Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000209-TA|BGIBMGA000209-PA|IPR002212|Matrix
fibril-associated, IPR013091|EGF calcium-binding, IPR009030|Growth
factor, receptor, IPR000152|Aspartic acid and asparagine hydroxylation
site, IPR013032|EGF-like region, IPR000742|EGF-like, type 3,
IPR001881|EGF-like calcium-binding, IPR006210|EGF,
IPR001491|Thrombomodulin
(860 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein. 728 0.0
AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form ... 728 0.0
AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form ... 728 0.0
AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form ... 728 0.0
AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein. 728 0.0
AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein. 728 0.0
AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein. 728 0.0
AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein. 728 0.0
AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein. 720 0.0
X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein. 719 0.0
L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein. 719 0.0
AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital... 630 e-180
U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein. 622 e-177
AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant pro... 599 e-170
AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein. 450 e-126
S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growt... 445 e-124
BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming gro... 445 e-124
AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming gro... 445 e-124
Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein. 444 e-124
AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming gro... 412 e-114
AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming gro... 412 e-114
Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding p... 398 e-110
AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein. 386 e-106
AK131282-1|BAD18457.1| 872|Homo sapiens protein ( Homo sapiens ... 385 e-106
BC008761-1|AAH08761.2| 743|Homo sapiens LTBP3 protein protein. 384 e-106
AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming gro... 384 e-106
M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein. 377 e-104
BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming gro... 377 e-104
AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth fac... 377 e-104
AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming gro... 377 e-104
X62009-1|CAB56757.1| 754|Homo sapiens fibrillin 5 protein. 377 e-103
AC019127-1|AAY24260.1| 697|Homo sapiens unknown protein. 375 e-103
X62008-1|CAB56534.1| 517|Homo sapiens fibrillin 15 protein. 299 3e-80
AF054502-1|AAC39882.1| 669|Homo sapiens latent transforming gro... 285 3e-76
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 258 6e-68
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 258 6e-68
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 258 6e-68
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein. 258 6e-68
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein. 258 6e-68
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein. 257 1e-67
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein. 257 1e-67
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein. 257 1e-67
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl... 256 2e-67
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl... 256 2e-67
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va... 256 2e-67
AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein. 252 4e-66
AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein. 249 4e-65
AL117551-1|CAB55988.1| 511|Homo sapiens hypothetical protein pr... 243 2e-63
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. 240 2e-62
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. 240 2e-62
AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant... 237 9e-62
X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein. 234 9e-61
BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein. 234 9e-61
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 228 6e-59
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 228 6e-59
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 228 6e-59
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 228 6e-59
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 228 6e-59
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 228 6e-59
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 228 6e-59
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 228 6e-59
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 228 6e-59
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 228 7e-59
BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein. 225 4e-58
X53743-1|CAA37772.1| 683|Homo sapiens fibulin-1 C protein. 219 3e-56
BC022497-1|AAH22497.1| 683|Homo sapiens fibulin 1 protein. 219 3e-56
AF217999-1|AAG17241.1| 495|Homo sapiens unknown protein. 219 5e-56
X53742-1|CAA37771.1| 601|Homo sapiens fibulin-1 B protein. 218 8e-56
Z99756-1|CAI18854.1| 988|Homo sapiens protein ( Human DNA seque... 216 3e-55
Z82214-3|CAI21674.1| 988|Homo sapiens protein ( Human DNA seque... 216 3e-55
U01244-1|AAB17099.1| 703|Homo sapiens fibulin-1D protein. 216 3e-55
AF126110-1|AAK37822.1| 703|Homo sapiens fibulin-1 isoform D pre... 216 3e-55
Z98047-1|CAI19628.1| 703|Homo sapiens fibulin 1 protein. 215 4e-55
Z95331-3|CAI41717.1| 703|Homo sapiens fibulin 1 protein. 215 4e-55
AL021391-3|CAI18930.1| 703|Homo sapiens fibulin 1 protein. 215 4e-55
AK075566-1|BAC11705.1| 638|Homo sapiens protein ( Homo sapiens ... 215 4e-55
X53741-1|CAA37770.1| 566|Homo sapiens fibulin-1 A protein. 213 3e-54
BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein. 210 1e-53
AK027344-1|BAB55049.1| 741|Homo sapiens protein ( Homo sapiens ... 208 6e-53
AF525689-1|AAN77133.1| 988|Homo sapiens signal peptide-CUB-EGF-... 207 1e-52
Z97832-1|CAI20187.1| 993|Homo sapiens protein ( Human DNA seque... 206 3e-52
AY639608-1|AAU08347.1| 993|Homo sapiens signal peptide, CUB and... 206 3e-52
AF452494-1|AAN76808.1| 993|Homo sapiens CUB and EGF containing ... 206 3e-52
BC052263-1|AAH52263.2| 992|Homo sapiens signal peptide, CUB dom... 206 3e-52
U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jag... 202 3e-51
U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein. 202 3e-51
U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jag... 202 3e-51
BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille synd... 202 3e-51
BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille synd... 202 3e-51
BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille synd... 202 3e-51
AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille synd... 202 3e-51
AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein J... 202 3e-51
AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein. 202 6e-51
AK131552-1|BAD18686.1| 682|Homo sapiens protein ( Homo sapiens ... 197 1e-49
BC111690-1|AAI11691.1| 807|Homo sapiens SCUBE2 protein protein. 197 2e-49
AK123039-1|BAC85521.1| 971|Homo sapiens protein ( Homo sapiens ... 195 6e-49
AJ400877-1|CAB92285.1| 999|Homo sapiens CEGP1 protein protein. 195 6e-49
U69263-1|AAC51260.2| 956|Homo sapiens matrilin-2 precursor prot... 194 8e-49
BC016394-1|AAH16394.1| 715|Homo sapiens MATN2 protein protein. 194 1e-48
BC010444-1|AAH10444.1| 937|Homo sapiens matrilin 2 protein. 194 1e-48
AL833931-1|CAD38787.1| 1016|Homo sapiens hypothetical protein pr... 194 1e-48
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. 193 3e-48
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. 193 3e-48
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 193 3e-48
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 193 3e-48
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso... 193 3e-48
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop... 193 3e-48
D86566-1|BAA13116.1| 955|Homo sapiens notch related protein pro... 192 3e-48
AK074499-1|BAC11024.1| 636|Homo sapiens protein ( Homo sapiens ... 192 3e-48
Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein. 190 2e-47
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 189 3e-47
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso... 189 3e-47
AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein. 189 3e-47
AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein. 188 7e-47
AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein. 188 1e-46
AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein. 188 1e-46
AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein pr... 182 5e-45
AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein. 182 5e-45
AY358895-1|AAQ89254.1| 915|Homo sapiens MATN2 protein. 182 6e-45
AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein. 180 1e-44
DQ217942-1|ABB70739.1| 886|Homo sapiens EGF-like module contain... 180 2e-44
BC059395-1|AAH59395.1| 821|Homo sapiens EMR1 protein protein. 180 2e-44
AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domai... 180 2e-44
AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domai... 180 2e-44
AB065918-1|BAC06133.1| 929|Homo sapiens seven transmembrane hel... 180 2e-44
X81479-1|CAA57232.1| 886|Homo sapiens EMR1 protein. 178 8e-44
AF124486-1|AAG45245.1| 443|Homo sapiens fibulin-like extracellu... 172 5e-42
CR541934-1|CAG46732.1| 443|Homo sapiens EFEMP2 protein. 171 9e-42
BC010456-1|AAH10456.1| 443|Homo sapiens EGF-containing fibulin-... 171 9e-42
AY358899-1|AAQ89258.1| 443|Homo sapiens EFEMP2 protein. 171 9e-42
AJ132819-1|CAA10791.2| 443|Homo sapiens fibulin-4 protein. 171 9e-42
AF109121-1|AAF65188.1| 443|Homo sapiens EGF-containing fibulin-... 171 9e-42
AB030655-1|BAA92880.1| 443|Homo sapiens mutant p53 binding prot... 171 9e-42
CR457140-1|CAG33421.1| 448|Homo sapiens FBLN5 protein. 169 4e-41
BC022280-1|AAH22280.1| 448|Homo sapiens fibulin 5 protein. 169 4e-41
AJ133490-1|CAB38568.1| 448|Homo sapiens fibulin-5 protein. 169 4e-41
AF112152-1|AAD41768.1| 448|Homo sapiens developmental arteries ... 169 4e-41
U03877-1|AAA65590.1| 387|Homo sapiens extracellular protein pro... 169 5e-41
BC098561-1|AAH98561.1| 493|Homo sapiens EGF-containing fibulin-... 169 5e-41
BC014410-1|AAH14410.1| 493|Homo sapiens EGF-containing fibulin-... 169 5e-41
AY004330-1|AAK11491.1| 493|Homo sapiens EGF-containing fibulin-... 169 5e-41
AB209212-1|BAD92449.1| 418|Homo sapiens EGF-containing fibulin-... 169 5e-41
AY358898-1|AAQ89257.1| 448|Homo sapiens FBLN5 protein. 167 2e-40
AF093118-1|AAC62107.1| 448|Homo sapiens UP50 protein. 165 4e-40
AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive sequ... 163 2e-39
AC010895-1|AAY14669.1| 320|Homo sapiens unknown protein. 162 6e-39
AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein. 161 7e-39
AF093119-1|AAC62108.1| 439|Homo sapiens UPH1 protein. 157 2e-37
AF054501-1|AAC39881.1| 161|Homo sapiens latent transforming gro... 154 1e-36
AL133553-4|CAI17860.1| 240|Homo sapiens protein ( Human DNA seq... 153 2e-36
AK222891-1|BAD96611.1| 810|Homo sapiens egf-like module contain... 153 2e-36
AF114491-1|AAF21974.1| 823|Homo sapiens EGF-like module EMR2 pr... 153 2e-36
AB065931-1|BAC06146.1| 837|Homo sapiens seven transmembrane hel... 153 2e-36
AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein. 153 2e-36
BC127263-1|AAI27264.1| 363|Homo sapiens SCUBE1 protein protein. 152 4e-36
BC127005-1|AAI27006.1| 823|Homo sapiens egf-like module contain... 152 4e-36
BC127004-1|AAI27005.1| 823|Homo sapiens egf-like module contain... 152 4e-36
X94630-1|CAA64333.1| 835|Homo sapiens seven-span transmembrane ... 152 6e-36
U76764-1|AAB36682.1| 835|Homo sapiens CD97 protein. 152 6e-36
AK131562-1|BAD18695.1| 867|Homo sapiens protein ( Homo sapiens ... 152 6e-36
AB065966-1|BAC06178.1| 837|Homo sapiens seven transmembrane hel... 152 6e-36
D89629-1|BAB46925.1| 815|Homo sapiens cerebral protein-12 protein. 149 4e-35
D83018-1|BAA11681.1| 816|Homo sapiens nel-related protein 2 pro... 149 4e-35
BC020544-1|AAH20544.1| 816|Homo sapiens NELL2 protein protein. 149 4e-35
D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein. 146 2e-34
BC096102-1|AAH96102.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 146 2e-34
BC096101-1|AAH96101.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 146 2e-34
BC069674-1|AAH69674.1| 810|Homo sapiens nel-like 1, precursor p... 146 2e-34
U94333-1|AAB53110.1| 652|Homo sapiens C1qR(p) protein. 143 3e-33
BC028075-1|AAH28075.1| 652|Homo sapiens CD93 molecule protein. 143 3e-33
AY358336-1|AAQ88702.1| 509|Homo sapiens DFLL295 protein. 143 3e-33
AL118508-1|CAC00597.1| 652|Homo sapiens complement component 1,... 143 3e-33
AB209895-1|BAD93132.1| 671|Homo sapiens complement component 1,... 143 3e-33
AJ295142-1|CAC82720.1| 652|Homo sapiens C1q receptor protein pr... 141 8e-33
AC005327-1|AAC27673.1| 287|Homo sapiens CD97_HUMAN, partial CDS... 140 3e-32
AK027775-1|BAB55358.1| 537|Homo sapiens protein ( Homo sapiens ... 139 4e-32
U57523-1|AAB06946.1| 446|Homo sapiens protein ( Human nel homol... 136 2e-31
AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precurs... 134 2e-30
AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precurso... 134 2e-30
AL513325-3|CAH72584.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 134 2e-30
AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 134 2e-30
AL136322-4|CAI16646.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 134 2e-30
AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein. 134 2e-30
AK075489-1|BAC11648.1| 451|Homo sapiens rase 7. protein. 132 4e-30
BC038587-1|AAH38587.1| 553|Homo sapiens EGF-like-domain, multip... 131 1e-29
AY358333-1|AAQ88699.1| 338|Homo sapiens EGFL6 protein. 131 1e-29
AK092062-1|BAC03798.1| 880|Homo sapiens protein ( Homo sapiens ... 131 1e-29
AK075214-1|BAC11477.1| 553|Homo sapiens protein ( Homo sapiens ... 131 1e-29
AJ245671-1|CAB92132.1| 554|Homo sapiens hypothetical protein pr... 131 1e-29
AF186084-1|AAF27812.1| 553|Homo sapiens epidermal growth factor... 131 1e-29
AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2 p... 130 3e-29
AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 130 3e-29
AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 130 3e-29
AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 130 3e-29
AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 130 3e-29
AF193055-1|AAG22483.1| 474|Homo sapiens unknown protein. 128 1e-28
AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein. 126 3e-28
AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitami... 126 3e-28
AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12 re... 126 3e-28
Y00692-1|CAA68687.1| 676|Homo sapiens preproprotein S protein. 123 2e-27
M57853-1|AAA60357.1| 676|Homo sapiens S protein protein. 123 2e-27
M36564-1|AAA60180.1| 650|Homo sapiens PROS1 protein. 123 2e-27
M15036-1|AAA36479.1| 676|Homo sapiens protein ( Human vitamin K... 123 2e-27
BC015801-1|AAH15801.1| 676|Homo sapiens PROS1 protein protein. 123 2e-27
AY308744-1|AAP45054.1| 497|Homo sapiens protein S (alpha) protein. 123 2e-27
AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic fact... 123 2e-27
AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic fact... 123 2e-27
AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic fact... 123 2e-27
X12892-1|CAA31383.1| 650|Homo sapiens protein ( H.sapiens mRNA ... 123 3e-27
M14338-1|AAA60181.1| 650|Homo sapiens protein S precursor protein. 123 3e-27
AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein p... 122 7e-27
AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand f... 122 7e-27
AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand f... 122 7e-27
AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand f... 122 7e-27
AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens ... 122 7e-27
AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein. 122 7e-27
S54426-1|AAB25244.1| 109|Homo sapiens fibrillin protein. 120 2e-26
BC053933-1|AAH53933.1| 239|Homo sapiens EMR2 protein protein. 120 2e-26
BC047916-1|AAH47916.1| 347|Homo sapiens SCUBE1 protein protein. 120 2e-26
BC034949-1|AAH34949.1| 239|Homo sapiens EMR2 protein protein. 120 2e-26
L13720-1|AAA58494.1| 678|Homo sapiens growth-arrest-specific pr... 120 3e-26
BX072579-3|CAH71174.1| 678|Homo sapiens growth arrest-specific ... 120 3e-26
BC038984-1|AAH38984.1| 678|Homo sapiens growth arrest-specific ... 120 3e-26
AY256843-1|AAO84057.1| 678|Homo sapiens growth arrested-specifi... 120 3e-26
AK126533-1|BAC86580.1| 624|Homo sapiens protein ( Homo sapiens ... 120 3e-26
AC013451-1|AAF87081.1| 969|Homo sapiens LTBP-2 protein. 119 4e-26
AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein. 117 2e-25
AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein. 117 2e-25
AK056571-1|BAB71219.1| 955|Homo sapiens protein ( Homo sapiens ... 116 4e-25
AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein pr... 115 8e-25
AB208923-1|BAD92160.1| 441|Homo sapiens crumbs homolog 1 isofor... 114 1e-24
U77493-1|AAB19224.1| 263|Homo sapiens Notch2 protein. 114 1e-24
AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein. 114 1e-24
AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophil... 114 1e-24
M16552-1|AAB59508.1| 575|Homo sapiens THBD protein. 111 1e-23
J02973-1|AAA61175.1| 575|Homo sapiens THBD protein. 111 1e-23
BC053357-1|AAH53357.1| 575|Homo sapiens thrombomodulin protein. 111 1e-23
AL049651-2|CAB51954.1| 575|Homo sapiens thrombomodulin protein. 111 1e-23
AF495471-1|AAM03232.1| 575|Homo sapiens thrombomodulin protein. 111 1e-23
X05495-1|CAA29045.1| 575|Homo sapiens thrombomodulin protein. 110 2e-23
D00210-1|BAA00149.1| 575|Homo sapiens thrombomodulin precursor ... 110 2e-23
BC035602-1|AAH35602.2| 575|Homo sapiens thrombomodulin protein. 110 2e-23
AL513325-2|CAM17208.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 105 5e-22
AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 105 5e-22
AL136322-3|CAM23328.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 105 5e-22
AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1 (alt... 105 5e-22
BC096103-1|AAH96103.1| 763|Homo sapiens NELL1 protein protein. 105 7e-22
BC096100-1|AAH96100.1| 763|Homo sapiens NELL1 protein protein. 105 7e-22
BC035784-1|AAH35784.1| 439|Homo sapiens hypothetical protein FL... 105 7e-22
AK094759-1|BAC04416.1| 439|Homo sapiens protein ( Homo sapiens ... 105 7e-22
AC092645-2|AAY14854.1| 439|Homo sapiens unknown protein. 105 7e-22
D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein pro... 105 9e-22
BC024766-1|AAH24766.2| 454|Homo sapiens DNER protein protein. 105 9e-22
AY358891-1|AAQ89250.1| 737|Homo sapiens QPRR262 protein. 105 9e-22
AF442487-1|AAM21557.1| 737|Homo sapiens delta-notch-like EGF re... 105 9e-22
BC035009-1|AAH35009.1| 737|Homo sapiens delta/notch-like EGF re... 104 2e-21
Y13341-1|CAA73785.1| 310|Homo sapiens matrilin-3 precursor prot... 102 5e-21
BC139907-1|AAI39908.1| 486|Homo sapiens matrilin 3 protein. 102 5e-21
AL021578-1|CAB46380.1| 622|Homo sapiens matrilin 4 protein. 102 5e-21
AJ224741-1|CAA12110.1| 486|Homo sapiens matrilin-3 protein. 102 5e-21
AJ001047-1|CAA04501.1| 303|Homo sapiens Matrilin-3 protein. 102 5e-21
AC079145-2|AAX88937.1| 486|Homo sapiens unknown protein. 102 5e-21
D86425-1|BAA13087.1| 1376|Homo sapiens osteonidogen protein. 102 6e-21
AJ223500-1|CAA11418.1| 1375|Homo sapiens nidogen-2 protein. 102 6e-21
AB009799-1|BAA24112.1| 1376|Homo sapiens osteonidogen protein. 102 6e-21
BC126986-1|AAI26987.1| 393|Homo sapiens FLJ37440 protein protein. 101 8e-21
AL021578-2|CAI21077.1| 432|Homo sapiens matrilin 4 protein. 101 1e-20
BC106950-1|AAI06951.1| 685|Homo sapiens delta-like 4 (Drosophil... 100 3e-20
AY358894-1|AAQ89253.1| 685|Homo sapiens DLL4 protein. 100 3e-20
AF279305-1|AAF81912.1| 653|Homo sapiens delta 4 protein. 100 3e-20
AF253468-1|AAF76427.1| 685|Homo sapiens notch ligand DLL4 protein. 100 3e-20
AC019195-1|AAY14953.1| 546|Homo sapiens unknown protein. 100 3e-20
AB043894-1|BAB18581.1| 685|Homo sapiens Delta-4 protein. 100 3e-20
AB036931-1|BAB16085.1| 685|Homo sapiens notch ligand delta-2 pr... 100 3e-20
BC035608-1|AAH35608.1| 969|Homo sapiens NID2 protein protein. 99 3e-20
AY265357-1|AAP88585.1| 4655|Homo sapiens glycoprotein receptor g... 99 6e-20
AB209121-1|BAD92358.1| 620|Homo sapiens Mutant p53 binding prot... 99 6e-20
M17778-1|AAA36799.1| 640|Homo sapiens protein ( Human uromoduli... 99 8e-20
M15881-1|AAA36798.1| 640|Homo sapiens protein ( Human uromoduli... 99 8e-20
BC035975-1|AAH35975.1| 611|Homo sapiens UMOD protein protein. 99 8e-20
AY162970-1|AAO64446.1| 640|Homo sapiens uromodulin precursor pr... 99 8e-20
BC050456-1|AAH50456.1| 961|Homo sapiens thrombospondin 4 protein. 97 2e-19
AY566253-1|AAS66982.1| 961|Homo sapiens thrombospondin 4 protein. 97 2e-19
Z19585-1|CAA79635.1| 961|Homo sapiens thrombospondin-4 protein. 97 2e-19
X82245-1|CAA57709.1| 1246|Homo sapiens nidogen protein. 97 3e-19
M30269-1|AAA59932.1| 1247|Homo sapiens nidogen protein. 97 3e-19
M27445-1|AAA57261.1| 581|Homo sapiens nidogen protein. 97 3e-19
AL139161-2|CAI23422.1| 1247|Homo sapiens nidogen 1 protein. 97 3e-19
AL122018-2|CAI22681.1| 1247|Homo sapiens nidogen 1 protein. 97 3e-19
BC126313-1|AAI26314.1| 1044|Homo sapiens MEGF11 protein protein. 96 5e-19
BC117419-1|AAI17420.1| 1044|Homo sapiens MEGF11 protein protein. 96 5e-19
AB209448-1|BAD92685.1| 1241|Homo sapiens nidogen (enactin) varia... 96 5e-19
AB058677-1|BAB47410.1| 969|Homo sapiens MEGF11 protein (KIAA178... 96 5e-19
U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein. 94 2e-18
AY265358-1|AAP88586.1| 4655|Homo sapiens glycoprotein receptor g... 94 2e-18
AK074396-1|BAB85069.1| 220|Homo sapiens protein ( Homo sapiens ... 94 2e-18
AC007556-2|AAX88965.1| 3881|Homo sapiens unknown protein. 94 2e-18
U04441-1|AAB02882.1| 1751|Homo sapiens glycoprotein 330 protein. 93 4e-18
X04571-1|CAA28240.1| 1207|Homo sapiens protein ( Human mRNA for ... 92 7e-18
BC113461-1|AAI13462.1| 1207|Homo sapiens epidermal growth factor... 92 7e-18
BC093731-1|AAH93731.1| 1207|Homo sapiens epidermal growth factor... 92 7e-18
BC000218-1|AAH00218.1| 618|Homo sapiens delta-like 3 (Drosophil... 92 7e-18
AY506357-1|AAR84237.1| 1152|Homo sapiens truncated epidermal gro... 92 7e-18
AF241373-1|AAF62542.1| 618|Homo sapiens DLL3 protein precursor ... 92 7e-18
AB231861-1|BAE19679.1| 1950|Homo sapiens low-density lipoprotein... 92 7e-18
AB084910-1|BAD83615.1| 1905|Homo sapiens low density lipoprotein... 92 7e-18
AL662849-16|CAI17471.1| 4222|Homo sapiens tenascin XB protein. 91 2e-17
AL662828-1|CAI17414.1| 4222|Homo sapiens tenascin XB protein. 91 2e-17
AL049547-2|CAB89296.1| 4288|Homo sapiens dJ34F7.1.1 (tenascin XB... 91 2e-17
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein... 91 2e-17
AC008273-1|AAF19247.2| 291|Homo sapiens unknown protein. 91 2e-17
X71923-1|CAA50739.1| 750|Homo sapiens tenascin-X precursor prot... 90 4e-17
U89337-3|AAB47488.1| 4289|Homo sapiens tenascin X protein. 90 4e-17
AL772248-1|CAI18078.1| 4222|Homo sapiens tenascin XB protein. 90 4e-17
AL662884-1|CAI18332.1| 4222|Homo sapiens tenascin XB protein. 90 4e-17
AL645922-1|CAI41718.1| 4222|Homo sapiens tenascin XB protein. 90 4e-17
AK075302-1|BAC11535.1| 587|Homo sapiens protein ( Homo sapiens ... 90 4e-17
BC126440-1|AAI26441.1| 321|Homo sapiens OIT3 protein protein. 89 5e-17
AY358339-1|AAQ88705.1| 545|Homo sapiens PPFL826 protein. 89 5e-17
AY013707-1|AAG40096.2| 545|Homo sapiens LZP protein. 89 5e-17
AK096435-1|BAC04788.1| 545|Homo sapiens protein ( Homo sapiens ... 89 5e-17
BC077719-1|AAH77719.1| 219|Homo sapiens VWCE protein protein. 89 8e-17
BC052564-1|AAH52564.1| 219|Homo sapiens VWCE protein protein. 89 8e-17
BC042143-1|AAH42143.1| 237|Homo sapiens VWCE protein protein. 89 8e-17
AL834326-1|CAD38994.1| 626|Homo sapiens hypothetical protein pr... 89 8e-17
BC090943-1|AAH90943.1| 249|Homo sapiens NOTCH2NL protein protein. 87 2e-16
BC084572-1|AAH84572.1| 343|Homo sapiens NOTCH2NL protein protein. 87 3e-16
AK075065-1|BAC11381.1| 269|Homo sapiens protein ( Homo sapiens ... 87 3e-16
S73849-1|AAB31735.1| 873|Homo sapiens very low density lipoprot... 86 4e-16
L22431-1|AAA61344.1| 873|Homo sapiens very low density lipoprot... 86 4e-16
D16532-1|BAA03969.1| 873|Homo sapiens very low density lipoprot... 86 4e-16
D16494-1|BAA03946.1| 845|Homo sapiens very low density lipoprot... 86 4e-16
D16493-1|BAA03945.1| 873|Homo sapiens very low density lipoprot... 86 4e-16
DQ067198-1|AAY46157.1| 873|Homo sapiens very low density lipopr... 86 4e-16
AL450467-4|CAH72455.1| 845|Homo sapiens very low density lipopr... 86 4e-16
AL450467-3|CAH72454.1| 873|Homo sapiens very low density lipopr... 86 4e-16
AB208822-1|BAD92059.1| 555|Homo sapiens Very low-density lipopr... 86 4e-16
AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA178... 86 4e-16
AC093039-1|AAX88911.1| 425|Homo sapiens unknown protein. 85 1e-15
D87433-1|BAA13377.2| 2589|Homo sapiens KIAA0246 protein protein. 85 1e-15
DQ786774-1|ABG91068.1| 2570|Homo sapiens FEX1 protein. 85 1e-15
AJ275213-1|CAB61827.1| 2570|Homo sapiens stabilin-1 protein. 85 1e-15
AB052956-1|BAC15606.1| 2570|Homo sapiens FELE-1 protein. 85 1e-15
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 84 2e-15
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 84 2e-15
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 84 2e-15
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 84 2e-15
L20470-1|AAA53684.1| 873|Homo sapiens very low density lipoprot... 84 2e-15
AF283408-1|AAL38109.1| 1537|Homo sapiens candidate tumor suppres... 84 2e-15
BC038242-1|AAH38242.1| 261|Homo sapiens Similar to RIKEN cDNA 1... 83 3e-15
BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein. 83 5e-15
BC065219-1|AAH65219.2| 236|Homo sapiens Notch homolog 2 (Drosop... 82 7e-15
BC019835-1|AAH19835.1| 236|Homo sapiens Notch homolog 2 N-termi... 82 7e-15
AB011540-1|BAA32468.1| 1576|Homo sapiens MEGF7 protein. 82 7e-15
BC131763-1|AAI31764.1| 581|Homo sapiens matrilin 4 protein. 82 9e-15
AL021578-3|CAB39280.1| 581|Homo sapiens matrilin 4 protein. 82 9e-15
AJ007581-1|CAA07569.1| 581|Homo sapiens matrilin-4 protein. 82 9e-15
BC014015-1|AAH14015.1| 383|Homo sapiens delta-like 1 homolog (D... 81 1e-14
BC007741-1|AAH07741.1| 383|Homo sapiens delta-like 1 homolog (D... 81 1e-14
AL592307-2|CAH73994.1| 230|Homo sapiens Notch homolog 2 (Drosop... 81 1e-14
U15979-1|AAA75364.1| 382|Homo sapiens dlk protein. 81 2e-14
BX537434-1|CAD97676.1| 236|Homo sapiens hypothetical protein pr... 81 2e-14
BC050675-1|AAH50675.1| 353|Homo sapiens cysteine-rich with EGF-... 81 2e-14
BC010154-1|AAH10154.3| 236|Homo sapiens Notch homolog 2 (Drosop... 81 2e-14
AL592307-1|CAH73993.1| 236|Homo sapiens Notch homolog 2 (Drosop... 81 2e-14
AL450467-2|CAH72453.1| 752|Homo sapiens very low density lipopr... 81 2e-14
AK092381-1|BAC03874.1| 752|Homo sapiens protein ( Homo sapiens ... 81 2e-14
DQ470680-1|ABF06672.1| 373|Homo sapiens CRELD2-zeta protein. 81 2e-14
BC013197-1|AAH13197.1| 383|Homo sapiens delta-like 1 homolog (D... 81 2e-14
AL137007-1|CAC10575.2| 199|Homo sapiens novel EGF-like domain c... 81 2e-14
L00352-1|AAA56833.1| 860|Homo sapiens low density lipoprotein r... 80 4e-14
DQ470678-1|ABF06670.1| 353|Homo sapiens CRELD2-delta protein. 80 4e-14
BT007361-1|AAP36025.1| 860|Homo sapiens low density lipoprotein... 80 4e-14
BC014514-1|AAH14514.1| 860|Homo sapiens low density lipoprotein... 80 4e-14
AY358355-1|AAQ88721.1| 353|Homo sapiens RLPR185 protein. 80 4e-14
AY324609-1|AAP72971.1| 860|Homo sapiens low density lipoprotein... 80 4e-14
AY114155-1|AAM56036.1| 860|Homo sapiens low density lipoprotein... 80 4e-14
AF217403-1|AAF24515.1| 837|Homo sapiens low density lipoprotein... 80 4e-14
AB209409-1|BAD92646.1| 870|Homo sapiens low density lipoprotein... 80 4e-14
X84700-1|CAA59173.1| 742|Homo sapiens leucocyte antigen CD97 pr... 79 5e-14
BC026690-1|AAH26690.1| 742|Homo sapiens CD97 molecule protein. 79 5e-14
Z12172-1|CAA78163.1| 383|Homo sapiens putative homeotic protein... 77 2e-13
BC051836-1|AAH51836.2| 904|Homo sapiens low density lipoprotein... 77 2e-13
D86407-1|BAA21824.1| 963|Homo sapiens ApoER2 protein. 77 3e-13
D50678-1|BAA09328.1| 963|Homo sapiens apolipoprotein E receptor... 77 3e-13
X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related prec... 77 4e-13
DQ470679-1|ABF06671.1| 402|Homo sapiens CRELD2-epsilon protein. 77 4e-13
DQ314873-1|ABC40732.1| 4544|Homo sapiens low density lipoprotein... 77 4e-13
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 77 4e-13
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 77 4e-13
AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 77 4e-13
AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 77 4e-13
AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-re... 77 4e-13
AB209498-1|BAD92735.1| 2359|Homo sapiens low density lipoprotein... 77 4e-13
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 77 4e-13
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 77 4e-13
AL606760-4|CAI18908.1| 963|Homo sapiens low density lipoprotein... 76 5e-13
AL606760-2|CAI18910.1| 904|Homo sapiens low density lipoprotein... 76 5e-13
AL359813-8|CAI23223.1| 377|Homo sapiens EGF-like-domain, multip... 76 5e-13
AL355483-2|CAI22780.1| 904|Homo sapiens low density lipoprotein... 76 5e-13
AL355483-1|CAI22781.1| 963|Homo sapiens low density lipoprotein... 76 5e-13
DQ470676-1|ABF06668.1| 321|Homo sapiens CRELD2-alpha protein. 76 6e-13
BX640729-1|CAE45845.1| 674|Homo sapiens hypothetical protein pr... 76 6e-13
BC002894-1|AAH02894.1| 321|Homo sapiens CRELD2 protein protein. 76 6e-13
AL136322-1|CAI16644.1| 674|Homo sapiens crumbs homolog 1 (Droso... 76 6e-13
BC105633-1|AAI05634.1| 757|Homo sapiens tumor endothelial marke... 75 8e-13
BC104484-1|AAI04485.1| 757|Homo sapiens tumor endothelial marke... 75 8e-13
BC060770-1|AAH60770.2| 757|Homo sapiens SUSD1 protein protein. 75 8e-13
BC051340-1|AAH51340.1| 757|Homo sapiens CD248 molecule, endosia... 75 8e-13
AY358746-1|AAQ89106.1| 747|Homo sapiens GRGP2438 protein. 75 8e-13
AL158824-3|CAI12348.2| 705|Homo sapiens sushi domain containing... 75 8e-13
AL158824-2|CAI12347.2| 747|Homo sapiens sushi domain containing... 75 8e-13
AL138756-2|CAI95300.2| 705|Homo sapiens sushi domain containing... 75 8e-13
AL138756-1|CAI95299.2| 747|Homo sapiens sushi domain containing... 75 8e-13
AJ295846-1|CAC34381.1| 757|Homo sapiens endosialin protein prot... 75 8e-13
AF279142-1|AAG00867.1| 757|Homo sapiens tumor endothelial marke... 75 8e-13
X56160-1|CAA39628.1| 2199|Homo sapiens tenascin protein. 75 1e-12
AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein... 75 1e-12
X55077-1|CAA38905.1| 591|Homo sapiens alpha-2 macroglobulin rec... 75 1e-12
D86407-2|BAA21825.1| 793|Homo sapiens ApoER2delta4-7 protein. 75 1e-12
CR457380-1|CAG33661.1| 422|Homo sapiens CRELD1 protein. 75 1e-12
AL356104-4|CAH72941.1| 1037|Homo sapiens novel protein similar t... 75 1e-12
AL158169-5|CAH70011.1| 1037|Homo sapiens novel protein similar t... 75 1e-12
AL162425-1|CAI15110.1| 2201|Homo sapiens tenascin C (hexabrachio... 74 2e-12
AB210038-1|BAE06120.1| 2233|Homo sapiens TNC variant protein pro... 74 2e-12
X78565-1|CAA55309.1| 2201|Homo sapiens human tenascin-C protein. 74 2e-12
M55618-1|AAA88083.1| 2203|Homo sapiens hexabrachion protein. 74 2e-12
U15981-1|AAA75365.1| 310|Homo sapiens dlk protein. 73 3e-12
AL606760-3|CAI18909.1| 700|Homo sapiens low density lipoprotein... 73 4e-12
AL355483-3|CAI22782.1| 700|Homo sapiens low density lipoprotein... 73 4e-12
AK160380-1|BAD18723.1| 1055|Homo sapiens FLJ00344 protein protein. 72 8e-12
BC008720-1|AAH08720.1| 422|Homo sapiens cysteine-rich with EGF-... 72 1e-11
AY358363-1|AAQ88729.1| 420|Homo sapiens CRELD1 protein. 72 1e-11
AF452623-1|AAM75206.1| 420|Homo sapiens cysteine-rich with EGF-... 72 1e-11
DQ126100-1|AAZ38943.1| 212|Homo sapiens brevideltin protein. 71 1e-11
DQ017081-1|AAY40461.1| 315|Homo sapiens secredeltin protein. 71 1e-11
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 71 2e-11
AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein. 71 2e-11
AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein. 71 2e-11
AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein. 71 2e-11
AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein. 71 2e-11
AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein. 71 2e-11
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 71 2e-11
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 71 2e-11
U77914-1|AAC50909.1| 263|Homo sapiens soluble protein Jagged pr... 71 2e-11
Z75190-1|CAA99509.1| 699|Homo sapiens apolipoprotein E receptor... 70 4e-11
L38969-1|AAC41762.1| 956|Homo sapiens thrombospondin 3 protein. 70 4e-11
BC113847-1|AAI13848.1| 956|Homo sapiens thrombospondin 3, precu... 70 4e-11
AL713999-15|CAI95084.1| 956|Homo sapiens thrombospondin 3 protein. 70 4e-11
AK223278-1|BAD96998.1| 956|Homo sapiens thrombospondin 3 precur... 70 4e-11
AF023268-6|AAC51818.1| 736|Homo sapiens thrombospondin3 protein. 70 4e-11
AY358347-1|AAQ88713.1| 406|Homo sapiens VPPP1921 protein. 69 5e-11
AF283342-1|AAL38107.1| 881|Homo sapiens candidate tumor suppres... 69 5e-11
AC068287-1|AAY24318.1| 223|Homo sapiens unknown protein. 69 5e-11
AB075863-1|BAB85569.1| 418|Homo sapiens KIAA1983 protein protein. 69 5e-11
AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ ... 69 7e-11
X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila F... 69 9e-11
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 68 1e-10
BC110320-1|AAI10321.1| 383|Homo sapiens EGF-like-domain, multip... 68 2e-10
AY358126-1|AAQ88493.1| 383|Homo sapiens PSGC2903 protein. 68 2e-10
AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for... 68 2e-10
AL359813-9|CAI23224.1| 383|Homo sapiens EGF-like-domain, multip... 68 2e-10
X14787-1|CAA32889.1| 1170|Homo sapiens precursor polypeptide (AA... 67 2e-10
X04665-1|CAA28370.1| 1170|Homo sapiens protein ( Human mRNA for ... 67 2e-10
DQ309460-1|ABC26875.1| 231|Homo sapiens delta-like 1 protein. 67 2e-10
AB209912-1|BAD93149.1| 1225|Homo sapiens thrombospondin 1 precur... 67 2e-10
BC027939-1|AAH27939.1| 600|Homo sapiens SNED1 protein protein. 67 3e-10
AC020594-1|AAY15036.1| 150|Homo sapiens unknown protein. 67 3e-10
AL359813-6|CAI23221.1| 288|Homo sapiens EGF-like-domain, multip... 66 4e-10
AB033063-1|BAA86551.2| 1268|Homo sapiens KIAA1237 protein protein. 66 5e-10
AC068195-1|AAX93243.1| 1126|Homo sapiens unknown protein. 66 7e-10
D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein. 65 9e-10
D86864-1|BAA24070.1| 830|Homo sapiens acetyl LDL receptor protein. 65 9e-10
D63483-1|BAA09770.1| 830|Homo sapiens KIAA0149 protein. 65 9e-10
BC039735-1|AAH39735.1| 830|Homo sapiens scavenger receptor clas... 65 9e-10
AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG seven... 65 9e-10
AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein. 65 9e-10
AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane hel... 65 9e-10
AB052948-1|BAC02694.1| 569|Homo sapiens SREC-3 protein. 65 9e-10
AB052946-1|BAC02692.1| 830|Homo sapiens SREC protein. 65 9e-10
L32137-1|AAA57253.1| 757|Homo sapiens matrix protein protein. 65 1e-09
BC125092-1|AAI25093.1| 757|Homo sapiens cartilage oligomeric ma... 65 1e-09
BC110847-1|AAI10848.1| 757|Homo sapiens cartilage oligomeric ma... 65 1e-09
BC072015-1|AAH72015.1| 296|Homo sapiens LRP1 protein protein. 65 1e-09
BC052593-1|AAH52593.1| 296|Homo sapiens LRP1 protein protein. 65 1e-09
BC045107-1|AAH45107.1| 292|Homo sapiens LRP1 protein protein. 65 1e-09
BC021204-1|AAH21204.1| 439|Homo sapiens LRP1 protein protein. 65 1e-09
AC003107-1|AAB86501.1| 817|Homo sapiens COMP_HUMAN protein. 65 1e-09
AB086984-1|BAC53888.1| 757|Homo sapiens cartilage oligomeric ma... 65 1e-09
AB076400-1|BAB86868.1| 1097|Homo sapiens fat3 protein. 64 2e-09
AK223216-1|BAD96936.1| 757|Homo sapiens cartilage oligomeric ma... 63 5e-09
AL137311-1|CAB70690.1| 252|Homo sapiens hypothetical protein pr... 62 6e-09
AL450324-2|CAI13283.1| 186|Homo sapiens protein ( Human DNA seq... 62 8e-09
BC133013-1|AAI33014.1| 594|Homo sapiens EGF-like-domain, multip... 61 1e-08
BC133011-1|AAI33012.1| 594|Homo sapiens EGF-like-domain, multip... 61 1e-08
AY358133-1|AAQ88500.1| 594|Homo sapiens TDKS9424 protein. 61 1e-08
AL589916-3|CAM13294.1| 594|Homo sapiens EGF-like-domain, multip... 61 1e-08
AL589916-2|CAI12363.2| 619|Homo sapiens EGF-like-domain, multip... 61 1e-08
AL365217-4|CAM23289.1| 594|Homo sapiens EGF-like-domain, multip... 61 1e-08
AL365217-3|CAI16606.1| 619|Homo sapiens EGF-like-domain, multip... 61 1e-08
>AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein.
Length = 2816
Score = 728 bits (1800), Expect = 0.0
Identities = 355/869 (40%), Positives = 460/869 (52%), Gaps = 64/869 (7%)
Query: 9 SCAGAVGVPQTKYLCCCS--VGHAWGAPCEACPPRGSPAHTALCGEK-PGEYINPVTNET 65
+C + T+ +CCCS +G AW PCEACP SP + LCG + PG + T +
Sbjct: 1667 TCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKP 1726
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ 125
IDEC +P +C G C + F+C C G+ +++ C DVDEC PC+ A
Sbjct: 1727 LDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1786
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCECKPGY-- 182
C+N+PG++ C+C GY+L+P C +EC + +C HGDC +T GSY C C G+
Sbjct: 1787 CINIPGSYRCKCTRGYKLSPG-GACVGQNECREIPNVCSHGDCMDTEGSYMCLCHRGFQA 1845
Query: 183 TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE-GGM 241
+ + +C D+DEC R +P C NGTC+N+ G+Y C C GF N DCVD +EC G
Sbjct: 1846 SADQTLCMDIDECDR-QP-CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1903
Query: 242 VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
VCR G C NT GSF C C G+ LTADG+NC D +EC L C G +C N G +
Sbjct: 1904 VCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTC-LPG--TCQNLEGSFR 1960
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER 361
C C G+++ C+D DEC E P +C G C N G + C CP G+ C D R
Sbjct: 1961 CICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTR 2020
Query: 362 KELCYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMRICQGGMG 419
+ C+ +EAG+C + + CCCS+ G WG CE CP SA F +C G G
Sbjct: 2021 QSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHG 2080
Query: 420 R----PNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
+ +D++EC P VC G CVNTDGSFRCECP GY L G++CVD DEC++
Sbjct: 2081 AVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG 2140
Query: 476 PRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
CG GTC+N GG+EC C+ GF G TC D+DEC+ C FRCHNT GS+ CTC
Sbjct: 2141 -HPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTC 2199
Query: 536 PYGYAVAADGVHCRDIDECVQEPRVCPHA----CENVVGSYICKCPEGYRRTSAPQDSEN 591
P GY + DG CRD+DEC + C HA C+N++G++ C CP G R P E
Sbjct: 2200 PAGYTLREDGAMCRDVDECADGQQDC-HARGMECKNLIGTFACVCPPGMR--PLPGSGE- 2255
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGR 651
C D NEC Q DLC G C+NT GSF CDCD GF+PS T+C D R G C+ ++
Sbjct: 2256 GCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTM 2315
Query: 652 CEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDL 711
C VT+A+CCC G WG CELCP PG+ A L
Sbjct: 2316 CR------------------SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKL 2357
Query: 712 CTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCAPGRFRCVCGPGY 771
C + A + CA + + G FRC C GY
Sbjct: 2358 CP--------------HGSGYTAEGRDVDECRMLAHL--CAHGECINSLGSFRCHCQAGY 2401
Query: 772 RP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDT 829
P C D+DEC+ P PC LC NT GS+ C C GY L+EDG C+D+DEC
Sbjct: 2402 TPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQ 2461
Query: 830 HTCQQICSNTEGSYECSCEDGYEKRGDAC 858
H CQ +C NT G++ C C G+ + AC
Sbjct: 2462 HNCQFLCVNTVGAFTCRCPPGFTQHHQAC 2490
Score = 458 bits (1129), Expect = e-128
Identities = 268/748 (35%), Positives = 343/748 (45%), Gaps = 83/748 (11%)
Query: 151 EDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTLR-ENVCRDVDECSRPRPVCRNGTCE 208
+ +D C +C +G C T SYRCEC GYT C DVDEC+ C +G C
Sbjct: 414 QTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSP--CHHGDCV 471
Query: 209 NLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTA 267
N+PG Y C C GF+A P CVDV+EC G +C GRC NT GSF+C C G+ L+
Sbjct: 472 NIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSP 531
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELP 325
DG+NC D +EC C N C N +G + C C G+ L G C+D DEC + P
Sbjct: 532 DGKNCVDHNEC-ATSTMCV---NGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDEC-QTP 586
Query: 326 YVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER-KELCYDEWEAGRCHRARPLQLAR 384
+C G C N G + C+C G VCVD + CY E G C R P + +
Sbjct: 587 GICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTK 646
Query: 385 PECCCSE-GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCV 443
ECCC+ +G C+ CPA +SAEF +C G+G +D++EC + P+VC G C
Sbjct: 647 SECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCE 706
Query: 444 NTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
N GS+RC C GY G C D DECAL+ +C NG C N+ G Y C C PGF
Sbjct: 707 NLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQ 766
Query: 504 D-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP 562
D + C DVDEC + C N AGS+ C C G + G C D + ++
Sbjct: 767 DTEICKDVDECLSS-PCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQE 825
Query: 563 HACE-NVVGSYI---CKCPEGYRRTSAPQDSE--------------NACEDINECEEQED 604
CE N+ G+ + C G S + E C+D+NECE
Sbjct: 826 SRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPG 885
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXX 664
+C G C+NT GSF C+C G G C+D R C+ C
Sbjct: 886 VCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDEC------------ 933
Query: 665 XXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXX 724
G CCC++GA WG ECE CP P S LC
Sbjct: 934 --------GVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCP----------- 974
Query: 725 XXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLC-------APGRFRCVCGPGYRPAGEV 777
+ DV+EC PGLC G F C C G+ +
Sbjct: 975 ----RGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQE 1030
Query: 778 --CADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD-EDGANCRDVDECERDTHTCQ 833
C D+DEC + P C Q C NT GS++C C GYE NC DVDEC RD C+
Sbjct: 1031 RNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCR 1090
Query: 834 -QICSNTEGSYECSCEDGYE--KRGDAC 858
C+NT+GSY+C C G+E +G AC
Sbjct: 1091 GGTCTNTDGSYKCQCPPGHELTAKGTAC 1118
Score = 442 bits (1089), Expect = e-123
Identities = 286/830 (34%), Positives = 359/830 (43%), Gaps = 101/830 (12%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+DEC P LC+ GTC +T ++C C G+E C D+DECS C QCV
Sbjct: 1079 VDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH-GQCV 1137
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
N+ GAF+C C G++ TP C D++EC Q C NT GSYRC C GY+L +
Sbjct: 1138 NVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPD 1197
Query: 188 --VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCR 244
C DVDEC VC G C N+PG + C C DGF A P+ CVDV+EC +C
Sbjct: 1198 GRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICL 1257
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
+G C NT GSF C C GY + C DVDEC+ H C D + SC N G + C C
Sbjct: 1258 HGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNC--DSHASCLNIPGSFSCRC 1315
Query: 305 GAGWKLVGRRCVDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
GW G C D DEC + C+ G+C N G Y C C G+ D DE E
Sbjct: 1316 LPGWVGDGFECHDLDECISQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAE 1375
Query: 364 --------LCYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMR- 412
C + RC C + A G C + R
Sbjct: 1376 NVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRC 1435
Query: 413 ICQGGM----GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
IC GG G N T D++EC P C+ G C+NT GS+ C CP + L P G+ CVD
Sbjct: 1436 ICNGGYELDRGGGNCT-DINEC-ADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVD 1493
Query: 469 --ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRA---SCTFR 523
A C L+ G+ G C G C C+ GRA C
Sbjct: 1494 TRAGNCFLETHDRGDS-------GISCSAEIGVGVTRASCC-----CSLGRAWGNPCELC 1541
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHC--RDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
+R CP G + + DIDEC + P +C C N GS+ C+CP GY
Sbjct: 1542 PMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGY 1601
Query: 581 RRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRT 640
+ + CEDI+EC +C G C NT G++ C C A + G +C+D R
Sbjct: 1602 HLS----EHTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRK 1657
Query: 641 GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCT--LGAAWGSECE 698
C+R +G C+ E +VT+ CCC+ +G AW CE
Sbjct: 1658 SVCFRH-YNGTCQNELAF--------------------NVTRKMCCCSYNIGQAWNRPCE 1696
Query: 699 LCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLC 758
CP P SP LC N P D+DEC IP +C
Sbjct: 1697 ACPTPISPDYQILCG--NQAPGFLTDIHTGKP---------------LDIDECGEIPAIC 1739
Query: 759 AP-------GRFRCVCGPG--YRPAGEVCADVDECAVRPPPCDQL--CHNTDGSYDCLCR 807
A G FRC C G Y C DVDEC R PC Q C N GSY C C
Sbjct: 1740 ANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCT 1799
Query: 808 TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
GY+L GA C +EC + C C +TEGSY C C G++ D
Sbjct: 1800 RGYKLSPGGA-CVGQNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASAD 1848
Score = 430 bits (1060), Expect = e-120
Identities = 232/592 (39%), Positives = 291/592 (49%), Gaps = 47/592 (7%)
Query: 1 MEWNEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
+ W+E++ C + +CCCS+G WG CEACP S +LC G
Sbjct: 926 LRWDEDE--CGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRD 983
Query: 61 VTNET---KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGR 117
+ K ++EC + P LC GTC +T F C C G+ D C D+DEC
Sbjct: 984 FLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISP 1043
Query: 118 PPCRGMAQCVNLPGAFECRCPPGYRLTPSL-DECEDVDECG-DQRICDHGDCRNTIGSYR 175
C G CVN PG+FEC C PGY L C DVDEC D +C G C NT GSY+
Sbjct: 1044 DLC-GQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYK 1102
Query: 176 CECKPGY--TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVD 232
C+C PG+ T + C D+DECS +C +G C N+ GA+ C C GF++ P+ CVD
Sbjct: 1103 CQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVD 1162
Query: 233 VNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
+NECR C + C NT GS+RC C GY+L DGR C DVDEC+E P C +
Sbjct: 1163 INECRVQNGGC-DVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQG---H 1218
Query: 293 CTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRF 350
CTN GG+ C C G+ R CVD DEC P++C G+C N G +VC C G+
Sbjct: 1219 CTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMV 1278
Query: 351 DKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
K A C D DE E G H C A+ C P S
Sbjct: 1279 RKGATGCSD------VDECEVGG-HN------------CDSHAS----CLNIPGSFSC-- 1313
Query: 411 MRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
R G +G DLDEC + C G C+N GS+RC C G+ A DG C D
Sbjct: 1314 -RCLPGWVGDGFECHDLDECISQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCEDR 1370
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTA 528
DECA + +C NG C N GGY C+C GF D + C DVDECA+G C N
Sbjct: 1371 DECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLP 1430
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGY 580
G FRC C GY + G +C DI+EC C N GSY+C CP+ +
Sbjct: 1431 GMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDF 1482
Score = 409 bits (1007), Expect = e-113
Identities = 300/917 (32%), Positives = 373/917 (40%), Gaps = 98/917 (10%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPID 69
C VG Q C V +PC P T C PG P +D
Sbjct: 440 CECNVGYTQDVRGECIDVDECTSSPCHHGDCVNIPG-TYHCRCYPGFQATPTRQACVDVD 498
Query: 70 ECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
EC + LC G C +T FQC C+ G+E C D +EC+ G+ C+N
Sbjct: 499 ECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGV--CLNE 556
Query: 130 PGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN-- 187
G+F C C PG+ L P C D+DEC IC +G C NT GS+RC+C G + +
Sbjct: 557 DGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGR 616
Query: 188 VCRDVD------------ECSRPRP--VCRNGTCENLPG------AYLCHCDDG--FKA- 224
VC D C+RP P V ++ C P LC + F+A
Sbjct: 617 VCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQAL 676
Query: 225 -----GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECD 279
G D D+NEC VC NG C N GS+RC C GY A G++C DVDEC
Sbjct: 677 CSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECA 736
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFN 337
C N C N+ G Y CSC G+ C D DEC P C G CRN
Sbjct: 737 LNSLLCD---NGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLA 791
Query: 338 GGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGR 397
G Y C+C G R D + C+D K C+ + + RC R ECC + GAAWG
Sbjct: 792 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGS 851
Query: 398 YCERCPAPDSAEFMRICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPD 455
CERC E C G R D++EC P VC GRCVNT GSFRCECP+
Sbjct: 852 PCERC------EIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPE 905
Query: 456 GYVLAPDGLSCVDA--DECAL--DPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDV 510
G +L G CVD + C L D CG R C CS G G + + C D
Sbjct: 906 GLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDV-CCCSIGAVWGVECEACPD- 963
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH-ACENVV 569
E E + C + F P+ +D++EC P +C H C N V
Sbjct: 964 PESLEFASLCPRGLGFASRDFLSGRPF----------YKDVNECKVFPGLCTHGTCRNTV 1013
Query: 570 GSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP- 628
GS+ C C G+ A E C DI+EC DLC G C+NT GSF C+C G+E
Sbjct: 1014 GSFHCACAGGF----ALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESG 1069
Query: 629 ----------SEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXG 678
E D + R GTC + S +C+ G
Sbjct: 1070 FMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDG 1129
Query: 679 HVTKAQCCCTLGAAWGS-ECELCPAPGSPARLDL--CTAVNLTPXXXXXXXXXXXXXXXX 735
QC +GA S P +D+ C N
Sbjct: 1130 LCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCG 1189
Query: 736 XXXXXXLD--VFADVDECAAIPGLC-------APGRFRCVCGPGY--RPAGEVCADVDEC 784
D ADVDEC P +C PG RC+C G+ P C DVDEC
Sbjct: 1190 QGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDEC 1249
Query: 785 AVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEG 841
+ P C C NT GS+ C C+ GY + + C DVDECE H C C N G
Sbjct: 1250 DLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPG 1309
Query: 842 SYECSCEDGYEKRGDAC 858
S+ C C G+ G C
Sbjct: 1310 SFSCRCLPGWVGDGFEC 1326
Score = 405 bits (996), Expect = e-112
Identities = 224/611 (36%), Positives = 293/611 (47%), Gaps = 53/611 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDE--------------- 112
IDEC P LC GTC ++P FQC C G+ + H C D +
Sbjct: 1977 IDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVP 2036
Query: 113 ---------CSWGRPPCRGMAQ-CVNLP----GAFECRCPPGYRLTPSLDEC-EDVDECG 157
C + P G C P AF+ CP G+ P D+ EDV+EC
Sbjct: 2037 KAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECA 2096
Query: 158 DQR-ICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAY 214
+ +C +G C NT GS+RCEC GY+L C D DECS P C GTC N+ G +
Sbjct: 2097 ENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP-CGQGTCTNVIGGF 2155
Query: 215 LCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRD 274
C C DGF+ G C D++EC ++C RC NT GS+ C C GYTL DG CRD
Sbjct: 2156 ECACADGFEPGLMMTCEDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRD 2214
Query: 275 VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV---GRRCVDRDECKELPYVCAGG 331
VDEC + C G C N G + C C G + + G C D +EC P +C G
Sbjct: 2215 VDECADGQQDCHARGM-ECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNG 2273
Query: 332 ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLA--RPECCC 389
C N G + C+C G++ T C D R+ C+ E C A R ECCC
Sbjct: 2274 RCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCC 2333
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
G WG CE CP P ++ + ++C G G +D+DECR+ +C G C+N+ GSF
Sbjct: 2334 GGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSF 2393
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCV 508
RC C GY +C+D DEC+ P+ C C NT+G + C C G+ D +TC
Sbjct: 2394 RCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCK 2452
Query: 509 DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC-PHA-CE 566
D+DEC + +C F C NT G+F C CP G+ C D DEC +P C H C
Sbjct: 2453 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQA--CFDNDECSAQPGPCGAHGHCH 2510
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
N GS+ C+C +G+ S S + CED+NEC+ C G C N G + C C GF
Sbjct: 2511 NTPGSFRCECHQGFTLVS----SGHGCEDVNECDGPH-RCQHG-CQNQLGGYRCSCPQGF 2564
Query: 627 EPSEDGTDCID 637
C+D
Sbjct: 2565 TQHSQWAQCVD 2575
Score = 394 bits (969), Expect = e-109
Identities = 285/874 (32%), Positives = 374/874 (42%), Gaps = 130/874 (14%)
Query: 21 YLCCCSVGHAW---GAPCEACPPRGSPAH--TALCGEKPGEYIN--PVTNETKP--IDEC 71
+ C C+ G+ G C P + +C PG Y+ P E P +
Sbjct: 1433 FRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCV 1492
Query: 72 DIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG 131
D C T +G C + G S C + +WG P C + N
Sbjct: 1493 DTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCC-SLGR-AWGNP-CE-LCPMANTT- 1547
Query: 132 AFECRCPPGYRLTPSLDEC--EDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTLREN- 187
+ CP G P+ ED+DEC + +C GDC NT GS++CEC PGY L E+
Sbjct: 1548 EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHT 1607
Query: 188 -VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF-KAGPNNDCVDVNECREGGMVC-- 243
+C D+DECS +C GTC N G Y C C + + N+C+D+ + VC
Sbjct: 1608 RICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKS-----VCFR 1662
Query: 244 -RNGRCRNTVGS--FRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGY 300
NG C+N + R C Y + C+ P P D C N G+
Sbjct: 1663 HYNGTCQNELAFNVTRKMCCCSYNIGQAWNR-----PCEACPTPISPDYQILCGNQAPGF 1717
Query: 301 ECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
G L D DEC E+P +CA G C N G + CECPAG+ ++ C D
Sbjct: 1718 LTDIHTGKPL------DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACED- 1770
Query: 361 RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGR 420
DE + R P Q +C G+ RC ++ GG
Sbjct: 1771 -----VDECGS----RESPCQ-QNADCINIPGSY------RCKCTRG---YKLSPGGA-- 1809
Query: 421 PNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG 480
+ECR P+VC G C++T+GS+ C C G+ + D C+D DEC P CG
Sbjct: 1810 ---CVGQNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQP--CG 1864
Query: 481 NGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAE--GRASCTF-RCHNTAGSFRCTCPY 537
NGTC N G Y C C PGF + CVD DEC G+ C F C NTAGSF C C
Sbjct: 1865 NGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQV-CRFGHCLNTAGSFHCLCQD 1923
Query: 538 GYAVAADGVHCRDIDECVQEPRVC-PHACENVVGSYICKCPEGYRRTSAPQDSENACEDI 596
G+ + ADG +C D +EC+ C P C+N+ GS+ C CP G+ Q + C DI
Sbjct: 1924 GFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGF------QVQSDHCIDI 1977
Query: 597 NECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEX 656
+EC E+ +LC G C N+ GSF C C GF S++G C D R C+ +G+C
Sbjct: 1978 DECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPK 2037
Query: 657 XXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTL--GAAWGSECELCPAPGSPARLDLCTA 714
+ TK +CCC+ G WG CELCP GS A +LC
Sbjct: 2038 AF--------------------NTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELC-- 2075
Query: 715 VNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCA-------PGRFRCVC 767
P D DV+ECA PG+C G FRC C
Sbjct: 2076 ----PFGHGAVPGPD-------------DSREDVNECAENPGVCTNGVCVNTDGSFRCEC 2118
Query: 768 GPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC 825
GY G C D DEC+V P C N G ++C C G+E C D+DEC
Sbjct: 2119 PFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLM-MTCEDIDEC 2177
Query: 826 ERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 859
+ C C NTEGSY C+C GY R D +
Sbjct: 2178 SLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAM 2211
Score = 380 bits (934), Expect = e-104
Identities = 219/596 (36%), Positives = 284/596 (47%), Gaps = 43/596 (7%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
CG+ G + P +DEC+ P++C G C + P G +C C G+ C D
Sbjct: 1188 CGQ--GYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVD 1245
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC--GDQRICDHGDC 167
VDEC C C N G+F C C GY + C DVDEC G H C
Sbjct: 1246 VDECDLNPHICLH-GDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASC 1304
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGP 226
N GS+ C C PG+ C D+DEC C G C N+PG+Y C C GF AG
Sbjct: 1305 LNIPGSFSCRCLPGWVGDGFECHDLDECISQEHRCSPRGDCLNVPGSYRCTCRQGF-AGD 1363
Query: 227 NNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C D +EC E +C NG+C N G +RCEC G+ T D R C+DVDEC + + C
Sbjct: 1364 GFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ-GNLCA 1422
Query: 287 RDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
SC N G + C C G++L G C D +EC + P C G C N G Y+C C
Sbjct: 1423 FG---SCENLPGMFRCICNGGYELDRGGGNCTDINECAD-PVNCINGVCINTPGSYLCSC 1478
Query: 345 PAGWRFDKTAAVCVDERKELCY----DEWEAG-RCHRARPLQLARPECCCSEGAAWGRYC 399
P + + + CVD R C+ D ++G C + + R CCCS G AWG C
Sbjct: 1479 PQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPC 1538
Query: 400 ERCPAPDSAEFMRICQGGMG-RPN----LTQDLDECRVRPDVCVGGRCVNTDGSFRCECP 454
E CP ++ E+ +C GG G +PN + +D+DEC+ P +C GG CVNT GSF+CECP
Sbjct: 1539 ELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECP 1598
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ-GPDQTCVDVDEC 513
GY L+ C D DEC+ ICG GTC NT G Y C C + Q C+D+
Sbjct: 1599 PGYHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDM--- 1655
Query: 514 AEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVG-S 571
R S FR +N C + V C +I + P C AC +
Sbjct: 1656 ---RKSVCFRHYNGT----CQNELAFNVTRKMCCCSYNIGQAWNRP--C-EACPTPISPD 1705
Query: 572 YICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
Y C G + D DI+EC E +C+ G+CIN GSF C+C AGF
Sbjct: 1706 YQILC--GNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGF 1759
Score = 372 bits (914), Expect = e-102
Identities = 242/661 (36%), Positives = 302/661 (45%), Gaps = 88/661 (13%)
Query: 11 AGAVGVPQ----TKYLCCCSV--GHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNE 64
AG VP+ TK CCCS G WG PCE CP GS A LC G P +
Sbjct: 2030 AGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGP-DDS 2088
Query: 65 TKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+ ++EC P +C G C +T F+C C GY D T C D DECS G P C G
Sbjct: 2089 REDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP-C-GQG 2146
Query: 125 QCVNLPGAFECRCPPGYRLTPSLD-ECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYT 183
C N+ G FEC C G+ P L CED+DEC + C NT GSY C C GYT
Sbjct: 2147 TCTNVIGGFECACADGFE--PGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYT 2204
Query: 184 LREN--VCRDVDECSRPRPVC--RNGTCENLPGAYLCHCDDGFKA--GPNNDCVDVNECR 237
LRE+ +CRDVDEC+ + C R C+NL G + C C G + G C D NEC
Sbjct: 2205 LREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECH 2264
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE-----------CDELPHP-- 284
+C NGRC NT GSFRC+C G+ + C D+ + C L
Sbjct: 2265 AQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSE 2324
Query: 285 --------CG--RDGNPSCTNT----NGGYE--CSCGAGWKLVGRRCVDRDECKELPYVC 328
CG R P C Y C G+G+ GR D DEC+ L ++C
Sbjct: 2325 AVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGR---DVDECRMLAHLC 2381
Query: 329 AGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECC 388
A GEC N G + C C AG+ D TA C+D DE C Q+ +P C
Sbjct: 2382 AHGECINSLGSFRCHCQAGYTPDATATTCLD------MDE-----CS-----QVPKP-CT 2424
Query: 389 CSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGS 448
G + CP E + G +DLDEC R C CVNT G+
Sbjct: 2425 FLCKNTKGSFLCSCPRGYLLE-----EDG----RTCKDLDECTSRQHNCQF-LCVNTVGA 2474
Query: 449 FRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQ-GPDQT 506
F C CP G+ +C D DEC+ P CG +G C NT G + C+C GFT
Sbjct: 2475 FTCRCPPGFTQHHQ--ACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHG 2532
Query: 507 CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-C 565
C DV+EC +G C C N G +RC+CP G+ + C D +EC P C A C
Sbjct: 2533 CEDVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASC 2591
Query: 566 ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
N +G + C CP G+ A C+D++EC + CS C NT G FLC C G
Sbjct: 2592 RNTLGGFRCVCPSGFDFDQAL----GGCQDVDECAGRRGPCSYS-CANTPGGFLCGCPQG 2646
Query: 626 F 626
+
Sbjct: 2647 Y 2647
Score = 356 bits (876), Expect = 2e-97
Identities = 213/603 (35%), Positives = 278/603 (46%), Gaps = 41/603 (6%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC LC G C + P G++C C+ G++ C+DVDEC+ G G C N
Sbjct: 1371 DECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFG--SCEN 1428
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENV 188
LPG F C C GY L C D++EC D C +G C NT GSY C C + L +
Sbjct: 1429 LPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1488
Query: 189 CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC 248
VD + C T + C + G + C + R G C
Sbjct: 1489 VGCVDTRAGN---CFLETHDRGDSGISCSAEIGVGVTRASCCCSLG--RAWGNPCELCPM 1543
Query: 249 RNTVGSFRCECAPGYTLTADGRNC--RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
NT +R C G + D+DEC ELP C + G+ C NT G ++C C
Sbjct: 1544 ANTT-EYRTLCPGGEGFQPNRITVILEDIDECQELPGLC-QGGD--CVNTFGSFQCECPP 1599
Query: 307 GWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKEL 364
G+ L R C D DEC +C G C N G Y C CPA + C+D RK +
Sbjct: 1600 GYHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSV 1659
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMRICQGGMGRPN 422
C+ + G C + R CCCS G AW R CE CP P S ++ +C G
Sbjct: 1660 CFRHYN-GTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILC-GNQAPGF 1717
Query: 423 LTQ-------DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
LT D+DEC P +C G C+N GSFRCECP G+ L+C D DEC
Sbjct: 1718 LTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSR 1777
Query: 476 PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRC 533
C N C N G Y C+C+ G+ P CV +EC E C+ C +T GS+ C
Sbjct: 1778 ESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGQNECREIPNVCSHGDCMDTEGSYMC 1837
Query: 534 TCPYGYAVAADGVHCRDIDECVQEPRVCPH-ACENVVGSYICKCPEGYRRTSAPQDSENA 592
C G+ +AD C DIDEC ++P C + C+N++GSY C C G+ T
Sbjct: 1838 LCHRGFQASADQTLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGFVVT-----HNGD 1890
Query: 593 CEDINECEE-QEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGR 651
C D +EC +C G C+NT GSF C C GFE + DG +C+D T C ++G
Sbjct: 1891 CVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVD--TNECLS--LAGT 1946
Query: 652 CEP 654
C P
Sbjct: 1947 CLP 1949
Score = 341 bits (837), Expect = 9e-93
Identities = 208/655 (31%), Positives = 294/655 (44%), Gaps = 59/655 (9%)
Query: 9 SCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPI 68
SC+ +GV T+ CCCS+G AWG PCE CP + + LC G N +T + I
Sbjct: 1512 SCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDI 1571
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC +P LC+ G C +T FQC C GY + +C D+DECS C G C N
Sbjct: 1572 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGIC-GPGTCYN 1630
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTI--GSYRCECKPGYTLRE 186
G + C CP Y + C D+ + R +G C+N + R C Y + +
Sbjct: 1631 TLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHY-NGTCQNELAFNVTRKMCCCSYNIGQ 1689
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
R + C P C N +L G +D++EC E +C NG
Sbjct: 1690 AWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTG-------KPLDIDECGEIPAICANG 1742
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
C N +GSFRCEC G+ + C DVDEC PC + N C N G Y C C
Sbjct: 1743 ICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQ--NADCINIPGSYRCKCTR 1800
Query: 307 GWKL-VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
G+KL G CV ++EC+E+P VC+ G+C + G Y+C C G++ +C+D
Sbjct: 1801 GYKLSPGGACVGQNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMD------ 1854
Query: 366 YDEWEAGRCHRARPLQ-LARPECCCSEG----------------AAWGRYCERCPAPDSA 408
DE + C + C C G G+ C ++A
Sbjct: 1855 IDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTA 1914
Query: 409 -EFMRICQGGM---GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
F +CQ G D +EC C+ G C N +GSFRC CP G+ + D
Sbjct: 1915 GSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSD-- 1972
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
C+D DEC+ +P +C GTC+N+ G ++C C PGF + C + R S C
Sbjct: 1973 HCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG-----HRCFDTRQSF---C 2024
Query: 525 HNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEP-RVCPHACENVVGSYICKCPEGYRR 582
+ +C+ P + C + E +P +CP + ++ CP G+
Sbjct: 2025 FTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCP---QEGSAAFQELCPFGHGA 2081
Query: 583 TSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
P DS ED+NEC E +C+ GVC+NTDGSF C+C G+ G +C+D
Sbjct: 2082 VPGPDDSR---EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVD 2133
Score = 336 bits (827), Expect = 1e-91
Identities = 216/646 (33%), Positives = 295/646 (45%), Gaps = 65/646 (10%)
Query: 23 CCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGT 82
CC ++G AWG+PCE C PA G VT + ++EC+ P +C G
Sbjct: 841 CCATLGAAWGSPCERCEI--DPACARGFARMTG-----VTCDD--VNECESFPGVCPNGR 891
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDV--DEC--SWGRPPCRGMAQCVNLPGAFE---C 135
C +T F+C C G D + LC DV + C W C V LPG + C
Sbjct: 892 CVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECG-----VTLPGKYRMDVC 946
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDEC 195
C G + C D + +C G +G + G +DV+EC
Sbjct: 947 CCSIGAVWGVECEACPDPESLEFASLCPRG-----LGFASRDFLSGRPFY----KDVNEC 997
Query: 196 SRPRPVCRNGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRNGRCRNTVGS 254
+C +GTC N G++ C C GF +C D++ECR +C G C NT GS
Sbjct: 998 KVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGS 1057
Query: 255 FRCECAPGYTLTAD-GRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV-- 311
F CEC PGY +NC DVDEC P C R G +CTNT+G Y+C C G +L
Sbjct: 1058 FECECFPGYESGFMLMKNCMDVDECARDPLLC-RGG--TCTNTDGSYKCQCPPGHELTAK 1114
Query: 312 GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK--------- 362
G C D DEC +C G+C N G + C C AG++ CVD +
Sbjct: 1115 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCD 1174
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCS---EGAAWGRYCERCPAPDSAEFMR-ICQGG- 417
C + + RC + L C+ E R C++ + R +C G
Sbjct: 1175 VHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGF 1234
Query: 418 MGRPNLTQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
M P++ D+DEC + P +C+ G C NT GSF C C GY++ C D DEC +
Sbjct: 1235 MATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVG 1294
Query: 476 PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFR 532
C + +C N G + C+C PG+ G C D+DEC C+ R C N GS+R
Sbjct: 1295 GHNCDSHASCLNIPGSFSCRCLPGWV-GDGFECHDLDECISQEHRCSPRGDCLNVPGSYR 1353
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSEN 591
CTC G+A DG C D DEC + +C + C N G Y C+C G+ P +
Sbjct: 1354 CTCRQGFA--GDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFD----PTEDHR 1407
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
AC+D++EC Q +LC+ G C N G F C C+ G+E G +C D
Sbjct: 1408 ACQDVDEC-AQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTD 1452
Score = 328 bits (807), Expect = 4e-89
Identities = 238/714 (33%), Positives = 308/714 (43%), Gaps = 111/714 (15%)
Query: 21 YLCCCSVGHAWGAPCEACPPRGSPAHTAL------CGEKPGEYINPV---------TNET 65
Y C C++G+ GA + C A +L C PG Y T
Sbjct: 712 YRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEIC 771
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS-WGR---PPCR 121
K +DEC P C G C + + C C G D + C D + + W + C
Sbjct: 772 KDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE 829
Query: 122 GMAQ--------CVNLPGAF-----ECR----CPPGYRLTPSLDECEDVDECGD-QRICD 163
Q C L A+ C C G+ + C+DV+EC +C
Sbjct: 830 VNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVT-CDDVNECESFPGVCP 888
Query: 164 HGDCRNTIGSYRCECKPGYTLREN--VCRDV-----------DECSRPRP--------VC 202
+G C NT GS+RCEC G L + +C DV DEC P C
Sbjct: 889 NGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCC 948
Query: 203 RNGT-----CENLPG------AYLCHCDDGFKA----GPNNDCVDVNECREGGMVCRNGR 247
G CE P A LC GF + DVNEC+ +C +G
Sbjct: 949 SIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT 1008
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
CRNTVGSF C CA G+ L A RNC D+DEC P CG+ +C NT G +EC C G
Sbjct: 1009 CRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG---TCVNTPGSFECECFPG 1065
Query: 308 WK---LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKE 363
++ ++ + C+D DEC P +C GG C N +G Y C+CP G C D +
Sbjct: 1066 YESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECS 1125
Query: 364 L---------CYDEWEAGRC--HRARPLQLARPECC-CSEGAAWGRYCE-RCPAPDSAEF 410
L C + A +C H R C +E C+ C + +
Sbjct: 1126 LSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYR 1185
Query: 411 MRICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
QG P+ D+DEC P VC G C N G RC C DG++ PD +CVD
Sbjct: 1186 CSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVD 1245
Query: 469 ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFR--CH 525
DEC L+P IC +G C NT+G + C C G+ T C DVDEC G +C C
Sbjct: 1246 VDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCL 1305
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECV-QEPRVCPHA-CENVVGSYICKCPEGYRRT 583
N GSF C C G+ DG C D+DEC+ QE R P C NV GSY C C +G+
Sbjct: 1306 NIPGSFSCRCLPGWV--GDGFECHDLDECISQEHRCSPRGDCLNVPGSYRCTCRQGFAGD 1363
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
CED +EC E DLC G C+N G + C+C+ GF+P+ED C D
Sbjct: 1364 GF------FCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1411
Score = 290 bits (711), Expect = 2e-77
Identities = 192/556 (34%), Positives = 250/556 (44%), Gaps = 83/556 (14%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC + C GTC + GF+C C G+E C D+DECS C +C N
Sbjct: 2135 DECSV-GHPCGQGTCTNVIGGFECACADGFE-PGLMMTCEDIDECSLNPLLCA--FRCHN 2190
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICD-HG-DCRNTIGSYRCECKPGYTLR 185
G++ C CP GY L C DVDEC D Q+ C G +C+N IG++ C C PG
Sbjct: 2191 TEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPL 2250
Query: 186 ENV---CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF------------KAGP---- 226
C D +EC +C NG C N G++ C CD+GF + GP
Sbjct: 2251 PGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAE 2310
Query: 227 -----------NNDCVDVNECREGGMVCRNGRCRNT----VGSFRCECAPGYTLTADGRN 271
+++ V EC GG RC ++R C G TA+GR
Sbjct: 2311 VLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGR- 2369
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK--LVGRRCVDRDECKELPYVCA 329
DVDEC L H C C N+ G + C C AG+ C+D DEC ++P C
Sbjct: 2370 --DVDECRMLAHLCAHG---ECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCT 2424
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C+N G ++C CP G+ ++ C D DE + R H + L C
Sbjct: 2425 F-LCKNTKGSFLCSCPRGYLLEEDGRTCKD------LDECTS-RQHNCQFL------CVN 2470
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGS 448
+ GA + RCP P + + C D DEC +P C G C NT GS
Sbjct: 2471 TVGA----FTCRCP-PGFTQHHQACF----------DNDECSAQPGPCGAHGHCHNTPGS 2515
Query: 449 FRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-C 507
FRCEC G+ L G C D +EC P C +G C N GGY C C GFTQ C
Sbjct: 2516 FRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQC 2573
Query: 508 VDVDECAEGRASC-TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
VD +ECA +C + C NT G FRC CP G+ C+D+DEC C ++C
Sbjct: 2574 VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYSCA 2633
Query: 567 NVVGSYICKCPEGYRR 582
N G ++C CP+GY R
Sbjct: 2634 NTPGGFLCGCPQGYFR 2649
Score = 290 bits (711), Expect = 2e-77
Identities = 195/525 (37%), Positives = 244/525 (46%), Gaps = 87/525 (16%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC--RGMAQ 125
IDEC + P LC CH+T + C C GY +CRDVDEC+ G+ C RGM +
Sbjct: 2174 IDECSLNPLLCA-FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGM-E 2231
Query: 126 CVNLPGAFECRCPPGYRLTPSLDE-CEDVDECGDQR-ICDHGDCRNTIGSYRCECKPGY- 182
C NL G F C CPPG R P E C D +EC Q +C +G C NT GS+RC+C G+
Sbjct: 2232 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2291
Query: 183 ---TLRE---------------NVCRDVDECS----RPRPVCRNGT-----CE--NLPG- 212
TL E +CR + S R C G CE LPG
Sbjct: 2292 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGT 2351
Query: 213 -AYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRN 271
AY C G +G + DV+ECR +C +G C N++GSFRC C GYT A
Sbjct: 2352 SAYRKLCPHG--SGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATT 2409
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCA 329
C D+DEC ++P PC C NT G + CSC G+ L GR C D DEC + C
Sbjct: 2410 CLDMDECSQVPKPC----TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQ 2465
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C N G + C CP G+ + + C+D E A+P C
Sbjct: 2466 F-LCVNTVGAFTCRCPPGFT----------QHHQACFDNDECS----------AQPGPCG 2504
Query: 390 SEGAAWGRYCERCPAPDSAEFMR---ICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTD 446
+ G +C P E + + G G +D++EC P C G C N
Sbjct: 2505 AHG-----HCHNTPGSFRCECHQGFTLVSSGHG----CEDVNECD-GPHRCQHG-CQNQL 2553
Query: 447 GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT 506
G +RC CP G+ CVD +ECAL P CG+ +C NT GG+ C C GF DQ
Sbjct: 2554 GGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDF--DQA 2611
Query: 507 ---CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC 548
C DVDECA R C++ C NT G F C CP GY A G HC
Sbjct: 2612 LGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG-HC 2655
Score = 287 bits (704), Expect = 1e-76
Identities = 241/778 (30%), Positives = 309/778 (39%), Gaps = 109/778 (14%)
Query: 122 GMAQCVNLPGAFECR--CPPGYRLTPSLDECED---VDECGDQRICDHG-DCRN--TIGS 173
G +QCV +P CR C G+ P+L C D CG R C N T
Sbjct: 84 GRSQCV-VP---ICRRACGEGFCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMNGGTCRG 139
Query: 174 YRCECKPGYTLRENVCRDVDECSRPRPVCRNG-------TCENLPGAYLCHCDDGFKAGP 226
C C+ GYT VC C R C NG C + G C+ ++ GP
Sbjct: 140 ASCLCQKGYT--GTVCGQ-PICDRG---CHNGGRCIGPNRCACVYGFMGPQCERDYRTGP 193
Query: 227 NNDCVDVNECREG--GMVCRNGRCRNTVG---SFRCECAP--------GYTLTADGRNCR 273
V C+ G+VC C TVG CE P G+ C+
Sbjct: 194 CFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQ 253
Query: 274 DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPY-VCAGGE 332
DVDEC +P C G SC N G + C C G +L D + V GG
Sbjct: 254 DVDECQAVPGLC--QGG-SCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGR 310
Query: 333 CRNFNGGYV----CECPAG--WRFDKTAAVCV----DERKELCYDEWEAGRCHRAR-PLQ 381
C G+ C C G W +C +E ++LC H P
Sbjct: 311 CAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGL 370
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
L R + +G L Q +D CR ++C+ GR
Sbjct: 371 LGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGR 430
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
C+ T S+RCEC GY G C+D DEC P C +G C N G Y C+C PGF
Sbjct: 431 CLPTPSSYRCECNVGYTQDVRG-ECIDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQA 487
Query: 502 GPD-QTCVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPR 559
P Q CVDVDEC C RC NT GSF+C C G+ ++ DG +C D +EC
Sbjct: 488 TPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 547
Query: 560 VCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFL 619
C N GS+ C C G+ AP + C DI+EC + +C G C NT+GSF
Sbjct: 548 CVNGVCLNEDGSFSCLCKPGF--LLAP--GGHYCMDIDEC-QTPGICVNGHCTNTEGSFR 602
Query: 620 CDCDAGFEPSEDGTDCIDRRT-GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXG 678
C C G DG C+D TCY ++ G C G
Sbjct: 603 CQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSC--------------------ARPFPG 642
Query: 679 HVTKAQCCC-TLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXX 737
VTK++CCC +G C+LCPA S LC++
Sbjct: 643 TVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSS----------------GLGITTD 686
Query: 738 XXXXLDVFADVDECAAIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ 793
+ D + CA G+C G +RCVC GY +G+ C DVDECA+ CD
Sbjct: 687 GRDINECALDPEVCA--NGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDN 744
Query: 794 -LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
C N+ GSY C C G+ +D C+DVDEC + +C N GSY C C G
Sbjct: 745 GWCQNSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPG 801
Score = 263 bits (644), Expect = 2e-69
Identities = 204/618 (33%), Positives = 258/618 (41%), Gaps = 70/618 (11%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGA-PC-EACPPRGSPAHTALCGEK-------PGEYINP 60
CAG + T+ CCC G W A P E CPPRGS LC ++ PG +
Sbjct: 311 CAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGL 370
Query: 61 VTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+ + + + P P H + G + T+ L + +D C C
Sbjct: 371 LGFGSNGMGP-PLGPARLNP---HGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLC 426
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
+C+ P ++ C C GY EC DVDEC C HGDC N G+Y C C P
Sbjct: 427 LN-GRCLPTPSSYRCECNVGY-TQDVRGECIDVDECTSSP-CHHGDCVNIPGTYHCRCYP 483
Query: 181 GY--TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECR 237
G+ T C DVDEC +C G C N G++ C C+ GF+ P+ +CVD NEC
Sbjct: 484 GFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECA 543
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTN 297
M C NG C N GSF C C PG+ L G C D+DEC + P C N CTNT
Sbjct: 544 TSTM-CVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDEC-QTPGIC---VNGHCTNTE 598
Query: 298 GGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGEC-RNFNGGYV---CECP-AGWRF 350
G + C C G + GR CVD G C R F G C C F
Sbjct: 599 GSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGF 658
Query: 351 DKTAAVC----VDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPD 406
+ +C E + LC R PE C + R RC
Sbjct: 659 GEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNL 718
Query: 407 SAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
E G G+ D+DEC + +C G C N+ GS+ C CP G+ D C
Sbjct: 719 GYE-----AGASGKD--CTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEIC 771
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDE--C----AEGR-- 517
D DEC P C +G C N G Y C+C PG P T C+D + C E R
Sbjct: 772 KDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE 829
Query: 518 -----ASCTFRCHNTAGSF------RC----TCPYGYAVAADGVHCRDIDECVQEPRVCP 562
AS C T G+ RC C G+A GV C D++EC P VCP
Sbjct: 830 VNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFA-RMTGVTCDDVNECESFPGVCP 888
Query: 563 HA-CENVVGSYICKCPEG 579
+ C N GS+ C+CPEG
Sbjct: 889 NGRCVNTAGSFRCECPEG 906
Score = 258 bits (633), Expect = 5e-68
Identities = 221/687 (32%), Positives = 281/687 (40%), Gaps = 129/687 (18%)
Query: 40 PRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYE 99
P GS A + PG + ID C LC G C TP+ ++C C+ GY
Sbjct: 389 PHGSDAR-GIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYT 447
Query: 100 HDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GD 158
D C DVDEC+ PC CVN+PG + CRC PG++ TP+ C DVDEC
Sbjct: 448 QDVRGE-CIDVDECT--SSPCH-HGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVS 503
Query: 159 QRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLC 216
+C G C NT GS++C C G+ L + C D +EC+ +C NG C N G++ C
Sbjct: 504 GGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECA-TSTMCVNGVCLNEDGSFSC 562
Query: 217 HCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV 275
C GF P C+D++EC+ G +C NG C NT GSFRC+C G + DGR C D
Sbjct: 563 LCKPGFLLAPGGHYCMDIDECQTPG-ICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDT 621
Query: 276 ---DEC--------DELPHP---------CGRD----GNPS--CTNTNGG-YECSCGAGW 308
C P P C G P C N ++ C +G
Sbjct: 622 HVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGL 681
Query: 309 KLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCY 366
+ GR D +EC P VCA G C N G Y C C G+ + C D
Sbjct: 682 GITTDGR---DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTD------V 732
Query: 367 DEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM---GRPNL 423
DE C A C G +C+ P S C G +
Sbjct: 733 DE-----C--------ALNSLLCDNG-----WCQNSPGSYSCS----CPPGFHFWQDTEI 770
Query: 424 TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA---------DECAL 474
+D+DEC P CV G C N GS+ C+C G L P G C+D+ E
Sbjct: 771 CKDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRC 828
Query: 475 DPRICG---NGTCSNTRG---GYECQ-------CSPGFTQGPDQTCVDVDECAEGRASC- 520
+ + G C T G G C+ C+ GF + TC DV+EC C
Sbjct: 829 EVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCP 888
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRDI-----------DEC-VQEP-----RVCPH 563
RC NTAGSFRC CP G + A G C D+ DEC V P VC
Sbjct: 889 NGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCC 948
Query: 564 ACENVVG------------SYICKCPEGYRRTSAP-QDSENACEDINECEEQEDLCSGGV 610
+ V G + CP G S +D+NEC+ LC+ G
Sbjct: 949 SIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT 1008
Query: 611 CINTDGSFLCDCDAGFEPSEDGTDCID 637
C NT GSF C C GF +C D
Sbjct: 1009 CRNTVGSFHCACAGGFALDAQERNCTD 1035
Score = 237 bits (580), Expect = 1e-61
Identities = 170/513 (33%), Positives = 219/513 (42%), Gaps = 93/513 (18%)
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGR 287
N +D+ CR +C NGRC T S+RCEC GYT G C DVDEC P G
Sbjct: 413 NQTIDI--CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDECTSSPCHHG- 468
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECP 345
C N G Y C C G++ R CVD DEC +C G C N G + C C
Sbjct: 469 ----DCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCN 524
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
AG+ CVD + C + + C +E ++ C+ P
Sbjct: 525 AGFELSPDGKNCVDHNE-----------CATST---MCVNGVCLNEDGSFSCLCK--PG- 567
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
F+ + GG + D+DEC+ P +CV G C NT+GSFRC+C G + DG
Sbjct: 568 ----FL-LAPGG----HYCMDIDECQT-PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRV 617
Query: 466 CVDA---DEC--ALDPRICGN---GT-------CSNTRGGY--ECQCSPGFTQGPDQTCV 508
CVD C A++ C GT C+N G+ CQ P Q
Sbjct: 618 CVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALC 677
Query: 509 -----------DVDECAEGRASCTFR-CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
D++ECA C C N GS+RC C GY A G C D+DEC
Sbjct: 678 SSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECAL 737
Query: 557 EPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTD 615
+C + C+N GSY C CP G+ QD+E C+D++EC C GVC N
Sbjct: 738 NSLLCDNGWCQNSPGSYSCSCPPGFHFW---QDTE-ICKDVDECLSSP--CVSGVCRNLA 791
Query: 616 GSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXX 675
GS+ C C G GT C+D GTC+ + RCE
Sbjct: 792 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE--------------------VN 831
Query: 676 XXGHVTKAQCCCTLGAAWGSECELCPAPGSPAR 708
G +++CC TLGAAWGS CE C + AR
Sbjct: 832 LQGASLRSECCATLGAAWGSPCERCEIDPACAR 864
Score = 212 bits (517), Expect = 5e-54
Identities = 157/523 (30%), Positives = 203/523 (38%), Gaps = 74/523 (14%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAW---GAPC----------EACPPRGSPAH----TALCGE 52
CA + YLC C G+ GA C + C RG T C
Sbjct: 2184 CAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVC 2243
Query: 53 KPGEYINPVTNETKPID-ECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVD 111
PG P + E D EC P LC G C +T F+C CD G++ T C D+
Sbjct: 2244 PPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIR 2303
Query: 112 E----CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDC 167
+ + CR ++ EC C G P + C +++C HG
Sbjct: 2304 QGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGS- 2362
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN 227
GYT RDVDEC +C +G C N G++ CHC G+
Sbjct: 2363 -------------GYTAEG---RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDAT 2406
Query: 228 -NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C+D++EC + C C+NT GSF C C GY L DGR C+D+DEC H C
Sbjct: 2407 ATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNC- 2464
Query: 287 RDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVC-AGGECRNFNGGYVCECP 345
C NT G + C C G+ + C D DEC P C A G C N G + CEC
Sbjct: 2465 ---QFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECH 2521
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
G+ + C D + C RC QL C C +G +C
Sbjct: 2522 QGFTLVSSGHGCEDVNE--CDGPH---RCQHGCQNQLGGYRCSCPQGFTQHSQWAQCV-- 2574
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
D +EC + P C C NT G FRC CP G+
Sbjct: 2575 --------------------DENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGG 2614
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV 508
C D DECA C +C+NT GG+ C C G+ + CV
Sbjct: 2615 CQDVDECAGRRGPCSY-SCANTPGGFLCGCPQGYFRAGQGHCV 2656
Score = 180 bits (438), Expect = 2e-44
Identities = 99/242 (40%), Positives = 122/242 (50%), Gaps = 22/242 (9%)
Query: 414 CQGGMGRPNLTQ----DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
CQ G P+ T D+DEC P C C NT GSF C CP GY+L DG +C D
Sbjct: 2397 CQAGY-TPDATATTCLDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDL 2454
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNT 527
DEC C C NT G + C+C PGFTQ Q C D DEC+ C CHNT
Sbjct: 2455 DECTSRQHNC-QFLCVNTVGAFTCRCPPGFTQH-HQACFDNDECSAQPGPCGAHGHCHNT 2512
Query: 528 AGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQ 587
GSFRC C G+ + + G C D++EC P C H C+N +G Y C CP+G+ + S Q
Sbjct: 2513 PGSFRCECHQGFTLVSSGHGCEDVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHS--Q 2569
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE------PSEDGTDCIDRRTG 641
++ C D NEC C C NT G F C C +GF+ +D +C RR G
Sbjct: 2570 WAQ--CVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRR-G 2626
Query: 642 TC 643
C
Sbjct: 2627 PC 2628
Score = 98.7 bits (235), Expect = 8e-20
Identities = 116/418 (27%), Positives = 158/418 (37%), Gaps = 56/418 (13%)
Query: 250 NTVGS-FRCECAPGYTLTADGRNCRDVDECDELPHPCGRD--GNPS-CTNTNGGYECSCG 305
N GS F C PG+ T GR+ V C CG P+ CT +G SCG
Sbjct: 65 NVCGSRFHAYCCPGWR-TFPGRSQCVVPICRRA---CGEGFCSQPNLCTCADGTLAPSCG 120
Query: 306 AG-WKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCE--CPAGWR-FDKTAAVCV--- 358
C++ C+ +C G G +C+ C G R CV
Sbjct: 121 VSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCACVYGF 180
Query: 359 -------DERKELCYDEWEAGRC-HRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
D R C+ + C H+ L + CC + G AWG CE CPA
Sbjct: 181 MGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHP-- 238
Query: 411 MRICQGGMGRPNL----TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
C+ G PN+ QD+DEC+ P +C GG CVN GSF C CP G+ L+ +C
Sbjct: 239 ---CRRGF-IPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAAC 294
Query: 467 VDADECALDPRICGNGTCSNTRGGY----ECQCSPG--FTQGPDQTCVDVDECAEGRASC 520
D A + G G C+ G+ +C C G + GP E + C
Sbjct: 295 EDYRAGACFSVLFG-GRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLC 353
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPE-G 579
R G P G G + + R+ PH GS P G
Sbjct: 354 AQRLPLLPGH-----P-GLFPGLLGFGSNGMGPPLGPARLNPH------GSDARGIPSLG 401
Query: 580 YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
++ + N DI C +LC G C+ T S+ C+C+ G+ G +CID
Sbjct: 402 PGNSNIGTATLNQTIDI--CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRG-ECID 456
Score = 98.3 bits (234), Expect = 1e-19
Identities = 46/113 (40%), Positives = 57/113 (50%), Gaps = 9/113 (7%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL--CHNT 798
D+DEC + C G F C C PG+ + C D DEC+ +P PC CHNT
Sbjct: 2453 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNT 2512
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
GS+ C C G+ L G C DV+EC+ H CQ C N G Y CSC G+
Sbjct: 2513 PGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHGCQNQLGGYRCSCPQGF 2564
Score = 97.9 bits (233), Expect = 1e-19
Identities = 51/124 (41%), Positives = 61/124 (49%), Gaps = 11/124 (8%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHN 797
D DECA LC APG +RC C G+ P + C DVDECA C N
Sbjct: 1369 DRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCEN 1428
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRG 855
G + C+C GYELD G NC D++EC + +C NT GSY CSC +E G
Sbjct: 1429 LPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1488
Query: 856 DACV 859
CV
Sbjct: 1489 VGCV 1492
Score = 89.0 bits (211), Expect = 6e-17
Identities = 39/103 (37%), Positives = 54/103 (52%), Gaps = 4/103 (3%)
Query: 761 GRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDEDGA 817
G +RC C G+ + C D +ECA+ PP C C NT G + C+C +G++ D+
Sbjct: 2554 GGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALG 2613
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
C+DVDEC C C+NT G + C C GY + G CV
Sbjct: 2614 GCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCV 2656
Score = 83.8 bits (198), Expect = 2e-15
Identities = 49/125 (39%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQ--LC 795
DVDEC P +C G F C C GY R C+DVDEC V CD C
Sbjct: 1245 DVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASC 1304
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEK 853
N GS+ C C G+ DG C D+DEC H C C N GSY C+C G+
Sbjct: 1305 LNIPGSFSCRCLPGWV--GDGFECHDLDECISQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1362
Query: 854 RGDAC 858
G C
Sbjct: 1363 DGFFC 1367
Score = 80.6 bits (190), Expect = 2e-14
Identities = 44/117 (37%), Positives = 53/117 (45%), Gaps = 12/117 (10%)
Query: 747 DVDECAAIPGLCA--------PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCH 796
D DEC+A PG C PG FRC C G+ +G C DV+EC P C C
Sbjct: 2492 DNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHGCQ 2550
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYE 852
N G Y C C G+ A C D +EC TC C NT G + C C G++
Sbjct: 2551 NQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFD 2607
Score = 73.3 bits (172), Expect = 3e-12
Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 7/95 (7%)
Query: 15 GVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIM 74
G+ TK LCC +VG AWG PCE CP + P + G N T + +DEC +
Sbjct: 209 GLVCTKALCCATVGRAWGLPCELCPAQPHPC-------RRGFIPNIHTGACQDVDECQAV 261
Query: 75 PQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
P LC+ G+C + F C C G+ ++S C D
Sbjct: 262 PGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 296
Score = 70.9 bits (166), Expect = 2e-11
Identities = 45/120 (37%), Positives = 58/120 (48%), Gaps = 12/120 (10%)
Query: 751 CAAIPGLCAPGRFRCVCG---PGYRP---AGEVCADVDECAVRPPPC-DQLCHNTDGSYD 803
C A P +P ++ +CG PG+ G+ D+DEC P C + +C N GS+
Sbjct: 1695 CEACPTPISPD-YQILCGNQAPGFLTDIHTGKPL-DIDECGEIPAICANGICINQIGSFR 1752
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE-KRGDACVG 860
C C G+ + C DVDEC CQQ C N GSY C C GY+ G ACVG
Sbjct: 1753 CECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVG 1812
Score = 50.4 bits (115), Expect = 3e-05
Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 32/149 (21%)
Query: 743 DVFADVDECAAIP---GLCA--PGRFRCVCGPGYR--PAGEVCADVDE--C--AVRPPPC 791
++ DVDEC + P G+C G + C CGPG R P+G C D + C ++ C
Sbjct: 769 EICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRC 828
Query: 792 DQLCHNTDGSYDCLCRTGY---------ELDE---------DGANCRDVDECERDTHTCQ 833
+ +C G E+D G C DV+ECE C
Sbjct: 829 EVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCP 888
Query: 834 Q-ICSNTEGSYECSCEDG--YEKRGDACV 859
C NT GS+ C C +G + G CV
Sbjct: 889 NGRCVNTAGSFRCECPEGLMLDASGRLCV 917
Score = 48.0 bits (109), Expect = 1e-04
Identities = 57/195 (29%), Positives = 74/195 (37%), Gaps = 34/195 (17%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
GTC G C C GY T +C C G C +C+ G C C G
Sbjct: 135 GTCR----GASCLCQKGY----TGTVCGQ-PICDRG---CHNGGRCI---GPNRCACVYG 179
Query: 141 YRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRP 200
+ + P +CE D R G C +G C+ + L VC C+
Sbjct: 180 F-MGP---QCER-----DYRT---GPCFGQVGPEGCQ----HQLTGLVCTKALCCATVGR 223
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCEC 259
CE P A C GF + C DV+EC+ +C+ G C N VGSF C C
Sbjct: 224 AW-GLPCELCP-AQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRC 281
Query: 260 APGYTLTADGRNCRD 274
G+ L+ C D
Sbjct: 282 PVGHRLSDSSAACED 296
Score = 38.7 bits (86), Expect = 0.087
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGY 851
CR G+ + C+DVDEC+ CQ C N GS+ C C G+
Sbjct: 239 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGH 285
>AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 3 protein.
Length = 2809
Score = 728 bits (1799), Expect = 0.0
Identities = 355/869 (40%), Positives = 460/869 (52%), Gaps = 64/869 (7%)
Query: 9 SCAGAVGVPQTKYLCCCS--VGHAWGAPCEACPPRGSPAHTALCGEK-PGEYINPVTNET 65
+C + T+ +CCCS +G AW PCEACP SP + LCG + PG + T +
Sbjct: 1660 TCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKP 1719
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ 125
IDEC +P +C G C + F+C C G+ +++ C DVDEC PC+ A
Sbjct: 1720 LDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCECKPGY-- 182
C+N+PG++ C+C GY+L+P C +EC + +C HGDC +T GSY C C G+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPG-GACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQA 1838
Query: 183 TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE-GGM 241
+ + +C D+DEC R +P C NGTC+N+ G+Y C C GF N DCVD +EC G
Sbjct: 1839 SADQTLCMDIDECDR-QP-CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 242 VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
VCR G C NT GSF C C G+ LTADG+NC D +EC L C G +C N G +
Sbjct: 1897 VCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTC-LPG--TCQNLEGSFR 1953
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER 361
C C G+++ C+D DEC E P +C G C N G + C CP G+ C D R
Sbjct: 1954 CICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTR 2013
Query: 362 KELCYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMRICQGGMG 419
+ C+ +EAG+C + + CCCS+ G WG CE CP SA F +C G G
Sbjct: 2014 QSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHG 2073
Query: 420 R----PNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
+ +D++EC P VC G CVNTDGSFRCECP GY L G++CVD DEC++
Sbjct: 2074 AVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG 2133
Query: 476 PRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
CG GTC+N GG+EC C+ GF G TC D+DEC+ C FRCHNT GS+ CTC
Sbjct: 2134 -HPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTC 2192
Query: 536 PYGYAVAADGVHCRDIDECVQEPRVCPHA----CENVVGSYICKCPEGYRRTSAPQDSEN 591
P GY + DG CRD+DEC + C HA C+N++G++ C CP G R P E
Sbjct: 2193 PAGYTLREDGAMCRDVDECADGQQDC-HARGMECKNLIGTFACVCPPGMR--PLPGSGE- 2248
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGR 651
C D NEC Q DLC G C+NT GSF CDCD GF+PS T+C D R G C+ ++
Sbjct: 2249 GCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTM 2308
Query: 652 CEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDL 711
C VT+A+CCC G WG CELCP PG+ A L
Sbjct: 2309 CR------------------SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKL 2350
Query: 712 CTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCAPGRFRCVCGPGY 771
C + A + CA + + G FRC C GY
Sbjct: 2351 CP--------------HGSGYTAEGRDVDECRMLAHL--CAHGECINSLGSFRCHCQAGY 2394
Query: 772 RP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDT 829
P C D+DEC+ P PC LC NT GS+ C C GY L+EDG C+D+DEC
Sbjct: 2395 TPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQ 2454
Query: 830 HTCQQICSNTEGSYECSCEDGYEKRGDAC 858
H CQ +C NT G++ C C G+ + AC
Sbjct: 2455 HNCQFLCVNTVGAFTCRCPPGFTQHHQAC 2483
Score = 458 bits (1129), Expect = e-128
Identities = 268/748 (35%), Positives = 343/748 (45%), Gaps = 83/748 (11%)
Query: 151 EDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTLR-ENVCRDVDECSRPRPVCRNGTCE 208
+ +D C +C +G C T SYRCEC GYT C DVDEC+ C +G C
Sbjct: 407 QTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSP--CHHGDCV 464
Query: 209 NLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTA 267
N+PG Y C C GF+A P CVDV+EC G +C GRC NT GSF+C C G+ L+
Sbjct: 465 NIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSP 524
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELP 325
DG+NC D +EC C N C N +G + C C G+ L G C+D DEC + P
Sbjct: 525 DGKNCVDHNEC-ATSTMCV---NGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDEC-QTP 579
Query: 326 YVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER-KELCYDEWEAGRCHRARPLQLAR 384
+C G C N G + C+C G VCVD + CY E G C R P + +
Sbjct: 580 GICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTK 639
Query: 385 PECCCSE-GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCV 443
ECCC+ +G C+ CPA +SAEF +C G+G +D++EC + P+VC G C
Sbjct: 640 SECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCE 699
Query: 444 NTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
N GS+RC C GY G C D DECAL+ +C NG C N+ G Y C C PGF
Sbjct: 700 NLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQ 759
Query: 504 D-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP 562
D + C DVDEC + C N AGS+ C C G + G C D + ++
Sbjct: 760 DTEICKDVDECLSS-PCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQE 818
Query: 563 HACE-NVVGSYI---CKCPEGYRRTSAPQDSE--------------NACEDINECEEQED 604
CE N+ G+ + C G S + E C+D+NECE
Sbjct: 819 SRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPG 878
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXX 664
+C G C+NT GSF C+C G G C+D R C+ C
Sbjct: 879 VCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDEC------------ 926
Query: 665 XXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXX 724
G CCC++GA WG ECE CP P S LC
Sbjct: 927 --------GVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCP----------- 967
Query: 725 XXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLC-------APGRFRCVCGPGYRPAGEV 777
+ DV+EC PGLC G F C C G+ +
Sbjct: 968 ----RGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQE 1023
Query: 778 --CADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD-EDGANCRDVDECERDTHTCQ 833
C D+DEC + P C Q C NT GS++C C GYE NC DVDEC RD C+
Sbjct: 1024 RNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCR 1083
Query: 834 -QICSNTEGSYECSCEDGYE--KRGDAC 858
C+NT+GSY+C C G+E +G AC
Sbjct: 1084 GGTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Score = 442 bits (1090), Expect = e-123
Identities = 286/830 (34%), Positives = 359/830 (43%), Gaps = 101/830 (12%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+DEC P LC+ GTC +T ++C C G+E C D+DECS C QCV
Sbjct: 1072 VDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH-GQCV 1130
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
N+ GAF+C C G++ TP C D++EC Q C NT GSYRC C GY+L +
Sbjct: 1131 NVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPD 1190
Query: 188 --VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCR 244
C DVDEC VC G C N+PG + C C DGF A P+ CVDV+EC +C
Sbjct: 1191 GRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICL 1250
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
+G C NT GSF C C GY + C DVDEC+ H C D + SC N G + C C
Sbjct: 1251 HGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNC--DSHASCLNIPGSFSCRC 1308
Query: 305 GAGWKLVGRRCVDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
GW G C D DEC + C+ G+C N G Y C C G+ D DE E
Sbjct: 1309 LPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAE 1368
Query: 364 --------LCYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMR- 412
C + RC C + A G C + R
Sbjct: 1369 NVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRC 1428
Query: 413 ICQGGM----GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
IC GG G N T D++EC P C+ G C+NT GS+ C CP + L P G+ CVD
Sbjct: 1429 ICNGGYELDRGGGNCT-DINEC-ADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVD 1486
Query: 469 --ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRA---SCTFR 523
A C L+ G+ G C G C C+ GRA C
Sbjct: 1487 TRAGNCFLETHDRGDS-------GISCSAEIGVGVTRASCC-----CSLGRAWGNPCELC 1534
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHC--RDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
+R CP G + + DIDEC + P +C C N GS+ C+CP GY
Sbjct: 1535 PMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGY 1594
Query: 581 RRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRT 640
+ + CEDI+EC +C G C NT G++ C C A + G +C+D R
Sbjct: 1595 HLS----EHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRK 1650
Query: 641 GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCT--LGAAWGSECE 698
C+R +G C+ E +VT+ CCC+ +G AW CE
Sbjct: 1651 SVCFRH-YNGTCQNELAF--------------------NVTRKMCCCSYNIGQAWNRPCE 1689
Query: 699 LCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLC 758
CP P SP LC N P D+DEC IP +C
Sbjct: 1690 ACPTPISPDYQILCG--NQAPGFLTDIHTGKP---------------LDIDECGEIPAIC 1732
Query: 759 AP-------GRFRCVCGPG--YRPAGEVCADVDECAVRPPPCDQL--CHNTDGSYDCLCR 807
A G FRC C G Y C DVDEC R PC Q C N GSY C C
Sbjct: 1733 ANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCT 1792
Query: 808 TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
GY+L GA C +EC + C C +TEGSY C C G++ D
Sbjct: 1793 RGYKLSPGGA-CVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASAD 1841
Score = 430 bits (1060), Expect = e-120
Identities = 232/592 (39%), Positives = 291/592 (49%), Gaps = 47/592 (7%)
Query: 1 MEWNEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
+ W+E++ C + +CCCS+G WG CEACP S +LC G
Sbjct: 919 LRWDEDE--CGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRD 976
Query: 61 VTNET---KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGR 117
+ K ++EC + P LC GTC +T F C C G+ D C D+DEC
Sbjct: 977 FLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISP 1036
Query: 118 PPCRGMAQCVNLPGAFECRCPPGYRLTPSL-DECEDVDECG-DQRICDHGDCRNTIGSYR 175
C G CVN PG+FEC C PGY L C DVDEC D +C G C NT GSY+
Sbjct: 1037 DLC-GQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYK 1095
Query: 176 CECKPGY--TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVD 232
C+C PG+ T + C D+DECS +C +G C N+ GA+ C C GF++ P+ CVD
Sbjct: 1096 CQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVD 1155
Query: 233 VNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
+NECR C + C NT GS+RC C GY+L DGR C DVDEC+E P C +
Sbjct: 1156 INECRVQNGGC-DVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQG---H 1211
Query: 293 CTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRF 350
CTN GG+ C C G+ R CVD DEC P++C G+C N G +VC C G+
Sbjct: 1212 CTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMV 1271
Query: 351 DKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
K A C D DE E G H C A+ C P S
Sbjct: 1272 RKGATGCSD------VDECEVGG-HN------------CDSHAS----CLNIPGSFSC-- 1306
Query: 411 MRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
R G +G DLDEC + C G C+N GS+RC C G+ A DG C D
Sbjct: 1307 -RCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCEDR 1363
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTA 528
DECA + +C NG C N GGY C+C GF D + C DVDECA+G C N
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLP 1423
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGY 580
G FRC C GY + G +C DI+EC C N GSY+C CP+ +
Sbjct: 1424 GMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDF 1475
Score = 409 bits (1007), Expect = e-113
Identities = 300/917 (32%), Positives = 373/917 (40%), Gaps = 98/917 (10%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPID 69
C VG Q C V +PC P T C PG P +D
Sbjct: 433 CECNVGYTQDVRGECIDVDECTSSPCHHGDCVNIPG-TYHCRCYPGFQATPTRQACVDVD 491
Query: 70 ECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
EC + LC G C +T FQC C+ G+E C D +EC+ G+ C+N
Sbjct: 492 ECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGV--CLNE 549
Query: 130 PGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN-- 187
G+F C C PG+ L P C D+DEC IC +G C NT GS+RC+C G + +
Sbjct: 550 DGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGR 609
Query: 188 VCRDVD------------ECSRPRP--VCRNGTCENLPG------AYLCHCDDG--FKA- 224
VC D C+RP P V ++ C P LC + F+A
Sbjct: 610 VCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQAL 669
Query: 225 -----GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECD 279
G D D+NEC VC NG C N GS+RC C GY A G++C DVDEC
Sbjct: 670 CSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECA 729
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFN 337
C N C N+ G Y CSC G+ C D DEC P C G CRN
Sbjct: 730 LNSLLCD---NGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLA 784
Query: 338 GGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGR 397
G Y C+C G R D + C+D K C+ + + RC R ECC + GAAWG
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGS 844
Query: 398 YCERCPAPDSAEFMRICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPD 455
CERC E C G R D++EC P VC GRCVNT GSFRCECP+
Sbjct: 845 PCERC------EIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPE 898
Query: 456 GYVLAPDGLSCVDA--DECAL--DPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDV 510
G +L G CVD + C L D CG R C CS G G + + C D
Sbjct: 899 GLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDV-CCCSIGAVWGVECEACPD- 956
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH-ACENVV 569
E E + C + F P+ +D++EC P +C H C N V
Sbjct: 957 PESLEFASLCPRGLGFASRDFLSGRPF----------YKDVNECKVFPGLCTHGTCRNTV 1006
Query: 570 GSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP- 628
GS+ C C G+ A E C DI+EC DLC G C+NT GSF C+C G+E
Sbjct: 1007 GSFHCACAGGF----ALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESG 1062
Query: 629 ----------SEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXG 678
E D + R GTC + S +C+ G
Sbjct: 1063 FMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDG 1122
Query: 679 HVTKAQCCCTLGAAWGS-ECELCPAPGSPARLDL--CTAVNLTPXXXXXXXXXXXXXXXX 735
QC +GA S P +D+ C N
Sbjct: 1123 LCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCG 1182
Query: 736 XXXXXXLD--VFADVDECAAIPGLC-------APGRFRCVCGPGY--RPAGEVCADVDEC 784
D ADVDEC P +C PG RC+C G+ P C DVDEC
Sbjct: 1183 QGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDEC 1242
Query: 785 AVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEG 841
+ P C C NT GS+ C C+ GY + + C DVDECE H C C N G
Sbjct: 1243 DLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPG 1302
Query: 842 SYECSCEDGYEKRGDAC 858
S+ C C G+ G C
Sbjct: 1303 SFSCRCLPGWVGDGFEC 1319
Score = 405 bits (996), Expect = e-112
Identities = 224/611 (36%), Positives = 293/611 (47%), Gaps = 53/611 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDE--------------- 112
IDEC P LC GTC ++P FQC C G+ + H C D +
Sbjct: 1970 IDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVP 2029
Query: 113 ---------CSWGRPPCRGMAQ-CVNLP----GAFECRCPPGYRLTPSLDEC-EDVDECG 157
C + P G C P AF+ CP G+ P D+ EDV+EC
Sbjct: 2030 KAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECA 2089
Query: 158 DQR-ICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAY 214
+ +C +G C NT GS+RCEC GY+L C D DECS P C GTC N+ G +
Sbjct: 2090 ENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP-CGQGTCTNVIGGF 2148
Query: 215 LCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRD 274
C C DGF+ G C D++EC ++C RC NT GS+ C C GYTL DG CRD
Sbjct: 2149 ECACADGFEPGLMMTCEDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Query: 275 VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV---GRRCVDRDECKELPYVCAGG 331
VDEC + C G C N G + C C G + + G C D +EC P +C G
Sbjct: 2208 VDECADGQQDCHARGM-ECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNG 2266
Query: 332 ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLA--RPECCC 389
C N G + C+C G++ T C D R+ C+ E C A R ECCC
Sbjct: 2267 RCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCC 2326
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
G WG CE CP P ++ + ++C G G +D+DECR+ +C G C+N+ GSF
Sbjct: 2327 GGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSF 2386
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCV 508
RC C GY +C+D DEC+ P+ C C NT+G + C C G+ D +TC
Sbjct: 2387 RCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCK 2445
Query: 509 DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC-PHA-CE 566
D+DEC + +C F C NT G+F C CP G+ C D DEC +P C H C
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQA--CFDNDECSAQPGPCGAHGHCH 2503
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
N GS+ C+C +G+ S S + CED+NEC+ C G C N G + C C GF
Sbjct: 2504 NTPGSFRCECHQGFTLVS----SGHGCEDVNECDGPH-RCQHG-CQNQLGGYRCSCPQGF 2557
Query: 627 EPSEDGTDCID 637
C+D
Sbjct: 2558 TQHSQWAQCVD 2568
Score = 395 bits (972), Expect = e-109
Identities = 287/876 (32%), Positives = 377/876 (43%), Gaps = 134/876 (15%)
Query: 21 YLCCCSVGHAW---GAPCEACPPRGSPAH--TALCGEKPGEYIN--PVTNETKP--IDEC 71
+ C C+ G+ G C P + +C PG Y+ P E P +
Sbjct: 1426 FRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCV 1485
Query: 72 DIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG 131
D C T +G C + G S C + +WG P C + N
Sbjct: 1486 DTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCC-SLGR-AWGNP-CE-LCPMANTT- 1540
Query: 132 AFECRCPPGYRLTPSLDEC--EDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTLREN- 187
+ CP G P+ ED+DEC + +C GDC NT GS++CEC PGY L E+
Sbjct: 1541 EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHT 1600
Query: 188 -VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF-KAGPNNDCVDVNECREGGMVC-- 243
+C D+DECS +C GTC N G Y C C + + N+C+D+ + VC
Sbjct: 1601 RICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKS-----VCFR 1655
Query: 244 -RNGRCRNTVGS--FRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGY 300
NG C+N + R C Y + C+ P P D C N G+
Sbjct: 1656 HYNGTCQNELAFNVTRKMCCCSYNIGQAWNR-----PCEACPTPISPDYQILCGNQAPGF 1710
Query: 301 ECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
G L D DEC E+P +CA G C N G + CECPAG+ ++ C D
Sbjct: 1711 LTDIHTGKPL------DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACED- 1763
Query: 361 RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG--M 418
DE + R P Q +C G+ RC ++ GG +
Sbjct: 1764 -----VDECGS----RESPCQ-QNADCINIPGSY------RCKCTRG---YKLSPGGACV 1804
Query: 419 GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRI 478
GR +ECR P+VC G C++T+GS+ C C G+ + D C+D DEC P
Sbjct: 1805 GR-------NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQP-- 1855
Query: 479 CGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAE--GRASCTF-RCHNTAGSFRCTC 535
CGNGTC N G Y C C PGF + CVD DEC G+ C F C NTAGSF C C
Sbjct: 1856 CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQV-CRFGHCLNTAGSFHCLC 1914
Query: 536 PYGYAVAADGVHCRDIDECVQEPRVC-PHACENVVGSYICKCPEGYRRTSAPQDSENACE 594
G+ + ADG +C D +EC+ C P C+N+ GS+ C CP G+ Q + C
Sbjct: 1915 QDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGF------QVQSDHCI 1968
Query: 595 DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEP 654
DI+EC E+ +LC G C N+ GSF C C GF S++G C D R C+ +G+C
Sbjct: 1969 DIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSV 2028
Query: 655 EXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTL--GAAWGSECELCPAPGSPARLDLC 712
+ TK +CCC+ G WG CELCP GS A +LC
Sbjct: 2029 PKAF--------------------NTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELC 2068
Query: 713 TAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCA-------PGRFRC 765
P D DV+ECA PG+C G FRC
Sbjct: 2069 ------PFGHGAVPGPD-------------DSREDVNECAENPGVCTNGVCVNTDGSFRC 2109
Query: 766 VCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
C GY G C D DEC+V P C N G ++C C G+E C D+D
Sbjct: 2110 ECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLM-MTCEDID 2168
Query: 824 ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 859
EC + C C NTEGSY C+C GY R D +
Sbjct: 2169 ECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAM 2204
Score = 380 bits (935), Expect = e-104
Identities = 219/596 (36%), Positives = 284/596 (47%), Gaps = 43/596 (7%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
CG+ G + P +DEC+ P++C G C + P G +C C G+ C D
Sbjct: 1181 CGQ--GYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVD 1238
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC--GDQRICDHGDC 167
VDEC C C N G+F C C GY + C DVDEC G H C
Sbjct: 1239 VDECDLNPHICLH-GDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASC 1297
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGP 226
N GS+ C C PG+ C D+DEC C G C N+PG+Y C C GF AG
Sbjct: 1298 LNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF-AGD 1356
Query: 227 NNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C D +EC E +C NG+C N G +RCEC G+ T D R C+DVDEC + + C
Sbjct: 1357 GFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ-GNLCA 1415
Query: 287 RDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
SC N G + C C G++L G C D +EC + P C G C N G Y+C C
Sbjct: 1416 FG---SCENLPGMFRCICNGGYELDRGGGNCTDINECAD-PVNCINGVCINTPGSYLCSC 1471
Query: 345 PAGWRFDKTAAVCVDERKELCY----DEWEAG-RCHRARPLQLARPECCCSEGAAWGRYC 399
P + + + CVD R C+ D ++G C + + R CCCS G AWG C
Sbjct: 1472 PQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPC 1531
Query: 400 ERCPAPDSAEFMRICQGGMG-RPN----LTQDLDECRVRPDVCVGGRCVNTDGSFRCECP 454
E CP ++ E+ +C GG G +PN + +D+DEC+ P +C GG CVNT GSF+CECP
Sbjct: 1532 ELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECP 1591
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ-GPDQTCVDVDEC 513
GY L+ C D DEC+ ICG GTC NT G Y C C + Q C+D+
Sbjct: 1592 PGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDM--- 1648
Query: 514 AEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVG-S 571
R S FR +N C + V C +I + P C AC +
Sbjct: 1649 ---RKSVCFRHYNGT----CQNELAFNVTRKMCCCSYNIGQAWNRP--C-EACPTPISPD 1698
Query: 572 YICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
Y C G + D DI+EC E +C+ G+CIN GSF C+C AGF
Sbjct: 1699 YQILC--GNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGF 1752
Score = 372 bits (914), Expect = e-102
Identities = 242/661 (36%), Positives = 302/661 (45%), Gaps = 88/661 (13%)
Query: 11 AGAVGVPQ----TKYLCCCSV--GHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNE 64
AG VP+ TK CCCS G WG PCE CP GS A LC G P +
Sbjct: 2023 AGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGP-DDS 2081
Query: 65 TKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+ ++EC P +C G C +T F+C C GY D T C D DECS G P C G
Sbjct: 2082 REDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP-C-GQG 2139
Query: 125 QCVNLPGAFECRCPPGYRLTPSLD-ECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYT 183
C N+ G FEC C G+ P L CED+DEC + C NT GSY C C GYT
Sbjct: 2140 TCTNVIGGFECACADGFE--PGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYT 2197
Query: 184 LREN--VCRDVDECSRPRPVC--RNGTCENLPGAYLCHCDDGFKA--GPNNDCVDVNECR 237
LRE+ +CRDVDEC+ + C R C+NL G + C C G + G C D NEC
Sbjct: 2198 LREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECH 2257
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE-----------CDELPHP-- 284
+C NGRC NT GSFRC+C G+ + C D+ + C L
Sbjct: 2258 AQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSE 2317
Query: 285 --------CG--RDGNPSCTNT----NGGYE--CSCGAGWKLVGRRCVDRDECKELPYVC 328
CG R P C Y C G+G+ GR D DEC+ L ++C
Sbjct: 2318 AVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGR---DVDECRMLAHLC 2374
Query: 329 AGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECC 388
A GEC N G + C C AG+ D TA C+D DE C Q+ +P C
Sbjct: 2375 AHGECINSLGSFRCHCQAGYTPDATATTCLD------MDE-----CS-----QVPKP-CT 2417
Query: 389 CSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGS 448
G + CP E + G +DLDEC R C CVNT G+
Sbjct: 2418 FLCKNTKGSFLCSCPRGYLLE-----EDG----RTCKDLDECTSRQHNCQF-LCVNTVGA 2467
Query: 449 FRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQ-GPDQT 506
F C CP G+ +C D DEC+ P CG +G C NT G + C+C GFT
Sbjct: 2468 FTCRCPPGFTQHHQ--ACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHG 2525
Query: 507 CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-C 565
C DV+EC +G C C N G +RC+CP G+ + C D +EC P C A C
Sbjct: 2526 CEDVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASC 2584
Query: 566 ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
N +G + C CP G+ A C+D++EC + CS C NT G FLC C G
Sbjct: 2585 RNTLGGFRCVCPSGFDFDQAL----GGCQDVDECAGRRGPCSYS-CANTPGGFLCGCPQG 2639
Query: 626 F 626
+
Sbjct: 2640 Y 2640
Score = 356 bits (876), Expect = 2e-97
Identities = 213/603 (35%), Positives = 278/603 (46%), Gaps = 41/603 (6%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC LC G C + P G++C C+ G++ C+DVDEC+ G G C N
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFG--SCEN 1421
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENV 188
LPG F C C GY L C D++EC D C +G C NT GSY C C + L +
Sbjct: 1422 LPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481
Query: 189 CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC 248
VD + C T + C + G + C + R G C
Sbjct: 1482 VGCVDTRAGN---CFLETHDRGDSGISCSAEIGVGVTRASCCCSLG--RAWGNPCELCPM 1536
Query: 249 RNTVGSFRCECAPGYTLTADGRNC--RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
NT +R C G + D+DEC ELP C + G+ C NT G ++C C
Sbjct: 1537 ANTT-EYRTLCPGGEGFQPNRITVILEDIDECQELPGLC-QGGD--CVNTFGSFQCECPP 1592
Query: 307 GWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKEL 364
G+ L R C D DEC +C G C N G Y C CPA + C+D RK +
Sbjct: 1593 GYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSV 1652
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMRICQGGMGRPN 422
C+ + G C + R CCCS G AW R CE CP P S ++ +C G
Sbjct: 1653 CFRHYN-GTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILC-GNQAPGF 1710
Query: 423 LTQ-------DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
LT D+DEC P +C G C+N GSFRCECP G+ L+C D DEC
Sbjct: 1711 LTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSR 1770
Query: 476 PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRC 533
C N C N G Y C+C+ G+ P CV +EC E C+ C +T GS+ C
Sbjct: 1771 ESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMC 1830
Query: 534 TCPYGYAVAADGVHCRDIDECVQEPRVCPH-ACENVVGSYICKCPEGYRRTSAPQDSENA 592
C G+ +AD C DIDEC ++P C + C+N++GSY C C G+ T
Sbjct: 1831 LCHRGFQASADQTLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGFVVT-----HNGD 1883
Query: 593 CEDINECEE-QEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGR 651
C D +EC +C G C+NT GSF C C GFE + DG +C+D T C ++G
Sbjct: 1884 CVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVD--TNECLS--LAGT 1939
Query: 652 CEP 654
C P
Sbjct: 1940 CLP 1942
Score = 343 bits (842), Expect = 2e-93
Identities = 209/655 (31%), Positives = 294/655 (44%), Gaps = 59/655 (9%)
Query: 9 SCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPI 68
SC+ +GV T+ CCCS+G AWG PCE CP + + LC G N +T + I
Sbjct: 1505 SCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDI 1564
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC +P LC+ G C +T FQC C GY + +C D+DECS C G C N
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGTCYN 1623
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTI--GSYRCECKPGYTLRE 186
G + C CP Y + C D+ + R +G C+N + R C Y + +
Sbjct: 1624 TLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHY-NGTCQNELAFNVTRKMCCCSYNIGQ 1682
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
R + C P C N +L G +D++EC E +C NG
Sbjct: 1683 AWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTG-------KPLDIDECGEIPAICANG 1735
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
C N +GSFRCEC G+ + C DVDEC PC + N C N G Y C C
Sbjct: 1736 ICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQ--NADCINIPGSYRCKCTR 1793
Query: 307 GWKL-VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
G+KL G CV R+EC+E+P VC+ G+C + G Y+C C G++ +C+D
Sbjct: 1794 GYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMD------ 1847
Query: 366 YDEWEAGRCHRARPLQ-LARPECCCSEG----------------AAWGRYCERCPAPDSA 408
DE + C + C C G G+ C ++A
Sbjct: 1848 IDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTA 1907
Query: 409 -EFMRICQGGM---GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
F +CQ G D +EC C+ G C N +GSFRC CP G+ + D
Sbjct: 1908 GSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSD-- 1965
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
C+D DEC+ +P +C GTC+N+ G ++C C PGF + C + R S C
Sbjct: 1966 HCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG-----HRCFDTRQSF---C 2017
Query: 525 HNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEP-RVCPHACENVVGSYICKCPEGYRR 582
+ +C+ P + C + E +P +CP + ++ CP G+
Sbjct: 2018 FTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCP---QEGSAAFQELCPFGHGA 2074
Query: 583 TSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
P DS ED+NEC E +C+ GVC+NTDGSF C+C G+ G +C+D
Sbjct: 2075 VPGPDDSR---EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVD 2126
Score = 337 bits (828), Expect = 1e-91
Identities = 216/646 (33%), Positives = 295/646 (45%), Gaps = 65/646 (10%)
Query: 23 CCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGT 82
CC ++G AWG+PCE C PA G VT + ++EC+ P +C G
Sbjct: 834 CCATLGAAWGSPCERCEI--DPACARGFARMTG-----VTCDD--VNECESFPGVCPNGR 884
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDV--DEC--SWGRPPCRGMAQCVNLPGAFE---C 135
C +T F+C C G D + LC DV + C W C V LPG + C
Sbjct: 885 CVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECG-----VTLPGKYRMDVC 939
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDEC 195
C G + C D + +C G +G + G +DV+EC
Sbjct: 940 CCSIGAVWGVECEACPDPESLEFASLCPRG-----LGFASRDFLSGRPFY----KDVNEC 990
Query: 196 SRPRPVCRNGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRNGRCRNTVGS 254
+C +GTC N G++ C C GF +C D++ECR +C G C NT GS
Sbjct: 991 KVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGS 1050
Query: 255 FRCECAPGYTLTAD-GRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV-- 311
F CEC PGY +NC DVDEC P C R G +CTNT+G Y+C C G +L
Sbjct: 1051 FECECFPGYESGFMLMKNCMDVDECARDPLLC-RGG--TCTNTDGSYKCQCPPGHELTAK 1107
Query: 312 GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK--------- 362
G C D DEC +C G+C N G + C C AG++ CVD +
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCD 1167
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCS---EGAAWGRYCERCPAPDSAEFMR-ICQGG- 417
C + + RC + L C+ E R C++ + R +C G
Sbjct: 1168 VHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGF 1227
Query: 418 MGRPNLTQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
M P++ D+DEC + P +C+ G C NT GSF C C GY++ C D DEC +
Sbjct: 1228 MATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVG 1287
Query: 476 PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFR 532
C + +C N G + C+C PG+ G C D+DEC C+ R C N GS+R
Sbjct: 1288 GHNCDSHASCLNIPGSFSCRCLPGWV-GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYR 1346
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSEN 591
CTC G+A DG C D DEC + +C + C N G Y C+C G+ P +
Sbjct: 1347 CTCRQGFA--GDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFD----PTEDHR 1400
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
AC+D++EC Q +LC+ G C N G F C C+ G+E G +C D
Sbjct: 1401 ACQDVDEC-AQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTD 1445
Score = 329 bits (808), Expect = 3e-89
Identities = 239/714 (33%), Positives = 308/714 (43%), Gaps = 111/714 (15%)
Query: 21 YLCCCSVGHAWGAPCEACPPRGSPAHTAL------CGEKPGEYINPV---------TNET 65
Y C C++G+ GA + C A +L C PG Y T
Sbjct: 705 YRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEIC 764
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS-WGR---PPCR 121
K +DEC P C G C + + C C G D + C D + + W + C
Sbjct: 765 KDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE 822
Query: 122 GMAQ--------CVNLPGAF-----ECR----CPPGYRLTPSLDECEDVDECGD-QRICD 163
Q C L A+ C C G+ + C+DV+EC +C
Sbjct: 823 VNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVT-CDDVNECESFPGVCP 881
Query: 164 HGDCRNTIGSYRCECKPGYTLREN--VCRDV-----------DECSRPRP--------VC 202
+G C NT GS+RCEC G L + +C DV DEC P C
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCC 941
Query: 203 RNGT-----CENLPG------AYLCHCDDGFKA----GPNNDCVDVNECREGGMVCRNGR 247
G CE P A LC GF + DVNEC+ +C +G
Sbjct: 942 SIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT 1001
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
CRNTVGSF C CA G+ L A RNC D+DEC P CG+ +C NT G +EC C G
Sbjct: 1002 CRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG---TCVNTPGSFECECFPG 1058
Query: 308 WK---LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKE 363
++ ++ + C+D DEC P +C GG C N +G Y C+CP G C D +
Sbjct: 1059 YESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECS 1118
Query: 364 L---------CYDEWEAGRC--HRARPLQLARPECC-CSEGAAWGRYCE-RCPAPDSAEF 410
L C + A +C H R C +E C+ C + +
Sbjct: 1119 LSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYR 1178
Query: 411 MRICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
QG P+ D+DEC P VC G C N G RC C DG++ PD +CVD
Sbjct: 1179 CSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVD 1238
Query: 469 ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFR--CH 525
DEC L+P IC +G C NT+G + C C G+ T C DVDEC G +C C
Sbjct: 1239 VDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCL 1298
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECV-QEPRVCPHA-CENVVGSYICKCPEGYRRT 583
N GSF C C G+ DG C D+DECV QE R P C NV GSY C C +G+
Sbjct: 1299 NIPGSFSCRCLPGWV--GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGD 1356
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
CED +EC E DLC G C+N G + C+C+ GF+P+ED C D
Sbjct: 1357 GF------FCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 290 bits (711), Expect = 2e-77
Identities = 192/556 (34%), Positives = 250/556 (44%), Gaps = 83/556 (14%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC + C GTC + GF+C C G+E C D+DECS C +C N
Sbjct: 2128 DECSV-GHPCGQGTCTNVIGGFECACADGFE-PGLMMTCEDIDECSLNPLLCA--FRCHN 2183
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICD-HG-DCRNTIGSYRCECKPGYTLR 185
G++ C CP GY L C DVDEC D Q+ C G +C+N IG++ C C PG
Sbjct: 2184 TEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPL 2243
Query: 186 ENV---CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF------------KAGP---- 226
C D +EC +C NG C N G++ C CD+GF + GP
Sbjct: 2244 PGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAE 2303
Query: 227 -----------NNDCVDVNECREGGMVCRNGRCRNT----VGSFRCECAPGYTLTADGRN 271
+++ V EC GG RC ++R C G TA+GR
Sbjct: 2304 VLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGR- 2362
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK--LVGRRCVDRDECKELPYVCA 329
DVDEC L H C C N+ G + C C AG+ C+D DEC ++P C
Sbjct: 2363 --DVDECRMLAHLCAHG---ECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCT 2417
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C+N G ++C CP G+ ++ C D DE + R H + L C
Sbjct: 2418 F-LCKNTKGSFLCSCPRGYLLEEDGRTCKD------LDECTS-RQHNCQFL------CVN 2463
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGS 448
+ GA + RCP P + + C D DEC +P C G C NT GS
Sbjct: 2464 TVGA----FTCRCP-PGFTQHHQACF----------DNDECSAQPGPCGAHGHCHNTPGS 2508
Query: 449 FRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-C 507
FRCEC G+ L G C D +EC P C +G C N GGY C C GFTQ C
Sbjct: 2509 FRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQC 2566
Query: 508 VDVDECAEGRASC-TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
VD +ECA +C + C NT G FRC CP G+ C+D+DEC C ++C
Sbjct: 2567 VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYSCA 2626
Query: 567 NVVGSYICKCPEGYRR 582
N G ++C CP+GY R
Sbjct: 2627 NTPGGFLCGCPQGYFR 2642
Score = 290 bits (711), Expect = 2e-77
Identities = 195/525 (37%), Positives = 244/525 (46%), Gaps = 87/525 (16%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC--RGMAQ 125
IDEC + P LC CH+T + C C GY +CRDVDEC+ G+ C RGM +
Sbjct: 2167 IDECSLNPLLCA-FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGM-E 2224
Query: 126 CVNLPGAFECRCPPGYRLTPSLDE-CEDVDECGDQR-ICDHGDCRNTIGSYRCECKPGY- 182
C NL G F C CPPG R P E C D +EC Q +C +G C NT GS+RC+C G+
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 183 ---TLRE---------------NVCRDVDECS----RPRPVCRNGT-----CE--NLPG- 212
TL E +CR + S R C G CE LPG
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGT 2344
Query: 213 -AYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRN 271
AY C G +G + DV+ECR +C +G C N++GSFRC C GYT A
Sbjct: 2345 SAYRKLCPHG--SGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATT 2402
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCA 329
C D+DEC ++P PC C NT G + CSC G+ L GR C D DEC + C
Sbjct: 2403 CLDMDECSQVPKPC----TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQ 2458
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C N G + C CP G+ + + C+D E A+P C
Sbjct: 2459 F-LCVNTVGAFTCRCPPGFT----------QHHQACFDNDECS----------AQPGPCG 2497
Query: 390 SEGAAWGRYCERCPAPDSAEFMR---ICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTD 446
+ G +C P E + + G G +D++EC P C G C N
Sbjct: 2498 AHG-----HCHNTPGSFRCECHQGFTLVSSGHG----CEDVNECD-GPHRCQHG-CQNQL 2546
Query: 447 GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT 506
G +RC CP G+ CVD +ECAL P CG+ +C NT GG+ C C GF DQ
Sbjct: 2547 GGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDF--DQA 2604
Query: 507 ---CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC 548
C DVDECA R C++ C NT G F C CP GY A G HC
Sbjct: 2605 LGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG-HC 2648
Score = 287 bits (704), Expect = 1e-76
Identities = 241/778 (30%), Positives = 309/778 (39%), Gaps = 109/778 (14%)
Query: 122 GMAQCVNLPGAFECR--CPPGYRLTPSLDECED---VDECGDQRICDHG-DCRN--TIGS 173
G +QCV +P CR C G+ P+L C D CG R C N T
Sbjct: 77 GRSQCV-VP---ICRRACGEGFCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMNGGTCRG 132
Query: 174 YRCECKPGYTLRENVCRDVDECSRPRPVCRNG-------TCENLPGAYLCHCDDGFKAGP 226
C C+ GYT VC C R C NG C + G C+ ++ GP
Sbjct: 133 ASCLCQKGYT--GTVCGQ-PICDRG---CHNGGRCIGPNRCACVYGFMGPQCERDYRTGP 186
Query: 227 NNDCVDVNECREG--GMVCRNGRCRNTVG---SFRCECAP--------GYTLTADGRNCR 273
V C+ G+VC C TVG CE P G+ C+
Sbjct: 187 CFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQ 246
Query: 274 DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPY-VCAGGE 332
DVDEC +P C G SC N G + C C G +L D + V GG
Sbjct: 247 DVDECQAVPGLC--QGG-SCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGR 303
Query: 333 CRNFNGGYV----CECPAG--WRFDKTAAVCV----DERKELCYDEWEAGRCHRAR-PLQ 381
C G+ C C G W +C +E ++LC H P
Sbjct: 304 CAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGL 363
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
L R + +G L Q +D CR ++C+ GR
Sbjct: 364 LGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGR 423
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
C+ T S+RCEC GY G C+D DEC P C +G C N G Y C+C PGF
Sbjct: 424 CLPTPSSYRCECNVGYTQDVRG-ECIDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQA 480
Query: 502 GPD-QTCVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPR 559
P Q CVDVDEC C RC NT GSF+C C G+ ++ DG +C D +EC
Sbjct: 481 TPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 560 VCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFL 619
C N GS+ C C G+ AP + C DI+EC + +C G C NT+GSF
Sbjct: 541 CVNGVCLNEDGSFSCLCKPGF--LLAP--GGHYCMDIDEC-QTPGICVNGHCTNTEGSFR 595
Query: 620 CDCDAGFEPSEDGTDCIDRRT-GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXG 678
C C G DG C+D TCY ++ G C G
Sbjct: 596 CQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSC--------------------ARPFPG 635
Query: 679 HVTKAQCCC-TLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXX 737
VTK++CCC +G C+LCPA S LC++
Sbjct: 636 TVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSS----------------GLGITTD 679
Query: 738 XXXXLDVFADVDECAAIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ 793
+ D + CA G+C G +RCVC GY +G+ C DVDECA+ CD
Sbjct: 680 GRDINECALDPEVCA--NGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDN 737
Query: 794 -LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
C N+ GSY C C G+ +D C+DVDEC + +C N GSY C C G
Sbjct: 738 GWCQNSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPG 794
Score = 263 bits (644), Expect = 2e-69
Identities = 204/618 (33%), Positives = 258/618 (41%), Gaps = 70/618 (11%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGA-PC-EACPPRGSPAHTALCGEK-------PGEYINP 60
CAG + T+ CCC G W A P E CPPRGS LC ++ PG +
Sbjct: 304 CAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGL 363
Query: 61 VTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+ + + + P P H + G + T+ L + +D C C
Sbjct: 364 LGFGSNGMGP-PLGPARLNP---HGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLC 419
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
+C+ P ++ C C GY EC DVDEC C HGDC N G+Y C C P
Sbjct: 420 LN-GRCLPTPSSYRCECNVGY-TQDVRGECIDVDECTSSP-CHHGDCVNIPGTYHCRCYP 476
Query: 181 GY--TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECR 237
G+ T C DVDEC +C G C N G++ C C+ GF+ P+ +CVD NEC
Sbjct: 477 GFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECA 536
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTN 297
M C NG C N GSF C C PG+ L G C D+DEC + P C N CTNT
Sbjct: 537 TSTM-CVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDEC-QTPGIC---VNGHCTNTE 591
Query: 298 GGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGEC-RNFNGGYV---CECP-AGWRF 350
G + C C G + GR CVD G C R F G C C F
Sbjct: 592 GSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGF 651
Query: 351 DKTAAVC----VDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPD 406
+ +C E + LC R PE C + R RC
Sbjct: 652 GEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNL 711
Query: 407 SAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
E G G+ D+DEC + +C G C N+ GS+ C CP G+ D C
Sbjct: 712 GYE-----AGASGKD--CTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEIC 764
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDE--C----AEGR-- 517
D DEC P C +G C N G Y C+C PG P T C+D + C E R
Sbjct: 765 KDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE 822
Query: 518 -----ASCTFRCHNTAGSF------RC----TCPYGYAVAADGVHCRDIDECVQEPRVCP 562
AS C T G+ RC C G+A GV C D++EC P VCP
Sbjct: 823 VNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFA-RMTGVTCDDVNECESFPGVCP 881
Query: 563 HA-CENVVGSYICKCPEG 579
+ C N GS+ C+CPEG
Sbjct: 882 NGRCVNTAGSFRCECPEG 899
Score = 258 bits (633), Expect = 5e-68
Identities = 221/687 (32%), Positives = 281/687 (40%), Gaps = 129/687 (18%)
Query: 40 PRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYE 99
P GS A + PG + ID C LC G C TP+ ++C C+ GY
Sbjct: 382 PHGSDAR-GIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYT 440
Query: 100 HDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GD 158
D C DVDEC+ PC CVN+PG + CRC PG++ TP+ C DVDEC
Sbjct: 441 QDVRGE-CIDVDECT--SSPCH-HGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVS 496
Query: 159 QRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLC 216
+C G C NT GS++C C G+ L + C D +EC+ +C NG C N G++ C
Sbjct: 497 GGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECA-TSTMCVNGVCLNEDGSFSC 555
Query: 217 HCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV 275
C GF P C+D++EC+ G +C NG C NT GSFRC+C G + DGR C D
Sbjct: 556 LCKPGFLLAPGGHYCMDIDECQTPG-ICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDT 614
Query: 276 ---DEC--------DELPHP---------CGRD----GNPS--CTNTNGG-YECSCGAGW 308
C P P C G P C N ++ C +G
Sbjct: 615 HVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGL 674
Query: 309 KLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCY 366
+ GR D +EC P VCA G C N G Y C C G+ + C D
Sbjct: 675 GITTDGR---DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTD------V 725
Query: 367 DEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM---GRPNL 423
DE C A C G +C+ P S C G +
Sbjct: 726 DE-----C--------ALNSLLCDNG-----WCQNSPGSYSCS----CPPGFHFWQDTEI 763
Query: 424 TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA---------DECAL 474
+D+DEC P CV G C N GS+ C+C G L P G C+D+ E
Sbjct: 764 CKDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRC 821
Query: 475 DPRICG---NGTCSNTRG---GYECQ-------CSPGFTQGPDQTCVDVDECAEGRASC- 520
+ + G C T G G C+ C+ GF + TC DV+EC C
Sbjct: 822 EVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCP 881
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRDI-----------DEC-VQEP-----RVCPH 563
RC NTAGSFRC CP G + A G C D+ DEC V P VC
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCC 941
Query: 564 ACENVVG------------SYICKCPEGYRRTSAP-QDSENACEDINECEEQEDLCSGGV 610
+ V G + CP G S +D+NEC+ LC+ G
Sbjct: 942 SIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT 1001
Query: 611 CINTDGSFLCDCDAGFEPSEDGTDCID 637
C NT GSF C C GF +C D
Sbjct: 1002 CRNTVGSFHCACAGGFALDAQERNCTD 1028
Score = 237 bits (580), Expect = 1e-61
Identities = 170/513 (33%), Positives = 219/513 (42%), Gaps = 93/513 (18%)
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGR 287
N +D+ CR +C NGRC T S+RCEC GYT G C DVDEC P G
Sbjct: 406 NQTIDI--CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDECTSSPCHHG- 461
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECP 345
C N G Y C C G++ R CVD DEC +C G C N G + C C
Sbjct: 462 ----DCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCN 517
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
AG+ CVD + C + + C +E ++ C+ P
Sbjct: 518 AGFELSPDGKNCVDHNE-----------CATST---MCVNGVCLNEDGSFSCLCK--PG- 560
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
F+ + GG + D+DEC+ P +CV G C NT+GSFRC+C G + DG
Sbjct: 561 ----FL-LAPGG----HYCMDIDECQT-PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRV 610
Query: 466 CVDA---DEC--ALDPRICGN---GT-------CSNTRGGY--ECQCSPGFTQGPDQTCV 508
CVD C A++ C GT C+N G+ CQ P Q
Sbjct: 611 CVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALC 670
Query: 509 -----------DVDECAEGRASCTFR-CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
D++ECA C C N GS+RC C GY A G C D+DEC
Sbjct: 671 SSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECAL 730
Query: 557 EPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTD 615
+C + C+N GSY C CP G+ QD+E C+D++EC C GVC N
Sbjct: 731 NSLLCDNGWCQNSPGSYSCSCPPGFHFW---QDTE-ICKDVDECLSSP--CVSGVCRNLA 784
Query: 616 GSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXX 675
GS+ C C G GT C+D GTC+ + RCE
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE--------------------VN 824
Query: 676 XXGHVTKAQCCCTLGAAWGSECELCPAPGSPAR 708
G +++CC TLGAAWGS CE C + AR
Sbjct: 825 LQGASLRSECCATLGAAWGSPCERCEIDPACAR 857
Score = 212 bits (517), Expect = 5e-54
Identities = 157/523 (30%), Positives = 203/523 (38%), Gaps = 74/523 (14%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAW---GAPC----------EACPPRGSPAH----TALCGE 52
CA + YLC C G+ GA C + C RG T C
Sbjct: 2177 CAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVC 2236
Query: 53 KPGEYINPVTNETKPID-ECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVD 111
PG P + E D EC P LC G C +T F+C CD G++ T C D+
Sbjct: 2237 PPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIR 2296
Query: 112 E----CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDC 167
+ + CR ++ EC C G P + C +++C HG
Sbjct: 2297 QGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGS- 2355
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN 227
GYT RDVDEC +C +G C N G++ CHC G+
Sbjct: 2356 -------------GYTAEG---RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDAT 2399
Query: 228 -NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C+D++EC + C C+NT GSF C C GY L DGR C+D+DEC H C
Sbjct: 2400 ATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNC- 2457
Query: 287 RDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVC-AGGECRNFNGGYVCECP 345
C NT G + C C G+ + C D DEC P C A G C N G + CEC
Sbjct: 2458 ---QFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECH 2514
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
G+ + C D + C RC QL C C +G +C
Sbjct: 2515 QGFTLVSSGHGCEDVNE--CDGPH---RCQHGCQNQLGGYRCSCPQGFTQHSQWAQCV-- 2567
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
D +EC + P C C NT G FRC CP G+
Sbjct: 2568 --------------------DENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGG 2607
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV 508
C D DECA C +C+NT GG+ C C G+ + CV
Sbjct: 2608 CQDVDECAGRRGPCSY-SCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 180 bits (438), Expect = 2e-44
Identities = 99/242 (40%), Positives = 122/242 (50%), Gaps = 22/242 (9%)
Query: 414 CQGGMGRPNLTQ----DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
CQ G P+ T D+DEC P C C NT GSF C CP GY+L DG +C D
Sbjct: 2390 CQAGY-TPDATATTCLDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDL 2447
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNT 527
DEC C C NT G + C+C PGFTQ Q C D DEC+ C CHNT
Sbjct: 2448 DECTSRQHNC-QFLCVNTVGAFTCRCPPGFTQH-HQACFDNDECSAQPGPCGAHGHCHNT 2505
Query: 528 AGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQ 587
GSFRC C G+ + + G C D++EC P C H C+N +G Y C CP+G+ + S Q
Sbjct: 2506 PGSFRCECHQGFTLVSSGHGCEDVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHS--Q 2562
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE------PSEDGTDCIDRRTG 641
++ C D NEC C C NT G F C C +GF+ +D +C RR G
Sbjct: 2563 WAQ--CVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRR-G 2619
Query: 642 TC 643
C
Sbjct: 2620 PC 2621
Score = 98.7 bits (235), Expect = 8e-20
Identities = 116/418 (27%), Positives = 158/418 (37%), Gaps = 56/418 (13%)
Query: 250 NTVGS-FRCECAPGYTLTADGRNCRDVDECDELPHPCGRD--GNPS-CTNTNGGYECSCG 305
N GS F C PG+ T GR+ V C CG P+ CT +G SCG
Sbjct: 58 NVCGSRFHAYCCPGWR-TFPGRSQCVVPICRRA---CGEGFCSQPNLCTCADGTLAPSCG 113
Query: 306 AG-WKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCE--CPAGWR-FDKTAAVCV--- 358
C++ C+ +C G G +C+ C G R CV
Sbjct: 114 VSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCACVYGF 173
Query: 359 -------DERKELCYDEWEAGRC-HRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
D R C+ + C H+ L + CC + G AWG CE CPA
Sbjct: 174 MGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHP-- 231
Query: 411 MRICQGGMGRPNL----TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
C+ G PN+ QD+DEC+ P +C GG CVN GSF C CP G+ L+ +C
Sbjct: 232 ---CRRGF-IPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAAC 287
Query: 467 VDADECALDPRICGNGTCSNTRGGY----ECQCSPG--FTQGPDQTCVDVDECAEGRASC 520
D A + G G C+ G+ +C C G + GP E + C
Sbjct: 288 EDYRAGACFSVLFG-GRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLC 346
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPE-G 579
R G P G G + + R+ PH GS P G
Sbjct: 347 AQRLPLLPGH-----P-GLFPGLLGFGSNGMGPPLGPARLNPH------GSDARGIPSLG 394
Query: 580 YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
++ + N DI C +LC G C+ T S+ C+C+ G+ G +CID
Sbjct: 395 PGNSNIGTATLNQTIDI--CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRG-ECID 449
Score = 98.3 bits (234), Expect = 1e-19
Identities = 46/113 (40%), Positives = 57/113 (50%), Gaps = 9/113 (7%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL--CHNT 798
D+DEC + C G F C C PG+ + C D DEC+ +P PC CHNT
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNT 2505
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
GS+ C C G+ L G C DV+EC+ H CQ C N G Y CSC G+
Sbjct: 2506 PGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHGCQNQLGGYRCSCPQGF 2557
Score = 97.9 bits (233), Expect = 1e-19
Identities = 51/124 (41%), Positives = 61/124 (49%), Gaps = 11/124 (8%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHN 797
D DECA LC APG +RC C G+ P + C DVDECA C N
Sbjct: 1362 DRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCEN 1421
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRG 855
G + C+C GYELD G NC D++EC + +C NT GSY CSC +E G
Sbjct: 1422 LPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481
Query: 856 DACV 859
CV
Sbjct: 1482 VGCV 1485
Score = 89.0 bits (211), Expect = 6e-17
Identities = 39/103 (37%), Positives = 54/103 (52%), Gaps = 4/103 (3%)
Query: 761 GRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDEDGA 817
G +RC C G+ + C D +ECA+ PP C C NT G + C+C +G++ D+
Sbjct: 2547 GGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALG 2606
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
C+DVDEC C C+NT G + C C GY + G CV
Sbjct: 2607 GCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 84.2 bits (199), Expect = 2e-15
Identities = 49/125 (39%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQ--LC 795
DVDEC P +C G F C C GY R C+DVDEC V CD C
Sbjct: 1238 DVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASC 1297
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEK 853
N GS+ C C G+ DG C D+DEC H C C N GSY C+C G+
Sbjct: 1298 LNIPGSFSCRCLPGWV--GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355
Query: 854 RGDAC 858
G C
Sbjct: 1356 DGFFC 1360
Score = 80.6 bits (190), Expect = 2e-14
Identities = 44/117 (37%), Positives = 53/117 (45%), Gaps = 12/117 (10%)
Query: 747 DVDECAAIPGLCA--------PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCH 796
D DEC+A PG C PG FRC C G+ +G C DV+EC P C C
Sbjct: 2485 DNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHGCQ 2543
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYE 852
N G Y C C G+ A C D +EC TC C NT G + C C G++
Sbjct: 2544 NQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFD 2600
Score = 73.3 bits (172), Expect = 3e-12
Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 7/95 (7%)
Query: 15 GVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIM 74
G+ TK LCC +VG AWG PCE CP + P + G N T + +DEC +
Sbjct: 202 GLVCTKALCCATVGRAWGLPCELCPAQPHPC-------RRGFIPNIHTGACQDVDECQAV 254
Query: 75 PQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
P LC+ G+C + F C C G+ ++S C D
Sbjct: 255 PGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 70.9 bits (166), Expect = 2e-11
Identities = 45/120 (37%), Positives = 58/120 (48%), Gaps = 12/120 (10%)
Query: 751 CAAIPGLCAPGRFRCVCG---PGYRP---AGEVCADVDECAVRPPPC-DQLCHNTDGSYD 803
C A P +P ++ +CG PG+ G+ D+DEC P C + +C N GS+
Sbjct: 1688 CEACPTPISPD-YQILCGNQAPGFLTDIHTGKPL-DIDECGEIPAICANGICINQIGSFR 1745
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE-KRGDACVG 860
C C G+ + C DVDEC CQQ C N GSY C C GY+ G ACVG
Sbjct: 1746 CECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVG 1805
Score = 50.4 bits (115), Expect = 3e-05
Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 32/149 (21%)
Query: 743 DVFADVDECAAIP---GLCA--PGRFRCVCGPGYR--PAGEVCADVDE--C--AVRPPPC 791
++ DVDEC + P G+C G + C CGPG R P+G C D + C ++ C
Sbjct: 762 EICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRC 821
Query: 792 DQLCHNTDGSYDCLCRTGY---------ELDE---------DGANCRDVDECERDTHTCQ 833
+ +C G E+D G C DV+ECE C
Sbjct: 822 EVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCP 881
Query: 834 Q-ICSNTEGSYECSCEDG--YEKRGDACV 859
C NT GS+ C C +G + G CV
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCV 910
Score = 48.0 bits (109), Expect = 1e-04
Identities = 57/195 (29%), Positives = 74/195 (37%), Gaps = 34/195 (17%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
GTC G C C GY T +C C G C +C+ G C C G
Sbjct: 128 GTCR----GASCLCQKGY----TGTVCGQ-PICDRG---CHNGGRCI---GPNRCACVYG 172
Query: 141 YRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRP 200
+ + P +CE D R G C +G C+ + L VC C+
Sbjct: 173 F-MGP---QCER-----DYRT---GPCFGQVGPEGCQ----HQLTGLVCTKALCCATVGR 216
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCEC 259
CE P A C GF + C DV+EC+ +C+ G C N VGSF C C
Sbjct: 217 AW-GLPCELCP-AQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRC 274
Query: 260 APGYTLTADGRNCRD 274
G+ L+ C D
Sbjct: 275 PVGHRLSDSSAACED 289
Score = 38.7 bits (86), Expect = 0.087
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGY 851
CR G+ + C+DVDEC+ CQ C N GS+ C C G+
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGH 278
>AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 2 protein.
Length = 2809
Score = 728 bits (1799), Expect = 0.0
Identities = 355/869 (40%), Positives = 460/869 (52%), Gaps = 64/869 (7%)
Query: 9 SCAGAVGVPQTKYLCCCS--VGHAWGAPCEACPPRGSPAHTALCGEK-PGEYINPVTNET 65
+C + T+ +CCCS +G AW PCEACP SP + LCG + PG + T +
Sbjct: 1660 TCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKP 1719
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ 125
IDEC +P +C G C + F+C C G+ +++ C DVDEC PC+ A
Sbjct: 1720 LDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCECKPGY-- 182
C+N+PG++ C+C GY+L+P C +EC + +C HGDC +T GSY C C G+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPG-GACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQA 1838
Query: 183 TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE-GGM 241
+ + +C D+DEC R +P C NGTC+N+ G+Y C C GF N DCVD +EC G
Sbjct: 1839 SADQTLCMDIDECDR-QP-CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 242 VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
VCR G C NT GSF C C G+ LTADG+NC D +EC L C G +C N G +
Sbjct: 1897 VCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTC-LPG--TCQNLEGSFR 1953
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER 361
C C G+++ C+D DEC E P +C G C N G + C CP G+ C D R
Sbjct: 1954 CICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTR 2013
Query: 362 KELCYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMRICQGGMG 419
+ C+ +EAG+C + + CCCS+ G WG CE CP SA F +C G G
Sbjct: 2014 QSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHG 2073
Query: 420 R----PNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
+ +D++EC P VC G CVNTDGSFRCECP GY L G++CVD DEC++
Sbjct: 2074 AVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG 2133
Query: 476 PRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
CG GTC+N GG+EC C+ GF G TC D+DEC+ C FRCHNT GS+ CTC
Sbjct: 2134 -HPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTC 2192
Query: 536 PYGYAVAADGVHCRDIDECVQEPRVCPHA----CENVVGSYICKCPEGYRRTSAPQDSEN 591
P GY + DG CRD+DEC + C HA C+N++G++ C CP G R P E
Sbjct: 2193 PAGYTLREDGAMCRDVDECADGQQDC-HARGMECKNLIGTFACVCPPGMR--PLPGSGE- 2248
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGR 651
C D NEC Q DLC G C+NT GSF CDCD GF+PS T+C D R G C+ ++
Sbjct: 2249 GCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTM 2308
Query: 652 CEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDL 711
C VT+A+CCC G WG CELCP PG+ A L
Sbjct: 2309 CR------------------SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKL 2350
Query: 712 CTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCAPGRFRCVCGPGY 771
C + A + CA + + G FRC C GY
Sbjct: 2351 CP--------------HGSGYTAEGRDVDECRMLAHL--CAHGECINSLGSFRCHCQAGY 2394
Query: 772 RP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDT 829
P C D+DEC+ P PC LC NT GS+ C C GY L+EDG C+D+DEC
Sbjct: 2395 TPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQ 2454
Query: 830 HTCQQICSNTEGSYECSCEDGYEKRGDAC 858
H CQ +C NT G++ C C G+ + AC
Sbjct: 2455 HNCQFLCVNTVGAFTCRCPPGFTQHHQAC 2483
Score = 458 bits (1129), Expect = e-128
Identities = 268/748 (35%), Positives = 343/748 (45%), Gaps = 83/748 (11%)
Query: 151 EDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTLR-ENVCRDVDECSRPRPVCRNGTCE 208
+ +D C +C +G C T SYRCEC GYT C DVDEC+ C +G C
Sbjct: 407 QTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSP--CHHGDCV 464
Query: 209 NLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTA 267
N+PG Y C C GF+A P CVDV+EC G +C GRC NT GSF+C C G+ L+
Sbjct: 465 NIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSP 524
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELP 325
DG+NC D +EC C N C N +G + C C G+ L G C+D DEC + P
Sbjct: 525 DGKNCVDHNEC-ATSTMCV---NGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDEC-QTP 579
Query: 326 YVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER-KELCYDEWEAGRCHRARPLQLAR 384
+C G C N G + C+C G VCVD + CY E G C R P + +
Sbjct: 580 GICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTK 639
Query: 385 PECCCSE-GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCV 443
ECCC+ +G C+ CPA +SAEF +C G+G +D++EC + P+VC G C
Sbjct: 640 SECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCE 699
Query: 444 NTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
N GS+RC C GY G C D DECAL+ +C NG C N+ G Y C C PGF
Sbjct: 700 NLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQ 759
Query: 504 D-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP 562
D + C DVDEC + C N AGS+ C C G + G C D + ++
Sbjct: 760 DTEICKDVDECLSS-PCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQE 818
Query: 563 HACE-NVVGSYI---CKCPEGYRRTSAPQDSE--------------NACEDINECEEQED 604
CE N+ G+ + C G S + E C+D+NECE
Sbjct: 819 SRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPG 878
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXX 664
+C G C+NT GSF C+C G G C+D R C+ C
Sbjct: 879 VCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDEC------------ 926
Query: 665 XXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXX 724
G CCC++GA WG ECE CP P S LC
Sbjct: 927 --------GVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCP----------- 967
Query: 725 XXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLC-------APGRFRCVCGPGYRPAGEV 777
+ DV+EC PGLC G F C C G+ +
Sbjct: 968 ----RGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQE 1023
Query: 778 --CADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD-EDGANCRDVDECERDTHTCQ 833
C D+DEC + P C Q C NT GS++C C GYE NC DVDEC RD C+
Sbjct: 1024 RNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCR 1083
Query: 834 -QICSNTEGSYECSCEDGYE--KRGDAC 858
C+NT+GSY+C C G+E +G AC
Sbjct: 1084 GGTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Score = 442 bits (1090), Expect = e-123
Identities = 286/830 (34%), Positives = 359/830 (43%), Gaps = 101/830 (12%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+DEC P LC+ GTC +T ++C C G+E C D+DECS C QCV
Sbjct: 1072 VDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH-GQCV 1130
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
N+ GAF+C C G++ TP C D++EC Q C NT GSYRC C GY+L +
Sbjct: 1131 NVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPD 1190
Query: 188 --VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCR 244
C DVDEC VC G C N+PG + C C DGF A P+ CVDV+EC +C
Sbjct: 1191 GRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICL 1250
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
+G C NT GSF C C GY + C DVDEC+ H C D + SC N G + C C
Sbjct: 1251 HGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNC--DSHASCLNIPGSFSCRC 1308
Query: 305 GAGWKLVGRRCVDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
GW G C D DEC + C+ G+C N G Y C C G+ D DE E
Sbjct: 1309 LPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAE 1368
Query: 364 --------LCYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMR- 412
C + RC C + A G C + R
Sbjct: 1369 NVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRC 1428
Query: 413 ICQGGM----GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
IC GG G N T D++EC P C+ G C+NT GS+ C CP + L P G+ CVD
Sbjct: 1429 ICNGGYELDRGGGNCT-DINEC-ADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVD 1486
Query: 469 --ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRA---SCTFR 523
A C L+ G+ G C G C C+ GRA C
Sbjct: 1487 TRAGNCFLETHDRGDS-------GISCSAEIGVGVTRASCC-----CSLGRAWGNPCELC 1534
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHC--RDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
+R CP G + + DIDEC + P +C C N GS+ C+CP GY
Sbjct: 1535 PMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGY 1594
Query: 581 RRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRT 640
+ + CEDI+EC +C G C NT G++ C C A + G +C+D R
Sbjct: 1595 HLS----EHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRK 1650
Query: 641 GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCT--LGAAWGSECE 698
C+R +G C+ E +VT+ CCC+ +G AW CE
Sbjct: 1651 SVCFRH-YNGTCQNELAF--------------------NVTRKMCCCSYNIGQAWNRPCE 1689
Query: 699 LCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLC 758
CP P SP LC N P D+DEC IP +C
Sbjct: 1690 ACPTPISPDYQILCG--NQAPGFLTDIHTGKP---------------LDIDECGEIPAIC 1732
Query: 759 AP-------GRFRCVCGPG--YRPAGEVCADVDECAVRPPPCDQL--CHNTDGSYDCLCR 807
A G FRC C G Y C DVDEC R PC Q C N GSY C C
Sbjct: 1733 ANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCT 1792
Query: 808 TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
GY+L GA C +EC + C C +TEGSY C C G++ D
Sbjct: 1793 RGYKLSPGGA-CVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASAD 1841
Score = 430 bits (1060), Expect = e-120
Identities = 232/592 (39%), Positives = 291/592 (49%), Gaps = 47/592 (7%)
Query: 1 MEWNEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
+ W+E++ C + +CCCS+G WG CEACP S +LC G
Sbjct: 919 LRWDEDE--CGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRD 976
Query: 61 VTNET---KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGR 117
+ K ++EC + P LC GTC +T F C C G+ D C D+DEC
Sbjct: 977 FLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISP 1036
Query: 118 PPCRGMAQCVNLPGAFECRCPPGYRLTPSL-DECEDVDECG-DQRICDHGDCRNTIGSYR 175
C G CVN PG+FEC C PGY L C DVDEC D +C G C NT GSY+
Sbjct: 1037 DLC-GQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYK 1095
Query: 176 CECKPGY--TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVD 232
C+C PG+ T + C D+DECS +C +G C N+ GA+ C C GF++ P+ CVD
Sbjct: 1096 CQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVD 1155
Query: 233 VNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
+NECR C + C NT GS+RC C GY+L DGR C DVDEC+E P C +
Sbjct: 1156 INECRVQNGGC-DVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQG---H 1211
Query: 293 CTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRF 350
CTN GG+ C C G+ R CVD DEC P++C G+C N G +VC C G+
Sbjct: 1212 CTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMV 1271
Query: 351 DKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
K A C D DE E G H C A+ C P S
Sbjct: 1272 RKGATGCSD------VDECEVGG-HN------------CDSHAS----CLNIPGSFSC-- 1306
Query: 411 MRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
R G +G DLDEC + C G C+N GS+RC C G+ A DG C D
Sbjct: 1307 -RCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCEDR 1363
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTA 528
DECA + +C NG C N GGY C+C GF D + C DVDECA+G C N
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLP 1423
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGY 580
G FRC C GY + G +C DI+EC C N GSY+C CP+ +
Sbjct: 1424 GMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDF 1475
Score = 409 bits (1007), Expect = e-113
Identities = 300/917 (32%), Positives = 373/917 (40%), Gaps = 98/917 (10%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPID 69
C VG Q C V +PC P T C PG P +D
Sbjct: 433 CECNVGYTQDVRGECIDVDECTSSPCHHGDCVNIPG-TYHCRCYPGFQATPTRQACVDVD 491
Query: 70 ECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
EC + LC G C +T FQC C+ G+E C D +EC+ G+ C+N
Sbjct: 492 ECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGV--CLNE 549
Query: 130 PGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN-- 187
G+F C C PG+ L P C D+DEC IC +G C NT GS+RC+C G + +
Sbjct: 550 DGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGR 609
Query: 188 VCRDVD------------ECSRPRP--VCRNGTCENLPG------AYLCHCDDG--FKA- 224
VC D C+RP P V ++ C P LC + F+A
Sbjct: 610 VCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQAL 669
Query: 225 -----GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECD 279
G D D+NEC VC NG C N GS+RC C GY A G++C DVDEC
Sbjct: 670 CSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECA 729
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFN 337
C N C N+ G Y CSC G+ C D DEC P C G CRN
Sbjct: 730 LNSLLCD---NGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLA 784
Query: 338 GGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGR 397
G Y C+C G R D + C+D K C+ + + RC R ECC + GAAWG
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGS 844
Query: 398 YCERCPAPDSAEFMRICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPD 455
CERC E C G R D++EC P VC GRCVNT GSFRCECP+
Sbjct: 845 PCERC------EIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPE 898
Query: 456 GYVLAPDGLSCVDA--DECAL--DPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDV 510
G +L G CVD + C L D CG R C CS G G + + C D
Sbjct: 899 GLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDV-CCCSIGAVWGVECEACPD- 956
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH-ACENVV 569
E E + C + F P+ +D++EC P +C H C N V
Sbjct: 957 PESLEFASLCPRGLGFASRDFLSGRPF----------YKDVNECKVFPGLCTHGTCRNTV 1006
Query: 570 GSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP- 628
GS+ C C G+ A E C DI+EC DLC G C+NT GSF C+C G+E
Sbjct: 1007 GSFHCACAGGF----ALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESG 1062
Query: 629 ----------SEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXG 678
E D + R GTC + S +C+ G
Sbjct: 1063 FMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDG 1122
Query: 679 HVTKAQCCCTLGAAWGS-ECELCPAPGSPARLDL--CTAVNLTPXXXXXXXXXXXXXXXX 735
QC +GA S P +D+ C N
Sbjct: 1123 LCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCG 1182
Query: 736 XXXXXXLD--VFADVDECAAIPGLC-------APGRFRCVCGPGY--RPAGEVCADVDEC 784
D ADVDEC P +C PG RC+C G+ P C DVDEC
Sbjct: 1183 QGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDEC 1242
Query: 785 AVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEG 841
+ P C C NT GS+ C C+ GY + + C DVDECE H C C N G
Sbjct: 1243 DLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPG 1302
Query: 842 SYECSCEDGYEKRGDAC 858
S+ C C G+ G C
Sbjct: 1303 SFSCRCLPGWVGDGFEC 1319
Score = 405 bits (996), Expect = e-112
Identities = 224/611 (36%), Positives = 293/611 (47%), Gaps = 53/611 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDE--------------- 112
IDEC P LC GTC ++P FQC C G+ + H C D +
Sbjct: 1970 IDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVP 2029
Query: 113 ---------CSWGRPPCRGMAQ-CVNLP----GAFECRCPPGYRLTPSLDEC-EDVDECG 157
C + P G C P AF+ CP G+ P D+ EDV+EC
Sbjct: 2030 KAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECA 2089
Query: 158 DQR-ICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAY 214
+ +C +G C NT GS+RCEC GY+L C D DECS P C GTC N+ G +
Sbjct: 2090 ENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP-CGQGTCTNVIGGF 2148
Query: 215 LCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRD 274
C C DGF+ G C D++EC ++C RC NT GS+ C C GYTL DG CRD
Sbjct: 2149 ECACADGFEPGLMMTCEDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Query: 275 VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV---GRRCVDRDECKELPYVCAGG 331
VDEC + C G C N G + C C G + + G C D +EC P +C G
Sbjct: 2208 VDECADGQQDCHARGM-ECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNG 2266
Query: 332 ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLA--RPECCC 389
C N G + C+C G++ T C D R+ C+ E C A R ECCC
Sbjct: 2267 RCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCC 2326
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
G WG CE CP P ++ + ++C G G +D+DECR+ +C G C+N+ GSF
Sbjct: 2327 GGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSF 2386
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCV 508
RC C GY +C+D DEC+ P+ C C NT+G + C C G+ D +TC
Sbjct: 2387 RCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCK 2445
Query: 509 DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC-PHA-CE 566
D+DEC + +C F C NT G+F C CP G+ C D DEC +P C H C
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQA--CFDNDECSAQPGPCGAHGHCH 2503
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
N GS+ C+C +G+ S S + CED+NEC+ C G C N G + C C GF
Sbjct: 2504 NTPGSFRCECHQGFTLVS----SGHGCEDVNECDGPH-RCQHG-CQNQLGGYRCSCPQGF 2557
Query: 627 EPSEDGTDCID 637
C+D
Sbjct: 2558 TQHSQWAQCVD 2568
Score = 395 bits (972), Expect = e-109
Identities = 287/876 (32%), Positives = 377/876 (43%), Gaps = 134/876 (15%)
Query: 21 YLCCCSVGHAW---GAPCEACPPRGSPAH--TALCGEKPGEYIN--PVTNETKP--IDEC 71
+ C C+ G+ G C P + +C PG Y+ P E P +
Sbjct: 1426 FRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCV 1485
Query: 72 DIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG 131
D C T +G C + G S C + +WG P C + N
Sbjct: 1486 DTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCC-SLGR-AWGNP-CE-LCPMANTT- 1540
Query: 132 AFECRCPPGYRLTPSLDEC--EDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTLREN- 187
+ CP G P+ ED+DEC + +C GDC NT GS++CEC PGY L E+
Sbjct: 1541 EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHT 1600
Query: 188 -VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF-KAGPNNDCVDVNECREGGMVC-- 243
+C D+DECS +C GTC N G Y C C + + N+C+D+ + VC
Sbjct: 1601 RICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKS-----VCFR 1655
Query: 244 -RNGRCRNTVGS--FRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGY 300
NG C+N + R C Y + C+ P P D C N G+
Sbjct: 1656 HYNGTCQNELAFNVTRKMCCCSYNIGQAWNR-----PCEACPTPISPDYQILCGNQAPGF 1710
Query: 301 ECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
G L D DEC E+P +CA G C N G + CECPAG+ ++ C D
Sbjct: 1711 LTDIHTGKPL------DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACED- 1763
Query: 361 RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG--M 418
DE + R P Q +C G+ RC ++ GG +
Sbjct: 1764 -----VDECGS----RESPCQ-QNADCINIPGSY------RCKCTRG---YKLSPGGACV 1804
Query: 419 GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRI 478
GR +ECR P+VC G C++T+GS+ C C G+ + D C+D DEC P
Sbjct: 1805 GR-------NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQP-- 1855
Query: 479 CGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAE--GRASCTF-RCHNTAGSFRCTC 535
CGNGTC N G Y C C PGF + CVD DEC G+ C F C NTAGSF C C
Sbjct: 1856 CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQV-CRFGHCLNTAGSFHCLC 1914
Query: 536 PYGYAVAADGVHCRDIDECVQEPRVC-PHACENVVGSYICKCPEGYRRTSAPQDSENACE 594
G+ + ADG +C D +EC+ C P C+N+ GS+ C CP G+ Q + C
Sbjct: 1915 QDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGF------QVQSDHCI 1968
Query: 595 DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEP 654
DI+EC E+ +LC G C N+ GSF C C GF S++G C D R C+ +G+C
Sbjct: 1969 DIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSV 2028
Query: 655 EXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTL--GAAWGSECELCPAPGSPARLDLC 712
+ TK +CCC+ G WG CELCP GS A +LC
Sbjct: 2029 PKAF--------------------NTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELC 2068
Query: 713 TAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCA-------PGRFRC 765
P D DV+ECA PG+C G FRC
Sbjct: 2069 ------PFGHGAVPGPD-------------DSREDVNECAENPGVCTNGVCVNTDGSFRC 2109
Query: 766 VCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
C GY G C D DEC+V P C N G ++C C G+E C D+D
Sbjct: 2110 ECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLM-MTCEDID 2168
Query: 824 ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 859
EC + C C NTEGSY C+C GY R D +
Sbjct: 2169 ECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAM 2204
Score = 380 bits (935), Expect = e-104
Identities = 219/596 (36%), Positives = 284/596 (47%), Gaps = 43/596 (7%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
CG+ G + P +DEC+ P++C G C + P G +C C G+ C D
Sbjct: 1181 CGQ--GYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVD 1238
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC--GDQRICDHGDC 167
VDEC C C N G+F C C GY + C DVDEC G H C
Sbjct: 1239 VDECDLNPHICLH-GDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASC 1297
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGP 226
N GS+ C C PG+ C D+DEC C G C N+PG+Y C C GF AG
Sbjct: 1298 LNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF-AGD 1356
Query: 227 NNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C D +EC E +C NG+C N G +RCEC G+ T D R C+DVDEC + + C
Sbjct: 1357 GFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ-GNLCA 1415
Query: 287 RDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
SC N G + C C G++L G C D +EC + P C G C N G Y+C C
Sbjct: 1416 FG---SCENLPGMFRCICNGGYELDRGGGNCTDINECAD-PVNCINGVCINTPGSYLCSC 1471
Query: 345 PAGWRFDKTAAVCVDERKELCY----DEWEAG-RCHRARPLQLARPECCCSEGAAWGRYC 399
P + + + CVD R C+ D ++G C + + R CCCS G AWG C
Sbjct: 1472 PQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPC 1531
Query: 400 ERCPAPDSAEFMRICQGGMG-RPN----LTQDLDECRVRPDVCVGGRCVNTDGSFRCECP 454
E CP ++ E+ +C GG G +PN + +D+DEC+ P +C GG CVNT GSF+CECP
Sbjct: 1532 ELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECP 1591
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ-GPDQTCVDVDEC 513
GY L+ C D DEC+ ICG GTC NT G Y C C + Q C+D+
Sbjct: 1592 PGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDM--- 1648
Query: 514 AEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVG-S 571
R S FR +N C + V C +I + P C AC +
Sbjct: 1649 ---RKSVCFRHYNGT----CQNELAFNVTRKMCCCSYNIGQAWNRP--C-EACPTPISPD 1698
Query: 572 YICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
Y C G + D DI+EC E +C+ G+CIN GSF C+C AGF
Sbjct: 1699 YQILC--GNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGF 1752
Score = 372 bits (914), Expect = e-102
Identities = 242/661 (36%), Positives = 302/661 (45%), Gaps = 88/661 (13%)
Query: 11 AGAVGVPQ----TKYLCCCSV--GHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNE 64
AG VP+ TK CCCS G WG PCE CP GS A LC G P +
Sbjct: 2023 AGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGP-DDS 2081
Query: 65 TKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+ ++EC P +C G C +T F+C C GY D T C D DECS G P C G
Sbjct: 2082 REDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP-C-GQG 2139
Query: 125 QCVNLPGAFECRCPPGYRLTPSLD-ECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYT 183
C N+ G FEC C G+ P L CED+DEC + C NT GSY C C GYT
Sbjct: 2140 TCTNVIGGFECACADGFE--PGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYT 2197
Query: 184 LREN--VCRDVDECSRPRPVC--RNGTCENLPGAYLCHCDDGFKA--GPNNDCVDVNECR 237
LRE+ +CRDVDEC+ + C R C+NL G + C C G + G C D NEC
Sbjct: 2198 LREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECH 2257
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE-----------CDELPHP-- 284
+C NGRC NT GSFRC+C G+ + C D+ + C L
Sbjct: 2258 AQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSE 2317
Query: 285 --------CG--RDGNPSCTNT----NGGYE--CSCGAGWKLVGRRCVDRDECKELPYVC 328
CG R P C Y C G+G+ GR D DEC+ L ++C
Sbjct: 2318 AVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGR---DVDECRMLAHLC 2374
Query: 329 AGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECC 388
A GEC N G + C C AG+ D TA C+D DE C Q+ +P C
Sbjct: 2375 AHGECINSLGSFRCHCQAGYTPDATATTCLD------MDE-----CS-----QVPKP-CT 2417
Query: 389 CSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGS 448
G + CP E + G +DLDEC R C CVNT G+
Sbjct: 2418 FLCKNTKGSFLCSCPRGYLLE-----EDG----RTCKDLDECTSRQHNCQF-LCVNTVGA 2467
Query: 449 FRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQ-GPDQT 506
F C CP G+ +C D DEC+ P CG +G C NT G + C+C GFT
Sbjct: 2468 FTCRCPPGFTQHHQ--ACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHG 2525
Query: 507 CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-C 565
C DV+EC +G C C N G +RC+CP G+ + C D +EC P C A C
Sbjct: 2526 CEDVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASC 2584
Query: 566 ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
N +G + C CP G+ A C+D++EC + CS C NT G FLC C G
Sbjct: 2585 RNTLGGFRCVCPSGFDFDQAL----GGCQDVDECAGRRGPCSYS-CANTPGGFLCGCPQG 2639
Query: 626 F 626
+
Sbjct: 2640 Y 2640
Score = 356 bits (876), Expect = 2e-97
Identities = 213/603 (35%), Positives = 278/603 (46%), Gaps = 41/603 (6%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC LC G C + P G++C C+ G++ C+DVDEC+ G G C N
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFG--SCEN 1421
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENV 188
LPG F C C GY L C D++EC D C +G C NT GSY C C + L +
Sbjct: 1422 LPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481
Query: 189 CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC 248
VD + C T + C + G + C + R G C
Sbjct: 1482 VGCVDTRAGN---CFLETHDRGDSGISCSAEIGVGVTRASCCCSLG--RAWGNPCELCPM 1536
Query: 249 RNTVGSFRCECAPGYTLTADGRNC--RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
NT +R C G + D+DEC ELP C + G+ C NT G ++C C
Sbjct: 1537 ANTT-EYRTLCPGGEGFQPNRITVILEDIDECQELPGLC-QGGD--CVNTFGSFQCECPP 1592
Query: 307 GWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKEL 364
G+ L R C D DEC +C G C N G Y C CPA + C+D RK +
Sbjct: 1593 GYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSV 1652
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMRICQGGMGRPN 422
C+ + G C + R CCCS G AW R CE CP P S ++ +C G
Sbjct: 1653 CFRHYN-GTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILC-GNQAPGF 1710
Query: 423 LTQ-------DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
LT D+DEC P +C G C+N GSFRCECP G+ L+C D DEC
Sbjct: 1711 LTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSR 1770
Query: 476 PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRC 533
C N C N G Y C+C+ G+ P CV +EC E C+ C +T GS+ C
Sbjct: 1771 ESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMC 1830
Query: 534 TCPYGYAVAADGVHCRDIDECVQEPRVCPH-ACENVVGSYICKCPEGYRRTSAPQDSENA 592
C G+ +AD C DIDEC ++P C + C+N++GSY C C G+ T
Sbjct: 1831 LCHRGFQASADQTLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGFVVT-----HNGD 1883
Query: 593 CEDINECEE-QEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGR 651
C D +EC +C G C+NT GSF C C GFE + DG +C+D T C ++G
Sbjct: 1884 CVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVD--TNECLS--LAGT 1939
Query: 652 CEP 654
C P
Sbjct: 1940 CLP 1942
Score = 343 bits (842), Expect = 2e-93
Identities = 209/655 (31%), Positives = 294/655 (44%), Gaps = 59/655 (9%)
Query: 9 SCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPI 68
SC+ +GV T+ CCCS+G AWG PCE CP + + LC G N +T + I
Sbjct: 1505 SCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDI 1564
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC +P LC+ G C +T FQC C GY + +C D+DECS C G C N
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGTCYN 1623
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTI--GSYRCECKPGYTLRE 186
G + C CP Y + C D+ + R +G C+N + R C Y + +
Sbjct: 1624 TLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHY-NGTCQNELAFNVTRKMCCCSYNIGQ 1682
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
R + C P C N +L G +D++EC E +C NG
Sbjct: 1683 AWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTG-------KPLDIDECGEIPAICANG 1735
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
C N +GSFRCEC G+ + C DVDEC PC + N C N G Y C C
Sbjct: 1736 ICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQ--NADCINIPGSYRCKCTR 1793
Query: 307 GWKL-VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
G+KL G CV R+EC+E+P VC+ G+C + G Y+C C G++ +C+D
Sbjct: 1794 GYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMD------ 1847
Query: 366 YDEWEAGRCHRARPLQ-LARPECCCSEG----------------AAWGRYCERCPAPDSA 408
DE + C + C C G G+ C ++A
Sbjct: 1848 IDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTA 1907
Query: 409 -EFMRICQGGM---GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
F +CQ G D +EC C+ G C N +GSFRC CP G+ + D
Sbjct: 1908 GSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSD-- 1965
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
C+D DEC+ +P +C GTC+N+ G ++C C PGF + C + R S C
Sbjct: 1966 HCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG-----HRCFDTRQSF---C 2017
Query: 525 HNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEP-RVCPHACENVVGSYICKCPEGYRR 582
+ +C+ P + C + E +P +CP + ++ CP G+
Sbjct: 2018 FTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCP---QEGSAAFQELCPFGHGA 2074
Query: 583 TSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
P DS ED+NEC E +C+ GVC+NTDGSF C+C G+ G +C+D
Sbjct: 2075 VPGPDDSR---EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVD 2126
Score = 337 bits (828), Expect = 1e-91
Identities = 216/646 (33%), Positives = 295/646 (45%), Gaps = 65/646 (10%)
Query: 23 CCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGT 82
CC ++G AWG+PCE C PA G VT + ++EC+ P +C G
Sbjct: 834 CCATLGAAWGSPCERCEI--DPACARGFARMTG-----VTCDD--VNECESFPGVCPNGR 884
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDV--DEC--SWGRPPCRGMAQCVNLPGAFE---C 135
C +T F+C C G D + LC DV + C W C V LPG + C
Sbjct: 885 CVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECG-----VTLPGKYRMDVC 939
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDEC 195
C G + C D + +C G +G + G +DV+EC
Sbjct: 940 CCSIGAVWGVECEACPDPESLEFASLCPRG-----LGFASRDFLSGRPFY----KDVNEC 990
Query: 196 SRPRPVCRNGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRNGRCRNTVGS 254
+C +GTC N G++ C C GF +C D++ECR +C G C NT GS
Sbjct: 991 KVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGS 1050
Query: 255 FRCECAPGYTLTAD-GRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV-- 311
F CEC PGY +NC DVDEC P C R G +CTNT+G Y+C C G +L
Sbjct: 1051 FECECFPGYESGFMLMKNCMDVDECARDPLLC-RGG--TCTNTDGSYKCQCPPGHELTAK 1107
Query: 312 GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK--------- 362
G C D DEC +C G+C N G + C C AG++ CVD +
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCD 1167
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCS---EGAAWGRYCERCPAPDSAEFMR-ICQGG- 417
C + + RC + L C+ E R C++ + R +C G
Sbjct: 1168 VHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGF 1227
Query: 418 MGRPNLTQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
M P++ D+DEC + P +C+ G C NT GSF C C GY++ C D DEC +
Sbjct: 1228 MATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVG 1287
Query: 476 PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFR 532
C + +C N G + C+C PG+ G C D+DEC C+ R C N GS+R
Sbjct: 1288 GHNCDSHASCLNIPGSFSCRCLPGWV-GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYR 1346
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSEN 591
CTC G+A DG C D DEC + +C + C N G Y C+C G+ P +
Sbjct: 1347 CTCRQGFA--GDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFD----PTEDHR 1400
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
AC+D++EC Q +LC+ G C N G F C C+ G+E G +C D
Sbjct: 1401 ACQDVDEC-AQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTD 1445
Score = 329 bits (808), Expect = 3e-89
Identities = 239/714 (33%), Positives = 308/714 (43%), Gaps = 111/714 (15%)
Query: 21 YLCCCSVGHAWGAPCEACPPRGSPAHTAL------CGEKPGEYINPV---------TNET 65
Y C C++G+ GA + C A +L C PG Y T
Sbjct: 705 YRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEIC 764
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS-WGR---PPCR 121
K +DEC P C G C + + C C G D + C D + + W + C
Sbjct: 765 KDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE 822
Query: 122 GMAQ--------CVNLPGAF-----ECR----CPPGYRLTPSLDECEDVDECGD-QRICD 163
Q C L A+ C C G+ + C+DV+EC +C
Sbjct: 823 VNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVT-CDDVNECESFPGVCP 881
Query: 164 HGDCRNTIGSYRCECKPGYTLREN--VCRDV-----------DECSRPRP--------VC 202
+G C NT GS+RCEC G L + +C DV DEC P C
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCC 941
Query: 203 RNGT-----CENLPG------AYLCHCDDGFKA----GPNNDCVDVNECREGGMVCRNGR 247
G CE P A LC GF + DVNEC+ +C +G
Sbjct: 942 SIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT 1001
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
CRNTVGSF C CA G+ L A RNC D+DEC P CG+ +C NT G +EC C G
Sbjct: 1002 CRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG---TCVNTPGSFECECFPG 1058
Query: 308 WK---LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKE 363
++ ++ + C+D DEC P +C GG C N +G Y C+CP G C D +
Sbjct: 1059 YESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECS 1118
Query: 364 L---------CYDEWEAGRC--HRARPLQLARPECC-CSEGAAWGRYCE-RCPAPDSAEF 410
L C + A +C H R C +E C+ C + +
Sbjct: 1119 LSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYR 1178
Query: 411 MRICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
QG P+ D+DEC P VC G C N G RC C DG++ PD +CVD
Sbjct: 1179 CSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVD 1238
Query: 469 ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFR--CH 525
DEC L+P IC +G C NT+G + C C G+ T C DVDEC G +C C
Sbjct: 1239 VDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCL 1298
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECV-QEPRVCPHA-CENVVGSYICKCPEGYRRT 583
N GSF C C G+ DG C D+DECV QE R P C NV GSY C C +G+
Sbjct: 1299 NIPGSFSCRCLPGWV--GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGD 1356
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
CED +EC E DLC G C+N G + C+C+ GF+P+ED C D
Sbjct: 1357 GF------FCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 290 bits (711), Expect = 2e-77
Identities = 192/556 (34%), Positives = 250/556 (44%), Gaps = 83/556 (14%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC + C GTC + GF+C C G+E C D+DECS C +C N
Sbjct: 2128 DECSV-GHPCGQGTCTNVIGGFECACADGFE-PGLMMTCEDIDECSLNPLLCA--FRCHN 2183
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICD-HG-DCRNTIGSYRCECKPGYTLR 185
G++ C CP GY L C DVDEC D Q+ C G +C+N IG++ C C PG
Sbjct: 2184 TEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPL 2243
Query: 186 ENV---CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF------------KAGP---- 226
C D +EC +C NG C N G++ C CD+GF + GP
Sbjct: 2244 PGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAE 2303
Query: 227 -----------NNDCVDVNECREGGMVCRNGRCRNT----VGSFRCECAPGYTLTADGRN 271
+++ V EC GG RC ++R C G TA+GR
Sbjct: 2304 VLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGR- 2362
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK--LVGRRCVDRDECKELPYVCA 329
DVDEC L H C C N+ G + C C AG+ C+D DEC ++P C
Sbjct: 2363 --DVDECRMLAHLCAHG---ECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCT 2417
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C+N G ++C CP G+ ++ C D DE + R H + L C
Sbjct: 2418 F-LCKNTKGSFLCSCPRGYLLEEDGRTCKD------LDECTS-RQHNCQFL------CVN 2463
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGS 448
+ GA + RCP P + + C D DEC +P C G C NT GS
Sbjct: 2464 TVGA----FTCRCP-PGFTQHHQACF----------DNDECSAQPGPCGAHGHCHNTPGS 2508
Query: 449 FRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-C 507
FRCEC G+ L G C D +EC P C +G C N GGY C C GFTQ C
Sbjct: 2509 FRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQC 2566
Query: 508 VDVDECAEGRASC-TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
VD +ECA +C + C NT G FRC CP G+ C+D+DEC C ++C
Sbjct: 2567 VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYSCA 2626
Query: 567 NVVGSYICKCPEGYRR 582
N G ++C CP+GY R
Sbjct: 2627 NTPGGFLCGCPQGYFR 2642
Score = 290 bits (711), Expect = 2e-77
Identities = 195/525 (37%), Positives = 244/525 (46%), Gaps = 87/525 (16%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC--RGMAQ 125
IDEC + P LC CH+T + C C GY +CRDVDEC+ G+ C RGM +
Sbjct: 2167 IDECSLNPLLCA-FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGM-E 2224
Query: 126 CVNLPGAFECRCPPGYRLTPSLDE-CEDVDECGDQR-ICDHGDCRNTIGSYRCECKPGY- 182
C NL G F C CPPG R P E C D +EC Q +C +G C NT GS+RC+C G+
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 183 ---TLRE---------------NVCRDVDECS----RPRPVCRNGT-----CE--NLPG- 212
TL E +CR + S R C G CE LPG
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGT 2344
Query: 213 -AYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRN 271
AY C G +G + DV+ECR +C +G C N++GSFRC C GYT A
Sbjct: 2345 SAYRKLCPHG--SGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATT 2402
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCA 329
C D+DEC ++P PC C NT G + CSC G+ L GR C D DEC + C
Sbjct: 2403 CLDMDECSQVPKPC----TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQ 2458
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C N G + C CP G+ + + C+D E A+P C
Sbjct: 2459 F-LCVNTVGAFTCRCPPGFT----------QHHQACFDNDECS----------AQPGPCG 2497
Query: 390 SEGAAWGRYCERCPAPDSAEFMR---ICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTD 446
+ G +C P E + + G G +D++EC P C G C N
Sbjct: 2498 AHG-----HCHNTPGSFRCECHQGFTLVSSGHG----CEDVNECD-GPHRCQHG-CQNQL 2546
Query: 447 GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT 506
G +RC CP G+ CVD +ECAL P CG+ +C NT GG+ C C GF DQ
Sbjct: 2547 GGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDF--DQA 2604
Query: 507 ---CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC 548
C DVDECA R C++ C NT G F C CP GY A G HC
Sbjct: 2605 LGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG-HC 2648
Score = 287 bits (704), Expect = 1e-76
Identities = 241/778 (30%), Positives = 309/778 (39%), Gaps = 109/778 (14%)
Query: 122 GMAQCVNLPGAFECR--CPPGYRLTPSLDECED---VDECGDQRICDHG-DCRN--TIGS 173
G +QCV +P CR C G+ P+L C D CG R C N T
Sbjct: 77 GRSQCV-VP---ICRRACGEGFCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMNGGTCRG 132
Query: 174 YRCECKPGYTLRENVCRDVDECSRPRPVCRNG-------TCENLPGAYLCHCDDGFKAGP 226
C C+ GYT VC C R C NG C + G C+ ++ GP
Sbjct: 133 ASCLCQKGYT--GTVCGQ-PICDRG---CHNGGRCIGPNRCACVYGFMGPQCERDYRTGP 186
Query: 227 NNDCVDVNECREG--GMVCRNGRCRNTVG---SFRCECAP--------GYTLTADGRNCR 273
V C+ G+VC C TVG CE P G+ C+
Sbjct: 187 CFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQ 246
Query: 274 DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPY-VCAGGE 332
DVDEC +P C G SC N G + C C G +L D + V GG
Sbjct: 247 DVDECQAVPGLC--QGG-SCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGR 303
Query: 333 CRNFNGGYV----CECPAG--WRFDKTAAVCV----DERKELCYDEWEAGRCHRAR-PLQ 381
C G+ C C G W +C +E ++LC H P
Sbjct: 304 CAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGL 363
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
L R + +G L Q +D CR ++C+ GR
Sbjct: 364 LGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGR 423
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
C+ T S+RCEC GY G C+D DEC P C +G C N G Y C+C PGF
Sbjct: 424 CLPTPSSYRCECNVGYTQDVRG-ECIDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQA 480
Query: 502 GPD-QTCVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPR 559
P Q CVDVDEC C RC NT GSF+C C G+ ++ DG +C D +EC
Sbjct: 481 TPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 560 VCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFL 619
C N GS+ C C G+ AP + C DI+EC + +C G C NT+GSF
Sbjct: 541 CVNGVCLNEDGSFSCLCKPGF--LLAP--GGHYCMDIDEC-QTPGICVNGHCTNTEGSFR 595
Query: 620 CDCDAGFEPSEDGTDCIDRRT-GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXG 678
C C G DG C+D TCY ++ G C G
Sbjct: 596 CQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSC--------------------ARPFPG 635
Query: 679 HVTKAQCCC-TLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXX 737
VTK++CCC +G C+LCPA S LC++
Sbjct: 636 TVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSS----------------GLGITTD 679
Query: 738 XXXXLDVFADVDECAAIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ 793
+ D + CA G+C G +RCVC GY +G+ C DVDECA+ CD
Sbjct: 680 GRDINECALDPEVCA--NGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDN 737
Query: 794 -LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
C N+ GSY C C G+ +D C+DVDEC + +C N GSY C C G
Sbjct: 738 GWCQNSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPG 794
Score = 263 bits (644), Expect = 2e-69
Identities = 204/618 (33%), Positives = 258/618 (41%), Gaps = 70/618 (11%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGA-PC-EACPPRGSPAHTALCGEK-------PGEYINP 60
CAG + T+ CCC G W A P E CPPRGS LC ++ PG +
Sbjct: 304 CAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGL 363
Query: 61 VTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+ + + + P P H + G + T+ L + +D C C
Sbjct: 364 LGFGSNGMGP-PLGPARLNP---HGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLC 419
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
+C+ P ++ C C GY EC DVDEC C HGDC N G+Y C C P
Sbjct: 420 LN-GRCLPTPSSYRCECNVGY-TQDVRGECIDVDECTSSP-CHHGDCVNIPGTYHCRCYP 476
Query: 181 GY--TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECR 237
G+ T C DVDEC +C G C N G++ C C+ GF+ P+ +CVD NEC
Sbjct: 477 GFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECA 536
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTN 297
M C NG C N GSF C C PG+ L G C D+DEC + P C N CTNT
Sbjct: 537 TSTM-CVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDEC-QTPGIC---VNGHCTNTE 591
Query: 298 GGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGEC-RNFNGGYV---CECP-AGWRF 350
G + C C G + GR CVD G C R F G C C F
Sbjct: 592 GSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGF 651
Query: 351 DKTAAVC----VDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPD 406
+ +C E + LC R PE C + R RC
Sbjct: 652 GEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNL 711
Query: 407 SAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
E G G+ D+DEC + +C G C N+ GS+ C CP G+ D C
Sbjct: 712 GYE-----AGASGKD--CTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEIC 764
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDE--C----AEGR-- 517
D DEC P C +G C N G Y C+C PG P T C+D + C E R
Sbjct: 765 KDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE 822
Query: 518 -----ASCTFRCHNTAGSF------RC----TCPYGYAVAADGVHCRDIDECVQEPRVCP 562
AS C T G+ RC C G+A GV C D++EC P VCP
Sbjct: 823 VNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFA-RMTGVTCDDVNECESFPGVCP 881
Query: 563 HA-CENVVGSYICKCPEG 579
+ C N GS+ C+CPEG
Sbjct: 882 NGRCVNTAGSFRCECPEG 899
Score = 258 bits (633), Expect = 5e-68
Identities = 221/687 (32%), Positives = 281/687 (40%), Gaps = 129/687 (18%)
Query: 40 PRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYE 99
P GS A + PG + ID C LC G C TP+ ++C C+ GY
Sbjct: 382 PHGSDAR-GIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYT 440
Query: 100 HDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GD 158
D C DVDEC+ PC CVN+PG + CRC PG++ TP+ C DVDEC
Sbjct: 441 QDVRGE-CIDVDECT--SSPCH-HGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVS 496
Query: 159 QRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLC 216
+C G C NT GS++C C G+ L + C D +EC+ +C NG C N G++ C
Sbjct: 497 GGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECA-TSTMCVNGVCLNEDGSFSC 555
Query: 217 HCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV 275
C GF P C+D++EC+ G +C NG C NT GSFRC+C G + DGR C D
Sbjct: 556 LCKPGFLLAPGGHYCMDIDECQTPG-ICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDT 614
Query: 276 ---DEC--------DELPHP---------CGRD----GNPS--CTNTNGG-YECSCGAGW 308
C P P C G P C N ++ C +G
Sbjct: 615 HVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGL 674
Query: 309 KLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCY 366
+ GR D +EC P VCA G C N G Y C C G+ + C D
Sbjct: 675 GITTDGR---DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTD------V 725
Query: 367 DEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM---GRPNL 423
DE C A C G +C+ P S C G +
Sbjct: 726 DE-----C--------ALNSLLCDNG-----WCQNSPGSYSCS----CPPGFHFWQDTEI 763
Query: 424 TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA---------DECAL 474
+D+DEC P CV G C N GS+ C+C G L P G C+D+ E
Sbjct: 764 CKDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRC 821
Query: 475 DPRICG---NGTCSNTRG---GYECQ-------CSPGFTQGPDQTCVDVDECAEGRASC- 520
+ + G C T G G C+ C+ GF + TC DV+EC C
Sbjct: 822 EVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCP 881
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRDI-----------DEC-VQEP-----RVCPH 563
RC NTAGSFRC CP G + A G C D+ DEC V P VC
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCC 941
Query: 564 ACENVVG------------SYICKCPEGYRRTSAP-QDSENACEDINECEEQEDLCSGGV 610
+ V G + CP G S +D+NEC+ LC+ G
Sbjct: 942 SIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT 1001
Query: 611 CINTDGSFLCDCDAGFEPSEDGTDCID 637
C NT GSF C C GF +C D
Sbjct: 1002 CRNTVGSFHCACAGGFALDAQERNCTD 1028
Score = 237 bits (580), Expect = 1e-61
Identities = 170/513 (33%), Positives = 219/513 (42%), Gaps = 93/513 (18%)
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGR 287
N +D+ CR +C NGRC T S+RCEC GYT G C DVDEC P G
Sbjct: 406 NQTIDI--CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDECTSSPCHHG- 461
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECP 345
C N G Y C C G++ R CVD DEC +C G C N G + C C
Sbjct: 462 ----DCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCN 517
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
AG+ CVD + C + + C +E ++ C+ P
Sbjct: 518 AGFELSPDGKNCVDHNE-----------CATST---MCVNGVCLNEDGSFSCLCK--PG- 560
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
F+ + GG + D+DEC+ P +CV G C NT+GSFRC+C G + DG
Sbjct: 561 ----FL-LAPGG----HYCMDIDECQT-PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRV 610
Query: 466 CVDA---DEC--ALDPRICGN---GT-------CSNTRGGY--ECQCSPGFTQGPDQTCV 508
CVD C A++ C GT C+N G+ CQ P Q
Sbjct: 611 CVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALC 670
Query: 509 -----------DVDECAEGRASCTFR-CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
D++ECA C C N GS+RC C GY A G C D+DEC
Sbjct: 671 SSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECAL 730
Query: 557 EPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTD 615
+C + C+N GSY C CP G+ QD+E C+D++EC C GVC N
Sbjct: 731 NSLLCDNGWCQNSPGSYSCSCPPGFHFW---QDTE-ICKDVDECLSSP--CVSGVCRNLA 784
Query: 616 GSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXX 675
GS+ C C G GT C+D GTC+ + RCE
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE--------------------VN 824
Query: 676 XXGHVTKAQCCCTLGAAWGSECELCPAPGSPAR 708
G +++CC TLGAAWGS CE C + AR
Sbjct: 825 LQGASLRSECCATLGAAWGSPCERCEIDPACAR 857
Score = 212 bits (517), Expect = 5e-54
Identities = 157/523 (30%), Positives = 203/523 (38%), Gaps = 74/523 (14%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAW---GAPC----------EACPPRGSPAH----TALCGE 52
CA + YLC C G+ GA C + C RG T C
Sbjct: 2177 CAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVC 2236
Query: 53 KPGEYINPVTNETKPID-ECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVD 111
PG P + E D EC P LC G C +T F+C CD G++ T C D+
Sbjct: 2237 PPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIR 2296
Query: 112 E----CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDC 167
+ + CR ++ EC C G P + C +++C HG
Sbjct: 2297 QGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGS- 2355
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN 227
GYT RDVDEC +C +G C N G++ CHC G+
Sbjct: 2356 -------------GYTAEG---RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDAT 2399
Query: 228 -NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C+D++EC + C C+NT GSF C C GY L DGR C+D+DEC H C
Sbjct: 2400 ATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNC- 2457
Query: 287 RDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVC-AGGECRNFNGGYVCECP 345
C NT G + C C G+ + C D DEC P C A G C N G + CEC
Sbjct: 2458 ---QFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECH 2514
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
G+ + C D + C RC QL C C +G +C
Sbjct: 2515 QGFTLVSSGHGCEDVNE--CDGPH---RCQHGCQNQLGGYRCSCPQGFTQHSQWAQCV-- 2567
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
D +EC + P C C NT G FRC CP G+
Sbjct: 2568 --------------------DENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGG 2607
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV 508
C D DECA C +C+NT GG+ C C G+ + CV
Sbjct: 2608 CQDVDECAGRRGPCSY-SCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 180 bits (438), Expect = 2e-44
Identities = 99/242 (40%), Positives = 122/242 (50%), Gaps = 22/242 (9%)
Query: 414 CQGGMGRPNLTQ----DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
CQ G P+ T D+DEC P C C NT GSF C CP GY+L DG +C D
Sbjct: 2390 CQAGY-TPDATATTCLDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDL 2447
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNT 527
DEC C C NT G + C+C PGFTQ Q C D DEC+ C CHNT
Sbjct: 2448 DECTSRQHNC-QFLCVNTVGAFTCRCPPGFTQH-HQACFDNDECSAQPGPCGAHGHCHNT 2505
Query: 528 AGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQ 587
GSFRC C G+ + + G C D++EC P C H C+N +G Y C CP+G+ + S Q
Sbjct: 2506 PGSFRCECHQGFTLVSSGHGCEDVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHS--Q 2562
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE------PSEDGTDCIDRRTG 641
++ C D NEC C C NT G F C C +GF+ +D +C RR G
Sbjct: 2563 WAQ--CVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRR-G 2619
Query: 642 TC 643
C
Sbjct: 2620 PC 2621
Score = 98.7 bits (235), Expect = 8e-20
Identities = 116/418 (27%), Positives = 158/418 (37%), Gaps = 56/418 (13%)
Query: 250 NTVGS-FRCECAPGYTLTADGRNCRDVDECDELPHPCGRD--GNPS-CTNTNGGYECSCG 305
N GS F C PG+ T GR+ V C CG P+ CT +G SCG
Sbjct: 58 NVCGSRFHAYCCPGWR-TFPGRSQCVVPICRRA---CGEGFCSQPNLCTCADGTLAPSCG 113
Query: 306 AG-WKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCE--CPAGWR-FDKTAAVCV--- 358
C++ C+ +C G G +C+ C G R CV
Sbjct: 114 VSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCACVYGF 173
Query: 359 -------DERKELCYDEWEAGRC-HRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
D R C+ + C H+ L + CC + G AWG CE CPA
Sbjct: 174 MGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHP-- 231
Query: 411 MRICQGGMGRPNL----TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
C+ G PN+ QD+DEC+ P +C GG CVN GSF C CP G+ L+ +C
Sbjct: 232 ---CRRGF-IPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAAC 287
Query: 467 VDADECALDPRICGNGTCSNTRGGY----ECQCSPG--FTQGPDQTCVDVDECAEGRASC 520
D A + G G C+ G+ +C C G + GP E + C
Sbjct: 288 EDYRAGACFSVLFG-GRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLC 346
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPE-G 579
R G P G G + + R+ PH GS P G
Sbjct: 347 AQRLPLLPGH-----P-GLFPGLLGFGSNGMGPPLGPARLNPH------GSDARGIPSLG 394
Query: 580 YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
++ + N DI C +LC G C+ T S+ C+C+ G+ G +CID
Sbjct: 395 PGNSNIGTATLNQTIDI--CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRG-ECID 449
Score = 98.3 bits (234), Expect = 1e-19
Identities = 46/113 (40%), Positives = 57/113 (50%), Gaps = 9/113 (7%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL--CHNT 798
D+DEC + C G F C C PG+ + C D DEC+ +P PC CHNT
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNT 2505
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
GS+ C C G+ L G C DV+EC+ H CQ C N G Y CSC G+
Sbjct: 2506 PGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHGCQNQLGGYRCSCPQGF 2557
Score = 97.9 bits (233), Expect = 1e-19
Identities = 51/124 (41%), Positives = 61/124 (49%), Gaps = 11/124 (8%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHN 797
D DECA LC APG +RC C G+ P + C DVDECA C N
Sbjct: 1362 DRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCEN 1421
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRG 855
G + C+C GYELD G NC D++EC + +C NT GSY CSC +E G
Sbjct: 1422 LPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481
Query: 856 DACV 859
CV
Sbjct: 1482 VGCV 1485
Score = 89.0 bits (211), Expect = 6e-17
Identities = 39/103 (37%), Positives = 54/103 (52%), Gaps = 4/103 (3%)
Query: 761 GRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDEDGA 817
G +RC C G+ + C D +ECA+ PP C C NT G + C+C +G++ D+
Sbjct: 2547 GGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALG 2606
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
C+DVDEC C C+NT G + C C GY + G CV
Sbjct: 2607 GCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 84.2 bits (199), Expect = 2e-15
Identities = 49/125 (39%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQ--LC 795
DVDEC P +C G F C C GY R C+DVDEC V CD C
Sbjct: 1238 DVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASC 1297
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEK 853
N GS+ C C G+ DG C D+DEC H C C N GSY C+C G+
Sbjct: 1298 LNIPGSFSCRCLPGWV--GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355
Query: 854 RGDAC 858
G C
Sbjct: 1356 DGFFC 1360
Score = 80.6 bits (190), Expect = 2e-14
Identities = 44/117 (37%), Positives = 53/117 (45%), Gaps = 12/117 (10%)
Query: 747 DVDECAAIPGLCA--------PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCH 796
D DEC+A PG C PG FRC C G+ +G C DV+EC P C C
Sbjct: 2485 DNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHGCQ 2543
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYE 852
N G Y C C G+ A C D +EC TC C NT G + C C G++
Sbjct: 2544 NQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFD 2600
Score = 73.3 bits (172), Expect = 3e-12
Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 7/95 (7%)
Query: 15 GVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIM 74
G+ TK LCC +VG AWG PCE CP + P + G N T + +DEC +
Sbjct: 202 GLVCTKALCCATVGRAWGLPCELCPAQPHPC-------RRGFIPNIHTGACQDVDECQAV 254
Query: 75 PQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
P LC+ G+C + F C C G+ ++S C D
Sbjct: 255 PGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 70.9 bits (166), Expect = 2e-11
Identities = 45/120 (37%), Positives = 58/120 (48%), Gaps = 12/120 (10%)
Query: 751 CAAIPGLCAPGRFRCVCG---PGYRP---AGEVCADVDECAVRPPPC-DQLCHNTDGSYD 803
C A P +P ++ +CG PG+ G+ D+DEC P C + +C N GS+
Sbjct: 1688 CEACPTPISPD-YQILCGNQAPGFLTDIHTGKPL-DIDECGEIPAICANGICINQIGSFR 1745
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE-KRGDACVG 860
C C G+ + C DVDEC CQQ C N GSY C C GY+ G ACVG
Sbjct: 1746 CECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVG 1805
Score = 50.4 bits (115), Expect = 3e-05
Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 32/149 (21%)
Query: 743 DVFADVDECAAIP---GLCA--PGRFRCVCGPGYR--PAGEVCADVDE--C--AVRPPPC 791
++ DVDEC + P G+C G + C CGPG R P+G C D + C ++ C
Sbjct: 762 EICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRC 821
Query: 792 DQLCHNTDGSYDCLCRTGY---------ELDE---------DGANCRDVDECERDTHTCQ 833
+ +C G E+D G C DV+ECE C
Sbjct: 822 EVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCP 881
Query: 834 Q-ICSNTEGSYECSCEDG--YEKRGDACV 859
C NT GS+ C C +G + G CV
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCV 910
Score = 48.0 bits (109), Expect = 1e-04
Identities = 57/195 (29%), Positives = 74/195 (37%), Gaps = 34/195 (17%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
GTC G C C GY T +C C G C +C+ G C C G
Sbjct: 128 GTCR----GASCLCQKGY----TGTVCGQ-PICDRG---CHNGGRCI---GPNRCACVYG 172
Query: 141 YRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRP 200
+ + P +CE D R G C +G C+ + L VC C+
Sbjct: 173 F-MGP---QCER-----DYRT---GPCFGQVGPEGCQ----HQLTGLVCTKALCCATVGR 216
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCEC 259
CE P A C GF + C DV+EC+ +C+ G C N VGSF C C
Sbjct: 217 AW-GLPCELCP-AQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRC 274
Query: 260 APGYTLTADGRNCRD 274
G+ L+ C D
Sbjct: 275 PVGHRLSDSSAACED 289
Score = 38.7 bits (86), Expect = 0.087
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGY 851
CR G+ + C+DVDEC+ CQ C N GS+ C C G+
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGH 278
>AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 1 protein.
