Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000239-TA|BGIBMGA000239-PA|IPR002007|Haem peroxidase,
animal, IPR010255|Haem peroxidase
(429 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 113 1e-24
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 113 1e-24
BC132813-1|AAI32814.1| 515|Homo sapiens peroxidasin homolog (Dr... 113 1e-24
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 113 1e-24
AK131524-1|BAD18663.1| 515|Homo sapiens protein ( Homo sapiens ... 113 1e-24
AK058200-1|BAB71713.1| 494|Homo sapiens protein ( Homo sapiens ... 113 1e-24
J02969-1|AAA61215.1| 933|Homo sapiens TPO protein. 78 7e-14
DQ011222-1|AAY16985.1| 933|Homo sapiens thyroid peroxidase prot... 78 7e-14
AF439430-1|AAL74416.1| 760|Homo sapiens thyroid peroxidase prot... 78 7e-14
AB208960-1|BAD92197.1| 864|Homo sapiens thyroid peroxidase isof... 78 7e-14
Y00406-1|CAA68467.1| 933|Homo sapiens protein ( Human mRNA for ... 76 3e-13
M25715-1|AAA97517.1| 933|Homo sapiens TPO protein. 75 6e-13
M17755-1|AAA61217.2| 933|Homo sapiens thyroid peroxidase protein. 75 6e-13
BC095448-1|AAH95448.1| 933|Homo sapiens thyroid peroxidase prot... 75 6e-13
AC105450-1|AAX93261.1| 916|Homo sapiens unknown protein. 75 6e-13
U39573-1|AAC50717.1| 712|Homo sapiens salivary peroxidase protein. 70 1e-11
M58151-1|AAA63213.1| 324|Homo sapiens lactoperoxidase protein. 70 1e-11
BC107167-1|AAI07168.1| 712|Homo sapiens lactoperoxidase protein. 70 1e-11
BC107166-1|AAI07167.1| 712|Homo sapiens lactoperoxidase protein. 70 1e-11
AY324876-1|AAP72968.1| 712|Homo sapiens lactoperoxidase protein. 70 1e-11
M29913-1|AAA58458.1| 715|Homo sapiens eosinophil peroxidase pro... 70 2e-11
DQ054598-1|AAY43126.1| 715|Homo sapiens eosinophil peroxidase p... 70 2e-11
X15377-1|CAA33438.1| 745|Homo sapiens protein ( Human gene for ... 65 5e-10
X04876-2|CAA28565.1| 745|Homo sapiens prepro-myeloperoxidase pr... 65 5e-10
S56200-1|AAB25582.1| 745|Homo sapiens myeloperoxidase protein. 65 5e-10
M19507-1|AAA59863.1| 745|Homo sapiens myeloperoxidase protein. 65 5e-10
M17176-1|AAA60346.1| 745|Homo sapiens MPO protein. 65 5e-10
J02694-1|AAA59896.1| 745|Homo sapiens myeloperoxidase protein. 65 5e-10
DQ088846-1|AAY68218.1| 745|Homo sapiens myeloperoxidase protein. 65 5e-10
BC130476-1|AAI30477.1| 745|Homo sapiens myeloperoxidase protein. 65 5e-10
J02970-1|AAA61216.1| 876|Homo sapiens TPO protein. 63 2e-09
AF533531-1|AAN04474.1| 347|Homo sapiens thyroid peroxidase isof... 63 2e-09
AF533530-1|AAN04473.1| 350|Homo sapiens thyroid peroxidase isof... 63 2e-09
X14346-1|CAA32530.1| 702|Homo sapiens eosinophil preperoxidase ... 60 1e-08
X17358-1|CAA35235.1| 876|Homo sapiens protein ( Human mRNA from... 60 2e-08
BC114938-1|AAI14939.1| 1551|Homo sapiens dual oxidase 1 protein. 52 4e-06
BC114628-1|AAI14629.1| 1551|Homo sapiens dual oxidase 1 protein. 52 4e-06
AF230495-1|AAF73921.1| 1551|Homo sapiens NADPH thyroid oxidase 1... 52 4e-06
AF213465-1|AAF71295.1| 1551|Homo sapiens dual oxidase protein. 52 4e-06
AF267981-1|AAF78954.1| 1548|Homo sapiens putative NADPH oxidase/... 47 1e-04
AF230496-1|AAF73922.1| 1548|Homo sapiens NADPH thyroid oxidase 2... 47 1e-04
AF181972-1|AAF20055.1| 1210|Homo sapiens NADH/NADPH thyroid oxid... 47 1e-04
AK128591-1|BAC87516.1| 612|Homo sapiens protein ( Homo sapiens ... 45 6e-04
BC009496-1|AAH09496.2| 218|Homo sapiens PXDN protein protein. 44 0.001
BX538344-1|CAD98107.1| 95|Homo sapiens hypothetical protein pr... 36 0.21
AF533529-1|AAN04472.1| 140|Homo sapiens thyroid peroxidase isof... 35 0.48
M55702-2|AAA61218.1| 264|Homo sapiens thyroperoxidase protein. 33 1.9
M55702-1|AAA61219.1| 260|Homo sapiens thyroperoxidase protein. 33 1.9
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 113 bits (272), Expect = 1e-24
Identities = 59/167 (35%), Positives = 99/167 (59%), Gaps = 6/167 (3%)
Query: 262 DIPTTDLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQ-LKQVYETAED 320
D+ ++ +GR G+P Y YR +C+ S H F+DL + I + +I++ LK++Y + +
Sbjct: 1170 DLAAINIQRGRDHGIPPYHDYRVYCN-LSAAHT-FEDLKNEIKNPEIREKLKRLYGSTLN 1227
Query: 321 IELMAGIWVENVIEGAQVPPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRK 380
I+L + VE+++ G+++ PT+ CLLS Q KR DR WYE P F+ QL +I++
Sbjct: 1228 IDLFPALVVEDLVPGSRLGPTLMCLLSTQFKRLRDGDRLWYENPG---VFSPAQLTQIKQ 1284
Query: 381 ASLALLLCYVGDDVEKIQPKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
SLA +LC D++ ++Q F + + SCDEIP +D W++
Sbjct: 1285 TSLARILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQD 1331
Score = 38.3 bits (85), Expect = 0.052
Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 7/96 (7%)
Query: 54 CDETEWRRTDGSCNNLYYPTRGAYHTPTFRILPADFREDF------EPRLTSSGKEYPLA 107
C ++R DG+CNNL +P GA T R+L + + F P +G P+
Sbjct: 753 CFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKSVYENGFNTPRGINPHRLYNGHALPMP 812
Query: 108 RHIKNNLL-TIGLATDAKLTQLSAYYIEFMAIDVVS 142
R + L+ T + D + T + + +F+ D+ S
Sbjct: 813 RLVSTTLIGTETVTPDEQFTHMLMQWGQFLDHDLDS 848
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated antigen
MG50 protein.
Length = 1496
Score = 113 bits (272), Expect = 1e-24
Identities = 59/167 (35%), Positives = 99/167 (59%), Gaps = 6/167 (3%)
Query: 262 DIPTTDLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQ-LKQVYETAED 320
D+ ++ +GR G+P Y YR +C+ S H F+DL + I + +I++ LK++Y + +
Sbjct: 1170 DLAAINIQRGRDHGIPPYHDYRVYCN-LSAAHT-FEDLKNEIKNPEIREKLKRLYGSTLN 1227
Query: 321 IELMAGIWVENVIEGAQVPPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRK 380
I+L + VE+++ G+++ PT+ CLLS Q KR DR WYE P F+ QL +I++
Sbjct: 1228 IDLFPALVVEDLVPGSRLGPTLMCLLSTQFKRLRDGDRLWYENPG---VFSPAQLTQIKQ 1284
Query: 381 ASLALLLCYVGDDVEKIQPKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
SLA +LC D++ ++Q F + + SCDEIP +D W++
Sbjct: 1285 TSLARILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQD 1331
Score = 38.3 bits (85), Expect = 0.052
Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 7/96 (7%)
Query: 54 CDETEWRRTDGSCNNLYYPTRGAYHTPTFRILPADFREDF------EPRLTSSGKEYPLA 107
C ++R DG+CNNL +P GA T R+L + + F P +G P+
Sbjct: 753 CFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKSVYENGFNTPRGINPHRLYNGHALPMP 812
Query: 108 RHIKNNLL-TIGLATDAKLTQLSAYYIEFMAIDVVS 142
R + L+ T + D + T + + +F+ D+ S
Sbjct: 813 RLVSTTLIGTETVTPDEQFTHMLMQWGQFLDHDLDS 848
>BC132813-1|AAI32814.1| 515|Homo sapiens peroxidasin homolog
(Drosophila)-like protein.
Length = 515
Score = 113 bits (271), Expect = 1e-24
Identities = 59/167 (35%), Positives = 96/167 (57%), Gaps = 6/167 (3%)
Query: 262 DIPTTDLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQ-LKQVYETAED 320
D T + +GR G+P Y +R FC+ S K+ F+DL + I D +I+Q L+++Y + D
Sbjct: 335 DSAATIIQRGRDHGIPPYVDFRVFCNLTSVKN--FEDLQNEIKDSEIRQKLRKLYGSPGD 392
Query: 321 IELMAGIWVENVIEGAQVPPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRK 380
I+L + VE++I G +V PT+ CL Q +R DR WYE P F QL ++++
Sbjct: 393 IDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPG---VFTPAQLTQLKQ 449
Query: 381 ASLALLLCYVGDDVEKIQPKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
ASL+ +LC GD ++++Q F + ++C EIP +D W++
Sbjct: 450 ASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQD 496
>AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase protein.
