BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000222-TA|BGIBMGA000222-PA|IPR006603|Cystinosin/ERS1p repeat, IPR005282|Lysosomal cystine transporter (566 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_UPI00015B606B Cluster: PREDICTED: similar to LP12305p; ... 409 e-112 UniRef50_Q9VCR7 Cluster: Cystinosin homolog; n=3; Sophophora|Rep... 405 e-111 UniRef50_Q177J0 Cluster: Cystinosin; n=6; Endopterygota|Rep: Cys... 387 e-106 UniRef50_Q17HW4 Cluster: Cystinosin; n=3; Culicidae|Rep: Cystino... 305 1e-81 UniRef50_O60931 Cluster: Cystinosin; n=27; Eumetazoa|Rep: Cystin... 302 2e-80 UniRef50_Q09500 Cluster: Cystinosin homolog; n=3; Caenorhabditis... 294 4e-78 UniRef50_UPI0000E4776A Cluster: PREDICTED: similar to cystinosin... 269 2e-70 UniRef50_Q54WT7 Cluster: Putative uncharacterized protein; n=1; ... 267 6e-70 UniRef50_P57758 Cluster: Cystinosin homolog; n=9; Magnoliophyta|... 228 3e-58 UniRef50_Q4DCC2 Cluster: Cystinosin, putative; n=2; Trypanosoma ... 220 9e-56 UniRef50_A2Q8N4 Cluster: Function: human CTNS is a lysosomal cys... 204 6e-51 UniRef50_UPI0000DA2024 Cluster: PREDICTED: similar to Cystinosin... 201 3e-50 UniRef50_Q4SRV7 Cluster: Chromosome undetermined SCAF14488, whol... 201 5e-50 UniRef50_Q7S781 Cluster: Related to CTNS protein [MIPS]; n=5; Pe... 196 1e-48 UniRef50_Q4P2H9 Cluster: Putative uncharacterized protein; n=1; ... 193 9e-48 UniRef50_A6R572 Cluster: Putative uncharacterized protein; n=1; ... 190 9e-47 UniRef50_A7SMR9 Cluster: Predicted protein; n=2; Nematostella ve... 187 8e-46 UniRef50_A1CUZ4 Cluster: L-cystine transporter, putative; n=4; T... 175 2e-42 UniRef50_A0C517 Cluster: Chromosome undetermined scaffold_15, wh... 171 6e-41 UniRef50_UPI00006D0016 Cluster: PQ loop repeat family protein; n... 157 6e-37 UniRef50_A0NH14 Cluster: ENSANGP00000023811; n=1; Anopheles gamb... 149 1e-34 UniRef50_A0DZ98 Cluster: Chromosome undetermined scaffold_7, who... 145 2e-33 UniRef50_A6SSL3 Cluster: H+ driven lysosomal cystine transporter... 121 4e-26 UniRef50_Q5KPP2 Cluster: L-cystine transporter, putative; n=2; F... 118 3e-25 UniRef50_Q5C2M8 Cluster: SJCHGC09199 protein; n=1; Schistosoma j... 111 5e-23 UniRef50_P17261 Cluster: Cystine transporter; n=4; Saccharomycet... 96 2e-18 UniRef50_Q756J2 Cluster: AER269Cp; n=1; Eremothecium gossypii|Re... 94 8e-18 UniRef50_Q6CID8 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 83 2e-14 UniRef50_Q54JY3 Cluster: Putative uncharacterized protein; n=1; ... 56 3e-06 UniRef50_Q6C2U6 Cluster: Similar to tr|Q12010 Saccharomyces cere... 51 9e-05 UniRef50_Q5AFJ5 Cluster: Putative uncharacterized protein; n=1; ... 50 2e-04 UniRef50_A3LX51 Cluster: Mannosyltransferase; n=5; Saccharomycet... 49 4e-04 UniRef50_Q54F66 Cluster: Putative uncharacterized protein; n=1; ... 48 9e-04 UniRef50_Q6FL26 Cluster: Candida glabrata strain CBS138 chromoso... 44 0.011 UniRef50_A7THU6 Cluster: Putative uncharacterized protein; n=1; ... 44 0.011 UniRef50_A5DZI3 Cluster: Putative uncharacterized protein; n=1; ... 43 0.025 UniRef50_A3M0K0 Cluster: Predicted protein; n=1; Pichia stipitis... 43 0.025 UniRef50_Q7RZR4 Cluster: Putative uncharacterized protein NCU003... 42 0.058 UniRef50_P38279 Cluster: Uncharacterized membrane protein YBR147... 42 0.058 UniRef50_Q6ZP29 Cluster: PQ-loop repeat-containing protein 2; n=... 42 0.058 UniRef50_UPI00005A038F Cluster: PREDICTED: similar to PQ loop re... 41 0.076 UniRef50_Q2H971 Cluster: Putative uncharacterized protein; n=6; ... 41 0.076 UniRef50_Q95XZ6 Cluster: Putative uncharacterized protein Y43H11... 41 0.10 UniRef50_Q75CM5 Cluster: ACL106Cp; n=1; Eremothecium gossypii|Re... 40 0.18 UniRef50_A2EVI6 Cluster: Putative uncharacterized protein; n=1; ... 40 0.23 UniRef50_Q6CMA9 Cluster: Similar to sgd|S0002760 Saccharomyces c... 39 0.31 UniRef50_Q12010 Cluster: Uncharacterized membrane protein YOL092... 39 0.31 UniRef50_Q8RXY4 Cluster: Putative uncharacterized protein At2g41... 39 0.41 UniRef50_A7PTI6 Cluster: Chromosome chr8 scaffold_29, whole geno... 39 0.41 UniRef50_Q245B2 Cluster: Dual specificity phosphatase, catalytic... 39 0.41 UniRef50_Q5A6A9 Cluster: Putative uncharacterized protein; n=2; ... 39 0.41 UniRef50_Q4WET1 Cluster: PQ loop repeat protein; n=3; Trichocoma... 38 0.54 UniRef50_A6RRJ7 Cluster: Putative uncharacterized protein; n=1; ... 38 0.54 UniRef50_UPI0000510461 Cluster: COG0463: Glycosyltransferases in... 38 0.71 UniRef50_A7NA75 Cluster: PQ loop repeat family; n=11; Francisell... 38 0.71 UniRef50_A2F7R5 Cluster: PQ loop repeat family protein; n=1; Tri... 38 0.71 UniRef50_Q0IHH3 Cluster: MGC154351 protein; n=6; Xenopus|Rep: MG... 38 0.94 UniRef50_A2QUR4 Cluster: Contig An09c0220, complete genome; n=2;... 38 0.94 UniRef50_Q10482 Cluster: Seven transmembrane protein 1; n=1; Sch... 38 0.94 UniRef50_UPI000049838B Cluster: PQ loop repeat protein; n=1; Ent... 37 1.2 UniRef50_O49437 Cluster: Putative uncharacterized protein AT4g20... 37 1.2 UniRef50_A2WN84 Cluster: Putative uncharacterized protein; n=2; ... 37 1.2 UniRef50_Q7QXS6 Cluster: GLP_77_47661_46030; n=1; Giardia lambli... 37 1.2 UniRef50_Q6BRI2 Cluster: Similar to CA4714|IPF5912 Candida albic... 37 1.2 UniRef50_Q8C4N4 Cluster: PQ-loop repeat-containing protein 2; n=... 37 1.2 UniRef50_A1L2M0 Cluster: LOC100036889 protein; n=2; Tetrapoda|Re... 36 2.2 UniRef50_A2ETQ8 Cluster: PQ loop repeat family protein; n=2; Tri... 36 2.2 UniRef50_A2GEV7 Cluster: Putative uncharacterized protein; n=1; ... 36 2.9 UniRef50_A2FTR9 Cluster: Putative uncharacterized protein; n=1; ... 36 2.9 UniRef50_A2FKL1 Cluster: PQ loop repeat family protein; n=2; Tri... 36 2.9 UniRef50_Q870T0 Cluster: Putative uncharacterized protein B1D14.... 36 2.9 UniRef50_A7TKY0 Cluster: Putative uncharacterized protein; n=1; ... 36 2.9 UniRef50_A6QV92 Cluster: Predicted protein; n=1; Ajellomyces cap... 36 2.9 UniRef50_Q2FLF8 Cluster: Putative uncharacterized protein; n=1; ... 36 2.9 UniRef50_UPI000023E534 Cluster: hypothetical protein FG08496.1; ... 36 3.8 UniRef50_Q0IHB9 Cluster: LOC779076 protein; n=5; Tetrapoda|Rep: ... 36 3.8 UniRef50_Q1N3L8 Cluster: Putative uncharacterized protein; n=1; ... 36 3.8 UniRef50_Q01G95 Cluster: Vacuolar-type H+-pyrophosphatase; n=4; ... 36 3.8 UniRef50_Q54C20 Cluster: Putative uncharacterized protein; n=1; ... 36 3.8 UniRef50_UPI00006CF828 Cluster: Protein kinase domain containing... 35 5.0 UniRef50_Q5C6I4 Cluster: SJCHGC07693 protein; n=1; Schistosoma j... 35 5.0 UniRef50_Q4D0H0 Cluster: Putative uncharacterized protein; n=2; ... 35 5.0 UniRef50_Q1DKV8 Cluster: Putative uncharacterized protein; n=1; ... 35 5.0 UniRef50_A3LPY7 Cluster: Predicted protein; n=3; Saccharomycetac... 35 5.0 UniRef50_Q9KBB5 Cluster: Sensor protein; n=1; Bacillus haloduran... 35 6.6 UniRef50_Q8VSZ3 Cluster: AgrC; n=2; Staphylococcus caprae|Rep: A... 35 6.6 UniRef50_A7PV16 Cluster: Chromosome chr4 scaffold_32, whole geno... 35 6.6 UniRef50_Q1EQ45 Cluster: EhSec24D; n=2; Entamoeba histolytica|Re... 35 6.6 UniRef50_A5K509 Cluster: PQ loop repeat family protein; n=1; Pla... 35 6.6 UniRef50_A3GHF7 Cluster: Putative uncharacterized protein; n=1; ... 35 6.6 UniRef50_UPI0000E47FB1 Cluster: PREDICTED: hypothetical protein,... 34 8.8 UniRef50_UPI0000499C8C Cluster: hypothetical protein 168.t00007;... 34 8.8 UniRef50_Q9RS20 Cluster: Multidrug-efflux transporter, putative;... 34 8.8 UniRef50_A4CAG3 Cluster: Putative uncharacterized protein; n=1; ... 34 8.8 UniRef50_A4RW10 Cluster: Predicted protein; n=1; Ostreococcus lu... 34 8.8 UniRef50_Q7RE63 Cluster: Putative uncharacterized protein PY0520... 34 8.8 UniRef50_A2EC37 Cluster: Putative uncharacterized protein; n=1; ... 34 8.8 UniRef50_Q6CAK3 Cluster: Similar to tr|Q06328 Saccharomyces cere... 34 8.8 UniRef50_Q08022 Cluster: Inner membrane protein yjgN; n=10; Ente... 34 8.8 UniRef50_P34856 Cluster: NADH-ubiquinone oxidoreductase chain 6;... 34 8.8 >UniRef50_UPI00015B606B Cluster: PREDICTED: similar to LP12305p; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to LP12305p - Nasonia vitripennis Length = 1165 Score = 409 bits (1007), Expect = e-112 Identities = 198/374 (52%), Positives = 269/374 (71%), Gaps = 12/374 (3%) Query: 128 LVVMLILGIPSAHSQLDKMYVEVTDLNLLVEETRLLKLVQIGQYNTS-LEVISNIQHPDI 186 L+++L+L + A ++ V V D+ ++ + L + T+ E+ QH D+ Sbjct: 803 LLMLLLLAVGGATAEYR---VSVQDIRVIHKARNHFFLYTTEKNRTADTEIFFESQHVDL 859 Query: 187 VQLVPPSIEIPGSNEPNKTVVISYDICAYGKSPGHSEVTFNVTPPGFVNLDTVYLRITVM 246 V+ P I +E N T+ I G +PG++ ++ NV+ + +LR+TV Sbjct: 860 VRTEPAHF-IAKKDEYNWTIEI------LGLNPGNALISTNVSGADPSDFSDAFLRVTVE 912 Query: 247 HSNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNC 306 S+ + +S ++GWIYF AWS+SFYPQI+ N+KRKSVVGLNFD+L+LN++GF MY+LFNC Sbjct: 913 RSDTLYHVSAVVGWIYFLAWSISFYPQIHSNYKRKSVVGLNFDYLSLNLVGFIMYALFNC 972 Query: 307 GLYFSKEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQRVSTVGR 366 GLY+ EI+ EYFSR+P+GLNPVQ+ND+FF+LHA ATL+TI QCF+YE QRVST R Sbjct: 973 GLYWIPEIEQEYFSRYPKGLNPVQVNDIFFALHAVCATLVTIVQCFIYETGTQRVSTTAR 1032 Query: 367 GILGAFSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWS 426 I G FS+ V+++ +A++ I+WLD+LYYCSYVKLAITLIKYVPQA+ NYKRKSTVGWS Sbjct: 1033 IIHGIFSSFVLISVILAILHVIQWLDFLYYCSYVKLAITLIKYVPQAFYNYKRKSTVGWS 1092 Query: 427 IGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDIFFILQHYVFYR 486 IGNIFLDF GG LS+LQM+LNAYNY+DW S FGD TKFGLG FS+ FDIFF++QHYV YR Sbjct: 1093 IGNIFLDFTGGVLSMLQMILNAYNYDDWESIFGDPTKFGLGFFSVAFDIFFLVQHYVLYR 1152 Query: 487 NADKKYNLDVKSLI 500 + ++K +D+K + Sbjct: 1153 HTNEK-EIDLKGRV 1165 >UniRef50_Q9VCR7 Cluster: Cystinosin homolog; n=3; Sophophora|Rep: Cystinosin homolog - Drosophila melanogaster (Fruit fly) Length = 397 Score = 405 bits (997), Expect = e-111 Identities = 194/380 (51%), Positives = 264/380 (69%), Gaps = 7/380 (1%) Query: 120 SSHRIRFCLVVMLILGIPSAHSQLDKMYVEVTDLNLLVEETRLLKLVQIGQYNTSLEVIS 179 S+HR+ L+++L+ + ++Q ++ V+ D+ +L+ + G ++ +EV Sbjct: 4 STHRLT-TLLLLLLATVALGNAQSSQLTVDSHDITVLLNSNETFLVFANGLLDSDVEVAL 62 Query: 180 NIQHPDIVQLVPPSIEIPGSNEPNKTVVISYDICAYGKSPGHSEVTFNVTPPGFVNLDTV 239 D + L P + P + N++VVI+ G G+ +V + + V Sbjct: 63 GTDSEDHLLLDPATFVYPAGSTRNQSVVIT------GLKAGNVKVVADSDDANKEIVKDV 116 Query: 240 YLRITVMHSNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFT 299 ++R+TV S + S I GW+YF AWSVSFYPQI+ N++RKSV GLNFDFLALNI+GFT Sbjct: 117 FVRVTVAKSRALIYTSIIFGWVYFVAWSVSFYPQIWSNYRRKSVEGLNFDFLALNIVGFT 176 Query: 300 MYSLFNCGLYFSKEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQ 359 +YS+FNCGLYF +++QNEY R+P G+NPV LNDV FSLHA FAT ITI QCF Y+R +Q Sbjct: 177 LYSMFNCGLYFIEDLQNEYEVRYPLGVNPVMLNDVVFSLHAMFATCITILQCFFYQRAQQ 236 Query: 360 RVSTVGRGILGAFSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKR 419 RVS + GIL F+ VV+V+ +A I WLD+LYYCSYVKL IT+IKYVPQA MNY+R Sbjct: 237 RVSFIAYGILAIFAVVVVVSAGLAGGSVIHWLDFLYYCSYVKLTITIIKYVPQALMNYRR 296 Query: 420 KSTVGWSIGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDIFFIL 479 KST GWSIGNI LDF GG LS+LQM+LNA+NY+DWVS FGD TKFGLGLFS++FD+FF+L Sbjct: 297 KSTSGWSIGNILLDFTGGTLSMLQMILNAHNYDDWVSIFGDPTKFGLGLFSVLFDVFFML 356 Query: 480 QHYVFYRNADKKYNLDVKSL 499 QHYVFYR++ + + D+ ++ Sbjct: 357 QHYVFYRHSRESSSSDLTTV 376 >UniRef50_Q177J0 Cluster: Cystinosin; n=6; Endopterygota|Rep: Cystinosin - Aedes aegypti (Yellowfever mosquito) Length = 406 Score = 387 bits (953), Expect = e-106 Identities = 174/340 (51%), Positives = 249/340 (73%), Gaps = 6/340 (1%) Query: 152 DLNLLVEETRLLKLVQIGQYNTSLEVISNIQHPDIVQLVPP--SIEIPGSNEPNKTVVIS 209 D+++LV+ET+ +++ GQ +++ + +H + V + P S++ P + +K V + Sbjct: 36 DISVLVQETKDIQVRFRGQLTQNVQFNFSNEHSEFVTVTPSVISVDAPSNGFIDKAVPVK 95 Query: 210 YDICAYGKSPGHSEVTFNVTPPGFVNLDTVYLRITVMHSNEINIISYIMGWIYFAAWSVS 269 SPG ++ + P G ++ ++R+T+ +S I +S ++GWIYF AW++S Sbjct: 96 LQAL----SPGQFDLVGKIIPAGLIDDAKAFIRVTIANSTAIIYVSIVIGWIYFVAWTIS 151 Query: 270 FYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLYFSKEIQNEYFSRHPRGLNPV 329 F+PQ+ INF+RKSVVGL+FDFLA+N++G T+Y++FNC LY++ I+ EYF+R+PRGLNPV Sbjct: 152 FWPQMIINFRRKSVVGLSFDFLAMNLLGHTLYAIFNCSLYWNDHIEQEYFNRNPRGLNPV 211 Query: 330 QLNDVFFSLHAAFATLITITQCFLYEREEQRVSTVGRGILGAFSAVVIVTGSIAVVGKIE 389 NDV FSLHA+ AT +T+ QCFLYER EQRVS +GILG F+ +++V+G + Sbjct: 212 IANDVAFSLHASLATFLTVVQCFLYERGEQRVSYTAQGILGVFATIIVVSGILVGTETWH 271 Query: 390 WLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNAY 449 WLD+LY SY+KLAITLIKYVPQA +N++RKSTVGWSI NI LDF GG LS+LQM+LNAY Sbjct: 272 WLDFLYALSYIKLAITLIKYVPQAVLNFRRKSTVGWSIENILLDFTGGMLSMLQMLLNAY 331 Query: 450 NYNDWVSFFGDATKFGLGLFSLVFDIFFILQHYVFYRNAD 489 NY+DW S FGD TKFGLGLFS++FDI FI+QHYV Y++++ Sbjct: 332 NYDDWASIFGDPTKFGLGLFSVLFDIVFIVQHYVLYKDSE 371 >UniRef50_Q17HW4 Cluster: Cystinosin; n=3; Culicidae|Rep: Cystinosin - Aedes aegypti (Yellowfever mosquito) Length = 367 Score = 305 bits (750), Expect = 1e-81 Identities = 142/300 (47%), Positives = 199/300 (66%), Gaps = 3/300 (1%) Query: 187 VQLVPPSIEIPGSNEPNKTVVISYDICAYGKSPGHSEVTFNVTPPGFVNLDTVYLRITVM 246 V + P + I G + +T ++ + A G G V V P G + +++R+ V Sbjct: 68 VSVTPDQLWINGGVKYTETPIV---VSAKGLRQGRFIVEAGVEPEGIADDRRLFVRLKVA 124 Query: 247 HSNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNC 306 + + IS ++GW Y A WS+ +YPQI +N++RKSVVGL+FDFL +NI+G Y+ FN Sbjct: 125 LNQPLIYISLVIGWAYTACWSIGYYPQIILNYQRKSVVGLSFDFLHINIIGHVCYAFFNS 184 Query: 307 GLYFSKEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQRVSTVGR 366 +Y++ I+ EYF RHP GLNPV NDV F++HA+ AT TI QC++Y+ VS + Sbjct: 185 FMYWNSFIEKEYFDRHPHGLNPVIGNDVGFAVHASVATGYTILQCYIYQSNGNTVSPTAK 244 Query: 367 GILGAFSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWS 426 I+G + ++ V+ S AV G I WLD+LY SY+KL+ TL+KY PQAYMN+KRKST G+S Sbjct: 245 VIIGTYLVIIAVSASQAVFGAIHWLDFLYILSYIKLSTTLVKYFPQAYMNFKRKSTEGFS 304 Query: 427 IGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDIFFILQHYVFYR 486 I N LD GG L ILQMV+NA+N++DW S GD KFGLG+FS++FD+ FI+QHY+ YR Sbjct: 305 ILNRLLDIAGGLLGILQMVINAWNFDDWQSILGDPVKFGLGVFSILFDLVFIVQHYILYR 364 >UniRef50_O60931 Cluster: Cystinosin; n=27; Eumetazoa|Rep: Cystinosin - Homo sapiens (Human) Length = 367 Score = 302 bits (741), Expect = 2e-80 Identities = 136/246 (55%), Positives = 176/246 (71%) Query: 241 LRITVMHSNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTM 300 +R V+ S+ I+II+ ++GWIYF AWS+SFYPQ+ +N++RKSV+GL+FDF+ALN+ GF Sbjct: 113 IRFLVIRSSAISIINQVIGWIYFVAWSISFYPQVIMNWRRKSVIGLSFDFVALNLTGFVA 172 Query: 301 YSLFNCGLYFSKEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQR 360 YS+FN GL + I+ ++ ++P G+NPV NDVFFSLHA TLI I QC LYER QR Sbjct: 173 YSVFNIGLLWVPYIKEQFLLKYPNGVNPVNSNDVFFSLHAVVLTLIIIVQCCLYERGGQR 232 Query: 361 VSTVGRGILGAFSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRK 420 VS G L VT +A VG I WL +L+ SY+KLA+TL+KY PQAYMN+ K Sbjct: 233 VSWPAIGFLVLAWLFAFVTMIVAAVGVITWLQFLFCFSYIKLAVTLVKYFPQAYMNFYYK 292 Query: 421 STVGWSIGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDIFFILQ 480 ST GWSIGN+ LDF GG S+LQM L +YN + W FGD TKFGLG+FS+VFD+ F +Q Sbjct: 293 STEGWSIGNVLLDFTGGSFSLLQMFLQSYNNDQWTLIFGDPTKFGLGVFSIVFDVVFFIQ 352 Query: 481 HYVFYR 486 H+ YR Sbjct: 353 HFCLYR 358 >UniRef50_Q09500 Cluster: Cystinosin homolog; n=3; Caenorhabditis|Rep: Cystinosin homolog - Caenorhabditis elegans Length = 404 Score = 294 bits (722), Expect = 4e-78 Identities = 134/260 (51%), Positives = 182/260 (70%) Query: 234 VNLDTVYLRITVMHSNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLAL 293 ++L+ + RITV+ S+ + I+ I+GW YF AWS+SFYPQ+Y+NFKRKSVVGLNFDFL+L Sbjct: 108 LDLEDAFARITVIRSHFLAILIQIVGWTYFFAWSISFYPQMYLNFKRKSVVGLNFDFLSL 167 Query: 294 NIMGFTMYSLFNCGLYFSKEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFL 353 N++GF Y++FN +Y++ ++NEY +PR PV LNDV F++HA A ITI QC Sbjct: 168 NLVGFCAYAIFNLLMYYNSHVKNEYNIVNPRSPPPVLLNDVVFAVHAFLACFITILQCLF 227 Query: 354 YEREEQRVSTVGRGILGAFSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQA 413 YER+ Q VS+ ++ + + + V+ KI+ L ++ SY+K+A+T KY PQA Sbjct: 228 YERDNQSVSSKCIALMIVLISFGFCSAAATVLRKIQLLSFVTSLSYIKMAVTCCKYFPQA 287 Query: 414 YMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVF 473 Y NY RKSTVGWSIGNI LDF GG L ILQM+L A N NDW +F+ + KFGLG S+ F Sbjct: 288 YFNYTRKSTVGWSIGNIMLDFTGGTLDILQMILQAVNVNDWSAFYANPVKFGLGFVSIFF 347 Query: 474 DIFFILQHYVFYRNADKKYN 493 DI F++QHYV Y NA+ +N Sbjct: 348 DIIFMVQHYVLYPNAEVPHN 367 >UniRef50_UPI0000E4776A Cluster: PREDICTED: similar to cystinosin, partial; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to cystinosin, partial - Strongylocentrotus purpuratus Length = 324 Score = 269 bits (659), Expect = 2e-70 Identities = 123/264 (46%), Positives = 177/264 (67%), Gaps = 9/264 (3%) Query: 190 VPPSIEIPGSNEPNKTVVISYDICAYGKSPGHSEVTFNVTPPGFVNLDTVYLRITVMHSN 249 +P ++IP ++ ++ +S S G ++ N T +L +++ + V+ S+ Sbjct: 66 IPSEVDIPSNSSSPVSITVS------SLSVGVCHISMNTTSSELGDLSGLFVEVNVVQSS 119 Query: 250 EINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLY 309 ++I+ ++GWIYF AWSVSFYPQ+ +N KRKSV+GLNFDFLA NI GF Y +FN G+Y Sbjct: 120 ALSIVVIVVGWIYFLAWSVSFYPQVILNIKRKSVIGLNFDFLAYNITGFVAYGVFNVGMY 179 Query: 310 FSKEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQRVSTVGRGIL 369 + + I++ Y +++P G+NPV LNDV F+LHA T ITI QCF+YER QRVS + R IL Sbjct: 180 WIEPIKDAYKAKNPYGVNPVLLNDVIFTLHAVLITAITIFQCFIYERGRQRVSIISRVIL 239 Query: 370 GA---FSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWS 426 F+ + ++ + + I WL+++YY SY+KL +TLIKY+PQ YMNY+RKST GWS Sbjct: 240 AGMWLFALITLIITAASSGSVITWLEFIYYFSYIKLGVTLIKYIPQVYMNYRRKSTEGWS 299 Query: 427 IGNIFLDFVGGFLSILQMVLNAYN 450 IGN+ LD GG S+LQM L +YN Sbjct: 300 IGNVLLDSTGGSFSLLQMFLISYN 323 >UniRef50_Q54WT7 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 284 Score = 267 bits (654), Expect = 6e-70 Identities = 122/241 (50%), Positives = 164/241 (68%), Gaps = 1/241 (0%) Query: 251 INIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLYF 310 ++IIS I+GWIYFA WS+SFYPQ+ +NF++K+V+GL+FDFL NI G+ YS+FN LYF Sbjct: 4 LSIISIIIGWIYFACWSLSFYPQVILNFRKKNVIGLSFDFLLFNITGYACYSVFNSVLYF 63 Query: 311 SKEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQRVSTVGRGILG 370 K ++NEY+ ++ + PVQ +D+ F++H T ITI QCF+Y+R Q+ S +G GI Sbjct: 64 DKLVKNEYYDKYGPPI-PVQQSDIAFAIHGFVLTAITIIQCFIYDRGNQKNSKLGIGIAT 122 Query: 371 AFSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNI 430 +IV + WL + Y SYVKL IT IKY+PQAY+N+K KST GWS+ N+ Sbjct: 123 LIWVSLIVMTILGFSNVFTWLWVINYYSYVKLFITFIKYIPQAYLNFKNKSTSGWSVHNV 182 Query: 431 FLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDIFFILQHYVFYRNADK 490 LDF GG LS+LQM L+ + +W F GD K GL LFS+ FDI FI+QHY+ YRN Sbjct: 183 LLDFSGGVLSLLQMFLDVADSGNWNIFTGDPVKLGLSLFSIAFDILFIIQHYILYRNPKS 242 Query: 491 K 491 K Sbjct: 243 K 243 >UniRef50_P57758 Cluster: Cystinosin homolog; n=9; Magnoliophyta|Rep: Cystinosin homolog - Arabidopsis thaliana (Mouse-ear cress) Length = 270 Score = 228 bits (558), Expect = 3e-58 Identities = 111/234 (47%), Positives = 154/234 (65%), Gaps = 3/234 (1%) Query: 254 ISY-IMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLYFSK 312 ISY I+GWI FA+WS+SFYPQ+ +NF+R+SVVGLNFDF+ LN+ + Y ++N LYFS Sbjct: 11 ISYEIVGWIAFASWSISFYPQLILNFRRRSVVGLNFDFVMLNLTKHSSYMIYNVCLYFSP 70 Query: 313 EIQNEYFSRH-PRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQRVSTVGRGILGA 371 IQ +YF + + + PV NDV FS+HA T +T+ Q F+YER Q+VS + GI+ Sbjct: 71 VIQKQYFDTYGDKEMIPVAANDVAFSIHAVVMTAVTLFQIFIYERGPQKVSRLAIGIVVV 130 Query: 372 FSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNIF 431 + IA+ WL + + +++ +T +KY+PQA MN+ RKSTVGWSIGNI Sbjct: 131 VWGFAAICFFIALPTH-SWLWLISIFNSIQVFMTCVKYIPQAKMNFTRKSTVGWSIGNIL 189 Query: 432 LDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDIFFILQHYVFY 485 LDF GG + LQMV+ + + N W +F+G+ K L L S+ FDI F+ QHYV Y Sbjct: 190 LDFTGGLANYLQMVIQSIDQNSWKNFYGNMGKTLLSLISIFFDILFMFQHYVLY 243 >UniRef50_Q4DCC2 Cluster: Cystinosin, putative; n=2; Trypanosoma cruzi|Rep: Cystinosin, putative - Trypanosoma cruzi Length = 383 Score = 220 bits (537), Expect = 9e-56 Identities = 104/248 (41%), Positives = 153/248 (61%), Gaps = 5/248 (2%) Query: 252 NIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLYFS 311 N IS ++GWIYF AW VSF PQ+Y N +R+SVVG +F+F+ LNI GF YS++ Y + Sbjct: 110 NRISALIGWIYFLAWGVSFLPQLYFNMRRRSVVGQSFEFVYLNIFGFLCYSVYTLCFYAN 169 Query: 312 KEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQRVSTVGRGILGA 371 + N Y RH N V LNDV F+++A L+ Q ++R Q++S + G++ Sbjct: 170 NNVNNMYKDRHNGSSNNVALNDVVFAVYALACCLLNGLQIIFFDRGGQKMSILATGLIVL 229 Query: 372 FSAVVI-----VTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWS 426 V++ + G + +LD LY S VKL I+++KYVPQ Y+NYKRK T+GW+ Sbjct: 230 IFFVIVLWTCLIAGGVKRDVFFNYLDLLYGLSLVKLGISIVKYVPQVYLNYKRKCTIGWN 289 Query: 427 IGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDIFFILQHYVFYR 486 I NI LDF GG LSILQ V++++ +DW G+ KF LG S+++D+ F +QH++ Y Sbjct: 290 IWNILLDFTGGILSILQEVIDSWVTSDWDGMTGNPVKFALGSVSILYDLVFFVQHFLLYN 349 Query: 487 NADKKYNL 494 +K+ L Sbjct: 350 ENNKRLAL 357 >UniRef50_A2Q8N4 Cluster: Function: human CTNS is a lysosomal cystine transporter. precursor; n=9; Pezizomycotina|Rep: Function: human CTNS is a lysosomal cystine transporter. precursor - Aspergillus niger Length = 288 Score = 204 bits (497), Expect = 6e-51 Identities = 104/253 (41%), Positives = 154/253 (60%), Gaps = 15/253 (5%) Query: 251 INIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLYF 310 + +S ++GWIY WS SFYPQ NF+R+S GL DF +N++GF Y+++ + Sbjct: 9 VRALSRLLGWIYTFCWSASFYPQPINNFRRRSTTGLAIDFPTINVLGFVCYTIYTSAFLY 