ++ +G+T G VK+++DK + ILG H+ P
Sbjct: 353 GVGMTEDRAQKAGLNPVSHSIRTDSMAKFSIDGDTRGMVKIVADKRSRRILGVHLCAPLA 412
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
E+I E V+A A+D+A + H PT EAL
Sbjct: 413 TEMIQEGVIAVTRYLTADDLAELPHVFPTATEAL 446
>UniRef50_Q98C99 Cluster: Mercuric reductase; n=4;
Proteobacteria|Rep: Mercuric reductase - Rhizobium loti
(Mesorhizobium loti)
Length = 509
Score = 199 bits (486), Expect = 1e-49
Identities = 140/457 (30%), Positives = 224/457 (49%), Gaps = 17/457 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
+LVVIG+GP G AA AA LG KV +E+ +GG C+NVG +PSK+++ + LY +
Sbjct: 39 NLVVIGAGPAGLTAARDAASLGAKVALIERG-LIGGACVNVGGVPSKSIIRTARLYADMR 97
Query: 93 HDFKQRGIETGEVTFDFKK-MMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
G + DF++ MM + + A ++L G P+ V
Sbjct: 98 DAENFGGDTPARLPVDFERAMMRMRQIRQRLSRADSAAAITAEGIDLYFGEARFGGPDTV 157
Query: 152 EVHGEKGVETVNTKNILIASGSEVT--PFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
EV G+ T++ K L+A+G+ + PG+ E + + +L P+++LVIG
Sbjct: 158 EVAGK----TLHFKKALVATGAHPSGPAIPGLA--EAGYLDNESMFNLTRRPERLLVIGG 211
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
G +G E + LGA V + + G + + A+ L L+++G++ +L T+V+ V
Sbjct: 212 GPLGCETAQAFCLLGAKVILAQS-DPMFLPGEERDAAQILSDTLAREGVEVRLNTEVVAV 270
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
+KEG D+ + G+ + D ++ +GR P +GLGL++ G+ D G I V++
Sbjct: 271 RKEGGRKLADL--LRDGDTTTISVDEIITGVGRSPNVRGLGLEEAGVVYDANG-IKVDDH 327
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEG--IKGMPVHFNYDAIPSVIYTSPEVG 387
+TT P IYA GDV H AE + V +G + +P YT PE+
Sbjct: 328 LRTTNPHIYAAGDVCLEYKFTHTAEAAARIVVRNALFRGRE-RLSDLVVPWCTYTDPEIA 386
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG + ++ G K +RA +GE EGFVK+ + +D ILG ++
Sbjct: 387 HVGLYPIEARQNGIPVKTYTVLMHDVARAVMDGEEEGFVKIHVREGSDRILGATVVASHA 446
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
GE+IN LA G +A V HA PT A+ ++ A
Sbjct: 447 GEMINAVTLAIRSGMGLHALADVIHAFPTQAQGIKMA 483
>UniRef50_A3ZMG9 Cluster: Mercuric reductase; n=1; Blastopirellula
marina DSM 3645|Rep: Mercuric reductase -
Blastopirellula marina DSM 3645
Length = 505
Score = 199 bits (486), Expect = 1e-49
Identities = 133/455 (29%), Positives = 225/455 (49%), Gaps = 17/455 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
+L+ IG G G ++A+ A LG +E+ LGG CLN GC+PSK+L+ ++ H A
Sbjct: 35 NLIAIGGGSAGIISALGATGLGGTSALIERK-LLGGDCLNYGCVPSKSLIRSARAAH-AF 92
Query: 93 HDFKQRGIE-TGEVTFDFKKMMEYKANAVKGLTGGIAML-FQKNKVNLVKGVGTIVAPNK 150
G+ + +F ++ME ++ A L F V++ G VAP+
Sbjct: 93 ATAPSYGVNPVCDPRVEFAQVMERMRRVRADISRHDAALRFAGMGVDVYLGGAKFVAPDA 152
Query: 151 VEVHGEKGVETVNTKNILIASGS--EVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
V V G+ T+ +IA+G ++ P PG+ +E +T+ SL +P ++ V+G
Sbjct: 153 VTVAGQ----TLKFARCVIATGGRPQIPPIPGL--EESGYLTNETIFSLTKLPARLAVLG 206
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
G IG E+ + R G++V IE + I D ++ +++ L+++G++ L V
Sbjct: 207 MGPIGTEMAQTFGRFGSEVHGIERQSRILSRE-DPSASEVVRQQLAREGVQLHLNHLVTH 265
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
V++ G +V +E G ++L+ D +L+++GRRP +GL LDK G+ + +G I VN+
Sbjct: 266 VERIGDVTRVTIEGE--GESKILEVDAILVALGRRPNVEGLDLDKAGVQFNKKGVI-VND 322
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMP-VHFNYDAIPSVIYTSPEVG 387
+ QTT P I+A GD+ H A+ VC+ + +P Y+ PEV
Sbjct: 323 RLQTTNPRIFAAGDIAGSYQFTHAADAMARVCLRNALFYGNARLSSLIMPRTTYSDPEVA 382
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG T +++G + RA +GET GF + + + + ++G I+ P
Sbjct: 383 HVGMTPAQAQEQGLLIDSYREEMKGVDRAAVDGETAGFAVIHTRRGSGKVVGATIVAPHA 442
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALR 482
GE+I E L + +A V H +PT E L+
Sbjct: 443 GEMIGEITLLMSTRRTLDTLADVIHCYPTQVEVLK 477
>UniRef50_A0SNY8 Cluster: Mercuric reductase; n=1; uncultured
euryarchaeote ARMAN-2|Rep: Mercuric reductase -
uncultured euryarchaeote ARMAN-2
Length = 471
Score = 198 bits (484), Expect = 2e-49
Identities = 132/460 (28%), Positives = 226/460 (49%), Gaps = 17/460 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPT----LGGTCLNVGCIPSKALLHNSHLY 88
D V+IG G + AAIKA +LG + + K+ T LGGTC+NVGC+PSK ++ + +
Sbjct: 5 DYVIIGQGSAAFSAAIKANELGKNTLMIGKNATAGAVLGGTCINVGCVPSKRMISVARFF 64
Query: 89 HMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIA--MLFQKNKVNLVKGVGTIV 146
+ GI + ++++++E K +K L ++ V+ + G+
Sbjct: 65 KELSLK-RFGGINYDLGSLEYERVVEEKDELLKTLHKSKYEDVIGSMENVHYLNEFGSFT 123
Query: 147 APNKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEK-QIITSTGALSLESVPKKML 205
+ ++ G+K +E +LIA+G+ P + EK + + AL+L+ +P+ ++
Sbjct: 124 SRTSIKA-GKKEIEA---DRVLIATGARAF-IPKIEGIEKIDYLDNEKALALKGLPRSII 178
Query: 206 VIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTK 265
V+G +GLE ++ G+ VT ++ +I + +AK L+K L + G+
Sbjct: 179 VVGGRAVGLEFAQMFSMFGSKVTVLQRSPTILP-NWEPVIAKRLEKYLIEDGIDVITNAA 237
Query: 266 VLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIP 325
K I VDVE GN + + +L++ GR P T L L+K + G +
Sbjct: 238 PKKFYKSEGKIMVDVEL--DGNVKTFSAEKLLMATGRAPNTDMLDLEKASVETYGNGFVK 295
Query: 326 VNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEG-IKGMPVHFNYDAIPSVIYTSP 384
++N +T GI+A GDV PML A EG + + G + N + +PS ++T P
Sbjct: 296 IDNTMRTGSTGIFAAGDVTGSPMLETLAAKEGNLATQNAFGGGKLKININEVPSAVFTEP 355
Query: 385 EVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 444
E VGKTEE + + + P A ++A +T G +KV+ + T ILG H++
Sbjct: 356 EAAMVGKTEEQVISDLKNCGCNVLPAYAIAKANIISDTRGLIKVVINPKTHEILGVHMLA 415
Query: 445 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
G +LI+E V+A ++ ED+ H PT +E + A
Sbjct: 416 HGAADLIHEGVMAVKFHLKLEDIIDTVHVFPTMSEGFKLA 455
>UniRef50_A2RPR6 Cluster: 2-oxoglutarate dehydrogenase, E3
component, lipoamide dehydrogenase protein; n=1;
Herbaspirillum seropedicae|Rep: 2-oxoglutarate
dehydrogenase, E3 component, lipoamide dehydrogenase
protein - Herbaspirillum seropedicae
Length = 276
Score = 198 bits (483), Expect = 3e-49
Identities = 104/216 (48%), Positives = 140/216 (64%), Gaps = 11/216 (5%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEK------DPTLGGTCLNVGCIPSKALLHNSH 86
D+VVIG GPGGY+AAI+AAQLG +++ P GGTC NVGCIPSKALL +S
Sbjct: 6 DVVVIGGGPGGYIAAIRAAQLGFNTACIDEWKNEKGGPAPGGTCTNVGCIPSKALLQSSE 65
Query: 87 LYHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIV 146
Y A H F + GIE + + +KM+ K VK GI LF+KNKV+ G G+ V
Sbjct: 66 HYEHASHGFAEHGIEVKGLGLNLEKMLGRKNTVVKQNNDGILYLFKKNKVSFFHGRGSFV 125
Query: 147 APN----KVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPK 202
+ +++V G ET+ K++++A+GS PG FDEK I+++TGALS+ VPK
Sbjct: 126 KGDANGYEIKVAGA-AEETITAKHVIVATGSNARALPGAEFDEKLILSNTGALSITEVPK 184
Query: 203 KMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGG 238
K+ VIGAGVIGLE+GSV++RLGA+VT +E L + G
Sbjct: 185 KLGVIGAGVIGLEMGSVWRRLGAEVTVLEALADLPG 220
>UniRef50_Q8KB36 Cluster: Dihydrolipoamide dehydrogenase; n=2;
Chlorobaculum tepidum|Rep: Dihydrolipoamide
dehydrogenase - Chlorobium tepidum
Length = 467
Score = 196 bits (478), Expect = 1e-48
Identities = 141/456 (30%), Positives = 212/456 (46%), Gaps = 14/456 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+++IG GPGG AA++ A G V+ VE+ LGG CL VGCIPSK + H + Y +
Sbjct: 6 DVIIIGGGPGGTPAAMQLASQGKTVLLVEESGKLGGACLFVGCIPSKIIRHWADEYAVKL 65
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNL--VKGVGTIVAPNK 150
Q + + + ++M K + G AM K+ NL V G V+ N+
Sbjct: 66 KYSAQEALSPEDREAAWNEIMR-KMQTILSQRSGAAMQMLKHLSNLRFVAGHAKFVSNNE 124
Query: 151 VEVH----GEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLV 206
+ ++ G K T N I S S + PF G + ++TS S + +P+ +L+
Sbjct: 125 LVINEKDTGRKEKYTFNKAIIATGSHSFIPPFKGNGVQD--VLTSEVLFSQDKLPESLLI 182
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
IG G IG+EL + +LG T IE L SI ++ E + LS G+ ++V
Sbjct: 183 IGGGPIGIELAQMLTKLGTKCTIIELLDSILYGVVETEFVSIISNQLSSLGVNIYTSSQV 242
Query: 267 LGVKKEGSTIKVDVEAAKGG-NKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIP 325
+ K V A G +KE + + VL+ G+ P + L LD I D +G I
Sbjct: 243 QEINKSDGHFDVTFTDANGSEHKE--NFEDVLVVTGKVPNIESLNLDSTDIKYDRKG-II 299
Query: 326 VNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIK-GMPVHFNYDAIPSVIYTSP 384
V+ +T+V GIYA GDV HGP AH A E + I G ++ V+++ P
Sbjct: 300 VDEYLETSVKGIYATGDVTHGPKFAHTATYEAHIASANISAGNNQKVDFSKNTWVLFSEP 359
Query: 385 EVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 444
E+ G TE +EG G + + ++ A+ G++K + +K I+G HI
Sbjct: 360 EIVAAGFTEAQAVQEGYDIITGVYDYKIDAAAQVMNSPFGYLKYVVNKKNSEIIGVHICM 419
Query: 445 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEA 480
L EA L ++VA H HPT EA
Sbjct: 420 NNASSLAGEASLIIANRLILKNVAETIHPHPTLTEA 455
>UniRef50_Q978K3 Cluster: Pyruvate dehydrogenase E3 /
dihydrolipoamide dehydrogenase; n=3;
Thermoplasmatales|Rep: Pyruvate dehydrogenase E3 /
dihydrolipoamide dehydrogenase - Thermoplasma volcanium
Length = 450
Score = 196 bits (478), Expect = 1e-48
Identities = 138/464 (29%), Positives = 223/464 (48%), Gaps = 25/464 (5%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D++ +G+G Y AA + + G V+ ++K + G CL GC+PSKA++ H Y K
Sbjct: 5 DVITLGAGGAAYPAAFRLKKSGYSVLMIDKKGIMSGNCLAEGCVPSKAIIETVHNYSKLK 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ G+ + ++ ++++K + + + ++KG ++ N VE
Sbjct: 65 --------KFGKYSIAYEDIVKHKDDVQNIRYKQHDEELHEAGLKILKGTAKLIDENTVE 116
Query: 153 VHGEKGVETVNTKNILIASGSE--VTPFPG--VTFDEKQIITSTGALSLESVPKKMLVIG 208
V + G E ++I+I +GS+ V PG + + +++ + +PK + +IG
Sbjct: 117 VETDTGKERYRAESIIIGTGSDTYVPKIPGAELAWTSRELYALNP--KVRKLPKSIAIIG 174
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
G IGLE S LG DVT IE L + G V+K L +L K M L + V
Sbjct: 175 GGYIGLETASFMSLLGTDVTVIELLDRVLSTMDSGMVSK-LVPLLPK--MNLILSSPVKE 231
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
+++ G +V + G E + + VL+++GR P GLD +GI D G I VN
Sbjct: 232 IRRGGDMFEVSYD--HEGKTEKIRVEAVLMAVGRMPMFPE-GLDDLGIKYDKHG-IKVNM 287
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKG--MPV-HFNYDAIPSVIYTSPE 385
QT + IYA GDV L H A+ + +V I +PV +F+ ++P +YT P+
Sbjct: 288 AMQTNIKHIYATGDVNGLTPLFHAAKRQSLVAANNIMANHVPVDYFDPLSVPFTVYTVPQ 347
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGP 445
V +VG + KK G +Y + ++ A+ N E EG +++ D +I G ++IG
Sbjct: 348 VAYVGILPDQAKKLGISYIETDYQMEKDAMAQVNSEMEGEIRLFFDSRMKII-GGYVIGN 406
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAY 489
G LINE L G +A D A + H HP E L A Y
Sbjct: 407 DAGNLINEIALGISKGLSARDFAEMAHQHPMSFEGLDSAARKLY 450
>UniRef50_A7BE73 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 465
Score = 196 bits (477), Expect = 1e-48
Identities = 134/461 (29%), Positives = 220/461 (47%), Gaps = 19/461 (4%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
+ DL+V+G G G A++ A+ G KV VE+ +GGTC+NV CIP+K+L++++
Sbjct: 8 NVDLLVVGGGKAGKSLAMERAKAGWKVAMVERQ-FVGGTCINVACIPTKSLVNSARRLSD 66
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
A+ D + T D K+ +K V + G +F ++ ++G
Sbjct: 67 ARSDEAFGVVGTEGARVDLAKLRAHKEGIVGAMVGAHEKMFAAPGLDFIRGEARFTGERT 126
Query: 151 VEVHGEKGVE-TVNTKNILIASGSEVT--PFPGVTFDEKQIITSTGALSLESVPKKMLVI 207
V + E G E T+ + +LI GS PG+ E T+ L LE +P + +I
Sbjct: 127 VTIALEDGGERTIRGERVLINLGSRPARPAIPGLW--ESGAWTNEEILRLEELPSSLAII 184
Query: 208 GAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVL 267
GAG IG+E S+ G DVT I + D + A+ ++ L G++ G +
Sbjct: 185 GAGYIGVEFASMMATFGVDVTLISSGDHVLPRE-DEDAARVVEAGLEAAGVRIVPG-RAE 242
Query: 268 GVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVN 327
+EG+T + + + + + VL+++GR P T G+GLD+ G+ L DRG + V+
Sbjct: 243 SASREGNTTTLTLS-----DGSTVSAEAVLVAVGRVPNTDGIGLDEAGVELTDRGFVAVD 297
Query: 328 NKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH-----FNYDAIPSVIYT 382
+T+ G++A GD PM H + + + + G + IP ++
Sbjct: 298 EHLRTSAEGVWAAGDCAGTPMFTHASWSDFRIIRAQLTGASLDEATTTTKGRTIPYAVFA 357
Query: 383 SPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKT-NGETEGFVKVLSDKTTDVILGTH 441
+PE+ +G +E + ++ G ++ K P A RAKT EGF K + D T ILG
Sbjct: 358 TPELARIGLSEGEAREAGLDVRIAKVPTAAIPRAKTMRYAGEGFWKAIVDANTHQILGAT 417
Query: 442 IIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALR 482
+IGP E+I +A G E + + AHPT E L+
Sbjct: 418 LIGPNVSEVITAVHVAMAGGLTYEQLRFLPIAHPTMGEGLQ 458
>UniRef50_A3ESJ6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide dehydrogenase component; n=1;
Leptospirillum sp. Group II UBA|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dihydrolipoamide dehydrogenase component -
Leptospirillum sp. Group II UBA
Length = 461
Score = 196 bits (477), Expect = 1e-48
Identities = 137/455 (30%), Positives = 210/455 (46%), Gaps = 14/455 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL+VIG+G G AA AA LG V+ VEK P GG C+ GC+PSKALL +H++H+ K
Sbjct: 6 DLLVIGAGSAGRYAARSAASLGKSVLLVEKGP-FGGLCILKGCMPSKALLRPAHVFHLMK 64
Query: 93 HDFKQRGIET-GEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNK-VNLVKGVGTIVAPNK 150
H K G+ G V D ++ K ++ + + + L+ G + P
Sbjct: 65 HRLKDLGLSVDGSVKADIPAIVRMKNAMIREMAEDARKTIEATPGITLLTGNFSFTGPQA 124
Query: 151 VEVHGEKGVETVNTKNILIASGSEV--TPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
G G V+ +IA+GS V PG+ +E+ I+TS L +E +P LV+G
Sbjct: 125 ----GLLGDTPVHFDKAVIATGSRVHVPAIPGL--EEEWILTSDDVLEMEEIPSSTLVLG 178
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
G +GLELG LG+DVT + D ++A+ L+ +G+ LG +
Sbjct: 179 GGPVGLELGQYLSCLGSDVTLAD-TNQNWHPQTDPQLAREYLGTLASRGLNIHLGIRAEK 237
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
++ G+ K G + D VL++ GRRP T GL L + G I V+
Sbjct: 238 FER-GAGEKPFFSFHADGKNHKVPFDRVLLATGRRPDTSGLNLPAAQVQTTRHGHIQVDA 296
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEG-IKGMPVHFNYDAIPSVIYTSPEVG 387
+T+ I+A GDV + + A G + + +PV +P I+T PE
Sbjct: 297 FLRTSNHSIFAAGDVTGILPVLNLATFHGEMAGRNAVLPVPVTVREPVVPVAIFTDPEYA 356
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
G TE + K G+ F +A ETEG +K++ + ILG + GPG
Sbjct: 357 RAGLTESMAQARRIPVKTGRISFSDLGKAIVYRETEGGLKIVVHAKSREILGVELFGPGA 416
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALR 482
+L++ A + A + + H HPT +E +
Sbjct: 417 SDLVHTVATAMHFHATIDQYQEILHIHPTFSEIFK 451
>UniRef50_Q2NDS9 Cluster: Mercuric reductase, putative; n=2;
Erythrobacter|Rep: Mercuric reductase, putative -
Erythrobacter litoralis (strain HTCC2594)
Length = 472
Score = 195 bits (476), Expect = 2e-48
Identities = 146/462 (31%), Positives = 229/462 (49%), Gaps = 24/462 (5%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D++VIG G G AA A G+KV +E +GG CLN GC+PSKAL+ + A+
Sbjct: 6 DVIVIGGGAAGLTAAGGCALFGLKVALIEGHK-MGGECLNNGCVPSKALITAAKRAAEAR 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTG-GIAMLFQKNKVNLVKGVGTIVAPNKV 151
K+ G+E ++ + + A+ + A F++ +++ + V
Sbjct: 65 KQ-KRFGVELAAPNVEWSGVHTHIHRAIAEIEPHDSAERFEEMGCEVIQDWARVTGKQSV 123
Query: 152 EVHGEKGVETVNTKNILIASGS--EVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
E+ G T+ I+IA+GS V P PG+ D +T+ LE+ P +++IG
Sbjct: 124 EIGGR----TLTAPRIVIATGSGPSVPPIPGL--DAVPYLTNENIFDLEAQPDHLVIIGG 177
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
GVIG+E+ + RLG+ VT IE +G D + + +++ K+G+ F G K V
Sbjct: 178 GVIGMEMAQSFARLGSKVTVIEPGRPMG--RDDEDSVAVVMEVMKKEGVTFVQG-KAEKV 234
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
+ I V V+ N E + +LI++GR+ G GL+ +G+ L + G I V+ +
Sbjct: 235 EGRNGAITVHVD-----NGEQVSGSHLLIAVGRKARVSGFGLEDLGVELGNNG-IKVDER 288
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGI-VCVEGIKGMPVHFNYDAIPSVIYTSPEVGW 388
+T+V IYAIGD GP L H + EG V +E G+P +Y A+P YT PEV
Sbjct: 289 RRTSVKNIYAIGDCREGPRLTHVSGYEGSNVALEITLGIPTKVDYKALPWCTYTEPEVAQ 348
Query: 389 VGKTEEDLK-KEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
+G TE + K K G V K F N RA T G+T+G +KV+ +LG I+G
Sbjct: 349 IGLTEAEAKEKFGDKVTVVKEGFDHNERAITEGDTKGHMKVILKGKK--VLGASIVGKNA 406
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAY 489
GEL+ ++ + ++PT +E + A AA+
Sbjct: 407 GELLLPFSQTITGKSSTFAMGSAIVSYPTRSEITKAAAFAAW 448
>UniRef50_Q5ZY02 Cluster: Glutathione reductase; n=4; Legionella
pneumophila|Rep: Glutathione reductase - Legionella
pneumophila subsp. pneumophila (strain Philadelphia 1
/ATCC 33152 / DSM 7513)
Length = 454
Score = 195 bits (475), Expect = 3e-48
Identities = 140/456 (30%), Positives = 228/456 (50%), Gaps = 17/456 (3%)
Query: 29 THDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLY 88
T DL+V+G G GG +A++AAQ G KV +E++ LGGTC+N+GC+P K +++N+
Sbjct: 5 TKHFDLIVLGGGSGGIASAVRAAQYGAKVAVIEQNH-LGGTCVNLGCVPKK-IMYNASSI 62
Query: 89 HMAKHDFKQRGIET-GEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVA 147
H G D+K+++ + ++ L F ++K+ L++G G
Sbjct: 63 AETLHKSPDYGFFLENNAKLDWKRLVNKRNAYIERLRENYEKRFSQHKITLIQGKGIFHD 122
Query: 148 PNKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVI 207
+ + + ++I+IA+GSE P + K I S G SL +P K+ VI
Sbjct: 123 QSSITIDHT----IYQAEHIIIATGSEPA-LPAIN-GIKHAIDSDGFFSLTKLPAKVAVI 176
Query: 208 GAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVL 267
G+G IG+EL + LG++ T + + D + TL +I+ KQG+ K
Sbjct: 177 GSGYIGVELAGILNSLGSE-THLLMRGTRPLSRFDHMIGDTLMEIMQKQGICIHQNHKAQ 235
Query: 268 GVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVN 327
+ K + G E + DV++ ++GR+P T L LDK+ + +DD+G I V+
Sbjct: 236 AIHLHSDGRK-SILCQSGSIIE--NIDVIISAVGRKPRTGNLNLDKINVNMDDKGLILVD 292
Query: 328 NKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKG-MP-VHFNYDAIPSVIYTSPE 385
T+V GIYAIGDV + P L A G + I G P NYD I SV+++ P
Sbjct: 293 AFQNTSVKGIYAIGDVTNAPALTPVAIAAGRRLADRIFGNQPDACLNYDNICSVVFSHPP 352
Query: 386 VGWVGKTE-EDLKKEGR-AYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHII 443
G VG TE E ++K G+ K+ + F+ A + +T +K+++ + I+G H++
Sbjct: 353 SGSVGLTEHEAIEKYGKNKIKIYQTRFIPMYDALSIDKTPTAMKLVTLGKKEKIIGLHVV 412
Query: 444 GPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAE 479
G E++ +A + GA +D HPT AE
Sbjct: 413 GYSADEMLQGFGVAIKMGACKKDFDNTIAIHPTSAE 448
>UniRef50_Q5ZV78 Cluster: Mercuric reductase; n=5; Legionella
pneumophila|Rep: Mercuric reductase - Legionella
pneumophila subsp. pneumophila (strain Philadelphia 1
/ATCC 33152 / DSM 7513)
Length = 714