Length = 1463
Score = 113 bits (271), Expect = 1e-24
Identities = 59/167 (35%), Positives = 96/167 (57%), Gaps = 6/167 (3%)
Query: 262 DIPTTDLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQ-LKQVYETAED 320
D T + +GR G+P Y +R FC+ S K+ F+DL + I D +I+Q L+++Y + D
Sbjct: 1136 DSAATIIQRGRDHGIPPYVDFRVFCNLTSVKN--FEDLQNEIKDSEIRQKLRKLYGSPGD 1193
Query: 321 IELMAGIWVENVIEGAQVPPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRK 380
I+L + VE++I G +V PT+ CL Q +R DR WYE P F QL ++++
Sbjct: 1194 IDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPG---VFTPAQLTQLKQ 1250
Query: 381 ASLALLLCYVGDDVEKIQPKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
ASL+ +LC GD ++++Q F + ++C EIP +D W++
Sbjct: 1251 ASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQD 1297
Score = 37.1 bits (82), Expect = 0.12
Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 44 LSTCANNIQPCDETEWRRTDGSCNNLYYPTRGAYHTPTFRILPADFRE 91
L C+N C ++R DG+CNNL PT GA T R+L +R+
Sbjct: 715 LPNCSNR---CFHAKYRAHDGTCNNLQQPTWGAALTAFARLLQPAYRD 759
>AK131524-1|BAD18663.1| 515|Homo sapiens protein ( Homo sapiens
cDNA FLJ43518 fis, clone PERIC2009086, moderately
similar to Homo sapiens melanoma-associated antigen MG50
mRNA. ).
Length = 515
Score = 113 bits (271), Expect = 1e-24
Identities = 59/167 (35%), Positives = 96/167 (57%), Gaps = 6/167 (3%)
Query: 262 DIPTTDLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQ-LKQVYETAED 320
D T + +GR G+P Y +R FC+ S K+ F+DL + I D +I+Q L+++Y + D
Sbjct: 335 DSAATIIQRGRDHGIPPYVDFRVFCNLTSVKN--FEDLQNEIKDSEIRQKLRKLYGSPGD 392
Query: 321 IELMAGIWVENVIEGAQVPPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRK 380
I+L + VE++I G +V PT+ CL Q +R DR WYE P F QL ++++
Sbjct: 393 IDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPG---VFTPAQLTQLKQ 449
Query: 381 ASLALLLCYVGDDVEKIQPKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
ASL+ +LC GD ++++Q F + ++C EIP +D W++
Sbjct: 450 ASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQD 496
>AK058200-1|BAB71713.1| 494|Homo sapiens protein ( Homo sapiens
cDNA FLJ25471 fis, clone TST09553. ).
Length = 494
Score = 113 bits (271), Expect = 1e-24
Identities = 59/167 (35%), Positives = 96/167 (57%), Gaps = 6/167 (3%)
Query: 262 DIPTTDLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQ-LKQVYETAED 320
D T + +GR G+P Y +R FC+ S K+ F+DL + I D +I+Q L+++Y + D
Sbjct: 167 DSAATIIQRGRDHGIPPYVDFRVFCNLTSVKN--FEDLQNEIKDSEIRQKLRKLYGSPGD 224
Query: 321 IELMAGIWVENVIEGAQVPPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRK 380
I+L + VE++I G +V PT+ CL Q +R DR WYE P F QL ++++
Sbjct: 225 IDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPG---VFTPAQLTQLKQ 281
Query: 381 ASLALLLCYVGDDVEKIQPKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
ASL+ +LC GD ++++Q F + ++C EIP +D W++
Sbjct: 282 ASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQD 328
>J02969-1|AAA61215.1| 933|Homo sapiens TPO protein.
Length = 933
Score = 77.8 bits (183), Expect = 7e-14
Identities = 46/166 (27%), Positives = 80/166 (48%), Gaps = 5/166 (3%)
Query: 262 DIPTTDLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQLKQVYETAEDI 321
D+ + +L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I
Sbjct: 574 DLASINLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNI 632
Query: 322 ELMAGIWVENVIEGAQVPPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKA 381
++ G EN + A+ P CL+ Q+K D W+E H F Q +E+ K
Sbjct: 633 DVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWE---NSHVFTDAQRRELEKH 689
Query: 382 SLALLLCYVGDDVEKIQPKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
SL+ ++C + ++ AF + + SCD IP ++ W+E
Sbjct: 690 SLSRVIC-DNTGLTRVPMDAFQVGKFPEDFESCDSIPGMNLEAWRE 734
>DQ011222-1|AAY16985.1| 933|Homo sapiens thyroid peroxidase
protein.
Length = 933
Score = 77.8 bits (183), Expect = 7e-14
Identities = 46/166 (27%), Positives = 80/166 (48%), Gaps = 5/166 (3%)
Query: 262 DIPTTDLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQLKQVYETAEDI 321
D+ + +L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I
Sbjct: 574 DLASINLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNI 632
Query: 322 ELMAGIWVENVIEGAQVPPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKA 381
++ G EN + A+ P CL+ Q+K D W+E H F Q +E+ K
Sbjct: 633 DVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWE---NSHVFTDAQRRELEKH 689
Query: 382 SLALLLCYVGDDVEKIQPKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
SL+ ++C + ++ AF + + SCD IP ++ W+E
Sbjct: 690 SLSRVIC-DNTGLTRVPMDAFQVGKFPEDFESCDSIPGMNLEAWRE 734
>AF439430-1|AAL74416.1| 760|Homo sapiens thyroid peroxidase
protein.
Length = 760
Score = 77.8 bits (183), Expect = 7e-14
Identities = 46/166 (27%), Positives = 80/166 (48%), Gaps = 5/166 (3%)
Query: 262 DIPTTDLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQLKQVYETAEDI 321
D+ + +L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I
Sbjct: 401 DLASINLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNI 459
Query: 322 ELMAGIWVENVIEGAQVPPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKA 381
++ G EN + A+ P CL+ Q+K D W+E H F Q +E+ K
Sbjct: 460 DVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWE---NSHVFTDAQRRELEKH 516
Query: 382 SLALLLCYVGDDVEKIQPKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
SL+ ++C + ++ AF + + SCD IP ++ W+E
Sbjct: 517 SLSRVIC-DNTGLTRVPMDAFQVGKFPEDFESCDSIPGMNLEAWRE 561
>AB208960-1|BAD92197.1| 864|Homo sapiens thyroid peroxidase isoform
d variant protein.
Length = 864
Score = 77.8 bits (183), Expect = 7e-14
Identities = 46/166 (27%), Positives = 80/166 (48%), Gaps = 5/166 (3%)
Query: 262 DIPTTDLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQLKQVYETAEDI 321
D+ + +L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I
Sbjct: 503 DLASINLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNI 561
Query: 322 ELMAGIWVENVIEGAQVPPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKA 381
++ G EN + A+ P CL+ Q+K D W+E H F Q +E+ K
Sbjct: 562 DVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWE---NSHVFTDAQRRELEKH 618
Query: 382 SLALLLCYVGDDVEKIQPKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
SL+ ++C + ++ AF + + SCD IP ++ W+E
Sbjct: 619 SLSRVIC-DNTGLTRVPMDAFQVGKFPEDFESCDSIPGMNLEAWRE 663
>Y00406-1|CAA68467.1| 933|Homo sapiens protein ( Human mRNA for
thyroperoxidase. ).
Length = 933
Score = 75.8 bits (178), Expect = 3e-13
Identities = 45/166 (27%), Positives = 80/166 (48%), Gaps = 5/166 (3%)
Query: 262 DIPTTDLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQLKQVYETAEDI 321
++ + +L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I
Sbjct: 574 NLASINLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNI 632
Query: 322 ELMAGIWVENVIEGAQVPPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKA 381
++ G EN + A+ P CL+ Q+K D W+E H F Q +E+ K
Sbjct: 633 DVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWE---NSHVFTDAQRRELEKH 689
Query: 382 SLALLLCYVGDDVEKIQPKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
SL+ ++C + ++ AF + + SCD IP ++ W+E
Sbjct: 690 SLSRVIC-DNTGLTRVPMDAFQVGKFPEDFESCDSIPGMNLEAWRE 734
>M25715-1|AAA97517.1| 933|Homo sapiens TPO protein.
Length = 933
Score = 74.5 bits (175), Expect = 6e-13
Identities = 45/166 (27%), Positives = 79/166 (47%), Gaps = 5/166 (3%)
Query: 262 DIPTTDLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQLKQVYETAEDI 321
D+ + +L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I
Sbjct: 574 DLASINLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNI 632
Query: 322 ELMAGIWVENVIEGAQVPPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKA 381
++ G EN + A+ P CL+ Q+K D W+E H F Q +E+ K
Sbjct: 633 DVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWE---NSHVFTDAQRRELEKH 689
Query: 382 SLALLLCYVGDDVEKIQPKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
SL+ ++C + ++ AF + + SCD I ++ W+E
Sbjct: 690 SLSRVIC-DNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRE 734
>M17755-1|AAA61217.2| 933|Homo sapiens thyroid peroxidase protein.
