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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000220-TA|BGIBMGA000220-PA|IPR003439|ABC transporter
related, IPR013525|ABC-2 type transporter
         (823 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC113657-1|AAI13658.1|  673|Homo sapiens ATP-binding cassette, s...   173   2e-42
AF351824-1|AAK84663.1|  672|Homo sapiens sterolin-2 protein.          173   2e-42
AF324494-1|AAK84078.1|  673|Homo sapiens sterolin-2 protein.          173   2e-42
AF320294-1|AAG40004.1|  673|Homo sapiens ABCG8 protein.               173   2e-42
AC108476-2|AAY24011.1|  673|Homo sapiens unknown protein.             173   2e-42
BC092408-1|AAH92408.1|  611|Homo sapiens ABCG2 protein protein.       144   1e-33
AY289766-1|AAP44087.1|  655|Homo sapiens ABC transporter protein.     144   1e-33
AF463519-1|AAO14617.1|  655|Homo sapiens ATP-binding cassette pr...   144   1e-33
AF103796-1|AAD09188.1|  655|Homo sapiens placenta-specific ATP-b...   144   1e-33
DQ996467-1|ABI97388.1|  655|Homo sapiens ATP-binding cassette, s...   144   1e-33
BC021281-1|AAH21281.1|  655|Homo sapiens ATP-binding cassette, s...   144   1e-33
AY333756-1|AAQ92942.1|  655|Homo sapiens ATP-binding cassette su...   144   1e-33
AY333755-1|AAQ92941.1|  655|Homo sapiens mutant ATP-binding cass...   144   1e-33
AY017168-1|AAG52982.1|  655|Homo sapiens ABC transporter ABCG2 p...   144   1e-33
AF098951-1|AAC97367.1|  655|Homo sapiens breast cancer resistanc...   144   1e-33
AC097484-1|AAY40902.1|  607|Homo sapiens unknown protein.             144   1e-33
AB056867-1|BAB39212.1|  655|Homo sapiens Breast Cancer Resistanc...   144   1e-33
AB051855-1|BAB46933.1|  655|Homo sapiens ATP-binding cassette su...   144   1e-33
AF320293-1|AAG40003.1|  651|Homo sapiens ABCG5 protein.               132   4e-30
AF312715-1|AAG53099.1|  651|Homo sapiens sterolin protein.            132   4e-30
AC108476-1|AAY24010.1|  549|Homo sapiens unknown protein.             132   4e-30
AY288307-1|AAP31310.1|  541|Homo sapiens ATP-binding cassette su...   126   3e-28
X91249-1|CAA62631.1|  674|Homo sapiens white protein.                 122   7e-27
U34919-1|AAC51098.1|  638|Homo sapiens white homolog protein.         122   7e-27
BC029158-1|AAH29158.2|  666|Homo sapiens ATP-binding cassette, s...   122   7e-27
AY048757-1|AAL06598.1|  785|Homo sapiens ATP-binding cassette tr...   122   7e-27
AP001746-1|BAA95530.1|  674|Homo sapiens white protein homolog (...   122   7e-27
AJ289137-1|CAC00730.1|  674|Homo sapiens ATP-binding cassette tr...   122   7e-27
AF323664-1|AAK28842.1|  677|Homo sapiens ATP-binding cassette tr...   122   7e-27
AF323663-1|AAK28841.1|  662|Homo sapiens ATP-binding cassette tr...   122   7e-27
AF323662-1|AAK28840.1|  663|Homo sapiens ATP-binding cassette tr...   122   7e-27
AF323661-1|AAK28839.1|  644|Homo sapiens ATP-binding cassette tr...   122   7e-27
AF323660-1|AAK28838.1|  668|Homo sapiens ATP-binding cassette tr...   122   7e-27
AF323658-5|AAK28834.1|  644|Homo sapiens ATP-binding cassette tr...   122   7e-27
AF323658-4|AAK28836.1|  677|Homo sapiens ATP-binding cassette tr...   122   7e-27
AF323658-3|AAK28837.1|  662|Homo sapiens ATP-binding cassette tr...   122   7e-27
AF323658-2|AAK28835.1|  663|Homo sapiens ATP-binding cassette tr...   122   7e-27
AF323658-1|AAK28833.1|  668|Homo sapiens ATP-binding cassette tr...   122   7e-27
AB038161-1|BAB13728.2|  674|Homo sapiens ABC transporter protein.     122   7e-27
BC041091-1|AAH41091.1|  646|Homo sapiens ATP-binding cassette, s...   116   3e-25
AJ308237-1|CAC87131.1|  646|Homo sapiens ABC transporter protein.     116   3e-25
AJ300465-1|CAC17140.1|  627|Homo sapiens putative white family A...   116   3e-25
AK002040-1|BAA92050.1|  456|Homo sapiens protein ( Homo sapiens ...    88   1e-16
AF356348-1|AAL35305.1|  103|Homo sapiens breast cancer resistanc...    68   2e-10
AF000148-1|AAC23915.1| 2273|Homo sapiens ATP-binding cassette tr...    60   2e-08
Y15635-1|CAA75729.1| 2273|Homo sapiens ABCR protein.                   60   4e-08
AF001945-1|AAC05632.1| 2273|Homo sapiens rim ABC transporter pro...    60   4e-08
AB210040-1|BAE06122.1| 2303|Homo sapiens ABCA4 variant protein p...    60   4e-08
U88667-1|AAC51144.1| 2273|Homo sapiens ATP-binding cassette tran...    56   4e-07
BC125232-1|AAI25233.1| 1500|Homo sapiens ABCA6 protein protein.        56   5e-07
BC125231-1|AAI25232.1| 1500|Homo sapiens ABCA6 protein protein.        56   5e-07
AY028898-1|AAK30023.1| 1617|Homo sapiens ATP-binding cassette A6...    56   5e-07
AF373328-1|AAM77558.1| 1617|Homo sapiens ABC transporter ABCA6 p...    56   5e-07
AF373290-1|AAM77557.1| 1617|Homo sapiens ABC transporter ABCA6 p...    56   5e-07
AF327705-1|AAK14335.1| 2436|Homo sapiens ABC transporter ABCA2 p...    56   5e-07
AY204751-1|AAP13576.1| 5058|Homo sapiens ABC A13 protein.              56   7e-07
AK131360-1|BAD18512.1| 1186|Homo sapiens  mRNA.  protein.              56   7e-07
BC008755-1|AAH08755.1|  867|Homo sapiens ABCA2 protein protein.        55   9e-07
AL807752-22|CAI12768.1| 2435|Homo sapiens ATP-binding cassette, ...    55   9e-07
AL807752-20|CAI12766.1|  226|Homo sapiens ATP-binding cassette, ...    55   9e-07
AL162060-1|CAB82398.1|  373|Homo sapiens hypothetical protein pr...    55   9e-07
AF501281-1|AAO59914.1| 2127|Homo sapiens ATP binding cassette tr...    55   9e-07
AF327657-1|AAK14334.1| 2436|Homo sapiens ABC transporter ABCA2 p...    55   9e-07
AF178941-1|AAG09372.1| 2436|Homo sapiens ATP-binding cassette su...    55   9e-07
AB028985-1|BAA83014.2| 1771|Homo sapiens KIAA1062 protein protein.     55   9e-07
AY028899-1|AAK30024.1| 1624|Homo sapiens ATP-binding cassette A9...    53   4e-06
BC130280-1|AAI30281.1| 1621|Homo sapiens ABCA8 protein protein.        53   5e-06
AB020629-1|BAA74845.2| 1591|Homo sapiens KIAA0822 protein protein.     53   5e-06
AK074491-1|BAC11021.1|  483|Homo sapiens protein ( Homo sapiens ...    52   6e-06
AK057068-1|BAB71359.1|  856|Homo sapiens protein ( Homo sapiens ...    52   6e-06
AF423346-1|AAN32752.1| 1624|Homo sapiens ATP-binding cassette su...    52   6e-06
AF423307-1|AAN32751.1| 1624|Homo sapiens ATP-binding cassette su...    52   6e-06
AL359846-6|CAH73579.1| 2261|Homo sapiens ATP-binding cassette, s...    52   8e-06
AL353685-3|CAH72444.1| 2261|Homo sapiens ATP-binding cassette, s...    52   8e-06
AK130814-1|BAC85435.1|  546|Homo sapiens protein ( Homo sapiens ...    52   8e-06
AJ012376-1|CAA10005.1| 2201|Homo sapiens ATP-binding cassette tr...    52   8e-06
AF285167-1|AAF98175.1| 2261|Homo sapiens ATP-binding cassette tr...    52   8e-06
AF275948-1|AAF86276.1| 2261|Homo sapiens ABCA1 protein.                52   8e-06
AF165281-1|AAD49849.1| 2201|Homo sapiens ATP cassette binding tr...    52   8e-06
AB055982-1|BAB63210.1| 2261|Homo sapiens ABCA1 protein.                52   8e-06
AK097296-1|BAC04994.1|  815|Homo sapiens protein ( Homo sapiens ...    52   1e-05
AF287262-1|AAK43526.1| 2261|Homo sapiens ATP-binding cassette 1 ...    52   1e-05
X97187-1|CAA65825.1| 1704|Homo sapiens ABC-C transporter protein.      51   2e-05
U78735-1|AAC50967.1| 1704|Homo sapiens ABC3 protein.                   51   2e-05
DQ073080-1|AAY57325.1| 1704|Homo sapiens ATP-binding cassette, s...    51   2e-05
AY247105-1|AAO72160.1| 1543|Homo sapiens ATP-binding cassette su...    51   2e-05
AY247065-1|AAO72161.1| 1543|Homo sapiens ATP-binding cassette su...    51   2e-05
AY028900-1|AAK30025.1| 1543|Homo sapiens ATP-binding cassette A1...    51   2e-05
AB210044-1|BAE06126.1| 1708|Homo sapiens ABCA3 variant protein p...    51   2e-05
AB070929-1|BAB86781.1| 1704|Homo sapiens lamellar body membrane ...    51   2e-05
AF328787-1|AAK00959.1| 2146|Homo sapiens ABC transporter member ...    50   3e-05
AF311102-1|AAN04657.1| 2146|Homo sapiens ABC transporter ABCA7 p...    50   3e-05
AF250238-1|AAF85794.1| 2146|Homo sapiens macrophage ABC transpor...    50   3e-05
AB055390-1|BAB62294.1| 2008|Homo sapiens ABCA-SSN protein.             50   3e-05
AK128570-1|BAC87504.1|  851|Homo sapiens protein ( Homo sapiens ...    50   3e-05
AY219711-1|AAP21093.1| 2595|Homo sapiens ABCA12 transporter subf...    48   2e-04
AY033486-1|AAK54355.1| 2277|Homo sapiens ATP-binding cassette tr...    48   2e-04
AF418105-1|AAN40735.1| 2347|Homo sapiens ATP-binding cassette tr...    48   2e-04
AB177854-1|BAD66832.1| 1440|Homo sapiens KIAA1062 splice variant...    48   2e-04
AC072062-1|AAY24276.1| 2413|Homo sapiens unknown protein.              47   3e-04
BC051320-1|AAH51320.1|  419|Homo sapiens ABCA10 protein protein.       46   7e-04
AF165306-1|AAD49852.1|  849|Homo sapiens ATP cassette binding tr...    45   0.001
BX640746-1|CAE45856.1|  431|Homo sapiens hypothetical protein pr...    45   0.001
AY028897-1|AAK30022.1| 1642|Homo sapiens ATP-binding cassette A5...    45   0.001
AJ512612-1|CAD54757.1|  925|Homo sapiens ABCA5 transporter protein.    45   0.001
AJ275973-1|CAB93535.3| 1642|Homo sapiens ATP-binding cassette pr...    45   0.001
BT009918-1|AAP88920.1|  753|Homo sapiens ATP-binding cassette, s...    44   0.002
BC006323-1|AAH06323.1|  753|Homo sapiens ATP-binding cassette, s...    44   0.002
AL360179-2|CAH70565.1|  752|Homo sapiens ATP-binding cassette, s...    44   0.002
AL360179-1|CAH70564.1|  753|Homo sapiens ATP-binding cassette, s...    44   0.002
AL359545-2|CAI41573.1|  752|Homo sapiens ATP-binding cassette, s...    44   0.002
AL359545-1|CAI41574.1|  753|Homo sapiens ATP-binding cassette, s...    44   0.002
AF241887-1|AAK20173.1|  752|Homo sapiens ATP binding cassette 7 ...    44   0.002
AF133659-1|AAD33045.1|  752|Homo sapiens ATP-binding cassette 7 ...    44   0.002
AB005289-1|BAA28861.1|  752|Homo sapiens ABC transporter 7 prote...    44   0.002
AF078777-1|AAD47141.1|  748|Homo sapiens ABC transporter protein.      44   0.003
BC131732-1|AAI31733.1| 1503|Homo sapiens ATP-binding cassette, s...    41   0.016
AF076622-1|AAC79696.1| 1503|Homo sapiens MRP6 protein.                 41   0.016
M23234-1|AAA36207.1| 1279|Homo sapiens protein ( Human membrane ...    41   0.021
AF168791-1|AAD51293.1| 1503|Homo sapiens multi-specific organic ...    40   0.036
X95715-1|CAA65019.1|  453|Homo sapiens anthracycline resistance ...    40   0.047
U18236-1|AAA84437.2|  131|Homo sapiens ATP-binding cassette prot...    40   0.047
M29447-1|AAA59576.1| 1280|Homo sapiens P glycoprotein protein.         39   0.083
M14758-1|AAA59575.1| 1280|Homo sapiens PGY1 protein.                   39   0.083
BC130424-1|AAI30425.1| 1280|Homo sapiens ATP-binding cassette, s...    39   0.083
BC051884-1|AAH51884.2|  709|Homo sapiens ATP-binding cassette, s...    39   0.083
BC051754-1|AAH51754.1|  709|Homo sapiens ATP-binding cassette, s...    39   0.083
BC009253-1|AAH09253.1|  709|Homo sapiens ATP-binding cassette, s...    39   0.083
AY910577-1|AAW82430.1| 1280|Homo sapiens ATP-binding cassette, s...    39   0.083
AK092415-1|BAC03881.1|  703|Homo sapiens protein ( Homo sapiens ...    39   0.083
AK024758-1|BAB14989.1|  390|Homo sapiens protein ( Homo sapiens ...    39   0.083
AK002060-1|BAA92063.1|  709|Homo sapiens protein ( Homo sapiens ...    39   0.083
AF016535-1|AAB69423.1| 1279|Homo sapiens P-glycoprotein protein.       39   0.083
AB208970-1|BAD92207.1| 1062|Homo sapiens Multidrug resistance pr...    39   0.083
AL137481-1|CAB70762.1|  269|Homo sapiens hypothetical protein pr...    38   0.11 
L21207-1|AAC12905.1|  748|Homo sapiens peptide transporter protein.    37   0.25 
L21206-1|AAC12904.1|  748|Homo sapiens peptide transporter protein.    37   0.25 
L21205-1|AAC12903.1|  748|Homo sapiens peptide transporter protein.    37   0.25 
BC141836-1|AAI41837.1|  693|Homo sapiens Unknown (protein for MG...    37   0.25 
BC141814-1|AAI41815.1|  718|Homo sapiens ATP-binding cassette, s...    37   0.25 
AY523971-1|AAS55412.1|  748|Homo sapiens TAP1 protein.                 37   0.25 
AK222911-1|BAD96631.1|  718|Homo sapiens ATP-binding cassette, s...    37   0.25 
AK094636-1|BAC04392.1|  701|Homo sapiens protein ( Homo sapiens ...    37   0.25 
AK002018-1|BAA92038.1|  735|Homo sapiens protein ( Homo sapiens ...    37   0.25 
AF047690-1|AAD15748.1|  718|Homo sapiens ATP-binding cassette pr...    37   0.25 
AY523970-1|AAS55411.1|  748|Homo sapiens TAP1 protein.                 37   0.33 
AK128516-1|BAC87475.1|  788|Homo sapiens protein ( Homo sapiens ...    37   0.33 
BX248518-7|CAM26017.1|  845|Homo sapiens ATP-binding cassette su...    36   0.44 
BX248518-6|CAM26016.1|  807|Homo sapiens ATP-binding cassette su...    36   0.44 
BX119957-3|CAM25907.1|  845|Homo sapiens ATP-binding cassette su...    36   0.44 
BX119957-2|CAM25906.1|  807|Homo sapiens ATP-binding cassette su...    36   0.44 
BX000357-8|CAI18563.1|  845|Homo sapiens ATP-binding cassette, s...    36   0.44 
BX000357-6|CAI18562.1|  807|Homo sapiens ATP-binding cassette, s...    36   0.44 
BC112923-1|AAI12924.1|  845|Homo sapiens ATP-binding cassette, s...    36   0.44 
BC034488-1|AAH34488.1|  845|Homo sapiens ATP-binding cassette, s...    36   0.44 
BA000025-75|BAB63325.1|  807|Homo sapiens TNFalpha-inducible ATP...    36   0.44 
AL662825-8|CAI17836.1|  807|Homo sapiens ATP-binding cassette, s...    36   0.44 
AL662825-7|CAI17837.1|  845|Homo sapiens ATP-binding cassette, s...    36   0.44 
AL662800-8|CAI18158.1|  845|Homo sapiens ATP-binding cassette, s...    36   0.44 
AL662800-7|CAI18159.1|  807|Homo sapiens ATP-binding cassette, s...    36   0.44 
AF027302-1|AAC70891.1|  807|Homo sapiens TNF-alpha stimulated AB...    36   0.44 
AB209564-1|BAD92801.1|  593|Homo sapiens ATP-binding cassette, s...    36   0.44 
AB202093-1|BAE78612.1|  807|Homo sapiens ATP-binding cassette, s...    36   0.44 
AB103602-1|BAF31263.1|  807|Homo sapiens ABC50 protein protein.        36   0.44 
AB088096-1|BAC54928.1|  807|Homo sapiens ATP-binding cassette, s...    36   0.44 
X87344-5|CAA60785.1|  748|Homo sapiens TAP1 protein.                   35   1.0  
X66401-2|CAA47025.1|  748|Homo sapiens ABC-transporter protein.        35   1.0  
X57522-1|CAA40741.1|  808|Homo sapiens peptide transporter protein.    35   1.0  
L21208-1|AAC12906.1|  748|Homo sapiens peptide transporter protein.    35   1.0  
L21204-1|AAC12902.1|  748|Homo sapiens peptide transporter protein.    35   1.0  
BX088556-4|CAM26263.1|  808|Homo sapiens transporter 1 ATP-bindi...    35   1.0  
BC014081-1|AAH14081.1|  808|Homo sapiens transporter 1, ATP-bind...    35   1.0  
AY196326-1|AAO40749.1|  930|Homo sapiens truncated ABCC12 protei...    35   1.0  
AY040220-1|AAK76740.1| 1359|Homo sapiens ATP-binding cassette tr...    35   1.0  
AL935043-6|CAI18626.1|  808|Homo sapiens transporter 1, ATP-bind...    35   1.0  
AL671681-12|CAI17714.1|  808|Homo sapiens transporter 1, ATP-bin...    35   1.0  
AL669918-8|CAI18140.1|  808|Homo sapiens transporter 1, ATP-bind...    35   1.0  
AK058170-1|BAB71700.1|  364|Homo sapiens protein ( Homo sapiens ...    35   1.0  
AF411578-1|AAL99901.1| 1009|Homo sapiens ATP-binding cassette pr...    35   1.0  
AF411577-1|AAL99900.1| 1009|Homo sapiens ATP-binding cassette pr...    35   1.0  
AF395909-1|AAL79529.1|  935|Homo sapiens ATP-binding cassette pr...    35   1.0  
AF395908-1|AAL79528.1| 1009|Homo sapiens ATP-binding cassette pr...    35   1.0  
AB067475-1|BAB67781.1|  737|Homo sapiens KIAA1888 protein protein.     35   1.0  
AK056533-1|BAB71208.1|  865|Homo sapiens protein ( Homo sapiens ...    35   1.3  
DQ413174-1|ABD83327.1|  650|Homo sapiens actin-binding LIM prote...    34   2.4  
BC001665-1|AAH01665.1|  544|Homo sapiens ABLIM3 protein protein.       34   2.4  
AK091270-1|BAC03623.1|  293|Homo sapiens protein ( Homo sapiens ...    34   2.4  
AB020650-1|BAA74866.2|  691|Homo sapiens KIAA0843 protein protein.     34   2.4  
X76388-1|CAA53972.1|  599|Homo sapiens RNase L inhibitor protein.      33   5.4  
AL356504-1|CAI19595.1| 4061|Homo sapiens filaggrin protein.            33   5.4  
BC009062-1|AAH09062.1|  198|Homo sapiens Unknown (protein for IM...    32   7.2  
AB016092-1|BAA83718.1| 2752|Homo sapiens RNA binding protein pro...    32   7.2  
AB016091-1|BAA83717.1| 1275|Homo sapiens RNA binding protein pro...    32   7.2  
AB002322-1|BAA20782.3| 2800|Homo sapiens KIAA0324 protein protein.     32   7.2  

>BC113657-1|AAI13658.1|  673|Homo sapiens ATP-binding cassette,
           sub-family G (WHITE), member 8 (sterolin 2) protein.
          Length = 673

 Score =  173 bits (421), Expect = 2e-42
 Identities = 102/256 (39%), Positives = 152/256 (59%), Gaps = 13/256 (5%)

Query: 210 TSP--ENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVR---KKLSGDIVIN 264
           TSP  +N   L +  LSF+V+ G++LA++ ++      LLDV+ G     K  SG I IN
Sbjct: 76  TSPSCQNSCELGIQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIWIN 135

Query: 265 GQPVASSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLI 324
           GQP +   +RK VA+VR    L P ++V  TL F A +R PR T S  +  D+ R+  +I
Sbjct: 136 GQPSSPQLVRKCVAHVRQHNQLLPNLTVRETLAFIAQMRLPR-TFSQAQR-DK-RVEDVI 192

Query: 325 EELGLEQVRDTNVGR-----LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLV 379
            EL L Q  DT VG      L+  E RR+++  QLL +  ILILD+PT  +D F    LV
Sbjct: 193 AELRLRQCADTRVGNMYVRGLSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLV 252

Query: 380 EYLRNWASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCP 439
           + L   A   R+V++SLH P  +IF +   V+L+++G  ++ G  + M+ YF++I YPCP
Sbjct: 253 KTLSRLAKGNRLVLISLHQPRSDIFRLFDLVLLMTSGTPIYLGAAQHMVQYFTAIGYPCP 312

Query: 440 AFKNPSDYYLDLVTLD 455
            + NP+D+Y+DL ++D
Sbjct: 313 RYSNPADFYVDLTSID 328


>AF351824-1|AAK84663.1|  672|Homo sapiens sterolin-2 protein.
          Length = 672

 Score =  173 bits (421), Expect = 2e-42
 Identities = 102/256 (39%), Positives = 152/256 (59%), Gaps = 13/256 (5%)

Query: 210 TSP--ENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVR---KKLSGDIVIN 264
           TSP  +N   L +  LSF+V+ G++LA++ ++      LLDV+ G     K  SG I IN
Sbjct: 76  TSPSCQNSCELGIQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIWIN 135

Query: 265 GQPVASSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLI 324
           GQP +   +RK VA+VR    L P ++V  TL F A +R PR T S  +  D+ R+  +I
Sbjct: 136 GQPSSPQLVRKCVAHVRQHNQLLPNLTVRETLAFIAQMRLPR-TFSQAQR-DK-RVEDVI 192

Query: 325 EELGLEQVRDTNVGR-----LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLV 379
            EL L Q  DT VG      L+  E RR+++  QLL +  ILILD+PT  +D F    LV
Sbjct: 193 AELRLRQCADTRVGNMYVRGLSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLV 252

Query: 380 EYLRNWASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCP 439
           + L   A   R+V++SLH P  +IF +   V+L+++G  ++ G  + M+ YF++I YPCP
Sbjct: 253 KTLSRLAKGNRLVLISLHQPRSDIFRLFDLVLLMTSGTPIYLGAAQHMVQYFTAIGYPCP 312

Query: 440 AFKNPSDYYLDLVTLD 455
            + NP+D+Y+DL ++D
Sbjct: 313 RYSNPADFYVDLTSID 328


>AF324494-1|AAK84078.1|  673|Homo sapiens sterolin-2 protein.
          Length = 673

 Score =  173 bits (421), Expect = 2e-42
 Identities = 102/256 (39%), Positives = 152/256 (59%), Gaps = 13/256 (5%)

Query: 210 TSP--ENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVR---KKLSGDIVIN 264
           TSP  +N   L +  LSF+V+ G++LA++ ++      LLDV+ G     K  SG I IN
Sbjct: 76  TSPSCQNSCELGIQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIWIN 135

Query: 265 GQPVASSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLI 324
           GQP +   +RK VA+VR    L P ++V  TL F A +R PR T S  +  D+ R+  +I
Sbjct: 136 GQPSSPQLVRKCVAHVRQHNQLLPNLTVRETLAFIAQMRLPR-TFSQAQR-DK-RVEDVI 192

Query: 325 EELGLEQVRDTNVGR-----LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLV 379
            EL L Q  DT VG      L+  E RR+++  QLL +  ILILD+PT  +D F    LV
Sbjct: 193 AELRLRQCADTRVGNMYVRGLSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLV 252

Query: 380 EYLRNWASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCP 439
           + L   A   R+V++SLH P  +IF +   V+L+++G  ++ G  + M+ YF++I YPCP
Sbjct: 253 KTLSRLAKGNRLVLISLHQPRSDIFRLFDLVLLMTSGTPIYLGAAQHMVQYFTAIGYPCP 312

Query: 440 AFKNPSDYYLDLVTLD 455
            + NP+D+Y+DL ++D
Sbjct: 313 RYSNPADFYVDLTSID 328


>AF320294-1|AAG40004.1|  673|Homo sapiens ABCG8 protein.
          Length = 673

 Score =  173 bits (421), Expect = 2e-42
 Identities = 102/256 (39%), Positives = 152/256 (59%), Gaps = 13/256 (5%)

Query: 210 TSP--ENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVR---KKLSGDIVIN 264
           TSP  +N   L +  LSF+V+ G++LA++ ++      LLDV+ G     K  SG I IN
Sbjct: 76  TSPSCQNSCELGIQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIWIN 135

Query: 265 GQPVASSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLI 324
           GQP +   +RK VA+VR    L P ++V  TL F A +R PR T S  +  D+ R+  +I
Sbjct: 136 GQPSSPQLVRKCVAHVRQHNQLLPNLTVRETLAFIAQMRLPR-TFSQAQR-DK-RVEDVI 192

Query: 325 EELGLEQVRDTNVGR-----LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLV 379
            EL L Q  DT VG      L+  E RR+++  QLL +  ILILD+PT  +D F    LV
Sbjct: 193 AELRLRQCADTRVGNMYVRGLSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLV 252

Query: 380 EYLRNWASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCP 439
           + L   A   R+V++SLH P  +IF +   V+L+++G  ++ G  + M+ YF++I YPCP
Sbjct: 253 KTLSRLAKGNRLVLISLHQPRSDIFRLFDLVLLMTSGTPIYLGAAQHMVQYFTAIGYPCP 312

Query: 440 AFKNPSDYYLDLVTLD 455
            + NP+D+Y+DL ++D
Sbjct: 313 RYSNPADFYVDLTSID 328


>AC108476-2|AAY24011.1|  673|Homo sapiens unknown protein.
          Length = 673

 Score =  173 bits (421), Expect = 2e-42
 Identities = 102/256 (39%), Positives = 152/256 (59%), Gaps = 13/256 (5%)

Query: 210 TSP--ENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVR---KKLSGDIVIN 264
           TSP  +N   L +  LSF+V+ G++LA++ ++      LLDV+ G     K  SG I IN
Sbjct: 76  TSPSCQNSCELGIQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIWIN 135

Query: 265 GQPVASSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLI 324
           GQP +   +RK VA+VR    L P ++V  TL F A +R PR T S  +  D+ R+  +I
Sbjct: 136 GQPSSPQLVRKCVAHVRQHNQLLPNLTVRETLAFIAQMRLPR-TFSQAQR-DK-RVEDVI 192

Query: 325 EELGLEQVRDTNVGR-----LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLV 379
            EL L Q  DT VG      L+  E RR+++  QLL +  ILILD+PT  +D F    LV
Sbjct: 193 AELRLRQCADTRVGNMYVRGLSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLV 252

Query: 380 EYLRNWASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCP 439
           + L   A   R+V++SLH P  +IF +   V+L+++G  ++ G  + M+ YF++I YPCP
Sbjct: 253 KTLSRLAKGNRLVLISLHQPRSDIFRLFDLVLLMTSGTPIYLGAAQHMVQYFTAIGYPCP 312

Query: 440 AFKNPSDYYLDLVTLD 455
            + NP+D+Y+DL ++D
Sbjct: 313 RYSNPADFYVDLTSID 328


>BC092408-1|AAH92408.1|  611|Homo sapiens ABCG2 protein protein.
          Length = 611

 Score =  144 bits (349), Expect = 1e-33
 Identities = 84/244 (34%), Positives = 137/244 (56%), Gaps = 12/244 (4%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK--LSGDIVINGQPVASSTLRKV 276
           ++S ++  +K G + A+L       + LLDVLA  +    LSGD++ING P   +  +  
Sbjct: 63  ILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAP-RPANFKCN 120

Query: 277 VAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTN 336
             YV  D  +  T++V   L+F AALR      +H K    +RIN +I+ELGL++V D+ 
Sbjct: 121 SGYVVQDDVVMGTLTVRENLKFSAALRLATTMTNHEK---NERINRVIQELGLDKVADSK 177

Query: 337 VGR-----LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRV 391
           VG      ++  E +R ++  +L+ D +IL LD+PT  +D      ++  L+  +  GR 
Sbjct: 178 VGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRT 237

Query: 392 VIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDL 451
           +I S+H P Y IF +   + L+++GR MF G  ++ L YF S  Y C A+ NP+D++LD+
Sbjct: 238 IIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDI 297

Query: 452 VTLD 455
           +  D
Sbjct: 298 INGD 301


>AY289766-1|AAP44087.1|  655|Homo sapiens ABC transporter protein.
          Length = 655

 Score =  144 bits (349), Expect = 1e-33
 Identities = 85/244 (34%), Positives = 137/244 (56%), Gaps = 12/244 (4%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK--LSGDIVINGQPVASSTLRKV 276
           ++S ++  +K G + A+L       + LLDVLA  +    LSGD++ING P   +  +  
Sbjct: 63  ILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAP-RPANFKCN 120

Query: 277 VAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTN 336
             YV  D  +  T++V   L+F AALR      +H K    +RIN +IEELGL++V D+ 
Sbjct: 121 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEK---NERINRVIEELGLDKVADSK 177

Query: 337 VGR-----LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRV 391
           VG      ++  E +R ++  +L+ D +IL LD+PT  +D      ++  L+  +  GR 
Sbjct: 178 VGTQFIRGVSGGERKRTSIGMELITDPSILSLDEPTTGLDSSTANAVLLLLKRMSKQGRT 237

Query: 392 VIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDL 451
           +I S+H P Y IF +   + L+++GR MF G  ++ L YF S  Y C A+ NP+D++LD+
Sbjct: 238 IIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDI 297

Query: 452 VTLD 455
           +  D
Sbjct: 298 INGD 301



 Score = 32.7 bits (71), Expect = 5.4
 Identities = 14/82 (17%), Positives = 38/82 (46%)

Query: 637 DAFYIYLGCMVLFFINIQMVCRATIFLVPMEKTASVIAGVCLLLGTLVNGVMIQQADLPY 696
           DAF++ +  +++   +   +  A      +   A+++  +C +   + +G+++    +  
Sbjct: 504 DAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIAS 563

Query: 697 YVKWLQYVSPSRWTIPEILRRE 718
           ++ WLQY S  R+    +   E
Sbjct: 564 WLSWLQYFSIPRYGFTALQHNE 585


>AF463519-1|AAO14617.1|  655|Homo sapiens ATP-binding cassette
           protein ABCG2 protein.
          Length = 655

 Score =  144 bits (349), Expect = 1e-33
 Identities = 84/244 (34%), Positives = 137/244 (56%), Gaps = 12/244 (4%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK--LSGDIVINGQPVASSTLRKV 276
           ++S ++  +K G + A+L       + LLDVLA  +    LSGD++ING P   +  +  
Sbjct: 63  ILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAP-RPANFKCN 120

Query: 277 VAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTN 336
             YV  D  +  T++V   L+F AALR      +H K    +RIN +I+ELGL++V D+ 
Sbjct: 121 SGYVVQDDVVMGTLTVRENLKFSAALRLATTMTNHEK---NERINRVIQELGLDKVADSK 177

Query: 337 VGR-----LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRV 391
           VG      ++  E +R ++  +L+ D +IL LD+PT  +D      ++  L+  +  GR 
Sbjct: 178 VGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRT 237

Query: 392 VIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDL 451
           +I S+H P Y IF +   + L+++GR MF G  ++ L YF S  Y C A+ NP+D++LD+
Sbjct: 238 IIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDI 297

Query: 452 VTLD 455
           +  D
Sbjct: 298 INGD 301



 Score = 32.7 bits (71), Expect = 5.4
 Identities = 14/82 (17%), Positives = 38/82 (46%)

Query: 637 DAFYIYLGCMVLFFINIQMVCRATIFLVPMEKTASVIAGVCLLLGTLVNGVMIQQADLPY 696
           DAF++ +  +++   +   +  A      +   A+++  +C +   + +G+++    +  
Sbjct: 504 DAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIAS 563

Query: 697 YVKWLQYVSPSRWTIPEILRRE 718
           ++ WLQY S  R+    +   E
Sbjct: 564 WLSWLQYFSIPRYGFTALQHNE 585


>AF103796-1|AAD09188.1|  655|Homo sapiens placenta-specific
           ATP-binding cassette transporter protein.
          Length = 655

 Score =  144 bits (349), Expect = 1e-33
 Identities = 85/244 (34%), Positives = 137/244 (56%), Gaps = 12/244 (4%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK--LSGDIVINGQPVASSTLRKV 276
           ++S ++  +K G + A+L       + LLDVLA  +    LSGD++ING P   +  +  
Sbjct: 63  ILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAP-RPANFKCN 120

Query: 277 VAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTN 336
             YV  D  +  T++V   L+F AALR      +H K    +RIN +IEELGL++V D+ 
Sbjct: 121 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEK---NERINRVIEELGLDKVADSK 177

Query: 337 VGR-----LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRV 391
           VG      ++  E +R ++  +L+ D +IL LD+PT  +D      ++  L+  +  GR 
Sbjct: 178 VGTQFIRGVSGGERKRTSIGMELITDPSILSLDEPTTGLDSSTANAVLLLLKRMSKQGRT 237