Score = 195 bits (475), Expect = 3e-48
Identities = 140/466 (30%), Positives = 225/466 (48%), Gaps = 18/466 (3%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
+ DL +IG G GG A +QLG+KVV VE +GG CLN GCIPSK+LL + ++
Sbjct: 246 NCDLAIIGGGAGGLSLASGCSQLGLKVVLVESGK-MGGDCLNYGCIPSKSLLAAAKTFYY 304
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAML-FQKNKVNLVKGVGTIVAPN 149
AKH G+ T + +F+++M++ + ++ ++ F+ V ++K VG + P+
Sbjct: 305 AKHA-THFGVHTEAIKINFQQVMQHVHQIIDNISEHDSVQRFESLGVQVIKQVGKFLNPD 363
Query: 150 KVEVHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVI 207
++ G + K ++A+GS + P PG+ D T+ L+ P+ ++VI
Sbjct: 364 TLQA----GDSIIKAKRFVVATGSSPFIPPIPGL--DAVSYFTNETIFDLKEQPEHLIVI 417
Query: 208 GAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVL 267
G G IG EL + LG+ VT +E L + D + L+ + + ++
Sbjct: 418 GGGPIGCELAQAFAMLGSKVTLLEGLNLL--PKDDPDCVAVLRTQMKSMSIVIHEQIEIT 475
Query: 268 GVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVN 327
+ T + V + + +LI+ GRR K L L+K G+ L +G + VN
Sbjct: 476 QINSHPDT-GISVCFEFQNTQFTITASHLLIATGRRANVKPLDLEKAGVKLTSKG-VEVN 533
Query: 328 NKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIK-GMPVHFNYDAIPSVIYTSPEV 386
QT+ IYA+GDV H A + + + I +P +Y AIP V YT PE+
Sbjct: 534 KYLQTSNKKIYALGDVTGLYQFTHMASYQASIVLRNIVFKLPSKVDYRAIPWVTYTDPEL 593
Query: 387 GWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPG 446
VG D K A ++ ++PF+ N RA+T G +K+++DK ILG I+GP
Sbjct: 594 AHVGIGVSDALKHPDA-QIIEWPFVDNDRAQTERSLNGKIKIITDKKAR-ILGVTIVGPH 651
Query: 447 GGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGK 492
GELI V+A V +PT +E + + Y+ K
Sbjct: 652 AGELILPWVMAIREKKNLRSFTDVIVPYPTLSEISKRVAGSFYAPK 697
>UniRef50_A6Q9K6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E3 component, dihydrolipoamide dehydrogenase;
n=1; Sulfurovum sp. NBC37-1|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, E3 component, dihydrolipoamide
dehydrogenase - Sulfurovum sp. (strain NBC37-1)
Length = 464
Score = 195 bits (475), Expect = 3e-48
Identities = 139/453 (30%), Positives = 224/453 (49%), Gaps = 16/453 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DLVVIG+GPGG AA+ AAQ G V+ V+K GG CL GCIPSK L + ++ + + K
Sbjct: 5 DLVVIGAGPGGTPAAMAAAQFGKSVLLVDKRDAPGGECLFEGCIPSKVLENAANRFEIFK 64
Query: 93 HDFKQRGIET-GEVTFDFKKMMEYKANAVKGLT-GGIAMLFQKNKVNLVKGVGTIVAPNK 150
+ K I+ G+ ++ ++E K +K + G + + + + +G +
Sbjct: 65 -EMKAFHIDVDGKEQIHWEAVLEDKKQILKRRSMGALKQVERFPNLEFRQGTARFTDTHT 123
Query: 151 VEVHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
++V GEK + + +IA+G+ + PF G K T+ +P+++ IG
Sbjct: 124 IDVDGEK----IAFDHAIIATGAAAFLPPFEGKGV--KNAWTNAEVFEKTELPEEITFIG 177
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
AG I EL ++ +LG +E I ID E A +Q+ + ++G+ +L G
Sbjct: 178 AGAISCELVQMFNKLGTKCHMLERGERILK-HIDEESAMVVQEKMIREGIDVQLNV-TFG 235
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
K EG V + G +VL+ +LI+ GR +GLGL+ VG+ D G I V+
Sbjct: 236 -KIEGEEGAFSVSYTQDGEAKVLETPYLLIATGRAANVEGLGLETVGVDFDRHG-IHVDE 293
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH-FNYDAIPSVIYTSPEVG 387
QTT IYA+GD GP AH A E + + I H + + V+++ P++
Sbjct: 294 TLQTTQENIYAVGDCTVGPKFAHWATYEAGIAIHNIFAPMKHKTDMSKLSWVLFSDPQIA 353
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG +E D +K+G V ++ + ++RA+ + EGF+K + +K + +I G I+
Sbjct: 354 SVGLSEADAQKQGMEVSVERYDYAVDARAQLDKAEEGFLKFVIEKKSGIIRGIQIVSEDA 413
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEA 480
L EA L A DV + H HPT E+
Sbjct: 414 SSLSGEASLIVANELKAMDVMKTIHPHPTLTES 446
>UniRef50_Q1K470 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region precursor; n=1;
Desulfuromonas acetoxidans DSM 684|Rep: Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
precursor - Desulfuromonas acetoxidans DSM 684
Length = 492
Score = 194 bits (474), Expect = 3e-48
Identities = 130/456 (28%), Positives = 225/456 (49%), Gaps = 17/456 (3%)
Query: 30 HDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYH 89
+D +LVV+G+G G V+A +A G +V VE+ +GG CLN GC+PSKAL+ ++HL
Sbjct: 15 YDYNLVVVGAGAAGLVSAYLSAAAGARVALVEQ-AQMGGDCLNRGCVPSKALIRSAHLAQ 73
Query: 90 MAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAM-LFQKNKVNLVKGVGTIVAP 148
+ G+ +V DF ++ME ++ + ++ +Q V G +++
Sbjct: 74 QMRQA-DHYGLPGQDVDVDFAQVMERVQQTIRTIEPHDSVERYQSLGVECFHGQAHLLSG 132
Query: 149 NKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
++V V G + T+ I++A+G+ D TS SL P++++V+G
Sbjct: 133 HEVAV----GDRVLTTRRIVLATGATPVVPELAGLDSVDYYTSDTIWSLRQKPRRLIVVG 188
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
G IG EL + RLG+ V + + D V + +Q++ +G++ L +
Sbjct: 189 GGPIGCELSQAFNRLGSQVVQVVHGERLLKRE-DRAVCELVQQVFHDEGVELCLNCDLQH 247
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
V ++ I + G + + D +L ++GR+P T+G G + +G +D RG + +
Sbjct: 248 VARQQDEIVLTCHV--GDEERTVHGDALLFAVGRQPMTQGFGFEVLGGTVDRRGALQADG 305
Query: 329 KFQTTVPGIYAIGDVIHGP-----MLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTS 383
+T+VP IY GDV+ GP M AH+A + + + + +P +
Sbjct: 306 TLRTSVPSIYCAGDVV-GPYQFTHMAAHQAATASLNALFD-RIWRRRVDVSLVPWTTFVD 363
Query: 384 PEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHII 443
PEV VG E+D ++ AY+V + + RA T+ T G+++VL+ D ILG I+
Sbjct: 364 PEVARVGLNEQDALRQKIAYEVTRLDYGELDRAVTDTTTPGWIQVLTVPGKDTILGVTIV 423
Query: 444 GPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAE 479
G G+ + E VLA + G + + H +PT AE
Sbjct: 424 GAHAGDCLAEFVLAMKNGLGLKKILATIHVYPTLAE 459
>UniRef50_A7JHZ5 Cluster: Soluble pyridine nucleotide
transhydrogenase; n=11; Francisella tularensis|Rep:
Soluble pyridine nucleotide transhydrogenase -
Francisella tularensis subsp. novicida GA99-3549
Length = 471
Score = 194 bits (474), Expect = 3e-48
Identities = 145/467 (31%), Positives = 221/467 (47%), Gaps = 31/467 (6%)
Query: 30 HDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKAL--LHNSHL 87
++ D+++IGSGPGG AA+KA + G KV +E D +GG C N G IPSKAL L
Sbjct: 8 YNYDIIIIGSGPGGEGAAMKATRNGQKVAIIEDD-AIGGGCNNWGTIPSKALRQLSREVW 66
Query: 88 YHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVA 147
Y+ DF + E+ K E K N F N++++ G + +
Sbjct: 67 YNKKNFDFPEMLDTAYEIVI---KQREIKRNR-----------FANNEIDVFYGFASFID 112
Query: 148 PNKVEVHGEKG-VETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLV 206
+K+++ + G E + K ++++GS + F +I+ S L L+ K +
Sbjct: 113 KHKIKISRKNGSTEIITAKKFILSTGSRPYHPDDIDFTHPRILDSDKLLELKDKNIKSIT 172
Query: 207 I-GAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILS-KQGMKFKLGT 264
I GAGVIG E S+ L V I + +D E+ +TL + Q +
Sbjct: 173 IYGAGVIGCEYASILGTLDIQVNLINTRNKLMSF-LDDEIIETLTNHFTVNQRINLIHNE 231
Query: 265 KVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALD-DRGR 323
+K G + + + + +++ D VL ++GR T GL LDK+G+ D RG
Sbjct: 232 TYKSIKARGDKVVTTLNSGR-----IIESDYVLFALGRSGNTNGLNLDKIGVEYDPQRGL 286
Query: 324 IPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEG-IVCVEGIKGMPVHFNYDAIPSVIYT 382
+ VN+ +QTT IYA+GDVI P LA A ++G I G + IP+ IYT
Sbjct: 287 VKVNDNYQTTQENIYAVGDVIGFPSLASSAFNQGRFAATHIIDGSCNDKLVEDIPTGIYT 346
Query: 383 SPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHI 442
PE+ +GKTEE L E Y+VG+ F +RA+ +G G +K+L K T ILG H
Sbjct: 347 RPEISCIGKTEEQLTAENIPYEVGRAYFKDLARAQISGSETGMLKILFHKETLEILGIHC 406
Query: 443 IGPGGGELINEAVLAQEYGAAAEDVARVCHA---HPTCAEALREANL 486
G E+I+ + + + +PT AEA R A +
Sbjct: 407 FGHRVSEIIHIGQAIKSMPGKHNTIRYFLNTTFNYPTMAEAYRIAGI 453
>UniRef50_Q7P4B5 Cluster: Mercuric reductase; n=3; Fusobacterium
nucleatum|Rep: Mercuric reductase - Fusobacterium
nucleatum subsp. vincentii ATCC 49256
Length = 459
Score = 193 bits (471), Expect = 8e-48
Identities = 143/462 (30%), Positives = 230/462 (49%), Gaps = 22/462 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTL-GGTCLNVGCIPSKALLHNSHLYHMA 91
DL+VIG G G + K KV +E++P + GGTC+NVGC+P+K+L+H++ + A
Sbjct: 6 DLLVIGWGKAGKTLSAKLGAKEKKVAIIEENPKMYGGTCINVGCLPTKSLVHSAKILSEA 65
Query: 92 KHDFKQRGIETGEVTFD---FKKMMEYKANAVKGLTG-GIAMLFQKNKVNLVKGVGTIVA 147
K + GI+ G+ +F FK+ M+ K L +L V++ G + ++
Sbjct: 66 K----KYGID-GDYSFKNNFFKEAMKKKEEMTTKLRNKNFGILDTNENVDIYNGRASFIS 120
Query: 148 PNKVEVHGEKGVETV-NTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLV 206
N+V+V E + I+I +GS D K I+ S G L L+ +PKK+L+
Sbjct: 121 DNEVKVVSSDNKEIILKADKIVINTGSVSRTLNIEGIDNKNIMVSEGILELKELPKKLLI 180
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
IGAG IGLE S + G++V+ +F S V D + AK +++IL K+ +KF T V
Sbjct: 181 IGAGYIGLEFASYFANFGSEVSIFQFDDSFL-VREDEDEAKIIKEILEKKDIKFFFKTSV 239
Query: 267 LGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPV 326
+ G+++K + G + + + D VLI++GR+P T LGL I L G I V
Sbjct: 240 KKFEDLGNSVKAI--CVQNGKEFIEEFDKVLIAVGRKPNTDNLGLKNTSIQLGKFGEILV 297
Query: 327 NNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYD---AIPSVIYTS 383
++ +T P ++A+GDV GP + + D+ + I G IP+ +
Sbjct: 298 DDYLKTDAPNVWAVGDVKGGPQFTYVSLDDFRIVFPQILGENNGRKLSDRILIPTSTFVD 357
Query: 384 PEVGWVGKTEEDLKKEGRAYKVGKFPFLANS--RAKTNGETEGFVKVLSDKTTDVILGTH 441
P VG E++ ++ G Y KF L N+ +A E EGF K+L ++ D I+G
Sbjct: 358 PPYSRVGINEKEAQRLGIKY-TKKFA-LTNTIPKAHVINEIEGFTKILINE-NDEIIGAS 414
Query: 442 IIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
I E+IN LA ++ + + HP E+L +
Sbjct: 415 ICHYESHEMINLLTLAINQKIKSKVLKDFIYTHPIFTESLND 456
>UniRef50_A3TUM1 Cluster: Glutathione-disulfide reductase; n=2;
Alphaproteobacteria|Rep: Glutathione-disulfide reductase
- Oceanicola batsensis HTCC2597
Length = 453
Score = 192 bits (468), Expect = 2e-47
Identities = 146/453 (32%), Positives = 217/453 (47%), Gaps = 16/453 (3%)
Query: 31 DADLVVIGSGPGGYVAA-IKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYH 89
D DL VIG G GG AA + A + G +V E+ GGTC+ GC+P K ++ S
Sbjct: 5 DYDLFVIGGGSGGVRAARVAAGETGARVALAEES-RYGGTCVIRGCVPKKLMVFASGYAE 63
Query: 90 MAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPN 149
M + D + G E G+ TF + + L G L V I +
Sbjct: 64 MVE-DARAYGWELGDGTFHWDTFRPKLDAELDRLEGIYKKLLDTPGVERFDQRARIRDAH 122
Query: 150 KVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
VE+ G T K+IL+A+G P + E I+ S LE++PK +LV+G
Sbjct: 123 TVEL--ADGT-TKTAKHILVATGGRPVR-PEMENAELGIV-SDDVFQLETLPKSVLVVGG 177
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
G I E + +G +VT I G D E + + ++ +G+ GT +L +
Sbjct: 178 GYIACEFACILNGMGVEVTQYYRGAQILR-GFDDEARGLVAEEMNAKGVDIHCGTNLLEM 236
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
++EG I V A G++ V D V+ + GRRP T LGL++ G+ L RG + V++
Sbjct: 237 RREGDGIWVK---ATNGSERVFD--KVIFATGRRPNTDDLGLEEAGVELGRRGEVVVDDY 291
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPEVGW 388
+T+VP IYAIGDV L A EG+ VE + +G P +++ IP+ I+T PE+G
Sbjct: 292 SRTSVPSIYAIGDVTDRANLTPVAIREGMAFVETVFRGNPTKPDHELIPTAIFTQPEMGT 351
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VG +EE +E +V F +K++ + T +LG HI+ P G
Sbjct: 352 VGLSEE-AAREQEPIEVYATSFRPMQTVFAGRPDRVMMKLIVSRETRRVLGCHIVAPQAG 410
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
E+I A +A + GA ED R HPT AE +
Sbjct: 411 EMIQLAGIAVKMGATKEDFDRTVAVHPTMAEEI 443
>UniRef50_Q2VHK2 Cluster: Oxidoreductase; n=11; Lactobacillales|Rep:
Oxidoreductase - Lactococcus lactis
Length = 449
Score = 192 bits (467), Expect = 2e-47
Identities = 133/456 (29%), Positives = 223/456 (48%), Gaps = 23/456 (5%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTL-GGTCLNVGCIPSKALLHNSHLYH 89
D +V+G G GG A + G VV +E+ + GGTC+N+GCIPSK L+ N
Sbjct: 5 DVKNIVVGFGKGGKTLAKFLSGKGESVVVIEQSTLMYGGTCINIGCIPSKFLIVNGEKGL 64
Query: 90 MAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPN 149
+++ + TG + M+ +A A + G A +++ ++ G ++A
Sbjct: 65 KFTEASEKKAMLTGNLNLKNYHMIADEATA--EVIDGKAKFVSDHEIEVMDAEGEVIA-- 120
Query: 150 KVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
++ GE+ +NT + + P PG+ D + ++TST + L+ +P+ + +IG+
Sbjct: 121 --QLIGER--IFINT-----GATPVLPPIPGLV-DSRNVVTSTELMDLKQLPEHLTIIGS 170
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
G IGLE S++ G+ VT ++ + D +++K ++ L +G+ FKLG K+ +
Sbjct: 171 GYIGLEFASMFASYGSKVTVLDIFDNFLPRD-DEDISKLVRSDLESRGIIFKLGVKIDAI 229
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
I K G K + D +L++ GR+P T GLGL+ I L RG I VN+K
Sbjct: 230 TDNSVEI-----INKEGKKVSILSDKILVATGRKPNTAGLGLENTNIQLGQRGEIVVNDK 284
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDA--IPSVIYTSPEVG 387
+TTV ++A+GDV G + + D+ + + G D +P+ ++ +P +
Sbjct: 285 LETTVQNVWALGDVHGGLQFTYTSLDDFRIVSNNLYGDGKRSLSDRKNVPTSVFITPALS 344
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG E+D K G Y++ K A ++ +++G +K L D TD ILG I
Sbjct: 345 KVGLNEKDAKAAGIDYRLFKLAATAIPKSAVLNQSKGLLKALVDPETDKILGITIYAEES 404
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
E IN LA E G + + HPT EAL +
Sbjct: 405 YETINLVSLAIEVGLPYTLLRDKIYTHPTMTEALND 440
>UniRef50_UPI000023D207 Cluster: hypothetical protein FG05450.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG05450.1 - Gibberella zeae PH-1
Length = 478
Score = 191 bits (466), Expect = 3e-47
Identities = 141/478 (29%), Positives = 229/478 (47%), Gaps = 32/478 (6%)
Query: 27 ATTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSH 86
AT +DA ++IGSG G A A G K +E+ LGGTC+NVGC P+K ++ +
Sbjct: 2 ATYYDA--IIIGSGQSGNPVAKAFANAGHKTAVIERT-ALGGTCVNVGCTPTKTMIASGR 58
Query: 87 LYHMAKHDFKQRGIETGEVTF--DFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGT 144
+MA+ K G+ G F D ++ + K V+ G V+++ G G+
Sbjct: 59 AAYMARRG-KDYGVHAGNGNFEIDMARVRQRKRAIVEQWNSGSVRGLNAAGVDVIMGEGS 117
Query: 145 IVAPNKVEVH-GEKGVETVNTKNILIASGS-----EVTPFPGVTFDEKQIITSTGALSLE 198
V K++V + G + V+ I I G +++ GV + +++ ST + L+
Sbjct: 118 FVGDKKLKVVLNDGGEKEVSADKIFINVGERPLRPDISGLDGV--EPARVLDSTSIMELD 175
Query: 199 SVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGM 258
+VP+ ++V+G G IGLE G +++RLG++VT I+ + D +VA+ L IL + G+
Sbjct: 176 AVPEHLVVLGGGYIGLEFGQLFRRLGSEVTVIQRAKQL-VPHEDPDVAECLYDILQQDGL 234
Query: 259 KFKLGTKVLGVKKEGST---IKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVG 315
L + V V + V+V+ A G +V +L++ GR P T L L +VG
Sbjct: 235 TVYLSSTVNSVSASTDSKMPFTVNVQTA-NGQTDVAGSH-ILLAAGRVPNTDRLNLSEVG 292
Query: 316 IALDDRGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDA 375
I +G + V++K QT+ +YA+GD G H + D+ + + + A
Sbjct: 293 IKTTSKGHVVVDDKLQTSASNVYALGDCHGGAAFTHISYDDSRIIRTNLLPKTMASTTPA 352
Query: 376 IPS------------VIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETE 423
+P+ V+YT P++G VG DL R K+ K P +RA E
Sbjct: 353 MPTTQSSTSRVLTPYVMYTDPQLGHVGLHARDLFNSKREVKIAKMPMSYVARALETAEPR 412
Query: 424 GFVKVLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
G +K + T ILG +G GGE+++ A D+ +AHPT AE+L
Sbjct: 413 GMMKATVEAKTGEILGFTCLGLEGGEIMSIVQTAMMGNLKWWDLEAAVYAHPTLAESL 470
>UniRef50_A5EH40 Cluster: Putative mercuric reductase protein; n=1;
Bradyrhizobium sp. BTAi1|Rep: Putative mercuric
reductase protein - Bradyrhizobium sp. (strain BTAi1 /
ATCC BAA-1182)
Length = 477
Score = 191 bits (466), Expect = 3e-47
Identities = 139/474 (29%), Positives = 233/474 (49%), Gaps = 26/474 (5%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
+ D+ VIG+G G A A+ G++ V +E+ +GG CLN GC+PSKALL + H
Sbjct: 6 NCDVCVIGAGAAGLSVAAGTARFGLRTVLIER-ARMGGECLNTGCVPSKALLSAAKAAHQ 64
Query: 91 AKHDFKQRG-IETGEVTFDFKKMMEYKANAVKGLTG-GIAMLFQKNKVNLVKGVGTIVAP 148
+ F+ G +E DF + + + + A F+ V ++ V
Sbjct: 65 -RETFRPPGSLELTSGPIDFAGVKDGVQAVIDAIAPHDSAERFEAMGVAVIADTAQFVDA 123
Query: 149 NKVEVHGEKGVETVNTKNILIASGS-EVTP-FPGVTFDEKQIITSTGALSLESVPKKMLV 206
++ G + + +IA+GS V P PG+ D +++T+ L P +++
Sbjct: 124 RTLKA----GQRRITARWFVIATGSMAVIPAIPGL--DASKVLTNDSIFQLRERPDHLVI 177
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
IGAG IG+E+ ++RLG VT I+ + + V + E+ L+ + + G+ G +
Sbjct: 178 IGAGPIGVEMAIAHRRLGCQVTVIDRASML--VNDEPELVAMLRDRMQQDGITLVEGADL 235
Query: 267 LGV--KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRI 324
+ V +K+G + +D+ GG ++ + C V ++ GR P GLGL+ G++ D +G I
Sbjct: 236 IAVDHRKDGLAVSLDL----GGARQTITCSHVFVAAGRSPVVDGLGLEAAGVSYDRKG-I 290
Query: 325 PVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIK-GMPVHFNYDAIPSVIYTS 383
V+ + +T+ I+A+GDVI GP H A + V V + +P NYDA+P V ++
Sbjct: 291 AVDRRLRTSQRHIFALGDVIDGPRFTHVAGHQAGVVVRNLAFRLPAKVNYDALPWVTFSD 350
Query: 384 PEVGWVGKTEEDLKKEGRAYKVGKFPFL-ANSRAKTNGETEGFVKVLSDKTTDVILGTHI 442
PE+ VG TE ++E +F L N RA T G +KV++ + ILG I
Sbjct: 351 PELAHVGLTEARARREMDGDVAVQFVRLEKNDRAVAEHRTNGAIKVVTGR-GGRILGASI 409
Query: 443 IGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 496
+ P GE+I LA + + ++ + +PT E + A A +PI F
Sbjct: 410 LAPAAGEMIGLWCLAVQRRMTMKAISDLMLPYPTMGEIAKAA--AGQHFEPIVF 461
>UniRef50_Q5P1X0 Cluster: Putative uncharacterized protein; n=1;
Azoarcus sp. EbN1|Rep: Putative uncharacterized protein
- Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 360
Score = 190 bits (464), Expect = 5e-47
Identities = 102/331 (30%), Positives = 176/331 (53%), Gaps = 3/331 (0%)
Query: 156 EKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVIGLE 215
E G V + +++ +G+ P E+ I S L +P +++V+G G IGLE
Sbjct: 31 EVGAREVLAREVVLDTGTRSAVPPIENLHEQDFINSENWLDRPQLPDRLVVVGGGYIGLE 90
Query: 216 LGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKEGST 275
+G Y+RLG++VT ++ I G D +VA LQ++L + + F++G K V+K +
Sbjct: 91 MGQFYRRLGSEVTIVQHGAQIAGHE-DRDVADALQQLLEDERIGFRIGAKATRVRKLAAG 149
Query: 276 IKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQTTVP 335
+ + ++ G E L+ + +++GR+P T GL+ +G+A DD G I V+++ +T V
Sbjct: 150 LALTLDTDAGC--EELEASDLFVAVGRQPNTDEQGLETIGLAPDDEGIIDVDSRLRTEVA 207
Query: 336 GIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGKTEED 395
G++A+GD+ G M H + D+ + + G +P I+T P++G VG TE++
Sbjct: 208 GVWAVGDIRGGAMFTHTSWDDYRIVASQVLGDGSRTLDRVVPYAIFTEPQLGRVGMTEDE 267
Query: 396 LKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELINEAV 455
++ GR +VG+F N +A+ GET GF+KV+ D + +LGT ++ EL+ V
Sbjct: 268 ARRAGRNIRVGRFDMAGNGKARELGETRGFIKVVVDADSCKLLGTAVLAEDAAELVQLYV 327
Query: 456 LAQEYGAAAEDVARVCHAHPTCAEALREANL 486
+ A + HPT AEA + L
Sbjct: 328 ILMNVDAPYTVIENAVLIHPTLAEAAQSVFL 358