Length = 933
Score = 74.5 bits (175), Expect = 6e-13
Identities = 45/166 (27%), Positives = 79/166 (47%), Gaps = 5/166 (3%)
Query: 262 DIPTTDLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQLKQVYETAEDI 321
D+ + +L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I
Sbjct: 574 DLASINLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNI 632
Query: 322 ELMAGIWVENVIEGAQVPPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKA 381
++ G EN + A+ P CL+ Q+K D W+E H F Q +E+ K
Sbjct: 633 DVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWE---NSHVFTDAQRRELEKH 689
Query: 382 SLALLLCYVGDDVEKIQPKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
SL+ ++C + ++ AF + + SCD I ++ W+E
Sbjct: 690 SLSRVIC-DNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRE 734
>BC095448-1|AAH95448.1| 933|Homo sapiens thyroid peroxidase
protein.
Length = 933
Score = 74.5 bits (175), Expect = 6e-13
Identities = 45/166 (27%), Positives = 79/166 (47%), Gaps = 5/166 (3%)
Query: 262 DIPTTDLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQLKQVYETAEDI 321
D+ + +L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I
Sbjct: 574 DLASINLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNI 632
Query: 322 ELMAGIWVENVIEGAQVPPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKA 381
++ G EN + A+ P CL+ Q+K D W+E H F Q +E+ K
Sbjct: 633 DVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWE---NSHVFTDAQRRELEKH 689
Query: 382 SLALLLCYVGDDVEKIQPKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
SL+ ++C + ++ AF + + SCD I ++ W+E
Sbjct: 690 SLSRVIC-DNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRE 734
>AC105450-1|AAX93261.1| 916|Homo sapiens unknown protein.
Length = 916
Score = 74.5 bits (175), Expect = 6e-13
Identities = 45/166 (27%), Positives = 79/166 (47%), Gaps = 5/166 (3%)
Query: 262 DIPTTDLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQLKQVYETAEDI 321
D+ + +L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I
Sbjct: 574 DLASINLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNI 632
Query: 322 ELMAGIWVENVIEGAQVPPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKA 381
++ G EN + A+ P CL+ Q+K D W+E H F Q +E+ K
Sbjct: 633 DVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWE---NSHVFTDAQRRELEKH 689
Query: 382 SLALLLCYVGDDVEKIQPKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
SL+ ++C + ++ AF + + SCD I ++ W+E
Sbjct: 690 SLSRVIC-DNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRE 734
>U39573-1|AAC50717.1| 712|Homo sapiens salivary peroxidase protein.
Length = 712
Score = 70.1 bits (164), Expect = 1e-11
Identities = 58/266 (21%), Positives = 115/266 (43%), Gaps = 14/266 (5%)
Query: 168 YDETVVPQIALEYAYASRWFHTIQYGAQKLFDKNFNLI---KEVPMVNFSLSVQSLAIGD 224
Y E+V P+I+ + +A R+ H + D+N+ E+P+ + +
Sbjct: 448 YSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDG 507
Query: 225 IMSTVTRGSYYQATG--KADSTVDPDISDIGLGPVQEV--FDIPTTDLAKGRYFGLPSYT 280
+ + RG + + K + + ++ + P + FD+ + + R G P Y
Sbjct: 508 GIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYN 567
Query: 281 KYRDFCSGYSKKHVDFDDLTDHISDEKI-QQLKQVYETAEDIELMAGIWVENVIEGAQVP 339
+R FC + ++L + + + ++L +Y T ++I++ G E ++E +V
Sbjct: 568 SWRAFCD--LSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVG 625
Query: 340 PTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQP 399
P + CLL Q ++ DR W+E P F +EQ ++K S + L+C + K+
Sbjct: 626 PLLACLLGKQFQQIRDGDRFWWENPG---VFTNEQKDSLQKMSFSRLVC-DNTRITKVPR 681
Query: 400 KAFTIVGKGNNLVSCDEIPAIDFTHW 425
F + V C I +D + W
Sbjct: 682 DPFWANSYPYDFVDCSAIDKLDLSPW 707
Score = 36.3 bits (80), Expect = 0.21
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 7/69 (10%)
Query: 54 CDE-TEWRRTDGSCNNLYYPTRGAYHTPTFRILPADFRE------DFEPRLTSSGKEYPL 106
CD + +R G CNN P GA + R LPA++ + + P T +G PL
Sbjct: 132 CDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPL 191
Query: 107 ARHIKNNLL 115
AR + N ++
Sbjct: 192 AREVSNKIV 200
>M58151-1|AAA63213.1| 324|Homo sapiens lactoperoxidase protein.
Length = 324
Score = 70.1 bits (164), Expect = 1e-11
Identities = 58/266 (21%), Positives = 115/266 (43%), Gaps = 14/266 (5%)
Query: 168 YDETVVPQIALEYAYASRWFHTIQYGAQKLFDKNFNLI---KEVPMVNFSLSVQSLAIGD 224
Y E+V P+I+ + +A R+ H + D+N+ E+P+ + +
Sbjct: 60 YSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDG 119
Query: 225 IMSTVTRGSYYQATG--KADSTVDPDISDIGLGPVQEV--FDIPTTDLAKGRYFGLPSYT 280
+ + RG + + K + + ++ + P + FD+ + + R G P Y
Sbjct: 120 GIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYN 179
Query: 281 KYRDFCSGYSKKHVDFDDLTDHISDEKI-QQLKQVYETAEDIELMAGIWVENVIEGAQVP 339
+R FC + ++L + + + ++L +Y T ++I++ G E ++E +V
Sbjct: 180 SWRAFCD--LSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVG 237
Query: 340 PTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQP 399
P + CLL Q ++ DR W+E P F +EQ ++K S + L+C + K+
Sbjct: 238 PLLACLLGKQFQQIRDGDRFWWENPG---VFTNEQKDSLQKMSFSRLVC-DNTRITKVPR 293
Query: 400 KAFTIVGKGNNLVSCDEIPAIDFTHW 425
F + V C I +D + W
Sbjct: 294 DPFWANSYPYDFVDCSAIDKLDLSPW 319
>BC107167-1|AAI07168.1| 712|Homo sapiens lactoperoxidase protein.
Length = 712
Score = 70.1 bits (164), Expect = 1e-11
Identities = 58/266 (21%), Positives = 115/266 (43%), Gaps = 14/266 (5%)
Query: 168 YDETVVPQIALEYAYASRWFHTIQYGAQKLFDKNFNLI---KEVPMVNFSLSVQSLAIGD 224
Y E+V P+I+ + +A R+ H + D+N+ E+P+ + +
Sbjct: 448 YSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDG 507
Query: 225 IMSTVTRGSYYQATG--KADSTVDPDISDIGLGPVQEV--FDIPTTDLAKGRYFGLPSYT 280
+ + RG + + K + + ++ + P + FD+ + + R G P Y
Sbjct: 508 GIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYN 567
Query: 281 KYRDFCSGYSKKHVDFDDLTDHISDEKI-QQLKQVYETAEDIELMAGIWVENVIEGAQVP 339
+R FC + ++L + + + ++L +Y T ++I++ G E ++E +V
Sbjct: 568 SWRAFCD--LSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVG 625
Query: 340 PTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQP 399
P + CLL Q ++ DR W+E P F +EQ ++K S + L+C + K+
Sbjct: 626 PLLACLLGKQFQQIRDGDRFWWENPG---VFTNEQKDSLQKMSFSRLVC-DNTRITKVPR 681
Query: 400 KAFTIVGKGNNLVSCDEIPAIDFTHW 425
F + V C I +D + W
Sbjct: 682 DPFWANSYPYDFVDCSAIDKLDLSPW 707
Score = 36.3 bits (80), Expect = 0.21
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 7/69 (10%)
Query: 54 CDE-TEWRRTDGSCNNLYYPTRGAYHTPTFRILPADFRE------DFEPRLTSSGKEYPL 106
CD + +R G CNN P GA + R LPA++ + + P T +G PL
Sbjct: 132 CDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPL 191
Query: 107 ARHIKNNLL 115
AR + N ++
Sbjct: 192 AREVSNKIV 200
>BC107166-1|AAI07167.1| 712|Homo sapiens lactoperoxidase protein.
Length = 712
Score = 70.1 bits (164), Expect = 1e-11
Identities = 58/266 (21%), Positives = 115/266 (43%), Gaps = 14/266 (5%)
Query: 168 YDETVVPQIALEYAYASRWFHTIQYGAQKLFDKNFNLI---KEVPMVNFSLSVQSLAIGD 224
Y E+V P+I+ + +A R+ H + D+N+ E+P+ + +
Sbjct: 448 YSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDG 507
Query: 225 IMSTVTRGSYYQATG--KADSTVDPDISDIGLGPVQEV--FDIPTTDLAKGRYFGLPSYT 280
+ + RG + + K + + ++ + P + FD+ + + R G P Y
Sbjct: 508 GIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYN 567
Query: 281 KYRDFCSGYSKKHVDFDDLTDHISDEKI-QQLKQVYETAEDIELMAGIWVENVIEGAQVP 339
+R FC + ++L + + + ++L +Y T ++I++ G E ++E +V
Sbjct: 568 SWRAFCD--LSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVG 625
Query: 340 PTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQP 399
P + CLL Q ++ DR W+E P F +EQ ++K S + L+C + K+
Sbjct: 626 PLLACLLGKQFQQIRDGDRFWWENPG---VFTNEQKDSLQKMSFSRLVC-DNTRITKVPR 681
Query: 400 KAFTIVGKGNNLVSCDEIPAIDFTHW 425
F + V C I +D + W
Sbjct: 682 DPFWANSYPYDFVDCSAIDKLDLSPW 707
Score = 36.3 bits (80), Expect = 0.21
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 7/69 (10%)
Query: 54 CDE-TEWRRTDGSCNNLYYPTRGAYHTPTFRILPADFRE------DFEPRLTSSGKEYPL 106
CD + +R G CNN P GA + R LPA++ + + P T +G PL
Sbjct: 132 CDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPL 191
Query: 107 ARHIKNNLL 115
AR + N ++
Sbjct: 192 AREVSNKIV 200
>AY324876-1|AAP72968.1| 712|Homo sapiens lactoperoxidase protein.