68 Query: 311 SKEIQNEYFSRHPRGLNP-VQLNDVFFSLHAAFATLITITQC--FLYEREEQRVSTVGRG 367 S I+++Y +RHP +P V+ ND F+LHA + IT TQ F++ + R V + Sbjct: 69 SPVIRHQYAARHPLAEDPTVRFNDFAFALHAVVLSFITYTQFWPFIWGFKVSRHQKVSKP 128 Query: 368 ILGAF-SAVVIVTGSIAVV-GKIE----------WLDWLYYCSYVKLAITLIKYVPQAYM 415 + G F ++V VT I +V G+ W+D +Y SYVKL IT++KYVPQA++ Sbjct: 129 VAGLFWGSIVGVTIVIFIVLGQSPNNGYDPYSWAWIDVIYALSYVKLVITIVKYVPQAWV 188 Query: 416 NYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDI 475 NYKRKST GWSIG I D GG LS+ Q++L++ +DW G+ KF L ++ FD+ Sbjct: 189 NYKRKSTYGWSIGQILFDLSGGVLSLAQLLLDSSFQDDWSGVTGNPIKFLLSNVTIFFDL 248 Query: 476 FFILQHYVFYRNA 488 F++QHY+ YR+A Sbjct: 249 IFVVQHYILYRDA 261 >UniRef50_UPI0000DA2024 Cluster: PREDICTED: similar to Cystinosin; n=1; Rattus norvegicus|Rep: PREDICTED: similar to Cystinosin - Rattus norvegicus Length = 350 Score = 201 bits (491), Expect = 3e-50 Identities = 94/173 (54%), Positives = 121/173 (69%) Query: 241 LRITVMHSNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTM 300 ++ V+HS +++I+ ++GWIYF AWSVSFYPQ+ N++RKSVVGL+FDFLALN+ GF Sbjct: 86 IQFLVIHSRIVSVINQVIGWIYFMAWSVSFYPQVIQNWRRKSVVGLSFDFLALNLTGFVA 145 Query: 301 YSLFNCGLYFSKEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQR 360 YS+FN GL + IQ E+ ++P G+NPV +ND FFSLHA TLI I QC LYER QR Sbjct: 146 YSVFNIGLLWVPYIQEEFLLKYPNGVNPVDINDAFFSLHAVALTLIVILQCCLYERGNQR 205 Query: 361 VSTVGRGILGAFSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQA 413 VS G L ++VT +A VG WL +L+ SY+KL ITLIKY PQA Sbjct: 206 VSRPSIGFLVLAWLFILVTMIVAAVGVTTWLQFLFCFSYIKLIITLIKYFPQA 258 >UniRef50_Q4SRV7 Cluster: Chromosome undetermined SCAF14488, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome undetermined SCAF14488, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 404 Score = 201 bits (490), Expect = 5e-50 Identities = 89/172 (51%), Positives = 121/172 (70%) Query: 241 LRITVMHSNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTM 300 + V+HS ++++S ++GWIYF WS+SFYPQ + N++RKSVVGLNFDFLALN+ GF Sbjct: 116 IHFMVIHSRGLDVLSQVLGWIYFLLWSLSFYPQAWENWRRKSVVGLNFDFLALNLTGFVA 175 Query: 301 YSLFNCGLYFSKEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQR 360 YS+FN L++ +Q E+ R+P+G+NPV NDVFFSLHA L+ + Q +Y+R Q+ Sbjct: 176 YSVFNVALFWVPAVQEEFLQRNPKGINPVSSNDVFFSLHAVLLCLVYLCQAAIYKRGGQK 235 Query: 361 VSTVGRGILGAFSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQ 412 VS +L +VT +A G I WLD+LYYCSY+KLA+TLIKYVPQ Sbjct: 236 VSWTAVSLLLVGWTFALVTLVLAGTGHITWLDFLYYCSYIKLAVTLIKYVPQ 287 Score = 109 bits (261), Expect = 3e-22 Identities = 45/75 (60%), Positives = 57/75 (76%) Query: 412 QAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSL 471 QA+MNY+R+ST GWS+G + +DF GG SILQM L +YN ++W FGD TKFGLG FS+ Sbjct: 321 QAFMNYRRQSTEGWSVGGVLMDFSGGLFSILQMFLQSYNNDEWRLVFGDPTKFGLGAFSV 380 Query: 472 VFDIFFILQHYVFYR 486 +FDI F+ QHY YR Sbjct: 381 LFDILFLTQHYCLYR 395 >UniRef50_Q7S781 Cluster: Related to CTNS protein [MIPS]; n=5; Pezizomycotina|Rep: Related to CTNS protein [MIPS] - Neurospora crassa Length = 298 Score = 196 bits (479), Expect = 1e-48 Identities = 107/264 (40%), Positives = 151/264 (57%), Gaps = 25/264 (9%) Query: 248 SNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALN-IMGFTMYSLFNC 306 S + +S++ GW YF WS+SFYPQ +NF RKS G DF +N + GF Y++ N Sbjct: 4 STFLTSLSHVFGWTYFTCWSLSFYPQSILNFSRKSTSGTTIDFPLINSLAGFFAYTISNI 63 Query: 307 GLYFSKEIQNEYFSRHPRGLNP-VQLNDVFFSLHAAFATLITITQCFLYEREEQRVSTVG 365 +S I+ +Y R+ +GL P VQLND+ F+ H +T++Q +L+ R ++G Sbjct: 64 AFAYSPLIRAQYAVRY-KGLTPTVQLNDITFAFHGLILCFVTVSQ-YLFPRAWGFAPSLG 121 Query: 366 ----RGILGAF-----SAVVIV------------TGSIAVVGKIEWLDWLYYCSYVKLAI 404 R ILG F A++I+ +G+ G WLD +Y SYVKL + Sbjct: 122 SRPSRFILGTFFGCVAGALIIIFRVWASPVRNDTSGAAVTEGGWVWLDAIYAVSYVKLVV 181 Query: 405 TLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKF 464 TLIKY PQ +NY+ +ST GWSI I LDF GG LSI Q +++Y DW G+ KF Sbjct: 182 TLIKYTPQVIVNYRNRSTEGWSILQILLDFGGGILSIAQQAIDSYQQGDWSGITGNPVKF 241 Query: 465 GLGLFSLVFDIFFILQHYVFYRNA 488 LG S+++D+ FI+QHYV YR+A Sbjct: 242 ALGNVSMIYDLVFIMQHYVLYRHA 265 >UniRef50_Q4P2H9 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 310 Score = 193 bits (471), Expect = 9e-48 Identities = 95/233 (40%), Positives = 137/233 (58%), Gaps = 1/233 (0%) Query: 254 ISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLYFSKE 313 +S ++GWIY AWS+SFYPQ+ N+ +S VGL+ DF+ LN +G T Y ++N LY + Sbjct: 27 LSQLLGWIYTLAWSLSFYPQVIHNYTHRSTVGLSTDFVFLNALGHTSYLVYNALLYLYEP 86 Query: 314 IQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQRVSTVGRGILGAFS 373 ++ Y H N VQ ND+ FSLHAA LIT+ Q +Y++ Q VS + L A Sbjct: 87 VRRAYRKTHSGRDNVVQFNDLIFSLHAALLALITLAQYLVYKKPNQHVSRSVQLSLAATL 146 Query: 374 AVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLD 433 VV++ + + WLD + S +KL +TL KY+PQ +N R+ST G++I N+ LD Sbjct: 147 TVVVLLAGARRLKLVSWLDIVACASTIKLGVTLTKYLPQIKLNRDRQSTDGFAIENVLLD 206 Query: 434 FVGGFLSILQMVLNA-YNYNDWVSFFGDATKFGLGLFSLVFDIFFILQHYVFY 485 GG LS+ Q++++A + + W GD K GL L S+ FDI QHY Y Sbjct: 207 LTGGVLSLAQLIIDAVWIQHSWSDVTGDWGKLGLALLSIAFDIILTWQHYALY 259 >UniRef50_A6R572 Cluster: Putative uncharacterized protein; n=1; Ajellomyces capsulatus NAm1|Rep: Putative uncharacterized protein - Ajellomyces capsulatus NAm1 Length = 306 Score = 190 bits (463), Expect = 9e-47 Identities = 99/236 (41%), Positives = 139/236 (58%), Gaps = 15/236 (6%) Query: 266 WSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLYFSKEIQNEYFSRHPRG 325 WS SFYPQ +N++R+S GL DF A N +GF Y ++ +S I+ +Y +RHP Sbjct: 18 WSASFYPQPILNYRRRSTHGLAIDFPATNTLGFICYMIYALAFLYSPLIREQYAARHPIS 77 Query: 326 LNP-VQLNDVFFSLHAAFATLITITQCF--LYEREEQRVSTVGRGILGAFSAVVIVTGSI 382 P V+ NDV F++HA + + ++Q + ++ + R + R I G F + V + Sbjct: 78 PEPTVRFNDVAFAIHAVVLSSLVLSQFWPSIWGFKVSRFQRISRPIAGVFWGCIFVVTLL 137 Query: 383 AVVGKIE------------WLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNI 430 AVV W+D Y SYVKL IT+IKY+PQA++NYKRKSTVGWSI I Sbjct: 138 AVVVAARGTGASLDPQDWAWIDVTYALSYVKLIITIIKYIPQAWVNYKRKSTVGWSISAI 197 Query: 431 FLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDIFFILQHYVFYR 486 LDF GG LS+LQ+++++ +DW G+ K LG S+ FDI FILQHY+ YR Sbjct: 198 LLDFTGGILSVLQLLIDSAFEDDWSGITGNPIKLLLGNVSVFFDIIFILQHYIIYR 253 Score = 34.7 bits (76), Expect = 6.6 Identities = 12/44 (27%), Positives = 25/44 (56%) Query: 254 ISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMG 297 ++Y + ++ + + PQ ++N+KRKS VG + + L+ G Sbjct: 160 VTYALSYVKLIITIIKYIPQAWVNYKRKSTVGWSISAILLDFTG 203 >UniRef50_A7SMR9 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 265 Score = 187 bits (455), Expect = 8e-46 Identities = 91/233 (39%), Positives = 136/233 (58%), Gaps = 1/233 (0%) Query: 253 IISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLYFSK 312 +++ I GW YF AW+VSFYPQIY N++RK VVGL+FD + ++ + Y ++N ++F Sbjct: 9 VLADIFGWGYFLAWTVSFYPQIYENWRRKCVVGLSFDMMTYFMISYIAYMIYNVVVFFDL 68 Query: 313 EIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQRVSTVGRGILGAF 372 IQ E +PV+L DV F++ T IT QC +YE Q++ + + F Sbjct: 69 NIQWEIIGNSNES-SPVKLTDVVFAILGLVCTGITCLQCVIYESGPQKIHFTTKVVFSVF 127 Query: 373 SAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFL 432 + + ++A WL L YC YVKLA++ Y+PQ ++NY+RK T G+ IG + L Sbjct: 128 VVALGICCALAGFKVTSWLFMLDYCGYVKLAVSFGSYLPQIWLNYRRKCTEGFHIGGVLL 187 Query: 433 DFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDIFFILQHYVFY 485 DF GG LS+LQM + + F G+ K LG+ +LVF+I +LQHY+ Y Sbjct: 188 DFSGGILSLLQMNIYCALEHSTKQFTGNIPKLVLGILTLVFNITLVLQHYMLY 240 >UniRef50_A1CUZ4 Cluster: L-cystine transporter, putative; n=4; Trichocomaceae|Rep: L-cystine transporter, putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 280 Score = 175 bits (427), Expect = 2e-42 Identities = 92/248 (37%), Positives = 141/248 (56%), Gaps = 13/248 (5%) Query: 251 INIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLYF 310 + +S +GW YF WSVSFYPQ+ N +R++ G + DF LN++G + Y++FN GL F Sbjct: 9 LQALSQGLGWSYFLLWSVSFYPQLIHNQRRRATSGFSLDFALLNVLGLSAYTVFNGGLLF 68 Query: 311 SKEIQNEYFSRHPRGLNP-VQLNDVFFSLHAAFATLITITQC-------FLYEREEQRVS 362 S I+ +Y RHP+ P V LND F++LH L+ +Q F +++ QR Sbjct: 69 SPVIRAQYAQRHPQSPEPPVHLNDFFYALHGTIICLLIYSQFQWPVLWKFESQKQTQRKP 128 Query: 363 TVGRGIL--GAFSAVVIVTGSIAVVGKI---EWLDWLYYCSYVKLAITLIKYVPQAYMNY 417 + +L G F V + + ++ +WLD LY +K+ +T IKY PQA+MNY Sbjct: 129 SRLTVVLLSGCFGLVAVEVMGLLCFPQLHSQQWLDVLYTIGNIKVFLTAIKYTPQAWMNY 188 Query: 418 KRKSTVGWSIGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDIFF 477 +ST G+ + I +DF GG LS++Q++++ DW G+ATK LG ++ FDI Sbjct: 189 CHQSTKGFCMIAILMDFTGGMLSLMQLIIDTSLQADWSGAQGNATKLVLGNLTIFFDIIL 248 Query: 478 ILQHYVFY 485 ++QHY Y Sbjct: 249 MVQHYCLY 256 >UniRef50_A0C517 Cluster: Chromosome undetermined scaffold_15, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_15, whole genome shotgun sequence - Paramecium tetraurelia Length = 274 Score = 171 bits (415), Expect = 6e-41 Identities = 101/246 (41%), Positives = 142/246 (57%), Gaps = 14/246 (5%) Query: 248 SNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCG 307 S +N IS I+GW YF WS SFY Q+Y NFK K+V G+ F+FL LN+ GF S ++ Sbjct: 16 SEVVNTISNIIGWTYFVCWSASFYGQLYENFKVKNVKGIAFEFLGLNLTGFLFLSAYSSA 75 Query: 308 LYFSKEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQC-FLYEREEQR-VST-- 363 Y+ FS + + D+FF+ HA TL+TI Q + Y++ + + VS Sbjct: 76 GYYKGGDNGWPFS------GDITVQDLFFAYHAVAITLLTIIQTGYYYKKGDNKGVSLWC 129 Query: 364 -VGRGILGAFSAVVIVTGSI---AVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKR 419 V +L + + ++ I V+ + E L+ LY+ Y KL I+ IKYVPQ ++NYKR Sbjct: 130 IVVLIVLWSQTIFYVLLTWIFDWQVIFQQEKLNVLYWMGYEKLFISFIKYVPQVFLNYKR 189 Query: 420 KSTVGWSIGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDIFFIL 479 KSTVGWSI NI LDF+GGFLS LQM+L++ N + KF L ++ FD F+ Sbjct: 190 KSTVGWSIFNILLDFMGGFLSFLQMLLDSLNGKSANLVDVNIVKFILSWIAMGFDGIFMF 249 Query: 480 QHYVFY 485 QHY+ Y Sbjct: 250 QHYILY 255 >UniRef50_UPI00006D0016 Cluster: PQ loop repeat family protein; n=1; Tetrahymena thermophila SB210|Rep: PQ loop repeat family protein - Tetrahymena thermophila SB210 Length = 267 Score = 157 bits (382), Expect = 6e-37 Identities = 91/250 (36%), Positives = 132/250 (52%), Gaps = 19/250 (7%) Query: 251 INIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLYF 310 + +++ I+GW YF+AWS+SFY Q+Y N+K++ G D+L N GF Y+++N Y+ Sbjct: 7 VEVLTQIIGWAYFSAWSISFYGQVYENYKQQRAEGCKIDYLIFNFSGFFFYTIYNVIGYW 66 Query: 311 SKEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQRVSTVGRGILG 370 N G V++ DV F++HA T + + Q F Y R + +++ Sbjct: 67 GDSEAN--------GTGDVEIQDVVFAIHALTLTCVALGQWFYYPRGKNQITPFCYAATC 118 Query: 371 AFSAVVIVTGSI--AVVGKI-EW---LDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVG 424 A + S+ V K W L + Y+KLAIT+ KY Q N KR+ST G Sbjct: 119 