Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000238-TA|BGIBMGA000238-PA|IPR002007|Haem peroxidase,
animal, IPR010255|Haem peroxidase
(485 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 98 7e-20
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 98 7e-20
U39573-1|AAC50717.1| 712|Homo sapiens salivary peroxidase protein. 73 3e-12
BC107167-1|AAI07168.1| 712|Homo sapiens lactoperoxidase protein. 73 3e-12
BC107166-1|AAI07167.1| 712|Homo sapiens lactoperoxidase protein. 73 3e-12
AY324876-1|AAP72968.1| 712|Homo sapiens lactoperoxidase protein. 73 3e-12
BC132813-1|AAI32814.1| 515|Homo sapiens peroxidasin homolog (Dr... 70 2e-11
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 70 2e-11
AK131524-1|BAD18663.1| 515|Homo sapiens protein ( Homo sapiens ... 70 2e-11
X15377-1|CAA33438.1| 745|Homo sapiens protein ( Human gene for ... 69 3e-11
X04876-2|CAA28565.1| 745|Homo sapiens prepro-myeloperoxidase pr... 69 3e-11
S56200-1|AAB25582.1| 745|Homo sapiens myeloperoxidase protein. 69 3e-11
M19507-1|AAA59863.1| 745|Homo sapiens myeloperoxidase protein. 69 3e-11
M17176-1|AAA60346.1| 745|Homo sapiens MPO protein. 69 3e-11
J02694-1|AAA59896.1| 745|Homo sapiens myeloperoxidase protein. 69 3e-11
DQ088846-1|AAY68218.1| 745|Homo sapiens myeloperoxidase protein. 69 3e-11
BC130476-1|AAI30477.1| 745|Homo sapiens myeloperoxidase protein. 69 3e-11
AK058200-1|BAB71713.1| 494|Homo sapiens protein ( Homo sapiens ... 69 5e-11
X14346-1|CAA32530.1| 702|Homo sapiens eosinophil preperoxidase ... 68 9e-11
M29913-1|AAA58458.1| 715|Homo sapiens eosinophil peroxidase pro... 68 9e-11
DQ054598-1|AAY43126.1| 715|Homo sapiens eosinophil peroxidase p... 68 9e-11
BC114938-1|AAI14939.1| 1551|Homo sapiens dual oxidase 1 protein. 67 1e-10
BC114628-1|AAI14629.1| 1551|Homo sapiens dual oxidase 1 protein. 67 1e-10
AF230495-1|AAF73921.1| 1551|Homo sapiens NADPH thyroid oxidase 1... 67 1e-10
AF213465-1|AAF71295.1| 1551|Homo sapiens dual oxidase protein. 67 1e-10
AF267981-1|AAF78954.1| 1548|Homo sapiens putative NADPH oxidase/... 67 1e-10
AF230496-1|AAF73922.1| 1548|Homo sapiens NADPH thyroid oxidase 2... 67 1e-10
M58151-1|AAA63213.1| 324|Homo sapiens lactoperoxidase protein. 64 8e-10
M25715-1|AAA97517.1| 933|Homo sapiens TPO protein. 60 2e-08
M17755-1|AAA61217.2| 933|Homo sapiens thyroid peroxidase protein. 60 2e-08
J02969-1|AAA61215.1| 933|Homo sapiens TPO protein. 60 2e-08
DQ011222-1|AAY16985.1| 933|Homo sapiens thyroid peroxidase prot... 60 2e-08
BC095448-1|AAH95448.1| 933|Homo sapiens thyroid peroxidase prot... 60 2e-08
AC105450-1|AAX93261.1| 916|Homo sapiens unknown protein. 60 2e-08
AB208960-1|BAD92197.1| 864|Homo sapiens thyroid peroxidase isof... 60 2e-08
S78220-1|AAB21215.1| 599|Homo sapiens prostaglandin endoperoxid... 60 2e-08
S36271-1|AAB22217.1| 599|Homo sapiens prostaglandin G/H synthas... 60 2e-08
M59979-1|AAA03630.1| 599|Homo sapiens prostaglandin endoperoxid... 60 2e-08
DQ180742-1|ABA60099.1| 630|Homo sapiens cyclooxygenase 1b3 prot... 60 2e-08
DQ180741-1|ABA60098.1| 630|Homo sapiens cyclooxygenase 1b2 prot... 60 2e-08
BC029840-1|AAH29840.1| 599|Homo sapiens prostaglandin-endoperox... 60 2e-08
AY449688-1|AAR08907.1| 599|Homo sapiens prostaglandin-endoperox... 60 2e-08
AL359636-8|CAM45741.1| 599|Homo sapiens prostaglandin-endoperox... 60 2e-08
AL162424-11|CAI14715.1| 599|Homo sapiens prostaglandin-endopero... 60 2e-08
AF440204-1|AAL33601.1| 599|Homo sapiens prostaglandin-endoperox... 60 2e-08
U04636-1|AAA57317.1| 604|Homo sapiens cyclooxygenase-2 protein. 58 5e-08
M90100-1|AAA58433.1| 604|Homo sapiens cyclooxygenase-2 protein. 58 5e-08
M31822-1|AAA36439.1| 599|Homo sapiens prostaglandin-endoperoxid... 58 5e-08
L15326-1|AAA35803.1| 604|Homo sapiens endoperoxide synthase typ... 58 5e-08
D28235-1|BAA05698.1| 604|Homo sapiens prostaglandin endoperoxid... 58 5e-08
BC013734-1|AAH13734.1| 604|Homo sapiens prostaglandin-endoperox... 58 5e-08
AY462100-1|AAR23927.1| 604|Homo sapiens cyclooxygenase 2 protein. 58 5e-08
AY382629-1|AAQ75702.1| 604|Homo sapiens prostaglandin-endoperox... 58 5e-08
AY229989-1|AAO38056.1| 604|Homo sapiens prostaglandin-endoperox... 58 5e-08
AL033533-1|CAB41240.1| 604|Homo sapiens prostaglandin-endoperox... 58 5e-08
Y00406-1|CAA68467.1| 933|Homo sapiens protein ( Human mRNA for ... 58 7e-08
S36219-1|AAB22216.1| 562|Homo sapiens prostaglandin G/H synthas... 58 9e-08
AL359636-7|CAM45740.1| 562|Homo sapiens prostaglandin-endoperox... 58 9e-08
AL162424-12|CAI14714.1| 562|Homo sapiens prostaglandin-endopero... 58 9e-08
AY151286-1|AAN52932.1| 339|Homo sapiens cyclooxygenase 2b protein. 56 3e-07
BC009496-1|AAH09496.2| 218|Homo sapiens PXDN protein protein. 44 0.001
X17358-1|CAA35235.1| 876|Homo sapiens protein ( Human mRNA from... 43 0.003
J02970-1|AAA61216.1| 876|Homo sapiens TPO protein. 43 0.003
BC051850-1|AAH51850.1| 343|Homo sapiens transmembrane protein i... 36 0.42
AF439430-1|AAL74416.1| 760|Homo sapiens thyroid peroxidase prot... 36 0.42
AF327923-1|AAK16442.1| 343|Homo sapiens transmembrane protein i... 36 0.42
AL162424-13|CAI14716.1| 156|Homo sapiens prostaglandin-endopero... 32 5.2
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 97.9 bits (233), Expect = 7e-20
Identities = 117/450 (26%), Positives = 199/450 (44%), Gaps = 39/450 (8%)
Query: 2 PKNFEPRLTSSGKEYPLARHIKNNLL-TVGLATDAKLTQLSAYYIEFMAIDVVSAHDILN 60
P+ P +G P+ R + L+ T + D + T + + +F+ D+ S L+
Sbjct: 795 PRGINPHRLYNGHALPMPRLVSTTLIGTETVTPDEQFTHMLMQWGQFLDHDLDSTVVALS 854
Query: 61 YV-VTRPYCCKEEGKSDPMCAPNFIPEFDPVHRFSGHKC--FNMTKPMTFQNL-GCIENG 116
+ C +DP C IP D R SG +C F + P+ + + N
Sbjct: 855 QARFSDGQHCSNVCSNDPPCFSVMIPPNDSRAR-SGARCMFFVRSSPVCGSGMTSLLMNS 913
Query: 117 TTP-SRIDFSTTFFDLSNIY---EFSAGSLNQVRSYEGGQLKYEVV--NGRQF-PSDASD 169
P +I+ T++ D SN+Y E A S+ + S+ G L+ +V +G+ P
Sbjct: 914 VYPREQINQLTSYIDASNVYGSTEHEARSIRDLASHRG-LLRQGIVQRSGKPLLPFATGP 972
Query: 170 NTTCFIKQAIST-GCTRTVP---NGILG-TNLFTTWFWRFHNYVAQQLANLNPSWDDEQL 224
T C + S C N LG T++ T WF R HN +A +L LNP WD + +
Sbjct: 973 PTECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWF-REHNRIATELLKLNPHWDGDTI 1031
Query: 225 FYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYA 284
+Y R IV A + Y +LP++LG+ M + G YD + I +A
Sbjct: 1032 YYETRKIVGAEIQHITYQHWLPKILGEVGM--------RTLGEYHGYDPGINAGIFNAFA 1083
Query: 285 YAS-RWFHTIQYGAQKLFDKNFNFIKE--VPMVNFTLSVQSLAVGDIMSTVTRGSYYQAT 341
A+ R+ HT+ D+NF I + +P+ S + + + RG +
Sbjct: 1084 TAAFRFGHTLVNPLLYRLDENFQPIAQDHLPLHKAFFSPFRIVNEGGIDPLLRG-LFGVA 1142
Query: 342 GK---GDSSVDPDITDVGLGPVQEI-FDIPTADLAKGRYFGLPSYTKYRDFCSGYSKKHV 397
GK ++ ++T+ + D+ ++ +GR G+P Y YR +C+ S H
Sbjct: 1143 GKMRVPSQLLNTELTERLFSMAHTVALDLAAINIQRGRDHGIPPYHDYRVYCN-LSAAHT 1201
Query: 398 DFDDLTDHISDEKIRQ-LKQVYETAEDIEL 426
F+DL + I + +IR+ LK++Y + +I+L
Sbjct: 1202 -FEDLKNEIKNPEIREKLKRLYGSTLNIDL 1230
Score = 46.0 bits (104), Expect = 3e-04
Identities = 19/54 (35%), Positives = 33/54 (61%)
Query: 430 QLQEIRKASLALLLCYVGDDVEKIQPNPFVIVGKGNNLVSCDEIPAIDFTYWKE 483
QL +I++ SLA +LC D++ ++Q + F + + SCDEIP +D W++
Sbjct: 1278 QLTQIKQTSLARILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQD 1331
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated antigen
MG50 protein.
Length = 1496
Score = 97.9 bits (233), Expect = 7e-20
Identities = 117/450 (26%), Positives = 199/450 (44%), Gaps = 39/450 (8%)
Query: 2 PKNFEPRLTSSGKEYPLARHIKNNLL-TVGLATDAKLTQLSAYYIEFMAIDVVSAHDILN 60
P+ P +G P+ R + L+ T + D + T + + +F+ D+ S L+
Sbjct: 795 PRGINPHRLYNGHALPMPRLVSTTLIGTETVTPDEQFTHMLMQWGQFLDHDLDSTVVALS 854
Query: 61 YV-VTRPYCCKEEGKSDPMCAPNFIPEFDPVHRFSGHKC--FNMTKPMTFQNL-GCIENG 116
+ C +DP C IP D R SG +C F + P+ + + N
Sbjct: 855 QARFSDGQHCSNVCSNDPPCFSVMIPPNDSRAR-SGARCMFFVRSSPVCGSGMTSLLMNS 913
Query: 117 TTP-SRIDFSTTFFDLSNIY---EFSAGSLNQVRSYEGGQLKYEVV--NGRQF-PSDASD 169
P +I+ T++ D SN+Y E A S+ + S+ G L+ +V +G+ P
Sbjct: 914 VYPREQINQLTSYIDASNVYGSTEHEARSIRDLASHRG-LLRQGIVQRSGKPLLPFATGP 972
Query: 170 NTTCFIKQAIST-GCTRTVP---NGILG-TNLFTTWFWRFHNYVAQQLANLNPSWDDEQL 224
T C + S C N LG T++ T WF R HN +A +L LNP WD + +
Sbjct: 973 PTECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWF-REHNRIATELLKLNPHWDGDTI 1031
Query: 225 FYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYA 284
+Y R IV A + Y +LP++LG+ M + G YD + I +A
Sbjct: 1032 YYETRKIVGAEIQHITYQHWLPKILGEVGM--------RTLGEYHGYDPGINAGIFNAFA 1083
Query: 285 YAS-RWFHTIQYGAQKLFDKNFNFIKE--VPMVNFTLSVQSLAVGDIMSTVTRGSYYQAT 341
A+ R+ HT+ D+NF I + +P+ S + + + RG +
Sbjct: 1084 TAAFRFGHTLVNPLLYRLDENFQPIAQDHLPLHKAFFSPFRIVNEGGIDPLLRG-LFGVA 1142
Query: 342 GK---GDSSVDPDITDVGLGPVQEI-FDIPTADLAKGRYFGLPSYTKYRDFCSGYSKKHV 397
GK ++ ++T+ + D+ ++ +GR G+P Y YR +C+ S H
Sbjct: 1143 GKMRVPSQLLNTELTERLFSMAHTVALDLAAINIQRGRDHGIPPYHDYRVYCN-LSAAHT 1201
Query: 398 DFDDLTDHISDEKIRQ-LKQVYETAEDIEL 426
F+DL + I + +IR+ LK++Y + +I+L
Sbjct: 1202 -FEDLKNEIKNPEIREKLKRLYGSTLNIDL 1230
Score = 46.0 bits (104), Expect = 3e-04
Identities = 19/54 (35%), Positives = 33/54 (61%)
Query: 430 QLQEIRKASLALLLCYVGDDVEKIQPNPFVIVGKGNNLVSCDEIPAIDFTYWKE 483
QL +I++ SLA +LC D++ ++Q + F + + SCDEIP +D W++
Sbjct: 1278 QLTQIKQTSLARILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQD 1331
>U39573-1|AAC50717.1| 712|Homo sapiens salivary peroxidase protein.