Length = 712
Score = 70.1 bits (164), Expect = 1e-11
Identities = 58/266 (21%), Positives = 115/266 (43%), Gaps = 14/266 (5%)
Query: 168 YDETVVPQIALEYAYASRWFHTIQYGAQKLFDKNFNLI---KEVPMVNFSLSVQSLAIGD 224
Y E+V P+I+ + +A R+ H + D+N+ E+P+ + +
Sbjct: 448 YSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDG 507
Query: 225 IMSTVTRGSYYQATG--KADSTVDPDISDIGLGPVQEV--FDIPTTDLAKGRYFGLPSYT 280
+ + RG + + K + + ++ + P + FD+ + + R G P Y
Sbjct: 508 GIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYN 567
Query: 281 KYRDFCSGYSKKHVDFDDLTDHISDEKI-QQLKQVYETAEDIELMAGIWVENVIEGAQVP 339
+R FC + ++L + + + ++L +Y T ++I++ G E ++E +V
Sbjct: 568 SWRAFCD--LSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVG 625
Query: 340 PTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQP 399
P + CLL Q ++ DR W+E P F +EQ ++K S + L+C + K+
Sbjct: 626 PLLACLLGKQFQQIRDGDRFWWENPG---VFTNEQKDSLQKMSFSRLVC-DNTRITKVPR 681
Query: 400 KAFTIVGKGNNLVSCDEIPAIDFTHW 425
F + V C I +D + W
Sbjct: 682 DPFWANSYPYDFVDCSAIDKLDLSPW 707
Score = 36.3 bits (80), Expect = 0.21
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 7/69 (10%)
Query: 54 CDE-TEWRRTDGSCNNLYYPTRGAYHTPTFRILPADFRE------DFEPRLTSSGKEYPL 106
CD + +R G CNN P GA + R LPA++ + + P T +G PL
Sbjct: 132 CDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPL 191
Query: 107 ARHIKNNLL 115
AR + N ++
Sbjct: 192 AREVSNKIV 200
>M29913-1|AAA58458.1| 715|Homo sapiens eosinophil peroxidase
protein.
Length = 715
Score = 69.7 bits (163), Expect = 2e-11
Identities = 56/266 (21%), Positives = 116/266 (43%), Gaps = 13/266 (4%)
Query: 168 YDETVVPQIALEYAYASRWFHTIQYGAQKLFDKNFNLI---KEVPMVNFSLSVQSLAIGD 224
Y V P++A + A R+ HT+ D + VP+ + + +
Sbjct: 454 YCSNVDPRVANVFTLAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLSSAFFASWRIVYEG 513
Query: 225 IMSTVTRGSYYQAT--GKADSTVDPDISDIGLGPVQEV-FDIPTTDLAKGRYFGLPSYTK 281
+ + RG + D+ + ++ D V+ + D+ ++ + R GLP Y
Sbjct: 514 GIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQVRRIGLDLAALNMQRSRDHGLPGYNA 573
Query: 282 YRDFCSGYSKKHVDFDDLTDHISDEKI-QQLKQVYETAEDIELMAGIWVENVIEGAQVPP 340
+R FC G S+ + L+ + ++ + ++ +Y T ++I++ G E ++ GA+V P
Sbjct: 574 WRRFC-GLSQPR-NLAQLSRVLKNQDLARKFLNLYGTPDNIDIWIGAIAEPLLPGARVGP 631
Query: 341 TVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQPK 400
+ CL NQ +R+ DR W+++ F Q + + + SL+ ++C + +
Sbjct: 632 LLACLFENQFRRARDGDRFWWQKRG---VFTKRQRKALSRISLSRIIC-DNTGITTVSRD 687
Query: 401 AFTIVGKGNNLVSCDEIPAIDFTHWK 426
F V+C IP ++ + W+
Sbjct: 688 IFRANIYPRGFVNCSRIPRLNLSAWR 713
Score = 31.5 bits (68), Expect = 5.9
Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 12/95 (12%)
Query: 29 LLTDEQRQAYEKANILSTCA--NNIQPCDETEWRRTDGSCNNLYYPTRGAYHTPTFRILP 86
+LT+ Q + +A S CA + + C + ++R G CNN P GA + R LP
Sbjct: 117 VLTEPQLRLLSQA---SGCALRDQAERCSD-KYRTITGRCNNKRRPLLGASNQALARWLP 172
Query: 87 ADFRE------DFEPRLTSSGKEYPLARHIKNNLL 115
A++ + + P +G PL R + N ++
Sbjct: 173 AEYEDGLSLPFGWTPSRRRNGFLLPLVRAVSNQIV 207
>DQ054598-1|AAY43126.1| 715|Homo sapiens eosinophil peroxidase
protein.
Length = 715
Score = 69.7 bits (163), Expect = 2e-11
Identities = 56/266 (21%), Positives = 116/266 (43%), Gaps = 13/266 (4%)
Query: 168 YDETVVPQIALEYAYASRWFHTIQYGAQKLFDKNFNLI---KEVPMVNFSLSVQSLAIGD 224
Y V P++A + A R+ HT+ D + VP+ + + +
Sbjct: 454 YCSNVDPRVANVFTLAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLSSAFFASWRIVYEG 513
Query: 225 IMSTVTRGSYYQAT--GKADSTVDPDISDIGLGPVQEV-FDIPTTDLAKGRYFGLPSYTK 281
+ + RG + D+ + ++ D V+ + D+ ++ + R GLP Y
Sbjct: 514 GIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQVRRIGLDLAALNMQRSRDHGLPGYNA 573
Query: 282 YRDFCSGYSKKHVDFDDLTDHISDEKI-QQLKQVYETAEDIELMAGIWVENVIEGAQVPP 340
+R FC G S+ + L+ + ++ + ++ +Y T ++I++ G E ++ GA+V P
Sbjct: 574 WRRFC-GLSQPR-NLAQLSRVLKNQDLARKFLNLYGTPDNIDIWIGAIAEPLLPGARVGP 631
Query: 341 TVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQPK 400
+ CL NQ +R+ DR W+++ F Q + + + SL+ ++C + +
Sbjct: 632 LLACLFENQFRRARDGDRFWWQKRG---VFTKRQRKALSRISLSRIIC-DNTGITTVSRD 687
Query: 401 AFTIVGKGNNLVSCDEIPAIDFTHWK 426
F V+C IP ++ + W+
Sbjct: 688 IFRANIYPRGFVNCSRIPRLNLSAWR 713
Score = 31.5 bits (68), Expect = 5.9
Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 12/95 (12%)
Query: 29 LLTDEQRQAYEKANILSTCA--NNIQPCDETEWRRTDGSCNNLYYPTRGAYHTPTFRILP 86
+LT+ Q + +A S CA + + C + ++R G CNN P GA + R LP
Sbjct: 117 VLTEPQLRLLSQA---SGCALRDQAERCSD-KYRTITGRCNNKRRPLLGASNQALARWLP 172
Query: 87 ADFRE------DFEPRLTSSGKEYPLARHIKNNLL 115
A++ + + P +G PL R + N ++
Sbjct: 173 AEYEDGLSLPFGWTPSRRRNGFLLPLVRAVSNQIV 207
>X15377-1|CAA33438.1| 745|Homo sapiens protein ( Human gene for the
light and heavy chains of myeloperoxidase. ).
Length = 745
Score = 64.9 bits (151), Expect = 5e-10
Identities = 58/269 (21%), Positives = 114/269 (42%), Gaps = 12/269 (4%)
Query: 168 YDETVVPQIALEYAYASRWFHTIQYGAQKLFDKNFNLIKEVPMVNFS---LSVQSLAIGD 224
Y+++V P+IA + A R+ HT+ D + ++ P V S + + +
Sbjct: 482 YNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEG 541
Query: 225 IMSTVTRGSYYQAT--GKADSTVDPDISDIGLGPVQEV-FDIPTTDLAKGRYFGLPSYTK 281
+ + RG + + +I + V + D+P ++ + R GLP Y
Sbjct: 542 GIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNA 601
Query: 282 YRDFCSGYSKKHVDFDDLTDHISDEKI-QQLKQVYETAEDIELMAGIWVENVIEGAQVPP 340
+R FC + V L + + K+ ++L + Y T +I++ G E + +V P
Sbjct: 602 WRRFCGLPQPETVG--QLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGP 659
Query: 341 TVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQPK 400
+ C++ Q ++ DR W+E F+ +Q Q + + SL ++C +
Sbjct: 660 LLACIIGTQFRKLRDGDRFWWENEG---VFSMQQRQALAQISLPRIICDNTGITTVSKNN 716
Query: 401 AFTIVGKGNNLVSCDEIPAIDFTHWKEES 429
F + V+C +PA++ W+E S
Sbjct: 717 IFMSNSYPRDFVNCSTLPALNLASWREAS 745
Score = 36.7 bits (81), Expect = 0.16
Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 9/98 (9%)
Query: 55 DETEWRRTDGSCNNLYYPTRGAYHTPTFRILPADFREDFE------PRLTSSGKEYPLAR 108
++ ++R G CNN PT GA + R LPA++ + F P + +G LAR
Sbjct: 169 EQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALAR 228
Query: 109 HIKNNLLTIGLATDAKLTQLSAYYIEFMAIDVVSAHDI 146
+ N + + TD +LT + FM + HD+
Sbjct: 229 AVSNEI--VRFPTD-QLTPDQERSLMFMQWGQLLDHDL 263
>X04876-2|CAA28565.1| 745|Homo sapiens prepro-myeloperoxidase
protein.