Query: 392 VIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDL 451
           +I S+H P Y IF +   + L+++GR MF G  ++ L YF S  Y C A+ NP+D++LD+
Sbjct: 238 IIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDI 297

Query: 452 VTLD 455
           +  D
Sbjct: 298 INGD 301



 Score = 32.7 bits (71), Expect = 5.4
 Identities = 14/82 (17%), Positives = 38/82 (46%)

Query: 637 DAFYIYLGCMVLFFINIQMVCRATIFLVPMEKTASVIAGVCLLLGTLVNGVMIQQADLPY 696
           DAF++ +  +++   +   +  A      +   A+++  +C +   + +G+++    +  
Sbjct: 504 DAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIAS 563

Query: 697 YVKWLQYVSPSRWTIPEILRRE 718
           ++ WLQY S  R+    +   E
Sbjct: 564 WLSWLQYFSIPRYGFTALQHNE 585


>DQ996467-1|ABI97388.1|  655|Homo sapiens ATP-binding cassette,
           sub-family G (WHITE), member 2 protein.
          Length = 655

 Score =  144 bits (348), Expect = 1e-33
 Identities = 84/244 (34%), Positives = 137/244 (56%), Gaps = 12/244 (4%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK--LSGDIVINGQPVASSTLRKV 276
           ++S ++  +K G + A+L       + LLDVLA  +    LSGD++ING P   +  +  
Sbjct: 63  ILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAP-RPANFKCN 120

Query: 277 VAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTN 336
             YV  D  +  T++V   L+F AALR      +H K    +RIN +I+ELGL++V D+ 
Sbjct: 121 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEK---NERINRVIQELGLDKVADSK 177

Query: 337 VGR-----LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRV 391
           VG      ++  E +R ++  +L+ D +IL LD+PT  +D      ++  L+  +  GR 
Sbjct: 178 VGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRT 237

Query: 392 VIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDL 451
           +I S+H P Y IF +   + L+++GR MF G  ++ L YF S  Y C A+ NP+D++LD+
Sbjct: 238 IIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDI 297

Query: 452 VTLD 455
           +  D
Sbjct: 298 INGD 301



 Score = 32.7 bits (71), Expect = 5.4
 Identities = 14/82 (17%), Positives = 38/82 (46%)

Query: 637 DAFYIYLGCMVLFFINIQMVCRATIFLVPMEKTASVIAGVCLLLGTLVNGVMIQQADLPY 696
           DAF++ +  +++   +   +  A      +   A+++  +C +   + +G+++    +  
Sbjct: 504 DAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIAS 563

Query: 697 YVKWLQYVSPSRWTIPEILRRE 718
           ++ WLQY S  R+    +   E
Sbjct: 564 WLSWLQYFSIPRYGFTALQHNE 585


>BC021281-1|AAH21281.1|  655|Homo sapiens ATP-binding cassette,
           sub-family G (WHITE), member 2 protein.
          Length = 655

 Score =  144 bits (348), Expect = 1e-33
 Identities = 84/244 (34%), Positives = 137/244 (56%), Gaps = 12/244 (4%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK--LSGDIVINGQPVASSTLRKV 276
           ++S ++  +K G + A+L       + LLDVLA  +    LSGD++ING P   +  +  
Sbjct: 63  ILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAP-RPANFKCN 120

Query: 277 VAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTN 336
             YV  D  +  T++V   L+F AALR      +H K    +RIN +I+ELGL++V D+ 
Sbjct: 121 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEK---NERINRVIQELGLDKVADSK 177

Query: 337 VGR-----LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRV 391
           VG      ++  E +R ++  +L+ D +IL LD+PT  +D      ++  L+  +  GR 
Sbjct: 178 VGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRT 237

Query: 392 VIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDL 451
           +I S+H P Y IF +   + L+++GR MF G  ++ L YF S  Y C A+ NP+D++LD+
Sbjct: 238 IIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDI 297

Query: 452 VTLD 455
           +  D
Sbjct: 298 INGD 301



 Score = 32.7 bits (71), Expect = 5.4
 Identities = 14/82 (17%), Positives = 38/82 (46%)

Query: 637 DAFYIYLGCMVLFFINIQMVCRATIFLVPMEKTASVIAGVCLLLGTLVNGVMIQQADLPY 696
           DAF++ +  +++   +   +  A      +   A+++  +C +   + +G+++    +  
Sbjct: 504 DAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIAS 563

Query: 697 YVKWLQYVSPSRWTIPEILRRE 718
           ++ WLQY S  R+    +   E
Sbjct: 564 WLSWLQYFSIPRYGFTALQHNE 585


>AY333756-1|AAQ92942.1|  655|Homo sapiens ATP-binding cassette
           sub-family G (WHITE) member 2 protein.
          Length = 655

 Score =  144 bits (348), Expect = 1e-33
 Identities = 84/244 (34%), Positives = 137/244 (56%), Gaps = 12/244 (4%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK--LSGDIVINGQPVASSTLRKV 276
           ++S ++  +K G + A+L       + LLDVLA  +    LSGD++ING P   +  +  
Sbjct: 63  ILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAP-RPANFKCN 120

Query: 277 VAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTN 336
             YV  D  +  T++V   L+F AALR      +H K    +RIN +I+ELGL++V D+ 
Sbjct: 121 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEK---NERINRVIQELGLDKVADSK 177

Query: 337 VGR-----LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRV 391
           VG      ++  E +R ++  +L+ D +IL LD+PT  +D      ++  L+  +  GR 
Sbjct: 178 VGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRT 237

Query: 392 VIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDL 451
           +I S+H P Y IF +   + L+++GR MF G  ++ L YF S  Y C A+ NP+D++LD+
Sbjct: 238 IIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDI 297

Query: 452 VTLD 455
           +  D
Sbjct: 298 INGD 301



 Score = 32.7 bits (71), Expect = 5.4
 Identities = 14/82 (17%), Positives = 38/82 (46%)

Query: 637 DAFYIYLGCMVLFFINIQMVCRATIFLVPMEKTASVIAGVCLLLGTLVNGVMIQQADLPY 696
           DAF++ +  +++   +   +  A      +   A+++  +C +   + +G+++    +  
Sbjct: 504 DAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIAS 563

Query: 697 YVKWLQYVSPSRWTIPEILRRE 718
           ++ WLQY S  R+    +   E
Sbjct: 564 WLSWLQYFSIPRYGFTALQHNE 585


>AY333755-1|AAQ92941.1|  655|Homo sapiens mutant ATP-binding
           cassette sub-family G (WHITE) member 2 protein.
          Length = 655

 Score =  144 bits (348), Expect = 1e-33
 Identities = 84/244 (34%), Positives = 137/244 (56%), Gaps = 12/244 (4%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK--LSGDIVINGQPVASSTLRKV 276
           ++S ++  +K G + A+L       + LLDVLA  +    LSGD++ING P   +  +  
Sbjct: 63  ILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAP-RPANFKCN 120

Query: 277 VAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTN 336
             YV  D  +  T++V   L+F AALR      +H K    +RIN +I+ELGL++V D+ 
Sbjct: 121 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEK---NERINRVIQELGLDKVADSK 177

Query: 337 VGR-----LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRV 391
           VG      ++  E +R ++  +L+ D +IL LD+PT  +D      ++  L+  +  GR 
Sbjct: 178 VGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRT 237

Query: 392 VIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDL 451
           +I S+H P Y IF +   + L+++GR MF G  ++ L YF S  Y C A+ NP+D++LD+
Sbjct: 238 IIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDI 297

Query: 452 VTLD 455
           +  D
Sbjct: 298 INGD 301



 Score = 32.7 bits (71), Expect = 5.4
 Identities = 14/82 (17%), Positives = 38/82 (46%)

Query: 637 DAFYIYLGCMVLFFINIQMVCRATIFLVPMEKTASVIAGVCLLLGTLVNGVMIQQADLPY 696
           DAF++ +  +++   +   +  A      +   A+++  +C +   + +G+++    +  
Sbjct: 504 DAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIAS 563

Query: 697 YVKWLQYVSPSRWTIPEILRRE 718
           ++ WLQY S  R+    +   E
Sbjct: 564 WLSWLQYFSIPRYGFTALQHNE 585


>AY017168-1|AAG52982.1|  655|Homo sapiens ABC transporter ABCG2
           protein.
          Length = 655

 Score =  144 bits (348), Expect = 1e-33
 Identities = 84/244 (34%), Positives = 137/244 (56%), Gaps = 12/244 (4%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK--LSGDIVINGQPVASSTLRKV 276
           ++S ++  +K G + A+L       + LLDVLA  +    LSGD++ING P   +  +  
Sbjct: 63  ILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAP-RPANFKCN 120

Query: 277 VAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTN 336
             YV  D  +  T++V   L+F AALR      +H K    +RIN +I+ELGL++V D+ 
Sbjct: 121 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEK---NERINRVIQELGLDKVADSK 177

Query: 337 VGR-----LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRV 391
           VG      ++  E +R ++  +L+ D +IL LD+PT  +D      ++  L+  +  GR 
Sbjct: 178 VGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRT 237

Query: 392 VIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDL 451
           +I S+H P Y IF +   + L+++GR MF G  ++ L YF S  Y C A+ NP+D++LD+
Sbjct: 238 IIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDI 297

Query: 452 VTLD 455
           +  D
Sbjct: 298 INGD 301



 Score = 33.5 bits (73), Expect = 3.1
 Identities = 19/96 (19%), Positives = 43/96 (44%), Gaps = 4/96 (4%)

Query: 623 YAMSGLYAPTPGAFDAFYIYLGCMVLFFINIQMVCRATIFLVPMEKTASVIAGVCLLLGT 682
           Y M GL A      DAF++ +  +++   +   +  A      +   A+++  +C +   
Sbjct: 494 YFMLGLKAKA----DAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMM 549

Query: 683 LVNGVMIQQADLPYYVKWLQYVSPSRWTIPEILRRE 718
           + +G+++    +  ++ WLQY S  R+    +   E
Sbjct: 550 IFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNE 585


>AF098951-1|AAC97367.1|  655|Homo sapiens breast cancer resistance
           protein protein.
          Length = 655

 Score =  144 bits (348), Expect = 1e-33
 Identities = 84/244 (34%), Positives = 137/244 (56%), Gaps = 12/244 (4%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK--LSGDIVINGQPVASSTLRKV 276
           ++S ++  +K G + A+L       + LLDVLA  +    LSGD++ING P   +  +  
Sbjct: 63  ILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAP-RPANFKCN 120

Query: 277 VAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTN 336
             YV  D  +  T++V   L+F AALR      +H K    +RIN +I+ELGL++V D+ 
Sbjct: 121 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEK---NERINRVIQELGLDKVADSK 177

Query: 337 VGR-----LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRV 391
           VG      ++  E +R ++  +L+ D +IL LD+PT  +D      ++  L+  +  GR 
Sbjct: 178 VGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRT 237

Query: 392 VIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDL 451
           +I S+H P Y IF +   + L+++GR MF G  ++ L YF S  Y C A+ NP+D++LD+
Sbjct: 238 IIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDI 297

Query: 452 VTLD 455
           +  D
Sbjct: 298 INGD 301



 Score = 32.7 bits (71), Expect = 5.4
 Identities = 14/82 (17%), Positives = 38/82 (46%)

Query: 637 DAFYIYLGCMVLFFINIQMVCRATIFLVPMEKTASVIAGVCLLLGTLVNGVMIQQADLPY 696
           DAF++ +  +++   +   +  A      +   A+++  +C +   + +G+++    +  
Sbjct: 504 DAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIAS 563

Query: 697 YVKWLQYVSPSRWTIPEILRRE 718
           ++ WLQY S  R+    +   E
Sbjct: 564 WLSWLQYFSIPRYGFTALQHNE 585


>AC097484-1|AAY40902.1|  607|Homo sapiens unknown protein.
          Length = 607

 Score =  144 bits (348), Expect = 1e-33
 Identities = 84/244 (34%), Positives = 137/244 (56%), Gaps = 12/244 (4%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK--LSGDIVINGQPVASSTLRKV 276
           ++S ++  +K G + A+L       + LLDVLA  +    LSGD++ING P   +  +  
Sbjct: 63  ILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAP-RPANFKCN 120

Query: 277 VAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTN 336
             YV  D  +  T++V   L+F AALR      +H K    +RIN +I+ELGL++V D+ 
Sbjct: 121 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEK---NERINRVIQELGLDKVADSK 177

Query: 337 VGR-----LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRV 391
           VG      ++  E +R ++  +L+ D +IL LD+PT  +D      ++  L+  +  GR 
Sbjct: 178 VGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRT 237

Query: 392 VIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDL 451
           +I S+H P Y IF +   + L+++GR MF G  ++ L YF S  Y C A+ NP+D++LD+
Sbjct: 238 IIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDI 297

Query: 452 VTLD 455
           +  D
Sbjct: 298 INGD 301



 Score = 32.7 bits (71), Expect = 5.4
 Identities = 14/82 (17%), Positives = 38/82 (46%)

Query: 637 DAFYIYLGCMVLFFINIQMVCRATIFLVPMEKTASVIAGVCLLLGTLVNGVMIQQADLPY 696
           DAF++ +  +++   +   +  A      +   A+++  +C +   + +G+++    +  
Sbjct: 504 DAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIAS 563

Query: 697 YVKWLQYVSPSRWTIPEILRRE 718
           ++ WLQY S  R+    +   E
Sbjct: 564 WLSWLQYFSIPRYGFTALQHNE 585


>AB056867-1|BAB39212.1|  655|Homo sapiens Breast Cancer Resistance
           Protein protein.
          Length = 655

 Score =  144 bits (348), Expect = 1e-33
 Identities = 84/244 (34%), Positives = 137/244 (56%), Gaps = 12/244 (4%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK--LSGDIVINGQPVASSTLRKV 276
           ++S ++  +K G + A+L       + LLDVLA  +    LSGD++ING P   +  +  
Sbjct: 63  ILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAP-RPANFKCN 120

Query: 277 VAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTN 336
             YV  D  +  T++V   L+F AALR      +H K    +RIN +I+ELGL++V D+ 
Sbjct: 121 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEK---NERINRVIQELGLDKVADSK 177

Query: 337 VGR-----LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRV 391
           VG      ++  E +R ++  +L+ D +IL LD+PT  +D      ++  L+  +  GR 
Sbjct: 178 VGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRT 237

Query: 392 VIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDL 451
           +I S+H P Y IF +   + L+++GR MF G  ++ L YF S  Y C A+ NP+D++LD+
Sbjct: 238 IIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDI 297

Query: 452 VTLD 455
           +  D
Sbjct: 298 INGD 301



 Score = 32.7 bits (71), Expect = 5.4
 Identities = 14/82 (17%), Positives = 38/82 (46%)

Query: 637 DAFYIYLGCMVLFFINIQMVCRATIFLVPMEKTASVIAGVCLLLGTLVNGVMIQQADLPY 696
           DAF++ +  +++   +   +  A      +   A+++  +C +   + +G+++    +  
Sbjct: 504 DAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIAS 563

Query: 697 YVKWLQYVSPSRWTIPEILRRE 718
           ++ WLQY S  R+    +   E
Sbjct: 564 WLSWLQYFSIPRYGFTALQHNE 585


>AB051855-1|BAB46933.1|  655|Homo sapiens ATP-binding cassette
           superfamily G (White) member 2 protein.
          Length = 655

 Score =  144 bits (348), Expect = 1e-33
 Identities = 84/244 (34%), Positives = 137/244 (56%), Gaps = 12/244 (4%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK--LSGDIVINGQPVASSTLRKV 276
           ++S ++  +K G + A+L       + LLDVLA  +    LSGD++ING P   +  +  
Sbjct: 63  ILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAP-RPANFKCN 120

Query: 277 VAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTN 336
             YV  D  +  T++V   L+F AALR      +H K    +RIN +I+ELGL++V D+ 
Sbjct: 121 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEK---NERINRVIQELGLDKVADSK 177

Query: 337 VGR-----LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRV 391
           VG      ++  E +R ++  +L+ D +IL LD+PT  +D      ++  L+  +  GR 
Sbjct: 178 VGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRT 237

Query: 392 VIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDL 451
           +I S+H P Y IF +   + L+++GR MF G  ++ L YF S  Y C A+ NP+D++LD+
Sbjct: 238 IIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDI 297

Query: 452 VTLD 455
           +  D
Sbjct: 298 INGD 301



 Score = 32.7 bits (71), Expect = 5.4
 Identities = 14/82 (17%), Positives = 38/82 (46%)

Query: 637 DAFYIYLGCMVLFFINIQMVCRATIFLVPMEKTASVIAGVCLLLGTLVNGVMIQQADLPY 696
           DAF++ +  +++   +   +  A      +   A+++  +C +   + +G+++    +  
Sbjct: 504 DAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIAS 563

Query: 697 YVKWLQYVSPSRWTIPEILRRE 718
           ++ WLQY S  R+    +   E
Sbjct: 564 WLSWLQYFSIPRYGFTALQHNE 585


>AF320293-1|AAG40003.1|  651|Homo sapiens ABCG5 protein.
          Length = 651

 Score =  132 bits (320), Expect = 4e-30
 Identities = 83/323 (25%), Positives = 156/323 (48%), Gaps = 9/323 (2%)

Query: 153 SYLLPSSHLGGRMSKAGSHMSVAHSRKHSTLRPGDQLDGYAHSAYIYPNYYVNSLEITSP 212
           S L P   +G ++++ GS  S+  +       P     G  H++Y   +      +ITS 
Sbjct: 5   SSLTPGGSMGLQVNR-GSQSSLEGA---PATAPEPHSLGILHASYSVSHRVRPWWDITSC 60

Query: 213 ENKSTL-VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLS---GDIVINGQPV 268
             + T  ++  +S  V+ G+I+ +L ++    T LLD ++G   +     G++ +NG+ +
Sbjct: 61  RQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRAL 120

Query: 269 ASSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPR-NTHSHVKMGDRDRINLLIEEL 327
                +   +YV     L  +++V  TL + A L   R N  S  K  +     L +  +
Sbjct: 121 RREQFQDCFSYVLQSDTLLSSLTVRETLHYTALLAIRRGNPGSFQKKVEAVMAELSLSHV 180

Query: 328 GLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWAS 387
               + + ++G ++  E RR+++A QLL D  +++ D+PT  +D      +V  L   A 
Sbjct: 181 ADRLIGNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELAR 240

Query: 388 TGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDY 447
             R+V++++H P  E+F +  K+ ++S G  +F G   +ML +F+   YPCP   NP D+
Sbjct: 241 RNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLDFFNDCGYPCPEHSNPFDF 300

Query: 448 YLDLVTLDXXXXXXXXXXXGRIE 470
           Y+DL ++D            R++
Sbjct: 301 YMDLTSVDTQSKEREIETSKRVQ 323


>AF312715-1|AAG53099.1|  651|Homo sapiens sterolin protein.
          Length = 651

 Score =  132 bits (320), Expect = 4e-30
 Identities = 83/323 (25%), Positives = 156/323 (48%), Gaps = 9/323 (2%)

Query: 153 SYLLPSSHLGGRMSKAGSHMSVAHSRKHSTLRPGDQLDGYAHSAYIYPNYYVNSLEITSP 212
           S L P   +G ++++ GS  S+  +       P     G  H++Y   +      +ITS 
Sbjct: 5   SSLTPGGSMGLQVNR-GSQSSLEGA---PATAPEPHSLGILHASYSVSHRVRPWWDITSC 60

Query: 213 ENKSTL-VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLS---GDIVINGQPV 268
             + T  ++  +S  V+ G+I+ +L ++    T LLD ++G   +     G++ +NG+ +
Sbjct: 61  RQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRAL 120

Query: 269 ASSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPR-NTHSHVKMGDRDRINLLIEEL 327
                +   +YV     L  +++V  TL + A L   R N  S  K  +     L +  +
Sbjct: 121 RREQFQDCFSYVLQSDTLLSSLTVRETLHYTALLAIRRGNPGSFQKKVEAVMAELSLSHV 180

Query: 328 GLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWAS 387
               + + ++G ++  E RR+++A QLL D  +++ D+PT  +D      +V  L   A 
Sbjct: 181 ADRLIGNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELAR 240

Query: 388 TGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDY 447
             R+V++++H P  E+F +  K+ ++S G  +F G   +ML +F+   YPCP   NP D+
Sbjct: 241 RNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLDFFNDCGYPCPEHSNPFDF 300

Query: 448 YLDLVTLDXXXXXXXXXXXGRIE 470
           Y+DL ++D            R++
Sbjct: 301 YMDLTSVDTQSKEREIETSKRVQ 323


>AC108476-1|AAY24010.1|  549|Homo sapiens unknown protein.
          Length = 549

 Score =  132 bits (320), Expect = 4e-30
 Identities = 83/323 (25%), Positives = 156/323 (48%), Gaps = 9/323 (2%)

Query: 153 SYLLPSSHLGGRMSKAGSHMSVAHSRKHSTLRPGDQLDGYAHSAYIYPNYYVNSLEITSP 212
           S L P   +G ++++ GS  S+  +       P     G  H++Y   +      +ITS 
Sbjct: 5   SSLTPGGSMGLQVNR-GSQSSLEGA---PATAPEPHSLGILHASYSVSHRVRPWWDITSC 60

Query: 213 ENKSTL-VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLS---GDIVINGQPV 268
             + T  ++  +S  V+ G+I+ +L ++    T LLD ++G   +     G++ +NG+ +
Sbjct: 61  RQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRAL 120

Query: 269 ASSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPR-NTHSHVKMGDRDRINLLIEEL 327
                +   +YV     L  +++V  TL + A L   R N  S  K  +     L +  +
Sbjct: 121 RREQFQDCFSYVLQSDTLLSSLTVRETLHYTALLAIRRGNPGSFQKKVEAVMAELSLSHV 180

Query: 328 GLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWAS 387
               + + ++G ++  E RR+++A QLL D  +++ D+PT  +D      +V  L   A 
Sbjct: 181 ADRLIGNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELAR 240

Query: 388 TGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDY 447
             R+V++++H P  E+F +  K+ ++S G  +F G   +ML +F+   YPCP   NP D+
Sbjct: 241 RNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLDFFNDCGYPCPEHSNPFDF 300

Query: 448 YLDLVTLDXXXXXXXXXXXGRIE 470
           Y+DL ++D            R++
Sbjct: 301 YMDLTSVDTQSKEREIETSKRVQ 323


>AY288307-1|AAP31310.1|  541|Homo sapiens ATP-binding cassette
           sub-family G member 2 protein.
          Length = 541

 Score =  126 bits (304), Expect = 3e-28
 Identities = 65/182 (35%), Positives = 105/182 (57%), Gaps = 8/182 (4%)

Query: 279 YVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVG 338
           YV  D  +  T++V   L+F AALR      +H K    +RIN +I+ELGL++V D+ VG
Sbjct: 9   YVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEK---NERINRVIQELGLDKVADSKVG 65

Query: 339 R-----LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVI 393
                 ++  E +R ++  +L+ D +IL LD+PT  +D      ++  L+  +  GR +I
Sbjct: 66  TQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTII 125

Query: 394 MSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
            S+H P Y IF +   + L+++GR MF G  ++ L YF S  Y C A+ NP+D++LD++ 
Sbjct: 126 FSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIIN 185

Query: 454 LD 455
            D
Sbjct: 186 GD 187



 Score = 32.7 bits (71), Expect = 5.4
 Identities = 14/82 (17%), Positives = 38/82 (46%)

Query: 637 DAFYIYLGCMVLFFINIQMVCRATIFLVPMEKTASVIAGVCLLLGTLVNGVMIQQADLPY 696
           DAF++ +  +++   +   +  A      +   A+++  +C +   + +G+++    +  
Sbjct: 390 DAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIAS 449

Query: 697 YVKWLQYVSPSRWTIPEILRRE 718
           ++ WLQY S  R+    +   E
Sbjct: 450 WLSWLQYFSIPRYGFTALQHNE 471


>X91249-1|CAA62631.1|  674|Homo sapiens white protein.
          Length = 674

 Score =  122 bits (293), Expect = 7e-27
 Identities = 60/236 (25%), Positives = 127/236 (53%), Gaps = 6/236 (2%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVV 277
           ++ G+S +   GE++A++  +    + L+++LAG R+  + G ++ING P      RKV 
Sbjct: 96  LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 155

Query: 278 AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
            Y+  D  L P ++V+  +   A L+           G R+ +  ++  LGL    +T  
Sbjct: 156 CYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDE-----GRREMVKEILTALGLLSCANTRT 210

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
           G L+  + +RL +A +L+ +  ++  D+PT  +D    F +V  ++  A  GR +I ++H
Sbjct: 211 GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 270

Query: 398 PPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
            P+ ++F +  ++ ++S G+ ++ G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 271 QPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVAS 326


>U34919-1|AAC51098.1|  638|Homo sapiens white homolog protein.
          Length = 638

 Score =  122 bits (293), Expect = 7e-27
 Identities = 60/236 (25%), Positives = 127/236 (53%), Gaps = 6/236 (2%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVV 277
           ++ G+S +   GE++A++  +    + L+++LAG R+  + G ++ING P      RKV 
Sbjct: 60  LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 119

Query: 278 AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
            Y+  D  L P ++V+  +   A L+           G R+ +  ++  LGL    +T  
Sbjct: 120 CYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDE-----GRREMVKEILTALGLLSCANTRT 174

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
           G L+  + +RL +A +L+ +  ++  D+PT  +D    F +V  ++  A  GR +I ++H
Sbjct: 175 GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 234

Query: 398 PPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
            P+ ++F +  ++ ++S G+ ++ G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 235 QPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVAS 290


>BC029158-1|AAH29158.2|  666|Homo sapiens ATP-binding cassette,
           sub-family G (WHITE), member 1 protein.
          Length = 666

 Score =  122 bits (293), Expect = 7e-27
 Identities = 60/236 (25%), Positives = 127/236 (53%), Gaps = 6/236 (2%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVV 277
           ++ G+S +   GE++A++  +    + L+++LAG R+  + G ++ING P      RKV 
Sbjct: 100 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 159

Query: 278 AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
            Y+  D  L P ++V+  +   A L+           G R+ +  ++  LGL    +T  
Sbjct: 160 CYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDE-----GRREMVKEILTALGLLSCANTRT 214

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
           G L+  + +RL +A +L+ +  ++  D+PT  +D    F +V  ++  A  GR +I ++H
Sbjct: 215 GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 274

Query: 398 PPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
            P+ ++F +  ++ ++S G+ ++ G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 275 QPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVAS 330


>AY048757-1|AAL06598.1|  785|Homo sapiens ATP-binding cassette
           transporter G1 protein.
          Length = 785

 Score =  122 bits (293), Expect = 7e-27
 Identities = 60/236 (25%), Positives = 127/236 (53%), Gaps = 6/236 (2%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVV 277
           ++ G+S +   GE++A++  +    + L+++LAG R+  + G ++ING P      RKV 
Sbjct: 207 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 266

Query: 278 AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
            Y+  D  L P ++V+  +   A L+           G R+ +  ++  LGL    +T  
Sbjct: 267 CYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDE-----GRREMVKEILTALGLLSCANTRT 321

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
           G L+  + +RL +A +L+ +  ++  D+PT  +D    F +V  ++  A  GR +I ++H
Sbjct: 322 GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 381

Query: 398 PPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
            P+ ++F +  ++ ++S G+ ++ G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 382 QPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVAS 437


>AP001746-1|BAA95530.1|  674|Homo sapiens white protein homolog
           (ATP-binding cassette transporter 8) protein.
          Length = 674

 Score =  122 bits (293), Expect = 7e-27
 Identities = 60/236 (25%), Positives = 127/236 (53%), Gaps = 6/236 (2%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVV 277
           ++ G+S +   GE++A++  +    + L+++LAG R+  + G ++ING P      RKV 
Sbjct: 96  LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 155

Query: 278 AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
            Y+  D  L P ++V+  +   A L+           G R+ +  ++  LGL    +T  
Sbjct: 156 CYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDE-----GRREMVKEILTALGLLSCANTRT 210

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
           G L+  + +RL +A +L+ +  ++  D+PT  +D    F +V  ++  A  GR +I ++H
Sbjct: 211 GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 270

Query: 398 PPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
            P+ ++F +  ++ ++S G+ ++ G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 271 QPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVAS 326


>AJ289137-1|CAC00730.1|  674|Homo sapiens ATP-binding cassette
           transporter, sub-family G member 1 protein.
          Length = 674

 Score =  122 bits (293), Expect = 7e-27
 Identities = 60/236 (25%), Positives = 127/236 (53%), Gaps = 6/236 (2%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVV 277
           ++ G+S +   GE++A++  +    + L+++LAG R+  + G ++ING P      RKV 
Sbjct: 96  LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 155

Query: 278 AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
            Y+  D  L P ++V+  +   A L+           G R+ +  ++  LGL    +T  
Sbjct: 156 CYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDE-----GRREMVKEILTALGLLSCANTRT 210

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
           G L+  + +RL +A +L+ +  ++  D+PT  +D    F +V  ++  A  GR +I ++H
Sbjct: 211 GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 270

Query: 398 PPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
            P+ ++F +  ++ ++S G+ ++ G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 271 QPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVAS 326


>AF323664-1|AAK28842.1|  677|Homo sapiens ATP-binding cassette
           transporter G1 variant V protein.
          Length = 677

 Score =  122 bits (293), Expect = 7e-27
 Identities = 60/236 (25%), Positives = 127/236 (53%), Gaps = 6/236 (2%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVV 277
           ++ G+S +   GE++A++  +    + L+++LAG R+  + G ++ING P      RKV 
Sbjct: 111 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 170

Query: 278 AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
            Y+  D  L P ++V+  +   A L+           G R+ +  ++  LGL    +T  
Sbjct: 171 CYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDE-----GRREMVKEILTALGLLSCANTRT 225

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
           G L+  + +RL +A +L+ +  ++  D+PT  +D    F +V  ++  A  GR +I ++H
Sbjct: 226 GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 285

Query: 398 PPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
            P+ ++F +  ++ ++S G+ ++ G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 286 QPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVAS 341


>AF323663-1|AAK28841.1|  662|Homo sapiens ATP-binding cassette
           transporter G1 variant IV protein.
          Length = 662

 Score =  122 bits (293), Expect = 7e-27
 Identities = 60/236 (25%), Positives = 127/236 (53%), Gaps = 6/236 (2%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVV 277
           ++ G+S +   GE++A++  +    + L+++LAG R+  + G ++ING P      RKV 
Sbjct: 96  LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 155

Query: 278 AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
            Y+  D  L P ++V+  +   A L+           G R+ +  ++  LGL    +T  
Sbjct: 156 CYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDE-----GRREMVKEILTALGLLSCANTRT 210

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
           G L+  + +RL +A +L+ +  ++  D+PT  +D    F +V  ++  A  GR +I ++H
Sbjct: 211 GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 270

Query: 398 PPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
            P+ ++F +  ++ ++S G+ ++ G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 271 QPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVAS 326


>AF323662-1|AAK28840.1|  663|Homo sapiens ATP-binding cassette
           transporter G1 variant III protein.
          Length = 663

 Score =  122 bits (293), Expect = 7e-27
 Identities = 60/236 (25%), Positives = 127/236 (53%), Gaps = 6/236 (2%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVV 277
           ++ G+S +   GE++A++  +    + L+++LAG R+  + G ++ING P      RKV 
Sbjct: 97  LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 156

Query: 278 AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
            Y+  D  L P ++V+  +   A L+           G R+ +  ++  LGL    +T  
Sbjct: 157 CYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDE-----GRREMVKEILTALGLLSCANTRT 211

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
           G L+  + +RL +A +L+ +  ++  D+PT  +D    F +V  ++  A  GR +I ++H
Sbjct: 212 GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 271

Query: 398 PPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
            P+ ++F +  ++ ++S G+ ++ G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 272 QPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVAS 327


>AF323661-1|AAK28839.1|  644|Homo sapiens ATP-binding cassette
           transporter G1 variant II protein.
          Length = 644

 Score =  122 bits (293), Expect = 7e-27
 Identities = 60/236 (25%), Positives = 127/236 (53%), Gaps = 6/236 (2%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVV 277
           ++ G+S +   GE++A++  +    + L+++LAG R+  + G ++ING P      RKV 
Sbjct: 78  LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 137

Query: 278 AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
            Y+  D  L P ++V+  +   A L+           G R+ +  ++  LGL    +T  
Sbjct: 138 CYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDE-----GRREMVKEILTALGLLSCANTRT 192

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
           G L+  + +RL +A +L+ +  ++  D+PT  +D    F +V  ++  A  GR +I ++H
Sbjct: 193 GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 252

Query: 398 PPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
            P+ ++F +  ++ ++S G+ ++ G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 253 QPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVAS 308


>AF323660-1|AAK28838.1|  668|Homo sapiens ATP-binding cassette
           transporter G1 variant I protein.
          Length = 668

 Score =  122 bits (293), Expect = 7e-27
 Identities = 60/236 (25%), Positives = 127/236 (53%), Gaps = 6/236 (2%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVV 277
           ++ G+S +   GE++A++  +    + L+++LAG R+  + G ++ING P      RKV 
Sbjct: 102 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 161

Query: 278 AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
            Y+  D  L P ++V+  +   A L+           G R+ +  ++  LGL    +T  
Sbjct: 162 CYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDE-----GRREMVKEILTALGLLSCANTRT 216

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
           G L+  + +RL +A +L+ +  ++  D+PT  +D    F +V  ++  A  GR +I ++H
Sbjct: 217 GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 276

Query: 398 PPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
            P+ ++F +  ++ ++S G+ ++ G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 277 QPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVAS 332


>AF323658-5|AAK28834.1|  644|Homo sapiens ATP-binding cassette
           transporter G1 variant II protein.
          Length = 644

 Score =  122 bits (293), Expect = 7e-27
 Identities = 60/236 (25%), Positives = 127/236 (53%), Gaps = 6/236 (2%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVV 277
           ++ G+S +   GE++A++  +    + L+++LAG R+  + G ++ING P      RKV 
Sbjct: 78  LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 137

Query: 278 AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
            Y+  D  L P ++V+  +   A L+           G R+ +  ++  LGL    +T  
Sbjct: 138 CYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDE-----GRREMVKEILTALGLLSCANTRT 192

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
           G L+  + +RL +A +L+ +  ++  D+PT  +D    F +V  ++  A  GR +I ++H
Sbjct: 193 GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 252

Query: 398 PPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
            P+ ++F +  ++ ++S G+ ++ G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 253 QPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVAS 308


>AF323658-4|AAK28836.1|  677|Homo sapiens ATP-binding cassette
           transporter G1 variant V protein.
          Length = 677

 Score =  122 bits (293), Expect = 7e-27
 Identities = 60/236 (25%), Positives = 127/236 (53%), Gaps = 6/236 (2%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVV 277
           ++ G+S +   GE++A++  +    + L+++LAG R+  + G ++ING P      RKV 
Sbjct: 111 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 170

