Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000241-TA|BGIBMGA000241-PA|IPR008973|C2
calcium/lipid-binding region, CaLB
(986 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AY254099-1|AAP80572.1| 2030|Homo sapiens DOCK3 protein. 507 e-143
AY145303-1|AAN12301.1| 2030|Homo sapiens modifier of cell adhesi... 507 e-143
AB002297-1|BAA20759.1| 1907|Homo sapiens KIAA0299 protein. 507 e-143
BC117694-1|AAI17695.1| 1106|Homo sapiens DOCK4 protein protein. 489 e-137
BC117688-1|AAI17689.1| 1966|Homo sapiens dedicator of cytokinesi... 489 e-137
AY233380-1|AAO73565.1| 1966|Homo sapiens DOCK4 protein. 489 e-137
BC117689-1|AAI17690.1| 2011|Homo sapiens DOCK4 protein protein. 427 e-118
D50857-1|BAA09454.1| 1865|Homo sapiens DOCK180 protein protein. 353 1e-96
BX470201-1|CAH72560.2| 1865|Homo sapiens dedicator of cytokinesi... 353 1e-96
BX470155-1|CAI22477.2| 1865|Homo sapiens dedicator of cytokinesi... 353 1e-96
AL607029-1|CAI15329.2| 1865|Homo sapiens dedicator of cytokinesi... 353 1e-96
AL390920-1|CAH73231.2| 1865|Homo sapiens dedicator of cytokinesi... 353 1e-96
AL359094-1|CAH71477.2| 1865|Homo sapiens dedicator of cytokinesi... 353 1e-96
AL355316-1|CAI16871.2| 1865|Homo sapiens dedicator of cytokinesi... 353 1e-96
AL157711-1|CAH71463.2| 1865|Homo sapiens dedicator of cytokinesi... 353 1e-96
D86964-1|BAA13200.1| 1842|Homo sapiens KIAA0209 protein. 331 6e-90
BC113457-1|AAI13458.1| 1830|Homo sapiens dedicator of cytokinesi... 331 6e-90
BC104900-1|AAI04901.1| 1830|Homo sapiens dedicator of cytokinesi... 331 6e-90
AB018259-1|BAA34436.3| 1388|Homo sapiens KIAA0716 protein protein. 247 2e-64
AK123607-1|BAC85660.1| 677|Homo sapiens protein ( Homo sapiens ... 197 2e-49
AK091557-1|BAC03696.1| 775|Homo sapiens protein ( Homo sapiens ... 155 7e-37
BC016996-1|AAH16996.1| 336|Homo sapiens DOCK2 protein protein. 98 2e-19
AK126249-1|BAC86503.1| 942|Homo sapiens protein ( Homo sapiens ... 79 1e-13
BC084559-1|AAH84559.1| 152|Homo sapiens DOCK1 protein protein. 70 4e-11
AC003077-1|AAB83946.1| 843|Homo sapiens WUGSC:H_GS034D21.1 prot... 64 3e-09
DQ341187-1|ABC68221.1| 2129|Homo sapiens dedicator of cytokinesi... 43 0.005
DQ309763-1|ABC33725.1| 803|Homo sapiens dedicator of cytokinesi... 43 0.005
DQ118680-1|AAZ38452.1| 1990|Homo sapiens dedicator of cytokinesi... 43 0.005
DQ118679-1|AAZ38451.1| 1992|Homo sapiens dedicator of cytokinesi... 43 0.005
AL451044-1|CAI13104.1| 2109|Homo sapiens dedicator of cytokinesi... 43 0.005
AL138847-2|CAI22995.1| 2109|Homo sapiens dedicator of cytokinesi... 43 0.005
AK125049-1|BAC86032.1| 1520|Homo sapiens protein ( Homo sapiens ... 38 0.23
BC130518-1|AAI30519.1| 1999|Homo sapiens DOCK8 protein protein. 37 0.41
AL161725-3|CAM13234.1| 2031|Homo sapiens dedicator of cytokinesi... 37 0.41
AL158832-3|CAM22536.1| 2031|Homo sapiens dedicator of cytokinesi... 37 0.41
AK090429-1|BAC03410.1| 1799|Homo sapiens FLJ00346 protein protein. 37 0.41
AB191037-1|BAE45254.1| 2099|Homo sapiens dedicator of cytokinesi... 37 0.41
AY692226-1|AAU04438.1| 2073|Homo sapiens Cdc42-associated guanin... 36 0.71
AL391280-3|CAI41411.1| 2077|Homo sapiens dedicator of cytokinesi... 35 1.2
AL391237-2|CAI41407.1| 2077|Homo sapiens dedicator of cytokinesi... 35 1.2
AL161725-1|CAM13232.1| 1566|Homo sapiens dedicator of cytokinesi... 33 5.0
AK074081-1|BAB84907.1| 1373|Homo sapiens FLJ00152 protein protein. 33 5.0
BC131527-1|AAI31528.1| 823|Homo sapiens MCTP2 protein protein. 33 6.6
BC011877-1|AAH11877.1| 350|Homo sapiens DOCK5 protein protein. 33 6.6
AY656717-1|AAT73060.1| 878|Homo sapiens MCTP2 protein. 33 6.6
>AY254099-1|AAP80572.1| 2030|Homo sapiens DOCK3 protein.
Length = 2030
Score = 507 bits (1250), Expect = e-143
Identities = 317/937 (33%), Positives = 495/937 (52%), Gaps = 83/937 (8%)
Query: 66 LGLELVPRRGAEAVEPEDISLVELYRVHVESAERAAAVRLRFYNFIIDIXXXXXXXXXXX 125
LGL+LVPR+ E V+ + IS+ +LY++H+ S + +
Sbjct: 157 LGLDLVPRKDFEVVDSDQISVSDLYKMHLSSRQS------------VQQSTSQVDTMRPR 204
Query: 126 XXXXXXXXQSHHLMCSMRDFGHTAGGDEAELLLWLHDARRSQPLSERFRIRIARDGFSNY 185
HH S++ F + G++ ++ L+D R + +SERF +R+ ++G
Sbjct: 205 HGETCRMPVPHHFFLSLKSFTYNTIGEDTDVFFSLYDMREGKQISERFLVRLNKNGGPRN 264
Query: 186 ------------DLSTTDLTRELWLVAWVIRVXXXXXXXXXXXXXXXXXXPVARRPLGAG 233
DLS+ D+ R+L++VA VIR+ RRP G
Sbjct: 265 PEKIERMCALFTDLSSKDMKRDLYIVAHVIRIGRMLLNDSKKGPPHLHY----RRPYGCA 320
Query: 234 VLSLADFLRQTGQHPAEKEYTFKVYQCE-EKEFHQLHDMLIRKQTNKCNILPGQPNYGIV 292
VLS+ D L+ + EK++ KVY C E E+ Q+H+ +IRK + K + ++G++
Sbjct: 321 VLSILDVLQSLTEVKEEKDFVLKVYTCNNESEWSQIHENIIRKSSAKYSA--PSASHGLI 378
Query: 293 VALRLLANSGSVTEA-----VASGATITAKRGFPDVIMPGDVRNDLYLTLEKAEFERGGK 347
++L+LL G IT K GFPDVIMPGD+RNDLYLTLEK +FERGGK
Sbjct: 379 ISLQLLRGDMEQIRRENPMIFNRGLAITRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGK 438
Query: 348 STAKNVLATVTVHDNTGQVISDCVWGASGNGS-TSYESLVLYHNNSPAWGEQLRLTVPLE 406
S KN+ T+ V G+++ DC+ SG + +SY S VLYH+NSP WGE ++L +P++
Sbjct: 439 SVQKNIEVTMYVLYADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWGEIIKLPIPID 498
Query: 407 TFTHAHVRIEFRHCSTRDKNERKLFGFAFARLMEASGATLRDGAHELHVYKCDDPSKLLT 466
F +H+R EFRHCST+DK E+KLFGFAF+ LM G TL D HEL+VYKCD+ S
Sbjct: 499 RFRGSHLRFEFRHCSTKDKGEKKLFGFAFSTLMRDDGTTLSDDIHELYVYKCDENSTFNN 558
Query: 467 -ASYLSLPSCANDAARAAP--PNGVVPSFQRSSKENCTISTLLCSTKLTQNEDLLALLQW 523
A YL LP C D P P+ ++ FQRS+KE+ IST L STKLTQN DLLALL+W
Sbjct: 559 HALYLGLPCCKED-YNGCPNIPSSLI--FQRSTKESFFISTQLSSTKLTQNVDLLALLKW 615
Query: 524 RAHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFSTEDGNSTPHSGTVFLVLI 583
+A P+++ + L R+ +S EE++KFL+D+LD LF + D N+ + VF L+
Sbjct: 616 KAFPDRIMDVLGRLRH----VSGEEIVKFLQDILDTLFVIL---DDNTEKYGLLVFQSLV 668
Query: 584 SICSLLDESRFQHFKPVLDVYIEEHFSAALVYKGLLSSVQHCAEWAAGAEGQEPIRKCLR 643
I +LL + ++ HF+PV+D YI++HF+ AL YK L+ ++ + +A Q+ I++ +R
Sbjct: 669 FIINLLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDCSAELIRQDHIQEAMR 728
Query: 644 SLGAVFRLAVQSRRLFARATGGQYEDSFRRDVRAALHALKAFAQHPHR--EHLAPAQIAL 701
+L +F+ VQSR L++RAT G E+ FR ++ +++ R E L Q AL
Sbjct: 729 ALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRNSETLLFTQAAL 788
Query: 702 MTSWASVAREVSAALGAAETA---RVSAAVLDAPVSXXXXXXXXXXXXXXXXXXGPLGED 758
+ S+ ++ E+ E A R + + + V L
Sbjct: 789 LNSFPTIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSF 848
Query: 759 PEARNIILTTACHHLRVHLARRDELFQCAEMLGELVTLLWKKRXXXXXXXXXXXXXXXXX 818
E+R I+L HH+ +HL ++ EL C+ +LG + +++
Sbjct: 849 SESRRILLPVVLHHIHLHLRQQKELLICSGILGSIFSIV------KTSSLEADVMEEVEM 902
Query: 819 XCLNTLDVLVETVLHLI----------GGNSP-----VLGSMVAALLGVMELLRPIHYQR 863
+ LDVL++T+L ++ G P + G V+ LL ++ + H+Q
Sbjct: 903 MVESLLDVLLQTLLTIMSKSHAQEAVRGQRCPQCTAEITGEYVSCLLSLLRQMCDTHFQ- 961
Query: 864 LWSHLAPHPHDRKPLKDFLMRAFLVFRHLIEQDVFPPDWMVLRVQSCKVLLSALQDLAEP 923
HL + + LK+FL++ F VFR+L++ VFP DWMV+R+ + ++++ +Q L+
Sbjct: 962 ---HLLDNFQSKDELKEFLLKIFCVFRNLMKMSVFPRDWMVMRLLTSNIIVTTVQYLSSA 1018
Query: 924 LLERFLGEEPPQFDTQLWSGYMELGVSLVTAGALQTE 960
L + F + FD ++W+ Y L V + +LQ E
Sbjct: 1019 LHKNFTETD---FDFKVWNSYFSLAVLFINQPSLQLE 1052
>AY145303-1|AAN12301.1| 2030|Homo sapiens modifier of cell adhesion
protein.
Length = 2030
Score = 507 bits (1250), Expect = e-143
Identities = 317/937 (33%), Positives = 495/937 (52%), Gaps = 83/937 (8%)
Query: 66 LGLELVPRRGAEAVEPEDISLVELYRVHVESAERAAAVRLRFYNFIIDIXXXXXXXXXXX 125
LGL+LVPR+ E V+ + IS+ +LY++H+ S + +
Sbjct: 157 LGLDLVPRKDFEVVDSDQISVSDLYKMHLSSRQS------------VQQSTSQVDTMRPR 204
Query: 126 XXXXXXXXQSHHLMCSMRDFGHTAGGDEAELLLWLHDARRSQPLSERFRIRIARDGFSNY 185
HH S++ F + G++ ++ L+D R + +SERF +R+ ++G
Sbjct: 205 HGETCRMPVPHHFFLSLKSFTYNTIGEDTDVFFSLYDMREGKQISERFLVRLNKNGGPRN 264
Query: 186 ------------DLSTTDLTRELWLVAWVIRVXXXXXXXXXXXXXXXXXXPVARRPLGAG 233
DLS+ D+ R+L++VA VIR+ RRP G
Sbjct: 265 PEKIERMCALFTDLSSKDMKRDLYIVAHVIRIGRMLLNDSKKGPPHLHY----RRPYGCA 320
Query: 234 VLSLADFLRQTGQHPAEKEYTFKVYQCE-EKEFHQLHDMLIRKQTNKCNILPGQPNYGIV 292
VLS+ D L+ + EK++ KVY C E E+ Q+H+ +IRK + K + ++G++
Sbjct: 321 VLSILDVLQSLTEVKEEKDFVLKVYTCNNESEWSQIHENIIRKSSAKYSA--PSASHGLI 378
Query: 293 VALRLLANSGSVTEA-----VASGATITAKRGFPDVIMPGDVRNDLYLTLEKAEFERGGK 347
++L+LL G IT K GFPDVIMPGD+RNDLYLTLEK +FERGGK
Sbjct: 379 ISLQLLRGDMEQIRRENPMIFNRGLAITRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGK 438
Query: 348 STAKNVLATVTVHDNTGQVISDCVWGASGNGS-TSYESLVLYHNNSPAWGEQLRLTVPLE 406
S KN+ T+ V G+++ DC+ SG + +SY S VLYH+NSP WGE ++L +P++
Sbjct: 439 SVQKNIEVTMYVLYADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWGEIIKLPIPID 498
Query: 407 TFTHAHVRIEFRHCSTRDKNERKLFGFAFARLMEASGATLRDGAHELHVYKCDDPSKLLT 466
F +H+R EFRHCST+DK E+KLFGFAF+ LM G TL D HEL+VYKCD+ S
Sbjct: 499 RFRGSHLRFEFRHCSTKDKGEKKLFGFAFSTLMRDDGTTLSDDIHELYVYKCDENSTFNN 558
Query: 467 -ASYLSLPSCANDAARAAP--PNGVVPSFQRSSKENCTISTLLCSTKLTQNEDLLALLQW 523
A YL LP C D P P+ ++ FQRS+KE+ IST L STKLTQN DLLALL+W
Sbjct: 559 HALYLGLPCCKED-YNGCPNIPSSLI--FQRSTKESFFISTQLSSTKLTQNVDLLALLKW 615
Query: 524 RAHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFSTEDGNSTPHSGTVFLVLI 583
+A P+++ + L R+ +S EE++KFL+D+LD LF + D N+ + VF L+
Sbjct: 616 KAFPDRIMDVLGRLRH----VSGEEIVKFLQDILDTLFVIL---DDNTEKYGLLVFQSLV 668
Query: 584 SICSLLDESRFQHFKPVLDVYIEEHFSAALVYKGLLSSVQHCAEWAAGAEGQEPIRKCLR 643
I +LL + ++ HF+PV+D YI++HF+ AL YK L+ ++ + +A Q+ I++ +R
Sbjct: 669 FIINLLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDCSAELIRQDHIQEAMR 728
Query: 644 SLGAVFRLAVQSRRLFARATGGQYEDSFRRDVRAALHALKAFAQHPHR--EHLAPAQIAL 701
+L +F+ VQSR L++RAT G E+ FR ++ +++ R E L Q AL
Sbjct: 729 ALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRNSETLLFTQAAL 788
Query: 702 MTSWASVAREVSAALGAAETA---RVSAAVLDAPVSXXXXXXXXXXXXXXXXXXGPLGED 758
+ S+ ++ E+ E A R + + + V L
Sbjct: 789 LNSFPTIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSF 848
Query: 759 PEARNIILTTACHHLRVHLARRDELFQCAEMLGELVTLLWKKRXXXXXXXXXXXXXXXXX 818
E+R I+L HH+ +HL ++ EL C+ +LG + +++
Sbjct: 849 SESRRILLPVVLHHIHLHLRQQKELLICSGILGSIFSIV------KTSSLEADVMEEVEM 902
Query: 819 XCLNTLDVLVETVLHLI----------GGNSP-----VLGSMVAALLGVMELLRPIHYQR 863
+ LDVL++T+L ++ G P + G V+ LL ++ + H+Q
Sbjct: 903 MVESLLDVLLQTLLTIMSKSHAQEAVRGQRCPQCTAEITGEYVSCLLSLLRQMCDTHFQ- 961
Query: 864 LWSHLAPHPHDRKPLKDFLMRAFLVFRHLIEQDVFPPDWMVLRVQSCKVLLSALQDLAEP 923
HL + + LK+FL++ F VFR+L++ VFP DWMV+R+ + ++++ +Q L+
Sbjct: 962 ---HLLDNFQSKDELKEFLLKIFCVFRNLMKMSVFPRDWMVMRLLTSNIIVTTVQYLSSA 1018
Query: 924 LLERFLGEEPPQFDTQLWSGYMELGVSLVTAGALQTE 960
L + F + FD ++W+ Y L V + +LQ E
Sbjct: 1019 LHKNFTETD---FDFKVWNSYFSLAVLFINQPSLQLE 1052
>AB002297-1|BAA20759.1| 1907|Homo sapiens KIAA0299 protein.