>UniRef50_Q4SQZ1 Cluster: Chromosome 11 SCAF14528, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 11
SCAF14528, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 629
Score = 190 bits (463), Expect = 7e-47
Identities = 163/532 (30%), Positives = 251/532 (47%), Gaps = 57/532 (10%)
Query: 14 RSGSLVRIATRQYATTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKD-PT------- 65
+ GSL ++ Q +D DL+VIG G GG + +AA LG KV+ ++ PT
Sbjct: 99 KDGSLQQLLNGQNEA-YDYDLIVIGGGSGGLACSKEAALLGKKVMVLDYVVPTPKGTSWG 157
Query: 66 LGGTCLNVGCIPSKALLHNSHLYHMAKHDFKQRGIETGE-VTFDFKKMMEYKANAVKGLT 124
LGGTC+NVGCIP K L+H + L A D ++ G E E VT +++ M + + L
Sbjct: 158 LGGTCVNVGCIPKK-LMHQTALLRTAIQDARKFGWEFDEAVTHNWETMKTAINDYIGSLN 216
Query: 125 GGIAMLFQKNKVNLVKGVGTIVAPNKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFD 184
G + + VN V V P+K++ ++G ET T + + E + GV D
Sbjct: 217 WGYRVSLRDKNVNYVNAYAEFVDPHKIKATNKRGKETFYTAARFVLATGERPRYLGVPGD 276
Query: 185 EKQIITSTGALSLESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGE 244
++ ITS SL P K LVIGA + LE G LG DVT + + SI G D +
Sbjct: 277 KEYCITSDDLFSLPYCPGKTLVIGASYVALECGGFLAGLGLDVTVM--VRSILLRGFDQD 334
Query: 245 VAKTLQKILSKQGMKF----------------KLGTK-VLGVKKEGSTIKV----DVEAA 283
+A + + + G+KF +G + VL V+K S V ++EA
Sbjct: 335 MANRAGQYMEEHGVKFLRKYVPVQVGGPRKRAGVGARLVLHVQKSSSLTSVWQIEELEAG 394
Query: 284 KGGNKEVL------------DCDVVLISIGRRPYTKGLGLDKVGIALDDR-GRIPVNNKF 330
G +V + + VLI++GR T +GLDKVG+ ++ + G+IPVN++
Sbjct: 395 TPGRLKVTAKSTESDEIIEEEYNTVLIAVGRNACTDKIGLDKVGVKVNPKNGKIPVNDEE 454
Query: 331 QTTVPGIYAIGDVIHGPM-LAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPEVGW 388
QT+VP IYAIGD++ L A G + + G V +Y +P+ ++T E G
Sbjct: 455 QTSVPHIYAIGDILEEKWELTPVAIQAGRLLARRLYGGSKVKCDYVNVPTTVFTPMEYGA 514
Query: 389 VGKTEEDL-----KKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDK-TTDVILGTHI 442
G +EE ++ + +P + N + + K++ +K + ++G H
Sbjct: 515 CGLSEERAVGLYGQENIEVFHTQFWPLEFTVPGRDNNKC--YAKIICNKLDSGRVVGFHY 572
Query: 443 IGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPI 494
+GP GE+ A + GA E + HPTCAE + SGK I
Sbjct: 573 LGPNAGEVTQGFSAAMKCGATKEQLDGTIGIHPTCAEIFTTLEVTKSSGKSI 624
>UniRef50_Q6AQZ1 Cluster: Related to mercuric reductase; n=17;
Proteobacteria|Rep: Related to mercuric reductase -
Desulfotalea psychrophila
Length = 716
Score = 190 bits (463), Expect = 7e-47
Identities = 140/467 (29%), Positives = 230/467 (49%), Gaps = 24/467 (5%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
D +L+VIG+G G V+A A L KV VE +GG CLN GC+PSKAL+ ++ + H
Sbjct: 235 DRNLIVIGAGAAGLVSAYIATTLKAKVTLVEA-AEMGGDCLNYGCVPSKALIKSAKVAHH 293
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAM-LFQKNKVNLVKGVGTIVAPN 149
++ K G++ E++F F+++M + + ++ + V ++ G ++ P
Sbjct: 294 IRNGDKY-GLDAVELSFSFRRVMARVHRIIATIEPHDSVERYTDLGVEVLCGYARLLDPW 352
Query: 150 KVEVHGEKG-VETVNTKNILIASGSE--VTPFPGVTFDEKQIITS----TGALSLESVPK 202
VEV + G + ++ ++IA+G+ + P PG+ D +T+ +L+ P+
Sbjct: 353 TVEVKLKSGETRRLTSRAVIIATGAGPFIPPLPGL--DAVDYLTNETLWNAFANLDEAPR 410
Query: 203 KMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKL 262
++LV+G G IG EL RLG++V I+ + D + A ++ L G+
Sbjct: 411 RLLVLGGGPIGCELSQALARLGSEVWQIQRGARLLPRE-DADAAAIVEASLGADGVHVLT 469
Query: 263 GTKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRG 322
G L ++ G + VE G + L D ++ ++GR KG GL+++GI + +
Sbjct: 470 GHTALRCERAGEEKYIVVEHE--GQELRLAFDALICAVGRVARLKGYGLEELGIPV--KR 525
Query: 323 RIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVE-----GIKGMPVHFNYDAIP 377
+ N QT P I+A GDV H A + V GIK V +Y IP
Sbjct: 526 TVLTNEYLQTLYPNIFAAGDVAGPYQFTHTAAHQAWYAVVNALFGGIKKFKV--DYSVIP 583
Query: 378 SVIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVI 437
+ PEV VG E++ + G +V ++ RA T+G EGF+K+L+ D I
Sbjct: 584 WTTFVDPEVARVGLNEQEAAERGVDVEVTRYDLDDLDRAITDGVREGFIKILTVPNKDRI 643
Query: 438 LGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
LG I+G G+L+ E VLA ++G + H +PT AEA + A
Sbjct: 644 LGVTIVGEHAGDLLAEFVLAMKHGLGLNKILSTIHTYPTLAEANKYA 690
>UniRef50_Q4A6P9 Cluster: Putative mercuric reductase; n=1;
Mycoplasma synoviae 53|Rep: Putative mercuric reductase
- Mycoplasma synoviae (strain 53)
Length = 459
Score = 189 bits (461), Expect = 1e-46
Identities = 146/464 (31%), Positives = 222/464 (47%), Gaps = 23/464 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTL-GGTCLNVGCIPSKALLHNSHLYHMA 91
D+++IG G GG A K KV +EKDP + GGTC+NVGC+P+K+ H SH++ +
Sbjct: 5 DVIIIGWGKGGKTLANKLGLSNKKVAIIEKDPKMVGGTCINVGCLPTKSYTHYSHVFVES 64
Query: 92 KHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNK-VNLVKGVGTIVAPNK 150
+ ETG+ + K +++K VK L L KNK V++ G ++ +
Sbjct: 65 SKLGYKTSYETGKKAY--VKTLKHKLEFVKKLNQKNFELLNKNKNVDIYMGSAKFLSDYE 122
Query: 151 VEVH--GEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIIT-STGALSLESVPKKMLVI 207
VEV+ K + KNI+I +GS + + + S L+L ++PKK+LV+
Sbjct: 123 VEVNLNSNKKKVKLTAKNIIIGTGSVSRKLNIEGAAKSRFVKYSNDILNLRTLPKKLLVV 182
Query: 208 GAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVL 267
GAG IGLE S + G VT ++ D E +K + L KQG+KF+ T
Sbjct: 183 GAGFIGLEFASYFANFGTQVTVAQYNNDFMP-NEDKEDSKFILDTLKKQGIKFEFNTTCE 241
Query: 268 GVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVN 327
K S ++V + KE D VLIS GR P T LGL+ I + D I VN
Sbjct: 242 KFKDLKSQVQVSLSNKTKKYKEKFDA--VLISAGRIPNTLNLGLENTKIKVLDNKAIEVN 299
Query: 328 NKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYD---AIPSVIYTSP 384
QT V GIYAIGDV GPM + + D+ + + + + N D +P+ ++ P
Sbjct: 300 KYLQTNVKGIYAIGDVKGGPMFTYISLDDYRIVSDQLLKTKKNRNLDNRPLVPTNVFIRP 359
Query: 385 EVGWVG---KTEEDLKKEGRAYKVGKFPFLANS--RAKTNGETEGFVKVLSDKTTDVILG 439
VG K ++L +G K L +S +A E EGF K++ +K +I G
Sbjct: 360 SFARVGLNLKQAKELNLQGCYAKT----ILTSSIPKAHVINELEGFNKLIFNKQNQLI-G 414
Query: 440 THIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
+ E++N L + E++ ++HP E L +
Sbjct: 415 VSLFSYVAHEIVNVFSLMIQNKMTFEEIKDYIYSHPVYTEMLND 458
>UniRef50_A7D615 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
- Halorubrum lacusprofundi ATCC 49239
Length = 496
Score = 189 bits (461), Expect = 1e-46
Identities = 145/480 (30%), Positives = 224/480 (46%), Gaps = 31/480 (6%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D +VIGSG G VA A Q G V VE+ LGGTCLN GCIPSK LL+++ + +
Sbjct: 14 DFLVIGSGSGLDVANAMAGQ-GNSVAIVEEG-RLGGTCLNRGCIPSKKLLYHADVMKTVQ 71
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAM-LFQKNKVNLVKGVGTIVAPNKV 151
+ I+ DF +++ V G + I L + +L G G V V
Sbjct: 72 RA-GEFDIDAEVNGVDFAEIVRTVNEDVSGSSESIRKGLTSSDAHDLFSGTGRFVDDRTV 130
Query: 152 E-VHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
E V G+ T+ +LIA+G+ + P G+ ++ +TST AL LE+ P ++++G
Sbjct: 131 EIVDGDDEGATLRADTVLIATGTRPSIPPIDGI--EDVDYLTSTEALRLETAPDHLVIVG 188
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
G I ELG + G+DVT + ++ D V + + + + G + +
Sbjct: 189 GGYIAAELGHFFGTFGSDVTIVGRRENLLPEA-DEAVGEAFTDRYADRFDVYS-GYEAVA 246
Query: 269 VKKEGSTIKVDV------EAAKGGNKEV----------LDCDVVLISIGRRPYTKGLGLD 312
+ G + V+ E+ + G + V + D +L++ GRRP T L LD
Sbjct: 247 ADESGGEVTVEARPYPEAESVRAGGETVGAPEDAEDVTVAGDALLVAAGRRPNTDALNLD 306
Query: 313 KVGIALDDRGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKG-MPVHF 371
G+ D G + + QT G++A+GDV+ +L H A E + + G P
Sbjct: 307 ATGVETDADGFVETDEYLQTDAEGVWALGDVVGEYLLKHSANHEARAVIRNLLGDEPEPV 366
Query: 372 NYDAIPSVIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSD 431
+Y A+P ++ SPEV VG E+DL++ Y + + +R EGFVKVL D
Sbjct: 367 DYSAMPFAVFASPEVAGVGAREQDLRESDAEYATRTYAYDETARGSAM-HAEGFVKVLID 425
Query: 432 KTTDVILGTHIIGPGGGELINEAVLAQEYGA-AAEDVARVCHAHPTCAEALREANLAAYS 490
+ I G HI+GP LI E V+A G+ D+ H HP +E + A +S
Sbjct: 426 LDGN-IEGCHIVGPEASNLIEEVVVAMTAGSGTVADIRDAVHIHPALSEVVDRAFSGQFS 484
>UniRef50_Q01WF2 Cluster: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase; n=1; Solibacter
usitatus Ellin6076|Rep: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase - Solibacter
usitatus (strain Ellin6076)
Length = 468
Score = 189 bits (460), Expect = 2e-46
Identities = 140/463 (30%), Positives = 221/463 (47%), Gaps = 21/463 (4%)
Query: 29 THDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLY 88
T DL+ IGSGP G A AA G + VE+ GGT G P+K L + LY
Sbjct: 2 TDTYDLIAIGSGPAGESATELAAFFGHRCAVVERARP-GGTVTTTGGAPTKTL-REAALY 59
Query: 89 HMAKHDFKQRGIETG---EVTFD-FKKMMEYKANAVKGLTG-GIAMLFQKNKVNLVKGVG 143
D GI+ EV + +K + + ++ +TG IA KN V+ ++G
Sbjct: 60 FSGLVDGDVYGIKISTPPEVATEVIRKRTWHVCDLLQKVTGENIA----KNNVDYIQGAA 115
Query: 144 TIVAPNKVEVHGEKGVETVNTKNILI-ASGSEVTPFPGVTFDEKQIITSTGALSLESVPK 202
+ KV V G+ G N+L+ A+GS P + FD + + L VPK
Sbjct: 116 RLEGDGKVMVTGDDGSRRRLRANVLLLATGSRPRRPPNIPFDLAGVCDTDTILQRGRVPK 175
Query: 203 KMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKL 262
+L++G G +G+E ++ LGA VT + + + +DGE+ + ++++ G++
Sbjct: 176 DILIVGGGPVGVEFATIAHALGAKVTLADRGNRLMSM-MDGEITECMEELFRTWGIRVLF 234
Query: 263 GTKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRG 322
G+ V + +++ + E L D VL + GR P T LGLD G+A+D RG
Sbjct: 235 GSTCNSVVAKDDALEITMSTG-----ERLSPDTVLFAAGRVPNTGDLGLDAAGVAMDARG 289
Query: 323 RIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIP-SVIY 381
RI V+ +F+T+ G+YA GDV+ GP LA A ++G V + G+P D P S +Y
Sbjct: 290 RIVVDQQFRTSAEGVYAAGDVL-GPTLASIAMEQGRVAICHAFGIPFEGIVDPAPVSAVY 348
Query: 382 TSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTH 441
PEV G+TEE+ ++ G Y+VG+ R G G +K++ K ++G H
Sbjct: 349 GMPEVSGAGRTEEECREMGVDYEVGRADLARTPRGAIAGR-GGRLKLIFQKEDRRLIGVH 407
Query: 442 IIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
IG E++ + G +A + PT + A + A
Sbjct: 408 CIGDIASEIVGIGQMTIRCGGTIHTIANMSFNTPTYSYAYKYA 450
>UniRef50_A6SWJ7 Cluster: Mercury(II) reductase; n=50; Bacteria|Rep:
Mercury(II) reductase - Janthinobacterium sp. (strain
Marseille) (Minibacterium massiliensis)
Length = 474
Score = 189 bits (460), Expect = 2e-46
Identities = 128/462 (27%), Positives = 215/462 (46%), Gaps = 10/462 (2%)
Query: 22 ATRQYATTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKAL 81
AT T D ++IG+G A + GM++ +E+ ++GGTC+N GC P+K +
Sbjct: 10 ATTSGKQTEIFDAIIIGTGQAAPALANRLTASGMRIAVIERS-SVGGTCVNTGCTPTKTM 68
Query: 82 LHNSHLYHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIA-MLFQKNKVNLVK 140
+ ++++ MA + + D K + V+ G+ + L++
Sbjct: 69 VASAYVARMAARAAEYGVVLHHPPAIDMKAIKARVDKIVQTDRVGLENWMTGMPGCTLIR 128
Query: 141 GVGTIVAPNKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESV 200
G + N+V V + + I I G V + +T+T ++L+ V
Sbjct: 129 GHARFESGNEVCVDDRR----IKANKIFINVGGRAFIPDAVGLENISYLTNTDMVALDIV 184
Query: 201 PKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKF 260
P ++++G IGLE +++R G+ VT IE + + D EV+ ++ ILS + +
Sbjct: 185 PSHLIIVGGSYIGLEFAQMFRRFGSSVTVIERGSRLIARE-DEEVSAQIKDILSNEDISI 243
Query: 261 KLGTKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDD 320
L + L +K + + V+V+ K + +LI++GRRP T LGLDK GI D
Sbjct: 244 MLDAEELQFQKHAAGVAVNVKCKNDWKK--ISGSHLLIAVGRRPNTDDLGLDKAGIETDT 301
Query: 321 RGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPS-V 379
G I V+ + +TT G++A+GD H A ++ + + D IP+
Sbjct: 302 MGYITVDEQLRTTANGVWALGDCNGRGAFTHTAYNDFEIVAANLLDGETRCVSDRIPAYA 361
Query: 380 IYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILG 439
+Y P +G VG T KK GR +VG +RA GET+G ++V+ D T+ ILG
Sbjct: 362 LYIDPPLGRVGMTATQAKKAGRKIRVGTRQMTRVARAIEKGETQGSMRVVVDAETNEILG 421
Query: 440 THIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
I+GPGG E I+ + A + HPT +E +
Sbjct: 422 AAILGPGGDEAIHAILATMAAKAPYTQLTHTMAIHPTLSELI 463
>UniRef50_A3UIQ0 Cluster: Probable glutathione reductase; n=1;
Oceanicaulis alexandrii HTCC2633|Rep: Probable
glutathione reductase - Oceanicaulis alexandrii HTCC2633
Length = 449
Score = 189 bits (460), Expect = 2e-46
Identities = 143/458 (31%), Positives = 217/458 (47%), Gaps = 17/458 (3%)
Query: 29 THDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNS-HL 87
T +DL+V+G+G G AA A + G V VE +GGTC GC+P K L+ + +L
Sbjct: 2 TRHSDLLVLGTGNAGMAAAGVAQRAGKSVTLVESGD-VGGTCAIRGCVPKKVLVAAAANL 60
Query: 88 YHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVA 147
+A+ I GEV D+ +++ + V+G+ + LV G
Sbjct: 61 DAIARAS--DHAISVGEVKLDWPALIKRERTFVEGVPEMFRASITNRGMALVSGKAVFTG 118
Query: 148 PNKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVI 207
PN ++V GE T I+IA+GS+ P + TS L+LE++PK+++ +
Sbjct: 119 PNAIDVEGE----TYTADRIVIATGSKPAQLPIEGW--ALTATSDDLLTLETLPKEVVFV 172
Query: 208 GAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVL 267
G GVI LE + R GA VT +E + + +D ++ TL G+ + G V
Sbjct: 173 GGGVIALEFAHIMVRAGAKVTILEAASRVLP-RLDEDMVDTLVAHTRSLGVTIQTGVSVR 231
Query: 268 GVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVN 327
++++G+ + VE G L D+V+ GRRP + L L+ GI DRG I V+
Sbjct: 232 AIREDGA--RRAVEVVIDGETLSLSADLVVNGAGRRPAVEDLDLEAGGIR-SDRGHIEVD 288
Query: 328 -NKFQTTVPGIYAIGDVIHG-PMLAHKAEDEGIVCVEG-IKGMPVHFNYDAIPSVIYTSP 384
N T P +Y GD + P ++ A EG + E I +Y +IPS +YT P
Sbjct: 289 VNLRSLTNPSVYVAGDALAASPQMSPVASYEGRIAGENAINDAKESPDYSSIPSAVYTVP 348
Query: 385 EVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 444
+ VG E + G V AKT E F KVL D TD ILG H+ G
Sbjct: 349 AIASVGLDEAGAQAAGLEPVVKVNDMRDWRSAKTYAEQVAFAKVLIDPATDRILGAHLAG 408
Query: 445 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALR 482
G E+I+ LA + A ++A + +A+PT + L+
Sbjct: 409 HGAEEVIHLFTLAMKTQLTASELAAMTYAYPTFSSDLK 446
>UniRef50_A1AVW4 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=2;
sulfur-oxidizing symbionts|Rep: Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
- Ruthia magnifica subsp. Calyptogena magnifica
Length = 443
Score = 189 bits (460), Expect = 2e-46
Identities = 137/454 (30%), Positives = 218/454 (48%), Gaps = 21/454 (4%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
D D++ IG+G GG A +AA+ G K + +E +GGTC+NVGC+P K + ++ +
Sbjct: 4 DYDMIAIGAGSGGLSAVERAAEYGRKCLIIEVK-IIGGTCVNVGCVPKKVMWFAANTGSI 62
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
K+ K G E + F +KK+ + N +K +T QK ++ + G G +V N
Sbjct: 63 IKNA-KGFGFEVEQKGFSWKKLKVGRDNYIKSITNWYDSYLQKLGIDYIHGFGQLVDKNI 121
Query: 151 VEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
V V+G++ T +I S E P + E I TS +LE++PKK+ VIG G
Sbjct: 122 VSVNGKE-----YTAEYIILSSGEEPAVPHIEGSEYGI-TSDNFFALEALPKKVAVIGGG 175
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
IG+EL V LG++VT + G D + TL K S G+ T++ V
Sbjct: 176 YIGVELAGVLNALGSEVTLFCRADKLLR-GFDSMIQNTLDKDYSSHGITIHHNTQIDKVS 234
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
K T+ + A G D ++ ++GR P T+ LGL G+ D +G I + KF
Sbjct: 235 KN-KTLFTNQGAFTG-------FDTIIWAVGRNPMTQHLGLKVAGVKCDQKGFIQTD-KF 285
Query: 331 QTT-VPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPV--HFNYDAIPSVIYTSPEVG 387
QTT V I+A+GDV L A G + + H +Y+ I +V+++ P +G
Sbjct: 286 QTTNVDNIFALGDVTGRTSLTPVAIAAGRRLSDRLYNNMTDRHLDYNNIATVVFSHPPIG 345
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG TE ++ K+ K F + A +T +K++ + ++G HI+G G
Sbjct: 346 MVGLTEAQANEKFDKIKIYKSEFTPMADALLEHKTTTALKLVCAGDNEKVIGCHIMGHGA 405
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
E++ +A + G + HPT +E L
Sbjct: 406 DEILQGFAMAIKMGVTKKQFDDTIAIHPTISEEL 439
>UniRef50_Q8ZUT2 Cluster: Mercuric reductase; n=4;
Thermoproteaceae|Rep: Mercuric reductase - Pyrobaculum
aerophilum
Length = 467
Score = 188 bits (459), Expect = 2e-46
Identities = 148/476 (31%), Positives = 236/476 (49%), Gaps = 39/476 (8%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+VV+G G G AA+KAAQLG KV V P LGGTC+NVGC+PSK L+ + L A+
Sbjct: 3 DVVVLGGGSAGVAAAVKAAQLGAKVAVVNSGP-LGGTCVNVGCVPSKFLIRAAQLKRYAE 61
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGG-IAMLFQKNKVNLVKGVGTIVAPNKV 151
F +GI + +V F ++++ V+ L + + V++++G G + V
Sbjct: 62 RPFF-KGI-SAKVEVAFDALLQHMKEVVEELRREKYEEVLKYYDVDIIEGYGYLKDAKTV 119
Query: 152 EVHGEKGVETVNTKNILIASGSE--VTPFPGV--TFDEKQIITSTGALSLESVPKKMLVI 207
+V G V + I++A+G+ V PG+ T+ L+ +P ++ I
Sbjct: 120 KV----GEREVRGEKIIVATGARPRVPEIPGLKEAMARGMAFTNEEFFKLDHMPSSIVFI 175
Query: 208 GAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVA-KTLQKILSKQGMKFKLGTKV 266
G G I EL RLG +V I + +S + + E+A K ++++L+ +G++ + V
Sbjct: 176 GGGAIAAELSQALARLGIEVAVI-YRSSF--LKYEEEIASKFVEELLANEGVRL-IKAAV 231
Query: 267 LGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLG-LDKVGIALDDRGRIP 325
V+ G ++V GG+ + + + ++ GR P + LG L K+G G +
Sbjct: 232 TAVEIRGREVEV---RHSGGS---VRAEALFVAAGRAPNIEPLGGLLKLG----PNGGVL 281
Query: 326 VNNKFQTTVPGIYAIGDVIHG----PMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIY 381
VN + +T++PG+YA GDV G L + A +G+V G FN A+P V++
Sbjct: 282 VNERMETSLPGVYAAGDVTGGLEGARFLENAAARQGVVAAVNAMGGNAKFNPLAVPRVVF 341
Query: 382 TSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTT------- 434
T P V VG EED+ K G + P A + T G+T GF+K+ + T
Sbjct: 342 TDPAVASVGLREEDMIKGGIGCRCRAAPIEAVAAGWTKGQTTGFIKINTYPETWKVSVKR 401
Query: 435 DVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYS 490
I G ++ P ELIN +A + G ED+ + P+ EALR A LA Y+
Sbjct: 402 GKIAGALVVAPEAEELINVFAMAIQLGLTVEDLIEWLPSFPSYGEALRLAALAFYT 457
>UniRef50_Q58E89 Cluster: MGC84926 protein; n=7; cellular
organisms|Rep: MGC84926 protein - Xenopus laevis
(African clawed frog)
Length = 476
Score = 188 bits (458), Expect = 3e-46
Identities = 133/460 (28%), Positives = 231/460 (50%), Gaps = 18/460 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D +V+G G GG +A +AA+LG + VE LGGTC+NVGC+P K ++ N+ ++
Sbjct: 20 DYLVVGGGSGGLASARRAAELGARTAVVESSK-LGGTCVNVGCVPKK-IMWNAAMHSEYI 77
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK-- 150
HD G E +V F +K + E + V L QK ++ +++G + +
Sbjct: 78 HDHADYGFEIPDVKFTWKVIKEKRDAYVSRLNDIYQNNLQKAQIEIIRGNANFTSDPEPT 137
Query: 151 VEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQI-ITSTGALSLESVPKKMLVIGA 209
VEV+G+K + +ILIA+G + + + ITS G L +P++ +V+GA
Sbjct: 138 VEVNGQK----YSAPHILIATGGKPSMPSDAELPGASLGITSDGFFELTDLPRRSIVVGA 193
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
G I +E+ + LG+ + + + D ++ + L G++ +V V
Sbjct: 194 GYIAVEIAGILSALGSKASLLIRQDKVLRT-FDSIISSNCTEELENAGVEVWKYAQVKSV 252