Query: 278 AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
            Y+  D  L P ++V+  +   A L+           G R+ +  ++  LGL    +T  
Sbjct: 171 CYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDE-----GRREMVKEILTALGLLSCANTRT 225

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
           G L+  + +RL +A +L+ +  ++  D+PT  +D    F +V  ++  A  GR +I ++H
Sbjct: 226 GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 285

Query: 398 PPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
            P+ ++F +  ++ ++S G+ ++ G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 286 QPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVAS 341


>AF323658-3|AAK28837.1|  662|Homo sapiens ATP-binding cassette
           transporter G1 variant IV protein.
          Length = 662

 Score =  122 bits (293), Expect = 7e-27
 Identities = 60/236 (25%), Positives = 127/236 (53%), Gaps = 6/236 (2%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVV 277
           ++ G+S +   GE++A++  +    + L+++LAG R+  + G ++ING P      RKV 
Sbjct: 96  LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 155

Query: 278 AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
            Y+  D  L P ++V+  +   A L+           G R+ +  ++  LGL    +T  
Sbjct: 156 CYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDE-----GRREMVKEILTALGLLSCANTRT 210

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
           G L+  + +RL +A +L+ +  ++  D+PT  +D    F +V  ++  A  GR +I ++H
Sbjct: 211 GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 270

Query: 398 PPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
            P+ ++F +  ++ ++S G+ ++ G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 271 QPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVAS 326


>AF323658-2|AAK28835.1|  663|Homo sapiens ATP-binding cassette
           transporter G1 variant III protein.
          Length = 663

 Score =  122 bits (293), Expect = 7e-27
 Identities = 60/236 (25%), Positives = 127/236 (53%), Gaps = 6/236 (2%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVV 277
           ++ G+S +   GE++A++  +    + L+++LAG R+  + G ++ING P      RKV 
Sbjct: 97  LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 156

Query: 278 AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
            Y+  D  L P ++V+  +   A L+           G R+ +  ++  LGL    +T  
Sbjct: 157 CYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDE-----GRREMVKEILTALGLLSCANTRT 211

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
           G L+  + +RL +A +L+ +  ++  D+PT  +D    F +V  ++  A  GR +I ++H
Sbjct: 212 GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 271

Query: 398 PPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
            P+ ++F +  ++ ++S G+ ++ G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 272 QPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVAS 327


>AF323658-1|AAK28833.1|  668|Homo sapiens ATP-binding cassette
           transporter G1 variant I protein.
          Length = 668

 Score =  122 bits (293), Expect = 7e-27
 Identities = 60/236 (25%), Positives = 127/236 (53%), Gaps = 6/236 (2%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVV 277
           ++ G+S +   GE++A++  +    + L+++LAG R+  + G ++ING P      RKV 
Sbjct: 102 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 161

Query: 278 AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
            Y+  D  L P ++V+  +   A L+           G R+ +  ++  LGL    +T  
Sbjct: 162 CYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDE-----GRREMVKEILTALGLLSCANTRT 216

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
           G L+  + +RL +A +L+ +  ++  D+PT  +D    F +V  ++  A  GR +I ++H
Sbjct: 217 GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 276

Query: 398 PPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
            P+ ++F +  ++ ++S G+ ++ G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 277 QPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVAS 332


>AB038161-1|BAB13728.2|  674|Homo sapiens ABC transporter protein.
          Length = 674

 Score =  122 bits (293), Expect = 7e-27
 Identities = 60/236 (25%), Positives = 127/236 (53%), Gaps = 6/236 (2%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVV 277
           ++ G+S +   GE++A++  +    + L+++LAG R+  + G ++ING P      RKV 
Sbjct: 96  LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 155

Query: 278 AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
            Y+  D  L P ++V+  +   A L+           G R+ +  ++  LGL    +T  
Sbjct: 156 CYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDE-----GRREMVKEILTALGLLSCANTRT 210

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
           G L+  + +RL +A +L+ +  ++  D+PT  +D    F +V  ++  A  GR +I ++H
Sbjct: 211 GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 270

Query: 398 PPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
            P+ ++F +  ++ ++S G+ ++ G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 271 QPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVAS 326


>BC041091-1|AAH41091.1|  646|Homo sapiens ATP-binding cassette,
           sub-family G (WHITE), member 4 protein.
          Length = 646

 Score =  116 bits (280), Expect = 3e-25
 Identities = 57/224 (25%), Positives = 119/224 (53%), Gaps = 6/224 (2%)

Query: 231 EILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVVAYVRNDTALCPT 289
           E++ ++  +    +  +++LAG R+  + G I++NG+P    T RK+  Y+  D  L P 
Sbjct: 96  ELIGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGRPRELRTFRKMSCYIMQDDMLLPH 155

Query: 290 MSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGRLTRSEIRRLN 349
           ++V   +   A L+        VK   ++ +  ++  LGL     T    L+  + +RL 
Sbjct: 156 LTVLEAMMVSANLKLSEK--QEVK---KELVTEILTALGLMSCSHTRTALLSGGQRKRLA 210

Query: 350 VACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAMLTK 409
           +A +L+ +  ++  D+PT  +D    F +V  +++ A  GR +I ++H P+ ++F M  K
Sbjct: 211 IALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDK 270

Query: 410 VVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
           + ++S G+ +F G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 271 LYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFIIEVAS 314


>AJ308237-1|CAC87131.1|  646|Homo sapiens ABC transporter protein.
          Length = 646

 Score =  116 bits (280), Expect = 3e-25
 Identities = 57/224 (25%), Positives = 119/224 (53%), Gaps = 6/224 (2%)

Query: 231 EILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVVAYVRNDTALCPT 289
           E++ ++  +    +  +++LAG R+  + G I++NG+P    T RK+  Y+  D  L P 
Sbjct: 96  ELIGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGRPRELRTFRKMSCYIMQDDMLLPH 155

Query: 290 MSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGRLTRSEIRRLN 349
           ++V   +   A L+        VK   ++ +  ++  LGL     T    L+  + +RL 
Sbjct: 156 LTVLEAMMVSANLKLSEK--QEVK---KELVTEILTALGLMSCSHTRTALLSGGQRKRLA 210

Query: 350 VACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAMLTK 409
           +A +L+ +  ++  D+PT  +D    F +V  +++ A  GR +I ++H P+ ++F M  K
Sbjct: 211 IALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDK 270

Query: 410 VVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
           + ++S G+ +F G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 271 LYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFIIEVAS 314


>AJ300465-1|CAC17140.1|  627|Homo sapiens putative white family
           ATP-binding cassette transporter  protein.
          Length = 627

 Score =  116 bits (280), Expect = 3e-25
 Identities = 57/224 (25%), Positives = 119/224 (53%), Gaps = 6/224 (2%)

Query: 231 EILAVLATAQHEATGLLDVLAGVRKK-LSGDIVINGQPVASSTLRKVVAYVRNDTALCPT 289
           E++ ++  +    +  +++LAG R+  + G I++NG+P    T RK+  Y+  D  L P 
Sbjct: 77  ELIGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGRPRELRTFRKMSCYIMQDDMLLPH 136

Query: 290 MSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGRLTRSEIRRLN 349
           ++V   +   A L+        VK   ++ +  ++  LGL     T    L+  + +RL 
Sbjct: 137 LTVLEAMMVSANLKLSEK--QEVK---KELVTEILTALGLMSCSHTRTALLSGGQRKRLA 191

Query: 350 VACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAMLTK 409
           +A +L+ +  ++  D+PT  +D    F +V  +++ A  GR +I ++H P+ ++F M  K
Sbjct: 192 IALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDK 251

Query: 410 VVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVT 453
           + ++S G+ +F G   +++PY   +   CP + NP+D+ +++ +
Sbjct: 252 LYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFIIEVAS 295


>AK002040-1|BAA92050.1|  456|Homo sapiens protein ( Homo sapiens
           cDNA FLJ11178 fis, clone PLACE1007409, weakly similar to
           WHITE PROTEIN. ).
          Length = 456

 Score = 88.2 bits (209), Expect = 1e-16
 Identities = 38/103 (36%), Positives = 62/103 (60%)

Query: 353 QLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAMLTKVVL 412
           +L+ D +IL LD+PT  +D      ++  L+  +  GR +I S+H P Y IF +   + L
Sbjct: 2   ELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTL 61

Query: 413 ISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSDYYLDLVTLD 455
           +++GR MF G  ++ L YF S  Y C A+ NP+D++LD++  D
Sbjct: 62  LASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGD 104



 Score = 32.7 bits (71), Expect = 5.4
 Identities = 14/82 (17%), Positives = 38/82 (46%)

Query: 637 DAFYIYLGCMVLFFINIQMVCRATIFLVPMEKTASVIAGVCLLLGTLVNGVMIQQADLPY 696
           DAF++ +  +++   +   +  A      +   A+++  +C +   + +G+++    +  
Sbjct: 305 DAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIAS 364

Query: 697 YVKWLQYVSPSRWTIPEILRRE 718
           ++ WLQY S  R+    +   E
Sbjct: 365 WLSWLQYFSIPRYGFTALQHNE 386


>AF356348-1|AAL35305.1|  103|Homo sapiens breast cancer resistance
           protein protein.
          Length = 103

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 31/90 (34%), Positives = 52/90 (57%)

Query: 344 EIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEI 403
           E +R ++  +L+ D +IL LD+PT  +D      ++  L+  +  GR +I S+H P Y I
Sbjct: 13  ERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYPI 72

Query: 404 FAMLTKVVLISAGRTMFSGYRRDMLPYFSS 433
           F +   + L+++GR MF G  ++ L YF S
Sbjct: 73  FKLFDSLTLLASGRLMFHGPAQEALGYFES 102


>AF000148-1|AAC23915.1| 2273|Homo sapiens ATP-binding cassette
            transporter protein.
          Length = 2273

 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 53/220 (24%), Positives = 99/220 (45%), Gaps = 12/220 (5%)

Query: 205  NSLEITSPENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVIN 264
            N ++I  P  +    V  L+      +I A L       T  L +L G+    SG +++ 
Sbjct: 933  NLVKIFEPSGRPA--VDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVG 990

Query: 265  GQPVASS--TLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINL 322
            G+ + +S   +R+ +        L   ++V   + F+A L+      + ++M        
Sbjct: 991  GRDIETSLDAVRQSLGMCPQHNILFHHLTVAEHMLFYAQLKGKSQEEAQLEM------EA 1044

Query: 323  LIEELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYL 382
            ++E+ GL   R+     L+    R+L+VA   + D  ++ILD+PT  +D +    + + L
Sbjct: 1045 MLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVILDEPTSGVDPYSRRSIWDLL 1104

Query: 383  RNWASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSG 422
              + S GR +IMS H    E   +  ++ +I+ GR   SG
Sbjct: 1105 LKYRS-GRTIIMSTHHMD-EADLLGDRIAIIAQGRLYCSG 1142



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 53/234 (22%), Positives = 94/234 (40%), Gaps = 11/234 (4%)

Query: 216  STLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS--STL 273
            S+  V  L   V+ GE   +L       T    +L G     SGD  + G+ + +  S +
Sbjct: 1951 SSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDNTVTSGDATVAGKSILTNISEV 2010

Query: 274  RKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRI-NLLIEELGLEQV 332
             + + Y     A+   ++    L  +A LR        V   + +++ N  I+ LGL   
Sbjct: 2011 HQNMGYCPQFDAIDELLTGREHLYLYARLRG-------VPAEEIEKVANWSIKSLGLTVY 2063

Query: 333  RDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
             D   G  +    R+L+ A  L+    +++LD+PT  MD      L   + +    GR V
Sbjct: 2064 ADCLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV 2123

Query: 393  IMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSD 446
            +++ H    E  A+ T++ ++  G     G  + +   F          K+P D
Sbjct: 2124 VLTSH-SMEECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKD 2176


>Y15635-1|CAA75729.1| 2273|Homo sapiens ABCR protein.
          Length = 2273

 Score = 59.7 bits (138), Expect = 4e-08
 Identities = 48/194 (24%), Positives = 90/194 (46%), Gaps = 10/194 (5%)

Query: 231  EILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASS--TLRKVVAYVRNDTALCP 288
            +I A L       T  L +L G+    SG +++ G+ + +S   +R+ +        L  
Sbjct: 957  QITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQHNILFH 1016

Query: 289  TMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGRLTRSEIRRL 348
             ++V   + F+A L+      + ++M        ++E+ GL   R+     L+    R+L
Sbjct: 1017 HLTVAEHMLFYAQLKGKSQEEAQLEM------EAMLEDTGLHHKRNEEAQDLSGGMQRKL 1070

Query: 349  NVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAMLT 408
            +VA   + D  ++ILD+PT  +D +    + + L  + S GR +IMS H    E   +  
Sbjct: 1071 SVAIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKYRS-GRTIIMSTHHMD-EADLLGD 1128

Query: 409  KVVLISAGRTMFSG 422
            ++ +I+ GR   SG
Sbjct: 1129 RIAIIAQGRLYCSG 1142



 Score = 43.6 bits (98), Expect = 0.003
 Identities = 53/234 (22%), Positives = 94/234 (40%), Gaps = 11/234 (4%)

Query: 216  STLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS--STL 273
            S+  V  L   V+ GE   +L       T    +L G     SGD  + G+ + +  S +
Sbjct: 1951 SSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEV 2010

Query: 274  RKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRI-NLLIEELGLEQV 332
             + + Y     A+   ++    L  +A LR        V   + +++ N  I+ LGL   
Sbjct: 2011 HQNMGYCPQFDAIDELLTGREHLYLYARLRG-------VPAEEIEKVANWSIKSLGLTVY 2063

Query: 333  RDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
             D   G  +    R+L+ A  L+    +++LD+PT  MD      L   + +    GR V
Sbjct: 2064 ADCLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV 2123

Query: 393  IMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSD 446
            +++ H    E  A+ T++ ++  G     G  + +   F          K+P D
Sbjct: 2124 VLTSH-SMEECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKD 2176


>AF001945-1|AAC05632.1| 2273|Homo sapiens rim ABC transporter protein.
          Length = 2273

 Score = 59.7 bits (138), Expect = 4e-08
 Identities = 48/194 (24%), Positives = 90/194 (46%), Gaps = 10/194 (5%)

Query: 231  EILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASS--TLRKVVAYVRNDTALCP 288
            +I A L       T  L +L G+    SG +++ G+ + +S   +R+ +        L  
Sbjct: 957  QITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQHNILFH 1016

Query: 289  TMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGRLTRSEIRRL 348
             ++V   + F+A L+      + ++M        ++E+ GL   R+     L+    R+L
Sbjct: 1017 HLTVAEHMLFYAQLKGKSQEEAQLEM------EAMLEDTGLHHKRNEEAQDLSGGMQRKL 1070

Query: 349  NVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAMLT 408
            +VA   + D  ++ILD+PT  +D +    + + L  + S GR +IMS H    E   +  
Sbjct: 1071 SVAIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKYRS-GRTIIMSTHHMD-EADLLGD 1128

Query: 409  KVVLISAGRTMFSG 422
            ++ +I+ GR   SG
Sbjct: 1129 RIAIIAQGRLYCSG 1142



 Score = 43.6 bits (98), Expect = 0.003
 Identities = 53/234 (22%), Positives = 94/234 (40%), Gaps = 11/234 (4%)

Query: 216  STLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS--STL 273
            S+  V  L   V+ GE   +L       T    +L G     SGD  + G+ + +  S +
Sbjct: 1951 SSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEV 2010

Query: 274  RKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRI-NLLIEELGLEQV 332
             + + Y     A+   ++    L  +A LR        V   + +++ N  I+ LGL   
Sbjct: 2011 HQNMGYCPQFDAIDELLTGREHLYLYARLRG-------VPAEEIEKVANWSIKSLGLTVY 2063

Query: 333  RDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
             D   G  +    R+L+ A  L+    +++LD+PT  MD      L   + +    GR V
Sbjct: 2064 ADCLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV 2123

Query: 393  IMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSD 446
            +++ H    E  A+ T++ ++  G     G  + +   F          K+P D
Sbjct: 2124 VLTSH-SMEECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKD 2176


>AB210040-1|BAE06122.1| 2303|Homo sapiens ABCA4 variant protein
            protein.
          Length = 2303

 Score = 59.7 bits (138), Expect = 4e-08
 Identities = 48/194 (24%), Positives = 90/194 (46%), Gaps = 10/194 (5%)

Query: 231  EILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASS--TLRKVVAYVRNDTALCP 288
            +I A L       T  L +L G+    SG +++ G+ + +S   +R+ +        L  
Sbjct: 987  QITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQHNILFH 1046

Query: 289  TMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGRLTRSEIRRL 348
             ++V   + F+A L+      + ++M        ++E+ GL   R+     L+    R+L
Sbjct: 1047 HLTVAEHMLFYAQLKGKSQEEAQLEM------EAMLEDTGLHHKRNEEAQDLSGGMQRKL 1100

Query: 349  NVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAMLT 408
            +VA   + D  ++ILD+PT  +D +    + + L  + S GR +IMS H    E   +  
Sbjct: 1101 SVAIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKYRS-GRTIIMSTHHMD-EADLLGD 1158

Query: 409  KVVLISAGRTMFSG 422
            ++ +I+ GR   SG
Sbjct: 1159 RIAIIAQGRLYCSG 1172



 Score = 43.6 bits (98), Expect = 0.003
 Identities = 53/234 (22%), Positives = 94/234 (40%), Gaps = 11/234 (4%)

Query: 216  STLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS--STL 273
            S+  V  L   V+ GE   +L       T    +L G     SGD  + G+ + +  S +
Sbjct: 1981 SSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEV 2040

Query: 274  RKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRI-NLLIEELGLEQV 332
             + + Y     A+   ++    L  +A LR        V   + +++ N  I+ LGL   
Sbjct: 2041 HQNMGYCPQFDAIDELLTGREHLYLYARLRG-------VPAEEIEKVANWSIKSLGLTVY 2093

Query: 333  RDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
             D   G  +    R+L+ A  L+    +++LD+PT  MD      L   + +    GR V
Sbjct: 2094 ADCLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV 2153

Query: 393  IMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSD 446
            +++ H    E  A+ T++ ++  G     G  + +   F          K+P D
Sbjct: 2154 VLTSH-SMEECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKD 2206


>U88667-1|AAC51144.1| 2273|Homo sapiens ATP-binding cassette
            transporter protein.
          Length = 2273

 Score = 56.4 bits (130), Expect = 4e-07
 Identities = 47/194 (24%), Positives = 88/194 (45%), Gaps = 10/194 (5%)

Query: 231  EILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASS--TLRKVVAYVRNDTALCP 288
            +I A L       T  L +L G+    SG +++ G+ + +S   +R+ +        L  
Sbjct: 957  QITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQHNILFH 1016

Query: 289  TMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGRLTRSEIRRL 348
             ++V   + F+A L+      + ++M        ++E+ GL   R+     L+    R+L
Sbjct: 1017 HLTVAEHMLFYAQLKGKSQEEAQLEM------EAMLEDTGLHHKRNEEAQDLSGGMQRKL 1070

Query: 349  NVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAMLT 408
            +VA   + D  ++ILD+PT  +D +    + + L  + S GR +IM  H    E      
Sbjct: 1071 SVAIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKYRS-GRTIIMPTHHMD-EADHQGD 1128

Query: 409  KVVLISAGRTMFSG 422
            ++ +I+ GR   SG
Sbjct: 1129 RIAIIAQGRLYCSG 1142



 Score = 43.6 bits (98), Expect = 0.003
 Identities = 53/234 (22%), Positives = 94/234 (40%), Gaps = 11/234 (4%)

Query: 216  STLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS--STL 273
            S+  V  L   V+ GE   +L       T    +L G     SGD  + G+ + +  S +
Sbjct: 1951 SSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEV 2010

Query: 274  RKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRI-NLLIEELGLEQV 332
             + + Y     A+   ++    L  +A LR        V   + +++ N  I+ LGL   
Sbjct: 2011 HQNMGYCPQFDAIDELLTGREHLYLYARLRG-------VPAEEIEKVANWSIKSLGLTVY 2063

Query: 333  RDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
             D   G  +    R+L+ A  L+    +++LD+PT  MD      L   + +    GR V
Sbjct: 2064 ADCLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSIIRKGRAV 2123

Query: 393  IMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSSIDYPCPAFKNPSD 446
            +++ H    E  A+ T++ ++  G     G  + +   F          K+P D
Sbjct: 2124 VLTSH-SMEECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKD 2176


>BC125232-1|AAI25233.1| 1500|Homo sapiens ABCA6 protein protein.
          Length = 1500

 Score = 56.0 bits (129), Expect = 5e-07
 Identities = 49/206 (23%), Positives = 99/206 (48%), Gaps = 10/206 (4%)

Query: 220 VSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTLRKVVAY 279
           + GL F++  G+I A+L  +    + LL++L G+     G + I  + ++     + +  
Sbjct: 497 LKGLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTEGSVTIYNKNLSEM---QDLEE 553

Query: 280 VRNDTALCPTMSVEH---TLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTN 336
           +R  T +CP  +V+    T++ + +L   +    H+K  +++   +L+E L ++ ++D  
Sbjct: 554 IRKITGVCPQFNVQFDILTVKENLSLFA-KIKGIHLKEVEQEVQRILLE-LDMQNIQDNL 611

Query: 337 VGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSL 396
              L+  + R+L     +L D  IL+LD+PT  +D F    +   LR       V++ S 
Sbjct: 612 AKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLDPFSRDQVWSLLRE-RRADHVILFST 670

Query: 397 HPPTYEIFAMLTKVVLISAGRTMFSG 422
                E   +  + V++S GR   +G
Sbjct: 671 QSMD-EADILADRKVIMSNGRLKCAG 695



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 49/206 (23%), Positives = 97/206 (47%), Gaps = 12/206 (5%)

Query: 213  ENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST 272
            + K  +    +SF V+ GEIL +L  +    +  + +++G+ K  +G++ + G    SS 
Sbjct: 1296 KRKKKIAARNISFCVQEGEILGLLGPSGAGKSSSIRMISGITKPTAGEVELKG---CSSV 1352

Query: 273  LRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQV 332
            L   + Y   +  L P +++   L  +AA++  R      K   R  I  L+    L + 
Sbjct: 1353 LGH-LGYCPQENVLWPMLTLREHLEVYAAVKGLR------KADARLAIARLVSAFKLHEQ 1405

Query: 333  RDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWA-STGRV 391
             +  V +LT    R+L     LL +  +L+LD+P+  +D      + + ++    +T R 
Sbjct: 1406 LNVPVQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERG 1465

Query: 392  VIMSLHPPTYEIFAMLTKVVLISAGR 417
            V+++ H    E  A+  +V ++ +GR
Sbjct: 1466 VLLTTH-NLAEAEALCDRVAIMVSGR 1490


>BC125231-1|AAI25232.1| 1500|Homo sapiens ABCA6 protein protein.
          Length = 1500

 Score = 56.0 bits (129), Expect = 5e-07
 Identities = 49/206 (23%), Positives = 99/206 (48%), Gaps = 10/206 (4%)

Query: 220 VSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTLRKVVAY 279
           + GL F++  G+I A+L  +    + LL++L G+     G + I  + ++     + +  
Sbjct: 497 LKGLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTEGSVTIYNKNLSEM---QDLEE 553

Query: 280 VRNDTALCPTMSVEH---TLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTN 336
           +R  T +CP  +V+    T++ + +L   +    H+K  +++   +L+E L ++ ++D  
Sbjct: 554 IRKITGVCPQFNVQFDILTVKENLSLFA-KIKGIHLKEVEQEVQRILLE-LDMQNIQDNL 611

Query: 337 VGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSL 396
              L+  + R+L     +L D  IL+LD+PT  +D F    +   LR       V++ S 
Sbjct: 612 AKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLDPFSRDQVWSLLRE-RRADHVILFST 670

Query: 397 HPPTYEIFAMLTKVVLISAGRTMFSG 422
                E   +  + V++S GR   +G
Sbjct: 671 QSMD-EADILADRKVIMSNGRLKCAG 695



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 49/206 (23%), Positives = 97/206 (47%), Gaps = 12/206 (5%)

Query: 213  ENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST 272
            + K  +    +SF V+ GEIL +L  +    +  + +++G+ K  +G++ + G    SS 
Sbjct: 1296 KRKKKIAARNISFCVQEGEILGLLGPSGAGKSSSIRMISGITKPTAGEVELKG---CSSV 1352

Query: 273  LRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQV 332
            L   + Y   +  L P +++   L  +AA++  R      K   R  I  L+    L + 
Sbjct: 1353 LGH-LGYCPQENVLWPMLTLREHLEVYAAVKGLR------KADARLAIARLVSAFKLHEQ 1405

Query: 333  RDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWA-STGRV 391
             +  V +LT    R+L     LL +  +L+LD+P+  +D      + + ++    +T R 
Sbjct: 1406 LNVPVQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERG 1465

Query: 392  VIMSLHPPTYEIFAMLTKVVLISAGR 417
            V+++ H    E  A+  +V ++ +GR
Sbjct: 1466 VLLTTH-NLAEAEALCDRVAIMVSGR 1490


>AY028898-1|AAK30023.1| 1617|Homo sapiens ATP-binding cassette A6
           protein.
          Length = 1617

 Score = 56.0 bits (129), Expect = 5e-07
 Identities = 49/206 (23%), Positives = 99/206 (48%), Gaps = 10/206 (4%)

Query: 220 VSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTLRKVVAY 279
           + GL F++  G+I A+L  +    + LL++L G+     G + I  + ++     + +  
Sbjct: 497 LKGLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTEGSVTIYNKNLSEM---QDLEE 553

Query: 280 VRNDTALCPTMSVEH---TLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTN 336
           +R  T +CP  +V+    T++ + +L   +    H+K  +++   +L+E L ++ ++D  
Sbjct: 554 IRKITGVCPQFNVQFDILTVKENLSLFA-KIKGIHLKEVEQEVQRILLE-LDMQNIQDNL 611

Query: 337 VGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSL 396
              L+  + R+L     +L D  IL+LD+PT  +D F    +   LR       V++ S 
Sbjct: 612 AKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLDPFSRDQVWSLLRE-RRADHVILFST 670

Query: 397 HPPTYEIFAMLTKVVLISAGRTMFSG 422
                E   +  + V++S GR   +G
Sbjct: 671 QSMD-EADILADRKVIMSNGRLKCAG 695



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 49/206 (23%), Positives = 97/206 (47%), Gaps = 12/206 (5%)

Query: 213  ENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST 272
            + K  +    +SF V+ GEIL +L  +    +  + +++G+ K  +G++ + G    SS 
Sbjct: 1296 KRKKKIAARNISFCVQEGEILGLLGPSGAGKSSSIRMISGITKPTAGEVELKG---CSSV 1352

Query: 273  LRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQV 332
            L   + Y   +  L P +++   L  +AA++  R      K   R  I  L+    L + 
Sbjct: 1353 LGH-LGYCPQENVLWPMLTLREHLEVYAAVKGLR------KADARLAIARLVSAFKLHEQ 1405

Query: 333  RDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWA-STGRV 391
             +  V +LT    R+L     LL +  +L+LD+P+  +D      + + ++    +T R 
Sbjct: 1406 LNVPVQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERG 1465

Query: 392  VIMSLHPPTYEIFAMLTKVVLISAGR 417
            V+++ H    E  A+  +V ++ +GR
Sbjct: 1466 VLLTTH-NLAEAEALCDRVAIMVSGR 1490


>AF373328-1|AAM77558.1| 1617|Homo sapiens ABC transporter ABCA6
           protein.
          Length = 1617

 Score = 56.0 bits (129), Expect = 5e-07
 Identities = 49/206 (23%), Positives = 99/206 (48%), Gaps = 10/206 (4%)

Query: 220 VSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTLRKVVAY 279
           + GL F++  G+I A+L  +    + LL++L G+     G + I  + ++     + +  
Sbjct: 497 LKGLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTEGSVTIYNKNLSEM---QDLEE 553

Query: 280 VRNDTALCPTMSVEH---TLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTN 336
           +R  T +CP  +V+    T++ + +L   +    H+K  +++   +L+E L ++ ++D  
Sbjct: 554 IRKITGVCPQFNVQFDILTVKENLSLFA-KIKGIHLKEVEQEVQRILLE-LDMQNIQDNL 611

Query: 337 VGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSL 396
              L+  + R+L     +L D  IL+LD+PT  +D F    +   LR       V++ S 
Sbjct: 612 AKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLDPFSRDQVWSLLRE-RRADHVILFST 670

Query: 397 HPPTYEIFAMLTKVVLISAGRTMFSG 422
                E   +  + V++S GR   +G
Sbjct: 671 QSMD-EADILADRKVIMSNGRLKCAG 695



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 49/206 (23%), Positives = 96/206 (46%), Gaps = 12/206 (5%)

Query: 213  ENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST 272
            + K  +    +SF V+ GEIL +L       +  + +++G+ K  +G++ + G    SS 
Sbjct: 1296 KRKKKIAARNISFCVQEGEILGLLGPNGAGKSSSIRMISGITKPTAGEVELKG---CSSV 1352

Query: 273  LRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQV 332
            L   + Y   +  L P +++   L  +AA++  R      K   R  I  L+    L + 
Sbjct: 1353 LGH-LGYCPQENVLWPMLTLREHLEVYAAVKGLR------KADARLAIARLVSAFKLHEQ 1405

Query: 333  RDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWA-STGRV 391
             +  V +LT    R+L     LL +  +L+LD+P+  +D      + + ++    +T R 
Sbjct: 1406 LNVPVQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERG 1465

Query: 392  VIMSLHPPTYEIFAMLTKVVLISAGR 417
            V+++ H    E  A+  +V ++ +GR
Sbjct: 1466 VLLTTH-NLAEAEALCDRVAIMVSGR 1490


>AF373290-1|AAM77557.1| 1617|Homo sapiens ABC transporter ABCA6
           protein.
          Length = 1617

 Score = 56.0 bits (129), Expect = 5e-07
 Identities = 49/206 (23%), Positives = 99/206 (48%), Gaps = 10/206 (4%)

Query: 220 VSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTLRKVVAY 279
           + GL F++  G+I A+L  +    + LL++L G+     G + I  + ++     + +  
Sbjct: 497 LKGLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTEGSVTIYNKNLSEM---QDLEE 553

Query: 280 VRNDTALCPTMSVEH---TLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTN 336
           +R  T +CP  +V+    T++ + +L   +    H+K  +++   +L+E L ++ ++D  
Sbjct: 554 IRKITGVCPQFNVQFDILTVKENLSLFA-KIKGIHLKEVEQEVQRILLE-LDMQNIQDNL 611

Query: 337 VGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSL 396
              L+  + R+L     +L D  IL+LD+PT  +D F    +   LR       V++ S 
Sbjct: 612 AKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLDPFSRDQVWSLLRE-RRADHVILFST 670

Query: 397 HPPTYEIFAMLTKVVLISAGRTMFSG 422
                E   +  + V++S GR   +G
Sbjct: 671 QSMD-EADILADRKVIMSNGRLKCAG 695



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 49/206 (23%), Positives = 96/206 (46%), Gaps = 12/206 (5%)

Query: 213  ENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST 272
            + K  +    +SF V+ GEIL +L       +  + +++G+ K  +G++ + G    SS 
Sbjct: 1296 KRKKKIAARNISFCVQEGEILGLLGPNGAGKSSSIRMISGITKPTAGEVELKG---CSSV 1352

Query: 273  LRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQV 332
            L   + Y   +  L P +++   L  +AA++  R      K   R  I  L+    L + 
Sbjct: 1353 LGH-LGYCPQENVLWPMLTLREHLEVYAAVKGLR------KADARLAIARLVSAFKLHEQ 1405

Query: 333  RDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWA-STGRV 391
             +  V +LT    R+L     LL +  +L+LD+P+  +D      + + ++    +T R 
Sbjct: 1406 LNVPVQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERG 1465

Query: 392  VIMSLHPPTYEIFAMLTKVVLISAGR 417
            V+++ H    E  A+  +V ++ +GR
Sbjct: 1466 VLLTTH-NLAEAEALCDRVAIMVSGR 1490


>AF327705-1|AAK14335.1| 2436|Homo sapiens ABC transporter ABCA2
            protein.
          Length = 2436

 Score = 56.0 bits (129), Expect = 5e-07
 Identities = 51/203 (25%), Positives = 84/203 (41%), Gaps = 11/203 (5%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTLR--K 275
            L V  L   V+ GE   +L       T    +L G      G+  +NG  V    L+  +
Sbjct: 2069 LAVDRLCLGVRLGECFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKELLQVQQ 2128

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRI-NLLIEELGLEQVRD 334
             + Y     AL   ++    L+ +  LR        +   D  R+    +E+L L +  D
Sbjct: 2129 SLGYCPQCDALFDELTAREHLQLYTRLRG-------ISWKDEARVVKWALEKLELTKYAD 2181

Query: 335  TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
               G  +    R+L+ A  L+   A + LD+PT  MD     FL   + +   TGR V++
Sbjct: 2182 KPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDLIKTGRSVVL 2241

Query: 395  SLHPPTYEIFAMLTKVVLISAGR 417
            + H    E  A+ T++ ++  GR
Sbjct: 2242 TSH-SMEECEALCTRLAIMVNGR 2263



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 47/207 (22%), Positives = 92/207 (44%), Gaps = 10/207 (4%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST--LRK 275
            L ++ LS  +   ++++ L       T  + +L G+    SG   I G  + +    +RK
Sbjct: 1006 LALNKLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIRK 1065

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDT 335
             +        L   ++VE  L F++ L+      S  +   R  ++ +IE+L L   R +
Sbjct: 1066 NLGMCPQHNVLFDRLTVEEHLWFYSRLK------SMAQEEIRREMDKMIEDLELSNKRHS 1119

Query: 336  NVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMS 395
             V  L+    R+L+VA   +     +ILD+PT  +D +    + + +  +   GR +++S
Sbjct: 1120 LVQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKY-KPGRTILLS 1178

Query: 396  LHPPTYEIFAMLTKVVLISAGRTMFSG 422
             H    E   +  ++ +IS G+    G
Sbjct: 1179 THHMD-EADLLGDRIAIISHGKLKCCG 1204


>AY204751-1|AAP13576.1| 5058|Homo sapiens ABC A13 protein.
          Length = 5058

 Score = 55.6 bits (128), Expect = 7e-07
 Identities = 52/222 (23%), Positives = 93/222 (41%), Gaps = 10/222 (4%)

Query: 204  VNSLEITSPENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVI 263
            V  + +T        VV  LS      +I A+L T     T ++ +L G+    SG I+I
Sbjct: 3842 VTLVSVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIII 3901