Length = 1907
Score = 507 bits (1250), Expect = e-143
Identities = 317/937 (33%), Positives = 495/937 (52%), Gaps = 83/937 (8%)
Query: 66 LGLELVPRRGAEAVEPEDISLVELYRVHVESAERAAAVRLRFYNFIIDIXXXXXXXXXXX 125
LGL+LVPR+ E V+ + IS+ +LY++H+ S + +
Sbjct: 34 LGLDLVPRKDFEVVDSDQISVSDLYKMHLSSRQS------------VQQSTSQVDTMRPR 81
Query: 126 XXXXXXXXQSHHLMCSMRDFGHTAGGDEAELLLWLHDARRSQPLSERFRIRIARDGFSNY 185
HH S++ F + G++ ++ L+D R + +SERF +R+ ++G
Sbjct: 82 HGETCRMPVPHHFFLSLKSFTYNTIGEDTDVFFSLYDMREGKQISERFLVRLNKNGGPRN 141
Query: 186 ------------DLSTTDLTRELWLVAWVIRVXXXXXXXXXXXXXXXXXXPVARRPLGAG 233
DLS+ D+ R+L++VA VIR+ RRP G
Sbjct: 142 PEKIERMCALFTDLSSKDMKRDLYIVAHVIRIGRMLLNDSKKGPPHLHY----RRPYGCA 197
Query: 234 VLSLADFLRQTGQHPAEKEYTFKVYQCE-EKEFHQLHDMLIRKQTNKCNILPGQPNYGIV 292
VLS+ D L+ + EK++ KVY C E E+ Q+H+ +IRK + K + ++G++
Sbjct: 198 VLSILDVLQSLTEVKEEKDFVLKVYTCNNESEWSQIHENIIRKSSAKYSA--PSASHGLI 255
Query: 293 VALRLLANSGSVTEA-----VASGATITAKRGFPDVIMPGDVRNDLYLTLEKAEFERGGK 347
++L+LL G IT K GFPDVIMPGD+RNDLYLTLEK +FERGGK
Sbjct: 256 ISLQLLRGDMEQIRRENPMIFNRGLAITRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGK 315
Query: 348 STAKNVLATVTVHDNTGQVISDCVWGASGNGS-TSYESLVLYHNNSPAWGEQLRLTVPLE 406
S KN+ T+ V G+++ DC+ SG + +SY S VLYH+NSP WGE ++L +P++
Sbjct: 316 SVQKNIEVTMYVLYADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWGEIIKLPIPID 375
Query: 407 TFTHAHVRIEFRHCSTRDKNERKLFGFAFARLMEASGATLRDGAHELHVYKCDDPSKLLT 466
F +H+R EFRHCST+DK E+KLFGFAF+ LM G TL D HEL+VYKCD+ S
Sbjct: 376 RFRGSHLRFEFRHCSTKDKGEKKLFGFAFSTLMRDDGTTLSDDIHELYVYKCDENSTFNN 435
Query: 467 -ASYLSLPSCANDAARAAP--PNGVVPSFQRSSKENCTISTLLCSTKLTQNEDLLALLQW 523
A YL LP C D P P+ ++ FQRS+KE+ IST L STKLTQN DLLALL+W
Sbjct: 436 HALYLGLPCCKED-YNGCPNIPSSLI--FQRSTKESFFISTQLSSTKLTQNVDLLALLKW 492
Query: 524 RAHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFSTEDGNSTPHSGTVFLVLI 583
+A P+++ + L R+ +S EE++KFL+D+LD LF + D N+ + VF L+
Sbjct: 493 KAFPDRIMDVLGRLRH----VSGEEIVKFLQDILDTLFVIL---DDNTEKYGLLVFQSLV 545
Query: 584 SICSLLDESRFQHFKPVLDVYIEEHFSAALVYKGLLSSVQHCAEWAAGAEGQEPIRKCLR 643
I +LL + ++ HF+PV+D YI++HF+ AL YK L+ ++ + +A Q+ I++ +R
Sbjct: 546 FIINLLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDCSAELIRQDHIQEAMR 605
Query: 644 SLGAVFRLAVQSRRLFARATGGQYEDSFRRDVRAALHALKAFAQHPHR--EHLAPAQIAL 701
+L +F+ VQSR L++RAT G E+ FR ++ +++ R E L Q AL
Sbjct: 606 ALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRNSETLLFTQAAL 665
Query: 702 MTSWASVAREVSAALGAAETA---RVSAAVLDAPVSXXXXXXXXXXXXXXXXXXGPLGED 758
+ S+ ++ E+ E A R + + + V L
Sbjct: 666 LNSFPTIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSF 725
Query: 759 PEARNIILTTACHHLRVHLARRDELFQCAEMLGELVTLLWKKRXXXXXXXXXXXXXXXXX 818
E+R I+L HH+ +HL ++ EL C+ +LG + +++
Sbjct: 726 SESRRILLPVVLHHIHLHLRQQKELLICSGILGSIFSIV------KTSSLEADVMEEVEM 779
Query: 819 XCLNTLDVLVETVLHLI----------GGNSP-----VLGSMVAALLGVMELLRPIHYQR 863
+ LDVL++T+L ++ G P + G V+ LL ++ + H+Q
Sbjct: 780 MVESLLDVLLQTLLTIMSKSHAQEAVRGQRCPQCTAEITGEYVSCLLSLLRQMCDTHFQ- 838
Query: 864 LWSHLAPHPHDRKPLKDFLMRAFLVFRHLIEQDVFPPDWMVLRVQSCKVLLSALQDLAEP 923
HL + + LK+FL++ F VFR+L++ VFP DWMV+R+ + ++++ +Q L+
Sbjct: 839 ---HLLDNFQSKDELKEFLLKIFCVFRNLMKMSVFPRDWMVMRLLTSNIIVTTVQYLSSA 895
Query: 924 LLERFLGEEPPQFDTQLWSGYMELGVSLVTAGALQTE 960
L + F + FD ++W+ Y L V + +LQ E
Sbjct: 896 LHKNFTETD---FDFKVWNSYFSLAVLFINQPSLQLE 929
>BC117694-1|AAI17695.1| 1106|Homo sapiens DOCK4 protein protein.
Length = 1106
Score = 489 bits (1205), Expect = e-137
Identities = 318/942 (33%), Positives = 490/942 (52%), Gaps = 101/942 (10%)
Query: 65 KLGLELVPRRGAEAVEPEDISLVELYRVHVESAERAAAVRLRFYNFIIDIXXXXXXXXXX 124
+LGL+LVPR+ V+PEDIS+ ELYR+ +E R ++
Sbjct: 156 QLGLDLVPRKEYAMVDPEDISITELYRL-MEHRHRKKDTPVQ------------------ 196
Query: 125 XXXXXXXXXQSHHLMCSMRDFGHTAGGDEAELLLWLHDARRSQPLSERFRIRIARDGFSN 184
Q LMCS G+E E++ L D++ ++P+SERF +R+ R+G
Sbjct: 197 -ASSHHLFVQMKSLMCSNL-------GEELEVIFSLFDSKENRPISERFFLRLNRNGLPK 248
Query: 185 ------------YDLSTTDLTRELWLVAWVIRVXXXXXXXXXXXXXXXXXXPVARRPLGA 232
DL +++L +++++ +IR+ RRP G
Sbjct: 249 APDKPERHCSLFVDLGSSELRKDIYITVHIIRIGRMGAGEKKNACSVQY-----RRPFGC 303
Query: 233 GVLSLADFLRQTGQHPAEKEYTFKVYQCE-EKEFHQLHDMLIRKQTNKCNILPGQPNYGI 291
VLS+AD L TG+ + + KVY C E E++Q+H+ +I+K + N L G N G+
Sbjct: 304 AVLSIADLL--TGE--TKDDLILKVYMCNTESEWYQIHENIIKKLNARYN-LTGS-NAGL 357
Query: 292 VVALRLLANS-----GSVTEAVASGATITAKRGFPDVIMPGDVRNDLYLTLEKAEFERGG 346
V+L+LL + + G +IT K GF ++IMPG++RNDLY+T+E+ EFE+GG
Sbjct: 358 AVSLQLLHGDIEQIRREYSSVFSHGVSITRKLGFSNIIMPGEMRNDLYITIERGEFEKGG 417
Query: 347 KSTAKNVLATVTVHDNTGQVISDCVWGASGNGSTS-YESLVLYHNNSPAWGEQLRLTVPL 405
KS A+NV T+ + D++GQ + D + SG S Y S VLYHNNSP W E L+L +P+
Sbjct: 418 KSVARNVEVTMFIVDSSGQTLKDFISFGSGEPPASEYHSFVLYHNNSPRWSELLKLPIPV 477
Query: 406 ETFTHAHVRIEFRHCSTRDKNERKLFGFAFARLMEASGATLRDGAHELHVYKCDDPSKLL 465
+ F AH+R EFRHCST++K E+KLFGF+F LM+ G TL DG HEL V+KC++ + L
Sbjct: 478 DKFRGAHIRFEFRHCSTKEKGEKKLFGFSFVPLMQEDGRTLPDGTHELIVHKCEENTNLQ 537
Query: 466 -TASYLSLPSCANDAARAAPPNGVVPSFQRSSKENCTISTLLCSTKLTQNEDLLALLQWR 524
T YL LP G +++KE+ I++ LCSTKLTQN D+L LL+WR
Sbjct: 538 DTTRYLKLPFSKGIFL------GNNNQAMKATKESFCITSFLCSTKLTQNGDMLDLLKWR 591
Query: 525 AHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFSTEDGNSTPHSGTVFLVLIS 584
HP+K+ L ++ + DG E++KFL+D LD LF + D NS + VF L+
Sbjct: 592 THPDKITGCLSKLKEI-DG---SEIVKFLQDTLDTLFGIL---DENSQKYGSKVFDSLVH 644
Query: 585 ICSLLDESRFQHFKPVLDVYIEEHFSAALVYKGLLSSVQHCAEWAAGAEGQEPIRKCLRS 644
I +LL +S+F HFKPV+D YIE HF+ AL Y+ L+ ++ + AE QE I++ L++
Sbjct: 645 IINLLQDSKFHHFKPVMDTYIESHFAGALAYRDLIKVLKWYVDRITEAERQEHIQEVLKA 704
Query: 645 LGAVFRLAVQSRRLFARATGGQYEDSFRRDVRAALHALKAFAQHPHREH--LAPAQIALM 702
+F+ VQSRRLF+ ATGGQ E+ FR ++ L +++ F + L+ +Q +
Sbjct: 705 QEYIFKYIVQSRRLFSLATGGQNEEEFRCCIQELLMSVRFFLSQESKGSGALSQSQAVFL 764
Query: 703 TSWASVAREVSAALGAAETARV---SAAVLDAPVSXXXXXXXXXXXXXXXXXXGPLGEDP 759
+S+ +V E+ E A + + L + L +P
Sbjct: 765 SSFPAVYSELLKLFDVREVANLVQDTLGSLPTILHVDDSLQAIKLQCIGKTVESQLYTNP 824
Query: 760 EARNIILTTACHHLRVHLARRDELFQCAEMLGELVTLLWKKRXXXXXXXXXXXXXXXXXX 819
++R I+L HHL +HL + +L CA +L + L+ K
Sbjct: 825 DSRYILLPVVLHHLHIHLQEQKDLIMCARILSNVFCLIKKN------SSEKSVLEEIDVI 878
Query: 820 CLNTLDVLVETVLHLIGGNSP-----------VLGSMVAALLGVMELLRPIHYQRLWSHL 868
+ LD+L+ T+L + P V G VA LL ++ + HYQ+L
Sbjct: 879 VASLLDILLRTILEITSRPQPSSSAMRFQFQDVTGEFVACLLSLLRQMTDRHYQQLLDSF 938
Query: 869 APHPHDRKPLKDFLMRAFLVFRHLIEQDVFPPDWMVLRVQSCKVLLSALQDLAEPLLERF 928
+ ++ L+DFL++ F VFR LI ++FP DW V+R+ + V+++ + L++ L + F
Sbjct: 939 ----NTKEELRDFLLQIFTVFRILIRPEMFPKDWTVMRLVANNVIITTVLYLSDALRKNF 994
Query: 929 LGEEPPQFDTQLWSGYMELGVSLVTAGALQTERWHTPRMRAR 970
L E FD ++W Y L V + LQ E + TP + +
Sbjct: 995 LNE---NFDYKIWDSYFYLAVIFINQLCLQLEMF-TPSKKKK 1032
>BC117688-1|AAI17689.1| 1966|Homo sapiens dedicator of cytokinesis 4
protein.
Length = 1966
Score = 489 bits (1205), Expect = e-137
Identities = 318/942 (33%), Positives = 490/942 (52%), Gaps = 101/942 (10%)
Query: 65 KLGLELVPRRGAEAVEPEDISLVELYRVHVESAERAAAVRLRFYNFIIDIXXXXXXXXXX 124
+LGL+LVPR+ V+PEDIS+ ELYR+ +E R ++
Sbjct: 156 QLGLDLVPRKEYAMVDPEDISITELYRL-MEHRHRKKDTPVQ------------------ 196
Query: 125 XXXXXXXXXQSHHLMCSMRDFGHTAGGDEAELLLWLHDARRSQPLSERFRIRIARDGFSN 184
Q LMCS G+E E++ L D++ ++P+SERF +R+ R+G
Sbjct: 197 -ASSHHLFVQMKSLMCSNL-------GEELEVIFSLFDSKENRPISERFFLRLNRNGLPK 248
Query: 185 ------------YDLSTTDLTRELWLVAWVIRVXXXXXXXXXXXXXXXXXXPVARRPLGA 232
DL +++L +++++ +IR+ RRP G
Sbjct: 249 APDKPERHCSLFVDLGSSELRKDIYITVHIIRIGRMGAGEKKNACSVQY-----RRPFGC 303
Query: 233 GVLSLADFLRQTGQHPAEKEYTFKVYQCE-EKEFHQLHDMLIRKQTNKCNILPGQPNYGI 291
VLS+AD L TG+ + + KVY C E E++Q+H+ +I+K + N L G N G+
Sbjct: 304 AVLSIADLL--TGE--TKDDLILKVYMCNTESEWYQIHENIIKKLNARYN-LTGS-NAGL 357
Query: 292 VVALRLLANS-----GSVTEAVASGATITAKRGFPDVIMPGDVRNDLYLTLEKAEFERGG 346
V+L+LL + + G +IT K GF ++IMPG++RNDLY+T+E+ EFE+GG
Sbjct: 358 AVSLQLLHGDIEQIRREYSSVFSHGVSITRKLGFSNIIMPGEMRNDLYITIERGEFEKGG 417
Query: 347 KSTAKNVLATVTVHDNTGQVISDCVWGASGNGSTS-YESLVLYHNNSPAWGEQLRLTVPL 405
KS A+NV T+ + D++GQ + D + SG S Y S VLYHNNSP W E L+L +P+
Sbjct: 418 KSVARNVEVTMFIVDSSGQTLKDFISFGSGEPPASEYHSFVLYHNNSPRWSELLKLPIPV 477
Query: 406 ETFTHAHVRIEFRHCSTRDKNERKLFGFAFARLMEASGATLRDGAHELHVYKCDDPSKLL 465
+ F AH+R EFRHCST++K E+KLFGF+F LM+ G TL DG HEL V+KC++ + L
Sbjct: 478 DKFRGAHIRFEFRHCSTKEKGEKKLFGFSFVPLMQEDGRTLPDGTHELIVHKCEENTNLQ 537
Query: 466 -TASYLSLPSCANDAARAAPPNGVVPSFQRSSKENCTISTLLCSTKLTQNEDLLALLQWR 524
T YL LP G +++KE+ I++ LCSTKLTQN D+L LL+WR
Sbjct: 538 DTTRYLKLPFSKGIFL------GNNNQAMKATKESFCITSFLCSTKLTQNGDMLDLLKWR 591
Query: 525 AHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFSTEDGNSTPHSGTVFLVLIS 584
HP+K+ L ++ + DG E++KFL+D LD LF + D NS + VF L+
Sbjct: 592 THPDKITGCLSKLKEI-DG---SEIVKFLQDTLDTLFGIL---DENSQKYGSKVFDSLVH 644
Query: 585 ICSLLDESRFQHFKPVLDVYIEEHFSAALVYKGLLSSVQHCAEWAAGAEGQEPIRKCLRS 644
I +LL +S+F HFKPV+D YIE HF+ AL Y+ L+ ++ + AE QE I++ L++
Sbjct: 645 IINLLQDSKFHHFKPVMDTYIESHFAGALAYRDLIKVLKWYVDRITEAERQEHIQEVLKA 704
Query: 645 LGAVFRLAVQSRRLFARATGGQYEDSFRRDVRAALHALKAFAQHPHREH--LAPAQIALM 702
+F+ VQSRRLF+ ATGGQ E+ FR ++ L +++ F + L+ +Q +
Sbjct: 705 QEYIFKYIVQSRRLFSLATGGQNEEEFRCCIQELLMSVRFFLSQESKGSGALSQSQAVFL 764
Query: 703 TSWASVAREVSAALGAAETARV---SAAVLDAPVSXXXXXXXXXXXXXXXXXXGPLGEDP 759
+S+ +V E+ E A + + L + L +P
Sbjct: 765 SSFPAVYSELLKLFDVREVANLVQDTLGSLPTILHVDDSLQAIKLQCIGKTVESQLYTNP 824
Query: 760 EARNIILTTACHHLRVHLARRDELFQCAEMLGELVTLLWKKRXXXXXXXXXXXXXXXXXX 819
++R I+L HHL +HL + +L CA +L + L+ K
Sbjct: 825 DSRYILLPVVLHHLHIHLQEQKDLIMCARILSNVFCLIKKN------SSEKSVLEEIDVI 878
Query: 820 CLNTLDVLVETVLHLIGGNSP-----------VLGSMVAALLGVMELLRPIHYQRLWSHL 868
+ LD+L+ T+L + P V G VA LL ++ + HYQ+L
Sbjct: 879 VASLLDILLRTILEITSRPQPSSSAMRFQFQDVTGEFVACLLSLLRQMTDRHYQQLLDSF 938
Query: 869 APHPHDRKPLKDFLMRAFLVFRHLIEQDVFPPDWMVLRVQSCKVLLSALQDLAEPLLERF 928
+ ++ L+DFL++ F VFR LI ++FP DW V+R+ + V+++ + L++ L + F
Sbjct: 939 ----NTKEELRDFLLQIFTVFRILIRPEMFPKDWTVMRLVANNVIITTVLYLSDALRKNF 994
Query: 929 LGEEPPQFDTQLWSGYMELGVSLVTAGALQTERWHTPRMRAR 970
L E FD ++W Y L V + LQ E + TP + +
Sbjct: 995 LNE---NFDYKIWDSYFYLAVIFINQLCLQLEMF-TPSKKKK 1032
>AY233380-1|AAO73565.1| 1966|Homo sapiens DOCK4 protein.
