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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000243-TA|BGIBMGA000243-PA|IPR013865|Protein of unknown
function DUF1754, eukaryotic
         (110 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC017286-1|AAH17286.1|  112|Homo sapiens family with sequence si...    94   1e-19
BC004447-1|AAH04447.1|   69|Homo sapiens FAM32A protein protein.       94   1e-19
BC000639-1|AAH00639.1|  112|Homo sapiens family with sequence si...    94   1e-19
AF151902-1|AAD34139.1|  112|Homo sapiens CGI-144 protein protein.      94   1e-19
BC093980-1|AAH93980.1|  404|Homo sapiens sorting nexin 5 protein.      29   2.3  
BC093623-1|AAH93623.1|  404|Homo sapiens sorting nexin 5 protein.      29   2.3  
BC062638-1|AAH62638.1|  412|Homo sapiens SNX5 protein protein.         29   2.3  
AL121585-2|CAC00471.1|  404|Homo sapiens sorting nexin 5 protein.      29   2.3  
AK223308-1|BAD97028.1|  404|Homo sapiens sorting nexin 5 variant...    29   2.3  
AK001793-1|BAA91914.1|  404|Homo sapiens protein ( Homo sapiens ...    29   2.3  
AF535142-1|AAN03486.1| 8749|Homo sapiens enaptin protein.              29   2.3  
AF495910-1|AAN60442.1| 8797|Homo sapiens nesprin-1 protein.            29   2.3  
AF121855-1|AAD27828.1|  404|Homo sapiens sorting nexin 5 protein.      29   2.3  
AK097519-1|BAC05086.1|  519|Homo sapiens protein ( Homo sapiens ...    29   3.1  
AY165122-1|AAO39147.1| 1995|Homo sapiens myosin heavy chain prot...    28   7.1  
M55542-1|AAA35871.1|  592|Homo sapiens guanylate binding protein...    27   9.4  
BT006847-1|AAP35493.1|  592|Homo sapiens guanylate binding prote...    27   9.4  
BC050326-1|AAH50326.1|  994|Homo sapiens NLR family, pyrin domai...    27   9.4  
BC002666-1|AAH02666.1|  592|Homo sapiens guanylate binding prote...    27   9.4  
AY920436-1|AAX13805.1|  592|Homo sapiens guanylate binding prote...    27   9.4  
AY072792-1|AAL68396.1|  994|Homo sapiens PAAD and NACHT-containi...    27   9.4  
AL160008-5|CAI22972.1|  592|Homo sapiens guanylate binding prote...    27   9.4  
AF479747-1|AAL87104.1|  994|Homo sapiens PYRIN-containing APAF1-...    27   9.4  
AF442488-1|AAL35293.1|  994|Homo sapiens NALP4 protein.                27   9.4  

>BC017286-1|AAH17286.1|  112|Homo sapiens family with sequence
           similarity 32, member A protein.
          Length = 112

 Score = 93.9 bits (223), Expect = 1e-19
 Identities = 40/58 (68%), Positives = 50/58 (86%)

Query: 53  VDRRTKAEIAYQNMQEKMQKQRILQKAEMTHKQRVEKFNQHLDSLTEHFDIPKVSWTK 110
           +D+RT A+ A++ MQEK Q +RIL+KA  THKQRVE FN+HLD+LTEH+DIPKVSWTK
Sbjct: 55  LDKRTPAQAAFEKMQEKRQMERILKKASKTHKQRVEDFNRHLDTLTEHYDIPKVSWTK 112


>BC004447-1|AAH04447.1|   69|Homo sapiens FAM32A protein protein.
          Length = 69

 Score = 93.9 bits (223), Expect = 1e-19
 Identities = 40/58 (68%), Positives = 50/58 (86%)

Query: 53  VDRRTKAEIAYQNMQEKMQKQRILQKAEMTHKQRVEKFNQHLDSLTEHFDIPKVSWTK 110
           +D+RT A+ A++ MQEK Q +RIL+KA  THKQRVE FN+HLD+LTEH+DIPKVSWTK
Sbjct: 12  LDKRTPAQAAFEKMQEKRQMERILKKASKTHKQRVEDFNRHLDTLTEHYDIPKVSWTK 69


>BC000639-1|AAH00639.1|  112|Homo sapiens family with sequence
           similarity 32, member A protein.
          Length = 112

 Score = 93.9 bits (223), Expect = 1e-19
 Identities = 40/58 (68%), Positives = 50/58 (86%)