Query: 270 KKEGSTIKVDVEAAKGGNKEVL----DCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIP 325
KK + ++++V+ + G K + D D +L +IGR P T+ LGL+ +G+ LD++G I
Sbjct: 253 KKSTTGLEINVQCSMPGRKPTVRTIQDVDCLLWAIGRDPNTEYLGLENLGLELDEKGHIV 312
Query: 326 VNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI-KGM-PVHFNYDAIPSVIYTS 383
V+ T+ G+YA+GDV +L A G + +G +Y+ IP+V+++
Sbjct: 313 VDEFQNTSRKGVYAVGDVCGRALLTPVAIAAGRKLSHRLFEGQEDSKLDYNNIPTVVFSH 372
Query: 384 PEVGWVGKTEED-LKKEGRA-YKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTH 441
P +G VG TEE+ + +GR KV F T +T+ +K++ + ++G H
Sbjct: 373 PPIGTVGLTEEEAVTAKGRENVKVYTTSFSPMYHVVTRRKTKCVMKLVCVGKEEKVVGLH 432
Query: 442 IIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
+ G G E++ +A + GA +D HPT +E L
Sbjct: 433 MQGLGCDEMLQGFAVAIKMGATKKDFDNTVAIHPTSSEEL 472
>UniRef50_Q5VGY1 Cluster: Dihydrolipoamide dehydrogenase; n=3;
Plasmodium|Rep: Dihydrolipoamide dehydrogenase -
Plasmodium falciparum
Length = 666
Score = 187 bits (456), Expect = 5e-46
Identities = 162/534 (30%), Positives = 256/534 (47%), Gaps = 86/534 (16%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPT-LGGTCLNVGCIPSKALLHNSHLYHMA 91
DL +IG G GG+ AAI A + +KV+ D +GGTC+NVGCIPSKALL+ ++ Y
Sbjct: 127 DLAIIGCGVGGHAAAINAMERNLKVIIFAGDENCIGGTCVNVGCIPSKALLYATNKYREL 186
Query: 92 KH---------------DFKQRGIETGEVT-----FDFKKMMEYKANAVKGLTGGIA--- 128
K+ + K IE ++ + K+ EY + + L GI+
Sbjct: 187 KNLDKLYYYGIHSNIFQNNKNTEIENNQLVSNSFQINITKLKEYTQSVIDKLRNGISHGF 246
Query: 129 --MLFQKNK--VNLVKGVGTIVAPNKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFD 184
+ F KN V ++ G ++ N ++ +K T KNI+IA+GS V D
Sbjct: 247 KTLKFNKNSEHVQVIYEHGQLLDKNTIK--SKKSGNTYKVKNIIIATGSVPNIPNNVEID 304
Query: 185 EKQIITSTGALSLESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGE 244
+K + TS A+ L + M +IG G+IGLE +Y LG+++T +E+ + + + ID +
Sbjct: 305 DKSVFTSDMAVKLVGLKNYMSIIGMGIIGLEFADIYTALGSEITFLEYSSELLPI-IDND 363
Query: 245 VAKTLQKI-LSKQGMKFKLGTKVLGVK--KEGSTIKVDVEAAKGGN----KEVLD----- 292
VAK +++ L + + + L T+V +K K + + + G + K + D
Sbjct: 364 VAKYFERVFLKNKPVNYHLNTEVKYIKASKNNNPVIIGYSHRTGNDDNEKKNMTDVKELY 423
Query: 293 CDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQTTV------PGIYAIGDVIHG 346
D L++ GR+P T+ LGL+K+ I + +RG + VN+ Q + I+ IGD
Sbjct: 424 VDSCLVATGRKPNTQNLGLEKLKIQM-NRGYVSVNDNLQVKMENNEIYDNIFCIGDANGK 482
Query: 347 PMLAHKAEDEGIVCVEGIKGMP---VHFN----------YDAIPSVIYTSPEVGWVGKTE 393
MLAH A + + ++ I+ V+ N Y IPSV YT+PE+ ++G TE
Sbjct: 483 QMLAHTASYQALKVIDFIEKKEKKNVNINVENNLSKPILYKNIPSVCYTNPELAFIGLTE 542
Query: 394 EDLK--------KEGRAYKVGKFPFLANS---------------RAKTNGETEGFVKVLS 430
++ K E YK N+ + N T G VK++
Sbjct: 543 KEAKVLYPDNVGVEISYYKSNSKILCENNISLNNNKKNNSYNKGQYNINDNTNGMVKIIY 602
Query: 431 DKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
+ T ILG I+G LI+EAVLA +A D+A + H+HPT +E L A
Sbjct: 603 KEDTKEILGMFIVGNYASVLIHEAVLAINLKLSAFDLAYMVHSHPTVSEVLDTA 656
>UniRef50_P48639 Cluster: Glutathione reductase; n=5; cellular
organisms|Rep: Glutathione reductase - Burkholderia
cepacia (Pseudomonas cepacia)
Length = 449
Score = 186 bits (452), Expect = 2e-45
Identities = 129/451 (28%), Positives = 211/451 (46%), Gaps = 15/451 (3%)
Query: 30 HDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYH 89
+D DL VIG+G GG AA AA G KV ++ ++ GGTC+ GC+P K L++ S Y
Sbjct: 4 YDFDLFVIGAGSGGVRAARIAAGHGAKV-AIAEEYRFGGTCVIRGCVPKKLLMYASQ-YG 61
Query: 90 MAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPN 149
D G + + + ++ K + L G L + V + KG I PN
Sbjct: 62 QGFEDAAGFGWHSAATSHSWTSLIAAKDAEIARLEGVYQRLIENANVEIFKGRAQIAGPN 121
Query: 150 KVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
+V V G +V+ + ILIA+G+ P V +ITS L P ++ +IG
Sbjct: 122 RVTVTGA----SVSARTILIATGARPV-MPPVA-GANLMITSDDVFDLPVGPPRIAIIGG 175
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
G I E ++ LG V + + + G D E+ + L L K G+ +LG V+ V
Sbjct: 176 GYIACEFAGIFNGLGRHVVQLHRGSQVLR-GFDDELREHLGDELKKSGIDLRLGVDVVAV 234
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
+++ + V + + ++ D V+ + GR P T GLGL+ V + LD G I V+
Sbjct: 235 ERQRGALSVQLTTG-----DAMEVDAVMAATGRLPNTWGLGLETVDVGLDQNGAIKVDEY 289
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPEVGW 388
+T+ PGIYA+GDV + L A EG + + G + ++ +P +++ P+
Sbjct: 290 SRTSSPGIYAVGDVTNRLNLTPVAIHEGHAFADTVFGGKALPTEHENVPFAVFSQPQAAS 349
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VG +E + ++ F A + + + VK++ + + D ++G HI+G
Sbjct: 350 VGLSEAQARDRYSNVEIYGSAFRPMRAALSGRDEKALVKLVVNGSNDRVVGAHIVGADAA 409
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAE 479
E+I +A + A D HPT AE
Sbjct: 410 EIIQGIAVAIKARATKADFDATLGVHPTLAE 440
>UniRef50_A7GZF3 Cluster: Probable pyridine nucleotide-disulfide
oxidoreductase YkgC; n=2; Campylobacter|Rep: Probable
pyridine nucleotide-disulfide oxidoreductase YkgC -
Campylobacter curvus 525.92
Length = 446
Score = 184 bits (449), Expect = 4e-45
Identities = 132/458 (28%), Positives = 224/458 (48%), Gaps = 27/458 (5%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTL-GGTCLNVGCIPSKALLHNSHLYHMA 91
D++VIG G G A KA LG KV +E+ P + GGTC+N+GCIP+K L+ +
Sbjct: 4 DIIVIGFGKAGKTLAAKAGALGKKVALIERSPQMYGGTCINIGCIPTKRLVTAAK----- 58
Query: 92 KHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTG-GIAMLFQKNKVNLVKGVGTIVAPNK 150
+ F +E T ++ K + L + ML ++++ GVG + N
Sbjct: 59 EAQFVNNNVEGDYYTLS----IQTKDKLITALRAKNLGMLKDNPNIDVIDGVGYFLDKNS 114
Query: 151 VEVHGEKGVET-VNTKNILIASGSEVTPFPGVTFDEKQII--TSTGALSLESVPKKMLVI 207
VE+ G + ++ I+I +GS+ P F+ K I TS+ L+L+++PK ++++
Sbjct: 115 VEILTADGSKCLIDGDTIVINTGSKEADAP---FEVKSDIAYTSSEILNLKTLPKHLVIV 171
Query: 208 GAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVL 267
G G IGLE S++ G+ VT + + D +VA ++++ L QG++ +
Sbjct: 172 GNGFIGLEFASMFAGFGSKVTIVGRGKFMKNE--DDDVANSVKEALVAQGIEILEDCNIS 229
Query: 268 GVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVN 327
+ G + ++GG + + D L+++GR+ T+GL LDKVG+ +D++G I VN
Sbjct: 230 SLMGRG------LNFSQGGMSKSIIADAFLLAMGRKAVTEGLNLDKVGVKIDEKGNIVVN 283
Query: 328 NKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI--KGMPVHFNYDAIPSVIYTSPE 385
QT P IYA+GDV G + + + D+ + + I KG N + ++T
Sbjct: 284 EFLQTDTPNIYAVGDVRGGELFTYTSLDDFRIVFDKIFGKGERSTKNRAIHANTLFTQTP 343
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGP 445
+ VG ++++ G+ K+ K A AK G +K + D + ILG
Sbjct: 344 LAKVGLSQKEATALGKDIKILKLSMSAVPGAKVVNHDIGMLKAIVDNKSGEILGAAFHCI 403
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
E+INE +A + A A HP+ +EAL +
Sbjct: 404 YAHEIINEVAIAMNFKANAGFFKNQIFTHPSISEALND 441
>UniRef50_A4IXR1 Cluster: Glutathione-disulfide reductase; n=11;
Francisella tularensis|Rep: Glutathione-disulfide
reductase - Francisella tularensis subsp. tularensis
(strain WY96-3418)
Length = 453
Score = 184 bits (449), Expect = 4e-45
Identities = 133/454 (29%), Positives = 214/454 (47%), Gaps = 16/454 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D++ +G G GG +A++AA+ G KV +EK LGGTC+N GC+P KA+ + ++L + K
Sbjct: 7 DVISLGGGSGGIASAVQAAKFGKKVAIIEKRE-LGGTCVNRGCVPKKAMWYGANLAEILK 65
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
HD G + F++ K+ E +A + + G L K + G NK
Sbjct: 66 HDVAGYGFDVEVKGFNWAKLKEKRATYIGNIHGFYDRLLDKWNITHFNNWGKF-KDNKTI 124
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQI-ITSTGALSLESVPKKMLVIGAGV 211
V + G E + +I I+ G+ P + ++ ITS LE PKK +++G G
Sbjct: 125 VL-DDGTE-LTADHIFISPGA--YPIVPKNIEGAELGITSDEFFELEETPKKAVIVGGGY 180
Query: 212 IGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKK 271
IG+E+ V G D T I + D ++ L + + + T + V+K
Sbjct: 181 IGVEIAGVLNAHGTD-TTIMVRRDKPLMEFDNCISDALVECMQMTDLNIMNHTNITKVEK 239
Query: 272 EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQ 331
GST+K+ + +K + D D ++ + GR P T LG++ I + D+G IP N +
Sbjct: 240 TGSTLKITTDT----DKVLEDVDTLIWATGRAPNTHNLGIENTDIRITDKGVIPANEWSE 295
Query: 332 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHF--NYDAIPSVIYTSPEVGWV 389
T V G+Y++GD P L A G + + N + IP+VI++ P +G V
Sbjct: 296 TNVAGVYSLGDASGVPQLTPVAIKTGRYLARRLFNGETNLKANLEYIPTVIFSHPAIGTV 355
Query: 390 GKTEEDLK-KEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
G TE++ + K G KV K F A A + +K++ + I+G H+IG
Sbjct: 356 GLTEKEARDKYGDENVKVYKSRFTALYCAISGHRMPTVMKLVVTGDNEKIVGCHMIGLNV 415
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
E++ +A GA D HPT +E L
Sbjct: 416 DEMLQGFAVAINMGATKRDFDDTIAIHPTSSEEL 449
>UniRef50_Q9NNW7 Cluster: Thioredoxin reductase 2, mitochondrial
precursor; n=63; Coelomata|Rep: Thioredoxin reductase 2,
mitochondrial precursor - Homo sapiens (Human)
Length = 524
Score = 184 bits (449), Expect = 4e-45
Identities = 153/492 (31%), Positives = 238/492 (48%), Gaps = 22/492 (4%)
Query: 19 VRIATRQYAT-THDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEK-DPT-------LGGT 69
VR A R A D DL+V+G G GG A +AAQLG KV V+ +P+ LGGT
Sbjct: 26 VRGAARGAAAGQRDYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGT 85
Query: 70 CLNVGCIPSKALLHNSHLYHMAKHDFKQRGIETGE-VTFDFKKMMEYKANAVKGLTGGIA 128
C+NVGCIP K L+H + L D G E + V D++KM E N VK L G
Sbjct: 86 CVNVGCIPKK-LMHQAALLGGLIQDAPNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHR 144
Query: 129 MLFQKNKVNLVKGVGTIVAPNKVEVHGEKGVETV-NTKNILIASGSEVTPFPGVTFDEKQ 187
+ Q KV + V + V + G E + + +I+IA+G + +
Sbjct: 145 VQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEY 204
Query: 188 IITSTGALSLESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAK 247
ITS L+ P K LV+GA + LE +G D T + + SI G D +++
Sbjct: 205 GITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIM--MRSIPLRGFDQQMSS 262
Query: 248 TLQKILSKQGMKFKLGTKVLGVKK-EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYT 306
+ + ++ G +F G V++ ++V E + G ++ D VL +IGR P T
Sbjct: 263 MVIEHMASHGTRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDT 322
Query: 307 KGLGLDKVGIALD-DRGRIPVNNKFQTTVPGIYAIGDVIHG-PMLAHKAEDEGIVCVEGI 364
+ L L+K G+ D +I V+++ T+VP IYAIGDV+ G P L A G + V+ +
Sbjct: 323 RSLNLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRL 382
Query: 365 KGMPVHF-NYDAIPSVIYTSPEVGWVGKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE- 421
G +YD +P+ ++T E G VG +EE+ + + G+ + G
Sbjct: 383 FGGSSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRD 442
Query: 422 -TEGFVKVLS-DKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAE 479
++ +VK++ + ++LG H +GP GE+ L + GA+ V R HPTC+E
Sbjct: 443 ASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSE 502
Query: 480 ALREANLAAYSG 491
+ + ++ SG
Sbjct: 503 EVVKLRISKRSG 514
>UniRef50_A6U5L4 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region precursor; n=2;
Sinorhizobium|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region precursor -
Sinorhizobium medicae WSM419
Length = 473
Score = 183 bits (446), Expect = 8e-45
Identities = 136/462 (29%), Positives = 224/462 (48%), Gaps = 19/462 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+ VIG G G A AA G+ VV VEK P +GG CLN GC+PSKAL+ S H +
Sbjct: 8 DICVIGGGAAGLTVAAGAAAFGVPVVLVEKGP-MGGDCLNHGCVPSKALIAASRHAHSIR 66
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAM-LFQKNKVNLVKGVGTIVAPNKV 151
+ GI D +++ + + G+ ++ F V ++K V N+
Sbjct: 67 VA-AEFGIAAAGPVIDQERLTARIQSVIVGIAPHDSVERFTSLGVEVIKDEACFV-DNRT 124
Query: 152 EVHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
G++ + + +IA+GS + P PG+ E +T+ SL+ +P+ ++VIG
Sbjct: 125 IAAGDR---LIRARRFVIATGSSPAIPPIPGLA--ETPFLTNETLFSLKRLPRHLVVIGG 179
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
G +GLE+ ++RLG +VT ++ ++ G D E+A + L +G+ T + V
Sbjct: 180 GPVGLEMAGAHRRLGVEVTVVDKTEALSGQ--DPELAAIVLDGLRAEGVHLHERTAIHAV 237
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
++ I++ E G ++ +L++ GR P LGLD GI D + RI V
Sbjct: 238 ERTERGIRLRCE--NGNGPFGIEGSDLLVAAGRAPVHASLGLDAAGIRHDPK-RIEVGPN 294
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIK-GMPVHFNYDAIPSVIYTSPEVGW 388
+T+ +YAIGD G + H+A + ++ I +P +P VI+T PE+
Sbjct: 295 LRTSNRRVYAIGDAAGG-LFTHQASYHARLVLQQILFRLPAREKPFIVPRVIFTEPELAH 353
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VG TEE ++ + + + AN R++T+G G +KV+ + V LG I G G G
Sbjct: 354 VGLTEERAREAAPGATILRLDYSANDRSRTDGLGRGLIKVVVGRRGRV-LGAAIAGSGAG 412
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYS 490
E+IN A + +PT +E ++A ++ YS
Sbjct: 413 EMINLWAFAVANRLTLKHFQTYVAPYPTLSEIGKQAAISYYS 454
>UniRef50_Q7V2B4 Cluster: Probable glutathione reductase; n=5;
Prochlorococcus marinus|Rep: Probable glutathione
reductase - Prochlorococcus marinus subsp. pastoris
(strain CCMP 1378 / MED4)
Length = 459
Score = 183 bits (445), Expect = 1e-44
Identities = 129/457 (28%), Positives = 228/457 (49%), Gaps = 25/457 (5%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLH--NSHLYHM 90
DL+V+G+G GG AA +AA G KV +E + +GGTC+ GC+P K +++ N+ +
Sbjct: 11 DLIVLGAGSGGLAAAKRAASYGAKVAIIEVNK-IGGTCVIRGCVPKKLMVYAANNRRNML 69
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
+ + G+ + E+TF+ +++ V L+ + +K V + +G+G + N
Sbjct: 70 SSEGY---GLISKEITFESNILLKNVREEVSRLSVLHSNSLKKLNVKVFEGLGRFLNQNT 126
Query: 151 VEVHGEKG---VETVNTKNILIASGSEVTPF--PGVTFDEKQIITSTGALSLESVPKKML 205
VEV K + V+ K+ILI+ G + PG F TS L+ PKK+L
Sbjct: 127 VEVVCPKTKNILRKVSAKSILISVGGKPKKLNIPGTDF----AWTSDDIFELKDFPKKLL 182
Query: 206 VIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTK 265
++G G I E S+++ LG +VT + ++ G D ++++ L+K ++ G+ K +
Sbjct: 183 IVGGGYIACEFASIFKNLGTEVTQLIRGENLLN-GFDKDLSECLEKSMTSLGINLKFKNQ 241
Query: 266 VLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIP 325
+ +KK ++ +E+ G+K L D +L++ GR P K L LD + + +D +
Sbjct: 242 LKSIKKINDGLESTLES---GSK--LLTDNILVATGREPSLKRLNLDTLNLKMDGI-YLE 295
Query: 326 VNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEG-IKGMPVHFNYDAIPSVIYTSP 384
VN +T++ I+AIGD++ P L A ++G V + + NY+ IP ++T P
Sbjct: 296 VNELNKTSISNIFAIGDIVKRPNLTPVAIEQGRVFADNYFAALKRKVNYENIPKAVFTIP 355
Query: 385 EVGWVGKTEEDLKKEGRAYKVGKFP--FLANSRAKTNGETEGFVKVLSDKTTDVILGTHI 442
E+ VG +EE + V F F S +++ +K++ +K D +LG H+
Sbjct: 356 EISTVGLSEEKANEIYSEVNVQVFKCNFTPMSNTFKKNKSKCMLKLVVNKKNDKVLGCHM 415
Query: 443 IGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAE 479
G E+I ++ G +D HPT +E
Sbjct: 416 FGEAASEIIQMVAVSLNTGITKKDFDTTMALHPTISE 452
>UniRef50_P00390 Cluster: Glutathione reductase, mitochondrial
precursor; n=203; cellular organisms|Rep: Glutathione
reductase, mitochondrial precursor - Homo sapiens
(Human)
Length = 522
Score = 183 bits (445), Expect = 1e-44
Identities = 138/460 (30%), Positives = 221/460 (48%), Gaps = 18/460 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D +VIG G GG +A +AA+LG + VE LGGTC+NVGC+P K ++ N+ ++
Sbjct: 66 DYLVIGGGSGGLASARRAAELGARAAVVESHK-LGGTCVNVGCVPKK-VMWNTAVHSEFM 123
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK-- 150
HD G + E F+++ + E + V L K+ + +++G + K
Sbjct: 124 HDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPT 183
Query: 151 VEVHGEKGVETVNTKNILIASGS-EVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
+EV G+K +ILIA+G TP ITS G LE +P + +++GA
Sbjct: 184 IEVSGKK----YTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGA 239
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
G I +E+ + LG+ T++ D ++ + L G++ ++V V
Sbjct: 240 GYIAVEMAGILSALGSK-TSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEV 298
Query: 270 KKEGSTIKVDVEAAKGGNKEVL----DCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIP 325
KK S ++V + A G V+ D D +L +IGR P TK L L+K+GI DD+G I
Sbjct: 299 KKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHII 358
Query: 326 VNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI--KGMPVHFNYDAIPSVIYTS 383
V+ T V GIYA+GDV +L A G + +Y+ IP+V+++
Sbjct: 359 VDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSH 418
Query: 384 PEVGWVGKTEED-LKKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTH 441
P +G VG TE++ + K G K F A T +T+ +K++ + ++G H
Sbjct: 419 PPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIH 478
Query: 442 IIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
+ G G E++ +A + GA D HPT +E L
Sbjct: 479 MQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEEL 518
>UniRef50_Q7NCV5 Cluster: Glr2871 protein; n=3; Cyanobacteria|Rep:
Glr2871 protein - Gloeobacter violaceus
Length = 450
Score = 182 bits (442), Expect = 3e-44
Identities = 140/453 (30%), Positives = 215/453 (47%), Gaps = 18/453 (3%)
Query: 32 ADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMA 91
AD++VIGSG GG A+ A+ G +VV E+ LGG+C+N GC PSKALL +H A
Sbjct: 4 ADVIVIGSGQGGVPLAVDQARSGRRVVLFERG-ALGGSCINYGCTPSKALLAAAHAAGRA 62
Query: 92 KHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
+ GI EVT DF ++ME GI V +V + + V
Sbjct: 63 RLA-APLGIHA-EVTVDFARVMERVRGIRASFRQGIEQRLADAGVQIVHAEASFAGSSTV 120
Query: 152 EVHGEKGVETVNTKNILIASGSEVT--PFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
V G GVE V ++I +G+ T PG+ ++T+ LE++P+ L++G
Sbjct: 121 -VGG--GVE-VQAPLVVINTGTGPTIPELPGLA--GLPLLTNLNIFDLETLPRCTLILGG 174
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
G IGLELG RLG++V + + + EV + L + L + G+ L ++V
Sbjct: 175 GYIGLELGQGLARLGSEVHIVHNHERLLNHE-EPEVGEVLAEALRRDGIHLHLQSEVSQA 233
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
+ + +E + E +L + GR P T LG GIALD +G + ++
Sbjct: 234 VYQDGICALTLEDGQILRGEA----ALLAAAGRTPNTAALGAPAAGIALDKQGYVAIDEH 289
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPS-VIYTSPEVGW 388
F+TT G+YAIGDV P H E ++ I G D + +YT P+VG
Sbjct: 290 FRTTAAGVYAIGDVARQPAFTH-VSWEDYRRLQAILGGEERTRSDRVLGYAVYTEPQVGR 348
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VG T + +G + P +RA G GF +++ D+ TD ILG ++G
Sbjct: 349 VGLTLDQALAKGHRARSVTLPMAHIARAIEWGHDLGFYRLVVDEDTDKILGATLVGYEAA 408
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
E+++ + + + + + + H HPT EAL
Sbjct: 409 EIVHVLLAHMQADSTWKVLEQSVHIHPTYCEAL 441
>UniRef50_A1SIG2 Cluster: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase; n=3;
Actinomycetales|Rep: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase - Nocardioides sp.