Length = 1966
Score = 489 bits (1205), Expect = e-137
Identities = 318/942 (33%), Positives = 490/942 (52%), Gaps = 101/942 (10%)
Query: 65 KLGLELVPRRGAEAVEPEDISLVELYRVHVESAERAAAVRLRFYNFIIDIXXXXXXXXXX 124
+LGL+LVPR+ V+PEDIS+ ELYR+ +E R ++
Sbjct: 156 QLGLDLVPRKEYAMVDPEDISITELYRL-MEHRHRKKDTPVQ------------------ 196
Query: 125 XXXXXXXXXQSHHLMCSMRDFGHTAGGDEAELLLWLHDARRSQPLSERFRIRIARDGFSN 184
Q LMCS G+E E++ L D++ ++P+SERF +R+ R+G
Sbjct: 197 -ASSHHLFVQMKSLMCSNL-------GEELEVIFSLFDSKENRPISERFFLRLNRNGLPK 248
Query: 185 ------------YDLSTTDLTRELWLVAWVIRVXXXXXXXXXXXXXXXXXXPVARRPLGA 232
DL +++L +++++ +IR+ RRP G
Sbjct: 249 APDKPERHCSLFVDLGSSELRKDIYITVHIIRIGRMGAGEKKNACSVQY-----RRPFGC 303
Query: 233 GVLSLADFLRQTGQHPAEKEYTFKVYQCE-EKEFHQLHDMLIRKQTNKCNILPGQPNYGI 291
VLS+AD L TG+ + + KVY C E E++Q+H+ +I+K + N L G N G+
Sbjct: 304 AVLSIADLL--TGE--TKDDLILKVYMCNTESEWYQIHENIIKKLNARYN-LTGS-NAGL 357
Query: 292 VVALRLLANS-----GSVTEAVASGATITAKRGFPDVIMPGDVRNDLYLTLEKAEFERGG 346
V+L+LL + + G +IT K GF ++IMPG++RNDLY+T+E+ EFE+GG
Sbjct: 358 AVSLQLLHGDIEQIRREYSSVFSHGVSITRKLGFSNIIMPGEMRNDLYITIERGEFEKGG 417
Query: 347 KSTAKNVLATVTVHDNTGQVISDCVWGASGNGSTS-YESLVLYHNNSPAWGEQLRLTVPL 405
KS A+NV T+ + D++GQ + D + SG S Y S VLYHNNSP W E L+L +P+
Sbjct: 418 KSVARNVEVTMFIVDSSGQTLKDFISFGSGEPPASEYHSFVLYHNNSPRWSELLKLPIPV 477
Query: 406 ETFTHAHVRIEFRHCSTRDKNERKLFGFAFARLMEASGATLRDGAHELHVYKCDDPSKLL 465
+ F AH+R EFRHCST++K E+KLFGF+F LM+ G TL DG HEL V+KC++ + L
Sbjct: 478 DKFRGAHIRFEFRHCSTKEKGEKKLFGFSFVPLMQEDGRTLPDGTHELIVHKCEENTNLQ 537
Query: 466 -TASYLSLPSCANDAARAAPPNGVVPSFQRSSKENCTISTLLCSTKLTQNEDLLALLQWR 524
T YL LP G +++KE+ I++ LCSTKLTQN D+L LL+WR
Sbjct: 538 DTTRYLKLPFSKGIFL------GNNNQAMKATKESFCITSFLCSTKLTQNGDMLDLLKWR 591
Query: 525 AHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFSTEDGNSTPHSGTVFLVLIS 584
HP+K+ L ++ + DG E++KFL+D LD LF + D NS + VF L+
Sbjct: 592 THPDKITGCLSKLKEI-DG---SEIVKFLQDTLDTLFGIL---DENSQKYGSKVFDSLVH 644
Query: 585 ICSLLDESRFQHFKPVLDVYIEEHFSAALVYKGLLSSVQHCAEWAAGAEGQEPIRKCLRS 644
I +LL +S+F HFKPV+D YIE HF+ AL Y+ L+ ++ + AE QE I++ L++
Sbjct: 645 IINLLQDSKFHHFKPVMDTYIESHFAGALAYRDLIKVLKWYVDRITEAERQEHIQEVLKA 704
Query: 645 LGAVFRLAVQSRRLFARATGGQYEDSFRRDVRAALHALKAFAQHPHREH--LAPAQIALM 702
+F+ VQSRRLF+ ATGGQ E+ FR ++ L +++ F + L+ +Q +
Sbjct: 705 QEYIFKYIVQSRRLFSLATGGQNEEEFRCCIQELLMSVRFFLSQESKGSGALSQSQAVFL 764
Query: 703 TSWASVAREVSAALGAAETARV---SAAVLDAPVSXXXXXXXXXXXXXXXXXXGPLGEDP 759
+S+ +V E+ E A + + L + L +P
Sbjct: 765 SSFPAVYSELLKLFDVREVANLVQDTLGSLPTILHVDDSLQAIKLQCIGKTVESQLYTNP 824
Query: 760 EARNIILTTACHHLRVHLARRDELFQCAEMLGELVTLLWKKRXXXXXXXXXXXXXXXXXX 819
++R I+L HHL +HL + +L CA +L + L+ K
Sbjct: 825 DSRYILLPVVLHHLHIHLQEQKDLIMCARILSNVFCLIKKN------SSEKSVLEEIDVI 878
Query: 820 CLNTLDVLVETVLHLIGGNSP-----------VLGSMVAALLGVMELLRPIHYQRLWSHL 868
+ LD+L+ T+L + P V G VA LL ++ + HYQ+L
Sbjct: 879 VASLLDILLRTILEITSRPQPSSSAMRFQFQDVTGEFVACLLSLLRQMTDRHYQQLLDSF 938
Query: 869 APHPHDRKPLKDFLMRAFLVFRHLIEQDVFPPDWMVLRVQSCKVLLSALQDLAEPLLERF 928
+ ++ L+DFL++ F VFR LI ++FP DW V+R+ + V+++ + L++ L + F
Sbjct: 939 ----NTKEELRDFLLQIFTVFRILIRPEMFPKDWTVMRLVANNVIITTVLYLSDALRKNF 994
Query: 929 LGEEPPQFDTQLWSGYMELGVSLVTAGALQTERWHTPRMRAR 970
L E FD ++W Y L V + LQ E + TP + +
Sbjct: 995 LNE---NFDYKIWDSYFYLAVIFINQLCLQLEMF-TPSKKKK 1032
>BC117689-1|AAI17690.1| 2011|Homo sapiens DOCK4 protein protein.
Length = 2011
Score = 427 bits (1051), Expect = e-118
Identities = 275/806 (34%), Positives = 420/806 (52%), Gaps = 82/806 (10%)
Query: 65 KLGLELVPRRGAEAVEPEDISLVELYRVHVESAERAAAVRLRFYNFIIDIXXXXXXXXXX 124
+LGL+LVPR+ V+PEDIS+ ELYR+ +E R ++
Sbjct: 156 QLGLDLVPRKEYAMVDPEDISITELYRL-MEHRHRKKDTPVQ------------------ 196
Query: 125 XXXXXXXXXQSHHLMCSMRDFGHTAGGDEAELLLWLHDARRSQPLSERFRIRIARDGFSN 184
Q LMCS G+E E++ L D++ ++P+SERF +R+ R+G
Sbjct: 197 -ASSHHLFVQMKSLMCSNL-------GEELEVIFSLFDSKENRPISERFFLRLNRNGLPK 248
Query: 185 ------------YDLSTTDLTRELWLVAWVIRVXXXXXXXXXXXXXXXXXXPVARRPLGA 232
DL +++L +++++ +IR+ RRP G
Sbjct: 249 APDKPERHCSLFVDLGSSELRKDIYITVHIIRIGRMGAGEKKNACSVQY-----RRPFGC 303
Query: 233 GVLSLADFLRQTGQHPAEKEYTFKVYQCE-EKEFHQLHDMLIRKQTNKCNILPGQPNYGI 291
VLS+AD L TG+ + + KVY C E E++Q+H+ +I+K + N L G N G+
Sbjct: 304 AVLSIADLL--TGE--TKDDLILKVYMCNTESEWYQIHENIIKKLNARYN-LTGS-NAGL 357
Query: 292 VVALRLLANS-----GSVTEAVASGATITAKRGFPDVIMPGDVRNDLYLTLEKAEFERGG 346
V+L+LL + + G +IT K GF ++IMPG++RNDLY+T+E+ EFE+GG
Sbjct: 358 AVSLQLLHGDIEQIRREYSSVFSHGVSITRKLGFSNIIMPGEMRNDLYITIERGEFEKGG 417
Query: 347 KSTAKNVLATVTVHDNTGQVISDCVWGASGNGSTS-YESLVLYHNNSPAWGEQLRLTVPL 405
KS A+NV T+ + D++GQ + D + SG S Y S VLYHNNSP W E L+L +P+
Sbjct: 418 KSVARNVEVTMFIVDSSGQTLKDFISFGSGEPPASEYHSFVLYHNNSPRWSELLKLPIPV 477
Query: 406 ETFTHAHVRIEFRHCSTRDKNERKLFGFAFARLMEASGATLRDGAHELHVYKCDDPSKLL 465
+ F AH+R EFR CST++K E+KLFGF+F LM+ G TL DG HEL V+KC++ + L
Sbjct: 478 DKFRGAHIRFEFRRCSTKEKGEKKLFGFSFVPLMQEDGRTLPDGTHELIVHKCEENTNLQ 537
Query: 466 -TASYLSLPSCANDAARAAPPNGVVPSFQRSSKENCTISTLLCSTKLTQNEDLLALLQWR 524
T YL LP G +++KE+ I++ LCSTKLTQN D+L LL+WR
Sbjct: 538 DTTRYLKLPFSKGIFL------GNNNQAMKATKESFCITSFLCSTKLTQNGDMLDLLKWR 591
Query: 525 AHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFSTEDGNSTPHSGTVFLVLIS 584
HP+K+ L ++ + DG E++KFL+D LD LF + D NS + VF L+
Sbjct: 592 THPDKITGCLSKLKEI-DG---SEIVKFLQDTLDTLFGIL---DENSQKYGSKVFDSLVH 644
Query: 585 ICSLLDESRFQHFKPVLDVYIEEHFSAALVYKGLLSSVQHCAEWAAGAEGQEPIRKCLRS 644
I +LL +S+F HFKPV+D YIE HF+ AL Y+ L+ ++ + AE QE I++ L++
Sbjct: 645 IINLLQDSKFHHFKPVMDTYIESHFAGALAYRDLIKVLKWYVDRITEAERQEHIQEVLKA 704
Query: 645 LGAVFRLAVQSRRLFARATGGQYEDSFRRDVRAALHALKAFAQHPHREH--LAPAQIALM 702
+F+ VQSRRLF+ ATGGQ E+ FR ++ L +++ F + L+ +Q +
Sbjct: 705 QEYIFKYIVQSRRLFSLATGGQNEEEFRCCIQELLMSVRFFLSQESKGSGALSQSQAVFL 764
Query: 703 TSWASVAREVSAALGAAETARV---SAAVLDAPVSXXXXXXXXXXXXXXXXXXGPLGEDP 759
+S+ +V E+ E A + + L + L +P
Sbjct: 765 SSFPAVYSELLKLFDVREVANLVQDTLGSLPTILHVDDSLQAIKLQCIGKTVESQLYTNP 824
Query: 760 EARNIILTTACHHLRVHLARRDELFQCAEMLGELVTLLWKKRXXXXXXXXXXXXXXXXXX 819
++R I+L HHL +HL + +L CA +L + L+ K
Sbjct: 825 DSRYILLPVVLHHLHIHLQEQKDLIMCARILSNVFCLIKKN------SSEKSVLEEIDVI 878
Query: 820 CLNTLDVLVETVLHLIGGNSPVLGSM 845
+ LD+L+ T+L + P +M
Sbjct: 879 VASLLDILLRTILEITSRPQPSSSAM 904
Score = 72.5 bits (170), Expect = 7e-12
Identities = 41/128 (32%), Positives = 69/128 (53%), Gaps = 8/128 (6%)
Query: 843 GSMVAALLGVMELLRPIHYQRLWSHLAPHPHDRKPLKDFLMRAFLVFRHLIEQDVFPPDW 902
G VA LL ++ + HYQ+L + ++ L+DFL++ F VFR LI ++FP DW
Sbjct: 949 GEFVACLLSLLRQMTDRHYQQLLDSF----NTKEELRDFLLQIFTVFRILIRPEMFPKDW 1004
Query: 903 MVLRVQSCKVLLSALQDLAEPLLERFLGEEPPQFDTQLWSGYMELGVSLVTAGALQTERW 962
V+R+ + V+++ + L++ L + FL E D ++W Y L V + LQ E +
Sbjct: 1005 TVMRLVANNVIITTVLYLSDALRKNFLNE---NLDYKIWDSYFYLAVIFINQLCLQLEMF 1061
Query: 963 HTPRMRAR 970
TP + +
Sbjct: 1062 -TPSKKKK 1068
>D50857-1|BAA09454.1| 1865|Homo sapiens DOCK180 protein protein.
Length = 1865
Score = 353 bits (869), Expect = 1e-96
Identities = 267/952 (28%), Positives = 453/952 (47%), Gaps = 76/952 (7%)
Query: 66 LGLELVPR-RGAEAVEPEDISLVELYRVHVESAERAAAVRLRFYNFIIDIXXXXXXXXXX 124
L L+LV R ++PE S + L+R H E A + RL+
Sbjct: 160 LDLDLVVRDEDGNILDPELTSTISLFRAH-EIASKQVEERLQEEKSQKQNIDINRQAKFA 218
Query: 125 XXXXXXXXXQSHHLMCSMRDFGHTAGGDEAELLLWLHDARRSQPLSERFRIRIARDGFSN 184
+++C + G++AE+L+ L+D S+ +SE + +R + G
Sbjct: 219 ATPSLALFVNLKNVVCKI--------GEDAEVLMSLYDPVESKFISENYLVRWSSSGLPK 270
Query: 185 ------------YDLSTTDLTRE-LWLVAWVIRVXXXXXXXXXXXXXXXXXXPVARRPLG 231
DL + DL RE + V ++RV RRP G
Sbjct: 271 DIDRLHNLRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDNNTRKLTSGL----RRPFG 326
Query: 232 AGVLSLADFLRQTGQHPAEKEYTFKVYQ--CEEKEFHQ--LHDMLIRKQTNKCNILPGQP 287
V+ + D + G+ E + F +Q E +F Q ++ ++ K+ N GQ
Sbjct: 327 VAVMDVTDIIN--GKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNH----KGQ- 379
Query: 288 NYGIVVALRLLANS-----GSVTEAVASGATITAKRGFPDVIMPGDVRNDLYLTLEKAEF 342
G+ V L+LL V + K GFP++IMPGDVRND+Y+TL + +F
Sbjct: 380 --GLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDF 437
Query: 343 ERGGKSTAKNVLATVTVHDNTGQVISDCVW-GASGNGSTSYESLVLYHNNSPAWGEQLRL 401
++G K+TAKNV TV+V+D G+ + ++ GA + Y+S++ Y P W E +++
Sbjct: 438 DKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKV 497
Query: 402 TVPLETFTHAHVRIEFRHCSTRDKNER--KLFGFAFARLMEASGATLRDGAHELHVYKCD 459
+P+E +H+R FRH S++D ++ K+F AF +LM G TLRDG H+L VYK +
Sbjct: 498 AIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAE 557
Query: 460 DPSKLLTASYLSLPSC-ANDAARAAPPNGVVPSFQRS---SKENCTISTLLCSTKLTQNE 515
A+YLSLPS A + G S SK++ ISTL+CSTKLTQN
Sbjct: 558 AKKLEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNV 617
Query: 516 DLLALLQWRAHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFSTEDGNSTPHS 575
DLL LL+WR++ +Q+ L +++++ G E++KFL+D LDALF + E+ S
Sbjct: 618 DLLGLLKWRSNTSLLQQNLRQLMKVDGG----EVVKFLQDTLDALFNIM-MENSESETFD 672
Query: 576 GTVFLVLISICSLLDESRFQHFKPVLDVYIEEHFSAALVYKGLLSSVQHCAEWAAGAEGQ 635
VF L+ I L+ + +FQHF PVL+ YI++HFSA L Y L +++ + A
Sbjct: 673 TLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGAEKPGVN 732
Query: 636 EPIRKCLRSLGAVFRLAVQSRRLFARATGGQYEDSFRRDVRAALHALKAFAQHPHREHLA 695
E + K +++L ++F+ V+SR LF + + E F + ++ +
Sbjct: 733 EQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDM-MSSMSDQTV 791
Query: 696 PAQIALMTSWASVAREVSAALGAAETARV-SAAVLDAPVSXXXXXXXXXXXXXXXXXXGP 754
+ A + ++ +V E +++ + +L+ P+
Sbjct: 792 RVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMG---LLTIQKLYCLIEIVHSD 848
Query: 755 LGEDPEARNIILTTACHHLRVHLARRDELFQCAEMLGELVTLLWKKRXXXXXXXXXXXXX 814
L + R I+L L+ HL R+++L C ++L ++ +L++K
Sbjct: 849 LFTQHDCREILLPMMTDQLKYHLERQEDLEACCQLLSHILEVLYRK----DVGPTQRHVQ 904
Query: 815 XXXXXCLNTLDVLVETVLHLIGGNSPVLGSMVAALLGVMELLRPIHYQRLWSHLAPHPHD 874
L T++ TV+ + G +S ++G+ VA + ++ + HY L +
Sbjct: 905 IIMEKLLRTVN---RTVISM-GRDSELIGNFVACMTAILRQMEDYHYAHL---IKTFGKM 957
Query: 875 RKPLKDFLMRAFLVFRHLIEQDVFPPDWMVLRVQSCKVLLSALQDLAEPLLERFLGEEPP 934
R + DFLM F++F++LI ++V+P DW+++ + KV L A+ A+ L ++FL +
Sbjct: 958 RTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFL--DQA 1015
Query: 935 QFDTQLWSGYMELGVSLVTAGALQTERWHTPRMRARAATHVLAVWNMLGYYI 986
F+ QLW+ Y L V+ +T +LQ E + + + RA+ + +G+ I
Sbjct: 1016 NFELQLWNNYFHLAVAFLTQESLQLENFSSAK-RAKILNKYGDMRRQIGFEI 1066
>BX470201-1|CAH72560.2| 1865|Homo sapiens dedicator of cytokinesis 1
protein.