Query: 53  VDRRTKAEIAYQNMQEKMQKQRILQKAEMTHKQRVEKFNQHLDSLTEHFDIPKVSWTK 110
           +D+RT A+ A++ MQEK Q +RIL+KA  THKQRVE FN+HLD+LTEH+DIPKVSWTK
Sbjct: 55  LDKRTPAQAAFEKMQEKRQMERILKKASKTHKQRVEDFNRHLDTLTEHYDIPKVSWTK 112


>AF151902-1|AAD34139.1|  112|Homo sapiens CGI-144 protein protein.
          Length = 112

 Score = 93.9 bits (223), Expect = 1e-19
 Identities = 40/58 (68%), Positives = 50/58 (86%)

Query: 53  VDRRTKAEIAYQNMQEKMQKQRILQKAEMTHKQRVEKFNQHLDSLTEHFDIPKVSWTK 110
           +D+RT A+ A++ MQEK Q +RIL+KA  THKQRVE FN+HLD+LTEH+DIPKVSWTK
Sbjct: 55  LDKRTPAQAAFEKMQEKRQMERILKKASKTHKQRVEDFNRHLDTLTEHYDIPKVSWTK 112


>BC093980-1|AAH93980.1|  404|Homo sapiens sorting nexin 5 protein.
          Length = 404

 Score = 29.5 bits (63), Expect = 2.3
 Identities = 18/49 (36%), Positives = 26/49 (53%), Gaps = 4/49 (8%)

Query: 55  RRTKAEIAYQNMQEKMQKQRILQK----AEMTHKQRVEKFNQHLDSLTE 99
           RRTKA I Y+N  + + K R+  K    AE   ++  +KF Q  +S  E
Sbjct: 311 RRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKE 359


>BC093623-1|AAH93623.1|  404|Homo sapiens sorting nexin 5 protein.
          Length = 404

 Score = 29.5 bits (63), Expect = 2.3
 Identities = 18/49 (36%), Positives = 26/49 (53%), Gaps = 4/49 (8%)

Query: 55  RRTKAEIAYQNMQEKMQKQRILQK----AEMTHKQRVEKFNQHLDSLTE 99
           RRTKA I Y+N  + + K R+  K    AE   ++  +KF Q  +S  E
Sbjct: 311 RRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKE 359


>BC062638-1|AAH62638.1|  412|Homo sapiens SNX5 protein protein.
          Length = 412

 Score = 29.5 bits (63), Expect = 2.3
 Identities = 18/49 (36%), Positives = 26/49 (53%), Gaps = 4/49 (8%)

Query: 55  RRTKAEIAYQNMQEKMQKQRILQK----AEMTHKQRVEKFNQHLDSLTE 99
           RRTKA I Y+N  + + K R+  K    AE   ++  +KF Q  +S  E
Sbjct: 319 RRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKE 367


>AL121585-2|CAC00471.1|  404|Homo sapiens sorting nexin 5 protein.
          Length = 404

 Score = 29.5 bits (63), Expect = 2.3
 Identities = 18/49 (36%), Positives = 26/49 (53%), Gaps = 4/49 (8%)

Query: 55  RRTKAEIAYQNMQEKMQKQRILQK----AEMTHKQRVEKFNQHLDSLTE 99
           RRTKA I Y+N  + + K R+  K    AE   ++  +KF Q  +S  E
Sbjct: 311 RRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKE 359


>AK223308-1|BAD97028.1|  404|Homo sapiens sorting nexin 5 variant
           protein.
          Length = 404

 Score = 29.5 bits (63), Expect = 2.3
 Identities = 18/49 (36%), Positives = 26/49 (53%), Gaps = 4/49 (8%)

Query: 55  RRTKAEIAYQNMQEKMQKQRILQK----AEMTHKQRVEKFNQHLDSLTE 99
           RRTKA I Y+N  + + K R+  K    AE   ++  +KF Q  +S  E
Sbjct: 311 RRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKE 359


>AK001793-1|BAA91914.1|  404|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10931 fis, clone OVARC1000564. ).
          Length = 404

 Score = 29.5 bits (63), Expect = 2.3
 Identities = 18/49 (36%), Positives = 26/49 (53%), Gaps = 4/49 (8%)

Query: 55  RRTKAEIAYQNMQEKMQKQRILQK----AEMTHKQRVEKFNQHLDSLTE 99
           RRTKA I Y+N  + + K R+  K    AE   ++  +KF Q  +S  E
Sbjct: 311 RRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKE 359