Length = 745
Score = 64.9 bits (151), Expect = 5e-10
Identities = 58/269 (21%), Positives = 114/269 (42%), Gaps = 12/269 (4%)
Query: 168 YDETVVPQIALEYAYASRWFHTIQYGAQKLFDKNFNLIKEVPMVNFS---LSVQSLAIGD 224
Y+++V P+IA + A R+ HT+ D + ++ P V S + + +
Sbjct: 482 YNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEG 541
Query: 225 IMSTVTRGSYYQAT--GKADSTVDPDISDIGLGPVQEV-FDIPTTDLAKGRYFGLPSYTK 281
+ + RG + + +I + V + D+P ++ + R GLP Y
Sbjct: 542 GIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNA 601
Query: 282 YRDFCSGYSKKHVDFDDLTDHISDEKI-QQLKQVYETAEDIELMAGIWVENVIEGAQVPP 340
+R FC + V L + + K+ ++L + Y T +I++ G E + +V P
Sbjct: 602 WRRFCGLPQPETVG--QLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGP 659
Query: 341 TVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQPK 400
+ C++ Q ++ DR W+E F+ +Q Q + + SL ++C +
Sbjct: 660 LLACIIGTQFRKLRDGDRFWWENEG---VFSMQQRQALAQISLPRIICDNTGITTVSKNN 716
Query: 401 AFTIVGKGNNLVSCDEIPAIDFTHWKEES 429
F + V+C +PA++ W+E S
Sbjct: 717 IFMSNSYPRDFVNCSTLPALNLASWREAS 745
Score = 36.7 bits (81), Expect = 0.16
Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 9/98 (9%)
Query: 55 DETEWRRTDGSCNNLYYPTRGAYHTPTFRILPADFREDFE------PRLTSSGKEYPLAR 108
++ ++R G CNN PT GA + R LPA++ + F P + +G LAR
Sbjct: 169 EQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALAR 228
Query: 109 HIKNNLLTIGLATDAKLTQLSAYYIEFMAIDVVSAHDI 146
+ N + + TD +LT + FM + HD+
Sbjct: 229 AVSNEI--VRFPTD-QLTPDQERSLMFMQWGQLLDHDL 263
>S56200-1|AAB25582.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 64.9 bits (151), Expect = 5e-10
Identities = 58/269 (21%), Positives = 114/269 (42%), Gaps = 12/269 (4%)
Query: 168 YDETVVPQIALEYAYASRWFHTIQYGAQKLFDKNFNLIKEVPMVNFS---LSVQSLAIGD 224
Y+++V P+IA + A R+ HT+ D + ++ P V S + + +
Sbjct: 482 YNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEG 541
Query: 225 IMSTVTRGSYYQAT--GKADSTVDPDISDIGLGPVQEV-FDIPTTDLAKGRYFGLPSYTK 281
+ + RG + + +I + V + D+P ++ + R GLP Y
Sbjct: 542 GIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNA 601
Query: 282 YRDFCSGYSKKHVDFDDLTDHISDEKI-QQLKQVYETAEDIELMAGIWVENVIEGAQVPP 340
+R FC + V L + + K+ ++L + Y T +I++ G E + +V P
Sbjct: 602 WRRFCGLPQPETVG--QLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGP 659
Query: 341 TVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQPK 400
+ C++ Q ++ DR W+E F+ +Q Q + + SL ++C +
Sbjct: 660 LLACIIGTQFRKLRDGDRFWWENEG---VFSMQQRQALAQISLPRIICDNTGITTVSKNN 716
Query: 401 AFTIVGKGNNLVSCDEIPAIDFTHWKEES 429
F + V+C +PA++ W+E S
Sbjct: 717 IFMSNSYPRDFVNCSTLPALNLASWREAS 745
Score = 36.7 bits (81), Expect = 0.16
Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 9/98 (9%)
Query: 55 DETEWRRTDGSCNNLYYPTRGAYHTPTFRILPADFREDFE------PRLTSSGKEYPLAR 108
++ ++R G CNN PT GA + R LPA++ + F P + +G LAR
Sbjct: 169 EQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALAR 228
Query: 109 HIKNNLLTIGLATDAKLTQLSAYYIEFMAIDVVSAHDI 146
+ N + + TD +LT + FM + HD+
Sbjct: 229 AVSNEI--VRFPTD-QLTPDQERSLMFMQWGQLLDHDL 263
>M19507-1|AAA59863.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 64.9 bits (151), Expect = 5e-10
Identities = 58/269 (21%), Positives = 114/269 (42%), Gaps = 12/269 (4%)
Query: 168 YDETVVPQIALEYAYASRWFHTIQYGAQKLFDKNFNLIKEVPMVNFS---LSVQSLAIGD 224
Y+++V P+IA + A R+ HT+ D + ++ P V S + + +
Sbjct: 482 YNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEG 541
Query: 225 IMSTVTRGSYYQAT--GKADSTVDPDISDIGLGPVQEV-FDIPTTDLAKGRYFGLPSYTK 281
+ + RG + + +I + V + D+P ++ + R GLP Y
Sbjct: 542 GIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNA 601
Query: 282 YRDFCSGYSKKHVDFDDLTDHISDEKI-QQLKQVYETAEDIELMAGIWVENVIEGAQVPP 340
+R FC + V L + + K+ ++L + Y T +I++ G E + +V P
Sbjct: 602 WRRFCGLPQPETVG--QLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGP 659
Query: 341 TVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQPK 400
+ C++ Q ++ DR W+E F+ +Q Q + + SL ++C +
Sbjct: 660 LLACIIGTQFRKLRDGDRFWWENEG---VFSMQQRQALAQISLPRIICDNTGITTVSKNN 716
Query: 401 AFTIVGKGNNLVSCDEIPAIDFTHWKEES 429
F + V+C +PA++ W+E S
Sbjct: 717 IFMSNSYPRDFVNCSTLPALNLASWREAS 745
Score = 36.7 bits (81), Expect = 0.16
Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 9/98 (9%)
Query: 55 DETEWRRTDGSCNNLYYPTRGAYHTPTFRILPADFREDFE------PRLTSSGKEYPLAR 108
++ ++R G CNN PT GA + R LPA++ + F P + +G LAR
Sbjct: 169 EQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALAR 228
Query: 109 HIKNNLLTIGLATDAKLTQLSAYYIEFMAIDVVSAHDI 146
+ N + + TD +LT + FM + HD+
Sbjct: 229 AVSNEI--VRFPTD-QLTPDQERSLMFMQWGQLLDHDL 263
>M17176-1|AAA60346.1| 745|Homo sapiens MPO protein.