Length = 1865
Score = 353 bits (869), Expect = 1e-96
Identities = 267/952 (28%), Positives = 453/952 (47%), Gaps = 76/952 (7%)
Query: 66 LGLELVPR-RGAEAVEPEDISLVELYRVHVESAERAAAVRLRFYNFIIDIXXXXXXXXXX 124
L L+LV R ++PE S + L+R H E A + RL+
Sbjct: 160 LDLDLVVRDEDGNILDPELTSTISLFRAH-EIASKQVEERLQEEKSQKQNIDINRQAKFA 218
Query: 125 XXXXXXXXXQSHHLMCSMRDFGHTAGGDEAELLLWLHDARRSQPLSERFRIRIARDGFSN 184
+++C + G++AE+L+ L+D S+ +SE + +R + G
Sbjct: 219 ATPSLALFVNLKNVVCKI--------GEDAEVLMSLYDPVESKFISENYLVRWSSSGLPK 270
Query: 185 ------------YDLSTTDLTRE-LWLVAWVIRVXXXXXXXXXXXXXXXXXXPVARRPLG 231
DL + DL RE + V ++RV RRP G
Sbjct: 271 DIDRLHNLRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDNNTRKLTSGL----RRPFG 326
Query: 232 AGVLSLADFLRQTGQHPAEKEYTFKVYQ--CEEKEFHQ--LHDMLIRKQTNKCNILPGQP 287
V+ + D + G+ E + F +Q E +F Q ++ ++ K+ N GQ
Sbjct: 327 VAVMDVTDIIN--GKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNH----KGQ- 379
Query: 288 NYGIVVALRLLANS-----GSVTEAVASGATITAKRGFPDVIMPGDVRNDLYLTLEKAEF 342
G+ V L+LL V + K GFP++IMPGDVRND+Y+TL + +F
Sbjct: 380 --GLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDF 437
Query: 343 ERGGKSTAKNVLATVTVHDNTGQVISDCVW-GASGNGSTSYESLVLYHNNSPAWGEQLRL 401
++G K+TAKNV TV+V+D G+ + ++ GA + Y+S++ Y P W E +++
Sbjct: 438 DKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKV 497
Query: 402 TVPLETFTHAHVRIEFRHCSTRDKNER--KLFGFAFARLMEASGATLRDGAHELHVYKCD 459
+P+E +H+R FRH S++D ++ K+F AF +LM G TLRDG H+L VYK +
Sbjct: 498 AIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAE 557
Query: 460 DPSKLLTASYLSLPSC-ANDAARAAPPNGVVPSFQRS---SKENCTISTLLCSTKLTQNE 515
A+YLSLPS A + G S SK++ ISTL+CSTKLTQN
Sbjct: 558 AKKLEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNV 617
Query: 516 DLLALLQWRAHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFSTEDGNSTPHS 575
DLL LL+WR++ +Q+ L +++++ G E++KFL+D LDALF + E+ S
Sbjct: 618 DLLGLLKWRSNTSLLQQNLRQLMKVDGG----EVVKFLQDTLDALFNIM-MENSESETFD 672
Query: 576 GTVFLVLISICSLLDESRFQHFKPVLDVYIEEHFSAALVYKGLLSSVQHCAEWAAGAEGQ 635
VF L+ I L+ + +FQHF PVL+ YI++HFSA L Y L +++ + A
Sbjct: 673 TLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGAEKPGVN 732
Query: 636 EPIRKCLRSLGAVFRLAVQSRRLFARATGGQYEDSFRRDVRAALHALKAFAQHPHREHLA 695
E + K +++L ++F+ V+SR LF + + E F + ++ +
Sbjct: 733 EQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDM-MSSMSDQTV 791
Query: 696 PAQIALMTSWASVAREVSAALGAAETARV-SAAVLDAPVSXXXXXXXXXXXXXXXXXXGP 754
+ A + ++ +V E +++ + +L+ P+
Sbjct: 792 RVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMG---LLTIQKLYCLIEIVHSD 848
Query: 755 LGEDPEARNIILTTACHHLRVHLARRDELFQCAEMLGELVTLLWKKRXXXXXXXXXXXXX 814
L + R I+L L+ HL R+++L C ++L ++ +L++K
Sbjct: 849 LFTQHDCREILLPMMTDQLKYHLERQEDLEACCQLLSHILEVLYRK----DVGPTQRHVQ 904
Query: 815 XXXXXCLNTLDVLVETVLHLIGGNSPVLGSMVAALLGVMELLRPIHYQRLWSHLAPHPHD 874
L T++ TV+ + G +S ++G+ VA + ++ + HY L +
Sbjct: 905 IIMEKLLRTVN---RTVISM-GRDSELIGNFVACMTAILRQMEDYHYAHL---IKTFGKM 957
Query: 875 RKPLKDFLMRAFLVFRHLIEQDVFPPDWMVLRVQSCKVLLSALQDLAEPLLERFLGEEPP 934
R + DFLM F++F++LI ++V+P DW+++ + KV L A+ A+ L ++FL +
Sbjct: 958 RTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFL--DQA 1015
Query: 935 QFDTQLWSGYMELGVSLVTAGALQTERWHTPRMRARAATHVLAVWNMLGYYI 986
F+ QLW+ Y L V+ +T +LQ E + + + RA+ + +G+ I
Sbjct: 1016 NFELQLWNNYFHLAVAFLTQESLQLENFSSAK-RAKILNKYGDMRRQIGFEI 1066
>BX470155-1|CAI22477.2| 1865|Homo sapiens dedicator of cytokinesis 1
protein.
Length = 1865
Score = 353 bits (869), Expect = 1e-96
Identities = 267/952 (28%), Positives = 453/952 (47%), Gaps = 76/952 (7%)
Query: 66 LGLELVPR-RGAEAVEPEDISLVELYRVHVESAERAAAVRLRFYNFIIDIXXXXXXXXXX 124
L L+LV R ++PE S + L+R H E A + RL+
Sbjct: 160 LDLDLVVRDEDGNILDPELTSTISLFRAH-EIASKQVEERLQEEKSQKQNIDINRQAKFA 218
Query: 125 XXXXXXXXXQSHHLMCSMRDFGHTAGGDEAELLLWLHDARRSQPLSERFRIRIARDGFSN 184
+++C + G++AE+L+ L+D S+ +SE + +R + G
Sbjct: 219 ATPSLALFVNLKNVVCKI--------GEDAEVLMSLYDPVESKFISENYLVRWSSSGLPK 270
Query: 185 ------------YDLSTTDLTRE-LWLVAWVIRVXXXXXXXXXXXXXXXXXXPVARRPLG 231
DL + DL RE + V ++RV RRP G
Sbjct: 271 DIDRLHNLRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDNNTRKLTSGL----RRPFG 326
Query: 232 AGVLSLADFLRQTGQHPAEKEYTFKVYQ--CEEKEFHQ--LHDMLIRKQTNKCNILPGQP 287
V+ + D + G+ E + F +Q E +F Q ++ ++ K+ N GQ
Sbjct: 327 VAVMDVTDIIN--GKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNH----KGQ- 379
Query: 288 NYGIVVALRLLANS-----GSVTEAVASGATITAKRGFPDVIMPGDVRNDLYLTLEKAEF 342
G+ V L+LL V + K GFP++IMPGDVRND+Y+TL + +F
Sbjct: 380 --GLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDF 437
Query: 343 ERGGKSTAKNVLATVTVHDNTGQVISDCVW-GASGNGSTSYESLVLYHNNSPAWGEQLRL 401
++G K+TAKNV TV+V+D G+ + ++ GA + Y+S++ Y P W E +++
Sbjct: 438 DKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKV 497
Query: 402 TVPLETFTHAHVRIEFRHCSTRDKNER--KLFGFAFARLMEASGATLRDGAHELHVYKCD 459
+P+E +H+R FRH S++D ++ K+F AF +LM G TLRDG H+L VYK +
Sbjct: 498 AIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAE 557
Query: 460 DPSKLLTASYLSLPSC-ANDAARAAPPNGVVPSFQRS---SKENCTISTLLCSTKLTQNE 515
A+YLSLPS A + G S SK++ ISTL+CSTKLTQN
Sbjct: 558 AKKLEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNV 617
Query: 516 DLLALLQWRAHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFSTEDGNSTPHS 575
DLL LL+WR++ +Q+ L +++++ G E++KFL+D LDALF + E+ S
Sbjct: 618 DLLGLLKWRSNTSLLQQNLRQLMKVDGG----EVVKFLQDTLDALFNIM-MENSESETFD 672
Query: 576 GTVFLVLISICSLLDESRFQHFKPVLDVYIEEHFSAALVYKGLLSSVQHCAEWAAGAEGQ 635
VF L+ I L+ + +FQHF PVL+ YI++HFSA L Y L +++ + A
Sbjct: 673 TLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGAEKPGVN 732
Query: 636 EPIRKCLRSLGAVFRLAVQSRRLFARATGGQYEDSFRRDVRAALHALKAFAQHPHREHLA 695
E + K +++L ++F+ V+SR LF + + E F + ++ +
Sbjct: 733 EQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDM-MSSMSDQTV 791
Query: 696 PAQIALMTSWASVAREVSAALGAAETARV-SAAVLDAPVSXXXXXXXXXXXXXXXXXXGP 754
+ A + ++ +V E +++ + +L+ P+
Sbjct: 792 RVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMG---LLTIQKLYCLIEIVHSD 848
Query: 755 LGEDPEARNIILTTACHHLRVHLARRDELFQCAEMLGELVTLLWKKRXXXXXXXXXXXXX 814
L + R I+L L+ HL R+++L C ++L ++ +L++K
Sbjct: 849 LFTQHDCREILLPMMTDQLKYHLERQEDLEACCQLLSHILEVLYRK----DVGPTQRHVQ 904
Query: 815 XXXXXCLNTLDVLVETVLHLIGGNSPVLGSMVAALLGVMELLRPIHYQRLWSHLAPHPHD 874
L T++ TV+ + G +S ++G+ VA + ++ + HY L +
Sbjct: 905 IIMEKLLRTVN---RTVISM-GRDSELIGNFVACMTAILRQMEDYHYAHL---IKTFGKM 957
Query: 875 RKPLKDFLMRAFLVFRHLIEQDVFPPDWMVLRVQSCKVLLSALQDLAEPLLERFLGEEPP 934
R + DFLM F++F++LI ++V+P DW+++ + KV L A+ A+ L ++FL +
Sbjct: 958 RTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFL--DQA 1015
Query: 935 QFDTQLWSGYMELGVSLVTAGALQTERWHTPRMRARAATHVLAVWNMLGYYI 986
F+ QLW+ Y L V+ +T +LQ E + + + RA+ + +G+ I
Sbjct: 1016 NFELQLWNNYFHLAVAFLTQESLQLENFSSAK-RAKILNKYGDMRRQIGFEI 1066
>AL607029-1|CAI15329.2| 1865|Homo sapiens dedicator of cytokinesis 1
protein.
Length = 1865
Score = 353 bits (869), Expect = 1e-96
Identities = 267/952 (28%), Positives = 453/952 (47%), Gaps = 76/952 (7%)
Query: 66 LGLELVPR-RGAEAVEPEDISLVELYRVHVESAERAAAVRLRFYNFIIDIXXXXXXXXXX 124
L L+LV R ++PE S + L+R H E A + RL+
Sbjct: 160 LDLDLVVRDEDGNILDPELTSTISLFRAH-EIASKQVEERLQEEKSQKQNIDINRQAKFA 218
Query: 125 XXXXXXXXXQSHHLMCSMRDFGHTAGGDEAELLLWLHDARRSQPLSERFRIRIARDGFSN 184
+++C + G++AE+L+ L+D S+ +SE + +R + G
Sbjct: 219 ATPSLALFVNLKNVVCKI--------GEDAEVLMSLYDPVESKFISENYLVRWSSSGLPK 270
Query: 185 ------------YDLSTTDLTRE-LWLVAWVIRVXXXXXXXXXXXXXXXXXXPVARRPLG 231
DL + DL RE + V ++RV RRP G
Sbjct: 271 DIDRLHNLRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDNNTRKLTSGL----RRPFG 326
Query: 232 AGVLSLADFLRQTGQHPAEKEYTFKVYQ--CEEKEFHQ--LHDMLIRKQTNKCNILPGQP 287
V+ + D + G+ E + F +Q E +F Q ++ ++ K+ N GQ
Sbjct: 327 VAVMDVTDIIN--GKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNH----KGQ- 379
Query: 288 NYGIVVALRLLANS-----GSVTEAVASGATITAKRGFPDVIMPGDVRNDLYLTLEKAEF 342
G+ V L+LL V + K GFP++IMPGDVRND+Y+TL + +F
Sbjct: 380 --GLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDF 437
Query: 343 ERGGKSTAKNVLATVTVHDNTGQVISDCVW-GASGNGSTSYESLVLYHNNSPAWGEQLRL 401
++G K+TAKNV TV+V+D G+ + ++ GA + Y+S++ Y P W E +++
Sbjct: 438 DKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKV 497
Query: 402 TVPLETFTHAHVRIEFRHCSTRDKNER--KLFGFAFARLMEASGATLRDGAHELHVYKCD 459
+P+E +H+R FRH S++D ++ K+F AF +LM G TLRDG H+L VYK +
Sbjct: 498 AIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAE 557
Query: 460 DPSKLLTASYLSLPSC-ANDAARAAPPNGVVPSFQRS---SKENCTISTLLCSTKLTQNE 515
A+YLSLPS A + G S SK++ ISTL+CSTKLTQN
Sbjct: 558 AKKLEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNV 617
Query: 516 DLLALLQWRAHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFSTEDGNSTPHS 575
DLL LL+WR++ +Q+ L +++++ G E++KFL+D LDALF + E+ S
Sbjct: 618 DLLGLLKWRSNTSLLQQNLRQLMKVDGG----EVVKFLQDTLDALFNIM-MENSESETFD 672
Query: 576 GTVFLVLISICSLLDESRFQHFKPVLDVYIEEHFSAALVYKGLLSSVQHCAEWAAGAEGQ 635
VF L+ I L+ + +FQHF PVL+ YI++HFSA L Y L +++ + A
Sbjct: 673 TLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGAEKPGVN 732
Query: 636 EPIRKCLRSLGAVFRLAVQSRRLFARATGGQYEDSFRRDVRAALHALKAFAQHPHREHLA 695
E + K +++L ++F+ V+SR LF + + E F + ++ +
Sbjct: 733 EQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDM-MSSMSDQTV 791
Query: 696 PAQIALMTSWASVAREVSAALGAAETARV-SAAVLDAPVSXXXXXXXXXXXXXXXXXXGP 754
+ A + ++ +V E +++ + +L+ P+
Sbjct: 792 RVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMG---LLTIQKLYCLIEIVHSD 848
Query: 755 LGEDPEARNIILTTACHHLRVHLARRDELFQCAEMLGELVTLLWKKRXXXXXXXXXXXXX 814
L + R I+L L+ HL R+++L C ++L ++ +L++K
Sbjct: 849 LFTQHDCREILLPMMTDQLKYHLERQEDLEACCQLLSHILEVLYRK----DVGPTQRHVQ 904
Query: 815 XXXXXCLNTLDVLVETVLHLIGGNSPVLGSMVAALLGVMELLRPIHYQRLWSHLAPHPHD 874
L T++ TV+ + G +S ++G+ VA + ++ + HY L +
Sbjct: 905 IIMEKLLRTVN---RTVISM-GRDSELIGNFVACMTAILRQMEDYHYAHL---IKTFGKM 957
Query: 875 RKPLKDFLMRAFLVFRHLIEQDVFPPDWMVLRVQSCKVLLSALQDLAEPLLERFLGEEPP 934
R + DFLM F++F++LI ++V+P DW+++ + KV L A+ A+ L ++FL +
Sbjct: 958 RTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFL--DQA 1015
Query: 935 QFDTQLWSGYMELGVSLVTAGALQTERWHTPRMRARAATHVLAVWNMLGYYI 986
F+ QLW+ Y L V+ +T +LQ E + + + RA+ + +G+ I
Sbjct: 1016 NFELQLWNNYFHLAVAFLTQESLQLENFSSAK-RAKILNKYGDMRRQIGFEI 1066
>AL390920-1|CAH73231.2| 1865|Homo sapiens dedicator of cytokinesis 1
protein.