Length = 712
Score = 72.5 bits (170), Expect = 3e-12
Identities = 113/485 (23%), Positives = 200/485 (41%), Gaps = 49/485 (10%)
Query: 1 MPKNFEPRLTSSGKEYPLARHIKNNLLTVGLATDAKLTQLSAYYIEFMAIDVVSAHDI-- 58
+P + P T +G PLAR + N + VG + + + + FM + HD+
Sbjct: 174 LPFGWTPGKTRNGFPLPLAREVSNKI--VGYLNEEGVLDQNRSLL-FMQWGQIVDHDLDF 230
Query: 59 -----LNYVVTRPYCCKEEGKSDPMCAPNFIPEFDPVHRFSGHKCFNMTKPMTFQNLGCI 113
L C E C P P DP G KC + F
Sbjct: 231 APDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQG-KCMPFFRA-GFVCPTPP 288
Query: 114 ENGTTPSRIDFSTTFFDLSNIYEFSAGSLNQVRSYEGG----QLKYEVVN-GRQF-PSDA 167
+I+ T+F D S +Y +++R+ + EV + G + P D+
Sbjct: 289 YKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDS 348
Query: 168 SDNTTC-FIKQAISTGC-----TRTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDD 221
+ C FI C +R + +L T+ T F R HN +A++L LNP WD
Sbjct: 349 KKPSPCEFINTTARVPCFLAGDSRASEHILLATS--HTLFLREHNRLARELKRLNPQWDG 406
Query: 222 EQLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIAL 281
E+L+ AR I+ AF + + ++LP +LG DHM + + G Y E+V P+I+
Sbjct: 407 EKLYQEARKILGAFVQIITFRDYLPILLG-DHM---QKWIPPYQG----YSESVDPRISN 458
Query: 282 EYAYASRWFHTIQYGAQKLFDKNF---NFIKEVPMVNFTLSVQSLAVGDIMSTVTRGSYY 338
+ +A R+ H + D+N+ E+P+ + + + + RG
Sbjct: 459 VFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLA 518
Query: 339 QATG--KGDSSVDPDITDVGLGPVQEI--FDIPTADLAKGRYFGLPSYTKYRDFCSGYSK 394
+ + K + + ++ + P I FD+ + + R G P Y +R FC
Sbjct: 519 KKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCD--LS 576
Query: 395 KHVDFDDLTDHISDEKI-RQLKQVYETAEDIEL----MAEQLQEIRKASLALLLCYVGDD 449
+ ++L + + + ++L +Y T ++I++ +AE L E + LL C +G
Sbjct: 577 QPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVG-PLLACLLGKQ 635
Query: 450 VEKIQ 454
++I+
Sbjct: 636 FQQIR 640
>BC107167-1|AAI07168.1| 712|Homo sapiens lactoperoxidase protein.
Length = 712
Score = 72.5 bits (170), Expect = 3e-12
Identities = 113/485 (23%), Positives = 200/485 (41%), Gaps = 49/485 (10%)
Query: 1 MPKNFEPRLTSSGKEYPLARHIKNNLLTVGLATDAKLTQLSAYYIEFMAIDVVSAHDI-- 58
+P + P T +G PLAR + N + VG + + + + FM + HD+
Sbjct: 174 LPFGWTPGKTRNGFPLPLAREVSNKI--VGYLNEEGVLDQNRSLL-FMQWGQIVDHDLDF 230
Query: 59 -----LNYVVTRPYCCKEEGKSDPMCAPNFIPEFDPVHRFSGHKCFNMTKPMTFQNLGCI 113
L C E C P P DP G KC + F
Sbjct: 231 APDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQG-KCMPFFRA-GFVCPTPP 288
Query: 114 ENGTTPSRIDFSTTFFDLSNIYEFSAGSLNQVRSYEGG----QLKYEVVN-GRQF-PSDA 167
+I+ T+F D S +Y +++R+ + EV + G + P D+
Sbjct: 289 YKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDS 348
Query: 168 SDNTTC-FIKQAISTGC-----TRTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDD 221
+ C FI C +R + +L T+ T F R HN +A++L LNP WD
Sbjct: 349 KKPSPCEFINTTARVPCFLAGDSRASEHILLATS--HTLFLREHNRLARELKRLNPQWDG 406
Query: 222 EQLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIAL 281
E+L+ AR I+ AF + + ++LP +LG DHM + + G Y E+V P+I+
Sbjct: 407 EKLYQEARKILGAFVQIITFRDYLPILLG-DHM---QKWIPPYQG----YSESVDPRISN 458
Query: 282 EYAYASRWFHTIQYGAQKLFDKNF---NFIKEVPMVNFTLSVQSLAVGDIMSTVTRGSYY 338
+ +A R+ H + D+N+ E+P+ + + + + RG
Sbjct: 459 VFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLA 518
Query: 339 QATG--KGDSSVDPDITDVGLGPVQEI--FDIPTADLAKGRYFGLPSYTKYRDFCSGYSK 394
+ + K + + ++ + P I FD+ + + R G P Y +R FC
Sbjct: 519 KKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCD--LS 576
Query: 395 KHVDFDDLTDHISDEKI-RQLKQVYETAEDIEL----MAEQLQEIRKASLALLLCYVGDD 449
+ ++L + + + ++L +Y T ++I++ +AE L E + LL C +G
Sbjct: 577 QPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVG-PLLACLLGKQ 635
Query: 450 VEKIQ 454
++I+
Sbjct: 636 FQQIR 640
>BC107166-1|AAI07167.1| 712|Homo sapiens lactoperoxidase protein.
Length = 712
Score = 72.5 bits (170), Expect = 3e-12
Identities = 113/485 (23%), Positives = 200/485 (41%), Gaps = 49/485 (10%)
Query: 1 MPKNFEPRLTSSGKEYPLARHIKNNLLTVGLATDAKLTQLSAYYIEFMAIDVVSAHDI-- 58
+P + P T +G PLAR + N + VG + + + + FM + HD+
Sbjct: 174 LPFGWTPGKTRNGFPLPLAREVSNKI--VGYLNEEGVLDQNRSLL-FMQWGQIVDHDLDF 230
Query: 59 -----LNYVVTRPYCCKEEGKSDPMCAPNFIPEFDPVHRFSGHKCFNMTKPMTFQNLGCI 113
L C E C P P DP G KC + F
Sbjct: 231 APDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQG-KCMPFFRA-GFVCPTPP 288
Query: 114 ENGTTPSRIDFSTTFFDLSNIYEFSAGSLNQVRSYEGG----QLKYEVVN-GRQF-PSDA 167
+I+ T+F D S +Y +++R+ + EV + G + P D+
Sbjct: 289 YKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDS 348
Query: 168 SDNTTC-FIKQAISTGC-----TRTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDD 221
+ C FI C +R + +L T+ T F R HN +A++L LNP WD
Sbjct: 349 KKPSPCEFINTTARVPCFLAGDSRASEHILLATS--HTLFLREHNRLARELKRLNPQWDG 406
Query: 222 EQLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIAL 281
E+L+ AR I+ AF + + ++LP +LG DHM + + G Y E+V P+I+
Sbjct: 407 EKLYQEARKILGAFVQIITFRDYLPILLG-DHM---QKWIPPYQG----YSESVDPRISN 458
Query: 282 EYAYASRWFHTIQYGAQKLFDKNF---NFIKEVPMVNFTLSVQSLAVGDIMSTVTRGSYY 338
+ +A R+ H + D+N+ E+P+ + + + + RG
Sbjct: 459 VFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLA 518
Query: 339 QATG--KGDSSVDPDITDVGLGPVQEI--FDIPTADLAKGRYFGLPSYTKYRDFCSGYSK 394
+ + K + + ++ + P I FD+ + + R G P Y +R FC
Sbjct: 519 KKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCD--LS 576
Query: 395 KHVDFDDLTDHISDEKI-RQLKQVYETAEDIEL----MAEQLQEIRKASLALLLCYVGDD 449
+ ++L + + + ++L +Y T ++I++ +AE L E + LL C +G
Sbjct: 577 QPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVG-PLLACLLGKQ 635
Query: 450 VEKIQ 454
++I+
Sbjct: 636 FQQIR 640
>AY324876-1|AAP72968.1| 712|Homo sapiens lactoperoxidase protein.
Length = 712
Score = 72.5 bits (170), Expect = 3e-12
Identities = 113/485 (23%), Positives = 200/485 (41%), Gaps = 49/485 (10%)
Query: 1 MPKNFEPRLTSSGKEYPLARHIKNNLLTVGLATDAKLTQLSAYYIEFMAIDVVSAHDI-- 58
+P + P T +G PLAR + N + VG + + + + FM + HD+
Sbjct: 174 LPFGWTPGKTRNGFPLPLAREVSNKI--VGYLNEEGVLDQNRSLL-FMQWGQIVDHDLDF 230
Query: 59 -----LNYVVTRPYCCKEEGKSDPMCAPNFIPEFDPVHRFSGHKCFNMTKPMTFQNLGCI 113
L C E C P P DP G KC + F
Sbjct: 231 APDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQG-KCMPFFRA-GFVCPTPP 288
Query: 114 ENGTTPSRIDFSTTFFDLSNIYEFSAGSLNQVRSYEGG----QLKYEVVN-GRQF-PSDA 167
+I+ T+F D S +Y +++R+ + EV + G + P D+
Sbjct: 289 YKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDS 348
Query: 168 SDNTTC-FIKQAISTGC-----TRTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDD 221
+ C FI C +R + +L T+ T F R HN +A++L LNP WD
Sbjct: 349 KKPSPCEFINTTARVPCFLAGDSRASEHILLATS--HTLFLREHNRLARELKRLNPQWDG 406
Query: 222 EQLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIAL 281
E+L+ AR I+ AF + + ++LP +LG DHM + + G Y E+V P+I+
Sbjct: 407 EKLYQEARKILGAFVQIITFRDYLPILLG-DHM---QKWIPPYQG----YSESVDPRISN 458
Query: 282 EYAYASRWFHTIQYGAQKLFDKNF---NFIKEVPMVNFTLSVQSLAVGDIMSTVTRGSYY 338
+ +A R+ H + D+N+ E+P+ + + + + RG
Sbjct: 459 VFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLA 518
Query: 339 QATG--KGDSSVDPDITDVGLGPVQEI--FDIPTADLAKGRYFGLPSYTKYRDFCSGYSK 394
+ + K + + ++ + P I FD+ + + R G P Y +R FC
Sbjct: 519 KKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCD--LS 576
Query: 395 KHVDFDDLTDHISDEKI-RQLKQVYETAEDIEL----MAEQLQEIRKASLALLLCYVGDD 449
+ ++L + + + ++L +Y T ++I++ +AE L E + LL C +G
Sbjct: 577 QPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVG-PLLACLLGKQ 635
Query: 450 VEKIQ 454
++I+
Sbjct: 636 FQQIR 640
>BC132813-1|AAI32814.1| 515|Homo sapiens peroxidasin homolog
(Drosophila)-like protein.
Length = 515
Score = 70.1 bits (164), Expect = 2e-11
Identities = 98/377 (25%), Positives = 155/377 (41%), Gaps = 31/377 (8%)
Query: 69 CKEEGKSDPMCAPNFIPEFDPVHRFSGHKCFNMTKPMTFQNL--GCIENGTTPSRIDFST 126
C +DP C P DP + F + P +++ +I+ T
Sbjct: 31 CSSVCTNDPPCFPMNTRHADPRGTHAPCMLFARSSPACASGRPSATVDSVYAREQINQQT 90
Query: 127 TFFDLSNIYEFSAGSLNQVR--SYEGGQLKYEVV---NGRQF-PSDASDNTTCFIKQAIS 180
+ D SN+Y S +R S G LK +G+ P T C ++ S
Sbjct: 91 AYIDGSNVYGSSERESQALRDPSVPRGLLKTGFPWPPSGKPLLPFSTGPPTECARQEQES 150
Query: 181 ----TGCTRTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFH 236
G R + L + T WF R HN VA +L+ LNP W+ ++ AR IV A
Sbjct: 151 PCFLAGDHRANEHLALAA-MHTLWF-REHNRVATELSALNPHWEGNTVYQEARKIVGAEL 208
Query: 237 LQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYAS-RWFHTIQY 295
+ Y +LP+VLG ++ G+R Y+ V I +A A+ R+ HT+
Sbjct: 209 QHITYSHWLPKVLGDP---GTRML----RGYRG-YNPNVNAGIINSFATAAFRFGHTLIN 260
Query: 296 GAQKLFDKNFNFIKE--VPMVNFTLSVQSLAVGDIMSTVTRGSY-YQATGKGDS-SVDPD 351
+ I E +P S + + V RG + A + S + P+
Sbjct: 261 PILYRLNATLGEISEGHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPE 320
Query: 352 ITD-VGLGPVQEIFDIPTADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEK 410
+T + D + +GR G+P Y +R FC+ S K +F+DL + I D +
Sbjct: 321 LTQRLFSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVK--NFEDLQNEIKDSE 378
Query: 411 IRQ-LKQVYETAEDIEL 426
IRQ L+++Y + DI+L
Sbjct: 379 IRQKLRKLYGSPGDIDL 395
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/54 (33%), Positives = 35/54 (64%)
Query: 430 QLQEIRKASLALLLCYVGDDVEKIQPNPFVIVGKGNNLVSCDEIPAIDFTYWKE 483
QL ++++ASL+ +LC GD ++++Q + FV + ++C EIP +D W++
Sbjct: 443 QLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQD 496
>AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase protein.
Length = 1463
Score = 70.1 bits (164), Expect = 2e-11
Identities = 98/377 (25%), Positives = 155/377 (41%), Gaps = 31/377 (8%)
Query: 69 CKEEGKSDPMCAPNFIPEFDPVHRFSGHKCFNMTKPMTFQNL--GCIENGTTPSRIDFST 126
C +DP C P DP + F + P +++ +I+ T
Sbjct: 832 CSSVCTNDPPCFPMNTRHADPRGTHAPCMLFARSSPACASGRPSATVDSVYAREQINQQT 891
Query: 127 TFFDLSNIYEFSAGSLNQVR--SYEGGQLKYEVV---NGRQF-PSDASDNTTCFIKQAIS 180
+ D SN+Y S +R S G LK +G+ P T C ++ S
Sbjct: 892 AYIDGSNVYGSSERESQALRDPSVPRGLLKTGFPWPPSGKPLLPFSTGPPTECARQEQES 951
Query: 181 ----TGCTRTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFH 236
G R + L + T WF R HN VA +L+ LNP W+ ++ AR IV A
Sbjct: 952 PCFLAGDHRANEHLALAA-MHTLWF-REHNRVATELSALNPHWEGNTVYQEARKIVGAEL 1009
Query: 237 LQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYAS-RWFHTIQY 295
+ Y +LP+VLG ++ G+R Y+ V I +A A+ R+ HT+
Sbjct: 1010 QHITYSHWLPKVLGDP---GTRML----RGYRG-YNPNVNAGIINSFATAAFRFGHTLIN 1061
Query: 296 GAQKLFDKNFNFIKE--VPMVNFTLSVQSLAVGDIMSTVTRGSY-YQATGKGDS-SVDPD 351
+ I E +P S + + V RG + A + S + P+
Sbjct: 1062 PILYRLNATLGEISEGHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPE 1121
Query: 352 ITD-VGLGPVQEIFDIPTADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEK 410
+T + D + +GR G+P Y +R FC+ S K +F+DL + I D +
Sbjct: 1122 LTQRLFSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVK--NFEDLQNEIKDSE 1179
Query: 411 IRQ-LKQVYETAEDIEL 426
IRQ L+++Y + DI+L
Sbjct: 1180 IRQKLRKLYGSPGDIDL 1196
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/54 (33%), Positives = 35/54 (64%)
Query: 430 QLQEIRKASLALLLCYVGDDVEKIQPNPFVIVGKGNNLVSCDEIPAIDFTYWKE 483
QL ++++ASL+ +LC GD ++++Q + FV + ++C EIP +D W++
Sbjct: 1244 QLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQD 1297
>AK131524-1|BAD18663.1| 515|Homo sapiens protein ( Homo sapiens
cDNA FLJ43518 fis, clone PERIC2009086, moderately
similar to Homo sapiens melanoma-associated antigen MG50
mRNA. ).