Length = 745
Score = 64.9 bits (151), Expect = 5e-10
Identities = 58/269 (21%), Positives = 114/269 (42%), Gaps = 12/269 (4%)
Query: 168 YDETVVPQIALEYAYASRWFHTIQYGAQKLFDKNFNLIKEVPMVNFS---LSVQSLAIGD 224
Y+++V P+IA + A R+ HT+ D + ++ P V S + + +
Sbjct: 482 YNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEG 541
Query: 225 IMSTVTRGSYYQAT--GKADSTVDPDISDIGLGPVQEV-FDIPTTDLAKGRYFGLPSYTK 281
+ + RG + + +I + V + D+P ++ + R GLP Y
Sbjct: 542 GIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNA 601
Query: 282 YRDFCSGYSKKHVDFDDLTDHISDEKI-QQLKQVYETAEDIELMAGIWVENVIEGAQVPP 340
+R FC + V L + + K+ ++L + Y T +I++ G E + +V P
Sbjct: 602 WRRFCGLPQPETVG--QLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGP 659
Query: 341 TVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQPK 400
+ C++ Q ++ DR W+E F+ +Q Q + + SL ++C +
Sbjct: 660 LLACIIGTQFRKLRDGDRFWWENEG---VFSMQQRQALAQISLPRIICDNTGITTVSKNN 716
Query: 401 AFTIVGKGNNLVSCDEIPAIDFTHWKEES 429
F + V+C +PA++ W+E S
Sbjct: 717 IFMSNSYPRDFVNCSTLPALNLASWREAS 745
Score = 36.7 bits (81), Expect = 0.16
Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 9/98 (9%)
Query: 55 DETEWRRTDGSCNNLYYPTRGAYHTPTFRILPADFREDFE------PRLTSSGKEYPLAR 108
++ ++R G CNN PT GA + R LPA++ + F P + +G LAR
Sbjct: 169 EQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALAR 228
Query: 109 HIKNNLLTIGLATDAKLTQLSAYYIEFMAIDVVSAHDI 146
+ N + + TD +LT + FM + HD+
Sbjct: 229 AVSNEI--VRFPTD-QLTPDQERSLMFMQWGQLLDHDL 263
>J02694-1|AAA59896.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 64.9 bits (151), Expect = 5e-10
Identities = 58/269 (21%), Positives = 114/269 (42%), Gaps = 12/269 (4%)
Query: 168 YDETVVPQIALEYAYASRWFHTIQYGAQKLFDKNFNLIKEVPMVNFS---LSVQSLAIGD 224
Y+++V P+IA + A R+ HT+ D + ++ P V S + + +
Sbjct: 482 YNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEG 541
Query: 225 IMSTVTRGSYYQAT--GKADSTVDPDISDIGLGPVQEV-FDIPTTDLAKGRYFGLPSYTK 281
+ + RG + + +I + V + D+P ++ + R GLP Y
Sbjct: 542 GIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNA 601
Query: 282 YRDFCSGYSKKHVDFDDLTDHISDEKI-QQLKQVYETAEDIELMAGIWVENVIEGAQVPP 340
+R FC + V L + + K+ ++L + Y T +I++ G E + +V P
Sbjct: 602 WRRFCGLPQPETVG--QLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGP 659
Query: 341 TVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQPK 400
+ C++ Q ++ DR W+E F+ +Q Q + + SL ++C +
Sbjct: 660 LLACIIGTQFRKLRDGDRFWWENEG---VFSMQQRQALAQISLPRIICDNTGITTVSKNN 716
Query: 401 AFTIVGKGNNLVSCDEIPAIDFTHWKEES 429
F + V+C +PA++ W+E S
Sbjct: 717 IFMSNSYPRDFVNCSTLPALNLASWREAS 745
Score = 36.7 bits (81), Expect = 0.16
Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 9/98 (9%)
Query: 55 DETEWRRTDGSCNNLYYPTRGAYHTPTFRILPADFREDFE------PRLTSSGKEYPLAR 108
++ ++R G CNN PT GA + R LPA++ + F P + +G LAR
Sbjct: 169 EQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALAR 228
Query: 109 HIKNNLLTIGLATDAKLTQLSAYYIEFMAIDVVSAHDI 146
+ N + + TD +LT + FM + HD+
Sbjct: 229 AVSNEI--VRFPTD-QLTPDQERSLMFMQWGQLLDHDL 263
>DQ088846-1|AAY68218.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 64.9 bits (151), Expect = 5e-10
Identities = 58/269 (21%), Positives = 114/269 (42%), Gaps = 12/269 (4%)
Query: 168 YDETVVPQIALEYAYASRWFHTIQYGAQKLFDKNFNLIKEVPMVNFS---LSVQSLAIGD 224
Y+++V P+IA + A R+ HT+ D + ++ P V S + + +
Sbjct: 482 YNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEG 541
Query: 225 IMSTVTRGSYYQAT--GKADSTVDPDISDIGLGPVQEV-FDIPTTDLAKGRYFGLPSYTK 281
+ + RG + + +I + V + D+P ++ + R GLP Y
Sbjct: 542 GIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNA 601
Query: 282 YRDFCSGYSKKHVDFDDLTDHISDEKI-QQLKQVYETAEDIELMAGIWVENVIEGAQVPP 340
+R FC + V L + + K+ ++L + Y T +I++ G E + +V P
Sbjct: 602 WRRFCGLPQPETVG--QLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGP 659
Query: 341 TVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQPK 400
+ C++ Q ++ DR W+E F+ +Q Q + + SL ++C +
Sbjct: 660 LLACIIGTQFRKLRDGDRFWWENEG---VFSMQQRQALAQISLPRIICDNTGITTVSKNN 716
Query: 401 AFTIVGKGNNLVSCDEIPAIDFTHWKEES 429
F + V+C +PA++ W+E S
Sbjct: 717 IFMSNSYPRDFVNCSTLPALNLASWREAS 745
Score = 36.7 bits (81), Expect = 0.16
Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 9/98 (9%)
Query: 55 DETEWRRTDGSCNNLYYPTRGAYHTPTFRILPADFREDFE------PRLTSSGKEYPLAR 108
++ ++R G CNN PT GA + R LPA++ + F P + +G LAR
Sbjct: 169 EQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALAR 228
Query: 109 HIKNNLLTIGLATDAKLTQLSAYYIEFMAIDVVSAHDI 146
+ N + + TD +LT + FM + HD+
Sbjct: 229 AVSNEI--VRFPTD-QLTPDQERSLMFMQWGQLLDHDL 263
>BC130476-1|AAI30477.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 64.9 bits (151), Expect = 5e-10
Identities = 58/269 (21%), Positives = 114/269 (42%), Gaps = 12/269 (4%)
Query: 168 YDETVVPQIALEYAYASRWFHTIQYGAQKLFDKNFNLIKEVPMVNFS---LSVQSLAIGD 224
Y+++V P+IA + A R+ HT+ D + ++ P V S + + +
Sbjct: 482 YNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEG 541
Query: 225 IMSTVTRGSYYQAT--GKADSTVDPDISDIGLGPVQEV-FDIPTTDLAKGRYFGLPSYTK 281
+ + RG + + +I + V + D+P ++ + R GLP Y
Sbjct: 542 GIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNA 601
Query: 282 YRDFCSGYSKKHVDFDDLTDHISDEKI-QQLKQVYETAEDIELMAGIWVENVIEGAQVPP 340
+R FC + V L + + K+ ++L + Y T +I++ G E + +V P
Sbjct: 602 WRRFCGLPQPETVG--QLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGP 659
Query: 341 TVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQPK 400
+ C++ Q ++ DR W+E F+ +Q Q + + SL ++C +
Sbjct: 660 LLACIIGTQFRKLRDGDRFWWENEG---VFSMQQRQALAQISLPRIICDNTGITTVSKNN 716
Query: 401 AFTIVGKGNNLVSCDEIPAIDFTHWKEES 429
F + V+C +PA++ W+E S
Sbjct: 717 IFMSNSYPRDFVNCSTLPALNLASWREAS 745
Score = 36.7 bits (81), Expect = 0.16
Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 9/98 (9%)
Query: 55 DETEWRRTDGSCNNLYYPTRGAYHTPTFRILPADFREDFE------PRLTSSGKEYPLAR 108
++ ++R G CNN PT GA + R LPA++ + F P + +G LAR
Sbjct: 169 EQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALAR 228
Query: 109 HIKNNLLTIGLATDAKLTQLSAYYIEFMAIDVVSAHDI 146
+ N + + TD +LT + FM + HD+
Sbjct: 229 AVSNEI--VRFPTD-QLTPDQERSLMFMQWGQLLDHDL 263
>J02970-1|AAA61216.1| 876|Homo sapiens TPO protein.
Length = 876
Score = 62.9 bits (146), Expect = 2e-09
Identities = 39/149 (26%), Positives = 69/149 (46%), Gaps = 5/149 (3%)
Query: 279 YTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQLKQVYETAEDIELMAGIWVENVIEGAQV 338
Y ++R+FC G + D T S ++ +Y+ ++I++ G EN + A+
Sbjct: 534 YNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRART 592
Query: 339 PPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQ 398
P CL+ Q+K D W+E H F Q +E+ K SL+ ++C + ++
Sbjct: 593 GPLFACLIGKQMKALRDGDWFWWE---NSHVFTDAQRRELEKHSLSRVIC-DNTGLTRVP 648
Query: 399 PKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
AF + + SCD IP ++ W+E
Sbjct: 649 MDAFQVGKFPEDFESCDSIPGMNLEAWRE 677
>AF533531-1|AAN04474.1| 347|Homo sapiens thyroid peroxidase isoform
2/4 protein.
Length = 347
Score = 62.9 bits (146), Expect = 2e-09
Identities = 39/149 (26%), Positives = 69/149 (46%), Gaps = 5/149 (3%)
Query: 279 YTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQLKQVYETAEDIELMAGIWVENVIEGAQV 338
Y ++R+FC G + D T S ++ +Y+ ++I++ G EN + A+
Sbjct: 65 YNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRART 123
Query: 339 PPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQ 398
P CL+ Q+K D W+E H F Q +E+ K SL+ ++C + ++
Sbjct: 124 GPLFACLIGKQMKALRDGDWFWWE---NSHVFTDAQRRELEKHSLSRVIC-DNTGLTRVP 179
Query: 399 PKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
AF + + SCD IP ++ W+E
Sbjct: 180 MDAFQVGKFPEDFESCDSIPGMNLEAWRE 208
>AF533530-1|AAN04473.1| 350|Homo sapiens thyroid peroxidase isoform
2/3 protein.
Length = 350
Score = 62.9 bits (146), Expect = 2e-09
Identities = 39/149 (26%), Positives = 69/149 (46%), Gaps = 5/149 (3%)
Query: 279 YTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQLKQVYETAEDIELMAGIWVENVIEGAQV 338
Y ++R+FC G + D T S ++ +Y+ ++I++ G EN + A+
Sbjct: 65 YNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRART 123
Query: 339 PPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQ 398
P CL+ Q+K D W+E H F Q +E+ K SL+ ++C + ++
Sbjct: 124 GPLFACLIGKQMKALRDGDWFWWE---NSHVFTDAQRRELEKHSLSRVIC-DNTGLTRVP 179
Query: 399 PKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
AF + + SCD IP ++ W+E
Sbjct: 180 MDAFQVGKFPEDFESCDSIPGMNLEAWRE 208
>X14346-1|CAA32530.1| 702|Homo sapiens eosinophil preperoxidase (AA
-127 to 575) protein.