Length = 1865
Score = 353 bits (869), Expect = 1e-96
Identities = 267/952 (28%), Positives = 453/952 (47%), Gaps = 76/952 (7%)
Query: 66 LGLELVPR-RGAEAVEPEDISLVELYRVHVESAERAAAVRLRFYNFIIDIXXXXXXXXXX 124
L L+LV R ++PE S + L+R H E A + RL+
Sbjct: 160 LDLDLVVRDEDGNILDPELTSTISLFRAH-EIASKQVEERLQEEKSQKQNIDINRQAKFA 218
Query: 125 XXXXXXXXXQSHHLMCSMRDFGHTAGGDEAELLLWLHDARRSQPLSERFRIRIARDGFSN 184
+++C + G++AE+L+ L+D S+ +SE + +R + G
Sbjct: 219 ATPSLALFVNLKNVVCKI--------GEDAEVLMSLYDPVESKFISENYLVRWSSSGLPK 270
Query: 185 ------------YDLSTTDLTRE-LWLVAWVIRVXXXXXXXXXXXXXXXXXXPVARRPLG 231
DL + DL RE + V ++RV RRP G
Sbjct: 271 DIDRLHNLRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDNNTRKLTSGL----RRPFG 326
Query: 232 AGVLSLADFLRQTGQHPAEKEYTFKVYQ--CEEKEFHQ--LHDMLIRKQTNKCNILPGQP 287
V+ + D + G+ E + F +Q E +F Q ++ ++ K+ N GQ
Sbjct: 327 VAVMDVTDIIN--GKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNH----KGQ- 379
Query: 288 NYGIVVALRLLANS-----GSVTEAVASGATITAKRGFPDVIMPGDVRNDLYLTLEKAEF 342
G+ V L+LL V + K GFP++IMPGDVRND+Y+TL + +F
Sbjct: 380 --GLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDF 437
Query: 343 ERGGKSTAKNVLATVTVHDNTGQVISDCVW-GASGNGSTSYESLVLYHNNSPAWGEQLRL 401
++G K+TAKNV TV+V+D G+ + ++ GA + Y+S++ Y P W E +++
Sbjct: 438 DKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKV 497
Query: 402 TVPLETFTHAHVRIEFRHCSTRDKNER--KLFGFAFARLMEASGATLRDGAHELHVYKCD 459
+P+E +H+R FRH S++D ++ K+F AF +LM G TLRDG H+L VYK +
Sbjct: 498 AIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAE 557
Query: 460 DPSKLLTASYLSLPSC-ANDAARAAPPNGVVPSFQRS---SKENCTISTLLCSTKLTQNE 515
A+YLSLPS A + G S SK++ ISTL+CSTKLTQN
Sbjct: 558 AKKLEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNV 617
Query: 516 DLLALLQWRAHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFSTEDGNSTPHS 575
DLL LL+WR++ +Q+ L +++++ G E++KFL+D LDALF + E+ S
Sbjct: 618 DLLGLLKWRSNTSLLQQNLRQLMKVDGG----EVVKFLQDTLDALFNIM-MENSESETFD 672
Query: 576 GTVFLVLISICSLLDESRFQHFKPVLDVYIEEHFSAALVYKGLLSSVQHCAEWAAGAEGQ 635
VF L+ I L+ + +FQHF PVL+ YI++HFSA L Y L +++ + A
Sbjct: 673 TLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGAEKPGVN 732
Query: 636 EPIRKCLRSLGAVFRLAVQSRRLFARATGGQYEDSFRRDVRAALHALKAFAQHPHREHLA 695
E + K +++L ++F+ V+SR LF + + E F + ++ +
Sbjct: 733 EQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDM-MSSMSDQTV 791
Query: 696 PAQIALMTSWASVAREVSAALGAAETARV-SAAVLDAPVSXXXXXXXXXXXXXXXXXXGP 754
+ A + ++ +V E +++ + +L+ P+
Sbjct: 792 RVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMG---LLTIQKLYCLIEIVHSD 848
Query: 755 LGEDPEARNIILTTACHHLRVHLARRDELFQCAEMLGELVTLLWKKRXXXXXXXXXXXXX 814
L + R I+L L+ HL R+++L C ++L ++ +L++K
Sbjct: 849 LFTQHDCREILLPMMTDQLKYHLERQEDLEACCQLLSHILEVLYRK----DVGPTQRHVQ 904
Query: 815 XXXXXCLNTLDVLVETVLHLIGGNSPVLGSMVAALLGVMELLRPIHYQRLWSHLAPHPHD 874
L T++ TV+ + G +S ++G+ VA + ++ + HY L +
Sbjct: 905 IIMEKLLRTVN---RTVISM-GRDSELIGNFVACMTAILRQMEDYHYAHL---IKTFGKM 957
Query: 875 RKPLKDFLMRAFLVFRHLIEQDVFPPDWMVLRVQSCKVLLSALQDLAEPLLERFLGEEPP 934
R + DFLM F++F++LI ++V+P DW+++ + KV L A+ A+ L ++FL +
Sbjct: 958 RTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFL--DQA 1015
Query: 935 QFDTQLWSGYMELGVSLVTAGALQTERWHTPRMRARAATHVLAVWNMLGYYI 986
F+ QLW+ Y L V+ +T +LQ E + + + RA+ + +G+ I
Sbjct: 1016 NFELQLWNNYFHLAVAFLTQESLQLENFSSAK-RAKILNKYGDMRRQIGFEI 1066
>AL359094-1|CAH71477.2| 1865|Homo sapiens dedicator of cytokinesis 1
protein.
Length = 1865
Score = 353 bits (869), Expect = 1e-96
Identities = 267/952 (28%), Positives = 453/952 (47%), Gaps = 76/952 (7%)
Query: 66 LGLELVPR-RGAEAVEPEDISLVELYRVHVESAERAAAVRLRFYNFIIDIXXXXXXXXXX 124
L L+LV R ++PE S + L+R H E A + RL+
Sbjct: 160 LDLDLVVRDEDGNILDPELTSTISLFRAH-EIASKQVEERLQEEKSQKQNIDINRQAKFA 218
Query: 125 XXXXXXXXXQSHHLMCSMRDFGHTAGGDEAELLLWLHDARRSQPLSERFRIRIARDGFSN 184
+++C + G++AE+L+ L+D S+ +SE + +R + G
Sbjct: 219 ATPSLALFVNLKNVVCKI--------GEDAEVLMSLYDPVESKFISENYLVRWSSSGLPK 270
Query: 185 ------------YDLSTTDLTRE-LWLVAWVIRVXXXXXXXXXXXXXXXXXXPVARRPLG 231
DL + DL RE + V ++RV RRP G
Sbjct: 271 DIDRLHNLRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDNNTRKLTSGL----RRPFG 326
Query: 232 AGVLSLADFLRQTGQHPAEKEYTFKVYQ--CEEKEFHQ--LHDMLIRKQTNKCNILPGQP 287
V+ + D + G+ E + F +Q E +F Q ++ ++ K+ N GQ
Sbjct: 327 VAVMDVTDIIN--GKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNH----KGQ- 379
Query: 288 NYGIVVALRLLANS-----GSVTEAVASGATITAKRGFPDVIMPGDVRNDLYLTLEKAEF 342
G+ V L+LL V + K GFP++IMPGDVRND+Y+TL + +F
Sbjct: 380 --GLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDF 437
Query: 343 ERGGKSTAKNVLATVTVHDNTGQVISDCVW-GASGNGSTSYESLVLYHNNSPAWGEQLRL 401
++G K+TAKNV TV+V+D G+ + ++ GA + Y+S++ Y P W E +++
Sbjct: 438 DKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKV 497
Query: 402 TVPLETFTHAHVRIEFRHCSTRDKNER--KLFGFAFARLMEASGATLRDGAHELHVYKCD 459
+P+E +H+R FRH S++D ++ K+F AF +LM G TLRDG H+L VYK +
Sbjct: 498 AIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAE 557
Query: 460 DPSKLLTASYLSLPSC-ANDAARAAPPNGVVPSFQRS---SKENCTISTLLCSTKLTQNE 515
A+YLSLPS A + G S SK++ ISTL+CSTKLTQN
Sbjct: 558 AKKLEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNV 617
Query: 516 DLLALLQWRAHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFSTEDGNSTPHS 575
DLL LL+WR++ +Q+ L +++++ G E++KFL+D LDALF + E+ S
Sbjct: 618 DLLGLLKWRSNTSLLQQNLRQLMKVDGG----EVVKFLQDTLDALFNIM-MENSESETFD 672
Query: 576 GTVFLVLISICSLLDESRFQHFKPVLDVYIEEHFSAALVYKGLLSSVQHCAEWAAGAEGQ 635
VF L+ I L+ + +FQHF PVL+ YI++HFSA L Y L +++ + A
Sbjct: 673 TLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGAEKPGVN 732
Query: 636 EPIRKCLRSLGAVFRLAVQSRRLFARATGGQYEDSFRRDVRAALHALKAFAQHPHREHLA 695
E + K +++L ++F+ V+SR LF + + E F + ++ +
Sbjct: 733 EQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDM-MSSMSDQTV 791
Query: 696 PAQIALMTSWASVAREVSAALGAAETARV-SAAVLDAPVSXXXXXXXXXXXXXXXXXXGP 754
+ A + ++ +V E +++ + +L+ P+
Sbjct: 792 RVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMG---LLTIQKLYCLIEIVHSD 848
Query: 755 LGEDPEARNIILTTACHHLRVHLARRDELFQCAEMLGELVTLLWKKRXXXXXXXXXXXXX 814
L + R I+L L+ HL R+++L C ++L ++ +L++K
Sbjct: 849 LFTQHDCREILLPMMTDQLKYHLERQEDLEACCQLLSHILEVLYRK----DVGPTQRHVQ 904
Query: 815 XXXXXCLNTLDVLVETVLHLIGGNSPVLGSMVAALLGVMELLRPIHYQRLWSHLAPHPHD 874
L T++ TV+ + G +S ++G+ VA + ++ + HY L +
Sbjct: 905 IIMEKLLRTVN---RTVISM-GRDSELIGNFVACMTAILRQMEDYHYAHL---IKTFGKM 957
Query: 875 RKPLKDFLMRAFLVFRHLIEQDVFPPDWMVLRVQSCKVLLSALQDLAEPLLERFLGEEPP 934
R + DFLM F++F++LI ++V+P DW+++ + KV L A+ A+ L ++FL +
Sbjct: 958 RTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFL--DQA 1015
Query: 935 QFDTQLWSGYMELGVSLVTAGALQTERWHTPRMRARAATHVLAVWNMLGYYI 986
F+ QLW+ Y L V+ +T +LQ E + + + RA+ + +G+ I
Sbjct: 1016 NFELQLWNNYFHLAVAFLTQESLQLENFSSAK-RAKILNKYGDMRRQIGFEI 1066
>AL355316-1|CAI16871.2| 1865|Homo sapiens dedicator of cytokinesis 1
protein.
Length = 1865
Score = 353 bits (869), Expect = 1e-96
Identities = 267/952 (28%), Positives = 453/952 (47%), Gaps = 76/952 (7%)
Query: 66 LGLELVPR-RGAEAVEPEDISLVELYRVHVESAERAAAVRLRFYNFIIDIXXXXXXXXXX 124
L L+LV R ++PE S + L+R H E A + RL+
Sbjct: 160 LDLDLVVRDEDGNILDPELTSTISLFRAH-EIASKQVEERLQEEKSQKQNIDINRQAKFA 218
Query: 125 XXXXXXXXXQSHHLMCSMRDFGHTAGGDEAELLLWLHDARRSQPLSERFRIRIARDGFSN 184
+++C + G++AE+L+ L+D S+ +SE + +R + G
Sbjct: 219 ATPSLALFVNLKNVVCKI--------GEDAEVLMSLYDPVESKFISENYLVRWSSSGLPK 270
Query: 185 ------------YDLSTTDLTRE-LWLVAWVIRVXXXXXXXXXXXXXXXXXXPVARRPLG 231
DL + DL RE + V ++RV RRP G
Sbjct: 271 DIDRLHNLRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDNNTRKLTSGL----RRPFG 326
Query: 232 AGVLSLADFLRQTGQHPAEKEYTFKVYQ--CEEKEFHQ--LHDMLIRKQTNKCNILPGQP 287
V+ + D + G+ E + F +Q E +F Q ++ ++ K+ N GQ
Sbjct: 327 VAVMDVTDIIN--GKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNH----KGQ- 379
Query: 288 NYGIVVALRLLANS-----GSVTEAVASGATITAKRGFPDVIMPGDVRNDLYLTLEKAEF 342
G+ V L+LL V + K GFP++IMPGDVRND+Y+TL + +F
Sbjct: 380 --GLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDF 437
Query: 343 ERGGKSTAKNVLATVTVHDNTGQVISDCVW-GASGNGSTSYESLVLYHNNSPAWGEQLRL 401
++G K+TAKNV TV+V+D G+ + ++ GA + Y+S++ Y P W E +++
Sbjct: 438 DKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKV 497
Query: 402 TVPLETFTHAHVRIEFRHCSTRDKNER--KLFGFAFARLMEASGATLRDGAHELHVYKCD 459
+P+E +H+R FRH S++D ++ K+F AF +LM G TLRDG H+L VYK +
Sbjct: 498 AIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAE 557
Query: 460 DPSKLLTASYLSLPSC-ANDAARAAPPNGVVPSFQRS---SKENCTISTLLCSTKLTQNE 515
A+YLSLPS A + G S SK++ ISTL+CSTKLTQN
Sbjct: 558 AKKLEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNV 617
Query: 516 DLLALLQWRAHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFSTEDGNSTPHS 575
DLL LL+WR++ +Q+ L +++++ G E++KFL+D LDALF + E+ S
Sbjct: 618 DLLGLLKWRSNTSLLQQNLRQLMKVDGG----EVVKFLQDTLDALFNIM-MENSESETFD 672
Query: 576 GTVFLVLISICSLLDESRFQHFKPVLDVYIEEHFSAALVYKGLLSSVQHCAEWAAGAEGQ 635
VF L+ I L+ + +FQHF PVL+ YI++HFSA L Y L +++ + A
Sbjct: 673 TLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGAEKPGVN 732
Query: 636 EPIRKCLRSLGAVFRLAVQSRRLFARATGGQYEDSFRRDVRAALHALKAFAQHPHREHLA 695
E + K +++L ++F+ V+SR LF + + E F + ++ +
Sbjct: 733 EQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDM-MSSMSDQTV 791
Query: 696 PAQIALMTSWASVAREVSAALGAAETARV-SAAVLDAPVSXXXXXXXXXXXXXXXXXXGP 754
+ A + ++ +V E +++ + +L+ P+
Sbjct: 792 RVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMG---LLTIQKLYCLIEIVHSD 848
Query: 755 LGEDPEARNIILTTACHHLRVHLARRDELFQCAEMLGELVTLLWKKRXXXXXXXXXXXXX 814
L + R I+L L+ HL R+++L C ++L ++ +L++K
Sbjct: 849 LFTQHDCREILLPMMTDQLKYHLERQEDLEACCQLLSHILEVLYRK----DVGPTQRHVQ 904
Query: 815 XXXXXCLNTLDVLVETVLHLIGGNSPVLGSMVAALLGVMELLRPIHYQRLWSHLAPHPHD 874
L T++ TV+ + G +S ++G+ VA + ++ + HY L +
Sbjct: 905 IIMEKLLRTVN---RTVISM-GRDSELIGNFVACMTAILRQMEDYHYAHL---IKTFGKM 957
Query: 875 RKPLKDFLMRAFLVFRHLIEQDVFPPDWMVLRVQSCKVLLSALQDLAEPLLERFLGEEPP 934
R + DFLM F++F++LI ++V+P DW+++ + KV L A+ A+ L ++FL +
Sbjct: 958 RTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFL--DQA 1015
Query: 935 QFDTQLWSGYMELGVSLVTAGALQTERWHTPRMRARAATHVLAVWNMLGYYI 986
F+ QLW+ Y L V+ +T +LQ E + + + RA+ + +G+ I
Sbjct: 1016 NFELQLWNNYFHLAVAFLTQESLQLENFSSAK-RAKILNKYGDMRRQIGFEI 1066
>AL157711-1|CAH71463.2| 1865|Homo sapiens dedicator of cytokinesis 1
protein.
Length = 1865
Score = 353 bits (869), Expect = 1e-96
Identities = 267/952 (28%), Positives = 453/952 (47%), Gaps = 76/952 (7%)
Query: 66 LGLELVPR-RGAEAVEPEDISLVELYRVHVESAERAAAVRLRFYNFIIDIXXXXXXXXXX 124
L L+LV R ++PE S + L+R H E A + RL+
Sbjct: 160 LDLDLVVRDEDGNILDPELTSTISLFRAH-EIASKQVEERLQEEKSQKQNIDINRQAKFA 218
Query: 125 XXXXXXXXXQSHHLMCSMRDFGHTAGGDEAELLLWLHDARRSQPLSERFRIRIARDGFSN 184
+++C + G++AE+L+ L+D S+ +SE + +R + G
Sbjct: 219 ATPSLALFVNLKNVVCKI--------GEDAEVLMSLYDPVESKFISENYLVRWSSSGLPK 270
Query: 185 ------------YDLSTTDLTRE-LWLVAWVIRVXXXXXXXXXXXXXXXXXXPVARRPLG 231
DL + DL RE + V ++RV RRP G
Sbjct: 271 DIDRLHNLRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDNNTRKLTSGL----RRPFG 326
Query: 232 AGVLSLADFLRQTGQHPAEKEYTFKVYQ--CEEKEFHQ--LHDMLIRKQTNKCNILPGQP 287
V+ + D + G+ E + F +Q E +F Q ++ ++ K+ N GQ
Sbjct: 327 VAVMDVTDIIN--GKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNH----KGQ- 379
Query: 288 NYGIVVALRLLANS-----GSVTEAVASGATITAKRGFPDVIMPGDVRNDLYLTLEKAEF 342
G+ V L+LL V + K GFP++IMPGDVRND+Y+TL + +F
Sbjct: 380 --GLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDF 437
Query: 343 ERGGKSTAKNVLATVTVHDNTGQVISDCVW-GASGNGSTSYESLVLYHNNSPAWGEQLRL 401
++G K+TAKNV TV+V+D G+ + ++ GA + Y+S++ Y P W E +++
Sbjct: 438 DKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKV 497
Query: 402 TVPLETFTHAHVRIEFRHCSTRDKNER--KLFGFAFARLMEASGATLRDGAHELHVYKCD 459
+P+E +H+R FRH S++D ++ K+F AF +LM G TLRDG H+L VYK +
Sbjct: 498 AIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAE 557
Query: 460 DPSKLLTASYLSLPSC-ANDAARAAPPNGVVPSFQRS---SKENCTISTLLCSTKLTQNE 515
A+YLSLPS A + G S SK++ ISTL+CSTKLTQN
Sbjct: 558 AKKLEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNV 617
Query: 516 DLLALLQWRAHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFSTEDGNSTPHS 575
DLL LL+WR++ +Q+ L +++++ G E++KFL+D LDALF + E+ S
Sbjct: 618 DLLGLLKWRSNTSLLQQNLRQLMKVDGG----EVVKFLQDTLDALFNIM-MENSESETFD 672
Query: 576 GTVFLVLISICSLLDESRFQHFKPVLDVYIEEHFSAALVYKGLLSSVQHCAEWAAGAEGQ 635
VF L+ I L+ + +FQHF PVL+ YI++HFSA L Y L +++ + A
Sbjct: 673 TLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGAEKPGVN 732
Query: 636 EPIRKCLRSLGAVFRLAVQSRRLFARATGGQYEDSFRRDVRAALHALKAFAQHPHREHLA 695
E + K +++L ++F+ V+SR LF + + E F + ++ +
Sbjct: 733 EQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDM-MSSMSDQTV 791
Query: 696 PAQIALMTSWASVAREVSAALGAAETARV-SAAVLDAPVSXXXXXXXXXXXXXXXXXXGP 754
+ A + ++ +V E +++ + +L+ P+
Sbjct: 792 RVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMG---LLTIQKLYCLIEIVHSD 848
Query: 755 LGEDPEARNIILTTACHHLRVHLARRDELFQCAEMLGELVTLLWKKRXXXXXXXXXXXXX 814
L + R I+L L+ HL R+++L C ++L ++ +L++K
Sbjct: 849 LFTQHDCREILLPMMTDQLKYHLERQEDLEACCQLLSHILEVLYRK----DVGPTQRHVQ 904
Query: 815 XXXXXCLNTLDVLVETVLHLIGGNSPVLGSMVAALLGVMELLRPIHYQRLWSHLAPHPHD 874
L T++ TV+ + G +S ++G+ VA + ++ + HY L +
Sbjct: 905 IIMEKLLRTVN---RTVISM-GRDSELIGNFVACMTAILRQMEDYHYAHL---IKTFGKM 957
Query: 875 RKPLKDFLMRAFLVFRHLIEQDVFPPDWMVLRVQSCKVLLSALQDLAEPLLERFLGEEPP 934
R + DFLM F++F++LI ++V+P DW+++ + KV L A+ A+ L ++FL +
Sbjct: 958 RTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFL--DQA 1015
Query: 935 QFDTQLWSGYMELGVSLVTAGALQTERWHTPRMRARAATHVLAVWNMLGYYI 986
F+ QLW+ Y L V+ +T +LQ E + + + RA+ + +G+ I
Sbjct: 1016 NFELQLWNNYFHLAVAFLTQESLQLENFSSAK-RAKILNKYGDMRRQIGFEI 1066
>D86964-1|BAA13200.1| 1842|Homo sapiens KIAA0209 protein.