>AF535142-1|AAN03486.1| 8749|Homo sapiens enaptin protein.
          Length = 8749

 Score = 29.5 bits (63), Expect = 2.3
 Identities = 12/47 (25%), Positives = 26/47 (55%)

Query: 54   DRRTKAEIAYQNMQEKMQKQRILQKAEMTHKQRVEKFNQHLDSLTEH 100
            D++ +   + ++++E+  K+R+ +      +QR+  FNQ  D L  H
Sbjct: 1992 DQKEELLKSIEDIEERTDKERLKEPTRQALQQRLRVFNQLEDELNSH 2038


>AF495910-1|AAN60442.1| 8797|Homo sapiens nesprin-1 protein.
          Length = 8797

 Score = 29.5 bits (63), Expect = 2.3
 Identities = 12/47 (25%), Positives = 26/47 (55%)

Query: 54   DRRTKAEIAYQNMQEKMQKQRILQKAEMTHKQRVEKFNQHLDSLTEH 100
            D++ +   + ++++E+  K+R+ +      +QR+  FNQ  D L  H
Sbjct: 1985 DQKEELLKSIEDIEERTDKERLKEPTRQALQQRLRVFNQLEDELNSH 2031


>AF121855-1|AAD27828.1|  404|Homo sapiens sorting nexin 5 protein.
          Length = 404

 Score = 29.5 bits (63), Expect = 2.3
 Identities = 18/49 (36%), Positives = 26/49 (53%), Gaps = 4/49 (8%)

Query: 55  RRTKAEIAYQNMQEKMQKQRILQK----AEMTHKQRVEKFNQHLDSLTE 99
           RRTKA I Y+N  + + K R+  K    AE   ++  +KF Q  +S  E
Sbjct: 311 RRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKE 359


>AK097519-1|BAC05086.1|  519|Homo sapiens protein ( Homo sapiens
           cDNA FLJ40200 fis, clone TESTI2020071, weakly similar to
           Mus musculus epithelial protein lost in neoplasm-a
           (Eplin) mRNA. ).
          Length = 519

 Score = 29.1 bits (62), Expect = 3.1
 Identities = 12/48 (25%), Positives = 26/48 (54%)

Query: 58  KAEIAYQNMQEKMQKQRILQKAEMTHKQRVEKFNQHLDSLTEHFDIPK 105
           K  +   N   +  +  +L++  ++ ++R+E+F+  LD L   F+ PK
Sbjct: 78  KDSVDKSNNTREYGRPEVLKEDSLSSRRRIERFSIALDELRSVFEAPK 125


>AY165122-1|AAO39147.1| 1995|Homo sapiens myosin heavy chain protein.
          Length = 1995

 Score = 27.9 bits (59), Expect = 7.1
 Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 1/42 (2%)

Query: 55   RRTKAEIAY-QNMQEKMQKQRILQKAEMTHKQRVEKFNQHLD 95
            RR++A I+Y  NM+ + Q  R   + E   +Q +EK  + LD
Sbjct: 1037 RRSRASISYGSNMRPQSQTWRDRLRKEEKGRQELEKLKRRLD 1078


>M55542-1|AAA35871.1|  592|Homo sapiens guanylate binding protein
           isoform I protein.
          Length = 592

 Score = 27.5 bits (58), Expect = 9.4
 Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 3/55 (5%)

Query: 56  RTKAEIAYQNMQEKMQKQRILQKAEMTHKQRVEKFNQHLDSLTEHFDIPKVSWTK 110
           R KAE A  + +   + QR   K E   +Q+   + +HL  LTE  +  +V   K
Sbjct: 493 RVKAESAQASAKMLQEMQR---KNEQMMEQKERSYQEHLKQLTEKMENDRVQLLK 544


>BT006847-1|AAP35493.1|  592|Homo sapiens guanylate binding protein
           1, interferon-inducible, 67kDa protein.
          Length = 592

 Score = 27.5 bits (58), Expect = 9.4
 Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 3/55 (5%)

Query: 56  RTKAEIAYQNMQEKMQKQRILQKAEMTHKQRVEKFNQHLDSLTEHFDIPKVSWTK 110
           R KAE A  + +   + QR   K E   +Q+   + +HL  LTE  +  +V   K
Sbjct: 493 RVKAESAQASAKMLQEMQR---KNEQMMEQKERSYQEHLKQLTEKMENDRVQLLK 544