Length = 2809
Score = 728 bits (1799), Expect = 0.0
Identities = 355/869 (40%), Positives = 460/869 (52%), Gaps = 64/869 (7%)
Query: 9 SCAGAVGVPQTKYLCCCS--VGHAWGAPCEACPPRGSPAHTALCGEK-PGEYINPVTNET 65
+C + T+ +CCCS +G AW PCEACP SP + LCG + PG + T +
Sbjct: 1660 TCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKP 1719
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ 125
IDEC +P +C G C + F+C C G+ +++ C DVDEC PC+ A
Sbjct: 1720 LDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCECKPGY-- 182
C+N+PG++ C+C GY+L+P C +EC + +C HGDC +T GSY C C G+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPG-GACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQA 1838
Query: 183 TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE-GGM 241
+ + +C D+DEC R +P C NGTC+N+ G+Y C C GF N DCVD +EC G
Sbjct: 1839 SADQTLCMDIDECDR-QP-CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 242 VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
VCR G C NT GSF C C G+ LTADG+NC D +EC L C G +C N G +
Sbjct: 1897 VCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTC-LPG--TCQNLEGSFR 1953
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER 361
C C G+++ C+D DEC E P +C G C N G + C CP G+ C D R
Sbjct: 1954 CICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTR 2013
Query: 362 KELCYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMRICQGGMG 419
+ C+ +EAG+C + + CCCS+ G WG CE CP SA F +C G G
Sbjct: 2014 QSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHG 2073
Query: 420 R----PNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
+ +D++EC P VC G CVNTDGSFRCECP GY L G++CVD DEC++
Sbjct: 2074 AVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG 2133
Query: 476 PRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
CG GTC+N GG+EC C+ GF G TC D+DEC+ C FRCHNT GS+ CTC
Sbjct: 2134 -HPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTC 2192
Query: 536 PYGYAVAADGVHCRDIDECVQEPRVCPHA----CENVVGSYICKCPEGYRRTSAPQDSEN 591
P GY + DG CRD+DEC + C HA C+N++G++ C CP G R P E
Sbjct: 2193 PAGYTLREDGAMCRDVDECADGQQDC-HARGMECKNLIGTFACVCPPGMR--PLPGSGE- 2248
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGR 651
C D NEC Q DLC G C+NT GSF CDCD GF+PS T+C D R G C+ ++
Sbjct: 2249 GCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTM 2308
Query: 652 CEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDL 711
C VT+A+CCC G WG CELCP PG+ A L
Sbjct: 2309 CR------------------SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKL 2350
Query: 712 CTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCAPGRFRCVCGPGY 771
C + A + CA + + G FRC C GY
Sbjct: 2351 CP--------------HGSGYTAEGRDVDECRMLAHL--CAHGECINSLGSFRCHCQAGY 2394
Query: 772 RP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDT 829
P C D+DEC+ P PC LC NT GS+ C C GY L+EDG C+D+DEC
Sbjct: 2395 TPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQ 2454
Query: 830 HTCQQICSNTEGSYECSCEDGYEKRGDAC 858
H CQ +C NT G++ C C G+ + AC
Sbjct: 2455 HNCQFLCVNTVGAFTCRCPPGFTQHHQAC 2483
Score = 458 bits (1129), Expect = e-128
Identities = 268/748 (35%), Positives = 343/748 (45%), Gaps = 83/748 (11%)
Query: 151 EDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTLR-ENVCRDVDECSRPRPVCRNGTCE 208
+ +D C +C +G C T SYRCEC GYT C DVDEC+ C +G C
Sbjct: 407 QTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSP--CHHGDCV 464
Query: 209 NLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTA 267
N+PG Y C C GF+A P CVDV+EC G +C GRC NT GSF+C C G+ L+
Sbjct: 465 NIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSP 524
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELP 325
DG+NC D +EC C N C N +G + C C G+ L G C+D DEC + P
Sbjct: 525 DGKNCVDHNEC-ATSTMCV---NGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDEC-QTP 579
Query: 326 YVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER-KELCYDEWEAGRCHRARPLQLAR 384
+C G C N G + C+C G VCVD + CY E G C R P + +
Sbjct: 580 GICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTK 639
Query: 385 PECCCSE-GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCV 443
ECCC+ +G C+ CPA +SAEF +C G+G +D++EC + P+VC G C
Sbjct: 640 SECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCE 699
Query: 444 NTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
N GS+RC C GY G C D DECAL+ +C NG C N+ G Y C C PGF
Sbjct: 700 NLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQ 759
Query: 504 D-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP 562
D + C DVDEC + C N AGS+ C C G + G C D + ++
Sbjct: 760 DTEICKDVDECLSS-PCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQE 818
Query: 563 HACE-NVVGSYI---CKCPEGYRRTSAPQDSE--------------NACEDINECEEQED 604
CE N+ G+ + C G S + E C+D+NECE
Sbjct: 819 SRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPG 878
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXX 664
+C G C+NT GSF C+C G G C+D R C+ C
Sbjct: 879 VCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDEC------------ 926
Query: 665 XXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXX 724
G CCC++GA WG ECE CP P S LC
Sbjct: 927 --------GVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCP----------- 967
Query: 725 XXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLC-------APGRFRCVCGPGYRPAGEV 777
+ DV+EC PGLC G F C C G+ +
Sbjct: 968 ----RGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQE 1023
Query: 778 --CADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD-EDGANCRDVDECERDTHTCQ 833
C D+DEC + P C Q C NT GS++C C GYE NC DVDEC RD C+
Sbjct: 1024 RNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCR 1083
Query: 834 -QICSNTEGSYECSCEDGYE--KRGDAC 858
C+NT+GSY+C C G+E +G AC
Sbjct: 1084 GGTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Score = 442 bits (1090), Expect = e-123
Identities = 286/830 (34%), Positives = 359/830 (43%), Gaps = 101/830 (12%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+DEC P LC+ GTC +T ++C C G+E C D+DECS C QCV
Sbjct: 1072 VDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH-GQCV 1130
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
N+ GAF+C C G++ TP C D++EC Q C NT GSYRC C GY+L +
Sbjct: 1131 NVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPD 1190
Query: 188 --VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCR 244
C DVDEC VC G C N+PG + C C DGF A P+ CVDV+EC +C
Sbjct: 1191 GRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICL 1250
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
+G C NT GSF C C GY + C DVDEC+ H C D + SC N G + C C
Sbjct: 1251 HGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNC--DSHASCLNIPGSFSCRC 1308
Query: 305 GAGWKLVGRRCVDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
GW G C D DEC + C+ G+C N G Y C C G+ D DE E
Sbjct: 1309 LPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAE 1368
Query: 364 --------LCYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMR- 412
C + RC C + A G C + R
Sbjct: 1369 NVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRC 1428
Query: 413 ICQGGM----GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
IC GG G N T D++EC P C+ G C+NT GS+ C CP + L P G+ CVD
Sbjct: 1429 ICNGGYELDRGGGNCT-DINEC-ADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVD 1486
Query: 469 --ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRA---SCTFR 523
A C L+ G+ G C G C C+ GRA C
Sbjct: 1487 TRAGNCFLETHDRGDS-------GISCSAEIGVGVTRASCC-----CSLGRAWGNPCELC 1534
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHC--RDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
+R CP G + + DIDEC + P +C C N GS+ C+CP GY
Sbjct: 1535 PMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGY 1594
Query: 581 RRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRT 640
+ + CEDI+EC +C G C NT G++ C C A + G +C+D R
Sbjct: 1595 HLS----EHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRK 1650
Query: 641 GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCT--LGAAWGSECE 698
C+R +G C+ E +VT+ CCC+ +G AW CE
Sbjct: 1651 SVCFRH-YNGTCQNELAF--------------------NVTRKMCCCSYNIGQAWNRPCE 1689
Query: 699 LCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLC 758
CP P SP LC N P D+DEC IP +C
Sbjct: 1690 ACPTPISPDYQILCG--NQAPGFLTDIHTGKP---------------LDIDECGEIPAIC 1732
Query: 759 AP-------GRFRCVCGPG--YRPAGEVCADVDECAVRPPPCDQL--CHNTDGSYDCLCR 807
A G FRC C G Y C DVDEC R PC Q C N GSY C C
Sbjct: 1733 ANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCT 1792
Query: 808 TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
GY+L GA C +EC + C C +TEGSY C C G++ D
Sbjct: 1793 RGYKLSPGGA-CVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASAD 1841
Score = 430 bits (1060), Expect = e-120
Identities = 232/592 (39%), Positives = 291/592 (49%), Gaps = 47/592 (7%)
Query: 1 MEWNEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
+ W+E++ C + +CCCS+G WG CEACP S +LC G
Sbjct: 919 LRWDEDE--CGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRD 976
Query: 61 VTNET---KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGR 117
+ K ++EC + P LC GTC +T F C C G+ D C D+DEC
Sbjct: 977 FLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISP 1036
Query: 118 PPCRGMAQCVNLPGAFECRCPPGYRLTPSL-DECEDVDECG-DQRICDHGDCRNTIGSYR 175
C G CVN PG+FEC C PGY L C DVDEC D +C G C NT GSY+
Sbjct: 1037 DLC-GQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYK 1095
Query: 176 CECKPGY--TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVD 232
C+C PG+ T + C D+DECS +C +G C N+ GA+ C C GF++ P+ CVD
Sbjct: 1096 CQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVD 1155
Query: 233 VNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
+NECR C + C NT GS+RC C GY+L DGR C DVDEC+E P C +
Sbjct: 1156 INECRVQNGGC-DVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQG---H 1211
Query: 293 CTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRF 350
CTN GG+ C C G+ R CVD DEC P++C G+C N G +VC C G+
Sbjct: 1212 CTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMV 1271
Query: 351 DKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
K A C D DE E G H C A+ C P S
Sbjct: 1272 RKGATGCSD------VDECEVGG-HN------------CDSHAS----CLNIPGSFSC-- 1306
Query: 411 MRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
R G +G DLDEC + C G C+N GS+RC C G+ A DG C D
Sbjct: 1307 -RCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCEDR 1363
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTA 528
DECA + +C NG C N GGY C+C GF D + C DVDECA+G C N
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLP 1423
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGY 580
G FRC C GY + G +C DI+EC C N GSY+C CP+ +
Sbjct: 1424 GMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDF 1475
Score = 409 bits (1007), Expect = e-113
Identities = 300/917 (32%), Positives = 373/917 (40%), Gaps = 98/917 (10%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPID 69
C VG Q C V +PC P T C PG P +D
Sbjct: 433 CECNVGYTQDVRGECIDVDECTSSPCHHGDCVNIPG-TYHCRCYPGFQATPTRQACVDVD 491
Query: 70 ECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
EC + LC G C +T FQC C+ G+E C D +EC+ G+ C+N
Sbjct: 492 ECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGV--CLNE 549
Query: 130 PGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN-- 187
G+F C C PG+ L P C D+DEC IC +G C NT GS+RC+C G + +
Sbjct: 550 DGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGR 609
Query: 188 VCRDVD------------ECSRPRP--VCRNGTCENLPG------AYLCHCDDG--FKA- 224
VC D C+RP P V ++ C P LC + F+A
Sbjct: 610 VCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQAL 669
Query: 225 -----GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECD 279
G D D+NEC VC NG C N GS+RC C GY A G++C DVDEC
Sbjct: 670 CSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECA 729
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFN 337
C N C N+ G Y CSC G+ C D DEC P C G CRN
Sbjct: 730 LNSLLCD---NGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLA 784
Query: 338 GGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGR 397
G Y C+C G R D + C+D K C+ + + RC R ECC + GAAWG
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGS 844
Query: 398 YCERCPAPDSAEFMRICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPD 455
CERC E C G R D++EC P VC GRCVNT GSFRCECP+
Sbjct: 845 PCERC------EIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPE 898
Query: 456 GYVLAPDGLSCVDA--DECAL--DPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDV 510
G +L G CVD + C L D CG R C CS G G + + C D
Sbjct: 899 GLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDV-CCCSIGAVWGVECEACPD- 956
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH-ACENVV 569
E E + C + F P+ +D++EC P +C H C N V
Sbjct: 957 PESLEFASLCPRGLGFASRDFLSGRPF----------YKDVNECKVFPGLCTHGTCRNTV 1006
Query: 570 GSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP- 628
GS+ C C G+ A E C DI+EC DLC G C+NT GSF C+C G+E
Sbjct: 1007 GSFHCACAGGF----ALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESG 1062
Query: 629 ----------SEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXG 678
E D + R GTC + S +C+ G
Sbjct: 1063 FMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDG 1122
Query: 679 HVTKAQCCCTLGAAWGS-ECELCPAPGSPARLDL--CTAVNLTPXXXXXXXXXXXXXXXX 735
QC +GA S P +D+ C N
Sbjct: 1123 LCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCG 1182
Query: 736 XXXXXXLD--VFADVDECAAIPGLC-------APGRFRCVCGPGY--RPAGEVCADVDEC 784
D ADVDEC P +C PG RC+C G+ P C DVDEC
Sbjct: 1183 QGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDEC 1242
Query: 785 AVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEG 841
+ P C C NT GS+ C C+ GY + + C DVDECE H C C N G
Sbjct: 1243 DLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPG 1302
Query: 842 SYECSCEDGYEKRGDAC 858
S+ C C G+ G C
Sbjct: 1303 SFSCRCLPGWVGDGFEC 1319
Score = 405 bits (996), Expect = e-112
Identities = 224/611 (36%), Positives = 293/611 (47%), Gaps = 53/611 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDE--------------- 112
IDEC P LC GTC ++P FQC C G+ + H C D +
Sbjct: 1970 IDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVP 2029
Query: 113 ---------CSWGRPPCRGMAQ-CVNLP----GAFECRCPPGYRLTPSLDEC-EDVDECG 157
C + P G C P AF+ CP G+ P D+ EDV+EC
Sbjct: 2030 KAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECA 2089
Query: 158 DQR-ICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAY 214
+ +C +G C NT GS+RCEC GY+L C D DECS P C GTC N+ G +
Sbjct: 2090 ENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP-CGQGTCTNVIGGF 2148
Query: 215 LCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRD 274
C C DGF+ G C D++EC ++C RC NT GS+ C C GYTL DG CRD
Sbjct: 2149 ECACADGFEPGLMMTCEDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Query: 275 VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV---GRRCVDRDECKELPYVCAGG 331
VDEC + C G C N G + C C G + + G C D +EC P +C G
Sbjct: 2208 VDECADGQQDCHARGM-ECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNG 2266
Query: 332 ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLA--RPECCC 389
C N G + C+C G++ T C D R+ C+ E C A R ECCC
Sbjct: 2267 RCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCC 2326
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
G WG CE CP P ++ + ++C G G +D+DECR+ +C G C+N+ GSF
Sbjct: 2327 GGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSF 2386
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCV 508
RC C GY +C+D DEC+ P+ C C NT+G + C C G+ D +TC
Sbjct: 2387 RCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCK 2445
Query: 509 DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC-PHA-CE 566
D+DEC + +C F C NT G+F C CP G+ C D DEC +P C H C
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQA--CFDNDECSAQPGPCGAHGHCH 2503
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
N GS+ C+C +G+ S S + CED+NEC+ C G C N G + C C GF
Sbjct: 2504 NTPGSFRCECHQGFTLVS----SGHGCEDVNECDGPH-RCQHG-CQNQLGGYRCSCPQGF 2557
Query: 627 EPSEDGTDCID 637
C+D
Sbjct: 2558 TQHSQWAQCVD 2568
Score = 395 bits (972), Expect = e-109
Identities = 287/876 (32%), Positives = 377/876 (43%), Gaps = 134/876 (15%)
Query: 21 YLCCCSVGHAW---GAPCEACPPRGSPAH--TALCGEKPGEYIN--PVTNETKP--IDEC 71
+ C C+ G+ G C P + +C PG Y+ P E P +
Sbjct: 1426 FRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCV 1485
Query: 72 DIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG 131
D C T +G C + G S C + +WG P C + N
Sbjct: 1486 DTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCC-SLGR-AWGNP-CE-LCPMANTT- 1540
Query: 132 AFECRCPPGYRLTPSLDEC--EDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTLREN- 187
+ CP G P+ ED+DEC + +C GDC NT GS++CEC PGY L E+
Sbjct: 1541 EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHT 1600
Query: 188 -VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF-KAGPNNDCVDVNECREGGMVC-- 243
+C D+DECS +C GTC N G Y C C + + N+C+D+ + VC
Sbjct: 1601 RICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKS-----VCFR 1655
Query: 244 -RNGRCRNTVGS--FRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGY 300
NG C+N + R C Y + C+ P P D C N G+
Sbjct: 1656 HYNGTCQNELAFNVTRKMCCCSYNIGQAWNR-----PCEACPTPISPDYQILCGNQAPGF 1710
Query: 301 ECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
G L D DEC E+P +CA G C N G + CECPAG+ ++ C D
Sbjct: 1711 LTDIHTGKPL------DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACED- 1763
Query: 361 RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG--M 418
DE + R P Q +C G+ RC ++ GG +
Sbjct: 1764 -----VDECGS----RESPCQ-QNADCINIPGSY------RCKCTRG---YKLSPGGACV 1804
Query: 419 GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRI 478
GR +ECR P+VC G C++T+GS+ C C G+ + D C+D DEC P
Sbjct: 1805 GR-------NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQP-- 1855
Query: 479 CGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAE--GRASCTF-RCHNTAGSFRCTC 535
CGNGTC N G Y C C PGF + CVD DEC G+ C F C NTAGSF C C
Sbjct: 1856 CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQV-CRFGHCLNTAGSFHCLC 1914
Query: 536 PYGYAVAADGVHCRDIDECVQEPRVC-PHACENVVGSYICKCPEGYRRTSAPQDSENACE 594
G+ + ADG +C D +EC+ C P C+N+ GS+ C CP G+ Q + C
Sbjct: 1915 QDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGF------QVQSDHCI 1968
Query: 595 DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEP 654
DI+EC E+ +LC G C N+ GSF C C GF S++G C D R C+ +G+C
Sbjct: 1969 DIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSV 2028
Query: 655 EXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTL--GAAWGSECELCPAPGSPARLDLC 712
+ TK +CCC+ G WG CELCP GS A +LC
Sbjct: 2029 PKAF--------------------NTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELC 2068
Query: 713 TAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCA-------PGRFRC 765
P D DV+ECA PG+C G FRC
Sbjct: 2069 ------PFGHGAVPGPD-------------DSREDVNECAENPGVCTNGVCVNTDGSFRC 2109
Query: 766 VCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
C GY G C D DEC+V P C N G ++C C G+E C D+D
Sbjct: 2110 ECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLM-MTCEDID 2168
Query: 824 ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 859
EC + C C NTEGSY C+C GY R D +
Sbjct: 2169 ECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAM 2204
Score = 380 bits (935), Expect = e-104
Identities = 219/596 (36%), Positives = 284/596 (47%), Gaps = 43/596 (7%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
CG+ G + P +DEC+ P++C G C + P G +C C G+ C D
Sbjct: 1181 CGQ--GYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVD 1238
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC--GDQRICDHGDC 167
VDEC C C N G+F C C GY + C DVDEC G H C
Sbjct: 1239 VDECDLNPHICLH-GDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASC 1297
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGP 226
N GS+ C C PG+ C D+DEC C G C N+PG+Y C C GF AG
Sbjct: 1298 LNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF-AGD 1356
Query: 227 NNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C D +EC E +C NG+C N G +RCEC G+ T D R C+DVDEC + + C
Sbjct: 1357 GFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ-GNLCA 1415
Query: 287 RDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
SC N G + C C G++L G C D +EC + P C G C N G Y+C C
Sbjct: 1416 FG---SCENLPGMFRCICNGGYELDRGGGNCTDINECAD-PVNCINGVCINTPGSYLCSC 1471
Query: 345 PAGWRFDKTAAVCVDERKELCY----DEWEAG-RCHRARPLQLARPECCCSEGAAWGRYC 399
P + + + CVD R C+ D ++G C + + R CCCS G AWG C
Sbjct: 1472 PQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPC 1531
Query: 400 ERCPAPDSAEFMRICQGGMG-RPN----LTQDLDECRVRPDVCVGGRCVNTDGSFRCECP 454
E CP ++ E+ +C GG G +PN + +D+DEC+ P +C GG CVNT GSF+CECP
Sbjct: 1532 ELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECP 1591
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ-GPDQTCVDVDEC 513
GY L+ C D DEC+ ICG GTC NT G Y C C + Q C+D+
Sbjct: 1592 PGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDM--- 1648
Query: 514 AEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVG-S 571
R S FR +N C + V C +I + P C AC +
Sbjct: 1649 ---RKSVCFRHYNGT----CQNELAFNVTRKMCCCSYNIGQAWNRP--C-EACPTPISPD 1698
Query: 572 YICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
Y C G + D DI+EC E +C+ G+CIN GSF C+C AGF
Sbjct: 1699 YQILC--GNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGF 1752
Score = 372 bits (914), Expect = e-102
Identities = 242/661 (36%), Positives = 302/661 (45%), Gaps = 88/661 (13%)
Query: 11 AGAVGVPQ----TKYLCCCSV--GHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNE 64
AG VP+ TK CCCS G WG PCE CP GS A LC G P +
Sbjct: 2023 AGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGP-DDS 2081
Query: 65 TKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+ ++EC P +C G C +T F+C C GY D T C D DECS G P C G
Sbjct: 2082 REDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP-C-GQG 2139
Query: 125 QCVNLPGAFECRCPPGYRLTPSLD-ECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYT 183
C N+ G FEC C G+ P L CED+DEC + C NT GSY C C GYT
Sbjct: 2140 TCTNVIGGFECACADGFE--PGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYT 2197
Query: 184 LREN--VCRDVDECSRPRPVC--RNGTCENLPGAYLCHCDDGFKA--GPNNDCVDVNECR 237
LRE+ +CRDVDEC+ + C R C+NL G + C C G + G C D NEC
Sbjct: 2198 LREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECH 2257
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE-----------CDELPHP-- 284
+C NGRC NT GSFRC+C G+ + C D+ + C L
Sbjct: 2258 AQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSE 2317
Query: 285 --------CG--RDGNPSCTNT----NGGYE--CSCGAGWKLVGRRCVDRDECKELPYVC 328
CG R P C Y C G+G+ GR D DEC+ L ++C
Sbjct: 2318 AVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGR---DVDECRMLAHLC 2374
Query: 329 AGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECC 388
A GEC N G + C C AG+ D TA C+D DE C Q+ +P C
Sbjct: 2375 AHGECINSLGSFRCHCQAGYTPDATATTCLD------MDE-----CS-----QVPKP-CT 2417
Query: 389 CSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGS 448
G + CP E + G +DLDEC R C CVNT G+
Sbjct: 2418 FLCKNTKGSFLCSCPRGYLLE-----EDG----RTCKDLDECTSRQHNCQF-LCVNTVGA 2467
Query: 449 FRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQ-GPDQT 506
F C CP G+ +C D DEC+ P CG +G C NT G + C+C GFT
Sbjct: 2468 FTCRCPPGFTQHHQ--ACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHG 2525
Query: 507 CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-C 565
C DV+EC +G C C N G +RC+CP G+ + C D +EC P C A C
Sbjct: 2526 CEDVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASC 2584
Query: 566 ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
N +G + C CP G+ A C+D++EC + CS C NT G FLC C G
Sbjct: 2585 RNTLGGFRCVCPSGFDFDQAL----GGCQDVDECAGRRGPCSYS-CANTPGGFLCGCPQG 2639
Query: 626 F 626
+
Sbjct: 2640 Y 2640
Score = 356 bits (876), Expect = 2e-97
Identities = 213/603 (35%), Positives = 278/603 (46%), Gaps = 41/603 (6%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC LC G C + P G++C C+ G++ C+DVDEC+ G G C N
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFG--SCEN 1421
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENV 188
LPG F C C GY L C D++EC D C +G C NT GSY C C + L +
Sbjct: 1422 LPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481
Query: 189 CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC 248
VD + C T + C + G + C + R G C
Sbjct: 1482 VGCVDTRAGN---CFLETHDRGDSGISCSAEIGVGVTRASCCCSLG--RAWGNPCELCPM 1536
Query: 249 RNTVGSFRCECAPGYTLTADGRNC--RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
NT +R C G + D+DEC ELP C + G+ C NT G ++C C
Sbjct: 1537 ANTT-EYRTLCPGGEGFQPNRITVILEDIDECQELPGLC-QGGD--CVNTFGSFQCECPP 1592
Query: 307 GWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKEL 364
G+ L R C D DEC +C G C N G Y C CPA + C+D RK +
Sbjct: 1593 GYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSV 1652
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMRICQGGMGRPN 422
C+ + G C + R CCCS G AW R CE CP P S ++ +C G
Sbjct: 1653 CFRHYN-GTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILC-GNQAPGF 1710
Query: 423 LTQ-------DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
LT D+DEC P +C G C+N GSFRCECP G+ L+C D DEC
Sbjct: 1711 LTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSR 1770
Query: 476 PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRC 533
C N C N G Y C+C+ G+ P CV +EC E C+ C +T GS+ C
Sbjct: 1771 ESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMC 1830
Query: 534 TCPYGYAVAADGVHCRDIDECVQEPRVCPH-ACENVVGSYICKCPEGYRRTSAPQDSENA 592
C G+ +AD C DIDEC ++P C + C+N++GSY C C G+ T
Sbjct: 1831 LCHRGFQASADQTLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGFVVT-----HNGD 1883
Query: 593 CEDINECEE-QEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGR 651
C D +EC +C G C+NT GSF C C GFE + DG +C+D T C ++G
Sbjct: 1884 CVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVD--TNECLS--LAGT 1939
Query: 652 CEP 654
C P
Sbjct: 1940 CLP 1942
Score = 343 bits (842), Expect = 2e-93
Identities = 209/655 (31%), Positives = 294/655 (44%), Gaps = 59/655 (9%)
Query: 9 SCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPI 68
SC+ +GV T+ CCCS+G AWG PCE CP + + LC G N +T + I
Sbjct: 1505 SCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDI 1564
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC +P LC+ G C +T FQC C GY + +C D+DECS C G C N
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGTCYN 1623
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTI--GSYRCECKPGYTLRE 186
G + C CP Y + C D+ + R +G C+N + R C Y + +
Sbjct: 1624 TLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHY-NGTCQNELAFNVTRKMCCCSYNIGQ 1682
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
R + C P C N +L G +D++EC E +C NG
Sbjct: 1683 AWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTG-------KPLDIDECGEIPAICANG 1735
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
C N +GSFRCEC G+ + C DVDEC PC + N C N G Y C C
Sbjct: 1736 ICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQ--NADCINIPGSYRCKCTR 1793
Query: 307 GWKL-VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
G+KL G CV R+EC+E+P VC+ G+C + G Y+C C G++ +C+D
Sbjct: 1794 GYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMD------ 1847
Query: 366 YDEWEAGRCHRARPLQ-LARPECCCSEG----------------AAWGRYCERCPAPDSA 408
DE + C + C C G G+ C ++A
Sbjct: 1848 IDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTA 1907
Query: 409 -EFMRICQGGM---GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
F +CQ G D +EC C+ G C N +GSFRC CP G+ + D
Sbjct: 1908 GSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSD-- 1965
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
C+D DEC+ +P +C GTC+N+ G ++C C PGF + C + R S C
Sbjct: 1966 HCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG-----HRCFDTRQSF---C 2017
Query: 525 HNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEP-RVCPHACENVVGSYICKCPEGYRR 582
+ +C+ P + C + E +P +CP + ++ CP G+
Sbjct: 2018 FTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCP---QEGSAAFQELCPFGHGA 2074
Query: 583 TSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
P DS ED+NEC E +C+ GVC+NTDGSF C+C G+ G +C+D
Sbjct: 2075 VPGPDDSR---EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVD 2126
Score = 337 bits (828), Expect = 1e-91
Identities = 216/646 (33%), Positives = 295/646 (45%), Gaps = 65/646 (10%)
Query: 23 CCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGT 82
CC ++G AWG+PCE C PA G VT + ++EC+ P +C G
Sbjct: 834 CCATLGAAWGSPCERCEI--DPACARGFARMTG-----VTCDD--VNECESFPGVCPNGR 884
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDV--DEC--SWGRPPCRGMAQCVNLPGAFE---C 135
C +T F+C C G D + LC DV + C W C V LPG + C
Sbjct: 885 CVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECG-----VTLPGKYRMDVC 939
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDEC 195
C G + C D + +C G +G + G +DV+EC
Sbjct: 940 CCSIGAVWGVECEACPDPESLEFASLCPRG-----LGFASRDFLSGRPFY----KDVNEC 990
Query: 196 SRPRPVCRNGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRNGRCRNTVGS 254
+C +GTC N G++ C C GF +C D++ECR +C G C NT GS
Sbjct: 991 KVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGS 1050
Query: 255 FRCECAPGYTLTAD-GRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV-- 311
F CEC PGY +NC DVDEC P C R G +CTNT+G Y+C C G +L
Sbjct: 1051 FECECFPGYESGFMLMKNCMDVDECARDPLLC-RGG--TCTNTDGSYKCQCPPGHELTAK 1107
Query: 312 GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK--------- 362
G C D DEC +C G+C N G + C C AG++ CVD +
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCD 1167
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCS---EGAAWGRYCERCPAPDSAEFMR-ICQGG- 417
C + + RC + L C+ E R C++ + R +C G
Sbjct: 1168 VHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGF 1227
Query: 418 MGRPNLTQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
M P++ D+DEC + P +C+ G C NT GSF C C GY++ C D DEC +
Sbjct: 1228 MATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVG 1287
Query: 476 PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFR 532
C + +C N G + C+C PG+ G C D+DEC C+ R C N GS+R
Sbjct: 1288 GHNCDSHASCLNIPGSFSCRCLPGWV-GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYR 1346
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSEN 591
CTC G+A DG C D DEC + +C + C N G Y C+C G+ P +
Sbjct: 1347 CTCRQGFA--GDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFD----PTEDHR 1400
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
AC+D++EC Q +LC+ G C N G F C C+ G+E G +C D
Sbjct: 1401 ACQDVDEC-AQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTD 1445
Score = 329 bits (808), Expect = 3e-89
Identities = 239/714 (33%), Positives = 308/714 (43%), Gaps = 111/714 (15%)
Query: 21 YLCCCSVGHAWGAPCEACPPRGSPAHTAL------CGEKPGEYINPV---------TNET 65
Y C C++G+ GA + C A +L C PG Y T
Sbjct: 705 YRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEIC 764
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS-WGR---PPCR 121
K +DEC P C G C + + C C G D + C D + + W + C
Sbjct: 765 KDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE 822
Query: 122 GMAQ--------CVNLPGAF-----ECR----CPPGYRLTPSLDECEDVDECGD-QRICD 163
Q C L A+ C C G+ + C+DV+EC +C
Sbjct: 823 VNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVT-CDDVNECESFPGVCP 881
Query: 164 HGDCRNTIGSYRCECKPGYTLREN--VCRDV-----------DECSRPRP--------VC 202
+G C NT GS+RCEC G L + +C DV DEC P C
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCC 941
Query: 203 RNGT-----CENLPG------AYLCHCDDGFKA----GPNNDCVDVNECREGGMVCRNGR 247
G CE P A LC GF + DVNEC+ +C +G
Sbjct: 942 SIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT 1001
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
CRNTVGSF C CA G+ L A RNC D+DEC P CG+ +C NT G +EC C G
Sbjct: 1002 CRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG---TCVNTPGSFECECFPG 1058
Query: 308 WK---LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKE 363
++ ++ + C+D DEC P +C GG C N +G Y C+CP G C D +
Sbjct: 1059 YESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECS 1118
Query: 364 L---------CYDEWEAGRC--HRARPLQLARPECC-CSEGAAWGRYCE-RCPAPDSAEF 410
L C + A +C H R C +E C+ C + +
Sbjct: 1119 LSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYR 1178
Query: 411 MRICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
QG P+ D+DEC P VC G C N G RC C DG++ PD +CVD
Sbjct: 1179 CSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVD 1238
Query: 469 ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFR--CH 525
DEC L+P IC +G C NT+G + C C G+ T C DVDEC G +C C
Sbjct: 1239 VDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCL 1298
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECV-QEPRVCPHA-CENVVGSYICKCPEGYRRT 583
N GSF C C G+ DG C D+DECV QE R P C NV GSY C C +G+
Sbjct: 1299 NIPGSFSCRCLPGWV--GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGD 1356
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
CED +EC E DLC G C+N G + C+C+ GF+P+ED C D
Sbjct: 1357 GF------FCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 290 bits (711), Expect = 2e-77
Identities = 192/556 (34%), Positives = 250/556 (44%), Gaps = 83/556 (14%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC + C GTC + GF+C C G+E C D+DECS C +C N
Sbjct: 2128 DECSV-GHPCGQGTCTNVIGGFECACADGFE-PGLMMTCEDIDECSLNPLLCA--FRCHN 2183
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICD-HG-DCRNTIGSYRCECKPGYTLR 185
G++ C CP GY L C DVDEC D Q+ C G +C+N IG++ C C PG
Sbjct: 2184 TEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPL 2243
Query: 186 ENV---CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF------------KAGP---- 226
C D +EC +C NG C N G++ C CD+GF + GP
Sbjct: 2244 PGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAE 2303
Query: 227 -----------NNDCVDVNECREGGMVCRNGRCRNT----VGSFRCECAPGYTLTADGRN 271
+++ V EC GG RC ++R C G TA+GR
Sbjct: 2304 VLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGR- 2362
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK--LVGRRCVDRDECKELPYVCA 329
DVDEC L H C C N+ G + C C AG+ C+D DEC ++P C
Sbjct: 2363 --DVDECRMLAHLCAHG---ECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCT 2417
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C+N G ++C CP G+ ++ C D DE + R H + L C
Sbjct: 2418 F-LCKNTKGSFLCSCPRGYLLEEDGRTCKD------LDECTS-RQHNCQFL------CVN 2463
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGS 448
+ GA + RCP P + + C D DEC +P C G C NT GS
Sbjct: 2464 TVGA----FTCRCP-PGFTQHHQACF----------DNDECSAQPGPCGAHGHCHNTPGS 2508
Query: 449 FRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-C 507
FRCEC G+ L G C D +EC P C +G C N GGY C C GFTQ C
Sbjct: 2509 FRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQC 2566
Query: 508 VDVDECAEGRASC-TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
VD +ECA +C + C NT G FRC CP G+ C+D+DEC C ++C
Sbjct: 2567 VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYSCA 2626
Query: 567 NVVGSYICKCPEGYRR 582
N G ++C CP+GY R
Sbjct: 2627 NTPGGFLCGCPQGYFR 2642
Score = 290 bits (711), Expect = 2e-77
Identities = 195/525 (37%), Positives = 244/525 (46%), Gaps = 87/525 (16%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC--RGMAQ 125
IDEC + P LC CH+T + C C GY +CRDVDEC+ G+ C RGM +
Sbjct: 2167 IDECSLNPLLCA-FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGM-E 2224
Query: 126 CVNLPGAFECRCPPGYRLTPSLDE-CEDVDECGDQR-ICDHGDCRNTIGSYRCECKPGY- 182
C NL G F C CPPG R P E C D +EC Q +C +G C NT GS+RC+C G+
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 183 ---TLRE---------------NVCRDVDECS----RPRPVCRNGT-----CE--NLPG- 212
TL E +CR + S R C G CE LPG
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGT 2344
Query: 213 -AYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRN 271
AY C G +G + DV+ECR +C +G C N++GSFRC C GYT A
Sbjct: 2345 SAYRKLCPHG--SGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATT 2402
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCA 329
C D+DEC ++P PC C NT G + CSC G+ L GR C D DEC + C
Sbjct: 2403 CLDMDECSQVPKPC----TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQ 2458
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C N G + C CP G+ + + C+D E A+P C
Sbjct: 2459 F-LCVNTVGAFTCRCPPGFT----------QHHQACFDNDECS----------AQPGPCG 2497
Query: 390 SEGAAWGRYCERCPAPDSAEFMR---ICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTD 446
+ G +C P E + + G G +D++EC P C G C N
Sbjct: 2498 AHG-----HCHNTPGSFRCECHQGFTLVSSGHG----CEDVNECD-GPHRCQHG-CQNQL 2546
Query: 447 GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT 506
G +RC CP G+ CVD +ECAL P CG+ +C NT GG+ C C GF DQ
Sbjct: 2547 GGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDF--DQA 2604
Query: 507 ---CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC 548
C DVDECA R C++ C NT G F C CP GY A G HC
Sbjct: 2605 LGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG-HC 2648
Score = 287 bits (704), Expect = 1e-76
Identities = 241/778 (30%), Positives = 309/778 (39%), Gaps = 109/778 (14%)
Query: 122 GMAQCVNLPGAFECR--CPPGYRLTPSLDECED---VDECGDQRICDHG-DCRN--TIGS 173
G +QCV +P CR C G+ P+L C D CG R C N T
Sbjct: 77 GRSQCV-VP---ICRRACGEGFCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMNGGTCRG 132
Query: 174 YRCECKPGYTLRENVCRDVDECSRPRPVCRNG-------TCENLPGAYLCHCDDGFKAGP 226
C C+ GYT VC C R C NG C + G C+ ++ GP
Sbjct: 133 ASCLCQKGYT--GTVCGQ-PICDRG---CHNGGRCIGPNRCACVYGFMGPQCERDYRTGP 186
Query: 227 NNDCVDVNECREG--GMVCRNGRCRNTVG---SFRCECAP--------GYTLTADGRNCR 273
V C+ G+VC C TVG CE P G+ C+
Sbjct: 187 CFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQ 246
Query: 274 DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPY-VCAGGE 332
DVDEC +P C G SC N G + C C G +L D + V GG
Sbjct: 247 DVDECQAVPGLC--QGG-SCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGR 303
Query: 333 CRNFNGGYV----CECPAG--WRFDKTAAVCV----DERKELCYDEWEAGRCHRAR-PLQ 381
C G+ C C G W +C +E ++LC H P
Sbjct: 304 CAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGL 363
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
L R + +G L Q +D CR ++C+ GR
Sbjct: 364 LGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGR 423
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
C+ T S+RCEC GY G C+D DEC P C +G C N G Y C+C PGF
Sbjct: 424 CLPTPSSYRCECNVGYTQDVRG-ECIDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQA 480
Query: 502 GPD-QTCVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPR 559
P Q CVDVDEC C RC NT GSF+C C G+ ++ DG +C D +EC
Sbjct: 481 TPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 560 VCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFL 619
C N GS+ C C G+ AP + C DI+EC + +C G C NT+GSF
Sbjct: 541 CVNGVCLNEDGSFSCLCKPGF--LLAP--GGHYCMDIDEC-QTPGICVNGHCTNTEGSFR 595
Query: 620 CDCDAGFEPSEDGTDCIDRRT-GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXG 678
C C G DG C+D TCY ++ G C G
Sbjct: 596 CQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSC--------------------ARPFPG 635
Query: 679 HVTKAQCCC-TLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXX 737
VTK++CCC +G C+LCPA S LC++
Sbjct: 636 TVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSS----------------GLGITTD 679
Query: 738 XXXXLDVFADVDECAAIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ 793
+ D + CA G+C G +RCVC GY +G+ C DVDECA+ CD
Sbjct: 680 GRDINECALDPEVCA--NGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDN 737
Query: 794 -LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
C N+ GSY C C G+ +D C+DVDEC + +C N GSY C C G
Sbjct: 738 GWCQNSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPG 794
Score = 263 bits (644), Expect = 2e-69
Identities = 204/618 (33%), Positives = 258/618 (41%), Gaps = 70/618 (11%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGA-PC-EACPPRGSPAHTALCGEK-------PGEYINP 60
CAG + T+ CCC G W A P E CPPRGS LC ++ PG +
Sbjct: 304 CAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGL 363
Query: 61 VTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+ + + + P P H + G + T+ L + +D C C
Sbjct: 364 LGFGSNGMGP-PLGPARLNP---HGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLC 419
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
+C+ P ++ C C GY EC DVDEC C HGDC N G+Y C C P
Sbjct: 420 LN-GRCLPTPSSYRCECNVGY-TQDVRGECIDVDECTSSP-CHHGDCVNIPGTYHCRCYP 476
Query: 181 GY--TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECR 237
G+ T C DVDEC +C G C N G++ C C+ GF+ P+ +CVD NEC
Sbjct: 477 GFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECA 536
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTN 297
M C NG C N GSF C C PG+ L G C D+DEC + P C N CTNT
Sbjct: 537 TSTM-CVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDEC-QTPGIC---VNGHCTNTE 591
Query: 298 GGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGEC-RNFNGGYV---CECP-AGWRF 350
G + C C G + GR CVD G C R F G C C F
Sbjct: 592 GSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGF 651
Query: 351 DKTAAVC----VDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPD 406
+ +C E + LC R PE C + R RC
Sbjct: 652 GEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNL 711
Query: 407 SAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
E G G+ D+DEC + +C G C N+ GS+ C CP G+ D C
Sbjct: 712 GYE-----AGASGKD--CTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEIC 764
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDE--C----AEGR-- 517
D DEC P C +G C N G Y C+C PG P T C+D + C E R
Sbjct: 765 KDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE 822
Query: 518 -----ASCTFRCHNTAGSF------RC----TCPYGYAVAADGVHCRDIDECVQEPRVCP 562
AS C T G+ RC C G+A GV C D++EC P VCP
Sbjct: 823 VNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFA-RMTGVTCDDVNECESFPGVCP 881
Query: 563 HA-CENVVGSYICKCPEG 579
+ C N GS+ C+CPEG
Sbjct: 882 NGRCVNTAGSFRCECPEG 899
Score = 258 bits (633), Expect = 5e-68
Identities = 221/687 (32%), Positives = 281/687 (40%), Gaps = 129/687 (18%)
Query: 40 PRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYE 99
P GS A + PG + ID C LC G C TP+ ++C C+ GY
Sbjct: 382 PHGSDAR-GIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYT 440
Query: 100 HDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GD 158
D C DVDEC+ PC CVN+PG + CRC PG++ TP+ C DVDEC
Sbjct: 441 QDVRGE-CIDVDECT--SSPCH-HGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVS 496
Query: 159 QRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLC 216
+C G C NT GS++C C G+ L + C D +EC+ +C NG C N G++ C
Sbjct: 497 GGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECA-TSTMCVNGVCLNEDGSFSC 555
Query: 217 HCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV 275
C GF P C+D++EC+ G +C NG C NT GSFRC+C G + DGR C D
Sbjct: 556 LCKPGFLLAPGGHYCMDIDECQTPG-ICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDT 614
Query: 276 ---DEC--------DELPHP---------CGRD----GNPS--CTNTNGG-YECSCGAGW 308
C P P C G P C N ++ C +G
Sbjct: 615 HVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGL 674
Query: 309 KLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCY 366
+ GR D +EC P VCA G C N G Y C C G+ + C D
Sbjct: 675 GITTDGR---DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTD------V 725
Query: 367 DEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM---GRPNL 423
DE C A C G +C+ P S C G +
Sbjct: 726 DE-----C--------ALNSLLCDNG-----WCQNSPGSYSCS----CPPGFHFWQDTEI 763
Query: 424 TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA---------DECAL 474
+D+DEC P CV G C N GS+ C+C G L P G C+D+ E
Sbjct: 764 CKDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRC 821
Query: 475 DPRICG---NGTCSNTRG---GYECQ-------CSPGFTQGPDQTCVDVDECAEGRASC- 520
+ + G C T G G C+ C+ GF + TC DV+EC C
Sbjct: 822 EVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCP 881
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRDI-----------DEC-VQEP-----RVCPH 563
RC NTAGSFRC CP G + A G C D+ DEC V P VC
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCC 941
Query: 564 ACENVVG------------SYICKCPEGYRRTSAP-QDSENACEDINECEEQEDLCSGGV 610
+ V G + CP G S +D+NEC+ LC+ G
Sbjct: 942 SIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT 1001
Query: 611 CINTDGSFLCDCDAGFEPSEDGTDCID 637
C NT GSF C C GF +C D
Sbjct: 1002 CRNTVGSFHCACAGGFALDAQERNCTD 1028
Score = 237 bits (580), Expect = 1e-61
Identities = 170/513 (33%), Positives = 219/513 (42%), Gaps = 93/513 (18%)
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGR 287
N +D+ CR +C NGRC T S+RCEC GYT G C DVDEC P G
Sbjct: 406 NQTIDI--CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDECTSSPCHHG- 461
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECP 345
C N G Y C C G++ R CVD DEC +C G C N G + C C
Sbjct: 462 ----DCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCN 517
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
AG+ CVD + C + + C +E ++ C+ P
Sbjct: 518 AGFELSPDGKNCVDHNE-----------CATST---MCVNGVCLNEDGSFSCLCK--PG- 560
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
F+ + GG + D+DEC+ P +CV G C NT+GSFRC+C G + DG
Sbjct: 561 ----FL-LAPGG----HYCMDIDECQT-PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRV 610
Query: 466 CVDA---DEC--ALDPRICGN---GT-------CSNTRGGY--ECQCSPGFTQGPDQTCV 508
CVD C A++ C GT C+N G+ CQ P Q
Sbjct: 611 CVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALC 670
Query: 509 -----------DVDECAEGRASCTFR-CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
D++ECA C C N GS+RC C GY A G C D+DEC
Sbjct: 671 SSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECAL 730
Query: 557 EPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTD 615
+C + C+N GSY C CP G+ QD+E C+D++EC C GVC N
Sbjct: 731 NSLLCDNGWCQNSPGSYSCSCPPGFHFW---QDTE-ICKDVDECLSSP--CVSGVCRNLA 784
Query: 616 GSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXX 675
GS+ C C G GT C+D GTC+ + RCE
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE--------------------VN 824
Query: 676 XXGHVTKAQCCCTLGAAWGSECELCPAPGSPAR 708
G +++CC TLGAAWGS CE C + AR
Sbjct: 825 LQGASLRSECCATLGAAWGSPCERCEIDPACAR 857
Score = 212 bits (517), Expect = 5e-54
Identities = 157/523 (30%), Positives = 203/523 (38%), Gaps = 74/523 (14%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAW---GAPC----------EACPPRGSPAH----TALCGE 52
CA + YLC C G+ GA C + C RG T C
Sbjct: 2177 CAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVC 2236
Query: 53 KPGEYINPVTNETKPID-ECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVD 111
PG P + E D EC P LC G C +T F+C CD G++ T C D+
Sbjct: 2237 PPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIR 2296
Query: 112 E----CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDC 167
+ + CR ++ EC C G P + C +++C HG
Sbjct: 2297 QGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGS- 2355
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN 227
GYT RDVDEC +C +G C N G++ CHC G+
Sbjct: 2356 -------------GYTAEG---RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDAT 2399
Query: 228 -NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C+D++EC + C C+NT GSF C C GY L DGR C+D+DEC H C
Sbjct: 2400 ATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNC- 2457
Query: 287 RDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVC-AGGECRNFNGGYVCECP 345
C NT G + C C G+ + C D DEC P C A G C N G + CEC
Sbjct: 2458 ---QFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECH 2514
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
G+ + C D + C RC QL C C +G +C
Sbjct: 2515 QGFTLVSSGHGCEDVNE--CDGPH---RCQHGCQNQLGGYRCSCPQGFTQHSQWAQCV-- 2567
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
D +EC + P C C NT G FRC CP G+
Sbjct: 2568 --------------------DENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGG 2607
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV 508
C D DECA C +C+NT GG+ C C G+ + CV
Sbjct: 2608 CQDVDECAGRRGPCSY-SCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 180 bits (438), Expect = 2e-44
Identities = 99/242 (40%), Positives = 122/242 (50%), Gaps = 22/242 (9%)
Query: 414 CQGGMGRPNLTQ----DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
CQ G P+ T D+DEC P C C NT GSF C CP GY+L DG +C D
Sbjct: 2390 CQAGY-TPDATATTCLDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDL 2447
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNT 527
DEC C C NT G + C+C PGFTQ Q C D DEC+ C CHNT
Sbjct: 2448 DECTSRQHNC-QFLCVNTVGAFTCRCPPGFTQH-HQACFDNDECSAQPGPCGAHGHCHNT 2505
Query: 528 AGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQ 587
GSFRC C G+ + + G C D++EC P C H C+N +G Y C CP+G+ + S Q
Sbjct: 2506 PGSFRCECHQGFTLVSSGHGCEDVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHS--Q 2562
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE------PSEDGTDCIDRRTG 641
++ C D NEC C C NT G F C C +GF+ +D +C RR G
Sbjct: 2563 WAQ--CVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRR-G 2619
Query: 642 TC 643
C
Sbjct: 2620 PC 2621
Score = 98.7 bits (235), Expect = 8e-20
Identities = 116/418 (27%), Positives = 158/418 (37%), Gaps = 56/418 (13%)
Query: 250 NTVGS-FRCECAPGYTLTADGRNCRDVDECDELPHPCGRD--GNPS-CTNTNGGYECSCG 305
N GS F C PG+ T GR+ V C CG P+ CT +G SCG
Sbjct: 58 NVCGSRFHAYCCPGWR-TFPGRSQCVVPICRRA---CGEGFCSQPNLCTCADGTLAPSCG 113
Query: 306 AG-WKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCE--CPAGWR-FDKTAAVCV--- 358
C++ C+ +C G G +C+ C G R CV
Sbjct: 114 VSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCACVYGF 173
Query: 359 -------DERKELCYDEWEAGRC-HRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
D R C+ + C H+ L + CC + G AWG CE CPA
Sbjct: 174 MGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHP-- 231
Query: 411 MRICQGGMGRPNL----TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
C+ G PN+ QD+DEC+ P +C GG CVN GSF C CP G+ L+ +C
Sbjct: 232 ---CRRGF-IPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAAC 287
Query: 467 VDADECALDPRICGNGTCSNTRGGY----ECQCSPG--FTQGPDQTCVDVDECAEGRASC 520
D A + G G C+ G+ +C C G + GP E + C
Sbjct: 288 EDYRAGACFSVLFG-GRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLC 346
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPE-G 579
R G P G G + + R+ PH GS P G
Sbjct: 347 AQRLPLLPGH-----P-GLFPGLLGFGSNGMGPPLGPARLNPH------GSDARGIPSLG 394
Query: 580 YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
++ + N DI C +LC G C+ T S+ C+C+ G+ G +CID
Sbjct: 395 PGNSNIGTATLNQTIDI--CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRG-ECID 449
Score = 98.3 bits (234), Expect = 1e-19
Identities = 46/113 (40%), Positives = 57/113 (50%), Gaps = 9/113 (7%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL--CHNT 798
D+DEC + C G F C C PG+ + C D DEC+ +P PC CHNT
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNT 2505
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
GS+ C C G+ L G C DV+EC+ H CQ C N G Y CSC G+
Sbjct: 2506 PGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHGCQNQLGGYRCSCPQGF 2557
Score = 97.9 bits (233), Expect = 1e-19
Identities = 51/124 (41%), Positives = 61/124 (49%), Gaps = 11/124 (8%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHN 797
D DECA LC APG +RC C G+ P + C DVDECA C N
Sbjct: 1362 DRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCEN 1421
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRG 855
G + C+C GYELD G NC D++EC + +C NT GSY CSC +E G
Sbjct: 1422 LPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481
Query: 856 DACV 859
CV
Sbjct: 1482 VGCV 1485
Score = 89.0 bits (211), Expect = 6e-17
Identities = 39/103 (37%), Positives = 54/103 (52%), Gaps = 4/103 (3%)
Query: 761 GRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDEDGA 817
G +RC C G+ + C D +ECA+ PP C C NT G + C+C +G++ D+
Sbjct: 2547 GGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALG 2606
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
C+DVDEC C C+NT G + C C GY + G CV
Sbjct: 2607 GCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 84.2 bits (199), Expect = 2e-15
Identities = 49/125 (39%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQ--LC 795
DVDEC P +C G F C C GY R C+DVDEC V CD C
Sbjct: 1238 DVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASC 1297
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEK 853
N GS+ C C G+ DG C D+DEC H C C N GSY C+C G+
Sbjct: 1298 LNIPGSFSCRCLPGWV--GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355
Query: 854 RGDAC 858
G C
Sbjct: 1356 DGFFC 1360
Score = 80.6 bits (190), Expect = 2e-14
Identities = 44/117 (37%), Positives = 53/117 (45%), Gaps = 12/117 (10%)
Query: 747 DVDECAAIPGLCA--------PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCH 796
D DEC+A PG C PG FRC C G+ +G C DV+EC P C C
Sbjct: 2485 DNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHGCQ 2543
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYE 852
N G Y C C G+ A C D +EC TC C NT G + C C G++
Sbjct: 2544 NQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFD 2600
Score = 73.3 bits (172), Expect = 3e-12
Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 7/95 (7%)
Query: 15 GVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIM 74
G+ TK LCC +VG AWG PCE CP + P + G N T + +DEC +
Sbjct: 202 GLVCTKALCCATVGRAWGLPCELCPAQPHPC-------RRGFIPNIHTGACQDVDECQAV 254
Query: 75 PQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
P LC+ G+C + F C C G+ ++S C D
Sbjct: 255 PGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 70.9 bits (166), Expect = 2e-11
Identities = 45/120 (37%), Positives = 58/120 (48%), Gaps = 12/120 (10%)
Query: 751 CAAIPGLCAPGRFRCVCG---PGYRP---AGEVCADVDECAVRPPPC-DQLCHNTDGSYD 803
C A P +P ++ +CG PG+ G+ D+DEC P C + +C N GS+
Sbjct: 1688 CEACPTPISPD-YQILCGNQAPGFLTDIHTGKPL-DIDECGEIPAICANGICINQIGSFR 1745
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE-KRGDACVG 860
C C G+ + C DVDEC CQQ C N GSY C C GY+ G ACVG
Sbjct: 1746 CECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVG 1805
Score = 50.4 bits (115), Expect = 3e-05
Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 32/149 (21%)
Query: 743 DVFADVDECAAIP---GLCA--PGRFRCVCGPGYR--PAGEVCADVDE--C--AVRPPPC 791
++ DVDEC + P G+C G + C CGPG R P+G C D + C ++ C
Sbjct: 762 EICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRC 821
Query: 792 DQLCHNTDGSYDCLCRTGY---------ELDE---------DGANCRDVDECERDTHTCQ 833
+ +C G E+D G C DV+ECE C
Sbjct: 822 EVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCP 881
Query: 834 Q-ICSNTEGSYECSCEDG--YEKRGDACV 859
C NT GS+ C C +G + G CV
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCV 910
Score = 48.0 bits (109), Expect = 1e-04
Identities = 57/195 (29%), Positives = 74/195 (37%), Gaps = 34/195 (17%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
GTC G C C GY T +C C G C +C+ G C C G
Sbjct: 128 GTCR----GASCLCQKGY----TGTVCGQ-PICDRG---CHNGGRCI---GPNRCACVYG 172
Query: 141 YRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRP 200
+ + P +CE D R G C +G C+ + L VC C+
Sbjct: 173 F-MGP---QCER-----DYRT---GPCFGQVGPEGCQ----HQLTGLVCTKALCCATVGR 216
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCEC 259
CE P A C GF + C DV+EC+ +C+ G C N VGSF C C
Sbjct: 217 AW-GLPCELCP-AQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRC 274
Query: 260 APGYTLTADGRNCRD 274
G+ L+ C D
Sbjct: 275 PVGHRLSDSSAACED 289
Score = 38.7 bits (86), Expect = 0.087
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGY 851
CR G+ + C+DVDEC+ CQ C N GS+ C C G+
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGH 278
>AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 728 bits (1799), Expect = 0.0
Identities = 355/869 (40%), Positives = 460/869 (52%), Gaps = 64/869 (7%)
Query: 9 SCAGAVGVPQTKYLCCCS--VGHAWGAPCEACPPRGSPAHTALCGEK-PGEYINPVTNET 65
+C + T+ +CCCS +G AW PCEACP SP + LCG + PG + T +
Sbjct: 1660 TCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKP 1719
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ 125
IDEC +P +C G C + F+C C G+ +++ C DVDEC PC+ A
Sbjct: 1720 LDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCECKPGY-- 182
C+N+PG++ C+C GY+L+P C +EC + +C HGDC +T GSY C C G+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPG-GACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQA 1838
Query: 183 TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE-GGM 241
+ + +C D+DEC R +P C NGTC+N+ G+Y C C GF N DCVD +EC G
Sbjct: 1839 SADQTLCMDIDECDR-QP-CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 242 VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
VCR G C NT GSF C C G+ LTADG+NC D +EC L C G +C N G +
Sbjct: 1897 VCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTC-LPG--TCQNLEGSFR 1953
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER 361
C C G+++ C+D DEC E P +C G C N G + C CP G+ C D R
Sbjct: 1954 CICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTR 2013
Query: 362 KELCYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMRICQGGMG 419
+ C+ +EAG+C + + CCCS+ G WG CE CP SA F +C G G
Sbjct: 2014 QSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHG 2073
Query: 420 R----PNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
+ +D++EC P VC G CVNTDGSFRCECP GY L G++CVD DEC++
Sbjct: 2074 AVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG 2133
Query: 476 PRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
CG GTC+N GG+EC C+ GF G TC D+DEC+ C FRCHNT GS+ CTC
Sbjct: 2134 -HPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTC 2192
Query: 536 PYGYAVAADGVHCRDIDECVQEPRVCPHA----CENVVGSYICKCPEGYRRTSAPQDSEN 591
P GY + DG CRD+DEC + C HA C+N++G++ C CP G R P E
Sbjct: 2193 PAGYTLREDGAMCRDVDECADGQQDC-HARGMECKNLIGTFACVCPPGMR--PLPGSGE- 2248
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGR 651
C D NEC Q DLC G C+NT GSF CDCD GF+PS T+C D R G C+ ++
Sbjct: 2249 GCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTM 2308
Query: 652 CEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDL 711
C VT+A+CCC G WG CELCP PG+ A L
Sbjct: 2309 CR------------------SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKL 2350
Query: 712 CTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCAPGRFRCVCGPGY 771
C + A + CA + + G FRC C GY
Sbjct: 2351 CP--------------HGSGYTAEGRDVDECRMLAHL--CAHGECINSLGSFRCHCQAGY 2394
Query: 772 RP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDT 829
P C D+DEC+ P PC LC NT GS+ C C GY L+EDG C+D+DEC
Sbjct: 2395 TPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQ 2454
Query: 830 HTCQQICSNTEGSYECSCEDGYEKRGDAC 858
H CQ +C NT G++ C C G+ + AC
Sbjct: 2455 HNCQFLCVNTVGAFTCRCPPGFTQHHQAC 2483
Score = 457 bits (1126), Expect = e-128
Identities = 268/748 (35%), Positives = 342/748 (45%), Gaps = 83/748 (11%)
Query: 151 EDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTLR-ENVCRDVDECSRPRPVCRNGTCE 208
+ +D C +C +G C T SYRCEC GYT C DVDEC+ C +G C
Sbjct: 407 QTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSP--CHHGDCV 464
Query: 209 NLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTA 267
N+PG Y C C GF+A P CVDV+EC G +C GRC NT GSF+C C G+ L+
Sbjct: 465 NIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSP 524
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELP 325
DG+NC D +EC C N C N +G + C C G+ L G C+D DEC + P
Sbjct: 525 DGKNCVDHNEC-ATSTMCV---NGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDEC-QTP 579
Query: 326 YVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER-KELCYDEWEAGRCHRARPLQLAR 384
+C G C N G + C+C G VCVD + CY E G C R P + +
Sbjct: 580 GICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTK 639
Query: 385 PECCCSE-GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCV 443
ECCC+ +G C+ CPA +SAEF +C G+G +D++EC + P+VC G C
Sbjct: 640 SECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCE 699
Query: 444 NTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
N GS+RC C GY G C D DECAL+ +C NG C N+ G Y C C PGF
Sbjct: 700 NLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQ 759
Query: 504 D-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP 562
D + C DVDEC + C N AGS+ C C G + G C D + ++
Sbjct: 760 DTEICKDVDECLSS-PCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQE 818
Query: 563 HACE-NVVGSYI---CKCPEGYRRTSAPQDSE--------------NACEDINECEEQED 604
CE N+ G+ + C G S + E C+D+NECE
Sbjct: 819 SRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPG 878
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXX 664
+C G C+NT GSF C+C G G C+D R C+ C
Sbjct: 879 VCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDEC------------ 926
Query: 665 XXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXX 724
G CCC++GA WG ECE CP P S LC
Sbjct: 927 --------GVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCP----------- 967
Query: 725 XXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLC-------APGRFRCVCGPGYRPAGEV 777
+ DV+EC PGLC G F C C G+ +
Sbjct: 968 ----RGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQE 1023
Query: 778 --CADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD-EDGANCRDVDECERDTHTC- 832
C D+DEC + P C Q C NT GS++C C GYE NC DVDEC RD C
Sbjct: 1024 RNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCW 1083
Query: 833 QQICSNTEGSYECSCEDGYE--KRGDAC 858
C+NT+GSY+C C G+E +G AC
Sbjct: 1084 GGTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Score = 440 bits (1085), Expect = e-123
Identities = 286/830 (34%), Positives = 358/830 (43%), Gaps = 101/830 (12%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+DEC P LC GTC +T ++C C G+E C D+DECS C QCV
Sbjct: 1072 VDECARDPLLCWGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH-GQCV 1130
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
N+ GAF+C C G++ TP C D++EC Q C NT GSYRC C GY+L +
Sbjct: 1131 NVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPD 1190
Query: 188 --VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCR 244
C DVDEC VC G C N+PG + C C DGF A P+ CVDV+EC +C
Sbjct: 1191 GRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICL 1250
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
+G C NT GSF C C GY + C DVDEC+ H C D + SC N G + C C
Sbjct: 1251 HGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNC--DSHASCLNIPGSFSCRC 1308
Query: 305 GAGWKLVGRRCVDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
GW G C D DEC + C+ G+C N G Y C C G+ D DE E
Sbjct: 1309 LPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAE 1368
Query: 364 --------LCYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMR- 412
C + RC C + A G C + R
Sbjct: 1369 NVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRC 1428
Query: 413 ICQGGM----GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
IC GG G N T D++EC P C+ G C+NT GS+ C CP + L P G+ CVD
Sbjct: 1429 ICNGGYELDRGGGNCT-DINEC-ADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVD 1486
Query: 469 --ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRA---SCTFR 523
A C L+ G+ G C G C C+ GRA C
Sbjct: 1487 TRAGNCFLETHDRGDS-------GISCSAEIGVGVTRASCC-----CSLGRAWGNPCELC 1534
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHC--RDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
+R CP G + + DIDEC + P +C C N GS+ C+CP GY
Sbjct: 1535 PMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGY 1594
Query: 581 RRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRT 640
+ + CEDI+EC +C G C NT G++ C C A + G +C+D R
Sbjct: 1595 HLS----EHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRK 1650
Query: 641 GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCT--LGAAWGSECE 698
C+R +G C+ E +VT+ CCC+ +G AW CE
Sbjct: 1651 SVCFRH-YNGTCQNELAF--------------------NVTRKMCCCSYNIGQAWNRPCE 1689
Query: 699 LCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLC 758
CP P SP LC N P D+DEC IP +C
Sbjct: 1690 ACPTPISPDYQILCG--NQAPGFLTDIHTGKP---------------LDIDECGEIPAIC 1732
Query: 759 AP-------GRFRCVCGPG--YRPAGEVCADVDECAVRPPPCDQL--CHNTDGSYDCLCR 807
A G FRC C G Y C DVDEC R PC Q C N GSY C C
Sbjct: 1733 ANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCT 1792
Query: 808 TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
GY+L GA C +EC + C C +TEGSY C C G++ D
Sbjct: 1793 RGYKLSPGGA-CVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASAD 1841
Score = 429 bits (1058), Expect = e-119
Identities = 232/592 (39%), Positives = 291/592 (49%), Gaps = 47/592 (7%)
Query: 1 MEWNEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
+ W+E++ C + +CCCS+G WG CEACP S +LC G
Sbjct: 919 LRWDEDE--CGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRD 976
Query: 61 VTNET---KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGR 117
+ K ++EC + P LC GTC +T F C C G+ D C D+DEC
Sbjct: 977 FLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISP 1036
Query: 118 PPCRGMAQCVNLPGAFECRCPPGYRLTPSL-DECEDVDECG-DQRICDHGDCRNTIGSYR 175
C G CVN PG+FEC C PGY L C DVDEC D +C G C NT GSY+
Sbjct: 1037 DLC-GQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCWGGTCTNTDGSYK 1095
Query: 176 CECKPGY--TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVD 232
C+C PG+ T + C D+DECS +C +G C N+ GA+ C C GF++ P+ CVD
Sbjct: 1096 CQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVD 1155
Query: 233 VNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
+NECR C + C NT GS+RC C GY+L DGR C DVDEC+E P C +
Sbjct: 1156 INECRVQNGGC-DVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQG---H 1211
Query: 293 CTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRF 350
CTN GG+ C C G+ R CVD DEC P++C G+C N G +VC C G+
Sbjct: 1212 CTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMV 1271
Query: 351 DKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
K A C D DE E G H C A+ C P S
Sbjct: 1272 RKGATGCSD------VDECEVGG-HN------------CDSHAS----CLNIPGSFSC-- 1306
Query: 411 MRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
R G +G DLDEC + C G C+N GS+RC C G+ A DG C D
Sbjct: 1307 -RCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCEDR 1363
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTA 528
DECA + +C NG C N GGY C+C GF D + C DVDECA+G C N
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLP 1423
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGY 580
G FRC C GY + G +C DI+EC C N GSY+C CP+ +
Sbjct: 1424 GMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDF 1475
Score = 406 bits (1000), Expect = e-112
Identities = 237/654 (36%), Positives = 309/654 (47%), Gaps = 78/654 (11%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C KPG + P + IDEC P +C G C +T F+C C G +C D
Sbjct: 555 CLCKPGFLLAPGGHYCMDIDECQT-PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVD 613
Query: 110 ----------VDECSWGRP--------------PCRGMAQ-CVNLPGA----FECRCPPG 140
+++ S RP P G + C P F+ C G
Sbjct: 614 THVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSG 673
Query: 141 YRLTPSLDECEDVDECG-DQRICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSR 197
+T + D++EC D +C +G C N GSYRC C GY + C DVDEC+
Sbjct: 674 LGITT---DGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECAL 730
Query: 198 PRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFR 256
+C NG C+N PG+Y C C GF + + C DV+EC C +G CRN GS+
Sbjct: 731 NSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYT 788
Query: 257 CECAPGYTLTADGRNCRD---------VDECDELPHPCGRDGNPSCTNTNG---GYEC-- 302
C+C PG L G C D + E + G C T G G C
Sbjct: 789 CKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCER 848
Query: 303 -----SCGAGW-KLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
+C G+ ++ G C D +EC+ P VC G C N G + CECP G D + +
Sbjct: 849 CEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRL 908
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
CVD R E C+ W+ C P + CCCS GA WG CE CP P+S EF +C
Sbjct: 909 CVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPR 968
Query: 417 GM---------GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
G+ GRP +D++EC+V P +C G C NT GSF C C G+ L +C
Sbjct: 969 GLGFASRDFLSGRP-FYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCT 1027
Query: 468 DADECALDPRICGNGTCSNTRGGYECQCSPGFTQG--PDQTCVDVDECAEGRASC-TFRC 524
D DEC + P +CG GTC NT G +EC+C PG+ G + C+DVDECA C C
Sbjct: 1028 DIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCWGGTC 1087
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRT 583
NT GS++C CP G+ + A G C DIDEC +CPH C NV+G++ C C G++ T
Sbjct: 1088 TNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQST 1147
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
Q C DINEC Q C CINT+GS+ C C G+ DG C D
Sbjct: 1148 PDRQ----GCVDINECRVQNGGCDVH-CINTEGSYRCSCGQGYSLMPDGRACAD 1196
Score = 405 bits (996), Expect = e-112
Identities = 224/611 (36%), Positives = 293/611 (47%), Gaps = 53/611 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDE--------------- 112
IDEC P LC GTC ++P FQC C G+ + H C D +
Sbjct: 1970 IDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVP 2029
Query: 113 ---------CSWGRPPCRGMAQ-CVNLP----GAFECRCPPGYRLTPSLDEC-EDVDECG 157
C + P G C P AF+ CP G+ P D+ EDV+EC
Sbjct: 2030 KAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECA 2089
Query: 158 DQR-ICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAY 214
+ +C +G C NT GS+RCEC GY+L C D DECS P C GTC N+ G +
Sbjct: 2090 ENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP-CGQGTCTNVIGGF 2148
Query: 215 LCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRD 274
C C DGF+ G C D++EC ++C RC NT GS+ C C GYTL DG CRD
Sbjct: 2149 ECACADGFEPGLMMTCEDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Query: 275 VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV---GRRCVDRDECKELPYVCAGG 331
VDEC + C G C N G + C C G + + G C D +EC P +C G
Sbjct: 2208 VDECADGQQDCHARGM-ECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNG 2266
Query: 332 ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLA--RPECCC 389
C N G + C+C G++ T C D R+ C+ E C A R ECCC
Sbjct: 2267 RCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCC 2326
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
G WG CE CP P ++ + ++C G G +D+DECR+ +C G C+N+ GSF
Sbjct: 2327 GGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSF 2386
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCV 508
RC C GY +C+D DEC+ P+ C C NT+G + C C G+ D +TC
Sbjct: 2387 RCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCK 2445
Query: 509 DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC-PHA-CE 566
D+DEC + +C F C NT G+F C CP G+ C D DEC +P C H C
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQA--CFDNDECSAQPGPCGAHGHCH 2503
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
N GS+ C+C +G+ S S + CED+NEC+ C G C N G + C C GF
Sbjct: 2504 NTPGSFRCECHQGFTLVS----SGHGCEDVNECDGPH-RCQHG-CQNQLGGYRCSCPQGF 2557
Query: 627 EPSEDGTDCID 637
C+D
Sbjct: 2558 TQHSQWAQCVD 2568
Score = 395 bits (972), Expect = e-109
Identities = 287/876 (32%), Positives = 377/876 (43%), Gaps = 134/876 (15%)
Query: 21 YLCCCSVGHAW---GAPCEACPPRGSPAH--TALCGEKPGEYIN--PVTNETKP--IDEC 71
+ C C+ G+ G C P + +C PG Y+ P E P +
Sbjct: 1426 FRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCV 1485
Query: 72 DIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG 131
D C T +G C + G S C + +WG P C + N
Sbjct: 1486 DTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCC-SLGR-AWGNP-CE-LCPMANTT- 1540
Query: 132 AFECRCPPGYRLTPSLDEC--EDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTLREN- 187
+ CP G P+ ED+DEC + +C GDC NT GS++CEC PGY L E+
Sbjct: 1541 EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHT 1600
Query: 188 -VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF-KAGPNNDCVDVNECREGGMVC-- 243
+C D+DECS +C GTC N G Y C C + + N+C+D+ + VC
Sbjct: 1601 RICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKS-----VCFR 1655
Query: 244 -RNGRCRNTVGS--FRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGY 300
NG C+N + R C Y + C+ P P D C N G+
Sbjct: 1656 HYNGTCQNELAFNVTRKMCCCSYNIGQAWNR-----PCEACPTPISPDYQILCGNQAPGF 1710
Query: 301 ECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
G L D DEC E+P +CA G C N G + CECPAG+ ++ C D
Sbjct: 1711 LTDIHTGKPL------DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACED- 1763
Query: 361 RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG--M 418
DE + R P Q +C G+ RC ++ GG +
Sbjct: 1764 -----VDECGS----RESPCQ-QNADCINIPGSY------RCKCTRG---YKLSPGGACV 1804
Query: 419 GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRI 478
GR +ECR P+VC G C++T+GS+ C C G+ + D C+D DEC P
Sbjct: 1805 GR-------NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQP-- 1855
Query: 479 CGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAE--GRASCTF-RCHNTAGSFRCTC 535
CGNGTC N G Y C C PGF + CVD DEC G+ C F C NTAGSF C C
Sbjct: 1856 CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQV-CRFGHCLNTAGSFHCLC 1914
Query: 536 PYGYAVAADGVHCRDIDECVQEPRVC-PHACENVVGSYICKCPEGYRRTSAPQDSENACE 594
G+ + ADG +C D +EC+ C P C+N+ GS+ C CP G+ Q + C
Sbjct: 1915 QDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGF------QVQSDHCI 1968
Query: 595 DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEP 654
DI+EC E+ +LC G C N+ GSF C C GF S++G C D R C+ +G+C
Sbjct: 1969 DIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSV 2028
Query: 655 EXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTL--GAAWGSECELCPAPGSPARLDLC 712
+ TK +CCC+ G WG CELCP GS A +LC
Sbjct: 2029 PKAF--------------------NTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELC 2068
Query: 713 TAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCA-------PGRFRC 765
P D DV+ECA PG+C G FRC
Sbjct: 2069 ------PFGHGAVPGPD-------------DSREDVNECAENPGVCTNGVCVNTDGSFRC 2109
Query: 766 VCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
C GY G C D DEC+V P C N G ++C C G+E C D+D
Sbjct: 2110 ECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLM-MTCEDID 2168
Query: 824 ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 859
EC + C C NTEGSY C+C GY R D +
Sbjct: 2169 ECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAM 2204
Score = 380 bits (935), Expect = e-104
Identities = 219/596 (36%), Positives = 284/596 (47%), Gaps = 43/596 (7%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
CG+ G + P +DEC+ P++C G C + P G +C C G+ C D
Sbjct: 1181 CGQ--GYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVD 1238
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC--GDQRICDHGDC 167
VDEC C C N G+F C C GY + C DVDEC G H C
Sbjct: 1239 VDECDLNPHICLH-GDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASC 1297
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGP 226
N GS+ C C PG+ C D+DEC C G C N+PG+Y C C GF AG
Sbjct: 1298 LNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF-AGD 1356
Query: 227 NNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C D +EC E +C NG+C N G +RCEC G+ T D R C+DVDEC + + C
Sbjct: 1357 GFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ-GNLCA 1415
Query: 287 RDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
SC N G + C C G++L G C D +EC + P C G C N G Y+C C
Sbjct: 1416 FG---SCENLPGMFRCICNGGYELDRGGGNCTDINECAD-PVNCINGVCINTPGSYLCSC 1471
Query: 345 PAGWRFDKTAAVCVDERKELCY----DEWEAG-RCHRARPLQLARPECCCSEGAAWGRYC 399
P + + + CVD R C+ D ++G C + + R CCCS G AWG C
Sbjct: 1472 PQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPC 1531
Query: 400 ERCPAPDSAEFMRICQGGMG-RPN----LTQDLDECRVRPDVCVGGRCVNTDGSFRCECP 454
E CP ++ E+ +C GG G +PN + +D+DEC+ P +C GG CVNT GSF+CECP
Sbjct: 1532 ELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECP 1591
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ-GPDQTCVDVDEC 513
GY L+ C D DEC+ ICG GTC NT G Y C C + Q C+D+
Sbjct: 1592 PGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDM--- 1648
Query: 514 AEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVG-S 571
R S FR +N C + V C +I + P C AC +
Sbjct: 1649 ---RKSVCFRHYNGT----CQNELAFNVTRKMCCCSYNIGQAWNRP--C-EACPTPISPD 1698
Query: 572 YICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
Y C G + D DI+EC E +C+ G+CIN GSF C+C AGF
Sbjct: 1699 YQILC--GNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGF 1752
Score = 372 bits (914), Expect = e-102
Identities = 242/661 (36%), Positives = 302/661 (45%), Gaps = 88/661 (13%)
Query: 11 AGAVGVPQ----TKYLCCCSV--GHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNE 64
AG VP+ TK CCCS G WG PCE CP GS A LC G P +
Sbjct: 2023 AGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGP-DDS 2081
Query: 65 TKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+ ++EC P +C G C +T F+C C GY D T C D DECS G P C G
Sbjct: 2082 REDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP-C-GQG 2139
Query: 125 QCVNLPGAFECRCPPGYRLTPSLD-ECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYT 183
C N+ G FEC C G+ P L CED+DEC + C NT GSY C C GYT
Sbjct: 2140 TCTNVIGGFECACADGFE--PGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYT 2197
Query: 184 LREN--VCRDVDECSRPRPVC--RNGTCENLPGAYLCHCDDGFKA--GPNNDCVDVNECR 237
LRE+ +CRDVDEC+ + C R C+NL G + C C G + G C D NEC
Sbjct: 2198 LREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECH 2257
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE-----------CDELPHP-- 284
+C NGRC NT GSFRC+C G+ + C D+ + C L
Sbjct: 2258 AQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSE 2317
Query: 285 --------CG--RDGNPSCTNT----NGGYE--CSCGAGWKLVGRRCVDRDECKELPYVC 328
CG R P C Y C G+G+ GR D DEC+ L ++C
Sbjct: 2318 AVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGR---DVDECRMLAHLC 2374
Query: 329 AGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECC 388
A GEC N G + C C AG+ D TA C+D DE C Q+ +P C
Sbjct: 2375 AHGECINSLGSFRCHCQAGYTPDATATTCLD------MDE-----CS-----QVPKP-CT 2417
Query: 389 CSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGS 448
G + CP E + G +DLDEC R C CVNT G+
Sbjct: 2418 FLCKNTKGSFLCSCPRGYLLE-----EDG----RTCKDLDECTSRQHNCQF-LCVNTVGA 2467
Query: 449 FRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQ-GPDQT 506
F C CP G+ +C D DEC+ P CG +G C NT G + C+C GFT
Sbjct: 2468 FTCRCPPGFTQHHQ--ACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHG 2525
Query: 507 CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-C 565
C DV+EC +G C C N G +RC+CP G+ + C D +EC P C A C
Sbjct: 2526 CEDVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASC 2584
Query: 566 ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
N +G + C CP G+ A C+D++EC + CS C NT G FLC C G
Sbjct: 2585 RNTLGGFRCVCPSGFDFDQAL----GGCQDVDECAGRRGPCSYS-CANTPGGFLCGCPQG 2639
Query: 626 F 626
+
Sbjct: 2640 Y 2640
Score = 356 bits (876), Expect = 2e-97
Identities = 213/603 (35%), Positives = 278/603 (46%), Gaps = 41/603 (6%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC LC G C + P G++C C+ G++ C+DVDEC+ G G C N
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFG--SCEN 1421
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENV 188
LPG F C C GY L C D++EC D C +G C NT GSY C C + L +
Sbjct: 1422 LPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481
Query: 189 CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC 248
VD + C T + C + G + C + R G C
Sbjct: 1482 VGCVDTRAGN---CFLETHDRGDSGISCSAEIGVGVTRASCCCSLG--RAWGNPCELCPM 1536
Query: 249 RNTVGSFRCECAPGYTLTADGRNC--RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
NT +R C G + D+DEC ELP C + G+ C NT G ++C C
Sbjct: 1537 ANTT-EYRTLCPGGEGFQPNRITVILEDIDECQELPGLC-QGGD--CVNTFGSFQCECPP 1592
Query: 307 GWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKEL 364
G+ L R C D DEC +C G C N G Y C CPA + C+D RK +
Sbjct: 1593 GYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSV 1652
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMRICQGGMGRPN 422
C+ + G C + R CCCS G AW R CE CP P S ++ +C G
Sbjct: 1653 CFRHYN-GTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILC-GNQAPGF 1710
Query: 423 LTQ-------DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
LT D+DEC P +C G C+N GSFRCECP G+ L+C D DEC
Sbjct: 1711 LTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSR 1770
Query: 476 PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRC 533
C N C N G Y C+C+ G+ P CV +EC E C+ C +T GS+ C
Sbjct: 1771 ESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMC 1830
Query: 534 TCPYGYAVAADGVHCRDIDECVQEPRVCPH-ACENVVGSYICKCPEGYRRTSAPQDSENA 592
C G+ +AD C DIDEC ++P C + C+N++GSY C C G+ T
Sbjct: 1831 LCHRGFQASADQTLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGFVVT-----HNGD 1883
Query: 593 CEDINECEE-QEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGR 651
C D +EC +C G C+NT GSF C C GFE + DG +C+D T C ++G
Sbjct: 1884 CVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVD--TNECLS--LAGT 1939
Query: 652 CEP 654
C P
Sbjct: 1940 CLP 1942
Score = 343 bits (844), Expect = 1e-93
Identities = 231/658 (35%), Positives = 287/658 (43%), Gaps = 70/658 (10%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPID 69
C VG Q C V +PC P T C PG P +D
Sbjct: 433 CECNVGYTQDVRGECIDVDECTSSPCHHGDCVNIPG-TYHCRCYPGFQATPTRQACVDVD 491
Query: 70 ECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
EC + LC G C +T FQC C+ G+E C D +EC+ G+ C+N
Sbjct: 492 ECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGV--CLNE 549
Query: 130 PGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN-- 187
G+F C C PG+ L P C D+DEC IC +G C NT GS+RC+C G + +
Sbjct: 550 DGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGR 609
Query: 188 VCRDVD------------ECSRPRP--VCRNGTCENLPG------AYLCHCDDG--FKA- 224
VC D C+RP P V ++ C P LC + F+A
Sbjct: 610 VCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQAL 669
Query: 225 -----GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECD 279
G D D+NEC VC NG C N GS+RC C GY A G++C DVDEC
Sbjct: 670 CSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECA 729
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFN 337
C N C N+ G Y CSC G+ C D DEC P C G CRN
Sbjct: 730 LNSLLCD---NGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLA 784
Query: 338 GGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGR 397
G Y C+C G R D + C+D K C+ + + RC R ECC + GAAWG
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGS 844
Query: 398 YCERCPAPDSAEFMRICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPD 455
CERC E C G R D++EC P VC GRCVNT GSFRCECP+
Sbjct: 845 PCERC------EIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPE 898
Query: 456 GYVLAPDGLSCVDA--DECAL--DPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDV 510
G +L G CVD + C L D CG R C CS G G + + C D
Sbjct: 899 GLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDV-CCCSIGAVWGVECEACPD- 956
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH-ACENVV 569
E E + C + F P+ +D++EC P +C H C N V
Sbjct: 957 PESLEFASLCPRGLGFASRDFLSGRPF----------YKDVNECKVFPGLCTHGTCRNTV 1006
Query: 570 GSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
GS+ C C G+ A E C DI+EC DLC G C+NT GSF C+C G+E
Sbjct: 1007 GSFHCACAGGF----ALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYE 1060
Score = 343 bits (842), Expect = 2e-93
Identities = 209/655 (31%), Positives = 294/655 (44%), Gaps = 59/655 (9%)
Query: 9 SCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPI 68
SC+ +GV T+ CCCS+G AWG PCE CP + + LC G N +T + I
Sbjct: 1505 SCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDI 1564
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC +P LC+ G C +T FQC C GY + +C D+DECS C G C N
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGTCYN 1623
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTI--GSYRCECKPGYTLRE 186
G + C CP Y + C D+ + R +G C+N + R C Y + +
Sbjct: 1624 TLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHY-NGTCQNELAFNVTRKMCCCSYNIGQ 1682
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
R + C P C N +L G +D++EC E +C NG
Sbjct: 1683 AWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTG-------KPLDIDECGEIPAICANG 1735
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
C N +GSFRCEC G+ + C DVDEC PC + N C N G Y C C
Sbjct: 1736 ICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQ--NADCINIPGSYRCKCTR 1793
Query: 307 GWKL-VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
G+KL G CV R+EC+E+P VC+ G+C + G Y+C C G++ +C+D
Sbjct: 1794 GYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMD------ 1847
Query: 366 YDEWEAGRCHRARPLQ-LARPECCCSEG----------------AAWGRYCERCPAPDSA 408
DE + C + C C G G+ C ++A
Sbjct: 1848 IDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTA 1907
Query: 409 -EFMRICQGGM---GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
F +CQ G D +EC C+ G C N +GSFRC CP G+ + D
Sbjct: 1908 GSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSD-- 1965
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
C+D DEC+ +P +C GTC+N+ G ++C C PGF + C + R S C
Sbjct: 1966 HCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG-----HRCFDTRQSF---C 2017
Query: 525 HNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEP-RVCPHACENVVGSYICKCPEGYRR 582
+ +C+ P + C + E +P +CP + ++ CP G+
Sbjct: 2018 FTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCP---QEGSAAFQELCPFGHGA 2074
Query: 583 TSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
P DS ED+NEC E +C+ GVC+NTDGSF C+C G+ G +C+D
Sbjct: 2075 VPGPDDSR---EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVD 2126
Score = 335 bits (823), Expect = 4e-91
Identities = 214/646 (33%), Positives = 293/646 (45%), Gaps = 65/646 (10%)
Query: 23 CCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGT 82
CC ++G AWG+PCE C PA G VT + ++EC+ P +C G
Sbjct: 834 CCATLGAAWGSPCERCEI--DPACARGFARMTG-----VTCDD--VNECESFPGVCPNGR 884
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDV--DEC--SWGRPPCRGMAQCVNLPGAFE---C 135
C +T F+C C G D + LC DV + C W C V LPG + C
Sbjct: 885 CVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECG-----VTLPGKYRMDVC 939
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDEC 195
C G + C D + +C G +G + G +DV+EC
Sbjct: 940 CCSIGAVWGVECEACPDPESLEFASLCPRG-----LGFASRDFLSGRPFY----KDVNEC 990
Query: 196 SRPRPVCRNGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRNGRCRNTVGS 254
+C +GTC N G++ C C GF +C D++ECR +C G C NT GS
Sbjct: 991 KVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGS 1050
Query: 255 FRCECAPGYTLTAD-GRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV-- 311
F CEC PGY +NC DVDEC P C +CTNT+G Y+C C G +L
Sbjct: 1051 FECECFPGYESGFMLMKNCMDVDECARDPLLCW---GGTCTNTDGSYKCQCPPGHELTAK 1107
Query: 312 GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK--------- 362
G C D DEC +C G+C N G + C C AG++ CVD +
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCD 1167
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCS---EGAAWGRYCERCPAPDSAEFMR-ICQGG- 417
C + + RC + L C+ E R C++ + R +C G
Sbjct: 1168 VHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGF 1227
Query: 418 MGRPNLTQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
M P++ D+DEC + P +C+ G C NT GSF C C GY++ C D DEC +
Sbjct: 1228 MATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVG 1287
Query: 476 PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFR 532
C + +C N G + C+C PG+ G C D+DEC C+ R C N GS+R
Sbjct: 1288 GHNCDSHASCLNIPGSFSCRCLPGWV-GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYR 1346
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSEN 591
CTC G+A DG C D DEC + +C + C N G Y C+C G+ P +
Sbjct: 1347 CTCRQGFA--GDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFD----PTEDHR 1400
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
AC+D++EC Q +LC+ G C N G F C C+ G+E G +C D
Sbjct: 1401 ACQDVDEC-AQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTD 1445
Score = 328 bits (806), Expect = 5e-89
Identities = 239/714 (33%), Positives = 308/714 (43%), Gaps = 111/714 (15%)
Query: 21 YLCCCSVGHAWGAPCEACPPRGSPAHTAL------CGEKPGEYINPV---------TNET 65
Y C C++G+ GA + C A +L C PG Y T
Sbjct: 705 YRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEIC 764
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS-WGR---PPCR 121
K +DEC P C G C + + C C G D + C D + + W + C
Sbjct: 765 KDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE 822
Query: 122 GMAQ--------CVNLPGAF-----ECR----CPPGYRLTPSLDECEDVDECGD-QRICD 163
Q C L A+ C C G+ + C+DV+EC +C
Sbjct: 823 VNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVT-CDDVNECESFPGVCP 881
Query: 164 HGDCRNTIGSYRCECKPGYTLREN--VCRDV-----------DECSRPRP--------VC 202
+G C NT GS+RCEC G L + +C DV DEC P C
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCC 941
Query: 203 RNGT-----CENLPG------AYLCHCDDGFKA----GPNNDCVDVNECREGGMVCRNGR 247
G CE P A LC GF + DVNEC+ +C +G
Sbjct: 942 SIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT 1001
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
CRNTVGSF C CA G+ L A RNC D+DEC P CG+ +C NT G +EC C G
Sbjct: 1002 CRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG---TCVNTPGSFECECFPG 1058
Query: 308 WK---LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKE 363
++ ++ + C+D DEC P +C GG C N +G Y C+CP G C D +
Sbjct: 1059 YESGFMLMKNCMDVDECARDPLLCWGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECS 1118
Query: 364 L---------CYDEWEAGRC--HRARPLQLARPECC-CSEGAAWGRYCE-RCPAPDSAEF 410
L C + A +C H R C +E C+ C + +
Sbjct: 1119 LSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYR 1178
Query: 411 MRICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
QG P+ D+DEC P VC G C N G RC C DG++ PD +CVD
Sbjct: 1179 CSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVD 1238
Query: 469 ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFR--CH 525
DEC L+P IC +G C NT+G + C C G+ T C DVDEC G +C C
Sbjct: 1239 VDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCL 1298
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECV-QEPRVCPHA-CENVVGSYICKCPEGYRRT 583
N GSF C C G+ DG C D+DECV QE R P C NV GSY C C +G+
Sbjct: 1299 NIPGSFSCRCLPGWV--GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGD 1356
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
CED +EC E DLC G C+N G + C+C+ GF+P+ED C D
Sbjct: 1357 GF------FCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 290 bits (711), Expect = 2e-77
Identities = 192/556 (34%), Positives = 250/556 (44%), Gaps = 83/556 (14%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC + C GTC + GF+C C G+E C D+DECS C +C N
Sbjct: 2128 DECSV-GHPCGQGTCTNVIGGFECACADGFE-PGLMMTCEDIDECSLNPLLCA--FRCHN 2183
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICD-HG-DCRNTIGSYRCECKPGYTLR 185
G++ C CP GY L C DVDEC D Q+ C G +C+N IG++ C C PG
Sbjct: 2184 TEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPL 2243
Query: 186 ENV---CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF------------KAGP---- 226
C D +EC +C NG C N G++ C CD+GF + GP
Sbjct: 2244 PGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAE 2303
Query: 227 -----------NNDCVDVNECREGGMVCRNGRCRNT----VGSFRCECAPGYTLTADGRN 271
+++ V EC GG RC ++R C G TA+GR
Sbjct: 2304 VLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGR- 2362
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK--LVGRRCVDRDECKELPYVCA 329
DVDEC L H C C N+ G + C C AG+ C+D DEC ++P C
Sbjct: 2363 --DVDECRMLAHLCAHG---ECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCT 2417
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C+N G ++C CP G+ ++ C D DE + R H + L C
Sbjct: 2418 F-LCKNTKGSFLCSCPRGYLLEEDGRTCKD------LDECTS-RQHNCQFL------CVN 2463
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGS 448
+ GA + RCP P + + C D DEC +P C G C NT GS
Sbjct: 2464 TVGA----FTCRCP-PGFTQHHQACF----------DNDECSAQPGPCGAHGHCHNTPGS 2508
Query: 449 FRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-C 507
FRCEC G+ L G C D +EC P C +G C N GGY C C GFTQ C
Sbjct: 2509 FRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQC 2566
Query: 508 VDVDECAEGRASC-TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
VD +ECA +C + C NT G FRC CP G+ C+D+DEC C ++C
Sbjct: 2567 VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYSCA 2626
Query: 567 NVVGSYICKCPEGYRR 582
N G ++C CP+GY R
Sbjct: 2627 NTPGGFLCGCPQGYFR 2642
Score = 290 bits (711), Expect = 2e-77
Identities = 195/525 (37%), Positives = 244/525 (46%), Gaps = 87/525 (16%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC--RGMAQ 125
IDEC + P LC CH+T + C C GY +CRDVDEC+ G+ C RGM +
Sbjct: 2167 IDECSLNPLLCA-FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGM-E 2224
Query: 126 CVNLPGAFECRCPPGYRLTPSLDE-CEDVDECGDQR-ICDHGDCRNTIGSYRCECKPGY- 182
C NL G F C CPPG R P E C D +EC Q +C +G C NT GS+RC+C G+
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 183 ---TLRE---------------NVCRDVDECS----RPRPVCRNGT-----CE--NLPG- 212
TL E +CR + S R C G CE LPG
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGT 2344
Query: 213 -AYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRN 271
AY C G +G + DV+ECR +C +G C N++GSFRC C GYT A
Sbjct: 2345 SAYRKLCPHG--SGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATT 2402
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCA 329
C D+DEC ++P PC C NT G + CSC G+ L GR C D DEC + C
Sbjct: 2403 CLDMDECSQVPKPC----TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQ 2458
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C N G + C CP G+ + + C+D E A+P C
Sbjct: 2459 F-LCVNTVGAFTCRCPPGFT----------QHHQACFDNDECS----------AQPGPCG 2497
Query: 390 SEGAAWGRYCERCPAPDSAEFMR---ICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTD 446
+ G +C P E + + G G +D++EC P C G C N
Sbjct: 2498 AHG-----HCHNTPGSFRCECHQGFTLVSSGHG----CEDVNECD-GPHRCQHG-CQNQL 2546
Query: 447 GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT 506
G +RC CP G+ CVD +ECAL P CG+ +C NT GG+ C C GF DQ
Sbjct: 2547 GGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDF--DQA 2604
Query: 507 ---CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC 548
C DVDECA R C++ C NT G F C CP GY A G HC
Sbjct: 2605 LGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG-HC 2648
Score = 287 bits (704), Expect = 1e-76
Identities = 241/778 (30%), Positives = 309/778 (39%), Gaps = 109/778 (14%)
Query: 122 GMAQCVNLPGAFECR--CPPGYRLTPSLDECED---VDECGDQRICDHG-DCRN--TIGS 173
G +QCV +P CR C G+ P+L C D CG R C N T
Sbjct: 77 GRSQCV-VP---ICRRACGEGFCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMNGGTCRG 132
Query: 174 YRCECKPGYTLRENVCRDVDECSRPRPVCRNG-------TCENLPGAYLCHCDDGFKAGP 226
C C+ GYT VC C R C NG C + G C+ ++ GP
Sbjct: 133 ASCLCQKGYT--GTVCGQ-PICDRG---CHNGGRCIGPNRCACVYGFMGPQCERDYRTGP 186
Query: 227 NNDCVDVNECREG--GMVCRNGRCRNTVG---SFRCECAP--------GYTLTADGRNCR 273
V C+ G+VC C TVG CE P G+ C+
Sbjct: 187 CFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQ 246
Query: 274 DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPY-VCAGGE 332
DVDEC +P C G SC N G + C C G +L D + V GG
Sbjct: 247 DVDECQAVPGLC--QGG-SCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGR 303
Query: 333 CRNFNGGYV----CECPAG--WRFDKTAAVCV----DERKELCYDEWEAGRCHRAR-PLQ 381
C G+ C C G W +C +E ++LC H P
Sbjct: 304 CAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGL 363
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
L R + +G L Q +D CR ++C+ GR
Sbjct: 364 LGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGR 423
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
C+ T S+RCEC GY G C+D DEC P C +G C N G Y C+C PGF
Sbjct: 424 CLPTPSSYRCECNVGYTQDVRG-ECIDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQA 480
Query: 502 GPD-QTCVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPR 559
P Q CVDVDEC C RC NT GSF+C C G+ ++ DG +C D +EC
Sbjct: 481 TPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 560 VCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFL 619
C N GS+ C C G+ AP + C DI+EC + +C G C NT+GSF
Sbjct: 541 CVNGVCLNEDGSFSCLCKPGF--LLAP--GGHYCMDIDEC-QTPGICVNGHCTNTEGSFR 595
Query: 620 CDCDAGFEPSEDGTDCIDRRT-GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXG 678
C C G DG C+D TCY ++ G C G
Sbjct: 596 CQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSC--------------------ARPFPG 635
Query: 679 HVTKAQCCC-TLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXX 737
VTK++CCC +G C+LCPA S LC++
Sbjct: 636 TVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSS----------------GLGITTD 679
Query: 738 XXXXLDVFADVDECAAIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ 793
+ D + CA G+C G +RCVC GY +G+ C DVDECA+ CD
Sbjct: 680 GRDINECALDPEVCA--NGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDN 737
Query: 794 -LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
C N+ GSY C C G+ +D C+DVDEC + +C N GSY C C G
Sbjct: 738 GWCQNSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPG 794
Score = 263 bits (644), Expect = 2e-69
Identities = 204/618 (33%), Positives = 258/618 (41%), Gaps = 70/618 (11%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGA-PC-EACPPRGSPAHTALCGEK-------PGEYINP 60
CAG + T+ CCC G W A P E CPPRGS LC ++ PG +
Sbjct: 304 CAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGL 363
Query: 61 VTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+ + + + P P H + G + T+ L + +D C C
Sbjct: 364 LGFGSNGMGP-PLGPARLNP---HGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLC 419
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
+C+ P ++ C C GY EC DVDEC C HGDC N G+Y C C P
Sbjct: 420 LN-GRCLPTPSSYRCECNVGY-TQDVRGECIDVDECTSSP-CHHGDCVNIPGTYHCRCYP 476
Query: 181 GY--TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECR 237
G+ T C DVDEC +C G C N G++ C C+ GF+ P+ +CVD NEC
Sbjct: 477 GFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECA 536
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTN 297
M C NG C N GSF C C PG+ L G C D+DEC + P C N CTNT
Sbjct: 537 TSTM-CVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDEC-QTPGIC---VNGHCTNTE 591
Query: 298 GGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGEC-RNFNGGYV---CECP-AGWRF 350
G + C C G + GR CVD G C R F G C C F
Sbjct: 592 GSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGF 651
Query: 351 DKTAAVC----VDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPD 406
+ +C E + LC R PE C + R RC
Sbjct: 652 GEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNL 711
Query: 407 SAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
E G G+ D+DEC + +C G C N+ GS+ C CP G+ D C
Sbjct: 712 GYE-----AGASGKD--CTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEIC 764
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDE--C----AEGR-- 517
D DEC P C +G C N G Y C+C PG P T C+D + C E R
Sbjct: 765 KDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE 822
Query: 518 -----ASCTFRCHNTAGSF------RC----TCPYGYAVAADGVHCRDIDECVQEPRVCP 562
AS C T G+ RC C G+A GV C D++EC P VCP
Sbjct: 823 VNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFA-RMTGVTCDDVNECESFPGVCP 881
Query: 563 HA-CENVVGSYICKCPEG 579
+ C N GS+ C+CPEG
Sbjct: 882 NGRCVNTAGSFRCECPEG 899
Score = 258 bits (633), Expect = 5e-68
Identities = 221/687 (32%), Positives = 281/687 (40%), Gaps = 129/687 (18%)
Query: 40 PRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYE 99
P GS A + PG + ID C LC G C TP+ ++C C+ GY
Sbjct: 382 PHGSDAR-GIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYT 440
Query: 100 HDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GD 158
D C DVDEC+ PC CVN+PG + CRC PG++ TP+ C DVDEC
Sbjct: 441 QDVRGE-CIDVDECT--SSPCH-HGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVS 496
Query: 159 QRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLC 216
+C G C NT GS++C C G+ L + C D +EC+ +C NG C N G++ C
Sbjct: 497 GGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECA-TSTMCVNGVCLNEDGSFSC 555
Query: 217 HCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV 275
C GF P C+D++EC+ G +C NG C NT GSFRC+C G + DGR C D
Sbjct: 556 LCKPGFLLAPGGHYCMDIDECQTPG-ICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDT 614
Query: 276 ---DEC--------DELPHP---------CGRD----GNPS--CTNTNGG-YECSCGAGW 308
C P P C G P C N ++ C +G
Sbjct: 615 HVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGL 674
Query: 309 KLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCY 366
+ GR D +EC P VCA G C N G Y C C G+ + C D
Sbjct: 675 GITTDGR---DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTD------V 725
Query: 367 DEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM---GRPNL 423
DE C A C G +C+ P S C G +
Sbjct: 726 DE-----C--------ALNSLLCDNG-----WCQNSPGSYSCS----CPPGFHFWQDTEI 763
Query: 424 TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA---------DECAL 474
+D+DEC P CV G C N GS+ C+C G L P G C+D+ E
Sbjct: 764 CKDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRC 821
Query: 475 DPRICG---NGTCSNTRG---GYECQ-------CSPGFTQGPDQTCVDVDECAEGRASC- 520
+ + G C T G G C+ C+ GF + TC DV+EC C
Sbjct: 822 EVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCP 881
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRDI-----------DEC-VQEP-----RVCPH 563
RC NTAGSFRC CP G + A G C D+ DEC V P VC
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCC 941
Query: 564 ACENVVG------------SYICKCPEGYRRTSAP-QDSENACEDINECEEQEDLCSGGV 610
+ V G + CP G S +D+NEC+ LC+ G
Sbjct: 942 SIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT 1001
Query: 611 CINTDGSFLCDCDAGFEPSEDGTDCID 637
C NT GSF C C GF +C D
Sbjct: 1002 CRNTVGSFHCACAGGFALDAQERNCTD 1028
Score = 237 bits (580), Expect = 1e-61
Identities = 170/513 (33%), Positives = 219/513 (42%), Gaps = 93/513 (18%)
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGR 287
N +D+ CR +C NGRC T S+RCEC GYT G C DVDEC P G
Sbjct: 406 NQTIDI--CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDECTSSPCHHG- 461
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECP 345
C N G Y C C G++ R CVD DEC +C G C N G + C C
Sbjct: 462 ----DCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCN 517
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
AG+ CVD + C + + C +E ++ C+ P
Sbjct: 518 AGFELSPDGKNCVDHNE-----------CATST---MCVNGVCLNEDGSFSCLCK--PG- 560
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
F+ + GG + D+DEC+ P +CV G C NT+GSFRC+C G + DG
Sbjct: 561 ----FL-LAPGG----HYCMDIDECQT-PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRV 610
Query: 466 CVDA---DEC--ALDPRICGN---GT-------CSNTRGGY--ECQCSPGFTQGPDQTCV 508
CVD C A++ C GT C+N G+ CQ P Q
Sbjct: 611 CVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALC 670
Query: 509 -----------DVDECAEGRASCTFR-CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
D++ECA C C N GS+RC C GY A G C D+DEC
Sbjct: 671 SSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECAL 730
Query: 557 EPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTD 615
+C + C+N GSY C CP G+ QD+E C+D++EC C GVC N
Sbjct: 731 NSLLCDNGWCQNSPGSYSCSCPPGFHFW---QDTE-ICKDVDECLSSP--CVSGVCRNLA 784
Query: 616 GSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXX 675
GS+ C C G GT C+D GTC+ + RCE
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE--------------------VN 824
Query: 676 XXGHVTKAQCCCTLGAAWGSECELCPAPGSPAR 708
G +++CC TLGAAWGS CE C + AR
Sbjct: 825 LQGASLRSECCATLGAAWGSPCERCEIDPACAR 857
Score = 212 bits (517), Expect = 5e-54
Identities = 157/523 (30%), Positives = 203/523 (38%), Gaps = 74/523 (14%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAW---GAPC----------EACPPRGSPAH----TALCGE 52
CA + YLC C G+ GA C + C RG T C
Sbjct: 2177 CAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVC 2236
Query: 53 KPGEYINPVTNETKPID-ECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVD 111
PG P + E D EC P LC G C +T F+C CD G++ T C D+
Sbjct: 2237 PPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIR 2296
Query: 112 E----CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDC 167
+ + CR ++ EC C G P + C +++C HG
Sbjct: 2297 QGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGS- 2355
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN 227
GYT RDVDEC +C +G C N G++ CHC G+
Sbjct: 2356 -------------GYTAEG---RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDAT 2399
Query: 228 -NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C+D++EC + C C+NT GSF C C GY L DGR C+D+DEC H C
Sbjct: 2400 ATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNC- 2457
Query: 287 RDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVC-AGGECRNFNGGYVCECP 345
C NT G + C C G+ + C D DEC P C A G C N G + CEC
Sbjct: 2458 ---QFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECH 2514
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
G+ + C D + C RC QL C C +G +C
Sbjct: 2515 QGFTLVSSGHGCEDVNE--CDGPH---RCQHGCQNQLGGYRCSCPQGFTQHSQWAQCV-- 2567
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
D +EC + P C C NT G FRC CP G+
Sbjct: 2568 --------------------DENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGG 2607
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV 508
C D DECA C +C+NT GG+ C C G+ + CV
Sbjct: 2608 CQDVDECAGRRGPCSY-SCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 180 bits (438), Expect = 2e-44
Identities = 99/242 (40%), Positives = 122/242 (50%), Gaps = 22/242 (9%)
Query: 414 CQGGMGRPNLTQ----DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
CQ G P+ T D+DEC P C C NT GSF C CP GY+L DG +C D
Sbjct: 2390 CQAGY-TPDATATTCLDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDL 2447
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNT 527
DEC C C NT G + C+C PGFTQ Q C D DEC+ C CHNT
Sbjct: 2448 DECTSRQHNC-QFLCVNTVGAFTCRCPPGFTQH-HQACFDNDECSAQPGPCGAHGHCHNT 2505
Query: 528 AGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQ 587
GSFRC C G+ + + G C D++EC P C H C+N +G Y C CP+G+ + S Q
Sbjct: 2506 PGSFRCECHQGFTLVSSGHGCEDVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHS--Q 2562
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE------PSEDGTDCIDRRTG 641
++ C D NEC C C NT G F C C +GF+ +D +C RR G
Sbjct: 2563 WAQ--CVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRR-G 2619
Query: 642 TC 643
C
Sbjct: 2620 PC 2621
Score = 98.7 bits (235), Expect = 8e-20
Identities = 116/418 (27%), Positives = 158/418 (37%), Gaps = 56/418 (13%)
Query: 250 NTVGS-FRCECAPGYTLTADGRNCRDVDECDELPHPCGRD--GNPS-CTNTNGGYECSCG 305
N GS F C PG+ T GR+ V C CG P+ CT +G SCG
Sbjct: 58 NVCGSRFHAYCCPGWR-TFPGRSQCVVPICRRA---CGEGFCSQPNLCTCADGTLAPSCG 113
Query: 306 AG-WKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCE--CPAGWR-FDKTAAVCV--- 358
C++ C+ +C G G +C+ C G R CV
Sbjct: 114 VSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCACVYGF 173
Query: 359 -------DERKELCYDEWEAGRC-HRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
D R C+ + C H+ L + CC + G AWG CE CPA
Sbjct: 174 MGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHP-- 231
Query: 411 MRICQGGMGRPNL----TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
C+ G PN+ QD+DEC+ P +C GG CVN GSF C CP G+ L+ +C
Sbjct: 232 ---CRRGF-IPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAAC 287
Query: 467 VDADECALDPRICGNGTCSNTRGGY----ECQCSPG--FTQGPDQTCVDVDECAEGRASC 520
D A + G G C+ G+ +C C G + GP E + C
Sbjct: 288 EDYRAGACFSVLFG-GRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLC 346
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPE-G 579
R G P G G + + R+ PH GS P G
Sbjct: 347 AQRLPLLPGH-----P-GLFPGLLGFGSNGMGPPLGPARLNPH------GSDARGIPSLG 394
Query: 580 YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
++ + N DI C +LC G C+ T S+ C+C+ G+ G +CID
Sbjct: 395 PGNSNIGTATLNQTIDI--CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRG-ECID 449
Score = 98.3 bits (234), Expect = 1e-19
Identities = 46/113 (40%), Positives = 57/113 (50%), Gaps = 9/113 (7%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL--CHNT 798
D+DEC + C G F C C PG+ + C D DEC+ +P PC CHNT
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNT 2505
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
GS+ C C G+ L G C DV+EC+ H CQ C N G Y CSC G+
Sbjct: 2506 PGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHGCQNQLGGYRCSCPQGF 2557
Score = 97.9 bits (233), Expect = 1e-19
Identities = 51/124 (41%), Positives = 61/124 (49%), Gaps = 11/124 (8%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHN 797
D DECA LC APG +RC C G+ P + C DVDECA C N
Sbjct: 1362 DRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCEN 1421
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRG 855
G + C+C GYELD G NC D++EC + +C NT GSY CSC +E G
Sbjct: 1422 LPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481
Query: 856 DACV 859
CV
Sbjct: 1482 VGCV 1485
Score = 94.3 bits (224), Expect = 2e-18
Identities = 46/120 (38%), Positives = 58/120 (48%), Gaps = 10/120 (8%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ-LCH 796
DVDECA P LC G ++C C PG+ G C D+DEC++ C C
Sbjct: 1071 DVDECARDPLLCWGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCV 1130
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
N G++ C C G++ D C D++EC C C NTEGSY CSC GY D
Sbjct: 1131 NVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPD 1190
Score = 89.0 bits (211), Expect = 6e-17
Identities = 39/103 (37%), Positives = 54/103 (52%), Gaps = 4/103 (3%)
Query: 761 GRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDEDGA 817
G +RC C G+ + C D +ECA+ PP C C NT G + C+C +G++ D+
Sbjct: 2547 GGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALG 2606
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
C+DVDEC C C+NT G + C C GY + G CV
Sbjct: 2607 GCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 84.2 bits (199), Expect = 2e-15
Identities = 49/125 (39%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQ--LC 795
DVDEC P +C G F C C GY R C+DVDEC V CD C
Sbjct: 1238 DVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASC 1297
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEK 853
N GS+ C C G+ DG C D+DEC H C C N GSY C+C G+
Sbjct: 1298 LNIPGSFSCRCLPGWV--GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355
Query: 854 RGDAC 858
G C
Sbjct: 1356 DGFFC 1360
Score = 80.6 bits (190), Expect = 2e-14
Identities = 44/117 (37%), Positives = 53/117 (45%), Gaps = 12/117 (10%)
Query: 747 DVDECAAIPGLCA--------PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCH 796
D DEC+A PG C PG FRC C G+ +G C DV+EC P C C
Sbjct: 2485 DNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHGCQ 2543
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYE 852
N G Y C C G+ A C D +EC TC C NT G + C C G++
Sbjct: 2544 NQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFD 2600
Score = 73.3 bits (172), Expect = 3e-12
Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 7/95 (7%)
Query: 15 GVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIM 74
G+ TK LCC +VG AWG PCE CP + P + G N T + +DEC +
Sbjct: 202 GLVCTKALCCATVGRAWGLPCELCPAQPHPC-------RRGFIPNIHTGACQDVDECQAV 254
Query: 75 PQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
P LC+ G+C + F C C G+ ++S C D
Sbjct: 255 PGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 70.9 bits (166), Expect = 2e-11
Identities = 45/120 (37%), Positives = 58/120 (48%), Gaps = 12/120 (10%)
Query: 751 CAAIPGLCAPGRFRCVCG---PGYRP---AGEVCADVDECAVRPPPC-DQLCHNTDGSYD 803
C A P +P ++ +CG PG+ G+ D+DEC P C + +C N GS+
Sbjct: 1688 CEACPTPISPD-YQILCGNQAPGFLTDIHTGKPL-DIDECGEIPAICANGICINQIGSFR 1745
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE-KRGDACVG 860
C C G+ + C DVDEC CQQ C N GSY C C GY+ G ACVG
Sbjct: 1746 CECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVG 1805
Score = 50.4 bits (115), Expect = 3e-05
Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 32/149 (21%)
Query: 743 DVFADVDECAAIP---GLCA--PGRFRCVCGPGYR--PAGEVCADVDE--C--AVRPPPC 791
++ DVDEC + P G+C G + C CGPG R P+G C D + C ++ C
Sbjct: 762 EICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRC 821
Query: 792 DQLCHNTDGSYDCLCRTGY---------ELDE---------DGANCRDVDECERDTHTCQ 833
+ +C G E+D G C DV+ECE C
Sbjct: 822 EVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCP 881
Query: 834 Q-ICSNTEGSYECSCEDG--YEKRGDACV 859
C NT GS+ C C +G + G CV
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCV 910
Score = 48.0 bits (109), Expect = 1e-04
Identities = 57/195 (29%), Positives = 74/195 (37%), Gaps = 34/195 (17%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
GTC G C C GY T +C C G C +C+ G C C G
Sbjct: 128 GTCR----GASCLCQKGY----TGTVCGQ-PICDRG---CHNGGRCI---GPNRCACVYG 172
Query: 141 YRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRP 200
+ + P +CE D R G C +G C+ + L VC C+
Sbjct: 173 F-MGP---QCER-----DYRT---GPCFGQVGPEGCQ----HQLTGLVCTKALCCATVGR 216
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCEC 259
CE P A C GF + C DV+EC+ +C+ G C N VGSF C C
Sbjct: 217 AW-GLPCELCP-AQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRC 274
Query: 260 APGYTLTADGRNCRD 274
G+ L+ C D
Sbjct: 275 PVGHRLSDSSAACED 289
Score = 38.7 bits (86), Expect = 0.087
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGY 851
CR G+ + C+DVDEC+ CQ C N GS+ C C G+
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGH 278
>AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 728 bits (1799), Expect = 0.0
Identities = 355/869 (40%), Positives = 460/869 (52%), Gaps = 64/869 (7%)
Query: 9 SCAGAVGVPQTKYLCCCS--VGHAWGAPCEACPPRGSPAHTALCGEK-PGEYINPVTNET 65
+C + T+ +CCCS +G AW PCEACP SP + LCG + PG + T +
Sbjct: 1660 TCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKP 1719
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ 125
IDEC +P +C G C + F+C C G+ +++ C DVDEC PC+ A
Sbjct: 1720 LDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCECKPGY-- 182
C+N+PG++ C+C GY+L+P C +EC + +C HGDC +T GSY C C G+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPG-GACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQA 1838
Query: 183 TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE-GGM 241
+ + +C D+DEC R +P C NGTC+N+ G+Y C C GF N DCVD +EC G
Sbjct: 1839 SADQTLCMDIDECDR-QP-CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 242 VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
VCR G C NT GSF C C G+ LTADG+NC D +EC L C G +C N G +
Sbjct: 1897 VCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTC-LPG--TCQNLEGSFR 1953
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER 361
C C G+++ C+D DEC E P +C G C N G + C CP G+ C D R
Sbjct: 1954 CICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTR 2013
Query: 362 KELCYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMRICQGGMG 419
+ C+ +EAG+C + + CCCS+ G WG CE CP SA F +C G G
Sbjct: 2014 QSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHG 2073
Query: 420 R----PNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
+ +D++EC P VC G CVNTDGSFRCECP GY L G++CVD DEC++
Sbjct: 2074 AVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG 2133
Query: 476 PRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
CG GTC+N GG+EC C+ GF G TC D+DEC+ C FRCHNT GS+ CTC
Sbjct: 2134 -HPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTC 2192
Query: 536 PYGYAVAADGVHCRDIDECVQEPRVCPHA----CENVVGSYICKCPEGYRRTSAPQDSEN 591
P GY + DG CRD+DEC + C HA C+N++G++ C CP G R P E
Sbjct: 2193 PAGYTLREDGAMCRDVDECADGQQDC-HARGMECKNLIGTFACVCPPGMR--PLPGSGE- 2248
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGR 651
C D NEC Q DLC G C+NT GSF CDCD GF+PS T+C D R G C+ ++
Sbjct: 2249 GCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTM 2308
Query: 652 CEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDL 711
C VT+A+CCC G WG CELCP PG+ A L
Sbjct: 2309 CR------------------SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKL 2350
Query: 712 CTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCAPGRFRCVCGPGY 771
C + A + CA + + G FRC C GY
Sbjct: 2351 CP--------------HGSGYTAEGRDVDECRMLAHL--CAHGECINSLGSFRCHCQAGY 2394
Query: 772 RP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDT 829
P C D+DEC+ P PC LC NT GS+ C C GY L+EDG C+D+DEC
Sbjct: 2395 TPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQ 2454
Query: 830 HTCQQICSNTEGSYECSCEDGYEKRGDAC 858
H CQ +C NT G++ C C G+ + AC
Sbjct: 2455 HNCQFLCVNTVGAFTCRCPPGFTQHHQAC 2483
Score = 458 bits (1128), Expect = e-128
Identities = 268/748 (35%), Positives = 343/748 (45%), Gaps = 83/748 (11%)
Query: 151 EDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTLR-ENVCRDVDECSRPRPVCRNGTCE 208
+ +D C +C +G C T SYRCEC GYT C DVDEC+ C +G C
Sbjct: 407 QTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSP--CHHGDCV 464
Query: 209 NLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTA 267
N+PG Y C C GF+A P CVDV+EC G +C GRC NT GSF+C C G+ L+
Sbjct: 465 NIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSP 524
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELP 325
DG+NC D +EC C N C N +G + C C G+ L G C+D DEC + P
Sbjct: 525 DGKNCVDHNEC-ATSTMCV---NGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDEC-QTP 579
Query: 326 YVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER-KELCYDEWEAGRCHRARPLQLAR 384
+C G C N G + C+C G VCVD + CY E G C R P + +
Sbjct: 580 GICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTK 639
Query: 385 PECCCSE-GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCV 443
ECCC+ +G C+ CPA +SAEF +C G+G +D++EC + P+VC G C
Sbjct: 640 SECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCE 699
Query: 444 NTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
N GS+RC C GY G C D DECAL+ +C NG C N+ G Y C C PGF
Sbjct: 700 NLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQ 759
Query: 504 D-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP 562
D + C DVDEC + C N AGS+ C C G + G C D + ++
Sbjct: 760 DTEICKDVDECLSS-PCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQE 818
Query: 563 HACE-NVVGSYI---CKCPEGYRRTSAPQDSE--------------NACEDINECEEQED 604
CE N+ G+ + C G S + E C+D+NECE
Sbjct: 819 SRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPG 878
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXX 664
+C G C+NT GSF C+C G G C+D R C+ C
Sbjct: 879 VCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDEC------------ 926
Query: 665 XXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXX 724
G CCC++GA WG ECE CP P S LC
Sbjct: 927 --------GVTLPGKYRMDFCCCSIGAVWGVECEACPDPESLEFASLCP----------- 967
Query: 725 XXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLC-------APGRFRCVCGPGYRPAGEV 777
+ DV+EC PGLC G F C C G+ +
Sbjct: 968 ----RGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQE 1023
Query: 778 --CADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD-EDGANCRDVDECERDTHTCQ 833
C D+DEC + P C Q C NT GS++C C GYE NC DVDEC RD C+
Sbjct: 1024 RNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCR 1083
Query: 834 -QICSNTEGSYECSCEDGYE--KRGDAC 858
C+NT+GSY+C C G+E +G AC
Sbjct: 1084 GGTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Score = 442 bits (1090), Expect = e-123
Identities = 286/830 (34%), Positives = 359/830 (43%), Gaps = 101/830 (12%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+DEC P LC+ GTC +T ++C C G+E C D+DECS C QCV
Sbjct: 1072 VDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH-GQCV 1130
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
N+ GAF+C C G++ TP C D++EC Q C NT GSYRC C GY+L +
Sbjct: 1131 NVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPD 1190
Query: 188 --VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCR 244
C DVDEC VC G C N+PG + C C DGF A P+ CVDV+EC +C
Sbjct: 1191 GRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICL 1250
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
+G C NT GSF C C GY + C DVDEC+ H C D + SC N G + C C
Sbjct: 1251 HGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNC--DSHASCLNIPGSFSCRC 1308
Query: 305 GAGWKLVGRRCVDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
GW G C D DEC + C+ G+C N G Y C C G+ D DE E
Sbjct: 1309 LPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAE 1368
Query: 364 --------LCYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMR- 412
C + RC C + A G C + R
Sbjct: 1369 NVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRC 1428
Query: 413 ICQGGM----GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
IC GG G N T D++EC P C+ G C+NT GS+ C CP + L P G+ CVD
Sbjct: 1429 ICNGGYELDRGGGNCT-DINEC-ADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVD 1486
Query: 469 --ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRA---SCTFR 523
A C L+ G+ G C G C C+ GRA C
Sbjct: 1487 TRAGNCFLETHDRGDS-------GISCSAEIGVGVTRASCC-----CSLGRAWGNPCELC 1534
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHC--RDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
+R CP G + + DIDEC + P +C C N GS+ C+CP GY
Sbjct: 1535 PMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGY 1594
Query: 581 RRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRT 640
+ + CEDI+EC +C G C NT G++ C C A + G +C+D R
Sbjct: 1595 HLS----EHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRK 1650
Query: 641 GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCT--LGAAWGSECE 698
C+R +G C+ E +VT+ CCC+ +G AW CE
Sbjct: 1651 SVCFRH-YNGTCQNELAF--------------------NVTRKMCCCSYNIGQAWNRPCE 1689
Query: 699 LCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLC 758
CP P SP LC N P D+DEC IP +C
Sbjct: 1690 ACPTPISPDYQILCG--NQAPGFLTDIHTGKP---------------LDIDECGEIPAIC 1732
Query: 759 AP-------GRFRCVCGPG--YRPAGEVCADVDECAVRPPPCDQL--CHNTDGSYDCLCR 807
A G FRC C G Y C DVDEC R PC Q C N GSY C C
Sbjct: 1733 ANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCT 1792
Query: 808 TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
GY+L GA C +EC + C C +TEGSY C C G++ D
Sbjct: 1793 RGYKLSPGGA-CVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASAD 1841
Score = 430 bits (1059), Expect = e-119
Identities = 232/592 (39%), Positives = 290/592 (48%), Gaps = 47/592 (7%)
Query: 1 MEWNEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
+ W+E++ C + CCCS+G WG CEACP S +LC G
Sbjct: 919 LRWDEDE--CGVTLPGKYRMDFCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRD 976
Query: 61 VTNET---KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGR 117
+ K ++EC + P LC GTC +T F C C G+ D C D+DEC
Sbjct: 977 FLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISP 1036
Query: 118 PPCRGMAQCVNLPGAFECRCPPGYRLTPSL-DECEDVDECG-DQRICDHGDCRNTIGSYR 175
C G CVN PG+FEC C PGY L C DVDEC D +C G C NT GSY+
Sbjct: 1037 DLC-GQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYK 1095
Query: 176 CECKPGY--TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVD 232
C+C PG+ T + C D+DECS +C +G C N+ GA+ C C GF++ P+ CVD
Sbjct: 1096 CQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVD 1155
Query: 233 VNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
+NECR C + C NT GS+RC C GY+L DGR C DVDEC+E P C +
Sbjct: 1156 INECRVQNGGC-DVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQG---H 1211
Query: 293 CTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRF 350
CTN GG+ C C G+ R CVD DEC P++C G+C N G +VC C G+
Sbjct: 1212 CTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMV 1271
Query: 351 DKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
K A C D DE E G H C A+ C P S
Sbjct: 1272 RKGATGCSD------VDECEVGG-HN------------CDSHAS----CLNIPGSFSC-- 1306
Query: 411 MRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
R G +G DLDEC + C G C+N GS+RC C G+ A DG C D
Sbjct: 1307 -RCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCEDR 1363
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTA 528
DECA + +C NG C N GGY C+C GF D + C DVDECA+G C N
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLP 1423
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGY 580
G FRC C GY + G +C DI+EC C N GSY+C CP+ +
Sbjct: 1424 GMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDF 1475
Score = 411 bits (1011), Expect = e-114
Identities = 300/917 (32%), Positives = 374/917 (40%), Gaps = 98/917 (10%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPID 69
C VG Q C V +PC P T C PG P +D
Sbjct: 433 CECNVGYTQDVRGECIDVDECTSSPCHHGDCVNIPG-TYHCRCYPGFQATPTRQACVDVD 491
Query: 70 ECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
EC + LC G C +T FQC C+ G+E C D +EC+ G+ C+N
Sbjct: 492 ECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGV--CLNE 549
Query: 130 PGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN-- 187
G+F C C PG+ L P C D+DEC IC +G C NT GS+RC+C G + +
Sbjct: 550 DGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGR 609
Query: 188 VCRDVD------------ECSRPRP--VCRNGTCENLPG------AYLCHCDDG--FKA- 224
VC D C+RP P V ++ C P LC + F+A
Sbjct: 610 VCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQAL 669
Query: 225 -----GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECD 279
G D D+NEC VC NG C N GS+RC C GY A G++C DVDEC
Sbjct: 670 CSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECA 729
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFN 337
C N C N+ G Y CSC G+ C D DEC P C G CRN
Sbjct: 730 LNSLLCD---NGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLA 784
Query: 338 GGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGR 397
G Y C+C G R D + C+D K C+ + + RC R ECC + GAAWG
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGS 844
Query: 398 YCERCPAPDSAEFMRICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPD 455
CERC E C G R D++EC P VC GRCVNT GSFRCECP+
Sbjct: 845 PCERC------EIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPE 898
Query: 456 GYVLAPDGLSCVDA--DECAL--DPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDV 510
G +L G CVD + C L D CG R + C CS G G + + C D
Sbjct: 899 GLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDF-CCCSIGAVWGVECEACPD- 956
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH-ACENVV 569
E E + C + F P+ +D++EC P +C H C N V
Sbjct: 957 PESLEFASLCPRGLGFASRDFLSGRPF----------YKDVNECKVFPGLCTHGTCRNTV 1006
Query: 570 GSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP- 628
GS+ C C G+ A E C DI+EC DLC G C+NT GSF C+C G+E
Sbjct: 1007 GSFHCACAGGF----ALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESG 1062
Query: 629 ----------SEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXG 678
E D + R GTC + S +C+ G
Sbjct: 1063 FMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDG 1122
Query: 679 HVTKAQCCCTLGAAWGS-ECELCPAPGSPARLDL--CTAVNLTPXXXXXXXXXXXXXXXX 735
QC +GA S P +D+ C N
Sbjct: 1123 LCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCG 1182
Query: 736 XXXXXXLD--VFADVDECAAIPGLC-------APGRFRCVCGPGY--RPAGEVCADVDEC 784
D ADVDEC P +C PG RC+C G+ P C DVDEC
Sbjct: 1183 QGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDEC 1242
Query: 785 AVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEG 841
+ P C C NT GS+ C C+ GY + + C DVDECE H C C N G
Sbjct: 1243 DLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPG 1302
Query: 842 SYECSCEDGYEKRGDAC 858
S+ C C G+ G C
Sbjct: 1303 SFSCRCLPGWVGDGFEC 1319
Score = 405 bits (996), Expect = e-112
Identities = 224/611 (36%), Positives = 293/611 (47%), Gaps = 53/611 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDE--------------- 112
IDEC P LC GTC ++P FQC C G+ + H C D +
Sbjct: 1970 IDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVP 2029
Query: 113 ---------CSWGRPPCRGMAQ-CVNLP----GAFECRCPPGYRLTPSLDEC-EDVDECG 157
C + P G C P AF+ CP G+ P D+ EDV+EC
Sbjct: 2030 KAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECA 2089
Query: 158 DQR-ICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAY 214
+ +C +G C NT GS+RCEC GY+L C D DECS P C GTC N+ G +
Sbjct: 2090 ENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP-CGQGTCTNVIGGF 2148
Query: 215 LCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRD 274
C C DGF+ G C D++EC ++C RC NT GS+ C C GYTL DG CRD
Sbjct: 2149 ECACADGFEPGLMMTCEDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Query: 275 VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV---GRRCVDRDECKELPYVCAGG 331
VDEC + C G C N G + C C G + + G C D +EC P +C G
Sbjct: 2208 VDECADGQQDCHARGM-ECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNG 2266
Query: 332 ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLA--RPECCC 389
C N G + C+C G++ T C D R+ C+ E C A R ECCC
Sbjct: 2267 RCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCC 2326
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
G WG CE CP P ++ + ++C G G +D+DECR+ +C G C+N+ GSF
Sbjct: 2327 GGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSF 2386
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCV 508
RC C GY +C+D DEC+ P+ C C NT+G + C C G+ D +TC
Sbjct: 2387 RCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCK 2445
Query: 509 DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC-PHA-CE 566
D+DEC + +C F C NT G+F C CP G+ C D DEC +P C H C
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQA--CFDNDECSAQPGPCGAHGHCH 2503
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
N GS+ C+C +G+ S S + CED+NEC+ C G C N G + C C GF
Sbjct: 2504 NTPGSFRCECHQGFTLVS----SGHGCEDVNECDGPH-RCQHG-CQNQLGGYRCSCPQGF 2557
Query: 627 EPSEDGTDCID 637
C+D
Sbjct: 2558 TQHSQWAQCVD 2568
Score = 395 bits (972), Expect = e-109
Identities = 287/876 (32%), Positives = 377/876 (43%), Gaps = 134/876 (15%)
Query: 21 YLCCCSVGHAW---GAPCEACPPRGSPAH--TALCGEKPGEYIN--PVTNETKP--IDEC 71
+ C C+ G+ G C P + +C PG Y+ P E P +
Sbjct: 1426 FRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCV 1485
Query: 72 DIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG 131
D C T +G C + G S C + +WG P C + N
Sbjct: 1486 DTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCC-SLGR-AWGNP-CE-LCPMANTT- 1540
Query: 132 AFECRCPPGYRLTPSLDEC--EDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTLREN- 187
+ CP G P+ ED+DEC + +C GDC NT GS++CEC PGY L E+
Sbjct: 1541 EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHT 1600
Query: 188 -VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF-KAGPNNDCVDVNECREGGMVC-- 243
+C D+DECS +C GTC N G Y C C + + N+C+D+ + VC
Sbjct: 1601 RICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKS-----VCFR 1655
Query: 244 -RNGRCRNTVGS--FRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGY 300
NG C+N + R C Y + C+ P P D C N G+
Sbjct: 1656 HYNGTCQNELAFNVTRKMCCCSYNIGQAWNR-----PCEACPTPISPDYQILCGNQAPGF 1710
Query: 301 ECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
G L D DEC E+P +CA G C N G + CECPAG+ ++ C D
Sbjct: 1711 LTDIHTGKPL------DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACED- 1763
Query: 361 RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG--M 418
DE + R P Q +C G+ RC ++ GG +
Sbjct: 1764 -----VDECGS----RESPCQ-QNADCINIPGSY------RCKCTRG---YKLSPGGACV 1804
Query: 419 GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRI 478
GR +ECR P+VC G C++T+GS+ C C G+ + D C+D DEC P
Sbjct: 1805 GR-------NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQP-- 1855
Query: 479 CGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAE--GRASCTF-RCHNTAGSFRCTC 535
CGNGTC N G Y C C PGF + CVD DEC G+ C F C NTAGSF C C
Sbjct: 1856 CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQV-CRFGHCLNTAGSFHCLC 1914
Query: 536 PYGYAVAADGVHCRDIDECVQEPRVC-PHACENVVGSYICKCPEGYRRTSAPQDSENACE 594
G+ + ADG +C D +EC+ C P C+N+ GS+ C CP G+ Q + C
Sbjct: 1915 QDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGF------QVQSDHCI 1968
Query: 595 DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEP 654
DI+EC E+ +LC G C N+ GSF C C GF S++G C D R C+ +G+C
Sbjct: 1969 DIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSV 2028
Query: 655 EXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTL--GAAWGSECELCPAPGSPARLDLC 712
+ TK +CCC+ G WG CELCP GS A +LC
Sbjct: 2029 PKAF--------------------NTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELC 2068
Query: 713 TAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCA-------PGRFRC 765
P D DV+ECA PG+C G FRC
Sbjct: 2069 ------PFGHGAVPGPD-------------DSREDVNECAENPGVCTNGVCVNTDGSFRC 2109
Query: 766 VCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
C GY G C D DEC+V P C N G ++C C G+E C D+D
Sbjct: 2110 ECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLM-MTCEDID 2168
Query: 824 ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 859
EC + C C NTEGSY C+C GY R D +
Sbjct: 2169 ECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAM 2204
Score = 380 bits (935), Expect = e-104
Identities = 219/596 (36%), Positives = 284/596 (47%), Gaps = 43/596 (7%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
CG+ G + P +DEC+ P++C G C + P G +C C G+ C D
Sbjct: 1181 CGQ--GYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVD 1238
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC--GDQRICDHGDC 167
VDEC C C N G+F C C GY + C DVDEC G H C
Sbjct: 1239 VDECDLNPHICLH-GDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASC 1297
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGP 226
N GS+ C C PG+ C D+DEC C G C N+PG+Y C C GF AG
Sbjct: 1298 LNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF-AGD 1356
Query: 227 NNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C D +EC E +C NG+C N G +RCEC G+ T D R C+DVDEC + + C
Sbjct: 1357 GFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ-GNLCA 1415
Query: 287 RDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
SC N G + C C G++L G C D +EC + P C G C N G Y+C C
Sbjct: 1416 FG---SCENLPGMFRCICNGGYELDRGGGNCTDINECAD-PVNCINGVCINTPGSYLCSC 1471
Query: 345 PAGWRFDKTAAVCVDERKELCY----DEWEAG-RCHRARPLQLARPECCCSEGAAWGRYC 399
P + + + CVD R C+ D ++G C + + R CCCS G AWG C
Sbjct: 1472 PQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPC 1531
Query: 400 ERCPAPDSAEFMRICQGGMG-RPN----LTQDLDECRVRPDVCVGGRCVNTDGSFRCECP 454
E CP ++ E+ +C GG G +PN + +D+DEC+ P +C GG CVNT GSF+CECP
Sbjct: 1532 ELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECP 1591
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ-GPDQTCVDVDEC 513
GY L+ C D DEC+ ICG GTC NT G Y C C + Q C+D+
Sbjct: 1592 PGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDM--- 1648
Query: 514 AEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVG-S 571
R S FR +N C + V C +I + P C AC +
Sbjct: 1649 ---RKSVCFRHYNGT----CQNELAFNVTRKMCCCSYNIGQAWNRP--C-EACPTPISPD 1698
Query: 572 YICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
Y C G + D DI+EC E +C+ G+CIN GSF C+C AGF
Sbjct: 1699 YQILC--GNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGF 1752
Score = 372 bits (914), Expect = e-102
Identities = 242/661 (36%), Positives = 302/661 (45%), Gaps = 88/661 (13%)
Query: 11 AGAVGVPQ----TKYLCCCSV--GHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNE 64
AG VP+ TK CCCS G WG PCE CP GS A LC G P +
Sbjct: 2023 AGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGP-DDS 2081
Query: 65 TKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+ ++EC P +C G C +T F+C C GY D T C D DECS G P C G
Sbjct: 2082 REDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP-C-GQG 2139
Query: 125 QCVNLPGAFECRCPPGYRLTPSLD-ECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYT 183
C N+ G FEC C G+ P L CED+DEC + C NT GSY C C GYT
Sbjct: 2140 TCTNVIGGFECACADGFE--PGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYT 2197
Query: 184 LREN--VCRDVDECSRPRPVC--RNGTCENLPGAYLCHCDDGFKA--GPNNDCVDVNECR 237
LRE+ +CRDVDEC+ + C R C+NL G + C C G + G C D NEC
Sbjct: 2198 LREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECH 2257
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE-----------CDELPHP-- 284
+C NGRC NT GSFRC+C G+ + C D+ + C L
Sbjct: 2258 AQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSE 2317
Query: 285 --------CG--RDGNPSCTNT----NGGYE--CSCGAGWKLVGRRCVDRDECKELPYVC 328
CG R P C Y C G+G+ GR D DEC+ L ++C
Sbjct: 2318 AVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGR---DVDECRMLAHLC 2374
Query: 329 AGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECC 388
A GEC N G + C C AG+ D TA C+D DE C Q+ +P C
Sbjct: 2375 AHGECINSLGSFRCHCQAGYTPDATATTCLD------MDE-----CS-----QVPKP-CT 2417
Query: 389 CSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGS 448
G + CP E + G +DLDEC R C CVNT G+
Sbjct: 2418 FLCKNTKGSFLCSCPRGYLLE-----EDG----RTCKDLDECTSRQHNCQF-LCVNTVGA 2467
Query: 449 FRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQ-GPDQT 506
F C CP G+ +C D DEC+ P CG +G C NT G + C+C GFT
Sbjct: 2468 FTCRCPPGFTQHHQ--ACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHG 2525
Query: 507 CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-C 565
C DV+EC +G C C N G +RC+CP G+ + C D +EC P C A C
Sbjct: 2526 CEDVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASC 2584
Query: 566 ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
N +G + C CP G+ A C+D++EC + CS C NT G FLC C G
Sbjct: 2585 RNTLGGFRCVCPSGFDFDQAL----GGCQDVDECAGRRGPCSYS-CANTPGGFLCGCPQG 2639
Query: 626 F 626
+
Sbjct: 2640 Y 2640
Score = 356 bits (876), Expect = 2e-97
Identities = 213/603 (35%), Positives = 278/603 (46%), Gaps = 41/603 (6%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC LC G C + P G++C C+ G++ C+DVDEC+ G G C N
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFG--SCEN 1421
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENV 188
LPG F C C GY L C D++EC D C +G C NT GSY C C + L +
Sbjct: 1422 LPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481
Query: 189 CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC 248
VD + C T + C + G + C + R G C
Sbjct: 1482 VGCVDTRAGN---CFLETHDRGDSGISCSAEIGVGVTRASCCCSLG--RAWGNPCELCPM 1536
Query: 249 RNTVGSFRCECAPGYTLTADGRNC--RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
NT +R C G + D+DEC ELP C + G+ C NT G ++C C
Sbjct: 1537 ANTT-EYRTLCPGGEGFQPNRITVILEDIDECQELPGLC-QGGD--CVNTFGSFQCECPP 1592
Query: 307 GWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKEL 364
G+ L R C D DEC +C G C N G Y C CPA + C+D RK +
Sbjct: 1593 GYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSV 1652
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMRICQGGMGRPN 422
C+ + G C + R CCCS G AW R CE CP P S ++ +C G
Sbjct: 1653 CFRHYN-GTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILC-GNQAPGF 1710
Query: 423 LTQ-------DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
LT D+DEC P +C G C+N GSFRCECP G+ L+C D DEC
Sbjct: 1711 LTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSR 1770
Query: 476 PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRC 533
C N C N G Y C+C+ G+ P CV +EC E C+ C +T GS+ C
Sbjct: 1771 ESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMC 1830
Query: 534 TCPYGYAVAADGVHCRDIDECVQEPRVCPH-ACENVVGSYICKCPEGYRRTSAPQDSENA 592
C G+ +AD C DIDEC ++P C + C+N++GSY C C G+ T
Sbjct: 1831 LCHRGFQASADQTLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGFVVT-----HNGD 1883
Query: 593 CEDINECEE-QEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGR 651
C D +EC +C G C+NT GSF C C GFE + DG +C+D T C ++G
Sbjct: 1884 CVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVD--TNECLS--LAGT 1939
Query: 652 CEP 654
C P
Sbjct: 1940 CLP 1942
Score = 343 bits (842), Expect = 2e-93
Identities = 209/655 (31%), Positives = 294/655 (44%), Gaps = 59/655 (9%)
Query: 9 SCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPI 68
SC+ +GV T+ CCCS+G AWG PCE CP + + LC G N +T + I
Sbjct: 1505 SCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDI 1564
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC +P LC+ G C +T FQC C GY + +C D+DECS C G C N
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGTCYN 1623
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTI--GSYRCECKPGYTLRE 186
G + C CP Y + C D+ + R +G C+N + R C Y + +
Sbjct: 1624 TLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHY-NGTCQNELAFNVTRKMCCCSYNIGQ 1682
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
R + C P C N +L G +D++EC E +C NG
Sbjct: 1683 AWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTG-------KPLDIDECGEIPAICANG 1735
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
C N +GSFRCEC G+ + C DVDEC PC + N C N G Y C C
Sbjct: 1736 ICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQ--NADCINIPGSYRCKCTR 1793
Query: 307 GWKL-VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
G+KL G CV R+EC+E+P VC+ G+C + G Y+C C G++ +C+D
Sbjct: 1794 GYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMD------ 1847
Query: 366 YDEWEAGRCHRARPLQ-LARPECCCSEG----------------AAWGRYCERCPAPDSA 408
DE + C + C C G G+ C ++A
Sbjct: 1848 IDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTA 1907
Query: 409 -EFMRICQGGM---GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
F +CQ G D +EC C+ G C N +GSFRC CP G+ + D
Sbjct: 1908 GSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSD-- 1965
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
C+D DEC+ +P +C GTC+N+ G ++C C PGF + C + R S C
Sbjct: 1966 HCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG-----HRCFDTRQSF---C 2017
Query: 525 HNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEP-RVCPHACENVVGSYICKCPEGYRR 582
+ +C+ P + C + E +P +CP + ++ CP G+
Sbjct: 2018 FTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCP---QEGSAAFQELCPFGHGA 2074
Query: 583 TSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
P DS ED+NEC E +C+ GVC+NTDGSF C+C G+ G +C+D
Sbjct: 2075 VPGPDDSR---EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVD 2126
Score = 337 bits (828), Expect = 1e-91
Identities = 216/646 (33%), Positives = 295/646 (45%), Gaps = 65/646 (10%)
Query: 23 CCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGT 82
CC ++G AWG+PCE C PA G VT + ++EC+ P +C G
Sbjct: 834 CCATLGAAWGSPCERCEI--DPACARGFARMTG-----VTCDD--VNECESFPGVCPNGR 884
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDV--DEC--SWGRPPCRGMAQCVNLPGAFE---C 135
C +T F+C C G D + LC DV + C W C V LPG + C
Sbjct: 885 CVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECG-----VTLPGKYRMDFC 939
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDEC 195
C G + C D + +C G +G + G +DV+EC
Sbjct: 940 CCSIGAVWGVECEACPDPESLEFASLCPRG-----LGFASRDFLSGRPFY----KDVNEC 990
Query: 196 SRPRPVCRNGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRNGRCRNTVGS 254
+C +GTC N G++ C C GF +C D++ECR +C G C NT GS
Sbjct: 991 KVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGS 1050
Query: 255 FRCECAPGYTLTAD-GRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV-- 311
F CEC PGY +NC DVDEC P C R G +CTNT+G Y+C C G +L
Sbjct: 1051 FECECFPGYESGFMLMKNCMDVDECARDPLLC-RGG--TCTNTDGSYKCQCPPGHELTAK 1107
Query: 312 GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK--------- 362
G C D DEC +C G+C N G + C C AG++ CVD +
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCD 1167
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCS---EGAAWGRYCERCPAPDSAEFMR-ICQGG- 417
C + + RC + L C+ E R C++ + R +C G
Sbjct: 1168 VHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGF 1227
Query: 418 MGRPNLTQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
M P++ D+DEC + P +C+ G C NT GSF C C GY++ C D DEC +
Sbjct: 1228 MATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVG 1287
Query: 476 PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFR 532
C + +C N G + C+C PG+ G C D+DEC C+ R C N GS+R
Sbjct: 1288 GHNCDSHASCLNIPGSFSCRCLPGWV-GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYR 1346
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSEN 591
CTC G+A DG C D DEC + +C + C N G Y C+C G+ P +
Sbjct: 1347 CTCRQGFA--GDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFD----PTEDHR 1400
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
AC+D++EC Q +LC+ G C N G F C C+ G+E G +C D
Sbjct: 1401 ACQDVDEC-AQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTD 1445
Score = 329 bits (808), Expect = 3e-89
Identities = 239/714 (33%), Positives = 308/714 (43%), Gaps = 111/714 (15%)
Query: 21 YLCCCSVGHAWGAPCEACPPRGSPAHTAL------CGEKPGEYINPV---------TNET 65
Y C C++G+ GA + C A +L C PG Y T
Sbjct: 705 YRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEIC 764
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS-WGR---PPCR 121
K +DEC P C G C + + C C G D + C D + + W + C
Sbjct: 765 KDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE 822
Query: 122 GMAQ--------CVNLPGAF-----ECR----CPPGYRLTPSLDECEDVDECGD-QRICD 163
Q C L A+ C C G+ + C+DV+EC +C
Sbjct: 823 VNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVT-CDDVNECESFPGVCP 881
Query: 164 HGDCRNTIGSYRCECKPGYTLREN--VCRDV-----------DECSRPRP--------VC 202
+G C NT GS+RCEC G L + +C DV DEC P C
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDFCCC 941
Query: 203 RNGT-----CENLPG------AYLCHCDDGFKA----GPNNDCVDVNECREGGMVCRNGR 247
G CE P A LC GF + DVNEC+ +C +G
Sbjct: 942 SIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT 1001
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
CRNTVGSF C CA G+ L A RNC D+DEC P CG+ +C NT G +EC C G
Sbjct: 1002 CRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG---TCVNTPGSFECECFPG 1058
Query: 308 WK---LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKE 363
++ ++ + C+D DEC P +C GG C N +G Y C+CP G C D +
Sbjct: 1059 YESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECS 1118
Query: 364 L---------CYDEWEAGRC--HRARPLQLARPECC-CSEGAAWGRYCE-RCPAPDSAEF 410
L C + A +C H R C +E C+ C + +
Sbjct: 1119 LSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYR 1178
Query: 411 MRICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
QG P+ D+DEC P VC G C N G RC C DG++ PD +CVD
Sbjct: 1179 CSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVD 1238
Query: 469 ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFR--CH 525
DEC L+P IC +G C NT+G + C C G+ T C DVDEC G +C C
Sbjct: 1239 VDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCL 1298
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECV-QEPRVCPHA-CENVVGSYICKCPEGYRRT 583
N GSF C C G+ DG C D+DECV QE R P C NV GSY C C +G+
Sbjct: 1299 NIPGSFSCRCLPGWV--GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGD 1356
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
CED +EC E DLC G C+N G + C+C+ GF+P+ED C D
Sbjct: 1357 GF------FCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 290 bits (711), Expect = 2e-77
Identities = 192/556 (34%), Positives = 250/556 (44%), Gaps = 83/556 (14%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC + C GTC + GF+C C G+E C D+DECS C +C N
Sbjct: 2128 DECSV-GHPCGQGTCTNVIGGFECACADGFE-PGLMMTCEDIDECSLNPLLCA--FRCHN 2183
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICD-HG-DCRNTIGSYRCECKPGYTLR 185
G++ C CP GY L C DVDEC D Q+ C G +C+N IG++ C C PG
Sbjct: 2184 TEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPL 2243
Query: 186 ENV---CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF------------KAGP---- 226
C D +EC +C NG C N G++ C CD+GF + GP
Sbjct: 2244 PGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAE 2303
Query: 227 -----------NNDCVDVNECREGGMVCRNGRCRNT----VGSFRCECAPGYTLTADGRN 271
+++ V EC GG RC ++R C G TA+GR
Sbjct: 2304 VLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGR- 2362
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK--LVGRRCVDRDECKELPYVCA 329
DVDEC L H C C N+ G + C C AG+ C+D DEC ++P C
Sbjct: 2363 --DVDECRMLAHLCAHG---ECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCT 2417
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C+N G ++C CP G+ ++ C D DE + R H + L C
Sbjct: 2418 F-LCKNTKGSFLCSCPRGYLLEEDGRTCKD------LDECTS-RQHNCQFL------CVN 2463
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGS 448
+ GA + RCP P + + C D DEC +P C G C NT GS
Sbjct: 2464 TVGA----FTCRCP-PGFTQHHQACF----------DNDECSAQPGPCGAHGHCHNTPGS 2508
Query: 449 FRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-C 507
FRCEC G+ L G C D +EC P C +G C N GGY C C GFTQ C
Sbjct: 2509 FRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQC 2566
Query: 508 VDVDECAEGRASC-TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
VD +ECA +C + C NT G FRC CP G+ C+D+DEC C ++C
Sbjct: 2567 VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYSCA 2626
Query: 567 NVVGSYICKCPEGYRR 582
N G ++C CP+GY R
Sbjct: 2627 NTPGGFLCGCPQGYFR 2642
Score = 290 bits (711), Expect = 2e-77
Identities = 195/525 (37%), Positives = 244/525 (46%), Gaps = 87/525 (16%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC--RGMAQ 125
IDEC + P LC CH+T + C C GY +CRDVDEC+ G+ C RGM +
Sbjct: 2167 IDECSLNPLLCA-FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGM-E 2224
Query: 126 CVNLPGAFECRCPPGYRLTPSLDE-CEDVDECGDQR-ICDHGDCRNTIGSYRCECKPGY- 182
C NL G F C CPPG R P E C D +EC Q +C +G C NT GS+RC+C G+
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 183 ---TLRE---------------NVCRDVDECS----RPRPVCRNGT-----CE--NLPG- 212
TL E +CR + S R C G CE LPG
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGT 2344
Query: 213 -AYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRN 271
AY C G +G + DV+ECR +C +G C N++GSFRC C GYT A
Sbjct: 2345 SAYRKLCPHG--SGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATT 2402
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCA 329
C D+DEC ++P PC C NT G + CSC G+ L GR C D DEC + C
Sbjct: 2403 CLDMDECSQVPKPC----TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQ 2458
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C N G + C CP G+ + + C+D E A+P C
Sbjct: 2459 F-LCVNTVGAFTCRCPPGFT----------QHHQACFDNDECS----------AQPGPCG 2497
Query: 390 SEGAAWGRYCERCPAPDSAEFMR---ICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTD 446
+ G +C P E + + G G +D++EC P C G C N
Sbjct: 2498 AHG-----HCHNTPGSFRCECHQGFTLVSSGHG----CEDVNECD-GPHRCQHG-CQNQL 2546
Query: 447 GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT 506
G +RC CP G+ CVD +ECAL P CG+ +C NT GG+ C C GF DQ
Sbjct: 2547 GGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDF--DQA 2604
Query: 507 ---CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC 548
C DVDECA R C++ C NT G F C CP GY A G HC
Sbjct: 2605 LGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG-HC 2648
Score = 287 bits (704), Expect = 1e-76
Identities = 241/778 (30%), Positives = 309/778 (39%), Gaps = 109/778 (14%)
Query: 122 GMAQCVNLPGAFECR--CPPGYRLTPSLDECED---VDECGDQRICDHG-DCRN--TIGS 173
G +QCV +P CR C G+ P+L C D CG R C N T
Sbjct: 77 GRSQCV-VP---ICRRACGEGFCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMNGGTCRG 132
Query: 174 YRCECKPGYTLRENVCRDVDECSRPRPVCRNG-------TCENLPGAYLCHCDDGFKAGP 226
C C+ GYT VC C R C NG C + G C+ ++ GP
Sbjct: 133 ASCLCQKGYT--GTVCGQ-PICDRG---CHNGGRCIGPNRCACVYGFMGPQCERDYRTGP 186
Query: 227 NNDCVDVNECREG--GMVCRNGRCRNTVG---SFRCECAP--------GYTLTADGRNCR 273
V C+ G+VC C TVG CE P G+ C+
Sbjct: 187 CFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQ 246
Query: 274 DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPY-VCAGGE 332
DVDEC +P C G SC N G + C C G +L D + V GG
Sbjct: 247 DVDECQAVPGLC--QGG-SCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGR 303
Query: 333 CRNFNGGYV----CECPAG--WRFDKTAAVCV----DERKELCYDEWEAGRCHRAR-PLQ 381
C G+ C C G W +C +E ++LC H P
Sbjct: 304 CAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGL 363
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
L R + +G L Q +D CR ++C+ GR
Sbjct: 364 LGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGR 423
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
C+ T S+RCEC GY G C+D DEC P C +G C N G Y C+C PGF
Sbjct: 424 CLPTPSSYRCECNVGYTQDVRG-ECIDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQA 480
Query: 502 GPD-QTCVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPR 559
P Q CVDVDEC C RC NT GSF+C C G+ ++ DG +C D +EC
Sbjct: 481 TPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 560 VCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFL 619
C N GS+ C C G+ AP + C DI+EC + +C G C NT+GSF
Sbjct: 541 CVNGVCLNEDGSFSCLCKPGF--LLAP--GGHYCMDIDEC-QTPGICVNGHCTNTEGSFR 595
Query: 620 CDCDAGFEPSEDGTDCIDRRT-GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXG 678
C C G DG C+D TCY ++ G C G
Sbjct: 596 CQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSC--------------------ARPFPG 635
Query: 679 HVTKAQCCC-TLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXX 737
VTK++CCC +G C+LCPA S LC++
Sbjct: 636 TVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSS----------------GLGITTD 679
Query: 738 XXXXLDVFADVDECAAIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ 793
+ D + CA G+C G +RCVC GY +G+ C DVDECA+ CD
Sbjct: 680 GRDINECALDPEVCA--NGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDN 737
Query: 794 -LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
C N+ GSY C C G+ +D C+DVDEC + +C N GSY C C G
Sbjct: 738 GWCQNSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPG 794
Score = 263 bits (644), Expect = 2e-69
Identities = 204/618 (33%), Positives = 258/618 (41%), Gaps = 70/618 (11%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGA-PC-EACPPRGSPAHTALCGEK-------PGEYINP 60
CAG + T+ CCC G W A P E CPPRGS LC ++ PG +
Sbjct: 304 CAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGL 363
Query: 61 VTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+ + + + P P H + G + T+ L + +D C C
Sbjct: 364 LGFGSNGMGP-PLGPARLNP---HGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLC 419
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
+C+ P ++ C C GY EC DVDEC C HGDC N G+Y C C P
Sbjct: 420 LN-GRCLPTPSSYRCECNVGY-TQDVRGECIDVDECTSSP-CHHGDCVNIPGTYHCRCYP 476
Query: 181 GY--TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECR 237
G+ T C DVDEC +C G C N G++ C C+ GF+ P+ +CVD NEC
Sbjct: 477 GFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECA 536
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTN 297
M C NG C N GSF C C PG+ L G C D+DEC + P C N CTNT
Sbjct: 537 TSTM-CVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDEC-QTPGIC---VNGHCTNTE 591
Query: 298 GGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGEC-RNFNGGYV---CECP-AGWRF 350
G + C C G + GR CVD G C R F G C C F
Sbjct: 592 GSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGF 651
Query: 351 DKTAAVC----VDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPD 406
+ +C E + LC R PE C + R RC
Sbjct: 652 GEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNL 711
Query: 407 SAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
E G G+ D+DEC + +C G C N+ GS+ C CP G+ D C
Sbjct: 712 GYE-----AGASGKD--CTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEIC 764
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDE--C----AEGR-- 517
D DEC P C +G C N G Y C+C PG P T C+D + C E R
Sbjct: 765 KDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE 822
Query: 518 -----ASCTFRCHNTAGSF------RC----TCPYGYAVAADGVHCRDIDECVQEPRVCP 562
AS C T G+ RC C G+A GV C D++EC P VCP
Sbjct: 823 VNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFA-RMTGVTCDDVNECESFPGVCP 881
Query: 563 HA-CENVVGSYICKCPEG 579
+ C N GS+ C+CPEG
Sbjct: 882 NGRCVNTAGSFRCECPEG 899
Score = 256 bits (627), Expect = 2e-67
Identities = 221/687 (32%), Positives = 282/687 (41%), Gaps = 129/687 (18%)
Query: 40 PRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYE 99
P GS A + PG + ID C LC G C TP+ ++C C+ GY
Sbjct: 382 PHGSDAR-GIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYT 440
Query: 100 HDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GD 158
D C DVDEC+ PC CVN+PG + CRC PG++ TP+ C DVDEC
Sbjct: 441 QDVRGE-CIDVDECT--SSPCH-HGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVS 496
Query: 159 QRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLC 216
+C G C NT GS++C C G+ L + C D +EC+ +C NG C N G++ C
Sbjct: 497 GGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECA-TSTMCVNGVCLNEDGSFSC 555
Query: 217 HCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV 275
C GF P C+D++EC+ G +C NG C NT GSFRC+C G + DGR C D
Sbjct: 556 LCKPGFLLAPGGHYCMDIDECQTPG-ICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDT 614
Query: 276 ---DEC--------DELPHP---------CGRD----GNPS--CTNTNGG-YECSCGAGW 308
C P P C G P C N ++ C +G
Sbjct: 615 HVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGL 674
Query: 309 KLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCY 366
+ GR D +EC P VCA G C N G Y C C G+ + C D
Sbjct: 675 GITTDGR---DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTD------V 725
Query: 367 DEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM---GRPNL 423
DE C A C G +C+ P S C G +
Sbjct: 726 DE-----C--------ALNSLLCDNG-----WCQNSPGSYSCS----CPPGFHFWQDTEI 763
Query: 424 TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA---------DECAL 474
+D+DEC P CV G C N GS+ C+C G L P G C+D+ E
Sbjct: 764 CKDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRC 821
Query: 475 DPRICG---NGTCSNTRG---GYECQ-------CSPGFTQGPDQTCVDVDECAEGRASC- 520
+ + G C T G G C+ C+ GF + TC DV+EC C
Sbjct: 822 EVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCP 881
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRDI-----------DEC-VQEP-RVCPHACEN 567
RC NTAGSFRC CP G + A G C D+ DEC V P + C
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDFCCC 941
Query: 568 VVGSY------ICKCPEGYRRTS-APQDSENACED----------INECEEQEDLCSGGV 610
+G+ C PE S P+ A D +NEC+ LC+ G
Sbjct: 942 SIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT 1001
Query: 611 CINTDGSFLCDCDAGFEPSEDGTDCID 637
C NT GSF C C GF +C D
Sbjct: 1002 CRNTVGSFHCACAGGFALDAQERNCTD 1028
Score = 237 bits (580), Expect = 1e-61
Identities = 170/513 (33%), Positives = 219/513 (42%), Gaps = 93/513 (18%)
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGR 287
N +D+ CR +C NGRC T S+RCEC GYT G C DVDEC P G
Sbjct: 406 NQTIDI--CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDECTSSPCHHG- 461
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECP 345
C N G Y C C G++ R CVD DEC +C G C N G + C C
Sbjct: 462 ----DCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCN 517
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
AG+ CVD + C + + C +E ++ C+ P
Sbjct: 518 AGFELSPDGKNCVDHNE-----------CATST---MCVNGVCLNEDGSFSCLCK--PG- 560
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
F+ + GG + D+DEC+ P +CV G C NT+GSFRC+C G + DG
Sbjct: 561 ----FL-LAPGG----HYCMDIDECQT-PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRV 610
Query: 466 CVDA---DEC--ALDPRICGN---GT-------CSNTRGGY--ECQCSPGFTQGPDQTCV 508
CVD C A++ C GT C+N G+ CQ P Q
Sbjct: 611 CVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALC 670
Query: 509 -----------DVDECAEGRASCTFR-CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
D++ECA C C N GS+RC C GY A G C D+DEC
Sbjct: 671 SSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECAL 730
Query: 557 EPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTD 615
+C + C+N GSY C CP G+ QD+E C+D++EC C GVC N
Sbjct: 731 NSLLCDNGWCQNSPGSYSCSCPPGFHFW---QDTE-ICKDVDECLSSP--CVSGVCRNLA 784
Query: 616 GSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXX 675
GS+ C C G GT C+D GTC+ + RCE
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE--------------------VN 824
Query: 676 XXGHVTKAQCCCTLGAAWGSECELCPAPGSPAR 708
G +++CC TLGAAWGS CE C + AR
Sbjct: 825 LQGASLRSECCATLGAAWGSPCERCEIDPACAR 857
Score = 212 bits (517), Expect = 5e-54
Identities = 157/523 (30%), Positives = 203/523 (38%), Gaps = 74/523 (14%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAW---GAPC----------EACPPRGSPAH----TALCGE 52
CA + YLC C G+ GA C + C RG T C
Sbjct: 2177 CAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVC 2236
Query: 53 KPGEYINPVTNETKPID-ECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVD 111
PG P + E D EC P LC G C +T F+C CD G++ T C D+
Sbjct: 2237 PPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIR 2296
Query: 112 E----CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDC 167
+ + CR ++ EC C G P + C +++C HG
Sbjct: 2297 QGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGS- 2355
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN 227
GYT RDVDEC +C +G C N G++ CHC G+
Sbjct: 2356 -------------GYTAEG---RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDAT 2399
Query: 228 -NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C+D++EC + C C+NT GSF C C GY L DGR C+D+DEC H C
Sbjct: 2400 ATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNC- 2457
Query: 287 RDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVC-AGGECRNFNGGYVCECP 345
C NT G + C C G+ + C D DEC P C A G C N G + CEC
Sbjct: 2458 ---QFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECH 2514
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
G+ + C D + C RC QL C C +G +C
Sbjct: 2515 QGFTLVSSGHGCEDVNE--CDGPH---RCQHGCQNQLGGYRCSCPQGFTQHSQWAQCV-- 2567
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
D +EC + P C C NT G FRC CP G+
Sbjct: 2568 --------------------DENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGG 2607
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV 508
C D DECA C +C+NT GG+ C C G+ + CV
Sbjct: 2608 CQDVDECAGRRGPCSY-SCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 180 bits (438), Expect = 2e-44
Identities = 99/242 (40%), Positives = 122/242 (50%), Gaps = 22/242 (9%)
Query: 414 CQGGMGRPNLTQ----DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
CQ G P+ T D+DEC P C C NT GSF C CP GY+L DG +C D
Sbjct: 2390 CQAGY-TPDATATTCLDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDL 2447
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNT 527
DEC C C NT G + C+C PGFTQ Q C D DEC+ C CHNT
Sbjct: 2448 DECTSRQHNC-QFLCVNTVGAFTCRCPPGFTQH-HQACFDNDECSAQPGPCGAHGHCHNT 2505
Query: 528 AGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQ 587
GSFRC C G+ + + G C D++EC P C H C+N +G Y C CP+G+ + S Q
Sbjct: 2506 PGSFRCECHQGFTLVSSGHGCEDVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHS--Q 2562
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE------PSEDGTDCIDRRTG 641
++ C D NEC C C NT G F C C +GF+ +D +C RR G
Sbjct: 2563 WAQ--CVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRR-G 2619
Query: 642 TC 643
C
Sbjct: 2620 PC 2621
Score = 98.7 bits (235), Expect = 8e-20
Identities = 116/418 (27%), Positives = 158/418 (37%), Gaps = 56/418 (13%)
Query: 250 NTVGS-FRCECAPGYTLTADGRNCRDVDECDELPHPCGRD--GNPS-CTNTNGGYECSCG 305
N GS F C PG+ T GR+ V C CG P+ CT +G SCG
Sbjct: 58 NVCGSRFHAYCCPGWR-TFPGRSQCVVPICRRA---CGEGFCSQPNLCTCADGTLAPSCG 113
Query: 306 AG-WKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCE--CPAGWR-FDKTAAVCV--- 358
C++ C+ +C G G +C+ C G R CV
Sbjct: 114 VSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCACVYGF 173
Query: 359 -------DERKELCYDEWEAGRC-HRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
D R C+ + C H+ L + CC + G AWG CE CPA
Sbjct: 174 MGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHP-- 231
Query: 411 MRICQGGMGRPNL----TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
C+ G PN+ QD+DEC+ P +C GG CVN GSF C CP G+ L+ +C
Sbjct: 232 ---CRRGF-IPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAAC 287
Query: 467 VDADECALDPRICGNGTCSNTRGGY----ECQCSPG--FTQGPDQTCVDVDECAEGRASC 520
D A + G G C+ G+ +C C G + GP E + C
Sbjct: 288 EDYRAGACFSVLFG-GRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLC 346
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPE-G 579
R G P G G + + R+ PH GS P G
Sbjct: 347 AQRLPLLPGH-----P-GLFPGLLGFGSNGMGPPLGPARLNPH------GSDARGIPSLG 394
Query: 580 YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
++ + N DI C +LC G C+ T S+ C+C+ G+ G +CID
Sbjct: 395 PGNSNIGTATLNQTIDI--CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRG-ECID 449
Score = 98.3 bits (234), Expect = 1e-19
Identities = 46/113 (40%), Positives = 57/113 (50%), Gaps = 9/113 (7%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL--CHNT 798
D+DEC + C G F C C PG+ + C D DEC+ +P PC CHNT
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNT 2505
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
GS+ C C G+ L G C DV+EC+ H CQ C N G Y CSC G+
Sbjct: 2506 PGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHGCQNQLGGYRCSCPQGF 2557
Score = 97.9 bits (233), Expect = 1e-19
Identities = 51/124 (41%), Positives = 61/124 (49%), Gaps = 11/124 (8%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHN 797
D DECA LC APG +RC C G+ P + C DVDECA C N
Sbjct: 1362 DRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCEN 1421
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRG 855
G + C+C GYELD G NC D++EC + +C NT GSY CSC +E G
Sbjct: 1422 LPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481
Query: 856 DACV 859
CV
Sbjct: 1482 VGCV 1485
Score = 89.0 bits (211), Expect = 6e-17
Identities = 39/103 (37%), Positives = 54/103 (52%), Gaps = 4/103 (3%)
Query: 761 GRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDEDGA 817
G +RC C G+ + C D +ECA+ PP C C NT G + C+C +G++ D+
Sbjct: 2547 GGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALG 2606
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
C+DVDEC C C+NT G + C C GY + G CV
Sbjct: 2607 GCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 84.2 bits (199), Expect = 2e-15
Identities = 49/125 (39%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQ--LC 795
DVDEC P +C G F C C GY R C+DVDEC V CD C
Sbjct: 1238 DVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASC 1297
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEK 853
N GS+ C C G+ DG C D+DEC H C C N GSY C+C G+
Sbjct: 1298 LNIPGSFSCRCLPGWV--GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355
Query: 854 RGDAC 858
G C
Sbjct: 1356 DGFFC 1360
Score = 80.6 bits (190), Expect = 2e-14
Identities = 44/117 (37%), Positives = 53/117 (45%), Gaps = 12/117 (10%)
Query: 747 DVDECAAIPGLCA--------PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCH 796
D DEC+A PG C PG FRC C G+ +G C DV+EC P C C
Sbjct: 2485 DNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHGCQ 2543
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYE 852
N G Y C C G+ A C D +EC TC C NT G + C C G++
Sbjct: 2544 NQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFD 2600
Score = 73.3 bits (172), Expect = 3e-12
Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 7/95 (7%)
Query: 15 GVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIM 74
G+ TK LCC +VG AWG PCE CP + P + G N T + +DEC +
Sbjct: 202 GLVCTKALCCATVGRAWGLPCELCPAQPHPC-------RRGFIPNIHTGACQDVDECQAV 254
Query: 75 PQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
P LC+ G+C + F C C G+ ++S C D
Sbjct: 255 PGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 70.9 bits (166), Expect = 2e-11
Identities = 45/120 (37%), Positives = 58/120 (48%), Gaps = 12/120 (10%)
Query: 751 CAAIPGLCAPGRFRCVCG---PGYRP---AGEVCADVDECAVRPPPC-DQLCHNTDGSYD 803
C A P +P ++ +CG PG+ G+ D+DEC P C + +C N GS+
Sbjct: 1688 CEACPTPISPD-YQILCGNQAPGFLTDIHTGKPL-DIDECGEIPAICANGICINQIGSFR 1745
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE-KRGDACVG 860
C C G+ + C DVDEC CQQ C N GSY C C GY+ G ACVG
Sbjct: 1746 CECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVG 1805
Score = 50.4 bits (115), Expect = 3e-05
Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 32/149 (21%)
Query: 743 DVFADVDECAAIP---GLCA--PGRFRCVCGPGYR--PAGEVCADVDE--C--AVRPPPC 791
++ DVDEC + P G+C G + C CGPG R P+G C D + C ++ C
Sbjct: 762 EICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRC 821
Query: 792 DQLCHNTDGSYDCLCRTGY---------ELDE---------DGANCRDVDECERDTHTCQ 833
+ +C G E+D G C DV+ECE C
Sbjct: 822 EVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCP 881
Query: 834 Q-ICSNTEGSYECSCEDG--YEKRGDACV 859
C NT GS+ C C +G + G CV
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCV 910
Score = 48.0 bits (109), Expect = 1e-04
Identities = 57/195 (29%), Positives = 74/195 (37%), Gaps = 34/195 (17%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
GTC G C C GY T +C C G C +C+ G C C G
Sbjct: 128 GTCR----GASCLCQKGY----TGTVCGQ-PICDRG---CHNGGRCI---GPNRCACVYG 172
Query: 141 YRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRP 200
+ + P +CE D R G C +G C+ + L VC C+
Sbjct: 173 F-MGP---QCER-----DYRT---GPCFGQVGPEGCQ----HQLTGLVCTKALCCATVGR 216
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCEC 259
CE P A C GF + C DV+EC+ +C+ G C N VGSF C C
Sbjct: 217 AW-GLPCELCP-AQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRC 274
Query: 260 APGYTLTADGRNCRD 274
G+ L+ C D
Sbjct: 275 PVGHRLSDSSAACED 289
Score = 38.7 bits (86), Expect = 0.087
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGY 851
CR G+ + C+DVDEC+ CQ C N GS+ C C G+
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGH 278
>AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 728 bits (1799), Expect = 0.0
Identities = 355/869 (40%), Positives = 460/869 (52%), Gaps = 64/869 (7%)
Query: 9 SCAGAVGVPQTKYLCCCS--VGHAWGAPCEACPPRGSPAHTALCGEK-PGEYINPVTNET 65
+C + T+ +CCCS +G AW PCEACP SP + LCG + PG + T +
Sbjct: 1660 TCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKP 1719
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ 125
IDEC +P +C G C + F+C C G+ +++ C DVDEC PC+ A
Sbjct: 1720 LDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCECKPGY-- 182
C+N+PG++ C+C GY+L+P C +EC + +C HGDC +T GSY C C G+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPG-GACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQA 1838
Query: 183 TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE-GGM 241
+ + +C D+DEC R +P C NGTC+N+ G+Y C C GF N DCVD +EC G
Sbjct: 1839 SADQTLCMDIDECDR-QP-CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 242 VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
VCR G C NT GSF C C G+ LTADG+NC D +EC L C G +C N G +
Sbjct: 1897 VCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTC-LPG--TCQNLEGSFR 1953
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER 361
C C G+++ C+D DEC E P +C G C N G + C CP G+ C D R
Sbjct: 1954 CICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTR 2013
Query: 362 KELCYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMRICQGGMG 419
+ C+ +EAG+C + + CCCS+ G WG CE CP SA F +C G G
Sbjct: 2014 QSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHG 2073
Query: 420 R----PNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
+ +D++EC P VC G CVNTDGSFRCECP GY L G++CVD DEC++
Sbjct: 2074 AVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG 2133
Query: 476 PRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
CG GTC+N GG+EC C+ GF G TC D+DEC+ C FRCHNT GS+ CTC
Sbjct: 2134 -HPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTC 2192
Query: 536 PYGYAVAADGVHCRDIDECVQEPRVCPHA----CENVVGSYICKCPEGYRRTSAPQDSEN 591
P GY + DG CRD+DEC + C HA C+N++G++ C CP G R P E
Sbjct: 2193 PAGYTLREDGAMCRDVDECADGQQDC-HARGMECKNLIGTFACVCPPGMR--PLPGSGE- 2248
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGR 651
C D NEC Q DLC G C+NT GSF CDCD GF+PS T+C D R G C+ ++
Sbjct: 2249 GCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTM 2308
Query: 652 CEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDL 711
C VT+A+CCC G WG CELCP PG+ A L
Sbjct: 2309 CR------------------SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKL 2350
Query: 712 CTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCAPGRFRCVCGPGY 771
C + A + CA + + G FRC C GY
Sbjct: 2351 CP--------------HGSGYTAEGRDVDECRMLAHL--CAHGECINSLGSFRCHCQAGY 2394
Query: 772 RP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDT 829
P C D+DEC+ P PC LC NT GS+ C C GY L+EDG C+D+DEC
Sbjct: 2395 TPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQ 2454
Query: 830 HTCQQICSNTEGSYECSCEDGYEKRGDAC 858
H CQ +C NT G++ C C G+ + AC
Sbjct: 2455 HNCQFLCVNTVGAFTCRCPPGFTQHHQAC 2483
Score = 458 bits (1129), Expect = e-128
Identities = 268/748 (35%), Positives = 343/748 (45%), Gaps = 83/748 (11%)
Query: 151 EDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTLR-ENVCRDVDECSRPRPVCRNGTCE 208
+ +D C +C +G C T SYRCEC GYT C DVDEC+ C +G C
Sbjct: 407 QTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSP--CHHGDCV 464
Query: 209 NLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTA 267
N+PG Y C C GF+A P CVDV+EC G +C GRC NT GSF+C C G+ L+
Sbjct: 465 NIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSP 524
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELP 325
DG+NC D +EC C N C N +G + C C G+ L G C+D DEC + P
Sbjct: 525 DGKNCVDHNEC-ATSTMCV---NGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDEC-QTP 579
Query: 326 YVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER-KELCYDEWEAGRCHRARPLQLAR 384
+C G C N G + C+C G VCVD + CY E G C R P + +
Sbjct: 580 GICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTK 639
Query: 385 PECCCSE-GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCV 443
ECCC+ +G C+ CPA +SAEF +C G+G +D++EC + P+VC G C
Sbjct: 640 SECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCE 699
Query: 444 NTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
N GS+RC C GY G C D DECAL+ +C NG C N+ G Y C C PGF
Sbjct: 700 NLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQ 759
Query: 504 D-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP 562
D + C DVDEC + C N AGS+ C C G + G C D + ++
Sbjct: 760 DTEICKDVDECLSS-PCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQE 818
Query: 563 HACE-NVVGSYI---CKCPEGYRRTSAPQDSE--------------NACEDINECEEQED 604
CE N+ G+ + C G S + E C+D+NECE
Sbjct: 819 SRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPG 878
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXX 664
+C G C+NT GSF C+C G G C+D R C+ C
Sbjct: 879 VCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDEC------------ 926
Query: 665 XXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXX 724
G CCC++GA WG ECE CP P S LC
Sbjct: 927 --------GVTLPGKYLMDVCCCSIGAVWGVECEACPDPESLEFASLCP----------- 967
Query: 725 XXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLC-------APGRFRCVCGPGYRPAGEV 777
+ DV+EC PGLC G F C C G+ +
Sbjct: 968 ----RGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQE 1023
Query: 778 --CADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD-EDGANCRDVDECERDTHTCQ 833
C D+DEC + P C Q C NT GS++C C GYE NC DVDEC RD C+
Sbjct: 1024 RNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCR 1083
Query: 834 -QICSNTEGSYECSCEDGYE--KRGDAC 858
C+NT+GSY+C C G+E +G AC
Sbjct: 1084 GGTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Score = 442 bits (1090), Expect = e-123
Identities = 286/830 (34%), Positives = 359/830 (43%), Gaps = 101/830 (12%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+DEC P LC+ GTC +T ++C C G+E C D+DECS C QCV
Sbjct: 1072 VDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH-GQCV 1130
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
N+ GAF+C C G++ TP C D++EC Q C NT GSYRC C GY+L +
Sbjct: 1131 NVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPD 1190
Query: 188 --VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCR 244
C DVDEC VC G C N+PG + C C DGF A P+ CVDV+EC +C
Sbjct: 1191 GRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICL 1250
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
+G C NT GSF C C GY + C DVDEC+ H C D + SC N G + C C
Sbjct: 1251 HGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNC--DSHASCLNIPGSFSCRC 1308
Query: 305 GAGWKLVGRRCVDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
GW G C D DEC + C+ G+C N G Y C C G+ D DE E
Sbjct: 1309 LPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAE 1368
Query: 364 --------LCYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMR- 412
C + RC C + A G C + R
Sbjct: 1369 NVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRC 1428
Query: 413 ICQGGM----GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
IC GG G N T D++EC P C+ G C+NT GS+ C CP + L P G+ CVD
Sbjct: 1429 ICNGGYELDRGGGNCT-DINEC-ADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVD 1486
Query: 469 --ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRA---SCTFR 523
A C L+ G+ G C G C C+ GRA C
Sbjct: 1487 TRAGNCFLETHDRGDS-------GISCSAEIGVGVTRASCC-----CSLGRAWGNPCELC 1534
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHC--RDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
+R CP G + + DIDEC + P +C C N GS+ C+CP GY
Sbjct: 1535 PMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGY 1594
Query: 581 RRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRT 640
+ + CEDI+EC +C G C NT G++ C C A + G +C+D R
Sbjct: 1595 HLS----EHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRK 1650
Query: 641 GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCT--LGAAWGSECE 698
C+R +G C+ E +VT+ CCC+ +G AW CE
Sbjct: 1651 SVCFRH-YNGTCQNELAF--------------------NVTRKMCCCSYNIGQAWNRPCE 1689
Query: 699 LCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLC 758
CP P SP LC N P D+DEC IP +C
Sbjct: 1690 ACPTPISPDYQILCG--NQAPGFLTDIHTGKP---------------LDIDECGEIPAIC 1732
Query: 759 AP-------GRFRCVCGPG--YRPAGEVCADVDECAVRPPPCDQL--CHNTDGSYDCLCR 807
A G FRC C G Y C DVDEC R PC Q C N GSY C C
Sbjct: 1733 ANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCT 1792
Query: 808 TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
GY+L GA C +EC + C C +TEGSY C C G++ D
Sbjct: 1793 RGYKLSPGGA-CVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASAD 1841
Score = 430 bits (1060), Expect = e-120
Identities = 232/592 (39%), Positives = 291/592 (49%), Gaps = 47/592 (7%)
Query: 1 MEWNEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
+ W+E++ C + +CCCS+G WG CEACP S +LC G
Sbjct: 919 LRWDEDE--CGVTLPGKYLMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRD 976
Query: 61 VTNET---KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGR 117
+ K ++EC + P LC GTC +T F C C G+ D C D+DEC
Sbjct: 977 FLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISP 1036
Query: 118 PPCRGMAQCVNLPGAFECRCPPGYRLTPSL-DECEDVDECG-DQRICDHGDCRNTIGSYR 175
C G CVN PG+FEC C PGY L C DVDEC D +C G C NT GSY+
Sbjct: 1037 DLC-GQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYK 1095
Query: 176 CECKPGY--TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVD 232
C+C PG+ T + C D+DECS +C +G C N+ GA+ C C GF++ P+ CVD
Sbjct: 1096 CQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVD 1155
Query: 233 VNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
+NECR C + C NT GS+RC C GY+L DGR C DVDEC+E P C +
Sbjct: 1156 INECRVQNGGC-DVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQG---H 1211
Query: 293 CTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRF 350
CTN GG+ C C G+ R CVD DEC P++C G+C N G +VC C G+
Sbjct: 1212 CTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMV 1271
Query: 351 DKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
K A C D DE E G H C A+ C P S
Sbjct: 1272 RKGATGCSD------VDECEVGG-HN------------CDSHAS----CLNIPGSFSC-- 1306
Query: 411 MRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
R G +G DLDEC + C G C+N GS+RC C G+ A DG C D
Sbjct: 1307 -RCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCEDR 1363
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTA 528
DECA + +C NG C N GGY C+C GF D + C DVDECA+G C N
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLP 1423
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGY 580
G FRC C GY + G +C DI+EC C N GSY+C CP+ +
Sbjct: 1424 GMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDF 1475
Score = 407 bits (1001), Expect = e-112
Identities = 237/654 (36%), Positives = 309/654 (47%), Gaps = 78/654 (11%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C KPG + P + IDEC P +C G C +T F+C C G +C D
Sbjct: 555 CLCKPGFLLAPGGHYCMDIDECQT-PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVD 613
Query: 110 ----------VDECSWGRP--------------PCRGMAQ-CVNLPGA----FECRCPPG 140
+++ S RP P G + C P F+ C G
Sbjct: 614 THVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSG 673
Query: 141 YRLTPSLDECEDVDECG-DQRICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSR 197
+T + D++EC D +C +G C N GSYRC C GY + C DVDEC+
Sbjct: 674 LGITT---DGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECAL 730
Query: 198 PRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFR 256
+C NG C+N PG+Y C C GF + + C DV+EC C +G CRN GS+
Sbjct: 731 NSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYT 788
Query: 257 CECAPGYTLTADGRNCRD---------VDECDELPHPCGRDGNPSCTNTNG---GYEC-- 302
C+C PG L G C D + E + G C T G G C
Sbjct: 789 CKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCER 848
Query: 303 -----SCGAGW-KLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
+C G+ ++ G C D +EC+ P VC G C N G + CECP G D + +
Sbjct: 849 CEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRL 908
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
CVD R E C+ W+ C P + CCCS GA WG CE CP P+S EF +C
Sbjct: 909 CVDVRLEPCFLRWDEDECGVTLPGKYLMDVCCCSIGAVWGVECEACPDPESLEFASLCPR 968
Query: 417 GM---------GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
G+ GRP +D++EC+V P +C G C NT GSF C C G+ L +C
Sbjct: 969 GLGFASRDFLSGRP-FYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCT 1027
Query: 468 DADECALDPRICGNGTCSNTRGGYECQCSPGFTQG--PDQTCVDVDECAEGRASCT-FRC 524
D DEC + P +CG GTC NT G +EC+C PG+ G + C+DVDECA C C
Sbjct: 1028 DIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTC 1087
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRT 583
NT GS++C CP G+ + A G C DIDEC +CPH C NV+G++ C C G++ T
Sbjct: 1088 TNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQST 1147
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
Q C DINEC Q C CINT+GS+ C C G+ DG C D
Sbjct: 1148 PDRQ----GCVDINECRVQNGGCDVH-CINTEGSYRCSCGQGYSLMPDGRACAD 1196
Score = 405 bits (996), Expect = e-112
Identities = 224/611 (36%), Positives = 293/611 (47%), Gaps = 53/611 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDE--------------- 112
IDEC P LC GTC ++P FQC C G+ + H C D +
Sbjct: 1970 IDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVP 2029
Query: 113 ---------CSWGRPPCRGMAQ-CVNLP----GAFECRCPPGYRLTPSLDEC-EDVDECG 157
C + P G C P AF+ CP G+ P D+ EDV+EC
Sbjct: 2030 KAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECA 2089
Query: 158 DQR-ICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAY 214
+ +C +G C NT GS+RCEC GY+L C D DECS P C GTC N+ G +
Sbjct: 2090 ENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP-CGQGTCTNVIGGF 2148
Query: 215 LCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRD 274
C C DGF+ G C D++EC ++C RC NT GS+ C C GYTL DG CRD
Sbjct: 2149 ECACADGFEPGLMMTCEDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Query: 275 VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV---GRRCVDRDECKELPYVCAGG 331
VDEC + C G C N G + C C G + + G C D +EC P +C G
Sbjct: 2208 VDECADGQQDCHARGM-ECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNG 2266
Query: 332 ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLA--RPECCC 389
C N G + C+C G++ T C D R+ C+ E C A R ECCC
Sbjct: 2267 RCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCC 2326
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
G WG CE CP P ++ + ++C G G +D+DECR+ +C G C+N+ GSF
Sbjct: 2327 GGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSF 2386
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCV 508
RC C GY +C+D DEC+ P+ C C NT+G + C C G+ D +TC
Sbjct: 2387 RCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCK 2445
Query: 509 DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC-PHA-CE 566
D+DEC + +C F C NT G+F C CP G+ C D DEC +P C H C
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQA--CFDNDECSAQPGPCGAHGHCH 2503
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
N GS+ C+C +G+ S S + CED+NEC+ C G C N G + C C GF
Sbjct: 2504 NTPGSFRCECHQGFTLVS----SGHGCEDVNECDGPH-RCQHG-CQNQLGGYRCSCPQGF 2557
Query: 627 EPSEDGTDCID 637
C+D
Sbjct: 2558 TQHSQWAQCVD 2568
Score = 395 bits (972), Expect = e-109
Identities = 287/876 (32%), Positives = 377/876 (43%), Gaps = 134/876 (15%)
Query: 21 YLCCCSVGHAW---GAPCEACPPRGSPAH--TALCGEKPGEYIN--PVTNETKP--IDEC 71
+ C C+ G+ G C P + +C PG Y+ P E P +
Sbjct: 1426 FRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCV 1485
Query: 72 DIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG 131
D C T +G C + G S C + +WG P C + N
Sbjct: 1486 DTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCC-SLGR-AWGNP-CE-LCPMANTT- 1540
Query: 132 AFECRCPPGYRLTPSLDEC--EDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTLREN- 187
+ CP G P+ ED+DEC + +C GDC NT GS++CEC PGY L E+
Sbjct: 1541 EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHT 1600
Query: 188 -VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF-KAGPNNDCVDVNECREGGMVC-- 243
+C D+DECS +C GTC N G Y C C + + N+C+D+ + VC
Sbjct: 1601 RICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKS-----VCFR 1655
Query: 244 -RNGRCRNTVGS--FRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGY 300
NG C+N + R C Y + C+ P P D C N G+
Sbjct: 1656 HYNGTCQNELAFNVTRKMCCCSYNIGQAWNR-----PCEACPTPISPDYQILCGNQAPGF 1710
Query: 301 ECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
G L D DEC E+P +CA G C N G + CECPAG+ ++ C D
Sbjct: 1711 LTDIHTGKPL------DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACED- 1763
Query: 361 RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG--M 418
DE + R P Q +C G+ RC ++ GG +
Sbjct: 1764 -----VDECGS----RESPCQ-QNADCINIPGSY------RCKCTRG---YKLSPGGACV 1804
Query: 419 GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRI 478
GR +ECR P+VC G C++T+GS+ C C G+ + D C+D DEC P
Sbjct: 1805 GR-------NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQP-- 1855
Query: 479 CGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAE--GRASCTF-RCHNTAGSFRCTC 535
CGNGTC N G Y C C PGF + CVD DEC G+ C F C NTAGSF C C
Sbjct: 1856 CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQV-CRFGHCLNTAGSFHCLC 1914
Query: 536 PYGYAVAADGVHCRDIDECVQEPRVC-PHACENVVGSYICKCPEGYRRTSAPQDSENACE 594
G+ + ADG +C D +EC+ C P C+N+ GS+ C CP G+ Q + C
Sbjct: 1915 QDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGF------QVQSDHCI 1968
Query: 595 DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEP 654
DI+EC E+ +LC G C N+ GSF C C GF S++G C D R C+ +G+C
Sbjct: 1969 DIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSV 2028
Query: 655 EXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTL--GAAWGSECELCPAPGSPARLDLC 712
+ TK +CCC+ G WG CELCP GS A +LC
Sbjct: 2029 PKAF--------------------NTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELC 2068
Query: 713 TAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCA-------PGRFRC 765
P D DV+ECA PG+C G FRC
Sbjct: 2069 ------PFGHGAVPGPD-------------DSREDVNECAENPGVCTNGVCVNTDGSFRC 2109
Query: 766 VCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
C GY G C D DEC+V P C N G ++C C G+E C D+D
Sbjct: 2110 ECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLM-MTCEDID 2168
Query: 824 ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 859
EC + C C NTEGSY C+C GY R D +
Sbjct: 2169 ECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAM 2204
Score = 380 bits (935), Expect = e-104
Identities = 219/596 (36%), Positives = 284/596 (47%), Gaps = 43/596 (7%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
CG+ G + P +DEC+ P++C G C + P G +C C G+ C D
Sbjct: 1181 CGQ--GYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVD 1238
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC--GDQRICDHGDC 167
VDEC C C N G+F C C GY + C DVDEC G H C
Sbjct: 1239 VDECDLNPHICLH-GDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASC 1297
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGP 226
N GS+ C C PG+ C D+DEC C G C N+PG+Y C C GF AG
Sbjct: 1298 LNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF-AGD 1356
Query: 227 NNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C D +EC E +C NG+C N G +RCEC G+ T D R C+DVDEC + + C
Sbjct: 1357 GFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ-GNLCA 1415
Query: 287 RDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
SC N G + C C G++L G C D +EC + P C G C N G Y+C C
Sbjct: 1416 FG---SCENLPGMFRCICNGGYELDRGGGNCTDINECAD-PVNCINGVCINTPGSYLCSC 1471
Query: 345 PAGWRFDKTAAVCVDERKELCY----DEWEAG-RCHRARPLQLARPECCCSEGAAWGRYC 399
P + + + CVD R C+ D ++G C + + R CCCS G AWG C
Sbjct: 1472 PQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPC 1531
Query: 400 ERCPAPDSAEFMRICQGGMG-RPN----LTQDLDECRVRPDVCVGGRCVNTDGSFRCECP 454
E CP ++ E+ +C GG G +PN + +D+DEC+ P +C GG CVNT GSF+CECP
Sbjct: 1532 ELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECP 1591
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ-GPDQTCVDVDEC 513
GY L+ C D DEC+ ICG GTC NT G Y C C + Q C+D+
Sbjct: 1592 PGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDM--- 1648
Query: 514 AEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVG-S 571
R S FR +N C + V C +I + P C AC +
Sbjct: 1649 ---RKSVCFRHYNGT----CQNELAFNVTRKMCCCSYNIGQAWNRP--C-EACPTPISPD 1698
Query: 572 YICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
Y C G + D DI+EC E +C+ G+CIN GSF C+C AGF
Sbjct: 1699 YQILC--GNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGF 1752
Score = 372 bits (914), Expect = e-102
Identities = 242/661 (36%), Positives = 302/661 (45%), Gaps = 88/661 (13%)
Query: 11 AGAVGVPQ----TKYLCCCSV--GHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNE 64
AG VP+ TK CCCS G WG PCE CP GS A LC G P +
Sbjct: 2023 AGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGP-DDS 2081
Query: 65 TKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+ ++EC P +C G C +T F+C C GY D T C D DECS G P C G
Sbjct: 2082 REDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP-C-GQG 2139
Query: 125 QCVNLPGAFECRCPPGYRLTPSLD-ECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYT 183
C N+ G FEC C G+ P L CED+DEC + C NT GSY C C GYT
Sbjct: 2140 TCTNVIGGFECACADGFE--PGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYT 2197
Query: 184 LREN--VCRDVDECSRPRPVC--RNGTCENLPGAYLCHCDDGFKA--GPNNDCVDVNECR 237
LRE+ +CRDVDEC+ + C R C+NL G + C C G + G C D NEC
Sbjct: 2198 LREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECH 2257
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE-----------CDELPHP-- 284
+C NGRC NT GSFRC+C G+ + C D+ + C L
Sbjct: 2258 AQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSE 2317
Query: 285 --------CG--RDGNPSCTNT----NGGYE--CSCGAGWKLVGRRCVDRDECKELPYVC 328
CG R P C Y C G+G+ GR D DEC+ L ++C
Sbjct: 2318 AVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGR---DVDECRMLAHLC 2374
Query: 329 AGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECC 388
A GEC N G + C C AG+ D TA C+D DE C Q+ +P C
Sbjct: 2375 AHGECINSLGSFRCHCQAGYTPDATATTCLD------MDE-----CS-----QVPKP-CT 2417
Query: 389 CSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGS 448
G + CP E + G +DLDEC R C CVNT G+
Sbjct: 2418 FLCKNTKGSFLCSCPRGYLLE-----EDG----RTCKDLDECTSRQHNCQF-LCVNTVGA 2467
Query: 449 FRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQ-GPDQT 506
F C CP G+ +C D DEC+ P CG +G C NT G + C+C GFT
Sbjct: 2468 FTCRCPPGFTQHHQ--ACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHG 2525
Query: 507 CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-C 565
C DV+EC +G C C N G +RC+CP G+ + C D +EC P C A C
Sbjct: 2526 CEDVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASC 2584
Query: 566 ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
N +G + C CP G+ A C+D++EC + CS C NT G FLC C G
Sbjct: 2585 RNTLGGFRCVCPSGFDFDQAL----GGCQDVDECAGRRGPCSYS-CANTPGGFLCGCPQG 2639
Query: 626 F 626
+
Sbjct: 2640 Y 2640
Score = 363 bits (894), Expect = 1e-99
Identities = 248/698 (35%), Positives = 303/698 (43%), Gaps = 87/698 (12%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPID 69
C VG Q C V +PC P T C PG P +D
Sbjct: 433 CECNVGYTQDVRGECIDVDECTSSPCHHGDCVNIPG-TYHCRCYPGFQATPTRQACVDVD 491
Query: 70 ECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
EC + LC G C +T FQC C+ G+E C D +EC+ G+ C+N
Sbjct: 492 ECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGV--CLNE 549
Query: 130 PGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN-- 187
G+F C C PG+ L P C D+DEC IC +G C NT GS+RC+C G + +
Sbjct: 550 DGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGR 609
Query: 188 VCRDVD------------ECSRPRP--VCRNGTCENLPG------AYLCHCDDG--FKA- 224
VC D C+RP P V ++ C P LC + F+A
Sbjct: 610 VCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQAL 669
Query: 225 -----GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECD 279
G D D+NEC VC NG C N GS+RC C GY A G++C DVDEC
Sbjct: 670 CSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECA 729
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFN 337
C N C N+ G Y CSC G+ C D DEC P C G CRN
Sbjct: 730 LNSLLCD---NGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLA 784
Query: 338 GGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGR 397
G Y C+C G R D + C+D K C+ + + RC R ECC + GAAWG
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGS 844
Query: 398 YCERCPAPDSAEFMRICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPD 455
CERC E C G R D++EC P VC GRCVNT GSFRCECP+
Sbjct: 845 PCERC------EIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPE 898
Query: 456 GYVLAPDGLSCVDA--DECAL--DPRICG--------NGTCSNTRG---GYECQCSP--- 497
G +L G CVD + C L D CG C + G G EC+ P
Sbjct: 899 GLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYLMDVCCCSIGAVWGVECEACPDPE 958
Query: 498 ------------GFTQ----GPDQTCVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYA 540
GF DV+EC CT C NT GSF C C G+A
Sbjct: 959 SLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFA 1018
Query: 541 VAADGVHCRDIDECVQEPRVCPH-ACENVVGSYICKCPEGYRRTSAPQDSENACEDINEC 599
+ A +C DIDEC P +C C N GS+ C+C GY S +N C D++EC
Sbjct: 1019 LDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYE--SGFMLMKN-CMDVDEC 1075
Query: 600 EEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
LC GG C NTDGS+ C C G E + GT C D
Sbjct: 1076 ARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACED 1113
Score = 356 bits (876), Expect = 2e-97
Identities = 213/603 (35%), Positives = 278/603 (46%), Gaps = 41/603 (6%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC LC G C + P G++C C+ G++ C+DVDEC+ G G C N
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFG--SCEN 1421
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENV 188
LPG F C C GY L C D++EC D C +G C NT GSY C C + L +
Sbjct: 1422 LPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481
Query: 189 CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC 248
VD + C T + C + G + C + R G C
Sbjct: 1482 VGCVDTRAGN---CFLETHDRGDSGISCSAEIGVGVTRASCCCSLG--RAWGNPCELCPM 1536
Query: 249 RNTVGSFRCECAPGYTLTADGRNC--RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
NT +R C G + D+DEC ELP C + G+ C NT G ++C C
Sbjct: 1537 ANTT-EYRTLCPGGEGFQPNRITVILEDIDECQELPGLC-QGGD--CVNTFGSFQCECPP 1592
Query: 307 GWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKEL 364
G+ L R C D DEC +C G C N G Y C CPA + C+D RK +
Sbjct: 1593 GYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSV 1652
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMRICQGGMGRPN 422
C+ + G C + R CCCS G AW R CE CP P S ++ +C G
Sbjct: 1653 CFRHYN-GTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILC-GNQAPGF 1710
Query: 423 LTQ-------DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
LT D+DEC P +C G C+N GSFRCECP G+ L+C D DEC
Sbjct: 1711 LTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSR 1770
Query: 476 PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRC 533
C N C N G Y C+C+ G+ P CV +EC E C+ C +T GS+ C
Sbjct: 1771 ESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMC 1830
Query: 534 TCPYGYAVAADGVHCRDIDECVQEPRVCPH-ACENVVGSYICKCPEGYRRTSAPQDSENA 592
C G+ +AD C DIDEC ++P C + C+N++GSY C C G+ T
Sbjct: 1831 LCHRGFQASADQTLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGFVVT-----HNGD 1883
Query: 593 CEDINECEE-QEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGR 651
C D +EC +C G C+NT GSF C C GFE + DG +C+D T C ++G
Sbjct: 1884 CVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVD--TNECLS--LAGT 1939
Query: 652 CEP 654
C P
Sbjct: 1940 CLP 1942
Score = 343 bits (842), Expect = 2e-93
Identities = 209/655 (31%), Positives = 294/655 (44%), Gaps = 59/655 (9%)
Query: 9 SCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPI 68
SC+ +GV T+ CCCS+G AWG PCE CP + + LC G N +T + I
Sbjct: 1505 SCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDI 1564
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC +P LC+ G C +T FQC C GY + +C D+DECS C G C N
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGTCYN 1623
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTI--GSYRCECKPGYTLRE 186
G + C CP Y + C D+ + R +G C+N + R C Y + +
Sbjct: 1624 TLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHY-NGTCQNELAFNVTRKMCCCSYNIGQ 1682
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
R + C P C N +L G +D++EC E +C NG
Sbjct: 1683 AWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTG-------KPLDIDECGEIPAICANG 1735
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
C N +GSFRCEC G+ + C DVDEC PC + N C N G Y C C
Sbjct: 1736 ICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQ--NADCINIPGSYRCKCTR 1793
Query: 307 GWKL-VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
G+KL G CV R+EC+E+P VC+ G+C + G Y+C C G++ +C+D
Sbjct: 1794 GYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMD------ 1847
Query: 366 YDEWEAGRCHRARPLQ-LARPECCCSEG----------------AAWGRYCERCPAPDSA 408
DE + C + C C G G+ C ++A
Sbjct: 1848 IDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTA 1907
Query: 409 -EFMRICQGGM---GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
F +CQ G D +EC C+ G C N +GSFRC CP G+ + D
Sbjct: 1908 GSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSD-- 1965
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
C+D DEC+ +P +C GTC+N+ G ++C C PGF + C + R S C
Sbjct: 1966 HCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG-----HRCFDTRQSF---C 2017
Query: 525 HNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEP-RVCPHACENVVGSYICKCPEGYRR 582
+ +C+ P + C + E +P +CP + ++ CP G+
Sbjct: 2018 FTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCP---QEGSAAFQELCPFGHGA 2074
Query: 583 TSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
P DS ED+NEC E +C+ GVC+NTDGSF C+C G+ G +C+D
Sbjct: 2075 VPGPDDSR---EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVD 2126
Score = 336 bits (826), Expect = 2e-91
Identities = 216/646 (33%), Positives = 295/646 (45%), Gaps = 65/646 (10%)
Query: 23 CCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGT 82
CC ++G AWG+PCE C PA G VT + ++EC+ P +C G
Sbjct: 834 CCATLGAAWGSPCERCEI--DPACARGFARMTG-----VTCDD--VNECESFPGVCPNGR 884
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDV--DEC--SWGRPPCRGMAQCVNLPGAF---EC 135
C +T F+C C G D + LC DV + C W C V LPG + C
Sbjct: 885 CVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECG-----VTLPGKYLMDVC 939
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDEC 195
C G + C D + +C G +G + G +DV+EC
Sbjct: 940 CCSIGAVWGVECEACPDPESLEFASLCPRG-----LGFASRDFLSGRPFY----KDVNEC 990
Query: 196 SRPRPVCRNGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRNGRCRNTVGS 254
+C +GTC N G++ C C GF +C D++ECR +C G C NT GS
Sbjct: 991 KVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGS 1050
Query: 255 FRCECAPGYTLTAD-GRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV-- 311
F CEC PGY +NC DVDEC P C R G +CTNT+G Y+C C G +L
Sbjct: 1051 FECECFPGYESGFMLMKNCMDVDECARDPLLC-RGG--TCTNTDGSYKCQCPPGHELTAK 1107
Query: 312 GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK--------- 362
G C D DEC +C G+C N G + C C AG++ CVD +
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCD 1167
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCS---EGAAWGRYCERCPAPDSAEFMR-ICQGG- 417
C + + RC + L C+ E R C++ + R +C G
Sbjct: 1168 VHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGF 1227
Query: 418 MGRPNLTQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
M P++ D+DEC + P +C+ G C NT GSF C C GY++ C D DEC +
Sbjct: 1228 MATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVG 1287
Query: 476 PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFR 532
C + +C N G + C+C PG+ G C D+DEC C+ R C N GS+R
Sbjct: 1288 GHNCDSHASCLNIPGSFSCRCLPGWV-GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYR 1346
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSEN 591
CTC G+A DG C D DEC + +C + C N G Y C+C G+ P +
Sbjct: 1347 CTCRQGFA--GDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFD----PTEDHR 1400
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
AC+D++EC Q +LC+ G C N G F C C+ G+E G +C D
Sbjct: 1401 ACQDVDEC-AQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTD 1445
Score = 329 bits (808), Expect = 3e-89
Identities = 239/714 (33%), Positives = 308/714 (43%), Gaps = 111/714 (15%)
Query: 21 YLCCCSVGHAWGAPCEACPPRGSPAHTAL------CGEKPGEYINPV---------TNET 65
Y C C++G+ GA + C A +L C PG Y T
Sbjct: 705 YRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEIC 764
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS-WGR---PPCR 121
K +DEC P C G C + + C C G D + C D + + W + C
Sbjct: 765 KDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE 822
Query: 122 GMAQ--------CVNLPGAF-----ECR----CPPGYRLTPSLDECEDVDECGD-QRICD 163
Q C L A+ C C G+ + C+DV+EC +C
Sbjct: 823 VNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVT-CDDVNECESFPGVCP 881
Query: 164 HGDCRNTIGSYRCECKPGYTLREN--VCRDV-----------DECSRPRP--------VC 202
+G C NT GS+RCEC G L + +C DV DEC P C
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYLMDVCCC 941
Query: 203 RNGT-----CENLPG------AYLCHCDDGFKA----GPNNDCVDVNECREGGMVCRNGR 247
G CE P A LC GF + DVNEC+ +C +G
Sbjct: 942 SIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT 1001
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
CRNTVGSF C CA G+ L A RNC D+DEC P CG+ +C NT G +EC C G
Sbjct: 1002 CRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG---TCVNTPGSFECECFPG 1058
Query: 308 WK---LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKE 363
++ ++ + C+D DEC P +C GG C N +G Y C+CP G C D +
Sbjct: 1059 YESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECS 1118
Query: 364 L---------CYDEWEAGRC--HRARPLQLARPECC-CSEGAAWGRYCE-RCPAPDSAEF 410
L C + A +C H R C +E C+ C + +
Sbjct: 1119 LSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYR 1178
Query: 411 MRICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
QG P+ D+DEC P VC G C N G RC C DG++ PD +CVD
Sbjct: 1179 CSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVD 1238
Query: 469 ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFR--CH 525
DEC L+P IC +G C NT+G + C C G+ T C DVDEC G +C C
Sbjct: 1239 VDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCL 1298
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECV-QEPRVCPHA-CENVVGSYICKCPEGYRRT 583
N GSF C C G+ DG C D+DECV QE R P C NV GSY C C +G+
Sbjct: 1299 NIPGSFSCRCLPGWV--GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGD 1356
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
CED +EC E DLC G C+N G + C+C+ GF+P+ED C D
Sbjct: 1357 GF------FCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 290 bits (711), Expect = 2e-77
Identities = 192/556 (34%), Positives = 250/556 (44%), Gaps = 83/556 (14%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC + C GTC + GF+C C G+E C D+DECS C +C N
Sbjct: 2128 DECSV-GHPCGQGTCTNVIGGFECACADGFE-PGLMMTCEDIDECSLNPLLCA--FRCHN 2183
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICD-HG-DCRNTIGSYRCECKPGYTLR 185
G++ C CP GY L C DVDEC D Q+ C G +C+N IG++ C C PG
Sbjct: 2184 TEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPL 2243
Query: 186 ENV---CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF------------KAGP---- 226
C D +EC +C NG C N G++ C CD+GF + GP
Sbjct: 2244 PGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAE 2303
Query: 227 -----------NNDCVDVNECREGGMVCRNGRCRNT----VGSFRCECAPGYTLTADGRN 271
+++ V EC GG RC ++R C G TA+GR
Sbjct: 2304 VLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGR- 2362
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK--LVGRRCVDRDECKELPYVCA 329
DVDEC L H C C N+ G + C C AG+ C+D DEC ++P C
Sbjct: 2363 --DVDECRMLAHLCAHG---ECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCT 2417
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C+N G ++C CP G+ ++ C D DE + R H + L C
Sbjct: 2418 F-LCKNTKGSFLCSCPRGYLLEEDGRTCKD------LDECTS-RQHNCQFL------CVN 2463
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGS 448
+ GA + RCP P + + C D DEC +P C G C NT GS
Sbjct: 2464 TVGA----FTCRCP-PGFTQHHQACF----------DNDECSAQPGPCGAHGHCHNTPGS 2508
Query: 449 FRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-C 507
FRCEC G+ L G C D +EC P C +G C N GGY C C GFTQ C
Sbjct: 2509 FRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQC 2566
Query: 508 VDVDECAEGRASC-TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
VD +ECA +C + C NT G FRC CP G+ C+D+DEC C ++C
Sbjct: 2567 VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYSCA 2626
Query: 567 NVVGSYICKCPEGYRR 582
N G ++C CP+GY R
Sbjct: 2627 NTPGGFLCGCPQGYFR 2642
Score = 290 bits (711), Expect = 2e-77
Identities = 195/525 (37%), Positives = 244/525 (46%), Gaps = 87/525 (16%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC--RGMAQ 125
IDEC + P LC CH+T + C C GY +CRDVDEC+ G+ C RGM +
Sbjct: 2167 IDECSLNPLLCA-FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGM-E 2224
Query: 126 CVNLPGAFECRCPPGYRLTPSLDE-CEDVDECGDQR-ICDHGDCRNTIGSYRCECKPGY- 182
C NL G F C CPPG R P E C D +EC Q +C +G C NT GS+RC+C G+
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 183 ---TLRE---------------NVCRDVDECS----RPRPVCRNGT-----CE--NLPG- 212
TL E +CR + S R C G CE LPG
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGT 2344
Query: 213 -AYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRN 271
AY C G +G + DV+ECR +C +G C N++GSFRC C GYT A
Sbjct: 2345 SAYRKLCPHG--SGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATT 2402
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCA 329
C D+DEC ++P PC C NT G + CSC G+ L GR C D DEC + C
Sbjct: 2403 CLDMDECSQVPKPC----TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQ 2458
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C N G + C CP G+ + + C+D E A+P C
Sbjct: 2459 F-LCVNTVGAFTCRCPPGFT----------QHHQACFDNDECS----------AQPGPCG 2497
Query: 390 SEGAAWGRYCERCPAPDSAEFMR---ICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTD 446
+ G +C P E + + G G +D++EC P C G C N
Sbjct: 2498 AHG-----HCHNTPGSFRCECHQGFTLVSSGHG----CEDVNECD-GPHRCQHG-CQNQL 2546
Query: 447 GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT 506
G +RC CP G+ CVD +ECAL P CG+ +C NT GG+ C C GF DQ
Sbjct: 2547 GGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDF--DQA 2604
Query: 507 ---CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC 548
C DVDECA R C++ C NT G F C CP GY A G HC
Sbjct: 2605 LGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG-HC 2648
Score = 287 bits (704), Expect = 1e-76
Identities = 241/778 (30%), Positives = 309/778 (39%), Gaps = 109/778 (14%)
Query: 122 GMAQCVNLPGAFECR--CPPGYRLTPSLDECED---VDECGDQRICDHG-DCRN--TIGS 173
G +QCV +P CR C G+ P+L C D CG R C N T
Sbjct: 77 GRSQCV-VP---ICRRACGEGFCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMNGGTCRG 132
Query: 174 YRCECKPGYTLRENVCRDVDECSRPRPVCRNG-------TCENLPGAYLCHCDDGFKAGP 226
C C+ GYT VC C R C NG C + G C+ ++ GP
Sbjct: 133 ASCLCQKGYT--GTVCGQ-PICDRG---CHNGGRCIGPNRCACVYGFMGPQCERDYRTGP 186
Query: 227 NNDCVDVNECREG--GMVCRNGRCRNTVG---SFRCECAP--------GYTLTADGRNCR 273
V C+ G+VC C TVG CE P G+ C+
Sbjct: 187 CFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQ 246
Query: 274 DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPY-VCAGGE 332
DVDEC +P C G SC N G + C C G +L D + V GG
Sbjct: 247 DVDECQAVPGLC--QGG-SCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGR 303
Query: 333 CRNFNGGYV----CECPAG--WRFDKTAAVCV----DERKELCYDEWEAGRCHRAR-PLQ 381
C G+ C C G W +C +E ++LC H P
Sbjct: 304 CAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGL 363
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
L R + +G L Q +D CR ++C+ GR
Sbjct: 364 LGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGR 423
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
C+ T S+RCEC GY G C+D DEC P C +G C N G Y C+C PGF
Sbjct: 424 CLPTPSSYRCECNVGYTQDVRG-ECIDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQA 480
Query: 502 GPD-QTCVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPR 559
P Q CVDVDEC C RC NT GSF+C C G+ ++ DG +C D +EC
Sbjct: 481 TPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 560 VCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFL 619
C N GS+ C C G+ AP + C DI+EC + +C G C NT+GSF
Sbjct: 541 CVNGVCLNEDGSFSCLCKPGF--LLAP--GGHYCMDIDEC-QTPGICVNGHCTNTEGSFR 595
Query: 620 CDCDAGFEPSEDGTDCIDRRT-GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXG 678
C C G DG C+D TCY ++ G C G
Sbjct: 596 CQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSC--------------------ARPFPG 635
Query: 679 HVTKAQCCC-TLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXX 737
VTK++CCC +G C+LCPA S LC++
Sbjct: 636 TVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSS----------------GLGITTD 679
Query: 738 XXXXLDVFADVDECAAIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ 793
+ D + CA G+C G +RCVC GY +G+ C DVDECA+ CD
Sbjct: 680 GRDINECALDPEVCA--NGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDN 737
Query: 794 -LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
C N+ GSY C C G+ +D C+DVDEC + +C N GSY C C G
Sbjct: 738 GWCQNSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPG 794
Score = 263 bits (644), Expect = 2e-69
Identities = 204/618 (33%), Positives = 258/618 (41%), Gaps = 70/618 (11%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGA-PC-EACPPRGSPAHTALCGEK-------PGEYINP 60
CAG + T+ CCC G W A P E CPPRGS LC ++ PG +
Sbjct: 304 CAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGL 363
Query: 61 VTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+ + + + P P H + G + T+ L + +D C C
Sbjct: 364 LGFGSNGMGP-PLGPARLNP---HGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLC 419
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
+C+ P ++ C C GY EC DVDEC C HGDC N G+Y C C P
Sbjct: 420 LN-GRCLPTPSSYRCECNVGY-TQDVRGECIDVDECTSSP-CHHGDCVNIPGTYHCRCYP 476
Query: 181 GY--TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECR 237
G+ T C DVDEC +C G C N G++ C C+ GF+ P+ +CVD NEC
Sbjct: 477 GFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECA 536
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTN 297
M C NG C N GSF C C PG+ L G C D+DEC + P C N CTNT
Sbjct: 537 TSTM-CVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDEC-QTPGIC---VNGHCTNTE 591
Query: 298 GGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGEC-RNFNGGYV---CECP-AGWRF 350
G + C C G + GR CVD G C R F G C C F
Sbjct: 592 GSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGF 651
Query: 351 DKTAAVC----VDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPD 406
+ +C E + LC R PE C + R RC
Sbjct: 652 GEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNL 711
Query: 407 SAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
E G G+ D+DEC + +C G C N+ GS+ C CP G+ D C
Sbjct: 712 GYE-----AGASGKD--CTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEIC 764
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDE--C----AEGR-- 517
D DEC P C +G C N G Y C+C PG P T C+D + C E R
Sbjct: 765 KDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE 822
Query: 518 -----ASCTFRCHNTAGSF------RC----TCPYGYAVAADGVHCRDIDECVQEPRVCP 562
AS C T G+ RC C G+A GV C D++EC P VCP
Sbjct: 823 VNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFA-RMTGVTCDDVNECESFPGVCP 881
Query: 563 HA-CENVVGSYICKCPEG 579
+ C N GS+ C+CPEG
Sbjct: 882 NGRCVNTAGSFRCECPEG 899
Score = 258 bits (633), Expect = 5e-68
Identities = 221/687 (32%), Positives = 281/687 (40%), Gaps = 129/687 (18%)
Query: 40 PRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYE 99
P GS A + PG + ID C LC G C TP+ ++C C+ GY
Sbjct: 382 PHGSDAR-GIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYT 440
Query: 100 HDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GD 158
D C DVDEC+ PC CVN+PG + CRC PG++ TP+ C DVDEC
Sbjct: 441 QDVRGE-CIDVDECT--SSPCH-HGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVS 496
Query: 159 QRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLC 216
+C G C NT GS++C C G+ L + C D +EC+ +C NG C N G++ C
Sbjct: 497 GGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECA-TSTMCVNGVCLNEDGSFSC 555
Query: 217 HCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV 275
C GF P C+D++EC+ G +C NG C NT GSFRC+C G + DGR C D
Sbjct: 556 LCKPGFLLAPGGHYCMDIDECQTPG-ICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDT 614
Query: 276 ---DEC--------DELPHP---------CGRD----GNPS--CTNTNGG-YECSCGAGW 308
C P P C G P C N ++ C +G
Sbjct: 615 HVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGL 674
Query: 309 KLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCY 366
+ GR D +EC P VCA G C N G Y C C G+ + C D
Sbjct: 675 GITTDGR---DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTD------V 725
Query: 367 DEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM---GRPNL 423
DE C A C G +C+ P S C G +
Sbjct: 726 DE-----C--------ALNSLLCDNG-----WCQNSPGSYSCS----CPPGFHFWQDTEI 763
Query: 424 TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA---------DECAL 474
+D+DEC P CV G C N GS+ C+C G L P G C+D+ E
Sbjct: 764 CKDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRC 821
Query: 475 DPRICG---NGTCSNTRG---GYECQ-------CSPGFTQGPDQTCVDVDECAEGRASC- 520
+ + G C T G G C+ C+ GF + TC DV+EC C
Sbjct: 822 EVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCP 881
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRDI-----------DEC-VQEP-----RVCPH 563
RC NTAGSFRC CP G + A G C D+ DEC V P VC
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYLMDVCCC 941
Query: 564 ACENVVG------------SYICKCPEGYRRTSAP-QDSENACEDINECEEQEDLCSGGV 610
+ V G + CP G S +D+NEC+ LC+ G
Sbjct: 942 SIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT 1001
Query: 611 CINTDGSFLCDCDAGFEPSEDGTDCID 637
C NT GSF C C GF +C D
Sbjct: 1002 CRNTVGSFHCACAGGFALDAQERNCTD 1028
Score = 237 bits (580), Expect = 1e-61
Identities = 170/513 (33%), Positives = 219/513 (42%), Gaps = 93/513 (18%)
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGR 287
N +D+ CR +C NGRC T S+RCEC GYT G C DVDEC P G
Sbjct: 406 NQTIDI--CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDECTSSPCHHG- 461
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECP 345
C N G Y C C G++ R CVD DEC +C G C N G + C C
Sbjct: 462 ----DCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCN 517
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
AG+ CVD + C + + C +E ++ C+ P
Sbjct: 518 AGFELSPDGKNCVDHNE-----------CATST---MCVNGVCLNEDGSFSCLCK--PG- 560
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
F+ + GG + D+DEC+ P +CV G C NT+GSFRC+C G + DG
Sbjct: 561 ----FL-LAPGG----HYCMDIDECQT-PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRV 610
Query: 466 CVDA---DEC--ALDPRICGN---GT-------CSNTRGGY--ECQCSPGFTQGPDQTCV 508
CVD C A++ C GT C+N G+ CQ P Q
Sbjct: 611 CVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALC 670
Query: 509 -----------DVDECAEGRASCTFR-CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
D++ECA C C N GS+RC C GY A G C D+DEC
Sbjct: 671 SSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECAL 730
Query: 557 EPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTD 615
+C + C+N GSY C CP G+ QD+E C+D++EC C GVC N
Sbjct: 731 NSLLCDNGWCQNSPGSYSCSCPPGFHFW---QDTE-ICKDVDECLSSP--CVSGVCRNLA 784
Query: 616 GSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXX 675
GS+ C C G GT C+D GTC+ + RCE
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE--------------------VN 824
Query: 676 XXGHVTKAQCCCTLGAAWGSECELCPAPGSPAR 708
G +++CC TLGAAWGS CE C + AR
Sbjct: 825 LQGASLRSECCATLGAAWGSPCERCEIDPACAR 857
Score = 212 bits (517), Expect = 5e-54
Identities = 157/523 (30%), Positives = 203/523 (38%), Gaps = 74/523 (14%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAW---GAPC----------EACPPRGSPAH----TALCGE 52
CA + YLC C G+ GA C + C RG T C
Sbjct: 2177 CAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVC 2236
Query: 53 KPGEYINPVTNETKPID-ECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVD 111
PG P + E D EC P LC G C +T F+C CD G++ T C D+
Sbjct: 2237 PPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIR 2296
Query: 112 E----CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDC 167
+ + CR ++ EC C G P + C +++C HG
Sbjct: 2297 QGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGS- 2355
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN 227
GYT RDVDEC +C +G C N G++ CHC G+
Sbjct: 2356 -------------GYTAEG---RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDAT 2399
Query: 228 -NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C+D++EC + C C+NT GSF C C GY L DGR C+D+DEC H C
Sbjct: 2400 ATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNC- 2457
Query: 287 RDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVC-AGGECRNFNGGYVCECP 345
C NT G + C C G+ + C D DEC P C A G C N G + CEC
Sbjct: 2458 ---QFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECH 2514
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
G+ + C D + C RC QL C C +G +C
Sbjct: 2515 QGFTLVSSGHGCEDVNE--CDGPH---RCQHGCQNQLGGYRCSCPQGFTQHSQWAQCV-- 2567
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
D +EC + P C C NT G FRC CP G+
Sbjct: 2568 --------------------DENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGG 2607
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV 508
C D DECA C +C+NT GG+ C C G+ + CV
Sbjct: 2608 CQDVDECAGRRGPCSY-SCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 180 bits (438), Expect = 2e-44
Identities = 99/242 (40%), Positives = 122/242 (50%), Gaps = 22/242 (9%)
Query: 414 CQGGMGRPNLTQ----DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
CQ G P+ T D+DEC P C C NT GSF C CP GY+L DG +C D
Sbjct: 2390 CQAGY-TPDATATTCLDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDL 2447
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNT 527
DEC C C NT G + C+C PGFTQ Q C D DEC+ C CHNT
Sbjct: 2448 DECTSRQHNC-QFLCVNTVGAFTCRCPPGFTQH-HQACFDNDECSAQPGPCGAHGHCHNT 2505
Query: 528 AGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQ 587
GSFRC C G+ + + G C D++EC P C H C+N +G Y C CP+G+ + S Q
Sbjct: 2506 PGSFRCECHQGFTLVSSGHGCEDVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHS--Q 2562
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE------PSEDGTDCIDRRTG 641
++ C D NEC C C NT G F C C +GF+ +D +C RR G
Sbjct: 2563 WAQ--CVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRR-G 2619
Query: 642 TC 643
C
Sbjct: 2620 PC 2621
Score = 98.7 bits (235), Expect = 8e-20
Identities = 116/418 (27%), Positives = 158/418 (37%), Gaps = 56/418 (13%)
Query: 250 NTVGS-FRCECAPGYTLTADGRNCRDVDECDELPHPCGRD--GNPS-CTNTNGGYECSCG 305
N GS F C PG+ T GR+ V C CG P+ CT +G SCG
Sbjct: 58 NVCGSRFHAYCCPGWR-TFPGRSQCVVPICRRA---CGEGFCSQPNLCTCADGTLAPSCG 113
Query: 306 AG-WKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCE--CPAGWR-FDKTAAVCV--- 358
C++ C+ +C G G +C+ C G R CV
Sbjct: 114 VSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCACVYGF 173
Query: 359 -------DERKELCYDEWEAGRC-HRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
D R C+ + C H+ L + CC + G AWG CE CPA
Sbjct: 174 MGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHP-- 231
Query: 411 MRICQGGMGRPNL----TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
C+ G PN+ QD+DEC+ P +C GG CVN GSF C CP G+ L+ +C
Sbjct: 232 ---CRRGF-IPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAAC 287
Query: 467 VDADECALDPRICGNGTCSNTRGGY----ECQCSPG--FTQGPDQTCVDVDECAEGRASC 520
D A + G G C+ G+ +C C G + GP E + C
Sbjct: 288 EDYRAGACFSVLFG-GRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLC 346
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPE-G 579
R G P G G + + R+ PH GS P G
Sbjct: 347 AQRLPLLPGH-----P-GLFPGLLGFGSNGMGPPLGPARLNPH------GSDARGIPSLG 394
Query: 580 YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
++ + N DI C +LC G C+ T S+ C+C+ G+ G +CID
Sbjct: 395 PGNSNIGTATLNQTIDI--CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRG-ECID 449
Score = 98.3 bits (234), Expect = 1e-19
Identities = 46/113 (40%), Positives = 57/113 (50%), Gaps = 9/113 (7%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL--CHNT 798
D+DEC + C G F C C PG+ + C D DEC+ +P PC CHNT
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNT 2505
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
GS+ C C G+ L G C DV+EC+ H CQ C N G Y CSC G+
Sbjct: 2506 PGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHGCQNQLGGYRCSCPQGF 2557
Score = 97.9 bits (233), Expect = 1e-19
Identities = 51/124 (41%), Positives = 61/124 (49%), Gaps = 11/124 (8%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHN 797
D DECA LC APG +RC C G+ P + C DVDECA C N
Sbjct: 1362 DRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCEN 1421
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRG 855
G + C+C GYELD G NC D++EC + +C NT GSY CSC +E G
Sbjct: 1422 LPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481
Query: 856 DACV 859
CV
Sbjct: 1482 VGCV 1485
Score = 94.3 bits (224), Expect = 2e-18
Identities = 46/120 (38%), Positives = 58/120 (48%), Gaps = 10/120 (8%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ-LCH 796
DVDECA P LC G ++C C PG+ G C D+DEC++ C C
Sbjct: 1071 DVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCV 1130
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
N G++ C C G++ D C D++EC C C NTEGSY CSC GY D
Sbjct: 1131 NVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPD 1190
Score = 89.0 bits (211), Expect = 6e-17
Identities = 39/103 (37%), Positives = 54/103 (52%), Gaps = 4/103 (3%)
Query: 761 GRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDEDGA 817
G +RC C G+ + C D +ECA+ PP C C NT G + C+C +G++ D+
Sbjct: 2547 GGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALG 2606
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
C+DVDEC C C+NT G + C C GY + G CV
Sbjct: 2607 GCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 84.2 bits (199), Expect = 2e-15
Identities = 49/125 (39%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQ--LC 795
DVDEC P +C G F C C GY R C+DVDEC V CD C
Sbjct: 1238 DVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASC 1297
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEK 853
N GS+ C C G+ DG C D+DEC H C C N GSY C+C G+
Sbjct: 1298 LNIPGSFSCRCLPGWV--GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355
Query: 854 RGDAC 858
G C
Sbjct: 1356 DGFFC 1360
Score = 80.6 bits (190), Expect = 2e-14
Identities = 44/117 (37%), Positives = 53/117 (45%), Gaps = 12/117 (10%)
Query: 747 DVDECAAIPGLCA--------PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCH 796
D DEC+A PG C PG FRC C G+ +G C DV+EC P C C
Sbjct: 2485 DNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHGCQ 2543
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYE 852
N G Y C C G+ A C D +EC TC C NT G + C C G++
Sbjct: 2544 NQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFD 2600
Score = 73.3 bits (172), Expect = 3e-12
Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 7/95 (7%)
Query: 15 GVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIM 74
G+ TK LCC +VG AWG PCE CP + P + G N T + +DEC +
Sbjct: 202 GLVCTKALCCATVGRAWGLPCELCPAQPHPC-------RRGFIPNIHTGACQDVDECQAV 254
Query: 75 PQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
P LC+ G+C + F C C G+ ++S C D
Sbjct: 255 PGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 70.9 bits (166), Expect = 2e-11
Identities = 45/120 (37%), Positives = 58/120 (48%), Gaps = 12/120 (10%)
Query: 751 CAAIPGLCAPGRFRCVCG---PGYRP---AGEVCADVDECAVRPPPC-DQLCHNTDGSYD 803
C A P +P ++ +CG PG+ G+ D+DEC P C + +C N GS+
Sbjct: 1688 CEACPTPISPD-YQILCGNQAPGFLTDIHTGKPL-DIDECGEIPAICANGICINQIGSFR 1745
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE-KRGDACVG 860
C C G+ + C DVDEC CQQ C N GSY C C GY+ G ACVG
Sbjct: 1746 CECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVG 1805
Score = 50.4 bits (115), Expect = 3e-05
Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 32/149 (21%)
Query: 743 DVFADVDECAAIP---GLCA--PGRFRCVCGPGYR--PAGEVCADVDE--C--AVRPPPC 791
++ DVDEC + P G+C G + C CGPG R P+G C D + C ++ C
Sbjct: 762 EICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRC 821
Query: 792 DQLCHNTDGSYDCLCRTGY---------ELDE---------DGANCRDVDECERDTHTCQ 833
+ +C G E+D G C DV+ECE C
Sbjct: 822 EVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCP 881
Query: 834 Q-ICSNTEGSYECSCEDG--YEKRGDACV 859
C NT GS+ C C +G + G CV
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCV 910
Score = 48.0 bits (109), Expect = 1e-04
Identities = 57/195 (29%), Positives = 74/195 (37%), Gaps = 34/195 (17%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
GTC G C C GY T +C C G C +C+ G C C G
Sbjct: 128 GTCR----GASCLCQKGY----TGTVCGQ-PICDRG---CHNGGRCI---GPNRCACVYG 172
Query: 141 YRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRP 200
+ + P +CE D R G C +G C+ + L VC C+
Sbjct: 173 F-MGP---QCER-----DYRT---GPCFGQVGPEGCQ----HQLTGLVCTKALCCATVGR 216
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCEC 259
CE P A C GF + C DV+EC+ +C+ G C N VGSF C C
Sbjct: 217 AW-GLPCELCP-AQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRC 274
Query: 260 APGYTLTADGRNCRD 274
G+ L+ C D
Sbjct: 275 PVGHRLSDSSAACED 289
Score = 38.7 bits (86), Expect = 0.087
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGY 851
CR G+ + C+DVDEC+ CQ C N GS+ C C G+
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGH 278
>AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 728 bits (1799), Expect = 0.0
Identities = 355/869 (40%), Positives = 460/869 (52%), Gaps = 64/869 (7%)
Query: 9 SCAGAVGVPQTKYLCCCS--VGHAWGAPCEACPPRGSPAHTALCGEK-PGEYINPVTNET 65
+C + T+ +CCCS +G AW PCEACP SP + LCG + PG + T +
Sbjct: 1660 TCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKP 1719
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ 125
IDEC +P +C G C + F+C C G+ +++ C DVDEC PC+ A
Sbjct: 1720 LDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCECKPGY-- 182
C+N+PG++ C+C GY+L+P C +EC + +C HGDC +T GSY C C G+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPG-GACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQA 1838
Query: 183 TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE-GGM 241
+ + +C D+DEC R +P C NGTC+N+ G+Y C C GF N DCVD +EC G
Sbjct: 1839 SADQTLCMDIDECDR-QP-CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 242 VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
VCR G C NT GSF C C G+ LTADG+NC D +EC L C G +C N G +
Sbjct: 1897 VCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTC-LPG--TCQNLEGSFR 1953
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER 361
C C G+++ C+D DEC E P +C G C N G + C CP G+ C D R
Sbjct: 1954 CICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTR 2013
Query: 362 KELCYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMRICQGGMG 419
+ C+ +EAG+C + + CCCS+ G WG CE CP SA F +C G G
Sbjct: 2014 QSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHG 2073
Query: 420 R----PNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
+ +D++EC P VC G CVNTDGSFRCECP GY L G++CVD DEC++
Sbjct: 2074 AVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG 2133
Query: 476 PRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
CG GTC+N GG+EC C+ GF G TC D+DEC+ C FRCHNT GS+ CTC
Sbjct: 2134 -HPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTC 2192
Query: 536 PYGYAVAADGVHCRDIDECVQEPRVCPHA----CENVVGSYICKCPEGYRRTSAPQDSEN 591
P GY + DG CRD+DEC + C HA C+N++G++ C CP G R P E
Sbjct: 2193 PAGYTLREDGAMCRDVDECADGQQDC-HARGMECKNLIGTFACVCPPGMR--PLPGSGE- 2248
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGR 651
C D NEC Q DLC G C+NT GSF CDCD GF+PS T+C D R G C+ ++
Sbjct: 2249 GCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTM 2308
Query: 652 CEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDL 711
C VT+A+CCC G WG CELCP PG+ A L
Sbjct: 2309 CR------------------SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKL 2350
Query: 712 CTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCAPGRFRCVCGPGY 771
C + A + CA + + G FRC C GY
Sbjct: 2351 CP--------------HGSGYTAEGRDVDECRMLAHL--CAHGECINSLGSFRCHCQAGY 2394
Query: 772 RP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDT 829
P C D+DEC+ P PC LC NT GS+ C C GY L+EDG C+D+DEC
Sbjct: 2395 TPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQ 2454
Query: 830 HTCQQICSNTEGSYECSCEDGYEKRGDAC 858
H CQ +C NT G++ C C G+ + AC
Sbjct: 2455 HNCQFLCVNTVGAFTCRCPPGFTQHHQAC 2483
Score = 458 bits (1129), Expect = e-128
Identities = 268/748 (35%), Positives = 343/748 (45%), Gaps = 83/748 (11%)
Query: 151 EDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTLR-ENVCRDVDECSRPRPVCRNGTCE 208
+ +D C +C +G C T SYRCEC GYT C DVDEC+ C +G C
Sbjct: 407 QTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSP--CHHGDCV 464
Query: 209 NLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTA 267
N+PG Y C C GF+A P CVDV+EC G +C GRC NT GSF+C C G+ L+
Sbjct: 465 NIPGTYHCQCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSP 524
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELP 325
DG+NC D +EC C N C N +G + C C G+ L G C+D DEC + P
Sbjct: 525 DGKNCVDHNEC-ATSTMCV---NGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDEC-QTP 579
Query: 326 YVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER-KELCYDEWEAGRCHRARPLQLAR 384
+C G C N G + C+C G VCVD + CY E G C R P + +
Sbjct: 580 GICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTK 639
Query: 385 PECCCSE-GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCV 443
ECCC+ +G C+ CPA +SAEF +C G+G +D++EC + P+VC G C
Sbjct: 640 SECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCE 699
Query: 444 NTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
N GS+RC C GY G C D DECAL+ +C NG C N+ G Y C C PGF
Sbjct: 700 NLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQ 759
Query: 504 D-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP 562
D + C DVDEC + C N AGS+ C C G + G C D + ++
Sbjct: 760 DTEICKDVDECLSS-PCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQE 818
Query: 563 HACE-NVVGSYI---CKCPEGYRRTSAPQDSE--------------NACEDINECEEQED 604
CE N+ G+ + C G S + E C+D+NECE
Sbjct: 819 SRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPG 878
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXX 664
+C G C+NT GSF C+C G G C+D R C+ C
Sbjct: 879 VCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDEC------------ 926
Query: 665 XXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXX 724
G CCC++GA WG ECE CP P S LC
Sbjct: 927 --------GVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCP----------- 967
Query: 725 XXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLC-------APGRFRCVCGPGYRPAGEV 777
+ DV+EC PGLC G F C C G+ +
Sbjct: 968 ----RGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQE 1023
Query: 778 --CADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD-EDGANCRDVDECERDTHTCQ 833
C D+DEC + P C Q C NT GS++C C GYE NC DVDEC RD C+
Sbjct: 1024 RNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCR 1083
Query: 834 -QICSNTEGSYECSCEDGYE--KRGDAC 858
C+NT+GSY+C C G+E +G AC
Sbjct: 1084 GGTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Score = 442 bits (1090), Expect = e-123
Identities = 286/830 (34%), Positives = 359/830 (43%), Gaps = 101/830 (12%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+DEC P LC+ GTC +T ++C C G+E C D+DECS C QCV
Sbjct: 1072 VDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH-GQCV 1130
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
N+ GAF+C C G++ TP C D++EC Q C NT GSYRC C GY+L +
Sbjct: 1131 NVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPD 1190
Query: 188 --VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCR 244
C DVDEC VC G C N+PG + C C DGF A P+ CVDV+EC +C
Sbjct: 1191 GRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICL 1250
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
+G C NT GSF C C GY + C DVDEC+ H C D + SC N G + C C
Sbjct: 1251 HGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNC--DSHASCLNIPGSFSCRC 1308
Query: 305 GAGWKLVGRRCVDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
GW G C D DEC + C+ G+C N G Y C C G+ D DE E
Sbjct: 1309 LPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAE 1368
Query: 364 --------LCYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMR- 412
C + RC C + A G C + R
Sbjct: 1369 NVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRC 1428
Query: 413 ICQGGM----GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
IC GG G N T D++EC P C+ G C+NT GS+ C CP + L P G+ CVD
Sbjct: 1429 ICNGGYELDRGGGNCT-DINEC-ADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVD 1486
Query: 469 --ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRA---SCTFR 523
A C L+ G+ G C G C C+ GRA C
Sbjct: 1487 TRAGNCFLETHDRGDS-------GISCSAEIGVGVTRASCC-----CSLGRAWGNPCELC 1534
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHC--RDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
+R CP G + + DIDEC + P +C C N GS+ C+CP GY
Sbjct: 1535 PMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGY 1594
Query: 581 RRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRT 640
+ + CEDI+EC +C G C NT G++ C C A + G +C+D R
Sbjct: 1595 HLS----EHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRK 1650
Query: 641 GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCT--LGAAWGSECE 698
C+R +G C+ E +VT+ CCC+ +G AW CE
Sbjct: 1651 SVCFRH-YNGTCQNELAF--------------------NVTRKMCCCSYNIGQAWNRPCE 1689
Query: 699 LCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLC 758
CP P SP LC N P D+DEC IP +C
Sbjct: 1690 ACPTPISPDYQILCG--NQAPGFLTDIHTGKP---------------LDIDECGEIPAIC 1732
Query: 759 AP-------GRFRCVCGPG--YRPAGEVCADVDECAVRPPPCDQL--CHNTDGSYDCLCR 807
A G FRC C G Y C DVDEC R PC Q C N GSY C C
Sbjct: 1733 ANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCT 1792
Query: 808 TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
GY+L GA C +EC + C C +TEGSY C C G++ D
Sbjct: 1793 RGYKLSPGGA-CVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASAD 1841
Score = 430 bits (1060), Expect = e-120
Identities = 232/592 (39%), Positives = 291/592 (49%), Gaps = 47/592 (7%)
Query: 1 MEWNEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
+ W+E++ C + +CCCS+G WG CEACP S +LC G
Sbjct: 919 LRWDEDE--CGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRD 976
Query: 61 VTNET---KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGR 117
+ K ++EC + P LC GTC +T F C C G+ D C D+DEC
Sbjct: 977 FLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISP 1036
Query: 118 PPCRGMAQCVNLPGAFECRCPPGYRLTPSL-DECEDVDECG-DQRICDHGDCRNTIGSYR 175
C G CVN PG+FEC C PGY L C DVDEC D +C G C NT GSY+
Sbjct: 1037 DLC-GQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYK 1095
Query: 176 CECKPGY--TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVD 232
C+C PG+ T + C D+DECS +C +G C N+ GA+ C C GF++ P+ CVD
Sbjct: 1096 CQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVD 1155
Query: 233 VNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
+NECR C + C NT GS+RC C GY+L DGR C DVDEC+E P C +
Sbjct: 1156 INECRVQNGGC-DVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQG---H 1211
Query: 293 CTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRF 350
CTN GG+ C C G+ R CVD DEC P++C G+C N G +VC C G+
Sbjct: 1212 CTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMV 1271
Query: 351 DKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
K A C D DE E G H C A+ C P S
Sbjct: 1272 RKGATGCSD------VDECEVGG-HN------------CDSHAS----CLNIPGSFSC-- 1306
Query: 411 MRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
R G +G DLDEC + C G C+N GS+RC C G+ A DG C D
Sbjct: 1307 -RCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCEDR 1363
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTA 528
DECA + +C NG C N GGY C+C GF D + C DVDECA+G C N
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLP 1423
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGY 580
G FRC C GY + G +C DI+EC C N GSY+C CP+ +
Sbjct: 1424 GMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDF 1475
Score = 409 bits (1007), Expect = e-113
Identities = 300/917 (32%), Positives = 373/917 (40%), Gaps = 98/917 (10%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPID 69
C VG Q C V +PC P T C PG P +D
Sbjct: 433 CECNVGYTQDVRGECIDVDECTSSPCHHGDCVNIPG-TYHCQCYPGFQATPTRQACVDVD 491
Query: 70 ECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
EC + LC G C +T FQC C+ G+E C D +EC+ G+ C+N
Sbjct: 492 ECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGV--CLNE 549
Query: 130 PGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN-- 187
G+F C C PG+ L P C D+DEC IC +G C NT GS+RC+C G + +
Sbjct: 550 DGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGR 609
Query: 188 VCRDVD------------ECSRPRP--VCRNGTCENLPG------AYLCHCDDG--FKA- 224
VC D C+RP P V ++ C P LC + F+A
Sbjct: 610 VCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQAL 669
Query: 225 -----GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECD 279
G D D+NEC VC NG C N GS+RC C GY A G++C DVDEC
Sbjct: 670 CSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECA 729
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFN 337
C N C N+ G Y CSC G+ C D DEC P C G CRN
Sbjct: 730 LNSLLCD---NGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLA 784
Query: 338 GGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGR 397
G Y C+C G R D + C+D K C+ + + RC R ECC + GAAWG
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGS 844
Query: 398 YCERCPAPDSAEFMRICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPD 455
CERC E C G R D++EC P VC GRCVNT GSFRCECP+
Sbjct: 845 PCERC------EIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPE 898
Query: 456 GYVLAPDGLSCVDA--DECAL--DPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDV 510
G +L G CVD + C L D CG R C CS G G + + C D
Sbjct: 899 GLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDV-CCCSIGAVWGVECEACPD- 956
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH-ACENVV 569
E E + C + F P+ +D++EC P +C H C N V
Sbjct: 957 PESLEFASLCPRGLGFASRDFLSGRPF----------YKDVNECKVFPGLCTHGTCRNTV 1006
Query: 570 GSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP- 628
GS+ C C G+ A E C DI+EC DLC G C+NT GSF C+C G+E
Sbjct: 1007 GSFHCACAGGF----ALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESG 1062
Query: 629 ----------SEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXG 678
E D + R GTC + S +C+ G
Sbjct: 1063 FMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDG 1122
Query: 679 HVTKAQCCCTLGAAWGS-ECELCPAPGSPARLDL--CTAVNLTPXXXXXXXXXXXXXXXX 735
QC +GA S P +D+ C N
Sbjct: 1123 LCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCG 1182
Query: 736 XXXXXXLD--VFADVDECAAIPGLC-------APGRFRCVCGPGY--RPAGEVCADVDEC 784
D ADVDEC P +C PG RC+C G+ P C DVDEC
Sbjct: 1183 QGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDEC 1242
Query: 785 AVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEG 841
+ P C C NT GS+ C C+ GY + + C DVDECE H C C N G
Sbjct: 1243 DLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPG 1302
Query: 842 SYECSCEDGYEKRGDAC 858
S+ C C G+ G C
Sbjct: 1303 SFSCRCLPGWVGDGFEC 1319
Score = 405 bits (996), Expect = e-112
Identities = 224/611 (36%), Positives = 293/611 (47%), Gaps = 53/611 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDE--------------- 112
IDEC P LC GTC ++P FQC C G+ + H C D +
Sbjct: 1970 IDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVP 2029
Query: 113 ---------CSWGRPPCRGMAQ-CVNLP----GAFECRCPPGYRLTPSLDEC-EDVDECG 157
C + P G C P AF+ CP G+ P D+ EDV+EC
Sbjct: 2030 KAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECA 2089
Query: 158 DQR-ICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAY 214
+ +C +G C NT GS+RCEC GY+L C D DECS P C GTC N+ G +
Sbjct: 2090 ENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP-CGQGTCTNVIGGF 2148
Query: 215 LCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRD 274
C C DGF+ G C D++EC ++C RC NT GS+ C C GYTL DG CRD
Sbjct: 2149 ECACADGFEPGLMMTCEDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Query: 275 VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV---GRRCVDRDECKELPYVCAGG 331
VDEC + C G C N G + C C G + + G C D +EC P +C G
Sbjct: 2208 VDECADGQQDCHARGM-ECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNG 2266
Query: 332 ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLA--RPECCC 389
C N G + C+C G++ T C D R+ C+ E C A R ECCC
Sbjct: 2267 RCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCC 2326
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
G WG CE CP P ++ + ++C G G +D+DECR+ +C G C+N+ GSF
Sbjct: 2327 GGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSF 2386
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCV 508
RC C GY +C+D DEC+ P+ C C NT+G + C C G+ D +TC
Sbjct: 2387 RCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCK 2445
Query: 509 DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC-PHA-CE 566
D+DEC + +C F C NT G+F C CP G+ C D DEC +P C H C
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQA--CFDNDECSAQPGPCGAHGHCH 2503
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
N GS+ C+C +G+ S S + CED+NEC+ C G C N G + C C GF
Sbjct: 2504 NTPGSFRCECHQGFTLVS----SGHGCEDVNECDGPH-RCQHG-CQNQLGGYRCSCPQGF 2557
Query: 627 EPSEDGTDCID 637
C+D
Sbjct: 2558 TQHSQWAQCVD 2568
Score = 395 bits (972), Expect = e-109
Identities = 287/876 (32%), Positives = 377/876 (43%), Gaps = 134/876 (15%)
Query: 21 YLCCCSVGHAW---GAPCEACPPRGSPAH--TALCGEKPGEYIN--PVTNETKP--IDEC 71
+ C C+ G+ G C P + +C PG Y+ P E P +
Sbjct: 1426 FRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCV 1485
Query: 72 DIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG 131
D C T +G C + G S C + +WG P C + N
Sbjct: 1486 DTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCC-SLGR-AWGNP-CE-LCPMANTT- 1540
Query: 132 AFECRCPPGYRLTPSLDEC--EDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTLREN- 187
+ CP G P+ ED+DEC + +C GDC NT GS++CEC PGY L E+
Sbjct: 1541 EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHT 1600
Query: 188 -VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF-KAGPNNDCVDVNECREGGMVC-- 243
+C D+DECS +C GTC N G Y C C + + N+C+D+ + VC
Sbjct: 1601 RICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKS-----VCFR 1655
Query: 244 -RNGRCRNTVGS--FRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGY 300
NG C+N + R C Y + C+ P P D C N G+
Sbjct: 1656 HYNGTCQNELAFNVTRKMCCCSYNIGQAWNR-----PCEACPTPISPDYQILCGNQAPGF 1710
Query: 301 ECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
G L D DEC E+P +CA G C N G + CECPAG+ ++ C D
Sbjct: 1711 LTDIHTGKPL------DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACED- 1763
Query: 361 RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG--M 418
DE + R P Q +C G+ RC ++ GG +
Sbjct: 1764 -----VDECGS----RESPCQ-QNADCINIPGSY------RCKCTRG---YKLSPGGACV 1804
Query: 419 GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRI 478
GR +ECR P+VC G C++T+GS+ C C G+ + D C+D DEC P
Sbjct: 1805 GR-------NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQP-- 1855
Query: 479 CGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAE--GRASCTF-RCHNTAGSFRCTC 535
CGNGTC N G Y C C PGF + CVD DEC G+ C F C NTAGSF C C
Sbjct: 1856 CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQV-CRFGHCLNTAGSFHCLC 1914
Query: 536 PYGYAVAADGVHCRDIDECVQEPRVC-PHACENVVGSYICKCPEGYRRTSAPQDSENACE 594
G+ + ADG +C D +EC+ C P C+N+ GS+ C CP G+ Q + C
Sbjct: 1915 QDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGF------QVQSDHCI 1968
Query: 595 DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEP 654
DI+EC E+ +LC G C N+ GSF C C GF S++G C D R C+ +G+C
Sbjct: 1969 DIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSV 2028
Query: 655 EXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTL--GAAWGSECELCPAPGSPARLDLC 712
+ TK +CCC+ G WG CELCP GS A +LC
Sbjct: 2029 PKAF--------------------NTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELC 2068
Query: 713 TAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCA-------PGRFRC 765
P D DV+ECA PG+C G FRC
Sbjct: 2069 ------PFGHGAVPGPD-------------DSREDVNECAENPGVCTNGVCVNTDGSFRC 2109
Query: 766 VCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
C GY G C D DEC+V P C N G ++C C G+E C D+D
Sbjct: 2110 ECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLM-MTCEDID 2168
Query: 824 ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 859
EC + C C NTEGSY C+C GY R D +
Sbjct: 2169 ECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAM 2204
Score = 380 bits (935), Expect = e-104
Identities = 219/596 (36%), Positives = 284/596 (47%), Gaps = 43/596 (7%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
CG+ G + P +DEC+ P++C G C + P G +C C G+ C D
Sbjct: 1181 CGQ--GYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVD 1238
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC--GDQRICDHGDC 167
VDEC C C N G+F C C GY + C DVDEC G H C
Sbjct: 1239 VDECDLNPHICLH-GDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASC 1297
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGP 226
N GS+ C C PG+ C D+DEC C G C N+PG+Y C C GF AG
Sbjct: 1298 LNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF-AGD 1356
Query: 227 NNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C D +EC E +C NG+C N G +RCEC G+ T D R C+DVDEC + + C
Sbjct: 1357 GFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ-GNLCA 1415
Query: 287 RDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
SC N G + C C G++L G C D +EC + P C G C N G Y+C C
Sbjct: 1416 FG---SCENLPGMFRCICNGGYELDRGGGNCTDINECAD-PVNCINGVCINTPGSYLCSC 1471
Query: 345 PAGWRFDKTAAVCVDERKELCY----DEWEAG-RCHRARPLQLARPECCCSEGAAWGRYC 399
P + + + CVD R C+ D ++G C + + R CCCS G AWG C
Sbjct: 1472 PQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPC 1531
Query: 400 ERCPAPDSAEFMRICQGGMG-RPN----LTQDLDECRVRPDVCVGGRCVNTDGSFRCECP 454
E CP ++ E+ +C GG G +PN + +D+DEC+ P +C GG CVNT GSF+CECP
Sbjct: 1532 ELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECP 1591
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ-GPDQTCVDVDEC 513
GY L+ C D DEC+ ICG GTC NT G Y C C + Q C+D+
Sbjct: 1592 PGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDM--- 1648
Query: 514 AEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVG-S 571
R S FR +N C + V C +I + P C AC +
Sbjct: 1649 ---RKSVCFRHYNGT----CQNELAFNVTRKMCCCSYNIGQAWNRP--C-EACPTPISPD 1698
Query: 572 YICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
Y C G + D DI+EC E +C+ G+CIN GSF C+C AGF
Sbjct: 1699 YQILC--GNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGF 1752
Score = 372 bits (914), Expect = e-102
Identities = 242/661 (36%), Positives = 302/661 (45%), Gaps = 88/661 (13%)
Query: 11 AGAVGVPQ----TKYLCCCSV--GHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNE 64
AG VP+ TK CCCS G WG PCE CP GS A LC G P +
Sbjct: 2023 AGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGP-DDS 2081
Query: 65 TKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+ ++EC P +C G C +T F+C C GY D T C D DECS G P C G
Sbjct: 2082 REDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP-C-GQG 2139
Query: 125 QCVNLPGAFECRCPPGYRLTPSLD-ECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYT 183
C N+ G FEC C G+ P L CED+DEC + C NT GSY C C GYT
Sbjct: 2140 TCTNVIGGFECACADGFE--PGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYT 2197
Query: 184 LREN--VCRDVDECSRPRPVC--RNGTCENLPGAYLCHCDDGFKA--GPNNDCVDVNECR 237
LRE+ +CRDVDEC+ + C R C+NL G + C C G + G C D NEC
Sbjct: 2198 LREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECH 2257
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE-----------CDELPHP-- 284
+C NGRC NT GSFRC+C G+ + C D+ + C L
Sbjct: 2258 AQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSE 2317
Query: 285 --------CG--RDGNPSCTNT----NGGYE--CSCGAGWKLVGRRCVDRDECKELPYVC 328
CG R P C Y C G+G+ GR D DEC+ L ++C
Sbjct: 2318 AVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGR---DVDECRMLAHLC 2374
Query: 329 AGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECC 388
A GEC N G + C C AG+ D TA C+D DE C Q+ +P C
Sbjct: 2375 AHGECINSLGSFRCHCQAGYTPDATATTCLD------MDE-----CS-----QVPKP-CT 2417
Query: 389 CSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGS 448
G + CP E + G +DLDEC R C CVNT G+
Sbjct: 2418 FLCKNTKGSFLCSCPRGYLLE-----EDG----RTCKDLDECTSRQHNCQF-LCVNTVGA 2467
Query: 449 FRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQ-GPDQT 506
F C CP G+ +C D DEC+ P CG +G C NT G + C+C GFT
Sbjct: 2468 FTCRCPPGFTQHHQ--ACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHG 2525
Query: 507 CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-C 565
C DV+EC +G C C N G +RC+CP G+ + C D +EC P C A C
Sbjct: 2526 CEDVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASC 2584
Query: 566 ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
N +G + C CP G+ A C+D++EC + CS C NT G FLC C G
Sbjct: 2585 RNTLGGFRCVCPSGFDFDQAL----GGCQDVDECAGRRGPCSYS-CANTPGGFLCGCPQG 2639
Query: 626 F 626
+
Sbjct: 2640 Y 2640
Score = 356 bits (876), Expect = 2e-97
Identities = 213/603 (35%), Positives = 278/603 (46%), Gaps = 41/603 (6%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC LC G C + P G++C C+ G++ C+DVDEC+ G G C N
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFG--SCEN 1421
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENV 188
LPG F C C GY L C D++EC D C +G C NT GSY C C + L +
Sbjct: 1422 LPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481
Query: 189 CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC 248
VD + C T + C + G + C + R G C
Sbjct: 1482 VGCVDTRAGN---CFLETHDRGDSGISCSAEIGVGVTRASCCCSLG--RAWGNPCELCPM 1536
Query: 249 RNTVGSFRCECAPGYTLTADGRNC--RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
NT +R C G + D+DEC ELP C + G+ C NT G ++C C
Sbjct: 1537 ANTT-EYRTLCPGGEGFQPNRITVILEDIDECQELPGLC-QGGD--CVNTFGSFQCECPP 1592
Query: 307 GWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKEL 364
G+ L R C D DEC +C G C N G Y C CPA + C+D RK +
Sbjct: 1593 GYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSV 1652
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMRICQGGMGRPN 422
C+ + G C + R CCCS G AW R CE CP P S ++ +C G
Sbjct: 1653 CFRHYN-GTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILC-GNQAPGF 1710
Query: 423 LTQ-------DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
LT D+DEC P +C G C+N GSFRCECP G+ L+C D DEC
Sbjct: 1711 LTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSR 1770
Query: 476 PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRC 533
C N C N G Y C+C+ G+ P CV +EC E C+ C +T GS+ C
Sbjct: 1771 ESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMC 1830
Query: 534 TCPYGYAVAADGVHCRDIDECVQEPRVCPH-ACENVVGSYICKCPEGYRRTSAPQDSENA 592
C G+ +AD C DIDEC ++P C + C+N++GSY C C G+ T
Sbjct: 1831 LCHRGFQASADQTLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGFVVT-----HNGD 1883
Query: 593 CEDINECEE-QEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGR 651
C D +EC +C G C+NT GSF C C GFE + DG +C+D T C ++G
Sbjct: 1884 CVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVD--TNECLS--LAGT 1939
Query: 652 CEP 654
C P
Sbjct: 1940 CLP 1942
Score = 343 bits (842), Expect = 2e-93
Identities = 209/655 (31%), Positives = 294/655 (44%), Gaps = 59/655 (9%)
Query: 9 SCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPI 68
SC+ +GV T+ CCCS+G AWG PCE CP + + LC G N +T + I
Sbjct: 1505 SCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDI 1564
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC +P LC+ G C +T FQC C GY + +C D+DECS C G C N
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGTCYN 1623
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTI--GSYRCECKPGYTLRE 186
G + C CP Y + C D+ + R +G C+N + R C Y + +
Sbjct: 1624 TLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHY-NGTCQNELAFNVTRKMCCCSYNIGQ 1682
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
R + C P C N +L G +D++EC E +C NG
Sbjct: 1683 AWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTG-------KPLDIDECGEIPAICANG 1735
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
C N +GSFRCEC G+ + C DVDEC PC + N C N G Y C C
Sbjct: 1736 ICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQ--NADCINIPGSYRCKCTR 1793
Query: 307 GWKL-VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
G+KL G CV R+EC+E+P VC+ G+C + G Y+C C G++ +C+D
Sbjct: 1794 GYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMD------ 1847
Query: 366 YDEWEAGRCHRARPLQ-LARPECCCSEG----------------AAWGRYCERCPAPDSA 408
DE + C + C C G G+ C ++A
Sbjct: 1848 IDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTA 1907
Query: 409 -EFMRICQGGM---GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
F +CQ G D +EC C+ G C N +GSFRC CP G+ + D
Sbjct: 1908 GSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSD-- 1965
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
C+D DEC+ +P +C GTC+N+ G ++C C PGF + C + R S C
Sbjct: 1966 HCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG-----HRCFDTRQSF---C 2017
Query: 525 HNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEP-RVCPHACENVVGSYICKCPEGYRR 582
+ +C+ P + C + E +P +CP + ++ CP G+
Sbjct: 2018 FTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCP---QEGSAAFQELCPFGHGA 2074
Query: 583 TSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
P DS ED+NEC E +C+ GVC+NTDGSF C+C G+ G +C+D
Sbjct: 2075 VPGPDDSR---EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVD 2126
Score = 337 bits (828), Expect = 1e-91
Identities = 216/646 (33%), Positives = 295/646 (45%), Gaps = 65/646 (10%)
Query: 23 CCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGT 82
CC ++G AWG+PCE C PA G VT + ++EC+ P +C G
Sbjct: 834 CCATLGAAWGSPCERCEI--DPACARGFARMTG-----VTCDD--VNECESFPGVCPNGR 884
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDV--DEC--SWGRPPCRGMAQCVNLPGAFE---C 135
C +T F+C C G D + LC DV + C W C V LPG + C
Sbjct: 885 CVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECG-----VTLPGKYRMDVC 939
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDEC 195
C G + C D + +C G +G + G +DV+EC
Sbjct: 940 CCSIGAVWGVECEACPDPESLEFASLCPRG-----LGFASRDFLSGRPFY----KDVNEC 990
Query: 196 SRPRPVCRNGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRNGRCRNTVGS 254
+C +GTC N G++ C C GF +C D++ECR +C G C NT GS
Sbjct: 991 KVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGS 1050
Query: 255 FRCECAPGYTLTAD-GRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV-- 311
F CEC PGY +NC DVDEC P C R G +CTNT+G Y+C C G +L
Sbjct: 1051 FECECFPGYESGFMLMKNCMDVDECARDPLLC-RGG--TCTNTDGSYKCQCPPGHELTAK 1107
Query: 312 GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK--------- 362
G C D DEC +C G+C N G + C C AG++ CVD +
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCD 1167
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCS---EGAAWGRYCERCPAPDSAEFMR-ICQGG- 417
C + + RC + L C+ E R C++ + R +C G
Sbjct: 1168 VHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGF 1227
Query: 418 MGRPNLTQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
M P++ D+DEC + P +C+ G C NT GSF C C GY++ C D DEC +
Sbjct: 1228 MATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVG 1287
Query: 476 PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFR 532
C + +C N G + C+C PG+ G C D+DEC C+ R C N GS+R
Sbjct: 1288 GHNCDSHASCLNIPGSFSCRCLPGWV-GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYR 1346
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSEN 591
CTC G+A DG C D DEC + +C + C N G Y C+C G+ P +
Sbjct: 1347 CTCRQGFA--GDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFD----PTEDHR 1400
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
AC+D++EC Q +LC+ G C N G F C C+ G+E G +C D
Sbjct: 1401 ACQDVDEC-AQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTD 1445
Score = 329 bits (808), Expect = 3e-89
Identities = 239/714 (33%), Positives = 308/714 (43%), Gaps = 111/714 (15%)
Query: 21 YLCCCSVGHAWGAPCEACPPRGSPAHTAL------CGEKPGEYINPV---------TNET 65
Y C C++G+ GA + C A +L C PG Y T
Sbjct: 705 YRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEIC 764
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS-WGR---PPCR 121
K +DEC P C G C + + C C G D + C D + + W + C
Sbjct: 765 KDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE 822
Query: 122 GMAQ--------CVNLPGAF-----ECR----CPPGYRLTPSLDECEDVDECGD-QRICD 163
Q C L A+ C C G+ + C+DV+EC +C
Sbjct: 823 VNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVT-CDDVNECESFPGVCP 881
Query: 164 HGDCRNTIGSYRCECKPGYTLREN--VCRDV-----------DECSRPRP--------VC 202
+G C NT GS+RCEC G L + +C DV DEC P C
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCC 941
Query: 203 RNGT-----CENLPG------AYLCHCDDGFKA----GPNNDCVDVNECREGGMVCRNGR 247
G CE P A LC GF + DVNEC+ +C +G
Sbjct: 942 SIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT 1001
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
CRNTVGSF C CA G+ L A RNC D+DEC P CG+ +C NT G +EC C G
Sbjct: 1002 CRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG---TCVNTPGSFECECFPG 1058
Query: 308 WK---LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKE 363
++ ++ + C+D DEC P +C GG C N +G Y C+CP G C D +
Sbjct: 1059 YESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECS 1118
Query: 364 L---------CYDEWEAGRC--HRARPLQLARPECC-CSEGAAWGRYCE-RCPAPDSAEF 410
L C + A +C H R C +E C+ C + +
Sbjct: 1119 LSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYR 1178
Query: 411 MRICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
QG P+ D+DEC P VC G C N G RC C DG++ PD +CVD
Sbjct: 1179 CSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVD 1238
Query: 469 ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFR--CH 525
DEC L+P IC +G C NT+G + C C G+ T C DVDEC G +C C
Sbjct: 1239 VDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCL 1298
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECV-QEPRVCPHA-CENVVGSYICKCPEGYRRT 583
N GSF C C G+ DG C D+DECV QE R P C NV GSY C C +G+
Sbjct: 1299 NIPGSFSCRCLPGWV--GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGD 1356
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
CED +EC E DLC G C+N G + C+C+ GF+P+ED C D
Sbjct: 1357 GF------FCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 290 bits (711), Expect = 2e-77
Identities = 192/556 (34%), Positives = 250/556 (44%), Gaps = 83/556 (14%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC + C GTC + GF+C C G+E C D+DECS C +C N
Sbjct: 2128 DECSV-GHPCGQGTCTNVIGGFECACADGFE-PGLMMTCEDIDECSLNPLLCA--FRCHN 2183
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICD-HG-DCRNTIGSYRCECKPGYTLR 185
G++ C CP GY L C DVDEC D Q+ C G +C+N IG++ C C PG
Sbjct: 2184 TEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPL 2243
Query: 186 ENV---CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF------------KAGP---- 226
C D +EC +C NG C N G++ C CD+GF + GP
Sbjct: 2244 PGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAE 2303
Query: 227 -----------NNDCVDVNECREGGMVCRNGRCRNT----VGSFRCECAPGYTLTADGRN 271
+++ V EC GG RC ++R C G TA+GR
Sbjct: 2304 VLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGR- 2362
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK--LVGRRCVDRDECKELPYVCA 329
DVDEC L H C C N+ G + C C AG+ C+D DEC ++P C
Sbjct: 2363 --DVDECRMLAHLCAHG---ECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCT 2417
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C+N G ++C CP G+ ++ C D DE + R H + L C
Sbjct: 2418 F-LCKNTKGSFLCSCPRGYLLEEDGRTCKD------LDECTS-RQHNCQFL------CVN 2463
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGS 448
+ GA + RCP P + + C D DEC +P C G C NT GS
Sbjct: 2464 TVGA----FTCRCP-PGFTQHHQACF----------DNDECSAQPGPCGAHGHCHNTPGS 2508
Query: 449 FRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-C 507
FRCEC G+ L G C D +EC P C +G C N GGY C C GFTQ C
Sbjct: 2509 FRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQC 2566
Query: 508 VDVDECAEGRASC-TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
VD +ECA +C + C NT G FRC CP G+ C+D+DEC C ++C
Sbjct: 2567 VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYSCA 2626
Query: 567 NVVGSYICKCPEGYRR 582
N G ++C CP+GY R
Sbjct: 2627 NTPGGFLCGCPQGYFR 2642
Score = 290 bits (711), Expect = 2e-77
Identities = 195/525 (37%), Positives = 244/525 (46%), Gaps = 87/525 (16%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC--RGMAQ 125
IDEC + P LC CH+T + C C GY +CRDVDEC+ G+ C RGM +
Sbjct: 2167 IDECSLNPLLCA-FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGM-E 2224
Query: 126 CVNLPGAFECRCPPGYRLTPSLDE-CEDVDECGDQR-ICDHGDCRNTIGSYRCECKPGY- 182
C NL G F C CPPG R P E C D +EC Q +C +G C NT GS+RC+C G+
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 183 ---TLRE---------------NVCRDVDECS----RPRPVCRNGT-----CE--NLPG- 212
TL E +CR + S R C G CE LPG
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGT 2344
Query: 213 -AYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRN 271
AY C G +G + DV+ECR +C +G C N++GSFRC C GYT A
Sbjct: 2345 SAYRKLCPHG--SGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATT 2402
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCA 329
C D+DEC ++P PC C NT G + CSC G+ L GR C D DEC + C
Sbjct: 2403 CLDMDECSQVPKPC----TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQ 2458
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C N G + C CP G+ + + C+D E A+P C
Sbjct: 2459 F-LCVNTVGAFTCRCPPGFT----------QHHQACFDNDECS----------AQPGPCG 2497
Query: 390 SEGAAWGRYCERCPAPDSAEFMR---ICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTD 446
+ G +C P E + + G G +D++EC P C G C N
Sbjct: 2498 AHG-----HCHNTPGSFRCECHQGFTLVSSGHG----CEDVNECD-GPHRCQHG-CQNQL 2546
Query: 447 GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT 506
G +RC CP G+ CVD +ECAL P CG+ +C NT GG+ C C GF DQ
Sbjct: 2547 GGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDF--DQA 2604
Query: 507 ---CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC 548
C DVDECA R C++ C NT G F C CP GY A G HC
Sbjct: 2605 LGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG-HC 2648
Score = 289 bits (708), Expect = 4e-77
Identities = 242/778 (31%), Positives = 309/778 (39%), Gaps = 109/778 (14%)
Query: 122 GMAQCVNLPGAFECR--CPPGYRLTPSLDECED---VDECGDQRICDHG-DCRN--TIGS 173
G +QCV +P CR C G+ P+L C D CG R C N T
Sbjct: 77 GRSQCV-VP---ICRRACGEGFCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMNGGTCRG 132
Query: 174 YRCECKPGYTLRENVCRDVDECSRPRPVCRNG-------TCENLPGAYLCHCDDGFKAGP 226
C C+ GYT VC C R C NG C + G C+ ++ GP
Sbjct: 133 ASCLCQKGYT--GTVCGQ-PICDRG---CHNGGRCIGPNRCACVYGFMGPQCERDYRTGP 186
Query: 227 NNDCVDVNECREG--GMVCRNGRCRNTVG---SFRCECAP--------GYTLTADGRNCR 273
V C+ G+VC C TVG CE P G+ C+
Sbjct: 187 CFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQ 246
Query: 274 DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPY-VCAGGE 332
DVDEC +P C G SC N G + C C G +L D + V GG
Sbjct: 247 DVDECQAVPGLC--QGG-SCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGR 303
Query: 333 CRNFNGGYV----CECPAG--WRFDKTAAVCV----DERKELCYDEWEAGRCHRAR-PLQ 381
C G+ C C G W +C +E ++LC H P
Sbjct: 304 CAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGL 363
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
L R + +G L Q +D CR ++C+ GR
Sbjct: 364 LGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGR 423
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
C+ T S+RCEC GY G C+D DEC P C +G C N G Y CQC PGF
Sbjct: 424 CLPTPSSYRCECNVGYTQDVRG-ECIDVDECTSSP--CHHGDCVNIPGTYHCQCYPGFQA 480
Query: 502 GPD-QTCVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPR 559
P Q CVDVDEC C RC NT GSF+C C G+ ++ DG +C D +EC
Sbjct: 481 TPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 560 VCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFL 619
C N GS+ C C G+ AP + C DI+EC + +C G C NT+GSF
Sbjct: 541 CVNGVCLNEDGSFSCLCKPGF--LLAP--GGHYCMDIDEC-QTPGICVNGHCTNTEGSFR 595
Query: 620 CDCDAGFEPSEDGTDCIDRRT-GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXG 678
C C G DG C+D TCY ++ G C G
Sbjct: 596 CQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSC--------------------ARPFPG 635
Query: 679 HVTKAQCCC-TLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXX 737
VTK++CCC +G C+LCPA S LC++
Sbjct: 636 TVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSS----------------GLGITTD 679
Query: 738 XXXXLDVFADVDECAAIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ 793
+ D + CA G+C G +RCVC GY +G+ C DVDECA+ CD
Sbjct: 680 GRDINECALDPEVCA--NGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDN 737
Query: 794 -LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
C N+ GSY C C G+ +D C+DVDEC + +C N GSY C C G
Sbjct: 738 GWCQNSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPG 794
Score = 264 bits (646), Expect = 1e-69
Identities = 204/618 (33%), Positives = 259/618 (41%), Gaps = 70/618 (11%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGA-PC-EACPPRGSPAHTALCGEK-------PGEYINP 60
CAG + T+ CCC G W A P E CPPRGS LC ++ PG +
Sbjct: 304 CAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGL 363
Query: 61 VTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+ + + + P P H + G + T+ L + +D C C
Sbjct: 364 LGFGSNGMGP-PLGPARLNP---HGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLC 419
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
+C+ P ++ C C GY EC DVDEC C HGDC N G+Y C+C P
Sbjct: 420 LN-GRCLPTPSSYRCECNVGY-TQDVRGECIDVDECTSSP-CHHGDCVNIPGTYHCQCYP 476
Query: 181 GY--TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECR 237
G+ T C DVDEC +C G C N G++ C C+ GF+ P+ +CVD NEC
Sbjct: 477 GFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECA 536
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTN 297
M C NG C N GSF C C PG+ L G C D+DEC + P C N CTNT
Sbjct: 537 TSTM-CVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDEC-QTPGIC---VNGHCTNTE 591
Query: 298 GGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGEC-RNFNGGYV---CECP-AGWRF 350
G + C C G + GR CVD G C R F G C C F
Sbjct: 592 GSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGF 651
Query: 351 DKTAAVC----VDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPD 406
+ +C E + LC R PE C + R RC
Sbjct: 652 GEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNL 711
Query: 407 SAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
E G G+ D+DEC + +C G C N+ GS+ C CP G+ D C
Sbjct: 712 GYE-----AGASGKD--CTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEIC 764
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDE--C----AEGR-- 517
D DEC P C +G C N G Y C+C PG P T C+D + C E R
Sbjct: 765 KDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE 822
Query: 518 -----ASCTFRCHNTAGSF------RC----TCPYGYAVAADGVHCRDIDECVQEPRVCP 562
AS C T G+ RC C G+A GV C D++EC P VCP
Sbjct: 823 VNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFA-RMTGVTCDDVNECESFPGVCP 881
Query: 563 HA-CENVVGSYICKCPEG 579
+ C N GS+ C+CPEG
Sbjct: 882 NGRCVNTAGSFRCECPEG 899
Score = 257 bits (629), Expect = 1e-67
Identities = 220/687 (32%), Positives = 281/687 (40%), Gaps = 129/687 (18%)
Query: 40 PRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYE 99
P GS A + PG + ID C LC G C TP+ ++C C+ GY
Sbjct: 382 PHGSDAR-GIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYT 440
Query: 100 HDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GD 158
D C DVDEC+ PC CVN+PG + C+C PG++ TP+ C DVDEC
Sbjct: 441 QDVRGE-CIDVDECT--SSPCH-HGDCVNIPGTYHCQCYPGFQATPTRQACVDVDECIVS 496
Query: 159 QRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLC 216
+C G C NT GS++C C G+ L + C D +EC+ +C NG C N G++ C
Sbjct: 497 GGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECA-TSTMCVNGVCLNEDGSFSC 555
Query: 217 HCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV 275
C GF P C+D++EC+ G +C NG C NT GSFRC+C G + DGR C D
Sbjct: 556 LCKPGFLLAPGGHYCMDIDECQTPG-ICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDT 614
Query: 276 ---DEC--------DELPHP---------CGRD----GNPS--CTNTNGG-YECSCGAGW 308
C P P C G P C N ++ C +G
Sbjct: 615 HVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGL 674
Query: 309 KLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCY 366
+ GR D +EC P VCA G C N G Y C C G+ + C D
Sbjct: 675 GITTDGR---DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTD------V 725
Query: 367 DEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM---GRPNL 423
DE C A C G +C+ P S C G +
Sbjct: 726 DE-----C--------ALNSLLCDNG-----WCQNSPGSYSCS----CPPGFHFWQDTEI 763
Query: 424 TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA---------DECAL 474
+D+DEC P CV G C N GS+ C+C G L P G C+D+ E
Sbjct: 764 CKDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRC 821
Query: 475 DPRICG---NGTCSNTRG---GYECQ-------CSPGFTQGPDQTCVDVDECAEGRASC- 520
+ + G C T G G C+ C+ GF + TC DV+EC C
Sbjct: 822 EVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCP 881
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRDI-----------DEC-VQEP-----RVCPH 563
RC NTAGSFRC CP G + A G C D+ DEC V P VC
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCC 941
Query: 564 ACENVVG------------SYICKCPEGYRRTSAP-QDSENACEDINECEEQEDLCSGGV 610
+ V G + CP G S +D+NEC+ LC+ G
Sbjct: 942 SIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT 1001
Query: 611 CINTDGSFLCDCDAGFEPSEDGTDCID 637
C NT GSF C C GF +C D
Sbjct: 1002 CRNTVGSFHCACAGGFALDAQERNCTD 1028
Score = 237 bits (581), Expect = 9e-62
Identities = 170/513 (33%), Positives = 219/513 (42%), Gaps = 93/513 (18%)
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGR 287
N +D+ CR +C NGRC T S+RCEC GYT G C DVDEC P G
Sbjct: 406 NQTIDI--CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDECTSSPCHHG- 461
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECP 345
C N G Y C C G++ R CVD DEC +C G C N G + C C
Sbjct: 462 ----DCVNIPGTYHCQCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCN 517
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
AG+ CVD + C + + C +E ++ C+ P
Sbjct: 518 AGFELSPDGKNCVDHNE-----------CATST---MCVNGVCLNEDGSFSCLCK--PG- 560
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
F+ + GG + D+DEC+ P +CV G C NT+GSFRC+C G + DG
Sbjct: 561 ----FL-LAPGG----HYCMDIDECQT-PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRV 610
Query: 466 CVDA---DEC--ALDPRICGN---GT-------CSNTRGGY--ECQCSPGFTQGPDQTCV 508
CVD C A++ C GT C+N G+ CQ P Q
Sbjct: 611 CVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALC 670
Query: 509 -----------DVDECAEGRASCTFR-CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
D++ECA C C N GS+RC C GY A G C D+DEC
Sbjct: 671 SSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECAL 730
Query: 557 EPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTD 615
+C + C+N GSY C CP G+ QD+E C+D++EC C GVC N
Sbjct: 731 NSLLCDNGWCQNSPGSYSCSCPPGFHFW---QDTE-ICKDVDECLSSP--CVSGVCRNLA 784
Query: 616 GSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXX 675
GS+ C C G GT C+D GTC+ + RCE
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE--------------------VN 824
Query: 676 XXGHVTKAQCCCTLGAAWGSECELCPAPGSPAR 708
G +++CC TLGAAWGS CE C + AR
Sbjct: 825 LQGASLRSECCATLGAAWGSPCERCEIDPACAR 857
Score = 212 bits (517), Expect = 5e-54
Identities = 157/523 (30%), Positives = 203/523 (38%), Gaps = 74/523 (14%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAW---GAPC----------EACPPRGSPAH----TALCGE 52
CA + YLC C G+ GA C + C RG T C
Sbjct: 2177 CAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVC 2236
Query: 53 KPGEYINPVTNETKPID-ECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVD 111
PG P + E D EC P LC G C +T F+C CD G++ T C D+
Sbjct: 2237 PPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIR 2296
Query: 112 E----CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDC 167
+ + CR ++ EC C G P + C +++C HG
Sbjct: 2297 QGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGS- 2355
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN 227
GYT RDVDEC +C +G C N G++ CHC G+
Sbjct: 2356 -------------GYTAEG---RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDAT 2399
Query: 228 -NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C+D++EC + C C+NT GSF C C GY L DGR C+D+DEC H C
Sbjct: 2400 ATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNC- 2457
Query: 287 RDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVC-AGGECRNFNGGYVCECP 345
C NT G + C C G+ + C D DEC P C A G C N G + CEC
Sbjct: 2458 ---QFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECH 2514
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
G+ + C D + C RC QL C C +G +C
Sbjct: 2515 QGFTLVSSGHGCEDVNE--CDGPH---RCQHGCQNQLGGYRCSCPQGFTQHSQWAQCV-- 2567
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
D +EC + P C C NT G FRC CP G+
Sbjct: 2568 --------------------DENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGG 2607
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV 508
C D DECA C +C+NT GG+ C C G+ + CV
Sbjct: 2608 CQDVDECAGRRGPCSY-SCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 180 bits (438), Expect = 2e-44
Identities = 99/242 (40%), Positives = 122/242 (50%), Gaps = 22/242 (9%)
Query: 414 CQGGMGRPNLTQ----DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
CQ G P+ T D+DEC P C C NT GSF C CP GY+L DG +C D
Sbjct: 2390 CQAGY-TPDATATTCLDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDL 2447
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNT 527
DEC C C NT G + C+C PGFTQ Q C D DEC+ C CHNT
Sbjct: 2448 DECTSRQHNC-QFLCVNTVGAFTCRCPPGFTQH-HQACFDNDECSAQPGPCGAHGHCHNT 2505
Query: 528 AGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQ 587
GSFRC C G+ + + G C D++EC P C H C+N +G Y C CP+G+ + S Q
Sbjct: 2506 PGSFRCECHQGFTLVSSGHGCEDVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHS--Q 2562
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE------PSEDGTDCIDRRTG 641
++ C D NEC C C NT G F C C +GF+ +D +C RR G
Sbjct: 2563 WAQ--CVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRR-G 2619
Query: 642 TC 643
C
Sbjct: 2620 PC 2621
Score = 98.7 bits (235), Expect = 8e-20
Identities = 116/418 (27%), Positives = 158/418 (37%), Gaps = 56/418 (13%)
Query: 250 NTVGS-FRCECAPGYTLTADGRNCRDVDECDELPHPCGRD--GNPS-CTNTNGGYECSCG 305
N GS F C PG+ T GR+ V C CG P+ CT +G SCG
Sbjct: 58 NVCGSRFHAYCCPGWR-TFPGRSQCVVPICRRA---CGEGFCSQPNLCTCADGTLAPSCG 113
Query: 306 AG-WKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCE--CPAGWR-FDKTAAVCV--- 358
C++ C+ +C G G +C+ C G R CV
Sbjct: 114 VSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCACVYGF 173
Query: 359 -------DERKELCYDEWEAGRC-HRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
D R C+ + C H+ L + CC + G AWG CE CPA
Sbjct: 174 MGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHP-- 231
Query: 411 MRICQGGMGRPNL----TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
C+ G PN+ QD+DEC+ P +C GG CVN GSF C CP G+ L+ +C
Sbjct: 232 ---CRRGF-IPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAAC 287
Query: 467 VDADECALDPRICGNGTCSNTRGGY----ECQCSPG--FTQGPDQTCVDVDECAEGRASC 520
D A + G G C+ G+ +C C G + GP E + C
Sbjct: 288 EDYRAGACFSVLFG-GRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLC 346
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPE-G 579
R G P G G + + R+ PH GS P G
Sbjct: 347 AQRLPLLPGH-----P-GLFPGLLGFGSNGMGPPLGPARLNPH------GSDARGIPSLG 394
Query: 580 YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
++ + N DI C +LC G C+ T S+ C+C+ G+ G +CID
Sbjct: 395 PGNSNIGTATLNQTIDI--CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRG-ECID 449
Score = 98.3 bits (234), Expect = 1e-19
Identities = 46/113 (40%), Positives = 57/113 (50%), Gaps = 9/113 (7%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL--CHNT 798
D+DEC + C G F C C PG+ + C D DEC+ +P PC CHNT
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNT 2505
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
GS+ C C G+ L G C DV+EC+ H CQ C N G Y CSC G+
Sbjct: 2506 PGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHGCQNQLGGYRCSCPQGF 2557
Score = 97.9 bits (233), Expect = 1e-19
Identities = 51/124 (41%), Positives = 61/124 (49%), Gaps = 11/124 (8%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHN 797
D DECA LC APG +RC C G+ P + C DVDECA C N
Sbjct: 1362 DRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCEN 1421
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRG 855
G + C+C GYELD G NC D++EC + +C NT GSY CSC +E G
Sbjct: 1422 LPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481
Query: 856 DACV 859
CV
Sbjct: 1482 VGCV 1485
Score = 89.0 bits (211), Expect = 6e-17
Identities = 39/103 (37%), Positives = 54/103 (52%), Gaps = 4/103 (3%)
Query: 761 GRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDEDGA 817
G +RC C G+ + C D +ECA+ PP C C NT G + C+C +G++ D+
Sbjct: 2547 GGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALG 2606
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
C+DVDEC C C+NT G + C C GY + G CV
Sbjct: 2607 GCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 84.2 bits (199), Expect = 2e-15
Identities = 49/125 (39%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQ--LC 795
DVDEC P +C G F C C GY R C+DVDEC V CD C
Sbjct: 1238 DVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASC 1297
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEK 853
N GS+ C C G+ DG C D+DEC H C C N GSY C+C G+
Sbjct: 1298 LNIPGSFSCRCLPGWV--GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355
Query: 854 RGDAC 858
G C
Sbjct: 1356 DGFFC 1360
Score = 80.6 bits (190), Expect = 2e-14
Identities = 44/117 (37%), Positives = 53/117 (45%), Gaps = 12/117 (10%)
Query: 747 DVDECAAIPGLCA--------PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCH 796
D DEC+A PG C PG FRC C G+ +G C DV+EC P C C
Sbjct: 2485 DNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHGCQ 2543
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYE 852
N G Y C C G+ A C D +EC TC C NT G + C C G++
Sbjct: 2544 NQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFD 2600
Score = 73.3 bits (172), Expect = 3e-12
Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 7/95 (7%)
Query: 15 GVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIM 74
G+ TK LCC +VG AWG PCE CP + P + G N T + +DEC +
Sbjct: 202 GLVCTKALCCATVGRAWGLPCELCPAQPHPC-------RRGFIPNIHTGACQDVDECQAV 254
Query: 75 PQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
P LC+ G+C + F C C G+ ++S C D
Sbjct: 255 PGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 70.9 bits (166), Expect = 2e-11
Identities = 45/120 (37%), Positives = 58/120 (48%), Gaps = 12/120 (10%)
Query: 751 CAAIPGLCAPGRFRCVCG---PGYRP---AGEVCADVDECAVRPPPC-DQLCHNTDGSYD 803
C A P +P ++ +CG PG+ G+ D+DEC P C + +C N GS+
Sbjct: 1688 CEACPTPISPD-YQILCGNQAPGFLTDIHTGKPL-DIDECGEIPAICANGICINQIGSFR 1745
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE-KRGDACVG 860
C C G+ + C DVDEC CQQ C N GSY C C GY+ G ACVG
Sbjct: 1746 CECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVG 1805
Score = 50.4 bits (115), Expect = 3e-05
Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 32/149 (21%)
Query: 743 DVFADVDECAAIP---GLCA--PGRFRCVCGPGYR--PAGEVCADVDE--C--AVRPPPC 791
++ DVDEC + P G+C G + C CGPG R P+G C D + C ++ C
Sbjct: 762 EICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRC 821
Query: 792 DQLCHNTDGSYDCLCRTGY---------ELDE---------DGANCRDVDECERDTHTCQ 833
+ +C G E+D G C DV+ECE C
Sbjct: 822 EVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCP 881
Query: 834 Q-ICSNTEGSYECSCEDG--YEKRGDACV 859
C NT GS+ C C +G + G CV
Sbjct: 882 NGRCVNTAGSFRCECPEGLMLDASGRLCV 910
Score = 48.0 bits (109), Expect = 1e-04
Identities = 57/195 (29%), Positives = 74/195 (37%), Gaps = 34/195 (17%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
GTC G C C GY T +C C G C +C+ G C C G
Sbjct: 128 GTCR----GASCLCQKGY----TGTVCGQ-PICDRG---CHNGGRCI---GPNRCACVYG 172
Query: 141 YRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRP 200
+ + P +CE D R G C +G C+ + L VC C+
Sbjct: 173 F-MGP---QCER-----DYRT---GPCFGQVGPEGCQ----HQLTGLVCTKALCCATVGR 216
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCEC 259
CE P A C GF + C DV+EC+ +C+ G C N VGSF C C
Sbjct: 217 AW-GLPCELCP-AQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRC 274
Query: 260 APGYTLTADGRNCRD 274
G+ L+ C D
Sbjct: 275 PVGHRLSDSSAACED 289
Score = 38.7 bits (86), Expect = 0.087
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGY 851
CR G+ + C+DVDEC+ CQ C N GS+ C C G+
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGH 278
>AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein.
Length = 2871
Score = 720 bits (1780), Expect = 0.0
Identities = 342/871 (39%), Positives = 468/871 (53%), Gaps = 66/871 (7%)
Query: 6 EDQSCAGAVGVPQTKYLCCCS--VGHAWGAPCEACPPRGSPAHTALCG-EKPGEYINPVT 62
++Q+C G + TK +CCCS +G AW PCE CP + LCG ++PG I+ T
Sbjct: 1702 DNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYT 1761
Query: 63 NETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRG 122
IDEC +P +C+ G C + F+C C G+ +++ +C D+DEC G P C+
Sbjct: 1762 GLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNG-PVCQR 1820
Query: 123 MAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCECKPG 181
A+C+N G++ C C PGYR T S +C D +EC + IC HG C +T+GS+ C C G
Sbjct: 1821 NAECINTAGSYRCDCKPGYRFT-STGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTG 1879
Query: 182 YTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREG 239
+ ++ +C D++EC R C NGTC N G++ C C+ GF NNDC+DV+EC G
Sbjct: 1880 FKTNDDQTMCLDINECERD--ACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASG 1937
Query: 240 -GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
G +CRNG+C NTVGSF+C+C GY + DGR C D++EC P C +C N +G
Sbjct: 1938 NGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPG---TCQNLDG 1994
Query: 299 GYECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV 358
Y C C G+ L +C D DEC E P +CA G C N G + C CP G+ + C
Sbjct: 1995 SYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQ 2054
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCS-EGAAWGRYCERCPAPDSAEFMRICQGG 417
D R CY ++E G+C + ++ ECCC+ +G WG CE CP F +IC G
Sbjct: 2055 DLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYG 2114
Query: 418 ----MGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
+G + D+DEC+ PDVC G+C+NTDGS+RCECP GY+LA G CVD DEC+
Sbjct: 2115 SGIIVGPDDSAVDMDECK-EPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECS 2171
Query: 474 LDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRC 533
+ CGNGTC N GG+EC C GF GP TC D++ECA+ C FRC NT GS+ C
Sbjct: 2172 VG-NPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYEC 2230
Query: 534 TCPYGYAVAADGVHCRDIDECVQEPRVCPH---ACENVVGSYICKCPEGYRRTSAPQDSE 590
CP GY + D C+D DEC + C C+N++G+Y+C C GY+R D E
Sbjct: 2231 KCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRR---PDGE 2287
Query: 591 NACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSG 650
C D NEC+ + +C G C+NT GS+ C+C+ GF S + +C+D R G C+ ++
Sbjct: 2288 -GCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQN 2346
Query: 651 RCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLD 710
C+ VTK++CCC G WG CE+CP G+ A
Sbjct: 2347 MCQ------------------IGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKK 2388
Query: 711 LCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCAPGRFRCVCGPG 770
LC V DV C + G + C+C G
Sbjct: 2389 LCP--------------HGRGFMTNGADIDECKVIHDV--CRNGECVNDRGSYHCICKTG 2432
Query: 771 YRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERD 828
Y P G C D++EC P PC+ +C NT+GSY C C GY L EDG +C+D+DEC
Sbjct: 2433 YTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATK 2492
Query: 829 THTCQQICSNTEGSYECSCEDGYEKRGDACV 859
H CQ +C NT G + C C G+ + +C+
Sbjct: 2493 QHNCQFLCVNTIGGFTCKCPPGFTQHHTSCI 2523
Score = 450 bits (1110), Expect = e-126
Identities = 259/735 (35%), Positives = 348/735 (47%), Gaps = 91/735 (12%)
Query: 161 ICDHGDCRNTIGSYRCECKPGYTLR-ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCD 219
+C +G C T GS RCEC G+ L C DVDEC + P C G C N G+Y C C
Sbjct: 459 LCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEK-NP-CAGGECINNQGSYTCQCR 516
Query: 220 DGFKAG-PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC 278
G+++ +C D++EC + G +C NGRC NT GSF C C G+ +T DG+NC D+DEC
Sbjct: 517 AGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDEC 576
Query: 279 DELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNF 336
+ + C N C N +G ++C C G++L GR C D +EC E P +C G C N
Sbjct: 577 S-IRNMCL---NGMCINEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNGRCVNT 631
Query: 337 NGGYVCECPAGWRFDKTAAVCVDER-KELCYDEWEAGRCHRARPLQLARPECCC-SEGAA 394
+G Y CEC G VCVD + CY ++ G+C + + + ECCC S A
Sbjct: 632 DGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYA 691
Query: 395 WGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECP 454
+G C+ CPA +SAE+ +C G G + D++EC + PD+C G C N G+++C C
Sbjct: 692 FGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICN 751
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDEC 513
GY + G +CVD +EC L+ +C NG C NT G + C C GF PD +TC D+DEC
Sbjct: 752 SGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC 811
Query: 514 AEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE-NVVG-- 570
E C N+ GSF C C + C + + V CE N+ G
Sbjct: 812 -ESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGAT 870
Query: 571 --SYICK------------------CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV 610
S C C +GY R Q CEDI+ECE +C G+
Sbjct: 871 LKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQ-----CEDIDECEVFPGVCKNGL 925
Query: 611 CINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXX 670
C+NT GSF C C +G G C+D R TC+ C
Sbjct: 926 CVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEEC------------------ 967
Query: 671 XXXXXXXGHVTKAQCCCTLGAAWGS-ECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXX 729
G CCC++GAAWG+ ECE CP +P +LC
Sbjct: 968 --TLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCP---------------R 1010
Query: 730 XXXXXXXXXXXXLDVFADVDECAAIPGLCAPGR-------FRCVCGPGYRPAGEV--CAD 780
F D++EC IP LC G+ F+C C G+ E C D
Sbjct: 1011 GPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTD 1070
Query: 781 VDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD-EDGANCRDVDECERDTHTCQ-QICS 837
+DEC + P C + C NT G ++C C GYE NC D+DEC+RD C+ +C
Sbjct: 1071 IDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCH 1130
Query: 838 NTEGSYECSCEDGYE 852
NTEGSY C C G++
Sbjct: 1131 NTEGSYRCECPPGHQ 1145
Score = 442 bits (1090), Expect = e-123
Identities = 292/908 (32%), Positives = 403/908 (44%), Gaps = 138/908 (15%)
Query: 7 DQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETK 66
D C + K CC S+G AWG+PC C + P +CG+ Y + +
Sbjct: 859 DGRCEININGATLKSQCCSSLGAAWGSPCTLC--QVDP----ICGK---GYSRIKGTQCE 909
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDV-----------DECSW 115
IDEC++ P +CK G C +T F+C C G D T +C D+ +EC+
Sbjct: 910 DIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTL 969
Query: 116 ---GR---PPC-------RGMAQCVNLP----GAFECRCP--PGY---RLTPSLDECEDV 153
GR C G +C P +E CP PG+ +T +D+
Sbjct: 970 PIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDI 1029
Query: 154 DECG-DQRICDHGDCRNTIGSYRCECKPGYTL--RENVCRDVDECSRPRPVCRNGTCENL 210
+EC +C HG CRNTIGS++C C G+ L E C D+DEC +C G C N
Sbjct: 1030 NECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 1089
Query: 211 PGAYLCHCDDGFKAG--PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTAD 268
PG + C CD+G+++G +C+D++EC+ ++CR G C NT GS+RCEC PG+ L+ +
Sbjct: 1090 PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPN 1149
Query: 269 GRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPY 326
C D++EC+ H C N C N G Y+C+C G+ R CVD DEC +
Sbjct: 1150 ISACIDINECELSAHLC---PNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNG 1206
Query: 327 VCAGGECRNFNGGYVCECPAGWRF--DKTAAVCVDERKE-------------------LC 365
C C N G Y C C G+ D+ + +DE ++ LC
Sbjct: 1207 GCE-TFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLC 1265
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
YD + A + + EC + CE G G+ T
Sbjct: 1266 YDGFMASEDMKT---CVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCT- 1321
Query: 426 DLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGT 483
D++EC + C C NT GSF+C C G++ DG+ C D DEC+ +C +
Sbjct: 1322 DINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHAD 1379
Query: 484 CSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASC-TFRCHNTAGSFRCTCPYGYAVA 542
C NT G Y C C G+T G TC D+DEC+E C +C N G +RC C G+ +
Sbjct: 1380 CKNTMGSYRCLCKEGYT-GDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPS 1438
Query: 543 ADGVHCRDIDECVQEPRVCPH-ACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEE 601
ADG C DIDEC P +C C N+ G + C+C GY S C D+NEC +
Sbjct: 1439 ADGKACEDIDEC-SLPNICVFGTCHNLPGLFRCECEIGYEL----DRSGGNCTDVNECLD 1493
Query: 602 QEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXX 661
C G C+NT GS++CDC FE + C+D R+G CY + P
Sbjct: 1494 -PTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDI-----RPRGDNGDT 1547
Query: 662 XXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLCT-AVNLTPX 720
V+KA CCC+LG AWG+ CE+CPA + LC P
Sbjct: 1548 ACSNEIGVG---------VSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPN 1598
Query: 721 XXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCAPGR-------FRCVCGPGY-- 771
+ D+DEC +PGLC G+ F+C C GY
Sbjct: 1599 PITV-------------------ILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYL 1639
Query: 772 RPAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDE--CERD 828
VC DV+EC P C C+NT G+Y C+C Y G NC D+ C R+
Sbjct: 1640 NEDTRVCDDVNECET-PGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRN 1698
Query: 829 THTCQQIC 836
+ Q C
Sbjct: 1699 YYADNQTC 1706
Score = 429 bits (1057), Expect = e-119
Identities = 281/835 (33%), Positives = 364/835 (43%), Gaps = 109/835 (13%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P LC+ G CH+T ++C C G++ C D++EC C +CV
Sbjct: 1114 IDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPN-GRCV 1172
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR-- 185
NL G ++C C PGY TP C D+DEC C N+ GSY C C+PG+ L
Sbjct: 1173 NLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPD 1232
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCR 244
+ C D+DEC +C G C N+PG Y C C DGF A + CVDVNEC +C
Sbjct: 1233 QRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICL 1292
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
+G C NT GSF C C GY+ C D++EC+ H CG+ + CTNT G ++CSC
Sbjct: 1293 SGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGK--HAVCTNTAGSFKCSC 1350
Query: 305 GAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
GW G +C D DEC ++C+ +C+N G Y C C G+ D +DE E
Sbjct: 1351 SPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSE 1410
Query: 364 ---LCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGR 420
LC + G+C A C C G P+ D + C
Sbjct: 1411 NLNLCGN----GQCLNAP----GGYRCECDMGFV--------PSADG----KAC------ 1444
Query: 421 PNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG 480
+D+DEC + P++CV G C N G FRCEC GY L G +C D +EC LDP C
Sbjct: 1445 ----EDIDECSL-PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNEC-LDPTTCI 1498
Query: 481 NGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGY 539
+G C NT G Y C C P F P + CVD G R G C+ G
Sbjct: 1499 SGNCVNTPGSYICDCPPDFELNPTRVGCVDT---RSGNCYLDIRPRGDNGDTACSNEIGV 1555
Query: 540 AVAADGVHCRDIDECVQEP-RVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINE 598
V+ C + + P +CP A +C EG+R P EDI+E
Sbjct: 1556 GVSKASC-CCSLGKAWGTPCEMCP-AVNTSEYKILCPGGEGFR----PNPITVILEDIDE 1609
Query: 599 CEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRR---------TGTCYRSL-- 647
C+E LC GG CINT GSF C C G+ +ED C D GTCY ++
Sbjct: 1610 CQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGN 1669
Query: 648 VSGRCEP------------EXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCT--LGAAW 693
+ C P + ++TK CCC+ +G AW
Sbjct: 1670 YTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAW 1729
Query: 694 GSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAA 753
CE CP P + LC L V D+DEC
Sbjct: 1730 NKPCEQCPIPSTDEFATLC---------------GSQRPGFVIDIYTGLPV--DIDECRE 1772
Query: 754 IPGLC-------APGRFRCVCGPG--YRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSY 802
IPG+C G FRC C G Y VC D+DEC P C + C NT GSY
Sbjct: 1773 IPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRNAECINTAGSY 1831
Query: 803 DCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
C C+ GY G C D +EC+ + C C +T GS+ C C G++ D
Sbjct: 1832 RCDCKPGYRFTSTG-QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDD 1885
Score = 423 bits (1041), Expect = e-117
Identities = 214/564 (37%), Positives = 281/564 (49%), Gaps = 26/564 (4%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG-AFECRCPPGY 141
C+ G +C H C E WG PC C P AF CP G
Sbjct: 2061 CYAKFEGGKCSSPKSRNHSKQECCCALKGE-GWG-DPCE---LCPTEPDEAFRQICPYGS 2115
Query: 142 RLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRP 200
+ D+ D+DEC + +C HG C NT GSYRCEC GY L N C D DECS P
Sbjct: 2116 GIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVGNP 2175
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECA 260
C NGTC+N+ G + C C++GF+ GP C D+NEC + ++C RC NT GS+ C+C
Sbjct: 2176 -CGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAF-RCVNTYGSYECKCP 2233
Query: 261 PGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDR 318
GY L D R C+D DEC+E H C + C N G Y C CG G++ G CVD
Sbjct: 2234 VGYVLREDRRMCKDEDECEEGKHDC-TEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDE 2292
Query: 319 DECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCH--R 376
+EC+ P +C G C N G Y CEC G+ C+D R+ C+ E C
Sbjct: 2293 NECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGS 2352
Query: 377 ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDV 436
+ + + ECCC G WG +CE CP + F ++C G G D+DEC+V DV
Sbjct: 2353 SNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDV 2412
Query: 437 CVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCS 496
C G CVN GS+ C C GY G SCVD +EC P+ C N C NT G Y+C C
Sbjct: 2413 CRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPC-NFICKNTEGSYQCSCP 2471
Query: 497 PGF-TQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECV 555
G+ Q ++C D+DECA + +C F C NT G F C CP G+ C D +EC
Sbjct: 2472 KGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGF--TQHHTSCIDNNECT 2529
Query: 556 QEPRVC--PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCIN 613
+ +C C+N GS+ C+C G+ + + ++CED++ECE C G C N
Sbjct: 2530 SDINLCGSKGICQNTPGSFTCECQRGF----SLDQTGSSCEDVDECEGNH-RCQHG-CQN 2583
Query: 614 TDGSFLCDCDAGFEPSEDGTDCID 637
G + C C G+ C+D
Sbjct: 2584 IIGGYRCSCPQGYLQHYQWNQCVD 2607
Score = 422 bits (1040), Expect = e-117
Identities = 224/589 (38%), Positives = 291/589 (49%), Gaps = 48/589 (8%)
Query: 6 EDQSCAGAVGVPQTKYLCCCSVGHAWGAP-CEACPPRGSPAHTALCGEKPGEYINPVTNE 64
ED+ C + CCCSVG AWG CE CP R +P + LC PG +TN
Sbjct: 963 EDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNG 1022
Query: 65 T---KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
K I+EC ++P LC G C +T F+C CD G+ D+ C D+DEC C
Sbjct: 1023 KPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLC- 1081
Query: 122 GMAQCVNLPGAFECRCPPGYRL-TPSLDECEDVDEC-GDQRICDHGDCRNTIGSYRCECK 179
G QCVN PG FEC+C GY + C D+DEC D +C G C NT GSYRCEC
Sbjct: 1082 GRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECP 1141
Query: 180 PGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNEC 236
PG+ L N+ C D++EC +C NG C NL G Y C C+ G+ + P+ CVD++EC
Sbjct: 1142 PGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDEC 1201
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
C C N+ GS+ C C PG+ L D R+C D+DEC++ P+ C DG CTN
Sbjct: 1202 SIMNGGCET-FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNIC--DGG-QCTNI 1257
Query: 297 NGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTA 354
G Y C C G+ + CVD +EC P +C G C N G ++C C G+ K
Sbjct: 1258 PGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGK 1317
Query: 355 AVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC 414
C D +E E G H + C + ++ C
Sbjct: 1318 TGCTD------INECEIG-AHNC-----GKHAVCTNTAGSFKCSCS-------------- 1351
Query: 415 QGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
G +G DLDEC +C C NT GS+RC C +GY DG +C D DEC+
Sbjct: 1352 PGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY--TGDGFTCTDLDECS 1409
Query: 474 LDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFR 532
+ +CGNG C N GGY C+C GF D + C D+DEC+ CHN G FR
Sbjct: 1410 ENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFR 1469
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
C C GY + G +C D++EC+ +P C C N GSYIC CP +
Sbjct: 1470 CECEIGYELDRSGGNCTDVNECL-DPTTCISGNCVNTPGSYICDCPPDF 1517
Score = 390 bits (959), Expect = e-107
Identities = 234/680 (34%), Positives = 330/680 (48%), Gaps = 97/680 (14%)
Query: 19 TKYLCCC-SVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQL 77
TK CCC S +A+G PC+ CP + S + ALC PG +T+ I+EC + P +
Sbjct: 679 TKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPG-----MTSAGSDINECALDPDI 733
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRC 137
C G C + ++C C+ GYE D+T C D++EC C QC N PG+F C C
Sbjct: 734 CPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDN-GQCRNTPGSFVCTC 792
Query: 138 PPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL--RENVCRD---- 191
P G+ P L CED+DEC + C +G C+N+ GS+ CEC TL + +C +
Sbjct: 793 PKGFIYKPDLKTCEDIDEC-ESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKG 851
Query: 192 ------VD---ECSRPRPVCRNGTCENLPGAY-----LCH----CDDGFKAGPNNDCVDV 233
+D E + ++ C +L A+ LC C G+ C D+
Sbjct: 852 TCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDI 911
Query: 234 NECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV--DEC------DELPHP- 284
+EC VC+NG C NT GSF+C+C G TL A GR C D+ + C +E P
Sbjct: 912 DECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPI 971
Query: 285 CGRDGNPSCTNTNGG-----------------YE--CSCGAGW---KLVGRRCVDRD--E 320
GR +C + G YE C G G+ ++ + +D E
Sbjct: 972 AGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINE 1031
Query: 321 CKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKELCYDEWEAGRCHRARP 379
CK +P +C G+CRN G + C C +G+ D C D + + D G+C P
Sbjct: 1032 CKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT-P 1090
Query: 380 LQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG 439
EC C EG G M+ C D+DEC+ P +C G
Sbjct: 1091 GDF---ECKCDEGYESG-----------FMMMKNC----------MDIDECQRDPLLCRG 1126
Query: 440 GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGF 499
G C NT+GS+RCECP G+ L+P+ +C+D +EC L +C NG C N G Y+C C+PG+
Sbjct: 1127 GVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGY 1186
Query: 500 TQGPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEP 558
PD+ CVD+DEC+ C C N+ GS+ C+C G+A+ D C DIDEC P
Sbjct: 1187 HSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNP 1246
Query: 559 RVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGS 617
+C C N+ G Y C C +G+ A +D + C D+NEC+ ++C G C NT GS
Sbjct: 1247 NICDGGQCTNIPGEYRCLCYDGF---MASEDMK-TCVDVNECDLNPNICLSGTCENTKGS 1302
Query: 618 FLCDCDAGFEPSEDGTDCID 637
F+C CD G+ + T C D
Sbjct: 1303 FICHCDMGYSGKKGKTGCTD 1322
Score = 365 bits (899), Expect = e-100
Identities = 236/659 (35%), Positives = 309/659 (46%), Gaps = 84/659 (12%)
Query: 6 EDQSCAGAVGVPQTKYLCCCSV-GHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNE 64
E C+ +K CCC++ G WG PCE CP A +C G + P +
Sbjct: 2066 EGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGP-DDS 2124
Query: 65 TKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+DEC P +CK G C +T ++C C GY C D DECS G P C G
Sbjct: 2125 AVDMDECK-EPDVCKHGQCINTDGSYRCECPFGYILAGNE--CVDTDECSVGNP-C-GNG 2179
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
C N+ G FEC C G+ P + CED++EC + C NT GSY C+C GY L
Sbjct: 2180 TCKNVIGGFECTCEEGFEPGPMMT-CEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVL 2238
Query: 185 REN--VCRDVDECSRPRPVC--RNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREG 239
RE+ +C+D DEC + C + C+NL G Y+C C G++ P+ + CVD NEC+
Sbjct: 2239 REDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTK 2298
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE--C--DELPHPCGRDGNPSCTN 295
+C NGRC NT GS+ CEC G+T + + C D E C + L + C +
Sbjct: 2299 PGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPV 2358
Query: 296 TNGGYECSCGAGW----------------KLV--GRRCV----DRDECKELPYVCAGGEC 333
T C G GW KL GR + D DECK + VC GEC
Sbjct: 2359 TKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGEC 2418
Query: 334 RNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRA-RPLQLARPECCCSEG 392
N G Y C C G+ D T CVD C++A +P C +EG
Sbjct: 2419 VNDRGSYHCICKTGYTPDITGTSCVD-----------LNECNQAPKPCNFI---CKNTEG 2464
Query: 393 AAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCE 452
+ +C P I Q GR +DLDEC + C CVNT G F C+
Sbjct: 2465 SY------QCSCPKGY----ILQED-GRS--CKDLDECATKQHNCQF-LCVNTIGGFTCK 2510
Query: 453 CPDGYVLAPDGLSCVDADECALDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQT---CV 508
CP G+ SC+D +EC D +CG+ G C NT G + C+C GF+ DQT C
Sbjct: 2511 CPPGFT--QHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSL--DQTGSSCE 2566
Query: 509 DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CEN 567
DVDEC EG C C N G +RC+CP GY C D +EC+ +C A C N
Sbjct: 2567 DVDEC-EGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECL-SAHICGGASCHN 2624
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
+GSY C CP G++ + C+DINEC + CS G NT+G +LC C G+
Sbjct: 2625 TLGSYKCMCPAGFQY----EQFSGGCQDINECGSAQAPCSYG-SSNTEGGYLCGCPPGY 2678
Score = 360 bits (885), Expect = 1e-98
Identities = 216/651 (33%), Positives = 304/651 (46%), Gaps = 71/651 (10%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C KPG + K I+EC+ P +C G C +T ++C C G +C D
Sbjct: 596 CICKPGFQLASDGRYCKDINECET-PGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVD 654
Query: 110 V---DECSWG--RPPC---------RGMAQCVNLPGAFECRCPP-------GYRLT---- 144
C G R C + C + AF C P Y+
Sbjct: 655 THMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG 714
Query: 145 PSLDEC-EDVDECG-DQRICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRP 200
P + D++EC D IC +G C N G+Y+C C GY + C D++EC
Sbjct: 715 PGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSL 774
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCRNGRCRNTVGSFRCEC 259
+C NG C N PG+++C C GF P+ C D++EC C NG C+N+ GSF CEC
Sbjct: 775 LCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSP--CINGVCKNSPGSFICEC 832
Query: 260 APGYTLTADGRNCRDVDE--CDE--LPHPC-----GRDGNPSCTNTNG---GYECS---- 303
+ TL C + + C + + C G C ++ G G C+
Sbjct: 833 SSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQV 892
Query: 304 ---CGAGW-KLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD 359
CG G+ ++ G +C D DEC+ P VC G C N G + C+CP+G D T +C+D
Sbjct: 893 DPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLD 952
Query: 360 ERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWG-RYCERCPAPDSAEFMRICQGGM 418
R E C+ +E C + CCCS GAAWG CE CP ++ E+ +C G
Sbjct: 953 IRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGP 1012
Query: 419 G--RPNLT------QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDAD 470
G +T +D++EC++ P +C G+C NT GSF+C C G+ L + +C D D
Sbjct: 1013 GFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDID 1072
Query: 471 ECALDPRICGNGTCSNTRGGYECQCSPGFTQG--PDQTCVDVDECAEGRASCTFR-CHNT 527
EC + P +CG G C NT G +EC+C G+ G + C+D+DEC C CHNT
Sbjct: 1073 ECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNT 1132
Query: 528 AGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAP 586
GS+RC CP G+ ++ + C DI+EC +CP+ C N++G Y C C GY T
Sbjct: 1133 EGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHST--- 1189
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+EC C C N++GS+ C C GF D C D
Sbjct: 1190 -PDRLFCVDIDECSIMNGGCE-TFCTNSEGSYECSCQPGFALMPDQRSCTD 1238
Score = 348 bits (856), Expect = 4e-95
Identities = 236/691 (34%), Positives = 310/691 (44%), Gaps = 100/691 (14%)
Query: 24 CCSVGHAWGAPC---EACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKP 80
C V PC E +GS +T C + G E + IDEC ++C
Sbjct: 488 CIDVDECEKNPCAGGECINNQGS--YTCQC--RAGYQSTLTRTECRDIDECLQNGRICNN 543
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
G C +T F C C+ G+ C D+DECS GM C+N G+F+C C PG
Sbjct: 544 GRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGM--CINEDGSFKCICKPG 601
Query: 141 YRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYT--LRENVCRDV------ 192
++L C+D++EC IC +G C NT GSYRCEC PG L VC D
Sbjct: 602 FQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTC 661
Query: 193 ------DECSRP-------RPVCRNGT-------CENLP----GAYLCHCDDGFKAGPNN 228
+C +P C T C+ P Y C G G +
Sbjct: 662 YGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG--PGMTS 719
Query: 229 DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRD 288
D+NEC +C NG C N G+++C C GY + + G+NC D++EC C
Sbjct: 720 AGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLC--- 776
Query: 289 GNPSCTNTNGGYECSCGAG--WKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPA 346
N C NT G + C+C G +K + C D DEC+ P C G C+N G ++CEC +
Sbjct: 777 DNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSP--CINGVCKNSPGSFICECSS 834
Query: 347 GWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPD 406
D T +C++ K C+ GRC + +CC S GAAWG C C
Sbjct: 835 ESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDP 894
Query: 407 SAEFMRICQGGMGRPNLTQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
IC G R TQ D+DEC V P VC G CVNT GSF+C+CP G L G
Sbjct: 895 ------ICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGR 948
Query: 465 SCVDA-----------DECAL--------DPRICGNGTCSNTRGGYECQ----------C 495
C+D +EC L D C G T EC C
Sbjct: 949 ICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELC 1008
Query: 496 --SPGF-----TQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYAVAADGVH 547
PGF T G D++EC + CT +C NT GSF+C C G+A+ ++ +
Sbjct: 1009 PRGPGFATKEITNG-KPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERN 1067
Query: 548 CRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLC 606
C DIDEC P +C C N G + CKC EGY S +N C DI+EC+ LC
Sbjct: 1068 CTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYE--SGFMMMKN-CMDIDECQRDPLLC 1124
Query: 607 SGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
GGVC NT+GS+ C+C G + S + + CID
Sbjct: 1125 RGGVCHNTEGSYRCECPPGHQLSPNISACID 1155
Score = 342 bits (841), Expect = 3e-93
Identities = 217/683 (31%), Positives = 311/683 (45%), Gaps = 82/683 (12%)
Query: 7 DQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETK 66
D +C+ +GV +K CCCS+G AWG PCE CP + + LC G NP+T +
Sbjct: 1546 DTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILE 1605
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
IDEC +P LC+ G C +T FQC C GY + + +C DV+EC P G C
Sbjct: 1606 DIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECE--TPGICGPGTC 1663
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDE--C-----GDQRICDHGDCRNTIGSYRCECK 179
N G + C CPP Y + C D+ C D + CD G+ + C C
Sbjct: 1664 YNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCD-GELLFNMTKKMCCC- 1721
Query: 180 PGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREG 239
Y + + ++C P C + ++ G VD++ECRE
Sbjct: 1722 -SYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLP-------VDIDECREI 1773
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGG 299
VC NG C N VGSFRCEC G+ C D+DEC P C R N C NT G
Sbjct: 1774 PGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGP-VCQR--NAECINTAGS 1830
Query: 300 YECSCGAGWKLVGR-RCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV 358
Y C C G++ +C DR+EC+E+P +C+ G+C + G + C C G++ + +C+
Sbjct: 1831 YRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCL 1890
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
D E D G C + C C+ G F+ +
Sbjct: 1891 D-INECERDACGNGTCRNT----IGSFNCRCNHG-----------------FI------L 1922
Query: 419 GRPNLTQDLDECRV-RPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPR 477
N D+DEC ++C G+C+NT GSF+C+C +GY +APDG +CVD +EC L+PR
Sbjct: 1923 SHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPR 1982
Query: 478 ICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRCTCP 536
C GTC N G Y C C PG++ ++ C D+DEC E C C NT GSF+C CP
Sbjct: 1983 KCAPGTCQNLDGSYRCICPPGYSL-QNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCP 2041
Query: 537 YGYAVAADGVHCRDI--DECVQ--EPRVCPHACENVVGSYICKCP---EGYRRTS--APQ 587
G+++++ G C+D+ C E C C C EG+ P
Sbjct: 2042 EGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPT 2101
Query: 588 DSENACEDI------------NECEEQEDLCSGGVC-----INTDGSFLCDCDAGFEPSE 630
+ + A I + + ++ VC INTDGS+ C+C G+ +
Sbjct: 2102 EPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILA- 2160
Query: 631 DGTDCIDRRTGTCYRSLVSGRCE 653
G +C+D + +G C+
Sbjct: 2161 -GNECVDTDECSVGNPCGNGTCK 2182
Score = 318 bits (780), Expect = 7e-86
Identities = 189/546 (34%), Positives = 252/546 (46%), Gaps = 41/546 (7%)
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCR 168
D+DEC P QC+N G++ C CP GY L + EC D DEC C +G C+
Sbjct: 2127 DMDECK--EPDVCKHGQCINTDGSYRCECPFGYILAGN--ECVDTDECSVGNPCGNGTCK 2182
Query: 169 NTIGSYRCECKPGYTLRENV-CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN 227
N IG + C C+ G+ + C D++EC++ +C C N G+Y C C G+ +
Sbjct: 2183 NVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAF-RCVNTYGSYECKCPVGYVLRED 2241
Query: 228 ND-CVDVNECREGGMVC--RNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHP 284
C D +EC EG C + C+N +G++ C C PGY DG C D +EC P
Sbjct: 2242 RRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGI 2301
Query: 285 CGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDE--C--KELPYVCA-GGECRNFN 337
C N C NT G Y C C G+ + C+D E C + L +C G RN
Sbjct: 2302 CE---NGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPV 2358
Query: 338 GGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGR 397
C C G + +C + GR + EC
Sbjct: 2359 TKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADI--DECKVIHDVCRNG 2416
Query: 398 YCERCPAPDSAEFMRICQGGMGRPNLTQ----DLDECRVRPDVCVGGRCVNTDGSFRCEC 453
C D + IC+ G P++T DL+EC P C C NT+GS++C C
Sbjct: 2417 ECVN----DRGSYHCICKTGY-TPDITGTSCVDLNECNQAPKPC-NFICKNTEGSYQCSC 2470
Query: 454 PDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDEC 513
P GY+L DG SC D DECA C C NT GG+ C+C PGFTQ +C+D +EC
Sbjct: 2471 PKGYILQEDGRSCKDLDECATKQHNC-QFLCVNTIGGFTCKCPPGFTQH-HTSCIDNNEC 2528
Query: 514 AEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGS 571
C + C NT GSF C C G+++ G C D+DEC R C H C+N++G
Sbjct: 2529 TSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHR-CQHGCQNIIGG 2587
Query: 572 YICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSED 631
Y C CP+GY + N C D NEC +C G C NT GS+ C C AGF+ +
Sbjct: 2588 YRCSCPQGYLQ----HYQWNQCVDENECLSAH-ICGGASCHNTLGSYKCMCPAGFQYEQF 2642
Query: 632 GTDCID 637
C D
Sbjct: 2643 SGGCQD 2648
Score = 313 bits (769), Expect = 2e-84
Identities = 232/764 (30%), Positives = 307/764 (40%), Gaps = 82/764 (10%)
Query: 135 CRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYT---LRENVCRD 191
C CP G ++ PS + C + R + G C + C C+ GY + VC
Sbjct: 100 CTCPSG-QIAPSCGS-RSIQHC-NIRCMNGGSCSDD----HCLCQKGYIGTHCGQPVCES 152
Query: 192 VDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE--GGMVCRNGRCR 249
C C G C+ ++ GP + C+ G+VC C
Sbjct: 153 --GCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCC 210
Query: 250 NTVG---SFRCECAP--------GYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
TVG CE P G+ C+DVDEC +P C + GN C NT G
Sbjct: 211 ATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLC-QGGN--CINTVG 267
Query: 299 GYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
+EC C AG KL V ++C D DEC +P +C GGEC N Y C+CP G+
Sbjct: 268 SFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTR 327
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYC----ERCPAPDSAEFMR 412
C+D R CY GRC P + + +CCC G W E CP + +F +
Sbjct: 328 CIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNK 387
Query: 413 ICQGGM---GRPN-----LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
+C M GRP L V P G + P P L
Sbjct: 388 LCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSRE--PPRVL 445
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
D C L +C NG C T G C+C+ GF C+DVDEC E C
Sbjct: 446 PVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDEC-EKNPCAGGEC 504
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRT 583
N GS+ C C GY CRDIDEC+Q R+C + C N GS+ C C G+ T
Sbjct: 505 INNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVT 564
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRR---- 639
+D +N CED++EC + ++C G+CIN DGSF C C GF+ + DG C D
Sbjct: 565 ---RDGKN-CEDMDECSIR-NMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECET 619
Query: 640 -----TGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTL-GAAW 693
G C + S RCE G + QC L GA
Sbjct: 620 PGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVT 679
Query: 694 GSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAA 753
SEC C A A + C P +D++ECA
Sbjct: 680 KSEC--CCASTEYAFGEPCQP---CPAQNSAEYQALCSSGPGMTSAG-----SDINECAL 729
Query: 754 IPGLC-------APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ-LCHNTDGSYD 803
P +C G ++C+C GY G+ C D++EC + CD C NT GS+
Sbjct: 730 DPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFV 789
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSC 847
C C G+ D C D+DECE + +C N+ GS+ C C
Sbjct: 790 CTCPKGFIYKPDLKTCEDIDECE-SSPCINGVCKNSPGSFICEC 832
Score = 289 bits (709), Expect = 3e-77
Identities = 193/556 (34%), Positives = 252/556 (45%), Gaps = 73/556 (13%)
Query: 63 NETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRG 122
NE DEC + C GTC + GF+C C+ G+E C D++EC+ + P
Sbjct: 2162 NECVDTDECSV-GNPCGNGTCKNVIGGFECTCEEGFE-PGPMMTCEDINECA--QNPLLC 2217
Query: 123 MAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHG--DCRNTIGSYRCECK 179
+CVN G++EC+CP GY L C+D DEC + + C +C+N IG+Y C C
Sbjct: 2218 AFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICG 2277
Query: 180 PGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNE- 235
PGY R + C D +EC +C NG C N G+Y C C+DGF A PN D C+D E
Sbjct: 2278 PGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREG 2337
Query: 236 -CREGGM--VCRNGRC-RNTVGSFRCECAPGY------------------TLTADGR--- 270
C + +C+ G RN V C C G L GR
Sbjct: 2338 YCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFM 2397
Query: 271 -NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK--LVGRRCVDRDECKELPYV 327
N D+DEC + C R+G C N G Y C C G+ + G CVD +EC + P
Sbjct: 2398 TNGADIDECKVIHDVC-RNGE--CVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKP 2454
Query: 328 CAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPEC 387
C C+N G Y C CP G+ + C D DE A + H + L C
Sbjct: 2455 C-NFICKNTEGSYQCSCPKGYILQEDGRSCKD------LDEC-ATKQHNCQFL------C 2500
Query: 388 CCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDG 447
+ G G C +CP P + C + T D++ C + G C NT G
Sbjct: 2501 VNTIG---GFTC-KCP-PGFTQHHTSC---IDNNECTSDINLCGSK------GICQNTPG 2546
Query: 448 SFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QT 506
SF CEC G+ L G SC D DEC + R C +G C N GGY C C G+ Q
Sbjct: 2547 SFTCECQRGFSLDQTGSSCEDVDECEGNHR-CQHG-CQNIIGGYRCSCPQGYLQHYQWNQ 2604
Query: 507 CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
CVD +EC CHNT GS++C CP G+ C+DI+EC C +
Sbjct: 2605 CVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGSS 2664
Query: 567 NVVGSYICKCPEGYRR 582
N G Y+C CP GY R
Sbjct: 2665 NTEGGYLCGCPPGYFR 2680
Score = 239 bits (585), Expect = 3e-62
Identities = 180/563 (31%), Positives = 246/563 (43%), Gaps = 65/563 (11%)
Query: 34 PCEACPPRGSPAHTALCGEKPGEYINPVTNETK--PI---DECDIMPQLCKPGTCHDTPT 88
P PP P P EY+ P + P+ D C ++ LC+ G C TP
Sbjct: 411 PVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPG 470
Query: 89 GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD 148
+C C+ G++ D C DVDEC + PC G +C+N G++ C+C GY+ T +
Sbjct: 471 SCRCECNKGFQLDLRGE-CIDVDECE--KNPCAG-GECINNQGSYTCQCRAGYQSTLTRT 526
Query: 149 ECEDVDEC-GDQRICDHGDCRNTIGSYRCECKPGY--TLRENVCRDVDECSRPRPVCRNG 205
EC D+DEC + RIC++G C NT GS+ C C G+ T C D+DECS R +C NG
Sbjct: 527 ECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECS-IRNMCLNG 585
Query: 206 TCENLPGAYLCHCDDGFK-AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYT 264
C N G++ C C GF+ A C D+NEC G +C NGRC NT GS+RCEC PG
Sbjct: 586 MCINEDGSFKCICKPGFQLASDGRYCKDINECETPG-ICMNGRCVNTDGSYRCECFPGLA 644
Query: 265 LTADGRNCRDVDECDELPHPC-GRDGNPSCTNTNGG----YECSCGAGWKLVGRRC--VD 317
+ DGR C D + C G C G EC C + G C
Sbjct: 645 VGLDGRVCVDT----HMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCP 700
Query: 318 RDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER---KELCYDEWEAGRC 374
E +C+ G G + EC +C + R K +C +E
Sbjct: 701 AQNSAEYQALCSSGPGMTSAGSDINECALDPDICPN-GICENLRGTYKCICNSGYEVDST 759
Query: 375 HRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC-QGGMGRPNL--TQDLDECR 431
+ + EC + C P F+ C +G + +P+L +D+DEC
Sbjct: 760 GKN---CVDINECVLNSLLCDNGQCRNTP----GSFVCTCPKGFIYKPDLKTCEDIDECE 812
Query: 432 VRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDAD-----ECALDPR--ICGNGT- 483
P C+ G C N+ GSF CEC L P C++ + +D R I NG
Sbjct: 813 SSP--CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGAT 870
Query: 484 ----CSNTRG---GYECQ-------CSPGFTQGPDQTCVDVDECAEGRASC-TFRCHNTA 528
C ++ G G C C G+++ C D+DEC C C NT
Sbjct: 871 LKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTR 930
Query: 529 GSFRCTCPYGYAVAADGVHCRDI 551
GSF+C CP G + A G C DI
Sbjct: 931 GSFKCQCPSGMTLDATGRICLDI 953
Score = 230 bits (563), Expect = 1e-59
Identities = 153/483 (31%), Positives = 211/483 (43%), Gaps = 46/483 (9%)
Query: 193 DECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTV 252
D C R +C+NG C PG+ C C+ GF+ +C+DV+EC + C G C N
Sbjct: 451 DYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKN--PCAGGECINNQ 508
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV- 311
GS+ C+C GY T CRD+DEC + C N C NT+G + C C AG+ +
Sbjct: 509 GSYTCQCRAGYQSTLTRTECRDIDECLQNGRIC---NNGRCINTDGSFHCVCNAGFHVTR 565
Query: 312 -GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWE 370
G+ C D DEC + +C G C N +G + C C G++ C D +E E
Sbjct: 566 DGKNCEDMDEC-SIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKD------INECE 618
Query: 371 A-GRCHRARPLQL-ARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLD 428
G C R + C C G A G C C GG R + L
Sbjct: 619 TPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCV---DTHMRSTCYGGYKRGQCIKPLF 675
Query: 429 ECRVRPDVCVGGRCVNTDGSF--RCE-CP-----DGYVLAPDGLSCV----DADECALDP 476
+ + C C +T+ +F C+ CP + L G D +ECALDP
Sbjct: 676 GAVTKSECC----CASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDP 731
Query: 477 RICGNGTCSNTRGGYECQCSPGF-TQGPDQTCVDVDECAEGRASC-TFRCHNTAGSFRCT 534
IC NG C N RG Y+C C+ G+ + CVD++EC C +C NT GSF CT
Sbjct: 732 DICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCT 791
Query: 535 CPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACE 594
CP G+ D C DIDEC P + C+N GS+IC+C S ++ C
Sbjct: 792 CPKGFIYKPDLKTCEDIDECESSPCI-NGVCKNSPGSFICECSS----ESTLDPTKTICI 846
Query: 595 DINECEEQEDLCSGGVCINTDGSFL---CDCDAGFEPSEDGTDC-IDRRTGTCYRSLVSG 650
+ + + + G IN +G+ L C G T C +D G Y +
Sbjct: 847 ETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGT 906
Query: 651 RCE 653
+CE
Sbjct: 907 QCE 909
Score = 213 bits (520), Expect = 2e-54
Identities = 148/478 (30%), Positives = 198/478 (41%), Gaps = 71/478 (14%)
Query: 66 KPIDECDIMPQLC--KPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGM 123
K DEC+ C K C + + C C GY+ C D +EC C
Sbjct: 2246 KDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICEN- 2304
Query: 124 AQCVNLPGAFECRCPPGYRLTPSLDECEDVDE--CGD---QRICDHGDC-RNTIGSYRCE 177
+C+N G++ C C G+ +P+ DEC D E C Q +C G RN + C
Sbjct: 2305 GRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECC 2364
Query: 178 CK--------------PGYTLRENVC----------RDVDECSRPRPVCRNGTCENLPGA 213
C G + +C D+DEC VCRNG C N G+
Sbjct: 2365 CDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGS 2424
Query: 214 YLCHCDDGFKAG-PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNC 272
Y C C G+ CVD+NEC + C N C+NT GS++C C GY L DGR+C
Sbjct: 2425 YHCICKTGYTPDITGTSCVDLNECNQAPKPC-NFICKNTEGSYQCSCPKGYILQEDGRSC 2483
Query: 273 RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAG-G 331
+D+DEC H C C NT GG+ C C G+ C+D +EC +C G
Sbjct: 2484 KDLDECATKQHNC----QFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKG 2539
Query: 332 ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAG-RCHRARPLQLARPECCCS 390
C+N G + CEC G+ D+T + C D DE E RC + C C
Sbjct: 2540 ICQNTPGSFTCECQRGFSLDQTGSSCED------VDECEGNHRCQHGCQNIIGGYRCSCP 2593
Query: 391 EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFR 450
+G +C D +EC + +C G C NT GS++
Sbjct: 2594 QGYLQHYQWNQCV----------------------DENEC-LSAHICGGASCHNTLGSYK 2630
Query: 451 CECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV 508
C CP G+ C D +EC C G+ SNT GGY C C PG+ + CV
Sbjct: 2631 CMCPAGFQYEQFSGGCQDINECGSAQAPCSYGS-SNTEGGYLCGCPPGYFRIGQGHCV 2687
Score = 140 bits (339), Expect = 2e-32
Identities = 113/358 (31%), Positives = 146/358 (40%), Gaps = 39/358 (10%)
Query: 210 LPGAYLCH-CDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGS-FRCECAPGYTLTA 267
L +Y H D +AG + R GG + N GS + C PG+
Sbjct: 16 LLASYTSHGADANLEAGNVKETRASRAKRRGGGGHDALKGPNVCGSRYNAYCCPGWKTLP 75
Query: 268 DGRNCRDVDECDELPHPCGRDG---NPS-CTNTNGGYECSCGA-GWKLVGRRCVDRDECK 322
G C V C H CG DG P+ CT +G SCG+ + RC++ C
Sbjct: 76 GGNQCI-VPICR---HSCG-DGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCS 130
Query: 323 ELPYVCAGGECRNFNGGYVCE--CPAGWRF--DKTAAVCVDERKELCYDEWEAGRCHRAR 378
+ +C G G VCE C G R A C ++ G C
Sbjct: 131 DDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVI 190
Query: 379 PLQLARPE----------CCCSEGAAWGRYCERCPAPDSAEFMRICQGGMG---RPNLTQ 425
Q+ + + CC + G AWG CE CPA C+ G R Q
Sbjct: 191 SNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHP-----CRRGFIPNIRTGACQ 245
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
D+DEC+ P +C GG C+NT GSF C+CP G+ L C D DEC+ P IC G C+
Sbjct: 246 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECT 305
Query: 486 NTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFRCHN----TAGSFRCTCPYG 538
NT Y C+C PGF PD T C+DV A RC N + +C C G
Sbjct: 306 NTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 363
Score = 128 bits (308), Expect = 1e-28
Identities = 99/330 (30%), Positives = 132/330 (40%), Gaps = 53/330 (16%)
Query: 411 MRICQGGMGRPNL-TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
M C G P+ ++ + C +R C+ G + D C C GY+ G ++
Sbjct: 99 MCTCPSGQIAPSCGSRSIQHCNIR---CMNGGSCSDD---HCLCQKGYIGTHCGQPVCES 152
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS---CTFR-CH 525
C R C+ T G QC + GP T + C +G+ S CT C
Sbjct: 153 G-CLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMC-QGQLSGIVCTKTLCC 210
Query: 526 NTAG---SFRCT--------CPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYI 573
T G C C G+ C+D+DEC P +C C N VGS+
Sbjct: 211 ATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFE 270
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGT 633
CKCP G++ Q CEDI+EC +C GG C NT S+ C C GF S DGT
Sbjct: 271 CKCPAGHKLNEVSQK----CEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGT 326
Query: 634 DCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAW 693
CID R G CY +L +GRC + +TK QCCC G W
Sbjct: 327 RCIDVRPGYCYTALTNGRCSNQLPQS--------------------ITKMQCCCDAGRCW 366
Query: 694 GSEC----ELCPAPGSPARLDLCTAVNLTP 719
E+CP + LC+ + P
Sbjct: 367 SPGVTVAPEMCPIRATEDFNKLCSVPMVIP 396
Score = 123 bits (297), Expect = 2e-27
Identities = 76/245 (31%), Positives = 102/245 (41%), Gaps = 19/245 (7%)
Query: 2 EWNEEDQSCAGAVGVPQTKYLCCCSVGHAW---GAPCEACPPRGSPAHTA--LCGEKPGE 56
E N+ + C + Y C C G+ G C+ + H LC G
Sbjct: 2447 ECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGG 2506
Query: 57 YINP-----VTNETKPID--ECDIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLCR 108
+ + T ID EC LC G C +TP F C C G+ D T C
Sbjct: 2507 FTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE 2566
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCR 168
DVDEC G C+ C N+ G + C CP GY ++C D +EC IC C
Sbjct: 2567 DVDECE-GNHRCQH--GCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCH 2623
Query: 169 NTIGSYRCECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGP 226
NT+GSY+C C G+ + C+D++EC + C G+ N G YLC C G+
Sbjct: 2624 NTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGS-SNTEGGYLCGCPPGYFRIG 2682
Query: 227 NNDCV 231
CV
Sbjct: 2683 QGHCV 2687
Score = 120 bits (289), Expect = 2e-26
Identities = 66/194 (34%), Positives = 93/194 (47%), Gaps = 19/194 (9%)
Query: 7 DQSCAGAV-GVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNET 65
+Q C G + G+ TK LCC +VG AWG PCE CP + P + G N T
Sbjct: 192 NQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPC-------RRGFIPNIRTGAC 244
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ 125
+ +DEC +P LC+ G C +T F+C C G++ + S C D+DECS C G +
Sbjct: 245 QDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEG-GE 303
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRN----TIGSYRCEC--- 178
C N ++ C+CPPG+ +P C DV +G C N +I +C C
Sbjct: 304 CTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 363
Query: 179 ---KPGYTLRENVC 189
PG T+ +C
Sbjct: 364 RCWSPGVTVAPEMC 377
Score = 97.5 bits (232), Expect = 2e-19
Identities = 46/124 (37%), Positives = 65/124 (52%), Gaps = 12/124 (9%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYRPAGEV--CADVDECAVRPPPC-DQLCH 796
D+DEC P +C PG +RC+C G+ + ++ C DV+EC + P C C
Sbjct: 1238 DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCE 1297
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKR 854
NT GS+ C C GY + C D++ECE H C +C+NT GS++CSC G+
Sbjct: 1298 NTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGD 1357
Query: 855 GDAC 858
G C
Sbjct: 1358 GIKC 1361
Score = 97.1 bits (231), Expect = 2e-19
Identities = 48/122 (39%), Positives = 61/122 (50%), Gaps = 12/122 (9%)
Query: 747 DVDECAAIPGLCA-------PGRFRCVCGPGYRPAGEV---CADVDECAVRPPPC-DQLC 795
D+DEC P LC PG F C C GY + C D+DEC P C +C
Sbjct: 1070 DIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVC 1129
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKR 854
HNT+GSY C C G++L + + C D++ECE H C C N G Y+C+C GY
Sbjct: 1130 HNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHST 1189
Query: 855 GD 856
D
Sbjct: 1190 PD 1191
Score = 96.3 bits (229), Expect = 4e-19
Identities = 47/113 (41%), Positives = 57/113 (50%), Gaps = 9/113 (7%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNT 798
D+DECA C G F C C PG+ C D +EC C +C NT
Sbjct: 2485 DLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNT 2544
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
GS+ C C+ G+ LD+ G++C DVDECE H CQ C N G Y CSC GY
Sbjct: 2545 PGSFTCECQRGFSLDQTGSSCEDVDECE-GNHRCQHGCQNIIGGYRCSCPQGY 2596
Score = 94.3 bits (224), Expect = 2e-18
Identities = 45/115 (39%), Positives = 58/115 (50%), Gaps = 10/115 (8%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ-LCH 796
D+DEC P LC G +RC C PG++ P C D++EC + C C
Sbjct: 1113 DIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCV 1172
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
N G Y C C GY D C D+DEC C+ C+N+EGSYECSC+ G+
Sbjct: 1173 NLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGF 1227
Score = 91.5 bits (217), Expect = 1e-17
Identities = 44/118 (37%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 747 DVDECAAIP---GLCA--PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQ-LCHNT 798
DVDEC P G C G + C C GY+ C D+DEC C+ C NT
Sbjct: 490 DVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINT 549
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
DGS+ C+C G+ + DG NC D+DEC +C N +GS++C C+ G++ D
Sbjct: 550 DGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASD 607
Score = 90.2 bits (214), Expect = 3e-17
Identities = 49/125 (39%), Positives = 62/125 (49%), Gaps = 15/125 (12%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYR-PAGEV-CADVDECAVRPPPCDQ--LC 795
DV+EC P +C G F C C GY G+ C D++EC + C + +C
Sbjct: 1280 DVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVC 1339
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEK 853
NT GS+ C C G+ DG C D+DEC TH C Q C NT GSY C C++GY
Sbjct: 1340 TNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTG 1397
Query: 854 RGDAC 858
G C
Sbjct: 1398 DGFTC 1402
Score = 85.8 bits (203), Expect = 6e-16
Identities = 38/94 (40%), Positives = 55/94 (58%), Gaps = 5/94 (5%)
Query: 765 CVCGPGYRPAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
C GPG AG +D++ECA+ P C +C N G+Y C+C +GYE+D G NC D++
Sbjct: 711 CSSGPGMTSAG---SDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDIN 767
Query: 824 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
EC ++ C C NT GS+ C+C G+ + D
Sbjct: 768 ECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPD 801
Score = 82.2 bits (194), Expect = 7e-15
Identities = 41/100 (41%), Positives = 51/100 (51%), Gaps = 5/100 (5%)
Query: 760 PGRFRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG RC C G++ GE C DVDEC P + C N GSY C CR GY+
Sbjct: 469 PGSCRCECNKGFQLDLRGE-CIDVDECEKNPCAGGE-CINNQGSYTCQCRAGYQSTLTRT 526
Query: 818 NCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
CRD+DEC ++ C C NT+GS+ C C G+ D
Sbjct: 527 ECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRD 566
Score = 79.0 bits (186), Expect = 7e-14
Identities = 38/102 (37%), Positives = 50/102 (49%), Gaps = 3/102 (2%)
Query: 761 GRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
G +RC C GY + C D +EC CHNT GSY C+C G++ ++
Sbjct: 2586 GGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGG 2645
Query: 819 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
C+D++EC C SNTEG Y C C GY + G CV
Sbjct: 2646 CQDINECGSAQAPCSYGSSNTEGGYLCGCPPGYFRIGQGHCV 2687
Score = 71.7 bits (168), Expect = 1e-11
Identities = 41/112 (36%), Positives = 51/112 (45%), Gaps = 8/112 (7%)
Query: 746 ADVDECAAIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTDGS 801
+D++ C + G+C PG F C C G+ G C DVDEC C C N G
Sbjct: 2530 SDINLCGS-KGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHR-CQHGCQNIIGG 2587
Query: 802 YDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYE 852
Y C C GY C D +EC H C C NT GSY+C C G++
Sbjct: 2588 YRCSCPQGYLQHYQWNQCVDENEC-LSAHICGGASCHNTLGSYKCMCPAGFQ 2638
Score = 70.1 bits (164), Expect = 3e-11
Identities = 32/76 (42%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Query: 778 CADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ-QI 835
C DVDEC P C C NT GS++C C G++L+E C D+DEC C+
Sbjct: 244 CQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGE 303
Query: 836 CSNTEGSYECSCEDGY 851
C+NT SY C C G+
Sbjct: 304 CTNTVSSYFCKCPPGF 319
Score = 69.7 bits (163), Expect = 4e-11
Identities = 43/118 (36%), Positives = 53/118 (44%), Gaps = 14/118 (11%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ-LCH 796
DVDEC AIPGLC G F C C G++ + C D+DEC+ P C+ C
Sbjct: 246 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECT 305
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSN----TEGSYECSCEDG 850
NT SY C C G+ DG C DV T CSN + +C C+ G
Sbjct: 306 NTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 363
Score = 50.4 bits (115), Expect = 3e-05
Identities = 38/155 (24%), Positives = 52/155 (33%), Gaps = 12/155 (7%)
Query: 560 VCPHACENVVGSY--ICKCPEGYRRTSAPQDSENACE----DINECEEQEDLCSGGVCIN 613
+C H+C + S +C CP G S S C + C + LC G
Sbjct: 84 ICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGT 143
Query: 614 TDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXX 673
G +C+ +G C+ C +CE +
Sbjct: 144 HCGQPVCESGC-----LNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQ 198
Query: 674 XXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPAR 708
TK CC T+G AWG CE+CPA P R
Sbjct: 199 LSGIV-CTKTLCCATVGRAWGHPCEMCPAQPHPCR 232
Score = 43.6 bits (98), Expect = 0.003
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE 852
CR G+ + C+DVDEC+ CQ C NT GS+EC C G++
Sbjct: 231 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHK 278
Score = 39.1 bits (87), Expect = 0.066
Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 3/73 (4%)
Query: 790 PCDQLCHNTDGSYDCLCR--TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECS 846
PC+ Y LC G+ + D+DEC+ CQ C NT GS++C
Sbjct: 1573 PCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCR 1632
Query: 847 CEDGYEKRGDACV 859
C GY D V
Sbjct: 1633 CPTGYYLNEDTRV 1645
>X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein.