Length = 1842
Score = 331 bits (814), Expect = 6e-90
Identities = 258/927 (27%), Positives = 428/927 (46%), Gaps = 68/927 (7%)
Query: 66 LGLELVPR-RGAEAVEPEDISLVELYRVHVESAERAAAVRLRFYNFIIDIXXXXXXXXXX 124
L L+L+ R ++P++ S++ L+ H E+ ++ R++
Sbjct: 171 LELDLIVRDEDGNILDPDNTSVISLFHAHEEATDKITE-RIK--------EEMSKDQPDY 221
Query: 125 XXXXXXXXXQSHHLMCSMRDFGHTAGGDEAELLLWLHDARRSQPLSERFRIRIARDGFSN 184
+H L +R+F G D AEL + L+D + +SE + +R GF
Sbjct: 222 AMYSRISSSPTHSLYVFVRNFVCRIGED-AELFMSLYDPNKQTVISENYLVRWGSRGFPK 280
Query: 185 Y------------DLSTTDLTRE-LWLVAWVIRVXXXXXXXXXXXXXXXXXXPVARRPLG 231
DL DL R+ ++L+ ++RV RRP G
Sbjct: 281 EIEMLNNLKVVFTDLGNKDLNRDKIYLICQIVRVGKMDLKDTGAKKCTQGL----RRPFG 336
Query: 232 AGVLSLADFLRQTGQHPAEKEYTFKVYQCE-EKEFHQLHDMLIRKQTNKCNILPGQPNYG 290
V+ + D ++ + EK++ + E +F LH +L + +K + GQ G
Sbjct: 337 VAVMDITDIIKGKAESDEEKQHFIPFHPVTAENDF--LHSLLGKVIASKGDS-GGQ---G 390
Query: 291 IVVALRLLANS-----GSVTEAVASGATITAKRGFPDVIMPGDVRNDLYLTLEKAEFERG 345
+ V +++L V + K GFP++IMPGDVRND+Y+TL + +F++
Sbjct: 391 LWVTMKMLVGDIIQIRKDYPHLVDRTTVVARKLGFPEIIMPGDVRNDIYITLLQGDFDKY 450
Query: 346 GKSTAKNVLATVTVHDNTGQVISDCVW-GASGNGSTSYESLVLYHNNSPAWGEQLRLTVP 404
K+T +NV + V G+ + + + GA Y S+V Y P W E +++ VP
Sbjct: 451 NKTTQRNVEVIMCVCAEDGKTLPNAICVGAGDKPMNEYRSVVYYQVKQPRWMETVKVAVP 510
Query: 405 LETFTHAHVRIEFRHCST---RDKNERKLFGFAFARLMEASGATLRDGAHELHVYKCDDP 461
+E H+R FRH S+ +DK E+ F ++ +LM+ G TL DG H+L V K D
Sbjct: 511 IEDMQRIHLRFMFRHRSSLESKDKGEKN-FAMSYVKLMKEDGTTLHDGFHDLVVLKGDSK 569
Query: 462 SKLLTASYLSLPS----CANDAARAAPPNGVVPSFQRSSKENCTISTLLCSTKLTQNEDL 517
++YL+LPS N A + + V SS++ +ISTL+CSTKLTQN L
Sbjct: 570 KMEDASAYLTLPSYRHHVENKGATLSRSSSSVGGLSVSSRDVFSISTLVCSTKLTQNVGL 629
Query: 518 LALLQWRAHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFSTEDGNSTPHSGT 577
L LL+WR P+ +QE L + L++ DG EE++KFL+D LDALF + E S +
Sbjct: 630 LGLLKWRMKPQLLQENLEK-LKIVDG---EEVVKFLQDTLDALFNIMM-EHSQSDEYDIL 684
Query: 578 VFLVLISICSLLDESRFQHFKPVLDVYIEEHFSAALVYKGLLSSVQHCAEWAAGAEGQEP 637
VF LI I L+ + +FQHF VL+ YI++HFSA L YK L++ ++ + ++ E EP
Sbjct: 685 VFDALIYIIGLIADRKFQHFNTVLEAYIQQHFSATLAYKKLMTVLKTYLDTSSRGEQCEP 744
Query: 638 IRKCLRSLGAVFRLAVQSRRLFARATGGQYEDSFRRDVRAALHALKAFAQHPHREHLAPA 697
I + L++L VF+ V+SR LF++ G+ + F +R ++ + ++ +
Sbjct: 745 ILRTLKALEYVFKFIVRSRTLFSQLYEGKEQMEFEESMRRLFESINNLMKSQYKTTIL-L 803
Query: 698 QIALMTSWASVAREVSAALGAAETARVSAAVLDA--PVSXXXXXXXXXXXXXXXXXXGPL 755
Q+A + SV +V A +++ PV L
Sbjct: 804 QVAALKYIPSVLHDVEMVFDAKLLSQLLYEFYTCIPPVKLQKQKVQSMNEIVQSN----L 859
Query: 756 GEDPEARNIILTTACHHLRVHLARRDELFQCAEMLGELVTLLWKKRXXXXXXXXXXXXXX 815
+ E R+I+L L+ L ++D++ V LL
Sbjct: 860 FKKQECRDILLPVITKELKELLEQKDDMQHQVLERKYCVELLNSILEVLSYQDAAFTYHH 919
Query: 816 XXXXCLNTLDVLVETVLHLIGGNSPVLGSMVAALLGVMELLRPIHYQRLWSHLAPHPHDR 875
+ L + TV+ +G + ++ VA + ++ + HY S
Sbjct: 920 IQEIMVQLLRTVNRTVI-TMGRDHILISHFVACMTAILNQMGDQHY----SFYIETFQTS 974
Query: 876 KPLKDFLMRAFLVFRHLIEQDVFPPDWMVLRVQSCKVLLSALQDLAEPLLERFLGEEPPQ 935
L DFLM F++F+ LI ++V+P DWM + + +V L A+ AE + ++FL E
Sbjct: 975 SELVDFLMETFIMFKDLIGKNVYPGDWMAMSMVQNRVFLRAINKFAETMNQKFL--EHTN 1032
Query: 936 FDTQLWSGYMELGVSLVTAGALQTERW 962
F+ QLW+ Y L V+ +T +LQ E++
Sbjct: 1033 FEFQLWNNYFHLAVAFITQDSLQLEQF 1059
>BC113457-1|AAI13458.1| 1830|Homo sapiens dedicator of cytokinesis 2
protein.
Length = 1830
Score = 331 bits (814), Expect = 6e-90
Identities = 258/927 (27%), Positives = 428/927 (46%), Gaps = 68/927 (7%)
Query: 66 LGLELVPR-RGAEAVEPEDISLVELYRVHVESAERAAAVRLRFYNFIIDIXXXXXXXXXX 124
L L+L+ R ++P++ S++ L+ H E+ ++ R++
Sbjct: 159 LELDLIVRDEDGNILDPDNTSVISLFHAHEEATDKITE-RIK--------EEMSKDQPDY 209
Query: 125 XXXXXXXXXQSHHLMCSMRDFGHTAGGDEAELLLWLHDARRSQPLSERFRIRIARDGFSN 184
+H L +R+F G D AEL + L+D + +SE + +R GF
Sbjct: 210 AMYSRISSSPTHSLYVFVRNFVCRIGED-AELFMSLYDPNKQTVISENYLVRWGSRGFPK 268
Query: 185 Y------------DLSTTDLTRE-LWLVAWVIRVXXXXXXXXXXXXXXXXXXPVARRPLG 231
DL DL R+ ++L+ ++RV RRP G
Sbjct: 269 EIEMLNNLKVVFTDLGNKDLNRDKIYLICQIVRVGKMDLKDTGAKKCTQGL----RRPFG 324
Query: 232 AGVLSLADFLRQTGQHPAEKEYTFKVYQCE-EKEFHQLHDMLIRKQTNKCNILPGQPNYG 290
V+ + D ++ + EK++ + E +F LH +L + +K + GQ G
Sbjct: 325 VAVMDITDIIKGKAESDEEKQHFIPFHPVTAENDF--LHSLLGKVIASKGDS-GGQ---G 378
Query: 291 IVVALRLLANS-----GSVTEAVASGATITAKRGFPDVIMPGDVRNDLYLTLEKAEFERG 345
+ V +++L V + K GFP++IMPGDVRND+Y+TL + +F++
Sbjct: 379 LWVTMKMLVGDIIQIRKDYPHLVDRTTVVARKLGFPEIIMPGDVRNDIYITLLQGDFDKY 438
Query: 346 GKSTAKNVLATVTVHDNTGQVISDCVW-GASGNGSTSYESLVLYHNNSPAWGEQLRLTVP 404
K+T +NV + V G+ + + + GA Y S+V Y P W E +++ VP
Sbjct: 439 NKTTQRNVEVIMCVCAEDGKTLPNAICVGAGDKPMNEYRSVVYYQVKQPRWMETVKVAVP 498
Query: 405 LETFTHAHVRIEFRHCST---RDKNERKLFGFAFARLMEASGATLRDGAHELHVYKCDDP 461
+E H+R FRH S+ +DK E+ F ++ +LM+ G TL DG H+L V K D
Sbjct: 499 IEDMQRIHLRFMFRHRSSLESKDKGEKN-FAMSYVKLMKEDGTTLHDGFHDLVVLKGDSK 557
Query: 462 SKLLTASYLSLPS----CANDAARAAPPNGVVPSFQRSSKENCTISTLLCSTKLTQNEDL 517
++YL+LPS N A + + V SS++ +ISTL+CSTKLTQN L
Sbjct: 558 KMEDASAYLTLPSYRHHVENKGATLSRSSSSVGGLSVSSRDVFSISTLVCSTKLTQNVGL 617
Query: 518 LALLQWRAHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFSTEDGNSTPHSGT 577
L LL+WR P+ +QE L + L++ DG EE++KFL+D LDALF + E S +
Sbjct: 618 LGLLKWRMKPQLLQENLEK-LKIVDG---EEVVKFLQDTLDALFNIMM-EHSQSDEYDIL 672
Query: 578 VFLVLISICSLLDESRFQHFKPVLDVYIEEHFSAALVYKGLLSSVQHCAEWAAGAEGQEP 637
VF LI I L+ + +FQHF VL+ YI++HFSA L YK L++ ++ + ++ E EP
Sbjct: 673 VFDALIYIIGLIADRKFQHFNTVLEAYIQQHFSATLAYKKLMTVLKTYLDTSSRGEQCEP 732
Query: 638 IRKCLRSLGAVFRLAVQSRRLFARATGGQYEDSFRRDVRAALHALKAFAQHPHREHLAPA 697
I + L++L VF+ V+SR LF++ G+ + F +R ++ + ++ +
Sbjct: 733 ILRTLKALEYVFKFIVRSRTLFSQLYEGKEQMEFEESMRRLFESINNLMKSQYKTTIL-L 791
Query: 698 QIALMTSWASVAREVSAALGAAETARVSAAVLDA--PVSXXXXXXXXXXXXXXXXXXGPL 755
Q+A + SV +V A +++ PV L
Sbjct: 792 QVAALKYIPSVLHDVEMVFDAKLLSQLLYEFYTCIPPVKLQKQKVQSMNEIVQSN----L 847
Query: 756 GEDPEARNIILTTACHHLRVHLARRDELFQCAEMLGELVTLLWKKRXXXXXXXXXXXXXX 815
+ E R+I+L L+ L ++D++ V LL
Sbjct: 848 FKKQECRDILLPVITKELKELLEQKDDMQHQVLERKYCVELLNSILEVLSYQDAAFTYHH 907
Query: 816 XXXXCLNTLDVLVETVLHLIGGNSPVLGSMVAALLGVMELLRPIHYQRLWSHLAPHPHDR 875
+ L + TV+ +G + ++ VA + ++ + HY S
Sbjct: 908 IQEIMVQLLRTVNRTVI-TMGRDHILISHFVACMTAILNQMGDQHY----SFYIETFQTS 962
Query: 876 KPLKDFLMRAFLVFRHLIEQDVFPPDWMVLRVQSCKVLLSALQDLAEPLLERFLGEEPPQ 935
L DFLM F++F+ LI ++V+P DWM + + +V L A+ AE + ++FL E
Sbjct: 963 SELVDFLMETFIMFKDLIGKNVYPGDWMAMSMVQNRVFLRAINKFAETMNQKFL--EHTN 1020
Query: 936 FDTQLWSGYMELGVSLVTAGALQTERW 962
F+ QLW+ Y L V+ +T +LQ E++
Sbjct: 1021 FEFQLWNNYFHLAVAFITQDSLQLEQF 1047
>BC104900-1|AAI04901.1| 1830|Homo sapiens dedicator of cytokinesis 2
protein.
Length = 1830
Score = 331 bits (814), Expect = 6e-90
Identities = 258/927 (27%), Positives = 428/927 (46%), Gaps = 68/927 (7%)
Query: 66 LGLELVPR-RGAEAVEPEDISLVELYRVHVESAERAAAVRLRFYNFIIDIXXXXXXXXXX 124
L L+L+ R ++P++ S++ L+ H E+ ++ R++
Sbjct: 159 LELDLIVRDEDGNILDPDNTSVISLFHAHEEATDKITE-RIK--------EEMSKDQPDY 209
Query: 125 XXXXXXXXXQSHHLMCSMRDFGHTAGGDEAELLLWLHDARRSQPLSERFRIRIARDGFSN 184
+H L +R+F G D AEL + L+D + +SE + +R GF
Sbjct: 210 AMYSRISSSPTHSLYVFVRNFVCRIGED-AELFMSLYDPNKQTVISENYLVRWGSRGFPK 268
Query: 185 Y------------DLSTTDLTRE-LWLVAWVIRVXXXXXXXXXXXXXXXXXXPVARRPLG 231
DL DL R+ ++L+ ++RV RRP G
Sbjct: 269 EIEMLNNLKVVFTDLGNKDLNRDKIYLICQIVRVGKMDLKDTGAKKCTQGL----RRPFG 324
Query: 232 AGVLSLADFLRQTGQHPAEKEYTFKVYQCE-EKEFHQLHDMLIRKQTNKCNILPGQPNYG 290
V+ + D ++ + EK++ + E +F LH +L + +K + GQ G
Sbjct: 325 VAVMDITDIIKGKAESDEEKQHFIPFHPVTAENDF--LHSLLGKVIASKGDS-GGQ---G 378
Query: 291 IVVALRLLANS-----GSVTEAVASGATITAKRGFPDVIMPGDVRNDLYLTLEKAEFERG 345
+ V +++L V + K GFP++IMPGDVRND+Y+TL + +F++
Sbjct: 379 LWVTMKMLVGDIIQIRKDYPHLVDRTTVVARKLGFPEIIMPGDVRNDIYITLLQGDFDKY 438
Query: 346 GKSTAKNVLATVTVHDNTGQVISDCVW-GASGNGSTSYESLVLYHNNSPAWGEQLRLTVP 404
K+T +NV + V G+ + + + GA Y S+V Y P W E +++ VP
Sbjct: 439 NKTTQRNVEVIMCVCAEDGKTLPNAICVGAGDKPMNEYRSVVYYQVKQPRWMETVKVAVP 498
Query: 405 LETFTHAHVRIEFRHCST---RDKNERKLFGFAFARLMEASGATLRDGAHELHVYKCDDP 461
+E H+R FRH S+ +DK E+ F ++ +LM+ G TL DG H+L V K D
Sbjct: 499 IEDMQRIHLRFMFRHRSSLESKDKGEKN-FAMSYVKLMKEDGTTLHDGFHDLVVLKGDSK 557
Query: 462 SKLLTASYLSLPS----CANDAARAAPPNGVVPSFQRSSKENCTISTLLCSTKLTQNEDL 517
++YL+LPS N A + + V SS++ +ISTL+CSTKLTQN L
Sbjct: 558 KMEDASAYLTLPSYRHHVENKGATLSRSSSSVGGLSVSSRDVFSISTLVCSTKLTQNVGL 617
Query: 518 LALLQWRAHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFSTEDGNSTPHSGT 577
L LL+WR P+ +QE L + L++ DG EE++KFL+D LDALF + E S +
Sbjct: 618 LGLLKWRMKPQLLQENLEK-LKIVDG---EEVVKFLQDTLDALFNIMM-EHSQSDEYDIL 672
Query: 578 VFLVLISICSLLDESRFQHFKPVLDVYIEEHFSAALVYKGLLSSVQHCAEWAAGAEGQEP 637
VF LI I L+ + +FQHF VL+ YI++HFSA L YK L++ ++ + ++ E EP
Sbjct: 673 VFDALIYIIGLIADRKFQHFNTVLEAYIQQHFSATLAYKKLMTVLKTYLDTSSRGEQCEP 732
Query: 638 IRKCLRSLGAVFRLAVQSRRLFARATGGQYEDSFRRDVRAALHALKAFAQHPHREHLAPA 697
I + L++L VF+ V+SR LF++ G+ + F +R ++ + ++ +
Sbjct: 733 ILRTLKALEYVFKFIVRSRTLFSQLYEGKEQMEFEESMRRLFESINNLMKSQYKTTIL-L 791
Query: 698 QIALMTSWASVAREVSAALGAAETARVSAAVLDA--PVSXXXXXXXXXXXXXXXXXXGPL 755
Q+A + SV +V A +++ PV L
Sbjct: 792 QVAALKYIPSVLHDVEMVFDAKLLSQLLYEFYTCIPPVKLQKQKVQSMNEIVQSN----L 847
Query: 756 GEDPEARNIILTTACHHLRVHLARRDELFQCAEMLGELVTLLWKKRXXXXXXXXXXXXXX 815
+ E R+I+L L+ L ++D++ V LL
Sbjct: 848 FKKQECRDILLPVITKELKELLEQKDDMQHQVLERKYCVELLNSILEVLSYQDAAFTYHH 907
Query: 816 XXXXCLNTLDVLVETVLHLIGGNSPVLGSMVAALLGVMELLRPIHYQRLWSHLAPHPHDR 875
+ L + TV+ +G + ++ VA + ++ + HY S
Sbjct: 908 IQEIMVQLLRTVNRTVI-TMGRDHILISHFVACMTAILNQMGDQHY----SFYIETFQTS 962
Query: 876 KPLKDFLMRAFLVFRHLIEQDVFPPDWMVLRVQSCKVLLSALQDLAEPLLERFLGEEPPQ 935
L DFLM F++F+ LI ++V+P DWM + + +V L A+ AE + ++FL E
Sbjct: 963 SELVDFLMETFIMFKDLIGKNVYPGDWMAMSMVQNRVFLRAINKFAETMNQKFL--EHTN 1020
Query: 936 FDTQLWSGYMELGVSLVTAGALQTERW 962
F+ QLW+ Y L V+ +T +LQ E++
Sbjct: 1021 FEFQLWNNYFHLAVAFITQDSLQLEQF 1047
>AB018259-1|BAA34436.3| 1388|Homo sapiens KIAA0716 protein protein.