Length = 702
Score = 60.5 bits (140), Expect = 1e-08
Identities = 54/266 (20%), Positives = 112/266 (42%), Gaps = 14/266 (5%)
Query: 168 YDETVVPQIALEYAYASRWFHTIQYGAQKLFDKNFNLI---KEVPMVNFSLSVQSLAIGD 224
Y V P++A + A R+ HT+ D + VP+ + + +
Sbjct: 442 YCSNVDPRVANVFTLAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLSSAFFASWRIVYEG 501
Query: 225 IMSTVTRGSYYQAT--GKADSTVDPDISDIGLGPVQEV-FDIPTTDLAKGRYFGLPSYTK 281
+ + RG + D+ + ++ D V+ + D+ ++ + R GLP Y
Sbjct: 502 GIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQVRRIGLDLAALNMQRSRDHGLPGYNA 561
Query: 282 YRDFCSGYSKKHVDFDDLTDHISDEKI-QQLKQVYETAEDIELMAGIWVENVIEGAQVPP 340
+R FC G S+ + L+ + ++ + ++ +Y T ++I++ G E ++ GA+V P
Sbjct: 562 WRRFC-GLSQPR-NLAQLSRVLKNQDLARKFLNLYGTPDNIDIWIGAIAEPLLPGARVGP 619
Query: 341 TVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQPK 400
+ CL NQ +R+ R F+ Q + + + SL+ ++C + +
Sbjct: 620 LLACLFENQFRRA----ETETGSGGRTRCFHQRQRKALSRISLSRIIC-DNTGITTVSRD 674
Query: 401 AFTIVGKGNNLVSCDEIPAIDFTHWK 426
F V+C IP ++ + W+
Sbjct: 675 IFRANIYPRGFVNCSRIPRLNLSAWR 700
Score = 31.5 bits (68), Expect = 5.9
Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 12/95 (12%)
Query: 29 LLTDEQRQAYEKANILSTCA--NNIQPCDETEWRRTDGSCNNLYYPTRGAYHTPTFRILP 86
+LT+ Q + +A S CA + + C + ++R G CNN P GA + R LP
Sbjct: 105 VLTEPQLRLLSQA---SGCALRDQAERCSD-KYRTITGRCNNKRRPLLGASNQALARWLP 160
Query: 87 ADFRE------DFEPRLTSSGKEYPLARHIKNNLL 115
A++ + + P +G PL R + N ++
Sbjct: 161 AEYEDGLSLPFGWTPSRRRNGFLLPLVRAVSNQIV 195
>X17358-1|CAA35235.1| 876|Homo sapiens protein ( Human mRNA from
alternatively spliced TPO-2 gene for thyroid peroxidase
(EC.1.11.1.7). ).
Length = 876
Score = 59.7 bits (138), Expect = 2e-08
Identities = 38/149 (25%), Positives = 68/149 (45%), Gaps = 5/149 (3%)
Query: 279 YTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQLKQVYETAEDIELMAGIWVENVIEGAQV 338
Y ++R+FC G + D T S ++ +Y+ ++I++ G EN + A+
Sbjct: 534 YNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRART 592
Query: 339 PPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQ 398
P CL+ Q+K D W+E H F Q +E+ K SL+ ++C + ++
Sbjct: 593 GPLFACLIGKQMKALRDGDWFWWE---NSHVFTDAQRRELEKHSLSRVIC-DNTGLTRVP 648
Query: 399 PKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
AF + + SCD I ++ W+E
Sbjct: 649 MDAFQVGKFPEDFESCDSITGMNLEAWRE 677
>BC114938-1|AAI14939.1| 1551|Homo sapiens dual oxidase 1 protein.
Length = 1551
Score = 52.0 bits (119), Expect = 4e-06
Identities = 53/216 (24%), Positives = 98/216 (45%), Gaps = 14/216 (6%)
Query: 195 QKLFDKNFNLIKEVPMVN--FSLSVQSLAIGDIMSTVTRGSYYQATGKADSTVDPDISDI 252
Q + ++N ++ + + + N +S SL + + + G Q + D + D+ D
Sbjct: 348 QGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDF 407
Query: 253 GLGPVQ-EVFDIPTTDLAKGRYFGLPSYTKYRDFCSGYS--KKHVDFDDLTDHISDEKIQ 309
GP++ D + L +GR GLPSYTK R G S + D + +D ++
Sbjct: 408 WPGPLKFSRTDHLASCLQRGRDLGLPSYTKAR-AALGLSPITRWQDINPALSRSNDTVLE 466
Query: 310 QLKQVY-ETAEDIELMAGIWVENVIEGAQVP-PTVHCLLSNQLKRSIIIDRHWYERPNRP 367
+Y + +EL+ G ++E + P P ++ Q R DR+W+E R
Sbjct: 467 ATAALYNQDLSWLELLPG----GLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFEN-TRN 521
Query: 368 HAFNHEQLQEIRKASLA-LLLCYVGDDVEKIQPKAF 402
F+ ++++EIR +L +L+ + D +QP F
Sbjct: 522 GLFSKKEIEEIRNTTLQDVLVAVINIDPSALQPNVF 557
>BC114628-1|AAI14629.1| 1551|Homo sapiens dual oxidase 1 protein.
Length = 1551
Score = 52.0 bits (119), Expect = 4e-06
Identities = 53/216 (24%), Positives = 98/216 (45%), Gaps = 14/216 (6%)
Query: 195 QKLFDKNFNLIKEVPMVN--FSLSVQSLAIGDIMSTVTRGSYYQATGKADSTVDPDISDI 252
Q + ++N ++ + + + N +S SL + + + G Q + D + D+ D
Sbjct: 348 QGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDF 407
Query: 253 GLGPVQ-EVFDIPTTDLAKGRYFGLPSYTKYRDFCSGYS--KKHVDFDDLTDHISDEKIQ 309
GP++ D + L +GR GLPSYTK R G S + D + +D ++
Sbjct: 408 WPGPLKFSRTDHLASCLQRGRDLGLPSYTKAR-AALGLSPITRWQDINPALSRSNDTVLE 466
Query: 310 QLKQVY-ETAEDIELMAGIWVENVIEGAQVP-PTVHCLLSNQLKRSIIIDRHWYERPNRP 367
+Y + +EL+ G ++E + P P ++ Q R DR+W+E R
Sbjct: 467 ATAALYNQDLSWLELLPG----GLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFEN-TRN 521
Query: 368 HAFNHEQLQEIRKASLA-LLLCYVGDDVEKIQPKAF 402
F+ ++++EIR +L +L+ + D +QP F
Sbjct: 522 GLFSKKEIEEIRNTTLQDVLVAVINIDPSALQPNVF 557
>AF230495-1|AAF73921.1| 1551|Homo sapiens NADPH thyroid oxidase 1
protein.
Length = 1551
Score = 52.0 bits (119), Expect = 4e-06
Identities = 53/216 (24%), Positives = 98/216 (45%), Gaps = 14/216 (6%)
Query: 195 QKLFDKNFNLIKEVPMVN--FSLSVQSLAIGDIMSTVTRGSYYQATGKADSTVDPDISDI 252
Q + ++N ++ + + + N +S SL + + + G Q + D + D+ D
Sbjct: 348 QGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDF 407
Query: 253 GLGPVQ-EVFDIPTTDLAKGRYFGLPSYTKYRDFCSGYS--KKHVDFDDLTDHISDEKIQ 309
GP++ D + L +GR GLPSYTK R G S + D + +D ++
Sbjct: 408 WPGPLKFSRTDHLASCLQRGRDLGLPSYTKAR-AALGLSPITRWQDINPALSRSNDTVLE 466
Query: 310 QLKQVY-ETAEDIELMAGIWVENVIEGAQVP-PTVHCLLSNQLKRSIIIDRHWYERPNRP 367
+Y + +EL+ G ++E + P P ++ Q R DR+W+E R
Sbjct: 467 ATAALYNQDLSWLELLPG----GLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFEN-TRN 521
Query: 368 HAFNHEQLQEIRKASLA-LLLCYVGDDVEKIQPKAF 402
F+ ++++EIR +L +L+ + D +QP F
Sbjct: 522 GLFSKKEIEEIRNTTLQDVLVAVINIDPSALQPNVF 557
>AF213465-1|AAF71295.1| 1551|Homo sapiens dual oxidase protein.
Length = 1551
Score = 52.0 bits (119), Expect = 4e-06
Identities = 53/216 (24%), Positives = 98/216 (45%), Gaps = 14/216 (6%)
Query: 195 QKLFDKNFNLIKEVPMVN--FSLSVQSLAIGDIMSTVTRGSYYQATGKADSTVDPDISDI 252
Q + ++N ++ + + + N +S SL + + + G Q + D + D+ D
Sbjct: 348 QGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDF 407
Query: 253 GLGPVQ-EVFDIPTTDLAKGRYFGLPSYTKYRDFCSGYS--KKHVDFDDLTDHISDEKIQ 309
GP++ D + L +GR GLPSYTK R G S + D + +D ++
Sbjct: 408 WPGPLKFSRTDHLASCLQRGRDLGLPSYTKAR-AALGLSPITRWQDINPALSRSNDTVLE 466
Query: 310 QLKQVY-ETAEDIELMAGIWVENVIEGAQVP-PTVHCLLSNQLKRSIIIDRHWYERPNRP 367
+Y + +EL+ G ++E + P P ++ Q R DR+W+E R
Sbjct: 467 ATAALYNQDLSWLELLPG----GLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFEN-TRN 521
Query: 368 HAFNHEQLQEIRKASLA-LLLCYVGDDVEKIQPKAF 402
F+ ++++EIR +L +L+ + D +QP F
Sbjct: 522 GLFSKKEIEEIRNTTLQDVLVAVINIDPSALQPNVF 557
>AF267981-1|AAF78954.1| 1548|Homo sapiens putative NADPH
oxidase/peroxidase DUOX2 protein.