Query: 264  NGQPVASSTLRKVVAYVRNDTALCPTMSV---EHTLRFHAALRKPRNTHSHVKMGDRDRI 320
            NG+      L+  ++ VR +  +CP   +     T+R H  L          K     ++
Sbjct: 3902 NGK-----NLQTDLSRVRMELGVCPQQDILLDNLTVREHLLLFASIKAPQWTKKELHQQV 3956

Query: 321  NLLIEELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVE 380
            N  ++++ L Q +      L+    R+L++    +     ++LD+PT  +D      L +
Sbjct: 3957 NQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWD 4016

Query: 381  YLRNWASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSG 422
             L  +   GR +I + H    E  A+  +V ++  GR    G
Sbjct: 4017 ILLKYRE-GRTIIFTTH-HLDEAEALSDRVAVLQHGRLRCCG 4056



 Score = 36.7 bits (81), Expect = 0.33
 Identities = 49/209 (23%), Positives = 85/209 (40%), Gaps = 15/209 (7%)

Query: 215  KSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVIN---GQPV--- 268
            ++ + V  +S  +  GE   +L       +    +L G     SG  +I    G  V   
Sbjct: 4732 QNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLS 4791

Query: 269  ASSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRK-PRNTHSHVKMGDRDRINLLIEEL 327
            ++ T   ++ Y     AL   ++    L ++ +LR  PR     V  GD      LI  L
Sbjct: 4792 SAGTAGVLIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVA-GD------LIRRL 4844

Query: 328  GLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWAS 387
             LE   D  V   +    R+L+ A  L+    IL+LD+P+  MD     +L + +     
Sbjct: 4845 HLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVR 4904

Query: 388  TGRVVIMSLHPPTYEIFAMLTKVVLISAG 416
             G   +++ H    E  A+ T++ ++  G
Sbjct: 4905 EGCAAVLTSH-SMEECEALCTRLAIMVNG 4932


>AK131360-1|BAD18512.1| 1186|Homo sapiens  mRNA.  protein.
          Length = 1186

 Score = 55.6 bits (128), Expect = 7e-07
 Identities = 52/222 (23%), Positives = 93/222 (41%), Gaps = 10/222 (4%)

Query: 204 VNSLEITSPENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVI 263
           V  + +T        VV  LS      +I A+L T     T ++ +L G+    SG I+I
Sbjct: 102 VTLVSVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIII 161

Query: 264 NGQPVASSTLRKVVAYVRNDTALCPTMSV---EHTLRFHAALRKPRNTHSHVKMGDRDRI 320
           NG+      L+  ++ VR +  +CP   +     T+R H  L          K     ++
Sbjct: 162 NGK-----NLQTDLSRVRMELGVCPQQDILLDNLTVREHLLLFASIKAPQWTKKELHQQV 216

Query: 321 NLLIEELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVE 380
           N  ++++ L Q +      L+    R+L++    +     ++LD+PT  +D      L +
Sbjct: 217 NQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWD 276

Query: 381 YLRNWASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSG 422
            L  +   GR +I + H    E  A+  +V ++  GR    G
Sbjct: 277 ILLKYRE-GRTIIFTTH-HLDEAEALSDRVAVLQHGRLRCCG 316



 Score = 36.7 bits (81), Expect = 0.33
 Identities = 49/202 (24%), Positives = 81/202 (40%), Gaps = 14/202 (6%)

Query: 215  KSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVIN---GQPV--- 268
            ++ + V  +S  +  GE   +L       +    +L G     SG  +I    G  V   
Sbjct: 992  QNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLS 1051

Query: 269  ASSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRK-PRNTHSHVKMGDRDRINLLIEEL 327
            ++ T   ++ Y     AL   ++    L ++ +LR  PR     V  GD      LI  L
Sbjct: 1052 SAGTAGVLIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVA-GD------LIRRL 1104

Query: 328  GLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWAS 387
             LE   D  V   +    R+L+ A  L+    IL+LD+P+  MD     +L + +     
Sbjct: 1105 HLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVR 1164

Query: 388  TGRVVIMSLHPPTYEIFAMLTK 409
             G   +++ H   Y+  A L K
Sbjct: 1165 EGCAAVLTSHRFWYQDDAGLIK 1186


>BC008755-1|AAH08755.1|  867|Homo sapiens ABCA2 protein protein.
          Length = 867

 Score = 55.2 bits (127), Expect = 9e-07
 Identities = 51/203 (25%), Positives = 84/203 (41%), Gaps = 11/203 (5%)

Query: 218 LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTLR--K 275
           L V  L   V+ GE   +L       T    +L G      G+  +NG  V    L+  +
Sbjct: 500 LAVDRLCLGVRPGECFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKELLQVQQ 559

Query: 276 VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRI-NLLIEELGLEQVRD 334
            + Y     AL   ++    L+ +  LR        +   D  R+    +E+L L +  D
Sbjct: 560 SLGYCPQCDALFDELTAREHLQLYTRLRG-------ISWKDEARVVKWALEKLELTKYAD 612

Query: 335 TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
              G  +    R+L+ A  L+   A + LD+PT  MD     FL   + +   TGR V++
Sbjct: 613 KPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDLIKTGRSVVL 672

Query: 395 SLHPPTYEIFAMLTKVVLISAGR 417
           + H    E  A+ T++ ++  GR
Sbjct: 673 TSH-SMEECEALCTRLAIMVNGR 694


>AL807752-22|CAI12768.1| 2435|Homo sapiens ATP-binding cassette,
            sub-family A (ABC1), membertor protein.
          Length = 2435

 Score = 55.2 bits (127), Expect = 9e-07
 Identities = 51/203 (25%), Positives = 84/203 (41%), Gaps = 11/203 (5%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTLR--K 275
            L V  L   V+ GE   +L       T    +L G      G+  +NG  V    L+  +
Sbjct: 2068 LAVDRLCLGVRPGECFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKELLQVQQ 2127

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRI-NLLIEELGLEQVRD 334
             + Y     AL   ++    L+ +  LR        +   D  R+    +E+L L +  D
Sbjct: 2128 SLGYCPQCDALFDELTAREHLQLYTRLRG-------ISWKDEARVVKWALEKLELTKYAD 2180

Query: 335  TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
               G  +    R+L+ A  L+   A + LD+PT  MD     FL   + +   TGR V++
Sbjct: 2181 KPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDLIKTGRSVVL 2240

Query: 395  SLHPPTYEIFAMLTKVVLISAGR 417
            + H    E  A+ T++ ++  GR
Sbjct: 2241 TSH-SMEECEALCTRLAIMVNGR 2262



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 47/207 (22%), Positives = 92/207 (44%), Gaps = 10/207 (4%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST--LRK 275
            L ++ LS  +   ++++ L       T  + +L G+    SG   I G  + +    +RK
Sbjct: 1005 LALNKLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIRK 1064

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDT 335
             +        L   ++VE  L F++ L+      S  +   R  ++ +IE+L L   R +
Sbjct: 1065 NLGMCPQHNVLFDRLTVEEHLWFYSRLK------SMAQEEIRREMDKMIEDLELSNKRHS 1118

Query: 336  NVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMS 395
             V  L+    R+L+VA   +     +ILD+PT  +D +    + + +  +   GR +++S
Sbjct: 1119 LVQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKY-KPGRTILLS 1177

Query: 396  LHPPTYEIFAMLTKVVLISAGRTMFSG 422
             H    E   +  ++ +IS G+    G
Sbjct: 1178 THHMD-EADLLGDRIAIISHGKLKCCG 1203


>AL807752-20|CAI12766.1|  226|Homo sapiens ATP-binding cassette,
           sub-family A (ABC1), membertor protein.
          Length = 226

 Score = 55.2 bits (127), Expect = 9e-07
 Identities = 51/203 (25%), Positives = 84/203 (41%), Gaps = 11/203 (5%)

Query: 218 LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTLR--K 275
           L V  L   V+ GE   +L       T    +L G      G+  +NG  V    L+  +
Sbjct: 22  LAVDRLCLGVRPGECFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKELLQVQQ 81

Query: 276 VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRI-NLLIEELGLEQVRD 334
            + Y     AL   ++    L+ +  LR        +   D  R+    +E+L L +  D
Sbjct: 82  SLGYCPQCDALFDELTAREHLQLYTRLRG-------ISWKDEARVVKWALEKLELTKYAD 134

Query: 335 TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
              G  +    R+L+ A  L+   A + LD+PT  MD     FL   + +   TGR V++
Sbjct: 135 KPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDLIKTGRSVVL 194

Query: 395 SLHPPTYEIFAMLTKVVLISAGR 417
           + H    E  A+ T++ ++  GR
Sbjct: 195 TSH-SMEECEALCTRLAIMVNGR 216


>AL162060-1|CAB82398.1|  373|Homo sapiens hypothetical protein
           protein.
          Length = 373

 Score = 55.2 bits (127), Expect = 9e-07
 Identities = 51/203 (25%), Positives = 84/203 (41%), Gaps = 11/203 (5%)

Query: 218 LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTLR--K 275
           L V  L   V+ GE   +L       T    +L G      G+  +NG  V    L+  +
Sbjct: 6   LAVDRLCLGVRPGECFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKELLQVQQ 65

Query: 276 VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRI-NLLIEELGLEQVRD 334
            + Y     AL   ++    L+ +  LR        +   D  R+    +E+L L +  D
Sbjct: 66  SLGYCPQCDALFDELTAREHLQLYTRLRG-------ISWKDEARVVKWALEKLELTKYAD 118

Query: 335 TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
              G  +    R+L+ A  L+   A + LD+PT  MD     FL   + +   TGR V++
Sbjct: 119 KPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDLIKTGRSVVL 178

Query: 395 SLHPPTYEIFAMLTKVVLISAGR 417
           + H    E  A+ T++ ++  GR
Sbjct: 179 TSH-SMEECEALCTRLAIMVNGR 200


>AF501281-1|AAO59914.1| 2127|Homo sapiens ATP binding cassette
            transporter A13 protein.
          Length = 2127

 Score = 55.2 bits (127), Expect = 9e-07
 Identities = 52/222 (23%), Positives = 93/222 (41%), Gaps = 10/222 (4%)

Query: 204  VNSLEITSPENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVI 263
            V  + +T        VV  LS      +I A+L T     T ++ +L G+    SG I+I
Sbjct: 910  VTLVSVTKEFEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIII 969

Query: 264  NGQPVASSTLRKVVAYVRNDTALCPTMSV---EHTLRFHAALRKPRNTHSHVKMGDRDRI 320
            NG+      L+  ++ VR +  +CP   +     T+R H  L          K     ++
Sbjct: 970  NGK-----NLQTDLSRVRMELGVCPQQDILLDNLTVREHLLLFASIKAPQWTKKELHQQV 1024

Query: 321  NLLIEELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVE 380
            N  ++++ L Q +      L+    R+L++    +     ++LD+PT  +D      L +
Sbjct: 1025 NQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWD 1084

Query: 381  YLRNWASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSG 422
             L  +   GR +I + H    E  A+  +V ++  GR    G
Sbjct: 1085 ILLKYRE-GRTIIFTTH-HLDEAEALSDRVAVLQHGRLRCCG 1124



 Score = 36.7 bits (81), Expect = 0.33
 Identities = 49/209 (23%), Positives = 85/209 (40%), Gaps = 15/209 (7%)

Query: 215  KSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVIN---GQPV--- 268
            ++ + V  +S  +  GE   +L       +    +L G     SG  +I    G  V   
Sbjct: 1801 QNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLS 1860

Query: 269  ASSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRK-PRNTHSHVKMGDRDRINLLIEEL 327
            ++ T   ++ Y     AL   ++    L ++ +LR  PR     V  GD      LI  L
Sbjct: 1861 SAGTAGVLIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVA-GD------LIRRL 1913

Query: 328  GLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWAS 387
             LE   D  V   +    R+L+ A  L+    IL+LD+P+  MD     +L + +     
Sbjct: 1914 HLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVR 1973

Query: 388  TGRVVIMSLHPPTYEIFAMLTKVVLISAG 416
             G   +++ H    E  A+ T++ ++  G
Sbjct: 1974 EGCAAVLTSH-SMEECEALCTRLAIMVNG 2001


>AF327657-1|AAK14334.1| 2436|Homo sapiens ABC transporter ABCA2
            protein.
          Length = 2436

 Score = 55.2 bits (127), Expect = 9e-07
 Identities = 51/203 (25%), Positives = 84/203 (41%), Gaps = 11/203 (5%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTLR--K 275
            L V  L   V+ GE   +L       T    +L G      G+  +NG  V    L+  +
Sbjct: 2069 LAVDRLCLGVRPGECFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKELLQVQQ 2128

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRI-NLLIEELGLEQVRD 334
             + Y     AL   ++    L+ +  LR        +   D  R+    +E+L L +  D
Sbjct: 2129 SLGYCPQCDALFDELTAREHLQLYTRLRG-------ISWKDEARVVKWALEKLELTKYAD 2181

Query: 335  TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
               G  +    R+L+ A  L+   A + LD+PT  MD     FL   + +   TGR V++
Sbjct: 2182 KPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDLIKTGRSVVL 2241

Query: 395  SLHPPTYEIFAMLTKVVLISAGR 417
            + H    E  A+ T++ ++  GR
Sbjct: 2242 TSH-SMEECEALCTRLAIMVNGR 2263



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 47/207 (22%), Positives = 92/207 (44%), Gaps = 10/207 (4%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST--LRK 275
            L ++ LS  +   ++++ L       T  + +L G+    SG   I G  + +    +RK
Sbjct: 1006 LALNKLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIRK 1065

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDT 335
             +        L   ++VE  L F++ L+      S  +   R  ++ +IE+L L   R +
Sbjct: 1066 NLGMCPQHNVLFDRLTVEEHLWFYSRLK------SMAQEEIRREMDKMIEDLELSNKRHS 1119

Query: 336  NVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMS 395
             V  L+    R+L+VA   +     +ILD+PT  +D +    + + +  +   GR +++S
Sbjct: 1120 LVQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKY-KPGRTILLS 1178

Query: 396  LHPPTYEIFAMLTKVVLISAGRTMFSG 422
             H    E   +  ++ +IS G+    G
Sbjct: 1179 THHMD-EADLLGDRIAIISHGKLKCCG 1204


>AF178941-1|AAG09372.1| 2436|Homo sapiens ATP-binding cassette
            sub-family A member 2 protein.
          Length = 2436

 Score = 55.2 bits (127), Expect = 9e-07
 Identities = 51/203 (25%), Positives = 84/203 (41%), Gaps = 11/203 (5%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTLR--K 275
            L V  L   V+ GE   +L       T    +L G      G+  +NG  V    L+  +
Sbjct: 2069 LAVDRLCLGVRPGECFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKELLQVQQ 2128

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRI-NLLIEELGLEQVRD 334
             + Y     AL   ++    L+ +  LR        +   D  R+    +E+L L +  D
Sbjct: 2129 SLGYCPQCDALFDELTAREHLQLYTRLRG-------ISWKDEARVVKWALEKLELTKYAD 2181

Query: 335  TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
               G  +    R+L+ A  L+   A + LD+PT  MD     FL   + +   TGR V++
Sbjct: 2182 KPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDLIKTGRSVVL 2241

Query: 395  SLHPPTYEIFAMLTKVVLISAGR 417
            + H    E  A+ T++ ++  GR
Sbjct: 2242 TSH-SMEECEALCTRLAIMVNGR 2263



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 47/207 (22%), Positives = 92/207 (44%), Gaps = 10/207 (4%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST--LRK 275
            L ++ LS  +   ++++ L       T  + +L G+    SG   I G  + +    +RK
Sbjct: 1006 LALNKLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIRK 1065

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDT 335
             +        L   ++VE  L F++ L+      S  +   R  ++ +IE+L L   R +
Sbjct: 1066 NLGMCPQHNVLFDRLTVEEHLWFYSRLK------SMAQEEIRREMDKMIEDLELSNKRHS 1119

Query: 336  NVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMS 395
             V  L+    R+L+VA   +     +ILD+PT  +D +    + + +  +   GR +++S
Sbjct: 1120 LVQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKY-KPGRTILLS 1178

Query: 396  LHPPTYEIFAMLTKVVLISAGRTMFSG 422
             H    E   +  ++ +IS G+    G
Sbjct: 1179 THHMD-EADLLGDRIAIISHGKLKCCG 1204


>AB028985-1|BAA83014.2| 1771|Homo sapiens KIAA1062 protein protein.
          Length = 1771

 Score = 55.2 bits (127), Expect = 9e-07
 Identities = 51/203 (25%), Positives = 84/203 (41%), Gaps = 11/203 (5%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTLR--K 275
            L V  L   V+ GE   +L       T    +L G      G+  +NG  V    L+  +
Sbjct: 1404 LAVDRLCLGVRPGECFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKELLQVQQ 1463

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRI-NLLIEELGLEQVRD 334
             + Y     AL   ++    L+ +  LR        +   D  R+    +E+L L +  D
Sbjct: 1464 SLGYCPQCDALFDELTAREHLQLYTRLRG-------ISWKDEARVVKWALEKLELTKYAD 1516

Query: 335  TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
               G  +    R+L+ A  L+   A + LD+PT  MD     FL   + +   TGR V++
Sbjct: 1517 KPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDLIKTGRSVVL 1576

Query: 395  SLHPPTYEIFAMLTKVVLISAGR 417
            + H    E  A+ T++ ++  GR
Sbjct: 1577 TSH-SMEECEALCTRLAIMVNGR 1598



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 47/207 (22%), Positives = 92/207 (44%), Gaps = 10/207 (4%)

Query: 218 LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST--LRK 275
           L ++ LS  +   ++++ L       T  + +L G+    SG   I G  + +    +RK
Sbjct: 341 LALNKLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIRK 400

Query: 276 VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDT 335
            +        L   ++VE  L F++ L+      S  +   R  ++ +IE+L L   R +
Sbjct: 401 NLGMCPQHNVLFDRLTVEEHLWFYSRLK------SMAQEEIRREMDKMIEDLELSNKRHS 454

Query: 336 NVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMS 395
            V  L+    R+L+VA   +     +ILD+PT  +D +    + + +  +   GR +++S
Sbjct: 455 LVQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKY-KPGRTILLS 513

Query: 396 LHPPTYEIFAMLTKVVLISAGRTMFSG 422
            H    E   +  ++ +IS G+    G
Sbjct: 514 THHMD-EADLLGDRIAIISHGKLKCCG 539


>AY028899-1|AAK30024.1| 1624|Homo sapiens ATP-binding cassette A9
            protein.
          Length = 1624

 Score = 53.2 bits (122), Expect = 4e-06
 Identities = 45/206 (21%), Positives = 94/206 (45%), Gaps = 10/206 (4%)

Query: 213  ENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST 272
            + K T+    +SF VK GE++ +L       +  + ++ G  K  +G +++ G       
Sbjct: 1302 KRKKTIATRNVSFCVKKGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVILKGS--GGGE 1359

Query: 273  LRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQV 332
                + Y   + AL P ++V   L  +AA++  R   + +       I  L++ L L+  
Sbjct: 1360 PLGFLGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAMI------AITRLVDALKLQDQ 1413

Query: 333  RDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLR-NWASTGRV 391
                V  L+    R+L     +L + ++++LD+P+  MD      + + +R  + +T R 
Sbjct: 1414 LKAPVKTLSEGIKRKLRFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQVIRATFRNTERG 1473

Query: 392  VIMSLHPPTYEIFAMLTKVVLISAGR 417
             +++ H    E  A+  +V ++ +GR
Sbjct: 1474 ALLTTHYMA-EAEAVCDRVAIMVSGR 1498



 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 45/204 (22%), Positives = 89/204 (43%), Gaps = 6/204 (2%)

Query: 220 VSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTLRKVVAY 279
           + G+ F++  G+I A+L  +    T LL++L+G+    SG + +    ++       +  
Sbjct: 500 LKGVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTSGSVTVYNHTLSRMA---DIEN 556

Query: 280 VRNDTALCPTMSVEHT-LRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVG 338
           +   T  CP  +V+   L     LR        +       +  +++EL +E ++D    
Sbjct: 557 ISKFTGFCPQSNVQFGFLTVKENLRLFAKIKGILPHEVEKEVQRVVQELEMENIQDILAQ 616

Query: 339 RLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHP 398
            L+  + R+L     +L D  +L+LD+PT  +D      +   L+    + RV++ S   
Sbjct: 617 NLSGGQNRKLTFGIAILGDPQVLLLDEPTAGLDPLSRHRIWNLLKE-GKSDRVILFSTQ- 674

Query: 399 PTYEIFAMLTKVVLISAGRTMFSG 422
              E   +  + V IS G+   +G
Sbjct: 675 FIDEADILADRKVFISNGKLKCAG 698


>BC130280-1|AAI30281.1| 1621|Homo sapiens ABCA8 protein protein.
          Length = 1621

 Score = 52.8 bits (121), Expect = 5e-06
 Identities = 46/206 (22%), Positives = 96/206 (46%), Gaps = 10/206 (4%)

Query: 213  ENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST 272
            + K+ +    +SF V+ GE+L +L       +  + V+ G  K  +G +++ G       
Sbjct: 1299 KRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGS--GGGD 1356

Query: 273  LRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQV 332
              + + Y   + AL P ++V   L  +AA++  R   + V       I  L++ L L+  
Sbjct: 1357 ALEFLGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAEV------AITRLVDALKLQDQ 1410

Query: 333  RDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLR-NWASTGRV 391
              + V  L+    R+L     +L + ++++LD+P+  MD      + + +R  + +T R 
Sbjct: 1411 LKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERG 1470

Query: 392  VIMSLHPPTYEIFAMLTKVVLISAGR 417
             +++ H    E  A+  +V ++ +GR
Sbjct: 1471 ALLTTHYMA-EAEAVCDRVAIMVSGR 1495



 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 45/201 (22%), Positives = 88/201 (43%), Gaps = 6/201 (2%)

Query: 223 LSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTLRKVVAYVRN 282
           L F++  G+I A+L  +    + LL++L+G+     G + I    ++     + ++ +  
Sbjct: 502 LVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLENLSKL-- 559

Query: 283 DTALCPTMSVEHT-LRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGRLT 341
            T +CP  +V+   L     LR        +       I  ++ EL ++ ++D     L+
Sbjct: 560 -TGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEVDKEIQRVLLELEMKNIQDVLAQNLS 618

Query: 342 RSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTY 401
             + R+L     +L D  I +LD+PT  +D F    +   L+    T RV++ S      
Sbjct: 619 GGQKRKLTFGIAILGDPQIFLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMD- 676

Query: 402 EIFAMLTKVVLISAGRTMFSG 422
           E   +  + V +S G+   +G
Sbjct: 677 EADILADRKVFLSQGKLKCAG 697


>AB020629-1|BAA74845.2| 1591|Homo sapiens KIAA0822 protein protein.
          Length = 1591

 Score = 52.8 bits (121), Expect = 5e-06
 Identities = 46/206 (22%), Positives = 96/206 (46%), Gaps = 10/206 (4%)

Query: 213  ENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST 272
            + K+ +    +SF V+ GE+L +L       +  + V+ G  K  +G +++ G       
Sbjct: 1269 KRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGS--GGGD 1326

Query: 273  LRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQV 332
              + + Y   + AL P ++V   L  +AA++  R   + V       I  L++ L L+  
Sbjct: 1327 ALEFLGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAEV------AITRLVDALKLQDQ 1380

Query: 333  RDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLR-NWASTGRV 391
              + V  L+    R+L     +L + ++++LD+P+  MD      + + +R  + +T R 
Sbjct: 1381 LKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERG 1440

Query: 392  VIMSLHPPTYEIFAMLTKVVLISAGR 417
             +++ H    E  A+  +V ++ +GR
Sbjct: 1441 ALLTTHYMA-EAEAVCDRVAIMVSGR 1465


>AK074491-1|BAC11021.1|  483|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90010 fis, clone HEMBA1000349, weakly similar to
           ATP-BINDING CASSETTE TRANSPORTER 1. ).
          Length = 483

 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 45/204 (22%), Positives = 89/204 (43%), Gaps = 6/204 (2%)

Query: 220 VSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTLRKVVAY 279
           + G+ F++  G+I A+L  +    T LL++L+G+    SG + +    ++       +  
Sbjct: 127 LKGVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTSGSVTVYNHTLSRMA---DIEN 183

Query: 280 VRNDTALCPTMSVEHT-LRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVG 338
           +   T  CP  +V+   L     LR        +       +  +++EL +E ++D    
Sbjct: 184 ISKFTGFCPQSNVQFGFLTVKENLRLFAKIKGILPHEVEKEVQRVVQELEMENIQDILAQ 243

Query: 339 RLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHP 398
            L+  + R+L     +L D  +L+LD+PT  +D      +   L+    + RV++ S   
Sbjct: 244 NLSGGQNRKLTFGIAILGDPQVLLLDEPTAGLDPLSRHRIWNLLKE-GKSDRVILFSTQ- 301

Query: 399 PTYEIFAMLTKVVLISAGRTMFSG 422
              E   +  + V IS G+   +G
Sbjct: 302 FIDEADILADRKVFISNGKLKCAG 325


>AK057068-1|BAB71359.1|  856|Homo sapiens protein ( Homo sapiens
           cDNA FLJ32506 fis, clone SMINT1000042, weakly similar to
           ATP-BINDING CASSETTE, SUB-FAMILY A, MEMBER 3. ).
          Length = 856

 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 45/204 (22%), Positives = 89/204 (43%), Gaps = 6/204 (2%)

Query: 220 VSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTLRKVVAY 279
           + G+ F++  G+I A+L  +    T LL++L+G+    SG + +    ++       +  
Sbjct: 500 LKGVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTSGSVTVYNHTLSRMA---DIEN 556

Query: 280 VRNDTALCPTMSVEHT-LRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVG 338
           +   T  CP  +V+   L     LR        +       +  +++EL +E ++D    
Sbjct: 557 ISKFTGFCPQSNVQFGFLTVKENLRLFAKIKGILPHEVEKEVQRVVQELEMENIQDILAQ 616

Query: 339 RLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHP 398
            L+  + R+L     +L D  +L+LD+PT  +D      +   L+    + RV++ S   
Sbjct: 617 NLSGGQNRKLTFGIAILGDPQVLLLDEPTAGLDPLSRHRIWNLLKE-GKSDRVILFSTQ- 674

Query: 399 PTYEIFAMLTKVVLISAGRTMFSG 422
              E   +  + V IS G+   +G
Sbjct: 675 FIDEADILADRKVFISNGKLKCAG 698


>AF423346-1|AAN32752.1| 1624|Homo sapiens ATP-binding cassette
           sub-family A member 9 protein.
          Length = 1624

 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 45/204 (22%), Positives = 89/204 (43%), Gaps = 6/204 (2%)

Query: 220 VSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTLRKVVAY 279
           + G+ F++  G+I A+L  +    T LL++L+G+    SG + +    ++       +  
Sbjct: 500 LKGVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTSGSVTVYNHTLSRMA---DIEN 556

Query: 280 VRNDTALCPTMSVEHT-LRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVG 338
           +   T  CP  +V+   L     LR        +       +  +++EL +E ++D    
Sbjct: 557 ISKFTGFCPQSNVQFGFLTVKENLRLFAKIKGILPHEVEKEVQRVVQELEMENIQDILAQ 616

Query: 339 RLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHP 398
            L+  + R+L     +L D  +L+LD+PT  +D      +   L+    + RV++ S   
Sbjct: 617 NLSGGQNRKLTFGIAILGDPQVLLLDEPTAGLDPLSRHRIWNLLKE-GKSDRVILFSTQ- 674

Query: 399 PTYEIFAMLTKVVLISAGRTMFSG 422
              E   +  + V IS G+   +G
Sbjct: 675 FIDEADILADRKVFISNGKLKCAG 698



 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 44/206 (21%), Positives = 93/206 (45%), Gaps = 10/206 (4%)

Query: 213  ENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST 272
            + K  +    +SF VK GE++ +L       +  + ++ G  K  +G +++ G       
Sbjct: 1302 KRKKKIATRNVSFCVKKGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVILKGS--GGGE 1359

Query: 273  LRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQV 332
                + Y   + AL P ++V   L  +AA++  R   + +       I  L++ L L+  
Sbjct: 1360 PLGFLGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAMI------AITRLVDALKLQDQ 1413

Query: 333  RDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLR-NWASTGRV 391
                V  L+    R+L     +L + ++++LD+P+  MD      + + +R  + +T R 
Sbjct: 1414 LKAPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQVIRATFRNTERG 1473

Query: 392  VIMSLHPPTYEIFAMLTKVVLISAGR 417
             +++ H    E  A+  +V ++ +GR
Sbjct: 1474 ALLTTHYMA-EAEAVCDRVAIMVSGR 1498


>AF423307-1|AAN32751.1| 1624|Homo sapiens ATP-binding cassette
           sub-family A member 9 protein.
          Length = 1624

 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 45/204 (22%), Positives = 89/204 (43%), Gaps = 6/204 (2%)

Query: 220 VSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTLRKVVAY 279
           + G+ F++  G+I A+L  +    T LL++L+G+    SG + +    ++       +  
Sbjct: 500 LKGVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTSGSVTVYNHTLSRMA---DIEN 556

Query: 280 VRNDTALCPTMSVEHT-LRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVG 338
           +   T  CP  +V+   L     LR        +       +  +++EL +E ++D    
Sbjct: 557 ISKFTGFCPQSNVQFGFLTVKENLRLFAKIKGILPHEVEKEVQRVVQELEMENIQDILAQ 616

Query: 339 RLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHP 398
            L+  + R+L     +L D  +L+LD+PT  +D      +   L+    + RV++ S   
Sbjct: 617 NLSGGQNRKLTFGIAILGDPQVLLLDEPTAGLDPLSRHRIWNLLKE-GKSDRVILFSTQ- 674

Query: 399 PTYEIFAMLTKVVLISAGRTMFSG 422
              E   +  + V IS G+   +G
Sbjct: 675 FIDEADILADRKVFISNGKLKCAG 698



 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 44/206 (21%), Positives = 93/206 (45%), Gaps = 10/206 (4%)

Query: 213  ENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST 272
            + K  +    +SF VK GE++ +L       +  + ++ G  K  +G +++ G       
Sbjct: 1302 KRKKKIATRNVSFCVKKGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVILKGS--GGGE 1359

Query: 273  LRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQV 332
                + Y   + AL P ++V   L  +AA++  R   + +       I  L++ L L+  
Sbjct: 1360 PLGFLGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAMI------AITRLVDALKLQDQ 1413

Query: 333  RDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLR-NWASTGRV 391
                V  L+    R+L     +L + ++++LD+P+  MD      + + +R  + +T R 
Sbjct: 1414 LKAPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQVIRATFRNTERG 1473

Query: 392  VIMSLHPPTYEIFAMLTKVVLISAGR 417
             +++ H    E  A+  +V ++ +GR
Sbjct: 1474 ALLTTHYMA-EAEAVCDRVAIMVSGR 1498


>AL359846-6|CAH73579.1| 2261|Homo sapiens ATP-binding cassette,
            sub-family A (ABC1), memberisiae) protein.
          Length = 2261

 Score = 52.0 bits (119), Expect = 8e-06
 Identities = 51/203 (25%), Positives = 96/203 (47%), Gaps = 11/203 (5%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS--STLRK 275
            + V GL+     G+I + L       T  + +L G+    SG   I G+ + S  ST+R+
Sbjct: 914  VAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQ 973

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVR-D 334
             +        L   ++VE  + F+A L+    +  HVK  + +++ L   ++GL   +  
Sbjct: 974  NLGVCPQHNVLFDMLTVEEHIWFYARLKGL--SEKHVK-AEMEQMAL---DVGLPSSKLK 1027

Query: 335  TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
            +   +L+    R+L+VA   +    ++ILD+PT  +D +    + E L  +   GR +I+
Sbjct: 1028 SKTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQ-GRTIIL 1086

Query: 395  SLHPPTYEIFAMLTKVVLISAGR 417
            S H    E   +  ++ +IS G+
Sbjct: 1087 STHHMD-EADVLGDRIAIISHGK 1108



 Score = 39.5 bits (88), Expect = 0.047
 Identities = 43/190 (22%), Positives = 77/190 (40%), Gaps = 9/190 (4%)

Query: 230  GEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST--LRKVVAYVRNDTALC 287
            GE   +L       +    +L G      GD  +N   + S+   + + + Y     A+ 
Sbjct: 1939 GECFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKNSILSNIHEVHQNMGYCPQFDAIT 1998

Query: 288  PTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGRLTRSEIRR 347
              ++    + F A LR         K+G+       I +LGL +  +   G  +    R+
Sbjct: 1999 ELLTGREHVEFFALLRGVPEKEVG-KVGE-----WAIRKLGLVKYGEKYAGNYSGGNKRK 2052

Query: 348  LNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAML 407
            L+ A  L+    ++ LD+PT  MD     FL     +    GR V+++ H    E  A+ 
Sbjct: 2053 LSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSVVKEGRSVVLTSH-SMEECEALC 2111

Query: 408  TKVVLISAGR 417
            T++ ++  GR
Sbjct: 2112 TRMAIMVNGR 2121


>AL353685-3|CAH72444.1| 2261|Homo sapiens ATP-binding cassette,
            sub-family A (ABC1), memberog, Drosophila) protein.
          Length = 2261

 Score = 52.0 bits (119), Expect = 8e-06
 Identities = 51/203 (25%), Positives = 96/203 (47%), Gaps = 11/203 (5%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS--STLRK 275
            + V GL+     G+I + L       T  + +L G+    SG   I G+ + S  ST+R+
Sbjct: 914  VAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQ 973

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVR-D 334
             +        L   ++VE  + F+A L+    +  HVK  + +++ L   ++GL   +  
Sbjct: 974  NLGVCPQHNVLFDMLTVEEHIWFYARLKGL--SEKHVK-AEMEQMAL---DVGLPSSKLK 1027

Query: 335  TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
            +   +L+    R+L+VA   +    ++ILD+PT  +D +    + E L  +   GR +I+
Sbjct: 1028 SKTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQ-GRTIIL 1086

Query: 395  SLHPPTYEIFAMLTKVVLISAGR 417
            S H    E   +  ++ +IS G+
Sbjct: 1087 STHHMD-EADVLGDRIAIISHGK 1108



 Score = 39.5 bits (88), Expect = 0.047
 Identities = 43/190 (22%), Positives = 77/190 (40%), Gaps = 9/190 (4%)

Query: 230  GEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST--LRKVVAYVRNDTALC 287
            GE   +L       +    +L G      GD  +N   + S+   + + + Y     A+ 
Sbjct: 1939 GECFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKNSILSNIHEVHQNMGYCPQFDAIT 1998

Query: 288  PTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGRLTRSEIRR 347
              ++    + F A LR         K+G+       I +LGL +  +   G  +    R+
Sbjct: 1999 ELLTGREHVEFFALLRGVPEKEVG-KVGE-----WAIRKLGLVKYGEKYAGNYSGGNKRK 2052