Length = 515
Score = 70.1 bits (164), Expect = 2e-11
Identities = 98/377 (25%), Positives = 155/377 (41%), Gaps = 31/377 (8%)
Query: 69 CKEEGKSDPMCAPNFIPEFDPVHRFSGHKCFNMTKPMTFQNL--GCIENGTTPSRIDFST 126
C +DP C P DP + F + P +++ +I+ T
Sbjct: 31 CNSVCTNDPPCFPMNTRHADPRGTHAPCMLFARSSPACASGRPSATVDSVYAREQINQQT 90
Query: 127 TFFDLSNIYEFSAGSLNQVR--SYEGGQLKYEVV---NGRQF-PSDASDNTTCFIKQAIS 180
+ D SN+Y S +R S G LK +G+ P T C ++ S
Sbjct: 91 AYIDGSNVYGSSERESQALRDPSVPRGLLKTGFPWPPSGKPLLPFSTGPPTECARQEQES 150
Query: 181 ----TGCTRTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFH 236
G R + L + T WF R HN VA +L+ LNP W+ ++ AR IV A
Sbjct: 151 PCFLAGDHRANEHLALAA-MHTLWF-REHNRVATELSALNPHWEGNTVYQEARKIVGAEL 208
Query: 237 LQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYAS-RWFHTIQY 295
+ Y +LP+VLG ++ G+R Y+ V I +A A+ R+ HT+
Sbjct: 209 QHITYSHWLPKVLGDP---GTRML----RGYRG-YNPNVNAGIINSFATAAFRFGHTLIN 260
Query: 296 GAQKLFDKNFNFIKE--VPMVNFTLSVQSLAVGDIMSTVTRGSY-YQATGKGDS-SVDPD 351
+ I E +P S + + V RG + A + S + P+
Sbjct: 261 PILYRLNATLGEISEGHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPE 320
Query: 352 ITD-VGLGPVQEIFDIPTADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEK 410
+T + D + +GR G+P Y +R FC+ S K +F+DL + I D +
Sbjct: 321 LTQRLFSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVK--NFEDLQNEIKDSE 378
Query: 411 IRQ-LKQVYETAEDIEL 426
IRQ L+++Y + DI+L
Sbjct: 379 IRQKLRKLYGSPGDIDL 395
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/54 (33%), Positives = 35/54 (64%)
Query: 430 QLQEIRKASLALLLCYVGDDVEKIQPNPFVIVGKGNNLVSCDEIPAIDFTYWKE 483
QL ++++ASL+ +LC GD ++++Q + FV + ++C EIP +D W++
Sbjct: 443 QLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQD 496
>X15377-1|CAA33438.1| 745|Homo sapiens protein ( Human gene for the
light and heavy chains of myeloperoxidase. ).
Length = 745
Score = 69.3 bits (162), Expect = 3e-11
Identities = 124/487 (25%), Positives = 197/487 (40%), Gaps = 55/487 (11%)
Query: 1 MPKNFEPRLTSSGKEYPLARHIKNNLLTVGLATDAKLTQLSAYYIEFMAIDVVSAHDI-- 58
+P + P + +G LAR + N + V TD +LT + FM + HD+
Sbjct: 209 LPYGWTPGVKRNGFPVALARAVSNEI--VRFPTD-QLTPDQERSLMFMQWGQLLDHDLDF 265
Query: 59 -----LNYVVTRPYCCKEEGKSDPMCAPNFIPEFDPVHRFSGHKCFNMTKPMTFQNLGCI 113
C+ P C P IP DP + C P C
Sbjct: 266 TPEPAARASFVTGVNCETSCVQQPPCFPLKIPPNDPRIKNQAD-CI----PFFRSCPACP 320
Query: 114 -ENGTTPSRIDFSTTFFDLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGR-------QFPS 165
N T ++I+ T+F D S +Y +R+ QL VN R P
Sbjct: 321 GSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSN-QLGLLAVNQRFQDNGRALLPF 379
Query: 166 DASDNTTCFIKQAIS------TGCTRTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSW 219
D + C + + G TR+ L T++ T R HN +A +L +LNP W
Sbjct: 380 DNLHDDPCLLTNRSARIPCFLAGDTRSSEMPEL-TSMHTLLL-REHNRLATELKSLNPRW 437
Query: 220 DDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQI 279
D E+L+ AR IV A + Y ++LP VLG M + +R Y+++V P+I
Sbjct: 438 DGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRK------YLPTYRS-YNDSVDPRI 490
Query: 280 ALEYAYASRWFHTIQYGAQKLFDKNFNFIKEVPMVN----FTLSVQSLAVGDIMSTVTRG 335
A + A R+ HT+ D + ++ P V F S + + G I + RG
Sbjct: 491 ANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGI-DPILRG 549
Query: 336 ---SYYQATGKGDSSVDPDITDVGLGPVQEI-FDIPTADLAKGRYFGLPSYTKYRDFCSG 391
+ + + +VD +I + V I D+P ++ + R GLP Y +R FC
Sbjct: 550 LMATPAKLNRQNQIAVD-EIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGL 608
Query: 392 YSKKHVDFDDLTDHISDEKI-RQLKQVYETAEDIELMAEQLQE--IRKASLA-LLLCYVG 447
+ V L + + K+ R+L + Y T +I++ + E RK + LL C +G
Sbjct: 609 PQPETV--GQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIG 666
Query: 448 DDVEKIQ 454
K++
Sbjct: 667 TQFRKLR 673
>X04876-2|CAA28565.1| 745|Homo sapiens prepro-myeloperoxidase
protein.
Length = 745
Score = 69.3 bits (162), Expect = 3e-11
Identities = 124/487 (25%), Positives = 197/487 (40%), Gaps = 55/487 (11%)
Query: 1 MPKNFEPRLTSSGKEYPLARHIKNNLLTVGLATDAKLTQLSAYYIEFMAIDVVSAHDI-- 58
+P + P + +G LAR + N + V TD +LT + FM + HD+
Sbjct: 209 LPYGWTPGVKRNGFPVALARAVSNEI--VRFPTD-QLTPDQERSLMFMQWGQLLDHDLDF 265
Query: 59 -----LNYVVTRPYCCKEEGKSDPMCAPNFIPEFDPVHRFSGHKCFNMTKPMTFQNLGCI 113
C+ P C P IP DP + C P C
Sbjct: 266 TPEPAARASFVTGVNCETSCVQQPPCFPLKIPPNDPRIKNQAD-CI----PFFRSCPACP 320
Query: 114 -ENGTTPSRIDFSTTFFDLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGR-------QFPS 165
N T ++I+ T+F D S +Y +R+ QL VN R P
Sbjct: 321 GSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSN-QLGLLAVNQRFQDNGRALLPF 379
Query: 166 DASDNTTCFIKQAIS------TGCTRTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSW 219
D + C + + G TR+ L T++ T R HN +A +L +LNP W
Sbjct: 380 DNLHDDPCLLTNRSARIPCFLAGDTRSSEMPEL-TSMHTLLL-REHNRLATELKSLNPRW 437
Query: 220 DDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQI 279
D E+L+ AR IV A + Y ++LP VLG M + +R Y+++V P+I
Sbjct: 438 DGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRK------YLPTYRS-YNDSVDPRI 490
Query: 280 ALEYAYASRWFHTIQYGAQKLFDKNFNFIKEVPMVN----FTLSVQSLAVGDIMSTVTRG 335
A + A R+ HT+ D + ++ P V F S + + G I + RG
Sbjct: 491 ANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGI-DPILRG 549
Query: 336 ---SYYQATGKGDSSVDPDITDVGLGPVQEI-FDIPTADLAKGRYFGLPSYTKYRDFCSG 391
+ + + +VD +I + V I D+P ++ + R GLP Y +R FC
Sbjct: 550 LMATPAKLNRQNQIAVD-EIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGL 608
Query: 392 YSKKHVDFDDLTDHISDEKI-RQLKQVYETAEDIELMAEQLQE--IRKASLA-LLLCYVG 447
+ V L + + K+ R+L + Y T +I++ + E RK + LL C +G
Sbjct: 609 PQPETV--GQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIG 666
Query: 448 DDVEKIQ 454
K++
Sbjct: 667 TQFRKLR 673
>S56200-1|AAB25582.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 69.3 bits (162), Expect = 3e-11
Identities = 124/487 (25%), Positives = 197/487 (40%), Gaps = 55/487 (11%)
Query: 1 MPKNFEPRLTSSGKEYPLARHIKNNLLTVGLATDAKLTQLSAYYIEFMAIDVVSAHDI-- 58
+P + P + +G LAR + N + V TD +LT + FM + HD+
Sbjct: 209 LPYGWTPGVKRNGFPVALARAVSNEI--VRFPTD-QLTPDQERSLMFMQWGQLLDHDLDF 265
Query: 59 -----LNYVVTRPYCCKEEGKSDPMCAPNFIPEFDPVHRFSGHKCFNMTKPMTFQNLGCI 113
C+ P C P IP DP + C P C
Sbjct: 266 TPEPAARASFVTGVNCETSCVQQPPCFPLKIPPNDPRIKNQAD-CI----PFFRSCPACP 320
Query: 114 -ENGTTPSRIDFSTTFFDLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGR-------QFPS 165
N T ++I+ T+F D S +Y +R+ QL VN R P
Sbjct: 321 GSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSN-QLGLLAVNQRFQDNGRALLPF 379
Query: 166 DASDNTTCFIKQAIS------TGCTRTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSW 219
D + C + + G TR+ L T++ T R HN +A +L +LNP W
Sbjct: 380 DNLHDDPCLLTNRSARIPCFLAGDTRSSEMPEL-TSMHTLLL-REHNRLATELKSLNPRW 437
Query: 220 DDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQI 279
D E+L+ AR IV A + Y ++LP VLG M + +R Y+++V P+I
Sbjct: 438 DGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRK------YLPTYRS-YNDSVDPRI 490
Query: 280 ALEYAYASRWFHTIQYGAQKLFDKNFNFIKEVPMVN----FTLSVQSLAVGDIMSTVTRG 335
A + A R+ HT+ D + ++ P V F S + + G I + RG
Sbjct: 491 ANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGI-DPILRG 549
Query: 336 ---SYYQATGKGDSSVDPDITDVGLGPVQEI-FDIPTADLAKGRYFGLPSYTKYRDFCSG 391
+ + + +VD +I + V I D+P ++ + R GLP Y +R FC
Sbjct: 550 LMATPAKLNRQNQIAVD-EIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGL 608
Query: 392 YSKKHVDFDDLTDHISDEKI-RQLKQVYETAEDIELMAEQLQE--IRKASLA-LLLCYVG 447
+ V L + + K+ R+L + Y T +I++ + E RK + LL C +G
Sbjct: 609 PQPETV--GQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIG 666
Query: 448 DDVEKIQ 454
K++
Sbjct: 667 TQFRKLR 673
>M19507-1|AAA59863.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 69.3 bits (162), Expect = 3e-11
Identities = 124/487 (25%), Positives = 197/487 (40%), Gaps = 55/487 (11%)
Query: 1 MPKNFEPRLTSSGKEYPLARHIKNNLLTVGLATDAKLTQLSAYYIEFMAIDVVSAHDI-- 58
+P + P + +G LAR + N + V TD +LT + FM + HD+
Sbjct: 209 LPYGWTPGVKRNGFPVALARAVSNEI--VRFPTD-QLTPDQERSLMFMQWGQLLDHDLDF 265
Query: 59 -----LNYVVTRPYCCKEEGKSDPMCAPNFIPEFDPVHRFSGHKCFNMTKPMTFQNLGCI 113
C+ P C P IP DP + C P C
Sbjct: 266 TPEPAARASFVTGVNCETSCVQQPPCFPLKIPPNDPRIKNQAD-CI----PFFRSCPACP 320
Query: 114 -ENGTTPSRIDFSTTFFDLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGR-------QFPS 165
N T ++I+ T+F D S +Y +R+ QL VN R P
Sbjct: 321 GSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSN-QLGLLAVNQRFQDNGRALLPF 379
Query: 166 DASDNTTCFIKQAIS------TGCTRTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSW 219
D + C + + G TR+ L T++ T R HN +A +L +LNP W
Sbjct: 380 DNLHDDPCLLTNRSARIPCFLAGDTRSSEMPEL-TSMHTLLL-REHNRLATELKSLNPRW 437
Query: 220 DDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQI 279
D E+L+ AR IV A + Y ++LP VLG M + +R Y+++V P+I
Sbjct: 438 DGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRK------YLPTYRS-YNDSVDPRI 490
Query: 280 ALEYAYASRWFHTIQYGAQKLFDKNFNFIKEVPMVN----FTLSVQSLAVGDIMSTVTRG 335
A + A R+ HT+ D + ++ P V F S + + G I + RG
Sbjct: 491 ANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGI-DPILRG 549
Query: 336 ---SYYQATGKGDSSVDPDITDVGLGPVQEI-FDIPTADLAKGRYFGLPSYTKYRDFCSG 391
+ + + +VD +I + V I D+P ++ + R GLP Y +R FC
Sbjct: 550 LMATPAKLNRQNQIAVD-EIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGL 608
Query: 392 YSKKHVDFDDLTDHISDEKI-RQLKQVYETAEDIELMAEQLQE--IRKASLA-LLLCYVG 447
+ V L + + K+ R+L + Y T +I++ + E RK + LL C +G
Sbjct: 609 PQPETV--GQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIG 666
Query: 448 DDVEKIQ 454
K++
Sbjct: 667 TQFRKLR 673
>M17176-1|AAA60346.1| 745|Homo sapiens MPO protein.