AMWIFALSYASLDKTVFNKDGSWPAKLSLASWLGYMKLAITIFKYTIQVIWNIKRQSTEG 178 Query: 425 WSIGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFG---DATKFGLGLFSLVFDIFFILQH 481 W+I NI D GG LS+LQ V+ A D + FG +A K+ LGL S+ FD+ FI+QH Sbjct: 179 WNIFNILCDITGGTLSVLQSVIQAIACGD--NPFGGALNAVKYLLGLISIFFDVIFIIQH 236 Query: 482 YVFYRNADKK 491 YV YR K Sbjct: 237 YVIYRGKKPK 246 >UniRef50_A0NH14 Cluster: ENSANGP00000023811; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000023811 - Anopheles gambiae str. PEST Length = 289 Score = 149 bits (362), Expect = 1e-34 Identities = 69/168 (41%), Positives = 107/168 (63%) Query: 239 VYLRITVMHSNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGF 298 +++++ V + I+S ++GW Y W++ Y Q + +++RKSVVGL+FDFL LNI+G Sbjct: 122 LFVQLKVAQYRPLIIVSMLIGWTYTVCWTIGDYFQAWTSYRRKSVVGLSFDFLYLNIVGN 181 Query: 299 TMYSLFNCGLYFSKEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREE 358 Y+ FN L+ S I++EYF RHP GLNPV NDV +++HA F L+ I QC++Y+ Sbjct: 182 CCYATFNVVLFCSAFIEDEYFRRHPFGLNPVVPNDVGYAVHAVFGNLVLIAQCYIYQNGG 241 Query: 359 QRVSTVGRGILGAFSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITL 406 VST + ++ + +V V A+ ++ WLD+LY SYVKL+ L Sbjct: 242 TVVSTAVKLLISGYVLMVSVFCGFAIEEQMHWLDFLYILSYVKLSTNL 289 >UniRef50_A0DZ98 Cluster: Chromosome undetermined scaffold_7, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_7, whole genome shotgun sequence - Paramecium tetraurelia Length = 252 Score = 145 bits (352), Expect = 2e-33 Identities = 85/239 (35%), Positives = 127/239 (53%), Gaps = 16/239 (6%) Query: 251 INIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLYF 310 + I+S I+GW YFAAWS+SFYPQIY N+K K+V GL+ D++ LNI G+ +++ Y Sbjct: 4 LQILSDIIGWTYFAAWSISFYPQIYENWKLKNVNGLSVDYVGLNITGYICLCIYSTAGYL 63 Query: 311 SKEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQRVSTVGRGILG 370 + + E + HP D+ F+ H T+I I Q Y + ++S +L Sbjct: 64 DQSL--EVGTIHP--------EDLAFAYHGLLCTIIIIGQMIFYPLGDNKLSIYIIAVLV 113 Query: 371 AFSAVV----IVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWS 426 + ++T + V + Y KL I+ IKY+PQ Y NYKRK T+GW+ Sbjct: 114 FLWTLTPIYFLLTQTFDVFHVSVSYNAYRMIGYDKLLISFIKYIPQVYWNYKRKKTLGWN 173 Query: 427 IGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDIFFILQHYVFY 485 I LD GG LS+LQ +++ + + V+ + KF LGL ++ FD I QHY Y Sbjct: 174 IWVSLLDITGGLLSVLQTIMDQFIQD--VNNEINPVKFALGLLTIGFDSILIFQHYFLY 230 >UniRef50_A6SSL3 Cluster: H+ driven lysosomal cystine transporter; n=2; Pezizomycotina|Rep: H+ driven lysosomal cystine transporter - Botryotinia fuckeliana B05.10 Length = 184 Score = 121 bits (292), Expect = 4e-26 Identities = 58/121 (47%), Positives = 77/121 (63%), Gaps = 2/121 (1%) Query: 368 ILGAFSAVVIVTG--SIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGW 425 I+G ++VVIV VV W+D +Y SYVKL IT +KY+PQ NY+ +ST GW Sbjct: 40 IVGVATSVVIVLARQDEDVVRGWAWIDVVYVISYVKLVITTVKYMPQVLTNYRNRSTTGW 99 Query: 426 SIGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDIFFILQHYVFY 485 SIG I LDF GG LSILQ+ +++Y DW G+ K LG S+ FD+ FI+QHY+ Y Sbjct: 100 SIGGILLDFAGGVLSILQLGIDSYLQGDWSGVTGNPVKLMLGNVSIFFDVIFIVQHYILY 159 Query: 486 R 486 + Sbjct: 160 K 160 >UniRef50_Q5KPP2 Cluster: L-cystine transporter, putative; n=2; Filobasidiella neoformans|Rep: L-cystine transporter, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 284 Score = 118 bits (285), Expect = 3e-25 Identities = 83/263 (31%), Positives = 127/263 (48%), Gaps = 33/263 (12%) Query: 257 IMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLYFS----K 312 + G YF AWS SFY Q+ NFKRK+ GL+ DF+ +N +GF +L+N G YFS K Sbjct: 13 LTGVTYFIAWSYSFYIQLVHNFKRKTTHGLSPDFVWVNPLGFLALTLWNWGAYFSPVARK 72 Query: 313 EIQNEY-------------FSRHPRGLNPVQLNDVFFS---------------LHAAFAT 344 + Q+ + FS H ++ + L VF S +H + A Sbjct: 73 QYQDRHHGHLPQVSTSDLAFSLHALIISTITLAQVFCSSDQHSDEASPLISDSVHNSAAG 132 Query: 345 LITITQCFLYEREEQRVSTVGRGILGAFSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAI 404 + + + R S V + LG V GK ++LDWLYY +K+ I Sbjct: 133 DDSESSNLVIFHSPIRPSPVAQLFLGGIVISPFVYAIFVWTGKAQFLDWLYYVGNIKVVI 192 Query: 405 TLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNA-YNYNDWVSFFGDATK 463 + +KY+PQ +N++ ++ G++IG I D +G LS Q+V+++ + +D + K Sbjct: 193 SAVKYIPQVVLNHRMRAVNGFAIGVIICDIIGSVLSFSQLVISSVFIDHDPSGIIANPAK 252 Query: 464 FGLGLFSLVFDIFFILQHYVFYR 486 GL S FD+ FI Q Y YR Sbjct: 253 LGLAGLSFTFDLVFIAQKYWLYR 275 >UniRef50_Q5C2M8 Cluster: SJCHGC09199 protein; n=1; Schistosoma japonicum|Rep: SJCHGC09199 protein - Schistosoma japonicum (Blood fluke) Length = 110 Score = 111 bits (267), Expect = 5e-23 Identities = 53/96 (55%), Positives = 64/96 (66%) Query: 407 IKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGL 466 IKY PQA MN++RKSTVGWSIGNI LDF GG LSI QMV+ AYN ND S G K GL Sbjct: 2 IKYTPQALMNFRRKSTVGWSIGNIILDFSGGILSIAQMVIIAYNNNDVSSITGSPIKLGL 61 Query: 467 GLFSLVFDIFFILQHYVFYRNADKKYNLDVKSLIHS 502 G+ S+ FDI F++QH+ Y ++ N +L S Sbjct: 62 GILSIGFDILFMVQHWCLYPSSSSSSNSSSNALTSS 97 >UniRef50_P17261 Cluster: Cystine transporter; n=4; Saccharomycetales|Rep: Cystine transporter - Saccharomyces cerevisiae (Baker's yeast) Length = 260 Score = 96.3 bits (229), Expect = 2e-18 Identities = 69/246 (28%), Positives = 123/246 (50%), Gaps = 23/246 (9%) Query: 257 IMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFT--MYSLFNCGLYFSKEI 314 I+G +Y +WS+S YP I N++ KS ++ DF+ LN G++ + S+F LY K Sbjct: 7 ILGIVYVTSWSISMYPPIITNWRHKSASAISMDFVMLNTAGYSYLVISIF-LQLYCWKMT 65 Query: 315 QNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQRVSTVGRGILGAFSA 374 +E P+ + D ++ LH ++ +TQ R + R + + Sbjct: 66 GDESDLGRPK----LTQFDFWYCLHGCLMNVVLLTQVVAGARIWRFPGKGHRKMNPWYLR 121 Query: 375 VVIVTGSIAVVGKIE------WLDW-----LYYCS---YVKLAITLIKYVPQAYMNYKRK 420 +++ + +I + ++ W DW L YC+ +K++++LIKY+PQ N RK Sbjct: 122 ILLASLAIFSLLTVQFMYSNYWYDWHNSRTLAYCNNLFLLKISMSLIKYIPQVTHNSTRK 181 Query: 421 STVGWSIGNIFLDFVGGFLSILQMVLNAYNYNDWV--SFFGDATKFGLGLFSLVFDIFFI 478 S + I +FLD GG S+LQ++ N + +F + K GL + +L+F+ FI Sbjct: 182 SMDCFPIQGVFLDVTGGIASLLQLIWQLSNDQGFSLDTFVTNFGKVGLSMVTLIFNFIFI 241 Query: 479 LQHYVF 484 +Q +V+ Sbjct: 242 MQWFVY 247 >UniRef50_Q756J2 Cluster: AER269Cp; n=1; Eremothecium gossypii|Rep: AER269Cp - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 247 Score = 94.3 bits (224), Expect = 8e-18 Identities = 71/249 (28%), Positives = 129/249 (51%), Gaps = 26/249 (10%) Query: 257 IMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLYFSKEI-Q 315 ++G++Y W+VS YP ++IN+KR+S L+ ++ N +G+T L L + Q Sbjct: 6 LLGYLYATCWAVSMYPPLWINWKRQSARALSKGYVVFNCIGYTALVL---SLVVQTVLWQ 62 Query: 316 NEYFSRHPRGLNP-VQLNDVFFSLHAAFATLITITQCFLYER-------EEQRVSTVGRG 367 NE + P V +D ++++H+ + +Q R R+ST R Sbjct: 63 NE--GDTSSAVRPSVGWSDYWYAMHSWLLNGLLASQVLWGTRLWGFTGEPANRMSTAHRK 120 Query: 368 ILGAFSAVVIVTGSIAVVGKIEWL-----DWLYYCS---YVKLAITLIKYVPQAYMNYKR 419 ++ F + + G++ V I L+YC ++K+ ++++KY+ QA NY+R Sbjct: 121 MMQLFIGLFCI-GTVQYVVSITQTGLNNQSTLFYCHVLYFIKIIMSVLKYIAQAKHNYER 179 Query: 420 KSTVGWSIGNIFLDFVGGFLSILQMVLNAYNYN--DWVSFFGDATKFGLGLFSLVFDIFF 477 KSTVG+S+ ++ LD GG S+ Q+VL+ + + ++ K G+GL SL+F+ + Sbjct: 180 KSTVGFSMLSVSLDICGGVFSLAQLVLDLTEKSGISVTTVKANSGKLGIGLVSLLFNFVY 239 Query: 478 ILQHYVFYR 486 I Q ++ YR Sbjct: 240 ISQ-WLLYR 247 >UniRef50_Q6CID8 Cluster: Kluyveromyces lactis strain NRRL Y-1140 chromosome F of strain NRRL Y- 1140 of Kluyveromyces lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces lactis strain NRRL Y-1140 chromosome F of strain NRRL Y- 1140 of Kluyveromyces lactis - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 250 Score = 83.0 bits (196), Expect = 2e-14 Identities = 65/250 (26%), Positives = 120/250 (48%), Gaps = 29/250 (11%) Query: 257 IMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFT--MYSLFNCGLYFSKEI 314 ++G Y WSVS YP ++ N+K + ++FD++ LN +G++ + S+ L++++ Sbjct: 4 VLGITYVICWSVSVYPVVWANWKNGNANAVSFDYVVLNTVGYSCLLASMVLQKLFWAEGT 63 Query: 315 QNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYER---------EEQRVSTVG 365 + G +D+ + H + ++Q L R ++ TV Sbjct: 64 DETLIAPEISG------SDLIYCGHGTLLCFVLLSQFLLGNRLWNFSHTTRTHPKMHTVY 117 Query: 366 RGILGAFSAVVIVTG-----SIAVVGKIEWLDWLYYC---SYVKLAITLIKYVPQAYMNY 417 + + VV+V I VG + L YC S VK+ ++LIK++PQ N+ Sbjct: 118 KRMFSIIMLVVLVITIIFFTDILTVG-LSNATLLSYCNNLSLVKITMSLIKHLPQVRHNF 176 Query: 418 KRKSTVGWSIGNIFLDFVGGFLSILQMVLNAYNYND---WVSFFGDATKFGLGLFSLVFD 474 +RKS G+ I + +D +G S+ Q+ L + +SFF + K G+GL +L+F+ Sbjct: 177 QRKSMAGFPIQSTCIDVLGSVCSLSQLALRLASKPQGLTLMSFFTNFGKIGIGLITLLFN 236 Query: 475 IFFILQHYVF 484 I ++ Q V+ Sbjct: 237 IVYVSQWIVY 246 >UniRef50_Q54JY3 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 187 Score = 56.0 bits (129), Expect = 3e-06 Identities = 48/206 (23%), Positives = 98/206 (47%), Gaps = 29/206 (14%) Query: 248 SNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCG 307 S ++ ++ YI+G + + + + PQ+Y+NFKRKSV G + + + ++G + Sbjct: 8 SYKLELLYYILGILSSILFGIQYLPQMYLNFKRKSVQGFSSSGIIIKLVGASF------- 60 Query: 308 LYFSKEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQRVSTVGRG 367 L+ + + E P+ VF+ L F I + Q +Y+ + +T Sbjct: 61 LFVNSWLTGESM--------PI----VFYGLINVFQHTIFMFQFSIYDTIKG--ATKYLP 106 Query: 368 ILGAFSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWSI 427 +G F + + G +++ + ++ + K L+ ++PQ + Y+ KST G S+ Sbjct: 107 WIG-FPIIPFLIG-------LQYPNTMFITNSFKPITQLLSHLPQVILCYQSKSTTGVSL 158 Query: 428 GNIFLDFVGGFLSILQMVLNAYNYND 453 + +L+F+GG +L M + N N+ Sbjct: 159 PSQYLNFIGGIAGVLSMYIKNNNNNN 184 Score = 43.2 bits (97), Expect = 0.019 Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 3/87 (3%) Query: 391 LDWLYYCSYVKLAITL-IKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNAY 449 L+ LYY + +I I+Y+PQ Y+N+KRKS G+S I + VG + L Sbjct: 11 LELLYYILGILSSILFGIQYLPQMYLNFKRKSVQGFSSSGIIIKLVGASFLFVNSWLTGE 70 Query: 450 NYNDWVSFFGDATKFGLGLFSLVFDIF 476 + + F+G F +F F I+ Sbjct: 71 SMP--IVFYGLINVFQHTIFMFQFSIY 95 >UniRef50_Q6C2U6 Cluster: Similar to tr|Q12010 Saccharomyces cerevisiae YOL092w; n=1; Yarrowia lipolytica|Rep: Similar to tr|Q12010 Saccharomyces cerevisiae YOL092w - Yarrowia lipolytica (Candida lipolytica) Length = 278 Score = 50.8 bits (116), Expect = 9e-05 Identities = 25/63 (39%), Positives = 38/63 (60%), Gaps = 1/63 (1%) Query: 236 LDTVYLRITV-MHSNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALN 294 +D VY + +H + + +S IMG I A W + F PQIY NFKR+S GL+ F+ + Sbjct: 1 MDAVYTAVQPPIHGLDSSALSGIMGCISIACWIIVFTPQIYENFKRQSSEGLSLSFVVIW 60 Query: 295 IMG 297 ++G Sbjct: 61 LIG 63 Score = 39.5 bits (88), Expect = 0.23 Identities = 17/48 (35%), Positives = 28/48 (58%) Query: 250 EINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMG 297 E+N++ GW+ A + S PQI +N++RKS G++F F +G Sbjct: 184 EMNMLGQFFGWLCAAFYLGSRVPQIVLNYERKSCEGISFMFFLFACLG 231 Score = 35.9 bits (79), Expect = 2.9 Identities = 14/47 (29%), Positives = 28/47 (59%) Query: 400 VKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVL 446 + +A +I + PQ Y N+KR+S+ G S+ + + +G ++L +L Sbjct: 27 ISIACWIIVFTPQIYENFKRQSSEGLSLSFVVIWLIGDIFNVLGAIL 73 >UniRef50_Q5AFJ5 Cluster: Putative uncharacterized protein; n=1; Candida albicans|Rep: Putative uncharacterized protein - Candida albicans (Yeast) Length = 240 Score = 49.6 bits (113), Expect = 2e-04 Identities = 46/196 (23%), Positives = 86/196 (43%), Gaps = 17/196 (8%) Query: 273 QIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLYFSKEIQNEYFSRHPRGLN-PVQL 331 Q+ N ++K++ G++FD+ +++ S+ + LY NEY R+P N P+ L Sbjct: 20 QLQYNKQKKTIYGISFDYTLFSVLS-QFLSILSSFLYIHT---NEYSIRYPIYPNLPISL 75 Query: 332 NDVFFSLHAAFATLITITQCFLY---EREEQRVSTVGRGILGAFSAVVIVTGSIAVV--G 386 V F + F ++ + Q +Y Q +S LG+ + + + + G Sbjct: 76 PLVVFQVLQCFFLILVLLQLRIYINTRNTNQGISPYSLIFLGSLALFLSWISKLYIYRQG 135 Query: 387 KIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVG----WS---IGNIFLDFVGGFL 439 KI LD + + Y I+ +K++P MN+ + +G WS I + L +G + Sbjct: 136 KIISLDLIDWIWYAGRIISCVKFMPIISMNWFDQCVIGMFPYWSHFQISVLLLQLLGKYS 195 Query: 440 SILQMVLNAYNYNDWV 455 + NY W+ Sbjct: 196 YFFKWWQIPVNYPTWL 211 >UniRef50_A3LX51 Cluster: Mannosyltransferase; n=5; Saccharomycetales|Rep: Mannosyltransferase - Pichia stipitis (Yeast) Length = 292 Score = 48.8 bits (111), Expect = 4e-04 Identities = 59/222 (26%), Positives = 101/222 (45%), Gaps = 16/222 (7%) Query: 268 VSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLYFSKEIQNEYFSRHPRGLN 327 +S+ PQ + + +++ GL+ +FL L ++++L N L SK ++ + N Sbjct: 38 ISYLPQYHRIYSKRTSEGLSTNFLLLGSCS-SIFTLTNIILVSSKA-RHCCATGALNTFN 95 Query: 328 PV--QLNDVFFSLHAAFATLITI-----TQCFLYE--REEQRVSTVGR--GILGAFSAVV 376 + QLN V L A LI + TQ L + E QR+ VG+ + G S V Sbjct: 96 CINSQLNLVQIGLQCTCAILILVFVLILTQNSLKQDKHEYQRIVQVGKLVALHGVVSIVQ 155 Query: 377 IVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVG 436 IV G + + + + + +T+IKYVPQ Y Y K SIG + + G Sbjct: 156 IVVGLYSDKSVLYSIASIN--GLLSTLLTVIKYVPQIYTTYTLKHPGTLSIGMMCIQTPG 213 Query: 437 GFLSILQMVL-NAYNYNDWVSFFGDATKFGLGLFSLVFDIFF 477 GF+ + +++ WVS+ A+ G+ L ++ +F Sbjct: 214 GFVFTATLFFTKGSHWSSWVSYLVAASLQGVLLAMCLYYEYF 255 >UniRef50_Q54F66 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 449 Score = 47.6 bits (108), Expect = 9e-04 Identities = 54/212 (25%), Positives = 94/212 (44%), Gaps = 26/212 (12%) Query: 250 EINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLY 309 E I+S + G + WSV PQI++N+KRKS G++ + CG+ Sbjct: 2 ENKILSNLFGIVGTILWSVQLVPQIHLNYKRKSTKGVSPTCFG---------CWYACGVI 52 Query: 310 FSKEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYERE---EQRVSTVGR 366 N F+R P L VQ++ FSL +L+ + Q Y+++ ++ + T+G Sbjct: 53 LG---TNLVFNREPPAL-VVQIS--CFSLF----SLVIVMQHLFYQKKYNLKRLLFTIGL 102 Query: 367 GILGAFSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWS 426 +L A +I SI + + + + PQ Y+ K VG S Sbjct: 103 CVLVTI-ATIISLYSILNAKHTNSFVLQLILTIAATGLMAVGFFPQILEVYQEK--VGLS 159 Query: 427 IGNIFLDFVGGFLSILQMVLNA-YNYNDWVSF 457 + + +DF GG SIL +V + ++Y + ++ Sbjct: 160 MIFVVMDFFGGVFSILSLVFHVPFDYMSFSTY 191 >UniRef50_Q6FL26 Cluster: Candida glabrata strain CBS138 chromosome L complete sequence; n=1; Candida glabrata|Rep: Candida glabrata strain CBS138 chromosome L complete sequence - Candida glabrata (Yeast) (Torulopsis glabrata) Length = 329 Score = 44.0 bits (99), Expect = 0.011 Identities = 22/44 (50%), Positives = 28/44 (63%) Query: 254 ISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMG 297 +S I G I A W V F PQIY NF+RKS GL+ F+ L ++G Sbjct: 13 VSEIAGSISIACWVVVFAPQIYENFRRKSSDGLSLMFIILWLIG 56 Score = 37.9 bits (84), Expect = 0.71 Identities = 21/66 (31%), Positives = 35/66 (53%) Query: 248 SNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCG 307 S ++NI++ I G++ + S PQI +NFKRKS G++ F +G + L Sbjct: 229 SEKMNILAQIFGYLSAVLYLGSRIPQILLNFKRKSCEGVSLLFFLFACLGNINFILSVLA 288 Query: 308 LYFSKE 313 + SK+ Sbjct: 289 VSVSKK 294 >UniRef50_A7THU6 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 283 Score = 44.0 bits (99), Expect = 0.011 Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 3/92 (3%) Query: 410 VPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNA--YNYNDWVSFFGDATKFGLG 467 +PQ NYKRKST G S ++ F + +V + + ND F + F +G Sbjct: 170 LPQLLKNYKRKSTDGISPSLFWMTFTSNVTYNISIVTSEKFLSSNDKRGFILNELPFIIG 229 Query: 468 LF-SLVFDIFFILQHYVFYRNADKKYNLDVKS 498 +++FDI + QHY+ YR ++ + S Sbjct: 230 NSGTIIFDIVYFYQHYILYRETQQQQQQRINS 261 >UniRef50_A5DZI3 Cluster: Putative uncharacterized protein; n=1; Lodderomyces elongisporus NRRL YB-4239|Rep: Putative uncharacterized protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 392 Score = 42.7 bits (96), Expect = 0.025 Identities = 22/44 (50%), Positives = 26/44 (59%) Query: 254 ISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMG 297 IS I G I A W + F PQIY NF RKS GL+ F+ L + G Sbjct: 16 ISGITGSISLACWIIVFAPQIYENFTRKSSEGLSLTFIILWLAG 59 Score = 36.3 bits (80), Expect = 2.2 Identities = 16/48 (33%), Positives = 26/48 (54%) Query: 254 ISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMY 301 ++ GW+ + VS PQI +N++RKS G++F F +G Y Sbjct: 248 LAQTFGWLCAILYLVSRVPQIVLNYERKSCEGISFMFFLFACLGNLTY 295 Score = 35.5 bits (78), Expect = 3.8 Identities = 18/47 (38%), Positives = 26/47 (55%) Query: 400 VKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVL 446 + LA +I + PQ Y N+ RKS+ G S+ I L G ++L VL Sbjct: 23 ISLACWIIVFAPQIYENFTRKSSEGLSLTFIILWLAGDVFNVLGAVL 69 >UniRef50_A3M0K0 Cluster: Predicted protein; n=1; Pichia stipitis|Rep: Predicted protein - Pichia stipitis (Yeast) Length = 249 Score = 42.7 bits (96), Expect = 0.025 Identities = 41/161 (25%), Positives = 71/161 (44%), Gaps = 11/161 (6%) Query: 273 QIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLYFSKEIQNEYFSRHPRGLNP-VQL 331 QI N +KS+ GL++D+LAL M + + +K ++ +Y R P + P V + Sbjct: 22 QIKHNKIKKSIYGLSYDYLALTWTSDLMAVMSSINYNNNKHVKRQYGRRFP--IYPDVPV 79 Query: 332 NDVFFSLH--AAFATLITITQCF-LYERE---EQRVSTVGRGILGAF--SAVVIVTGSIA 383 + V SL + + + Q F +Y R Q +S + LGA + ++ Sbjct: 80 DSVLVSLEMISFLVSTALLFQTFCIYHRTRNVNQCISGLNMFFLGALIVGLIYVIKAYSY 139 Query: 384 VVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVG 424 + LD + Y + ++KY+PQ MN+ VG Sbjct: 140 HESTVVLLDVIDYMWLISRTTAIVKYMPQLVMNWFGSCVVG 180 >UniRef50_Q7RZR4 Cluster: Putative uncharacterized protein NCU00300.1; n=1; Neurospora crassa|Rep: Putative uncharacterized protein NCU00300.1 - Neurospora crassa Length = 538 Score = 41.5 bits (93), Expect = 0.058 Identities = 19/48 (39%), Positives = 28/48 (58%) Query: 250 EINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMG 297 ++ IS I+G + A W V F PQI NF+R S GL+ F+ + + G Sbjct: 11 DVEAISGILGSVSIACWVVVFSPQIIENFRRSSADGLSIQFIIIWLTG 58 >UniRef50_P38279 Cluster: Uncharacterized membrane protein YBR147W; n=3; Saccharomycetaceae|Rep: Uncharacterized membrane protein YBR147W - Saccharomyces cerevisiae (Baker's yeast) Length = 296 Score = 41.5 bits (93), Expect = 0.058 Identities = 32/108 (29%), Positives = 51/108 (47%), Gaps = 19/108 (17%) Query: 254 ISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLYFSKE 313 +S + G I W V F PQIY NF+R+S GL+ F+ L ++G +FN Sbjct: 13 LSGMAGSISICCWIVVFVPQIYENFRRQSAEGLSLLFIVLWLLG----DIFN---VMGAM 65 Query: 314 IQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQRV 361 +QN L P + + + A LI + QC Y++E++ + Sbjct: 66 MQN---------LLPTM---IILAAYYTLADLILLIQCMWYDKEKKSI 101 Score = 39.1 bits (87), Expect = 0.31 Identities = 19/52 (36%), Positives = 31/52 (59%) Query: 250 EINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMY 301 +IN+ + I+G++ + S PQI +NFKRKS G++F F +G T + Sbjct: 203 QINLPAQILGYLSAILYLGSRIPQIVLNFKRKSCEGVSFLFFLFACLGNTSF 254 >UniRef50_Q6ZP29 Cluster: PQ-loop repeat-containing protein 2; n=19; Euteleostomi|Rep: PQ-loop repeat-containing protein 2 - Homo sapiens (Human) Length = 291 Score = 41.5 bits (93), Expect = 0.058 Identities = 19/51 (37%), Positives = 31/51 (60%) Query: 253 IISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSL 303 +I +++G I + +S PQI NF RKS G+++ AL ++G T+Y L Sbjct: 182 VIGFVIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGL 232 >UniRef50_UPI00005A038F Cluster: PREDICTED: similar to PQ loop repeat containing 2; n=1; Canis lupus familiaris|Rep: PREDICTED: similar to PQ loop repeat containing 2 - Canis familiaris Length = 290 Score = 41.1 bits (92), Expect = 0.076 Identities = 19/51 (37%), Positives = 31/51 (60%) Query: 253 IISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSL 303 II +++G + + +S PQI NF RKS G+++ AL ++G T+Y L Sbjct: 158 IIGFVIGSVSSVLYLLSRLPQIRTNFLRKSTQGVSYSLFALVMLGNTLYGL 208 >UniRef50_Q2H971 Cluster: Putative uncharacterized protein; n=6; Pezizomycotina|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 486 Score = 41.1 bits (92), Expect = 0.076 Identities = 20/48 (41%), Positives = 28/48 (58%) Query: 250 EINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMG 297 ++ IS I G I A W V F PQI NF+R S GL+ F+ + ++G Sbjct: 11 DVEAISGICGSISIACWVVVFSPQIIENFRRGSAEGLSIQFVVVWLLG 58 Score = 36.3 bits (80), Expect = 2.2 Identities = 16/54 (29%), Positives = 28/54 (51%) Query: 250 EINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSL 303 E N++ + GW+ + S PQ+ +N++RKS G++ F +G Y L Sbjct: 241 EFNMLGQVFGWLCAVLYLGSRLPQLLLNWRRKSTEGVSVLFFLFACLGNLTYVL 294 >UniRef50_Q95XZ6 Cluster: Putative uncharacterized protein Y43H11AL.2; n=2; Caenorhabditis|Rep: Putative uncharacterized protein Y43H11AL.2 - Caenorhabditis elegans Length = 311 Score = 40.7 bits (91), Expect = 0.10 Identities = 16/50 (32%), Positives = 30/50 (60%) Query: 250 EINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFT 299 ++ ++ +I+G I A W + +PQ++ N+K K GL+ FL ++G T Sbjct: 37 DLKLLGFIIGLISLALWLIPLFPQLWQNYKTKKCEGLSLAFLFFWLVGDT 86 Score = 34.3 bits (75), Expect = 8.8 Identities = 17/47 (36%), Positives = 25/47 (53%) Query: 400 VKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVL 446 + LA+ LI PQ + NYK K G S+ +F VG ++L +L Sbjct: 48 ISLALWLIPLFPQLWQNYKTKKCEGLSLAFLFFWLVGDTCNMLGAIL 94 >UniRef50_Q75CM5 Cluster: ACL106Cp; n=1; Eremothecium gossypii|Rep: ACL106Cp - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 273 Score = 39.9 bits (89), Expect = 0.18 Identities = 29/102 (28%), Positives = 49/102 (48%), Gaps = 5/102 (4%) Query: 398 SYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNAYNY---NDW 454 S+V + +PQ NY+RKST G S +FL + L+ V + + D Sbjct: 160 SWVGASFYFFSRIPQLIKNYRRKSTDGLS-PLLFLAALTANLTYCVSVFTSCEFLASPDK 218 Query: 455 VSFFGDATKFGLGLF-SLVFDIFFILQHYVFYRNADKKYNLD 495 ++ +A F +G ++VFD+ ++ QHY YR + L+ Sbjct: 219 PAYVWNALPFIMGSGGTVVFDLIYVYQHYFLYRQKGQHKQLE 260 >UniRef50_A2EVI6 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 