Length = 1388
Score = 247 bits (604), Expect = 2e-64
Identities = 156/493 (31%), Positives = 252/493 (51%), Gaps = 37/493 (7%)
Query: 494 RSSKENCTISTLLCSTKLTQNEDLLALLQWRAHPEKVQETLLRVLRLGDGLSCEELIKFL 553
+++KE+ I++ LCSTKLTQN D+L LL+WR HP+K+ L ++ + DG E++KFL
Sbjct: 12 KATKESFCITSFLCSTKLTQNGDMLDLLKWRTHPDKITGCLSKLKEI-DG---SEIVKFL 67
Query: 554 RDVLDALFALFSTEDGNSTPHSGTVFLVLISICSLLDESRFQHFKPVLDVYIEEHFSAAL 613
+D LD LF + D NS + VF L+ I +LL +S+F HFKPV+D YIE HF+ AL
Sbjct: 68 QDTLDTLFGIL---DENSQKYGSKVFDSLVHIINLLQDSKFHHFKPVMDTYIESHFAGAL 124
Query: 614 VYKGLLSSVQHCAEWAAGAEGQEPIRKCLRSLGAVFRLAVQSRRLFARATGGQYEDSFRR 673
Y+ L+ ++ + AE QE I++ L++ +F+ VQSRRLF+ ATGGQ E+ FR
Sbjct: 125 AYRDLIKVLKWYVDRITEAERQEHIQEVLKAQEYIFKYIVQSRRLFSLATGGQNEEEFRC 184
Query: 674 DVRAALHALKAFAQHPHREH--LAPAQIALMTSWASVAREVSAALGAAETARV---SAAV 728
++ L +++ F + L+ +Q ++S+ +V E+ E A + +
Sbjct: 185 CIQELLMSVRFFLSQESKGSGALSQSQAVFLSSFPAVYSELLKLFDVREVANLVQDTLGS 244
Query: 729 LDAPVSXXXXXXXXXXXXXXXXXXGPLGEDPEARNIILTTACHHLRVHLARRDELFQCAE 788
L + L +P++R I+L HHL +HL + +L CA
Sbjct: 245 LPTILHVDDSLQAIKLQCIGKTVESQLYTNPDSRYILLPVVLHHLHIHLQEQKDLIMCAR 304
Query: 789 MLGELVTLLWKKRXXXXXXXXXXXXXXXXXXCLNTLDVLVETVLHLIGGNSP-------- 840
+L + L+ K + LD+L+ T+L + P
Sbjct: 305 ILSNVFCLIKKN------SSEKSVLEEIDVIVASLLDILLRTILEITSRPQPSSSAMRFQ 358
Query: 841 ---VLGSMVAALLGVMELLRPIHYQRLWSHLAPHPHDRKPLKDFLMRAFLVFRHLIEQDV 897
V G VA LL ++ + HYQ+L + ++ L+DFL++ F VFR LI ++
Sbjct: 359 FQDVTGEFVACLLSLLRQMTDRHYQQLLDSF----NTKEELRDFLLQIFTVFRILIRPEM 414
Query: 898 FPPDWMVLRVQSCKVLLSALQDLAEPLLERFLGEEPPQFDTQLWSGYMELGVSLVTAGAL 957
FP DW V+R+ + V+++ + L++ L + FL E FD ++W Y L V + L
Sbjct: 415 FPKDWTVMRLVANNVIITTVLYLSDALRKNFLNE---NFDYKIWDSYFYLAVIFINQLCL 471
Query: 958 QTERWHTPRMRAR 970
Q E + TP + +
Sbjct: 472 QLEMF-TPSKKKK 483
>AK123607-1|BAC85660.1| 677|Homo sapiens protein ( Homo sapiens
cDNA FLJ41613 fis, clone CTONG3002412, moderately
similar to Human DOCK180 protein mRNA. ).
Length = 677
Score = 197 bits (480), Expect = 2e-49
Identities = 153/531 (28%), Positives = 244/531 (45%), Gaps = 32/531 (6%)
Query: 439 MEASGATLRDGAHELHVYKCDDPSKLLTASYLSLPSCANDAARA---APPNGVV--PSFQ 493
M G TL+DG H+L VYK D+ YL+LP + A N V PS +
Sbjct: 1 MNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEEKELQASKNLVTFTPS-K 59
Query: 494 RSSKENCTISTLLCSTKLTQNEDLLALLQWRAHPEKVQETLLRVLRLGDGLSCEELIKFL 553
S+K++ I+TL+CSTKLTQN DLL LL WR++ + ++ L +++ + G E++KFL
Sbjct: 60 DSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQNIKHNLKKLMEVDGG----EIVKFL 115
Query: 554 RDVLDALFALFSTEDGNSTPHSGTVFLVLISICSLLDESRFQHFKPVLDVYIEEHFSAAL 613
+D LDALF + E +S + VF L+ I SL+ + +FQHF PVL+ YI +HFSA L
Sbjct: 116 QDTLDALFNIMM-EMSDSETYDFLVFDALVFIISLIGDIKFQHFNPVLETYIYKHFSATL 174
Query: 614 VYKGLLSSVQHCAEWAAGAEGQEPIRKCLRSLGAVFRLAVQSRRLFARATGGQYE-DSFR 672
Y L + A + E + L++L +FR +QSR L+ R G + D F
Sbjct: 175 AYVKLSKVLNFYVANADDSSKTELLFAALKALKYLFRFIIQSRVLYLRFYGQSKDGDEFN 234
Query: 673 RDVRAALHALKAFAQHPHREHLAPAQIALMTSWASVAREVSAALGAAETARVSAAVLDAP 732
+R A P E + A + S+ +V E + + + +
Sbjct: 235 NSIRQLFLAFNMLMDRP-LEEAVKIKGAALKYLPSIINDVKLVFDPVELSVLFCKFIQSI 293
Query: 733 VSXXXXXXXXXXXXXXXXXXGPLGEDPEARNIILTTACHHLRVHL---ARRDELFQCAEM 789
L E R ++L L L + + + +++
Sbjct: 294 PDNQLVRQKLNCMTKIVEST--LFRQSECREVLLPLLTDQLSGQLDDNSNKPDHEASSQL 351
Query: 790 LGELVTLLWKKRXXXXXXXXXXXXXXXXXXCLNTLDVLVETVLHLIGGNSPVLGSMVAAL 849
L ++ +L +K L + TV+ + SP +GS VA +
Sbjct: 352 LSNILEVLDRKDVGATAVHIQLIME-------RLLRRINRTVIGM-NRQSPHIGSFVACM 403
Query: 850 LGVMELLRPIHYQRLWSHLAPHPHDRKPLKDFLMRAFLVFRHLIEQDVFPPDWMVLRVQS 909
+ +++ + HY SH R+ + DFLM F++F+ LI ++V+ DWMV+ +
Sbjct: 404 IALLQQMDDSHY----SHYISTFKTRQDIIDFLMETFIMFKDLIGKNVYAKDWMVMNMTQ 459
Query: 910 CKVLLSALQDLAEPLLERFLGEEPPQFDTQLWSGYMELGVSLVTAGALQTE 960
+V L A+ AE L F+ + F+ QLW+ Y L V+ +T +LQ E
Sbjct: 460 NRVFLRAINRFAEVLTRFFM--DQASFELQLWNNYFHLAVAFLTHESLQLE 508
>AK091557-1|BAC03696.1| 775|Homo sapiens protein ( Homo sapiens
cDNA FLJ34238 fis, clone FCBBF3027559, weakly similar to
Dedicator of cyto-kinesis 1. ).
Length = 775
Score = 155 bits (376), Expect = 7e-37
Identities = 107/386 (27%), Positives = 181/386 (46%), Gaps = 30/386 (7%)
Query: 601 LDVYIEEHFSAALVYKGLLSSVQHCAEWAAGAEGQEPIRKCLRSLGAVFRLAVQSRRLFA 660
+D YIE HF+ AL Y+ L+ ++ + AE QE I++ L++ +F+ VQSRRLF+
Sbjct: 1 MDTYIESHFAGALAYRDLIKVLKWYVDRITEAERQEHIQEVLKAQEYIFKYIVQSRRLFS 60
Query: 661 RATGGQYEDSFRRDVRAALHALKAFAQHPHREH--LAPAQIALMTSWASVAREVSAALGA 718
ATGGQ E+ FR ++ L +++ F + L+ +Q ++S+ +V E+
Sbjct: 61 LATGGQNEEEFRCCIQELLMSVRFFLSQESKGSGALSQSQAVFLSSFPAVYSELLKLFDV 120
Query: 719 AETARV---SAAVLDAPVSXXXXXXXXXXXXXXXXXXGPLGEDPEARNIILTTACHHLRV 775
E A + + L + L +P++R I+L HHL +
Sbjct: 121 REVANLVQDTLGSLPTILHVDDSLQAIKLQCIGKTVESQLYTNPDSRYILLPVVLHHLHI 180
Query: 776 HLARRDELFQCAEMLGELVTLLWKKRXXXXXXXXXXXXXXXXXXCLNTLDVLVETVLHLI 835
HL + +L CA +L + L+ K + LD+L+ T+L +
Sbjct: 181 HLQEQKDLIMCARILSNVFCLIKKN------SSEKSVLEEIDVIVASLLDILLRTILEIT 234
Query: 836 GGNSP-----------VLGSMVAALLGVMELLRPIHYQRLWSHLAPHPHDRKPLKDFLMR 884
P V G VA LL ++ + HYQ+L + ++ L+DFL++
Sbjct: 235 SRPQPSSSAMRFQFQDVTGEFVACLLSLLRQMTDRHYQQLLDSF----NTKEELRDFLLQ 290
Query: 885 AFLVFRHLIEQDVFPPDWMVLRVQSCKVLLSALQDLAEPLLERFLGEEPPQFDTQLWSGY 944
F VFR LI ++FP DW V+R+ + V+++ + L++ L + FL E FD ++W Y
Sbjct: 291 IFTVFRILIRPEMFPKDWTVMRLVANNVIITTVLYLSDALRKNFLNE---NFDYKIWDSY 347
Query: 945 MELGVSLVTAGALQTERWHTPRMRAR 970
L V + LQ E + TP + +
Sbjct: 348 FYLAVIFINQLCLQLEMF-TPSKKKK 372
>BC016996-1|AAH16996.1| 336|Homo sapiens DOCK2 protein protein.
Length = 336
Score = 97.9 bits (233), Expect = 2e-19
Identities = 58/149 (38%), Positives = 86/149 (57%), Gaps = 9/149 (6%)
Query: 396 GEQLRLTVPLETFTHAHVRIEFRHCST---RDKNERKLFGFAFARLMEASGATLRDGAHE 452
G+ L + VP+E H+R FRH S+ +DK E+ F ++ +LM+ G TL DG H+
Sbjct: 8 GKTLPVAVPIEDMQRIHLRFMFRHRSSLESKDKGEKN-FAMSYVKLMKEDGTTLHDGFHD 66
Query: 453 LHVYKCDDPSKLLTASYLSLPS----CANDAARAAPPNGVVPSFQRSSKENCTISTLLCS 508
L V K D ++YL+LPS N A + + V SS++ +ISTL+CS
Sbjct: 67 LVVLKGDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSSVGGLSVSSRDVFSISTLVCS 126
Query: 509 TKLTQNEDLLALLQWRAHPEKVQETLLRV 537
TKLTQN LL LL+WR P+ ++E++ R+
Sbjct: 127 TKLTQNVGLLGLLKWRMKPQ-LEESMRRL 154
>AK126249-1|BAC86503.1| 942|Homo sapiens protein ( Homo sapiens
cDNA FLJ44261 fis, clone TLIVE2001327, moderately
similar to Human DOCK180 protein mRNA. ).
Length = 942
Score = 78.6 bits (185), Expect = 1e-13
Identities = 44/129 (34%), Positives = 72/129 (55%), Gaps = 8/129 (6%)
Query: 834 LIGGN--SPVLGSMVAALLGVMELLRPIHYQRLWSHLAPHPHDRKPLKDFLMRAFLVFRH 891
+IG N SP +GS VA ++ +++ + HY SH R+ + DFL+ F++F+
Sbjct: 12 VIGMNRQSPHIGSFVACMIALLQQMDDSHY----SHYISTFKTRQDIIDFLLETFIMFKD 67
Query: 892 LIEQDVFPPDWMVLRVQSCKVLLSALQDLAEPLLERFLGEEPPQFDTQLWSGYMELGVSL 951
LI ++V+ DWMV+ + +V L A+ AE L F+ + F+ QLW+ Y L V+
Sbjct: 68 LIGKNVYAKDWMVMNMTQNRVFLRAINQFAEVLTRFFM--DQASFELQLWNNYFHLAVAF 125
Query: 952 VTAGALQTE 960
+T +LQ E
Sbjct: 126 LTHESLQLE 134
>BC084559-1|AAH84559.1| 152|Homo sapiens DOCK1 protein protein.
Length = 152
Score = 70.1 bits (164), Expect = 4e-11
Identities = 35/96 (36%), Positives = 60/96 (62%), Gaps = 5/96 (5%)
Query: 327 GDVRNDLYLTLEKAEFERGGKSTAKNVLATVTVHDNTGQVISDCVW-GASGNGSTSYESL 385
GDVRND+Y+TL + +F++G K+TAKNV TV+V+D G+ + ++ GA + Y+S+
Sbjct: 30 GDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSV 89
Query: 386 VLYHNNSPAWGEQLRLTVPLETFTHAHVRIEFRHCS 421
+ Y P W E +++ L T++ H+ + + CS
Sbjct: 90 IYYQVKQPRWFETVKV---LFTWSFYHMALIMK-CS 121
>AC003077-1|AAB83946.1| 843|Homo sapiens WUGSC:H_GS034D21.1
protein.
Length = 843
Score = 63.7 bits (148), Expect = 3e-09
Identities = 33/92 (35%), Positives = 53/92 (57%), Gaps = 4/92 (4%)
Query: 879 KDFLMRAFLVFRHLIEQDVFPPDWMVLRVQSCKVLLSALQDLAEPLLERFLGEEPPQFDT 938
KDFL++ F VFR LI ++FP DW V+R+ + V+++ + L++ L + FL E FD
Sbjct: 1 KDFLLQIFTVFRILIRPEMFPKDWTVMRLVANNVIITTVLYLSDALRKNFLNE---NFDY 57
Query: 939 QLWSGYMELGVSLVTAGALQTERWHTPRMRAR 970
++W Y L V + LQ E + TP + +
Sbjct: 58 KIWDSYFYLAVIFINQLCLQLEMF-TPSKKKK 88
>DQ341187-1|ABC68221.1| 2129|Homo sapiens dedicator of cytokinesis 7
protein.
Length = 2129
Score = 43.2 bits (97), Expect = 0.005
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 9/115 (7%)
Query: 322 DVIMPGDV-RNDLYLTLEKAEFERGGKSTAKNVLATVTVHDNTGQVISDC---VWGASGN 377
DV +P RN LY+ + F + +A+N+ TV V G+ S+ ++G S
Sbjct: 552 DVYVPNTTYRNLLYIYPQSLNFANR-QGSARNI--TVKVQFMYGEDPSNAMPVIFGKSSC 608
Query: 378 GSTSYESL--VLYHNNSPAWGEQLRLTVPLETFTHAHVRIEFRHCSTRDKNERKL 430
S E+ V+YHN SP + E++++ +P H H+ F H S + K L
Sbjct: 609 SEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHHLLFTFYHVSCQQKQNTPL 663
>DQ309763-1|ABC33725.1| 803|Homo sapiens dedicator of cytokinesis 7
splice variant 3 protein.
Length = 803
Score = 43.2 bits (97), Expect = 0.005
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 9/115 (7%)
Query: 322 DVIMPGDV-RNDLYLTLEKAEFERGGKSTAKNVLATVTVHDNTGQVISDC---VWGASGN 377
DV +P RN LY+ + F + +A+N+ TV V G+ S+ ++G S
Sbjct: 444 DVYVPNTTYRNLLYIYPQSLNFANR-QGSARNI--TVKVQFMYGEDPSNAMPVIFGKSSC 500
Query: 378 GSTSYESL--VLYHNNSPAWGEQLRLTVPLETFTHAHVRIEFRHCSTRDKNERKL 430
S E+ V+YHN SP + E++++ +P H H+ F H S + K L
Sbjct: 501 SEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHHLLFTFYHVSCQQKQNTPL 555
>DQ118680-1|AAZ38452.1| 1990|Homo sapiens dedicator of cytokinesis 7
protein.