Length = 745
Score = 69.3 bits (162), Expect = 3e-11
Identities = 124/487 (25%), Positives = 197/487 (40%), Gaps = 55/487 (11%)
Query: 1 MPKNFEPRLTSSGKEYPLARHIKNNLLTVGLATDAKLTQLSAYYIEFMAIDVVSAHDI-- 58
+P + P + +G LAR + N + V TD +LT + FM + HD+
Sbjct: 209 LPYGWTPGVKRNGFPVALARAVSNEI--VRFPTD-QLTPDQERSLMFMQWGQLLDHDLDF 265
Query: 59 -----LNYVVTRPYCCKEEGKSDPMCAPNFIPEFDPVHRFSGHKCFNMTKPMTFQNLGCI 113
C+ P C P IP DP + C P C
Sbjct: 266 TPEPAARASFVTGVNCETSCVQQPPCFPLKIPPNDPRIKNQAD-CI----PFFRSCPACP 320
Query: 114 -ENGTTPSRIDFSTTFFDLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGR-------QFPS 165
N T ++I+ T+F D S +Y +R+ QL VN R P
Sbjct: 321 GSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSN-QLGLLAVNQRFQDNGRALLPF 379
Query: 166 DASDNTTCFIKQAIS------TGCTRTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSW 219
D + C + + G TR+ L T++ T R HN +A +L +LNP W
Sbjct: 380 DNLHDDPCLLTNRSARIPCFLAGDTRSSEMPEL-TSMHTLLL-REHNRLATELKSLNPRW 437
Query: 220 DDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQI 279
D E+L+ AR IV A + Y ++LP VLG M + +R Y+++V P+I
Sbjct: 438 DGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRK------YLPTYRS-YNDSVDPRI 490
Query: 280 ALEYAYASRWFHTIQYGAQKLFDKNFNFIKEVPMVN----FTLSVQSLAVGDIMSTVTRG 335
A + A R+ HT+ D + ++ P V F S + + G I + RG
Sbjct: 491 ANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGI-DPILRG 549
Query: 336 ---SYYQATGKGDSSVDPDITDVGLGPVQEI-FDIPTADLAKGRYFGLPSYTKYRDFCSG 391
+ + + +VD +I + V I D+P ++ + R GLP Y +R FC
Sbjct: 550 LMATPAKLNRQNQIAVD-EIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGL 608
Query: 392 YSKKHVDFDDLTDHISDEKI-RQLKQVYETAEDIELMAEQLQE--IRKASLA-LLLCYVG 447
+ V L + + K+ R+L + Y T +I++ + E RK + LL C +G
Sbjct: 609 PQPETV--GQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIG 666
Query: 448 DDVEKIQ 454
K++
Sbjct: 667 TQFRKLR 673
>J02694-1|AAA59896.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 69.3 bits (162), Expect = 3e-11
Identities = 124/487 (25%), Positives = 197/487 (40%), Gaps = 55/487 (11%)
Query: 1 MPKNFEPRLTSSGKEYPLARHIKNNLLTVGLATDAKLTQLSAYYIEFMAIDVVSAHDI-- 58
+P + P + +G LAR + N + V TD +LT + FM + HD+
Sbjct: 209 LPYGWTPGVKRNGFPVALARAVSNEI--VRFPTD-QLTPDQERSLMFMQWGQLLDHDLDF 265
Query: 59 -----LNYVVTRPYCCKEEGKSDPMCAPNFIPEFDPVHRFSGHKCFNMTKPMTFQNLGCI 113
C+ P C P IP DP + C P C
Sbjct: 266 TPEPAARASFVTGVNCETSCVQQPPCFPLKIPPNDPRIKNQAD-CI----PFFRSCPACP 320
Query: 114 -ENGTTPSRIDFSTTFFDLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGR-------QFPS 165
N T ++I+ T+F D S +Y +R+ QL VN R P
Sbjct: 321 GSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSN-QLGLLAVNQRFQDNGRALLPF 379
Query: 166 DASDNTTCFIKQAIS------TGCTRTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSW 219
D + C + + G TR+ L T++ T R HN +A +L +LNP W
Sbjct: 380 DNLHDDPCLLTNRSARIPCFLAGDTRSSEMPEL-TSMHTLLL-REHNRLATELKSLNPRW 437
Query: 220 DDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQI 279
D E+L+ AR IV A + Y ++LP VLG M + +R Y+++V P+I
Sbjct: 438 DGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRK------YLPTYRS-YNDSVDPRI 490
Query: 280 ALEYAYASRWFHTIQYGAQKLFDKNFNFIKEVPMVN----FTLSVQSLAVGDIMSTVTRG 335
A + A R+ HT+ D + ++ P V F S + + G I + RG
Sbjct: 491 ANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGI-DPILRG 549
Query: 336 ---SYYQATGKGDSSVDPDITDVGLGPVQEI-FDIPTADLAKGRYFGLPSYTKYRDFCSG 391
+ + + +VD +I + V I D+P ++ + R GLP Y +R FC
Sbjct: 550 LMATPAKLNRQNQIAVD-EIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGL 608
Query: 392 YSKKHVDFDDLTDHISDEKI-RQLKQVYETAEDIELMAEQLQE--IRKASLA-LLLCYVG 447
+ V L + + K+ R+L + Y T +I++ + E RK + LL C +G
Sbjct: 609 PQPETV--GQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIG 666
Query: 448 DDVEKIQ 454
K++
Sbjct: 667 TQFRKLR 673
>DQ088846-1|AAY68218.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 69.3 bits (162), Expect = 3e-11
Identities = 124/487 (25%), Positives = 197/487 (40%), Gaps = 55/487 (11%)
Query: 1 MPKNFEPRLTSSGKEYPLARHIKNNLLTVGLATDAKLTQLSAYYIEFMAIDVVSAHDI-- 58
+P + P + +G LAR + N + V TD +LT + FM + HD+
Sbjct: 209 LPYGWTPGVKRNGFPVALARAVSNEI--VRFPTD-QLTPDQERSLMFMQWGQLLDHDLDF 265
Query: 59 -----LNYVVTRPYCCKEEGKSDPMCAPNFIPEFDPVHRFSGHKCFNMTKPMTFQNLGCI 113
C+ P C P IP DP + C P C
Sbjct: 266 TPEPAARASFVTGVNCETSCVQQPPCFPLKIPPNDPRIKNQAD-CI----PFFRSCPACP 320
Query: 114 -ENGTTPSRIDFSTTFFDLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGR-------QFPS 165
N T ++I+ T+F D S +Y +R+ QL VN R P
Sbjct: 321 GSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSN-QLGLLAVNQRFQDNGRALLPF 379
Query: 166 DASDNTTCFIKQAIS------TGCTRTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSW 219
D + C + + G TR+ L T++ T R HN +A +L +LNP W
Sbjct: 380 DNLHDDPCLLTNRSARIPCFLAGDTRSSEMPEL-TSMHTLLL-REHNRLATELKSLNPRW 437
Query: 220 DDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQI 279
D E+L+ AR IV A + Y ++LP VLG M + +R Y+++V P+I
Sbjct: 438 DGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRK------YLPTYRS-YNDSVDPRI 490
Query: 280 ALEYAYASRWFHTIQYGAQKLFDKNFNFIKEVPMVN----FTLSVQSLAVGDIMSTVTRG 335
A + A R+ HT+ D + ++ P V F S + + G I + RG
Sbjct: 491 ANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGI-DPILRG 549
Query: 336 ---SYYQATGKGDSSVDPDITDVGLGPVQEI-FDIPTADLAKGRYFGLPSYTKYRDFCSG 391
+ + + +VD +I + V I D+P ++ + R GLP Y +R FC
Sbjct: 550 LMATPAKLNRQNQIAVD-EIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGL 608
Query: 392 YSKKHVDFDDLTDHISDEKI-RQLKQVYETAEDIELMAEQLQE--IRKASLA-LLLCYVG 447
+ V L + + K+ R+L + Y T +I++ + E RK + LL C +G
Sbjct: 609 PQPETV--GQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIG 666
Query: 448 DDVEKIQ 454
K++
Sbjct: 667 TQFRKLR 673
>BC130476-1|AAI30477.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 69.3 bits (162), Expect = 3e-11
Identities = 124/487 (25%), Positives = 197/487 (40%), Gaps = 55/487 (11%)
Query: 1 MPKNFEPRLTSSGKEYPLARHIKNNLLTVGLATDAKLTQLSAYYIEFMAIDVVSAHDI-- 58
+P + P + +G LAR + N + V TD +LT + FM + HD+
Sbjct: 209 LPYGWTPGVKRNGFPVALARAVSNEI--VRFPTD-QLTPDQERSLMFMQWGQLLDHDLDF 265
Query: 59 -----LNYVVTRPYCCKEEGKSDPMCAPNFIPEFDPVHRFSGHKCFNMTKPMTFQNLGCI 113
C+ P C P IP DP + C P C
Sbjct: 266 TPEPAARASFVTGVNCETSCVQQPPCFPLKIPPNDPRIKNQAD-CI----PFFRSCPACP 320
Query: 114 -ENGTTPSRIDFSTTFFDLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGR-------QFPS 165
N T ++I+ T+F D S +Y +R+ QL VN R P
Sbjct: 321 GSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSN-QLGLLAVNQRFQDNGRALLPF 379
Query: 166 DASDNTTCFIKQAIS------TGCTRTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSW 219
D + C + + G TR+ L T++ T R HN +A +L +LNP W
Sbjct: 380 DNLHDDPCLLTNRSARIPCFLAGDTRSSEMPEL-TSMHTLLL-REHNRLATELKSLNPRW 437
Query: 220 DDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQI 279
D E+L+ AR IV A + Y ++LP VLG M + +R Y+++V P+I
Sbjct: 438 DGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRK------YLPTYRS-YNDSVDPRI 490
Query: 280 ALEYAYASRWFHTIQYGAQKLFDKNFNFIKEVPMVN----FTLSVQSLAVGDIMSTVTRG 335
A + A R+ HT+ D + ++ P V F S + + G I + RG
Sbjct: 491 ANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGI-DPILRG 549
Query: 336 ---SYYQATGKGDSSVDPDITDVGLGPVQEI-FDIPTADLAKGRYFGLPSYTKYRDFCSG 391
+ + + +VD +I + V I D+P ++ + R GLP Y +R FC
Sbjct: 550 LMATPAKLNRQNQIAVD-EIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGL 608
Query: 392 YSKKHVDFDDLTDHISDEKI-RQLKQVYETAEDIELMAEQLQE--IRKASLA-LLLCYVG 447
+ V L + + K+ R+L + Y T +I++ + E RK + LL C +G
Sbjct: 609 PQPETV--GQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIG 666
Query: 448 DDVEKIQ 454
K++
Sbjct: 667 TQFRKLR 673
>AK058200-1|BAB71713.1| 494|Homo sapiens protein ( Homo sapiens
cDNA FLJ25471 fis, clone TST09553. ).
Length = 494
Score = 68.5 bits (160), Expect = 5e-11
Identities = 69/238 (28%), Positives = 110/238 (46%), Gaps = 18/238 (7%)
Query: 196 LFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMI 255
+ T WF R HN VA +L+ LNP W+ ++ AR IV A + Y +LP+VLG
Sbjct: 1 MHTLWF-REHNRVATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGDP--- 56
Query: 256 EDEIILCNSTGFRDIYDETVVPQIALEYAYAS-RWFHTIQYGAQKLFDKNFNFIKE--VP 312
++ G+R Y+ V I +A A+ R+ HT+ + I E +P
Sbjct: 57 GTRML----RGYRG-YNPNVNAGIINSFATAAFRFGHTLINPILYRLNATLGEISEGHLP 111
Query: 313 MVNFTLSVQSLAVGDIMSTVTRGSY-YQATGKGDS-SVDPDITD-VGLGPVQEIFDIPTA 369
S + + V RG + A + S + P++T + D
Sbjct: 112 FHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSAAVDSAAT 171
Query: 370 DLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQ-LKQVYETAEDIEL 426
+ +GR G+P Y +R FC+ S K +F+DL + I D +IRQ L+++Y + DI+L
Sbjct: 172 IIQRGRDHGIPPYVDFRVFCNLTSVK--NFEDLQNEIKDSEIRQKLRKLYGSPGDIDL 227
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/54 (33%), Positives = 35/54 (64%)
Query: 430 QLQEIRKASLALLLCYVGDDVEKIQPNPFVIVGKGNNLVSCDEIPAIDFTYWKE 483
QL ++++ASL+ +LC GD ++++Q + FV + ++C EIP +D W++
Sbjct: 275 QLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQD 328
>X14346-1|CAA32530.1| 702|Homo sapiens eosinophil preperoxidase (AA
-127 to 575) protein.
Length = 702
Score = 67.7 bits (158), Expect = 9e-11
Identities = 107/458 (23%), Positives = 182/458 (39%), Gaps = 42/458 (9%)
Query: 1 MPKNFEPRLTSSGKEYPLARHIKNNLLTVG---LATDAKLTQLSAYYIEFMAIDV-VSAH 56
+P + P +G PL R + N ++ L +D + + +F+ D+ S
Sbjct: 169 LPFGWTPSRRRNGFLLPLVRAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPE 228
Query: 57 DILNYVVTRPYCCKEEGKSDPMCAPNFIPEFDPVHRFSGHKC--FNMTKPMTFQNLGCIE 114
T C+ P C P IP DP + + C F + P QN +
Sbjct: 229 SPARVAFTAGVDCERTCAQLPPCFPIKIPPNDPRIK-NQRDCIPFFRSAPSCPQNKNRVR 287
Query: 115 NGTTPSRIDFSTTFFDLSNIY--EFSAGSLNQVRSYEGGQLKYEVV---NGRQF-PSDAS 168
N +I+ T+F D S +Y E S + R+ G L NGR P D
Sbjct: 288 N-----QINALTSFVDASMVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNL 342
Query: 169 DNTTCFIKQAIS------TGCTRTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDDE 222
+ C + + G TR+ L T F R HN +A +L LNP W+ +
Sbjct: 343 HDDPCLLTNRSARIPCFLAGDTRSTETPKLAA--MHTLFMREHNRLATELRRLNPRWNGD 400
Query: 223 QLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALE 282
+L+ AR I+ A + Y +FLP VLGK + G Y V P++A
Sbjct: 401 KLYNEARKIMGAMVQIITYRDFLPLVLGKAR-------ARRTLGHYRGYCSNVDPRVANV 453
Query: 283 YAYASRWFHTIQYGAQKLFDKNFNFI---KEVPMVNFTLSVQSLAVGDIMSTVTRG--SY 337
+ A R+ HT+ D + VP+ + + + + + RG +
Sbjct: 454 FTLAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMAT 513
Query: 338 YQATGKGDSSVDPDITDVGLGPVQEI-FDIPTADLAKGRYFGLPSYTKYRDFCSGYSKKH 396
+ D+ + ++ D V+ I D+ ++ + R GLP Y +R FC G S+
Sbjct: 514 PAKLNRQDAMLVDELRDRLFRQVRRIGLDLAALNMQRSRDHGLPGYNAWRRFC-GLSQPR 572
Query: 397 VDFDDLTDHISDEKI-RQLKQVYETAEDIELMAEQLQE 433
+ L+ + ++ + R+ +Y T ++I++ + E
Sbjct: 573 -NLAQLSRVLKNQDLARKFLNLYGTPDNIDIWIGAIAE 609
>M29913-1|AAA58458.1| 715|Homo sapiens eosinophil peroxidase
protein.