193 Score = 39.5 bits (88), Expect = 0.23 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 9/84 (10%) Query: 400 VKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNA-YNYNDWVSFF 458 VK I ++PQ RK+T+ SI + L F+G FL + ++L YN +W+ + Sbjct: 91 VKPVTQFISHIPQLISCITRKTTLNVSIYSQHLHFIGSFLGCIMLILEENYNITNWI-LY 149 Query: 459 GDATKFGLGLFSLVFDIFFILQHY 482 G+ F F I+F+ Y Sbjct: 150 GNT-------FIQAFSIYFLAAWY 166 >UniRef50_Q6CMA9 Cluster: Similar to sgd|S0002760 Saccharomyces cerevisiae YDR352w; n=1; Kluyveromyces lactis|Rep: Similar to sgd|S0002760 Saccharomyces cerevisiae YDR352w - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 319 Score = 39.1 bits (87), Expect = 0.31 Identities = 26/80 (32%), Positives = 42/80 (52%), Gaps = 5/80 (6%) Query: 410 VPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNAYNY---NDWVSFFGDATKFGL 466 +PQ NYKRKST G S +F+ + ++ + + +Y D + F +A F + Sbjct: 210 IPQLIKNYKRKSTDGLS-PLLFISTLIANVTYTLSIFTSCSYLTDEDKLGFVLNALPFIV 268 Query: 467 G-LFSLVFDIFFILQHYVFY 485 G ++VFD+ + QHYV Y Sbjct: 269 GSAGTVVFDLIYFYQHYVLY 288 >UniRef50_Q12010 Cluster: Uncharacterized membrane protein YOL092W; n=9; Saccharomycetales|Rep: Uncharacterized membrane protein YOL092W - Saccharomyces cerevisiae (Baker's yeast) Length = 308 Score = 39.1 bits (87), Expect = 0.31 Identities = 20/44 (45%), Positives = 26/44 (59%) Query: 254 ISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMG 297 +S I G I + W + F PQIY NF RKS GL+ F+ L + G Sbjct: 13 LSGISGSISISCWIIVFVPQIYENFYRKSSDGLSLLFVVLWLAG 56 Score = 38.3 bits (85), Expect = 0.54 Identities = 19/52 (36%), Positives = 30/52 (57%) Query: 250 EINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMY 301 +IN ++ I G++ + S PQI +NFKRKS G++F F +G T + Sbjct: 207 QINWMAQIFGYLSALLYLGSRIPQILLNFKRKSCEGISFLFFLFACLGNTTF 258 Score = 34.3 bits (75), Expect = 8.8 Identities = 26/109 (23%), Positives = 49/109 (44%), Gaps = 7/109 (6%) Query: 387 KIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVL 446 +I W+ ++ Y+ + L +PQ +N+KRKS G S +G I +++ Sbjct: 207 QINWMAQIF--GYLSALLYLGSRIPQILLNFKRKSCEGISFLFFLFACLGNTTFIFSVIV 264 Query: 447 NAYNYNDWVSFFGDATKFGLGLFSLVFDIFFILQHYVFYRNADKKYNLD 495 + DW +A+ + +L D Q +++ RN KK+ L+ Sbjct: 265 ISL---DWKYLIMNASWLVGSIGTLFMDFVIFSQFFIYKRN--KKFILN 308 >UniRef50_Q8RXY4 Cluster: Putative uncharacterized protein At2g41050; n=2; Arabidopsis thaliana|Rep: Putative uncharacterized protein At2g41050 - Arabidopsis thaliana (Mouse-ear cress) Length = 376 Score = 38.7 bits (86), Expect = 0.41 Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 1/61 (1%) Query: 246 MHSNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFN 305 +HS+ + +S +G I +W V+ PQI N+ KS GL+ FL ++G +++L Sbjct: 3 LHSSFRDGLSLSLGIISVISWGVAEIPQIMTNYSEKSTEGLSITFLTTWMIG-DIFNLLG 61 Query: 306 C 306 C Sbjct: 62 C 62 >UniRef50_A7PTI6 Cluster: Chromosome chr8 scaffold_29, whole genome shotgun sequence; n=3; Magnoliophyta|Rep: Chromosome chr8 scaffold_29, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 146 Score = 38.7 bits (86), Expect = 0.41 Identities = 20/55 (36%), Positives = 32/55 (58%), Gaps = 1/55 (1%) Query: 254 ISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGL 308 IS +G I +W+++ PQI N+K KS GL+ FL I+G ++++ C L Sbjct: 36 ISLTLGVISVISWAIAEIPQIITNYKEKSSEGLSIAFLMTWIVG-DLFNVLGCFL 89 >UniRef50_Q245B2 Cluster: Dual specificity phosphatase, catalytic domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Dual specificity phosphatase, catalytic domain containing protein - Tetrahymena thermophila SB210 Length = 373 Score = 38.7 bits (86), Expect = 0.41 Identities = 23/71 (32%), Positives = 40/71 (56%), Gaps = 2/71 (2%) Query: 125 RFCLVVMLILGIPSAHSQLDKMYVEVTDLNLLVEETRLLKLVQIGQYN-TSLEVISNIQH 183 +F V+ L+L +Q+ K+Y +V D +EE R LK + Q+N + +++IQ+ Sbjct: 126 QFHFVIALML-FTQPRTQIQKIYFQVLDCLKGIEEARRLKWIDTQQFNHIKYDHLASIQN 184 Query: 184 PDIVQLVPPSI 194 DI ++VP I Sbjct: 185 GDISEVVPNKI 195 >UniRef50_Q5A6A9 Cluster: Putative uncharacterized protein; n=2; Candida albicans|Rep: Putative uncharacterized protein - Candida albicans (Yeast) Length = 466 Score = 38.7 bits (86), Expect = 0.41 Identities = 19/61 (31%), Positives = 30/61 (49%) Query: 392 DWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNAYNY 451 DW+ V + +I +PQ NY RKST G S+ + +G ++L +V + Y Sbjct: 155 DWVQILPIVCCFLYIISRIPQIRRNYIRKSTTGLSLYMVLFTVLGTIFNLLSIVTDTNLY 214 Query: 452 N 452 N Sbjct: 215 N 215 >UniRef50_Q4WET1 Cluster: PQ loop repeat protein; n=3; Trichocomaceae|Rep: PQ loop repeat protein - Aspergillus fumigatus (Sartorya fumigata) Length = 391 Score = 38.3 bits (85), Expect = 0.54 Identities = 20/48 (41%), Positives = 28/48 (58%) Query: 250 EINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMG 297 +++ +S I G I A W V F PQI NF+R S GL+ FL + + G Sbjct: 10 DLDALSGICGSISIACWVVVFSPQIIENFRRGSADGLSLLFLVVWLAG 57 >UniRef50_A6RRJ7 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 267 Score = 38.3 bits (85), Expect = 0.54 Identities = 20/48 (41%), Positives = 27/48 (56%) Query: 250 EINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMG 297 +I IS I G I A W V F PQI N++R S GL+ F+ + + G Sbjct: 11 DITAISGICGSISIACWIVVFSPQIIENWRRGSADGLSLQFIIIWLAG 58 >UniRef50_UPI0000510461 Cluster: COG0463: Glycosyltransferases involved in cell wall biogenesis; n=1; Brevibacterium linens BL2|Rep: COG0463: Glycosyltransferases involved in cell wall biogenesis - Brevibacterium linens BL2 Length = 359 Score = 37.9 bits (84), Expect = 0.71 Identities = 28/99 (28%), Positives = 40/99 (40%), Gaps = 4/99 (4%) Query: 4 WRLVSIAHVQMLTTKRVFNPIDLAVGFGLIPFRGLLKKPCKS-SWPPH-RTWSRLVAAVG 61 WR I + R F P L +G G LL+ ++ +WP R ++ LV Sbjct: 244 WRAELIRRYGSANSLRYFAPPVLVLGMGASVIEALLQLTGRTKTWPKFLRRFTSLVHVPS 303 Query: 62 LKRAPRYRGAALSAQGC--REQRGLHTVFPFSHLCWTKG 98 L A +A+ C RE+ + P HLCW G Sbjct: 304 LGYVSAILATASAAKDCGRRERAWFGLILPTMHLCWGAG 342 >UniRef50_A7NA75 Cluster: PQ loop repeat family; n=11; Francisella tularensis|Rep: PQ loop repeat family - Francisella tularensis subsp. holarctica FTA Length = 217 Score = 37.9 bits (84), Expect = 0.71 Identities = 18/73 (24%), Positives = 39/73 (53%), Gaps = 2/73 (2%) Query: 231 PGFVNLDTVYLRITVMHS--NEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNF 288 P VN+ ++L M + + +++ + G+ F +V ++PQIY N+ +K G + Sbjct: 107 PEIVNISFIFLFAIAMLAMGSNYHLVYQLAGYFGFVINTVYWFPQIYKNYTQKRFDGFSL 166 Query: 289 DFLALNIMGFTMY 301 F+ + ++G +Y Sbjct: 167 TFILIALIGTCLY 179 >UniRef50_A2F7R5 Cluster: PQ loop repeat family protein; n=1; Trichomonas vaginalis G3|Rep: PQ loop repeat family protein - Trichomonas vaginalis G3 Length = 218 Score = 37.9 bits (84), Expect = 0.71 Identities = 59/247 (23%), Positives = 100/247 (40%), Gaps = 38/247 (15%) Query: 254 ISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGLYFSKE 313 ++ I G+ + + PQIY+NF+ KS G + + L ++G + FN L F+++ Sbjct: 6 VAKICGYASATFYFLVDLPQIYLNFRTKSTEGFSSLAVCLRMIG----NSFNFALCFAEK 61 Query: 314 IQNEYFSRHPRGLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQRVSTVGRGILGAFS 373 R L + + + F +H LI I Q F++ R + + AF Sbjct: 62 ----------RSLELIFPSLILFVVH-----LIQIFQ-FVWTRRAKPYLIFYSIPVVAFL 105 Query: 374 AVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLD 433 V ++ S + Y A +I VP Y + +ST+G S+ + L+ Sbjct: 106 VVFLIPSSNFIT------------RYFNSASQVICSVPYFYACIRIRSTLGISLFGLHLN 153 Query: 434 FVGGFLSILQMVLNAYNYN-DWVSFFGDATKFGLGLFSLVFDIFFILQHYVFYRNADKKY 492 F L IL ++N N W+ +F +G F + F Y + +A K Sbjct: 154 FTASILGILMCMINCQPDNVIWMFYFISVMYSVIG-----FGLAFAYDEYRIFDSASKHS 208 Query: 493 NLDVKSL 499 DV L Sbjct: 209 KKDVLRL 215 >UniRef50_Q0IHH3 Cluster: MGC154351 protein; n=6; Xenopus|Rep: MGC154351 protein - Xenopus laevis (African clawed frog) Length = 301 Score = 37.5 bits (83), Expect = 0.94 Identities = 17/54 (31%), Positives = 29/54 (53%) Query: 395 YYCSYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNA 448 + C + +I +I +PQ N+KRKS G ++G L +G L +V+N+ Sbjct: 189 FACGIIAYSILVIFRIPQLVSNFKRKSVEGLALGMFLLIMLGNIFYGLSIVINS 242 >UniRef50_A2QUR4 Cluster: Contig An09c0220, complete genome; n=2; Pezizomycotina|Rep: Contig An09c0220, complete genome - Aspergillus niger Length = 315 Score = 37.5 bits (83), Expect = 0.94 Identities = 20/48 (41%), Positives = 27/48 (56%) Query: 250 EINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMG 297 ++ +S I G I A W V F PQI NF+R S GL+ FL + + G Sbjct: 10 DLEALSGICGSISIACWVVVFSPQIIENFRRGSADGLSLLFLIVWLAG 57 >UniRef50_Q10482 Cluster: Seven transmembrane protein 1; n=1; Schizosaccharomyces pombe|Rep: Seven transmembrane protein 1 - Schizosaccharomyces pombe (Fission yeast) Length = 271 Score = 37.5 bits (83), Expect = 0.94 Identities = 24/95 (25%), Positives = 43/95 (45%), Gaps = 2/95 (2%) Query: 393 WLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNAYNYN 452 W + + + +PQ N+K KST G SI L VG +++ + + Sbjct: 177 WPFTAGCISSVLYFCARIPQIIKNHKAKSTEGLSIIFFVLASVGNTSYAFSILV--FPAS 234 Query: 453 DWVSFFGDATKFGLGLFSLVFDIFFILQHYVFYRN 487 D++++ + LG FS +F +I ++ YRN Sbjct: 235 DYLNYTYANLPWILGAFSTIFLDIYIFYQFIKYRN 269 >UniRef50_UPI000049838B Cluster: PQ loop repeat protein; n=1; Entamoeba histolytica HM-1:IMSS|Rep: PQ loop repeat protein - Entamoeba histolytica HM-1:IMSS Length = 320 Score = 37.1 bits (82), Expect = 1.2 Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 1/56 (1%) Query: 251 INIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNC 306 +++ SYI G I W + +PQ+Y FK K L+ FL + +G + +L C Sbjct: 29 LDVTSYIFGLINIGFWMCAQFPQLYKTFKTKKPESLSITFLVM-WLGGDITNLLGC 83 >UniRef50_O49437 Cluster: Putative uncharacterized protein AT4g20100; n=1; Arabidopsis thaliana|Rep: Putative uncharacterized protein AT4g20100 - Arabidopsis thaliana (Mouse-ear cress) Length = 288 Score = 37.1 bits (82), Expect = 1.2 Identities = 17/53 (32%), Positives = 32/53 (60%), Gaps = 1/53 (1%) Query: 254 ISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNC 306 +S +G I +WSV+ PQI N+ +KS+ G++ FL ++G ++++ C Sbjct: 6 LSLSLGIISVISWSVAEIPQIMTNYNQKSIEGVSITFLTTWMLG-DIFNVVGC 57 >UniRef50_A2WN84 Cluster: Putative uncharacterized protein; n=2; Oryza sativa|Rep: Putative uncharacterized protein - Oryza sativa subsp. indica (Rice) Length = 388 Score = 37.1 bits (82), Expect = 1.2 Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 1/51 (1%) Query: 258 MGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNCGL 308 +G + +W V+ PQI N+K KS GL+ FL I+G ++L C L Sbjct: 43 LGLLSVISWGVAEVPQIITNYKHKSTEGLSLAFLMTWIVG-DFFNLIGCFL 92 >UniRef50_Q7QXS6 Cluster: GLP_77_47661_46030; n=1; Giardia lamblia ATCC 50803|Rep: GLP_77_47661_46030 - Giardia lamblia ATCC 50803 Length = 543 Score = 37.1 bits (82), Expect = 1.2 Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 