Length = 1990
Score = 43.2 bits (97), Expect = 0.005
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 9/115 (7%)
Query: 322 DVIMPGDV-RNDLYLTLEKAEFERGGKSTAKNVLATVTVHDNTGQVISDC---VWGASGN 377
DV +P RN LY+ + F + +A+N+ TV V G+ S+ ++G S
Sbjct: 444 DVYVPNTTYRNLLYIYPQSLNFANR-QGSARNI--TVKVQFMYGEDPSNAMPVIFGKSSC 500
Query: 378 GSTSYESL--VLYHNNSPAWGEQLRLTVPLETFTHAHVRIEFRHCSTRDKNERKL 430
S E+ V+YHN SP + E++++ +P H H+ F H S + K L
Sbjct: 501 SEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHHLLFTFYHVSCQQKQNTPL 555
>DQ118679-1|AAZ38451.1| 1992|Homo sapiens dedicator of cytokinesis 7
protein.
Length = 1992
Score = 43.2 bits (97), Expect = 0.005
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 9/115 (7%)
Query: 322 DVIMPGDV-RNDLYLTLEKAEFERGGKSTAKNVLATVTVHDNTGQVISDC---VWGASGN 377
DV +P RN LY+ + F + +A+N+ TV V G+ S+ ++G S
Sbjct: 444 DVYVPNTTYRNLLYIYPQSLNFANR-QGSARNI--TVKVQFMYGEDPSNAMPVIFGKSSC 500
Query: 378 GSTSYESL--VLYHNNSPAWGEQLRLTVPLETFTHAHVRIEFRHCSTRDKNERKL 430
S E+ V+YHN SP + E++++ +P H H+ F H S + K L
Sbjct: 501 SEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHHLLFTFYHVSCQQKQNTPL 555
>AL451044-1|CAI13104.1| 2109|Homo sapiens dedicator of cytokinesis 7
protein.
Length = 2109
Score = 43.2 bits (97), Expect = 0.005
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 9/115 (7%)
Query: 322 DVIMPGDV-RNDLYLTLEKAEFERGGKSTAKNVLATVTVHDNTGQVISDC---VWGASGN 377
DV +P RN LY+ + F + +A+N+ TV V G+ S+ ++G S
Sbjct: 552 DVYVPNTTYRNLLYIYPQSLNFANR-QGSARNI--TVKVQFMYGEDPSNAMPVIFGKSSC 608
Query: 378 GSTSYESL--VLYHNNSPAWGEQLRLTVPLETFTHAHVRIEFRHCSTRDKNERKL 430
S E+ V+YHN SP + E++++ +P H H+ F H S + K L
Sbjct: 609 SEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHHLLFTFYHVSCQQKQNTPL 663
>AL138847-2|CAI22995.1| 2109|Homo sapiens dedicator of cytokinesis 7
protein.
Length = 2109
Score = 43.2 bits (97), Expect = 0.005
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 9/115 (7%)
Query: 322 DVIMPGDV-RNDLYLTLEKAEFERGGKSTAKNVLATVTVHDNTGQVISDC---VWGASGN 377
DV +P RN LY+ + F + +A+N+ TV V G+ S+ ++G S
Sbjct: 552 DVYVPNTTYRNLLYIYPQSLNFANR-QGSARNI--TVKVQFMYGEDPSNAMPVIFGKSSC 608
Query: 378 GSTSYESL--VLYHNNSPAWGEQLRLTVPLETFTHAHVRIEFRHCSTRDKNERKL 430
S E+ V+YHN SP + E++++ +P H H+ F H S + K L
Sbjct: 609 SEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHHLLFTFYHVSCQQKQNTPL 663
>AK125049-1|BAC86032.1| 1520|Homo sapiens protein ( Homo sapiens
cDNA FLJ43059 fis, clone BRTHA3007769. ).
Length = 1520
Score = 37.5 bits (83), Expect = 0.23
Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 371 VWGASGNGSTSYESL--VLYHNNSPAWGEQLRLTVPLETFTHAHVRIEFRHCSTRDKNER 428
++G S S E+ V+YHN SP + E++++ +P H H+ F H S + K
Sbjct: 13 IFGKSSCSEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHHLLFTFYHVSCQQKQNT 72
Query: 429 KL 430
L
Sbjct: 73 PL 74
>BC130518-1|AAI30519.1| 1999|Homo sapiens DOCK8 protein protein.
Length = 1999
Score = 36.7 bits (81), Expect = 0.41
Identities = 29/110 (26%), Positives = 55/110 (50%), Gaps = 9/110 (8%)
Query: 322 DVIMPGDV-RNDLYLTLEKAEFERGGKSTAKNVLATVTVHDNTGQVISDC---VWGASGN 377
+V +P V RN LY+ ++ F ++A+N+ T+ + G+ S+ ++G S
Sbjct: 483 EVYVPHTVYRNLLYVYPQRLNFVNK-LASARNI--TIKIQFMCGEDASNAMPVIFGKSSG 539
Query: 378 GSTSYE--SLVLYHNNSPAWGEQLRLTVPLETFTHAHVRIEFRHCSTRDK 425
E + V YHN SP + E++++ +P + + H+ F H S + K
Sbjct: 540 PEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQK 589
>AL161725-3|CAM13234.1| 2031|Homo sapiens dedicator of cytokinesis 8
protein.
Length = 2031
Score = 36.7 bits (81), Expect = 0.41
Identities = 29/110 (26%), Positives = 55/110 (50%), Gaps = 9/110 (8%)
Query: 322 DVIMPGDV-RNDLYLTLEKAEFERGGKSTAKNVLATVTVHDNTGQVISDC---VWGASGN 377
+V +P V RN LY+ ++ F ++A+N+ T+ + G+ S+ ++G S
Sbjct: 483 EVYVPHTVYRNLLYVYPQRLNFVNK-LASARNI--TIKIQFMCGEDASNAMPVIFGKSSG 539
Query: 378 GSTSYE--SLVLYHNNSPAWGEQLRLTVPLETFTHAHVRIEFRHCSTRDK 425
E + V YHN SP + E++++ +P + + H+ F H S + K
Sbjct: 540 PEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQK 589
>AL158832-3|CAM22536.1| 2031|Homo sapiens dedicator of cytokinesis 8
protein.
Length = 2031
Score = 36.7 bits (81), Expect = 0.41
Identities = 29/110 (26%), Positives = 55/110 (50%), Gaps = 9/110 (8%)
Query: 322 DVIMPGDV-RNDLYLTLEKAEFERGGKSTAKNVLATVTVHDNTGQVISDC---VWGASGN 377
+V +P V RN LY+ ++ F ++A+N+ T+ + G+ S+ ++G S
Sbjct: 483 EVYVPHTVYRNLLYVYPQRLNFVNK-LASARNI--TIKIQFMCGEDASNAMPVIFGKSSG 539
Query: 378 GSTSYE--SLVLYHNNSPAWGEQLRLTVPLETFTHAHVRIEFRHCSTRDK 425
E + V YHN SP + E++++ +P + + H+ F H S + K
Sbjct: 540 PEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQK 589
>AK090429-1|BAC03410.1| 1799|Homo sapiens FLJ00346 protein protein.
Length = 1799
Score = 36.7 bits (81), Expect = 0.41
Identities = 29/110 (26%), Positives = 55/110 (50%), Gaps = 9/110 (8%)
Query: 322 DVIMPGDV-RNDLYLTLEKAEFERGGKSTAKNVLATVTVHDNTGQVISDC---VWGASGN 377
+V +P V RN LY+ ++ F ++A+N+ T+ + G+ S+ ++G S
Sbjct: 251 EVYVPHTVYRNLLYVYPQRLNFVNK-LASARNI--TIKIQFMCGEDASNAMPVIFGKSSG 307
Query: 378 GSTSYE--SLVLYHNNSPAWGEQLRLTVPLETFTHAHVRIEFRHCSTRDK 425
E + V YHN SP + E++++ +P + + H+ F H S + K
Sbjct: 308 PEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQK 357
>AB191037-1|BAE45254.1| 2099|Homo sapiens dedicator of cytokinesis 8
protein.
Length = 2099
Score = 36.7 bits (81), Expect = 0.41
Identities = 29/110 (26%), Positives = 55/110 (50%), Gaps = 9/110 (8%)
Query: 322 DVIMPGDV-RNDLYLTLEKAEFERGGKSTAKNVLATVTVHDNTGQVISDC---VWGASGN 377
+V +P V RN LY+ ++ F ++A+N+ T+ + G+ S+ ++G S
Sbjct: 551 EVYVPHTVYRNLLYVYPQRLNFVNK-LASARNI--TIKIQFMCGEDASNAMPVIFGKSSG 607
Query: 378 GSTSYE--SLVLYHNNSPAWGEQLRLTVPLETFTHAHVRIEFRHCSTRDK 425
E + V YHN SP + E++++ +P + + H+ F H S + K
Sbjct: 608 PEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQK 657
>AY692226-1|AAU04438.1| 2073|Homo sapiens Cdc42-associated guanine
nucleotide exchange factor ACG/DOCK11 protein.
Length = 2073
Score = 35.9 bits (79), Expect = 0.71
Identities = 55/250 (22%), Positives = 106/250 (42%), Gaps = 20/250 (8%)
Query: 350 AKNVLATVTVHDNTGQVIS--DCVWGASGNG--STSYESLVLYHNNSPAWGEQLRLTVPL 405
A+N+ V D+ S C++G +T+ ++V +HN +P + +++++ +P+
Sbjct: 661 ARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPI 720
Query: 406 ETFTHAHVRIEFRH--CSTRDKNERKLFGFAFARLMEASGATLRDGAHELHVYKCDDP-S 462
H+ F H C + K K + A L+DG + ++ P S
Sbjct: 721 HLHQKHHLLFTFYHVSCEIKTKGTTKKQDTVETPVGFAWVPLLKDG--RIITFEQQLPVS 778
Query: 463 KLLTASYLSLPSCANDAARAAPPNGVVPSFQRSSKENCTISTLLCSTKLTQNEDLLALLQ 522
L YL+L NDA N V + +K I + L ST TQ+ +
Sbjct: 779 ANLPPGYLNL----NDAESRRQCN-VDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFH 833
Query: 523 W----RAHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFS--TEDGNSTPHSG 576
++ ++V L++ L+ + + +I+FL +L LF + + T + + +
Sbjct: 834 HCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCT 893
Query: 577 TVFLVLISIC 586
V L ++S C
Sbjct: 894 MVLLHIVSKC 903
>AL391280-3|CAI41411.1| 2077|Homo sapiens dedicator of cytokinesis
11 protein.
Length = 2077
Score = 35.1 bits (77), Expect = 1.2
Identities = 55/250 (22%), Positives = 105/250 (42%), Gaps = 20/250 (8%)
Query: 350 AKNVLATVTVHDNTGQVIS--DCVWGASGNG--STSYESLVLYHNNSPAWGEQLRLTVPL 405
A+N+ V D+ S C++G +T+ ++V +HN +P + +++++ +P+
Sbjct: 661 ARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPI 720
Query: 406 ETFTHAHVRIEFRH--CSTRDKNERKLFGFAFARLMEASGATLRDGAHELHVYKCDDP-S 462
H+ F H C K K + A L+DG + ++ P S
Sbjct: 721 HLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDG--RIITFEQQLPVS 778
Query: 463 KLLTASYLSLPSCANDAARAAPPNGVVPSFQRSSKENCTISTLLCSTKLTQNEDLLALLQ 522
L YL+L NDA N V + +K I + L ST TQ+ +
Sbjct: 779 ANLPPGYLNL----NDAESRRQCN-VDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFH 833
Query: 523 W----RAHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFS--TEDGNSTPHSG 576
++ ++V L++ L+ + + +I+FL +L LF + + T + + +
Sbjct: 834 HCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCT 893
Query: 577 TVFLVLISIC 586
V L ++S C
Sbjct: 894 MVLLHIVSKC 903
>AL391237-2|CAI41407.1| 2077|Homo sapiens dedicator of cytokinesis
11 protein.
Length = 2077
Score = 35.1 bits (77), Expect = 1.2
Identities = 55/250 (22%), Positives = 105/250 (42%), Gaps = 20/250 (8%)
Query: 350 AKNVLATVTVHDNTGQVIS--DCVWGASGNG--STSYESLVLYHNNSPAWGEQLRLTVPL 405
A+N+ V D+ S C++G +T+ ++V +HN +P + +++++ +P+
Sbjct: 661 ARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPI 720
Query: 406 ETFTHAHVRIEFRH--CSTRDKNERKLFGFAFARLMEASGATLRDGAHELHVYKCDDP-S 462
H+ F H C K K + A L+DG + ++ P S
Sbjct: 721 HLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDG--RIITFEQQLPVS 778
Query: 463 KLLTASYLSLPSCANDAARAAPPNGVVPSFQRSSKENCTISTLLCSTKLTQNEDLLALLQ 522
L YL+L NDA N V + +K I + L ST TQ+ +
Sbjct: 779 ANLPPGYLNL----NDAESRRQCN-VDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFH 833
Query: 523 W----RAHPEKVQETLLRVLRLGDGLSCEELIKFLRDVLDALFALFS--TEDGNSTPHSG 576
++ ++V L++ L+ + + +I+FL +L LF + + T + + +
Sbjct: 834 HCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCT 893
Query: 577 TVFLVLISIC 586
V L ++S C
Sbjct: 894 MVLLHIVSKC 903
>AL161725-1|CAM13232.1| 1566|Homo sapiens dedicator of cytokinesis 8
protein.
Length = 1566
Score = 33.1 bits (72), Expect = 5.0
Identities = 13/40 (32%), Positives = 23/40 (57%)
Query: 386 VLYHNNSPAWGEQLRLTVPLETFTHAHVRIEFRHCSTRDK 425
V YHN SP + E++++ +P + + H+ F H S + K
Sbjct: 85 VTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQK 124
>AK074081-1|BAB84907.1| 1373|Homo sapiens FLJ00152 protein protein.
Length = 1373
Score = 33.1 bits (72), Expect = 5.0
Identities = 13/40 (32%), Positives = 23/40 (57%)
Query: 386 VLYHNNSPAWGEQLRLTVPLETFTHAHVRIEFRHCSTRDK 425
V YHN SP + E++++ +P + + H+ F H S + K
Sbjct: 28 VTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQK 67
>BC131527-1|AAI31528.1| 823|Homo sapiens MCTP2 protein protein.
Length = 823
Score = 32.7 bits (71), Expect = 6.6
Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 13/89 (14%)
Query: 377 NGSTSYESLVLYHNNSPAWGEQLRLTVPLETFTH-AHVRIEFRHCSTRDKNERKLFGFAF 435
NG T Y+S V+Y N +P W E + +P+++ V++ R +T D G AF
Sbjct: 224 NGKTLYKSKVIYKNLNPVWDE--IVVLPIQSLDQKLRVKVYDRDLTTSD-----FMGSAF 276
Query: 436 ARLMEASGATLRDGAHELHVYKCDDPSKL 464
L + L H+ K +DP+ L
Sbjct: 277 VILSD-----LELNRTTEHILKLEDPNSL 300
>BC011877-1|AAH11877.1| 350|Homo sapiens DOCK5 protein protein.
Length = 350
Score = 32.7 bits (71), Expect = 6.6
Identities = 46/208 (22%), Positives = 82/208 (39%), Gaps = 31/208 (14%)
Query: 66 LGLELVPRR-GAEAVEPEDISLVELYRVHVESAERAAAVRLRFYNFIIDIXXXXXXXXXX 124
LGL+LV R ++P++ S + L++ H E A + +++ I+
Sbjct: 159 LGLDLVVRDDNGNILDPDETSTIALFKAH-EVASKRIEEKIQEEKSILQNLDLRGQSIFS 217
Query: 125 XXXXXXXXXQSHHLMCSMRDFGHTAGGDEAELLLWLHDARRSQPLSERFRIRIARDGFSN 184
+ +C++ G++AEL + L+D +S +SE + IR +G
Sbjct: 218 TIHTYGLYVNFKNFVCNI--------GEDAELFMALYDPDQSTFISENYLIRWGSNGMPK 269
Query: 185 ------------YDLSTTDLTR-ELWLVAWVIRVXXXXXXXXXXXXXXXXXXPVARRPLG 231
DLS+ DL R + LV ++RV RRP G
Sbjct: 270 EIEKLNNLQAVFTDLSSMDLIRPRVSLVCQIVRVGHMELKEGKKHTCG------LRRPFG 323
Query: 232 AGVLSLADFLRQTGQHPAEKEYTFKVYQ 259
V+ + D + G+ E++ F +Q
Sbjct: 324 VAVMDITDIIH--GKVDDEEKQHFIPFQ 349
>AY656717-1|AAT73060.1| 878|Homo sapiens MCTP2 protein.
Length = 878
Score = 32.7 bits (71), Expect = 6.6
Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 13/89 (14%)
Query: 377 NGSTSYESLVLYHNNSPAWGEQLRLTVPLETFTH-AHVRIEFRHCSTRDKNERKLFGFAF 435
NG T Y+S V+Y N +P W E + +P+++ V++ R +T D G AF
Sbjct: 224 NGKTLYKSKVIYKNLNPVWDE--IVVLPIQSLDQKLRVKVYDRDLTTSD-----FMGSAF 276
Query: 436 ARLMEASGATLRDGAHELHVYKCDDPSKL 464
L + L H+ K +DP+ L
Sbjct: 277 VILSD-----LELNRTTEHILKLEDPNSL 300
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.323 0.135 0.413
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 136,689,452
Number of Sequences: 224733
Number of extensions: 5451421
Number of successful extensions: 9235
Number of sequences better than 10.0: 45
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 8988
Number of HSP's gapped (non-prelim): 87
length of query: 986
length of database: 73,234,838
effective HSP length: 97
effective length of query: 889
effective length of database: 51,435,737
effective search space: 45726370193
effective search space used: 45726370193
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 70 (32.3 bits)
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