(strain BAA-499 / JS614)
Length = 484
Score = 182 bits (442), Expect = 3e-44
Identities = 139/459 (30%), Positives = 216/459 (47%), Gaps = 22/459 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DLV+IG G G V A AA+ G +V+ +E+D T GG CL GC+PSKALL + + A+
Sbjct: 13 DLVIIGGGTAGIVGAKTAARFGARVLLIERDRT-GGDCLWTGCVPSKALLAAADVAATAR 71
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTG-GIAMLFQKNKVNLVKGVGTIVAPNKV 151
+ G+E V+ DF ++ + A+ + + V + +G ++V
Sbjct: 72 SGHRL-GVEAYGVSVDFHAVLGHVRGAIDHIAPIDSPQALEAEGVTVWRGDAKFTGRDQV 130
Query: 152 EVHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
V + T L+A+G+ V PG+ + +TS L+ +P+ ++V+G
Sbjct: 131 AVGDRRATFT----QALLATGAAPAVPRIPGLA--QTPHLTSDSVWQLDRLPEDLVVLGG 184
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
G IG ELG + RLG+ VT +E + D + A + L G+ G V V
Sbjct: 185 GSIGCELGQAFARLGSRVTVVEGAPRLLPRE-DADAATAVTTGLRTDGVDVITGVAVTRV 243
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
+ G ++ E A G L +L+++GR P T G+GL+ G+ + D G + ++
Sbjct: 244 GQGGGRPRL--ELADG---RALAFSQLLVAVGRSPRTHGMGLELAGVEVTDHGFVRTDSH 298
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEG-IVCVEGIKGMPVHFNYDAIPSVIYTSPEVGW 388
+TT P I+A GD+ P H A G + + G+ + AIP V YT PEV
Sbjct: 299 LRTTNPRIWAAGDLTGHPQFTHTAGVHGSLAASNAVLGVRRKVDLSAIPRVTYTQPEVAA 358
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VG E R + RA T T GF ++ D+ ++ G ++GP G
Sbjct: 359 VGVGTESPPDGLRRL---TWQHTRVDRAVTELATGGFTRLTVDRRGRLV-GATVVGPRAG 414
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 487
E I E LA G D+A V HA+PT + L +A +A
Sbjct: 415 ESIGELTLAISQGLRTRDLAGVTHAYPTWNDGLWQAAIA 453
>UniRef50_Q6S4W1 Cluster: Dihydrolipoamide dehydrogenase precursor;
n=1; Toxoplasma gondii|Rep: Dihydrolipoamide
dehydrogenase precursor - Toxoplasma gondii
Length = 607
Score = 182 bits (442), Expect = 3e-44
Identities = 164/519 (31%), Positives = 237/519 (45%), Gaps = 72/519 (13%)
Query: 5 FLKLASPTFRSGSLVRI-ATRQYATTHDA--DLVVIGSGPGGYVAAIKAAQLGMKVVSVE 61
+ L+SP RS + R+ AT D D+ +IG G GG+ AA+ AA LG+K V
Sbjct: 112 YASLSSPQPRSEGVSRLFATSSSTNFSDEPFDVTIIGLGVGGHAAALHAAALGLKTAVVS 171
Query: 62 K-DPTLGGTCLNVGCIPSKALLHNSHLYHMA--KHDFKQRGIETGEVTFDFKKMMEYKAN 118
DP GGTC+N GC+PSKALL + M KH G++ ++
Sbjct: 172 GGDP--GGTCVNRGCVPSKALLAAARRVKMLRNKHHLSAMGLQV-------------RSG 216
Query: 119 AVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVEVHGEKGVETVNTKNILIASGS----- 173
V L LF V + G V + + TKN+++A GS
Sbjct: 217 LVSSLASHGIALFDARGV--MDGEPGRVVLERTAGSPASLPPFLRTKNVILAPGSLPFIP 274
Query: 174 -----EVTPFPGVTFDEKQ--IITSTGALSLESVPKKMLVIGAGVIGLELGSVYQRLGAD 226
E VTFD+ Q ++TS +SL +P ++ ++G+G IGLE V+ LG++
Sbjct: 275 AGTKEEQFSVRRVTFDDAQHQVMTSDTCVSLPWLPSEICIVGSGYIGLEFMDVFTSLGSE 334
Query: 227 VTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMK--FKLGTKVLG--VKKEG--STIKVDV 280
V +E + G+D EVAK +++L +Q + KL T L V+ G V+V
Sbjct: 335 VVMVEAGPRLLP-GVDKEVAKLAERLLLQQFKERPVKLYTNTLASQVRPLGPKGEAPVEV 393
Query: 281 EAAKGGNKEV---LDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVN---------- 327
+ KE + D LI+ GRRP T+GLGLD +G+ L G IPV+
Sbjct: 394 QLTDAQTKESKGKIYPDACLIATGRRPNTEGLGLDSLGVTLKRGGFIPVDACMRVLKHAP 453
Query: 328 --NKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPE 385
++ + G+Y +GD MLAH A + + VE I G P N IP+ +TSPE
Sbjct: 454 EGDEKPEVIRGVYCVGDANGQMMLAHAASAQAVAAVETIAGRPRTVNVKHIPAACFTSPE 513
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGP 445
+ ++GK NS+ T G +KVL K T ILG H+IG
Sbjct: 514 IAFIGKVNN---------------VTVNSKDSPLVSTPGILKVLYRKDTGKILGCHMIGI 558
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
+LI E A + +D+A H HPT +E + A
Sbjct: 559 HASDLIQECATAITNDISVKDLAFTVHTHPTLSEVVDAA 597
>UniRef50_P41921 Cluster: Glutathione reductase; n=39; cellular
organisms|Rep: Glutathione reductase - Saccharomyces
cerevisiae (Baker's yeast)
Length = 483
Score = 182 bits (442), Expect = 3e-44
Identities = 146/489 (29%), Positives = 233/489 (47%), Gaps = 24/489 (4%)
Query: 6 LKLASPTFRSGSLVRIATRQYATTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPT 65
L TFRS ++I T T H D +VIG G GG +A +AA G K + VE
Sbjct: 2 LSATKQTFRS---LQIRTMSTNTKH-YDYLVIGGGSGGVASARRAASYGAKTLLVEAK-A 56
Query: 66 LGGTCLNVGCIPSKALLHNSHLYHMAKHD-----FKQRGIETGEVTFDFKKMMEYKANAV 120
LGGTC+NVGC+P K + + S L H ++ ++ +TF++ + + + V
Sbjct: 57 LGGTCVNVGCVPKKVMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYV 116
Query: 121 KGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVEVHG-EKGVETVNTKNILIASGSEVTPFP 179
L G +K KV++V G VEV + E + +IL+A+G + FP
Sbjct: 117 HRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAI-FP 175
Query: 180 GVTFDEKQIITSTGALSLESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGV 239
+ S G LE PKK++V+GAG IG+EL V+ LG++ T +
Sbjct: 176 ENIPGFELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSE-THLVIRGETVLR 234
Query: 240 GIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLIS 299
D + T+ K+G+ +K++ V+K T K+ + +K + D D ++ +
Sbjct: 235 KFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIH--MNDSKSIDDVDELIWT 292
Query: 300 IGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIV 359
IGR+ + G+G + VGI L+ +I + T VP IY++GDV+ L A G
Sbjct: 293 IGRKSHL-GMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRK 351
Query: 360 CVEGIKGMPVHF-----NYDAIPSVIYTSPEVGWVGKTE-EDLKKEGRA-YKVGKFPFLA 412
+ G P F +Y+ +PSVI++ PE G +G +E E ++K G+ KV F A
Sbjct: 352 LSNRLFG-PEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTA 410
Query: 413 NSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCH 472
A + ++ K++ + ++G HI+G E++ +A + GA D
Sbjct: 411 MYYAMLSEKSPTRYKIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVA 470
Query: 473 AHPTCAEAL 481
HPT AE L
Sbjct: 471 IHPTSAEEL 479
>UniRef50_O05940 Cluster: Probable dihydrolipoyl dehydrogenase;
n=26; Bacteria|Rep: Probable dihydrolipoyl dehydrogenase
- Rhizobium etli
Length = 277
Score = 182 bits (442), Expect = 3e-44
Identities = 106/277 (38%), Positives = 156/277 (56%), Gaps = 5/277 (1%)
Query: 215 ELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKEGS 274
E S Y+ +G DVT +E + +I V D E+ +K L K+G+K KV V+K
Sbjct: 1 EFASFYRSMGVDVTVVEVMPTIMPVE-DAEITAIARKQLEKRGLKIFTSAKVTKVEKGAG 59
Query: 275 TIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQTTV 334
+I VE + G +++ D ++ ++G + + LGL+ +G+ L DR + + +T V
Sbjct: 60 SITAHVETSDGKVQQIT-ADRMISAVGVQGNIENLGLEALGV-LTDRRWLVADGYGKTNV 117
Query: 335 PGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMP-VH-FNYDAIPSVIYTSPEVGWVGKT 392
GIYAIGDV P++AHKAE EG+VCVE I G+P VH + +P Y +P+V VG T
Sbjct: 118 AGIYAIGDVAGPPIVAHKAEHEGVVCVEKIAGVPNVHPTDKGKVPGCTYCNPQVASVGLT 177
Query: 393 EEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELIN 452
E K+ G +VG+F F AN +A GE +G VKV+ DK T +LG H++G ELI
Sbjct: 178 EAKAKELGSDIRVGRFSFAANRKAIALGEDQGMVKVIFDKKTGELLGAHMVGAEVTELIQ 237
Query: 453 EAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAY 489
V+A E++ HPT +E ++EA L AY
Sbjct: 238 GFVVAMNLETTEEELMHTIFPHPTVSETMKEAVLDAY 274
>UniRef50_A0ZGC8 Cluster: Glutathione reductase; n=2;
Nostocaceae|Rep: Glutathione reductase - Nodularia
spumigena CCY 9414
Length = 447
Score = 181 bits (441), Expect = 3e-44
Identities = 130/457 (28%), Positives = 212/457 (46%), Gaps = 22/457 (4%)
Query: 29 THDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLY 88
T D DL VIG+G GG AA +AA G++V E++ T+GGTC+N GC+P K +++ + +
Sbjct: 2 TFDYDLFVIGTGTGGLAAAKQAASYGVRVAMAEQE-TIGGTCVNRGCVPKKLIVYAAD-F 59
Query: 89 HMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAP 148
G + FD+ M+ ++ + + + ++K V
Sbjct: 60 AQDNQMANSYGWSKCKRYFDWTLFMKSVHRHIEHINYSYCQQLRNAGIEIIKERAVFVDA 119
Query: 149 NKVEVHGEKGVETVNTKNILIASGSEVTP--FPGVTFDEKQIITSTGALSLESVPKKMLV 206
+ ++++G + V ILIA G + PG+ + ITS L +PK++ +
Sbjct: 120 HTLDLNGHQ----VTADKILIAVGGKPNKPQIPGIEY----AITSRQMFHLPYLPKRLAI 171
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
IG G IG E S+ LG VT +E + G D ++ +Q+ LSK+G++
Sbjct: 172 IGGGYIGAEFSSMMHALGCKVTLLE-RDEMMLSGFDDDIRSGVQQGLSKRGIRIFTNCTA 230
Query: 267 LGVKK--EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRI 324
+ EG +K + A E + D +L++ G T+ LGL+K + + +G I
Sbjct: 231 EEITHLDEGWLLKTTGDCA-----ETIAADTILVATGFSANTQNLGLEKAKVEVGKQGEI 285
Query: 325 PVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKG-MPVHFNYDAIPSVIYTS 383
VN F TT I+A+GD I+ L A+ EG+ + G P NYD +PS +++
Sbjct: 286 QVNEYFCTTQENIFAVGDCINRMQLTPVAKAEGMAFANTVFGNNPQTVNYDYVPSAVFSR 345
Query: 384 PEVGWVGKTEEDLK-KEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHI 442
PE VG TE + K G + K F E +K++ D + +LG H+
Sbjct: 346 PEGSGVGMTEAQAREKFGESVKCYCKRFQPLLYQLVEAEEPAMMKLVVDDNSQQVLGAHM 405
Query: 443 IGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAE 479
+G E+I +A G +D+ HPT AE
Sbjct: 406 LGENAAEIIQTLGVAIRQGITKQDLNETIGIHPTTAE 442
>UniRef50_A0Q826 Cluster: Dihydrolipoamide dehydrogenase; n=7;
Francisella tularensis|Rep: Dihydrolipoamide
dehydrogenase - Francisella tularensis subsp. novicida
(strain U112)
Length = 472
Score = 181 bits (440), Expect = 4e-44
Identities = 139/454 (30%), Positives = 221/454 (48%), Gaps = 25/454 (5%)
Query: 32 ADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMA 91
AD+ +IG G GG A A Q+G KVV E + +GG CLN GC+PSKA++ S + +A
Sbjct: 4 ADICIIGGGSGGLSVAAGAVQMGAKVVLCEGNK-MGGDCLNYGCVPSKAIIEASRV--IA 60
Query: 92 KHDFKQR---GIETGEVTFDFKKMMEY-KANAVKGLTGGIAMLFQKNKVNLVKGVGTIVA 147
K + Q I+ + D+KK+ E+ K K F+ VN+++ I+
Sbjct: 61 KVNKAQAFGINIDNNNIEIDYKKVQEHIKTTIAKIEPHDSVERFETLGVNVIQEYAQIID 120
Query: 148 PNKVEVHGEKGVETVNTKNILIASGSEVTPFPGVT-FDEKQIITSTGALSLESVPKKMLV 206
V+ G + + I+IA+GS P + E +T+ L+ P+ +++
Sbjct: 121 QYTVKA----GDNFIKARYIVIATGSRAA-IPKIKGLAEVNYLTNETIFDLKEKPEHLMI 175
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
+G G IG+EL Y LG+ VT E +I GV +D + K + K + G+ +
Sbjct: 176 VGGGPIGVELAQAYALLGSKVTIFEASDTILGV-LDNDCRKIILKEFDRLGISIITNVNI 234
Query: 267 LGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPV 326
+ ++ I + G+K + +LI+ GR P L LD VGI RG I V
Sbjct: 235 SEIAQDDQEINLYC-----GSK-LYQGSHLLIAAGRVPNLDKLDLDNVGIKYTSRG-IKV 287
Query: 327 NNKFQTTVPGIYAIGDVIHGPMLAHKA-EDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPE 385
++ +T IYAIGDV+ G H A G+V + +P+ +Y+++P +YTSPE
Sbjct: 288 DSCLRTNHKNIYAIGDVVGGYQFTHVAGYHAGVVIQNILFKLPIKVDYNSLPWSLYTSPE 347
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGP 445
V +VG+ + G K+ K + N RA + T G +KV +K ILG I+G
Sbjct: 348 VAYVGQNIAQAQTHGA--KILKLSYQNNDRAVASLVTNGLIKVAINK-KGYILGATIVGE 404
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAE 479
ELI + +A + +++A A+PT +E
Sbjct: 405 NASELIVQWTIAIKNKLKIKNMASHIVAYPTLSE 438
>UniRef50_Q9YBZ2 Cluster: Mercuric reductase; n=1; Aeropyrum
pernix|Rep: Mercuric reductase - Aeropyrum pernix
Length = 461
Score = 181 bits (440), Expect = 4e-44
Identities = 137/464 (29%), Positives = 209/464 (45%), Gaps = 27/464 (5%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D++VIG G G+ A + AA+ G V+ V + P LGGTC+N GC+PSK +L+N L K
Sbjct: 7 DIIVIGGGAAGFSAVVAAAEGGASVLLVSEGP-LGGTCVNFGCVPSKHVLYN--LSTARK 63
Query: 93 HDFKQRGIETGEVTFDFKKMME-YKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
K I E +K+ E + + L + V+ ++G AP V
Sbjct: 64 AGLK---ISLSEALEGARKVSETLRKEKYESLLDSLG-------VDYLRGRARFKAPGIV 113
Query: 152 EVHGEKGVETVNTKNILIASGSEV--TPFPGVTFDEKQ-IITSTGALSLESVPKKM---L 205
E G E K +IA G+ P PG+ EK I L E P M
Sbjct: 114 EADGR---EVRYRKAAIIAVGARTWRPPIPGLKEAEKAGRILDNERLFGEGPPPDMESVA 170
Query: 206 VIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTK 265
VIG G+E ++ R G ++ + + E ++++L G++ + +
Sbjct: 171 VIGGRAQGVEAAQIFARSGLKTVLLQRSGRLLPRD-EPEAGVYMKRVLEGDGVEVRTSAR 229
Query: 266 VLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIP 325
L V+ +++D E +G ++ + ++ GR+P GLGL+ VG+ + G I
Sbjct: 230 PLRVESVRGAVRIDYETPQGPAS--VEASYIYLATGRKPVLDGLGLENVGVRVSSDGFIV 287
Query: 326 VNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPE 385
VN K + PG+YA GD I G L A EG V G V +Y IP ++T PE
Sbjct: 288 VNEKLMAS-PGVYAAGDCIGGIQLEPVAAREGYVAALNALGGNVEMDYTVIPRAVFTDPE 346
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGP 445
VG TE +L ++ RA+ G GFVK++ D T + G H++ P
Sbjct: 347 FASVGLTERELARKLGVCACRTVDITQIPRARIMGYETGFVKMVVDPRTKKVAGVHMMAP 406
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAY 489
E I+EA + G +DV H P+ +E ++ A LA Y
Sbjct: 407 QAAEAIHEAAFILKAGMTVDDVIDTIHIFPSISEGIKYAALAFY 450
>UniRef50_A3U327 Cluster: Regulatory protein; n=4;
Alphaproteobacteria|Rep: Regulatory protein - Oceanicola
batsensis HTCC2597
Length = 449
Score = 180 bits (439), Expect = 6e-44
Identities = 138/456 (30%), Positives = 220/456 (48%), Gaps = 21/456 (4%)
Query: 29 THDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLY 88
T DL+VIG G GG A AA G V S++ +P GGTC GC P K L+ +
Sbjct: 2 TKSYDLIVIGGGTGGNGVARMAANAGWSVASIDSEPH-GGTCALRGCDPKKMLIAVTEGV 60
Query: 89 HMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAP 148
A++ K +G+E + + ++ M+ +K + + I +K ++++ G P
Sbjct: 61 EWAEN-MKGKGLEA-QPSVNWSDMIAFKRSFTDAMPPRIEAGLEKAGIDVLHGEVRFTGP 118
Query: 149 NKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
+ +E++GE T+ K+ IA+G+ P E+ + TST L L P ++ +G
Sbjct: 119 DAIELNGE----TLRAKHFHIATGAR--PMTLNIPGEEYLATSTDFLELPERPDRIAFVG 172
Query: 209 AGVIGLELGSVYQRLGA-DVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVL 267
G I +E V +R GA +VT +E + G D ++ L + ++ G+ + KV
Sbjct: 173 GGFIAMEFAHVAKRAGAREVTVLEMMDRPLG-NFDPDLVAMLVEATAELGVDLRTKAKVA 231
Query: 268 GVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVN 327
++K+G + V VE G E + CD+V+ GR P GL L+ G+ RG I V+
Sbjct: 232 KIEKQGDEVVVTVERHDG--TETITCDLVVHGTGRVPNIDGLNLEAAGVEYSRRG-IKVS 288
Query: 328 NKFQTTVPGIYAIGDVIH-GPMLAHKAEDEGIVCVEGIKGMPV--HFNYDAIPSVIYTSP 384
+ + T P I+A GD G L + EG + + I G Y IPSV++T P
Sbjct: 289 DAMRATNPAIFAAGDCADSGLNLTPVSAAEGRIAGKNILGGKDAREIKYPPIPSVVFTLP 348
Query: 385 EVGWVGKTEEDLKKEGRAYKVGKFPFLAN--SRAKTNGETEGFVKVLSDKTTDVILGTHI 442
V VG +E +++G + V F S + + GF KVL ++ + ILG H+
Sbjct: 349 MVATVGLSEAAAREQGLKFDV-HFEKTEGWYSSLRVGAKHTGF-KVLVERGSGQILGAHL 406
Query: 443 IGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCA 478
IGPG E IN +A G A + + A+P+ A
Sbjct: 407 IGPGAEEQINLFAMAMGAGQTANQIKAMIFAYPSYA 442
>UniRef50_Q4J868 Cluster: Mercuric reductase; n=10; Archaea|Rep:
Mercuric reductase - Sulfolobus acidocaldarius
Length = 454
Score = 180 bits (438), Expect = 8e-44
Identities = 137/458 (29%), Positives = 221/458 (48%), Gaps = 22/458 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL +IG G G+ A I+A +LG+K V + +GGTC+NVGC+PSK LL Y A
Sbjct: 3 DLAIIGYGAAGFSALIRANELGIKPVIIGYGE-IGGTCVNVGCVPSKRLLSIGETYKYAS 61
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGL-TGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
Q+ T +F+K E K+ V L + ++KG ++PN +
Sbjct: 62 IALNQK------TTPNFEKSFEDKSEIVSSLRKEKYEDVLNSYDAKVIKGRAHFISPNAI 115
Query: 152 EVHGEKGVETVNTKNILIASGSEVTPFPGVT-FDEKQIITSTGALSLESVPKKMLVIGAG 210
+V+G E V K +IA+GS + P + E T+ ALS + +IG
Sbjct: 116 KVNG----EIVEAKKFIIATGSSPS-IPDIKGLREAGYWTNVEALSPTRRISSLAIIGGR 170
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
+ LE +Y+RLG D ++ I + E++ +++ L + + T+V VK
Sbjct: 171 ALALEFSQMYKRLGVDTVILQRSNRI-LPNWEPEISLSVKSYLENM-EEIPVFTQV-KVK 227
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
+ + V G EV D +L++ GRRP L L+ G++L+++G + V+ +
Sbjct: 228 EVETKNDQKVIITDMGEVEV---DEILVATGRRP-NVDLNLNVAGVSLNEKGGVKVDEEL 283
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVE-GIKGMPVHFNYDAIPSVIYTSPEVGWV 389
+TT P I+A GDVI ML A EG + V+ I + +IP V++ P V V
Sbjct: 284 RTTNPNIFAAGDVIGEQMLESVAGKEGFIAVDNAILNSHKKIDKLSIPQVVFIDPNVSRV 343
Query: 390 GKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGE 449
G T+ + + G + +A+ E+ G +K++ ++ ILG I G E
Sbjct: 344 GLTQVEAESSGYTVDYRVVNMESVPKARILRESHGLIKMVVNREDMRILGAEIFGKNSAE 403
Query: 450 LINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 487
+INEA LA ++ A D+ H PT +E+L+ A +A
Sbjct: 404 IINEAALAIKFRATIYDIIDTIHVFPTMSESLKIAAIA 441
>UniRef50_Q6A6B6 Cluster: Pyridine nucleotide-disulphide
oxidoreductase; n=3; Bacteria|Rep: Pyridine
nucleotide-disulphide oxidoreductase - Propionibacterium
acnes
Length = 468
Score = 180 bits (437), Expect = 1e-43
Identities = 128/456 (28%), Positives = 216/456 (47%), Gaps = 25/456 (5%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTL-GGTCLNVGCIPSKALLHNSHLYHMA 91
D++VIG G G A + A G KV VE+ + GG+C+N+ C+P+K L+ ++ +
Sbjct: 24 DVLVIGWGKAGKTIAGRLAAEGRKVALVERSAQMYGGSCINIACVPTKDLIDSA-----S 78
Query: 92 KHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
K D + D ++ A T AML + KV L+ GV + P+ V
Sbjct: 79 KRDGRDPASYFTSAVADRDTLI-----ATLNRTNH-AML--EGKVLLLDGVASFTGPHTV 130
Query: 152 EVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGV 211
+V TV + I++ +GS P D ++ ST ++ +P +++++G G
Sbjct: 131 KVVAGDDEITVRAETIIVNTGSHPANLPVPGADGPRVHDSTTIQHVDPLPSQLVIVGGGF 190
Query: 212 IGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKK 271
IGLE ++ R G+ VT +E + +D ++A+ ++ +L +G+ G +V +
Sbjct: 191 IGLEFAQMFARFGSQVTLLEAGETFVPA-LDTDIAERVRNMLEGEGVTVVTGAQVTSCDE 249
Query: 272 EGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQ 331
G + V + + D VL++ GRRP T+ L L G+A D+RG I V+++ +
Sbjct: 250 TGDHVDVVTD------DQTFAADAVLVAAGRRPATEDLDLTAAGVATDERGYITVDDQLR 303
Query: 332 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMP-VHFNYDAIPSVIYTSPEVGWVG 390
T + G+YA+GDV GP + + D+ V + + P + A+P+ + P + VG
Sbjct: 304 TNIDGVYAVGDVNGGPQFTYISLDDNRVLWDTLHDGPRRRDDRVAVPATTFLDPPLSQVG 363
Query: 391 KTEEDLKKEGRAYKVGK---FPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
T ++ GR+ V A R K G+TEG ++VL D +LG +
Sbjct: 364 MTMRQARESGRSVLVATKDVATIAAMPRPKIVGQTEGVIRVLVDADDHTVLGATLWCIDS 423
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
EL+N LA G E + HP+ EA E
Sbjct: 424 QELVNFVSLAMRLGVRYETLRDGIWTHPSSTEAFNE 459
>UniRef50_Q9RKH2 Cluster: Putative oxidoreductase; n=1; Streptomyces
coelicolor|Rep: Putative oxidoreductase - Streptomyces
coelicolor
Length = 505
Score = 179 bits (435), Expect = 2e-43
Identities = 141/465 (30%), Positives = 210/465 (45%), Gaps = 25/465 (5%)
Query: 20 RIATRQYATTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSK 79