Length = 3002
Score = 719 bits (1777), Expect = 0.0
Identities = 342/871 (39%), Positives = 467/871 (53%), Gaps = 66/871 (7%)
Query: 6 EDQSCAGAVGVPQTKYLCCCS--VGHAWGAPCEACPPRGSPAHTALCG-EKPGEYINPVT 62
++Q+C G + TK +CCCS +G AW PCE CP + LCG ++PG I+ T
Sbjct: 1833 DNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYT 1892
Query: 63 NETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRG 122
IDEC +P +C+ G C + F+C C G+ +++ +C D+DEC G P C+
Sbjct: 1893 GLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNG-PVCQR 1951
Query: 123 MAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCECKPG 181
A+C+N G++ C C PGYR T S +C D +EC + IC HG C +T+GS+ C C G
Sbjct: 1952 NAECINTAGSYRCDCKPGYRFT-STGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTG 2010
Query: 182 YTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREG 239
+ ++ +C D++EC R C NGTC N G++ C C+ GF NNDC+DV+EC G
Sbjct: 2011 FKTNDDQTMCLDINECERD--ACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASG 2068
Query: 240 -GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
G +CRNG+C NTVGSF+C+C GY + DGR C D++EC P C +C N +G
Sbjct: 2069 NGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPG---TCQNLDG 2125
Query: 299 GYECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV 358
Y C C G+ L +C D DEC E P +CA G C N G + C CP G+ + C
Sbjct: 2126 SYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQ 2185
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCS-EGAAWGRYCERCPAPDSAEFMRICQGG 417
D R CY ++E G+C + ++ ECCC+ +G WG CE CP F +IC G
Sbjct: 2186 DLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYG 2245
Query: 418 ----MGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
+G + D+DEC+ PDVC G+C+NTDGS+RCECP GY LA G CVD DEC+
Sbjct: 2246 SGIIVGPDDSAVDMDECK-EPDVCKHGQCINTDGSYRCECPFGYTLA--GNECVDTDECS 2302
Query: 474 LDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRC 533
+ CGNGTC N GG+EC C GF GP TC D++ECA+ C FRC NT GS+ C
Sbjct: 2303 VG-NPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYEC 2361
Query: 534 TCPYGYAVAADGVHCRDIDECVQEPRVCPH---ACENVVGSYICKCPEGYRRTSAPQDSE 590
CP GY + D C+D DEC + C C+N++G+Y+C C GY+R D E
Sbjct: 2362 KCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRR---PDGE 2418
Query: 591 NACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSG 650
C D NEC+ + +C G C+NT GS+ C+C+ GF S + +C+D R G C+ ++
Sbjct: 2419 -GCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQN 2477
Query: 651 RCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLD 710
C+ VTK++CCC G WG CE+CP G+ A
Sbjct: 2478 MCQ------------------IGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKK 2519
Query: 711 LCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCAPGRFRCVCGPG 770
LC V DV C + G + C+C G
Sbjct: 2520 LCP--------------HGRGFMTNGADIDECKVIHDV--CRNGECVNDRGSYHCICKTG 2563
Query: 771 YRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERD 828
Y P G C D++EC P PC+ +C NT+GSY C C GY L EDG +C+D+DEC
Sbjct: 2564 YTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATK 2623
Query: 829 THTCQQICSNTEGSYECSCEDGYEKRGDACV 859
H CQ +C NT G + C C G+ + +C+
Sbjct: 2624 QHNCQFLCVNTIGGFTCKCPPGFTQHHTSCI 2654
Score = 454 bits (1119), Expect = e-127
Identities = 260/735 (35%), Positives = 349/735 (47%), Gaps = 91/735 (12%)
Query: 161 ICDHGDCRNTIGSYRCECKPGYTLR-ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCD 219
+C +G C T GSYRCEC G+ L C DVDEC + P C G C N G+Y C C
Sbjct: 590 LCQNGRCIPTPGSYRCECNKGFQLDLRGECIDVDECEK-NP-CAGGECINNQGSYTCQCR 647
Query: 220 DGFKAG-PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC 278
G+++ +C D++EC + G +C NGRC NT GSF C C G+ +T DG+NC D+DEC
Sbjct: 648 AGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDEC 707
Query: 279 DELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNF 336
+ + C N C N +G ++C C G++L GR C D +EC E P +C G C N
Sbjct: 708 S-IRNMCL---NGMCINEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNGRCVNT 762
Query: 337 NGGYVCECPAGWRFDKTAAVCVDER-KELCYDEWEAGRCHRARPLQLARPECCC-SEGAA 394
+G Y CEC G VCVD + CY ++ G+C + + + ECCC S A
Sbjct: 763 DGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYA 822
Query: 395 WGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECP 454
+G C+ CPA +SAE+ +C G G + D++EC + PD+C G C N G+++C C
Sbjct: 823 FGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICN 882
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDEC 513
GY + G +CVD +EC L+ +C NG C NT G + C C GF PD +TC D+DEC
Sbjct: 883 SGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC 942
Query: 514 AEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE-NVVG-- 570
E C N+ GSF C C + C + + V CE N+ G
Sbjct: 943 -ESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGAT 1001
Query: 571 --SYICK------------------CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV 610
S C C +GY R Q CEDI+ECE +C G+
Sbjct: 1002 LKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQ-----CEDIDECEVFPGVCKNGL 1056
Query: 611 CINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXX 670
C+NT GSF C C +G G C+D R TC+ C
Sbjct: 1057 CVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEEC------------------ 1098
Query: 671 XXXXXXXGHVTKAQCCCTLGAAWGS-ECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXX 729
G CCC++GAAWG+ ECE CP +P +LC
Sbjct: 1099 --TLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCP---------------R 1141
Query: 730 XXXXXXXXXXXXLDVFADVDECAAIPGLCAPGR-------FRCVCGPGYRPAGEV--CAD 780
F D++EC IP LC G+ F+C C G+ E C D
Sbjct: 1142 GPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTD 1201
Query: 781 VDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD-EDGANCRDVDECERDTHTCQ-QICS 837
+DEC + P C + C NT G ++C C GYE NC D+DEC+RD C+ +C
Sbjct: 1202 IDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCH 1261
Query: 838 NTEGSYECSCEDGYE 852
NTEGSY C C G++
Sbjct: 1262 NTEGSYRCECPPGHQ 1276
Score = 442 bits (1090), Expect = e-123
Identities = 292/908 (32%), Positives = 403/908 (44%), Gaps = 138/908 (15%)
Query: 7 DQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETK 66
D C + K CC S+G AWG+PC C + P +CG+ Y + +
Sbjct: 990 DGRCEININGATLKSQCCSSLGAAWGSPCTLC--QVDP----ICGK---GYSRIKGTQCE 1040
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDV-----------DECSW 115
IDEC++ P +CK G C +T F+C C G D T +C D+ +EC+
Sbjct: 1041 DIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTL 1100
Query: 116 ---GR---PPC-------RGMAQCVNLP----GAFECRCP--PGY---RLTPSLDECEDV 153
GR C G +C P +E CP PG+ +T +D+
Sbjct: 1101 PIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDI 1160
Query: 154 DECG-DQRICDHGDCRNTIGSYRCECKPGYTL--RENVCRDVDECSRPRPVCRNGTCENL 210
+EC +C HG CRNTIGS++C C G+ L E C D+DEC +C G C N
Sbjct: 1161 NECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 1220
Query: 211 PGAYLCHCDDGFKAG--PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTAD 268
PG + C CD+G+++G +C+D++EC+ ++CR G C NT GS+RCEC PG+ L+ +
Sbjct: 1221 PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPN 1280
Query: 269 GRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPY 326
C D++EC+ H C N C N G Y+C+C G+ R CVD DEC +
Sbjct: 1281 ISACIDINECELSAHLC---PNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNG 1337
Query: 327 VCAGGECRNFNGGYVCECPAGWRF--DKTAAVCVDERKE-------------------LC 365
C C N G Y C C G+ D+ + +DE ++ LC
Sbjct: 1338 GCE-TFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLC 1396
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
YD + A + + EC + CE G G+ T
Sbjct: 1397 YDGFMASEDMKT---CVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCT- 1452
Query: 426 DLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGT 483
D++EC + C C NT GSF+C C G++ DG+ C D DEC+ +C +
Sbjct: 1453 DINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHAD 1510
Query: 484 CSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASC-TFRCHNTAGSFRCTCPYGYAVA 542
C NT G Y C C G+T G TC D+DEC+E C +C N G +RC C G+ +
Sbjct: 1511 CKNTMGSYRCLCKEGYT-GDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPS 1569
Query: 543 ADGVHCRDIDECVQEPRVCPH-ACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEE 601
ADG C DIDEC P +C C N+ G + C+C GY S C D+NEC +
Sbjct: 1570 ADGKACEDIDEC-SLPNICVFGTCHNLPGLFRCECEIGYEL----DRSGGNCTDVNECLD 1624
Query: 602 QEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXX 661
C G C+NT GS++CDC FE + C+D R+G CY + P
Sbjct: 1625 -PTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDI-----RPRGDNGDT 1678
Query: 662 XXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLCT-AVNLTPX 720
V+KA CCC+LG AWG+ CE+CPA + LC P
Sbjct: 1679 ACSNEIGVG---------VSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPN 1729
Query: 721 XXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCAPGR-------FRCVCGPGY-- 771
+ D+DEC +PGLC G+ F+C C GY
Sbjct: 1730 PITV-------------------ILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYL 1770
Query: 772 RPAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDE--CERD 828
VC DV+EC P C C+NT G+Y C+C Y G NC D+ C R+
Sbjct: 1771 NEDTRVCDDVNECET-PGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRN 1829
Query: 829 THTCQQIC 836
+ Q C
Sbjct: 1830 YYADNQTC 1837
Score = 429 bits (1057), Expect = e-119
Identities = 281/835 (33%), Positives = 364/835 (43%), Gaps = 109/835 (13%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P LC+ G CH+T ++C C G++ C D++EC C +CV
Sbjct: 1245 IDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPN-GRCV 1303
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR-- 185
NL G ++C C PGY TP C D+DEC C N+ GSY C C+PG+ L
Sbjct: 1304 NLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPD 1363
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCR 244
+ C D+DEC +C G C N+PG Y C C DGF A + CVDVNEC +C
Sbjct: 1364 QRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICL 1423
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
+G C NT GSF C C GY+ C D++EC+ H CG+ + CTNT G ++CSC
Sbjct: 1424 SGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGK--HAVCTNTAGSFKCSC 1481
Query: 305 GAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
GW G +C D DEC ++C+ +C+N G Y C C G+ D +DE E
Sbjct: 1482 SPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSE 1541
Query: 364 ---LCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGR 420
LC + G+C A C C G P+ D + C
Sbjct: 1542 NLNLCGN----GQCLNAP----GGYRCECDMGFV--------PSADG----KAC------ 1575
Query: 421 PNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG 480
+D+DEC + P++CV G C N G FRCEC GY L G +C D +EC LDP C
Sbjct: 1576 ----EDIDECSL-PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNEC-LDPTTCI 1629
Query: 481 NGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGY 539
+G C NT G Y C C P F P + CVD G R G C+ G
Sbjct: 1630 SGNCVNTPGSYICDCPPDFELNPTRVGCVDT---RSGNCYLDIRPRGDNGDTACSNEIGV 1686
Query: 540 AVAADGVHCRDIDECVQEP-RVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINE 598
V+ C + + P +CP A +C EG+R P EDI+E
Sbjct: 1687 GVSKASC-CCSLGKAWGTPCEMCP-AVNTSEYKILCPGGEGFR----PNPITVILEDIDE 1740
Query: 599 CEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRR---------TGTCYRSL-- 647
C+E LC GG CINT GSF C C G+ +ED C D GTCY ++
Sbjct: 1741 CQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGN 1800
Query: 648 VSGRCEP------------EXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCT--LGAAW 693
+ C P + ++TK CCC+ +G AW
Sbjct: 1801 YTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAW 1860
Query: 694 GSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAA 753
CE CP P + LC L V D+DEC
Sbjct: 1861 NKPCEQCPIPSTDEFATLC---------------GSQRPGFVIDIYTGLPV--DIDECRE 1903
Query: 754 IPGLC-------APGRFRCVCGPG--YRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSY 802
IPG+C G FRC C G Y VC D+DEC P C + C NT GSY
Sbjct: 1904 IPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRNAECINTAGSY 1962
Query: 803 DCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
C C+ GY G C D +EC+ + C C +T GS+ C C G++ D
Sbjct: 1963 RCDCKPGYRFTSTG-QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDD 2016
Score = 425 bits (1047), Expect = e-118
Identities = 215/564 (38%), Positives = 282/564 (50%), Gaps = 26/564 (4%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG-AFECRCPPGY 141
C+ G +C H C E WG PC C P AF CP G
Sbjct: 2192 CYAKFEGGKCSSPKSRNHSKQECCCALKGE-GWG-DPCE---LCPTEPDEAFRQICPYGS 2246
Query: 142 RLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRP 200
+ D+ D+DEC + +C HG C NT GSYRCEC GYTL N C D DECS P
Sbjct: 2247 GIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYTLAGNECVDTDECSVGNP 2306
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECA 260
C NGTC+N+ G + C C++GF+ GP C D+NEC + ++C RC NT GS+ C+C
Sbjct: 2307 -CGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAF-RCVNTYGSYECKCP 2364
Query: 261 PGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDR 318
GY L D R C+D DEC+E H C + C N G Y C CG G++ G CVD
Sbjct: 2365 VGYVLREDRRMCKDEDECEEGKHDC-TEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDE 2423
Query: 319 DECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCH--R 376
+EC+ P +C G C N G Y CEC G+ C+D R+ C+ E C
Sbjct: 2424 NECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGS 2483
Query: 377 ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDV 436
+ + + ECCC G WG +CE CP + F ++C G G D+DEC+V DV
Sbjct: 2484 SNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDV 2543
Query: 437 CVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCS 496
C G CVN GS+ C C GY G SCVD +EC P+ C N C NT G Y+C C
Sbjct: 2544 CRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPC-NFICKNTEGSYQCSCP 2602
Query: 497 PGF-TQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECV 555
G+ Q ++C D+DECA + +C F C NT G F C CP G+ C D +EC
Sbjct: 2603 KGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGF--TQHHTSCIDNNECT 2660
Query: 556 QEPRVC--PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCIN 613
+ +C C+N GS+ C+C G+ + + ++CED++ECE C G C N
Sbjct: 2661 SDINLCGSKGICQNTPGSFTCECQRGF----SLDQTGSSCEDVDECEGNH-RCQHG-CQN 2714
Query: 614 TDGSFLCDCDAGFEPSEDGTDCID 637
G + C C G+ C+D
Sbjct: 2715 IIGGYRCSCPQGYLQHYQWNQCVD 2738
Score = 422 bits (1040), Expect = e-117
Identities = 224/589 (38%), Positives = 291/589 (49%), Gaps = 48/589 (8%)
Query: 6 EDQSCAGAVGVPQTKYLCCCSVGHAWGAP-CEACPPRGSPAHTALCGEKPGEYINPVTNE 64
ED+ C + CCCSVG AWG CE CP R +P + LC PG +TN
Sbjct: 1094 EDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNG 1153
Query: 65 T---KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
K I+EC ++P LC G C +T F+C CD G+ D+ C D+DEC C
Sbjct: 1154 KPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLC- 1212
Query: 122 GMAQCVNLPGAFECRCPPGYRL-TPSLDECEDVDEC-GDQRICDHGDCRNTIGSYRCECK 179
G QCVN PG FEC+C GY + C D+DEC D +C G C NT GSYRCEC
Sbjct: 1213 GRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECP 1272
Query: 180 PGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNEC 236
PG+ L N+ C D++EC +C NG C NL G Y C C+ G+ + P+ CVD++EC
Sbjct: 1273 PGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDEC 1332
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
C C N+ GS+ C C PG+ L D R+C D+DEC++ P+ C DG CTN
Sbjct: 1333 SIMNGGCET-FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNIC--DGG-QCTNI 1388
Query: 297 NGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTA 354
G Y C C G+ + CVD +EC P +C G C N G ++C C G+ K
Sbjct: 1389 PGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGK 1448
Query: 355 AVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC 414
C D +E E G H + C + ++ C
Sbjct: 1449 TGCTD------INECEIG-AHNC-----GKHAVCTNTAGSFKCSCS-------------- 1482
Query: 415 QGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
G +G DLDEC +C C NT GS+RC C +GY DG +C D DEC+
Sbjct: 1483 PGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY--TGDGFTCTDLDECS 1540
Query: 474 LDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFR 532
+ +CGNG C N GGY C+C GF D + C D+DEC+ CHN G FR
Sbjct: 1541 ENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFR 1600
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
C C GY + G +C D++EC+ +P C C N GSYIC CP +
Sbjct: 1601 CECEIGYELDRSGGNCTDVNECL-DPTTCISGNCVNTPGSYICDCPPDF 1648
Score = 390 bits (959), Expect = e-107
Identities = 234/680 (34%), Positives = 330/680 (48%), Gaps = 97/680 (14%)
Query: 19 TKYLCCC-SVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQL 77
TK CCC S +A+G PC+ CP + S + ALC PG +T+ I+EC + P +
Sbjct: 810 TKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPG-----MTSAGSDINECALDPDI 864
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRC 137
C G C + ++C C+ GYE D+T C D++EC C QC N PG+F C C
Sbjct: 865 CPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDN-GQCRNTPGSFVCTC 923
Query: 138 PPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL--RENVCRD---- 191
P G+ P L CED+DEC + C +G C+N+ GS+ CEC TL + +C +
Sbjct: 924 PKGFIYKPDLKTCEDIDEC-ESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKG 982
Query: 192 ------VD---ECSRPRPVCRNGTCENLPGAY-----LCH----CDDGFKAGPNNDCVDV 233
+D E + ++ C +L A+ LC C G+ C D+
Sbjct: 983 TCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDI 1042
Query: 234 NECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV--DEC------DELPHP- 284
+EC VC+NG C NT GSF+C+C G TL A GR C D+ + C +E P
Sbjct: 1043 DECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPI 1102
Query: 285 CGRDGNPSCTNTNGG-----------------YE--CSCGAGW---KLVGRRCVDRD--E 320
GR +C + G YE C G G+ ++ + +D E
Sbjct: 1103 AGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINE 1162
Query: 321 CKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKELCYDEWEAGRCHRARP 379
CK +P +C G+CRN G + C C +G+ D C D + + D G+C P
Sbjct: 1163 CKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT-P 1221
Query: 380 LQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG 439
EC C EG G M+ C D+DEC+ P +C G
Sbjct: 1222 GDF---ECKCDEGYESG-----------FMMMKNC----------MDIDECQRDPLLCRG 1257
Query: 440 GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGF 499
G C NT+GS+RCECP G+ L+P+ +C+D +EC L +C NG C N G Y+C C+PG+
Sbjct: 1258 GVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGY 1317
Query: 500 TQGPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEP 558
PD+ CVD+DEC+ C C N+ GS+ C+C G+A+ D C DIDEC P
Sbjct: 1318 HSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNP 1377
Query: 559 RVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGS 617
+C C N+ G Y C C +G+ A +D + C D+NEC+ ++C G C NT GS
Sbjct: 1378 NICDGGQCTNIPGEYRCLCYDGF---MASEDMK-TCVDVNECDLNPNICLSGTCENTKGS 1433
Query: 618 FLCDCDAGFEPSEDGTDCID 637
F+C CD G+ + T C D
Sbjct: 1434 FICHCDMGYSGKKGKTGCTD 1453
Score = 370 bits (911), Expect = e-102
Identities = 237/659 (35%), Positives = 310/659 (47%), Gaps = 84/659 (12%)
Query: 6 EDQSCAGAVGVPQTKYLCCCSV-GHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNE 64
E C+ +K CCC++ G WG PCE CP A +C G + P +
Sbjct: 2197 EGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGP-DDS 2255
Query: 65 TKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+DEC P +CK G C +T ++C C GY C D DECS G P C G
Sbjct: 2256 AVDMDECK-EPDVCKHGQCINTDGSYRCECPFGYTLAGNE--CVDTDECSVGNP-C-GNG 2310
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
C N+ G FEC C G+ P + CED++EC + C NT GSY C+C GY L
Sbjct: 2311 TCKNVIGGFECTCEEGFEPGPMMT-CEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVL 2369
Query: 185 REN--VCRDVDECSRPRPVC--RNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREG 239
RE+ +C+D DEC + C + C+NL G Y+C C G++ P+ + CVD NEC+
Sbjct: 2370 REDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTK 2429
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE--C--DELPHPCGRDGNPSCTN 295
+C NGRC NT GS+ CEC G+T + + C D E C + L + C +
Sbjct: 2430 PGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPV 2489
Query: 296 TNGGYECSCGAGW----------------KLV--GRRCV----DRDECKELPYVCAGGEC 333
T C G GW KL GR + D DECK + VC GEC
Sbjct: 2490 TKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGEC 2549
Query: 334 RNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRA-RPLQLARPECCCSEG 392
N G Y C C G+ D T CVD C++A +P C +EG
Sbjct: 2550 VNDRGSYHCICKTGYTPDITGTSCVD-----------LNECNQAPKPCNFI---CKNTEG 2595
Query: 393 AAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCE 452
+ +C P I Q GR +DLDEC + C CVNT G F C+
Sbjct: 2596 SY------QCSCPKGY----ILQED-GRS--CKDLDECATKQHNCQF-LCVNTIGGFTCK 2641
Query: 453 CPDGYVLAPDGLSCVDADECALDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQT---CV 508
CP G+ SC+D +EC D +CG+ G C NT G + C+C GF+ DQT C
Sbjct: 2642 CPPGFT--QHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSL--DQTGSSCE 2697
Query: 509 DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CEN 567
DVDEC EG C C N G +RC+CP GY C D +EC+ +C A C N
Sbjct: 2698 DVDEC-EGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECL-SAHICGGASCHN 2755
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
+GSY C CP G++ + C+DINEC + CS G C NT+G +LC C G+
Sbjct: 2756 TLGSYKCMCPAGFQY----EQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGCPPGY 2809
Score = 360 bits (885), Expect = 1e-98
Identities = 216/651 (33%), Positives = 304/651 (46%), Gaps = 71/651 (10%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C KPG + K I+EC+ P +C G C +T ++C C G +C D
Sbjct: 727 CICKPGFQLASDGRYCKDINECET-PGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVD 785
Query: 110 V---DECSWG--RPPC---------RGMAQCVNLPGAFECRCPP-------GYRLT---- 144
C G R C + C + AF C P Y+
Sbjct: 786 THMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG 845
Query: 145 PSLDEC-EDVDECG-DQRICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRP 200
P + D++EC D IC +G C N G+Y+C C GY + C D++EC
Sbjct: 846 PGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSL 905
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCRNGRCRNTVGSFRCEC 259
+C NG C N PG+++C C GF P+ C D++EC C NG C+N+ GSF CEC
Sbjct: 906 LCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSP--CINGVCKNSPGSFICEC 963
Query: 260 APGYTLTADGRNCRDVDE--CDE--LPHPC-----GRDGNPSCTNTNG---GYECS---- 303
+ TL C + + C + + C G C ++ G G C+
Sbjct: 964 SSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQV 1023
Query: 304 ---CGAGW-KLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD 359
CG G+ ++ G +C D DEC+ P VC G C N G + C+CP+G D T +C+D
Sbjct: 1024 DPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLD 1083
Query: 360 ERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWG-RYCERCPAPDSAEFMRICQGGM 418
R E C+ +E C + CCCS GAAWG CE CP ++ E+ +C G
Sbjct: 1084 IRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGP 1143
Query: 419 G--RPNLT------QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDAD 470
G +T +D++EC++ P +C G+C NT GSF+C C G+ L + +C D D
Sbjct: 1144 GFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDID 1203
Query: 471 ECALDPRICGNGTCSNTRGGYECQCSPGFTQG--PDQTCVDVDECAEGRASCTFR-CHNT 527
EC + P +CG G C NT G +EC+C G+ G + C+D+DEC C CHNT
Sbjct: 1204 ECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNT 1263
Query: 528 AGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAP 586
GS+RC CP G+ ++ + C DI+EC +CP+ C N++G Y C C GY T
Sbjct: 1264 EGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHST--- 1320
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+EC C C N++GS+ C C GF D C D
Sbjct: 1321 -PDRLFCVDIDECSIMNGGCE-TFCTNSEGSYECSCQPGFALMPDQRSCTD 1369
Score = 348 bits (856), Expect = 4e-95
Identities = 236/691 (34%), Positives = 310/691 (44%), Gaps = 100/691 (14%)
Query: 24 CCSVGHAWGAPC---EACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKP 80
C V PC E +GS +T C + G E + IDEC ++C
Sbjct: 619 CIDVDECEKNPCAGGECINNQGS--YTCQC--RAGYQSTLTRTECRDIDECLQNGRICNN 674
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
G C +T F C C+ G+ C D+DECS GM C+N G+F+C C PG
Sbjct: 675 GRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGM--CINEDGSFKCICKPG 732
Query: 141 YRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYT--LRENVCRDV------ 192
++L C+D++EC IC +G C NT GSYRCEC PG L VC D
Sbjct: 733 FQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTC 792
Query: 193 ------DECSRP-------RPVCRNGT-------CENLP----GAYLCHCDDGFKAGPNN 228
+C +P C T C+ P Y C G G +
Sbjct: 793 YGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG--PGMTS 850
Query: 229 DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRD 288
D+NEC +C NG C N G+++C C GY + + G+NC D++EC C
Sbjct: 851 AGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLC--- 907
Query: 289 GNPSCTNTNGGYECSCGAG--WKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPA 346
N C NT G + C+C G +K + C D DEC+ P C G C+N G ++CEC +
Sbjct: 908 DNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSP--CINGVCKNSPGSFICECSS 965
Query: 347 GWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPD 406
D T +C++ K C+ GRC + +CC S GAAWG C C
Sbjct: 966 ESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDP 1025
Query: 407 SAEFMRICQGGMGRPNLTQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
IC G R TQ D+DEC V P VC G CVNT GSF+C+CP G L G
Sbjct: 1026 ------ICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGR 1079
Query: 465 SCVDA-----------DECAL--------DPRICGNGTCSNTRGGYECQ----------C 495
C+D +EC L D C G T EC C
Sbjct: 1080 ICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELC 1139
Query: 496 --SPGF-----TQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYAVAADGVH 547
PGF T G D++EC + CT +C NT GSF+C C G+A+ ++ +
Sbjct: 1140 PRGPGFATKEITNG-KPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERN 1198
Query: 548 CRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLC 606
C DIDEC P +C C N G + CKC EGY S +N C DI+EC+ LC
Sbjct: 1199 CTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYE--SGFMMMKN-CMDIDECQRDPLLC 1255
Query: 607 SGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
GGVC NT+GS+ C+C G + S + + CID
Sbjct: 1256 RGGVCHNTEGSYRCECPPGHQLSPNISACID 1286
Score = 343 bits (843), Expect = 2e-93
Identities = 217/683 (31%), Positives = 311/683 (45%), Gaps = 82/683 (12%)
Query: 7 DQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETK 66
D +C+ +GV +K CCCS+G AWG PCE CP + + LC G NP+T +
Sbjct: 1677 DTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILE 1736
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
IDEC +P LC+ G C +T FQC C GY + + +C DV+EC P G C
Sbjct: 1737 DIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECE--TPGICGPGTC 1794
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDE--C-----GDQRICDHGDCRNTIGSYRCECK 179
N G + C CPP Y + C D+ C D + CD G+ + C C
Sbjct: 1795 YNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCD-GELLFNMTKKMCCC- 1852
Query: 180 PGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREG 239
Y + + ++C P C + ++ G VD++ECRE
Sbjct: 1853 -SYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLP-------VDIDECREI 1904
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGG 299
VC NG C N VGSFRCEC G+ C D+DEC P C R N C NT G
Sbjct: 1905 PGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGP-VCQR--NAECINTAGS 1961
Query: 300 YECSCGAGWKLVGR-RCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV 358
Y C C G++ +C DR+EC+E+P +C+ G+C + G + C C G++ + +C+
Sbjct: 1962 YRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCL 2021
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
D E D G C + C C+ G F+ +
Sbjct: 2022 D-INECERDACGNGTCRNT----IGSFNCRCNHG-----------------FI------L 2053
Query: 419 GRPNLTQDLDECRV-RPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPR 477
N D+DEC ++C G+C+NT GSF+C+C +GY +APDG +CVD +EC L+PR
Sbjct: 2054 SHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPR 2113
Query: 478 ICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRCTCP 536
C GTC N G Y C C PG++ ++ C D+DEC E C C NT GSF+C CP
Sbjct: 2114 KCAPGTCQNLDGSYRCICPPGYSL-QNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCP 2172
Query: 537 YGYAVAADGVHCRDI--DECVQ--EPRVCPHACENVVGSYICKCP---EGYRRTS--APQ 587
G+++++ G C+D+ C E C C C EG+ P
Sbjct: 2173 EGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPT 2232
Query: 588 DSENACEDI------------NECEEQEDLCSGGVC-----INTDGSFLCDCDAGFEPSE 630
+ + A I + + ++ VC INTDGS+ C+C G+ +
Sbjct: 2233 EPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYTLA- 2291
Query: 631 DGTDCIDRRTGTCYRSLVSGRCE 653
G +C+D + +G C+
Sbjct: 2292 -GNECVDTDECSVGNPCGNGTCK 2313
Score = 318 bits (782), Expect = 4e-86
Identities = 189/546 (34%), Positives = 252/546 (46%), Gaps = 41/546 (7%)
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCR 168
D+DEC P QC+N G++ C CP GY L + EC D DEC C +G C+
Sbjct: 2258 DMDECK--EPDVCKHGQCINTDGSYRCECPFGYTLAGN--ECVDTDECSVGNPCGNGTCK 2313
Query: 169 NTIGSYRCECKPGYTLRENV-CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN 227
N IG + C C+ G+ + C D++EC++ +C C N G+Y C C G+ +
Sbjct: 2314 NVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAF-RCVNTYGSYECKCPVGYVLRED 2372
Query: 228 ND-CVDVNECREGGMVC--RNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHP 284
C D +EC EG C + C+N +G++ C C PGY DG C D +EC P
Sbjct: 2373 RRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGI 2432
Query: 285 CGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDE--C--KELPYVCA-GGECRNFN 337
C N C NT G Y C C G+ + C+D E C + L +C G RN
Sbjct: 2433 CE---NGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPV 2489
Query: 338 GGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGR 397
C C G + +C + GR + EC
Sbjct: 2490 TKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADI--DECKVIHDVCRNG 2547
Query: 398 YCERCPAPDSAEFMRICQGGMGRPNLTQ----DLDECRVRPDVCVGGRCVNTDGSFRCEC 453
C D + IC+ G P++T DL+EC P C C NT+GS++C C
Sbjct: 2548 ECVN----DRGSYHCICKTGY-TPDITGTSCVDLNECNQAPKPC-NFICKNTEGSYQCSC 2601
Query: 454 PDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDEC 513
P GY+L DG SC D DECA C C NT GG+ C+C PGFTQ +C+D +EC
Sbjct: 2602 PKGYILQEDGRSCKDLDECATKQHNC-QFLCVNTIGGFTCKCPPGFTQH-HTSCIDNNEC 2659
Query: 514 AEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGS 571
C + C NT GSF C C G+++ G C D+DEC R C H C+N++G
Sbjct: 2660 TSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHR-CQHGCQNIIGG 2718
Query: 572 YICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSED 631
Y C CP+GY + N C D NEC +C G C NT GS+ C C AGF+ +
Sbjct: 2719 YRCSCPQGYLQ----HYQWNQCVDENECLSAH-ICGGASCHNTLGSYKCMCPAGFQYEQF 2773
Query: 632 GTDCID 637
C D
Sbjct: 2774 SGGCQD 2779
Score = 317 bits (778), Expect = 1e-85
Identities = 233/764 (30%), Positives = 308/764 (40%), Gaps = 82/764 (10%)
Query: 135 CRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYT---LRENVCRD 191
C CP G ++ PS + C + R + G C + C C+ GY + VC
Sbjct: 231 CTCPSG-QIAPSCGS-RSIQHC-NIRCMNGGSCSDD----HCLCQKGYIGTHCGQPVCES 283
Query: 192 VDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE--GGMVCRNGRCR 249
C C G C+ ++ GP + C+ G+VC C
Sbjct: 284 --GCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCC 341
Query: 250 NTVG---SFRCECAP--------GYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
TVG CE P G+ C+DVDEC +P C + GN C NT G
Sbjct: 342 ATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLC-QGGN--CINTVG 398
Query: 299 GYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
+EC C AG KL V ++C D DEC +P +C GGEC N Y C+CP G+
Sbjct: 399 SFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTR 458
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYC----ERCPAPDSAEFMR 412
C+D R CY GRC P + + +CCC G W E CP + +F +
Sbjct: 459 CIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNK 518
Query: 413 ICQGGM---GRPN-----LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
+C M GRP L V P G + P P L
Sbjct: 519 LCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSRE--PPRVL 576
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
D C L +C NG C T G Y C+C+ GF C+DVDEC E C
Sbjct: 577 PVNVTDYCQLVRYLCQNGRCIPTPGSYRCECNKGFQLDLRGECIDVDEC-EKNPCAGGEC 635
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRT 583
N GS+ C C GY CRDIDEC+Q R+C + C N GS+ C C G+ T
Sbjct: 636 INNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVT 695
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRR---- 639
+D +N CED++EC + ++C G+CIN DGSF C C GF+ + DG C D
Sbjct: 696 ---RDGKN-CEDMDECSIR-NMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECET 750
Query: 640 -----TGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTL-GAAW 693
G C + S RCE G + QC L GA
Sbjct: 751 PGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVT 810
Query: 694 GSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAA 753
SEC C A A + C P +D++ECA
Sbjct: 811 KSEC--CCASTEYAFGEPCQP---CPAQNSAEYQALCSSGPGMTSAG-----SDINECAL 860
Query: 754 IPGLC-------APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ-LCHNTDGSYD 803
P +C G ++C+C GY G+ C D++EC + CD C NT GS+
Sbjct: 861 DPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFV 920
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSC 847
C C G+ D C D+DECE + +C N+ GS+ C C
Sbjct: 921 CTCPKGFIYKPDLKTCEDIDECE-SSPCINGVCKNSPGSFICEC 963
Score = 293 bits (719), Expect = 2e-78
Identities = 194/556 (34%), Positives = 253/556 (45%), Gaps = 73/556 (13%)
Query: 63 NETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRG 122
NE DEC + C GTC + GF+C C+ G+E C D++EC+ + P
Sbjct: 2293 NECVDTDECSV-GNPCGNGTCKNVIGGFECTCEEGFE-PGPMMTCEDINECA--QNPLLC 2348
Query: 123 MAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHG--DCRNTIGSYRCECK 179
+CVN G++EC+CP GY L C+D DEC + + C +C+N IG+Y C C
Sbjct: 2349 AFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICG 2408
Query: 180 PGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNE- 235
PGY R + C D +EC +C NG C N G+Y C C+DGF A PN D C+D E
Sbjct: 2409 PGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREG 2468
Query: 236 -CREGGM--VCRNGRC-RNTVGSFRCECAPGY------------------TLTADGR--- 270
C + +C+ G RN V C C G L GR
Sbjct: 2469 YCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFM 2528
Query: 271 -NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK--LVGRRCVDRDECKELPYV 327
N D+DEC + C R+G C N G Y C C G+ + G CVD +EC + P
Sbjct: 2529 TNGADIDECKVIHDVC-RNGE--CVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKP 2585
Query: 328 CAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPEC 387
C C+N G Y C CP G+ + C D DE A + H + L C
Sbjct: 2586 C-NFICKNTEGSYQCSCPKGYILQEDGRSCKD------LDEC-ATKQHNCQFL------C 2631
Query: 388 CCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDG 447
+ G G C +CP P + C + T D++ C + G C NT G
Sbjct: 2632 VNTIG---GFTC-KCP-PGFTQHHTSC---IDNNECTSDINLCGSK------GICQNTPG 2677
Query: 448 SFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QT 506
SF CEC G+ L G SC D DEC + R C +G C N GGY C C G+ Q
Sbjct: 2678 SFTCECQRGFSLDQTGSSCEDVDECEGNHR-CQHG-CQNIIGGYRCSCPQGYLQHYQWNQ 2735
Query: 507 CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
CVD +EC CHNT GS++C CP G+ C+DI+EC C + C
Sbjct: 2736 CVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCS 2795
Query: 567 NVVGSYICKCPEGYRR 582
N G Y+C CP GY R
Sbjct: 2796 NTEGGYLCGCPPGYFR 2811
Score = 241 bits (590), Expect = 7e-63
Identities = 180/563 (31%), Positives = 247/563 (43%), Gaps = 65/563 (11%)
Query: 34 PCEACPPRGSPAHTALCGEKPGEYINPVTNETK--PI---DECDIMPQLCKPGTCHDTPT 88
P PP P P EY+ P + P+ D C ++ LC+ G C TP
Sbjct: 542 PVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPG 601
Query: 89 GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD 148
++C C+ G++ D C DVDEC + PC G +C+N G++ C+C GY+ T +
Sbjct: 602 SYRCECNKGFQLDLRGE-CIDVDECE--KNPCAG-GECINNQGSYTCQCRAGYQSTLTRT 657
Query: 149 ECEDVDEC-GDQRICDHGDCRNTIGSYRCECKPGY--TLRENVCRDVDECSRPRPVCRNG 205
EC D+DEC + RIC++G C NT GS+ C C G+ T C D+DECS R +C NG
Sbjct: 658 ECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECS-IRNMCLNG 716
Query: 206 TCENLPGAYLCHCDDGFK-AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYT 264
C N G++ C C GF+ A C D+NEC G +C NGRC NT GS+RCEC PG
Sbjct: 717 MCINEDGSFKCICKPGFQLASDGRYCKDINECETPG-ICMNGRCVNTDGSYRCECFPGLA 775
Query: 265 LTADGRNCRDVDECDELPHPC-GRDGNPSCTNTNGG----YECSCGAGWKLVGRRC--VD 317
+ DGR C D + C G C G EC C + G C
Sbjct: 776 VGLDGRVCVDT----HMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCP 831
Query: 318 RDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER---KELCYDEWEAGRC 374
E +C+ G G + EC +C + R K +C +E
Sbjct: 832 AQNSAEYQALCSSGPGMTSAGSDINECALDPDICPN-GICENLRGTYKCICNSGYEVDST 890
Query: 375 HRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC-QGGMGRPNL--TQDLDECR 431
+ + EC + C P F+ C +G + +P+L +D+DEC
Sbjct: 891 GKN---CVDINECVLNSLLCDNGQCRNTP----GSFVCTCPKGFIYKPDLKTCEDIDECE 943
Query: 432 VRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDAD-----ECALDPR--ICGNGT- 483
P C+ G C N+ GSF CEC L P C++ + +D R I NG
Sbjct: 944 SSP--CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGAT 1001
Query: 484 ----CSNTRG---GYECQ-------CSPGFTQGPDQTCVDVDECAEGRASC-TFRCHNTA 528
C ++ G G C C G+++ C D+DEC C C NT
Sbjct: 1002 LKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTR 1061
Query: 529 GSFRCTCPYGYAVAADGVHCRDI 551
GSF+C CP G + A G C DI
Sbjct: 1062 GSFKCQCPSGMTLDATGRICLDI 1084
Score = 234 bits (572), Expect = 1e-60
Identities = 154/483 (31%), Positives = 212/483 (43%), Gaps = 46/483 (9%)
Query: 193 DECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTV 252
D C R +C+NG C PG+Y C C+ GF+ +C+DV+EC + C G C N
Sbjct: 582 DYCQLVRYLCQNGRCIPTPGSYRCECNKGFQLDLRGECIDVDECEKN--PCAGGECINNQ 639
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV- 311
GS+ C+C GY T CRD+DEC + C N C NT+G + C C AG+ +
Sbjct: 640 GSYTCQCRAGYQSTLTRTECRDIDECLQNGRIC---NNGRCINTDGSFHCVCNAGFHVTR 696
Query: 312 -GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWE 370
G+ C D DEC + +C G C N +G + C C G++ C D +E E
Sbjct: 697 DGKNCEDMDEC-SIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKD------INECE 749
Query: 371 A-GRCHRARPLQL-ARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLD 428
G C R + C C G A G C C GG R + L
Sbjct: 750 TPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCV---DTHMRSTCYGGYKRGQCIKPLF 806
Query: 429 ECRVRPDVCVGGRCVNTDGSF--RCE-CP-----DGYVLAPDGLSCV----DADECALDP 476
+ + C C +T+ +F C+ CP + L G D +ECALDP
Sbjct: 807 GAVTKSECC----CASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDP 862
Query: 477 RICGNGTCSNTRGGYECQCSPGF-TQGPDQTCVDVDECAEGRASC-TFRCHNTAGSFRCT 534
IC NG C N RG Y+C C+ G+ + CVD++EC C +C NT GSF CT
Sbjct: 863 DICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCT 922
Query: 535 CPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACE 594
CP G+ D C DIDEC P + C+N GS+IC+C S ++ C
Sbjct: 923 CPKGFIYKPDLKTCEDIDECESSPCI-NGVCKNSPGSFICECSS----ESTLDPTKTICI 977
Query: 595 DINECEEQEDLCSGGVCINTDGSFL---CDCDAGFEPSEDGTDC-IDRRTGTCYRSLVSG 650
+ + + + G IN +G+ L C G T C +D G Y +
Sbjct: 978 ETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGT 1037
Query: 651 RCE 653
+CE
Sbjct: 1038 QCE 1040
Score = 216 bits (528), Expect = 2e-55
Identities = 149/478 (31%), Positives = 198/478 (41%), Gaps = 71/478 (14%)
Query: 66 KPIDECDIMPQLC--KPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGM 123
K DEC+ C K C + + C C GY+ C D +EC C
Sbjct: 2377 KDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICEN- 2435
Query: 124 AQCVNLPGAFECRCPPGYRLTPSLDECEDVDE--CGD---QRICDHGDC-RNTIGSYRCE 177
+C+N G++ C C G+ +P+ DEC D E C Q +C G RN + C
Sbjct: 2436 GRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECC 2495
Query: 178 CK--------------PGYTLRENVC----------RDVDECSRPRPVCRNGTCENLPGA 213
C G + +C D+DEC VCRNG C N G+
Sbjct: 2496 CDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGS 2555
Query: 214 YLCHCDDGFKAG-PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNC 272
Y C C G+ CVD+NEC + C N C+NT GS++C C GY L DGR+C
Sbjct: 2556 YHCICKTGYTPDITGTSCVDLNECNQAPKPC-NFICKNTEGSYQCSCPKGYILQEDGRSC 2614
Query: 273 RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAG-G 331
+D+DEC H C C NT GG+ C C G+ C+D +EC +C G
Sbjct: 2615 KDLDECATKQHNC----QFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKG 2670
Query: 332 ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAG-RCHRARPLQLARPECCCS 390
C+N G + CEC G+ D+T + C D DE E RC + C C
Sbjct: 2671 ICQNTPGSFTCECQRGFSLDQTGSSCED------VDECEGNHRCQHGCQNIIGGYRCSCP 2724
Query: 391 EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFR 450
+G +C D +EC + +C G C NT GS++
Sbjct: 2725 QGYLQHYQWNQCV----------------------DENEC-LSAHICGGASCHNTLGSYK 2761
Query: 451 CECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV 508
C CP G+ C D +EC C G CSNT GGY C C PG+ + CV
Sbjct: 2762 CMCPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGCPPGYFRIGQGHCV 2818
Score = 140 bits (339), Expect = 2e-32
Identities = 113/358 (31%), Positives = 146/358 (40%), Gaps = 39/358 (10%)
Query: 210 LPGAYLCH-CDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGS-FRCECAPGYTLTA 267
L +Y H D +AG + R GG + N GS + C PG+
Sbjct: 147 LLASYTSHGADANLEAGNVKETRASRAKRRGGGGHDALKGPNVCGSRYNAYCCPGWKTLP 206
Query: 268 DGRNCRDVDECDELPHPCGRDG---NPS-CTNTNGGYECSCGA-GWKLVGRRCVDRDECK 322
G C V C H CG DG P+ CT +G SCG+ + RC++ C
Sbjct: 207 GGNQCI-VPICR---HSCG-DGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCS 261
Query: 323 ELPYVCAGGECRNFNGGYVCE--CPAGWRF--DKTAAVCVDERKELCYDEWEAGRCHRAR 378
+ +C G G VCE C G R A C ++ G C
Sbjct: 262 DDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVI 321
Query: 379 PLQLARPE----------CCCSEGAAWGRYCERCPAPDSAEFMRICQGGMG---RPNLTQ 425
Q+ + + CC + G AWG CE CPA C+ G R Q
Sbjct: 322 SNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHP-----CRRGFIPNIRTGACQ 376
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
D+DEC+ P +C GG C+NT GSF C+CP G+ L C D DEC+ P IC G C+
Sbjct: 377 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECT 436
Query: 486 NTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFRCHN----TAGSFRCTCPYG 538
NT Y C+C PGF PD T C+DV A RC N + +C C G
Sbjct: 437 NTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 494
Score = 128 bits (308), Expect = 1e-28
Identities = 99/330 (30%), Positives = 132/330 (40%), Gaps = 53/330 (16%)
Query: 411 MRICQGGMGRPNL-TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
M C G P+ ++ + C +R C+ G + D C C GY+ G ++
Sbjct: 230 MCTCPSGQIAPSCGSRSIQHCNIR---CMNGGSCSDD---HCLCQKGYIGTHCGQPVCES 283
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS---CTFR-CH 525
C R C+ T G QC + GP T + C +G+ S CT C
Sbjct: 284 G-CLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMC-QGQLSGIVCTKTLCC 341
Query: 526 NTAG---SFRCT--------CPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYI 573
T G C C G+ C+D+DEC P +C C N VGS+
Sbjct: 342 ATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFE 401
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGT 633
CKCP G++ Q CEDI+EC +C GG C NT S+ C C GF S DGT
Sbjct: 402 CKCPAGHKLNEVSQK----CEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGT 457
Query: 634 DCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAW 693
CID R G CY +L +GRC + +TK QCCC G W
Sbjct: 458 RCIDVRPGYCYTALTNGRCSNQLPQS--------------------ITKMQCCCDAGRCW 497
Query: 694 GSEC----ELCPAPGSPARLDLCTAVNLTP 719
E+CP + LC+ + P
Sbjct: 498 SPGVTVAPEMCPIRATEDFNKLCSVPMVIP 527
Score = 126 bits (305), Expect = 3e-28
Identities = 77/245 (31%), Positives = 102/245 (41%), Gaps = 19/245 (7%)
Query: 2 EWNEEDQSCAGAVGVPQTKYLCCCSVGHAW---GAPCEACPPRGSPAHTA--LCGEKPGE 56
E N+ + C + Y C C G+ G C+ + H LC G
Sbjct: 2578 ECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGG 2637
Query: 57 YINP-----VTNETKPID--ECDIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLCR 108
+ + T ID EC LC G C +TP F C C G+ D T C
Sbjct: 2638 FTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE 2697
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCR 168
DVDEC G C+ C N+ G + C CP GY ++C D +EC IC C
Sbjct: 2698 DVDECE-GNHRCQH--GCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCH 2754
Query: 169 NTIGSYRCECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGP 226
NT+GSY+C C G+ + C+D++EC + C G C N G YLC C G+
Sbjct: 2755 NTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGCPPGYFRIG 2813
Query: 227 NNDCV 231
CV
Sbjct: 2814 QGHCV 2818
Score = 120 bits (289), Expect = 2e-26
Identities = 66/194 (34%), Positives = 93/194 (47%), Gaps = 19/194 (9%)
Query: 7 DQSCAGAV-GVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNET 65
+Q C G + G+ TK LCC +VG AWG PCE CP + P + G N T
Sbjct: 323 NQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPC-------RRGFIPNIRTGAC 375
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ 125
+ +DEC +P LC+ G C +T F+C C G++ + S C D+DECS C G +
Sbjct: 376 QDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEG-GE 434
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRN----TIGSYRCEC--- 178
C N ++ C+CPPG+ +P C DV +G C N +I +C C
Sbjct: 435 CTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 494
Query: 179 ---KPGYTLRENVC 189
PG T+ +C
Sbjct: 495 RCWSPGVTVAPEMC 508
Score = 97.5 bits (232), Expect = 2e-19
Identities = 46/124 (37%), Positives = 65/124 (52%), Gaps = 12/124 (9%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYRPAGEV--CADVDECAVRPPPC-DQLCH 796
D+DEC P +C PG +RC+C G+ + ++ C DV+EC + P C C
Sbjct: 1369 DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCE 1428
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKR 854
NT GS+ C C GY + C D++ECE H C +C+NT GS++CSC G+
Sbjct: 1429 NTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGD 1488
Query: 855 GDAC 858
G C
Sbjct: 1489 GIKC 1492
Score = 97.1 bits (231), Expect = 2e-19
Identities = 48/122 (39%), Positives = 61/122 (50%), Gaps = 12/122 (9%)
Query: 747 DVDECAAIPGLCA-------PGRFRCVCGPGYRPAGEV---CADVDECAVRPPPC-DQLC 795
D+DEC P LC PG F C C GY + C D+DEC P C +C
Sbjct: 1201 DIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVC 1260
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKR 854
HNT+GSY C C G++L + + C D++ECE H C C N G Y+C+C GY
Sbjct: 1261 HNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHST 1320
Query: 855 GD 856
D
Sbjct: 1321 PD 1322
Score = 96.3 bits (229), Expect = 4e-19
Identities = 47/113 (41%), Positives = 57/113 (50%), Gaps = 9/113 (7%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNT 798
D+DECA C G F C C PG+ C D +EC C +C NT
Sbjct: 2616 DLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNT 2675
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
GS+ C C+ G+ LD+ G++C DVDECE H CQ C N G Y CSC GY
Sbjct: 2676 PGSFTCECQRGFSLDQTGSSCEDVDECE-GNHRCQHGCQNIIGGYRCSCPQGY 2727
Score = 94.3 bits (224), Expect = 2e-18
Identities = 45/115 (39%), Positives = 58/115 (50%), Gaps = 10/115 (8%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ-LCH 796
D+DEC P LC G +RC C PG++ P C D++EC + C C
Sbjct: 1244 DIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCV 1303
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
N G Y C C GY D C D+DEC C+ C+N+EGSYECSC+ G+
Sbjct: 1304 NLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGF 1358
Score = 91.5 bits (217), Expect = 1e-17
Identities = 44/118 (37%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 747 DVDECAAIP---GLCA--PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQ-LCHNT 798
DVDEC P G C G + C C GY+ C D+DEC C+ C NT
Sbjct: 621 DVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINT 680
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
DGS+ C+C G+ + DG NC D+DEC +C N +GS++C C+ G++ D
Sbjct: 681 DGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASD 738
Score = 90.2 bits (214), Expect = 3e-17
Identities = 49/125 (39%), Positives = 62/125 (49%), Gaps = 15/125 (12%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYR-PAGEV-CADVDECAVRPPPCDQ--LC 795
DV+EC P +C G F C C GY G+ C D++EC + C + +C
Sbjct: 1411 DVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVC 1470
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEK 853
NT GS+ C C G+ DG C D+DEC TH C Q C NT GSY C C++GY
Sbjct: 1471 TNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTG 1528
Query: 854 RGDAC 858
G C
Sbjct: 1529 DGFTC 1533
Score = 85.8 bits (203), Expect = 6e-16
Identities = 38/94 (40%), Positives = 55/94 (58%), Gaps = 5/94 (5%)
Query: 765 CVCGPGYRPAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
C GPG AG +D++ECA+ P C +C N G+Y C+C +GYE+D G NC D++
Sbjct: 842 CSSGPGMTSAG---SDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDIN 898
Query: 824 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
EC ++ C C NT GS+ C+C G+ + D
Sbjct: 899 ECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPD 932
Score = 84.2 bits (199), Expect = 2e-15
Identities = 41/100 (41%), Positives = 52/100 (52%), Gaps = 5/100 (5%)
Query: 760 PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG +RC C G++ GE C DVDEC P + C N GSY C CR GY+
Sbjct: 600 PGSYRCECNKGFQLDLRGE-CIDVDECEKNPCAGGE-CINNQGSYTCQCRAGYQSTLTRT 657
Query: 818 NCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
CRD+DEC ++ C C NT+GS+ C C G+ D
Sbjct: 658 ECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRD 697
Score = 83.0 bits (196), Expect = 4e-15
Identities = 39/102 (38%), Positives = 51/102 (50%), Gaps = 3/102 (2%)
Query: 761 GRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
G +RC C GY + C D +EC CHNT GSY C+C G++ ++
Sbjct: 2717 GGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGG 2776
Query: 819 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
C+D++EC C CSNTEG Y C C GY + G CV
Sbjct: 2777 CQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCV 2818
Score = 71.7 bits (168), Expect = 1e-11
Identities = 41/112 (36%), Positives = 51/112 (45%), Gaps = 8/112 (7%)
Query: 746 ADVDECAAIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTDGS 801
+D++ C + G+C PG F C C G+ G C DVDEC C C N G
Sbjct: 2661 SDINLCGS-KGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHR-CQHGCQNIIGG 2718
Query: 802 YDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYE 852
Y C C GY C D +EC H C C NT GSY+C C G++
Sbjct: 2719 YRCSCPQGYLQHYQWNQCVDENEC-LSAHICGGASCHNTLGSYKCMCPAGFQ 2769
Score = 70.1 bits (164), Expect = 3e-11
Identities = 32/76 (42%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Query: 778 CADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ-QI 835
C DVDEC P C C NT GS++C C G++L+E C D+DEC C+
Sbjct: 375 CQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGE 434
Query: 836 CSNTEGSYECSCEDGY 851
C+NT SY C C G+
Sbjct: 435 CTNTVSSYFCKCPPGF 450
Score = 69.7 bits (163), Expect = 4e-11
Identities = 43/118 (36%), Positives = 53/118 (44%), Gaps = 14/118 (11%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ-LCH 796
DVDEC AIPGLC G F C C G++ + C D+DEC+ P C+ C
Sbjct: 377 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECT 436
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSN----TEGSYECSCEDG 850
NT SY C C G+ DG C DV T CSN + +C C+ G
Sbjct: 437 NTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 494
Score = 50.4 bits (115), Expect = 3e-05
Identities = 38/155 (24%), Positives = 52/155 (33%), Gaps = 12/155 (7%)
Query: 560 VCPHACENVVGSY--ICKCPEGYRRTSAPQDSENACE----DINECEEQEDLCSGGVCIN 613
+C H+C + S +C CP G S S C + C + LC G
Sbjct: 215 ICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGT 274
Query: 614 TDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXX 673
G +C+ +G C+ C +CE +
Sbjct: 275 HCGQPVCESGC-----LNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQ 329
Query: 674 XXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPAR 708
TK CC T+G AWG CE+CPA P R
Sbjct: 330 LSGIV-CTKTLCCATVGRAWGHPCEMCPAQPHPCR 363
Score = 43.6 bits (98), Expect = 0.003
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE 852
CR G+ + C+DVDEC+ CQ C NT GS+EC C G++
Sbjct: 362 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHK 409
Score = 39.1 bits (87), Expect = 0.066
Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 3/73 (4%)
Query: 790 PCDQLCHNTDGSYDCLCR--TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECS 846
PC+ Y LC G+ + D+DEC+ CQ C NT GS++C
Sbjct: 1704 PCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCR 1763
Query: 847 CEDGYEKRGDACV 859
C GY D V
Sbjct: 1764 CPTGYYLNEDTRV 1776
>L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein.
Length = 2871
Score = 719 bits (1777), Expect = 0.0
Identities = 342/871 (39%), Positives = 467/871 (53%), Gaps = 66/871 (7%)
Query: 6 EDQSCAGAVGVPQTKYLCCCS--VGHAWGAPCEACPPRGSPAHTALCG-EKPGEYINPVT 62
++Q+C G + TK +CCCS +G AW PCE CP + LCG ++PG I+ T
Sbjct: 1702 DNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYT 1761
Query: 63 NETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRG 122
IDEC +P +C+ G C + F+C C G+ +++ +C D+DEC G P C+
Sbjct: 1762 GLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNG-PVCQR 1820
Query: 123 MAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCECKPG 181
A+C+N G++ C C PGYR T S +C D +EC + IC HG C +T+GS+ C C G
Sbjct: 1821 NAECINTAGSYRCDCKPGYRFT-STGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTG 1879
Query: 182 YTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREG 239
+ ++ +C D++EC R C NGTC N G++ C C+ GF NNDC+DV+EC G
Sbjct: 1880 FKTNDDQTMCLDINECERD--ACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASG 1937
Query: 240 -GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
G +CRNG+C NTVGSF+C+C GY + DGR C D++EC P C +C N +G
Sbjct: 1938 NGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPG---TCQNLDG 1994
Query: 299 GYECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV 358
Y C C G+ L +C D DEC E P +CA G C N G + C CP G+ + C
Sbjct: 1995 SYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQ 2054
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCS-EGAAWGRYCERCPAPDSAEFMRICQGG 417
D R CY ++E G+C + ++ ECCC+ +G WG CE CP F +IC G
Sbjct: 2055 DLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYG 2114
Query: 418 ----MGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
+G + D+DEC+ PDVC G+C+NTDGS+RCECP GY LA G CVD DEC+
Sbjct: 2115 SGIIVGPDDSAVDMDECK-EPDVCKHGQCINTDGSYRCECPFGYTLA--GNECVDTDECS 2171
Query: 474 LDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRC 533
+ CGNGTC N GG+EC C GF GP TC D++ECA+ C FRC NT GS+ C
Sbjct: 2172 VG-NPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYEC 2230
Query: 534 TCPYGYAVAADGVHCRDIDECVQEPRVCPH---ACENVVGSYICKCPEGYRRTSAPQDSE 590
CP GY + D C+D DEC + C C+N++G+Y+C C GY+R D E
Sbjct: 2231 KCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRR---PDGE 2287
Query: 591 NACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSG 650
C D NEC+ + +C G C+NT GS+ C+C+ GF S + +C+D R G C+ ++
Sbjct: 2288 -GCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQN 2346
Query: 651 RCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLD 710
C+ VTK++CCC G WG CE+CP G+ A
Sbjct: 2347 MCQ------------------IGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKK 2388
Query: 711 LCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCAPGRFRCVCGPG 770
LC V DV C + G + C+C G
Sbjct: 2389 LCP--------------HGRGFMTNGADIDECKVIHDV--CRNGECVNDRGSYHCICKTG 2432
Query: 771 YRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERD 828
Y P G C D++EC P PC+ +C NT+GSY C C GY L EDG +C+D+DEC
Sbjct: 2433 YTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATK 2492
Query: 829 THTCQQICSNTEGSYECSCEDGYEKRGDACV 859
H CQ +C NT G + C C G+ + +C+
Sbjct: 2493 QHNCQFLCVNTIGGFTCKCPPGFTQHHTSCI 2523
Score = 454 bits (1119), Expect = e-127
Identities = 260/735 (35%), Positives = 349/735 (47%), Gaps = 91/735 (12%)
Query: 161 ICDHGDCRNTIGSYRCECKPGYTLR-ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCD 219
+C +G C T GSYRCEC G+ L C DVDEC + P C G C N G+Y C C
Sbjct: 459 LCQNGRCIPTPGSYRCECNKGFQLDLRGECIDVDECEK-NP-CAGGECINNQGSYTCQCR 516
Query: 220 DGFKAG-PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC 278
G+++ +C D++EC + G +C NGRC NT GSF C C G+ +T DG+NC D+DEC
Sbjct: 517 AGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDEC 576
Query: 279 DELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNF 336
+ + C N C N +G ++C C G++L GR C D +EC E P +C G C N
Sbjct: 577 S-IRNMCL---NGMCINEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNGRCVNT 631
Query: 337 NGGYVCECPAGWRFDKTAAVCVDER-KELCYDEWEAGRCHRARPLQLARPECCC-SEGAA 394
+G Y CEC G VCVD + CY ++ G+C + + + ECCC S A
Sbjct: 632 DGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYA 691
Query: 395 WGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECP 454
+G C+ CPA +SAE+ +C G G + D++EC + PD+C G C N G+++C C
Sbjct: 692 FGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICN 751
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDEC 513
GY + G +CVD +EC L+ +C NG C NT G + C C GF PD +TC D+DEC
Sbjct: 752 SGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC 811
Query: 514 AEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE-NVVG-- 570
E C N+ GSF C C + C + + V CE N+ G
Sbjct: 812 -ESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGAT 870
Query: 571 --SYICK------------------CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV 610
S C C +GY R Q CEDI+ECE +C G+
Sbjct: 871 LKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQ-----CEDIDECEVFPGVCKNGL 925
Query: 611 CINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXX 670
C+NT GSF C C +G G C+D R TC+ C
Sbjct: 926 CVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEEC------------------ 967
Query: 671 XXXXXXXGHVTKAQCCCTLGAAWGS-ECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXX 729
G CCC++GAAWG+ ECE CP +P +LC
Sbjct: 968 --TLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCP---------------R 1010
Query: 730 XXXXXXXXXXXXLDVFADVDECAAIPGLCAPGR-------FRCVCGPGYRPAGEV--CAD 780
F D++EC IP LC G+ F+C C G+ E C D
Sbjct: 1011 GPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTD 1070
Query: 781 VDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD-EDGANCRDVDECERDTHTCQ-QICS 837
+DEC + P C + C NT G ++C C GYE NC D+DEC+RD C+ +C
Sbjct: 1071 IDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCH 1130
Query: 838 NTEGSYECSCEDGYE 852
NTEGSY C C G++
Sbjct: 1131 NTEGSYRCECPPGHQ 1145
Score = 442 bits (1090), Expect = e-123
Identities = 292/908 (32%), Positives = 403/908 (44%), Gaps = 138/908 (15%)
Query: 7 DQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETK 66
D C + K CC S+G AWG+PC C + P +CG+ Y + +
Sbjct: 859 DGRCEININGATLKSQCCSSLGAAWGSPCTLC--QVDP----ICGK---GYSRIKGTQCE 909
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDV-----------DECSW 115
IDEC++ P +CK G C +T F+C C G D T +C D+ +EC+
Sbjct: 910 DIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTL 969
Query: 116 ---GR---PPC-------RGMAQCVNLP----GAFECRCP--PGY---RLTPSLDECEDV 153
GR C G +C P +E CP PG+ +T +D+
Sbjct: 970 PIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDI 1029
Query: 154 DECG-DQRICDHGDCRNTIGSYRCECKPGYTL--RENVCRDVDECSRPRPVCRNGTCENL 210
+EC +C HG CRNTIGS++C C G+ L E C D+DEC +C G C N
Sbjct: 1030 NECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 1089
Query: 211 PGAYLCHCDDGFKAG--PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTAD 268
PG + C CD+G+++G +C+D++EC+ ++CR G C NT GS+RCEC PG+ L+ +
Sbjct: 1090 PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPN 1149
Query: 269 GRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPY 326
C D++EC+ H C N C N G Y+C+C G+ R CVD DEC +
Sbjct: 1150 ISACIDINECELSAHLC---PNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNG 1206
Query: 327 VCAGGECRNFNGGYVCECPAGWRF--DKTAAVCVDERKE-------------------LC 365
C C N G Y C C G+ D+ + +DE ++ LC
Sbjct: 1207 GCE-TFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLC 1265
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
YD + A + + EC + CE G G+ T
Sbjct: 1266 YDGFMASEDMKT---CVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCT- 1321
Query: 426 DLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGT 483
D++EC + C C NT GSF+C C G++ DG+ C D DEC+ +C +
Sbjct: 1322 DINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHAD 1379
Query: 484 CSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASC-TFRCHNTAGSFRCTCPYGYAVA 542
C NT G Y C C G+T G TC D+DEC+E C +C N G +RC C G+ +
Sbjct: 1380 CKNTMGSYRCLCKEGYT-GDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPS 1438
Query: 543 ADGVHCRDIDECVQEPRVCPH-ACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEE 601
ADG C DIDEC P +C C N+ G + C+C GY S C D+NEC +
Sbjct: 1439 ADGKACEDIDEC-SLPNICVFGTCHNLPGLFRCECEIGYEL----DRSGGNCTDVNECLD 1493
Query: 602 QEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXX 661
C G C+NT GS++CDC FE + C+D R+G CY + P
Sbjct: 1494 -PTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDI-----RPRGDNGDT 1547
Query: 662 XXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLCT-AVNLTPX 720
V+KA CCC+LG AWG+ CE+CPA + LC P
Sbjct: 1548 ACSNEIGVG---------VSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPN 1598
Query: 721 XXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCAPGR-------FRCVCGPGY-- 771
+ D+DEC +PGLC G+ F+C C GY
Sbjct: 1599 PITV-------------------ILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYL 1639
Query: 772 RPAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDE--CERD 828
VC DV+EC P C C+NT G+Y C+C Y G NC D+ C R+
Sbjct: 1640 NEDTRVCDDVNECET-PGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRN 1698
Query: 829 THTCQQIC 836
+ Q C
Sbjct: 1699 YYADNQTC 1706
Score = 429 bits (1057), Expect = e-119
Identities = 281/835 (33%), Positives = 364/835 (43%), Gaps = 109/835 (13%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P LC+ G CH+T ++C C G++ C D++EC C +CV
Sbjct: 1114 IDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPN-GRCV 1172
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR-- 185
NL G ++C C PGY TP C D+DEC C N+ GSY C C+PG+ L
Sbjct: 1173 NLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPD 1232
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCR 244
+ C D+DEC +C G C N+PG Y C C DGF A + CVDVNEC +C
Sbjct: 1233 QRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICL 1292
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
+G C NT GSF C C GY+ C D++EC+ H CG+ + CTNT G ++CSC
Sbjct: 1293 SGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGK--HAVCTNTAGSFKCSC 1350
Query: 305 GAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
GW G +C D DEC ++C+ +C+N G Y C C G+ D +DE E
Sbjct: 1351 SPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSE 1410
Query: 364 ---LCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGR 420
LC + G+C A C C G P+ D + C
Sbjct: 1411 NLNLCGN----GQCLNAP----GGYRCECDMGFV--------PSADG----KAC------ 1444
Query: 421 PNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG 480
+D+DEC + P++CV G C N G FRCEC GY L G +C D +EC LDP C
Sbjct: 1445 ----EDIDECSL-PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNEC-LDPTTCI 1498
Query: 481 NGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGY 539
+G C NT G Y C C P F P + CVD G R G C+ G
Sbjct: 1499 SGNCVNTPGSYICDCPPDFELNPTRVGCVDT---RSGNCYLDIRPRGDNGDTACSNEIGV 1555
Query: 540 AVAADGVHCRDIDECVQEP-RVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINE 598
V+ C + + P +CP A +C EG+R P EDI+E
Sbjct: 1556 GVSKASC-CCSLGKAWGTPCEMCP-AVNTSEYKILCPGGEGFR----PNPITVILEDIDE 1609
Query: 599 CEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRR---------TGTCYRSL-- 647
C+E LC GG CINT GSF C C G+ +ED C D GTCY ++
Sbjct: 1610 CQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGN 1669
Query: 648 VSGRCEP------------EXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCT--LGAAW 693
+ C P + ++TK CCC+ +G AW
Sbjct: 1670 YTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAW 1729
Query: 694 GSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAA 753
CE CP P + LC L V D+DEC
Sbjct: 1730 NKPCEQCPIPSTDEFATLC---------------GSQRPGFVIDIYTGLPV--DIDECRE 1772
Query: 754 IPGLC-------APGRFRCVCGPG--YRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSY 802
IPG+C G FRC C G Y VC D+DEC P C + C NT GSY
Sbjct: 1773 IPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRNAECINTAGSY 1831
Query: 803 DCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
C C+ GY G C D +EC+ + C C +T GS+ C C G++ D
Sbjct: 1832 RCDCKPGYRFTSTG-QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDD 1885
Score = 425 bits (1047), Expect = e-118
Identities = 215/564 (38%), Positives = 282/564 (50%), Gaps = 26/564 (4%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG-AFECRCPPGY 141
C+ G +C H C E WG PC C P AF CP G
Sbjct: 2061 CYAKFEGGKCSSPKSRNHSKQECCCALKGE-GWG-DPCE---LCPTEPDEAFRQICPYGS 2115
Query: 142 RLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRP 200
+ D+ D+DEC + +C HG C NT GSYRCEC GYTL N C D DECS P
Sbjct: 2116 GIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYTLAGNECVDTDECSVGNP 2175
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECA 260
C NGTC+N+ G + C C++GF+ GP C D+NEC + ++C RC NT GS+ C+C
Sbjct: 2176 -CGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAF-RCVNTYGSYECKCP 2233
Query: 261 PGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDR 318
GY L D R C+D DEC+E H C + C N G Y C CG G++ G CVD
Sbjct: 2234 VGYVLREDRRMCKDEDECEEGKHDC-TEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDE 2292
Query: 319 DECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCH--R 376
+EC+ P +C G C N G Y CEC G+ C+D R+ C+ E C
Sbjct: 2293 NECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGS 2352
Query: 377 ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDV 436
+ + + ECCC G WG +CE CP + F ++C G G D+DEC+V DV
Sbjct: 2353 SNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDV 2412
Query: 437 CVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCS 496
C G CVN GS+ C C GY G SCVD +EC P+ C N C NT G Y+C C
Sbjct: 2413 CRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPC-NFICKNTEGSYQCSCP 2471
Query: 497 PGF-TQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECV 555
G+ Q ++C D+DECA + +C F C NT G F C CP G+ C D +EC
Sbjct: 2472 KGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGF--TQHHTSCIDNNECT 2529
Query: 556 QEPRVC--PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCIN 613
+ +C C+N GS+ C+C G+ + + ++CED++ECE C G C N
Sbjct: 2530 SDINLCGSKGICQNTPGSFTCECQRGF----SLDQTGSSCEDVDECEGNH-RCQHG-CQN 2583
Query: 614 TDGSFLCDCDAGFEPSEDGTDCID 637
G + C C G+ C+D
Sbjct: 2584 IIGGYRCSCPQGYLQHYQWNQCVD 2607
Score = 422 bits (1040), Expect = e-117
Identities = 224/589 (38%), Positives = 291/589 (49%), Gaps = 48/589 (8%)
Query: 6 EDQSCAGAVGVPQTKYLCCCSVGHAWGAP-CEACPPRGSPAHTALCGEKPGEYINPVTNE 64
ED+ C + CCCSVG AWG CE CP R +P + LC PG +TN
Sbjct: 963 EDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNG 1022
Query: 65 T---KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
K I+EC ++P LC G C +T F+C CD G+ D+ C D+DEC C
Sbjct: 1023 KPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLC- 1081
Query: 122 GMAQCVNLPGAFECRCPPGYRL-TPSLDECEDVDEC-GDQRICDHGDCRNTIGSYRCECK 179
G QCVN PG FEC+C GY + C D+DEC D +C G C NT GSYRCEC
Sbjct: 1082 GRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECP 1141
Query: 180 PGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNEC 236
PG+ L N+ C D++EC +C NG C NL G Y C C+ G+ + P+ CVD++EC
Sbjct: 1142 PGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDEC 1201
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
C C N+ GS+ C C PG+ L D R+C D+DEC++ P+ C DG CTN
Sbjct: 1202 SIMNGGCET-FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNIC--DGG-QCTNI 1257
Query: 297 NGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTA 354
G Y C C G+ + CVD +EC P +C G C N G ++C C G+ K
Sbjct: 1258 PGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGK 1317
Query: 355 AVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC 414
C D +E E G H + C + ++ C
Sbjct: 1318 TGCTD------INECEIG-AHNC-----GKHAVCTNTAGSFKCSCS-------------- 1351
Query: 415 QGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
G +G DLDEC +C C NT GS+RC C +GY DG +C D DEC+
Sbjct: 1352 PGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY--TGDGFTCTDLDECS 1409
Query: 474 LDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFR 532
+ +CGNG C N GGY C+C GF D + C D+DEC+ CHN G FR
Sbjct: 1410 ENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFR 1469
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
C C GY + G +C D++EC+ +P C C N GSYIC CP +
Sbjct: 1470 CECEIGYELDRSGGNCTDVNECL-DPTTCISGNCVNTPGSYICDCPPDF 1517
Score = 390 bits (959), Expect = e-107
Identities = 234/680 (34%), Positives = 330/680 (48%), Gaps = 97/680 (14%)
Query: 19 TKYLCCC-SVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQL 77
TK CCC S +A+G PC+ CP + S + ALC PG +T+ I+EC + P +
Sbjct: 679 TKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPG-----MTSAGSDINECALDPDI 733
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRC 137
C G C + ++C C+ GYE D+T C D++EC C QC N PG+F C C
Sbjct: 734 CPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDN-GQCRNTPGSFVCTC 792
Query: 138 PPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL--RENVCRD---- 191
P G+ P L CED+DEC + C +G C+N+ GS+ CEC TL + +C +
Sbjct: 793 PKGFIYKPDLKTCEDIDEC-ESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKG 851
Query: 192 ------VD---ECSRPRPVCRNGTCENLPGAY-----LCH----CDDGFKAGPNNDCVDV 233
+D E + ++ C +L A+ LC C G+ C D+
Sbjct: 852 TCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDI 911
Query: 234 NECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV--DEC------DELPHP- 284
+EC VC+NG C NT GSF+C+C G TL A GR C D+ + C +E P
Sbjct: 912 DECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPI 971
Query: 285 CGRDGNPSCTNTNGG-----------------YE--CSCGAGW---KLVGRRCVDRD--E 320
GR +C + G YE C G G+ ++ + +D E
Sbjct: 972 AGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINE 1031
Query: 321 CKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKELCYDEWEAGRCHRARP 379
CK +P +C G+CRN G + C C +G+ D C D + + D G+C P
Sbjct: 1032 CKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT-P 1090
Query: 380 LQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG 439
EC C EG G M+ C D+DEC+ P +C G
Sbjct: 1091 GDF---ECKCDEGYESG-----------FMMMKNC----------MDIDECQRDPLLCRG 1126
Query: 440 GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGF 499
G C NT+GS+RCECP G+ L+P+ +C+D +EC L +C NG C N G Y+C C+PG+
Sbjct: 1127 GVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGY 1186
Query: 500 TQGPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEP 558
PD+ CVD+DEC+ C C N+ GS+ C+C G+A+ D C DIDEC P
Sbjct: 1187 HSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNP 1246
Query: 559 RVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGS 617
+C C N+ G Y C C +G+ A +D + C D+NEC+ ++C G C NT GS
Sbjct: 1247 NICDGGQCTNIPGEYRCLCYDGF---MASEDMK-TCVDVNECDLNPNICLSGTCENTKGS 1302
Query: 618 FLCDCDAGFEPSEDGTDCID 637
F+C CD G+ + T C D
Sbjct: 1303 FICHCDMGYSGKKGKTGCTD 1322
Score = 370 bits (911), Expect = e-102
Identities = 237/659 (35%), Positives = 310/659 (47%), Gaps = 84/659 (12%)
Query: 6 EDQSCAGAVGVPQTKYLCCCSV-GHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNE 64
E C+ +K CCC++ G WG PCE CP A +C G + P +
Sbjct: 2066 EGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGP-DDS 2124
Query: 65 TKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+DEC P +CK G C +T ++C C GY C D DECS G P C G
Sbjct: 2125 AVDMDECK-EPDVCKHGQCINTDGSYRCECPFGYTLAGNE--CVDTDECSVGNP-C-GNG 2179
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
C N+ G FEC C G+ P + CED++EC + C NT GSY C+C GY L
Sbjct: 2180 TCKNVIGGFECTCEEGFEPGPMMT-CEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVL 2238
Query: 185 REN--VCRDVDECSRPRPVC--RNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREG 239
RE+ +C+D DEC + C + C+NL G Y+C C G++ P+ + CVD NEC+
Sbjct: 2239 REDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTK 2298
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE--C--DELPHPCGRDGNPSCTN 295
+C NGRC NT GS+ CEC G+T + + C D E C + L + C +
Sbjct: 2299 PGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPV 2358
Query: 296 TNGGYECSCGAGW----------------KLV--GRRCV----DRDECKELPYVCAGGEC 333
T C G GW KL GR + D DECK + VC GEC
Sbjct: 2359 TKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGEC 2418
Query: 334 RNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRA-RPLQLARPECCCSEG 392
N G Y C C G+ D T CVD C++A +P C +EG
Sbjct: 2419 VNDRGSYHCICKTGYTPDITGTSCVD-----------LNECNQAPKPCNFI---CKNTEG 2464
Query: 393 AAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCE 452
+ +C P I Q GR +DLDEC + C CVNT G F C+
Sbjct: 2465 SY------QCSCPKGY----ILQED-GRS--CKDLDECATKQHNCQF-LCVNTIGGFTCK 2510
Query: 453 CPDGYVLAPDGLSCVDADECALDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQT---CV 508
CP G+ SC+D +EC D +CG+ G C NT G + C+C GF+ DQT C
Sbjct: 2511 CPPGFT--QHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSL--DQTGSSCE 2566
Query: 509 DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CEN 567
DVDEC EG C C N G +RC+CP GY C D +EC+ +C A C N
Sbjct: 2567 DVDEC-EGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECL-SAHICGGASCHN 2624
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
+GSY C CP G++ + C+DINEC + CS G C NT+G +LC C G+
Sbjct: 2625 TLGSYKCMCPAGFQY----EQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGCPPGY 2678
Score = 360 bits (885), Expect = 1e-98
Identities = 216/651 (33%), Positives = 304/651 (46%), Gaps = 71/651 (10%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C KPG + K I+EC+ P +C G C +T ++C C G +C D
Sbjct: 596 CICKPGFQLASDGRYCKDINECET-PGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVD 654
Query: 110 V---DECSWG--RPPC---------RGMAQCVNLPGAFECRCPP-------GYRLT---- 144
C G R C + C + AF C P Y+
Sbjct: 655 THMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG 714
Query: 145 PSLDEC-EDVDECG-DQRICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRP 200
P + D++EC D IC +G C N G+Y+C C GY + C D++EC
Sbjct: 715 PGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSL 774
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCRNGRCRNTVGSFRCEC 259
+C NG C N PG+++C C GF P+ C D++EC C NG C+N+ GSF CEC
Sbjct: 775 LCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSP--CINGVCKNSPGSFICEC 832
Query: 260 APGYTLTADGRNCRDVDE--CDE--LPHPC-----GRDGNPSCTNTNG---GYECS---- 303
+ TL C + + C + + C G C ++ G G C+
Sbjct: 833 SSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQV 892
Query: 304 ---CGAGW-KLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD 359
CG G+ ++ G +C D DEC+ P VC G C N G + C+CP+G D T +C+D
Sbjct: 893 DPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLD 952
Query: 360 ERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWG-RYCERCPAPDSAEFMRICQGGM 418
R E C+ +E C + CCCS GAAWG CE CP ++ E+ +C G
Sbjct: 953 IRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGP 1012
Query: 419 G--RPNLT------QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDAD 470
G +T +D++EC++ P +C G+C NT GSF+C C G+ L + +C D D
Sbjct: 1013 GFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDID 1072
Query: 471 ECALDPRICGNGTCSNTRGGYECQCSPGFTQG--PDQTCVDVDECAEGRASCTFR-CHNT 527
EC + P +CG G C NT G +EC+C G+ G + C+D+DEC C CHNT
Sbjct: 1073 ECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNT 1132
Query: 528 AGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAP 586
GS+RC CP G+ ++ + C DI+EC +CP+ C N++G Y C C GY T
Sbjct: 1133 EGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHST--- 1189
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+EC C C N++GS+ C C GF D C D
Sbjct: 1190 -PDRLFCVDIDECSIMNGGCE-TFCTNSEGSYECSCQPGFALMPDQRSCTD 1238
Score = 348 bits (856), Expect = 4e-95
Identities = 236/691 (34%), Positives = 310/691 (44%), Gaps = 100/691 (14%)
Query: 24 CCSVGHAWGAPC---EACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKP 80
C V PC E +GS +T C + G E + IDEC ++C
Sbjct: 488 CIDVDECEKNPCAGGECINNQGS--YTCQC--RAGYQSTLTRTECRDIDECLQNGRICNN 543
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
G C +T F C C+ G+ C D+DECS GM C+N G+F+C C PG
Sbjct: 544 GRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGM--CINEDGSFKCICKPG 601
Query: 141 YRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYT--LRENVCRDV------ 192
++L C+D++EC IC +G C NT GSYRCEC PG L VC D
Sbjct: 602 FQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTC 661
Query: 193 ------DECSRP-------RPVCRNGT-------CENLP----GAYLCHCDDGFKAGPNN 228
+C +P C T C+ P Y C G G +
Sbjct: 662 YGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG--PGMTS 719
Query: 229 DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRD 288
D+NEC +C NG C N G+++C C GY + + G+NC D++EC C
Sbjct: 720 AGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLC--- 776
Query: 289 GNPSCTNTNGGYECSCGAG--WKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPA 346
N C NT G + C+C G +K + C D DEC+ P C G C+N G ++CEC +
Sbjct: 777 DNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSP--CINGVCKNSPGSFICECSS 834
Query: 347 GWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPD 406
D T +C++ K C+ GRC + +CC S GAAWG C C
Sbjct: 835 ESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDP 894
Query: 407 SAEFMRICQGGMGRPNLTQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
IC G R TQ D+DEC V P VC G CVNT GSF+C+CP G L G
Sbjct: 895 ------ICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGR 948
Query: 465 SCVDA-----------DECAL--------DPRICGNGTCSNTRGGYECQ----------C 495
C+D +EC L D C G T EC C
Sbjct: 949 ICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELC 1008
Query: 496 --SPGF-----TQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYAVAADGVH 547
PGF T G D++EC + CT +C NT GSF+C C G+A+ ++ +
Sbjct: 1009 PRGPGFATKEITNG-KPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERN 1067
Query: 548 CRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLC 606
C DIDEC P +C C N G + CKC EGY S +N C DI+EC+ LC
Sbjct: 1068 CTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYE--SGFMMMKN-CMDIDECQRDPLLC 1124
Query: 607 SGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
GGVC NT+GS+ C+C G + S + + CID
Sbjct: 1125 RGGVCHNTEGSYRCECPPGHQLSPNISACID 1155
Score = 343 bits (843), Expect = 2e-93
Identities = 217/683 (31%), Positives = 311/683 (45%), Gaps = 82/683 (12%)
Query: 7 DQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETK 66
D +C+ +GV +K CCCS+G AWG PCE CP + + LC G NP+T +
Sbjct: 1546 DTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILE 1605
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
IDEC +P LC+ G C +T FQC C GY + + +C DV+EC P G C
Sbjct: 1606 DIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECE--TPGICGPGTC 1663
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDE--C-----GDQRICDHGDCRNTIGSYRCECK 179
N G + C CPP Y + C D+ C D + CD G+ + C C
Sbjct: 1664 YNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCD-GELLFNMTKKMCCC- 1721
Query: 180 PGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREG 239
Y + + ++C P C + ++ G VD++ECRE
Sbjct: 1722 -SYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLP-------VDIDECREI 1773
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGG 299
VC NG C N VGSFRCEC G+ C D+DEC P C R N C NT G
Sbjct: 1774 PGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGP-VCQR--NAECINTAGS 1830
Query: 300 YECSCGAGWKLVGR-RCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV 358
Y C C G++ +C DR+EC+E+P +C+ G+C + G + C C G++ + +C+
Sbjct: 1831 YRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCL 1890
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
D E D G C + C C+ G F+ +
Sbjct: 1891 D-INECERDACGNGTCRNT----IGSFNCRCNHG-----------------FI------L 1922
Query: 419 GRPNLTQDLDECRV-RPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPR 477
N D+DEC ++C G+C+NT GSF+C+C +GY +APDG +CVD +EC L+PR
Sbjct: 1923 SHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPR 1982
Query: 478 ICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRCTCP 536
C GTC N G Y C C PG++ ++ C D+DEC E C C NT GSF+C CP
Sbjct: 1983 KCAPGTCQNLDGSYRCICPPGYSL-QNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCP 2041
Query: 537 YGYAVAADGVHCRDI--DECVQ--EPRVCPHACENVVGSYICKCP---EGYRRTS--APQ 587
G+++++ G C+D+ C E C C C EG+ P
Sbjct: 2042 EGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPT 2101
Query: 588 DSENACEDI------------NECEEQEDLCSGGVC-----INTDGSFLCDCDAGFEPSE 630
+ + A I + + ++ VC INTDGS+ C+C G+ +
Sbjct: 2102 EPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYTLA- 2160
Query: 631 DGTDCIDRRTGTCYRSLVSGRCE 653
G +C+D + +G C+
Sbjct: 2161 -GNECVDTDECSVGNPCGNGTCK 2182
Score = 318 bits (782), Expect = 4e-86
Identities = 189/546 (34%), Positives = 252/546 (46%), Gaps = 41/546 (7%)
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCR 168
D+DEC P QC+N G++ C CP GY L + EC D DEC C +G C+
Sbjct: 2127 DMDECK--EPDVCKHGQCINTDGSYRCECPFGYTLAGN--ECVDTDECSVGNPCGNGTCK 2182
Query: 169 NTIGSYRCECKPGYTLRENV-CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN 227
N IG + C C+ G+ + C D++EC++ +C C N G+Y C C G+ +
Sbjct: 2183 NVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAF-RCVNTYGSYECKCPVGYVLRED 2241
Query: 228 ND-CVDVNECREGGMVC--RNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHP 284
C D +EC EG C + C+N +G++ C C PGY DG C D +EC P
Sbjct: 2242 RRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGI 2301
Query: 285 CGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDE--C--KELPYVCA-GGECRNFN 337
C N C NT G Y C C G+ + C+D E C + L +C G RN
Sbjct: 2302 CE---NGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPV 2358
Query: 338 GGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGR 397
C C G + +C + GR + EC
Sbjct: 2359 TKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADI--DECKVIHDVCRNG 2416
Query: 398 YCERCPAPDSAEFMRICQGGMGRPNLTQ----DLDECRVRPDVCVGGRCVNTDGSFRCEC 453
C D + IC+ G P++T DL+EC P C C NT+GS++C C
Sbjct: 2417 ECVN----DRGSYHCICKTGY-TPDITGTSCVDLNECNQAPKPC-NFICKNTEGSYQCSC 2470
Query: 454 PDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDEC 513
P GY+L DG SC D DECA C C NT GG+ C+C PGFTQ +C+D +EC
Sbjct: 2471 PKGYILQEDGRSCKDLDECATKQHNC-QFLCVNTIGGFTCKCPPGFTQH-HTSCIDNNEC 2528
Query: 514 AEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGS 571
C + C NT GSF C C G+++ G C D+DEC R C H C+N++G
Sbjct: 2529 TSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHR-CQHGCQNIIGG 2587
Query: 572 YICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSED 631
Y C CP+GY + N C D NEC +C G C NT GS+ C C AGF+ +
Sbjct: 2588 YRCSCPQGYLQ----HYQWNQCVDENECLSAH-ICGGASCHNTLGSYKCMCPAGFQYEQF 2642
Query: 632 GTDCID 637
C D
Sbjct: 2643 SGGCQD 2648
Score = 317 bits (778), Expect = 1e-85
Identities = 233/764 (30%), Positives = 308/764 (40%), Gaps = 82/764 (10%)
Query: 135 CRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYT---LRENVCRD 191
C CP G ++ PS + C + R + G C + C C+ GY + VC
Sbjct: 100 CTCPSG-QIAPSCGS-RSIQHC-NIRCMNGGSCSDD----HCLCQKGYIGTHCGQPVCES 152
Query: 192 VDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE--GGMVCRNGRCR 249
C C G C+ ++ GP + C+ G+VC C
Sbjct: 153 --GCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKQLCC 210
Query: 250 NTVG---SFRCECAP--------GYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
TVG CE P G+ C+DVDEC +P C + GN C NT G
Sbjct: 211 ATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLC-QGGN--CINTVG 267
Query: 299 GYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
+EC C AG KL V ++C D DEC +P +C GGEC N Y C+CP G+
Sbjct: 268 SFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTR 327
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYC----ERCPAPDSAEFMR 412
C+D R CY GRC P + + +CCC G W E CP + +F +
Sbjct: 328 CIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNK 387
Query: 413 ICQGGM---GRPN-----LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
+C M GRP L V P G + P P L
Sbjct: 388 LCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSRE--PPRVL 445
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
D C L +C NG C T G Y C+C+ GF C+DVDEC E C
Sbjct: 446 PVNVTDYCQLVRYLCQNGRCIPTPGSYRCECNKGFQLDLRGECIDVDEC-EKNPCAGGEC 504
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRT 583
N GS+ C C GY CRDIDEC+Q R+C + C N GS+ C C G+ T
Sbjct: 505 INNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVT 564
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRR---- 639
+D +N CED++EC + ++C G+CIN DGSF C C GF+ + DG C D
Sbjct: 565 ---RDGKN-CEDMDECSIR-NMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECET 619
Query: 640 -----TGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTL-GAAW 693
G C + S RCE G + QC L GA
Sbjct: 620 PGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVT 679
Query: 694 GSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAA 753
SEC C A A + C P +D++ECA
Sbjct: 680 KSEC--CCASTEYAFGEPCQP---CPAQNSAEYQALCSSGPGMTSAG-----SDINECAL 729
Query: 754 IPGLC-------APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ-LCHNTDGSYD 803
P +C G ++C+C GY G+ C D++EC + CD C NT GS+
Sbjct: 730 DPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFV 789
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSC 847
C C G+ D C D+DECE + +C N+ GS+ C C
Sbjct: 790 CTCPKGFIYKPDLKTCEDIDECE-SSPCINGVCKNSPGSFICEC 832
Score = 293 bits (719), Expect = 2e-78
Identities = 194/556 (34%), Positives = 253/556 (45%), Gaps = 73/556 (13%)
Query: 63 NETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRG 122
NE DEC + C GTC + GF+C C+ G+E C D++EC+ + P
Sbjct: 2162 NECVDTDECSV-GNPCGNGTCKNVIGGFECTCEEGFE-PGPMMTCEDINECA--QNPLLC 2217
Query: 123 MAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHG--DCRNTIGSYRCECK 179
+CVN G++EC+CP GY L C+D DEC + + C +C+N IG+Y C C
Sbjct: 2218 AFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICG 2277
Query: 180 PGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNE- 235
PGY R + C D +EC +C NG C N G+Y C C+DGF A PN D C+D E
Sbjct: 2278 PGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREG 2337
Query: 236 -CREGGM--VCRNGRC-RNTVGSFRCECAPGY------------------TLTADGR--- 270
C + +C+ G RN V C C G L GR
Sbjct: 2338 YCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFM 2397
Query: 271 -NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK--LVGRRCVDRDECKELPYV 327
N D+DEC + C R+G C N G Y C C G+ + G CVD +EC + P
Sbjct: 2398 TNGADIDECKVIHDVC-RNGE--CVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKP 2454
Query: 328 CAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPEC 387
C C+N G Y C CP G+ + C D DE A + H + L C
Sbjct: 2455 C-NFICKNTEGSYQCSCPKGYILQEDGRSCKD------LDEC-ATKQHNCQFL------C 2500
Query: 388 CCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDG 447
+ G G C +CP P + C + T D++ C + G C NT G
Sbjct: 2501 VNTIG---GFTC-KCP-PGFTQHHTSC---IDNNECTSDINLCGSK------GICQNTPG 2546
Query: 448 SFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QT 506
SF CEC G+ L G SC D DEC + R C +G C N GGY C C G+ Q
Sbjct: 2547 SFTCECQRGFSLDQTGSSCEDVDECEGNHR-CQHG-CQNIIGGYRCSCPQGYLQHYQWNQ 2604
Query: 507 CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
CVD +EC CHNT GS++C CP G+ C+DI+EC C + C
Sbjct: 2605 CVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCS 2664
Query: 567 NVVGSYICKCPEGYRR 582
N G Y+C CP GY R
Sbjct: 2665 NTEGGYLCGCPPGYFR 2680
Score = 241 bits (590), Expect = 7e-63
Identities = 180/563 (31%), Positives = 247/563 (43%), Gaps = 65/563 (11%)
Query: 34 PCEACPPRGSPAHTALCGEKPGEYINPVTNETK--PI---DECDIMPQLCKPGTCHDTPT 88
P PP P P EY+ P + P+ D C ++ LC+ G C TP
Sbjct: 411 PVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPG 470
Query: 89 GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD 148
++C C+ G++ D C DVDEC + PC G +C+N G++ C+C GY+ T +
Sbjct: 471 SYRCECNKGFQLDLRGE-CIDVDECE--KNPCAG-GECINNQGSYTCQCRAGYQSTLTRT 526
Query: 149 ECEDVDEC-GDQRICDHGDCRNTIGSYRCECKPGY--TLRENVCRDVDECSRPRPVCRNG 205
EC D+DEC + RIC++G C NT GS+ C C G+ T C D+DECS R +C NG
Sbjct: 527 ECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECS-IRNMCLNG 585
Query: 206 TCENLPGAYLCHCDDGFK-AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYT 264
C N G++ C C GF+ A C D+NEC G +C NGRC NT GS+RCEC PG
Sbjct: 586 MCINEDGSFKCICKPGFQLASDGRYCKDINECETPG-ICMNGRCVNTDGSYRCECFPGLA 644
Query: 265 LTADGRNCRDVDECDELPHPC-GRDGNPSCTNTNGG----YECSCGAGWKLVGRRC--VD 317
+ DGR C D + C G C G EC C + G C
Sbjct: 645 VGLDGRVCVDT----HMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCP 700
Query: 318 RDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER---KELCYDEWEAGRC 374
E +C+ G G + EC +C + R K +C +E
Sbjct: 701 AQNSAEYQALCSSGPGMTSAGSDINECALDPDICPN-GICENLRGTYKCICNSGYEVDST 759
Query: 375 HRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC-QGGMGRPNL--TQDLDECR 431
+ + EC + C P F+ C +G + +P+L +D+DEC
Sbjct: 760 GKN---CVDINECVLNSLLCDNGQCRNTP----GSFVCTCPKGFIYKPDLKTCEDIDECE 812
Query: 432 VRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDAD-----ECALDPR--ICGNGT- 483
P C+ G C N+ GSF CEC L P C++ + +D R I NG
Sbjct: 813 SSP--CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGAT 870
Query: 484 ----CSNTRG---GYECQ-------CSPGFTQGPDQTCVDVDECAEGRASC-TFRCHNTA 528
C ++ G G C C G+++ C D+DEC C C NT
Sbjct: 871 LKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTR 930
Query: 529 GSFRCTCPYGYAVAADGVHCRDI 551
GSF+C CP G + A G C DI
Sbjct: 931 GSFKCQCPSGMTLDATGRICLDI 953
Score = 234 bits (572), Expect = 1e-60
Identities = 154/483 (31%), Positives = 212/483 (43%), Gaps = 46/483 (9%)
Query: 193 DECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTV 252
D C R +C+NG C PG+Y C C+ GF+ +C+DV+EC + C G C N
Sbjct: 451 DYCQLVRYLCQNGRCIPTPGSYRCECNKGFQLDLRGECIDVDECEKN--PCAGGECINNQ 508
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV- 311
GS+ C+C GY T CRD+DEC + C N C NT+G + C C AG+ +
Sbjct: 509 GSYTCQCRAGYQSTLTRTECRDIDECLQNGRIC---NNGRCINTDGSFHCVCNAGFHVTR 565
Query: 312 -GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWE 370
G+ C D DEC + +C G C N +G + C C G++ C D +E E
Sbjct: 566 DGKNCEDMDEC-SIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKD------INECE 618
Query: 371 A-GRCHRARPLQL-ARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLD 428
G C R + C C G A G C C GG R + L
Sbjct: 619 TPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCV---DTHMRSTCYGGYKRGQCIKPLF 675
Query: 429 ECRVRPDVCVGGRCVNTDGSF--RCE-CP-----DGYVLAPDGLSCV----DADECALDP 476
+ + C C +T+ +F C+ CP + L G D +ECALDP
Sbjct: 676 GAVTKSECC----CASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDP 731
Query: 477 RICGNGTCSNTRGGYECQCSPGF-TQGPDQTCVDVDECAEGRASC-TFRCHNTAGSFRCT 534
IC NG C N RG Y+C C+ G+ + CVD++EC C +C NT GSF CT
Sbjct: 732 DICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCT 791
Query: 535 CPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACE 594
CP G+ D C DIDEC P + C+N GS+IC+C S ++ C
Sbjct: 792 CPKGFIYKPDLKTCEDIDECESSPCI-NGVCKNSPGSFICECSS----ESTLDPTKTICI 846
Query: 595 DINECEEQEDLCSGGVCINTDGSFL---CDCDAGFEPSEDGTDC-IDRRTGTCYRSLVSG 650
+ + + + G IN +G+ L C G T C +D G Y +
Sbjct: 847 ETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGT 906
Query: 651 RCE 653
+CE
Sbjct: 907 QCE 909
Score = 216 bits (528), Expect = 2e-55
Identities = 149/478 (31%), Positives = 198/478 (41%), Gaps = 71/478 (14%)
Query: 66 KPIDECDIMPQLC--KPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGM 123
K DEC+ C K C + + C C GY+ C D +EC C
Sbjct: 2246 KDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICEN- 2304
Query: 124 AQCVNLPGAFECRCPPGYRLTPSLDECEDVDE--CGD---QRICDHGDC-RNTIGSYRCE 177
+C+N G++ C C G+ +P+ DEC D E C Q +C G RN + C
Sbjct: 2305 GRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECC 2364
Query: 178 CK--------------PGYTLRENVC----------RDVDECSRPRPVCRNGTCENLPGA 213
C G + +C D+DEC VCRNG C N G+
Sbjct: 2365 CDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGS 2424
Query: 214 YLCHCDDGFKAG-PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNC 272
Y C C G+ CVD+NEC + C N C+NT GS++C C GY L DGR+C
Sbjct: 2425 YHCICKTGYTPDITGTSCVDLNECNQAPKPC-NFICKNTEGSYQCSCPKGYILQEDGRSC 2483
Query: 273 RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAG-G 331
+D+DEC H C C NT GG+ C C G+ C+D +EC +C G
Sbjct: 2484 KDLDECATKQHNC----QFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKG 2539
Query: 332 ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAG-RCHRARPLQLARPECCCS 390
C+N G + CEC G+ D+T + C D DE E RC + C C
Sbjct: 2540 ICQNTPGSFTCECQRGFSLDQTGSSCED------VDECEGNHRCQHGCQNIIGGYRCSCP 2593
Query: 391 EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFR 450
+G +C D +EC + +C G C NT GS++
Sbjct: 2594 QGYLQHYQWNQCV----------------------DENEC-LSAHICGGASCHNTLGSYK 2630
Query: 451 CECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV 508
C CP G+ C D +EC C G CSNT GGY C C PG+ + CV
Sbjct: 2631 CMCPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGCPPGYFRIGQGHCV 2687
Score = 140 bits (339), Expect = 2e-32
Identities = 113/358 (31%), Positives = 146/358 (40%), Gaps = 39/358 (10%)
Query: 210 LPGAYLCH-CDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGS-FRCECAPGYTLTA 267
L +Y H D +AG + R GG + N GS + C PG+
Sbjct: 16 LLASYTSHGADANLEAGNVKETRASRAKRRGGGGHDALKGPNVCGSRYNAYCCPGWKTLP 75
Query: 268 DGRNCRDVDECDELPHPCGRDG---NPS-CTNTNGGYECSCGA-GWKLVGRRCVDRDECK 322
G C V C H CG DG P+ CT +G SCG+ + RC++ C
Sbjct: 76 GGNQCI-VPICR---HSCG-DGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCS 130
Query: 323 ELPYVCAGGECRNFNGGYVCE--CPAGWRF--DKTAAVCVDERKELCYDEWEAGRCHRAR 378
+ +C G G VCE C G R A C ++ G C
Sbjct: 131 DDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVI 190
Query: 379 PLQLARPE----------CCCSEGAAWGRYCERCPAPDSAEFMRICQGGMG---RPNLTQ 425
Q+ + + CC + G AWG CE CPA C+ G R Q
Sbjct: 191 SNQMCQGQLSGIVCTKQLCCATVGRAWGHPCEMCPAQPHP-----CRRGFIPNIRTGACQ 245
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
D+DEC+ P +C GG C+NT GSF C+CP G+ L C D DEC+ P IC G C+
Sbjct: 246 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECT 305
Query: 486 NTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFRCHN----TAGSFRCTCPYG 538
NT Y C+C PGF PD T C+DV A RC N + +C C G
Sbjct: 306 NTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 363
Score = 128 bits (310), Expect = 6e-29
Identities = 99/330 (30%), Positives = 133/330 (40%), Gaps = 53/330 (16%)
Query: 411 MRICQGGMGRPNL-TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
M C G P+ ++ + C +R C+ G + D C C GY+ G ++
Sbjct: 99 MCTCPSGQIAPSCGSRSIQHCNIR---CMNGGSCSDD---HCLCQKGYIGTHCGQPVCES 152
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS---CTFR-CH 525
C R C+ T G QC + GP T + C +G+ S CT + C
Sbjct: 153 G-CLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMC-QGQLSGIVCTKQLCC 210
Query: 526 NTAG---SFRCT--------CPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYI 573
T G C C G+ C+D+DEC P +C C N VGS+
Sbjct: 211 ATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFE 270
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGT 633
CKCP G++ Q CEDI+EC +C GG C NT S+ C C GF S DGT
Sbjct: 271 CKCPAGHKLNEVSQK----CEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGT 326
Query: 634 DCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAW 693
CID R G CY +L +GRC + +TK QCCC G W
Sbjct: 327 RCIDVRPGYCYTALTNGRCSNQLPQS--------------------ITKMQCCCDAGRCW 366
Query: 694 GSEC----ELCPAPGSPARLDLCTAVNLTP 719
E+CP + LC+ + P
Sbjct: 367 SPGVTVAPEMCPIRATEDFNKLCSVPMVIP 396
Score = 126 bits (305), Expect = 3e-28
Identities = 77/245 (31%), Positives = 102/245 (41%), Gaps = 19/245 (7%)
Query: 2 EWNEEDQSCAGAVGVPQTKYLCCCSVGHAW---GAPCEACPPRGSPAHTA--LCGEKPGE 56
E N+ + C + Y C C G+ G C+ + H LC G
Sbjct: 2447 ECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGG 2506
Query: 57 YINP-----VTNETKPID--ECDIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLCR 108
+ + T ID EC LC G C +TP F C C G+ D T C
Sbjct: 2507 FTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE 2566
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCR 168
DVDEC G C+ C N+ G + C CP GY ++C D +EC IC C
Sbjct: 2567 DVDECE-GNHRCQH--GCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCH 2623
Query: 169 NTIGSYRCECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGP 226
NT+GSY+C C G+ + C+D++EC + C G C N G YLC C G+
Sbjct: 2624 NTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGCPPGYFRIG 2682
Query: 227 NNDCV 231
CV
Sbjct: 2683 QGHCV 2687
Score = 120 bits (290), Expect = 2e-26
Identities = 66/194 (34%), Positives = 93/194 (47%), Gaps = 19/194 (9%)
Query: 7 DQSCAGAV-GVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNET 65
+Q C G + G+ TK LCC +VG AWG PCE CP + P + G N T
Sbjct: 192 NQMCQGQLSGIVCTKQLCCATVGRAWGHPCEMCPAQPHPC-------RRGFIPNIRTGAC 244
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ 125
+ +DEC +P LC+ G C +T F+C C G++ + S C D+DECS C G +
Sbjct: 245 QDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEG-GE 303
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRN----TIGSYRCEC--- 178
C N ++ C+CPPG+ +P C DV +G C N +I +C C
Sbjct: 304 CTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 363
Query: 179 ---KPGYTLRENVC 189
PG T+ +C
Sbjct: 364 RCWSPGVTVAPEMC 377
Score = 97.5 bits (232), Expect = 2e-19
Identities = 46/124 (37%), Positives = 65/124 (52%), Gaps = 12/124 (9%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYRPAGEV--CADVDECAVRPPPC-DQLCH 796
D+DEC P +C PG +RC+C G+ + ++ C DV+EC + P C C
Sbjct: 1238 DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCE 1297
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKR 854
NT GS+ C C GY + C D++ECE H C +C+NT GS++CSC G+
Sbjct: 1298 NTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGD 1357
Query: 855 GDAC 858
G C
Sbjct: 1358 GIKC 1361
Score = 97.1 bits (231), Expect = 2e-19
Identities = 48/122 (39%), Positives = 61/122 (50%), Gaps = 12/122 (9%)
Query: 747 DVDECAAIPGLCA-------PGRFRCVCGPGYRPAGEV---CADVDECAVRPPPC-DQLC 795
D+DEC P LC PG F C C GY + C D+DEC P C +C
Sbjct: 1070 DIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVC 1129
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKR 854
HNT+GSY C C G++L + + C D++ECE H C C N G Y+C+C GY
Sbjct: 1130 HNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHST 1189
Query: 855 GD 856
D
Sbjct: 1190 PD 1191
Score = 96.3 bits (229), Expect = 4e-19
Identities = 47/113 (41%), Positives = 57/113 (50%), Gaps = 9/113 (7%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNT 798
D+DECA C G F C C PG+ C D +EC C +C NT
Sbjct: 2485 DLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNT 2544
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
GS+ C C+ G+ LD+ G++C DVDECE H CQ C N G Y CSC GY
Sbjct: 2545 PGSFTCECQRGFSLDQTGSSCEDVDECE-GNHRCQHGCQNIIGGYRCSCPQGY 2596
Score = 94.3 bits (224), Expect = 2e-18
Identities = 45/115 (39%), Positives = 58/115 (50%), Gaps = 10/115 (8%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ-LCH 796
D+DEC P LC G +RC C PG++ P C D++EC + C C
Sbjct: 1113 DIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCV 1172
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
N G Y C C GY D C D+DEC C+ C+N+EGSYECSC+ G+
Sbjct: 1173 NLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGF 1227
Score = 91.5 bits (217), Expect = 1e-17
Identities = 44/118 (37%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 747 DVDECAAIP---GLCA--PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQ-LCHNT 798
DVDEC P G C G + C C GY+ C D+DEC C+ C NT
Sbjct: 490 DVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINT 549
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
DGS+ C+C G+ + DG NC D+DEC +C N +GS++C C+ G++ D
Sbjct: 550 DGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASD 607
Score = 90.2 bits (214), Expect = 3e-17
Identities = 49/125 (39%), Positives = 62/125 (49%), Gaps = 15/125 (12%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYR-PAGEV-CADVDECAVRPPPCDQ--LC 795
DV+EC P +C G F C C GY G+ C D++EC + C + +C
Sbjct: 1280 DVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVC 1339
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEK 853
NT GS+ C C G+ DG C D+DEC TH C Q C NT GSY C C++GY
Sbjct: 1340 TNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTG 1397
Query: 854 RGDAC 858
G C
Sbjct: 1398 DGFTC 1402
Score = 85.8 bits (203), Expect = 6e-16
Identities = 38/94 (40%), Positives = 55/94 (58%), Gaps = 5/94 (5%)
Query: 765 CVCGPGYRPAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
C GPG AG +D++ECA+ P C +C N G+Y C+C +GYE+D G NC D++
Sbjct: 711 CSSGPGMTSAG---SDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDIN 767
Query: 824 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
EC ++ C C NT GS+ C+C G+ + D
Sbjct: 768 ECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPD 801
Score = 84.2 bits (199), Expect = 2e-15
Identities = 41/100 (41%), Positives = 52/100 (52%), Gaps = 5/100 (5%)
Query: 760 PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG +RC C G++ GE C DVDEC P + C N GSY C CR GY+
Sbjct: 469 PGSYRCECNKGFQLDLRGE-CIDVDECEKNPCAGGE-CINNQGSYTCQCRAGYQSTLTRT 526
Query: 818 NCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
CRD+DEC ++ C C NT+GS+ C C G+ D
Sbjct: 527 ECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRD 566
Score = 83.0 bits (196), Expect = 4e-15
Identities = 39/102 (38%), Positives = 51/102 (50%), Gaps = 3/102 (2%)
Query: 761 GRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
G +RC C GY + C D +EC CHNT GSY C+C G++ ++
Sbjct: 2586 GGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGG 2645
Query: 819 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
C+D++EC C CSNTEG Y C C GY + G CV
Sbjct: 2646 CQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCV 2687
Score = 71.7 bits (168), Expect = 1e-11
Identities = 41/112 (36%), Positives = 51/112 (45%), Gaps = 8/112 (7%)
Query: 746 ADVDECAAIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTDGS 801
+D++ C + G+C PG F C C G+ G C DVDEC C C N G
Sbjct: 2530 SDINLCGS-KGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHR-CQHGCQNIIGG 2587
Query: 802 YDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYE 852
Y C C GY C D +EC H C C NT GSY+C C G++
Sbjct: 2588 YRCSCPQGYLQHYQWNQCVDENEC-LSAHICGGASCHNTLGSYKCMCPAGFQ 2638
Score = 70.1 bits (164), Expect = 3e-11
Identities = 32/76 (42%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Query: 778 CADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ-QI 835
C DVDEC P C C NT GS++C C G++L+E C D+DEC C+
Sbjct: 244 CQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGE 303
Query: 836 CSNTEGSYECSCEDGY 851
C+NT SY C C G+
Sbjct: 304 CTNTVSSYFCKCPPGF 319
Score = 69.7 bits (163), Expect = 4e-11
Identities = 43/118 (36%), Positives = 53/118 (44%), Gaps = 14/118 (11%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ-LCH 796
DVDEC AIPGLC G F C C G++ + C D+DEC+ P C+ C
Sbjct: 246 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECT 305
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSN----TEGSYECSCEDG 850
NT SY C C G+ DG C DV T CSN + +C C+ G
Sbjct: 306 NTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 363
Score = 50.0 bits (114), Expect = 4e-05
Identities = 38/155 (24%), Positives = 52/155 (33%), Gaps = 12/155 (7%)
Query: 560 VCPHACENVVGSY--ICKCPEGYRRTSAPQDSENACE----DINECEEQEDLCSGGVCIN 613
+C H+C + S +C CP G S S C + C + LC G
Sbjct: 84 ICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGT 143
Query: 614 TDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXX 673
G +C+ +G C+ C +CE +
Sbjct: 144 HCGQPVCESGC-----LNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQ 198
Query: 674 XXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPAR 708
TK CC T+G AWG CE+CPA P R
Sbjct: 199 LSGIV-CTKQLCCATVGRAWGHPCEMCPAQPHPCR 232
Score = 43.6 bits (98), Expect = 0.003
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE 852
CR G+ + C+DVDEC+ CQ C NT GS+EC C G++
Sbjct: 231 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHK 278
Score = 39.1 bits (87), Expect = 0.066
Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 3/73 (4%)
Query: 790 PCDQLCHNTDGSYDCLCR--TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECS 846
PC+ Y LC G+ + D+DEC+ CQ C NT GS++C
Sbjct: 1573 PCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCR 1632
Query: 847 CEDGYEKRGDACV 859
C GY D V
Sbjct: 1633 CPTGYYLNEDTRV 1645
>AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital
contractural arachnodactyly) variant protein.
Length = 1976
Score = 630 bits (1555), Expect = e-180
Identities = 288/719 (40%), Positives = 397/719 (55%), Gaps = 44/719 (6%)
Query: 9 SCAGAVGVPQTKYLCCCS--VGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETK 66
+C + TK +CCC+ VG AW PCE CP G+ +CG PG + T +
Sbjct: 812 TCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAV 871
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
IDEC +P +C G C + F+C C G+ +++ +C D+DECS G C+ A C
Sbjct: 872 DIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADC 931
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTLR 185
+N PG++ C C G++L+P+ C D +EC + +C HG C + GSY+C C G+
Sbjct: 932 INSPGSYRCECAAGFKLSPN-GACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKAS 990
Query: 186 EN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE-GGMV 242
++ +C DVDEC R P C NGTC+N G+Y C C GF+ NNDC+D++EC G V
Sbjct: 991 QDQTMCMDVDECER-HP-CGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQV 1048
Query: 243 CRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC 302
CRNGRC N +GSF+C C GY LT DG+NC D +EC LP C +C N G + C
Sbjct: 1049 CRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPG---TCQNLEGSFRC 1105
Query: 303 SCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
C G+++ C+D +EC E P +C G C N GG+ C CP G+ C D R+
Sbjct: 1106 ICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQ 1165
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMRICQGGMGR 420
C+ +E G+C + + +CCCS+ G WG CE CP D F +C G G
Sbjct: 1166 SFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGT 1225
Query: 421 -PNL---TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDP 476
P+L +D++EC P +C G+C+NTDGSFRCECP GY L G+ CVD DEC++
Sbjct: 1226 VPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIG- 1284
Query: 477 RICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCP 536
CGNGTC+N G +EC C+ GF GP C D++ECA+ C FRC NT GS+ CTCP
Sbjct: 1285 NPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCP 1344
Query: 537 YGYAVAADGVHCRDIDECVQEPRVCPH---ACENVVGSYICKCPEGYRRTSAPQDSENAC 593
GYA+ D C+D+DEC + C C+N++G+++C CP G R D E C
Sbjct: 1345 IGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARR---PDGE-GC 1400
Query: 594 EDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCE 653
D NEC + +C G C+N GS+ C+C+ GF+ S GT+C+D R G C+ ++ C+
Sbjct: 1401 VDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQ 1460
Query: 654 PEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLC 712
VTK++CCC G WG +CELCP PG+ +C
Sbjct: 1461 ------------------MASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKIC 1501
Score = 451 bits (1112), Expect = e-126
Identities = 294/845 (34%), Positives = 372/845 (44%), Gaps = 131/845 (15%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC+ P LC+ GTC +T FQC C G+E + C D++ECS CR +CV
Sbjct: 223 IDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRN-GKCV 281
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
N+ G ++C C PGY+ TP C D+DEC C N+ GSY C C GY L +
Sbjct: 282 NMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPD 341
Query: 188 --VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCR 244
C D+DEC +C G C N+PG Y C C DGF A + C+DVNEC +C
Sbjct: 342 GRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICM 401
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
G C NT GSF C C GY++ C DVDEC+ H C D + SC N G ++CSC
Sbjct: 402 FGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNC--DMHASCLNIPGSFKCSC 459
Query: 305 GAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
GW G +C+D DEC + C+ +C N G Y C C G+ D VDE E
Sbjct: 460 REGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAE 519
Query: 364 LCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNL 423
+ E G+C C C G PA DS R C
Sbjct: 520 -NINLCENGQCLNVP----GAYRCECEMGFT--------PASDS----RSC--------- 553
Query: 424 TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT 483
QD+DEC + ++CV G C N G F C C DGY L G +C D DECA DP C NG
Sbjct: 554 -QDIDECSFQ-NICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECA-DPINCVNGL 610
Query: 484 CSNTRGGYECQCSPGFTQGPDQT-CVD--VDEC-------AEGRASCTFRCHNTAGSFRC 533
C NT G YEC C P F P CVD V C +G SC C
Sbjct: 611 CVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSC 670
Query: 534 TCPYG------------------YAVAADGVHCRD-----IDECVQEPRVCPHACE---- 566
C G Y + G R I E + E + P C+
Sbjct: 671 CCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNC 730
Query: 567 -NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
N GS+ C+CP+GY + + CEDI+EC +C G C NT G++ C C
Sbjct: 731 INTFGSFQCECPQGYYLS----EDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPE 786
Query: 626 FEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQC 685
+ G +C+D R CYRS CE E +VTK C
Sbjct: 787 YMQVNGGHNCMDMRKSFCYRSYNGTTCENELPF--------------------NVTKRMC 826
Query: 686 CCT--LGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLD 743
CCT +G AW CE CP PG+ D T P
Sbjct: 827 CCTYNVGKAWNKPCEPCPTPGT---ADFKTICGNIPGFTFDIHTGKA------------- 870
Query: 744 VFADVDECAAIPGLCAP-------GRFRCVCGPG--YRPAGEVCADVDECAVRPPPCDQL 794
D+DEC IPG+CA G FRC C G Y VC D+DEC+ C +
Sbjct: 871 --VDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRN 928
Query: 795 --CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGY 851
C N+ GSY C C G++L +GA C D +EC + C +C + +GSY+C C +G+
Sbjct: 929 ADCINSPGSYRCECAAGFKLSPNGA-CVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGF 987
Query: 852 EKRGD 856
+ D
Sbjct: 988 KASQD 992
Score = 443 bits (1091), Expect = e-123
Identities = 235/634 (37%), Positives = 321/634 (50%), Gaps = 61/634 (9%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDE-----------CSWG 116
I+ECD P +C G+C +TP GFQC C G+ + C D + CS
Sbjct: 1121 INECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVP 1180
Query: 117 RP--PCRGMAQCVNLPG----------------AFECRCPPGYRLTPSL-DECEDVDECG 157
+ + C +PG AF+ CP G+ PSL D EDV+EC
Sbjct: 1181 KAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECL 1240
Query: 158 DQR-ICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAY 214
+ IC +G C NT GS+RCEC GY L C D DECS P C NGTC N+ G++
Sbjct: 1241 ESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP-CGNGTCTNVIGSF 1299
Query: 215 LCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRD 274
C+C++GF+ GP +C D+NEC + ++C RC NT GS+ C C GY L D + C+D
Sbjct: 1300 ECNCNEGFEPGPMMNCEDINECAQNPLLCAF-RCMNTFGSYECTCPIGYALREDQKMCKD 1358
Query: 275 VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW--KLVGRRCVDRDECKELPYVCAGGE 332
+DEC E H C G C N G + C C G + G CVD +EC+ P +C G
Sbjct: 1359 LDECAEGLHDCESRGM-MCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGR 1417
Query: 333 CRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQ--LARPECCCS 390
C N G Y CEC G++ + C+D R+ LC+ E C A + + + ECCC
Sbjct: 1418 CVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCD 1477
Query: 391 EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFR 450
G WG CE CP P +A++ +IC G G +D+DEC+V P++C G+C+NT GSFR
Sbjct: 1478 GGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFR 1537
Query: 451 CECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVD 509
C C GY G SC+D DEC+ P+ C N C NT G Y+C C G+ Q +TC D
Sbjct: 1538 CFCKVGYTTDISGTSCIDLDECSQSPKPC-NYICKNTEGSYQCSCPRGYVLQEDGKTCKD 1596
Query: 510 VDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC--PHACEN 567
+DEC + +C F C NT G F C CP G+ C D +EC +P +C C+N
Sbjct: 1597 LDECQTKQHNCQFLCVNTLGGFTCKCPPGF--TQHHTACIDNNECGSQPSLCGAKGICQN 1654
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
GS+ C+C G+ + + CED++EC+ C G C N G + C C G+
Sbjct: 1655 TPGSFSCECQRGFSLDATGLN----CEDVDECDGNH-RCQHG-CQNILGGYRCGCPQGYI 1708
Query: 628 PSEDGTDCIDRR---------TGTCYRSLVSGRC 652
C+D + +CY +L S +C
Sbjct: 1709 QHYQWNQCVDENECSNPNACGSASCYNTLGSYKC 1742
Score = 438 bits (1078), Expect = e-122
Identities = 258/766 (33%), Positives = 355/766 (46%), Gaps = 99/766 (12%)
Query: 108 RDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG-DQRICDHGD 166
+D++EC C +C N G+F+CRC G+ L C D+DEC +C G
Sbjct: 136 KDINECKAFPGMCT-YGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGI 194
Query: 167 CRNTIGSYRCECKPGYT---LRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK 223
C NT GS+ CEC GY + C D+DEC R +CR GTC N G++ C C G +
Sbjct: 195 CVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHE 254
Query: 224 AGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELP 282
P+ DCVD+NEC +CRNG+C N +G+++C C PGY T D + C D+DEC +
Sbjct: 255 LSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMN 314
Query: 283 HPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGY 340
C + CTN+ G YECSC G+ L+ GR C D DEC+ P +C GG+C N G Y
Sbjct: 315 GGC----DTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEY 370
Query: 341 VCECPAGWRFDKTAAVCVDERK-ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYC 399
C C G+ C+D + +L + G C + + C C G +
Sbjct: 371 RCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFI----CHCQLGYS----- 421
Query: 400 ERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYV 458
+ +G G D+DEC + C + C+N GSF+C C +G++
Sbjct: 422 -------------VKKGTTG----CTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWI 464
Query: 459 LAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGR 517
+G+ C+D DEC+ C N C NT G Y C CS GFT G TC DVDECAE
Sbjct: 465 --GNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFT-GDGFTCSDVDECAENI 521
Query: 518 ASC-TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKC 576
C +C N G++RC C G+ A+D C+DIDEC + C N+ G + C C
Sbjct: 522 NLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCIC 581
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCI 636
+GY + C DI+EC + + C G+C+NT G + C+C F+ + G C+
Sbjct: 582 DDGYEL----DRTGGNCTDIDECADPIN-CVNGLCVNTPGRYECNCPPDFQLNPTGVGCV 636
Query: 637 DRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSE 696
D R G CY L G P V+++ CCC+LG AWG+
Sbjct: 637 DNRVGNCY--LKFG---PRGDGSLSCNTEIGVG----------VSRSSCCCSLGKAWGNP 681
Query: 697 CELCPAPGSPARLDLCT-AVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP 755
CE CP S LC P + D+DEC +P
Sbjct: 682 CETCPPVNSTEYYTLCPGGEGFRPNPITI-------------------ILEDIDECQELP 722
Query: 756 GLCAPGR-------FRCVCGPGYRPAGE--VCADVDECAVRPPPCDQ-LCHNTDGSYDCL 805
GLC G F+C C GY + + +C D+DEC P C C+NT G+Y C+
Sbjct: 723 GLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCI 782
Query: 806 CRTGYELDEDGANCRDVDE--CERDTH--TCQQICSNTEGSYECSC 847
C Y G NC D+ + C R + TC+ C C
Sbjct: 783 CPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCC 828
Score = 394 bits (971), Expect = e-109
Identities = 227/635 (35%), Positives = 299/635 (47%), Gaps = 54/635 (8%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C G + P IDEC+ P +C G C + P ++C C G+ C D
Sbjct: 330 CSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCID 389
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG-DQRICD-HGDC 167
V+EC C +C N G+F C C GY + C DVDEC CD H C
Sbjct: 390 VNECDLNSNICM-FGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASC 448
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGP 226
N GS++C C+ G+ C D+DECS C N C N PG+Y C C +GF G
Sbjct: 449 LNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGF-TGD 507
Query: 227 NNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C DV+EC E +C NG+C N G++RCEC G+T +D R+C+D+DEC + C
Sbjct: 508 GFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECS-FQNICV 566
Query: 287 RDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
+C N G + C C G++L G C D DEC + P C G C N G Y C C
Sbjct: 567 FG---TCNNLPGMFHCICDDGYELDRTGGNCTDIDECAD-PINCVNGLCVNTPGRYECNC 622
Query: 345 PAGWRFDKTAAVCVDERKELCYDEWEAG-----RCHRARPLQLARPECCCSEGAAWGRYC 399
P ++ + T CVD R CY ++ C+ + ++R CCCS G AWG C
Sbjct: 623 PPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPC 682
Query: 400 ERCPAPDSAEFMRICQGGMG-RPN----LTQDLDECRVRPDVCVGGRCVNTDGSFRCECP 454
E CP +S E+ +C GG G RPN + +D+DEC+ P +C GG C+NT GSF+CECP
Sbjct: 683 ETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECP 742
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ-GPDQTCVDVDEC 513
GY L+ D C D DEC P +CG GTC NT G Y C C P + Q C+D+ +
Sbjct: 743 QGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKS 802
Query: 514 AEGRASCTFRCHN----TAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVV 569
R+ C N C C Y A + C EP P +
Sbjct: 803 FCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWN-------KPC--EPCPTPGTAD--- 850
Query: 570 GSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPS 629
IC G+ DI+EC+E +C+ GVCIN GSF C+C GF +
Sbjct: 851 FKTICGNIPGF----TFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYN 906
Query: 630 ------EDGTDC-----IDRRTGTCYRSLVSGRCE 653
ED +C + +R C S S RCE
Sbjct: 907 DLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCE 941
Score = 392 bits (965), Expect = e-108
Identities = 275/841 (32%), Positives = 370/841 (43%), Gaps = 137/841 (16%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD--VDECSWGRPPCRGMAQ 125
IDEC P C G C +TP ++C C ++ + T C D V C P RG
Sbjct: 597 IDEC-ADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGP-RG--- 651
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
G+ C G ++ S C G+ C+ N+ Y C G R
Sbjct: 652 ----DGSLSCNTEIGVGVSRSSCCCSLGKAWGNP--CETCPPVNSTEYYTL-CPGGEGFR 704
Query: 186 EN----VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGG 240
N + D+DEC +C+ G C N G++ C C G+ + C D++EC
Sbjct: 705 PNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHP 764
Query: 241 MVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE-----------CD-ELP------ 282
VC G C NT+G++ C C P Y G NC D+ + C+ ELP
Sbjct: 765 GVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKR 824
Query: 283 -----HPCGRDGNPSC----TNTNGGYECSCGA----GWKLVGRRCVDRDECKELPYVCA 329
+ G+ N C T ++ CG + + + VD DECKE+P +CA
Sbjct: 825 MCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICA 884
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
G C N G + CECP G+ ++ VC D DE C L +C
Sbjct: 885 NGVCINQIGSFRCECPTGFSYNDLLLVCED------IDE-----CSNGDNLCQRNADCIN 933
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
S G+ RC + A ++ G D +EC P+VC G CV+ GS+
Sbjct: 934 SPGSY------RC---ECAAGFKLSPNGA-----CVDRNECLEIPNVCSHGLCVDLQGSY 979
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVD 509
+C C +G+ + D C+D DEC P CGNGTC NT G Y C C PGF + C+D
Sbjct: 980 QCICHNGFKASQDQTMCMDVDECERHP--CGNGTCKNTVGSYNCLCYPGFELTHNNDCLD 1037
Query: 510 VDECAE--GRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC-PHACE 566
+DEC+ G+ RC N GSF+C C GY + DG +C D +ECV P C P C+
Sbjct: 1038 IDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQ 1097
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
N+ GS+ C CP GY SEN C DINEC+E ++C G C NT G F C C GF
Sbjct: 1098 NLEGSFRCICPPGYE-----VKSEN-CIDINECDEDPNICLFGSCTNTPGGFQCLCPPGF 1151
Query: 627 EPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCC 686
S++G C D R C+ + +G+C + TKA+CC
Sbjct: 1152 VLSDNGRRCFDTRQSFCFTNFENGKCSVPKAF--------------------NTTKAKCC 1191
Query: 687 CTL--GAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDV 744
C+ G WG CELCP A DLC + T D
Sbjct: 1192 CSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLH-------------------DT 1232
Query: 745 FADVDECAAIPGLCAPGR-------FRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLC 795
DV+EC PG+C+ G+ FRC C GY G C D DEC++ P + C
Sbjct: 1233 REDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTC 1292
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
N GS++C C G+E NC D++EC ++ C C NT GSYEC+C GY R
Sbjct: 1293 TNVIGSFECNCNEGFE-PGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALRE 1351
Query: 856 D 856
D
Sbjct: 1352 D 1352
Score = 390 bits (961), Expect = e-108
Identities = 217/597 (36%), Positives = 292/597 (48%), Gaps = 54/597 (9%)
Query: 1 MEWNEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
++W+E++ C V CCC+VG AWG CE CP G+ + LC G + N
Sbjct: 69 LKWDEDE--CIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAG-FANR 125
Query: 61 ---VTNET--KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSW 115
+T K I+EC P +C G C +T F+C C+ G+ D C D+DEC
Sbjct: 126 GDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRI 185
Query: 116 GRPPCRGMAQCVNLPGAFECRCPPGYRL-TPSLDECEDVDEC-GDQRICDHGDCRNTIGS 173
C G CVN PG+FEC C GY + C D+DEC + +C G C NT GS
Sbjct: 186 SPDLC-GSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGS 244
Query: 174 YRCECKPGYTL---RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND- 229
++C+C G+ L RE+ C D++ECS +CRNG C N+ G Y C C+ G++A P+
Sbjct: 245 FQCDCPLGHELSPSRED-CVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQG 303
Query: 230 CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDG 289
C D++EC C + +C N+ GS+ C C+ GY L DGR+C D+DEC+ P C DG
Sbjct: 304 CTDIDECMIMNGGC-DTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDIC--DG 360
Query: 290 NPSCTNTNGGYECSCGAGW--KLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
CTN G Y C C G+ + + C+D +EC +C GEC N G ++C C G
Sbjct: 361 G-QCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLG 419
Query: 348 WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS 407
+ K C D DE E G H C A+ C P
Sbjct: 420 YSVKKGTTGCTD------VDECEIG-AHN------------CDMHAS----CLNIP---- 452
Query: 408 AEFMRIC-QGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLS 465
F C +G +G DLDEC C + +CVNT GS+RC C +G+ DG +
Sbjct: 453 GSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGF--TGDGFT 510
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRC 524
C D DECA + +C NG C N G Y C+C GFT D ++C D+DEC+ C
Sbjct: 511 CSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTC 570
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
+N G F C C GY + G +C DIDEC C N G Y C CP ++
Sbjct: 571 NNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQ 627
Score = 362 bits (891), Expect = 3e-99
Identities = 223/663 (33%), Positives = 301/663 (45%), Gaps = 75/663 (11%)
Query: 9 SCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPI 68
SC +GV ++ CCCS+G AWG PCE CPP S + LC G NP+T + I
Sbjct: 656 SCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDI 715
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC +P LC+ G C +T FQC C GY + +C D+DEC + P G C N
Sbjct: 716 DECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDEC-FAHPGVCGPGTCYN 774
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTI--GSYRCECKPGYTLRE 186
G + C CPP Y C D+ + R + C N + + C Y + +
Sbjct: 775 TLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGK 834
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
+ + C P C N+PG + G KA VD++EC+E +C NG
Sbjct: 835 AWNKPCEPCPTPGTADFKTICGNIPG-FTFDIHTG-KA------VDIDECKEIPGICANG 886
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
C N +GSFRCEC G++ C D+DEC + C R N C N+ G Y C C A
Sbjct: 887 VCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQR--NADCINSPGSYRCECAA 944
Query: 307 GWKL-VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
G+KL CVDR+EC E+P VC+ G C + G Y C C G++ + +C+D
Sbjct: 945 GFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMD------ 998
Query: 366 YDEWEAGRCHRAR-PLQLARPECCCSEGAAWGRYCERCPAPDSAEFM-RICQGGMGRPNL 423
DE E C + C C G + + + F ++C+ G
Sbjct: 999 VDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNG------ 1052
Query: 424 TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT 483
RC N GSF+C C +GY L PDG +C+D +EC P C GT
Sbjct: 1053 -----------------RCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGT 1095
Query: 484 CSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYAVA 542
C N G + C C PG+ + + C+D++EC E C F C NT G F+C CP G+ ++
Sbjct: 1096 CQNLEGSFRCICPPGY-EVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLS 1154
Query: 543 ADGVHCRDIDE--CVQ--EPRVC--PHACENVVGSYIC-KCP-EGYRRTS--APQDSENA 592
+G C D + C E C P A C K P EG+ P+D E A
Sbjct: 1155 DNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVA 1214
Query: 593 ----C--------------EDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTD 634
C ED+NEC E +CS G CINTDGSF C+C G+ G
Sbjct: 1215 FQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVR 1274
Query: 635 CID 637
C+D
Sbjct: 1275 CVD 1277
Score = 360 bits (886), Expect = 1e-98
Identities = 220/645 (34%), Positives = 296/645 (45%), Gaps = 48/645 (7%)
Query: 4 NEEDQSCAGAVGVPQTKYLCCCSV--GHAWGAPCEACPPRGSPAHTALCGEKPGEYINPV 61
N E+ C+ TK CCCS G WG PCE CP A LC G P
Sbjct: 1171 NFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTV--PS 1228
Query: 62 TNETKP-IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
++T+ ++EC P +C G C +T F+C C GY D T C D DECS G P C
Sbjct: 1229 LHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP-C 1287
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
G C N+ G+FEC C G+ P ++ CED++EC + C NT GSY C C
Sbjct: 1288 -GNGTCTNVIGSFECNCNEGFEPGPMMN-CEDINECAQNPLLCAFRCMNTFGSYECTCPI 1345
Query: 181 GYTLREN--VCRDVDECSRPRPVC--RNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNE 235
GY LRE+ +C+D+DEC+ C R C+NL G ++C C G P+ + CVD NE
Sbjct: 1346 GYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENE 1405
Query: 236 CREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE----CDELPHPCGRDGNP 291
CR +C NGRC N +GS+RCEC G+ ++ G C D + + L C +
Sbjct: 1406 CRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSS 1465
Query: 292 SCTNTNGGYECSCGAGWKLVGRRC--VDRDECKELPYVCAGGECRNFNGGYVCECPAGWR 349
T C G GW G +C + +C G +G + EC
Sbjct: 1466 RNLVTKSECCCDGGRGW---GHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPN 1522
Query: 350 FDKTAAVCVDERKEL-CYDEWEAGRCHRARPLQLARPECC-CSEGAAWGRYCERCPAPDS 407
T C++ C+ C ++ C E + + C
Sbjct: 1523 LC-TNGQCINTMGSFRCF-------CKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTE 1574
Query: 408 AEFMRICQGG--MGRPNLT-QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
+ C G + T +DLDEC+ + C CVNT G F C+CP G+
Sbjct: 1575 GSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQF-LCVNTLGGFTCKCPPGFT--QHHT 1631
Query: 465 SCVDADECALDPRICG-NGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTF 522
+C+D +EC P +CG G C NT G + C+C GF+ C DVDEC +G C
Sbjct: 1632 ACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDEC-DGNHRCQH 1690
Query: 523 RCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYR 581
C N G +RC CP GY C D +EC P C A C N +GSY C CP G+
Sbjct: 1691 GCQNILGGYRCGCPQGYIQHYQWNQCVDENEC-SNPNACGSASCYNTLGSYKCACPSGF- 1748
Query: 582 RTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
S Q S +AC D+NEC ++ C+ G C NT+G +LC C G+
Sbjct: 1749 --SFDQFS-SACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPPGY 1789
Score = 314 bits (772), Expect = 7e-85
Identities = 193/574 (33%), Positives = 257/574 (44%), Gaps = 45/574 (7%)
Query: 85 DTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRL 143
D FQ C +G+ + H R DV+EC C QC+N G+F C CP GY L
Sbjct: 1210 DDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSN-GQCINTDGSFRCECPMGYNL 1268
Query: 144 TPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENV-CRDVDECSRPRPVC 202
+ C D DEC C +G C N IGS+ C C G+ + C D++EC++ +C
Sbjct: 1269 DYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLC 1328
Query: 203 RNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVC--RNGRCRNTVGSFRCEC 259
C N G+Y C C G+ + C D++EC EG C R C+N +G+F C C
Sbjct: 1329 AF-RCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCIC 1387
Query: 260 APGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVD 317
PG DG C D +EC P C N C N G Y C C G++ G C+D
Sbjct: 1388 PPGMARRPDGEGCVDENECRTKPGICE---NGRCVNIIGSYRCECNEGFQSSSSGTECLD 1444
Query: 318 RDE----CKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVC----VDERKELCYDE 368
+ + L +C RN C C G + +C + K++C
Sbjct: 1445 NRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKIC--P 1502
Query: 369 WEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRP---NLTQ 425
G R + EC C F C+ G
Sbjct: 1503 HGPGYTTDGRDID----ECKVMPNLCTNGQCINT----MGSFRCFCKVGYTTDISGTSCI 1554
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
DLDEC P C C NT+GS++C CP GYVL DG +C D DEC C C
Sbjct: 1555 DLDECSQSPKPC-NYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNC-QFLCV 1612
Query: 486 NTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAA 543
NT GG+ C+C PGFTQ C+D +EC + C + C NT GSF C C G+++ A
Sbjct: 1613 NTLGGFTCKCPPGFTQH-HTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDA 1671
Query: 544 DGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQE 603
G++C D+DEC R C H C+N++G Y C CP+GY + N C D NEC
Sbjct: 1672 TGLNCEDVDECDGNHR-CQHGCQNILGGYRCGCPQGYIQ----HYQWNQCVDENECSNP- 1725
Query: 604 DLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
+ C C NT GS+ C C +GF + + C D
Sbjct: 1726 NACGSASCYNTLGSYKCACPSGFSFDQFSSACHD 1759
Score = 283 bits (694), Expect = 2e-75
Identities = 134/351 (38%), Positives = 184/351 (52%), Gaps = 19/351 (5%)
Query: 301 ECSCGAGW-KLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD 359
+ +C G ++ G C D +EC+ P VC G C N G + CECP G D T VC+D
Sbjct: 2 DTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLD 61
Query: 360 ERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMG 419
R E CY +W+ C P + CCC+ GAAWG CE CP P + E+ +C G G
Sbjct: 62 IRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAG 121
Query: 420 RPN----LT-----QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDAD 470
N LT +D++EC+ P +C G+C NT GSF+C C G+ L + +C D D
Sbjct: 122 FANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDID 181
Query: 471 ECALDPRICGNGTCSNTRGGYECQCSPGFTQG--PDQTCVDVDECAEGRASCT-FRCHNT 527
EC + P +CG+G C NT G +EC+C G+ G + C+D+DEC C C NT
Sbjct: 182 ECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNT 241
Query: 528 AGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAP 586
GSF+C CP G+ ++ C DI+EC +C + C N++G+Y C C GY+ T
Sbjct: 242 EGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDR 301
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
Q C DI+EC C C N++GS+ C C G+ DG C D
Sbjct: 302 Q----GCTDIDECMIMNGGCD-TQCTNSEGSYECSCSEGYALMPDGRSCAD 347
Score = 280 bits (687), Expect = 1e-74
Identities = 188/538 (34%), Positives = 250/538 (46%), Gaps = 80/538 (14%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C G P+ N + I+EC P LC C +T ++C C GY +C+D
Sbjct: 1301 CNCNEGFEPGPMMN-CEDINECAQNPLLCA-FRCMNTFGSYECTCPIGYALREDQKMCKD 1358
Query: 110 VDECSWGRPPC--RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQR-ICDHGD 166
+DEC+ G C RGM C NL G F C CPPG P + C D +EC + IC++G
Sbjct: 1359 LDECAEGLHDCESRGM-MCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGR 1417
Query: 167 CRNTIGSYRCECKPGYTLRENVCRDVDE----CSRP--RPVCRNGTCE-NLPGAYLCHCD 219
C N IGSYRCEC G+ + +D C + +C+ + NL C CD
Sbjct: 1418 CVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCD 1477
Query: 220 DG-----------------FKA----GPN--NDCVDVNECREGGMVCRNGRCRNTVGSFR 256
G +K GP D D++EC+ +C NG+C NT+GSFR
Sbjct: 1478 GGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFR 1537
Query: 257 CECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRR 314
C C GYT G +C D+DEC + P PC N C NT G Y+CSC G+ L G+
Sbjct: 1538 CFCKVGYTTDISGTSCIDLDECSQSPKPC----NYICKNTEGSYQCSCPRGYVLQEDGKT 1593
Query: 315 CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC 374
C D DEC+ + C C N GG+ C+CP G+ TA C D E G
Sbjct: 1594 CKDLDECQTKQHNCQF-LCVNTLGGFTCKCPPGFTQHHTA----------CIDNNECG-- 1640
Query: 375 HRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG--MGRPNLT-QDLDECR 431
++P C ++G C+ P S E CQ G + L +D+DEC
Sbjct: 1641 --------SQPSLCGAKGI-----CQNTPGSFSCE----CQRGFSLDATGLNCEDVDECD 1683
Query: 432 VRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGY 491
C G C N G +RC CP GY+ CVD +EC+ +P CG+ +C NT G Y
Sbjct: 1684 GNHR-CQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECS-NPNACGSASCYNTLGSY 1740
Query: 492 ECQCSPGFTQGP-DQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC 548
+C C GF+ C DV+EC+ + C + C NT G + C CP GY G HC
Sbjct: 1741 KCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQG-HC 1797
Score = 278 bits (682), Expect = 5e-74
Identities = 167/455 (36%), Positives = 213/455 (46%), Gaps = 63/455 (13%)
Query: 218 CDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV-- 275
C G C DVNEC VC NGRC N+ GSF CEC G TL GR C D+
Sbjct: 5 CPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRM 64
Query: 276 DEC------DELPHPC-GRDGNPSCTNTNG---GYEC-SC--------------GAGWK- 309
++C DE HP G+ +C G G EC C GAG+
Sbjct: 65 EQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFAN 124
Query: 310 ----LVGRRCV-DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKEL 364
L GR D +ECK P +C G+CRN G + C C +G+ D C D
Sbjct: 125 RGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTD----- 179
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLT 424
DE C P+ C S C P E + G
Sbjct: 180 -IDE-----CR-------ISPDLCGS------GICVNTPGSFECECFEGYESGFMMMKNC 220
Query: 425 QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTC 484
D+DEC P +C GG CVNT+GSF+C+CP G+ L+P CVD +EC+L +C NG C
Sbjct: 221 MDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKC 280
Query: 485 SNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAA 543
N G Y+C C+PG+ PD Q C D+DEC C +C N+ GS+ C+C GYA+
Sbjct: 281 VNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMP 340
Query: 544 DGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQ 602
DG C DIDEC P +C C N+ G Y C C +G+ A D + C D+NEC+
Sbjct: 341 DGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGF---MASMDMK-TCIDVNECDLN 396
Query: 603 EDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
++C G C NT GSF+C C G+ + T C D
Sbjct: 397 SNICMFGECENTKGSFICHCQLGYSVKKGTTGCTD 431
Score = 213 bits (521), Expect = 2e-54
Identities = 140/469 (29%), Positives = 195/469 (41%), Gaps = 59/469 (12%)
Query: 47 TALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHL 106
T +C PG P +EC P +C+ G C + ++C C+ G++ ++
Sbjct: 1382 TFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTE 1441
Query: 107 CRDVDE----CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRIC 162
C D + + C+ + NL EC C G + C ++IC
Sbjct: 1442 CLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKIC 1501
Query: 163 DHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
HG PGYT RD+DEC +C NG C N G++ C C G+
Sbjct: 1502 PHG--------------PGYTTDG---RDIDECKVMPNLCTNGQCINTMGSFRCFCKVGY 1544
Query: 223 KAG-PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDEL 281
C+D++EC + C N C+NT GS++C C GY L DG+ C+D+DEC
Sbjct: 1545 TTDISGTSCIDLDECSQSPKPC-NYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTK 1603
Query: 282 PHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVC-AGGECRNFNGGY 340
H C C NT GG+ C C G+ C+D +EC P +C A G C+N G +
Sbjct: 1604 QHNC----QFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSF 1659
Query: 341 VCECPAGWRFDKTAAVCVDERKELCYDEWEAG-RCHRARPLQLARPECCCSEGAAWGRYC 399
CEC G+ D T C D DE + RC L C C +G
Sbjct: 1660 SCECQRGFSLDATGLNCED------VDECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQW 1713
Query: 400 ERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVL 459
+C D +EC P+ C C NT GS++C CP G+
Sbjct: 1714 NQCV----------------------DENECS-NPNACGSASCYNTLGSYKCACPSGFSF 1750
Query: 460 APDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV 508
+C D +EC+ C G CSNT GGY C C PG+ + CV
Sbjct: 1751 DQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPPGYYRVGQGHCV 1798
Score = 167 bits (407), Expect = 1e-40
Identities = 134/476 (28%), Positives = 191/476 (40%), Gaps = 78/476 (16%)
Query: 453 CPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCV--- 508
CP G G++C D +EC + P +C NG C N++G + C+C G T G + C+
Sbjct: 5 CPRGLARIK-GVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIR 63
Query: 509 --------DVDECAE---GR----ASCTF-------RCHNT----AGSFRCTCPYGYAVA 542
D DEC G+ A C C + CP G A
Sbjct: 64 MEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFA 123
Query: 543 ADG------VHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACED 595
G +DI+EC P +C + C N +GS+ C+C G+ A E C D
Sbjct: 124 NRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGF----ALDMEERNCTD 179
Query: 596 INECEEQEDLCSGGVCINTDGSFLCDC----DAGFEPSEDGTDCIDR--------RTGTC 643
I+EC DLC G+C+NT GSF C+C ++GF ++ D ID R GTC
Sbjct: 180 IDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMD-IDECERNPLLCRGGTC 238
Query: 644 YRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPA- 702
+ S +C+ +C +G +C P
Sbjct: 239 VNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTY---QCSCNPGY 295
Query: 703 PGSPAR-----LDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLD--VFADVDECAAIP 755
+P R +D C +N D AD+DEC P
Sbjct: 296 QATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNP 355
Query: 756 GLC-------APGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCD-QLCHNTDGSYDCL 805
+C PG +RC+C G+ + ++ C DV+EC + C C NT GS+ C
Sbjct: 356 DICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICH 415
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV 859
C+ GY + + C DVDECE H C C N GS++CSC +G+ G C+
Sbjct: 416 CQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCI 471
Score = 134 bits (324), Expect = 1e-30
Identities = 73/217 (33%), Positives = 97/217 (44%), Gaps = 10/217 (4%)
Query: 69 DECDIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+EC P LC G C +TP F C C G+ D T C DVDEC G C+ C
Sbjct: 1637 NECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECD-GNHRCQH--GCQ 1693
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE- 186
N+ G + C CP GY ++C D +EC + C C NT+GSY+C C G++ +
Sbjct: 1694 NILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQF 1753
Query: 187 -NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN 245
+ C DV+ECS + C G C N G YLC C G+ CV +G + +
Sbjct: 1754 SSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKGQYLSLD 1812
Query: 246 GRC--RNTVGSFRC-ECAPGYTLTADGRNCRDVDECD 279
N + C EC D R R + E D
Sbjct: 1813 TEVDEENALSPEACYECKINGYSKKDSRQKRSIHEPD 1849
Score = 130 bits (315), Expect = 2e-29
Identities = 54/122 (44%), Positives = 71/122 (58%), Gaps = 9/122 (7%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHN 797
D+DEC +P LC G+ FRC C GY +G C D+DEC+ P PC+ +C N
Sbjct: 1513 DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKN 1572
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA 857
T+GSY C C GY L EDG C+D+DEC+ H CQ +C NT G + C C G+ + A
Sbjct: 1573 TEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTA 1632
Query: 858 CV 859
C+
Sbjct: 1633 CI 1634
Score = 101 bits (243), Expect = 8e-21
Identities = 49/125 (39%), Positives = 65/125 (52%), Gaps = 11/125 (8%)
Query: 746 ADVDECAAIPGLC-------APGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCH 796
+DVDECA LC PG +RC C G+ PA + C D+DEC+ + C+
Sbjct: 512 SDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCN 571
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KR 854
N G + C+C GYELD G NC D+DEC + +C NT G YEC+C ++
Sbjct: 572 NLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPT 631
Query: 855 GDACV 859
G CV
Sbjct: 632 GVGCV 636
Score = 97.9 bits (233), Expect = 1e-19
Identities = 46/113 (40%), Positives = 55/113 (48%), Gaps = 9/113 (7%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNT 798
D+DEC C G F C C PG+ C D +EC +P C +C NT
Sbjct: 1596 DLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNT 1655
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
GS+ C C+ G+ LD G NC DVDEC+ H CQ C N G Y C C GY
Sbjct: 1656 PGSFSCECQRGFSLDATGLNCEDVDECD-GNHRCQHGCQNILGGYRCGCPQGY 1707
Score = 95.5 bits (227), Expect = 7e-19
Identities = 50/125 (40%), Positives = 64/125 (51%), Gaps = 12/125 (9%)
Query: 747 DVDECA-AIP---GLCAP--GRFRCVCGPGYRPAGEV-CADVDECAVRPPPCDQLCHNTD 799
D DEC+ P G C G F C C G+ P + C D++ECA P C C NT
Sbjct: 1277 DTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTF 1336
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ---QICSNTEGSYECSCEDGYEKR-- 854
GSY+C C GY L ED C+D+DEC H C+ +C N G++ C C G +R
Sbjct: 1337 GSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPD 1396
Query: 855 GDACV 859
G+ CV
Sbjct: 1397 GEGCV 1401
Score = 93.5 bits (222), Expect = 3e-18
Identities = 49/122 (40%), Positives = 62/122 (50%), Gaps = 9/122 (7%)
Query: 747 DVDECAAIP---GLC--APGRFRCVCGPGYRPA-GEVCADVDECA-VRPPPC-DQLCHNT 798
DVDEC P G C G + C+C PG+ C D+DEC+ C + C N
Sbjct: 998 DVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNE 1057
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA 857
GS+ CLC GYEL DG NC D +EC +C C N EGS+ C C GYE + +
Sbjct: 1058 IGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN 1117
Query: 858 CV 859
C+
Sbjct: 1118 CI 1119
Score = 87.0 bits (206), Expect = 3e-16
Identities = 42/103 (40%), Positives = 53/103 (51%), Gaps = 5/103 (4%)
Query: 761 GRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDEDGA 817
G +RC C GY C D +EC+ P C C+NT GSY C C +G+ D+ +
Sbjct: 1697 GGYRCGCPQGYIQHYQWNQCVDENECS-NPNACGSASCYNTLGSYKCACPSGFSFDQFSS 1755
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
C DV+EC + C CSNTEG Y C C GY + G CV
Sbjct: 1756 ACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCV 1798
Score = 84.2 bits (199), Expect = 2e-15
Identities = 46/122 (37%), Positives = 58/122 (47%), Gaps = 13/122 (10%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAGEVCADVDECAVRPPPC--DQLCH 796
DVDEC C PG F+C C G+ G C D+DEC+ C + C
Sbjct: 431 DVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCV 490
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRG 855
NT GSY C C G+ DG C DVDEC + + C+ C N G+Y C CE G+
Sbjct: 491 NTPGSYRCACSEGF--TGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPAS 548
Query: 856 DA 857
D+
Sbjct: 549 DS 550
Score = 83.4 bits (197), Expect = 3e-15
Identities = 47/125 (37%), Positives = 58/125 (46%), Gaps = 15/125 (12%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQ--LC 795
DV+EC +C G F C C GY + C DVDEC + CD C
Sbjct: 389 DVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASC 448
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEK 853
N GS+ C CR G+ +G C D+DEC TH C C NT GSY C+C +G+
Sbjct: 449 LNIPGSFKCSCREGWI--GNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTG 506
Query: 854 RGDAC 858
G C
Sbjct: 507 DGFTC 511
Score = 79.0 bits (186), Expect = 7e-14
Identities = 42/118 (35%), Positives = 58/118 (49%), Gaps = 12/118 (10%)
Query: 747 DVDECAAIPGLCAP------GRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQ---LC 795
D++ECA P LCA G + C C GY R ++C D+DECA C+ +C
Sbjct: 1317 DINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMC 1376
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE 852
N G++ C+C G DG C D +EC C+ C N GSY C C +G++
Sbjct: 1377 KNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQ 1434
Score = 77.8 bits (183), Expect = 2e-13
Identities = 45/125 (36%), Positives = 59/125 (47%), Gaps = 13/125 (10%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYRPAGEVCADVDECAVRPPPC-DQLCHNT 798
D +EC A+PG C+PG FRC+C PGY E C D++EC P C C NT
Sbjct: 1080 DTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTNT 1139
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICS-----NTEGSYECSCEDGYEK 853
G + CLC G+ L ++G C D + T+ CS NT + C + E
Sbjct: 1140 PGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEG 1199
Query: 854 RGDAC 858
GD C
Sbjct: 1200 WGDPC 1204
Score = 70.5 bits (165), Expect = 2e-11
Identities = 41/115 (35%), Positives = 48/115 (41%), Gaps = 11/115 (9%)
Query: 747 DVDECAAIPGLCA--------PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCH 796
D +EC + P LC PG F C C G+ G C DVDEC C C
Sbjct: 1635 DNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHR-CQHGCQ 1693
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
N G Y C C GY C D +EC C NT GSY+C+C G+
Sbjct: 1694 NILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGF 1748
Score = 67.7 bits (158), Expect = 2e-10
Identities = 38/106 (35%), Positives = 55/106 (51%), Gaps = 10/106 (9%)
Query: 763 FRCVCG--PGYR---PAGEVCADVDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDG 816
F+ +CG PG+ G+ D+DEC P C + +C N GS+ C C TG+ ++
Sbjct: 851 FKTICGNIPGFTFDIHTGKA-VDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLL 909
Query: 817 ANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE-KRGDACV 859
C D+DEC + CQ+ C N+ GSY C C G++ ACV
Sbjct: 910 LVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACV 955
Score = 64.9 bits (151), Expect = 1e-09
Identities = 41/121 (33%), Positives = 56/121 (46%), Gaps = 14/121 (11%)
Query: 747 DVDECA----AIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPC-DQLCHN 797
D+DEC+ + G C PG F C+C GY G C D+DECA P C + LC N
Sbjct: 555 DIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECA-DPINCVNGLCVN 613
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA 857
T G Y+C C ++L+ G C D R + + +GS C+ E G +
Sbjct: 614 TPGRYECNCPPDFQLNPTGVGCVD----NRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSS 669
Query: 858 C 858
C
Sbjct: 670 C 670
Score = 64.1 bits (149), Expect = 2e-09
Identities = 35/99 (35%), Positives = 43/99 (43%), Gaps = 9/99 (9%)
Query: 761 GRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGA 817
G F C+C PG RP GE C D +EC +P C+ C N GSY C C G++ G
Sbjct: 1381 GTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGT 1440
Query: 818 NCRDVDECERDTHTCQQICSNTEGS------YECSCEDG 850
C D + Q IC S EC C+ G
Sbjct: 1441 ECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGG 1479
>U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein.
Length = 2911
Score = 622 bits (1536), Expect = e-177
Identities = 286/719 (39%), Positives = 395/719 (54%), Gaps = 44/719 (6%)
Query: 9 SCAGAVGVPQTKYLCCCS--VGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETK 66
+C + TK +CCC+ VG A PCE CP G+ +CG PG + T +
Sbjct: 1747 TCENELPFNVTKRMCCCTYNVGKAGNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAV 1806
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
IDEC +P +C G C + F+C C G+ +++ +C D+DECS G C+ A C
Sbjct: 1807 DIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADC 1866
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTLR 185
+N PG++ C C G++L+P+ C D +EC + +C HG C + GSY+C C G+
Sbjct: 1867 INSPGSYRCECAAGFKLSPN-GACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKAS 1925
Query: 186 EN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE-GGMV 242
++ +C DVDEC R P C NGTC+N G+Y C C GF+ NNDC+D++EC G V
Sbjct: 1926 QDQTMCMDVDECER-HP-CGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQV 1983
Query: 243 CRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC 302
CRNGRC N +GSF+C C GY LT DG+NC D +EC LP C +C N G + C
Sbjct: 1984 CRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPG---TCQNLEGSFRC 2040
Query: 303 SCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
C G+++ C+D +EC E P +C G C N GG+ C CP G+ C D R+
Sbjct: 2041 ICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQ 2100
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCSE--GAAWGRYCERCPAPDSAEFMRICQGGMGR 420
C+ +E G+C + + +CCCS+ G WG CE CP D F +C G G
Sbjct: 2101 SFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGT 2160
Query: 421 -PNL---TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDP 476
P+L +D++EC P +C G+C+NTDGSFRCECP GY L G+ CVD DEC++
Sbjct: 2161 VPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIG- 2219
Query: 477 RICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCP 536
CGNGTC+N G +EC C+ GF GP C D++ECA+ C RC NT GS+ CTCP
Sbjct: 2220 NPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCALRCMNTFGSYECTCP 2279
Query: 537 YGYAVAADGVHCRDIDECVQEPRVCPH---ACENVVGSYICKCPEGYRRTSAPQDSENAC 593
GYA+ D C+D+DEC + C C+N++G+++C CP G R D E C
Sbjct: 2280 IGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARR---PDGE-GC 2335
Query: 594 EDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCE 653
D NEC + +C G C+N GS+ C+C+ GF+ S GT+C+D R G C+ ++ C+
Sbjct: 2336 VDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQ 2395
Query: 654 PEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLC 712
VTK++CCC G WG +CELCP PG+ +C
Sbjct: 2396 ------------------MASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKIC 2436
Score = 471 bits (1161), Expect = e-132
Identities = 262/740 (35%), Positives = 355/740 (47%), Gaps = 80/740 (10%)
Query: 151 EDVDECGDQ-RICDHGDCRNTIGSYRCECKPGYTLRENV-CRDVDECSRPRPVCRNGTCE 208
+ +D C +C +G C T+ SYRCEC GY N C DVDEC+ P C NG C
Sbjct: 492 QTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTS-NP-CTNGDCV 549
Query: 209 NLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTA 267
N PG+Y C C GF+ P C+D++EC + G++C+NGRC N+ GSF+C C G+ LT
Sbjct: 550 NTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNSDGSFQCICNAGFELTT 609
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELP 325
DG+NC D DEC + C N C N +G ++C C G+ L GR C D DEC + P
Sbjct: 610 DGKNCVDHDECTTT-NMCL---NGMCINEDGSFKCICKPGFVLAPNGRYCTDVDEC-QTP 664
Query: 326 YVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER-KELCYDEWEAGRCHRARPLQLAR 384
+C G C N G + C+CP G VCVD + CY + G C R P + +
Sbjct: 665 GICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTK 724
Query: 385 PECCCSE-GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCV 443
ECCC+ +G C+ CPA +SAEF +C G+G +D++EC + PD+C G C
Sbjct: 725 SECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICE 784
Query: 444 NTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QG 502
N GS+RC C GY G +C+D DEC ++ +C NG C NT G Y C C PG+ +
Sbjct: 785 NLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRT 844
Query: 503 PDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI--DEC---VQE 557
+TC D++EC E C N GSF C C G +++ G+ C D C +Q+
Sbjct: 845 ETETCEDINEC-ESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQD 903
Query: 558 PR---------VCPHACENVVGSYICKCPEGYRRTSAPQDSEN----ACEDINECEEQED 604
R + C + ++ C T+ P+ CED+NECE
Sbjct: 904 SRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPG 963
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXX 664
+C G C+N+ GSF C+C G G C+D R CY C
Sbjct: 964 VCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDEC------------ 1011
Query: 665 XXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXX 724
G CCC +GAAWG+ECE CP PG+ LC
Sbjct: 1012 --------IHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCP----------- 1052
Query: 725 XXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCAPGR-------FRCVCGPGYRPAGEV 777
+ D++EC A PG+C G+ F+C C G+ E
Sbjct: 1053 ---RGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEE 1109
Query: 778 --CADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD-EDGANCRDVDECERDTHTCQ 833
C D+DEC + P C +C NT GS++C C GYE NC D+D CER+ C+
Sbjct: 1110 RNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCR 1169
Query: 834 -QICSNTEGSYECSCEDGYE 852
C NTEGS++C C G+E
Sbjct: 1170 GGTCVNTEGSFQCDCPLGHE 1189
Score = 455 bits (1121), Expect = e-127
Identities = 295/845 (34%), Positives = 372/845 (44%), Gaps = 131/845 (15%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
ID C+ P LC+ GTC +T FQC C G+E + C D++ECS CR +CV
Sbjct: 1158 IDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRN-GKCV 1216
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
N+ G ++C C PGY+ TP C D+DEC C N+ GSY C C GY L +
Sbjct: 1217 NMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPD 1276
Query: 188 --VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCR 244
C D+DEC +C G C N+PG Y C C DGF A + C+DVNEC +C
Sbjct: 1277 GRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICM 1336
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
G C NT GSF C C GY++ C DVDEC+ H C D + SC N G ++CSC
Sbjct: 1337 FGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNC--DMHASCLNIPGSFKCSC 1394
Query: 305 GAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
GW G +C+D DEC + C+ +C N G Y C C G+ D VDE E
Sbjct: 1395 REGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAE 1454
Query: 364 LCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNL 423
+ E G+C C C G PA DS R CQ
Sbjct: 1455 NI-NLCENGQCLNVPGAY----RCECEMGFT--------PASDS----RSCQ-------- 1489
Query: 424 TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT 483
D+DEC + ++CV G C N G F C C DGY L G +C D DECA DP C NG
Sbjct: 1490 --DIDECSFQ-NICVSGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECA-DPINCVNGL 1545
Query: 484 CSNTRGGYECQCSPGFTQGPDQT-CVD--VDEC-------AEGRASCTFRCHNTAGSFRC 533
C NT G YEC C P F P CVD V C +G SC C
Sbjct: 1546 CVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSC 1605
Query: 534 TCPYG------------------YAVAADGVHCR---------DIDECVQEPRVCPHA-C 565
C G Y + G R DIDEC + P +C C
Sbjct: 1606 CCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNC 1665
Query: 566 ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
N GS+ C+CP+GY + + CEDI+EC +C G C NT G++ C C
Sbjct: 1666 INTFGSFQCECPQGYYLS----EDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPE 1721
Query: 626 FEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQC 685
+ G +C+D R CYRS CE E +VTK C
Sbjct: 1722 YMQVNGGHNCMDMRKSFCYRSYNGTTCENELPF--------------------NVTKRMC 1761
Query: 686 CCT--LGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLD 743
CCT +G A CE CP PG+ D T P
Sbjct: 1762 CCTYNVGKAGNKPCEPCPTPGT---ADFKTICGNIPGFTFDIHTGKA------------- 1805
Query: 744 VFADVDECAAIPGLCAP-------GRFRCVCGPG--YRPAGEVCADVDECAVRPPPCDQL 794
D+DEC IPG+CA G FRC C G Y VC D+DEC+ C +
Sbjct: 1806 --VDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRN 1863
Query: 795 --CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGY 851
C N+ GSY C C G++L +GA C D +EC + C +C + +GSY+C C +G+
Sbjct: 1864 ADCINSPGSYRCECAAGFKLSPNGA-CVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGF 1922
Query: 852 EKRGD 856
+ D
Sbjct: 1923 KASQD 1927
Score = 442 bits (1090), Expect = e-123
Identities = 235/634 (37%), Positives = 321/634 (50%), Gaps = 61/634 (9%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDE-----------CSWG 116
I+ECD P +C G+C +TP GFQC C G+ + C D + CS
Sbjct: 2056 INECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVP 2115
Query: 117 RP--PCRGMAQCVNLPG----------------AFECRCPPGYRLTPSL-DECEDVDECG 157
+ + C +PG AF+ CP G+ PSL D EDV+EC
Sbjct: 2116 KAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECL 2175
Query: 158 DQR-ICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAY 214
+ IC +G C NT GS+RCEC GY L C D DECS P C NGTC N+ G++
Sbjct: 2176 ESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP-CGNGTCTNVIGSF 2234
Query: 215 LCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRD 274
C+C++GF+ GP +C D+NEC + ++C RC NT GS+ C C GY L D + C+D
Sbjct: 2235 ECNCNEGFEPGPMMNCEDINECAQNPLLCAL-RCMNTFGSYECTCPIGYALREDQKMCKD 2293
Query: 275 VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW--KLVGRRCVDRDECKELPYVCAGGE 332
+DEC E H C G C N G + C C G + G CVD +EC+ P +C G
Sbjct: 2294 LDECAEGLHDCESRGM-MCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGR 2352
Query: 333 CRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQ--LARPECCCS 390
C N G Y CEC G++ + C+D R+ LC+ E C A + + + ECCC
Sbjct: 2353 CVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCD 2412
Query: 391 EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFR 450
G WG CE CP P +A++ +IC G G +D+DEC+V P++C G+C+NT GSFR
Sbjct: 2413 GGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFR 2472
Query: 451 CECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVD 509
C C GY G SC+D DEC+ P+ C N C NT G Y+C C G+ Q +TC D
Sbjct: 2473 CFCKVGYTTDISGTSCIDLDECSQSPKPC-NYICKNTEGSYQCSCPRGYVLQEDGKTCKD 2531
Query: 510 VDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC--PHACEN 567
+DEC + +C F C NT G F C CP G+ C D +EC +P +C C+N
Sbjct: 2532 LDECQTKQHNCQFLCVNTLGGFTCKCPPGF--TQHHTACIDNNECGSQPLLCGGKGICQN 2589
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
GS+ C+C G+ + + CED++EC+ C G C N G + C C G+
Sbjct: 2590 TPGSFSCECQRGFSLDATGLN----CEDVDECDGNH-RCQHG-CQNILGGYRCGCPQGYI 2643
Query: 628 PSEDGTDCIDRR---------TGTCYRSLVSGRC 652
C+D + +CY +L S +C
Sbjct: 2644 QHYQWNQCVDENECSNPNACGSASCYNTLGSYKC 2677
Score = 422 bits (1039), Expect = e-117
Identities = 310/954 (32%), Positives = 399/954 (41%), Gaps = 135/954 (14%)
Query: 19 TKYLCCCSVGH---AWGAPCEACPPRGSPAHTALCGEKPGEYI---------NPVTNETK 66
+ Y C C++G+ A G + +P C PG Y P
Sbjct: 514 SSYRCECNMGYKQDANGDCIDVDECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACI 573
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
IDEC LCK G C ++ FQC C+ G+E C D DEC+ GM C
Sbjct: 574 DIDECIQNGVLCKNGRCVNSDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGM--C 631
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYT--L 184
+N G+F+C C PG+ L P+ C DVDEC IC +G C N+ GS+RC+C PG +
Sbjct: 632 INEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGM 691
Query: 185 RENVCRDVDECSRPRPVCRNGTC-ENLPGAYL---CHC---DDGF--------------- 222
VC D S + G C PGA C C D GF
Sbjct: 692 DGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEF 751
Query: 223 ------KAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVD 276
G D D+NEC +C NG C N GS+RC C GY A GRNC D+D
Sbjct: 752 HGLCSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDID 811
Query: 277 ECDELPHPCGRDGNPSCTNTNGGYECSCGAGW--KLVGRRCVDRDECKELPYVCAGGECR 334
EC C N C NT G Y C+C G+ + C D +EC+ P C G CR
Sbjct: 812 ECLVNRLLC---DNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNP--CVNGACR 866
Query: 335 NFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAA 394
N G + CEC G + T +C+D K C+ + RC + ECC + GAA
Sbjct: 867 NNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAA 926
Query: 395 WGRYCERCPAPDSAEFMRICQGGMGR-PNLT-QDLDECRVRPDVCVGGRCVNTDGSFRCE 452
WG CERC E C G+ R +T +D++EC V P VC GRCVN+ GSF CE
Sbjct: 927 WGSPCERC------ELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCE 980
Query: 453 CPDGYVLAPDGLSCV-----------DADEC--------ALDPRICGNGTCSNT------ 487
CP+G L G C+ D DEC +D C G T
Sbjct: 981 CPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECP 1040
Query: 488 RGG---YECQC--SPGFTQGPDQTC-----VDVDECAEGRASCTF-RCHNTAGSFRCTCP 536
+ G YE C GF D D++EC CT+ +C NT GSF+C C
Sbjct: 1041 KPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCN 1100
Query: 537 YGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACED 595
G+A+ + +C DIDEC P +C C N GS+ C+C EGY S +N C D
Sbjct: 1101 SGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYE--SGFMMMKN-CMD 1157
Query: 596 INECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID----------RRTGTCYR 645
I+ CE LC GG C+NT+GSF CDC G E S DC+D R G C
Sbjct: 1158 IDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVN 1217
Query: 646 SLVSGRCE--------PEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAW---G 694
+ + +C P+ +C C+ G A G
Sbjct: 1218 MIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDG 1277
Query: 695 SEC-ELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDV-FADVDECA 752
C ++ +P D+C T +DV D++
Sbjct: 1278 RSCADIDECENNP---DICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNI 1334
Query: 753 AIPGLC--APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLC 806
+ G C G F C C GY + C DVDEC + CD C N GS+ C C
Sbjct: 1335 CMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSC 1394
Query: 807 RTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDAC 858
R G+ +G C D+DEC TH C C NT GSY C+C +G+ G C
Sbjct: 1395 REGW--IGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTC 1446
Score = 397 bits (977), Expect = e-109
Identities = 227/635 (35%), Positives = 300/635 (47%), Gaps = 54/635 (8%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C G + P IDEC+ P +C G C + P ++C C G+ C D
Sbjct: 1265 CSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCID 1324
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG-DQRICD-HGDC 167
V+EC C +C N G+F C C GY + C DVDEC CD H C
Sbjct: 1325 VNECDLNSNICM-FGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASC 1383
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGP 226
N GS++C C+ G+ C D+DECS C N C N PG+Y C C +GF G
Sbjct: 1384 LNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGF-TGD 1442
Query: 227 NNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C DV+EC E +C NG+C N G++RCEC G+T +D R+C+D+DEC + C
Sbjct: 1443 GFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECS-FQNICV 1501
Query: 287 RDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
+ +C N G + C C G++L G C D DEC + P C G C N G Y C C
Sbjct: 1502 ---SGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECAD-PINCVNGLCVNTPGRYECNC 1557
Query: 345 PAGWRFDKTAAVCVDERKELCYDEWEAG-----RCHRARPLQLARPECCCSEGAAWGRYC 399
P ++ + T CVD R CY ++ C+ + ++R CCCS G AWG C
Sbjct: 1558 PPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPC 1617
Query: 400 ERCPAPDSAEFMRICQGGMG-RPN----LTQDLDECRVRPDVCVGGRCVNTDGSFRCECP 454
E CP +S E+ +C GG G RPN + +D+DEC+ P +C GG C+NT GSF+CECP
Sbjct: 1618 ETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECP 1677
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ-GPDQTCVDVDEC 513
GY L+ D C D DEC P +CG GTC NT G Y C C P + Q C+D+ +
Sbjct: 1678 QGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKS 1737
Query: 514 AEGRASCTFRCHN----TAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVV 569
R+ C N C C Y A + C EP P +
Sbjct: 1738 FCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAGN-------KPC--EPCPTPGTAD--- 1785
Query: 570 GSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPS 629
IC G+ DI+EC+E +C+ GVCIN GSF C+C GF +
Sbjct: 1786 FKTICGNIPGF----TFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYN 1841
Query: 630 ------EDGTDC-----IDRRTGTCYRSLVSGRCE 653
ED +C + +R C S S RCE
Sbjct: 1842 DLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCE 1876
Score = 396 bits (974), Expect = e-109
Identities = 276/841 (32%), Positives = 371/841 (44%), Gaps = 137/841 (16%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD--VDECSWGRPPCRGMAQ 125
IDEC P C G C +TP ++C C ++ + T C D V C P RG
Sbjct: 1532 IDEC-ADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGP-RG--- 1586
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
G+ C G ++ S C G+ C+ N+ Y C G R
Sbjct: 1587 ----DGSLSCNTEIGVGVSRSSCCCSLGKAWGNP--CETCPPVNSTEYYTL-CPGGEGFR 1639
Query: 186 EN----VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGG 240
N + D+DEC +C+ G C N G++ C C G+ + C D++EC
Sbjct: 1640 PNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHP 1699
Query: 241 MVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE-----------CD-ELP------ 282
VC G C NT+G++ C C P Y G NC D+ + C+ ELP
Sbjct: 1700 GVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKR 1759
Query: 283 -----HPCGRDGNPSC----TNTNGGYECSCGA----GWKLVGRRCVDRDECKELPYVCA 329
+ G+ GN C T ++ CG + + + VD DECKE+P +CA
Sbjct: 1760 MCCCTYNVGKAGNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICA 1819
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
G C N G + CECP G+ ++ VC D DE C L +C
Sbjct: 1820 NGVCINQIGSFRCECPTGFSYNDLLLVCED------IDE-----CSNGDNLCQRNADCIN 1868
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
S G+ RC + A ++ G D +EC P+VC G CV+ GS+
Sbjct: 1869 SPGSY------RC---ECAAGFKLSPNGA-----CVDRNECLEIPNVCSHGLCVDLQGSY 1914
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVD 509
+C C +G+ + D C+D DEC P CGNGTC NT G Y C C PGF + C+D
Sbjct: 1915 QCICHNGFKASQDQTMCMDVDECERHP--CGNGTCKNTVGSYNCLCYPGFELTHNNDCLD 1972
Query: 510 VDECAE--GRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC-PHACE 566
+DEC+ G+ RC N GSF+C C GY + DG +C D +ECV P C P C+
Sbjct: 1973 IDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQ 2032
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
N+ GS+ C CP GY SEN C DINEC+E ++C G C NT G F C C GF
Sbjct: 2033 NLEGSFRCICPPGYE-----VKSEN-CIDINECDEDPNICLFGSCTNTPGGFQCLCPPGF 2086
Query: 627 EPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCC 686
S++G C D R C+ + +G+C + TKA+CC
Sbjct: 2087 VLSDNGRRCFDTRQSFCFTNFENGKCSVPKAF--------------------NTTKAKCC 2126
Query: 687 CTL--GAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDV 744
C+ G WG CELCP A DLC + T D
Sbjct: 2127 CSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLH-------------------DT 2167
Query: 745 FADVDECAAIPGLCAPGR-------FRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLC 795
DV+EC PG+C+ G+ FRC C GY G C D DEC++ P + C
Sbjct: 2168 REDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTC 2227
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
N GS++C C G+E NC D++EC ++ C C NT GSYEC+C GY R
Sbjct: 2228 TNVIGSFECNCNEGFE-PGPMMNCEDINECAQNPLLCALRCMNTFGSYECTCPIGYALRE 2286
Query: 856 D 856
D
Sbjct: 2287 D 2287
Score = 389 bits (957), Expect = e-107
Identities = 216/597 (36%), Positives = 292/597 (48%), Gaps = 54/597 (9%)
Query: 1 MEWNEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
++W+E++ C V CCC+VG AWG CE CP G+ + LC G + N
Sbjct: 1004 LKWDEDE--CIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAG-FANR 1060
Query: 61 ---VTNET--KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSW 115
+T K I+EC P +C G C +T F+C C+ G+ D C D+DEC
Sbjct: 1061 GDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRI 1120
Query: 116 GRPPCRGMAQCVNLPGAFECRCPPGYRLT-PSLDECEDVDECG-DQRICDHGDCRNTIGS 173
C G CVN PG+FEC C GY + C D+D C + +C G C NT GS
Sbjct: 1121 SPDLC-GSGICVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGS 1179
Query: 174 YRCECKPGYTL---RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND- 229
++C+C G+ L RE+ C D++ECS +CRNG C N+ G Y C C+ G++A P+
Sbjct: 1180 FQCDCPLGHELSPSRED-CVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQG 1238
Query: 230 CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDG 289
C D++EC C + +C N+ GS+ C C+ GY L DGR+C D+DEC+ P C DG
Sbjct: 1239 CTDIDECMIMNGGC-DTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDIC--DG 1295
Query: 290 NPSCTNTNGGYECSCGAGW--KLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
CTN G Y C C G+ + + C+D +EC +C GEC N G ++C C G
Sbjct: 1296 G-QCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLG 1354
Query: 348 WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS 407
+ K C D DE E G H C A+ C P
Sbjct: 1355 YSVKKGTTGCTD------VDECEIG-AHN------------CDMHAS----CLNIP---- 1387
Query: 408 AEFMRIC-QGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLS 465
F C +G +G DLDEC C + +CVNT GS+RC C +G+ DG +
Sbjct: 1388 GSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGF--TGDGFT 1445
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRC 524
C D DECA + +C NG C N G Y C+C GFT D ++C D+DEC+ + C
Sbjct: 1446 CSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVSGTC 1505
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
+N G F C C GY + G +C DIDEC C N G Y C CP ++
Sbjct: 1506 NNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQ 1562
Score = 362 bits (891), Expect = 3e-99
Identities = 223/663 (33%), Positives = 301/663 (45%), Gaps = 75/663 (11%)
Query: 9 SCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPI 68
SC +GV ++ CCCS+G AWG PCE CPP S + LC G NP+T + I
Sbjct: 1591 SCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDI 1650
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC +P LC+ G C +T FQC C GY + +C D+DEC + P G C N
Sbjct: 1651 DECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDEC-FAHPGVCGPGTCYN 1709
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTI--GSYRCECKPGYTLRE 186
G + C CPP Y C D+ + R + C N + + C Y + +
Sbjct: 1710 TLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGK 1769
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
+ + C P C N+PG + G KA VD++EC+E +C NG
Sbjct: 1770 AGNKPCEPCPTPGTADFKTICGNIPG-FTFDIHTG-KA------VDIDECKEIPGICANG 1821
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
C N +GSFRCEC G++ C D+DEC + C R N C N+ G Y C C A
Sbjct: 1822 VCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQR--NADCINSPGSYRCECAA 1879
Query: 307 GWKL-VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
G+KL CVDR+EC E+P VC+ G C + G Y C C G++ + +C+D
Sbjct: 1880 GFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMD------ 1933
Query: 366 YDEWEAGRCHRAR-PLQLARPECCCSEGAAWGRYCERCPAPDSAEFM-RICQGGMGRPNL 423
DE E C + C C G + + + F ++C+ G
Sbjct: 1934 VDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNG------ 1987
Query: 424 TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT 483
RC N GSF+C C +GY L PDG +C+D +EC P C GT
Sbjct: 1988 -----------------RCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGT 2030
Query: 484 CSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYAVA 542
C N G + C C PG+ + + C+D++EC E C F C NT G F+C CP G+ ++
Sbjct: 2031 CQNLEGSFRCICPPGY-EVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLS 2089
Query: 543 ADGVHCRDIDE--CVQ--EPRVC--PHACENVVGSYIC-KCP-EGYRRTS--APQDSENA 592
+G C D + C E C P A C K P EG+ P+D E A
Sbjct: 2090 DNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVA 2149
Query: 593 ----C--------------EDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTD 634
C ED+NEC E +CS G CINTDGSF C+C G+ G
Sbjct: 2150 FQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVR 2209
Query: 635 CID 637
C+D
Sbjct: 2210 CVD 2212
Score = 359 bits (884), Expect = 2e-98
Identities = 220/645 (34%), Positives = 296/645 (45%), Gaps = 48/645 (7%)
Query: 4 NEEDQSCAGAVGVPQTKYLCCCSV--GHAWGAPCEACPPRGSPAHTALCGEKPGEYINPV 61
N E+ C+ TK CCCS G WG PCE CP A LC G P
Sbjct: 2106 NFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTV--PS 2163
Query: 62 TNETKP-IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
++T+ ++EC P +C G C +T F+C C GY D T C D DECS G P C
Sbjct: 2164 LHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP-C 2222
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
G C N+ G+FEC C G+ P ++ CED++EC + C NT GSY C C
Sbjct: 2223 -GNGTCTNVIGSFECNCNEGFEPGPMMN-CEDINECAQNPLLCALRCMNTFGSYECTCPI 2280
Query: 181 GYTLREN--VCRDVDECSRPRPVC--RNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNE 235
GY LRE+ +C+D+DEC+ C R C+NL G ++C C G P+ + CVD NE
Sbjct: 2281 GYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENE 2340
Query: 236 CREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE----CDELPHPCGRDGNP 291
CR +C NGRC N +GS+RCEC G+ ++ G C D + + L C +
Sbjct: 2341 CRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSS 2400
Query: 292 SCTNTNGGYECSCGAGWKLVGRRC--VDRDECKELPYVCAGGECRNFNGGYVCECPAGWR 349
T C G GW G +C + +C G +G + EC
Sbjct: 2401 RNLVTKSECCCDGGRGW---GHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPN 2457
Query: 350 FDKTAAVCVDERKEL-CYDEWEAGRCHRARPLQLARPECC-CSEGAAWGRYCERCPAPDS 407
T C++ C+ C ++ C E + + C
Sbjct: 2458 LC-TNGQCINTMGSFRCF-------CKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTE 2509
Query: 408 AEFMRICQGG--MGRPNLT-QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
+ C G + T +DLDEC+ + C CVNT G F C+CP G+
Sbjct: 2510 GSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQF-LCVNTLGGFTCKCPPGFT--QHHT 2566
Query: 465 SCVDADECALDPRICGN-GTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTF 522
+C+D +EC P +CG G C NT G + C+C GF+ C DVDEC +G C
Sbjct: 2567 ACIDNNECGSQPLLCGGKGICQNTPGSFSCECQRGFSLDATGLNCEDVDEC-DGNHRCQH 2625
Query: 523 RCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYR 581
C N G +RC CP GY C D +EC P C A C N +GSY C CP G+
Sbjct: 2626 GCQNILGGYRCGCPQGYIQHYQWNQCVDENEC-SNPNACGSASCYNTLGSYKCACPSGF- 2683
Query: 582 RTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
S Q S +AC D+NEC ++ C+ G C NT+G +LC C G+
Sbjct: 2684 --SFDQFS-SACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPPGY 2724
Score = 357 bits (877), Expect = 1e-97
Identities = 221/681 (32%), Positives = 318/681 (46%), Gaps = 96/681 (14%)
Query: 4 NEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTN 63
N +D C + K CC ++G AWG+PCE C TA C I VT
Sbjct: 900 NIQDSRCEVNINGATLKSECCATLGAAWGSPCERCE-----LDTA-CPRGLAR-IKGVTC 952
Query: 64 ETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDV--DEC--SWGRPP 119
E ++EC++ P +C G C ++ F C C G D T +C D+ ++C W
Sbjct: 953 ED--VNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDE 1010
Query: 120 C--------RGMAQCVNLPGAF--ECR-CP-PGYRLTPSLDE-----------------C 150
C R A C + A+ EC CP PG + +L
Sbjct: 1011 CIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFY 1070
Query: 151 EDVDEC-GDQRICDHGDCRNTIGSYRCECKPGYTL--RENVCRDVDECSRPRPVCRNGTC 207
+D++EC +C +G CRNTIGS++C C G+ L E C D+DEC +C +G C
Sbjct: 1071 KDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGIC 1130
Query: 208 ENLPGAYLCHCDDGFKAG--PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTL 265
N PG++ C C +G+++G +C+D++ C ++CR G C NT GSF+C+C G+ L
Sbjct: 1131 VNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHEL 1190
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKE 323
+ +C D++EC + C R+G C N G Y+CSC G++ R C D DEC
Sbjct: 1191 SPSREDCVDINECSLSDNLC-RNGK--CVNMIGTYQCSCNPGYQATPDRQGCTDIDECMI 1247
Query: 324 LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLA 383
+ C +C N G Y C C G+ C D DE E
Sbjct: 1248 MNGGC-DTQCTNSEGSYECSCSEGYALMPDGRSCAD------IDECENN----------- 1289
Query: 384 RPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG-MGRPNLTQ--DLDECRVRPDVCVGG 440
P+ C G C P E+ +C G M ++ D++EC + ++C+ G
Sbjct: 1290 -PDICD------GGQCTNIPG----EYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFG 1338
Query: 441 RCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQCSPGF 499
C NT GSF C C GY + C D DEC + C + +C N G ++C C G+
Sbjct: 1339 ECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGW 1398
Query: 500 TQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQE 557
G C+D+DEC+ G C+ +C NT GS+RC C G+ DG C D+DEC +
Sbjct: 1399 I-GNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFT--GDGFTCSDVDECAEN 1455
Query: 558 PRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDG 616
+C + C NV G+Y C+C G+ P +C+DI+EC Q ++C G C N G
Sbjct: 1456 INLCENGQCLNVPGAYRCECEMGF----TPASDSRSCQDIDECSFQ-NICVSGTCNNLPG 1510
Query: 617 SFLCDCDAGFEPSEDGTDCID 637
F C CD G+E G +C D
Sbjct: 1511 MFHCICDDGYELDRTGGNCTD 1531
Score = 330 bits (811), Expect = 1e-89
Identities = 262/901 (29%), Positives = 368/901 (40%), Gaps = 138/901 (15%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+DEC P C G C +TP + C C G++ T C D+DEC C+ +CV
Sbjct: 535 VDECTSNP--CTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKN-GRCV 591
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
N G+F+C C G+ LT C D DEC +C +G C N GS++C CKPG+ L N
Sbjct: 592 NSDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPN 651
Query: 188 --VCRDVDECSRPRPVCRNGTCENLPGAY---------------LC---H----CDDGFK 223
C DVDEC P +C NG C N G++ +C H C G K
Sbjct: 652 GRYCTDVDECQTPG-ICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIK 710
Query: 224 AG----------PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR 273
G ++C N G C+ +N+ F C+ G +T DGR
Sbjct: 711 KGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSA-EFHGLCSSGVGITVDGR--- 766
Query: 274 DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK--LVGRRCVDRDECKELPYVCAGG 331
D++EC P C N C N G Y C+C +G++ GR C+D DEC +C G
Sbjct: 767 DINECALDPDICA---NGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNG 823
Query: 332 ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC-HRARPLQLARPECCCS 390
CRN G Y C CP G+ F C D +E E+ C + A L C CS
Sbjct: 824 LCRNTPGSYSCTCPPGYVFRTETETCED------INECESNPCVNGACRNNLGSFNCECS 877
Query: 391 EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFR 450
G+ C DS + C + +++ ++ + C R
Sbjct: 878 PGSKLSSTGLICI--DSLK--GTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCER 933
Query: 451 CE----CPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQ 505
CE CP G G++C D +EC + P +C NG C N++G + C+C G T G +
Sbjct: 934 CELDTACPRGLARIK-GVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGR 992
Query: 506 TCV-----------DVDECAE---GR----ASCTF-------RCHNT----AGSFRCTCP 536
C+ D DEC G+ A C C + CP
Sbjct: 993 VCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCP 1052
Query: 537 YGYAVAADG------VHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDS 589
G A G +DI+EC P +C + C N +GS+ C+C G+ A
Sbjct: 1053 RGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGF----ALDME 1108
Query: 590 ENACEDINECEEQEDLCSGGVCINTDGSFLCDC----DAGFEPSEDGTDC--IDR----- 638
E C DI+EC DLC G+C+NT GSF C+C ++GF ++ D +R
Sbjct: 1109 ERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLC 1168
Query: 639 RTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECE 698
R GTC + S +C+ +C +G +C
Sbjct: 1169 RGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTY---QCS 1225
Query: 699 LCPA-PGSPAR-----LDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLD--VFADVDE 750
P +P R +D C +N D AD+DE
Sbjct: 1226 CNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDE 1285
Query: 751 CAAIPGLC-------APGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCD-QLCHNTDG 800
C P +C PG +RC+C G+ + ++ C DV+EC + C C NT G
Sbjct: 1286 CENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKG 1345
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
S+ C C+ GY + + C DVDECE H C C N GS++CSC +G+ G C
Sbjct: 1346 SFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKC 1405
Query: 859 V 859
+
Sbjct: 1406 I 1406
Score = 313 bits (769), Expect = 2e-84
Identities = 193/574 (33%), Positives = 256/574 (44%), Gaps = 45/574 (7%)
Query: 85 DTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRL 143
D FQ C +G+ + H R DV+EC C QC+N G+F C CP GY L
Sbjct: 2145 DDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSN-GQCINTDGSFRCECPMGYNL 2203
Query: 144 TPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENV-CRDVDECSRPRPVC 202
+ C D DEC C +G C N IGS+ C C G+ + C D++EC++ +C
Sbjct: 2204 DYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLC 2263
Query: 203 RNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVC--RNGRCRNTVGSFRCEC 259
C N G+Y C C G+ + C D++EC EG C R C+N +G+F C C
Sbjct: 2264 AL-RCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCIC 2322
Query: 260 APGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVD 317
PG DG C D +EC P C N C N G Y C C G++ G C+D
Sbjct: 2323 PPGMARRPDGEGCVDENECRTKPGICE---NGRCVNIIGSYRCECNEGFQSSSSGTECLD 2379
Query: 318 RDE----CKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVC----VDERKELCYDE 368
+ + L +C RN C C G + +C + K++C
Sbjct: 2380 NRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKIC--P 2437
Query: 369 WEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRP---NLTQ 425
G R + EC C F C+ G
Sbjct: 2438 HGPGYTTDGRDID----ECKVMPNLCTNGQCINT----MGSFRCFCKVGYTTDISGTSCI 2489
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
DLDEC P C C NT+GS++C CP GYVL DG +C D DEC C C
Sbjct: 2490 DLDECSQSPKPC-NYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNC-QFLCV 2547
Query: 486 NTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAA 543
NT GG+ C+C PGFTQ C+D +EC C + C NT GSF C C G+++ A
Sbjct: 2548 NTLGGFTCKCPPGFTQH-HTACIDNNECGSQPLLCGGKGICQNTPGSFSCECQRGFSLDA 2606
Query: 544 DGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQE 603
G++C D+DEC R C H C+N++G Y C CP+GY + N C D NEC
Sbjct: 2607 TGLNCEDVDECDGNHR-CQHGCQNILGGYRCGCPQGYIQ----HYQWNQCVDENECSNP- 2660
Query: 604 DLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
+ C C NT GS+ C C +GF + + C D
Sbjct: 2661 NACGSASCYNTLGSYKCACPSGFSFDQFSSACHD 2694
Score = 279 bits (683), Expect = 4e-74
Identities = 188/538 (34%), Positives = 249/538 (46%), Gaps = 80/538 (14%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C G P+ N + I+EC P LC C +T ++C C GY +C+D
Sbjct: 2236 CNCNEGFEPGPMMN-CEDINECAQNPLLCAL-RCMNTFGSYECTCPIGYALREDQKMCKD 2293
Query: 110 VDECSWGRPPC--RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQR-ICDHGD 166
+DEC+ G C RGM C NL G F C CPPG P + C D +EC + IC++G
Sbjct: 2294 LDECAEGLHDCESRGM-MCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGR 2352
Query: 167 CRNTIGSYRCECKPGYTLRENVCRDVDE----CSRP--RPVCRNGTCE-NLPGAYLCHCD 219
C N IGSYRCEC G+ + +D C + +C+ + NL C CD
Sbjct: 2353 CVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCD 2412
Query: 220 DG-----------------FKA----GPN--NDCVDVNECREGGMVCRNGRCRNTVGSFR 256
G +K GP D D++EC+ +C NG+C NT+GSFR
Sbjct: 2413 GGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFR 2472
Query: 257 CECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRR 314
C C GYT G +C D+DEC + P PC N C NT G Y+CSC G+ L G+
Sbjct: 2473 CFCKVGYTTDISGTSCIDLDECSQSPKPC----NYICKNTEGSYQCSCPRGYVLQEDGKT 2528
Query: 315 CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC 374
C D DEC+ + C C N GG+ C+CP G+ TA C D E G
Sbjct: 2529 CKDLDECQTKQHNCQF-LCVNTLGGFTCKCPPGFTQHHTA----------CIDNNECG-- 2575
Query: 375 HRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG--MGRPNLT-QDLDECR 431
++P C +G C+ P S E CQ G + L +D+DEC
Sbjct: 2576 --------SQPLLCGGKGI-----CQNTPGSFSCE----CQRGFSLDATGLNCEDVDECD 2618
Query: 432 VRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGY 491
C G C N G +RC CP GY+ CVD +EC+ +P CG+ +C NT G Y
Sbjct: 2619 GNHR-CQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECS-NPNACGSASCYNTLGSY 2675
Query: 492 ECQCSPGFTQGP-DQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC 548
+C C GF+ C DV+EC+ + C + C NT G + C CP GY G HC
Sbjct: 2676 KCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQG-HC 2732
Score = 261 bits (640), Expect = 6e-69
Identities = 156/443 (35%), Positives = 205/443 (46%), Gaps = 68/443 (15%)
Query: 423 LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNG 482
L Q +D C+ ++C+ GRC+ T S+RCEC GY +G C+D DEC +P C NG
Sbjct: 490 LNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANG-DCIDVDECTSNP--CTNG 546
Query: 483 TCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASC-TFRCHNTAGSFRCTCPYGYA 540
C NT G Y C+C GF + P Q C+D+DEC + C RC N+ GSF+C C G+
Sbjct: 547 DCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNSDGSFQCICNAGFE 606
Query: 541 VAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECE 600
+ DG +C D DEC C N GS+ C C G+ AP + C D++EC
Sbjct: 607 LTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGF--VLAP--NGRYCTDVDEC- 661
Query: 601 EQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID-RRTGTCYRSLVSGRCEPEXXXX 659
+ +C G CIN++GSF CDC G DG C+D TCY + G C
Sbjct: 662 QTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVC------- 714
Query: 660 XXXXXXXXXXXXXXXXXXGHVTKAQCCC-TLGAAWGSECELCPAPGSPARLDLCTA-VNL 717
G VTK++CCC +G C+ CPA S LC++ V +
Sbjct: 715 -------------VRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGI 761
Query: 718 TPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCA-------PGRFRCVCGPG 770
T D++ECA P +CA G +RC C G
Sbjct: 762 TVDG------------------------RDINECALDPDICANGICENLRGSYRCNCNSG 797
Query: 771 YRP--AGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECER 827
Y P +G C D+DEC V CD LC NT GSY C C GY + C D++ECE
Sbjct: 798 YEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECES 857
Query: 828 DTHTCQQICSNTEGSYECSCEDG 850
+ C N GS+ C C G
Sbjct: 858 NP-CVNGACRNNLGSFNCECSPG 879
Score = 257 bits (629), Expect = 1e-67
Identities = 213/668 (31%), Positives = 279/668 (41%), Gaps = 119/668 (17%)
Query: 55 GEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS 114
G I +T + ID C LC G C T + ++C C+ GY+ D C DVDEC+
Sbjct: 481 GPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGD-CIDVDECT 539
Query: 115 WGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRI-CDHGDCRNTIGS 173
PC CVN PG++ C+C G++ TP+ C D+DEC + C +G C N+ GS
Sbjct: 540 --SNPCTN-GDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNSDGS 596
Query: 174 YRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-C 230
++C C G+ L + C D DEC+ +C NG C N G++ C C GF PN C
Sbjct: 597 FQCICNAGFELTTDGKNCVDHDECTTTN-MCLNGMCINEDGSFKCICKPGFVLAPNGRYC 655
Query: 231 VDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV---DEC--------D 279
DV+EC+ G +C NG C N+ GSFRC+C PG + DGR C D C
Sbjct: 656 TDVDECQTPG-ICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVC 714
Query: 280 ELPHP-CGRDGNPSCTNTNGGYECSC------------GAGWKLVGRRCVDRD--ECKEL 324
P P C N + G+ C G VG RD EC
Sbjct: 715 VRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALD 774
Query: 325 PYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYD-EWEAGRCHRARPLQLA 383
P +CA G C N G Y C C +G+ D + C+D + L + G C R P
Sbjct: 775 PDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLC-RNTP---G 830
Query: 384 RPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCV 443
C C G + E C +D++EC P CV G C
Sbjct: 831 SYSCTCPPGYVFRTETETC----------------------EDINECESNP--CVNGACR 866
Query: 444 NTDGSFRCECPDGYVLAPDGLSCVDA--DECAL---DPR--ICGNGT-----CSNTRG-- 489
N GSF CEC G L+ GL C+D+ C L D R + NG C T G
Sbjct: 867 NNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAA 926
Query: 490 -GYECQ-------CSPGFTQGPDQTCVDVDECAEGRASC-TFRCHNTAGSFRCTCPYGYA 540
G C+ C G + TC DV+EC C RC N+ GSF C CP G
Sbjct: 927 WGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLT 986
Query: 541 VAADGVHCRDI-----------DECVQ--EPRVCPHACENVVGS---------------- 571
+ G C DI DEC+ + AC VG+
Sbjct: 987 LDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKE 1046
Query: 572 YICKCPE--GYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPS 629
Y CP G+ +DINEC+ +C+ G C NT GSF C C++GF
Sbjct: 1047 YETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALD 1106
Query: 630 EDGTDCID 637
+ +C D
Sbjct: 1107 MEERNCTD 1114
Score = 252 bits (616), Expect = 5e-66
Identities = 173/505 (34%), Positives = 223/505 (44%), Gaps = 93/505 (18%)
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGR 287
N +D+ C+ +C NGRC TV S+RCEC GY A+G +C DVDEC +PC
Sbjct: 491 NQTIDI--CKHHANLCLNGRCIPTVSSYRCECNMGYKQDANG-DCIDVDECTS--NPCT- 544
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECP 345
N C NT G Y C C AG++ + C+D DEC + +C G C N +G + C C
Sbjct: 545 --NGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNSDGSFQCICN 602
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
AG+ CVD +DE + C +E ++ C+ P
Sbjct: 603 AGFELTTDGKNCVD------HDE--------CTTTNMCLNGMCINEDGSFKCICK--PGF 646
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
A R C D+DEC+ P +C+ G C+N++GSFRC+CP G + DG
Sbjct: 647 VLAPNGRYCT----------DVDECQT-PGICMNGHCINSEGSFRCDCPPGLAVGMDGRV 695
Query: 466 CVDADECALDPRICGNGTCSNTRGGY----ECQCS-PGFTQG-PDQTCV----------- 508
CVD + G C G EC C+ P + G P Q C
Sbjct: 696 CVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLC 755
Query: 509 -----------DVDECAEGRASCTFR-CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
D++ECA C C N GS+RC C GY A G +C DIDEC+
Sbjct: 756 SSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLV 815
Query: 557 EPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTD 615
+C + C N GSY C CP GY + CEDINECE C G C N
Sbjct: 816 NRLLCDNGLCRNTPGSYSCTCPPGY----VFRTETETCEDINECESNP--CVNGACRNNL 869
Query: 616 GSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXX 675
GSF C+C G + S G CID GTC+ ++ RCE
Sbjct: 870 GSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCE--------------------VN 909
Query: 676 XXGHVTKAQCCCTLGAAWGSECELC 700
G K++CC TLGAAWGS CE C
Sbjct: 910 INGATLKSECCATLGAAWGSPCERC 934
Score = 235 bits (574), Expect = 6e-61
Identities = 177/569 (31%), Positives = 244/569 (42%), Gaps = 79/569 (13%)
Query: 133 FECRCPPGYRLTPSLDECEDV---DECGD-------QRICDHGDCRNTIGS---YRCE-- 177
F C PG++ P ++C + CGD C G +T GS +C
Sbjct: 93 FHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVR 152
Query: 178 CKPGYTLRENVC---RDVDECSRPRPVCRNGTCEN----LPGAYLC-------HCDDGFK 223
C G T ++ C + +PVC NG C+N + C C+ ++
Sbjct: 153 CMNGGTCADDHCQCQKGYIGTYCGQPVCENG-CQNGGRCIAQPCACVYGFTGPQCERDYR 211
Query: 224 AGPNNDCVDVNECREG--GMVCRNGRCRNTVG---SFRCECAP--------GYTLTADGR 270
GP V+ C+ G+VC C T G CE P G+
Sbjct: 212 TGPCFTQVNNQMCQGQLTGIVCTKTLCCATTGRAWGHPCEMCPAQPQPCRRGFIPNIRTG 271
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVC 328
C+DVDEC +P C + GN C NT G +EC C AG K ++C D DEC +P +C
Sbjct: 272 ACQDVDECQAIPGIC-QGGN--CINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGIC 328
Query: 329 AGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECC 388
GEC N G Y C CP G+ + C+D+R +C+ GRC + P ++ + +CC
Sbjct: 329 ETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCC 388
Query: 389 CSEGAAW--GRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTD 446
C G W G E CP S E+ R+C G+ + G R T
Sbjct: 389 CEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGS-----------AGSRPGGTG 437
Query: 447 GSFRCECPDGYVLAPDGLSCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQ 505
G+ +G P G + P + G G + +G G T +Q
Sbjct: 438 GNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQG----PIITGLTI-LNQ 492
Query: 506 TCVDVDECAEGRASC-TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA 564
T +D C C RC T S+RC C GY A+G C D+DEC P C +
Sbjct: 493 T---IDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANG-DCIDVDECTSNP--CTNG 546
Query: 565 -CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCD 623
C N GSY CKC G++RT Q AC DI+EC + LC G C+N+DGSF C C+
Sbjct: 547 DCVNTPGSYYCKCHAGFQRTPTKQ----ACIDIDECIQNGVLCKNGRCVNSDGSFQCICN 602
Query: 624 AGFEPSEDGTDCIDRRTGTCYRSLVSGRC 652
AGFE + DG +C+D T ++G C
Sbjct: 603 AGFELTTDGKNCVDHDECTTTNMCLNGMC 631
Score = 215 bits (526), Expect = 4e-55
Identities = 140/469 (29%), Positives = 195/469 (41%), Gaps = 59/469 (12%)
Query: 47 TALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHL 106
T +C PG P +EC P +C+ G C + ++C C+ G++ ++
Sbjct: 2317 TFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTE 2376
Query: 107 CRDVDE----CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRIC 162
C D + + C+ + NL EC C G + C ++IC
Sbjct: 2377 CLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKIC 2436
Query: 163 DHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
HG PGYT RD+DEC +C NG C N G++ C C G+
Sbjct: 2437 PHG--------------PGYTTDG---RDIDECKVMPNLCTNGQCINTMGSFRCFCKVGY 2479
Query: 223 KAG-PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDEL 281
C+D++EC + C N C+NT GS++C C GY L DG+ C+D+DEC
Sbjct: 2480 TTDISGTSCIDLDECSQSPKPC-NYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTK 2538
Query: 282 PHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAG-GECRNFNGGY 340
H C C NT GG+ C C G+ C+D +EC P +C G G C+N G +
Sbjct: 2539 QHNC----QFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPLLCGGKGICQNTPGSF 2594
Query: 341 VCECPAGWRFDKTAAVCVDERKELCYDEWEAG-RCHRARPLQLARPECCCSEGAAWGRYC 399
CEC G+ D T C D DE + RC L C C +G
Sbjct: 2595 SCECQRGFSLDATGLNCED------VDECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQW 2648
Query: 400 ERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVL 459
+C D +EC P+ C C NT GS++C CP G+
Sbjct: 2649 NQCV----------------------DENECS-NPNACGSASCYNTLGSYKCACPSGFSF 2685
Query: 460 APDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV 508
+C D +EC+ C G CSNT GGY C C PG+ + CV
Sbjct: 2686 DQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPPGYYRVGQGHCV 2733
Score = 136 bits (329), Expect = 3e-31
Identities = 99/316 (31%), Positives = 129/316 (40%), Gaps = 37/316 (11%)
Query: 250 NTVGS-FRCECAPGYTLTADGRNCRDVDECDELPHPCGRDG---NPS-CTNTNGGYECSC 304
N GS F C PG+ G C V C + CG DG P+ CT ++G +C
Sbjct: 87 NVCGSRFHSYCCPGWKTLPGGNQCI-VPICR---NSCG-DGFCSRPNMCTCSSGQISSTC 141
Query: 305 GA-GWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCE--CPAGWRFDKTAAVCV--- 358
G+ + RC++ C + C G + G VCE C G R CV
Sbjct: 142 GSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNGGRCIAQPCACVYGF 201
Query: 359 -------DERKELCYDEWEAGRCH-RARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
D R C+ + C + + + CC + G AWG CE CPA
Sbjct: 202 TGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATTGRAWGHPCEMCPAQPQP-- 259
Query: 411 MRICQGGMG---RPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
C+ G R QD+DEC+ P +C GG C+NT GSF C CP G+ + C
Sbjct: 260 ---CRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCE 316
Query: 468 DADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVD--VDECAEG--RASCTF 522
D DEC++ P IC G CSNT G Y C C G+ D C+D C G C
Sbjct: 317 DIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQ 376
Query: 523 RCHNTAGSFRCTCPYG 538
+C C G
Sbjct: 377 ELPGRMTKMQCCCEPG 392
Score = 132 bits (320), Expect = 4e-30
Identities = 73/217 (33%), Positives = 97/217 (44%), Gaps = 10/217 (4%)
Query: 69 DECDIMPQLCK-PGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+EC P LC G C +TP F C C G+ D T C DVDEC G C+ C
Sbjct: 2572 NECGSQPLLCGGKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECD-GNHRCQH--GCQ 2628
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE- 186
N+ G + C CP GY ++C D +EC + C C NT+GSY+C C G++ +
Sbjct: 2629 NILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQF 2688
Query: 187 -NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN 245
+ C DV+ECS + C G C N G YLC C G+ CV +G + +
Sbjct: 2689 SSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKGQYLSLD 2747
Query: 246 GRC--RNTVGSFRC-ECAPGYTLTADGRNCRDVDECD 279
N + C EC D R R + E D
Sbjct: 2748 TEVDEENALSPEACYECKINGYPKKDSRQKRSIHEPD 2784
Score = 130 bits (315), Expect = 2e-29
Identities = 54/122 (44%), Positives = 71/122 (58%), Gaps = 9/122 (7%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHN 797
D+DEC +P LC G+ FRC C GY +G C D+DEC+ P PC+ +C N
Sbjct: 2448 DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKN 2507
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA 857
T+GSY C C GY L EDG C+D+DEC+ H CQ +C NT G + C C G+ + A
Sbjct: 2508 TEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTA 2567
Query: 858 CV 859
C+
Sbjct: 2568 CI 2569
Score = 129 bits (311), Expect = 5e-29
Identities = 99/308 (32%), Positives = 135/308 (43%), Gaps = 53/308 (17%)
Query: 424 TQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNG 482
++ + +C VR C+ GG C + C+C GY+ G + + C R C
Sbjct: 143 SKSIQQCSVR---CMNGGTCADD----HCQCQKGYIGTYCGQPVCE-NGCQNGGR-CIAQ 193
Query: 483 TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS---CTFR-CHNTAG---SFRCT- 534
C+ G QC + GP T V+ C +G+ + CT C T G C
Sbjct: 194 PCACVYGFTGPQCERDYRTGPCFTQVNNQMC-QGQLTGIVCTKTLCCATTGRAWGHPCEM 252
Query: 535 -------CPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAP 586
C G+ C+D+DEC P +C C N VGS+ C+CP G++++
Sbjct: 253 CPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETT 312
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS 646
Q CEDI+EC +C G C NT GS+ C C G+ S DG+ CID+RTG C+
Sbjct: 313 QK----CEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSG 368
Query: 647 LVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAW--GSECELCPAPG 704
LV+GRC E G +TK QCCC G W G+ E CP G
Sbjct: 369 LVNGRCAQE--------------------LPGRMTKMQCCCEPGRCWGIGTIPEACPVRG 408
Query: 705 SPARLDLC 712
S LC
Sbjct: 409 SEEYRRLC 416
Score = 109 bits (262), Expect = 4e-23
Identities = 64/191 (33%), Positives = 92/191 (48%), Gaps = 19/191 (9%)
Query: 7 DQSCAGAV-GVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNET 65
+Q C G + G+ TK LCC + G AWG PCE CP + P + G N T
Sbjct: 221 NQMCQGQLTGIVCTKTLCCATTGRAWGHPCEMCPAQPQPC-------RRGFIPNIRTGAC 273
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ 125
+ +DEC +P +C+ G C +T F+C C G++ T+ C D+DECS C +
Sbjct: 274 QDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICE-TGE 332
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECK-PGYTL 184
C N G++ C CP GY +T + D C DQR G C + + + RC + PG
Sbjct: 333 CSNTVGSYFCVCPRGY-VTST-----DGSRCIDQRT---GMCFSGLVNGRCAQELPGRMT 383
Query: 185 RENVCRDVDEC 195
+ C + C
Sbjct: 384 KMQCCCEPGRC 394
Score = 103 bits (246), Expect = 4e-21
Identities = 49/125 (39%), Positives = 65/125 (52%), Gaps = 11/125 (8%)
Query: 746 ADVDECAAIPGLC-------APGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCH 796
+DVDECA LC PG +RC C G+ PA + C D+DEC+ + C+
Sbjct: 1447 SDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVSGTCN 1506
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KR 854
N G + C+C GYELD G NC D+DEC + +C NT G YEC+C ++
Sbjct: 1507 NLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPT 1566
Query: 855 GDACV 859
G CV
Sbjct: 1567 GVGCV 1571
Score = 96.7 bits (230), Expect = 3e-19
Identities = 46/113 (40%), Positives = 55/113 (48%), Gaps = 9/113 (7%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNT 798
D+DEC C G F C C PG+ C D +EC +P C +C NT
Sbjct: 2531 DLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPLLCGGKGICQNT 2590
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
GS+ C C+ G+ LD G NC DVDEC+ H CQ C N G Y C C GY
Sbjct: 2591 PGSFSCECQRGFSLDATGLNCEDVDECD-GNHRCQHGCQNILGGYRCGCPQGY 2642
Score = 95.9 bits (228), Expect = 5e-19
Identities = 50/125 (40%), Positives = 64/125 (51%), Gaps = 12/125 (9%)
Query: 747 DVDECA-AIP---GLCAP--GRFRCVCGPGYRPAGEV-CADVDECAVRPPPCDQLCHNTD 799
D DEC+ P G C G F C C G+ P + C D++ECA P C C NT
Sbjct: 2212 DTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCALRCMNTF 2271
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ---QICSNTEGSYECSCEDGYEKR-- 854
GSY+C C GY L ED C+D+DEC H C+ +C N G++ C C G +R
Sbjct: 2272 GSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPD 2331
Query: 855 GDACV 859
G+ CV
Sbjct: 2332 GEGCV 2336
Score = 93.5 bits (222), Expect = 3e-18
Identities = 49/122 (40%), Positives = 62/122 (50%), Gaps = 9/122 (7%)
Query: 747 DVDECAAIP---GLC--APGRFRCVCGPGYRPA-GEVCADVDECA-VRPPPC-DQLCHNT 798
DVDEC P G C G + C+C PG+ C D+DEC+ C + C N
Sbjct: 1933 DVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNE 1992
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA 857
GS+ CLC GYEL DG NC D +EC +C C N EGS+ C C GYE + +
Sbjct: 1993 IGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN 2052
Query: 858 CV 859
C+
Sbjct: 2053 CI 2054
Score = 87.0 bits (206), Expect = 3e-16
Identities = 42/103 (40%), Positives = 53/103 (51%), Gaps = 5/103 (4%)
Query: 761 GRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDEDGA 817
G +RC C GY C D +EC+ P C C+NT GSY C C +G+ D+ +
Sbjct: 2632 GGYRCGCPQGYIQHYQWNQCVDENECS-NPNACGSASCYNTLGSYKCACPSGFSFDQFSS 2690
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
C DV+EC + C CSNTEG Y C C GY + G CV
Sbjct: 2691 ACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCV 2733
Score = 84.2 bits (199), Expect = 2e-15
Identities = 46/122 (37%), Positives = 58/122 (47%), Gaps = 13/122 (10%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAGEVCADVDECAVRPPPC--DQLCH 796
DVDEC C PG F+C C G+ G C D+DEC+ C + C
Sbjct: 1366 DVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCV 1425
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRG 855
NT GSY C C G+ DG C DVDEC + + C+ C N G+Y C CE G+
Sbjct: 1426 NTPGSYRCACSEGF--TGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPAS 1483
Query: 856 DA 857
D+
Sbjct: 1484 DS 1485
Score = 79.4 bits (187), Expect = 5e-14
Identities = 42/118 (35%), Positives = 58/118 (49%), Gaps = 12/118 (10%)
Query: 747 DVDECAAIPGLCAP------GRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQ---LC 795
D++ECA P LCA G + C C GY R ++C D+DECA C+ +C
Sbjct: 2252 DINECAQNPLLCALRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMC 2311
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE 852
N G++ C+C G DG C D +EC C+ C N GSY C C +G++
Sbjct: 2312 KNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQ 2369
Score = 78.6 bits (185), Expect = 9e-14
Identities = 43/118 (36%), Positives = 57/118 (48%), Gaps = 10/118 (8%)
Query: 748 VDECAAIPGLCAPGR-------FRCVCGPGYRP-AGEVCADVDECAVRPPPCDQLCHNTD 799
+D C LC GR +RC C GY+ A C DVDEC P C NT
Sbjct: 494 IDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTNGD-CVNTP 552
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
GSY C C G++ C D+DEC ++ C+ C N++GS++C C G+E D
Sbjct: 553 GSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNSDGSFQCICNAGFELTTD 610
Score = 77.8 bits (183), Expect = 2e-13
Identities = 45/125 (36%), Positives = 59/125 (47%), Gaps = 13/125 (10%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYRPAGEVCADVDECAVRPPPC-DQLCHNT 798
D +EC A+PG C+PG FRC+C PGY E C D++EC P C C NT
Sbjct: 2015 DTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTNT 2074
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICS-----NTEGSYECSCEDGYEK 853
G + CLC G+ L ++G C D + T+ CS NT + C + E
Sbjct: 2075 PGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEG 2134
Query: 854 RGDAC 858
GD C
Sbjct: 2135 WGDPC 2139
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/118 (36%), Positives = 55/118 (46%), Gaps = 14/118 (11%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYRPAG--EVCADVDECAVRPPPCDQ-LCH 796
DVDEC AIPG+C G F C C G++ + + C D+DEC++ P C+ C
Sbjct: 275 DVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECS 334
Query: 797 NTDGSYDCLCRTGYELDEDGANCRD--VDECERD--THTCQQICSNTEGSYECSCEDG 850
NT GSY C+C GY DG+ C D C C Q +C CE G
Sbjct: 335 NTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 392
Score = 71.3 bits (167), Expect = 1e-11
Identities = 36/86 (41%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 778 CADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-I 835
C DVDEC P C C NT GS++C C G++ E C D+DEC C+
Sbjct: 273 CQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGE 332
Query: 836 CSNTEGSYECSCEDGY--EKRGDACV 859
CSNT GSY C C GY G C+
Sbjct: 333 CSNTVGSYFCVCPRGYVTSTDGSRCI 358
Score = 68.9 bits (161), Expect = 7e-11
Identities = 41/115 (35%), Positives = 48/115 (41%), Gaps = 11/115 (9%)
Query: 747 DVDECAAIPGLCA--------PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCH 796
D +EC + P LC PG F C C G+ G C DVDEC C C
Sbjct: 2570 DNNECGSQPLLCGGKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHR-CQHGCQ 2628
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
N G Y C C GY C D +EC C NT GSY+C+C G+
Sbjct: 2629 NILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGF 2683
Score = 67.7 bits (158), Expect = 2e-10
Identities = 38/106 (35%), Positives = 55/106 (51%), Gaps = 10/106 (9%)
Query: 763 FRCVCG--PGYR---PAGEVCADVDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDG 816
F+ +CG PG+ G+ D+DEC P C + +C N GS+ C C TG+ ++
Sbjct: 1786 FKTICGNIPGFTFDIHTGKA-VDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLL 1844
Query: 817 ANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE-KRGDACV 859
C D+DEC + CQ+ C N+ GSY C C G++ ACV
Sbjct: 1845 LVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACV 1890
Score = 66.1 bits (154), Expect = 5e-10
Identities = 41/121 (33%), Positives = 56/121 (46%), Gaps = 14/121 (11%)
Query: 747 DVDECA----AIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPC-DQLCHN 797
D+DEC+ + G C PG F C+C GY G C D+DECA P C + LC N
Sbjct: 1490 DIDECSFQNICVSGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECA-DPINCVNGLCVN 1548
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA 857
T G Y+C C ++L+ G C D R + + +GS C+ E G +
Sbjct: 1549 TPGRYECNCPPDFQLNPTGVGCVD----NRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSS 1604
Query: 858 C 858
C
Sbjct: 1605 C 1605
Score = 64.1 bits (149), Expect = 2e-09
Identities = 35/99 (35%), Positives = 43/99 (43%), Gaps = 9/99 (9%)
Query: 761 GRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGA 817
G F C+C PG RP GE C D +EC +P C+ C N GSY C C G++ G
Sbjct: 2316 GTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGT 2375
Query: 818 NCRDVDECERDTHTCQQICSNTEGS------YECSCEDG 850
C D + Q IC S EC C+ G
Sbjct: 2376 ECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGG 2414
Score = 43.6 bits (98), Expect = 0.003
Identities = 20/49 (40%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYEK 853
CR G+ + C+DVDEC+ CQ C NT GS+EC C G+++
Sbjct: 260 CRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQ 308
Score = 40.7 bits (91), Expect = 0.022
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPC--EACPPRGSPAHTALC 50
CA + TK CCC G WG EACP RGS + LC
Sbjct: 374 CAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLC 416
>AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant
protein.
Length = 830
Score = 599 bits (1478), Expect = e-170
Identities = 273/647 (42%), Positives = 374/647 (57%), Gaps = 30/647 (4%)
Query: 6 EDQSCAGAVGVPQTKYLCCCS--VGHAWGAPCEACPPRGSPAHTALCG-EKPGEYINPVT 62
++Q+C G + TK +CCCS +G AW PCE CP + LCG ++PG I+ T
Sbjct: 137 DNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYT 196
Query: 63 NETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRG 122
IDEC +P +C+ G C + F+C C G+ +++ +C D+DEC G P C+
Sbjct: 197 GLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNG-PVCQR 255
Query: 123 MAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCECKPG 181
A+C+N G++ C C PGYR T S +C D +EC + IC HG C +T+GS+ C C G
Sbjct: 256 NAECINTAGSYRCDCKPGYRFT-STGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTG 314
Query: 182 YTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREG 239
+ ++ +C D++EC R C NGTC N G++ C C+ GF NNDC+DV+EC G
Sbjct: 315 FKTNDDQTMCLDINECERD--ACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASG 372
Query: 240 -GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
G +CRNG+C NTVGSF+C+C GY + DGR C D++EC P C +C N +G
Sbjct: 373 NGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPG---TCQNLDG 429
Query: 299 GYECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV 358
Y C C G+ L +C D DEC E P +CA G C N G + C CP G+ + C
Sbjct: 430 SYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQ 489
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCS-EGAAWGRYCERCPAPDSAEFMRICQGG 417
D R CY ++E G+C + ++ ECCC+ +G WG CE CP F +IC G
Sbjct: 490 DLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYG 549
Query: 418 ----MGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
+G + D+DEC+ PDVC G+C+NTDGS+RCECP GY+LA G CVD DEC+
Sbjct: 550 SGIIVGPDDSAVDMDECK-EPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECS 606
Query: 474 LDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRC 533
+ CGNGTC N GG+EC C GF GP TC D++ECA+ C FRC NT GS+ C
Sbjct: 607 VG-NPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYEC 665
Query: 534 TCPYGYAVAADGVHCRDIDECVQEPRVCPH---ACENVVGSYICKCPEGYRRTSAPQDSE 590
CP GY + D C+D DEC + C C+N++G+Y+C C GY+R D E
Sbjct: 666 KCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRR---PDGE 722
Query: 591 NACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C D NEC+ + +C G C+NT GS+ C+C+ GF S + +C+D
Sbjct: 723 -GCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLD 768
Score = 398 bits (981), Expect = e-110
Identities = 270/792 (34%), Positives = 353/792 (44%), Gaps = 116/792 (14%)
Query: 114 SWGRPPCRGMAQCVNLPGAFECRCP--PGYRLTPSLDECEDVDECGD-QRICDHGDCRNT 170
+WG P C M VN ++ CP G+R P ED+DEC + +C G C NT
Sbjct: 4 AWGTP-CE-MCPAVNT-SEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINT 60
Query: 171 IGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCD-DGFKAGPN 227
GS++C C GY L E+ VC DV+EC P +C GTC N G Y C C D +
Sbjct: 61 FGSFQCRCPTGYYLNEDTRVCDDVNECETPG-ICGPGTCYNTVGNYTCICPPDYMQVNGG 119
Query: 228 NDCVDVNE--CREGGMVCRNGRCRNTV--GSFRCECAPGYTLTADGRNCRDVDECDELPH 283
N+C+D+ C N C + + C Y + GR C++ P
Sbjct: 120 NNCMDMRRSLCYRN-YYADNQTCDGELLFNMTKKMCCCSYNI---GRAWNK--PCEQCPI 173
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCE 343
P + C + G+ G VD DEC+E+P VC G C N G + CE
Sbjct: 174 PSTDEFATLCGSQRPGFVIDIYTGLP------VDIDECREIPGVCENGVCINMVGSFRCE 227
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
CP G+ ++ VC D DE + G P+ EC + G+ RC
Sbjct: 228 CPVGFFYNDKLLVCED------IDECQNG------PVCQRNAECINTAGSY------RCD 269
Query: 404 APDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDG 463
F G+ N D +EC+ P++C G+C++T GSF C C G+ D
Sbjct: 270 CKPGYRFT-----STGQCN---DRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQ 321
Query: 464 LSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS-C-T 521
C+D +EC D CGNGTC NT G + C+C+ GF + C+DVDECA G + C
Sbjct: 322 TMCLDINECERDA--CGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRN 379
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC-PHACENVVGSYICKCPEGY 580
+C NT GSF+C C GY VA DG C DI+EC+ EPR C P C+N+ GSY C CP GY
Sbjct: 380 GQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGY 439
Query: 581 RRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRT 640
+ CEDI+EC E+ ++C+ G C NT+GSF C C GF S G C D R
Sbjct: 440 SLQN------EKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRM 493
Query: 641 GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTL-GAAWGSECE- 698
CY G+C H +K +CCC L G WG CE
Sbjct: 494 SYCYAKFEGGKCSSPKSR-------------------NH-SKQECCCALKGEGWGDPCEL 533
Query: 699 -----------LCP--------APGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXX 739
+CP S +D C ++
Sbjct: 534 CPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYI 593
Query: 740 XXLDVFADVDECAA-IP---GLCAP--GRFRCVCGPGYRPAGEV-CADVDECAVRPPPCD 792
+ D DEC+ P G C G F C C G+ P + C D++ECA P C
Sbjct: 594 LAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCA 653
Query: 793 QLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC---QQICSNTEGSYECSCED 849
C NT GSY+C C GY L ED C+D DECE H C Q C N G+Y C C
Sbjct: 654 FRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGP 713
Query: 850 GYEKR--GDACV 859
GY++R G+ CV
Sbjct: 714 GYQRRPDGEGCV 725
Score = 319 bits (784), Expect = 2e-86
Identities = 208/663 (31%), Positives = 298/663 (44%), Gaps = 82/663 (12%)
Query: 27 VGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDT 86
+G AWG PCE CP + + LC G NP+T + IDEC +P LC+ G C +T
Sbjct: 1 LGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINT 60
Query: 87 PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPS 146
FQC C GY + + +C DV+EC P G C N G + C CPP Y
Sbjct: 61 FGSFQCRCPTGYYLNEDTRVCDDVNECE--TPGICGPGTCYNTVGNYTCICPPDYMQVNG 118
Query: 147 LDECEDVDE--C-----GDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPR 199
+ C D+ C D + CD G+ + C C Y + + ++C P
Sbjct: 119 GNNCMDMRRSLCYRNYYADNQTCD-GELLFNMTKKMCCC--SYNIGRAWNKPCEQCPIPS 175
Query: 200 PVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCEC 259
C + ++ G VD++ECRE VC NG C N VGSFRCEC
Sbjct: 176 TDEFATLCGSQRPGFVIDIYTGLP-------VDIDECREIPGVCENGVCINMVGSFRCEC 228
Query: 260 APGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR-RCVDR 318
G+ C D+DEC P C R N C NT G Y C C G++ +C DR
Sbjct: 229 PVGFFYNDKLLVCEDIDECQNGP-VCQR--NAECINTAGSYRCDCKPGYRFTSTGQCNDR 285
Query: 319 DECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRAR 378
+EC+E+P +C+ G+C + G + C C G++ + +C+D E D G C
Sbjct: 286 NECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLD-INECERDACGNGTCRNT- 343
Query: 379 PLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRV-RPDVC 437
+ C C+ G F+ + N D+DEC ++C
Sbjct: 344 ---IGSFNCRCNHG-----------------FI------LSHNNDCIDVDECASGNGNLC 377
Query: 438 VGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSP 497
G+C+NT GSF+C+C +GY +APDG +CVD +EC L+PR C GTC N G Y C C P
Sbjct: 378 RNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPP 437
Query: 498 GFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYAVAADGVHCRDI--DEC 554
G++ ++ C D+DEC E C C NT GSF+C CP G+++++ G C+D+ C
Sbjct: 438 GYSL-QNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYC 496
Query: 555 VQ--EPRVCPHACENVVGSYICKCP---EGYRRTS--APQDSENACEDI----------- 596
E C C C EG+ P + + A I
Sbjct: 497 YAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGP 556
Query: 597 -NECEEQEDLCSGGVC-----INTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSG 650
+ + ++ VC INTDGS+ C+C G+ + G +C+D + +G
Sbjct: 557 DDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGNPCGNG 614
Query: 651 RCE 653
C+
Sbjct: 615 TCK 617
Score = 281 bits (689), Expect = 7e-75
Identities = 190/571 (33%), Positives = 258/571 (45%), Gaps = 77/571 (13%)
Query: 20 KYLCCCSVGHAWGAP-CEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLC 78
K L C + P C+ + A + C KPG Y T + +EC +P +C
Sbjct: 237 KLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPG-YRFTSTGQCNDRNECQEIPNIC 295
Query: 79 KPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCP 138
G C DT F C C G++ ++ +C D++EC R C G C N G+F CRC
Sbjct: 296 SHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECE--RDAC-GNGTCRNTIGSFNCRCN 352
Query: 139 PGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDE 194
G+ L+ + D C DVDEC G+ +C +G C NT+GS++C+C GY + + C D++E
Sbjct: 353 HGFILSHNND-CIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINE 411
Query: 195 CSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGS 254
C C GTC+NL G+Y C C G+ N C D++EC E +C G C NT GS
Sbjct: 412 CLLEPRKCAPGTCQNLDGSYRCICPPGYSL-QNEKCEDIDECVEEPEICALGTCSNTEGS 470
Query: 255 FRCECAPGYTLTA-----------------DGRNCRDVDECDELPHPC-----GRDGNPS 292
F+C C G++L++ +G C + C G
Sbjct: 471 FKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDP 530
Query: 293 C----TNTNGGYE--CSCGAGWKLVGR--RCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
C T + + C G+G +VG VD DECKE P VC G+C N +G Y CEC
Sbjct: 531 CELCPTEPDEAFRQICPYGSGI-IVGPDDSAVDMDECKE-PDVCKHGQCINTDGSYRCEC 588
Query: 345 PAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPA 404
P G+ CVD + + G C + EC C EG P
Sbjct: 589 PFGYIL--AGNECVDTDECSVGNPCGNGTCKNV----IGGFECTCEEGFE--------PG 634
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
P M C+ D++EC P +C RCVNT GS+ C+CP GYVL D
Sbjct: 635 P-----MMTCE----------DINECAQNPLLCAF-RCVNTYGSYECKCPVGYVLREDRR 678
Query: 465 SCVDADECALDPRICGNGT--CSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASC- 520
C D DEC C C N G Y C C PG+ + PD + CVD +EC C
Sbjct: 679 MCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICE 738
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRDI 551
RC NT GS+ C C G+ + + C D+
Sbjct: 739 NGRCLNTRGSYTCECNDGFTASPNQDECLDV 769
Score = 209 bits (510), Expect = 4e-53
Identities = 106/276 (38%), Positives = 142/276 (51%), Gaps = 13/276 (4%)
Query: 6 EDQSCAGAVGVPQTKYLCCCSV-GHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNE 64
E C+ +K CCC++ G WG PCE CP A +C G + P +
Sbjct: 501 EGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGP-DDS 559
Query: 65 TKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+DEC P +CK G C +T ++C C GY C D DECS G P C G
Sbjct: 560 AVDMDECK-EPDVCKHGQCINTDGSYRCECPFGYILAGNE--CVDTDECSVGNP-C-GNG 614
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
C N+ G FEC C G+ P + CED++EC + C NT GSY C+C GY L
Sbjct: 615 TCKNVIGGFECTCEEGFEPGPMMT-CEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVL 673
Query: 185 REN--VCRDVDECSRPRPVC--RNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREG 239
RE+ +C+D DEC + C + C+NL G Y+C C G++ P+ + CVD NEC+
Sbjct: 674 REDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTK 733
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV 275
+C NGRC NT GS+ CEC G+T + + C DV
Sbjct: 734 PGICENGRCLNTRGSYTCECNDGFTASPNQDECLDV 769
Score = 85.0 bits (201), Expect = 1e-15
Identities = 45/117 (38%), Positives = 57/117 (48%), Gaps = 12/117 (10%)
Query: 747 DVDECAAIPGLCA------PGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQL---C 795
D++ECA P LCA G + C C GY R +C D DEC C + C
Sbjct: 641 DINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMEC 700
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGY 851
N G+Y C+C GY+ DG C D +EC+ C+ C NT GSY C C DG+
Sbjct: 701 KNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGF 757
Score = 69.7 bits (163), Expect = 4e-11
Identities = 51/161 (31%), Positives = 66/161 (40%), Gaps = 33/161 (20%)
Query: 689 LGAAWGSECELCPAPGSPARLDLCT-AVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFAD 747
LG AWG+ CE+CPA + LC P + D
Sbjct: 1 LGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITV-------------------ILED 41
Query: 748 VDECAAIPGLCAPGR-------FRCVCGPGY--RPAGEVCADVDECAVRPPPCDQ-LCHN 797
+DEC +PGLC G+ F+C C GY VC DV+EC P C C+N
Sbjct: 42 IDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECET-PGICGPGTCYN 100
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDE--CERDTHTCQQIC 836
T G+Y C+C Y G NC D+ C R+ + Q C
Sbjct: 101 TVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTC 141
Score = 65.7 bits (153), Expect = 7e-10
Identities = 29/65 (44%), Positives = 36/65 (55%), Gaps = 3/65 (4%)
Query: 761 GRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGA 817
G + C+CGPGY RP GE C D +EC +P C+ C NT GSY C C G+ +
Sbjct: 705 GTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQD 764
Query: 818 NCRDV 822
C DV
Sbjct: 765 ECLDV 769
>AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein.