8/160 (5%) Query: 298 FTMYSLFNCGLYFSKEIQNE--YFSRHPRGLNPVQLNDVFFSL--HAAFATLITITQCFL 353 F+++ LF + + N + + P G+NP ++ ++ L A F + C+ Sbjct: 47 FSLFFLFMLPVMIPLDRANSSTFNATSPVGINPTIMSYIWVGLMLFAIFLATFLLPLCYF 106 Query: 354 YEREEQRVSTVGRGILGA-FSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQ 412 Y T+GR +LG + A VI+ ++ + + WL L + T P+ Sbjct: 107 YISSRNAGETIGRSLLGGLWKAAVIIASTLLLSAFLWWL--LEVRNTCPKQTTNALAAPE 164 Query: 413 AYMNYKRKSTVGWSIGNI-FLDFVGGFLSILQMVLNAYNY 451 + ST+ I I F F+G + +L + + + Y Sbjct: 165 RILKASTSSTMPIYIYFIVFACFLGSIIFVLFLSVGLFIY 204 >UniRef50_Q6BRI2 Cluster: Similar to CA4714|IPF5912 Candida albicans IPF5912; n=2; Saccharomycetales|Rep: Similar to CA4714|IPF5912 Candida albicans IPF5912 - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 352 Score = 37.1 bits (82), Expect = 1.2 Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 9/95 (9%) Query: 398 SYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNAYNYNDWVSF 457 S + L+ + +PQ Y NY+ KS G S + L F+G FLS +L ND V Sbjct: 15 SILSLSSWVWAQLPQIYCNYRNKSAEGISPLFLLLWFMGDFLSFTSCLL-----NDVVLK 69 Query: 458 FGDATKFGLGLFSLVFDIFFILQHYVFYRNADKKY 492 F + L LF L D+ Q+Y + +KY Sbjct: 70 F----QVYLSLFFLCNDVTLCYQYYYYNSVYPRKY 100 Score = 34.7 bits (76), Expect = 6.6 Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 5/83 (6%) Query: 246 MHSNEIN--IISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLN---FDFLALNIMGFTM 300 + S+ IN ++ + W + S PQ+Y N+KRKSV G++ F + + +T+ Sbjct: 217 LFSSSINKEVLGVFLAWSCTCVYVASRCPQLYKNYKRKSVDGISPILFGCALVGNLTYTL 276 Query: 301 YSLFNCGLYFSKEIQNEYFSRHP 323 L +C + N + P Sbjct: 277 SILTSCDFVYGDAKSNFFVKELP 299 >UniRef50_Q8C4N4 Cluster: PQ-loop repeat-containing protein 2; n=6; Euteleostomi|Rep: PQ-loop repeat-containing protein 2 - Mus musculus (Mouse) Length = 293 Score = 37.1 bits (82), Expect = 1.2 Identities = 17/51 (33%), Positives = 30/51 (58%) Query: 253 IISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSL 303 +I +++G + +S PQI NF R+S G+++ AL ++G T+Y L Sbjct: 182 VIGFVIGSASSLLYLLSRLPQIRTNFIRQSTQGISYSLFALVMLGNTLYGL 232 >UniRef50_A1L2M0 Cluster: LOC100036889 protein; n=2; Tetrapoda|Rep: LOC100036889 protein - Xenopus laevis (African clawed frog) Length = 302 Score = 36.3 bits (80), Expect = 2.2 Identities = 20/50 (40%), Positives = 26/50 (52%) Query: 252 NIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMY 301 N I + G + ++ +S PQIY NFKRKS GL L I+G Y Sbjct: 185 NKIGFACGLMSTLSYLISRLPQIYTNFKRKSTEGLAPTLFLLVIVGNVTY 234 >UniRef50_A2ETQ8 Cluster: PQ loop repeat family protein; n=2; Trichomonas vaginalis G3|Rep: PQ loop repeat family protein - Trichomonas vaginalis G3 Length = 298 Score = 36.3 bits (80), Expect = 2.2 Identities = 19/44 (43%), Positives = 24/44 (54%) Query: 254 ISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMG 297 +S+ G W + PQIYINFK KS GL+ FL I+G Sbjct: 27 LSFAFGIASTLIWMWAQLPQIYINFKIKSCDGLSLYFLLFLILG 70 >UniRef50_A2GEV7 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 621 Score = 35.9 bits (79), Expect = 2.9 Identities = 15/37 (40%), Positives = 23/37 (62%) Query: 268 VSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLF 304 V +PQ+YIN+K KSV G++F L +G + L+ Sbjct: 493 VRLFPQLYINYKLKSVAGISFTVLVYKCIGTFIDDLY 529 >UniRef50_A2FTR9 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 286 Score = 35.9 bits (79), Expect = 2.9 Identities = 18/61 (29%), Positives = 34/61 (55%), Gaps = 1/61 (1%) Query: 404 ITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNAY-NYNDWVSFFGDAT 462 I +I+Y PQ Y +K K+ SI + + GG ++ L + L + +++ W+S+ G A Sbjct: 190 IVVIQYFPQMYTTFKLKTNGSLSILMLCIQAPGGLVNSLFLWLGQHDDWSTWISYMGAAV 249 Query: 463 K 463 + Sbjct: 250 E 250 >UniRef50_A2FKL1 Cluster: PQ loop repeat family protein; n=2; Trichomonas vaginalis G3|Rep: PQ loop repeat family protein - Trichomonas vaginalis G3 Length = 289 Score = 35.9 bits (79), Expect = 2.9 Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 5/88 (5%) Query: 222 SEVTFNVTPPGFVNLDTVYLRITVMHSN---EINIISYIMGWIYFAAWSVSFYPQIYINF 278 S+ + N+ P + T + V +++ +I ++ I GWI + S PQ+ NF Sbjct: 134 SDGSDNIVAPAVAGVATAAVLAAVDYAHPYSKIELLGTIFGWISACIYISSRIPQVIKNF 193 Query: 279 KRKSVVGLNFDFLALNIMGFTMY--SLF 304 + K+V L+ ++ L+I G + Y SLF Sbjct: 194 QMKTVGDLSPFYVILSISGNSTYLISLF 221 >UniRef50_Q870T0 Cluster: Putative uncharacterized protein B1D14.050; n=4; Sordariomycetes|Rep: Putative uncharacterized protein B1D14.050 - Neurospora crassa Length = 337 Score = 35.9 bits (79), Expect = 2.9 Identities = 15/44 (34%), Positives = 25/44 (56%) Query: 254 ISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMG 297 +S + G + AW PQ+ N+K KS GL+ +FL + ++G Sbjct: 14 LSGVFGSVSLTAWICLLLPQLITNYKAKSADGLSMNFLIIWLLG 57 >UniRef50_A7TKY0 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 318 Score = 35.9 bits (79), Expect = 2.9 Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 3/89 (3%) Query: 410 VPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVL--NAYNYNDWVSFFGDATKFGLG 467 +PQ NY+RKST G S + + + + N ++ +D F +A F G Sbjct: 205 LPQLIKNYRRKSTDGISPTLFAMTLLSNITYNISIFTSCNFFDSDDKHEFIMNAMPFIFG 264 Query: 468 LFSLV-FDIFFILQHYVFYRNADKKYNLD 495 V FD+ + QHYV Y + K L+ Sbjct: 265 SAGTVAFDMIYFYQHYVLYSSDMKLRELE 293 >UniRef50_A6QV92 Cluster: Predicted protein; n=1; Ajellomyces capsulatus NAm1|Rep: Predicted protein - Ajellomyces capsulatus NAm1 Length = 358 Score = 35.9 bits (79), Expect = 2.9 Identities = 21/62 (33%), Positives = 29/62 (46%) Query: 398 SYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNAYNYNDWVSF 457 S+ + L VPQ Y NY RKST G S F F G F ++ N ++D ++ Sbjct: 191 SWSSTILYLASRVPQLYKNYGRKSTSGLSPLLFFAAFCGNFFYSSSLLTNPNAWSDLPAY 250 Query: 458 FG 459 G Sbjct: 251 GG 252 >UniRef50_Q2FLF8 Cluster: Putative uncharacterized protein; n=1; Methanospirillum hungatei JF-1|Rep: Putative uncharacterized protein - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 115 Score = 35.9 bits (79), Expect = 2.9 Identities = 19/62 (30%), Positives = 33/62 (53%) Query: 387 KIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVL 446 +I +D L Y Y+ T I ++PQ +K +S S G +FL +G FL ++ ++ Sbjct: 19 QISDMDMLLYTGYIGGICTTIAFLPQVVKTWKSRSAHDLSWGLLFLLLIGVFLWMIYGIV 78 Query: 447 NA 448 +A Sbjct: 79 SA 80 >UniRef50_UPI000023E534 Cluster: hypothetical protein FG08496.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG08496.1 - Gibberella zeae PH-1 Length = 322 Score = 35.5 bits (78), Expect = 3.8 Identities = 16/44 (36%), Positives = 25/44 (56%) Query: 254 ISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMG 297 +S I G I +W PQ++ N+K KS GL+ FL + ++G Sbjct: 22 LSGIFGSISLTSWICLLLPQLFANYKAKSADGLSMAFLIVWLLG 65 >UniRef50_Q0IHB9 Cluster: LOC779076 protein; n=5; Tetrapoda|Rep: LOC779076 protein - Xenopus laevis (African clawed frog) Length = 330 Score = 35.5 bits (78), Expect = 3.8 Identities = 25/103 (24%), Positives = 42/103 (40%), Gaps = 1/103 (0%) Query: 395 YYCSYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNAYNYNDW 454 + C YV L PQ + N+ RKST G S L +G + ++L Sbjct: 213 FICGYVSSVFYLGSRFPQLHKNFHRKSTEGTSYLLFALAMLGNCTYGMSLLLKLPAVRHL 272 Query: 455 VS-FFGDATKFGLGLFSLVFDIFFILQHYVFYRNADKKYNLDV 496 S + + +G F ++ FF+ ++ YR D+ D+ Sbjct: 273 KSQYIMHHLPWLIGSFGVLILDFFMTAQFIIYRKKDRNKTKDL 315 >UniRef50_Q1N3L8 Cluster: Putative uncharacterized protein; n=1; Oceanobacter sp. RED65|Rep: Putative uncharacterized protein - Oceanobacter sp. RED65 Length = 208 Score = 35.5 bits (78), Expect = 3.8 Identities = 19/79 (24%), Positives = 30/79 (37%), Gaps = 1/79 (1%) Query: 17 TKRVFNPIDLAVGFGLIPFRGLLKKPCKSSWPPHRTWSRLVAAVGLKRAPRYRGAALSAQ 76 T+R + + + V IP L KP K SW H W + G + +S + Sbjct: 90 TERSMDSVQIRVDIRQIPVFPLFSKPVKFSWDKHNPWHQYEQVAGYWNELEHPDQPISPK 149 Query: 77 GCREQRGLHTVFPFSHLCW 95 +HT+ H+ W Sbjct: 150 NLVRPINIHTLLQ-EHVIW 167 >UniRef50_Q01G95 Cluster: Vacuolar-type H+-pyrophosphatase; n=4; Eukaryota|Rep: Vacuolar-type H+-pyrophosphatase - Ostreococcus tauri Length = 794 Score = 35.5 bits (78), Expect = 3.8 Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 2/70 (2%) Query: 423 VGWSIGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDIFFIL--Q 480 VG ++G+ F D G L+IL ++ ++ F D T + G+F L +IF ++ Sbjct: 717 VGDTVGDPFKDTSGPALNILIKLMTIFSLTMAPVFRSDWTTWWYGVFVLCAEIFAVMVAY 776 Query: 481 HYVFYRNADK 490 +YV+ RN +K Sbjct: 777 YYVWVRNGEK 786 >UniRef50_Q54C20 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 303 Score = 35.5 bits (78), Expect = 3.8 Identities = 32/118 (27%), Positives = 51/118 (43%), Gaps = 15/118 (12%) Query: 369 LGAFSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWSIG 428 LG +SA+ ++ ++ + + Y + L I I +PQ NYK++ST G S+ Sbjct: 201 LGVYSAIFLLLTTVYLYSP----SYFEYLGTLSLTIESILGLPQLIQNYKKRSTKGLSLV 256 Query: 429 NIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDIFFILQHYVFYR 486 I F+G L + Y D S F G L+ DI LQ ++Y+ Sbjct: 257 LISSWFIGDLFKTLY-----FYYKDQPSQF-----IFCGTVQLIIDILISLQ-IIYYK 303 >UniRef50_UPI00006CF828 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 529 Score = 35.1 bits (77), Expect = 5.0 Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 12/101 (11%) Query: 156 LVEETRLLKLVQIGQYNTS-LEVISNIQHPDIVQLVPPSIEIPGSNEPNKTVVISYDICA 214 ++++ +L K+ Q+ QY S +E++ I+HP+I++LV S + + T + + C Sbjct: 44 IIKKDKLQKIPQLLQYTQSEIEIMEQIKHPNIMELV-------SSQKMDGTFFLVLEYCE 96 Query: 215 YGKSPGHSEVTFNVTPPGFVNLDTVYLRI----TVMHSNEI 251 G H + F + +L I V+HSN I Sbjct: 97 GGDLRQHIQSLIKKKELSFEQISREFLEILDAFDVLHSNHI 137 >UniRef50_Q5C6I4 Cluster: SJCHGC07693 protein; n=1; Schistosoma japonicum|Rep: SJCHGC07693 protein - Schistosoma japonicum (Blood fluke) Length = 161 Score = 35.1 bits (77), Expect = 5.0 Identities = 34/140 (24%), Positives = 58/140 (41%), Gaps = 13/140 (9%) Query: 145 KMYVEVTDLNLLV--EETRLLKLVQIGQYNTSLEVISNIQHPDIVQLVPPSIEIPGSNEP 202 K+Y + +NL + ET + L + N +LEV Q+ ++ L + P Sbjct: 26 KVYFKPKSVNLQLGENETIFIGLNDTTEINVNLEVQYWNQNSALISLEDVK---NFAIHP 82 Query: 203 NKTVVISYD------ICAYGKSPGHSEVTFNVTPP-GFVNLDTVYLRITVMHSNEINIIS 255 V+I D Y K PGH + P VN D ++V+H + + I+ Sbjct: 83 INNVIIQKDQKGPSRTIVYAKKPGHIYLGIKSVPNIHIVNADKPITPVSVIHYHWLYILQ 142 Query: 256 YIMGWIYFAAWSVSFYPQIY 275 ++GW+ YPQ++ Sbjct: 143 IVIGWL-ICCLDCFIYPQLF 161 >UniRef50_Q4D0H0 Cluster: Putative uncharacterized protein; n=2; Trypanosoma cruzi|Rep: Putative uncharacterized protein - Trypanosoma cruzi Length = 340 Score = 35.1 bits (77), Expect = 5.0 Identities = 20/86 (23%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Query: 362 STVGRGILGAFSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKS 421 S + R +L ++V A +G + W Y+ L I + +PQ N++R+S Sbjct: 194 SFIRRYVLWTLLTTILVLLYYATIGTV-WGAAPEVVGYIALGIEALLVLPQILRNHRRQS 252 Query: 422 TVGWSIGNIFLDFVGGFLSILQMVLN 447 T G +I + F+G + ++ +++ Sbjct: 253 