R R++ DLVVIG G G AA A +LG + + VE+D LGG CL GC+PSK
Sbjct: 28 RRTDREFRAMKRYDLVVIGGGSAGLTAARTAGRLGARTLLVERD-RLGGDCLWTGCVPSK 86
Query: 80 ALLHNSHLYHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTG-GIAMLFQKNKVNL 138
ALLH + A+ G+ D + A+ + A V++
Sbjct: 87 ALLHVAADVQAARRATAY-GLPPVTGPADLTAALAEVKRAIGAIEPHDSAEALAPYGVDV 145
Query: 139 VKGVGTIVAPNKVEVHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALS 196
G + P + G V+ + LIA+GS + P PG+ E +TS
Sbjct: 146 THGAASFTGPGTLTA----GEREVSFRYALIATGSSPALVPIPGLV--ESGPLTSDTVWE 199
Query: 197 LESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQ 256
L +P ++V+G G IG ELG + RLG+ VT +E +D V + ++ + Q
Sbjct: 200 LSELPHLLVVLGGGPIGCELGQAFARLGSQVTLVE--------AMDRLVPR--EEPRASQ 249
Query: 257 GMKFKLGTKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGI 316
++ +L ++ + V + +VD +A G L D +L GRR +T GLGL+ G+
Sbjct: 250 VLRERLQSEGVTVLTDYRAERVDADAVHGPGGP-LPYDALLAVTGRRSHTHGLGLEAAGV 308
Query: 317 ALDDRGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDE-GIVCVEGIKGMPVHFNYDA 375
L D G I + + +TT IYA GDV H + G V+ + G+ +Y A
Sbjct: 309 ELTDAGHIRTDGRLRTTNHRIYAAGDVTGRSAFTHLGGTQGGAAAVDALLGVRRPIDYRA 368
Query: 376 IPSVIYTSPEVGWVGKT-EEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTT 434
P V YT PE+ VG T +E K G +V RA +G TEGF ++
Sbjct: 369 APRVTYTDPEIAGVGLTLDEAHAKYGDRARVHTLENDRVDRAVADGRTEGFTTLVLGPRG 428
Query: 435 DVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAE 479
++ G ++ P GE + A G D AR H +PT A+
Sbjct: 429 KIV-GATVVSPRAGETVAHLAAAVRLGWTPSDYARTVHPYPTYAD 472
>UniRef50_Q2IA26 Cluster: Chloroplast glutathione reductase; n=1;
Pavlova lutheri|Rep: Chloroplast glutathione reductase -
Pavlova lutherii (Monochrysis lutheri)
Length = 446
Score = 179 bits (435), Expect = 2e-43
Identities = 143/406 (35%), Positives = 203/406 (50%), Gaps = 23/406 (5%)
Query: 14 RSGSLVRIATRQYATTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNV 73
RS S +R Q A H + +VIG+G GG +A +AAQ G KV VE+ LGGTC+NV
Sbjct: 31 RSASTLRGGGVQLADGH-YEYLVIGAGSGGIASARRAAQYGAKVAVVER-ARLGGTCVNV 88
Query: 74 GCIPSKALLHNSHLYHMAKHDFKQRGIETGEVT-FDFKKMMEYKANAVKGLTGGIAMLFQ 132
GC+P K L + ++ A H K G++ G FD++ + + L G Q
Sbjct: 89 GCVPKK-LFFTAGVHMEAMHTAKGYGLDVGTPPKFDWEGFKARRDAYIANLNGIYLRNMQ 147
Query: 133 KNKVNLVKGVGTIVAPNKVEVHGEKGVETVNTKNILIASGSEVT--PFPGVTFDEKQIIT 190
+KV V+G + V VEV G G T + NILIA+G + P PG + T
Sbjct: 148 NSKVEFVEGYASFVDAKTVEVTGH-GRFTAD--NILIAAGGKPIHPPVPGGELAK----T 200
Query: 191 STGALSLESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQ 250
S LE P+ +V+GAG + +EL + LG D T + + G D V L
Sbjct: 201 SDDFFDLEHQPRTAVVVGAGYVAVELAFIMHELGTDTTLVCRGEKVLRHGFDPMVQDVLN 260
Query: 251 KILSKQGMKFKLGTKVLGVK-KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGL 309
+ +QG+ + T++ +K E T +V K G+ + DVVL + GRRP G+
Sbjct: 261 SEMERQGISMRRKTELGSIKLAEDGTYEVTF---KDGSM-LTGIDVVLYAAGRRPILTGM 316
Query: 310 GLDKVGIALDDRGRIPVNNKFQTTVPGIYAIGDV-IHGPMLAHKAEDEGIVCVEGIKG-- 366
L+ G+ L DRG I V+ +T VPGI+A+GDV G LA A G + + G
Sbjct: 317 CLENAGVELSDRGFITVDEYERTNVPGIHALGDVTTTGYELAPVAIAAGRRLSDRLYGGE 376
Query: 367 MPVHFNYDAIPSVIYTSPEVGWVGKTEED-LKKEGRA-YKVGKFPF 410
YD IP+V+++ P +G VG TE D L++ G A KV K F
Sbjct: 377 PRARLEYDRIPTVVFSHPPIGTVGLTEPDALEQYGEASVKVYKSSF 422
>UniRef50_A6WBN3 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=2;
Actinomycetales|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Kineococcus
radiotolerans SRS30216
Length = 502
Score = 178 bits (434), Expect = 2e-43
Identities = 127/457 (27%), Positives = 216/457 (47%), Gaps = 14/457 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D+VV+G GP G AA++AA+LG + +E T GGTC+N GC+P++ L + L +
Sbjct: 45 DVVVVGGGPAGVSAAVRAAELGARTALLEGSRT-GGTCVNTGCVPTRVLAKTARLVREVR 103
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIA--MLFQKNKVNLV-KGVGTIVAPN 149
+ GI + + D+ + V+ + A V+LV +G V P+
Sbjct: 104 -TAAEYGIAVPQQSVDWPATVARVRATVERVQAAKADPQRLADLGVDLVLEGRARFVDPH 162
Query: 150 KVEVHGEKGVETVNTKNILIASG-SEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
+E+ G +L G S P PG E T L L S+P+++ V+G
Sbjct: 163 VLEL-AATGRRVRGESVVLCVGGRSRRLPLPGA---ELATYPET-VLELPSLPRRLAVVG 217
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
AG G +L +V++ LG++V ++ + D +V+ +++ +QG++ G +
Sbjct: 218 AGNTGSQLVTVFRALGSEVQLLDLAPRVLPTA-DADVSHAVRRAFEEQGVRVATGIDAVH 276
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
+ + +D+ ++GG + D V++S+G GLGL+ GI + R + V+
Sbjct: 277 SLRRRADGAIDLAWSQGGTRSEEAFDAVVMSVGWPAALDGLGLEAAGIEVT-RSAVAVDE 335
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEG-IVCVEGIKGMPVHFNYDAIPSVIYTSPEVG 387
+T+VP ++A GD ML A E + G + +PS +T P+
Sbjct: 336 HLRTSVPHVFAAGDANGQAMLVQAAHAEAEAAATNAVLGATRRTPHLLLPSGGFTDPDYA 395
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG TE++ + V PF A RA + T GF+K+++D+ DV+LG H +G
Sbjct: 396 GVGLTEDEARARDPHCLVVTVPFTAMERAIIDDRTRGFLKLIADRRRDVLLGAHAVGEEA 455
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
E++ A G +ARV A+PT + + EA
Sbjct: 456 VEIVQAVTTAMAAGVDVATLARVEFAYPTYSAVIGEA 492
>UniRef50_Q5NN75 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex; n=8; Sphingomonadales|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex -
Zymomonas mobilis
Length = 448
Score = 178 bits (433), Expect = 3e-43
Identities = 130/455 (28%), Positives = 209/455 (45%), Gaps = 13/455 (2%)
Query: 28 TTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHL 87
T +D DL VIG+G GG A+ AA G V ++ ++ +GGTC+ GC+P K L + +
Sbjct: 2 TDYDFDLFVIGAGSGGVRASRIAASHGASV-AIAEEYRIGGTCVIRGCVPKKMLYYAADF 60
Query: 88 YHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVA 147
K ++ G E FD+ + + + V L G N + K I +
Sbjct: 61 AADLKKA-QRFGWTLPEKKFDWATLRDVVLSDVTRLEGLYTQTLDNNHITHYKEHAVIDS 119
Query: 148 PNKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVI 207
N++ + K + + IL+A G+E P + +TS L S+PK+ LV+
Sbjct: 120 ANQIRLASGK---KITARYILVAVGAE--PAKLDILGAEYAVTSNEMFLLPSLPKRALVV 174
Query: 208 GAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVL 267
G G I E + G + T I G D E+A L +I G+ ++ +
Sbjct: 175 GGGYIANEFAGILNSFGVETTIATHGDRILR-GYDEEIAARLVEIGQGHGIDYRFNADIA 233
Query: 268 GVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVN 327
+ K+ S ++ G ++ D+VL +IGR ++ LGLDK + +DRG I V+
Sbjct: 234 RIDKDSSG-RLTTHFKDGSQ---IESDLVLFAIGRVAKSRDLGLDKADVKTNDRGAILVD 289
Query: 328 NKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKG-MPVHFNYDAIPSVIYTSPEV 386
+ +T+ P IYA+GDV L A EG + + G +YD IP+ +++ P +
Sbjct: 290 EENRTSCPSIYAVGDVTDRVQLTPVAIREGQAFADRVFGHKAASVDYDTIPTAVFSHPPL 349
Query: 387 GWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPG 446
G TEE+ KK + K+ K F A + K++ D +D +LG H+IG
Sbjct: 350 ASAGLTEEEAKKRYKNIKIYKSNFRPMRNALIDSPDRALYKMVVDGDSDKVLGLHLIGQD 409
Query: 447 GGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
E+I A +A + G + HP+ AE L
Sbjct: 410 SPEIIQLAAVAIKAGLTKQAFNDTVALHPSSAEEL 444
>UniRef50_A0LCP2 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=1; Magnetococcus
sp. MC-1|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Magnetococcus sp.
(strain MC-1)
Length = 466
Score = 178 bits (433), Expect = 3e-43
Identities = 138/458 (30%), Positives = 216/458 (47%), Gaps = 23/458 (5%)
Query: 29 THDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLY 88
T D+++IG+G G A Q V V++ P LG TC VGC+PSKAL+ + Y
Sbjct: 2 TRQVDVIIIGAGTAGLYAMSVVKQQTSHFVVVDQGP-LGTTCARVGCMPSKALIQTADDY 60
Query: 89 HMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNK-VNLVKGVGTIVA 147
H A+ ++ G+ + T + + L+ I+ L++G VA
Sbjct: 61 HNAQRMVRE-GLLSETPTMQPQAGPAFALKISHMLSSKISERVSGGLGEKLIQGRARFVA 119
Query: 148 PNKVEVHGEKGVETVNTKNILIASGSE-VTPFPGVTFDEKQIITSTGALSLESVPKKMLV 206
+ +EV+G+ T+ K I++A+GSE V P P F + I+ S G L+ +PK + V
Sbjct: 120 KDTIEVNGQ----TLQAKAIILATGSEPVIPAPWRAFGAR-ILDSEGVFQLQEMPKSLAV 174
Query: 207 IGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKV 266
+G G IGLELG LG VT +E + + D E+ L + G +F L
Sbjct: 175 LGLGAIGLELGQALSTLGVAVTGVEMAQHVANLQ-DPEIR---AMALEQFGKQFPLHLGH 230
Query: 267 LGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPV 326
EG ++ V+A G ++ + VL+S+GRRP +GL +VGIALD RG +P+
Sbjct: 231 AASLSEGENGQIRVQA---GPLDI-QVEKVLVSLGRRPRVADMGLAEVGIALDARG-VPL 285
Query: 327 NNKFQTTVPG--IYAIGDVIHGPMLAHKAEDEG-IVCVEGIKGMPVHFNYDAIPSVIYTS 383
+ T V G I+ GD + ++ H+A +EG + G++ P F +I+T
Sbjct: 286 FDPTTTKVEGAPIFIAGDCTNDRVIFHEAAEEGKMAGFNGLREHPQRFQRKTPLGIIFTD 345
Query: 384 PEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHII 443
P + G E G ++ SRAK G V++ +D T +LG +I
Sbjct: 346 PNIATFGMGYEAALAAGA--QMASATIHTESRAKVMGVEAAMVRLYADPATGRLLGGALI 403
Query: 444 GPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
P G + + V A + G +A + + HP EAL
Sbjct: 404 SPRGEHMAHTLVWAVQGGLTVHQMASMPYYHPNLEEAL 441
>UniRef50_P08332 Cluster: Mercuric reductase (EC 1.16.1.1) (Hg(II)
reductase); n=313; root|Rep: Mercuric reductase (EC
1.16.1.1) (Hg(II) reductase) - Shigella flexneri
Length = 564
Score = 178 bits (433), Expect = 3e-43
Identities = 129/456 (28%), Positives = 208/456 (45%), Gaps = 12/456 (2%)
Query: 34 LVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAKH 93
+ VIGSG AA+KA + G +V +E+ T+GGTC+NVGC+PSK ++ +H+ H+ +
Sbjct: 100 IAVIGSGGAAMAAALKAVEQGARVTLIERG-TIGGTCVNVGCVPSKIMIRAAHIAHLRRE 158
Query: 94 DFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGI--AMLFQKNKVNLVKGVGTIVAPNKV 151
GI T ++ + V L +L + ++ G +
Sbjct: 159 SPFDGGIAATTPTIQRTALLAQQQARVDELRHAKYEGILEGNPAITVLHGSARFKDNRNL 218
Query: 152 EVH-GEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
V + G V LIA+G+ V P PG+ + TST AL E++PK++ VIG
Sbjct: 219 IVQLNDGGERVVAFDRCLIATGASPAVPPIPGLK--DTPYWTSTEALVSETIPKRLAVIG 276
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
+ V+ LEL + RLGA VT + T D + + + +G++ + T+
Sbjct: 277 SSVVALELAQAFARLGAKVTILARSTLF--FREDPAIGEAVTAAFRMEGIEVREHTQASQ 334
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
V D E L D +L++ GR P T+ L LD G+ L +G I ++
Sbjct: 335 VAYINGVR--DGEFVLTTAHGELRADKLLVATGRAPNTRKLALDATGVTLTPQGAIVIDP 392
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGW 388
+T+V IYA GD P + A G + G N A+P+V++T P+V
Sbjct: 393 GMRTSVEHIYAAGDCTDQPQFVYVAAAAGTRAAINMTGGDAALNLTAMPAVVFTDPQVAT 452
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VG +E + +G RA N +T GF+K++ ++ + ++G + P G
Sbjct: 453 VGYSEAEAHHDGIKTDSRTLTLDNVPRALANFDTRGFIKLVVEEGSGRLIGVQAVAPEAG 512
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
ELI A LA +++A + T E L+ A
Sbjct: 513 ELIQTAALAIRNRMTVQELADQLFPYLTMVEGLKLA 548
>UniRef50_Q041G8 Cluster: Acetoin/pyruvate dehydrogenase complex, E3
component, dihydrolipoamide dehydrogenase; n=3;
Lactobacillus|Rep: Acetoin/pyruvate dehydrogenase
complex, E3 component, dihydrolipoamide dehydrogenase -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 443
Score = 177 bits (430), Expect = 7e-43
Identities = 126/455 (27%), Positives = 219/455 (48%), Gaps = 27/455 (5%)
Query: 35 VVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTL-GGTCLNVGCIPSKALLHNSHLYHMAKH 93
++IG G GG A AQ +V+ +EK + GGTC+N+ C+PSK L+ +
Sbjct: 7 IIIGFGKGGKTLAKFLAQKSEEVLVIEKSNKMYGGTCINIACLPSKRLIIEA-------- 58
Query: 94 DFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVEV 153
G+ + +M N ML + V ++ G +A +++EV
Sbjct: 59 ---ANGVSYVDAVSGKNEMTAQLRNK------NYHMLADEQTVTVLDGEAHFIADHEIEV 109
Query: 154 HGEKGV-ETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
G E + I I +G+ + P PG+ + K I+ ST A+ + +P+ + +IGAG
Sbjct: 110 VLTNGKKEQFKGERIFINTGAVPVMLPIPGLK-ESKYILDSTQAMDEKKMPENLTIIGAG 168
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
IGLE S++ + G+ VT ++ D ++++ ++K L G+ F+LG + +
Sbjct: 169 YIGLEFASMFAKYGSKVTVLDHSREFLSRE-DDDISQLVKKDLEDAGVHFELGADIEEII 227
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
E + KV + G ++ + + +L + GR+P + LGL+ I + DRG I V++
Sbjct: 228 DEENEAKVRYQI--NGQEKEISANRILAATGRKPNIENLGLENTSIEITDRGAIKVDDFL 285
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYD--AIPSVIYTSPEVGW 388
+TTV ++AIGDV G + + D+ + + + G D +P ++ SP +
Sbjct: 286 RTTVDNVWAIGDVKGGLQFTYISLDDFRIIKDQLFGTGARMISDRKVVPYSVFISPALSQ 345
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VG E+ + + + YK+ K P A +AK ++ G K L D T+ ILG + G
Sbjct: 346 VGLNEKQARNQNKEYKLFKLPVAAIPKAKVAKDSRGLFKALVDPETEEILGATLYGIESY 405
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
ELIN LA + + + + HPT +EA +
Sbjct: 406 ELINLISLAMKAHLSYTVLRDQIYTHPTMSEAFND 440
>UniRef50_A5FRC9 Cluster: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase precursor; n=3;
Dehalococcoides|Rep: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase precursor -
Dehalococcoides sp. BAV1
Length = 489
Score = 177 bits (430), Expect = 7e-43
Identities = 126/454 (27%), Positives = 218/454 (48%), Gaps = 15/454 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DLVVIGSG G+ + + A LG KV VEK LGG C C+PSK LL K
Sbjct: 6 DLVVIGSGLAGFTSTVFANGLGKKVAMVEKGK-LGGACTWNACVPSKTLLQIGRRVGQIK 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAM-LFQKNKVNLVKGVGTIVAPNKV 151
+ Q G++ V + +M Y + ++ ++G +K +N++KG + +
Sbjct: 65 K-YNQNGLKLVSVNLQTENIMPYLHSVLEDISGVDDFDNLEKTGINILKGEAVFTDRHHI 123
Query: 152 EVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGV 211
++G+ V+ K+ +IA+GS P + T+ ++S+P M+V+G G
Sbjct: 124 SLNGQ----VVSAKHFIIATGSSPAIPPVEGLADIPYYTNETVFDIKSIPSSMIVLGGGP 179
Query: 212 IGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKIL-SKQGMKFKLGTKVLGV- 269
G+ELG + LG V IE I D E++ L L +++ ++ + TK +
Sbjct: 180 AGIELGLAFAWLGCKVDIIEMAERILPKD-DTELSGLLLDYLNAEENLQIHVSTKAIRFQ 238
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
+++ +K++++ +G E+ + VL+++GRR GL L+K G+ RG I VN+K
Sbjct: 239 EQDNGQLKLEMQTREGKINEI-TAETVLVAVGRRANVAGLALEKAGVKYTARG-ISVNSK 296
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCV-EGIKGMPVHFNYDAIPSVIYTSPEVGW 388
QT+ I+A GDV L AE + I+ YD + V Y+ P++
Sbjct: 297 LQTSSLNIFAAGDVAGPIQLGMMAEKQAILAASNACLPFKQSIRYDDVAWVTYSEPQMAH 356
Query: 389 VGKTEEDL-KKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
+G TE++ +K G ++ ++P RA + + G K + DK D ++G H++
Sbjct: 357 IGLTEDEARRKYGNNIRIIRYPLTKVRRAVMDHDIRGMCKFVLDK-HDRLIGAHLLCSQA 415
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
LI+E + + + + H +PT E +
Sbjct: 416 ENLIHELQIVKCLHKPLSRLHTIPHIYPTYEEGI 449
>UniRef50_A1B892 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=3;
Alphaproteobacteria|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Paracoccus
denitrificans (strain Pd 1222)
Length = 466
Score = 177 bits (430), Expect = 7e-43
Identities = 141/459 (30%), Positives = 211/459 (45%), Gaps = 26/459 (5%)
Query: 31 DADLVVIGSGPGGYVAA-IKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYH 89
D DL VIG G GG AA I A++ G +V + ++ +GGTC+ GC+P K ++ S
Sbjct: 4 DYDLFVIGGGSGGVRAARIAASEYGARV-GLAEESRMGGTCVIRGCVPKKLMIFASQAGA 62
Query: 90 MAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPN 149
A GE FD+ + + L G + VN G V
Sbjct: 63 AAAESRGYGWQGAGEGRFDWAEFHGKLGRELDRLEGA----YTSGLVN----AGVEVHMQ 114
Query: 150 KVEVHGEKGVETVN-----TKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKM 204
+ +H VE + K+ILIA G P + E +I S +LE +P ++
Sbjct: 115 RARLHDAHTVELADGQRLTAKHILIAIGGRPQR-PDIPGKELGLI-SDDLFTLEKLPGRV 172
Query: 205 LVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGT 264
LV+G G I E ++ Q LG+ T + + G DGE+ + + + L G+ +LGT
Sbjct: 173 LVVGGGFIACEFATILQGLGS-ATVLAYRGDAVLRGFDGEMRRHVTEQLRAIGVDVRLGT 231
Query: 265 KVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRI 324
+ +EG+ ++V E + E+ D V+ + GR PYTKGLGL+ G+ L +G I
Sbjct: 232 NPARLDREGAGVRVTFE---DDSSEIFDA--VMFATGRVPYTKGLGLEDAGVKLGRKGEI 286
Query: 325 PVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKG-MPVHFNYDAIPSVIYTS 383
V+ Q++VP I+A+GDV L A EG + + G P ++ + S +YT
Sbjct: 287 VVDEWSQSSVPSIFAVGDVTDRVNLTPVAIREGHSFADTVFGARPRKVDHRLVASAVYTR 346
Query: 384 P-EVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHI 442
P E+ +G TEE+ G A V F + +K++ D TD +LG HI
Sbjct: 347 PHELATIGLTEEEADACGPA-DVYVASFRPMRSLFAGSDARAVMKLIVDAQTDKVLGCHI 405
Query: 443 IGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
GP GE+I + GA D HPT AE L
Sbjct: 406 FGPEAGEMIQMIAVPMGMGATKADFDAAIAVHPTLAEEL 444
>UniRef50_P48638 Cluster: Glutathione reductase; n=57; Bacteria|Rep:
Glutathione reductase - Anabaena sp. (strain PCC 7120)
Length = 459
Score = 177 bits (430), Expect = 7e-43
Identities = 132/465 (28%), Positives = 222/465 (47%), Gaps = 27/465 (5%)
Query: 29 THDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLY 88
T D DL VIG+G GG A+ +AA G KV E D +GGTC+ GC+P K +++ SH
Sbjct: 2 TFDYDLFVIGAGSGGLAASKRAASYGAKVAIAEND-LVGGTCVIRGCVPKKLMVYGSHFP 60
Query: 89 HMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAP 148
+ + D G + G+ +++ + V+ L+ +K V L+ G T+V
Sbjct: 61 ALFE-DAAGYGWQVGKAELNWEHFITSIDKEVRRLSQLHISFLEKAGVELISGRATLVDN 119
Query: 149 NKVEVHGEKGVETVNTKNILIASGSEVTP-FPGVTFDEKQIITSTGALSLESVPKKMLVI 207
+ VEV GE+ + K ++ G + P PG+ + ITS L++ PK + +I
Sbjct: 120 HTVEV-GER--KFTADKILIAVGGRPIKPELPGMEYG----ITSNEIFHLKTQPKHIAII 172
Query: 208 GAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVL 267
G+G IG E + + LG+ VT I I G D ++ +Q+ ++ G++ V
Sbjct: 173 GSGYIGTEFAGIMRGLGSQVTQITRGDKILK-GFDEDIRTEIQEGMTNHGIRIIPKNVVT 231
Query: 268 GVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRG----- 322
+++ +K+ + G ++E + DV L++ GR P GLGL+ G+ + D
Sbjct: 232 AIEQVPEGLKISLS---GEDQEPIIADVFLVATGRVPNVDGLGLENAGVDVVDSSIEGPG 288
Query: 323 -----RIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH-FNYDAI 376
I VN QT+ P IYA+GDV L A EG + G F+++ I
Sbjct: 289 YSTMNAIAVNEYSQTSQPNIYAVGDVTDRLNLTPVAIGEGRAFADSEFGNNRREFSHETI 348
Query: 377 PSVIYTSPEVGWVGKTEEDLKKE--GRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTT 434
+ ++++P+ VG TE + + + A + + F + T + +K++ D T
Sbjct: 349 ATAVFSNPQASTVGLTEAEARAKLGDDAVTIYRTRFRPMYHSFTGKQERIMMKLVVDTKT 408
Query: 435 DVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAE 479
D +LG H++G E+I +A + GA +D HP+ AE
Sbjct: 409 DKVLGAHMVGENAAEIIQGVAIAVKMGATKKDFDATVGIHPSSAE 453
>UniRef50_A3ZHU0 Cluster: Probable pyridine nucleotide-disulfide
oxidoreductase YkgC; n=1; Campylobacter jejuni subsp.