Length = 1365
Score = 450 bits (1110), Expect = e-126
Identities = 259/735 (35%), Positives = 348/735 (47%), Gaps = 91/735 (12%)
Query: 161 ICDHGDCRNTIGSYRCECKPGYTLR-ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCD 219
+C +G C T GS RCEC G+ L C DVDEC + P C G C N G+Y C C
Sbjct: 459 LCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEK-NP-CAGGECINNQGSYTCQCR 516
Query: 220 DGFKAG-PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC 278
G+++ +C D++EC + G +C NGRC NT GSF C C G+ +T DG+NC D+DEC
Sbjct: 517 AGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDEC 576
Query: 279 DELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNF 336
+ + C N C N +G ++C C G++L GR C D +EC E P +C G C N
Sbjct: 577 S-IRNMCL---NGMCINEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNGRCVNT 631
Query: 337 NGGYVCECPAGWRFDKTAAVCVDER-KELCYDEWEAGRCHRARPLQLARPECCC-SEGAA 394
+G Y CEC G VCVD + CY ++ G+C + + + ECCC S A
Sbjct: 632 DGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYA 691
Query: 395 WGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECP 454
+G C+ CPA +SAE+ +C G G + D++EC + PD+C G C N G+++C C
Sbjct: 692 FGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICN 751
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDEC 513
GY + G +CVD +EC L+ +C NG C NT G + C C GF PD +TC D+DEC
Sbjct: 752 SGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC 811
Query: 514 AEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE-NVVG-- 570
E C N+ GSF C C + C + + V CE N+ G
Sbjct: 812 -ESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGAT 870
Query: 571 --SYICK------------------CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV 610
S C C +GY R Q CEDI+ECE +C G+
Sbjct: 871 LKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQ-----CEDIDECEVFPGVCKNGL 925
Query: 611 CINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXX 670
C+NT GSF C C +G G C+D R TC+ C
Sbjct: 926 CVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEEC------------------ 967
Query: 671 XXXXXXXGHVTKAQCCCTLGAAWGS-ECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXX 729
G CCC++GAAWG+ ECE CP +P +LC
Sbjct: 968 --TLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCP---------------R 1010
Query: 730 XXXXXXXXXXXXLDVFADVDECAAIPGLCAPGR-------FRCVCGPGYRPAGEV--CAD 780
F D++EC IP LC G+ F+C C G+ E C D
Sbjct: 1011 GPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTD 1070
Query: 781 VDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD-EDGANCRDVDECERDTHTCQ-QICS 837
+DEC + P C + C NT G ++C C GYE NC D+DEC+RD C+ +C
Sbjct: 1071 IDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCH 1130
Query: 838 NTEGSYECSCEDGYE 852
NTEGSY C C G++
Sbjct: 1131 NTEGSYRCECPPGHQ 1145
Score = 390 bits (959), Expect = e-107
Identities = 234/680 (34%), Positives = 330/680 (48%), Gaps = 97/680 (14%)
Query: 19 TKYLCCC-SVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQL 77
TK CCC S +A+G PC+ CP + S + ALC PG +T+ I+EC + P +
Sbjct: 679 TKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPG-----MTSAGSDINECALDPDI 733
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRC 137
C G C + ++C C+ GYE D+T C D++EC C QC N PG+F C C
Sbjct: 734 CPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDN-GQCRNTPGSFVCTC 792
Query: 138 PPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL--RENVCRD---- 191
P G+ P L CED+DEC + C +G C+N+ GS+ CEC TL + +C +
Sbjct: 793 PKGFIYKPDLKTCEDIDEC-ESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKG 851
Query: 192 ------VD---ECSRPRPVCRNGTCENLPGAY-----LCH----CDDGFKAGPNNDCVDV 233
+D E + ++ C +L A+ LC C G+ C D+
Sbjct: 852 TCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDI 911
Query: 234 NECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV--DEC------DELPHP- 284
+EC VC+NG C NT GSF+C+C G TL A GR C D+ + C +E P
Sbjct: 912 DECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPI 971
Query: 285 CGRDGNPSCTNTNGG-----------------YE--CSCGAGW---KLVGRRCVDRD--E 320
GR +C + G YE C G G+ ++ + +D E
Sbjct: 972 AGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINE 1031
Query: 321 CKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKELCYDEWEAGRCHRARP 379
CK +P +C G+CRN G + C C +G+ D C D + + D G+C P
Sbjct: 1032 CKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT-P 1090
Query: 380 LQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG 439
EC C EG G M+ C D+DEC+ P +C G
Sbjct: 1091 GDF---ECKCDEGYESG-----------FMMMKNC----------MDIDECQRDPLLCRG 1126
Query: 440 GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGF 499
G C NT+GS+RCECP G+ L+P+ +C+D +EC L +C NG C N G Y+C C+PG+
Sbjct: 1127 GVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGY 1186
Query: 500 TQGPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEP 558
PD+ CVD+DEC+ C C N+ GS+ C+C G+A+ D C DIDEC P
Sbjct: 1187 HSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNP 1246
Query: 559 RVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGS 617
+C C N+ G Y C C +G+ A +D + C D+NEC+ ++C G C NT GS
Sbjct: 1247 NICDGGQCTNIPGEYRCLCYDGF---MASEDMK-TCVDVNECDLNPNICLSGTCENTKGS 1302
Query: 618 FLCDCDAGFEPSEDGTDCID 637
F+C CD G+ + T C D
Sbjct: 1303 FICHCDMGYSGKKGKTGCTD 1322
Score = 360 bits (885), Expect = 1e-98
Identities = 216/651 (33%), Positives = 304/651 (46%), Gaps = 71/651 (10%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C KPG + K I+EC+ P +C G C +T ++C C G +C D
Sbjct: 596 CICKPGFQLASDGRYCKDINECET-PGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVD 654
Query: 110 V---DECSWG--RPPC---------RGMAQCVNLPGAFECRCPP-------GYRLT---- 144
C G R C + C + AF C P Y+
Sbjct: 655 THMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG 714
Query: 145 PSLDEC-EDVDECG-DQRICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRP 200
P + D++EC D IC +G C N G+Y+C C GY + C D++EC
Sbjct: 715 PGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSL 774
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCRNGRCRNTVGSFRCEC 259
+C NG C N PG+++C C GF P+ C D++EC C NG C+N+ GSF CEC
Sbjct: 775 LCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSP--CINGVCKNSPGSFICEC 832
Query: 260 APGYTLTADGRNCRDVDE--CDE--LPHPC-----GRDGNPSCTNTNG---GYECS---- 303
+ TL C + + C + + C G C ++ G G C+
Sbjct: 833 SSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQV 892
Query: 304 ---CGAGW-KLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD 359
CG G+ ++ G +C D DEC+ P VC G C N G + C+CP+G D T +C+D
Sbjct: 893 DPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLD 952
Query: 360 ERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWG-RYCERCPAPDSAEFMRICQGGM 418
R E C+ +E C + CCCS GAAWG CE CP ++ E+ +C G
Sbjct: 953 IRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGP 1012
Query: 419 G--RPNLT------QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDAD 470
G +T +D++EC++ P +C G+C NT GSF+C C G+ L + +C D D
Sbjct: 1013 GFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDID 1072
Query: 471 ECALDPRICGNGTCSNTRGGYECQCSPGFTQG--PDQTCVDVDECAEGRASCTFR-CHNT 527
EC + P +CG G C NT G +EC+C G+ G + C+D+DEC C CHNT
Sbjct: 1073 ECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNT 1132
Query: 528 AGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAP 586
GS+RC CP G+ ++ + C DI+EC +CP+ C N++G Y C C GY T
Sbjct: 1133 EGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHST--- 1189
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+EC C C N++GS+ C C GF D C D
Sbjct: 1190 -PDRLFCVDIDECSIMNGGCE-TFCTNSEGSYECSCQPGFALMPDQRSCTD 1238
Score = 348 bits (856), Expect = 4e-95
Identities = 236/691 (34%), Positives = 310/691 (44%), Gaps = 100/691 (14%)
Query: 24 CCSVGHAWGAPC---EACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKP 80
C V PC E +GS +T C + G E + IDEC ++C
Sbjct: 488 CIDVDECEKNPCAGGECINNQGS--YTCQC--RAGYQSTLTRTECRDIDECLQNGRICNN 543
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
G C +T F C C+ G+ C D+DECS GM C+N G+F+C C PG
Sbjct: 544 GRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGM--CINEDGSFKCICKPG 601
Query: 141 YRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYT--LRENVCRDV------ 192
++L C+D++EC IC +G C NT GSYRCEC PG L VC D
Sbjct: 602 FQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTC 661
Query: 193 ------DECSRP-------RPVCRNGT-------CENLP----GAYLCHCDDGFKAGPNN 228
+C +P C T C+ P Y C G G +
Sbjct: 662 YGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG--PGMTS 719
Query: 229 DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRD 288
D+NEC +C NG C N G+++C C GY + + G+NC D++EC C
Sbjct: 720 AGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLC--- 776
Query: 289 GNPSCTNTNGGYECSCGAG--WKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPA 346
N C NT G + C+C G +K + C D DEC+ P C G C+N G ++CEC +
Sbjct: 777 DNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSP--CINGVCKNSPGSFICECSS 834
Query: 347 GWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPD 406
D T +C++ K C+ GRC + +CC S GAAWG C C
Sbjct: 835 ESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDP 894
Query: 407 SAEFMRICQGGMGRPNLTQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
IC G R TQ D+DEC V P VC G CVNT GSF+C+CP G L G
Sbjct: 895 ------ICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGR 948
Query: 465 SCVDA-----------DECAL--------DPRICGNGTCSNTRGGYECQ----------C 495
C+D +EC L D C G T EC C
Sbjct: 949 ICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELC 1008
Query: 496 --SPGF-----TQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYAVAADGVH 547
PGF T G D++EC + CT +C NT GSF+C C G+A+ ++ +
Sbjct: 1009 PRGPGFATKEITNG-KPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERN 1067
Query: 548 CRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLC 606
C DIDEC P +C C N G + CKC EGY S +N C DI+EC+ LC
Sbjct: 1068 CTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYE--SGFMMMKN-CMDIDECQRDPLLC 1124
Query: 607 SGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
GGVC NT+GS+ C+C G + S + + CID
Sbjct: 1125 RGGVCHNTEGSYRCECPPGHQLSPNISACID 1155
Score = 313 bits (769), Expect = 2e-84
Identities = 232/764 (30%), Positives = 307/764 (40%), Gaps = 82/764 (10%)
Query: 135 CRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYT---LRENVCRD 191
C CP G ++ PS + C + R + G C + C C+ GY + VC
Sbjct: 100 CTCPSG-QIAPSCGS-RSIQHC-NIRCMNGGSCSDD----HCLCQKGYIGTHCGQPVCES 152
Query: 192 VDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE--GGMVCRNGRCR 249
C C G C+ ++ GP + C+ G+VC C
Sbjct: 153 --GCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCC 210
Query: 250 NTVG---SFRCECAP--------GYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
TVG CE P G+ C+DVDEC +P C + GN C NT G
Sbjct: 211 ATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLC-QGGN--CINTVG 267
Query: 299 GYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
+EC C AG KL V ++C D DEC +P +C GGEC N Y C+CP G+
Sbjct: 268 SFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTR 327
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYC----ERCPAPDSAEFMR 412
C+D R CY GRC P + + +CCC G W E CP + +F +
Sbjct: 328 CIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNK 387
Query: 413 ICQGGM---GRPN-----LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
+C M GRP L V P G + P P L
Sbjct: 388 LCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSRE--PPRVL 445
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
D C L +C NG C T G C+C+ GF C+DVDEC E C
Sbjct: 446 PVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDEC-EKNPCAGGEC 504
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRT 583
N GS+ C C GY CRDIDEC+Q R+C + C N GS+ C C G+ T
Sbjct: 505 INNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVT 564
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRR---- 639
+D +N CED++EC + ++C G+CIN DGSF C C GF+ + DG C D
Sbjct: 565 ---RDGKN-CEDMDECSIR-NMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECET 619
Query: 640 -----TGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTL-GAAW 693
G C + S RCE G + QC L GA
Sbjct: 620 PGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVT 679
Query: 694 GSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAA 753
SEC C A A + C P +D++ECA
Sbjct: 680 KSEC--CCASTEYAFGEPCQP---CPAQNSAEYQALCSSGPGMTSAG-----SDINECAL 729
Query: 754 IPGLC-------APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ-LCHNTDGSYD 803
P +C G ++C+C GY G+ C D++EC + CD C NT GS+
Sbjct: 730 DPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFV 789
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSC 847
C C G+ D C D+DECE + +C N+ GS+ C C
Sbjct: 790 CTCPKGFIYKPDLKTCEDIDECE-SSPCINGVCKNSPGSFICEC 832
Score = 302 bits (742), Expect = 3e-81
Identities = 148/365 (40%), Positives = 191/365 (52%), Gaps = 16/365 (4%)
Query: 6 EDQSCAGAVGVPQTKYLCCCSVGHAWGAP-CEACPPRGSPAHTALCGEKPGEYINPVTNE 64
ED+ C + CCCSVG AWG CE CP R +P + LC PG +TN
Sbjct: 963 EDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNG 1022
Query: 65 T---KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
K I+EC ++P LC G C +T F+C CD G+ D+ C D+DEC C
Sbjct: 1023 KPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLC- 1081
Query: 122 GMAQCVNLPGAFECRCPPGYRL-TPSLDECEDVDEC-GDQRICDHGDCRNTIGSYRCECK 179
G QCVN PG FEC+C GY + C D+DEC D +C G C NT GSYRCEC
Sbjct: 1082 GRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECP 1141
Query: 180 PGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNEC 236
PG+ L N+ C D++EC +C NG C NL G Y C C+ G+ + P+ CVD++EC
Sbjct: 1142 PGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDEC 1201
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
C C N+ GS+ C C PG+ L D R+C D+DEC++ P+ C DG CTN
Sbjct: 1202 SIMNGGCET-FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNIC--DGG-QCTNI 1257
Query: 297 NGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTA 354
G Y C C G+ + CVD +EC P +C G C N G ++C C G+ K
Sbjct: 1258 PGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGK 1317
Query: 355 AVCVD 359
C D
Sbjct: 1318 TGCTD 1322
Score = 281 bits (689), Expect = 7e-75
Identities = 181/549 (32%), Positives = 255/549 (46%), Gaps = 86/549 (15%)
Query: 7 DQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETK 66
D C + K CC S+G AWG+PC C + P +CG+ Y + +
Sbjct: 859 DGRCEININGATLKSQCCSSLGAAWGSPCTLC--QVDP----ICGKG---YSRIKGTQCE 909
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDV-----------DECSW 115
IDEC++ P +CK G C +T F+C C G D T +C D+ +EC+
Sbjct: 910 DIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTL 969
Query: 116 ---GRPP-----CR-----GMAQCVNLP----GAFECRCP--PGY---RLTPSLDECEDV 153
GR C G +C P +E CP PG+ +T +D+
Sbjct: 970 PIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDI 1029
Query: 154 DECGD-QRICDHGDCRNTIGSYRCECKPGYTL--RENVCRDVDECSRPRPVCRNGTCENL 210
+EC +C HG CRNTIGS++C C G+ L E C D+DEC +C G C N
Sbjct: 1030 NECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 1089
Query: 211 PGAYLCHCDDGFKAG--PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTAD 268
PG + C CD+G+++G +C+D++EC+ ++CR G C NT GS+RCEC PG+ L+ +
Sbjct: 1090 PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPN 1149
Query: 269 GRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPY 326
C D++EC+ H C N C N G Y+C+C G+ R CVD DEC +
Sbjct: 1150 ISACIDINECELSAHLCP---NGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNG 1206
Query: 327 VCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPE 386
C C N G Y C C G+ A+ D+R DE E P
Sbjct: 1207 GCETF-CTNSEGSYECSCQPGF------ALMPDQRSCTDIDECEDN------------PN 1247
Query: 387 CCCSEGAAWGRYCERCPAPDSAEFMRICQGG-MGRPNLTQ--DLDECRVRPDVCVGGRCV 443
C G C P E+ +C G M ++ D++EC + P++C+ G C
Sbjct: 1248 ICD------GGQCTNIPG----EYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCE 1297
Query: 444 NTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQG 502
NT GSF C C GY C D +EC + CG + C+NT G ++C CSPG+ G
Sbjct: 1298 NTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI-G 1356
Query: 503 PDQTCVDVD 511
C D+D
Sbjct: 1357 DGIKCTDLD 1365
Score = 256 bits (626), Expect = 3e-67
Identities = 199/640 (31%), Positives = 271/640 (42%), Gaps = 89/640 (13%)
Query: 35 CEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGC 94
C+ R +P + +C G P + IDEC+ P C G C ++P F C C
Sbjct: 776 CDNGQCRNTPG-SFVCTCPKGFIYKPDLKTCEDIDECESSP--CINGVCKNSPGSFICEC 832
Query: 95 DHGYEHDNTSHLCRD----------VD-ECSWGRPPCRGMAQCVNLPGAFE------CR- 136
D T +C + +D C +QC + GA C+
Sbjct: 833 SSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQV 892
Query: 137 ---CPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTLREN--VCR 190
C GY +CED+DEC +C +G C NT GS++C+C G TL +C
Sbjct: 893 DPICGKGYSRIKGT-QCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICL 951
Query: 191 DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRN 250
D+ R TC C + + C V G C RN
Sbjct: 952 DI----------RLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAW-GTEECEECPMRN 1000
Query: 251 TVGSFR-CECAPGYT---LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
T C PG+ +T +D++EC +P C C NT G ++C C +
Sbjct: 1001 TPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHG---KCRNTIGSFKCRCDS 1057
Query: 307 GWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFD-KTAAVCVDERKE 363
G+ L R C D DEC+ P +C G+C N G + C+C G+ C+D
Sbjct: 1058 GFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMD---- 1113
Query: 364 LCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNL 423
DE C R PL C +EG+ RC P + PN+
Sbjct: 1114 --IDE-----CQRD-PLLCRGGVCHNTEGSY------RCECPPGHQLS---------PNI 1150
Query: 424 TQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGN 481
+ D++EC + +C GRCVN G ++C C GY PD L CVD DEC++ C
Sbjct: 1151 SACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCET 1210
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGY 539
C+N+ G YEC C PGF PDQ +C D+DEC + C +C N G +RC C G+
Sbjct: 1211 -FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGF 1269
Query: 540 AVAADGVHCRDIDECVQEPRVC-PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINE 598
+ D C D++EC P +C CEN GS+IC C GY + + + C DINE
Sbjct: 1270 MASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGY----SGKKGKTGCTDINE 1325
Query: 599 CEEQEDLCSG-GVCINTDGSFLCDCDAGFEPSEDGTDCID 637
CE C VC NT GSF C C G+ DG C D
Sbjct: 1326 CEIGAHNCGKHAVCTNTAGSFKCSCSPGW--IGDGIKCTD 1363
Score = 239 bits (585), Expect = 3e-62
Identities = 180/563 (31%), Positives = 246/563 (43%), Gaps = 65/563 (11%)
Query: 34 PCEACPPRGSPAHTALCGEKPGEYINPVTNETK--PI---DECDIMPQLCKPGTCHDTPT 88
P PP P P EY+ P + P+ D C ++ LC+ G C TP
Sbjct: 411 PVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPG 470
Query: 89 GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD 148
+C C+ G++ D C DVDEC + PC G +C+N G++ C+C GY+ T +
Sbjct: 471 SCRCECNKGFQLDLRGE-CIDVDECE--KNPCAG-GECINNQGSYTCQCRAGYQSTLTRT 526
Query: 149 ECEDVDEC-GDQRICDHGDCRNTIGSYRCECKPGY--TLRENVCRDVDECSRPRPVCRNG 205
EC D+DEC + RIC++G C NT GS+ C C G+ T C D+DECS R +C NG
Sbjct: 527 ECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECS-IRNMCLNG 585
Query: 206 TCENLPGAYLCHCDDGFK-AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYT 264
C N G++ C C GF+ A C D+NEC G +C NGRC NT GS+RCEC PG
Sbjct: 586 MCINEDGSFKCICKPGFQLASDGRYCKDINECETPG-ICMNGRCVNTDGSYRCECFPGLA 644
Query: 265 LTADGRNCRDVDECDELPHPC-GRDGNPSCTNTNGG----YECSCGAGWKLVGRRC--VD 317
+ DGR C D + C G C G EC C + G C
Sbjct: 645 VGLDGRVCVDT----HMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCP 700
Query: 318 RDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER---KELCYDEWEAGRC 374
E +C+ G G + EC +C + R K +C +E
Sbjct: 701 AQNSAEYQALCSSGPGMTSAGSDINECALDPDICPN-GICENLRGTYKCICNSGYEVDST 759
Query: 375 HRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC-QGGMGRPNL--TQDLDECR 431
+ + EC + C P F+ C +G + +P+L +D+DEC
Sbjct: 760 GKN---CVDINECVLNSLLCDNGQCRNTP----GSFVCTCPKGFIYKPDLKTCEDIDECE 812
Query: 432 VRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDAD-----ECALDPR--ICGNGT- 483
P C+ G C N+ GSF CEC L P C++ + +D R I NG
Sbjct: 813 SSP--CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGAT 870
Query: 484 ----CSNTRG---GYECQ-------CSPGFTQGPDQTCVDVDECAEGRASC-TFRCHNTA 528
C ++ G G C C G+++ C D+DEC C C NT
Sbjct: 871 LKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTR 930
Query: 529 GSFRCTCPYGYAVAADGVHCRDI 551
GSF+C CP G + A G C DI
Sbjct: 931 GSFKCQCPSGMTLDATGRICLDI 953
Score = 230 bits (563), Expect = 1e-59
Identities = 153/483 (31%), Positives = 211/483 (43%), Gaps = 46/483 (9%)
Query: 193 DECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTV 252
D C R +C+NG C PG+ C C+ GF+ +C+DV+EC + C G C N
Sbjct: 451 DYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKN--PCAGGECINNQ 508
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV- 311
GS+ C+C GY T CRD+DEC + C N C NT+G + C C AG+ +
Sbjct: 509 GSYTCQCRAGYQSTLTRTECRDIDECLQNGRIC---NNGRCINTDGSFHCVCNAGFHVTR 565
Query: 312 -GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWE 370
G+ C D DEC + +C G C N +G + C C G++ C D +E E
Sbjct: 566 DGKNCEDMDEC-SIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKD------INECE 618
Query: 371 A-GRCHRARPLQL-ARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLD 428
G C R + C C G A G C C GG R + L
Sbjct: 619 TPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCV---DTHMRSTCYGGYKRGQCIKPLF 675
Query: 429 ECRVRPDVCVGGRCVNTDGSF--RCE-CP-----DGYVLAPDGLSCV----DADECALDP 476
+ + C C +T+ +F C+ CP + L G D +ECALDP
Sbjct: 676 GAVTKSECC----CASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDP 731
Query: 477 RICGNGTCSNTRGGYECQCSPGF-TQGPDQTCVDVDECAEGRASC-TFRCHNTAGSFRCT 534
IC NG C N RG Y+C C+ G+ + CVD++EC C +C NT GSF CT
Sbjct: 732 DICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCT 791
Query: 535 CPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACE 594
CP G+ D C DIDEC P + C+N GS+IC+C S ++ C
Sbjct: 792 CPKGFIYKPDLKTCEDIDECESSPCI-NGVCKNSPGSFICECSS----ESTLDPTKTICI 846
Query: 595 DINECEEQEDLCSGGVCINTDGSFL---CDCDAGFEPSEDGTDC-IDRRTGTCYRSLVSG 650
+ + + + G IN +G+ L C G T C +D G Y +
Sbjct: 847 ETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGT 906
Query: 651 RCE 653
+CE
Sbjct: 907 QCE 909
Score = 140 bits (339), Expect = 2e-32
Identities = 113/358 (31%), Positives = 146/358 (40%), Gaps = 39/358 (10%)
Query: 210 LPGAYLCH-CDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGS-FRCECAPGYTLTA 267
L +Y H D +AG + R GG + N GS + C PG+
Sbjct: 16 LLASYTSHGADANLEAGNVKETRASRAKRRGGGGHDALKGPNVCGSRYNAYCCPGWKTLP 75
Query: 268 DGRNCRDVDECDELPHPCGRDG---NPS-CTNTNGGYECSCGA-GWKLVGRRCVDRDECK 322
G C V C H CG DG P+ CT +G SCG+ + RC++ C
Sbjct: 76 GGNQCI-VPICR---HSCG-DGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCS 130
Query: 323 ELPYVCAGGECRNFNGGYVCE--CPAGWRF--DKTAAVCVDERKELCYDEWEAGRCHRAR 378
+ +C G G VCE C G R A C ++ G C
Sbjct: 131 DDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVI 190
Query: 379 PLQLARPE----------CCCSEGAAWGRYCERCPAPDSAEFMRICQGGMG---RPNLTQ 425
Q+ + + CC + G AWG CE CPA C+ G R Q
Sbjct: 191 SNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHP-----CRRGFIPNIRTGACQ 245
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
D+DEC+ P +C GG C+NT GSF C+CP G+ L C D DEC+ P IC G C+
Sbjct: 246 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECT 305
Query: 486 NTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFRCHN----TAGSFRCTCPYG 538
NT Y C+C PGF PD T C+DV A RC N + +C C G
Sbjct: 306 NTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 363
Score = 128 bits (308), Expect = 1e-28
Identities = 99/330 (30%), Positives = 132/330 (40%), Gaps = 53/330 (16%)
Query: 411 MRICQGGMGRPNL-TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
M C G P+ ++ + C +R C+ G + D C C GY+ G ++
Sbjct: 99 MCTCPSGQIAPSCGSRSIQHCNIR---CMNGGSCSDD---HCLCQKGYIGTHCGQPVCES 152
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS---CTFR-CH 525
C R C+ T G QC + GP T + C +G+ S CT C
Sbjct: 153 G-CLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMC-QGQLSGIVCTKTLCC 210
Query: 526 NTAG---SFRCT--------CPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYI 573
T G C C G+ C+D+DEC P +C C N VGS+
Sbjct: 211 ATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFE 270
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGT 633
CKCP G++ Q CEDI+EC +C GG C NT S+ C C GF S DGT
Sbjct: 271 CKCPAGHKLNEVSQK----CEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGT 326
Query: 634 DCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAW 693
CID R G CY +L +GRC + +TK QCCC G W
Sbjct: 327 RCIDVRPGYCYTALTNGRCSNQLPQS--------------------ITKMQCCCDAGRCW 366
Query: 694 GSEC----ELCPAPGSPARLDLCTAVNLTP 719
E+CP + LC+ + P
Sbjct: 367 SPGVTVAPEMCPIRATEDFNKLCSVPMVIP 396
Score = 120 bits (289), Expect = 2e-26
Identities = 66/194 (34%), Positives = 93/194 (47%), Gaps = 19/194 (9%)
Query: 7 DQSCAGAV-GVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNET 65
+Q C G + G+ TK LCC +VG AWG PCE CP + P + G N T
Sbjct: 192 NQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPC-------RRGFIPNIRTGAC 244
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ 125
+ +DEC +P LC+ G C +T F+C C G++ + S C D+DECS C G +
Sbjct: 245 QDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEG-GE 303
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRN----TIGSYRCEC--- 178
C N ++ C+CPPG+ +P C DV +G C N +I +C C
Sbjct: 304 CTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 363
Query: 179 ---KPGYTLRENVC 189
PG T+ +C
Sbjct: 364 RCWSPGVTVAPEMC 377
Score = 100 bits (240), Expect = 2e-20
Identities = 44/115 (38%), Positives = 63/115 (54%), Gaps = 10/115 (8%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHN 797
D++EC LC GR ++C C PGY P C D+DEC++ C+ C N
Sbjct: 1155 DINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTN 1214
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGY 851
++GSY+C C+ G+ L D +C D+DECE + + C C+N G Y C C DG+
Sbjct: 1215 SEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGF 1269
Score = 97.5 bits (232), Expect = 2e-19
Identities = 46/124 (37%), Positives = 65/124 (52%), Gaps = 12/124 (9%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYRPAGEV--CADVDECAVRPPPC-DQLCH 796
D+DEC P +C PG +RC+C G+ + ++ C DV+EC + P C C
Sbjct: 1238 DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCE 1297
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKR 854
NT GS+ C C GY + C D++ECE H C +C+NT GS++CSC G+
Sbjct: 1298 NTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGD 1357
Query: 855 GDAC 858
G C
Sbjct: 1358 GIKC 1361
Score = 97.1 bits (231), Expect = 2e-19
Identities = 48/122 (39%), Positives = 61/122 (50%), Gaps = 12/122 (9%)
Query: 747 DVDECAAIPGLCA-------PGRFRCVCGPGYRPAGEV---CADVDECAVRPPPC-DQLC 795
D+DEC P LC PG F C C GY + C D+DEC P C +C
Sbjct: 1070 DIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVC 1129
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKR 854
HNT+GSY C C G++L + + C D++ECE H C C N G Y+C+C GY
Sbjct: 1130 HNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHST 1189
Query: 855 GD 856
D
Sbjct: 1190 PD 1191
Score = 94.3 bits (224), Expect = 2e-18
Identities = 45/115 (39%), Positives = 58/115 (50%), Gaps = 10/115 (8%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ-LCH 796
D+DEC P LC G +RC C PG++ P C D++EC + C C
Sbjct: 1113 DIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCV 1172
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
N G Y C C GY D C D+DEC C+ C+N+EGSYECSC+ G+
Sbjct: 1173 NLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGF 1227
Score = 91.5 bits (217), Expect = 1e-17
Identities = 44/118 (37%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 747 DVDECAAIP---GLCA--PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQ-LCHNT 798
DVDEC P G C G + C C GY+ C D+DEC C+ C NT
Sbjct: 490 DVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINT 549
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
DGS+ C+C G+ + DG NC D+DEC +C N +GS++C C+ G++ D
Sbjct: 550 DGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASD 607
Score = 85.8 bits (203), Expect = 6e-16
Identities = 38/94 (40%), Positives = 55/94 (58%), Gaps = 5/94 (5%)
Query: 765 CVCGPGYRPAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
C GPG AG +D++ECA+ P C +C N G+Y C+C +GYE+D G NC D++
Sbjct: 711 CSSGPGMTSAG---SDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDIN 767
Query: 824 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
EC ++ C C NT GS+ C+C G+ + D
Sbjct: 768 ECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPD 801
Score = 82.2 bits (194), Expect = 7e-15
Identities = 41/100 (41%), Positives = 51/100 (51%), Gaps = 5/100 (5%)
Query: 760 PGRFRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG RC C G++ GE C DVDEC P + C N GSY C CR GY+
Sbjct: 469 PGSCRCECNKGFQLDLRGE-CIDVDECEKNPCAGGE-CINNQGSYTCQCRAGYQSTLTRT 526
Query: 818 NCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD 856
CRD+DEC ++ C C NT+GS+ C C G+ D
Sbjct: 527 ECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRD 566
Score = 70.1 bits (164), Expect = 3e-11
Identities = 32/76 (42%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Query: 778 CADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ-QI 835
C DVDEC P C C NT GS++C C G++L+E C D+DEC C+
Sbjct: 244 CQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGE 303
Query: 836 CSNTEGSYECSCEDGY 851
C+NT SY C C G+
Sbjct: 304 CTNTVSSYFCKCPPGF 319
Score = 69.7 bits (163), Expect = 4e-11
Identities = 43/118 (36%), Positives = 53/118 (44%), Gaps = 14/118 (11%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ-LCH 796
DVDEC AIPGLC G F C C G++ + C D+DEC+ P C+ C
Sbjct: 246 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECT 305
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSN----TEGSYECSCEDG 850
NT SY C C G+ DG C DV T CSN + +C C+ G
Sbjct: 306 NTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 363
Score = 50.4 bits (115), Expect = 3e-05
Identities = 38/155 (24%), Positives = 52/155 (33%), Gaps = 12/155 (7%)
Query: 560 VCPHACENVVGSY--ICKCPEGYRRTSAPQDSENACE----DINECEEQEDLCSGGVCIN 613
+C H+C + S +C CP G S S C + C + LC G
Sbjct: 84 ICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGT 143
Query: 614 TDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXX 673
G +C+ +G C+ C +CE +
Sbjct: 144 HCGQPVCESGC-----LNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQ 198
Query: 674 XXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPAR 708
TK CC T+G AWG CE+CPA P R
Sbjct: 199 LSGIV-CTKTLCCATVGRAWGHPCEMCPAQPHPCR 232
Score = 43.6 bits (98), Expect = 0.003
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE 852
CR G+ + C+DVDEC+ CQ C NT GS+EC C G++
Sbjct: 231 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHK 278
>S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growth
factor-beta-binding protein-2 protein.
Length = 1821
Score = 445 bits (1097), Expect = e-124
Identities = 277/800 (34%), Positives = 373/800 (46%), Gaps = 94/800 (11%)
Query: 61 VTNETKPIDECDI-MPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPP 119
VT T ID C +C PGTC + P G++C C GY+ + C D +EC R P
Sbjct: 838 VTLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECL--RDP 895
Query: 120 CRGMAQCVNLPGAFECRCPPGYRLTPS--LDECEDVDECGDQRICDHGDCRNTIGSYRCE 177
C+G +C+N G++ C C PGY L S EC+D++EC +C G C NT GSY CE
Sbjct: 896 CKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCE 955
Query: 178 CKPGYTL-RENVCRDVDECSRPRPVCRNGTCENLPGAYLC-HCDDGFKAGPNNDCVDVNE 235
C GY + R+ C+D++EC P C +G C N PG+Y C C++G++ G + CVDVNE
Sbjct: 956 CDQGYIMVRKGHCQDINECRHPG-TCPDGRCVNSPGSYTCLACEEGYR-GQSGSCVDVNE 1013
Query: 236 CREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC-DELPHPCGRDGNPSCT 294
C G VC +G+C N GSFRC C GY +T+D + C+DVDEC P G C
Sbjct: 1014 CLTPG-VCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGL-----CL 1067
Query: 295 NTNGGYECS-CGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVC-ECPAGWRF 350
NT G + CS C G+ + G C D DEC P VC G C N G + C +C G+R
Sbjct: 1068 NTEGSFACSACENGYWVNEDGTACEDLDECA-FPGVCPSGVCTNTAGSFSCKDCDGGYRP 1126
Query: 351 DKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
C D DE E P+ C G C+ +
Sbjct: 1127 SPLGDSCED------VDECED-------------PQSSCLGGE-----CKNTVG----SY 1158
Query: 411 MRICQGGMGRPNLT--QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
+C G N T +D++EC G C+N+ GSF C C G+V A G SC D
Sbjct: 1159 QCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQD 1218
Query: 469 ADECAL-DPRICGNGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAE-GRASC-TFRC 524
DECA DP C G C NT G + C C GF P+ CVD+DEC + G C T++C
Sbjct: 1219 VDECATTDP--CVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKC 1276
Query: 525 HNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYR 581
N+ GS+RC C G+ +A +G C DIDEC + H C+N GS+ C C +G+
Sbjct: 1277 ENSPGSYRCVLGCQPGFHMAPNG-DCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFE 1335
Query: 582 RTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP--SEDGTDCIDRR 639
+ + D C D+NECE +C +C N +GSFLC C + E +++G C R
Sbjct: 1336 ISPSGWD----CVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEG-HCRPRG 1390
Query: 640 TGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECEL 699
G S + T+A+CCCT GA+WG C+L
Sbjct: 1391 AGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDL 1450
Query: 700 CPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAI-PGLC 758
CP+ S ++C + ++ D DEC PGLC
Sbjct: 1451 CPSEDSAEFSEICPS-------------GKGYIPVEGAWTFGQTMYTDADECVIFGPGLC 1497
Query: 759 APGR-------FRCVCGPG--YRPAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRT 808
GR + C+C PG Y + + C D DEC + C+ C NT+GS+ C C
Sbjct: 1498 PNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSP 1555
Query: 809 GYELDEDGANCRDVDECERD 828
LD C + D
Sbjct: 1556 PLTLDLSQQRCMNSTSSTED 1575
Score = 281 bits (689), Expect = 7e-75
Identities = 176/538 (32%), Positives = 240/538 (44%), Gaps = 54/538 (10%)
Query: 50 CGEKPGEYI-NPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR 108
C + G Y +P+ + + +DEC+ C G C +T +QC C G++ N + +C
Sbjct: 1117 CKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGT-VCE 1175
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCR 168
DV+EC G C +C+N G+F C C PG+ C+DVDEC C G C
Sbjct: 1176 DVNEC-MGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCV 1234
Query: 169 NTIGSYRCECKPGY--TLRENVCRDVDEC-SRPRPVCRNGTCENLPGAYLC--HCDDGFK 223
NT GS+ C C+ G+ + C D+DEC PVC CEN PG+Y C C GF
Sbjct: 1235 NTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFH 1294
Query: 224 AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPH 283
PN DC+D++EC M +G C NT GSFRC C G+ ++ G +C DV+EC+ +
Sbjct: 1295 MAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLA 1354
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGEC--RNFNGGYV 341
CG C N G + C C + D +E Y G C R G +
Sbjct: 1355 VCGA---ALCENVEGSFLCLCAS----------DLEE-----YDAQEGHCRPRGAGGQSM 1396
Query: 342 CECPAGWRFDKTAAVCVDERKELCYDEWEA-GRCHRARPLQLARPECCCSEGAAWGRYCE 400
E P G D A R + CY + C + ECCC++GA+WG C+
Sbjct: 1397 SEAPTG---DHAPA---PTRMD-CYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACD 1449
Query: 401 RCPAPDSAEFMRICQGGMG----------RPNLTQDLDECRV-RPDVCVGGRCVNTDGSF 449
CP+ DSAEF IC G G + D DEC + P +C GRC+NT +
Sbjct: 1450 LCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGY 1509
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG-PDQTCV 508
C C G+ C D DEC C NG C NT G + C CSP T Q C+
Sbjct: 1510 VCLCNPGFHYDASHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSPPLTLDLSQQRCM 1567
Query: 509 DVDECAEGRASCTFR---CHNTAGSFRCTCPY-GYAVAADGVHCRDIDECVQEPRVCP 562
+ E C + C+ P G+ C+D + Q+ +CP
Sbjct: 1568 NSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCP 1625
Score = 275 bits (674), Expect = 5e-73
Identities = 213/653 (32%), Positives = 302/653 (46%), Gaps = 85/653 (13%)
Query: 19 TKYLCCCS-VGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQL 77
TK +CCCS VG AWG+ CE CP G+ A +C G Y ++ + + + +L
Sbjct: 692 TKQICCCSRVGKAWGSECEKCPLPGTEAFREICPAGHG-YTYASSDIRLSMRKAE-EEEL 749
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC--VNLPGAFEC 135
+P + G G + D G P +G +Q V
Sbjct: 750 ARPPREQGQRSS---GALPGPAERQPLRVVTDT-WLEAGTIPDKGDSQAGQVTTSVTHAP 805
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCE-CKPGYTLRENVCRDVDE 194
G TP + E + + E ++++ D T+ + + C G T NVC
Sbjct: 806 AWVTGNATTPPMPE-QGIAEIQEEQVTPSTDVLVTLSTPGIDRCAAGAT---NVCGPGTC 861
Query: 195 CSRP---RPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNT 251
+ P R VC G + AY C D +N+C+ + C+ G C N
Sbjct: 862 VNLPDGYRCVCSPGYQLHPSQAY---CTD------DNECLR-DPCKGKGR-CIN-----R 905
Query: 252 VGSFRCECAPGYTLTADG--RNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
VGS+ C C PGYTL G + C+D++EC++ P C CTNT G Y C C G+
Sbjct: 906 VGSYSCFCYPGYTLATSGATQECQDINECEQ-PGVC---SGGQCTNTEGSYHCECDQGYI 961
Query: 310 LVGR-RCVDRDECKELPYVCAGGECRNFNGGYVC-ECPAGWRFDKTAAVCVDERKELCYD 367
+V + C D +EC+ P C G C N G Y C C G+R + V V+E C
Sbjct: 962 MVRKGHCQDINECRH-PGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNE----CL- 1015
Query: 368 EWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDL 427
G C A +C EG+ RC E +G QD+
Sbjct: 1016 --TPGVC--------AHGKCTNLEGSF------RCSCEQGYEVTSDEKG-------CQDV 1052
Query: 428 DECRVRPDVCVGGRCVNTDGSFRCE-CPDGYVLAPDGLSCVDADECALDPRICGNGTCSN 486
DEC R C G C+NT+GSF C C +GY + DG +C D DECA P +C +G C+N
Sbjct: 1053 DECASRAS-CPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVCPSGVCTN 1110
Query: 487 TRGGYECQ-CSPGFTQGP-DQTCVDVDECAEGRASCT-FRCHNTAGSFRCTCPYGYAVAA 543
T G + C+ C G+ P +C DVDEC + ++SC C NT GS++C CP G+ + A
Sbjct: 1111 TAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQL-A 1169
Query: 544 DGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQ 602
+G C D++EC+ E PH C N GS+ C C G+ SA + +C+D++EC
Sbjct: 1170 NGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGF--VSA--EGGTSCQDVDEC-AT 1224
Query: 603 EDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSG--RCE 653
D C GG C+NT+GSF C C+ GF+PS + +C+D Y V G +CE
Sbjct: 1225 TDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCE 1277
Score = 273 bits (669), Expect = 2e-72
Identities = 206/676 (30%), Positives = 273/676 (40%), Gaps = 71/676 (10%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
++EC + P +C G C + F+C C+ GYE + C+DVDEC+ R C C+
Sbjct: 1011 VNEC-LTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECA-SRASCP-TGLCL 1067
Query: 128 NLPGAFECR-CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRC-ECKPGYTLR 185
N G+F C C GY + CED+DEC +C G C NT GS+ C +C GY
Sbjct: 1068 NTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPS 1127
Query: 186 E--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC 243
+ C DVDEC P+ C G C+N G+Y C C GF+ C DVNEC
Sbjct: 1128 PLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCA 1187
Query: 244 RNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS 303
+G C N+ GSF C CAPG+ G +C+DVDEC PC C NT G + C
Sbjct: 1188 PHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDEC-ATTDPC---VGGHCVNTEGSFNCL 1243
Query: 304 CGAGWK--LVGRRCVDRDECKEL-PYVCAGGECRNFNGGYVC--ECPAGWRFDKTAAVCV 358
C G++ CVD DEC++ VC +C N G Y C C G+ C+
Sbjct: 1244 CETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGD-CI 1302
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
D + C ++ G H C C +G C + E M G
Sbjct: 1303 D--IDECANDTMCG-SHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAA 1359
Query: 419 GRPNL--------TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDG-YVLAPDGLSCVDA 469
N+ DL+E + C R G E P G + AP + C
Sbjct: 1360 LCENVEGSFLCLCASDLEEYDAQEGHC---RPRGAGGQSMSEAPTGDHAPAPTRMDCYSG 1416
Query: 470 DECALDPRICGNGTCSNTRG----GYECQCSPGFTQGPDQTCVDVDEC-AEGRASCTFRC 524
+ G+ CS+ G EC C+ G + G C D C +E A + C
Sbjct: 1417 QK--------GHAPCSSVLGRNTTQAECCCTQGASWG--DAC---DLCPSEDSAEFSEIC 1463
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECV-QEPRVCPHA-CENVVGSYICKCPEGYRR 582
+ G P A D DECV P +CP+ C N V Y+C C G+
Sbjct: 1464 PSGKGYI----PVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHY 1519
Query: 583 TSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGT 642
+ S CED +EC Q+ C G C+NT+GSF C C +D
Sbjct: 1520 DA----SHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSPPL--------TLDLSQQR 1565
Query: 643 CYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGH-VTKAQCCCTLGAAWGSECELCP 701
C S S P+ GH T +CCC G AW +C LCP
Sbjct: 1566 CMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCP 1625
Query: 702 APGSPARLDLCTAVNL 717
S LC +
Sbjct: 1626 PRSSEVYAQLCNVARI 1641
Score = 225 bits (550), Expect = 5e-58
Identities = 154/463 (33%), Positives = 200/463 (43%), Gaps = 46/463 (9%)
Query: 424 TQDLDECRV-RPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRIC-GN 481
T +D C +VC G CVN +RC C GY L P C D +EC DP C G
Sbjct: 842 TPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDP--CKGK 899
Query: 482 GTCSNTRGGYECQCSPGFT---QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYG 538
G C N G Y C C PG+T G Q C D++EC + +C NT GS+ C C G
Sbjct: 900 GRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQG 959
Query: 539 YAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYIC-KCPEGYRRTSAPQDSENACEDI 596
Y + G HC+DI+EC + P CP C N GSY C C EGYR S +C D+
Sbjct: 960 YIMVRKG-HCQDINEC-RHPGTCPDGRCVNSPGSYTCLACEEGYRGQSG------SCVDV 1011
Query: 597 NECEEQEDLCSGGVCINTDGSFLCDCDAGFEPS------EDGTDCIDRR---TGTCYRSL 647
NEC +C+ G C N +GSF C C+ G+E + +D +C R TG C +
Sbjct: 1012 NECLTP-GVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTE 1070
Query: 648 VSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECE--LCPAP-- 703
S C G C T G+ +C+ P+P
Sbjct: 1071 GSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLG 1130
Query: 704 GSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLD--VFADVDEC-----AAIPG 756
S +D C + + V DV+EC A G
Sbjct: 1131 DSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHG 1190
Query: 757 LC--APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
C + G F C+C PG+ A G C DVDECA P C NT+GS++CLC TG++
Sbjct: 1191 ECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQP 1250
Query: 813 DEDGANCRDVDECE--RDTHTCQQICSNTEGSYEC--SCEDGY 851
+ C D+DECE D C N+ GSY C C+ G+
Sbjct: 1251 SPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGF 1293
Score = 183 bits (446), Expect = 2e-45
Identities = 133/418 (31%), Positives = 172/418 (41%), Gaps = 37/418 (8%)
Query: 464 LSCVDADECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCT 521
LS D CA +CG GTC N GY C CSPG+ P Q C D +EC
Sbjct: 840 LSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGK 899
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGV--HCRDIDECVQEPRVCPHA-CENVVGSYICKCPE 578
RC N GS+ C C GY +A G C+DI+EC ++P VC C N GSY C+C +
Sbjct: 900 GRCINRVGSYSCFCYPGYTLATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECDQ 958
Query: 579 GYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC-DCDAGFEPSE----DGT 633
GY + C+DINEC C G C+N+ GS+ C C+ G+ D
Sbjct: 959 GYIMVR-----KGHCQDINECRHP-GTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVN 1012
Query: 634 DCIDRRT---GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLG 690
+C+ G C S RC E T C T G
Sbjct: 1013 ECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPT-GLCLNTEG 1071
Query: 691 AAWGSECE---LCPAPGSPAR-LDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXL---D 743
+ S CE G+ LD C + P D
Sbjct: 1072 SFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGD 1131
Query: 744 VFADVDEC-----AAIPGLC--APGRFRCVCGPGYRPA-GEVCADVDECAVRPPPCDQ-L 794
DVDEC + + G C G ++C+C G++ A G VC DV+EC
Sbjct: 1132 SCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGE 1191
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
C N+ GS+ CLC G+ E G +C+DVDEC C NTEGS+ C CE G++
Sbjct: 1192 CLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQ 1249
Score = 96.7 bits (230), Expect = 3e-19
Identities = 53/125 (42%), Positives = 67/125 (53%), Gaps = 14/125 (11%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHN 797
DV+EC PG+CA G+ FRC C GY + C DVDECA R LC N
Sbjct: 1010 DVNECLT-PGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLN 1068
Query: 798 TDGSYDC-LCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC-SCEDGYEKR- 854
T+GS+ C C GY ++EDG C D+DEC +C+NT GS+ C C+ GY
Sbjct: 1069 TEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSP 1128
Query: 855 -GDAC 858
GD+C
Sbjct: 1129 LGDSC 1133
Score = 92.3 bits (219), Expect = 7e-18
Identities = 51/124 (41%), Positives = 66/124 (53%), Gaps = 14/124 (11%)
Query: 747 DVDECAAIPGLC-------APGRFRCV-CGPGYRPAGEVCADVDECAVRPPPCDQ-LCHN 797
D++EC PG C +PG + C+ C GYR C DV+EC + P C C N
Sbjct: 970 DINECRH-PGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNEC-LTPGVCAHGKCTN 1027
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGY--EKR 854
+GS+ C C GYE+ D C+DVDEC +C NTEGS+ CS CE+GY +
Sbjct: 1028 LEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNED 1087
Query: 855 GDAC 858
G AC
Sbjct: 1088 GTAC 1091
Score = 87.4 bits (207), Expect = 2e-16
Identities = 52/149 (34%), Positives = 69/149 (46%), Gaps = 13/149 (8%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVT-----NE 64
C+ +G T+ CCC+ G +WG C+ CP S + +C G YI PV +
Sbjct: 1423 CSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKG-YI-PVEGAWTFGQ 1480
Query: 65 T--KPIDECDIM-PQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
T DEC I P LC G C +T G+ C C+ G+ +D + C D DEC C
Sbjct: 1481 TMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQ--DLACE 1538
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDEC 150
+CVN G+F C C P L S C
Sbjct: 1539 N-GECVNTEGSFHCFCSPPLTLDLSQQRC 1566
Score = 87.0 bits (206), Expect = 3e-16
Identities = 47/119 (39%), Positives = 65/119 (54%), Gaps = 14/119 (11%)
Query: 747 DVDECAA----IPGLCA--PGRFRCVCGPGYRPAGE--VCADVDECA-VRPPPCDQ-LCH 796
DVDECA + G C G F C+C G++P+ E C D+DEC P C C
Sbjct: 1218 DVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCE 1277
Query: 797 NTDGSYDCL--CRTGYELDEDGANCRDVDECERDTHT-CQQICSNTEGSYECSCEDGYE 852
N+ GSY C+ C+ G+ + +G +C D+DEC DT C NT+GS+ C C+ G+E
Sbjct: 1278 NSPGSYRCVLGCQPGFHMAPNG-DCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFE 1335
Score = 85.8 bits (203), Expect = 6e-16
Identities = 65/193 (33%), Positives = 83/193 (43%), Gaps = 18/193 (9%)
Query: 246 GRCR-NTVGSFRCECA-PGYTLTADGRNCRDVDEC--DELPHPCG-RDGNPSCTNTNGGY 300
GRC NTV +CA P LT C V L PC R +P N G
Sbjct: 552 GRCYLNTVNG---QCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIEN--GQL 606
Query: 301 ECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
EC G +L C D +EC L +C EC N G Y+C C G D + + CV +
Sbjct: 607 ECPQGYK-RLNLTHCQDINECLTLG-LCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSD 664
Query: 361 R-----KELCYDEWEAGRCHRARPLQLARPECCCSE-GAAWGRYCERCPAPDSAEFMRIC 414
+ + LCY G C ++ + CCCS G AWG CE+CP P + F IC
Sbjct: 665 KAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREIC 724
Query: 415 QGGMGRPNLTQDL 427
G G + D+
Sbjct: 725 PAGHGYTYASSDI 737
Score = 85.8 bits (203), Expect = 6e-16
Identities = 44/102 (43%), Positives = 57/102 (55%), Gaps = 9/102 (8%)
Query: 759 APGRFRCV--CGPGYR--PAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYEL 812
+PG +RCV C PG+ P G+ C D+DECA C C NTDGS+ CLC G+E+
Sbjct: 1279 SPGSYRCVLGCQPGFHMAPNGD-CIDIDECA-NDTMCGSHGFCDNTDGSFRCLCDQGFEI 1336
Query: 813 DEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEK 853
G +C DV+ECE C +C N EGS+ C C E+
Sbjct: 1337 SPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEE 1378
Score = 85.4 bits (202), Expect = 8e-16
Identities = 53/159 (33%), Positives = 71/159 (44%), Gaps = 32/159 (20%)
Query: 562 PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCD 621
P V+ + +CP+GY+R + C+DINEC LC C+NT GS+LC
Sbjct: 594 PRPASPVIENGQLECPQGYKRLNLTH-----CQDINECLTL-GLCKDAECVNTRGSYLCT 647
Query: 622 CDAGFEPSEDGTDCIDRRT-----GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXX 676
C G + C+ + G CYRSL G C
Sbjct: 648 CRPGLMLDPSRSRCVSDKAISMLQGLCYRSLGPGTC--------------------TLPL 687
Query: 677 XGHVTKAQCCCT-LGAAWGSECELCPAPGSPARLDLCTA 714
+TK CCC+ +G AWGSECE CP PG+ A ++C A
Sbjct: 688 AQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREICPA 726
Score = 84.2 bits (199), Expect = 2e-15
Identities = 54/125 (43%), Positives = 63/125 (50%), Gaps = 14/125 (11%)
Query: 747 DVDECAA---IP-GLC--APGRFRC-VCGPGY--RPAGEVCADVDECAVRPPPCDQ-LCH 796
DVDECA+ P GLC G F C C GY G C D+DECA P C +C
Sbjct: 1051 DVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVCPSGVCT 1109
Query: 797 NTDGSYDCL-CRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYE-K 853
NT GS+ C C GY G +C DVDECE +C C NT GSY+C C G++
Sbjct: 1110 NTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLA 1169
Query: 854 RGDAC 858
G C
Sbjct: 1170 NGTVC 1174
Score = 78.6 bits (185), Expect = 9e-14
Identities = 43/106 (40%), Positives = 59/106 (55%), Gaps = 10/106 (9%)
Query: 761 GRFRCVCGPGYR----PAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 815
G + C C PGY A + C D++EC +P C C NT+GSY C C GY +
Sbjct: 907 GSYSCFCYPGYTLATSGATQECQDINECE-QPGVCSGGQCTNTEGSYHCECDQGYIMVRK 965
Query: 816 GANCRDVDECERDTHTCQQ-ICSNTEGSYEC-SCEDGYEKRGDACV 859
G +C+D++EC R TC C N+ GSY C +CE+GY + +CV
Sbjct: 966 G-HCQDINEC-RHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCV 1009
Score = 70.1 bits (164), Expect = 3e-11
Identities = 31/75 (41%), Positives = 42/75 (56%), Gaps = 4/75 (5%)
Query: 202 CRNGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECRE---GGMVCRNGRCRNTVGSFRC 257
C NG C + Y C C +GF+ + CVDVNEC + ++C +G C NT GS+RC
Sbjct: 1743 CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC 1802
Query: 258 ECAPGYTLTADGRNC 272
C+PGY A +C
Sbjct: 1803 HCSPGYVAEAGPPHC 1817
Score = 67.7 bits (158), Expect = 2e-10
Identities = 37/93 (39%), Positives = 43/93 (46%), Gaps = 6/93 (6%)
Query: 461 PDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAE--GR 517
P G + A+EC + C NG C R GY C C GF CVDV+EC + G
Sbjct: 1726 PAGFEGLQAEECGI-LNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGP 1784
Query: 518 ASCTFR--CHNTAGSFRCTCPYGYAVAADGVHC 548
A C NT GS+RC C GY A HC
Sbjct: 1785 AVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHC 1817
Score = 65.3 bits (152), Expect = 9e-10
Identities = 48/134 (35%), Positives = 63/134 (47%), Gaps = 16/134 (11%)
Query: 365 CYDEWEAGRCHRARPL-QLARPECCC-SEGAAWG-RYCERCPAPDSAEFMRI----CQGG 417
CY G+C A PL +L E CC S GA WG C CP ++ + C G
Sbjct: 554 CYLNTVNGQC--ANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQG 611
Query: 418 MGRPNLT--QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
R NLT QD++EC + +C CVNT GS+ C C G +L P CV ++
Sbjct: 612 YKRLNLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISML 670
Query: 476 PRIC----GNGTCS 485
+C G GTC+
Sbjct: 671 QGLCYRSLGPGTCT 684
Score = 65.3 bits (152), Expect = 9e-10
Identities = 29/75 (38%), Positives = 42/75 (56%), Gaps = 4/75 (5%)
Query: 428 DECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC--ALDPRI-CGNGTC 484
+EC + + C GRCV + C+C +G+ L ++CVD +EC P + C +G C
Sbjct: 1735 EECGIL-NGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYC 1793
Query: 485 SNTRGGYECQCSPGF 499
NT G Y C CSPG+
Sbjct: 1794 ENTEGSYRCHCSPGY 1808
Score = 63.7 bits (148), Expect = 3e-09
Identities = 31/80 (38%), Positives = 43/80 (53%), Gaps = 7/80 (8%)
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTL--RENVCRDVDEC---SRPRPVCRNGTCE 208
+ECG C++G C Y C+C G+ L C DV+EC + P +C +G CE
Sbjct: 1735 EECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCE 1794
Query: 209 NLPGAYLCHCDDGF--KAGP 226
N G+Y CHC G+ +AGP
Sbjct: 1795 NTEGSYRCHCSPGYVAEAGP 1814
Score = 62.1 bits (144), Expect = 8e-09
Identities = 27/62 (43%), Positives = 35/62 (56%), Gaps = 4/62 (6%)
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQR----ICDHGDCRNTIGSYRCECKP 180
+CV + + C C G++L + C DV+EC D +C HG C NT GSYRC C P
Sbjct: 1747 RCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSP 1806
Query: 181 GY 182
GY
Sbjct: 1807 GY 1808
Score = 61.3 bits (142), Expect = 1e-08
Identities = 26/66 (39%), Positives = 33/66 (50%)
Query: 243 CRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC 302
C NGRC + C+C G+ L A C DV+ECD+L P + C NT G Y C
Sbjct: 1743 CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC 1802
Query: 303 SCGAGW 308
C G+
Sbjct: 1803 HCSPGY 1808
Score = 56.8 bits (131), Expect = 3e-07
Identities = 35/92 (38%), Positives = 40/92 (43%), Gaps = 10/92 (10%)
Query: 765 CVCGPGYRPA------GEVC-ADVDECAVRPPP-CDQ-LCHNTDGSYDCLCRTGYELDED 815
C G GY P G+ D DEC + P C C NT Y CLC G+ D
Sbjct: 1463 CPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDAS 1522
Query: 816 GANCRDVDECERDTHTCQQICSNTEGSYECSC 847
C D DEC+ D C NTEGS+ C C
Sbjct: 1523 HKKCEDHDECQ-DLACENGECVNTEGSFHCFC 1553
Score = 53.6 bits (123), Expect = 3e-06
Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Query: 134 ECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVD 193
+ CP GY+ +L C+D++EC +C +C NT GSY C C+PG L + R V
Sbjct: 605 QLECPQGYKRL-NLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVS 663
Query: 194 E 194
+
Sbjct: 664 D 664
Score = 52.4 bits (120), Expect = 7e-06
Identities = 39/140 (27%), Positives = 53/140 (37%), Gaps = 13/140 (9%)
Query: 452 ECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVD 511
ECP GY + C D +EC L +C + C NTRG Y C C PG P ++
Sbjct: 607 ECPQGYKRL-NLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRS----- 659
Query: 512 ECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDEC-VQEPRVCPHACENV 568
C +A + C+ + G CT P + C + + E CP
Sbjct: 660 RCVSDKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEA 719
Query: 569 VGSYICKCPEGYRRTSAPQD 588
CP G+ T A D
Sbjct: 720 FREI---CPAGHGYTYASSD 736
Score = 52.0 bits (119), Expect = 9e-06
Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 773 PAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECER---DT 829
PAG +EC + + C Y C C G++LD C DV+EC+
Sbjct: 1726 PAGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPA 1785
Query: 830 HTCQQ-ICSNTEGSYECSCEDGY 851
C C NTEGSY C C GY
Sbjct: 1786 VLCVHGYCENTEGSYRCHCSPGY 1808
Score = 51.6 bits (118), Expect = 1e-05
Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 7/65 (10%)
Query: 565 CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED---LCSGGVCINTDGSFLCD 621
C V Y C C EG++ +A AC D+NEC++ LC G C NT+GS+ C
Sbjct: 1748 CVRVREGYTCDCFEGFQLDAAHM----ACVDVNECDDLNGPAVLCVHGYCENTEGSYRCH 1803
Query: 622 CDAGF 626
C G+
Sbjct: 1804 CSPGY 1808
Score = 51.2 bits (117), Expect = 2e-05
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 9/113 (7%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDEC-SWGRPPCRGMAQCVNLPGAFECR 136
C P Q C GY+ N +H C+D++EC + G C+ A+CVN G++ C
Sbjct: 592 CPPRPASPVIENGQLECPQGYKRLNLTH-CQDINECLTLGL--CKD-AECVNTRGSYLCT 647
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVC 189
C PG L PS C V + + G C ++G C + + +C
Sbjct: 648 CRPGLMLDPSRSRC--VSDKAISML--QGLCYRSLGPGTCTLPLAQRITKQIC 696
Score = 50.8 bits (116), Expect = 2e-05
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 3/84 (3%)
Query: 60 PVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPP 119
P E +EC I+ C+ G C G+ C C G++ D C DV+EC P
Sbjct: 1726 PAGFEGLQAEECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGP 1784
Query: 120 CRGMAQ--CVNLPGAFECRCPPGY 141
C N G++ C C PGY
Sbjct: 1785 AVLCVHGYCENTEGSYRCHCSPGY 1808
Score = 50.0 bits (114), Expect = 4e-05
Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 2/78 (2%)
Query: 218 CDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE 277
C G+K C D+NEC G+ C++ C NT GS+ C C PG L C
Sbjct: 608 CPQGYKRLNLTHCQDINECLTLGL-CKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKA 666
Query: 278 CDELPHPCGRDGNP-SCT 294
L C R P +CT
Sbjct: 667 ISMLQGLCYRSLGPGTCT 684
Score = 48.8 bits (111), Expect = 8e-05
Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 4/83 (4%)
Query: 508 VDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDEC--VQEPRV-CPHA 564
+ +EC RC + C C G+ + A + C D++EC + P V C H
Sbjct: 1732 LQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHG 1791
Query: 565 -CENVVGSYICKCPEGYRRTSAP 586
CEN GSY C C GY + P
Sbjct: 1792 YCENTEGSYRCHCSPGYVAEAGP 1814
Score = 48.4 bits (110), Expect = 1e-04
Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 5/64 (7%)
Query: 290 NPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKEL--PYV-CAGGECRNFNGGYVCEC 344
N C GY C C G++L CVD +EC +L P V C G C N G Y C C
Sbjct: 1745 NGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHC 1804
Query: 345 PAGW 348
G+
Sbjct: 1805 SPGY 1808
Score = 47.6 bits (108), Expect = 2e-04
Identities = 44/152 (28%), Positives = 57/152 (37%), Gaps = 9/152 (5%)
Query: 4 NEEDQSCAGAVGVPQTKYLCCCSVGHAWGAP-CEACPPR-GSPAHTALCGEKPGEYINPV 61
N + CA + T+ CC SVG WG C CPPR SP E P Y
Sbjct: 557 NTVNGQCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQGYKRLN 616
Query: 62 TNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
+ I+EC + LCK C +T + C C G D + C S +
Sbjct: 617 LTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISM----LQ 671
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
G+ C G C P R+T + C V
Sbjct: 672 GL--CYRSLGPGTCTLPLAQRITKQICCCSRV 701
Score = 44.0 bits (99), Expect = 0.002
Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 13/115 (11%)
Query: 177 ECKPGYT-LRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVN 234
EC GY L C+D++EC +C++ C N G+YLC C G P+ CV
Sbjct: 607 ECPQGYKRLNLTHCQDINECLT-LGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVS-- 663
Query: 235 ECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV-----DECDELPHP 284
+ + G C ++G C +T C V EC++ P P
Sbjct: 664 ---DKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLP 715
Score = 42.7 bits (96), Expect = 0.005
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 10 CAGAVGVPQTKYL-CCCSVGHAWGAPCEACPPRGSPAHTALC 50
C+ + +T Y CCC G AW C CPPR S + LC
Sbjct: 1595 CSEPLRGHRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLC 1636
Score = 41.5 bits (93), Expect = 0.012
Identities = 21/54 (38%), Positives = 25/54 (46%), Gaps = 1/54 (1%)
Query: 767 CGPGYRPAGEV-CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
C GY+ C D++EC D C NT GSY C CR G LD + C
Sbjct: 608 CPQGYKRLNLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRC 661
Score = 39.9 bits (89), Expect = 0.038
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 14/84 (16%)
Query: 749 DECAAIPGLCAPGR-------FRCVCGPGYR--PAGEVCADVDECAVRPPPC----DQLC 795
+EC + G C GR + C C G++ A C DV+EC P C
Sbjct: 1735 EECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYC 1793
Query: 796 HNTDGSYDCLCRTGYELDEDGANC 819
NT+GSY C C GY + +C
Sbjct: 1794 ENTEGSYRCHCSPGYVAEAGPPHC 1817
Score = 39.1 bits (87), Expect = 0.066
Identities = 14/23 (60%), Positives = 17/23 (73%)
Query: 436 VCVGGRCVNTDGSFRCECPDGYV 458
+CV G C NT+GS+RC C GYV
Sbjct: 1787 LCVHGYCENTEGSYRCHCSPGYV 1809
Score = 34.7 bits (76), Expect = 1.4
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 8/69 (11%)
Query: 784 CAVRPP-PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI-CSNTEG 841
CA PP P + N G +C GY+ + +C+D++EC C+ C NT G
Sbjct: 589 CAPCPPRPASPVIEN--GQLEC--PQGYKR-LNLTHCQDINEC-LTLGLCKDAECVNTRG 642
Query: 842 SYECSCEDG 850
SY C+C G
Sbjct: 643 SYLCTCRPG 651
Score = 33.9 bits (74), Expect = 2.5
Identities = 12/32 (37%), Positives = 15/32 (46%)
Query: 328 CAGGECRNFNGGYVCECPAGWRFDKTAAVCVD 359
C G C GY C+C G++ D CVD
Sbjct: 1743 CENGRCVRVREGYTCDCFEGFQLDAAHMACVD 1774
>BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming growth
factor beta binding protein 2 protein.
Length = 1821
Score = 445 bits (1097), Expect = e-124
Identities = 277/800 (34%), Positives = 373/800 (46%), Gaps = 94/800 (11%)
Query: 61 VTNETKPIDECDI-MPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPP 119
VT T ID C +C PGTC + P G++C C GY+ + C D +EC R P
Sbjct: 838 VTLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECL--RDP 895
Query: 120 CRGMAQCVNLPGAFECRCPPGYRLTPS--LDECEDVDECGDQRICDHGDCRNTIGSYRCE 177
C+G +C+N G++ C C PGY L S EC+D++EC +C G C NT GSY CE
Sbjct: 896 CKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCE 955
Query: 178 CKPGYTL-RENVCRDVDECSRPRPVCRNGTCENLPGAYLC-HCDDGFKAGPNNDCVDVNE 235
C GY + R+ C+D++EC P C +G C N PG+Y C C++G++ G + CVDVNE
Sbjct: 956 CDQGYIMVRKGHCQDINECRHPG-TCPDGRCVNSPGSYTCLACEEGYR-GQSGSCVDVNE 1013
Query: 236 CREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC-DELPHPCGRDGNPSCT 294
C G VC +G+C N GSFRC C GY +T+D + C+DVDEC P G C
Sbjct: 1014 CLTPG-VCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGL-----CL 1067
Query: 295 NTNGGYECS-CGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVC-ECPAGWRF 350
NT G + CS C G+ + G C D DEC P VC G C N G + C +C G+R
Sbjct: 1068 NTEGSFACSACENGYWVNEDGTACEDLDECA-FPGVCPSGVCTNTAGSFSCKDCDGGYRP 1126
Query: 351 DKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
C D DE E P+ C G C+ +
Sbjct: 1127 SPLGDSCED------VDECED-------------PQSSCLGGE-----CKNTVG----SY 1158
Query: 411 MRICQGGMGRPNLT--QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
+C G N T +D++EC G C+N+ GSF C C G+V A G SC D
Sbjct: 1159 QCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQD 1218
Query: 469 ADECAL-DPRICGNGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAE-GRASC-TFRC 524
DECA DP C G C NT G + C C GF P+ CVD+DEC + G C T++C
Sbjct: 1219 VDECATTDP--CVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKC 1276
Query: 525 HNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYR 581
N+ GS+RC C G+ +A +G C DIDEC + H C+N GS+ C C +G+
Sbjct: 1277 ENSPGSYRCVLGCQPGFHMAPNG-DCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFE 1335
Query: 582 RTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP--SEDGTDCIDRR 639
+ + D C D+NECE +C +C N +GSFLC C + E +++G C R
Sbjct: 1336 ISPSGWD----CVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEG-HCRPRG 1390
Query: 640 TGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECEL 699
G S + T+A+CCCT GA+WG C+L
Sbjct: 1391 AGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDL 1450
Query: 700 CPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAI-PGLC 758
CP+ S ++C + ++ D DEC PGLC
Sbjct: 1451 CPSEDSAEFSEICPS-------------GKGYIPVEGAWTFGQTMYTDADECVIFGPGLC 1497
Query: 759 APGR-------FRCVCGPG--YRPAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRT 808
GR + C+C PG Y + + C D DEC + C+ C NT+GS+ C C
Sbjct: 1498 PNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSP 1555
Query: 809 GYELDEDGANCRDVDECERD 828
LD C + D
Sbjct: 1556 PLTLDLSQQRCMNSTSSTED 1575
Score = 281 bits (689), Expect = 7e-75
Identities = 176/538 (32%), Positives = 240/538 (44%), Gaps = 54/538 (10%)
Query: 50 CGEKPGEYI-NPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR 108
C + G Y +P+ + + +DEC+ C G C +T +QC C G++ N + +C
Sbjct: 1117 CKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGT-VCE 1175
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCR 168
DV+EC G C +C+N G+F C C PG+ C+DVDEC C G C
Sbjct: 1176 DVNEC-MGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCV 1234
Query: 169 NTIGSYRCECKPGY--TLRENVCRDVDEC-SRPRPVCRNGTCENLPGAYLC--HCDDGFK 223
NT GS+ C C+ G+ + C D+DEC PVC CEN PG+Y C C GF
Sbjct: 1235 NTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFH 1294
Query: 224 AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPH 283
PN DC+D++EC M +G C NT GSFRC C G+ ++ G +C DV+EC+ +
Sbjct: 1295 MAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLA 1354
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGEC--RNFNGGYV 341
CG C N G + C C + D +E Y G C R G +
Sbjct: 1355 VCGA---ALCENVEGSFLCLCAS----------DLEE-----YDAQEGHCRPRGAGGQSM 1396
Query: 342 CECPAGWRFDKTAAVCVDERKELCYDEWEA-GRCHRARPLQLARPECCCSEGAAWGRYCE 400
E P G D A R + CY + C + ECCC++GA+WG C+
Sbjct: 1397 SEAPTG---DHAPA---PTRMD-CYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACD 1449
Query: 401 RCPAPDSAEFMRICQGGMG----------RPNLTQDLDECRV-RPDVCVGGRCVNTDGSF 449
CP+ DSAEF IC G G + D DEC + P +C GRC+NT +
Sbjct: 1450 LCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGY 1509
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG-PDQTCV 508
C C G+ C D DEC C NG C NT G + C CSP T Q C+
Sbjct: 1510 VCLCNPGFHYDASHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSPPLTLDLSQQRCM 1567
Query: 509 DVDECAEGRASCTFR---CHNTAGSFRCTCPY-GYAVAADGVHCRDIDECVQEPRVCP 562
+ E C + C+ P G+ C+D + Q+ +CP
Sbjct: 1568 NSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCP 1625
Score = 275 bits (674), Expect = 5e-73
Identities = 213/653 (32%), Positives = 302/653 (46%), Gaps = 85/653 (13%)
Query: 19 TKYLCCCS-VGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQL 77
TK +CCCS VG AWG+ CE CP G+ A +C G Y ++ + + + +L
Sbjct: 692 TKQICCCSRVGKAWGSECEKCPLPGTEAFREICPAGHG-YTYASSDIRLSMRKAE-EEEL 749
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC--VNLPGAFEC 135
+P + G G + D G P +G +Q V
Sbjct: 750 ARPPREQGQRSS---GALPGPAERQPLRVVTDT-WLEAGTIPDKGDSQAGQVTTSVTHAP 805
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCE-CKPGYTLRENVCRDVDE 194
G TP + E + + E ++++ D T+ + + C G T NVC
Sbjct: 806 AWVTGNATTPPMPE-QGIAEIQEEQVTPSTDVLVTLSTPGIDRCAAGAT---NVCGPGTC 861
Query: 195 CSRP---RPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNT 251
+ P R VC G + AY C D +N+C+ + C+ G C N
Sbjct: 862 VNLPDGYRCVCSPGYQLHPSQAY---CTD------DNECLR-DPCKGKGR-CIN-----R 905
Query: 252 VGSFRCECAPGYTLTADG--RNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
VGS+ C C PGYTL G + C+D++EC++ P C CTNT G Y C C G+
Sbjct: 906 VGSYSCFCYPGYTLATSGATQECQDINECEQ-PGVC---SGGQCTNTEGSYHCECDQGYI 961
Query: 310 LVGR-RCVDRDECKELPYVCAGGECRNFNGGYVC-ECPAGWRFDKTAAVCVDERKELCYD 367
+V + C D +EC+ P C G C N G Y C C G+R + V V+E C
Sbjct: 962 MVRKGHCQDINECRH-PGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNE----CL- 1015
Query: 368 EWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDL 427
G C A +C EG+ RC E +G QD+
Sbjct: 1016 --TPGVC--------AHGKCTNLEGSF------RCSCEQGYEVTSDEKG-------CQDV 1052
Query: 428 DECRVRPDVCVGGRCVNTDGSFRCE-CPDGYVLAPDGLSCVDADECALDPRICGNGTCSN 486
DEC R C G C+NT+GSF C C +GY + DG +C D DECA P +C +G C+N
Sbjct: 1053 DECASRAS-CPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVCPSGVCTN 1110
Query: 487 TRGGYECQ-CSPGFTQGP-DQTCVDVDECAEGRASCT-FRCHNTAGSFRCTCPYGYAVAA 543
T G + C+ C G+ P +C DVDEC + ++SC C NT GS++C CP G+ + A
Sbjct: 1111 TAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQL-A 1169
Query: 544 DGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQ 602
+G C D++EC+ E PH C N GS+ C C G+ SA + +C+D++EC
Sbjct: 1170 NGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGF--VSA--EGGTSCQDVDEC-AT 1224
Query: 603 EDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSG--RCE 653
D C GG C+NT+GSF C C+ GF+PS + +C+D Y V G +CE
Sbjct: 1225 TDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCE 1277
Score = 273 bits (669), Expect = 2e-72
Identities = 206/676 (30%), Positives = 273/676 (40%), Gaps = 71/676 (10%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
++EC + P +C G C + F+C C+ GYE + C+DVDEC+ R C C+
Sbjct: 1011 VNEC-LTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECA-SRASCP-TGLCL 1067
Query: 128 NLPGAFECR-CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRC-ECKPGYTLR 185
N G+F C C GY + CED+DEC +C G C NT GS+ C +C GY
Sbjct: 1068 NTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPS 1127
Query: 186 E--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC 243
+ C DVDEC P+ C G C+N G+Y C C GF+ C DVNEC
Sbjct: 1128 PLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCA 1187
Query: 244 RNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS 303
+G C N+ GSF C CAPG+ G +C+DVDEC PC C NT G + C
Sbjct: 1188 PHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDEC-ATTDPC---VGGHCVNTEGSFNCL 1243
Query: 304 CGAGWK--LVGRRCVDRDECKEL-PYVCAGGECRNFNGGYVC--ECPAGWRFDKTAAVCV 358
C G++ CVD DEC++ VC +C N G Y C C G+ C+
Sbjct: 1244 CETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGD-CI 1302
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
D + C ++ G H C C +G C + E M G
Sbjct: 1303 D--IDECANDTMCG-SHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAA 1359
Query: 419 GRPNL--------TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDG-YVLAPDGLSCVDA 469
N+ DL+E + C R G E P G + AP + C
Sbjct: 1360 LCENVEGSFLCLCASDLEEYDAQEGHC---RPRGAGGQSMSEAPTGDHAPAPTRMDCYSG 1416
Query: 470 DECALDPRICGNGTCSNTRG----GYECQCSPGFTQGPDQTCVDVDEC-AEGRASCTFRC 524
+ G+ CS+ G EC C+ G + G C D C +E A + C
Sbjct: 1417 QK--------GHAPCSSVLGRNTTQAECCCTQGASWG--DAC---DLCPSEDSAEFSEIC 1463
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECV-QEPRVCPHA-CENVVGSYICKCPEGYRR 582
+ G P A D DECV P +CP+ C N V Y+C C G+
Sbjct: 1464 PSGKGYI----PVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHY 1519
Query: 583 TSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGT 642
+ S CED +EC Q+ C G C+NT+GSF C C +D
Sbjct: 1520 DA----SHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSPPL--------TLDLSQQR 1565
Query: 643 CYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGH-VTKAQCCCTLGAAWGSECELCP 701
C S S P+ GH T +CCC G AW +C LCP
Sbjct: 1566 CMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCP 1625
Query: 702 APGSPARLDLCTAVNL 717
S LC +
Sbjct: 1626 PRSSEVYAQLCNVARI 1641
Score = 225 bits (550), Expect = 5e-58
Identities = 154/463 (33%), Positives = 200/463 (43%), Gaps = 46/463 (9%)
Query: 424 TQDLDECRV-RPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRIC-GN 481
T +D C +VC G CVN +RC C GY L P C D +EC DP C G
Sbjct: 842 TPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDP--CKGK 899
Query: 482 GTCSNTRGGYECQCSPGFT---QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYG 538
G C N G Y C C PG+T G Q C D++EC + +C NT GS+ C C G
Sbjct: 900 GRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQG 959
Query: 539 YAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYIC-KCPEGYRRTSAPQDSENACEDI 596
Y + G HC+DI+EC + P CP C N GSY C C EGYR S +C D+
Sbjct: 960 YIMVRKG-HCQDINEC-RHPGTCPDGRCVNSPGSYTCLACEEGYRGQSG------SCVDV 1011
Query: 597 NECEEQEDLCSGGVCINTDGSFLCDCDAGFEPS------EDGTDCIDRR---TGTCYRSL 647
NEC +C+ G C N +GSF C C+ G+E + +D +C R TG C +
Sbjct: 1012 NECLTP-GVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTE 1070
Query: 648 VSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECE--LCPAP-- 703
S C G C T G+ +C+ P+P
Sbjct: 1071 GSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLG 1130
Query: 704 GSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLD--VFADVDEC-----AAIPG 756
S +D C + + V DV+EC A G
Sbjct: 1131 DSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHG 1190
Query: 757 LC--APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
C + G F C+C PG+ A G C DVDECA P C NT+GS++CLC TG++
Sbjct: 1191 ECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQP 1250
Query: 813 DEDGANCRDVDECE--RDTHTCQQICSNTEGSYEC--SCEDGY 851
+ C D+DECE D C N+ GSY C C+ G+
Sbjct: 1251 SPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGF 1293
Score = 183 bits (446), Expect = 2e-45
Identities = 133/418 (31%), Positives = 172/418 (41%), Gaps = 37/418 (8%)
Query: 464 LSCVDADECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCT 521
LS D CA +CG GTC N GY C CSPG+ P Q C D +EC
Sbjct: 840 LSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGK 899
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGV--HCRDIDECVQEPRVCPHA-CENVVGSYICKCPE 578
RC N GS+ C C GY +A G C+DI+EC ++P VC C N GSY C+C +
Sbjct: 900 GRCINRVGSYSCFCYPGYTLATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECDQ 958
Query: 579 GYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC-DCDAGFEPSE----DGT 633
GY + C+DINEC C G C+N+ GS+ C C+ G+ D
Sbjct: 959 GYIMVR-----KGHCQDINECRHP-GTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVN 1012
Query: 634 DCIDRRT---GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLG 690
+C+ G C S RC E T C T G
Sbjct: 1013 ECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPT-GLCLNTEG 1071
Query: 691 AAWGSECE---LCPAPGSPAR-LDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXL---D 743
+ S CE G+ LD C + P D
Sbjct: 1072 SFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGD 1131
Query: 744 VFADVDEC-----AAIPGLC--APGRFRCVCGPGYRPA-GEVCADVDECAVRPPPCDQ-L 794
DVDEC + + G C G ++C+C G++ A G VC DV+EC
Sbjct: 1132 SCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGE 1191
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
C N+ GS+ CLC G+ E G +C+DVDEC C NTEGS+ C CE G++
Sbjct: 1192 CLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQ 1249
Score = 96.7 bits (230), Expect = 3e-19
Identities = 53/125 (42%), Positives = 67/125 (53%), Gaps = 14/125 (11%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHN 797
DV+EC PG+CA G+ FRC C GY + C DVDECA R LC N
Sbjct: 1010 DVNECLT-PGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLN 1068
Query: 798 TDGSYDC-LCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC-SCEDGYEKR- 854
T+GS+ C C GY ++EDG C D+DEC +C+NT GS+ C C+ GY
Sbjct: 1069 TEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSP 1128
Query: 855 -GDAC 858
GD+C
Sbjct: 1129 LGDSC 1133
Score = 92.3 bits (219), Expect = 7e-18
Identities = 51/124 (41%), Positives = 66/124 (53%), Gaps = 14/124 (11%)
Query: 747 DVDECAAIPGLC-------APGRFRCV-CGPGYRPAGEVCADVDECAVRPPPCDQ-LCHN 797
D++EC PG C +PG + C+ C GYR C DV+EC + P C C N
Sbjct: 970 DINECRH-PGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNEC-LTPGVCAHGKCTN 1027
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGY--EKR 854
+GS+ C C GYE+ D C+DVDEC +C NTEGS+ CS CE+GY +
Sbjct: 1028 LEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNED 1087
Query: 855 GDAC 858
G AC
Sbjct: 1088 GTAC 1091
Score = 87.4 bits (207), Expect = 2e-16
Identities = 52/149 (34%), Positives = 69/149 (46%), Gaps = 13/149 (8%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVT-----NE 64
C+ +G T+ CCC+ G +WG C+ CP S + +C G YI PV +
Sbjct: 1423 CSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKG-YI-PVEGAWTFGQ 1480
Query: 65 T--KPIDECDIM-PQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
T DEC I P LC G C +T G+ C C+ G+ +D + C D DEC C
Sbjct: 1481 TMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQ--DLACE 1538
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDEC 150
+CVN G+F C C P L S C
Sbjct: 1539 N-GECVNTEGSFHCFCSPPLTLDLSQQRC 1566
Score = 87.0 bits (206), Expect = 3e-16
Identities = 47/119 (39%), Positives = 65/119 (54%), Gaps = 14/119 (11%)
Query: 747 DVDECAA----IPGLCA--PGRFRCVCGPGYRPAGE--VCADVDECA-VRPPPCDQ-LCH 796
DVDECA + G C G F C+C G++P+ E C D+DEC P C C
Sbjct: 1218 DVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCE 1277
Query: 797 NTDGSYDCL--CRTGYELDEDGANCRDVDECERDTHT-CQQICSNTEGSYECSCEDGYE 852
N+ GSY C+ C+ G+ + +G +C D+DEC DT C NT+GS+ C C+ G+E
Sbjct: 1278 NSPGSYRCVLGCQPGFHMAPNG-DCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFE 1335
Score = 85.8 bits (203), Expect = 6e-16
Identities = 65/193 (33%), Positives = 83/193 (43%), Gaps = 18/193 (9%)
Query: 246 GRCR-NTVGSFRCECA-PGYTLTADGRNCRDVDEC--DELPHPCG-RDGNPSCTNTNGGY 300
GRC NTV +CA P LT C V L PC R +P N G
Sbjct: 552 GRCYLNTVNG---QCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIEN--GQL 606
Query: 301 ECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
EC G +L C D +EC L +C EC N G Y+C C G D + + CV +
Sbjct: 607 ECPQGYK-RLNLTHCQDINECLTLG-LCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSD 664
Query: 361 R-----KELCYDEWEAGRCHRARPLQLARPECCCSE-GAAWGRYCERCPAPDSAEFMRIC 414
+ + LCY G C ++ + CCCS G AWG CE+CP P + F IC
Sbjct: 665 KAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREIC 724
Query: 415 QGGMGRPNLTQDL 427
G G + D+
Sbjct: 725 PAGHGYTYASSDI 737
Score = 85.8 bits (203), Expect = 6e-16
Identities = 44/102 (43%), Positives = 57/102 (55%), Gaps = 9/102 (8%)
Query: 759 APGRFRCV--CGPGYR--PAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYEL 812
+PG +RCV C PG+ P G+ C D+DECA C C NTDGS+ CLC G+E+
Sbjct: 1279 SPGSYRCVLGCQPGFHMAPNGD-CIDIDECA-NDTMCGSHGFCDNTDGSFRCLCDQGFEI 1336
Query: 813 DEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEK 853
G +C DV+ECE C +C N EGS+ C C E+
Sbjct: 1337 SPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEE 1378
Score = 85.4 bits (202), Expect = 8e-16
Identities = 53/159 (33%), Positives = 71/159 (44%), Gaps = 32/159 (20%)
Query: 562 PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCD 621
P V+ + +CP+GY+R + C+DINEC LC C+NT GS+LC
Sbjct: 594 PRPASPVIENGQLECPQGYKRLNLTH-----CQDINECLTL-GLCKDAECVNTRGSYLCT 647
Query: 622 CDAGFEPSEDGTDCIDRRT-----GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXX 676
C G + C+ + G CYRSL G C
Sbjct: 648 CRPGLMLDPSRSRCVSDKAISMLQGLCYRSLGPGTC--------------------TLPL 687
Query: 677 XGHVTKAQCCCT-LGAAWGSECELCPAPGSPARLDLCTA 714
+TK CCC+ +G AWGSECE CP PG+ A ++C A
Sbjct: 688 AQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREICPA 726
Score = 84.2 bits (199), Expect = 2e-15
Identities = 54/125 (43%), Positives = 63/125 (50%), Gaps = 14/125 (11%)
Query: 747 DVDECAA---IP-GLC--APGRFRC-VCGPGY--RPAGEVCADVDECAVRPPPCDQ-LCH 796
DVDECA+ P GLC G F C C GY G C D+DECA P C +C
Sbjct: 1051 DVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVCPSGVCT 1109
Query: 797 NTDGSYDCL-CRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYE-K 853
NT GS+ C C GY G +C DVDECE +C C NT GSY+C C G++
Sbjct: 1110 NTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLA 1169
Query: 854 RGDAC 858
G C
Sbjct: 1170 NGTVC 1174
Score = 78.6 bits (185), Expect = 9e-14
Identities = 43/106 (40%), Positives = 59/106 (55%), Gaps = 10/106 (9%)
Query: 761 GRFRCVCGPGYR----PAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 815
G + C C PGY A + C D++EC +P C C NT+GSY C C GY +
Sbjct: 907 GSYSCFCYPGYTLATSGATQECQDINECE-QPGVCSGGQCTNTEGSYHCECDQGYIMVRK 965
Query: 816 GANCRDVDECERDTHTCQQ-ICSNTEGSYEC-SCEDGYEKRGDACV 859
G +C+D++EC R TC C N+ GSY C +CE+GY + +CV
Sbjct: 966 G-HCQDINEC-RHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCV 1009
Score = 70.1 bits (164), Expect = 3e-11
Identities = 31/75 (41%), Positives = 42/75 (56%), Gaps = 4/75 (5%)
Query: 202 CRNGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECRE---GGMVCRNGRCRNTVGSFRC 257
C NG C + Y C C +GF+ + CVDVNEC + ++C +G C NT GS+RC
Sbjct: 1743 CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC 1802
Query: 258 ECAPGYTLTADGRNC 272
C+PGY A +C
Sbjct: 1803 HCSPGYVAEAGPPHC 1817
Score = 67.7 bits (158), Expect = 2e-10
Identities = 37/93 (39%), Positives = 43/93 (46%), Gaps = 6/93 (6%)
Query: 461 PDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAE--GR 517
P G + A+EC + C NG C R GY C C GF CVDV+EC + G
Sbjct: 1726 PAGFEGLQAEECGI-LNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGP 1784
Query: 518 ASCTFR--CHNTAGSFRCTCPYGYAVAADGVHC 548
A C NT GS+RC C GY A HC
Sbjct: 1785 AVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHC 1817
Score = 65.3 bits (152), Expect = 9e-10
Identities = 48/134 (35%), Positives = 63/134 (47%), Gaps = 16/134 (11%)
Query: 365 CYDEWEAGRCHRARPL-QLARPECCC-SEGAAWG-RYCERCPAPDSAEFMRI----CQGG 417
CY G+C A PL +L E CC S GA WG C CP ++ + C G
Sbjct: 554 CYLNTVNGQC--ANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQG 611
Query: 418 MGRPNLT--QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
R NLT QD++EC + +C CVNT GS+ C C G +L P CV ++
Sbjct: 612 YKRLNLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISML 670
Query: 476 PRIC----GNGTCS 485
+C G GTC+
Sbjct: 671 QGLCYRSLGPGTCT 684
Score = 65.3 bits (152), Expect = 9e-10
Identities = 29/75 (38%), Positives = 42/75 (56%), Gaps = 4/75 (5%)
Query: 428 DECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC--ALDPRI-CGNGTC 484
+EC + + C GRCV + C+C +G+ L ++CVD +EC P + C +G C
Sbjct: 1735 EECGIL-NGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYC 1793
Query: 485 SNTRGGYECQCSPGF 499
NT G Y C CSPG+
Sbjct: 1794 ENTEGSYRCHCSPGY 1808
Score = 63.7 bits (148), Expect = 3e-09
Identities = 31/80 (38%), Positives = 43/80 (53%), Gaps = 7/80 (8%)
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTL--RENVCRDVDEC---SRPRPVCRNGTCE 208
+ECG C++G C Y C+C G+ L C DV+EC + P +C +G CE
Sbjct: 1735 EECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCE 1794
Query: 209 NLPGAYLCHCDDGF--KAGP 226
N G+Y CHC G+ +AGP
Sbjct: 1795 NTEGSYRCHCSPGYVAEAGP 1814
Score = 62.1 bits (144), Expect = 8e-09
Identities = 27/62 (43%), Positives = 35/62 (56%), Gaps = 4/62 (6%)
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQR----ICDHGDCRNTIGSYRCECKP 180
+CV + + C C G++L + C DV+EC D +C HG C NT GSYRC C P
Sbjct: 1747 RCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSP 1806
Query: 181 GY 182
GY
Sbjct: 1807 GY 1808
Score = 61.3 bits (142), Expect = 1e-08
Identities = 26/66 (39%), Positives = 33/66 (50%)
Query: 243 CRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC 302
C NGRC + C+C G+ L A C DV+ECD+L P + C NT G Y C
Sbjct: 1743 CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC 1802
Query: 303 SCGAGW 308
C G+
Sbjct: 1803 HCSPGY 1808
Score = 56.8 bits (131), Expect = 3e-07
Identities = 35/92 (38%), Positives = 40/92 (43%), Gaps = 10/92 (10%)
Query: 765 CVCGPGYRPA------GEVC-ADVDECAVRPPP-CDQ-LCHNTDGSYDCLCRTGYELDED 815
C G GY P G+ D DEC + P C C NT Y CLC G+ D
Sbjct: 1463 CPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDAS 1522
Query: 816 GANCRDVDECERDTHTCQQICSNTEGSYECSC 847
C D DEC+ D C NTEGS+ C C
Sbjct: 1523 HKKCEDHDECQ-DLACENGECVNTEGSFHCFC 1553
Score = 53.6 bits (123), Expect = 3e-06
Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Query: 134 ECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVD 193
+ CP GY+ +L C+D++EC +C +C NT GSY C C+PG L + R V
Sbjct: 605 QLECPQGYKRL-NLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVS 663
Query: 194 E 194
+
Sbjct: 664 D 664
Score = 52.4 bits (120), Expect = 7e-06
Identities = 39/140 (27%), Positives = 53/140 (37%), Gaps = 13/140 (9%)
Query: 452 ECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVD 511
ECP GY + C D +EC L +C + C NTRG Y C C PG P ++
Sbjct: 607 ECPQGYKRL-NLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRS----- 659
Query: 512 ECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDEC-VQEPRVCPHACENV 568
C +A + C+ + G CT P + C + + E CP
Sbjct: 660 RCVSDKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEA 719
Query: 569 VGSYICKCPEGYRRTSAPQD 588
CP G+ T A D
Sbjct: 720 FREI---CPAGHGYTYASSD 736
Score = 52.0 bits (119), Expect = 9e-06
Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 773 PAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECER---DT 829
PAG +EC + + C Y C C G++LD C DV+EC+
Sbjct: 1726 PAGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPA 1785
Query: 830 HTCQQ-ICSNTEGSYECSCEDGY 851
C C NTEGSY C C GY
Sbjct: 1786 VLCVHGYCENTEGSYRCHCSPGY 1808
Score = 51.6 bits (118), Expect = 1e-05
Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 7/65 (10%)
Query: 565 CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED---LCSGGVCINTDGSFLCD 621
C V Y C C EG++ +A AC D+NEC++ LC G C NT+GS+ C
Sbjct: 1748 CVRVREGYTCDCFEGFQLDAAHM----ACVDVNECDDLNGPAVLCVHGYCENTEGSYRCH 1803
Query: 622 CDAGF 626
C G+
Sbjct: 1804 CSPGY 1808
Score = 51.2 bits (117), Expect = 2e-05
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 9/113 (7%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDEC-SWGRPPCRGMAQCVNLPGAFECR 136
C P Q C GY+ N +H C+D++EC + G C+ A+CVN G++ C
Sbjct: 592 CPPRPASPVIENGQLECPQGYKRLNLTH-CQDINECLTLGL--CKD-AECVNTRGSYLCT 647
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVC 189
C PG L PS C V + + G C ++G C + + +C
Sbjct: 648 CRPGLMLDPSRSRC--VSDKAISML--QGLCYRSLGPGTCTLPLAQRITKQIC 696
Score = 50.8 bits (116), Expect = 2e-05
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 3/84 (3%)
Query: 60 PVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPP 119
P E +EC I+ C+ G C G+ C C G++ D C DV+EC P
Sbjct: 1726 PAGFEGLQAEECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGP 1784
Query: 120 CRGMAQ--CVNLPGAFECRCPPGY 141
C N G++ C C PGY
Sbjct: 1785 AVLCVHGYCENTEGSYRCHCSPGY 1808
Score = 50.0 bits (114), Expect = 4e-05
Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 2/78 (2%)
Query: 218 CDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE 277
C G+K C D+NEC G+ C++ C NT GS+ C C PG L C
Sbjct: 608 CPQGYKRLNLTHCQDINECLTLGL-CKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKA 666
Query: 278 CDELPHPCGRDGNP-SCT 294
L C R P +CT
Sbjct: 667 ISMLQGLCYRSLGPGTCT 684
Score = 48.8 bits (111), Expect = 8e-05
Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 4/83 (4%)
Query: 508 VDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDEC--VQEPRV-CPHA 564
+ +EC RC + C C G+ + A + C D++EC + P V C H
Sbjct: 1732 LQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHG 1791
Query: 565 -CENVVGSYICKCPEGYRRTSAP 586
CEN GSY C C GY + P
Sbjct: 1792 YCENTEGSYRCHCSPGYVAEAGP 1814
Score = 48.4 bits (110), Expect = 1e-04
Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 5/64 (7%)
Query: 290 NPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKEL--PYV-CAGGECRNFNGGYVCEC 344
N C GY C C G++L CVD +EC +L P V C G C N G Y C C
Sbjct: 1745 NGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHC 1804
Query: 345 PAGW 348
G+
Sbjct: 1805 SPGY 1808
Score = 47.6 bits (108), Expect = 2e-04
Identities = 44/152 (28%), Positives = 57/152 (37%), Gaps = 9/152 (5%)
Query: 4 NEEDQSCAGAVGVPQTKYLCCCSVGHAWGAP-CEACPPR-GSPAHTALCGEKPGEYINPV 61
N + CA + T+ CC SVG WG C CPPR SP E P Y
Sbjct: 557 NTVNGQCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQGYKRLN 616
Query: 62 TNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
+ I+EC + LCK C +T + C C G D + C S +
Sbjct: 617 LTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISM----LQ 671
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
G+ C G C P R+T + C V
Sbjct: 672 GL--CYRSLGPGTCTLPLAQRITKQICCCSRV 701
Score = 44.0 bits (99), Expect = 0.002
Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 13/115 (11%)
Query: 177 ECKPGYT-LRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVN 234
EC GY L C+D++EC +C++ C N G+YLC C G P+ CV
Sbjct: 607 ECPQGYKRLNLTHCQDINECLT-LGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVS-- 663
Query: 235 ECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV-----DECDELPHP 284
+ + G C ++G C +T C V EC++ P P
Sbjct: 664 ---DKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLP 715
Score = 42.7 bits (96), Expect = 0.005
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 10 CAGAVGVPQTKYL-CCCSVGHAWGAPCEACPPRGSPAHTALC 50
C+ + +T Y CCC G AW C CPPR S + LC
Sbjct: 1595 CSEPLRGHRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLC 1636
Score = 41.5 bits (93), Expect = 0.012
Identities = 21/54 (38%), Positives = 25/54 (46%), Gaps = 1/54 (1%)
Query: 767 CGPGYRPAGEV-CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
C GY+ C D++EC D C NT GSY C CR G LD + C
Sbjct: 608 CPQGYKRLNLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRC 661
Score = 39.9 bits (89), Expect = 0.038
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 14/84 (16%)
Query: 749 DECAAIPGLCAPGR-------FRCVCGPGYR--PAGEVCADVDECAVRPPPC----DQLC 795
+EC + G C GR + C C G++ A C DV+EC P C
Sbjct: 1735 EECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYC 1793
Query: 796 HNTDGSYDCLCRTGYELDEDGANC 819
NT+GSY C C GY + +C
Sbjct: 1794 ENTEGSYRCHCSPGYVAEAGPPHC 1817
Score = 39.1 bits (87), Expect = 0.066
Identities = 14/23 (60%), Positives = 17/23 (73%)
Query: 436 VCVGGRCVNTDGSFRCECPDGYV 458
+CV G C NT+GS+RC C GYV
Sbjct: 1787 LCVHGYCENTEGSYRCHCSPGYV 1809
Score = 34.7 bits (76), Expect = 1.4
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 8/69 (11%)
Query: 784 CAVRPP-PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI-CSNTEG 841
CA PP P + N G +C GY+ + +C+D++EC C+ C NT G
Sbjct: 589 CAPCPPRPASPVIEN--GQLEC--PQGYKR-LNLTHCQDINEC-LTLGLCKDAECVNTRG 642
Query: 842 SYECSCEDG 850
SY C+C G
Sbjct: 643 SYLCTCRPG 651
Score = 33.9 bits (74), Expect = 2.5
Identities = 12/32 (37%), Positives = 15/32 (46%)
Query: 328 CAGGECRNFNGGYVCECPAGWRFDKTAAVCVD 359
C G C GY C+C G++ D CVD
Sbjct: 1743 CENGRCVRVREGYTCDCFEGFQLDAAHMACVD 1774
>AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming growth
factor beta binding protein 2 variant protein.
Length = 1700
Score = 445 bits (1097), Expect = e-124
Identities = 277/800 (34%), Positives = 373/800 (46%), Gaps = 94/800 (11%)
Query: 61 VTNETKPIDECDI-MPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPP 119
VT T ID C +C PGTC + P G++C C GY+ + C D +EC R P
Sbjct: 717 VTLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECL--RDP 774
Query: 120 CRGMAQCVNLPGAFECRCPPGYRLTPS--LDECEDVDECGDQRICDHGDCRNTIGSYRCE 177
C+G +C+N G++ C C PGY L S EC+D++EC +C G C NT GSY CE
Sbjct: 775 CKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCE 834
Query: 178 CKPGYTL-RENVCRDVDECSRPRPVCRNGTCENLPGAYLC-HCDDGFKAGPNNDCVDVNE 235
C GY + R+ C+D++EC P C +G C N PG+Y C C++G++ G + CVDVNE
Sbjct: 835 CDQGYIMVRKGHCQDINECRHPG-TCPDGRCVNSPGSYTCLACEEGYR-GQSGSCVDVNE 892
Query: 236 CREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC-DELPHPCGRDGNPSCT 294
C G VC +G+C N GSFRC C GY +T+D + C+DVDEC P G C
Sbjct: 893 CLTPG-VCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGL-----CL 946
Query: 295 NTNGGYECS-CGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVC-ECPAGWRF 350
NT G + CS C G+ + G C D DEC P VC G C N G + C +C G+R
Sbjct: 947 NTEGSFACSACENGYWVNEDGTACEDLDECA-FPGVCPSGVCTNTAGSFSCKDCDGGYRP 1005
Query: 351 DKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
C D DE E P+ C G C+ +
Sbjct: 1006 SPLGDSCED------VDECED-------------PQSSCLGGE-----CKNTVG----SY 1037
Query: 411 MRICQGGMGRPNLT--QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
+C G N T +D++EC G C+N+ GSF C C G+V A G SC D
Sbjct: 1038 QCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQD 1097
Query: 469 ADECAL-DPRICGNGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAE-GRASC-TFRC 524
DECA DP C G C NT G + C C GF P+ CVD+DEC + G C T++C
Sbjct: 1098 VDECATTDP--CVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKC 1155
Query: 525 HNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYR 581
N+ GS+RC C G+ +A +G C DIDEC + H C+N GS+ C C +G+
Sbjct: 1156 ENSPGSYRCVLGCQPGFHMAPNG-DCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFE 1214
Query: 582 RTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP--SEDGTDCIDRR 639
+ + D C D+NECE +C +C N +GSFLC C + E +++G C R
Sbjct: 1215 ISPSGWD----CVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEG-HCRPRG 1269
Query: 640 TGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECEL 699
G S + T+A+CCCT GA+WG C+L
Sbjct: 1270 AGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDL 1329
Query: 700 CPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAI-PGLC 758
CP+ S ++C + ++ D DEC PGLC
Sbjct: 1330 CPSEDSAEFSEICPS-------------GKGYIPVEGAWTFGQTMYTDADECVIFGPGLC 1376
Query: 759 APGR-------FRCVCGPG--YRPAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRT 808
GR + C+C PG Y + + C D DEC + C+ C NT+GS+ C C
Sbjct: 1377 PNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSP 1434
Query: 809 GYELDEDGANCRDVDECERD 828
LD C + D
Sbjct: 1435 PLTLDLSQQRCMNSTSSTED 1454
Score = 283 bits (693), Expect = 2e-75
Identities = 177/538 (32%), Positives = 241/538 (44%), Gaps = 54/538 (10%)
Query: 50 CGEKPGEYI-NPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR 108
C + G Y +P+ + + +DEC+ C G C +T +QC C G++ N + +C
Sbjct: 996 CKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGT-VCE 1054
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCR 168
DV+EC G C +C+N G+F C C PG+ C+DVDEC C G C
Sbjct: 1055 DVNEC-MGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCV 1113
Query: 169 NTIGSYRCECKPGY--TLRENVCRDVDEC-SRPRPVCRNGTCENLPGAYLC--HCDDGFK 223
NT GS+ C C+ G+ + C D+DEC PVC CEN PG+Y C C GF
Sbjct: 1114 NTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFH 1173
Query: 224 AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPH 283
PN DC+D++EC M +G C NT GSFRC C G+ ++ G +C DV+EC+ +
Sbjct: 1174 MAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLA 1233
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGEC--RNFNGGYV 341
CG C N G + C C + D +E Y G C R G +
Sbjct: 1234 VCGA---ALCENVEGSFLCLCAS----------DLEE-----YDAQEGHCRPRGAGGQSM 1275
Query: 342 CECPAGWRFDKTAAVCVDERKELCYDEWEA-GRCHRARPLQLARPECCCSEGAAWGRYCE 400
E P G D A R + CY + C + ECCC++GA+WG C+
Sbjct: 1276 SEAPTG---DHAPA---PTRMD-CYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACD 1328
Query: 401 RCPAPDSAEFMRICQGGMG----------RPNLTQDLDECRV-RPDVCVGGRCVNTDGSF 449
CP+ DSAEF IC G G + D DEC + P +C GRC+NT +
Sbjct: 1329 LCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGY 1388
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG-PDQTCV 508
C C G+ C D DEC C NG C NT G + C CSP T Q C+
Sbjct: 1389 VCLCNPGFHYDASHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSPPLTLDLSQQRCM 1446
Query: 509 DVDECAEGRASCTFR---CHNTAGSFRCTCPY-GYAVAADGVHCRDIDECVQEPRVCP 562
+ E C A + C+ P G+ C+D + Q+ +CP
Sbjct: 1447 NSTSSTEDLPDHDIHMDICWKKATNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCP 1504
Score = 275 bits (674), Expect = 5e-73
Identities = 213/653 (32%), Positives = 302/653 (46%), Gaps = 85/653 (13%)
Query: 19 TKYLCCCS-VGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQL 77
TK +CCCS VG AWG+ CE CP G+ A +C G Y ++ + + + +L
Sbjct: 571 TKQICCCSRVGKAWGSECEKCPLPGTEAFREICPAGHG-YTYASSDIRLSMRKAE-EEEL 628
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC--VNLPGAFEC 135
+P + G G + D G P +G +Q V
Sbjct: 629 ARPPREQGQRSS---GALPGPAERQPLRVVTDT-WLEAGTIPDKGDSQAGQVTTSVTHAP 684
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCE-CKPGYTLRENVCRDVDE 194
G TP + E + + E ++++ D T+ + + C G T NVC
Sbjct: 685 AWVTGNATTPPMPE-QGIAEIQEEQVTPSTDVLVTLSTPGIDRCAAGAT---NVCGPGTC 740
Query: 195 CSRP---RPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNT 251
+ P R VC G + AY C D +N+C+ + C+ G C N
Sbjct: 741 VNLPDGYRCVCSPGYQLHPSQAY---CTD------DNECLR-DPCKGKGR-CIN-----R 784
Query: 252 VGSFRCECAPGYTLTADG--RNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
VGS+ C C PGYTL G + C+D++EC++ P C CTNT G Y C C G+
Sbjct: 785 VGSYSCFCYPGYTLATSGATQECQDINECEQ-PGVC---SGGQCTNTEGSYHCECDQGYI 840
Query: 310 LVGR-RCVDRDECKELPYVCAGGECRNFNGGYVC-ECPAGWRFDKTAAVCVDERKELCYD 367
+V + C D +EC+ P C G C N G Y C C G+R + V V+E C
Sbjct: 841 MVRKGHCQDINECRH-PGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNE----CL- 894
Query: 368 EWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDL 427
G C A +C EG+ RC E +G QD+
Sbjct: 895 --TPGVC--------AHGKCTNLEGSF------RCSCEQGYEVTSDEKG-------CQDV 931
Query: 428 DECRVRPDVCVGGRCVNTDGSFRCE-CPDGYVLAPDGLSCVDADECALDPRICGNGTCSN 486
DEC R C G C+NT+GSF C C +GY + DG +C D DECA P +C +G C+N
Sbjct: 932 DECASRAS-CPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVCPSGVCTN 989
Query: 487 TRGGYECQ-CSPGFTQGP-DQTCVDVDECAEGRASCT-FRCHNTAGSFRCTCPYGYAVAA 543
T G + C+ C G+ P +C DVDEC + ++SC C NT GS++C CP G+ + A
Sbjct: 990 TAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQL-A 1048
Query: 544 DGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQ 602
+G C D++EC+ E PH C N GS+ C C G+ SA + +C+D++EC
Sbjct: 1049 NGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGF--VSA--EGGTSCQDVDEC-AT 1103
Query: 603 EDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSG--RCE 653
D C GG C+NT+GSF C C+ GF+PS + +C+D Y V G +CE
Sbjct: 1104 TDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCE 1156
Score = 273 bits (670), Expect = 2e-72
Identities = 206/676 (30%), Positives = 273/676 (40%), Gaps = 71/676 (10%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
++EC + P +C G C + F+C C+ GYE + C+DVDEC+ R C C+
Sbjct: 890 VNEC-LTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECA-SRASCP-TGLCL 946
Query: 128 NLPGAFECR-CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRC-ECKPGYTLR 185
N G+F C C GY + CED+DEC +C G C NT GS+ C +C GY
Sbjct: 947 NTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPS 1006
Query: 186 E--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC 243
+ C DVDEC P+ C G C+N G+Y C C GF+ C DVNEC
Sbjct: 1007 PLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCA 1066
Query: 244 RNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS 303
+G C N+ GSF C CAPG+ G +C+DVDEC PC C NT G + C
Sbjct: 1067 PHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDEC-ATTDPC---VGGHCVNTEGSFNCL 1122
Query: 304 CGAGWK--LVGRRCVDRDECKEL-PYVCAGGECRNFNGGYVC--ECPAGWRFDKTAAVCV 358
C G++ CVD DEC++ VC +C N G Y C C G+ C+
Sbjct: 1123 CETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGD-CI 1181
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
D + C ++ G H C C +G C + E M G
Sbjct: 1182 D--IDECANDTMCG-SHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAA 1238
Query: 419 GRPNL--------TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDG-YVLAPDGLSCVDA 469
N+ DL+E + C R G E P G + AP + C
Sbjct: 1239 LCENVEGSFLCLCASDLEEYDAQEGHC---RPRGAGGQSMSEAPTGDHAPAPTRMDCYSG 1295
Query: 470 DECALDPRICGNGTCSNTRG----GYECQCSPGFTQGPDQTCVDVDEC-AEGRASCTFRC 524
+ G+ CS+ G EC C+ G + G C D C +E A + C
Sbjct: 1296 QK--------GHAPCSSVLGRNTTQAECCCTQGASWG--DAC---DLCPSEDSAEFSEIC 1342
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECV-QEPRVCPHA-CENVVGSYICKCPEGYRR 582
+ G P A D DECV P +CP+ C N V Y+C C G+
Sbjct: 1343 PSGKGYI----PVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHY 1398
Query: 583 TSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGT 642
+ S CED +EC Q+ C G C+NT+GSF C C +D
Sbjct: 1399 DA----SHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSPPL--------TLDLSQQR 1444
Query: 643 CYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGH-VTKAQCCCTLGAAWGSECELCP 701
C S S P+ GH T +CCC G AW +C LCP
Sbjct: 1445 CMNSTSSTEDLPDHDIHMDICWKKATNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCP 1504
Query: 702 APGSPARLDLCTAVNL 717
S LC +
Sbjct: 1505 PRSSEVYAQLCNVARI 1520
Score = 225 bits (550), Expect = 5e-58
Identities = 154/463 (33%), Positives = 200/463 (43%), Gaps = 46/463 (9%)
Query: 424 TQDLDECRV-RPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRIC-GN 481
T +D C +VC G CVN +RC C GY L P C D +EC DP C G
Sbjct: 721 TPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDP--CKGK 778
Query: 482 GTCSNTRGGYECQCSPGFT---QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYG 538
G C N G Y C C PG+T G Q C D++EC + +C NT GS+ C C G
Sbjct: 779 GRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQG 838
Query: 539 YAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYIC-KCPEGYRRTSAPQDSENACEDI 596
Y + G HC+DI+EC + P CP C N GSY C C EGYR S +C D+
Sbjct: 839 YIMVRKG-HCQDINEC-RHPGTCPDGRCVNSPGSYTCLACEEGYRGQSG------SCVDV 890
Query: 597 NECEEQEDLCSGGVCINTDGSFLCDCDAGFEPS------EDGTDCIDRR---TGTCYRSL 647
NEC +C+ G C N +GSF C C+ G+E + +D +C R TG C +
Sbjct: 891 NECLTP-GVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTE 949
Query: 648 VSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECE--LCPAP-- 703
S C G C T G+ +C+ P+P
Sbjct: 950 GSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLG 1009
Query: 704 GSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLD--VFADVDEC-----AAIPG 756
S +D C + + V DV+EC A G
Sbjct: 1010 DSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHG 1069
Query: 757 LC--APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
C + G F C+C PG+ A G C DVDECA P C NT+GS++CLC TG++
Sbjct: 1070 ECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQP 1129
Query: 813 DEDGANCRDVDECE--RDTHTCQQICSNTEGSYEC--SCEDGY 851
+ C D+DECE D C N+ GSY C C+ G+
Sbjct: 1130 SPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGF 1172
Score = 183 bits (446), Expect = 2e-45
Identities = 133/418 (31%), Positives = 172/418 (41%), Gaps = 37/418 (8%)
Query: 464 LSCVDADECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCT 521
LS D CA +CG GTC N GY C CSPG+ P Q C D +EC
Sbjct: 719 LSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGK 778
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGV--HCRDIDECVQEPRVCPHA-CENVVGSYICKCPE 578
RC N GS+ C C GY +A G C+DI+EC ++P VC C N GSY C+C +
Sbjct: 779 GRCINRVGSYSCFCYPGYTLATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECDQ 837
Query: 579 GYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC-DCDAGFEPSE----DGT 633
GY + C+DINEC C G C+N+ GS+ C C+ G+ D
Sbjct: 838 GYIMVR-----KGHCQDINECRHP-GTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVN 891
Query: 634 DCIDRRT---GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLG 690
+C+ G C S RC E T C T G
Sbjct: 892 ECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPT-GLCLNTEG 950
Query: 691 AAWGSECE---LCPAPGSPAR-LDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXL---D 743
+ S CE G+ LD C + P D
Sbjct: 951 SFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGD 1010
Query: 744 VFADVDEC-----AAIPGLC--APGRFRCVCGPGYRPA-GEVCADVDECAVRPPPCDQ-L 794
DVDEC + + G C G ++C+C G++ A G VC DV+EC
Sbjct: 1011 SCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGE 1070
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
C N+ GS+ CLC G+ E G +C+DVDEC C NTEGS+ C CE G++
Sbjct: 1071 CLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQ 1128
Score = 96.7 bits (230), Expect = 3e-19
Identities = 53/125 (42%), Positives = 67/125 (53%), Gaps = 14/125 (11%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHN 797
DV+EC PG+CA G+ FRC C GY + C DVDECA R LC N
Sbjct: 889 DVNECLT-PGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLN 947
Query: 798 TDGSYDC-LCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC-SCEDGYEKR- 854
T+GS+ C C GY ++EDG C D+DEC +C+NT GS+ C C+ GY
Sbjct: 948 TEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSP 1007
Query: 855 -GDAC 858
GD+C
Sbjct: 1008 LGDSC 1012
Score = 92.3 bits (219), Expect = 7e-18
Identities = 51/124 (41%), Positives = 66/124 (53%), Gaps = 14/124 (11%)
Query: 747 DVDECAAIPGLC-------APGRFRCV-CGPGYRPAGEVCADVDECAVRPPPCDQ-LCHN 797
D++EC PG C +PG + C+ C GYR C DV+EC + P C C N
Sbjct: 849 DINECRH-PGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNEC-LTPGVCAHGKCTN 906
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGY--EKR 854
+GS+ C C GYE+ D C+DVDEC +C NTEGS+ CS CE+GY +
Sbjct: 907 LEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNED 966
Query: 855 GDAC 858
G AC
Sbjct: 967 GTAC 970
Score = 87.4 bits (207), Expect = 2e-16
Identities = 52/149 (34%), Positives = 69/149 (46%), Gaps = 13/149 (8%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVT-----NE 64
C+ +G T+ CCC+ G +WG C+ CP S + +C G YI PV +
Sbjct: 1302 CSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKG-YI-PVEGAWTFGQ 1359
Query: 65 T--KPIDECDIM-PQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
T DEC I P LC G C +T G+ C C+ G+ +D + C D DEC C
Sbjct: 1360 TMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQ--DLACE 1417
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDEC 150
+CVN G+F C C P L S C
Sbjct: 1418 N-GECVNTEGSFHCFCSPPLTLDLSQQRC 1445
Score = 87.0 bits (206), Expect = 3e-16
Identities = 47/119 (39%), Positives = 65/119 (54%), Gaps = 14/119 (11%)
Query: 747 DVDECAA----IPGLCA--PGRFRCVCGPGYRPAGE--VCADVDECA-VRPPPCDQ-LCH 796
DVDECA + G C G F C+C G++P+ E C D+DEC P C C
Sbjct: 1097 DVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCE 1156
Query: 797 NTDGSYDCL--CRTGYELDEDGANCRDVDECERDTHT-CQQICSNTEGSYECSCEDGYE 852
N+ GSY C+ C+ G+ + +G +C D+DEC DT C NT+GS+ C C+ G+E
Sbjct: 1157 NSPGSYRCVLGCQPGFHMAPNG-DCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFE 1214
Score = 85.8 bits (203), Expect = 6e-16
Identities = 65/193 (33%), Positives = 83/193 (43%), Gaps = 18/193 (9%)
Query: 246 GRCR-NTVGSFRCECA-PGYTLTADGRNCRDVDEC--DELPHPCG-RDGNPSCTNTNGGY 300
GRC NTV +CA P LT C V L PC R +P N G
Sbjct: 431 GRCYLNTVNG---QCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIEN--GQL 485
Query: 301 ECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
EC G +L C D +EC L +C EC N G Y+C C G D + + CV +
Sbjct: 486 ECPQGYK-RLNLTHCQDINECLTLG-LCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSD 543
Query: 361 R-----KELCYDEWEAGRCHRARPLQLARPECCCSE-GAAWGRYCERCPAPDSAEFMRIC 414
+ + LCY G C ++ + CCCS G AWG CE+CP P + F IC
Sbjct: 544 KAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREIC 603
Query: 415 QGGMGRPNLTQDL 427
G G + D+
Sbjct: 604 PAGHGYTYASSDI 616
Score = 85.8 bits (203), Expect = 6e-16
Identities = 44/102 (43%), Positives = 57/102 (55%), Gaps = 9/102 (8%)
Query: 759 APGRFRCV--CGPGYR--PAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYEL 812
+PG +RCV C PG+ P G+ C D+DECA C C NTDGS+ CLC G+E+
Sbjct: 1158 SPGSYRCVLGCQPGFHMAPNGD-CIDIDECA-NDTMCGSHGFCDNTDGSFRCLCDQGFEI 1215
Query: 813 DEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEK 853
G +C DV+ECE C +C N EGS+ C C E+
Sbjct: 1216 SPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEE 1257
Score = 85.4 bits (202), Expect = 8e-16
Identities = 53/159 (33%), Positives = 71/159 (44%), Gaps = 32/159 (20%)
Query: 562 PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCD 621
P V+ + +CP+GY+R + C+DINEC LC C+NT GS+LC
Sbjct: 473 PRPASPVIENGQLECPQGYKRLNLTH-----CQDINECLTL-GLCKDAECVNTRGSYLCT 526
Query: 622 CDAGFEPSEDGTDCIDRRT-----GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXX 676
C G + C+ + G CYRSL G C
Sbjct: 527 CRPGLMLDPSRSRCVSDKAISMLQGLCYRSLGPGTC--------------------TLPL 566
Query: 677 XGHVTKAQCCCT-LGAAWGSECELCPAPGSPARLDLCTA 714
+TK CCC+ +G AWGSECE CP PG+ A ++C A
Sbjct: 567 AQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREICPA 605
Score = 84.2 bits (199), Expect = 2e-15
Identities = 54/125 (43%), Positives = 63/125 (50%), Gaps = 14/125 (11%)
Query: 747 DVDECAA---IP-GLC--APGRFRC-VCGPGY--RPAGEVCADVDECAVRPPPCDQ-LCH 796
DVDECA+ P GLC G F C C GY G C D+DECA P C +C
Sbjct: 930 DVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVCPSGVCT 988
Query: 797 NTDGSYDCL-CRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYE-K 853
NT GS+ C C GY G +C DVDECE +C C NT GSY+C C G++
Sbjct: 989 NTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLA 1048
Query: 854 RGDAC 858
G C
Sbjct: 1049 NGTVC 1053
Score = 78.6 bits (185), Expect = 9e-14
Identities = 43/106 (40%), Positives = 59/106 (55%), Gaps = 10/106 (9%)
Query: 761 GRFRCVCGPGYR----PAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 815
G + C C PGY A + C D++EC +P C C NT+GSY C C GY +
Sbjct: 786 GSYSCFCYPGYTLATSGATQECQDINECE-QPGVCSGGQCTNTEGSYHCECDQGYIMVRK 844
Query: 816 GANCRDVDECERDTHTCQQ-ICSNTEGSYEC-SCEDGYEKRGDACV 859
G +C+D++EC R TC C N+ GSY C +CE+GY + +CV
Sbjct: 845 G-HCQDINEC-RHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCV 888
Score = 70.1 bits (164), Expect = 3e-11
Identities = 31/75 (41%), Positives = 42/75 (56%), Gaps = 4/75 (5%)
Query: 202 CRNGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECRE---GGMVCRNGRCRNTVGSFRC 257
C NG C + Y C C +GF+ + CVDVNEC + ++C +G C NT GS+RC
Sbjct: 1622 CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC 1681
Query: 258 ECAPGYTLTADGRNC 272
C+PGY A +C
Sbjct: 1682 HCSPGYVAEAGPPHC 1696
Score = 67.7 bits (158), Expect = 2e-10
Identities = 37/93 (39%), Positives = 43/93 (46%), Gaps = 6/93 (6%)
Query: 461 PDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAE--GR 517
P G + A+EC + C NG C R GY C C GF CVDV+EC + G
Sbjct: 1605 PAGFEGLQAEECGI-LNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGP 1663
Query: 518 ASCTFR--CHNTAGSFRCTCPYGYAVAADGVHC 548
A C NT GS+RC C GY A HC
Sbjct: 1664 AVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHC 1696
Score = 65.3 bits (152), Expect = 9e-10
Identities = 48/134 (35%), Positives = 63/134 (47%), Gaps = 16/134 (11%)
Query: 365 CYDEWEAGRCHRARPL-QLARPECCC-SEGAAWG-RYCERCPAPDSAEFMRI----CQGG 417
CY G+C A PL +L E CC S GA WG C CP ++ + C G
Sbjct: 433 CYLNTVNGQC--ANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQG 490
Query: 418 MGRPNLT--QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
R NLT QD++EC + +C CVNT GS+ C C G +L P CV ++
Sbjct: 491 YKRLNLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISML 549
Query: 476 PRIC----GNGTCS 485
+C G GTC+
Sbjct: 550 QGLCYRSLGPGTCT 563
Score = 65.3 bits (152), Expect = 9e-10
Identities = 29/75 (38%), Positives = 42/75 (56%), Gaps = 4/75 (5%)
Query: 428 DECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC--ALDPRI-CGNGTC 484
+EC + + C GRCV + C+C +G+ L ++CVD +EC P + C +G C
Sbjct: 1614 EECGIL-NGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYC 1672
Query: 485 SNTRGGYECQCSPGF 499
NT G Y C CSPG+
Sbjct: 1673 ENTEGSYRCHCSPGY 1687
Score = 63.7 bits (148), Expect = 3e-09
Identities = 31/80 (38%), Positives = 43/80 (53%), Gaps = 7/80 (8%)
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTL--RENVCRDVDEC---SRPRPVCRNGTCE 208
+ECG C++G C Y C+C G+ L C DV+EC + P +C +G CE
Sbjct: 1614 EECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCE 1673
Query: 209 NLPGAYLCHCDDGF--KAGP 226
N G+Y CHC G+ +AGP
Sbjct: 1674 NTEGSYRCHCSPGYVAEAGP 1693
Score = 62.1 bits (144), Expect = 8e-09
Identities = 27/62 (43%), Positives = 35/62 (56%), Gaps = 4/62 (6%)
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQR----ICDHGDCRNTIGSYRCECKP 180
+CV + + C C G++L + C DV+EC D +C HG C NT GSYRC C P
Sbjct: 1626 RCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSP 1685
Query: 181 GY 182
GY
Sbjct: 1686 GY 1687
Score = 61.3 bits (142), Expect = 1e-08
Identities = 26/66 (39%), Positives = 33/66 (50%)
Query: 243 CRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC 302
C NGRC + C+C G+ L A C DV+ECD+L P + C NT G Y C
Sbjct: 1622 CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC 1681
Query: 303 SCGAGW 308
C G+
Sbjct: 1682 HCSPGY 1687
Score = 56.8 bits (131), Expect = 3e-07
Identities = 35/92 (38%), Positives = 40/92 (43%), Gaps = 10/92 (10%)
Query: 765 CVCGPGYRPA------GEVC-ADVDECAVRPPP-CDQ-LCHNTDGSYDCLCRTGYELDED 815
C G GY P G+ D DEC + P C C NT Y CLC G+ D
Sbjct: 1342 CPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDAS 1401
Query: 816 GANCRDVDECERDTHTCQQICSNTEGSYECSC 847
C D DEC+ D C NTEGS+ C C
Sbjct: 1402 HKKCEDHDECQ-DLACENGECVNTEGSFHCFC 1432
Score = 53.6 bits (123), Expect = 3e-06
Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Query: 134 ECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVD 193
+ CP GY+ +L C+D++EC +C +C NT GSY C C+PG L + R V
Sbjct: 484 QLECPQGYKRL-NLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVS 542
Query: 194 E 194
+
Sbjct: 543 D 543
Score = 52.4 bits (120), Expect = 7e-06
Identities = 39/140 (27%), Positives = 53/140 (37%), Gaps = 13/140 (9%)
Query: 452 ECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVD 511
ECP GY + C D +EC L +C + C NTRG Y C C PG P ++
Sbjct: 486 ECPQGYKRL-NLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRS----- 538
Query: 512 ECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDEC-VQEPRVCPHACENV 568
C +A + C+ + G CT P + C + + E CP
Sbjct: 539 RCVSDKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEA 598
Query: 569 VGSYICKCPEGYRRTSAPQD 588
CP G+ T A D
Sbjct: 599 FREI---CPAGHGYTYASSD 615
Score = 52.0 bits (119), Expect = 9e-06
Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 773 PAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECER---DT 829
PAG +EC + + C Y C C G++LD C DV+EC+
Sbjct: 1605 PAGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPA 1664
Query: 830 HTCQQ-ICSNTEGSYECSCEDGY 851
C C NTEGSY C C GY
Sbjct: 1665 VLCVHGYCENTEGSYRCHCSPGY 1687
Score = 51.6 bits (118), Expect = 1e-05
Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 7/65 (10%)
Query: 565 CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED---LCSGGVCINTDGSFLCD 621
C V Y C C EG++ +A AC D+NEC++ LC G C NT+GS+ C
Sbjct: 1627 CVRVREGYTCDCFEGFQLDAAHM----ACVDVNECDDLNGPAVLCVHGYCENTEGSYRCH 1682
Query: 622 CDAGF 626
C G+
Sbjct: 1683 CSPGY 1687
Score = 51.2 bits (117), Expect = 2e-05
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 9/113 (7%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDEC-SWGRPPCRGMAQCVNLPGAFECR 136
C P Q C GY+ N +H C+D++EC + G C+ A+CVN G++ C
Sbjct: 471 CPPRPASPVIENGQLECPQGYKRLNLTH-CQDINECLTLGL--CKD-AECVNTRGSYLCT 526
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVC 189
C PG L PS C V + + G C ++G C + + +C
Sbjct: 527 CRPGLMLDPSRSRC--VSDKAISML--QGLCYRSLGPGTCTLPLAQRITKQIC 575
Score = 50.8 bits (116), Expect = 2e-05
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 3/84 (3%)
Query: 60 PVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPP 119
P E +EC I+ C+ G C G+ C C G++ D C DV+EC P
Sbjct: 1605 PAGFEGLQAEECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGP 1663
Query: 120 CRGMAQ--CVNLPGAFECRCPPGY 141
C N G++ C C PGY
Sbjct: 1664 AVLCVHGYCENTEGSYRCHCSPGY 1687
Score = 50.0 bits (114), Expect = 4e-05
Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 2/78 (2%)
Query: 218 CDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE 277
C G+K C D+NEC G+ C++ C NT GS+ C C PG L C
Sbjct: 487 CPQGYKRLNLTHCQDINECLTLGL-CKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKA 545
Query: 278 CDELPHPCGRDGNP-SCT 294
L C R P +CT
Sbjct: 546 ISMLQGLCYRSLGPGTCT 563
Score = 48.8 bits (111), Expect = 8e-05
Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 4/83 (4%)
Query: 508 VDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDEC--VQEPRV-CPHA 564
+ +EC RC + C C G+ + A + C D++EC + P V C H
Sbjct: 1611 LQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHG 1670
Query: 565 -CENVVGSYICKCPEGYRRTSAP 586
CEN GSY C C GY + P
Sbjct: 1671 YCENTEGSYRCHCSPGYVAEAGP 1693
Score = 48.4 bits (110), Expect = 1e-04
Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 5/64 (7%)
Query: 290 NPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKEL--PYV-CAGGECRNFNGGYVCEC 344
N C GY C C G++L CVD +EC +L P V C G C N G Y C C
Sbjct: 1624 NGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHC 1683
Query: 345 PAGW 348
G+
Sbjct: 1684 SPGY 1687
Score = 47.6 bits (108), Expect = 2e-04
Identities = 44/152 (28%), Positives = 57/152 (37%), Gaps = 9/152 (5%)
Query: 4 NEEDQSCAGAVGVPQTKYLCCCSVGHAWGAP-CEACPPR-GSPAHTALCGEKPGEYINPV 61
N + CA + T+ CC SVG WG C CPPR SP E P Y
Sbjct: 436 NTVNGQCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQGYKRLN 495
Query: 62 TNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
+ I+EC + LCK C +T + C C G D + C S +
Sbjct: 496 LTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISM----LQ 550
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
G+ C G C P R+T + C V
Sbjct: 551 GL--CYRSLGPGTCTLPLAQRITKQICCCSRV 580
Score = 44.0 bits (99), Expect = 0.002
Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 13/115 (11%)
Query: 177 ECKPGYT-LRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVN 234
EC GY L C+D++EC +C++ C N G+YLC C G P+ CV
Sbjct: 486 ECPQGYKRLNLTHCQDINECLT-LGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVS-- 542
Query: 235 ECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV-----DECDELPHP 284
+ + G C ++G C +T C V EC++ P P
Sbjct: 543 ---DKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLP 594
Score = 42.7 bits (96), Expect = 0.005
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 10 CAGAVGVPQTKYL-CCCSVGHAWGAPCEACPPRGSPAHTALC 50
C+ + +T Y CCC G AW C CPPR S + LC
Sbjct: 1474 CSEPLRGHRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLC 1515
Score = 41.5 bits (93), Expect = 0.012
Identities = 21/54 (38%), Positives = 25/54 (46%), Gaps = 1/54 (1%)
Query: 767 CGPGYRPAGEV-CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
C GY+ C D++EC D C NT GSY C CR G LD + C
Sbjct: 487 CPQGYKRLNLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRC 540
Score = 39.9 bits (89), Expect = 0.038
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 14/84 (16%)
Query: 749 DECAAIPGLCAPGR-------FRCVCGPGYR--PAGEVCADVDECAVRPPPC----DQLC 795
+EC + G C GR + C C G++ A C DV+EC P C
Sbjct: 1614 EECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYC 1672
Query: 796 HNTDGSYDCLCRTGYELDEDGANC 819
NT+GSY C C GY + +C
Sbjct: 1673 ENTEGSYRCHCSPGYVAEAGPPHC 1696
Score = 39.1 bits (87), Expect = 0.066
Identities = 14/23 (60%), Positives = 17/23 (73%)
Query: 436 VCVGGRCVNTDGSFRCECPDGYV 458
+CV G C NT+GS+RC C GYV
Sbjct: 1666 LCVHGYCENTEGSYRCHCSPGYV 1688
Score = 34.7 bits (76), Expect = 1.4
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 8/69 (11%)
Query: 784 CAVRPP-PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI-CSNTEG 841
CA PP P + N G +C GY+ + +C+D++EC C+ C NT G
Sbjct: 468 CAPCPPRPASPVIEN--GQLEC--PQGYKR-LNLTHCQDINEC-LTLGLCKDAECVNTRG 521
Query: 842 SYECSCEDG 850
SY C+C G
Sbjct: 522 SYLCTCRPG 530
Score = 33.9 bits (74), Expect = 2.5
Identities = 12/32 (37%), Positives = 15/32 (46%)
Query: 328 CAGGECRNFNGGYVCECPAGWRFDKTAAVCVD 359
C G C GY C+C G++ D CVD
Sbjct: 1622 CENGRCVRVREGYTCDCFEGFQLDAAHMACVD 1653
>Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein.
Length = 1821
Score = 444 bits (1095), Expect = e-124
Identities = 277/800 (34%), Positives = 372/800 (46%), Gaps = 94/800 (11%)
Query: 61 VTNETKPIDECDI-MPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPP 119
VT T ID C +C PGTC + P G++C C GY+ + C D +EC R P
Sbjct: 838 VTLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECL--RDP 895
Query: 120 CRGMAQCVNLPGAFECRCPPGYRLTPS--LDECEDVDECGDQRICDHGDCRNTIGSYRCE 177
C+G +C+N G++ C C PGY L S EC+D++EC +C G C NT GSY CE
Sbjct: 896 CQGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCE 955
Query: 178 CKPGYTL-RENVCRDVDECSRPRPVCRNGTCENLPGAYLC-HCDDGFKAGPNNDCVDVNE 235
C GY + R+ C+D++EC P C +G C N PG+Y C C++G++ G + CVDVNE
Sbjct: 956 CDQGYIMVRKGHCQDINECRHPG-TCPDGRCVNSPGSYTCLACEEGYR-GQSGSCVDVNE 1013
Query: 236 CREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC-DELPHPCGRDGNPSCT 294
C G VC +G+C N GSFRC C GY +T+D + C+DVDEC P G C
Sbjct: 1014 CLTPG-VCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGL-----CL 1067
Query: 295 NTNGGYECS-CGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVC-ECPAGWRF 350
NT G + CS C G+ + G C D DEC P VC G C N G + C +C G+R
Sbjct: 1068 NTEGSFACSACENGYWVNEDGTACEDLDECA-FPGVCPSGVCTNTAGSFSCKDCDGGYRP 1126
Query: 351 DKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
C D DE E P+ C G C+ +
Sbjct: 1127 SPLGDSCED------VDECED-------------PQSSCLGGE-----CKNTVG----SY 1158
Query: 411 MRICQGGMGRPNLT--QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
+C G N T +D++EC G C+N+ GSF C C G+V A G SC D
Sbjct: 1159 QCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQD 1218
Query: 469 ADECAL-DPRICGNGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAE-GRASC-TFRC 524
DECA DP C G C NT G + C C GF P+ CVD+DEC + G C T++C
Sbjct: 1219 VDECATTDP--CVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKC 1276
Query: 525 HNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYR 581
N+ GS+RC C G+ +A +G C DIDEC + H C+N GS+ C C +G+
Sbjct: 1277 ENSPGSYRCVLGCQPGFHMAPNG-DCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFE 1335
Query: 582 RTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP--SEDGTDCIDRR 639
+ + D C D+NECE +C +C N +GSFLC C + E +++G C R
Sbjct: 1336 ISPSGWD----CVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEG-HCRPRG 1390
Query: 640 TGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECEL 699
G S + T+A+CCCT GA WG C+L
Sbjct: 1391 AGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGATWGDACDL 1450
Query: 700 CPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAI-PGLC 758
CP+ S ++C + ++ D DEC PGLC
Sbjct: 1451 CPSEDSAEFSEICPS-------------GKGYIPVEGAWTFGQTMYTDADECVIFGPGLC 1497
Query: 759 APGR-------FRCVCGPG--YRPAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRT 808
GR + C+C PG Y + + C D DEC + C+ C NT+GS+ C C
Sbjct: 1498 PNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSP 1555
Query: 809 GYELDEDGANCRDVDECERD 828
LD C + D
Sbjct: 1556 PLTLDLSQQRCMNSTSSTED 1575
Score = 279 bits (685), Expect = 2e-74
Identities = 176/538 (32%), Positives = 238/538 (44%), Gaps = 54/538 (10%)
Query: 50 CGEKPGEYI-NPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR 108
C + G Y +P+ + + +DEC+ C G C +T +QC C G++ N + +C
Sbjct: 1117 CKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGT-VCE 1175
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCR 168
DV+EC G C +C+N G+F C C PG+ C+DVDEC C G C
Sbjct: 1176 DVNEC-MGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCV 1234
Query: 169 NTIGSYRCECKPGY--TLRENVCRDVDEC-SRPRPVCRNGTCENLPGAYLC--HCDDGFK 223
NT GS+ C C+ G+ + C D+DEC PVC CEN PG+Y C C GF
Sbjct: 1235 NTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFH 1294
Query: 224 AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPH 283
PN DC+D++EC M +G C NT GSFRC C G+ ++ G +C DV+EC+ +
Sbjct: 1295 MAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLA 1354
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGEC--RNFNGGYV 341
CG C N G + C C + D +E Y G C R G +
Sbjct: 1355 VCGA---ALCENVEGSFLCLCAS----------DLEE-----YDAQEGHCRPRGAGGQSM 1396
Query: 342 CECPAGWRFDKTAAVCVDERKELCYDEWEA-GRCHRARPLQLARPECCCSEGAAWGRYCE 400
E P G D A R + CY + C + ECCC++GA WG C+
Sbjct: 1397 SEAPTG---DHAPA---PTRMD-CYSGQKGHAPCSSVLGRNTTQAECCCTQGATWGDACD 1449
Query: 401 RCPAPDSAEFMRICQGGMG----------RPNLTQDLDECRV-RPDVCVGGRCVNTDGSF 449
CP+ DSAEF IC G G + D DEC + P +C GRC+NT +
Sbjct: 1450 LCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGY 1509
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG-PDQTCV 508
C C G+ C D DEC C NG C NT G + C CSP T Q C+
Sbjct: 1510 VCLCNPGFHYDASHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSPPLTLDLSQQRCM 1567
Query: 509 DVDECAEGRASCTFR---CHNTAGSFRCTCPY-GYAVAADGVHCRDIDECVQEPRVCP 562
+ E C + C+ P G+ C+D Q+ +CP
Sbjct: 1568 NSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQDGKAWSQQCALCP 1625
Score = 274 bits (673), Expect = 7e-73
Identities = 207/676 (30%), Positives = 273/676 (40%), Gaps = 71/676 (10%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
++EC + P +C G C + F+C C+ GYE + C+DVDEC+ R C C+
Sbjct: 1011 VNEC-LTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECA-SRASCP-TGLCL 1067
Query: 128 NLPGAFECR-CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRC-ECKPGYTLR 185
N G+F C C GY + CED+DEC +C G C NT GS+ C +C GY
Sbjct: 1068 NTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPS 1127
Query: 186 E--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC 243
+ C DVDEC P+ C G C+N G+Y C C GF+ C DVNEC
Sbjct: 1128 PLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCA 1187
Query: 244 RNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS 303
+G C N+ GSF C CAPG+ G +C+DVDEC PC C NT G + C
Sbjct: 1188 PHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDEC-ATTDPC---VGGHCVNTEGSFNCL 1243
Query: 304 CGAGWK--LVGRRCVDRDECKEL-PYVCAGGECRNFNGGYVC--ECPAGWRFDKTAAVCV 358
C G++ CVD DEC++ VC +C N G Y C C G+ C+
Sbjct: 1244 CETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGD-CI 1302
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
D + C ++ G H C C +G C + E M G
Sbjct: 1303 D--IDECANDTMCG-SHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAA 1359
Query: 419 GRPNL--------TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDG-YVLAPDGLSCVDA 469
N+ DL+E + C R G E P G + AP + C
Sbjct: 1360 LCENVEGSFLCLCASDLEEYDAQEGHC---RPRGAGGQSMSEAPTGDHAPAPTRMDCYSG 1416
Query: 470 DECALDPRICGNGTCSNTRG----GYECQCSPGFTQGPDQTCVDVDEC-AEGRASCTFRC 524
+ G+ CS+ G EC C+ G T G C D C +E A + C
Sbjct: 1417 QK--------GHAPCSSVLGRNTTQAECCCTQGATWG--DAC---DLCPSEDSAEFSEIC 1463
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECV-QEPRVCPHA-CENVVGSYICKCPEGYRR 582
+ G P A D DECV P +CP+ C N V Y+C C G+
Sbjct: 1464 PSGKGYI----PVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHY 1519
Query: 583 TSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGT 642
+ S CED +EC Q+ C G C+NT+GSF C C +D
Sbjct: 1520 DA----SHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSPPL--------TLDLSQQR 1565
Query: 643 CYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGH-VTKAQCCCTLGAAWGSECELCP 701
C S S P+ GH T +CCC G AW +C LCP
Sbjct: 1566 CMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQDGKAWSQQCALCP 1625
Query: 702 APGSPARLDLCTAVNL 717
S LC +
Sbjct: 1626 PRSSEVYAQLCNVARI 1641
Score = 225 bits (550), Expect = 5e-58
Identities = 154/463 (33%), Positives = 200/463 (43%), Gaps = 46/463 (9%)
Query: 424 TQDLDECRV-RPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRIC-GN 481
T +D C +VC G CVN +RC C GY L P C D +EC DP C G
Sbjct: 842 TPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDP--CQGK 899
Query: 482 GTCSNTRGGYECQCSPGFT---QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYG 538
G C N G Y C C PG+T G Q C D++EC + +C NT GS+ C C G
Sbjct: 900 GRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQG 959
Query: 539 YAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYIC-KCPEGYRRTSAPQDSENACEDI 596
Y + G HC+DI+EC + P CP C N GSY C C EGYR S +C D+
Sbjct: 960 YIMVRKG-HCQDINEC-RHPGTCPDGRCVNSPGSYTCLACEEGYRGQSG------SCVDV 1011
Query: 597 NECEEQEDLCSGGVCINTDGSFLCDCDAGFEPS------EDGTDCIDRR---TGTCYRSL 647
NEC +C+ G C N +GSF C C+ G+E + +D +C R TG C +
Sbjct: 1012 NECLTP-GVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTE 1070
Query: 648 VSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECE--LCPAP-- 703
S C G C T G+ +C+ P+P
Sbjct: 1071 GSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLG 1130
Query: 704 GSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLD--VFADVDEC-----AAIPG 756
S +D C + + V DV+EC A G
Sbjct: 1131 DSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHG 1190
Query: 757 LC--APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
C + G F C+C PG+ A G C DVDECA P C NT+GS++CLC TG++
Sbjct: 1191 ECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQP 1250
Query: 813 DEDGANCRDVDECE--RDTHTCQQICSNTEGSYEC--SCEDGY 851
+ C D+DECE D C N+ GSY C C+ G+
Sbjct: 1251 SPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGF 1293
Score = 183 bits (446), Expect = 2e-45
Identities = 133/418 (31%), Positives = 172/418 (41%), Gaps = 37/418 (8%)
Query: 464 LSCVDADECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCT 521
LS D CA +CG GTC N GY C CSPG+ P Q C D +EC
Sbjct: 840 LSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCQGK 899
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGV--HCRDIDECVQEPRVCPHA-CENVVGSYICKCPE 578
RC N GS+ C C GY +A G C+DI+EC ++P VC C N GSY C+C +
Sbjct: 900 GRCINRVGSYSCFCYPGYTLATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECDQ 958
Query: 579 GYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC-DCDAGFEPSE----DGT 633
GY + C+DINEC C G C+N+ GS+ C C+ G+ D
Sbjct: 959 GYIMVR-----KGHCQDINECRHP-GTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVN 1012
Query: 634 DCIDRRT---GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLG 690
+C+ G C S RC E T C T G
Sbjct: 1013 ECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPT-GLCLNTEG 1071
Query: 691 AAWGSECE---LCPAPGSPAR-LDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXL---D 743
+ S CE G+ LD C + P D
Sbjct: 1072 SFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGD 1131
Query: 744 VFADVDEC-----AAIPGLC--APGRFRCVCGPGYRPA-GEVCADVDECAVRPPPCDQ-L 794
DVDEC + + G C G ++C+C G++ A G VC DV+EC
Sbjct: 1132 SCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGE 1191
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
C N+ GS+ CLC G+ E G +C+DVDEC C NTEGS+ C CE G++
Sbjct: 1192 CLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQ 1249
Score = 120 bits (289), Expect = 2e-26
Identities = 154/569 (27%), Positives = 205/569 (36%), Gaps = 68/569 (11%)
Query: 31 WGAP-CEACPPRGSP-AHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPT 88
+G P C SP ++ + G +PG ++ P + IDEC G C +T
Sbjct: 1266 YGDPVCGTWKCENSPGSYRCVLGCQPGFHMAP-NGDCIDIDECANDTMCGSHGFCDNTDG 1324
Query: 89 GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAF--------------E 134
F+C CD G+E + C DV+EC C G A C N+ G+F E
Sbjct: 1325 SFRCLCDQGFEISPSGWDCVDVNECELMLAVC-GAALCENVEGSFLCLCASDLEEYDAQE 1383
Query: 135 CRCPPGYRLTPSLDECEDVDECGDQRICD-------HGDCRNTIG----SYRCECKPGYT 183
C P S+ E D D H C + +G C C G T
Sbjct: 1384 GHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGAT 1443
Query: 184 LRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGM 241
+ ++C D +C +G Y+ + + G D +EC G
Sbjct: 1444 WGDACDLCPSEDSAEFSE-ICPSGK------GYI-PVEGAWTFGQTM-YTDADECVIFGP 1494
Query: 242 -VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGY 300
+C NGRC NTV + C C PG+ A + C D DEC +L C N C NT G +
Sbjct: 1495 GLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQDLA--CE---NGECVNTEGSF 1549
Query: 301 E--CSCGAGWKLVGRRCVDRDECKE-LP-YVCAGGECRNFNGGYVCECPA-GWRFDKTAA 355
CS L +RC++ E LP + C VC P G R T
Sbjct: 1550 HCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTEC 1609
Query: 356 VCVDER--KELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRI 413
C D + + C A+ +AR E G + E P PD +
Sbjct: 1610 CCQDGKAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPDDLHYSIY 1669
Query: 414 CQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRC-----ECPDGYVLA----PDGL 464
G N D G + E YV + P G
Sbjct: 1670 GPDGAPFYNYLGPEDTVPEPAFPNTAGHSADRTPILESPLQPSELQPHYVASHPEPPAGF 1729
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAE--GRASCT 521
+ A+EC + C NG C R GY C C GF CVDV+EC + G A
Sbjct: 1730 EGLQAEECGI-LNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLC 1788
Query: 522 FR--CHNTAGSFRCTCPYGYAVAADGVHC 548
C NT GS+RC C GY A HC
Sbjct: 1789 VHGYCENTEGSYRCHCSPGYVAEAGPPHC 1817
Score = 96.7 bits (230), Expect = 3e-19
Identities = 53/125 (42%), Positives = 67/125 (53%), Gaps = 14/125 (11%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHN 797
DV+EC PG+CA G+ FRC C GY + C DVDECA R LC N
Sbjct: 1010 DVNECLT-PGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLN 1068
Query: 798 TDGSYDC-LCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC-SCEDGYEKR- 854
T+GS+ C C GY ++EDG C D+DEC +C+NT GS+ C C+ GY
Sbjct: 1069 TEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSP 1128
Query: 855 -GDAC 858
GD+C
Sbjct: 1129 LGDSC 1133
Score = 92.3 bits (219), Expect = 7e-18
Identities = 51/124 (41%), Positives = 66/124 (53%), Gaps = 14/124 (11%)
Query: 747 DVDECAAIPGLC-------APGRFRCV-CGPGYRPAGEVCADVDECAVRPPPCDQ-LCHN 797
D++EC PG C +PG + C+ C GYR C DV+EC + P C C N
Sbjct: 970 DINECRH-PGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNEC-LTPGVCAHGKCTN 1027
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGY--EKR 854
+GS+ C C GYE+ D C+DVDEC +C NTEGS+ CS CE+GY +
Sbjct: 1028 LEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNED 1087
Query: 855 GDAC 858
G AC
Sbjct: 1088 GTAC 1091
Score = 87.0 bits (206), Expect = 3e-16
Identities = 47/119 (39%), Positives = 65/119 (54%), Gaps = 14/119 (11%)
Query: 747 DVDECAA----IPGLCA--PGRFRCVCGPGYRPAGE--VCADVDECA-VRPPPCDQ-LCH 796
DVDECA + G C G F C+C G++P+ E C D+DEC P C C
Sbjct: 1218 DVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCE 1277
Query: 797 NTDGSYDCL--CRTGYELDEDGANCRDVDECERDTHT-CQQICSNTEGSYECSCEDGYE 852
N+ GSY C+ C+ G+ + +G +C D+DEC DT C NT+GS+ C C+ G+E
Sbjct: 1278 NSPGSYRCVLGCQPGFHMAPNG-DCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFE 1335
Score = 87.0 bits (206), Expect = 3e-16
Identities = 52/149 (34%), Positives = 68/149 (45%), Gaps = 13/149 (8%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVT-----NE 64
C+ +G T+ CCC+ G WG C+ CP S + +C G YI PV +
Sbjct: 1423 CSSVLGRNTTQAECCCTQGATWGDACDLCPSEDSAEFSEICPSGKG-YI-PVEGAWTFGQ 1480
Query: 65 T--KPIDECDIM-PQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
T DEC I P LC G C +T G+ C C+ G+ +D + C D DEC C
Sbjct: 1481 TMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQ--DLACE 1538
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDEC 150
+CVN G+F C C P L S C
Sbjct: 1539 N-GECVNTEGSFHCFCSPPLTLDLSQQRC 1566
Score = 85.8 bits (203), Expect = 6e-16
Identities = 65/193 (33%), Positives = 83/193 (43%), Gaps = 18/193 (9%)
Query: 246 GRCR-NTVGSFRCECA-PGYTLTADGRNCRDVDEC--DELPHPCG-RDGNPSCTNTNGGY 300
GRC NTV +CA P LT C V L PC R +P N G
Sbjct: 552 GRCYLNTVNG---QCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIEN--GQL 606
Query: 301 ECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
EC G +L C D +EC L +C EC N G Y+C C G D + + CV +
Sbjct: 607 ECPQGYK-RLNLTHCQDINECLTLG-LCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSD 664
Query: 361 R-----KELCYDEWEAGRCHRARPLQLARPECCCSE-GAAWGRYCERCPAPDSAEFMRIC 414
+ + LCY G C ++ + CCCS G AWG CE+CP P + F IC
Sbjct: 665 KAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREIC 724
Query: 415 QGGMGRPNLTQDL 427
G G + D+
Sbjct: 725 PAGHGYTYASSDI 737
Score = 85.8 bits (203), Expect = 6e-16
Identities = 44/102 (43%), Positives = 57/102 (55%), Gaps = 9/102 (8%)
Query: 759 APGRFRCV--CGPGYR--PAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYEL 812
+PG +RCV C PG+ P G+ C D+DECA C C NTDGS+ CLC G+E+
Sbjct: 1279 SPGSYRCVLGCQPGFHMAPNGD-CIDIDECA-NDTMCGSHGFCDNTDGSFRCLCDQGFEI 1336
Query: 813 DEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEK 853
G +C DV+ECE C +C N EGS+ C C E+
Sbjct: 1337 SPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEE 1378
Score = 85.4 bits (202), Expect = 8e-16
Identities = 53/159 (33%), Positives = 71/159 (44%), Gaps = 32/159 (20%)
Query: 562 PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCD 621
P V+ + +CP+GY+R + C+DINEC LC C+NT GS+LC
Sbjct: 594 PRPASPVIENGQLECPQGYKRLNLTH-----CQDINECLTL-GLCKDAECVNTRGSYLCT 647
Query: 622 CDAGFEPSEDGTDCIDRRT-----GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXX 676
C G + C+ + G CYRSL G C
Sbjct: 648 CRPGLMLDPSRSRCVSDKAISMLQGLCYRSLGPGTC--------------------TLPL 687
Query: 677 XGHVTKAQCCCT-LGAAWGSECELCPAPGSPARLDLCTA 714
+TK CCC+ +G AWGSECE CP PG+ A ++C A
Sbjct: 688 AQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREICPA 726
Score = 84.2 bits (199), Expect = 2e-15
Identities = 54/125 (43%), Positives = 63/125 (50%), Gaps = 14/125 (11%)
Query: 747 DVDECAA---IP-GLC--APGRFRC-VCGPGY--RPAGEVCADVDECAVRPPPCDQ-LCH 796
DVDECA+ P GLC G F C C GY G C D+DECA P C +C
Sbjct: 1051 DVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVCPSGVCT 1109
Query: 797 NTDGSYDCL-CRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYE-K 853
NT GS+ C C GY G +C DVDECE +C C NT GSY+C C G++
Sbjct: 1110 NTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLA 1169
Query: 854 RGDAC 858
G C
Sbjct: 1170 NGTVC 1174
Score = 78.6 bits (185), Expect = 9e-14
Identities = 43/106 (40%), Positives = 59/106 (55%), Gaps = 10/106 (9%)
Query: 761 GRFRCVCGPGYR----PAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 815
G + C C PGY A + C D++EC +P C C NT+GSY C C GY +
Sbjct: 907 GSYSCFCYPGYTLATSGATQECQDINECE-QPGVCSGGQCTNTEGSYHCECDQGYIMVRK 965
Query: 816 GANCRDVDECERDTHTCQQ-ICSNTEGSYEC-SCEDGYEKRGDACV 859
G +C+D++EC R TC C N+ GSY C +CE+GY + +CV
Sbjct: 966 G-HCQDINEC-RHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCV 1009
Score = 65.3 bits (152), Expect = 9e-10
Identities = 48/134 (35%), Positives = 63/134 (47%), Gaps = 16/134 (11%)
Query: 365 CYDEWEAGRCHRARPL-QLARPECCC-SEGAAWG-RYCERCPAPDSAEFMRI----CQGG 417
CY G+C A PL +L E CC S GA WG C CP ++ + C G
Sbjct: 554 CYLNTVNGQC--ANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQG 611
Query: 418 MGRPNLT--QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
R NLT QD++EC + +C CVNT GS+ C C G +L P CV ++
Sbjct: 612 YKRLNLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISML 670
Query: 476 PRIC----GNGTCS 485
+C G GTC+
Sbjct: 671 QGLCYRSLGPGTCT 684
Score = 56.8 bits (131), Expect = 3e-07
Identities = 35/92 (38%), Positives = 40/92 (43%), Gaps = 10/92 (10%)
Query: 765 CVCGPGYRPA------GEVC-ADVDECAVRPPP-CDQ-LCHNTDGSYDCLCRTGYELDED 815
C G GY P G+ D DEC + P C C NT Y CLC G+ D
Sbjct: 1463 CPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDAS 1522
Query: 816 GANCRDVDECERDTHTCQQICSNTEGSYECSC 847
C D DEC+ D C NTEGS+ C C
Sbjct: 1523 HKKCEDHDECQ-DLACENGECVNTEGSFHCFC 1553
Score = 53.6 bits (123), Expect = 3e-06
Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Query: 134 ECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVD 193
+ CP GY+ +L C+D++EC +C +C NT GSY C C+PG L + R V
Sbjct: 605 QLECPQGYKRL-NLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVS 663
Query: 194 E 194
+
Sbjct: 664 D 664
Score = 52.4 bits (120), Expect = 7e-06
Identities = 39/140 (27%), Positives = 53/140 (37%), Gaps = 13/140 (9%)
Query: 452 ECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVD 511
ECP GY + C D +EC L +C + C NTRG Y C C PG P ++
Sbjct: 607 ECPQGYKRL-NLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRS----- 659
Query: 512 ECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDEC-VQEPRVCPHACENV 568
C +A + C+ + G CT P + C + + E CP
Sbjct: 660 RCVSDKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEA 719
Query: 569 VGSYICKCPEGYRRTSAPQD 588
CP G+ T A D
Sbjct: 720 FREI---CPAGHGYTYASSD 736
Score = 52.0 bits (119), Expect = 9e-06
Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 773 PAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECER---DT 829
PAG +EC + + C Y C C G++LD C DV+EC+
Sbjct: 1726 PAGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPA 1785
Query: 830 HTCQQ-ICSNTEGSYECSCEDGY 851
C C NTEGSY C C GY
Sbjct: 1786 VLCVHGYCENTEGSYRCHCSPGY 1808
Score = 51.6 bits (118), Expect = 1e-05
Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 7/65 (10%)
Query: 565 CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED---LCSGGVCINTDGSFLCD 621
C V Y C C EG++ +A AC D+NEC++ LC G C NT+GS+ C
Sbjct: 1748 CVRVREGYTCDCFEGFQLDAAHM----ACVDVNECDDLNGPAVLCVHGYCENTEGSYRCH 1803
Query: 622 CDAGF 626
C G+
Sbjct: 1804 CSPGY 1808
Score = 51.2 bits (117), Expect = 2e-05
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 9/113 (7%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDEC-SWGRPPCRGMAQCVNLPGAFECR 136
C P Q C GY+ N +H C+D++EC + G C+ A+CVN G++ C
Sbjct: 592 CPPRPASPVIENGQLECPQGYKRLNLTH-CQDINECLTLGL--CKD-AECVNTRGSYLCT 647
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVC 189
C PG L PS C V + + G C ++G C + + +C
Sbjct: 648 CRPGLMLDPSRSRC--VSDKAISML--QGLCYRSLGPGTCTLPLAQRITKQIC 696
Score = 50.0 bits (114), Expect = 4e-05
Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 2/78 (2%)
Query: 218 CDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE 277
C G+K C D+NEC G+ C++ C NT GS+ C C PG L C
Sbjct: 608 CPQGYKRLNLTHCQDINECLTLGL-CKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKA 666
Query: 278 CDELPHPCGRDGNP-SCT 294
L C R P +CT
Sbjct: 667 ISMLQGLCYRSLGPGTCT 684
Score = 48.8 bits (111), Expect = 8e-05
Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 4/83 (4%)
Query: 508 VDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDEC--VQEPRV-CPHA 564
+ +EC RC + C C G+ + A + C D++EC + P V C H
Sbjct: 1732 LQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHG 1791
Query: 565 -CENVVGSYICKCPEGYRRTSAP 586
CEN GSY C C GY + P
Sbjct: 1792 YCENTEGSYRCHCSPGYVAEAGP 1814
Score = 47.6 bits (108), Expect = 2e-04
Identities = 44/152 (28%), Positives = 57/152 (37%), Gaps = 9/152 (5%)
Query: 4 NEEDQSCAGAVGVPQTKYLCCCSVGHAWGAP-CEACPPR-GSPAHTALCGEKPGEYINPV 61
N + CA + T+ CC SVG WG C CPPR SP E P Y
Sbjct: 557 NTVNGQCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQGYKRLN 616
Query: 62 TNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
+ I+EC + LCK C +T + C C G D + C S +
Sbjct: 617 LTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISM----LQ 671
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
G+ C G C P R+T + C V
Sbjct: 672 GL--CYRSLGPGTCTLPLAQRITKQICCCSRV 701
Score = 45.6 bits (103), Expect = 8e-04
Identities = 18/33 (54%), Positives = 22/33 (66%), Gaps = 1/33 (3%)
Query: 19 TKYLCCCS-VGHAWGAPCEACPPRGSPAHTALC 50
TK +CCCS VG AWG+ CE CP G+ A +C
Sbjct: 692 TKQICCCSRVGKAWGSECEKCPLPGTEAFREIC 724
Score = 44.0 bits (99), Expect = 0.002
Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 13/115 (11%)
Query: 177 ECKPGYT-LRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVN 234
EC GY L C+D++EC +C++ C N G+YLC C G P+ CV
Sbjct: 607 ECPQGYKRLNLTHCQDINECLT-LGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVS-- 663
Query: 235 ECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV-----DECDELPHP 284
+ + G C ++G C +T C V EC++ P P
Sbjct: 664 ---DKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLP 715
Score = 42.3 bits (95), Expect = 0.007
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 10 CAGAVGVPQTKYL-CCCSVGHAWGAPCEACPPRGSPAHTALC 50
C+ + +T Y CCC G AW C CPPR S + LC
Sbjct: 1595 CSEPLRGHRTTYTECCCQDGKAWSQQCALCPPRSSEVYAQLC 1636
Score = 41.5 bits (93), Expect = 0.012
Identities = 21/54 (38%), Positives = 25/54 (46%), Gaps = 1/54 (1%)
Query: 767 CGPGYRPAGEV-CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
C GY+ C D++EC D C NT GSY C CR G LD + C
Sbjct: 608 CPQGYKRLNLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRC 661
Score = 39.9 bits (89), Expect = 0.038
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 14/84 (16%)
Query: 749 DECAAIPGLCAPGR-------FRCVCGPGYR--PAGEVCADVDECAVRPPPC----DQLC 795
+EC + G C GR + C C G++ A C DV+EC P C
Sbjct: 1735 EECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYC 1793
Query: 796 HNTDGSYDCLCRTGYELDEDGANC 819
NT+GSY C C GY + +C
Sbjct: 1794 ENTEGSYRCHCSPGYVAEAGPPHC 1817
Score = 34.7 bits (76), Expect = 1.4
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 8/69 (11%)
Query: 784 CAVRPP-PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI-CSNTEG 841
CA PP P + N G +C GY+ + +C+D++EC C+ C NT G
Sbjct: 589 CAPCPPRPASPVIEN--GQLEC--PQGYKR-LNLTHCQDINEC-LTLGLCKDAECVNTRG 642
Query: 842 SYECSCEDG 850
SY C+C G
Sbjct: 643 SYLCTCRPG 651
>AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming growth
factor-beta binding protein 4L protein.
Length = 1624
Score = 412 bits (1015), Expect = e-114
Identities = 230/585 (39%), Positives = 292/585 (49%), Gaps = 60/585 (10%)
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLP 130
C PQ+C PG C P+G+ C CD G+ C DVDEC PPC +C N P
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSP 607
Query: 131 GAFECRCPPGYRLTPSLDECEDVDECGDQRI---CDHGDCRNTIGSYRCECKPGYTLREN 187
G+F C C PG+R P EC DVDEC R+ CD G C NT GS+ C C GY +
Sbjct: 608 GSFRCVCGPGFRAGPRAAECLDVDEC--HRVPPPCDLGRCENTPGSFLCVCPAGYQAAPH 665
Query: 188 --VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN 245
C+DVDEC++ +C G C+NLPG++ C C GF+ + DV+EC + C
Sbjct: 666 GASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEE--DVDECAQEPPPCGP 723
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
GRC NT GSF C C G+ G C+DVDEC P PC C NT G ++C C
Sbjct: 724 GRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG---RCENTEGSFQCVCP 780
Query: 306 AGWK--LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCE-CPAGWRFDKTAAVCVDERK 362
G++ G C D DEC E C G EC N G + C CP+G + VDE
Sbjct: 781 MGFQPNAAGSECEDVDEC-ENHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDE-- 837
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPN 422
C P C +EG+ C P + GRP
Sbjct: 838 -----------CSSGAPPCGPHGHCTNTEGSF---RCSCAPG---------YRAPSGRPG 874
Query: 423 LTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGN 481
D++EC + D C G C+NTDGSF C C GY P G SC+D DEC+ + +C +
Sbjct: 875 PCADVNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS-EEDLCQS 932
Query: 482 GTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAE-GRASC-TFRCHNTAGSFRCT--CP 536
G C+NT G +EC C PG GPD +C+DVDEC E G A C + RC N+ GS+RC C
Sbjct: 933 GICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCD 992
Query: 537 YGYAVAADGVHCRDIDECVQ-EPRVC-PHACENVVGSYIC--KCPEGYRRTSAPQDSENA 592
GY +G C D+DEC + P +C CEN GSY C C GY+ T
Sbjct: 993 PGYHAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPG-----GG 1046
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C+D++EC + + VC N GSF C CD G+E + DG C+D
Sbjct: 1047 CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD 1091
Score = 399 bits (983), Expect = e-110
Identities = 228/607 (37%), Positives = 296/607 (48%), Gaps = 55/607 (9%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C G ++P +DEC +P C PG C ++P F+C C G+ + C D
Sbjct: 570 CACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLD 629
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQ-RICDHGDCR 168
VDEC PPC + +C N PG+F C CP GY+ P C+DVDEC +C G C+
Sbjct: 630 VDECHRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACK 688
Query: 169 NTIGSYRCECKPGYTLRENVC-RDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA-GP 226
N GS+RC C G+ R + C DVDEC++ P C G C+N G++ C C GF++ GP
Sbjct: 689 NLPGSFRCVCPAGF--RGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGP 746
Query: 227 NNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C DV+EC C GRC NT GSF+C C G+ A G C DVDEC+ G
Sbjct: 747 GAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNAAGSECEDVDECENHLACPG 806
Query: 287 RDGNPSCTNTNGGYEC-SCGAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCEC 344
++ C N+ G ++C +C +G L RC D DEC C G C N G + C C
Sbjct: 807 QE----CVNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSC 862
Query: 345 PAGWRFDK-TAAVCVDERKELCYDE-WEAGRCHRARPLQLARPECCCSEGAAWGRYCERC 402
G+R C D + L D + G C C C+ G
Sbjct: 863 APGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTD----GSFACTCAPGYR-------- 910
Query: 403 PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPD 462
P P A + + DEC D+C G C NTDGSF C CP G+ PD
Sbjct: 911 PGPRGASCLDV--------------DECS-EEDLCQSGICTNTDGSFECICPPGHRAGPD 955
Query: 463 GLSCVDADEC-ALDPRICGNGTCSNTRGGYEC--QCSPGFTQGPDQTCVDVDECAE-GRA 518
SC+D DEC P +CG+ C N+ G Y C C PG+ GP+ TC DVDEC E G
Sbjct: 956 LASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPE 1015
Query: 519 SC-TFRCHNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYIC 574
C RC NT GS+RCT C GY G C+D+DEC HA C+N+ GS+ C
Sbjct: 1016 ICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNRSFCGAHAVCQNLPGSFQC 1074
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTD 634
C +GY +D + C D+NECE + +C +C N +GSFLC C E + T
Sbjct: 1075 LCDQGY---EGARDGRH-CVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTG 1130
Query: 635 -CIDRRT 640
C+ RT
Sbjct: 1131 RCVPPRT 1137
Score = 380 bits (936), Expect = e-105
Identities = 279/815 (34%), Positives = 349/815 (42%), Gaps = 104/815 (12%)
Query: 34 PCEACPPRGSP-AHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQC 92
PC SP + +CG PG P E +DEC +P C G C +TP F C
Sbjct: 597 PCAPGRCENSPGSFRCVCG--PGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLC 654
Query: 93 GCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECED 152
C GY+ C+DVDEC+ C G C NLPG+F C CP G+R S E ED
Sbjct: 655 VCPAGYQAAPHGASCQDVDECTQSPGLC-GRGACKNLPGSFRCVCPAGFR--GSACE-ED 710
Query: 153 VDECGDQRI-CDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCEN 209
VDEC + C G C NT GS+ C C G+ R C+DVDEC+R P C G CEN
Sbjct: 711 VDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCEN 770
Query: 210 LPGAYLCHCDDGFKAGP-NNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTAD 268
G++ C C GF+ ++C DV+EC E + C C N+ GSF+C P
Sbjct: 771 TEGSFQCVCPMGFQPNAAGSECEDVDEC-ENHLACPGQECVNSPGSFQCRACPSGHHLHR 829
Query: 269 GRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR---CVDRDECKELP 325
GR C DVDEC PCG G+ CTNT G + CSC G++ R C D +EC E
Sbjct: 830 GR-CTDVDECSSGAPPCGPHGH--CTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGD 886
Query: 326 YVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARP 385
+ GEC N +G + C C G+R A C+D + D ++G C
Sbjct: 887 FCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTD----GSF 942
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVR-PDVCVGGRCVN 444
EC C G G PD A + D+DECR R P +C RC N
Sbjct: 943 ECICPPGHRAG--------PDLASCL--------------DVDECRERGPALCGSQRCEN 980
Query: 445 TDGSFRC--ECPDGYVLAPDGLSCVDADECA-LDPRICGNGTCSNTRGGYECQ--CSPGF 499
+ GS+RC +C GY P+G +C D DEC P ICG C NT G Y C C PG+
Sbjct: 981 SPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGY 1039
Query: 500 TQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQE 557
P C DVDEC R+ C C N GSF+C C GY A DG HC D++EC
Sbjct: 1040 QPTPGGGCQDVDEC-RNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETL 1098
Query: 558 PRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGS 617
VC G+ +C+ EG P E C S G+ GS
Sbjct: 1099 QGVC--------GAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRT--SAGMF---PGS 1145
Query: 618 FLCDCDAGFEPSEDGTDCIDRRTGTCYRSLV-SGRCEPEXXXXXXXXXXXXXXXXXXXXX 676
+ P+ + RR T + V SGR E
Sbjct: 1146 QPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRE--------CYFDTAAPDACDNIL 1197
Query: 677 XGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXX 736
+VT +CCCT+G WGS C + PG+ + +L P
Sbjct: 1198 ARNVTWQECCCTVGEGWGSGCRIQQCPGT----ETAEYQSLCPHGRGYLAPSGD------ 1247
Query: 737 XXXXXLDVFADVDECAAI------PGLC---APGRFRCVCGPGYRPAGE--VCADVDECA 785
L + DVDEC G+C APG + C C GY + C D DECA
Sbjct: 1248 -----LSLRRDVDECQLFRDQVCKSGVCVNTAPG-YSCYCSNGYYYHTQRLECIDNDECA 1301
Query: 786 VRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANC 819
P C+ C NT GSY C C LD C
Sbjct: 1302 DEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC 1336
Score = 347 bits (853), Expect = 1e-94
Identities = 235/654 (35%), Positives = 303/654 (46%), Gaps = 75/654 (11%)
Query: 19 TKYLCCCS-VGHAWGAPCEACPPRGSPAHTALCGEKPGEY--INPVTNETKPIDECDIMP 75
TK +CCCS VG AWG C+ CPP GS +C PG + + + T+P+ +
Sbjct: 427 TKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRV 486
Query: 76 QLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC 135
L +P T T G+ +H E RP R + LP
Sbjct: 487 SLSQPRTLPATSRP-----SAGF---LPTHRLEPRPE---PRPDPRPGPE-FPLPSIPAW 534
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL--RENVCRDVD 193
P PS C+ + ++C G C + Y C C G+ L + C DVD
Sbjct: 535 TGPEIPESGPSSGMCQ-----RNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVD 589
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCRNGRCRNTV 252
EC R P C G CEN PG++ C C GF+AGP +C+DV+EC C GRC NT
Sbjct: 590 ECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTP 649
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
GSF C C GY G +C+DVDEC + P CGR +C N G + C C AG++ G
Sbjct: 650 GSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRG---ACKNLPGSFRCVCPAGFR--G 704
Query: 313 RRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKELCYDEWE 370
C D DEC + P C G C N G + C CPAG+R A C D +
Sbjct: 705 SACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCT 764
Query: 371 AGRCHRARPLQLARPECCCSEG---AAWGRYCE---------RCP------APDSAEFMR 412
GRC +C C G A G CE CP +P S + R
Sbjct: 765 YGRCENTE----GSFQCVCPMGFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQ-CR 819
Query: 413 ICQGG--MGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGL--SCV 467
C G + R T D+DEC C G C NT+GSFRC C GY AP G C
Sbjct: 820 ACPSGHHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY-RAPSGRPGPCA 877
Query: 468 DADECALDPRIC-GNGTCSNTRGGYECQCSPGFTQGP-DQTCVDVDECAEGRASCTFRCH 525
D +EC L+ C +G C NT G + C C+PG+ GP +C+DVDEC+E + C
Sbjct: 878 DVNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICT 936
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECVQE-PRVC-PHACENVVGSYIC--KCPEGYR 581
NT GSF C CP G+ D C D+DEC + P +C CEN GSY C C GY
Sbjct: 937 NTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYH 996
Query: 582 RTSAPQDSENACEDINECEEQ-EDLCSGGVCINTDGSFLCD--CDAGFEPSEDG 632
+ P E C+D++EC+E ++C C NT GS+ C CD G++P+ G
Sbjct: 997 --AGP---EGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG 1045
Score = 279 bits (685), Expect = 2e-74
Identities = 178/506 (35%), Positives = 225/506 (44%), Gaps = 38/506 (7%)
Query: 32 GAPCEACPPRGSPAHTA---LCGEKPGEYINPV--TNETKPIDECDIMPQLCKP-GTCHD 85
GAP C P G +T C PG Y P ++EC + C P G C +
Sbjct: 841 GAP--PCGPHGHCTNTEGSFRCSCAPG-YRAPSGRPGPCADVNEC-LEGDFCFPHGECLN 896
Query: 86 TPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTP 145
T F C C GY C DVDECS C+ C N G+FEC CPPG+R P
Sbjct: 897 TDGSFACTCAPGYRPGPRGASCLDVDECS-EEDLCQS-GICTNTDGSFECICPPGHRAGP 954
Query: 146 SLDECEDVDECGDQ--RICDHGDCRNTIGSYRC--ECKPGYTLR-ENVCRDVDECSRPRP 200
L C DVDEC ++ +C C N+ GSYRC +C PGY E C DVDEC P
Sbjct: 955 DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGP 1014
Query: 201 -VCRNGTCENLPGAYLCH--CDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRC 257
+C CEN PG+Y C CD G++ P C DV+ECR + C+N GSF+C
Sbjct: 1015 EICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQC 1074
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK----LVGR 313
C GY DGR+C DV+EC+ L CG C N G + C C + + GR
Sbjct: 1075 LCDQGYEGARDGRHCVDVNECETLQGVCGA---ALCENVEGSFLCVCPNSPEEFDPMTGR 1131
Query: 314 RCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEA-G 372
R P P R V + CY + A
Sbjct: 1132 CVPPRTSAGMFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPD 1191
Query: 373 RCHRARPLQLARPECCCSEGAAWGRYC--ERCPAPDSAEFMRICQGGMG--RPN----LT 424
C + ECCC+ G WG C ++CP ++AE+ +C G G P+ L
Sbjct: 1192 ACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLR 1251
Query: 425 QDLDECRV-RPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT 483
+D+DEC++ R VC G CVNT + C C +GY L C+D DECA + C G
Sbjct: 1252 RDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGR 1311
Query: 484 CSNTRGGYECQCSPGFT-QGPDQTCV 508
C NT G Y C C P G + CV
Sbjct: 1312 CVNTVGSYHCTCEPPLVLDGSQRRCV 1337
Score = 271 bits (664), Expect = 8e-72
Identities = 212/681 (31%), Positives = 280/681 (41%), Gaps = 61/681 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+DEC P C G C +T FQC C G++ + C DVDEC C G +CV
Sbjct: 753 VDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNAAGSECEDVDECE-NHLACPGQ-ECV 810
Query: 128 NLPGAFECR-CPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIGSYRCECKPGYTL 184
N PG+F+CR CP G+ L C DVDEC G HG C NT GS+RC C PGY
Sbjct: 811 NSPGSFQCRACPSGHHLHRG--RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA 868
Query: 185 ---RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGG 240
R C DV+EC +G C N G++ C C G++ GP C+DV+EC E
Sbjct: 869 PSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEED 928
Query: 241 MVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDEL-PHPCGRDGNPSCTNTNGG 299
+ C++G C NT GSF C C PG+ D +C DVDEC E P CG + C N+ G
Sbjct: 929 L-CQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCG---SQRCENSPGS 984
Query: 300 YEC--SCGAGWKLVGR-RCVDRDECKEL-PYVCAGGECRNFNGGYVCE--CPAGWRFDKT 353
Y C C G+ C D DEC+E P +C C N G Y C C G++
Sbjct: 985 YRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-PTP 1043
Query: 354 AAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMR- 412
C D + C + G H +C C +G R C + E ++
Sbjct: 1044 GGGCQDVDE--CRNRSFCG-AHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG 1100
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVC--VGGRCV---NTDGSFRCECPDGYVLAPDGLSCV 467
+C + L C P+ + GRCV + G F P +P +
Sbjct: 1101 VCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGMFPGSQPQAPA-SPVLPARP 1159
Query: 468 DADECALDPRICGNGTC-SNTRGGYECQCSPGFTQGPDQTCVDVDECA----EGRAS-CT 521
P G S R Y +P V EC EG S C
Sbjct: 1160 PPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCR 1219
Query: 522 FR-CHNT-AGSFRCTCPYG---YAVAADGVHCRDIDEC-VQEPRVCPHA-CENVVGSYIC 574
+ C T ++ CP+G A + D RD+DEC + +VC C N Y C
Sbjct: 1220 IQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSC 1279
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTD 634
C GY + + C D +EC ++E C GG C+NT GS+ C C+
Sbjct: 1280 YCSNGYYYHTQRLE----CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRR 1335
Query: 635 CIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWG 694
C+ + + +L G C E T +CCC G AWG
Sbjct: 1336 CVSNESQSLDDNL--GVCWQEVGADLVCSHPRLDR---------QATYTECCCLYGEAWG 1384
Query: 695 SECELCPAPGSPARLDLCTAV 715
+C LCPA S LC +
Sbjct: 1385 MDCALCPAQDSDDFEALCNVL 1405
Score = 269 bits (659), Expect = 3e-71
Identities = 177/498 (35%), Positives = 222/498 (44%), Gaps = 44/498 (8%)
Query: 29 HAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPT 88
H PC+ +P + LC G P + +DEC P LC G C + P
Sbjct: 634 HRVPPPCDLGRCENTPG-SFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPG 692
Query: 89 GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD 148
F+C C G+ DVDEC+ PPC G +C N G+F C CP G+R
Sbjct: 693 SFRCVCPAGFRGSACEE---DVDECAQEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGA 748
Query: 149 ECEDVDECG-DQRICDHGDCRNTIGSYRCECKPGY--TLRENVCRDVDECSRPRPVCRNG 205
C+DVDEC C +G C NT GS++C C G+ + C DVDEC C
Sbjct: 749 PCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNAAGSECEDVDECEN-HLACPGQ 807
Query: 206 TCENLPGAYLCH-CDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRCECAPGY 263
C N PG++ C C G C DV+EC G C +G C NT GSFRC CAPGY
Sbjct: 808 ECVNSPGSFQCRACPSGHHLHRGR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY 866
Query: 264 TLTADGRN--CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRD 319
+ GR C DV+EC E C G C NT+G + C+C G++ G C+D D
Sbjct: 867 RAPS-GRPGPCADVNECLEGDF-CFPHGE--CLNTDGSFACTCAPGYRPGPRGASCLDVD 922
Query: 320 ECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-----ER------KELCYDE 368
EC E +C G C N +G + C CP G R A C+D ER + C +
Sbjct: 923 ECSEED-LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENS 981
Query: 369 WEAGRCHR-ARPLQLARPECCCSEGAAWGRY------CERCP-APDSAEFMRICQGGMGR 420
+ RC R P A PE C + Y +RC P S C G +
Sbjct: 982 PGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGY-Q 1040
Query: 421 PNL---TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPR 477
P QD+DECR R C N GSF+C C GY A DG CVD +EC
Sbjct: 1041 PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG 1100
Query: 478 ICGNGTCSNTRGGYECQC 495
+CG C N G + C C
Sbjct: 1101 VCGAALCENVEGSFLCVC 1118
Score = 203 bits (496), Expect = 2e-51
Identities = 97/230 (42%), Positives = 120/230 (52%), Gaps = 15/230 (6%)
Query: 430 CRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRG 489
C+ P VC GRC++ + C C G+ L+P G C+D DEC P C G C N+ G
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 608
Query: 490 GYECQCSPGFTQGPDQT-CVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYAVAADGVH 547
+ C C PGF GP C+DVDEC C RC NT GSF C CP GY A G
Sbjct: 609 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 668
Query: 548 CRDIDECVQEPRVCPH-ACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLC 606
C+D+DEC Q P +C AC+N+ GS+ C CP G+R ++ ED++EC ++ C
Sbjct: 669 CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACE-------EDVDECAQEPPPC 721
Query: 607 SGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS---LVSGRCE 653
G C NT GSF C C AGF G C D C RS GRCE
Sbjct: 722 GPGRCDNTAGSFHCACPAGFRSRGPGAPCQD--VDECARSPPPCTYGRCE 769
Score = 124 bits (299), Expect = 1e-27
Identities = 61/123 (49%), Positives = 72/123 (58%), Gaps = 13/123 (10%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ-LCH 796
DVDEC +P CAPGR FRCVCGPG+R P C DVDEC PPPCD C
Sbjct: 587 DVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCE 646
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEKRG 855
NT GS+ C+C GY+ GA+C+DVDEC + C + C N GS+ C C G+ RG
Sbjct: 647 NTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGF--RG 704
Query: 856 DAC 858
AC
Sbjct: 705 SAC 707
Score = 107 bits (258), Expect = 1e-22
Identities = 53/123 (43%), Positives = 66/123 (53%), Gaps = 11/123 (8%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYRPAGE--VCADVDECAVRPPPCDQ-LCH 796
DVDECA P C PGR F C C G+R G C DVDECA PPPC C
Sbjct: 710 DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCE 769
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC-SCEDGYEKRG 855
NT+GS+ C+C G++ + G+ C DVDECE Q C N+ GS++C +C G+
Sbjct: 770 NTEGSFQCVCPMGFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQCRACPSGHHLHR 829
Query: 856 DAC 858
C
Sbjct: 830 GRC 832
Score = 97.5 bits (232), Expect = 2e-19
Identities = 54/123 (43%), Positives = 66/123 (53%), Gaps = 14/123 (11%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYR-PAGEV--CADVDECAVRPPPC--DQ 793
DVDEC++ C P G FRC C PGYR P+G CADV+EC + C
Sbjct: 834 DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNEC-LEGDFCFPHG 892
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C NTDGS+ C C GY GA+C DVDEC + IC+NT+GS+EC C G+
Sbjct: 893 ECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRA 952
Query: 854 RGD 856
D
Sbjct: 953 GPD 955
Score = 97.5 bits (232), Expect = 2e-19
Identities = 54/119 (45%), Positives = 64/119 (53%), Gaps = 13/119 (10%)
Query: 746 ADVDECA----AIP-GLC--APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCH 796
ADV+EC P G C G F C C PGYRP G C DVDEC+ +C
Sbjct: 877 ADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICT 936
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDEC-ERDTHTC-QQICSNTEGSYEC--SCEDGY 851
NTDGS++C+C G+ D A+C DVDEC ER C Q C N+ GSY C C+ GY
Sbjct: 937 NTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGY 995
Score = 95.5 bits (227), Expect = 7e-19
Identities = 47/133 (35%), Positives = 68/133 (51%), Gaps = 7/133 (5%)
Query: 23 CCCSVGHAWGAPC--EACPPRGSPAHTALCGEKPGEYINPVTNET--KPIDECDIM-PQL 77
CCC+VG WG+ C + CP + + +LC G Y+ P + + + +DEC + Q+
Sbjct: 1206 CCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRG-YLAPSGDLSLRRDVDECQLFRDQV 1264
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRC 137
CK G C +T G+ C C +GY + C D DEC+ P C G +CVN G++ C C
Sbjct: 1265 CKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEG-GRCVNTVGSYHCTC 1323
Query: 138 PPGYRLTPSLDEC 150
P L S C
Sbjct: 1324 EPPLVLDGSQRRC 1336
Score = 93.1 bits (221), Expect = 4e-18
Identities = 47/113 (41%), Positives = 56/113 (49%), Gaps = 11/113 (9%)
Query: 751 CAAIPGLCAPGR-------FRCVCGPGYR--PAGEVCADVDECAVRPPPC-DQLCHNTDG 800
C P +C PGR + C C G+R P G C DVDEC PPPC C N+ G
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 608
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYE 852
S+ C+C G+ A C DVDEC R C C NT GS+ C C GY+
Sbjct: 609 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQ 661
Score = 92.7 bits (220), Expect = 5e-18
Identities = 65/198 (32%), Positives = 86/198 (43%), Gaps = 23/198 (11%)
Query: 2 EWNEEDQSCAGAVGVPQTKYLCCCSVGHAWG---APC---EACPPRG-SPAHTALCGEKP 54
E +EED +G + C C GH G A C + C RG + + C P
Sbjct: 923 ECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSP 982
Query: 55 GEY-----INP-----VTNETKPIDEC-DIMPQLCKPGTCHDTPTGFQC--GCDHGYEHD 101
G Y +P +DEC + P++C C +TP ++C CD GY+
Sbjct: 983 GSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-P 1041
Query: 102 NTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QR 160
C+DVDEC R C A C NLPG+F+C C GY C DV+EC Q
Sbjct: 1042 TPGGGCQDVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG 1100
Query: 161 ICDHGDCRNTIGSYRCEC 178
+C C N GS+ C C
Sbjct: 1101 VCGAALCENVEGSFLCVC 1118
Score = 91.1 bits (216), Expect = 2e-17
Identities = 51/120 (42%), Positives = 62/120 (51%), Gaps = 13/120 (10%)
Query: 747 DVDECAAI-PGLCA-------PGRFRCV--CGPGYRPA-GEVCADVDECAVRP-PPCDQL 794
DVDEC P +C PG +RC C PGY+P G C DVDEC R +
Sbjct: 1005 DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAV 1064
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEK 853
C N GS+ CLC GYE DG +C DV+ECE C +C N EGS+ C C + E+
Sbjct: 1065 CQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEE 1124
Score = 89.8 bits (213), Expect = 4e-17
Identities = 57/131 (43%), Positives = 66/131 (50%), Gaps = 19/131 (14%)
Query: 747 DVDECAAI-PGLC-------APGRFRCV--CGPGYRPAGE-VCADVDECAVRPPP-CD-Q 793
DVDEC P LC +PG +RCV C PGY E C DVDEC P C Q
Sbjct: 961 DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQ 1020
Query: 794 LCHNTDGSYDCL--CRTGYELDEDGANCRDVDECE-RDTHTCQQICSNTEGSYECSCEDG 850
C NT GSY C C GY+ G C+DVDEC R +C N GS++C C+ G
Sbjct: 1021 RCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQG 1079
Query: 851 YE--KRGDACV 859
YE + G CV
Sbjct: 1080 YEGARDGRHCV 1090
Score = 87.8 bits (208), Expect = 1e-16
Identities = 55/129 (42%), Positives = 67/129 (51%), Gaps = 18/129 (13%)
Query: 747 DVDECA----AIPGLCA--PGRFRCVCGPGYRPAGEV--CADVDECAVRPPP-C-DQLCH 796
DVDEC+ G+C G F C+C PG+R ++ C DVDEC R P C Q C
Sbjct: 920 DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCE 979
Query: 797 NTDGSYDCL--CRTGYELDEDGANCRDVDEC-ERDTHTC-QQICSNTEGSYEC--SCEDG 850
N+ GSY C+ C GY +G C DVDEC E C Q C NT GSY C +C+ G
Sbjct: 980 NSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPG 1038
Query: 851 YEKR-GDAC 858
Y+ G C
Sbjct: 1039 YQPTPGGGC 1047
Score = 85.0 bits (201), Expect = 1e-15
Identities = 47/130 (36%), Positives = 57/130 (43%), Gaps = 7/130 (5%)
Query: 304 CGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVC-----V 358
C G++ V C D DEC C GEC N GGY C CP G+ D + + C +
Sbjct: 344 CPTGFERVNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 402
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSE-GAAWGRYCERCPAPDSAEFMRICQGG 417
E K C+ G C + + CCCS G AWGR C+ CP S F IC G
Sbjct: 403 SEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAG 462
Query: 418 MGRPNLTQDL 427
G DL
Sbjct: 463 PGYHYSASDL 472
Score = 83.8 bits (198), Expect = 2e-15
Identities = 52/126 (41%), Positives = 64/126 (50%), Gaps = 13/126 (10%)
Query: 747 DVDECA---AIPGL-C--APGRFRC-VCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHN 797
DVDEC A PG C +PG F+C C G+ C DVDEC+ PPC C N
Sbjct: 794 DVDECENHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTN 853
Query: 798 TDGSYDCLCRTGYELDEDGAN-CRDVDEC-ERDTHTCQQICSNTEGSYECSCEDGYE--K 853
T+GS+ C C GY C DV+EC E D C NT+GS+ C+C GY
Sbjct: 854 TEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGP 913
Query: 854 RGDACV 859
RG +C+
Sbjct: 914 RGASCL 919
Score = 72.1 bits (169), Expect = 8e-12
Identities = 32/75 (42%), Positives = 40/75 (53%), Gaps = 4/75 (5%)
Query: 202 CRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREG---GMVCRNGRCRNTVGSFRC 257
C NG C +P + C C DG++ CVD+NEC E +C N RC NT GSFRC
Sbjct: 1543 CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC 1602
Query: 258 ECAPGYTLTADGRNC 272
C PG+ T +C
Sbjct: 1603 ICRPGFAPTHQPHHC 1617
Score = 70.9 bits (166), Expect = 2e-11
Identities = 35/88 (39%), Positives = 44/88 (50%), Gaps = 6/88 (6%)
Query: 416 GGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC--- 472
G + P + +EC + D C GRCV F C C DGY L ++CVD +EC
Sbjct: 1523 GSLAEPYEELEAEECGIL-DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEA 1581
Query: 473 -ALDPRICGNGTCSNTRGGYECQCSPGF 499
A P +C N C NT G + C C PGF
Sbjct: 1582 EAASP-LCVNARCLNTDGSFRCICRPGF 1608
Score = 65.7 bits (153), Expect = 7e-10
Identities = 44/145 (30%), Positives = 60/145 (41%), Gaps = 33/145 (22%)
Query: 576 CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
CP G+ R + +CED++EC C G C NT G + C C GF + C
Sbjct: 344 CPTGFERVNG------SCEDVDECATG-GRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 396
Query: 636 IDRRT-----GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCT-L 689
I + G C+R L G C ++TK CCC+ +
Sbjct: 397 ISQHVISEAKGPCFRVLRDGGC--------------------SLPILRNITKQICCCSRV 436
Query: 690 GAAWGSECELCPAPGSPARLDLCTA 714
G AWG C+LCP GS ++C A
Sbjct: 437 GKAWGRGCQLCPPFGSEGFREICPA 461
Score = 63.3 bits (147), Expect = 4e-09
Identities = 36/90 (40%), Positives = 44/90 (48%), Gaps = 6/90 (6%)
Query: 765 CVCGPGY-RPAGEVCA--DVDECAV-RPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANC 819
C G GY P+G++ DVDEC + R C +C NT Y C C GY C
Sbjct: 1235 CPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLEC 1294
Query: 820 RDVDECERDTHTCQ-QICSNTEGSYECSCE 848
D DEC + C+ C NT GSY C+CE
Sbjct: 1295 IDNDECADEEPACEGGRCVNTVGSYHCTCE 1324
Score = 62.9 bits (146), Expect = 5e-09
Identities = 32/78 (41%), Positives = 39/78 (50%), Gaps = 7/78 (8%)
Query: 565 CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQE---DLCSGGVCINTDGSFLCD 621
C V + C+C +GYR + AC DINEC+E E LC C+NTDGSF C
Sbjct: 1548 CVRVPEGFTCRCFDGYRLDM----TRMACVDINECDEAEAASPLCVNARCLNTDGSFRCI 1603
Query: 622 CDAGFEPSEDGTDCIDRR 639
C GF P+ C R
Sbjct: 1604 CRPGFAPTHQPHHCAPAR 1621
Score = 62.1 bits (144), Expect = 8e-09
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 6/87 (6%)
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCTF--- 522
++A+EC + C NG C G+ C+C G+ + CVD++EC E A+
Sbjct: 1532 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1590
Query: 523 -RCHNTAGSFRCTCPYGYAVAADGVHC 548
RC NT GSFRC C G+A HC
Sbjct: 1591 ARCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 62.1 bits (144), Expect = 8e-09
Identities = 26/62 (41%), Positives = 37/62 (59%), Gaps = 4/62 (6%)
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQR----ICDHGDCRNTIGSYRCECKP 180
+CV +P F CRC GYRL + C D++EC + +C + C NT GS+RC C+P
Sbjct: 1547 RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRP 1606
Query: 181 GY 182
G+
Sbjct: 1607 GF 1608
Score = 61.3 bits (142), Expect = 1e-08
Identities = 31/84 (36%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDEC--SWGRPPCRGMAQC 126
+EC I+ C G C P GF C C GY D T C D++EC + P A+C
Sbjct: 1535 EECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARC 1593
Query: 127 VNLPGAFECRCPPGYRLTPSLDEC 150
+N G+F C C PG+ T C
Sbjct: 1594 LNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 60.5 bits (140), Expect = 2e-08
Identities = 36/110 (32%), Positives = 50/110 (45%), Gaps = 8/110 (7%)
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWGRY-CERCPAP-DSAEFMRI----CQGGM 418
C+ E G C P + CC G AWG + C+ C ++E + C G
Sbjct: 289 CFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGF 348
Query: 419 GRPNLT-QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
R N + +D+DEC C G C NT G + C CPDG++L SC+
Sbjct: 349 ERVNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCI 397
Score = 59.3 bits (137), Expect = 6e-08
Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Query: 219 DDGFKAGPNNDCVDVNECREGGMV--CRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVD 276
+ G AG + + E E G++ C NGRC F C C GY L C D++
Sbjct: 1517 EGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDIN 1576
Query: 277 ECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
ECDE N C NT+G + C C G+
Sbjct: 1577 ECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1608
Score = 56.4 bits (130), Expect = 4e-07
Identities = 36/104 (34%), Positives = 44/104 (42%), Gaps = 9/104 (8%)
Query: 218 CDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE 277
C GF+ N C DV+EC GG C++G C NT G + C C G+ L + +C
Sbjct: 344 CPTGFER-VNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHV 401
Query: 278 CDELPHPCG---RDGN---PSCTNTNGGYECSCGAGWKLVGRRC 315
E PC RDG P N C C K GR C
Sbjct: 402 ISEAKGPCFRVLRDGGCSLPILRNITKQI-CCCSRVGKAWGRGC 444
Score = 56.0 bits (129), Expect = 5e-07
Identities = 33/85 (38%), Positives = 42/85 (49%), Gaps = 8/85 (9%)
Query: 453 CPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGF-TQGPDQTCVDVD 511
CP G+ +G SC D DECA R C +G C+NTRGGY C C GF +C+
Sbjct: 344 CPTGFERV-NG-SCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQH 400
Query: 512 ECAEGRASCTFRCHNTAGSFRCTCP 536
+E + C FR G C+ P
Sbjct: 401 VISEAKGPC-FRVLRDGG---CSLP 421
Score = 53.2 bits (122), Expect = 4e-06
Identities = 22/48 (45%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
CP G+ CEDVDEC C HG+C NT G Y C C G+ L
Sbjct: 344 CPTGFERVNG--SCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLL 389
Score = 51.6 bits (118), Expect = 1e-05
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 5/76 (6%)
Query: 152 DVDECGDQRICDHGDCRNTIGSYRCECKPGYTL--RENVCRDVDECSRPR---PVCRNGT 206
+ +ECG C +G C + C C GY L C D++EC P+C N
Sbjct: 1533 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1592
Query: 207 CENLPGAYLCHCDDGF 222
C N G++ C C GF
Sbjct: 1593 CLNTDGSFRCICRPGF 1608
Score = 50.4 bits (115), Expect = 3e-05
Identities = 33/114 (28%), Positives = 50/114 (43%), Gaps = 5/114 (4%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGA-PCEACPPR--GSPAHTALCGEKPGEYINPVTNETK 66
CA + +T+ +CC G AWG C+ C R S +A G P + V +
Sbjct: 298 CASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGF-ERVNGSCE 356
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+DEC + C+ G C +T G+ C C G+ D++ C S + PC
Sbjct: 357 DVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPC 409
Score = 47.6 bits (108), Expect = 2e-04
Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 14/86 (16%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYR--PAGEVCADVDEC----AVRPPPCDQ 793
+ +EC + G C GR F C C GYR C D++EC A P +
Sbjct: 1533 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANC 819
C NTDGS+ C+CR G+ +C
Sbjct: 1592 RCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 4/76 (5%)
Query: 780 DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC---ERDTHTCQQI- 835
+ +EC + + C + C C GY LD C D++EC E + C
Sbjct: 1533 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1592
Query: 836 CSNTEGSYECSCEDGY 851
C NT+GS+ C C G+
Sbjct: 1593 CLNTDGSFRCICRPGF 1608
Score = 45.6 bits (103), Expect = 8e-04
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 6/76 (7%)
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNEC 236
C G+ C DVDEC+ C++G C N G Y C C DGF + C+ +
Sbjct: 344 CPTGFERVNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 402
Query: 237 REGGMVC----RNGRC 248
E C R+G C
Sbjct: 403 SEAKGPCFRVLRDGGC 418
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/57 (40%), Positives = 28/57 (49%), Gaps = 4/57 (7%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDEC 150
C G+E N S C DVDEC+ G G +C N G + C CP G+ L S C
Sbjct: 344 CPTGFERVNGS--CEDVDECATGGRCQHG--ECANTRGGYTCVCPDGFLLDSSRSSC 396
Score = 45.2 bits (102), Expect = 0.001
Identities = 20/53 (37%), Positives = 25/53 (47%)
Query: 767 CGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
C G+ C DVDECA C NT G Y C+C G+ LD ++C
Sbjct: 344 CPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 396
Score = 45.2 bits (102), Expect = 0.001
Identities = 29/91 (31%), Positives = 37/91 (40%), Gaps = 3/91 (3%)
Query: 381 QLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ--DLDECRVRPDVCV 438
+L EC +G GR C R P + + M R + DE +CV
Sbjct: 1531 ELEAEECGILDGCTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1589
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
RC+NTDGSFRC C G+ C A
Sbjct: 1590 NARCLNTDGSFRCICRPGFAPTHQPHHCAPA 1620
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/105 (34%), Positives = 50/105 (47%), Gaps = 17/105 (16%)
Query: 750 ECAA-IPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTD--GSYDCLC 806
ECA+ +PGL R + VC G AG + V +C + C + N++ + D C
Sbjct: 297 ECASPLPGL----RTQEVCCRG---AG-LAWGVHDCQL----CSERLGNSERVSAPDGPC 344
Query: 807 RTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
TG+E +C DVDEC C+NT G Y C C DG+
Sbjct: 345 PTGFE--RVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGF 387
Score = 44.0 bits (99), Expect = 0.002
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Query: 495 CSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC 548
C GF + + +C DVDECA G C NT G + C CP G+ + + C
Sbjct: 344 CPTGFER-VNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 396
Score = 43.2 bits (97), Expect = 0.004
Identities = 33/105 (31%), Positives = 40/105 (38%), Gaps = 6/105 (5%)
Query: 480 GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGY 539
G G C G EC SP + C A G C S R + P G
Sbjct: 285 GFGYCFRELRGGEC-ASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGP 343
Query: 540 AVAA-DGVH--CRDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
+ V+ C D+DEC R C H C N G Y C CP+G+
Sbjct: 344 CPTGFERVNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGF 387
Score = 42.7 bits (96), Expect = 0.005
Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 10/102 (9%)
Query: 489 GGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC 548
G Y + + + + C +D C GR C F C C GY + + C
Sbjct: 1519 GSYAGSLAEPYEELEAEECGILDGCTNGR------CVRVPEGFTCRCFDGYRLDMTRMAC 1572
Query: 549 RDIDECVQEPR---VCPHA-CENVVGSYICKCPEGYRRTSAP 586
DI+EC + +C +A C N GS+ C C G+ T P
Sbjct: 1573 VDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQP 1614
Score = 40.3 bits (90), Expect = 0.028
Identities = 17/39 (43%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 23 CCCSVGHAWGAPCEACPPRGSPAHTALCGE-KPGEYINP 60
CCC G AWG C CP + S ALC +P Y P
Sbjct: 1375 CCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPP 1413
Score = 39.1 bits (87), Expect = 0.066
Identities = 29/82 (35%), Positives = 35/82 (42%), Gaps = 7/82 (8%)
Query: 316 VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGR-- 373
++ +EC L C G C G+ C C G+R D T CVD + C DE EA
Sbjct: 1532 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINE--C-DEAEAASPL 1587
Query: 374 CHRARPLQL-ARPECCCSEGAA 394
C AR L C C G A
Sbjct: 1588 CVNARCLNTDGSFRCICRPGFA 1609
Score = 37.5 bits (83), Expect = 0.20
Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 6/65 (9%)
Query: 793 QLCHNTD-GSYDCLCR--TGYELDEDGANCR-DVDECE--RDTHTCQQICSNTEGSYECS 846
Q C T+ Y LC GY + R DVDEC+ RD +C NT Y C
Sbjct: 1221 QQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY 1280
Query: 847 CEDGY 851
C +GY
Sbjct: 1281 CSNGY 1285
>AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming growth
factor-beta binding protein 4S protein.
Length = 1557
Score = 412 bits (1015), Expect = e-114
Identities = 230/585 (39%), Positives = 292/585 (49%), Gaps = 60/585 (10%)
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLP 130
C PQ+C PG C P+G+ C CD G+ C DVDEC PPC +C N P
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSP 540
Query: 131 GAFECRCPPGYRLTPSLDECEDVDECGDQRI---CDHGDCRNTIGSYRCECKPGYTLREN 187
G+F C C PG+R P EC DVDEC R+ CD G C NT GS+ C C GY +
Sbjct: 541 GSFRCVCGPGFRAGPRAAECLDVDEC--HRVPPPCDLGRCENTPGSFLCVCPAGYQAAPH 598
Query: 188 --VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN 245
C+DVDEC++ +C G C+NLPG++ C C GF+ + DV+EC + C
Sbjct: 599 GASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEE--DVDECAQEPPPCGP 656
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
GRC NT GSF C C G+ G C+DVDEC P PC C NT G ++C C
Sbjct: 657 GRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG---RCENTEGSFQCVCP 713
Query: 306 AGWK--LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCE-CPAGWRFDKTAAVCVDERK 362
G++ G C D DEC E C G EC N G + C CP+G + VDE
Sbjct: 714 MGFQPNAAGSECEDVDEC-ENHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDE-- 770
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPN 422
C P C +EG+ C P + GRP
Sbjct: 771 -----------CSSGAPPCGPHGHCTNTEGSF---RCSCAPG---------YRAPSGRPG 807
Query: 423 LTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGN 481
D++EC + D C G C+NTDGSF C C GY P G SC+D DEC+ + +C +
Sbjct: 808 PCADVNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS-EEDLCQS 865
Query: 482 GTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAE-GRASC-TFRCHNTAGSFRCT--CP 536
G C+NT G +EC C PG GPD +C+DVDEC E G A C + RC N+ GS+RC C
Sbjct: 866 GICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCD 925
Query: 537 YGYAVAADGVHCRDIDECVQ-EPRVC-PHACENVVGSYIC--KCPEGYRRTSAPQDSENA 592
GY +G C D+DEC + P +C CEN GSY C C GY+ T
Sbjct: 926 PGYHAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPG-----GG 979
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C+D++EC + + VC N GSF C CD G+E + DG C+D
Sbjct: 980 CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD 1024
Score = 399 bits (983), Expect = e-110
Identities = 228/607 (37%), Positives = 296/607 (48%), Gaps = 55/607 (9%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C G ++P +DEC +P C PG C ++P F+C C G+ + C D
Sbjct: 503 CACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLD 562
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQ-RICDHGDCR 168
VDEC PPC + +C N PG+F C CP GY+ P C+DVDEC +C G C+
Sbjct: 563 VDECHRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACK 621
Query: 169 NTIGSYRCECKPGYTLRENVC-RDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA-GP 226
N GS+RC C G+ R + C DVDEC++ P C G C+N G++ C C GF++ GP
Sbjct: 622 NLPGSFRCVCPAGF--RGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGP 679
Query: 227 NNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C DV+EC C GRC NT GSF+C C G+ A G C DVDEC+ G
Sbjct: 680 GAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNAAGSECEDVDECENHLACPG 739
Query: 287 RDGNPSCTNTNGGYEC-SCGAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCEC 344
++ C N+ G ++C +C +G L RC D DEC C G C N G + C C
Sbjct: 740 QE----CVNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSC 795
Query: 345 PAGWRFDK-TAAVCVDERKELCYDE-WEAGRCHRARPLQLARPECCCSEGAAWGRYCERC 402
G+R C D + L D + G C C C+ G
Sbjct: 796 APGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTD----GSFACTCAPGYR-------- 843
Query: 403 PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPD 462
P P A + + DEC D+C G C NTDGSF C CP G+ PD
Sbjct: 844 PGPRGASCLDV--------------DECS-EEDLCQSGICTNTDGSFECICPPGHRAGPD 888
Query: 463 GLSCVDADEC-ALDPRICGNGTCSNTRGGYEC--QCSPGFTQGPDQTCVDVDECAE-GRA 518
SC+D DEC P +CG+ C N+ G Y C C PG+ GP+ TC DVDEC E G
Sbjct: 889 LASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPE 948
Query: 519 SC-TFRCHNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYIC 574
C RC NT GS+RCT C GY G C+D+DEC HA C+N+ GS+ C
Sbjct: 949 ICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNRSFCGAHAVCQNLPGSFQC 1007
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTD 634
C +GY +D + C D+NECE + +C +C N +GSFLC C E + T
Sbjct: 1008 LCDQGY---EGARDGRH-CVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTG 1063
Query: 635 -CIDRRT 640
C+ RT
Sbjct: 1064 RCVPPRT 1070
Score = 380 bits (936), Expect = e-105
Identities = 279/815 (34%), Positives = 349/815 (42%), Gaps = 104/815 (12%)
Query: 34 PCEACPPRGSP-AHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQC 92
PC SP + +CG PG P E +DEC +P C G C +TP F C
Sbjct: 530 PCAPGRCENSPGSFRCVCG--PGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLC 587
Query: 93 GCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECED 152
C GY+ C+DVDEC+ C G C NLPG+F C CP G+R S E ED
Sbjct: 588 VCPAGYQAAPHGASCQDVDECTQSPGLC-GRGACKNLPGSFRCVCPAGFR--GSACE-ED 643
Query: 153 VDECGDQRI-CDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCEN 209
VDEC + C G C NT GS+ C C G+ R C+DVDEC+R P C G CEN
Sbjct: 644 VDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCEN 703
Query: 210 LPGAYLCHCDDGFKAGP-NNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTAD 268
G++ C C GF+ ++C DV+EC E + C C N+ GSF+C P
Sbjct: 704 TEGSFQCVCPMGFQPNAAGSECEDVDEC-ENHLACPGQECVNSPGSFQCRACPSGHHLHR 762
Query: 269 GRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR---CVDRDECKELP 325
GR C DVDEC PCG G+ CTNT G + CSC G++ R C D +EC E
Sbjct: 763 GR-CTDVDECSSGAPPCGPHGH--CTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGD 819
Query: 326 YVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARP 385
+ GEC N +G + C C G+R A C+D + D ++G C
Sbjct: 820 FCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTD----GSF 875
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVR-PDVCVGGRCVN 444
EC C G G PD A + D+DECR R P +C RC N
Sbjct: 876 ECICPPGHRAG--------PDLASCL--------------DVDECRERGPALCGSQRCEN 913
Query: 445 TDGSFRC--ECPDGYVLAPDGLSCVDADECA-LDPRICGNGTCSNTRGGYECQ--CSPGF 499
+ GS+RC +C GY P+G +C D DEC P ICG C NT G Y C C PG+
Sbjct: 914 SPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGY 972
Query: 500 TQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQE 557
P C DVDEC R+ C C N GSF+C C GY A DG HC D++EC
Sbjct: 973 QPTPGGGCQDVDEC-RNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETL 1031
Query: 558 PRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGS 617
VC G+ +C+ EG P E C S G+ GS
Sbjct: 1032 QGVC--------GAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRT--SAGMF---PGS 1078
Query: 618 FLCDCDAGFEPSEDGTDCIDRRTGTCYRSLV-SGRCEPEXXXXXXXXXXXXXXXXXXXXX 676
+ P+ + RR T + V SGR E
Sbjct: 1079 QPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRE--------CYFDTAAPDACDNIL 1130
Query: 677 XGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXX 736
+VT +CCCT+G WGS C + PG+ + +L P
Sbjct: 1131 ARNVTWQECCCTVGEGWGSGCRIQQCPGT----ETAEYQSLCPHGRGYLAPSGD------ 1180
Query: 737 XXXXXLDVFADVDECAAI------PGLC---APGRFRCVCGPGYRPAGE--VCADVDECA 785
L + DVDEC G+C APG + C C GY + C D DECA
Sbjct: 1181 -----LSLRRDVDECQLFRDQVCKSGVCVNTAPG-YSCYCSNGYYYHTQRLECIDNDECA 1234
Query: 786 VRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANC 819
P C+ C NT GSY C C LD C
Sbjct: 1235 DEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC 1269
Score = 347 bits (853), Expect = 1e-94
Identities = 235/654 (35%), Positives = 303/654 (46%), Gaps = 75/654 (11%)
Query: 19 TKYLCCCS-VGHAWGAPCEACPPRGSPAHTALCGEKPGEY--INPVTNETKPIDECDIMP 75
TK +CCCS VG AWG C+ CPP GS +C PG + + + T+P+ +
Sbjct: 360 TKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRV 419
Query: 76 QLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC 135
L +P T T G+ +H E RP R + LP
Sbjct: 420 SLSQPRTLPATSRP-----SAGF---LPTHRLEPRPE---PRPDPRPGPE-FPLPSIPAW 467
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL--RENVCRDVD 193
P PS C+ + ++C G C + Y C C G+ L + C DVD
Sbjct: 468 TGPEIPESGPSSGMCQ-----RNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVD 522
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCRNGRCRNTV 252
EC R P C G CEN PG++ C C GF+AGP +C+DV+EC C GRC NT
Sbjct: 523 ECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTP 582
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
GSF C C GY G +C+DVDEC + P CGR +C N G + C C AG++ G
Sbjct: 583 GSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRG---ACKNLPGSFRCVCPAGFR--G 637
Query: 313 RRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKELCYDEWE 370
C D DEC + P C G C N G + C CPAG+R A C D +
Sbjct: 638 SACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCT 697
Query: 371 AGRCHRARPLQLARPECCCSEG---AAWGRYCE---------RCP------APDSAEFMR 412
GRC +C C G A G CE CP +P S + R
Sbjct: 698 YGRCENTE----GSFQCVCPMGFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQ-CR 752
Query: 413 ICQGG--MGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGL--SCV 467
C G + R T D+DEC C G C NT+GSFRC C GY AP G C
Sbjct: 753 ACPSGHHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY-RAPSGRPGPCA 810
Query: 468 DADECALDPRIC-GNGTCSNTRGGYECQCSPGFTQGP-DQTCVDVDECAEGRASCTFRCH 525
D +EC L+ C +G C NT G + C C+PG+ GP +C+DVDEC+E + C
Sbjct: 811 DVNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICT 869
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECVQE-PRVC-PHACENVVGSYIC--KCPEGYR 581
NT GSF C CP G+ D C D+DEC + P +C CEN GSY C C GY
Sbjct: 870 NTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYH 929
Query: 582 RTSAPQDSENACEDINECEEQ-EDLCSGGVCINTDGSFLCD--CDAGFEPSEDG 632
+ P E C+D++EC+E ++C C NT GS+ C CD G++P+ G
Sbjct: 930 --AGP---EGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG 978
Score = 279 bits (685), Expect = 2e-74
Identities = 178/506 (35%), Positives = 225/506 (44%), Gaps = 38/506 (7%)
Query: 32 GAPCEACPPRGSPAHTA---LCGEKPGEYINPV--TNETKPIDECDIMPQLCKP-GTCHD 85
GAP C P G +T C PG Y P ++EC + C P G C +
Sbjct: 774 GAP--PCGPHGHCTNTEGSFRCSCAPG-YRAPSGRPGPCADVNEC-LEGDFCFPHGECLN 829
Query: 86 TPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTP 145
T F C C GY C DVDECS C+ C N G+FEC CPPG+R P
Sbjct: 830 TDGSFACTCAPGYRPGPRGASCLDVDECS-EEDLCQS-GICTNTDGSFECICPPGHRAGP 887
Query: 146 SLDECEDVDECGDQ--RICDHGDCRNTIGSYRC--ECKPGYTLR-ENVCRDVDECSRPRP 200
L C DVDEC ++ +C C N+ GSYRC +C PGY E C DVDEC P
Sbjct: 888 DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGP 947
Query: 201 -VCRNGTCENLPGAYLCH--CDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRC 257
+C CEN PG+Y C CD G++ P C DV+ECR + C+N GSF+C
Sbjct: 948 EICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQC 1007
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK----LVGR 313
C GY DGR+C DV+EC+ L CG C N G + C C + + GR
Sbjct: 1008 LCDQGYEGARDGRHCVDVNECETLQGVCGA---ALCENVEGSFLCVCPNSPEEFDPMTGR 1064
Query: 314 RCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEA-G 372
R P P R V + CY + A
Sbjct: 1065 CVPPRTSAGMFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPD 1124
Query: 373 RCHRARPLQLARPECCCSEGAAWGRYC--ERCPAPDSAEFMRICQGGMG--RPN----LT 424
C + ECCC+ G WG C ++CP ++AE+ +C G G P+ L
Sbjct: 1125 ACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLR 1184
Query: 425 QDLDECRV-RPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT 483
+D+DEC++ R VC G CVNT + C C +GY L C+D DECA + C G
Sbjct: 1185 RDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGR 1244
Query: 484 CSNTRGGYECQCSPGFT-QGPDQTCV 508
C NT G Y C C P G + CV
Sbjct: 1245 CVNTVGSYHCTCEPPLVLDGSQRRCV 1270
Score = 271 bits (664), Expect = 8e-72
Identities = 212/681 (31%), Positives = 280/681 (41%), Gaps = 61/681 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+DEC P C G C +T FQC C G++ + C DVDEC C G +CV
Sbjct: 686 VDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNAAGSECEDVDECE-NHLACPGQ-ECV 743
Query: 128 NLPGAFECR-CPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIGSYRCECKPGYTL 184
N PG+F+CR CP G+ L C DVDEC G HG C NT GS+RC C PGY
Sbjct: 744 NSPGSFQCRACPSGHHLHRG--RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA 801
Query: 185 ---RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGG 240
R C DV+EC +G C N G++ C C G++ GP C+DV+EC E
Sbjct: 802 PSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEED 861
Query: 241 MVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDEL-PHPCGRDGNPSCTNTNGG 299
+ C++G C NT GSF C C PG+ D +C DVDEC E P CG + C N+ G
Sbjct: 862 L-CQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCG---SQRCENSPGS 917
Query: 300 YEC--SCGAGWKLVGR-RCVDRDECKEL-PYVCAGGECRNFNGGYVCE--CPAGWRFDKT 353
Y C C G+ C D DEC+E P +C C N G Y C C G++
Sbjct: 918 YRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-PTP 976
Query: 354 AAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMR- 412
C D + C + G H +C C +G R C + E ++
Sbjct: 977 GGGCQDVDE--CRNRSFCG-AHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG 1033
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVC--VGGRCV---NTDGSFRCECPDGYVLAPDGLSCV 467
+C + L C P+ + GRCV + G F P +P +
Sbjct: 1034 VCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGMFPGSQPQAPA-SPVLPARP 1092
Query: 468 DADECALDPRICGNGTC-SNTRGGYECQCSPGFTQGPDQTCVDVDECA----EGRAS-CT 521
P G S R Y +P V EC EG S C
Sbjct: 1093 PPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCR 1152
Query: 522 FR-CHNT-AGSFRCTCPYG---YAVAADGVHCRDIDEC-VQEPRVCPHA-CENVVGSYIC 574
+ C T ++ CP+G A + D RD+DEC + +VC C N Y C
Sbjct: 1153 IQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSC 1212
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTD 634
C GY + + C D +EC ++E C GG C+NT GS+ C C+
Sbjct: 1213 YCSNGYYYHTQRLE----CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRR 1268
Query: 635 CIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWG 694
C+ + + +L G C E T +CCC G AWG
Sbjct: 1269 CVSNESQSLDDNL--GVCWQEVGADLVCSHPRLDR---------QATYTECCCLYGEAWG 1317
Query: 695 SECELCPAPGSPARLDLCTAV 715
+C LCPA S LC +
Sbjct: 1318 MDCALCPAQDSDDFEALCNVL 1338
Score = 269 bits (659), Expect = 3e-71
Identities = 177/498 (35%), Positives = 222/498 (44%), Gaps = 44/498 (8%)
Query: 29 HAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPT 88
H PC+ +P + LC G P + +DEC P LC G C + P
Sbjct: 567 HRVPPPCDLGRCENTPG-SFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPG 625
Query: 89 GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD 148
F+C C G+ DVDEC+ PPC G +C N G+F C CP G+R
Sbjct: 626 SFRCVCPAGFRGSACEE---DVDECAQEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGA 681
Query: 149 ECEDVDECG-DQRICDHGDCRNTIGSYRCECKPGY--TLRENVCRDVDECSRPRPVCRNG 205
C+DVDEC C +G C NT GS++C C G+ + C DVDEC C
Sbjct: 682 PCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNAAGSECEDVDECEN-HLACPGQ 740
Query: 206 TCENLPGAYLCH-CDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRCECAPGY 263
C N PG++ C C G C DV+EC G C +G C NT GSFRC CAPGY
Sbjct: 741 ECVNSPGSFQCRACPSGHHLHRGR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY 799
Query: 264 TLTADGRN--CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRD 319
+ GR C DV+EC E C G C NT+G + C+C G++ G C+D D
Sbjct: 800 RAPS-GRPGPCADVNECLEGDF-CFPHGE--CLNTDGSFACTCAPGYRPGPRGASCLDVD 855
Query: 320 ECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-----ER------KELCYDE 368
EC E +C G C N +G + C CP G R A C+D ER + C +
Sbjct: 856 ECSEED-LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENS 914
Query: 369 WEAGRCHR-ARPLQLARPECCCSEGAAWGRY------CERCP-APDSAEFMRICQGGMGR 420
+ RC R P A PE C + Y +RC P S C G +
Sbjct: 915 PGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGY-Q 973
Query: 421 PNL---TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPR 477
P QD+DECR R C N GSF+C C GY A DG CVD +EC
Sbjct: 974 PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG 1033
Query: 478 ICGNGTCSNTRGGYECQC 495
+CG C N G + C C
Sbjct: 1034 VCGAALCENVEGSFLCVC 1051
Score = 203 bits (496), Expect = 2e-51
Identities = 97/230 (42%), Positives = 120/230 (52%), Gaps = 15/230 (6%)
Query: 430 CRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRG 489
C+ P VC GRC++ + C C G+ L+P G C+D DEC P C G C N+ G
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 541
Query: 490 GYECQCSPGFTQGPDQT-CVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYAVAADGVH 547
+ C C PGF GP C+DVDEC C RC NT GSF C CP GY A G
Sbjct: 542 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 601
Query: 548 CRDIDECVQEPRVCPH-ACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLC 606
C+D+DEC Q P +C AC+N+ GS+ C CP G+R ++ ED++EC ++ C
Sbjct: 602 CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACE-------EDVDECAQEPPPC 654
Query: 607 SGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS---LVSGRCE 653
G C NT GSF C C AGF G C D C RS GRCE
Sbjct: 655 GPGRCDNTAGSFHCACPAGFRSRGPGAPCQD--VDECARSPPPCTYGRCE 702
Score = 124 bits (299), Expect = 1e-27
Identities = 61/123 (49%), Positives = 72/123 (58%), Gaps = 13/123 (10%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ-LCH 796
DVDEC +P CAPGR FRCVCGPG+R P C DVDEC PPPCD C
Sbjct: 520 DVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCE 579
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEKRG 855
NT GS+ C+C GY+ GA+C+DVDEC + C + C N GS+ C C G+ RG
Sbjct: 580 NTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGF--RG 637
Query: 856 DAC 858
AC
Sbjct: 638 SAC 640
Score = 107 bits (258), Expect = 1e-22
Identities = 53/123 (43%), Positives = 66/123 (53%), Gaps = 11/123 (8%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYRPAGE--VCADVDECAVRPPPCDQ-LCH 796
DVDECA P C PGR F C C G+R G C DVDECA PPPC C
Sbjct: 643 DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCE 702
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC-SCEDGYEKRG 855
NT+GS+ C+C G++ + G+ C DVDECE Q C N+ GS++C +C G+
Sbjct: 703 NTEGSFQCVCPMGFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQCRACPSGHHLHR 762
Query: 856 DAC 858
C
Sbjct: 763 GRC 765
Score = 97.5 bits (232), Expect = 2e-19
Identities = 54/123 (43%), Positives = 66/123 (53%), Gaps = 14/123 (11%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYR-PAGEV--CADVDECAVRPPPC--DQ 793
DVDEC++ C P G FRC C PGYR P+G CADV+EC + C
Sbjct: 767 DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNEC-LEGDFCFPHG 825
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C NTDGS+ C C GY GA+C DVDEC + IC+NT+GS+EC C G+
Sbjct: 826 ECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRA 885
Query: 854 RGD 856
D
Sbjct: 886 GPD 888
Score = 97.5 bits (232), Expect = 2e-19
Identities = 54/119 (45%), Positives = 64/119 (53%), Gaps = 13/119 (10%)
Query: 746 ADVDECA----AIP-GLC--APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCH 796
ADV+EC P G C G F C C PGYRP G C DVDEC+ +C
Sbjct: 810 ADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICT 869
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDEC-ERDTHTC-QQICSNTEGSYEC--SCEDGY 851
NTDGS++C+C G+ D A+C DVDEC ER C Q C N+ GSY C C+ GY
Sbjct: 870 NTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGY 928
Score = 95.5 bits (227), Expect = 7e-19
Identities = 47/133 (35%), Positives = 68/133 (51%), Gaps = 7/133 (5%)
Query: 23 CCCSVGHAWGAPC--EACPPRGSPAHTALCGEKPGEYINPVTNET--KPIDECDIM-PQL 77
CCC+VG WG+ C + CP + + +LC G Y+ P + + + +DEC + Q+
Sbjct: 1139 CCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRG-YLAPSGDLSLRRDVDECQLFRDQV 1197
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRC 137
CK G C +T G+ C C +GY + C D DEC+ P C G +CVN G++ C C
Sbjct: 1198 CKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEG-GRCVNTVGSYHCTC 1256
Query: 138 PPGYRLTPSLDEC 150
P L S C
Sbjct: 1257 EPPLVLDGSQRRC 1269
Score = 93.1 bits (221), Expect = 4e-18
Identities = 47/113 (41%), Positives = 56/113 (49%), Gaps = 11/113 (9%)
Query: 751 CAAIPGLCAPGR-------FRCVCGPGYR--PAGEVCADVDECAVRPPPC-DQLCHNTDG 800
C P +C PGR + C C G+R P G C DVDEC PPPC C N+ G
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 541
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYE 852
S+ C+C G+ A C DVDEC R C C NT GS+ C C GY+
Sbjct: 542 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQ 594
Score = 92.7 bits (220), Expect = 5e-18
Identities = 65/198 (32%), Positives = 86/198 (43%), Gaps = 23/198 (11%)
Query: 2 EWNEEDQSCAGAVGVPQTKYLCCCSVGHAWG---APC---EACPPRG-SPAHTALCGEKP 54
E +EED +G + C C GH G A C + C RG + + C P
Sbjct: 856 ECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSP 915
Query: 55 GEY-----INP-----VTNETKPIDEC-DIMPQLCKPGTCHDTPTGFQC--GCDHGYEHD 101
G Y +P +DEC + P++C C +TP ++C CD GY+
Sbjct: 916 GSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-P 974
Query: 102 NTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QR 160
C+DVDEC R C A C NLPG+F+C C GY C DV+EC Q
Sbjct: 975 TPGGGCQDVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG 1033
Query: 161 ICDHGDCRNTIGSYRCEC 178
+C C N GS+ C C
Sbjct: 1034 VCGAALCENVEGSFLCVC 1051
Score = 91.1 bits (216), Expect = 2e-17
Identities = 51/120 (42%), Positives = 62/120 (51%), Gaps = 13/120 (10%)
Query: 747 DVDECAAI-PGLCA-------PGRFRCV--CGPGYRPA-GEVCADVDECAVRP-PPCDQL 794
DVDEC P +C PG +RC C PGY+P G C DVDEC R +
Sbjct: 938 DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAV 997
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEK 853
C N GS+ CLC GYE DG +C DV+ECE C +C N EGS+ C C + E+
Sbjct: 998 CQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEE 1057
Score = 89.8 bits (213), Expect = 4e-17
Identities = 57/131 (43%), Positives = 66/131 (50%), Gaps = 19/131 (14%)
Query: 747 DVDECAAI-PGLC-------APGRFRCV--CGPGYRPAGE-VCADVDECAVRPPP-CD-Q 793
DVDEC P LC +PG +RCV C PGY E C DVDEC P C Q
Sbjct: 894 DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQ 953
Query: 794 LCHNTDGSYDCL--CRTGYELDEDGANCRDVDECE-RDTHTCQQICSNTEGSYECSCEDG 850
C NT GSY C C GY+ G C+DVDEC R +C N GS++C C+ G
Sbjct: 954 RCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQG 1012
Query: 851 YE--KRGDACV 859
YE + G CV
Sbjct: 1013 YEGARDGRHCV 1023
Score = 87.8 bits (208), Expect = 1e-16
Identities = 55/129 (42%), Positives = 67/129 (51%), Gaps = 18/129 (13%)
Query: 747 DVDECA----AIPGLCA--PGRFRCVCGPGYRPAGEV--CADVDECAVRPPP-C-DQLCH 796
DVDEC+ G+C G F C+C PG+R ++ C DVDEC R P C Q C
Sbjct: 853 DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCE 912
Query: 797 NTDGSYDCL--CRTGYELDEDGANCRDVDEC-ERDTHTC-QQICSNTEGSYEC--SCEDG 850
N+ GSY C+ C GY +G C DVDEC E C Q C NT GSY C +C+ G
Sbjct: 913 NSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPG 971
Query: 851 YEKR-GDAC 858
Y+ G C
Sbjct: 972 YQPTPGGGC 980
Score = 85.0 bits (201), Expect = 1e-15
Identities = 47/130 (36%), Positives = 57/130 (43%), Gaps = 7/130 (5%)
Query: 304 CGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVC-----V 358
C G++ V C D DEC C GEC N GGY C CP G+ D + + C +
Sbjct: 277 CPTGFERVNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 335
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSE-GAAWGRYCERCPAPDSAEFMRICQGG 417
E K C+ G C + + CCCS G AWGR C+ CP S F IC G
Sbjct: 336 SEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAG 395
Query: 418 MGRPNLTQDL 427
G DL
Sbjct: 396 PGYHYSASDL 405
Score = 83.8 bits (198), Expect = 2e-15
Identities = 52/126 (41%), Positives = 64/126 (50%), Gaps = 13/126 (10%)
Query: 747 DVDECA---AIPGL-C--APGRFRC-VCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHN 797
DVDEC A PG C +PG F+C C G+ C DVDEC+ PPC C N
Sbjct: 727 DVDECENHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTN 786
Query: 798 TDGSYDCLCRTGYELDEDGAN-CRDVDEC-ERDTHTCQQICSNTEGSYECSCEDGYE--K 853
T+GS+ C C GY C DV+EC E D C NT+GS+ C+C GY
Sbjct: 787 TEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGP 846
Query: 854 RGDACV 859
RG +C+
Sbjct: 847 RGASCL 852
Score = 72.1 bits (169), Expect = 8e-12
Identities = 32/75 (42%), Positives = 40/75 (53%), Gaps = 4/75 (5%)
Query: 202 CRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREG---GMVCRNGRCRNTVGSFRC 257
C NG C +P + C C DG++ CVD+NEC E +C N RC NT GSFRC
Sbjct: 1476 CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC 1535
Query: 258 ECAPGYTLTADGRNC 272
C PG+ T +C
Sbjct: 1536 ICRPGFAPTHQPHHC 1550
Score = 70.9 bits (166), Expect = 2e-11
Identities = 35/88 (39%), Positives = 44/88 (50%), Gaps = 6/88 (6%)
Query: 416 GGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC--- 472
G + P + +EC + D C GRCV F C C DGY L ++CVD +EC
Sbjct: 1456 GSLAEPYEELEAEECGIL-DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEA 1514
Query: 473 -ALDPRICGNGTCSNTRGGYECQCSPGF 499
A P +C N C NT G + C C PGF
Sbjct: 1515 EAASP-LCVNARCLNTDGSFRCICRPGF 1541
Score = 65.7 bits (153), Expect = 7e-10
Identities = 44/145 (30%), Positives = 60/145 (41%), Gaps = 33/145 (22%)
Query: 576 CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
CP G+ R + +CED++EC C G C NT G + C C GF + C
Sbjct: 277 CPTGFERVNG------SCEDVDECATG-GRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 329
Query: 636 IDRRT-----GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCT-L 689
I + G C+R L G C ++TK CCC+ +
Sbjct: 330 ISQHVISEAKGPCFRVLRDGGC--------------------SLPILRNITKQICCCSRV 369
Query: 690 GAAWGSECELCPAPGSPARLDLCTA 714
G AWG C+LCP GS ++C A
Sbjct: 370 GKAWGRGCQLCPPFGSEGFREICPA 394
Score = 63.3 bits (147), Expect = 4e-09
Identities = 36/90 (40%), Positives = 44/90 (48%), Gaps = 6/90 (6%)
Query: 765 CVCGPGY-RPAGEVCA--DVDECAV-RPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANC 819
C G GY P+G++ DVDEC + R C +C NT Y C C GY C
Sbjct: 1168 CPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLEC 1227
Query: 820 RDVDECERDTHTCQ-QICSNTEGSYECSCE 848
D DEC + C+ C NT GSY C+CE
Sbjct: 1228 IDNDECADEEPACEGGRCVNTVGSYHCTCE 1257
Score = 62.9 bits (146), Expect = 5e-09
Identities = 32/78 (41%), Positives = 39/78 (50%), Gaps = 7/78 (8%)
Query: 565 CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQE---DLCSGGVCINTDGSFLCD 621
C V + C+C +GYR + AC DINEC+E E LC C+NTDGSF C
Sbjct: 1481 CVRVPEGFTCRCFDGYRLDM----TRMACVDINECDEAEAASPLCVNARCLNTDGSFRCI 1536
Query: 622 CDAGFEPSEDGTDCIDRR 639
C GF P+ C R
Sbjct: 1537 CRPGFAPTHQPHHCAPAR 1554
Score = 62.1 bits (144), Expect = 8e-09
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 6/87 (6%)
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCTF--- 522
++A+EC + C NG C G+ C+C G+ + CVD++EC E A+
Sbjct: 1465 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
Query: 523 -RCHNTAGSFRCTCPYGYAVAADGVHC 548
RC NT GSFRC C G+A HC
Sbjct: 1524 ARCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 62.1 bits (144), Expect = 8e-09
Identities = 26/62 (41%), Positives = 37/62 (59%), Gaps = 4/62 (6%)
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQR----ICDHGDCRNTIGSYRCECKP 180
+CV +P F CRC GYRL + C D++EC + +C + C NT GS+RC C+P
Sbjct: 1480 RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRP 1539
Query: 181 GY 182
G+
Sbjct: 1540 GF 1541
Score = 61.3 bits (142), Expect = 1e-08
Identities = 31/84 (36%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDEC--SWGRPPCRGMAQC 126
+EC I+ C G C P GF C C GY D T C D++EC + P A+C
Sbjct: 1468 EECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARC 1526
Query: 127 VNLPGAFECRCPPGYRLTPSLDEC 150
+N G+F C C PG+ T C
Sbjct: 1527 LNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 60.5 bits (140), Expect = 2e-08
Identities = 36/110 (32%), Positives = 50/110 (45%), Gaps = 8/110 (7%)
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWGRY-CERCPAP-DSAEFMRI----CQGGM 418
C+ E G C P + CC G AWG + C+ C ++E + C G
Sbjct: 222 CFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGF 281
Query: 419 GRPNLT-QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
R N + +D+DEC C G C NT G + C CPDG++L SC+
Sbjct: 282 ERVNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCI 330
Score = 59.3 bits (137), Expect = 6e-08
Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Query: 219 DDGFKAGPNNDCVDVNECREGGMV--CRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVD 276
+ G AG + + E E G++ C NGRC F C C GY L C D++
Sbjct: 1450 EGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDIN 1509
Query: 277 ECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
ECDE N C NT+G + C C G+
Sbjct: 1510 ECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
Score = 56.4 bits (130), Expect = 4e-07
Identities = 36/104 (34%), Positives = 44/104 (42%), Gaps = 9/104 (8%)
Query: 218 CDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE 277
C GF+ N C DV+EC GG C++G C NT G + C C G+ L + +C
Sbjct: 277 CPTGFER-VNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHV 334
Query: 278 CDELPHPCG---RDGN---PSCTNTNGGYECSCGAGWKLVGRRC 315
E PC RDG P N C C K GR C
Sbjct: 335 ISEAKGPCFRVLRDGGCSLPILRNITKQI-CCCSRVGKAWGRGC 377
Score = 56.0 bits (129), Expect = 5e-07
Identities = 33/85 (38%), Positives = 42/85 (49%), Gaps = 8/85 (9%)
Query: 453 CPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGF-TQGPDQTCVDVD 511
CP G+ +G SC D DECA R C +G C+NTRGGY C C GF +C+
Sbjct: 277 CPTGFERV-NG-SCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQH 333
Query: 512 ECAEGRASCTFRCHNTAGSFRCTCP 536
+E + C FR G C+ P
Sbjct: 334 VISEAKGPC-FRVLRDGG---CSLP 354
Score = 53.2 bits (122), Expect = 4e-06
Identities = 22/48 (45%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
CP G+ CEDVDEC C HG+C NT G Y C C G+ L
Sbjct: 277 CPTGFERVNG--SCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLL 322
Score = 51.6 bits (118), Expect = 1e-05
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 5/76 (6%)
Query: 152 DVDECGDQRICDHGDCRNTIGSYRCECKPGYTL--RENVCRDVDECSRPR---PVCRNGT 206
+ +ECG C +G C + C C GY L C D++EC P+C N
Sbjct: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
Query: 207 CENLPGAYLCHCDDGF 222
C N G++ C C GF
Sbjct: 1526 CLNTDGSFRCICRPGF 1541
Score = 50.4 bits (115), Expect = 3e-05
Identities = 33/114 (28%), Positives = 50/114 (43%), Gaps = 5/114 (4%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGA-PCEACPPR--GSPAHTALCGEKPGEYINPVTNETK 66
CA + +T+ +CC G AWG C+ C R S +A G P + V +
Sbjct: 231 CASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGF-ERVNGSCE 289
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+DEC + C+ G C +T G+ C C G+ D++ C S + PC
Sbjct: 290 DVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPC 342
Score = 47.6 bits (108), Expect = 2e-04
Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 14/86 (16%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYR--PAGEVCADVDEC----AVRPPPCDQ 793
+ +EC + G C GR F C C GYR C D++EC A P +
Sbjct: 1466 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANC 819
C NTDGS+ C+CR G+ +C
Sbjct: 1525 RCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 4/76 (5%)
Query: 780 DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC---ERDTHTCQQI- 835
+ +EC + + C + C C GY LD C D++EC E + C
Sbjct: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
Query: 836 CSNTEGSYECSCEDGY 851
C NT+GS+ C C G+
Sbjct: 1526 CLNTDGSFRCICRPGF 1541
Score = 45.6 bits (103), Expect = 8e-04
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 6/76 (7%)
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNEC 236
C G+ C DVDEC+ C++G C N G Y C C DGF + C+ +
Sbjct: 277 CPTGFERVNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 335
Query: 237 REGGMVC----RNGRC 248
E C R+G C
Sbjct: 336 SEAKGPCFRVLRDGGC 351
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/57 (40%), Positives = 28/57 (49%), Gaps = 4/57 (7%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDEC 150
C G+E N S C DVDEC+ G G +C N G + C CP G+ L S C
Sbjct: 277 CPTGFERVNGS--CEDVDECATGGRCQHG--ECANTRGGYTCVCPDGFLLDSSRSSC 329
Score = 45.2 bits (102), Expect = 0.001
Identities = 20/53 (37%), Positives = 25/53 (47%)
Query: 767 CGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
C G+ C DVDECA C NT G Y C+C G+ LD ++C
Sbjct: 277 CPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 329
Score = 45.2 bits (102), Expect = 0.001
Identities = 29/91 (31%), Positives = 37/91 (40%), Gaps = 3/91 (3%)
Query: 381 QLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ--DLDECRVRPDVCV 438
+L EC +G GR C R P + + M R + DE +CV
Sbjct: 1464 ELEAEECGILDGCTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1522
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
RC+NTDGSFRC C G+ C A
Sbjct: 1523 NARCLNTDGSFRCICRPGFAPTHQPHHCAPA 1553
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/105 (34%), Positives = 50/105 (47%), Gaps = 17/105 (16%)
Query: 750 ECAA-IPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTD--GSYDCLC 806
ECA+ +PGL R + VC G AG + V +C + C + N++ + D C
Sbjct: 230 ECASPLPGL----RTQEVCCRG---AG-LAWGVHDCQL----CSERLGNSERVSAPDGPC 277
Query: 807 RTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
TG+E +C DVDEC C+NT G Y C C DG+
Sbjct: 278 PTGFE--RVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGF 320
Score = 44.0 bits (99), Expect = 0.002
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Query: 495 CSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC 548
C GF + + +C DVDECA G C NT G + C CP G+ + + C
Sbjct: 277 CPTGFER-VNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 329
Score = 43.2 bits (97), Expect = 0.004
Identities = 33/105 (31%), Positives = 40/105 (38%), Gaps = 6/105 (5%)
Query: 480 GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGY 539
G G C G EC SP + C A G C S R + P G
Sbjct: 218 GFGYCFRELRGGEC-ASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGP 276
Query: 540 AVAA-DGVH--CRDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
+ V+ C D+DEC R C H C N G Y C CP+G+
Sbjct: 277 CPTGFERVNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGF 320
Score = 42.7 bits (96), Expect = 0.005
Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 10/102 (9%)
Query: 489 GGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC 548
G Y + + + + C +D C GR C F C C GY + + C
Sbjct: 1452 GSYAGSLAEPYEELEAEECGILDGCTNGR------CVRVPEGFTCRCFDGYRLDMTRMAC 1505
Query: 549 RDIDECVQEPR---VCPHA-CENVVGSYICKCPEGYRRTSAP 586
DI+EC + +C +A C N GS+ C C G+ T P
Sbjct: 1506 VDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQP 1547
Score = 40.3 bits (90), Expect = 0.028
Identities = 17/39 (43%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 23 CCCSVGHAWGAPCEACPPRGSPAHTALCGE-KPGEYINP 60
CCC G AWG C CP + S ALC +P Y P
Sbjct: 1308 CCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPP 1346
Score = 39.1 bits (87), Expect = 0.066
Identities = 29/82 (35%), Positives = 35/82 (42%), Gaps = 7/82 (8%)
Query: 316 VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGR-- 373
++ +EC L C G C G+ C C G+R D T CVD + C DE EA
Sbjct: 1465 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINE--C-DEAEAASPL 1520
Query: 374 CHRARPLQL-ARPECCCSEGAA 394
C AR L C C G A
Sbjct: 1521 CVNARCLNTDGSFRCICRPGFA 1542
Score = 37.5 bits (83), Expect = 0.20
Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 6/65 (9%)
Query: 793 QLCHNTD-GSYDCLCR--TGYELDEDGANCR-DVDECE--RDTHTCQQICSNTEGSYECS 846
Q C T+ Y LC GY + R DVDEC+ RD +C NT Y C
Sbjct: 1154 QQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY 1213
Query: 847 CEDGY 851
C +GY
Sbjct: 1214 CSNGY 1218
>Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding
protein-4 protein.
Length = 1587
Score = 398 bits (980), Expect = e-110
Identities = 227/607 (37%), Positives = 295/607 (48%), Gaps = 55/607 (9%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C G ++P +DEC +P C PG C ++P F+C C G+ + C D
Sbjct: 533 CACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLD 592
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQ-RICDHGDCR 168
VDEC PPC + +C N PG+F C CP GY+ P C+DVDEC +C G C+
Sbjct: 593 VDECHRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGGCK 651
Query: 169 NTIGSYRCECKPGYTLRENVC-RDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA-GP 226
N GS+RC C G+ R + C DVDEC++ P C G C+N G++ C C GF++ GP
Sbjct: 652 NLPGSFRCVCPAGF--RGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGP 709
Query: 227 NNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C DV+EC C GRC NT GSF+C C G+ G C DVDEC+ G
Sbjct: 710 GAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPG 769
Query: 287 RDGNPSCTNTNGGYEC-SCGAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCEC 344
++ C N+ G ++C +C +G L RC D DEC C G C N G + C C
Sbjct: 770 QE----CVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSC 825
Query: 345 PAGWRFDK-TAAVCVDERKELCYDE-WEAGRCHRARPLQLARPECCCSEGAAWGRYCERC 402
G+R C D + L D + G C C C+ G
Sbjct: 826 APGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTD----GSFACTCAPGYR-------- 873
Query: 403 PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPD 462
P P A + + DEC D+C G C NTDGSF C CP G+ PD
Sbjct: 874 PGPRGASCLDV--------------DECS-EEDLCQSGICTNTDGSFECICPPGHRAGPD 918
Query: 463 GLSCVDADEC-ALDPRICGNGTCSNTRGGYEC--QCSPGFTQGPDQTCVDVDECAE-GRA 518
SC+D DEC P +CG+ C N+ G Y C C PG+ GP+ TC DVDEC E G
Sbjct: 919 LASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPE 978
Query: 519 SC-TFRCHNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYIC 574
C RC NT GS+RCT C GY G C+D+DEC HA C+N+ GS+ C
Sbjct: 979 ICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNRSFCGAHAVCQNLPGSFQC 1037
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTD 634
C +GY +D + C D+NECE + +C +C N +GSFLC C E + T
Sbjct: 1038 LCDQGY---EGARDGRH-CVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTG 1093
Query: 635 -CIDRRT 640
C+ RT
Sbjct: 1094 RCVPPRT 1100
Score = 349 bits (858), Expect = 2e-95
Identities = 234/652 (35%), Positives = 302/652 (46%), Gaps = 71/652 (10%)
Query: 19 TKYLCCCS-VGHAWGAPCEACPPRGSPAHTALCGEKPGEYINP--VTNETKPIDECDIMP 75
TK +CCCS VG AWG C+ CPP GS +C PG + + + T+P+ +
Sbjct: 390 TKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRV 449
Query: 76 QLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC 135
L +P T T G+ +H E RP R + + LP
Sbjct: 450 SLSQPRTLPATSRP-----SAGFL---PTHRLEPRPE---PRPDPRPGPE-LPLPSIPAW 497
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL--RENVCRDVD 193
P PS C+ + ++C G C + Y C C G+ L + C DVD
Sbjct: 498 TGPEIPESGPSSGMCQR-----NPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVD 552
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTV 252
EC R P C G CEN PG++ C C GF+AGP +C+DV+EC C GRC NT
Sbjct: 553 ECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTP 612
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
GSF C C GY G +C+DVDEC + P CGR G C N G + C C AG++ G
Sbjct: 613 GSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGG---CKNLPGSFRCVCPAGFR--G 667
Query: 313 RRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKELCYDEWE 370
C D DEC + P C G C N G + C CPAG+R A C D +
Sbjct: 668 SACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCT 727
Query: 371 AGRCHRAR-------PL----QLARPEC-----CCSEGAAWGRYCERCPAPDSAEFMRIC 414
GRC P+ A EC C + A G+ C P R C
Sbjct: 728 YGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQC---RTC 784
Query: 415 QGG--MGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGL--SCVDA 469
G + R T D+DEC C G C NT+GSFRC C GY AP G C D
Sbjct: 785 PSGHHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY-RAPSGRPGPCADV 842
Query: 470 DECALDPRIC-GNGTCSNTRGGYECQCSPGFTQGP-DQTCVDVDECAEGRASCTFRCHNT 527
+EC L+ C +G C NT G + C C+PG+ GP +C+DVDEC+E + C NT
Sbjct: 843 NEC-LEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNT 901
Query: 528 AGSFRCTCPYGYAVAADGVHCRDIDECVQE-PRVC-PHACENVVGSYIC--KCPEGYRRT 583
GSF C CP G+ D C D+DEC + P +C CEN GSY C C GY
Sbjct: 902 DGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYH-- 959
Query: 584 SAPQDSENACEDINECEEQ-EDLCSGGVCINTDGSFLCD--CDAGFEPSEDG 632
+ P E C+D++EC+E ++C C NT GS+ C CD G++P+ G
Sbjct: 960 AGP---EGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG 1008
Score = 289 bits (708), Expect = 4e-77
Identities = 186/498 (37%), Positives = 239/498 (47%), Gaps = 39/498 (7%)
Query: 68 IDECDIMPQLCKP-GTCHDTPTGFQCGCDHGYEHDN-TSHLCRDVDECSWGRPPCRGMAQ 125
+DEC C P G C +T F+C C GY + C DV+EC G C +
Sbjct: 798 VDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEG-DFCFPHGE 856
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
C+N G+F C C PGYR P C DVDEC ++ +C G C NT GS+ C C PG+
Sbjct: 857 CLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAG 916
Query: 186 ENV--CRDVDECSRPRP-VCRNGTCENLPGAYLC--HCDDGFKAGPNNDCVDVNECRE-G 239
++ C DVDEC P +C + CEN PG+Y C CD G+ AGP C DV+EC+E G
Sbjct: 917 PDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYG 976
Query: 240 GMVCRNGRCRNTVGSFRCE--CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTN 297
+C RC NT GS+RC C PGY T G C+DVDEC CG + C N
Sbjct: 977 PEICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNRSF-CG--AHAVCQNLP 1032
Query: 298 GGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECP-AGWRFDKTA 354
G ++C C G++ GR CVD +EC+ L VC C N G ++C CP + FD
Sbjct: 1033 GSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMT 1092
Query: 355 AVCVDERKELCYDEWEAGRCH-------RARPLQLARPECCCSEGAAWGRYCERCPAPDS 407
CV R + + R P L+R +G G C C +
Sbjct: 1093 GRCVPPRTSVGMSPGSQPQAPVSPVLPARPPPPPLSRRPRKPRKGPV-GSGCRECYFDTA 1151
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR---CVNTD-GSFRCECPDGY-VLAPD 462
A C + R N+T C V G R C T+ ++ CP G LAP
Sbjct: 1152 AP--DACDNILAR-NVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPS 1208
Query: 463 G-LSCV-DADECAL-DPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRA 518
G LS D DEC L ++C +G C NT GY C CS G+ + C+D DECA+
Sbjct: 1209 GDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEP 1268
Query: 519 SCT-FRCHNTAGSFRCTC 535
+C RC NT GS+ CTC
Sbjct: 1269 ACEGGRCVNTVGSYHCTC 1286
Score = 278 bits (682), Expect = 5e-74
Identities = 179/506 (35%), Positives = 225/506 (44%), Gaps = 38/506 (7%)
Query: 32 GAPCEACPPRGSPAHTA---LCGEKPGEYINPV--TNETKPIDECDIMPQLCKP-GTCHD 85
GAP C P G +T C PG Y P ++EC + C P G C +
Sbjct: 804 GAP--PCGPHGHCTNTEGSFRCSCAPG-YRAPSGRPGPCADVNEC-LEGDFCFPHGECLN 859
Query: 86 TPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTP 145
T F C C GY C DVDECS C+ C N G+FEC CPPG+R P
Sbjct: 860 TDGSFACTCAPGYRPGPRGASCLDVDECS-EEDLCQS-GICTNTDGSFECICPPGHRAGP 917
Query: 146 SLDECEDVDECGDQ--RICDHGDCRNTIGSYRC--ECKPGYTLR-ENVCRDVDECSRPRP 200
L C DVDEC ++ +C C N+ GSYRC +C PGY E C DVDEC P
Sbjct: 918 DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGP 977
Query: 201 -VCRNGTCENLPGAYLCH--CDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRC 257
+C CEN PG+Y C CD G++ P C DV+ECR + C+N GSF+C
Sbjct: 978 EICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQC 1037
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK----LVGR 313
C GY DGR+C DV+EC+ L CG C N G + C C + + GR
Sbjct: 1038 LCDQGYEGARDGRHCVDVNECETLQGVCGA---ALCENVEGSFLCVCPNSPEEFDPMTGR 1094
Query: 314 RCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEA-G 372
R P P R K V CY + A
Sbjct: 1095 CVPPRTSVGMSPGSQPQAPVSPVLPARPPPPPLSRRPRKPRKGPVGSGCRECYFDTAAPD 1154
Query: 373 RCHRARPLQLARPECCCSEGAAWGRYC--ERCPAPDSAEFMRICQGGMG--RPN----LT 424
C + ECCC+ G WG C ++CP ++AE+ +C G G P+ L
Sbjct: 1155 ACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLR 1214
Query: 425 QDLDECRV-RPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT 483
+D+DEC++ R VC G CVNT + C C +GY L C+D DECA + C G
Sbjct: 1215 RDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGR 1274
Query: 484 CSNTRGGYECQCSPGFT-QGPDQTCV 508
C NT G Y C C P G + CV
Sbjct: 1275 CVNTVGSYHCTCEPPLVLDGSQRRCV 1300
Score = 273 bits (669), Expect = 2e-72
Identities = 218/686 (31%), Positives = 282/686 (41%), Gaps = 71/686 (10%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+DEC P C G C +T FQC C G++ + C DVDEC C G +CV
Sbjct: 716 VDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECE-NHLACPGQ-ECV 773
Query: 128 NLPGAFECR-CPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIGSYRCECKPGYTL 184
N PG+F+CR CP G+ L C DVDEC G HG C NT GS+RC C PGY
Sbjct: 774 NSPGSFQCRTCPSGHHLHRG--RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA 831
Query: 185 ---RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGG 240
R C DV+EC +G C N G++ C C G++ GP C+DV+EC E
Sbjct: 832 PSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEED 891
Query: 241 MVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDEL-PHPCGRDGNPSCTNTNGG 299
+ C++G C NT GSF C C PG+ D +C DVDEC E P CG + C N+ G
Sbjct: 892 L-CQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCG---SQRCENSPGS 947
Query: 300 YEC--SCGAGWKLVGR-RCVDRDECKEL-PYVCAGGECRNFNGGYVCE--CPAGWRFDKT 353
Y C C G+ C D DEC+E P +C C N G Y C C G++
Sbjct: 948 YRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-PTP 1006
Query: 354 AAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCS---EGAAWGRYC---ERCPAPDS 407
C D + C + G H +C C EGA GR+C C
Sbjct: 1007 GGGCQDVDE--CRNRSFCG-AHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG 1063
Query: 408 AEFMRICQGGMGR-----PNLTQDLDECRVRPDVCVGGRC-VNTDGSFRCECPDGYVLAP 461
+C+ G PN ++ D R CV R V + + P VL P
Sbjct: 1064 VCGAALCENVEGSFLCVCPNSPEEFDPMTGR---CVPPRTSVGMSPGSQPQAPVSPVL-P 1119
Query: 462 DGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECA----EGR 517
PR G S R Y +P V EC EG
Sbjct: 1120 ARPPPPPLSRRPRKPRKGPVG--SGCRECYFDTAAPDACDNILARNVTWQECCCTVGEGW 1177
Query: 518 AS-CTFR-CHNT-AGSFRCTCPYG---YAVAADGVHCRDIDEC-VQEPRVCPHA-CENVV 569
S C + C T ++ CP+G A + D RD+DEC + +VC C N
Sbjct: 1178 GSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTA 1237
Query: 570 GSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPS 629
Y C C GY + + C D +EC ++E C GG C+NT GS+ C C+
Sbjct: 1238 PGYSCYCSNGYYYHTQRLE----CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLD 1293
Query: 630 EDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTL 689
C+ + + +L G C E T +CCC
Sbjct: 1294 GSQRRCVSNESQSLDDNL--GVCWQEVGADLVCSHPRLDR---------QATYTECCCLY 1342
Query: 690 GAAWGSECELCPAPGSPARLDLCTAV 715
G AWG +C LCPA S LC +
Sbjct: 1343 GEAWGMDCALCPAQDSDDFEALCNVL 1368
Score = 268 bits (657), Expect = 6e-71
Identities = 177/498 (35%), Positives = 222/498 (44%), Gaps = 44/498 (8%)
Query: 29 HAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPT 88
H PC+ +P + LC G P + +DEC P LC G C + P
Sbjct: 597 HRVPPPCDLGRCENTPG-SFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGGCKNLPG 655
Query: 89 GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD 148
F+C C G+ DVDEC+ PPC G +C N G+F C CP G+R
Sbjct: 656 SFRCVCPAGFRGSACEE---DVDECAQEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGA 711
Query: 149 ECEDVDECG-DQRICDHGDCRNTIGSYRCECKPGY--TLRENVCRDVDECSRPRPVCRNG 205
C+DVDEC C +G C NT GS++C C G+ + C DVDEC C
Sbjct: 712 PCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECEN-HLACPGQ 770
Query: 206 TCENLPGAYLCH-CDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRCECAPGY 263
C N PG++ C C G C DV+EC G C +G C NT GSFRC CAPGY
Sbjct: 771 ECVNSPGSFQCRTCPSGHHLHRGR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY 829
Query: 264 TLTADGRN--CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRD 319
+ GR C DV+EC E C G C NT+G + C+C G++ G C+D D
Sbjct: 830 RAPS-GRPGPCADVNECLEGDF-CFPHGE--CLNTDGSFACTCAPGYRPGPRGASCLDVD 885
Query: 320 ECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-----ER------KELCYDE 368
EC E +C G C N +G + C CP G R A C+D ER + C +
Sbjct: 886 ECSEED-LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENS 944
Query: 369 WEAGRCHR-ARPLQLARPECCCSEGAAWGRY------CERCP-APDSAEFMRICQGGMGR 420
+ RC R P A PE C + Y +RC P S C G +
Sbjct: 945 PGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGY-Q 1003
Query: 421 PNL---TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPR 477
P QD+DECR R C N GSF+C C GY A DG CVD +EC
Sbjct: 1004 PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG 1063
Query: 478 ICGNGTCSNTRGGYECQC 495
+CG C N G + C C
Sbjct: 1064 VCGAALCENVEGSFLCVC 1081
Score = 202 bits (492), Expect = 6e-51
Identities = 96/230 (41%), Positives = 119/230 (51%), Gaps = 15/230 (6%)
Query: 430 CRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRG 489
C+ P VC GRC++ + C C G+ L+P G C+D DEC P C G C N+ G
Sbjct: 512 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 571
Query: 490 GYECQCSPGFTQGPDQT-CVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYAVAADGVH 547
+ C C PGF GP C+DVDEC C RC NT GSF C CP GY A G
Sbjct: 572 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 631
Query: 548 CRDIDECVQEPRVCPH-ACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLC 606
C+D+DEC Q P +C C+N+ GS+ C CP G+R ++ ED++EC ++ C
Sbjct: 632 CQDVDECTQSPGLCGRGGCKNLPGSFRCVCPAGFRGSACE-------EDVDECAQEPPPC 684
Query: 607 SGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS---LVSGRCE 653
G C NT GSF C C AGF G C D C RS GRCE
Sbjct: 685 GPGRCDNTAGSFHCACPAGFRSRGPGAPCQD--VDECARSPPPCTYGRCE 732
Score = 123 bits (296), Expect = 3e-27
Identities = 61/123 (49%), Positives = 72/123 (58%), Gaps = 13/123 (10%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ-LCH 796
DVDEC +P CAPGR FRCVCGPG+R P C DVDEC PPPCD C
Sbjct: 550 DVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCE 609
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEKRG 855
NT GS+ C+C GY+ GA+C+DVDEC + C + C N GS+ C C G+ RG
Sbjct: 610 NTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGGCKNLPGSFRCVCPAGF--RG 667
Query: 856 DAC 858
AC
Sbjct: 668 SAC 670
Score = 107 bits (258), Expect = 1e-22
Identities = 53/123 (43%), Positives = 66/123 (53%), Gaps = 11/123 (8%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYRPAGE--VCADVDECAVRPPPCDQ-LCH 796
DVDECA P C PGR F C C G+R G C DVDECA PPPC C
Sbjct: 673 DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCE 732
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC-SCEDGYEKRG 855
NT+GS+ C+C G++ + G+ C DVDECE Q C N+ GS++C +C G+
Sbjct: 733 NTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHR 792
Query: 856 DAC 858
C
Sbjct: 793 GRC 795
Score = 102 bits (244), Expect = 6e-21
Identities = 115/408 (28%), Positives = 152/408 (37%), Gaps = 53/408 (12%)
Query: 2 EWNEEDQSCAGAVGVPQTKYLCCCSVGHAWG---APC---EACPPRG-SPAHTALCGEKP 54
E +EED +G + C C GH G A C + C RG + + C P
Sbjct: 886 ECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSP 945
Query: 55 GEY-----INP-----VTNETKPIDEC-DIMPQLCKPGTCHDTPTGFQC--GCDHGYEHD 101
G Y +P +DEC + P++C C +TP ++C CD GY+
Sbjct: 946 GSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-P 1004
Query: 102 NTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QR 160
C+DVDEC R C A C NLPG+F+C C GY C DV+EC Q
Sbjct: 1005 TPGGGCQDVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG 1063
Query: 161 ICDHGDCRNTIGSYRCEC---------KPGYTLRENVCRDVDECSRPRPVCRNGTCENLP 211
+C C N GS+ C C G + + S+P+ P
Sbjct: 1064 VCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSVGMSPGSQPQAPVSPVLPARPP 1123
Query: 212 GAYLCHCDDGFKAGP-NNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
L + GP + C + C N RN C C G G
Sbjct: 1124 PPPLSRRPRKPRKGPVGSGCRECYFDTAAPDACDNILARNVTWQ-ECCCTVG---EGWGS 1179
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKEL-PYVCA 329
CR + +C P + C + GY G L RR D DEC+ VC
Sbjct: 1180 GCR-IQQC---PGTETAEYQSLCPH-GRGYLAPSG---DLSLRR--DVDECQLFRDQVCK 1229
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDE---WEAGRC 374
G C N GY C C G+ + C+D + C DE E GRC
Sbjct: 1230 SGVCVNTAPGYSCYCSNGYYYHTQRLECID--NDECADEEPACEGGRC 1275
Score = 97.5 bits (232), Expect = 2e-19
Identities = 54/123 (43%), Positives = 66/123 (53%), Gaps = 14/123 (11%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYR-PAGEV--CADVDECAVRPPPC--DQ 793
DVDEC++ C P G FRC C PGYR P+G CADV+EC + C
Sbjct: 797 DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNEC-LEGDFCFPHG 855
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C NTDGS+ C C GY GA+C DVDEC + IC+NT+GS+EC C G+
Sbjct: 856 ECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRA 915
Query: 854 RGD 856
D
Sbjct: 916 GPD 918
Score = 97.5 bits (232), Expect = 2e-19
Identities = 54/119 (45%), Positives = 64/119 (53%), Gaps = 13/119 (10%)
Query: 746 ADVDECA----AIP-GLC--APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCH 796
ADV+EC P G C G F C C PGYRP G C DVDEC+ +C
Sbjct: 840 ADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICT 899
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDEC-ERDTHTC-QQICSNTEGSYEC--SCEDGY 851
NTDGS++C+C G+ D A+C DVDEC ER C Q C N+ GSY C C+ GY
Sbjct: 900 NTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGY 958
Score = 95.5 bits (227), Expect = 7e-19
Identities = 47/133 (35%), Positives = 68/133 (51%), Gaps = 7/133 (5%)
Query: 23 CCCSVGHAWGAPC--EACPPRGSPAHTALCGEKPGEYINPVTNET--KPIDECDIM-PQL 77
CCC+VG WG+ C + CP + + +LC G Y+ P + + + +DEC + Q+
Sbjct: 1169 CCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRG-YLAPSGDLSLRRDVDECQLFRDQV 1227
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRC 137
CK G C +T G+ C C +GY + C D DEC+ P C G +CVN G++ C C
Sbjct: 1228 CKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEG-GRCVNTVGSYHCTC 1286
Query: 138 PPGYRLTPSLDEC 150
P L S C
Sbjct: 1287 EPPLVLDGSQRRC 1299
Score = 93.1 bits (221), Expect = 4e-18
Identities = 47/113 (41%), Positives = 56/113 (49%), Gaps = 11/113 (9%)
Query: 751 CAAIPGLCAPGR-------FRCVCGPGYR--PAGEVCADVDECAVRPPPC-DQLCHNTDG 800
C P +C PGR + C C G+R P G C DVDEC PPPC C N+ G
Sbjct: 512 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 571
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYE 852
S+ C+C G+ A C DVDEC R C C NT GS+ C C GY+
Sbjct: 572 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQ 624
Score = 91.1 bits (216), Expect = 2e-17
Identities = 51/120 (42%), Positives = 62/120 (51%), Gaps = 13/120 (10%)
Query: 747 DVDECAAI-PGLCA-------PGRFRCV--CGPGYRPA-GEVCADVDECAVRP-PPCDQL 794
DVDEC P +C PG +RC C PGY+P G C DVDEC R +
Sbjct: 968 DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAV 1027
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEK 853
C N GS+ CLC GYE DG +C DV+ECE C +C N EGS+ C C + E+
Sbjct: 1028 CQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEE 1087
Score = 89.8 bits (213), Expect = 4e-17
Identities = 57/131 (43%), Positives = 66/131 (50%), Gaps = 19/131 (14%)
Query: 747 DVDECAAI-PGLC-------APGRFRCV--CGPGYRPAGE-VCADVDECAVRPPP-CD-Q 793
DVDEC P LC +PG +RCV C PGY E C DVDEC P C Q
Sbjct: 924 DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQ 983
Query: 794 LCHNTDGSYDCL--CRTGYELDEDGANCRDVDECE-RDTHTCQQICSNTEGSYECSCEDG 850
C NT GSY C C GY+ G C+DVDEC R +C N GS++C C+ G
Sbjct: 984 RCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQG 1042
Query: 851 YE--KRGDACV 859
YE + G CV
Sbjct: 1043 YEGARDGRHCV 1053
Score = 87.8 bits (208), Expect = 1e-16
Identities = 55/129 (42%), Positives = 67/129 (51%), Gaps = 18/129 (13%)
Query: 747 DVDECA----AIPGLCA--PGRFRCVCGPGYRPAGEV--CADVDECAVRPPP-C-DQLCH 796
DVDEC+ G+C G F C+C PG+R ++ C DVDEC R P C Q C
Sbjct: 883 DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCE 942
Query: 797 NTDGSYDCL--CRTGYELDEDGANCRDVDEC-ERDTHTC-QQICSNTEGSYEC--SCEDG 850
N+ GSY C+ C GY +G C DVDEC E C Q C NT GSY C +C+ G
Sbjct: 943 NSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPG 1001
Query: 851 YEKR-GDAC 858
Y+ G C
Sbjct: 1002 YQPTPGGGC 1010
Score = 85.0 bits (201), Expect = 1e-15
Identities = 47/130 (36%), Positives = 57/130 (43%), Gaps = 7/130 (5%)
Query: 304 CGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVC-----V 358
C G++ V C D DEC C GEC N GGY C CP G+ D + + C +
Sbjct: 307 CPTGFERVNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 365
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSE-GAAWGRYCERCPAPDSAEFMRICQGG 417
E K C+ G C + + CCCS G AWGR C+ CP S F IC G
Sbjct: 366 SEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAG 425
Query: 418 MGRPNLTQDL 427
G DL
Sbjct: 426 PGYHYSASDL 435
Score = 83.8 bits (198), Expect = 2e-15
Identities = 52/126 (41%), Positives = 64/126 (50%), Gaps = 13/126 (10%)
Query: 747 DVDECA---AIPGL-C--APGRFRC-VCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHN 797
DVDEC A PG C +PG F+C C G+ C DVDEC+ PPC C N
Sbjct: 757 DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTN 816
Query: 798 TDGSYDCLCRTGYELDEDGAN-CRDVDEC-ERDTHTCQQICSNTEGSYECSCEDGYE--K 853
T+GS+ C C GY C DV+EC E D C NT+GS+ C+C GY
Sbjct: 817 TEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGP 876
Query: 854 RGDACV 859
RG +C+
Sbjct: 877 RGASCL 882
Score = 69.3 bits (162), Expect = 5e-11
Identities = 31/75 (41%), Positives = 39/75 (52%), Gaps = 4/75 (5%)
Query: 202 CRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREG---GMVCRNGRCRNTVGSFRC 257
C N C +P + C C DG++ CVD+NEC E +C N RC NT GSFRC
Sbjct: 1506 CTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC 1565
Query: 258 ECAPGYTLTADGRNC 272
C PG+ T +C
Sbjct: 1566 ICRPGFAPTHQPHHC 1580
Score = 68.1 bits (159), Expect = 1e-10
Identities = 34/88 (38%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 416 GGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC--- 472
G + P + +EC + D C RCV F C C DGY L ++CVD +EC
Sbjct: 1486 GSLAEPYEELEAEECGIL-DGCTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEA 1544
Query: 473 -ALDPRICGNGTCSNTRGGYECQCSPGF 499
A P +C N C NT G + C C PGF
Sbjct: 1545 EAASP-LCVNARCLNTDGSFRCICRPGF 1571
Score = 65.7 bits (153), Expect = 7e-10
Identities = 44/145 (30%), Positives = 60/145 (41%), Gaps = 33/145 (22%)
Query: 576 CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
CP G+ R + +CED++EC C G C NT G + C C GF + C
Sbjct: 307 CPTGFERVNG------SCEDVDECATG-GRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 359
Query: 636 IDRRT-----GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCT-L 689
I + G C+R L G C ++TK CCC+ +
Sbjct: 360 ISQHVISEAKGPCFRVLRDGGC--------------------SLPILRNITKQICCCSRV 399
Query: 690 GAAWGSECELCPAPGSPARLDLCTA 714
G AWG C+LCP GS ++C A
Sbjct: 400 GKAWGRGCQLCPPFGSEGFREICPA 424
Score = 63.3 bits (147), Expect = 4e-09
Identities = 36/90 (40%), Positives = 44/90 (48%), Gaps = 6/90 (6%)
Query: 765 CVCGPGY-RPAGEVCA--DVDECAV-RPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANC 819
C G GY P+G++ DVDEC + R C +C NT Y C C GY C
Sbjct: 1198 CPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLEC 1257
Query: 820 RDVDECERDTHTCQ-QICSNTEGSYECSCE 848
D DEC + C+ C NT GSY C+CE
Sbjct: 1258 IDNDECADEEPACEGGRCVNTVGSYHCTCE 1287
Score = 62.9 bits (146), Expect = 5e-09
Identities = 32/78 (41%), Positives = 39/78 (50%), Gaps = 7/78 (8%)
Query: 565 CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQE---DLCSGGVCINTDGSFLCD 621
C V + C+C +GYR + AC DINEC+E E LC C+NTDGSF C
Sbjct: 1511 CVRVPEGFTCRCFDGYRLDM----TRMACVDINECDEAEAASPLCVNARCLNTDGSFRCI 1566
Query: 622 CDAGFEPSEDGTDCIDRR 639
C GF P+ C R
Sbjct: 1567 CRPGFAPTHQPHHCAPAR 1584
Score = 62.5 bits (145), Expect = 6e-09
Identities = 49/153 (32%), Positives = 61/153 (39%), Gaps = 28/153 (18%)
Query: 679 HVTKAQCCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXX 738
+VT +CCCT+G WGS C + PG+ + +L P
Sbjct: 1163 NVTWQECCCTVGEGWGSGCRIQQCPGT----ETAEYQSLCPHGRGYLAPSGD-------- 1210
Query: 739 XXXLDVFADVDECAAI------PGLC---APGRFRCVCGPGYRPAGE--VCADVDECAVR 787
L + DVDEC G+C APG + C C GY + C D DECA
Sbjct: 1211 ---LSLRRDVDECQLFRDQVCKSGVCVNTAPG-YSCYCSNGYYYHTQRLECIDNDECADE 1266
Query: 788 PPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANC 819
P C+ C NT GSY C C LD C
Sbjct: 1267 EPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC 1299
Score = 62.1 bits (144), Expect = 8e-09
Identities = 26/62 (41%), Positives = 37/62 (59%), Gaps = 4/62 (6%)
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQR----ICDHGDCRNTIGSYRCECKP 180
+CV +P F CRC GYRL + C D++EC + +C + C NT GS+RC C+P
Sbjct: 1510 RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRP 1569
Query: 181 GY 182
G+
Sbjct: 1570 GF 1571
Score = 60.5 bits (140), Expect = 2e-08
Identities = 36/110 (32%), Positives = 50/110 (45%), Gaps = 8/110 (7%)
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWGRY-CERCPAP-DSAEFMRI----CQGGM 418
C+ E G C P + CC G AWG + C+ C ++E + C G
Sbjct: 252 CFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGF 311
Query: 419 GRPNLT-QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
R N + +D+DEC C G C NT G + C CPDG++L SC+
Sbjct: 312 ERVNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCI 360
Score = 59.3 bits (137), Expect = 6e-08
Identities = 31/87 (35%), Positives = 43/87 (49%), Gaps = 6/87 (6%)
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCTF--- 522
++A+EC + C N C G+ C+C G+ + CVD++EC E A+
Sbjct: 1495 LEAEECGILDG-CTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1553
Query: 523 -RCHNTAGSFRCTCPYGYAVAADGVHC 548
RC NT GSFRC C G+A HC
Sbjct: 1554 ARCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 58.4 bits (135), Expect = 1e-07
Identities = 30/84 (35%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDEC--SWGRPPCRGMAQC 126
+EC I+ C C P GF C C GY D T C D++EC + P A+C
Sbjct: 1498 EECGILDG-CTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARC 1556
Query: 127 VNLPGAFECRCPPGYRLTPSLDEC 150
+N G+F C C PG+ T C
Sbjct: 1557 LNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 56.4 bits (130), Expect = 4e-07
Identities = 36/104 (34%), Positives = 44/104 (42%), Gaps = 9/104 (8%)
Query: 218 CDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE 277
C GF+ N C DV+EC GG C++G C NT G + C C G+ L + +C
Sbjct: 307 CPTGFER-VNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHV 364
Query: 278 CDELPHPCG---RDGN---PSCTNTNGGYECSCGAGWKLVGRRC 315
E PC RDG P N C C K GR C
Sbjct: 365 ISEAKGPCFRVLRDGGCSLPILRNITKQI-CCCSRVGKAWGRGC 407
Score = 56.4 bits (130), Expect = 4e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Query: 219 DDGFKAGPNNDCVDVNECREGGMV--CRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVD 276
+ G AG + + E E G++ C N RC F C C GY L C D++
Sbjct: 1480 EGGSYAGSLAEPYEELEAEECGILDGCTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDIN 1539
Query: 277 ECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
ECDE N C NT+G + C C G+
Sbjct: 1540 ECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1571
Score = 56.0 bits (129), Expect = 5e-07
Identities = 33/85 (38%), Positives = 42/85 (49%), Gaps = 8/85 (9%)
Query: 453 CPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGF-TQGPDQTCVDVD 511
CP G+ +G SC D DECA R C +G C+NTRGGY C C GF +C+
Sbjct: 307 CPTGFERV-NG-SCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQH 363
Query: 512 ECAEGRASCTFRCHNTAGSFRCTCP 536
+E + C FR G C+ P
Sbjct: 364 VISEAKGPC-FRVLRDGG---CSLP 384
Score = 53.2 bits (122), Expect = 4e-06
Identities = 22/48 (45%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
CP G+ CEDVDEC C HG+C NT G Y C C G+ L
Sbjct: 307 CPTGFERVNG--SCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLL 352
Score = 50.4 bits (115), Expect = 3e-05
Identities = 33/114 (28%), Positives = 50/114 (43%), Gaps = 5/114 (4%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGA-PCEACPPR--GSPAHTALCGEKPGEYINPVTNETK 66
CA + +T+ +CC G AWG C+ C R S +A G P + V +
Sbjct: 261 CASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGF-ERVNGSCE 319
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+DEC + C+ G C +T G+ C C G+ D++ C S + PC
Sbjct: 320 DVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPC 372
Score = 48.8 bits (111), Expect = 8e-05
Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 5/76 (6%)
Query: 152 DVDECGDQRICDHGDCRNTIGSYRCECKPGYTL--RENVCRDVDECSRPR---PVCRNGT 206
+ +ECG C + C + C C GY L C D++EC P+C N
Sbjct: 1496 EAEECGILDGCTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1555
Query: 207 CENLPGAYLCHCDDGF 222
C N G++ C C GF
Sbjct: 1556 CLNTDGSFRCICRPGF 1571
Score = 48.4 bits (110), Expect = 1e-04
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 4/76 (5%)
Query: 780 DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC---ERDTHTCQQI- 835
+ +EC + + C + C C GY LD C D++EC E + C
Sbjct: 1496 EAEECGILDGCTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1555
Query: 836 CSNTEGSYECSCEDGY 851
C NT+GS+ C C G+
Sbjct: 1556 CLNTDGSFRCICRPGF 1571
Score = 46.4 bits (105), Expect = 4e-04
Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 6/78 (7%)
Query: 748 VDECAAIPGLCAPGRFRCVCGPGYR--PAGEVCADVDEC----AVRPPPCDQLCHNTDGS 801
+D C + P F C C GYR C D++EC A P + C NTDGS
Sbjct: 1503 LDGCTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGS 1562
Query: 802 YDCLCRTGYELDEDGANC 819
+ C+CR G+ +C
Sbjct: 1563 FRCICRPGFAPTHQPHHC 1580
Score = 45.6 bits (103), Expect = 8e-04
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 6/76 (7%)
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNEC 236
C G+ C DVDEC+ C++G C N G Y C C DGF + C+ +
Sbjct: 307 CPTGFERVNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 365
Query: 237 REGGMVC----RNGRC 248
E C R+G C
Sbjct: 366 SEAKGPCFRVLRDGGC 381
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/57 (40%), Positives = 28/57 (49%), Gaps = 4/57 (7%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDEC 150
C G+E N S C DVDEC+ G G +C N G + C CP G+ L S C
Sbjct: 307 CPTGFERVNGS--CEDVDECATGGRCQHG--ECANTRGGYTCVCPDGFLLDSSRSSC 359
Score = 45.2 bits (102), Expect = 0.001
Identities = 20/53 (37%), Positives = 25/53 (47%)
Query: 767 CGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
C G+ C DVDECA C NT G Y C+C G+ LD ++C
Sbjct: 307 CPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 359
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/105 (34%), Positives = 50/105 (47%), Gaps = 17/105 (16%)
Query: 750 ECAA-IPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTD--GSYDCLC 806
ECA+ +PGL R + VC G AG + V +C + C + N++ + D C
Sbjct: 260 ECASPLPGL----RTQEVCCRG---AG-LAWGVHDCQL----CSERLGNSERVSAPDGPC 307
Query: 807 RTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
TG+E +C DVDEC C+NT G Y C C DG+
Sbjct: 308 PTGFE--RVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGF 350
Score = 44.0 bits (99), Expect = 0.002
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Query: 495 CSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC 548
C GF + + +C DVDECA G C NT G + C CP G+ + + C
Sbjct: 307 CPTGFER-VNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 359
Score = 43.6 bits (98), Expect = 0.003
Identities = 18/44 (40%), Positives = 22/44 (50%)
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
+ DE +CV RC+NTDGSFRC C G+ C A
Sbjct: 1540 ECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPA 1583
Score = 43.2 bits (97), Expect = 0.004
Identities = 33/105 (31%), Positives = 40/105 (38%), Gaps = 6/105 (5%)
Query: 480 GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGY 539
G G C G EC SP + C A G C S R + P G
Sbjct: 248 GFGYCFRELRGGEC-ASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGP 306
Query: 540 AVAA-DGVH--CRDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
+ V+ C D+DEC R C H C N G Y C CP+G+
Sbjct: 307 CPTGFERVNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGF 350
Score = 42.3 bits (95), Expect = 0.007
Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 508 VDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPR---VCPHA 564
++ +EC RC F C C GY + + C DI+EC + +C +A
Sbjct: 1495 LEAEECGILDGCTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554
Query: 565 -CENVVGSYICKCPEGYRRTSAP 586
C N GS+ C C G+ T P
Sbjct: 1555 RCLNTDGSFRCICRPGFAPTHQP 1577
Score = 40.3 bits (90), Expect = 0.028
Identities = 17/39 (43%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 23 CCCSVGHAWGAPCEACPPRGSPAHTALCGE-KPGEYINP 60
CCC G AWG C CP + S ALC +P Y P
Sbjct: 1338 CCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPP 1376
Score = 37.5 bits (83), Expect = 0.20
Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 6/65 (9%)
Query: 793 QLCHNTD-GSYDCLCR--TGYELDEDGANCR-DVDECE--RDTHTCQQICSNTEGSYECS 846
Q C T+ Y LC GY + R DVDEC+ RD +C NT Y C
Sbjct: 1184 QQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY 1243
Query: 847 CEDGY 851
C +GY
Sbjct: 1244 CSNGY 1248
Score = 36.3 bits (80), Expect = 0.46
Identities = 28/82 (34%), Positives = 34/82 (41%), Gaps = 7/82 (8%)
Query: 316 VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGR-- 373
++ +EC L C C G+ C C G+R D T CVD + C DE EA
Sbjct: 1495 LEAEECGILDG-CTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINE--C-DEAEAASPL 1550
Query: 374 CHRARPLQL-ARPECCCSEGAA 394
C AR L C C G A
Sbjct: 1551 CVNARCLNTDGSFRCICRPGFA 1572
>AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein.
