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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000222-TA|BGIBMGA000222-PA|IPR006603|Cystinosin/ERS1p
repeat, IPR005282|Lysosomal cystine transporter
         (566 letters)

Database: fruitfly 
           52,641 sequences; 24,830,863 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AY119096-1|AAM50956.1|  397|Drosophila melanogaster LP12305p pro...   405   e-113
AE014297-3262|AAF56088.2|  397|Drosophila melanogaster CG17119-P...   405   e-113
AE014297-3263|AAO41592.1|  363|Drosophila melanogaster CG17119-P...   402   e-112
AE013599-3457|AAF46894.2| 1227|Drosophila melanogaster CG30268-P...    33   1.4  
AE014134-408|AAF51254.1|  348|Drosophila melanogaster CG18641-PA...    30   9.8  

>AY119096-1|AAM50956.1|  397|Drosophila melanogaster LP12305p
           protein.
          Length = 397

 Score =  405 bits (997), Expect = e-113
 Identities = 194/380 (51%), Positives = 264/380 (69%), Gaps = 7/380 (1%)

Query: 120 SSHRIRFCLVVMLILGIPSAHSQLDKMYVEVTDLNLLVEETRLLKLVQIGQYNTSLEVIS 179
           S+HR+   L+++L+  +   ++Q  ++ V+  D+ +L+       +   G  ++ +EV  
Sbjct: 4   STHRLT-TLLLLLLATVALGNAQSSQLTVDSHDITVLLNSNETFLVFANGLLDSDVEVAL 62

Query: 180 NIQHPDIVQLVPPSIEIPGSNEPNKTVVISYDICAYGKSPGHSEVTFNVTPPGFVNLDTV 239
                D + L P +   P  +  N++VVI+      G   G+ +V  +        +  V
Sbjct: 63  GTDSEDHLLLDPATFVYPAGSTRNQSVVIT------GLKAGNVKVVADSDDANKEIVKDV 116

Query: 240 YLRITVMHSNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFT 299
           ++R+TV  S  +   S I GW+YF AWSVSFYPQI+ N++RKSV GLNFDFLALNI+GFT
Sbjct: 117 FVRVTVAKSRALIYTSIIFGWVYFVAWSVSFYPQIWSNYRRKSVEGLNFDFLALNIVGFT 176

Query: 300 MYSLFNCGLYFSKEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQ 359
           +YS+FNCGLYF +++QNEY  R+P G+NPV LNDV FSLHA FAT ITI QCF Y+R +Q
Sbjct: 177 LYSMFNCGLYFIEDLQNEYEVRYPLGVNPVMLNDVVFSLHAMFATCITILQCFFYQRAQQ 236

Query: 360 RVSTVGRGILGAFSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKR 419
           RVS +  GIL  F+ VV+V+  +A    I WLD+LYYCSYVKL IT+IKYVPQA MNY+R
Sbjct: 237 RVSFIAYGILAIFAVVVVVSAGLAGGSVIHWLDFLYYCSYVKLTITIIKYVPQALMNYRR 296

Query: 420 KSTVGWSIGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDIFFIL 479
           KST GWSIGNI LDF GG LS+LQM+LNA+NY+DWVS FGD TKFGLGLFS++FD+FF+L
Sbjct: 297 KSTSGWSIGNILLDFTGGTLSMLQMILNAHNYDDWVSIFGDPTKFGLGLFSVLFDVFFML 356

Query: 480 QHYVFYRNADKKYNLDVKSL 499
           QHYVFYR++ +  + D+ ++
Sbjct: 357 QHYVFYRHSRESSSSDLTTV 376


>AE014297-3262|AAF56088.2|  397|Drosophila melanogaster CG17119-PA,
           isoform A protein.
          Length = 397

 Score =  405 bits (997), Expect = e-113
 Identities = 194/380 (51%), Positives = 264/380 (69%), Gaps = 7/380 (1%)

Query: 120 SSHRIRFCLVVMLILGIPSAHSQLDKMYVEVTDLNLLVEETRLLKLVQIGQYNTSLEVIS 179
           S+HR+   L+++L+  +   ++Q  ++ V+  D+ +L+       +   G  ++ +EV  
Sbjct: 4   STHRLT-TLLLLLLATVALGNAQSSQLTVDSHDITVLLNSNETFLVFANGLLDSDVEVAL 62

Query: 180 NIQHPDIVQLVPPSIEIPGSNEPNKTVVISYDICAYGKSPGHSEVTFNVTPPGFVNLDTV 239
                D + L P +   P  +  N++VVI+      G   G+ +V  +        +  V
Sbjct: 63  GTDSEDHLLLDPATFVYPAGSTRNQSVVIT------GLKAGNVKVVADSDDANKEIVKDV 116

Query: 240 YLRITVMHSNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFT 299
           ++R+TV  S  +   S I GW+YF AWSVSFYPQI+ N++RKSV GLNFDFLALNI+GFT
Sbjct: 117 FVRVTVAKSRALIYTSIIFGWVYFVAWSVSFYPQIWSNYRRKSVEGLNFDFLALNIVGFT 176

Query: 300 MYSLFNCGLYFSKEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQ 359
           +YS+FNCGLYF +++QNEY  R+P G+NPV LNDV FSLHA FAT ITI QCF Y+R +Q
Sbjct: 177 LYSMFNCGLYFIEDLQNEYEVRYPLGVNPVMLNDVVFSLHAMFATCITILQCFFYQRAQQ 236

Query: 360 RVSTVGRGILGAFSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKR 419
           RVS +  GIL  F+ VV+V+  +A    I WLD+LYYCSYVKL IT+IKYVPQA MNY+R
Sbjct: 237 RVSFIAYGILAIFAVVVVVSAGLAGGSVIHWLDFLYYCSYVKLTITIIKYVPQALMNYRR 296

Query: 420 KSTVGWSIGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDIFFIL 479
           KST GWSIGNI LDF GG LS+LQM+LNA+NY+DWVS FGD TKFGLGLFS++FD+FF+L
Sbjct: 297 KSTSGWSIGNILLDFTGGTLSMLQMILNAHNYDDWVSIFGDPTKFGLGLFSVLFDVFFML 356

Query: 480 QHYVFYRNADKKYNLDVKSL 499
           QHYVFYR++ +  + D+ ++
Sbjct: 357 QHYVFYRHSRESSSSDLTTV 376


>AE014297-3263|AAO41592.1|  363|Drosophila melanogaster CG17119-PB,
           isoform B protein.
          Length = 363

 Score =  402 bits (991), Expect = e-112
 Identities = 193/367 (52%), Positives = 256/367 (69%), Gaps = 7/367 (1%)

Query: 120 SSHRIRFCLVVMLILGIPSAHSQLDKMYVEVTDLNLLVEETRLLKLVQIGQYNTSLEVIS 179
           S+HR+   L+++L+  +   ++Q  ++ V+  D+ +L+       +   G  ++ +EV  
Sbjct: 4   STHRLT-TLLLLLLATVALGNAQSSQLTVDSHDITVLLNSNETFLVFANGLLDSDVEVAL 62

Query: 180 NIQHPDIVQLVPPSIEIPGSNEPNKTVVISYDICAYGKSPGHSEVTFNVTPPGFVNLDTV 239
                D + L P +   P  +  N++VVI+      G   G+ +V  +        +  V
Sbjct: 63  GTDSEDHLLLDPATFVYPAGSTRNQSVVIT------GLKAGNVKVVADSDDANKEIVKDV 116

Query: 240 YLRITVMHSNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFT 299
           ++R+TV  S  +   S I GW+YF AWSVSFYPQI+ N++RKSV GLNFDFLALNI+GFT
Sbjct: 117 FVRVTVAKSRALIYTSIIFGWVYFVAWSVSFYPQIWSNYRRKSVEGLNFDFLALNIVGFT 176

Query: 300 MYSLFNCGLYFSKEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQ 359
           +YS+FNCGLYF +++QNEY  R+P G+NPV LNDV FSLHA FAT ITI QCF Y+R +Q
Sbjct: 177 LYSMFNCGLYFIEDLQNEYEVRYPLGVNPVMLNDVVFSLHAMFATCITILQCFFYQRAQQ 236

Query: 360 RVSTVGRGILGAFSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKR 419
           RVS +  GIL  F+ VV+V+  +A    I WLD+LYYCSYVKL IT+IKYVPQA MNY+R
Sbjct: 237 RVSFIAYGILAIFAVVVVVSAGLAGGSVIHWLDFLYYCSYVKLTITIIKYVPQALMNYRR 296

Query: 420 KSTVGWSIGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDIFFIL 479
           KST GWSIGNI LDF GG LS+LQM+LNA+NY+DWVS FGD TKFGLGLFS++FD+FF+L
Sbjct: 297 KSTSGWSIGNILLDFTGGTLSMLQMILNAHNYDDWVSIFGDPTKFGLGLFSVLFDVFFML 356

Query: 480 QHYVFYR 486
           QHYVFYR
Sbjct: 357 QHYVFYR 363


>AE013599-3457|AAF46894.2| 1227|Drosophila melanogaster CG30268-PA
           protein.
          Length = 1227

 Score = 32.7 bits (71), Expect = 1.4
 Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 1/63 (1%)

Query: 129 VVMLILGIPSAHSQLDKMYVE-VTDLNLLVEETRLLKLVQIGQYNTSLEVISNIQHPDIV 187
           +VM  LGIP   S+LD + +E + DL + +  +       + Q N ++E +  I HP   
Sbjct: 891 IVMEDLGIPEKDSRLDPIILEMIADLGVTIYLSTNYSQFILSQDNMNIEKVELIMHPSKK 950

Query: 188 QLV 190
           ++V
Sbjct: 951 KIV 953


>AE014134-408|AAF51254.1|  348|Drosophila melanogaster CG18641-PA
           protein.
          Length = 348

 Score = 29.9 bits (64), Expect = 9.8
 Identities = 12/30 (40%), Positives = 20/30 (66%)

Query: 317 EYFSRHPRGLNPVQLNDVFFSLHAAFATLI 346
           +Y +RHPRG+ P  L+ + +S+ A  A L+
Sbjct: 148 KYLARHPRGVQPDDLHFIGYSVGAHIAGLV 177


  Database: fruitfly
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 24,830,863
  Number of sequences in database:  52,641
  
Lambda     K      H
   0.325    0.139    0.432 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 26,162,973
Number of Sequences: 52641
Number of extensions: 1048358
Number of successful extensions: 3377
Number of sequences better than 10.0: 5
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 3366
Number of HSP's gapped (non-prelim): 6
length of query: 566
length of database: 24,830,863
effective HSP length: 89
effective length of query: 477
effective length of database: 20,145,814
effective search space: 9609553278
effective search space used: 9609553278
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.6 bits)
S2: 64 (29.9 bits)

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