jejuni 84-25|Rep: Probable pyridine nucleotide-disulfide
oxidoreductase YkgC - Campylobacter jejuni subsp. jejuni
84-25
Length = 451
Score = 176 bits (429), Expect = 1e-42
Identities = 129/456 (28%), Positives = 216/456 (47%), Gaps = 18/456 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTL-GGTCLNVGCIPSKALLHNSHLYHM- 90
++++IG G GG A K A LG KV +E+D + GGTC+NVGCIPSK+L+ NS
Sbjct: 5 EVIIIGFGKGGKTLAAKLAMLGKKVALIEEDENMYGGTCINVGCIPSKSLVKNSLCVDKN 64
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
A + KQ F + ++E K + L + L G + +
Sbjct: 65 ANWEIKQN--------FYYNAILEEKQLSAMLRQKNYDKLNALENITLYLGKASFINEKT 116
Query: 151 VEVHGEKGVETVNTKNILIASGSEVTPFPGVT-FDE-KQIITSTGALSLESVPKKMLVIG 208
+ + GEK V+ ++ I I +GS + P + D+ K ++TS ++ E++PK +++IG
Sbjct: 117 LLIQGEKEVQ-ISADRIYINTGS-IPIIPDIKGLDQSKNVLTSKELMAQENLPKHLVIIG 174
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
G I LE +Y G+ VT ++ + G D + A + + L + + +LG +
Sbjct: 175 GGYIALEFACIYANFGSKVTLLQRNDTFLGKE-DKDFADLIFQNLENKQIDIRLGVQFKE 233
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
+K K V + ++CD++L++ GR+ T GL DK GI LD RG I V++
Sbjct: 234 IKDFDQ--KSIVFFTQDHQDFEIECDMILLATGRKANTLGLSCDKAGIQLDKRGFIIVDD 291
Query: 329 KFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMP-VHFNYDAIPSVIYTSPEVG 387
+T IYA+GDV G + + D+ + + IP ++ P
Sbjct: 292 TLKTNKDSIYALGDVNGGLQFTYVSLDDYRIAYAPFRQQNYTKSKRKVIPYSVFIDPPFS 351
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG E++ G KV K P +A +A+ +T G +K + ++ D ILG +
Sbjct: 352 RVGLNEKESIDAGYRIKVVKLPVVAIPKAQVLKKTYGLLKAIINEENDEILGAMLFCEES 411
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
E+IN LA + + + + HPT +E+ +
Sbjct: 412 HEMINIVKLAMDTNLKYQVLRDQIYTHPTMSESFND 447
>UniRef50_A2C124 Cluster: Probable glutathione reductase; n=2;
Prochlorococcus marinus|Rep: Probable glutathione
reductase - Prochlorococcus marinus (strain NATL1A)
Length = 453
Score = 176 bits (429), Expect = 1e-42
Identities = 139/453 (30%), Positives = 211/453 (46%), Gaps = 17/453 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL+VIG+G GG AA KAA G V VE D +GGTC+ GC+P K L+ S L
Sbjct: 6 DLIVIGAGSGGLAAAKKAASYGASVAIVEGD-LVGGTCVIRGCVPKKLLVCGSSLLESFL 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
G + + + ++ V L K V L KG G N VE
Sbjct: 65 -SATSYGFDFDNLKIKSEVLLANVRKEVHRLNELHENFLNKANVELFKGWGEFRNSNCVE 123
Query: 153 VHGEKGVETVNT---KNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
V K ET+N + ILIA G P + TS L+S PKK+ ++GA
Sbjct: 124 VKDRKNGETLNELYGERILIAVGGRPKR-PSIE-GASLGWTSDDMFLLKSFPKKITIVGA 181
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
G I E + LG +VT + I G D E++ +L + + +G+ G K+ +
Sbjct: 182 GYIACEFACILHGLGVEVTQLVRGDRILR-GFDFELSSSLTEAMKNKGVNISFGEKISSL 240
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
K ++ + A K D + +L + GR P+ GL L++ GI + + +I V+++
Sbjct: 241 KGTPGSLIIKTNAGKE-----FDSNGLLFATGREPFLDGLKLEQAGIEILEN-KIKVDSE 294
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH-FNYDAIPSVIYTSPEVGW 388
+T + I+AIGDV L A DEG + G H NY+ +P +++ PE+
Sbjct: 295 GKTNISNIFAIGDVTDRINLTPVAIDEGRKFADRNYGESDHKVNYNFVPYAVFSQPEIAS 354
Query: 389 VGKTEED-LKKEGRA-YKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPG 446
VG TEE ++ G+ KV + F S++ ++ +K++ DK + +LG H+IG
Sbjct: 355 VGMTEEKAIQSIGKDNIKVYRSIFRPLSKSLPKTGSKCILKLIVDKNNNKVLGCHMIGDN 414
Query: 447 GGELINEAVLAQEYGAAAEDVARVCHAHPTCAE 479
E+I A ++ GA D HPT AE
Sbjct: 415 ASEIIQMASISLMLGAKKTDFDNTMALHPTIAE 447
>UniRef50_P77212 Cluster: Probable pyridine nucleotide-disulfide
oxidoreductase ykgC; n=17; Enterobacteriaceae|Rep:
Probable pyridine nucleotide-disulfide oxidoreductase
ykgC - Escherichia coli (strain K12)
Length = 441
Score = 176 bits (429), Expect = 1e-42
Identities = 124/455 (27%), Positives = 218/455 (47%), Gaps = 32/455 (7%)
Query: 35 VVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTL-GGTCLNVGCIPSKALLHNSHLYHMAKH 93
V+IG G G A+ A+ G +V +E+ + GGTC+N+GCIP+K L+H++ +H
Sbjct: 7 VIIGFGKAGKTLAVTLAKAGWRVALIEQSNAMYGGTCINIGCIPTKTLVHDAQ-----QH 61
Query: 94 DFKQRGIETGEVTFDFKKMMEYKANAVKGLTG-GIAMLFQKNKVNLVKGVGTIVAPNKVE 152
DF + ++ K V L L ++++ G + + +
Sbjct: 62 T-------------DFVRAIQRKNEVVNFLRNKNFHNLADMPNIDVIDGQAEFINNHSLR 108
Query: 153 VHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
VH +G ++ + I I +G++ V P PG+T + STG L+L+ +P + ++G G
Sbjct: 109 VHRPEGNLEIHGEKIFINTGAQTVVPPIPGIT-TTPGVYDSTGLLNLKELPGHLGILGGG 167
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
IG+E S++ G+ VT +E S+ D ++A + IL QG+ L V +
Sbjct: 168 YIGVEFASMFANFGSKVTILE-AASLFLPREDRDIADNIATILRDQGVDIILNAHVERIS 226
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
+ ++V E A+ L D +LI+ GR+P T L + GIA+++RG I V+ +
Sbjct: 227 HHENQVQVHSEHAQ------LAVDALLIASGRQPATASLHPENAGIAVNERGAIVVDKRL 280
Query: 331 QTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDA--IPSVIYTSPEVGW 388
TT I+A+GDV G + + D+ + + + G D +P ++ +P +
Sbjct: 281 HTTADNIWAMGDVTGGLQFTYISLDDYRIVRDELLGEGKRSTDDRKNVPYSVFMTPPLSR 340
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VG TEE ++ G +V P A RA+ +T G +K + D T +LG ++
Sbjct: 341 VGMTEEQARESGADIQVVTLPVAAIPRARVMNDTRGVLKAIVDNKTQRMLGASLLCVDSH 400
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
E+IN + + G + HP+ +E+L +
Sbjct: 401 EMINIVKMVMDAGLPYSILRDQIFTHPSMSESLND 435
>UniRef50_UPI00015BD547 Cluster: UPI00015BD547 related cluster; n=1;
unknown|Rep: UPI00015BD547 UniRef100 entry - unknown
Length = 452
Score = 175 bits (426), Expect = 2e-42
Identities = 140/464 (30%), Positives = 221/464 (47%), Gaps = 29/464 (6%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
+ D++ IG+G G Y A + A+ G V+ V+K + G CL GC+PSKA+ H Y
Sbjct: 3 EVDVLTIGAGGGAYPGAFRLAKAGFSVLMVDKKGVMSGNCLAEGCVPSKAIREQIHTY-- 60
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGI--AMLFQKNKVNLVKGVGTIVAP 148
+ + ++ D+K ++ K + V+ + + L + L+KGV
Sbjct: 61 ----LRFKAFSKKDIDIDYKDIIA-KKDEVQNIRYKLHEEELKAFKNLKLMKGVARFKDE 115
Query: 149 NKVEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLES----VPKKM 204
+ V V +KG ET+ K I+IASG++V F ++ ITST L +PK+
Sbjct: 116 HTVVVESDKGEETIKAKYIIIASGADV--FVPPIKGKEYAITSTDIYKLNPNLTYMPKEF 173
Query: 205 LVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGT 264
++G G IGLE + LG++V E L + GID +TL K L K K+ T
Sbjct: 174 AIVGGGYIGLETAFYFANLGSNVYIFEKLDRV-LAGIDKYATQTLLKYLPK---NIKIFT 229
Query: 265 KVLGVKKEGSTIKVDVEAAKGGNK-EVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGR 323
V V++ G K V K + + ++ D VL+++GR+P G DK L
Sbjct: 230 SV-EVQEIGLKDKKKVVYYKQDDTVKSIEVDEVLMAVGRKPIIPE-GADKF---LKISKA 284
Query: 324 IPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI--KGMPVHF-NYDAIPSVI 380
I VN QT +P IYA GDV L H A + IVC I P+ + +++ +P +
Sbjct: 285 IEVNRACQTNIPHIYASGDVNGKIPLFHTATRQSIVCAYNIMANNTPIDYADFENVPFTV 344
Query: 381 YTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGT 440
+T P + +VG T+E + F +SRA+ E EG +K+ D + ++G
Sbjct: 345 FTIPAMAFVGITKEKAESLNMDIVETSFDLKEDSRAEIYSE-EGELKLFFDAKSLKLVGA 403
Query: 441 HIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
I+G +L++ LA + GA A D+ HP E + +A
Sbjct: 404 SIVGIDAEQLVSHLGLAIKLGATARDLVEYQDQHPMTQECISKA 447
>UniRef50_Q83N49 Cluster: Pyridine nucleotide-disulphide
oxidoreductase class I; n=3; Micrococcineae|Rep:
Pyridine nucleotide-disulphide oxidoreductase class I -
Tropheryma whipplei (strain Twist) (Whipple's bacillus)
Length = 473
Score = 175 bits (426), Expect = 2e-42
Identities = 135/461 (29%), Positives = 220/461 (47%), Gaps = 17/461 (3%)
Query: 34 LVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSH--LYHMA 91
+VVIG GPGGY AA+ A LG VV +E +GG+ +PSK L+ ++ ++
Sbjct: 17 IVVIGGGPGGYSAALSGALLGADVVLIENQ-AVGGSATLTDVVPSKTLIASAERAVFVAQ 75
Query: 92 KHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
DF R V+ D + + + + + V +V G + PN+V
Sbjct: 76 GADFGIRFQNC--VSADIGHINRRIMDLTRAQSADMFSTLTGAGVRVVYGHAALDGPNRV 133
Query: 152 --EVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
V G++ E +++A+GS P D K+I+T +LE VP+ ++V+G+
Sbjct: 134 LVSVSGQEKYEFF-ANTVVVATGSSPRVLPNAIPDGKRILTWKQLYTLEQVPEHIIVVGS 192
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
GV G E S ++ LG++VT + + G D + A +Q++ GMK L +
Sbjct: 193 GVTGAEFASAFRNLGSEVTLVSSRDRVLPGG-DEDAADLIQEVFINSGMK--LLNRARAQ 249
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
V V G C L+++G P T G+GL+ IAL+ GRI VN
Sbjct: 250 AAAACNGGVVVTLTDGTEVRGTHC---LMAVGSVPNTSGIGLETANIALNPAGRITVNRV 306
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH-FNYDAIPSVIYTSPEVGW 388
++VPG+YA GD LA AE +G V V G + + S ++T+PE+
Sbjct: 307 ACSSVPGVYAAGDCSDFLPLASVAEMQGQVAVYHAMGENANPIELKNLASTVFTTPEIAT 366
Query: 389 VGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
VG++E+ + K RA + K NSRAK G GFVK++ + T +LG ++ P
Sbjct: 367 VGRSEKAIDK-ARATAL-KVDLATNSRAKILGIKTGFVKMIVSRETGTVLGGVVVAPNAS 424
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAY 489
+LI +A + +A+ +++ +P+ +L A A++
Sbjct: 425 DLIFPISVAVQNRLSADQLSQSFAVYPSLTISLWHAARASH 465
>UniRef50_Q5FQ43 Cluster: Glutathione reductase; n=3;
Acetobacteraceae|Rep: Glutathione reductase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 483
Score = 175 bits (426), Expect = 2e-42
Identities = 140/466 (30%), Positives = 217/466 (46%), Gaps = 25/466 (5%)
Query: 24 RQYATTHDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLH 83
R+ D DL VIG+G GG A AAQ G +V E+ GGTC+N+GC+P K +++
Sbjct: 16 RKAGMMQDFDLFVIGAGSGGVRCARIAAQNGARVAIAERRHW-GGTCVNLGCVPKKLMVY 74
Query: 84 NSHLYHMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVG 143
+ Y D G + V D+ ++ K ++ L + +K V L G
Sbjct: 75 AAE-YGREIADAPSYGWDVKPVAHDWSTLISAKDREIERLNRIYVSMLEKAGVTLFTGDA 133
Query: 144 TIVAPNKVEVHGEK-----GVETVNTKNILIASGSEVTPF--PGVTFDEKQIITSTGALS 196
+ V + VE+ + V+ V KNI+IA+GS T PG + I S A
Sbjct: 134 SFVDAHTVEIGPSELAPDASVQRVRAKNIVIATGSTPTRLNIPGA----EHAIVSDDAFH 189
Query: 197 LESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQ 256
L P+++ VIG+G IG+E ++ LG+ V + F + G D E+ L ++L
Sbjct: 190 LADRPERVAVIGSGYIGIEFAGIFAGLGSKVDLV-FRQQLPLRGFDHEMRAHLSELLPLN 248
Query: 257 GMKFKLGTKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGI 316
G+K G ++K ++ +E GG +V++ D V ++ GR P L L G+
Sbjct: 249 GIKAHPGRSPERIEKVADGYRLHLE---GG--DVIETDCVFMATGRHPNLAPLKLGNAGV 303
Query: 317 ALDDRGRIPVNNKFQTT-VPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH-FNYD 374
A D GRIP TT V GIYAIGDV L A EG + E + G P +++
Sbjct: 304 ATWD-GRIPAKPDDATTNVAGIYAIGDVTDTYNLTPTAIAEGHILAERLFGEPGREWSFA 362
Query: 375 AIPSVIYTSPEVGWVGKTEED-LKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKT 433
P ++ S + VG +EE+ ++ F + + + G+T +K++ D
Sbjct: 363 TTPKAVFFSQPLATVGLSEEEAVQSHDVDIYTSSFTPMRQTLSGRKGKT--LMKLVVDAK 420
Query: 434 TDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAE 479
+ ++LG H+IGP E+I +A D R HPT AE
Sbjct: 421 SKIVLGAHMIGPDAPEIIQGLAIAITAKLTKRDFDRTIGLHPTSAE 466
>UniRef50_Q97PL8 Cluster: Oxidoreductase, pyridine
nucleotide-disulfide, class I; n=29; Bacteria|Rep:
Oxidoreductase, pyridine nucleotide-disulfide, class I -
Streptococcus pneumoniae
Length = 438
Score = 174 bits (424), Expect = 4e-42
Identities = 128/456 (28%), Positives = 203/456 (44%), Gaps = 31/456 (6%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTL-GGTCLNVGCIPSKALLHNSHLYHMA 91
DL+VIG G G A K A G KV VE+ + GGTC+N+GCIP+K LL
Sbjct: 5 DLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCINIGCIPTKTLL--------- 55
Query: 92 KHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
E F++++ K L G V++ ++ +
Sbjct: 56 ---------VAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLSNKVI 106
Query: 152 EVHGEKGVETVNTKNILIASG--SEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
E+ + + + I+I +G S V P PG+ K I STG SL+ +P+K+ ++G
Sbjct: 107 EIQAGDEKKELTAETIVINTGAVSNVLPIPGLA-TSKNIFDSTGIQSLDKLPEKLGILGG 165
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGV 269
G IGLE +Y +LG+ VT ++ L + + +A ++ + + G++ +
Sbjct: 166 GNIGLEFAGLYNKLGSKVTVLDALDTFLPRA-EPSIAALAKQYMEEDGIELLQNIHTTEI 224
Query: 270 KKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNK 329
K +G + V E E D +L + GR+P + L L+ I L +RG I V+
Sbjct: 225 KNDGDQVLVVTE------DETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVDKH 278
Query: 330 FQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDA--IPSVIYTSPEVG 387
QT VPG++A+GDV G + + D+ V + G + D +P+ ++ +P +
Sbjct: 279 CQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFITPALS 338
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG TE Y V + P A R NG+ G K + + T ILG I G
Sbjct: 339 QVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGASIFSEGS 398
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
E+IN +A + + HPT AE L +
Sbjct: 399 QEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLND 434
>UniRef50_Q60151 Cluster: Glutathione reductase; n=31; Bacteria|Rep:
Glutathione reductase - Streptococcus thermophilus
Length = 450
Score = 173 bits (421), Expect = 9e-42
Identities = 135/451 (29%), Positives = 202/451 (44%), Gaps = 16/451 (3%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
D +VIG G GG +A +AA G KV+ E +GGTC+NVGC+P K + + + +
Sbjct: 6 DYIVIGGGSGGIASANRAAMHGAKVILFE-GKEVGGTCVNVGCVPKKVMWYGAQVAETLH 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVE 152
+ G + FDF + + + + G F N V V V P+ VE
Sbjct: 65 RYAGEYGFDVTINNFDFATLKANRQAYIDRIHGSFERGFDSNGVERVYEYARFVDPHTVE 124
Query: 153 VHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVI 212
V GE +ILIA+G +P + E I TS G L+ VPK+ VIGAG I
Sbjct: 125 VAGE----LYTAPHILIATGGHPL-YPNIPGSEYGI-TSDGFFELDEVPKRTAVIGAGYI 178
Query: 213 GLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKE 272
+E+ V LG+D T + D ++ L ++K G + V K
Sbjct: 179 AVEVAGVLNALGSD-THLFVRKDRPLRTFDKDIIDVLVDEMAKSGPTLHMHANATEVVKN 237
Query: 273 GSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQT 332
D N+E + D ++ ++GR T G GL+K G+ L +RG I + T
Sbjct: 238 AD----DSLTISFDNEETITVDCLIWAVGRAANTSGFGLEKTGVELTERGNIYSDEFENT 293
Query: 333 TVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI--KGMPVHFNYDAIPSVIYTSPEVGWVG 390
+VPGIYA+GDV L A G E + + +Y + +V+++ P +G +G
Sbjct: 294 SVPGIYALGDVTGKLDLTPVAVKAGRQLSERLFNNKVDAKLDYTDVATVVFSHPAIGAIG 353
Query: 391 KTEED-LKKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGG 448
TEE + K G KV K F A + +K+++ + I+G H IG G
Sbjct: 354 LTEEKAIAKYGAENIKVYKSSFTPMYTALGDNRQLSTMKLVTLGEDEKIIGLHGIGYGVD 413
Query: 449 ELINEAVLAQEYGAAAEDVARVCHAHPTCAE 479
E+I +A + GA D HPT +E
Sbjct: 414 EMIQGFSVAIKMGATKADFDNTVAIHPTGSE 444
>UniRef50_Q5WE89 Cluster: Acetoin dehydrogenase E3 component; n=1;
Bacillus clausii KSM-K16|Rep: Acetoin dehydrogenase E3
component - Bacillus clausii (strain KSM-K16)
Length = 399
Score = 173 bits (420), Expect = 1e-41
Identities = 123/393 (31%), Positives = 197/393 (50%), Gaps = 23/393 (5%)
Query: 99 GIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVEVHGEKG 158
GIET V D K+ + ++ L+ GIA L +KN++ +G TI ++ G
Sbjct: 18 GIETSVVQVDDSKLFRRQNAIIQSLSAGIAQLLKKNRITFFQGEATIDGSQQLVCDGH-- 75
Query: 159 VETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVIGLELGS 218
+ ++N+L+A+G + P + +T+ S+PK +++IG GVI +EL
Sbjct: 76 --LIQSENLLLATGGKPFIPPIAQLETIDYMTTDTFFQQTSLPKSLVIIGGGVIAVELAF 133
Query: 219 VYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKEGSTIKV 278
G VT +E + I D + ++K L ++G++ + T V+ ++ G +
Sbjct: 134 AVSPFGTKVTILEVASDILQTE-DEQARAVVKKQLQQRGVEIE--TNVV-IENVGQGLVR 189
Query: 279 DVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGR-IPVNNKFQTTVPGI 337
AA + +L++ GRRP T+ D + + D R I VN ++T+ GI
Sbjct: 190 TANAA-------FPFERLLVAAGRRPNTELA--DALHLQKDANNRFIEVNPYYETSKKGI 240
Query: 338 YAIGDVIHGPMLAHKAEDEGIVCVE---GIKGMPVHFNYDAIPSVIYTSPEVGWVGKTEE 394
YAIGDVI LAH A EGI VE GIK P+ + IP +YT PE+ G +E+
Sbjct: 241 YAIGDVIGKYELAHAASAEGIAAVEHMAGIKQQPI--DELGIPRCVYTDPEIASFGLSEK 298
Query: 395 DLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELINEA 454
+ K+ G KV AN +A G+T GFVK++++K +LG I+G ELI E
Sbjct: 299 EAKERGYDVKVSFSANAANGKALAEGDTSGFVKLITEKKYGELLGAVIVGKHATELIGEL 358
Query: 455 VLAQEYGAAAEDVARVCHAHPTCAEALREANLA 487
+ + ++ ++ HAHPT AE + E+ LA
Sbjct: 359 LATRVSEGTISELQQLIHAHPTIAEVIGESALA 391
>UniRef50_A7IDF4 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region precursor; n=9;
Alphaproteobacteria|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region precursor -
Xanthobacter sp. (strain Py2)
Length = 448
Score = 173 bits (420), Expect = 1e-41
Identities = 130/456 (28%), Positives = 209/456 (45%), Gaps = 20/456 (4%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL +IG+G V A + G V + P GGTC GC P K ++ + A
Sbjct: 6 DLAIIGTGTAAIVTAHRVRAAGWSVAVADFRP-FGGTCALRGCDPKKMMVGGAEA---AD 61
Query: 93 HDFKQ--RGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNK 150
H ++ RGIE G+ T D+ +M +K + + F ++ G + PN
Sbjct: 62 HAWRMSGRGIE-GDATLDWTGLMAFKRSFTDPVPQKREKAFADKGIHAFHGHVRFIGPNA 120
Query: 151 VEVHGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAG 210
+E GE+ + I+IA+G+E P G+ E+ +IT+ G L LES+P++++++G G