>BC050326-1|AAH50326.1|  994|Homo sapiens NLR family, pyrin domain
           containing 4 protein.
          Length = 994

 Score = 27.5 bits (58), Expect = 9.4
 Identities = 9/31 (29%), Positives = 17/31 (54%)

Query: 80  EMTHKQRVEKFNQHLDSLTEHFDIPKVSWTK 110
           E   K+   KF +HL  +T   ++ ++ WT+
Sbjct: 16  EELKKEEFRKFKEHLKQMTLQLELKQIPWTE 46


>BC002666-1|AAH02666.1|  592|Homo sapiens guanylate binding protein
           1, interferon-inducible, 67kDa protein.
          Length = 592

 Score = 27.5 bits (58), Expect = 9.4
 Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 3/55 (5%)

Query: 56  RTKAEIAYQNMQEKMQKQRILQKAEMTHKQRVEKFNQHLDSLTEHFDIPKVSWTK 110
           R KAE A  + +   + QR   K E   +Q+   + +HL  LTE  +  +V   K
Sbjct: 493 RVKAESAQASAKMLQEMQR---KNEQMMEQKERSYQEHLKQLTEKMENDRVQLLK 544


>AY920436-1|AAX13805.1|  592|Homo sapiens guanylate binding protein
           1 protein.
          Length = 592

 Score = 27.5 bits (58), Expect = 9.4
 Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 3/55 (5%)

Query: 56  RTKAEIAYQNMQEKMQKQRILQKAEMTHKQRVEKFNQHLDSLTEHFDIPKVSWTK 110
           R KAE A  + +   + QR   K E   +Q+   + +HL  LTE  +  +V   K
Sbjct: 493 RVKAESAQASAKMLQEMQR---KNEQMMEQKERSYQEHLKQLTEKMENDRVQLLK 544


>AY072792-1|AAL68396.1|  994|Homo sapiens PAAD and NACHT-containing
           protein 2 protein.
          Length = 994

 Score = 27.5 bits (58), Expect = 9.4
 Identities = 9/31 (29%), Positives = 17/31 (54%)

Query: 80  EMTHKQRVEKFNQHLDSLTEHFDIPKVSWTK 110
           E   K+   KF +HL  +T   ++ ++ WT+
Sbjct: 16  EELKKEEFRKFKEHLKQMTLQLELKQIPWTE 46


>AL160008-5|CAI22972.1|  592|Homo sapiens guanylate binding protein
           1, interferon-inducible, 67kDa protein.
          Length = 592

 Score = 27.5 bits (58), Expect = 9.4
 Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 3/55 (5%)

Query: 56  RTKAEIAYQNMQEKMQKQRILQKAEMTHKQRVEKFNQHLDSLTEHFDIPKVSWTK 110
           R KAE A  + +   + QR   K E   +Q+   + +HL  LTE  +  +V   K
Sbjct: 493 RVKAESAQASAKMLQEMQR---KNEQMMEQKERSYQEHLKQLTEKMENDRVQLLK 544


>AF479747-1|AAL87104.1|  994|Homo sapiens PYRIN-containing
           APAF1-like protein 4 protein.
          Length = 994

 Score = 27.5 bits (58), Expect = 9.4
 Identities = 9/31 (29%), Positives = 17/31 (54%)

Query: 80  EMTHKQRVEKFNQHLDSLTEHFDIPKVSWTK 110
           E   K+   KF +HL  +T   ++ ++ WT+
Sbjct: 16  EELKKEEFRKFKEHLKQMTLQLELKQIPWTE 46


>AF442488-1|AAL35293.1|  994|Homo sapiens NALP4 protein.
          Length = 994

 Score = 27.5 bits (58), Expect = 9.4
 Identities = 9/31 (29%), Positives = 17/31 (54%)

Query: 80  EMTHKQRVEKFNQHLDSLTEHFDIPKVSWTK 110
           E   K+   KF +HL  +T   ++ ++ WT+
Sbjct: 16  EELKKEEFRKFKEHLKQMTLQLELKQIPWTE 46


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.314    0.126    0.363 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 10,106,247
Number of Sequences: 224733
Number of extensions: 231545
Number of successful extensions: 1456
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1439
Number of HSP's gapped (non-prelim): 30
length of query: 110
length of database: 73,234,838
effective HSP length: 79
effective length of query: 31
effective length of database: 55,480,931
effective search space: 1719908861
effective search space used: 1719908861
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 58 (27.5 bits)

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