TEGLTIMLVLTWFLGDIIKVIYFLVD 278 >UniRef50_Q1DKV8 Cluster: Putative uncharacterized protein; n=1; Coccidioides immitis|Rep: Putative uncharacterized protein - Coccidioides immitis Length = 441 Score = 35.1 bits (77), Expect = 5.0 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 3/60 (5%) Query: 398 SYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNAYNYNDWVSF 457 S+ + L +PQ + NY+RKST G S F F G F ++ N N W F Sbjct: 271 SWTSTIMYLASRLPQIFKNYRRKSTTGLSPLLFFAAFCGNFFYSTSLLTNP---NAWFDF 327 >UniRef50_A3LPY7 Cluster: Predicted protein; n=3; Saccharomycetaceae|Rep: Predicted protein - Pichia stipitis (Yeast) Length = 331 Score = 35.1 bits (77), Expect = 5.0 Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 9/85 (10%) Query: 410 VPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLF 469 +PQ NYK KS G S + L F+G FLS +L ND V F + L +F Sbjct: 27 LPQIIENYKNKSAEGISPTFLLLWFMGDFLSFTSCLL-----NDVVLQF----QIYLSIF 77 Query: 470 SLVFDIFFILQHYVFYRNADKKYNL 494 L DI Q+Y + +K+ L Sbjct: 78 FLCNDITLCFQYYYYNSVYPRKHGL 102 >UniRef50_Q9KBB5 Cluster: Sensor protein; n=1; Bacillus halodurans|Rep: Sensor protein - Bacillus halodurans Length = 914 Score = 34.7 bits (76), Expect = 6.6 Identities = 15/40 (37%), Positives = 21/40 (52%) Query: 389 EWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWSIG 428 EW L Y SY L++ + +V + NYKR +V W G Sbjct: 147 EWFIKLAYLSYTGLSLFFLLFVRYLFSNYKRNQSVRWISG 186 >UniRef50_Q8VSZ3 Cluster: AgrC; n=2; Staphylococcus caprae|Rep: AgrC - Staphylococcus caprae Length = 225 Score = 34.7 bits (76), Expect = 6.6 Identities = 33/126 (26%), Positives = 59/126 (46%), Gaps = 6/126 (4%) Query: 372 FSAVVIVTGSIAVVGKIEWLDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNIF 431 F V+++T S KIE+ +Y S+V I L+ Y + +N +KS + +S ++ Sbjct: 91 FITVLLITFSEKFSDKIEYKFIIYIVSFVGFGI-LLSYATKFLINLIKKSYL-YS-NKLY 147 Query: 432 LDFVGGFLSILQMVLNAYNYNDWVSF--FGDATKFGLGLFSLVFDIFFILQHYVFYRNAD 489 + + FL I +L + N+ + F F T +G+ ++ I I+ Y R Sbjct: 148 ISTISIFLVITFFILFIFTRNEDLDFQTFRLYTYLYVGIVLIILIILIIIS-YTVLREMK 206 Query: 490 KKYNLD 495 K NL+ Sbjct: 207 YKRNLE 212 >UniRef50_A7PV16 Cluster: Chromosome chr4 scaffold_32, whole genome shotgun sequence; n=3; core eudicotyledons|Rep: Chromosome chr4 scaffold_32, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 381 Score = 34.7 bits (76), Expect = 6.6 Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 1/52 (1%) Query: 255 SYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFNC 306 S+ G I W V+ PQI NF+ KS G++ FL I G +++L C Sbjct: 33 SFGFGLISLVCWGVAEIPQIITNFRTKSSHGVSLAFLLTWIAG-DVFNLVGC 83 >UniRef50_Q1EQ45 Cluster: EhSec24D; n=2; Entamoeba histolytica|Rep: EhSec24D - Entamoeba histolytica Length = 708 Score = 34.7 bits (76), Expect = 6.6 Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 7/79 (8%) Query: 293 LNIMGFTMYSLFN--CGL---YFSKEIQNEYFS--RHPRGLNPVQLNDVFFSLHAAFATL 345 LN G T+ S+ CGL SK++ YF+ + P L P ND + + + + Sbjct: 246 LNARGGTIISVCGTKCGLGKGVLSKKVNENYFNSTQEPILLQPDHSNDFYQKIALHCSAV 305 Query: 346 ITITQCFLYEREEQRVSTV 364 T+ FL+E E+ V T+ Sbjct: 306 NTVVHMFLFENEDLNVPTI 324 >UniRef50_A5K509 Cluster: PQ loop repeat family protein; n=1; Plasmodium vivax|Rep: PQ loop repeat family protein - Plasmodium vivax Length = 176 Score = 34.7 bits (76), Expect = 6.6 Identities = 17/51 (33%), Positives = 26/51 (50%) Query: 401 KLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNAYNY 451 K + + + VPQ Y+NYK +ST S + L F G I ++ N N+ Sbjct: 103 KYSNSCLSKVPQIYVNYKNQSTGNLSFASYLLIFCGNLARIYIILFNVENW 153 >UniRef50_A3GHF7 Cluster: Putative uncharacterized protein; n=1; Pichia stipitis|Rep: Putative uncharacterized protein - Pichia stipitis (Yeast) Length = 1034 Score = 34.7 bits (76), Expect = 6.6 Identities = 15/54 (27%), Positives = 32/54 (59%), Gaps = 2/54 (3%) Query: 150 VTDLNLLVEETR--LLKLVQIGQYNTSLEVISNIQHPDIVQLVPPSIEIPGSNE 201 + +LNL+++E + L + ++I Q+N L ++ N+ + + P + + GSNE Sbjct: 974 LNELNLMIDEFKNFLKRRIEIDQFNQDLSMVQNLTEFTYFKKIIPFLSVDGSNE 1027 >UniRef50_UPI0000E47FB1 Cluster: PREDICTED: hypothetical protein, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein, partial - Strongylocentrotus purpuratus Length = 154 Score = 34.3 bits (75), Expect = 8.8 Identities = 17/57 (29%), Positives = 34/57 (59%), Gaps = 6/57 (10%) Query: 162 LLKLVQIGQYNTSLEVISNIQHPDIVQ--LVPPSIEIPGSNEPNKTVVISYDICAYG 216 +L+L + ++ +E + N++HP+IVQ VPP +E +PN+ ++ + C+ G Sbjct: 45 ILQLENLKRWRDEVEFMRNLEHPNIVQGRPVPPELEA----KPNEPPCLAMEFCSRG 97 >UniRef50_UPI0000499C8C Cluster: hypothetical protein 168.t00007; n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical protein 168.t00007 - Entamoeba histolytica HM-1:IMSS Length = 495 Score = 34.3 bits (75), Expect = 8.8 Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 2/96 (2%) Query: 85 HTVFPFSHLCWTKGKQITMAECSAVLRPRAAACSISSHRIRFCLVVMLILGIPSAHSQLD 144 H + P + T K IT CS + P A+ +SS IR C V + +PS + L+ Sbjct: 331 HYLQPSCFILPTSLKTITFTNCSNITLPNLASIHLSSFSIRNCSTVQSLF-LPSTLTFLE 389 Query: 145 KMYVEV-TDLNLLVEETRLLKLVQIGQYNTSLEVIS 179 + LNL + + + L +VQ + + +S Sbjct: 390 IRNTPLKASLNLELIQLKQLSIVQCSSLESIIVPLS 425 >UniRef50_Q9RS20 Cluster: Multidrug-efflux transporter, putative; n=2; Deinococcus|Rep: Multidrug-efflux transporter, putative - Deinococcus radiodurans Length = 410 Score = 34.3 bits (75), Expect = 8.8 Identities = 38/151 (25%), Positives = 67/151 (44%), Gaps = 17/151 (11%) Query: 325 GLNPVQLNDVFFSLHAAFATLITITQCFLYEREEQRVSTVGRGILGAFSAVVIVTGSIAV 384 G P Q+ +F S A + + +RV+ +G G++ F+A ++GSI Sbjct: 60 GATPTQVELLFTSYLGVMAVMTLFAGNIGAKLGRKRVALIGLGLIALFAAACGLSGSIPA 119 Query: 385 VGKIE--W--LDWLYYCSYVKLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLS 440 + W L+ + + L + LI + +A M Y+ +G S+G + +GG Sbjct: 120 LAVFRGGWGLGSALFTPTALVLLLALIGHAEKAIMRYEAAIGLGMSMGPL----LGG--- 172 Query: 441 ILQMVLNAYNYNDWVSFFGDATKFGLGLFSL 471 VL ++++ FFG AT L L S+ Sbjct: 173 ----VLGSHSWR--FPFFGAATLMLLALASV 197 >UniRef50_A4CAG3 Cluster: Putative uncharacterized protein; n=1; Pseudoalteromonas tunicata D2|Rep: Putative uncharacterized protein - Pseudoalteromonas tunicata D2 Length = 223 Score = 34.3 bits (75), Expect = 8.8 Identities = 44/181 (24%), Positives = 83/181 (45%), Gaps = 22/181 (12%) Query: 285 GLNFDFLALNIMGFTMYSLFNCGLYFSKEIQNEYFSRHPRGLNPVQLNDVFFSLHAAFAT 344 GL FLAL +G +Y +S E+ ++ N + + V+FS++A F Sbjct: 9 GLCAIFLALIYIGAFIYFGAFWAYPYSAEVADQIVYLED---NHISIGIVYFSIYALFGV 65 Query: 345 LITITQCFLYER----EEQRVSTVGRGILGAFSAVVIVTGSIAVVGKIEWLDWLYYCSYV 400 ++++ LYE+ + Q +S + + +VI +G I+V+G LD + V Sbjct: 66 VLSVLVLGLYEKHSTLKTQYLSKLATLFGVVWVGLVIASGFISVIG----LD-----AVV 116 Query: 401 KLAITLIKYVPQAYMNYKRKSTVGWSIGNIFLDFVGGFLSILQMVLNAYN--YNDWVSFF 458 LA T ++ + + + T GN + VGG +L + N Y+ ++ W+++ Sbjct: 117 NLARTNVEKASETW-HIVTLLTESLGGGN---ELVGGIWVLLISLCNLYSKIFSKWLNYI 172 Query: 459 G 459 G Sbjct: 173 G 173 >UniRef50_A4RW10 Cluster: Predicted protein; n=1; Ostreococcus lucimarinus CCE9901|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 260 Score = 34.3 bits (75), Expect = 8.8 Identities = 18/71 (25%), Positives = 37/71 (52%), Gaps = 3/71 (4%) Query: 240 YLRITVMH--SNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMG 297 ++R+T S+++ + + + + A W + PQ+ +N++ KS GL+ FL L + Sbjct: 3 WIRVTFRECVSDDVQLAGFYLALVTIACWMSAQVPQLVLNYRAKSARGLSPYFL-LQWLA 61 Query: 298 FTMYSLFNCGL 308 ++L C L Sbjct: 62 GDSFNLIGCVL 72 >UniRef50_Q7RE63 Cluster: Putative uncharacterized protein PY05204; n=1; Plasmodium yoelii yoelii|Rep: Putative uncharacterized protein PY05204 - Plasmodium yoelii yoelii Length = 420 Score = 34.3 bits (75), Expect = 8.8 Identities = 15/44 (34%), Positives = 28/44 (63%) Query: 460 DATKFGLGLFSLVFDIFFILQHYVFYRNADKKYNLDVKSLIHSF 503 +A KF G+ +LV + I+Q+ +YR +K+Y D+K + +S+ Sbjct: 340 NAMKFYKGIQTLVHEKNIIIQYMAYYRKLNKQYIKDIKDIQNSY 383 >UniRef50_A2EC37 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 501 Score = 34.3 bits (75), Expect = 8.8 Identities = 16/68 (23%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Query: 142 QLDKMYVEVTDLNLLVEETRLLKLVQIGQYNTSLEVISNIQHPDIVQLVPPSIEIPGSNE 201 ++ + +E++ +N + +T L++ + Y S + +I +PD + + S+E P NE Sbjct: 251 KIGDILIEISQINEISIKTSLVRFISTVSYYHSSHQLGSILNPDFISYICCSLE-PDRNE 309 Query: 202 PNKTVVIS 209 N T+ ++ Sbjct: 310 LNNTIFMA 317 >UniRef50_Q6CAK3 Cluster: Similar to tr|Q06328 Saccharomyces cerevisiae YDR352w; n=1; Yarrowia lipolytica|Rep: Similar to tr|Q06328 Saccharomyces cerevisiae YDR352w - Yarrowia lipolytica (Candida lipolytica) Length = 324 Score = 34.3 bits (75), Expect = 8.8 Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 2/91 (2%) Query: 246 MHSNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVVGLNFDFLALNIMGFTMYSLFN 305 M + +IS + + W V+ Q Y NF+ K V G +F FL I G T ++L+ Sbjct: 1 MREEALKLISQGLTQLCIVIWVVALAYQCYANFRNKRVDGFSFGFLLCWIGGDT-FALWG 59 Query: 306 CGLYFSKEIQNEYFSRHPRGLNPVQLNDVFF 336 L Q + + + G++ + L+ F+ Sbjct: 60 ALLTHQLPFQ-IFLATYYCGIDAILLSQYFY 89 >UniRef50_Q08022 Cluster: Inner membrane protein yjgN; n=10; Enterobacteriaceae|Rep: Inner membrane protein yjgN - Salmonella typhimurium Length = 395 Score = 34.3 bits (75), Expect = 8.8 Identities = 17/57 (29%), Positives = 32/57 (56%), Gaps = 2/57 (3%) Query: 421 STVGWSIGNIFLDFVG-GFLSILQM-VLNAYNYNDWVSFFGDATKFGLGLFSLVFDI 475 S V ++G + V G L+I+ + V+N Y+ W++ FG+ FG+ FS+ ++ Sbjct: 165 SLVTIAVGGLVFSIVFLGLLAIIGIGVINGITYSKWMTLFGNGANFGIHRFSIQVNV 221 >UniRef50_P34856 Cluster: NADH-ubiquinone oxidoreductase chain 6; n=59; Endopterygota|Rep: NADH-ubiquinone oxidoreductase chain 6 - Anopheles gambiae (African malaria mosquito) Length = 174 Score = 34.3 bits (75), Expect = 8.8 Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 1/55 (1%) Query: 425 WSIGNIFLDFVGGFLSILQMVLNAYNYNDWVSFFGDATKFGLGLFSLVFDIFFIL 479 W +FL F+GG L IL + + + + N+ + T F L LFSL IFFIL Sbjct: 49 WFSYVLFLIFLGGML-ILFIYVTSLSSNEMFTMSFKLTMFSLVLFSLSMVIFFIL 102 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.325 0.139 0.432 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 613,399,357 Number of Sequences: 1657284 Number of extensions: 24746068 Number of successful extensions: 75290 Number of sequences better than 10.0: 100 Number of HSP's better than 10.0 without gapping: 63 Number of HSP's successfully gapped in prelim test: 37 Number of HSP's that attempted gapping in prelim test: 75042 Number of HSP's gapped (non-prelim): 218 length of query: 566 length of database: 575,637,011 effective HSP length: 105 effective length of query: 461 effective length of database: 401,622,191 effective search space: 185147830051 effective search space used: 185147830051 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 40 (21.6 bits) S2: 75 (34.3 bits)
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