Query: 348  LNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAML 407
            L+ A  L+    ++ LD+PT  MD     FL     +    GR V+++ H    E  A+ 
Sbjct: 2053 LSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSVVKEGRSVVLTSH-SMEECEALC 2111

Query: 408  TKVVLISAGR 417
            T++ ++  GR
Sbjct: 2112 TRMAIMVNGR 2121


>AK130814-1|BAC85435.1|  546|Homo sapiens protein ( Homo sapiens
           cDNA FLJ27304 fis, clone TMS05176, highly similar to
           ATP-binding cassette, sub-family A, member 1. ).
          Length = 546

 Score = 52.0 bits (119), Expect = 8e-06
 Identities = 51/203 (25%), Positives = 96/203 (47%), Gaps = 11/203 (5%)

Query: 218 LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS--STLRK 275
           + V GL+     G+I + L       T  + +L G+    SG   I G+ + S  ST+R+
Sbjct: 88  VAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQ 147

Query: 276 VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVR-D 334
            +        L   ++VE  + F+A L+    +  HVK  + +++ L   ++GL   +  
Sbjct: 148 NLGVCPQHNVLFDMLTVEEHIWFYARLKGL--SEKHVK-AEMEQMAL---DVGLPSSKLK 201

Query: 335 TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
           +   +L+    R+L+VA   +    ++ILD+PT  +D +    + E L  +   GR +I+
Sbjct: 202 SKTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQ-GRTIIL 260

Query: 395 SLHPPTYEIFAMLTKVVLISAGR 417
           S H    E   +  ++ +IS G+
Sbjct: 261 STHHMD-EADVLGDRIAIISHGK 282


>AJ012376-1|CAA10005.1| 2201|Homo sapiens ATP-binding cassette
            transporter-1 (ABC-1) protein.
          Length = 2201

 Score = 52.0 bits (119), Expect = 8e-06
 Identities = 51/203 (25%), Positives = 96/203 (47%), Gaps = 11/203 (5%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS--STLRK 275
            + V GL+     G+I + L       T  + +L G+    SG   I G+ + S  ST+R+
Sbjct: 854  VAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQ 913

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVR-D 334
             +        L   ++VE  + F+A L+    +  HVK  + +++ L   ++GL   +  
Sbjct: 914  NLGVCPQHNVLFDMLTVEEHIWFYARLKGL--SEKHVK-AEMEQMAL---DVGLPSSKLK 967

Query: 335  TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
            +   +L+    R+L+VA   +    ++ILD+PT  +D +    + E L  +   GR +I+
Sbjct: 968  SKTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQ-GRTIIL 1026

Query: 395  SLHPPTYEIFAMLTKVVLISAGR 417
            S H    E   +  ++ +IS G+
Sbjct: 1027 STHHMD-EADVLGDRIAIISHGK 1048



 Score = 39.5 bits (88), Expect = 0.047
 Identities = 43/190 (22%), Positives = 77/190 (40%), Gaps = 9/190 (4%)

Query: 230  GEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST--LRKVVAYVRNDTALC 287
            GE   +L       +    +L G      GD  +N   + S+   + + + Y     A+ 
Sbjct: 1879 GECFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNRNSILSNIHEVHQNMGYCPQFDAIT 1938

Query: 288  PTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGRLTRSEIRR 347
              ++    + F A LR         K+G+       I +LGL +  +   G  +    R+
Sbjct: 1939 ELLTGREHVEFFALLRGVPEKEVG-KVGE-----WAIRKLGLVKYGEKYAGNYSGGNKRK 1992

Query: 348  LNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAML 407
            L+ A  L+    ++ LD+PT  MD     FL     +    GR V+++ H    E  A+ 
Sbjct: 1993 LSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSVVKEGRSVVLTSH-SMEECEALC 2051

Query: 408  TKVVLISAGR 417
            T++ ++  GR
Sbjct: 2052 TRMAIMVNGR 2061


>AF285167-1|AAF98175.1| 2261|Homo sapiens ATP-binding cassette
            transporter 1 protein.
          Length = 2261

 Score = 52.0 bits (119), Expect = 8e-06
 Identities = 51/203 (25%), Positives = 96/203 (47%), Gaps = 11/203 (5%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS--STLRK 275
            + V GL+     G+I + L       T  + +L G+    SG   I G+ + S  ST+R+
Sbjct: 914  VAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQ 973

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVR-D 334
             +        L   ++VE  + F+A L+    +  HVK  + +++ L   ++GL   +  
Sbjct: 974  NLGVCPQHNVLFDMLTVEEHIWFYARLKGL--SEKHVK-AEMEQMAL---DVGLPSSKLK 1027

Query: 335  TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
            +   +L+    R+L+VA   +    ++ILD+PT  +D +    + E L  +   GR +I+
Sbjct: 1028 SKTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQ-GRTIIL 1086

Query: 395  SLHPPTYEIFAMLTKVVLISAGR 417
            S H    E   +  ++ +IS G+
Sbjct: 1087 STHHMD-EADVLGDRIAIISHGK 1108



 Score = 39.5 bits (88), Expect = 0.047
 Identities = 43/190 (22%), Positives = 77/190 (40%), Gaps = 9/190 (4%)

Query: 230  GEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST--LRKVVAYVRNDTALC 287
            GE   +L       +    +L G      GD  +N   + S+   + + + Y     A+ 
Sbjct: 1939 GECFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKNSILSNIHEVHQNMGYCPQFDAIT 1998

Query: 288  PTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGRLTRSEIRR 347
              ++    + F A LR         K+G+       I +LGL +  +   G  +    R+
Sbjct: 1999 ELLTGREHVEFFALLRGVPEKEVG-KVGE-----WAIRKLGLVKYGEKYAGNYSGGNKRK 2052

Query: 348  LNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAML 407
            L+ A  L+    ++ LD+PT  MD     FL     +    GR V+++ H    E  A+ 
Sbjct: 2053 LSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSVVKEGRSVVLTSH-SMEECEALC 2111

Query: 408  TKVVLISAGR 417
            T++ ++  GR
Sbjct: 2112 TRMAIMVNGR 2121


>AF275948-1|AAF86276.1| 2261|Homo sapiens ABCA1 protein.
          Length = 2261

 Score = 52.0 bits (119), Expect = 8e-06
 Identities = 51/203 (25%), Positives = 96/203 (47%), Gaps = 11/203 (5%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS--STLRK 275
            + V GL+     G+I + L       T  + +L G+    SG   I G+ + S  ST+R+
Sbjct: 914  VAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQ 973

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVR-D 334
             +        L   ++VE  + F+A L+    +  HVK  + +++ L   ++GL   +  
Sbjct: 974  NLGVCPQHNVLFDMLTVEEHIWFYARLKGL--SEKHVK-AEMEQMAL---DVGLPSSKLK 1027

Query: 335  TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
            +   +L+    R+L+VA   +    ++ILD+PT  +D +    + E L  +   GR +I+
Sbjct: 1028 SKTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQ-GRTIIL 1086

Query: 395  SLHPPTYEIFAMLTKVVLISAGR 417
            S H    E   +  ++ +IS G+
Sbjct: 1087 STHHMD-EADVLGDRIAIISHGK 1108



 Score = 39.9 bits (89), Expect = 0.036
 Identities = 43/190 (22%), Positives = 77/190 (40%), Gaps = 9/190 (4%)

Query: 230  GEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST--LRKVVAYVRNDTALC 287
            GE   +L       +    +L G      GD  +N   + S+   + + + Y     A+ 
Sbjct: 1939 GECFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNXNSILSNIHEVHQNMGYCPQFDAIT 1998

Query: 288  PTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGRLTRSEIRR 347
              ++    + F A LR         K+G+       I +LGL +  +   G  +    R+
Sbjct: 1999 ELLTGREHVEFFALLRGVPEKEVG-KVGE-----WAIRKLGLVKYGEKYAGNYSGGNKRK 2052

Query: 348  LNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAML 407
            L+ A  L+    ++ LD+PT  MD     FL     +    GR V+++ H    E  A+ 
Sbjct: 2053 LSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSVVKEGRSVVLTSH-SMEECEALC 2111

Query: 408  TKVVLISAGR 417
            T++ ++  GR
Sbjct: 2112 TRMAIMVNGR 2121


>AF165281-1|AAD49849.1| 2201|Homo sapiens ATP cassette binding
            transporter 1 protein.
          Length = 2201

 Score = 52.0 bits (119), Expect = 8e-06
 Identities = 51/203 (25%), Positives = 96/203 (47%), Gaps = 11/203 (5%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS--STLRK 275
            + V GL+     G+I + L       T  + +L G+    SG   I G+ + S  ST+R+
Sbjct: 854  VAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQ 913

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVR-D 334
             +        L   ++VE  + F+A L+    +  HVK  + +++ L   ++GL   +  
Sbjct: 914  NLGVCPQHNVLFDMLTVEEHIWFYARLKGL--SEKHVK-AEMEQMAL---DVGLPSSKLK 967

Query: 335  TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
            +   +L+    R+L+VA   +    ++ILD+PT  +D +    + E L  +   GR +I+
Sbjct: 968  SKTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQ-GRTIIL 1026

Query: 395  SLHPPTYEIFAMLTKVVLISAGR 417
            S H    E   +  ++ +IS G+
Sbjct: 1027 STHHMD-EADVLGDRIAIISHGK 1048



 Score = 39.5 bits (88), Expect = 0.047
 Identities = 43/190 (22%), Positives = 77/190 (40%), Gaps = 9/190 (4%)

Query: 230  GEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST--LRKVVAYVRNDTALC 287
            GE   +L       +    +L G      GD  +N   + S+   + + + Y     A+ 
Sbjct: 1879 GECFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNRNSILSNIHEVHQNMGYCPQFDAIT 1938

Query: 288  PTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGRLTRSEIRR 347
              ++    + F A LR         K+G+       I +LGL +  +   G  +    R+
Sbjct: 1939 ELLTGREHVEFFALLRGVPEKEVG-KVGE-----WAIRKLGLVKYGEKYAGNYSGGNKRK 1992

Query: 348  LNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAML 407
            L+ A  L+    ++ LD+PT  MD     FL     +    GR V+++ H    E  A+ 
Sbjct: 1993 LSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSVVKEGRSVVLTSH-SMEECEALC 2051

Query: 408  TKVVLISAGR 417
            T++ ++  GR
Sbjct: 2052 TRMAIMVNGR 2061


>AB055982-1|BAB63210.1| 2261|Homo sapiens ABCA1 protein.
          Length = 2261

 Score = 52.0 bits (119), Expect = 8e-06
 Identities = 51/203 (25%), Positives = 96/203 (47%), Gaps = 11/203 (5%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS--STLRK 275
            + V GL+     G+I + L       T  + +L G+    SG   I G+ + S  ST+R+
Sbjct: 914  VAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQ 973

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVR-D 334
             +        L   ++VE  + F+A L+    +  HVK  + +++ L   ++GL   +  
Sbjct: 974  NLGVCPQHNVLFDMLTVEEHIWFYARLKGL--SEKHVK-AEMEQMAL---DVGLPSSKLK 1027

Query: 335  TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
            +   +L+    R+L+VA   +    ++ILD+PT  +D +    + E L  +   GR +I+
Sbjct: 1028 SKTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQ-GRTIIL 1086

Query: 395  SLHPPTYEIFAMLTKVVLISAGR 417
            S H    E   +  ++ +IS G+
Sbjct: 1087 STHHMD-EADVLGDRIAIISHGK 1108



 Score = 39.5 bits (88), Expect = 0.047
 Identities = 43/190 (22%), Positives = 77/190 (40%), Gaps = 9/190 (4%)

Query: 230  GEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST--LRKVVAYVRNDTALC 287
            GE   +L       +    +L G      GD  +N   + S+   + + + Y     A+ 
Sbjct: 1939 GECFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKNSILSNIHEVHQNMGYCPQFDAIT 1998

Query: 288  PTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGRLTRSEIRR 347
              ++    + F A LR         K+G+       I +LGL +  +   G  +    R+
Sbjct: 1999 ELLTGREHVEFFALLRGVPEKEVG-KVGE-----WAIRKLGLVKYGEKYAGNYSGGNKRK 2052

Query: 348  LNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAML 407
            L+ A  L+    ++ LD+PT  MD     FL     +    GR V+++ H    E  A+ 
Sbjct: 2053 LSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSVVKEGRSVVLTSH-SMEECEALC 2111

Query: 408  TKVVLISAGR 417
            T++ ++  GR
Sbjct: 2112 TRMAIMVNGR 2121


>AK097296-1|BAC04994.1|  815|Homo sapiens protein ( Homo sapiens
           cDNA FLJ39977 fis, clone SPLEN2029295, moderately
           similar to ATP-binding cassette, sub-family A member 8.
           ).
          Length = 815

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 49/206 (23%), Positives = 97/206 (47%), Gaps = 12/206 (5%)

Query: 213 ENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST 272
           + K  +    +SF V+ GEIL +L  +    +  + +++G+ K  +G++ + G    SS 
Sbjct: 494 KRKKKIAARNISFCVQEGEILGLLGPSGAGKSSSIRMISGITKPTAGEVELKG---CSSV 550

Query: 273 LRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQV 332
           L   + Y   +  L P +++   L  +AA++  R      K   R  I  L+    L + 
Sbjct: 551 LGH-LGYCPQENVLWPMLTLREHLEVYAAVKGLR------KADARLAIARLVSAFKLHEQ 603

Query: 333 RDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWA-STGRV 391
            +  V +LT    R+L     LL +  +L+LD+P+  +D      + + ++    +T R 
Sbjct: 604 LNVPVQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERG 663

Query: 392 VIMSLHPPTYEIFAMLTKVVLISAGR 417
           V+++ H    E  A+  +V ++ +GR
Sbjct: 664 VLLTTH-NLAEAEALCDRVAIMVSGR 688


>AF287262-1|AAK43526.1| 2261|Homo sapiens ATP-binding cassette 1
            sub-family A member 1 protein.
          Length = 2261

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 50/203 (24%), Positives = 94/203 (46%), Gaps = 11/203 (5%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS--STLRK 275
            + V GL+     G+I + L       T  + +L G+    SG   I G+ + S  ST+R+
Sbjct: 914  VAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQ 973

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVR-D 334
             +        L   ++VE  + F+A L+     H   +M   +++ L   ++GL   +  
Sbjct: 974  NLGVCPQHNVLFDMLTVEEHIWFYARLKGLSKKHVKAEM---EQMAL---DVGLPSSKLK 1027

Query: 335  TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
            +   +L+    R+L+VA   +    ++ILD+PT  +D +    + E L  +   GR +I+
Sbjct: 1028 SKTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQ-GRTIIL 1086

Query: 395  SLHPPTYEIFAMLTKVVLISAGR 417
            S H    E   +  ++ +IS G+
Sbjct: 1087 STHHMD-EADVLGDRIAIISHGK 1108



 Score = 39.5 bits (88), Expect = 0.047
 Identities = 43/190 (22%), Positives = 77/190 (40%), Gaps = 9/190 (4%)

Query: 230  GEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST--LRKVVAYVRNDTALC 287
            GE   +L       +    +L G      GD  +N   + S+   + + + Y     A+ 
Sbjct: 1939 GECFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKNSILSNIHEVHQNMGYCPQFDAIT 1998

Query: 288  PTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGRLTRSEIRR 347
              ++    + F A LR         K+G+       I +LGL +  +   G  +    R+
Sbjct: 1999 ELLTGREHVEFFALLRGVPEKEVG-KVGE-----WAIRKLGLVKYGEKYAGNYSGGNKRK 2052

Query: 348  LNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAML 407
            L+ A  L+    ++ LD+PT  MD     FL     +    GR V+++ H    E  A+ 
Sbjct: 2053 LSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSVVKEGRSVVLTSH-SMEECEALC 2111

Query: 408  TKVVLISAGR 417
            T++ ++  GR
Sbjct: 2112 TRMAIMVNGR 2121


>X97187-1|CAA65825.1| 1704|Homo sapiens ABC-C transporter protein.
          Length = 1704

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 53/218 (24%), Positives = 92/218 (42%), Gaps = 9/218 (4%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST--LRK 275
            L V  LS  V+ GE   +L       T    +L G     SGD  + G  ++S    +R+
Sbjct: 1397 LAVDRLSLAVQKGECFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVGGHRISSDVGKVRQ 1456

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDT 335
             + Y     AL   M+    L  +A LR     H    + +  R  LL+E    + VR  
Sbjct: 1457 RIGYCPQFDALLDHMTGREMLVMYARLRGIPERHIGACVENTLR-GLLLEPHANKLVRTY 1515

Query: 336  NVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMS 395
            + G       R+L+    L+ + A++ LD+P+  MD      L + +     +G+ +I++
Sbjct: 1516 SGGNK-----RKLSTGIALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKAIIIT 1570

Query: 396  LHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSS 433
             H    E  A+ T++ ++  G+    G  + +   F S
Sbjct: 1571 SH-SMEECEALCTRLAIMVQGQFKCLGSPQHLKSKFGS 1607



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 44/186 (23%), Positives = 80/186 (43%), Gaps = 9/186 (4%)

Query: 214 NKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST- 272
           NK    V  L+  +  G+I  +L       T  L +L G+    SG   I+G  ++    
Sbjct: 543 NKDRAAVRDLNLNLYEGQITVLLGHNGAGKTTTLSMLTGLFPPTSGRAYISGYEISQDMV 602

Query: 273 -LRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQ 331
            +RK +        L   ++V   L F+A L+      S  K  +   +  ++  +GLE 
Sbjct: 603 QIRKSLGLCPQHDILFDNLTVAEHLYFYAQLKGL----SRQKCPEE--VKQMLHIIGLED 656

Query: 332 VRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRV 391
             ++    L+    R+L++   L+    +LILD+PT  MD      + + L+   S  R 
Sbjct: 657 KWNSRSRFLSGGMRRKLSIGIALIAGSKVLILDEPTSGMDAISRRAIWDLLQRQKS-DRT 715

Query: 392 VIMSLH 397
           ++++ H
Sbjct: 716 IVLTTH 721


>U78735-1|AAC50967.1| 1704|Homo sapiens ABC3 protein.
          Length = 1704

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 53/218 (24%), Positives = 92/218 (42%), Gaps = 9/218 (4%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST--LRK 275
            L V  LS  V+ GE   +L       T    +L G     SGD  + G  ++S    +R+
Sbjct: 1397 LAVDRLSLAVQKGECFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVGGHRISSDVGKVRQ 1456

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDT 335
             + Y     AL   M+    L  +A LR     H    + +  R  LL+E    + VR  
Sbjct: 1457 RIGYCPQFDALLDHMTGREMLVMYARLRGIPERHIGACVENTLR-GLLLEPHANKLVRTY 1515

Query: 336  NVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMS 395
            + G       R+L+    L+ + A++ LD+P+  MD      L + +     +G+ +I++
Sbjct: 1516 SGGNK-----RKLSTGIALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKAIIIT 1570

Query: 396  LHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSS 433
             H    E  A+ T++ ++  G+    G  + +   F S
Sbjct: 1571 SH-SMEECEALCTRLAIMVQGQFKCLGSPQHLKSKFGS 1607



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 44/186 (23%), Positives = 80/186 (43%), Gaps = 9/186 (4%)

Query: 214 NKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST- 272
           NK    V  L+  +  G+I  +L       T  L +L G+    SG   I+G  ++    
Sbjct: 543 NKDRAAVRDLNLNLYEGQITVLLGHNGAGKTTTLSMLTGLFPPTSGRAYISGYEISQDMV 602

Query: 273 -LRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQ 331
            +RK +        L   ++V   L F+A L+      S  K  +   +  ++  +GLE 
Sbjct: 603 QIRKSLGLCPQHDILFDNLTVAEHLYFYAQLKGL----SRQKCPEE--VKQMLHIIGLED 656

Query: 332 VRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRV 391
             ++    L+    R+L++   L+    +LILD+PT  MD      + + L+   S  R 
Sbjct: 657 KWNSRSRFLSGGMRRKLSIGIALIAGSKVLILDEPTSGMDAISRRAIWDLLQRQKS-DRT 715

Query: 392 VIMSLH 397
           ++++ H
Sbjct: 716 IVLTTH 721


>DQ073080-1|AAY57325.1| 1704|Homo sapiens ATP-binding cassette,
            sub-family A (ABC1), member 3 protein.
          Length = 1704

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 53/218 (24%), Positives = 92/218 (42%), Gaps = 9/218 (4%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST--LRK 275
            L V  LS  V+ GE   +L       T    +L G     SGD  + G  ++S    +R+
Sbjct: 1397 LAVDRLSLAVQKGECFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVGGHRISSDVGKVRQ 1456

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDT 335
             + Y     AL   M+    L  +A LR     H    + +  R  LL+E    + VR  
Sbjct: 1457 RIGYCPQFDALLDHMTGREMLVMYARLRGIPERHIGACVENTLR-GLLLEPHANKLVRTY 1515

Query: 336  NVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMS 395
            + G       R+L+    L+ + A++ LD+P+  MD      L + +     +G+ +I++
Sbjct: 1516 SGGNK-----RKLSTGIALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKAIIIT 1570

Query: 396  LHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSS 433
             H    E  A+ T++ ++  G+    G  + +   F S
Sbjct: 1571 SH-SMEECEALCTRLAIMVQGQFKCLGSPQHLKSKFGS 1607



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 44/186 (23%), Positives = 80/186 (43%), Gaps = 9/186 (4%)

Query: 214 NKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST- 272
           NK    V  L+  +  G+I  +L       T  L +L G+    SG   I+G  ++    
Sbjct: 543 NKDRAAVRDLNLNLYEGQITVLLGHNGAGKTTTLSMLTGLFPPTSGRAYISGYEISQDMV 602

Query: 273 -LRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQ 331
            +RK +        L   ++V   L F+A L+      S  K  +   +  ++  +GLE 
Sbjct: 603 QIRKSLGLCPQHDILFDNLTVAEHLYFYAQLKGL----SRQKCPEE--VKQMLHIIGLED 656

Query: 332 VRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRV 391
             ++    L+    R+L++   L+    +LILD+PT  MD      + + L+   S  R 
Sbjct: 657 KWNSRSRFLSGGMRRKLSIGIALIAGSKVLILDEPTSGMDAISRRAIWDLLQRQKS-DRT 715

Query: 392 VIMSLH 397
           ++++ H
Sbjct: 716 IVLTTH 721


>AY247105-1|AAO72160.1| 1543|Homo sapiens ATP-binding cassette
           sub-family A member 10 protein.
          Length = 1543

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 38/160 (23%), Positives = 75/160 (46%), Gaps = 14/160 (8%)

Query: 220 VSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST----LRK 275
           + G+ F++  G+I A+L       + LL++L+G+     G   I    ++  T    +RK
Sbjct: 410 LQGIFFDIYEGQITAILGHNGAGKSTLLNILSGLSVSTEGSATIYNTQLSEITDMEEIRK 469

Query: 276 VVAYVRNDTALCPTMSVEHTLRFHAALR--KPRNTHSHVKMGDRDRINLLIEELGLEQVR 333
            + +          ++V   LR  A ++  +P+     VK         +I EL ++ ++
Sbjct: 470 NIGFCPQFNFQFDFLTVRENLRVFAKIKGIQPKEVEQEVKR--------IIMELDMQSIQ 521

Query: 334 DTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIF 373
           D    +L+  + R+L +   +L D  +L+LD+PT  +D F
Sbjct: 522 DIIAKKLSGGQKRKLTLGIAILGDPQVLLLDEPTAGLDPF 561



 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 36/161 (22%), Positives = 74/161 (45%), Gaps = 10/161 (6%)

Query: 215  KSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVA----S 270
            K  + +  +SF VK GE+L +L       +  + ++ G  K  +G +V+ G   +     
Sbjct: 1217 KKKIAIRNVSFCVKKGEVLGLLGHNGAGKSTSIKMITGCTKPTAGVVVLQGSRASVRQQH 1276

Query: 271  STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLE 330
                K + Y   + +L P ++++  L  +AA++      + +       I+ L+E L L+
Sbjct: 1277 DNSLKFLGYCPQENSLWPKLTMKEHLELYAAVKGLGKEDAALS------ISRLVEALKLQ 1330

Query: 331  QVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
            +     V  L+    R+L     +L + ++++LD+P   MD
Sbjct: 1331 EQLKAPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPFTGMD 1371


>AY247065-1|AAO72161.1| 1543|Homo sapiens ATP-binding cassette
           sub-family A member 10 protein.
          Length = 1543

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 38/160 (23%), Positives = 75/160 (46%), Gaps = 14/160 (8%)

Query: 220 VSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST----LRK 275
           + G+ F++  G+I A+L       + LL++L+G+     G   I    ++  T    +RK
Sbjct: 410 LQGIFFDIYEGQITAILGHNGAGKSTLLNILSGLSVSTEGSATIYNTQLSEITDMEEIRK 469

Query: 276 VVAYVRNDTALCPTMSVEHTLRFHAALR--KPRNTHSHVKMGDRDRINLLIEELGLEQVR 333
            + +          ++V   LR  A ++  +P+     VK         +I EL ++ ++
Sbjct: 470 NIGFCPQFNFQFDFLTVRENLRVFAKIKGIQPKEVEQEVKR--------IIMELDMQSIQ 521

Query: 334 DTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIF 373
           D    +L+  + R+L +   +L D  +L+LD+PT  +D F
Sbjct: 522 DIIAKKLSGGQKRKLTLGIAILGDPQVLLLDEPTAGLDPF 561



 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 36/161 (22%), Positives = 74/161 (45%), Gaps = 10/161 (6%)

Query: 215  KSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVA----S 270
            K  + +  +SF VK GE+L +L       +  + ++ G  K  +G +V+ G   +     
Sbjct: 1217 KKKIAIRNVSFCVKKGEVLGLLGHNGAGKSTSIKMITGCTKPTAGVVVLQGSRASVRQQH 1276

Query: 271  STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLE 330
                K + Y   + +L P ++++  L  +AA++      + +       I+ L+E L L+
Sbjct: 1277 DNSLKFLGYCPQENSLWPKLTMKEHLELYAAVKGLGKEDAALS------ISRLVEALKLQ 1330

Query: 331  QVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
            +     V  L+    R+L     +L + ++++LD+P   MD
Sbjct: 1331 EQLKAPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPFTGMD 1371


>AY028900-1|AAK30025.1| 1543|Homo sapiens ATP-binding cassette A10
           protein.
          Length = 1543

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 38/160 (23%), Positives = 75/160 (46%), Gaps = 14/160 (8%)

Query: 220 VSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST----LRK 275
           + G+ F++  G+I A+L       + LL++L+G+     G   I    ++  T    +RK
Sbjct: 410 LQGIFFDIYEGQITAILGHNGAGKSTLLNILSGLSVSTEGSATIYNTQLSEITDMEEIRK 469

Query: 276 VVAYVRNDTALCPTMSVEHTLRFHAALR--KPRNTHSHVKMGDRDRINLLIEELGLEQVR 333
            + +          ++V   LR  A ++  +P+     VK         +I EL ++ ++
Sbjct: 470 NIGFCPQFNFQFDFLTVRENLRVFAKIKGIQPKEVEQEVKR--------IIMELDMQSIQ 521

Query: 334 DTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIF 373
           D    +L+  + R+L +   +L D  +L+LD+PT  +D F
Sbjct: 522 DIIAKKLSGGQKRKLTLGIAILGDPQVLLLDEPTAGLDPF 561



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 39/178 (21%), Positives = 79/178 (44%), Gaps = 11/178 (6%)

Query: 198  IYPNYYVNSLEITSPENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKL 257
            ++  YY       S   K  + +  +SF VK GE+L +L       +  + ++ G  K  
Sbjct: 1201 LHKEYYETKKSCFSTRKKK-IAIRNVSFCVKKGEVLGLLGHNGAGKSTSIKMITGCTKPT 1259

Query: 258  SGDIVINGQPVA----SSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVK 313
            +G +V+ G   +         K + Y   + +L P ++++  L  +AA++      + + 
Sbjct: 1260 AGVVVLQGSRASVRQQHDNSLKFLGYCPQENSLWPKLTMKEHLELYAAVKGLGKEDAALS 1319

Query: 314  MGDRDRINLLIEELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
                  I+ L+E L L++     V  L+    R+L     +L + ++++LD+P   MD
Sbjct: 1320 ------ISRLVEALKLQEQLKAPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPFTGMD 1371


>AB210044-1|BAE06126.1| 1708|Homo sapiens ABCA3 variant protein
            protein.
          Length = 1708

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 53/218 (24%), Positives = 92/218 (42%), Gaps = 9/218 (4%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST--LRK 275
            L V  LS  V+ GE   +L       T    +L G     SGD  + G  ++S    +R+
Sbjct: 1401 LAVDRLSLAVQKGECFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVGGHRISSDVGKVRQ 1460

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDT 335
             + Y     AL   M+    L  +A LR     H    + +  R  LL+E    + VR  
Sbjct: 1461 RIGYCPQFDALLDHMTGREMLVMYARLRGIPERHIGACVENTLR-GLLLEPHANKLVRTY 1519

Query: 336  NVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMS 395
            + G       R+L+    L+ + A++ LD+P+  MD      L + +     +G+ +I++
Sbjct: 1520 SGGNK-----RKLSTGIALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKAIIIT 1574

Query: 396  LHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSS 433
             H    E  A+ T++ ++  G+    G  + +   F S
Sbjct: 1575 SH-SMEECEALCTRLAIMVQGQFKCLGSPQHLKSKFGS 1611



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 44/186 (23%), Positives = 80/186 (43%), Gaps = 9/186 (4%)

Query: 214 NKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST- 272
           NK    V  L+  +  G+I  +L       T  L +L G+    SG   I+G  ++    
Sbjct: 547 NKDRAAVRDLNLNLYEGQITVLLGHNGAGKTTTLSMLTGLFPPTSGRAYISGYEISQDMV 606

Query: 273 -LRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQ 331
            +RK +        L   ++V   L F+A L+      S  K  +   +  ++  +GLE 
Sbjct: 607 QIRKSLGLCPQHDILFDNLTVAEHLYFYAQLKGL----SRQKCPEE--VKQMLHIIGLED 660

Query: 332 VRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRV 391
             ++    L+    R+L++   L+    +LILD+PT  MD      + + L+   S  R 
Sbjct: 661 KWNSRSRFLSGGMRRKLSIGIALIAGSKVLILDEPTSGMDAISRRAIWDLLQRQKS-DRT 719

Query: 392 VIMSLH 397
           ++++ H
Sbjct: 720 IVLTTH 725


>AB070929-1|BAB86781.1| 1704|Homo sapiens lamellar body membrane
            specific ATP-binding cassette protein protein.
          Length = 1704

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 53/218 (24%), Positives = 92/218 (42%), Gaps = 9/218 (4%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST--LRK 275
            L V  LS  V+ GE   +L       T    +L G     SGD  + G  ++S    +R+
Sbjct: 1397 LAVDRLSLAVQKGECFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVGGHRISSDVGKVRQ 1456

Query: 276  VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDT 335
             + Y     AL   M+    L  +A LR     H    + +  R  LL+E    + VR  
Sbjct: 1457 RIGYCPQFDALLDHMTGREMLVMYARLRGIPERHIGACVENTLR-GLLLEPHANKLVRTY 1515

Query: 336  NVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMS 395
            + G       R+L+    L+ + A++ LD+P+  MD      L + +     +G+ +I++
Sbjct: 1516 SGGNK-----RKLSTGIALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKAIIIT 1570

Query: 396  LHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLPYFSS 433
             H    E  A+ T++ ++  G+    G  + +   F S
Sbjct: 1571 SH-SMEECEALCTRLAIMVQGQFKCLGSPQHLKSKFGS 1607



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 44/186 (23%), Positives = 80/186 (43%), Gaps = 9/186 (4%)

Query: 214 NKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST- 272
           NK    V  L+  +  G+I  +L       T  L +L G+    SG   I+G  ++    
Sbjct: 543 NKDRAAVRDLNLNLYEGQITVLLGHNGAGKTTTLSMLTGLFPPTSGRAYISGYEISQDMV 602

Query: 273 -LRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQ 331
            +RK +        L   ++V   L F+A L+      S  K  +   +  ++  +GLE 
Sbjct: 603 QIRKSLGLCPQHDILFDNLTVAEHLYFYAQLKGL----SRQKCPEE--VKQMLHIIGLED 656

Query: 332 VRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRV 391
             ++    L+    R+L++   L+    +LILD+PT  MD      + + L+   S  R 
Sbjct: 657 KWNSRSRFLSGGMRRKLSIGIALIAGSKVLILDEPTSGMDAISRRAIWDLLQRQKS-DRT 715

Query: 392 VIMSLH 397
           ++++ H
Sbjct: 716 IVLTTH 721


>AF328787-1|AAK00959.1| 2146|Homo sapiens ABC transporter member 7
            protein.
          Length = 2146

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 57/225 (25%), Positives = 96/225 (42%), Gaps = 11/225 (4%)

Query: 200  PNYYVNSLEITSPENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSG 259
            P   V SLE   P +     + GLS +   G I A L       T  L +L+G+     G
Sbjct: 805  PGVSVRSLEKRFPGSPQP-ALRGLSLDFYQGHITAFLGHNGAGKTTTLSILSGLFPPSGG 863

Query: 260  DIVINGQPVASS--TLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDR 317
               I G  V SS   +R  +        L   ++V+  + F+  L+      + V   ++
Sbjct: 864  SAFILGHDVRSSMAAIRPHLGVCPQYNVLFDMLTVDEHVWFYGRLK---GLSAAVVGPEQ 920

Query: 318  DRINLLIEELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFF 377
            DR   L++++GL   +      L+    R+L+VA   +    ++ILD+PT  +D      
Sbjct: 921  DR---LLQDVGLVSKQSVQTRHLSGGMQRKLSVAIAFVGGSQVVILDEPTAGVDPASRRG 977

Query: 378  LVEYLRNWASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSG 422
            + E L  +   GR +I+S H    E   +  +V +++ GR    G
Sbjct: 978  IWELLLKYRE-GRTLILSTH-HLDEAELLGDRVAVVAGGRLCCCG 1020



 Score = 40.3 bits (90), Expect = 0.027
 Identities = 48/200 (24%), Positives = 74/200 (37%), Gaps = 9/200 (4%)

Query: 220  VSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS--STLRKVV 277
            V  L   +  GE   +L       T    ++ G      G+ V+ G  VA   S     +
Sbjct: 1810 VDRLCLGIPPGECFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSM 1869

Query: 278  AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
             Y     A+   ++    L   A LR           G        +  LGL    D   
Sbjct: 1870 GYCPQSDAIFELLTGREHLELLARLRGVPEAQVAQTAGSG------LARLGLSWYADRPA 1923