Length = 715
Score = 67.7 bits (158), Expect = 9e-11
Identities = 107/458 (23%), Positives = 182/458 (39%), Gaps = 42/458 (9%)
Query: 1 MPKNFEPRLTSSGKEYPLARHIKNNLLTVG---LATDAKLTQLSAYYIEFMAIDV-VSAH 56
+P + P +G PL R + N ++ L +D + + +F+ D+ S
Sbjct: 181 LPFGWTPSRRRNGFLLPLVRAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPE 240
Query: 57 DILNYVVTRPYCCKEEGKSDPMCAPNFIPEFDPVHRFSGHKC--FNMTKPMTFQNLGCIE 114
T C+ P C P IP DP + + C F + P QN +
Sbjct: 241 SPARVAFTAGVDCERTCAQLPPCFPIKIPPNDPRIK-NQRDCIPFFRSAPSCPQNKNRVR 299
Query: 115 NGTTPSRIDFSTTFFDLSNIY--EFSAGSLNQVRSYEGGQLKYEVV---NGRQF-PSDAS 168
N +I+ T+F D S +Y E S + R+ G L NGR P D
Sbjct: 300 N-----QINALTSFVDASMVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNL 354
Query: 169 DNTTCFIKQAIS------TGCTRTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDDE 222
+ C + + G TR+ L T F R HN +A +L LNP W+ +
Sbjct: 355 HDDPCLLTNRSARIPCFLAGDTRSTETPKLAA--MHTLFMREHNRLATELRRLNPRWNGD 412
Query: 223 QLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALE 282
+L+ AR I+ A + Y +FLP VLGK + G Y V P++A
Sbjct: 413 KLYNEARKIMGAMVQIITYRDFLPLVLGKAR-------ARRTLGHYRGYCSNVDPRVANV 465
Query: 283 YAYASRWFHTIQYGAQKLFDKNFNFI---KEVPMVNFTLSVQSLAVGDIMSTVTRG--SY 337
+ A R+ HT+ D + VP+ + + + + + RG +
Sbjct: 466 FTLAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMAT 525
Query: 338 YQATGKGDSSVDPDITDVGLGPVQEI-FDIPTADLAKGRYFGLPSYTKYRDFCSGYSKKH 396
+ D+ + ++ D V+ I D+ ++ + R GLP Y +R FC G S+
Sbjct: 526 PAKLNRQDAMLVDELRDRLFRQVRRIGLDLAALNMQRSRDHGLPGYNAWRRFC-GLSQPR 584
Query: 397 VDFDDLTDHISDEKI-RQLKQVYETAEDIELMAEQLQE 433
+ L+ + ++ + R+ +Y T ++I++ + E
Sbjct: 585 -NLAQLSRVLKNQDLARKFLNLYGTPDNIDIWIGAIAE 621
>DQ054598-1|AAY43126.1| 715|Homo sapiens eosinophil peroxidase
protein.
Length = 715
Score = 67.7 bits (158), Expect = 9e-11
Identities = 107/458 (23%), Positives = 182/458 (39%), Gaps = 42/458 (9%)
Query: 1 MPKNFEPRLTSSGKEYPLARHIKNNLLTVG---LATDAKLTQLSAYYIEFMAIDV-VSAH 56
+P + P +G PL R + N ++ L +D + + +F+ D+ S
Sbjct: 181 LPFGWTPSRRRNGFLLPLVRAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPE 240
Query: 57 DILNYVVTRPYCCKEEGKSDPMCAPNFIPEFDPVHRFSGHKC--FNMTKPMTFQNLGCIE 114
T C+ P C P IP DP + + C F + P QN +
Sbjct: 241 SPARVAFTAGVDCERTCAQLPPCFPIKIPPNDPRIK-NQRDCIPFFRSAPSCPQNKNRVR 299
Query: 115 NGTTPSRIDFSTTFFDLSNIY--EFSAGSLNQVRSYEGGQLKYEVV---NGRQF-PSDAS 168
N +I+ T+F D S +Y E S + R+ G L NGR P D
Sbjct: 300 N-----QINALTSFVDASMVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNL 354
Query: 169 DNTTCFIKQAIS------TGCTRTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDDE 222
+ C + + G TR+ L T F R HN +A +L LNP W+ +
Sbjct: 355 HDDPCLLTNRSARIPCFLAGDTRSTETPKLAA--MHTLFMREHNRLATELRRLNPRWNGD 412
Query: 223 QLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALE 282
+L+ AR I+ A + Y +FLP VLGK + G Y V P++A
Sbjct: 413 KLYNEARKIMGAMVQIITYRDFLPLVLGKAR-------ARRTLGHYRGYCSNVDPRVANV 465
Query: 283 YAYASRWFHTIQYGAQKLFDKNFNFI---KEVPMVNFTLSVQSLAVGDIMSTVTRG--SY 337
+ A R+ HT+ D + VP+ + + + + + RG +
Sbjct: 466 FTLAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMAT 525
Query: 338 YQATGKGDSSVDPDITDVGLGPVQEI-FDIPTADLAKGRYFGLPSYTKYRDFCSGYSKKH 396
+ D+ + ++ D V+ I D+ ++ + R GLP Y +R FC G S+
Sbjct: 526 PAKLNRQDAMLVDELRDRLFRQVRRIGLDLAALNMQRSRDHGLPGYNAWRRFC-GLSQPR 584
Query: 397 VDFDDLTDHISDEKI-RQLKQVYETAEDIELMAEQLQE 433
+ L+ + ++ + R+ +Y T ++I++ + E
Sbjct: 585 -NLAQLSRVLKNQDLARKFLNLYGTPDNIDIWIGAIAE 621
>BC114938-1|AAI14939.1| 1551|Homo sapiens dual oxidase 1 protein.
Length = 1551
Score = 67.3 bits (157), Expect = 1e-10
Identities = 62/201 (30%), Positives = 94/201 (46%), Gaps = 27/201 (13%)
Query: 200 WFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEI 259
WF R+HN AQ+LA +P W+DE+LF AR V+A + + YE+LP L K
Sbjct: 252 WF-RYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFLQKT------- 303
Query: 260 ILCNSTGFRDIYDETVVPQIALEYAYASRWFHT--IQYGA---------QKLFDKNFNFI 308
L TG+R D P I+ E+ AS F + + G Q + ++N +
Sbjct: 304 -LPEYTGYRPFLD----PSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVS 358
Query: 309 KEVPMVNFTLSVQ--SLAVGDIMSTVTRGSYYQATGKGDSSVDPDITDVGLGPVQ-EIFD 365
+ + + N S + SL + + + G Q + D + D+ D GP++ D
Sbjct: 359 RALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTD 418
Query: 366 IPTADLAKGRYFGLPSYTKYR 386
+ L +GR GLPSYTK R
Sbjct: 419 HLASCLQRGRDLGLPSYTKAR 439
>BC114628-1|AAI14629.1| 1551|Homo sapiens dual oxidase 1 protein.
Length = 1551
Score = 67.3 bits (157), Expect = 1e-10
Identities = 62/201 (30%), Positives = 94/201 (46%), Gaps = 27/201 (13%)
Query: 200 WFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEI 259
WF R+HN AQ+LA +P W+DE+LF AR V+A + + YE+LP L K
Sbjct: 252 WF-RYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFLQKT------- 303
Query: 260 ILCNSTGFRDIYDETVVPQIALEYAYASRWFHT--IQYGA---------QKLFDKNFNFI 308
L TG+R D P I+ E+ AS F + + G Q + ++N +
Sbjct: 304 -LPEYTGYRPFLD----PSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVS 358
Query: 309 KEVPMVNFTLSVQ--SLAVGDIMSTVTRGSYYQATGKGDSSVDPDITDVGLGPVQ-EIFD 365
+ + + N S + SL + + + G Q + D + D+ D GP++ D
Sbjct: 359 RALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTD 418
Query: 366 IPTADLAKGRYFGLPSYTKYR 386
+ L +GR GLPSYTK R
Sbjct: 419 HLASCLQRGRDLGLPSYTKAR 439
>AF230495-1|AAF73921.1| 1551|Homo sapiens NADPH thyroid oxidase 1
protein.
Length = 1551
Score = 67.3 bits (157), Expect = 1e-10
Identities = 62/201 (30%), Positives = 94/201 (46%), Gaps = 27/201 (13%)
Query: 200 WFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEI 259
WF R+HN AQ+LA +P W+DE+LF AR V+A + + YE+LP L K
Sbjct: 252 WF-RYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFLQKT------- 303
Query: 260 ILCNSTGFRDIYDETVVPQIALEYAYASRWFHT--IQYGA---------QKLFDKNFNFI 308
L TG+R D P I+ E+ AS F + + G Q + ++N +
Sbjct: 304 -LPEYTGYRPFLD----PSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVS 358
Query: 309 KEVPMVNFTLSVQ--SLAVGDIMSTVTRGSYYQATGKGDSSVDPDITDVGLGPVQ-EIFD 365
+ + + N S + SL + + + G Q + D + D+ D GP++ D
Sbjct: 359 RALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTD 418
Query: 366 IPTADLAKGRYFGLPSYTKYR 386
+ L +GR GLPSYTK R
Sbjct: 419 HLASCLQRGRDLGLPSYTKAR 439
>AF213465-1|AAF71295.1| 1551|Homo sapiens dual oxidase protein.
Length = 1551
Score = 67.3 bits (157), Expect = 1e-10
Identities = 62/201 (30%), Positives = 94/201 (46%), Gaps = 27/201 (13%)
Query: 200 WFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEI 259
WF R+HN AQ+LA +P W+DE+LF AR V+A + + YE+LP L K
Sbjct: 252 WF-RYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFLQKT------- 303
Query: 260 ILCNSTGFRDIYDETVVPQIALEYAYASRWFHT--IQYGA---------QKLFDKNFNFI 308
L TG+R D P I+ E+ AS F + + G Q + ++N +
Sbjct: 304 -LPEYTGYRPFLD----PSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVS 358
Query: 309 KEVPMVNFTLSVQ--SLAVGDIMSTVTRGSYYQATGKGDSSVDPDITDVGLGPVQ-EIFD 365
+ + + N S + SL + + + G Q + D + D+ D GP++ D
Sbjct: 359 RALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTD 418
Query: 366 IPTADLAKGRYFGLPSYTKYR 386
+ L +GR GLPSYTK R
Sbjct: 419 HLASCLQRGRDLGLPSYTKAR 439
>AF267981-1|AAF78954.1| 1548|Homo sapiens putative NADPH
oxidase/peroxidase DUOX2 protein.
Length = 1548
Score = 66.9 bits (156), Expect = 1e-10
Identities = 74/281 (26%), Positives = 122/281 (43%), Gaps = 35/281 (12%)
Query: 126 TTFFDLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCFIKQAISTGCTR 185
T + D S IY S + +RS+ GGQL FP D+ + + +TG +
Sbjct: 176 TGWLDGSAIYGSSHSWSDALRSFSGGQLASGP--DPAFPRDSQNPLLMWAAPDPATG--Q 231
Query: 186 TVPNGILGTN------------LFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVV 233
P G+ L WF R+HN AQ+LA +P W+DE+LF AR V+
Sbjct: 232 NGPRGLYAFGAERGNREPFLQALGLLWF-RYHNLWAQRLARQHPDWEDEELFQHARKRVI 290
Query: 234 AFHLQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQ--IALEYAYASR--- 288
A + + YE+LP L K L TG+R D ++ P+ +A E +++
Sbjct: 291 ATYQNIAVYEWLPSFLQK--------TLPEYTGYRPFLDPSISPEFVVASEQFFSTMVPP 342
Query: 289 --WFHTIQYGAQKLFDKNFNFIKEVPMVN--FTLSVQSLAVGDIMSTVTRGSYYQATGKG 344
+ +K+ +K F + + + N + +L ++ + G Q +
Sbjct: 343 GVYMRNASCHFRKVLNKGFQSSQALRVCNNYWIRENPNLNSTQEVNELLLGMASQISELE 402
Query: 345 DSSVDPDITDVGLGPVQ-EIFDIPTADLAKGRYFGLPSYTK 384
D+ V D+ D GP + D + + +GR GLPSY++
Sbjct: 403 DNIVVEDLRDYWPGPGKFSRTDYVASSIQRGRDMGLPSYSQ 443
>AF230496-1|AAF73922.1| 1548|Homo sapiens NADPH thyroid oxidase 2
protein.
Length = 1548
Score = 66.9 bits (156), Expect = 1e-10
Identities = 74/281 (26%), Positives = 122/281 (43%), Gaps = 35/281 (12%)
Query: 126 TTFFDLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCFIKQAISTGCTR 185
T + D S IY S + +RS+ GGQL FP D+ + + +TG +
Sbjct: 176 TGWLDGSAIYGSSHSWSDALRSFSGGQLASGP--DPAFPRDSQNPLLMWAAPDPATG--Q 231
Query: 186 TVPNGILGTN------------LFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVV 233
P G+ L WF R+HN AQ+LA +P W+DE+LF AR V+
Sbjct: 232 NGPRGLYAFGAERGNREPFLQALGLLWF-RYHNLWAQRLARQHPDWEDEELFQHARKRVI 290
Query: 234 AFHLQMFYYEFLPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQ--IALEYAYASR--- 288
A + + YE+LP L K L TG+R D ++ P+ +A E +++
Sbjct: 291 ATYQNIAVYEWLPSFLQK--------TLPEYTGYRPFLDPSISPEFVVASEQFFSTMVPP 342
Query: 289 --WFHTIQYGAQKLFDKNFNFIKEVPMVN--FTLSVQSLAVGDIMSTVTRGSYYQATGKG 344
+ +K+ +K F + + + N + +L ++ + G Q +
Sbjct: 343 GVYMRNASCHFRKVLNKGFQSSQALRVCNNYWIRENPNLNSTQEVNELLLGMASQISELE 402
Query: 345 DSSVDPDITDVGLGPVQ-EIFDIPTADLAKGRYFGLPSYTK 384
D+ V D+ D GP + D + + +GR GLPSY++
Sbjct: 403 DNIVVEDLRDYWPGPGKFSRTDYVASSIQRGRDMGLPSYSQ 443
>M58151-1|AAA63213.1| 324|Homo sapiens lactoperoxidase protein.