Length = 1548
Score = 46.8 bits (106), Expect = 1e-04
Identities = 48/201 (23%), Positives = 92/201 (45%), Gaps = 18/201 (8%)
Query: 205 IKEVPMVNFSLSVQSLAIGDIMSTVTRGSYYQATGKADSTVDPDISDIGLGPVQ-EVFDI 263
I+E P +N + V L +G M++ Q + D+ V D+ D GP + D
Sbjct: 375 IRENPNLNSTQEVNELLLG--MAS-------QISELEDNIVVEDLRDYWPGPGKFSRTDY 425
Query: 264 PTTDLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQLKQVY-ETAEDIE 322
+ + +GR GLPSY++ G ++ DL ++ + ++ +Y + +E
Sbjct: 426 VASSIQRGRDMGLPSYSQAL-LAFGLDIPR-NWSDLNPNVDPQVLEATAALYNQDLSQLE 483
Query: 323 LMAGIWVENVIEGAQVPPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKAS 382
L+ G +E+ P ++ +Q R DR+W+E R F+ +++++IR +
Sbjct: 484 LLLGGLLES---HGDPGPLFSAIVLDQFVRLRDGDRYWFEN-TRNGLFSKKEIEDIRNTT 539
Query: 383 LA-LLLCYVGDDVEKIQPKAF 402
L +L+ + D +QP F
Sbjct: 540 LRDVLVAVINIDPSALQPNVF 560
>AF230496-1|AAF73922.1| 1548|Homo sapiens NADPH thyroid oxidase 2
protein.
Length = 1548
Score = 46.8 bits (106), Expect = 1e-04
Identities = 48/201 (23%), Positives = 92/201 (45%), Gaps = 18/201 (8%)
Query: 205 IKEVPMVNFSLSVQSLAIGDIMSTVTRGSYYQATGKADSTVDPDISDIGLGPVQ-EVFDI 263
I+E P +N + V L +G M++ Q + D+ V D+ D GP + D
Sbjct: 375 IRENPNLNSTQEVNELLLG--MAS-------QISELEDNIVVEDLRDYWPGPGKFSRTDY 425
Query: 264 PTTDLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQLKQVY-ETAEDIE 322
+ + +GR GLPSY++ G ++ DL ++ + ++ +Y + +E
Sbjct: 426 VASSIQRGRDMGLPSYSQAL-LAFGLDIPR-NWSDLNPNVDPQVLEATAALYNQDLSQLE 483
Query: 323 LMAGIWVENVIEGAQVPPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKAS 382
L+ G +E+ P ++ +Q R DR+W+E R F+ +++++IR +
Sbjct: 484 LLLGGLLES---HGDPGPLFSAIVLDQFVRLRDGDRYWFEN-TRNGLFSKKEIEDIRNTT 539
Query: 383 LA-LLLCYVGDDVEKIQPKAF 402
L +L+ + D +QP F
Sbjct: 540 LRDVLVAVINIDPSALQPNVF 560
>AF181972-1|AAF20055.1| 1210|Homo sapiens NADH/NADPH thyroid oxidase
p138-tox protein.
Length = 1210
Score = 46.8 bits (106), Expect = 1e-04
Identities = 48/201 (23%), Positives = 92/201 (45%), Gaps = 18/201 (8%)
Query: 205 IKEVPMVNFSLSVQSLAIGDIMSTVTRGSYYQATGKADSTVDPDISDIGLGPVQ-EVFDI 263
I+E P +N + V L +G M++ Q + D+ V D+ D GP + D
Sbjct: 37 IRENPNLNSTQEVNELLLG--MAS-------QISELEDNIVVEDLRDYWPGPGKFSRTDY 87
Query: 264 PTTDLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQLKQVY-ETAEDIE 322
+ + +GR GLPSY++ G ++ DL ++ + ++ +Y + +E
Sbjct: 88 VASSIQRGRDMGLPSYSQAL-LAFGLDIPR-NWSDLNPNVDPQVLEATAALYNQDLSQLE 145
Query: 323 LMAGIWVENVIEGAQVPPTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKAS 382
L+ G +E+ P ++ +Q R DR+W+E R F+ +++++IR +
Sbjct: 146 LLLGGLLES---HGDPGPLFSAIVLDQFVRLRDGDRYWFEN-TRNGLFSKKEIEDIRNTT 201
Query: 383 LA-LLLCYVGDDVEKIQPKAF 402
L +L+ + D +QP F
Sbjct: 202 LRDVLVAVINIDPSALQPNVF 222
>AK128591-1|BAC87516.1| 612|Homo sapiens protein ( Homo sapiens
cDNA FLJ46750 fis, clone TRACH3022758, highly similar
to Homo sapiens dual oxidase 1 (DUOX1). ).
Length = 612
Score = 44.8 bits (101), Expect = 6e-04
Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 11/140 (7%)
Query: 268 LAKGRYFGLPSYTKYRDFCSGYS--KKHVDFDDLTDHISDEKIQQLKQVY-ETAEDIELM 324
L +GR GLPSYTK R G S + D + +D ++ +Y + +EL+
Sbjct: 70 LQRGRDLGLPSYTKAR-AALGLSPITRWQDINPALSRSNDTVLEATAALYNQDLSWLELL 128
Query: 325 AGIWVENVIEGAQVP-PTVHCLLSNQLKRSIIIDRHWYERPNRPHAFNHEQLQEIRKASL 383
G ++E + P P ++ Q R DR+W+E R F+ ++++EIR +L
Sbjct: 129 PG----GLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFEN-TRNGLFSKKEIEEIRNTTL 183
Query: 384 A-LLLCYVGDDVEKIQPKAF 402
+L+ + D +QP F
Sbjct: 184 QDVLVAVINIDPSALQPNVF 203
>BC009496-1|AAH09496.2| 218|Homo sapiens PXDN protein protein.
Length = 218
Score = 44.0 bits (99), Expect = 0.001
Identities = 18/53 (33%), Positives = 31/53 (58%)
Query: 375 LQEIRKASLALLLCYVGDDVEKIQPKAFTIVGKGNNLVSCDEIPAIDFTHWKE 427
L +I++ SLA +LC D++ ++Q F + + SCDEIP +D W++
Sbjct: 2 LTQIKQTSLARILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQD 54
>BX538344-1|CAD98107.1| 95|Homo sapiens hypothetical protein
protein.
Length = 95
Score = 36.3 bits (80), Expect = 0.21
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 7/69 (10%)
Query: 54 CDE-TEWRRTDGSCNNLYYPTRGAYHTPTFRILPADFRE------DFEPRLTSSGKEYPL 106
CD + +R G CNN P GA + R LPA++ + + P T +G PL
Sbjct: 11 CDPCSPYRTITGDCNNRRKPAPGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPL 70
Query: 107 ARHIKNNLL 115
AR + N ++
Sbjct: 71 AREVSNKIV 79
>AF533529-1|AAN04472.1| 140|Homo sapiens thyroid peroxidase isoform
6 protein.
Length = 140
Score = 35.1 bits (77), Expect = 0.48
Identities = 19/73 (26%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
Query: 279 YTKYRDFCSGYSKKHVDFDDLTDHISDEKIQQLKQVYETAEDIELMAGIWVENVIEGAQV 338
Y ++R+FC G + D T S ++ +Y+ ++I++ G EN + A+
Sbjct: 63 YNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRART 121
Query: 339 PPTVHCLLSNQLK 351
P CL+ Q+K
Sbjct: 122 GPLFACLIGKQMK 134
>M55702-2|AAA61218.1| 264|Homo sapiens thyroperoxidase protein.
Length = 264
Score = 33.1 bits (72), Expect = 1.9
Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 4/68 (5%)
Query: 360 WYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQPKAFTIVGKGNNLVSCDEIPA 419
W+E H F Q +E+ K SL+ ++C + ++ AF + + SCD I
Sbjct: 2 WWENS---HVFTDAQRRELEKHSLSRVIC-DNTGLTRVPMDAFQVGKFPEDFESCDSITG 57
Query: 420 IDFTHWKE 427
++ W+E
Sbjct: 58 MNLEAWRE 65
>M55702-1|AAA61219.1| 260|Homo sapiens thyroperoxidase protein.
Length = 260
Score = 33.1 bits (72), Expect = 1.9
Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 4/68 (5%)
Query: 360 WYERPNRPHAFNHEQLQEIRKASLALLLCYVGDDVEKIQPKAFTIVGKGNNLVSCDEIPA 419
W+E H F Q +E+ K SL+ ++C + ++ AF + + SCD I
Sbjct: 2 WWENS---HVFTDAQRRELEKHSLSRVIC-DNTGLTRVPMDAFQVGKFPEDFESCDSITG 57
Query: 420 IDFTHWKE 427
++ W+E
Sbjct: 58 MNLEAWRE 65
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.136 0.412
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 63,530,640
Number of Sequences: 224733
Number of extensions: 2679626
Number of successful extensions: 7168
Number of sequences better than 10.0: 48
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 7016
Number of HSP's gapped (non-prelim): 80
length of query: 429
length of database: 73,234,838
effective HSP length: 92
effective length of query: 337
effective length of database: 52,559,402
effective search space: 17712518474
effective search space used: 17712518474
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 67 (31.1 bits)
- SilkBase 1999-2023 -