Length = 1382
Score = 386 bits (949), Expect = e-106
Identities = 218/548 (39%), Positives = 283/548 (51%), Gaps = 51/548 (9%)
Query: 38 CPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGT--CHDTPTGFQCGCD 95
C P G P ++ C PG +P ++EC+ P C PG C +T + C C+
Sbjct: 669 CVP-GPPDYSCHCN--PGYRSHPQHRYCVDVNECEAEP--CGPGRGICMNTGGSYNCHCN 723
Query: 96 HGYE-HDNTS-HLCRDVDECSWGRPP-CRGMAQCVNLPGAFECRCPPGYRLTPSLDE-CE 151
GY H C D++EC+ +P C C+N PG ++C C PGYRL S CE
Sbjct: 724 RGYRLHVGAGGRSCVDLNECA--KPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCE 781
Query: 152 DVDECGDQRICDHGDCRNTIGSYRC-ECKPGYTLREN-VCRDVDECSRPRPVCRNGTCEN 209
D+DEC D C G C N GS++C C+PGY + CRDV+EC+ P C G CEN
Sbjct: 782 DIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSP-CSPGWCEN 840
Query: 210 LPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTAD 268
LPG++ C C G+ P+ C+DV+EC E G VC NG C NT GSF+C+C GY L+ D
Sbjct: 841 LPGSFRCTCAQGYAPAPDGRSCLDVDEC-EAGDVCDNGICSNTPGSFQCQCLSGYHLSRD 899
Query: 269 GRNCRDVDECDELPHPC-GRDGNPSCTNTNGGYECSCGAGWKLV-GRRCVDRDECKELPY 326
+C D+DECD P C G D C NTNG Y C C G +LV GR+C D DEC + P
Sbjct: 900 RSHCEDIDECD-FPAACIGGD----CINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPS 954
Query: 327 VC-AGGECRNFNGGYVCECPAGWRFDKTAAVCVD----ERKELCYDEW-EAGRCHRARPL 380
+C G C+N G YVC C G+ + C + K+ CY + + C
Sbjct: 955 LCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLAT 1014
Query: 381 QLARPECCCSEGAAWGRYCE--RCPAPDSAEFMRICQGGMGRP---NLT-------QDLD 428
+ + ECCCS GA WG +CE CP SAEF +C G G N+ +D+D
Sbjct: 1015 NVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDID 1074
Query: 429 ECRV-RPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNT 487
EC + ++C G+CVNT + C C G+ + L CVD DEC LD C NG C NT
Sbjct: 1075 ECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDEC-LDESNCRNGVCENT 1133
Query: 488 RGGYECQCSPGFTQGPDQ-TC-----VDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAV 541
RGGY C C+P P Q C +DVDEC + A RC N GS+RC C +
Sbjct: 1134 RGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCECRPPWVP 1193
Query: 542 AADGVHCR 549
G C+
Sbjct: 1194 GPSGRDCQ 1201
Score = 308 bits (757), Expect = 4e-83
Identities = 204/575 (35%), Positives = 255/575 (44%), Gaps = 49/575 (8%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC + +C G C P + C C+ GY C DV+EC P G C+N
Sbjct: 655 DECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECE-AEPCGPGRGICMN 713
Query: 129 LPGAFECRCPPGYRLTPSLD--ECEDVDECGDQRIC-DHGDCRNTIGSYRCECKPGYTL- 184
G++ C C GYRL C D++EC +C D G C N G Y+C C PGY L
Sbjct: 714 TGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLK 773
Query: 185 --RENVCRDVDECSRPRPVCRNGTCENLPGAYLC-HCDDGFKAGPNNDCVDVNECREGGM 241
R VC D+DEC P C +G CEN PG++ C C G+++ C DVNEC EG
Sbjct: 774 ASRPPVCEDIDECRDPSS-CPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGS- 831
Query: 242 VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
C G C N GSFRC CA GY DGR+C DVDEC E C N C+NT G ++
Sbjct: 832 PCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDEC-EAGDVC---DNGICSNTPGSFQ 887
Query: 302 CSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD 359
C C +G+ L R C D DEC + P C GG+C N NG Y C CP G R C D
Sbjct: 888 CQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGDCINTNGSYRCLCPQGHRL-VGGRKCQD 945
Query: 360 ERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQ---- 415
+ C + H A C C EG + C + + C
Sbjct: 946 --IDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFD 1003
Query: 416 -----GGMGRPNLTQDLDECRVRP---DVCVGGRC-VNTDGSFRCECPDGYVLAPD---- 462
+ N+TQ C + D C C V + F CPDG D
Sbjct: 1004 DTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIV 1063
Query: 463 --GLSC-VDADECAL-DPRICGNGTCSNTRGGYECQCSPGF-TQGPDQTCVDVDECAEGR 517
G+ D DEC L IC G C NT+ GYEC C GF G CVDVDEC +
Sbjct: 1064 NYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDES 1123
Query: 518 ASCTFRCHNTAGSFRCTC--PYGYAVAAD---GVHCRDIDECVQEPRVC-PHACENVVGS 571
C NT G +RC C P Y+ A D+DEC Q+P C P C N+ GS
Sbjct: 1124 NCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDEC-QDPAACRPGRCVNLPGS 1182
Query: 572 YICKCPEGYRRTSAPQDSENACEDINECEEQEDLC 606
Y C+C + + +D + E+ D+C
Sbjct: 1183 YRCECRPPWVPGPSGRDCQLPESPAERAPERRDVC 1217
Score = 254 bits (623), Expect = 7e-67
Identities = 182/596 (30%), Positives = 240/596 (40%), Gaps = 83/596 (13%)
Query: 274 DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGG 331
+ DEC + CG C Y C C G++ R CVD +EC+ P G
Sbjct: 653 ETDECRLNQNICGHG---ECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRG 709
Query: 332 ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSE 391
C N G Y C C G+R A C D E + H C +
Sbjct: 710 ICMNTGGSYNCHCNRGYRLHVGAG------GRSCVDLNECAKPH------------LCGD 751
Query: 392 GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRC 451
G +C P + RP + +D+DECR P C G+C N GSF+C
Sbjct: 752 GG----FCINFPGHYKCNCYPGYRLKASRPPVCEDIDECR-DPSSCPDGKCENKPGSFKC 806
Query: 452 -ECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVD 509
C GY + G +C D +ECA + C G C N G + C C+ G+ PD ++C+D
Sbjct: 807 IACQPGY-RSQGGGACRDVNECA-EGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLD 864
Query: 510 VDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENV 568
VDEC G C NT GSF+C C GY ++ D HC DIDEC P C C N
Sbjct: 865 VDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGDCINT 923
Query: 569 VGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFE 627
GSY C CP+G+R + C+DI+EC + LC G C N GS++C CD GF
Sbjct: 924 NGSYRCLCPQGHRLVGGRK-----CQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFT 978
Query: 628 PSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCC 687
P++D C + +P +VT+ +CCC
Sbjct: 979 PTQDQHGCEEVE-------------QPHHKKECYLNFDDTVFCDSVLAT--NVTQQECCC 1023
Query: 688 TLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFAD 747
+LGA WG CE+ P P V + + D
Sbjct: 1024 SLGAGWGDHCEIYPCP-----------VYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRD 1072
Query: 748 VDECAAIPG-LCAPGR-------FRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHN 797
+DEC +C G+ + C C G+ G + C DVDEC + +C N
Sbjct: 1073 IDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCEN 1132
Query: 798 TDGSYDCLCRTGYELDEDGANC-----RDVDECERDTHTCQQ-ICSNTEGSYECSC 847
T G Y C C E C DVDEC+ D C+ C N GSY C C
Sbjct: 1133 TRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQ-DPAACRPGRCVNLPGSYRCEC 1187
Score = 245 bits (600), Expect = 5e-64
Identities = 147/400 (36%), Positives = 198/400 (49%), Gaps = 53/400 (13%)
Query: 232 DVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNP 291
+ +ECR +C +G C + C C PGY R C DV+EC+ PCG G
Sbjct: 653 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECE--AEPCG-PGRG 709
Query: 292 SCTNTNGGYECSCGAGWKL----VGRRCVDRDECKELPYVCA-GGECRNFNGGYVCECPA 346
C NT G Y C C G++L GR CVD +EC + P++C GG C NF G Y C C
Sbjct: 710 ICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAK-PHLCGDGGFCINFPGHYKCNCYP 768
Query: 347 GWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPD 406
G+R + R +C D + R C +G CE P
Sbjct: 769 GYRLKAS-------RPPVCED------------IDECRDPSSCPDGK-----CEN--KPG 802
Query: 407 SAEFMRICQGGMGRP--NLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
S + + CQ G +D++EC C G C N GSFRC C GY APDG
Sbjct: 803 SFKCI-ACQPGYRSQGGGACRDVNEC-AEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGR 860
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFR 523
SC+D DEC +C NG CSNT G ++CQC G+ D++ C D+DEC A
Sbjct: 861 SCLDVDECEAGD-VCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGD 919
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC-PH-ACENVVGSYICKCPEGYR 581
C NT GS+RC CP G+ + G C+DIDEC Q+P +C PH AC+N+ GSY+C C EG+
Sbjct: 920 CINTNGSYRCLCPQGHRLVG-GRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGF- 977
Query: 582 RTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCD 621
P ++ CE++ + +++ C +N D + CD
Sbjct: 978 ---TPTQDQHGCEEVEQPHHKKE-C----YLNFDDTVFCD 1009
Score = 235 bits (574), Expect = 6e-61
Identities = 198/671 (29%), Positives = 267/671 (39%), Gaps = 86/671 (12%)
Query: 7 DQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETK 66
+ C + T+ LCCCSVG AWGA C+ CP G+ A +C G +I +++T
Sbjct: 491 EHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHI-LTSHQTL 549
Query: 67 PID-ECDIMPQL-----CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
I E D L KP ++P+ D E T+ + P
Sbjct: 550 TIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPT 609
Query: 121 RGMAQCVNLPGAFECRCPPGYR-----LTPSLDECE-------DVDECG-DQRICDHGDC 167
P PP R L PS E + DEC +Q IC HG+C
Sbjct: 610 ATTTPARPYPELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGEC 669
Query: 168 RNTIGSYRCECKPGYTL--RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK-- 223
Y C C PGY + C DV+EC G C N G+Y CHC+ G++
Sbjct: 670 VPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLH 729
Query: 224 -AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRN-CRDVDECDEL 281
CVD+NEC + + G C N G ++C C PGY L A C D+DEC +
Sbjct: 730 VGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRD- 788
Query: 282 PHPCGRDGNPSCTNTNGGYEC-SCGAGWKLV-GRRCVDRDECKELPYVCAGGECRNFNGG 339
P C DG C N G ++C +C G++ G C D +EC E C+ G C N G
Sbjct: 789 PSSC-PDG--KCENKPGSFKCIACQPGYRSQGGGACRDVNECAE-GSPCSPGWCENLPGS 844
Query: 340 YVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYC 399
+ C C G+ C+D + D + G C P +C C G R
Sbjct: 845 FRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNT-PGSF---QCQCLSGYHLSRDR 900
Query: 400 ERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVL 459
C D +F C G G C+NT+GS+RC CP G+ L
Sbjct: 901 SHCEDIDECDFPAACIG-----------------------GDCINTNGSYRCLCPQGHRL 937
Query: 460 APDGLSCVDADECALDPRIC-GNGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVD------ 511
G C D DEC+ DP +C +G C N +G Y C C GFT DQ C +V+
Sbjct: 938 V-GGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKK 996
Query: 512 EC---AEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENV 568
EC + C C C G A G HC E CP +
Sbjct: 997 ECYLNFDDTVFCDSVLATNVTQQECCCSLG---AGWGDHC--------EIYPCP-VYSSA 1044
Query: 569 VGSYICKCPEGYRR-TSAPQDSENACEDINECE-EQEDLCSGGVCINTDGSFLCDCDAGF 626
+C +GY + + A DI+EC ++C G C+NT + C C GF
Sbjct: 1045 EFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGF 1104
Query: 627 EPSEDGTDCID 637
+ +C+D
Sbjct: 1105 YYDGNLLECVD 1115
Score = 233 bits (571), Expect = 1e-60
Identities = 183/590 (31%), Positives = 245/590 (41%), Gaps = 70/590 (11%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRC 137
C PG C + P F+C C GY C DVDEC G G+ C N PG+F+C+C
Sbjct: 833 CSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGI--CSNTPGSFQCQC 890
Query: 138 PPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL-RENVCRDVDECS 196
GY L+ CED+DEC C GDC NT GSYRC C G+ L C+D+DECS
Sbjct: 891 LSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECS 950
Query: 197 RPRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCR-NTVGS 254
+ +C +G C+NL G+Y+C CD+GF P D + C E C N +
Sbjct: 951 QDPSLCLPHGACKNLQGSYVCVCDEGFT--PTQD---QHGCEEVEQPHHKKECYLNFDDT 1005
Query: 255 FRCECAPGYTLTADGRNCRDV----DECDELPHPC--GRDGNPSCTNTNGGYECSCGAGW 308
C+ +T C D C+ P P + + C + G + + +
Sbjct: 1006 VFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNY 1065
Query: 309 KLVGRRCVDRDECKEL-PYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYD 367
+ R D DEC +C G+C N GY C C G+ +D CVD + L
Sbjct: 1066 GIPAHR--DIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDES 1123
Query: 368 EWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDL 427
G C R C C+ A + +C +P+ D+
Sbjct: 1124 NCRNGVCENTR----GGYRCACTPPAEYSPAQRQCLSPEE-----------------MDV 1162
Query: 428 DECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNT 487
DEC+ P C GRCVN GS+RCEC +V P G C E + C +
Sbjct: 1163 DECQ-DPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDC-QLPESPAERAPERRDVCWSQ 1220
Query: 488 RGGYECQCSPGFTQGPDQTCVDVDECAEGR---ASCTFRCHNTAGSFRCTCPYGYAVAAD 544
RG + C+ G GP T D C +GR A C AGS CP + +
Sbjct: 1221 RGE-DGMCA-GPLAGPALTFDDCC-CRQGRGWGAQCRPCPPRGAGSH---CPTSQSESNS 1274
Query: 545 ---------GVHCRDIDECVQEPRVC---PHACENVVGSYICKCPEGYRRTSAPQDSENA 592
G RD D ++ C C G +C+CP G++ + S
Sbjct: 1275 FWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDA----SRAR 1330
Query: 593 CEDINECEEQED---LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRR 639
C DI+EC E LC C+NT GSF C C AGF S C+ +R
Sbjct: 1331 CVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQR 1380
Score = 203 bits (495), Expect = 2e-51
Identities = 164/555 (29%), Positives = 230/555 (41%), Gaps = 89/555 (16%)
Query: 21 YLCCCSVGHAWGAPCEACPP-----RGSPAHTALCGEKPGEY---------INPVTNETK 66
+ C C+ G+A +C G +C PG + ++ + +
Sbjct: 845 FRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCE 904
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
IDECD P C G C +T ++C C G+ C+D+DECS C C
Sbjct: 905 DIDECDF-PAACIGGDCINTNGSYRCLCPQGHRLVG-GRKCQDIDECSQDPSLCLPHGAC 962
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
NL G++ C C G+ T CE+V++ ++ C N + C+ L
Sbjct: 963 KNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKEC----YLNFDDTVFCDS----VLAT 1014
Query: 187 NVCRDVDECSRPR---PVCRNGTCENLPGA-YLCHCDDGFKAGPNNDCV--------DVN 234
NV + CS C C A + C DG +N+ V D++
Sbjct: 1015 NVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDID 1074
Query: 235 ECRE-GGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
EC G +C+ G+C NT + C C G+ + C DVDEC L R+G C
Sbjct: 1075 ECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDEC--LDESNCRNG--VC 1130
Query: 294 TNTNGGYECSCG--AGWKLVGRRCV-----DRDECKELPYVCAGGECRNFNGGYVCECPA 346
NT GGY C+C A + R+C+ D DEC++ P C G C N G Y CEC
Sbjct: 1131 ENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQD-PAACRPGRCVNLPGSYRCECRP 1189
Query: 347 GW---------RFDKTAAVCVDERKELCYDE-WEAGRCHRARPLQ---LARPECCCSEGA 393
W + ++ A ER+++C+ + E G C A PL L +CCC +G
Sbjct: 1190 PWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMC--AGPLAGPALTFDDCCCRQGR 1247
Query: 394 AWGRYCERCPAPDSAEFMRICQGG-----------MGRP-----NLTQDLDECRVRPDVC 437
WG C CP + Q +G+P + +D DECR C
Sbjct: 1248 GWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR-----C 1302
Query: 438 VGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC-ALDPR--ICGNGTCSNTRGGYECQ 494
V GRCV G CECP G+ L CVD DEC L+ R +C + C NT G + C
Sbjct: 1303 VSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCV 1362
Query: 495 CSPGFTQG-PDQTCV 508
C GF + P CV
Sbjct: 1363 CKAGFARSRPHGACV 1377
Score = 159 bits (385), Expect = 5e-38
Identities = 123/386 (31%), Positives = 167/386 (43%), Gaps = 45/386 (11%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCE--ACPPRGSPAHTALCGEKPG-EYINPVTNETK 66
C + T+ CCCS+G WG CE CP S +LC + G N + N
Sbjct: 1008 CDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGI 1067
Query: 67 P----IDECDIM-PQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
P IDEC + ++CK G C +T G++C C G+ +D C DVDEC CR
Sbjct: 1068 PAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDEC-LDESNCR 1126
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDEC-----EDVDECGDQRICDHGDCRNTIGSYRC 176
C N G + C C P +P+ +C DVDEC D C G C N GSYRC
Sbjct: 1127 N-GVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRC 1185
Query: 177 ECKPGYTLRENVCRD--VDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGP-NNDCVDV 233
EC+P + + RD + E R R C + G +DG AGP +
Sbjct: 1186 ECRPPWVPGPS-GRDCQLPESPAERAPERRDVCWSQRG------EDGMCAGPLAGPALTF 1238
Query: 234 NE--CREG---GMVCRNGRCRNTVGSFRCECAP----GYTLTAD---GRNCRDVDECDEL 281
++ CR+G G CR C C + + T+ G+ RD D +E
Sbjct: 1239 DDCCCRQGRGWGAQCR--PCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEED 1296
Query: 282 PHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKEL---PYVCAGGECRNF 336
C R + C GG C C G++L RCVD DEC+EL +C C N
Sbjct: 1297 SDEC-RCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNT 1355
Query: 337 NGGYVCECPAGWRFDKTAAVCVDERK 362
+G + C C AG+ + CV +R+
Sbjct: 1356 SGSFRCVCKAGFARSRPHGACVPQRR 1381
Score = 111 bits (267), Expect = 1e-23
Identities = 85/323 (26%), Positives = 119/323 (36%), Gaps = 30/323 (9%)
Query: 509 DVDECAE-GRASCTF-RCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
D+DEC G C +C NT + C C G+ + + C D+DEC+ E CE
Sbjct: 1072 DIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCE 1131
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
N G Y C C + A + + E D++EC++ C G C+N GS+ C+C
Sbjct: 1132 NTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPA-ACRPGRCVNLPGSYRCECRPP 1190
Query: 626 FEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXG-HVTKAQ 684
+ P G DC L E G +T
Sbjct: 1191 WVPGPSGRDC----------QLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDD 1240
Query: 685 CCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDV 744
CCC G WG++C CP G+ + C T
Sbjct: 1241 CCCRQGRGWGAQCRPCPPRGAGSH---CP----TSQSESNSFWDTSPLLLGKPPRDEDSS 1293
Query: 745 FADVDECAAIPGLCA--PGRFRCVCGPGYR--PAGEVCADVDECA---VRPPPC-DQLCH 796
D DEC + G C PG C C G++ + C D+DEC R C + C
Sbjct: 1294 EEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCV 1353
Query: 797 NTDGSYDCLCRTGYELDEDGANC 819
NT GS+ C+C+ G+ C
Sbjct: 1354 NTSGSFRCVCKAGFARSRPHGAC 1376
Score = 104 bits (250), Expect = 1e-21
Identities = 51/117 (43%), Positives = 61/117 (52%), Gaps = 8/117 (6%)
Query: 747 DVDECA----AIPGLCA--PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNT 798
DV+ECA PG C PG FRC C GY PA G C DVDEC + +C NT
Sbjct: 823 DVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNT 882
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
GS+ C C +GY L D ++C D+DEC+ C NT GSY C C G+ G
Sbjct: 883 PGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVG 939
Score = 102 bits (244), Expect = 6e-21
Identities = 54/121 (44%), Positives = 64/121 (52%), Gaps = 8/121 (6%)
Query: 744 VFADVDEC---AAIP-GLCA--PGRFRCV-CGPGYRP-AGEVCADVDECAVRPPPCDQLC 795
V D+DEC ++ P G C PG F+C+ C PGYR G C DV+ECA P C
Sbjct: 779 VCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWC 838
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
N GS+ C C GY DG +C DVDECE ICSNT GS++C C GY
Sbjct: 839 ENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSR 898
Query: 856 D 856
D
Sbjct: 899 D 899
Score = 89.4 bits (212), Expect = 5e-17
Identities = 49/132 (37%), Positives = 60/132 (45%), Gaps = 6/132 (4%)
Query: 298 GGYECSCGAGWK-LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
G C G+K L C D +EC +P VC G+C N G Y C CP G +
Sbjct: 414 GEVGADCPQGYKRLNSTHCQDINECA-MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQ 472
Query: 357 CV---DERKELCYDEWEAG-RCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
C+ E K LC+ +C +L R CCCS G AWG C+RCP +A F
Sbjct: 473 CIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKE 532
Query: 413 ICQGGMGRPNLT 424
IC G G LT
Sbjct: 533 ICPAGKGYHILT 544
Score = 85.4 bits (202), Expect = 8e-16
Identities = 48/123 (39%), Positives = 61/123 (49%), Gaps = 16/123 (13%)
Query: 747 DVDECAAIPGLCA--------PGRFRCVCGPGYRPAGE---VCADVDECAVRPPPC-DQL 794
D++ECA P LC PG ++C C PGYR VC D+DEC P C D
Sbjct: 739 DLNECAK-PHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECR-DPSSCPDGK 796
Query: 795 CHNTDGSYDCL-CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C N GS+ C+ C+ GY + G CRDV+EC + C N GS+ C+C GY
Sbjct: 797 CENKPGSFKCIACQPGYR-SQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAP 855
Query: 854 RGD 856
D
Sbjct: 856 APD 858
Score = 83.4 bits (197), Expect = 3e-15
Identities = 44/105 (41%), Positives = 54/105 (51%), Gaps = 10/105 (9%)
Query: 756 GLCAPGR--FRCVCGPGYR--PAGEVCADVDECAVRP-PPCDQLCHNTDGSYDCLCRTGY 810
G C PG + C C PGYR P C DV+EC P P +C NT GSY+C C GY
Sbjct: 667 GECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGY 726
Query: 811 EL--DEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
L G +C D++EC + H C C N G Y+C+C GY
Sbjct: 727 RLHVGAGGRSCVDLNECAK-PHLCGDGGFCINFPGHYKCNCYPGY 770
Score = 82.6 bits (195), Expect = 5e-15
Identities = 49/150 (32%), Positives = 66/150 (44%), Gaps = 11/150 (7%)
Query: 3 WNE--EDQSCAGAVGVPQTKYL-CCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEY-- 57
W++ ED CAG + P + CCC G WGA C CPPRG+ +H + +
Sbjct: 1218 WSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWD 1277
Query: 58 INPVTNETKPIDEC----DIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDEC 113
+P+ P DE D C G C P G C C G++ D + C D+DEC
Sbjct: 1278 TSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDEC 1337
Query: 114 SW--GRPPCRGMAQCVNLPGAFECRCPPGY 141
R +CVN G+F C C G+
Sbjct: 1338 RELNQRGLLCKSERCVNTSGSFRCVCKAGF 1367
Score = 72.1 bits (169), Expect = 8e-12
Identities = 44/147 (29%), Positives = 63/147 (42%), Gaps = 22/147 (14%)
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
V G CP+GY+R ++ C+DINEC +C G C+N GS+ C C G
Sbjct: 412 VRGEVGADCPQGYKRLNSTH-----CQDINECA-MPGVCRHGDCLNNPGSYRCVCPPGHS 465
Query: 628 PSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCC 687
T CI + +SL PE +T+ CCC
Sbjct: 466 LGPSRTQCIADKPEE--KSLCFRLVSPEHQCQHPLTT--------------RLTRQLCCC 509
Query: 688 TLGAAWGSECELCPAPGSPARLDLCTA 714
++G AWG+ C+ CP G+ A ++C A
Sbjct: 510 SVGKAWGARCQRCPTDGTAAFKEICPA 536
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/130 (34%), Positives = 58/130 (44%), Gaps = 19/130 (14%)
Query: 747 DVDEC----AAIPGLC--APGRFRCVCGPGYR-PAGEVCADVDECAVRPPPC--DQLCHN 797
D+DEC A I G C G +RC+C G+R G C D+DEC+ P C C N
Sbjct: 905 DIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKN 964
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVD------ECE---RDTHTCQQICSNTEGSYECSCE 848
GSY C+C G+ +D C +V+ EC DT C + + EC C
Sbjct: 965 LQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCS 1024
Query: 849 DGYEKRGDAC 858
G GD C
Sbjct: 1025 LG-AGWGDHC 1033
Score = 66.1 bits (154), Expect = 5e-10
Identities = 37/95 (38%), Positives = 47/95 (49%), Gaps = 14/95 (14%)
Query: 386 ECCCSEGAAWGRY-CERCP----------APDSAEFMRICQGGMGRPNLT--QDLDECRV 432
+CC S G AWG+ C +CP P E C G R N T QD++EC +
Sbjct: 381 DCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAM 440
Query: 433 RPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
P VC G C+N GS+RC CP G+ L P C+
Sbjct: 441 -PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCI 474
Score = 63.7 bits (148), Expect = 3e-09
Identities = 42/138 (30%), Positives = 59/138 (42%), Gaps = 12/138 (8%)
Query: 75 PQLCKP-GTC-HDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC----VN 128
P KP G C DT CG + C + +WG+ C Q V
Sbjct: 349 PPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGT-AWGQSKCHKCPQLQYTGVQ 407
Query: 129 LPGAFE----CRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
PG CP GY+ S C+D++EC +C HGDC N GSYRC C PG++L
Sbjct: 408 KPGPVRGEVGADCPQGYKRLNST-HCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSL 466
Query: 185 RENVCRDVDECSRPRPVC 202
+ + + + + +C
Sbjct: 467 GPSRTQCIADKPEEKSLC 484
Score = 62.5 bits (145), Expect = 6e-09
Identities = 50/167 (29%), Positives = 69/167 (41%), Gaps = 16/167 (9%)
Query: 180 PGYTLRENVCRDV------DECSRPRPVCRNGTCENLP--GAYLCHCDDGFKAGPNNDCV 231
PG T +E+ C + +C + + G + P G C G+K + C
Sbjct: 374 PGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQ 433
Query: 232 DVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDE----CDELPHPCG 286
D+NEC G VCR+G C N GS+RC C PG++L C D E C L P
Sbjct: 434 DINECAMPG-VCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEH 492
Query: 287 RDGNPSCTN-TNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGE 332
+ +P T T CS G W +RC D +C G+
Sbjct: 493 QCQHPLTTRLTRQLCCCSVGKAWGARCQRC-PTDGTAAFKEICPAGK 538
Score = 56.4 bits (130), Expect = 4e-07
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 447 GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT 506
G +CP GY + C D +ECA+ P +C +G C N G Y C C PG + GP +T
Sbjct: 414 GEVGADCPQGYKRL-NSTHCQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRT 471
Query: 507 -CV 508
C+
Sbjct: 472 QCI 474
Score = 49.6 bits (113), Expect = 5e-05
Identities = 24/53 (45%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
G CP GY + HC+DI+EC P VC H C N GSY C CP G+
Sbjct: 414 GEVGADCPQGYK-RLNSTHCQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGH 464
Score = 47.2 bits (107), Expect = 2e-04
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDEC----ERDTHTCQQICSNTEGSYECSCEDG 850
C G C C G++LD A C D+DEC +R + C NT GS+ C C+ G
Sbjct: 1307 CVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAG 1366
Query: 851 YEK 853
+ +
Sbjct: 1367 FAR 1369
Score = 46.8 bits (106), Expect = 3e-04
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 9/84 (10%)
Query: 23 CCCSVGHAWG-APCEACPP-------RGSPAHTALCGEKPGEYINPVTNETKPIDECDIM 74
CC S+G AWG + C CP + P + + P Y + + I+EC M
Sbjct: 382 CCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINEC-AM 440
Query: 75 PQLCKPGTCHDTPTGFQCGCDHGY 98
P +C+ G C + P ++C C G+
Sbjct: 441 PGVCRHGDCLNNPGSYRCVCPPGH 464
Score = 44.0 bits (99), Expect = 0.002
Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 2/74 (2%)
Query: 488 RGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVH 547
RG C G+ + C D++ECA C N GS+RC CP G+++
Sbjct: 413 RGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQ 472
Query: 548 CRDIDECVQEPRVC 561
C I + +E +C
Sbjct: 473 C--IADKPEEKSLC 484
Score = 43.6 bits (98), Expect = 0.003
Identities = 32/89 (35%), Positives = 39/89 (43%), Gaps = 11/89 (12%)
Query: 742 LDVFADVDECAAIPGLC--APGRFRCVCGPG--YRPAGEVCA-----DVDECAVRPPPCD 792
+DV +DE G+C G +RC C P Y PA C DVDEC P C
Sbjct: 1114 VDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQ-DPAACR 1172
Query: 793 Q-LCHNTDGSYDCLCRTGYELDEDGANCR 820
C N GSY C CR + G +C+
Sbjct: 1173 PGRCVNLPGSYRCECRPPWVPGPSGRDCQ 1201
Score = 39.1 bits (87), Expect = 0.066
Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 3/55 (5%)
Query: 767 CGPGYRPAGEV-CADVDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDEDGANC 819
C GY+ C D++ECA+ P C C N GSY C+C G+ L C
Sbjct: 420 CPQGYKRLNSTHCQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC 473
Score = 34.3 bits (75), Expect = 1.9
Identities = 28/102 (27%), Positives = 39/102 (38%), Gaps = 20/102 (19%)
Query: 678 GHVTKAQCCCTLGAAWG-SECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXX 736
G + CC ++G AWG S+C CP +L P
Sbjct: 375 GLTKQEDCCGSIGTAWGQSKCHKCP------QLQYTGVQKPGPVRGEVGADCPQGYKRLN 428
Query: 737 XXXXXLDVFADVDECAAIPGLCA-------PGRFRCVCGPGY 771
D++ECA +PG+C PG +RCVC PG+
Sbjct: 429 STHCQ-----DINECA-MPGVCRHGDCLNNPGSYRCVCPPGH 464
Score = 33.9 bits (74), Expect = 2.5
Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C GY+ + +C+D++EC C N GSY C C G+
Sbjct: 420 CPQGYKR-LNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGH 464
Score = 33.9 bits (74), Expect = 2.5
Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 14/84 (16%)
Query: 782 DECAVRPPPCDQLCHNTDGSYDCLCRTG--YELDEDGANC-----RDVDECER-DTHTCQ 833
D C + P P + + LC G Y D + N RD+DEC + C+
Sbjct: 1031 DHCEIYPCPV-----YSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICK 1085
Query: 834 Q-ICSNTEGSYECSCEDGYEKRGD 856
+ C NT+ YEC C+ G+ G+
Sbjct: 1086 EGKCVNTQPGYECYCKQGFYYDGN 1109
>AK131282-1|BAD18457.1| 872|Homo sapiens protein ( Homo sapiens
cDNA FLJ16233 fis, clone FEBRA2028256, moderately
similar to FIBRILLIN 2 PRECURSOR. ).
Length = 872
Score = 385 bits (948), Expect = e-106
Identities = 200/518 (38%), Positives = 263/518 (50%), Gaps = 28/518 (5%)
Query: 142 RLTPSLDEC-EDVDECGDQR-ICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSR 197
R P D+ EDV+EC + +C +G C NT GS+RCEC GY+L C D DECS
Sbjct: 179 RAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV 238
Query: 198 PRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRC 257
P C GTC N+ G + C C DGF+ G C D++EC ++C RC NT GS+ C
Sbjct: 239 GHP-CGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAF-RCHNTEGSYLC 296
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV---GRR 314
C GYTL DG CRDVDEC + C G C N G + C C G + + G
Sbjct: 297 TCPAGYTLREDGAMCRDVDECADGQQDCHARGM-ECKNLIGTFACVCPPGMRPLPGSGEG 355
Query: 315 CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC 374
C D +EC P +C G C N G + C+C G++ T C D R+ C+ E C
Sbjct: 356 CTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMC 415
Query: 375 HRARPLQLA--RPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRV 432
A R ECCC G WG CE CP P ++ + ++C G G +D+DECR+
Sbjct: 416 RSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRM 475
Query: 433 RPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYE 492
+C G C+N+ GSFRC C GY +C+D DEC+ P+ C C NT+G +
Sbjct: 476 LAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGSFL 534
Query: 493 CQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI 551
C C G+ D +TC D+DEC + +C F C NT G+F C CP G+ C D+
Sbjct: 535 CSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQA--CFDV 592
Query: 552 DECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVC 611
+EC P C H C+N +G Y C CP+G+ T Q ++ C D NEC C C
Sbjct: 593 NEC-DGPHRCQHGCQNQLGGYRCSCPQGF--TQHSQWAQ--CVDENECALSPPTCGSASC 647
Query: 612 INTDGSFLCDCDAGFE------PSEDGTDCIDRRTGTC 643
NT G F C C +GF+ +D +C RR G C
Sbjct: 648 RNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRR-GPC 684
Score = 378 bits (929), Expect = e-104
Identities = 187/446 (41%), Positives = 233/446 (52%), Gaps = 45/446 (10%)
Query: 419 GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRI 478
G + +D++EC P VC G CVNTDGSFRCECP GY L G++CVD DEC++
Sbjct: 183 GPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HP 241
Query: 479 CGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYG 538
CG GTC+N GG+EC C+ GF G TC D+DEC+ C FRCHNT GS+ CTCP G
Sbjct: 242 CGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAG 301
Query: 539 YAVAADGVHCRDIDECVQEPRVCPHA----CENVVGSYICKCPEGYRRTSAPQDSENACE 594
Y + DG CRD+DEC + C HA C+N++G++ C CP G R P E C
Sbjct: 302 YTLREDGAMCRDVDECADGQQDC-HARGMECKNLIGTFACVCPPGMR--PLPGSGE-GCT 357
Query: 595 DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEP 654
D NEC Q DLC G C+NT GSF CDCD GF+PS T+C D R G C+ ++ C
Sbjct: 358 DDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCR- 416
Query: 655 EXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLCTA 714
VT+A+CCC G WG CELCP PG+ A LC
Sbjct: 417 -----------------SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCP- 458
Query: 715 VNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCAPGRFRCVCGPGYRP- 773
+ A + CA + + G FRC C GY P
Sbjct: 459 -------------HGSGYTAEGRDVDECRMLAHL--CAHGECINSLGSFRCHCQAGYTPD 503
Query: 774 -AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC 832
C D+DEC+ P PC LC NT GS+ C C GY L+EDG C+D+DEC H C
Sbjct: 504 ATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNC 563
Query: 833 QQICSNTEGSYECSCEDGYEKRGDAC 858
Q +C NT G++ C C G+ + AC
Sbjct: 564 QFLCVNTVGAFTCRCPPGFTQHHQAC 589
Score = 301 bits (739), Expect = 7e-81
Identities = 206/579 (35%), Positives = 262/579 (45%), Gaps = 80/579 (13%)
Query: 34 PCEACPPRGSPAHT---ALCGEKPGEYIN----PVTNETKP-IDECDIMPQLCKPGTCHD 85
P + PPR + A GE P ++ P ++++ ++EC P +C G C +
Sbjct: 149 PKLSTPPRPAAAAVRGLGRAGETPANCVSRRAVPGPDDSREDVNECAENPGVCTNGVCVN 208
Query: 86 TPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTP 145
T F+C C GY D T C D DECS G PC G C N+ G FEC C G+ P
Sbjct: 209 TDGSFRCECPFGYSLDFTGINCVDTDECSVGH-PC-GQGTCTNVIGGFECACADGFE--P 264
Query: 146 SL-DECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVC 202
L CED+DEC + C NT GSY C C GYTLRE+ +CRDVDEC+ + C
Sbjct: 265 GLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDC 324
Query: 203 --RNGTCENLPGAYLCHCDDGFK--AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCE 258
R C+NL G + C C G + G C D NEC +C NGRC NT GSFRC+
Sbjct: 325 HARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCD 384
Query: 259 CAPGYTLTADGRNCRDVDE----CDELPHPC-------------------GRDGNPSC-- 293
C G+ + C D+ + + L C GR P C
Sbjct: 385 CDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCEL 444
Query: 294 --TNTNGGYE--CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWR 349
Y C G+G+ GR D DEC+ L ++CA GEC N G + C C AG+
Sbjct: 445 CPLPGTSAYRKLCPHGSGYTAEGR---DVDECRMLAHLCAHGECINSLGSFRCHCQAGYT 501
Query: 350 FDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAW---GRYCERCPAPD 406
D TA C+D + + C + L C C G GR C+
Sbjct: 502 PDATATTCLDMDECSQVPKPCTFLCKNTKGSFL----CSCPRGYLLEEDGRTCKDLDECT 557
Query: 407 SAEF--MRICQGGMGR------PNLTQ------DLDECRVRPDVCVGGRCVNTDGSFRCE 452
S + +C +G P TQ D++EC P C G C N G +RC
Sbjct: 558 SRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDVNECD-GPHRCQHG-CQNQLGGYRCS 615
Query: 453 CPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT---CVD 509
CP G+ CVD +ECAL P CG+ +C NT GG+ C C GF DQ C D
Sbjct: 616 CPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDF--DQALGGCQD 673
Query: 510 VDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC 548
VDECA R C++ C NT G F C CP GY A G HC
Sbjct: 674 VDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG-HC 711
Score = 237 bits (579), Expect = 2e-61
Identities = 169/479 (35%), Positives = 210/479 (43%), Gaps = 77/479 (16%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC--RGMAQ 125
IDEC + P LC CH+T + C C GY +CRDVDEC+ G+ C RGM +
Sbjct: 273 IDECSLNPLLCA-FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGM-E 330
Query: 126 CVNLPGAFECRCPPGYRLTPSLDE-CEDVDECGDQR-ICDHGDCRNTIGSYRCECKPGY- 182
C NL G F C CPPG R P E C D +EC Q +C +G C NT GS+RC+C G+
Sbjct: 331 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 390
Query: 183 ---TLRE---------------NVCRDVDECS----RPRPVCRNGT-----CE--NLPG- 212
TL E +CR + S R C G CE LPG
Sbjct: 391 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGT 450
Query: 213 -AYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRN 271
AY C G +G + DV+ECR +C +G C N++GSFRC C GYT A
Sbjct: 451 SAYRKLCPHG--SGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATT 508
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCA 329
C D+DEC ++P PC C NT G + CSC G+ L GR C D DEC + C
Sbjct: 509 CLDMDECSQVPKPC----TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQ 564
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C N G + C CP G F + C D + C RC QL C C
Sbjct: 565 F-LCVNTVGAFTCRCPPG--FTQHHQACFDVNE--CDGPH---RCQHGCQNQLGGYRCSC 616
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
+G +C D +EC + P C C NT G F
Sbjct: 617 PQGFTQHSQWAQCV----------------------DENECALSPPTCGSASCRNTLGGF 654
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV 508
RC CP G+ C D DECA C +C+NT GG+ C C G+ + CV
Sbjct: 655 RCVCPSGFDFDQALGGCQDVDECAGRRGPCSY-SCANTPGGFLCGCPQGYFRAGQGHCV 712
Score = 232 bits (567), Expect = 5e-60
Identities = 117/300 (39%), Positives = 151/300 (50%), Gaps = 15/300 (5%)
Query: 19 TKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLC 78
T+ CCC G WG CE CP G+ A+ LC G T E + +DEC ++ LC
Sbjct: 426 TRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSG-----YTAEGRDVDECRMLAHLC 480
Query: 79 KPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCP 138
G C ++ F+C C GY D T+ C D+DECS PC + C N G+F C CP
Sbjct: 481 AHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFL--CKNTKGSFLCSCP 538
Query: 139 PGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRP 198
GY L C+D+DEC ++ C NT+G++ C C PG+T C DV+EC P
Sbjct: 539 RGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDVNECDGP 598
Query: 199 RPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCRNGRCRNTVGSFRC 257
C++G C+N G Y C C GF CVD NEC C + CRNT+G FRC
Sbjct: 599 HR-CQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRC 656
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR-RCV 316
C G+ C+DVDEC PC + SC NT GG+ C C G+ G+ CV
Sbjct: 657 VCPSGFDFDQALGGCQDVDECAGRRGPC----SYSCANTPGGFLCGCPQGYFRAGQGHCV 712
Score = 169 bits (410), Expect = 5e-41
Identities = 88/218 (40%), Positives = 109/218 (50%), Gaps = 15/218 (6%)
Query: 414 CQGGMGRPNLTQ----DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
CQ G P+ T D+DEC P C C NT GSF C CP GY+L DG +C D
Sbjct: 496 CQAGY-TPDATATTCLDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDL 553
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAG 529
DEC C C NT G + C+C PGFTQ Q C DV+EC +G C C N G
Sbjct: 554 DECTSRQHNC-QFLCVNTVGAFTCRCPPGFTQH-HQACFDVNEC-DGPHRCQHGCQNQLG 610
Query: 530 SFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQD 588
+RC+CP G+ + C D +EC P C A C N +G + C CP G+ A
Sbjct: 611 GYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQAL-- 668
Query: 589 SENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
C+D++EC + CS C NT G FLC C G+
Sbjct: 669 --GGCQDVDECAGRRGPCSYS-CANTPGGFLCGCPQGY 703
Score = 91.1 bits (216), Expect = 2e-17
Identities = 49/122 (40%), Positives = 59/122 (48%), Gaps = 10/122 (8%)
Query: 747 DVDECAAIPGLCA-------PGRFRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHN 797
DV+ECA PG+C G FRC C GY G C D DEC+V P C N
Sbjct: 190 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTN 249
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA 857
G ++C C G+E C D+DEC + C C NTEGSY C+C GY R D
Sbjct: 250 VIGGFECACADGFEPGLM-MTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDG 308
Query: 858 CV 859
+
Sbjct: 309 AM 310
Score = 89.0 bits (211), Expect = 6e-17
Identities = 39/103 (37%), Positives = 54/103 (52%), Gaps = 4/103 (3%)
Query: 761 GRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDEDGA 817
G +RC C G+ + C D +ECA+ PP C C NT G + C+C +G++ D+
Sbjct: 610 GGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALG 669
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
C+DVDEC C C+NT G + C C GY + G CV
Sbjct: 670 GCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCV 712
Score = 82.2 bits (194), Expect = 7e-15
Identities = 45/105 (42%), Positives = 54/105 (51%), Gaps = 5/105 (4%)
Query: 752 AAIPGLCAPGRF--RCVCGPGYRPAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRT 808
AA+ GL G CV + DV+ECA P C +C NTDGS+ C C
Sbjct: 160 AAVRGLGRAGETPANCVSRRAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPF 219
Query: 809 GYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE 852
GY LD G NC D DEC H C Q C+N G +EC+C DG+E
Sbjct: 220 GYSLDFTGINCVDTDECSVG-HPCGQGTCTNVIGGFECACADGFE 263
Score = 74.9 bits (176), Expect = 1e-12
Identities = 39/113 (34%), Positives = 49/113 (43%), Gaps = 8/113 (7%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDG 800
D+DEC + C G F C C PG+ + C DV+EC P C C N G
Sbjct: 552 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDVNECD-GPHRCQHGCQNQLG 610
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYE 852
Y C C G+ A C D +EC TC C NT G + C C G++
Sbjct: 611 GYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFD 663
>BC008761-1|AAH08761.2| 743|Homo sapiens LTBP3 protein protein.
Length = 743
Score = 384 bits (944), Expect = e-106
Identities = 232/639 (36%), Positives = 308/639 (48%), Gaps = 60/639 (9%)
Query: 38 CPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGT--CHDTPTGFQCGCD 95
C P G P ++ C PG +P ++EC+ P C PG C +T + C C+
Sbjct: 77 CVP-GPPDYSCHCN--PGYRSHPQHRYCVDVNECEAEP--CGPGRGICMNTGGSYNCHCN 131
Query: 96 HGYE-HDNTS-HLCRDVDECSWGRPP-CRGMAQCVNLPGAFECRCPPGYRLTPSLDE-CE 151
GY H C D++EC+ +P C C+N PG ++C C PGYRL S CE
Sbjct: 132 RGYRLHVGAGGRSCVDLNECA--KPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCE 189
Query: 152 DVDECGDQRICDHGDCRNTIGSYRC-ECKPGYTLREN-VCRDVDECSRPRPVCRNGTCEN 209
D+DEC D C G C N GS++C C+PGY + CRDV+EC+ P C G CEN
Sbjct: 190 DIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSP-CSPGWCEN 248
Query: 210 LPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTAD 268
LPG++ C C G+ P+ C+DV+EC E G VC NG C NT GSF+C+C GY L+ D
Sbjct: 249 LPGSFRCTCAQGYAPAPDGRSCLDVDEC-EAGDVCDNGICSNTPGSFQCQCLSGYHLSRD 307
Query: 269 GRNCRDVDECDELPHPC-GRDGNPSCTNTNGGYECSCGAGWKLV-GRRCVDRDECKELPY 326
+C D+DECD P C G D C NTNG Y C C G +LV GR+C D DEC + P
Sbjct: 308 RSHCEDIDECD-FPAACIGGD----CINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPS 362
Query: 327 VC-AGGECRNFNGGYVCECPAGWRFDKTAAVCVD----ERKELCYDEW-EAGRCHRARPL 380
+C G C+N G YVC C G+ + C + K+ CY + + C
Sbjct: 363 LCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLAT 422
Query: 381 QLARPECCCSEGAAWGRYCE--RCPAPDSAEFMRICQGGMGRP---NLT-------QDLD 428
+ + ECCCS GA WG +CE CP SAEF +C G G N+ +D+D
Sbjct: 423 NVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDID 482
Query: 429 ECRV-RPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNT 487
EC + ++C G+CVNT + C C G+ + L CVD DEC LD C NG C NT
Sbjct: 483 ECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDEC-LDESNCRNGVCENT 541
Query: 488 RGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCTFRCHNTAGSFRCTCPY-GYAVAADG 545
RGGY C C+P P Q C+ +E C P G A+ D
Sbjct: 542 RGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDD 601
Query: 546 VHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENAC-------EDINE 598
CR + R CP GS+ CP +++ D+ ED +E
Sbjct: 602 CCCRQGRGWGAQCRPCP---PRGAGSH---CPTSQSESNSFWDTSPLLLGKPPRDEDSSE 655
Query: 599 CEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
+ E C G C+ G +C+C GF+ C+D
Sbjct: 656 EDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVD 694
Score = 284 bits (697), Expect = 8e-76
Identities = 182/498 (36%), Positives = 222/498 (44%), Gaps = 42/498 (8%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC + +C G C P + C C+ GY C DV+EC P G C+N
Sbjct: 63 DECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECE-AEPCGPGRGICMN 121
Query: 129 LPGAFECRCPPGYRLTPSLD--ECEDVDECGDQRIC-DHGDCRNTIGSYRCECKPGYTL- 184
G++ C C GYRL C D++EC +C D G C N G Y+C C PGY L
Sbjct: 122 TGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLK 181
Query: 185 --RENVCRDVDECSRPRPVCRNGTCENLPGAYLC-HCDDGFKAGPNNDCVDVNECREGGM 241
R VC D+DEC P C +G CEN PG++ C C G+++ C DVNEC EG
Sbjct: 182 ASRPPVCEDIDECRDPSS-CPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGS- 239
Query: 242 VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
C G C N GSFRC CA GY DGR+C DVDEC E C N C+NT G ++
Sbjct: 240 PCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDEC-EAGDVC---DNGICSNTPGSFQ 295
Query: 302 CSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD 359
C C +G+ L R C D DEC + P C GG+C N NG Y C CP G R C D
Sbjct: 296 CQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGDCINTNGSYRCLCPQGHRL-VGGRKCQD 353
Query: 360 ERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQ---- 415
+ C + H A C C EG + C + + C
Sbjct: 354 --IDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFD 411
Query: 416 -----GGMGRPNLTQDLDECRVRP---DVCVGGRC-VNTDGSFRCECPDGYVLAPD---- 462
+ N+TQ C + D C C V + F CPDG D
Sbjct: 412 DTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIV 471
Query: 463 --GLSC-VDADECAL-DPRICGNGTCSNTRGGYECQCSPGF-TQGPDQTCVDVDECAEGR 517
G+ D DEC L IC G C NT+ GYEC C GF G CVDVDEC +
Sbjct: 472 NYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDES 531
Query: 518 ASCTFRCHNTAGSFRCTC 535
C NT G +RC C
Sbjct: 532 NCRNGVCENTRGGYRCAC 549
Score = 262 bits (643), Expect = 3e-69
Identities = 219/743 (29%), Positives = 295/743 (39%), Gaps = 98/743 (13%)
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICD--HGD 166
+ DEC + C G +CV P + C C PGYR P C DV+EC + C G
Sbjct: 61 ETDECRLNQNIC-GHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNEC-EAEPCGPGRGI 118
Query: 167 CRNTIGSYRCECKPGYTLRENV----CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
C NT GSY C C GY L C D++EC++P G C N PG Y C+C G+
Sbjct: 119 CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGY 178
Query: 223 --KAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRC-ECAPGYTLTADGRNCRDVDECD 279
KA C D++ECR+ C +G+C N GSF+C C PGY G CRDV+EC
Sbjct: 179 RLKASRPPVCEDIDECRDPSS-CPDGKCENKPGSFKCIACQPGYRSQGGGA-CRDVNECA 236
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFN 337
E PC C N G + C+C G+ GR C+D DEC E VC G C N
Sbjct: 237 E-GSPCSPGW---CENLPGSFRCTCAQGYAPAPDGRSCLDVDEC-EAGDVCDNGICSNTP 291
Query: 338 GGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGR 397
G + C+C +G+ + + C D DE + P +C + G+
Sbjct: 292 GSFQCQCLSGYHLSRDRSHCED------IDECDF-------PAACIGGDCINTNGSY--- 335
Query: 398 YCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDG 456
RC P + GG QD+DEC P +C+ G C N GS+ C C +G
Sbjct: 336 ---RCLCPQGHRLV----GG----RKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEG 384
Query: 457 YVLAPDGLSCVDAD------ECAL---DPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC 507
+ D C + + EC L D C + +N EC CS G G C
Sbjct: 385 FTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQ-QECCCSLGAGWGDH--C 441
Query: 508 VDVDEC-AEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ-EPRVCPHA- 564
++ C A C + G + Y + A RDIDEC+ +C
Sbjct: 442 -EIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAH----RDIDECMLFGSEICKEGK 496
Query: 565 CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDA 624
C N Y C C +G+ + C D++EC ++ + C GVC NT G + C C
Sbjct: 497 CVNTQPGYECYCKQGFYYDGNLLE----CVDVDECLDESN-CRNGVCENTRGGYRCACTP 551
Query: 625 GFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQ 684
E S C+ S PE +T
Sbjct: 552 PAEYSPAQRQCL---------SPEEMERAPERRDVCWSQRGEDGMCAGPLAGPA-LTFDD 601
Query: 685 CCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDV 744
CCC G WG++C CP G+ + C T
Sbjct: 602 CCCRQGRGWGAQCRPCPPRGAGSH---CP----TSQSESNSFWDTSPLLLGKPPRDEDSS 654
Query: 745 FADVDECAAIPGLCAP--GRFRCVCGPGYR--PAGEVCADVDECAV---RPPPC-DQLCH 796
D DEC + G C P G C C G++ + C D+DEC R C + C
Sbjct: 655 EEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCV 714
Query: 797 NTDGSYDCLCRTGYELDEDGANC 819
NT GS+ C+C+ G+ C
Sbjct: 715 NTSGSFRCVCKAGFARSRPHGAC 737
Score = 241 bits (591), Expect = 6e-63
Identities = 176/585 (30%), Positives = 236/585 (40%), Gaps = 79/585 (13%)
Query: 274 DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGG 331
+ DEC + CG C Y C C G++ R CVD +EC+ P G
Sbjct: 61 ETDECRLNQNICGHG---ECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRG 117
Query: 332 ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSE 391
C N G Y C C G+R A C D E + H C +
Sbjct: 118 ICMNTGGSYNCHCNRGYRLHVGAG------GRSCVDLNECAKPH------------LCGD 159
Query: 392 GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRC 451
G +C P + RP + +D+DECR P C G+C N GSF+C
Sbjct: 160 GG----FCINFPGHYKCNCYPGYRLKASRPPVCEDIDECR-DPSSCPDGKCENKPGSFKC 214
Query: 452 -ECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVD 509
C GY + G +C D +ECA + C G C N G + C C+ G+ PD ++C+D
Sbjct: 215 IACQPGY-RSQGGGACRDVNECA-EGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLD 272
Query: 510 VDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENV 568
VDEC G C NT GSF+C C GY ++ D HC DIDEC P C C N
Sbjct: 273 VDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGDCINT 331
Query: 569 VGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFE 627
GSY C CP+G+R + C+DI+EC + LC G C N GS++C CD GF
Sbjct: 332 NGSYRCLCPQGHRLVGGRK-----CQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFT 386
Query: 628 PSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCC 687
P++D C + +P +VT+ +CCC
Sbjct: 387 PTQDQHGCEEVE-------------QPHHKKECYLNFDDTVFCDSVLAT--NVTQQECCC 431
Query: 688 TLGAAWGSECELCPAPG-SPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFA 746
+LGA WG CE+ P P S A +L P +
Sbjct: 432 SLGAGWGDHCEIYPCPVYSSAEFH-----SLCPDGKGYTQDNNIVNYG-------IPAHR 479
Query: 747 DVDECAAIPG-LCAPGR-------FRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCH 796
D+DEC +C G+ + C C G+ G + C DVDEC + +C
Sbjct: 480 DIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCE 539
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEG 841
NT G Y C C E C +E ER + +C + G
Sbjct: 540 NTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPER-RDVCWSQRG 583
Score = 219 bits (536), Expect = 3e-56
Identities = 160/520 (30%), Positives = 219/520 (42%), Gaps = 72/520 (13%)
Query: 42 GSPAHTALCGEKPGEYINPVTNETKP---------IDECDIMPQLCKPGTCHDTPTGFQC 92
GSP C PG + P +DEC+ +C G C +TP FQC
Sbjct: 238 GSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEA-GDVCDNGICSNTPGSFQC 296
Query: 93 GCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECED 152
C GY C D+DEC + C G C+N G++ C CP G+RL +C+D
Sbjct: 297 QCLSGYHLSRDRSHCEDIDECDFPAA-CIG-GDCINTNGSYRCLCPQGHRLVGGR-KCQD 353
Query: 153 VDECG-DQRIC-DHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGT-- 206
+DEC D +C HG C+N GSY C C G+T ++ C +V++ + N
Sbjct: 354 IDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDT 413
Query: 207 --CENLPGAYLCH--CDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPG 262
C+++ + C AG + C ++ C + C + G +
Sbjct: 414 VFCDSVLATNVTQQECCCSLGAGWGDHC-EIYPCPVYSSAEFHSLCPDGKGYTQDNNIVN 472
Query: 263 YTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR--RCVDRDE 320
Y + A RD+DEC ++G C NT GYEC C G+ G CVD DE
Sbjct: 473 YGIPAH----RDIDECMLFGSEICKEGK--CVNTQPGYECYCKQGFYYDGNLLECVDVDE 526
Query: 321 CKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD--------ERKELCYDE-WEA 371
C + C G C N GGY C C + C+ ER+++C+ + E
Sbjct: 527 CLDESN-CRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGED 585
Query: 372 GRCHRARPLQ---LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG----------- 417
G C A PL L +CCC +G WG C CP + Q
Sbjct: 586 GMC--AGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLL 643
Query: 418 MGRP-----NLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC 472
+G+P + +D DECR CV GRCV G CECP G+ L CVD DEC
Sbjct: 644 LGKPPRDEDSSEEDSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDEC 698
Query: 473 -ALDPR--ICGNGTCSNTRGGYECQCSPGFTQG-PDQTCV 508
L+ R +C + C NT G + C C GF + P CV
Sbjct: 699 RELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACV 738
Score = 162 bits (393), Expect = 6e-39
Identities = 86/224 (38%), Positives = 110/224 (49%), Gaps = 14/224 (6%)
Query: 421 PNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG 480
P + DECR+ ++C G CV + C C GY P CVD +EC +P G
Sbjct: 56 PTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPG 115
Query: 481 NGTCSNTRGGYECQCSPGF---TQGPDQTCVDVDECAEGR-ASCTFRCHNTAGSFRCTCP 536
G C NT G Y C C+ G+ ++CVD++ECA+ C N G ++C C
Sbjct: 116 RGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCY 175
Query: 537 YGYAVAADGVH-CRDIDECVQEPRVCPHA-CENVVGSYIC-KCPEGYRRTSAPQDSENAC 593
GY + A C DIDEC ++P CP CEN GS+ C C GYR AC
Sbjct: 176 PGYRLKASRPPVCEDIDEC-RDPSSCPDGKCENKPGSFKCIACQPGYR-----SQGGGAC 229
Query: 594 EDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
D+NEC E CS G C N GSF C C G+ P+ DG C+D
Sbjct: 230 RDVNECAEGSP-CSPGWCENLPGSFRCTCAQGYAPAPDGRSCLD 272
Score = 124 bits (298), Expect = 2e-27
Identities = 93/319 (29%), Positives = 133/319 (41%), Gaps = 26/319 (8%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCE--ACPPRGSPAHTALCGEKPG-EYINPVTNETK 66
C + T+ CCCS+G WG CE CP S +LC + G N + N
Sbjct: 416 CDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGI 475
Query: 67 P----IDECDIM-PQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
P IDEC + ++CK G C +T G++C C G+ +D C DVDEC CR
Sbjct: 476 PAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDEC-LDESNCR 534
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDEC---EDVDECGDQR-IC--DHGDCRNTIGSYR 175
C N G + C C P +P+ +C E+++ ++R +C G+ G
Sbjct: 535 N-GVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPL- 592
Query: 176 CECKPGYTLRENVCRDVDEC-SRPRPVCRNGTCENLPGAYLCHCDDGFKAGP---NNDCV 231
P T + CR ++ RP G + P + + + P
Sbjct: 593 --AGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQ-SESNSFWDTSPLLLGKPPR 649
Query: 232 DVNECREGGMVCR--NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDG 289
D + E CR +GRC G CEC G+ L A C D+DEC EL
Sbjct: 650 DEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCK 709
Query: 290 NPSCTNTNGGYECSCGAGW 308
+ C NT+G + C C AG+
Sbjct: 710 SERCVNTSGSFRCVCKAGF 728
Score = 116 bits (278), Expect = 5e-25
Identities = 89/276 (32%), Positives = 123/276 (44%), Gaps = 33/276 (11%)
Query: 108 RDVDECS-WGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD 166
RD+DEC +G C+ +CVN +EC C G+ +L EC DVDEC D+ C +G
Sbjct: 479 RDIDECMLFGSEICKE-GKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGV 537
Query: 167 CRNTIGSYRCECKPG--YTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA 224
C NT G YRC C P Y+ + C +E R R C + G +DG A
Sbjct: 538 CENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPE--RRDVCWSQRG------EDGMCA 589
Query: 225 GP-NNDCVDVNEC--REG---GMVCRNGRCRNTVGSFRCECAPG----YTLTAD---GRN 271
GP + ++C R+G G CR C C + + T+ G+
Sbjct: 590 GPLAGPALTFDDCCCRQGRGWGAQCRP--CPPRGAGSHCPTSQSESNSFWDTSPLLLGKP 647
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPY--- 326
RD D +E C R + C GG C C G++L R CVD DEC+EL
Sbjct: 648 PRDEDSSEEDSDEC-RCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGL 706
Query: 327 VCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
+C C N +G + C C AG+ + CV +R+
Sbjct: 707 LCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRR 742
Score = 104 bits (250), Expect = 1e-21
Identities = 51/117 (43%), Positives = 61/117 (52%), Gaps = 8/117 (6%)
Query: 747 DVDECA----AIPGLCA--PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNT 798
DV+ECA PG C PG FRC C GY PA G C DVDEC + +C NT
Sbjct: 231 DVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNT 290
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
GS+ C C +GY L D ++C D+DEC+ C NT GSY C C G+ G
Sbjct: 291 PGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVG 347
Score = 102 bits (244), Expect = 6e-21
Identities = 54/121 (44%), Positives = 64/121 (52%), Gaps = 8/121 (6%)
Query: 744 VFADVDEC---AAIP-GLCA--PGRFRCV-CGPGYRP-AGEVCADVDECAVRPPPCDQLC 795
V D+DEC ++ P G C PG F+C+ C PGYR G C DV+ECA P C
Sbjct: 187 VCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWC 246
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
N GS+ C C GY DG +C DVDECE ICSNT GS++C C GY
Sbjct: 247 ENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSR 306
Query: 856 D 856
D
Sbjct: 307 D 307
Score = 85.4 bits (202), Expect = 8e-16
Identities = 48/123 (39%), Positives = 61/123 (49%), Gaps = 16/123 (13%)
Query: 747 DVDECAAIPGLCA--------PGRFRCVCGPGYRPAGE---VCADVDECAVRPPPC-DQL 794
D++ECA P LC PG ++C C PGYR VC D+DEC P C D
Sbjct: 147 DLNECAK-PHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECR-DPSSCPDGK 204
Query: 795 CHNTDGSYDCL-CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C N GS+ C+ C+ GY + G CRDV+EC + C N GS+ C+C GY
Sbjct: 205 CENKPGSFKCIACQPGYR-SQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAP 263
Query: 854 RGD 856
D
Sbjct: 264 APD 266
Score = 83.4 bits (197), Expect = 3e-15
Identities = 44/105 (41%), Positives = 54/105 (51%), Gaps = 10/105 (9%)
Query: 756 GLCAPGR--FRCVCGPGYR--PAGEVCADVDECAVRP-PPCDQLCHNTDGSYDCLCRTGY 810
G C PG + C C PGYR P C DV+EC P P +C NT GSY+C C GY
Sbjct: 75 GECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGY 134
Query: 811 EL--DEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
L G +C D++EC + H C C N G Y+C+C GY
Sbjct: 135 RLHVGAGGRSCVDLNECAK-PHLCGDGGFCINFPGHYKCNCYPGY 178
Score = 82.6 bits (195), Expect = 5e-15
Identities = 49/150 (32%), Positives = 66/150 (44%), Gaps = 11/150 (7%)
Query: 3 WNE--EDQSCAGAVGVPQTKYL-CCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEY-- 57
W++ ED CAG + P + CCC G WGA C CPPRG+ +H + +
Sbjct: 579 WSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWD 638
Query: 58 INPVTNETKPIDEC----DIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDEC 113
+P+ P DE D C G C P G C C G++ D + C D+DEC
Sbjct: 639 TSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDEC 698
Query: 114 SW--GRPPCRGMAQCVNLPGAFECRCPPGY 141
R +CVN G+F C C G+
Sbjct: 699 RELNQRGLLCKSERCVNTSGSFRCVCKAGF 728
Score = 75.4 bits (177), Expect = 8e-13
Identities = 70/232 (30%), Positives = 93/232 (40%), Gaps = 31/232 (13%)
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
D+DEC + C G C NT G +RC C +P C+ +E P C
Sbjct: 523 DVDECLDESN-CRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPE--RRDVCW 579
Query: 486 NTRGGYECQCSPGFTQGPDQTCVDVDECAEGR---ASCTFRCHNTAGSFRCTCPYGYAVA 542
+ RG + C+ G GP T D C +GR A C AGS CP + +
Sbjct: 580 SQRGE-DGMCA-GPLAGPALTFDDCC-CRQGRGWGAQCRPCPPRGAGSH---CPTSQSES 633
Query: 543 AD---------GVHCRDIDECVQEPRVC---PHACENVVGSYICKCPEGYRRTSAPQDSE 590
G RD D ++ C C G +C+CP G++ + S
Sbjct: 634 NSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDA----SR 689
Query: 591 NACEDINECEEQED---LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRR 639
C DI+EC E LC C+NT GSF C C AGF S C+ +R
Sbjct: 690 ARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQR 741
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/130 (34%), Positives = 58/130 (44%), Gaps = 19/130 (14%)
Query: 747 DVDEC----AAIPGLC--APGRFRCVCGPGYR-PAGEVCADVDECAVRPPPC--DQLCHN 797
D+DEC A I G C G +RC+C G+R G C D+DEC+ P C C N
Sbjct: 313 DIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKN 372
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVD------ECE---RDTHTCQQICSNTEGSYECSCE 848
GSY C+C G+ +D C +V+ EC DT C + + EC C
Sbjct: 373 LQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCS 432
Query: 849 DGYEKRGDAC 858
G GD C
Sbjct: 433 LG-AGWGDHC 441
Score = 60.5 bits (140), Expect = 2e-08
Identities = 26/70 (37%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 780 DVDECAVRPPP-CDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICS 837
D+DEC + C + C NT Y+C C+ G+ D + C DVDEC +++ +C
Sbjct: 480 DIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCE 539
Query: 838 NTEGSYECSC 847
NT G Y C+C
Sbjct: 540 NTRGGYRCAC 549
Score = 47.2 bits (107), Expect = 2e-04
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDEC----ERDTHTCQQICSNTEGSYECSCEDG 850
C G C C G++LD A C D+DEC +R + C NT GS+ C C+ G
Sbjct: 668 CVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAG 727
Query: 851 YEK 853
+ +
Sbjct: 728 FAR 730
Score = 33.9 bits (74), Expect = 2.5
Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 14/84 (16%)
Query: 782 DECAVRPPPCDQLCHNTDGSYDCLCRTG--YELDEDGANC-----RDVDECER-DTHTCQ 833
D C + P P + + LC G Y D + N RD+DEC + C+
Sbjct: 439 DHCEIYPCPV-----YSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICK 493
Query: 834 Q-ICSNTEGSYECSCEDGYEKRGD 856
+ C NT+ YEC C+ G+ G+
Sbjct: 494 EGKCVNTQPGYECYCKQGFYYDGN 517
Score = 33.1 bits (72), Expect = 4.3
Identities = 12/54 (22%), Positives = 24/54 (44%)
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
SA + + + +EC +++C G C+ + C C+ G+ C+D
Sbjct: 50 SAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVD 103
>AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming growth
factor beta binding protein 3 protein.
Length = 1256
Score = 384 bits (944), Expect = e-106
Identities = 232/639 (36%), Positives = 308/639 (48%), Gaps = 60/639 (9%)
Query: 38 CPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGT--CHDTPTGFQCGCD 95
C P G P ++ C PG +P ++EC+ P C PG C +T + C C+
Sbjct: 590 CVP-GPPDYSCHCN--PGYRSHPQHRYCVDVNECEAEP--CGPGRGICMNTGGSYNCHCN 644
Query: 96 HGYE-HDNTS-HLCRDVDECSWGRPP-CRGMAQCVNLPGAFECRCPPGYRLTPSLDE-CE 151
GY H C D++EC+ +P C C+N PG ++C C PGYRL S CE
Sbjct: 645 RGYRLHVGAGGRSCVDLNECA--KPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCE 702
Query: 152 DVDECGDQRICDHGDCRNTIGSYRC-ECKPGYTLREN-VCRDVDECSRPRPVCRNGTCEN 209
D+DEC D C G C N GS++C C+PGY + CRDV+EC+ P C G CEN
Sbjct: 703 DIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSP-CSPGWCEN 761
Query: 210 LPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTAD 268
LPG++ C C G+ P+ C+DV+EC E G VC NG C NT GSF+C+C GY L+ D
Sbjct: 762 LPGSFRCTCAQGYAPAPDGRSCLDVDEC-EAGDVCDNGICSNTPGSFQCQCLSGYHLSRD 820
Query: 269 GRNCRDVDECDELPHPC-GRDGNPSCTNTNGGYECSCGAGWKLV-GRRCVDRDECKELPY 326
+C D+DECD P C G D C NTNG Y C C G +LV GR+C D DEC + P
Sbjct: 821 RSHCEDIDECD-FPAACIGGD----CINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPS 875
Query: 327 VC-AGGECRNFNGGYVCECPAGWRFDKTAAVCVD----ERKELCYDEW-EAGRCHRARPL 380
+C G C+N G YVC C G+ + C + K+ CY + + C
Sbjct: 876 LCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLAT 935
Query: 381 QLARPECCCSEGAAWGRYCE--RCPAPDSAEFMRICQGGMGRP---NLT-------QDLD 428
+ + ECCCS GA WG +CE CP SAEF +C G G N+ +D+D
Sbjct: 936 NVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDID 995
Query: 429 ECRV-RPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNT 487
EC + ++C G+CVNT + C C G+ + L CVD DEC LD C NG C NT
Sbjct: 996 ECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDEC-LDESNCRNGVCENT 1054
Query: 488 RGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCTFRCHNTAGSFRCTCPY-GYAVAADG 545
RGGY C C+P P Q C+ +E C P G A+ D
Sbjct: 1055 RGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDD 1114
Query: 546 VHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENAC-------EDINE 598
CR + R CP GS+ CP +++ D+ ED +E
Sbjct: 1115 CCCRQGRGWGAQCRPCP---PRGAGSH---CPTSQSESNSFWDTSPLLLGKPPRDEDSSE 1168
Query: 599 CEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
+ E C G C+ G +C+C GF+ C+D
Sbjct: 1169 EDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVD 1207
Score = 284 bits (697), Expect = 8e-76
Identities = 182/498 (36%), Positives = 222/498 (44%), Gaps = 42/498 (8%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC + +C G C P + C C+ GY C DV+EC P G C+N
Sbjct: 576 DECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECE-AEPCGPGRGICMN 634
Query: 129 LPGAFECRCPPGYRLTPSLD--ECEDVDECGDQRIC-DHGDCRNTIGSYRCECKPGYTL- 184
G++ C C GYRL C D++EC +C D G C N G Y+C C PGY L
Sbjct: 635 TGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLK 694
Query: 185 --RENVCRDVDECSRPRPVCRNGTCENLPGAYLC-HCDDGFKAGPNNDCVDVNECREGGM 241
R VC D+DEC P C +G CEN PG++ C C G+++ C DVNEC EG
Sbjct: 695 ASRPPVCEDIDECRDPSS-CPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGS- 752
Query: 242 VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
C G C N GSFRC CA GY DGR+C DVDEC E C N C+NT G ++
Sbjct: 753 PCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDEC-EAGDVC---DNGICSNTPGSFQ 808
Query: 302 CSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD 359
C C +G+ L R C D DEC + P C GG+C N NG Y C CP G R C D
Sbjct: 809 CQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGDCINTNGSYRCLCPQGHRL-VGGRKCQD 866
Query: 360 ERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQ---- 415
+ C + H A C C EG + C + + C
Sbjct: 867 --IDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFD 924
Query: 416 -----GGMGRPNLTQDLDECRVRP---DVCVGGRC-VNTDGSFRCECPDGYVLAPD---- 462
+ N+TQ C + D C C V + F CPDG D
Sbjct: 925 DTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIV 984
Query: 463 --GLSC-VDADECAL-DPRICGNGTCSNTRGGYECQCSPGF-TQGPDQTCVDVDECAEGR 517
G+ D DEC L IC G C NT+ GYEC C GF G CVDVDEC +
Sbjct: 985 NYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDES 1044
Query: 518 ASCTFRCHNTAGSFRCTC 535
C NT G +RC C
Sbjct: 1045 NCRNGVCENTRGGYRCAC 1062
Score = 262 bits (643), Expect = 3e-69
Identities = 219/743 (29%), Positives = 295/743 (39%), Gaps = 98/743 (13%)
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICD--HGD 166
+ DEC + C G +CV P + C C PGYR P C DV+EC + C G
Sbjct: 574 ETDECRLNQNIC-GHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNEC-EAEPCGPGRGI 631
Query: 167 CRNTIGSYRCECKPGYTLRENV----CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
C NT GSY C C GY L C D++EC++P G C N PG Y C+C G+
Sbjct: 632 CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGY 691
Query: 223 --KAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRC-ECAPGYTLTADGRNCRDVDECD 279
KA C D++ECR+ C +G+C N GSF+C C PGY G CRDV+EC
Sbjct: 692 RLKASRPPVCEDIDECRDPSS-CPDGKCENKPGSFKCIACQPGYRSQGGGA-CRDVNECA 749
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFN 337
E PC C N G + C+C G+ GR C+D DEC E VC G C N
Sbjct: 750 E-GSPCSPGW---CENLPGSFRCTCAQGYAPAPDGRSCLDVDEC-EAGDVCDNGICSNTP 804
Query: 338 GGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGR 397
G + C+C +G+ + + C D DE + P +C + G+
Sbjct: 805 GSFQCQCLSGYHLSRDRSHCED------IDECDF-------PAACIGGDCINTNGSY--- 848
Query: 398 YCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDG 456
RC P + GG QD+DEC P +C+ G C N GS+ C C +G
Sbjct: 849 ---RCLCPQGHRLV----GG----RKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEG 897
Query: 457 YVLAPDGLSCVDAD------ECAL---DPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC 507
+ D C + + EC L D C + +N EC CS G G C
Sbjct: 898 FTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQ-QECCCSLGAGWGDH--C 954
Query: 508 VDVDEC-AEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ-EPRVCPHA- 564
++ C A C + G + Y + A RDIDEC+ +C
Sbjct: 955 -EIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAH----RDIDECMLFGSEICKEGK 1009
Query: 565 CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDA 624
C N Y C C +G+ + C D++EC ++ + C GVC NT G + C C
Sbjct: 1010 CVNTQPGYECYCKQGFYYDGNLLE----CVDVDECLDESN-CRNGVCENTRGGYRCACTP 1064
Query: 625 GFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQ 684
E S C+ S PE +T
Sbjct: 1065 PAEYSPAQRQCL---------SPEEMERAPERRDVCWSQRGEDGMCAGPLAGPA-LTFDD 1114
Query: 685 CCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDV 744
CCC G WG++C CP G+ + C T
Sbjct: 1115 CCCRQGRGWGAQCRPCPPRGAGSH---CP----TSQSESNSFWDTSPLLLGKPPRDEDSS 1167
Query: 745 FADVDECAAIPGLCAP--GRFRCVCGPGYR--PAGEVCADVDECAV---RPPPC-DQLCH 796
D DEC + G C P G C C G++ + C D+DEC R C + C
Sbjct: 1168 EEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCV 1227
Query: 797 NTDGSYDCLCRTGYELDEDGANC 819
NT GS+ C+C+ G+ C
Sbjct: 1228 NTSGSFRCVCKAGFARSRPHGAC 1250
Score = 241 bits (591), Expect = 6e-63
Identities = 176/585 (30%), Positives = 236/585 (40%), Gaps = 79/585 (13%)
Query: 274 DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGG 331
+ DEC + CG C Y C C G++ R CVD +EC+ P G
Sbjct: 574 ETDECRLNQNICGHG---ECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRG 630
Query: 332 ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSE 391
C N G Y C C G+R A C D E + H C +
Sbjct: 631 ICMNTGGSYNCHCNRGYRLHVGAG------GRSCVDLNECAKPH------------LCGD 672
Query: 392 GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRC 451
G +C P + RP + +D+DECR P C G+C N GSF+C
Sbjct: 673 GG----FCINFPGHYKCNCYPGYRLKASRPPVCEDIDECR-DPSSCPDGKCENKPGSFKC 727
Query: 452 -ECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVD 509
C GY + G +C D +ECA + C G C N G + C C+ G+ PD ++C+D
Sbjct: 728 IACQPGY-RSQGGGACRDVNECA-EGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLD 785
Query: 510 VDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENV 568
VDEC G C NT GSF+C C GY ++ D HC DIDEC P C C N
Sbjct: 786 VDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGDCINT 844
Query: 569 VGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFE 627
GSY C CP+G+R + C+DI+EC + LC G C N GS++C CD GF
Sbjct: 845 NGSYRCLCPQGHRLVGGRK-----CQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFT 899
Query: 628 PSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCC 687
P++D C + +P +VT+ +CCC
Sbjct: 900 PTQDQHGCEEVE-------------QPHHKKECYLNFDDTVFCDSVLAT--NVTQQECCC 944
Query: 688 TLGAAWGSECELCPAPG-SPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFA 746
+LGA WG CE+ P P S A +L P +
Sbjct: 945 SLGAGWGDHCEIYPCPVYSSAEFH-----SLCPDGKGYTQDNNIVNYG-------IPAHR 992
Query: 747 DVDECAAIPG-LCAPGR-------FRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCH 796
D+DEC +C G+ + C C G+ G + C DVDEC + +C
Sbjct: 993 DIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCE 1052
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEG 841
NT G Y C C E C +E ER + +C + G
Sbjct: 1053 NTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPER-RDVCWSQRG 1096
Score = 235 bits (574), Expect = 6e-61
Identities = 198/671 (29%), Positives = 267/671 (39%), Gaps = 86/671 (12%)
Query: 7 DQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETK 66
+ C + T+ LCCCSVG AWGA C+ CP G+ A +C G +I +++T
Sbjct: 412 EHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHI-LTSHQTL 470
Query: 67 PID-ECDIMPQL-----CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
I E D L KP ++P+ D E T+ + P
Sbjct: 471 TIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPT 530
Query: 121 RGMAQCVNLPGAFECRCPPGYR-----LTPSLDECE-------DVDECG-DQRICDHGDC 167
P PP R L PS E + DEC +Q IC HG+C
Sbjct: 531 ATTTPARPYPELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGEC 590
Query: 168 RNTIGSYRCECKPGYTL--RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK-- 223
Y C C PGY + C DV+EC G C N G+Y CHC+ G++
Sbjct: 591 VPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLH 650
Query: 224 -AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRN-CRDVDECDEL 281
CVD+NEC + + G C N G ++C C PGY L A C D+DEC +
Sbjct: 651 VGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRD- 709
Query: 282 PHPCGRDGNPSCTNTNGGYEC-SCGAGWKLV-GRRCVDRDECKELPYVCAGGECRNFNGG 339
P C DG C N G ++C +C G++ G C D +EC E C+ G C N G
Sbjct: 710 PSSC-PDG--KCENKPGSFKCIACQPGYRSQGGGACRDVNECAE-GSPCSPGWCENLPGS 765
Query: 340 YVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYC 399
+ C C G+ C+D + D + G C P +C C G R
Sbjct: 766 FRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNT-PGSF---QCQCLSGYHLSRDR 821
Query: 400 ERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVL 459
C D +F C G G C+NT+GS+RC CP G+ L
Sbjct: 822 SHCEDIDECDFPAACIG-----------------------GDCINTNGSYRCLCPQGHRL 858
Query: 460 APDGLSCVDADECALDPRIC-GNGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVD------ 511
G C D DEC+ DP +C +G C N +G Y C C GFT DQ C +V+
Sbjct: 859 V-GGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKK 917
Query: 512 EC---AEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENV 568
EC + C C C G A G HC E CP +
Sbjct: 918 ECYLNFDDTVFCDSVLATNVTQQECCCSLG---AGWGDHC--------EIYPCP-VYSSA 965
Query: 569 VGSYICKCPEGYRR-TSAPQDSENACEDINECE-EQEDLCSGGVCINTDGSFLCDCDAGF 626
+C +GY + + A DI+EC ++C G C+NT + C C GF
Sbjct: 966 EFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGF 1025
Query: 627 EPSEDGTDCID 637
+ +C+D
Sbjct: 1026 YYDGNLLECVD 1036
Score = 219 bits (536), Expect = 3e-56
Identities = 160/520 (30%), Positives = 219/520 (42%), Gaps = 72/520 (13%)
Query: 42 GSPAHTALCGEKPGEYINPVTNETKP---------IDECDIMPQLCKPGTCHDTPTGFQC 92
GSP C PG + P +DEC+ +C G C +TP FQC
Sbjct: 751 GSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEA-GDVCDNGICSNTPGSFQC 809
Query: 93 GCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECED 152
C GY C D+DEC + C G C+N G++ C CP G+RL +C+D
Sbjct: 810 QCLSGYHLSRDRSHCEDIDECDFPAA-CIG-GDCINTNGSYRCLCPQGHRLVGGR-KCQD 866
Query: 153 VDECG-DQRIC-DHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGT-- 206
+DEC D +C HG C+N GSY C C G+T ++ C +V++ + N
Sbjct: 867 IDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDT 926
Query: 207 --CENLPGAYLCH--CDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPG 262
C+++ + C AG + C ++ C + C + G +
Sbjct: 927 VFCDSVLATNVTQQECCCSLGAGWGDHC-EIYPCPVYSSAEFHSLCPDGKGYTQDNNIVN 985
Query: 263 YTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR--RCVDRDE 320
Y + A RD+DEC ++G C NT GYEC C G+ G CVD DE
Sbjct: 986 YGIPAH----RDIDECMLFGSEICKEGK--CVNTQPGYECYCKQGFYYDGNLLECVDVDE 1039
Query: 321 CKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD--------ERKELCYDE-WEA 371
C + C G C N GGY C C + C+ ER+++C+ + E
Sbjct: 1040 CLDESN-CRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGED 1098
Query: 372 GRCHRARPLQ---LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG----------- 417
G C A PL L +CCC +G WG C CP + Q
Sbjct: 1099 GMC--AGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLL 1156
Query: 418 MGRP-----NLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC 472
+G+P + +D DECR CV GRCV G CECP G+ L CVD DEC
Sbjct: 1157 LGKPPRDEDSSEEDSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDEC 1211
Query: 473 -ALDPR--ICGNGTCSNTRGGYECQCSPGFTQG-PDQTCV 508
L+ R +C + C NT G + C C GF + P CV
Sbjct: 1212 RELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACV 1251
Score = 124 bits (298), Expect = 2e-27
Identities = 93/319 (29%), Positives = 133/319 (41%), Gaps = 26/319 (8%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCE--ACPPRGSPAHTALCGEKPG-EYINPVTNETK 66
C + T+ CCCS+G WG CE CP S +LC + G N + N
Sbjct: 929 CDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGI 988
Query: 67 P----IDECDIM-PQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
P IDEC + ++CK G C +T G++C C G+ +D C DVDEC CR
Sbjct: 989 PAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDEC-LDESNCR 1047
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDEC---EDVDECGDQR-IC--DHGDCRNTIGSYR 175
C N G + C C P +P+ +C E+++ ++R +C G+ G
Sbjct: 1048 N-GVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPL- 1105
Query: 176 CECKPGYTLRENVCRDVDEC-SRPRPVCRNGTCENLPGAYLCHCDDGFKAGP---NNDCV 231
P T + CR ++ RP G + P + + + P
Sbjct: 1106 --AGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQ-SESNSFWDTSPLLLGKPPR 1162
Query: 232 DVNECREGGMVCR--NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDG 289
D + E CR +GRC G CEC G+ L A C D+DEC EL
Sbjct: 1163 DEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCK 1222
Query: 290 NPSCTNTNGGYECSCGAGW 308
+ C NT+G + C C AG+
Sbjct: 1223 SERCVNTSGSFRCVCKAGF 1241
Score = 116 bits (278), Expect = 5e-25
Identities = 89/276 (32%), Positives = 123/276 (44%), Gaps = 33/276 (11%)
Query: 108 RDVDECS-WGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD 166
RD+DEC +G C+ +CVN +EC C G+ +L EC DVDEC D+ C +G
Sbjct: 992 RDIDECMLFGSEICKE-GKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGV 1050
Query: 167 CRNTIGSYRCECKPG--YTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA 224
C NT G YRC C P Y+ + C +E R R C + G +DG A
Sbjct: 1051 CENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPE--RRDVCWSQRG------EDGMCA 1102
Query: 225 GP-NNDCVDVNEC--REG---GMVCRNGRCRNTVGSFRCECAPG----YTLTAD---GRN 271
GP + ++C R+G G CR C C + + T+ G+
Sbjct: 1103 GPLAGPALTFDDCCCRQGRGWGAQCRP--CPPRGAGSHCPTSQSESNSFWDTSPLLLGKP 1160
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPY--- 326
RD D +E C R + C GG C C G++L R CVD DEC+EL
Sbjct: 1161 PRDEDSSEEDSDEC-RCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGL 1219
Query: 327 VCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
+C C N +G + C C AG+ + CV +R+
Sbjct: 1220 LCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRR 1255
Score = 104 bits (250), Expect = 1e-21
Identities = 51/117 (43%), Positives = 61/117 (52%), Gaps = 8/117 (6%)
Query: 747 DVDECA----AIPGLCA--PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNT 798
DV+ECA PG C PG FRC C GY PA G C DVDEC + +C NT
Sbjct: 744 DVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNT 803
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
GS+ C C +GY L D ++C D+DEC+ C NT GSY C C G+ G
Sbjct: 804 PGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVG 860
Score = 102 bits (244), Expect = 6e-21
Identities = 54/121 (44%), Positives = 64/121 (52%), Gaps = 8/121 (6%)
Query: 744 VFADVDEC---AAIP-GLCA--PGRFRCV-CGPGYRP-AGEVCADVDECAVRPPPCDQLC 795
V D+DEC ++ P G C PG F+C+ C PGYR G C DV+ECA P C
Sbjct: 700 VCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWC 759
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
N GS+ C C GY DG +C DVDECE ICSNT GS++C C GY
Sbjct: 760 ENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSR 819
Query: 856 D 856
D
Sbjct: 820 D 820
Score = 89.4 bits (212), Expect = 5e-17
Identities = 49/132 (37%), Positives = 60/132 (45%), Gaps = 6/132 (4%)
Query: 298 GGYECSCGAGWK-LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
G C G+K L C D +EC +P VC G+C N G Y C CP G +
Sbjct: 335 GEVGADCPQGYKRLNSTHCQDINECA-MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQ 393
Query: 357 CV---DERKELCYDEWEAG-RCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
C+ E K LC+ +C +L R CCCS G AWG C+RCP +A F
Sbjct: 394 CIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKE 453
Query: 413 ICQGGMGRPNLT 424
IC G G LT
Sbjct: 454 ICPAGKGYHILT 465
Score = 85.4 bits (202), Expect = 8e-16
Identities = 48/123 (39%), Positives = 61/123 (49%), Gaps = 16/123 (13%)
Query: 747 DVDECAAIPGLCA--------PGRFRCVCGPGYRPAGE---VCADVDECAVRPPPC-DQL 794
D++ECA P LC PG ++C C PGYR VC D+DEC P C D
Sbjct: 660 DLNECAK-PHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECR-DPSSCPDGK 717
Query: 795 CHNTDGSYDCL-CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C N GS+ C+ C+ GY + G CRDV+EC + C N GS+ C+C GY
Sbjct: 718 CENKPGSFKCIACQPGYR-SQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAP 776
Query: 854 RGD 856
D
Sbjct: 777 APD 779
Score = 83.4 bits (197), Expect = 3e-15
Identities = 44/105 (41%), Positives = 54/105 (51%), Gaps = 10/105 (9%)
Query: 756 GLCAPGR--FRCVCGPGYR--PAGEVCADVDECAVRP-PPCDQLCHNTDGSYDCLCRTGY 810
G C PG + C C PGYR P C DV+EC P P +C NT GSY+C C GY
Sbjct: 588 GECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGY 647
Query: 811 EL--DEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
L G +C D++EC + H C C N G Y+C+C GY
Sbjct: 648 RLHVGAGGRSCVDLNECAK-PHLCGDGGFCINFPGHYKCNCYPGY 691
Score = 82.6 bits (195), Expect = 5e-15
Identities = 49/150 (32%), Positives = 66/150 (44%), Gaps = 11/150 (7%)
Query: 3 WNE--EDQSCAGAVGVPQTKYL-CCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEY-- 57
W++ ED CAG + P + CCC G WGA C CPPRG+ +H + +
Sbjct: 1092 WSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWD 1151
Query: 58 INPVTNETKPIDEC----DIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDEC 113
+P+ P DE D C G C P G C C G++ D + C D+DEC
Sbjct: 1152 TSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDEC 1211
Query: 114 SW--GRPPCRGMAQCVNLPGAFECRCPPGY 141
R +CVN G+F C C G+
Sbjct: 1212 RELNQRGLLCKSERCVNTSGSFRCVCKAGF 1241
Score = 75.4 bits (177), Expect = 8e-13
Identities = 70/232 (30%), Positives = 93/232 (40%), Gaps = 31/232 (13%)
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
D+DEC + C G C NT G +RC C +P C+ +E P C
Sbjct: 1036 DVDECLDESN-CRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPE--RRDVCW 1092
Query: 486 NTRGGYECQCSPGFTQGPDQTCVDVDECAEGR---ASCTFRCHNTAGSFRCTCPYGYAVA 542
+ RG + C+ G GP T D C +GR A C AGS CP + +
Sbjct: 1093 SQRGE-DGMCA-GPLAGPALTFDDCC-CRQGRGWGAQCRPCPPRGAGSH---CPTSQSES 1146
Query: 543 AD---------GVHCRDIDECVQEPRVC---PHACENVVGSYICKCPEGYRRTSAPQDSE 590
G RD D ++ C C G +C+CP G++ + S
Sbjct: 1147 NSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDA----SR 1202
Query: 591 NACEDINECEEQED---LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRR 639
C DI+EC E LC C+NT GSF C C AGF S C+ +R
Sbjct: 1203 ARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQR 1254
Score = 72.1 bits (169), Expect = 8e-12
Identities = 44/147 (29%), Positives = 63/147 (42%), Gaps = 22/147 (14%)
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
V G CP+GY+R ++ C+DINEC +C G C+N GS+ C C G
Sbjct: 333 VRGEVGADCPQGYKRLNSTH-----CQDINECA-MPGVCRHGDCLNNPGSYRCVCPPGHS 386
Query: 628 PSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCC 687
T CI + +SL PE +T+ CCC
Sbjct: 387 LGPSRTQCIADKPEE--KSLCFRLVSPEHQCQHPLTT--------------RLTRQLCCC 430
Query: 688 TLGAAWGSECELCPAPGSPARLDLCTA 714
++G AWG+ C+ CP G+ A ++C A
Sbjct: 431 SVGKAWGARCQRCPTDGTAAFKEICPA 457
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/130 (34%), Positives = 58/130 (44%), Gaps = 19/130 (14%)
Query: 747 DVDEC----AAIPGLC--APGRFRCVCGPGYR-PAGEVCADVDECAVRPPPC--DQLCHN 797
D+DEC A I G C G +RC+C G+R G C D+DEC+ P C C N
Sbjct: 826 DIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKN 885
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVD------ECE---RDTHTCQQICSNTEGSYECSCE 848
GSY C+C G+ +D C +V+ EC DT C + + EC C
Sbjct: 886 LQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCS 945
Query: 849 DGYEKRGDAC 858
G GD C
Sbjct: 946 LG-AGWGDHC 954
Score = 66.1 bits (154), Expect = 5e-10
Identities = 37/95 (38%), Positives = 47/95 (49%), Gaps = 14/95 (14%)
Query: 386 ECCCSEGAAWGRY-CERCP----------APDSAEFMRICQGGMGRPNLT--QDLDECRV 432
+CC S G AWG+ C +CP P E C G R N T QD++EC +
Sbjct: 302 DCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAM 361
Query: 433 RPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
P VC G C+N GS+RC CP G+ L P C+
Sbjct: 362 -PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCI 395
Score = 63.7 bits (148), Expect = 3e-09
Identities = 42/138 (30%), Positives = 59/138 (42%), Gaps = 12/138 (8%)
Query: 75 PQLCKP-GTC-HDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC----VN 128
P KP G C DT CG + C + +WG+ C Q V
Sbjct: 270 PPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGT-AWGQSKCHKCPQLQYTGVQ 328
Query: 129 LPGAFE----CRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
PG CP GY+ S C+D++EC +C HGDC N GSYRC C PG++L
Sbjct: 329 KPGPVRGEVGADCPQGYKRLNST-HCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSL 387
Query: 185 RENVCRDVDECSRPRPVC 202
+ + + + + +C
Sbjct: 388 GPSRTQCIADKPEEKSLC 405
Score = 62.5 bits (145), Expect = 6e-09
Identities = 50/167 (29%), Positives = 69/167 (41%), Gaps = 16/167 (9%)
Query: 180 PGYTLRENVCRDV------DECSRPRPVCRNGTCENLP--GAYLCHCDDGFKAGPNNDCV 231
PG T +E+ C + +C + + G + P G C G+K + C
Sbjct: 295 PGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQ 354
Query: 232 DVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDE----CDELPHPCG 286
D+NEC G VCR+G C N GS+RC C PG++L C D E C L P
Sbjct: 355 DINECAMPG-VCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEH 413
Query: 287 RDGNPSCTN-TNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGE 332
+ +P T T CS G W +RC D +C G+
Sbjct: 414 QCQHPLTTRLTRQLCCCSVGKAWGARCQRC-PTDGTAAFKEICPAGK 459
Score = 60.5 bits (140), Expect = 2e-08
Identities = 26/70 (37%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 780 DVDECAVRPPP-CDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICS 837
D+DEC + C + C NT Y+C C+ G+ D + C DVDEC +++ +C
Sbjct: 993 DIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCE 1052
Query: 838 NTEGSYECSC 847
NT G Y C+C
Sbjct: 1053 NTRGGYRCAC 1062
Score = 56.4 bits (130), Expect = 4e-07
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 447 GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT 506
G +CP GY + C D +ECA+ P +C +G C N G Y C C PG + GP +T
Sbjct: 335 GEVGADCPQGYKRL-NSTHCQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Query: 507 -CV 508
C+
Sbjct: 393 QCI 395
Score = 49.6 bits (113), Expect = 5e-05
Identities = 24/53 (45%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
G CP GY + HC+DI+EC P VC H C N GSY C CP G+
Sbjct: 335 GEVGADCPQGYK-RLNSTHCQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGH 385
Score = 47.2 bits (107), Expect = 2e-04
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDEC----ERDTHTCQQICSNTEGSYECSCEDG 850
C G C C G++LD A C D+DEC +R + C NT GS+ C C+ G
Sbjct: 1181 CVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAG 1240
Query: 851 YEK 853
+ +
Sbjct: 1241 FAR 1243
Score = 46.8 bits (106), Expect = 3e-04
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 9/84 (10%)
Query: 23 CCCSVGHAWG-APCEACPP-------RGSPAHTALCGEKPGEYINPVTNETKPIDECDIM 74
CC S+G AWG + C CP + P + + P Y + + I+EC M
Sbjct: 303 CCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINEC-AM 361
Query: 75 PQLCKPGTCHDTPTGFQCGCDHGY 98
P +C+ G C + P ++C C G+
Sbjct: 362 PGVCRHGDCLNNPGSYRCVCPPGH 385
Score = 44.0 bits (99), Expect = 0.002
Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 2/74 (2%)
Query: 488 RGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVH 547
RG C G+ + C D++ECA C N GS+RC CP G+++
Sbjct: 334 RGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQ 393
Query: 548 CRDIDECVQEPRVC 561
C I + +E +C
Sbjct: 394 C--IADKPEEKSLC 405
Score = 39.1 bits (87), Expect = 0.066
Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 3/55 (5%)
Query: 767 CGPGYRPAGEV-CADVDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDEDGANC 819
C GY+ C D++ECA+ P C C N GSY C+C G+ L C
Sbjct: 341 CPQGYKRLNSTHCQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC 394
Score = 34.3 bits (75), Expect = 1.9
Identities = 28/102 (27%), Positives = 39/102 (38%), Gaps = 20/102 (19%)
Query: 678 GHVTKAQCCCTLGAAWG-SECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXX 736
G + CC ++G AWG S+C CP +L P
Sbjct: 296 GLTKQEDCCGSIGTAWGQSKCHKCP------QLQYTGVQKPGPVRGEVGADCPQGYKRLN 349
Query: 737 XXXXXLDVFADVDECAAIPGLCA-------PGRFRCVCGPGY 771
D++ECA +PG+C PG +RCVC PG+
Sbjct: 350 STHCQ-----DINECA-MPGVCRHGDCLNNPGSYRCVCPPGH 385
Score = 33.9 bits (74), Expect = 2.5
Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C GY+ + +C+D++EC C N GSY C C G+
Sbjct: 341 CPQGYKR-LNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGH 385
Score = 33.9 bits (74), Expect = 2.5
Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 14/84 (16%)
Query: 782 DECAVRPPPCDQLCHNTDGSYDCLCRTG--YELDEDGANC-----RDVDECER-DTHTCQ 833
D C + P P + + LC G Y D + N RD+DEC + C+
Sbjct: 952 DHCEIYPCPV-----YSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICK 1006
Query: 834 Q-ICSNTEGSYECSCEDGYEKRGD 856
+ C NT+ YEC C+ G+ G+
Sbjct: 1007 EGKCVNTQPGYECYCKQGFYYDGN 1030
>M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein.
Length = 1394
Score = 377 bits (928), Expect = e-104
Identities = 248/726 (34%), Positives = 330/726 (45%), Gaps = 92/726 (12%)
Query: 152 DVDECG-DQRICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCE 208
+++EC + IC G C N Y C C GY E C D+DEC++ + +C G CE
Sbjct: 546 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 605
Query: 209 NLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCE-CAPGYTLT 266
N G++LC C GF A +C+DV+EC VC G C NTVG+FRCE C GY +T
Sbjct: 606 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPD-VCGEGHCVNTVGAFRCEYCDSGYRMT 664
Query: 267 ADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC-SCGAGWKLVGRRCVDRDECKELP 325
GR C D+DEC P C + C N+ G Y+C C G++ +C+D DEC E P
Sbjct: 665 QRGR-CEDIDECLN-PSTCPDE---QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE-P 718
Query: 326 YVCAGGECRNFNGGYVCECPAGWRFDKTAAVC--VDERKE--LCYDEWEAGRCHRARPLQ 381
VCA G+C N G Y+C C G+ C +DE ++ LC + G+C
Sbjct: 719 NVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVN----GQCKNTE--- 771
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
C C +G ++C +D+DEC+ R +C G+
Sbjct: 772 -GSFRCTCGQGYQLSAAKDQC----------------------EDIDECQHR-HLCAHGQ 807
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
C NT+GSF+C C GY + G C D +EC D +C G C NT G Y+C C GF
Sbjct: 808 CRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL 867
Query: 502 GPDQTCVDVDECAE-GRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRV 560
++TC D++EC G C NT GSF C C G++++ADG C DIDECV
Sbjct: 868 DDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVC 927
Query: 561 CPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFL 619
H C+N GS+ C C +G++ APQD + C D+NECE +C C N +GSFL
Sbjct: 928 DSHGFCDNTAGSFRCLCYQGFQ---APQDGQ-GCVDVNECELLSGVCGEAFCENVEGSFL 983
Query: 620 CDC-DAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXG 678
C C D E S C RT T L +P+
Sbjct: 984 CVCADENQEYSPMTGQC-RSRTST---DLDVDVDQPK-EEKKECYYNLNDASLCDNVLAP 1038
Query: 679 HVTKAQCCCTLGAAWGSECEL--CPAPGSPARLDLC-TAVNLTPXXXXXXXXXXXXXXXX 735
+VTK +CCCT GA WG CE+ CP G+ ++C P
Sbjct: 1039 NVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGG------ 1092
Query: 736 XXXXXXLDVFADVDECAAI------PGLCAPGR--FRCVCGPG--YRPAGEVCADVDECA 785
+ + D DEC G C R + C C G Y P C D+DEC
Sbjct: 1093 -------ENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ 1145
Query: 786 VRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECER--DTHTCQQIC-SNTE 840
P C D C NT+GSY+C C LD C R + E+ +T Q +C +
Sbjct: 1146 -DPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLS 1204
Query: 841 GSYECS 846
Y CS
Sbjct: 1205 DEYVCS 1210
Score = 328 bits (807), Expect = 4e-89
Identities = 268/842 (31%), Positives = 346/842 (41%), Gaps = 118/842 (14%)
Query: 46 HTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSH 105
+T +C E G + + IDEC + LC G C +T F C C G+
Sbjct: 569 YTCICYE--GYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGT 626
Query: 106 LCRDVDECSWGRPPCRGMAQCVNLPGAFECR-CPPGYRLTPSLDECEDVDECGDQRICDH 164
C DVDEC RP G CVN GAF C C GYR+T CED+DEC + C
Sbjct: 627 NCIDVDECL--RPDVCGEGHCVNTVGAFRCEYCDSGYRMTQR-GRCEDIDECLNPSTCPD 683
Query: 165 GDCRNTIGSYRC-ECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK 223
C N+ GSY+C C G+ C DVDEC P VC NG C NL G+Y+C C G+
Sbjct: 684 EQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN-VCANGDCSNLEGSYMCSCHKGYT 742
Query: 224 AGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELP 282
P++ C D++EC++G + C NG+C+NT GSFRC C GY L+A C D+DEC
Sbjct: 743 RTPDHKHCRDIDECQQGNL-CVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHR- 800
Query: 283 HPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGECRNFNGGY 340
H C C NT G ++C C G++ +G C D +EC E VC G+C N G Y
Sbjct: 801 HLCAHG---QCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSY 857
Query: 341 VCECPAGWRFDKTAAVCVD----ERKELCYDEWEAGRCHRARPLQLARPECCCSEG---A 393
C CP G++ D C D E LC + G C C C +G +
Sbjct: 858 DCTCPDGFQLDDNKT-CQDINECEHPGLCGPQ---GECLNTE----GSFHCVCQQGFSIS 909
Query: 394 AWGRYCE---RC---PAPDS--------AEFMRICQGGMGRPNLTQ---DLDECRVRPDV 436
A GR CE C DS F +C G P Q D++EC + V
Sbjct: 910 ADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGV 969
Query: 437 CVGGRCVNTDGSFRCECPD-GYVLAPDGLSC---------VDAD-------ECAL---DP 476
C C N +GSF C C D +P C VD D EC D
Sbjct: 970 CGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDA 1029
Query: 477 RICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAE-GRASCTFRCHNTAGSFRCTC 535
+C N N EC C+ G G + C ++ C G A T C G
Sbjct: 1030 SLCDNVLAPNVTK-QECCCTSGAGWGDN--C-EIFPCPVLGTAEFTEMCPKGKGFV---- 1081
Query: 536 PYGYAVA-ADGVHCRDIDECVQ-EPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENA 592
P G + + A G + +D DEC+ +C + C N Y C C +G + +
Sbjct: 1082 PAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQG----TYYDPVKLQ 1137
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRC 652
C D++EC++ C G C+NT+GS+ C C P D ++R C R S
Sbjct: 1138 CFDMDECQDPSS-CIDGQCVNTEGSYNCFCT---HPMV--LDASEKR---CIRPAESNEQ 1188
Query: 653 --EPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLD 710
E + T +CCC G AWG +C LCP S
Sbjct: 1189 IEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQ 1248
Query: 711 LC---TAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFAD------VDECAAIPGLCAPG 761
LC P D F + +EC + G C G
Sbjct: 1249 LCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-CENG 1307
Query: 762 R-------FRCVCGPGYR--PAGEVCADVDECAV---RPPPC-DQLCHNTDGSYDCLCRT 808
R + C C GY A C DV+EC R C + C NTDGSY CLC
Sbjct: 1308 RCVRVQEGYTCDCLDGYHLDTAKMTCFDVNECDELNNRMSLCKNAKCINTDGSYKCLCLP 1367
Query: 809 GY 810
GY
Sbjct: 1368 GY 1369
Score = 319 bits (784), Expect = 2e-86
Identities = 175/476 (36%), Positives = 236/476 (49%), Gaps = 44/476 (9%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
I+EC + P +C G C + P + C C GY C D+DEC+ + C +C
Sbjct: 547 INECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC-SQGRCE 605
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCE-CKPGYTL-R 185
N G+F C CP G+ + C DVDEC +C G C NT+G++RCE C GY + +
Sbjct: 606 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 665
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLC-HCDDGFKAGPNNDCVDVNECREGGMVCR 244
C D+DEC P C + C N PG+Y C C +GF+ G N C+DV+EC E VC
Sbjct: 666 RGRCEDIDECLNP-STCPDEQCVNSPGSYQCVPCTEGFR-GWNGQCLDVDECLEPN-VCA 722
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
NG C N GS+ C C GYT T D ++CRD+DEC + + C N C NT G + C+C
Sbjct: 723 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQ-GNLC---VNGQCKNTEGSFRCTC 778
Query: 305 GAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
G G++L + C D DEC+ ++CA G+CRN G + C C G+R C D +
Sbjct: 779 GQGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE 837
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPN 422
C ++ C R + A G Y CP + + C
Sbjct: 838 --CLEDKSV--CQRGDCINTA------------GSYDCTCPDGFQLDDNKTC-------- 873
Query: 423 LTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGN 481
QD++EC P +C G C+NT+GSF C C G+ ++ DG +C D DEC + +
Sbjct: 874 --QDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSH 930
Query: 482 GTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASC-TFRCHNTAGSFRCTC 535
G C NT G + C C GF D Q CVDV+EC C C N GSF C C
Sbjct: 931 GFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 986
Score = 172 bits (418), Expect = 5e-42
Identities = 153/536 (28%), Positives = 215/536 (40%), Gaps = 69/536 (12%)
Query: 63 NET-KPIDECDIMPQLCKP-GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
N+T + I+EC+ P LC P G C +T F C C G+ C D+DEC C
Sbjct: 870 NKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECV-NNTVC 927
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCEC- 178
C N G+F C C G++ C DV+EC +C C N GS+ C C
Sbjct: 928 DSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCA 987
Query: 179 --KPGYTLRENVCR---------DVDECSRPRPVCRNGT-----CENLPGAYL----CHC 218
Y+ CR DVD+ + C C+N+ + C C
Sbjct: 988 DENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCC 1047
Query: 219 DDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC 278
G AG ++C ++ C G C G A + A G N +D DEC
Sbjct: 1048 TSG--AGWGDNC-EIFPCPVLGTAEFTEMCPKGKGFVP---AGESSSEAGGENYKDADEC 1101
Query: 279 DELPHPCGRDGNPSCTNTNGGYECSCGAG--WKLVGRRCVDRDECKELPYVCAGGECRNF 336
++G C NT GYEC C G + V +C D DEC++ P C G+C N
Sbjct: 1102 LLFGQEICKNG--FCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQD-PSSCIDGQCVNT 1158
Query: 337 NGGYVCECPAGWRFDKTAAVCV------------DERKELCYDEWEAGRCHRARPL---Q 381
G Y C C D + C+ D ++LC++ + +RPL Q
Sbjct: 1159 EGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHL-SDEYVCSRPLVGKQ 1217
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
ECCC G AWG C CP DS ++ ++C N+ D V
Sbjct: 1218 TTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC-------NIPVTGRRQPYGRDALVDFS 1270
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGF-T 500
T + D ++ + + A+EC + C NG C + GY C C G+
Sbjct: 1271 EQYTPEADPYFIQDRFL---NSFEELQAEECGI-LNGCENGRCVRVQEGYTCDCLDGYHL 1326
Query: 501 QGPDQTCVDVDECAE--GRAS-C-TFRCHNTAGSFRCTCPYGYAVAADGVHCRDID 552
TC DV+EC E R S C +C NT GS++C C GY + +C ++
Sbjct: 1327 DTAKMTCFDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1382
Score = 170 bits (414), Expect = 2e-41
Identities = 87/237 (36%), Positives = 117/237 (49%), Gaps = 13/237 (5%)
Query: 421 PNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG 480
P +++EC V PD+C G C+N + C C +GY + CVD DEC +C
Sbjct: 541 PTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCS 600
Query: 481 NGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCT-CPYG 538
G C NT G + C C GF + T C+DVDEC C NT G+FRC C G
Sbjct: 601 QGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSG 660
Query: 539 YAVAADGVHCRDIDECVQEPRVCP-HACENVVGSYIC-KCPEGYRRTSAPQDSENACEDI 596
Y + G C DIDEC+ P CP C N GSY C C EG+R + C D+
Sbjct: 661 YRMTQRG-RCEDIDECL-NPSTCPDEQCVNSPGSYQCVPCTEGFRGWN------GQCLDV 712
Query: 597 NECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCE 653
+EC E ++C+ G C N +GS++C C G+ + D C D V+G+C+
Sbjct: 713 DECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK 768
Score = 152 bits (369), Expect = 4e-36
Identities = 154/574 (26%), Positives = 220/574 (38%), Gaps = 70/574 (12%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPP-CRGMAQC 126
I+EC +C+ G C +T + C C G++ D+ C+D++EC P C +C
Sbjct: 835 INECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNK-TCQDINECE--HPGLCGPQGEC 891
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICD-HGDCRNTIGSYRCECKPGYTLR 185
+N G+F C C G+ ++ CED+DEC + +CD HG C NT GS+RC C G+
Sbjct: 892 LNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAP 951
Query: 186 ENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHC-DDGFKAGP-NNDC---------VD 232
++ C DV+EC VC CEN+ G++LC C D+ + P C VD
Sbjct: 952 QDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVD 1011
Query: 233 VNECREGGMVCRNGR-----CRNT----VGSFRCECAPGYTLTADGRNCRDVDECDELPH 283
V++ +E C C N V C C G G NC ++ C L
Sbjct: 1012 VDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG---AGWGDNC-EIFPCPVLGT 1067
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPY-VCAGGECRNFNGGYVC 342
+ P E S AG G D DEC +C G C N GY C
Sbjct: 1068 AEFTEMCPKGKGFVPAGESSSEAG----GENYKDADECLLFGQEICKNGFCLNTRPGYEC 1123
Query: 343 ECPAGWRFDKTAAVCVDERKELCYDEWEA--GRCHRARPLQLARPECCCSEGAAWGRYCE 400
C G +D C D + C D G+C C C+ +
Sbjct: 1124 YCKQGTYYDPVKLQCFD--MDECQDPSSCIDGQCVNTE----GSYNCFCTHPMVLDASEK 1177
Query: 401 RCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLA 460
RC P + +I + + + + L + V VG + T+ C C G
Sbjct: 1178 RCIRPAESN-EQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTE----CCCLYGEAWG 1232
Query: 461 PDGLSCV--DADECALDPRI--------CGNGTCSNTRGGYECQCSPGFTQGPDQTCVD- 509
C D+D+ A I G + Y + P F Q +
Sbjct: 1233 MQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEE 1292
Query: 510 --VDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ---EPRVCPHA 564
+EC RC + C C GY + + C D++EC + +C +A
Sbjct: 1293 LQAEECGILNGCENGRCVRVQEGYTCDCLDGYHLDTAKMTCFDVNECDELNNRMSLCKNA 1352
Query: 565 -CENVVGSYICKCPEGYRRTSAPQDSENACEDIN 597
C N GSY C C GY P D N C +N
Sbjct: 1353 KCINTDGSYKCLCLPGY----VPSDKPNYCTPLN 1382
Score = 102 bits (245), Expect = 5e-21
Identities = 48/115 (41%), Positives = 64/115 (55%), Gaps = 9/115 (7%)
Query: 747 DVDECA----AIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNT 798
D+DEC + G C G FRC CG GY+ A + C D+DEC R C NT
Sbjct: 752 DIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNT 811
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE 852
+GS+ C+C GY G +C D++EC D CQ+ C NT GSY+C+C DG++
Sbjct: 812 EGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ 866
Score = 93.5 bits (222), Expect = 3e-18
Identities = 47/115 (40%), Positives = 62/115 (53%), Gaps = 11/115 (9%)
Query: 747 DVDECAAIPGLC-------APGRFRCV-CGPGYRPAGEVCADVDECAVRPPPC-DQLCHN 797
D+DEC P C +PG ++CV C G+R C DVDEC + P C + C N
Sbjct: 671 DIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDEC-LEPNVCANGDCSN 728
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+GSY C C GY D +CRD+DEC++ C NTEGS+ C+C GY+
Sbjct: 729 LEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQ 783
Score = 93.5 bits (222), Expect = 3e-18
Identities = 49/116 (42%), Positives = 62/116 (53%), Gaps = 15/116 (12%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQ--L 794
D++EC PGLC P G F CVC G+ + G C D+DEC V CD
Sbjct: 875 DINECEH-PGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGF 932
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCED 849
C NT GS+ CLC G++ +DG C DV+ECE + C + C N EGS+ C C D
Sbjct: 933 CDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCAD 988
Score = 91.1 bits (216), Expect = 2e-17
Identities = 44/116 (37%), Positives = 62/116 (53%), Gaps = 11/116 (9%)
Query: 747 DVDECAAIPGLCAPG-------RFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQ-LCH 796
+++EC P +C G R+ C+C GYR + + C D+DEC C Q C
Sbjct: 546 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 605
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGY 851
NT+GS+ C+C G+ E+G NC DVDEC R + C NT G++ C C+ GY
Sbjct: 606 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGY 661
Score = 90.6 bits (215), Expect = 2e-17
Identities = 66/183 (36%), Positives = 82/183 (44%), Gaps = 15/183 (8%)
Query: 246 GRC-RNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
GRC + T+GS + PG + D C + PS N EC
Sbjct: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPK--KPSYHGYNQMMECL- 287
Query: 305 GAGWKLVGRR-CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV----- 358
G+K V C D +EC +L VC GEC N G Y C C G+ D T + CV
Sbjct: 288 -PGYKRVNNTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV 345
Query: 359 -DERKELCYDEWEAGR-CHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
E K CY +GR C + L + CCCS G A G +CE+CP P +A F IC G
Sbjct: 346 ISEEKGPCYRLVSSGRQCMYPLSVHLTKQLCCCSVGKA-GPHCEKCPLPGTAAFKEICPG 404
Query: 417 GMG 419
GMG
Sbjct: 405 GMG 407
Score = 90.6 bits (215), Expect = 2e-17
Identities = 47/119 (39%), Positives = 60/119 (50%), Gaps = 12/119 (10%)
Query: 747 DVDECAAIPGLCA-------PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHN 797
DVDEC P +CA G + C C GY P + C D+DEC + C N
Sbjct: 711 DVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKN 769
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRG 855
T+GS+ C C GY+L C D+DEC+ H C C NTEGS++C C+ GY G
Sbjct: 770 TEGSFRCTCGQGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASG 827
Score = 86.2 bits (204), Expect = 4e-16
Identities = 90/310 (29%), Positives = 124/310 (40%), Gaps = 31/310 (10%)
Query: 38 CPPRGSPAHTA---LCGEKPGEYINPVTNETKPIDECDIMPQLCKP-GTCHDTPTGFQCG 93
C P+G +T C + G I+ + IDEC + +C G C +T F+C
Sbjct: 885 CGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCL 943
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPP-GYRLTPSLDECE- 151
C G++ C DV+EC C G A C N+ G+F C C +P +C
Sbjct: 944 CYQGFQAPQDGQGCVDVNECELLSGVC-GEAFCENVEGSFLCVCADENQEYSPMTGQCRS 1002
Query: 152 ----DVDECGDQRICDHGDCR-NTIGSYRCE--CKPGYTLRENVCRDV----DECSR-PR 199
D+D DQ + +C N + C+ P T +E C D C P
Sbjct: 1003 RTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPC 1062
Query: 200 PVCRNGT-CENLPGA--YLCHCDDGFKAGPNNDCVDVNECREGGM-VCRNGRCRNTVGSF 255
PV E P ++ + +AG N D +EC G +C+NG C NT +
Sbjct: 1063 PVLGTAEFTEMCPKGKGFVPAGESSSEAGGEN-YKDADECLLFGQEICKNGFCLNTRPGY 1121
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--R 313
C C G C D+DEC + P C DG C NT G Y C C L +
Sbjct: 1122 ECYCKQGTYYDPVKLQCFDMDECQD-PSSC-IDG--QCVNTEGSYNCFCTHPMVLDASEK 1177
Query: 314 RCVDRDECKE 323
RC+ E E
Sbjct: 1178 RCIRPAESNE 1187
Score = 83.4 bits (197), Expect = 3e-15
Identities = 58/167 (34%), Positives = 73/167 (43%), Gaps = 12/167 (7%)
Query: 3 WNEEDQSCAGAVGVPQ-TKYLCCCSVGHAWGAPCEA--CPPRGSPAHTALC----GEKP- 54
+N D S V P TK CCC+ G WG CE CP G+ T +C G P
Sbjct: 1024 YNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPA 1083
Query: 55 GEYINPVTNET-KPIDECDIMPQ-LCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDE 112
GE + E K DEC + Q +CK G C +T G++C C G +D C D+DE
Sbjct: 1084 GESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDE 1143
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQ 159
C P QCVN G++ C C L S C E +Q
Sbjct: 1144 CQ--DPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQ 1188
Score = 83.0 bits (196), Expect = 4e-15
Identities = 42/127 (33%), Positives = 63/127 (49%), Gaps = 16/127 (12%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYR-PAGEVCADVDECAVRPPPCDQL--CH 796
D++EC +C G + C C G++ + C D++EC P C C
Sbjct: 834 DINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECL 892
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE-- 852
NT+GS+ C+C+ G+ + DG C D+DEC +T C C NT GS+ C C G++
Sbjct: 893 NTEGSFHCVCQQGFSISADGRTCEDIDECVNNT-VCDSHGFCDNTAGSFRCLCYQGFQAP 951
Query: 853 KRGDACV 859
+ G CV
Sbjct: 952 QDGQGCV 958
Score = 81.0 bits (191), Expect = 2e-14
Identities = 50/121 (41%), Positives = 58/121 (47%), Gaps = 15/121 (12%)
Query: 747 DVDECAAIPGLCAPGR-------FRC-VCGPGYRPAGEV-CADVDECAVRPPPC-DQLCH 796
DVDEC P +C G FRC C GYR C D+DEC + P C D+ C
Sbjct: 630 DVDECLR-PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDEC-LNPSTCPDEQCV 687
Query: 797 NTDGSYDCL-CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
N+ GSY C+ C G+ C DVDEC CSN EGSY CSC GY +
Sbjct: 688 NSPGSYQCVPCTEGFR--GWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTP 745
Query: 856 D 856
D
Sbjct: 746 D 746
Score = 78.6 bits (185), Expect = 9e-14
Identities = 54/182 (29%), Positives = 77/182 (42%), Gaps = 22/182 (12%)
Query: 6 EDQSCAGAVGVPQTKYL-CCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNE 64
++ C+ + QT Y CCC G AWG C CP + S + LC PVT
Sbjct: 1205 DEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCN-------IPVTGR 1257
Query: 65 TKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+P D + + T P Q + +E + + C ++ C GR
Sbjct: 1258 RQPYGR-DALVDFSEQYTPEADPYFIQDRFLNSFE-ELQAEECGILNGCENGR------- 1308
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECEDVDECGD----QRICDHGDCRNTIGSYRCECKP 180
CV + + C C GY L + C DV+EC + +C + C NT GSY+C C P
Sbjct: 1309 -CVRVQEGYTCDCLDGYHLDTAKMTCFDVNECDELNNRMSLCKNAKCINTDGSYKCLCLP 1367
Query: 181 GY 182
GY
Sbjct: 1368 GY 1369
Score = 77.8 bits (183), Expect = 2e-13
Identities = 59/194 (30%), Positives = 81/194 (41%), Gaps = 19/194 (9%)
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWG-RYCERCPAPDSAEF---MRICQGGMGR 420
C+ E +C +A P + +CC + G +WG C++CP S M C G R
Sbjct: 233 CFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKR 292
Query: 421 PNLT--QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRI 478
N T QD++EC+++ VC G C+NT GS+RC C G+ P SCV DP +
Sbjct: 293 VNNTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVP------DPPV 345
Query: 479 CG--NGTCSN-TRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
G C G +C C V + C TA +F+ C
Sbjct: 346 ISEEKGPCYRLVSSGRQCMYPLSVHLTKQLCCCSVGKAGPHCEKCPL--PGTA-AFKEIC 402
Query: 536 PYGYAVAADGVHCR 549
P G GVH R
Sbjct: 403 PGGMGYTVSGVHRR 416
Score = 77.0 bits (181), Expect = 3e-13
Identities = 49/144 (34%), Positives = 65/144 (45%), Gaps = 32/144 (22%)
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTD 634
+C GY+R + C+DINEC+ Q +C G C+NT GS+ C C GF P +
Sbjct: 285 ECLPGYKRVN-----NTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSS 338
Query: 635 C------IDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCT 688
C I G CYR + SGR H+TK CCC+
Sbjct: 339 CVPDPPVISEEKGPCYRLVSSGR-------------------QCMYPLSVHLTKQLCCCS 379
Query: 689 LGAAWGSECELCPAPGSPARLDLC 712
+G A G CE CP PG+ A ++C
Sbjct: 380 VGKA-GPHCEKCPLPGTAAFKEIC 402
Score = 62.1 bits (144), Expect = 8e-09
Identities = 34/103 (33%), Positives = 49/103 (47%), Gaps = 4/103 (3%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC-RCPP 139
G C G QCG + C SWG C+ + + G + C P
Sbjct: 231 GRCFQETIGSQCG--KALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLP 288
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY 182
GY+ + C+D++EC Q +C +G+C NT+GSYRC CK G+
Sbjct: 289 GYKRVNNTF-CQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
Score = 60.5 bits (140), Expect = 2e-08
Identities = 44/129 (34%), Positives = 59/129 (45%), Gaps = 10/129 (7%)
Query: 165 GDC-RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAY----LCHCD 219
G C + TIGS + PG + +E+ C V S C+ C P + + C
Sbjct: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGT-SWGFNKCQK--CPKKPSYHGYNQMMECL 287
Query: 220 DGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDEC 278
G+K N C D+NEC+ G VC NG C NT+GS+RC C G+ +C D
Sbjct: 288 PGYKRVNNTFCQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVI 346
Query: 279 DELPHPCGR 287
E PC R
Sbjct: 347 SEEKGPCYR 355
Score = 59.3 bits (137), Expect = 6e-08
Identities = 30/79 (37%), Positives = 38/79 (48%), Gaps = 7/79 (8%)
Query: 565 CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED---LCSGGVCINTDGSFLCD 621
C V Y C C +GY +A C D+NEC+E + LC CINTDGS+ C
Sbjct: 1309 CVRVQEGYTCDCLDGYHLDTAKM----TCFDVNECDELNNRMSLCKNAKCINTDGSYKCL 1364
Query: 622 CDAGFEPSEDGTDCIDRRT 640
C G+ PS+ C T
Sbjct: 1365 CLPGYVPSDKPNYCTPLNT 1383
Score = 58.8 bits (136), Expect = 8e-08
Identities = 34/93 (36%), Positives = 42/93 (45%), Gaps = 10/93 (10%)
Query: 765 CVCGPGYRPAGEVCA--------DVDECAVRPPP-CDQ-LCHNTDGSYDCLCRTGYELDE 814
C G G+ PAGE + D DEC + C C NT Y+C C+ G D
Sbjct: 1074 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDP 1133
Query: 815 DGANCRDVDECERDTHTCQQICSNTEGSYECSC 847
C D+DEC+ + C NTEGSY C C
Sbjct: 1134 VKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFC 1166
Score = 50.8 bits (116), Expect = 2e-05
Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 4/74 (5%)
Query: 782 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTH---TCQQI-CS 837
+EC + + C Y C C GY LD C DV+EC+ + C+ C
Sbjct: 1296 EECGILNGCENGRCVRVQEGYTCDCLDGYHLDTAKMTCFDVNECDELNNRMSLCKNAKCI 1355
Query: 838 NTEGSYECSCEDGY 851
NT+GSY+C C GY
Sbjct: 1356 NTDGSYKCLCLPGY 1369
Score = 48.8 bits (111), Expect = 8e-05
Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCI 636
PE +++ + +INEC D+C G CIN + C C G+ SE C+
Sbjct: 528 PEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCV 587
Query: 637 DRRTGTCYRSLVS-GRCE 653
D T + L S GRCE
Sbjct: 588 DIDECTQVQHLCSQGRCE 605
Score = 44.4 bits (100), Expect = 0.002
Identities = 36/131 (27%), Positives = 54/131 (41%), Gaps = 10/131 (7%)
Query: 23 CCCSVGHAWGA-PCEACPPRGS-PAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKP 80
CC +VG +WG C+ CP + S + + PG Y + I+EC + +C
Sbjct: 255 CCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPG-YKRVNNTFCQDINECQLQG-VCPN 312
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
G C +T ++C C G+ D T C D S + PC + + +C P
Sbjct: 313 GECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRL-----VSSGRQCMYPL 367
Query: 140 GYRLTPSLDEC 150
LT L C
Sbjct: 368 SVHLTKQLCCC 378
Score = 44.0 bits (99), Expect = 0.002
Identities = 24/61 (39%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 8 QSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKP 67
+ C + V TK LCCCSVG A G CE CP G+ A +C G ++ V + +P
Sbjct: 361 RQCMYPLSVHLTKQLCCCSVGKA-GPHCEKCPLPGTAAFKEICPGGMGYTVSGV-HRRRP 418
Query: 68 I 68
I
Sbjct: 419 I 419
Score = 42.7 bits (96), Expect = 0.005
Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 767 CGPGYRPAGEV-CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
C PGY+ C D++EC ++ + C NT GSY C C+ G+ D ++C
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
Score = 38.3 bits (85), Expect = 0.11
Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 535 CPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
C GY + C+DI+EC Q VCP+ C N +GSY C C G+
Sbjct: 286 CLPGYK-RVNNTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGF 330
Score = 37.1 bits (82), Expect = 0.27
Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C GY+ + C+D++EC+ C NT GSY C+C+ G+
Sbjct: 286 CLPGYKR-VNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
>BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming growth
factor beta binding protein 1 protein.
Length = 1395
Score = 377 bits (928), Expect = e-104
Identities = 248/726 (34%), Positives = 330/726 (45%), Gaps = 92/726 (12%)
Query: 152 DVDECG-DQRICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCE 208
+++EC + IC G C N Y C C GY E C D+DEC++ + +C G CE
Sbjct: 547 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 606
Query: 209 NLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCE-CAPGYTLT 266
N G++LC C GF A +C+DV+EC VC G C NTVG+FRCE C GY +T
Sbjct: 607 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPD-VCGEGHCVNTVGAFRCEYCDSGYRMT 665
Query: 267 ADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC-SCGAGWKLVGRRCVDRDECKELP 325
GR C D+DEC P C + C N+ G Y+C C G++ +C+D DEC E P
Sbjct: 666 QRGR-CEDIDECLN-PSTCPDE---QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE-P 719
Query: 326 YVCAGGECRNFNGGYVCECPAGWRFDKTAAVC--VDERKE--LCYDEWEAGRCHRARPLQ 381
VCA G+C N G Y+C C G+ C +DE ++ LC + G+C
Sbjct: 720 NVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVN----GQCKNTE--- 772
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
C C +G ++C +D+DEC+ R +C G+
Sbjct: 773 -GSFRCTCGQGYQLSAAKDQC----------------------EDIDECQHR-HLCAHGQ 808
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
C NT+GSF+C C GY + G C D +EC D +C G C NT G Y+C C GF
Sbjct: 809 CRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL 868
Query: 502 GPDQTCVDVDECAE-GRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRV 560
++TC D++EC G C NT GSF C C G++++ADG C DIDECV
Sbjct: 869 DDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVC 928
Query: 561 CPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFL 619
H C+N GS+ C C +G++ APQD + C D+NECE +C C N +GSFL
Sbjct: 929 DSHGFCDNTAGSFRCLCYQGFQ---APQDGQ-GCVDVNECELLSGVCGEAFCENVEGSFL 984
Query: 620 CDC-DAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXG 678
C C D E S C RT T L +P+
Sbjct: 985 CVCADENQEYSPMTGQC-RSRTST---DLDVDVDQPK-EEKKECYYNLNDASLCDNVLAP 1039
Query: 679 HVTKAQCCCTLGAAWGSECEL--CPAPGSPARLDLC-TAVNLTPXXXXXXXXXXXXXXXX 735
+VTK +CCCT GA WG CE+ CP G+ ++C P
Sbjct: 1040 NVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGG------ 1093
Query: 736 XXXXXXLDVFADVDECAAI------PGLCAPGR--FRCVCGPG--YRPAGEVCADVDECA 785
+ + D DEC G C R + C C G Y P C D+DEC
Sbjct: 1094 -------ENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ 1146
Query: 786 VRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECER--DTHTCQQIC-SNTE 840
P C D C NT+GSY+C C LD C R + E+ +T Q +C +
Sbjct: 1147 -DPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLS 1205
Query: 841 GSYECS 846
Y CS
Sbjct: 1206 DEYVCS 1211
Score = 330 bits (810), Expect = 2e-89
Identities = 268/842 (31%), Positives = 345/842 (40%), Gaps = 118/842 (14%)
Query: 46 HTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSH 105
+T +C E G + + IDEC + LC G C +T F C C G+
Sbjct: 570 YTCICYE--GYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGT 627
Query: 106 LCRDVDECSWGRPPCRGMAQCVNLPGAFECR-CPPGYRLTPSLDECEDVDECGDQRICDH 164
C DVDEC RP G CVN GAF C C GYR+T CED+DEC + C
Sbjct: 628 NCIDVDECL--RPDVCGEGHCVNTVGAFRCEYCDSGYRMTQR-GRCEDIDECLNPSTCPD 684
Query: 165 GDCRNTIGSYRC-ECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK 223
C N+ GSY+C C G+ C DVDEC P VC NG C NL G+Y+C C G+
Sbjct: 685 EQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN-VCANGDCSNLEGSYMCSCHKGYT 743
Query: 224 AGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELP 282
P++ C D++EC++G + C NG+C+NT GSFRC C GY L+A C D+DEC
Sbjct: 744 RTPDHKHCRDIDECQQGNL-CVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHR- 801
Query: 283 HPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGECRNFNGGY 340
H C C NT G ++C C G++ +G C D +EC E VC G+C N G Y
Sbjct: 802 HLCAHG---QCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSY 858
Query: 341 VCECPAGWRFDKTAAVCVD----ERKELCYDEWEAGRCHRARPLQLARPECCCSEG---A 393
C CP G++ D C D E LC + G C C C +G +
Sbjct: 859 DCTCPDGFQLDDNKT-CQDINECEHPGLCGPQ---GECLNTE----GSFHCVCQQGFSIS 910
Query: 394 AWGRYCE---RC---PAPDS--------AEFMRICQGGMGRPNLTQ---DLDECRVRPDV 436
A GR CE C DS F +C G P Q D++EC + V
Sbjct: 911 ADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGV 970
Query: 437 CVGGRCVNTDGSFRCECPD-GYVLAPDGLSC---------VDAD-------ECAL---DP 476
C C N +GSF C C D +P C VD D EC D
Sbjct: 971 CGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDA 1030
Query: 477 RICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAE-GRASCTFRCHNTAGSFRCTC 535
+C N N EC C+ G G + C ++ C G A T C G
Sbjct: 1031 SLCDNVLAPNVTK-QECCCTSGAGWGDN--C-EIFPCPVLGTAEFTEMCPKGKGFV---- 1082
Query: 536 PYGYAVA-ADGVHCRDIDECVQ-EPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENA 592
P G + + A G + +D DEC+ +C + C N Y C C +G + +
Sbjct: 1083 PAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQG----TYYDPVKLQ 1138
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRC 652
C D++EC++ C G C+NT+GS+ C C P D ++R C R S
Sbjct: 1139 CFDMDECQDPSS-CIDGQCVNTEGSYNCFCT---HPMV--LDASEKR---CIRPAESNEQ 1189
Query: 653 --EPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLD 710
E + T +CCC G AWG +C LCP S
Sbjct: 1190 IEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQ 1249
Query: 711 LCTAV---NLTPXXXXXXXXXXXXXXXXXXXXXXLDVFAD------VDECAAIPGLCAPG 761
LC P D F + +EC + G C G
Sbjct: 1250 LCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-CENG 1308
Query: 762 R-------FRCVCGPGYR--PAGEVCADVDECAV---RPPPCDQL-CHNTDGSYDCLCRT 808
R + C C GY A C DV+EC R C C NTDGSY CLC
Sbjct: 1309 RCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLP 1368
Query: 809 GY 810
GY
Sbjct: 1369 GY 1370
Score = 319 bits (784), Expect = 2e-86
Identities = 175/476 (36%), Positives = 236/476 (49%), Gaps = 44/476 (9%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
I+EC + P +C G C + P + C C GY C D+DEC+ + C +C
Sbjct: 548 INECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC-SQGRCE 606
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCE-CKPGYTL-R 185
N G+F C CP G+ + C DVDEC +C G C NT+G++RCE C GY + +
Sbjct: 607 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 666
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLC-HCDDGFKAGPNNDCVDVNECREGGMVCR 244
C D+DEC P C + C N PG+Y C C +GF+ G N C+DV+EC E VC
Sbjct: 667 RGRCEDIDECLNP-STCPDEQCVNSPGSYQCVPCTEGFR-GWNGQCLDVDECLEPN-VCA 723
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
NG C N GS+ C C GYT T D ++CRD+DEC + + C N C NT G + C+C
Sbjct: 724 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQ-GNLC---VNGQCKNTEGSFRCTC 779
Query: 305 GAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
G G++L + C D DEC+ ++CA G+CRN G + C C G+R C D +
Sbjct: 780 GQGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE 838
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPN 422
C ++ C R + A G Y CP + + C
Sbjct: 839 --CLEDKSV--CQRGDCINTA------------GSYDCTCPDGFQLDDNKTC-------- 874
Query: 423 LTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGN 481
QD++EC P +C G C+NT+GSF C C G+ ++ DG +C D DEC + +
Sbjct: 875 --QDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSH 931
Query: 482 GTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASC-TFRCHNTAGSFRCTC 535
G C NT G + C C GF D Q CVDV+EC C C N GSF C C
Sbjct: 932 GFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 987
Score = 174 bits (423), Expect = 1e-42
Identities = 154/536 (28%), Positives = 216/536 (40%), Gaps = 69/536 (12%)
Query: 63 NET-KPIDECDIMPQLCKP-GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
N+T + I+EC+ P LC P G C +T F C C G+ C D+DEC C
Sbjct: 871 NKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECV-NNTVC 928
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCEC- 178
C N G+F C C G++ C DV+EC +C C N GS+ C C
Sbjct: 929 DSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCA 988
Query: 179 --KPGYTLRENVCR---------DVDECSRPRPVCRNGT-----CENLPGAYL----CHC 218
Y+ CR DVD+ + C C+N+ + C C
Sbjct: 989 DENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCC 1048
Query: 219 DDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC 278
G AG ++C ++ C G C G A + A G N +D DEC
Sbjct: 1049 TSG--AGWGDNC-EIFPCPVLGTAEFTEMCPKGKGFVP---AGESSSEAGGENYKDADEC 1102
Query: 279 DELPHPCGRDGNPSCTNTNGGYECSCGAG--WKLVGRRCVDRDECKELPYVCAGGECRNF 336
++G C NT GYEC C G + V +C D DEC++ P C G+C N
Sbjct: 1103 LLFGQEICKNG--FCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQD-PSSCIDGQCVNT 1159
Query: 337 NGGYVCECPAGWRFDKTAAVCV------------DERKELCYDEWEAGRCHRARPL---Q 381
G Y C C D + C+ D ++LC++ + +RPL Q
Sbjct: 1160 EGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHL-SDEYVCSRPLVGKQ 1218
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
ECCC G AWG C CP DS ++ ++C N+ D V
Sbjct: 1219 TTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC-------NIPVTGRRQPYGRDALVDFS 1271
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGF-T 500
T + D ++ + + A+EC + C NG C + GY C C G+
Sbjct: 1272 EQYTPEADPYFIQDRFL---NSFEELQAEECGI-LNGCENGRCVRVQEGYTCDCFDGYHL 1327
Query: 501 QGPDQTCVDVDECAE--GRAS-C-TFRCHNTAGSFRCTCPYGYAVAADGVHCRDID 552
TCVDV+EC E R S C +C NT GS++C C GY + +C ++
Sbjct: 1328 DTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1383
Score = 170 bits (414), Expect = 2e-41
Identities = 87/237 (36%), Positives = 117/237 (49%), Gaps = 13/237 (5%)
Query: 421 PNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG 480
P +++EC V PD+C G C+N + C C +GY + CVD DEC +C
Sbjct: 542 PTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCS 601
Query: 481 NGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCT-CPYG 538
G C NT G + C C GF + T C+DVDEC C NT G+FRC C G
Sbjct: 602 QGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSG 661
Query: 539 YAVAADGVHCRDIDECVQEPRVCP-HACENVVGSYIC-KCPEGYRRTSAPQDSENACEDI 596
Y + G C DIDEC+ P CP C N GSY C C EG+R + C D+
Sbjct: 662 YRMTQRG-RCEDIDECL-NPSTCPDEQCVNSPGSYQCVPCTEGFRGWN------GQCLDV 713
Query: 597 NECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCE 653
+EC E ++C+ G C N +GS++C C G+ + D C D V+G+C+
Sbjct: 714 DECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK 769
Score = 152 bits (368), Expect = 6e-36
Identities = 154/574 (26%), Positives = 220/574 (38%), Gaps = 70/574 (12%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPP-CRGMAQC 126
I+EC +C+ G C +T + C C G++ D+ C+D++EC P C +C
Sbjct: 836 INECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNK-TCQDINECE--HPGLCGPQGEC 892
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICD-HGDCRNTIGSYRCECKPGYTLR 185
+N G+F C C G+ ++ CED+DEC + +CD HG C NT GS+RC C G+
Sbjct: 893 LNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAP 952
Query: 186 ENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHC-DDGFKAGP-NNDC---------VD 232
++ C DV+EC VC CEN+ G++LC C D+ + P C VD
Sbjct: 953 QDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVD 1012
Query: 233 VNECREGGMVCRNGR-----CRNT----VGSFRCECAPGYTLTADGRNCRDVDECDELPH 283
V++ +E C C N V C C G G NC ++ C L
Sbjct: 1013 VDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG---AGWGDNC-EIFPCPVLGT 1068
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPY-VCAGGECRNFNGGYVC 342
+ P E S AG G D DEC +C G C N GY C
Sbjct: 1069 AEFTEMCPKGKGFVPAGESSSEAG----GENYKDADECLLFGQEICKNGFCLNTRPGYEC 1124
Query: 343 ECPAGWRFDKTAAVCVDERKELCYDEWEA--GRCHRARPLQLARPECCCSEGAAWGRYCE 400
C G +D C D + C D G+C C C+ +
Sbjct: 1125 YCKQGTYYDPVKLQCFD--MDECQDPSSCIDGQCVNTE----GSYNCFCTHPMVLDASEK 1178
Query: 401 RCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLA 460
RC P + +I + + + + L + V VG + T+ C C G
Sbjct: 1179 RCIRPAESN-EQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTE----CCCLYGEAWG 1233
Query: 461 PDGLSCV--DADECALDPRI--------CGNGTCSNTRGGYECQCSPGFTQGPDQTCVD- 509
C D+D+ A I G + Y + P F Q +
Sbjct: 1234 MQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEE 1293
Query: 510 --VDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ---EPRVCPHA 564
+EC RC + C C GY + + C D++EC + +C +A
Sbjct: 1294 LQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNA 1353
Query: 565 -CENVVGSYICKCPEGYRRTSAPQDSENACEDIN 597
C N GSY C C GY P D N C +N
Sbjct: 1354 KCINTDGSYKCLCLPGY----VPSDKPNYCTPLN 1383
Score = 102 bits (245), Expect = 5e-21
Identities = 48/115 (41%), Positives = 64/115 (55%), Gaps = 9/115 (7%)
Query: 747 DVDECA----AIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNT 798
D+DEC + G C G FRC CG GY+ A + C D+DEC R C NT
Sbjct: 753 DIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNT 812
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE 852
+GS+ C+C GY G +C D++EC D CQ+ C NT GSY+C+C DG++
Sbjct: 813 EGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ 867
Score = 100 bits (239), Expect = 3e-20
Identities = 67/183 (36%), Positives = 83/183 (45%), Gaps = 14/183 (7%)
Query: 246 GRC-RNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
GRC + T+GS + PG + D C + PS N EC
Sbjct: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPK--KPSYHGYNQMMECL- 287
Query: 305 GAGWKLVGRR-CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV----- 358
G+K V C D +EC +L VC GEC N G Y C C G+ D T + CV
Sbjct: 288 -PGYKRVNNTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV 345
Query: 359 -DERKELCYDEWEAGR-CHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
E K CY +GR C + L + CCCS G AWG +CE+CP P +A F IC G
Sbjct: 346 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPG 405
Query: 417 GMG 419
GMG
Sbjct: 406 GMG 408
Score = 93.5 bits (222), Expect = 3e-18
Identities = 47/115 (40%), Positives = 62/115 (53%), Gaps = 11/115 (9%)
Query: 747 DVDECAAIPGLC-------APGRFRCV-CGPGYRPAGEVCADVDECAVRPPPC-DQLCHN 797
D+DEC P C +PG ++CV C G+R C DVDEC + P C + C N
Sbjct: 672 DIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDEC-LEPNVCANGDCSN 729
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+GSY C C GY D +CRD+DEC++ C NTEGS+ C+C GY+
Sbjct: 730 LEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQ 784
Score = 93.5 bits (222), Expect = 3e-18
Identities = 49/116 (42%), Positives = 62/116 (53%), Gaps = 15/116 (12%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQ--L 794
D++EC PGLC P G F CVC G+ + G C D+DEC V CD
Sbjct: 876 DINECEH-PGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGF 933
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCED 849
C NT GS+ CLC G++ +DG C DV+ECE + C + C N EGS+ C C D
Sbjct: 934 CDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCAD 989
Score = 91.1 bits (216), Expect = 2e-17
Identities = 44/116 (37%), Positives = 62/116 (53%), Gaps = 11/116 (9%)
Query: 747 DVDECAAIPGLCAPG-------RFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQ-LCH 796
+++EC P +C G R+ C+C GYR + + C D+DEC C Q C
Sbjct: 547 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 606
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGY 851
NT+GS+ C+C G+ E+G NC DVDEC R + C NT G++ C C+ GY
Sbjct: 607 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGY 662
Score = 90.6 bits (215), Expect = 2e-17
Identities = 47/119 (39%), Positives = 60/119 (50%), Gaps = 12/119 (10%)
Query: 747 DVDECAAIPGLCA-------PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHN 797
DVDEC P +CA G + C C GY P + C D+DEC + C N
Sbjct: 712 DVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKN 770
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRG 855
T+GS+ C C GY+L C D+DEC+ H C C NTEGS++C C+ GY G
Sbjct: 771 TEGSFRCTCGQGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASG 828
Score = 86.2 bits (204), Expect = 4e-16
Identities = 90/310 (29%), Positives = 124/310 (40%), Gaps = 31/310 (10%)
Query: 38 CPPRGSPAHTA---LCGEKPGEYINPVTNETKPIDECDIMPQLCKP-GTCHDTPTGFQCG 93
C P+G +T C + G I+ + IDEC + +C G C +T F+C
Sbjct: 886 CGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCL 944
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPP-GYRLTPSLDECE- 151
C G++ C DV+EC C G A C N+ G+F C C +P +C
Sbjct: 945 CYQGFQAPQDGQGCVDVNECELLSGVC-GEAFCENVEGSFLCVCADENQEYSPMTGQCRS 1003
Query: 152 ----DVDECGDQRICDHGDCR-NTIGSYRCE--CKPGYTLRENVCRDV----DECSR-PR 199
D+D DQ + +C N + C+ P T +E C D C P
Sbjct: 1004 RTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPC 1063
Query: 200 PVCRNGT-CENLPGA--YLCHCDDGFKAGPNNDCVDVNECREGGM-VCRNGRCRNTVGSF 255
PV E P ++ + +AG N D +EC G +C+NG C NT +
Sbjct: 1064 PVLGTAEFTEMCPKGKGFVPAGESSSEAGGEN-YKDADECLLFGQEICKNGFCLNTRPGY 1122
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--R 313
C C G C D+DEC + P C DG C NT G Y C C L +
Sbjct: 1123 ECYCKQGTYYDPVKLQCFDMDECQD-PSSC-IDG--QCVNTEGSYNCFCTHPMVLDASEK 1178
Query: 314 RCVDRDECKE 323
RC+ E E
Sbjct: 1179 RCIRPAESNE 1188
Score = 85.8 bits (203), Expect = 6e-16
Identities = 50/144 (34%), Positives = 66/144 (45%), Gaps = 31/144 (21%)
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTD 634
+C GY+R + C+DINEC+ Q +C G C+NT GS+ C C GF P +
Sbjct: 285 ECLPGYKRVN-----NTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSS 338
Query: 635 C------IDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCT 688
C I G CYR + SGR H+TK CCC+
Sbjct: 339 CVPDPPVISEEKGPCYRLVSSGR-------------------QCMHPLSVHLTKQLCCCS 379
Query: 689 LGAAWGSECELCPAPGSPARLDLC 712
+G AWG CE CP PG+ A ++C
Sbjct: 380 VGKAWGPHCEKCPLPGTAAFKEIC 403
Score = 83.4 bits (197), Expect = 3e-15
Identities = 58/167 (34%), Positives = 73/167 (43%), Gaps = 12/167 (7%)
Query: 3 WNEEDQSCAGAVGVPQ-TKYLCCCSVGHAWGAPCEA--CPPRGSPAHTALC----GEKP- 54
+N D S V P TK CCC+ G WG CE CP G+ T +C G P
Sbjct: 1025 YNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPA 1084
Query: 55 GEYINPVTNET-KPIDECDIMPQ-LCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDE 112
GE + E K DEC + Q +CK G C +T G++C C G +D C D+DE
Sbjct: 1085 GESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDE 1144
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQ 159
C P QCVN G++ C C L S C E +Q
Sbjct: 1145 CQ--DPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQ 1189
Score = 83.0 bits (196), Expect = 4e-15
Identities = 42/127 (33%), Positives = 63/127 (49%), Gaps = 16/127 (12%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYR-PAGEVCADVDECAVRPPPCDQL--CH 796
D++EC +C G + C C G++ + C D++EC P C C
Sbjct: 835 DINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECL 893
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE-- 852
NT+GS+ C+C+ G+ + DG C D+DEC +T C C NT GS+ C C G++
Sbjct: 894 NTEGSFHCVCQQGFSISADGRTCEDIDECVNNT-VCDSHGFCDNTAGSFRCLCYQGFQAP 952
Query: 853 KRGDACV 859
+ G CV
Sbjct: 953 QDGQGCV 959
Score = 81.0 bits (191), Expect = 2e-14
Identities = 50/121 (41%), Positives = 58/121 (47%), Gaps = 15/121 (12%)
Query: 747 DVDECAAIPGLCAPGR-------FRC-VCGPGYRPAGEV-CADVDECAVRPPPC-DQLCH 796
DVDEC P +C G FRC C GYR C D+DEC + P C D+ C
Sbjct: 631 DVDECLR-PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDEC-LNPSTCPDEQCV 688
Query: 797 NTDGSYDCL-CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
N+ GSY C+ C G+ C DVDEC CSN EGSY CSC GY +
Sbjct: 689 NSPGSYQCVPCTEGFR--GWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTP 746
Query: 856 D 856
D
Sbjct: 747 D 747
Score = 75.8 bits (178), Expect = 6e-13
Identities = 61/197 (30%), Positives = 84/197 (42%), Gaps = 24/197 (12%)
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWG-RYCERCPAPDSAEF---MRICQGGMGR 420
C+ E +C +A P + +CC + G +WG C++CP S M C G R
Sbjct: 233 CFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKR 292
Query: 421 PNLT--QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRI 478
N T QD++EC+++ VC G C+NT GS+RC C G+ P SCV DP +
Sbjct: 293 VNNTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVP------DPPV 345
Query: 479 CG--NGTCSN-TRGGYECQCSPGFTQGPDQTCVDVDECAEGRA---SCTFRCHNTAGSFR 532
G C G +C P Q C C+ G+A C +F+
Sbjct: 346 ISEEKGPCYRLVSSGRQCM-HPLSVHLTKQLCC----CSVGKAWGPHCEKCPLPGTAAFK 400
Query: 533 CTCPYGYAVAADGVHCR 549
CP G GVH R
Sbjct: 401 EICPGGMGYTVSGVHRR 417
Score = 67.7 bits (158), Expect = 2e-10
Identities = 48/166 (28%), Positives = 67/166 (40%), Gaps = 31/166 (18%)
Query: 6 EDQSCAGAVGVPQTKYL-CCCSVGHAWGAPCEACPPRGSPAHTALCG------EKP---- 54
++ C+ + QT Y CCC G AWG C CP + S + LC +P
Sbjct: 1206 DEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRD 1265
Query: 55 --GEYINPVTNETKP---------------IDECDIMPQLCKPGTCHDTPTGFQCGCDHG 97
++ T E P +EC I+ C+ G C G+ C C G
Sbjct: 1266 ALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGIL-NGCENGRCVRVQEGYTCDCFDG 1324
Query: 98 YEHDNTSHLCRDVDECSW--GRPPCRGMAQCVNLPGAFECRCPPGY 141
Y D C DV+EC R A+C+N G+++C C PGY
Sbjct: 1325 YHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1370
Score = 62.1 bits (144), Expect = 8e-09
Identities = 34/103 (33%), Positives = 49/103 (47%), Gaps = 4/103 (3%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC-RCPP 139
G C G QCG + C SWG C+ + + G + C P
Sbjct: 231 GRCFQETIGSQCG--KALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLP 288
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY 182
GY+ + C+D++EC Q +C +G+C NT+GSYRC CK G+
Sbjct: 289 GYKRVNNTF-CQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
Score = 60.5 bits (140), Expect = 2e-08
Identities = 44/129 (34%), Positives = 59/129 (45%), Gaps = 10/129 (7%)
Query: 165 GDC-RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAY----LCHCD 219
G C + TIGS + PG + +E+ C V S C+ C P + + C
Sbjct: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGT-SWGFNKCQK--CPKKPSYHGYNQMMECL 287
Query: 220 DGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDEC 278
G+K N C D+NEC+ G VC NG C NT+GS+RC C G+ +C D
Sbjct: 288 PGYKRVNNTFCQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVI 346
Query: 279 DELPHPCGR 287
E PC R
Sbjct: 347 SEEKGPCYR 355
Score = 59.3 bits (137), Expect = 6e-08
Identities = 30/79 (37%), Positives = 38/79 (48%), Gaps = 7/79 (8%)
Query: 565 CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED---LCSGGVCINTDGSFLCD 621
C V Y C C +GY +A C D+NEC+E + LC CINTDGS+ C
Sbjct: 1310 CVRVQEGYTCDCFDGYHLDTAKM----TCVDVNECDELNNRMSLCKNAKCINTDGSYKCL 1365
Query: 622 CDAGFEPSEDGTDCIDRRT 640
C G+ PS+ C T
Sbjct: 1366 CLPGYVPSDKPNYCTPLNT 1384
Score = 58.8 bits (136), Expect = 8e-08
Identities = 34/93 (36%), Positives = 42/93 (45%), Gaps = 10/93 (10%)
Query: 765 CVCGPGYRPAGEVCA--------DVDECAVRPPP-CDQ-LCHNTDGSYDCLCRTGYELDE 814
C G G+ PAGE + D DEC + C C NT Y+C C+ G D
Sbjct: 1075 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDP 1134
Query: 815 DGANCRDVDECERDTHTCQQICSNTEGSYECSC 847
C D+DEC+ + C NTEGSY C C
Sbjct: 1135 VKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFC 1167
Score = 53.2 bits (122), Expect = 4e-06
Identities = 25/61 (40%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Query: 8 QSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKP 67
+ C + V TK LCCCSVG AWG CE CP G+ A +C G ++ V + +P
Sbjct: 361 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGV-HRRRP 419
Query: 68 I 68
I
Sbjct: 420 I 420
Score = 50.4 bits (115), Expect = 3e-05
Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 4/74 (5%)
Query: 782 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTH---TCQQI-CS 837
+EC + + C Y C C GY LD C DV+EC+ + C+ C
Sbjct: 1297 EECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCI 1356
Query: 838 NTEGSYECSCEDGY 851
NT+GSY+C C GY
Sbjct: 1357 NTDGSYKCLCLPGY 1370
Score = 48.8 bits (111), Expect = 8e-05
Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCI 636
PE +++ + +INEC D+C G CIN + C C G+ SE C+
Sbjct: 529 PEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCV 588
Query: 637 DRRTGTCYRSLVS-GRCE 653
D T + L S GRCE
Sbjct: 589 DIDECTQVQHLCSQGRCE 606
Score = 45.6 bits (103), Expect = 8e-04
Identities = 42/164 (25%), Positives = 64/164 (39%), Gaps = 13/164 (7%)
Query: 23 CCCSVGHAWGA-PCEACPPRGS-PAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKP 80
CC +VG +WG C+ CP + S + + PG Y + I+EC + +C
Sbjct: 255 CCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPG-YKRVNNTFCQDINECQLQG-VCPN 312
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMA----QCVNLPGAF-- 133
G C +T ++C C G+ D T C D S + PC + QC++
Sbjct: 313 GECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLT 372
Query: 134 --ECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYR 175
C C G P ++C + IC G G +R
Sbjct: 373 KQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHR 416
Score = 42.7 bits (96), Expect = 0.005
Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 767 CGPGYRPAGEV-CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
C PGY+ C D++EC ++ + C NT GSY C C+ G+ D ++C
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
Score = 38.3 bits (85), Expect = 0.11
Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 535 CPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
C GY + C+DI+EC Q VCP+ C N +GSY C C G+
Sbjct: 286 CLPGYK-RVNNTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGF 330
Score = 37.1 bits (82), Expect = 0.27
Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C GY+ + C+D++EC+ C NT GSY C+C+ G+
Sbjct: 286 CLPGYKR-VNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
>AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth
factor-beta binding protein-1S protein.
Length = 1394
Score = 377 bits (928), Expect = e-104
Identities = 248/726 (34%), Positives = 330/726 (45%), Gaps = 92/726 (12%)
Query: 152 DVDECG-DQRICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCE 208
+++EC + IC G C N Y C C GY E C D+DEC++ + +C G CE
Sbjct: 546 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 605
Query: 209 NLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCE-CAPGYTLT 266
N G++LC C GF A +C+DV+EC VC G C NTVG+FRCE C GY +T
Sbjct: 606 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPD-VCGEGHCVNTVGAFRCEYCDSGYRMT 664
Query: 267 ADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC-SCGAGWKLVGRRCVDRDECKELP 325
GR C D+DEC P C + C N+ G Y+C C G++ +C+D DEC E P
Sbjct: 665 QRGR-CEDIDECLN-PSTCPDE---QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE-P 718
Query: 326 YVCAGGECRNFNGGYVCECPAGWRFDKTAAVC--VDERKE--LCYDEWEAGRCHRARPLQ 381
VCA G+C N G Y+C C G+ C +DE ++ LC + G+C
Sbjct: 719 NVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVN----GQCKNTE--- 771
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
C C +G ++C +D+DEC+ R +C G+
Sbjct: 772 -GSFRCTCGQGYQLSAAKDQC----------------------EDIDECQHR-HLCAHGQ 807
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
C NT+GSF+C C GY + G C D +EC D +C G C NT G Y+C C GF
Sbjct: 808 CRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL 867
Query: 502 GPDQTCVDVDECAE-GRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRV 560
++TC D++EC G C NT GSF C C G++++ADG C DIDECV
Sbjct: 868 DDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVC 927
Query: 561 CPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFL 619
H C+N GS+ C C +G++ APQD + C D+NECE +C C N +GSFL
Sbjct: 928 DSHGFCDNTAGSFRCLCYQGFQ---APQDGQ-GCVDVNECELLSGVCGEAFCENVEGSFL 983
Query: 620 CDC-DAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXG 678
C C D E S C RT T L +P+
Sbjct: 984 CVCADENQEYSPMTGQC-RSRTST---DLDVDVDQPK-EEKKECYYNLNDASLCDNVLAP 1038
Query: 679 HVTKAQCCCTLGAAWGSECEL--CPAPGSPARLDLC-TAVNLTPXXXXXXXXXXXXXXXX 735
+VTK +CCCT GA WG CE+ CP G+ ++C P
Sbjct: 1039 NVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGG------ 1092
Query: 736 XXXXXXLDVFADVDECAAI------PGLCAPGR--FRCVCGPG--YRPAGEVCADVDECA 785
+ + D DEC G C R + C C G Y P C D+DEC
Sbjct: 1093 -------ENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ 1145
Query: 786 VRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECER--DTHTCQQIC-SNTE 840
P C D C NT+GSY+C C LD C R + E+ +T Q +C +
Sbjct: 1146 -DPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLS 1204
Query: 841 GSYECS 846
Y CS
Sbjct: 1205 DEYVCS 1210
Score = 329 bits (809), Expect = 2e-89
Identities = 268/842 (31%), Positives = 346/842 (41%), Gaps = 118/842 (14%)
Query: 46 HTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSH 105
+T +C E G + + IDEC + LC G C +T F C C G+
Sbjct: 569 YTCICYE--GYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGT 626
Query: 106 LCRDVDECSWGRPPCRGMAQCVNLPGAFECR-CPPGYRLTPSLDECEDVDECGDQRICDH 164
C DVDEC RP G CVN GAF C C GYR+T CED+DEC + C
Sbjct: 627 NCIDVDECL--RPDVCGEGHCVNTVGAFRCEYCDSGYRMTQR-GRCEDIDECLNPSTCPD 683
Query: 165 GDCRNTIGSYRC-ECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK 223
C N+ GSY+C C G+ C DVDEC P VC NG C NL G+Y+C C G+
Sbjct: 684 EQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN-VCANGDCSNLEGSYMCSCHKGYT 742
Query: 224 AGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELP 282
P++ C D++EC++G + C NG+C+NT GSFRC C GY L+A C D+DEC
Sbjct: 743 RTPDHKHCRDIDECQQGNL-CVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHR- 800
Query: 283 HPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGECRNFNGGY 340
H C C NT G ++C C G++ +G C D +EC E VC G+C N G Y
Sbjct: 801 HLCAHG---QCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSY 857
Query: 341 VCECPAGWRFDKTAAVCVD----ERKELCYDEWEAGRCHRARPLQLARPECCCSEG---A 393
C CP G++ D C D E LC + G C C C +G +
Sbjct: 858 DCTCPDGFQLDDNKT-CQDINECEHPGLCGPQ---GECLNTE----GSFHCVCQQGFSIS 909
Query: 394 AWGRYCE---RC---PAPDS--------AEFMRICQGGMGRPNLTQ---DLDECRVRPDV 436
A GR CE C DS F +C G P Q D++EC + V
Sbjct: 910 ADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGV 969
Query: 437 CVGGRCVNTDGSFRCECPD-GYVLAPDGLSC---------VDAD-------ECAL---DP 476
C C N +GSF C C D +P C VD D EC D
Sbjct: 970 CGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDA 1029
Query: 477 RICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAE-GRASCTFRCHNTAGSFRCTC 535
+C N N EC C+ G G + C ++ C G A T C G
Sbjct: 1030 SLCDNVLAPNVTK-QECCCTSGAGWGDN--C-EIFPCPVLGTAEFTEMCPKGKGFV---- 1081
Query: 536 PYGYAVA-ADGVHCRDIDECVQ-EPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENA 592
P G + + A G + +D DEC+ +C + C N Y C C +G + +
Sbjct: 1082 PAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQG----TYYDPVKLQ 1137
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRC 652
C D++EC++ C G C+NT+GS+ C C P D ++R C R S
Sbjct: 1138 CFDMDECQDPSS-CIDGQCVNTEGSYNCFCT---HPMV--LDASEKR---CIRPAESNEQ 1188
Query: 653 --EPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLD 710
E + T +CCC G AWG +C LCP S
Sbjct: 1189 IEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQ 1248
Query: 711 LC---TAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFAD------VDECAAIPGLCAPG 761
LC P D F + +EC + G C G
Sbjct: 1249 LCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-CENG 1307
Query: 762 R-------FRCVCGPGYR--PAGEVCADVDECAV---RPPPC-DQLCHNTDGSYDCLCRT 808
R + C C GY A C DV+EC R C + C NTDGSY CLC
Sbjct: 1308 RCVRVQEGYTCDCLDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLP 1367
Query: 809 GY 810
GY
Sbjct: 1368 GY 1369
Score = 319 bits (784), Expect = 2e-86
Identities = 175/476 (36%), Positives = 236/476 (49%), Gaps = 44/476 (9%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
I+EC + P +C G C + P + C C GY C D+DEC+ + C +C
Sbjct: 547 INECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC-SQGRCE 605
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCE-CKPGYTL-R 185
N G+F C CP G+ + C DVDEC +C G C NT+G++RCE C GY + +
Sbjct: 606 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 665
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLC-HCDDGFKAGPNNDCVDVNECREGGMVCR 244
C D+DEC P C + C N PG+Y C C +GF+ G N C+DV+EC E VC
Sbjct: 666 RGRCEDIDECLNP-STCPDEQCVNSPGSYQCVPCTEGFR-GWNGQCLDVDECLEPN-VCA 722
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
NG C N GS+ C C GYT T D ++CRD+DEC + + C N C NT G + C+C
Sbjct: 723 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQ-GNLC---VNGQCKNTEGSFRCTC 778
Query: 305 GAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
G G++L + C D DEC+ ++CA G+CRN G + C C G+R C D +
Sbjct: 779 GQGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE 837
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPN 422
C ++ C R + A G Y CP + + C
Sbjct: 838 --CLEDKSV--CQRGDCINTA------------GSYDCTCPDGFQLDDNKTC-------- 873
Query: 423 LTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGN 481
QD++EC P +C G C+NT+GSF C C G+ ++ DG +C D DEC + +
Sbjct: 874 --QDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSH 930
Query: 482 GTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASC-TFRCHNTAGSFRCTC 535
G C NT G + C C GF D Q CVDV+EC C C N GSF C C
Sbjct: 931 GFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 986
Score = 174 bits (423), Expect = 1e-42
Identities = 154/536 (28%), Positives = 216/536 (40%), Gaps = 69/536 (12%)
Query: 63 NET-KPIDECDIMPQLCKP-GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
N+T + I+EC+ P LC P G C +T F C C G+ C D+DEC C
Sbjct: 870 NKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECV-NNTVC 927
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCEC- 178
C N G+F C C G++ C DV+EC +C C N GS+ C C
Sbjct: 928 DSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCA 987
Query: 179 --KPGYTLRENVCR---------DVDECSRPRPVCRNGT-----CENLPGAYL----CHC 218
Y+ CR DVD+ + C C+N+ + C C
Sbjct: 988 DENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCC 1047
Query: 219 DDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC 278
G AG ++C ++ C G C G A + A G N +D DEC
Sbjct: 1048 TSG--AGWGDNC-EIFPCPVLGTAEFTEMCPKGKGFVP---AGESSSEAGGENYKDADEC 1101
Query: 279 DELPHPCGRDGNPSCTNTNGGYECSCGAG--WKLVGRRCVDRDECKELPYVCAGGECRNF 336
++G C NT GYEC C G + V +C D DEC++ P C G+C N
Sbjct: 1102 LLFGQEICKNG--FCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQD-PSSCIDGQCVNT 1158
Query: 337 NGGYVCECPAGWRFDKTAAVCV------------DERKELCYDEWEAGRCHRARPL---Q 381
G Y C C D + C+ D ++LC++ + +RPL Q
Sbjct: 1159 EGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHL-SDEYVCSRPLVGKQ 1217
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
ECCC G AWG C CP DS ++ ++C N+ D V
Sbjct: 1218 TTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC-------NIPVTGRRQPYGRDALVDFS 1270
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGF-T 500
T + D ++ + + A+EC + C NG C + GY C C G+
Sbjct: 1271 EQYTPEADPYFIQDRFL---NSFEELQAEECGI-LNGCENGRCVRVQEGYTCDCLDGYHL 1326
Query: 501 QGPDQTCVDVDECAE--GRAS-C-TFRCHNTAGSFRCTCPYGYAVAADGVHCRDID 552
TCVDV+EC E R S C +C NT GS++C C GY + +C ++
Sbjct: 1327 DTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1382
Score = 170 bits (414), Expect = 2e-41
Identities = 87/237 (36%), Positives = 117/237 (49%), Gaps = 13/237 (5%)
Query: 421 PNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG 480
P +++EC V PD+C G C+N + C C +GY + CVD DEC +C
Sbjct: 541 PTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCS 600
Query: 481 NGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCT-CPYG 538
G C NT G + C C GF + T C+DVDEC C NT G+FRC C G
Sbjct: 601 QGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSG 660
Query: 539 YAVAADGVHCRDIDECVQEPRVCP-HACENVVGSYIC-KCPEGYRRTSAPQDSENACEDI 596
Y + G C DIDEC+ P CP C N GSY C C EG+R + C D+
Sbjct: 661 YRMTQRG-RCEDIDECL-NPSTCPDEQCVNSPGSYQCVPCTEGFRGWN------GQCLDV 712
Query: 597 NECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCE 653
+EC E ++C+ G C N +GS++C C G+ + D C D V+G+C+
Sbjct: 713 DECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK 768
Score = 152 bits (369), Expect = 4e-36
Identities = 154/574 (26%), Positives = 220/574 (38%), Gaps = 70/574 (12%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPP-CRGMAQC 126
I+EC +C+ G C +T + C C G++ D+ C+D++EC P C +C
Sbjct: 835 INECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNK-TCQDINECE--HPGLCGPQGEC 891
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICD-HGDCRNTIGSYRCECKPGYTLR 185
+N G+F C C G+ ++ CED+DEC + +CD HG C NT GS+RC C G+
Sbjct: 892 LNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAP 951
Query: 186 ENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHC-DDGFKAGP-NNDC---------VD 232
++ C DV+EC VC CEN+ G++LC C D+ + P C VD
Sbjct: 952 QDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVD 1011
Query: 233 VNECREGGMVCRNGR-----CRNT----VGSFRCECAPGYTLTADGRNCRDVDECDELPH 283
V++ +E C C N V C C G G NC ++ C L
Sbjct: 1012 VDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG---AGWGDNC-EIFPCPVLGT 1067
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPY-VCAGGECRNFNGGYVC 342
+ P E S AG G D DEC +C G C N GY C
Sbjct: 1068 AEFTEMCPKGKGFVPAGESSSEAG----GENYKDADECLLFGQEICKNGFCLNTRPGYEC 1123
Query: 343 ECPAGWRFDKTAAVCVDERKELCYDEWEA--GRCHRARPLQLARPECCCSEGAAWGRYCE 400
C G +D C D + C D G+C C C+ +
Sbjct: 1124 YCKQGTYYDPVKLQCFD--MDECQDPSSCIDGQCVNTE----GSYNCFCTHPMVLDASEK 1177
Query: 401 RCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLA 460
RC P + +I + + + + L + V VG + T+ C C G
Sbjct: 1178 RCIRPAESN-EQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTE----CCCLYGEAWG 1232
Query: 461 PDGLSCV--DADECALDPRI--------CGNGTCSNTRGGYECQCSPGFTQGPDQTCVD- 509
C D+D+ A I G + Y + P F Q +
Sbjct: 1233 MQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEE 1292
Query: 510 --VDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ---EPRVCPHA 564
+EC RC + C C GY + + C D++EC + +C +A
Sbjct: 1293 LQAEECGILNGCENGRCVRVQEGYTCDCLDGYHLDTAKMTCVDVNECDELNNRMSLCKNA 1352
Query: 565 -CENVVGSYICKCPEGYRRTSAPQDSENACEDIN 597
C N GSY C C GY P D N C +N
Sbjct: 1353 KCINTDGSYKCLCLPGY----VPSDKPNYCTPLN 1382
Score = 102 bits (245), Expect = 5e-21
Identities = 48/115 (41%), Positives = 64/115 (55%), Gaps = 9/115 (7%)
Query: 747 DVDECA----AIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNT 798
D+DEC + G C G FRC CG GY+ A + C D+DEC R C NT
Sbjct: 752 DIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNT 811
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE 852
+GS+ C+C GY G +C D++EC D CQ+ C NT GSY+C+C DG++
Sbjct: 812 EGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ 866
Score = 93.5 bits (222), Expect = 3e-18
Identities = 47/115 (40%), Positives = 62/115 (53%), Gaps = 11/115 (9%)
Query: 747 DVDECAAIPGLC-------APGRFRCV-CGPGYRPAGEVCADVDECAVRPPPC-DQLCHN 797
D+DEC P C +PG ++CV C G+R C DVDEC + P C + C N
Sbjct: 671 DIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDEC-LEPNVCANGDCSN 728
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+GSY C C GY D +CRD+DEC++ C NTEGS+ C+C GY+
Sbjct: 729 LEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQ 783
Score = 93.5 bits (222), Expect = 3e-18
Identities = 49/116 (42%), Positives = 62/116 (53%), Gaps = 15/116 (12%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQ--L 794
D++EC PGLC P G F CVC G+ + G C D+DEC V CD
Sbjct: 875 DINECEH-PGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGF 932
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCED 849
C NT GS+ CLC G++ +DG C DV+ECE + C + C N EGS+ C C D
Sbjct: 933 CDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCAD 988
Score = 91.5 bits (217), Expect = 1e-17
Identities = 66/183 (36%), Positives = 82/183 (44%), Gaps = 15/183 (8%)
Query: 246 GRC-RNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
GRC + T+GS + PG + D C + PS N EC
Sbjct: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPK--KPSYHGYNQMMECL- 287
Query: 305 GAGWKLVGRR-CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV----- 358
G+K V C D +EC +L VC GEC N G Y C C G+ D T + CV
Sbjct: 288 -PGYKRVNNTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV 345
Query: 359 -DERKELCYDEWEAGR-CHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
E K CY +GR C + L + CCCS G A G +CE+CP P +A F IC G
Sbjct: 346 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKA-GPHCEKCPLPGTAAFKEICPG 404
Query: 417 GMG 419
GMG
Sbjct: 405 GMG 407
Score = 91.1 bits (216), Expect = 2e-17
Identities = 44/116 (37%), Positives = 62/116 (53%), Gaps = 11/116 (9%)
Query: 747 DVDECAAIPGLCAPG-------RFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQ-LCH 796
+++EC P +C G R+ C+C GYR + + C D+DEC C Q C
Sbjct: 546 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 605
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGY 851
NT+GS+ C+C G+ E+G NC DVDEC R + C NT G++ C C+ GY
Sbjct: 606 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGY 661
Score = 90.6 bits (215), Expect = 2e-17
Identities = 47/119 (39%), Positives = 60/119 (50%), Gaps = 12/119 (10%)
Query: 747 DVDECAAIPGLCA-------PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHN 797
DVDEC P +CA G + C C GY P + C D+DEC + C N
Sbjct: 711 DVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKN 769
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRG 855
T+GS+ C C GY+L C D+DEC+ H C C NTEGS++C C+ GY G
Sbjct: 770 TEGSFRCTCGQGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASG 827
Score = 86.2 bits (204), Expect = 4e-16
Identities = 90/310 (29%), Positives = 124/310 (40%), Gaps = 31/310 (10%)
Query: 38 CPPRGSPAHTA---LCGEKPGEYINPVTNETKPIDECDIMPQLCKP-GTCHDTPTGFQCG 93
C P+G +T C + G I+ + IDEC + +C G C +T F+C
Sbjct: 885 CGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCL 943
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPP-GYRLTPSLDECE- 151
C G++ C DV+EC C G A C N+ G+F C C +P +C
Sbjct: 944 CYQGFQAPQDGQGCVDVNECELLSGVC-GEAFCENVEGSFLCVCADENQEYSPMTGQCRS 1002
Query: 152 ----DVDECGDQRICDHGDCR-NTIGSYRCE--CKPGYTLRENVCRDV----DECSR-PR 199
D+D DQ + +C N + C+ P T +E C D C P
Sbjct: 1003 RTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPC 1062
Query: 200 PVCRNGT-CENLPGA--YLCHCDDGFKAGPNNDCVDVNECREGGM-VCRNGRCRNTVGSF 255
PV E P ++ + +AG N D +EC G +C+NG C NT +
Sbjct: 1063 PVLGTAEFTEMCPKGKGFVPAGESSSEAGGEN-YKDADECLLFGQEICKNGFCLNTRPGY 1121
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--R 313
C C G C D+DEC + P C DG C NT G Y C C L +
Sbjct: 1122 ECYCKQGTYYDPVKLQCFDMDECQD-PSSC-IDG--QCVNTEGSYNCFCTHPMVLDASEK 1177
Query: 314 RCVDRDECKE 323
RC+ E E
Sbjct: 1178 RCIRPAESNE 1187
Score = 83.4 bits (197), Expect = 3e-15
Identities = 58/167 (34%), Positives = 73/167 (43%), Gaps = 12/167 (7%)
Query: 3 WNEEDQSCAGAVGVPQ-TKYLCCCSVGHAWGAPCEA--CPPRGSPAHTALC----GEKP- 54
+N D S V P TK CCC+ G WG CE CP G+ T +C G P
Sbjct: 1024 YNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPA 1083
Query: 55 GEYINPVTNET-KPIDECDIMPQ-LCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDE 112
GE + E K DEC + Q +CK G C +T G++C C G +D C D+DE
Sbjct: 1084 GESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDE 1143
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQ 159
C P QCVN G++ C C L S C E +Q
Sbjct: 1144 CQ--DPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQ 1188
Score = 83.0 bits (196), Expect = 4e-15
Identities = 42/127 (33%), Positives = 63/127 (49%), Gaps = 16/127 (12%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYR-PAGEVCADVDECAVRPPPCDQL--CH 796
D++EC +C G + C C G++ + C D++EC P C C
Sbjct: 834 DINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECL 892
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE-- 852
NT+GS+ C+C+ G+ + DG C D+DEC +T C C NT GS+ C C G++
Sbjct: 893 NTEGSFHCVCQQGFSISADGRTCEDIDECVNNT-VCDSHGFCDNTAGSFRCLCYQGFQAP 951
Query: 853 KRGDACV 859
+ G CV
Sbjct: 952 QDGQGCV 958
Score = 81.0 bits (191), Expect = 2e-14
Identities = 50/121 (41%), Positives = 58/121 (47%), Gaps = 15/121 (12%)
Query: 747 DVDECAAIPGLCAPGR-------FRC-VCGPGYRPAGEV-CADVDECAVRPPPC-DQLCH 796
DVDEC P +C G FRC C GYR C D+DEC + P C D+ C
Sbjct: 630 DVDECLR-PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDEC-LNPSTCPDEQCV 687
Query: 797 NTDGSYDCL-CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
N+ GSY C+ C G+ C DVDEC CSN EGSY CSC GY +
Sbjct: 688 NSPGSYQCVPCTEGFR--GWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTP 745
Query: 856 D 856
D
Sbjct: 746 D 746
Score = 79.0 bits (186), Expect = 7e-14
Identities = 54/182 (29%), Positives = 77/182 (42%), Gaps = 22/182 (12%)
Query: 6 EDQSCAGAVGVPQTKYL-CCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNE 64
++ C+ + QT Y CCC G AWG C CP + S + LC PVT
Sbjct: 1205 DEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCN-------IPVTGR 1257
Query: 65 TKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+P D + + T P Q + +E + + C ++ C GR
Sbjct: 1258 RQPYGR-DALVDFSEQYTPEADPYFIQDRFLNSFE-ELQAEECGILNGCENGR------- 1308
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECEDVDECGD----QRICDHGDCRNTIGSYRCECKP 180
CV + + C C GY L + C DV+EC + +C + C NT GSY+C C P
Sbjct: 1309 -CVRVQEGYTCDCLDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLP 1367
Query: 181 GY 182
GY
Sbjct: 1368 GY 1369
Score = 77.4 bits (182), Expect = 2e-13
Identities = 59/194 (30%), Positives = 81/194 (41%), Gaps = 19/194 (9%)
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWG-RYCERCPAPDSAEF---MRICQGGMGR 420
C+ E +C +A P + +CC + G +WG C++CP S M C G R
Sbjct: 233 CFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKR 292
Query: 421 PNLT--QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRI 478
N T QD++EC+++ VC G C+NT GS+RC C G+ P SCV DP +
Sbjct: 293 VNNTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVP------DPPV 345
Query: 479 CG--NGTCSN-TRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
G C G +C C V + C TA +F+ C
Sbjct: 346 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAGPHCEKCPL--PGTA-AFKEIC 402
Query: 536 PYGYAVAADGVHCR 549
P G GVH R
Sbjct: 403 PGGMGYTVSGVHRR 416
Score = 77.0 bits (181), Expect = 3e-13
Identities = 49/144 (34%), Positives = 65/144 (45%), Gaps = 32/144 (22%)
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTD 634
+C GY+R + C+DINEC+ Q +C G C+NT GS+ C C GF P +
Sbjct: 285 ECLPGYKRVN-----NTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSS 338
Query: 635 C------IDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCT 688
C I G CYR + SGR H+TK CCC+
Sbjct: 339 CVPDPPVISEEKGPCYRLVSSGR-------------------QCMHPLSVHLTKQLCCCS 379
Query: 689 LGAAWGSECELCPAPGSPARLDLC 712
+G A G CE CP PG+ A ++C
Sbjct: 380 VGKA-GPHCEKCPLPGTAAFKEIC 402
Score = 62.1 bits (144), Expect = 8e-09
Identities = 34/103 (33%), Positives = 49/103 (47%), Gaps = 4/103 (3%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC-RCPP 139
G C G QCG + C SWG C+ + + G + C P
Sbjct: 231 GRCFQETIGSQCG--KALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLP 288
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY 182
GY+ + C+D++EC Q +C +G+C NT+GSYRC CK G+
Sbjct: 289 GYKRVNNTF-CQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
Score = 60.5 bits (140), Expect = 2e-08
Identities = 44/129 (34%), Positives = 59/129 (45%), Gaps = 10/129 (7%)
Query: 165 GDC-RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAY----LCHCD 219
G C + TIGS + PG + +E+ C V S C+ C P + + C
Sbjct: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGT-SWGFNKCQK--CPKKPSYHGYNQMMECL 287
Query: 220 DGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDEC 278
G+K N C D+NEC+ G VC NG C NT+GS+RC C G+ +C D
Sbjct: 288 PGYKRVNNTFCQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVI 346
Query: 279 DELPHPCGR 287
E PC R
Sbjct: 347 SEEKGPCYR 355
Score = 59.7 bits (138), Expect = 4e-08
Identities = 30/79 (37%), Positives = 38/79 (48%), Gaps = 7/79 (8%)
Query: 565 CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED---LCSGGVCINTDGSFLCD 621
C V Y C C +GY +A C D+NEC+E + LC CINTDGS+ C
Sbjct: 1309 CVRVQEGYTCDCLDGYHLDTAKM----TCVDVNECDELNNRMSLCKNAKCINTDGSYKCL 1364
Query: 622 CDAGFEPSEDGTDCIDRRT 640
C G+ PS+ C T
Sbjct: 1365 CLPGYVPSDKPNYCTPLNT 1383
Score = 58.8 bits (136), Expect = 8e-08
Identities = 34/93 (36%), Positives = 42/93 (45%), Gaps = 10/93 (10%)
Query: 765 CVCGPGYRPAGEVCA--------DVDECAVRPPP-CDQ-LCHNTDGSYDCLCRTGYELDE 814
C G G+ PAGE + D DEC + C C NT Y+C C+ G D
Sbjct: 1074 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDP 1133
Query: 815 DGANCRDVDECERDTHTCQQICSNTEGSYECSC 847
C D+DEC+ + C NTEGSY C C
Sbjct: 1134 VKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFC 1166
Score = 50.8 bits (116), Expect = 2e-05
Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 4/74 (5%)
Query: 782 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTH---TCQQI-CS 837
+EC + + C Y C C GY LD C DV+EC+ + C+ C
Sbjct: 1296 EECGILNGCENGRCVRVQEGYTCDCLDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCI 1355
Query: 838 NTEGSYECSCEDGY 851
NT+GSY+C C GY
Sbjct: 1356 NTDGSYKCLCLPGY 1369
Score = 48.8 bits (111), Expect = 8e-05
Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCI 636
PE +++ + +INEC D+C G CIN + C C G+ SE C+
Sbjct: 528 PEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCV 587
Query: 637 DRRTGTCYRSLVS-GRCE 653
D T + L S GRCE
Sbjct: 588 DIDECTQVQHLCSQGRCE 605
Score = 44.4 bits (100), Expect = 0.002
Identities = 24/61 (39%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 8 QSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKP 67
+ C + V TK LCCCSVG A G CE CP G+ A +C G ++ V + +P
Sbjct: 361 RQCMHPLSVHLTKQLCCCSVGKA-GPHCEKCPLPGTAAFKEICPGGMGYTVSGV-HRRRP 418
Query: 68 I 68
I
Sbjct: 419 I 419
Score = 44.0 bits (99), Expect = 0.002
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 5/101 (4%)
Query: 23 CCCSVGHAWGA-PCEACPPRGS-PAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKP 80
CC +VG +WG C+ CP + S + + PG Y + I+EC + +C
Sbjct: 255 CCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPG-YKRVNNTFCQDINECQLQG-VCPN 312
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPC 120
G C +T ++C C G+ D T C D S + PC
Sbjct: 313 GECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPC 353
Score = 42.7 bits (96), Expect = 0.005
Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 767 CGPGYRPAGEV-CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
C PGY+ C D++EC ++ + C NT GSY C C+ G+ D ++C
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
Score = 38.3 bits (85), Expect = 0.11
Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 535 CPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
C GY + C+DI+EC Q VCP+ C N +GSY C C G+
Sbjct: 286 CLPGYK-RVNNTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGF 330
Score = 37.1 bits (82), Expect = 0.27
Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 3/57 (5%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDEC 150
C GY+ N + C+D++EC + C +C+N G++ C C G+ P+ C
Sbjct: 286 CLPGYKRVNNT-FCQDINECQL-QGVCPN-GECLNTMGSYRCTCKIGFGPDPTFSSC 339
Score = 37.1 bits (82), Expect = 0.27
Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C GY+ + C+D++EC+ C NT GSY C+C+ G+
Sbjct: 286 CLPGYKR-VNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
>AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming growth
factor beta binding protein 1 isoform LTBP-1S varian
protein.
Length = 1348
Score = 377 bits (928), Expect = e-104
Identities = 248/726 (34%), Positives = 330/726 (45%), Gaps = 92/726 (12%)
Query: 152 DVDECG-DQRICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCE 208
+++EC + IC G C N Y C C GY E C D+DEC++ + +C G CE
Sbjct: 500 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 559
Query: 209 NLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCE-CAPGYTLT 266
N G++LC C GF A +C+DV+EC VC G C NTVG+FRCE C GY +T
Sbjct: 560 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPD-VCGEGHCVNTVGAFRCEYCDSGYRMT 618
Query: 267 ADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC-SCGAGWKLVGRRCVDRDECKELP 325
GR C D+DEC P C + C N+ G Y+C C G++ +C+D DEC E P
Sbjct: 619 QRGR-CEDIDECLN-PSTCPDE---QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE-P 672
Query: 326 YVCAGGECRNFNGGYVCECPAGWRFDKTAAVC--VDERKE--LCYDEWEAGRCHRARPLQ 381
VCA G+C N G Y+C C G+ C +DE ++ LC + G+C
Sbjct: 673 NVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVN----GQCKNTE--- 725
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
C C +G ++C +D+DEC+ R +C G+
Sbjct: 726 -GSFRCTCGQGYQLSAAKDQC----------------------EDIDECQHR-HLCAHGQ 761
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
C NT+GSF+C C GY + G C D +EC D +C G C NT G Y+C C GF
Sbjct: 762 CRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL 821
Query: 502 GPDQTCVDVDECAE-GRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRV 560
++TC D++EC G C NT GSF C C G++++ADG C DIDECV
Sbjct: 822 DDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVC 881
Query: 561 CPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFL 619
H C+N GS+ C C +G++ APQD + C D+NECE +C C N +GSFL
Sbjct: 882 DSHGFCDNTAGSFRCLCYQGFQ---APQDGQ-GCVDVNECELLSGVCGEAFCENVEGSFL 937
Query: 620 CDC-DAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXG 678
C C D E S C RT T L +P+
Sbjct: 938 CVCADENQEYSPMTGQC-RSRTST---DLDVDVDQPK-EEKKECYYNLNDASLCDNVLAP 992
Query: 679 HVTKAQCCCTLGAAWGSECEL--CPAPGSPARLDLC-TAVNLTPXXXXXXXXXXXXXXXX 735
+VTK +CCCT GA WG CE+ CP G+ ++C P
Sbjct: 993 NVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGG------ 1046
Query: 736 XXXXXXLDVFADVDECAAI------PGLCAPGR--FRCVCGPG--YRPAGEVCADVDECA 785
+ + D DEC G C R + C C G Y P C D+DEC
Sbjct: 1047 -------ENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ 1099
Query: 786 VRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECER--DTHTCQQIC-SNTE 840
P C D C NT+GSY+C C LD C R + E+ +T Q +C +
Sbjct: 1100 -DPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLS 1158
Query: 841 GSYECS 846
Y CS
Sbjct: 1159 DEYVCS 1164
Score = 330 bits (810), Expect = 2e-89
Identities = 268/842 (31%), Positives = 345/842 (40%), Gaps = 118/842 (14%)
Query: 46 HTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSH 105
+T +C E G + + IDEC + LC G C +T F C C G+
Sbjct: 523 YTCICYE--GYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGT 580
Query: 106 LCRDVDECSWGRPPCRGMAQCVNLPGAFECR-CPPGYRLTPSLDECEDVDECGDQRICDH 164
C DVDEC RP G CVN GAF C C GYR+T CED+DEC + C
Sbjct: 581 NCIDVDECL--RPDVCGEGHCVNTVGAFRCEYCDSGYRMTQR-GRCEDIDECLNPSTCPD 637
Query: 165 GDCRNTIGSYRC-ECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK 223
C N+ GSY+C C G+ C DVDEC P VC NG C NL G+Y+C C G+
Sbjct: 638 EQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN-VCANGDCSNLEGSYMCSCHKGYT 696
Query: 224 AGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELP 282
P++ C D++EC++G + C NG+C+NT GSFRC C GY L+A C D+DEC
Sbjct: 697 RTPDHKHCRDIDECQQGNL-CVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHR- 754
Query: 283 HPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGECRNFNGGY 340
H C C NT G ++C C G++ +G C D +EC E VC G+C N G Y
Sbjct: 755 HLCAHG---QCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSY 811
Query: 341 VCECPAGWRFDKTAAVCVD----ERKELCYDEWEAGRCHRARPLQLARPECCCSEG---A 393
C CP G++ D C D E LC + G C C C +G +
Sbjct: 812 DCTCPDGFQLDDNKT-CQDINECEHPGLCGPQ---GECLNTE----GSFHCVCQQGFSIS 863
Query: 394 AWGRYCE---RC---PAPDS--------AEFMRICQGGMGRPNLTQ---DLDECRVRPDV 436
A GR CE C DS F +C G P Q D++EC + V
Sbjct: 864 ADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGV 923
Query: 437 CVGGRCVNTDGSFRCECPD-GYVLAPDGLSC---------VDAD-------ECAL---DP 476
C C N +GSF C C D +P C VD D EC D
Sbjct: 924 CGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDA 983
Query: 477 RICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAE-GRASCTFRCHNTAGSFRCTC 535
+C N N EC C+ G G + C ++ C G A T C G
Sbjct: 984 SLCDNVLAPNVTK-QECCCTSGAGWGDN--C-EIFPCPVLGTAEFTEMCPKGKGFV---- 1035
Query: 536 PYGYAVA-ADGVHCRDIDECVQ-EPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENA 592
P G + + A G + +D DEC+ +C + C N Y C C +G + +
Sbjct: 1036 PAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQG----TYYDPVKLQ 1091
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRC 652
C D++EC++ C G C+NT+GS+ C C P D ++R C R S
Sbjct: 1092 CFDMDECQDPSS-CIDGQCVNTEGSYNCFCT---HPMV--LDASEKR---CIRPAESNEQ 1142
Query: 653 --EPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLD 710
E + T +CCC G AWG +C LCP S
Sbjct: 1143 IEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQ 1202
Query: 711 LCTAV---NLTPXXXXXXXXXXXXXXXXXXXXXXLDVFAD------VDECAAIPGLCAPG 761
LC P D F + +EC + G C G
Sbjct: 1203 LCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-CENG 1261
Query: 762 R-------FRCVCGPGYR--PAGEVCADVDECAV---RPPPCDQL-CHNTDGSYDCLCRT 808
R + C C GY A C DV+EC R C C NTDGSY CLC
Sbjct: 1262 RCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLP 1321
Query: 809 GY 810
GY
Sbjct: 1322 GY 1323
Score = 319 bits (784), Expect = 2e-86
Identities = 175/476 (36%), Positives = 236/476 (49%), Gaps = 44/476 (9%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
I+EC + P +C G C + P + C C GY C D+DEC+ + C +C
Sbjct: 501 INECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC-SQGRCE 559
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCE-CKPGYTL-R 185
N G+F C CP G+ + C DVDEC +C G C NT+G++RCE C GY + +
Sbjct: 560 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 619
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLC-HCDDGFKAGPNNDCVDVNECREGGMVCR 244
C D+DEC P C + C N PG+Y C C +GF+ G N C+DV+EC E VC
Sbjct: 620 RGRCEDIDECLNP-STCPDEQCVNSPGSYQCVPCTEGFR-GWNGQCLDVDECLEPN-VCA 676
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
NG C N GS+ C C GYT T D ++CRD+DEC + + C N C NT G + C+C
Sbjct: 677 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQ-GNLC---VNGQCKNTEGSFRCTC 732
Query: 305 GAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
G G++L + C D DEC+ ++CA G+CRN G + C C G+R C D +
Sbjct: 733 GQGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE 791
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPN 422
C ++ C R + A G Y CP + + C
Sbjct: 792 --CLEDKSV--CQRGDCINTA------------GSYDCTCPDGFQLDDNKTC-------- 827
Query: 423 LTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGN 481
QD++EC P +C G C+NT+GSF C C G+ ++ DG +C D DEC + +
Sbjct: 828 --QDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSH 884
Query: 482 GTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASC-TFRCHNTAGSFRCTC 535
G C NT G + C C GF D Q CVDV+EC C C N GSF C C
Sbjct: 885 GFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 940
Score = 174 bits (423), Expect = 1e-42
Identities = 154/536 (28%), Positives = 216/536 (40%), Gaps = 69/536 (12%)
Query: 63 NET-KPIDECDIMPQLCKP-GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
N+T + I+EC+ P LC P G C +T F C C G+ C D+DEC C
Sbjct: 824 NKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECV-NNTVC 881
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCEC- 178
C N G+F C C G++ C DV+EC +C C N GS+ C C
Sbjct: 882 DSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCA 941
Query: 179 --KPGYTLRENVCR---------DVDECSRPRPVCRNGT-----CENLPGAYL----CHC 218
Y+ CR DVD+ + C C+N+ + C C
Sbjct: 942 DENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCC 1001
Query: 219 DDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC 278
G AG ++C ++ C G C G A + A G N +D DEC
Sbjct: 1002 TSG--AGWGDNC-EIFPCPVLGTAEFTEMCPKGKGFVP---AGESSSEAGGENYKDADEC 1055
Query: 279 DELPHPCGRDGNPSCTNTNGGYECSCGAG--WKLVGRRCVDRDECKELPYVCAGGECRNF 336
++G C NT GYEC C G + V +C D DEC++ P C G+C N
Sbjct: 1056 LLFGQEICKNG--FCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQD-PSSCIDGQCVNT 1112
Query: 337 NGGYVCECPAGWRFDKTAAVCV------------DERKELCYDEWEAGRCHRARPL---Q 381
G Y C C D + C+ D ++LC++ + +RPL Q
Sbjct: 1113 EGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHL-SDEYVCSRPLVGKQ 1171
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
ECCC G AWG C CP DS ++ ++C N+ D V
Sbjct: 1172 TTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC-------NIPVTGRRQPYGRDALVDFS 1224
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGF-T 500
T + D ++ + + A+EC + C NG C + GY C C G+
Sbjct: 1225 EQYTPEADPYFIQDRFL---NSFEELQAEECGI-LNGCENGRCVRVQEGYTCDCFDGYHL 1280
Query: 501 QGPDQTCVDVDECAE--GRAS-C-TFRCHNTAGSFRCTCPYGYAVAADGVHCRDID 552
TCVDV+EC E R S C +C NT GS++C C GY + +C ++
Sbjct: 1281 DTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1336
Score = 170 bits (414), Expect = 2e-41
Identities = 87/237 (36%), Positives = 117/237 (49%), Gaps = 13/237 (5%)
Query: 421 PNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG 480
P +++EC V PD+C G C+N + C C +GY + CVD DEC +C
Sbjct: 495 PTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCS 554
Query: 481 NGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCT-CPYG 538
G C NT G + C C GF + T C+DVDEC C NT G+FRC C G
Sbjct: 555 QGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSG 614
Query: 539 YAVAADGVHCRDIDECVQEPRVCP-HACENVVGSYIC-KCPEGYRRTSAPQDSENACEDI 596
Y + G C DIDEC+ P CP C N GSY C C EG+R + C D+
Sbjct: 615 YRMTQRG-RCEDIDECL-NPSTCPDEQCVNSPGSYQCVPCTEGFRGWN------GQCLDV 666
Query: 597 NECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCE 653
+EC E ++C+ G C N +GS++C C G+ + D C D V+G+C+
Sbjct: 667 DECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK 722
Score = 152 bits (368), Expect = 6e-36
Identities = 154/574 (26%), Positives = 220/574 (38%), Gaps = 70/574 (12%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPP-CRGMAQC 126
I+EC +C+ G C +T + C C G++ D+ C+D++EC P C +C
Sbjct: 789 INECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNK-TCQDINECE--HPGLCGPQGEC 845
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICD-HGDCRNTIGSYRCECKPGYTLR 185
+N G+F C C G+ ++ CED+DEC + +CD HG C NT GS+RC C G+
Sbjct: 846 LNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAP 905
Query: 186 ENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHC-DDGFKAGP-NNDC---------VD 232
++ C DV+EC VC CEN+ G++LC C D+ + P C VD
Sbjct: 906 QDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVD 965
Query: 233 VNECREGGMVCRNGR-----CRNT----VGSFRCECAPGYTLTADGRNCRDVDECDELPH 283
V++ +E C C N V C C G G NC ++ C L
Sbjct: 966 VDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG---AGWGDNC-EIFPCPVLGT 1021
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPY-VCAGGECRNFNGGYVC 342
+ P E S AG G D DEC +C G C N GY C
Sbjct: 1022 AEFTEMCPKGKGFVPAGESSSEAG----GENYKDADECLLFGQEICKNGFCLNTRPGYEC 1077
Query: 343 ECPAGWRFDKTAAVCVDERKELCYDEWEA--GRCHRARPLQLARPECCCSEGAAWGRYCE 400
C G +D C D + C D G+C C C+ +
Sbjct: 1078 YCKQGTYYDPVKLQCFD--MDECQDPSSCIDGQCVNTE----GSYNCFCTHPMVLDASEK 1131
Query: 401 RCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLA 460
RC P + +I + + + + L + V VG + T+ C C G
Sbjct: 1132 RCIRPAESN-EQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTE----CCCLYGEAWG 1186
Query: 461 PDGLSCV--DADECALDPRI--------CGNGTCSNTRGGYECQCSPGFTQGPDQTCVD- 509
C D+D+ A I G + Y + P F Q +
Sbjct: 1187 MQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEE 1246
Query: 510 --VDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ---EPRVCPHA 564
+EC RC + C C GY + + C D++EC + +C +A
Sbjct: 1247 LQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNA 1306
Query: 565 -CENVVGSYICKCPEGYRRTSAPQDSENACEDIN 597
C N GSY C C GY P D N C +N
Sbjct: 1307 KCINTDGSYKCLCLPGY----VPSDKPNYCTPLN 1336
Score = 102 bits (245), Expect = 5e-21
Identities = 48/115 (41%), Positives = 64/115 (55%), Gaps = 9/115 (7%)
Query: 747 DVDECA----AIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNT 798
D+DEC + G C G FRC CG GY+ A + C D+DEC R C NT
Sbjct: 706 DIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNT 765
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE 852
+GS+ C+C GY G +C D++EC D CQ+ C NT GSY+C+C DG++
Sbjct: 766 EGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ 820
Score = 93.5 bits (222), Expect = 3e-18
Identities = 47/115 (40%), Positives = 62/115 (53%), Gaps = 11/115 (9%)
Query: 747 DVDECAAIPGLC-------APGRFRCV-CGPGYRPAGEVCADVDECAVRPPPC-DQLCHN 797
D+DEC P C +PG ++CV C G+R C DVDEC + P C + C N
Sbjct: 625 DIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDEC-LEPNVCANGDCSN 682
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+GSY C C GY D +CRD+DEC++ C NTEGS+ C+C GY+
Sbjct: 683 LEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQ 737
Score = 93.5 bits (222), Expect = 3e-18
Identities = 49/116 (42%), Positives = 62/116 (53%), Gaps = 15/116 (12%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQ--L 794
D++EC PGLC P G F CVC G+ + G C D+DEC V CD
Sbjct: 829 DINECEH-PGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGF 886
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCED 849
C NT GS+ CLC G++ +DG C DV+ECE + C + C N EGS+ C C D
Sbjct: 887 CDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCAD 942
Score = 91.1 bits (216), Expect = 2e-17
Identities = 44/116 (37%), Positives = 62/116 (53%), Gaps = 11/116 (9%)
Query: 747 DVDECAAIPGLCAPG-------RFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQ-LCH 796
+++EC P +C G R+ C+C GYR + + C D+DEC C Q C
Sbjct: 500 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 559
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGY 851
NT+GS+ C+C G+ E+G NC DVDEC R + C NT G++ C C+ GY
Sbjct: 560 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGY 615
Score = 90.6 bits (215), Expect = 2e-17
Identities = 47/119 (39%), Positives = 60/119 (50%), Gaps = 12/119 (10%)
Query: 747 DVDECAAIPGLCA-------PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHN 797
DVDEC P +CA G + C C GY P + C D+DEC + C N
Sbjct: 665 DVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKN 723
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRG 855
T+GS+ C C GY+L C D+DEC+ H C C NTEGS++C C+ GY G
Sbjct: 724 TEGSFRCTCGQGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASG 781
Score = 86.2 bits (204), Expect = 4e-16
Identities = 90/310 (29%), Positives = 124/310 (40%), Gaps = 31/310 (10%)
Query: 38 CPPRGSPAHTA---LCGEKPGEYINPVTNETKPIDECDIMPQLCKP-GTCHDTPTGFQCG 93
C P+G +T C + G I+ + IDEC + +C G C +T F+C
Sbjct: 839 CGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCL 897
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPP-GYRLTPSLDECE- 151
C G++ C DV+EC C G A C N+ G+F C C +P +C
Sbjct: 898 CYQGFQAPQDGQGCVDVNECELLSGVC-GEAFCENVEGSFLCVCADENQEYSPMTGQCRS 956
Query: 152 ----DVDECGDQRICDHGDCR-NTIGSYRCE--CKPGYTLRENVCRDV----DECSR-PR 199
D+D DQ + +C N + C+ P T +E C D C P
Sbjct: 957 RTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPC 1016
Query: 200 PVCRNGT-CENLPGA--YLCHCDDGFKAGPNNDCVDVNECREGGM-VCRNGRCRNTVGSF 255
PV E P ++ + +AG N D +EC G +C+NG C NT +
Sbjct: 1017 PVLGTAEFTEMCPKGKGFVPAGESSSEAGGEN-YKDADECLLFGQEICKNGFCLNTRPGY 1075
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--R 313
C C G C D+DEC + P C DG C NT G Y C C L +
Sbjct: 1076 ECYCKQGTYYDPVKLQCFDMDECQD-PSSC-IDG--QCVNTEGSYNCFCTHPMVLDASEK 1131
Query: 314 RCVDRDECKE 323
RC+ E E
Sbjct: 1132 RCIRPAESNE 1141
Score = 85.0 bits (201), Expect = 1e-15
Identities = 60/173 (34%), Positives = 77/173 (44%), Gaps = 14/173 (8%)
Query: 246 GRC-RNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
GRC + T+GS + PG + D C + PS N EC
Sbjct: 237 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPK--KPSYHGYNQMMECL- 293
Query: 305 GAGWKLVGRR-CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV----- 358
G+K V C D +EC +L VC GEC N G Y C C G+ D T + CV
Sbjct: 294 -PGYKRVNNTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV 351
Query: 359 -DERKELCYDEWEAGR-CHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAE 409
E K CY +GR C + L + CCCS G AWG +CE+CP P +A+
Sbjct: 352 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAK 404
Score = 83.4 bits (197), Expect = 3e-15
Identities = 58/167 (34%), Positives = 73/167 (43%), Gaps = 12/167 (7%)
Query: 3 WNEEDQSCAGAVGVPQ-TKYLCCCSVGHAWGAPCEA--CPPRGSPAHTALC----GEKP- 54
+N D S V P TK CCC+ G WG CE CP G+ T +C G P
Sbjct: 978 YNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPA 1037
Query: 55 GEYINPVTNET-KPIDECDIMPQ-LCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDE 112
GE + E K DEC + Q +CK G C +T G++C C G +D C D+DE
Sbjct: 1038 GESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDE 1097
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQ 159
C P QCVN G++ C C L S C E +Q
Sbjct: 1098 CQ--DPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQ 1142
Score = 83.0 bits (196), Expect = 4e-15
Identities = 42/127 (33%), Positives = 63/127 (49%), Gaps = 16/127 (12%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYR-PAGEVCADVDECAVRPPPCDQL--CH 796
D++EC +C G + C C G++ + C D++EC P C C
Sbjct: 788 DINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECL 846
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE-- 852
NT+GS+ C+C+ G+ + DG C D+DEC +T C C NT GS+ C C G++
Sbjct: 847 NTEGSFHCVCQQGFSISADGRTCEDIDECVNNT-VCDSHGFCDNTAGSFRCLCYQGFQAP 905
Query: 853 KRGDACV 859
+ G CV
Sbjct: 906 QDGQGCV 912
Score = 81.4 bits (192), Expect = 1e-14
Identities = 48/137 (35%), Positives = 62/137 (45%), Gaps = 31/137 (22%)
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTD 634
+C GY+R + C+DINEC+ Q +C G C+NT GS+ C C GF P +
Sbjct: 291 ECLPGYKRVN-----NTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSS 344
Query: 635 C------IDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCT 688
C I G CYR + SGR H+TK CCC+
Sbjct: 345 CVPDPPVISEEKGPCYRLVSSGR-------------------QCMHPLSVHLTKQLCCCS 385
Query: 689 LGAAWGSECELCPAPGS 705
+G AWG CE CP PG+
Sbjct: 386 VGKAWGPHCEKCPLPGT 402
Score = 81.0 bits (191), Expect = 2e-14
Identities = 50/121 (41%), Positives = 58/121 (47%), Gaps = 15/121 (12%)
Query: 747 DVDECAAIPGLCAPGR-------FRC-VCGPGYRPAGEV-CADVDECAVRPPPC-DQLCH 796
DVDEC P +C G FRC C GYR C D+DEC + P C D+ C
Sbjct: 584 DVDECLR-PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDEC-LNPSTCPDEQCV 641
Query: 797 NTDGSYDCL-CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
N+ GSY C+ C G+ C DVDEC CSN EGSY CSC GY +
Sbjct: 642 NSPGSYQCVPCTEGFR--GWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTP 699
Query: 856 D 856
D
Sbjct: 700 D 700
Score = 72.5 bits (170), Expect = 6e-12
Identities = 40/109 (36%), Positives = 57/109 (52%), Gaps = 7/109 (6%)
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWG-RYCERCPAPDSAEF---MRICQGGMGR 420
C+ E +C +A P + +CC + G +WG C++CP S M C G R
Sbjct: 239 CFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKR 298
Query: 421 PNLT--QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
N T QD++EC+++ VC G C+NT GS+RC C G+ P SCV
Sbjct: 299 VNNTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 346
Score = 67.7 bits (158), Expect = 2e-10
Identities = 48/166 (28%), Positives = 67/166 (40%), Gaps = 31/166 (18%)
Query: 6 EDQSCAGAVGVPQTKYL-CCCSVGHAWGAPCEACPPRGSPAHTALCG------EKP---- 54
++ C+ + QT Y CCC G AWG C CP + S + LC +P
Sbjct: 1159 DEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRD 1218
Query: 55 --GEYINPVTNETKP---------------IDECDIMPQLCKPGTCHDTPTGFQCGCDHG 97
++ T E P +EC I+ C+ G C G+ C C G
Sbjct: 1219 ALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGIL-NGCENGRCVRVQEGYTCDCFDG 1277
Query: 98 YEHDNTSHLCRDVDECSW--GRPPCRGMAQCVNLPGAFECRCPPGY 141
Y D C DV+EC R A+C+N G+++C C PGY
Sbjct: 1278 YHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1323
Score = 62.1 bits (144), Expect = 8e-09
Identities = 34/103 (33%), Positives = 49/103 (47%), Gaps = 4/103 (3%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC-RCPP 139
G C G QCG + C SWG C+ + + G + C P
Sbjct: 237 GRCFQETIGSQCG--KALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLP 294
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY 182
GY+ + C+D++EC Q +C +G+C NT+GSYRC CK G+
Sbjct: 295 GYKRVNNTF-CQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 336
Score = 60.5 bits (140), Expect = 2e-08
Identities = 44/129 (34%), Positives = 59/129 (45%), Gaps = 10/129 (7%)
Query: 165 GDC-RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAY----LCHCD 219
G C + TIGS + PG + +E+ C V S C+ C P + + C
Sbjct: 237 GRCFQETIGSQCGKALPGLSKQEDCCGTVGT-SWGFNKCQK--CPKKPSYHGYNQMMECL 293
Query: 220 DGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDEC 278
G+K N C D+NEC+ G VC NG C NT+GS+RC C G+ +C D
Sbjct: 294 PGYKRVNNTFCQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVI 352
Query: 279 DELPHPCGR 287
E PC R
Sbjct: 353 SEEKGPCYR 361
Score = 59.3 bits (137), Expect = 6e-08
Identities = 30/79 (37%), Positives = 38/79 (48%), Gaps = 7/79 (8%)
Query: 565 CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED---LCSGGVCINTDGSFLCD 621
C V Y C C +GY +A C D+NEC+E + LC CINTDGS+ C
Sbjct: 1263 CVRVQEGYTCDCFDGYHLDTAKM----TCVDVNECDELNNRMSLCKNAKCINTDGSYKCL 1318
Query: 622 CDAGFEPSEDGTDCIDRRT 640
C G+ PS+ C T
Sbjct: 1319 CLPGYVPSDKPNYCTPLNT 1337
Score = 58.8 bits (136), Expect = 8e-08
Identities = 34/93 (36%), Positives = 42/93 (45%), Gaps = 10/93 (10%)
Query: 765 CVCGPGYRPAGEVCA--------DVDECAVRPPP-CDQ-LCHNTDGSYDCLCRTGYELDE 814
C G G+ PAGE + D DEC + C C NT Y+C C+ G D
Sbjct: 1028 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDP 1087
Query: 815 DGANCRDVDECERDTHTCQQICSNTEGSYECSC 847
C D+DEC+ + C NTEGSY C C
Sbjct: 1088 VKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFC 1120
Score = 50.4 bits (115), Expect = 3e-05
Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 4/74 (5%)
Query: 782 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTH---TCQQI-CS 837
+EC + + C Y C C GY LD C DV+EC+ + C+ C
Sbjct: 1250 EECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCI 1309
Query: 838 NTEGSYECSCEDGY 851
NT+GSY+C C GY
Sbjct: 1310 NTDGSYKCLCLPGY 1323
Score = 48.8 bits (111), Expect = 8e-05
Identities = 30/73 (41%), Positives = 35/73 (47%), Gaps = 8/73 (10%)
Query: 452 ECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT---CV 508
EC GY + C D +EC L +C NG C NT G Y C C GF GPD T CV
Sbjct: 291 ECLPGYKRV-NNTFCQDINECQLQG-VCPNGECLNTMGSYRCTCKIGF--GPDPTFSSCV 346
Query: 509 -DVDECAEGRASC 520
D +E + C
Sbjct: 347 PDPPVISEEKGPC 359
Score = 48.8 bits (111), Expect = 8e-05
Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCI 636
PE +++ + +INEC D+C G CIN + C C G+ SE C+
Sbjct: 482 PEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCV 541
Query: 637 DRRTGTCYRSLVS-GRCE 653
D T + L S GRCE
Sbjct: 542 DIDECTQVQHLCSQGRCE 559
Score = 48.0 bits (109), Expect = 1e-04
Identities = 19/36 (52%), Positives = 22/36 (61%)
Query: 8 QSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGS 43
+ C + V TK LCCCSVG AWG CE CP G+
Sbjct: 367 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGT 402
Score = 44.0 bits (99), Expect = 0.002
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 5/101 (4%)
Query: 23 CCCSVGHAWGA-PCEACPPRGS-PAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKP 80
CC +VG +WG C+ CP + S + + PG Y + I+EC + +C
Sbjct: 261 CCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPG-YKRVNNTFCQDINECQLQG-VCPN 318
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPC 120
G C +T ++C C G+ D T C D S + PC
Sbjct: 319 GECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPC 359
Score = 43.6 bits (98), Expect = 0.003
Identities = 17/46 (36%), Positives = 25/46 (54%)
Query: 494 QCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGY 539
+C PG+ + + C D++EC C NT GS+RCTC G+
Sbjct: 291 ECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 336
Score = 42.7 bits (96), Expect = 0.005
Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 767 CGPGYRPAGEV-CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
C PGY+ C D++EC ++ + C NT GSY C C+ G+ D ++C
Sbjct: 292 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 345
Score = 38.3 bits (85), Expect = 0.11
Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 535 CPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGY 580
C GY + C+DI+EC Q VCP+ C N +GSY C C G+
Sbjct: 292 CLPGYK-RVNNTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGF 336
Score = 37.1 bits (82), Expect = 0.27
Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 3/57 (5%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDEC 150
C GY+ N + C+D++EC + C +C+N G++ C C G+ P+ C
Sbjct: 292 CLPGYKRVNNT-FCQDINECQL-QGVCPN-GECLNTMGSYRCTCKIGFGPDPTFSSC 345
Score = 37.1 bits (82), Expect = 0.27
Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C GY+ + C+D++EC+ C NT GSY C+C+ G+
Sbjct: 292 CLPGYKR-VNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 336
>X62009-1|CAB56757.1| 754|Homo sapiens fibrillin 5 protein.
Length = 754
Score = 377 bits (927), Expect = e-103
Identities = 200/528 (37%), Positives = 263/528 (49%), Gaps = 54/528 (10%)
Query: 152 DVDECG-DQRICDHGDCRNTIGSYRCECKPGYT--LRENVCRDVDECSRPRPVCRNGTCE 208
D++EC D IC +G C N GSYRC C GY C D+DEC R +C NG C
Sbjct: 16 DINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCR 75
Query: 209 NLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTA 267
N PG+Y C C G+ + C D+NEC C NG CRN +GSF CEC+PG L++
Sbjct: 76 NTPGSYSCTCPPGYVFRTETETCEDINECESNP--CVNGACRNNLGSFNCECSPGSKLSS 133
Query: 268 DGRNCRDVDECDELPHPCGRDGNPS-C-TNTNGGY---EC--SCGAGW------------ 308
G C D L C + S C N NG EC + GA W
Sbjct: 134 TGLIC-----IDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTA 188
Query: 309 ------KLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
++ G C D +EC+ P VC G C N G + CECP G D T VC+D R
Sbjct: 189 CPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRM 248
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPN 422
E CY +W+ C P + CCC+ GAAWG CE CP P + E+ +C G G N
Sbjct: 249 EQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFAN 308
Query: 423 ----LT-----QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
LT +D++EC+ P +C G+C NT GSF+C C G+ L + +C D DEC
Sbjct: 309 RGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECR 368
Query: 474 LDPRICGNGTCSNTRGGYECQCSPGFTQG--PDQTCVDVDECAEGRASCT-FRCHNTAGS 530
+ P +CG+G C NT G +EC+C G+ G + C+D+D C C C NT GS
Sbjct: 369 ISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGS 428
Query: 531 FRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDS 589
F+C CP G+ ++ C DI+EC +C + C N++G+Y C C GY+ T Q
Sbjct: 429 FQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQ-- 486
Query: 590 ENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+EC C C N++GS+ C C G+ DG C D
Sbjct: 487 --GCTDIDECMIMNGGCD-TQCTNSEGSYECSCSEGYALMPDGRSCAD 531
Score = 368 bits (906), Expect = e-101
Identities = 222/636 (34%), Positives = 294/636 (46%), Gaps = 89/636 (13%)
Query: 61 VTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+T + + I+EC + P +C G C + ++C C+ GYE D + C D+DEC R C
Sbjct: 10 ITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLC 69
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
C N PG++ C CPPGY + CED++EC + C +G CRN +GS+ CEC P
Sbjct: 70 DN-GLCRNTPGSYSCTCPPGYVFRTETETCEDINEC-ESNPCVNGACRNNLGSFNCECSP 127
Query: 181 GYTLRENVCRDVDECSRPRPV-CRNGTCE-NLPGAYL------------------CHCDD 220
G L +D + ++ CE N+ GA L C D
Sbjct: 128 GSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDT 187
Query: 221 GFKAG----PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV- 275
G C DVNEC VC NGRC N+ GSF CEC G TL GR C D+
Sbjct: 188 ACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIR 247
Query: 276 -DEC------DELPHPC-GRDGNPSCTNTNGG----------------YECSC--GAGWK 309
++C DE HP G+ +C G YE C GAG+
Sbjct: 248 MEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFA 307
Query: 310 -----LVGRRCV-DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
L GR D +ECK P +C G+CRN G + C C +G+ D C D
Sbjct: 308 NRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTD---- 363
Query: 364 LCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNL 423
DE C + L C G C P E + G
Sbjct: 364 --IDE-----CRISPDL--------CGSGI-----CVNTPGSFECECFEGYESGFMMMKN 403
Query: 424 TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT 483
D+D C P +C GG CVNT+GSF+C+CP G+ L+P CVD +EC+L +C NG
Sbjct: 404 CMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGK 463
Query: 484 CSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVA 542
C N G Y+C C+PG+ PD Q C D+DEC C +C N+ GS+ C+C GYA+
Sbjct: 464 CVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALM 523
Query: 543 ADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEE 601
DG C DIDEC P +C C N+ G Y C C +G+ A D + C D+NEC+
Sbjct: 524 PDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGF---MASMDMK-TCIDVNECDL 579
Query: 602 QEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
++C G C NT GSF+C C G+ + T C D
Sbjct: 580 NSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTD 615
Score = 345 bits (848), Expect = 4e-94
Identities = 212/648 (32%), Positives = 291/648 (44%), Gaps = 75/648 (11%)
Query: 4 NEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTN 63
N +D C + K CC ++G AWG+PCE C TA C I VT
Sbjct: 149 NIQDSRCEVNINGATLKSECCATLGAAWGSPCERCE-----LDTA-CPRGLAR-IKGVTC 201
Query: 64 ETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDV--DEC--SWGRPP 119
E ++EC++ P +C G C ++ F C C G D T +C D+ ++C W
Sbjct: 202 ED--VNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDE 259
Query: 120 CRGMAQCVNLPGAFE---CRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRC 176
C +PG F C C G +EC + +C G G
Sbjct: 260 C-----IHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLT 314
Query: 177 ECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG-PNNDCVDVNE 235
+P Y +D++EC +C G C N G++ C C+ GF +C D++E
Sbjct: 315 G-RPFY-------KDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDE 366
Query: 236 CREGGMVCRNGRCRNTVGSFRCECAPGYTLT-ADGRNCRDVDECDELPHPCGRDGNPSCT 294
CR +C +G C NT GSF CEC GY +NC D+D C+ P C R G +C
Sbjct: 367 CRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLC-RGG--TCV 423
Query: 295 NTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDK 352
NT G ++C C G +L R CVD +EC +C G+C N G Y C C G++
Sbjct: 424 NTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATP 483
Query: 353 TAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
C D + + + G C EC CSEG A PD R
Sbjct: 484 DRQGCTDIDECMIMN----GGCDTQCTNSEGSYECSCSEGYAL--------MPDG----R 527
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC 472
C D+DEC PD+C GG+C N G +RC C DG++ + D +C+D +EC
Sbjct: 528 SCA----------DIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNEC 577
Query: 473 ALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFR--CHNTAG 529
L+ IC G C NT+G + C C G++ T C DVDEC G +C C N G
Sbjct: 578 DLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPG 637
Query: 530 SFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSAPQ 587
SF+C+C G+ +G+ C D DEC C C N GSY C C EG+
Sbjct: 638 SFKCSCREGW--IGNGIKCIDRDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGF-- 693
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
C D++EC E +LC G C+N G++ C+C+ GF P+ D C
Sbjct: 694 ----TCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSC 737
Score = 329 bits (809), Expect = 2e-89
Identities = 188/519 (36%), Positives = 254/519 (48%), Gaps = 53/519 (10%)
Query: 1 MEWNEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
++W+E++ C V CCC+VG AWG CE CP G+ + LC G + N
Sbjct: 253 LKWDEDE--CIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAG-FANR 309
Query: 61 ---VTNET--KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSW 115
+T K I+EC P +C G C +T F+C C+ G+ D C D+DEC
Sbjct: 310 GDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRI 369
Query: 116 GRPPCRGMAQCVNLPGAFECRCPPGYRL-TPSLDECEDVDEC-GDQRICDHGDCRNTIGS 173
C G CVN PG+FEC C GY + C D+D C + +C G C NT GS
Sbjct: 370 SPDLC-GSGICVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGS 428
Query: 174 YRCECKPGYTL---RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND- 229
++C+C G+ L RE+ C D++ECS +CRNG C N+ G Y C C+ G++A P+
Sbjct: 429 FQCDCPLGHELSPSRED-CVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQG 487
Query: 230 CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDG 289
C D++EC C + +C N+ GS+ C C+ GY L DGR+C D+DEC+ P C DG
Sbjct: 488 CTDIDECMIMNGGC-DTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDIC--DG 544
Query: 290 NPSCTNTNGGYECSCGAGW--KLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
CTN G Y C C G+ + + C+D +EC +C GEC N G ++C C G
Sbjct: 545 G-QCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLG 603
Query: 348 WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS 407
+ K C D DE E G H C A+ C P
Sbjct: 604 YSVKKGTTGCTD------VDECEIG-AHN------------CDMHAS----CLNIP---- 636
Query: 408 AEFMRIC-QGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLS 465
F C +G +G D DEC C + +CVNT GS+RC C +G+ DG +
Sbjct: 637 GSFKCSCREGWIGNGIKCIDRDECSNGTHQCSINAQCVNTPGSYRCACSEGF--TGDGFT 694
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD 504
C D DECA + +C NG C N G Y C+C GFT D
Sbjct: 695 CSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASD 733
Score = 308 bits (755), Expect = 8e-83
Identities = 165/453 (36%), Positives = 227/453 (50%), Gaps = 45/453 (9%)
Query: 108 RDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG-DQRICDHGD 166
+D++EC C +C N G+F+CRC G+ L C D+DEC +C G
Sbjct: 320 KDINECKAFPGMCT-YGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGI 378
Query: 167 CRNTIGSYRCECKPGYT---LRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK 223
C NT GS+ CEC GY + C D+D C R +CR GTC N G++ C C G +
Sbjct: 379 CVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHE 438
Query: 224 AGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELP 282
P+ DCVD+NEC +CRNG+C N +G+++C C PGY T D + C D+DEC +
Sbjct: 439 LSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMN 498
Query: 283 HPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGY 340
C + CTN+ G YECSC G+ L+ GR C D DEC+ P +C GG+C N G Y
Sbjct: 499 GGC----DTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEY 554
Query: 341 VCECPAGWRFDKTAAVCVDERK-ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYC 399
C C G+ C+D + +L + G C + + C C G +
Sbjct: 555 RCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFI----CHCQLGYS----- 605
Query: 400 ERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYV 458
+ +G G D+DEC + C + C+N GSF+C C +G++
Sbjct: 606 -------------VKKGTTG----CTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWI 648
Query: 459 LAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGR 517
+G+ C+D DEC+ C N C NT G Y C CS GFT G TC DVDECAE
Sbjct: 649 --GNGIKCIDRDECSNGTHQCSINAQCVNTPGSYRCACSEGFT-GDGFTCSDVDECAENI 705
Query: 518 ASC-TFRCHNTAGSFRCTCPYGYAVAADGVHCR 549
C +C N G++RC C G+ A+D C+
Sbjct: 706 NLCENGQCLNVPGAYRCECEMGFTPASDSRSCQ 738
Score = 306 bits (752), Expect = 2e-82
Identities = 213/656 (32%), Positives = 280/656 (42%), Gaps = 109/656 (16%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C PG T + I+EC+ P C G C + F C C G + +T +C D
Sbjct: 83 CTCPPGYVFRTETETCEDINECESNP--CVNGACRNNLGSFNCECSPGSKLSSTGLICID 140
Query: 110 V-----------DECSWGRPPCRGMAQCVNLPGA----------FECRCPPGYRLTPSLD 148
C ++C GA + CP G +
Sbjct: 141 SLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVT 200
Query: 149 ECEDVDECGD-QRICDHGDCRNTIGSYRCECKPGYTL--RENVCRDV-----------DE 194
CEDV+EC +C +G C N+ GS+ CEC G TL VC D+ DE
Sbjct: 201 -CEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDE 259
Query: 195 CSRPRP--------VCRNGT-----CENLPGA----YLCHCDDGFKAGPNNDCV------ 231
C P P C G CE P Y C G D +
Sbjct: 260 CIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFY 319
Query: 232 -DVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGN 290
D+NEC+ +C G+CRNT+GSF+C C G+ L + RNC D+DEC P CG +
Sbjct: 320 KDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCG---S 376
Query: 291 PSCTNTNGGYECSCGAGWK---LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
C NT G +EC C G++ ++ + C+D D C+ P +C GG C N G + C+CP G
Sbjct: 377 GICVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLG 436
Query: 348 WRFDKTAAVCVDERK-ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPD 406
+ CVD + L + G+C + +C C+ G PD
Sbjct: 437 HELSPSREDCVDINECSLSDNLCRNGKCVN----MIGTYQCSCNPGYQ--------ATPD 484
Query: 407 SAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
QG D+DEC + C +C N++GS+ C C +GY L PDG SC
Sbjct: 485 R-------QG-------CTDIDECMIMNGGC-DTQCTNSEGSYECSCSEGYALMPDGRSC 529
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTF-RC 524
D DEC +P IC G C+N G Y C C GF D +TC+DV+EC C F C
Sbjct: 530 ADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGEC 589
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP-HA-CENVVGSYICKCPEGYRR 582
NT GSF C C GY+V C D+DEC C HA C N+ GS+ C C EG+
Sbjct: 590 ENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIG 649
Query: 583 TSAPQDSENACEDINECEEQEDLCS-GGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C D +EC CS C+NT GS+ C C GF + DG C D
Sbjct: 650 NGI------KCIDRDECSNGTHQCSINAQCVNTPGSYRCACSEGF--TGDGFTCSD 697
Score = 255 bits (625), Expect = 4e-67
Identities = 151/471 (32%), Positives = 208/471 (44%), Gaps = 66/471 (14%)
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC 472
+C G+G +D++EC + PD+C G C N GS+RC C GY G +C+D DEC
Sbjct: 3 LCSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDEC 62
Query: 473 ALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTFRCHNTAGSF 531
++ +C NG C NT G Y C C PG+ + +TC D++EC E C N GSF
Sbjct: 63 LVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINEC-ESNPCVNGACRNNLGSF 121
Query: 532 RCTCPYGYAVAADGVHCRDI--DEC---VQEPR---------VCPHACENVVGSYICKCP 577
C C G +++ G+ C D C +Q+ R + C + ++ C
Sbjct: 122 NCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCE 181
Query: 578 EGYRRTSAPQDSEN----ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGT 633
T+ P+ CED+NECE +C G C+N+ GSF C+C G G
Sbjct: 182 RCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGR 241
Query: 634 DCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAW 693
C+D R CY C G CCC +GAAW
Sbjct: 242 VCLDIRMEQCYLKWDEDEC--------------------IHPVPGKFRMDACCCAVGAAW 281
Query: 694 GSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAA 753
G+ECE CP PG+ LC + D++EC A
Sbjct: 282 GTECEECPKPGTKEYETLCP--------------RGAGFANRGDVLTGRPFYKDINECKA 327
Query: 754 IPGLCAPGR-------FRCVCGPGYRPAGEV--CADVDECAVRPPPCDQ-LCHNTDGSYD 803
PG+C G+ F+C C G+ E C D+DEC + P C +C NT GS++
Sbjct: 328 FPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFE 387
Query: 804 CLCRTGYELD-EDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYE 852
C C GYE NC D+D CER+ C+ C NTEGS++C C G+E
Sbjct: 388 CECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHE 438
Score = 229 bits (560), Expect = 3e-59
Identities = 190/676 (28%), Positives = 271/676 (40%), Gaps = 99/676 (14%)
Query: 259 CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK--LVGRRCV 316
C+ G +T DGR D++EC P C N C N G Y C+C +G++ GR C+
Sbjct: 4 CSSGVGITVDGR---DINECALDPDICA---NGICENLRGSYRCNCNSGYEPDASGRNCI 57
Query: 317 DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC-H 375
D DEC +C G CRN G Y C CP G+ F C D +E E+ C +
Sbjct: 58 DIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCED------INECESNPCVN 111
Query: 376 RARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPD 435
A L C CS G+ C DS + C + +++ ++ +
Sbjct: 112 GACRNNLGSFNCECSPGSKLSSTGLICI--DSLK--GTCWLNIQDSRCEVNINGATLKSE 167
Query: 436 VCVGGRCVNTDGSFRCE----CPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGY 491
C RCE CP G G++C D +EC + P +C NG C N++G +
Sbjct: 168 CCATLGAAWGSPCERCELDTACPRGLARIK-GVTCEDVNECEVFPGVCPNGRCVNSKGSF 226
Query: 492 ECQCSPGFT-QGPDQTCV-----------DVDECAE---GR----ASCTF-------RCH 525
C+C G T G + C+ D DEC G+ A C C
Sbjct: 227 HCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECE 286
Query: 526 NT----AGSFRCTCPYGYAVAADG------VHCRDIDECVQEPRVCPHA-CENVVGSYIC 574
+ CP G A G +DI+EC P +C + C N +GS+ C
Sbjct: 287 ECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKC 346
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDC----DAGFEPSE 630
+C G+ A E C DI+EC DLC G+C+NT GSF C+C ++GF +
Sbjct: 347 RCNSGF----ALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMK 402
Query: 631 DGTDC--IDR-----RTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKA 683
+ D +R R GTC + S +C+
Sbjct: 403 NCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNG 462
Query: 684 QCCCTLGAAWGSECELCPA-PGSPAR-----LDLCTAVNLTPXXXXXXXXXXXXXXXXXX 737
+C +G +C P +P R +D C +N
Sbjct: 463 KCVNMIGTY---QCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEG 519
Query: 738 XXXXLD--VFADVDECAAIPGLC-------APGRFRCVCGPGYRPAGEV--CADVDECAV 786
D AD+DEC P +C PG +RC+C G+ + ++ C DV+EC +
Sbjct: 520 YALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDL 579
Query: 787 RPPPCD-QLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSY 843
C C NT GS+ C C+ GY + + C DVDECE H C C N GS+
Sbjct: 580 NSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSF 639
Query: 844 ECSCEDGYEKRGDACV 859
+CSC +G+ G C+
Sbjct: 640 KCSCREGWIGNGIKCI 655
Score = 171 bits (416), Expect = 9e-42
Identities = 84/227 (37%), Positives = 110/227 (48%), Gaps = 5/227 (2%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C G + P IDEC+ P +C G C + P ++C C G+ C D
Sbjct: 514 CSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCID 573
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG-DQRICD-HGDC 167
V+EC C +C N G+F C C GY + C DVDEC CD H C
Sbjct: 574 VNECDLNSNICM-FGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASC 632
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGP 226
N GS++C C+ G+ C D DECS C N C N PG+Y C C +GF G
Sbjct: 633 LNIPGSFKCSCREGWIGNGIKCIDRDECSNGTHQCSINAQCVNTPGSYRCACSEGF-TGD 691
Query: 227 NNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR 273
C DV+EC E +C NG+C N G++RCEC G+T +D R+C+
Sbjct: 692 GFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQ 738
Score = 82.6 bits (195), Expect = 5e-15
Identities = 46/122 (37%), Positives = 57/122 (46%), Gaps = 13/122 (10%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAGEVCADVDECAVRPPPC--DQLCH 796
DVDEC C PG F+C C G+ G C D DEC+ C + C
Sbjct: 615 DVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDRDECSNGTHQCSINAQCV 674
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRG 855
NT GSY C C G+ DG C DVDEC + + C+ C N G+Y C CE G+
Sbjct: 675 NTPGSYRCACSEGFT--GDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPAS 732
Query: 856 DA 857
D+
Sbjct: 733 DS 734
Score = 81.8 bits (193), Expect = 9e-15
Identities = 47/125 (37%), Positives = 57/125 (45%), Gaps = 15/125 (12%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQ--LC 795
DV+EC +C G F C C GY + C DVDEC + CD C
Sbjct: 573 DVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASC 632
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEK 853
N GS+ C CR G+ +G C D DEC TH C C NT GSY C+C +G+
Sbjct: 633 LNIPGSFKCSCREGWI--GNGIKCIDRDECSNGTHQCSINAQCVNTPGSYRCACSEGFTG 690
Query: 854 RGDAC 858
G C
Sbjct: 691 DGFTC 695
Score = 57.2 bits (132), Expect = 2e-07
Identities = 24/62 (38%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 760 PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGAN 818
PG +RC C G+ G C+DVDECA C+ C N G+Y C C G+ D +
Sbjct: 677 PGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRS 736
Query: 819 CR 820
C+
Sbjct: 737 CQ 738
Score = 32.7 bits (71), Expect = 5.7
Identities = 16/38 (42%), Positives = 20/38 (52%), Gaps = 7/38 (18%)
Query: 746 ADVDECAAIPGLC-------APGRFRCVCGPGYRPAGE 776
+DVDECA LC PG +RC C G+ PA +
Sbjct: 696 SDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASD 733
>AC019127-1|AAY24260.1| 697|Homo sapiens unknown protein.
Length = 697
Score = 375 bits (922), Expect = e-103
Identities = 247/725 (34%), Positives = 328/725 (45%), Gaps = 92/725 (12%)
Query: 153 VDECG-DQRICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCEN 209
++EC + IC G C N Y C C GY E C D+DEC++ + +C G CEN
Sbjct: 1 INECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCEN 60
Query: 210 LPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCE-CAPGYTLTA 267
G++LC C GF A +C+DV+EC VC G C NTVG+FRCE C GY +T
Sbjct: 61 TEGSFLCICPAGFMASEEGTNCIDVDECLRPD-VCGEGHCVNTVGAFRCEYCDSGYRMTQ 119
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC-SCGAGWKLVGRRCVDRDECKELPY 326
GR C D+DEC P C + C N+ G Y+C C G++ +C+D DEC E P
Sbjct: 120 RGR-CEDIDECLN-PSTCPDE---QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE-PN 173
Query: 327 VCAGGECRNFNGGYVCECPAGWRFDKTAAVC--VDERKE--LCYDEWEAGRCHRARPLQL 382
VCA G+C N G Y+C C G+ C +DE ++ LC + G+C
Sbjct: 174 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVN----GQCKNTE---- 225
Query: 383 ARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRC 442
C C +G ++C +D+DEC+ R +C G+C
Sbjct: 226 GSFRCTCGQGYQLSAAKDQC----------------------EDIDECQHR-HLCAHGQC 262
Query: 443 VNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG 502
NT+GSF+C C GY + G C D +EC D +C G C NT G Y+C C GF
Sbjct: 263 RNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD 322
Query: 503 PDQTCVDVDECAE-GRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC 561
++TC D++EC G C NT GSF C C G++++ADG C DIDECV
Sbjct: 323 DNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCD 382
Query: 562 PHA-CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC 620
H C+N GS+ C C +G++ APQD + C D+NECE +C C N +GSFLC
Sbjct: 383 SHGFCDNTAGSFRCLCYQGFQ---APQDGQ-GCVDVNECELLSGVCGEAFCENVEGSFLC 438
Query: 621 DC-DAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGH 679
C D E S C RT T L +P+ +
Sbjct: 439 VCADENQEYSPMTGQC-RSRTST---DLDVDVDQPK-EEKKECYYNLNDASLCDNVLAPN 493
Query: 680 VTKAQCCCTLGAAWGSECEL--CPAPGSPARLDLC-TAVNLTPXXXXXXXXXXXXXXXXX 736
VTK +CCCT G WG CE+ CP G+ ++C P
Sbjct: 494 VTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGG------- 546
Query: 737 XXXXXLDVFADVDECAAI------PGLCAPGR--FRCVCGPG--YRPAGEVCADVDECAV 786
+ + D DEC G C R + C C G Y P C D+DEC
Sbjct: 547 ------ENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ- 599
Query: 787 RPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECER--DTHTCQQIC-SNTEG 841
P C D C NT+GSY+C C LD C R + E+ +T Q +C +
Sbjct: 600 DPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSD 659
Query: 842 SYECS 846
Y CS
Sbjct: 660 EYVCS 664
Score = 319 bits (784), Expect = 2e-86
Identities = 175/476 (36%), Positives = 236/476 (49%), Gaps = 44/476 (9%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
I+EC + P +C G C + P + C C GY C D+DEC+ + C +C
Sbjct: 1 INECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC-SQGRCE 59
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCE-CKPGYTL-R 185
N G+F C CP G+ + C DVDEC +C G C NT+G++RCE C GY + +
Sbjct: 60 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 119
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLC-HCDDGFKAGPNNDCVDVNECREGGMVCR 244
C D+DEC P C + C N PG+Y C C +GF+ G N C+DV+EC E VC
Sbjct: 120 RGRCEDIDECLNP-STCPDEQCVNSPGSYQCVPCTEGFR-GWNGQCLDVDECLEPN-VCA 176
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
NG C N GS+ C C GYT T D ++CRD+DEC + + C N C NT G + C+C
Sbjct: 177 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQ-GNLC---VNGQCKNTEGSFRCTC 232
Query: 305 GAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
G G++L + C D DEC+ ++CA G+CRN G + C C G+R C D +
Sbjct: 233 GQGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE 291
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPN 422
C ++ C R + A G Y CP + + C
Sbjct: 292 --CLEDKSV--CQRGDCINTA------------GSYDCTCPDGFQLDDNKTC-------- 327
Query: 423 LTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGN 481
QD++EC P +C G C+NT+GSF C C G+ ++ DG +C D DEC + +
Sbjct: 328 --QDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSH 384
Query: 482 GTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASC-TFRCHNTAGSFRCTC 535
G C NT G + C C GF D Q CVDV+EC C C N GSF C C
Sbjct: 385 GFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 440
Score = 312 bits (766), Expect = 4e-84
Identities = 185/537 (34%), Positives = 249/537 (46%), Gaps = 63/537 (11%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+DEC + P +C G C + + C C GY CRD+DEC G G QC
Sbjct: 166 VDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNG--QCK 222
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE- 186
N G+F C C GY+L+ + D+CED+DEC + +C HG CRNT GS++C C GY
Sbjct: 223 NTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGL 282
Query: 187 -NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN 245
+ C D++EC + VC+ G C N G+Y C C DGF+ N C D+NEC G+
Sbjct: 283 GDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQ 342
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
G C NT GSF C C G++++ADGR C D+DEC C D + C NT G + C C
Sbjct: 343 GECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNT-VC--DSHGFCDNTAGSFRCLCY 399
Query: 306 AGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
G++ G+ CVD +EC+ L VC C N G ++C VC DE +E
Sbjct: 400 QGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLC-------------VCADENQE 446
Query: 364 LCYDEWEAGRCHRARPLQL---------ARPECCCSEGAAWGRYCERCPAPDSAEFMRIC 414
Y G+C L + EC + A C+ AP+ + C
Sbjct: 447 --YSPM-TGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDA--SLCDNVLAPNVTKQECCC 501
Query: 415 QGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV------- 467
G+G D C + P +G F CP G P G S
Sbjct: 502 TSGVGWG------DNCEIFPCPVLG------TAEFTEMCPKGKGFVPAGESSSEAGGENY 549
Query: 468 -DADECAL-DPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFRC 524
DADEC L IC NG C NTR GYEC C G P + C D+DEC + + +C
Sbjct: 550 KDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQC 609
Query: 525 HNTAGSFRCTCPYGYAVAADGVHC---RDIDECVQEPRVCPHAC-ENVVGSYICKCP 577
NT GS+ C C + + A C + +E ++E V C E++ Y+C P
Sbjct: 610 VNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRP 666
Score = 308 bits (755), Expect = 8e-83
Identities = 233/715 (32%), Positives = 305/715 (42%), Gaps = 95/715 (13%)
Query: 46 HTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSH 105
+T +C E G + + IDEC + LC G C +T F C C G+
Sbjct: 23 YTCICYE--GYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGT 80
Query: 106 LCRDVDECSWGRPPCRGMAQCVNLPGAFECR-CPPGYRLTPSLDECEDVDECGDQRICDH 164
C DVDEC RP G CVN GAF C C GYR+T CED+DEC + C
Sbjct: 81 NCIDVDECL--RPDVCGEGHCVNTVGAFRCEYCDSGYRMTQR-GRCEDIDECLNPSTCPD 137
Query: 165 GDCRNTIGSYRC-ECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK 223
C N+ GSY+C C G+ C DVDEC P VC NG C NL G+Y+C C G+
Sbjct: 138 EQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN-VCANGDCSNLEGSYMCSCHKGYT 196
Query: 224 AGPNND-CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELP 282
P++ C D++EC++G + C NG+C+NT GSFRC C GY L+A C D+DEC
Sbjct: 197 RTPDHKHCRDIDECQQGNL-CVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHR- 254
Query: 283 HPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGECRNFNGGY 340
H C C NT G ++C C G++ +G C D +EC E VC G+C N G Y
Sbjct: 255 HLCAHG---QCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSY 311
Query: 341 VCECPAGWRFDKTAAVCVD----ERKELCYDEWEAGRCHRARPLQLARPECCCSEG---A 393
C CP G++ D C D E LC + G C C C +G +
Sbjct: 312 DCTCPDGFQLDDNKT-CQDINECEHPGLCGPQ---GECLNTE----GSFHCVCQQGFSIS 363
Query: 394 AWGRYCE---RC---PAPDS--------AEFMRICQGGMGRPNLTQ---DLDECRVRPDV 436
A GR CE C DS F +C G P Q D++EC + V
Sbjct: 364 ADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGV 423
Query: 437 CVGGRCVNTDGSFRCECPD-GYVLAPDGLSC---------VDAD-------ECAL---DP 476
C C N +GSF C C D +P C VD D EC D
Sbjct: 424 CGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDA 483
Query: 477 RICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAE-GRASCTFRCHNTAGSFRCTC 535
+C N N EC C+ G G + C ++ C G A T C G
Sbjct: 484 SLCDNVLAPNVTK-QECCCTSGVGWGDN--C-EIFPCPVLGTAEFTEMCPKGKGFV---- 535
Query: 536 PYGYAVA-ADGVHCRDIDECVQ-EPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSENA 592
P G + + A G + +D DEC+ +C + C N Y C C +G + +
Sbjct: 536 PAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQG----TYYDPVKLQ 591
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRC 652
C D++EC++ C G C+NT+GS+ C C P D ++R C R S
Sbjct: 592 CFDMDECQDPSS-CIDGQCVNTEGSYNCFCT---HPMV--LDASEKR---CIRPAESNEQ 642
Query: 653 --EPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGS 705
E + T +CCC G AWG +C LCP S
Sbjct: 643 IEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDS 697
Score = 102 bits (245), Expect = 5e-21
Identities = 48/115 (41%), Positives = 64/115 (55%), Gaps = 9/115 (7%)
Query: 747 DVDECA----AIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNT 798
D+DEC + G C G FRC CG GY+ A + C D+DEC R C NT
Sbjct: 206 DIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNT 265
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE 852
+GS+ C+C GY G +C D++EC D CQ+ C NT GSY+C+C DG++
Sbjct: 266 EGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ 320
Score = 93.5 bits (222), Expect = 3e-18
Identities = 47/115 (40%), Positives = 62/115 (53%), Gaps = 11/115 (9%)
Query: 747 DVDECAAIPGLC-------APGRFRCV-CGPGYRPAGEVCADVDECAVRPPPC-DQLCHN 797
D+DEC P C +PG ++CV C G+R C DVDEC + P C + C N
Sbjct: 125 DIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDEC-LEPNVCANGDCSN 182
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+GSY C C GY D +CRD+DEC++ C NTEGS+ C+C GY+
Sbjct: 183 LEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQ 237
Score = 93.5 bits (222), Expect = 3e-18
Identities = 49/116 (42%), Positives = 62/116 (53%), Gaps = 15/116 (12%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQ--L 794
D++EC PGLC P G F CVC G+ + G C D+DEC V CD
Sbjct: 329 DINECEH-PGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGF 386
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCED 849
C NT GS+ CLC G++ +DG C DV+ECE + C + C N EGS+ C C D
Sbjct: 387 CDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCAD 442
Score = 90.6 bits (215), Expect = 2e-17
Identities = 47/119 (39%), Positives = 60/119 (50%), Gaps = 12/119 (10%)
Query: 747 DVDECAAIPGLCA-------PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHN 797
DVDEC P +CA G + C C GY P + C D+DEC + C N
Sbjct: 165 DVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKN 223
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRG 855
T+GS+ C C GY+L C D+DEC+ H C C NTEGS++C C+ GY G
Sbjct: 224 TEGSFRCTCGQGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASG 281
Score = 90.2 bits (214), Expect = 3e-17
Identities = 44/115 (38%), Positives = 61/115 (53%), Gaps = 11/115 (9%)
Query: 748 VDECAAIPGLCAPG-------RFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQ-LCHN 797
++EC P +C G R+ C+C GYR + + C D+DEC C Q C N
Sbjct: 1 INECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCEN 60
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGY 851
T+GS+ C+C G+ E+G NC DVDEC R + C NT G++ C C+ GY
Sbjct: 61 TEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGY 115
Score = 86.2 bits (204), Expect = 4e-16
Identities = 90/310 (29%), Positives = 124/310 (40%), Gaps = 31/310 (10%)
Query: 38 CPPRGSPAHTA---LCGEKPGEYINPVTNETKPIDECDIMPQLCKP-GTCHDTPTGFQCG 93
C P+G +T C + G I+ + IDEC + +C G C +T F+C
Sbjct: 339 CGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCL 397
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPP-GYRLTPSLDECE- 151
C G++ C DV+EC C G A C N+ G+F C C +P +C
Sbjct: 398 CYQGFQAPQDGQGCVDVNECELLSGVC-GEAFCENVEGSFLCVCADENQEYSPMTGQCRS 456
Query: 152 ----DVDECGDQRICDHGDCR-NTIGSYRCE--CKPGYTLRENVCRDV----DECSR-PR 199
D+D DQ + +C N + C+ P T +E C D C P
Sbjct: 457 RTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPC 516
Query: 200 PVCRNGT-CENLPGA--YLCHCDDGFKAGPNNDCVDVNECREGGM-VCRNGRCRNTVGSF 255
PV E P ++ + +AG N D +EC G +C+NG C NT +
Sbjct: 517 PVLGTAEFTEMCPKGKGFVPAGESSSEAGGEN-YKDADECLLFGQEICKNGFCLNTRPGY 575
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--R 313
C C G C D+DEC + P C DG C NT G Y C C L +
Sbjct: 576 ECYCKQGTYYDPVKLQCFDMDECQD-PSSC-IDG--QCVNTEGSYNCFCTHPMVLDASEK 631
Query: 314 RCVDRDECKE 323
RC+ E E
Sbjct: 632 RCIRPAESNE 641
Score = 83.0 bits (196), Expect = 4e-15
Identities = 45/125 (36%), Positives = 66/125 (52%), Gaps = 14/125 (11%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYRPA--GEVCADVDECAVRPPPCDQ-LCH 796
D+DEC + LC+ GR F C+C G+ + G C DVDEC +RP C + C
Sbjct: 42 DIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGEGHCV 100
Query: 797 NTDGSYDC-LCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC-SCEDGYEKR 854
NT G++ C C +GY + + G C D+DEC + + C N+ GSY+C C +G+
Sbjct: 101 NTVGAFRCEYCDSGYRMTQRG-RCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGW 159
Query: 855 GDACV 859
C+
Sbjct: 160 NGQCL 164
Score = 83.0 bits (196), Expect = 4e-15
Identities = 42/127 (33%), Positives = 63/127 (49%), Gaps = 16/127 (12%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYR-PAGEVCADVDECAVRPPPCDQL--CH 796
D++EC +C G + C C G++ + C D++EC P C C
Sbjct: 288 DINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECL 346
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE-- 852
NT+GS+ C+C+ G+ + DG C D+DEC +T C C NT GS+ C C G++
Sbjct: 347 NTEGSFHCVCQQGFSISADGRTCEDIDECVNNT-VCDSHGFCDNTAGSFRCLCYQGFQAP 405
Query: 853 KRGDACV 859
+ G CV
Sbjct: 406 QDGQGCV 412
Score = 83.0 bits (196), Expect = 4e-15
Identities = 58/167 (34%), Positives = 73/167 (43%), Gaps = 12/167 (7%)
Query: 3 WNEEDQSCAGAVGVPQ-TKYLCCCSVGHAWGAPCEA--CPPRGSPAHTALC----GEKP- 54
+N D S V P TK CCC+ G WG CE CP G+ T +C G P
Sbjct: 478 YNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPA 537
Query: 55 GEYINPVTNET-KPIDECDIMPQ-LCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDE 112
GE + E K DEC + Q +CK G C +T G++C C G +D C D+DE
Sbjct: 538 GESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDE 597
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQ 159
C P QCVN G++ C C L S C E +Q
Sbjct: 598 CQ--DPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQ 642
Score = 81.0 bits (191), Expect = 2e-14
Identities = 50/121 (41%), Positives = 58/121 (47%), Gaps = 15/121 (12%)
Query: 747 DVDECAAIPGLCAPGR-------FRC-VCGPGYRPAGEV-CADVDECAVRPPPC-DQLCH 796
DVDEC P +C G FRC C GYR C D+DEC + P C D+ C
Sbjct: 84 DVDECLR-PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDEC-LNPSTCPDEQCV 141
Query: 797 NTDGSYDCL-CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
N+ GSY C+ C G+ C DVDEC CSN EGSY CSC GY +
Sbjct: 142 NSPGSYQCVPCTEGFR--GWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTP 199
Query: 856 D 856
D
Sbjct: 200 D 200
Score = 58.8 bits (136), Expect = 8e-08
Identities = 34/93 (36%), Positives = 42/93 (45%), Gaps = 10/93 (10%)
Query: 765 CVCGPGYRPAGEVCA--------DVDECAVRPPP-CDQ-LCHNTDGSYDCLCRTGYELDE 814
C G G+ PAGE + D DEC + C C NT Y+C C+ G D
Sbjct: 528 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDP 587
Query: 815 DGANCRDVDECERDTHTCQQICSNTEGSYECSC 847
C D+DEC+ + C NTEGSY C C
Sbjct: 588 VKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFC 620
Score = 36.3 bits (80), Expect = 0.46
Identities = 15/39 (38%), Positives = 20/39 (51%), Gaps = 1/39 (2%)
Query: 6 EDQSCAGAVGVPQTKYL-CCCSVGHAWGAPCEACPPRGS 43
++ C+ + QT Y CCC G AWG C CP + S
Sbjct: 659 DEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDS 697
>X62008-1|CAB56534.1| 517|Homo sapiens fibrillin 15 protein.
Length = 517
Score = 299 bits (733), Expect = 3e-80
Identities = 145/354 (40%), Positives = 188/354 (53%), Gaps = 16/354 (4%)
Query: 6 EDQSCAGAVGVPQTKYLCCCSVGHAWGAP-CEACPPRGSPAHTALCGEKPGEYINPVTNE 64
ED+ C + CCCSVG AWG CE CP R +P + LC PG +TN
Sbjct: 167 EDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNG 226
Query: 65 T---KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
K I+EC ++P LC G C +T F+C CD G+ D+ C D+DEC C
Sbjct: 227 KPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLC- 285
Query: 122 GMAQCVNLPGAFECRCPPGYRL-TPSLDECEDVDEC-GDQRICDHGDCRNTIGSYRCECK 179
G QCVN PG FEC+C GY + C D+DEC D +C G C NT GSYRCEC
Sbjct: 286 GRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECP 345
Query: 180 PGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNEC 236
PG+ L N+ C D++EC +C NG C NL G Y C C+ G+ + P+ CVD++EC
Sbjct: 346 PGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDEC 405
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
C C N+ GS+ C C PG+ L D R+C D+DEC++ P+ C DG CTN
Sbjct: 406 SIMNGGCET-FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNIC--DGG-QCTNI 461
Query: 297 NGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
G Y C C G+ + CVD +EC P +C G C N G ++C C G+
Sbjct: 462 PGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGY 515
Score = 256 bits (628), Expect = 2e-67
Identities = 166/530 (31%), Positives = 237/530 (44%), Gaps = 68/530 (12%)
Query: 126 CVNLPGAFECRCPPGYRLTPSLDEC-EDVDECGDQRICD------------HGDCRNTIG 172
C N PG+F C C L P+ C E + Q + D C +++G
Sbjct: 25 CKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLG 84
Query: 173 SY------RCE----CKPGYT-LRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDG 221
+ C+ C GY+ ++ C D+DEC VC+NG C N G++ C C G
Sbjct: 85 AAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSG 144
Query: 222 FKAGPNND-CVDVNECREGGMVCRNGRCRNTV-GSFRCECAPGYTLTADGRNCRDVDECD 279
C+D+ + + C + G R + A G +EC+
Sbjct: 145 MTLDATGRICLDIR-LETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWG-----TEECE 198
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGG 339
E P + C G G D +ECK +P +C G+CRN G
Sbjct: 199 ECPMRNTPEYEELCPRGPGFATKEITNGKPFFK----DINECKMIPSLCTHGKCRNTIGS 254
Query: 340 YVCECPAGWRFDKTAAVCVD-ERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRY 398
+ C C +G+ D C D + + D G+C P EC C EG G
Sbjct: 255 FKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT-PGDF---ECKCDEGYESGFM 310
Query: 399 CERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYV 458
M+ C D+DEC+ P +C GG C NT+GS+RCECP G+
Sbjct: 311 -----------MMKNCM----------DIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQ 349
Query: 459 LAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGR 517
L+P+ +C+D +EC L +C NG C N G Y+C C+PG+ PD+ CVD+DEC+
Sbjct: 350 LSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMN 409
Query: 518 ASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKC 576
C C N+ GS+ C+C G+A+ D C DIDEC P +C C N+ G Y C C
Sbjct: 410 GGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLC 469
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
+G+ A +D + C D+NEC+ ++C G C NT GSF+C CD G+
Sbjct: 470 YDGF---MASEDMK-TCVDVNECDLNPNICLSGTCENTKGSFICHCDMGY 515
Score = 252 bits (617), Expect = 4e-66
Identities = 156/457 (34%), Positives = 207/457 (45%), Gaps = 50/457 (10%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GY + C D+DEC C+ CVN G+F+C+CP G L + C D+
Sbjct: 100 CGKGYSRIKGTQ-CEDIDECEVFPGVCKN-GLCVNTRGSFKCQCPSGMTLDATGRICLDI 157
Query: 154 D-ECGDQRICDHGDCRNTIGSYR---CECKPGYTLRENVCRDVDECSRPRPVCRNGTCEN 209
E R D G +R C C G C +EC C
Sbjct: 158 RLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEEC---EECPMRNTPEYEELCPR 214
Query: 210 LPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADG 269
PG +G D+NEC+ +C +G+CRNT+GSF+C C G+ L ++
Sbjct: 215 GPGFATKEITNG-----KPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEE 269
Query: 270 RNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK---LVGRRCVDRDECKELPY 326
RNC D+DEC P CGR C NT G +EC C G++ ++ + C+D DEC+ P
Sbjct: 270 RNCTDIDECRISPDLCGRG---QCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPL 326
Query: 327 VCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQL-ARP 385
+C GG C N G Y CECP G + + C+D + C E A C R + L +
Sbjct: 327 LCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINE--C--ELSAHLCPNGRCVNLIGKY 382
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNT 445
+C C+ G PD C D+DEC + C C N+
Sbjct: 383 QCACNPGYH--------STPDRL----FC----------VDIDECSIMNGGC-ETFCTNS 419
Query: 446 DGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD- 504
+GS+ C C G+ L PD SC D DEC +P IC G C+N G Y C C GF D
Sbjct: 420 EGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDM 479
Query: 505 QTCVDVDECAEGRASC-TFRCHNTAGSFRCTCPYGYA 540
+TCVDV+EC C + C NT GSF C C GY+
Sbjct: 480 KTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYS 516
Score = 243 bits (595), Expect = 2e-63
Identities = 162/494 (32%), Positives = 228/494 (46%), Gaps = 84/494 (17%)
Query: 7 DQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETK 66
D C + K CC S+G AWG+PC C + P +CG+ Y + +
Sbjct: 63 DGRCEININGATLKSQCCSSLGAAWGSPCTLC--QVDP----ICGKG---YSRIKGTQCE 113
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDV-----------DECSW 115
IDEC++ P +CK G C +T F+C C G D T +C D+ +EC+
Sbjct: 114 DIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTL 173
Query: 116 ---GR---PPC-------RGMAQCVNLP----GAFECRCP--PGY---RLTPSLDECEDV 153
GR C G +C P +E CP PG+ +T +D+
Sbjct: 174 PIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDI 233
Query: 154 DECG-DQRICDHGDCRNTIGSYRCECKPGYTL--RENVCRDVDECSRPRPVCRNGTCENL 210
+EC +C HG CRNTIGS++C C G+ L E C D+DEC +C G C N
Sbjct: 234 NECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 293
Query: 211 PGAYLCHCDDGFKAG--PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTAD 268
PG + C CD+G+++G +C+D++EC+ ++CR G C NT GS+RCEC PG+ L+ +
Sbjct: 294 PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPN 353
Query: 269 GRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPY 326
C D++EC+ H C N C N G Y+C+C G+ R CVD DEC +
Sbjct: 354 ISACIDINECELSAHLC---PNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNG 410
Query: 327 VCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPE 386
C C N G Y C C G+ A+ D+R DE E P
Sbjct: 411 GCE-TFCTNSEGSYECSCQPGF------ALMPDQRSCTDIDECE------------DNPN 451
Query: 387 CCCSEGAAWGRYCERCPAPDSAEFMRICQGG-MGRPNLTQ--DLDECRVRPDVCVGGRCV 443
C G C P E+ +C G M ++ D++EC + P++C+ G C
Sbjct: 452 ICD------GGQCTNIP----GEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCE 501
Query: 444 NTDGSFRCECPDGY 457
NT GSF C C GY
Sbjct: 502 NTKGSFICHCDMGY 515
Score = 230 bits (562), Expect = 2e-59
Identities = 157/498 (31%), Positives = 216/498 (43%), Gaps = 62/498 (12%)
Query: 202 CRNGTCENLPGAYLCHCDDGFKAGPNND-CVDV--NECREGGMVCR-----NG-----RC 248
C NG C+N PG+++C C P C++ C + + R NG +C
Sbjct: 20 CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQC 79
Query: 249 RNTVGS------FRCE----CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
+++G+ C+ C GY+ G C D+DEC+ P C N C NT G
Sbjct: 80 CSSLGAAWGSPCTLCQVDPICGKGYS-RIKGTQCEDIDECEVFPGVC---KNGLCVNTRG 135
Query: 299 GYECSCGAGWKL--VGRRCVD--------RDECKELPYVCAGGECRNFNGGYVCECPAGW 348
++C C +G L GR C+D R E +E AG R+ C A W
Sbjct: 136 SFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAG---RHRMDACCCSVGAAW 192
Query: 349 RFDKTAAVCV---DERKELC--YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
++ + E +ELC + +P EC C
Sbjct: 193 GTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRN-- 250
Query: 404 APDSAEFMRICQGGMG----RPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVL 459
F C G N T D+DECR+ PD+C G+CVNT G F C+C +GY
Sbjct: 251 --TIGSFKCRCDSGFALDSEERNCT-DIDECRISPDLCGRGQCVNTPGDFECKCDEGYES 307
Query: 460 APDGL-SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGR 517
+ +C+D DEC DP +C G C NT G Y C+C PG P+ C+D++EC
Sbjct: 308 GFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSA 367
Query: 518 ASC-TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKC 576
C RC N G ++C C GY D + C DIDEC C C N GSY C C
Sbjct: 368 HLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSC 427
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCI 636
G+ A + +C DI+ECE+ ++C GG C N G + C C GF SED C+
Sbjct: 428 QPGF----ALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCV 483
Query: 637 DRRTGTCYRSL-VSGRCE 653
D ++ +SG CE
Sbjct: 484 DVNECDLNPNICLSGTCE 501
Score = 202 bits (493), Expect = 4e-51
Identities = 129/356 (36%), Positives = 165/356 (46%), Gaps = 50/356 (14%)
Query: 322 KELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQ 381
K L C G C+N G ++CEC + D T +C++ K C+ GRC
Sbjct: 14 KMLSSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGA 73
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ--DLDECRVRPDVCVG 439
+ +CC S GAAWG C C IC G R TQ D+DEC V P VC
Sbjct: 74 TLKSQCCSSLGAAWGSPCTLCQVDP------ICGKGYSRIKGTQCEDIDECEVFPGVCKN 127
Query: 440 GRCVNTDGSFRCECPDGYVLAPDGLSCVDA-----------DECAL--------DPRICG 480
G CVNT GSF+C+CP G L G C+D +EC L D C
Sbjct: 128 GLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCS 187
Query: 481 NGTCSNTRGGYECQ----------C--SPGF-----TQGPDQTCVDVDECAEGRASCTF- 522
G T EC C PGF T G D++EC + CT
Sbjct: 188 VGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNG-KPFFKDINECKMIPSLCTHG 246
Query: 523 RCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYR 581
+C NT GSF+C C G+A+ ++ +C DIDEC P +C C N G + CKC EGY
Sbjct: 247 KCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYE 306
Query: 582 RTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
S +N C DI+EC+ LC GGVC NT+GS+ C+C G + S + + CID
Sbjct: 307 --SGFMMMKN-CMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACID 359
Score = 182 bits (444), Expect = 4e-45
Identities = 83/200 (41%), Positives = 106/200 (53%), Gaps = 4/200 (2%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P LC+ G CH+T ++C C G++ C D++EC C +CV
Sbjct: 318 IDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPN-GRCV 376
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR-- 185
NL G ++C C PGY TP C D+DEC C N+ GSY C C+PG+ L
Sbjct: 377 NLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPD 436
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCR 244
+ C D+DEC +C G C N+PG Y C C DGF A + CVDVNEC +C
Sbjct: 437 QRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICL 496
Query: 245 NGRCRNTVGSFRCECAPGYT 264
+G C NT GSF C C GY+
Sbjct: 497 SGTCENTKGSFICHCDMGYS 516
Score = 164 bits (398), Expect = 1e-39
Identities = 119/388 (30%), Positives = 157/388 (40%), Gaps = 72/388 (18%)
Query: 479 CGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPY 537
C NG C N+ G + C+CS T P +T C+ E +G C T RC
Sbjct: 20 CINGVCKNSPGSFICECSSESTLDPTKTICI---ETIKGT------CWQTVIDGRCEINI 70
Query: 538 GYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDIN 597
A C + P C + + C +GY R Q CEDI+
Sbjct: 71 NGATLKSQC-CSSLGAAWGSP--CTLCQVDPI------CGKGYSRIKGTQ-----CEDID 116
Query: 598 ECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXX 657
ECE +C G+C+NT GSF C C +G G C+D R TC+ C
Sbjct: 117 ECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEEC----- 171
Query: 658 XXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSE-CELCPAPGSPARLDLCTAVN 716
G CCC++GAAWG+E CE CP +P +LC
Sbjct: 172 ---------------TLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPR-- 214
Query: 717 LTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPGLCAPGR-------FRCVCGP 769
F D++EC IP LC G+ F+C C
Sbjct: 215 -------------GPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDS 261
Query: 770 GYRPAGEV--CADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD-EDGANCRDVDEC 825
G+ E C D+DEC + P C + C NT G ++C C GYE NC D+DEC
Sbjct: 262 GFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDEC 321
Query: 826 ERDTHTCQQ-ICSNTEGSYECSCEDGYE 852
+RD C+ +C NTEGSY C C G++
Sbjct: 322 QRDPLLCRGGVCHNTEGSYRCECPPGHQ 349
Score = 100 bits (240), Expect = 2e-20
Identities = 44/115 (38%), Positives = 63/115 (54%), Gaps = 10/115 (8%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHN 797
D++EC LC GR ++C C PGY P C D+DEC++ C+ C N
Sbjct: 359 DINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTN 418
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGY 851
++GSY+C C+ G+ L D +C D+DECE + + C C+N G Y C C DG+
Sbjct: 419 SEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGF 473
Score = 97.1 bits (231), Expect = 2e-19
Identities = 48/122 (39%), Positives = 61/122 (50%), Gaps = 12/122 (9%)
Query: 747 DVDECAAIPGLCA-------PGRFRCVCGPGYRPAGEV---CADVDECAVRPPPC-DQLC 795
D+DEC P LC PG F C C GY + C D+DEC P C +C
Sbjct: 274 DIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVC 333
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKR 854
HNT+GSY C C G++L + + C D++ECE H C C N G Y+C+C GY
Sbjct: 334 HNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHST 393
Query: 855 GD 856
D
Sbjct: 394 PD 395
Score = 94.3 bits (224), Expect = 2e-18
Identities = 45/115 (39%), Positives = 58/115 (50%), Gaps = 10/115 (8%)
Query: 747 DVDECAAIPGLC-------APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ-LCH 796
D+DEC P LC G +RC C PG++ P C D++EC + C C
Sbjct: 317 DIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCV 376
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
N G Y C C GY D C D+DEC C+ C+N+EGSYECSC+ G+
Sbjct: 377 NLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGF 431
Score = 92.3 bits (219), Expect = 7e-18
Identities = 45/115 (39%), Positives = 60/115 (52%), Gaps = 10/115 (8%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQ-LCHN 797
D+DEC+ + G C + G + C C PG+ P C D+DEC P CD C N
Sbjct: 401 DIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTN 460
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGY 851
G Y CLC G+ ED C DV+EC+ + + C C NT+GS+ C C+ GY
Sbjct: 461 IPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGY 515
>AF054502-1|AAC39882.1| 669|Homo sapiens latent transforming growth
factor-beta binding protein 4 protein.