Query: 338  GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
            G  +    R+L  A  L+ D A++ LD+PT  MD     FL   L      GR V+++ H
Sbjct: 1924 GTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLAVVREGRSVMLTSH 1983

Query: 398  PPTYEIFAMLTKVVLISAGR 417
                E  A+ +++ ++  GR
Sbjct: 1984 -SMEECEALCSRLAIMVNGR 2002


>AF311102-1|AAN04657.1| 2146|Homo sapiens ABC transporter ABCA7
            protein.
          Length = 2146

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 57/225 (25%), Positives = 96/225 (42%), Gaps = 11/225 (4%)

Query: 200  PNYYVNSLEITSPENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSG 259
            P   V SLE   P +     + GLS +   G I A L       T  L +L+G+     G
Sbjct: 805  PGVSVRSLEKRFPGSPQP-ALRGLSLDFYQGHITAFLGHNGAGKTTTLSILSGLFPPSGG 863

Query: 260  DIVINGQPVASS--TLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDR 317
               I G  V SS   +R  +        L   ++V+  + F+  L+      + V   ++
Sbjct: 864  SAFILGHDVRSSMAAIRPHLGVCPQYNVLFDMLTVDEHVWFYGRLK---GLSAAVVGPEQ 920

Query: 318  DRINLLIEELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFF 377
            DR   L++++GL   +      L+    R+L+VA   +    ++ILD+PT  +D      
Sbjct: 921  DR---LLQDVGLVSKQSVQTRHLSGGMQRKLSVAIAFVGGSQVVILDEPTAGVDPASRRG 977

Query: 378  LVEYLRNWASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSG 422
            + E L  +   GR +I+S H    E   +  +V +++ GR    G
Sbjct: 978  IWELLLKYRE-GRTLILSTH-HLDEAELLGDRVAVVAGGRLCCCG 1020



 Score = 40.3 bits (90), Expect = 0.027
 Identities = 48/200 (24%), Positives = 74/200 (37%), Gaps = 9/200 (4%)

Query: 220  VSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS--STLRKVV 277
            V  L   +  GE   +L       T    ++ G      G+ V+ G  VA   S     +
Sbjct: 1810 VDRLCLGIPPGECFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSM 1869

Query: 278  AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
             Y     A+   ++    L   A LR           G        +  LGL    D   
Sbjct: 1870 GYCPQSDAIFELLTGREHLELLARLRGVPEAQVAQTAGSG------LARLGLSWYADRPA 1923

Query: 338  GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
            G  +    R+L  A  L+ D A++ LD+PT  MD     FL   L      GR V+++ H
Sbjct: 1924 GTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLAVVREGRSVMLTSH 1983

Query: 398  PPTYEIFAMLTKVVLISAGR 417
                E  A+ +++ ++  GR
Sbjct: 1984 -SMEECEALCSRLAIMVNGR 2002


>AF250238-1|AAF85794.1| 2146|Homo sapiens macrophage ABC transporter
            protein.
          Length = 2146

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 57/225 (25%), Positives = 96/225 (42%), Gaps = 11/225 (4%)

Query: 200  PNYYVNSLEITSPENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSG 259
            P   V SLE   P +     + GLS +   G I A L       T  L +L+G+     G
Sbjct: 805  PGVSVRSLEKRFPGSPQP-ALRGLSLDFYQGHITAFLGHNGAGKTTTLSILSGLFPPSGG 863

Query: 260  DIVINGQPVASS--TLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDR 317
               I G  V SS   +R  +        L   ++V+  + F+  L+      + V   ++
Sbjct: 864  SAFILGHDVRSSMAAIRPHLGVCPQYNVLFDMLTVDEHVWFYGRLK---GLSAAVVGPEQ 920

Query: 318  DRINLLIEELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFF 377
            DR   L++++GL   +      L+    R+L+VA   +    ++ILD+PT  +D      
Sbjct: 921  DR---LLQDVGLVSKQSVQTRHLSGGMQRKLSVAIAFVGGSQVVILDEPTAGVDPASRRG 977

Query: 378  LVEYLRNWASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSG 422
            + E L  +   GR +I+S H    E   +  +V +++ GR    G
Sbjct: 978  IWELLLKYRE-GRTLILSTH-HLDEAELLGDRVAVVAGGRLCCCG 1020



 Score = 40.3 bits (90), Expect = 0.027
 Identities = 48/200 (24%), Positives = 74/200 (37%), Gaps = 9/200 (4%)

Query: 220  VSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS--STLRKVV 277
            V  L   +  GE   +L       T    ++ G      G+ V+ G  VA   S     +
Sbjct: 1810 VDRLCLGIPPGECFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSM 1869

Query: 278  AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
             Y     A+   ++    L   A LR           G        +  LGL    D   
Sbjct: 1870 GYCPQSDAIFELLTGREHLELLARLRGVPEAQVAQTAGSG------LARLGLSWYADRPA 1923

Query: 338  GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
            G  +    R+L  A  L+ D A++ LD+PT  MD     FL   L      GR V+++ H
Sbjct: 1924 GTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLAVVREGRSVMLTSH 1983

Query: 398  PPTYEIFAMLTKVVLISAGR 417
                E  A+ +++ ++  GR
Sbjct: 1984 -SMEECEALCSRLAIMVNGR 2002


>AB055390-1|BAB62294.1| 2008|Homo sapiens ABCA-SSN protein.
          Length = 2008

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 57/225 (25%), Positives = 96/225 (42%), Gaps = 11/225 (4%)

Query: 200 PNYYVNSLEITSPENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSG 259
           P   V SLE   P +     + GLS +   G I A L       T  L +L+G+     G
Sbjct: 667 PGVSVRSLEKRFPGSPQP-ALRGLSLDFYQGHITAFLGHNGAGKTTTLSILSGLFPPSGG 725

Query: 260 DIVINGQPVASS--TLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDR 317
              I G  V SS   +R  +        L   ++V+  + F+  L+      + V   ++
Sbjct: 726 SAFILGHDVRSSMAAIRPHLGVCPQYNVLFDMLTVDEHVWFYGRLK---GLSAAVVGPEQ 782

Query: 318 DRINLLIEELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFF 377
           DR   L++++GL   +      L+    R+L+VA   +    ++ILD+PT  +D      
Sbjct: 783 DR---LLQDVGLVSKQSVQTRHLSGGMQRKLSVAIAFVGGSQVVILDEPTAGVDPASRRG 839

Query: 378 LVEYLRNWASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSG 422
           + E L  +   GR +I+S H    E   +  +V +++ GR    G
Sbjct: 840 IWELLLKYRE-GRTLILSTH-HLDEAELLGDRVAVVAGGRLCCCG 882



 Score = 40.3 bits (90), Expect = 0.027
 Identities = 48/200 (24%), Positives = 74/200 (37%), Gaps = 9/200 (4%)

Query: 220  VSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS--STLRKVV 277
            V  L   +  GE   +L       T    ++ G      G+ V+ G  VA   S     +
Sbjct: 1672 VDRLCLGIPPGECFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSM 1731

Query: 278  AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
             Y     A+   ++    L   A LR           G        +  LGL    D   
Sbjct: 1732 GYCPQSDAIFELLTGREHLELLARLRGVPEAQVAQTAGSG------LARLGLSWYADRPA 1785

Query: 338  GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
            G  +    R+L  A  L+ D A++ LD+PT  MD     FL   L      GR V+++ H
Sbjct: 1786 GTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLAVVREGRSVMLTSH 1845

Query: 398  PPTYEIFAMLTKVVLISAGR 417
                E  A+ +++ ++  GR
Sbjct: 1846 -SMEECEALCSRLAIMVNGR 1864


>AK128570-1|BAC87504.1|  851|Homo sapiens protein ( Homo sapiens
           cDNA FLJ46729 fis, clone TRACH3019370, weakly  similar
           to ATP-binding cassette, sub-family A, member 1. ).
          Length = 851

 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 45/193 (23%), Positives = 81/193 (41%), Gaps = 14/193 (7%)

Query: 204 VNSLEITSPENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVI 263
           V  + +T        VV  LS      +I A+L T     T ++ +L G+    SG I+I
Sbjct: 597 VTLVSVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIII 656

Query: 264 NGQPVASSTLRKVVAYVRNDTALCPTMSV---EHTLRFHAALRKPRNTHSHVKMGDRDRI 320
           NG+      L+  ++ VR +  +CP   +     T+R H  L          K     ++
Sbjct: 657 NGK-----NLQTDLSRVRMELGVCPQQDILLDNLTVREHLLLFASIKAPQWTKKELHQQV 711

Query: 321 NLLIEELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMD------IFD 374
           N  ++++ L Q +      L+    R+L++    +     ++LD+PT  +D      ++D
Sbjct: 712 NQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWD 771

Query: 375 TFFLVEYLRNWAS 387
                   R+WAS
Sbjct: 772 ILLKYREGRHWAS 784


>AY219711-1|AAP21093.1| 2595|Homo sapiens ABCA12 transporter subfamily
            A protein.
          Length = 2595

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 46/207 (22%), Positives = 90/207 (43%), Gaps = 10/207 (4%)

Query: 214  NKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTL 273
            +K  + V+ +S  +  GE   +L       T +  +L G     SG+I+I  +  +   +
Sbjct: 2267 HKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHV 2326

Query: 274  ---RKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLE 330
                 +V Y   + AL   ++VE  L F+A +      H   +   ++ ++ L+  L L 
Sbjct: 2327 DSHSSLVGYCPQEDALDDLVTVEEHLYFYARV------HGIPEKDIKETVHKLLRRLHLM 2380

Query: 331  QVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGR 390
              +D      +    R+L+ A  L+   +IL+LD+P+  MD      L + +        
Sbjct: 2381 PFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKC 2440

Query: 391  VVIMSLHPPTYEIFAMLTKVVLISAGR 417
             VI++ H    E  A+ T++ ++  G+
Sbjct: 2441 SVILTSH-SMEECEALCTRLAIMVNGK 2466



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 38/184 (20%), Positives = 81/184 (44%), Gaps = 7/184 (3%)

Query: 216  STLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASS--TL 273
            S + V  L+     G I ++L       T  + +L G+    +G I + G+ + +   T+
Sbjct: 1357 SKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTV 1416

Query: 274  RKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVR 333
            RK +        L   ++ +  L  + +++ P  T   +     + +   +++ GL   R
Sbjct: 1417 RKNMGVCMQHDVLFSYLTTKEHLLLYGSIKVPHWTKKQL----HEEVKRTLKDTGLYSHR 1472

Query: 334  DTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVI 393
               VG L+    R+L+++  L+    ++ILD+P+  +D      + + +     T R +I
Sbjct: 1473 HKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISK-NKTARTII 1531

Query: 394  MSLH 397
            +S H
Sbjct: 1532 LSTH 1535


>AY033486-1|AAK54355.1| 2277|Homo sapiens ATP-binding cassette
            transporter family A member 12 protein.
          Length = 2277

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 46/207 (22%), Positives = 90/207 (43%), Gaps = 10/207 (4%)

Query: 214  NKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTL 273
            +K  + V+ +S  +  GE   +L       T +  +L G     SG+I+I  +  +   +
Sbjct: 1949 HKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHV 2008

Query: 274  ---RKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLE 330
                 +V Y   + AL   ++VE  L F+A +      H   +   ++ ++ L+  L L 
Sbjct: 2009 DSHSSLVGYCPQEDALDDLVTVEEHLYFYARV------HGIPEKDIKETVHKLLRRLHLM 2062

Query: 331  QVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGR 390
              +D      +    R+L+ A  L+   +IL+LD+P+  MD      L + +        
Sbjct: 2063 PFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKC 2122

Query: 391  VVIMSLHPPTYEIFAMLTKVVLISAGR 417
             VI++ H    E  A+ T++ ++  G+
Sbjct: 2123 SVILTSH-SMEECEALCTRLAIMVNGK 2148



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 38/184 (20%), Positives = 81/184 (44%), Gaps = 7/184 (3%)

Query: 216  STLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASS--TL 273
            S + V  L+     G I ++L       T  + +L G+    +G I + G+ + +   T+
Sbjct: 1039 SKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTV 1098

Query: 274  RKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVR 333
            RK +        L   ++ +  L  + +++ P  T   +     + +   +++ GL   R
Sbjct: 1099 RKNMGVCMQHDVLFSYLTTKEHLLLYGSIKVPHWTKKQL----HEEVKRTLKDTGLYSHR 1154

Query: 334  DTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVI 393
               VG L+    R+L+++  L+    ++ILD+P+  +D      + + +     T R +I
Sbjct: 1155 HKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISK-NKTARTII 1213

Query: 394  MSLH 397
            +S H
Sbjct: 1214 LSTH 1217


>AF418105-1|AAN40735.1| 2347|Homo sapiens ATP-binding cassette
            transporter family A member 12 protein.
          Length = 2347

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 46/207 (22%), Positives = 90/207 (43%), Gaps = 10/207 (4%)

Query: 214  NKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTL 273
            +K  + V+ +S  +  GE   +L       T +  +L G     SG+I+I  +  +   +
Sbjct: 2019 HKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHV 2078

Query: 274  ---RKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLE 330
                 +V Y   + AL   ++VE  L F+A +      H   +   ++ ++ L+  L L 
Sbjct: 2079 DSHSSLVGYCPQEDALDDLVTVEEHLYFYARV------HGIPEKDIKETVHKLLRRLHLM 2132

Query: 331  QVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGR 390
              +D      +    R+L+ A  L+   +IL+LD+P+  MD      L + +        
Sbjct: 2133 PFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKC 2192

Query: 391  VVIMSLHPPTYEIFAMLTKVVLISAGR 417
             VI++ H    E  A+ T++ ++  G+
Sbjct: 2193 SVILTSH-SMEECEALCTRLAIMVNGK 2218



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 38/184 (20%), Positives = 81/184 (44%), Gaps = 7/184 (3%)

Query: 216  STLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASS--TL 273
            S + V  L+     G I ++L       T  + +L G+    +G I + G+ + +   T+
Sbjct: 1109 SKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTV 1168

Query: 274  RKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVR 333
            RK +        L   ++ +  L  + +++ P  T   +     + +   +++ GL   R
Sbjct: 1169 RKNMGVCMQHDVLFSYLTTKEHLLLYGSIKVPHWTKKQL----HEEVKRTLKDTGLYSHR 1224

Query: 334  DTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVI 393
               VG L+    R+L+++  L+    ++ILD+P+  +D      + + +     T R +I
Sbjct: 1225 HKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISK-NKTARTII 1283

Query: 394  MSLH 397
            +S H
Sbjct: 1284 LSTH 1287


>AB177854-1|BAD66832.1| 1440|Homo sapiens KIAA1062 splice variant 1
           protein.
          Length = 1440

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 47/207 (22%), Positives = 92/207 (44%), Gaps = 10/207 (4%)

Query: 218 LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST--LRK 275
           L ++ LS  +   ++++ L       T  + +L G+    SG   I G  + +    +RK
Sbjct: 355 LALNKLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIRK 414

Query: 276 VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDT 335
            +        L   ++VE  L F++ L+      S  +   R  ++ +IE+L L   R +
Sbjct: 415 NLGMCPQHNVLFDRLTVEEHLWFYSRLK------SMAQEEIRREMDKMIEDLELSNKRHS 468

Query: 336 NVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMS 395
            V  L+    R+L+VA   +     +ILD+PT  +D +    + + +  +   GR +++S
Sbjct: 469 LVQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKY-KPGRTILLS 527

Query: 396 LHPPTYEIFAMLTKVVLISAGRTMFSG 422
            H    E   +  ++ +IS G+    G
Sbjct: 528 THHMD-EADLLGDRIAIISHGKLKCCG 553


>AC072062-1|AAY24276.1| 2413|Homo sapiens unknown protein.
          Length = 2413

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 38/184 (20%), Positives = 81/184 (44%), Gaps = 7/184 (3%)

Query: 216  STLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASS--TL 273
            S + V  L+     G I ++L       T  + +L G+    +G I + G+ + +   T+
Sbjct: 1357 SKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTV 1416

Query: 274  RKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVR 333
            RK +        L   ++ +  L  + +++ P  T   +     + +   +++ GL   R
Sbjct: 1417 RKNMGVCMQHDVLFSYLTTKEHLLLYGSIKVPHWTKKQL----HEEVKRTLKDTGLYSHR 1472

Query: 334  DTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVI 393
               VG L+    R+L+++  L+    ++ILD+P+  +D      + + +     T R +I
Sbjct: 1473 HKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISK-NKTARTII 1531

Query: 394  MSLH 397
            +S H
Sbjct: 1532 LSTH 1535



 Score = 35.9 bits (79), Expect = 0.58
 Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 9/153 (5%)

Query: 214  NKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASSTL 273
            +K  + V+ +S  +  GE   +L       T +  +L G     SG+I+I  +  +   +
Sbjct: 2267 HKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHV 2326

Query: 274  ---RKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLE 330
                 +V Y   + AL   ++VE  L F+A        H   +   ++ ++ L+  L L 
Sbjct: 2327 DSHSSLVGYCPQEDALDDLVTVEEHLYFYA------RVHGIPEKDIKETVHKLLRRLHLM 2380

Query: 331  QVRDTNVGRLTRSEIRRLNVACQLLLDMAILIL 363
              +D      +    R+L+ A  L+   +IL+L
Sbjct: 2381 PFKDRATSMCSYGTKRKLSTALALIGKPSILLL 2413


>BC051320-1|AAH51320.1|  419|Homo sapiens ABCA10 protein protein.
          Length = 419

 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 36/161 (22%), Positives = 74/161 (45%), Gaps = 10/161 (6%)

Query: 215 KSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVA----S 270
           K  + +  +SF VK GE+L +L       +  + ++ G  K  +G +V+ G   +     
Sbjct: 93  KKKIAIRNVSFCVKKGEVLGLLGHNGAGKSTSIKMITGCTKPTAGVVVLQGSRASVRQQH 152

Query: 271 STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLE 330
               K + Y   + +L P ++++  L  +AA++      + +       I+ L+E L L+
Sbjct: 153 DNSLKFLGYCPQENSLWPKLTMKEHLELYAAVKGLGKEDAALS------ISRLVEALKLQ 206

Query: 331 QVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
           +     V  L+    R+L     +L + ++++LD+P   MD
Sbjct: 207 EQLKAPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPFTGMD 247


>AF165306-1|AAD49852.1|  849|Homo sapiens ATP cassette binding
           transporter 1 protein.
          Length = 849

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 44/172 (25%), Positives = 84/172 (48%), Gaps = 11/172 (6%)

Query: 249 VLAGVRKKLSGDIVINGQPVAS--STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPR 306
           +L G+    SG   I G+ + S  ST+R+ +        L   ++VE  + F+A L+   
Sbjct: 2   ILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVEEHIWFYARLKGL- 60

Query: 307 NTHSHVKMGDRDRINLLIEELGLEQVR-DTNVGRLTRSEIRRLNVACQLLLDMAILILDQ 365
            +  HVK  + +++ L   ++GL   +  +   +L+    R+L+VA   +    ++ILD+
Sbjct: 61  -SEKHVK-AEMEQMAL---DVGLPSSKLKSKTSQLSGGMQRKLSVALAFVGGSKVVILDE 115

Query: 366 PTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAMLTKVVLISAGR 417
           PT  +D +    + E L  +   GR +I+S H    E   +  ++ +IS G+
Sbjct: 116 PTAGVDPYSRRGIWELLLKYRQ-GRTIILSTHHMD-EADVLGDRIAIISHGK 165


>BX640746-1|CAE45856.1|  431|Homo sapiens hypothetical protein
           protein.
          Length = 431

 Score = 44.8 bits (101), Expect = 0.001
 Identities = 42/180 (23%), Positives = 81/180 (45%), Gaps = 13/180 (7%)

Query: 223 LSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST----LRKVVA 278
           LSF++  G+I A+L  +    + L+++L G+     G   I G  V+        RK++ 
Sbjct: 171 LSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIG 230

Query: 279 YVRNDTALCPTMSVEHTLRFHAALRK-PRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
                      ++VE  L   A+++  P N            +  ++ +L ++ ++D   
Sbjct: 231 ICPQLDIHFDVLTVEENLSILASIKGIPANNIIQ-------EVQKVLLDLDMQTIKDNQA 283

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
            +L+  + R+L++   +L +  IL+LD+PT  MD      +V  L  +    RV + S H
Sbjct: 284 KKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSR-HIVWNLLKYRKANRVTVFSTH 342


>AY028897-1|AAK30022.1| 1642|Homo sapiens ATP-binding cassette A5
           protein.
          Length = 1642

 Score = 44.8 bits (101), Expect = 0.001
 Identities = 42/180 (23%), Positives = 81/180 (45%), Gaps = 13/180 (7%)

Query: 223 LSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST----LRKVVA 278
           LSF++  G+I A+L  +    + L+++L G+     G   I G  V+        RK++ 
Sbjct: 500 LSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIG 559

Query: 279 YVRNDTALCPTMSVEHTLRFHAALRK-PRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
                      ++VE  L   A+++  P N            +  ++ +L ++ ++D   
Sbjct: 560 ICPQLDIHFDVLTVEENLSILASIKGIPANNIIQ-------EVQKVLLDLDMQTIKDNQA 612

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
            +L+  + R+L++   +L +  IL+LD+PT  MD      +V  L  +    RV + S H
Sbjct: 613 KKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSR-HIVWNLLKYRKANRVTVFSTH 671



 Score = 35.1 bits (77), Expect = 1.0
 Identities = 35/152 (23%), Positives = 68/152 (44%), Gaps = 9/152 (5%)

Query: 223  LSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVI---NGQPVASSTLRKVVAY 279
            +SF VK GEIL +L       + ++++L G  +  SG + +   + +        K + Y
Sbjct: 1319 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDDSLKCMGY 1378

Query: 280  VRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGR 339
                  L P  +++     + A++    + S +K    + I+ +   L L++     V +
Sbjct: 1379 CPQINPLWPDTTLQEHFEIYGAVK--GMSASDMK----EVISRITHALDLKEHLQKTVKK 1432

Query: 340  LTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
            L     R+L  A  +L +  I +LD+P+  MD
Sbjct: 1433 LPAGIKRKLCFALSMLGNPQITLLDEPSTGMD 1464


>AJ512612-1|CAD54757.1|  925|Homo sapiens ABCA5 transporter protein.
          Length = 925

 Score = 44.8 bits (101), Expect = 0.001
 Identities = 42/180 (23%), Positives = 81/180 (45%), Gaps = 13/180 (7%)

Query: 223 LSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST----LRKVVA 278
           LSF++  G+I A+L  +    + L+++L G+     G   I G  V+        RK++ 
Sbjct: 500 LSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIG 559

Query: 279 YVRNDTALCPTMSVEHTLRFHAALRK-PRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
                      ++VE  L   A+++  P N            +  ++ +L ++ ++D   
Sbjct: 560 ICPQLDIHFDVLTVEENLSILASIKGIPANNIIQ-------EVQKVLLDLDMQTIKDNQA 612

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
            +L+  + R+L++   +L +  IL+LD+PT  MD      +V  L  +    RV + S H
Sbjct: 613 KKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSR-HIVWNLLKYRKANRVTVFSTH 671


>AJ275973-1|CAB93535.3| 1642|Homo sapiens ATP-binding cassette
           protein protein.
          Length = 1642

 Score = 44.8 bits (101), Expect = 0.001
 Identities = 42/180 (23%), Positives = 81/180 (45%), Gaps = 13/180 (7%)

Query: 223 LSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST----LRKVVA 278
           LSF++  G+I A+L  +    + L+++L G+     G   I G  V+        RK++ 
Sbjct: 500 LSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIG 559

Query: 279 YVRNDTALCPTMSVEHTLRFHAALRK-PRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
                      ++VE  L   A+++  P N            +  ++ +L ++ ++D   
Sbjct: 560 ICPQLDIHFDVLTVEENLSILASIKGIPANNIIQ-------EVQKVLLDLDMQTIKDNQA 612

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
            +L+  + R+L++   +L +  IL+LD+PT  MD      +V  L  +    RV + S H
Sbjct: 613 KKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSR-HIVWNLLKYRKANRVTVFSTH 671



 Score = 36.7 bits (81), Expect = 0.33
 Identities = 38/152 (25%), Positives = 68/152 (44%), Gaps = 9/152 (5%)

Query: 223  LSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASS---TLRKVVAY 279
            +SF VK GEIL +L       + ++++L G  +  SG I +      SS      K + Y
Sbjct: 1319 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQIFLGDYSSESSEDDDSLKCMGY 1378

Query: 280  VRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGR 339
                  L P  +++     + A++    + S +K    + I+ +   L L++     V +
Sbjct: 1379 CPQINPLWPDTTLQEHFEIYGAVK--GMSASDMK----EVISRITHALDLKEHLQKTVKK 1432

Query: 340  LTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
            L     R+L  A  +L +  I +LD+P+  MD
Sbjct: 1433 LPAGIKRKLCFALSMLGNPQITLLDEPSTGMD 1464


>BT009918-1|AAP88920.1|  753|Homo sapiens ATP-binding cassette,
           sub-family B (MDR/TAP), member 7 protein.
          Length = 753

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 41/161 (25%), Positives = 76/161 (47%), Gaps = 15/161 (9%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVING---QPVASSTLRK 275
           V+SG+SFEV  G+ +A++  +    + ++ +L    +   G I + G   Q V+  +LR+
Sbjct: 488 VLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRR 547

Query: 276 VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKM-GDRDRINLLIEELGLEQVRD 334
            V  V  D  L    ++ + L +      P   ++  K+ G  D I      L +    D
Sbjct: 548 AVGVVPQDAVLFHN-TIYYNLLYGNISASPEEVYAVAKLAGLHDAI------LRMPHGYD 600

Query: 335 TNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
           T VG    +L+  E +R+ +A  +L D  +++ D+ T  +D
Sbjct: 601 TQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLD 641


>BC006323-1|AAH06323.1|  753|Homo sapiens ATP-binding cassette,
           sub-family B (MDR/TAP), member 7 protein.
          Length = 753

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 41/161 (25%), Positives = 76/161 (47%), Gaps = 15/161 (9%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVING---QPVASSTLRK 275
           V+SG+SFEV  G+ +A++  +    + ++ +L    +   G I + G   Q V+  +LR+
Sbjct: 488 VLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRR 547

Query: 276 VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKM-GDRDRINLLIEELGLEQVRD 334
            V  V  D  L    ++ + L +      P   ++  K+ G  D I      L +    D
Sbjct: 548 AVGVVPQDAVLFHN-TIYYNLLYGNISASPEEVYAVAKLAGLHDAI------LRMPHGYD 600

Query: 335 TNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
           T VG    +L+  E +R+ +A  +L D  +++ D+ T  +D
Sbjct: 601 TQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLD 641


>AL360179-2|CAH70565.1|  752|Homo sapiens ATP-binding cassette,
           sub-family B (MDR/TAP), member 7 protein.
          Length = 752

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 41/161 (25%), Positives = 76/161 (47%), Gaps = 15/161 (9%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVING---QPVASSTLRK 275
           V+SG+SFEV  G+ +A++  +    + ++ +L    +   G I + G   Q V+  +LR+
Sbjct: 487 VLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRR 546

Query: 276 VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKM-GDRDRINLLIEELGLEQVRD 334
            V  V  D  L    ++ + L +      P   ++  K+ G  D I      L +    D
Sbjct: 547 AVGVVPQDAVLFHN-TIYYNLLYGNISASPEEVYAVAKLAGLHDAI------LRMPHGYD 599

Query: 335 TNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
           T VG    +L+  E +R+ +A  +L D  +++ D+ T  +D
Sbjct: 600 TQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLD 640


>AL360179-1|CAH70564.1|  753|Homo sapiens ATP-binding cassette,
           sub-family B (MDR/TAP), member 7 protein.
          Length = 753

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 41/161 (25%), Positives = 76/161 (47%), Gaps = 15/161 (9%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVING---QPVASSTLRK 275
           V+SG+SFEV  G+ +A++  +    + ++ +L    +   G I + G   Q V+  +LR+
Sbjct: 488 VLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRR 547

Query: 276 VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKM-GDRDRINLLIEELGLEQVRD 334
            V  V  D  L    ++ + L +      P   ++  K+ G  D I      L +    D
Sbjct: 548 AVGVVPQDAVLFHN-TIYYNLLYGNISASPEEVYAVAKLAGLHDAI------LRMPHGYD 600

Query: 335 TNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
           T VG    +L+  E +R+ +A  +L D  +++ D+ T  +D
Sbjct: 601 TQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLD 641


>AL359545-2|CAI41573.1|  752|Homo sapiens ATP-binding cassette,
           sub-family B (MDR/TAP), member 7 protein.
          Length = 752

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 41/161 (25%), Positives = 76/161 (47%), Gaps = 15/161 (9%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVING---QPVASSTLRK 275
           V+SG+SFEV  G+ +A++  +    + ++ +L    +   G I + G   Q V+  +LR+
Sbjct: 487 VLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRR 546

Query: 276 VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKM-GDRDRINLLIEELGLEQVRD 334
            V  V  D  L    ++ + L +      P   ++  K+ G  D I      L +    D
Sbjct: 547 AVGVVPQDAVLFHN-TIYYNLLYGNISASPEEVYAVAKLAGLHDAI------LRMPHGYD 599

Query: 335 TNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
           T VG    +L+  E +R+ +A  +L D  +++ D+ T  +D
Sbjct: 600 TQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLD 640


>AL359545-1|CAI41574.1|  753|Homo sapiens ATP-binding cassette,
           sub-family B (MDR/TAP), member 7 protein.
          Length = 753

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 41/161 (25%), Positives = 76/161 (47%), Gaps = 15/161 (9%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVING---QPVASSTLRK 275
           V+SG+SFEV  G+ +A++  +    + ++ +L    +   G I + G   Q V+  +LR+
Sbjct: 488 VLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRR 547

Query: 276 VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKM-GDRDRINLLIEELGLEQVRD 334
            V  V  D  L    ++ + L +      P   ++  K+ G  D I      L +    D
Sbjct: 548 AVGVVPQDAVLFHN-TIYYNLLYGNISASPEEVYAVAKLAGLHDAI------LRMPHGYD 600

Query: 335 TNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
           T VG    +L+  E +R+ +A  +L D  +++ D+ T  +D
Sbjct: 601 TQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLD 641


>AF241887-1|AAK20173.1|  752|Homo sapiens ATP binding cassette 7
           protein.
          Length = 752

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 41/161 (25%), Positives = 76/161 (47%), Gaps = 15/161 (9%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVING---QPVASSTLRK 275
           V+SG+SFEV  G+ +A++  +    + ++ +L    +   G I + G   Q V+  +LR+
Sbjct: 487 VLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRR 546

Query: 276 VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKM-GDRDRINLLIEELGLEQVRD 334
            V  V  D  L    ++ + L +      P   ++  K+ G  D I      L +    D
Sbjct: 547 AVGVVPQDAVLFHN-TIYYNLLYGNISASPEEVYAVAKLAGLHDAI------LRMPHGYD 599

Query: 335 TNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
           T VG    +L+  E +R+ +A  +L D  +++ D+ T  +D
Sbjct: 600 TQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLD 640


>AF133659-1|AAD33045.1|  752|Homo sapiens ATP-binding cassette 7
           iron transporter protein.
          Length = 752

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 41/161 (25%), Positives = 76/161 (47%), Gaps = 15/161 (9%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVING---QPVASSTLRK 275
           V+SG+SFEV  G+ +A++  +    + ++ +L    +   G I + G   Q V+  +LR+
Sbjct: 487 VLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRR 546

Query: 276 VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKM-GDRDRINLLIEELGLEQVRD 334
            V  V  D  L    ++ + L +      P   ++  K+ G  D I      L +    D
Sbjct: 547 AVGVVPQDAVLFHN-TIYYNLLYGNISASPEEVYAVAKLAGLHDAI------LRMPHGYD 599

Query: 335 TNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
           T VG    +L+  E +R+ +A  +L D  +++ D+ T  +D
Sbjct: 600 TQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLD 640


>AB005289-1|BAA28861.1|  752|Homo sapiens ABC transporter 7 protein
           protein.
          Length = 752

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 41/161 (25%), Positives = 76/161 (47%), Gaps = 15/161 (9%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVING---QPVASSTLRK 275
           V+SG+SFEV  G+ +A++  +    + ++ +L    +   G I + G   Q V+  +LR+
Sbjct: 487 VLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRR 546

Query: 276 VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKM-GDRDRINLLIEELGLEQVRD 334
            V  V  D  L    ++ + L +      P   ++  K+ G  D I      L +    D
Sbjct: 547 AVGVVPQDAVLFHN-TIYYNLLYGNISASPEEVYAVAKLAGLHDAI------LRMPHGYD 599

Query: 335 TNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
           T VG    +L+  E +R+ +A  +L D  +++ D+ T  +D
Sbjct: 600 TQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLD 640


>AF078777-1|AAD47141.1|  748|Homo sapiens ABC transporter protein.
          Length = 748

 Score = 43.6 bits (98), Expect = 0.003
 Identities = 41/161 (25%), Positives = 76/161 (47%), Gaps = 15/161 (9%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVING---QPVASSTLRK 275
           V+SG+SFEV  G+ +A++  +    + ++ +L    +   G I + G   Q V+  +LR+
Sbjct: 483 VLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLVSLRR 542

Query: 276 VVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKM-GDRDRINLLIEELGLEQVRD 334
            V  V  D  L    ++ + L +      P   ++  K+ G  D I      L +    D
Sbjct: 543 AVGVVPQDAVLFHN-TIYYNLLYGNISASPEEVYAVAKLAGLHDAI------LRMPHGYD 595

Query: 335 TNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
           T VG    +L+  E +R+ +A  +L D  +++ D+ T  +D
Sbjct: 596 TQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLD 636


>BC131732-1|AAI31733.1| 1503|Homo sapiens ATP-binding cassette,
            sub-family C (CFTR/MRP), member 6 protein.
          Length = 1503

 Score = 41.1 bits (92), Expect = 0.016
 Identities = 44/183 (24%), Positives = 83/183 (45%), Gaps = 10/183 (5%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS---STLR 274
            L V G+SF++  GE + ++       + L   L  +++   G I I+G P+A     TLR
Sbjct: 1280 LAVQGVSFKIHAGEKVGIVGRTGAGKSSLASGLLRLQEAAEGGIWIDGVPIAHVGLHTLR 1339

Query: 275  KVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEEL-GLEQVR 333
              ++ +  D  L P      +LR +  L +  +  +     +  ++  L+  L G  Q +
Sbjct: 1340 SRISIIPQDPILFP-----GSLRMNLDLLQEHSDEAIWAALETVQLKALVASLPGQLQYK 1394

Query: 334  DTNVGR-LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
              + G  L+  + + L +A  LL    ILILD+ T  +D      +   L +W +   V+
Sbjct: 1395 CADRGEDLSVGQKQLLCLARALLRKTQILILDEATAAVDPGTELQMQAMLGSWFAQCTVL 1454