Length = 324
Score = 64.5 bits (150), Expect = 8e-10
Identities = 64/262 (24%), Positives = 122/262 (46%), Gaps = 23/262 (8%)
Query: 205 HNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDHMIEDEIILCNS 264
HN +A++L LNP WD E+L+ AR I+ AF + + ++LP +LG DHM + +
Sbjct: 2 HNRLARELKRLNPQWDGEKLYQEARKILGAFMQIITFRDYLPILLG-DHM---QKWIPPY 57
Query: 265 TGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKNF---NFIKEVPMVNFTLSVQ 321
G Y E+V P+I+ + +A R+ H + D+N+ E+P+ +
Sbjct: 58 QG----YSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTW 113
Query: 322 SLAVGDIMSTVTRGSYYQATG--KGDSSVDPDITDVGLGPVQEI--FDIPTADLAKGRYF 377
+ + + RG + + K + + ++ + P I FD+ + + R
Sbjct: 114 RMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDH 173
Query: 378 GLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKI-RQLKQVYETAEDIEL----MAEQLQ 432
G P Y +R FC + ++L + + + ++L +Y T ++I++ +AE L
Sbjct: 174 GQPGYNSWRAFCD--LSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLV 231
Query: 433 EIRKASLALLLCYVGDDVEKIQ 454
E + LL C +G ++I+
Sbjct: 232 ERGRVG-PLLACLLGKQFQQIR 252
>M25715-1|AAA97517.1| 933|Homo sapiens TPO protein.
Length = 933
Score = 60.1 bits (139), Expect = 2e-08
Identities = 61/271 (22%), Positives = 119/271 (43%), Gaps = 19/271 (7%)
Query: 194 TNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDH 253
T L T W R HN +A L LN W + ++ AR +V A H + +++P +LG +
Sbjct: 404 TALHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEA 462
Query: 254 MIEDEIILCNSTGFRDIYDETVVPQIALEYAYAS-RWFHTIQYGAQKLFDKNFNFIKEVP 312
+ G + YD T P ++ ++ A+ R+ H + + D +F ++P
Sbjct: 463 FQQ-------YVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLP 515
Query: 313 ---MVNFTLSVQSLAVGDIMSTVTRGSYYQAT--GKGDSSVDPDITD-VGLGPVQEIFDI 366
+ S +L G + + RG + D ++ ++T+ + + D+
Sbjct: 516 GLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDL 575
Query: 367 PTADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQLKQVYETAEDIEL 426
+ +L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I++
Sbjct: 576 ASINLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDV 634
Query: 427 MAEQLQE---IRKASLALLLCYVGDDVEKIQ 454
L E R + L C +G ++ ++
Sbjct: 635 WLGGLAENFLPRARTGPLFACLIGKQMKALR 665
>M17755-1|AAA61217.2| 933|Homo sapiens thyroid peroxidase protein.
Length = 933
Score = 60.1 bits (139), Expect = 2e-08
Identities = 61/271 (22%), Positives = 119/271 (43%), Gaps = 19/271 (7%)
Query: 194 TNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDH 253
T L T W R HN +A L LN W + ++ AR +V A H + +++P +LG +
Sbjct: 404 TALHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEA 462
Query: 254 MIEDEIILCNSTGFRDIYDETVVPQIALEYAYAS-RWFHTIQYGAQKLFDKNFNFIKEVP 312
+ G + YD T P ++ ++ A+ R+ H + + D +F ++P
Sbjct: 463 FQQ-------YVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLP 515
Query: 313 ---MVNFTLSVQSLAVGDIMSTVTRGSYYQAT--GKGDSSVDPDITD-VGLGPVQEIFDI 366
+ S +L G + + RG + D ++ ++T+ + + D+
Sbjct: 516 GLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDL 575
Query: 367 PTADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQLKQVYETAEDIEL 426
+ +L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I++
Sbjct: 576 ASINLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDV 634
Query: 427 MAEQLQE---IRKASLALLLCYVGDDVEKIQ 454
L E R + L C +G ++ ++
Sbjct: 635 WLGGLAENFLPRARTGPLFACLIGKQMKALR 665
>J02969-1|AAA61215.1| 933|Homo sapiens TPO protein.
Length = 933
Score = 60.1 bits (139), Expect = 2e-08
Identities = 61/271 (22%), Positives = 119/271 (43%), Gaps = 19/271 (7%)
Query: 194 TNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDH 253
T L T W R HN +A L LN W + ++ AR +V A H + +++P +LG +
Sbjct: 404 TALHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEA 462
Query: 254 MIEDEIILCNSTGFRDIYDETVVPQIALEYAYAS-RWFHTIQYGAQKLFDKNFNFIKEVP 312
+ G + YD T P ++ ++ A+ R+ H + + D +F ++P
Sbjct: 463 FQQ-------YVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLP 515
Query: 313 ---MVNFTLSVQSLAVGDIMSTVTRGSYYQAT--GKGDSSVDPDITD-VGLGPVQEIFDI 366
+ S +L G + + RG + D ++ ++T+ + + D+
Sbjct: 516 GLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDL 575
Query: 367 PTADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQLKQVYETAEDIEL 426
+ +L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I++
Sbjct: 576 ASINLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDV 634
Query: 427 MAEQLQE---IRKASLALLLCYVGDDVEKIQ 454
L E R + L C +G ++ ++
Sbjct: 635 WLGGLAENFLPRARTGPLFACLIGKQMKALR 665
>DQ011222-1|AAY16985.1| 933|Homo sapiens thyroid peroxidase
protein.
Length = 933
Score = 60.1 bits (139), Expect = 2e-08
Identities = 61/271 (22%), Positives = 119/271 (43%), Gaps = 19/271 (7%)
Query: 194 TNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDH 253
T L T W R HN +A L LN W + ++ AR +V A H + +++P +LG +
Sbjct: 404 TALHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEA 462
Query: 254 MIEDEIILCNSTGFRDIYDETVVPQIALEYAYAS-RWFHTIQYGAQKLFDKNFNFIKEVP 312
+ G + YD T P ++ ++ A+ R+ H + + D +F ++P
Sbjct: 463 FQQ-------YVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLP 515
Query: 313 ---MVNFTLSVQSLAVGDIMSTVTRGSYYQAT--GKGDSSVDPDITD-VGLGPVQEIFDI 366
+ S +L G + + RG + D ++ ++T+ + + D+
Sbjct: 516 GLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDL 575
Query: 367 PTADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQLKQVYETAEDIEL 426
+ +L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I++
Sbjct: 576 ASINLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDV 634
Query: 427 MAEQLQE---IRKASLALLLCYVGDDVEKIQ 454
L E R + L C +G ++ ++
Sbjct: 635 WLGGLAENFLPRARTGPLFACLIGKQMKALR 665
>BC095448-1|AAH95448.1| 933|Homo sapiens thyroid peroxidase
protein.
Length = 933
Score = 60.1 bits (139), Expect = 2e-08
Identities = 61/271 (22%), Positives = 119/271 (43%), Gaps = 19/271 (7%)
Query: 194 TNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDH 253
T L T W R HN +A L LN W + ++ AR +V A H + +++P +LG +
Sbjct: 404 TALHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEA 462
Query: 254 MIEDEIILCNSTGFRDIYDETVVPQIALEYAYAS-RWFHTIQYGAQKLFDKNFNFIKEVP 312
+ G + YD T P ++ ++ A+ R+ H + + D +F ++P
Sbjct: 463 FQQ-------YVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLP 515
Query: 313 ---MVNFTLSVQSLAVGDIMSTVTRGSYYQAT--GKGDSSVDPDITD-VGLGPVQEIFDI 366
+ S +L G + + RG + D ++ ++T+ + + D+
Sbjct: 516 GLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDL 575
Query: 367 PTADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQLKQVYETAEDIEL 426
+ +L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I++
Sbjct: 576 ASINLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDV 634
Query: 427 MAEQLQE---IRKASLALLLCYVGDDVEKIQ 454
L E R + L C +G ++ ++
Sbjct: 635 WLGGLAENFLPRARTGPLFACLIGKQMKALR 665
>AC105450-1|AAX93261.1| 916|Homo sapiens unknown protein.
Length = 916
Score = 60.1 bits (139), Expect = 2e-08
Identities = 61/271 (22%), Positives = 119/271 (43%), Gaps = 19/271 (7%)
Query: 194 TNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDH 253
T L T W R HN +A L LN W + ++ AR +V A H + +++P +LG +
Sbjct: 404 TALHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEA 462
Query: 254 MIEDEIILCNSTGFRDIYDETVVPQIALEYAYAS-RWFHTIQYGAQKLFDKNFNFIKEVP 312
+ G + YD T P ++ ++ A+ R+ H + + D +F ++P
Sbjct: 463 FQQ-------YVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLP 515
Query: 313 ---MVNFTLSVQSLAVGDIMSTVTRGSYYQAT--GKGDSSVDPDITD-VGLGPVQEIFDI 366
+ S +L G + + RG + D ++ ++T+ + + D+
Sbjct: 516 GLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDL 575
Query: 367 PTADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQLKQVYETAEDIEL 426
+ +L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I++
Sbjct: 576 ASINLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDV 634
Query: 427 MAEQLQE---IRKASLALLLCYVGDDVEKIQ 454
L E R + L C +G ++ ++
Sbjct: 635 WLGGLAENFLPRARTGPLFACLIGKQMKALR 665
>AB208960-1|BAD92197.1| 864|Homo sapiens thyroid peroxidase isoform
d variant protein.
Length = 864
Score = 60.1 bits (139), Expect = 2e-08
Identities = 61/271 (22%), Positives = 119/271 (43%), Gaps = 19/271 (7%)
Query: 194 TNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDH 253
T L T W R HN +A L LN W + ++ AR +V A H + +++P +LG +
Sbjct: 333 TALHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEA 391
Query: 254 MIEDEIILCNSTGFRDIYDETVVPQIALEYAYAS-RWFHTIQYGAQKLFDKNFNFIKEVP 312
+ G + YD T P ++ ++ A+ R+ H + + D +F ++P
Sbjct: 392 FQQ-------YVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLP 444
Query: 313 ---MVNFTLSVQSLAVGDIMSTVTRGSYYQAT--GKGDSSVDPDITD-VGLGPVQEIFDI 366
+ S +L G + + RG + D ++ ++T+ + + D+
Sbjct: 445 GLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDL 504
Query: 367 PTADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQLKQVYETAEDIEL 426
+ +L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I++
Sbjct: 505 ASINLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDV 563
Query: 427 MAEQLQE---IRKASLALLLCYVGDDVEKIQ 454
L E R + L C +G ++ ++
Sbjct: 564 WLGGLAENFLPRARTGPLFACLIGKQMKALR 594
>S78220-1|AAB21215.1| 599|Homo sapiens prostaglandin endoperoxide
synthase protein.
Length = 599
Score = 59.7 bits (138), Expect = 2e-08
Identities = 63/266 (23%), Positives = 123/266 (46%), Gaps = 22/266 (8%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCF-IKQAISTGCTRTVP 188
DL +IY + Q+R ++ G+LKY+V++G +P + + I V
Sbjct: 228 DLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVG 287
Query: 189 N---GIL-GTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
G+L G L+ T + R HN V L +P+W DEQLF T R I++ +++ E+
Sbjct: 288 QEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEY 347
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ ++ G ++ + L F+ Y +IA+E+ + W H + + K+ +
Sbjct: 348 VQQLSGYFLQLKFDPELLFGVQFQ--YRN----RIAMEFNHLYHW-HPLMPDSFKVGSQE 400
Query: 305 FNFIKEVPMVNFTLSVQSLAVGDIMSTVTRGSYYQATGK--GDSSVDPDITDVGLGPVQE 362
+++ E + N ++ V V ++ +R Q G+ G ++D I V + ++E
Sbjct: 401 YSY--EQFLFNTSMLV-DYGVEALVDAFSR----QIAGRIGGGRNMDHHILHVAVDVIRE 453
Query: 363 IFDIPTADLAKGR-YFGLPSYTKYRD 387
++ + R FG+ YT +++
Sbjct: 454 SREMRLQPFNEYRKRFGMKPYTSFQE 479
>S36271-1|AAB22217.1| 599|Homo sapiens prostaglandin G/H synthase
protein.
Length = 599
Score = 59.7 bits (138), Expect = 2e-08
Identities = 63/266 (23%), Positives = 123/266 (46%), Gaps = 22/266 (8%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCF-IKQAISTGCTRTVP 188
DL +IY + Q+R ++ G+LKY+V++G +P + + I V
Sbjct: 228 DLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVG 287
Query: 189 N---GIL-GTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
G+L G L+ T + R HN V L +P+W DEQLF T R I++ +++ E+
Sbjct: 288 QEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEY 347
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ ++ G ++ + L F+ Y +IA+E+ + W H + + K+ +
Sbjct: 348 VQQLSGYFLQLKFDPELLFGVQFQ--YRN----RIAMEFNHLYHW-HPLMPDSFKVGSQE 400
Query: 305 FNFIKEVPMVNFTLSVQSLAVGDIMSTVTRGSYYQATGK--GDSSVDPDITDVGLGPVQE 362
+++ E + N ++ V V ++ +R Q G+ G ++D I V + ++E
Sbjct: 401 YSY--EQFLFNTSMLV-DYGVEALVDAFSR----QIAGRIGGGRNMDHHILHVAVDVIRE 453
Query: 363 IFDIPTADLAKGR-YFGLPSYTKYRD 387
++ + R FG+ YT +++
Sbjct: 454 SREMRLQPFNEYRKRFGMKPYTSFQE 479
>M59979-1|AAA03630.1| 599|Homo sapiens prostaglandin endoperoxide
synthase protein.
Length = 599
Score = 59.7 bits (138), Expect = 2e-08
Identities = 63/266 (23%), Positives = 123/266 (46%), Gaps = 22/266 (8%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCF-IKQAISTGCTRTVP 188
DL +IY + Q+R ++ G+LKY+V++G +P + + I V
Sbjct: 228 DLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVG 287
Query: 189 N---GIL-GTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
G+L G L+ T + R HN V L +P+W DEQLF T R I++ +++ E+
Sbjct: 288 QEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEY 347
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ ++ G ++ + L F+ Y +IA+E+ + W H + + K+ +
Sbjct: 348 VQQLSGYFLQLKFDPELLFGVQFQ--YRN----RIAMEFNHLYHW-HPLMPDSFKVGSQE 400
Query: 305 FNFIKEVPMVNFTLSVQSLAVGDIMSTVTRGSYYQATGK--GDSSVDPDITDVGLGPVQE 362
+++ E + N ++ V V ++ +R Q G+ G ++D I V + ++E
Sbjct: 401 YSY--EQFLFNTSMLV-DYGVEALVDAFSR----QIAGRIGGGRNMDHHILHVAVDVIRE 453
Query: 363 IFDIPTADLAKGR-YFGLPSYTKYRD 387
++ + R FG+ YT +++
Sbjct: 454 SREMRLQPFNEYRKRFGMKPYTSFQE 479
>DQ180742-1|ABA60099.1| 630|Homo sapiens cyclooxygenase 1b3
protein.