Length = 669
Score = 285 bits (700), Expect = 3e-76
Identities = 174/476 (36%), Positives = 226/476 (47%), Gaps = 36/476 (7%)
Query: 59 NPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQC-GCDHGYEHDNTSHLCRDVDECSWG 116
N +E + +DEC+ L PG C ++P FQC C G+ H + C DVDECS G
Sbjct: 9 NAAGSECEDVDECE--NHLACPGQECVNSPGSFQCRACPSGH-HLHRGR-CTDVDECSSG 64
Query: 117 RPPCRGMAQCVNLPGAFECRCPPGYRLTPS--LDECEDVDECGDQRIC-DHGDCRNTIGS 173
PPC C N G+F C C PGYR PS C DV+EC + C HG+C NT GS
Sbjct: 65 APPCGPHGHCTNTEGSFRCSCAPGYR-APSGRPGPCADVNECLEGDFCFPHGECLNTDGS 123
Query: 174 YRCECKPGYT--LRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDC 230
+ C C PGY R C DVDECS +C++G C N G++ C C G +AGP+ C
Sbjct: 124 FACTCAPGYRPGPRGASCLDVDECSE-EDLCQSGICTNTDGSFECICPPGHRAGPDLASC 182
Query: 231 VDVNECRE-GGMVCRNGRCRNTVGSFRC--ECAPGYTLTADGRNCRDVDECDELPHPCGR 287
+DV+ECRE G +C + RC N+ GS+RC +C PGY +G C DV+EC+ L CG
Sbjct: 183 LDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVNECETLQGVCGA 241
Query: 288 DGNPSCTNTNGGYECSCGAGWK----LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCE 343
C N G + C C + + GR R P
Sbjct: 242 ---ALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGMFPGSQPQAPASPVLPARPPP 298
Query: 344 CPAGWRFDKTAAVCVDERKELCY-DEWEAGRCHRARPLQLARPECCCSEGAAWGRYC--E 400
P R V + CY D C + ECCC+ G WG C +
Sbjct: 299 PPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQ 358
Query: 401 RCPAPDSAEFMRICQGGMG--RP----NLTQDLDECRV-RPDVCVGGRCVNTDGSFRCEC 453
+CP ++AE+ +C G G P +L +D+DEC++ R VC G CVNT + C C
Sbjct: 359 QCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYC 418
Query: 454 PDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCV 508
+GY L C+D DECA + C G C NT G Y C C P G + CV
Sbjct: 419 SNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCV 474
Score = 245 bits (599), Expect = 6e-64
Identities = 171/468 (36%), Positives = 217/468 (46%), Gaps = 41/468 (8%)
Query: 97 GYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECR-CPPGYRLTPSLDECEDVDE 155
G++ + C DVDEC C G +CVN PG+F+CR CP G+ L C DVDE
Sbjct: 5 GFQPNAAGSECEDVDECE-NHLACPGQ-ECVNSPGSFQCRACPSGHHL--HRGRCTDVDE 60
Query: 156 C--GDQRICDHGDCRNTIGSYRCECKPGYTL---RENVCRDVDECSRPRPVCRNGTCENL 210
C G HG C NT GS+RC C PGY R C DV+EC +G C N
Sbjct: 61 CSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNT 120
Query: 211 PGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADG 269
G++ C C G++ GP C+DV+EC E + C++G C NT GSF C C PG+ D
Sbjct: 121 DGSFACTCAPGYRPGPRGASCLDVDECSEEDL-CQSGICTNTDGSFECICPPGHRAGPDL 179
Query: 270 RNCRDVDECDEL-PHPCGRDGNPSCTNTNGGYEC--SCGAGWKLVGR-RCVDRDECKELP 325
+C DVDEC E P C G+ C N+ G Y C C G+ C D +EC+ L
Sbjct: 180 ASCLDVDECRERGPALC---GSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVNECETLQ 236
Query: 326 YVCAGGECRNFNGGYVCECP-AGWRFDKTAAVCVDERKEL-----CYDEWEAGRCHRAR- 378
VC C N G ++C CP + FD CV R + A AR
Sbjct: 237 GVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGMFPGSQPQAPASPVLPARP 296
Query: 379 -PLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC 437
P L R +G G C +A C + R N+T C V
Sbjct: 297 PPPPLPRRPSTPRQGPV-GSGRRECYFDTAAP--DACDNILAR-NVTWQECCCTVGEGWG 352
Query: 438 VGGR---CVNTD-GSFRCECPDGY-VLAPDG-LSC-VDADECAL-DPRICGNGTCSNTRG 489
G R C T+ ++ CP G LAP G LS D DEC L ++C +G C NT
Sbjct: 353 SGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAP 412
Query: 490 GYECQCSPGFTQGPDQ-TCVDVDECAEGRASCT-FRCHNTAGSFRCTC 535
GY C CS G+ + C+D DECA+ +C RC NT GS+ CTC
Sbjct: 413 GYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 460
Score = 182 bits (442), Expect = 6e-45
Identities = 165/528 (31%), Positives = 210/528 (39%), Gaps = 86/528 (16%)
Query: 312 GRRCVDRDECKELPYVCAGGECRNFNGGYVCE-CPAGWRFDKTAAVCVDERKELCYDEWE 370
G C D DEC E C G EC N G + C CP+G + VDE
Sbjct: 12 GSECEDVDEC-ENHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDE---------- 60
Query: 371 AGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDEC 430
C P C +EG+ RC + GRP D++EC
Sbjct: 61 ---CSSGAPPCGPHGHCTNTEGSF------RCSCAPGY------RAPSGRPGPCADVNEC 105
Query: 431 RVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRG 489
+ D C G C+NTDGSF C C GY P G SC+D DEC+ + +C +G C+NT G
Sbjct: 106 -LEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS-EEDLCQSGICTNTDG 163
Query: 490 GYECQCSPGFTQGPD-QTCVDVDECAE-GRASC-TFRCHNTAGSFRCT--CPYGYAVAAD 544
+EC C PG GPD +C+DVDEC E G A C + RC N+ GS+RC C GY +
Sbjct: 164 SFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPE 223
Query: 545 GVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED 604
G C D++EC VC G+ +C+ EG P E C
Sbjct: 224 GT-CDDVNECETLQGVC--------GAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRT 274
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLV-SGRCEPEXXXXXXXX 663
S G+ GS + P+ + RR T + V SGR E
Sbjct: 275 --SAGMF---PGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRE--------CY 321
Query: 664 XXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXX 723
+VT +CCCT+G WGS C + PG+ + +L P
Sbjct: 322 FDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGT----ETAEYQSLCPHGRG 377
Query: 724 XXXXXXXXXXXXXXXXXXLDVFADVDECAAI------PGLC---APGRFRCVCGPGYRPA 774
L + DVDEC G+C APG + C C GY
Sbjct: 378 YLAPSGD-----------LSLRRDVDECQLFRDQVCKSGVCVNTAPG-YSCYCSNGYYYH 425
Query: 775 GE--VCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANC 819
+ C D DECA P C+ C NT GSY C C LD C
Sbjct: 426 TQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC 473
Score = 174 bits (423), Expect = 1e-42
Identities = 92/222 (41%), Positives = 117/222 (52%), Gaps = 13/222 (5%)
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCE-CKPGYTLRENVCRDVDE 194
R P G++ + ECEDVDEC + C +C N+ GS++C C G+ L C DVDE
Sbjct: 1 RGPMGFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDE 60
Query: 195 CSRPRPVCR-NGTCENLPGAYLCHCDDGFKA--GPNNDCVDVNECREGGMVCRNGRCRNT 251
CS P C +G C N G++ C C G++A G C DVNEC EG +G C NT
Sbjct: 61 CSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNT 120
Query: 252 VGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
GSF C CAPGY G +C DVDEC E + G CTNT+G +EC C G +
Sbjct: 121 DGSFACTCAPGYRPGPRGASCLDVDECSE--EDLCQSG--ICTNTDGSFECICPPGHRAG 176
Query: 312 G--RRCVDRDECKEL-PYVCAGGECRNFNGGYVC--ECPAGW 348
C+D DEC+E P +C C N G Y C +C G+
Sbjct: 177 PDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGY 218
Score = 161 bits (391), Expect = 1e-38
Identities = 94/236 (39%), Positives = 122/236 (51%), Gaps = 21/236 (8%)
Query: 415 QGGMG-RPNLT----QDLDECRVRPDVCVGGRCVNTDGSFRCE-CPDGYVLAPDGLSCVD 468
+G MG +PN +D+DEC C G CVN+ GSF+C CP G+ L C D
Sbjct: 1 RGPMGFQPNAAGSECEDVDECENHL-ACPGQECVNSPGSFQCRACPSGHHLHRG--RCTD 57
Query: 469 ADECALDPRICG-NGTCSNTRGGYECQCSPGFT--QGPDQTCVDVDECAEGRASCTF-RC 524
DEC+ CG +G C+NT G + C C+PG+ G C DV+EC EG C
Sbjct: 58 VDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGEC 117
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
NT GSF CTC GY G C D+DEC +E C N GS+ C CP G+R +
Sbjct: 118 LNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHR--A 175
Query: 585 APQDSENACEDINECEEQ-EDLCSGGVCINTDGSFLC--DCDAGFEPSEDGTDCID 637
P + +C D++EC E+ LC C N+ GS+ C DCD G+ +GT C D
Sbjct: 176 GPDLA--SCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CDD 228
Score = 97.5 bits (232), Expect = 2e-19
Identities = 54/123 (43%), Positives = 66/123 (53%), Gaps = 14/123 (11%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYR-PAGEV--CADVDECAVRPPPC--DQ 793
DVDEC++ C P G FRC C PGYR P+G CADV+EC + C
Sbjct: 57 DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNEC-LEGDFCFPHG 115
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C NTDGS+ C C GY GA+C DVDEC + IC+NT+GS+EC C G+
Sbjct: 116 ECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRA 175
Query: 854 RGD 856
D
Sbjct: 176 GPD 178
Score = 97.5 bits (232), Expect = 2e-19
Identities = 54/119 (45%), Positives = 64/119 (53%), Gaps = 13/119 (10%)
Query: 746 ADVDECA----AIP-GLC--APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCH 796
ADV+EC P G C G F C C PGYRP G C DVDEC+ +C
Sbjct: 100 ADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICT 159
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDEC-ERDTHTC-QQICSNTEGSYEC--SCEDGY 851
NTDGS++C+C G+ D A+C DVDEC ER C Q C N+ GSY C C+ GY
Sbjct: 160 NTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGY 218
Score = 96.3 bits (229), Expect = 4e-19
Identities = 64/190 (33%), Positives = 79/190 (41%), Gaps = 17/190 (8%)
Query: 240 GMVCRNGRCRNT-VGSFRCECAPGYTLTADGRNC---RDVDECDELPHPCGRDGNPSCTN 295
G CR +C T ++ C G A + RDVDEC + G C N
Sbjct: 352 GSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSG--VCVN 409
Query: 296 TNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKT 353
T GY C C G+ +R C+D DEC + C GG C N G Y C C D +
Sbjct: 410 TAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGS 469
Query: 354 AAVCV-------DERKELCYDEWEAGR-CHRAR-PLQLARPECCCSEGAAWGRYCERCPA 404
CV D+ +C+ E A C R Q ECCC G AWG C CPA
Sbjct: 470 QRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPA 529
Query: 405 PDSAEFMRIC 414
DS +F +C
Sbjct: 530 QDSDDFEALC 539
Score = 95.5 bits (227), Expect = 7e-19
Identities = 47/133 (35%), Positives = 68/133 (51%), Gaps = 7/133 (5%)
Query: 23 CCCSVGHAWGAPC--EACPPRGSPAHTALCGEKPGEYINPVTNET--KPIDECDIM-PQL 77
CCC+VG WG+ C + CP + + +LC G Y+ P + + + +DEC + Q+
Sbjct: 343 CCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRG-YLAPSGDLSLRRDVDECQLFRDQV 401
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRC 137
CK G C +T G+ C C +GY + C D DEC+ P C G +CVN G++ C C
Sbjct: 402 CKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEG-GRCVNTVGSYHCTC 460
Query: 138 PPGYRLTPSLDEC 150
P L S C
Sbjct: 461 EPPLVLDGSQRRC 473
Score = 84.6 bits (200), Expect = 1e-15
Identities = 49/120 (40%), Positives = 63/120 (52%), Gaps = 14/120 (11%)
Query: 747 DVDECA----AIPGLCA--PGRFRCVCGPGYRPAGEV--CADVDECAVRPPP-C-DQLCH 796
DVDEC+ G+C G F C+C PG+R ++ C DVDEC R P C Q C
Sbjct: 143 DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCE 202
Query: 797 NTDGSYDCL--CRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEK 853
N+ GSY C+ C GY +G C DV+ECE C +C N EGS+ C C + E+
Sbjct: 203 NSPGSYRCVRDCDPGYHAGPEG-TCDDVNECETLQGVCGAALCENVEGSFLCVCPNSPEE 261
Score = 83.8 bits (198), Expect = 2e-15
Identities = 52/126 (41%), Positives = 64/126 (50%), Gaps = 13/126 (10%)
Query: 747 DVDECA---AIPGL-C--APGRFRC-VCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHN 797
DVDEC A PG C +PG F+C C G+ C DVDEC+ PPC C N
Sbjct: 17 DVDECENHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTN 76
Query: 798 TDGSYDCLCRTGYELDEDGAN-CRDVDEC-ERDTHTCQQICSNTEGSYECSCEDGYE--K 853
T+GS+ C C GY C DV+EC E D C NT+GS+ C+C GY
Sbjct: 77 TEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGP 136
Query: 854 RGDACV 859
RG +C+
Sbjct: 137 RGASCL 142
Score = 82.6 bits (195), Expect = 5e-15
Identities = 57/199 (28%), Positives = 80/199 (40%), Gaps = 21/199 (10%)
Query: 523 RCHNT-AGSFRCTCPYG---YAVAADGVHCRDIDEC-VQEPRVCPHA-CENVVGSYICKC 576
+C T ++ CP+G A + D RD+DEC + +VC C N Y C C
Sbjct: 359 QCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYC 418
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCI 636
GY + + C D +EC ++E C GG C+NT GS+ C C+ C+
Sbjct: 419 SNGYYYHTQRLE----CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCV 474
Query: 637 DRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSE 696
+ + +L G C E T +CCC G AWG +
Sbjct: 475 SNESQSLDDNL--GVCWQEVGADLVCSHPRLDR---------QATYTECCCLYGEAWGMD 523
Query: 697 CELCPAPGSPARLDLCTAV 715
C LCPA S LC +
Sbjct: 524 CALCPAQDSDDFEALCNVL 542
Score = 69.7 bits (163), Expect = 4e-11
Identities = 39/90 (43%), Positives = 47/90 (52%), Gaps = 8/90 (8%)
Query: 768 GP-GYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDC-LCRTGYELDEDGANCRDVD 823
GP G++P AG C DVDEC Q C N+ GS+ C C +G+ L C DVD
Sbjct: 2 GPMGFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQCRACPSGHHLHR--GRCTDVD 59
Query: 824 ECERDTHTC--QQICSNTEGSYECSCEDGY 851
EC C C+NTEGS+ CSC GY
Sbjct: 60 ECSSGAPPCGPHGHCTNTEGSFRCSCAPGY 89
Score = 63.3 bits (147), Expect = 4e-09
Identities = 36/90 (40%), Positives = 44/90 (48%), Gaps = 6/90 (6%)
Query: 765 CVCGPGY-RPAGEVCA--DVDECAV-RPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANC 819
C G GY P+G++ DVDEC + R C +C NT Y C C GY C
Sbjct: 372 CPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLEC 431
Query: 820 RDVDECERDTHTCQ-QICSNTEGSYECSCE 848
D DEC + C+ C NT GSY C+CE
Sbjct: 432 IDNDECADEEPACEGGRCVNTVGSYHCTCE 461
Score = 57.6 bits (133), Expect = 2e-07
Identities = 32/88 (36%), Positives = 42/88 (47%), Gaps = 5/88 (5%)
Query: 54 PGEYINPVTNETKPIDEC-DIMPQLCKPGTCHDTPTGFQC--GCDHGYEHDNTSHLCRDV 110
PG P +DEC + P LC C ++P ++C CD GY H C DV
Sbjct: 171 PGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGY-HAGPEGTCDDV 229
Query: 111 DECSWGRPPCRGMAQCVNLPGAFECRCP 138
+EC + C G A C N+ G+F C CP
Sbjct: 230 NECETLQGVC-GAALCENVEGSFLCVCP 256
Score = 47.6 bits (108), Expect = 2e-04
Identities = 22/53 (41%), Positives = 26/53 (49%)
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRI 478
D DEC C GGRCVNT GS+ C C VL CV + +LD +
Sbjct: 433 DNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL 485
Score = 42.3 bits (95), Expect = 0.007
Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 809 GYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC-SCEDGYEKRGDAC 858
G++ + G+ C DVDECE Q C N+ GS++C +C G+ C
Sbjct: 5 GFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQCRACPSGHHLHRGRC 55
Score = 40.3 bits (90), Expect = 0.028
Identities = 17/39 (43%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 23 CCCSVGHAWGAPCEACPPRGSPAHTALCGE-KPGEYINP 60
CCC G AWG C CP + S ALC +P Y P
Sbjct: 512 CCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPP 550
Score = 37.5 bits (83), Expect = 0.20
Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 6/65 (9%)
Query: 793 QLCHNTD-GSYDCLCR--TGYELDEDGANCR-DVDECE--RDTHTCQQICSNTEGSYECS 846
Q C T+ Y LC GY + R DVDEC+ RD +C NT Y C
Sbjct: 358 QQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY 417
Query: 847 CEDGY 851
C +GY
Sbjct: 418 CSNGY 422
>AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
protein.
Length = 2471
Score = 258 bits (632), Expect = 6e-68
Identities = 238/820 (29%), Positives = 331/820 (40%), Gaps = 113/820 (13%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD-VDECSWGRPPCRGMAQC 126
ID+C P L C D P G++C C G+ T LC + +D C PC QC
Sbjct: 533 IDDCSSTPCL-NGAKCIDHPNGYECQCATGF----TGVLCEENIDNCD--PDPCHH-GQC 584
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
+ ++ C C PGY D+ +DEC + G C + + Y+C C+PG T
Sbjct: 585 QDGIDSYTCICNPGYMGAICSDQ---IDECYSSPCLNDGRCIDLVNGYQCNCQPG-TSGV 640
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
N + D+C+ P C +G C + Y C C GF N +D++EC CR G
Sbjct: 641 NCEINFDDCAS-NP-CIHGICMDGINRYSCVCSPGFTGQRCN--IDIDECASNP--CRKG 694
Query: 247 R-CRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
C N V FRC C G +C V+EC L +PC GN CT GY+C C
Sbjct: 695 ATCINGVNGFRCICPEG----PHHPSCYSQVNEC--LSNPCIH-GN--CTGGLSGYKCLC 745
Query: 305 GAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDE-- 360
AGW VG C VD++EC P C GG C N GY C C G++ V +DE
Sbjct: 746 DAGW--VGINCEVDKNECLSNP--CQNGGTCDNLVNGYRCTCKKGFK-GYNCQVNIDECA 800
Query: 361 -----RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP----APDSAEFM 411
+ C+D+ CH P C CE +P+ +
Sbjct: 801 SNPCLNQGTCFDDISGYTCHCVLPY--TGKNCQTVLAPCSPNPCENAAVCKESPNFESYT 858
Query: 412 RICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCV-DA 469
+C G T D+DEC +P C+ G C NT GS+ CECP G+ G+ C D
Sbjct: 859 CLCAPGWQGQRCTIDIDECISKP--CMNHGLCHNTQGSYMCECPPGF----SGMDCEEDI 912
Query: 470 DECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTA 528
D+C +P C NG +C + + C C PGFT QT D++EC C +
Sbjct: 913 DDCLANP--CQNGGSCMDGVNTFSCLCLPGFTGDKCQT--DMNECLSEPCKNGGTCSDYV 968
Query: 529 GSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQ 587
S+ C C G+ DGVHC + I+EC + C + + S+ C CP G+ +
Sbjct: 969 NSYTCKCQAGF----DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFC-- 1022
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGT--DCIDR----RTG 641
+INEC L + G C++ G++ C C G+ T + R G
Sbjct: 1023 -----LHEINECSSHPCL-NEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKG 1076
Query: 642 TCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQC-----CCTLGAAWGSE 696
TC + +C G + + C C G +
Sbjct: 1077 TCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQ 1136
Query: 697 CELCPAPGS--PARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAI 754
C L GS +LD C A N ++ +VDEC
Sbjct: 1137 CPL-GYTGSYCEEQLDEC-ASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQ 1194
Query: 755 P----GLCAP--GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPC--DQLCHNTDGSYDCL 805
P G C F+C C PG R G +C + +D+CA R P C C + G Y C
Sbjct: 1195 PCQNGGTCIDLVNHFKCSCPPGTR--GLLCEENIDDCA-RGPHCLNGGQCMDRIGGYSCR 1251
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC 845
C G+ + CE D + C ++EGS +C
Sbjct: 1252 CLPGFA----------GERCEGDINECLSNPCSSEGSLDC 1281
Score = 227 bits (556), Expect = 1e-58
Identities = 189/617 (30%), Positives = 272/617 (44%), Gaps = 94/617 (15%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQC 126
I+EC P + G C D FQC C G+ T +C+ D+D+CS PC A+C
Sbjct: 495 INECQSNPCV-NNGQCVDKVNRFQCLCPPGF----TGPVCQIDIDDCS--STPCLNGAKC 547
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
++ P +EC+C G+ T L E E++D C D C HG C++ I SY C C PGY
Sbjct: 548 IDHPNGYECQCATGF--TGVLCE-ENIDNC-DPDPCHHGQCQDGIDSYTCICNPGYM--G 601
Query: 187 NVCRD-VDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN 245
+C D +DEC P +G C +L Y C+C G +G N + ++ ++C C +
Sbjct: 602 AICSDQIDECYSS-PCLNDGRCIDLVNGYQCNCQPG-TSGVNCE-INFDDCASNP--CIH 656
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
G C + + + C C+PG+T G+ C D+DEC +PC R G +C N G+ C C
Sbjct: 657 GICMDGINRYSCVCSPGFT----GQRCNIDIDECAS--NPC-RKG-ATCINGVNGFRCIC 708
Query: 305 GAGWKLVGRRCVDR-DECKELPYVCAGGECRNFNGGYVCECPAGW-----RFDKTAAVCV 358
G C + +EC P C G C GY C C AGW DK +
Sbjct: 709 PEGPHHPS--CYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSN 764
Query: 359 D-ERKELCYDEWEAGRC-----HRARPLQLARPEC----CCSEGAAW---GRYCERCPAP 405
+ C + RC + Q+ EC C ++G + Y C P
Sbjct: 765 PCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLP 824
Query: 406 DSAEFMRICQGGMG--RPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDG 463
+ + CQ + PN ++ C+ P+ S+ C C G+ G
Sbjct: 825 YTG---KNCQTVLAPCSPNPCENAAVCKESPNF----------ESYTCLCAPGW----QG 867
Query: 464 LSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF 522
C +D DEC P + +G C NT+G Y C+C PGF+ G D D+D+C
Sbjct: 868 QRCTIDIDECISKPCM-NHGLCHNTQGSYMCECPPGFS-GMDCE-EDIDDCLANPCQNGG 924
Query: 523 RCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + +F C C G+ G C+ D++EC+ EP C + V SY CKC G+
Sbjct: 925 SCMDGVNTFSCLCLPGFT----GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF- 979
Query: 582 RTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPS---EDGTDCIDR 638
D + +INEC E +GG C++ SF C C GF S + +C
Sbjct: 980 ------DGVHCENNINECTE-SSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSH 1032
Query: 639 ---RTGTCYRSLVSGRC 652
GTC L + RC
Sbjct: 1033 PCLNEGTCVDGLGTYRC 1049
Score = 221 bits (541), Expect = 6e-57
Identities = 179/583 (30%), Positives = 246/583 (42%), Gaps = 72/583 (12%)
Query: 92 CGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLP-GAFECRCPPGYRLTPSLDEC 150
C C G+ ++ + C RP C C L +EC C G+ + EC
Sbjct: 90 CRCASGFTGEDCQYSTSH--PCFVSRP-CLNGGTCHMLSRDTYECTCQVGF----TGKEC 142
Query: 151 EDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGTCEN 209
+ D C + C + C+C G+T ++ C DV+EC P GTC N
Sbjct: 143 QWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQK--CETDVNECDIPGHCQHGGTCLN 200
Query: 210 LPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVG-SFRCECAPGYTLTAD 268
LPG+Y C C GF G D + V C V G CR T +F C C PG+ +
Sbjct: 201 LPGSYQCQCPQGF-TGQYCDSLYV-PCAPSPCV-NGGTCRQTGDFTFECNCLPGF----E 253
Query: 269 GRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV-DRDECKELPY 326
G C R++D+C H C G C + Y C C W G+ C D DEC P
Sbjct: 254 GSTCERNIDDCPN--HRCQNGG--VCVDGVNTYNCRCPPQW--TGQFCTEDVDECLLQPN 307
Query: 327 VCA-GGECRNFNGGYVCECPAGWRFDKTA------AVCVDERKELCYDEWEAGRC---HR 376
C GG C N NGGY C C GW D + A C D + C
Sbjct: 308 ACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEG 367
Query: 377 ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRV-RPD 435
L + C S G C+ P + +++ C G + T+D+DEC + +
Sbjct: 368 KAGLLCHLDDACISNPCHKGALCDTNPL--NGQYICTCPQGYKGADCTEDVDECAMANSN 425
Query: 436 VCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGN-GTCSNTRGGYE 492
C G+CVNTDG+F CEC GY G C +D +EC DP C N TC + GG+
Sbjct: 426 PCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDP--CQNDATCLDKIGGFT 479
Query: 493 CQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DI 551
C C PGF +G ++++EC +C + F+C CP G+ G C+ DI
Sbjct: 480 CLCMPGF-KGV-HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFT----GPVCQIDI 533
Query: 552 DECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVC 611
D+C P + C + Y C+C G+ E+I+ C+ D C G C
Sbjct: 534 DDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCE-------ENIDNCD--PDPCHHGQC 584
Query: 612 INTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS--LVSGRC 652
+ S+ C C+ G+ G C D + CY S L GRC
Sbjct: 585 QDGIDSYTCICNPGYM----GAICSD-QIDECYSSPCLNDGRC 622
Score = 221 bits (539), Expect = 1e-56
Identities = 201/672 (29%), Positives = 286/672 (42%), Gaps = 96/672 (14%)
Query: 21 YLCCCSVGHAWGAPC---EACPPRGSPAHT-ALCGEKP--GEYINPVTNE------TKPI 68
+ C C G A G C +AC +P H ALC P G+YI T+ +
Sbjct: 360 FSCMCPEGKA-GLLCHLDDACI--SNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDV 416
Query: 69 DECDIM-PQLCK-PGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
DEC + C+ G C +T F C C GY D++EC PC+ A C
Sbjct: 417 DECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE---MDINECH--SDPCQNDATC 471
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
++ G F C C PG++ CE +++EC ++G C + + ++C C PG+T
Sbjct: 472 LDKIGGFTCLCMPGFKGV----HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFT-- 525
Query: 186 ENVCR-DVDECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC 243
VC+ D+D+CS C NG C + P Y C C GF + +D C C
Sbjct: 526 GPVCQIDIDDCSSTP--CLNGAKCIDHPNGYECQCATGFTGVLCEENID--NCDPDP--C 579
Query: 244 RNGRCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGGYEC 302
+G+C++ + S+ C C PGY G C D +DEC PC DG C + GY+C
Sbjct: 580 HHGQCQDGIDSYTCICNPGYM----GAICSDQIDEC--YSSPCLNDGR--CIDLVNGYQC 631
Query: 303 SCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE- 360
+C G G C ++ D+C P C G C + Y C C G+ + + +DE
Sbjct: 632 NCQPGTS--GVNCEINFDDCASNP--CIHGICMDGINRYSCVCSPGFTGQR-CNIDIDEC 686
Query: 361 -----RK-ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYC--ERCPAPDSAEFMR 412
RK C + RC P P C C C S +
Sbjct: 687 ASNPCRKGATCINGVNGFRC--ICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSG-YKC 743
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDAD 470
+C G N D +EC P C GG C N +RC C G+ G +C V+ D
Sbjct: 744 LCDAGWVGINCEVDKNECLSNP--CQNGGTCDNLVNGYRCTCKKGF----KGYNCQVNID 797
Query: 471 ECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAG- 529
ECA +P + GTC + GY C C +T QT + C+ C +
Sbjct: 798 ECASNPCL-NQGTCFDDISGYTCHCVLPYTGKNCQTVLA--PCSPNPCENAAVCKESPNF 854
Query: 530 -SFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQ 587
S+ C C G+ G C DIDEC+ +P + C N GSY+C+CP G+ +
Sbjct: 855 ESYTCLCAPGW----QGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGF----SGM 906
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTD---CID---RRTG 641
D E EDI++C +GG C++ +F C C GF + TD C+ + G
Sbjct: 907 DCE---EDIDDC-LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGG 962
Query: 642 TCYRSLVSGRCE 653
TC + S C+
Sbjct: 963 TCSDYVNSYTCK 974
Score = 220 bits (538), Expect = 1e-56
Identities = 241/888 (27%), Positives = 341/888 (38%), Gaps = 127/888 (14%)
Query: 20 KYLCCCSVGHAWGAPCEA----CPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMP 75
++ C C G G CE C G H C PG Y CD +
Sbjct: 165 QFSCKCLTGFT-GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTG-QYCDSLY 222
Query: 76 QLCKP------GTCHDTPT-GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
C P GTC T F+C C G+E R++D+C R C+ CV+
Sbjct: 223 VPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCE---RNIDDCPNHR--CQNGGVCVD 277
Query: 129 LPGAFECRCPPGYRLTPSLDEC-EDVDECGDQ-RICDHGD-CRNTIGSYRCECKPGYTLR 185
+ CRCPP + + C EDVDEC Q C +G C N G Y C C G++
Sbjct: 278 GVNTYNCRCPPQW----TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWS-G 332
Query: 186 ENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGP----NNDCVDVNECREGG 240
++ ++D+C+ C G TC + ++ C C +G KAG ++ C+ N C +G
Sbjct: 333 DDCSENIDDCAFAS--CTPGSTCIDRVASFSCMCPEG-KAGLLCHLDDACIS-NPCHKGA 388
Query: 241 MVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDEL-PHPCGRDGNPSCTNTNG 298
+ N G + C C GY G +C DVDEC +PC G C NT+G
Sbjct: 389 LCDTNP----LNGQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGK--CVNTDG 438
Query: 299 GYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRFDKTAAV 356
+ C C G+ G RC +D +EC P C C + GG+ C C G++
Sbjct: 439 AFHCECLKGY--AGPRCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFKGVHCELE 494
Query: 357 CVDERKELCYDEWEA----GRCHRARPLQLARPEC------CCSEGAAWGRYCERCPAPD 406
+ + C + + R P P C C S G C P+
Sbjct: 495 INECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKC--IDHPN 552
Query: 407 SAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
E C G +++D C PD C G+C + S+ C C GY+ G C
Sbjct: 553 GYECQ--CATGFTGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYM----GAIC 604
Query: 467 VDA-DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
D DEC P + +G C + GY+C C PG T G + ++ D+CA C
Sbjct: 605 SDQIDECYSSPCL-NDGRCIDLVNGYQCNCQPG-TSGVNCE-INFDDCASNPCIHGI-CM 660
Query: 526 NTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
+ + C C G+ G C DIDEC P C N V + C CPEG S
Sbjct: 661 DGINRYSCVCSPGFT----GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPS 716
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF---EPSEDGTDCID---R 638
+NEC C G C + C CDAG+ D +C+ +
Sbjct: 717 C-------YSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQ 767
Query: 639 RTGTCYRSLVSG-RCEPEXXXXXXXXXXXXXXXXXX-----XXXXGHVTKAQCCCTLGAA 692
GTC +LV+G RC + ++ C C L
Sbjct: 768 NGGTC-DNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYT 826
Query: 693 WGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECA 752
G C+ AP SP + +P D+DEC
Sbjct: 827 -GKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTI-------DIDECI 878
Query: 753 AIP----GLC--APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCL 805
+ P GLC G + C C PG+ +G C D+D+C P C + ++ CL
Sbjct: 879 SKPCMNHGLCHNTQGSYMCECPPGF--SGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCL 936
Query: 806 CRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
C G+ G C+ D++EC + CS+ SY C C+ G++
Sbjct: 937 CLPGFT----GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD 980
Score = 205 bits (501), Expect = 5e-52
Identities = 177/575 (30%), Positives = 257/575 (44%), Gaps = 90/575 (15%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDV-DECSWGRPPCRGMAQC 126
IDEC P L GTC D +G+ C C Y N C+ V CS PC A C
Sbjct: 796 IDECASNPCL-NQGTCFDDISGYTCHCVLPYTGKN----CQTVLAPCSPN--PCENAAVC 848
Query: 127 VNLPG--AFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYT 183
P ++ C C PG++ C D+DEC + +HG C NT GSY CEC PG++
Sbjct: 849 KESPNFESYTCLCAPGWQG----QRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFS 904
Query: 184 LRENVC-RDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGM 241
+ C D+D+C P G+C + + C C GF + C D+NEC
Sbjct: 905 GMD--CEEDIDDC-LANPCQNGGSCMDGVNTFSCLCLPGF---TGDKCQTDMNECL--SE 956
Query: 242 VCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGG 299
C+N G C + V S+ C+C G+ DG +C +++EC E C G +C +
Sbjct: 957 PCKNGGTCSDYVNSYTCKCQAGF----DGVHCENNINECTE--SSCFNGG--TCVDGINS 1008
Query: 300 YECSCGAGWKLVGRRCV-DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV 358
+ C C G+ G C+ + +EC P + G C + G Y C CP G+ +
Sbjct: 1009 FSCLCPVGF--TGSFCLHEINECSSHPCL-NEGTCVDGLGTYRCSCPLGYTGKNCQTLVN 1065
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
+ C ++ G C + + A +C C G A G YC+ P+ + + + G+
Sbjct: 1066 LCSRSPCKNK---GTCVQKK----AESQCLCPSGWA-GAYCD---VPNVSCDIAASRRGV 1114
Query: 419 GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD-ADECALDPR 477
+L Q G C+N + C+CP GY G C + DECA +P
Sbjct: 1115 LVEHLCQH------------SGVCINAGNTHYCQCPLGYT----GSYCEEQLDECASNP- 1157
Query: 478 ICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCP 536
C +G TCS+ GGY C+C PG+ QG + +VDEC C + F+C+CP
Sbjct: 1158 -CQHGATCSDFIGGYRCECVPGY-QGVNCE-YEVDECQNQPCQNGGTCIDLVNHFKCSCP 1214
Query: 537 YGYAVAADGVHCRD-IDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENAC 593
G G+ C + ID+C + P C + C + +G Y C+C G+ + C
Sbjct: 1215 PG----TRGLLCEENIDDCARGPH-CLNGGQCMDRIGGYSCRCLPGF--------AGERC 1261
Query: 594 E-DINECEEQEDLCSGGV-CINTDGSFLCDCDAGF 626
E DINEC G + CI +LC C + F
Sbjct: 1262 EGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF 1296
Score = 198 bits (482), Expect = 9e-50
Identities = 184/673 (27%), Positives = 265/673 (39%), Gaps = 99/673 (14%)
Query: 21 YLCCCSVGHA-----WGAPCEACPPRGSPAHTALCGEKPGEYINPVTNET--KPIDECDI 73
Y C C VG W C + P T + + + + T + ++ECDI
Sbjct: 129 YECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 188
Query: 74 MPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG-A 132
GTC + P +QC C G+ T C D PC C
Sbjct: 189 PGHCQHGGTCLNLPGSYQCQCPQGF----TGQYC-DSLYVPCAPSPCVNGGTCRQTGDFT 243
Query: 133 FECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRD 191
FEC C PG+ + CE ++D+C + R + G C + + +Y C C P +T + D
Sbjct: 244 FECNCLPGFEGS----TCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWT-GQFCTED 298
Query: 192 VDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVD-VNECREGGMVCRNG-RC 248
VDEC C+N GTC N G Y C C +G+ +DC + +++C C G C
Sbjct: 299 VDECLLQPNACQNGGTCANRNGGYGCVCVNGWS---GDDCSENIDDCAFAS--CTPGSTC 353
Query: 249 RNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
+ V SF C C G G C D C + +PC + NG Y C+C G+
Sbjct: 354 IDRVASFSCMCPEGKA----GLLCHLDDAC--ISNPCHKGALCDTNPLNGQYICTCPQGY 407
Query: 309 KLVGRRCV-DRDECKEL-PYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
K G C D DEC C G+C N +G + CEC G+ R E+
Sbjct: 408 K--GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY---------AGPRCEMD 456
Query: 366 YDEWEAGRCHRARPL--QLARPECCCSEGAAWGRYCE----RC---PAPDSAE------- 409
+E + C ++ C C G G +CE C P ++ +
Sbjct: 457 INECHSDPCQNDATCLDKIGGFTCLCMPGFK-GVHCELEINECQSNPCVNNGQCVDKVNR 515
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
F +C G P D+D+C P C+ G +C++ + C+C G+ G+ C +
Sbjct: 516 FQCLCPPGFTGPVCQIDIDDCSSTP--CLNGAKCIDHPNGYECQCATGFT----GVLCEE 569
Query: 469 -ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHN 526
D C DP C +G C + Y C C+PG+ C D +DEC RC +
Sbjct: 570 NIDNC--DPDPCHHGQCQDGIDSYTCICNPGYM---GAICSDQIDECYSSPCLNDGRCID 624
Query: 527 TAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTS 584
++C C G GV+C + D+C P C H C + + Y C C G+
Sbjct: 625 LVNGYQCNCQPG----TSGVNCEINFDDCASNP--CIHGICMDGINRYSCVCSPGF---- 674
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG-FEPS--EDGTDCIDRRT- 640
+ DI+EC G CIN F C C G PS +C+
Sbjct: 675 ---TGQRCNIDIDEC-ASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCI 730
Query: 641 -GTCYRSLVSGRC 652
G C L +C
Sbjct: 731 HGNCTGGLSGYKC 743
Score = 196 bits (477), Expect = 4e-49
Identities = 172/616 (27%), Positives = 254/616 (41%), Gaps = 102/616 (16%)
Query: 75 PQLCK-PGTCHDTPT--GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG 131
P C+ C ++P + C C G++ + D+DEC PC C N G
Sbjct: 839 PNPCENAAVCKESPNFESYTCLCAPGWQGQRCTI---DIDECI--SKPCMNHGLCHNTQG 893
Query: 132 AFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRD 191
++ C CPPG+ +D ED+D+C + G C + + ++ C C PG+T + D
Sbjct: 894 SYMCECPPGFS---GMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFT-GDKCQTD 949
Query: 192 VDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RC 248
++EC S P C+NG TC + +Y C C GF + ++NEC E C NG C
Sbjct: 950 MNECLSEP---CKNGGTCSDYVNSYTCKCQAGFDGVHCEN--NINECTESS--CFNGGTC 1002
Query: 249 RNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
+ + SF C C G+T G C +++EC HPC +G +C + G Y CSC G
Sbjct: 1003 VDGINSFSCLCPVGFT----GSFCLHEINECSS--HPCLNEG--TCVDGLGTYRCSCPLG 1054
Query: 308 WKLVGRRCVDR-DECKELPYVCAG-GECRNFNGGYVCECPAGWRF------DKTAAVCVD 359
+ G+ C + C P C G C C CP+GW + + +
Sbjct: 1055 Y--TGKNCQTLVNLCSRSP--CKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAAS 1110
Query: 360 ER----KELCYDEW---EAGRCHRAR-PLQLARPEC------CCSEGAAWGRYCERCPAP 405
R + LC AG H + PL C C S G C
Sbjct: 1111 RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGG 1170
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGL 464
E C G N ++DEC+ +P C GG C++ F+C CP G GL
Sbjct: 1171 YRCE----CVPGYQGVNCEYEVDECQNQP--CQNGGTCIDLVNHFKCSCPPG----TRGL 1220
Query: 465 SCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRASC-- 520
C + D+CA P G C + GGY C+C PGF + C D++EC S
Sbjct: 1221 LCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA---GERCEGDINECLSNPCSSEG 1277
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPHAC---ENVVGSYICKC 576
+ C + C C + G HC +D C Q P + C N+ +IC+C
Sbjct: 1278 SLDCIQLTNDYLCVCRSAFT----GRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRC 1333
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC------DCDAG--FEP 628
P G+ +++C + +C + E C++T C DC++G P
Sbjct: 1334 PPGFSGARC----QSSCGQV-KCRKGEQ------CVHTASGPRCFCPSPRDCESGCASSP 1382
Query: 629 SEDGTDCIDRRTGTCY 644
+ G C +R Y
Sbjct: 1383 CQHGGSCHPQRQPPYY 1398
Score = 182 bits (442), Expect = 6e-45
Identities = 193/682 (28%), Positives = 275/682 (40%), Gaps = 101/682 (14%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCE--ACPPRGSPAHTALCGEKPGEYINPVTNETKP 67
C A G T LC ++ + PC C G ++T +C PG Y+ + ++
Sbjct: 556 CQCATGF--TGVLCEENIDNCDPDPCHHGQCQD-GIDSYTCICN--PG-YMGAICSDQ-- 607
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P L G C D G+QC C G N + D+C+ P G+ C+
Sbjct: 608 IDECYSSPCL-NDGRCIDLVNGYQCNCQPGTSGVNCEI---NFDDCA-SNPCIHGI--CM 660
Query: 128 NLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
+ + C C PG+ + C D+DEC C N + +RC C G
Sbjct: 661 DGINRYSCVCSPGF----TGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG-PHHP 715
Query: 187 NVCRDVDEC-SRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN 245
+ V+EC S P C +G C Y C CD G+ G N + VD NEC C+N
Sbjct: 716 SCYSQVNECLSNP---CIHGNCTGGLSGYKCLCDAGW-VGINCE-VDKNECLSNP--CQN 768
Query: 246 G-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECS 303
G C N V +RC C G+ G NC+ ++DEC +PC G +C + GY C
Sbjct: 769 GGTCDNLVNGYRCTCKKGFK----GYNCQVNIDECAS--NPCLNQG--TCFDDISGYTCH 820
Query: 304 CGAGWKLVGRRCVD-RDECKELPYVCAG--GECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
C + G+ C C P A E NF Y C C GW+ + + +DE
Sbjct: 821 CVLPY--TGKNCQTVLAPCSPNPCENAAVCKESPNFES-YTCLCAPGWQGQR-CTIDIDE 876
Query: 361 R-KELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCER----C---PAPDSAE--- 409
+ C + G CH + + C C G + G CE C P +
Sbjct: 877 CISKPCMNH---GLCHNTQGSYM----CECPPGFS-GMDCEEDIDDCLANPCQNGGSCMD 928
Query: 410 ----FMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGL 464
F +C G D++EC P C GG C + S+ C+C G+ DG+
Sbjct: 929 GVNTFSCLCLPGFTGDKCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGF----DGV 982
Query: 465 SCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRASCTF 522
C + +EC + GTC + + C C GFT C+ +++EC+
Sbjct: 983 HCENNINECT-ESSCFNGGTCVDGINSFSCLCPVGFT---GSFCLHEINECSSHPCLNEG 1038
Query: 523 RCHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + G++RC+CP GY G +C+ ++ C + P C C CP G+
Sbjct: 1039 TCVDGLGTYRCSCPLGYT----GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW- 1093
Query: 582 RTSAPQDSENACEDINECEEQ---EDLCS-GGVCINTDGSFLCDCDAGFEPS---EDGTD 634
A D N DI E LC GVCIN + C C G+ S E +
Sbjct: 1094 -AGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDE 1152
Query: 635 CID---RRTGTCYRSLVSGRCE 653
C + TC + RCE
Sbjct: 1153 CASNPCQHGATCSDFIGGYRCE 1174
Score = 177 bits (430), Expect = 2e-43
Identities = 159/549 (28%), Positives = 217/549 (39%), Gaps = 85/549 (15%)
Query: 112 ECSWGRPPCRGMAQCVNLP-GAFECRCPPGYRLTPSLDE-CEDVDECGDQRICDHGDC-- 167
+C G PC CV G C+CP G+ L E C+ D C R + G C
Sbjct: 27 QCRDGYEPCVNEGMCVTYHNGTGYCKCPEGF-----LGEYCQHRDPCEKNRCQNGGTCVA 81
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLP-GAYLCHCDDGFKAGP 226
+ +G C C G+T + C RP GTC L Y C C GF
Sbjct: 82 QAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGF---T 138
Query: 227 NNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHP 284
+C + C C NG C F C+C G+T G+ C DV+ECD +P
Sbjct: 139 GKECQWTDACL--SHPCANGSTCTTVANQFSCKCLTGFT----GQKCETDVNECD-IPGH 191
Query: 285 CGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNG-GYVC 342
C G +C N G Y+C C G+ G+ C D P C GG CR + C
Sbjct: 192 CQHGG--TCLNLPGSYQCQCPQGF--TGQYC-DSLYVPCAPSPCVNGGTCRQTGDFTFEC 246
Query: 343 ECPAGWRFD--------------KTAAVCVDERKEL---CYDEWEAGRCHRARPLQLARP 385
C G+ + VCVD C +W C L +P
Sbjct: 247 NCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP 306
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNT 445
C + G R + + +C G + ++++D+C G C++
Sbjct: 307 NACQNGGTCANR---------NGGYGCVCVNGWSGDDCSENIDDCAF-ASCTPGSTCIDR 356
Query: 446 DGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNT---RGGYECQCSPGFTQG 502
SF C CP+G GL C D C +P C G +T G Y C C G+ +G
Sbjct: 357 VASFSCMCPEGKA----GLLCHLDDACISNP--CHKGALCDTNPLNGQYICTCPQGY-KG 409
Query: 503 PDQTCVDVDECAEGRAS-CTF--RCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEP 558
D T DVDECA ++ C +C NT G+F C C GYA G C DI+EC +P
Sbjct: 410 ADCT-EDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDP 464
Query: 559 RVCPHACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGS 617
C + +G + C C G++ CE +INEC + + G C++
Sbjct: 465 CQNDATCLDKIGGFTCLCMPGFKGVH--------CELEINEC-QSNPCVNNGQCVDKVNR 515
Query: 618 FLCDCDAGF 626
F C C GF
Sbjct: 516 FQCLCPPGF 524
Score = 134 bits (324), Expect = 1e-30
Identities = 127/442 (28%), Positives = 177/442 (40%), Gaps = 56/442 (12%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
GTC D F C C G+ T C +++ECS PC CV+ G + C CP
Sbjct: 1000 GTCVDGINSFSCLCPVGF----TGSFCLHEINECS--SHPCLNEGTCVDGLGTYRCSCPL 1053
Query: 140 GYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYRCECKPG----YTLRENVCRDVDE 194
GY + C+ V+ C + G C +C C G Y NV D+
Sbjct: 1054 GY----TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAA 1109
Query: 195 CSRP---RPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CR 249
R +C++ G C N + C C G+ + +D EC C++G C
Sbjct: 1110 SRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLD--ECASNP--CQHGATCS 1165
Query: 250 NTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
+ +G +RCEC PGY G NC +VDEC PC G +C + ++CSC G
Sbjct: 1166 DFIGGYRCECVPGY----QGVNCEYEVDECQN--QPCQNGG--TCIDLVNHFKCSCPPGT 1217
Query: 309 KLVGRRCVDR-DECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYD 367
+ G C + D+C P+ GG+C + GGY C C G+ ++ + C
Sbjct: 1218 R--GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSS 1275
Query: 368 EWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM-GRPNLTQD 426
E C +QL C A GR+CE D M GG + D
Sbjct: 1276 EGSLD-C-----IQLTNDYLCVCRSAFTGRHCETFV--DVCPQMPCLNGGTCAVASNMPD 1327
Query: 427 LDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV-----DADE-CALDPRICG 480
CR P G RC ++ G +C + V G C D + CA P G
Sbjct: 1328 GFICRCPPGFS-GARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHG 1386
Query: 481 NGTCSNTRGG--YECQCSPGFT 500
G+C R Y CQC+P F+
Sbjct: 1387 -GSCHPQRQPPYYSCQCAPPFS 1407
Score = 112 bits (269), Expect = 6e-24
Identities = 116/442 (26%), Positives = 159/442 (35%), Gaps = 58/442 (13%)
Query: 439 GGRCVNTD--GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSN-TRGGYECQC 495
GG CV G C C G+ + + C + GTC +R YEC C
Sbjct: 76 GGTCVAQAMLGKATCRCASGFT--GEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC 133
Query: 496 SPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDEC 554
GFT + C D C + C A F C C G+ G C D++EC
Sbjct: 134 QVGFT---GKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFT----GQKCETDVNEC 186
Query: 555 VQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCI 612
P C H C N+ GSY C+CP+G+ + C+ + +GG C
Sbjct: 187 -DIPGHCQHGGTCLNLPGSYQCQCPQGF--------TGQYCDSLYVPCAPSPCVNGGTCR 237
Query: 613 NT-DGSFLCDCDAGFEPS---EDGTDCIDRRT---GTCYRSL--VSGRCEPEXXXXXXXX 663
T D +F C+C GFE S + DC + R G C + + RC P+
Sbjct: 238 QTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTE 297
Query: 664 XXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSEC-ELCPAPGSPARLDLCTAVNLTPXXX 722
G C +G C +D C + TP
Sbjct: 298 DVDECLLQPNACQNGGT-----CANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGST 352
Query: 723 XXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP----GLCAP----GRFRCVCGPGYRPA 774
L D D C + P LC G++ C C GY+ A
Sbjct: 353 CIDRVASFSCMCPEGKAGLL-CHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGA 410
Query: 775 GEVCADVDECAV-RPPPCDQL--CHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTH 830
+ DVDECA+ PC+ C NTDG++ C C GY G C D++EC D
Sbjct: 411 -DCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDPC 465
Query: 831 TCQQICSNTEGSYECSCEDGYE 852
C + G + C C G++
Sbjct: 466 QNDATCLDKIGGFTCLCMPGFK 487
Score = 64.5 bits (150), Expect = 2e-09
Identities = 34/98 (34%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 820
+ C+C PG++ G+ C D+DEC +P LCHNT GSY C C G+ G +C
Sbjct: 857 YTCLCAPGWQ--GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGF----SGMDCEE 910
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
D+D+C + C + ++ C C G+ GD C
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGF--TGDKC 946
Score = 60.5 bits (140), Expect = 2e-08
Identities = 35/108 (32%), Positives = 51/108 (47%), Gaps = 12/108 (11%)
Query: 756 GLCAPG--RFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY 810
G+C G + C C P + G+ C DVDEC ++P C C N +G Y C+C G+
Sbjct: 273 GVCVDGVNTYNCRCPPQW--TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGW 330
Query: 811 ELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
D+ N +D+C + T C + S+ C C +G K G C
Sbjct: 331 SGDDCSEN---IDDCAFASCTPGSTCIDRVASFSCMCPEG--KAGLLC 373
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/118 (30%), Positives = 55/118 (46%), Gaps = 14/118 (11%)
Query: 742 LDVFADVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQL 794
+D D+D+C A P G C G F C+C PG+ G+ C D++EC P
Sbjct: 906 MDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGF--TGDKCQTDMNECLSEPCKNGGT 963
Query: 795 CHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C + SY C C+ G+ DG +C +++EC + C + S+ C C G+
Sbjct: 964 CSDYVNSYTCKCQAGF----DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGF 1017
Score = 52.4 bits (120), Expect = 7e-06
Identities = 36/107 (33%), Positives = 46/107 (42%), Gaps = 12/107 (11%)
Query: 756 GLC--APGRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G+C A C C GY G C + +DECA P C + G Y C C GY+
Sbjct: 1124 GVCINAGNTHYCQCPLGY--TGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQ- 1180
Query: 813 DEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
G NC +VDEC+ C + ++CSC G RG C
Sbjct: 1181 ---GVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG--TRGLLC 1222
Score = 52.0 bits (119), Expect = 9e-06
Identities = 69/272 (25%), Positives = 92/272 (33%), Gaps = 41/272 (15%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
ID+C P G C D G+ C C G+ + D++EC G C+
Sbjct: 1226 IDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE---GDINECLSNPCSSEGSLDCI 1282
Query: 128 NLPGAFECRCPPGYRLTPSLDECED-VDECGDQRICDHGDC---RNTIGSYRCECKPGYT 183
L + C C + + CE VD C + G C N + C C PG+
Sbjct: 1283 QLTNDYLCVCRSAF----TGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGF- 1337
Query: 184 LRENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMV 242
+ R C + + CR G C + C C + C + C+ GG
Sbjct: 1338 ---SGARCQSSCGQVK--CRKGEQCVHTASGPRCFCPS--PRDCESGCAS-SPCQHGGS- 1388
Query: 243 CRNGR--------CRNTVGSFRCE--CAPGYT--LTADGRNCRDVDE---CDEL--PHPC 285
C R C RCE AP T T + C D CDE H C
Sbjct: 1389 CHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHAC 1448
Query: 286 GRDGNP-SCTNTNGGYECSCGAG-WKLVGRRC 315
DG S T N CS W + +C
Sbjct: 1449 QWDGGDCSLTMENPWANCSSPLPCWDYINNQC 1480
Score = 42.7 bits (96), Expect = 0.005
Identities = 33/115 (28%), Positives = 53/115 (46%), Gaps = 18/115 (15%)
Query: 747 DVDECAAIP----GLCAP--GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTD 799
D++EC + P G C+ + C C G+ G C + ++EC C +
Sbjct: 949 DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD--GVHCENNINECTESSCFNGGTCVDGI 1006
Query: 800 GSYDCLCRTGYELDEDGANC-RDVDECERDTHTC--QQICSNTEGSYECSCEDGY 851
S+ CLC G+ G+ C +++EC +H C + C + G+Y CSC GY
Sbjct: 1007 NSFSCLCPVGFT----GSFCLHEINECS--SHPCLNEGTCVDGLGTYRCSCPLGY 1055
Score = 41.9 bits (94), Expect = 0.009
Identities = 35/122 (28%), Positives = 49/122 (40%), Gaps = 18/122 (14%)
Query: 747 DVDECAAIP----GLC--APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D +EC + P G C +RC C G++ G C ++DECA P C +
Sbjct: 757 DKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK--GYNCQVNIDECASNPCLNQGTCFDDI 814
Query: 800 GSYDCLCRTGYELDEDGANCRDV-DECERDTHTCQQICSNTEG--SYECSCEDGYEKRGD 856
Y C C Y G NC+ V C + +C + SY C C G++ G
Sbjct: 815 SGYTCHCVLPY----TGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ--GQ 868
Query: 857 AC 858
C
Sbjct: 869 RC 870
>AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
protein.
Length = 2471
Score = 258 bits (632), Expect = 6e-68
Identities = 238/820 (29%), Positives = 331/820 (40%), Gaps = 113/820 (13%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD-VDECSWGRPPCRGMAQC 126
ID+C P L C D P G++C C G+ T LC + +D C PC QC
Sbjct: 533 IDDCSSTPCL-NGAKCIDHPNGYECQCATGF----TGVLCEENIDNCD--PDPCHH-GQC 584
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
+ ++ C C PGY D+ +DEC + G C + + Y+C C+PG T
Sbjct: 585 QDGIDSYTCICNPGYMGAICSDQ---IDECYSSPCLNDGRCIDLVNGYQCNCQPG-TSGV 640
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
N + D+C+ P C +G C + Y C C GF N +D++EC CR G
Sbjct: 641 NCEINFDDCAS-NP-CIHGICMDGINRYSCVCSPGFTGQRCN--IDIDECASNP--CRKG 694
Query: 247 R-CRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
C N V FRC C G +C V+EC L +PC GN CT GY+C C
Sbjct: 695 ATCINGVNGFRCICPEG----PHHPSCYSQVNEC--LSNPCIH-GN--CTGGLSGYKCLC 745
Query: 305 GAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDE-- 360
AGW VG C VD++EC P C GG C N GY C C G++ V +DE
Sbjct: 746 DAGW--VGINCEVDKNECLSNP--CQNGGTCDNLVNGYRCTCKKGFK-GYNCQVNIDECA 800
Query: 361 -----RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP----APDSAEFM 411
+ C+D+ CH P C CE +P+ +
Sbjct: 801 SNPCLNQGTCFDDISGYTCHCVLPY--TGKNCQTVLAPCSPNPCENAAVCKESPNFESYT 858
Query: 412 RICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCV-DA 469
+C G T D+DEC +P C+ G C NT GS+ CECP G+ G+ C D
Sbjct: 859 CLCAPGWQGQRCTIDIDECISKP--CMNHGLCHNTQGSYMCECPPGF----SGMDCEEDI 912
Query: 470 DECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTA 528
D+C +P C NG +C + + C C PGFT QT D++EC C +
Sbjct: 913 DDCLANP--CQNGGSCMDGVNTFSCLCLPGFTGDKCQT--DMNECLSEPCKNGGTCSDYV 968
Query: 529 GSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQ 587
S+ C C G+ DGVHC + I+EC + C + + S+ C CP G+ +
Sbjct: 969 NSYTCKCQAGF----DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFC-- 1022
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGT--DCIDR----RTG 641
+INEC L + G C++ G++ C C G+ T + R G
Sbjct: 1023 -----LHEINECSSHPCL-NEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKG 1076
Query: 642 TCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQC-----CCTLGAAWGSE 696
TC + +C G + + C C G +
Sbjct: 1077 TCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQ 1136
Query: 697 CELCPAPGS--PARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAI 754
C L GS +LD C A N ++ +VDEC
Sbjct: 1137 CPL-GYTGSYCEEQLDEC-ASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQ 1194
Query: 755 P----GLCAP--GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPC--DQLCHNTDGSYDCL 805
P G C F+C C PG R G +C + +D+CA R P C C + G Y C
Sbjct: 1195 PCQNGGTCIDLVNHFKCSCPPGTR--GLLCEENIDDCA-RGPHCLNGGQCMDRIGGYSCR 1251
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC 845
C G+ + CE D + C ++EGS +C
Sbjct: 1252 CLPGFA----------GERCEGDINECLSNPCSSEGSLDC 1281
Score = 227 bits (556), Expect = 1e-58
Identities = 189/617 (30%), Positives = 272/617 (44%), Gaps = 94/617 (15%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQC 126
I+EC P + G C D FQC C G+ T +C+ D+D+CS PC A+C
Sbjct: 495 INECQSNPCV-NNGQCVDKVNRFQCLCPPGF----TGPVCQIDIDDCS--STPCLNGAKC 547
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
++ P +EC+C G+ T L E E++D C D C HG C++ I SY C C PGY
Sbjct: 548 IDHPNGYECQCATGF--TGVLCE-ENIDNC-DPDPCHHGQCQDGIDSYTCICNPGYM--G 601
Query: 187 NVCRD-VDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN 245
+C D +DEC P +G C +L Y C+C G +G N + ++ ++C C +
Sbjct: 602 AICSDQIDECYSS-PCLNDGRCIDLVNGYQCNCQPG-TSGVNCE-INFDDCASNP--CIH 656
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
G C + + + C C+PG+T G+ C D+DEC +PC R G +C N G+ C C
Sbjct: 657 GICMDGINRYSCVCSPGFT----GQRCNIDIDECAS--NPC-RKG-ATCINGVNGFRCIC 708
Query: 305 GAGWKLVGRRCVDR-DECKELPYVCAGGECRNFNGGYVCECPAGW-----RFDKTAAVCV 358
G C + +EC P C G C GY C C AGW DK +
Sbjct: 709 PEGPHHPS--CYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSN 764
Query: 359 D-ERKELCYDEWEAGRC-----HRARPLQLARPEC----CCSEGAAW---GRYCERCPAP 405
+ C + RC + Q+ EC C ++G + Y C P
Sbjct: 765 PCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLP 824
Query: 406 DSAEFMRICQGGMG--RPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDG 463
+ + CQ + PN ++ C+ P+ S+ C C G+ G
Sbjct: 825 YTG---KNCQTVLAPCSPNPCENAAVCKESPNF----------ESYTCLCAPGW----QG 867
Query: 464 LSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF 522
C +D DEC P + +G C NT+G Y C+C PGF+ G D D+D+C
Sbjct: 868 QRCTIDIDECISKPCM-NHGLCHNTQGSYMCECPPGFS-GMDCE-EDIDDCLANPCQNGG 924
Query: 523 RCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + +F C C G+ G C+ D++EC+ EP C + V SY CKC G+
Sbjct: 925 SCMDGVNTFSCLCLPGFT----GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF- 979
Query: 582 RTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPS---EDGTDCIDR 638
D + +INEC E +GG C++ SF C C GF S + +C
Sbjct: 980 ------DGVHCENNINECTE-SSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSH 1032
Query: 639 ---RTGTCYRSLVSGRC 652
GTC L + RC
Sbjct: 1033 PCLNEGTCVDGLGTYRC 1049
Score = 221 bits (541), Expect = 6e-57
Identities = 179/583 (30%), Positives = 246/583 (42%), Gaps = 72/583 (12%)
Query: 92 CGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLP-GAFECRCPPGYRLTPSLDEC 150
C C G+ ++ + C RP C C L +EC C G+ + EC
Sbjct: 90 CRCASGFTGEDCQYSTSH--PCFVSRP-CLNGGTCHMLSRDTYECTCQVGF----TGKEC 142
Query: 151 EDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGTCEN 209
+ D C + C + C+C G+T ++ C DV+EC P GTC N
Sbjct: 143 QWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQK--CETDVNECDIPGHCQHGGTCLN 200
Query: 210 LPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVG-SFRCECAPGYTLTAD 268
LPG+Y C C GF G D + V C V G CR T +F C C PG+ +
Sbjct: 201 LPGSYQCQCPQGF-TGQYCDSLYV-PCAPSPCV-NGGTCRQTGDFTFECNCLPGF----E 253
Query: 269 GRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV-DRDECKELPY 326
G C R++D+C H C G C + Y C C W G+ C D DEC P
Sbjct: 254 GSTCERNIDDCPN--HRCQNGG--VCVDGVNTYNCRCPPQW--TGQFCTEDVDECLLQPN 307
Query: 327 VCA-GGECRNFNGGYVCECPAGWRFDKTA------AVCVDERKELCYDEWEAGRC---HR 376
C GG C N NGGY C C GW D + A C D + C
Sbjct: 308 ACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEG 367
Query: 377 ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRV-RPD 435
L + C S G C+ P + +++ C G + T+D+DEC + +
Sbjct: 368 KAGLLCHLDDACISNPCHKGALCDTNPL--NGQYICTCPQGYKGADCTEDVDECAMANSN 425
Query: 436 VCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGN-GTCSNTRGGYE 492
C G+CVNTDG+F CEC GY G C +D +EC DP C N TC + GG+
Sbjct: 426 PCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDP--CQNDATCLDKIGGFT 479
Query: 493 CQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DI 551
C C PGF +G ++++EC +C + F+C CP G+ G C+ DI
Sbjct: 480 CLCMPGF-KGV-HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFT----GPVCQIDI 533
Query: 552 DECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVC 611
D+C P + C + Y C+C G+ E+I+ C+ D C G C
Sbjct: 534 DDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCE-------ENIDNCD--PDPCHHGQC 584
Query: 612 INTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS--LVSGRC 652
+ S+ C C+ G+ G C D + CY S L GRC
Sbjct: 585 QDGIDSYTCICNPGYM----GAICSD-QIDECYSSPCLNDGRC 622
Score = 221 bits (539), Expect = 1e-56
Identities = 201/672 (29%), Positives = 286/672 (42%), Gaps = 96/672 (14%)
Query: 21 YLCCCSVGHAWGAPC---EACPPRGSPAHT-ALCGEKP--GEYINPVTNE------TKPI 68
+ C C G A G C +AC +P H ALC P G+YI T+ +
Sbjct: 360 FSCMCPEGKA-GLLCHLDDACI--SNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDV 416
Query: 69 DECDIM-PQLCK-PGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
DEC + C+ G C +T F C C GY D++EC PC+ A C
Sbjct: 417 DECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE---MDINECH--SDPCQNDATC 471
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
++ G F C C PG++ CE +++EC ++G C + + ++C C PG+T
Sbjct: 472 LDKIGGFTCLCMPGFKGV----HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFT-- 525
Query: 186 ENVCR-DVDECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC 243
VC+ D+D+CS C NG C + P Y C C GF + +D C C
Sbjct: 526 GPVCQIDIDDCSSTP--CLNGAKCIDHPNGYECQCATGFTGVLCEENID--NCDPDP--C 579
Query: 244 RNGRCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGGYEC 302
+G+C++ + S+ C C PGY G C D +DEC PC DG C + GY+C
Sbjct: 580 HHGQCQDGIDSYTCICNPGYM----GAICSDQIDEC--YSSPCLNDGR--CIDLVNGYQC 631
Query: 303 SCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE- 360
+C G G C ++ D+C P C G C + Y C C G+ + + +DE
Sbjct: 632 NCQPGTS--GVNCEINFDDCASNP--CIHGICMDGINRYSCVCSPGFTGQR-CNIDIDEC 686
Query: 361 -----RK-ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYC--ERCPAPDSAEFMR 412
RK C + RC P P C C C S +
Sbjct: 687 ASNPCRKGATCINGVNGFRC--ICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSG-YKC 743
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDAD 470
+C G N D +EC P C GG C N +RC C G+ G +C V+ D
Sbjct: 744 LCDAGWVGINCEVDKNECLSNP--CQNGGTCDNLVNGYRCTCKKGF----KGYNCQVNID 797
Query: 471 ECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAG- 529
ECA +P + GTC + GY C C +T QT + C+ C +
Sbjct: 798 ECASNPCL-NQGTCFDDISGYTCHCVLPYTGKNCQTVLA--PCSPNPCENAAVCKESPNF 854
Query: 530 -SFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQ 587
S+ C C G+ G C DIDEC+ +P + C N GSY+C+CP G+ +
Sbjct: 855 ESYTCLCAPGW----QGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGF----SGM 906
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTD---CID---RRTG 641
D E EDI++C +GG C++ +F C C GF + TD C+ + G
Sbjct: 907 DCE---EDIDDC-LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGG 962
Query: 642 TCYRSLVSGRCE 653
TC + S C+
Sbjct: 963 TCSDYVNSYTCK 974
Score = 220 bits (538), Expect = 1e-56
Identities = 241/888 (27%), Positives = 341/888 (38%), Gaps = 127/888 (14%)
Query: 20 KYLCCCSVGHAWGAPCEA----CPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMP 75
++ C C G G CE C G H C PG Y CD +
Sbjct: 165 QFSCKCLTGFT-GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTG-QYCDSLY 222
Query: 76 QLCKP------GTCHDTPT-GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
C P GTC T F+C C G+E R++D+C R C+ CV+
Sbjct: 223 VPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCE---RNIDDCPNHR--CQNGGVCVD 277
Query: 129 LPGAFECRCPPGYRLTPSLDEC-EDVDECGDQ-RICDHGD-CRNTIGSYRCECKPGYTLR 185
+ CRCPP + + C EDVDEC Q C +G C N G Y C C G++
Sbjct: 278 GVNTYNCRCPPQW----TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWS-G 332
Query: 186 ENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGP----NNDCVDVNECREGG 240
++ ++D+C+ C G TC + ++ C C +G KAG ++ C+ N C +G
Sbjct: 333 DDCSENIDDCAFAS--CTPGSTCIDRVASFSCMCPEG-KAGLLCHLDDACIS-NPCHKGA 388
Query: 241 MVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDEL-PHPCGRDGNPSCTNTNG 298
+ N G + C C GY G +C DVDEC +PC G C NT+G
Sbjct: 389 LCDTNP----LNGQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGK--CVNTDG 438
Query: 299 GYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRFDKTAAV 356
+ C C G+ G RC +D +EC P C C + GG+ C C G++
Sbjct: 439 AFHCECLKGY--AGPRCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFKGVHCELE 494
Query: 357 CVDERKELCYDEWEA----GRCHRARPLQLARPEC------CCSEGAAWGRYCERCPAPD 406
+ + C + + R P P C C S G C P+
Sbjct: 495 INECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKC--IDHPN 552
Query: 407 SAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
E C G +++D C PD C G+C + S+ C C GY+ G C
Sbjct: 553 GYECQ--CATGFTGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYM----GAIC 604
Query: 467 VDA-DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
D DEC P + +G C + GY+C C PG T G + ++ D+CA C
Sbjct: 605 SDQIDECYSSPCL-NDGRCIDLVNGYQCNCQPG-TSGVNCE-INFDDCASNPCIHGI-CM 660
Query: 526 NTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
+ + C C G+ G C DIDEC P C N V + C CPEG S
Sbjct: 661 DGINRYSCVCSPGFT----GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPS 716
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF---EPSEDGTDCID---R 638
+NEC C G C + C CDAG+ D +C+ +
Sbjct: 717 C-------YSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQ 767
Query: 639 RTGTCYRSLVSG-RCEPEXXXXXXXXXXXXXXXXXX-----XXXXGHVTKAQCCCTLGAA 692
GTC +LV+G RC + ++ C C L
Sbjct: 768 NGGTC-DNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYT 826
Query: 693 WGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECA 752
G C+ AP SP + +P D+DEC
Sbjct: 827 -GKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTI-------DIDECI 878
Query: 753 AIP----GLC--APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCL 805
+ P GLC G + C C PG+ +G C D+D+C P C + ++ CL
Sbjct: 879 SKPCMNHGLCHNTQGSYMCECPPGF--SGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCL 936
Query: 806 CRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
C G+ G C+ D++EC + CS+ SY C C+ G++
Sbjct: 937 CLPGFT----GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD 980
Score = 205 bits (501), Expect = 5e-52
Identities = 177/575 (30%), Positives = 257/575 (44%), Gaps = 90/575 (15%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDV-DECSWGRPPCRGMAQC 126
IDEC P L GTC D +G+ C C Y N C+ V CS PC A C
Sbjct: 796 IDECASNPCL-NQGTCFDDISGYTCHCVLPYTGKN----CQTVLAPCSPN--PCENAAVC 848
Query: 127 VNLPG--AFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYT 183
P ++ C C PG++ C D+DEC + +HG C NT GSY CEC PG++
Sbjct: 849 KESPNFESYTCLCAPGWQG----QRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFS 904
Query: 184 LRENVC-RDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGM 241
+ C D+D+C P G+C + + C C GF + C D+NEC
Sbjct: 905 GMD--CEEDIDDC-LANPCQNGGSCMDGVNTFSCLCLPGF---TGDKCQTDMNECL--SE 956
Query: 242 VCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGG 299
C+N G C + V S+ C+C G+ DG +C +++EC E C G +C +
Sbjct: 957 PCKNGGTCSDYVNSYTCKCQAGF----DGVHCENNINECTE--SSCFNGG--TCVDGINS 1008
Query: 300 YECSCGAGWKLVGRRCV-DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV 358
+ C C G+ G C+ + +EC P + G C + G Y C CP G+ +
Sbjct: 1009 FSCLCPVGF--TGSFCLHEINECSSHPCL-NEGTCVDGLGTYRCSCPLGYTGKNCQTLVN 1065
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
+ C ++ G C + + A +C C G A G YC+ P+ + + + G+
Sbjct: 1066 LCSRSPCKNK---GTCVQKK----AESQCLCPSGWA-GAYCD---VPNVSCDIAASRRGV 1114
Query: 419 GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD-ADECALDPR 477
+L Q G C+N + C+CP GY G C + DECA +P
Sbjct: 1115 LVEHLCQH------------SGVCINAGNTHYCQCPLGYT----GSYCEEQLDECASNP- 1157
Query: 478 ICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCP 536
C +G TCS+ GGY C+C PG+ QG + +VDEC C + F+C+CP
Sbjct: 1158 -CQHGATCSDFIGGYRCECVPGY-QGVNCE-YEVDECQNQPCQNGGTCIDLVNHFKCSCP 1214
Query: 537 YGYAVAADGVHCRD-IDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENAC 593
G G+ C + ID+C + P C + C + +G Y C+C G+ + C
Sbjct: 1215 PG----TRGLLCEENIDDCARGPH-CLNGGQCMDRIGGYSCRCLPGF--------AGERC 1261
Query: 594 E-DINECEEQEDLCSGGV-CINTDGSFLCDCDAGF 626
E DINEC G + CI +LC C + F
Sbjct: 1262 EGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF 1296
Score = 198 bits (482), Expect = 9e-50
Identities = 184/673 (27%), Positives = 265/673 (39%), Gaps = 99/673 (14%)
Query: 21 YLCCCSVGHA-----WGAPCEACPPRGSPAHTALCGEKPGEYINPVTNET--KPIDECDI 73
Y C C VG W C + P T + + + + T + ++ECDI
Sbjct: 129 YECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 188
Query: 74 MPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG-A 132
GTC + P +QC C G+ T C D PC C
Sbjct: 189 PGHCQHGGTCLNLPGSYQCQCPQGF----TGQYC-DSLYVPCAPSPCVNGGTCRQTGDFT 243
Query: 133 FECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRD 191
FEC C PG+ + CE ++D+C + R + G C + + +Y C C P +T + D
Sbjct: 244 FECNCLPGFEGS----TCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWT-GQFCTED 298
Query: 192 VDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVD-VNECREGGMVCRNG-RC 248
VDEC C+N GTC N G Y C C +G+ +DC + +++C C G C
Sbjct: 299 VDECLLQPNACQNGGTCANRNGGYGCVCVNGWS---GDDCSENIDDCAFAS--CTPGSTC 353
Query: 249 RNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
+ V SF C C G G C D C + +PC + NG Y C+C G+
Sbjct: 354 IDRVASFSCMCPEGKA----GLLCHLDDAC--ISNPCHKGALCDTNPLNGQYICTCPQGY 407
Query: 309 KLVGRRCV-DRDECKEL-PYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
K G C D DEC C G+C N +G + CEC G+ R E+
Sbjct: 408 K--GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY---------AGPRCEMD 456
Query: 366 YDEWEAGRCHRARPL--QLARPECCCSEGAAWGRYCE----RC---PAPDSAE------- 409
+E + C ++ C C G G +CE C P ++ +
Sbjct: 457 INECHSDPCQNDATCLDKIGGFTCLCMPGFK-GVHCELEINECQSNPCVNNGQCVDKVNR 515
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
F +C G P D+D+C P C+ G +C++ + C+C G+ G+ C +
Sbjct: 516 FQCLCPPGFTGPVCQIDIDDCSSTP--CLNGAKCIDHPNGYECQCATGFT----GVLCEE 569
Query: 469 -ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHN 526
D C DP C +G C + Y C C+PG+ C D +DEC RC +
Sbjct: 570 NIDNC--DPDPCHHGQCQDGIDSYTCICNPGYM---GAICSDQIDECYSSPCLNDGRCID 624
Query: 527 TAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTS 584
++C C G GV+C + D+C P C H C + + Y C C G+
Sbjct: 625 LVNGYQCNCQPG----TSGVNCEINFDDCASNP--CIHGICMDGINRYSCVCSPGF---- 674
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG-FEPS--EDGTDCIDRRT- 640
+ DI+EC G CIN F C C G PS +C+
Sbjct: 675 ---TGQRCNIDIDEC-ASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCI 730
Query: 641 -GTCYRSLVSGRC 652
G C L +C
Sbjct: 731 HGNCTGGLSGYKC 743
Score = 196 bits (477), Expect = 4e-49
Identities = 172/616 (27%), Positives = 254/616 (41%), Gaps = 102/616 (16%)
Query: 75 PQLCK-PGTCHDTPT--GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG 131
P C+ C ++P + C C G++ + D+DEC PC C N G
Sbjct: 839 PNPCENAAVCKESPNFESYTCLCAPGWQGQRCTI---DIDECI--SKPCMNHGLCHNTQG 893
Query: 132 AFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRD 191
++ C CPPG+ +D ED+D+C + G C + + ++ C C PG+T + D
Sbjct: 894 SYMCECPPGFS---GMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFT-GDKCQTD 949
Query: 192 VDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RC 248
++EC S P C+NG TC + +Y C C GF + ++NEC E C NG C
Sbjct: 950 MNECLSEP---CKNGGTCSDYVNSYTCKCQAGFDGVHCEN--NINECTESS--CFNGGTC 1002
Query: 249 RNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
+ + SF C C G+T G C +++EC HPC +G +C + G Y CSC G
Sbjct: 1003 VDGINSFSCLCPVGFT----GSFCLHEINECSS--HPCLNEG--TCVDGLGTYRCSCPLG 1054
Query: 308 WKLVGRRCVDR-DECKELPYVCAG-GECRNFNGGYVCECPAGWRF------DKTAAVCVD 359
+ G+ C + C P C G C C CP+GW + + +
Sbjct: 1055 Y--TGKNCQTLVNLCSRSP--CKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAAS 1110
Query: 360 ER----KELCYDEW---EAGRCHRAR-PLQLARPEC------CCSEGAAWGRYCERCPAP 405
R + LC AG H + PL C C S G C
Sbjct: 1111 RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGG 1170
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGL 464
E C G N ++DEC+ +P C GG C++ F+C CP G GL
Sbjct: 1171 YRCE----CVPGYQGVNCEYEVDECQNQP--CQNGGTCIDLVNHFKCSCPPG----TRGL 1220
Query: 465 SCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRASC-- 520
C + D+CA P G C + GGY C+C PGF + C D++EC S
Sbjct: 1221 LCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA---GERCEGDINECLSNPCSSEG 1277
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPHAC---ENVVGSYICKC 576
+ C + C C + G HC +D C Q P + C N+ +IC+C
Sbjct: 1278 SLDCIQLTNDYLCVCRSAFT----GRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRC 1333
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC------DCDAG--FEP 628
P G+ +++C + +C + E C++T C DC++G P
Sbjct: 1334 PPGFSGARC----QSSCGQV-KCRKGEQ------CVHTASGPRCFCPSPRDCESGCASSP 1382
Query: 629 SEDGTDCIDRRTGTCY 644
+ G C +R Y
Sbjct: 1383 CQHGGSCHPQRQPPYY 1398
Score = 182 bits (442), Expect = 6e-45
Identities = 193/682 (28%), Positives = 275/682 (40%), Gaps = 101/682 (14%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCE--ACPPRGSPAHTALCGEKPGEYINPVTNETKP 67
C A G T LC ++ + PC C G ++T +C PG Y+ + ++
Sbjct: 556 CQCATGF--TGVLCEENIDNCDPDPCHHGQCQD-GIDSYTCICN--PG-YMGAICSDQ-- 607
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P L G C D G+QC C G N + D+C+ P G+ C+
Sbjct: 608 IDECYSSPCL-NDGRCIDLVNGYQCNCQPGTSGVNCEI---NFDDCA-SNPCIHGI--CM 660
Query: 128 NLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
+ + C C PG+ + C D+DEC C N + +RC C G
Sbjct: 661 DGINRYSCVCSPGF----TGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG-PHHP 715
Query: 187 NVCRDVDEC-SRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN 245
+ V+EC S P C +G C Y C CD G+ G N + VD NEC C+N
Sbjct: 716 SCYSQVNECLSNP---CIHGNCTGGLSGYKCLCDAGW-VGINCE-VDKNECLSNP--CQN 768
Query: 246 G-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECS 303
G C N V +RC C G+ G NC+ ++DEC +PC G +C + GY C
Sbjct: 769 GGTCDNLVNGYRCTCKKGFK----GYNCQVNIDECAS--NPCLNQG--TCFDDISGYTCH 820
Query: 304 CGAGWKLVGRRCVD-RDECKELPYVCAG--GECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
C + G+ C C P A E NF Y C C GW+ + + +DE
Sbjct: 821 CVLPY--TGKNCQTVLAPCSPNPCENAAVCKESPNFES-YTCLCAPGWQGQR-CTIDIDE 876
Query: 361 R-KELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCER----C---PAPDSAE--- 409
+ C + G CH + + C C G + G CE C P +
Sbjct: 877 CISKPCMNH---GLCHNTQGSYM----CECPPGFS-GMDCEEDIDDCLANPCQNGGSCMD 928
Query: 410 ----FMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGL 464
F +C G D++EC P C GG C + S+ C+C G+ DG+
Sbjct: 929 GVNTFSCLCLPGFTGDKCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGF----DGV 982
Query: 465 SCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRASCTF 522
C + +EC + GTC + + C C GFT C+ +++EC+
Sbjct: 983 HCENNINECT-ESSCFNGGTCVDGINSFSCLCPVGFT---GSFCLHEINECSSHPCLNEG 1038
Query: 523 RCHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + G++RC+CP GY G +C+ ++ C + P C C CP G+
Sbjct: 1039 TCVDGLGTYRCSCPLGYT----GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW- 1093
Query: 582 RTSAPQDSENACEDINECEEQ---EDLCS-GGVCINTDGSFLCDCDAGFEPS---EDGTD 634
A D N DI E LC GVCIN + C C G+ S E +
Sbjct: 1094 -AGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDE 1152
Query: 635 CID---RRTGTCYRSLVSGRCE 653
C + TC + RCE
Sbjct: 1153 CASNPCQHGATCSDFIGGYRCE 1174
Score = 177 bits (430), Expect = 2e-43
Identities = 159/549 (28%), Positives = 217/549 (39%), Gaps = 85/549 (15%)
Query: 112 ECSWGRPPCRGMAQCVNLP-GAFECRCPPGYRLTPSLDE-CEDVDECGDQRICDHGDC-- 167
+C G PC CV G C+CP G+ L E C+ D C R + G C
Sbjct: 27 QCRDGYEPCVNEGMCVTYHNGTGYCKCPEGF-----LGEYCQHRDPCEKNRCQNGGTCVA 81
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLP-GAYLCHCDDGFKAGP 226
+ +G C C G+T + C RP GTC L Y C C GF
Sbjct: 82 QAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGF---T 138
Query: 227 NNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHP 284
+C + C C NG C F C+C G+T G+ C DV+ECD +P
Sbjct: 139 GKECQWTDACL--SHPCANGSTCTTVANQFSCKCLTGFT----GQKCETDVNECD-IPGH 191
Query: 285 CGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNG-GYVC 342
C G +C N G Y+C C G+ G+ C D P C GG CR + C
Sbjct: 192 CQHGG--TCLNLPGSYQCQCPQGF--TGQYC-DSLYVPCAPSPCVNGGTCRQTGDFTFEC 246
Query: 343 ECPAGWRFD--------------KTAAVCVDERKEL---CYDEWEAGRCHRARPLQLARP 385
C G+ + VCVD C +W C L +P
Sbjct: 247 NCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP 306
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNT 445
C + G R + + +C G + ++++D+C G C++
Sbjct: 307 NACQNGGTCANR---------NGGYGCVCVNGWSGDDCSENIDDCAF-ASCTPGSTCIDR 356
Query: 446 DGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNT---RGGYECQCSPGFTQG 502
SF C CP+G GL C D C +P C G +T G Y C C G+ +G
Sbjct: 357 VASFSCMCPEGKA----GLLCHLDDACISNP--CHKGALCDTNPLNGQYICTCPQGY-KG 409
Query: 503 PDQTCVDVDECAEGRAS-CTF--RCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEP 558
D T DVDECA ++ C +C NT G+F C C GYA G C DI+EC +P
Sbjct: 410 ADCT-EDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDP 464
Query: 559 RVCPHACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGS 617
C + +G + C C G++ CE +INEC + + G C++
Sbjct: 465 CQNDATCLDKIGGFTCLCMPGFKGVH--------CELEINEC-QSNPCVNNGQCVDKVNR 515
Query: 618 FLCDCDAGF 626
F C C GF
Sbjct: 516 FQCLCPPGF 524
Score = 134 bits (324), Expect = 1e-30
Identities = 127/442 (28%), Positives = 177/442 (40%), Gaps = 56/442 (12%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
GTC D F C C G+ T C +++ECS PC CV+ G + C CP
Sbjct: 1000 GTCVDGINSFSCLCPVGF----TGSFCLHEINECS--SHPCLNEGTCVDGLGTYRCSCPL 1053
Query: 140 GYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYRCECKPG----YTLRENVCRDVDE 194
GY + C+ V+ C + G C +C C G Y NV D+
Sbjct: 1054 GY----TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAA 1109
Query: 195 CSRP---RPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CR 249
R +C++ G C N + C C G+ + +D EC C++G C
Sbjct: 1110 SRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLD--ECASNP--CQHGATCS 1165
Query: 250 NTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
+ +G +RCEC PGY G NC +VDEC PC G +C + ++CSC G
Sbjct: 1166 DFIGGYRCECVPGY----QGVNCEYEVDECQN--QPCQNGG--TCIDLVNHFKCSCPPGT 1217
Query: 309 KLVGRRCVDR-DECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYD 367
+ G C + D+C P+ GG+C + GGY C C G+ ++ + C
Sbjct: 1218 R--GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSS 1275
Query: 368 EWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM-GRPNLTQD 426
E C +QL C A GR+CE D M GG + D
Sbjct: 1276 EGSLD-C-----IQLTNDYLCVCRSAFTGRHCETFV--DVCPQMPCLNGGTCAVASNMPD 1327
Query: 427 LDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV-----DADE-CALDPRICG 480
CR P G RC ++ G +C + V G C D + CA P G
Sbjct: 1328 GFICRCPPGFS-GARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHG 1386
Query: 481 NGTCSNTRGG--YECQCSPGFT 500
G+C R Y CQC+P F+
Sbjct: 1387 -GSCHPQRQPPYYSCQCAPPFS 1407
Score = 112 bits (269), Expect = 6e-24
Identities = 116/442 (26%), Positives = 159/442 (35%), Gaps = 58/442 (13%)
Query: 439 GGRCVNTD--GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSN-TRGGYECQC 495
GG CV G C C G+ + + C + GTC +R YEC C
Sbjct: 76 GGTCVAQAMLGKATCRCASGFT--GEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC 133
Query: 496 SPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDEC 554
GFT + C D C + C A F C C G+ G C D++EC
Sbjct: 134 QVGFT---GKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFT----GQKCETDVNEC 186
Query: 555 VQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCI 612
P C H C N+ GSY C+CP+G+ + C+ + +GG C
Sbjct: 187 -DIPGHCQHGGTCLNLPGSYQCQCPQGF--------TGQYCDSLYVPCAPSPCVNGGTCR 237
Query: 613 NT-DGSFLCDCDAGFEPS---EDGTDCIDRRT---GTCYRSL--VSGRCEPEXXXXXXXX 663
T D +F C+C GFE S + DC + R G C + + RC P+
Sbjct: 238 QTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTE 297
Query: 664 XXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSEC-ELCPAPGSPARLDLCTAVNLTPXXX 722
G C +G C +D C + TP
Sbjct: 298 DVDECLLQPNACQNGGT-----CANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGST 352
Query: 723 XXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP----GLCAP----GRFRCVCGPGYRPA 774
L D D C + P LC G++ C C GY+ A
Sbjct: 353 CIDRVASFSCMCPEGKAGLL-CHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGA 410
Query: 775 GEVCADVDECAV-RPPPCDQL--CHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTH 830
+ DVDECA+ PC+ C NTDG++ C C GY G C D++EC D
Sbjct: 411 -DCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDPC 465
Query: 831 TCQQICSNTEGSYECSCEDGYE 852
C + G + C C G++
Sbjct: 466 QNDATCLDKIGGFTCLCMPGFK 487
Score = 64.5 bits (150), Expect = 2e-09
Identities = 34/98 (34%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 820
+ C+C PG++ G+ C D+DEC +P LCHNT GSY C C G+ G +C
Sbjct: 857 YTCLCAPGWQ--GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGF----SGMDCEE 910
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
D+D+C + C + ++ C C G+ GD C
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGF--TGDKC 946
Score = 60.5 bits (140), Expect = 2e-08
Identities = 35/108 (32%), Positives = 51/108 (47%), Gaps = 12/108 (11%)
Query: 756 GLCAPG--RFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY 810
G+C G + C C P + G+ C DVDEC ++P C C N +G Y C+C G+
Sbjct: 273 GVCVDGVNTYNCRCPPQW--TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGW 330
Query: 811 ELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
D+ N +D+C + T C + S+ C C +G K G C
Sbjct: 331 SGDDCSEN---IDDCAFASCTPGSTCIDRVASFSCMCPEG--KAGLLC 373
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/118 (30%), Positives = 55/118 (46%), Gaps = 14/118 (11%)
Query: 742 LDVFADVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQL 794
+D D+D+C A P G C G F C+C PG+ G+ C D++EC P
Sbjct: 906 MDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGF--TGDKCQTDMNECLSEPCKNGGT 963
Query: 795 CHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C + SY C C+ G+ DG +C +++EC + C + S+ C C G+
Sbjct: 964 CSDYVNSYTCKCQAGF----DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGF 1017
Score = 52.4 bits (120), Expect = 7e-06
Identities = 36/107 (33%), Positives = 46/107 (42%), Gaps = 12/107 (11%)
Query: 756 GLC--APGRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G+C A C C GY G C + +DECA P C + G Y C C GY+
Sbjct: 1124 GVCINAGNTHYCQCPLGY--TGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQ- 1180
Query: 813 DEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
G NC +VDEC+ C + ++CSC G RG C
Sbjct: 1181 ---GVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG--TRGLLC 1222
Score = 52.0 bits (119), Expect = 9e-06
Identities = 69/272 (25%), Positives = 92/272 (33%), Gaps = 41/272 (15%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
ID+C P G C D G+ C C G+ + D++EC G C+
Sbjct: 1226 IDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE---GDINECLSNPCSSEGSLDCI 1282
Query: 128 NLPGAFECRCPPGYRLTPSLDECED-VDECGDQRICDHGDC---RNTIGSYRCECKPGYT 183
L + C C + + CE VD C + G C N + C C PG+
Sbjct: 1283 QLTNDYLCVCRSAF----TGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGF- 1337
Query: 184 LRENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMV 242
+ R C + + CR G C + C C + C + C+ GG
Sbjct: 1338 ---SGARCQSSCGQVK--CRKGEQCVHTASGPRCFCPS--PRDCESGCAS-SPCQHGGS- 1388
Query: 243 CRNGR--------CRNTVGSFRCE--CAPGYT--LTADGRNCRDVDE---CDEL--PHPC 285
C R C RCE AP T T + C D CDE H C
Sbjct: 1389 CHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHAC 1448
Query: 286 GRDGNP-SCTNTNGGYECSCGAG-WKLVGRRC 315
DG S T N CS W + +C
Sbjct: 1449 QWDGGDCSLTMENPWANCSSPLPCWDYINNQC 1480
Score = 42.7 bits (96), Expect = 0.005
Identities = 33/115 (28%), Positives = 53/115 (46%), Gaps = 18/115 (15%)
Query: 747 DVDECAAIP----GLCAP--GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTD 799
D++EC + P G C+ + C C G+ G C + ++EC C +
Sbjct: 949 DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD--GVHCENNINECTESSCFNGGTCVDGI 1006
Query: 800 GSYDCLCRTGYELDEDGANC-RDVDECERDTHTC--QQICSNTEGSYECSCEDGY 851
S+ CLC G+ G+ C +++EC +H C + C + G+Y CSC GY
Sbjct: 1007 NSFSCLCPVGFT----GSFCLHEINECS--SHPCLNEGTCVDGLGTYRCSCPLGY 1055
Score = 41.9 bits (94), Expect = 0.009
Identities = 35/122 (28%), Positives = 49/122 (40%), Gaps = 18/122 (14%)
Query: 747 DVDECAAIP----GLC--APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D +EC + P G C +RC C G++ G C ++DECA P C +
Sbjct: 757 DKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK--GYNCQVNIDECASNPCLNQGTCFDDI 814
Query: 800 GSYDCLCRTGYELDEDGANCRDV-DECERDTHTCQQICSNTEG--SYECSCEDGYEKRGD 856
Y C C Y G NC+ V C + +C + SY C C G++ G
Sbjct: 815 SGYTCHCVLPY----TGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ--GQ 868
Query: 857 AC 858
C
Sbjct: 869 RC 870
>AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
protein.
Length = 2471
Score = 258 bits (632), Expect = 6e-68
Identities = 238/820 (29%), Positives = 331/820 (40%), Gaps = 113/820 (13%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD-VDECSWGRPPCRGMAQC 126
ID+C P L C D P G++C C G+ T LC + +D C PC QC
Sbjct: 533 IDDCSSTPCL-NGAKCIDHPNGYECQCATGF----TGVLCEENIDNCD--PDPCHH-GQC 584
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
+ ++ C C PGY D+ +DEC + G C + + Y+C C+PG T
Sbjct: 585 QDGIDSYTCICNPGYMGAICSDQ---IDECYSSPCLNDGRCIDLVNGYQCNCQPG-TSGV 640
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
N + D+C+ P C +G C + Y C C GF N +D++EC CR G
Sbjct: 641 NCEINFDDCAS-NP-CIHGICMDGINRYSCVCSPGFTGQRCN--IDIDECASNP--CRKG 694
Query: 247 R-CRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
C N V FRC C G +C V+EC L +PC GN CT GY+C C
Sbjct: 695 ATCINGVNGFRCICPEG----PHHPSCYSQVNEC--LSNPCIH-GN--CTGGLSGYKCLC 745
Query: 305 GAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDE-- 360
AGW VG C VD++EC P C GG C N GY C C G++ V +DE
Sbjct: 746 DAGW--VGINCEVDKNECLSNP--CQNGGTCDNLVNGYRCTCKKGFK-GYNCQVNIDECA 800
Query: 361 -----RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP----APDSAEFM 411
+ C+D+ CH P C CE +P+ +
Sbjct: 801 SNPCLNQGTCFDDISGYTCHCVLPY--TGKNCQTVLAPCSPNPCENAAVCKESPNFESYT 858
Query: 412 RICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCV-DA 469
+C G T D+DEC +P C+ G C NT GS+ CECP G+ G+ C D
Sbjct: 859 CLCAPGWQGQRCTIDIDECISKP--CMNHGLCHNTQGSYMCECPPGF----SGMDCEEDI 912
Query: 470 DECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTA 528
D+C +P C NG +C + + C C PGFT QT D++EC C +
Sbjct: 913 DDCLANP--CQNGGSCMDGVNTFSCLCLPGFTGDKCQT--DMNECLSEPCKNGGTCSDYV 968
Query: 529 GSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQ 587
S+ C C G+ DGVHC + I+EC + C + + S+ C CP G+ +
Sbjct: 969 NSYTCKCQAGF----DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFC-- 1022
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGT--DCIDR----RTG 641
+INEC L + G C++ G++ C C G+ T + R G
Sbjct: 1023 -----LHEINECSSHPCL-NEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKG 1076
Query: 642 TCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQC-----CCTLGAAWGSE 696
TC + +C G + + C C G +
Sbjct: 1077 TCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQ 1136
Query: 697 CELCPAPGS--PARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAI 754
C L GS +LD C A N ++ +VDEC
Sbjct: 1137 CPL-GYTGSYCEEQLDEC-ASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQ 1194
Query: 755 P----GLCAP--GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPC--DQLCHNTDGSYDCL 805
P G C F+C C PG R G +C + +D+CA R P C C + G Y C
Sbjct: 1195 PCQNGGTCIDLVNHFKCSCPPGTR--GLLCEENIDDCA-RGPHCLNGGQCMDRIGGYSCR 1251
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC 845
C G+ + CE D + C ++EGS +C
Sbjct: 1252 CLPGFA----------GERCEGDINECLSNPCSSEGSLDC 1281
Score = 227 bits (556), Expect = 1e-58
Identities = 189/617 (30%), Positives = 272/617 (44%), Gaps = 94/617 (15%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQC 126
I+EC P + G C D FQC C G+ T +C+ D+D+CS PC A+C
Sbjct: 495 INECQSNPCV-NNGQCVDKVNRFQCLCPPGF----TGPVCQIDIDDCS--STPCLNGAKC 547
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
++ P +EC+C G+ T L E E++D C D C HG C++ I SY C C PGY
Sbjct: 548 IDHPNGYECQCATGF--TGVLCE-ENIDNC-DPDPCHHGQCQDGIDSYTCICNPGYM--G 601
Query: 187 NVCRD-VDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN 245
+C D +DEC P +G C +L Y C+C G +G N + ++ ++C C +
Sbjct: 602 AICSDQIDECYSS-PCLNDGRCIDLVNGYQCNCQPG-TSGVNCE-INFDDCASNP--CIH 656
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
G C + + + C C+PG+T G+ C D+DEC +PC R G +C N G+ C C
Sbjct: 657 GICMDGINRYSCVCSPGFT----GQRCNIDIDECAS--NPC-RKG-ATCINGVNGFRCIC 708
Query: 305 GAGWKLVGRRCVDR-DECKELPYVCAGGECRNFNGGYVCECPAGW-----RFDKTAAVCV 358
G C + +EC P C G C GY C C AGW DK +
Sbjct: 709 PEGPHHPS--CYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSN 764
Query: 359 D-ERKELCYDEWEAGRC-----HRARPLQLARPEC----CCSEGAAW---GRYCERCPAP 405
+ C + RC + Q+ EC C ++G + Y C P
Sbjct: 765 PCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLP 824
Query: 406 DSAEFMRICQGGMG--RPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDG 463
+ + CQ + PN ++ C+ P+ S+ C C G+ G
Sbjct: 825 YTG---KNCQTVLAPCSPNPCENAAVCKESPNF----------ESYTCLCAPGW----QG 867
Query: 464 LSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF 522
C +D DEC P + +G C NT+G Y C+C PGF+ G D D+D+C
Sbjct: 868 QRCTIDIDECISKPCM-NHGLCHNTQGSYMCECPPGFS-GMDCE-EDIDDCLANPCQNGG 924
Query: 523 RCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + +F C C G+ G C+ D++EC+ EP C + V SY CKC G+
Sbjct: 925 SCMDGVNTFSCLCLPGFT----GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF- 979
Query: 582 RTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPS---EDGTDCIDR 638
D + +INEC E +GG C++ SF C C GF S + +C
Sbjct: 980 ------DGVHCENNINECTE-SSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSH 1032
Query: 639 ---RTGTCYRSLVSGRC 652
GTC L + RC
Sbjct: 1033 PCLNEGTCVDGLGTYRC 1049
Score = 221 bits (541), Expect = 6e-57
Identities = 179/583 (30%), Positives = 246/583 (42%), Gaps = 72/583 (12%)
Query: 92 CGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLP-GAFECRCPPGYRLTPSLDEC 150
C C G+ ++ + C RP C C L +EC C G+ + EC
Sbjct: 90 CRCASGFTGEDCQYSTSH--PCFVSRP-CLNGGTCHMLSRDTYECTCQVGF----TGKEC 142
Query: 151 EDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGTCEN 209
+ D C + C + C+C G+T ++ C DV+EC P GTC N
Sbjct: 143 QWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQK--CETDVNECDIPGHCQHGGTCLN 200
Query: 210 LPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVG-SFRCECAPGYTLTAD 268
LPG+Y C C GF G D + V C V G CR T +F C C PG+ +
Sbjct: 201 LPGSYQCQCPQGF-TGQYCDSLYV-PCAPSPCV-NGGTCRQTGDFTFECNCLPGF----E 253
Query: 269 GRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV-DRDECKELPY 326
G C R++D+C H C G C + Y C C W G+ C D DEC P
Sbjct: 254 GSTCERNIDDCPN--HRCQNGG--VCVDGVNTYNCRCPPQW--TGQFCTEDVDECLLQPN 307
Query: 327 VCA-GGECRNFNGGYVCECPAGWRFDKTA------AVCVDERKELCYDEWEAGRC---HR 376
C GG C N NGGY C C GW D + A C D + C
Sbjct: 308 ACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEG 367
Query: 377 ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRV-RPD 435
L + C S G C+ P + +++ C G + T+D+DEC + +
Sbjct: 368 KAGLLCHLDDACISNPCHKGALCDTNPL--NGQYICTCPQGYKGADCTEDVDECAMANSN 425
Query: 436 VCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGN-GTCSNTRGGYE 492
C G+CVNTDG+F CEC GY G C +D +EC DP C N TC + GG+
Sbjct: 426 PCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDP--CQNDATCLDKIGGFT 479
Query: 493 CQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DI 551
C C PGF +G ++++EC +C + F+C CP G+ G C+ DI
Sbjct: 480 CLCMPGF-KGV-HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFT----GPVCQIDI 533
Query: 552 DECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVC 611
D+C P + C + Y C+C G+ E+I+ C+ D C G C
Sbjct: 534 DDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCE-------ENIDNCD--PDPCHHGQC 584
Query: 612 INTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS--LVSGRC 652
+ S+ C C+ G+ G C D + CY S L GRC
Sbjct: 585 QDGIDSYTCICNPGYM----GAICSD-QIDECYSSPCLNDGRC 622
Score = 221 bits (539), Expect = 1e-56
Identities = 201/672 (29%), Positives = 286/672 (42%), Gaps = 96/672 (14%)
Query: 21 YLCCCSVGHAWGAPC---EACPPRGSPAHT-ALCGEKP--GEYINPVTNE------TKPI 68
+ C C G A G C +AC +P H ALC P G+YI T+ +
Sbjct: 360 FSCMCPEGKA-GLLCHLDDACI--SNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDV 416
Query: 69 DECDIM-PQLCK-PGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
DEC + C+ G C +T F C C GY D++EC PC+ A C
Sbjct: 417 DECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE---MDINECH--SDPCQNDATC 471
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
++ G F C C PG++ CE +++EC ++G C + + ++C C PG+T
Sbjct: 472 LDKIGGFTCLCMPGFKGV----HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFT-- 525
Query: 186 ENVCR-DVDECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC 243
VC+ D+D+CS C NG C + P Y C C GF + +D C C
Sbjct: 526 GPVCQIDIDDCSSTP--CLNGAKCIDHPNGYECQCATGFTGVLCEENID--NCDPDP--C 579
Query: 244 RNGRCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGGYEC 302
+G+C++ + S+ C C PGY G C D +DEC PC DG C + GY+C
Sbjct: 580 HHGQCQDGIDSYTCICNPGYM----GAICSDQIDEC--YSSPCLNDGR--CIDLVNGYQC 631
Query: 303 SCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE- 360
+C G G C ++ D+C P C G C + Y C C G+ + + +DE
Sbjct: 632 NCQPGTS--GVNCEINFDDCASNP--CIHGICMDGINRYSCVCSPGFTGQR-CNIDIDEC 686
Query: 361 -----RK-ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYC--ERCPAPDSAEFMR 412
RK C + RC P P C C C S +
Sbjct: 687 ASNPCRKGATCINGVNGFRC--ICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSG-YKC 743
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDAD 470
+C G N D +EC P C GG C N +RC C G+ G +C V+ D
Sbjct: 744 LCDAGWVGINCEVDKNECLSNP--CQNGGTCDNLVNGYRCTCKKGF----KGYNCQVNID 797
Query: 471 ECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAG- 529
ECA +P + GTC + GY C C +T QT + C+ C +
Sbjct: 798 ECASNPCL-NQGTCFDDISGYTCHCVLPYTGKNCQTVLA--PCSPNPCENAAVCKESPNF 854
Query: 530 -SFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQ 587
S+ C C G+ G C DIDEC+ +P + C N GSY+C+CP G+ +
Sbjct: 855 ESYTCLCAPGW----QGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGF----SGM 906
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTD---CID---RRTG 641
D E EDI++C +GG C++ +F C C GF + TD C+ + G
Sbjct: 907 DCE---EDIDDC-LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGG 962
Query: 642 TCYRSLVSGRCE 653
TC + S C+
Sbjct: 963 TCSDYVNSYTCK 974
Score = 220 bits (538), Expect = 1e-56
Identities = 241/888 (27%), Positives = 341/888 (38%), Gaps = 127/888 (14%)
Query: 20 KYLCCCSVGHAWGAPCEA----CPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMP 75
++ C C G G CE C G H C PG Y CD +
Sbjct: 165 QFSCKCLTGFT-GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTG-QYCDSLY 222
Query: 76 QLCKP------GTCHDTPT-GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
C P GTC T F+C C G+E R++D+C R C+ CV+
Sbjct: 223 VPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCE---RNIDDCPNHR--CQNGGVCVD 277
Query: 129 LPGAFECRCPPGYRLTPSLDEC-EDVDECGDQ-RICDHGD-CRNTIGSYRCECKPGYTLR 185
+ CRCPP + + C EDVDEC Q C +G C N G Y C C G++
Sbjct: 278 GVNTYNCRCPPQW----TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWS-G 332
Query: 186 ENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGP----NNDCVDVNECREGG 240
++ ++D+C+ C G TC + ++ C C +G KAG ++ C+ N C +G
Sbjct: 333 DDCSENIDDCAFAS--CTPGSTCIDRVASFSCMCPEG-KAGLLCHLDDACIS-NPCHKGA 388
Query: 241 MVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDEL-PHPCGRDGNPSCTNTNG 298
+ N G + C C GY G +C DVDEC +PC G C NT+G
Sbjct: 389 LCDTNP----LNGQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGK--CVNTDG 438
Query: 299 GYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRFDKTAAV 356
+ C C G+ G RC +D +EC P C C + GG+ C C G++
Sbjct: 439 AFHCECLKGY--AGPRCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFKGVHCELE 494
Query: 357 CVDERKELCYDEWEA----GRCHRARPLQLARPEC------CCSEGAAWGRYCERCPAPD 406
+ + C + + R P P C C S G C P+
Sbjct: 495 INECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKC--IDHPN 552
Query: 407 SAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
E C G +++D C PD C G+C + S+ C C GY+ G C
Sbjct: 553 GYECQ--CATGFTGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYM----GAIC 604
Query: 467 VDA-DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
D DEC P + +G C + GY+C C PG T G + ++ D+CA C
Sbjct: 605 SDQIDECYSSPCL-NDGRCIDLVNGYQCNCQPG-TSGVNCE-INFDDCASNPCIHGI-CM 660
Query: 526 NTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
+ + C C G+ G C DIDEC P C N V + C CPEG S
Sbjct: 661 DGINRYSCVCSPGFT----GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPS 716
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF---EPSEDGTDCID---R 638
+NEC C G C + C CDAG+ D +C+ +
Sbjct: 717 C-------YSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQ 767
Query: 639 RTGTCYRSLVSG-RCEPEXXXXXXXXXXXXXXXXXX-----XXXXGHVTKAQCCCTLGAA 692
GTC +LV+G RC + ++ C C L
Sbjct: 768 NGGTC-DNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYT 826
Query: 693 WGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECA 752
G C+ AP SP + +P D+DEC
Sbjct: 827 -GKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTI-------DIDECI 878
Query: 753 AIP----GLC--APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCL 805
+ P GLC G + C C PG+ +G C D+D+C P C + ++ CL
Sbjct: 879 SKPCMNHGLCHNTQGSYMCECPPGF--SGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCL 936
Query: 806 CRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
C G+ G C+ D++EC + CS+ SY C C+ G++
Sbjct: 937 CLPGFT----GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD 980
Score = 205 bits (501), Expect = 5e-52
Identities = 177/575 (30%), Positives = 257/575 (44%), Gaps = 90/575 (15%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDV-DECSWGRPPCRGMAQC 126
IDEC P L GTC D +G+ C C Y N C+ V CS PC A C
Sbjct: 796 IDECASNPCL-NQGTCFDDISGYTCHCVLPYTGKN----CQTVLAPCSPN--PCENAAVC 848
Query: 127 VNLPG--AFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYT 183
P ++ C C PG++ C D+DEC + +HG C NT GSY CEC PG++
Sbjct: 849 KESPNFESYTCLCAPGWQG----QRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFS 904
Query: 184 LRENVC-RDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGM 241
+ C D+D+C P G+C + + C C GF + C D+NEC
Sbjct: 905 GMD--CEEDIDDC-LANPCQNGGSCMDGVNTFSCLCLPGF---TGDKCQTDMNECL--SE 956
Query: 242 VCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGG 299
C+N G C + V S+ C+C G+ DG +C +++EC E C G +C +
Sbjct: 957 PCKNGGTCSDYVNSYTCKCQAGF----DGVHCENNINECTE--SSCFNGG--TCVDGINS 1008
Query: 300 YECSCGAGWKLVGRRCV-DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV 358
+ C C G+ G C+ + +EC P + G C + G Y C CP G+ +
Sbjct: 1009 FSCLCPVGF--TGSFCLHEINECSSHPCL-NEGTCVDGLGTYRCSCPLGYTGKNCQTLVN 1065
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
+ C ++ G C + + A +C C G A G YC+ P+ + + + G+
Sbjct: 1066 LCSRSPCKNK---GTCVQKK----AESQCLCPSGWA-GAYCD---VPNVSCDIAASRRGV 1114
Query: 419 GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD-ADECALDPR 477
+L Q G C+N + C+CP GY G C + DECA +P
Sbjct: 1115 LVEHLCQH------------SGVCINAGNTHYCQCPLGYT----GSYCEEQLDECASNP- 1157
Query: 478 ICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCP 536
C +G TCS+ GGY C+C PG+ QG + +VDEC C + F+C+CP
Sbjct: 1158 -CQHGATCSDFIGGYRCECVPGY-QGVNCE-YEVDECQNQPCQNGGTCIDLVNHFKCSCP 1214
Query: 537 YGYAVAADGVHCRD-IDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENAC 593
G G+ C + ID+C + P C + C + +G Y C+C G+ + C
Sbjct: 1215 PG----TRGLLCEENIDDCARGPH-CLNGGQCMDRIGGYSCRCLPGF--------AGERC 1261
Query: 594 E-DINECEEQEDLCSGGV-CINTDGSFLCDCDAGF 626
E DINEC G + CI +LC C + F
Sbjct: 1262 EGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF 1296
Score = 198 bits (482), Expect = 9e-50
Identities = 184/673 (27%), Positives = 265/673 (39%), Gaps = 99/673 (14%)
Query: 21 YLCCCSVGHA-----WGAPCEACPPRGSPAHTALCGEKPGEYINPVTNET--KPIDECDI 73
Y C C VG W C + P T + + + + T + ++ECDI
Sbjct: 129 YECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 188
Query: 74 MPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG-A 132
GTC + P +QC C G+ T C D PC C
Sbjct: 189 PGHCQHGGTCLNLPGSYQCQCPQGF----TGQYC-DSLYVPCAPSPCVNGGTCRQTGDFT 243
Query: 133 FECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRD 191
FEC C PG+ + CE ++D+C + R + G C + + +Y C C P +T + D
Sbjct: 244 FECNCLPGFEGS----TCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWT-GQFCTED 298
Query: 192 VDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVD-VNECREGGMVCRNG-RC 248
VDEC C+N GTC N G Y C C +G+ +DC + +++C C G C
Sbjct: 299 VDECLLQPNACQNGGTCANRNGGYGCVCVNGWS---GDDCSENIDDCAFAS--CTPGSTC 353
Query: 249 RNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
+ V SF C C G G C D C + +PC + NG Y C+C G+
Sbjct: 354 IDRVASFSCMCPEGKA----GLLCHLDDAC--ISNPCHKGALCDTNPLNGQYICTCPQGY 407
Query: 309 KLVGRRCV-DRDECKEL-PYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
K G C D DEC C G+C N +G + CEC G+ R E+
Sbjct: 408 K--GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY---------AGPRCEMD 456
Query: 366 YDEWEAGRCHRARPL--QLARPECCCSEGAAWGRYCE----RC---PAPDSAE------- 409
+E + C ++ C C G G +CE C P ++ +
Sbjct: 457 INECHSDPCQNDATCLDKIGGFTCLCMPGFK-GVHCELEINECQSNPCVNNGQCVDKVNR 515
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
F +C G P D+D+C P C+ G +C++ + C+C G+ G+ C +
Sbjct: 516 FQCLCPPGFTGPVCQIDIDDCSSTP--CLNGAKCIDHPNGYECQCATGFT----GVLCEE 569
Query: 469 -ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHN 526
D C DP C +G C + Y C C+PG+ C D +DEC RC +
Sbjct: 570 NIDNC--DPDPCHHGQCQDGIDSYTCICNPGYM---GAICSDQIDECYSSPCLNDGRCID 624
Query: 527 TAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTS 584
++C C G GV+C + D+C P C H C + + Y C C G+
Sbjct: 625 LVNGYQCNCQPG----TSGVNCEINFDDCASNP--CIHGICMDGINRYSCVCSPGF---- 674
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG-FEPS--EDGTDCIDRRT- 640
+ DI+EC G CIN F C C G PS +C+
Sbjct: 675 ---TGQRCNIDIDEC-ASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCI 730
Query: 641 -GTCYRSLVSGRC 652
G C L +C
Sbjct: 731 HGNCTGGLSGYKC 743
Score = 196 bits (477), Expect = 4e-49
Identities = 172/616 (27%), Positives = 254/616 (41%), Gaps = 102/616 (16%)
Query: 75 PQLCK-PGTCHDTPT--GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG 131
P C+ C ++P + C C G++ + D+DEC PC C N G
Sbjct: 839 PNPCENAAVCKESPNFESYTCLCAPGWQGQRCTI---DIDECI--SKPCMNHGLCHNTQG 893
Query: 132 AFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRD 191
++ C CPPG+ +D ED+D+C + G C + + ++ C C PG+T + D
Sbjct: 894 SYMCECPPGFS---GMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFT-GDKCQTD 949
Query: 192 VDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RC 248
++EC S P C+NG TC + +Y C C GF + ++NEC E C NG C
Sbjct: 950 MNECLSEP---CKNGGTCSDYVNSYTCKCQAGFDGVHCEN--NINECTESS--CFNGGTC 1002
Query: 249 RNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
+ + SF C C G+T G C +++EC HPC +G +C + G Y CSC G
Sbjct: 1003 VDGINSFSCLCPVGFT----GSFCLHEINECSS--HPCLNEG--TCVDGLGTYRCSCPLG 1054
Query: 308 WKLVGRRCVDR-DECKELPYVCAG-GECRNFNGGYVCECPAGWRF------DKTAAVCVD 359
+ G+ C + C P C G C C CP+GW + + +
Sbjct: 1055 Y--TGKNCQTLVNLCSRSP--CKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAAS 1110
Query: 360 ER----KELCYDEW---EAGRCHRAR-PLQLARPEC------CCSEGAAWGRYCERCPAP 405
R + LC AG H + PL C C S G C
Sbjct: 1111 RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGG 1170
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGL 464
E C G N ++DEC+ +P C GG C++ F+C CP G GL
Sbjct: 1171 YRCE----CVPGYQGVNCEYEVDECQNQP--CQNGGTCIDLVNHFKCSCPPG----TRGL 1220
Query: 465 SCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRASC-- 520
C + D+CA P G C + GGY C+C PGF + C D++EC S
Sbjct: 1221 LCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA---GERCEGDINECLSNPCSSEG 1277
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPHAC---ENVVGSYICKC 576
+ C + C C + G HC +D C Q P + C N+ +IC+C
Sbjct: 1278 SLDCIQLTNDYLCVCRSAFT----GRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRC 1333
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC------DCDAG--FEP 628
P G+ +++C + +C + E C++T C DC++G P
Sbjct: 1334 PPGFSGARC----QSSCGQV-KCRKGEQ------CVHTASGPRCFCPSPRDCESGCASSP 1382
Query: 629 SEDGTDCIDRRTGTCY 644
+ G C +R Y
Sbjct: 1383 CQHGGSCHPQRQPPYY 1398
Score = 182 bits (442), Expect = 6e-45
Identities = 193/682 (28%), Positives = 275/682 (40%), Gaps = 101/682 (14%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCE--ACPPRGSPAHTALCGEKPGEYINPVTNETKP 67
C A G T LC ++ + PC C G ++T +C PG Y+ + ++
Sbjct: 556 CQCATGF--TGVLCEENIDNCDPDPCHHGQCQD-GIDSYTCICN--PG-YMGAICSDQ-- 607
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P L G C D G+QC C G N + D+C+ P G+ C+
Sbjct: 608 IDECYSSPCL-NDGRCIDLVNGYQCNCQPGTSGVNCEI---NFDDCA-SNPCIHGI--CM 660
Query: 128 NLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
+ + C C PG+ + C D+DEC C N + +RC C G
Sbjct: 661 DGINRYSCVCSPGF----TGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG-PHHP 715
Query: 187 NVCRDVDEC-SRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN 245
+ V+EC S P C +G C Y C CD G+ G N + VD NEC C+N
Sbjct: 716 SCYSQVNECLSNP---CIHGNCTGGLSGYKCLCDAGW-VGINCE-VDKNECLSNP--CQN 768
Query: 246 G-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECS 303
G C N V +RC C G+ G NC+ ++DEC +PC G +C + GY C
Sbjct: 769 GGTCDNLVNGYRCTCKKGFK----GYNCQVNIDECAS--NPCLNQG--TCFDDISGYTCH 820
Query: 304 CGAGWKLVGRRCVD-RDECKELPYVCAG--GECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
C + G+ C C P A E NF Y C C GW+ + + +DE
Sbjct: 821 CVLPY--TGKNCQTVLAPCSPNPCENAAVCKESPNFES-YTCLCAPGWQGQR-CTIDIDE 876
Query: 361 R-KELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCER----C---PAPDSAE--- 409
+ C + G CH + + C C G + G CE C P +
Sbjct: 877 CISKPCMNH---GLCHNTQGSYM----CECPPGFS-GMDCEEDIDDCLANPCQNGGSCMD 928
Query: 410 ----FMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGL 464
F +C G D++EC P C GG C + S+ C+C G+ DG+
Sbjct: 929 GVNTFSCLCLPGFTGDKCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGF----DGV 982
Query: 465 SCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRASCTF 522
C + +EC + GTC + + C C GFT C+ +++EC+
Sbjct: 983 HCENNINECT-ESSCFNGGTCVDGINSFSCLCPVGFT---GSFCLHEINECSSHPCLNEG 1038
Query: 523 RCHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + G++RC+CP GY G +C+ ++ C + P C C CP G+
Sbjct: 1039 TCVDGLGTYRCSCPLGYT----GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW- 1093
Query: 582 RTSAPQDSENACEDINECEEQ---EDLCS-GGVCINTDGSFLCDCDAGFEPS---EDGTD 634
A D N DI E LC GVCIN + C C G+ S E +
Sbjct: 1094 -AGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDE 1152
Query: 635 CID---RRTGTCYRSLVSGRCE 653
C + TC + RCE
Sbjct: 1153 CASNPCQHGATCSDFIGGYRCE 1174
Score = 177 bits (430), Expect = 2e-43
Identities = 159/549 (28%), Positives = 217/549 (39%), Gaps = 85/549 (15%)
Query: 112 ECSWGRPPCRGMAQCVNLP-GAFECRCPPGYRLTPSLDE-CEDVDECGDQRICDHGDC-- 167
+C G PC CV G C+CP G+ L E C+ D C R + G C
Sbjct: 27 QCRDGYEPCVNEGMCVTYHNGTGYCKCPEGF-----LGEYCQHRDPCEKNRCQNGGTCVA 81
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLP-GAYLCHCDDGFKAGP 226
+ +G C C G+T + C RP GTC L Y C C GF
Sbjct: 82 QAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGF---T 138
Query: 227 NNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHP 284
+C + C C NG C F C+C G+T G+ C DV+ECD +P
Sbjct: 139 GKECQWTDACL--SHPCANGSTCTTVANQFSCKCLTGFT----GQKCETDVNECD-IPGH 191
Query: 285 CGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNG-GYVC 342
C G +C N G Y+C C G+ G+ C D P C GG CR + C
Sbjct: 192 CQHGG--TCLNLPGSYQCQCPQGF--TGQYC-DSLYVPCAPSPCVNGGTCRQTGDFTFEC 246
Query: 343 ECPAGWRFD--------------KTAAVCVDERKEL---CYDEWEAGRCHRARPLQLARP 385
C G+ + VCVD C +W C L +P
Sbjct: 247 NCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP 306
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNT 445
C + G R + + +C G + ++++D+C G C++
Sbjct: 307 NACQNGGTCANR---------NGGYGCVCVNGWSGDDCSENIDDCAF-ASCTPGSTCIDR 356
Query: 446 DGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNT---RGGYECQCSPGFTQG 502
SF C CP+G GL C D C +P C G +T G Y C C G+ +G
Sbjct: 357 VASFSCMCPEGKA----GLLCHLDDACISNP--CHKGALCDTNPLNGQYICTCPQGY-KG 409
Query: 503 PDQTCVDVDECAEGRAS-CTF--RCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEP 558
D T DVDECA ++ C +C NT G+F C C GYA G C DI+EC +P
Sbjct: 410 ADCT-EDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDP 464
Query: 559 RVCPHACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGS 617
C + +G + C C G++ CE +INEC + + G C++
Sbjct: 465 CQNDATCLDKIGGFTCLCMPGFKGVH--------CELEINEC-QSNPCVNNGQCVDKVNR 515
Query: 618 FLCDCDAGF 626
F C C GF
Sbjct: 516 FQCLCPPGF 524
Score = 134 bits (324), Expect = 1e-30
Identities = 127/442 (28%), Positives = 177/442 (40%), Gaps = 56/442 (12%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
GTC D F C C G+ T C +++ECS PC CV+ G + C CP
Sbjct: 1000 GTCVDGINSFSCLCPVGF----TGSFCLHEINECS--SHPCLNEGTCVDGLGTYRCSCPL 1053
Query: 140 GYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYRCECKPG----YTLRENVCRDVDE 194
GY + C+ V+ C + G C +C C G Y NV D+
Sbjct: 1054 GY----TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAA 1109
Query: 195 CSRP---RPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CR 249
R +C++ G C N + C C G+ + +D EC C++G C
Sbjct: 1110 SRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLD--ECASNP--CQHGATCS 1165
Query: 250 NTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
+ +G +RCEC PGY G NC +VDEC PC G +C + ++CSC G
Sbjct: 1166 DFIGGYRCECVPGY----QGVNCEYEVDECQN--QPCQNGG--TCIDLVNHFKCSCPPGT 1217
Query: 309 KLVGRRCVDR-DECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYD 367
+ G C + D+C P+ GG+C + GGY C C G+ ++ + C
Sbjct: 1218 R--GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSS 1275
Query: 368 EWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM-GRPNLTQD 426
E C +QL C A GR+CE D M GG + D
Sbjct: 1276 EGSLD-C-----IQLTNDYLCVCRSAFTGRHCETFV--DVCPQMPCLNGGTCAVASNMPD 1327
Query: 427 LDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV-----DADE-CALDPRICG 480
CR P G RC ++ G +C + V G C D + CA P G
Sbjct: 1328 GFICRCPPGFS-GARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHG 1386
Query: 481 NGTCSNTRGG--YECQCSPGFT 500
G+C R Y CQC+P F+
Sbjct: 1387 -GSCHPQRQPPYYSCQCAPPFS 1407
Score = 112 bits (269), Expect = 6e-24
Identities = 116/442 (26%), Positives = 159/442 (35%), Gaps = 58/442 (13%)
Query: 439 GGRCVNTD--GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSN-TRGGYECQC 495
GG CV G C C G+ + + C + GTC +R YEC C
Sbjct: 76 GGTCVAQAMLGKATCRCASGFT--GEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC 133
Query: 496 SPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDEC 554
GFT + C D C + C A F C C G+ G C D++EC
Sbjct: 134 QVGFT---GKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFT----GQKCETDVNEC 186
Query: 555 VQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCI 612
P C H C N+ GSY C+CP+G+ + C+ + +GG C
Sbjct: 187 -DIPGHCQHGGTCLNLPGSYQCQCPQGF--------TGQYCDSLYVPCAPSPCVNGGTCR 237
Query: 613 NT-DGSFLCDCDAGFEPS---EDGTDCIDRRT---GTCYRSL--VSGRCEPEXXXXXXXX 663
T D +F C+C GFE S + DC + R G C + + RC P+
Sbjct: 238 QTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTE 297
Query: 664 XXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSEC-ELCPAPGSPARLDLCTAVNLTPXXX 722
G C +G C +D C + TP
Sbjct: 298 DVDECLLQPNACQNGGT-----CANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGST 352
Query: 723 XXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP----GLCAP----GRFRCVCGPGYRPA 774
L D D C + P LC G++ C C GY+ A
Sbjct: 353 CIDRVASFSCMCPEGKAGLL-CHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGA 410
Query: 775 GEVCADVDECAV-RPPPCDQL--CHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTH 830
+ DVDECA+ PC+ C NTDG++ C C GY G C D++EC D
Sbjct: 411 -DCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDPC 465
Query: 831 TCQQICSNTEGSYECSCEDGYE 852
C + G + C C G++
Sbjct: 466 QNDATCLDKIGGFTCLCMPGFK 487
Score = 64.5 bits (150), Expect = 2e-09
Identities = 34/98 (34%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 820
+ C+C PG++ G+ C D+DEC +P LCHNT GSY C C G+ G +C
Sbjct: 857 YTCLCAPGWQ--GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGF----SGMDCEE 910
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
D+D+C + C + ++ C C G+ GD C
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGF--TGDKC 946
Score = 60.5 bits (140), Expect = 2e-08
Identities = 35/108 (32%), Positives = 51/108 (47%), Gaps = 12/108 (11%)
Query: 756 GLCAPG--RFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY 810
G+C G + C C P + G+ C DVDEC ++P C C N +G Y C+C G+
Sbjct: 273 GVCVDGVNTYNCRCPPQW--TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGW 330
Query: 811 ELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
D+ N +D+C + T C + S+ C C +G K G C
Sbjct: 331 SGDDCSEN---IDDCAFASCTPGSTCIDRVASFSCMCPEG--KAGLLC 373
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/118 (30%), Positives = 55/118 (46%), Gaps = 14/118 (11%)
Query: 742 LDVFADVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQL 794
+D D+D+C A P G C G F C+C PG+ G+ C D++EC P
Sbjct: 906 MDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGF--TGDKCQTDMNECLSEPCKNGGT 963
Query: 795 CHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C + SY C C+ G+ DG +C +++EC + C + S+ C C G+
Sbjct: 964 CSDYVNSYTCKCQAGF----DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGF 1017
Score = 52.4 bits (120), Expect = 7e-06
Identities = 36/107 (33%), Positives = 46/107 (42%), Gaps = 12/107 (11%)
Query: 756 GLC--APGRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G+C A C C GY G C + +DECA P C + G Y C C GY+
Sbjct: 1124 GVCINAGNTHYCQCPLGY--TGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQ- 1180
Query: 813 DEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
G NC +VDEC+ C + ++CSC G RG C
Sbjct: 1181 ---GVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG--TRGLLC 1222
Score = 52.0 bits (119), Expect = 9e-06
Identities = 69/272 (25%), Positives = 92/272 (33%), Gaps = 41/272 (15%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
ID+C P G C D G+ C C G+ + D++EC G C+
Sbjct: 1226 IDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE---GDINECLSNPCSSEGSLDCI 1282
Query: 128 NLPGAFECRCPPGYRLTPSLDECED-VDECGDQRICDHGDC---RNTIGSYRCECKPGYT 183
L + C C + + CE VD C + G C N + C C PG+
Sbjct: 1283 QLTNDYLCVCRSAF----TGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGF- 1337
Query: 184 LRENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMV 242
+ R C + + CR G C + C C + C + C+ GG
Sbjct: 1338 ---SGARCQSSCGQVK--CRKGEQCVHTASGPRCFCPS--PRDCESGCAS-SPCQHGGS- 1388
Query: 243 CRNGR--------CRNTVGSFRCE--CAPGYT--LTADGRNCRDVDE---CDEL--PHPC 285
C R C RCE AP T T + C D CDE H C
Sbjct: 1389 CHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHAC 1448
Query: 286 GRDGNP-SCTNTNGGYECSCGAG-WKLVGRRC 315
DG S T N CS W + +C
Sbjct: 1449 QWDGGDCSLTMENPWANCSSPLPCWDYINNQC 1480
Score = 42.7 bits (96), Expect = 0.005
Identities = 33/115 (28%), Positives = 53/115 (46%), Gaps = 18/115 (15%)
Query: 747 DVDECAAIP----GLCAP--GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTD 799
D++EC + P G C+ + C C G+ G C + ++EC C +
Sbjct: 949 DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD--GVHCENNINECTESSCFNGGTCVDGI 1006
Query: 800 GSYDCLCRTGYELDEDGANC-RDVDECERDTHTC--QQICSNTEGSYECSCEDGY 851
S+ CLC G+ G+ C +++EC +H C + C + G+Y CSC GY
Sbjct: 1007 NSFSCLCPVGFT----GSFCLHEINECS--SHPCLNEGTCVDGLGTYRCSCPLGY 1055
Score = 41.9 bits (94), Expect = 0.009
Identities = 35/122 (28%), Positives = 49/122 (40%), Gaps = 18/122 (14%)
Query: 747 DVDECAAIP----GLC--APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D +EC + P G C +RC C G++ G C ++DECA P C +
Sbjct: 757 DKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK--GYNCQVNIDECASNPCLNQGTCFDDI 814
Query: 800 GSYDCLCRTGYELDEDGANCRDV-DECERDTHTCQQICSNTEG--SYECSCEDGYEKRGD 856
Y C C Y G NC+ V C + +C + SY C C G++ G
Sbjct: 815 SGYTCHCVLPY----TGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ--GQ 868
Query: 857 AC 858
C
Sbjct: 869 RC 870
>AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein.
Length = 2471
Score = 258 bits (632), Expect = 6e-68
Identities = 238/820 (29%), Positives = 331/820 (40%), Gaps = 113/820 (13%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD-VDECSWGRPPCRGMAQC 126
ID+C P L C D P G++C C G+ T LC + +D C PC QC
Sbjct: 533 IDDCSSTPCL-NGAKCIDHPNGYECQCATGF----TGVLCEENIDNCD--PDPCHH-GQC 584
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
+ ++ C C PGY D+ +DEC + G C + + Y+C C+PG T
Sbjct: 585 QDGIDSYTCICNPGYMGAICSDQ---IDECYSSPCLNDGRCIDLVNGYQCNCQPG-TSGV 640
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
N + D+C+ P C +G C + Y C C GF N +D++EC CR G
Sbjct: 641 NCEINFDDCAS-NP-CIHGICMDGINRYSCVCSPGFTGQRCN--IDIDECASNP--CRKG 694
Query: 247 R-CRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
C N V FRC C G +C V+EC L +PC GN CT GY+C C
Sbjct: 695 ATCINGVNGFRCICPEG----PHHPSCYSQVNEC--LSNPCIH-GN--CTGGLSGYKCLC 745
Query: 305 GAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDE-- 360
AGW VG C VD++EC P C GG C N GY C C G++ V +DE
Sbjct: 746 DAGW--VGINCEVDKNECLSNP--CQNGGTCDNLVNGYRCTCKKGFK-GYNCQVNIDECA 800
Query: 361 -----RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP----APDSAEFM 411
+ C+D+ CH P C CE +P+ +
Sbjct: 801 SNPCLNQGTCFDDISGYTCHCVLPY--TGKNCQTVLAPCSPNPCENAAVCKESPNFESYT 858
Query: 412 RICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCV-DA 469
+C G T D+DEC +P C+ G C NT GS+ CECP G+ G+ C D
Sbjct: 859 CLCAPGWQGQRCTIDIDECISKP--CMNHGLCHNTQGSYMCECPPGF----SGMDCEEDI 912
Query: 470 DECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTA 528
D+C +P C NG +C + + C C PGFT QT D++EC C +
Sbjct: 913 DDCLANP--CQNGGSCMDGVNTFSCLCLPGFTGDKCQT--DMNECLSEPCKNGGTCSDYV 968
Query: 529 GSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQ 587
S+ C C G+ DGVHC + I+EC + C + + S+ C CP G+ +
Sbjct: 969 NSYTCKCQAGF----DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFC-- 1022
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGT--DCIDR----RTG 641
+INEC L + G C++ G++ C C G+ T + R G
Sbjct: 1023 -----LHEINECSSHPCL-NEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKG 1076
Query: 642 TCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQC-----CCTLGAAWGSE 696
TC + +C G + + C C G +
Sbjct: 1077 TCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQ 1136
Query: 697 CELCPAPGS--PARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAI 754
C L GS +LD C A N ++ +VDEC
Sbjct: 1137 CPL-GYTGSYCEEQLDEC-ASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQ 1194
Query: 755 P----GLCAP--GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPC--DQLCHNTDGSYDCL 805
P G C F+C C PG R G +C + +D+CA R P C C + G Y C
Sbjct: 1195 PCQNGGTCIDLVNHFKCSCPPGTR--GLLCEENIDDCA-RGPHCLNGGQCMDRIGGYSCR 1251
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC 845
C G+ + CE D + C ++EGS +C
Sbjct: 1252 CLPGFA----------GERCEGDINECLSNPCSSEGSLDC 1281
Score = 227 bits (556), Expect = 1e-58
Identities = 189/617 (30%), Positives = 272/617 (44%), Gaps = 94/617 (15%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQC 126
I+EC P + G C D FQC C G+ T +C+ D+D+CS PC A+C
Sbjct: 495 INECQSNPCV-NNGQCVDKVNRFQCLCPPGF----TGPVCQIDIDDCS--STPCLNGAKC 547
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
++ P +EC+C G+ T L E E++D C D C HG C++ I SY C C PGY
Sbjct: 548 IDHPNGYECQCATGF--TGVLCE-ENIDNC-DPDPCHHGQCQDGIDSYTCICNPGYM--G 601
Query: 187 NVCRD-VDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN 245
+C D +DEC P +G C +L Y C+C G +G N + ++ ++C C +
Sbjct: 602 AICSDQIDECYSS-PCLNDGRCIDLVNGYQCNCQPG-TSGVNCE-INFDDCASNP--CIH 656
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
G C + + + C C+PG+T G+ C D+DEC +PC R G +C N G+ C C
Sbjct: 657 GICMDGINRYSCVCSPGFT----GQRCNIDIDECAS--NPC-RKG-ATCINGVNGFRCIC 708
Query: 305 GAGWKLVGRRCVDR-DECKELPYVCAGGECRNFNGGYVCECPAGW-----RFDKTAAVCV 358
G C + +EC P C G C GY C C AGW DK +
Sbjct: 709 PEGPHHPS--CYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSN 764
Query: 359 D-ERKELCYDEWEAGRC-----HRARPLQLARPEC----CCSEGAAW---GRYCERCPAP 405
+ C + RC + Q+ EC C ++G + Y C P
Sbjct: 765 PCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLP 824
Query: 406 DSAEFMRICQGGMG--RPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDG 463
+ + CQ + PN ++ C+ P+ S+ C C G+ G
Sbjct: 825 YTG---KNCQTVLAPCSPNPCENAAVCKESPNF----------ESYTCLCAPGW----QG 867
Query: 464 LSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF 522
C +D DEC P + +G C NT+G Y C+C PGF+ G D D+D+C
Sbjct: 868 QRCTIDIDECISKPCM-NHGLCHNTQGSYMCECPPGFS-GMDCE-EDIDDCLANPCQNGG 924
Query: 523 RCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + +F C C G+ G C+ D++EC+ EP C + V SY CKC G+
Sbjct: 925 SCMDGVNTFSCLCLPGFT----GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF- 979
Query: 582 RTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPS---EDGTDCIDR 638
D + +INEC E +GG C++ SF C C GF S + +C
Sbjct: 980 ------DGVHCENNINECTE-SSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSH 1032
Query: 639 ---RTGTCYRSLVSGRC 652
GTC L + RC
Sbjct: 1033 PCLNEGTCVDGLGTYRC 1049
Score = 221 bits (539), Expect = 1e-56
Identities = 201/672 (29%), Positives = 286/672 (42%), Gaps = 96/672 (14%)
Query: 21 YLCCCSVGHAWGAPC---EACPPRGSPAHT-ALCGEKP--GEYINPVTNE------TKPI 68
+ C C G A G C +AC +P H ALC P G+YI T+ +
Sbjct: 360 FSCMCPEGKA-GLLCHLDDACI--SNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDV 416
Query: 69 DECDIM-PQLCK-PGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
DEC + C+ G C +T F C C GY D++EC PC+ A C
Sbjct: 417 DECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE---MDINECH--SDPCQNDATC 471
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
++ G F C C PG++ CE +++EC ++G C + + ++C C PG+T
Sbjct: 472 LDKIGGFTCLCMPGFKGV----HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFT-- 525
Query: 186 ENVCR-DVDECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC 243
VC+ D+D+CS C NG C + P Y C C GF + +D C C
Sbjct: 526 GPVCQIDIDDCSSTP--CLNGAKCIDHPNGYECQCATGFTGVLCEENID--NCDPDP--C 579
Query: 244 RNGRCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGGYEC 302
+G+C++ + S+ C C PGY G C D +DEC PC DG C + GY+C
Sbjct: 580 HHGQCQDGIDSYTCICNPGYM----GAICSDQIDEC--YSSPCLNDGR--CIDLVNGYQC 631
Query: 303 SCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE- 360
+C G G C ++ D+C P C G C + Y C C G+ + + +DE
Sbjct: 632 NCQPGTS--GVNCEINFDDCASNP--CIHGICMDGINRYSCVCSPGFTGQR-CNIDIDEC 686
Query: 361 -----RK-ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYC--ERCPAPDSAEFMR 412
RK C + RC P P C C C S +
Sbjct: 687 ASNPCRKGATCINGVNGFRC--ICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSG-YKC 743
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDAD 470
+C G N D +EC P C GG C N +RC C G+ G +C V+ D
Sbjct: 744 LCDAGWVGINCEVDKNECLSNP--CQNGGTCDNLVNGYRCTCKKGF----KGYNCQVNID 797
Query: 471 ECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAG- 529
ECA +P + GTC + GY C C +T QT + C+ C +
Sbjct: 798 ECASNPCL-NQGTCFDDISGYTCHCVLPYTGKNCQTVLA--PCSPNPCENAAVCKESPNF 854
Query: 530 -SFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQ 587
S+ C C G+ G C DIDEC+ +P + C N GSY+C+CP G+ +
Sbjct: 855 ESYTCLCAPGW----QGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGF----SGM 906
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTD---CID---RRTG 641
D E EDI++C +GG C++ +F C C GF + TD C+ + G
Sbjct: 907 DCE---EDIDDC-LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGG 962
Query: 642 TCYRSLVSGRCE 653
TC + S C+
Sbjct: 963 TCSDYVNSYTCK 974
Score = 220 bits (538), Expect = 1e-56
Identities = 179/583 (30%), Positives = 246/583 (42%), Gaps = 72/583 (12%)
Query: 92 CGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLP-GAFECRCPPGYRLTPSLDEC 150
C C G+ ++ + C RP C C L +EC C G+ + EC
Sbjct: 90 CRCASGFTGEDCQYSTSH--PCFVSRP-CLNGGTCHMLSRDTYECTCQVGF----TGKEC 142
Query: 151 EDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGTCEN 209
+ D C + C + C+C G+T ++ C DV+EC P GTC N
Sbjct: 143 QWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQK--CETDVNECDIPGHCQHGGTCLN 200
Query: 210 LPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVG-SFRCECAPGYTLTAD 268
LPG+Y C C GF G D + V C V G CR T +F C C PG+ +
Sbjct: 201 LPGSYQCQCLQGF-TGQYCDSLYV-PCAPSPCV-NGGTCRQTGDFTFECNCLPGF----E 253
Query: 269 GRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV-DRDECKELPY 326
G C R++D+C H C G C + Y C C W G+ C D DEC P
Sbjct: 254 GSTCERNIDDCPN--HRCQNGG--VCVDGVNTYNCRCPPQW--TGQFCTEDVDECLLQPN 307
Query: 327 VCA-GGECRNFNGGYVCECPAGWRFDKTA------AVCVDERKELCYDEWEAGRC---HR 376
C GG C N NGGY C C GW D + A C D + C
Sbjct: 308 ACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEG 367
Query: 377 ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRV-RPD 435
L + C S G C+ P + +++ C G + T+D+DEC + +
Sbjct: 368 KAGLLCHLDDACISNPCHKGALCDTNPL--NGQYICTCPQGYKGADCTEDVDECAMANSN 425
Query: 436 VCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGN-GTCSNTRGGYE 492
C G+CVNTDG+F CEC GY G C +D +EC DP C N TC + GG+
Sbjct: 426 PCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDP--CQNDATCLDKIGGFT 479
Query: 493 CQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DI 551
C C PGF +G ++++EC +C + F+C CP G+ G C+ DI
Sbjct: 480 CLCMPGF-KGV-HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFT----GPVCQIDI 533
Query: 552 DECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVC 611
D+C P + C + Y C+C G+ E+I+ C+ D C G C
Sbjct: 534 DDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCE-------ENIDNCD--PDPCHHGQC 584
Query: 612 INTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS--LVSGRC 652
+ S+ C C+ G+ G C D + CY S L GRC
Sbjct: 585 QDGIDSYTCICNPGYM----GAICSD-QIDECYSSPCLNDGRC 622
Score = 220 bits (538), Expect = 1e-56
Identities = 241/888 (27%), Positives = 341/888 (38%), Gaps = 127/888 (14%)
Query: 20 KYLCCCSVGHAWGAPCEA----CPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMP 75
++ C C G G CE C G H C PG Y CD +
Sbjct: 165 QFSCKCLTGFT-GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTG-QYCDSLY 222
Query: 76 QLCKP------GTCHDTPT-GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
C P GTC T F+C C G+E R++D+C R C+ CV+
Sbjct: 223 VPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCE---RNIDDCPNHR--CQNGGVCVD 277
Query: 129 LPGAFECRCPPGYRLTPSLDEC-EDVDECGDQ-RICDHGD-CRNTIGSYRCECKPGYTLR 185
+ CRCPP + + C EDVDEC Q C +G C N G Y C C G++
Sbjct: 278 GVNTYNCRCPPQW----TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWS-G 332
Query: 186 ENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGP----NNDCVDVNECREGG 240
++ ++D+C+ C G TC + ++ C C +G KAG ++ C+ N C +G
Sbjct: 333 DDCSENIDDCAFAS--CTPGSTCIDRVASFSCMCPEG-KAGLLCHLDDACIS-NPCHKGA 388
Query: 241 MVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDEL-PHPCGRDGNPSCTNTNG 298
+ N G + C C GY G +C DVDEC +PC G C NT+G
Sbjct: 389 LCDTNP----LNGQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGK--CVNTDG 438
Query: 299 GYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRFDKTAAV 356
+ C C G+ G RC +D +EC P C C + GG+ C C G++
Sbjct: 439 AFHCECLKGY--AGPRCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFKGVHCELE 494
Query: 357 CVDERKELCYDEWEA----GRCHRARPLQLARPEC------CCSEGAAWGRYCERCPAPD 406
+ + C + + R P P C C S G C P+
Sbjct: 495 INECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKC--IDHPN 552
Query: 407 SAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
E C G +++D C PD C G+C + S+ C C GY+ G C
Sbjct: 553 GYECQ--CATGFTGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYM----GAIC 604
Query: 467 VDA-DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
D DEC P + +G C + GY+C C PG T G + ++ D+CA C
Sbjct: 605 SDQIDECYSSPCL-NDGRCIDLVNGYQCNCQPG-TSGVNCE-INFDDCASNPCIHGI-CM 660
Query: 526 NTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
+ + C C G+ G C DIDEC P C N V + C CPEG S
Sbjct: 661 DGINRYSCVCSPGFT----GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPS 716
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF---EPSEDGTDCID---R 638
+NEC C G C + C CDAG+ D +C+ +
Sbjct: 717 C-------YSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQ 767
Query: 639 RTGTCYRSLVSG-RCEPEXXXXXXXXXXXXXXXXXX-----XXXXGHVTKAQCCCTLGAA 692
GTC +LV+G RC + ++ C C L
Sbjct: 768 NGGTC-DNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYT 826
Query: 693 WGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECA 752
G C+ AP SP + +P D+DEC
Sbjct: 827 -GKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTI-------DIDECI 878
Query: 753 AIP----GLC--APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCL 805
+ P GLC G + C C PG+ +G C D+D+C P C + ++ CL
Sbjct: 879 SKPCMNHGLCHNTQGSYMCECPPGF--SGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCL 936
Query: 806 CRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
C G+ G C+ D++EC + CS+ SY C C+ G++
Sbjct: 937 CLPGFT----GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD 980
Score = 205 bits (501), Expect = 5e-52
Identities = 177/575 (30%), Positives = 257/575 (44%), Gaps = 90/575 (15%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDV-DECSWGRPPCRGMAQC 126
IDEC P L GTC D +G+ C C Y N C+ V CS PC A C
Sbjct: 796 IDECASNPCL-NQGTCFDDISGYTCHCVLPYTGKN----CQTVLAPCSPN--PCENAAVC 848
Query: 127 VNLPG--AFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYT 183
P ++ C C PG++ C D+DEC + +HG C NT GSY CEC PG++
Sbjct: 849 KESPNFESYTCLCAPGWQG----QRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFS 904
Query: 184 LRENVC-RDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGM 241
+ C D+D+C P G+C + + C C GF + C D+NEC
Sbjct: 905 GMD--CEEDIDDC-LANPCQNGGSCMDGVNTFSCLCLPGF---TGDKCQTDMNECL--SE 956
Query: 242 VCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGG 299
C+N G C + V S+ C+C G+ DG +C +++EC E C G +C +
Sbjct: 957 PCKNGGTCSDYVNSYTCKCQAGF----DGVHCENNINECTE--SSCFNGG--TCVDGINS 1008
Query: 300 YECSCGAGWKLVGRRCV-DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV 358
+ C C G+ G C+ + +EC P + G C + G Y C CP G+ +
Sbjct: 1009 FSCLCPVGF--TGSFCLHEINECSSHPCL-NEGTCVDGLGTYRCSCPLGYTGKNCQTLVN 1065
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
+ C ++ G C + + A +C C G A G YC+ P+ + + + G+
Sbjct: 1066 LCSRSPCKNK---GTCVQKK----AESQCLCPSGWA-GAYCD---VPNVSCDIAASRRGV 1114
Query: 419 GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD-ADECALDPR 477
+L Q G C+N + C+CP GY G C + DECA +P
Sbjct: 1115 LVEHLCQH------------SGVCINAGNTHYCQCPLGYT----GSYCEEQLDECASNP- 1157
Query: 478 ICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCP 536
C +G TCS+ GGY C+C PG+ QG + +VDEC C + F+C+CP
Sbjct: 1158 -CQHGATCSDFIGGYRCECVPGY-QGVNCE-YEVDECQNQPCQNGGTCIDLVNHFKCSCP 1214
Query: 537 YGYAVAADGVHCRD-IDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENAC 593
G G+ C + ID+C + P C + C + +G Y C+C G+ + C
Sbjct: 1215 PG----TRGLLCEENIDDCARGPH-CLNGGQCMDRIGGYSCRCLPGF--------AGERC 1261
Query: 594 E-DINECEEQEDLCSGGV-CINTDGSFLCDCDAGF 626
E DINEC G + CI +LC C + F
Sbjct: 1262 EGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF 1296
Score = 196 bits (479), Expect = 2e-49
Identities = 184/673 (27%), Positives = 265/673 (39%), Gaps = 99/673 (14%)
Query: 21 YLCCCSVGHA-----WGAPCEACPPRGSPAHTALCGEKPGEYINPVTNET--KPIDECDI 73
Y C C VG W C + P T + + + + T + ++ECDI
Sbjct: 129 YECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 188
Query: 74 MPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG-A 132
GTC + P +QC C G+ T C D PC C
Sbjct: 189 PGHCQHGGTCLNLPGSYQCQCLQGF----TGQYC-DSLYVPCAPSPCVNGGTCRQTGDFT 243
Query: 133 FECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRD 191
FEC C PG+ + CE ++D+C + R + G C + + +Y C C P +T + D
Sbjct: 244 FECNCLPGFEGS----TCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWT-GQFCTED 298
Query: 192 VDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVD-VNECREGGMVCRNG-RC 248
VDEC C+N GTC N G Y C C +G+ +DC + +++C C G C
Sbjct: 299 VDECLLQPNACQNGGTCANRNGGYGCVCVNGWS---GDDCSENIDDCAFAS--CTPGSTC 353
Query: 249 RNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
+ V SF C C G G C D C + +PC + NG Y C+C G+
Sbjct: 354 IDRVASFSCMCPEGKA----GLLCHLDDAC--ISNPCHKGALCDTNPLNGQYICTCPQGY 407
Query: 309 KLVGRRCV-DRDECKEL-PYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
K G C D DEC C G+C N +G + CEC G+ R E+
Sbjct: 408 K--GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY---------AGPRCEMD 456
Query: 366 YDEWEAGRCHRARPL--QLARPECCCSEGAAWGRYCE----RC---PAPDSAE------- 409
+E + C ++ C C G G +CE C P ++ +
Sbjct: 457 INECHSDPCQNDATCLDKIGGFTCLCMPGFK-GVHCELEINECQSNPCVNNGQCVDKVNR 515
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
F +C G P D+D+C P C+ G +C++ + C+C G+ G+ C +
Sbjct: 516 FQCLCPPGFTGPVCQIDIDDCSSTP--CLNGAKCIDHPNGYECQCATGFT----GVLCEE 569
Query: 469 -ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHN 526
D C DP C +G C + Y C C+PG+ C D +DEC RC +
Sbjct: 570 NIDNC--DPDPCHHGQCQDGIDSYTCICNPGYM---GAICSDQIDECYSSPCLNDGRCID 624
Query: 527 TAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTS 584
++C C G GV+C + D+C P C H C + + Y C C G+
Sbjct: 625 LVNGYQCNCQPG----TSGVNCEINFDDCASNP--CIHGICMDGINRYSCVCSPGF---- 674
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG-FEPS--EDGTDCIDRRT- 640
+ DI+EC G CIN F C C G PS +C+
Sbjct: 675 ---TGQRCNIDIDEC-ASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCI 730
Query: 641 -GTCYRSLVSGRC 652
G C L +C
Sbjct: 731 HGNCTGGLSGYKC 743
Score = 196 bits (477), Expect = 4e-49
Identities = 172/616 (27%), Positives = 254/616 (41%), Gaps = 102/616 (16%)
Query: 75 PQLCK-PGTCHDTPT--GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG 131
P C+ C ++P + C C G++ + D+DEC PC C N G
Sbjct: 839 PNPCENAAVCKESPNFESYTCLCAPGWQGQRCTI---DIDECI--SKPCMNHGLCHNTQG 893
Query: 132 AFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRD 191
++ C CPPG+ +D ED+D+C + G C + + ++ C C PG+T + D
Sbjct: 894 SYMCECPPGFS---GMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFT-GDKCQTD 949
Query: 192 VDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RC 248
++EC S P C+NG TC + +Y C C GF + ++NEC E C NG C
Sbjct: 950 MNECLSEP---CKNGGTCSDYVNSYTCKCQAGFDGVHCEN--NINECTESS--CFNGGTC 1002
Query: 249 RNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
+ + SF C C G+T G C +++EC HPC +G +C + G Y CSC G
Sbjct: 1003 VDGINSFSCLCPVGFT----GSFCLHEINECSS--HPCLNEG--TCVDGLGTYRCSCPLG 1054
Query: 308 WKLVGRRCVDR-DECKELPYVCAG-GECRNFNGGYVCECPAGWRF------DKTAAVCVD 359
+ G+ C + C P C G C C CP+GW + + +
Sbjct: 1055 Y--TGKNCQTLVNLCSRSP--CKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAAS 1110
Query: 360 ER----KELCYDEW---EAGRCHRAR-PLQLARPEC------CCSEGAAWGRYCERCPAP 405
R + LC AG H + PL C C S G C
Sbjct: 1111 RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGG 1170
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGL 464
E C G N ++DEC+ +P C GG C++ F+C CP G GL
Sbjct: 1171 YRCE----CVPGYQGVNCEYEVDECQNQP--CQNGGTCIDLVNHFKCSCPPG----TRGL 1220
Query: 465 SCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRASC-- 520
C + D+CA P G C + GGY C+C PGF + C D++EC S
Sbjct: 1221 LCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA---GERCEGDINECLSNPCSSEG 1277
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPHAC---ENVVGSYICKC 576
+ C + C C + G HC +D C Q P + C N+ +IC+C
Sbjct: 1278 SLDCIQLTNDYLCVCRSAFT----GRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRC 1333
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC------DCDAG--FEP 628
P G+ +++C + +C + E C++T C DC++G P
Sbjct: 1334 PPGFSGARC----QSSCGQV-KCRKGEQ------CVHTASGPRCFCPSPRDCESGCASSP 1382
Query: 629 SEDGTDCIDRRTGTCY 644
+ G C +R Y
Sbjct: 1383 CQHGGSCHPQRQPPYY 1398
Score = 182 bits (442), Expect = 6e-45
Identities = 193/682 (28%), Positives = 275/682 (40%), Gaps = 101/682 (14%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCE--ACPPRGSPAHTALCGEKPGEYINPVTNETKP 67
C A G T LC ++ + PC C G ++T +C PG Y+ + ++
Sbjct: 556 CQCATGF--TGVLCEENIDNCDPDPCHHGQCQD-GIDSYTCICN--PG-YMGAICSDQ-- 607
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P L G C D G+QC C G N + D+C+ P G+ C+
Sbjct: 608 IDECYSSPCL-NDGRCIDLVNGYQCNCQPGTSGVNCEI---NFDDCA-SNPCIHGI--CM 660
Query: 128 NLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
+ + C C PG+ + C D+DEC C N + +RC C G
Sbjct: 661 DGINRYSCVCSPGF----TGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG-PHHP 715
Query: 187 NVCRDVDEC-SRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN 245
+ V+EC S P C +G C Y C CD G+ G N + VD NEC C+N
Sbjct: 716 SCYSQVNECLSNP---CIHGNCTGGLSGYKCLCDAGW-VGINCE-VDKNECLSNP--CQN 768
Query: 246 G-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECS 303
G C N V +RC C G+ G NC+ ++DEC +PC G +C + GY C
Sbjct: 769 GGTCDNLVNGYRCTCKKGFK----GYNCQVNIDECAS--NPCLNQG--TCFDDISGYTCH 820
Query: 304 CGAGWKLVGRRCVD-RDECKELPYVCAG--GECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
C + G+ C C P A E NF Y C C GW+ + + +DE
Sbjct: 821 CVLPY--TGKNCQTVLAPCSPNPCENAAVCKESPNFES-YTCLCAPGWQGQR-CTIDIDE 876
Query: 361 R-KELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCER----C---PAPDSAE--- 409
+ C + G CH + + C C G + G CE C P +
Sbjct: 877 CISKPCMNH---GLCHNTQGSYM----CECPPGFS-GMDCEEDIDDCLANPCQNGGSCMD 928
Query: 410 ----FMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGL 464
F +C G D++EC P C GG C + S+ C+C G+ DG+
Sbjct: 929 GVNTFSCLCLPGFTGDKCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGF----DGV 982
Query: 465 SCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRASCTF 522
C + +EC + GTC + + C C GFT C+ +++EC+
Sbjct: 983 HCENNINECT-ESSCFNGGTCVDGINSFSCLCPVGFT---GSFCLHEINECSSHPCLNEG 1038
Query: 523 RCHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + G++RC+CP GY G +C+ ++ C + P C C CP G+
Sbjct: 1039 TCVDGLGTYRCSCPLGYT----GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW- 1093
Query: 582 RTSAPQDSENACEDINECEEQ---EDLCS-GGVCINTDGSFLCDCDAGFEPS---EDGTD 634
A D N DI E LC GVCIN + C C G+ S E +
Sbjct: 1094 -AGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDE 1152
Query: 635 CID---RRTGTCYRSLVSGRCE 653
C + TC + RCE
Sbjct: 1153 CASNPCQHGATCSDFIGGYRCE 1174
Score = 176 bits (428), Expect = 3e-43
Identities = 159/549 (28%), Positives = 217/549 (39%), Gaps = 85/549 (15%)
Query: 112 ECSWGRPPCRGMAQCVNLP-GAFECRCPPGYRLTPSLDE-CEDVDECGDQRICDHGDC-- 167
+C G PC CV G C+CP G+ L E C+ D C R + G C
Sbjct: 27 QCRDGYEPCVNEGMCVTYHNGTGYCKCPEGF-----LGEYCQHRDPCEKNRCQNGGTCVA 81
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLP-GAYLCHCDDGFKAGP 226
+ +G C C G+T + C RP GTC L Y C C GF
Sbjct: 82 QAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGF---T 138
Query: 227 NNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHP 284
+C + C C NG C F C+C G+T G+ C DV+ECD +P
Sbjct: 139 GKECQWTDACL--SHPCANGSTCTTVANQFSCKCLTGFT----GQKCETDVNECD-IPGH 191
Query: 285 CGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNG-GYVC 342
C G +C N G Y+C C G+ G+ C D P C GG CR + C
Sbjct: 192 CQHGG--TCLNLPGSYQCQCLQGF--TGQYC-DSLYVPCAPSPCVNGGTCRQTGDFTFEC 246
Query: 343 ECPAGWRFD--------------KTAAVCVDERKEL---CYDEWEAGRCHRARPLQLARP 385
C G+ + VCVD C +W C L +P
Sbjct: 247 NCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP 306
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNT 445
C + G R + + +C G + ++++D+C G C++
Sbjct: 307 NACQNGGTCANR---------NGGYGCVCVNGWSGDDCSENIDDCAF-ASCTPGSTCIDR 356
Query: 446 DGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNT---RGGYECQCSPGFTQG 502
SF C CP+G GL C D C +P C G +T G Y C C G+ +G
Sbjct: 357 VASFSCMCPEGKA----GLLCHLDDACISNP--CHKGALCDTNPLNGQYICTCPQGY-KG 409
Query: 503 PDQTCVDVDECAEGRAS-CTF--RCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEP 558
D T DVDECA ++ C +C NT G+F C C GYA G C DI+EC +P
Sbjct: 410 ADCT-EDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDP 464
Query: 559 RVCPHACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGS 617
C + +G + C C G++ CE +INEC + + G C++
Sbjct: 465 CQNDATCLDKIGGFTCLCMPGFKGVH--------CELEINEC-QSNPCVNNGQCVDKVNR 515
Query: 618 FLCDCDAGF 626
F C C GF
Sbjct: 516 FQCLCPPGF 524
Score = 134 bits (324), Expect = 1e-30
Identities = 127/442 (28%), Positives = 177/442 (40%), Gaps = 56/442 (12%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
GTC D F C C G+ T C +++ECS PC CV+ G + C CP
Sbjct: 1000 GTCVDGINSFSCLCPVGF----TGSFCLHEINECS--SHPCLNEGTCVDGLGTYRCSCPL 1053
Query: 140 GYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYRCECKPG----YTLRENVCRDVDE 194
GY + C+ V+ C + G C +C C G Y NV D+
Sbjct: 1054 GY----TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAA 1109
Query: 195 CSRP---RPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CR 249
R +C++ G C N + C C G+ + +D EC C++G C
Sbjct: 1110 SRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLD--ECASNP--CQHGATCS 1165
Query: 250 NTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
+ +G +RCEC PGY G NC +VDEC PC G +C + ++CSC G
Sbjct: 1166 DFIGGYRCECVPGY----QGVNCEYEVDECQN--QPCQNGG--TCIDLVNHFKCSCPPGT 1217
Query: 309 KLVGRRCVDR-DECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYD 367
+ G C + D+C P+ GG+C + GGY C C G+ ++ + C
Sbjct: 1218 R--GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSS 1275
Query: 368 EWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM-GRPNLTQD 426
E C +QL C A GR+CE D M GG + D
Sbjct: 1276 EGSLD-C-----IQLTNDYLCVCRSAFTGRHCETFV--DVCPQMPCLNGGTCAVASNMPD 1327
Query: 427 LDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV-----DADE-CALDPRICG 480
CR P G RC ++ G +C + V G C D + CA P G
Sbjct: 1328 GFICRCPPGFS-GARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHG 1386
Query: 481 NGTCSNTRGG--YECQCSPGFT 500
G+C R Y CQC+P F+
Sbjct: 1387 -GSCHPQRQPPYYSCQCAPPFS 1407
Score = 108 bits (259), Expect = 9e-23
Identities = 115/442 (26%), Positives = 158/442 (35%), Gaps = 58/442 (13%)
Query: 439 GGRCVNTD--GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSN-TRGGYECQC 495
GG CV G C C G+ + + C + GTC +R YEC C
Sbjct: 76 GGTCVAQAMLGKATCRCASGFT--GEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC 133
Query: 496 SPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDEC 554
GFT + C D C + C A F C C G+ G C D++EC
Sbjct: 134 QVGFT---GKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFT----GQKCETDVNEC 186
Query: 555 VQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCI 612
P C H C N+ GSY C+C +G+ + C+ + +GG C
Sbjct: 187 -DIPGHCQHGGTCLNLPGSYQCQCLQGF--------TGQYCDSLYVPCAPSPCVNGGTCR 237
Query: 613 NT-DGSFLCDCDAGFEPS---EDGTDCIDRRT---GTCYRSL--VSGRCEPEXXXXXXXX 663
T D +F C+C GFE S + DC + R G C + + RC P+
Sbjct: 238 QTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTE 297
Query: 664 XXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSEC-ELCPAPGSPARLDLCTAVNLTPXXX 722
G C +G C +D C + TP
Sbjct: 298 DVDECLLQPNACQNGGT-----CANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGST 352
Query: 723 XXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP----GLCAP----GRFRCVCGPGYRPA 774
L D D C + P LC G++ C C GY+ A
Sbjct: 353 CIDRVASFSCMCPEGKAGLL-CHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGA 410
Query: 775 GEVCADVDECAV-RPPPCDQL--CHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTH 830
+ DVDECA+ PC+ C NTDG++ C C GY G C D++EC D
Sbjct: 411 -DCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDPC 465
Query: 831 TCQQICSNTEGSYECSCEDGYE 852
C + G + C C G++
Sbjct: 466 QNDATCLDKIGGFTCLCMPGFK 487
Score = 97.1 bits (231), Expect = 2e-19
Identities = 107/386 (27%), Positives = 142/386 (36%), Gaps = 74/386 (19%)
Query: 277 ECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGEC--R 334
+C + PC +G + GY C C G+ +G C RD C E GG C +
Sbjct: 27 QCRDGYEPCVNEGMCVTYHNGTGY-CKCPEGF--LGEYCQHRDPC-EKNRCQNGGTCVAQ 82
Query: 335 NFNGGYVCECPAGWRFDKTAAVCVDERKELCYDE---WEAGRCHRARPLQLARPECCCSE 391
G C C +G+ T C C+ G CH L EC C
Sbjct: 83 AMLGKATCRCASGF----TGEDCQYSTSHPCFVSRPCLNGGTCHM---LSRDTYECTCQV 135
Query: 392 GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFR 450
G G+ C Q D C P C G C F
Sbjct: 136 GFT-GKEC-------------------------QWTDACLSHP--CANGSTCTTVANQFS 167
Query: 451 CECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVD 509
C+C G+ G C D +EC + GTC N G Y+CQC GFT Q C
Sbjct: 168 CKCLTGFT----GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFT---GQYCDS 220
Query: 510 V-DECAEGRASCTFRCHNTAG-SFRCTCPYGYAVAADGVHC-RDIDECVQEPRVCPHACE 566
+ CA C T +F C C G+ +G C R+ID+C C
Sbjct: 221 LYVPCAPSPCVNGGTCRQTGDFTFECNCLPGF----EGSTCERNIDDCPNHRCQNGGVCV 276
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENAC-EDINECEEQEDLC-SGGVCINTDGSFLCDCDA 624
+ V +Y C+CP PQ + C ED++EC Q + C +GG C N +G + C C
Sbjct: 277 DGVNTYNCRCP--------PQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVN 328
Query: 625 GFEPSEDGTDCIDRRTGTCYRSLVSG 650
G+ G DC + + S G
Sbjct: 329 GW----SGDDCSENIDDCAFASCTPG 350
Score = 64.5 bits (150), Expect = 2e-09
Identities = 34/98 (34%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 820
+ C+C PG++ G+ C D+DEC +P LCHNT GSY C C G+ G +C
Sbjct: 857 YTCLCAPGWQ--GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGF----SGMDCEE 910
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
D+D+C + C + ++ C C G+ GD C
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGF--TGDKC 946
Score = 60.5 bits (140), Expect = 2e-08
Identities = 35/108 (32%), Positives = 51/108 (47%), Gaps = 12/108 (11%)
Query: 756 GLCAPG--RFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY 810
G+C G + C C P + G+ C DVDEC ++P C C N +G Y C+C G+
Sbjct: 273 GVCVDGVNTYNCRCPPQW--TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGW 330
Query: 811 ELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
D+ N +D+C + T C + S+ C C +G K G C
Sbjct: 331 SGDDCSEN---IDDCAFASCTPGSTCIDRVASFSCMCPEG--KAGLLC 373
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/118 (30%), Positives = 55/118 (46%), Gaps = 14/118 (11%)
Query: 742 LDVFADVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQL 794
+D D+D+C A P G C G F C+C PG+ G+ C D++EC P
Sbjct: 906 MDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGF--TGDKCQTDMNECLSEPCKNGGT 963
Query: 795 CHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C + SY C C+ G+ DG +C +++EC + C + S+ C C G+
Sbjct: 964 CSDYVNSYTCKCQAGF----DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGF 1017
Score = 52.4 bits (120), Expect = 7e-06
Identities = 36/107 (33%), Positives = 46/107 (42%), Gaps = 12/107 (11%)
Query: 756 GLC--APGRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G+C A C C GY G C + +DECA P C + G Y C C GY+
Sbjct: 1124 GVCINAGNTHYCQCPLGY--TGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQ- 1180
Query: 813 DEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
G NC +VDEC+ C + ++CSC G RG C
Sbjct: 1181 ---GVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG--TRGLLC 1222
Score = 52.0 bits (119), Expect = 9e-06
Identities = 69/272 (25%), Positives = 92/272 (33%), Gaps = 41/272 (15%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
ID+C P G C D G+ C C G+ + D++EC G C+
Sbjct: 1226 IDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE---GDINECLSNPCSSEGSLDCI 1282
Query: 128 NLPGAFECRCPPGYRLTPSLDECED-VDECGDQRICDHGDC---RNTIGSYRCECKPGYT 183
L + C C + + CE VD C + G C N + C C PG+
Sbjct: 1283 QLTNDYLCVCRSAF----TGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGF- 1337
Query: 184 LRENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMV 242
+ R C + + CR G C + C C + C + C+ GG
Sbjct: 1338 ---SGARCQSSCGQVK--CRKGEQCVHTASGPRCFCPS--PRDCESGCAS-SPCQHGGS- 1388
Query: 243 CRNGR--------CRNTVGSFRCE--CAPGYT--LTADGRNCRDVDE---CDEL--PHPC 285
C R C RCE AP T T + C D CDE H C
Sbjct: 1389 CHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHAC 1448
Query: 286 GRDGNP-SCTNTNGGYECSCGAG-WKLVGRRC 315
DG S T N CS W + +C
Sbjct: 1449 QWDGGDCSLTMENPWANCSSPLPCWDYINNQC 1480
Score = 42.7 bits (96), Expect = 0.005
Identities = 33/115 (28%), Positives = 53/115 (46%), Gaps = 18/115 (15%)
Query: 747 DVDECAAIP----GLCAP--GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTD 799
D++EC + P G C+ + C C G+ G C + ++EC C +
Sbjct: 949 DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD--GVHCENNINECTESSCFNGGTCVDGI 1006
Query: 800 GSYDCLCRTGYELDEDGANC-RDVDECERDTHTC--QQICSNTEGSYECSCEDGY 851
S+ CLC G+ G+ C +++EC +H C + C + G+Y CSC GY
Sbjct: 1007 NSFSCLCPVGFT----GSFCLHEINECS--SHPCLNEGTCVDGLGTYRCSCPLGY 1055
Score = 41.9 bits (94), Expect = 0.009
Identities = 35/122 (28%), Positives = 49/122 (40%), Gaps = 18/122 (14%)
Query: 747 DVDECAAIP----GLC--APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D +EC + P G C +RC C G++ G C ++DECA P C +
Sbjct: 757 DKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK--GYNCQVNIDECASNPCLNQGTCFDDI 814
Query: 800 GSYDCLCRTGYELDEDGANCRDV-DECERDTHTCQQICSNTEG--SYECSCEDGYEKRGD 856
Y C C Y G NC+ V C + +C + SY C C G++ G
Sbjct: 815 SGYTCHCVLPY----TGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ--GQ 868
Query: 857 AC 858
C
Sbjct: 869 RC 870
>AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein.
Length = 2471
Score = 258 bits (632), Expect = 6e-68
Identities = 238/820 (29%), Positives = 331/820 (40%), Gaps = 113/820 (13%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD-VDECSWGRPPCRGMAQC 126
ID+C P L C D P G++C C G+ T LC + +D C PC QC
Sbjct: 533 IDDCSSTPCL-NGAKCIDHPNGYECQCATGF----TGVLCEENIDNCD--PDPCHH-GQC 584
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
+ ++ C C PGY D+ +DEC + G C + + Y+C C+PG T
Sbjct: 585 QDGIDSYTCICNPGYMGAICSDQ---IDECYSSPCLNDGRCIDLVNGYQCNCQPG-TSGV 640
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
N + D+C+ P C +G C + Y C C GF N +D++EC CR G
Sbjct: 641 NCEINFDDCAS-NP-CIHGICMDGINRYSCVCSPGFTGQRCN--IDIDECASNP--CRKG 694
Query: 247 R-CRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
C N V FRC C G +C V+EC L +PC GN CT GY+C C
Sbjct: 695 ATCINGVNGFRCICPEG----PHHPSCYSQVNEC--LSNPCIH-GN--CTGGLSGYKCLC 745
Query: 305 GAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDE-- 360
AGW VG C VD++EC P C GG C N GY C C G++ V +DE
Sbjct: 746 DAGW--VGINCEVDKNECLSNP--CQNGGTCDNLVNGYRCTCKKGFK-GYNCQVNIDECA 800
Query: 361 -----RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP----APDSAEFM 411
+ C+D+ CH P C CE +P+ +
Sbjct: 801 SNPCLNQGTCFDDISGYTCHCVLPY--TGKNCQTVLAPCSPNPCENAAVCKESPNFESYT 858
Query: 412 RICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCV-DA 469
+C G T D+DEC +P C+ G C NT GS+ CECP G+ G+ C D
Sbjct: 859 CLCAPGWQGQRCTIDIDECISKP--CMNHGLCHNTQGSYMCECPPGF----SGMDCEEDI 912
Query: 470 DECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTA 528
D+C +P C NG +C + + C C PGFT QT D++EC C +
Sbjct: 913 DDCLANP--CQNGGSCMDGVNTFSCLCLPGFTGDKCQT--DMNECLSEPCKNGGTCSDYV 968
Query: 529 GSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQ 587
S+ C C G+ DGVHC + I+EC + C + + S+ C CP G+ +
Sbjct: 969 NSYTCKCQAGF----DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFC-- 1022
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGT--DCIDR----RTG 641
+INEC L + G C++ G++ C C G+ T + R G
Sbjct: 1023 -----LHEINECSSHPCL-NEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKG 1076
Query: 642 TCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQC-----CCTLGAAWGSE 696
TC + +C G + + C C G +
Sbjct: 1077 TCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQ 1136
Query: 697 CELCPAPGS--PARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAI 754
C L GS +LD C A N ++ +VDEC
Sbjct: 1137 CPL-GYTGSYCEEQLDEC-ASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQ 1194
Query: 755 P----GLCAP--GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPC--DQLCHNTDGSYDCL 805
P G C F+C C PG R G +C + +D+CA R P C C + G Y C
Sbjct: 1195 PCQNGGTCIDLVNHFKCSCPPGTR--GLLCEENIDDCA-RGPHCLNGGQCMDRIGGYSCR 1251
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC 845
C G+ + CE D + C ++EGS +C
Sbjct: 1252 CLPGFA----------GERCEGDINECLSNPCSSEGSLDC 1281
Score = 227 bits (556), Expect = 1e-58
Identities = 189/617 (30%), Positives = 272/617 (44%), Gaps = 94/617 (15%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQC 126
I+EC P + G C D FQC C G+ T +C+ D+D+CS PC A+C
Sbjct: 495 INECQSNPCV-NNGQCVDKVNRFQCLCPPGF----TGPVCQIDIDDCS--STPCLNGAKC 547
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
++ P +EC+C G+ T L E E++D C D C HG C++ I SY C C PGY
Sbjct: 548 IDHPNGYECQCATGF--TGVLCE-ENIDNC-DPDPCHHGQCQDGIDSYTCICNPGYM--G 601
Query: 187 NVCRD-VDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN 245
+C D +DEC P +G C +L Y C+C G +G N + ++ ++C C +
Sbjct: 602 AICSDQIDECYSS-PCLNDGRCIDLVNGYQCNCQPG-TSGVNCE-INFDDCASNP--CIH 656
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
G C + + + C C+PG+T G+ C D+DEC +PC R G +C N G+ C C
Sbjct: 657 GICMDGINRYSCVCSPGFT----GQRCNIDIDECAS--NPC-RKG-ATCINGVNGFRCIC 708
Query: 305 GAGWKLVGRRCVDR-DECKELPYVCAGGECRNFNGGYVCECPAGW-----RFDKTAAVCV 358
G C + +EC P C G C GY C C AGW DK +
Sbjct: 709 PEGPHHPS--CYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSN 764
Query: 359 D-ERKELCYDEWEAGRC-----HRARPLQLARPEC----CCSEGAAW---GRYCERCPAP 405
+ C + RC + Q+ EC C ++G + Y C P
Sbjct: 765 PCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLP 824
Query: 406 DSAEFMRICQGGMG--RPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDG 463
+ + CQ + PN ++ C+ P+ S+ C C G+ G
Sbjct: 825 YTG---KNCQTVLAPCSPNPCENAAVCKESPNF----------ESYTCLCAPGW----QG 867
Query: 464 LSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF 522
C +D DEC P + +G C NT+G Y C+C PGF+ G D D+D+C
Sbjct: 868 QRCTIDIDECISKPCM-NHGLCHNTQGSYMCECPPGFS-GMDCE-EDIDDCLANPCQNGG 924
Query: 523 RCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + +F C C G+ G C+ D++EC+ EP C + V SY CKC G+
Sbjct: 925 SCMDGVNTFSCLCLPGFT----GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF- 979
Query: 582 RTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPS---EDGTDCIDR 638
D + +INEC E +GG C++ SF C C GF S + +C
Sbjct: 980 ------DGVHCENNINECTE-SSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSH 1032
Query: 639 ---RTGTCYRSLVSGRC 652
GTC L + RC
Sbjct: 1033 PCLNEGTCVDGLGTYRC 1049
Score = 221 bits (541), Expect = 6e-57
Identities = 179/583 (30%), Positives = 246/583 (42%), Gaps = 72/583 (12%)
Query: 92 CGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLP-GAFECRCPPGYRLTPSLDEC 150
C C G+ ++ + C RP C C L +EC C G+ + EC
Sbjct: 90 CRCASGFTGEDCQYSTSH--PCFVSRP-CLNGGTCHMLSRDTYECTCQVGF----TGKEC 142
Query: 151 EDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGTCEN 209
+ D C + C + C+C G+T ++ C DV+EC P GTC N
Sbjct: 143 QWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQK--CETDVNECDIPGHCQHGGTCLN 200
Query: 210 LPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVG-SFRCECAPGYTLTAD 268
LPG+Y C C GF G D + V C V G CR T +F C C PG+ +
Sbjct: 201 LPGSYQCQCPQGF-TGQYCDSLYV-PCAPSPCV-NGGTCRQTGDFTFECNCLPGF----E 253
Query: 269 GRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV-DRDECKELPY 326
G C R++D+C H C G C + Y C C W G+ C D DEC P
Sbjct: 254 GSTCERNIDDCPN--HRCQNGG--VCVDGVNTYNCRCPPQW--TGQFCTEDVDECLLQPN 307
Query: 327 VCA-GGECRNFNGGYVCECPAGWRFDKTA------AVCVDERKELCYDEWEAGRC---HR 376
C GG C N NGGY C C GW D + A C D + C
Sbjct: 308 ACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEG 367
Query: 377 ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRV-RPD 435
L + C S G C+ P + +++ C G + T+D+DEC + +
Sbjct: 368 KAGLLCHLDDACISNPCHKGALCDTNPL--NGQYICTCPQGYKGADCTEDVDECAMANSN 425
Query: 436 VCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGN-GTCSNTRGGYE 492
C G+CVNTDG+F CEC GY G C +D +EC DP C N TC + GG+
Sbjct: 426 PCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDP--CQNDATCLDKIGGFT 479
Query: 493 CQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DI 551
C C PGF +G ++++EC +C + F+C CP G+ G C+ DI
Sbjct: 480 CLCMPGF-KGV-HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFT----GPVCQIDI 533
Query: 552 DECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVC 611
D+C P + C + Y C+C G+ E+I+ C+ D C G C
Sbjct: 534 DDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCE-------ENIDNCD--PDPCHHGQC 584
Query: 612 INTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS--LVSGRC 652
+ S+ C C+ G+ G C D + CY S L GRC
Sbjct: 585 QDGIDSYTCICNPGYM----GAICSD-QIDECYSSPCLNDGRC 622
Score = 221 bits (539), Expect = 1e-56
Identities = 201/672 (29%), Positives = 286/672 (42%), Gaps = 96/672 (14%)
Query: 21 YLCCCSVGHAWGAPC---EACPPRGSPAHT-ALCGEKP--GEYINPVTNE------TKPI 68
+ C C G A G C +AC +P H ALC P G+YI T+ +
Sbjct: 360 FSCMCPEGKA-GLLCHLDDACI--SNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDV 416
Query: 69 DECDIM-PQLCK-PGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
DEC + C+ G C +T F C C GY D++EC PC+ A C
Sbjct: 417 DECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE---MDINECH--SDPCQNDATC 471
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
++ G F C C PG++ CE +++EC ++G C + + ++C C PG+T
Sbjct: 472 LDKIGGFTCLCMPGFKGV----HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFT-- 525
Query: 186 ENVCR-DVDECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC 243
VC+ D+D+CS C NG C + P Y C C GF + +D C C
Sbjct: 526 GPVCQIDIDDCSSTP--CLNGAKCIDHPNGYECQCATGFTGVLCEENID--NCDPDP--C 579
Query: 244 RNGRCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGGYEC 302
+G+C++ + S+ C C PGY G C D +DEC PC DG C + GY+C
Sbjct: 580 HHGQCQDGIDSYTCICNPGYM----GAICSDQIDEC--YSSPCLNDGR--CIDLVNGYQC 631
Query: 303 SCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE- 360
+C G G C ++ D+C P C G C + Y C C G+ + + +DE
Sbjct: 632 NCQPGTS--GVNCEINFDDCASNP--CIHGICMDGINRYSCVCSPGFTGQR-CNIDIDEC 686
Query: 361 -----RK-ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYC--ERCPAPDSAEFMR 412
RK C + RC P P C C C S +
Sbjct: 687 ASNPCRKGATCINGVNGFRC--ICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSG-YKC 743
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDAD 470
+C G N D +EC P C GG C N +RC C G+ G +C V+ D
Sbjct: 744 LCDAGWVGINCEVDKNECLSNP--CQNGGTCDNLVNGYRCTCKKGF----KGYNCQVNID 797
Query: 471 ECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAG- 529
ECA +P + GTC + GY C C +T QT + C+ C +
Sbjct: 798 ECASNPCL-NQGTCFDDISGYTCHCVLPYTGKNCQTVLA--PCSPNPCENAAVCKESPNF 854
Query: 530 -SFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQ 587
S+ C C G+ G C DIDEC+ +P + C N GSY+C+CP G+ +
Sbjct: 855 ESYTCLCAPGW----QGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGF----SGM 906
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTD---CID---RRTG 641
D E EDI++C +GG C++ +F C C GF + TD C+ + G
Sbjct: 907 DCE---EDIDDC-LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGG 962
Query: 642 TCYRSLVSGRCE 653
TC + S C+
Sbjct: 963 TCSDYVNSYTCK 974
Score = 220 bits (538), Expect = 1e-56
Identities = 241/888 (27%), Positives = 341/888 (38%), Gaps = 127/888 (14%)
Query: 20 KYLCCCSVGHAWGAPCEA----CPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMP 75
++ C C G G CE C G H C PG Y CD +
Sbjct: 165 QFSCKCLTGFT-GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTG-QYCDSLY 222
Query: 76 QLCKP------GTCHDTPT-GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
C P GTC T F+C C G+E R++D+C R C+ CV+
Sbjct: 223 VPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCE---RNIDDCPNHR--CQNGGVCVD 277
Query: 129 LPGAFECRCPPGYRLTPSLDEC-EDVDECGDQ-RICDHGD-CRNTIGSYRCECKPGYTLR 185
+ CRCPP + + C EDVDEC Q C +G C N G Y C C G++
Sbjct: 278 GVNTYNCRCPPQW----TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWS-G 332
Query: 186 ENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGP----NNDCVDVNECREGG 240
++ ++D+C+ C G TC + ++ C C +G KAG ++ C+ N C +G
Sbjct: 333 DDCSENIDDCAFAS--CTPGSTCIDRVASFSCMCPEG-KAGLLCHLDDACIS-NPCHKGA 388
Query: 241 MVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDEL-PHPCGRDGNPSCTNTNG 298
+ N G + C C GY G +C DVDEC +PC G C NT+G
Sbjct: 389 LCDTNP----LNGQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGK--CVNTDG 438
Query: 299 GYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRFDKTAAV 356
+ C C G+ G RC +D +EC P C C + GG+ C C G++
Sbjct: 439 AFHCECLKGY--AGPRCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFKGVHCELE 494
Query: 357 CVDERKELCYDEWEA----GRCHRARPLQLARPEC------CCSEGAAWGRYCERCPAPD 406
+ + C + + R P P C C S G C P+
Sbjct: 495 INECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKC--IDHPN 552
Query: 407 SAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
E C G +++D C PD C G+C + S+ C C GY+ G C
Sbjct: 553 GYECQ--CATGFTGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYM----GAIC 604
Query: 467 VDA-DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
D DEC P + +G C + GY+C C PG T G + ++ D+CA C
Sbjct: 605 SDQIDECYSSPCL-NDGRCIDLVNGYQCNCQPG-TSGVNCE-INFDDCASNPCIHGI-CM 660
Query: 526 NTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
+ + C C G+ G C DIDEC P C N V + C CPEG S
Sbjct: 661 DGINRYSCVCSPGFT----GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPS 716
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF---EPSEDGTDCID---R 638
+NEC C G C + C CDAG+ D +C+ +
Sbjct: 717 C-------YSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQ 767
Query: 639 RTGTCYRSLVSG-RCEPEXXXXXXXXXXXXXXXXXX-----XXXXGHVTKAQCCCTLGAA 692
GTC +LV+G RC + ++ C C L
Sbjct: 768 NGGTC-DNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYT 826
Query: 693 WGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECA 752
G C+ AP SP + +P D+DEC
Sbjct: 827 -GKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTI-------DIDECI 878
Query: 753 AIP----GLC--APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCL 805
+ P GLC G + C C PG+ +G C D+D+C P C + ++ CL
Sbjct: 879 SKPCMNHGLCHNTQGSYMCECPPGF--SGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCL 936
Query: 806 CRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
C G+ G C+ D++EC + CS+ SY C C+ G++
Sbjct: 937 CLPGFT----GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD 980
Score = 205 bits (501), Expect = 5e-52
Identities = 177/575 (30%), Positives = 257/575 (44%), Gaps = 90/575 (15%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDV-DECSWGRPPCRGMAQC 126
IDEC P L GTC D +G+ C C Y N C+ V CS PC A C
Sbjct: 796 IDECASNPCL-NQGTCFDDISGYTCHCVLPYTGKN----CQTVLAPCSPN--PCENAAVC 848
Query: 127 VNLPG--AFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYT 183
P ++ C C PG++ C D+DEC + +HG C NT GSY CEC PG++
Sbjct: 849 KESPNFESYTCLCAPGWQG----QRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFS 904
Query: 184 LRENVC-RDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGM 241
+ C D+D+C P G+C + + C C GF + C D+NEC
Sbjct: 905 GMD--CEEDIDDC-LANPCQNGGSCMDGVNTFSCLCLPGF---TGDKCQTDMNECL--SE 956
Query: 242 VCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGG 299
C+N G C + V S+ C+C G+ DG +C +++EC E C G +C +
Sbjct: 957 PCKNGGTCSDYVNSYTCKCQAGF----DGVHCENNINECTE--SSCFNGG--TCVDGINS 1008
Query: 300 YECSCGAGWKLVGRRCV-DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV 358
+ C C G+ G C+ + +EC P + G C + G Y C CP G+ +
Sbjct: 1009 FSCLCPVGF--TGSFCLHEINECSSHPCL-NEGTCVDGLGTYRCSCPLGYTGKNCQTLVN 1065
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
+ C ++ G C + + A +C C G A G YC+ P+ + + + G+
Sbjct: 1066 LCSRSPCKNK---GTCVQKK----AESQCLCPSGWA-GAYCD---VPNVSCDIAASRRGV 1114
Query: 419 GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD-ADECALDPR 477
+L Q G C+N + C+CP GY G C + DECA +P
Sbjct: 1115 LVEHLCQH------------SGVCINAGNTHYCQCPLGYT----GSYCEEQLDECASNP- 1157
Query: 478 ICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCP 536
C +G TCS+ GGY C+C PG+ QG + +VDEC C + F+C+CP
Sbjct: 1158 -CQHGATCSDFIGGYRCECVPGY-QGVNCE-YEVDECQNQPCQNGGTCIDLVNHFKCSCP 1214
Query: 537 YGYAVAADGVHCRD-IDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENAC 593
G G+ C + ID+C + P C + C + +G Y C+C G+ + C
Sbjct: 1215 PG----TRGLLCEENIDDCARGPH-CLNGGQCMDRIGGYSCRCLPGF--------AGERC 1261
Query: 594 E-DINECEEQEDLCSGGV-CINTDGSFLCDCDAGF 626
E DINEC G + CI +LC C + F
Sbjct: 1262 EGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF 1296
Score = 198 bits (482), Expect = 9e-50
Identities = 184/673 (27%), Positives = 265/673 (39%), Gaps = 99/673 (14%)
Query: 21 YLCCCSVGHA-----WGAPCEACPPRGSPAHTALCGEKPGEYINPVTNET--KPIDECDI 73
Y C C VG W C + P T + + + + T + ++ECDI
Sbjct: 129 YECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 188
Query: 74 MPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG-A 132
GTC + P +QC C G+ T C D PC C
Sbjct: 189 PGHCQHGGTCLNLPGSYQCQCPQGF----TGQYC-DSLYVPCAPSPCVNGGTCRQTGDFT 243
Query: 133 FECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRD 191
FEC C PG+ + CE ++D+C + R + G C + + +Y C C P +T + D
Sbjct: 244 FECNCLPGFEGS----TCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWT-GQFCTED 298
Query: 192 VDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVD-VNECREGGMVCRNG-RC 248
VDEC C+N GTC N G Y C C +G+ +DC + +++C C G C
Sbjct: 299 VDECLLQPNACQNGGTCANRNGGYGCVCVNGWS---GDDCSENIDDCAFAS--CTPGSTC 353
Query: 249 RNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
+ V SF C C G G C D C + +PC + NG Y C+C G+
Sbjct: 354 IDRVASFSCMCPEGKA----GLLCHLDDAC--ISNPCHKGALCDTNPLNGQYICTCPQGY 407
Query: 309 KLVGRRCV-DRDECKEL-PYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
K G C D DEC C G+C N +G + CEC G+ R E+
Sbjct: 408 K--GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY---------AGPRCEMD 456
Query: 366 YDEWEAGRCHRARPL--QLARPECCCSEGAAWGRYCE----RC---PAPDSAE------- 409
+E + C ++ C C G G +CE C P ++ +
Sbjct: 457 INECHSDPCQNDATCLDKIGGFTCLCMPGFK-GVHCELEINECQSNPCVNNGQCVDKVNR 515
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
F +C G P D+D+C P C+ G +C++ + C+C G+ G+ C +
Sbjct: 516 FQCLCPPGFTGPVCQIDIDDCSSTP--CLNGAKCIDHPNGYECQCATGFT----GVLCEE 569
Query: 469 -ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHN 526
D C DP C +G C + Y C C+PG+ C D +DEC RC +
Sbjct: 570 NIDNC--DPDPCHHGQCQDGIDSYTCICNPGYM---GAICSDQIDECYSSPCLNDGRCID 624
Query: 527 TAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTS 584
++C C G GV+C + D+C P C H C + + Y C C G+
Sbjct: 625 LVNGYQCNCQPG----TSGVNCEINFDDCASNP--CIHGICMDGINRYSCVCSPGF---- 674
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG-FEPS--EDGTDCIDRRT- 640
+ DI+EC G CIN F C C G PS +C+
Sbjct: 675 ---TGQRCNIDIDEC-ASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCI 730
Query: 641 -GTCYRSLVSGRC 652
G C L +C
Sbjct: 731 HGNCTGGLSGYKC 743
Score = 196 bits (477), Expect = 4e-49
Identities = 172/616 (27%), Positives = 254/616 (41%), Gaps = 102/616 (16%)
Query: 75 PQLCK-PGTCHDTPT--GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG 131
P C+ C ++P + C C G++ + D+DEC PC C N G
Sbjct: 839 PNPCENAAVCKESPNFESYTCLCAPGWQGQRCTI---DIDECI--SKPCMNHGLCHNTQG 893
Query: 132 AFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRD 191
++ C CPPG+ +D ED+D+C + G C + + ++ C C PG+T + D
Sbjct: 894 SYMCECPPGFS---GMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFT-GDKCQTD 949
Query: 192 VDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RC 248
++EC S P C+NG TC + +Y C C GF + ++NEC E C NG C
Sbjct: 950 MNECLSEP---CKNGGTCSDYVNSYTCKCQAGFDGVHCEN--NINECTESS--CFNGGTC 1002
Query: 249 RNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
+ + SF C C G+T G C +++EC HPC +G +C + G Y CSC G
Sbjct: 1003 VDGINSFSCLCPVGFT----GSFCLHEINECSS--HPCLNEG--TCVDGLGTYRCSCPLG 1054
Query: 308 WKLVGRRCVDR-DECKELPYVCAG-GECRNFNGGYVCECPAGWRF------DKTAAVCVD 359
+ G+ C + C P C G C C CP+GW + + +
Sbjct: 1055 Y--TGKNCQTLVNLCSRSP--CKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAAS 1110
Query: 360 ER----KELCYDEW---EAGRCHRAR-PLQLARPEC------CCSEGAAWGRYCERCPAP 405
R + LC AG H + PL C C S G C
Sbjct: 1111 RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGG 1170
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGL 464
E C G N ++DEC+ +P C GG C++ F+C CP G GL
Sbjct: 1171 YRCE----CVPGYQGVNCEYEVDECQNQP--CQNGGTCIDLVNHFKCSCPPG----TRGL 1220
Query: 465 SCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRASC-- 520
C + D+CA P G C + GGY C+C PGF + C D++EC S
Sbjct: 1221 LCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA---GERCEGDINECLSNPCSSEG 1277
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPHAC---ENVVGSYICKC 576
+ C + C C + G HC +D C Q P + C N+ +IC+C
Sbjct: 1278 SLDCIQLTNDYLCVCRSAFT----GRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRC 1333
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC------DCDAG--FEP 628
P G+ +++C + +C + E C++T C DC++G P
Sbjct: 1334 PPGFSGARC----QSSCGQV-KCRKGEQ------CVHTASGPRCFCPSPRDCESGCASSP 1382
Query: 629 SEDGTDCIDRRTGTCY 644
+ G C +R Y
Sbjct: 1383 CQHGGSCHPQRQPPYY 1398
Score = 182 bits (442), Expect = 6e-45
Identities = 193/682 (28%), Positives = 275/682 (40%), Gaps = 101/682 (14%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCE--ACPPRGSPAHTALCGEKPGEYINPVTNETKP 67
C A G T LC ++ + PC C G ++T +C PG Y+ + ++
Sbjct: 556 CQCATGF--TGVLCEENIDNCDPDPCHHGQCQD-GIDSYTCICN--PG-YMGAICSDQ-- 607
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P L G C D G+QC C G N + D+C+ P G+ C+
Sbjct: 608 IDECYSSPCL-NDGRCIDLVNGYQCNCQPGTSGVNCEI---NFDDCA-SNPCIHGI--CM 660
Query: 128 NLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
+ + C C PG+ + C D+DEC C N + +RC C G
Sbjct: 661 DGINRYSCVCSPGF----TGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG-PHHP 715
Query: 187 NVCRDVDEC-SRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN 245
+ V+EC S P C +G C Y C CD G+ G N + VD NEC C+N
Sbjct: 716 SCYSQVNECLSNP---CIHGNCTGGLSGYKCLCDAGW-VGINCE-VDKNECLSNP--CQN 768
Query: 246 G-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECS 303
G C N V +RC C G+ G NC+ ++DEC +PC G +C + GY C
Sbjct: 769 GGTCDNLVNGYRCTCKKGFK----GYNCQVNIDECAS--NPCLNQG--TCFDDISGYTCH 820
Query: 304 CGAGWKLVGRRCVD-RDECKELPYVCAG--GECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
C + G+ C C P A E NF Y C C GW+ + + +DE
Sbjct: 821 CVLPY--TGKNCQTVLAPCSPNPCENAAVCKESPNFES-YTCLCAPGWQGQR-CTIDIDE 876
Query: 361 R-KELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCER----C---PAPDSAE--- 409
+ C + G CH + + C C G + G CE C P +
Sbjct: 877 CISKPCMNH---GLCHNTQGSYM----CECPPGFS-GMDCEEDIDDCLANPCQNGGSCMD 928
Query: 410 ----FMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGL 464
F +C G D++EC P C GG C + S+ C+C G+ DG+
Sbjct: 929 GVNTFSCLCLPGFTGDKCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGF----DGV 982
Query: 465 SCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRASCTF 522
C + +EC + GTC + + C C GFT C+ +++EC+
Sbjct: 983 HCENNINECT-ESSCFNGGTCVDGINSFSCLCPVGFT---GSFCLHEINECSSHPCLNEG 1038
Query: 523 RCHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + G++RC+CP GY G +C+ ++ C + P C C CP G+
Sbjct: 1039 TCVDGLGTYRCSCPLGYT----GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW- 1093
Query: 582 RTSAPQDSENACEDINECEEQ---EDLCS-GGVCINTDGSFLCDCDAGFEPS---EDGTD 634
A D N DI E LC GVCIN + C C G+ S E +
Sbjct: 1094 -AGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDE 1152
Query: 635 CID---RRTGTCYRSLVSGRCE 653
C + TC + RCE
Sbjct: 1153 CASNPCQHGATCSDFIGGYRCE 1174
Score = 177 bits (430), Expect = 2e-43
Identities = 159/549 (28%), Positives = 217/549 (39%), Gaps = 85/549 (15%)
Query: 112 ECSWGRPPCRGMAQCVNLP-GAFECRCPPGYRLTPSLDE-CEDVDECGDQRICDHGDC-- 167
+C G PC CV G C+CP G+ L E C+ D C R + G C
Sbjct: 27 QCRDGYEPCVNEGMCVTYHNGTGYCKCPEGF-----LGEYCQHRDPCEKNRCQNGGTCVA 81
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLP-GAYLCHCDDGFKAGP 226
+ +G C C G+T + C RP GTC L Y C C GF
Sbjct: 82 QAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGF---T 138
Query: 227 NNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHP 284
+C + C C NG C F C+C G+T G+ C DV+ECD +P
Sbjct: 139 GKECQWTDACL--SHPCANGSTCTTVANQFSCKCLTGFT----GQKCETDVNECD-IPGH 191
Query: 285 CGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNG-GYVC 342
C G +C N G Y+C C G+ G+ C D P C GG CR + C
Sbjct: 192 CQHGG--TCLNLPGSYQCQCPQGF--TGQYC-DSLYVPCAPSPCVNGGTCRQTGDFTFEC 246
Query: 343 ECPAGWRFD--------------KTAAVCVDERKEL---CYDEWEAGRCHRARPLQLARP 385
C G+ + VCVD C +W C L +P
Sbjct: 247 NCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP 306
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNT 445
C + G R + + +C G + ++++D+C G C++
Sbjct: 307 NACQNGGTCANR---------NGGYGCVCVNGWSGDDCSENIDDCAF-ASCTPGSTCIDR 356
Query: 446 DGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNT---RGGYECQCSPGFTQG 502
SF C CP+G GL C D C +P C G +T G Y C C G+ +G
Sbjct: 357 VASFSCMCPEGKA----GLLCHLDDACISNP--CHKGALCDTNPLNGQYICTCPQGY-KG 409
Query: 503 PDQTCVDVDECAEGRAS-CTF--RCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEP 558
D T DVDECA ++ C +C NT G+F C C GYA G C DI+EC +P
Sbjct: 410 ADCT-EDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDP 464
Query: 559 RVCPHACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGS 617
C + +G + C C G++ CE +INEC + + G C++
Sbjct: 465 CQNDATCLDKIGGFTCLCMPGFKGVH--------CELEINEC-QSNPCVNNGQCVDKVNR 515
Query: 618 FLCDCDAGF 626
F C C GF
Sbjct: 516 FQCLCPPGF 524
Score = 134 bits (324), Expect = 1e-30
Identities = 127/442 (28%), Positives = 177/442 (40%), Gaps = 56/442 (12%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
GTC D F C C G+ T C +++ECS PC CV+ G + C CP
Sbjct: 1000 GTCVDGINSFSCLCPVGF----TGSFCLHEINECS--SHPCLNEGTCVDGLGTYRCSCPL 1053
Query: 140 GYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYRCECKPG----YTLRENVCRDVDE 194
GY + C+ V+ C + G C +C C G Y NV D+
Sbjct: 1054 GY----TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAA 1109
Query: 195 CSRP---RPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CR 249
R +C++ G C N + C C G+ + +D EC C++G C
Sbjct: 1110 SRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLD--ECASNP--CQHGATCS 1165
Query: 250 NTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
+ +G +RCEC PGY G NC +VDEC PC G +C + ++CSC G
Sbjct: 1166 DFIGGYRCECVPGY----QGVNCEYEVDECQN--QPCQNGG--TCIDLVNHFKCSCPPGT 1217
Query: 309 KLVGRRCVDR-DECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYD 367
+ G C + D+C P+ GG+C + GGY C C G+ ++ + C
Sbjct: 1218 R--GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSS 1275
Query: 368 EWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM-GRPNLTQD 426
E C +QL C A GR+CE D M GG + D
Sbjct: 1276 EGSLD-C-----IQLTNDYLCVCRSAFTGRHCETFV--DVCPQMPCLNGGTCAVASNMPD 1327
Query: 427 LDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV-----DADE-CALDPRICG 480
CR P G RC ++ G +C + V G C D + CA P G
Sbjct: 1328 GFICRCPPGFS-GARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHG 1386
Query: 481 NGTCSNTRGG--YECQCSPGFT 500
G+C R Y CQC+P F+
Sbjct: 1387 -GSCHPQRQPPYYSCQCAPPFS 1407
Score = 112 bits (269), Expect = 6e-24
Identities = 116/442 (26%), Positives = 159/442 (35%), Gaps = 58/442 (13%)
Query: 439 GGRCVNTD--GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSN-TRGGYECQC 495
GG CV G C C G+ + + C + GTC +R YEC C
Sbjct: 76 GGTCVAQAMLGKATCRCASGFT--GEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC 133
Query: 496 SPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDEC 554
GFT + C D C + C A F C C G+ G C D++EC
Sbjct: 134 QVGFT---GKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFT----GQKCETDVNEC 186
Query: 555 VQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCI 612
P C H C N+ GSY C+CP+G+ + C+ + +GG C
Sbjct: 187 -DIPGHCQHGGTCLNLPGSYQCQCPQGF--------TGQYCDSLYVPCAPSPCVNGGTCR 237
Query: 613 NT-DGSFLCDCDAGFEPS---EDGTDCIDRRT---GTCYRSL--VSGRCEPEXXXXXXXX 663
T D +F C+C GFE S + DC + R G C + + RC P+
Sbjct: 238 QTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTE 297
Query: 664 XXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSEC-ELCPAPGSPARLDLCTAVNLTPXXX 722
G C +G C +D C + TP
Sbjct: 298 DVDECLLQPNACQNGGT-----CANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGST 352
Query: 723 XXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP----GLCAP----GRFRCVCGPGYRPA 774
L D D C + P LC G++ C C GY+ A
Sbjct: 353 CIDRVASFSCMCPEGKAGLL-CHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGA 410
Query: 775 GEVCADVDECAV-RPPPCDQL--CHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTH 830
+ DVDECA+ PC+ C NTDG++ C C GY G C D++EC D
Sbjct: 411 -DCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDPC 465
Query: 831 TCQQICSNTEGSYECSCEDGYE 852
C + G + C C G++
Sbjct: 466 QNDATCLDKIGGFTCLCMPGFK 487
Score = 64.5 bits (150), Expect = 2e-09
Identities = 34/98 (34%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 820
+ C+C PG++ G+ C D+DEC +P LCHNT GSY C C G+ G +C
Sbjct: 857 YTCLCAPGWQ--GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGF----SGMDCEE 910
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
D+D+C + C + ++ C C G+ GD C
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGF--TGDKC 946
Score = 60.5 bits (140), Expect = 2e-08
Identities = 35/108 (32%), Positives = 51/108 (47%), Gaps = 12/108 (11%)
Query: 756 GLCAPG--RFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY 810
G+C G + C C P + G+ C DVDEC ++P C C N +G Y C+C G+
Sbjct: 273 GVCVDGVNTYNCRCPPQW--TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGW 330
Query: 811 ELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
D+ N +D+C + T C + S+ C C +G K G C
Sbjct: 331 SGDDCSEN---IDDCAFASCTPGSTCIDRVASFSCMCPEG--KAGLLC 373
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/118 (30%), Positives = 55/118 (46%), Gaps = 14/118 (11%)
Query: 742 LDVFADVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQL 794
+D D+D+C A P G C G F C+C PG+ G+ C D++EC P
Sbjct: 906 MDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGF--TGDKCQTDMNECLSEPCKNGGT 963
Query: 795 CHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C + SY C C+ G+ DG +C +++EC + C + S+ C C G+
Sbjct: 964 CSDYVNSYTCKCQAGF----DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGF 1017
Score = 52.4 bits (120), Expect = 7e-06
Identities = 36/107 (33%), Positives = 46/107 (42%), Gaps = 12/107 (11%)
Query: 756 GLC--APGRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G+C A C C GY G C + +DECA P C + G Y C C GY+
Sbjct: 1124 GVCINAGNTHYCQCPLGY--TGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQ- 1180
Query: 813 DEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
G NC +VDEC+ C + ++CSC G RG C
Sbjct: 1181 ---GVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG--TRGLLC 1222
Score = 52.0 bits (119), Expect = 9e-06
Identities = 69/272 (25%), Positives = 92/272 (33%), Gaps = 41/272 (15%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
ID+C P G C D G+ C C G+ + D++EC G C+
Sbjct: 1226 IDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE---GDINECLSNPCSSEGSLDCI 1282
Query: 128 NLPGAFECRCPPGYRLTPSLDECED-VDECGDQRICDHGDC---RNTIGSYRCECKPGYT 183
L + C C + + CE VD C + G C N + C C PG+
Sbjct: 1283 QLTNDYLCVCRSAF----TGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGF- 1337
Query: 184 LRENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMV 242
+ R C + + CR G C + C C + C + C+ GG
Sbjct: 1338 ---SGARCQSSCGQVK--CRKGEQCVHTASGPRCFCPS--PRDCESGCAS-SPCQHGGS- 1388
Query: 243 CRNGR--------CRNTVGSFRCE--CAPGYT--LTADGRNCRDVDE---CDEL--PHPC 285
C R C RCE AP T T + C D CDE H C
Sbjct: 1389 CHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHAC 1448
Query: 286 GRDGNP-SCTNTNGGYECSCGAG-WKLVGRRC 315
DG S T N CS W + +C
Sbjct: 1449 QWDGGDCSLTMENPWANCSSPLPCWDYINNQC 1480
Score = 42.7 bits (96), Expect = 0.005
Identities = 33/115 (28%), Positives = 53/115 (46%), Gaps = 18/115 (15%)
Query: 747 DVDECAAIP----GLCAP--GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTD 799
D++EC + P G C+ + C C G+ G C + ++EC C +
Sbjct: 949 DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD--GVHCENNINECTESSCFNGGTCVDGI 1006
Query: 800 GSYDCLCRTGYELDEDGANC-RDVDECERDTHTC--QQICSNTEGSYECSCEDGY 851
S+ CLC G+ G+ C +++EC +H C + C + G+Y CSC GY
Sbjct: 1007 NSFSCLCPVGFT----GSFCLHEINECS--SHPCLNEGTCVDGLGTYRCSCPLGY 1055
Score = 41.9 bits (94), Expect = 0.009
Identities = 35/122 (28%), Positives = 49/122 (40%), Gaps = 18/122 (14%)
Query: 747 DVDECAAIP----GLC--APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D +EC + P G C +RC C G++ G C ++DECA P C +
Sbjct: 757 DKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK--GYNCQVNIDECASNPCLNQGTCFDDI 814
Query: 800 GSYDCLCRTGYELDEDGANCRDV-DECERDTHTCQQICSNTEG--SYECSCEDGYEKRGD 856
Y C C Y G NC+ V C + +C + SY C C G++ G
Sbjct: 815 SGYTCHCVLPY----TGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ--GQ 868
Query: 857 AC 858
C
Sbjct: 869 RC 870
>U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 257 bits (629), Expect = 1e-67
Identities = 256/875 (29%), Positives = 347/875 (39%), Gaps = 130/875 (14%)
Query: 18 QTKYLCCCSVGHAWGAPCEACPPR---GSPAHTALCGEKPGEYINPV------TNETKPI 68
Q +LC C G+ G CE G + A C ++ G++ T I
Sbjct: 412 QGSFLCQCGRGYT-GPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDI 470
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC P + G C D GF C C G+ +T L DVDEC+ PCR A+CV+
Sbjct: 471 DECQSSPCV-NGGVCKDRVNGFSCTCPSGFS-GSTCQL--DVDECA--STPCRNGAKCVD 524
Query: 129 LPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
P +ECRC G+ T C+ +VD+C C HG C + I S+ C C PGYT
Sbjct: 525 QPDGYECRCAEGFEGTL----CDRNVDDCSPDP-CHHGRCVDGIASFSCACAPGYTGTR- 578
Query: 188 VCRD-VDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
C VDEC R +P G C +L YLC C G G N + V++++C C G
Sbjct: 579 -CESQVDEC-RSQPCRHGGKCLDLVDKYLCRCPSG-TTGVNCE-VNIDDCASNP--CTFG 632
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
CR+ + + C C PG+T G C +++EC PCG G SC + G+ C C
Sbjct: 633 VCRDGINRYDCVCQPGFT----GPLCNVEINECAS--SPCGEGG--SCVDGENGFRCLCP 684
Query: 306 AGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
G L C P C+ G C + GG+ C C G
Sbjct: 685 PG-SLPPLCLPPSHPCAHEP--CSHGICYDAPGGFRCVCEPG------------------ 723
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
W RC ++ LAR + C S+ G C + D F C G+ + +
Sbjct: 724 ---WSGPRCSQS----LAR-DACESQPCRAGGTC----SSDGMGFHCTCPPGV-QGRQCE 770
Query: 426 DLDECRVRPDVCV-GGRCVNTDGSFR-CECPDGYVLAPDGLSCV-DADECALDPRICG-N 481
L C P+ C GGRC + G C CP G+ G C D DECA P CG +
Sbjct: 771 LLSPCT--PNPCEHGGRCESAPGQLPVCSCPQGW----QGPRCQQDVDECA-GPAPCGPH 823
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA 540
G C+N G + C C G+T GP +C D+++C C + GSF C+C G+A
Sbjct: 824 GICTNLAGSFSCTCHGGYT-GP--SCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFA 880
Query: 541 VAADGVHC-RDIDECVQEPRVC-PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINE 598
G C RD+DEC+ P C P C + V S+ C CP GY QD + +
Sbjct: 881 ----GPRCARDVDECLSNP--CGPGTCTDHVASFTCTCPPGYGGFHCEQD-------LPD 927
Query: 599 CEEQEDLCSGGVCINTDGSFLCDCDAGFEPSE---DGTDCIDR---RTGTCYRSLVSGRC 652
C +GG C++ SF C C G+ + + C+ R G C + RC
Sbjct: 928 CSPSSCF-NGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRC 986
Query: 653 EP-EXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAW-GSECELCPAPGSPARLD 710
E G + C W G C++ P A
Sbjct: 987 TCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQ 1046
Query: 711 LCTAVN-LTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP----GLCAP--GRF 763
+ + L +VD C A P G C G +
Sbjct: 1047 IGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGY 1106
Query: 764 RCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGY-----ELDEDGA 817
C C PGY G+ C D VDECA +P C + Y C C G E++ED
Sbjct: 1107 MCECLPGYN--GDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDC 1164
Query: 818 NCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
+D R H C + G + C+C GY
Sbjct: 1165 GPGPPLDSGPRCLHN--GTCVDLVGGFRCTCPPGY 1197
Score = 222 bits (542), Expect = 5e-57
Identities = 185/590 (31%), Positives = 248/590 (42%), Gaps = 78/590 (13%)
Query: 81 GTCHDTPTG-FQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGA--FECRC 137
G C P+ C C G+ + C+ D C G RG+ Q + G F CRC
Sbjct: 53 GRCTQLPSREAACLCPPGWVGER----CQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 108
Query: 138 PPGYRLTPSLDECEDVDECGDQRICDHGD-CR-NTIGSYRCECKPGYTLRENVCR-DVDE 194
P G+R P +C D C C HG C G + C C PGY R CR DVDE
Sbjct: 109 PRGFR-GP---DCSLPDPCLSSP-CAHGARCSVGPDGRFLCSCPPGYQGRS--CRSDVDE 161
Query: 195 CSRPRPVCRNGTCENLPGAYLCHCDDGFKAGP--NNDCVDV--NECREGGMVCRNGRCRN 250
C P GTC N PG++ C C G+ GP N V + CR GG ++G
Sbjct: 162 CRVGEPCRHGGTCLNTPGSFRCQCPAGY-TGPLCENPAVPCAPSPCRNGGTCRQSGDL-- 218
Query: 251 TVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
++ C C PG+ +G+NC +VD+C H C G +C + Y C C W
Sbjct: 219 ---TYDCACLPGF----EGQNCEVNVDDCPG--HRCLNGG--TCVDGVNTYNCQCPPEW- 266
Query: 310 LVGRRCV-DRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYD 367
G+ C D DEC+ P C GG C N GG+ C C GW + + D +C+
Sbjct: 267 -TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCF- 324
Query: 368 EWEAGRCH-RARPLQLARPE-----CCCSEGAAWGRYCER---CPA-PDSAEFMRICQGG 417
CH R A P C + A C C P + + C G
Sbjct: 325 --HGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPG 382
Query: 418 MGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALD 475
QD+DEC + + C GRCVNT GSF C+C GY G C D +EC
Sbjct: 383 FTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYT----GPRCETDVNECLSG 438
Query: 476 PRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCT 534
P C N TC + G + C C GFT + VD+DEC C + F CT
Sbjct: 439 P--CRNQATCLDRIGQFTCICMAGFTGTYCE--VDIDECQSSPCVNGGVCKDRVNGFSCT 494
Query: 535 CPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENAC 593
CP G++ G C+ D+DEC P C + Y C+C EG+ T ++
Sbjct: 495 CPSGFS----GSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRN----- 545
Query: 594 EDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
+++C D C G C++ SF C C G+ + + + R+ C
Sbjct: 546 --VDDCSP--DPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPC 591
Score = 208 bits (508), Expect = 6e-53
Identities = 197/643 (30%), Positives = 270/643 (41%), Gaps = 112/643 (17%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCEACPP-RGSP-AHTALCGEKP-GEYIN--PVTNE 64
C +V ++ C C G G C P SP AH A C P G ++ P +
Sbjct: 93 CQSSVVAGTARFSCRCPRGFR-GPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQ 151
Query: 65 TKP----IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+ +DEC + GTC +TP F+C C GY T LC + PC
Sbjct: 152 GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY----TGPLCEN-PAVPCAPSPC 206
Query: 121 RGMAQCVNLPG-AFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCEC 178
R C ++C C PG+ CE +VD+C R + G C + + +Y C+C
Sbjct: 207 RNGGTCRQSGDLTYDCACLPGF----EGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQC 262
Query: 179 KPGYTLRENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECR 237
P +T + DVDEC C N GTC N G + C C +G+ + +D +C
Sbjct: 263 PPEWT-GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNID--DCA 319
Query: 238 EGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
VC +G C + V SF C C G T G C D C + +PC D
Sbjct: 320 TA--VCFHGATCHDRVASFYCACPMGKT----GLLCHLDDAC--VSNPCHEDAICDTNPV 371
Query: 297 NGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRFDKTA 354
NG C+C G+ G C D DEC C G C N G ++C+C G+ T
Sbjct: 372 NGRAICTCPPGF--TGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY----TG 425
Query: 355 AVCVDERKELCYDEWEAGRC-HRARPL-QLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
C E +E +G C ++A L ++ + C C G G YCE
Sbjct: 426 PRC-----ETDVNECLSGPCRNQATCLDRIGQFTCICMAGFT-GTYCE------------ 467
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDAD 470
D+DEC+ P CV GG C + F C CP G+ G +C +D D
Sbjct: 468 ------------VDIDECQSSP--CVNGGVCKDRVNGFSCTCPSGF----SGSTCQLDVD 509
Query: 471 ECALDPRICGNGT-CSNTRGGYECQCSPGFTQGPDQTCVD--VDECAEGRASCTFRCHNT 527
ECA P C NG C + GYEC+C+ GF + T D VD+C+ RC +
Sbjct: 510 ECASTP--CRNGAKCVDQPDGYECRCAEGF----EGTLCDRNVDDCSPDPCH-HGRCVDG 562
Query: 528 AGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTS 584
SF C C GY G C +DEC +P C H C ++V Y+C+CP G +
Sbjct: 563 IASFSCACAPGYT----GTRCESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSGTTGVN 616
Query: 585 APQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
CE +I++C C+ GVC + + C C GF
Sbjct: 617 --------CEVNIDDCASNP--CTFGVCRDGINRYDCVCQPGF 649
Score = 197 bits (480), Expect = 2e-49
Identities = 193/668 (28%), Positives = 265/668 (39%), Gaps = 98/668 (14%)
Query: 20 KYLCCCSVGHAWGAPCEACPP--RGSPAHTALCGE---------KPGEYINPVTNETKPI 68
KYLC C G G CE +P +C + +PG + P+ N I
Sbjct: 603 KYLCRCPSGTT-GVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPG-FTGPLCNVE--I 658
Query: 69 DECDIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+EC P C + G+C D GF+C C G + LC P G+ C
Sbjct: 659 NECASSP--CGEGGSCVDGENGFRCLCPPG----SLPPLCLPPSHPCAHEPCSHGI--CY 710
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
+ PG F C C PG+ P + D C Q G C + + C C PG R+
Sbjct: 711 DAPGGFRCVCEPGWS-GPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQ- 768
Query: 188 VCRDVDECSRPRPVCRNGTCENLPGAY-LCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
C + C+ P P G CE+ PG +C C G++ GP DV+EC +G
Sbjct: 769 -CELLSPCT-PNPCEHGGRCESAPGQLPVCSCPQGWQ-GPRCQ-QDVDECAGPAPCGPHG 824
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C N GSF C C GYT G +C +D+++CD P+PC G SC + G + CSC
Sbjct: 825 ICTNLAGSFSCTCHGGYT----GPSCDQDINDCD--PNPCLNGG--SCQDGVGSFSCSCL 876
Query: 306 AGWKLVGRRCV-DRDECKELPYVCAGGECRNFNGGYVCECPAGW-----RFDK------- 352
G+ G RC D DEC P C G C + + C CP G+ D
Sbjct: 877 PGF--AGPRCARDVDECLSNP--CGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSS 932
Query: 353 --TAAVCVDERKE---LCYDEWEAGRC-HRARPLQLARPECCCSEGAAWGRYCERCPAPD 406
CVD LC + C H A P L+RP C G C A
Sbjct: 933 CFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPC-LSRP---CLHGGV-------CSAAH 981
Query: 407 SAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLS 465
F C P +D C +P C GGRCV T G++ C CP G+ +
Sbjct: 982 PG-FRCTCLESFTGPQCQTLVDWCSRQP--CQNGGRCVQT-GAY-CLCPPGWSGRLCDIR 1036
Query: 466 CVDADECALD-----PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS 519
+ E A ++C G C + + C C G T + +VD C
Sbjct: 1037 SLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQ--EVDPCLAQPCQ 1094
Query: 520 CTFRCHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPH--ACENVVGSYICKC 576
C G + C C GY +G +C D +DEC +P C H +C ++V Y+C C
Sbjct: 1095 HGGTCRGYMGGYMCECLPGY----NGDNCEDDVDECASQP--CQHGGSCIDLVARYLCSC 1148
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCI 636
P G + +E+ C + G C++ G F C C G+ D
Sbjct: 1149 PPGTLGVLC-EINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADIN 1207
Query: 637 DRRTGTCY 644
+ R+G C+
Sbjct: 1208 ECRSGACH 1215
Score = 192 bits (468), Expect = 4e-48
Identities = 181/597 (30%), Positives = 255/597 (42%), Gaps = 101/597 (16%)
Query: 75 PQLCKPG-TCHDTPTGFQ-CGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGA 132
P C+ G C P C C G++ +DVDEC+ G PC C NL G+
Sbjct: 777 PNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQ---QDVDECA-GPAPCGPHGICTNLAGS 832
Query: 133 FECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDV 192
F C C GY PS D+ D+++C + G C++ +GS+ C C PG+ RDV
Sbjct: 833 FSCTCHGGYT-GPSCDQ--DINDCDPNPCLNGGSCQDGVGSFSCSCLPGFA-GPRCARDV 888
Query: 193 DEC-SRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRN 250
DEC S P C GTC + ++ C C G+ G + D+ +C C NG C +
Sbjct: 889 DECLSNP---CGPGTCTDHVASFTCTCPPGY--GGFHCEQDLPDCSPSS--CFNGGTCVD 941
Query: 251 TVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
V SF C C PGYT G +C+ + D C L PC G C+ + G+ C+C +
Sbjct: 942 GVNSFSCLCRPGYT----GAHCQHEADPC--LSRPCLHGG--VCSAAHPGFRCTCLESF- 992
Query: 310 LVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCECPAGWR---FDKTAAVCVDERKEL 364
G +C D C P C GG C G Y C CP GW D + C + ++
Sbjct: 993 -TGPQCQTLVDWCSRQP--CQNGGRCVQ-TGAY-CLCPPGWSGRLCDIRSLPCREAAAQI 1047
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAE--------------F 410
+ + + + C C EG G +CE+ P A+ +
Sbjct: 1048 GVRLEQLCQAGGQCVDEDSSHYCVCPEGRT-GSHCEQEVDPCLAQPCQHGGTCRGYMGGY 1106
Query: 411 MRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VD 468
M C G N D+DEC +P C GG C++ + C CP G + G+ C ++
Sbjct: 1107 MCECLPGYNGDNCEDDVDECASQP--CQHGGSCIDLVARYLCSCPPGTL----GVLCEIN 1160
Query: 469 ADECA----LD--PRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEG--RAS 519
D+C LD PR NGTC + GG+ C C PG+T C D++EC G A+
Sbjct: 1161 EDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT---GLRCEADINECRSGACHAA 1217
Query: 520 CTFRC-HNTAGSFRCTCPYGYAVAADGVHCRDI-DECVQEPRVCPHA--CENVVG----- 570
T C + G FRC C G++ G C+ + C +P C H C G
Sbjct: 1218 HTRDCLQDPGGGFRCLCHAGFS----GPRCQTVLSPCESQP--CQHGGQCRPSPGPGGGL 1271
Query: 571 SYICKCPEGYRRTSAPQDSENACEDI-NECEEQEDLCSGGV-CINTDGSFLCDCDAG 625
++ C C + + P+ CE + C E + C GV C T C C G
Sbjct: 1272 TFTCHCAQPF---WGPR-----CERVARSCRELQ--CPVGVPCQQTPRGPRCACPPG 1318
Score = 176 bits (428), Expect = 3e-43
Identities = 189/663 (28%), Positives = 246/663 (37%), Gaps = 103/663 (15%)
Query: 236 CREGGMVCRNGRCRNTVG-SFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDG--NPS 292
C +G GRC C C PG+ G C+ D C PC G S
Sbjct: 43 CLDGSPCANGGRCTQLPSREAACLCPPGWV----GERCQLEDPCHS--GPCAGRGVCQSS 96
Query: 293 CTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECR-NFNGGYVCECPAGWRF 350
+ C C G++ G C D C P CA G C +G ++C CP G++
Sbjct: 97 VVAGTARFSCRCPRGFR--GPDCSLPDPCLSSP--CAHGARCSVGPDGRFLCSCPPGYQ- 151
Query: 351 DKTAAVCVDERK--ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSA 408
++ VDE + E C G C P C C G G CE P +
Sbjct: 152 GRSCRSDVDECRVGEPCR---HGGTCLNT-PGSF---RCQCPAGYT-GPLCENPAVPCAP 203
Query: 409 EFMRICQGGMGRPN--LTQDL--------DECRVRPDVCVGGRCVN----TDG--SFRCE 452
R GG R + LT D C V D C G RC+N DG ++ C+
Sbjct: 204 SPCR--NGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQ 261
Query: 453 CPDGYVLAPDGLSCV-DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDV 510
CP + G C D DEC L P C NG TC NT GG+ C C G+T + ++
Sbjct: 262 CPPEWT----GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTG--ESCSQNI 315
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN--V 568
D+CA CH+ SF C CP G G+ C D CV P C+ V
Sbjct: 316 DDCATAVCFHGATCHDRVASFYCACPMGKT----GLLCHLDDACVSNPCHEDAICDTNPV 371
Query: 569 VGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP 628
G IC CP G+ + QD + N CE G C+NT GSFLC C G+
Sbjct: 372 NGRAICTCPPGFTGGACDQDVDECSIGANPCEHL------GRCVNTQGSFLCQCGRGYTG 425
Query: 629 SEDGTD---CID---RRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTK 682
TD C+ R TC + C G V K
Sbjct: 426 PRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCK 485
Query: 683 AQ-----CCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXX 737
+ C C G + GS C+L +D C + TP
Sbjct: 486 DRVNGFSCTCPSGFS-GSTCQL--------DVDECAS---TPCRNGAKCVDQPDGYECRC 533
Query: 738 XXXXLDVFAD--VDECAAIP---GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPP 789
D VD+C+ P G C G F C C PGY G C + VDEC +P
Sbjct: 534 AEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGY--TGTRCESQVDECRSQPC 591
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCE 848
C + Y C C +G G NC ++D+C + T +C + Y+C C+
Sbjct: 592 RHGGKCLDLVDKYLCRCPSG----TTGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQ 646
Query: 849 DGY 851
G+
Sbjct: 647 PGF 649
Score = 130 bits (314), Expect = 2e-29
Identities = 158/516 (30%), Positives = 201/516 (38%), Gaps = 90/516 (17%)
Query: 21 YLCCCSVGHAWGAPC--EACPPRGSPA-HTALCGEK-PGEYINPVTNETKPIDECDIMPQ 76
+ C C G+ GA C EA P P H +C PG + + T P +C +
Sbjct: 946 FSCLCRPGYT-GAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGP--QCQTLVD 1002
Query: 77 LCKPGTCHD----TPTGFQCGCDHGYEH---DNTSHLCRDVDECSWGRPP--CRGMAQCV 127
C C + TG C C G+ D S CR+ R C+ QCV
Sbjct: 1003 WCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCV 1062
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD-CRNTIGSYRCECKPGYTLRE 186
+ + C CP G T S E ++VD C Q C HG CR +G Y CEC PGY +
Sbjct: 1063 DEDSSHYCVCPEGR--TGSHCE-QEVDPCLAQP-CQHGGTCRGYMGGYMCECLPGYN-GD 1117
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG----PNNDCVDVNECREGGMV 242
N DVDEC+ +P G+C +L YLC C G +DC G
Sbjct: 1118 NCEDDVDECA-SQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRC 1176
Query: 243 CRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSC-TNTNGGY 300
NG C + VG FRC C PGYT G C D++EC C C + GG+
Sbjct: 1177 LHNGTCVDLVGGFRCTCPPGYT----GLRCEADINECRS--GACHAAHTRDCLQDPGGGF 1230
Query: 301 ECSCGAGWKLVGRRC-VDRDECKELPYVCA-GGECR---NFNGG--YVCECPA---GWRF 350
C C AG+ G RC C+ P C GG+CR GG + C C G R
Sbjct: 1231 RCLCHAGFS--GPRCQTVLSPCESQP--CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRC 1286
Query: 351 DKTAAVCVDERKELCYDEWEAGRCHRARPLQLA--RPECCCSEGAAWGRYCERCPAPDSA 408
++ A C +EL +C P Q P C C G + G C P
Sbjct: 1287 ERVARSC----REL--------QCPVGVPCQQTPRGPRCACPPGLS-GPSCRSFPGSPP- 1332
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRC--VNTDGSFRCECPDGYVLAPDGLS 465
G N + C P C+ GG C FRC C G+ P +
Sbjct: 1333 ----------GASNAS-----CAAAP--CLHGGSCRPAPLAPFFRCACAQGWT-GPRCEA 1374
Query: 466 CVDADECALDPRICGNGTCSNTRGGYEC--QC-SPG 498
A E + +PR C C RG C +C SPG
Sbjct: 1375 PAAAPEVSEEPR-CPRAACQAKRGDQRCDRECNSPG 1409
Score = 125 bits (301), Expect = 8e-28
Identities = 163/564 (28%), Positives = 211/564 (37%), Gaps = 103/564 (18%)
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ 125
+ +DEC P C PGTC D F C C GY H +D+ +CS C
Sbjct: 886 RDVDECLSNP--CGPGTCTDHVASFTCTCPPGY---GGFHCEQDLPDCS--PSSCFNGGT 938
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGD-CRNTIGSYRCECKPGYT 183
CV+ +F C C PGY C+ + D C R C HG C +RC C +T
Sbjct: 939 CVDGVNSFSCLCRPGYTGA----HCQHEADPCLS-RPCLHGGVCSAAHPGFRCTCLESFT 993
Query: 184 LRENVCRD-VDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGG-- 240
+ C+ VD CSR +P G C GAY C C G+ +G D + CRE
Sbjct: 994 GPQ--CQTLVDWCSR-QPCQNGGRCVQT-GAY-CLCPPGW-SGRLCDIRSL-PCREAAAQ 1046
Query: 241 ------MVCR-NGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPS 292
+C+ G+C + S C C G T G +C ++VD C L PC G +
Sbjct: 1047 IGVRLEQLCQAGGQCVDEDSSHYCVCPEGRT----GSHCEQEVDPC--LAQPCQHGG--T 1098
Query: 293 CTNTNGGYECSCGAGWKLVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCECPAGWRF 350
C GGY C C G+ G C D DEC P C GG C + Y+C CP G
Sbjct: 1099 CRGYMGGYMCECLPGYN--GDNCEDDVDECASQP--CQHGGSCIDLVARYLCSCPPG--- 1151
Query: 351 DKTAAVCVDERKELCYD--EWEAG-RC-HRARPLQLA---RPEC--------C------C 389
T V + ++ C ++G RC H + L R C C C
Sbjct: 1152 --TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINEC 1209
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDG- 447
GA + C F +C G P L C +P C GG+C + G
Sbjct: 1210 RSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQP--CQHGGQCRPSPGP 1267
Query: 448 ----SFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
+F C C + G C + + C T G C C PG + GP
Sbjct: 1268 GGGLTFTCHCAQPFW----GPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLS-GP 1322
Query: 504 DQTCVDVDECAEGRASC---------TFRCHNTAGSFRCTCPYGYAVAADGVHCR---DI 551
ASC + R A FRC C G+ G C
Sbjct: 1323 SCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWT----GPRCEAPAAA 1378
Query: 552 DECVQEPRVCPH-ACENVVGSYIC 574
E +EPR CP AC+ G C
Sbjct: 1379 PEVSEEPR-CPRAACQAKRGDQRC 1401
Score = 64.1 bits (149), Expect = 2e-09
Identities = 87/334 (26%), Positives = 120/334 (35%), Gaps = 51/334 (15%)
Query: 72 DIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLP 130
D P+ GTC D GF+C C GY T C D++EC G C+ P
Sbjct: 1171 DSGPRCLHNGTCVDLVGGFRCTCPPGY----TGLRCEADINECRSGACHAAHTRDCLQDP 1226
Query: 131 GA-FECRCPPGYRLTPSLDECEDVDECGDQRICDHG-DCRNTIG-----SYRCEC-KPGY 182
G F C C G+ S C+ V + + C HG CR + G ++ C C +P +
Sbjct: 1227 GGGFRCLCHAGF----SGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFW 1282
Query: 183 TLR-ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF-----KAGPNNDCVDVNEC 236
R E V R E P V C+ P C C G ++ P + N
Sbjct: 1283 GPRCERVARSCRELQCPVGV----PCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNAS 1338
Query: 237 REGGMVCRNGRCRNT--VGSFRCECAPGYT------------LTADGRNCRDVDECDELP 282
G CR FRC CA G+T ++ + R R +
Sbjct: 1339 CAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGD 1398
Query: 283 HPCGRDGN-PSCTNTNGGYECSCGAGWK-LVGRRCVDRDECKELPYVCAGGECRNFNGGY 340
C R+ N P C G S G W+ +C C+ C N
Sbjct: 1399 QRCDRECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDN--- 1455
Query: 341 VCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC 374
+C AG R ++T C ++ C D + GRC
Sbjct: 1456 -FDCHAGGR-ERT---CNPVYEKYCADHFADGRC 1484
Score = 59.3 bits (137), Expect = 6e-08
Identities = 36/114 (31%), Positives = 52/114 (45%), Gaps = 14/114 (12%)
Query: 747 DVDECAAIP----GLCAP--GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
DV+EC + P C G+F C+C G+ G C D+DEC P +C +
Sbjct: 431 DVNECLSGPCRNQATCLDRIGQFTCICMAGF--TGTYCEVDIDECQSSPCVNGGVCKDRV 488
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+ C C +G+ G+ C+ DVDEC C + YEC C +G+E
Sbjct: 489 NGFSCTCPSGFS----GSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFE 538
Score = 58.4 bits (135), Expect = 1e-07
Identities = 40/97 (41%), Positives = 52/97 (53%), Gaps = 12/97 (12%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY--ELDED 815
GRF C C PGY+ G C +DVDEC V PC C NT GS+ C C GY L E+
Sbjct: 140 GRFLCSCPPGYQ--GRSCRSDVDECRV-GEPCRHGGTCLNTPGSFRCQCPAGYTGPLCEN 196
Query: 816 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
A C R+ TC+Q + + +Y+C+C G+E
Sbjct: 197 PAVPCAPSPC-RNGGTCRQ---SGDLTYDCACLPGFE 229
Score = 53.2 bits (122), Expect = 4e-06
Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 14/109 (12%)
Query: 756 GLCAPG--RFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY 810
G C G + C C P + G+ C DVDEC ++P C C NT G + C+C G+
Sbjct: 249 GTCVDGVNTYNCQCPPEW--TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW 306
Query: 811 ELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
G +C +++D+C C + S+ C+C G K G C
Sbjct: 307 ----TGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMG--KTGLLC 349
Score = 52.8 bits (121), Expect = 5e-06
Identities = 32/117 (27%), Positives = 48/117 (41%), Gaps = 15/117 (12%)
Query: 747 DVDECAAIP----GLCAPGR--FRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDG 800
+++ECA+ P G C G FRC+C PG P +C P +C++ G
Sbjct: 657 EINECASSPCGEGGSCVDGENGFRCLCPPGSLPP--LCLPPSHPCAHEPCSHGICYDAPG 714
Query: 801 SYDCLCRTGYELDEDGANCRDV---DECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
+ C+C G+ G C D CE CS+ + C+C G + R
Sbjct: 715 GFRCVCEPGW----SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGR 767
Score = 51.2 bits (117), Expect = 2e-05
Identities = 34/101 (33%), Positives = 45/101 (44%), Gaps = 15/101 (14%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSYD-CLCRTGYELDEDGANC 819
F C C PG + G C + C P PC+ C + G C C G++ G C
Sbjct: 756 FHCTCPPGVQ--GRQCELLSPCT--PNPCEHGGRCESAPGQLPVCSCPQGWQ----GPRC 807
Query: 820 R-DVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDAC 858
+ DVDEC IC+N GS+ C+C GY G +C
Sbjct: 808 QQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGY--TGPSC 846
Score = 45.6 bits (103), Expect = 8e-04
Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 12/103 (11%)
Query: 756 GLC--APGRFRCVCGPGYRPAGEVCADV---DECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
G+C APG FRCVC PG+ +G C+ D C +P C + + C C G
Sbjct: 707 GICYDAPGGFRCVCEPGW--SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGV 764
Query: 811 ELDEDGANCRDVDECERDTHTCQQICSNTEGSYE-CSCEDGYE 852
+ G C + C + C + G CSC G++
Sbjct: 765 Q----GRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQ 803
Score = 44.0 bits (99), Expect = 0.002
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 19/123 (15%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHN 797
DVDEC P C G CVC G+ GE C+ ++D+CA CH+
Sbjct: 274 DVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW--TGESCSQNIDDCATAVCFHGATCHD 331
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSN--TEGSYECSCEDGYEKRG 855
S+ C C G + G C D C + IC G C+C G+ G
Sbjct: 332 RVASFYCACPMG----KTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGF--TG 385
Query: 856 DAC 858
AC
Sbjct: 386 GAC 388
Score = 38.3 bits (85), Expect = 0.11
Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 11/95 (11%)
Query: 765 CVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNT----DGSYDCLCRTGYELDEDGANCR 820
C+C PG+ GE C D C P +C ++ + C C G+ G +C
Sbjct: 65 CLCPPGW--VGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFR----GPDCS 118
Query: 821 DVDECERDTHTCQQICS-NTEGSYECSCEDGYEKR 854
D C CS +G + CSC GY+ R
Sbjct: 119 LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGR 153
Score = 37.9 bits (84), Expect = 0.15
Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 13/78 (16%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDEC---AVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 816
G FRC C PGY G C AD++EC A + G + CLC G+ G
Sbjct: 1187 GGFRCTCPPGY--TGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGF----SG 1240
Query: 817 ANCRDV-DECERDTHTCQ 833
C+ V CE + CQ
Sbjct: 1241 PRCQTVLSPCE--SQPCQ 1256
>AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 257 bits (629), Expect = 1e-67
Identities = 256/875 (29%), Positives = 347/875 (39%), Gaps = 130/875 (14%)
Query: 18 QTKYLCCCSVGHAWGAPCEACPPR---GSPAHTALCGEKPGEYINPV------TNETKPI 68
Q +LC C G+ G CE G + A C ++ G++ T I
Sbjct: 412 QGSFLCQCGRGYT-GPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDI 470
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC P + G C D GF C C G+ +T L DVDEC+ PCR A+CV+
Sbjct: 471 DECQSSPCV-NGGVCKDRVNGFSCTCPSGFS-GSTCQL--DVDECA--STPCRNGAKCVD 524
Query: 129 LPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
P +ECRC G+ T C+ +VD+C C HG C + I S+ C C PGYT
Sbjct: 525 QPDGYECRCAEGFEGTL----CDRNVDDCSPDP-CHHGRCVDGIASFSCACAPGYTGTR- 578
Query: 188 VCRD-VDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
C VDEC R +P G C +L YLC C G G N + V++++C C G
Sbjct: 579 -CESQVDEC-RSQPCRHGGKCLDLVDKYLCRCPSG-TTGVNCE-VNIDDCASNP--CTFG 632
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
CR+ + + C C PG+T G C +++EC PCG G SC + G+ C C
Sbjct: 633 VCRDGINRYDCVCQPGFT----GPLCNVEINECAS--SPCGEGG--SCVDGENGFRCLCP 684
Query: 306 AGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
G L C P C+ G C + GG+ C C G
Sbjct: 685 PG-SLPPLCLPPSHPCAHEP--CSHGICYDAPGGFRCVCEPG------------------ 723
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
W RC ++ LAR + C S+ G C + D F C G+ + +
Sbjct: 724 ---WSGPRCSQS----LAR-DACESQPCRAGGTC----SSDGMGFHCTCPPGV-QGRQCE 770
Query: 426 DLDECRVRPDVCV-GGRCVNTDGSFR-CECPDGYVLAPDGLSCV-DADECALDPRICG-N 481
L C P+ C GGRC + G C CP G+ G C D DECA P CG +
Sbjct: 771 LLSPCT--PNPCEHGGRCESAPGQLPVCSCPQGW----QGPRCQQDVDECA-GPAPCGPH 823
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA 540
G C+N G + C C G+T GP +C D+++C C + GSF C+C G+A
Sbjct: 824 GICTNLAGSFSCTCHGGYT-GP--SCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFA 880
Query: 541 VAADGVHC-RDIDECVQEPRVC-PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINE 598
G C RD+DEC+ P C P C + V S+ C CP GY QD + +
Sbjct: 881 ----GPRCARDVDECLSNP--CGPGTCTDHVASFTCTCPPGYGGFHCEQD-------LPD 927
Query: 599 CEEQEDLCSGGVCINTDGSFLCDCDAGFEPSE---DGTDCIDR---RTGTCYRSLVSGRC 652
C +GG C++ SF C C G+ + + C+ R G C + RC
Sbjct: 928 CSPSSCF-NGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRC 986
Query: 653 EP-EXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAW-GSECELCPAPGSPARLD 710
E G + C W G C++ P A
Sbjct: 987 TCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQ 1046
Query: 711 LCTAVN-LTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP----GLCAP--GRF 763
+ + L +VD C A P G C G +
Sbjct: 1047 IGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGY 1106
Query: 764 RCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGY-----ELDEDGA 817
C C PGY G+ C D VDECA +P C + Y C C G E++ED
Sbjct: 1107 MCECLPGYN--GDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDC 1164
Query: 818 NCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
+D R H C + G + C+C GY
Sbjct: 1165 GPGPPLDSGPRCLHN--GTCVDLVGGFRCTCPPGY 1197
Score = 222 bits (542), Expect = 5e-57
Identities = 185/590 (31%), Positives = 248/590 (42%), Gaps = 78/590 (13%)
Query: 81 GTCHDTPTG-FQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGA--FECRC 137
G C P+ C C G+ + C+ D C G RG+ Q + G F CRC
Sbjct: 53 GRCTQLPSREAACLCPPGWVGER----CQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 108
Query: 138 PPGYRLTPSLDECEDVDECGDQRICDHGD-CR-NTIGSYRCECKPGYTLRENVCR-DVDE 194
P G+R P +C D C C HG C G + C C PGY R CR DVDE
Sbjct: 109 PRGFR-GP---DCSLPDPCLSSP-CAHGARCSVGPDGRFLCSCPPGYQGRS--CRSDVDE 161
Query: 195 CSRPRPVCRNGTCENLPGAYLCHCDDGFKAGP--NNDCVDV--NECREGGMVCRNGRCRN 250
C P GTC N PG++ C C G+ GP N V + CR GG ++G
Sbjct: 162 CRVGEPCRHGGTCLNTPGSFRCQCPAGY-TGPLCENPAVPCAPSPCRNGGTCRQSGDL-- 218
Query: 251 TVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
++ C C PG+ +G+NC +VD+C H C G +C + Y C C W
Sbjct: 219 ---TYDCACLPGF----EGQNCEVNVDDCPG--HRCLNGG--TCVDGVNTYNCQCPPEW- 266
Query: 310 LVGRRCV-DRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYD 367
G+ C D DEC+ P C GG C N GG+ C C GW + + D +C+
Sbjct: 267 -TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCF- 324
Query: 368 EWEAGRCH-RARPLQLARPE-----CCCSEGAAWGRYCER---CPA-PDSAEFMRICQGG 417
CH R A P C + A C C P + + C G
Sbjct: 325 --HGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPG 382
Query: 418 MGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALD 475
QD+DEC + + C GRCVNT GSF C+C GY G C D +EC
Sbjct: 383 FTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYT----GPRCETDVNECLSG 438
Query: 476 PRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCT 534
P C N TC + G + C C GFT + VD+DEC C + F CT
Sbjct: 439 P--CRNQATCLDRIGQFTCICMAGFTGTYCE--VDIDECQSSPCVNGGVCKDRVNGFSCT 494
Query: 535 CPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENAC 593
CP G++ G C+ D+DEC P C + Y C+C EG+ T ++
Sbjct: 495 CPSGFS----GSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRN----- 545
Query: 594 EDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
+++C D C G C++ SF C C G+ + + + R+ C
Sbjct: 546 --VDDCSP--DPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPC 591
Score = 208 bits (508), Expect = 6e-53
Identities = 197/643 (30%), Positives = 270/643 (41%), Gaps = 112/643 (17%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCEACPP-RGSP-AHTALCGEKP-GEYIN--PVTNE 64
C +V ++ C C G G C P SP AH A C P G ++ P +
Sbjct: 93 CQSSVVAGTARFSCRCPRGFR-GPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQ 151
Query: 65 TKP----IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+ +DEC + GTC +TP F+C C GY T LC + PC
Sbjct: 152 GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY----TGPLCEN-PAVPCAPSPC 206
Query: 121 RGMAQCVNLPG-AFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCEC 178
R C ++C C PG+ CE +VD+C R + G C + + +Y C+C
Sbjct: 207 RNGGTCRQSGDLTYDCACLPGF----EGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQC 262
Query: 179 KPGYTLRENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECR 237
P +T + DVDEC C N GTC N G + C C +G+ + +D +C
Sbjct: 263 PPEWT-GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNID--DCA 319
Query: 238 EGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
VC +G C + V SF C C G T G C D C + +PC D
Sbjct: 320 TA--VCFHGATCHDRVASFYCACPMGKT----GLLCHLDDAC--VSNPCHEDAICDTNPV 371
Query: 297 NGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRFDKTA 354
NG C+C G+ G C D DEC C G C N G ++C+C G+ T
Sbjct: 372 NGRAICTCPPGF--TGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY----TG 425
Query: 355 AVCVDERKELCYDEWEAGRC-HRARPL-QLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
C E +E +G C ++A L ++ + C C G G YCE
Sbjct: 426 PRC-----ETDVNECLSGPCRNQATCLDRIGQFTCICMAGFT-GTYCE------------ 467
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDAD 470
D+DEC+ P CV GG C + F C CP G+ G +C +D D
Sbjct: 468 ------------VDIDECQSSP--CVNGGVCKDRVNGFSCTCPSGF----SGSTCQLDVD 509
Query: 471 ECALDPRICGNGT-CSNTRGGYECQCSPGFTQGPDQTCVD--VDECAEGRASCTFRCHNT 527
ECA P C NG C + GYEC+C+ GF + T D VD+C+ RC +
Sbjct: 510 ECASTP--CRNGAKCVDQPDGYECRCAEGF----EGTLCDRNVDDCSPDPCH-HGRCVDG 562
Query: 528 AGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTS 584
SF C C GY G C +DEC +P C H C ++V Y+C+CP G +
Sbjct: 563 IASFSCACAPGYT----GTRCESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSGTTGVN 616
Query: 585 APQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
CE +I++C C+ GVC + + C C GF
Sbjct: 617 --------CEVNIDDCASNP--CTFGVCRDGINRYDCVCQPGF 649
Score = 197 bits (480), Expect = 2e-49
Identities = 193/668 (28%), Positives = 265/668 (39%), Gaps = 98/668 (14%)
Query: 20 KYLCCCSVGHAWGAPCEACPP--RGSPAHTALCGE---------KPGEYINPVTNETKPI 68
KYLC C G G CE +P +C + +PG + P+ N I
Sbjct: 603 KYLCRCPSGTT-GVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPG-FTGPLCNVE--I 658
Query: 69 DECDIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+EC P C + G+C D GF+C C G + LC P G+ C
Sbjct: 659 NECASSP--CGEGGSCVDGENGFRCLCPPG----SLPPLCLPPSHPCAHEPCSHGI--CY 710
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
+ PG F C C PG+ P + D C Q G C + + C C PG R+
Sbjct: 711 DAPGGFRCVCEPGWS-GPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQ- 768
Query: 188 VCRDVDECSRPRPVCRNGTCENLPGAY-LCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
C + C+ P P G CE+ PG +C C G++ GP DV+EC +G
Sbjct: 769 -CELLSPCT-PNPCEHGGRCESAPGQLPVCSCPQGWQ-GPRCQ-QDVDECAGPAPCGPHG 824
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C N GSF C C GYT G +C +D+++CD P+PC G SC + G + CSC
Sbjct: 825 ICTNLAGSFSCTCHGGYT----GPSCDQDINDCD--PNPCLNGG--SCQDGVGSFSCSCL 876
Query: 306 AGWKLVGRRCV-DRDECKELPYVCAGGECRNFNGGYVCECPAGW-----RFDK------- 352
G+ G RC D DEC P C G C + + C CP G+ D
Sbjct: 877 PGF--AGPRCARDVDECLSNP--CGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSS 932
Query: 353 --TAAVCVDERKE---LCYDEWEAGRC-HRARPLQLARPECCCSEGAAWGRYCERCPAPD 406
CVD LC + C H A P L+RP C G C A
Sbjct: 933 CFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPC-LSRP---CLHGGV-------CSAAH 981
Query: 407 SAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLS 465
F C P +D C +P C GGRCV T G++ C CP G+ +
Sbjct: 982 PG-FRCTCLESFTGPQCQTLVDWCSRQP--CQNGGRCVQT-GAY-CLCPPGWSGRLCDIR 1036
Query: 466 CVDADECALD-----PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS 519
+ E A ++C G C + + C C G T + +VD C
Sbjct: 1037 SLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQ--EVDPCLAQPCQ 1094
Query: 520 CTFRCHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPH--ACENVVGSYICKC 576
C G + C C GY +G +C D +DEC +P C H +C ++V Y+C C
Sbjct: 1095 HGGTCRGYMGGYMCECLPGY----NGDNCEDDVDECASQP--CQHGGSCIDLVARYLCSC 1148
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCI 636
P G + +E+ C + G C++ G F C C G+ D
Sbjct: 1149 PPGTLGVLC-EINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADIN 1207
Query: 637 DRRTGTCY 644
+ R+G C+
Sbjct: 1208 ECRSGACH 1215
Score = 192 bits (468), Expect = 4e-48
Identities = 181/597 (30%), Positives = 255/597 (42%), Gaps = 101/597 (16%)
Query: 75 PQLCKPG-TCHDTPTGFQ-CGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGA 132
P C+ G C P C C G++ +DVDEC+ G PC C NL G+
Sbjct: 777 PNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQ---QDVDECA-GPAPCGPHGICTNLAGS 832
Query: 133 FECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDV 192
F C C GY PS D+ D+++C + G C++ +GS+ C C PG+ RDV
Sbjct: 833 FSCTCHGGYT-GPSCDQ--DINDCDPNPCLNGGSCQDGVGSFSCSCLPGFA-GPRCARDV 888
Query: 193 DEC-SRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRN 250
DEC S P C GTC + ++ C C G+ G + D+ +C C NG C +
Sbjct: 889 DECLSNP---CGPGTCTDHVASFTCTCPPGY--GGFHCEQDLPDCSPSS--CFNGGTCVD 941
Query: 251 TVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
V SF C C PGYT G +C+ + D C L PC G C+ + G+ C+C +
Sbjct: 942 GVNSFSCLCRPGYT----GAHCQHEADPC--LSRPCLHGG--VCSAAHPGFRCTCLESF- 992
Query: 310 LVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCECPAGWR---FDKTAAVCVDERKEL 364
G +C D C P C GG C G Y C CP GW D + C + ++
Sbjct: 993 -TGPQCQTLVDWCSRQP--CQNGGRCVQ-TGAY-CLCPPGWSGRLCDIRSLPCREAAAQI 1047
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAE--------------F 410
+ + + + C C EG G +CE+ P A+ +
Sbjct: 1048 GVRLEQLCQAGGQCVDEDSSHYCVCPEGRT-GSHCEQEVDPCLAQPCQHGGTCRGYMGGY 1106
Query: 411 MRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VD 468
M C G N D+DEC +P C GG C++ + C CP G + G+ C ++
Sbjct: 1107 MCECLPGYNGDNCEDDVDECASQP--CQHGGSCIDLVARYLCSCPPGTL----GVLCEIN 1160
Query: 469 ADECA----LD--PRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEG--RAS 519
D+C LD PR NGTC + GG+ C C PG+T C D++EC G A+
Sbjct: 1161 EDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT---GLRCEADINECRSGACHAA 1217
Query: 520 CTFRC-HNTAGSFRCTCPYGYAVAADGVHCRDI-DECVQEPRVCPHA--CENVVG----- 570
T C + G FRC C G++ G C+ + C +P C H C G
Sbjct: 1218 HTRDCLQDPGGGFRCLCHAGFS----GPRCQTVLSPCESQP--CQHGGQCRPSPGPGGGL 1271
Query: 571 SYICKCPEGYRRTSAPQDSENACEDI-NECEEQEDLCSGGV-CINTDGSFLCDCDAG 625
++ C C + + P+ CE + C E + C GV C T C C G
Sbjct: 1272 TFTCHCAQPF---WGPR-----CERVARSCRELQ--CPVGVPCQQTPRGPRCACPPG 1318
Score = 176 bits (428), Expect = 3e-43
Identities = 189/663 (28%), Positives = 246/663 (37%), Gaps = 103/663 (15%)
Query: 236 CREGGMVCRNGRCRNTVG-SFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDG--NPS 292
C +G GRC C C PG+ G C+ D C PC G S
Sbjct: 43 CLDGSPCANGGRCTQLPSREAACLCPPGWV----GERCQLEDPCHS--GPCAGRGVCQSS 96
Query: 293 CTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECR-NFNGGYVCECPAGWRF 350
+ C C G++ G C D C P CA G C +G ++C CP G++
Sbjct: 97 VVAGTARFSCRCPRGFR--GPDCSLPDPCLSSP--CAHGARCSVGPDGRFLCSCPPGYQ- 151
Query: 351 DKTAAVCVDERK--ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSA 408
++ VDE + E C G C P C C G G CE P +
Sbjct: 152 GRSCRSDVDECRVGEPCR---HGGTCLNT-PGSF---RCQCPAGYT-GPLCENPAVPCAP 203
Query: 409 EFMRICQGGMGRPN--LTQDL--------DECRVRPDVCVGGRCVN----TDG--SFRCE 452
R GG R + LT D C V D C G RC+N DG ++ C+
Sbjct: 204 SPCR--NGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQ 261
Query: 453 CPDGYVLAPDGLSCV-DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDV 510
CP + G C D DEC L P C NG TC NT GG+ C C G+T + ++
Sbjct: 262 CPPEWT----GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTG--ESCSQNI 315
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN--V 568
D+CA CH+ SF C CP G G+ C D CV P C+ V
Sbjct: 316 DDCATAVCFHGATCHDRVASFYCACPMGKT----GLLCHLDDACVSNPCHEDAICDTNPV 371
Query: 569 VGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP 628
G IC CP G+ + QD + N CE G C+NT GSFLC C G+
Sbjct: 372 NGRAICTCPPGFTGGACDQDVDECSIGANPCEHL------GRCVNTQGSFLCQCGRGYTG 425
Query: 629 SEDGTD---CID---RRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTK 682
TD C+ R TC + C G V K
Sbjct: 426 PRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCK 485
Query: 683 AQ-----CCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXX 737
+ C C G + GS C+L +D C + TP
Sbjct: 486 DRVNGFSCTCPSGFS-GSTCQL--------DVDECAS---TPCRNGAKCVDQPDGYECRC 533
Query: 738 XXXXLDVFAD--VDECAAIP---GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPP 789
D VD+C+ P G C G F C C PGY G C + VDEC +P
Sbjct: 534 AEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGY--TGTRCESQVDECRSQPC 591
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCE 848
C + Y C C +G G NC ++D+C + T +C + Y+C C+
Sbjct: 592 RHGGKCLDLVDKYLCRCPSG----TTGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQ 646
Query: 849 DGY 851
G+
Sbjct: 647 PGF 649
Score = 130 bits (314), Expect = 2e-29
Identities = 158/516 (30%), Positives = 201/516 (38%), Gaps = 90/516 (17%)
Query: 21 YLCCCSVGHAWGAPC--EACPPRGSPA-HTALCGEK-PGEYINPVTNETKPIDECDIMPQ 76
+ C C G+ GA C EA P P H +C PG + + T P +C +
Sbjct: 946 FSCLCRPGYT-GAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGP--QCQTLVD 1002
Query: 77 LCKPGTCHD----TPTGFQCGCDHGYEH---DNTSHLCRDVDECSWGRPP--CRGMAQCV 127
C C + TG C C G+ D S CR+ R C+ QCV
Sbjct: 1003 WCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCV 1062
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD-CRNTIGSYRCECKPGYTLRE 186
+ + C CP G T S E ++VD C Q C HG CR +G Y CEC PGY +
Sbjct: 1063 DEDSSHYCVCPEGR--TGSHCE-QEVDPCLAQP-CQHGGTCRGYMGGYMCECLPGYN-GD 1117
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG----PNNDCVDVNECREGGMV 242
N DVDEC+ +P G+C +L YLC C G +DC G
Sbjct: 1118 NCEDDVDECA-SQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRC 1176
Query: 243 CRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSC-TNTNGGY 300
NG C + VG FRC C PGYT G C D++EC C C + GG+
Sbjct: 1177 LHNGTCVDLVGGFRCTCPPGYT----GLRCEADINECRS--GACHAAHTRDCLQDPGGGF 1230
Query: 301 ECSCGAGWKLVGRRC-VDRDECKELPYVCA-GGECR---NFNGG--YVCECPA---GWRF 350
C C AG+ G RC C+ P C GG+CR GG + C C G R
Sbjct: 1231 RCLCHAGFS--GPRCQTVLSPCESQP--CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRC 1286
Query: 351 DKTAAVCVDERKELCYDEWEAGRCHRARPLQLA--RPECCCSEGAAWGRYCERCPAPDSA 408
++ A C +EL +C P Q P C C G + G C P
Sbjct: 1287 ERVARSC----REL--------QCPVGVPCQQTPRGPRCACPPGLS-GPSCRSFPGSPP- 1332
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRC--VNTDGSFRCECPDGYVLAPDGLS 465
G N + C P C+ GG C FRC C G+ P +
Sbjct: 1333 ----------GASNAS-----CAAAP--CLHGGSCRPAPLAPFFRCACAQGWT-GPRCEA 1374
Query: 466 CVDADECALDPRICGNGTCSNTRGGYEC--QC-SPG 498
A E + +PR C C RG C +C SPG
Sbjct: 1375 PAAAPEVSEEPR-CPRAACQAKRGDQRCDRECNSPG 1409
Score = 125 bits (301), Expect = 8e-28
Identities = 163/564 (28%), Positives = 211/564 (37%), Gaps = 103/564 (18%)
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ 125
+ +DEC P C PGTC D F C C GY H +D+ +CS C
Sbjct: 886 RDVDECLSNP--CGPGTCTDHVASFTCTCPPGY---GGFHCEQDLPDCS--PSSCFNGGT 938
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGD-CRNTIGSYRCECKPGYT 183
CV+ +F C C PGY C+ + D C R C HG C +RC C +T
Sbjct: 939 CVDGVNSFSCLCRPGYTGA----HCQHEADPCLS-RPCLHGGVCSAAHPGFRCTCLESFT 993
Query: 184 LRENVCRD-VDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGG-- 240
+ C+ VD CSR +P G C GAY C C G+ +G D + CRE
Sbjct: 994 GPQ--CQTLVDWCSR-QPCQNGGRCVQT-GAY-CLCPPGW-SGRLCDIRSL-PCREAAAQ 1046
Query: 241 ------MVCR-NGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPS 292
+C+ G+C + S C C G T G +C ++VD C L PC G +
Sbjct: 1047 IGVRLEQLCQAGGQCVDEDSSHYCVCPEGRT----GSHCEQEVDPC--LAQPCQHGG--T 1098
Query: 293 CTNTNGGYECSCGAGWKLVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCECPAGWRF 350
C GGY C C G+ G C D DEC P C GG C + Y+C CP G
Sbjct: 1099 CRGYMGGYMCECLPGYN--GDNCEDDVDECASQP--CQHGGSCIDLVARYLCSCPPG--- 1151
Query: 351 DKTAAVCVDERKELCYD--EWEAG-RC-HRARPLQLA---RPEC--------C------C 389
T V + ++ C ++G RC H + L R C C C
Sbjct: 1152 --TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINEC 1209
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDG- 447
GA + C F +C G P L C +P C GG+C + G
Sbjct: 1210 RSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQP--CQHGGQCRPSPGP 1267
Query: 448 ----SFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
+F C C + G C + + C T G C C PG + GP
Sbjct: 1268 GGGLTFTCHCAQPFW----GPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLS-GP 1322
Query: 504 DQTCVDVDECAEGRASC---------TFRCHNTAGSFRCTCPYGYAVAADGVHCR---DI 551
ASC + R A FRC C G+ G C
Sbjct: 1323 SCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWT----GPRCEAPAAA 1378
Query: 552 DECVQEPRVCPH-ACENVVGSYIC 574
E +EPR CP AC+ G C
Sbjct: 1379 PEVSEEPR-CPRAACQAKRGDQRC 1401
Score = 64.1 bits (149), Expect = 2e-09
Identities = 87/334 (26%), Positives = 120/334 (35%), Gaps = 51/334 (15%)
Query: 72 DIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLP 130
D P+ GTC D GF+C C GY T C D++EC G C+ P
Sbjct: 1171 DSGPRCLHNGTCVDLVGGFRCTCPPGY----TGLRCEADINECRSGACHAAHTRDCLQDP 1226
Query: 131 GA-FECRCPPGYRLTPSLDECEDVDECGDQRICDHG-DCRNTIG-----SYRCEC-KPGY 182
G F C C G+ S C+ V + + C HG CR + G ++ C C +P +
Sbjct: 1227 GGGFRCLCHAGF----SGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFW 1282
Query: 183 TLR-ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF-----KAGPNNDCVDVNEC 236
R E V R E P V C+ P C C G ++ P + N
Sbjct: 1283 GPRCERVARSCRELQCPVGV----PCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNAS 1338
Query: 237 REGGMVCRNGRCRNT--VGSFRCECAPGYT------------LTADGRNCRDVDECDELP 282
G CR FRC CA G+T ++ + R R +
Sbjct: 1339 CAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGD 1398
Query: 283 HPCGRDGN-PSCTNTNGGYECSCGAGWK-LVGRRCVDRDECKELPYVCAGGECRNFNGGY 340
C R+ N P C G S G W+ +C C+ C N
Sbjct: 1399 QRCDRECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDN--- 1455
Query: 341 VCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC 374
+C AG R ++T C ++ C D + GRC
Sbjct: 1456 -FDCHAGGR-ERT---CNPVYEKYCADHFADGRC 1484
Score = 59.3 bits (137), Expect = 6e-08
Identities = 36/114 (31%), Positives = 52/114 (45%), Gaps = 14/114 (12%)
Query: 747 DVDECAAIP----GLCAP--GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
DV+EC + P C G+F C+C G+ G C D+DEC P +C +
Sbjct: 431 DVNECLSGPCRNQATCLDRIGQFTCICMAGF--TGTYCEVDIDECQSSPCVNGGVCKDRV 488
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+ C C +G+ G+ C+ DVDEC C + YEC C +G+E
Sbjct: 489 NGFSCTCPSGFS----GSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFE 538
Score = 58.4 bits (135), Expect = 1e-07
Identities = 40/97 (41%), Positives = 52/97 (53%), Gaps = 12/97 (12%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY--ELDED 815
GRF C C PGY+ G C +DVDEC V PC C NT GS+ C C GY L E+
Sbjct: 140 GRFLCSCPPGYQ--GRSCRSDVDECRV-GEPCRHGGTCLNTPGSFRCQCPAGYTGPLCEN 196
Query: 816 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
A C R+ TC+Q + + +Y+C+C G+E
Sbjct: 197 PAVPCAPSPC-RNGGTCRQ---SGDLTYDCACLPGFE 229
Score = 53.2 bits (122), Expect = 4e-06
Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 14/109 (12%)
Query: 756 GLCAPG--RFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY 810
G C G + C C P + G+ C DVDEC ++P C C NT G + C+C G+
Sbjct: 249 GTCVDGVNTYNCQCPPEW--TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW 306
Query: 811 ELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
G +C +++D+C C + S+ C+C G K G C
Sbjct: 307 ----TGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMG--KTGLLC 349
Score = 52.8 bits (121), Expect = 5e-06
Identities = 32/117 (27%), Positives = 48/117 (41%), Gaps = 15/117 (12%)
Query: 747 DVDECAAIP----GLCAPGR--FRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDG 800
+++ECA+ P G C G FRC+C PG P +C P +C++ G
Sbjct: 657 EINECASSPCGEGGSCVDGENGFRCLCPPGSLPP--LCLPPSHPCAHEPCSHGICYDAPG 714
Query: 801 SYDCLCRTGYELDEDGANCRDV---DECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
+ C+C G+ G C D CE CS+ + C+C G + R
Sbjct: 715 GFRCVCEPGW----SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGR 767
Score = 51.2 bits (117), Expect = 2e-05
Identities = 34/101 (33%), Positives = 45/101 (44%), Gaps = 15/101 (14%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSYD-CLCRTGYELDEDGANC 819
F C C PG + G C + C P PC+ C + G C C G++ G C
Sbjct: 756 FHCTCPPGVQ--GRQCELLSPCT--PNPCEHGGRCESAPGQLPVCSCPQGWQ----GPRC 807
Query: 820 R-DVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDAC 858
+ DVDEC IC+N GS+ C+C GY G +C
Sbjct: 808 QQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGY--TGPSC 846
Score = 45.6 bits (103), Expect = 8e-04
Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 12/103 (11%)
Query: 756 GLC--APGRFRCVCGPGYRPAGEVCADV---DECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
G+C APG FRCVC PG+ +G C+ D C +P C + + C C G
Sbjct: 707 GICYDAPGGFRCVCEPGW--SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGV 764
Query: 811 ELDEDGANCRDVDECERDTHTCQQICSNTEGSYE-CSCEDGYE 852
+ G C + C + C + G CSC G++
Sbjct: 765 Q----GRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQ 803
Score = 44.0 bits (99), Expect = 0.002
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 19/123 (15%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHN 797
DVDEC P C G CVC G+ GE C+ ++D+CA CH+
Sbjct: 274 DVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW--TGESCSQNIDDCATAVCFHGATCHD 331
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSN--TEGSYECSCEDGYEKRG 855
S+ C C G + G C D C + IC G C+C G+ G
Sbjct: 332 RVASFYCACPMG----KTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGF--TG 385
Query: 856 DAC 858
AC
Sbjct: 386 GAC 388
Score = 38.3 bits (85), Expect = 0.11
Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 11/95 (11%)
Query: 765 CVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNT----DGSYDCLCRTGYELDEDGANCR 820
C+C PG+ GE C D C P +C ++ + C C G+ G +C
Sbjct: 65 CLCPPGW--VGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFR----GPDCS 118
Query: 821 DVDECERDTHTCQQICS-NTEGSYECSCEDGYEKR 854
D C CS +G + CSC GY+ R
Sbjct: 119 LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGR 153
Score = 37.9 bits (84), Expect = 0.15
Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 13/78 (16%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDEC---AVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 816
G FRC C PGY G C AD++EC A + G + CLC G+ G
Sbjct: 1187 GGFRCTCPPGY--TGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGF----SG 1240
Query: 817 ANCRDV-DECERDTHTCQ 833
C+ V CE + CQ
Sbjct: 1241 PRCQTVLSPCE--SQPCQ 1256
>AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.