Sbjct: 121 LEFGGER----IEADRIVIAAGAEAVPL-GIP-GEQHLITNEGFLELESLPERIVLVGGG 174
Query: 211 VIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVK 270
I E + R GA VT ++ + D ++ L S++G+ + V ++
Sbjct: 175 YIAAEFSHIAARAGAQVTILQHGKRMLKQ-FDPDLVGWLMDKFSERGINVRTQAGVTAIE 233
Query: 271 KEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKF 330
K +V + G + +D D+V+ + GR P L LD G GR+ +N
Sbjct: 234 KVSDGYRVRADCPDG--ELDMDADLVVHAAGRAPALATLDLD-AGSVKHHNGRLALNGFL 290
Query: 331 QTTV-PGIYAIGDV--IHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVG 387
Q+ P +YA GD + P+ + D +V + G V Y +PSV +T P +
Sbjct: 291 QSVSNPAVYAAGDAAGLGPPLTPVSSHDAKVVSANLLNGNTVRPEYTGVPSVAFTIPPIA 350
Query: 388 WVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 447
VG +E +++G +V A+ ET K L D TD ILG H++GP
Sbjct: 351 AVGMSEAKAREKGLNVRVKTERVDGWFTARQQAETVYGFKTLVDADTDRILGAHLVGPHA 410
Query: 448 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
E+IN LA G AE + A+P+ A + E
Sbjct: 411 DEVINIFALAIRQGLTAEQLKTTMFAYPSGASDIGE 446
>UniRef50_A4YFQ3 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=1; Metallosphaera
sedula DSM 5348|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Metallosphaera
sedula DSM 5348
Length = 444
Score = 173 bits (420), Expect = 1e-41
Identities = 134/459 (29%), Positives = 221/459 (48%), Gaps = 36/459 (7%)
Query: 31 DADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHM 90
D D +++G G GY A + ++ GMKV+ ++ LGG CL GCIPSK + +
Sbjct: 3 DFDAIILGGGGAGYTTAFELSRGGMKVLMLDPKGVLGGNCLYEGCIPSKTYWYGARQLET 62
Query: 91 AKHDFKQRGIETGEVTFDFKKMMEYKANAV-KGLTGGIAMLFQKNKVNLVKGVGTIVAPN 149
AK + + F K++++K + + + + + G IV N
Sbjct: 63 AKR------VPFMKAEISFPKLVDWKDQVQERRFRQHDDEIREHESLTFLAKSGIIVDQN 116
Query: 150 KVEVHGEKGVETVNTKNILIASGSE-VTPF---PGVTFDEKQIITSTGALSLESVPKKML 205
V+V +TK ++IA+G++ V P G+T E ++ T + VP+K
Sbjct: 117 HVKVEDR----VYSTKYLVIATGADPVIPKGYEAGITTHEL-LMPKT---RIREVPRKFA 168
Query: 206 VIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTK 265
++G G IG+E+ S++ RLG++VT F + + + EV L++ L G+K + +
Sbjct: 169 IVGGGYIGVEMASIFARLGSEVTL--FASHLIKE-VSQEVQSLLERELINAGVKI-VKER 224
Query: 266 VLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIP 325
GV KE + V KG + D VL+++GRRP T + GI L +G I
Sbjct: 225 STGVLKENGKV---VLTEKG---KYQGFDEVLVAVGRRPNTSSVN----GIPLGKKGEIE 274
Query: 326 VNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI---KGMPVHFNYDAIPSVIYT 382
++ + IYA GDV ML H A EG V + I V +Y+A+P +YT
Sbjct: 275 TTPGMRSAIENIYAPGDVNGKFMLFHVAVLEGWVTAQNILEGNREVVEMDYNAVPFAVYT 334
Query: 383 SPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHI 442
P+V WVG +E G + ++ +SRA+ +G EG+++V+ ++ + ILG +
Sbjct: 335 FPQVAWVGLWKEQAIARGFDVETRRYDLSLDSRAQIDGFAEGWMEVVIERGSQRILGAQV 394
Query: 443 IGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 481
+G LI E LA + ++AR+ HPT E +
Sbjct: 395 VGEDADMLIGELALAVGERLTSYELARISQPHPTQLEQI 433
>UniRef50_A4AEI6 Cluster: Putative oxidoreductase; n=1; marine
actinobacterium PHSC20C1|Rep: Putative oxidoreductase -
marine actinobacterium PHSC20C1
Length = 479
Score = 172 bits (418), Expect = 2e-41
Identities = 138/463 (29%), Positives = 218/463 (47%), Gaps = 28/463 (6%)
Query: 33 DLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAK 92
DL+VIGSG G VA+ AA+ G +V+ VE+ LGG CL GC+PSK+L+ +H H+A+
Sbjct: 6 DLIVIGSGSAGIVASRTAARFGARVLLVERH-RLGGDCLWTGCVPSKSLIAAAHAAHIAR 64
Query: 93 HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTG-GIAMLFQKNKVNLVKGVGTIVAPNKV 151
++ G+ +T DF + M + +AV + A F + + G N +
Sbjct: 65 TS-ERFGVTAENLTIDFARAMSHVRDAVATIEPHDSAEAFATLGIEVASGDARFTGRNSL 123
Query: 152 EVHGEKGVETVNT-KNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
E+ G T +T +IA+G+E + F G D ++TS L+ +PK+++V+G
Sbjct: 124 EIDG-----TPHTFVQAVIATGTEPQLPEFAGA--DSIDMLTSDTIWQLDELPKRLVVLG 176
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQG---MKFKLGTK 265
G IG ELG RLG+ VT + I D + LQ + G + + T
Sbjct: 177 GGPIGSELGQAMARLGSAVTIVNRNARILS-SEDERSSAILQASFDRDGITVLNDRSATS 235
Query: 266 VLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIP 325
V + + +D G + L D +L ++GR L + G+A+ G I
Sbjct: 236 VTSNDRLAGELVLD-----DGTR--LPFDRLLAAVGRSTRLGKLAPEAAGVAITQHGYIK 288
Query: 326 VNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVC-VEGIKGMPVHFNYDAIPSVIYTSP 384
V+ +TT I+A GD P +H A G V G+ FN +P V +T+P
Sbjct: 289 VDASLRTTNKRIWAAGDAAGLPKFSHVAGVSGSVAGTNAALGLRRKFNEQVVPRVTFTAP 348
Query: 385 EVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 444
E+ VG D EG+ ++V + RA + +G+ +++ D V+ GT I+G
Sbjct: 349 EIAAVGMAPVD-AVEGK-HRVYTAEHASTDRAIAEADDDGYAQIVVDNRGRVLGGT-IVG 405
Query: 445 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 487
P GE + E +A +A HA+PT +AL A +A
Sbjct: 406 PRAGESLGELTVAVSAKLTTSTLAGATHAYPTFTDALWNAAIA 448
>UniRef50_Q4JCC0 Cluster: Dihydrolipoamide dehydrogenase; n=4;
Sulfolobaceae|Rep: Dihydrolipoamide dehydrogenase -
Sulfolobus acidocaldarius
Length = 414
Score = 172 bits (418), Expect = 2e-41
Identities = 139/450 (30%), Positives = 224/450 (49%), Gaps = 44/450 (9%)
Query: 34 LVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAKH 93
+VVIGSGP G +AI ++ LG KV VEK+ LGGTC+ GCIPSKA+LH L +
Sbjct: 3 IVVIGSGPAGLYSAITSSSLGNKVTLVEKEDRLGGTCVLYGCIPSKAMLHPLILSSGIE- 61
Query: 94 DFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKVEV 153
K +G ++ F+FK++ E NAV ++ G + +K V+++ G I+ N VEV
Sbjct: 62 --KVKG--NSKIEFNFKEISELGINAVNRVSKGTEYMLEKYNVDIIHG-RAILKGNSVEV 116
Query: 154 HGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVIG 213
+G +T+++ I+IA+G+ V P + I S L+ +K+++IG GV G
Sbjct: 117 NG----QTLSSDKIIIATGT-VKP------QVQGSIASDDLPYLDRDFQKVVIIGGGVGG 165
Query: 214 LELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLGVKKEG 273
+E G + + LG ++ +E ++ D ++ ++ K G LG +V +++
Sbjct: 166 VEYGWLLRALGKEIFVVE-KENLLLPRHDPDLRNSVTYTFRKMGFSLLLGKEVKKIERN- 223
Query: 274 STIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNNKFQTT 333
KV ++ K ++ D++L+S GR G G+ D I VN +T
Sbjct: 224 ---KVVLDDGK-----EIEGDIILMSFGRTANVNGF----EGVPHDK--WIKVNEFMETE 269
Query: 334 VPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGKTE 393
+ G+YA GDV G AH+A +GI G+ + D I VIYT P++ +VG T
Sbjct: 270 IRGVYAAGDVT-GSFTAHEAISKGITAGYNASGIASRYRSDGIVKVIYTKPQIAYVGDT- 327
Query: 394 EDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELINE 453
G+ K+ + +RA ETEGFVKV + D ++G E+++
Sbjct: 328 ----TRGKCVKLN---MASLTRAIAEKETEGFVKVCVE--DDKVIGAVAFSERAEEIVSV 378
Query: 454 AVLAQEYGAAAEDVARVCHAHPTCAEALRE 483
LA Y +++A HP+ E + E
Sbjct: 379 LGLAIRYNIKVKELAEYPFPHPSYLETINE 408
>UniRef50_A4MI92 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=1; Geobacter
bemidjiensis Bem|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Geobacter
bemidjiensis Bem
Length = 449
Score = 171 bits (415), Expect = 5e-41
Identities = 123/451 (27%), Positives = 220/451 (48%), Gaps = 22/451 (4%)
Query: 32 ADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMA 91
AD++VIG+G G+ A+ A + G + V+V D GGTC GC P K L+ + + H+
Sbjct: 5 ADVLVIGTGTAGFTLAL-ACRKGGRQVAVVDDKPYGGTCGRNGCEPEKYLMQAAQVVHLT 63
Query: 92 KHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPNKV 151
+ +GI T D+ ++ K+ G+ FQ+ + + G ++P V
Sbjct: 64 RQ-MSGQGI-TVPAAMDWPALIRSKSAFSNGVPERTERAFQQAGIKMYFGTAHFLSPETV 121
Query: 152 EVHGEKGVETVNTKNILIASGSEVTP--FPGVTFDEKQIITSTGALSLESVPKKMLVIGA 209
+ E TV + I+IA+G+ P FPG ++ ++ + ++++P+++L IG
Sbjct: 122 AIGSET---TVRAETIVIATGARPAPLDFPGAGL----VVETSDFMEMKNLPRRVLFIGG 174
Query: 210 GVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLG-TKVLG 268
G + L G V + GADVT ++ + D E+A+ K +G+ G T +
Sbjct: 175 GCLALSFGHVARAAGADVTILQRGERVLK-NFDLEMAQLAAKAARARGINIVTGITAAMA 233
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVNN 328
K +G+ + KGG E D+++ + GR P + + +A RG + VN
Sbjct: 234 EKVQGAFMTY----GKGGCTEAFPSDLIVNTSGRIPDLDPVDPEAGAVARSARG-VTVNE 288
Query: 329 KFQTTV-PGIYAIGDVIHGP-MLAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPE 385
Q+ P ++AIGD P +L+ A+ E V + I G +Y +PS+ P
Sbjct: 289 FLQSVSNPRVWAIGDACDSPYLLSTVADMEAEVAADNILTGNRRRPDYQGVPSMAQAQPP 348
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGP 445
+ +VG TE ++ G+ +++ + + ++ G+ GF KVL ++ T ILG H++G
Sbjct: 349 LSFVGLTEAQARQSGKKFRINRGSTDSWPSSRRIGQQGGFYKVLIEEETGKILGAHLLGQ 408
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPT 476
GE IN LA ++G + ++ ++ +PT
Sbjct: 409 NAGETINIFALALKFGISNSELRQILWTYPT 439
>UniRef50_Q17745 Cluster: Thioredoxin reductase 1; n=6;
Bilateria|Rep: Thioredoxin reductase 1 - Caenorhabditis
elegans
Length = 667
Score = 171 bits (415), Expect = 5e-41
Identities = 143/496 (28%), Positives = 233/496 (46%), Gaps = 32/496 (6%)
Query: 24 RQYATTHDADLVVIGSGPGGYVAAIKAAQLGMKVVS---VEKDPT-----LGGTCLNVGC 75
+++ H DL+VIG G GG AA +A++LG KV V+ P LGGTC+NVGC
Sbjct: 165 KEWLRDHTYDLIVIGGGSGGLAAAKEASRLGKKVACLDFVKPSPQGTSWGLGGTCVNVGC 224
Query: 76 IPSKALLHNSHLYHMAKHDFKQRG--IETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQK 133
IP K L+H + L + HD K+ G + G+V + + + + + L G + ++
Sbjct: 225 IPKK-LMHQASLLGHSIHDAKKYGWKLPEGKVEHQWNHLRDSVQDHIASLNWGYRVQLRE 283
Query: 134 NKVNLVKGVGTIVAPNKVEV-HGEKGVETVNTKNILIASGSEVTPFPGVTFDEKQIITST 192
V + G P ++ + +K VE + LI++G +P + ++ ITS
Sbjct: 284 KTVTYINSYGEFTGPFEISATNKKKKVEKLTADRFLISTGLR-PKYPEIPGVKEYTITSD 342
Query: 193 GALSLESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKI 252
L P K L +GA + LE G DVT + + SI G D ++A+ ++K
Sbjct: 343 DLFQLPYSPGKTLCVGASYVSLECAGFLHGFGFDVTVM--VRSILLRGFDQDMAERIRKH 400
Query: 253 LSKQGMKFKLG--TKV--LGVKKEGSTIKVDVEAAK-----GGNKEVLD-CDVVLISIGR 302
+ GMKF+ G T++ + K + K V K G +EV + + +L++IGR
Sbjct: 401 MIAYGMKFEAGVPTRIEQIDEKTDEKAGKYRVFWPKKNEETGEMQEVSEEYNTILMAIGR 460
Query: 303 RPYTKGLGLDKVGIALDDRGRIPVNNKFQTTVPGIYAIGDVIHG-PMLAHKAEDEGIVCV 361
T +GL +G+ ++ + TT+P +YAIGDV+ G P L A G V +
Sbjct: 461 EAVTDDVGLTTIGVERAKSKKVLGRREQSTTIPWVYAIGDVLEGTPELTPVAIQAGRVLM 520
Query: 362 EGI-KGMPVHFNYDAIPSVIYTSPEVGWVGKTEED-LKKEGRAYKV---GKFPFLANSRA 416
I G YD IP+ ++T E G G +EED + K G+ + F L + +
Sbjct: 521 RRIFDGANELTEYDQIPTTVFTPLEYGCCGLSEEDAMMKYGKDNIIIYHNVFNPLEYTIS 580
Query: 417 KTNGETEGFVKVLSDKT-TDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHP 475
+ + ++K++ + + ++G HI+ P GE+ +A + A D R+ HP
Sbjct: 581 ERMDKDHCYLKMICLRNEEEKVVGFHILTPNAGEVTQGFGIALKLAAKKADFDRLIGIHP 640
Query: 476 TCAEALREANLAAYSG 491
T AE L G
Sbjct: 641 TVAENFTTLTLEKKEG 656
>UniRef50_P42770 Cluster: Glutathione reductase, chloroplast
precursor; n=83; cellular organisms|Rep: Glutathione
reductase, chloroplast precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 565
Score = 171 bits (415), Expect = 5e-41
Identities = 135/464 (29%), Positives = 214/464 (46%), Gaps = 29/464 (6%)
Query: 30 HDADLVVIGSGPGG---------YVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKA 80
+D DL IG+G GG + A+ +L +S + +GGTC+ GC+P K
Sbjct: 86 YDFDLFTIGAGSGGVRASRFATSFGASAAVCELPFSTISSDTAGGVGGTCVLRGCVPKKL 145
Query: 81 LLHNSHLYHMAK--HDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNL 138
L++ S H + H F + ET E + D+ ++ K ++ LTG + K V L
Sbjct: 146 LVYASKYSHEFEDSHGFGWK-YET-EPSHDWTTLIANKNAELQRLTGIYKNILSKANVKL 203
Query: 139 VKGVGTIVAPNKVEVHGEKGVETVNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALS 196
++G G ++ P+ V+V G+ T+NILIA G + PG F I S AL
Sbjct: 204 IEGRGKVIDPHTVDVDGK----IYTTRNILIAVGGRPFIPDIPGKEF----AIDSDAALD 255
Query: 197 LESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQ 256
L S PKK+ ++G G I LE ++ L +V + G D +V + + +S +
Sbjct: 256 LPSKPKKIAIVGGGYIALEFAGIFNGLNCEVHVFIRQKKVLR-GFDEDVRDFVGEQMSLR 314
Query: 257 GMKFKLGTKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGI 316
G++F + K G ++ +KG V V+ + GR+P TK LGL+ VG+
Sbjct: 315 GIEFHTEESPEAIIKAGDG-SFSLKTSKG---TVEGFSHVMFATGRKPNTKNLGLENVGV 370
Query: 317 ALDDRGRIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGI-KGMPVHFNYDA 375
+ G I V+ QT+VP I+A+GDV L A EG + + + P +Y A
Sbjct: 371 KMAKNGAIEVDEYSQTSVPSIWAVGDVTDRINLTPVALMEGGALAKTLFQNEPTKPDYRA 430
Query: 376 IPSVIYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTD 435
+P +++ P +G VG TEE ++ V F + F+K++ T+
Sbjct: 431 VPCAVFSQPPIGTVGLTEEQAIEQYGDVDVYTSNFRPLKATLSGLPDRVFMKLIVCANTN 490
Query: 436 VILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAE 479
+LG H+ G E+I +A + G D HPT AE
Sbjct: 491 KVLGVHMCGEDSPEIIQGFGVAVKAGLTKADFDATVGVHPTAAE 534
>UniRef50_Q0C555 Cluster: Pyridine nucleotide-disulfide
oxidoreductase; n=2; Hyphomonadaceae|Rep: Pyridine
nucleotide-disulfide oxidoreductase - Hyphomonas
neptunium (strain ATCC 15444)
Length = 477
Score = 170 bits (413), Expect = 8e-41
Identities = 138/470 (29%), Positives = 218/470 (46%), Gaps = 25/470 (5%)
Query: 29 THDADLVVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLY 88
T ADL VIG+G G AA AA LG+KVV EK +GG CLN GC+PSKAL+ + +
Sbjct: 6 TLKADLAVIGAGSAGLSAAAGAAMLGLKVVLFEKHE-MGGDCLNFGCVPSKALISAAKIA 64
Query: 89 HMAKHDFKQRGIETGEVTFDFKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAP 148
H+ + + GI ++ + KA+ V+G IA + + + +G+G V
Sbjct: 65 HVPEEAVRY-GISLPPAVVNWDAV---KAH-VRGAIETIAPIDSQERF---EGLGCTVIR 116
Query: 149 NKVEVHGEKGVET----VNTKNILIASGSE--VTPFPGVTFDEKQIITSTGALSLESVPK 202
+ + + V + I+I++GS + P PG+ ++ T+ S P
Sbjct: 117 EAARFEDKNTLVSDSVRVKARRIIISTGSRAIIPPVPGL--EDVPYFTNETIFSAPDFPH 174
Query: 203 KMLVIGAGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKL 262
+++++G G IGLEL + RLG+ VT +E ++ D AK + +G+
Sbjct: 175 ELIILGGGPIGLELAQAFSRLGSKVTVVEMGRAL--PRSDAAHAKIAVDAVRAEGVTILE 232
Query: 263 GTKVLGVKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRG 322
G K + I V E +G ++ +LI+ GR+ T GL L+K G+ ++G
Sbjct: 233 GHKATRISGGPGNISVKAEGPEG--DVMIAGSHILIATGRQAVTDGLDLEKGGVDFTNKG 290
Query: 323 RIPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCV-EGIKGMPVHFNYDAIPSVIY 381
+ + P ++A+GD+ H A V V + +P+V Y
Sbjct: 291 VTVSDTLRSKSNPRVWALGDIAGHGQFTHLAGWHSSVFVRRAFFKQGSKASSLPLPAVTY 350
Query: 382 TSPEVGWVGKTE-EDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGT 440
TSPEV VG TE E +K G A K FPF N RA +T G K++ K ++G
Sbjct: 351 TSPEVAQVGLTEAEAREKFGDAVKTSAFPFHDNDRAIAEAKTLGEAKLVIHK--GKLVGA 408
Query: 441 HIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYS 490
I+G G G++I LA G + +PT E ++ A A ++
Sbjct: 409 SIVGEGAGDIIQMVGLAMSNGLKLTALTNFISPYPTRTEVVKRAASAYFT 458
>UniRef50_Q31FJ0 Cluster: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase; n=1;
Thiomicrospira crunogena XCL-2|Rep: FAD-dependent
pyridine nucleotide-disulphide oxidoreductase -
Thiomicrospira crunogena (strain XCL-2)
Length = 469
Score = 169 bits (412), Expect = 1e-40
Identities = 130/459 (28%), Positives = 220/459 (47%), Gaps = 28/459 (6%)
Query: 35 VVIGSGPGGYVAAIKAAQLGMKVVSVEKDPTLGGTCLNVGCIPSKALLHNSHLYHMAKHD 94
+++G+G G A + + V + G TC VGC+PSKAL+H + +H KH
Sbjct: 7 IILGAGSSGLTALGRIRRETDDFVMINGG-AFGTTCARVGCMPSKALIHCAEHFHARKH- 64
Query: 95 FKQRGIETGE-VTFD----FKKMMEYKANAVKGLTGGIAMLFQKNKVNLVKGVGTIVAPN 149
F GI+ + +T D K++ ++ G+ G + ++ L+KG VAP+
Sbjct: 65 FYDFGIDGADGLTIDHAAVMKRVRTFRDRFTSGVQAGSTDTLEADQ--LIKGYAKFVAPD 122
Query: 150 KVEVHGEKGVETVNTKNILIASGSE-VTPFPGVTFDEKQIITSTGALSLESVPKKMLVIG 208
VEV+G++ + I+IA+GS + P + ++K +ITS LE +PK++ VIG
Sbjct: 123 TVEVNGQQ----IQGDRIIIATGSRPIVPEEWRSLEDK-LITSDELFELERLPKRIAVIG 177
Query: 209 AGVIGLELGSVYQRLGADVTAIEFLTSIGGVGIDGEVAKTLQKILSKQGMKFKLGTKVLG 268
G+IGLE+G RLG +V E ++GG+ + ++ K++SK+ LG +
Sbjct: 178 LGIIGLEIGQALSRLGVEVIGFEMSNTLGGLQ-SPKASRQAIKLISKE-FPIYLG-EAAT 234
Query: 269 VKKEGSTIKVDVEAAKGGNKEVLDCDVVLISIGRRPYTKGLGLDKVGIALDDRGRIPVN- 327
V+ G +K+ V + G EV D V S+GRRP + L+K+G+ LD+ G P +
Sbjct: 235 VEPTGEGVKITVSS---GTFEV---DAVFASLGRRPNLDSIDLEKLGVELDETGMPPFDI 288
Query: 328 NKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYD-AIP-SVIYTSPE 385
+ Q ++ GDV + H+A EG + V P +Y P + + P+
Sbjct: 289 HTMQVANLPVFIAGDVNGFRPILHEAGHEGKIAVNNAMDYPEVTSYKRKTPLGIAFVDPQ 348
Query: 386 VGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGP 445
+G+ G E L + K N RA GE +G + + +DK + ++G ++ P
Sbjct: 349 IGFFGVGYESLDLDKTVVVDFKLE-RNNGRAIVMGEDKGVISLYADKASKQLIGGELMMP 407
Query: 446 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREA 484
+ A E ++ R+ + HP EA+ A
Sbjct: 408 HAEHFTHLLTWAVEQQLEVLELLRMPYYHPVLEEAIESA 446
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.316 0.137 0.391
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 550,937,239
Number of Sequences: 1657284
Number of extensions: 24195379
Number of successful extensions: 70198
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 1370
Number of HSP's successfully gapped in prelim test: 543
Number of HSP's that attempted gapping in prelim test: 65145
Number of HSP's gapped (non-prelim): 3452
length of query: 496
length of database: 575,637,011
effective HSP length: 104
effective length of query: 392
effective length of database: 403,279,475
effective search space: 158085554200
effective search space used: 158085554200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 74 (33.9 bits)
- SilkBase 1999-2023 -