Length = 630
Score = 59.7 bits (138), Expect = 2e-08
Identities = 63/266 (23%), Positives = 123/266 (46%), Gaps = 22/266 (8%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCF-IKQAISTGCTRTVP 188
DL +IY + Q+R ++ G+LKY+V++G +P + + I V
Sbjct: 259 DLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVG 318
Query: 189 N---GIL-GTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
G+L G L+ T + R HN V L +P+W DEQLF T R I++ +++ E+
Sbjct: 319 QEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEY 378
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ ++ G ++ + L F+ Y +IA+E+ + W H + + K+ +
Sbjct: 379 VQQLSGYFLQLKFDPELLFGVQFQ--YRN----RIAMEFNHLYHW-HPLMPDSFKVGSQE 431
Query: 305 FNFIKEVPMVNFTLSVQSLAVGDIMSTVTRGSYYQATGK--GDSSVDPDITDVGLGPVQE 362
+++ E + N ++ V V ++ +R Q G+ G ++D I V + ++E
Sbjct: 432 YSY--EQFLFNTSMLV-DYGVEALVDAFSR----QIAGRIGGGRNMDHHILHVAVDVIRE 484
Query: 363 IFDIPTADLAKGR-YFGLPSYTKYRD 387
++ + R FG+ YT +++
Sbjct: 485 SREMRLQPFNEYRKRFGMKPYTSFQE 510
>DQ180741-1|ABA60098.1| 630|Homo sapiens cyclooxygenase 1b2
protein.
Length = 630
Score = 59.7 bits (138), Expect = 2e-08
Identities = 63/266 (23%), Positives = 123/266 (46%), Gaps = 22/266 (8%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCF-IKQAISTGCTRTVP 188
DL +IY + Q+R ++ G+LKY+V++G +P + + I V
Sbjct: 259 DLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVG 318
Query: 189 N---GIL-GTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
G+L G L+ T + R HN V L +P+W DEQLF T R I++ +++ E+
Sbjct: 319 QEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEY 378
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ ++ G ++ + L F+ Y +IA+E+ + W H + + K+ +
Sbjct: 379 VQQLSGYFLQLKFDPELLFGVQFQ--YRN----RIAMEFNHLYHW-HPLMPDSFKVGSQE 431
Query: 305 FNFIKEVPMVNFTLSVQSLAVGDIMSTVTRGSYYQATGK--GDSSVDPDITDVGLGPVQE 362
+++ E + N ++ V V ++ +R Q G+ G ++D I V + ++E
Sbjct: 432 YSY--EQFLFNTSMLV-DYGVEALVDAFSR----QIAGRIGGGRNMDHHILHVAVDVIRE 484
Query: 363 IFDIPTADLAKGR-YFGLPSYTKYRD 387
++ + R FG+ YT +++
Sbjct: 485 SREMRLQPFNEYRKRFGMKPYTSFQE 510
>BC029840-1|AAH29840.1| 599|Homo sapiens prostaglandin-endoperoxide
synthase 1 (prostaglandin G/H synthase and cyclooxyg
protein.
Length = 599
Score = 59.7 bits (138), Expect = 2e-08
Identities = 63/266 (23%), Positives = 123/266 (46%), Gaps = 22/266 (8%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCF-IKQAISTGCTRTVP 188
DL +IY + Q+R ++ G+LKY+V++G +P + + I V
Sbjct: 228 DLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVG 287
Query: 189 N---GIL-GTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
G+L G L+ T + R HN V L +P+W DEQLF T R I++ +++ E+
Sbjct: 288 QEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEY 347
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ ++ G ++ + L F+ Y +IA+E+ + W H + + K+ +
Sbjct: 348 VQQLSGYFLQLKFDPELLFGVQFQ--YRN----RIAMEFNHLYHW-HPLMPDSFKVGSQE 400
Query: 305 FNFIKEVPMVNFTLSVQSLAVGDIMSTVTRGSYYQATGK--GDSSVDPDITDVGLGPVQE 362
+++ E + N ++ V V ++ +R Q G+ G ++D I V + ++E
Sbjct: 401 YSY--EQFLFNTSMLV-DYGVEALVDAFSR----QIAGRIGGGRNMDHHILHVAVDVIRE 453
Query: 363 IFDIPTADLAKGR-YFGLPSYTKYRD 387
++ + R FG+ YT +++
Sbjct: 454 SREMRLQPFNEYRKRFGMKPYTSFQE 479
>AY449688-1|AAR08907.1| 599|Homo sapiens prostaglandin-endoperoxide
synthase 1 (prostaglandin G/H synthase and cyclooxyg
protein.
Length = 599
Score = 59.7 bits (138), Expect = 2e-08
Identities = 63/266 (23%), Positives = 123/266 (46%), Gaps = 22/266 (8%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCF-IKQAISTGCTRTVP 188
DL +IY + Q+R ++ G+LKY+V++G +P + + I V
Sbjct: 228 DLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVG 287
Query: 189 N---GIL-GTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
G+L G L+ T + R HN V L +P+W DEQLF T R I++ +++ E+
Sbjct: 288 QEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEY 347
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ ++ G ++ + L F+ Y +IA+E+ + W H + + K+ +
Sbjct: 348 VQQLSGYFLQLKFDPELLFGVQFQ--YRN----RIAMEFNHLYHW-HPLMPDSFKVGSQE 400
Query: 305 FNFIKEVPMVNFTLSVQSLAVGDIMSTVTRGSYYQATGK--GDSSVDPDITDVGLGPVQE 362
+++ E + N ++ V V ++ +R Q G+ G ++D I V + ++E
Sbjct: 401 YSY--EQFLFNTSMLV-DYGVEALVDAFSR----QIAGRIGGGRNMDHHILHVAVDVIRE 453
Query: 363 IFDIPTADLAKGR-YFGLPSYTKYRD 387
++ + R FG+ YT +++
Sbjct: 454 SREMRLQPFNEYRKRFGMKPYTSFQE 479
>AL359636-8|CAM45741.1| 599|Homo sapiens prostaglandin-endoperoxide
synthase 1 (prostaglandin G/H synthase and cyclooxyg
protein.
Length = 599
Score = 59.7 bits (138), Expect = 2e-08
Identities = 63/266 (23%), Positives = 123/266 (46%), Gaps = 22/266 (8%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCF-IKQAISTGCTRTVP 188
DL +IY + Q+R ++ G+LKY+V++G +P + + I V
Sbjct: 228 DLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVG 287
Query: 189 N---GIL-GTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
G+L G L+ T + R HN V L +P+W DEQLF T R I++ +++ E+
Sbjct: 288 QEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEY 347
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ ++ G ++ + L F+ Y +IA+E+ + W H + + K+ +
Sbjct: 348 VQQLSGYFLQLKFDPELLFGVQFQ--YRN----RIAMEFNHLYHW-HPLMPDSFKVGSQE 400
Query: 305 FNFIKEVPMVNFTLSVQSLAVGDIMSTVTRGSYYQATGK--GDSSVDPDITDVGLGPVQE 362
+++ E + N ++ V V ++ +R Q G+ G ++D I V + ++E
Sbjct: 401 YSY--EQFLFNTSMLV-DYGVEALVDAFSR----QIAGRIGGGRNMDHHILHVAVDVIRE 453
Query: 363 IFDIPTADLAKGR-YFGLPSYTKYRD 387
++ + R FG+ YT +++
Sbjct: 454 SREMRLQPFNEYRKRFGMKPYTSFQE 479
>AL162424-11|CAI14715.1| 599|Homo sapiens
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H
synthase and cyclooxyg protein.
Length = 599
Score = 59.7 bits (138), Expect = 2e-08
Identities = 63/266 (23%), Positives = 123/266 (46%), Gaps = 22/266 (8%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCF-IKQAISTGCTRTVP 188
DL +IY + Q+R ++ G+LKY+V++G +P + + I V
Sbjct: 228 DLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVG 287
Query: 189 N---GIL-GTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
G+L G L+ T + R HN V L +P+W DEQLF T R I++ +++ E+
Sbjct: 288 QEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEY 347
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ ++ G ++ + L F+ Y +IA+E+ + W H + + K+ +
Sbjct: 348 VQQLSGYFLQLKFDPELLFGVQFQ--YRN----RIAMEFNHLYHW-HPLMPDSFKVGSQE 400
Query: 305 FNFIKEVPMVNFTLSVQSLAVGDIMSTVTRGSYYQATGK--GDSSVDPDITDVGLGPVQE 362
+++ E + N ++ V V ++ +R Q G+ G ++D I V + ++E
Sbjct: 401 YSY--EQFLFNTSMLV-DYGVEALVDAFSR----QIAGRIGGGRNMDHHILHVAVDVIRE 453
Query: 363 IFDIPTADLAKGR-YFGLPSYTKYRD 387
++ + R FG+ YT +++
Sbjct: 454 SREMRLQPFNEYRKRFGMKPYTSFQE 479
>AF440204-1|AAL33601.1| 599|Homo sapiens prostaglandin-endoperoxide
synthase 1 protein.
Length = 599
Score = 59.7 bits (138), Expect = 2e-08
Identities = 63/266 (23%), Positives = 123/266 (46%), Gaps = 22/266 (8%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCF-IKQAISTGCTRTVP 188
DL +IY + Q+R ++ G+LKY+V++G +P + + I V
Sbjct: 228 DLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVG 287
Query: 189 N---GIL-GTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
G+L G L+ T + R HN V L +P+W DEQLF T R I++ +++ E+
Sbjct: 288 QEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEY 347
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ ++ G ++ + L F+ Y +IA+E+ + W H + + K+ +
Sbjct: 348 VQQLSGYFLQLKFDPELLFGVQFQ--YRN----RIAMEFNHLYHW-HPLMPDSFKVGSQE 400
Query: 305 FNFIKEVPMVNFTLSVQSLAVGDIMSTVTRGSYYQATGK--GDSSVDPDITDVGLGPVQE 362
+++ E + N ++ V V ++ +R Q G+ G ++D I V + ++E
Sbjct: 401 YSY--EQFLFNTSMLV-DYGVEALVDAFSR----QIAGRIGGGRNMDHHILHVAVDVIRE 453
Query: 363 IFDIPTADLAKGR-YFGLPSYTKYRD 387
++ + R FG+ YT +++
Sbjct: 454 SREMRLQPFNEYRKRFGMKPYTSFQE 479
>U04636-1|AAA57317.1| 604|Homo sapiens cyclooxygenase-2 protein.
Length = 604
Score = 58.4 bits (135), Expect = 5e-08
Identities = 41/183 (22%), Positives = 86/183 (46%), Gaps = 12/183 (6%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCT 184
DL++IY + ++R ++ G++KY++++G +P D I + +
Sbjct: 215 DLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVG 274
Query: 185 RTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
+ V + G ++ T + R HN V L +P W DEQLF T+R I++ +++ ++
Sbjct: 275 QEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDY 334
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ + G ++ + L + F+ Y +IA E+ W H + ++ D+
Sbjct: 335 VQHLSGYHFKLKFDPELLFNKQFQ--YQN----RIAAEFNTLYHW-HPLLPDTFQIHDQK 387
Query: 305 FNF 307
+N+
Sbjct: 388 YNY 390
>M90100-1|AAA58433.1| 604|Homo sapiens cyclooxygenase-2 protein.
Length = 604
Score = 58.4 bits (135), Expect = 5e-08
Identities = 41/183 (22%), Positives = 86/183 (46%), Gaps = 12/183 (6%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCT 184
DL++IY + ++R ++ G++KY++++G +P D I + +
Sbjct: 215 DLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVG 274
Query: 185 RTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
+ V + G ++ T + R HN V L +P W DEQLF T+R I++ +++ ++
Sbjct: 275 QEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDY 334
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ + G ++ + L + F+ Y +IA E+ W H + ++ D+
Sbjct: 335 VQHLSGYHFKLKFDPELLFNKQFQ--YQN----RIAAEFNTLYHW-HPLLPDTFQIHDQK 387
Query: 305 FNF 307
+N+
Sbjct: 388 YNY 390
>M31822-1|AAA36439.1| 599|Homo sapiens prostaglandin-endoperoxide
synthase-1 protein.
Length = 599
Score = 58.4 bits (135), Expect = 5e-08
Identities = 63/266 (23%), Positives = 122/266 (45%), Gaps = 22/266 (8%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCF-IKQAISTGCTRTVP 188
DL +IY + Q+R ++ G+LKY+V++G +P + + I V
Sbjct: 228 DLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVG 287
Query: 189 N---GIL-GTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
G+L G L+ T + R HN V L +P+W DEQLF T R I++ +++ E+
Sbjct: 288 QEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEY 347
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ ++ G ++ + L F+ Y +IA E+ + W H + + K+ +
Sbjct: 348 VQQLSGYFLQLKFDPELLFGVQFQ--YRN----RIATEFNHLYHW-HPLMPDSFKVGSQE 400
Query: 305 FNFIKEVPMVNFTLSVQSLAVGDIMSTVTRGSYYQATGK--GDSSVDPDITDVGLGPVQE 362
+++ E + N ++ V V ++ +R Q G+ G ++D I V + ++E
Sbjct: 401 YSY--EQFLFNTSMLV-DYGVEALVDAFSR----QIAGRIGGGRNMDHHILHVAVDVIRE 453
Query: 363 IFDIPTADLAKGR-YFGLPSYTKYRD 387
++ + R FG+ YT +++
Sbjct: 454 SREMRLQPFNEYRKRFGMKPYTSFQE 479
>L15326-1|AAA35803.1| 604|Homo sapiens endoperoxide synthase type
II protein.
Length = 604
Score = 58.4 bits (135), Expect = 5e-08
Identities = 41/183 (22%), Positives = 86/183 (46%), Gaps = 12/183 (6%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCT 184
DL++IY + ++R ++ G++KY++++G +P D I + +
Sbjct: 215 DLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVG 274
Query: 185 RTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
+ V + G ++ T + R HN V L +P W DEQLF T+R I++ +++ ++
Sbjct: 275 QEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDY 334
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ + G ++ + L + F+ Y +IA E+ W H + ++ D+
Sbjct: 335 VQHLSGYHFKLKFDPELLFNKQFQ--YQN----RIAAEFNTLYHW-HPLLPDTFQIHDQK 387
Query: 305 FNF 307
+N+
Sbjct: 388 YNY 390
>D28235-1|BAA05698.1| 604|Homo sapiens prostaglandin endoperoxide
synthase-2 protein.