Length = 2281
Score = 257 bits (629), Expect = 1e-67
Identities = 256/875 (29%), Positives = 347/875 (39%), Gaps = 130/875 (14%)
Query: 18 QTKYLCCCSVGHAWGAPCEACPPR---GSPAHTALCGEKPGEYINPV------TNETKPI 68
Q +LC C G+ G CE G + A C ++ G++ T I
Sbjct: 372 QGSFLCQCGRGYT-GPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDI 430
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC P + G C D GF C C G+ +T L DVDEC+ PCR A+CV+
Sbjct: 431 DECQSSPCV-NGGVCKDRVNGFSCTCPSGFS-GSTCQL--DVDECA--STPCRNGAKCVD 484
Query: 129 LPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
P +ECRC G+ T C+ +VD+C C HG C + I S+ C C PGYT
Sbjct: 485 QPDGYECRCAEGFEGTL----CDRNVDDCSPDP-CHHGRCVDGIASFSCACAPGYTGTR- 538
Query: 188 VCRD-VDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
C VDEC R +P G C +L YLC C G G N + V++++C C G
Sbjct: 539 -CESQVDEC-RSQPCRHGGKCLDLVDKYLCRCPSG-TTGVNCE-VNIDDCASNP--CTFG 592
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
CR+ + + C C PG+T G C +++EC PCG G SC + G+ C C
Sbjct: 593 VCRDGINRYDCVCQPGFT----GPLCNVEINECAS--SPCGEGG--SCVDGENGFRCLCP 644
Query: 306 AGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
G L C P C+ G C + GG+ C C G
Sbjct: 645 PG-SLPPLCLPPSHPCAHEP--CSHGICYDAPGGFRCVCEPG------------------ 683
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
W RC ++ LAR + C S+ G C + D F C G+ + +
Sbjct: 684 ---WSGPRCSQS----LAR-DACESQPCRAGGTC----SSDGMGFHCTCPPGV-QGRQCE 730
Query: 426 DLDECRVRPDVCV-GGRCVNTDGSFR-CECPDGYVLAPDGLSCV-DADECALDPRICG-N 481
L C P+ C GGRC + G C CP G+ G C D DECA P CG +
Sbjct: 731 LLSPCT--PNPCEHGGRCESAPGQLPVCSCPQGW----QGPRCQQDVDECA-GPAPCGPH 783
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA 540
G C+N G + C C G+T GP +C D+++C C + GSF C+C G+A
Sbjct: 784 GICTNLAGSFSCTCHGGYT-GP--SCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFA 840
Query: 541 VAADGVHC-RDIDECVQEPRVC-PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINE 598
G C RD+DEC+ P C P C + V S+ C CP GY QD + +
Sbjct: 841 ----GPRCARDVDECLSNP--CGPGTCTDHVASFTCTCPPGYGGFHCEQD-------LPD 887
Query: 599 CEEQEDLCSGGVCINTDGSFLCDCDAGFEPSE---DGTDCIDR---RTGTCYRSLVSGRC 652
C +GG C++ SF C C G+ + + C+ R G C + RC
Sbjct: 888 CSPSSCF-NGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRC 946
Query: 653 EP-EXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAW-GSECELCPAPGSPARLD 710
E G + C W G C++ P A
Sbjct: 947 TCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQ 1006
Query: 711 LCTAVN-LTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP----GLCAP--GRF 763
+ + L +VD C A P G C G +
Sbjct: 1007 IGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGY 1066
Query: 764 RCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGY-----ELDEDGA 817
C C PGY G+ C D VDECA +P C + Y C C G E++ED
Sbjct: 1067 MCECLPGYN--GDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDC 1124
Query: 818 NCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
+D R H C + G + C+C GY
Sbjct: 1125 GPGPPLDSGPRCLHN--GTCVDLVGGFRCTCPPGY 1157
Score = 222 bits (542), Expect = 5e-57
Identities = 185/590 (31%), Positives = 248/590 (42%), Gaps = 78/590 (13%)
Query: 81 GTCHDTPTG-FQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGA--FECRC 137
G C P+ C C G+ + C+ D C G RG+ Q + G F CRC
Sbjct: 13 GRCTQLPSREAACLCPPGWVGER----CQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 68
Query: 138 PPGYRLTPSLDECEDVDECGDQRICDHGD-CR-NTIGSYRCECKPGYTLRENVCR-DVDE 194
P G+R P +C D C C HG C G + C C PGY R CR DVDE
Sbjct: 69 PRGFR-GP---DCSLPDPCLSSP-CAHGARCSVGPDGRFLCSCPPGYQGRS--CRSDVDE 121
Query: 195 CSRPRPVCRNGTCENLPGAYLCHCDDGFKAGP--NNDCVDV--NECREGGMVCRNGRCRN 250
C P GTC N PG++ C C G+ GP N V + CR GG ++G
Sbjct: 122 CRVGEPCRHGGTCLNTPGSFRCQCPAGY-TGPLCENPAVPCAPSPCRNGGTCRQSGDL-- 178
Query: 251 TVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
++ C C PG+ +G+NC +VD+C H C G +C + Y C C W
Sbjct: 179 ---TYDCACLPGF----EGQNCEVNVDDCPG--HRCLNGG--TCVDGVNTYNCQCPPEW- 226
Query: 310 LVGRRCV-DRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYD 367
G+ C D DEC+ P C GG C N GG+ C C GW + + D +C+
Sbjct: 227 -TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCF- 284
Query: 368 EWEAGRCH-RARPLQLARPE-----CCCSEGAAWGRYCER---CPA-PDSAEFMRICQGG 417
CH R A P C + A C C P + + C G
Sbjct: 285 --HGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPG 342
Query: 418 MGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALD 475
QD+DEC + + C GRCVNT GSF C+C GY G C D +EC
Sbjct: 343 FTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYT----GPRCETDVNECLSG 398
Query: 476 PRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCT 534
P C N TC + G + C C GFT + VD+DEC C + F CT
Sbjct: 399 P--CRNQATCLDRIGQFTCICMAGFTGTYCE--VDIDECQSSPCVNGGVCKDRVNGFSCT 454
Query: 535 CPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENAC 593
CP G++ G C+ D+DEC P C + Y C+C EG+ T ++
Sbjct: 455 CPSGFS----GSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRN----- 505
Query: 594 EDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
+++C D C G C++ SF C C G+ + + + R+ C
Sbjct: 506 --VDDCSP--DPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPC 551
Score = 208 bits (508), Expect = 6e-53
Identities = 197/643 (30%), Positives = 270/643 (41%), Gaps = 112/643 (17%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCEACPP-RGSP-AHTALCGEKP-GEYIN--PVTNE 64
C +V ++ C C G G C P SP AH A C P G ++ P +
Sbjct: 53 CQSSVVAGTARFSCRCPRGFR-GPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQ 111
Query: 65 TKP----IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+ +DEC + GTC +TP F+C C GY T LC + PC
Sbjct: 112 GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY----TGPLCEN-PAVPCAPSPC 166
Query: 121 RGMAQCVNLPG-AFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCEC 178
R C ++C C PG+ CE +VD+C R + G C + + +Y C+C
Sbjct: 167 RNGGTCRQSGDLTYDCACLPGF----EGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQC 222
Query: 179 KPGYTLRENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECR 237
P +T + DVDEC C N GTC N G + C C +G+ + +D +C
Sbjct: 223 PPEWT-GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNID--DCA 279
Query: 238 EGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
VC +G C + V SF C C G T G C D C + +PC D
Sbjct: 280 TA--VCFHGATCHDRVASFYCACPMGKT----GLLCHLDDAC--VSNPCHEDAICDTNPV 331
Query: 297 NGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRFDKTA 354
NG C+C G+ G C D DEC C G C N G ++C+C G+ T
Sbjct: 332 NGRAICTCPPGF--TGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY----TG 385
Query: 355 AVCVDERKELCYDEWEAGRC-HRARPL-QLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
C E +E +G C ++A L ++ + C C G G YCE
Sbjct: 386 PRC-----ETDVNECLSGPCRNQATCLDRIGQFTCICMAGFT-GTYCE------------ 427
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDAD 470
D+DEC+ P CV GG C + F C CP G+ G +C +D D
Sbjct: 428 ------------VDIDECQSSP--CVNGGVCKDRVNGFSCTCPSGF----SGSTCQLDVD 469
Query: 471 ECALDPRICGNGT-CSNTRGGYECQCSPGFTQGPDQTCVD--VDECAEGRASCTFRCHNT 527
ECA P C NG C + GYEC+C+ GF + T D VD+C+ RC +
Sbjct: 470 ECASTP--CRNGAKCVDQPDGYECRCAEGF----EGTLCDRNVDDCSPDPCH-HGRCVDG 522
Query: 528 AGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTS 584
SF C C GY G C +DEC +P C H C ++V Y+C+CP G +
Sbjct: 523 IASFSCACAPGYT----GTRCESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSGTTGVN 576
Query: 585 APQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
CE +I++C C+ GVC + + C C GF
Sbjct: 577 --------CEVNIDDCASNP--CTFGVCRDGINRYDCVCQPGF 609
Score = 197 bits (480), Expect = 2e-49
Identities = 193/668 (28%), Positives = 265/668 (39%), Gaps = 98/668 (14%)
Query: 20 KYLCCCSVGHAWGAPCEACPP--RGSPAHTALCGE---------KPGEYINPVTNETKPI 68
KYLC C G G CE +P +C + +PG + P+ N I
Sbjct: 563 KYLCRCPSGTT-GVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPG-FTGPLCNVE--I 618
Query: 69 DECDIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+EC P C + G+C D GF+C C G + LC P G+ C
Sbjct: 619 NECASSP--CGEGGSCVDGENGFRCLCPPG----SLPPLCLPPSHPCAHEPCSHGI--CY 670
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
+ PG F C C PG+ P + D C Q G C + + C C PG R+
Sbjct: 671 DAPGGFRCVCEPGWS-GPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQ- 728
Query: 188 VCRDVDECSRPRPVCRNGTCENLPGAY-LCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
C + C+ P P G CE+ PG +C C G++ GP DV+EC +G
Sbjct: 729 -CELLSPCT-PNPCEHGGRCESAPGQLPVCSCPQGWQ-GPRCQ-QDVDECAGPAPCGPHG 784
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C N GSF C C GYT G +C +D+++CD P+PC G SC + G + CSC
Sbjct: 785 ICTNLAGSFSCTCHGGYT----GPSCDQDINDCD--PNPCLNGG--SCQDGVGSFSCSCL 836
Query: 306 AGWKLVGRRCV-DRDECKELPYVCAGGECRNFNGGYVCECPAGW-----RFDK------- 352
G+ G RC D DEC P C G C + + C CP G+ D
Sbjct: 837 PGF--AGPRCARDVDECLSNP--CGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSS 892
Query: 353 --TAAVCVDERKE---LCYDEWEAGRC-HRARPLQLARPECCCSEGAAWGRYCERCPAPD 406
CVD LC + C H A P L+RP C G C A
Sbjct: 893 CFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPC-LSRP---CLHGGV-------CSAAH 941
Query: 407 SAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLS 465
F C P +D C +P C GGRCV T G++ C CP G+ +
Sbjct: 942 PG-FRCTCLESFTGPQCQTLVDWCSRQP--CQNGGRCVQT-GAY-CLCPPGWSGRLCDIR 996
Query: 466 CVDADECALD-----PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS 519
+ E A ++C G C + + C C G T + +VD C
Sbjct: 997 SLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQ--EVDPCLAQPCQ 1054
Query: 520 CTFRCHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPH--ACENVVGSYICKC 576
C G + C C GY +G +C D +DEC +P C H +C ++V Y+C C
Sbjct: 1055 HGGTCRGYMGGYMCECLPGY----NGDNCEDDVDECASQP--CQHGGSCIDLVARYLCSC 1108
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCI 636
P G + +E+ C + G C++ G F C C G+ D
Sbjct: 1109 PPGTLGVLC-EINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADIN 1167
Query: 637 DRRTGTCY 644
+ R+G C+
Sbjct: 1168 ECRSGACH 1175
Score = 192 bits (468), Expect = 4e-48
Identities = 181/597 (30%), Positives = 255/597 (42%), Gaps = 101/597 (16%)
Query: 75 PQLCKPG-TCHDTPTGFQ-CGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGA 132
P C+ G C P C C G++ +DVDEC+ G PC C NL G+
Sbjct: 737 PNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQ---QDVDECA-GPAPCGPHGICTNLAGS 792
Query: 133 FECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDV 192
F C C GY PS D+ D+++C + G C++ +GS+ C C PG+ RDV
Sbjct: 793 FSCTCHGGYT-GPSCDQ--DINDCDPNPCLNGGSCQDGVGSFSCSCLPGFA-GPRCARDV 848
Query: 193 DEC-SRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRN 250
DEC S P C GTC + ++ C C G+ G + D+ +C C NG C +
Sbjct: 849 DECLSNP---CGPGTCTDHVASFTCTCPPGY--GGFHCEQDLPDCSPSS--CFNGGTCVD 901
Query: 251 TVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
V SF C C PGYT G +C+ + D C L PC G C+ + G+ C+C +
Sbjct: 902 GVNSFSCLCRPGYT----GAHCQHEADPC--LSRPCLHGG--VCSAAHPGFRCTCLESF- 952
Query: 310 LVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCECPAGWR---FDKTAAVCVDERKEL 364
G +C D C P C GG C G Y C CP GW D + C + ++
Sbjct: 953 -TGPQCQTLVDWCSRQP--CQNGGRCVQ-TGAY-CLCPPGWSGRLCDIRSLPCREAAAQI 1007
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAE--------------F 410
+ + + + C C EG G +CE+ P A+ +
Sbjct: 1008 GVRLEQLCQAGGQCVDEDSSHYCVCPEGRT-GSHCEQEVDPCLAQPCQHGGTCRGYMGGY 1066
Query: 411 MRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VD 468
M C G N D+DEC +P C GG C++ + C CP G + G+ C ++
Sbjct: 1067 MCECLPGYNGDNCEDDVDECASQP--CQHGGSCIDLVARYLCSCPPGTL----GVLCEIN 1120
Query: 469 ADECA----LD--PRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEG--RAS 519
D+C LD PR NGTC + GG+ C C PG+T C D++EC G A+
Sbjct: 1121 EDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT---GLRCEADINECRSGACHAA 1177
Query: 520 CTFRC-HNTAGSFRCTCPYGYAVAADGVHCRDI-DECVQEPRVCPHA--CENVVG----- 570
T C + G FRC C G++ G C+ + C +P C H C G
Sbjct: 1178 HTRDCLQDPGGGFRCLCHAGFS----GPRCQTVLSPCESQP--CQHGGQCRPSPGPGGGL 1231
Query: 571 SYICKCPEGYRRTSAPQDSENACEDI-NECEEQEDLCSGGV-CINTDGSFLCDCDAG 625
++ C C + + P+ CE + C E + C GV C T C C G
Sbjct: 1232 TFTCHCAQPF---WGPR-----CERVARSCRELQ--CPVGVPCQQTPRGPRCACPPG 1278
Score = 176 bits (428), Expect = 3e-43
Identities = 189/663 (28%), Positives = 246/663 (37%), Gaps = 103/663 (15%)
Query: 236 CREGGMVCRNGRCRNTVG-SFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDG--NPS 292
C +G GRC C C PG+ G C+ D C PC G S
Sbjct: 3 CLDGSPCANGGRCTQLPSREAACLCPPGWV----GERCQLEDPCHS--GPCAGRGVCQSS 56
Query: 293 CTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECR-NFNGGYVCECPAGWRF 350
+ C C G++ G C D C P CA G C +G ++C CP G++
Sbjct: 57 VVAGTARFSCRCPRGFR--GPDCSLPDPCLSSP--CAHGARCSVGPDGRFLCSCPPGYQ- 111
Query: 351 DKTAAVCVDERK--ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSA 408
++ VDE + E C G C P C C G G CE P +
Sbjct: 112 GRSCRSDVDECRVGEPCR---HGGTCLNT-PGSF---RCQCPAGYT-GPLCENPAVPCAP 163
Query: 409 EFMRICQGGMGRPN--LTQDL--------DECRVRPDVCVGGRCVN----TDG--SFRCE 452
R GG R + LT D C V D C G RC+N DG ++ C+
Sbjct: 164 SPCR--NGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQ 221
Query: 453 CPDGYVLAPDGLSCV-DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDV 510
CP + G C D DEC L P C NG TC NT GG+ C C G+T + ++
Sbjct: 222 CPPEWT----GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTG--ESCSQNI 275
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN--V 568
D+CA CH+ SF C CP G G+ C D CV P C+ V
Sbjct: 276 DDCATAVCFHGATCHDRVASFYCACPMGKT----GLLCHLDDACVSNPCHEDAICDTNPV 331
Query: 569 VGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP 628
G IC CP G+ + QD + N CE G C+NT GSFLC C G+
Sbjct: 332 NGRAICTCPPGFTGGACDQDVDECSIGANPCEHL------GRCVNTQGSFLCQCGRGYTG 385
Query: 629 SEDGTD---CID---RRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTK 682
TD C+ R TC + C G V K
Sbjct: 386 PRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCK 445
Query: 683 AQ-----CCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXX 737
+ C C G + GS C+L +D C + TP
Sbjct: 446 DRVNGFSCTCPSGFS-GSTCQL--------DVDECAS---TPCRNGAKCVDQPDGYECRC 493
Query: 738 XXXXLDVFAD--VDECAAIP---GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPP 789
D VD+C+ P G C G F C C PGY G C + VDEC +P
Sbjct: 494 AEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGY--TGTRCESQVDECRSQPC 551
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCE 848
C + Y C C +G G NC ++D+C + T +C + Y+C C+
Sbjct: 552 RHGGKCLDLVDKYLCRCPSG----TTGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQ 606
Query: 849 DGY 851
G+
Sbjct: 607 PGF 609
Score = 130 bits (314), Expect = 2e-29
Identities = 158/516 (30%), Positives = 201/516 (38%), Gaps = 90/516 (17%)
Query: 21 YLCCCSVGHAWGAPC--EACPPRGSPA-HTALCGEK-PGEYINPVTNETKPIDECDIMPQ 76
+ C C G+ GA C EA P P H +C PG + + T P +C +
Sbjct: 906 FSCLCRPGYT-GAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGP--QCQTLVD 962
Query: 77 LCKPGTCHD----TPTGFQCGCDHGYEH---DNTSHLCRDVDECSWGRPP--CRGMAQCV 127
C C + TG C C G+ D S CR+ R C+ QCV
Sbjct: 963 WCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCV 1022
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD-CRNTIGSYRCECKPGYTLRE 186
+ + C CP G T S E ++VD C Q C HG CR +G Y CEC PGY +
Sbjct: 1023 DEDSSHYCVCPEGR--TGSHCE-QEVDPCLAQP-CQHGGTCRGYMGGYMCECLPGYN-GD 1077
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG----PNNDCVDVNECREGGMV 242
N DVDEC+ +P G+C +L YLC C G +DC G
Sbjct: 1078 NCEDDVDECA-SQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRC 1136
Query: 243 CRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSC-TNTNGGY 300
NG C + VG FRC C PGYT G C D++EC C C + GG+
Sbjct: 1137 LHNGTCVDLVGGFRCTCPPGYT----GLRCEADINECRS--GACHAAHTRDCLQDPGGGF 1190
Query: 301 ECSCGAGWKLVGRRC-VDRDECKELPYVCA-GGECR---NFNGG--YVCECPA---GWRF 350
C C AG+ G RC C+ P C GG+CR GG + C C G R
Sbjct: 1191 RCLCHAGFS--GPRCQTVLSPCESQP--CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRC 1246
Query: 351 DKTAAVCVDERKELCYDEWEAGRCHRARPLQLA--RPECCCSEGAAWGRYCERCPAPDSA 408
++ A C +EL +C P Q P C C G + G C P
Sbjct: 1247 ERVARSC----REL--------QCPVGVPCQQTPRGPRCACPPGLS-GPSCRSFPGSPP- 1292
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRC--VNTDGSFRCECPDGYVLAPDGLS 465
G N + C P C+ GG C FRC C G+ P +
Sbjct: 1293 ----------GASNAS-----CAAAP--CLHGGSCRPAPLAPFFRCACAQGWT-GPRCEA 1334
Query: 466 CVDADECALDPRICGNGTCSNTRGGYEC--QC-SPG 498
A E + +PR C C RG C +C SPG
Sbjct: 1335 PAAAPEVSEEPR-CPRAACQAKRGDQRCDRECNSPG 1369
Score = 125 bits (301), Expect = 8e-28
Identities = 163/564 (28%), Positives = 211/564 (37%), Gaps = 103/564 (18%)
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ 125
+ +DEC P C PGTC D F C C GY H +D+ +CS C
Sbjct: 846 RDVDECLSNP--CGPGTCTDHVASFTCTCPPGY---GGFHCEQDLPDCS--PSSCFNGGT 898
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGD-CRNTIGSYRCECKPGYT 183
CV+ +F C C PGY C+ + D C R C HG C +RC C +T
Sbjct: 899 CVDGVNSFSCLCRPGYTGA----HCQHEADPCLS-RPCLHGGVCSAAHPGFRCTCLESFT 953
Query: 184 LRENVCRD-VDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGG-- 240
+ C+ VD CSR +P G C GAY C C G+ +G D + CRE
Sbjct: 954 GPQ--CQTLVDWCSR-QPCQNGGRCVQT-GAY-CLCPPGW-SGRLCDIRSL-PCREAAAQ 1006
Query: 241 ------MVCR-NGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPS 292
+C+ G+C + S C C G T G +C ++VD C L PC G +
Sbjct: 1007 IGVRLEQLCQAGGQCVDEDSSHYCVCPEGRT----GSHCEQEVDPC--LAQPCQHGG--T 1058
Query: 293 CTNTNGGYECSCGAGWKLVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCECPAGWRF 350
C GGY C C G+ G C D DEC P C GG C + Y+C CP G
Sbjct: 1059 CRGYMGGYMCECLPGYN--GDNCEDDVDECASQP--CQHGGSCIDLVARYLCSCPPG--- 1111
Query: 351 DKTAAVCVDERKELCYD--EWEAG-RC-HRARPLQLA---RPEC--------C------C 389
T V + ++ C ++G RC H + L R C C C
Sbjct: 1112 --TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINEC 1169
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDG- 447
GA + C F +C G P L C +P C GG+C + G
Sbjct: 1170 RSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQP--CQHGGQCRPSPGP 1227
Query: 448 ----SFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
+F C C + G C + + C T G C C PG + GP
Sbjct: 1228 GGGLTFTCHCAQPFW----GPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLS-GP 1282
Query: 504 DQTCVDVDECAEGRASC---------TFRCHNTAGSFRCTCPYGYAVAADGVHCR---DI 551
ASC + R A FRC C G+ G C
Sbjct: 1283 SCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWT----GPRCEAPAAA 1338
Query: 552 DECVQEPRVCPH-ACENVVGSYIC 574
E +EPR CP AC+ G C
Sbjct: 1339 PEVSEEPR-CPRAACQAKRGDQRC 1361
Score = 64.1 bits (149), Expect = 2e-09
Identities = 87/334 (26%), Positives = 120/334 (35%), Gaps = 51/334 (15%)
Query: 72 DIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLP 130
D P+ GTC D GF+C C GY T C D++EC G C+ P
Sbjct: 1131 DSGPRCLHNGTCVDLVGGFRCTCPPGY----TGLRCEADINECRSGACHAAHTRDCLQDP 1186
Query: 131 GA-FECRCPPGYRLTPSLDECEDVDECGDQRICDHG-DCRNTIG-----SYRCEC-KPGY 182
G F C C G+ S C+ V + + C HG CR + G ++ C C +P +
Sbjct: 1187 GGGFRCLCHAGF----SGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFW 1242
Query: 183 TLR-ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF-----KAGPNNDCVDVNEC 236
R E V R E P V C+ P C C G ++ P + N
Sbjct: 1243 GPRCERVARSCRELQCPVGV----PCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNAS 1298
Query: 237 REGGMVCRNGRCRNT--VGSFRCECAPGYT------------LTADGRNCRDVDECDELP 282
G CR FRC CA G+T ++ + R R +
Sbjct: 1299 CAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGD 1358
Query: 283 HPCGRDGN-PSCTNTNGGYECSCGAGWK-LVGRRCVDRDECKELPYVCAGGECRNFNGGY 340
C R+ N P C G S G W+ +C C+ C N
Sbjct: 1359 QRCDRECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDN--- 1415
Query: 341 VCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC 374
+C AG R ++T C ++ C D + GRC
Sbjct: 1416 -FDCHAGGR-ERT---CNPVYEKYCADHFADGRC 1444
Score = 59.3 bits (137), Expect = 6e-08
Identities = 36/114 (31%), Positives = 52/114 (45%), Gaps = 14/114 (12%)
Query: 747 DVDECAAIP----GLCAP--GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
DV+EC + P C G+F C+C G+ G C D+DEC P +C +
Sbjct: 391 DVNECLSGPCRNQATCLDRIGQFTCICMAGF--TGTYCEVDIDECQSSPCVNGGVCKDRV 448
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+ C C +G+ G+ C+ DVDEC C + YEC C +G+E
Sbjct: 449 NGFSCTCPSGFS----GSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFE 498
Score = 58.4 bits (135), Expect = 1e-07
Identities = 40/97 (41%), Positives = 52/97 (53%), Gaps = 12/97 (12%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY--ELDED 815
GRF C C PGY+ G C +DVDEC V PC C NT GS+ C C GY L E+
Sbjct: 100 GRFLCSCPPGYQ--GRSCRSDVDECRV-GEPCRHGGTCLNTPGSFRCQCPAGYTGPLCEN 156
Query: 816 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
A C R+ TC+Q + + +Y+C+C G+E
Sbjct: 157 PAVPCAPSPC-RNGGTCRQ---SGDLTYDCACLPGFE 189
Score = 53.2 bits (122), Expect = 4e-06
Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 14/109 (12%)
Query: 756 GLCAPG--RFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY 810
G C G + C C P + G+ C DVDEC ++P C C NT G + C+C G+
Sbjct: 209 GTCVDGVNTYNCQCPPEW--TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW 266
Query: 811 ELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
G +C +++D+C C + S+ C+C G K G C
Sbjct: 267 ----TGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMG--KTGLLC 309
Score = 52.8 bits (121), Expect = 5e-06
Identities = 32/117 (27%), Positives = 48/117 (41%), Gaps = 15/117 (12%)
Query: 747 DVDECAAIP----GLCAPGR--FRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDG 800
+++ECA+ P G C G FRC+C PG P +C P +C++ G
Sbjct: 617 EINECASSPCGEGGSCVDGENGFRCLCPPGSLPP--LCLPPSHPCAHEPCSHGICYDAPG 674
Query: 801 SYDCLCRTGYELDEDGANCRDV---DECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
+ C+C G+ G C D CE CS+ + C+C G + R
Sbjct: 675 GFRCVCEPGW----SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGR 727
Score = 51.2 bits (117), Expect = 2e-05
Identities = 34/101 (33%), Positives = 45/101 (44%), Gaps = 15/101 (14%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSYD-CLCRTGYELDEDGANC 819
F C C PG + G C + C P PC+ C + G C C G++ G C
Sbjct: 716 FHCTCPPGVQ--GRQCELLSPCT--PNPCEHGGRCESAPGQLPVCSCPQGWQ----GPRC 767
Query: 820 R-DVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDAC 858
+ DVDEC IC+N GS+ C+C GY G +C
Sbjct: 768 QQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGY--TGPSC 806
Score = 45.6 bits (103), Expect = 8e-04
Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 12/103 (11%)
Query: 756 GLC--APGRFRCVCGPGYRPAGEVCADV---DECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
G+C APG FRCVC PG+ +G C+ D C +P C + + C C G
Sbjct: 667 GICYDAPGGFRCVCEPGW--SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGV 724
Query: 811 ELDEDGANCRDVDECERDTHTCQQICSNTEGSYE-CSCEDGYE 852
+ G C + C + C + G CSC G++
Sbjct: 725 Q----GRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQ 763
Score = 44.0 bits (99), Expect = 0.002
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 19/123 (15%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHN 797
DVDEC P C G CVC G+ GE C+ ++D+CA CH+
Sbjct: 234 DVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW--TGESCSQNIDDCATAVCFHGATCHD 291
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSN--TEGSYECSCEDGYEKRG 855
S+ C C G + G C D C + IC G C+C G+ G
Sbjct: 292 RVASFYCACPMG----KTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGF--TG 345
Query: 856 DAC 858
AC
Sbjct: 346 GAC 348
Score = 38.3 bits (85), Expect = 0.11
Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 11/95 (11%)
Query: 765 CVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNT----DGSYDCLCRTGYELDEDGANCR 820
C+C PG+ GE C D C P +C ++ + C C G+ G +C
Sbjct: 25 CLCPPGW--VGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFR----GPDCS 78
Query: 821 DVDECERDTHTCQQICS-NTEGSYECSCEDGYEKR 854
D C CS +G + CSC GY+ R
Sbjct: 79 LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGR 113
Score = 37.9 bits (84), Expect = 0.15
Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 13/78 (16%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDEC---AVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 816
G FRC C PGY G C AD++EC A + G + CLC G+ G
Sbjct: 1147 GGFRCTCPPGY--TGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGF----SG 1200
Query: 817 ANCRDV-DECERDTHTCQ 833
C+ V CE + CQ
Sbjct: 1201 PRCQTVLSPCE--SQPCQ 1216
>AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 256 bits (628), Expect = 2e-67
Identities = 241/847 (28%), Positives = 345/847 (40%), Gaps = 127/847 (14%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCV 127
DEC P L G C D FQC C G+ T HLC+ DVDEC+ PC+ A+C+
Sbjct: 492 DECASSPCLHN-GRCLDKINEFQCECPTGF----TGHLCQYDVDECA--STPCKNGAKCL 544
Query: 128 NLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
+ P + C C GY T CE D+DEC D C +G C++ + ++ C C+PGYT
Sbjct: 545 DGPNTYTCVCTEGYTGT----HCEVDIDEC-DPDPCHYGSCKDGVATFTCLCRPGYT-GH 598
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
+ +++ECS +P GTC++ AYLC C G GPN + +++++C C +G
Sbjct: 599 HCETNINECSS-QPCRHGGTCQDRDNAYLCFCLKG-TTGPNCE-INLDDCASSP--CDSG 653
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C + + + C C PGYT G C ++DEC +PC G +C + G+ C C
Sbjct: 654 TCLDKIDGYECACEPGYT----GSMCNINIDEC--AGNPCHNGG--TCEDGINGFTCRCP 705
Query: 306 AGWKLVGRRCVDR-DECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKEL 364
G+ C+ +EC P C G CR+ GY C+C GW + C ++
Sbjct: 706 EGYH--DPTCLSEVNECNSNP--CVHGACRDSLNGYKCDCDPGW----SGTNC-----DI 752
Query: 365 CYDEWEAGRCHRARPLQ--LARPECCCSEGAAWGRYCE----RC---PAPDSAEFMRICQ 415
+E E+ C + + C C EG + G C+ C P + +
Sbjct: 753 NNNECESNPCVNGGTCKDMTSGYVCTCREGFS-GPNCQTNINECASNPCLNQGTCIDDVA 811
Query: 416 GGMGRPNLTQDLDECRV-----RPDVCV-GGRCVNTDG--SFRCECPDGYVLAPDGLSC- 466
G L C V P C GG C ++ SF C CP G+ G +C
Sbjct: 812 GYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGW----QGQTCE 867
Query: 467 VDADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
VD +EC L P C +G +C NT GGY C C G++ +T D+D+C C
Sbjct: 868 VDINECVLSP--CRHGASCQNTHGGYRCHCQAGYSGRNCET--DIDDCRPNPCHNGGSCT 923
Query: 526 NTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
+ + C C G+ G C DI+EC +P C + V SY C CP G+
Sbjct: 924 DGINTAFCDCLPGFR----GTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGF---- 975
Query: 585 APQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFEPS---EDGTDCIDR-- 638
S CE+ N + E C +GG C++ SF C C GF S D +C +
Sbjct: 976 ----SGIHCEN-NTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPC 1030
Query: 639 -RTGTCYRSLVSGRCE-PEXXXXXXXXXXXXXXXXXXXXXXGHV--TKAQCCCTLGAAW- 693
GTC S RC P+ G T Q C + W
Sbjct: 1031 LHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWT 1090
Query: 694 GSECEL----CPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVD 749
G C++ C +D+ D+ VD
Sbjct: 1091 GLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDL---VD 1147
Query: 750 ECAAIP----GLCAP--GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSY 802
EC+ P C G + C C GY G C++ +DEC P C + +Y
Sbjct: 1148 ECSPSPCQNGATCTDYLGGYSCKCVAGYH--GVNCSEEIDECLSHPCQNGGTCLDLPNTY 1205
Query: 803 DCLCRTGYELDEDGANCR-DVDECERDTHTCQQ--------ICSNTEGSYECSCEDGYEK 853
C C G + G +C +VD+C + C + G Y C+C G+
Sbjct: 1206 KCSCPRGTQ----GVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV- 1260
Query: 854 RGDACVG 860
G+ C G
Sbjct: 1261 -GERCEG 1266
Score = 230 bits (563), Expect = 1e-59
Identities = 202/664 (30%), Positives = 281/664 (42%), Gaps = 108/664 (16%)
Query: 32 GAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCK-PGTCHDTPTGF 90
G+ C+ P G A+C P Y P ++ +DEC + C+ G C +T F
Sbjct: 384 GSNCDTNPVNGK----AIC-TCPSGYTGPACSQD--VDECSLGANPCEHAGKCINTLGSF 436
Query: 91 QCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDE 149
+C C GY T C DV+EC PC+ A C++ G F+C C PGY
Sbjct: 437 ECQCLQGY----TGPRCEIDVNECVSN--PCQNDATCLDQIGEFQCICMPGYEGV----H 486
Query: 150 CE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGT- 206
CE + DEC +G C + I ++CEC G+T ++C+ DVDEC+ C+NG
Sbjct: 487 CEVNTDECASSPCLHNGRCLDKINEFQCECPTGFT--GHLCQYDVDECASTP--CKNGAK 542
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLT 266
C + P Y C C +G+ G + + VD++EC C G C++ V +F C C PGYT
Sbjct: 543 CLDGPNTYTCVCTEGY-TGTHCE-VDIDECDPDP--CHYGSCKDGVATFTCLCRPGYT-- 596
Query: 267 ADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKEL 324
G +C +++EC PC G +C + + Y C C G G C ++ D+C
Sbjct: 597 --GHHCETNINECSS--QPCRHGG--TCQDRDNAYLCFCLKG--TTGPNCEINLDDCASS 648
Query: 325 PYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE-------RKELCYDEWEAGRCHRA 377
P C G C + GY C C G+ + +DE C D C
Sbjct: 649 P--CDSGTCLDKIDGYECACEPGYT-GSMCNINIDECAGNPCHNGGTCEDGINGFTCRC- 704
Query: 378 RPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRI-CQGGMGRPNLTQDLDECRVRPDV 436
P P C C DS + C G N + +EC P
Sbjct: 705 -PEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNP-- 761
Query: 437 CV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQ 494
CV GG C + + C C +G+ G +C + +ECA +P + GTC + GY+C
Sbjct: 762 CVNGGTCKDMTSGYVCTCREGF----SGPNCQTNINECASNPCL-NQGTCIDDVAGYKCN 816
Query: 495 CSPGFTQGPDQTC-VDVDECAEGRASCTFRCHNTAG--SFRCTCPYGYAVAADGVHCR-D 550
C +T TC V + CA C + SF C CP G+ G C D
Sbjct: 817 CLLPYTGA---TCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGW----QGQTCEVD 869
Query: 551 IDECVQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLC- 606
I+ECV P C H +C+N G Y C C GY S CE DI++C C
Sbjct: 870 INECVLSP--CRHGASCQNTHGGYRCHCQAGY--------SGRNCETDIDDCRPNP--CH 917
Query: 607 SGGVCINTDGSFLCDCDAGF--------------EPSEDG---TDCIDRRTGTCYRSLVS 649
+GG C + + CDC GF +P +G TDC+D T TC
Sbjct: 918 NGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSG 977
Query: 650 GRCE 653
CE
Sbjct: 978 IHCE 981
Score = 225 bits (551), Expect = 4e-58
Identities = 232/852 (27%), Positives = 325/852 (38%), Gaps = 134/852 (15%)
Query: 32 GAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCK-PGTCHDTP--- 87
G CEA G+ A +CG G ++ P + P C P CK GTCH
Sbjct: 34 GGKCEAA--NGTEA--CVCG---GAFVGPRCQDPNP---CLSTP--CKNAGTCHVVDRRG 81
Query: 88 -TGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLP-GAFECRCPPGYRLTP 145
+ C C G+ + LC + + PCR C L ++CRCPPG+
Sbjct: 82 VADYACSCALGF----SGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGW---- 133
Query: 146 SLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRN 204
S C+ D C + G C SY C C P + CR DV+EC + +CR+
Sbjct: 134 SGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSF--HGPTCRQDVNECGQKPGLCRH 191
Query: 205 G-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVG-SFRCECAP 261
G TC N G+Y C C GPN + V C C+NG CR T + C C P
Sbjct: 192 GGTCHNEVGSYRCVCR-ATHTGPNCERPYV-PCSPSP--CQNGGTCRPTGDVTHECACLP 247
Query: 262 GYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV-DRD 319
G+T G+NC + +D+C + C G +C + Y C C W G+ C D D
Sbjct: 248 GFT----GQNCEENIDDCPG--NNCKNGG--ACVDGVNTYNCRCPPEW--TGQYCTEDVD 297
Query: 320 ECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRAR 378
EC+ +P C GG C N +GGY C C GW + + D C+ CH
Sbjct: 298 ECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACF---HGATCHD-- 352
Query: 379 PLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV 438
++A C C G G C + A C G C P V
Sbjct: 353 --RVASFYCECPHGRT-GLLCHL----NDACISNPCNEG----------SNCDTNP---V 392
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGN-GTCSNTRGGYECQCS 496
G+ + C CP GY G +C D DEC+L C + G C NT G +ECQC
Sbjct: 393 NGKAI-------CTCPSGYT----GPACSQDVDECSLGANPCEHAGKCINTLGSFECQCL 441
Query: 497 PGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECV 555
G+T GP + +DV+EC C + G F+C C GY +GVHC + DEC
Sbjct: 442 QGYT-GP-RCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGY----EGVHCEVNTDECA 495
Query: 556 QEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGG---VCI 612
P + C + + + C+CP G+ D + C+ G C+
Sbjct: 496 SSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECAS--TPCKNGAKCLDGPNTYTCV 553
Query: 613 NTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXX 672
T+G C+ + D C G+C + + C
Sbjct: 554 CTEGYTGTHCEVDIDEC-DPDPC---HYGSCKDGVATFTCLCRPGYTGHHCETNINECSS 609
Query: 673 XXXXXGHVTK----AQCCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXX 728
G + A C L G CE+ LD C +
Sbjct: 610 QPCRHGGTCQDRDNAYLCFCLKGTTGPNCEI--------NLDDCASSPCDSGTCLDKIDG 661
Query: 729 XXXXXXXXXXXXXLDVFADVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVCADVD 782
++ ++DECA P G C G F C C GY ++V+
Sbjct: 662 YECACEPGYTGSMCNI--NIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDP-TCLSEVN 718
Query: 783 ECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNT 839
EC PC C ++ Y C C G+ G NC D++ E +++ C C +
Sbjct: 719 EC--NSNPCVHGACRDSLNGYKCDCDPGWS----GTNC-DINNNECESNPCVNGGTCKDM 771
Query: 840 EGSYECSCEDGY 851
Y C+C +G+
Sbjct: 772 TSGYVCTCREGF 783
Score = 213 bits (521), Expect = 2e-54
Identities = 186/609 (30%), Positives = 259/609 (42%), Gaps = 98/609 (16%)
Query: 69 DECDIMPQLCKPGT-CHDTPTGFQ--CGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMA 124
D C P C G+ C P + C C GY T C +DVDECS G PC
Sbjct: 374 DACISNP--CNEGSNCDTNPVNGKAICTCPSGY----TGPACSQDVDECSLGANPCEHAG 427
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYT 183
+C+N G+FEC+C GY + CE DV+EC + C + IG ++C C PGY
Sbjct: 428 KCINTLGSFECQCLQGY----TGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGY- 482
Query: 184 LRENV-CR-DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGG 240
E V C + DEC+ P NG C + + C C GF + C DV+EC
Sbjct: 483 --EGVHCEVNTDECA-SSPCLHNGRCLDKINEFQCECPTGF---TGHLCQYDVDEC--AS 534
Query: 241 MVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNG 298
C+NG +C + ++ C C GYT G +C D+DECD P PC SC +
Sbjct: 535 TPCKNGAKCLDGPNTYTCVCTEGYT----GTHCEVDIDECD--PDPCHYG---SCKDGVA 585
Query: 299 GYECSCGAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAV 356
+ C C G+ G C + +EC P C GG C++ + Y+C C G T
Sbjct: 586 TFTCLCRPGY--TGHHCETNINECSSQP--CRHGGTCQDRDNAYLCFCLKG----TTGPN 637
Query: 357 CVDERKELCYDEWEAGRCHRARPL-QLARPECCCSEGAAWGRYC----ERC---PAPDSA 408
C E+ D+ + C L ++ EC C G G C + C P +
Sbjct: 638 C-----EINLDDCASSPCDSGTCLDKIDGYECACEPGYT-GSMCNINIDECAGNPCHNGG 691
Query: 409 E-------FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAP 461
F C G P +++EC P CV G C ++ ++C+C G+
Sbjct: 692 TCEDGINGFTCRCPEGYHDPTCLSEVNECNSNP--CVHGACRDSLNGYKCDCDPGW---- 745
Query: 462 DGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRAS 519
G +C ++ +EC +P + G GTC + GY C C GF+ GP+ QT +++ECA
Sbjct: 746 SGTNCDINNNECESNPCVNG-GTCKDMTSGYVCTCREGFS-GPNCQT--NINECASNPCL 801
Query: 520 CTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI-DECVQEPRVCPHACENV--VGSYICKC 576
C + ++C C Y G C + C P C S+ C C
Sbjct: 802 NQGTCIDDVAGYKCNCLLPYT----GATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVC 857
Query: 577 PEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
P G++ CE DINEC G C NT G + C C AG+ TD
Sbjct: 858 PTGWQ--------GQTCEVDINEC-VLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDI 908
Query: 636 IDRRTGTCY 644
D R C+
Sbjct: 909 DDCRPNPCH 917
Score = 200 bits (489), Expect = 1e-50
Identities = 188/642 (29%), Positives = 258/642 (40%), Gaps = 103/642 (16%)
Query: 60 PVTNETKPIDECDIMPQLCKPG-TCHDTPT--GFQCGCDHGYEHDNTSHLCR-DVDECSW 115
P T T + P C+ G C + F C C G++ C D++EC
Sbjct: 820 PYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQ----GQTCEVDINECVL 875
Query: 116 GRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSY 174
PCR A C N G + C C GY S CE D+D+C + G C + I +
Sbjct: 876 S--PCRHGASCQNTHGGYRCHCQAGY----SGRNCETDIDDCRPNPCHNGGSCTDGINTA 929
Query: 175 RCECKPGYTLRENVCR-DVDECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVD 232
C+C PG+ R C D++EC+ CRNG C + +Y C C GF + +
Sbjct: 930 FCDCLPGF--RGTFCEEDINECASDP--CRNGANCTDCVDSYTCTCPAGFSGIHCEN--N 983
Query: 233 VNECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGN 290
+C E C NG C + + SF C C PG+T G C+ DV+ECD PC G
Sbjct: 984 TPDCTESS--CFNGGTCVDGINSFTCLCPPGFT----GSYCQHDVNECDS--QPCLHGG- 1034
Query: 291 PSCTNTNGGYECSCGAGWKLVGRRCVDRDE-CKELPYVCA-GGECRNFNGGYVCECPAGW 348
+C + G Y C+C G+ G C + C P C GG+C + Y CECP+GW
Sbjct: 1035 -TCQDGCGSYRCTCPQGY--TGPNCQNLVHWCDSSP--CKNGGKCWQTHTQYRCECPSGW 1089
Query: 349 R---FDKTAAVCVDERKELCYDEWEAGRC-HRARPLQLARPECCCSEGAAWGRYCE---- 400
D + C + D A C H + C + G YCE
Sbjct: 1090 TGLYCDVPSVSCEVAAQRQGVD--VARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVD 1147
Query: 401 RC-PAPDS---------AEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSF 449
C P+P + C G N ++++DEC P C GG C++ ++
Sbjct: 1148 ECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHP--CQNGGTCLDLPNTY 1205
Query: 450 RCECPDGYVLAPDGLSC-VDADEC-------ALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
+C CP G G+ C ++ D+C + P+ NGTC + GGY C C PGF
Sbjct: 1206 KCSCPRG----TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV- 1260
Query: 502 GPDQTCV-DVDECAEG--RASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQE 557
+ C DV+EC A T C F C C G+ G C I+ C +
Sbjct: 1261 --GERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHT----GRRCESVINGCKGK 1314
Query: 558 PRVCPHAC---ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINT 614
P C N +ICKCP G+ + D+ C + C +GG CI+
Sbjct: 1315 PCKNGGTCAVASNTARGFICKCPAGFEGATCENDA-RTCGSL-RC------LNGGTCISG 1366
Query: 615 DGSFLCDCDAGFEPSEDGTDCIDRRTG--TCYRSLVSGRCEP 654
S C C F E G CY G CEP
Sbjct: 1367 PRSPTCLCLGPFTGPECQFPASSPCLGGNPCYN---QGTCEP 1405
Score = 195 bits (475), Expect = 6e-49
Identities = 186/662 (28%), Positives = 270/662 (40%), Gaps = 117/662 (17%)
Query: 19 TKYLCCCSVGHAWGAPCEACPPRGS----------PAHTALCGEKPGEYINPVTNETKPI 68
T+Y C C G + G C+ P S P + P + P + +
Sbjct: 123 TEYKCRCPPGWS-GKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQD--V 179
Query: 69 DECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+EC P LC+ G TCH+ ++C C + N R CS PC+ C
Sbjct: 180 NECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCE---RPYVPCS--PSPCQNGGTCR 234
Query: 128 NLPGA-FECRCPPGYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
EC C PG+ + CE+ +D+C + G C + + +Y C C P +T
Sbjct: 235 PTGDVTHECACLPGF----TGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWT-G 289
Query: 186 ENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVD-VNECREGGMVC 243
+ DVDEC C+N GTC N G Y C C +G+ DC + +++C C
Sbjct: 290 QYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW---TGEDCSENIDDC--ASAAC 344
Query: 244 RNG-RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC 302
+G C + V SF CEC G T G C D C + +PC N NG C
Sbjct: 345 FHGATCHDRVASFYCECPHGRT----GLLCHLNDAC--ISNPCNEGSNCDTNPVNGKAIC 398
Query: 303 SCGAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
+C +G+ G C D DEC C G+C N G + C+C G+ T C
Sbjct: 399 TCPSGY--TGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY----TGPRC--- 449
Query: 361 RKELCYDEWEAGRCHRARPL--QLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
E+ +E + C Q+ +C C G G +CE
Sbjct: 450 --EIDVNECVSNPCQNDATCLDQIGEFQCICMPGYE-GVHCE------------------ 488
Query: 419 GRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPR 477
+ DEC P C+ GRC++ F+CECP G+ L D DECA P
Sbjct: 489 ------VNTDECASSP--CLHNGRCLDKINEFQCECPTGFT---GHLCQYDVDECASTP- 536
Query: 478 ICGNGT-CSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRCTC 535
C NG C + Y C C+ G+T + VD+DEC C + C + +F C C
Sbjct: 537 -CKNGAKCLDGPNTYTCVCTEGYTGTHCE--VDIDECDPD--PCHYGSCKDGVATFTCLC 591
Query: 536 PYGYAVAADGVHCR-DIDECVQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENA 592
GY G HC +I+EC +P C H C++ +Y+C C +G T+ P
Sbjct: 592 RPGYT----GHHCETNINECSSQP--CRHGGTCQDRDNAYLCFCLKG---TTGPN----- 637
Query: 593 CE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGR 651
CE ++++C C G C++ + C C+ G+ S + + C+ G
Sbjct: 638 CEINLDDCASSP--CDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHN---GGT 692
Query: 652 CE 653
CE
Sbjct: 693 CE 694
Score = 185 bits (451), Expect = 5e-46
Identities = 155/463 (33%), Positives = 190/463 (41%), Gaps = 73/463 (15%)
Query: 195 CSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRC---- 248
CS+P C NG CE G C C F GP C D N C C+N G C
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAF-VGPR--CQDPNPCLS--TPCKNAGTCHVVD 78
Query: 249 RNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
R V + C CA G++ G C + L +PC R+G T Y+C C GW
Sbjct: 79 RRGVADYACSCALGFS----GPLCLTPLDNACLTNPC-RNGGTCDLLTLTEYKCRCPPGW 133
Query: 309 KLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDE---RKEL 364
G+ C D C P CA GG+C F Y+C CP + T V+E + L
Sbjct: 134 S--GKSCQQADPCASNP--CANGGQCLPFEASYICHCPPSFH-GPTCRQDVNECGQKPGL 188
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQ-GGMGRP-- 421
C G CH ++ C C G CER P S CQ GG RP
Sbjct: 189 CR---HGGTCHN----EVGSYRCVC-RATHTGPNCERPYVPCSPS---PCQNGGTCRPTG 237
Query: 422 NLTQDL--------DECRVRPDVCVGGRCVN----TDG--SFRCECPDGYVLAPDGLSCV 467
++T + C D C G C N DG ++ C CP + G C
Sbjct: 238 DVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWT----GQYCT 293
Query: 468 -DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
D DEC L P C NG TC NT GGY C C G+T G D ++D+CA CH
Sbjct: 294 EDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWT-GED-CSENIDDCASAACFHGATCH 351
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN--VVGSYICKCPEGYRRT 583
+ SF C CP+G G+ C D C+ P C+ V G IC CP GY
Sbjct: 352 DRVASFYCECPHG----RTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGP 407
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
+ QD + N CE G CINT GSF C C G+
Sbjct: 408 ACSQDVDECSLGANPCEH------AGKCINTLGSFECQCLQGY 444
Score = 147 bits (355), Expect = 2e-34
Identities = 169/582 (29%), Positives = 226/582 (38%), Gaps = 93/582 (15%)
Query: 21 YLCCCSVGHAWGAPCEA----CPPR-----GSPA---HTALCGEKPGEYINPVTNETKPI 68
Y C C G++ G CE C P GS +TA C PG + E I
Sbjct: 891 YRCHCQAGYS-GRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPG-FRGTFCEED--I 946
Query: 69 DECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+EC P C+ G C D + C C G+ + + D E S C CV
Sbjct: 947 NECASDP--CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESS-----CFNGGTCV 999
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
+ +F C CPPG+ T S + DV+EC Q G C++ GSYRC C GYT
Sbjct: 1000 DGINSFTCLCPPGF--TGSYCQ-HDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPN- 1055
Query: 188 VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA----GPNNDCVDVNECREGGMVC 243
C+++ P G C Y C C G+ P+ C +V R+G V
Sbjct: 1056 -CQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSC-EVAAQRQGVDVA 1113
Query: 244 R----NGRCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNG 298
R G C + + C C GYT G C D VDEC P PC +CT+ G
Sbjct: 1114 RLCQHGGLCVDAGNTHHCRCQAGYT----GSYCEDLVDECS--PSPC--QNGATCTDYLG 1165
Query: 299 GYECSCGAGWKLVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAV 356
GY C C AG+ G C + DEC L + C GG C + Y C CP G + +
Sbjct: 1166 GYSCKCVAGYH--GVNCSEEIDEC--LSHPCQNGGTCLDLPNTYKCSCPRGTQ-GVHCEI 1220
Query: 357 CVDERKELCYDEWEAGRCHRARPL--QLARPECCCSEGAAWGRYCE---------RCPAP 405
VD+ + +C Q+ C C G G CE C A
Sbjct: 1221 NVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV-GERCEGDVNECLSNPCDAR 1279
Query: 406 DSA-------EFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCV---NTDGSFRCECP 454
+ +F C+ G ++ C+ +P C GG C NT F C+CP
Sbjct: 1280 GTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKP--CKNGGTCAVASNTARGFICKCP 1337
Query: 455 DGYVLAPDGLSCV-DADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDEC 513
G+ +G +C DA C R GTC + C C FT GP+ C
Sbjct: 1338 AGF----EGATCENDARTCG-SLRCLNGGTCISGPRSPTCLCLGPFT-GPECQFPASSPC 1391
Query: 514 AEGRASCT-FRCHNTAGS--FRCTCPYGYAVAADGVHCRDID 552
G C T+ S +RC CP + +G+ C +D
Sbjct: 1392 LGGNPCYNQGTCEPTSESPFYRCLCPAKF----NGLLCHILD 1429
Score = 66.5 bits (155), Expect = 4e-10
Identities = 72/263 (27%), Positives = 96/263 (36%), Gaps = 35/263 (13%)
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
P+D P+ GTC D G+ C C G+ + DV+EC RG C
Sbjct: 1228 PVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE---GDVNECLSNPCDARGTQNC 1284
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDV-DECGDQRICDHGDC---RNTIGSYRCECKPGY 182
V F C C G+ + CE V + C + + G C NT + C+C G+
Sbjct: 1285 VQRVNDFHCECRAGH----TGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGF 1340
Query: 183 TLRENVC-RDVDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGG 240
C D C R C N GTC + P + C C F GP + C G
Sbjct: 1341 --EGATCENDARTCGSLR--CLNGGTCISGPRSPTCLCLGPF-TGPECQFPASSPCLGGN 1395
Query: 241 MVCRNGRCRNTVGS--FRCECAPGYT--------LTADGRNCRD-----VDECDELPHPC 285
G C T S +RC C + + G RD ++E ELP C
Sbjct: 1396 PCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPE-C 1454
Query: 286 GRD-GNPSCTNTNGGYECSCGAG 307
D GN C+ + C G
Sbjct: 1455 QEDAGNKVCSLQCNNHACGWDGG 1477
Score = 64.9 bits (151), Expect = 1e-09
Identities = 36/96 (37%), Positives = 48/96 (50%), Gaps = 10/96 (10%)
Query: 761 GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDEDGA 817
G+ C C GY G C+ DVDEC++ PC+ C NT GS++C C GY G
Sbjct: 394 GKAICTCPSGY--TGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYT----GP 447
Query: 818 NCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
C DV+EC + C + G ++C C GYE
Sbjct: 448 RCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYE 483
Score = 50.4 bits (115), Expect = 3e-05
Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 15/110 (13%)
Query: 756 GLCAPG---RFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYE 811
G C P C C PG+ G+ C + +D+C C + +Y+C C +
Sbjct: 231 GTCRPTGDVTHECACLPGF--TGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWT 288
Query: 812 LDEDGANC-RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
G C DVDEC+ + CQ C NT G Y C C +G+ G+ C
Sbjct: 289 ----GQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW--TGEDC 332
Score = 46.4 bits (105), Expect = 4e-04
Identities = 34/102 (33%), Positives = 46/102 (45%), Gaps = 19/102 (18%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCD----QLCHNTDGSYDCLCRTGYELDED 815
G + C C PG+ GE C DV+EC P CD Q C + C CR G+
Sbjct: 1249 GGYSCTCPPGF--VGERCEGDVNECLSNP--CDARGTQNCVQRVNDFHCECRAGHT---- 1300
Query: 816 GANCRDV-DECE----RDTHTCQQICSNTEGSYECSCEDGYE 852
G C V + C+ ++ TC + SNT + C C G+E
Sbjct: 1301 GRRCESVINGCKGKPCKNGGTCA-VASNTARGFICKCPAGFE 1341
Score = 45.6 bits (103), Expect = 8e-04
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 19/123 (15%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHN 797
DVDEC +P C G + CVC G+ GE C++ +D+CA CH+
Sbjct: 295 DVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW--TGEDCSENIDDCASAACFHGATCHD 352
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSN--TEGSYECSCEDGYEKRG 855
S+ C C G G C D C + C G C+C GY G
Sbjct: 353 RVASFYCECPHG----RTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGY--TG 406
Query: 856 DAC 858
AC
Sbjct: 407 PAC 409
Score = 31.9 bits (69), Expect = 10.0
Identities = 26/99 (26%), Positives = 36/99 (36%), Gaps = 11/99 (11%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHN-TDGSYDCLCRTGYELDEDGANC 819
+ C C G+ +G +C + A PC C T Y C C G+ G +C
Sbjct: 85 YACSCALGF--SGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWS----GKSC 138
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
+ D C + C E SY C C + G C
Sbjct: 139 QQADPCASNPCANGGQCLPFEASYICHCPPSF--HGPTC 175
>AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 256 bits (628), Expect = 2e-67
Identities = 241/847 (28%), Positives = 345/847 (40%), Gaps = 127/847 (14%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCV 127
DEC P L G C D FQC C G+ T HLC+ DVDEC+ PC+ A+C+
Sbjct: 492 DECASSPCLHN-GRCLDKINEFQCECPTGF----TGHLCQYDVDECA--STPCKNGAKCL 544
Query: 128 NLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
+ P + C C GY T CE D+DEC D C +G C++ + ++ C C+PGYT
Sbjct: 545 DGPNTYTCVCTEGYTGT----HCEVDIDEC-DPDPCHYGSCKDGVATFTCLCRPGYT-GH 598
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
+ +++ECS +P GTC++ AYLC C G GPN + +++++C C +G
Sbjct: 599 HCETNINECSS-QPCRHGGTCQDRDNAYLCFCLKG-TTGPNCE-INLDDCASSP--CDSG 653
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C + + + C C PGYT G C ++DEC +PC G +C + G+ C C
Sbjct: 654 TCLDKIDGYECACEPGYT----GSMCNINIDEC--AGNPCHNGG--TCEDGINGFTCRCP 705
Query: 306 AGWKLVGRRCVDR-DECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKEL 364
G+ C+ +EC P C G CR+ GY C+C GW + C ++
Sbjct: 706 EGYH--DPTCLSEVNECNSNP--CVHGACRDSLNGYKCDCDPGW----SGTNC-----DI 752
Query: 365 CYDEWEAGRCHRARPLQ--LARPECCCSEGAAWGRYCE----RC---PAPDSAEFMRICQ 415
+E E+ C + + C C EG + G C+ C P + +
Sbjct: 753 NNNECESNPCVNGGTCKDMTSGYVCTCREGFS-GPNCQTNINECASNPCLNQGTCIDDVA 811
Query: 416 GGMGRPNLTQDLDECRV-----RPDVCV-GGRCVNTDG--SFRCECPDGYVLAPDGLSC- 466
G L C V P C GG C ++ SF C CP G+ G +C
Sbjct: 812 GYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGW----QGQTCE 867
Query: 467 VDADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
VD +EC L P C +G +C NT GGY C C G++ +T D+D+C C
Sbjct: 868 VDINECVLSP--CRHGASCQNTHGGYRCHCQAGYSGRNCET--DIDDCRPNPCHNGGSCT 923
Query: 526 NTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
+ + C C G+ G C DI+EC +P C + V SY C CP G+
Sbjct: 924 DGINTAFCDCLPGFR----GTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGF---- 975
Query: 585 APQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFEPS---EDGTDCIDR-- 638
S CE+ N + E C +GG C++ SF C C GF S D +C +
Sbjct: 976 ----SGIHCEN-NTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPC 1030
Query: 639 -RTGTCYRSLVSGRCE-PEXXXXXXXXXXXXXXXXXXXXXXGHV--TKAQCCCTLGAAW- 693
GTC S RC P+ G T Q C + W
Sbjct: 1031 LHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWT 1090
Query: 694 GSECEL----CPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVD 749
G C++ C +D+ D+ VD
Sbjct: 1091 GLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDL---VD 1147
Query: 750 ECAAIP----GLCAP--GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSY 802
EC+ P C G + C C GY G C++ +DEC P C + +Y
Sbjct: 1148 ECSPSPCQNGATCTDYLGGYSCKCVAGYH--GVNCSEEIDECLSHPCQNGGTCLDLPNTY 1205
Query: 803 DCLCRTGYELDEDGANCR-DVDECERDTHTCQQ--------ICSNTEGSYECSCEDGYEK 853
C C G + G +C +VD+C + C + G Y C+C G+
Sbjct: 1206 KCSCPRGTQ----GVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV- 1260
Query: 854 RGDACVG 860
G+ C G
Sbjct: 1261 -GERCEG 1266
Score = 230 bits (563), Expect = 1e-59
Identities = 202/664 (30%), Positives = 281/664 (42%), Gaps = 108/664 (16%)
Query: 32 GAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCK-PGTCHDTPTGF 90
G+ C+ P G A+C P Y P ++ +DEC + C+ G C +T F
Sbjct: 384 GSNCDTNPVNGK----AIC-TCPSGYTGPACSQD--VDECSLGANPCEHAGKCINTLGSF 436
Query: 91 QCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDE 149
+C C GY T C DV+EC PC+ A C++ G F+C C PGY
Sbjct: 437 ECQCLQGY----TGPRCEIDVNECVSN--PCQNDATCLDQIGEFQCICMPGYEGV----H 486
Query: 150 CE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGT- 206
CE + DEC +G C + I ++CEC G+T ++C+ DVDEC+ C+NG
Sbjct: 487 CEVNTDECASSPCLHNGRCLDKINEFQCECPTGFT--GHLCQYDVDECASTP--CKNGAK 542
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLT 266
C + P Y C C +G+ G + + VD++EC C G C++ V +F C C PGYT
Sbjct: 543 CLDGPNTYTCVCTEGY-TGTHCE-VDIDECDPDP--CHYGSCKDGVATFTCLCRPGYT-- 596
Query: 267 ADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKEL 324
G +C +++EC PC G +C + + Y C C G G C ++ D+C
Sbjct: 597 --GHHCETNINECSS--QPCRHGG--TCQDRDNAYLCFCLKG--TTGPNCEINLDDCASS 648
Query: 325 PYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE-------RKELCYDEWEAGRCHRA 377
P C G C + GY C C G+ + +DE C D C
Sbjct: 649 P--CDSGTCLDKIDGYECACEPGYT-GSMCNINIDECAGNPCHNGGTCEDGINGFTCRC- 704
Query: 378 RPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRI-CQGGMGRPNLTQDLDECRVRPDV 436
P P C C DS + C G N + +EC P
Sbjct: 705 -PEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNP-- 761
Query: 437 CV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQ 494
CV GG C + + C C +G+ G +C + +ECA +P + GTC + GY+C
Sbjct: 762 CVNGGTCKDMTSGYVCTCREGF----SGPNCQTNINECASNPCL-NQGTCIDDVAGYKCN 816
Query: 495 CSPGFTQGPDQTC-VDVDECAEGRASCTFRCHNTAG--SFRCTCPYGYAVAADGVHCR-D 550
C +T TC V + CA C + SF C CP G+ G C D
Sbjct: 817 CLLPYTGA---TCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGW----QGQTCEVD 869
Query: 551 IDECVQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLC- 606
I+ECV P C H +C+N G Y C C GY S CE DI++C C
Sbjct: 870 INECVLSP--CRHGASCQNTHGGYRCHCQAGY--------SGRNCETDIDDCRPNP--CH 917
Query: 607 SGGVCINTDGSFLCDCDAGF--------------EPSEDG---TDCIDRRTGTCYRSLVS 649
+GG C + + CDC GF +P +G TDC+D T TC
Sbjct: 918 NGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSG 977
Query: 650 GRCE 653
CE
Sbjct: 978 IHCE 981
Score = 225 bits (551), Expect = 4e-58
Identities = 232/852 (27%), Positives = 325/852 (38%), Gaps = 134/852 (15%)
Query: 32 GAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCK-PGTCHDTP--- 87
G CEA G+ A +CG G ++ P + P C P CK GTCH
Sbjct: 34 GGKCEAA--NGTEA--CVCG---GAFVGPRCQDPNP---CLSTP--CKNAGTCHVVDRRG 81
Query: 88 -TGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLP-GAFECRCPPGYRLTP 145
+ C C G+ + LC + + PCR C L ++CRCPPG+
Sbjct: 82 VADYACSCALGF----SGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGW---- 133
Query: 146 SLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRN 204
S C+ D C + G C SY C C P + CR DV+EC + +CR+
Sbjct: 134 SGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSF--HGPTCRQDVNECGQKPGLCRH 191
Query: 205 G-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVG-SFRCECAP 261
G TC N G+Y C C GPN + V C C+NG CR T + C C P
Sbjct: 192 GGTCHNEVGSYRCVCR-ATHTGPNCERPYV-PCSPSP--CQNGGTCRPTGDVTHECACLP 247
Query: 262 GYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV-DRD 319
G+T G+NC + +D+C + C G +C + Y C C W G+ C D D
Sbjct: 248 GFT----GQNCEENIDDCPG--NNCKNGG--ACVDGVNTYNCRCPPEW--TGQYCTEDVD 297
Query: 320 ECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRAR 378
EC+ +P C GG C N +GGY C C GW + + D C+ CH
Sbjct: 298 ECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACF---HGATCHD-- 352
Query: 379 PLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV 438
++A C C G G C + A C G C P V
Sbjct: 353 --RVASFYCECPHGRT-GLLCHL----NDACISNPCNEG----------SNCDTNP---V 392
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGN-GTCSNTRGGYECQCS 496
G+ + C CP GY G +C D DEC+L C + G C NT G +ECQC
Sbjct: 393 NGKAI-------CTCPSGYT----GPACSQDVDECSLGANPCEHAGKCINTLGSFECQCL 441
Query: 497 PGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECV 555
G+T GP + +DV+EC C + G F+C C GY +GVHC + DEC
Sbjct: 442 QGYT-GP-RCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGY----EGVHCEVNTDECA 495
Query: 556 QEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGG---VCI 612
P + C + + + C+CP G+ D + C+ G C+
Sbjct: 496 SSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECAS--TPCKNGAKCLDGPNTYTCV 553
Query: 613 NTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXX 672
T+G C+ + D C G+C + + C
Sbjct: 554 CTEGYTGTHCEVDIDEC-DPDPC---HYGSCKDGVATFTCLCRPGYTGHHCETNINECSS 609
Query: 673 XXXXXGHVTK----AQCCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXX 728
G + A C L G CE+ LD C +
Sbjct: 610 QPCRHGGTCQDRDNAYLCFCLKGTTGPNCEI--------NLDDCASSPCDSGTCLDKIDG 661
Query: 729 XXXXXXXXXXXXXLDVFADVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVCADVD 782
++ ++DECA P G C G F C C GY ++V+
Sbjct: 662 YECACEPGYTGSMCNI--NIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDP-TCLSEVN 718
Query: 783 ECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNT 839
EC PC C ++ Y C C G+ G NC D++ E +++ C C +
Sbjct: 719 EC--NSNPCVHGACRDSLNGYKCDCDPGWS----GTNC-DINNNECESNPCVNGGTCKDM 771
Query: 840 EGSYECSCEDGY 851
Y C+C +G+
Sbjct: 772 TSGYVCTCREGF 783
Score = 213 bits (521), Expect = 2e-54
Identities = 186/609 (30%), Positives = 259/609 (42%), Gaps = 98/609 (16%)
Query: 69 DECDIMPQLCKPGT-CHDTPTGFQ--CGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMA 124
D C P C G+ C P + C C GY T C +DVDECS G PC
Sbjct: 374 DACISNP--CNEGSNCDTNPVNGKAICTCPSGY----TGPACSQDVDECSLGANPCEHAG 427
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYT 183
+C+N G+FEC+C GY + CE DV+EC + C + IG ++C C PGY
Sbjct: 428 KCINTLGSFECQCLQGY----TGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGY- 482
Query: 184 LRENV-CR-DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGG 240
E V C + DEC+ P NG C + + C C GF + C DV+EC
Sbjct: 483 --EGVHCEVNTDECA-SSPCLHNGRCLDKINEFQCECPTGF---TGHLCQYDVDEC--AS 534
Query: 241 MVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNG 298
C+NG +C + ++ C C GYT G +C D+DECD P PC SC +
Sbjct: 535 TPCKNGAKCLDGPNTYTCVCTEGYT----GTHCEVDIDECD--PDPCHYG---SCKDGVA 585
Query: 299 GYECSCGAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAV 356
+ C C G+ G C + +EC P C GG C++ + Y+C C G T
Sbjct: 586 TFTCLCRPGY--TGHHCETNINECSSQP--CRHGGTCQDRDNAYLCFCLKG----TTGPN 637
Query: 357 CVDERKELCYDEWEAGRCHRARPL-QLARPECCCSEGAAWGRYC----ERC---PAPDSA 408
C E+ D+ + C L ++ EC C G G C + C P +
Sbjct: 638 C-----EINLDDCASSPCDSGTCLDKIDGYECACEPGYT-GSMCNINIDECAGNPCHNGG 691
Query: 409 E-------FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAP 461
F C G P +++EC P CV G C ++ ++C+C G+
Sbjct: 692 TCEDGINGFTCRCPEGYHDPTCLSEVNECNSNP--CVHGACRDSLNGYKCDCDPGW---- 745
Query: 462 DGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRAS 519
G +C ++ +EC +P + G GTC + GY C C GF+ GP+ QT +++ECA
Sbjct: 746 SGTNCDINNNECESNPCVNG-GTCKDMTSGYVCTCREGFS-GPNCQT--NINECASNPCL 801
Query: 520 CTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI-DECVQEPRVCPHACENV--VGSYICKC 576
C + ++C C Y G C + C P C S+ C C
Sbjct: 802 NQGTCIDDVAGYKCNCLLPYT----GATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVC 857
Query: 577 PEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
P G++ CE DINEC G C NT G + C C AG+ TD
Sbjct: 858 PTGWQ--------GQTCEVDINEC-VLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDI 908
Query: 636 IDRRTGTCY 644
D R C+
Sbjct: 909 DDCRPNPCH 917
Score = 200 bits (489), Expect = 1e-50
Identities = 188/642 (29%), Positives = 258/642 (40%), Gaps = 103/642 (16%)
Query: 60 PVTNETKPIDECDIMPQLCKPG-TCHDTPT--GFQCGCDHGYEHDNTSHLCR-DVDECSW 115
P T T + P C+ G C + F C C G++ C D++EC
Sbjct: 820 PYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQ----GQTCEVDINECVL 875
Query: 116 GRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSY 174
PCR A C N G + C C GY S CE D+D+C + G C + I +
Sbjct: 876 S--PCRHGASCQNTHGGYRCHCQAGY----SGRNCETDIDDCRPNPCHNGGSCTDGINTA 929
Query: 175 RCECKPGYTLRENVCR-DVDECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVD 232
C+C PG+ R C D++EC+ CRNG C + +Y C C GF + +
Sbjct: 930 FCDCLPGF--RGTFCEEDINECASDP--CRNGANCTDCVDSYTCTCPAGFSGIHCEN--N 983
Query: 233 VNECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGN 290
+C E C NG C + + SF C C PG+T G C+ DV+ECD PC G
Sbjct: 984 TPDCTESS--CFNGGTCVDGINSFTCLCPPGFT----GSYCQHDVNECDS--QPCLHGG- 1034
Query: 291 PSCTNTNGGYECSCGAGWKLVGRRCVDRDE-CKELPYVCA-GGECRNFNGGYVCECPAGW 348
+C + G Y C+C G+ G C + C P C GG+C + Y CECP+GW
Sbjct: 1035 -TCQDGCGSYRCTCPQGY--TGPNCQNLVHWCDSSP--CKNGGKCWQTHTQYRCECPSGW 1089
Query: 349 R---FDKTAAVCVDERKELCYDEWEAGRC-HRARPLQLARPECCCSEGAAWGRYCE---- 400
D + C + D A C H + C + G YCE
Sbjct: 1090 TGLYCDVPSVSCEVAAQRQGVD--VARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVD 1147
Query: 401 RC-PAPDS---------AEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSF 449
C P+P + C G N ++++DEC P C GG C++ ++
Sbjct: 1148 ECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHP--CQNGGTCLDLPNTY 1205
Query: 450 RCECPDGYVLAPDGLSC-VDADEC-------ALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
+C CP G G+ C ++ D+C + P+ NGTC + GGY C C PGF
Sbjct: 1206 KCSCPRG----TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV- 1260
Query: 502 GPDQTCV-DVDECAEG--RASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQE 557
+ C DV+EC A T C F C C G+ G C I+ C +
Sbjct: 1261 --GERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHT----GRRCESVINGCKGK 1314
Query: 558 PRVCPHAC---ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINT 614
P C N +ICKCP G+ + D+ C + C +GG CI+
Sbjct: 1315 PCKNGGTCAVASNTARGFICKCPAGFEGATCENDA-RTCGSL-RC------LNGGTCISG 1366
Query: 615 DGSFLCDCDAGFEPSEDGTDCIDRRTG--TCYRSLVSGRCEP 654
S C C F E G CY G CEP
Sbjct: 1367 PRSPTCLCLGPFTGPECQFPASSPCLGGNPCYN---QGTCEP 1405
Score = 195 bits (475), Expect = 6e-49
Identities = 186/662 (28%), Positives = 270/662 (40%), Gaps = 117/662 (17%)
Query: 19 TKYLCCCSVGHAWGAPCEACPPRGS----------PAHTALCGEKPGEYINPVTNETKPI 68
T+Y C C G + G C+ P S P + P + P + +
Sbjct: 123 TEYKCRCPPGWS-GKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQD--V 179
Query: 69 DECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+EC P LC+ G TCH+ ++C C + N R CS PC+ C
Sbjct: 180 NECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCE---RPYVPCS--PSPCQNGGTCR 234
Query: 128 NLPGA-FECRCPPGYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
EC C PG+ + CE+ +D+C + G C + + +Y C C P +T
Sbjct: 235 PTGDVTHECACLPGF----TGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWT-G 289
Query: 186 ENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVD-VNECREGGMVC 243
+ DVDEC C+N GTC N G Y C C +G+ DC + +++C C
Sbjct: 290 QYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW---TGEDCSENIDDC--ASAAC 344
Query: 244 RNG-RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC 302
+G C + V SF CEC G T G C D C + +PC N NG C
Sbjct: 345 FHGATCHDRVASFYCECPHGRT----GLLCHLNDAC--ISNPCNEGSNCDTNPVNGKAIC 398
Query: 303 SCGAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
+C +G+ G C D DEC C G+C N G + C+C G+ T C
Sbjct: 399 TCPSGY--TGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY----TGPRC--- 449
Query: 361 RKELCYDEWEAGRCHRARPL--QLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
E+ +E + C Q+ +C C G G +CE
Sbjct: 450 --EIDVNECVSNPCQNDATCLDQIGEFQCICMPGYE-GVHCE------------------ 488
Query: 419 GRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPR 477
+ DEC P C+ GRC++ F+CECP G+ L D DECA P
Sbjct: 489 ------VNTDECASSP--CLHNGRCLDKINEFQCECPTGFT---GHLCQYDVDECASTP- 536
Query: 478 ICGNGT-CSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRCTC 535
C NG C + Y C C+ G+T + VD+DEC C + C + +F C C
Sbjct: 537 -CKNGAKCLDGPNTYTCVCTEGYTGTHCE--VDIDECDPD--PCHYGSCKDGVATFTCLC 591
Query: 536 PYGYAVAADGVHCR-DIDECVQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENA 592
GY G HC +I+EC +P C H C++ +Y+C C +G T+ P
Sbjct: 592 RPGYT----GHHCETNINECSSQP--CRHGGTCQDRDNAYLCFCLKG---TTGPN----- 637
Query: 593 CE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGR 651
CE ++++C C G C++ + C C+ G+ S + + C+ G
Sbjct: 638 CEINLDDCASSP--CDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHN---GGT 692
Query: 652 CE 653
CE
Sbjct: 693 CE 694
Score = 185 bits (451), Expect = 5e-46
Identities = 155/463 (33%), Positives = 190/463 (41%), Gaps = 73/463 (15%)
Query: 195 CSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRC---- 248
CS+P C NG CE G C C F GP C D N C C+N G C
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAF-VGPR--CQDPNPCLS--TPCKNAGTCHVVD 78
Query: 249 RNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
R V + C CA G++ G C + L +PC R+G T Y+C C GW
Sbjct: 79 RRGVADYACSCALGFS----GPLCLTPLDNACLTNPC-RNGGTCDLLTLTEYKCRCPPGW 133
Query: 309 KLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDE---RKEL 364
G+ C D C P CA GG+C F Y+C CP + T V+E + L
Sbjct: 134 S--GKSCQQADPCASNP--CANGGQCLPFEASYICHCPPSFH-GPTCRQDVNECGQKPGL 188
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQ-GGMGRP-- 421
C G CH ++ C C G CER P S CQ GG RP
Sbjct: 189 CR---HGGTCHN----EVGSYRCVC-RATHTGPNCERPYVPCSPS---PCQNGGTCRPTG 237
Query: 422 NLTQDL--------DECRVRPDVCVGGRCVN----TDG--SFRCECPDGYVLAPDGLSCV 467
++T + C D C G C N DG ++ C CP + G C
Sbjct: 238 DVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWT----GQYCT 293
Query: 468 -DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
D DEC L P C NG TC NT GGY C C G+T G D ++D+CA CH
Sbjct: 294 EDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWT-GED-CSENIDDCASAACFHGATCH 351
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN--VVGSYICKCPEGYRRT 583
+ SF C CP+G G+ C D C+ P C+ V G IC CP GY
Sbjct: 352 DRVASFYCECPHG----RTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGP 407
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
+ QD + N CE G CINT GSF C C G+
Sbjct: 408 ACSQDVDECSLGANPCEH------AGKCINTLGSFECQCLQGY 444
Score = 147 bits (355), Expect = 2e-34
Identities = 169/582 (29%), Positives = 226/582 (38%), Gaps = 93/582 (15%)
Query: 21 YLCCCSVGHAWGAPCEA----CPPR-----GSPA---HTALCGEKPGEYINPVTNETKPI 68
Y C C G++ G CE C P GS +TA C PG + E I
Sbjct: 891 YRCHCQAGYS-GRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPG-FRGTFCEED--I 946
Query: 69 DECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+EC P C+ G C D + C C G+ + + D E S C CV
Sbjct: 947 NECASDP--CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESS-----CFNGGTCV 999
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
+ +F C CPPG+ T S + DV+EC Q G C++ GSYRC C GYT
Sbjct: 1000 DGINSFTCLCPPGF--TGSYCQ-HDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPN- 1055
Query: 188 VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA----GPNNDCVDVNECREGGMVC 243
C+++ P G C Y C C G+ P+ C +V R+G V
Sbjct: 1056 -CQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSC-EVAAQRQGVDVA 1113
Query: 244 R----NGRCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNG 298
R G C + + C C GYT G C D VDEC P PC +CT+ G
Sbjct: 1114 RLCQHGGLCVDAGNTHHCRCQAGYT----GSYCEDLVDECS--PSPC--QNGATCTDYLG 1165
Query: 299 GYECSCGAGWKLVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAV 356
GY C C AG+ G C + DEC L + C GG C + Y C CP G + +
Sbjct: 1166 GYSCKCVAGYH--GVNCSEEIDEC--LSHPCQNGGTCLDLPNTYKCSCPRGTQ-GVHCEI 1220
Query: 357 CVDERKELCYDEWEAGRCHRARPL--QLARPECCCSEGAAWGRYCE---------RCPAP 405
VD+ + +C Q+ C C G G CE C A
Sbjct: 1221 NVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV-GERCEGDVNECLSNPCDAR 1279
Query: 406 DSA-------EFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCV---NTDGSFRCECP 454
+ +F C+ G ++ C+ +P C GG C NT F C+CP
Sbjct: 1280 GTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKP--CKNGGTCAVASNTARGFICKCP 1337
Query: 455 DGYVLAPDGLSCV-DADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDEC 513
G+ +G +C DA C R GTC + C C FT GP+ C
Sbjct: 1338 AGF----EGATCENDARTCG-SLRCLNGGTCISGPRSPTCLCLGPFT-GPECQFPASSPC 1391
Query: 514 AEGRASCT-FRCHNTAGS--FRCTCPYGYAVAADGVHCRDID 552
G C T+ S +RC CP + +G+ C +D
Sbjct: 1392 LGGNPCYNQGTCEPTSESPFYRCLCPAKF----NGLLCHILD 1429
Score = 66.5 bits (155), Expect = 4e-10
Identities = 72/263 (27%), Positives = 96/263 (36%), Gaps = 35/263 (13%)
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
P+D P+ GTC D G+ C C G+ + DV+EC RG C
Sbjct: 1228 PVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE---GDVNECLSNPCDARGTQNC 1284
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDV-DECGDQRICDHGDC---RNTIGSYRCECKPGY 182
V F C C G+ + CE V + C + + G C NT + C+C G+
Sbjct: 1285 VQRVNDFHCECRAGH----TGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGF 1340
Query: 183 TLRENVC-RDVDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGG 240
C D C R C N GTC + P + C C F GP + C G
Sbjct: 1341 --EGATCENDARTCGSLR--CLNGGTCISGPRSPTCLCLGPF-TGPECQFPASSPCLGGN 1395
Query: 241 MVCRNGRCRNTVGS--FRCECAPGYT--------LTADGRNCRD-----VDECDELPHPC 285
G C T S +RC C + + G RD ++E ELP C
Sbjct: 1396 PCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPE-C 1454
Query: 286 GRD-GNPSCTNTNGGYECSCGAG 307
D GN C+ + C G
Sbjct: 1455 QEDAGNKVCSLQCNNHACGWDGG 1477
Score = 64.9 bits (151), Expect = 1e-09
Identities = 36/96 (37%), Positives = 48/96 (50%), Gaps = 10/96 (10%)
Query: 761 GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDEDGA 817
G+ C C GY G C+ DVDEC++ PC+ C NT GS++C C GY G
Sbjct: 394 GKAICTCPSGY--TGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYT----GP 447
Query: 818 NCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
C DV+EC + C + G ++C C GYE
Sbjct: 448 RCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYE 483
Score = 50.4 bits (115), Expect = 3e-05
Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 15/110 (13%)
Query: 756 GLCAPG---RFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYE 811
G C P C C PG+ G+ C + +D+C C + +Y+C C +
Sbjct: 231 GTCRPTGDVTHECACLPGF--TGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWT 288
Query: 812 LDEDGANC-RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
G C DVDEC+ + CQ C NT G Y C C +G+ G+ C
Sbjct: 289 ----GQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW--TGEDC 332
Score = 46.4 bits (105), Expect = 4e-04
Identities = 34/102 (33%), Positives = 46/102 (45%), Gaps = 19/102 (18%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCD----QLCHNTDGSYDCLCRTGYELDED 815
G + C C PG+ GE C DV+EC P CD Q C + C CR G+
Sbjct: 1249 GGYSCTCPPGF--VGERCEGDVNECLSNP--CDARGTQNCVQRVNDFHCECRAGHT---- 1300
Query: 816 GANCRDV-DECE----RDTHTCQQICSNTEGSYECSCEDGYE 852
G C V + C+ ++ TC + SNT + C C G+E
Sbjct: 1301 GRRCESVINGCKGKPCKNGGTCA-VASNTARGFICKCPAGFE 1341
Score = 45.6 bits (103), Expect = 8e-04
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 19/123 (15%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHN 797
DVDEC +P C G + CVC G+ GE C++ +D+CA CH+
Sbjct: 295 DVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW--TGEDCSENIDDCASAACFHGATCHD 352
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSN--TEGSYECSCEDGYEKRG 855
S+ C C G G C D C + C G C+C GY G
Sbjct: 353 RVASFYCECPHG----RTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGY--TG 406
Query: 856 DAC 858
AC
Sbjct: 407 PAC 409
Score = 31.9 bits (69), Expect = 10.0
Identities = 26/99 (26%), Positives = 36/99 (36%), Gaps = 11/99 (11%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHN-TDGSYDCLCRTGYELDEDGANC 819
+ C C G+ +G +C + A PC C T Y C C G+ G +C
Sbjct: 85 YACSCALGF--SGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWS----GKSC 138
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
+ D C + C E SY C C + G C
Sbjct: 139 QQADPCASNPCANGGQCLPFEASYICHCPPSF--HGPTC 175
>AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein
variant protein.
Length = 2067
Score = 256 bits (628), Expect = 2e-67
Identities = 241/847 (28%), Positives = 345/847 (40%), Gaps = 127/847 (14%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCV 127
DEC P L G C D FQC C G+ T HLC+ DVDEC+ PC+ A+C+
Sbjct: 4 DECASSPCLHN-GRCLDKINEFQCECPTGF----TGHLCQYDVDECA--STPCKNGAKCL 56
Query: 128 NLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
+ P + C C GY T CE D+DEC D C +G C++ + ++ C C+PGYT
Sbjct: 57 DGPNTYTCVCTEGYTGT----HCEVDIDEC-DPDPCHYGSCKDGVATFTCLCRPGYT-GH 110
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
+ +++ECS +P GTC++ AYLC C G GPN + +++++C C +G
Sbjct: 111 HCETNINECS-SQPCRHGGTCQDRDNAYLCFCLKG-TTGPNCE-INLDDC--ASSPCDSG 165
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C + + + C C PGYT G C ++DEC +PC G +C + G+ C C
Sbjct: 166 TCLDKIDGYECACEPGYT----GSMCNINIDEC--AGNPCHNGG--TCEDGINGFTCRCP 217
Query: 306 AGWKLVGRRCVDR-DECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKEL 364
G+ C+ +EC P C G CR+ GY C+C GW + C ++
Sbjct: 218 EGYH--DPTCLSEVNECNSNP--CVHGACRDSLNGYKCDCDPGW----SGTNC-----DI 264
Query: 365 CYDEWEAGRCHRARPLQ--LARPECCCSEGAAWGRYCE----RC---PAPDSAEFMRICQ 415
+E E+ C + + C C EG + G C+ C P + +
Sbjct: 265 NNNECESNPCVNGGTCKDMTSGYVCTCREGFS-GPNCQTNINECASNPCLNQGTCIDDVA 323
Query: 416 GGMGRPNLTQDLDECRV-----RPDVC-VGGRCVNTDG--SFRCECPDGYVLAPDGLSC- 466
G L C V P C GG C ++ SF C CP G+ G +C
Sbjct: 324 GYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGW----QGQTCE 379
Query: 467 VDADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
VD +EC L P C +G +C NT GGY C C G++ +T D+D+C C
Sbjct: 380 VDINECVLSP--CRHGASCQNTHGGYRCHCQAGYSGRNCET--DIDDCRPNPCHNGGSCT 435
Query: 526 NTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
+ + C C G+ G C DI+EC +P C + V SY C CP G+
Sbjct: 436 DGINTAFCDCLPGFR----GTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGF---- 487
Query: 585 APQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFEPS---EDGTDCIDR-- 638
S CE+ N + E C +GG C++ SF C C GF S D +C +
Sbjct: 488 ----SGIHCEN-NTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPC 542
Query: 639 -RTGTCYRSLVSGRCE-PEXXXXXXXXXXXXXXXXXXXXXXGHV--TKAQCCCTLGAAW- 693
GTC S RC P+ G T Q C + W
Sbjct: 543 LHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWT 602
Query: 694 GSECEL----CPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVD 749
G C++ C +D+ D+ VD
Sbjct: 603 GLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDL---VD 659
Query: 750 ECAAIP----GLCAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSY 802
EC+ P C G + C C GY G C+ ++DEC P C + +Y
Sbjct: 660 ECSPSPCQNGATCTDYLGGYSCKCVAGYH--GVNCSEEIDECLSHPCQNGGTCLDLPNTY 717
Query: 803 DCLCRTGYELDEDGANCR-DVDECERDTHTCQQ--------ICSNTEGSYECSCEDGYEK 853
C C G + G +C +VD+C + C + G Y C+C G+
Sbjct: 718 KCSCPRGTQ----GVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV- 772
Query: 854 RGDACVG 860
G+ C G
Sbjct: 773 -GERCEG 778
Score = 228 bits (558), Expect = 6e-59
Identities = 189/634 (29%), Positives = 280/634 (44%), Gaps = 91/634 (14%)
Query: 19 TKYLCCCSVGHAWGAPCE--ACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQ 76
T +LC V PC+ A G +T +C E Y T+ IDECD P
Sbjct: 33 TGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEG---YTG--THCEVDIDECD--PD 85
Query: 77 LCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFEC 135
C G+C D F C C GY T H C +++ECS PCR C + A+ C
Sbjct: 86 PCHYGSCKDGVATFTCLCRPGY----TGHHCETNINECS--SQPCRHGGTCQDRDNAYLC 139
Query: 136 RCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVD 193
C G + CE ++D+C CD G C + I Y C C+PGYT ++C ++D
Sbjct: 140 FCLKG----TTGPNCEINLDDCASSP-CDSGTCLDKIDGYECACEPGYT--GSMCNINID 192
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCV-DVNECREGGMVCRNGRCRNTV 252
EC+ P GTCE+ + C C +G+ + C+ +VNEC C +G CR+++
Sbjct: 193 ECA-GNPCHNGGTCEDGINGFTCRCPEGYH---DPTCLSEVNECNSN--PCVHGACRDSL 246
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
++C+C PG++ G NC D++ + +PC G +C + GY C+C G+ G
Sbjct: 247 NGYKCDCDPGWS----GTNC-DINNNECESNPCVNGG--TCKDMTSGYVCTCREGFS--G 297
Query: 313 RRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEA 371
C + +EC P + G C + GY C C + V C +
Sbjct: 298 PNCQTNINECASNPCL-NQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRN---G 353
Query: 372 GRCHRARPLQLARPECCCSEGAAW-GRYCE----RC---PAPDSAEFMRI-------CQG 416
G C ++ + C C G W G+ CE C P A CQ
Sbjct: 354 GECRQSEDYESF--SCVCPTG--WQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQA 409
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECAL 474
G N D+D+C RP+ C GG C + + C+C G+ G C D +ECA
Sbjct: 410 GYSGRNCETDIDDC--RPNPCHNGGSCTDGINTAFCDCLPGF----RGTFCEEDINECAS 463
Query: 475 DPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRC 533
DP C NG C++ Y C C GF+ + + +C E C + SF C
Sbjct: 464 DP--CRNGANCTDCVDSYTCTCPAGFSGIHCEN--NTPDCTESSCFNGGTCVDGINSFTC 519
Query: 534 TCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
CP G+ G +C+ D++EC +P + C++ GSY C CP+GY + Q+ +
Sbjct: 520 LCPPGFT----GSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNC-QNLVHW 574
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
C D + C+ +GG C T + C+C +G+
Sbjct: 575 C-DSSPCK------NGGKCWQTHTQYRCECPSGW 601
Score = 209 bits (510), Expect = 4e-53
Identities = 194/678 (28%), Positives = 278/678 (41%), Gaps = 97/678 (14%)
Query: 19 TKYLCCCSVGHAWGAPCE---ACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMP 75
T +C ++ G PC C G T C P Y +P ++EC+ P
Sbjct: 183 TGSMCNINIDECAGNPCHNGGTCED-GINGFTCRC---PEGYHDPTC--LSEVNECNSNP 236
Query: 76 QLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC 135
C G C D+ G++C CD G+ N C D++ PC C ++ + C
Sbjct: 237 --CVHGACRDSLNGYKCDCDPGWSGTN----C-DINNNECESNPCVNGGTCKDMTSGYVC 289
Query: 136 RCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDE 194
C G+ S C+ +++EC + G C + + Y+C C YT C V
Sbjct: 290 TCREGF----SGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYT--GATCEVVLA 343
Query: 195 CSRPRPVCRNG-TCENLPG--AYLCHCDDGFKAGPNNDC-VDVNECREGGMVCRNGR-CR 249
P P CRNG C ++ C C G++ C VD+NEC CR+G C+
Sbjct: 344 PCAPSP-CRNGGECRQSEDYESFSCVCPTGWQG---QTCEVDINECVLSP--CRHGASCQ 397
Query: 250 NTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
NT G +RC C GY+ GRNC D+D+C P+PC G SCT+ C C G+
Sbjct: 398 NTHGGYRCHCQAGYS----GRNCETDIDDCR--PNPCHNGG--SCTDGINTAFCDCLPGF 449
Query: 309 KLVGRRCV-DRDECKELPYVCAGG-ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCY 366
+ G C D +EC P C G C + Y C CPAG+ D + C+
Sbjct: 450 R--GTFCEEDINECASDP--CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCF 505
Query: 367 DEWEAGRCHRARPLQLARPECCCSEGAAWGRYCER-CPAPDSAEFMR--ICQGGMGR--- 420
+ G C + C C G G YC+ DS + CQ G G
Sbjct: 506 N---GGTCVDG----INSFTCLCPPGFT-GSYCQHDVNECDSQPCLHGGTCQDGCGSYRC 557
Query: 421 --------PNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYV-LAPD--GLSC-V 467
PN + C P C GG+C T +RCECP G+ L D +SC V
Sbjct: 558 TCPQGYTGPNCQNLVHWCDSSP--CKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEV 615
Query: 468 DADECALD-PRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVD-VDECAEGRASCTFRC 524
A +D R+C +G C + + C+C G+T C D VDEC+ C
Sbjct: 616 AAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT---GSYCEDLVDECSPSPCQNGATC 672
Query: 525 HNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVCPHACENVVGSYICKCPEGYRRT 583
+ G + C C GY GV+C +IDEC+ P C ++ +Y C CP G +
Sbjct: 673 TDYLGGYSCKCVAGY----HGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGV 728
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF--EPSE-DGTDCID--- 637
+ ++ ++ + G C++ G + C C GF E E D +C+
Sbjct: 729 HCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPC 788
Query: 638 --RRTGTCYRSLVSGRCE 653
R T C + + CE
Sbjct: 789 DARGTQNCVQRVNDFHCE 806
Score = 194 bits (472), Expect = 1e-48
Identities = 194/624 (31%), Positives = 261/624 (41%), Gaps = 111/624 (17%)
Query: 60 PVTNETKPIDECDIMPQLCKPG-TCHDTPT--GFQCGCDHGYEHDNTSHLCR-DVDECSW 115
P T T + P C+ G C + F C C G++ C D++EC
Sbjct: 332 PYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQ----GQTCEVDINECVL 387
Query: 116 GRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSY 174
PCR A C N G + C C GY S CE D+D+C + G C + I +
Sbjct: 388 S--PCRHGASCQNTHGGYRCHCQAGY----SGRNCETDIDDCRPNPCHNGGSCTDGINTA 441
Query: 175 RCECKPGYTLRENVCR-DVDECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVD 232
C+C PG+ R C D++EC+ CRNG C + +Y C C GF + +
Sbjct: 442 FCDCLPGF--RGTFCEEDINECASDP--CRNGANCTDCVDSYTCTCPAGFSGIHCEN--N 495
Query: 233 VNECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGN 290
+C E C NG C + + SF C C PG+T G C+ DV+ECD PC G
Sbjct: 496 TPDCTESS--CFNGGTCVDGINSFTCLCPPGFT----GSYCQHDVNECDS--QPCLHGG- 546
Query: 291 PSCTNTNGGYECSCGAGWKLVGRRCVDRDE-CKELPYVCA-GGECRNFNGGYVCECPAGW 348
+C + G Y C+C G+ G C + C P C GG+C + Y CECP+GW
Sbjct: 547 -TCQDGCGSYRCTCPQGY--TGPNCQNLVHWCDSSP--CKNGGKCWQTHTQYRCECPSGW 601
Query: 349 RFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSA 408
T C D C E A R + + +AR C G C +
Sbjct: 602 ----TGLYC-DVPSVSC--EVAAQR----QGVDVAR---LCQHGGL-------CVDAGNT 640
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCV 467
R CQ G +DEC P C G C + G + C+C GY G++C
Sbjct: 641 HHCR-CQAGYTGSYCEDLVDECS--PSPCQNGATCTDYLGGYSCKCVAGY----HGVNCS 693
Query: 468 DA-DECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAE-----GRASC 520
+ DEC P C NG TC + Y+C C G TQG ++VD+C R+
Sbjct: 694 EEIDECLSHP--CQNGGTCLDLPNTYKCSCPRG-TQGVHCE-INVDDCNPPVDPVSRSPK 749
Query: 521 TFR---CHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVC--PHACENVVGSYIC 574
F C + G + CTCP G+ G C D++EC+ P C V + C
Sbjct: 750 CFNNGTCVDQVGGYSCTCPPGFV----GERCEGDVNECLSNPCDARGTQNCVQRVNDFHC 805
Query: 575 KCPEGYRRTSAPQDSENACED-INECEEQEDLC-SGGVCI---NTDGSFLCDCDAGFEPS 629
+C G+ + CE IN C+ + C +GG C NT F+C C AGFE
Sbjct: 806 ECRAGH--------TGRRCESVINGCKGKP--CKNGGTCAVASNTARGFICKCPAGFE-- 853
Query: 630 EDGTDC-IDRRTGTCYRSLVSGRC 652
G C D RT R L G C
Sbjct: 854 --GATCENDARTCGSLRCLNGGTC 875
Score = 184 bits (449), Expect = 9e-46
Identities = 159/539 (29%), Positives = 223/539 (41%), Gaps = 84/539 (15%)
Query: 152 DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGT-CEN 209
+ DEC +G C + I ++CEC G+T ++C+ DVDEC+ C+NG C +
Sbjct: 2 NTDECASSPCLHNGRCLDKINEFQCECPTGFT--GHLCQYDVDECASTP--CKNGAKCLD 57
Query: 210 LPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADG 269
P Y C C +G+ G + + VD++EC C G C++ V +F C C PGYT G
Sbjct: 58 GPNTYTCVCTEGY-TGTHCE-VDIDECDPDP--CHYGSCKDGVATFTCLCRPGYT----G 109
Query: 270 RNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYV 327
+C +++EC PC G +C + + Y C C G G C ++ D+C P
Sbjct: 110 HHCETNINECSS--QPCRHGG--TCQDRDNAYLCFCLKG--TTGPNCEINLDDCASSP-- 161
Query: 328 CAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE-------RKELCYDEWEAGRCHRARPL 380
C G C + GY C C G+ + +DE C D C P
Sbjct: 162 CDSGTCLDKIDGYECACEPGYT-GSMCNINIDECAGNPCHNGGTCEDGINGFTCRC--PE 218
Query: 381 QLARPECCCSEGAAWGRYCERCPAPDSAEFMRI-CQGGMGRPNLTQDLDECRVRPDVCV- 438
P C C DS + C G N + +EC P CV
Sbjct: 219 GYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNP--CVN 276
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSP 497
GG C + + C C +G+ G +C + +ECA +P + GTC + GY+C C
Sbjct: 277 GGTCKDMTSGYVCTCREGF----SGPNCQTNINECASNPCL-NQGTCIDDVAGYKCNCLL 331
Query: 498 GFTQGPDQTC-VDVDECAEGRASCTFRCHNTAG--SFRCTCPYGYAVAADGVHCR-DIDE 553
+T TC V + CA C + SF C CP G+ G C DI+E
Sbjct: 332 PYTGA---TCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGW----QGQTCEVDINE 384
Query: 554 CVQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVC 611
CV P C H +C+N G Y C C GY N DI++C +GG C
Sbjct: 385 CVLSP--CRHGASCQNTHGGYRCHCQAGY-------SGRNCETDIDDC-RPNPCHNGGSC 434
Query: 612 INTDGSFLCDCDAGF--------------EPSEDG---TDCIDRRTGTCYRSLVSGRCE 653
+ + CDC GF +P +G TDC+D T TC CE
Sbjct: 435 TDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCE 493
Score = 147 bits (355), Expect = 2e-34
Identities = 169/582 (29%), Positives = 226/582 (38%), Gaps = 93/582 (15%)
Query: 21 YLCCCSVGHAWGAPCEA----CPPR-----GSPA---HTALCGEKPGEYINPVTNETKPI 68
Y C C G++ G CE C P GS +TA C PG + E I
Sbjct: 403 YRCHCQAGYS-GRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPG-FRGTFCEED--I 458
Query: 69 DECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+EC P C+ G C D + C C G+ + + D E S C CV
Sbjct: 459 NECASDP--CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESS-----CFNGGTCV 511
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
+ +F C CPPG+ T S + DV+EC Q G C++ GSYRC C GYT
Sbjct: 512 DGINSFTCLCPPGF--TGSYCQ-HDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPN- 567
Query: 188 VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA----GPNNDCVDVNECREGGMVC 243
C+++ P G C Y C C G+ P+ C +V R+G V
Sbjct: 568 -CQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSC-EVAAQRQGVDVA 625
Query: 244 R----NGRCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNG 298
R G C + + C C GYT G C D VDEC P PC +CT+ G
Sbjct: 626 RLCQHGGLCVDAGNTHHCRCQAGYT----GSYCEDLVDECS--PSPC--QNGATCTDYLG 677
Query: 299 GYECSCGAGWKLVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAV 356
GY C C AG+ G C + DEC L + C GG C + Y C CP G + +
Sbjct: 678 GYSCKCVAGYH--GVNCSEEIDEC--LSHPCQNGGTCLDLPNTYKCSCPRGTQ-GVHCEI 732
Query: 357 CVDERKELCYDEWEAGRCHRARPL--QLARPECCCSEGAAWGRYCE---------RCPAP 405
VD+ + +C Q+ C C G G CE C A
Sbjct: 733 NVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV-GERCEGDVNECLSNPCDAR 791
Query: 406 DSA-------EFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCV---NTDGSFRCECP 454
+ +F C+ G ++ C+ +P C GG C NT F C+CP
Sbjct: 792 GTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKP--CKNGGTCAVASNTARGFICKCP 849
Query: 455 DGYVLAPDGLSCV-DADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDEC 513
G+ +G +C DA C R GTC + C C FT GP+ C
Sbjct: 850 AGF----EGATCENDARTCG-SLRCLNGGTCISGPRSPTCLCLGPFT-GPECQFPASSPC 903
Query: 514 AEGRASCT-FRCHNTAGS--FRCTCPYGYAVAADGVHCRDID 552
G C T+ S +RC CP + +G+ C +D
Sbjct: 904 LGGNPCYNQGTCEPTSESPFYRCLCPAKF----NGLLCHILD 941
Score = 66.5 bits (155), Expect = 4e-10
Identities = 72/263 (27%), Positives = 96/263 (36%), Gaps = 35/263 (13%)
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
P+D P+ GTC D G+ C C G+ + DV+EC RG C
Sbjct: 740 PVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE---GDVNECLSNPCDARGTQNC 796
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDV-DECGDQRICDHGDC---RNTIGSYRCECKPGY 182
V F C C G+ + CE V + C + + G C NT + C+C G+
Sbjct: 797 VQRVNDFHCECRAGH----TGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGF 852
Query: 183 TLRENVC-RDVDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGG 240
C D C R C N GTC + P + C C F GP + C G
Sbjct: 853 --EGATCENDARTCGSLR--CLNGGTCISGPRSPTCLCLGPF-TGPECQFPASSPCLGGN 907
Query: 241 MVCRNGRCRNTVGS--FRCECAPGYT--------LTADGRNCRD-----VDECDELPHPC 285
G C T S +RC C + + G RD ++E ELP C
Sbjct: 908 PCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPE-C 966
Query: 286 GRD-GNPSCTNTNGGYECSCGAG 307
D GN C+ + C G
Sbjct: 967 QEDAGNKVCSLQCNNHACGWDGG 989
Score = 60.5 bits (140), Expect = 2e-08
Identities = 39/114 (34%), Positives = 53/114 (46%), Gaps = 17/114 (14%)
Query: 747 DVDECAAIP----GLCAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+ DECA+ P G C F+C C G+ G +C DVDECA P C +
Sbjct: 2 NTDECASSPCLHNGRCLDKINEFQCECPTGF--TGHLCQYDVDECASTPCKNGAKCLDGP 59
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQ-ICSNTEGSYECSCEDGY 851
+Y C+C GY G +C D+DEC+ D C C + ++ C C GY
Sbjct: 60 NTYTCVCTEGY----TGTHCEVDIDECDPD--PCHYGSCKDGVATFTCLCRPGY 107
Score = 46.4 bits (105), Expect = 4e-04
Identities = 34/102 (33%), Positives = 46/102 (45%), Gaps = 19/102 (18%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCD----QLCHNTDGSYDCLCRTGYELDED 815
G + C C PG+ GE C DV+EC P CD Q C + C CR G+
Sbjct: 761 GGYSCTCPPGF--VGERCEGDVNECLSNP--CDARGTQNCVQRVNDFHCECRAGHT---- 812
Query: 816 GANCRDV-DECE----RDTHTCQQICSNTEGSYECSCEDGYE 852
G C V + C+ ++ TC + SNT + C C G+E
Sbjct: 813 GRRCESVINGCKGKPCKNGGTCA-VASNTARGFICKCPAGFE 853
>AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein.
Length = 1231
Score = 252 bits (617), Expect = 4e-66
Identities = 188/569 (33%), Positives = 245/569 (43%), Gaps = 84/569 (14%)
Query: 69 DECDIMP-QLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
DEC ++P +LC+ C +T + C C G+ + CR G PP Q
Sbjct: 606 DECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPE-----GHPPQPEAPQEP 659
Query: 128 NLPGAFECRCPPGYRL-TPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
L F L P + C+D C +++C GS C C PGY +
Sbjct: 660 ALKSEFSQVASNTIPLPLPQPNTCKDNGPC--KQVCS-----TVGGSAICSCFPGYAIMA 712
Query: 187 N--VCRDVDECSRPRPVC-RNGTCENLPGAYLC--H---CDDGFKAGPNNDCVDVNECRE 238
+ C D DEC C R C N G++ C H C DG+ + CVD+NEC
Sbjct: 713 DGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVT 772
Query: 239 GGMVCRNG-RCRNTVGSFRC----ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
C G C NT+GSF C C PGY L DG C DVDEC H C C
Sbjct: 773 DLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL-KDG-ECEDVDECAMGTHTC--QPGFLC 828
Query: 294 TNTNGGYECS----CGAGW-KLVGRRCVDRDECKELPYVCAGG-ECRNFNGGYVCE---- 343
NT G + C C G+ + CVD +EC L C G C N G Y C+
Sbjct: 829 QNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPL 888
Query: 344 -CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERC 402
C G+ CVD +E E G HR C E G+ C
Sbjct: 889 ICARGYHASDDGXKCVD------VNECETG-VHR------------CGE----GQVCHNL 925
Query: 403 PAPDSAEFMRICQGGMGRPNLTQ---DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVL 459
P + C+ G R + D++EC P C NT GS+RC C G++L
Sbjct: 926 PGSYRCD----CKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLL 981
Query: 460 APDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRA 518
A DG C D +EC + + C C+N G Y+C C G+ D TC D+DECA+G
Sbjct: 982 AADGKRCEDVNEC--EAQRCSQ-ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAG 1038
Query: 519 -SCTFRCHNTAGSFRCTCP-YGYAVAADGVHCRDIDECVQEPRVCPHA--CENVVGSYIC 574
CTFRC N GS++C CP GY + A+G C+D+DEC C A C N+ GS+ C
Sbjct: 1039 ILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1098
Query: 575 ---KCPEGYRRTSAPQDSENACEDINECE 600
+CP Y + S + C D EC+
Sbjct: 1099 LRFECPPNYVQVSKTKCERTTCHDFLECQ 1127
Score = 252 bits (616), Expect = 5e-66
Identities = 180/552 (32%), Positives = 234/552 (42%), Gaps = 77/552 (13%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKP-GEYINPVTNETKPI 68
C VG Y C C G + C P G P E + V + T P+
Sbjct: 620 CINTVG----SYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPL 675
Query: 69 DECDIMPQLCKP-GTCHD---TPTGFQ-CGCDHGYEHDNTSHLCRDVDECSWGRPPCRGM 123
P CK G C T G C C GY C D DEC G C
Sbjct: 676 PLPQ--PNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRR 733
Query: 124 AQCVNLPGAFEC-----RCPPGYRLTPSLDECEDVDEC-GDQRICDHGD-CRNTIGSYRC 176
CVN G+F C C GY L + +C D++EC D C G+ C NT+GS+ C
Sbjct: 734 QFCVNTLGSFYCVNHTVLCADGYILN-AHRKCVDINECVTDLHTCSRGEHCVNTLGSFHC 792
Query: 177 ----ECKPGYTLRENVCRDVDECSRPRPVCRNG-TCENLPGAYLC----HCDDGFKAGPN 227
C+PGY L++ C DVDEC+ C+ G C+N G++ C C DGF P
Sbjct: 793 YKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPE 852
Query: 228 NDCVDVNECREGGMVCRNG-RCRNTVGSFRCE-----CAPGYTLTADGRNCRDVDECDEL 281
+CVD+NEC CR G C NTVGS+ C+ CA GY + DG C DV+EC+
Sbjct: 853 GNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGXKCVDVNECETG 912
Query: 282 PHPCGRDGNPSCTNTNGGYECSCGAGWK--LVGRRCVDRDECKELPYVCAGGECRNFNGG 339
H CG C N G Y C C AG++ GR C+D +EC P C N G
Sbjct: 913 VHRCGE--GQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGS 970
Query: 340 YVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYC 399
Y C C +G+ C D +E EA RC + +C C +G
Sbjct: 971 YRCSCASGFLLAADGKRCED------VNECEAQRCSQECANIYGSYQCYCRQG------- 1017
Query: 400 ERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPD-GYV 458
++ + G + D+DEC + RC+N GS++C CP+ GY
Sbjct: 1018 -----------YQLAEDG----HTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYT 1062
Query: 459 LAPDGLSCVDADECALDPRICGNG-TCSNTRGGYEC---QCSPGF-----TQGPDQTCVD 509
+ +G SC D DECAL C TC N +G + C +C P + T+ TC D
Sbjct: 1063 MTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHD 1122
Query: 510 VDECAEGRASCT 521
EC A T
Sbjct: 1123 FLECQNSPARIT 1134
Score = 232 bits (568), Expect = 3e-60
Identities = 164/512 (32%), Positives = 230/512 (44%), Gaps = 67/512 (13%)
Query: 151 EDVDECG--DQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGT 206
+D DEC +C H C NT+GSY C C PG++L+++ CR E P+P
Sbjct: 603 DDQDECLLLPGELCQHL-CINTVGSYHCACFPGFSLQDDGRTCRP--EGHPPQPEAPQEP 659
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLT 266
+ + N C D C++ C GS C C PGY +
Sbjct: 660 ALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQV--------CSTVGGSAICSCFPGYAIM 711
Query: 267 ADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC-----SCGAGWKL-VGRRCVDRDE 320
ADG +C D DEC H C R C NT G + C C G+ L R+CVD +E
Sbjct: 712 ADGVSCEDQDECLMGAHDCSR--RQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINE 769
Query: 321 CKELPYVCAGGE-CRNFNGGYVC----ECPAGWRFDKTAAVCVDERKELCYDEWEAGRCH 375
C + C+ GE C N G + C C G+ VDE C A H
Sbjct: 770 CVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDE----C-----AMGTH 820
Query: 376 RARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPD 435
+P L C ++G+ + + +RC F++ +G D++EC +
Sbjct: 821 TCQPGFL----CQNTKGSFYCQARQRC----MDGFLQDPEGN------CVDINECTSLSE 866
Query: 436 VC-VGGRCVNTDGSFRCE-----CPDGYVLAPDGLSCVDADECALDPRICGNG-TCSNTR 488
C G C+NT GS+ C+ C GY + DG CVD +EC CG G C N
Sbjct: 867 PCRPGFSCINTVGSYTCQRNPLICARGYHASDDGXKCVDVNECETGVHRCGEGQVCHNLP 926
Query: 489 GGYECQCSPGFTQGP-DQTCVDVDEC-AEGRASCTFRCHNTAGSFRCTCPYGYAVAADGV 546
G Y C C GF + + C+DV+EC A C C NT GS+RC+C G+ +AADG
Sbjct: 927 GSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGK 986
Query: 547 HCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLC 606
C D++EC E + C C N+ GSY C C +GY+ + + C DI+EC + +
Sbjct: 987 RCEDVNEC--EAQRCSQECANIYGSYQCYCRQGYQLA----EDGHTCTDIDECAQGAGIL 1040
Query: 607 SGGVCINTDGSFLCDC-DAGFEPSEDGTDCID 637
C+N GS+ C C + G+ + +G C D
Sbjct: 1041 CTFRCLNVPGSYQCACPEQGYTMTANGRSCKD 1072
Score = 230 bits (562), Expect = 2e-59
Identities = 195/644 (30%), Positives = 263/644 (40%), Gaps = 78/644 (12%)
Query: 5 EEDQSCAGAVGVPQTKYLC-CCSVG---HAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
E++ SC G+ K C CC +G A G CE+ P G P + + GE
Sbjct: 505 EDNDSC----GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLI 560
Query: 61 VTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD-VDECSWGRPP 119
V +P + P + + G E + + L D DEC P
Sbjct: 561 VPEVRRPPEPA------AAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLL-LPG 613
Query: 120 CRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECK 179
C+N G++ C C PG+ L C ++
Sbjct: 614 ELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTI 673
Query: 180 PGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECRE 238
P + N C+D C + C + G+ +C C G+ + C D +EC
Sbjct: 674 PLPLPQPNTCKDNGPCKQ--------VCSTVGGSAICSCFPGYAIMADGVSCEDQDECLM 725
Query: 239 GGMVC-RNGRCRNTVGSFRCE-----CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
G C R C NT+GSF C CA GY L A R C D++EC H C R +
Sbjct: 726 GAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAH-RKCVDINECVTDLHTCSRGEH-- 782
Query: 293 CTNTNGGYEC----SCGAGWKLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVCE---- 343
C NT G + C +C G+ L C D DEC + C G C+N G + C+
Sbjct: 783 CVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQR 842
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRY-CERC 402
C G+ D CVD + E P RP C G Y C+R
Sbjct: 843 CMDGFLQDPEGN-CVDINECTSLSE----------P---CRPGFSCINTV--GSYTCQRN 886
Query: 403 PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAP 461
P + + G D++EC C G+ C N GS+RC+C G+
Sbjct: 887 PLICARGYHASDDGXK-----CVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDA 941
Query: 462 DGLSCVDADECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRAS 519
G C+D +EC P R+C + TC NT G Y C C+ GF D + C DV+EC R
Sbjct: 942 FGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR-- 998
Query: 520 CTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRV-CPHACENVVGSYICKCPE 578
C+ C N GS++C C GY +A DG C DIDEC Q + C C NV GSY C CPE
Sbjct: 999 CSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPE 1058
Query: 579 -GYRRTSAPQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
GY T+ + +C+D++EC CS C N GSF C
Sbjct: 1059 QGYTMTA----NGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1098
Score = 162 bits (394), Expect = 4e-39
Identities = 134/443 (30%), Positives = 176/443 (39%), Gaps = 66/443 (14%)
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT-CSNTRGGYECQ-----C 495
C GS C C GY + DG+SC D DEC + C C NT G + C C
Sbjct: 693 CSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLC 752
Query: 496 SPGFTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFRC----TCPYGYAVAADGVHCR 549
+ G+ + CVD++EC +C+ C NT GSF C TC GYA+ DG C
Sbjct: 753 ADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK-DG-ECE 810
Query: 550 DIDECVQEPRVCPHA--CENVVGSYIC----KCPEGYRRTSAPQDSENACEDINECEEQE 603
D+DEC C C+N GS+ C +C +G+ QD E C DINEC
Sbjct: 811 DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFL-----QDPEGNCVDINECTSLS 865
Query: 604 DLCSGGV-CINTDGSFLCD-----CDAGFEPSEDGTDCID--------RRTG---TCYRS 646
+ C G CINT GS+ C C G+ S+DG C+D R G C+
Sbjct: 866 EPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGXKCVDVNECETGVHRCGEGQVCHNL 925
Query: 647 LVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECE---LCPAP 703
S RC+ + G + + C TLG+ + C L A
Sbjct: 926 PGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGS-YRCSCASGFLLAAD 984
Query: 704 GSPAR-LDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPG-LCA-- 759
G ++ C A + D+DECA G LC
Sbjct: 985 GKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFR 1044
Query: 760 ----PGRFRCVCGP-GYRPA--GEVCADVDECAVRPPPCDQL--CHNTDGSYDCL---CR 807
PG ++C C GY G C DVDECA+ C + CHN GS+ CL C
Sbjct: 1045 CLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECP 1104
Query: 808 TGY----ELDEDGANCRDVDECE 826
Y + + C D EC+
Sbjct: 1105 PNYVQVSKTKCERTTCHDFLECQ 1127
Score = 97.1 bits (231), Expect = 2e-19
Identities = 53/116 (45%), Positives = 64/116 (55%), Gaps = 13/116 (11%)
Query: 747 DVDECAAIPG-LCAP------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
DV+EC A PG LC G +RC C G+ A G+ C DV+EC + C Q C N
Sbjct: 948 DVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQECAN 1005
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTH-TCQQICSNTEGSYECSC-EDGY 851
GSY C CR GY+L EDG C D+DEC + C C N GSY+C+C E GY
Sbjct: 1006 IYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGY 1061
Score = 94.3 bits (224), Expect = 2e-18
Identities = 46/100 (46%), Positives = 55/100 (55%), Gaps = 5/100 (5%)
Query: 760 PGRFRCVCGPGY-RPA-GEVCADVDECAVRPPP-CDQLCHNTDGSYDCLCRTGYELDEDG 816
PG +RC C G+ R A G C DV+EC P C C NT GSY C C +G+ L DG
Sbjct: 926 PGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADG 985
Query: 817 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C DV+ECE C Q C+N GSY+C C GY+ D
Sbjct: 986 KRCEDVNECE--AQRCSQECANIYGSYQCYCRQGYQLAED 1023
Score = 87.0 bits (206), Expect = 3e-16
Identities = 47/124 (37%), Positives = 60/124 (48%), Gaps = 20/124 (16%)
Query: 747 DVDECAAIPGLCAPGRFRCV--------------CGPGYRPA--GEVCADVDECAVRPPP 790
D++EC ++ C PG F C+ C GY + G C DV+EC
Sbjct: 857 DINECTSLSEPCRPG-FSCINTVGSYTCQRNPLICARGYHASDDGXKCVDVNECETGVHR 915
Query: 791 CD--QLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC-ERDTHTCQQICSNTEGSYECSC 847
C Q+CHN GSY C C+ G++ D G C DV+EC CQ C NT GSY CSC
Sbjct: 916 CGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSC 975
Query: 848 EDGY 851
G+
Sbjct: 976 ASGF 979
Score = 85.4 bits (202), Expect = 8e-16
Identities = 52/138 (37%), Positives = 64/138 (46%), Gaps = 26/138 (18%)
Query: 747 DVDECAAIPGLCAPG--------------RFRCVCGPGYRPAGEVCADVDECAVRPPPCD 792
DVDECA C PG R RC+ G P G C D++EC PC
Sbjct: 811 DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCR 869
Query: 793 Q--LCHNTDGSYDC-----LCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSY 843
C NT GSY C +C GY +DG C DV+ECE H C Q+C N GSY
Sbjct: 870 PGFSCINTVGSYTCQRNPLICARGYHASDDGXKCVDVNECETGVHRCGEGQVCHNLPGSY 929
Query: 844 ECSCEDGYEKR--GDACV 859
C C+ G+++ G C+
Sbjct: 930 RCDCKAGFQRDAFGRGCI 947
Score = 69.3 bits (162), Expect = 5e-11
Identities = 43/109 (39%), Positives = 52/109 (47%), Gaps = 16/109 (14%)
Query: 765 CVCGPGYR--PAGEVCADVDECAVRPPPCD--QLCHNTDGSYDC-----LCRTGYELDED 815
C C PGY G C D DEC + C Q C NT GS+ C LC GY L+
Sbjct: 702 CSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAH 761
Query: 816 GANCRDVDECERDTHTCQ--QICSNTEGSYEC----SCEDGYEKRGDAC 858
C D++EC D HTC + C NT GS+ C +CE GY + C
Sbjct: 762 -RKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGEC 809
Score = 69.3 bits (162), Expect = 5e-11
Identities = 45/109 (41%), Positives = 54/109 (49%), Gaps = 20/109 (18%)
Query: 761 GRFRCV-----CGPGY-RPAGEVCADVDECAVRPPPCD--QLCHNTDGSYDCL----CRT 808
G F CV C GY A C D++EC C + C NT GS+ C C
Sbjct: 741 GSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEP 800
Query: 809 GYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECS----CEDGY 851
GY L +DG C DVDEC THTCQ +C NT+GS+ C C DG+
Sbjct: 801 GYAL-KDG-ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF 847
Score = 62.9 bits (146), Expect = 5e-09
Identities = 30/69 (43%), Positives = 35/69 (50%), Gaps = 7/69 (10%)
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC-- 845
PC Q+C GS C C GY + DG +C D DEC H C +Q C NT GS+ C
Sbjct: 688 PCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVN 747
Query: 846 ---SCEDGY 851
C DGY
Sbjct: 748 HTVLCADGY 756
Score = 48.8 bits (111), Expect = 8e-05
Identities = 21/42 (50%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 780 DVDECAVRPPP-CDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
D DEC + P C LC NT GSY C C G+ L +DG CR
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCR 645
Score = 48.0 bits (109), Expect = 1e-04
Identities = 38/131 (29%), Positives = 50/131 (38%), Gaps = 15/131 (11%)
Query: 509 DVDECAEGRAS-CTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN 567
D DEC C C NT GS+ C C G+++ DG CR Q P E
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPE--APQ--EP 659
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
+ S + PQ N C+D C++ VC GS +C C G+
Sbjct: 660 ALKSEFSQVASNTIPLPLPQ--PNTCKDNGPCKQ--------VCSTVGGSAICSCFPGYA 709
Query: 628 PSEDGTDCIDR 638
DG C D+
Sbjct: 710 IMADGVSCEDQ 720
Score = 36.7 bits (81), Expect = 0.35
Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 821 DVDECER-DTHTCQQICSNTEGSYECSCEDGYEKRGD 856
D DEC CQ +C NT GSY C+C G+ + D
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDD 640
Score = 34.3 bits (75), Expect = 1.9
Identities = 32/119 (26%), Positives = 43/119 (36%), Gaps = 18/119 (15%)
Query: 747 DVDECAAIPG-----LC--APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHN 797
D DEC +PG LC G + C C PG+ + G C P + +
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
+ + L N C +D C+Q+CS GS CSC GY D
Sbjct: 664 ---EFSQVASNTIPLPLPQPNT-----C-KDNGPCKQVCSTVGGSAICSCFPGYAIMAD 713
>AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein.
Length = 1231
Score = 249 bits (609), Expect = 4e-65
Identities = 188/569 (33%), Positives = 244/569 (42%), Gaps = 84/569 (14%)
Query: 69 DECDIMP-QLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
DEC ++P +LC+ C +T + C C G+ + CR G PP Q
Sbjct: 606 DECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPE-----GHPPQPEAPQEP 659
Query: 128 NLPGAFECRCPPGYRL-TPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
L F L P + C+D C +++C GS C C PGY +
Sbjct: 660 ALKSEFSQVASNTIPLPLPQPNTCKDNGPC--KQVCS-----TVGGSAICSCFPGYAIMA 712
Query: 187 N--VCRDVDECSRPRPVC-RNGTCENLPGAYLC--H---CDDGFKAGPNNDCVDVNECRE 238
+ C D DEC C R C N G++ C H C DG+ + CV NEC
Sbjct: 713 DGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVGKNECVT 772
Query: 239 GGMVCRNG-RCRNTVGSFRC----ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
C G C NT+GSF C C PGY L DG C DVDEC H C C
Sbjct: 773 DLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL-KDG-ECEDVDECAMGTHTC--QPGFLC 828
Query: 294 TNTNGGYECS----CGAGW-KLVGRRCVDRDECKELPYVCAGG-ECRNFNGGYVCE---- 343
NT G + C C G+ + CVD +EC L C G C N G Y C+
Sbjct: 829 QNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPL 888
Query: 344 -CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERC 402
C G+ A CVD +E E G HR C E G+ C
Sbjct: 889 ICARGYHASDDGAKCVD------VNECETG-VHR------------CGE----GQVCHNL 925
Query: 403 PAPDSAEFMRICQGGMGRPNLTQ---DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVL 459
P + C+ G R + D++EC P C NT GS+RC C G++L
Sbjct: 926 PGSYRCD----CKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLL 981
Query: 460 APDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRA 518
A DG C D +EC + + C C+N G Y+C C G+ D TC D+DECA+G
Sbjct: 982 AADGKRCEDVNEC--EAQRCSQ-ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAG 1038
Query: 519 -SCTFRCHNTAGSFRCTCP-YGYAVAADGVHCRDIDECVQEPRVCPHA--CENVVGSYIC 574
CTFRC N GS++C CP GY + A+G C+D+DEC C A C N+ GS+ C
Sbjct: 1039 ILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1098
Query: 575 ---KCPEGYRRTSAPQDSENACEDINECE 600
+CP Y + S + C D EC+
Sbjct: 1099 LRFECPPNYVQVSKTKCERTTCHDFLECQ 1127
Score = 247 bits (604), Expect = 1e-64
Identities = 179/552 (32%), Positives = 232/552 (42%), Gaps = 77/552 (13%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKP-GEYINPVTNETKPI 68
C VG Y C C G + C P G P E + V + T P+
Sbjct: 620 CINTVG----SYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPL 675
Query: 69 DECDIMPQLCKP-GTCHD---TPTGFQ-CGCDHGYEHDNTSHLCRDVDECSWGRPPCRGM 123
P CK G C T G C C GY C D DEC G C
Sbjct: 676 PLPQ--PNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRR 733
Query: 124 AQCVNLPGAFEC-----RCPPGYRLTPSLDECEDVDEC-GDQRICDHGD-CRNTIGSYRC 176
CVN G+F C C GY L + +C +EC D C G+ C NT+GS+ C
Sbjct: 734 QFCVNTLGSFYCVNHTVLCADGYILN-AHRKCVGKNECVTDLHTCSRGEHCVNTLGSFHC 792
Query: 177 ----ECKPGYTLRENVCRDVDECSRPRPVCRNG-TCENLPGAYLC----HCDDGFKAGPN 227
C+PGY L++ C DVDEC+ C+ G C+N G++ C C DGF P
Sbjct: 793 YKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPE 852
Query: 228 NDCVDVNECREGGMVCRNG-RCRNTVGSFRCE-----CAPGYTLTADGRNCRDVDECDEL 281
+CVD+NEC CR G C NTVGS+ C+ CA GY + DG C DV+EC+
Sbjct: 853 GNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETG 912
Query: 282 PHPCGRDGNPSCTNTNGGYECSCGAGWK--LVGRRCVDRDECKELPYVCAGGECRNFNGG 339
H CG C N G Y C C AG++ GR C+D +EC P C N G
Sbjct: 913 VHRCGE--GQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGS 970
Query: 340 YVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYC 399
Y C C +G+ C D +E EA RC + +C C +G
Sbjct: 971 YRCSCASGFLLAADGKRCED------VNECEAQRCSQECANIYGSYQCYCRQG------- 1017
Query: 400 ERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPD-GYV 458
++ + G + D+DEC + RC+N GS++C CP+ GY
Sbjct: 1018 -----------YQLAEDG----HTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYT 1062
Query: 459 LAPDGLSCVDADECALDPRICGNG-TCSNTRGGYEC---QCSPGF-----TQGPDQTCVD 509
+ +G SC D DECAL C TC N +G + C +C P + T+ TC D
Sbjct: 1063 MTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHD 1122
Query: 510 VDECAEGRASCT 521
EC A T
Sbjct: 1123 FLECQNSPARIT 1134
Score = 231 bits (566), Expect = 6e-60
Identities = 163/512 (31%), Positives = 230/512 (44%), Gaps = 67/512 (13%)
Query: 151 EDVDECG--DQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGT 206
+D DEC +C H C NT+GSY C C PG++L+++ CR E P+P
Sbjct: 603 DDQDECLLLPGELCQHL-CINTVGSYHCACFPGFSLQDDGRTCRP--EGHPPQPEAPQEP 659
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLT 266
+ + N C D C++ C GS C C PGY +
Sbjct: 660 ALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQV--------CSTVGGSAICSCFPGYAIM 711
Query: 267 ADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC-----SCGAGWKL-VGRRCVDRDE 320
ADG +C D DEC H C R C NT G + C C G+ L R+CV ++E
Sbjct: 712 ADGVSCEDQDECLMGAHDCSR--RQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVGKNE 769
Query: 321 CKELPYVCAGGE-CRNFNGGYVC----ECPAGWRFDKTAAVCVDERKELCYDEWEAGRCH 375
C + C+ GE C N G + C C G+ VDE C A H
Sbjct: 770 CVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDE----C-----AMGTH 820
Query: 376 RARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPD 435
+P L C ++G+ + + +RC F++ +G D++EC +
Sbjct: 821 TCQPGFL----CQNTKGSFYCQARQRC----MDGFLQDPEGN------CVDINECTSLSE 866
Query: 436 VC-VGGRCVNTDGSFRCE-----CPDGYVLAPDGLSCVDADECALDPRICGNG-TCSNTR 488
C G C+NT GS+ C+ C GY + DG CVD +EC CG G C N
Sbjct: 867 PCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLP 926
Query: 489 GGYECQCSPGFTQGP-DQTCVDVDEC-AEGRASCTFRCHNTAGSFRCTCPYGYAVAADGV 546
G Y C C GF + + C+DV+EC A C C NT GS+RC+C G+ +AADG
Sbjct: 927 GSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGK 986
Query: 547 HCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLC 606
C D++EC E + C C N+ GSY C C +GY+ + + C DI+EC + +
Sbjct: 987 RCEDVNEC--EAQRCSQECANIYGSYQCYCRQGYQLA----EDGHTCTDIDECAQGAGIL 1040
Query: 607 SGGVCINTDGSFLCDC-DAGFEPSEDGTDCID 637
C+N GS+ C C + G+ + +G C D
Sbjct: 1041 CTFRCLNVPGSYQCACPEQGYTMTANGRSCKD 1072
Score = 225 bits (551), Expect = 4e-58
Identities = 194/644 (30%), Positives = 261/644 (40%), Gaps = 78/644 (12%)
Query: 5 EEDQSCAGAVGVPQTKYLC-CCSVG---HAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
E++ SC G+ K C CC +G A G CE+ P G P + + GE
Sbjct: 505 EDNDSC----GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLI 560
Query: 61 VTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD-VDECSWGRPP 119
V +P + P + + G E + + L D DEC P
Sbjct: 561 VPEVRRPPEPA------AAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLL-LPG 613
Query: 120 CRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECK 179
C+N G++ C C PG+ L C ++
Sbjct: 614 ELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTI 673
Query: 180 PGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECRE 238
P + N C+D C + C + G+ +C C G+ + C D +EC
Sbjct: 674 PLPLPQPNTCKDNGPCKQ--------VCSTVGGSAICSCFPGYAIMADGVSCEDQDECLM 725
Query: 239 GGMVC-RNGRCRNTVGSFRCE-----CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
G C R C NT+GSF C CA GY L A R C +EC H C R +
Sbjct: 726 GAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAH-RKCVGKNECVTDLHTCSRGEH-- 782
Query: 293 CTNTNGGYEC----SCGAGWKLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVCE---- 343
C NT G + C +C G+ L C D DEC + C G C+N G + C+
Sbjct: 783 CVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQR 842
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRY-CERC 402
C G+ D CVD + E P RP C G Y C+R
Sbjct: 843 CMDGFLQDPEGN-CVDINECTSLSE----------P---CRPGFSCINTV--GSYTCQRN 886
Query: 403 PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAP 461
P + + G D++EC C G+ C N GS+RC+C G+
Sbjct: 887 PLICARGYHASDDGAK-----CVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDA 941
Query: 462 DGLSCVDADECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRAS 519
G C+D +EC P R+C + TC NT G Y C C+ GF D + C DV+EC R
Sbjct: 942 FGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR-- 998
Query: 520 CTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRV-CPHACENVVGSYICKCPE 578
C+ C N GS++C C GY +A DG C DIDEC Q + C C NV GSY C CPE
Sbjct: 999 CSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPE 1058
Query: 579 -GYRRTSAPQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
GY T+ + +C+D++EC CS C N GSF C
Sbjct: 1059 QGYTMTA----NGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1098
Score = 157 bits (382), Expect = 1e-37
Identities = 133/443 (30%), Positives = 174/443 (39%), Gaps = 66/443 (14%)
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT-CSNTRGGYECQ-----C 495
C GS C C GY + DG+SC D DEC + C C NT G + C C
Sbjct: 693 CSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLC 752
Query: 496 SPGFTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFRC----TCPYGYAVAADGVHCR 549
+ G+ + CV +EC +C+ C NT GSF C TC GYA+ DG C
Sbjct: 753 ADGYILNAHRKCVGKNECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK-DG-ECE 810
Query: 550 DIDECVQEPRVCPHA--CENVVGSYIC----KCPEGYRRTSAPQDSENACEDINECEEQE 603
D+DEC C C+N GS+ C +C +G+ QD E C DINEC
Sbjct: 811 DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFL-----QDPEGNCVDINECTSLS 865
Query: 604 DLCSGGV-CINTDGSFLCD-----CDAGFEPSEDGTDCID--------RRTG---TCYRS 646
+ C G CINT GS+ C C G+ S+DG C+D R G C+
Sbjct: 866 EPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNL 925
Query: 647 LVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECE---LCPAP 703
S RC+ + G + + C TLG+ + C L A
Sbjct: 926 PGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGS-YRCSCASGFLLAAD 984
Query: 704 GSPAR-LDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPG-LCA-- 759
G ++ C A + D+DECA G LC
Sbjct: 985 GKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFR 1044
Query: 760 ----PGRFRCVCGP-GYRPA--GEVCADVDECAVRPPPCDQL--CHNTDGSYDCL---CR 807
PG ++C C GY G C DVDECA+ C + CHN GS+ CL C
Sbjct: 1045 CLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECP 1104
Query: 808 TGY----ELDEDGANCRDVDECE 826
Y + + C D EC+
Sbjct: 1105 PNYVQVSKTKCERTTCHDFLECQ 1127
Score = 97.1 bits (231), Expect = 2e-19
Identities = 53/116 (45%), Positives = 64/116 (55%), Gaps = 13/116 (11%)
Query: 747 DVDECAAIPG-LCAP------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
DV+EC A PG LC G +RC C G+ A G+ C DV+EC + C Q C N
Sbjct: 948 DVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQECAN 1005
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTH-TCQQICSNTEGSYECSC-EDGY 851
GSY C CR GY+L EDG C D+DEC + C C N GSY+C+C E GY
Sbjct: 1006 IYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGY 1061
Score = 94.3 bits (224), Expect = 2e-18
Identities = 46/100 (46%), Positives = 55/100 (55%), Gaps = 5/100 (5%)
Query: 760 PGRFRCVCGPGY-RPA-GEVCADVDECAVRPPP-CDQLCHNTDGSYDCLCRTGYELDEDG 816
PG +RC C G+ R A G C DV+EC P C C NT GSY C C +G+ L DG
Sbjct: 926 PGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADG 985
Query: 817 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C DV+ECE C Q C+N GSY+C C GY+ D
Sbjct: 986 KRCEDVNECE--AQRCSQECANIYGSYQCYCRQGYQLAED 1023
Score = 87.0 bits (206), Expect = 3e-16
Identities = 53/138 (38%), Positives = 65/138 (47%), Gaps = 26/138 (18%)
Query: 747 DVDECAAIPGLCAPG--------------RFRCVCGPGYRPAGEVCADVDECAVRPPPCD 792
DVDECA C PG R RC+ G P G C D++EC PC
Sbjct: 811 DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCR 869
Query: 793 Q--LCHNTDGSYDC-----LCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSY 843
C NT GSY C +C GY +DGA C DV+ECE H C Q+C N GSY
Sbjct: 870 PGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSY 929
Query: 844 ECSCEDGYEKR--GDACV 859
C C+ G+++ G C+
Sbjct: 930 RCDCKAGFQRDAFGRGCI 947
Score = 87.0 bits (206), Expect = 3e-16
Identities = 47/124 (37%), Positives = 60/124 (48%), Gaps = 20/124 (16%)
Query: 747 DVDECAAIPGLCAPGRFRCV--------------CGPGYRPA--GEVCADVDECAVRPPP 790
D++EC ++ C PG F C+ C GY + G C DV+EC
Sbjct: 857 DINECTSLSEPCRPG-FSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHR 915
Query: 791 CD--QLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC-ERDTHTCQQICSNTEGSYECSC 847
C Q+CHN GSY C C+ G++ D G C DV+EC CQ C NT GSY CSC
Sbjct: 916 CGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSC 975
Query: 848 EDGY 851
G+
Sbjct: 976 ASGF 979
Score = 64.5 bits (150), Expect = 2e-09
Identities = 42/109 (38%), Positives = 50/109 (45%), Gaps = 16/109 (14%)
Query: 765 CVCGPGYR--PAGEVCADVDECAVRPPPCD--QLCHNTDGSYDC-----LCRTGYELDED 815
C C PGY G C D DEC + C Q C NT GS+ C LC GY L+
Sbjct: 702 CSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAH 761
Query: 816 GANCRDVDECERDTHTCQ--QICSNTEGSYEC----SCEDGYEKRGDAC 858
C +EC D HTC + C NT GS+ C +CE GY + C
Sbjct: 762 -RKCVGKNECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGEC 809
Score = 64.5 bits (150), Expect = 2e-09
Identities = 44/109 (40%), Positives = 52/109 (47%), Gaps = 20/109 (18%)
Query: 761 GRFRCV-----CGPGY-RPAGEVCADVDECAVRPPPCD--QLCHNTDGSYDCL----CRT 808
G F CV C GY A C +EC C + C NT GS+ C C
Sbjct: 741 GSFYCVNHTVLCADGYILNAHRKCVGKNECVTDLHTCSRGEHCVNTLGSFHCYKALTCEP 800
Query: 809 GYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECS----CEDGY 851
GY L +DG C DVDEC THTCQ +C NT+GS+ C C DG+
Sbjct: 801 GYAL-KDG-ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF 847
Score = 63.3 bits (147), Expect = 4e-09
Identities = 33/79 (41%), Positives = 38/79 (48%), Gaps = 8/79 (10%)
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC-- 845
PC Q+C GS C C GY + DG +C D DEC H C +Q C NT GS+ C
Sbjct: 688 PCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVN 747
Query: 846 ---SCEDGYEKRGD-ACVG 860
C DGY CVG
Sbjct: 748 HTVLCADGYILNAHRKCVG 766
Score = 48.8 bits (111), Expect = 8e-05
Identities = 21/42 (50%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 780 DVDECAVRPPP-CDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
D DEC + P C LC NT GSY C C G+ L +DG CR
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCR 645
Score = 48.0 bits (109), Expect = 1e-04
Identities = 38/131 (29%), Positives = 50/131 (38%), Gaps = 15/131 (11%)
Query: 509 DVDECAEGRAS-CTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN 567
D DEC C C NT GS+ C C G+++ DG CR Q P E
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPE--APQ--EP 659
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
+ S + PQ N C+D C++ VC GS +C C G+
Sbjct: 660 ALKSEFSQVASNTIPLPLPQ--PNTCKDNGPCKQ--------VCSTVGGSAICSCFPGYA 709
Query: 628 PSEDGTDCIDR 638
DG C D+
Sbjct: 710 IMADGVSCEDQ 720
Score = 36.7 bits (81), Expect = 0.35
Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 821 DVDECER-DTHTCQQICSNTEGSYECSCEDGYEKRGD 856
D DEC CQ +C NT GSY C+C G+ + D
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDD 640
Score = 34.3 bits (75), Expect = 1.9
Identities = 32/119 (26%), Positives = 43/119 (36%), Gaps = 18/119 (15%)
Query: 747 DVDECAAIPG-----LC--APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHN 797
D DEC +PG LC G + C C PG+ + G C P + +
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
+ + L N C +D C+Q+CS GS CSC GY D
Sbjct: 664 ---EFSQVASNTIPLPLPQPNT-----C-KDNGPCKQVCSTVGGSAICSCFPGYAIMAD 713
>AL117551-1|CAB55988.1| 511|Homo sapiens hypothetical protein
protein.
Length = 511
Score = 243 bits (594), Expect = 2e-63
Identities = 135/335 (40%), Positives = 171/335 (51%), Gaps = 33/335 (9%)
Query: 242 VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPC-GRDGNPSCTNTNGGY 300
VC NG C NT GSF+C+C GY L+ D +C D+DECD P C G D C NTNG Y
Sbjct: 2 VCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECD-FPAACIGGD----CINTNGSY 56
Query: 301 ECSCGAGWKLV-GRRCVDRDECKELPYVC-AGGECRNFNGGYVCECPAGWRFDKTAAVCV 358
C C G +LV GR+C D DEC + P +C G C+N G YVC C G+ + C
Sbjct: 57 RCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCE 116
Query: 359 D----ERKELCYDEW-EAGRCHRARPLQLARPECCCSEGAAWGRYCE--RCPAPDSAEFM 411
+ K+ CY + + C + + ECCCS GA WG +CE CP SAEF
Sbjct: 117 EVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFH 176
Query: 412 RICQGGMGRP---NLT-------QDLDECRV-RPDVCVGGRCVNTDGSFRCECPDGYVLA 460
+C G G N+ +D+DEC + ++C G+CVNT + C C G+
Sbjct: 177 SLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYD 236
Query: 461 PDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQ-TC-----VDVDECA 514
+ L CVD DEC LD C NG C NTRGGY C C+P P Q C +DVDEC
Sbjct: 237 GNLLECVDVDEC-LDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQ 295
Query: 515 EGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR 549
+ A RC N GS+RC C + G C+
Sbjct: 296 DPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQ 330
Score = 202 bits (493), Expect = 4e-51
Identities = 156/507 (30%), Positives = 217/507 (42%), Gaps = 75/507 (14%)
Query: 55 GEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS 114
G +++ + + IDECD P C G C +T ++C C G+ C+D+DECS
Sbjct: 22 GYHLSRDRSHCEDIDECDF-PAACIGGDCINTNGSYRCLCPQGHRLVG-GRKCQDIDECS 79
Query: 115 WGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSY 174
C C NL G++ C C G+ T CE+V++ ++ C N +
Sbjct: 80 QDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKEC----YLNFDDTV 135
Query: 175 RCECKPGYTLRENVCRDVDECSRPR---PVCRNGTCENLPGA-YLCHCDDGFKAGPNNDC 230
C+ L NV + CS C C A + C DG +N+
Sbjct: 136 FCDS----VLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNI 191
Query: 231 V--------DVNECRE-GGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDEL 281
V D++EC G +C+ G+C NT + C C G+ + C DVDEC L
Sbjct: 192 VNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDEC--L 249
Query: 282 PHPCGRDGNPSCTNTNGGYECSCG--AGWKLVGRRCV-----DRDECKELPYVCAGGECR 334
R+G C NT GGY C+C A + R+C+ D DEC++ P C G C
Sbjct: 250 DESNCRNG--VCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQD-PAACRPGRCV 306
Query: 335 NFNGGYVCECPAGW---------RFDKTAAVCVDERKELCYDE-WEAGRCHRARPLQ--- 381
N G Y CEC W + ++ A ER+++C+ + E G C A PL
Sbjct: 307 NLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMC--AGPLAGPA 364
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG-----------MGRP-----NLTQ 425
L +CCC +G WG C CP + Q +G+P + +
Sbjct: 365 LTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEE 424
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC-ALDPR--ICGNG 482
D DECR CV GRCV G CECP G+ L CVD DEC L+ R +C +
Sbjct: 425 DSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSE 479
Query: 483 TCSNTRGGYECQCSPGFTQG-PDQTCV 508
C NT G + C C GF + P CV
Sbjct: 480 RCVNTSGSFRCVCKAGFARSRPHGACV 506
Score = 200 bits (489), Expect = 1e-50
Identities = 167/542 (30%), Positives = 224/542 (41%), Gaps = 68/542 (12%)
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL- 184
C N PG+F+C+C GY L+ CED+DEC C GDC NT GSYRC C G+ L
Sbjct: 8 CSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLV 67
Query: 185 RENVCRDVDECSRPRPVC-RNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC 243
C+D+DECS+ +C +G C+NL G+Y+C CD+GF P D + C E
Sbjct: 68 GGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFT--PTQ---DQHGCEEVEQPH 122
Query: 244 RNGRC-RNTVGSFRCECAPGYTLTADGRNCR----DVDECDELPHP--CGRDGNPSCTNT 296
C N + C+ +T C D C+ P P + + C +
Sbjct: 123 HKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDG 182
Query: 297 NGGYECSCGAGWKLVGRRCVDRDECKEL-PYVCAGGECRNFNGGYVCECPAGWRFDKTAA 355
G + + + + R D DEC +C G+C N GY C C G+ +D
Sbjct: 183 KGYTQDNNIVNYGIPAHR--DIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLL 240
Query: 356 VCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQ 415
CVD + L G C R C C+ A + +C +P+
Sbjct: 241 ECVDVDECLDESNCRNGVCENTR----GGYRCACTPPAEYSPAQRQCLSPEE-------- 288
Query: 416 GGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
D+DEC+ P C GRCVN GS+RCEC +V P G C E +
Sbjct: 289 ---------MDVDECQ-DPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDC-QLPESPAE 337
Query: 476 PRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGR---ASCTFRCHNTAGSFR 532
C + R G + C+ G GP T D C +GR A C AGS
Sbjct: 338 RAPERRDVCWSQR-GEDGMCA-GPLAGPALTFDDCC-CRQGRGWGAQCRPCPPRGAGSH- 393
Query: 533 CTCPYGYAVAAD---------GVHCRDID---ECVQEPRVCPHACENVVGSYICKCPEGY 580
CP + + G RD D E E R C G +C+CP G+
Sbjct: 394 --CPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGF 451
Query: 581 RRTSAPQDSENACEDINECEEQED---LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
+ + S C DI+EC E LC C+NT GSF C C AGF S C+
Sbjct: 452 QLDA----SRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVP 507
Query: 638 RR 639
+R
Sbjct: 508 QR 509
Score = 177 bits (432), Expect = 1e-43
Identities = 148/508 (29%), Positives = 204/508 (40%), Gaps = 56/508 (11%)
Query: 77 LCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECR 136
+C G C +TP FQC C GY C D+DEC + C G C+N G++ C
Sbjct: 2 VCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDF-PAACIG-GDCINTNGSYRCL 59
Query: 137 CPPGYRLTPSLDECEDVDECG-DQRIC-DHGDCRNTIGSYRCECKPGYTLRENV--CRDV 192
CP G+RL +C+D+DEC D +C HG C+N GSY C C G+T ++ C +V
Sbjct: 60 CPQGHRLVGG-RKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEV 118
Query: 193 DECSRPRPVCRNGT----CENLPGAYLC--HCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
++ + N C+++ + C AG + C ++ C +
Sbjct: 119 EQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHC-EIYPCPVYSSAEFHS 177
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
C + G + Y + A RD+DEC ++G C NT GYEC C
Sbjct: 178 LCPDGKGYTQDNNIVNYGIPAH----RDIDECMLFGSEICKEG--KCVNTQPGYECYCKQ 231
Query: 307 GWKLVGR--RCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKEL 364
G+ G CVD DEC + C G C N GGY C C + C+ +E+
Sbjct: 232 GFYYDGNLLECVDVDECLD-ESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSP-EEM 289
Query: 365 CYDE-WEAGRCHRARPLQL-ARPECCCSEGAAWGRYCERCPAPDS----AEFMR------ 412
DE + C R + L C C G C P+S A R
Sbjct: 290 DVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQ 349
Query: 413 -----ICQGGMGRPNLTQD----------LDECRVRPDVCVGGRCVNTDGSFRCECPDGY 457
+C G + P LT D +CR P G C +
Sbjct: 350 RGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSP 409
Query: 458 VLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAE- 515
+L D+ E D C +G C GG C+C GF + CVD+DEC E
Sbjct: 410 LLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECREL 469
Query: 516 ---GRASCTFRCHNTAGSFRCTCPYGYA 540
G + RC NT+GSFRC C G+A
Sbjct: 470 NQRGLLCKSERCVNTSGSFRCVCKAGFA 497
Score = 159 bits (385), Expect = 5e-38
Identities = 123/386 (31%), Positives = 167/386 (43%), Gaps = 45/386 (11%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCEA--CPPRGSPAHTALCGEKPG-EYINPVTNETK 66
C + T+ CCCS+G WG CE CP S +LC + G N + N
Sbjct: 137 CDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGI 196
Query: 67 P----IDECDIM-PQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
P IDEC + ++CK G C +T G++C C G+ +D C DVDEC CR
Sbjct: 197 PAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDEC-LDESNCR 255
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDEC-----EDVDECGDQRICDHGDCRNTIGSYRC 176
C N G + C C P +P+ +C DVDEC D C G C N GSYRC
Sbjct: 256 N-GVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRC 314
Query: 177 ECKPGYTLRENVCRD--VDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGP-NNDCVDV 233
EC+P + + RD + E R R C + G +DG AGP +
Sbjct: 315 ECRPPWVPGPS-GRDCQLPESPAERAPERRDVCWSQRG------EDGMCAGPLAGPALTF 367
Query: 234 NE--CREG---GMVCRNGRCRNTVGSFRCECAP----GYTLTAD---GRNCRDVDECDEL 281
++ CR+G G CR C C + + T+ G+ RD D +E
Sbjct: 368 DDCCCRQGRGWGAQCR--PCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEED 425
Query: 282 PHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKEL---PYVCAGGECRNF 336
C R + C GG C C G++L RCVD DEC+EL +C C N
Sbjct: 426 SDEC-RCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNT 484
Query: 337 NGGYVCECPAGWRFDKTAAVCVDERK 362
+G + C C AG+ + CV +R+
Sbjct: 485 SGSFRCVCKAGFARSRPHGACVPQRR 510
Score = 153 bits (372), Expect = 2e-36
Identities = 108/343 (31%), Positives = 140/343 (40%), Gaps = 53/343 (15%)
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRR 582
C NT GSF+C C GY ++ D HC DIDEC P C C N GSY C CP+G+R
Sbjct: 8 CSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGDCINTNGSYRCLCPQGHRL 66
Query: 583 TSAPQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTG 641
+ C+DI+EC + LC G C N GS++C CD GF P++D C +
Sbjct: 67 VGGRK-----CQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVE-- 119
Query: 642 TCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCP 701
+P +VT+ +CCC+LGA WG CE+ P
Sbjct: 120 -----------QPHHKKECYLNFDDTVFCDSVLAT--NVTQQECCCSLGAGWGDHCEIYP 166
Query: 702 APG-SPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIPG-LCA 759
P S A +L P + D+DEC +C
Sbjct: 167 CPVYSSAEFH-----SLCPDGKGYTQDNNIVNYG-------IPAHRDIDECMLFGSEICK 214
Query: 760 PGR-------FRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
G+ + C C G+ G + C DVDEC + +C NT G Y C C
Sbjct: 215 EGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPA 274
Query: 811 ELDEDGANC-----RDVDECERDTHTCQQ-ICSNTEGSYECSC 847
E C DVDEC+ D C+ C N GSY C C
Sbjct: 275 EYSPAQRQCLSPEEMDVDECQ-DPAACRPGRCVNLPGSYRCEC 316
Score = 111 bits (267), Expect = 1e-23
Identities = 85/323 (26%), Positives = 119/323 (36%), Gaps = 30/323 (9%)
Query: 509 DVDECAE-GRASCTF-RCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
D+DEC G C +C NT + C C G+ + + C D+DEC+ E CE
Sbjct: 201 DIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCE 260
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
N G Y C C + A + + E D++EC++ C G C+N GS+ C+C
Sbjct: 261 NTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPA-ACRPGRCVNLPGSYRCECRPP 319
Query: 626 FEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGH-VTKAQ 684
+ P G DC L E G +T
Sbjct: 320 WVPGPSGRDC----------QLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDD 369
Query: 685 CCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDV 744
CCC G WG++C CP G+ + C T
Sbjct: 370 CCCRQGRGWGAQCRPCPPRGAGSH---CP----TSQSESNSFWDTSPLLLGKPPRDEDSS 422
Query: 745 FADVDECAAIPGLCAP--GRFRCVCGPGYR--PAGEVCADVDECAV---RPPPC-DQLCH 796
D DEC + G C P G C C G++ + C D+DEC R C + C
Sbjct: 423 EEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCV 482
Query: 797 NTDGSYDCLCRTGYELDEDGANC 819
NT GS+ C+C+ G+ C
Sbjct: 483 NTSGSFRCVCKAGFARSRPHGAC 505
Score = 102 bits (245), Expect = 5e-21
Identities = 47/121 (38%), Positives = 61/121 (50%), Gaps = 3/121 (2%)
Query: 435 DVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQ 494
DVC G C NT GSF+C+C GY L+ D C D DEC P C G C NT G Y C
Sbjct: 1 DVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDF-PAACIGGDCINTNGSYRCL 59
Query: 495 CSPGFTQGPDQTCVDVDECAEGRASCT--FRCHNTAGSFRCTCPYGYAVAADGVHCRDID 552
C G + C D+DEC++ + C C N GS+ C C G+ D C +++
Sbjct: 60 CPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVE 119
Query: 553 E 553
+
Sbjct: 120 Q 120
Score = 85.0 bits (201), Expect = 1e-15
Identities = 42/107 (39%), Positives = 57/107 (53%), Gaps = 7/107 (6%)
Query: 756 GLCA--PGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYE 811
G+C+ PG F+C C GY + + C D+DEC C NT+GSY CLC G+
Sbjct: 6 GICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHR 65
Query: 812 LDEDGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGD 856
L G C+D+DEC +D C C N +GSY C C++G+ D
Sbjct: 66 L-VGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQD 111
Score = 82.6 bits (195), Expect = 5e-15
Identities = 49/150 (32%), Positives = 66/150 (44%), Gaps = 11/150 (7%)
Query: 3 WNE--EDQSCAGAVGVPQTKYL-CCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEY-- 57
W++ ED CAG + P + CCC G WGA C CPPRG+ +H + +
Sbjct: 347 WSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWD 406
Query: 58 INPVTNETKPIDEC----DIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDEC 113
+P+ P DE D C G C P G C C G++ D + C D+DEC
Sbjct: 407 TSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDEC 466
Query: 114 SW--GRPPCRGMAQCVNLPGAFECRCPPGY 141
R +CVN G+F C C G+
Sbjct: 467 RELNQRGLLCKSERCVNTSGSFRCVCKAGF 496
Score = 68.1 bits (159), Expect = 1e-10
Identities = 28/66 (42%), Positives = 36/66 (54%), Gaps = 1/66 (1%)
Query: 791 CDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCED 849
CD +C NT GS+ C C +GY L D ++C D+DEC+ C NT GSY C C
Sbjct: 3 CDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQ 62
Query: 850 GYEKRG 855
G+ G
Sbjct: 63 GHRLVG 68
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/130 (34%), Positives = 58/130 (44%), Gaps = 19/130 (14%)
Query: 747 DVDEC----AAIPGLC--APGRFRCVCGPGYR-PAGEVCADVDECAVRPPPC--DQLCHN 797
D+DEC A I G C G +RC+C G+R G C D+DEC+ P C C N
Sbjct: 34 DIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKN 93
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVD------ECE---RDTHTCQQICSNTEGSYECSCE 848
GSY C+C G+ +D C +V+ EC DT C + + EC C
Sbjct: 94 LQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCS 153
Query: 849 DGYEKRGDAC 858
G GD C
Sbjct: 154 LG-AGWGDHC 162
Score = 47.2 bits (107), Expect = 2e-04
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDEC----ERDTHTCQQICSNTEGSYECSCEDG 850
C G C C G++LD A C D+DEC +R + C NT GS+ C C+ G
Sbjct: 436 CVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAG 495
Query: 851 YEK 853
+ +
Sbjct: 496 FAR 498
Score = 43.6 bits (98), Expect = 0.003
Identities = 32/89 (35%), Positives = 39/89 (43%), Gaps = 11/89 (12%)
Query: 742 LDVFADVDECAAIPGLC--APGRFRCVCGPG--YRPAGEVCA-----DVDECAVRPPPCD 792
+DV +DE G+C G +RC C P Y PA C DVDEC P C
Sbjct: 243 VDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQ-DPAACR 301
Query: 793 Q-LCHNTDGSYDCLCRTGYELDEDGANCR 820
C N GSY C CR + G +C+
Sbjct: 302 PGRCVNLPGSYRCECRPPWVPGPSGRDCQ 330
Score = 43.2 bits (97), Expect = 0.004
Identities = 16/34 (47%), Positives = 21/34 (61%)
Query: 604 DLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
D+C G+C NT GSF C C +G+ S D + C D
Sbjct: 1 DVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCED 34
Score = 33.9 bits (74), Expect = 2.5
Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 14/84 (16%)
Query: 782 DECAVRPPPCDQLCHNTDGSYDCLCRTG--YELDEDGANC-----RDVDECER-DTHTCQ 833
D C + P P + + LC G Y D + N RD+DEC + C+
Sbjct: 160 DHCEIYPCPV-----YSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICK 214
Query: 834 Q-ICSNTEGSYECSCEDGYEKRGD 856
+ C NT+ YEC C+ G+ G+
Sbjct: 215 EGKCVNTQPGYECYCKQGFYYDGN 238
>M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein.
Length = 2444
Score = 240 bits (587), Expect = 2e-62
Identities = 184/572 (32%), Positives = 261/572 (45%), Gaps = 89/572 (15%)
Query: 67 PIDECDIMPQLCKPGTCHD-TPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ 125
P+D + GTC T T ++C C G+ + C+ D C+ PC Q
Sbjct: 101 PLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKS----CQQADPCASN--PCANGGQ 154
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQ-RICDHGD-CRNTIGSYRCECKPGYT 183
C+ ++ C CPP + P+ + DV+ECG + R+C HG C N +GSYRC C+ +T
Sbjct: 155 CLPFEASYICHCPPSFH-GPTCRQ--DVNECGQKPRLCRHGGTCHNEVGSYRCVCRATHT 211
Query: 184 LRENVCRDVDECSRPRPVCRNGTCENLPG-AYLCHCDDGFKAGPNNDCVDVNECREGGMV 242
N R CS P P GTC + C C GF G N + ++++C G
Sbjct: 212 -GPNCERPYVPCS-PSPCQNGGTCRPTGDVTHECACLPGF-TGQNCE-ENIDDC--PGNN 265
Query: 243 CRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGY 300
C+N G C + V ++ C C P +T G+ C DVDEC +P+ C G +C NT+GGY
Sbjct: 266 CKNGGACVDGVNTYNCPCPPEWT----GQYCTEDVDECQLMPNACQNGG--TCHNTHGGY 319
Query: 301 ECSCGAGWKLVGRRCVDR-DECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD 359
C C GW G C + D+C G C + + CECP G +T +C
Sbjct: 320 NCVCVNGW--TGEDCSENIDDCASAA-CFHGATCHDRVASFYCECPHG----RTGLLC-- 370
Query: 360 ERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMG 419
+ C ++ P C+EG+ C+ P A + C G
Sbjct: 371 HLNDAC----------------ISNP---CNEGS----NCDTNPVNGKA--ICTCPSGYT 405
Query: 420 RPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPR 477
P +QD+DEC + + C G+C+NT GSF C+C GY G C +D +EC +P
Sbjct: 406 GPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYT----GPRCEIDVNECVSNP- 460
Query: 478 ICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCP 536
C N TC + G ++C C PG+ +G V+ DECA RC + F+C CP
Sbjct: 461 -CQNDATCLDQIGEFQCMCMPGY-EGV-HCEVNTDECASSPCLHNGRCLDKINEFQCECP 517
Query: 537 YGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACE- 594
G+ G C+ D+DEC P C + +Y C C EGY T CE
Sbjct: 518 TGFT----GHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTH--------CEV 565
Query: 595 DINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
DI+EC+ D C G C + +F C C G+
Sbjct: 566 DIDECD--PDPCHYGSCKDGVATFTCLCRPGY 595
Score = 228 bits (558), Expect = 6e-59
Identities = 204/667 (30%), Positives = 282/667 (42%), Gaps = 113/667 (16%)
Query: 32 GAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCK-PGTCHDTPTGF 90
G+ C+ P G A+C P Y P ++ +DEC + C+ G C +T F
Sbjct: 384 GSNCDTNPVNGK----AIC-TCPSGYTGPACSQD--VDECSLGANPCEHAGKCINTLGSF 436
Query: 91 QCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDE 149
+C C GY T C DV+EC PC+ A C++ G F+C C PGY
Sbjct: 437 ECQCLQGY----TGPRCEIDVNECVSN--PCQNDATCLDQIGEFQCMCMPGYEGV----H 486
Query: 150 CE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGT- 206
CE + DEC +G C + I ++CEC G+T ++C+ DVDEC+ C+NG
Sbjct: 487 CEVNTDECASSPCLHNGRCLDKINEFQCECPTGFT--GHLCQYDVDECASTP--CKNGAK 542
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLT 266
C + P Y C C +G+ G + + VD++EC C G C++ V +F C C PGYT
Sbjct: 543 CLDGPNTYTCVCTEGY-TGTHCE-VDIDECDPDP--CHYGSCKDGVATFTCLCRPGYT-- 596
Query: 267 ADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKEL 324
G +C +++EC PC G +C + + Y C C G G C ++ D+C
Sbjct: 597 --GHHCETNINECSS--QPCRLRG--TCQDPDNAYLCFCLKG--TTGPNCEINLDDCASS 648
Query: 325 PYVCAGGECRNFNGGYVCECPAGWRFDKTAAVC---VDE-------RKELCYDEWEAGRC 374
P C G C + GY C C G+ T ++C +DE C D C
Sbjct: 649 P--CDSGTCLDKIDGYECACEPGY----TGSMCNSNIDECAGNPCHNGGTCEDGINGFTC 702
Query: 375 HRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRI-CQGGMGRPNLTQDLDECRVR 433
P P C C DS + C G N + +EC
Sbjct: 703 RC--PEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESN 760
Query: 434 PDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGY 491
P CV GG C + C C +G+ G +C + +ECA +P + GTC + GY
Sbjct: 761 P--CVNGGTCKDMTSGIVCTCREGF----SGPNCQTNINECASNPCL-NKGTCIDDVAGY 813
Query: 492 ECQCSPGFTQGPDQTC-VDVDECAEGRASCTFRCHNTAG--SFRCTCPYGYAVAADGVHC 548
+C C +T TC V + CA C + SF C CP A G C
Sbjct: 814 KCNCLLPYTGA---TCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCP---TAGAKGQTC 867
Query: 549 R-DIDECVQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQED 604
DI+ECV P C H +C+N G Y C C GY S CE DI++C
Sbjct: 868 EVDINECVLSP--CRHGASCQNTHGXYRCHCQAGY--------SGRNCETDIDDCRPNP- 916
Query: 605 LC-SGGVCINTDGSFLCDCDAGF--------------EPSEDG---TDCIDRRTGTCYRS 646
C +GG C + + CDC GF +P +G TDC+D T TC
Sbjct: 917 -CHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAG 975
Query: 647 LVSGRCE 653
CE
Sbjct: 976 FSGIHCE 982
Score = 223 bits (544), Expect = 3e-57
Identities = 180/586 (30%), Positives = 261/586 (44%), Gaps = 89/586 (15%)
Query: 65 TKPIDECDIMPQLCK-PGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGM 123
T+ +DEC +MP C+ GTCH+T G+ C C +G+ ++ S ++D+C+ C
Sbjct: 293 TEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCS---ENIDDCA--SAACFHG 347
Query: 124 AQCVNLPGAFECRCPPGYR-LTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY 182
A C + +F C CP G L L++ + C + CD G C C GY
Sbjct: 348 ATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVN---GKAICTCPSGY 404
Query: 183 TLRENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGM 241
T +DVDECS C + G C N G++ C C G+ GP + +DVNEC
Sbjct: 405 T-GPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY-TGPRCE-IDVNECVSN-- 459
Query: 242 VCRN-GRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGG 299
C+N C + +G F+C C PGY +G +C + DEC PC +G C +
Sbjct: 460 PCQNDATCLDQIGEFQCMCMPGY----EGVHCEVNTDEC--ASSPCLHNGR--CLDKINE 511
Query: 300 YECSCGAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVC 357
++C C G+ G C D DEC P C G +C + Y C C G+ T C
Sbjct: 512 FQCECPTGF--TGHLCQYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGY----TGTHC 563
Query: 358 VDERKELCYDEWEAGRCHRARPLQ-LARPECCCSEGAAWGRYCE---------------R 401
E+ DE + CH +A C C G G +CE
Sbjct: 564 -----EVDIDECDPDPCHYGSCKDGVATFTCLCRPGYT-GHHCETNINECSSQPCRLRGT 617
Query: 402 CPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAP 461
C PD+A ++ C G PN +LD+C P C G C++ + C C GY
Sbjct: 618 CQDPDNA-YLCFCLKGTTGPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPGYT--- 671
Query: 462 DGLSC-VDADECALDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRA 518
G C + DECA +P C N GTC + G+ C+C G+ D TC+ +V+EC
Sbjct: 672 -GSMCNSNIDECAGNP--CHNGGTCEDGINGFTCRCPEGY---HDPTCLSEVNEC-NSNP 724
Query: 519 SCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI--DECVQEPRVCPHACENVVGSYICKC 576
C ++ ++C C G++ G +C DI +EC P V C+++ +C C
Sbjct: 725 CVHGACRDSLNGYKCDCDPGWS----GTNC-DINNNECESNPCVNGGTCKDMTSGIVCTC 779
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDC 622
EG+ S P N +INEC L + G CI+ + C+C
Sbjct: 780 REGF---SGP----NCQTNINECASNPCL-NKGTCIDDVAGYKCNC 817
Score = 219 bits (536), Expect = 3e-56
Identities = 241/855 (28%), Positives = 337/855 (39%), Gaps = 139/855 (16%)
Query: 33 APCE---ACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPG-TCHDTPT 88
+PC+ C P G H C PG + E ID+C CK G C D
Sbjct: 225 SPCQNGGTCRPTGDVTHECAC--LPG-FTGQNCEEN--IDDCP--GNNCKNGGACVDGVN 277
Query: 89 GFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
+ C C + T C DVDEC C+ C N G + C C G+
Sbjct: 278 TYNCPCPPEW----TGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWT---GE 330
Query: 148 DECEDVDECGDQRICDHG-DCRNTIGSYRCECKPGYTLRENVCRDVDEC-SRPRPVCRNG 205
D E++D+C C HG C + + S+ CEC G T +C D C S P C G
Sbjct: 331 DCSENIDDCASAA-CFHGATCHDRVASFYCECPHGRT--GLLCHLNDACISNP---CNEG 384
Query: 206 T-CENLP--GAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTVGSFRCECAP 261
+ C+ P G +C C G+ GP DV+EC G C + G+C NT+GSF C+C
Sbjct: 385 SNCDTNPVNGKAICTCPSGY-TGPACS-QDVDECSLGANPCEHAGKCINTLGSFECQCLQ 442
Query: 262 GYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRD 319
GYT G C DV+EC + +PC D +C + G ++C C G++ G C V+ D
Sbjct: 443 GYT----GPRCEIDVNEC--VSNPCQNDA--TCLDQIGEFQCMCMPGYE--GVHCEVNTD 492
Query: 320 ECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARP 379
EC P + G C + + CECP G+ T +C +++ C
Sbjct: 493 ECASSPCL-HNGRCLDKINEFQCECPTGF----TGHLC----------QYDVDEC----- 532
Query: 380 LQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG 439
+ P C GA C P++ + +C G + D+DEC PD C
Sbjct: 533 --ASTP---CKNGAK----C--LDGPNT--YTCVCTEGYTGTHCEVDIDECD--PDPCHY 577
Query: 440 GRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICG-NGTCSNTRGGYECQCSP 497
G C + +F C C GY G C + +EC+ P C GTC + Y C C
Sbjct: 578 GSCKDGVATFTCLCRPGYT----GHHCETNINECSSQP--CRLRGTCQDPDNAYLCFCLK 631
Query: 498 GFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQ 556
G T GP+ +++D+CA + C + + C C GY G C +IDEC
Sbjct: 632 G-TTGPNCE-INLDDCASSPCD-SGTCLDKIDGYECACEPGYT----GSMCNSNIDECAG 684
Query: 557 EPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQ--EDLCSGGVCINT 614
P CE+ + + C+CPEGY + + N C N C D +G C
Sbjct: 685 NPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEV-NECNS-NPCVHGACRDSLNGYKCDCD 742
Query: 615 DGSFLCDCDAG-----FEPSEDGTDCIDRRTG---TCYRSLVSGRCEPEXXXXXXXXXXX 666
G +CD P +G C D +G TC C+
Sbjct: 743 PGWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNINECASNPCLN 802
Query: 667 XXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXX 726
V +C C L G+ CE+ AP +P+ C
Sbjct: 803 KGTCIDD------VAGYKCNCLLPYT-GATCEVVLAPCAPSP---CRNGGEC-RQSEDYE 851
Query: 727 XXXXXXXXXXXXXXXLDVFADVDECAAIP----GLC--APGRFRCVCGPGYRPAGEVC-A 779
+V D++EC P C G +RC C GY +G C
Sbjct: 852 SFSCVCPTAGAKGQTCEV--DINECVLSPCRHGASCQNTHGXYRCHCQAGY--SGRNCET 907
Query: 780 DVDECAVRPPPCDQLCHNTDG--SYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQIC 836
D+D+C RP PC TDG + C C G+ G C D++EC D C
Sbjct: 908 DIDDC--RPNPCHNGGSCTDGINTAFCDCLPGFR----GTFCEEDINECASDPCRNGANC 961
Query: 837 SNTEGSYECSCEDGY 851
++ SY C+C G+
Sbjct: 962 TDCVDSYTCTCPAGF 976
Score = 209 bits (511), Expect = 3e-53
Identities = 201/677 (29%), Positives = 282/677 (41%), Gaps = 107/677 (15%)
Query: 20 KYLCCCSVGHAWGAPC----EACPPRGSPA-HTALCGEKPGEY-INPVTNETKPIDECDI 73
K +C C G+ G C + C +P H C G + + T P E D+
Sbjct: 395 KAICTCPSGYT-GPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDV 453
Query: 74 MPQLCKP----GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
+ P TC D FQC C GYE H + DEC+ PC +C++
Sbjct: 454 NECVSNPCQNDATCLDQIGEFQCMCMPGYEG---VHCEVNTDECA--SSPCLHNGRCLDK 508
Query: 130 PGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENV 188
F+C CP G+ T L C+ DVDEC + C + +Y C C GYT
Sbjct: 509 INEFQCECPTGF--TGHL--CQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTH-- 562
Query: 189 CR-DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVCR-N 245
C D+DEC P P C G+C++ + C C G+ + C ++NEC CR
Sbjct: 563 CEVDIDECD-PDP-CHYGSCKDGVATFTCLCRPGYTG---HHCETNINEC--SSQPCRLR 615
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
G C++ ++ C C G T G NC ++D+C P G +C + GYEC+C
Sbjct: 616 GTCQDPDNAYLCFCLKGTT----GPNCEINLDDCASSPCDSG-----TCLDKIDGYECAC 666
Query: 305 GAGWKLVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
G+ G C DEC P C GG C + G+ C CP G+ D T C+ E
Sbjct: 667 EPGY--TGSMCNSNIDECAGNP--CHNGGTCEDGINGFTCRCPEGYH-DPT---CLSEVN 718
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCSEGAAW------GRYCERCPAPD-------SAE 409
E + G C + L +C C G + CE P + ++
Sbjct: 719 ECNSNPCVHGACRDS----LNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSG 774
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSC-V 467
+ C+ G PN +++EC P C+ G C++ ++C C +L G +C V
Sbjct: 775 IVCTCREGFSGPNCQTNINECASNP--CLNKGTCIDDVAGYKCNC----LLPYTGATCEV 828
Query: 468 DADECALDPRICGNG-TCSNTRG--GYECQCSPGFTQGPDQTC-VDVDECAEGRASCTFR 523
CA P C NG C + + C C +G QTC VD++EC
Sbjct: 829 VLAPCAPSP--CRNGGECRQSEDYESFSCVCPTAGAKG--QTCEVDINECVLSPCRHGAS 884
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRR 582
C NT G +RC C GY+ G +C DID+C P +C + + + C C G+R
Sbjct: 885 CQNTHGXYRCHCQAGYS----GRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRG 940
Query: 583 TSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLCDCDAGFE--PSEDGT-DCIDR 638
T EDINEC D C G C + S+ C C AGF E+ T DC +
Sbjct: 941 TFCE-------EDINECAS--DPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTES 991
Query: 639 ---RTGTCYRSLVSGRC 652
GTC + S C
Sbjct: 992 SCFNGGTCVDGINSFTC 1008
Score = 206 bits (502), Expect = 3e-52
Identities = 193/677 (28%), Positives = 275/677 (40%), Gaps = 94/677 (13%)
Query: 19 TKYLCCCSVGHAWGAPCE---ACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMP 75
T +C ++ G PC C G T C P Y +P ++EC+ P
Sbjct: 671 TGSMCNSNIDECAGNPCHNGGTCED-GINGFTCRC---PEGYHDPTC--LSEVNECNSNP 724
Query: 76 QLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC 135
C G C D+ G++C CD G+ N C D++ PC C ++ C
Sbjct: 725 --CVHGACRDSLNGYKCDCDPGWSGTN----C-DINNNECESNPCVNGGTCKDMTSGIVC 777
Query: 136 RCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDE 194
C G+ S C+ +++EC + G C + + Y+C C YT C V
Sbjct: 778 TCREGF----SGPNCQTNINECASNPCLNKGTCIDDVAGYKCNCLLPYT--GATCEVVLA 831
Query: 195 CSRPRPVCRNG-TCENLPG--AYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CRN 250
P P CRNG C ++ C C G + VD+NEC CR+G C+N
Sbjct: 832 PCAPSP-CRNGGECRQSEDYESFSCVCPTAGAKGQTCE-VDINECVLSP--CRHGASCQN 887
Query: 251 TVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
T G +RC C GY+ GRNC D+D+C P+PC G SCT+ C C G++
Sbjct: 888 THGXYRCHCQAGYS----GRNCETDIDDCR--PNPCHNGG--SCTDGINTAFCDCLPGFR 939
Query: 310 LVGRRCV-DRDECKELPYVCAGG-ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYD 367
G C D +EC P C G C + Y C CPAG+ D + C++
Sbjct: 940 --GTFCEEDINECASDP--CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFN 995
Query: 368 EWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP-DSAEFMR--ICQGGMGR---- 420
G C + C C G G YC+ DS + CQ G G
Sbjct: 996 ---GGTCVDG----INSFTCLCPPGFT-GSYCQHVVNECDSRPCLLGGTCQDGRGLHRCT 1047
Query: 421 -------PNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYV-LAPD--GLSC-VD 468
PN + C P C GG+C T +RCECP G+ L D +SC V
Sbjct: 1048 CPQGYTGPNCQNLVHWCDSSP--CKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVA 1105
Query: 469 ADECALD-PRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCH 525
A +D R+C +G C + + C+C G+T C D VDEC+ C
Sbjct: 1106 AQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT---GSYCEDLVDECSPSPCQNGATCT 1162
Query: 526 NTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
+ G + C C GY GV+C +IDEC+ P C ++ +Y C CP G +
Sbjct: 1163 DYLGGYSCKCVAGY----HGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVH 1218
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF--EPSE-DGTDCID---- 637
+ ++ ++ + G C++ G + C C GF E E D +C+
Sbjct: 1219 CEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCD 1278
Query: 638 -RRTGTCYRSLVSGRCE 653
R T C + + CE
Sbjct: 1279 ARGTQNCVQRVNDFHCE 1295
Score = 186 bits (453), Expect = 3e-46
Identities = 191/623 (30%), Positives = 258/623 (41%), Gaps = 108/623 (17%)
Query: 60 PVTNETKPIDECDIMPQLCKPG-TCHDTPT--GFQCGCDHGYEHDNTSHLCRDVDECSWG 116
P T T + P C+ G C + F C C T + D++EC
Sbjct: 820 PYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTAGAKGQTCEV--DINECVLS 877
Query: 117 RPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYR 175
PCR A C N G + C C GY S CE D+D+C + G C + I +
Sbjct: 878 --PCRHGASCQNTHGXYRCHCQAGY----SGRNCETDIDDCRPNPCHNGGSCTDGINTAF 931
Query: 176 CECKPGYTLRENVCR-DVDECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVDV 233
C+C PG+ R C D++EC+ CRNG C + +Y C C GF + +
Sbjct: 932 CDCLPGF--RGTFCEEDINECASDP--CRNGANCTDCVDSYTCTCPAGFSGIHCEN--NT 985
Query: 234 NECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRDV-DECDELPHPCGRDGNP 291
+C E C NG C + + SF C C PG+T G C+ V +ECD PC G
Sbjct: 986 PDCTESS--CFNGGTCVDGINSFTCLCPPGFT----GSYCQHVVNECDS--RPCLLGG-- 1035
Query: 292 SCTNTNGGYECSCGAGWKLVGRRCVDRDE-CKELPYVCA-GGECRNFNGGYVCECPAGWR 349
+C + G + C+C G+ G C + C P C GG+C + Y CECP+GW
Sbjct: 1036 TCQDGRGLHRCTCPQGY--TGPNCQNLVHWCDSSP--CKNGGKCWQTHTQYRCECPSGW- 1090
Query: 350 FDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAE 409
T C D C E A R + + +AR C G C +
Sbjct: 1091 ---TGLYC-DVPSVSC--EVAAQR----QGVDVAR---LCQHGGL-------CVDAGNTH 1130
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVD 468
R CQ G +DEC P C G C + G + C+C GY G++C +
Sbjct: 1131 HCR-CQAGYTGSYCEDLVDECS--PSPCQNGATCTDYLGGYSCKCVAGY----HGVNCSE 1183
Query: 469 A-DECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAE-----GRASCT 521
DEC P C NG TC + Y+C C G TQG ++VD+C R+
Sbjct: 1184 EIDECLSHP--CQNGGTCLDLPNTYKCSCPRG-TQGVHCE-INVDDCNPPVDPVSRSPKC 1239
Query: 522 FR---CHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVC--PHACENVVGSYICK 575
F C + G + CTCP G+ G C D++EC+ P C V + C+
Sbjct: 1240 FNNGTCVDQVGGYSCTCPPGFV----GERCEGDVNECLSNPCDARGTQNCVQRVNDFHCE 1295
Query: 576 CPEGYRRTSAPQDSENACED-INECEEQEDLC-SGGVCI---NTDGSFLCDCDAGFEPSE 630
C G+ + CE IN C+ + C +GG C NT F+C C AGFE
Sbjct: 1296 CRAGH--------TGRRCESVINGCKGKP--CKNGGTCAVASNTARGFICKCPAGFE--- 1342
Query: 631 DGTDC-IDRRTGTCYRSLVSGRC 652
G C D RT R L G C
Sbjct: 1343 -GATCENDARTCGSLRCLNGGTC 1364
Score = 186 bits (452), Expect = 4e-46
Identities = 155/463 (33%), Positives = 190/463 (41%), Gaps = 73/463 (15%)
Query: 195 CSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRC---- 248
CS+P C NG CE G C C F GP C D N C C+N G C
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAF-VGPR--CQDPNPCLS--TPCKNAGTCHVVD 78
Query: 249 RNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
R V + C CA G++ G C + L +PC R+G T Y+C C GW
Sbjct: 79 RRGVADYACSCALGFS----GPLCLTPLDNACLTNPC-RNGGTCDLLTLTEYKCRCPPGW 133
Query: 309 KLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDE---RKEL 364
G+ C D C P CA GG+C F Y+C CP + T V+E + L
Sbjct: 134 S--GKSCQQADPCASNP--CANGGQCLPFEASYICHCPPSFH-GPTCRQDVNECGQKPRL 188
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQ-GGMGRP-- 421
C G CH ++ C C G CER P S CQ GG RP
Sbjct: 189 CR---HGGTCHN----EVGSYRCVC-RATHTGPNCERPYVPCSPS---PCQNGGTCRPTG 237
Query: 422 NLTQDL--------DECRVRPDVCVGGRCVN----TDG--SFRCECPDGYVLAPDGLSCV 467
++T + C D C G C N DG ++ C CP + G C
Sbjct: 238 DVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCPPEWT----GQYCT 293
Query: 468 -DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
D DEC L P C NG TC NT GGY C C G+T G D ++D+CA CH
Sbjct: 294 EDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWT-GED-CSENIDDCASAACFHGATCH 351
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN--VVGSYICKCPEGYRRT 583
+ SF C CP+G G+ C D C+ P C+ V G IC CP GY
Sbjct: 352 DRVASFYCECPHG----RTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGP 407
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
+ QD + N CE G CINT GSF C C G+
Sbjct: 408 ACSQDVDECSLGANPCEH------AGKCINTLGSFECQCLQGY 444
Score = 149 bits (360), Expect = 5e-35
Identities = 174/639 (27%), Positives = 245/639 (38%), Gaps = 99/639 (15%)
Query: 21 YLCCCSVGHAWGAPCEACPPRG--SPA-HTALCGEKPGEYINPVT------NETKPIDEC 71
+ C C A G CE SP H A C G Y N ID+C
Sbjct: 853 FSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAGYSGRNCETDIDDC 912
Query: 72 DIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNL 129
P C G+C D C C G+ C D++EC+ PCR A C +
Sbjct: 913 --RPNPCHNGGSCTDGINTAFCDCLPGFR----GTFCEEDINECA--SDPCRNGANCTDC 964
Query: 130 PGAFECRCPPGYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENV 188
++ C CP G+ S CE+ +C + + G C + I S+ C C PG+T +
Sbjct: 965 VDSYTCTCPAGF----SGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT--GSY 1018
Query: 189 CRDV-DECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG- 246
C+ V +EC RP GTC++ G + C C G+ GPN + V+ C C+NG
Sbjct: 1019 CQHVVNECDS-RPCLLGGTCQDGRGLHRCTCPQGY-TGPNCQNL-VHWCDSSP--CKNGG 1073
Query: 247 RCRNTVGSFRCECAPGYT-LTAD--GRNCRDVDECD--ELPHPCGRDGNPSCTNTNGGYE 301
+C T +RCEC G+T L D +C + ++ C G C + +
Sbjct: 1074 KCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGG--LCVDAGNTHH 1131
Query: 302 CSCGAGWKLVGRRCVDR-DECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVD 359
C C AG+ G C D DEC P C G C ++ GGY C+C AG+ C +
Sbjct: 1132 CRCQAGY--TGSYCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVAGYH----GVNCSE 1183
Query: 360 ERKE-LCYDEWEAGRCHRARPLQLARP-ECCCSEGAAWGRYCERCPAPDSAEFMRICQGG 417
E E L + G C L L +C C G G +CE
Sbjct: 1184 EIDECLSHPCQNGGTC-----LDLPNTYKCSCPRGTQ-GVHCE----------------- 1220
Query: 418 MGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDP 476
+ + +D P G CV+ G + C CP G+V G C D +EC +P
Sbjct: 1221 INVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV----GERCEGDVNECLSNP 1276
Query: 477 -RICGNGTCSNTRGGYECQCSPGFTQGPDQTCVD---VDECAEGRASCTFRCHNTAGSFR 532
G C + C+C G T ++ ++ C G +C NTA F
Sbjct: 1277 CDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNG-GTCAV-ASNTARGFI 1334
Query: 533 CTCPYGY--------AVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
C CP G+ A + C + C+ PR C C+ P
Sbjct: 1335 CKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLG 1394
Query: 585 A-PQDSENACEDINECEEQEDLC----SGGVCINTDGSF 618
P ++ CE +E LC +G +C D SF
Sbjct: 1395 GNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSF 1433
Score = 100 bits (239), Expect = 3e-20
Identities = 105/362 (29%), Positives = 144/362 (39%), Gaps = 54/362 (14%)
Query: 321 CKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARP 379
C + C GG+C NG C C G F C D L AG CH
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVC--GGAF--VGPRCQDPNPCLSTPCKNAGTCHVVDR 79
Query: 380 LQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP----- 434
+A C C+ G + G C D+A C+ G LT +CR P
Sbjct: 80 RGVADYACSCALGFS-GPLC--LTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGK 136
Query: 435 -----DVCV------GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNG 482
D C GG+C+ + S+ C CP + G +C D +EC PR+C +G
Sbjct: 137 SCQQADPCASNPCANGGQCLPFEASYICHCPPSF----HGPTCRQDVNECGQKPRLCRHG 192
Query: 483 -TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAG-SFRCTCPYGYA 540
TC N G Y C C T GP+ V C+ C T + C C G+
Sbjct: 193 GTCHNEVGSYRCVCRATHT-GPNCERPYVP-CSPSPCQNGGTCRPTGDVTHECACLPGFT 250
Query: 541 VAADGVHCRD-IDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENAC-EDINE 598
G +C + ID+C AC + V +Y C CP P+ + C ED++E
Sbjct: 251 ----GQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCP--------PEWTGQYCTEDVDE 298
Query: 599 CEEQEDLC-SGGVCINTDGSFLCDCDAGF---EPSEDGTDCIDR---RTGTCYRSLVSGR 651
C+ + C +GG C NT G + C C G+ + SE+ DC TC+ + S
Sbjct: 299 CQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFY 358
Query: 652 CE 653
CE
Sbjct: 359 CE 360
Score = 66.5 bits (155), Expect = 4e-10
Identities = 72/263 (27%), Positives = 96/263 (36%), Gaps = 35/263 (13%)
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
P+D P+ GTC D G+ C C G+ + DV+EC RG C
Sbjct: 1229 PVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE---GDVNECLSNPCDARGTQNC 1285
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDV-DECGDQRICDHGDC---RNTIGSYRCECKPGY 182
V F C C G+ + CE V + C + + G C NT + C+C G+
Sbjct: 1286 VQRVNDFHCECRAGH----TGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGF 1341
Query: 183 TLRENVC-RDVDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGG 240
C D C R C N GTC + P + C C F GP + C G
Sbjct: 1342 --EGATCENDARTCGSLR--CLNGGTCISGPRSPTCLCLGPF-TGPECQFPASSPCLGGN 1396
Query: 241 MVCRNGRCRNTVGS--FRCECAPGYT--------LTADGRNCRD-----VDECDELPHPC 285
G C T S +RC C + + G RD ++E ELP C
Sbjct: 1397 PCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPE-C 1455
Query: 286 GRD-GNPSCTNTNGGYECSCGAG 307
D GN C+ + C G
Sbjct: 1456 QEDAGNKVCSLQCNNHACGWDGG 1478
Score = 65.3 bits (152), Expect = 9e-10
Identities = 36/96 (37%), Positives = 48/96 (50%), Gaps = 10/96 (10%)
Query: 761 GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDEDGA 817
G+ C C GY G C+ DVDEC++ PC+ C NT GS++C C GY G
Sbjct: 394 GKAICTCPSGY--TGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYT----GP 447
Query: 818 NCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
C DV+EC + C + G ++C C GYE
Sbjct: 448 RCEIDVNECVSNPCQNDATCLDQIGEFQCMCMPGYE 483
Score = 60.1 bits (139), Expect = 3e-08
Identities = 43/112 (38%), Positives = 50/112 (44%), Gaps = 18/112 (16%)
Query: 747 DVDECAAIPGLC--APGRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTD--GS 801
DV GLC A C C GY G C D VDEC+ P PC TD G
Sbjct: 1112 DVARLCQHGGLCVDAGNTHHCRCQAGY--TGSYCEDLVDECS--PSPCQNGATCTDYLGG 1167
Query: 802 YDCLCRTGYELDEDGANC-RDVDECERDTHTCQQ--ICSNTEGSYECSCEDG 850
Y C C GY G NC ++DEC +H CQ C + +Y+CSC G
Sbjct: 1168 YSCKCVAGYH----GVNCSEEIDECL--SHPCQNGGTCLDLPNTYKCSCPRG 1213
Score = 56.4 bits (130), Expect = 4e-07
Identities = 33/98 (33%), Positives = 45/98 (45%), Gaps = 9/98 (9%)
Query: 763 FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F CVC P G+ C D++EC + P C NT G Y C C+ GY G NC
Sbjct: 853 FSCVC-PTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAGY----SGRNCET 907
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
D+D+C + C++ + C C G+ RG C
Sbjct: 908 DIDDCRPNPCHNGGSCTDGINTAFCDCLPGF--RGTFC 943
Score = 54.0 bits (124), Expect = 2e-06
Identities = 30/88 (34%), Positives = 40/88 (45%), Gaps = 9/88 (10%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 821
++C C PG+ +G+ C D CA P C + SY C C + G CR D
Sbjct: 125 YKCRCPPGW--SGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFH----GPTCRQD 178
Query: 822 VDECERDTHTCQQ--ICSNTEGSYECSC 847
V+EC + C+ C N GSY C C
Sbjct: 179 VNECGQKPRLCRHGGTCHNEVGSYRCVC 206
Score = 50.8 bits (116), Expect = 2e-05
Identities = 38/114 (33%), Positives = 50/114 (43%), Gaps = 17/114 (14%)
Query: 749 DECAAIP----GLCAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTD 799
D CA+ P G C P + C C P + G C DV+EC +P C CHN
Sbjct: 142 DPCASNPCANGGQCLPFEASYICHCPPSFH--GPTCRQDVNECGQKPRLCRHGGTCHNEV 199
Query: 800 GSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNT-EGSYECSCEDGY 851
GSY C+CR + G NC R C C T + ++EC+C G+
Sbjct: 200 GSYRCVCRATH----TGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGF 249
Score = 50.0 bits (114), Expect = 4e-05
Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 15/110 (13%)
Query: 756 GLCAPG---RFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYE 811
G C P C C PG+ G+ C + +D+C C + +Y+C C +
Sbjct: 231 GTCRPTGDVTHECACLPGF--TGQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCPPEWT 288
Query: 812 LDEDGANC-RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
G C DVDEC+ + CQ C NT G Y C C +G+ G+ C
Sbjct: 289 ----GQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW--TGEDC 332
Score = 49.6 bits (113), Expect = 5e-05
Identities = 32/100 (32%), Positives = 41/100 (41%), Gaps = 10/100 (10%)
Query: 756 GLCAPG--RFRCVCGPGYRPAGEVCADV-DECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G C G F C+C PG+ G C V +EC RP C + G + C C GY
Sbjct: 997 GTCVDGINSFTCLCPPGF--TGSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGY-- 1052
Query: 813 DEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
G NC++ V C+ C T Y C C G+
Sbjct: 1053 --TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGW 1090
Score = 46.4 bits (105), Expect = 4e-04
Identities = 34/102 (33%), Positives = 46/102 (45%), Gaps = 19/102 (18%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCD----QLCHNTDGSYDCLCRTGYELDED 815
G + C C PG+ GE C DV+EC P CD Q C + C CR G+
Sbjct: 1250 GGYSCTCPPGF--VGERCEGDVNECLSNP--CDARGTQNCVQRVNDFHCECRAGHT---- 1301
Query: 816 GANCRDV-DECE----RDTHTCQQICSNTEGSYECSCEDGYE 852
G C V + C+ ++ TC + SNT + C C G+E
Sbjct: 1302 GRRCESVINGCKGKPCKNGGTCA-VASNTARGFICKCPAGFE 1342
Score = 45.6 bits (103), Expect = 8e-04
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 19/123 (15%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHN 797
DVDEC +P C G + CVC G+ GE C++ +D+CA CH+
Sbjct: 295 DVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW--TGEDCSENIDDCASAACFHGATCHD 352
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSN--TEGSYECSCEDGYEKRG 855
S+ C C G G C D C + C G C+C GY G
Sbjct: 353 RVASFYCECPHG----RTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGY--TG 406
Query: 856 DAC 858
AC
Sbjct: 407 PAC 409
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/129 (27%), Positives = 52/129 (40%), Gaps = 24/129 (18%)
Query: 748 VDECAAIP----GLCAP--GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDG 800
VDEC+ P C G + C C GY G C++ +DEC P C +
Sbjct: 1147 VDECSPSPCQNGATCTDYLGGYSCKCVAGYH--GVNCSEEIDECLSHPCQNGGTCLDLPN 1204
Query: 801 SYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQ--------ICSNTEGSYECSCEDGY 851
+Y C C G + G +C +VD+C + C + G Y C+C G+
Sbjct: 1205 TYKCSCPRGTQ----GVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGF 1260
Query: 852 EKRGDACVG 860
G+ C G
Sbjct: 1261 V--GERCEG 1267
Score = 40.3 bits (90), Expect = 0.028
Identities = 32/113 (28%), Positives = 46/113 (40%), Gaps = 19/113 (16%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCH 796
DV+EC P LC G +RCVC + G C + P PC C
Sbjct: 178 DVNECGQKPRLCRHGGTCHNEVGSYRCVCRATH--TGPNC-ERPYVPCSPSPCQNGGTCR 234
Query: 797 NT-DGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSC 847
T D +++C C G+ G NC + +D+C + C + +Y C C
Sbjct: 235 PTGDVTHECACLPGF----TGQNCEENIDDCPGNNCKNGGACVDGVNTYNCPC 283
Score = 39.9 bits (89), Expect = 0.038
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 5/59 (8%)
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
LC + ++ C C+ GY G+ C D VDEC C++ G Y C C GY
Sbjct: 1122 LCVDAGNTHHCRCQAGYT----GSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY 1176
Score = 31.9 bits (69), Expect = 10.0
Identities = 26/99 (26%), Positives = 36/99 (36%), Gaps = 11/99 (11%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHN-TDGSYDCLCRTGYELDEDGANC 819
+ C C G+ +G +C + A PC C T Y C C G+ G +C
Sbjct: 85 YACSCALGF--SGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWS----GKSC 138
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
+ D C + C E SY C C + G C
Sbjct: 139 QQADPCASNPCANGGQCLPFEASYICHCPPSF--HGPTC 175
>AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein.
Length = 2556
Score = 240 bits (587), Expect = 2e-62
Identities = 184/572 (32%), Positives = 261/572 (45%), Gaps = 89/572 (15%)
Query: 67 PIDECDIMPQLCKPGTCHD-TPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ 125
P+D + GTC T T ++C C G+ + C+ D C+ PC Q
Sbjct: 101 PLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKS----CQQADPCASN--PCANGGQ 154
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQ-RICDHGD-CRNTIGSYRCECKPGYT 183
C+ ++ C CPP + P+ + DV+ECG + R+C HG C N +GSYRC C+ +T
Sbjct: 155 CLPFEASYICHCPPSFH-GPTCRQ--DVNECGQKPRLCRHGGTCHNEVGSYRCVCRATHT 211
Query: 184 LRENVCRDVDECSRPRPVCRNGTCENLPG-AYLCHCDDGFKAGPNNDCVDVNECREGGMV 242
N R CS P P GTC + C C GF G N + ++++C G
Sbjct: 212 -GPNCERPYVPCS-PSPCQNGGTCRPTGDVTHECACLPGF-TGQNCE-ENIDDC--PGNN 265
Query: 243 CRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGY 300
C+N G C + V ++ C C P +T G+ C DVDEC +P+ C G +C NT+GGY
Sbjct: 266 CKNGGACVDGVNTYNCPCPPEWT----GQYCTEDVDECQLMPNACQNGG--TCHNTHGGY 319
Query: 301 ECSCGAGWKLVGRRCVDR-DECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD 359
C C GW G C + D+C G C + + CECP G +T +C
Sbjct: 320 NCVCVNGW--TGEDCSENIDDCASAA-CFHGATCHDRVASFYCECPHG----RTGLLC-- 370
Query: 360 ERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMG 419
+ C ++ P C+EG+ C+ P A + C G
Sbjct: 371 HLNDAC----------------ISNP---CNEGS----NCDTNPVNGKA--ICTCPSGYT 405
Query: 420 RPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPR 477
P +QD+DEC + + C G+C+NT GSF C+C GY G C +D +EC +P
Sbjct: 406 GPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYT----GPRCEIDVNECVSNP- 460
Query: 478 ICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCP 536
C N TC + G ++C C PG+ +G V+ DECA RC + F+C CP
Sbjct: 461 -CQNDATCLDQIGEFQCMCMPGY-EGV-HCEVNTDECASSPCLHNGRCLDKINEFQCECP 517
Query: 537 YGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACE- 594
G+ G C+ D+DEC P C + +Y C C EGY T CE
Sbjct: 518 TGFT----GHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTH--------CEV 565
Query: 595 DINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
DI+EC+ D C G C + +F C C G+
Sbjct: 566 DIDECD--PDPCHYGSCKDGVATFTCLCRPGY 595
Score = 228 bits (558), Expect = 6e-59
Identities = 204/667 (30%), Positives = 282/667 (42%), Gaps = 113/667 (16%)
Query: 32 GAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCK-PGTCHDTPTGF 90
G+ C+ P G A+C P Y P ++ +DEC + C+ G C +T F
Sbjct: 384 GSNCDTNPVNGK----AIC-TCPSGYTGPACSQD--VDECSLGANPCEHAGKCINTLGSF 436
Query: 91 QCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDE 149
+C C GY T C DV+EC PC+ A C++ G F+C C PGY
Sbjct: 437 ECQCLQGY----TGPRCEIDVNECVSN--PCQNDATCLDQIGEFQCMCMPGYEGV----H 486
Query: 150 CE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGT- 206
CE + DEC +G C + I ++CEC G+T ++C+ DVDEC+ C+NG
Sbjct: 487 CEVNTDECASSPCLHNGRCLDKINEFQCECPTGFT--GHLCQYDVDECASTP--CKNGAK 542
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLT 266
C + P Y C C +G+ G + + VD++EC C G C++ V +F C C PGYT
Sbjct: 543 CLDGPNTYTCVCTEGY-TGTHCE-VDIDECDPDP--CHYGSCKDGVATFTCLCRPGYT-- 596
Query: 267 ADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKEL 324
G +C +++EC PC G +C + + Y C C G G C ++ D+C
Sbjct: 597 --GHHCETNINECSS--QPCRLRG--TCQDPDNAYLCFCLKG--TTGPNCEINLDDCASS 648
Query: 325 PYVCAGGECRNFNGGYVCECPAGWRFDKTAAVC---VDE-------RKELCYDEWEAGRC 374
P C G C + GY C C G+ T ++C +DE C D C
Sbjct: 649 P--CDSGTCLDKIDGYECACEPGY----TGSMCNSNIDECAGNPCHNGGTCEDGINGFTC 702
Query: 375 HRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRI-CQGGMGRPNLTQDLDECRVR 433
P P C C DS + C G N + +EC
Sbjct: 703 RC--PEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESN 760
Query: 434 PDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGY 491
P CV GG C + C C +G+ G +C + +ECA +P + GTC + GY
Sbjct: 761 P--CVNGGTCKDMTSGIVCTCREGF----SGPNCQTNINECASNPCL-NKGTCIDDVAGY 813
Query: 492 ECQCSPGFTQGPDQTC-VDVDECAEGRASCTFRCHNTAG--SFRCTCPYGYAVAADGVHC 548
+C C +T TC V + CA C + SF C CP A G C
Sbjct: 814 KCNCLLPYTGA---TCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCP---TAGAKGQTC 867
Query: 549 R-DIDECVQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQED 604
DI+ECV P C H +C+N G Y C C GY S CE DI++C
Sbjct: 868 EVDINECVLSP--CRHGASCQNTHGXYRCHCQAGY--------SGRNCETDIDDCRPNP- 916
Query: 605 LC-SGGVCINTDGSFLCDCDAGF--------------EPSEDG---TDCIDRRTGTCYRS 646
C +GG C + + CDC GF +P +G TDC+D T TC
Sbjct: 917 -CHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAG 975
Query: 647 LVSGRCE 653
CE
Sbjct: 976 FSGIHCE 982
Score = 223 bits (544), Expect = 3e-57
Identities = 180/586 (30%), Positives = 261/586 (44%), Gaps = 89/586 (15%)
Query: 65 TKPIDECDIMPQLCK-PGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGM 123
T+ +DEC +MP C+ GTCH+T G+ C C +G+ ++ S ++D+C+ C
Sbjct: 293 TEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCS---ENIDDCA--SAACFHG 347
Query: 124 AQCVNLPGAFECRCPPGYR-LTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY 182
A C + +F C CP G L L++ + C + CD G C C GY
Sbjct: 348 ATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVN---GKAICTCPSGY 404
Query: 183 TLRENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGM 241
T +DVDECS C + G C N G++ C C G+ GP + +DVNEC
Sbjct: 405 T-GPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY-TGPRCE-IDVNECVSN-- 459
Query: 242 VCRN-GRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGG 299
C+N C + +G F+C C PGY +G +C + DEC PC +G C +
Sbjct: 460 PCQNDATCLDQIGEFQCMCMPGY----EGVHCEVNTDEC--ASSPCLHNGR--CLDKINE 511
Query: 300 YECSCGAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVC 357
++C C G+ G C D DEC P C G +C + Y C C G+ T C
Sbjct: 512 FQCECPTGF--TGHLCQYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGY----TGTHC 563
Query: 358 VDERKELCYDEWEAGRCHRARPLQ-LARPECCCSEGAAWGRYCE---------------R 401
E+ DE + CH +A C C G G +CE
Sbjct: 564 -----EVDIDECDPDPCHYGSCKDGVATFTCLCRPGYT-GHHCETNINECSSQPCRLRGT 617
Query: 402 CPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAP 461
C PD+A ++ C G PN +LD+C P C G C++ + C C GY
Sbjct: 618 CQDPDNA-YLCFCLKGTTGPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPGYT--- 671
Query: 462 DGLSC-VDADECALDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRA 518
G C + DECA +P C N GTC + G+ C+C G+ D TC+ +V+EC
Sbjct: 672 -GSMCNSNIDECAGNP--CHNGGTCEDGINGFTCRCPEGY---HDPTCLSEVNEC-NSNP 724
Query: 519 SCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI--DECVQEPRVCPHACENVVGSYICKC 576
C ++ ++C C G++ G +C DI +EC P V C+++ +C C
Sbjct: 725 CVHGACRDSLNGYKCDCDPGWS----GTNC-DINNNECESNPCVNGGTCKDMTSGIVCTC 779
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDC 622
EG+ S P N +INEC L + G CI+ + C+C
Sbjct: 780 REGF---SGP----NCQTNINECASNPCL-NKGTCIDDVAGYKCNC 817
Score = 219 bits (536), Expect = 3e-56
Identities = 241/855 (28%), Positives = 337/855 (39%), Gaps = 139/855 (16%)
Query: 33 APCE---ACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPG-TCHDTPT 88
+PC+ C P G H C PG + E ID+C CK G C D
Sbjct: 225 SPCQNGGTCRPTGDVTHECAC--LPG-FTGQNCEEN--IDDCP--GNNCKNGGACVDGVN 277
Query: 89 GFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
+ C C + T C DVDEC C+ C N G + C C G+
Sbjct: 278 TYNCPCPPEW----TGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWT---GE 330
Query: 148 DECEDVDECGDQRICDHG-DCRNTIGSYRCECKPGYTLRENVCRDVDEC-SRPRPVCRNG 205
D E++D+C C HG C + + S+ CEC G T +C D C S P C G
Sbjct: 331 DCSENIDDCASAA-CFHGATCHDRVASFYCECPHGRT--GLLCHLNDACISNP---CNEG 384
Query: 206 T-CENLP--GAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTVGSFRCECAP 261
+ C+ P G +C C G+ GP DV+EC G C + G+C NT+GSF C+C
Sbjct: 385 SNCDTNPVNGKAICTCPSGY-TGPACS-QDVDECSLGANPCEHAGKCINTLGSFECQCLQ 442
Query: 262 GYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRD 319
GYT G C DV+EC + +PC D +C + G ++C C G++ G C V+ D
Sbjct: 443 GYT----GPRCEIDVNEC--VSNPCQNDA--TCLDQIGEFQCMCMPGYE--GVHCEVNTD 492
Query: 320 ECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARP 379
EC P + G C + + CECP G+ T +C +++ C
Sbjct: 493 ECASSPCL-HNGRCLDKINEFQCECPTGF----TGHLC----------QYDVDEC----- 532
Query: 380 LQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG 439
+ P C GA C P++ + +C G + D+DEC PD C
Sbjct: 533 --ASTP---CKNGAK----C--LDGPNT--YTCVCTEGYTGTHCEVDIDECD--PDPCHY 577
Query: 440 GRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICG-NGTCSNTRGGYECQCSP 497
G C + +F C C GY G C + +EC+ P C GTC + Y C C
Sbjct: 578 GSCKDGVATFTCLCRPGYT----GHHCETNINECSSQP--CRLRGTCQDPDNAYLCFCLK 631
Query: 498 GFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQ 556
G T GP+ +++D+CA + C + + C C GY G C +IDEC
Sbjct: 632 G-TTGPNCE-INLDDCASSPCD-SGTCLDKIDGYECACEPGYT----GSMCNSNIDECAG 684
Query: 557 EPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQ--EDLCSGGVCINT 614
P CE+ + + C+CPEGY + + N C N C D +G C
Sbjct: 685 NPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEV-NECNS-NPCVHGACRDSLNGYKCDCD 742
Query: 615 DGSFLCDCDAG-----FEPSEDGTDCIDRRTG---TCYRSLVSGRCEPEXXXXXXXXXXX 666
G +CD P +G C D +G TC C+
Sbjct: 743 PGWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNINECASNPCLN 802
Query: 667 XXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXX 726
V +C C L G+ CE+ AP +P+ C
Sbjct: 803 KGTCIDD------VAGYKCNCLLPYT-GATCEVVLAPCAPSP---CRNGGEC-RQSEDYE 851
Query: 727 XXXXXXXXXXXXXXXLDVFADVDECAAIP----GLC--APGRFRCVCGPGYRPAGEVC-A 779
+V D++EC P C G +RC C GY +G C
Sbjct: 852 SFSCVCPTAGAKGQTCEV--DINECVLSPCRHGASCQNTHGXYRCHCQAGY--SGRNCET 907
Query: 780 DVDECAVRPPPCDQLCHNTDG--SYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQIC 836
D+D+C RP PC TDG + C C G+ G C D++EC D C
Sbjct: 908 DIDDC--RPNPCHNGGSCTDGINTAFCDCLPGFR----GTFCEEDINECASDPCRNGANC 961
Query: 837 SNTEGSYECSCEDGY 851
++ SY C+C G+
Sbjct: 962 TDCVDSYTCTCPAGF 976
Score = 209 bits (511), Expect = 3e-53
Identities = 201/677 (29%), Positives = 282/677 (41%), Gaps = 107/677 (15%)
Query: 20 KYLCCCSVGHAWGAPC----EACPPRGSPA-HTALCGEKPGEY-INPVTNETKPIDECDI 73
K +C C G+ G C + C +P H C G + + T P E D+
Sbjct: 395 KAICTCPSGYT-GPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDV 453
Query: 74 MPQLCKP----GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
+ P TC D FQC C GYE H + DEC+ PC +C++
Sbjct: 454 NECVSNPCQNDATCLDQIGEFQCMCMPGYEG---VHCEVNTDECA--SSPCLHNGRCLDK 508
Query: 130 PGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENV 188
F+C CP G+ T L C+ DVDEC + C + +Y C C GYT
Sbjct: 509 INEFQCECPTGF--TGHL--CQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTH-- 562
Query: 189 CR-DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVCR-N 245
C D+DEC P P C G+C++ + C C G+ + C ++NEC CR
Sbjct: 563 CEVDIDECD-PDP-CHYGSCKDGVATFTCLCRPGYTG---HHCETNINEC--SSQPCRLR 615
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
G C++ ++ C C G T G NC ++D+C P G +C + GYEC+C
Sbjct: 616 GTCQDPDNAYLCFCLKGTT----GPNCEINLDDCASSPCDSG-----TCLDKIDGYECAC 666
Query: 305 GAGWKLVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
G+ G C DEC P C GG C + G+ C CP G+ D T C+ E
Sbjct: 667 EPGY--TGSMCNSNIDECAGNP--CHNGGTCEDGINGFTCRCPEGYH-DPT---CLSEVN 718
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCSEGAAW------GRYCERCPAPD-------SAE 409
E + G C + L +C C G + CE P + ++
Sbjct: 719 ECNSNPCVHGACRDS----LNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSG 774
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSC-V 467
+ C+ G PN +++EC P C+ G C++ ++C C +L G +C V
Sbjct: 775 IVCTCREGFSGPNCQTNINECASNP--CLNKGTCIDDVAGYKCNC----LLPYTGATCEV 828
Query: 468 DADECALDPRICGNG-TCSNTRG--GYECQCSPGFTQGPDQTC-VDVDECAEGRASCTFR 523
CA P C NG C + + C C +G QTC VD++EC
Sbjct: 829 VLAPCAPSP--CRNGGECRQSEDYESFSCVCPTAGAKG--QTCEVDINECVLSPCRHGAS 884
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRR 582
C NT G +RC C GY+ G +C DID+C P +C + + + C C G+R
Sbjct: 885 CQNTHGXYRCHCQAGYS----GRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRG 940
Query: 583 TSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLCDCDAGFE--PSEDGT-DCIDR 638
T EDINEC D C G C + S+ C C AGF E+ T DC +
Sbjct: 941 TFCE-------EDINECAS--DPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTES 991
Query: 639 ---RTGTCYRSLVSGRC 652
GTC + S C
Sbjct: 992 SCFNGGTCVDGINSFTC 1008
Score = 206 bits (502), Expect = 3e-52
Identities = 193/677 (28%), Positives = 275/677 (40%), Gaps = 94/677 (13%)
Query: 19 TKYLCCCSVGHAWGAPCE---ACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMP 75
T +C ++ G PC C G T C P Y +P ++EC+ P
Sbjct: 671 TGSMCNSNIDECAGNPCHNGGTCED-GINGFTCRC---PEGYHDPTC--LSEVNECNSNP 724
Query: 76 QLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC 135
C G C D+ G++C CD G+ N C D++ PC C ++ C
Sbjct: 725 --CVHGACRDSLNGYKCDCDPGWSGTN----C-DINNNECESNPCVNGGTCKDMTSGIVC 777
Query: 136 RCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDE 194
C G+ S C+ +++EC + G C + + Y+C C YT C V
Sbjct: 778 TCREGF----SGPNCQTNINECASNPCLNKGTCIDDVAGYKCNCLLPYT--GATCEVVLA 831
Query: 195 CSRPRPVCRNG-TCENLPG--AYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CRN 250
P P CRNG C ++ C C G + VD+NEC CR+G C+N
Sbjct: 832 PCAPSP-CRNGGECRQSEDYESFSCVCPTAGAKGQTCE-VDINECVLSP--CRHGASCQN 887
Query: 251 TVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
T G +RC C GY+ GRNC D+D+C P+PC G SCT+ C C G++
Sbjct: 888 THGXYRCHCQAGYS----GRNCETDIDDCR--PNPCHNGG--SCTDGINTAFCDCLPGFR 939
Query: 310 LVGRRCV-DRDECKELPYVCAGG-ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYD 367
G C D +EC P C G C + Y C CPAG+ D + C++
Sbjct: 940 --GTFCEEDINECASDP--CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFN 995
Query: 368 EWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP-DSAEFMR--ICQGGMGR---- 420
G C + C C G G YC+ DS + CQ G G
Sbjct: 996 ---GGTCVDG----INSFTCLCPPGFT-GSYCQHVVNECDSRPCLLGGTCQDGRGLHRCT 1047
Query: 421 -------PNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYV-LAPD--GLSC-VD 468
PN + C P C GG+C T +RCECP G+ L D +SC V
Sbjct: 1048 CPQGYTGPNCQNLVHWCDSSP--CKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVA 1105
Query: 469 ADECALD-PRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCH 525
A +D R+C +G C + + C+C G+T C D VDEC+ C
Sbjct: 1106 AQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT---GSYCEDLVDECSPSPCQNGATCT 1162
Query: 526 NTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
+ G + C C GY GV+C +IDEC+ P C ++ +Y C CP G +
Sbjct: 1163 DYLGGYSCKCVAGY----HGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVH 1218
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF--EPSE-DGTDCID---- 637
+ ++ ++ + G C++ G + C C GF E E D +C+
Sbjct: 1219 CEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCD 1278
Query: 638 -RRTGTCYRSLVSGRCE 653
R T C + + CE
Sbjct: 1279 ARGTQNCVQRVNDFHCE 1295
Score = 186 bits (453), Expect = 3e-46
Identities = 191/623 (30%), Positives = 258/623 (41%), Gaps = 108/623 (17%)
Query: 60 PVTNETKPIDECDIMPQLCKPG-TCHDTPT--GFQCGCDHGYEHDNTSHLCRDVDECSWG 116
P T T + P C+ G C + F C C T + D++EC
Sbjct: 820 PYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTAGAKGQTCEV--DINECVLS 877
Query: 117 RPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYR 175
PCR A C N G + C C GY S CE D+D+C + G C + I +
Sbjct: 878 --PCRHGASCQNTHGXYRCHCQAGY----SGRNCETDIDDCRPNPCHNGGSCTDGINTAF 931
Query: 176 CECKPGYTLRENVCR-DVDECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVDV 233
C+C PG+ R C D++EC+ CRNG C + +Y C C GF + +
Sbjct: 932 CDCLPGF--RGTFCEEDINECASDP--CRNGANCTDCVDSYTCTCPAGFSGIHCEN--NT 985
Query: 234 NECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRDV-DECDELPHPCGRDGNP 291
+C E C NG C + + SF C C PG+T G C+ V +ECD PC G
Sbjct: 986 PDCTESS--CFNGGTCVDGINSFTCLCPPGFT----GSYCQHVVNECDS--RPCLLGG-- 1035
Query: 292 SCTNTNGGYECSCGAGWKLVGRRCVDRDE-CKELPYVCA-GGECRNFNGGYVCECPAGWR 349
+C + G + C+C G+ G C + C P C GG+C + Y CECP+GW
Sbjct: 1036 TCQDGRGLHRCTCPQGY--TGPNCQNLVHWCDSSP--CKNGGKCWQTHTQYRCECPSGW- 1090
Query: 350 FDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAE 409
T C D C E A R + + +AR C G C +
Sbjct: 1091 ---TGLYC-DVPSVSC--EVAAQR----QGVDVAR---LCQHGGL-------CVDAGNTH 1130
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVD 468
R CQ G +DEC P C G C + G + C+C GY G++C +
Sbjct: 1131 HCR-CQAGYTGSYCEDLVDECS--PSPCQNGATCTDYLGGYSCKCVAGY----HGVNCSE 1183
Query: 469 A-DECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAE-----GRASCT 521
DEC P C NG TC + Y+C C G TQG ++VD+C R+
Sbjct: 1184 EIDECLSHP--CQNGGTCLDLPNTYKCSCPRG-TQGVHCE-INVDDCNPPVDPVSRSPKC 1239
Query: 522 FR---CHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVC--PHACENVVGSYICK 575
F C + G + CTCP G+ G C D++EC+ P C V + C+
Sbjct: 1240 FNNGTCVDQVGGYSCTCPPGFV----GERCEGDVNECLSNPCDARGTQNCVQRVNDFHCE 1295
Query: 576 CPEGYRRTSAPQDSENACED-INECEEQEDLC-SGGVCI---NTDGSFLCDCDAGFEPSE 630
C G+ + CE IN C+ + C +GG C NT F+C C AGFE
Sbjct: 1296 CRAGH--------TGRRCESVINGCKGKP--CKNGGTCAVASNTARGFICKCPAGFE--- 1342
Query: 631 DGTDC-IDRRTGTCYRSLVSGRC 652
G C D RT R L G C
Sbjct: 1343 -GATCENDARTCGSLRCLNGGTC 1364
Score = 186 bits (452), Expect = 4e-46
Identities = 155/463 (33%), Positives = 190/463 (41%), Gaps = 73/463 (15%)
Query: 195 CSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRC---- 248
CS+P C NG CE G C C F GP C D N C C+N G C
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAF-VGPR--CQDPNPCLS--TPCKNAGTCHVVD 78
Query: 249 RNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
R V + C CA G++ G C + L +PC R+G T Y+C C GW
Sbjct: 79 RRGVADYACSCALGFS----GPLCLTPLDNACLTNPC-RNGGTCDLLTLTEYKCRCPPGW 133
Query: 309 KLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDE---RKEL 364
G+ C D C P CA GG+C F Y+C CP + T V+E + L
Sbjct: 134 S--GKSCQQADPCASNP--CANGGQCLPFEASYICHCPPSFH-GPTCRQDVNECGQKPRL 188
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQ-GGMGRP-- 421
C G CH ++ C C G CER P S CQ GG RP
Sbjct: 189 CR---HGGTCHN----EVGSYRCVC-RATHTGPNCERPYVPCSPS---PCQNGGTCRPTG 237
Query: 422 NLTQDL--------DECRVRPDVCVGGRCVN----TDG--SFRCECPDGYVLAPDGLSCV 467
++T + C D C G C N DG ++ C CP + G C
Sbjct: 238 DVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCPPEWT----GQYCT 293
Query: 468 -DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
D DEC L P C NG TC NT GGY C C G+T G D ++D+CA CH
Sbjct: 294 EDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWT-GED-CSENIDDCASAACFHGATCH 351
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN--VVGSYICKCPEGYRRT 583
+ SF C CP+G G+ C D C+ P C+ V G IC CP GY
Sbjct: 352 DRVASFYCECPHG----RTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGP 407
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
+ QD + N CE G CINT GSF C C G+
Sbjct: 408 ACSQDVDECSLGANPCEH------AGKCINTLGSFECQCLQGY 444
Score = 149 bits (360), Expect = 5e-35
Identities = 174/639 (27%), Positives = 245/639 (38%), Gaps = 99/639 (15%)
Query: 21 YLCCCSVGHAWGAPCEACPPRG--SPA-HTALCGEKPGEYINPVT------NETKPIDEC 71
+ C C A G CE SP H A C G Y N ID+C
Sbjct: 853 FSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAGYSGRNCETDIDDC 912
Query: 72 DIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNL 129
P C G+C D C C G+ C D++EC+ PCR A C +
Sbjct: 913 --RPNPCHNGGSCTDGINTAFCDCLPGFR----GTFCEEDINECA--SDPCRNGANCTDC 964
Query: 130 PGAFECRCPPGYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENV 188
++ C CP G+ S CE+ +C + + G C + I S+ C C PG+T +
Sbjct: 965 VDSYTCTCPAGF----SGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT--GSY 1018
Query: 189 CRDV-DECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG- 246
C+ V +EC RP GTC++ G + C C G+ GPN + V+ C C+NG
Sbjct: 1019 CQHVVNECDS-RPCLLGGTCQDGRGLHRCTCPQGY-TGPNCQNL-VHWCDSSP--CKNGG 1073
Query: 247 RCRNTVGSFRCECAPGYT-LTAD--GRNCRDVDECD--ELPHPCGRDGNPSCTNTNGGYE 301
+C T +RCEC G+T L D +C + ++ C G C + +
Sbjct: 1074 KCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGG--LCVDAGNTHH 1131
Query: 302 CSCGAGWKLVGRRCVDR-DECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVD 359
C C AG+ G C D DEC P C G C ++ GGY C+C AG+ C +
Sbjct: 1132 CRCQAGY--TGSYCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVAGYH----GVNCSE 1183
Query: 360 ERKE-LCYDEWEAGRCHRARPLQLARP-ECCCSEGAAWGRYCERCPAPDSAEFMRICQGG 417
E E L + G C L L +C C G G +CE
Sbjct: 1184 EIDECLSHPCQNGGTC-----LDLPNTYKCSCPRGTQ-GVHCE----------------- 1220
Query: 418 MGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDP 476
+ + +D P G CV+ G + C CP G+V G C D +EC +P
Sbjct: 1221 INVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV----GERCEGDVNECLSNP 1276
Query: 477 -RICGNGTCSNTRGGYECQCSPGFTQGPDQTCVD---VDECAEGRASCTFRCHNTAGSFR 532
G C + C+C G T ++ ++ C G +C NTA F
Sbjct: 1277 CDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNG-GTCAV-ASNTARGFI 1334
Query: 533 CTCPYGY--------AVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
C CP G+ A + C + C+ PR C C+ P
Sbjct: 1335 CKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLG 1394
Query: 585 A-PQDSENACEDINECEEQEDLC----SGGVCINTDGSF 618
P ++ CE +E LC +G +C D SF
Sbjct: 1395 GNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSF 1433
Score = 100 bits (239), Expect = 3e-20
Identities = 105/362 (29%), Positives = 144/362 (39%), Gaps = 54/362 (14%)
Query: 321 CKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARP 379
C + C GG+C NG C C G F C D L AG CH
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVC--GGAF--VGPRCQDPNPCLSTPCKNAGTCHVVDR 79
Query: 380 LQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP----- 434
+A C C+ G + G C D+A C+ G LT +CR P
Sbjct: 80 RGVADYACSCALGFS-GPLC--LTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGK 136
Query: 435 -----DVCV------GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNG 482
D C GG+C+ + S+ C CP + G +C D +EC PR+C +G
Sbjct: 137 SCQQADPCASNPCANGGQCLPFEASYICHCPPSF----HGPTCRQDVNECGQKPRLCRHG 192
Query: 483 -TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAG-SFRCTCPYGYA 540
TC N G Y C C T GP+ V C+ C T + C C G+
Sbjct: 193 GTCHNEVGSYRCVCRATHT-GPNCERPYVP-CSPSPCQNGGTCRPTGDVTHECACLPGFT 250
Query: 541 VAADGVHCRD-IDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENAC-EDINE 598
G +C + ID+C AC + V +Y C CP P+ + C ED++E
Sbjct: 251 ----GQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCP--------PEWTGQYCTEDVDE 298
Query: 599 CEEQEDLC-SGGVCINTDGSFLCDCDAGF---EPSEDGTDCIDR---RTGTCYRSLVSGR 651
C+ + C +GG C NT G + C C G+ + SE+ DC TC+ + S
Sbjct: 299 CQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFY 358
Query: 652 CE 653
CE
Sbjct: 359 CE 360
Score = 66.5 bits (155), Expect = 4e-10
Identities = 72/263 (27%), Positives = 96/263 (36%), Gaps = 35/263 (13%)
Query: 67 PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
P+D P+ GTC D G+ C C G+ + DV+EC RG C
Sbjct: 1229 PVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE---GDVNECLSNPCDARGTQNC 1285
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDV-DECGDQRICDHGDC---RNTIGSYRCECKPGY 182
V F C C G+ + CE V + C + + G C NT + C+C G+
Sbjct: 1286 VQRVNDFHCECRAGH----TGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGF 1341
Query: 183 TLRENVC-RDVDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGG 240
C D C R C N GTC + P + C C F GP + C G
Sbjct: 1342 --EGATCENDARTCGSLR--CLNGGTCISGPRSPTCLCLGPF-TGPECQFPASSPCLGGN 1396
Query: 241 MVCRNGRCRNTVGS--FRCECAPGYT--------LTADGRNCRD-----VDECDELPHPC 285
G C T S +RC C + + G RD ++E ELP C
Sbjct: 1397 PCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPE-C 1455
Query: 286 GRD-GNPSCTNTNGGYECSCGAG 307
D GN C+ + C G
Sbjct: 1456 QEDAGNKVCSLQCNNHACGWDGG 1478
Score = 65.3 bits (152), Expect = 9e-10
Identities = 36/96 (37%), Positives = 48/96 (50%), Gaps = 10/96 (10%)
Query: 761 GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDEDGA 817
G+ C C GY G C+ DVDEC++ PC+ C NT GS++C C GY G
Sbjct: 394 GKAICTCPSGY--TGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYT----GP 447
Query: 818 NCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
C DV+EC + C + G ++C C GYE
Sbjct: 448 RCEIDVNECVSNPCQNDATCLDQIGEFQCMCMPGYE 483
Score = 60.1 bits (139), Expect = 3e-08
Identities = 43/112 (38%), Positives = 50/112 (44%), Gaps = 18/112 (16%)
Query: 747 DVDECAAIPGLC--APGRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTD--GS 801
DV GLC A C C GY G C D VDEC+ P PC TD G
Sbjct: 1112 DVARLCQHGGLCVDAGNTHHCRCQAGY--TGSYCEDLVDECS--PSPCQNGATCTDYLGG 1167
Query: 802 YDCLCRTGYELDEDGANC-RDVDECERDTHTCQQ--ICSNTEGSYECSCEDG 850
Y C C GY G NC ++DEC +H CQ C + +Y+CSC G
Sbjct: 1168 YSCKCVAGYH----GVNCSEEIDECL--SHPCQNGGTCLDLPNTYKCSCPRG 1213
Score = 56.4 bits (130), Expect = 4e-07
Identities = 33/98 (33%), Positives = 45/98 (45%), Gaps = 9/98 (9%)
Query: 763 FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F CVC P G+ C D++EC + P C NT G Y C C+ GY G NC
Sbjct: 853 FSCVC-PTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAGY----SGRNCET 907
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
D+D+C + C++ + C C G+ RG C
Sbjct: 908 DIDDCRPNPCHNGGSCTDGINTAFCDCLPGF--RGTFC 943
Score = 54.0 bits (124), Expect = 2e-06
Identities = 30/88 (34%), Positives = 40/88 (45%), Gaps = 9/88 (10%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 821
++C C PG+ +G+ C D CA P C + SY C C + G CR D
Sbjct: 125 YKCRCPPGW--SGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFH----GPTCRQD 178
Query: 822 VDECERDTHTCQQ--ICSNTEGSYECSC 847
V+EC + C+ C N GSY C C
Sbjct: 179 VNECGQKPRLCRHGGTCHNEVGSYRCVC 206
Score = 50.8 bits (116), Expect = 2e-05
Identities = 38/114 (33%), Positives = 50/114 (43%), Gaps = 17/114 (14%)
Query: 749 DECAAIP----GLCAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTD 799
D CA+ P G C P + C C P + G C DV+EC +P C CHN
Sbjct: 142 DPCASNPCANGGQCLPFEASYICHCPPSFH--GPTCRQDVNECGQKPRLCRHGGTCHNEV 199
Query: 800 GSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNT-EGSYECSCEDGY 851
GSY C+CR + G NC R C C T + ++EC+C G+
Sbjct: 200 GSYRCVCRATH----TGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGF 249
Score = 50.0 bits (114), Expect = 4e-05
Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 15/110 (13%)
Query: 756 GLCAPG---RFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYE 811
G C P C C PG+ G+ C + +D+C C + +Y+C C +
Sbjct: 231 GTCRPTGDVTHECACLPGF--TGQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCPPEWT 288
Query: 812 LDEDGANC-RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
G C DVDEC+ + CQ C NT G Y C C +G+ G+ C
Sbjct: 289 ----GQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW--TGEDC 332
Score = 49.6 bits (113), Expect = 5e-05
Identities = 32/100 (32%), Positives = 41/100 (41%), Gaps = 10/100 (10%)
Query: 756 GLCAPG--RFRCVCGPGYRPAGEVCADV-DECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G C G F C+C PG+ G C V +EC RP C + G + C C GY
Sbjct: 997 GTCVDGINSFTCLCPPGF--TGSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGY-- 1052
Query: 813 DEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
G NC++ V C+ C T Y C C G+
Sbjct: 1053 --TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGW 1090
Score = 46.4 bits (105), Expect = 4e-04
Identities = 34/102 (33%), Positives = 46/102 (45%), Gaps = 19/102 (18%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCD----QLCHNTDGSYDCLCRTGYELDED 815
G + C C PG+ GE C DV+EC P CD Q C + C CR G+
Sbjct: 1250 GGYSCTCPPGF--VGERCEGDVNECLSNP--CDARGTQNCVQRVNDFHCECRAGHT---- 1301
Query: 816 GANCRDV-DECE----RDTHTCQQICSNTEGSYECSCEDGYE 852
G C V + C+ ++ TC + SNT + C C G+E
Sbjct: 1302 GRRCESVINGCKGKPCKNGGTCA-VASNTARGFICKCPAGFE 1342
Score = 45.6 bits (103), Expect = 8e-04
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 19/123 (15%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHN 797
DVDEC +P C G + CVC G+ GE C++ +D+CA CH+
Sbjct: 295 DVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW--TGEDCSENIDDCASAACFHGATCHD 352
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSN--TEGSYECSCEDGYEKRG 855
S+ C C G G C D C + C G C+C GY G
Sbjct: 353 RVASFYCECPHG----RTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGY--TG 406
Query: 856 DAC 858
AC
Sbjct: 407 PAC 409
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/129 (27%), Positives = 52/129 (40%), Gaps = 24/129 (18%)
Query: 748 VDECAAIP----GLCAP--GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDG 800
VDEC+ P C G + C C GY G C++ +DEC P C +
Sbjct: 1147 VDECSPSPCQNGATCTDYLGGYSCKCVAGYH--GVNCSEEIDECLSHPCQNGGTCLDLPN 1204
Query: 801 SYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQ--------ICSNTEGSYECSCEDGY 851
+Y C C G + G +C +VD+C + C + G Y C+C G+
Sbjct: 1205 TYKCSCPRGTQ----GVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGF 1260
Query: 852 EKRGDACVG 860
G+ C G
Sbjct: 1261 V--GERCEG 1267
Score = 40.3 bits (90), Expect = 0.028
Identities = 32/113 (28%), Positives = 46/113 (40%), Gaps = 19/113 (16%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCH 796
DV+EC P LC G +RCVC + G C + P PC C
Sbjct: 178 DVNECGQKPRLCRHGGTCHNEVGSYRCVCRATH--TGPNC-ERPYVPCSPSPCQNGGTCR 234
Query: 797 NT-DGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSC 847
T D +++C C G+ G NC + +D+C + C + +Y C C
Sbjct: 235 PTGDVTHECACLPGF----TGQNCEENIDDCPGNNCKNGGACVDGVNTYNCPC 283
Score = 39.9 bits (89), Expect = 0.038
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 5/59 (8%)
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
LC + ++ C C+ GY G+ C D VDEC C++ G Y C C GY
Sbjct: 1122 LCVDAGNTHHCRCQAGYT----GSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY 1176
Score = 31.9 bits (69), Expect = 10.0
Identities = 26/99 (26%), Positives = 36/99 (36%), Gaps = 11/99 (11%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHN-TDGSYDCLCRTGYELDEDGANC 819
+ C C G+ +G +C + A PC C T Y C C G+ G +C
Sbjct: 85 YACSCALGF--SGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWS----GKSC 138
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
+ D C + C E SY C C + G C
Sbjct: 139 QQADPCASNPCANGGQCLPFEASYICHCPPSF--HGPTC 175
>AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant
protein.
Length = 1289
Score = 237 bits (581), Expect = 9e-62
Identities = 243/833 (29%), Positives = 320/833 (38%), Gaps = 128/833 (15%)
Query: 68 IDECDIMPQLCKP-GTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQ 125
+DEC I C+ G C +T F C C GY T C DV+EC G PCR A
Sbjct: 395 VDECSIGANPCEHLGRCVNTQGSFLCQCGRGY----TGPRCETDVNECLSG--PCRNQAT 448
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
C++ G F C C G+ T CE D+DEC + G C++ + + C C G++
Sbjct: 449 CLDRIGQFTCICMAGFTGT----YCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFS- 503
Query: 185 RENVCR-DVDECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMV 242
+ C+ DVDEC+ CRNG C + P Y C C +GF+ G D +V++C
Sbjct: 504 -GSTCQLDVDECASTP--CRNGAKCVDQPDGYECRCAEGFE-GTLCDR-NVDDCSPDP-- 556
Query: 243 CRNGRCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGGYE 301
C +GRC + + SF C CAPGYT G C VDEC PC G C + Y
Sbjct: 557 CHHGRCVDGIASFSCACAPGYT----GTRCESQVDECRS--QPCRHGGK--CLDLVDKYL 608
Query: 302 CSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
C C +G G C V+ D+C P C G CR+ Y C C G+ T +C E
Sbjct: 609 CRCPSG--TTGVNCEVNIDDCASNP--CTFGVCRDGINRYDCVCQPGF----TGPLCNVE 660
Query: 361 RKEL----------CYDEWEAGRC----HRARPLQLARPECCCSEGAAWGRYCERCPAPD 406
E C D RC PL L C E + G C P
Sbjct: 661 INECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHG-ICYDAPGG- 718
Query: 407 SAEFMRICQGGMGRPNLTQDL--DECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDG 463
F +C+ G P +Q L D C +P C GG C + F C CP G G
Sbjct: 719 ---FRCVCEPGWSGPRCSQSLARDACESQP--CRAGGTCSSDGMGFHCTCPPGV----QG 769
Query: 464 LSCVDADECALDPRICGNGTCSNTRGGYE-CQCSPGFTQGPDQTCVDVDECAEGRASCTF 522
C C +P G G C + G C C G+ D C G +
Sbjct: 770 RQCELLSPCTPNPCEHG-GRCESAPGQLPVCSCPQGWQ----------DPCLNGGS---- 814
Query: 523 RCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVC-PHACENVVGSYICKCPEGY 580
C + GSF C+C G+A G C RD+DEC+ P C P C + V S+ C CP GY
Sbjct: 815 -CQDGVGSFSCSCLPGFA----GPRCARDVDECLSNP--CGPGTCTDHVASFTCTCPPGY 867
Query: 581 RRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSE---DGTDCID 637
QD + +C +GG C++ SF C C G+ + + C+
Sbjct: 868 GGFHCEQD-------LPDCSPSSCF-NGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLS 919
Query: 638 R---RTGTCYRSLVSGRCEP-EXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAW 693
R G C + RC E G + C W
Sbjct: 920 RPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGW 979
Query: 694 -GSECELCPAPGSPARLDLCTAVN-LTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDEC 751
G C++ P A + + L +VD C
Sbjct: 980 SGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPC 1039
Query: 752 AAIP----GLCAP--GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDC 804
A P G C G + C C PGY G+ C D VDECA +P C + Y C
Sbjct: 1040 LAQPCQHGGTCRGYMGGYMCECLPGYN--GDNCEDDVDECASQPCQHGGSCIDLVARYLC 1097
Query: 805 LCRTGY-----ELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
C G E++ED +D R H C + G + C+C GY
Sbjct: 1098 SCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHN--GTCVDLVGGFRCTCPPGY 1148
Score = 222 bits (542), Expect = 5e-57
Identities = 185/590 (31%), Positives = 248/590 (42%), Gaps = 78/590 (13%)
Query: 81 GTCHDTPTG-FQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGA--FECRC 137
G C P+ C C G+ + C+ D C G RG+ Q + G F CRC
Sbjct: 56 GRCTQLPSREAACLCPPGWVGER----CQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 111
Query: 138 PPGYRLTPSLDECEDVDECGDQRICDHGD-CR-NTIGSYRCECKPGYTLRENVCR-DVDE 194
P G+R P +C D C C HG C G + C C PGY R CR DVDE
Sbjct: 112 PRGFR-GP---DCSLPDPCLSSP-CAHGARCSVGPDGRFLCSCPPGYQGRS--CRSDVDE 164
Query: 195 CSRPRPVCRNGTCENLPGAYLCHCDDGFKAGP--NNDCVDV--NECREGGMVCRNGRCRN 250
C P GTC N PG++ C C G+ GP N V + CR GG ++G
Sbjct: 165 CRVGEPCRHGGTCLNTPGSFRCQCPAGY-TGPLCENPAVPCAPSPCRNGGTCRQSGDL-- 221
Query: 251 TVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
++ C C PG+ +G+NC +VD+C H C G +C + Y C C W
Sbjct: 222 ---TYDCACLPGF----EGQNCEVNVDDCPG--HRCLNGG--TCVDGVNTYNCQCPPEW- 269
Query: 310 LVGRRCV-DRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYD 367
G+ C D DEC+ P C GG C N GG+ C C GW + + D +C+
Sbjct: 270 -TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCF- 327
Query: 368 EWEAGRCH-RARPLQLARPE-----CCCSEGAAWGRYCER---CPA-PDSAEFMRICQGG 417
CH R A P C + A C C P + + C G
Sbjct: 328 --HGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPG 385
Query: 418 MGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALD 475
QD+DEC + + C GRCVNT GSF C+C GY G C D +EC
Sbjct: 386 FTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYT----GPRCETDVNECLSG 441
Query: 476 PRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCT 534
P C N TC + G + C C GFT + VD+DEC C + F CT
Sbjct: 442 P--CRNQATCLDRIGQFTCICMAGFTGTYCE--VDIDECQSSPCVNGGVCKDRVNGFSCT 497
Query: 535 CPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENAC 593
CP G++ G C+ D+DEC P C + Y C+C EG+ T ++
Sbjct: 498 CPSGFS----GSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRN----- 548
Query: 594 EDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
+++C D C G C++ SF C C G+ + + + R+ C
Sbjct: 549 --VDDCSP--DPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPC 594
Score = 209 bits (510), Expect = 4e-53
Identities = 203/649 (31%), Positives = 267/649 (41%), Gaps = 109/649 (16%)
Query: 58 INPVTNET--KPIDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS 114
+N T E+ + ID+C +C G TCHD F C C G T LC D C
Sbjct: 306 VNGWTGESCSQNIDDC--ATAVCFHGATCHDRVASFYCACPMG----KTGLLCHLDDACV 359
Query: 115 WGRPPCRGMAQCVNLP--GAFECRCPPGYRLTPSLDECEDVDECG-DQRICDH-GDCRNT 170
PC A C P G C CPPG+ + D+ DVDEC C+H G C NT
Sbjct: 360 SN--PCHEDAICDTNPVNGRAICTCPPGFT-GGACDQ--DVDECSIGANPCEHLGRCVNT 414
Query: 171 IGSYRCECKPGYTLRENVCRDVDEC-SRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNN 228
GS+ C+C GYT DV+EC S P CRN TC + G + C C GF G
Sbjct: 415 QGSFLCQCGRGYT-GPRCETDVNECLSGP---CRNQATCLDRIGQFTCICMAGF-TGTYC 469
Query: 229 DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGR 287
+ VD++EC+ V G C++ V F C C G++ G C+ DVDEC P C R
Sbjct: 470 E-VDIDECQSSPCV-NGGVCKDRVNGFSCTCPSGFS----GSTCQLDVDECASTP--C-R 520
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRRCVDR--DECKELPYVCAGGECRNFNGGYVCECP 345
+G C + GYEC C G++ G C DR D+C P C G C + + C C
Sbjct: 521 NG-AKCVDQPDGYECRCAEGFE--GTLC-DRNVDDCSPDP--CHHGRCVDGIASFSCACA 574
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRC-HRARPLQLARPECCCSEGAAWGRYCE---- 400
G+ T C + DE + C H + L L C G CE
Sbjct: 575 PGY----TGTRCESQ-----VDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNID 625
Query: 401 RCPA-PDSAEFMR--------ICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFR 450
C + P + R +CQ G P +++EC P C GG CV+ + FR
Sbjct: 626 DCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSP--CGEGGSCVDGENGFR 683
Query: 451 CECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDV 510
C CP G L P L + CA +P C +G C + GG+ C C PG++ +
Sbjct: 684 CLCPPGS-LPP--LCLPPSHPCAHEP--CSHGICYDAPGGFRCVCEPGWSGPRCSQSLAR 738
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA--CENV 568
D C C + F CTCP G G C + C P C H CE+
Sbjct: 739 DACESQPCRAGGTCSSDGMGFHCTCPPG----VQGRQCELLSPCTPNP--CEHGGRCESA 792
Query: 569 VGSY-ICKCPEGYR----RTSAPQD--------------SENACEDINECEEQEDLCSGG 609
G +C CP+G++ + QD D++EC + C G
Sbjct: 793 PGQLPVCSCPQGWQDPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDEC--LSNPCGPG 850
Query: 610 VCINTDGSFLCDCD---AGFEPSEDGTDCIDR---RTGTCYRSLVSGRC 652
C + SF C C GF +D DC GTC + S C
Sbjct: 851 TCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSC 899
Score = 208 bits (508), Expect = 6e-53
Identities = 197/643 (30%), Positives = 270/643 (41%), Gaps = 112/643 (17%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCEACPP-RGSP-AHTALCGEKP-GEYIN--PVTNE 64
C +V ++ C C G G C P SP AH A C P G ++ P +
Sbjct: 96 CQSSVVAGTARFSCRCPRGFR-GPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQ 154
Query: 65 TKP----IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+ +DEC + GTC +TP F+C C GY T LC + PC
Sbjct: 155 GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY----TGPLCEN-PAVPCAPSPC 209
Query: 121 RGMAQCVNLPG-AFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCEC 178
R C ++C C PG+ CE +VD+C R + G C + + +Y C+C
Sbjct: 210 RNGGTCRQSGDLTYDCACLPGF----EGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQC 265
Query: 179 KPGYTLRENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECR 237
P +T + DVDEC C N GTC N G + C C +G+ + +D +C
Sbjct: 266 PPEWT-GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNID--DCA 322
Query: 238 EGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
VC +G C + V SF C C G T G C D C + +PC D
Sbjct: 323 TA--VCFHGATCHDRVASFYCACPMGKT----GLLCHLDDAC--VSNPCHEDAICDTNPV 374
Query: 297 NGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRFDKTA 354
NG C+C G+ G C D DEC C G C N G ++C+C G+ T
Sbjct: 375 NGRAICTCPPGF--TGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY----TG 428
Query: 355 AVCVDERKELCYDEWEAGRC-HRARPL-QLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
C E +E +G C ++A L ++ + C C G G YCE
Sbjct: 429 PRC-----ETDVNECLSGPCRNQATCLDRIGQFTCICMAGFT-GTYCE------------ 470
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDAD 470
D+DEC+ P CV GG C + F C CP G+ G +C +D D
Sbjct: 471 ------------VDIDECQSSP--CVNGGVCKDRVNGFSCTCPSGF----SGSTCQLDVD 512
Query: 471 ECALDPRICGNGT-CSNTRGGYECQCSPGFTQGPDQTCVD--VDECAEGRASCTFRCHNT 527
ECA P C NG C + GYEC+C+ GF + T D VD+C+ RC +
Sbjct: 513 ECASTP--CRNGAKCVDQPDGYECRCAEGF----EGTLCDRNVDDCSPDPCH-HGRCVDG 565
Query: 528 AGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTS 584
SF C C GY G C +DEC +P C H C ++V Y+C+CP G +
Sbjct: 566 IASFSCACAPGYT----GTRCESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSGTTGVN 619
Query: 585 APQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
CE +I++C C+ GVC + + C C GF
Sbjct: 620 --------CEVNIDDCASNP--CTFGVCRDGINRYDCVCQPGF 652
Score = 180 bits (439), Expect = 1e-44
Identities = 183/615 (29%), Positives = 256/615 (41%), Gaps = 119/615 (19%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSH-LCRDVDECSWGRPPCRGMAQCVNLPGAFECR 136
C G C+D P GF+C C+ G+ S L RD E PCR C + F C
Sbjct: 707 CSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQ----PCRAGGTCSSDGMGFHCT 762
Query: 137 CPPGYR------LTPSL-DECEDVDEC----GDQRIC-----------DHGDCRNTIGSY 174
CPPG + L+P + CE C G +C + G C++ +GS+
Sbjct: 763 CPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQDPCLNGGSCQDGVGSF 822
Query: 175 RCECKPGYTLRENVCRDVDEC-SRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDV 233
C C PG+ RDVDEC S P C GTC + ++ C C G+ G + D+
Sbjct: 823 SCSCLPGFA-GPRCARDVDECLSNP---CGPGTCTDHVASFTCTCPPGY--GGFHCEQDL 876
Query: 234 NECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNP 291
+C C NG C + V SF C C PGYT G +C+ + D C L PC G
Sbjct: 877 PDCSPSS--CFNGGTCVDGVNSFSCLCRPGYT----GAHCQHEADPC--LSRPCLHGG-- 926
Query: 292 SCTNTNGGYECSCGAGWKLVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCECPAGWR 349
C+ + G+ C+C + G +C D C P C GG C G Y C CP GW
Sbjct: 927 VCSAAHPGFRCTCLESF--TGPQCQTLVDWCSRQP--CQNGGRCVQ-TGAY-CLCPPGWS 980
Query: 350 ---FDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPD 406
D + C + ++ + + + + C C EG G +CE+ P
Sbjct: 981 GRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRT-GSHCEQEVDPC 1039
Query: 407 SAE--------------FMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRC 451
A+ +M C G N D+DEC +P C GG C++ + C
Sbjct: 1040 LAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQP--CQHGGSCIDLVARYLC 1097
Query: 452 ECPDGYVLAPDGLSC-VDADECA----LD--PRICGNGTCSNTRGGYECQCSPGFTQGPD 504
CP G + G+ C ++ D+C LD PR NGTC + GG+ C C PG+T
Sbjct: 1098 SCPPGTL----GVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT---G 1150
Query: 505 QTC-VDVDECAEG--RASCTFRC-HNTAGSFRCTCPYGYAVAADGVHCRDI-DECVQEPR 559
C D++EC G A+ T C + G FRC C G++ G C+ + C +P
Sbjct: 1151 LRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFS----GPRCQTVLSPCESQP- 1205
Query: 560 VCPHA--CENVVG-----SYICKCPEGYRRTSAPQDSENACEDI-NECEEQEDLCSGGV- 610
C H C G ++ C C + + P+ CE + C E + C GV
Sbjct: 1206 -CQHGGQCRPSPGPGGGLTFTCHCAQPF---WGPR-----CERVARSCRELQ--CPVGVP 1254
Query: 611 CINTDGSFLCDCDAG 625
C T C C G
Sbjct: 1255 CQQTPRGPRCACPPG 1269
Score = 176 bits (428), Expect = 3e-43
Identities = 189/663 (28%), Positives = 246/663 (37%), Gaps = 103/663 (15%)
Query: 236 CREGGMVCRNGRCRNTVG-SFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDG--NPS 292
C +G GRC C C PG+ G C+ D C PC G S
Sbjct: 46 CLDGSPCANGGRCTQLPSREAACLCPPGWV----GERCQLEDPCHS--GPCAGRGVCQSS 99
Query: 293 CTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECR-NFNGGYVCECPAGWRF 350
+ C C G++ G C D C P CA G C +G ++C CP G++
Sbjct: 100 VVAGTARFSCRCPRGFR--GPDCSLPDPCLSSP--CAHGARCSVGPDGRFLCSCPPGYQ- 154
Query: 351 DKTAAVCVDERK--ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSA 408
++ VDE + E C G C P C C G G CE P +
Sbjct: 155 GRSCRSDVDECRVGEPCR---HGGTCLNT-PGSF---RCQCPAGYT-GPLCENPAVPCAP 206
Query: 409 EFMRICQGGMGRPN--LTQDL--------DECRVRPDVCVGGRCVN----TDG--SFRCE 452
R GG R + LT D C V D C G RC+N DG ++ C+
Sbjct: 207 SPCR--NGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQ 264
Query: 453 CPDGYVLAPDGLSCV-DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDV 510
CP + G C D DEC L P C NG TC NT GG+ C C G+T + ++
Sbjct: 265 CPPEWT----GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTG--ESCSQNI 318
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN--V 568
D+CA CH+ SF C CP G G+ C D CV P C+ V
Sbjct: 319 DDCATAVCFHGATCHDRVASFYCACPMGKT----GLLCHLDDACVSNPCHEDAICDTNPV 374
Query: 569 VGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP 628
G IC CP G+ + QD + N CE G C+NT GSFLC C G+
Sbjct: 375 NGRAICTCPPGFTGGACDQDVDECSIGANPCEHL------GRCVNTQGSFLCQCGRGYTG 428
Query: 629 SEDGTD---CID---RRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTK 682
TD C+ R TC + C G V K
Sbjct: 429 PRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCK 488
Query: 683 AQ-----CCCTLGAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXX 737
+ C C G + GS C+L +D C + TP
Sbjct: 489 DRVNGFSCTCPSGFS-GSTCQL--------DVDECAS---TPCRNGAKCVDQPDGYECRC 536
Query: 738 XXXXLDVFAD--VDECAAIP---GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPP 789
D VD+C+ P G C G F C C PGY G C + VDEC +P
Sbjct: 537 AEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGY--TGTRCESQVDECRSQPC 594
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCE 848
C + Y C C +G G NC ++D+C + T +C + Y+C C+
Sbjct: 595 RHGGKCLDLVDKYLCRCPSG----TTGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQ 649
Query: 849 DGY 851
G+
Sbjct: 650 PGF 652
Score = 169 bits (411), Expect = 4e-41
Identities = 189/672 (28%), Positives = 265/672 (39%), Gaps = 122/672 (18%)
Query: 21 YLCCCSVGHAWGAPCEACPP--RGSPA-HTALCGEKPGEYINPVTNETKP------IDEC 71
+ C C+ G+ G CE+ R P H C + +Y+ + T ID+C
Sbjct: 569 FSCACAPGYT-GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDC 627
Query: 72 DIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLP 130
P C G C D + C C G+ T LC +++EC+ PC CV+
Sbjct: 628 ASNP--CTFGVCRDGINRYDCVCQPGF----TGPLCNVEINECA--SSPCGEGGSCVDGE 679
Query: 131 GAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYT---LREN 187
F C CPPG P L C C HG C + G +RC C+PG++ ++
Sbjct: 680 NGFRCLCPPGS--LPPL--CLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQS 735
Query: 188 VCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGPN---NDCVDVNECREGGM-- 241
+ RD E S+P CR GTC + + C C G + + C N C GG
Sbjct: 736 LARDACE-SQP---CRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTP-NPCEHGGRCE 790
Query: 242 -------VC-----------RNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPH 283
VC G C++ VGSF C C PG+ A R RDVDEC L +
Sbjct: 791 SAPGQLPVCSCPQGWQDPCLNGGSCQDGVGSFSCSCLPGF---AGPRCARDVDEC--LSN 845
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCE 343
PC G +CT+ + C+C G+ G C ++LP C+ C FNGG
Sbjct: 846 PC---GPGTCTDHVASFTCTCPPGYG--GFHCE-----QDLPD-CSPSSC--FNGG---T 889
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRC-HRARPLQLARPECCCSEGAAWGRYCERC 402
C G V+ LC + C H A P L+RP C G C
Sbjct: 890 CVDG----------VNSFSCLCRPGYTGAHCQHEADPC-LSRP---CLHGGV-------C 928
Query: 403 PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAP 461
A F C P +D C +P C GGRCV T G++ C CP G+
Sbjct: 929 SAAHPG-FRCTCLESFTGPQCQTLVDWCSRQP--CQNGGRCVQT-GAY-CLCPPGWSGRL 983
Query: 462 DGLSCVDADECALD-----PRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAE 515
+ + E A ++C G C + + C C G T + +VD C
Sbjct: 984 CDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQ--EVDPCLA 1041
Query: 516 GRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPH--ACENVVGSY 572
C G + C C GY +G +C D +DEC +P C H +C ++V Y
Sbjct: 1042 QPCQHGGTCRGYMGGYMCECLPGY----NGDNCEDDVDECASQP--CQHGGSCIDLVARY 1095
Query: 573 ICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDG 632
+C CP G + +E+ C + G C++ G F C C G+
Sbjct: 1096 LCSCPPGTLGVLC-EINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCE 1154
Query: 633 TDCIDRRTGTCY 644
D + R+G C+
Sbjct: 1155 ADINECRSGACH 1166
Score = 126 bits (303), Expect = 4e-28
Identities = 129/409 (31%), Positives = 167/409 (40%), Gaps = 54/409 (13%)
Query: 21 YLCCCSVGHAWGAPC--EACPPRGSPA-HTALCGEK-PGEYINPVTNETKPIDECDIMPQ 76
+ C C G+ GA C EA P P H +C PG + + T P +C +
Sbjct: 897 FSCLCRPGYT-GAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGP--QCQTLVD 953
Query: 77 LCKPGTCHD----TPTGFQCGCDHGYEH---DNTSHLCRDVDECSWGRPP--CRGMAQCV 127
C C + TG C C G+ D S CR+ R C+ QCV
Sbjct: 954 WCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCV 1013
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD-CRNTIGSYRCECKPGYTLRE 186
+ + C CP G T S E ++VD C Q C HG CR +G Y CEC PGY +
Sbjct: 1014 DEDSSHYCVCPEGR--TGSHCE-QEVDPCLAQP-CQHGGTCRGYMGGYMCECLPGYN-GD 1068
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG----PNNDCVDVNECREGGMV 242
N DVDEC+ +P G+C +L YLC C G +DC G
Sbjct: 1069 NCEDDVDECA-SQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRC 1127
Query: 243 CRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSC-TNTNGGY 300
NG C + VG FRC C PGYT G C D++EC C C + GG+
Sbjct: 1128 LHNGTCVDLVGGFRCTCPPGYT----GLRCEADINECRS--GACHAAHTRDCLQDPGGGF 1181
Query: 301 ECSCGAGWKLVGRRC-VDRDECKELPYVCA-GGECR---NFNGG--YVCECPA---GWRF 350
C C AG+ G RC C+ P C GG+CR GG + C C G R
Sbjct: 1182 RCLCHAGFS--GPRCQTVLSPCESQP--CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRC 1237
Query: 351 DKTAAVCVDERKEL---CYDEWEAGRCHRARPLQLARPECCCSEGAAWG 396
++ A C + + + C RC A P L+ P C G+ G
Sbjct: 1238 ERVARSCRELQCPVGVPCQQTPRGPRC--ACPPGLSGPSCRSFPGSPPG 1284
Score = 121 bits (291), Expect = 1e-26
Identities = 150/521 (28%), Positives = 196/521 (37%), Gaps = 88/521 (16%)
Query: 25 CSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCH 84
CS W PC + C PG + P + +DEC P C PGTC
Sbjct: 799 CSCPQGWQDPCLNGGSCQDGVGSFSCSCLPG-FAGPRC--ARDVDECLSNP--CGPGTCT 853
Query: 85 DTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLT 144
D F C C GY H +D+ +CS C CV+ +F C C PGY
Sbjct: 854 DHVASFTCTCPPGY---GGFHCEQDLPDCS--PSSCFNGGTCVDGVNSFSCLCRPGYTGA 908
Query: 145 PSLDECE-DVDECGDQRICDHGD-CRNTIGSYRCECKPGYTLRENVCRD-VDECSRPRPV 201
C+ + D C R C HG C +RC C +T + C+ VD CSR +P
Sbjct: 909 ----HCQHEADPCLS-RPCLHGGVCSAAHPGFRCTCLESFTGPQ--CQTLVDWCSR-QPC 960
Query: 202 CRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGG--------MVCR-NGRCRNTV 252
G C GAY C C G+ +G D + CRE +C+ G+C +
Sbjct: 961 QNGGRCVQT-GAY-CLCPPGW-SGRLCDIRSL-PCREAAAQIGVRLEQLCQAGGQCVDED 1016
Query: 253 GSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
S C C G T G +C ++VD C L PC G +C GGY C C G+
Sbjct: 1017 SSHYCVCPEGRT----GSHCEQEVDPC--LAQPCQHGG--TCRGYMGGYMCECLPGYN-- 1066
Query: 312 GRRCVDR-DECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYD-- 367
G C D DEC P C GG C + Y+C CP G T V + ++ C
Sbjct: 1067 GDNCEDDVDECASQP--CQHGGSCIDLVARYLCSCPPG-----TLGVLCEINEDDCGPGP 1119
Query: 368 EWEAG-RC-HRARPLQLA---RPEC--------C------CSEGAAWGRYCERCPAPDSA 408
++G RC H + L R C C C GA + C
Sbjct: 1120 PLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGG 1179
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDG-----SFRCECPDGYVLAPD 462
F +C G P L C +P C GG+C + G +F C C +
Sbjct: 1180 GFRCLCHAGFSGPRCQTVLSPCESQP--CQHGGQCRPSPGPGGGLTFTCHCAQPFW---- 1233
Query: 463 GLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
G C + + C T G C C PG + GP
Sbjct: 1234 GPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLS-GP 1273
Score = 59.3 bits (137), Expect = 6e-08
Identities = 36/114 (31%), Positives = 52/114 (45%), Gaps = 14/114 (12%)
Query: 747 DVDECAAIP----GLCAP--GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
DV+EC + P C G+F C+C G+ G C D+DEC P +C +
Sbjct: 434 DVNECLSGPCRNQATCLDRIGQFTCICMAGF--TGTYCEVDIDECQSSPCVNGGVCKDRV 491
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+ C C +G+ G+ C+ DVDEC C + YEC C +G+E
Sbjct: 492 NGFSCTCPSGFS----GSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFE 541
Score = 58.4 bits (135), Expect = 1e-07
Identities = 40/97 (41%), Positives = 52/97 (53%), Gaps = 12/97 (12%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY--ELDED 815
GRF C C PGY+ G C +DVDEC V PC C NT GS+ C C GY L E+
Sbjct: 143 GRFLCSCPPGYQ--GRSCRSDVDECRV-GEPCRHGGTCLNTPGSFRCQCPAGYTGPLCEN 199
Query: 816 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
A C R+ TC+Q + + +Y+C+C G+E
Sbjct: 200 PAVPCAPSPC-RNGGTCRQ---SGDLTYDCACLPGFE 232
Score = 53.2 bits (122), Expect = 4e-06
Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 14/109 (12%)
Query: 756 GLCAPG--RFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY 810
G C G + C C P + G+ C DVDEC ++P C C NT G + C+C G+
Sbjct: 252 GTCVDGVNTYNCQCPPEW--TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW 309
Query: 811 ELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
G +C +++D+C C + S+ C+C G K G C
Sbjct: 310 ----TGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMG--KTGLLC 352
Score = 52.8 bits (121), Expect = 5e-06
Identities = 32/117 (27%), Positives = 48/117 (41%), Gaps = 15/117 (12%)
Query: 747 DVDECAAIP----GLCAPGR--FRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDG 800
+++ECA+ P G C G FRC+C PG P +C P +C++ G
Sbjct: 660 EINECASSPCGEGGSCVDGENGFRCLCPPGSLPP--LCLPPSHPCAHEPCSHGICYDAPG 717
Query: 801 SYDCLCRTGYELDEDGANCRDV---DECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
+ C+C G+ G C D CE CS+ + C+C G + R
Sbjct: 718 GFRCVCEPGW----SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGR 770
Score = 45.6 bits (103), Expect = 8e-04
Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 12/103 (11%)
Query: 756 GLC--APGRFRCVCGPGYRPAGEVCADV---DECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
G+C APG FRCVC PG+ +G C+ D C +P C + + C C G
Sbjct: 710 GICYDAPGGFRCVCEPGW--SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGV 767
Query: 811 ELDEDGANCRDVDECERDTHTCQQICSNTEGSYE-CSCEDGYE 852
+ G C + C + C + G CSC G++
Sbjct: 768 Q----GRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQ 806
Score = 44.0 bits (99), Expect = 0.002
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 19/123 (15%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHN 797
DVDEC P C G CVC G+ GE C+ ++D+CA CH+
Sbjct: 277 DVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW--TGESCSQNIDDCATAVCFHGATCHD 334
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSN--TEGSYECSCEDGYEKRG 855
S+ C C G + G C D C + IC G C+C G+ G
Sbjct: 335 RVASFYCACPMG----KTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGF--TG 388
Query: 856 DAC 858
AC
Sbjct: 389 GAC 391
Score = 38.3 bits (85), Expect = 0.11
Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 11/95 (11%)
Query: 765 CVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNT----DGSYDCLCRTGYELDEDGANCR 820
C+C PG+ GE C D C P +C ++ + C C G+ G +C
Sbjct: 68 CLCPPGW--VGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFR----GPDCS 121
Query: 821 DVDECERDTHTCQQICS-NTEGSYECSCEDGYEKR 854
D C CS +G + CSC GY+ R
Sbjct: 122 LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGR 156
Score = 37.9 bits (84), Expect = 0.15
Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 13/78 (16%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDEC---AVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 816
G FRC C PGY G C AD++EC A + G + CLC G+ G
Sbjct: 1138 GGFRCTCPPGY--TGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGF----SG 1191
Query: 817 ANCRDV-DECERDTHTCQ 833
C+ V CE + CQ
Sbjct: 1192 PRCQTVLSPCE--SQPCQ 1207
>X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein.