Query: 393  IMS 395
            +++
Sbjct: 1455 LIA 1457


>AF076622-1|AAC79696.1| 1503|Homo sapiens MRP6 protein.
          Length = 1503

 Score = 41.1 bits (92), Expect = 0.016
 Identities = 44/183 (24%), Positives = 83/183 (45%), Gaps = 10/183 (5%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS---STLR 274
            L V G+SF++  GE + ++       + L   L  +++   G I I+G P+A     TLR
Sbjct: 1280 LAVQGVSFKIHAGEKVGIVGRTGAGKSSLASGLLRLQEAAEGGIWIDGVPIAHVGLHTLR 1339

Query: 275  KVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEEL-GLEQVR 333
              ++ +  D  L P      +LR +  L +  +  +     +  ++  L+  L G  Q +
Sbjct: 1340 SRISIIPQDPILFP-----GSLRMNLDLLQEHSDEAIWAALETVQLKALVASLPGQLQYK 1394

Query: 334  DTNVGR-LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
              + G  L+  + + L +A  LL    ILILD+ T  +D      +   L +W +   V+
Sbjct: 1395 CADRGEDLSVGQKQLLCLARALLRKTQILILDEATAAVDPGTELQMQAMLGSWFAQCTVL 1454

Query: 393  IMS 395
            +++
Sbjct: 1455 LIA 1457


>M23234-1|AAA36207.1| 1279|Homo sapiens protein ( Human membrane
            glycoprotein P (mdr3) mRNA, complete cds. ).
          Length = 1279

 Score = 40.7 bits (91), Expect = 0.021
 Identities = 55/245 (22%), Positives = 101/245 (41%), Gaps = 18/245 (7%)

Query: 201  NYYVNSLEITSPENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGD 260
            N   N +    P   +  V+ GLS EVK G+ LA++ ++    + ++ +L      L+G 
Sbjct: 1033 NITFNEVVFNYPTRANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGT 1092

Query: 261  IVINGQPVAS---STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDR 317
            ++++GQ         LR  +  V  +  L      E+    +    +  +    V     
Sbjct: 1093 VLLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIAENIA--YGDNSRVVSQDEIVSAAKA 1150

Query: 318  DRINLLIEELGLEQVRDTNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIF 373
              I+  IE   L    +T VG    +L+  + +R+ +A  L+    IL+LD+ T  +D  
Sbjct: 1151 ANIHPFIET--LPHKYETRVGDKGTQLSGGQKQRIAIARALIRQPQILLLDEATSALDT- 1207

Query: 374  DTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLP---- 429
            ++  +V+   + A  GR  I+  H            +V+   GR    G  + +L     
Sbjct: 1208 ESEKVVQEALDKAREGRTCIVIAH--RLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGI 1265

Query: 430  YFSSI 434
            YFS +
Sbjct: 1266 YFSMV 1270


>AF168791-1|AAD51293.1| 1503|Homo sapiens multi-specific organic anion
            tranporter-E protein.
          Length = 1503

 Score = 39.9 bits (89), Expect = 0.036
 Identities = 43/173 (24%), Positives = 77/173 (44%), Gaps = 10/173 (5%)

Query: 218  LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS---STLR 274
            L V G+SF++  GE + ++       + L   L  +++   G I I+G P+A     TLR
Sbjct: 1280 LAVQGVSFKIHAGEKVGIVGRTGAGKSSLASGLLRLQEAAEGGIWIDGVPIAHVGLHTLR 1339

Query: 275  KVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEEL-GLEQVR 333
              ++ +  D  L P      +LR +  L +  +  +     +  ++  L+  L G  Q +
Sbjct: 1340 SRISIIPQDPILFP-----GSLRMNLDLLQEHSDEAIWAALETVQLKALVASLPGQLQYK 1394

Query: 334  DTNVGR-LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNW 385
              + G  L+  + + L +A  LL    ILILD+ T  +D      +   L +W
Sbjct: 1395 CADRGEDLSVGQKQLLCLARALLRKTQILILDEATAAVDPGTELQMQAMLGSW 1447


>X95715-1|CAA65019.1|  453|Homo sapiens anthracycline resistance
           associated protein protein.
          Length = 453

 Score = 39.5 bits (88), Expect = 0.047
 Identities = 44/183 (24%), Positives = 83/183 (45%), Gaps = 10/183 (5%)

Query: 218 LVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS---STLR 274
           L V G+SF++  GE + ++       + L   L  +++   G I I+G P+A     TLR
Sbjct: 230 LAVQGVSFKIHAGEKVGIVGRTGAGKSSLASGLLRLQEAAEGGIWIDGVPIAHVGVHTLR 289

Query: 275 KVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEEL-GLEQVR 333
             ++ +  D  L P      +LR +  L +  +  +     +  ++  L+  L G  Q +
Sbjct: 290 SRISIIPQDPILFP-----GSLRMNLDLLQEHSDEAIWAALETVQLKALVACLPGQLQYK 344

Query: 334 DTNVGR-LTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
             + G  L+  + + L +A  LL    ILILD+ T  +D      +   L +W +   V+
Sbjct: 345 CADRGEDLSVGQKQLLCLARALLRKTQILILDEATAAVDPGTELQMQAMLGSWFAQCTVL 404

Query: 393 IMS 395
           +++
Sbjct: 405 LIA 407


>U18236-1|AAA84437.2|  131|Homo sapiens ATP-binding cassette protein
           protein.
          Length = 131

 Score = 39.5 bits (88), Expect = 0.047
 Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 1/90 (1%)

Query: 324 IEELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLR 383
           +E+L L +  D   G  +    R+L+ A  L+   A + LD+PT  MD     FL   + 
Sbjct: 6   LEKLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLIL 65

Query: 384 NWASTGRVVIMSLHPPTYEIFAMLTKVVLI 413
           +   TGR V+++ H    E  A+ T++ ++
Sbjct: 66  DLIKTGRSVVLTSH-SMEECEALCTRLAIM 94


>M29447-1|AAA59576.1| 1280|Homo sapiens P glycoprotein protein.
          Length = 1280

 Score = 38.7 bits (86), Expect = 0.083
 Identities = 50/233 (21%), Positives = 101/233 (43%), Gaps = 16/233 (6%)

Query: 212  PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASS 271
            P      V+ GLS EVK G+ LA++ ++    + ++ +L      L+G ++++G+ +   
Sbjct: 1045 PTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRL 1104

Query: 272  TLRKVVAY--VRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGL 329
             ++ + A+  + +   +    S+   + +    R   +    V+      I+  IE   L
Sbjct: 1105 NVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVV-SQEEIVRAAKEANIHAFIE--SL 1161

Query: 330  EQVRDTNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNW 385
                 T VG    +L+  + +R+ +A  L+    IL+LD+ T  +D  ++  +V+   + 
Sbjct: 1162 PNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDT-ESEKVVQEALDK 1220

Query: 386  ASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLP----YFSSI 434
            A  GR  I+  H            +V+   GR    G  + +L     YFS +
Sbjct: 1221 AREGRTCIVIAH--RLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMV 1271


>M14758-1|AAA59575.1| 1280|Homo sapiens PGY1 protein.
          Length = 1280

 Score = 38.7 bits (86), Expect = 0.083
 Identities = 50/233 (21%), Positives = 101/233 (43%), Gaps = 16/233 (6%)

Query: 212  PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASS 271
            P      V+ GLS EVK G+ LA++ ++    + ++ +L      L+G ++++G+ +   
Sbjct: 1045 PTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRL 1104

Query: 272  TLRKVVAY--VRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGL 329
             ++ + A+  + +   +    S+   + +    R   +    V+      I+  IE   L
Sbjct: 1105 NVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVV-SQEEIVRAAKEANIHAFIE--SL 1161

Query: 330  EQVRDTNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNW 385
                 T VG    +L+  + +R+ +A  L+    IL+LD+ T  +D  ++  +V+   + 
Sbjct: 1162 PNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDT-ESEKVVQEALDK 1220

Query: 386  ASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLP----YFSSI 434
            A  GR  I+  H            +V+   GR    G  + +L     YFS +
Sbjct: 1221 AREGRTCIVIAH--RLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMV 1271


>BC130424-1|AAI30425.1| 1280|Homo sapiens ATP-binding cassette,
            sub-family B (MDR/TAP), member 1 protein.
          Length = 1280

 Score = 38.7 bits (86), Expect = 0.083
 Identities = 50/233 (21%), Positives = 101/233 (43%), Gaps = 16/233 (6%)

Query: 212  PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASS 271
            P      V+ GLS EVK G+ LA++ ++    + ++ +L      L+G ++++G+ +   
Sbjct: 1045 PTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRL 1104

Query: 272  TLRKVVAY--VRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGL 329
             ++ + A+  + +   +    S+   + +    R   +    V+      I+  IE   L
Sbjct: 1105 NVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVV-SQEEIVRAAKEANIHAFIE--SL 1161

Query: 330  EQVRDTNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNW 385
                 T VG    +L+  + +R+ +A  L+    IL+LD+ T  +D  ++  +V+   + 
Sbjct: 1162 PNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDT-ESEKVVQEALDK 1220

Query: 386  ASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLP----YFSSI 434
            A  GR  I+  H            +V+   GR    G  + +L     YFS +
Sbjct: 1221 AREGRTCIVIAH--RLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMV 1271


>BC051884-1|AAH51884.2|  709|Homo sapiens ATP-binding cassette,
           sub-family F (GCN20), member 3 protein.
          Length = 709

 Score = 38.7 bits (86), Expect = 0.083
 Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 6/87 (6%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAM 406
           RL +A  L     +L+LD+PT  +D+    +L  YL+ W ST  ++++S H   + + A+
Sbjct: 335 RLALARALFARPDLLLLDEPTNMLDVRAILWLENYLQTWPST--ILVVS-HDRNF-LNAI 390

Query: 407 LTKVVLISAGRTMFSGYRRDMLPYFSS 433
            T ++ + + R    GYR D   +  S
Sbjct: 391 ATDIIHLHSQR--LDGYRGDFETFIKS 415


>BC051754-1|AAH51754.1|  709|Homo sapiens ATP-binding cassette,
           sub-family F (GCN20), member 3 protein.
          Length = 709

 Score = 38.7 bits (86), Expect = 0.083
 Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 6/87 (6%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAM 406
           RL +A  L     +L+LD+PT  +D+    +L  YL+ W ST  ++++S H   + + A+
Sbjct: 335 RLALARALFARPDLLLLDEPTNMLDVRAILWLENYLQTWPST--ILVVS-HDRNF-LNAI 390

Query: 407 LTKVVLISAGRTMFSGYRRDMLPYFSS 433
            T ++ + + R    GYR D   +  S
Sbjct: 391 ATDIIHLHSQR--LDGYRGDFETFIKS 415


>BC009253-1|AAH09253.1|  709|Homo sapiens ATP-binding cassette,
           sub-family F (GCN20), member 3 protein.
          Length = 709

 Score = 38.7 bits (86), Expect = 0.083
 Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 6/87 (6%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAM 406
           RL +A  L     +L+LD+PT  +D+    +L  YL+ W ST  ++++S H   + + A+
Sbjct: 335 RLALARALFARPDLLLLDEPTNMLDVRAILWLENYLQTWPST--ILVVS-HDRNF-LNAI 390

Query: 407 LTKVVLISAGRTMFSGYRRDMLPYFSS 433
            T ++ + + R    GYR D   +  S
Sbjct: 391 ATDIIHLHSQR--LDGYRGDFETFIKS 415


>AY910577-1|AAW82430.1| 1280|Homo sapiens ATP-binding cassette,
            sub-family B (MDR/TAP), member 1 protein.
          Length = 1280

 Score = 38.7 bits (86), Expect = 0.083
 Identities = 50/233 (21%), Positives = 101/233 (43%), Gaps = 16/233 (6%)

Query: 212  PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASS 271
            P      V+ GLS EVK G+ LA++ ++    + ++ +L      L+G ++++G+ +   
Sbjct: 1045 PTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRL 1104

Query: 272  TLRKVVAY--VRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGL 329
             ++ + A+  + +   +    S+   + +    R   +    V+      I+  IE   L
Sbjct: 1105 NVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVV-SQEEIVRAAKEANIHAFIE--SL 1161

Query: 330  EQVRDTNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNW 385
                 T VG    +L+  + +R+ +A  L+    IL+LD+ T  +D  ++  +V+   + 
Sbjct: 1162 PNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDT-ESEKVVQEALDK 1220

Query: 386  ASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLP----YFSSI 434
            A  GR  I+  H            +V+   GR    G  + +L     YFS +
Sbjct: 1221 AREGRTCIVIAH--RLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMV 1271


>AK092415-1|BAC03881.1|  703|Homo sapiens protein ( Homo sapiens
           cDNA FLJ35096 fis, clone PLACE6006217, weakly similar to
           GCN20 PROTEIN. ).
          Length = 703

 Score = 38.7 bits (86), Expect = 0.083
 Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 6/87 (6%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAM 406
           RL +A  L     +L+LD+PT  +D+    +L  YL+ W ST  ++++S H   + + A+
Sbjct: 329 RLALARALFARPDLLLLDEPTNMLDVRAILWLENYLQTWPST--ILVVS-HDRNF-LNAI 384

Query: 407 LTKVVLISAGRTMFSGYRRDMLPYFSS 433
            T ++ + + R    GYR D   +  S
Sbjct: 385 ATDIIHLHSQR--LDGYRGDFETFIKS 409


>AK024758-1|BAB14989.1|  390|Homo sapiens protein ( Homo sapiens
           cDNA: FLJ21105 fis, clone CAS05114. ).
          Length = 390

 Score = 38.7 bits (86), Expect = 0.083
 Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 6/87 (6%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAM 406
           RL +A  L     +L+LD+PT  +D+    +L  YL+ W ST  ++++S H   + + A+
Sbjct: 16  RLALARALFARPDLLLLDEPTNMLDVRAILWLENYLQTWPST--ILVVS-HDRNF-LNAI 71

Query: 407 LTKVVLISAGRTMFSGYRRDMLPYFSS 433
            T ++ + + R    GYR D   +  S
Sbjct: 72  ATDIIHLHSQR--LDGYRGDFETFIKS 96


>AK002060-1|BAA92063.1|  709|Homo sapiens protein ( Homo sapiens
           cDNA FLJ11198 fis, clone PLACE1007697, weakly similar to
           GCN20 PROTEIN. ).
          Length = 709

 Score = 38.7 bits (86), Expect = 0.083
 Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 6/87 (6%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLHPPTYEIFAM 406
           RL +A  L     +L+LD+PT  +D+    +L  YL+ W ST  ++++S H   + + A+
Sbjct: 335 RLALARALFARPDLLLLDEPTNMLDVRAILWLENYLQTWPST--ILVVS-HDRNF-LNAI 390

Query: 407 LTKVVLISAGRTMFSGYRRDMLPYFSS 433
            T ++ + + R    GYR D   +  S
Sbjct: 391 ATDIIHLHSQR--LDGYRGDFETFIKS 415


>AF016535-1|AAB69423.1| 1279|Homo sapiens P-glycoprotein protein.
          Length = 1279

 Score = 38.7 bits (86), Expect = 0.083
 Identities = 50/233 (21%), Positives = 101/233 (43%), Gaps = 16/233 (6%)

Query: 212  PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASS 271
            P      V+ GLS EVK G+ LA++ ++    + ++ +L      L+G ++++G+ +   
Sbjct: 1044 PTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRL 1103

Query: 272  TLRKVVAY--VRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGL 329
             ++ + A+  + +   +    S+   + +    R   +    V+      I+  IE   L
Sbjct: 1104 NVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVV-SQEEIVRAAKEANIHAFIE--SL 1160

Query: 330  EQVRDTNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNW 385
                 T VG    +L+  + +R+ +A  L+    IL+LD+ T  +D  ++  +V+   + 
Sbjct: 1161 PNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDT-ESEKVVQEALDK 1219

Query: 386  ASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLP----YFSSI 434
            A  GR  I+  H            +V+   GR    G  + +L     YFS +
Sbjct: 1220 AREGRTCIVIAH--RLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMV 1270


>AB208970-1|BAD92207.1| 1062|Homo sapiens Multidrug resistance protein
            1 variant protein.
          Length = 1062

 Score = 38.7 bits (86), Expect = 0.083
 Identities = 50/233 (21%), Positives = 101/233 (43%), Gaps = 16/233 (6%)

Query: 212  PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASS 271
            P      V+ GLS EVK G+ LA++ ++    + ++ +L      L+G ++++G+ +   
Sbjct: 827  PTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRL 886

Query: 272  TLRKVVAY--VRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGL 329
             ++ + A+  + +   +    S+   + +    R   +    V+      I+  IE   L
Sbjct: 887  NVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVV-SQEEIVRAAKEANIHAFIE--SL 943

Query: 330  EQVRDTNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNW 385
                 T VG    +L+  + +R+ +A  L+    IL+LD+ T  +D  ++  +V+   + 
Sbjct: 944  PNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDT-ESEKVVQEALDK 1002

Query: 386  ASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDMLP----YFSSI 434
            A  GR  I+  H            +V+   GR    G  + +L     YFS +
Sbjct: 1003 AREGRTCIVIAH--RLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMV 1053


>AL137481-1|CAB70762.1|  269|Homo sapiens hypothetical protein
           protein.
          Length = 269

 Score = 38.3 bits (85), Expect = 0.11
 Identities = 44/180 (24%), Positives = 64/180 (35%), Gaps = 8/180 (4%)

Query: 220 VSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS--STLRKVV 277
           V  L   +  GE   +L       T    ++ G      G+ V+ G  VA   S     +
Sbjct: 91  VDRLCLGIPPGECFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSM 150

Query: 278 AYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNV 337
            Y     A+   ++    L   A LR           G        +  LGL    D   
Sbjct: 151 GYCPQSDAIFELLTGREHLELLARLRGVPEAQVAQTAGSG------LARLGLSWYADRPA 204

Query: 338 GRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
           G  +    R+L  A  L+ D A++ LD+PT  MD     FL   L      GR V+++ H
Sbjct: 205 GTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLAVVREGRSVMLTSH 264


>L21207-1|AAC12905.1|  748|Homo sapiens peptide transporter protein.
          Length = 748

 Score = 37.1 bits (82), Expect = 0.25
 Identities = 41/170 (24%), Positives = 78/170 (45%), Gaps = 18/170 (10%)

Query: 212 PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS- 270
           P     LV+ GL+F ++ GE+ A++       + +  +L  + +   G ++++G+P+   
Sbjct: 513 PNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQY 572

Query: 271 --STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKP---RNTHSHVKMGDRDRINLLIE 325
               L + VA V  +  +    S++  + +    +KP     T + VK G    I+    
Sbjct: 573 EHRYLHRQVAAVGQEPQVF-GRSLQENIAY-GLTQKPTMEEITAAAVKSGAHSFIS---- 626

Query: 326 ELGLEQVRDTNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
             GL Q  DT VG    +L+  + + + +A  L+    +LILD  T  +D
Sbjct: 627 --GLPQGYDTEVGEAGSQLSGGQQQAVALARALIRKPCVLILDDATSALD 674


>L21206-1|AAC12904.1|  748|Homo sapiens peptide transporter protein.
          Length = 748

 Score = 37.1 bits (82), Expect = 0.25
 Identities = 41/170 (24%), Positives = 78/170 (45%), Gaps = 18/170 (10%)

Query: 212 PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS- 270
           P     LV+ GL+F ++ GE+ A++       + +  +L  + +   G ++++G+P+   
Sbjct: 513 PNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQY 572

Query: 271 --STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKP---RNTHSHVKMGDRDRINLLIE 325
               L + VA V  +  +    S++  + +    +KP     T + VK G    I+    
Sbjct: 573 EHRYLHRQVAAVGQEPQVF-GRSLQENIAY-GLTQKPTMEEITAAAVKSGAHSFIS---- 626

Query: 326 ELGLEQVRDTNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
             GL Q  DT VG    +L+  + + + +A  L+    +LILD  T  +D
Sbjct: 627 --GLPQGYDTEVGEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALD 674


>L21205-1|AAC12903.1|  748|Homo sapiens peptide transporter protein.
          Length = 748

 Score = 37.1 bits (82), Expect = 0.25
 Identities = 41/170 (24%), Positives = 78/170 (45%), Gaps = 18/170 (10%)

Query: 212 PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS- 270
           P     LV+ GL+F ++ GE+ A++       + +  +L  + +   G ++++G+P+   
Sbjct: 513 PNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQY 572

Query: 271 --STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKP---RNTHSHVKMGDRDRINLLIE 325
               L + VA V  +  +    S++  + +    +KP     T + VK G    I+    
Sbjct: 573 EHRYLHRQVAAVGQEPQVF-GRSLQENIAY-GLTQKPTMEEITAAAVKSGAHSFIS---- 626

Query: 326 ELGLEQVRDTNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
             GL Q  DT VG    +L+  + + + +A  L+    +LILD  T  +D
Sbjct: 627 --GLPQGYDTEVGEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALD 674


>BC141836-1|AAI41837.1|  693|Homo sapiens Unknown (protein for
           MGC:165100) protein.
          Length = 693

 Score = 37.1 bits (82), Expect = 0.25
 Identities = 44/207 (21%), Positives = 92/207 (44%), Gaps = 10/207 (4%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS---STLR- 274
           V+   +  +  G+I+A++  +    T +  +L       +G ++++G+ + +   S LR 
Sbjct: 472 VLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRG 531

Query: 275 KVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRD 334
           +VV ++  +  L  T  +E+ +RF          ++  +  +         E G   V  
Sbjct: 532 QVVGFISQEPVLFGTTIMEN-IRFGKLEASDEEVYTAAREANAHEFITSFPE-GYNTVVG 589

Query: 335 TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
                L+  + +RL +A  L+    +LILD+ T  +D  ++  +V+   + AS GR V+ 
Sbjct: 590 ERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDA-ESERVVQEALDRASAGRTVLA 648

Query: 395 SLHPPTYE---IFAMLTKVVLISAGRT 418
             H    +   ++A L +   + A RT
Sbjct: 649 GTHEELLKKGGLYAELIRRQALDAPRT 675


>BC141814-1|AAI41815.1|  718|Homo sapiens ATP-binding cassette,
           sub-family B (MDR/TAP), member 8 protein.
          Length = 718

 Score = 37.1 bits (82), Expect = 0.25
 Identities = 45/214 (21%), Positives = 97/214 (45%), Gaps = 9/214 (4%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS---STLR- 274
           V+   +  +  G+I+A++  +    T +  +L       +G ++++G+ + +   S LR 
Sbjct: 472 VLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRG 531

Query: 275 KVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRD 334
           +VV ++  +  L  T  +E+ +RF          ++  +  +         E G   V  
Sbjct: 532 QVVGFISQEPVLFGTTIMEN-IRFGKLEASDEEVYTAAREANAHEFITSFPE-GYNTVVG 589

Query: 335 TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
                L+  + +RL +A  L+    +LILD+ T  +D  ++  +V+   + AS GR V++
Sbjct: 590 ERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDA-ESERVVQEALDRASAGRTVLV 648

Query: 395 SLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDML 428
             H  +    A    +V+++ GR   +G   ++L
Sbjct: 649 IAHRLSTVRGAHC--IVVMADGRVWEAGTHEELL 680


>AY523971-1|AAS55412.1|  748|Homo sapiens TAP1 protein.
          Length = 748

 Score = 37.1 bits (82), Expect = 0.25
 Identities = 41/170 (24%), Positives = 78/170 (45%), Gaps = 18/170 (10%)

Query: 212 PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS- 270
           P     LV+ GL+F ++ GE+ A++       + +  +L  + +   G ++++G+P+   
Sbjct: 513 PNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQY 572

Query: 271 --STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKP---RNTHSHVKMGDRDRINLLIE 325
               L + VA V  +  +    S++  + +    +KP     T + VK G    I+    
Sbjct: 573 EHRYLHRQVAAVGQEPQVF-GRSLQENIAY-GLTQKPTMEEITAAAVKSGAHSFIS---- 626

Query: 326 ELGLEQVRDTNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
             GL Q  DT VG    +L+  + + + +A  L+    +LILD  T  +D
Sbjct: 627 --GLPQGYDTEVGEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALD 674


>AK222911-1|BAD96631.1|  718|Homo sapiens ATP-binding cassette,
           sub-family B, member 8 variant protein.
          Length = 718

 Score = 37.1 bits (82), Expect = 0.25
 Identities = 45/214 (21%), Positives = 97/214 (45%), Gaps = 9/214 (4%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS---STLR- 274
           V+   +  +  G+I+A++  +    T +  +L       +G ++++G+ + +   S LR 
Sbjct: 472 VLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRG 531

Query: 275 KVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRD 334
           +VV ++  +  L  T  +E+ +RF          ++  +  +         E G   V  
Sbjct: 532 QVVGFISQEPVLFGTTIMEN-IRFGKLEASDEEVYTAAREANAHEFITSFPE-GYNTVVG 589

Query: 335 TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
                L+  + +RL +A  L+    +LILD+ T  +D  ++  +V+   + AS GR V++
Sbjct: 590 ERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDA-ESERVVQEALDRASAGRTVLV 648

Query: 395 SLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDML 428
             H  +    A    +V+++ GR   +G   ++L
Sbjct: 649 IAHRLSTVRGAHC--IVVMADGRVWEAGTHEELL 680


>AK094636-1|BAC04392.1|  701|Homo sapiens protein ( Homo sapiens
           cDNA FLJ37317 fis, clone BRAMY2017455, highly similar to
           Homo sapiens ATP-binding cassette protein M-ABC1 mRNA.
           ).
          Length = 701

 Score = 37.1 bits (82), Expect = 0.25
 Identities = 45/214 (21%), Positives = 97/214 (45%), Gaps = 9/214 (4%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS---STLR- 274
           V+   +  +  G+I+A++  +    T +  +L       +G ++++G+ + +   S LR 
Sbjct: 455 VLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRG 514

Query: 275 KVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRD 334
           +VV ++  +  L  T  +E+ +RF          ++  +  +         E G   V  
Sbjct: 515 QVVGFISQEPVLFGTTIMEN-IRFGKLEASDEEVYTAAREANAHEFITSFPE-GYNTVVG 572

Query: 335 TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
                L+  + +RL +A  L+    +LILD+ T  +D  ++  +V+   + AS GR V++
Sbjct: 573 ERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDA-ESERVVQEALDRASAGRTVLV 631

Query: 395 SLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDML 428
             H  +    A    +V+++ GR   +G   ++L
Sbjct: 632 IAHRLSTVRGAHC--IVVMADGRVWEAGTHEELL 663


>AK002018-1|BAA92038.1|  735|Homo sapiens protein ( Homo sapiens
           cDNA FLJ11156 fis, clone PLACE1006956, weakly similar to
           ATP-DEPENDENT PERMEASE MDL1. ).
          Length = 735

 Score = 37.1 bits (82), Expect = 0.25
 Identities = 45/214 (21%), Positives = 97/214 (45%), Gaps = 9/214 (4%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS---STLR- 274
           V+   +  +  G+I+A++  +    T +  +L       +G ++++G+ + +   S LR 
Sbjct: 489 VLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRG 548

Query: 275 KVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRD 334
           +VV ++  +  L  T  +E+ +RF          ++  +  +         E G   V  
Sbjct: 549 QVVGFISQEPVLFGTTIMEN-IRFGKLEASDEEVYTAAREANAHEFITSFPE-GYNTVVG 606

Query: 335 TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
                L+  + +RL +A  L+    +LILD+ T  +D  ++  +V+   + AS GR V++
Sbjct: 607 ERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDA-ESERVVQEALDRASAGRTVLV 665

Query: 395 SLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDML 428
             H  +    A    +V+++ GR   +G   ++L
Sbjct: 666 IAHRLSTVRGAHC--IVVMADGRVWEAGTHEELL 697


>AF047690-1|AAD15748.1|  718|Homo sapiens ATP-binding cassette
           protein M-ABC1 protein.
          Length = 718

 Score = 37.1 bits (82), Expect = 0.25
 Identities = 45/214 (21%), Positives = 97/214 (45%), Gaps = 9/214 (4%)

Query: 219 VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS---STLR- 274
           V+   +  +  G+I+A++  +    T +  +L       +G ++++G+ + +   S LR 
Sbjct: 472 VLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRG 531

Query: 275 KVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRD 334
           +VV ++  +  L  T  +E+ +RF          ++  +  +         E G   V  
Sbjct: 532 QVVGFISQEPVLFGTTIMEN-IRFGKLEASDEEVYTAAREANAHEFITSFPE-GYNTVVG 589

Query: 335 TNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIM 394
                L+  + +RL +A  L+    +LILD+ T  +D  ++  +V+   + AS GR V++
Sbjct: 590 ERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDA-ESERVVQEALDRASAGRTVLV 648

Query: 395 SLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDML 428
             H  +    A    +V+++ GR   +G   ++L
Sbjct: 649 IAHRLSTVRGAHC--IVVMADGRVWEAGTHEELL 680


>AY523970-1|AAS55411.1|  748|Homo sapiens TAP1 protein.
          Length = 748

 Score = 36.7 bits (81), Expect = 0.33
 Identities = 41/170 (24%), Positives = 78/170 (45%), Gaps = 18/170 (10%)

Query: 212 PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS- 270
           P     LV+ GL+F ++ GE+ A++       + +  +L  + +   G ++++G+P+   
Sbjct: 513 PNRPDILVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQY 572

Query: 271 --STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKP---RNTHSHVKMGDRDRINLLIE 325
               L + VA V  +  +    S++  + +    +KP     T + VK G    I+    
Sbjct: 573 EHRYLHRQVAAVGQEPQVF-GRSLQENIAY-GLTQKPTMEEITAAAVKSGAHSFIS---- 626

Query: 326 ELGLEQVRDTNVG----RLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
             GL Q  DT VG    +L+  + + + +A  L+    +LILD  T  +D
Sbjct: 627 --GLPQGYDTEVGEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALD 674


>AK128516-1|BAC87475.1|  788|Homo sapiens protein ( Homo sapiens
           cDNA FLJ46673 fis, clone TRACH3009061, weakly  similar
           to ATP-binding cassette, sub-family A, member 1. ).
          Length = 788

 Score = 36.7 bits (81), Expect = 0.33
 Identities = 49/209 (23%), Positives = 85/209 (40%), Gaps = 15/209 (7%)

Query: 215 KSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVIN---GQPV--- 268
           ++ + V  +S  +  GE   +L       +    +L G     SG  +I    G  V   
Sbjct: 462 QNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLS 521

Query: 269 ASSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRK-PRNTHSHVKMGDRDRINLLIEEL 327
           ++ T   ++ Y     AL   ++    L ++ +LR  PR     V  GD      LI  L
Sbjct: 522 SAGTAGVLIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVA-GD------LIRRL 574

Query: 328 GLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWAS 387
            LE   D  V   +    R+L+ A  L+    IL+LD+P+  MD     +L + +     
Sbjct: 575 HLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVR 634

Query: 388 TGRVVIMSLHPPTYEIFAMLTKVVLISAG 416
            G   +++ H    E  A+ T++ ++  G
Sbjct: 635 EGCAAVLTSH-SMEECEALCTRLAIMVNG 662


>BX248518-7|CAM26017.1|  845|Homo sapiens ATP-binding cassette
           sub-family F (GCN20) member 1 protein.
          Length = 845

 Score = 36.3 bits (80), Expect = 0.44
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
           R+++A  L ++  +L+LD+PT  +D+    +L  YL+ W  T  +V
Sbjct: 459 RVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIV 504


>BX248518-6|CAM26016.1|  807|Homo sapiens ATP-binding cassette
           sub-family F (GCN20) member 1 protein.
          Length = 807

 Score = 36.3 bits (80), Expect = 0.44
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
           R+++A  L ++  +L+LD+PT  +D+    +L  YL+ W  T  +V
Sbjct: 421 RVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIV 466


>BX119957-3|CAM25907.1|  845|Homo sapiens ATP-binding cassette
           sub-family F (GCN20) member 1 protein.
          Length = 845

 Score = 36.3 bits (80), Expect = 0.44
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
           R+++A  L ++  +L+LD+PT  +D+    +L  YL+ W  T  +V
Sbjct: 459 RVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIV 504


>BX119957-2|CAM25906.1|  807|Homo sapiens ATP-binding cassette
           sub-family F (GCN20) member 1 protein.
          Length = 807

 Score = 36.3 bits (80), Expect = 0.44
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
           R+++A  L ++  +L+LD+PT  +D+    +L  YL+ W  T  +V
Sbjct: 421 RVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIV 466


>BX000357-8|CAI18563.1|  845|Homo sapiens ATP-binding cassette,
           sub-family F (GCN20), member 1 protein.
          Length = 845

 Score = 36.3 bits (80), Expect = 0.44
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
           R+++A  L ++  +L+LD+PT  +D+    +L  YL+ W  T  +V
Sbjct: 459 RVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIV 504


>BX000357-6|CAI18562.1|  807|Homo sapiens ATP-binding cassette,
           sub-family F (GCN20), member 1 protein.
          Length = 807

 Score = 36.3 bits (80), Expect = 0.44
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
           R+++A  L ++  +L+LD+PT  +D+    +L  YL+ W  T  +V
Sbjct: 421 RVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIV 466


>BC112923-1|AAI12924.1|  845|Homo sapiens ATP-binding cassette,
           sub-family F (GCN20), member 1 protein.
          Length = 845

 Score = 36.3 bits (80), Expect = 0.44
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
           R+++A  L ++  +L+LD+PT  +D+    +L  YL+ W  T  +V
Sbjct: 459 RVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIV 504


>BC034488-1|AAH34488.1|  845|Homo sapiens ATP-binding cassette,
           sub-family F (GCN20), member 1 protein.
          Length = 845

 Score = 36.3 bits (80), Expect = 0.44
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
           R+++A  L ++  +L+LD+PT  +D+    +L  YL+ W  T  +V
Sbjct: 459 RVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIV 504


>BA000025-75|BAB63325.1|  807|Homo sapiens TNFalpha-inducible
           ATP-binding protein protein.
          Length = 807

 Score = 36.3 bits (80), Expect = 0.44
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
           R+++A  L ++  +L+LD+PT  +D+    +L  YL+ W  T  +V
Sbjct: 421 RVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIV 466


>AL662825-8|CAI17836.1|  807|Homo sapiens ATP-binding cassette,
           sub-family F (GCN20), member 1 protein.
          Length = 807

 Score = 36.3 bits (80), Expect = 0.44
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
           R+++A  L ++  +L+LD+PT  +D+    +L  YL+ W  T  +V
Sbjct: 421 RVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIV 466


>AL662825-7|CAI17837.1|  845|Homo sapiens ATP-binding cassette,
           sub-family F (GCN20), member 1 protein.
          Length = 845