Length = 604
Score = 58.4 bits (135), Expect = 5e-08
Identities = 41/183 (22%), Positives = 86/183 (46%), Gaps = 12/183 (6%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCT 184
DL++IY + ++R ++ G++KY++++G +P D I + +
Sbjct: 215 DLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVG 274
Query: 185 RTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
+ V + G ++ T + R HN V L +P W DEQLF T+R I++ +++ ++
Sbjct: 275 QEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDY 334
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ + G ++ + L + F+ Y +IA E+ W H + ++ D+
Sbjct: 335 VQHLSGYHFKLKFDPELLFNKQFQ--YQN----RIAAEFNTLYHW-HPLLPDTFQIHDQK 387
Query: 305 FNF 307
+N+
Sbjct: 388 YNY 390
>BC013734-1|AAH13734.1| 604|Homo sapiens prostaglandin-endoperoxide
synthase 2 (prostaglandin G/H synthase and cyclooxyg
protein.
Length = 604
Score = 58.4 bits (135), Expect = 5e-08
Identities = 41/183 (22%), Positives = 86/183 (46%), Gaps = 12/183 (6%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCT 184
DL++IY + ++R ++ G++KY++++G +P D I + +
Sbjct: 215 DLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVG 274
Query: 185 RTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
+ V + G ++ T + R HN V L +P W DEQLF T+R I++ +++ ++
Sbjct: 275 QEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDY 334
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ + G ++ + L + F+ Y +IA E+ W H + ++ D+
Sbjct: 335 VQHLSGYHFKLKFDPELLFNKQFQ--YQN----RIAAEFNTLYHW-HPLLPDTFQIHDQK 387
Query: 305 FNF 307
+N+
Sbjct: 388 YNY 390
>AY462100-1|AAR23927.1| 604|Homo sapiens cyclooxygenase 2 protein.
Length = 604
Score = 58.4 bits (135), Expect = 5e-08
Identities = 41/183 (22%), Positives = 86/183 (46%), Gaps = 12/183 (6%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCT 184
DL++IY + ++R ++ G++KY++++G +P D I + +
Sbjct: 215 DLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVG 274
Query: 185 RTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
+ V + G ++ T + R HN V L +P W DEQLF T+R I++ +++ ++
Sbjct: 275 QEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDY 334
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ + G ++ + L + F+ Y +IA E+ W H + ++ D+
Sbjct: 335 VQHLSGYHFKLKFDPELLFNKQFQ--YQN----RIAAEFNTLYHW-HPLLPDTFQIHDQK 387
Query: 305 FNF 307
+N+
Sbjct: 388 YNY 390
>AY382629-1|AAQ75702.1| 604|Homo sapiens prostaglandin-endoperoxide
synthase 2 (prostaglandin G/H synthase and cyclooxyg
protein.
Length = 604
Score = 58.4 bits (135), Expect = 5e-08
Identities = 41/183 (22%), Positives = 86/183 (46%), Gaps = 12/183 (6%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCT 184
DL++IY + ++R ++ G++KY++++G +P D I + +
Sbjct: 215 DLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVG 274
Query: 185 RTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
+ V + G ++ T + R HN V L +P W DEQLF T+R I++ +++ ++
Sbjct: 275 QEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDY 334
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ + G ++ + L + F+ Y +IA E+ W H + ++ D+
Sbjct: 335 VQHLSGYHFKLKFDPELLFNKQFQ--YQN----RIAAEFNTLYHW-HPLLPDTFQIHDQK 387
Query: 305 FNF 307
+N+
Sbjct: 388 YNY 390
>AY229989-1|AAO38056.1| 604|Homo sapiens prostaglandin-endoperoxide
synthase 2 (prostaglandin G/H synthase and cyclooxyg
protein.
Length = 604
Score = 58.4 bits (135), Expect = 5e-08
Identities = 41/183 (22%), Positives = 86/183 (46%), Gaps = 12/183 (6%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCT 184
DL++IY + ++R ++ G++KY++++G +P D I + +
Sbjct: 215 DLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVG 274
Query: 185 RTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
+ V + G ++ T + R HN V L +P W DEQLF T+R I++ +++ ++
Sbjct: 275 QEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDY 334
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ + G ++ + L + F+ Y +IA E+ W H + ++ D+
Sbjct: 335 VQHLSGYHFKLKFDPELLFNKQFQ--YQN----RIAAEFNTLYHW-HPLLPDTFQIHDQK 387
Query: 305 FNF 307
+N+
Sbjct: 388 YNY 390
>AL033533-1|CAB41240.1| 604|Homo sapiens prostaglandin-endoperoxide
synthase 2 (prostaglandin G/H synthase and cyclooxyg
protein.
Length = 604
Score = 58.4 bits (135), Expect = 5e-08
Identities = 41/183 (22%), Positives = 86/183 (46%), Gaps = 12/183 (6%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCT 184
DL++IY + ++R ++ G++KY++++G +P D I + +
Sbjct: 215 DLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVG 274
Query: 185 RTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
+ V + G ++ T + R HN V L +P W DEQLF T+R I++ +++ ++
Sbjct: 275 QEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDY 334
Query: 245 LPEVLGKDHMIEDEIILCNSTGFRDIYDETVVPQIALEYAYASRWFHTIQYGAQKLFDKN 304
+ + G ++ + L + F+ Y +IA E+ W H + ++ D+
Sbjct: 335 VQHLSGYHFKLKFDPELLFNKQFQ--YQN----RIAAEFNTLYHW-HPLLPDTFQIHDQK 387
Query: 305 FNF 307
+N+
Sbjct: 388 YNY 390
>Y00406-1|CAA68467.1| 933|Homo sapiens protein ( Human mRNA for
thyroperoxidase. ).
Length = 933
Score = 58.0 bits (134), Expect = 7e-08
Identities = 60/271 (22%), Positives = 119/271 (43%), Gaps = 19/271 (7%)
Query: 194 TNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDH 253
T L T W R HN +A L LN W + ++ AR +V A H + +++P +LG +
Sbjct: 404 TALHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEA 462
Query: 254 MIEDEIILCNSTGFRDIYDETVVPQIALEYAYAS-RWFHTIQYGAQKLFDKNFNFIKEVP 312
+ G + YD T P ++ ++ A+ R+ H + + D +F ++P
Sbjct: 463 FQQ-------YVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLP 515
Query: 313 ---MVNFTLSVQSLAVGDIMSTVTRGSYYQAT--GKGDSSVDPDITD-VGLGPVQEIFDI 366
+ S +L G + + RG + D ++ ++T+ + + ++
Sbjct: 516 GLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLNL 575
Query: 367 PTADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQLKQVYETAEDIEL 426
+ +L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I++
Sbjct: 576 ASINLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNIDV 634
Query: 427 MAEQLQE---IRKASLALLLCYVGDDVEKIQ 454
L E R + L C +G ++ ++
Sbjct: 635 WLGGLAENFLPRARTGPLFACLIGKQMKALR 665
>S36219-1|AAB22216.1| 562|Homo sapiens prostaglandin G/H synthase
protein.
Length = 562
Score = 57.6 bits (133), Expect = 9e-08
Identities = 37/126 (29%), Positives = 63/126 (50%), Gaps = 5/126 (3%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCF-IKQAISTGCTRTVP 188
DL +IY + Q+R ++ G+LKY+V++G +P + + I V
Sbjct: 228 DLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVG 287
Query: 189 N---GIL-GTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
G+L G L+ T + R HN V L +P+W DEQLF T R I++ +++ E+
Sbjct: 288 QEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEY 347
Query: 245 LPEVLG 250
+ ++ G
Sbjct: 348 VQQLSG 353
>AL359636-7|CAM45740.1| 562|Homo sapiens prostaglandin-endoperoxide
synthase 1 (prostaglandin G/H synthase and cyclooxyg
protein.
Length = 562
Score = 57.6 bits (133), Expect = 9e-08
Identities = 37/126 (29%), Positives = 63/126 (50%), Gaps = 5/126 (3%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCF-IKQAISTGCTRTVP 188
DL +IY + Q+R ++ G+LKY+V++G +P + + I V
Sbjct: 228 DLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVG 287
Query: 189 N---GIL-GTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
G+L G L+ T + R HN V L +P+W DEQLF T R I++ +++ E+
Sbjct: 288 QEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEY 347
Query: 245 LPEVLG 250
+ ++ G
Sbjct: 348 VQQLSG 353
>AL162424-12|CAI14714.1| 562|Homo sapiens
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H
synthase and cyclooxyg protein.
Length = 562
Score = 57.6 bits (133), Expect = 9e-08
Identities = 37/126 (29%), Positives = 63/126 (50%), Gaps = 5/126 (3%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCF-IKQAISTGCTRTVP 188
DL +IY + Q+R ++ G+LKY+V++G +P + + I V
Sbjct: 228 DLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVG 287
Query: 189 N---GIL-GTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
G+L G L+ T + R HN V L +P+W DEQLF T R I++ +++ E+
Sbjct: 288 QEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEY 347
Query: 245 LPEVLG 250
+ ++ G
Sbjct: 348 VQQLSG 353
>AY151286-1|AAN52932.1| 339|Homo sapiens cyclooxygenase 2b protein.
Length = 339
Score = 56.0 bits (129), Expect = 3e-07
Identities = 32/122 (26%), Positives = 57/122 (46%), Gaps = 5/122 (4%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFPSDASDNTTCFI-----KQAISTGCT 184
DL++IY + ++R ++ G++KY++++G +P D I + +
Sbjct: 215 DLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVG 274
Query: 185 RTVPNGILGTNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEF 244
+ V + G ++ T + R HN V L +P W DEQLF T+R I++ Y
Sbjct: 275 QEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGKQENDLYKTL 334
Query: 245 LP 246
P
Sbjct: 335 FP 336
>BC009496-1|AAH09496.2| 218|Homo sapiens PXDN protein protein.
Length = 218
Score = 44.0 bits (99), Expect = 0.001
Identities = 18/53 (33%), Positives = 32/53 (60%)
Query: 431 LQEIRKASLALLLCYVGDDVEKIQPNPFVIVGKGNNLVSCDEIPAIDFTYWKE 483
L +I++ SLA +LC D++ ++Q + F + + SCDEIP +D W++
Sbjct: 2 LTQIKQTSLARILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQD 54
>X17358-1|CAA35235.1| 876|Homo sapiens protein ( Human mRNA from
alternatively spliced TPO-2 gene for thyroid peroxidase
(EC.1.11.1.7). ).
Length = 876
Score = 42.7 bits (96), Expect = 0.003
Identities = 31/120 (25%), Positives = 55/120 (45%), Gaps = 9/120 (7%)
Query: 194 TNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDH 253
T L T W R HN +A L LN W + ++ AR +V A H + +++P +LG +
Sbjct: 404 TALHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEA 462
Query: 254 MIEDEIILCNSTGFRDIYDETVVPQIALEYAYAS-RWFHTIQYGAQKLFDKNFNFIKEVP 312
+ G + YD T P ++ ++ A+ R+ H + + D +F ++P
Sbjct: 463 FQQ-------YVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLP 515
>J02970-1|AAA61216.1| 876|Homo sapiens TPO protein.
Length = 876
Score = 42.7 bits (96), Expect = 0.003
Identities = 31/120 (25%), Positives = 55/120 (45%), Gaps = 9/120 (7%)
Query: 194 TNLFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMFYYEFLPEVLGKDH 253
T L T W R HN +A L LN W + ++ AR +V A H + +++P +LG +
Sbjct: 404 TALHTLWL-REHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEA 462
Query: 254 MIEDEIILCNSTGFRDIYDETVVPQIALEYAYAS-RWFHTIQYGAQKLFDKNFNFIKEVP 312
+ G + YD T P ++ ++ A+ R+ H + + D +F ++P
Sbjct: 463 FQQ-------YVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLP 515
>BC051850-1|AAH51850.1| 343|Homo sapiens transmembrane protein
induced by tumor necrosis factor alpha protein.
Length = 343
Score = 35.5 bits (78), Expect = 0.42
Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Query: 183 CTRTVPNGILGTN--LFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMF 240
CT T+ IL N W W FH+YV+ L+ + +W D ++ R+ ++F +
Sbjct: 173 CTLTIRESILINNGSRIKGW-WVFHHYVSAFLSGVMLTWPDGLMYQKFRNQFLSFSMYQS 231
Query: 241 YYEFL 245
+ +FL
Sbjct: 232 FVQFL 236
>AF439430-1|AAL74416.1| 760|Homo sapiens thyroid peroxidase
protein.
Length = 760
Score = 35.5 bits (78), Expect = 0.42
Identities = 23/93 (24%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Query: 365 DIPTADLAKGRYFGLPSYTKYRDFCSGYSKKHVDFDDLTDHISDEKIRQLKQVYETAEDI 424
D+ + +L +GR GLP Y ++R+FC G + D T S ++ +Y+ ++I
Sbjct: 401 DLASINLQRGRDHGLPGYNEWREFC-GLPRLETPADLSTAIASRSVADKILDLYKHPDNI 459
Query: 425 ELMAEQLQE---IRKASLALLLCYVGDDVEKIQ 454
++ L E R + L C +G ++ ++
Sbjct: 460 DVWLGGLAENFLPRARTGPLFACLIGKQMKALR 492
>AF327923-1|AAK16442.1| 343|Homo sapiens transmembrane protein
induced by tumor necrosis factor alpha protein.
Length = 343
Score = 35.5 bits (78), Expect = 0.42
Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Query: 183 CTRTVPNGILGTN--LFTTWFWRFHNYVAQQLANLNPSWDDEQLFYTARDIVVAFHLQMF 240
CT T+ IL N W W FH+YV+ L+ + +W D ++ R+ ++F +
Sbjct: 173 CTLTIRESILINNGSRIKGW-WVFHHYVSTFLSGVMLTWPDGLMYQKFRNQFLSFSMYQS 231
Query: 241 YYEFL 245
+ +FL
Sbjct: 232 FVQFL 236
>AL162424-13|CAI14716.1| 156|Homo sapiens
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H
synthase and cyclooxyg protein.
Length = 156
Score = 31.9 bits (69), Expect = 5.2
Identities = 13/35 (37%), Positives = 23/35 (65%)
Query: 130 DLSNIYEFSAGSLNQVRSYEGGQLKYEVVNGRQFP 164
DL +IY + Q+R ++ G+LKY+V++G +P
Sbjct: 122 DLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYP 156
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.137 0.419
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 72,945,585
Number of Sequences: 224733
Number of extensions: 3147956
Number of successful extensions: 5800
Number of sequences better than 10.0: 67
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 5612
Number of HSP's gapped (non-prelim): 119
length of query: 485
length of database: 73,234,838
effective HSP length: 93
effective length of query: 392
effective length of database: 52,334,669
effective search space: 20515190248
effective search space used: 20515190248
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 67 (31.1 bits)
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