 Score = 36.3 bits (80), Expect = 0.44
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
           R+++A  L ++  +L+LD+PT  +D+    +L  YL+ W  T  +V
Sbjct: 459 RVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIV 504


>AL662800-8|CAI18158.1|  845|Homo sapiens ATP-binding cassette,
           sub-family F (GCN20), member 1 protein.
          Length = 845

 Score = 36.3 bits (80), Expect = 0.44
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
           R+++A  L ++  +L+LD+PT  +D+    +L  YL+ W  T  +V
Sbjct: 459 RVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIV 504


>AL662800-7|CAI18159.1|  807|Homo sapiens ATP-binding cassette,
           sub-family F (GCN20), member 1 protein.
          Length = 807

 Score = 36.3 bits (80), Expect = 0.44
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
           R+++A  L ++  +L+LD+PT  +D+    +L  YL+ W  T  +V
Sbjct: 421 RVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIV 466


>AF027302-1|AAC70891.1|  807|Homo sapiens TNF-alpha stimulated ABC
           protein protein.
          Length = 807

 Score = 36.3 bits (80), Expect = 0.44
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
           R+++A  L ++  +L+LD+PT  +D+    +L  YL+ W  T  +V
Sbjct: 421 RVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIV 466


>AB209564-1|BAD92801.1|  593|Homo sapiens ATP-binding cassette,
           sub-family F, member 1 variant protein.
          Length = 593

 Score = 36.3 bits (80), Expect = 0.44
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
           R+++A  L ++  +L+LD+PT  +D+    +L  YL+ W  T  +V
Sbjct: 207 RVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIV 252


>AB202093-1|BAE78612.1|  807|Homo sapiens ATP-binding cassette,
           sub-family F (GCN20), member 1 protein.
          Length = 807

 Score = 36.3 bits (80), Expect = 0.44
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
           R+++A  L ++  +L+LD+PT  +D+    +L  YL+ W  T  +V
Sbjct: 421 RVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIV 466


>AB103602-1|BAF31263.1|  807|Homo sapiens ABC50 protein protein.
          Length = 807

 Score = 36.3 bits (80), Expect = 0.44
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
           R+++A  L ++  +L+LD+PT  +D+    +L  YL+ W  T  +V
Sbjct: 421 RVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIV 466


>AB088096-1|BAC54928.1|  807|Homo sapiens ATP-binding cassette,
           sub-family F (GCN20), member 1 protein.
          Length = 807

 Score = 36.3 bits (80), Expect = 0.44
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 347 RLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVV 392
           R+++A  L ++  +L+LD+PT  +D+    +L  YL+ W  T  +V
Sbjct: 421 RVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIV 466


>X87344-5|CAA60785.1|  748|Homo sapiens TAP1 protein.
          Length = 748

 Score = 35.1 bits (77), Expect = 1.0
 Identities = 37/166 (22%), Positives = 76/166 (45%), Gaps = 10/166 (6%)

Query: 212 PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS- 270
           P     LV+ GL+F ++ GE+ A++       + +  +L  + +   G ++++G+P+   
Sbjct: 513 PNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQY 572

Query: 271 --STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKP---RNTHSHVKMGDRDRINLLIE 325
               L + VA V  +  +    S++  + +    +KP     T + VK G    I+ L +
Sbjct: 573 EHRYLHRQVAAVGQEPQVF-GRSLQENIAY-GLTQKPTMEEITAAAVKSGAHSFISGLPQ 630

Query: 326 ELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
             G +   D    +L+  + + + +A  L+    +LILD  T  +D
Sbjct: 631 --GYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALD 674


>X66401-2|CAA47025.1|  748|Homo sapiens ABC-transporter protein.
          Length = 748

 Score = 35.1 bits (77), Expect = 1.0
 Identities = 37/166 (22%), Positives = 76/166 (45%), Gaps = 10/166 (6%)

Query: 212 PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS- 270
           P     LV+ GL+F ++ GE+ A++       + +  +L  + +   G ++++G+P+   
Sbjct: 513 PNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQY 572

Query: 271 --STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKP---RNTHSHVKMGDRDRINLLIE 325
               L + VA V  +  +    S++  + +    +KP     T + VK G    I+ L +
Sbjct: 573 EHRYLHRQVAAVGQEPQVF-GRSLQENIAY-GLTQKPTMEEITAAAVKSGAHSFISGLPQ 630

Query: 326 ELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
             G +   D    +L+  + + + +A  L+    +LILD  T  +D
Sbjct: 631 --GYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALD 674


>X57522-1|CAA40741.1|  808|Homo sapiens peptide transporter protein.
          Length = 808

 Score = 35.1 bits (77), Expect = 1.0
 Identities = 37/166 (22%), Positives = 76/166 (45%), Gaps = 10/166 (6%)

Query: 212 PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS- 270
           P     LV+ GL+F ++ GE+ A++       + +  +L  + +   G ++++G+P+   
Sbjct: 573 PNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQY 632

Query: 271 --STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKP---RNTHSHVKMGDRDRINLLIE 325
               L + VA V  +  +    S++  + +    +KP     T + VK G    I+ L +
Sbjct: 633 EHRYLHRQVAAVGQEPQVF-GRSLQENIAY-GLTQKPTMEEITAAAVKSGAHSFISGLPQ 690

Query: 326 ELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
             G +   D    +L+  + + + +A  L+    +LILD  T  +D
Sbjct: 691 --GYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALD 734


>L21208-1|AAC12906.1|  748|Homo sapiens peptide transporter protein.
          Length = 748

 Score = 35.1 bits (77), Expect = 1.0
 Identities = 37/166 (22%), Positives = 76/166 (45%), Gaps = 10/166 (6%)

Query: 212 PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS- 270
           P     LV+ GL+F ++ GE+ A++       + +  +L  + +   G ++++G+P+   
Sbjct: 513 PNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQY 572

Query: 271 --STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKP---RNTHSHVKMGDRDRINLLIE 325
               L + VA V  +  +    S++  + +    +KP     T + VK G    I+ L +
Sbjct: 573 EHRYLHRQVAAVGQEPQVF-GRSLQENIAY-GLTQKPTMEEITAAAVKSGAHSFISGLPQ 630

Query: 326 ELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
             G +   D    +L+  + + + +A  L+    +LILD  T  +D
Sbjct: 631 --GYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALD 674


>L21204-1|AAC12902.1|  748|Homo sapiens peptide transporter protein.
          Length = 748

 Score = 35.1 bits (77), Expect = 1.0
 Identities = 37/166 (22%), Positives = 76/166 (45%), Gaps = 10/166 (6%)

Query: 212 PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS- 270
           P     LV+ GL+F ++ GE+ A++       + +  +L  + +   G ++++G+P+   
Sbjct: 513 PNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQY 572

Query: 271 --STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKP---RNTHSHVKMGDRDRINLLIE 325
               L + VA V  +  +    S++  + +    +KP     T + VK G    I+ L +
Sbjct: 573 EHRYLHRQVAAVGQEPQVF-GRSLQENIAY-GLTQKPTMEEITAAAVKSGAHSFISGLPQ 630

Query: 326 ELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
             G +   D    +L+  + + + +A  L+    +LILD  T  +D
Sbjct: 631 --GYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALD 674


>BX088556-4|CAM26263.1|  808|Homo sapiens transporter 1 ATP-binding
           cassette sub-family B (MDR/TAP) protein.
          Length = 808

 Score = 35.1 bits (77), Expect = 1.0
 Identities = 37/166 (22%), Positives = 76/166 (45%), Gaps = 10/166 (6%)

Query: 212 PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS- 270
           P     LV+ GL+F ++ GE+ A++       + +  +L  + +   G ++++G+P+   
Sbjct: 573 PNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQY 632

Query: 271 --STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKP---RNTHSHVKMGDRDRINLLIE 325
               L + VA V  +  +    S++  + +    +KP     T + VK G    I+ L +
Sbjct: 633 EHRYLHRQVAAVGQEPQVF-GRSLQENIAY-GLTQKPTMEEITAAAVKSGAHSFISGLPQ 690

Query: 326 ELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
             G +   D    +L+  + + + +A  L+    +LILD  T  +D
Sbjct: 691 --GYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALD 734


>BC014081-1|AAH14081.1|  808|Homo sapiens transporter 1, ATP-binding
           cassette, sub-family B (MDR/TAP) protein.
          Length = 808

 Score = 35.1 bits (77), Expect = 1.0
 Identities = 37/166 (22%), Positives = 76/166 (45%), Gaps = 10/166 (6%)

Query: 212 PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS- 270
           P     LV+ GL+F ++ GE+ A++       + +  +L  + +   G ++++G+P+   
Sbjct: 573 PNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQY 632

Query: 271 --STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKP---RNTHSHVKMGDRDRINLLIE 325
               L + VA V  +  +    S++  + +    +KP     T + VK G    I+ L +
Sbjct: 633 EHRYLHRQVAAVGQEPQVF-GRSLQENIAY-GLTQKPTMEEITAAAVKSGAHSFISGLPQ 690

Query: 326 ELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
             G +   D    +L+  + + + +A  L+    +LILD  T  +D
Sbjct: 691 --GYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALD 734


>AY196326-1|AAO40749.1|  930|Homo sapiens truncated ABCC12 protein
           protein.
          Length = 930

 Score = 35.1 bits (77), Expect = 1.0
 Identities = 49/223 (21%), Positives = 88/223 (39%), Gaps = 20/223 (8%)

Query: 210 TSPENKSTL---VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQ 266
           T PE +S     V+  +SF V+ G+IL +        + LL  L G  +   G + +NG 
Sbjct: 425 TGPEEQSDSLKSVLHSISFVVRKGKILGICGNVGSGKSSLLAALLGQMQLQKGVVAVNG- 483

Query: 267 PVASSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMG-DRDRINLLIE 325
                     +AYV +  A     +V   + F       R  H+    G  +D  NL   
Sbjct: 484 ---------TLAYV-SQQAWIFHGNVRENILFGEKYDHQRYQHTVRVCGLQKDLSNLPYG 533

Query: 326 ELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNW 385
           +L     R  N   L+  + +R+++A  +  D  + +LD P   +D      + E     
Sbjct: 534 DLTEIGERGLN---LSGGQRQRISLARAVYSDRQLYLLDDPLSAVDAHVGKHVFEECIKK 590

Query: 386 ASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDML 428
              G+ V++  H    +      +V+L+  G     G  ++++
Sbjct: 591 TLRGKTVVLVTH--QLQFLESCDEVILLEDGEICEKGTHKELM 631


>AY040220-1|AAK76740.1| 1359|Homo sapiens ATP-binding cassette
           transporter sub-family C member 12 protein.
          Length = 1359

 Score = 35.1 bits (77), Expect = 1.0
 Identities = 49/223 (21%), Positives = 88/223 (39%), Gaps = 20/223 (8%)

Query: 210 TSPENKSTL---VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQ 266
           T PE +S     V+  +SF V+ G+IL +        + LL  L G  +   G + +NG 
Sbjct: 483 TGPEEQSDSLKSVLHSISFVVRKGKILGICGNVGSGKSSLLAALLGQMQLQKGVVAVNG- 541

Query: 267 PVASSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMG-DRDRINLLIE 325
                     +AYV +  A     +V   + F       R  H+    G  +D  NL   
Sbjct: 542 ---------TLAYV-SQQAWIFHGNVRENILFGEKYDHQRYQHTVRVCGLQKDLSNLPYG 591

Query: 326 ELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNW 385
           +L     R  N   L+  + +R+++A  +  D  + +LD P   +D      + E     
Sbjct: 592 DLTEIGERGLN---LSGGQRQRISLARAVYSDRQLYLLDDPLSAVDAHVGKHVFEECIKK 648

Query: 386 ASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDML 428
              G+ V++  H    +      +V+L+  G     G  ++++
Sbjct: 649 TLRGKTVVLVTH--QLQFLESCDEVILLEDGEICEKGTHKELM 689


>AL935043-6|CAI18626.1|  808|Homo sapiens transporter 1, ATP-binding
           cassette, sub-family Bpha protein.
          Length = 808

 Score = 35.1 bits (77), Expect = 1.0
 Identities = 37/166 (22%), Positives = 76/166 (45%), Gaps = 10/166 (6%)

Query: 212 PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS- 270
           P     LV+ GL+F ++ GE+ A++       + +  +L  + +   G ++++G+P+   
Sbjct: 573 PNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQY 632

Query: 271 --STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKP---RNTHSHVKMGDRDRINLLIE 325
               L + VA V  +  +    S++  + +    +KP     T + VK G    I+ L +
Sbjct: 633 EHRYLHRQVAAVGQEPQVF-GRSLQENIAY-GLTQKPTMEEITAAAVKSGAHSFISGLPQ 690

Query: 326 ELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
             G +   D    +L+  + + + +A  L+    +LILD  T  +D
Sbjct: 691 --GYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALD 734


>AL671681-12|CAI17714.1|  808|Homo sapiens transporter 1,
           ATP-binding cassette, sub-family Be, 9 (large
           multifunctional pe protein.
          Length = 808

 Score = 35.1 bits (77), Expect = 1.0
 Identities = 37/166 (22%), Positives = 76/166 (45%), Gaps = 10/166 (6%)

Query: 212 PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS- 270
           P     LV+ GL+F ++ GE+ A++       + +  +L  + +   G ++++G+P+   
Sbjct: 573 PNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQY 632

Query: 271 --STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKP---RNTHSHVKMGDRDRINLLIE 325
               L + VA V  +  +    S++  + +    +KP     T + VK G    I+ L +
Sbjct: 633 EHRYLHRQVAAVGQEPQVF-GRSLQENIAY-GLTQKPTMEEITAAAVKSGAHSFISGLPQ 690

Query: 326 ELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
             G +   D    +L+  + + + +A  L+    +LILD  T  +D
Sbjct: 691 --GYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALD 734


>AL669918-8|CAI18140.1|  808|Homo sapiens transporter 1, ATP-binding
           cassette, sub-family Bpha protein.
          Length = 808

 Score = 35.1 bits (77), Expect = 1.0
 Identities = 37/166 (22%), Positives = 76/166 (45%), Gaps = 10/166 (6%)

Query: 212 PENKSTLVVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVAS- 270
           P     LV+ GL+F ++ GE+ A++       + +  +L  + +   G ++++G+P+   
Sbjct: 573 PNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQY 632

Query: 271 --STLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKP---RNTHSHVKMGDRDRINLLIE 325
               L + VA V  +  +    S++  + +    +KP     T + VK G    I+ L +
Sbjct: 633 EHRYLHRQVAAVGQEPQVF-GRSLQENIAY-GLTQKPTMEEITAAAVKSGAHSFISGLPQ 690

Query: 326 ELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
             G +   D    +L+  + + + +A  L+    +LILD  T  +D
Sbjct: 691 --GYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALD 734


>AK058170-1|BAB71700.1|  364|Homo sapiens protein ( Homo sapiens
           cDNA FLJ25441 fis, clone TST08455. ).
          Length = 364

 Score = 35.1 bits (77), Expect = 1.0
 Identities = 35/152 (23%), Positives = 68/152 (44%), Gaps = 9/152 (5%)

Query: 223 LSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVI---NGQPVASSTLRKVVAY 279
           +SF VK GEIL +L       + ++++L G  +  SG + +   + +        K + Y
Sbjct: 41  ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDDSLKCMGY 100

Query: 280 VRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGR 339
                 L P  +++     + A++    + S +K    + I+ +   L L++     V +
Sbjct: 101 CPQINPLWPDTTLQEHFEIYGAVK--GMSASDMK----EVISRITHALDLKEHLQKTVKK 154

Query: 340 LTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
           L     R+L  A  +L +  I +LD+P+  MD
Sbjct: 155 LPAGIKRKLCFALSMLGNPQITLLDEPSTGMD 186


>AF411578-1|AAL99901.1| 1009|Homo sapiens ATP-binding cassette
           protein C12 isoform D protein.
          Length = 1009

 Score = 35.1 bits (77), Expect = 1.0
 Identities = 49/223 (21%), Positives = 88/223 (39%), Gaps = 20/223 (8%)

Query: 210 TSPENKSTL---VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQ 266
           T PE +S     V+  +SF V+ G+IL +        + LL  L G  +   G + +NG 
Sbjct: 483 TGPEEQSDSLKSVLHSISFVVRKGKILGICGNVGSGKSSLLAALLGQMQLQKGVVAVNG- 541

Query: 267 PVASSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMG-DRDRINLLIE 325
                     +AYV +  A     +V   + F       R  H+    G  +D  NL   
Sbjct: 542 ---------TLAYV-SQQAWIFHGNVRENILFGEKYDHQRYQHTVRVCGLQKDLSNLPYG 591

Query: 326 ELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNW 385
           +L     R  N   L+  + +R+++A  +  D  + +LD P   +D      + E     
Sbjct: 592 DLTEIGERGLN---LSGGQRQRISLARAVYSDRQLYLLDDPLSAVDAHVGKHVFEECIKK 648

Query: 386 ASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDML 428
              G+ V++  H    +      +V+L+  G     G  ++++
Sbjct: 649 TLRGKTVVLVTH--QLQFLESCDEVILLEDGEICEKGTHKELM 689


>AF411577-1|AAL99900.1| 1009|Homo sapiens ATP-binding cassette
           protein C12 isoform C-p1 protein.
          Length = 1009

 Score = 35.1 bits (77), Expect = 1.0
 Identities = 49/223 (21%), Positives = 88/223 (39%), Gaps = 20/223 (8%)

Query: 210 TSPENKSTL---VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQ 266
           T PE +S     V+  +SF V+ G+IL +        + LL  L G  +   G + +NG 
Sbjct: 483 TGPEEQSDSLKSVLHSISFVVRKGKILGICGNVGSGKSSLLAALLGQMQLQKGVVAVNG- 541

Query: 267 PVASSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMG-DRDRINLLIE 325
                     +AYV +  A     +V   + F       R  H+    G  +D  NL   
Sbjct: 542 ---------TLAYV-SQQAWIFHGNVRENILFGEKYDHQRYQHTVRVCGLQKDLSNLPYG 591

Query: 326 ELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNW 385
           +L     R  N   L+  + +R+++A  +  D  + +LD P   +D      + E     
Sbjct: 592 DLTEIGERGLN---LSGGQRQRISLARAVYSDRQLYLLDDPLSAVDAHVGKHVFEECIKK 648

Query: 386 ASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDML 428
              G+ V++  H    +      +V+L+  G     G  ++++
Sbjct: 649 TLRGKTVVLVTH--QLQFLESCDEVILLEDGEICEKGTHKELM 689


>AF395909-1|AAL79529.1|  935|Homo sapiens ATP-binding cassette
           protein C12 isoform B protein.
          Length = 935

 Score = 35.1 bits (77), Expect = 1.0
 Identities = 49/223 (21%), Positives = 88/223 (39%), Gaps = 20/223 (8%)

Query: 210 TSPENKSTL---VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQ 266
           T PE +S     V+  +SF V+ G+IL +        + LL  L G  +   G + +NG 
Sbjct: 483 TGPEEQSDSLKSVLHSISFVVRKGKILGICGNVGSGKSSLLAALLGQMQLQKGVVAVNG- 541

Query: 267 PVASSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMG-DRDRINLLIE 325
                     +AYV +  A     +V   + F       R  H+    G  +D  NL   
Sbjct: 542 ---------TLAYV-SQQAWIFHGNVRENILFGEKYDHQRYQHTVRVCGLQKDLSNLPYG 591

Query: 326 ELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNW 385
           +L     R  N   L+  + +R+++A  +  D  + +LD P   +D      + E     
Sbjct: 592 DLTEIGERGLN---LSGGQRQRISLARAVYSDRQLYLLDDPLSAVDAHVGKHVFEECIKK 648

Query: 386 ASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDML 428
              G+ V++  H    +      +V+L+  G     G  ++++
Sbjct: 649 TLRGKTVVLVTH--QLQFLESCDEVILLEDGEICEKGTHKELM 689


>AF395908-1|AAL79528.1| 1009|Homo sapiens ATP-binding cassette
           protein C12 isoform A protein.
          Length = 1009

 Score = 35.1 bits (77), Expect = 1.0
 Identities = 49/223 (21%), Positives = 88/223 (39%), Gaps = 20/223 (8%)

Query: 210 TSPENKSTL---VVSGLSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQ 266
           T PE +S     V+  +SF V+ G+IL +        + LL  L G  +   G + +NG 
Sbjct: 483 TGPEEQSDSLKSVLHSISFVVRKGKILGICGNVGSGKSSLLAALLGQMQLQKGVVAVNG- 541

Query: 267 PVASSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMG-DRDRINLLIE 325
                     +AYV +  A     +V   + F       R  H+    G  +D  NL   
Sbjct: 542 ---------TLAYV-SQQAWIFHGNVRENILFGEKYDHQRYQHTVRVCGLQKDLSNLPYG 591

Query: 326 ELGLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNW 385
           +L     R  N   L+  + +R+++A  +  D  + +LD P   +D      + E     
Sbjct: 592 DLTEIGERGLN---LSGGQRQRISLARAVYSDRQLYLLDDPLSAVDAHVGKHVFEECIKK 648

Query: 386 ASTGRVVIMSLHPPTYEIFAMLTKVVLISAGRTMFSGYRRDML 428
              G+ V++  H    +      +V+L+  G     G  ++++
Sbjct: 649 TLRGKTVVLVTH--QLQFLESCDEVILLEDGEICEKGTHKELM 689


>AB067475-1|BAB67781.1|  737|Homo sapiens KIAA1888 protein protein.
          Length = 737

 Score = 35.1 bits (77), Expect = 1.0
 Identities = 35/152 (23%), Positives = 68/152 (44%), Gaps = 9/152 (5%)

Query: 223 LSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVI---NGQPVASSTLRKVVAY 279
           +SF VK GEIL +L       + ++++L G  +  SG + +   + +        K + Y
Sbjct: 414 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDDSLKCMGY 473

Query: 280 VRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGR 339
                 L P  +++     + A++    + S +K    + I+ +   L L++     V +
Sbjct: 474 CPQINPLWPDTTLQEHFEIYGAVK--GMSASDMK----EVISRITHALDLKEHLQKTVKK 527

Query: 340 LTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
           L     R+L  A  +L +  I +LD+P+  MD
Sbjct: 528 LPAGIKRKLCFALSMLGNPQITLLDEPSTGMD 559


>AK056533-1|BAB71208.1|  865|Homo sapiens protein ( Homo sapiens
           cDNA FLJ31971 fis, clone NT2RP7008137, weakly similar to
           ATP-BINDING CASSETTE, SUB-FAMILY A, MEMBER 1. ).
          Length = 865

 Score = 34.7 bits (76), Expect = 1.3
 Identities = 36/152 (23%), Positives = 68/152 (44%), Gaps = 9/152 (5%)

Query: 223 LSFEVKCGEILAVLATAQHEATGLLDVLAGVRKKLSGDIVINGQPVASST---LRKVVAY 279
           +SF VK GEIL +L       + ++++L G  +  SG + +      +S      K + Y
Sbjct: 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCMGY 601

Query: 280 VRNDTALCPTMSVEHTLRFHAALRKPRNTHSHVKMGDRDRINLLIEELGLEQVRDTNVGR 339
                 L P  +++     + A++    + S +K    + I+ +   L L++     V +
Sbjct: 602 CPQINPLWPDTTLQEHFEIYGAVK--GMSASDMK----EVISRITHGLDLKEHLQKTVKK 655

Query: 340 LTRSEIRRLNVACQLLLDMAILILDQPTKEMD 371
           L     R+L  A  +L +  I +LD+P+  MD
Sbjct: 656 LPAGIKRKLCFALSMLGNPQITLLDEPSTGMD 687


>DQ413174-1|ABD83327.1|  650|Homo sapiens actin-binding LIM protein
           3 protein.
          Length = 650

 Score = 33.9 bits (74), Expect = 2.4
 Identities = 19/66 (28%), Positives = 29/66 (43%)

Query: 51  ETSSGYDSSDNETTANYNKYSRKYRSDPDFRMQNLQSTYQASTGVPLVAMHQAGIREPQW 110
           + S+   S  +E  +  +KYS  Y  DP +  ++   TY  S  VP      +G  E  +
Sbjct: 419 DLSTATKSKTSEDISQTSKYSPIYSPDPYYASESEYWTYHGSPKVPRARRFSSGGEEDDF 478

Query: 111 ANSRHK 116
             S HK
Sbjct: 479 DRSMHK 484


>BC001665-1|AAH01665.1|  544|Homo sapiens ABLIM3 protein protein.
          Length = 544

 Score = 33.9 bits (74), Expect = 2.4
 Identities = 19/66 (28%), Positives = 29/66 (43%)

Query: 51  ETSSGYDSSDNETTANYNKYSRKYRSDPDFRMQNLQSTYQASTGVPLVAMHQAGIREPQW 110
           + S+   S  +E  +  +KYS  Y  DP +  ++   TY  S  VP      +G  E  +
Sbjct: 341 DLSTATKSKTSEDISQTSKYSPIYSPDPYYASESEYWTYHGSPKVPRARRFSSGGEEDDF 400

Query: 111 ANSRHK 116
             S HK
Sbjct: 401 DRSMHK 406


>AK091270-1|BAC03623.1|  293|Homo sapiens protein ( Homo sapiens
           cDNA FLJ33951 fis, clone CTONG2018483, weakly similar to
           ATP-BINDING CASSETTE, SUB-FAMILY A, MEMBER 1. ).
          Length = 293

 Score = 33.9 bits (74), Expect = 2.4
 Identities = 37/149 (24%), Positives = 64/149 (42%), Gaps = 9/149 (6%)

Query: 269 ASSTLRKVVAYVRNDTALCPTMSVEHTLRFHAALRK-PRNTHSHVKMGDRDRINLLIEEL 327
           ++ T   ++ Y     AL   ++    L ++ +LR  PR     V  GD      LI  L
Sbjct: 27  SAGTAGVLIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVA-GD------LIRRL 79

Query: 328 GLEQVRDTNVGRLTRSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWAS 387
            LE   D  V   +    R+L+ A  L+    IL+LD+P+  MD     +L + +     
Sbjct: 80  HLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVR 139

Query: 388 TGRVVIMSLHPPTYEIFAMLTKVVLISAG 416
            G   +++ H    E  A+ T++ ++  G
Sbjct: 140 EGCAAVLTSH-SMEECEALCTRLAIMVNG 167


>AB020650-1|BAA74866.2|  691|Homo sapiens KIAA0843 protein protein.
          Length = 691

 Score = 33.9 bits (74), Expect = 2.4
 Identities = 19/66 (28%), Positives = 29/66 (43%)

Query: 51  ETSSGYDSSDNETTANYNKYSRKYRSDPDFRMQNLQSTYQASTGVPLVAMHQAGIREPQW 110
           + S+   S  +E  +  +KYS  Y  DP +  ++   TY  S  VP      +G  E  +
Sbjct: 460 DLSTATKSKTSEDISQTSKYSPIYSPDPYYASESEYWTYHGSPKVPRARRFSSGGEEDDF 519

Query: 111 ANSRHK 116
             S HK
Sbjct: 520 DRSMHK 525


>X76388-1|CAA53972.1|  599|Homo sapiens RNase L inhibitor protein.
          Length = 599

 Score = 32.7 bits (71), Expect = 5.4
 Identities = 39/176 (22%), Positives = 77/176 (43%), Gaps = 12/176 (6%)

Query: 230 GEILAVLATAQHEATGLLDVLAGVRKKLSG--DIVINGQPVAS----STLRKVVAYVRND 283
           GE+L ++ T     +  L +LAG +K   G  D   + Q + +    S L+     +  D
Sbjct: 103 GEVLGLVGTNGIGKSAALKILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILED 162

Query: 284 TALCPTMSVEHTLRFHAALRKPRNT-HSHVKMGDRDRINLLI-EELGLEQVRDTNVGRLT 341
             L   +  ++  RF   LR  + T  S +   D  +   ++ ++L L  +++ NV  L+
Sbjct: 163 D-LKAIIKPQYVARF---LRLAKGTVGSILDRKDETKTQAIVCQQLDLTHLKERNVEDLS 218

Query: 342 RSEIRRLNVACQLLLDMAILILDQPTKEMDIFDTFFLVEYLRNWASTGRVVIMSLH 397
             E++R   A   +    I + D+P+  +D+         +R+  +  R +I+  H
Sbjct: 219 GGELQRFACAVVCIQKADIFMFDEPSSYLDVKQRLKAAITIRSLINPDRYIIVVEH 274


>AL356504-1|CAI19595.1| 4061|Homo sapiens filaggrin protein.
          Length = 4061

 Score = 32.7 bits (71), Expect = 5.4
 Identities = 31/146 (21%), Positives = 52/146 (35%), Gaps = 5/146 (3%)

Query: 54  SGYDSSDNETTANYNKYSRKYRSDPDFRMQNLQSTYQASTGV--PLVAMHQAGIREPQWA 111
           +G+    ++ +A      R  RS       +     ++S G   P   + Q    E    
Sbjct: 768 AGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARD 827

Query: 112 NSRHKSVSEAN--LLGIDGRPQR-TQYTNRRNSVADFVPDGDHHSYLLPSSHLGGRMSKA 168
           NSRH +  +    + G  G  +R  Q ++   SV      G HHS+            ++
Sbjct: 828 NSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQS 887

Query: 169 GSHMSVAHSRKHSTLRPGDQLDGYAH 194
           GS  +   +R     R G +  G  H
Sbjct: 888 GSRSASRTTRNEEQSRDGSRHSGSRH 913


>BC009062-1|AAH09062.1|  198|Homo sapiens Unknown (protein for
           IMAGE:3875076) protein.
          Length = 198

 Score = 32.3 bits (70), Expect = 7.2
 Identities = 39/166 (23%), Positives = 58/166 (34%), Gaps = 8/166 (4%)

Query: 23  SGTPKPKTSIGSGMKP---VQRIHRQSRGVRETSSGYDSSDNETTANYNKYSRKYRSDPD 79
           S TP PK ++  G  P     +  R+S     +SS   SS + ++++ +  S    S   
Sbjct: 27  SPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 86

Query: 80  FRMQNLQSTYQASTGVPLVAMHQAGIREPQWANSRHKSVSEANLLGIDGRPQRTQYTNRR 139
               +  S   A  G P      A  ++P     R +S  +      D R        RR
Sbjct: 87  SSSSSSSSPSPAKPG-PQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERR 145

Query: 140 NSVADFVPDGDHHSYLLPSSHLGGRMSKAGSHMSVAHSRKHSTLRP 185
                  P     S    SS  G R  + G   S +H R+  T  P
Sbjct: 146 RPSPQPSPRDQQSS----SSERGSRRGQRGDSRSPSHKRRRETPSP 187


>AB016092-1|BAA83718.1| 2752|Homo sapiens RNA binding protein protein.
          Length = 2752

 Score = 32.3 bits (70), Expect = 7.2
 Identities = 39/166 (23%), Positives = 58/166 (34%), Gaps = 8/166 (4%)

Query: 23   SGTPKPKTSIGSGMKP---VQRIHRQSRGVRETSSGYDSSDNETTANYNKYSRKYRSDPD 79
            S TP PK ++  G  P     +  R+S     +SS   SS + ++++ +  S    S   
Sbjct: 2581 SPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2640

Query: 80   FRMQNLQSTYQASTGVPLVAMHQAGIREPQWANSRHKSVSEANLLGIDGRPQRTQYTNRR 139
                +  S   A  G P      A  ++P     R +S  +      D R        RR
Sbjct: 2641 SSSSSSSSPSPAKPG-PQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERR 2699

Query: 140  NSVADFVPDGDHHSYLLPSSHLGGRMSKAGSHMSVAHSRKHSTLRP 185
                   P     S    SS  G R  + G   S +H R+  T  P
Sbjct: 2700 RPSPQPSPRDQQSS----SSERGSRRGQRGDSRSPSHKRRRETPSP 2741


>AB016091-1|BAA83717.1| 1275|Homo sapiens RNA binding protein protein.
          Length = 1275

 Score = 32.3 bits (70), Expect = 7.2
 Identities = 39/166 (23%), Positives = 58/166 (34%), Gaps = 8/166 (4%)

Query: 23   SGTPKPKTSIGSGMKP---VQRIHRQSRGVRETSSGYDSSDNETTANYNKYSRKYRSDPD 79
            S TP PK ++  G  P     +  R+S     +SS   SS + ++++ +  S    S   
Sbjct: 1104 SPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 1163

Query: 80   FRMQNLQSTYQASTGVPLVAMHQAGIREPQWANSRHKSVSEANLLGIDGRPQRTQYTNRR 139
                +  S   A  G P      A  ++P     R +S  +      D R        RR
Sbjct: 1164 SSSSSSSSPSPAKPG-PQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERR 1222

Query: 140  NSVADFVPDGDHHSYLLPSSHLGGRMSKAGSHMSVAHSRKHSTLRP 185
                   P     S    SS  G R  + G   S +H R+  T  P
Sbjct: 1223 RPSPQPSPRDQQSS----SSERGSRRGQRGDSRSPSHKRRRETPSP 1264


>AB002322-1|BAA20782.3| 2800|Homo sapiens KIAA0324 protein protein.
          Length = 2800

 Score = 32.3 bits (70), Expect = 7.2
 Identities = 39/166 (23%), Positives = 58/166 (34%), Gaps = 8/166 (4%)

Query: 23   SGTPKPKTSIGSGMKP---VQRIHRQSRGVRETSSGYDSSDNETTANYNKYSRKYRSDPD 79
            S TP PK ++  G  P     +  R+S     +SS   SS + ++++ +  S    S   
Sbjct: 2629 SPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2688

Query: 80   FRMQNLQSTYQASTGVPLVAMHQAGIREPQWANSRHKSVSEANLLGIDGRPQRTQYTNRR 139
                +  S   A  G P      A  ++P     R +S  +      D R        RR
Sbjct: 2689 SSSSSSSSPSPAKPG-PQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERR 2747

Query: 140  NSVADFVPDGDHHSYLLPSSHLGGRMSKAGSHMSVAHSRKHSTLRP 185
                   P     S    SS  G R  + G   S +H R+  T  P
Sbjct: 2748 RPSPQPSPRDQQSS----SSERGSRRGQRGDSRSPSHKRRRETPSP 2789


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.322    0.136    0.408 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 116,094,384
Number of Sequences: 224733
Number of extensions: 4864226
Number of successful extensions: 16614
Number of sequences better than 10.0: 194
Number of HSP's better than 10.0 without gapping: 128
Number of HSP's successfully gapped in prelim test: 66
Number of HSP's that attempted gapping in prelim test: 16157
Number of HSP's gapped (non-prelim): 361
length of query: 823
length of database: 73,234,838
effective HSP length: 96
effective length of query: 727
effective length of database: 51,660,470
effective search space: 37557161690
effective search space used: 37557161690
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 69 (31.9 bits)

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