Length = 1184
Score = 234 bits (573), Expect = 9e-61
Identities = 189/629 (30%), Positives = 253/629 (40%), Gaps = 86/629 (13%)
Query: 5 EEDQSCAGAVGVPQTKYLC-CCSVG---HAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
E++ SC G+ K C CC +G A G CE+ P G P + + GE
Sbjct: 505 EDNDSC----GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLI 560
Query: 61 VTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD-VDECSWGRPP 119
V +P + P + + G E + + L D DEC P
Sbjct: 561 VPEVRRPPEPA------AAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLL-LPG 613
Query: 120 CRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECK 179
C+N G++ C C PG+ L C ++
Sbjct: 614 ELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTI 673
Query: 180 PGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECRE 238
P + N C+D C + C + G+ +C C G+ + C D+NEC
Sbjct: 674 PLPLPQPNTCKDNGPCKQ--------VCSTVGGSAICSCFPGYAIMADGVSCEDINECVT 725
Query: 239 GGMVCRNGR-CRNTVGSFRC----ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
C G C NT+GSF C C PGY L DG C DVDEC H C C
Sbjct: 726 DLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK-DGE-CEDVDECAMGTHTC--QPGFLC 781
Query: 294 TNTNGGYECS----CGAGWKLVGR-RCVDRDECKELPYVCAGG-ECRNFNGGYVCE---- 343
NT G + C C G+ CVD +EC L C G C N G Y C+
Sbjct: 782 QNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPL 841
Query: 344 -CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERC 402
C G+ A CVD +E E G HR C EG + C
Sbjct: 842 ICARGYHASDDGAKCVD------VNECETG-VHR------------CGEG----QVCHNL 878
Query: 403 PAPDSAEFMRICQGGMGRPNLTQ---DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVL 459
P + C+ G R + D++EC P C NT GS+RC C G++L
Sbjct: 879 PGSYRCD----CKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLL 934
Query: 460 APDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRA 518
A DG C D +EC + + C C+N G Y+C C G+ D TC D+DECA+G
Sbjct: 935 AADGKRCEDVNEC--EAQRCSQ-ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAG 991
Query: 519 S-CTFRCHNTAGSFRCTCP-YGYAVAADGVHCRDIDECVQEPRVCPHA--CENVVGSYIC 574
CTFRC N GS++C CP GY + A+G C+D+DEC C A C N+ GS+ C
Sbjct: 992 ILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1051
Query: 575 ---KCPEGYRRTSAPQDSENACEDINECE 600
+CP Y + S + C D EC+
Sbjct: 1052 LRFECPPNYVQVSKTKCERTTCHDFLECQ 1080
Score = 225 bits (551), Expect = 4e-58
Identities = 163/490 (33%), Positives = 217/490 (44%), Gaps = 61/490 (12%)
Query: 151 EDVDECG--DQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGT 206
+D DEC +C H C NT+GSY C C PG++L+++ CR E P+P
Sbjct: 603 DDQDECLLLPGELCQHL-CINTVGSYHCACFPGFSLQDDGRTCRP--EGHPPQPEAPQEP 659
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLT 266
+ + N C D C++ C GS C C PGY +
Sbjct: 660 ALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQV--------CSTVGGSAICSCFPGYAIM 711
Query: 267 ADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC----SCGAGWKLVGRRCVDRDECK 322
ADG +C D++EC H C R + C NT G + C +C G+ L C D DEC
Sbjct: 712 ADGVSCEDINECVTDLHTCSRGEH--CVNTLGSFHCYKALTCEPGYALKDGECEDVDECA 769
Query: 323 ELPYVCAGGE-CRNFNGGYVCE----CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRA 377
+ C G C+N G + C+ C G+ D CVD + E
Sbjct: 770 MGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSE--------- 819
Query: 378 RPLQLARPECCCSEGAAWGRY-CERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDV 436
P RP C G Y C+R P + + G D++EC
Sbjct: 820 -P---CRPGFSCINTV--GSYTCQRNPLICARGYHASDDGAK-----CVDVNECETGVHR 868
Query: 437 CVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDP-RICGNGTCSNTRGGYECQ 494
C G+ C N GS+RC+C G+ G C+D +EC P R+C + TC NT G Y C
Sbjct: 869 CGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCS 927
Query: 495 CSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDE 553
C+ GF D + C DV+EC R C+ C N GS++C C GY +A DG C DIDE
Sbjct: 928 CASGFLLAADGKRCEDVNECEAQR--CSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDE 985
Query: 554 CVQEPRV-CPHACENVVGSYICKCPE-GYRRTSAPQDSENACEDINECEEQEDLCS-GGV 610
C Q + C C NV GSY C CPE GY T+ + +C+D++EC CS
Sbjct: 986 CAQGAGILCTFRCLNVPGSYQCACPEQGYTMTA----NGRSCKDVDECALGTHNCSEAET 1041
Query: 611 CINTDGSFLC 620
C N GSF C
Sbjct: 1042 CHNIQGSFRC 1051
Score = 217 bits (531), Expect = 1e-55
Identities = 168/529 (31%), Positives = 229/529 (43%), Gaps = 80/529 (15%)
Query: 69 DECDIMP-QLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
DEC ++P +LC+ C +T + C C G+ + CR G PP Q
Sbjct: 606 DECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPE-----GHPPQPEAPQEP 659
Query: 128 NLPGAFECRCPPGYRL-TPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
L F L P + C+D C +++C GS C C PGY +
Sbjct: 660 ALKSEFSQVASNTIPLPLPQPNTCKDNGPC--KQVCS-----TVGGSAICSCFPGYAIMA 712
Query: 187 N--VCRDVDECSRPRPVCRNGT-CENLPGAYLCH----CDDGFKAGPNNDCVDVNECREG 239
+ C D++EC C G C N G++ C+ C+ G+ A + +C DV+EC G
Sbjct: 713 DGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY-ALKDGECEDVDECAMG 771
Query: 240 GMVCRNG-RCRNTVGSFRCE----CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCT 294
C+ G C+NT GSF C+ C G+ +G NC D++EC L PC R G SC
Sbjct: 772 THTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPC-RPGF-SCI 828
Query: 295 NTNGGYECS-----CGAGWKLV--GRRCVDRDECKELPYVCAGGE-CRNFNGGYVCECPA 346
NT G Y C C G+ G +CVD +EC+ + C G+ C N G Y C+C A
Sbjct: 829 NTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKA 888
Query: 347 GWRFDKTAAVCVDERKELCYDEWEAGR-CHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
G++ D C+D + C+ GR C L C C+ G +RC
Sbjct: 889 GFQRDAFGRGCIDVNE--CWA--SPGRLCQHTCENTLGSYRCSCASGFLLAADGKRC--- 941
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
+D++EC + C C N GS++C C GY LA DG +
Sbjct: 942 -------------------EDVNECEAQR--C-SQECANIYGSYQCYCRQGYQLAEDGHT 979
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQC-SPGFTQGPD-QTCVDVDECAEGRASCT-- 521
C D DECA I C N G Y+C C G+T + ++C DVDECA G +C+
Sbjct: 980 CTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEA 1039
Query: 522 FRCHNTAGSFRC---TCPYGYA----VAADGVHCRDIDECVQEPRVCPH 563
CHN GSFRC CP Y + C D EC P H
Sbjct: 1040 ETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPARITH 1088
Score = 177 bits (431), Expect = 1e-43
Identities = 140/469 (29%), Positives = 203/469 (43%), Gaps = 69/469 (14%)
Query: 191 DVDECSR-PRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCR 249
D DEC P +C++ C N G+Y C C GF D CR G + +
Sbjct: 604 DQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQD-----DGRTCRPEGHPPQPEAPQ 657
Query: 250 NTVGSFRCECAPGYTLTA---DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
T+ C+D C ++ C+ G CSC
Sbjct: 658 EPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQV-----------CSTVGGSAICSCFP 706
Query: 307 GWKLV--GRRCVDRDECKELPYVCAGGE-CRNFNGGYVC----ECPAGWRFDKTAAVCVD 359
G+ ++ G C D +EC + C+ GE C N G + C C G+ VD
Sbjct: 707 GYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVD 766
Query: 360 ERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMG 419
E C A H +P L C ++G+ + + +RC D F++ +G
Sbjct: 767 E----C-----AMGTHTCQPGFL----CQNTKGSFYCQARQRCM--DG--FLQDPEGNC- 808
Query: 420 RPNLTQDLDECRVRPDVCVGG-RCVNTDGSFRCE-----CPDGYVLAPDGLSCVDADECA 473
D++EC + C G C+NT GS+ C+ C GY + DG CVD +EC
Sbjct: 809 -----VDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECE 863
Query: 474 LDPRICGNG-TCSNTRGGYECQCSPGFTQGP-DQTCVDVDEC--AEGRASCTFRCHNTAG 529
CG G C N G Y C C GF + + C+DV+EC + GR C C NT G
Sbjct: 864 TGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRL-CQHTCENTLG 922
Query: 530 SFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDS 589
S+RC+C G+ +AADG C D++EC E + C C N+ GSY C C +GY+ +
Sbjct: 923 SYRCSCASGFLLAADGKRCEDVNEC--EAQRCSQECANIYGSYQCYCRQGYQLA----ED 976
Query: 590 ENACEDINECEEQEDLCSGGVCINTDGSFLCDC-DAGFEPSEDGTDCID 637
+ C DI+EC + + C+N GS+ C C + G+ + +G C D
Sbjct: 977 GHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKD 1025
Score = 138 bits (335), Expect = 6e-32
Identities = 176/660 (26%), Positives = 232/660 (35%), Gaps = 117/660 (17%)
Query: 259 CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC--V 316
CA G D C ++ E + C C + C G G C
Sbjct: 446 CAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETCGAE 505
Query: 317 DRDECKELPYV----CAGGECRNFNGGYVCECPA--GWRFDKTAAVCVDERKELCYDEWE 370
D D C Y C G R G CE G+ + C + + L E
Sbjct: 506 DNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEVR 565
Query: 371 AGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDEC 430
A P +++ E E + G E P+S P D DEC
Sbjct: 566 RPPEPAAAPRRVSEAEMAGREALSLGTEAE---LPNSL------------PG--DDQDEC 608
Query: 431 RVRPDVCVGGRCVNTDGSFRCEC-------PDGYVLAPDG----------------LSCV 467
+ P C+NT GS+ C C DG P+G S V
Sbjct: 609 LLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQV 668
Query: 468 DADECAL---DPRIC-GNG----TCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRA 518
++ L P C NG CS G C C PG+ D +C D++EC
Sbjct: 669 ASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLH 728
Query: 519 SCTF--RCHNTAGSFRC----TCPYGYAVAADGVHCRDIDECVQEPRVCPHA--CENVVG 570
+C+ C NT GSF C TC GYA+ DG C D+DEC C C+N G
Sbjct: 729 TCSRGEHCVNTLGSFHCYKALTCEPGYALK-DG-ECEDVDECAMGTHTCQPGFLCQNTKG 786
Query: 571 SYIC----KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLCD---- 621
S+ C +C +G+ QD E C DINEC + C G CINT GS+ C
Sbjct: 787 SFYCQARQRCMDGFL-----QDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPL 841
Query: 622 -CDAGFEPSEDGTDCID--------RRTG---TCYRSLVSGRCEPEXXXXXXXXXXXXXX 669
C G+ S+DG C+D R G C+ S RC+ +
Sbjct: 842 ICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCID 901
Query: 670 XXXXXXXXGHVTKAQCCCTLGAAWGSECE---LCPAPGSPAR-LDLCTAVNLTPXXXXXX 725
G + + C TLG+ + C L A G ++ C A +
Sbjct: 902 VNECWASPGRLCQHTCENTLGS-YRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIY 960
Query: 726 XXXXXXXXXXXXXXXXLDVFADVDECAAIPG-LCA------PGRFRCVCGP-GYRPA--G 775
D+DECA G LC PG ++C C GY G
Sbjct: 961 GSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG 1020
Query: 776 EVCADVDECAVRPPPCDQL--CHNTDGSYDCL---CRTGY----ELDEDGANCRDVDECE 826
C DVDECA+ C + CHN GS+ CL C Y + + C D EC+
Sbjct: 1021 RSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQ 1080
Score = 97.1 bits (231), Expect = 2e-19
Identities = 53/116 (45%), Positives = 64/116 (55%), Gaps = 13/116 (11%)
Query: 747 DVDECAAIPG-LCAP------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
DV+EC A PG LC G +RC C G+ A G+ C DV+EC + C Q C N
Sbjct: 901 DVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQECAN 958
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTH-TCQQICSNTEGSYECSC-EDGY 851
GSY C CR GY+L EDG C D+DEC + C C N GSY+C+C E GY
Sbjct: 959 IYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGY 1014
Score = 94.3 bits (224), Expect = 2e-18
Identities = 46/100 (46%), Positives = 55/100 (55%), Gaps = 5/100 (5%)
Query: 760 PGRFRCVCGPGY-RPA-GEVCADVDECAVRPPP-CDQLCHNTDGSYDCLCRTGYELDEDG 816
PG +RC C G+ R A G C DV+EC P C C NT GSY C C +G+ L DG
Sbjct: 879 PGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADG 938
Query: 817 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C DV+ECE C Q C+N GSY+C C GY+ D
Sbjct: 939 KRCEDVNECE--AQRCSQECANIYGSYQCYCRQGYQLAED 976
Score = 87.0 bits (206), Expect = 3e-16
Identities = 53/138 (38%), Positives = 65/138 (47%), Gaps = 26/138 (18%)
Query: 747 DVDECAAIPGLCAPG--------------RFRCVCGPGYRPAGEVCADVDECAVRPPPCD 792
DVDECA C PG R RC+ G P G C D++EC PC
Sbjct: 764 DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCR 822
Query: 793 Q--LCHNTDGSYDC-----LCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSY 843
C NT GSY C +C GY +DGA C DV+ECE H C Q+C N GSY
Sbjct: 823 PGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSY 882
Query: 844 ECSCEDGYEKR--GDACV 859
C C+ G+++ G C+
Sbjct: 883 RCDCKAGFQRDAFGRGCI 900
Score = 87.0 bits (206), Expect = 3e-16
Identities = 47/124 (37%), Positives = 60/124 (48%), Gaps = 20/124 (16%)
Query: 747 DVDECAAIPGLCAPGRFRCV--------------CGPGYRPA--GEVCADVDECAVRPPP 790
D++EC ++ C PG F C+ C GY + G C DV+EC
Sbjct: 810 DINECTSLSEPCRPG-FSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHR 868
Query: 791 CD--QLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC-ERDTHTCQQICSNTEGSYECSC 847
C Q+CHN GSY C C+ G++ D G C DV+EC CQ C NT GSY CSC
Sbjct: 869 CGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSC 928
Query: 848 EDGY 851
G+
Sbjct: 929 ASGF 932
Score = 72.5 bits (170), Expect = 6e-12
Identities = 43/101 (42%), Positives = 52/101 (51%), Gaps = 16/101 (15%)
Query: 765 CVCGPGYR--PAGEVCADVDECAVRPPPCD--QLCHNTDGSYDCL----CRTGYELDEDG 816
C C PGY G C D++EC C + C NT GS+ C C GY L +DG
Sbjct: 702 CSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL-KDG 760
Query: 817 ANCRDVDECERDTHTCQQ--ICSNTEGSYECS----CEDGY 851
C DVDEC THTCQ +C NT+GS+ C C DG+
Sbjct: 761 -ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF 800
Score = 69.7 bits (163), Expect = 4e-11
Identities = 31/75 (41%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 845
PC Q+C GS C C GY + DG +C D++EC D HTC + C NT GS+ C
Sbjct: 688 PCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYK 747
Query: 846 --SCEDGYEKRGDAC 858
+CE GY + C
Sbjct: 748 ALTCEPGYALKDGEC 762
Score = 36.7 bits (81), Expect = 0.35
Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 821 DVDECER-DTHTCQQICSNTEGSYECSCEDGYEKRGD 856
D DEC CQ +C NT GSY C+C G+ + D
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDD 640
Score = 34.3 bits (75), Expect = 1.9
Identities = 32/119 (26%), Positives = 43/119 (36%), Gaps = 18/119 (15%)
Query: 747 DVDECAAIPG-----LC--APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHN 797
D DEC +PG LC G + C C PG+ + G C P + +
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
+ + L N C +D C+Q+CS GS CSC GY D
Sbjct: 664 ---EFSQVASNTIPLPLPQPNT-----C-KDNGPCKQVCSTVGGSAICSCFPGYAIMAD 713
>BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein.
Length = 1184
Score = 234 bits (573), Expect = 9e-61
Identities = 189/629 (30%), Positives = 253/629 (40%), Gaps = 86/629 (13%)
Query: 5 EEDQSCAGAVGVPQTKYLC-CCSVG---HAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
E++ SC G+ K C CC +G A G CE+ P G P + + GE
Sbjct: 505 EDNDSC----GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLI 560
Query: 61 VTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD-VDECSWGRPP 119
V +P + P + + G E + + L D DEC P
Sbjct: 561 VPEVRRPPEPA------AAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLL-LPG 613
Query: 120 CRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECK 179
C+N G++ C C PG+ L C ++
Sbjct: 614 ELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTI 673
Query: 180 PGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECRE 238
P + N C+D C + C + G+ +C C G+ + C D+NEC
Sbjct: 674 PLPLPQPNTCKDNGPCKQ--------VCSTVGGSAICSCFPGYAIMADGVSCEDINECVT 725
Query: 239 GGMVCRNGR-CRNTVGSFRC----ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
C G C NT+GSF C C PGY L DG C DVDEC H C C
Sbjct: 726 DLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK-DGE-CEDVDECAMGTHTC--QPGFLC 781
Query: 294 TNTNGGYECS----CGAGWKLVGR-RCVDRDECKELPYVCAGG-ECRNFNGGYVCE---- 343
NT G + C C G+ CVD +EC L C G C N G Y C+
Sbjct: 782 QNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPL 841
Query: 344 -CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERC 402
C G+ A CVD +E E G HR C EG + C
Sbjct: 842 ICARGYHASDDGAKCVD------VNECETG-VHR------------CGEG----QVCHNL 878
Query: 403 PAPDSAEFMRICQGGMGRPNLTQ---DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVL 459
P + C+ G R + D++EC P C NT GS+RC C G++L
Sbjct: 879 PGSYRCD----CKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLL 934
Query: 460 APDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRA 518
A DG C D +EC + + C C+N G Y+C C G+ D TC D+DECA+G
Sbjct: 935 AADGKRCEDVNEC--EAQRCSQ-ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAG 991
Query: 519 S-CTFRCHNTAGSFRCTCP-YGYAVAADGVHCRDIDECVQEPRVCPHA--CENVVGSYIC 574
CTFRC N GS++C CP GY + A+G C+D+DEC C A C N+ GS+ C
Sbjct: 992 ILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1051
Query: 575 ---KCPEGYRRTSAPQDSENACEDINECE 600
+CP Y + S + C D EC+
Sbjct: 1052 LRLECPPNYVQVSKTKCERTTCHDFLECQ 1080
Score = 225 bits (551), Expect = 4e-58
Identities = 163/490 (33%), Positives = 217/490 (44%), Gaps = 61/490 (12%)
Query: 151 EDVDECG--DQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGT 206
+D DEC +C H C NT+GSY C C PG++L+++ CR E P+P
Sbjct: 603 DDQDECLLLPGELCQHL-CINTVGSYHCACFPGFSLQDDGRTCRP--EGHPPQPEAPQEP 659
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLT 266
+ + N C D C++ C GS C C PGY +
Sbjct: 660 ALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQV--------CSTVGGSAICSCFPGYAIM 711
Query: 267 ADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC----SCGAGWKLVGRRCVDRDECK 322
ADG +C D++EC H C R + C NT G + C +C G+ L C D DEC
Sbjct: 712 ADGVSCEDINECVTDLHTCSRGEH--CVNTLGSFHCYKALTCEPGYALKDGECEDVDECA 769
Query: 323 ELPYVCAGGE-CRNFNGGYVCE----CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRA 377
+ C G C+N G + C+ C G+ D CVD + E
Sbjct: 770 MGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSE--------- 819
Query: 378 RPLQLARPECCCSEGAAWGRY-CERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDV 436
P RP C G Y C+R P + + G D++EC
Sbjct: 820 -P---CRPGFSCINTV--GSYTCQRNPLICARGYHASDDGAK-----CVDVNECETGVHR 868
Query: 437 CVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDP-RICGNGTCSNTRGGYECQ 494
C G+ C N GS+RC+C G+ G C+D +EC P R+C + TC NT G Y C
Sbjct: 869 CGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCS 927
Query: 495 CSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDE 553
C+ GF D + C DV+EC R C+ C N GS++C C GY +A DG C DIDE
Sbjct: 928 CASGFLLAADGKRCEDVNECEAQR--CSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDE 985
Query: 554 CVQEPRV-CPHACENVVGSYICKCPE-GYRRTSAPQDSENACEDINECEEQEDLCS-GGV 610
C Q + C C NV GSY C CPE GY T+ + +C+D++EC CS
Sbjct: 986 CAQGAGILCTFRCLNVPGSYQCACPEQGYTMTA----NGRSCKDVDECALGTHNCSEAET 1041
Query: 611 CINTDGSFLC 620
C N GSF C
Sbjct: 1042 CHNIQGSFRC 1051
Score = 217 bits (531), Expect = 1e-55
Identities = 168/529 (31%), Positives = 229/529 (43%), Gaps = 80/529 (15%)
Query: 69 DECDIMP-QLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
DEC ++P +LC+ C +T + C C G+ + CR G PP Q
Sbjct: 606 DECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPE-----GHPPQPEAPQEP 659
Query: 128 NLPGAFECRCPPGYRL-TPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
L F L P + C+D C +++C GS C C PGY +
Sbjct: 660 ALKSEFSQVASNTIPLPLPQPNTCKDNGPC--KQVCS-----TVGGSAICSCFPGYAIMA 712
Query: 187 N--VCRDVDECSRPRPVCRNGT-CENLPGAYLCH----CDDGFKAGPNNDCVDVNECREG 239
+ C D++EC C G C N G++ C+ C+ G+ A + +C DV+EC G
Sbjct: 713 DGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY-ALKDGECEDVDECAMG 771
Query: 240 GMVCRNG-RCRNTVGSFRCE----CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCT 294
C+ G C+NT GSF C+ C G+ +G NC D++EC L PC R G SC
Sbjct: 772 THTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPC-RPGF-SCI 828
Query: 295 NTNGGYECS-----CGAGWKLV--GRRCVDRDECKELPYVCAGGE-CRNFNGGYVCECPA 346
NT G Y C C G+ G +CVD +EC+ + C G+ C N G Y C+C A
Sbjct: 829 NTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKA 888
Query: 347 GWRFDKTAAVCVDERKELCYDEWEAGR-CHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
G++ D C+D + C+ GR C L C C+ G +RC
Sbjct: 889 GFQRDAFGRGCIDVNE--CWA--SPGRLCQHTCENTLGSYRCSCASGFLLAADGKRC--- 941
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
+D++EC + C C N GS++C C GY LA DG +
Sbjct: 942 -------------------EDVNECEAQR--C-SQECANIYGSYQCYCRQGYQLAEDGHT 979
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQC-SPGFTQGPD-QTCVDVDECAEGRASCT-- 521
C D DECA I C N G Y+C C G+T + ++C DVDECA G +C+
Sbjct: 980 CTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEA 1039
Query: 522 FRCHNTAGSFRC---TCPYGYA----VAADGVHCRDIDECVQEPRVCPH 563
CHN GSFRC CP Y + C D EC P H
Sbjct: 1040 ETCHNIQGSFRCLRLECPPNYVQVSKTKCERTTCHDFLECQNSPARITH 1088
Score = 177 bits (431), Expect = 1e-43
Identities = 140/469 (29%), Positives = 203/469 (43%), Gaps = 69/469 (14%)
Query: 191 DVDECSR-PRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCR 249
D DEC P +C++ C N G+Y C C GF D CR G + +
Sbjct: 604 DQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQD-----DGRTCRPEGHPPQPEAPQ 657
Query: 250 NTVGSFRCECAPGYTLTA---DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
T+ C+D C ++ C+ G CSC
Sbjct: 658 EPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQV-----------CSTVGGSAICSCFP 706
Query: 307 GWKLV--GRRCVDRDECKELPYVCAGGE-CRNFNGGYVC----ECPAGWRFDKTAAVCVD 359
G+ ++ G C D +EC + C+ GE C N G + C C G+ VD
Sbjct: 707 GYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVD 766
Query: 360 ERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMG 419
E C A H +P L C ++G+ + + +RC D F++ +G
Sbjct: 767 E----C-----AMGTHTCQPGFL----CQNTKGSFYCQARQRCM--DG--FLQDPEGNC- 808
Query: 420 RPNLTQDLDECRVRPDVCVGG-RCVNTDGSFRCE-----CPDGYVLAPDGLSCVDADECA 473
D++EC + C G C+NT GS+ C+ C GY + DG CVD +EC
Sbjct: 809 -----VDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECE 863
Query: 474 LDPRICGNG-TCSNTRGGYECQCSPGFTQGP-DQTCVDVDEC--AEGRASCTFRCHNTAG 529
CG G C N G Y C C GF + + C+DV+EC + GR C C NT G
Sbjct: 864 TGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRL-CQHTCENTLG 922
Query: 530 SFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDS 589
S+RC+C G+ +AADG C D++EC E + C C N+ GSY C C +GY+ +
Sbjct: 923 SYRCSCASGFLLAADGKRCEDVNEC--EAQRCSQECANIYGSYQCYCRQGYQLA----ED 976
Query: 590 ENACEDINECEEQEDLCSGGVCINTDGSFLCDC-DAGFEPSEDGTDCID 637
+ C DI+EC + + C+N GS+ C C + G+ + +G C D
Sbjct: 977 GHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKD 1025
Score = 138 bits (335), Expect = 6e-32
Identities = 176/660 (26%), Positives = 232/660 (35%), Gaps = 117/660 (17%)
Query: 259 CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC--V 316
CA G D C ++ E + C C + C G G C
Sbjct: 446 CAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETCGAE 505
Query: 317 DRDECKELPYV----CAGGECRNFNGGYVCECPA--GWRFDKTAAVCVDERKELCYDEWE 370
D D C Y C G R G CE G+ + C + + L E
Sbjct: 506 DNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEVR 565
Query: 371 AGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDEC 430
A P +++ E E + G E P+S P D DEC
Sbjct: 566 RPPEPAAAPRRVSEAEMAGREALSLGTEAE---LPNSL------------PG--DDQDEC 608
Query: 431 RVRPDVCVGGRCVNTDGSFRCEC-------PDGYVLAPDG----------------LSCV 467
+ P C+NT GS+ C C DG P+G S V
Sbjct: 609 LLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQV 668
Query: 468 DADECAL---DPRIC-GNG----TCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRA 518
++ L P C NG CS G C C PG+ D +C D++EC
Sbjct: 669 ASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLH 728
Query: 519 SCTF--RCHNTAGSFRC----TCPYGYAVAADGVHCRDIDECVQEPRVCPHA--CENVVG 570
+C+ C NT GSF C TC GYA+ DG C D+DEC C C+N G
Sbjct: 729 TCSRGEHCVNTLGSFHCYKALTCEPGYALK-DG-ECEDVDECAMGTHTCQPGFLCQNTKG 786
Query: 571 SYIC----KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLCD---- 621
S+ C +C +G+ QD E C DINEC + C G CINT GS+ C
Sbjct: 787 SFYCQARQRCMDGFL-----QDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPL 841
Query: 622 -CDAGFEPSEDGTDCID--------RRTG---TCYRSLVSGRCEPEXXXXXXXXXXXXXX 669
C G+ S+DG C+D R G C+ S RC+ +
Sbjct: 842 ICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCID 901
Query: 670 XXXXXXXXGHVTKAQCCCTLGAAWGSECE---LCPAPGSPAR-LDLCTAVNLTPXXXXXX 725
G + + C TLG+ + C L A G ++ C A +
Sbjct: 902 VNECWASPGRLCQHTCENTLGS-YRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIY 960
Query: 726 XXXXXXXXXXXXXXXXLDVFADVDECAAIPG-LCA------PGRFRCVCGP-GYRPA--G 775
D+DECA G LC PG ++C C GY G
Sbjct: 961 GSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG 1020
Query: 776 EVCADVDECAVRPPPCDQL--CHNTDGSYDCL---CRTGY----ELDEDGANCRDVDECE 826
C DVDECA+ C + CHN GS+ CL C Y + + C D EC+
Sbjct: 1021 RSCKDVDECALGTHNCSEAETCHNIQGSFRCLRLECPPNYVQVSKTKCERTTCHDFLECQ 1080
Score = 97.1 bits (231), Expect = 2e-19
Identities = 53/116 (45%), Positives = 64/116 (55%), Gaps = 13/116 (11%)
Query: 747 DVDECAAIPG-LCAP------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
DV+EC A PG LC G +RC C G+ A G+ C DV+EC + C Q C N
Sbjct: 901 DVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQECAN 958
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTH-TCQQICSNTEGSYECSC-EDGY 851
GSY C CR GY+L EDG C D+DEC + C C N GSY+C+C E GY
Sbjct: 959 IYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGY 1014
Score = 94.3 bits (224), Expect = 2e-18
Identities = 46/100 (46%), Positives = 55/100 (55%), Gaps = 5/100 (5%)
Query: 760 PGRFRCVCGPGY-RPA-GEVCADVDECAVRPPP-CDQLCHNTDGSYDCLCRTGYELDEDG 816
PG +RC C G+ R A G C DV+EC P C C NT GSY C C +G+ L DG
Sbjct: 879 PGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADG 938
Query: 817 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C DV+ECE C Q C+N GSY+C C GY+ D
Sbjct: 939 KRCEDVNECE--AQRCSQECANIYGSYQCYCRQGYQLAED 976
Score = 87.0 bits (206), Expect = 3e-16
Identities = 53/138 (38%), Positives = 65/138 (47%), Gaps = 26/138 (18%)
Query: 747 DVDECAAIPGLCAPG--------------RFRCVCGPGYRPAGEVCADVDECAVRPPPCD 792
DVDECA C PG R RC+ G P G C D++EC PC
Sbjct: 764 DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCR 822
Query: 793 Q--LCHNTDGSYDC-----LCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSY 843
C NT GSY C +C GY +DGA C DV+ECE H C Q+C N GSY
Sbjct: 823 PGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSY 882
Query: 844 ECSCEDGYEKR--GDACV 859
C C+ G+++ G C+
Sbjct: 883 RCDCKAGFQRDAFGRGCI 900
Score = 87.0 bits (206), Expect = 3e-16
Identities = 47/124 (37%), Positives = 60/124 (48%), Gaps = 20/124 (16%)
Query: 747 DVDECAAIPGLCAPGRFRCV--------------CGPGYRPA--GEVCADVDECAVRPPP 790
D++EC ++ C PG F C+ C GY + G C DV+EC
Sbjct: 810 DINECTSLSEPCRPG-FSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHR 868
Query: 791 CD--QLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC-ERDTHTCQQICSNTEGSYECSC 847
C Q+CHN GSY C C+ G++ D G C DV+EC CQ C NT GSY CSC
Sbjct: 869 CGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSC 928
Query: 848 EDGY 851
G+
Sbjct: 929 ASGF 932
Score = 72.5 bits (170), Expect = 6e-12
Identities = 43/101 (42%), Positives = 52/101 (51%), Gaps = 16/101 (15%)
Query: 765 CVCGPGYR--PAGEVCADVDECAVRPPPCD--QLCHNTDGSYDCL----CRTGYELDEDG 816
C C PGY G C D++EC C + C NT GS+ C C GY L +DG
Sbjct: 702 CSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL-KDG 760
Query: 817 ANCRDVDECERDTHTCQQ--ICSNTEGSYECS----CEDGY 851
C DVDEC THTCQ +C NT+GS+ C C DG+
Sbjct: 761 -ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF 800
Score = 69.7 bits (163), Expect = 4e-11
Identities = 31/75 (41%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 845
PC Q+C GS C C GY + DG +C D++EC D HTC + C NT GS+ C
Sbjct: 688 PCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYK 747
Query: 846 --SCEDGYEKRGDAC 858
+CE GY + C
Sbjct: 748 ALTCEPGYALKDGEC 762
Score = 36.7 bits (81), Expect = 0.35
Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 821 DVDECER-DTHTCQQICSNTEGSYECSCEDGYEKRGD 856
D DEC CQ +C NT GSY C+C G+ + D
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDD 640
Score = 34.3 bits (75), Expect = 1.9
Identities = 32/119 (26%), Positives = 43/119 (36%), Gaps = 18/119 (15%)
Query: 747 DVDECAAIPG-----LC--APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHN 797
D DEC +PG LC G + C C PG+ + G C P + +
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
+ + L N C +D C+Q+CS GS CSC GY D
Sbjct: 664 ---EFSQVASNTIPLPLPQPNT-----C-KDNGPCKQVCSTVGGSAICSCFPGYAIMAD 713
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1. ).
Length = 5635
Score = 228 bits (558), Expect = 6e-59
Identities = 146/433 (33%), Positives = 196/433 (45%), Gaps = 36/433 (8%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C G+ D+ C D DEC+ G P C C N G + C CP G + C+D+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNP-CSH--SCHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 154 DECG-DQRICDHG-DCRNTIGSYRCECKPGYTLRENV----CRDVDECSRPRPVCRNGTC 207
DEC + C G DC NTIGSYRC + G R C+D++EC P C C
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RC 5206
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRC-ECAPGYTL 265
N G++ C C+ G++ C+DVNECR+ VCR + C+NT G ++C + P
Sbjct: 5207 FNAIGSFHCGCEPGYQL-KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNGMT 5263
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKE 323
A+ C D+DEC + H C N C NT G Y C C G++ VGR C+D +EC++
Sbjct: 5264 KAENGTCIDIDECKDGTHQCRY--NQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 5321
Query: 324 LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKE---LCYDEWEAGRCHRAR- 378
+P CA +C N G + C CP G C ER Y + R R
Sbjct: 5322 VPKPCA-HQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 5380
Query: 379 ---PLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC-QGGMGRPNLTQDLDECRVRP 434
P Q R + R + + C +G + D+DEC
Sbjct: 5381 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECE-NT 5439
Query: 435 DVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
D C C NT GS++C CP GY L +G +C D DEC CG N C N RG Y+C
Sbjct: 5440 DAC-QHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5498
Query: 494 ---QCSPGFTQGP 503
C P + + P
Sbjct: 5499 IDTPCPPNYQRDP 5511
Score = 208 bits (508), Expect = 6e-53
Identities = 156/457 (34%), Positives = 206/457 (45%), Gaps = 62/457 (13%)
Query: 177 ECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK-AGPNNDCVDV 233
+C G+TL C D DEC+ P C + +C N G Y C C G A C D+
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNP-CSH-SCHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 234 NECREGGMVCRNGR-CRNTVGSFRC--ECAPGYTLTADGRNCRDVDECDELPHPCGRDGN 290
+EC G C G+ C NT+GS+RC C G+ T+DG +C+D++EC E PC +
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSPC----H 5203
Query: 291 PSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVC--ECPAG 347
C N G + C C G++L GR+C+D +EC++ VC + C+N GGY C CP G
Sbjct: 5204 QRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNG 5261
Query: 348 WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS 407
+ C+D DE + G H+ R Q+ C G Y RC P
Sbjct: 5262 MTKAEN-GTCID------IDECKDG-THQCRYNQI------CEN--TRGSY--RCVCPRG 5303
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
G+GRP D++EC P C +C NT GSF+C CP G L DG SC
Sbjct: 5304 YR-----SQGVGRP--CMDINECEQVPKPC-AHQCSNTPGSFKCICPPGQHLLGDGKSCA 5355
Query: 468 DADEC---ALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
+ S R Y+ Q Q Q +E R S T
Sbjct: 5356 GLERLPNYGTQYSSYNLARFSPVRNNYQPQ------QHYRQYSHLYSSYSEYRNSRT-SL 5408
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
T + R TCP G + D C DIDEC + C H C+N GSY C CP GY+ T
Sbjct: 5409 SRTRRTIRKTCPEGSEASHD--TCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLT- 5464
Query: 585 APQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
+ C+DI+EC EQ C +C N GS+ C
Sbjct: 5465 ---HNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5498
Score = 197 bits (480), Expect = 2e-49
Identities = 133/425 (31%), Positives = 187/425 (44%), Gaps = 43/425 (10%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC--RCPP 139
+CH+ + C C G C+D+DEC+ GR C C N G++ C RC
Sbjct: 5120 SCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGS 5179
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPR 199
G+R T C+D++EC + C H C N IGS+ C C+PGY L+ C DV+EC +
Sbjct: 5180 GFRRTSDGLSCQDINECQESSPC-HQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQN- 5237
Query: 200 PVCR-NGTCENLPGAYLCH--CDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSF 255
VCR + C+N G Y C C +G N C+D++EC++G CR N C NT GS+
Sbjct: 5238 -VCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSY 5296
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
RC C GY GR C D++EC+++P PC C+NT G ++C C G L+G
Sbjct: 5297 RCVCPRGYRSQGVGRPCMDINECEQVPKPCAH----QCSNTPGSFKCICPPGQHLLG--- 5349
Query: 316 VDRDECKELPYV-CAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC 374
D C L + G + ++N P + Y E+ R
Sbjct: 5350 -DGKSCAGLERLPNYGTQYSSYN--LARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRT 5406
Query: 375 HRARPLQLARPECCCSEGAAWGRY--CERCPAPDSAE---------FMRICQGG---MGR 420
+R + R C A+ + C D+ + + IC G
Sbjct: 5407 SLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHN 5466
Query: 421 PNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC---ECPDGYVLAP-DGL---SCVDAD-E 471
QD+DEC + C R C N GS++C CP Y P G +C D E
Sbjct: 5467 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLE 5526
Query: 472 CALDP 476
CAL P
Sbjct: 5527 CALSP 5531
Score = 166 bits (403), Expect = 3e-40
Identities = 91/234 (38%), Positives = 118/234 (50%), Gaps = 19/234 (8%)
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVD 193
+CP G+ L C D DEC C H C N +G+Y C C G T+ + C+D+D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 194 ECSRPRPVCRNGT-CENLPGAYLC--HCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCR 249
EC+ R C G C+N G+Y C C GF+ + C D+NEC+E C RC
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCF 5207
Query: 250 NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS--CGAG 307
N +GSF C C PGY L GR C DV+EC + + C D + C NT GGY+C C G
Sbjct: 5208 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQ--NVCRPDQH--CKNTRGGYKCIDLCPNG 5261
Query: 308 W-KLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVD 359
K C+D DECK+ + C + C N G Y C CP G+R C+D
Sbjct: 5262 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMD 5315
Score = 156 bits (378), Expect = 4e-37
Identities = 115/323 (35%), Positives = 142/323 (43%), Gaps = 47/323 (14%)
Query: 343 ECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERC 402
+CP+G+ D C DE DE AG C S A G Y C
Sbjct: 5091 QCPSGFTLDSVGPFCADE------DECAAGN------------PCSHSCHNAMGTYYCSC 5132
Query: 403 PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC--ECPDGYVL 459
P + + I G QD+DEC + C G+ C NT GS+RC C G+
Sbjct: 5133 P-----KGLTIAADG----RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRR 5183
Query: 460 APDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS 519
DGLSC D +EC + C + C N G + C C PG+ Q + C+DV+EC +
Sbjct: 5184 TSDGLSCQDINECQ-ESSPC-HQRCFNAIGSFHCGCEPGY-QLKGRKCMDVNECRQNVCR 5240
Query: 520 CTFRCHNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPH--ACENVVGSYICK 575
C NT G ++C CP G A +G C DIDEC C + CEN GSY C
Sbjct: 5241 PDQHCKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCV 5299
Query: 576 CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
CP GYR Q C DINECE+ C+ C NT GSF C C G DG C
Sbjct: 5300 CPRGYRS----QGVGRPCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDGKSC 5354
Query: 636 --IDR--RTGTCYRSLVSGRCEP 654
++R GT Y S R P
Sbjct: 5355 AGLERLPNYGTQYSSYNLARFSP 5377
Score = 151 bits (365), Expect = 1e-35
Identities = 90/255 (35%), Positives = 124/255 (48%), Gaps = 20/255 (7%)
Query: 35 CEACPPRGSPAHTAL----CGEKPGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTG 89
C A P H A+ C G I + IDEC + C G C +T
Sbjct: 5111 CAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGS 5170
Query: 90 FQC--GCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
++C C G+ + C+D++EC P C +C N G+F C C PGY+L
Sbjct: 5171 YRCVVRCGSGFRRTSDGLSCQDINECQESSP-CH--QRCFNAIGSFHCGCEPGYQLKGR- 5226
Query: 148 DECEDVDECGDQRICDHGD-CRNTIGSYRCE--CKPGYTLREN-VCRDVDECSRPRPVCR 203
+C DV+EC Q +C C+NT G Y+C C G T EN C D+DEC CR
Sbjct: 5227 -KCMDVNECR-QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCR 5284
Query: 204 -NGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAP 261
N CEN G+Y C C G+++ G C+D+NEC + C + +C NT GSF+C C P
Sbjct: 5285 YNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPP 5343
Query: 262 GYTLTADGRNCRDVD 276
G L DG++C ++
Sbjct: 5344 GQHLLGDGKSCAGLE 5358
Score = 136 bits (328), Expect = 4e-31
Identities = 119/405 (29%), Positives = 164/405 (40%), Gaps = 48/405 (11%)
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRC 315
+C G+TL + G C D DEC +PC SC N G Y CSC G + GR C
Sbjct: 5091 QCPSGFTLDSVGPFCADEDEC-AAGNPCSH----SCHNAMGTYYCSCPKGLTIAADGRTC 5145
Query: 316 VDRDECKELPYVC-AGGECRNFNGGYVC--ECPAGWRFDKTAAVCVDERKELCYDEWEAG 372
D DEC + C AG +C N G Y C C +G+R C D + C E+
Sbjct: 5146 QDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINE--CQ---ESS 5200
Query: 373 RCHRARPLQLARPECCCSEGAAW-GRYC-------ERCPAPDSA--------EFMRICQG 416
CH+ + C C G GR C + PD + + +C
Sbjct: 5201 PCHQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPN 5260
Query: 417 GMGRPN--LTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
GM + D+DEC+ C + C NT GS+RC CP GY G C+D +EC
Sbjct: 5261 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECE 5320
Query: 474 LDPRICGNGTCSNTRGGYECQCSPG-FTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
P+ C + CSNT G ++C C PG G ++C ++ + +N A
Sbjct: 5321 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPN--YGTQYSSYNLARF-- 5375
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
Y + E R + + CPEG + S +
Sbjct: 5376 SPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEG------SEASHDT 5429
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+ECE D C C NT GS+ C C G++ + +G C D
Sbjct: 5430 CVDIDECENT-DACQHE-CKNTFGSYQCICPPGYQLTHNGKTCQD 5472
Score = 122 bits (295), Expect = 4e-27
Identities = 70/179 (39%), Positives = 94/179 (52%), Gaps = 16/179 (8%)
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTFR 523
S V++D ++ + S ++G QC GFT C D DECA G C+
Sbjct: 5062 SSVESDYNQIEETLGFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECAAGNP-CSHS 5120
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA---CENVVGSYIC--KCPE 578
CHN G++ C+CP G +AADG C+DIDEC C HA C+N +GSY C +C
Sbjct: 5121 CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTC-HAGQDCDNTIGSYRCVVRCGS 5179
Query: 579 GYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
G+RRTS +C+DINEC+E C C N GSF C C+ G++ G C+D
Sbjct: 5180 GFRRTS----DGLSCQDINECQESSP-CHQR-CFNAIGSFHCGCEPGYQLK--GRKCMD 5230
Score = 97.5 bits (232), Expect = 2e-19
Identities = 48/101 (47%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Query: 759 APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDC--LCRTGYELDEDG 816
A G F C C PGY+ G C DV+EC DQ C NT G Y C LC G E+G
Sbjct: 5209 AIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 5268
Query: 817 ANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRG 855
C D+DEC+ TH C+ QIC NT GSY C C GY +G
Sbjct: 5269 -TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQG 5308
Score = 94.7 bits (225), Expect = 1e-18
Identities = 51/125 (40%), Positives = 68/125 (54%), Gaps = 12/125 (9%)
Query: 746 ADVDECAA---IPGLC--APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCD--QLCH 796
AD DECAA C A G + C C G A G C D+DECA+ C Q C
Sbjct: 5106 ADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCD 5165
Query: 797 NTDGSYDCL--CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
NT GSY C+ C +G+ DG +C+D++EC+ ++ C Q C N GS+ C CE GY+ +
Sbjct: 5166 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 5224
Query: 855 GDACV 859
G C+
Sbjct: 5225 GRKCM 5229
Score = 85.4 bits (202), Expect = 8e-16
Identities = 41/97 (42%), Positives = 48/97 (49%), Gaps = 5/97 (5%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
+C G G CAD DECA P C CHN G+Y C C G + DG C+D+D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 824 ECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD 856
EC HTC Q C NT GSY C C G+ + D
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSD 5186
Score = 85.0 bits (201), Expect = 1e-15
Identities = 48/129 (37%), Positives = 63/129 (48%), Gaps = 17/129 (13%)
Query: 747 DVDECAAIPGLCAP--------GRFRCV--CGPGYRPAGE-VCADVDECAVRPPPC--DQ 793
DV+EC +C P G ++C+ C G A C D+DEC C +Q
Sbjct: 5230 DVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQ 5287
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
+C NT GSY C+C GY G C D++ECE+ C CSNT GS++C C G
Sbjct: 5288 ICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHL 5347
Query: 854 RGD--ACVG 860
GD +C G
Sbjct: 5348 LGDGKSCAG 5356
Score = 83.0 bits (196), Expect = 4e-15
Identities = 43/103 (41%), Positives = 58/103 (56%), Gaps = 7/103 (6%)
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
S TR C G ++ TCVD+DEC E +C C NT GS++C CP GY + +
Sbjct: 5409 SRTRRTIRKTCPEG-SEASHDTCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLTHN 5466
Query: 545 GVHCRDIDECVQEPRVC-PH-ACENVVGSYIC---KCPEGYRR 582
G C+DIDEC+++ C P+ C N+ GSY C CP Y+R
Sbjct: 5467 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 5509
Score = 79.4 bits (187), Expect = 5e-14
Identities = 36/95 (37%), Positives = 51/95 (53%), Gaps = 6/95 (6%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
R C G + + C D+DEC C C NT GSY C+C GY+L +G C+D+D
Sbjct: 5416 RKTCPEGSEASHDTCVDIDECE-NTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDID 5474
Query: 824 EC-ERDTHT-CQQICSNTEGSYEC---SCEDGYEK 853
EC E++ H ++C N GSY+C C Y++
Sbjct: 5475 ECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 5509
Score = 66.5 bits (155), Expect = 4e-10
Identities = 28/65 (43%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 761 GRFRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
G +RCVC GYR G C D++EC P PC C NT GS+ C+C G L DG +
Sbjct: 5294 GSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKS 5353
Query: 819 CRDVD 823
C ++
Sbjct: 5354 CAGLE 5358
Score = 55.6 bits (128), Expect = 7e-07
Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC+ C+ C +T +QC C GY+ + C+D+DEC C C
Sbjct: 5433 IDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCF 5490
Query: 128 NLPGAFEC---RCPPGYRLTPSLDEC 150
N+ G+++C CPP Y+ P C
Sbjct: 5491 NMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Score = 52.8 bits (121), Expect = 5e-06
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 12/89 (13%)
Query: 743 DVFADVDECA---AIPGLCAP--GRFRCVCGPGYRPA--GEVCADVDECAVRPPPC--DQ 793
D D+DEC A C G ++C+C PGY+ G+ C D+DEC + C ++
Sbjct: 5428 DTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNR 5487
Query: 794 LCHNTDGSYDCL---CRTGYELDEDGANC 819
+C N GSY C+ C Y+ D C
Sbjct: 5488 MCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1. ).
Length = 5635
Score = 228 bits (558), Expect = 6e-59
Identities = 146/433 (33%), Positives = 196/433 (45%), Gaps = 36/433 (8%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C G+ D+ C D DEC+ G P C C N G + C CP G + C+D+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNP-CSH--SCHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 154 DECG-DQRICDHG-DCRNTIGSYRCECKPGYTLRENV----CRDVDECSRPRPVCRNGTC 207
DEC + C G DC NTIGSYRC + G R C+D++EC P C C
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RC 5206
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRC-ECAPGYTL 265
N G++ C C+ G++ C+DVNECR+ VCR + C+NT G ++C + P
Sbjct: 5207 FNAIGSFHCGCEPGYQL-KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNGMT 5263
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKE 323
A+ C D+DEC + H C N C NT G Y C C G++ VGR C+D +EC++
Sbjct: 5264 KAENGTCIDIDECKDGTHQCRY--NQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 5321
Query: 324 LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKE---LCYDEWEAGRCHRAR- 378
+P CA +C N G + C CP G C ER Y + R R
Sbjct: 5322 VPKPCA-HQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 5380
Query: 379 ---PLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC-QGGMGRPNLTQDLDECRVRP 434
P Q R + R + + C +G + D+DEC
Sbjct: 5381 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECE-NT 5439
Query: 435 DVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
D C C NT GS++C CP GY L +G +C D DEC CG N C N RG Y+C
Sbjct: 5440 DAC-QHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5498
Query: 494 ---QCSPGFTQGP 503
C P + + P
Sbjct: 5499 IDTPCPPNYQRDP 5511
Score = 208 bits (508), Expect = 6e-53
Identities = 156/457 (34%), Positives = 206/457 (45%), Gaps = 62/457 (13%)
Query: 177 ECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK-AGPNNDCVDV 233
+C G+TL C D DEC+ P C + +C N G Y C C G A C D+
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNP-CSH-SCHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 234 NECREGGMVCRNGR-CRNTVGSFRC--ECAPGYTLTADGRNCRDVDECDELPHPCGRDGN 290
+EC G C G+ C NT+GS+RC C G+ T+DG +C+D++EC E PC +
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSPC----H 5203
Query: 291 PSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVC--ECPAG 347
C N G + C C G++L GR+C+D +EC++ VC + C+N GGY C CP G
Sbjct: 5204 QRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNG 5261
Query: 348 WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS 407
+ C+D DE + G H+ R Q+ C G Y RC P
Sbjct: 5262 MTKAEN-GTCID------IDECKDG-THQCRYNQI------CEN--TRGSY--RCVCPRG 5303
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
G+GRP D++EC P C +C NT GSF+C CP G L DG SC
Sbjct: 5304 YR-----SQGVGRP--CMDINECEQVPKPC-AHQCSNTPGSFKCICPPGQHLLGDGKSCA 5355
Query: 468 DADEC---ALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
+ S R Y+ Q Q Q +E R S T
Sbjct: 5356 GLERLPNYGTQYSSYNLARFSPVRNNYQPQ------QHYRQYSHLYSSYSEYRNSRT-SL 5408
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
T + R TCP G + D C DIDEC + C H C+N GSY C CP GY+ T
Sbjct: 5409 SRTRRTIRKTCPEGSEASHD--TCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLT- 5464
Query: 585 APQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
+ C+DI+EC EQ C +C N GS+ C
Sbjct: 5465 ---HNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5498
Score = 197 bits (480), Expect = 2e-49
Identities = 133/425 (31%), Positives = 187/425 (44%), Gaps = 43/425 (10%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC--RCPP 139
+CH+ + C C G C+D+DEC+ GR C C N G++ C RC
Sbjct: 5120 SCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGS 5179
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPR 199
G+R T C+D++EC + C H C N IGS+ C C+PGY L+ C DV+EC +
Sbjct: 5180 GFRRTSDGLSCQDINECQESSPC-HQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQN- 5237
Query: 200 PVCR-NGTCENLPGAYLCH--CDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSF 255
VCR + C+N G Y C C +G N C+D++EC++G CR N C NT GS+
Sbjct: 5238 -VCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSY 5296
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
RC C GY GR C D++EC+++P PC C+NT G ++C C G L+G
Sbjct: 5297 RCVCPRGYRSQGVGRPCMDINECEQVPKPCAH----QCSNTPGSFKCICPPGQHLLG--- 5349
Query: 316 VDRDECKELPYV-CAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC 374
D C L + G + ++N P + Y E+ R
Sbjct: 5350 -DGKSCAGLERLPNYGTQYSSYN--LARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRT 5406
Query: 375 HRARPLQLARPECCCSEGAAWGRY--CERCPAPDSAE---------FMRICQGG---MGR 420
+R + R C A+ + C D+ + + IC G
Sbjct: 5407 SLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHN 5466
Query: 421 PNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC---ECPDGYVLAP-DGL---SCVDAD-E 471
QD+DEC + C R C N GS++C CP Y P G +C D E
Sbjct: 5467 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLE 5526
Query: 472 CALDP 476
CAL P
Sbjct: 5527 CALSP 5531
Score = 166 bits (403), Expect = 3e-40
Identities = 91/234 (38%), Positives = 118/234 (50%), Gaps = 19/234 (8%)
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVD 193
+CP G+ L C D DEC C H C N +G+Y C C G T+ + C+D+D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 194 ECSRPRPVCRNGT-CENLPGAYLC--HCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCR 249
EC+ R C G C+N G+Y C C GF+ + C D+NEC+E C RC
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCF 5207
Query: 250 NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS--CGAG 307
N +GSF C C PGY L GR C DV+EC + + C D + C NT GGY+C C G
Sbjct: 5208 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQ--NVCRPDQH--CKNTRGGYKCIDLCPNG 5261
Query: 308 W-KLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVD 359
K C+D DECK+ + C + C N G Y C CP G+R C+D
Sbjct: 5262 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMD 5315
Score = 156 bits (378), Expect = 4e-37
Identities = 115/323 (35%), Positives = 142/323 (43%), Gaps = 47/323 (14%)
Query: 343 ECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERC 402
+CP+G+ D C DE DE AG C S A G Y C
Sbjct: 5091 QCPSGFTLDSVGPFCADE------DECAAGN------------PCSHSCHNAMGTYYCSC 5132
Query: 403 PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC--ECPDGYVL 459
P + + I G QD+DEC + C G+ C NT GS+RC C G+
Sbjct: 5133 P-----KGLTIAADG----RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRR 5183
Query: 460 APDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS 519
DGLSC D +EC + C + C N G + C C PG+ Q + C+DV+EC +
Sbjct: 5184 TSDGLSCQDINECQ-ESSPC-HQRCFNAIGSFHCGCEPGY-QLKGRKCMDVNECRQNVCR 5240
Query: 520 CTFRCHNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPH--ACENVVGSYICK 575
C NT G ++C CP G A +G C DIDEC C + CEN GSY C
Sbjct: 5241 PDQHCKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCV 5299
Query: 576 CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
CP GYR Q C DINECE+ C+ C NT GSF C C G DG C
Sbjct: 5300 CPRGYRS----QGVGRPCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDGKSC 5354
Query: 636 --IDR--RTGTCYRSLVSGRCEP 654
++R GT Y S R P
Sbjct: 5355 AGLERLPNYGTQYSSYNLARFSP 5377
Score = 151 bits (365), Expect = 1e-35
Identities = 90/255 (35%), Positives = 124/255 (48%), Gaps = 20/255 (7%)
Query: 35 CEACPPRGSPAHTAL----CGEKPGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTG 89
C A P H A+ C G I + IDEC + C G C +T
Sbjct: 5111 CAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGS 5170
Query: 90 FQC--GCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
++C C G+ + C+D++EC P C +C N G+F C C PGY+L
Sbjct: 5171 YRCVVRCGSGFRRTSDGLSCQDINECQESSP-CH--QRCFNAIGSFHCGCEPGYQLKGR- 5226
Query: 148 DECEDVDECGDQRICDHGD-CRNTIGSYRCE--CKPGYTLREN-VCRDVDECSRPRPVCR 203
+C DV+EC Q +C C+NT G Y+C C G T EN C D+DEC CR
Sbjct: 5227 -KCMDVNECR-QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCR 5284
Query: 204 -NGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAP 261
N CEN G+Y C C G+++ G C+D+NEC + C + +C NT GSF+C C P
Sbjct: 5285 YNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPP 5343
Query: 262 GYTLTADGRNCRDVD 276
G L DG++C ++
Sbjct: 5344 GQHLLGDGKSCAGLE 5358
Score = 136 bits (328), Expect = 4e-31
Identities = 119/405 (29%), Positives = 164/405 (40%), Gaps = 48/405 (11%)
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRC 315
+C G+TL + G C D DEC +PC SC N G Y CSC G + GR C
Sbjct: 5091 QCPSGFTLDSVGPFCADEDEC-AAGNPCSH----SCHNAMGTYYCSCPKGLTIAADGRTC 5145
Query: 316 VDRDECKELPYVC-AGGECRNFNGGYVC--ECPAGWRFDKTAAVCVDERKELCYDEWEAG 372
D DEC + C AG +C N G Y C C +G+R C D + C E+
Sbjct: 5146 QDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINE--CQ---ESS 5200
Query: 373 RCHRARPLQLARPECCCSEGAAW-GRYC-------ERCPAPDSA--------EFMRICQG 416
CH+ + C C G GR C + PD + + +C
Sbjct: 5201 PCHQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPN 5260
Query: 417 GMGRPN--LTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
GM + D+DEC+ C + C NT GS+RC CP GY G C+D +EC
Sbjct: 5261 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECE 5320
Query: 474 LDPRICGNGTCSNTRGGYECQCSPG-FTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
P+ C + CSNT G ++C C PG G ++C ++ + +N A
Sbjct: 5321 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPN--YGTQYSSYNLARF-- 5375
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
Y + E R + + CPEG + S +
Sbjct: 5376 SPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEG------SEASHDT 5429
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+ECE D C C NT GS+ C C G++ + +G C D
Sbjct: 5430 CVDIDECENT-DACQHE-CKNTFGSYQCICPPGYQLTHNGKTCQD 5472
Score = 122 bits (295), Expect = 4e-27
Identities = 70/179 (39%), Positives = 94/179 (52%), Gaps = 16/179 (8%)
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTFR 523
S V++D ++ + S ++G QC GFT C D DECA G C+
Sbjct: 5062 SSVESDYNQIEETLGFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECAAGNP-CSHS 5120
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA---CENVVGSYIC--KCPE 578
CHN G++ C+CP G +AADG C+DIDEC C HA C+N +GSY C +C
Sbjct: 5121 CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTC-HAGQDCDNTIGSYRCVVRCGS 5179
Query: 579 GYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
G+RRTS +C+DINEC+E C C N GSF C C+ G++ G C+D
Sbjct: 5180 GFRRTS----DGLSCQDINECQESSP-CHQR-CFNAIGSFHCGCEPGYQLK--GRKCMD 5230
Score = 97.5 bits (232), Expect = 2e-19
Identities = 48/101 (47%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Query: 759 APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDC--LCRTGYELDEDG 816
A G F C C PGY+ G C DV+EC DQ C NT G Y C LC G E+G
Sbjct: 5209 AIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 5268
Query: 817 ANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRG 855
C D+DEC+ TH C+ QIC NT GSY C C GY +G
Sbjct: 5269 -TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQG 5308
Score = 94.7 bits (225), Expect = 1e-18
Identities = 51/125 (40%), Positives = 68/125 (54%), Gaps = 12/125 (9%)
Query: 746 ADVDECAA---IPGLC--APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCD--QLCH 796
AD DECAA C A G + C C G A G C D+DECA+ C Q C
Sbjct: 5106 ADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCD 5165
Query: 797 NTDGSYDCL--CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
NT GSY C+ C +G+ DG +C+D++EC+ ++ C Q C N GS+ C CE GY+ +
Sbjct: 5166 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 5224
Query: 855 GDACV 859
G C+
Sbjct: 5225 GRKCM 5229
Score = 85.4 bits (202), Expect = 8e-16
Identities = 41/97 (42%), Positives = 48/97 (49%), Gaps = 5/97 (5%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
+C G G CAD DECA P C CHN G+Y C C G + DG C+D+D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 824 ECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD 856
EC HTC Q C NT GSY C C G+ + D
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSD 5186
Score = 85.0 bits (201), Expect = 1e-15
Identities = 48/129 (37%), Positives = 63/129 (48%), Gaps = 17/129 (13%)
Query: 747 DVDECAAIPGLCAP--------GRFRCV--CGPGYRPAGE-VCADVDECAVRPPPC--DQ 793
DV+EC +C P G ++C+ C G A C D+DEC C +Q
Sbjct: 5230 DVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQ 5287
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
+C NT GSY C+C GY G C D++ECE+ C CSNT GS++C C G
Sbjct: 5288 ICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHL 5347
Query: 854 RGD--ACVG 860
GD +C G
Sbjct: 5348 LGDGKSCAG 5356
Score = 83.0 bits (196), Expect = 4e-15
Identities = 43/103 (41%), Positives = 58/103 (56%), Gaps = 7/103 (6%)
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
S TR C G ++ TCVD+DEC E +C C NT GS++C CP GY + +
Sbjct: 5409 SRTRRTIRKTCPEG-SEASHDTCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLTHN 5466
Query: 545 GVHCRDIDECVQEPRVC-PH-ACENVVGSYIC---KCPEGYRR 582
G C+DIDEC+++ C P+ C N+ GSY C CP Y+R
Sbjct: 5467 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 5509
Score = 79.4 bits (187), Expect = 5e-14
Identities = 36/95 (37%), Positives = 51/95 (53%), Gaps = 6/95 (6%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
R C G + + C D+DEC C C NT GSY C+C GY+L +G C+D+D
Sbjct: 5416 RKTCPEGSEASHDTCVDIDECE-NTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDID 5474
Query: 824 EC-ERDTHT-CQQICSNTEGSYEC---SCEDGYEK 853
EC E++ H ++C N GSY+C C Y++
Sbjct: 5475 ECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 5509
Score = 66.5 bits (155), Expect = 4e-10
Identities = 28/65 (43%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 761 GRFRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
G +RCVC GYR G C D++EC P PC C NT GS+ C+C G L DG +
Sbjct: 5294 GSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKS 5353
Query: 819 CRDVD 823
C ++
Sbjct: 5354 CAGLE 5358
Score = 55.6 bits (128), Expect = 7e-07
Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC+ C+ C +T +QC C GY+ + C+D+DEC C C
Sbjct: 5433 IDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCF 5490
Query: 128 NLPGAFEC---RCPPGYRLTPSLDEC 150
N+ G+++C CPP Y+ P C
Sbjct: 5491 NMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Score = 52.8 bits (121), Expect = 5e-06
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 12/89 (13%)
Query: 743 DVFADVDECA---AIPGLCAP--GRFRCVCGPGYRPA--GEVCADVDECAVRPPPC--DQ 793
D D+DEC A C G ++C+C PGY+ G+ C D+DEC + C ++
Sbjct: 5428 DTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNR 5487
Query: 794 LCHNTDGSYDCL---CRTGYELDEDGANC 819
+C N GSY C+ C Y+ D C
Sbjct: 5488 MCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1. ).
Length = 5635
Score = 228 bits (558), Expect = 6e-59
Identities = 146/433 (33%), Positives = 196/433 (45%), Gaps = 36/433 (8%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C G+ D+ C D DEC+ G P C C N G + C CP G + C+D+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNP-CSH--SCHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 154 DECG-DQRICDHG-DCRNTIGSYRCECKPGYTLRENV----CRDVDECSRPRPVCRNGTC 207
DEC + C G DC NTIGSYRC + G R C+D++EC P C C
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RC 5206
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRC-ECAPGYTL 265
N G++ C C+ G++ C+DVNECR+ VCR + C+NT G ++C + P
Sbjct: 5207 FNAIGSFHCGCEPGYQL-KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNGMT 5263
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKE 323
A+ C D+DEC + H C N C NT G Y C C G++ VGR C+D +EC++
Sbjct: 5264 KAENGTCIDIDECKDGTHQCRY--NQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 5321
Query: 324 LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKE---LCYDEWEAGRCHRAR- 378
+P CA +C N G + C CP G C ER Y + R R
Sbjct: 5322 VPKPCA-HQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 5380
Query: 379 ---PLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC-QGGMGRPNLTQDLDECRVRP 434
P Q R + R + + C +G + D+DEC
Sbjct: 5381 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECE-NT 5439
Query: 435 DVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
D C C NT GS++C CP GY L +G +C D DEC CG N C N RG Y+C
Sbjct: 5440 DAC-QHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5498
Query: 494 ---QCSPGFTQGP 503
C P + + P
Sbjct: 5499 IDTPCPPNYQRDP 5511
Score = 208 bits (508), Expect = 6e-53
Identities = 156/457 (34%), Positives = 206/457 (45%), Gaps = 62/457 (13%)
Query: 177 ECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK-AGPNNDCVDV 233
+C G+TL C D DEC+ P C + +C N G Y C C G A C D+
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNP-CSH-SCHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 234 NECREGGMVCRNGR-CRNTVGSFRC--ECAPGYTLTADGRNCRDVDECDELPHPCGRDGN 290
+EC G C G+ C NT+GS+RC C G+ T+DG +C+D++EC E PC +
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSPC----H 5203
Query: 291 PSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVC--ECPAG 347
C N G + C C G++L GR+C+D +EC++ VC + C+N GGY C CP G
Sbjct: 5204 QRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNG 5261
Query: 348 WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS 407
+ C+D DE + G H+ R Q+ C G Y RC P
Sbjct: 5262 MTKAEN-GTCID------IDECKDG-THQCRYNQI------CEN--TRGSY--RCVCPRG 5303
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
G+GRP D++EC P C +C NT GSF+C CP G L DG SC
Sbjct: 5304 YR-----SQGVGRP--CMDINECEQVPKPC-AHQCSNTPGSFKCICPPGQHLLGDGKSCA 5355
Query: 468 DADEC---ALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
+ S R Y+ Q Q Q +E R S T
Sbjct: 5356 GLERLPNYGTQYSSYNLARFSPVRNNYQPQ------QHYRQYSHLYSSYSEYRNSRT-SL 5408
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
T + R TCP G + D C DIDEC + C H C+N GSY C CP GY+ T
Sbjct: 5409 SRTRRTIRKTCPEGSEASHD--TCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLT- 5464
Query: 585 APQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
+ C+DI+EC EQ C +C N GS+ C
Sbjct: 5465 ---HNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5498
Score = 197 bits (480), Expect = 2e-49
Identities = 133/425 (31%), Positives = 187/425 (44%), Gaps = 43/425 (10%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC--RCPP 139
+CH+ + C C G C+D+DEC+ GR C C N G++ C RC
Sbjct: 5120 SCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGS 5179
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPR 199
G+R T C+D++EC + C H C N IGS+ C C+PGY L+ C DV+EC +
Sbjct: 5180 GFRRTSDGLSCQDINECQESSPC-HQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQN- 5237
Query: 200 PVCR-NGTCENLPGAYLCH--CDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSF 255
VCR + C+N G Y C C +G N C+D++EC++G CR N C NT GS+
Sbjct: 5238 -VCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSY 5296
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
RC C GY GR C D++EC+++P PC C+NT G ++C C G L+G
Sbjct: 5297 RCVCPRGYRSQGVGRPCMDINECEQVPKPCAH----QCSNTPGSFKCICPPGQHLLG--- 5349
Query: 316 VDRDECKELPYV-CAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC 374
D C L + G + ++N P + Y E+ R
Sbjct: 5350 -DGKSCAGLERLPNYGTQYSSYN--LARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRT 5406
Query: 375 HRARPLQLARPECCCSEGAAWGRY--CERCPAPDSAE---------FMRICQGG---MGR 420
+R + R C A+ + C D+ + + IC G
Sbjct: 5407 SLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHN 5466
Query: 421 PNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC---ECPDGYVLAP-DGL---SCVDAD-E 471
QD+DEC + C R C N GS++C CP Y P G +C D E
Sbjct: 5467 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLE 5526
Query: 472 CALDP 476
CAL P
Sbjct: 5527 CALSP 5531
Score = 166 bits (403), Expect = 3e-40
Identities = 91/234 (38%), Positives = 118/234 (50%), Gaps = 19/234 (8%)
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVD 193
+CP G+ L C D DEC C H C N +G+Y C C G T+ + C+D+D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 194 ECSRPRPVCRNGT-CENLPGAYLC--HCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCR 249
EC+ R C G C+N G+Y C C GF+ + C D+NEC+E C RC
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCF 5207
Query: 250 NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS--CGAG 307
N +GSF C C PGY L GR C DV+EC + + C D + C NT GGY+C C G
Sbjct: 5208 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQ--NVCRPDQH--CKNTRGGYKCIDLCPNG 5261
Query: 308 W-KLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVD 359
K C+D DECK+ + C + C N G Y C CP G+R C+D
Sbjct: 5262 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMD 5315
Score = 156 bits (378), Expect = 4e-37
Identities = 115/323 (35%), Positives = 142/323 (43%), Gaps = 47/323 (14%)
Query: 343 ECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERC 402
+CP+G+ D C DE DE AG C S A G Y C
Sbjct: 5091 QCPSGFTLDSVGPFCADE------DECAAGN------------PCSHSCHNAMGTYYCSC 5132
Query: 403 PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC--ECPDGYVL 459
P + + I G QD+DEC + C G+ C NT GS+RC C G+
Sbjct: 5133 P-----KGLTIAADG----RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRR 5183
Query: 460 APDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS 519
DGLSC D +EC + C + C N G + C C PG+ Q + C+DV+EC +
Sbjct: 5184 TSDGLSCQDINECQ-ESSPC-HQRCFNAIGSFHCGCEPGY-QLKGRKCMDVNECRQNVCR 5240
Query: 520 CTFRCHNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPH--ACENVVGSYICK 575
C NT G ++C CP G A +G C DIDEC C + CEN GSY C
Sbjct: 5241 PDQHCKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCV 5299
Query: 576 CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
CP GYR Q C DINECE+ C+ C NT GSF C C G DG C
Sbjct: 5300 CPRGYRS----QGVGRPCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDGKSC 5354
Query: 636 --IDR--RTGTCYRSLVSGRCEP 654
++R GT Y S R P
Sbjct: 5355 AGLERLPNYGTQYSSYNLARFSP 5377
Score = 151 bits (365), Expect = 1e-35
Identities = 90/255 (35%), Positives = 124/255 (48%), Gaps = 20/255 (7%)
Query: 35 CEACPPRGSPAHTAL----CGEKPGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTG 89
C A P H A+ C G I + IDEC + C G C +T
Sbjct: 5111 CAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGS 5170
Query: 90 FQC--GCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
++C C G+ + C+D++EC P C +C N G+F C C PGY+L
Sbjct: 5171 YRCVVRCGSGFRRTSDGLSCQDINECQESSP-CH--QRCFNAIGSFHCGCEPGYQLKGR- 5226
Query: 148 DECEDVDECGDQRICDHGD-CRNTIGSYRCE--CKPGYTLREN-VCRDVDECSRPRPVCR 203
+C DV+EC Q +C C+NT G Y+C C G T EN C D+DEC CR
Sbjct: 5227 -KCMDVNECR-QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCR 5284
Query: 204 -NGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAP 261
N CEN G+Y C C G+++ G C+D+NEC + C + +C NT GSF+C C P
Sbjct: 5285 YNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPP 5343
Query: 262 GYTLTADGRNCRDVD 276
G L DG++C ++
Sbjct: 5344 GQHLLGDGKSCAGLE 5358
Score = 136 bits (328), Expect = 4e-31
Identities = 119/405 (29%), Positives = 164/405 (40%), Gaps = 48/405 (11%)
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRC 315
+C G+TL + G C D DEC +PC SC N G Y CSC G + GR C
Sbjct: 5091 QCPSGFTLDSVGPFCADEDEC-AAGNPCSH----SCHNAMGTYYCSCPKGLTIAADGRTC 5145
Query: 316 VDRDECKELPYVC-AGGECRNFNGGYVC--ECPAGWRFDKTAAVCVDERKELCYDEWEAG 372
D DEC + C AG +C N G Y C C +G+R C D + C E+
Sbjct: 5146 QDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINE--CQ---ESS 5200
Query: 373 RCHRARPLQLARPECCCSEGAAW-GRYC-------ERCPAPDSA--------EFMRICQG 416
CH+ + C C G GR C + PD + + +C
Sbjct: 5201 PCHQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPN 5260
Query: 417 GMGRPN--LTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
GM + D+DEC+ C + C NT GS+RC CP GY G C+D +EC
Sbjct: 5261 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECE 5320
Query: 474 LDPRICGNGTCSNTRGGYECQCSPG-FTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
P+ C + CSNT G ++C C PG G ++C ++ + +N A
Sbjct: 5321 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPN--YGTQYSSYNLARF-- 5375
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
Y + E R + + CPEG + S +
Sbjct: 5376 SPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEG------SEASHDT 5429
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+ECE D C C NT GS+ C C G++ + +G C D
Sbjct: 5430 CVDIDECENT-DACQHE-CKNTFGSYQCICPPGYQLTHNGKTCQD 5472
Score = 122 bits (295), Expect = 4e-27
Identities = 70/179 (39%), Positives = 94/179 (52%), Gaps = 16/179 (8%)
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTFR 523
S V++D ++ + S ++G QC GFT C D DECA G C+
Sbjct: 5062 SSVESDYNQIEETLGFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECAAGNP-CSHS 5120
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA---CENVVGSYIC--KCPE 578
CHN G++ C+CP G +AADG C+DIDEC C HA C+N +GSY C +C
Sbjct: 5121 CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTC-HAGQDCDNTIGSYRCVVRCGS 5179
Query: 579 GYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
G+RRTS +C+DINEC+E C C N GSF C C+ G++ G C+D
Sbjct: 5180 GFRRTS----DGLSCQDINECQESSP-CHQR-CFNAIGSFHCGCEPGYQLK--GRKCMD 5230
Score = 97.5 bits (232), Expect = 2e-19
Identities = 48/101 (47%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Query: 759 APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDC--LCRTGYELDEDG 816
A G F C C PGY+ G C DV+EC DQ C NT G Y C LC G E+G
Sbjct: 5209 AIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 5268
Query: 817 ANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRG 855
C D+DEC+ TH C+ QIC NT GSY C C GY +G
Sbjct: 5269 -TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQG 5308
Score = 94.7 bits (225), Expect = 1e-18
Identities = 51/125 (40%), Positives = 68/125 (54%), Gaps = 12/125 (9%)
Query: 746 ADVDECAA---IPGLC--APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCD--QLCH 796
AD DECAA C A G + C C G A G C D+DECA+ C Q C
Sbjct: 5106 ADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCD 5165
Query: 797 NTDGSYDCL--CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
NT GSY C+ C +G+ DG +C+D++EC+ ++ C Q C N GS+ C CE GY+ +
Sbjct: 5166 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 5224
Query: 855 GDACV 859
G C+
Sbjct: 5225 GRKCM 5229
Score = 85.4 bits (202), Expect = 8e-16
Identities = 41/97 (42%), Positives = 48/97 (49%), Gaps = 5/97 (5%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
+C G G CAD DECA P C CHN G+Y C C G + DG C+D+D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 824 ECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD 856
EC HTC Q C NT GSY C C G+ + D
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSD 5186
Score = 85.0 bits (201), Expect = 1e-15
Identities = 48/129 (37%), Positives = 63/129 (48%), Gaps = 17/129 (13%)
Query: 747 DVDECAAIPGLCAP--------GRFRCV--CGPGYRPAGE-VCADVDECAVRPPPC--DQ 793
DV+EC +C P G ++C+ C G A C D+DEC C +Q
Sbjct: 5230 DVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQ 5287
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
+C NT GSY C+C GY G C D++ECE+ C CSNT GS++C C G
Sbjct: 5288 ICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHL 5347
Query: 854 RGD--ACVG 860
GD +C G
Sbjct: 5348 LGDGKSCAG 5356
Score = 83.0 bits (196), Expect = 4e-15
Identities = 43/103 (41%), Positives = 58/103 (56%), Gaps = 7/103 (6%)
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
S TR C G ++ TCVD+DEC E +C C NT GS++C CP GY + +
Sbjct: 5409 SRTRRTIRKTCPEG-SEASHDTCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLTHN 5466
Query: 545 GVHCRDIDECVQEPRVC-PH-ACENVVGSYIC---KCPEGYRR 582
G C+DIDEC+++ C P+ C N+ GSY C CP Y+R
Sbjct: 5467 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 5509
Score = 79.4 bits (187), Expect = 5e-14
Identities = 36/95 (37%), Positives = 51/95 (53%), Gaps = 6/95 (6%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
R C G + + C D+DEC C C NT GSY C+C GY+L +G C+D+D
Sbjct: 5416 RKTCPEGSEASHDTCVDIDECE-NTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDID 5474
Query: 824 EC-ERDTHT-CQQICSNTEGSYEC---SCEDGYEK 853
EC E++ H ++C N GSY+C C Y++
Sbjct: 5475 ECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 5509
Score = 66.5 bits (155), Expect = 4e-10
Identities = 28/65 (43%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 761 GRFRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
G +RCVC GYR G C D++EC P PC C NT GS+ C+C G L DG +
Sbjct: 5294 GSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKS 5353
Query: 819 CRDVD 823
C ++
Sbjct: 5354 CAGLE 5358
Score = 55.6 bits (128), Expect = 7e-07
Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC+ C+ C +T +QC C GY+ + C+D+DEC C C
Sbjct: 5433 IDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCF 5490
Query: 128 NLPGAFEC---RCPPGYRLTPSLDEC 150
N+ G+++C CPP Y+ P C
Sbjct: 5491 NMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Score = 52.8 bits (121), Expect = 5e-06
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 12/89 (13%)
Query: 743 DVFADVDECA---AIPGLCAP--GRFRCVCGPGYRPA--GEVCADVDECAVRPPPC--DQ 793
D D+DEC A C G ++C+C PGY+ G+ C D+DEC + C ++
Sbjct: 5428 DTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNR 5487
Query: 794 LCHNTDGSYDCL---CRTGYELDEDGANC 819
+C N GSY C+ C Y+ D C
Sbjct: 5488 MCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1. ).
Length = 5635
Score = 228 bits (558), Expect = 6e-59
Identities = 146/433 (33%), Positives = 196/433 (45%), Gaps = 36/433 (8%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C G+ D+ C D DEC+ G P C C N G + C CP G + C+D+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNP-CSH--SCHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 154 DECG-DQRICDHG-DCRNTIGSYRCECKPGYTLRENV----CRDVDECSRPRPVCRNGTC 207
DEC + C G DC NTIGSYRC + G R C+D++EC P C C
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RC 5206
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRC-ECAPGYTL 265
N G++ C C+ G++ C+DVNECR+ VCR + C+NT G ++C + P
Sbjct: 5207 FNAIGSFHCGCEPGYQL-KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNGMT 5263
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKE 323
A+ C D+DEC + H C N C NT G Y C C G++ VGR C+D +EC++
Sbjct: 5264 KAENGTCIDIDECKDGTHQCRY--NQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 5321
Query: 324 LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKE---LCYDEWEAGRCHRAR- 378
+P CA +C N G + C CP G C ER Y + R R
Sbjct: 5322 VPKPCA-HQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 5380
Query: 379 ---PLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC-QGGMGRPNLTQDLDECRVRP 434
P Q R + R + + C +G + D+DEC
Sbjct: 5381 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECE-NT 5439
Query: 435 DVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
D C C NT GS++C CP GY L +G +C D DEC CG N C N RG Y+C
Sbjct: 5440 DAC-QHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5498
Query: 494 ---QCSPGFTQGP 503
C P + + P
Sbjct: 5499 IDTPCPPNYQRDP 5511
Score = 208 bits (508), Expect = 6e-53
Identities = 156/457 (34%), Positives = 206/457 (45%), Gaps = 62/457 (13%)
Query: 177 ECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK-AGPNNDCVDV 233
+C G+TL C D DEC+ P C + +C N G Y C C G A C D+
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNP-CSH-SCHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 234 NECREGGMVCRNGR-CRNTVGSFRC--ECAPGYTLTADGRNCRDVDECDELPHPCGRDGN 290
+EC G C G+ C NT+GS+RC C G+ T+DG +C+D++EC E PC +
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSPC----H 5203
Query: 291 PSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVC--ECPAG 347
C N G + C C G++L GR+C+D +EC++ VC + C+N GGY C CP G
Sbjct: 5204 QRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNG 5261
Query: 348 WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS 407
+ C+D DE + G H+ R Q+ C G Y RC P
Sbjct: 5262 MTKAEN-GTCID------IDECKDG-THQCRYNQI------CEN--TRGSY--RCVCPRG 5303
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
G+GRP D++EC P C +C NT GSF+C CP G L DG SC
Sbjct: 5304 YR-----SQGVGRP--CMDINECEQVPKPC-AHQCSNTPGSFKCICPPGQHLLGDGKSCA 5355
Query: 468 DADEC---ALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
+ S R Y+ Q Q Q +E R S T
Sbjct: 5356 GLERLPNYGTQYSSYNLARFSPVRNNYQPQ------QHYRQYSHLYSSYSEYRNSRT-SL 5408
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
T + R TCP G + D C DIDEC + C H C+N GSY C CP GY+ T
Sbjct: 5409 SRTRRTIRKTCPEGSEASHD--TCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLT- 5464
Query: 585 APQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
+ C+DI+EC EQ C +C N GS+ C
Sbjct: 5465 ---HNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5498
Score = 197 bits (480), Expect = 2e-49
Identities = 133/425 (31%), Positives = 187/425 (44%), Gaps = 43/425 (10%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC--RCPP 139
+CH+ + C C G C+D+DEC+ GR C C N G++ C RC
Sbjct: 5120 SCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGS 5179
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPR 199
G+R T C+D++EC + C H C N IGS+ C C+PGY L+ C DV+EC +
Sbjct: 5180 GFRRTSDGLSCQDINECQESSPC-HQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQN- 5237
Query: 200 PVCR-NGTCENLPGAYLCH--CDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSF 255
VCR + C+N G Y C C +G N C+D++EC++G CR N C NT GS+
Sbjct: 5238 -VCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSY 5296
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
RC C GY GR C D++EC+++P PC C+NT G ++C C G L+G
Sbjct: 5297 RCVCPRGYRSQGVGRPCMDINECEQVPKPCAH----QCSNTPGSFKCICPPGQHLLG--- 5349
Query: 316 VDRDECKELPYV-CAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC 374
D C L + G + ++N P + Y E+ R
Sbjct: 5350 -DGKSCAGLERLPNYGTQYSSYN--LARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRT 5406
Query: 375 HRARPLQLARPECCCSEGAAWGRY--CERCPAPDSAE---------FMRICQGG---MGR 420
+R + R C A+ + C D+ + + IC G
Sbjct: 5407 SLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHN 5466
Query: 421 PNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC---ECPDGYVLAP-DGL---SCVDAD-E 471
QD+DEC + C R C N GS++C CP Y P G +C D E
Sbjct: 5467 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLE 5526
Query: 472 CALDP 476
CAL P
Sbjct: 5527 CALSP 5531
Score = 166 bits (403), Expect = 3e-40
Identities = 91/234 (38%), Positives = 118/234 (50%), Gaps = 19/234 (8%)
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVD 193
+CP G+ L C D DEC C H C N +G+Y C C G T+ + C+D+D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 194 ECSRPRPVCRNGT-CENLPGAYLC--HCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCR 249
EC+ R C G C+N G+Y C C GF+ + C D+NEC+E C RC
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCF 5207
Query: 250 NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS--CGAG 307
N +GSF C C PGY L GR C DV+EC + + C D + C NT GGY+C C G
Sbjct: 5208 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQ--NVCRPDQH--CKNTRGGYKCIDLCPNG 5261
Query: 308 W-KLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVD 359
K C+D DECK+ + C + C N G Y C CP G+R C+D
Sbjct: 5262 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMD 5315
Score = 156 bits (378), Expect = 4e-37
Identities = 115/323 (35%), Positives = 142/323 (43%), Gaps = 47/323 (14%)
Query: 343 ECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERC 402
+CP+G+ D C DE DE AG C S A G Y C
Sbjct: 5091 QCPSGFTLDSVGPFCADE------DECAAGN------------PCSHSCHNAMGTYYCSC 5132
Query: 403 PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC--ECPDGYVL 459
P + + I G QD+DEC + C G+ C NT GS+RC C G+
Sbjct: 5133 P-----KGLTIAADG----RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRR 5183
Query: 460 APDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS 519
DGLSC D +EC + C + C N G + C C PG+ Q + C+DV+EC +
Sbjct: 5184 TSDGLSCQDINECQ-ESSPC-HQRCFNAIGSFHCGCEPGY-QLKGRKCMDVNECRQNVCR 5240
Query: 520 CTFRCHNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPH--ACENVVGSYICK 575
C NT G ++C CP G A +G C DIDEC C + CEN GSY C
Sbjct: 5241 PDQHCKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCV 5299
Query: 576 CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
CP GYR Q C DINECE+ C+ C NT GSF C C G DG C
Sbjct: 5300 CPRGYRS----QGVGRPCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDGKSC 5354
Query: 636 --IDR--RTGTCYRSLVSGRCEP 654
++R GT Y S R P
Sbjct: 5355 AGLERLPNYGTQYSSYNLARFSP 5377
Score = 151 bits (365), Expect = 1e-35
Identities = 90/255 (35%), Positives = 124/255 (48%), Gaps = 20/255 (7%)
Query: 35 CEACPPRGSPAHTAL----CGEKPGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTG 89
C A P H A+ C G I + IDEC + C G C +T
Sbjct: 5111 CAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGS 5170
Query: 90 FQC--GCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
++C C G+ + C+D++EC P C +C N G+F C C PGY+L
Sbjct: 5171 YRCVVRCGSGFRRTSDGLSCQDINECQESSP-CH--QRCFNAIGSFHCGCEPGYQLKGR- 5226
Query: 148 DECEDVDECGDQRICDHGD-CRNTIGSYRCE--CKPGYTLREN-VCRDVDECSRPRPVCR 203
+C DV+EC Q +C C+NT G Y+C C G T EN C D+DEC CR
Sbjct: 5227 -KCMDVNECR-QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCR 5284
Query: 204 -NGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAP 261
N CEN G+Y C C G+++ G C+D+NEC + C + +C NT GSF+C C P
Sbjct: 5285 YNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPP 5343
Query: 262 GYTLTADGRNCRDVD 276
G L DG++C ++
Sbjct: 5344 GQHLLGDGKSCAGLE 5358
Score = 136 bits (328), Expect = 4e-31
Identities = 119/405 (29%), Positives = 164/405 (40%), Gaps = 48/405 (11%)
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRC 315
+C G+TL + G C D DEC +PC SC N G Y CSC G + GR C
Sbjct: 5091 QCPSGFTLDSVGPFCADEDEC-AAGNPCSH----SCHNAMGTYYCSCPKGLTIAADGRTC 5145
Query: 316 VDRDECKELPYVC-AGGECRNFNGGYVC--ECPAGWRFDKTAAVCVDERKELCYDEWEAG 372
D DEC + C AG +C N G Y C C +G+R C D + C E+
Sbjct: 5146 QDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINE--CQ---ESS 5200
Query: 373 RCHRARPLQLARPECCCSEGAAW-GRYC-------ERCPAPDSA--------EFMRICQG 416
CH+ + C C G GR C + PD + + +C
Sbjct: 5201 PCHQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPN 5260
Query: 417 GMGRPN--LTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
GM + D+DEC+ C + C NT GS+RC CP GY G C+D +EC
Sbjct: 5261 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECE 5320
Query: 474 LDPRICGNGTCSNTRGGYECQCSPG-FTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
P+ C + CSNT G ++C C PG G ++C ++ + +N A
Sbjct: 5321 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPN--YGTQYSSYNLARF-- 5375
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
Y + E R + + CPEG + S +
Sbjct: 5376 SPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEG------SEASHDT 5429
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+ECE D C C NT GS+ C C G++ + +G C D
Sbjct: 5430 CVDIDECENT-DACQHE-CKNTFGSYQCICPPGYQLTHNGKTCQD 5472
Score = 122 bits (295), Expect = 4e-27
Identities = 70/179 (39%), Positives = 94/179 (52%), Gaps = 16/179 (8%)
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTFR 523
S V++D ++ + S ++G QC GFT C D DECA G C+
Sbjct: 5062 SSVESDYNQIEETLGFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECAAGNP-CSHS 5120
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA---CENVVGSYIC--KCPE 578
CHN G++ C+CP G +AADG C+DIDEC C HA C+N +GSY C +C
Sbjct: 5121 CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTC-HAGQDCDNTIGSYRCVVRCGS 5179
Query: 579 GYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
G+RRTS +C+DINEC+E C C N GSF C C+ G++ G C+D
Sbjct: 5180 GFRRTS----DGLSCQDINECQESSP-CHQR-CFNAIGSFHCGCEPGYQLK--GRKCMD 5230
Score = 97.5 bits (232), Expect = 2e-19
Identities = 48/101 (47%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Query: 759 APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDC--LCRTGYELDEDG 816
A G F C C PGY+ G C DV+EC DQ C NT G Y C LC G E+G
Sbjct: 5209 AIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 5268
Query: 817 ANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRG 855
C D+DEC+ TH C+ QIC NT GSY C C GY +G
Sbjct: 5269 -TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQG 5308
Score = 94.7 bits (225), Expect = 1e-18
Identities = 51/125 (40%), Positives = 68/125 (54%), Gaps = 12/125 (9%)
Query: 746 ADVDECAA---IPGLC--APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCD--QLCH 796
AD DECAA C A G + C C G A G C D+DECA+ C Q C
Sbjct: 5106 ADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCD 5165
Query: 797 NTDGSYDCL--CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
NT GSY C+ C +G+ DG +C+D++EC+ ++ C Q C N GS+ C CE GY+ +
Sbjct: 5166 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 5224
Query: 855 GDACV 859
G C+
Sbjct: 5225 GRKCM 5229
Score = 85.4 bits (202), Expect = 8e-16
Identities = 41/97 (42%), Positives = 48/97 (49%), Gaps = 5/97 (5%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
+C G G CAD DECA P C CHN G+Y C C G + DG C+D+D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 824 ECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD 856
EC HTC Q C NT GSY C C G+ + D
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSD 5186
Score = 85.0 bits (201), Expect = 1e-15
Identities = 48/129 (37%), Positives = 63/129 (48%), Gaps = 17/129 (13%)
Query: 747 DVDECAAIPGLCAP--------GRFRCV--CGPGYRPAGE-VCADVDECAVRPPPC--DQ 793
DV+EC +C P G ++C+ C G A C D+DEC C +Q
Sbjct: 5230 DVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQ 5287
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
+C NT GSY C+C GY G C D++ECE+ C CSNT GS++C C G
Sbjct: 5288 ICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHL 5347
Query: 854 RGD--ACVG 860
GD +C G
Sbjct: 5348 LGDGKSCAG 5356
Score = 83.0 bits (196), Expect = 4e-15
Identities = 43/103 (41%), Positives = 58/103 (56%), Gaps = 7/103 (6%)
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
S TR C G ++ TCVD+DEC E +C C NT GS++C CP GY + +
Sbjct: 5409 SRTRRTIRKTCPEG-SEASHDTCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLTHN 5466
Query: 545 GVHCRDIDECVQEPRVC-PH-ACENVVGSYIC---KCPEGYRR 582
G C+DIDEC+++ C P+ C N+ GSY C CP Y+R
Sbjct: 5467 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 5509
Score = 79.4 bits (187), Expect = 5e-14
Identities = 36/95 (37%), Positives = 51/95 (53%), Gaps = 6/95 (6%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
R C G + + C D+DEC C C NT GSY C+C GY+L +G C+D+D
Sbjct: 5416 RKTCPEGSEASHDTCVDIDECE-NTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDID 5474
Query: 824 EC-ERDTHT-CQQICSNTEGSYEC---SCEDGYEK 853
EC E++ H ++C N GSY+C C Y++
Sbjct: 5475 ECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 5509
Score = 66.5 bits (155), Expect = 4e-10
Identities = 28/65 (43%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 761 GRFRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
G +RCVC GYR G C D++EC P PC C NT GS+ C+C G L DG +
Sbjct: 5294 GSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKS 5353
Query: 819 CRDVD 823
C ++
Sbjct: 5354 CAGLE 5358
Score = 55.6 bits (128), Expect = 7e-07
Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC+ C+ C +T +QC C GY+ + C+D+DEC C C
Sbjct: 5433 IDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCF 5490
Query: 128 NLPGAFEC---RCPPGYRLTPSLDEC 150
N+ G+++C CPP Y+ P C
Sbjct: 5491 NMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Score = 52.8 bits (121), Expect = 5e-06
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 12/89 (13%)
Query: 743 DVFADVDECA---AIPGLCAP--GRFRCVCGPGYRPA--GEVCADVDECAVRPPPC--DQ 793
D D+DEC A C G ++C+C PGY+ G+ C D+DEC + C ++
Sbjct: 5428 DTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNR 5487
Query: 794 LCHNTDGSYDCL---CRTGYELDEDGANC 819
+C N GSY C+ C Y+ D C
Sbjct: 5488 MCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1. ).
Length = 5635
Score = 228 bits (558), Expect = 6e-59
Identities = 146/433 (33%), Positives = 196/433 (45%), Gaps = 36/433 (8%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C G+ D+ C D DEC+ G P C C N G + C CP G + C+D+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNP-CSH--SCHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 154 DECG-DQRICDHG-DCRNTIGSYRCECKPGYTLRENV----CRDVDECSRPRPVCRNGTC 207
DEC + C G DC NTIGSYRC + G R C+D++EC P C C
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RC 5206
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRC-ECAPGYTL 265
N G++ C C+ G++ C+DVNECR+ VCR + C+NT G ++C + P
Sbjct: 5207 FNAIGSFHCGCEPGYQL-KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNGMT 5263
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKE 323
A+ C D+DEC + H C N C NT G Y C C G++ VGR C+D +EC++
Sbjct: 5264 KAENGTCIDIDECKDGTHQCRY--NQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 5321
Query: 324 LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKE---LCYDEWEAGRCHRAR- 378
+P CA +C N G + C CP G C ER Y + R R
Sbjct: 5322 VPKPCA-HQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 5380
Query: 379 ---PLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC-QGGMGRPNLTQDLDECRVRP 434
P Q R + R + + C +G + D+DEC
Sbjct: 5381 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECE-NT 5439
Query: 435 DVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
D C C NT GS++C CP GY L +G +C D DEC CG N C N RG Y+C
Sbjct: 5440 DAC-QHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5498
Query: 494 ---QCSPGFTQGP 503
C P + + P
Sbjct: 5499 IDTPCPPNYQRDP 5511
Score = 208 bits (508), Expect = 6e-53
Identities = 156/457 (34%), Positives = 206/457 (45%), Gaps = 62/457 (13%)
Query: 177 ECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK-AGPNNDCVDV 233
+C G+TL C D DEC+ P C + +C N G Y C C G A C D+
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNP-CSH-SCHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 234 NECREGGMVCRNGR-CRNTVGSFRC--ECAPGYTLTADGRNCRDVDECDELPHPCGRDGN 290
+EC G C G+ C NT+GS+RC C G+ T+DG +C+D++EC E PC +
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSPC----H 5203
Query: 291 PSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVC--ECPAG 347
C N G + C C G++L GR+C+D +EC++ VC + C+N GGY C CP G
Sbjct: 5204 QRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNG 5261
Query: 348 WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS 407
+ C+D DE + G H+ R Q+ C G Y RC P
Sbjct: 5262 MTKAEN-GTCID------IDECKDG-THQCRYNQI------CEN--TRGSY--RCVCPRG 5303
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
G+GRP D++EC P C +C NT GSF+C CP G L DG SC
Sbjct: 5304 YR-----SQGVGRP--CMDINECEQVPKPC-AHQCSNTPGSFKCICPPGQHLLGDGKSCA 5355
Query: 468 DADEC---ALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
+ S R Y+ Q Q Q +E R S T
Sbjct: 5356 GLERLPNYGTQYSSYNLARFSPVRNNYQPQ------QHYRQYSHLYSSYSEYRNSRT-SL 5408
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
T + R TCP G + D C DIDEC + C H C+N GSY C CP GY+ T
Sbjct: 5409 SRTRRTIRKTCPEGSEASHD--TCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLT- 5464
Query: 585 APQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
+ C+DI+EC EQ C +C N GS+ C
Sbjct: 5465 ---HNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5498
Score = 197 bits (480), Expect = 2e-49
Identities = 133/425 (31%), Positives = 187/425 (44%), Gaps = 43/425 (10%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC--RCPP 139
+CH+ + C C G C+D+DEC+ GR C C N G++ C RC
Sbjct: 5120 SCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGS 5179
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPR 199
G+R T C+D++EC + C H C N IGS+ C C+PGY L+ C DV+EC +
Sbjct: 5180 GFRRTSDGLSCQDINECQESSPC-HQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQN- 5237
Query: 200 PVCR-NGTCENLPGAYLCH--CDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSF 255
VCR + C+N G Y C C +G N C+D++EC++G CR N C NT GS+
Sbjct: 5238 -VCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSY 5296
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
RC C GY GR C D++EC+++P PC C+NT G ++C C G L+G
Sbjct: 5297 RCVCPRGYRSQGVGRPCMDINECEQVPKPCAH----QCSNTPGSFKCICPPGQHLLG--- 5349
Query: 316 VDRDECKELPYV-CAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC 374
D C L + G + ++N P + Y E+ R
Sbjct: 5350 -DGKSCAGLERLPNYGTQYSSYN--LARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRT 5406
Query: 375 HRARPLQLARPECCCSEGAAWGRY--CERCPAPDSAE---------FMRICQGG---MGR 420
+R + R C A+ + C D+ + + IC G
Sbjct: 5407 SLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHN 5466
Query: 421 PNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC---ECPDGYVLAP-DGL---SCVDAD-E 471
QD+DEC + C R C N GS++C CP Y P G +C D E
Sbjct: 5467 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLE 5526
Query: 472 CALDP 476
CAL P
Sbjct: 5527 CALSP 5531
Score = 166 bits (403), Expect = 3e-40
Identities = 91/234 (38%), Positives = 118/234 (50%), Gaps = 19/234 (8%)
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVD 193
+CP G+ L C D DEC C H C N +G+Y C C G T+ + C+D+D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 194 ECSRPRPVCRNGT-CENLPGAYLC--HCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCR 249
EC+ R C G C+N G+Y C C GF+ + C D+NEC+E C RC
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCF 5207
Query: 250 NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS--CGAG 307
N +GSF C C PGY L GR C DV+EC + + C D + C NT GGY+C C G
Sbjct: 5208 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQ--NVCRPDQH--CKNTRGGYKCIDLCPNG 5261
Query: 308 W-KLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVD 359
K C+D DECK+ + C + C N G Y C CP G+R C+D
Sbjct: 5262 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMD 5315
Score = 156 bits (378), Expect = 4e-37
Identities = 115/323 (35%), Positives = 142/323 (43%), Gaps = 47/323 (14%)
Query: 343 ECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERC 402
+CP+G+ D C DE DE AG C S A G Y C
Sbjct: 5091 QCPSGFTLDSVGPFCADE------DECAAGN------------PCSHSCHNAMGTYYCSC 5132
Query: 403 PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC--ECPDGYVL 459
P + + I G QD+DEC + C G+ C NT GS+RC C G+
Sbjct: 5133 P-----KGLTIAADG----RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRR 5183
Query: 460 APDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS 519
DGLSC D +EC + C + C N G + C C PG+ Q + C+DV+EC +
Sbjct: 5184 TSDGLSCQDINECQ-ESSPC-HQRCFNAIGSFHCGCEPGY-QLKGRKCMDVNECRQNVCR 5240
Query: 520 CTFRCHNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPH--ACENVVGSYICK 575
C NT G ++C CP G A +G C DIDEC C + CEN GSY C
Sbjct: 5241 PDQHCKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCV 5299
Query: 576 CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
CP GYR Q C DINECE+ C+ C NT GSF C C G DG C
Sbjct: 5300 CPRGYRS----QGVGRPCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDGKSC 5354
Query: 636 --IDR--RTGTCYRSLVSGRCEP 654
++R GT Y S R P
Sbjct: 5355 AGLERLPNYGTQYSSYNLARFSP 5377
Score = 151 bits (365), Expect = 1e-35
Identities = 90/255 (35%), Positives = 124/255 (48%), Gaps = 20/255 (7%)
Query: 35 CEACPPRGSPAHTAL----CGEKPGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTG 89
C A P H A+ C G I + IDEC + C G C +T
Sbjct: 5111 CAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGS 5170
Query: 90 FQC--GCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
++C C G+ + C+D++EC P C +C N G+F C C PGY+L
Sbjct: 5171 YRCVVRCGSGFRRTSDGLSCQDINECQESSP-CH--QRCFNAIGSFHCGCEPGYQLKGR- 5226
Query: 148 DECEDVDECGDQRICDHGD-CRNTIGSYRCE--CKPGYTLREN-VCRDVDECSRPRPVCR 203
+C DV+EC Q +C C+NT G Y+C C G T EN C D+DEC CR
Sbjct: 5227 -KCMDVNECR-QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCR 5284
Query: 204 -NGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAP 261
N CEN G+Y C C G+++ G C+D+NEC + C + +C NT GSF+C C P
Sbjct: 5285 YNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPP 5343
Query: 262 GYTLTADGRNCRDVD 276
G L DG++C ++
Sbjct: 5344 GQHLLGDGKSCAGLE 5358
Score = 136 bits (328), Expect = 4e-31
Identities = 119/405 (29%), Positives = 164/405 (40%), Gaps = 48/405 (11%)
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRC 315
+C G+TL + G C D DEC +PC SC N G Y CSC G + GR C
Sbjct: 5091 QCPSGFTLDSVGPFCADEDEC-AAGNPCSH----SCHNAMGTYYCSCPKGLTIAADGRTC 5145
Query: 316 VDRDECKELPYVC-AGGECRNFNGGYVC--ECPAGWRFDKTAAVCVDERKELCYDEWEAG 372
D DEC + C AG +C N G Y C C +G+R C D + C E+
Sbjct: 5146 QDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINE--CQ---ESS 5200
Query: 373 RCHRARPLQLARPECCCSEGAAW-GRYC-------ERCPAPDSA--------EFMRICQG 416
CH+ + C C G GR C + PD + + +C
Sbjct: 5201 PCHQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPN 5260
Query: 417 GMGRPN--LTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
GM + D+DEC+ C + C NT GS+RC CP GY G C+D +EC
Sbjct: 5261 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECE 5320
Query: 474 LDPRICGNGTCSNTRGGYECQCSPG-FTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
P+ C + CSNT G ++C C PG G ++C ++ + +N A
Sbjct: 5321 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPN--YGTQYSSYNLARF-- 5375
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
Y + E R + + CPEG + S +
Sbjct: 5376 SPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEG------SEASHDT 5429
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+ECE D C C NT GS+ C C G++ + +G C D
Sbjct: 5430 CVDIDECENT-DACQHE-CKNTFGSYQCICPPGYQLTHNGKTCQD 5472
Score = 122 bits (295), Expect = 4e-27
Identities = 70/179 (39%), Positives = 94/179 (52%), Gaps = 16/179 (8%)
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTFR 523
S V++D ++ + S ++G QC GFT C D DECA G C+
Sbjct: 5062 SSVESDYNQIEETLGFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECAAGNP-CSHS 5120
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA---CENVVGSYIC--KCPE 578
CHN G++ C+CP G +AADG C+DIDEC C HA C+N +GSY C +C
Sbjct: 5121 CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTC-HAGQDCDNTIGSYRCVVRCGS 5179
Query: 579 GYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
G+RRTS +C+DINEC+E C C N GSF C C+ G++ G C+D
Sbjct: 5180 GFRRTS----DGLSCQDINECQESSP-CHQR-CFNAIGSFHCGCEPGYQLK--GRKCMD 5230
Score = 97.5 bits (232), Expect = 2e-19
Identities = 48/101 (47%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Query: 759 APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDC--LCRTGYELDEDG 816
A G F C C PGY+ G C DV+EC DQ C NT G Y C LC G E+G
Sbjct: 5209 AIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 5268
Query: 817 ANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRG 855
C D+DEC+ TH C+ QIC NT GSY C C GY +G
Sbjct: 5269 -TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQG 5308
Score = 94.7 bits (225), Expect = 1e-18
Identities = 51/125 (40%), Positives = 68/125 (54%), Gaps = 12/125 (9%)
Query: 746 ADVDECAA---IPGLC--APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCD--QLCH 796
AD DECAA C A G + C C G A G C D+DECA+ C Q C
Sbjct: 5106 ADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCD 5165
Query: 797 NTDGSYDCL--CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
NT GSY C+ C +G+ DG +C+D++EC+ ++ C Q C N GS+ C CE GY+ +
Sbjct: 5166 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 5224
Query: 855 GDACV 859
G C+
Sbjct: 5225 GRKCM 5229
Score = 85.4 bits (202), Expect = 8e-16
Identities = 41/97 (42%), Positives = 48/97 (49%), Gaps = 5/97 (5%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
+C G G CAD DECA P C CHN G+Y C C G + DG C+D+D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 824 ECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD 856
EC HTC Q C NT GSY C C G+ + D
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSD 5186
Score = 85.0 bits (201), Expect = 1e-15
Identities = 48/129 (37%), Positives = 63/129 (48%), Gaps = 17/129 (13%)
Query: 747 DVDECAAIPGLCAP--------GRFRCV--CGPGYRPAGE-VCADVDECAVRPPPC--DQ 793
DV+EC +C P G ++C+ C G A C D+DEC C +Q
Sbjct: 5230 DVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQ 5287
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
+C NT GSY C+C GY G C D++ECE+ C CSNT GS++C C G
Sbjct: 5288 ICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHL 5347
Query: 854 RGD--ACVG 860
GD +C G
Sbjct: 5348 LGDGKSCAG 5356
Score = 83.0 bits (196), Expect = 4e-15
Identities = 43/103 (41%), Positives = 58/103 (56%), Gaps = 7/103 (6%)
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
S TR C G ++ TCVD+DEC E +C C NT GS++C CP GY + +
Sbjct: 5409 SRTRRTIRKTCPEG-SEASHDTCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLTHN 5466
Query: 545 GVHCRDIDECVQEPRVC-PH-ACENVVGSYIC---KCPEGYRR 582
G C+DIDEC+++ C P+ C N+ GSY C CP Y+R
Sbjct: 5467 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 5509
Score = 79.4 bits (187), Expect = 5e-14
Identities = 36/95 (37%), Positives = 51/95 (53%), Gaps = 6/95 (6%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
R C G + + C D+DEC C C NT GSY C+C GY+L +G C+D+D
Sbjct: 5416 RKTCPEGSEASHDTCVDIDECE-NTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDID 5474
Query: 824 EC-ERDTHT-CQQICSNTEGSYEC---SCEDGYEK 853
EC E++ H ++C N GSY+C C Y++
Sbjct: 5475 ECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 5509
Score = 66.5 bits (155), Expect = 4e-10
Identities = 28/65 (43%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 761 GRFRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
G +RCVC GYR G C D++EC P PC C NT GS+ C+C G L DG +
Sbjct: 5294 GSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKS 5353
Query: 819 CRDVD 823
C ++
Sbjct: 5354 CAGLE 5358
Score = 55.6 bits (128), Expect = 7e-07
Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC+ C+ C +T +QC C GY+ + C+D+DEC C C
Sbjct: 5433 IDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCF 5490
Query: 128 NLPGAFEC---RCPPGYRLTPSLDEC 150
N+ G+++C CPP Y+ P C
Sbjct: 5491 NMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Score = 52.8 bits (121), Expect = 5e-06
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 12/89 (13%)
Query: 743 DVFADVDECA---AIPGLCAP--GRFRCVCGPGYRPA--GEVCADVDECAVRPPPC--DQ 793
D D+DEC A C G ++C+C PGY+ G+ C D+DEC + C ++
Sbjct: 5428 DTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNR 5487
Query: 794 LCHNTDGSYDCL---CRTGYELDEDGANC 819
+C N GSY C+ C Y+ D C
Sbjct: 5488 MCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1. ).
Length = 5635
Score = 228 bits (558), Expect = 6e-59
Identities = 146/433 (33%), Positives = 196/433 (45%), Gaps = 36/433 (8%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C G+ D+ C D DEC+ G P C C N G + C CP G + C+D+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNP-CSH--SCHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 154 DECG-DQRICDHG-DCRNTIGSYRCECKPGYTLRENV----CRDVDECSRPRPVCRNGTC 207
DEC + C G DC NTIGSYRC + G R C+D++EC P C C
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RC 5206
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRC-ECAPGYTL 265
N G++ C C+ G++ C+DVNECR+ VCR + C+NT G ++C + P
Sbjct: 5207 FNAIGSFHCGCEPGYQL-KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNGMT 5263
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKE 323
A+ C D+DEC + H C N C NT G Y C C G++ VGR C+D +EC++
Sbjct: 5264 KAENGTCIDIDECKDGTHQCRY--NQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 5321
Query: 324 LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKE---LCYDEWEAGRCHRAR- 378
+P CA +C N G + C CP G C ER Y + R R
Sbjct: 5322 VPKPCA-HQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 5380
Query: 379 ---PLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC-QGGMGRPNLTQDLDECRVRP 434
P Q R + R + + C +G + D+DEC
Sbjct: 5381 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECE-NT 5439
Query: 435 DVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
D C C NT GS++C CP GY L +G +C D DEC CG N C N RG Y+C
Sbjct: 5440 DAC-QHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5498
Query: 494 ---QCSPGFTQGP 503
C P + + P
Sbjct: 5499 IDTPCPPNYQRDP 5511
Score = 208 bits (508), Expect = 6e-53
Identities = 156/457 (34%), Positives = 206/457 (45%), Gaps = 62/457 (13%)
Query: 177 ECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK-AGPNNDCVDV 233
+C G+TL C D DEC+ P C + +C N G Y C C G A C D+
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNP-CSH-SCHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 234 NECREGGMVCRNGR-CRNTVGSFRC--ECAPGYTLTADGRNCRDVDECDELPHPCGRDGN 290
+EC G C G+ C NT+GS+RC C G+ T+DG +C+D++EC E PC +
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSPC----H 5203
Query: 291 PSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVC--ECPAG 347
C N G + C C G++L GR+C+D +EC++ VC + C+N GGY C CP G
Sbjct: 5204 QRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNG 5261
Query: 348 WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS 407
+ C+D DE + G H+ R Q+ C G Y RC P
Sbjct: 5262 MTKAEN-GTCID------IDECKDG-THQCRYNQI------CEN--TRGSY--RCVCPRG 5303
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
G+GRP D++EC P C +C NT GSF+C CP G L DG SC
Sbjct: 5304 YR-----SQGVGRP--CMDINECEQVPKPC-AHQCSNTPGSFKCICPPGQHLLGDGKSCA 5355
Query: 468 DADEC---ALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
+ S R Y+ Q Q Q +E R S T
Sbjct: 5356 GLERLPNYGTQYSSYNLARFSPVRNNYQPQ------QHYRQYSHLYSSYSEYRNSRT-SL 5408
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
T + R TCP G + D C DIDEC + C H C+N GSY C CP GY+ T
Sbjct: 5409 SRTRRTIRKTCPEGSEASHD--TCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLT- 5464
Query: 585 APQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
+ C+DI+EC EQ C +C N GS+ C
Sbjct: 5465 ---HNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5498
Score = 197 bits (480), Expect = 2e-49
Identities = 133/425 (31%), Positives = 187/425 (44%), Gaps = 43/425 (10%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC--RCPP 139
+CH+ + C C G C+D+DEC+ GR C C N G++ C RC
Sbjct: 5120 SCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGS 5179
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPR 199
G+R T C+D++EC + C H C N IGS+ C C+PGY L+ C DV+EC +
Sbjct: 5180 GFRRTSDGLSCQDINECQESSPC-HQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQN- 5237
Query: 200 PVCR-NGTCENLPGAYLCH--CDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSF 255
VCR + C+N G Y C C +G N C+D++EC++G CR N C NT GS+
Sbjct: 5238 -VCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSY 5296
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
RC C GY GR C D++EC+++P PC C+NT G ++C C G L+G
Sbjct: 5297 RCVCPRGYRSQGVGRPCMDINECEQVPKPCAH----QCSNTPGSFKCICPPGQHLLG--- 5349
Query: 316 VDRDECKELPYV-CAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC 374
D C L + G + ++N P + Y E+ R
Sbjct: 5350 -DGKSCAGLERLPNYGTQYSSYN--LARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRT 5406
Query: 375 HRARPLQLARPECCCSEGAAWGRY--CERCPAPDSAE---------FMRICQGG---MGR 420
+R + R C A+ + C D+ + + IC G
Sbjct: 5407 SLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHN 5466
Query: 421 PNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC---ECPDGYVLAP-DGL---SCVDAD-E 471
QD+DEC + C R C N GS++C CP Y P G +C D E
Sbjct: 5467 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLE 5526
Query: 472 CALDP 476
CAL P
Sbjct: 5527 CALSP 5531
Score = 166 bits (403), Expect = 3e-40
Identities = 91/234 (38%), Positives = 118/234 (50%), Gaps = 19/234 (8%)
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVD 193
+CP G+ L C D DEC C H C N +G+Y C C G T+ + C+D+D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 194 ECSRPRPVCRNGT-CENLPGAYLC--HCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCR 249
EC+ R C G C+N G+Y C C GF+ + C D+NEC+E C RC
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCF 5207
Query: 250 NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS--CGAG 307
N +GSF C C PGY L GR C DV+EC + + C D + C NT GGY+C C G
Sbjct: 5208 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQ--NVCRPDQH--CKNTRGGYKCIDLCPNG 5261
Query: 308 W-KLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVD 359
K C+D DECK+ + C + C N G Y C CP G+R C+D
Sbjct: 5262 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMD 5315
Score = 156 bits (378), Expect = 4e-37
Identities = 115/323 (35%), Positives = 142/323 (43%), Gaps = 47/323 (14%)
Query: 343 ECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERC 402
+CP+G+ D C DE DE AG C S A G Y C
Sbjct: 5091 QCPSGFTLDSVGPFCADE------DECAAGN------------PCSHSCHNAMGTYYCSC 5132
Query: 403 PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC--ECPDGYVL 459
P + + I G QD+DEC + C G+ C NT GS+RC C G+
Sbjct: 5133 P-----KGLTIAADG----RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRR 5183
Query: 460 APDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS 519
DGLSC D +EC + C + C N G + C C PG+ Q + C+DV+EC +
Sbjct: 5184 TSDGLSCQDINECQ-ESSPC-HQRCFNAIGSFHCGCEPGY-QLKGRKCMDVNECRQNVCR 5240
Query: 520 CTFRCHNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPH--ACENVVGSYICK 575
C NT G ++C CP G A +G C DIDEC C + CEN GSY C
Sbjct: 5241 PDQHCKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCV 5299
Query: 576 CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
CP GYR Q C DINECE+ C+ C NT GSF C C G DG C
Sbjct: 5300 CPRGYRS----QGVGRPCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDGKSC 5354
Query: 636 --IDR--RTGTCYRSLVSGRCEP 654
++R GT Y S R P
Sbjct: 5355 AGLERLPNYGTQYSSYNLARFSP 5377
Score = 151 bits (365), Expect = 1e-35
Identities = 90/255 (35%), Positives = 124/255 (48%), Gaps = 20/255 (7%)
Query: 35 CEACPPRGSPAHTAL----CGEKPGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTG 89
C A P H A+ C G I + IDEC + C G C +T
Sbjct: 5111 CAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGS 5170
Query: 90 FQC--GCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
++C C G+ + C+D++EC P C +C N G+F C C PGY+L
Sbjct: 5171 YRCVVRCGSGFRRTSDGLSCQDINECQESSP-CH--QRCFNAIGSFHCGCEPGYQLKGR- 5226
Query: 148 DECEDVDECGDQRICDHGD-CRNTIGSYRCE--CKPGYTLREN-VCRDVDECSRPRPVCR 203
+C DV+EC Q +C C+NT G Y+C C G T EN C D+DEC CR
Sbjct: 5227 -KCMDVNECR-QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCR 5284
Query: 204 -NGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAP 261
N CEN G+Y C C G+++ G C+D+NEC + C + +C NT GSF+C C P
Sbjct: 5285 YNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPP 5343
Query: 262 GYTLTADGRNCRDVD 276
G L DG++C ++
Sbjct: 5344 GQHLLGDGKSCAGLE 5358
Score = 136 bits (328), Expect = 4e-31
Identities = 119/405 (29%), Positives = 164/405 (40%), Gaps = 48/405 (11%)
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRC 315
+C G+TL + G C D DEC +PC SC N G Y CSC G + GR C
Sbjct: 5091 QCPSGFTLDSVGPFCADEDEC-AAGNPCSH----SCHNAMGTYYCSCPKGLTIAADGRTC 5145
Query: 316 VDRDECKELPYVC-AGGECRNFNGGYVC--ECPAGWRFDKTAAVCVDERKELCYDEWEAG 372
D DEC + C AG +C N G Y C C +G+R C D + C E+
Sbjct: 5146 QDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINE--CQ---ESS 5200
Query: 373 RCHRARPLQLARPECCCSEGAAW-GRYC-------ERCPAPDSA--------EFMRICQG 416
CH+ + C C G GR C + PD + + +C
Sbjct: 5201 PCHQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPN 5260
Query: 417 GMGRPN--LTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
GM + D+DEC+ C + C NT GS+RC CP GY G C+D +EC
Sbjct: 5261 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECE 5320
Query: 474 LDPRICGNGTCSNTRGGYECQCSPG-FTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
P+ C + CSNT G ++C C PG G ++C ++ + +N A
Sbjct: 5321 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPN--YGTQYSSYNLARF-- 5375
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
Y + E R + + CPEG + S +
Sbjct: 5376 SPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEG------SEASHDT 5429
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+ECE D C C NT GS+ C C G++ + +G C D
Sbjct: 5430 CVDIDECENT-DACQHE-CKNTFGSYQCICPPGYQLTHNGKTCQD 5472
Score = 122 bits (295), Expect = 4e-27
Identities = 70/179 (39%), Positives = 94/179 (52%), Gaps = 16/179 (8%)
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTFR 523
S V++D ++ + S ++G QC GFT C D DECA G C+
Sbjct: 5062 SSVESDYNQIEETLGFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECAAGNP-CSHS 5120
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA---CENVVGSYIC--KCPE 578
CHN G++ C+CP G +AADG C+DIDEC C HA C+N +GSY C +C
Sbjct: 5121 CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTC-HAGQDCDNTIGSYRCVVRCGS 5179
Query: 579 GYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
G+RRTS +C+DINEC+E C C N GSF C C+ G++ G C+D
Sbjct: 5180 GFRRTS----DGLSCQDINECQESSP-CHQR-CFNAIGSFHCGCEPGYQLK--GRKCMD 5230
Score = 97.5 bits (232), Expect = 2e-19
Identities = 48/101 (47%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Query: 759 APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDC--LCRTGYELDEDG 816
A G F C C PGY+ G C DV+EC DQ C NT G Y C LC G E+G
Sbjct: 5209 AIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 5268
Query: 817 ANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRG 855
C D+DEC+ TH C+ QIC NT GSY C C GY +G
Sbjct: 5269 -TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQG 5308
Score = 94.7 bits (225), Expect = 1e-18
Identities = 51/125 (40%), Positives = 68/125 (54%), Gaps = 12/125 (9%)
Query: 746 ADVDECAA---IPGLC--APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCD--QLCH 796
AD DECAA C A G + C C G A G C D+DECA+ C Q C
Sbjct: 5106 ADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCD 5165
Query: 797 NTDGSYDCL--CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
NT GSY C+ C +G+ DG +C+D++EC+ ++ C Q C N GS+ C CE GY+ +
Sbjct: 5166 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 5224
Query: 855 GDACV 859
G C+
Sbjct: 5225 GRKCM 5229
Score = 85.4 bits (202), Expect = 8e-16
Identities = 41/97 (42%), Positives = 48/97 (49%), Gaps = 5/97 (5%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
+C G G CAD DECA P C CHN G+Y C C G + DG C+D+D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 824 ECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD 856
EC HTC Q C NT GSY C C G+ + D
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSD 5186
Score = 85.0 bits (201), Expect = 1e-15
Identities = 48/129 (37%), Positives = 63/129 (48%), Gaps = 17/129 (13%)
Query: 747 DVDECAAIPGLCAP--------GRFRCV--CGPGYRPAGE-VCADVDECAVRPPPC--DQ 793
DV+EC +C P G ++C+ C G A C D+DEC C +Q
Sbjct: 5230 DVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQ 5287
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
+C NT GSY C+C GY G C D++ECE+ C CSNT GS++C C G
Sbjct: 5288 ICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHL 5347
Query: 854 RGD--ACVG 860
GD +C G
Sbjct: 5348 LGDGKSCAG 5356
Score = 83.0 bits (196), Expect = 4e-15
Identities = 43/103 (41%), Positives = 58/103 (56%), Gaps = 7/103 (6%)
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
S TR C G ++ TCVD+DEC E +C C NT GS++C CP GY + +
Sbjct: 5409 SRTRRTIRKTCPEG-SEASHDTCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLTHN 5466
Query: 545 GVHCRDIDECVQEPRVC-PH-ACENVVGSYIC---KCPEGYRR 582
G C+DIDEC+++ C P+ C N+ GSY C CP Y+R
Sbjct: 5467 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 5509
Score = 79.4 bits (187), Expect = 5e-14
Identities = 36/95 (37%), Positives = 51/95 (53%), Gaps = 6/95 (6%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
R C G + + C D+DEC C C NT GSY C+C GY+L +G C+D+D
Sbjct: 5416 RKTCPEGSEASHDTCVDIDECE-NTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDID 5474
Query: 824 EC-ERDTHT-CQQICSNTEGSYEC---SCEDGYEK 853
EC E++ H ++C N GSY+C C Y++
Sbjct: 5475 ECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 5509
Score = 66.5 bits (155), Expect = 4e-10
Identities = 28/65 (43%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 761 GRFRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
G +RCVC GYR G C D++EC P PC C NT GS+ C+C G L DG +
Sbjct: 5294 GSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKS 5353
Query: 819 CRDVD 823
C ++
Sbjct: 5354 CAGLE 5358
Score = 55.6 bits (128), Expect = 7e-07
Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC+ C+ C +T +QC C GY+ + C+D+DEC C C
Sbjct: 5433 IDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCF 5490
Query: 128 NLPGAFEC---RCPPGYRLTPSLDEC 150
N+ G+++C CPP Y+ P C
Sbjct: 5491 NMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Score = 52.8 bits (121), Expect = 5e-06
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 12/89 (13%)
Query: 743 DVFADVDECA---AIPGLCAP--GRFRCVCGPGYRPA--GEVCADVDECAVRPPPC--DQ 793
D D+DEC A C G ++C+C PGY+ G+ C D+DEC + C ++
Sbjct: 5428 DTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNR 5487
Query: 794 LCHNTDGSYDCL---CRTGYELDEDGANC 819
+C N GSY C+ C Y+ D C
Sbjct: 5488 MCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
Length = 5635
Score = 228 bits (558), Expect = 6e-59
Identities = 146/433 (33%), Positives = 196/433 (45%), Gaps = 36/433 (8%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C G+ D+ C D DEC+ G P C C N G + C CP G + C+D+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNP-CSH--SCHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 154 DECG-DQRICDHG-DCRNTIGSYRCECKPGYTLRENV----CRDVDECSRPRPVCRNGTC 207
DEC + C G DC NTIGSYRC + G R C+D++EC P C C
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RC 5206
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRC-ECAPGYTL 265
N G++ C C+ G++ C+DVNECR+ VCR + C+NT G ++C + P
Sbjct: 5207 FNAIGSFHCGCEPGYQL-KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNGMT 5263
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKE 323
A+ C D+DEC + H C N C NT G Y C C G++ VGR C+D +EC++
Sbjct: 5264 KAENGTCIDIDECKDGTHQCRY--NQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 5321
Query: 324 LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKE---LCYDEWEAGRCHRAR- 378
+P CA +C N G + C CP G C ER Y + R R
Sbjct: 5322 VPKPCA-HQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 5380
Query: 379 ---PLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC-QGGMGRPNLTQDLDECRVRP 434
P Q R + R + + C +G + D+DEC
Sbjct: 5381 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECE-NT 5439
Query: 435 DVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
D C C NT GS++C CP GY L +G +C D DEC CG N C N RG Y+C
Sbjct: 5440 DAC-QHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5498
Query: 494 ---QCSPGFTQGP 503
C P + + P
Sbjct: 5499 IDTPCPPNYQRDP 5511
Score = 208 bits (508), Expect = 6e-53
Identities = 156/457 (34%), Positives = 206/457 (45%), Gaps = 62/457 (13%)
Query: 177 ECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK-AGPNNDCVDV 233
+C G+TL C D DEC+ P C + +C N G Y C C G A C D+
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNP-CSH-SCHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 234 NECREGGMVCRNGR-CRNTVGSFRC--ECAPGYTLTADGRNCRDVDECDELPHPCGRDGN 290
+EC G C G+ C NT+GS+RC C G+ T+DG +C+D++EC E PC +
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSPC----H 5203
Query: 291 PSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVC--ECPAG 347
C N G + C C G++L GR+C+D +EC++ VC + C+N GGY C CP G
Sbjct: 5204 QRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNG 5261
Query: 348 WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS 407
+ C+D DE + G H+ R Q+ C G Y RC P
Sbjct: 5262 MTKAEN-GTCID------IDECKDG-THQCRYNQI------CEN--TRGSY--RCVCPRG 5303
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
G+GRP D++EC P C +C NT GSF+C CP G L DG SC
Sbjct: 5304 YR-----SQGVGRP--CMDINECEQVPKPC-AHQCSNTPGSFKCICPPGQHLLGDGKSCA 5355
Query: 468 DADEC---ALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
+ S R Y+ Q Q Q +E R S T
Sbjct: 5356 GLERLPNYGTQYSSYNLARFSPVRNNYQPQ------QHYRQYSHLYSSYSEYRNSRT-SL 5408
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
T + R TCP G + D C DIDEC + C H C+N GSY C CP GY+ T
Sbjct: 5409 SRTRRTIRKTCPEGSEASHD--TCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLT- 5464
Query: 585 APQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
+ C+DI+EC EQ C +C N GS+ C
Sbjct: 5465 ---HNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5498
Score = 197 bits (480), Expect = 2e-49
Identities = 133/425 (31%), Positives = 187/425 (44%), Gaps = 43/425 (10%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC--RCPP 139
+CH+ + C C G C+D+DEC+ GR C C N G++ C RC
Sbjct: 5120 SCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGS 5179
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPR 199
G+R T C+D++EC + C H C N IGS+ C C+PGY L+ C DV+EC +
Sbjct: 5180 GFRRTSDGLSCQDINECQESSPC-HQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQN- 5237
Query: 200 PVCR-NGTCENLPGAYLCH--CDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSF 255
VCR + C+N G Y C C +G N C+D++EC++G CR N C NT GS+
Sbjct: 5238 -VCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSY 5296
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
RC C GY GR C D++EC+++P PC C+NT G ++C C G L+G
Sbjct: 5297 RCVCPRGYRSQGVGRPCMDINECEQVPKPCAH----QCSNTPGSFKCICPPGQHLLG--- 5349
Query: 316 VDRDECKELPYV-CAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC 374
D C L + G + ++N P + Y E+ R
Sbjct: 5350 -DGKSCAGLERLPNYGTQYSSYN--LARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRT 5406
Query: 375 HRARPLQLARPECCCSEGAAWGRY--CERCPAPDSAE---------FMRICQGG---MGR 420
+R + R C A+ + C D+ + + IC G
Sbjct: 5407 SLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHN 5466
Query: 421 PNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC---ECPDGYVLAP-DGL---SCVDAD-E 471
QD+DEC + C R C N GS++C CP Y P G +C D E
Sbjct: 5467 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLE 5526
Query: 472 CALDP 476
CAL P
Sbjct: 5527 CALSP 5531
Score = 166 bits (403), Expect = 3e-40
Identities = 91/234 (38%), Positives = 118/234 (50%), Gaps = 19/234 (8%)
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVD 193
+CP G+ L C D DEC C H C N +G+Y C C G T+ + C+D+D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 194 ECSRPRPVCRNGT-CENLPGAYLC--HCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCR 249
EC+ R C G C+N G+Y C C GF+ + C D+NEC+E C RC
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCF 5207
Query: 250 NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS--CGAG 307
N +GSF C C PGY L GR C DV+EC + + C D + C NT GGY+C C G
Sbjct: 5208 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQ--NVCRPDQH--CKNTRGGYKCIDLCPNG 5261
Query: 308 W-KLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVD 359
K C+D DECK+ + C + C N G Y C CP G+R C+D
Sbjct: 5262 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMD 5315
Score = 156 bits (378), Expect = 4e-37
Identities = 115/323 (35%), Positives = 142/323 (43%), Gaps = 47/323 (14%)
Query: 343 ECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERC 402
+CP+G+ D C DE DE AG C S A G Y C
Sbjct: 5091 QCPSGFTLDSVGPFCADE------DECAAGN------------PCSHSCHNAMGTYYCSC 5132
Query: 403 PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC--ECPDGYVL 459
P + + I G QD+DEC + C G+ C NT GS+RC C G+
Sbjct: 5133 P-----KGLTIAADG----RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRR 5183
Query: 460 APDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS 519
DGLSC D +EC + C + C N G + C C PG+ Q + C+DV+EC +
Sbjct: 5184 TSDGLSCQDINECQ-ESSPC-HQRCFNAIGSFHCGCEPGY-QLKGRKCMDVNECRQNVCR 5240
Query: 520 CTFRCHNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPH--ACENVVGSYICK 575
C NT G ++C CP G A +G C DIDEC C + CEN GSY C
Sbjct: 5241 PDQHCKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCV 5299
Query: 576 CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
CP GYR Q C DINECE+ C+ C NT GSF C C G DG C
Sbjct: 5300 CPRGYRS----QGVGRPCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDGKSC 5354
Query: 636 --IDR--RTGTCYRSLVSGRCEP 654
++R GT Y S R P
Sbjct: 5355 AGLERLPNYGTQYSSYNLARFSP 5377
Score = 151 bits (365), Expect = 1e-35
Identities = 90/255 (35%), Positives = 124/255 (48%), Gaps = 20/255 (7%)
Query: 35 CEACPPRGSPAHTAL----CGEKPGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTG 89
C A P H A+ C G I + IDEC + C G C +T
Sbjct: 5111 CAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGS 5170
Query: 90 FQC--GCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
++C C G+ + C+D++EC P C +C N G+F C C PGY+L
Sbjct: 5171 YRCVVRCGSGFRRTSDGLSCQDINECQESSP-CH--QRCFNAIGSFHCGCEPGYQLKGR- 5226
Query: 148 DECEDVDECGDQRICDHGD-CRNTIGSYRCE--CKPGYTLREN-VCRDVDECSRPRPVCR 203
+C DV+EC Q +C C+NT G Y+C C G T EN C D+DEC CR
Sbjct: 5227 -KCMDVNECR-QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCR 5284
Query: 204 -NGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAP 261
N CEN G+Y C C G+++ G C+D+NEC + C + +C NT GSF+C C P
Sbjct: 5285 YNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPP 5343
Query: 262 GYTLTADGRNCRDVD 276
G L DG++C ++
Sbjct: 5344 GQHLLGDGKSCAGLE 5358
Score = 136 bits (328), Expect = 4e-31
Identities = 119/405 (29%), Positives = 164/405 (40%), Gaps = 48/405 (11%)
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRC 315
+C G+TL + G C D DEC +PC SC N G Y CSC G + GR C
Sbjct: 5091 QCPSGFTLDSVGPFCADEDEC-AAGNPCSH----SCHNAMGTYYCSCPKGLTIAADGRTC 5145
Query: 316 VDRDECKELPYVC-AGGECRNFNGGYVC--ECPAGWRFDKTAAVCVDERKELCYDEWEAG 372
D DEC + C AG +C N G Y C C +G+R C D + C E+
Sbjct: 5146 QDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINE--CQ---ESS 5200
Query: 373 RCHRARPLQLARPECCCSEGAAW-GRYC-------ERCPAPDSA--------EFMRICQG 416
CH+ + C C G GR C + PD + + +C
Sbjct: 5201 PCHQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPN 5260
Query: 417 GMGRPN--LTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
GM + D+DEC+ C + C NT GS+RC CP GY G C+D +EC
Sbjct: 5261 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECE 5320
Query: 474 LDPRICGNGTCSNTRGGYECQCSPG-FTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
P+ C + CSNT G ++C C PG G ++C ++ + +N A
Sbjct: 5321 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPN--YGTQYSSYNLARF-- 5375
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
Y + E R + + CPEG + S +
Sbjct: 5376 SPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEG------SEASHDT 5429
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+ECE D C C NT GS+ C C G++ + +G C D
Sbjct: 5430 CVDIDECENT-DACQHE-CKNTFGSYQCICPPGYQLTHNGKTCQD 5472
Score = 122 bits (295), Expect = 4e-27
Identities = 70/179 (39%), Positives = 94/179 (52%), Gaps = 16/179 (8%)
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTFR 523
S V++D ++ + S ++G QC GFT C D DECA G C+
Sbjct: 5062 SSVESDYNQIEETLGFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECAAGNP-CSHS 5120
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA---CENVVGSYIC--KCPE 578
CHN G++ C+CP G +AADG C+DIDEC C HA C+N +GSY C +C
Sbjct: 5121 CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTC-HAGQDCDNTIGSYRCVVRCGS 5179
Query: 579 GYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
G+RRTS +C+DINEC+E C C N GSF C C+ G++ G C+D
Sbjct: 5180 GFRRTS----DGLSCQDINECQESSP-CHQR-CFNAIGSFHCGCEPGYQLK--GRKCMD 5230
Score = 97.5 bits (232), Expect = 2e-19
Identities = 48/101 (47%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Query: 759 APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDC--LCRTGYELDEDG 816
A G F C C PGY+ G C DV+EC DQ C NT G Y C LC G E+G
Sbjct: 5209 AIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 5268
Query: 817 ANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRG 855
C D+DEC+ TH C+ QIC NT GSY C C GY +G
Sbjct: 5269 -TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQG 5308
Score = 94.7 bits (225), Expect = 1e-18
Identities = 51/125 (40%), Positives = 68/125 (54%), Gaps = 12/125 (9%)
Query: 746 ADVDECAA---IPGLC--APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCD--QLCH 796
AD DECAA C A G + C C G A G C D+DECA+ C Q C
Sbjct: 5106 ADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCD 5165
Query: 797 NTDGSYDCL--CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
NT GSY C+ C +G+ DG +C+D++EC+ ++ C Q C N GS+ C CE GY+ +
Sbjct: 5166 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 5224
Query: 855 GDACV 859
G C+
Sbjct: 5225 GRKCM 5229
Score = 85.4 bits (202), Expect = 8e-16
Identities = 41/97 (42%), Positives = 48/97 (49%), Gaps = 5/97 (5%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
+C G G CAD DECA P C CHN G+Y C C G + DG C+D+D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 824 ECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD 856
EC HTC Q C NT GSY C C G+ + D
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSD 5186
Score = 85.0 bits (201), Expect = 1e-15
Identities = 48/129 (37%), Positives = 63/129 (48%), Gaps = 17/129 (13%)
Query: 747 DVDECAAIPGLCAP--------GRFRCV--CGPGYRPAGE-VCADVDECAVRPPPC--DQ 793
DV+EC +C P G ++C+ C G A C D+DEC C +Q
Sbjct: 5230 DVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQ 5287
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
+C NT GSY C+C GY G C D++ECE+ C CSNT GS++C C G
Sbjct: 5288 ICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHL 5347
Query: 854 RGD--ACVG 860
GD +C G
Sbjct: 5348 LGDGKSCAG 5356
Score = 83.0 bits (196), Expect = 4e-15
Identities = 43/103 (41%), Positives = 58/103 (56%), Gaps = 7/103 (6%)
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
S TR C G ++ TCVD+DEC E +C C NT GS++C CP GY + +
Sbjct: 5409 SRTRRTIRKTCPEG-SEASHDTCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLTHN 5466
Query: 545 GVHCRDIDECVQEPRVC-PH-ACENVVGSYIC---KCPEGYRR 582
G C+DIDEC+++ C P+ C N+ GSY C CP Y+R
Sbjct: 5467 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 5509
Score = 79.4 bits (187), Expect = 5e-14
Identities = 36/95 (37%), Positives = 51/95 (53%), Gaps = 6/95 (6%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
R C G + + C D+DEC C C NT GSY C+C GY+L +G C+D+D
Sbjct: 5416 RKTCPEGSEASHDTCVDIDECE-NTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDID 5474
Query: 824 EC-ERDTHT-CQQICSNTEGSYEC---SCEDGYEK 853
EC E++ H ++C N GSY+C C Y++
Sbjct: 5475 ECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 5509
Score = 66.5 bits (155), Expect = 4e-10
Identities = 28/65 (43%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 761 GRFRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
G +RCVC GYR G C D++EC P PC C NT GS+ C+C G L DG +
Sbjct: 5294 GSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKS 5353
Query: 819 CRDVD 823
C ++
Sbjct: 5354 CAGLE 5358
Score = 55.6 bits (128), Expect = 7e-07
Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC+ C+ C +T +QC C GY+ + C+D+DEC C C
Sbjct: 5433 IDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCF 5490
Query: 128 NLPGAFEC---RCPPGYRLTPSLDEC 150
N+ G+++C CPP Y+ P C
Sbjct: 5491 NMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Score = 52.8 bits (121), Expect = 5e-06
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 12/89 (13%)
Query: 743 DVFADVDECA---AIPGLCAP--GRFRCVCGPGYRPA--GEVCADVDECAVRPPPC--DQ 793
D D+DEC A C G ++C+C PGY+ G+ C D+DEC + C ++
Sbjct: 5428 DTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNR 5487
Query: 794 LCHNTDGSYDCL---CRTGYELDEDGANC 819
+C N GSY C+ C Y+ D C
Sbjct: 5488 MCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
Length = 5635
Score = 228 bits (558), Expect = 6e-59
Identities = 146/433 (33%), Positives = 196/433 (45%), Gaps = 36/433 (8%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C G+ D+ C D DEC+ G P C C N G + C CP G + C+D+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNP-CSH--SCHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 154 DECG-DQRICDHG-DCRNTIGSYRCECKPGYTLRENV----CRDVDECSRPRPVCRNGTC 207
DEC + C G DC NTIGSYRC + G R C+D++EC P C C
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RC 5206
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRC-ECAPGYTL 265
N G++ C C+ G++ C+DVNECR+ VCR + C+NT G ++C + P
Sbjct: 5207 FNAIGSFHCGCEPGYQL-KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNGMT 5263
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKE 323
A+ C D+DEC + H C N C NT G Y C C G++ VGR C+D +EC++
Sbjct: 5264 KAENGTCIDIDECKDGTHQCRY--NQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 5321
Query: 324 LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKE---LCYDEWEAGRCHRAR- 378
+P CA +C N G + C CP G C ER Y + R R
Sbjct: 5322 VPKPCA-HQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 5380
Query: 379 ---PLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC-QGGMGRPNLTQDLDECRVRP 434
P Q R + R + + C +G + D+DEC
Sbjct: 5381 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECE-NT 5439
Query: 435 DVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
D C C NT GS++C CP GY L +G +C D DEC CG N C N RG Y+C
Sbjct: 5440 DAC-QHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5498
Query: 494 ---QCSPGFTQGP 503
C P + + P
Sbjct: 5499 IDTPCPPNYQRDP 5511
Score = 208 bits (508), Expect = 6e-53
Identities = 156/457 (34%), Positives = 206/457 (45%), Gaps = 62/457 (13%)
Query: 177 ECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK-AGPNNDCVDV 233
+C G+TL C D DEC+ P C + +C N G Y C C G A C D+
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNP-CSH-SCHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 234 NECREGGMVCRNGR-CRNTVGSFRC--ECAPGYTLTADGRNCRDVDECDELPHPCGRDGN 290
+EC G C G+ C NT+GS+RC C G+ T+DG +C+D++EC E PC +
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSPC----H 5203
Query: 291 PSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVC--ECPAG 347
C N G + C C G++L GR+C+D +EC++ VC + C+N GGY C CP G
Sbjct: 5204 QRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNG 5261
Query: 348 WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS 407
+ C+D DE + G H+ R Q+ C G Y RC P
Sbjct: 5262 MTKAEN-GTCID------IDECKDG-THQCRYNQI------CEN--TRGSY--RCVCPRG 5303
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
G+GRP D++EC P C +C NT GSF+C CP G L DG SC
Sbjct: 5304 YR-----SQGVGRP--CMDINECEQVPKPC-AHQCSNTPGSFKCICPPGQHLLGDGKSCA 5355
Query: 468 DADEC---ALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
+ S R Y+ Q Q Q +E R S T
Sbjct: 5356 GLERLPNYGTQYSSYNLARFSPVRNNYQPQ------QHYRQYSHLYSSYSEYRNSRT-SL 5408
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
T + R TCP G + D C DIDEC + C H C+N GSY C CP GY+ T
Sbjct: 5409 SRTRRTIRKTCPEGSEASHD--TCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLT- 5464
Query: 585 APQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
+ C+DI+EC EQ C +C N GS+ C
Sbjct: 5465 ---HNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5498
Score = 197 bits (480), Expect = 2e-49
Identities = 133/425 (31%), Positives = 187/425 (44%), Gaps = 43/425 (10%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC--RCPP 139
+CH+ + C C G C+D+DEC+ GR C C N G++ C RC
Sbjct: 5120 SCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGS 5179
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPR 199
G+R T C+D++EC + C H C N IGS+ C C+PGY L+ C DV+EC +
Sbjct: 5180 GFRRTSDGLSCQDINECQESSPC-HQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQN- 5237
Query: 200 PVCR-NGTCENLPGAYLCH--CDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSF 255
VCR + C+N G Y C C +G N C+D++EC++G CR N C NT GS+
Sbjct: 5238 -VCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSY 5296
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
RC C GY GR C D++EC+++P PC C+NT G ++C C G L+G
Sbjct: 5297 RCVCPRGYRSQGVGRPCMDINECEQVPKPCAH----QCSNTPGSFKCICPPGQHLLG--- 5349
Query: 316 VDRDECKELPYV-CAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC 374
D C L + G + ++N P + Y E+ R
Sbjct: 5350 -DGKSCAGLERLPNYGTQYSSYN--LARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRT 5406
Query: 375 HRARPLQLARPECCCSEGAAWGRY--CERCPAPDSAE---------FMRICQGG---MGR 420
+R + R C A+ + C D+ + + IC G
Sbjct: 5407 SLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHN 5466
Query: 421 PNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC---ECPDGYVLAP-DGL---SCVDAD-E 471
QD+DEC + C R C N GS++C CP Y P G +C D E
Sbjct: 5467 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLE 5526
Query: 472 CALDP 476
CAL P
Sbjct: 5527 CALSP 5531
Score = 166 bits (403), Expect = 3e-40
Identities = 91/234 (38%), Positives = 118/234 (50%), Gaps = 19/234 (8%)
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVD 193
+CP G+ L C D DEC C H C N +G+Y C C G T+ + C+D+D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 194 ECSRPRPVCRNGT-CENLPGAYLC--HCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCR 249
EC+ R C G C+N G+Y C C GF+ + C D+NEC+E C RC
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCF 5207
Query: 250 NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS--CGAG 307
N +GSF C C PGY L GR C DV+EC + + C D + C NT GGY+C C G
Sbjct: 5208 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQ--NVCRPDQH--CKNTRGGYKCIDLCPNG 5261
Query: 308 W-KLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVD 359
K C+D DECK+ + C + C N G Y C CP G+R C+D
Sbjct: 5262 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMD 5315
Score = 156 bits (378), Expect = 4e-37
Identities = 115/323 (35%), Positives = 142/323 (43%), Gaps = 47/323 (14%)
Query: 343 ECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERC 402
+CP+G+ D C DE DE AG C S A G Y C
Sbjct: 5091 QCPSGFTLDSVGPFCADE------DECAAGN------------PCSHSCHNAMGTYYCSC 5132
Query: 403 PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC--ECPDGYVL 459
P + + I G QD+DEC + C G+ C NT GS+RC C G+
Sbjct: 5133 P-----KGLTIAADG----RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRR 5183
Query: 460 APDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS 519
DGLSC D +EC + C + C N G + C C PG+ Q + C+DV+EC +
Sbjct: 5184 TSDGLSCQDINECQ-ESSPC-HQRCFNAIGSFHCGCEPGY-QLKGRKCMDVNECRQNVCR 5240
Query: 520 CTFRCHNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPH--ACENVVGSYICK 575
C NT G ++C CP G A +G C DIDEC C + CEN GSY C
Sbjct: 5241 PDQHCKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCV 5299
Query: 576 CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
CP GYR Q C DINECE+ C+ C NT GSF C C G DG C
Sbjct: 5300 CPRGYRS----QGVGRPCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDGKSC 5354
Query: 636 --IDR--RTGTCYRSLVSGRCEP 654
++R GT Y S R P
Sbjct: 5355 AGLERLPNYGTQYSSYNLARFSP 5377
Score = 151 bits (365), Expect = 1e-35
Identities = 90/255 (35%), Positives = 124/255 (48%), Gaps = 20/255 (7%)
Query: 35 CEACPPRGSPAHTAL----CGEKPGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTG 89
C A P H A+ C G I + IDEC + C G C +T
Sbjct: 5111 CAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGS 5170
Query: 90 FQC--GCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
++C C G+ + C+D++EC P C +C N G+F C C PGY+L
Sbjct: 5171 YRCVVRCGSGFRRTSDGLSCQDINECQESSP-CH--QRCFNAIGSFHCGCEPGYQLKGR- 5226
Query: 148 DECEDVDECGDQRICDHGD-CRNTIGSYRCE--CKPGYTLREN-VCRDVDECSRPRPVCR 203
+C DV+EC Q +C C+NT G Y+C C G T EN C D+DEC CR
Sbjct: 5227 -KCMDVNECR-QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCR 5284
Query: 204 -NGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAP 261
N CEN G+Y C C G+++ G C+D+NEC + C + +C NT GSF+C C P
Sbjct: 5285 YNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPP 5343
Query: 262 GYTLTADGRNCRDVD 276
G L DG++C ++
Sbjct: 5344 GQHLLGDGKSCAGLE 5358
Score = 136 bits (328), Expect = 4e-31
Identities = 119/405 (29%), Positives = 164/405 (40%), Gaps = 48/405 (11%)
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRC 315
+C G+TL + G C D DEC +PC SC N G Y CSC G + GR C
Sbjct: 5091 QCPSGFTLDSVGPFCADEDEC-AAGNPCSH----SCHNAMGTYYCSCPKGLTIAADGRTC 5145
Query: 316 VDRDECKELPYVC-AGGECRNFNGGYVC--ECPAGWRFDKTAAVCVDERKELCYDEWEAG 372
D DEC + C AG +C N G Y C C +G+R C D + C E+
Sbjct: 5146 QDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINE--CQ---ESS 5200
Query: 373 RCHRARPLQLARPECCCSEGAAW-GRYC-------ERCPAPDSA--------EFMRICQG 416
CH+ + C C G GR C + PD + + +C
Sbjct: 5201 PCHQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPN 5260
Query: 417 GMGRPN--LTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
GM + D+DEC+ C + C NT GS+RC CP GY G C+D +EC
Sbjct: 5261 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECE 5320
Query: 474 LDPRICGNGTCSNTRGGYECQCSPG-FTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
P+ C + CSNT G ++C C PG G ++C ++ + +N A
Sbjct: 5321 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPN--YGTQYSSYNLARF-- 5375
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
Y + E R + + CPEG + S +
Sbjct: 5376 SPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEG------SEASHDT 5429
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+ECE D C C NT GS+ C C G++ + +G C D
Sbjct: 5430 CVDIDECENT-DACQHE-CKNTFGSYQCICPPGYQLTHNGKTCQD 5472
Score = 122 bits (295), Expect = 4e-27
Identities = 70/179 (39%), Positives = 94/179 (52%), Gaps = 16/179 (8%)
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTFR 523
S V++D ++ + S ++G QC GFT C D DECA G C+
Sbjct: 5062 SSVESDYNQIEETLGFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECAAGNP-CSHS 5120
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA---CENVVGSYIC--KCPE 578
CHN G++ C+CP G +AADG C+DIDEC C HA C+N +GSY C +C
Sbjct: 5121 CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTC-HAGQDCDNTIGSYRCVVRCGS 5179
Query: 579 GYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
G+RRTS +C+DINEC+E C C N GSF C C+ G++ G C+D
Sbjct: 5180 GFRRTS----DGLSCQDINECQESSP-CHQR-CFNAIGSFHCGCEPGYQLK--GRKCMD 5230
Score = 97.5 bits (232), Expect = 2e-19
Identities = 48/101 (47%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Query: 759 APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDC--LCRTGYELDEDG 816
A G F C C PGY+ G C DV+EC DQ C NT G Y C LC G E+G
Sbjct: 5209 AIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 5268
Query: 817 ANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRG 855
C D+DEC+ TH C+ QIC NT GSY C C GY +G
Sbjct: 5269 -TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQG 5308
Score = 94.7 bits (225), Expect = 1e-18
Identities = 51/125 (40%), Positives = 68/125 (54%), Gaps = 12/125 (9%)
Query: 746 ADVDECAA---IPGLC--APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCD--QLCH 796
AD DECAA C A G + C C G A G C D+DECA+ C Q C
Sbjct: 5106 ADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCD 5165
Query: 797 NTDGSYDCL--CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
NT GSY C+ C +G+ DG +C+D++EC+ ++ C Q C N GS+ C CE GY+ +
Sbjct: 5166 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 5224
Query: 855 GDACV 859
G C+
Sbjct: 5225 GRKCM 5229
Score = 85.4 bits (202), Expect = 8e-16
Identities = 41/97 (42%), Positives = 48/97 (49%), Gaps = 5/97 (5%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
+C G G CAD DECA P C CHN G+Y C C G + DG C+D+D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 824 ECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD 856
EC HTC Q C NT GSY C C G+ + D
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSD 5186
Score = 85.0 bits (201), Expect = 1e-15
Identities = 48/129 (37%), Positives = 63/129 (48%), Gaps = 17/129 (13%)
Query: 747 DVDECAAIPGLCAP--------GRFRCV--CGPGYRPAGE-VCADVDECAVRPPPC--DQ 793
DV+EC +C P G ++C+ C G A C D+DEC C +Q
Sbjct: 5230 DVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQ 5287
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
+C NT GSY C+C GY G C D++ECE+ C CSNT GS++C C G
Sbjct: 5288 ICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHL 5347
Query: 854 RGD--ACVG 860
GD +C G
Sbjct: 5348 LGDGKSCAG 5356
Score = 83.0 bits (196), Expect = 4e-15
Identities = 43/103 (41%), Positives = 58/103 (56%), Gaps = 7/103 (6%)
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
S TR C G ++ TCVD+DEC E +C C NT GS++C CP GY + +
Sbjct: 5409 SRTRRTIRKTCPEG-SEASHDTCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLTHN 5466
Query: 545 GVHCRDIDECVQEPRVC-PH-ACENVVGSYIC---KCPEGYRR 582
G C+DIDEC+++ C P+ C N+ GSY C CP Y+R
Sbjct: 5467 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 5509
Score = 79.4 bits (187), Expect = 5e-14
Identities = 36/95 (37%), Positives = 51/95 (53%), Gaps = 6/95 (6%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
R C G + + C D+DEC C C NT GSY C+C GY+L +G C+D+D
Sbjct: 5416 RKTCPEGSEASHDTCVDIDECE-NTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDID 5474
Query: 824 EC-ERDTHT-CQQICSNTEGSYEC---SCEDGYEK 853
EC E++ H ++C N GSY+C C Y++
Sbjct: 5475 ECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 5509
Score = 66.5 bits (155), Expect = 4e-10
Identities = 28/65 (43%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 761 GRFRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
G +RCVC GYR G C D++EC P PC C NT GS+ C+C G L DG +
Sbjct: 5294 GSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKS 5353
Query: 819 CRDVD 823
C ++
Sbjct: 5354 CAGLE 5358
Score = 55.6 bits (128), Expect = 7e-07
Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC+ C+ C +T +QC C GY+ + C+D+DEC C C
Sbjct: 5433 IDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCF 5490
Query: 128 NLPGAFEC---RCPPGYRLTPSLDEC 150
N+ G+++C CPP Y+ P C
Sbjct: 5491 NMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Score = 52.8 bits (121), Expect = 5e-06
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 12/89 (13%)
Query: 743 DVFADVDECA---AIPGLCAP--GRFRCVCGPGYRPA--GEVCADVDECAVRPPPC--DQ 793
D D+DEC A C G ++C+C PGY+ G+ C D+DEC + C ++
Sbjct: 5428 DTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNR 5487
Query: 794 LCHNTDGSYDCL---CRTGYELDEDGANC 819
+C N GSY C+ C Y+ D C
Sbjct: 5488 MCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 228 bits (558), Expect = 6e-59
Identities = 146/433 (33%), Positives = 196/433 (45%), Gaps = 36/433 (8%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C G+ D+ C D DEC+ G P C C N G + C CP G + C+D+
Sbjct: 2130 CPSGFTLDSVGPFCADEDECAAGNP-CSH--SCHNAMGTYYCSCPKGLTIAADGRTCQDI 2186
Query: 154 DECG-DQRICDHG-DCRNTIGSYRCECKPGYTLRENV----CRDVDECSRPRPVCRNGTC 207
DEC + C G DC NTIGSYRC + G R C+D++EC P C C
Sbjct: 2187 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RC 2244
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRC-ECAPGYTL 265
N G++ C C+ G++ C+DVNECR+ VCR + C+NT G ++C + P
Sbjct: 2245 FNAIGSFHCGCEPGYQL-KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNGMT 2301
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKE 323
A+ C D+DEC + H C N C NT G Y C C G++ VGR C+D +EC++
Sbjct: 2302 KAENGTCIDIDECKDGTHQCRY--NQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 2359
Query: 324 LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKE---LCYDEWEAGRCHRAR- 378
+P CA +C N G + C CP G C ER Y + R R
Sbjct: 2360 VPKPCA-HQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 2418
Query: 379 ---PLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC-QGGMGRPNLTQDLDECRVRP 434
P Q R + R + + C +G + D+DEC
Sbjct: 2419 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECE-NT 2477
Query: 435 DVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
D C C NT GS++C CP GY L +G +C D DEC CG N C N RG Y+C
Sbjct: 2478 DAC-QHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 2536
Query: 494 ---QCSPGFTQGP 503
C P + + P
Sbjct: 2537 IDTPCPPNYQRDP 2549
Score = 208 bits (508), Expect = 6e-53
Identities = 156/457 (34%), Positives = 206/457 (45%), Gaps = 62/457 (13%)
Query: 177 ECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK-AGPNNDCVDV 233
+C G+TL C D DEC+ P C + +C N G Y C C G A C D+
Sbjct: 2129 QCPSGFTLDSVGPFCADEDECAAGNP-CSH-SCHNAMGTYYCSCPKGLTIAADGRTCQDI 2186
Query: 234 NECREGGMVCRNGR-CRNTVGSFRC--ECAPGYTLTADGRNCRDVDECDELPHPCGRDGN 290
+EC G C G+ C NT+GS+RC C G+ T+DG +C+D++EC E PC +
Sbjct: 2187 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSPC----H 2241
Query: 291 PSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVC--ECPAG 347
C N G + C C G++L GR+C+D +EC++ VC + C+N GGY C CP G
Sbjct: 2242 QRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNG 2299
Query: 348 WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS 407
+ C+D DE + G H+ R Q+ C G Y RC P
Sbjct: 2300 MTKAEN-GTCID------IDECKDG-THQCRYNQI------CEN--TRGSY--RCVCPRG 2341
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
G+GRP D++EC P C +C NT GSF+C CP G L DG SC
Sbjct: 2342 YR-----SQGVGRP--CMDINECEQVPKPC-AHQCSNTPGSFKCICPPGQHLLGDGKSCA 2393
Query: 468 DADEC---ALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
+ S R Y+ Q Q Q +E R S T
Sbjct: 2394 GLERLPNYGTQYSSYNLARFSPVRNNYQPQ------QHYRQYSHLYSSYSEYRNSRT-SL 2446
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
T + R TCP G + D C DIDEC + C H C+N GSY C CP GY+ T
Sbjct: 2447 SRTRRTIRKTCPEGSEASHD--TCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLT- 2502
Query: 585 APQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
+ C+DI+EC EQ C +C N GS+ C
Sbjct: 2503 ---HNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 2536
Score = 197 bits (480), Expect = 2e-49
Identities = 133/425 (31%), Positives = 187/425 (44%), Gaps = 43/425 (10%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC--RCPP 139
+CH+ + C C G C+D+DEC+ GR C C N G++ C RC
Sbjct: 2158 SCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGS 2217
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPR 199
G+R T C+D++EC + C H C N IGS+ C C+PGY L+ C DV+EC +
Sbjct: 2218 GFRRTSDGLSCQDINECQESSPC-HQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQN- 2275
Query: 200 PVCR-NGTCENLPGAYLCH--CDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSF 255
VCR + C+N G Y C C +G N C+D++EC++G CR N C NT GS+
Sbjct: 2276 -VCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSY 2334
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
RC C GY GR C D++EC+++P PC C+NT G ++C C G L+G
Sbjct: 2335 RCVCPRGYRSQGVGRPCMDINECEQVPKPCAH----QCSNTPGSFKCICPPGQHLLG--- 2387
Query: 316 VDRDECKELPYV-CAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC 374
D C L + G + ++N P + Y E+ R
Sbjct: 2388 -DGKSCAGLERLPNYGTQYSSYN--LARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRT 2444
Query: 375 HRARPLQLARPECCCSEGAAWGRY--CERCPAPDSAE---------FMRICQGG---MGR 420
+R + R C A+ + C D+ + + IC G
Sbjct: 2445 SLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHN 2504
Query: 421 PNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC---ECPDGYVLAP-DGL---SCVDAD-E 471
QD+DEC + C R C N GS++C CP Y P G +C D E
Sbjct: 2505 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLE 2564
Query: 472 CALDP 476
CAL P
Sbjct: 2565 CALSP 2569
Score = 166 bits (403), Expect = 3e-40
Identities = 91/234 (38%), Positives = 118/234 (50%), Gaps = 19/234 (8%)
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVD 193
+CP G+ L C D DEC C H C N +G+Y C C G T+ + C+D+D
Sbjct: 2129 QCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 2187
Query: 194 ECSRPRPVCRNGT-CENLPGAYLC--HCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCR 249
EC+ R C G C+N G+Y C C GF+ + C D+NEC+E C RC
Sbjct: 2188 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCF 2245
Query: 250 NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS--CGAG 307
N +GSF C C PGY L GR C DV+EC + + C D + C NT GGY+C C G
Sbjct: 2246 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQ--NVCRPDQH--CKNTRGGYKCIDLCPNG 2299
Query: 308 W-KLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVD 359
K C+D DECK+ + C + C N G Y C CP G+R C+D
Sbjct: 2300 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMD 2353
Score = 156 bits (378), Expect = 4e-37
Identities = 115/323 (35%), Positives = 142/323 (43%), Gaps = 47/323 (14%)
Query: 343 ECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERC 402
+CP+G+ D C DE DE AG C S A G Y C
Sbjct: 2129 QCPSGFTLDSVGPFCADE------DECAAGN------------PCSHSCHNAMGTYYCSC 2170
Query: 403 PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC--ECPDGYVL 459
P + + I G QD+DEC + C G+ C NT GS+RC C G+
Sbjct: 2171 P-----KGLTIAADG----RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRR 2221
Query: 460 APDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS 519
DGLSC D +EC + C + C N G + C C PG+ Q + C+DV+EC +
Sbjct: 2222 TSDGLSCQDINECQ-ESSPC-HQRCFNAIGSFHCGCEPGY-QLKGRKCMDVNECRQNVCR 2278
Query: 520 CTFRCHNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPH--ACENVVGSYICK 575
C NT G ++C CP G A +G C DIDEC C + CEN GSY C
Sbjct: 2279 PDQHCKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCV 2337
Query: 576 CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
CP GYR Q C DINECE+ C+ C NT GSF C C G DG C
Sbjct: 2338 CPRGYRS----QGVGRPCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDGKSC 2392
Query: 636 --IDR--RTGTCYRSLVSGRCEP 654
++R GT Y S R P
Sbjct: 2393 AGLERLPNYGTQYSSYNLARFSP 2415
Score = 151 bits (365), Expect = 1e-35
Identities = 90/255 (35%), Positives = 124/255 (48%), Gaps = 20/255 (7%)
Query: 35 CEACPPRGSPAHTAL----CGEKPGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTG 89
C A P H A+ C G I + IDEC + C G C +T
Sbjct: 2149 CAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGS 2208
Query: 90 FQC--GCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
++C C G+ + C+D++EC P C +C N G+F C C PGY+L
Sbjct: 2209 YRCVVRCGSGFRRTSDGLSCQDINECQESSP-CH--QRCFNAIGSFHCGCEPGYQLKGR- 2264
Query: 148 DECEDVDECGDQRICDHGD-CRNTIGSYRCE--CKPGYTLREN-VCRDVDECSRPRPVCR 203
+C DV+EC Q +C C+NT G Y+C C G T EN C D+DEC CR
Sbjct: 2265 -KCMDVNECR-QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCR 2322
Query: 204 -NGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAP 261
N CEN G+Y C C G+++ G C+D+NEC + C + +C NT GSF+C C P
Sbjct: 2323 YNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPP 2381
Query: 262 GYTLTADGRNCRDVD 276
G L DG++C ++
Sbjct: 2382 GQHLLGDGKSCAGLE 2396
Score = 136 bits (328), Expect = 4e-31
Identities = 119/405 (29%), Positives = 164/405 (40%), Gaps = 48/405 (11%)
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRC 315
+C G+TL + G C D DEC +PC SC N G Y CSC G + GR C
Sbjct: 2129 QCPSGFTLDSVGPFCADEDEC-AAGNPCSH----SCHNAMGTYYCSCPKGLTIAADGRTC 2183
Query: 316 VDRDECKELPYVC-AGGECRNFNGGYVC--ECPAGWRFDKTAAVCVDERKELCYDEWEAG 372
D DEC + C AG +C N G Y C C +G+R C D + C E+
Sbjct: 2184 QDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINE--CQ---ESS 2238
Query: 373 RCHRARPLQLARPECCCSEGAAW-GRYC-------ERCPAPDSA--------EFMRICQG 416
CH+ + C C G GR C + PD + + +C
Sbjct: 2239 PCHQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPN 2298
Query: 417 GMGRPN--LTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
GM + D+DEC+ C + C NT GS+RC CP GY G C+D +EC
Sbjct: 2299 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECE 2358
Query: 474 LDPRICGNGTCSNTRGGYECQCSPG-FTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
P+ C + CSNT G ++C C PG G ++C ++ + +N A
Sbjct: 2359 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPN--YGTQYSSYNLARF-- 2413
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
Y + E R + + CPEG + S +
Sbjct: 2414 SPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEG------SEASHDT 2467
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+ECE D C C NT GS+ C C G++ + +G C D
Sbjct: 2468 CVDIDECENT-DACQHE-CKNTFGSYQCICPPGYQLTHNGKTCQD 2510
Score = 122 bits (295), Expect = 4e-27
Identities = 70/179 (39%), Positives = 94/179 (52%), Gaps = 16/179 (8%)
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTFR 523
S V++D ++ + S ++G QC GFT C D DECA G C+
Sbjct: 2100 SSVESDYNQIEETLGFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECAAGNP-CSHS 2158
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA---CENVVGSYIC--KCPE 578
CHN G++ C+CP G +AADG C+DIDEC C HA C+N +GSY C +C
Sbjct: 2159 CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTC-HAGQDCDNTIGSYRCVVRCGS 2217
Query: 579 GYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
G+RRTS +C+DINEC+E C C N GSF C C+ G++ G C+D
Sbjct: 2218 GFRRTS----DGLSCQDINECQESSP-CHQR-CFNAIGSFHCGCEPGYQLK--GRKCMD 2268
Score = 97.5 bits (232), Expect = 2e-19
Identities = 48/101 (47%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Query: 759 APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDC--LCRTGYELDEDG 816
A G F C C PGY+ G C DV+EC DQ C NT G Y C LC G E+G
Sbjct: 2247 AIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 2306
Query: 817 ANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRG 855
C D+DEC+ TH C+ QIC NT GSY C C GY +G
Sbjct: 2307 -TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQG 2346
Score = 94.7 bits (225), Expect = 1e-18
Identities = 51/125 (40%), Positives = 68/125 (54%), Gaps = 12/125 (9%)
Query: 746 ADVDECAA---IPGLC--APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCD--QLCH 796
AD DECAA C A G + C C G A G C D+DECA+ C Q C
Sbjct: 2144 ADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCD 2203
Query: 797 NTDGSYDCL--CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
NT GSY C+ C +G+ DG +C+D++EC+ ++ C Q C N GS+ C CE GY+ +
Sbjct: 2204 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 2262
Query: 855 GDACV 859
G C+
Sbjct: 2263 GRKCM 2267
Score = 85.4 bits (202), Expect = 8e-16
Identities = 41/97 (42%), Positives = 48/97 (49%), Gaps = 5/97 (5%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
+C G G CAD DECA P C CHN G+Y C C G + DG C+D+D
Sbjct: 2129 QCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDID 2187
Query: 824 ECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD 856
EC HTC Q C NT GSY C C G+ + D
Sbjct: 2188 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSD 2224
Score = 85.0 bits (201), Expect = 1e-15
Identities = 48/129 (37%), Positives = 63/129 (48%), Gaps = 17/129 (13%)
Query: 747 DVDECAAIPGLCAP--------GRFRCV--CGPGYRPAGE-VCADVDECAVRPPPC--DQ 793
DV+EC +C P G ++C+ C G A C D+DEC C +Q
Sbjct: 2268 DVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQ 2325
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
+C NT GSY C+C GY G C D++ECE+ C CSNT GS++C C G
Sbjct: 2326 ICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHL 2385
Query: 854 RGD--ACVG 860
GD +C G
Sbjct: 2386 LGDGKSCAG 2394
Score = 83.0 bits (196), Expect = 4e-15
Identities = 43/103 (41%), Positives = 58/103 (56%), Gaps = 7/103 (6%)
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
S TR C G ++ TCVD+DEC E +C C NT GS++C CP GY + +
Sbjct: 2447 SRTRRTIRKTCPEG-SEASHDTCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLTHN 2504
Query: 545 GVHCRDIDECVQEPRVC-PH-ACENVVGSYIC---KCPEGYRR 582
G C+DIDEC+++ C P+ C N+ GSY C CP Y+R
Sbjct: 2505 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 2547
Score = 79.4 bits (187), Expect = 5e-14
Identities = 36/95 (37%), Positives = 51/95 (53%), Gaps = 6/95 (6%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
R C G + + C D+DEC C C NT GSY C+C GY+L +G C+D+D
Sbjct: 2454 RKTCPEGSEASHDTCVDIDECE-NTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDID 2512
Query: 824 EC-ERDTHT-CQQICSNTEGSYEC---SCEDGYEK 853
EC E++ H ++C N GSY+C C Y++
Sbjct: 2513 ECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 2547
Score = 66.5 bits (155), Expect = 4e-10
Identities = 28/65 (43%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 761 GRFRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
G +RCVC GYR G C D++EC P PC C NT GS+ C+C G L DG +
Sbjct: 2332 GSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKS 2391
Query: 819 CRDVD 823
C ++
Sbjct: 2392 CAGLE 2396
Score = 55.6 bits (128), Expect = 7e-07
Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC+ C+ C +T +QC C GY+ + C+D+DEC C C
Sbjct: 2471 IDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCF 2528
Query: 128 NLPGAFEC---RCPPGYRLTPSLDEC 150
N+ G+++C CPP Y+ P C
Sbjct: 2529 NMRGSYQCIDTPCPPNYQRDPVSGFC 2554
Score = 52.8 bits (121), Expect = 5e-06
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 12/89 (13%)
Query: 743 DVFADVDECA---AIPGLCAP--GRFRCVCGPGYRPA--GEVCADVDECAVRPPPC--DQ 793
D D+DEC A C G ++C+C PGY+ G+ C D+DEC + C ++
Sbjct: 2466 DTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNR 2525
Query: 794 LCHNTDGSYDCL---CRTGYELDEDGANC 819
+C N GSY C+ C Y+ D C
Sbjct: 2526 MCFNMRGSYQCIDTPCPPNYQRDPVSGFC 2554
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 228 bits (557), Expect = 7e-59
Identities = 146/433 (33%), Positives = 195/433 (45%), Gaps = 36/433 (8%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C G+ D+ C D DEC+ G P C C N G + C CP G + C+D+
Sbjct: 5093 CPSGFTLDSVGPFCADEDECAAGNP-CSH--SCHNAMGTYYCSCPKGLTIAADGRTCQDI 5149
Query: 154 DECG-DQRICDHG-DCRNTIGSYRCECKPGYTLRENV----CRDVDECSRPRPVCRNGTC 207
DEC + C G DC NTIGSYRC + G R C+D++EC P C C
Sbjct: 5150 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RC 5207
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRC-ECAPGYTL 265
N G++ C C+ G++ C+DVNECR+ VCR + C+NT G ++C + P
Sbjct: 5208 FNAIGSFHCGCEPGYQL-KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNGMT 5264
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKE 323
A+ C D+DEC + H C N C NT Y C C G++ VGR C+D DEC++
Sbjct: 5265 KAENGTCIDIDECKDGTHQCRY--NQICENTRSSYRCVCPRGYRSQGVGRPCMDIDECEQ 5322
Query: 324 LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-ERKE---LCYDEWEAGRCHRAR- 378
+P CA +C N G + C CP G C ER Y + R R
Sbjct: 5323 VPKPCA-HQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 5381
Query: 379 ---PLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC-QGGMGRPNLTQDLDECRVRP 434
P Q R + R + + C +G + D+DEC
Sbjct: 5382 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECE-NT 5440
Query: 435 DVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
D C C NT GS++C CP GY L +G +C D DEC CG N C N RG Y+C
Sbjct: 5441 DAC-QHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5499
Query: 494 ---QCSPGFTQGP 503
C P + + P
Sbjct: 5500 IDTPCPPNYQRDP 5512
Score = 209 bits (511), Expect = 3e-53
Identities = 156/457 (34%), Positives = 205/457 (44%), Gaps = 62/457 (13%)
Query: 177 ECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK-AGPNNDCVDV 233
+C G+TL C D DEC+ P C + +C N G Y C C G A C D+
Sbjct: 5092 QCPSGFTLDSVGPFCADEDECAAGNP-CSH-SCHNAMGTYYCSCPKGLTIAADGRTCQDI 5149
Query: 234 NECREGGMVCRNGR-CRNTVGSFRC--ECAPGYTLTADGRNCRDVDECDELPHPCGRDGN 290
+EC G C G+ C NT+GS+RC C G+ T+DG +C+D++EC E PC +
Sbjct: 5150 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSPC----H 5204
Query: 291 PSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVC--ECPAG 347
C N G + C C G++L GR+C+D +EC++ VC + C+N GGY C CP G
Sbjct: 5205 QRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNG 5262
Query: 348 WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS 407
+ C+D DE + G H+ R Q+ C R RC P
Sbjct: 5263 MTKAEN-GTCID------IDECKDG-THQCRYNQI------CEN----TRSSYRCVCPRG 5304
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
G+GRP D+DEC P C +C NT GSF+C CP G L DG SC
Sbjct: 5305 YR-----SQGVGRP--CMDIDECEQVPKPC-AHQCSNTPGSFKCICPPGQHLLGDGKSCA 5356
Query: 468 DADEC---ALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
+ S R Y+ Q Q Q +E R S T
Sbjct: 5357 GLERLPNYGTQYSSYNLARFSPVRNNYQPQ------QHYRQYSHLYSSYSEYRNSRT-SL 5409
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
T + R TCP G + D C DIDEC + C H C+N GSY C CP GY+ T
Sbjct: 5410 SRTRRTIRKTCPEGSEASHD--TCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLT- 5465
Query: 585 APQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
+ C+DI+EC EQ C +C N GS+ C
Sbjct: 5466 ---HNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5499
Score = 196 bits (479), Expect = 2e-49
Identities = 133/425 (31%), Positives = 186/425 (43%), Gaps = 43/425 (10%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC--RCPP 139
+CH+ + C C G C+D+DEC+ GR C C N G++ C RC
Sbjct: 5121 SCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGS 5180
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPR 199
G+R T C+D++EC + C H C N IGS+ C C+PGY L+ C DV+EC +
Sbjct: 5181 GFRRTSDGLSCQDINECQESSPC-HQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQN- 5238
Query: 200 PVCR-NGTCENLPGAYLCH--CDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSF 255
VCR + C+N G Y C C +G N C+D++EC++G CR N C NT S+
Sbjct: 5239 -VCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRSSY 5297
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
RC C GY GR C D+DEC+++P PC C+NT G ++C C G L+G
Sbjct: 5298 RCVCPRGYRSQGVGRPCMDIDECEQVPKPCAH----QCSNTPGSFKCICPPGQHLLG--- 5350
Query: 316 VDRDECKELPYV-CAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC 374
D C L + G + ++N P + Y E+ R
Sbjct: 5351 -DGKSCAGLERLPNYGTQYSSYN--LARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRT 5407
Query: 375 HRARPLQLARPECCCSEGAAWGRY--CERCPAPDSAE---------FMRICQGG---MGR 420
+R + R C A+ + C D+ + + IC G
Sbjct: 5408 SLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHN 5467
Query: 421 PNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC---ECPDGYVLAP-DGL---SCVDAD-E 471
QD+DEC + C R C N GS++C CP Y P G +C D E
Sbjct: 5468 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLE 5527
Query: 472 CALDP 476
CAL P
Sbjct: 5528 CALSP 5532
Score = 163 bits (397), Expect = 2e-39
Identities = 90/234 (38%), Positives = 117/234 (50%), Gaps = 19/234 (8%)
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVD 193
+CP G+ L C D DEC C H C N +G+Y C C G T+ + C+D+D
Sbjct: 5092 QCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 5150
Query: 194 ECSRPRPVCRNGT-CENLPGAYLC--HCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCR 249
EC+ R C G C+N G+Y C C GF+ + C D+NEC+E C RC
Sbjct: 5151 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCF 5208
Query: 250 NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS--CGAG 307
N +GSF C C PGY L GR C DV+EC + + C D + C NT GGY+C C G
Sbjct: 5209 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQ--NVCRPDQH--CKNTRGGYKCIDLCPNG 5262
Query: 308 W-KLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVD 359
K C+D DECK+ + C + C N Y C CP G+R C+D
Sbjct: 5263 MTKAENGTCIDIDECKDGTHQCRYNQICENTRSSYRCVCPRGYRSQGVGRPCMD 5316
Score = 151 bits (367), Expect = 8e-36
Identities = 113/323 (34%), Positives = 141/323 (43%), Gaps = 47/323 (14%)
Query: 343 ECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERC 402
+CP+G+ D C DE DE AG C S A G Y C
Sbjct: 5092 QCPSGFTLDSVGPFCADE------DECAAGN------------PCSHSCHNAMGTYYCSC 5133
Query: 403 PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC--ECPDGYVL 459
P + + I G QD+DEC + C G+ C NT GS+RC C G+
Sbjct: 5134 P-----KGLTIAADG----RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRR 5184
Query: 460 APDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS 519
DGLSC D +EC + C + C N G + C C PG+ Q + C+DV+EC +
Sbjct: 5185 TSDGLSCQDINECQ-ESSPC-HQRCFNAIGSFHCGCEPGY-QLKGRKCMDVNECRQNVCR 5241
Query: 520 CTFRCHNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPH--ACENVVGSYICK 575
C NT G ++C CP G A +G C DIDEC C + CEN SY C
Sbjct: 5242 PDQHCKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRSSYRCV 5300
Query: 576 CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
CP GYR Q C DI+ECE+ C+ C NT GSF C C G DG C
Sbjct: 5301 CPRGYRS----QGVGRPCMDIDECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDGKSC 5355
Query: 636 --IDR--RTGTCYRSLVSGRCEP 654
++R GT Y S R P
Sbjct: 5356 AGLERLPNYGTQYSSYNLARFSP 5378
Score = 146 bits (354), Expect = 3e-34
Identities = 88/255 (34%), Positives = 123/255 (48%), Gaps = 20/255 (7%)
Query: 35 CEACPPRGSPAHTAL----CGEKPGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTG 89
C A P H A+ C G I + IDEC + C G C +T
Sbjct: 5112 CAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGS 5171
Query: 90 FQC--GCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
++C C G+ + C+D++EC P C +C N G+F C C PGY+L
Sbjct: 5172 YRCVVRCGSGFRRTSDGLSCQDINECQESSP-CH--QRCFNAIGSFHCGCEPGYQLKGR- 5227
Query: 148 DECEDVDECGDQRICDHGD-CRNTIGSYRCE--CKPGYTLREN-VCRDVDECSRPRPVCR 203
+C DV+EC Q +C C+NT G Y+C C G T EN C D+DEC CR
Sbjct: 5228 -KCMDVNECR-QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCR 5285
Query: 204 -NGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAP 261
N CEN +Y C C G+++ G C+D++EC + C + +C NT GSF+C C P
Sbjct: 5286 YNQICENTRSSYRCVCPRGYRSQGVGRPCMDIDECEQVPKPCAH-QCSNTPGSFKCICPP 5344
Query: 262 GYTLTADGRNCRDVD 276
G L DG++C ++
Sbjct: 5345 GQHLLGDGKSCAGLE 5359
Score = 135 bits (327), Expect = 5e-31
Identities = 119/405 (29%), Positives = 163/405 (40%), Gaps = 48/405 (11%)
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRC 315
+C G+TL + G C D DEC +PC SC N G Y CSC G + GR C
Sbjct: 5092 QCPSGFTLDSVGPFCADEDEC-AAGNPCSH----SCHNAMGTYYCSCPKGLTIAADGRTC 5146
Query: 316 VDRDECKELPYVC-AGGECRNFNGGYVC--ECPAGWRFDKTAAVCVDERKELCYDEWEAG 372
D DEC + C AG +C N G Y C C +G+R C D + C E+
Sbjct: 5147 QDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINE--CQ---ESS 5201
Query: 373 RCHRARPLQLARPECCCSEGAAW-GRYC-------ERCPAPDSA--------EFMRICQG 416
CH+ + C C G GR C + PD + + +C
Sbjct: 5202 PCHQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPN 5261
Query: 417 GMGRPN--LTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
GM + D+DEC+ C + C NT S+RC CP GY G C+D DEC
Sbjct: 5262 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRSSYRCVCPRGYRSQGVGRPCMDIDECE 5321
Query: 474 LDPRICGNGTCSNTRGGYECQCSPG-FTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
P+ C + CSNT G ++C C PG G ++C ++ + +N A
Sbjct: 5322 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPN--YGTQYSSYNLARF-- 5376
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
Y + E R + + CPEG + S +
Sbjct: 5377 SPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEG------SEASHDT 5430
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+ECE D C C NT GS+ C C G++ + +G C D
Sbjct: 5431 CVDIDECENT-DACQHE-CKNTFGSYQCICPPGYQLTHNGKTCQD 5473
Score = 122 bits (295), Expect = 4e-27
Identities = 70/179 (39%), Positives = 94/179 (52%), Gaps = 16/179 (8%)
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTFR 523
S V++D ++ + S ++G QC GFT C D DECA G C+
Sbjct: 5063 SSVESDYNQIEETLGFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECAAGNP-CSHS 5121
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA---CENVVGSYIC--KCPE 578
CHN G++ C+CP G +AADG C+DIDEC C HA C+N +GSY C +C
Sbjct: 5122 CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTC-HAGQDCDNTIGSYRCVVRCGS 5180
Query: 579 GYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
G+RRTS +C+DINEC+E C C N GSF C C+ G++ G C+D
Sbjct: 5181 GFRRTS----DGLSCQDINECQESSP-CHQR-CFNAIGSFHCGCEPGYQLK--GRKCMD 5231
Score = 95.1 bits (226), Expect = 9e-19
Identities = 47/101 (46%), Positives = 54/101 (53%), Gaps = 5/101 (4%)
Query: 759 APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDC--LCRTGYELDEDG 816
A G F C C PGY+ G C DV+EC DQ C NT G Y C LC G E+G
Sbjct: 5210 AIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 5269
Query: 817 ANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRG 855
C D+DEC+ TH C+ QIC NT SY C C GY +G
Sbjct: 5270 -TCIDIDECKDGTHQCRYNQICENTRSSYRCVCPRGYRSQG 5309
Score = 94.7 bits (225), Expect = 1e-18
Identities = 51/125 (40%), Positives = 68/125 (54%), Gaps = 12/125 (9%)
Query: 746 ADVDECAA---IPGLC--APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCD--QLCH 796
AD DECAA C A G + C C G A G C D+DECA+ C Q C
Sbjct: 5107 ADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCD 5166
Query: 797 NTDGSYDCL--CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
NT GSY C+ C +G+ DG +C+D++EC+ ++ C Q C N GS+ C CE GY+ +
Sbjct: 5167 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 5225
Query: 855 GDACV 859
G C+
Sbjct: 5226 GRKCM 5230
Score = 85.4 bits (202), Expect = 8e-16
Identities = 41/97 (42%), Positives = 48/97 (49%), Gaps = 5/97 (5%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
+C G G CAD DECA P C CHN G+Y C C G + DG C+D+D
Sbjct: 5092 QCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDID 5150
Query: 824 ECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD 856
EC HTC Q C NT GSY C C G+ + D
Sbjct: 5151 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSD 5187
Score = 84.6 bits (200), Expect = 1e-15
Identities = 48/129 (37%), Positives = 62/129 (48%), Gaps = 17/129 (13%)
Query: 747 DVDECAAIPGLCAP--------GRFRCV--CGPGYRPAGE-VCADVDECAVRPPPC--DQ 793
DV+EC +C P G ++C+ C G A C D+DEC C +Q
Sbjct: 5231 DVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQ 5288
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
+C NT SY C+C GY G C D+DECE+ C CSNT GS++C C G
Sbjct: 5289 ICENTRSSYRCVCPRGYRSQGVGRPCMDIDECEQVPKPCAHQCSNTPGSFKCICPPGQHL 5348
Query: 854 RGD--ACVG 860
GD +C G
Sbjct: 5349 LGDGKSCAG 5357
Score = 83.0 bits (196), Expect = 4e-15
Identities = 43/103 (41%), Positives = 58/103 (56%), Gaps = 7/103 (6%)
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
S TR C G ++ TCVD+DEC E +C C NT GS++C CP GY + +
Sbjct: 5410 SRTRRTIRKTCPEG-SEASHDTCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLTHN 5467
Query: 545 GVHCRDIDECVQEPRVC-PH-ACENVVGSYIC---KCPEGYRR 582
G C+DIDEC+++ C P+ C N+ GSY C CP Y+R
Sbjct: 5468 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 5510
Score = 79.4 bits (187), Expect = 5e-14
Identities = 36/95 (37%), Positives = 51/95 (53%), Gaps = 6/95 (6%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
R C G + + C D+DEC C C NT GSY C+C GY+L +G C+D+D
Sbjct: 5417 RKTCPEGSEASHDTCVDIDECE-NTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDID 5475
Query: 824 EC-ERDTHT-CQQICSNTEGSYEC---SCEDGYEK 853
EC E++ H ++C N GSY+C C Y++
Sbjct: 5476 ECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 5510
Score = 66.5 bits (155), Expect = 4e-10
Identities = 28/63 (44%), Positives = 35/63 (55%), Gaps = 2/63 (3%)
Query: 763 FRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
+RCVC GYR G C D+DEC P PC C NT GS+ C+C G L DG +C
Sbjct: 5297 YRCVCPRGYRSQGVGRPCMDIDECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCA 5356
Query: 821 DVD 823
++
Sbjct: 5357 GLE 5359
Score = 55.6 bits (128), Expect = 7e-07
Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC+ C+ C +T +QC C GY+ + C+D+DEC C C
Sbjct: 5434 IDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCF 5491
Query: 128 NLPGAFEC---RCPPGYRLTPSLDEC 150
N+ G+++C CPP Y+ P C
Sbjct: 5492 NMRGSYQCIDTPCPPNYQRDPVSGFC 5517
Score = 52.8 bits (121), Expect = 5e-06
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 12/89 (13%)
Query: 743 DVFADVDECA---AIPGLCAP--GRFRCVCGPGYRPA--GEVCADVDECAVRPPPC--DQ 793
D D+DEC A C G ++C+C PGY+ G+ C D+DEC + C ++
Sbjct: 5429 DTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNR 5488
Query: 794 LCHNTDGSYDCL---CRTGYELDEDGANC 819
+C N GSY C+ C Y+ D C
Sbjct: 5489 MCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5517
>BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein.
Length = 1235
Score = 225 bits (551), Expect = 4e-58
Identities = 187/616 (30%), Positives = 270/616 (43%), Gaps = 92/616 (14%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQC 126
I+EC P + G C D FQC C G+ T +C+ D+D+CS PC A+C
Sbjct: 495 INECQSNPCV-NNGQCVDKVNRFQCLCPPGF----TGPVCQIDIDDCS--STPCLNGAKC 547
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
++ P +EC+C G+ T L E E++D C D C HG C++ I SY C C PGY
Sbjct: 548 IDHPNGYECQCATGF--TGVLCE-ENIDNC-DPDPCHHGQCQDGIDSYTCICNPGYM--G 601
Query: 187 NVCRD-VDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN 245
+C D +DEC P +G C +L Y C+C G +G N + ++ ++C C +
Sbjct: 602 AICSDQIDECYSS-PCLNDGRCIDLVNGYQCNCQPG-TSGVNCE-INFDDCASNP--CIH 656
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
G C + + + C C+PG+T G+ C D+DEC +PC R G +C N G+ C C
Sbjct: 657 GICMDGINRYSCVCSPGFT----GQRCNIDIDECAS--NPC-RKG-ATCINGVNGFRCIC 708
Query: 305 GAGWKLVGRRCVDR-DECKELPYVCAGGECRNFNGGYVCECPAGW-----RFDKTAAVCV 358
G C + +EC P C G C GY C C AGW DK +
Sbjct: 709 PEGPHHPS--CYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSN 764
Query: 359 D-ERKELCYDEWEAGRC-----HRARPLQLARPEC----CCSEGAAW---GRYCERCPAP 405
+ C + RC + Q+ EC C ++G + Y C P
Sbjct: 765 PCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLP 824
Query: 406 DSAEFMRICQGGMG--RPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDG 463
+ + CQ + PN ++ C+ P+ S+ C C G+ G
Sbjct: 825 YTG---KNCQTVLAPCSPNPCENAAVCKESPNF----------ESYTCLCAPGW----QG 867
Query: 464 LSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF 522
C +D DEC P + +G C NT+G Y C+C PGF+ G D D+D+C
Sbjct: 868 QRCTIDIDECISKPCM-NHGLCHNTQGSYMCECPPGFS-GMDCE-EDIDDCLANPCQNGG 924
Query: 523 RCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRR 582
C + +F C C G+ + D++EC+ EP C + V SY CKC G+
Sbjct: 925 SCMDGVNTFSCLCLPGFT---GDKYQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF-- 979
Query: 583 TSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPS---EDGTDCIDR- 638
D + +INEC E +GG C++ SF C C GF S + +C
Sbjct: 980 -----DGVHCENNINECTE-SSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHP 1033
Query: 639 --RTGTCYRSLVSGRC 652
GTC L + RC
Sbjct: 1034 CLNEGTCVDGLGTYRC 1049
Score = 221 bits (541), Expect = 6e-57
Identities = 179/583 (30%), Positives = 246/583 (42%), Gaps = 72/583 (12%)
Query: 92 CGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLP-GAFECRCPPGYRLTPSLDEC 150
C C G+ ++ + C RP C C L +EC C G+ + EC
Sbjct: 90 CRCASGFTGEDCQYSTSH--PCFVSRP-CLNGGTCHMLSRDTYECTCQVGF----TGKEC 142
Query: 151 EDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGTCEN 209
+ D C + C + C+C G+T ++ C DV+EC P GTC N
Sbjct: 143 QWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQK--CETDVNECDIPGHCQHGGTCLN 200
Query: 210 LPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVG-SFRCECAPGYTLTAD 268
LPG+Y C C GF G D + V C V G CR T +F C C PG+ +
Sbjct: 201 LPGSYQCQCPQGF-TGQYCDSLYV-PCAPSPCV-NGGTCRQTGDFTFECNCLPGF----E 253
Query: 269 GRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV-DRDECKELPY 326
G C R++D+C H C G C + Y C C W G+ C D DEC P
Sbjct: 254 GSTCERNIDDCPN--HRCQNGG--VCVDGVNTYNCRCPPQW--TGQFCTEDVDECLLQPN 307
Query: 327 VCA-GGECRNFNGGYVCECPAGWRFDKTA------AVCVDERKELCYDEWEAGRC---HR 376
C GG C N NGGY C C GW D + A C D + C
Sbjct: 308 ACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEG 367
Query: 377 ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRV-RPD 435
L + C S G C+ P + +++ C G + T+D+DEC + +
Sbjct: 368 KAGLLCHLDDACISNPCHKGALCDTNPL--NGQYICTCPQGYKGADCTEDVDECAMANSN 425
Query: 436 VCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGN-GTCSNTRGGYE 492
C G+CVNTDG+F CEC GY G C +D +EC DP C N TC + GG+
Sbjct: 426 PCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDP--CQNDATCLDKIGGFT 479
Query: 493 CQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DI 551
C C PGF +G ++++EC +C + F+C CP G+ G C+ DI
Sbjct: 480 CLCMPGF-KGV-HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFT----GPVCQIDI 533
Query: 552 DECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVC 611
D+C P + C + Y C+C G+ E+I+ C+ D C G C
Sbjct: 534 DDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCE-------ENIDNCD--PDPCHHGQC 584
Query: 612 INTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS--LVSGRC 652
+ S+ C C+ G+ G C D + CY S L GRC
Sbjct: 585 QDGIDSYTCICNPGYM----GAICSD-QIDECYSSPCLNDGRC 622
Score = 221 bits (539), Expect = 1e-56
Identities = 201/672 (29%), Positives = 286/672 (42%), Gaps = 96/672 (14%)
Query: 21 YLCCCSVGHAWGAPC---EACPPRGSPAHT-ALCGEKP--GEYINPVTNE------TKPI 68
+ C C G A G C +AC +P H ALC P G+YI T+ +
Sbjct: 360 FSCMCPEGKA-GLLCHLDDACI--SNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDV 416
Query: 69 DECDIM-PQLCK-PGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
DEC + C+ G C +T F C C GY D++EC PC+ A C
Sbjct: 417 DECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE---MDINECH--SDPCQNDATC 471
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
++ G F C C PG++ CE +++EC ++G C + + ++C C PG+T
Sbjct: 472 LDKIGGFTCLCMPGFKGV----HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFT-- 525
Query: 186 ENVCR-DVDECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC 243
VC+ D+D+CS C NG C + P Y C C GF + +D C C
Sbjct: 526 GPVCQIDIDDCSSTP--CLNGAKCIDHPNGYECQCATGFTGVLCEENID--NCDPDP--C 579
Query: 244 RNGRCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGGYEC 302
+G+C++ + S+ C C PGY G C D +DEC PC DG C + GY+C
Sbjct: 580 HHGQCQDGIDSYTCICNPGYM----GAICSDQIDEC--YSSPCLNDGR--CIDLVNGYQC 631
Query: 303 SCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE- 360
+C G G C ++ D+C P C G C + Y C C G+ + + +DE
Sbjct: 632 NCQPGTS--GVNCEINFDDCASNP--CIHGICMDGINRYSCVCSPGFTGQR-CNIDIDEC 686
Query: 361 -----RK-ELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYC--ERCPAPDSAEFMR 412
RK C + RC P P C C C S +
Sbjct: 687 ASNPCRKGATCINGVNGFRC--ICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSG-YKC 743
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDAD 470
+C G N D +EC P C GG C N +RC C G+ G +C V+ D
Sbjct: 744 LCDAGWVGINCEVDKNECLSNP--CQNGGTCDNLVNGYRCTCKKGF----KGYNCQVNID 797
Query: 471 ECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAG- 529
ECA +P + GTC + GY C C +T QT + C+ C +
Sbjct: 798 ECASNPCL-NQGTCFDDISGYTCHCVLPYTGKNCQTVLA--PCSPNPCENAAVCKESPNF 854
Query: 530 -SFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQ 587
S+ C C G+ G C DIDEC+ +P + C N GSY+C+CP G+ +
Sbjct: 855 ESYTCLCAPGW----QGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGF----SGM 906
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTD---CID---RRTG 641
D E EDI++C +GG C++ +F C C GF + TD C+ + G
Sbjct: 907 DCE---EDIDDC-LANPCQNGGSCMDGVNTFSCLCLPGFTGDKYQTDMNECLSEPCKNGG 962
Query: 642 TCYRSLVSGRCE 653
TC + S C+
Sbjct: 963 TCSDYVNSYTCK 974
Score = 219 bits (535), Expect = 3e-56
Identities = 240/887 (27%), Positives = 340/887 (38%), Gaps = 125/887 (14%)
Query: 20 KYLCCCSVGHAWGAPCEA----CPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMP 75
++ C C G G CE C G H C PG Y CD +
Sbjct: 165 QFSCKCLTGFT-GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTG-QYCDSLY 222
Query: 76 QLCKP------GTCHDTPT-GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
C P GTC T F+C C G+E R++D+C R C+ CV+
Sbjct: 223 VPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCE---RNIDDCPNHR--CQNGGVCVD 277
Query: 129 LPGAFECRCPPGYRLTPSLDEC-EDVDECGDQ-RICDHGD-CRNTIGSYRCECKPGYTLR 185
+ CRCPP + + C EDVDEC Q C +G C N G Y C C G++
Sbjct: 278 GVNTYNCRCPPQW----TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWS-G 332
Query: 186 ENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGP----NNDCVDVNECREGG 240
++ ++D+C+ C G TC + ++ C C +G KAG ++ C+ N C +G
Sbjct: 333 DDCSENIDDCAFAS--CTPGSTCIDRVASFSCMCPEG-KAGLLCHLDDACIS-NPCHKGA 388
Query: 241 MVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDEL-PHPCGRDGNPSCTNTNG 298
+ N G + C C GY G +C DVDEC +PC G C NT+G
Sbjct: 389 LCDTNP----LNGQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGK--CVNTDG 438
Query: 299 GYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRFDKTAAV 356
+ C C G+ G RC +D +EC P C C + GG+ C C G++
Sbjct: 439 AFHCECLKGY--AGPRCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFKGVHCELE 494
Query: 357 CVDERKELCYDEWEA----GRCHRARPLQLARPEC------CCSEGAAWGRYCERCPAPD 406
+ + C + + R P P C C S G C P+
Sbjct: 495 INECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKC--IDHPN 552
Query: 407 SAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
E C G +++D C PD C G+C + S+ C C GY+ G C
Sbjct: 553 GYECQ--CATGFTGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYM----GAIC 604
Query: 467 VDA-DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
D DEC P + +G C + GY+C C PG T G + ++ D+CA C
Sbjct: 605 SDQIDECYSSPCL-NDGRCIDLVNGYQCNCQPG-TSGVNCE-INFDDCASNPCIHGI-CM 660
Query: 526 NTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
+ + C C G+ G C DIDEC P C N V + C CPEG S
Sbjct: 661 DGINRYSCVCSPGFT----GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPS 716
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF---EPSEDGTDCID---R 638
+NEC C G C + C CDAG+ D +C+ +
Sbjct: 717 C-------YSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQ 767
Query: 639 RTGTCYRSLVSG-RCEPEXXXXXXXXXXXXXXXXXX-----XXXXGHVTKAQCCCTLGAA 692
GTC +LV+G RC + ++ C C L
Sbjct: 768 NGGTC-DNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYT 826
Query: 693 WGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECA 752
G C+ AP SP + +P D+DEC
Sbjct: 827 -GKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTI-------DIDECI 878
Query: 753 AIP----GLC--APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCL 805
+ P GLC G + C C PG+ +G C D+D+C P C + ++ CL
Sbjct: 879 SKPCMNHGLCHNTQGSYMCECPPGF--SGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCL 936
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
C G+ D+ D++EC + CS+ SY C C+ G++
Sbjct: 937 CLPGFTGDKYQT---DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD 980
Score = 210 bits (512), Expect = 2e-53
Identities = 175/587 (29%), Positives = 252/587 (42%), Gaps = 92/587 (15%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD-VDECSWGRPPCRGMAQC 126
ID CD P C G C D + C C+ GY +C D +DEC PC +C
Sbjct: 571 IDNCD--PDPCHHGQCQDGIDSYTCICNPGY----MGAICSDQIDECY--SSPCLNDGRC 622
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYT-L 184
++L ++C C PG T ++ CE + D+C C HG C + I Y C C PG+T
Sbjct: 623 IDLVNGYQCNCQPG---TSGVN-CEINFDDCASNP-CIHGICMDGINRYSCVCSPGFTGQ 677
Query: 185 RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVD-VNECREGGMV 242
R N+ D+DEC+ P + TC N + C C +G P++ C VNEC
Sbjct: 678 RCNI--DIDECAS-NPCRKGATCINGVNGFRCICPEG----PHHPSCYSQVNECLSNP-- 728
Query: 243 CRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC 302
C +G C + ++C C G+ G NC +VD+ + L +PC G +C N GY C
Sbjct: 729 CIHGNCTGGLSGYKCLCDAGWV----GINC-EVDKNECLSNPCQNGG--TCDNLVNGYRC 781
Query: 303 SCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCEC--------------PAG 347
+C G+K G C V+ DEC P + G C + GY C C P
Sbjct: 782 TCKKGFK--GYNCQVNIDECASNPCLNQG-TCFDDISGYTCHCVLPYTGKNCQTVLAPCS 838
Query: 348 WRFDKTAAVCVDERKE-----LCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERC 402
+ AAVC + LC W+ RC +++P C + G C
Sbjct: 839 PNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKP--CMNHGL-----CHNT 891
Query: 403 PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAP 461
+M C G + +D+D+C P C GG C++ +F C C G+
Sbjct: 892 ----QGSYMCECPPGFSGMDCEEDIDDCLANP--CQNGGSCMDGVNTFSCLCLPGFT--G 943
Query: 462 DGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASC 520
D D +EC +P C NG TCS+ Y C+C GF + +++EC E
Sbjct: 944 DKYQ-TDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGFDGVHCEN--NINECTESSCFN 998
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVCPHACENVVGSYICKCPEG 579
C + SF C CP G+ G C +I+EC P + C + +G+Y C CP G
Sbjct: 999 GGTCVDGINSFSCLCPVGFT----GSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLG 1054
Query: 580 YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
Y + Q N C + C+ + G C+ C C +G+
Sbjct: 1055 YTGKNC-QTLVNLCSR-SPCKNK------GTCVQKKAESQCLCPSGW 1093
Score = 204 bits (498), Expect = 1e-51
Identities = 172/589 (29%), Positives = 244/589 (41%), Gaps = 85/589 (14%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCV 127
D+C P C G C D + C C G+ T C D+DEC+ PCR A C+
Sbjct: 647 DDCASNP--CIHGICMDGINRYSCVCSPGF----TGQRCNIDIDECASN--PCRKGATCI 698
Query: 128 NLPGAFECRCPPGYRLTPSLDEC-EDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
N F C CP G P C V+EC C HG+C + Y+C C G+ +
Sbjct: 699 NGVNGFRCICPEG----PHHPSCYSQVNECLSNP-CIHGNCTGGLSGYKCLCDAGW-VGI 752
Query: 187 NVCRDVDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCR 244
N D +EC S P C+NG TC+NL Y C C GFK N V+++EC +
Sbjct: 753 NCEVDKNECLSNP---CQNGGTCDNLVNGYRCTCKKGFKG--YNCQVNIDECASNPCL-N 806
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDV-DECDELPHPCGRDGNPSCTNTNGGYECS 303
G C + + + C C YT G+NC+ V C P+PC + Y C
Sbjct: 807 QGTCFDDISGYTCHCVLPYT----GKNCQTVLAPCS--PNPCENAAVCKESPNFESYTCL 860
Query: 304 CGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
C GW+ G+RC +D DEC P + G C N G Y+CECP G+ + C ++
Sbjct: 861 CAPGWQ--GQRCTIDIDECISKPCM-NHGLCHNTQGSYMCECPPGF----SGMDCEED-- 911
Query: 363 ELCYDEWEAGRCHRARPLQ--LARPECCCSEGAAWGRY------CERCPAPDSA------ 408
D+ A C + C C G +Y C P +
Sbjct: 912 ---IDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKYQTDMNECLSEPCKNGGTCSDYV 968
Query: 409 -EFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
+ CQ G + +++EC GG CV+ SF C CP G+ G C+
Sbjct: 969 NSYTCKCQAGFDGVHCENNINEC-TESSCFNGGTCVDGINSFSCLCPVGFT----GSFCL 1023
Query: 468 -DADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHN 526
+ +EC+ P + GTC + G Y C C G+T QT V++ C+ C
Sbjct: 1024 HEINECSSHPCL-NEGTCVDGLGTYRCSCPLGYTGKNCQTLVNL--CSRSPCKNKGTCVQ 1080
Query: 527 TAGSFRCTCPYGYAVA---ADGVHCRDIDEC---VQEPRVCPHA--CENVVGSYICKCPE 578
+C CP G+A A V C DI V +C H+ C N ++ C+CP
Sbjct: 1081 KKAESQCLCPSGWAGAYCDVPNVSC-DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPL 1139
Query: 579 GYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
GY + + + N C+ G C + G + C+C G++
Sbjct: 1140 GYTGSYCEEQLDECAS--NPCQH------GATCSDFIGGYRCECVPGYQ 1180
Score = 198 bits (482), Expect = 9e-50
Identities = 184/673 (27%), Positives = 265/673 (39%), Gaps = 99/673 (14%)
Query: 21 YLCCCSVGHA-----WGAPCEACPPRGSPAHTALCGEKPGEYINPVTNET--KPIDECDI 73
Y C C VG W C + P T + + + + T + ++ECDI
Sbjct: 129 YECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 188
Query: 74 MPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG-A 132
GTC + P +QC C G+ T C D PC C
Sbjct: 189 PGHCQHGGTCLNLPGSYQCQCPQGF----TGQYC-DSLYVPCAPSPCVNGGTCRQTGDFT 243
Query: 133 FECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRD 191
FEC C PG+ + CE ++D+C + R + G C + + +Y C C P +T + D
Sbjct: 244 FECNCLPGFEGS----TCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWT-GQFCTED 298
Query: 192 VDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVD-VNECREGGMVCRNG-RC 248
VDEC C+N GTC N G Y C C +G+ +DC + +++C C G C
Sbjct: 299 VDECLLQPNACQNGGTCANRNGGYGCVCVNGWS---GDDCSENIDDCAFAS--CTPGSTC 353
Query: 249 RNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
+ V SF C C G G C D C + +PC + NG Y C+C G+
Sbjct: 354 IDRVASFSCMCPEGKA----GLLCHLDDAC--ISNPCHKGALCDTNPLNGQYICTCPQGY 407
Query: 309 KLVGRRCV-DRDECKEL-PYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
K G C D DEC C G+C N +G + CEC G+ R E+
Sbjct: 408 K--GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY---------AGPRCEMD 456
Query: 366 YDEWEAGRCHRARPL--QLARPECCCSEGAAWGRYCE----RC---PAPDSAE------- 409
+E + C ++ C C G G +CE C P ++ +
Sbjct: 457 INECHSDPCQNDATCLDKIGGFTCLCMPGFK-GVHCELEINECQSNPCVNNGQCVDKVNR 515
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
F +C G P D+D+C P C+ G +C++ + C+C G+ G+ C +
Sbjct: 516 FQCLCPPGFTGPVCQIDIDDCSSTP--CLNGAKCIDHPNGYECQCATGFT----GVLCEE 569
Query: 469 -ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHN 526
D C DP C +G C + Y C C+PG+ C D +DEC RC +
Sbjct: 570 NIDNC--DPDPCHHGQCQDGIDSYTCICNPGYM---GAICSDQIDECYSSPCLNDGRCID 624
Query: 527 TAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTS 584
++C C G GV+C + D+C P C H C + + Y C C G+
Sbjct: 625 LVNGYQCNCQPG----TSGVNCEINFDDCASNP--CIHGICMDGINRYSCVCSPGF---- 674
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG-FEPS--EDGTDCIDRRT- 640
+ DI+EC G CIN F C C G PS +C+
Sbjct: 675 ---TGQRCNIDIDEC-ASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCI 730
Query: 641 -GTCYRSLVSGRC 652
G C L +C
Sbjct: 731 HGNCTGGLSGYKC 743
Score = 182 bits (442), Expect = 6e-45
Identities = 193/682 (28%), Positives = 275/682 (40%), Gaps = 101/682 (14%)
Query: 10 CAGAVGVPQTKYLCCCSVGHAWGAPCE--ACPPRGSPAHTALCGEKPGEYINPVTNETKP 67
C A G T LC ++ + PC C G ++T +C PG Y+ + ++
Sbjct: 556 CQCATGF--TGVLCEENIDNCDPDPCHHGQCQD-GIDSYTCICN--PG-YMGAICSDQ-- 607
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P L G C D G+QC C G N + D+C+ P G+ C+
Sbjct: 608 IDECYSSPCL-NDGRCIDLVNGYQCNCQPGTSGVNCEI---NFDDCA-SNPCIHGI--CM 660
Query: 128 NLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
+ + C C PG+ + C D+DEC C N + +RC C G
Sbjct: 661 DGINRYSCVCSPGF----TGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG-PHHP 715
Query: 187 NVCRDVDEC-SRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN 245
+ V+EC S P C +G C Y C CD G+ G N + VD NEC C+N
Sbjct: 716 SCYSQVNECLSNP---CIHGNCTGGLSGYKCLCDAGW-VGINCE-VDKNECLSNP--CQN 768
Query: 246 G-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECS 303
G C N V +RC C G+ G NC+ ++DEC +PC G +C + GY C
Sbjct: 769 GGTCDNLVNGYRCTCKKGFK----GYNCQVNIDECAS--NPCLNQG--TCFDDISGYTCH 820
Query: 304 CGAGWKLVGRRCVD-RDECKELPYVCAG--GECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
C + G+ C C P A E NF Y C C GW+ + + +DE
Sbjct: 821 CVLPY--TGKNCQTVLAPCSPNPCENAAVCKESPNFES-YTCLCAPGWQGQR-CTIDIDE 876
Query: 361 R-KELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCER----C---PAPDSAE--- 409
+ C + G CH + + C C G + G CE C P +
Sbjct: 877 CISKPCMNH---GLCHNTQGSYM----CECPPGFS-GMDCEEDIDDCLANPCQNGGSCMD 928
Query: 410 ----FMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGL 464
F +C G D++EC P C GG C + S+ C+C G+ DG+
Sbjct: 929 GVNTFSCLCLPGFTGDKYQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGF----DGV 982
Query: 465 SCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRASCTF 522
C + +EC + GTC + + C C GFT C+ +++EC+
Sbjct: 983 HCENNINECT-ESSCFNGGTCVDGINSFSCLCPVGFT---GSFCLHEINECSSHPCLNEG 1038
Query: 523 RCHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + G++RC+CP GY G +C+ ++ C + P C C CP G+
Sbjct: 1039 TCVDGLGTYRCSCPLGYT----GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW- 1093
Query: 582 RTSAPQDSENACEDINECEEQ---EDLCS-GGVCINTDGSFLCDCDAGFEPS---EDGTD 634
A D N DI E LC GVCIN + C C G+ S E +
Sbjct: 1094 -AGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDE 1152
Query: 635 CID---RRTGTCYRSLVSGRCE 653
C + TC + RCE
Sbjct: 1153 CASNPCQHGATCSDFIGGYRCE 1174
Score = 178 bits (434), Expect = 6e-44
Identities = 172/589 (29%), Positives = 237/589 (40%), Gaps = 86/589 (14%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
IDEC P C+ G TC + GF+C C G H + V+EC P G C
Sbjct: 683 IDECASNP--CRKGATCINGVNGFRCICPEGPHHPSCYS---QVNECL-SNPCIHG--NC 734
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
++C C G+ CE D +EC + G C N + YRC CK G+
Sbjct: 735 TGGLSGYKCLCDAGWVGI----NCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK-G 789
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCV----DVNECREGGM 241
N ++DEC+ P GTC + Y CHC + G N V N C E
Sbjct: 790 YNCQVNIDECAS-NPCLNQGTCFDDISGYTCHCVLPY-TGKNCQTVLAPCSPNPC-ENAA 846
Query: 242 VCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGY 300
VC+ S+ C CAPG+ G+ C D+DEC + PC G C NT G Y
Sbjct: 847 VCKESP---NFESYTCLCAPGW----QGQRCTIDIDEC--ISKPCMNHG--LCHNTQGSY 895
Query: 301 ECSCGAGWKLVGRRCV-DRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAA--- 355
C C G+ G C D D+C P C GG C + + C C G+ DK
Sbjct: 896 MCECPPGFS--GMDCEEDIDDCLANP--CQNGGSCMDGVNTFSCLCLPGFTGDKYQTDMN 951
Query: 356 VCVDERKE---LCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
C+ E + C D + C E +E + F
Sbjct: 952 ECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSC 1011
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVD-AD 470
+C G +++EC P C+ G CV+ G++RC CP GY G +C +
Sbjct: 1012 LCPVGFTGSFCLHEINECSSHP--CLNEGTCVDGLGTYRCSCPLGYT----GKNCQTLVN 1065
Query: 471 ECALDPRICGN-GTCSNTRGGYECQCSPGFTQG----PDQTCVDVDECAEG---RASCTF 522
C+ P C N GTC + +C C G+ P+ +C D+ G C
Sbjct: 1066 LCSRSP--CKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSC-DIAASRRGVLVEHLCQH 1122
Query: 523 R--CHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPHA--CENVVGSYICKCP 577
C N + C CP GY G +C + +DEC P C H C + +G Y C+C
Sbjct: 1123 SGVCINAGNTHYCQCPLGYT----GSYCEEQLDECASNP--CQHGATCSDFIGGYRCECV 1176
Query: 578 EGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
GY+ + CE +++EC+ Q +GG CI+ F C C G
Sbjct: 1177 PGYQGVN--------CEYEVDECQNQ-PCQNGGTCIDLVNHFKCSCPPG 1216
Score = 177 bits (430), Expect = 2e-43
Identities = 159/549 (28%), Positives = 217/549 (39%), Gaps = 85/549 (15%)
Query: 112 ECSWGRPPCRGMAQCVNLP-GAFECRCPPGYRLTPSLDE-CEDVDECGDQRICDHGDC-- 167
+C G PC CV G C+CP G+ L E C+ D C R + G C
Sbjct: 27 QCRDGYEPCVNEGMCVTYHNGTGYCKCPEGF-----LGEYCQHRDPCEKNRCQNGGTCVA 81
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLP-GAYLCHCDDGFKAGP 226
+ +G C C G+T + C RP GTC L Y C C GF
Sbjct: 82 QAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGF---T 138
Query: 227 NNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHP 284
+C + C C NG C F C+C G+T G+ C DV+ECD +P
Sbjct: 139 GKECQWTDACL--SHPCANGSTCTTVANQFSCKCLTGFT----GQKCETDVNECD-IPGH 191
Query: 285 CGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNG-GYVC 342
C G +C N G Y+C C G+ G+ C D P C GG CR + C
Sbjct: 192 CQHGG--TCLNLPGSYQCQCPQGF--TGQYC-DSLYVPCAPSPCVNGGTCRQTGDFTFEC 246
Query: 343 ECPAGWRFD--------------KTAAVCVDERKEL---CYDEWEAGRCHRARPLQLARP 385
C G+ + VCVD C +W C L +P
Sbjct: 247 NCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP 306
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNT 445
C + G R + + +C G + ++++D+C G C++
Sbjct: 307 NACQNGGTCANR---------NGGYGCVCVNGWSGDDCSENIDDCAF-ASCTPGSTCIDR 356
Query: 446 DGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNT---RGGYECQCSPGFTQG 502
SF C CP+G GL C D C +P C G +T G Y C C G+ +G
Sbjct: 357 VASFSCMCPEGKA----GLLCHLDDACISNP--CHKGALCDTNPLNGQYICTCPQGY-KG 409
Query: 503 PDQTCVDVDECAEGRAS-CTF--RCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEP 558
D T DVDECA ++ C +C NT G+F C C GYA G C DI+EC +P
Sbjct: 410 ADCT-EDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDP 464
Query: 559 RVCPHACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGS 617
C + +G + C C G++ CE +INEC + + G C++
Sbjct: 465 CQNDATCLDKIGGFTCLCMPGFKGVH--------CELEINEC-QSNPCVNNGQCVDKVNR 515
Query: 618 FLCDCDAGF 626
F C C GF
Sbjct: 516 FQCLCPPGF 524
Score = 173 bits (422), Expect = 2e-42
Identities = 152/542 (28%), Positives = 220/542 (40%), Gaps = 72/542 (13%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
++EC P C G C +G++C CD G+ N D +EC PC+ C
Sbjct: 721 VNECLSNP--CIHGNCTGGLSGYKCLCDAGWVGINCEV---DKNECLSN--PCQNGGTCD 773
Query: 128 NLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
NL + C C G++ C+ ++DEC + G C + I Y C C YT +
Sbjct: 774 NLVNGYRCTCKKGFKGY----NCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKN 829
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPG--AYLCHCDDGFKAGPNNDCVDVNECREGGMVCR 244
C+ V P P C+ P +Y C C G++ +D++EC C
Sbjct: 830 --CQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQG--QRCTIDIDECIS--KPCM 883
Query: 245 N-GRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYEC 302
N G C NT GS+ CEC PG++ G +C D+D+C L +PC G SC + + C
Sbjct: 884 NHGLCHNTQGSYMCECPPGFS----GMDCEEDIDDC--LANPCQNGG--SCMDGVNTFSC 935
Query: 303 SCGAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDER 361
C G+ + D +EC P C GG C ++ Y C+C AG FD C +
Sbjct: 936 LCLPGFT-GDKYQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAG--FD--GVHCENNI 988
Query: 362 KELCYDE-WEAGRCHRARPLQLARPECCCSEGAAWGRYC----ERCPAPDSAEFMRICQG 416
E + G C + C C G G +C C + C
Sbjct: 989 NECTESSCFNGGTCVDG----INSFSCLCPVGFT-GSFCLHEINECSSHPCLN-EGTCVD 1042
Query: 417 GMGRPNLTQDLD----ECRVRPDVCVG------GRCVNTDGSFRCECPDGYVLAPDGLSC 466
G+G + L C+ ++C G CV +C CP G+ A +
Sbjct: 1043 GLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPN 1102
Query: 467 VDADECA-----LDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASC 520
V D A L +C + G C N + CQC G+T + +DECA
Sbjct: 1103 VSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEE--QLDECASNPCQH 1160
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEG 579
C + G +RC C GY GV+C ++DEC +P C ++V + C CP G
Sbjct: 1161 GATCSDFIGGYRCECVPGY----QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG 1216
Query: 580 YR 581
R
Sbjct: 1217 TR 1218
Score = 140 bits (340), Expect = 1e-32
Identities = 122/428 (28%), Positives = 176/428 (41%), Gaps = 64/428 (14%)
Query: 75 PQLCK-PGTCHDTPT--GFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPG 131
P C+ C ++P + C C G++ + D+DEC PC C N G
Sbjct: 839 PNPCENAAVCKESPNFESYTCLCAPGWQGQRCTI---DIDECI--SKPCMNHGLCHNTQG 893
Query: 132 AFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRD 191
++ C CPPG+ +D ED+D+C + G C + + ++ C C PG+T + D
Sbjct: 894 SYMCECPPGFS---GMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFT-GDKYQTD 949
Query: 192 VDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RC 248
++EC S P C+NG TC + +Y C C GF + ++NEC E C NG C
Sbjct: 950 MNECLSEP---CKNGGTCSDYVNSYTCKCQAGFDGVHCEN--NINECTESS--CFNGGTC 1002
Query: 249 RNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
+ + SF C C G+T G C +++EC HPC +G +C + G Y CSC G
Sbjct: 1003 VDGINSFSCLCPVGFT----GSFCLHEINECSS--HPCLNEG--TCVDGLGTYRCSCPLG 1054
Query: 308 WKLVGRRCVDR-DECKELPYVCAG-GECRNFNGGYVCECPAGWRF------DKTAAVCVD 359
+ G+ C + C P C G C C CP+GW + + +
Sbjct: 1055 Y--TGKNCQTLVNLCSRSP--CKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAAS 1110
Query: 360 ER----KELCYDEW---EAGRCHRAR-PLQLARPEC------CCSEGAAWGRYCERCPAP 405
R + LC AG H + PL C C S G C
Sbjct: 1111 RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGG 1170
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGL 464
E C G N ++DEC+ +P C GG C++ F+C CP G L
Sbjct: 1171 YRCE----CVPGYQGVNCEYEVDECQNQP--CQNGGTCIDLVNHFKCSCPPGTRGMKSSL 1224
Query: 465 SCVDADEC 472
S C
Sbjct: 1225 SIFHPGHC 1232
Score = 125 bits (301), Expect = 8e-28
Identities = 94/305 (30%), Positives = 138/305 (45%), Gaps = 35/305 (11%)
Query: 62 TNETKPIDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
T + D + + + CK G TC D + C C G++ H +++EC+ C
Sbjct: 942 TGDKYQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDG---VHCENNINECT--ESSC 996
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
CV+ +F C CP G+ + L E ++EC + G C + +G+YRC C
Sbjct: 997 FNGGTCVDGINSFSCLCPVGFTGSFCLHE---INECSSHPCLNEGTCVDGLGTYRCSCPL 1053
Query: 181 GYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG----PNNDCVDVNEC 236
GYT +N V+ CSR P GTC C C G+ PN C D+
Sbjct: 1054 GYT-GKNCQTLVNLCSRS-PCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSC-DIAAS 1110
Query: 237 REGGMV---CRN-GRCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNP 291
R G +V C++ G C N + C+C GYT G C + +DEC +PC
Sbjct: 1111 RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT----GSYCEEQLDECAS--NPCQHGA-- 1162
Query: 292 SCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWR 349
+C++ GGY C C G++ G C + DEC+ P C GG C + + C CP G R
Sbjct: 1163 TCSDFIGGYRCECVPGYQ--GVNCEYEVDECQNQP--CQNGGTCIDLVNHFKCSCPPGTR 1218
Query: 350 FDKTA 354
K++
Sbjct: 1219 GMKSS 1223
Score = 112 bits (269), Expect = 6e-24
Identities = 116/442 (26%), Positives = 159/442 (35%), Gaps = 58/442 (13%)
Query: 439 GGRCVNTD--GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSN-TRGGYECQC 495
GG CV G C C G+ + + C + GTC +R YEC C
Sbjct: 76 GGTCVAQAMLGKATCRCASGFT--GEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC 133
Query: 496 SPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDEC 554
GFT + C D C + C A F C C G+ G C D++EC
Sbjct: 134 QVGFT---GKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFT----GQKCETDVNEC 186
Query: 555 VQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCI 612
P C H C N+ GSY C+CP+G+ + C+ + +GG C
Sbjct: 187 -DIPGHCQHGGTCLNLPGSYQCQCPQGF--------TGQYCDSLYVPCAPSPCVNGGTCR 237
Query: 613 NT-DGSFLCDCDAGFEPS---EDGTDCIDRRT---GTCYRSL--VSGRCEPEXXXXXXXX 663
T D +F C+C GFE S + DC + R G C + + RC P+
Sbjct: 238 QTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTE 297
Query: 664 XXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSEC-ELCPAPGSPARLDLCTAVNLTPXXX 722
G C +G C +D C + TP
Sbjct: 298 DVDECLLQPNACQNGGT-----CANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGST 352
Query: 723 XXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP----GLCAP----GRFRCVCGPGYRPA 774
L D D C + P LC G++ C C GY+ A
Sbjct: 353 CIDRVASFSCMCPEGKAGLL-CHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGA 410
Query: 775 GEVCADVDECAV-RPPPCDQL--CHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTH 830
+ DVDECA+ PC+ C NTDG++ C C GY G C D++EC D
Sbjct: 411 -DCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDPC 465
Query: 831 TCQQICSNTEGSYECSCEDGYE 852
C + G + C C G++
Sbjct: 466 QNDATCLDKIGGFTCLCMPGFK 487
Score = 106 bits (255), Expect = 3e-22
Identities = 101/349 (28%), Positives = 143/349 (40%), Gaps = 45/349 (12%)
Query: 21 YLCCCSVGHAW-GAPC----EACPPRGSPAHTALCGEKPGEYINPVTNETKPID-ECDIM 74
Y C C+ G W G C + C + H LC G Y+ +D E DI
Sbjct: 857 YTCLCAPG--WQGQRCTIDIDECISKPCMNH-GLCHNTQGSYMCECPPGFSGMDCEEDID 913
Query: 75 PQLCKP----GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLP 130
L P G+C D F C C G+ D D++EC PC+ C +
Sbjct: 914 DCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKYQ---TDMNECL--SEPCKNGGTCSDYV 968
Query: 131 GAFECRCPPGYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVC 189
++ C+C G+ CE+ ++EC + + G C + I S+ C C G+T + C
Sbjct: 969 NSYTCKCQAGFDGV----HCENNINECTESSCFNGGTCVDGINSFSCLCPVGFT--GSFC 1022
Query: 190 -RDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GR 247
+++ECS P GTC + G Y C C G+ G N + VN C C+N G
Sbjct: 1023 LHEINECSS-HPCLNEGTCVDGLGTYRCSCPLGY-TGKNCQTL-VNLCSRSP--CKNKGT 1077
Query: 248 CRNTVGSFRCECAPGYT-LTADGRNCR-DVDECDE---LPHPCGRDGNPSCTNTNGGYEC 302
C +C C G+ D N D+ + H C G C N + C
Sbjct: 1078 CVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSG--VCINAGNTHYC 1135
Query: 303 SCGAGWKLVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCECPAGWR 349
C G+ G C ++ DEC P C G C +F GGY CEC G++
Sbjct: 1136 QCPLGY--TGSYCEEQLDECASNP--CQHGATCSDFIGGYRCECVPGYQ 1180
Score = 60.5 bits (140), Expect = 2e-08
Identities = 35/108 (32%), Positives = 51/108 (47%), Gaps = 12/108 (11%)
Query: 756 GLCAPG--RFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY 810
G+C G + C C P + G+ C DVDEC ++P C C N +G Y C+C G+
Sbjct: 273 GVCVDGVNTYNCRCPPQW--TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGW 330
Query: 811 ELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
D+ N +D+C + T C + S+ C C +G K G C
Sbjct: 331 SGDDCSEN---IDDCAFASCTPGSTCIDRVASFSCMCPEG--KAGLLC 373
Score = 52.0 bits (119), Expect = 9e-06
Identities = 33/99 (33%), Positives = 43/99 (43%), Gaps = 10/99 (10%)
Query: 756 GLC--APGRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G+C A C C GY G C + +DECA P C + G Y C C GY+
Sbjct: 1124 GVCINAGNTHYCQCPLGY--TGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQ- 1180
Query: 813 DEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDG 850
G NC +VDEC+ C + ++CSC G
Sbjct: 1181 ---GVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG 1216
Score = 42.7 bits (96), Expect = 0.005
Identities = 33/115 (28%), Positives = 53/115 (46%), Gaps = 18/115 (15%)
Query: 747 DVDECAAIP----GLCAP--GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTD 799
D++EC + P G C+ + C C G+ G C + ++EC C +
Sbjct: 949 DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD--GVHCENNINECTESSCFNGGTCVDGI 1006
Query: 800 GSYDCLCRTGYELDEDGANC-RDVDECERDTHTC--QQICSNTEGSYECSCEDGY 851
S+ CLC G+ G+ C +++EC +H C + C + G+Y CSC GY
Sbjct: 1007 NSFSCLCPVGFT----GSFCLHEINECS--SHPCLNEGTCVDGLGTYRCSCPLGY 1055
Score = 41.9 bits (94), Expect = 0.009
Identities = 35/122 (28%), Positives = 49/122 (40%), Gaps = 18/122 (14%)
Query: 747 DVDECAAIP----GLC--APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D +EC + P G C +RC C G++ G C ++DECA P C +
Sbjct: 757 DKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK--GYNCQVNIDECASNPCLNQGTCFDDI 814
Query: 800 GSYDCLCRTGYELDEDGANCRDV-DECERDTHTCQQICSNTEG--SYECSCEDGYEKRGD 856
Y C C Y G NC+ V C + +C + SY C C G++ G
Sbjct: 815 SGYTCHCVLPY----TGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ--GQ 868
Query: 857 AC 858
C
Sbjct: 869 RC 870
Score = 38.3 bits (85), Expect = 0.11
Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+C N ++ C C GY G+ C + +DEC + CS+ G Y C C GY+
Sbjct: 1125 VCINAGNTHYCQCPLGYT----GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQ 1180
>X53743-1|CAA37772.1| 683|Homo sapiens fibulin-1 C protein.
Length = 683
Score = 219 bits (535), Expect = 3e-56
Identities = 151/437 (34%), Positives = 208/437 (47%), Gaps = 61/437 (13%)
Query: 193 DECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGR-CRN 250
D C P C+ C + +C C G++ + C DVNEC G CR G C N
Sbjct: 178 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 251 TVGSFRCE----CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC---- 302
TVGSFRC+ C GY LT D +C+D+DEC+ H C D C NT G + C
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDF--ICQNTLGSFRCRPKL 292
Query: 303 SCGAGW--KLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCE-----CPAGWRFDKTA 354
C +G+ +G C+D +EC + C G C N G Y C+ C G+ ++
Sbjct: 293 QCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEG 351
Query: 355 AVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC 414
CVD E G+ HR C S G+ RC F
Sbjct: 352 TRCVDV-DECAPPAEPCGKGHR----------CVNSPGSF------RCECKTGYYF---- 390
Query: 415 QGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECAL 474
G+ R + D++EC+ P G +C NT GS+ C C G+ L+ DG SC D +EC+
Sbjct: 391 -DGISR--MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 475 DPRICGNGTCSNTRGGYECQCSPGF--TQGPDQTCVDVDECA--EGRASCTFRCHNTAGS 530
P C C+N G Y+C C G+ + TC D+DECA G C++RC N GS
Sbjct: 448 SP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 504
Query: 531 FRCTCP-YGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC---KCPEGYRRTS 584
F+C+CP GY +A +G +C+DIDECV C C N+ G++ C +CPE YRR++
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENYRRSA 564
Query: 585 APQDSENACEDINECEE 601
A + C + EC +
Sbjct: 565 ATRCERLPCHENRECSK 581
Score = 208 bits (508), Expect = 6e-53
Identities = 147/407 (36%), Positives = 200/407 (49%), Gaps = 53/407 (13%)
Query: 234 NECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+ CR GG C+ +CR+T C C GY L +DG +C DV+EC H C R G SC
Sbjct: 178 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC-RLGE-SC 233
Query: 294 TNTNGGYEC----SCGAGWKLV-GRRCVDRDECKELPYVCAGGE-CRNFNGGYVC----E 343
NT G + C SCG G++L C D DEC+ + C C+N G + C +
Sbjct: 234 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
C +G+ D C+D + L + P + C +EG+ C++
Sbjct: 294 CKSGFIQDALGN-CIDINECLSI----------SAPCPIGHT-CINTEGSYT---CQK-N 337
Query: 404 APDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPD 462
P+ + + G D+DEC + C G RCVN+ GSFRCEC GY D
Sbjct: 338 VPNCGRGYHLNEEG----TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF--D 391
Query: 463 GLS--CVDADECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRA 518
G+S CVD +EC P R+CG+ C NT G Y C CS GF D ++C D++EC+ +
Sbjct: 392 GISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS--S 448
Query: 519 SCTFRCHNTAGSFRCTCPYGYAVA-ADGVHCRDIDECVQEP--RVCPHACENVVGSYICK 575
C+ C N GS++C C GY ++ DGV C DIDEC +C + C N+ GS+ C
Sbjct: 449 PCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCS 508
Query: 576 CP-EGYRRTSAPQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
CP GYR AP C+DI+EC CS C N G+F C
Sbjct: 509 CPSSGYR--LAPNGRN--CQDIDECVTGIHNCSINETCFNIQGAFRC 551
Score = 207 bits (506), Expect = 1e-52
Identities = 142/434 (32%), Positives = 193/434 (44%), Gaps = 61/434 (14%)
Query: 111 DECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GDQRICDHGD-CR 168
D C G P C+ QC + C C GY+L CEDV+EC C G+ C
Sbjct: 178 DRCRGGGP-CK--QQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCI 234
Query: 169 NTIGSYRCE----CKPGYTLRE-NVCRDVDECSRPRPVCR-NGTCENLPGAYLCH----C 218
NT+GS+RC+ C GY L E N C+D+DEC C + C+N G++ C C
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294
Query: 219 DDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCE-----CAPGYTLTADGRNC 272
GF +C+D+NEC C G C NT GS+ C+ C GY L +G C
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354
Query: 273 RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAG 330
DVDEC PCG+ C N+ G + C C G+ G R CVD +EC+ P G
Sbjct: 355 VDVDECAPPAEPCGKGHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCS 390
+C N G Y+C C G+R C D +E + C + C +
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDGRSCED------INECSSSPCSQE----------CAN 456
Query: 391 EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP--DVCVGGRCVNTDGS 448
++ YC R + + C +D+DEC + +C RC+N GS
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGV-TC----------EDIDECALPTGGHIC-SYRCINIPGS 504
Query: 449 FRCECP-DGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC---QCSPGFTQGP 503
F+C CP GY LAP+G +C D DEC C N TC N +G + C +C + +
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENYRRSA 564
Query: 504 DQTCVDVDECAEGR 517
C + C E R
Sbjct: 565 ATRCERL-PCHENR 577
Score = 193 bits (471), Expect = 2e-48
Identities = 143/428 (33%), Positives = 184/428 (42%), Gaps = 59/428 (13%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECR- 136
CK C DT C C GY+ + C DV+EC G CR C+N G+F C+
Sbjct: 186 CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 137 ---CPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIGSYRC----ECKPGYTLRE- 186
C GY LT + C+D+DEC G C+NT+GS+RC +CK G+
Sbjct: 245 DSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 187 NVCRDVDECSRPRPVCRNG-TCENLPGAYLC-----HCDDGFKAGPNND-CVDVNECREG 239
C D++EC C G TC N G+Y C +C G+ CVDV+EC
Sbjct: 304 GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPP 363
Query: 240 GMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
C G RC N+ GSFRCEC GY R C DV+EC P GR C NT G
Sbjct: 364 AEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYP---GRLCGHKCENTLG 420
Query: 299 GYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
Y CSC G++L GR C D +EC P C+ EC N G Y C C G++ V
Sbjct: 421 SYLCSCSVGFRLSVDGRSCEDINECSSSP--CS-QECANVYGSYQCYCRRGYQLSDVDGV 477
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
++ E C + C G+ +C P S R+
Sbjct: 478 TCEDIDE----------CALPTGGHICSYRCINIPGSF------QCSCPSSG--YRLAPN 519
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRC---ECPDGY----VLAPDGLSCVD 468
G QD+DEC C + C N G+FRC ECP+ Y + L C +
Sbjct: 520 GRN----CQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENYRRSAATRCERLPCHE 575
Query: 469 ADECALDP 476
EC+ P
Sbjct: 576 NRECSKLP 583
Score = 175 bits (427), Expect = 4e-43
Identities = 127/374 (33%), Positives = 174/374 (46%), Gaps = 52/374 (13%)
Query: 287 RDGNP---SCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGE-CRNFNGGY 340
R G P C +T CSC G++L+ G C D +EC + C GE C N G +
Sbjct: 181 RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 240
Query: 341 VCE----CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWG 396
C+ C G+ + + C D DE E+G + P+ C G
Sbjct: 241 RCQRDSSCGTGYELTEDNS-CKD------IDECESG-------IHNCLPDFICQN--TLG 284
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCE--- 452
+ RC P Q +G D++EC C +G C+NT+GS+ C+
Sbjct: 285 SF--RC-RPKLQCKSGFIQDALGN---CIDINECLSISAPCPIGHTCINTEGSYTCQKNV 338
Query: 453 --CPDGYVLAPDGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFT-QGPDQTCV 508
C GY L +G CVD DECA CG G C N+ G + C+C G+ G + CV
Sbjct: 339 PNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV 398
Query: 509 DVDECAE--GRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
DV+EC GR C +C NT GS+ C+C G+ ++ DG C DI+EC P C C
Sbjct: 399 DVNECQRYPGRL-CGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQECA 455
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED--LCSGGVCINTDGSFLCDC-D 623
NV GSY C C GY+ + + CEDI+EC +CS CIN GSF C C
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVT---CEDIDECALPTGGHICSYR-CINIPGSFQCSCPS 511
Query: 624 AGFEPSEDGTDCID 637
+G+ + +G +C D
Sbjct: 512 SGYRLAPNGRNCQD 525
Score = 165 bits (400), Expect = 8e-40
Identities = 94/250 (37%), Positives = 127/250 (50%), Gaps = 22/250 (8%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQC-----GCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
I+EC + C G TC +T + C C GY + C DVDEC+ PC
Sbjct: 309 INECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCG 368
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG--DQRICDHGDCRNTIGSYRCECK 179
+CVN PG+F C C GY C DV+EC R+C H C NT+GSY C C
Sbjct: 369 KGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCS 427
Query: 180 PGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN--DCVDVNE 235
G+ L + C D++ECS P + C N+ G+Y C+C G++ + C D++E
Sbjct: 428 VGFRLSVDGRSCEDINECS-SSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDE 484
Query: 236 CR--EGGMVCRNGRCRNTVGSFRCEC-APGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
C GG +C + RC N GSF+C C + GY L +GRNC+D+DEC H C N +
Sbjct: 485 CALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI--NET 541
Query: 293 CTNTNGGYEC 302
C N G + C
Sbjct: 542 CFNIQGAFRC 551
Score = 151 bits (365), Expect = 1e-35
Identities = 91/247 (36%), Positives = 112/247 (45%), Gaps = 26/247 (10%)
Query: 425 QDLDECRVRPDVC-VGGRCVNTDGSFRCE----CPDGYVLAPDGLSCVDADECALDPRIC 479
+D++EC C +G C+NT GSFRC+ C GY L D SC D DEC C
Sbjct: 215 EDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNC 273
Query: 480 -GNGTCSNTRGGYEC----QCSPGFTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFR 532
+ C NT G + C QC GF Q C+D++EC A C C NT GS+
Sbjct: 274 LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 533 C-----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSA 585
C C GY + +G C D+DEC C H C N GS+ C+C GY
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 586 PQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYR 645
+ C D+NEC+ G C NT GS+LC C GF S DG C D C
Sbjct: 394 SR----MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED--INECSS 447
Query: 646 SLVSGRC 652
S S C
Sbjct: 448 SPCSQEC 454
Score = 136 bits (328), Expect = 4e-31
Identities = 90/266 (33%), Positives = 122/266 (45%), Gaps = 33/266 (12%)
Query: 416 GGMGRPNLTQDLDECRVRP---DVCVGG-----RCVNTDGSFRCECPDGYVLAPDGLSCV 467
GG+ + +++E + P D C GG +C +T C C GY L DG+SC
Sbjct: 156 GGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCE 215
Query: 468 DADECALDPRICGNG-TCSNTRGGYECQ----CSPGFTQGPDQTCVDVDECAEGRASC-- 520
D +EC C G +C NT G + CQ C G+ D +C D+DEC G +C
Sbjct: 216 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLP 275
Query: 521 TFRCHNTAGSFRC----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC 574
F C NT GSFRC C G+ A G +C DI+EC+ CP H C N GSY C
Sbjct: 276 DFICQNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTC 334
Query: 575 K-----CPEGYRRTSAPQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFEP 628
+ C GY + C D++EC + C G C+N+ GSF C+C G+
Sbjct: 335 QKNVPNCGRGYHL----NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 629 SEDGTDCIDRRTGTCYRSLVSG-RCE 653
C+D Y + G +CE
Sbjct: 391 DGISRMCVDVNECQRYPGRLCGHKCE 416
Score = 100 bits (239), Expect = 3e-20
Identities = 61/193 (31%), Positives = 90/193 (46%), Gaps = 18/193 (9%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C K G Y + ++ ++EC P C +T + C C G+ C D
Sbjct: 382 CECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED 441
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD--ECEDVDECG---DQRICDH 164
++ECS PC +C N+ G+++C C GY+L+ +D CED+DEC IC +
Sbjct: 442 INECS--SSPC--SQECANVYGSYQCYCRRGYQLS-DVDGVTCEDIDECALPTGGHICSY 496
Query: 165 GDCRNTIGSYRCEC-KPGYTLREN--VCRDVDECSRPRPVCR-NGTCENLPGAYLC---H 217
C N GS++C C GY L N C+D+DEC C N TC N+ GA+ C
Sbjct: 497 -RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFE 555
Query: 218 CDDGFKAGPNNDC 230
C + ++ C
Sbjct: 556 CPENYRRSAATRC 568
Score = 97.9 bits (233), Expect = 1e-19
Identities = 52/118 (44%), Positives = 63/118 (53%), Gaps = 15/118 (12%)
Query: 747 DVDECAAIPG-LCAP------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
DV+EC PG LC G + C C G+R + G C D++EC+ PC Q C N
Sbjct: 399 DVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECAN 456
Query: 798 TDGSYDCLCRTGYEL-DEDGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGY 851
GSY C CR GY+L D DG C D+DEC T H C C N GS++CSC GY
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGY 514
Score = 96.3 bits (229), Expect = 4e-19
Identities = 50/117 (42%), Positives = 61/117 (52%), Gaps = 13/117 (11%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAG--EVCADVDECAVRPPP-CDQLC 795
DVDECA C +PG FRC C GY G +C DV+EC P C C
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 415
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
NT GSY C C G+ L DG +C D++EC + C Q C+N GSY+C C GY+
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQ 470
Score = 81.4 bits (192), Expect = 1e-14
Identities = 43/122 (35%), Positives = 64/122 (52%), Gaps = 15/122 (12%)
Query: 747 DVDECAAIPGL--CAP--GRFRCVCGPGYRPA---GEVCADVDECAVRPPP--CDQLCHN 797
D++EC++ P CA G ++C C GY+ + G C D+DECA+ C C N
Sbjct: 441 DINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 798 TDGSYDCLC-RTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC---SCEDGY 851
GS+ C C +GY L +G NC+D+DEC H C + C N +G++ C C + Y
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENY 560
Query: 852 EK 853
+
Sbjct: 561 RR 562
Score = 75.4 bits (177), Expect = 8e-13
Identities = 47/127 (37%), Positives = 60/127 (47%), Gaps = 22/127 (17%)
Query: 747 DVDECAAIPGLCAP--------GRFRC----VCGPGY-RPAGEVCADVDECAVRPPPCD- 792
D+DEC + C P G FRC C G+ + A C D++EC PC
Sbjct: 262 DIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPI 321
Query: 793 -QLCHNTDGSYDCL-----CRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 844
C NT+GSY C C GY L+E+G C DVDEC C + C N+ GS+
Sbjct: 322 GHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 845 CSCEDGY 851
C C+ GY
Sbjct: 382 CECKTGY 388
Score = 72.1 bits (169), Expect = 8e-12
Identities = 42/101 (41%), Positives = 52/101 (51%), Gaps = 15/101 (14%)
Query: 765 CVCGPGYR--PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCL----CRTGYELDEDG 816
C C GY+ G C DV+EC C + C NT GS+ C C TGYEL ED
Sbjct: 199 CSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN 258
Query: 817 ANCRDVDECERDTHTC--QQICSNTEGSYEC----SCEDGY 851
+ C+D+DECE H C IC NT GS+ C C+ G+
Sbjct: 259 S-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 298
Score = 66.1 bits (154), Expect = 5e-10
Identities = 31/73 (42%), Positives = 40/73 (54%), Gaps = 6/73 (8%)
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 845
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 185 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 846 --SCEDGYEKRGD 856
SC GYE D
Sbjct: 245 DSSCGTGYELTED 257
Score = 62.1 bits (144), Expect = 8e-09
Identities = 51/161 (31%), Positives = 65/161 (40%), Gaps = 22/161 (13%)
Query: 21 YLCCCSVGHAW---GAPCEACPPRGSPAHTALCGEKPGEY---------INPVTNET-KP 67
YLC CSVG G CE S + C G Y ++ V T +
Sbjct: 422 YLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCED 481
Query: 68 IDECDIMP--QLCKPGTCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
IDEC + +C C + P FQC C GY C+D+DEC G C
Sbjct: 482 IDECALPTGGHICS-YRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 540
Query: 125 QCVNLPGAFEC---RCPPGYRLTPSLDECEDVDECGDQRIC 162
C N+ GAF C CP YR + + CE + C + R C
Sbjct: 541 TCFNIQGAFRCLAFECPENYRRS-AATRCERL-PCHENREC 579
>BC022497-1|AAH22497.1| 683|Homo sapiens fibulin 1 protein.
Length = 683
Score = 219 bits (535), Expect = 3e-56
Identities = 151/437 (34%), Positives = 207/437 (47%), Gaps = 61/437 (13%)
Query: 193 DECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGR-CRN 250
D C P C+ C + +C C G++ + C DVNEC G CR G C N
Sbjct: 178 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 251 TVGSFRCE----CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC---- 302
TVGSFRC+ C GY LT D +C+D+DEC+ H C D C NT G + C
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDF--ICQNTLGSFRCRPKL 292
Query: 303 SCGAGW--KLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCE-----CPAGWRFDKTA 354
C +G+ +G C+D +EC + C G C N G Y C+ C G+ ++
Sbjct: 293 QCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEG 351
Query: 355 AVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC 414
CVD E G+ HR C S G+ RC F
Sbjct: 352 TRCVDV-DECAPPAEPCGKGHR----------CVNSPGSF------RCECKTGYYF---- 390
Query: 415 QGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECAL 474
G+ R + D++EC+ P G +C NT GS+ C C G+ L+ DG SC D +EC+
Sbjct: 391 -DGISR--MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 475 DPRICGNGTCSNTRGGYECQCSPGF--TQGPDQTCVDVDECA--EGRASCTFRCHNTAGS 530
P C C+N G Y+C C G+ + TC D+DECA G C++RC N GS
Sbjct: 448 SP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 504
Query: 531 FRCTCP-YGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC---KCPEGYRRTS 584
F+C+CP GY +A +G +C+DIDECV C C N+ G + C +CPE YRR++
Sbjct: 505 FQCSCPSSGYRLAPNGSNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSA 564
Query: 585 APQDSENACEDINECEE 601
A + C + EC +
Sbjct: 565 ATRCERLPCHENRECSK 581
Score = 210 bits (512), Expect = 2e-53
Identities = 143/434 (32%), Positives = 194/434 (44%), Gaps = 61/434 (14%)
Query: 111 DECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GDQRICDHGD-CR 168
D C G P C+ QC + C C GY+L CEDV+EC C G+ C
Sbjct: 178 DRCRGGGP-CK--QQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCI 234
Query: 169 NTIGSYRCE----CKPGYTLRE-NVCRDVDECSRPRPVCR-NGTCENLPGAYLCH----C 218
NT+GS+RC+ C GY L E N C+D+DEC C + C+N G++ C C
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294
Query: 219 DDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCE-----CAPGYTLTADGRNC 272
GF +C+D+NEC C G C NT GS+ C+ C GY L +G C
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354
Query: 273 RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAG 330
DVDEC PCG+ C N+ G + C C G+ G R CVD +EC+ P G
Sbjct: 355 VDVDECAPPAEPCGKGHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCS 390
+C N G Y+C C G+R C D +E + C + C +
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDGRSCED------INECSSSPCSQE----------CAN 456
Query: 391 EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP--DVCVGGRCVNTDGS 448
++ YC R + + C +D+DEC + +C RC+N GS
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGV-TC----------EDIDECALPTGGHIC-SYRCINIPGS 504
Query: 449 FRCECP-DGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC---QCSPGFTQGP 503
F+C CP GY LAP+G +C D DEC C N TC N +GG+ C +C + +
Sbjct: 505 FQCSCPSSGYRLAPNGSNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSA 564
Query: 504 DQTCVDVDECAEGR 517
C + C E R
Sbjct: 565 ATRCERL-PCHENR 577
Score = 210 bits (512), Expect = 2e-53
Identities = 148/407 (36%), Positives = 200/407 (49%), Gaps = 53/407 (13%)
Query: 234 NECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+ CR GG C+ +CR+T C C GY L +DG +C DV+EC H C R G SC
Sbjct: 178 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC-RLGE-SC 233
Query: 294 TNTNGGYEC----SCGAGWKLV-GRRCVDRDECKELPYVCAGGE-CRNFNGGYVC----E 343
NT G + C SCG G++L C D DEC+ + C C+N G + C +
Sbjct: 234 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
C +G+ D C+D + L + P + C +EG+ C++
Sbjct: 294 CKSGFIQDALGN-CIDINECLSI----------SAPCPIGHT-CINTEGSYT---CQK-N 337
Query: 404 APDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPD 462
P+ + + G D+DEC + C G RCVN+ GSFRCEC GY D
Sbjct: 338 VPNCGRGYHLNEEG----TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF--D 391
Query: 463 GLS--CVDADECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRA 518
G+S CVD +EC P R+CG+ C NT G Y C CS GF D ++C D++EC+ +
Sbjct: 392 GISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS--S 448
Query: 519 SCTFRCHNTAGSFRCTCPYGYAVA-ADGVHCRDIDECVQEP--RVCPHACENVVGSYICK 575
C+ C N GS++C C GY ++ DGV C DIDEC +C + C N+ GS+ C
Sbjct: 449 PCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCS 508
Query: 576 CP-EGYRRTSAPQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
CP GYR AP S C+DI+EC CS C N G F C
Sbjct: 509 CPSSGYR--LAPNGSN--CQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 193 bits (470), Expect = 3e-48
Identities = 143/428 (33%), Positives = 183/428 (42%), Gaps = 59/428 (13%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECR- 136
CK C DT C C GY+ + C DV+EC G CR C+N G+F C+
Sbjct: 186 CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 137 ---CPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIGSYRC----ECKPGYTLRE- 186
C GY LT + C+D+DEC G C+NT+GS+RC +CK G+
Sbjct: 245 DSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 187 NVCRDVDECSRPRPVCRNG-TCENLPGAYLC-----HCDDGFKAGPNND-CVDVNECREG 239
C D++EC C G TC N G+Y C +C G+ CVDV+EC
Sbjct: 304 GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPP 363
Query: 240 GMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
C G RC N+ GSFRCEC GY R C DV+EC P GR C NT G
Sbjct: 364 AEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYP---GRLCGHKCENTLG 420
Query: 299 GYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
Y CSC G++L GR C D +EC P C+ EC N G Y C C G++ V
Sbjct: 421 SYLCSCSVGFRLSVDGRSCEDINECSSSP--CS-QECANVYGSYQCYCRRGYQLSDVDGV 477
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
++ E C + C G+ +C P S R+
Sbjct: 478 TCEDIDE----------CALPTGGHICSYRCINIPGSF------QCSCPSSG--YRLAPN 519
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRC---ECPDGY----VLAPDGLSCVD 468
G QD+DEC C + C N G FRC ECP+ Y + L C +
Sbjct: 520 GSN----CQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHE 575
Query: 469 ADECALDP 476
EC+ P
Sbjct: 576 NRECSKLP 583
Score = 176 bits (429), Expect = 2e-43
Identities = 127/374 (33%), Positives = 175/374 (46%), Gaps = 52/374 (13%)
Query: 287 RDGNP---SCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGE-CRNFNGGY 340
R G P C +T CSC G++L+ G C D +EC + C GE C N G +
Sbjct: 181 RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 240
Query: 341 VCE----CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWG 396
C+ C G+ + + C D DE E+G + P+ C G
Sbjct: 241 RCQRDSSCGTGYELTEDNS-CKD------IDECESG-------IHNCLPDFICQN--TLG 284
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCE--- 452
+ RC P Q +G D++EC C +G C+NT+GS+ C+
Sbjct: 285 SF--RC-RPKLQCKSGFIQDALGN---CIDINECLSISAPCPIGHTCINTEGSYTCQKNV 338
Query: 453 --CPDGYVLAPDGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFT-QGPDQTCV 508
C GY L +G CVD DECA CG G C N+ G + C+C G+ G + CV
Sbjct: 339 PNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV 398
Query: 509 DVDECAE--GRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
DV+EC GR C +C NT GS+ C+C G+ ++ DG C DI+EC P C C
Sbjct: 399 DVNECQRYPGRL-CGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQECA 455
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED--LCSGGVCINTDGSFLCDC-D 623
NV GSY C C GY+ + + CEDI+EC +CS CIN GSF C C
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVT---CEDIDECALPTGGHICSYR-CINIPGSFQCSCPS 511
Query: 624 AGFEPSEDGTDCID 637
+G+ + +G++C D
Sbjct: 512 SGYRLAPNGSNCQD 525
Score = 165 bits (400), Expect = 8e-40
Identities = 94/250 (37%), Positives = 127/250 (50%), Gaps = 22/250 (8%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQC-----GCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
I+EC + C G TC +T + C C GY + C DVDEC+ PC
Sbjct: 309 INECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCG 368
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG--DQRICDHGDCRNTIGSYRCECK 179
+CVN PG+F C C GY C DV+EC R+C H C NT+GSY C C
Sbjct: 369 KGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCS 427
Query: 180 PGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN--DCVDVNE 235
G+ L + C D++ECS P + C N+ G+Y C+C G++ + C D++E
Sbjct: 428 VGFRLSVDGRSCEDINECS-SSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDE 484
Query: 236 CR--EGGMVCRNGRCRNTVGSFRCEC-APGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
C GG +C + RC N GSF+C C + GY L +G NC+D+DEC H C N +
Sbjct: 485 CALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGSNCQDIDECVTGIHNCSI--NET 541
Query: 293 CTNTNGGYEC 302
C N GG+ C
Sbjct: 542 CFNIQGGFRC 551
Score = 151 bits (365), Expect = 1e-35
Identities = 91/247 (36%), Positives = 112/247 (45%), Gaps = 26/247 (10%)
Query: 425 QDLDECRVRPDVC-VGGRCVNTDGSFRCE----CPDGYVLAPDGLSCVDADECALDPRIC 479
+D++EC C +G C+NT GSFRC+ C GY L D SC D DEC C
Sbjct: 215 EDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNC 273
Query: 480 -GNGTCSNTRGGYEC----QCSPGFTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFR 532
+ C NT G + C QC GF Q C+D++EC A C C NT GS+
Sbjct: 274 LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 533 C-----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSA 585
C C GY + +G C D+DEC C H C N GS+ C+C GY
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 586 PQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYR 645
+ C D+NEC+ G C NT GS+LC C GF S DG C D C
Sbjct: 394 SR----MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED--INECSS 447
Query: 646 SLVSGRC 652
S S C
Sbjct: 448 SPCSQEC 454
Score = 136 bits (328), Expect = 4e-31
Identities = 90/266 (33%), Positives = 122/266 (45%), Gaps = 33/266 (12%)
Query: 416 GGMGRPNLTQDLDECRVRP---DVCVGG-----RCVNTDGSFRCECPDGYVLAPDGLSCV 467
GG+ + +++E + P D C GG +C +T C C GY L DG+SC
Sbjct: 156 GGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCE 215
Query: 468 DADECALDPRICGNG-TCSNTRGGYECQ----CSPGFTQGPDQTCVDVDECAEGRASC-- 520
D +EC C G +C NT G + CQ C G+ D +C D+DEC G +C
Sbjct: 216 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLP 275
Query: 521 TFRCHNTAGSFRC----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC 574
F C NT GSFRC C G+ A G +C DI+EC+ CP H C N GSY C
Sbjct: 276 DFICQNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTC 334
Query: 575 K-----CPEGYRRTSAPQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFEP 628
+ C GY + C D++EC + C G C+N+ GSF C+C G+
Sbjct: 335 QKNVPNCGRGYHL----NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 629 SEDGTDCIDRRTGTCYRSLVSG-RCE 653
C+D Y + G +CE
Sbjct: 391 DGISRMCVDVNECQRYPGRLCGHKCE 416
Score = 98.7 bits (235), Expect = 8e-20
Identities = 60/193 (31%), Positives = 89/193 (46%), Gaps = 18/193 (9%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C K G Y + ++ ++EC P C +T + C C G+ C D
Sbjct: 382 CECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED 441
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD--ECEDVDECG---DQRICDH 164
++ECS PC +C N+ G+++C C GY+L+ +D CED+DEC IC +
Sbjct: 442 INECS--SSPC--SQECANVYGSYQCYCRRGYQLS-DVDGVTCEDIDECALPTGGHICSY 496
Query: 165 GDCRNTIGSYRCEC-KPGYTLREN--VCRDVDECSRPRPVCR-NGTCENLPGAYLC---H 217
C N GS++C C GY L N C+D+DEC C N TC N+ G + C
Sbjct: 497 -RCINIPGSFQCSCPSSGYRLAPNGSNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFE 555
Query: 218 CDDGFKAGPNNDC 230
C + ++ C
Sbjct: 556 CPENYRRSAATRC 568
Score = 97.9 bits (233), Expect = 1e-19
Identities = 52/118 (44%), Positives = 63/118 (53%), Gaps = 15/118 (12%)
Query: 747 DVDECAAIPG-LCAP------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
DV+EC PG LC G + C C G+R + G C D++EC+ PC Q C N
Sbjct: 399 DVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECAN 456
Query: 798 TDGSYDCLCRTGYEL-DEDGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGY 851
GSY C CR GY+L D DG C D+DEC T H C C N GS++CSC GY
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGY 514
Score = 96.3 bits (229), Expect = 4e-19
Identities = 50/117 (42%), Positives = 61/117 (52%), Gaps = 13/117 (11%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAG--EVCADVDECAVRPPP-CDQLC 795
DVDECA C +PG FRC C GY G +C DV+EC P C C
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 415
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
NT GSY C C G+ L DG +C D++EC + C Q C+N GSY+C C GY+
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQ 470
Score = 81.8 bits (193), Expect = 9e-15
Identities = 43/122 (35%), Positives = 64/122 (52%), Gaps = 15/122 (12%)
Query: 747 DVDECAAIPGL--CAP--GRFRCVCGPGYRPA---GEVCADVDECAVRPPP--CDQLCHN 797
D++EC++ P CA G ++C C GY+ + G C D+DECA+ C C N
Sbjct: 441 DINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 798 TDGSYDCLC-RTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC---SCEDGY 851
GS+ C C +GY L +G+NC+D+DEC H C + C N +G + C C + Y
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGSNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Query: 852 EK 853
+
Sbjct: 561 RR 562
Score = 75.4 bits (177), Expect = 8e-13
Identities = 47/127 (37%), Positives = 60/127 (47%), Gaps = 22/127 (17%)
Query: 747 DVDECAAIPGLCAP--------GRFRC----VCGPGY-RPAGEVCADVDECAVRPPPCD- 792
D+DEC + C P G FRC C G+ + A C D++EC PC
Sbjct: 262 DIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPI 321
Query: 793 -QLCHNTDGSYDCL-----CRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 844
C NT+GSY C C GY L+E+G C DVDEC C + C N+ GS+
Sbjct: 322 GHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 845 CSCEDGY 851
C C+ GY
Sbjct: 382 CECKTGY 388
Score = 72.1 bits (169), Expect = 8e-12
Identities = 42/101 (41%), Positives = 52/101 (51%), Gaps = 15/101 (14%)
Query: 765 CVCGPGYR--PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCL----CRTGYELDEDG 816
C C GY+ G C DV+EC C + C NT GS+ C C TGYEL ED
Sbjct: 199 CSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN 258
Query: 817 ANCRDVDECERDTHTC--QQICSNTEGSYEC----SCEDGY 851
+ C+D+DECE H C IC NT GS+ C C+ G+
Sbjct: 259 S-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 298
Score = 66.1 bits (154), Expect = 5e-10
Identities = 31/73 (42%), Positives = 40/73 (54%), Gaps = 6/73 (8%)
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 845
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 185 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 846 --SCEDGYEKRGD 856
SC GYE D
Sbjct: 245 DSSCGTGYELTED 257
Score = 60.1 bits (139), Expect = 3e-08
Identities = 50/161 (31%), Positives = 64/161 (39%), Gaps = 22/161 (13%)
Query: 21 YLCCCSVGHAW---GAPCEACPPRGSPAHTALCGEKPGEY---------INPVTNET-KP 67
YLC CSVG G CE S + C G Y ++ V T +
Sbjct: 422 YLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCED 481
Query: 68 IDECDIMP--QLCKPGTCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
IDEC + +C C + P FQC C GY C+D+DEC G C
Sbjct: 482 IDECALPTGGHICS-YRCINIPGSFQCSCPSSGYRLAPNGSNCQDIDECVTGIHNCSINE 540
Query: 125 QCVNLPGAFEC---RCPPGYRLTPSLDECEDVDECGDQRIC 162
C N+ G F C CP YR + + CE + C + R C
Sbjct: 541 TCFNIQGGFRCLAFECPENYRRS-AATRCERL-PCHENREC 579
>AF217999-1|AAG17241.1| 495|Homo sapiens unknown protein.
Length = 495
Score = 219 bits (534), Expect = 5e-56
Identities = 151/437 (34%), Positives = 207/437 (47%), Gaps = 61/437 (13%)
Query: 193 DECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGR-CRN 250
D C P C+ C + +C C G++ + C DVNEC G CR G C N
Sbjct: 48 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 105
Query: 251 TVGSFRCE----CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC---- 302
TVGSFRC+ C GY LT D +C+D+DEC+ H C D C NT G + C
Sbjct: 106 TVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDF--ICQNTLGSFRCRPKL 162
Query: 303 SCGAGW--KLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCE-----CPAGWRFDKTA 354
C +G+ +G C+D +EC + C G C N G Y C+ C G+ ++
Sbjct: 163 QCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEG 221
Query: 355 AVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC 414
CVD E G+ HR C S G+ RC F
Sbjct: 222 TRCVDV-DECAPPAEPCGKGHR----------CVNSPGSF------RCECKTGYYF---- 260
Query: 415 QGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECAL 474
G+ R + D++EC+ P G +C NT GS+ C C G+ L+ DG SC D +EC+
Sbjct: 261 -DGISR--MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 317
Query: 475 DPRICGNGTCSNTRGGYECQCSPGF--TQGPDQTCVDVDECA--EGRASCTFRCHNTAGS 530
P C C+N G Y+C C G+ + TC D+DECA G C++RC N GS
Sbjct: 318 SP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 374
Query: 531 FRCTCP-YGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC---KCPEGYRRTS 584
F+C+CP GY +A +G +C+DIDECV C C N+ G + C +CPE YRR++
Sbjct: 375 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSA 434
Query: 585 APQDSENACEDINECEE 601
A + C + EC +
Sbjct: 435 ATRCERLPCHENRECSK 451
Score = 210 bits (512), Expect = 2e-53
Identities = 143/434 (32%), Positives = 194/434 (44%), Gaps = 61/434 (14%)
Query: 111 DECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GDQRICDHGD-CR 168
D C G P C+ QC + C C GY+L CEDV+EC C G+ C
Sbjct: 48 DRCRGGGP-CK--QQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCI 104
Query: 169 NTIGSYRCE----CKPGYTLRE-NVCRDVDECSRPRPVCR-NGTCENLPGAYLCH----C 218
NT+GS+RC+ C GY L E N C+D+DEC C + C+N G++ C C
Sbjct: 105 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 164
Query: 219 DDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCE-----CAPGYTLTADGRNC 272
GF +C+D+NEC C G C NT GS+ C+ C GY L +G C
Sbjct: 165 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 224
Query: 273 RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAG 330
DVDEC PCG+ C N+ G + C C G+ G R CVD +EC+ P G
Sbjct: 225 VDVDECAPPAEPCGKGHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 282
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCS 390
+C N G Y+C C G+R C D +E + C + C +
Sbjct: 283 HKCENTLGSYLCSCSVGFRLSVDGRSCED------INECSSSPCSQE----------CAN 326
Query: 391 EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP--DVCVGGRCVNTDGS 448
++ YC R + + C +D+DEC + +C RC+N GS
Sbjct: 327 VYGSYQCYCRRGYQLSDVDGV-TC----------EDIDECALPTGGHIC-SYRCINIPGS 374
Query: 449 FRCECP-DGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC---QCSPGFTQGP 503
F+C CP GY LAP+G +C D DEC C N TC N +GG+ C +C + +
Sbjct: 375 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSA 434
Query: 504 DQTCVDVDECAEGR 517
C + C E R
Sbjct: 435 ATRCERL-PCHENR 447
Score = 208 bits (507), Expect = 8e-53
Identities = 147/407 (36%), Positives = 199/407 (48%), Gaps = 53/407 (13%)
Query: 234 NECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+ CR GG C+ +CR+T C C GY L +DG +C DV+EC H C R G SC
Sbjct: 48 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC-RLGE-SC 103
Query: 294 TNTNGGYEC----SCGAGWKLV-GRRCVDRDECKELPYVCAGGE-CRNFNGGYVC----E 343
NT G + C SCG G++L C D DEC+ + C C+N G + C +
Sbjct: 104 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 163
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
C +G+ D C+D + L + P + C +EG+ C++
Sbjct: 164 CKSGFIQDALGN-CIDINECLSI----------SAPCPIGHT-CINTEGSYT---CQK-N 207
Query: 404 APDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPD 462
P+ + + G D+DEC + C G RCVN+ GSFRCEC GY D
Sbjct: 208 VPNCGRGYHLNEEG----TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF--D 261
Query: 463 GLS--CVDADECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRA 518
G+S CVD +EC P R+CG+ C NT G Y C CS GF D ++C D++EC+ +
Sbjct: 262 GISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS--S 318
Query: 519 SCTFRCHNTAGSFRCTCPYGYAVA-ADGVHCRDIDECVQEP--RVCPHACENVVGSYICK 575
C+ C N GS++C C GY ++ DGV C DIDEC +C + C N+ GS+ C
Sbjct: 319 PCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCS 378
Query: 576 CP-EGYRRTSAPQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
CP GYR AP C+DI+EC CS C N G F C
Sbjct: 379 CPSSGYR--LAPNGRN--CQDIDECVTGIHNCSINETCFNIQGGFRC 421
Score = 193 bits (470), Expect = 3e-48
Identities = 143/428 (33%), Positives = 183/428 (42%), Gaps = 59/428 (13%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECR- 136
CK C DT C C GY+ + C DV+EC G CR C+N G+F C+
Sbjct: 56 CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 114
Query: 137 ---CPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIGSYRC----ECKPGYTLRE- 186
C GY LT + C+D+DEC G C+NT+GS+RC +CK G+
Sbjct: 115 DSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 173
Query: 187 NVCRDVDECSRPRPVCRNG-TCENLPGAYLC-----HCDDGFKAGPNND-CVDVNECREG 239
C D++EC C G TC N G+Y C +C G+ CVDV+EC
Sbjct: 174 GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPP 233
Query: 240 GMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
C G RC N+ GSFRCEC GY R C DV+EC P GR C NT G
Sbjct: 234 AEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYP---GRLCGHKCENTLG 290
Query: 299 GYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
Y CSC G++L GR C D +EC P C+ EC N G Y C C G++ V
Sbjct: 291 SYLCSCSVGFRLSVDGRSCEDINECSSSP--CS-QECANVYGSYQCYCRRGYQLSDVDGV 347
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
++ E C + C G+ +C P S R+
Sbjct: 348 TCEDIDE----------CALPTGGHICSYRCINIPGSF------QCSCPSSG--YRLAPN 389
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRC---ECPDGY----VLAPDGLSCVD 468
G QD+DEC C + C N G FRC ECP+ Y + L C +
Sbjct: 390 GRN----CQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHE 445
Query: 469 ADECALDP 476
EC+ P
Sbjct: 446 NRECSKLP 453
Score = 175 bits (427), Expect = 4e-43
Identities = 127/374 (33%), Positives = 174/374 (46%), Gaps = 52/374 (13%)
Query: 287 RDGNP---SCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGE-CRNFNGGY 340
R G P C +T CSC G++L+ G C D +EC + C GE C N G +
Sbjct: 51 RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 110
Query: 341 VCE----CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWG 396
C+ C G+ + + C D DE E+G + P+ C G
Sbjct: 111 RCQRDSSCGTGYELTEDNS-CKD------IDECESG-------IHNCLPDFICQN--TLG 154
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCE--- 452
+ RC P Q +G D++EC C +G C+NT+GS+ C+
Sbjct: 155 SF--RC-RPKLQCKSGFIQDALGN---CIDINECLSISAPCPIGHTCINTEGSYTCQKNV 208
Query: 453 --CPDGYVLAPDGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFT-QGPDQTCV 508
C GY L +G CVD DECA CG G C N+ G + C+C G+ G + CV
Sbjct: 209 PNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV 268
Query: 509 DVDECAE--GRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
DV+EC GR C +C NT GS+ C+C G+ ++ DG C DI+EC P C C
Sbjct: 269 DVNECQRYPGRL-CGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQECA 325
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED--LCSGGVCINTDGSFLCDC-D 623
NV GSY C C GY+ + + CEDI+EC +CS CIN GSF C C
Sbjct: 326 NVYGSYQCYCRRGYQLSDVDGVT---CEDIDECALPTGGHICSYR-CINIPGSFQCSCPS 381
Query: 624 AGFEPSEDGTDCID 637
+G+ + +G +C D
Sbjct: 382 SGYRLAPNGRNCQD 395
Score = 167 bits (406), Expect = 1e-40
Identities = 95/250 (38%), Positives = 128/250 (51%), Gaps = 22/250 (8%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQC-----GCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
I+EC + C G TC +T + C C GY + C DVDEC+ PC
Sbjct: 179 INECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCG 238
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG--DQRICDHGDCRNTIGSYRCECK 179
+CVN PG+F C C GY C DV+EC R+C H C NT+GSY C C
Sbjct: 239 KGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCS 297
Query: 180 PGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN--DCVDVNE 235
G+ L + C D++ECS P + C N+ G+Y C+C G++ + C D++E
Sbjct: 298 VGFRLSVDGRSCEDINECS-SSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDE 354
Query: 236 CR--EGGMVCRNGRCRNTVGSFRCEC-APGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
C GG +C + RC N GSF+C C + GY L +GRNC+D+DEC H C N +
Sbjct: 355 CALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI--NET 411
Query: 293 CTNTNGGYEC 302
C N GG+ C
Sbjct: 412 CFNIQGGFRC 421
Score = 151 bits (365), Expect = 1e-35
Identities = 91/247 (36%), Positives = 112/247 (45%), Gaps = 26/247 (10%)
Query: 425 QDLDECRVRPDVC-VGGRCVNTDGSFRCE----CPDGYVLAPDGLSCVDADECALDPRIC 479
+D++EC C +G C+NT GSFRC+ C GY L D SC D DEC C
Sbjct: 85 EDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNC 143
Query: 480 -GNGTCSNTRGGYEC----QCSPGFTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFR 532
+ C NT G + C QC GF Q C+D++EC A C C NT GS+
Sbjct: 144 LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYT 203
Query: 533 C-----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSA 585
C C GY + +G C D+DEC C H C N GS+ C+C GY
Sbjct: 204 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 263
Query: 586 PQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYR 645
+ C D+NEC+ G C NT GS+LC C GF S DG C D C
Sbjct: 264 SR----MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED--INECSS 317
Query: 646 SLVSGRC 652
S S C
Sbjct: 318 SPCSQEC 324
Score = 136 bits (328), Expect = 4e-31
Identities = 90/266 (33%), Positives = 122/266 (45%), Gaps = 33/266 (12%)
Query: 416 GGMGRPNLTQDLDECRVRP---DVCVGG-----RCVNTDGSFRCECPDGYVLAPDGLSCV 467
GG+ + +++E + P D C GG +C +T C C GY L DG+SC
Sbjct: 26 GGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCE 85
Query: 468 DADECALDPRICGNG-TCSNTRGGYECQ----CSPGFTQGPDQTCVDVDECAEGRASC-- 520
D +EC C G +C NT G + CQ C G+ D +C D+DEC G +C
Sbjct: 86 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLP 145
Query: 521 TFRCHNTAGSFRC----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC 574
F C NT GSFRC C G+ A G +C DI+EC+ CP H C N GSY C
Sbjct: 146 DFICQNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTC 204
Query: 575 K-----CPEGYRRTSAPQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFEP 628
+ C GY + C D++EC + C G C+N+ GSF C+C G+
Sbjct: 205 QKNVPNCGRGYHL----NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 260
Query: 629 SEDGTDCIDRRTGTCYRSLVSG-RCE 653
C+D Y + G +CE
Sbjct: 261 DGISRMCVDVNECQRYPGRLCGHKCE 286
Score = 98.7 bits (235), Expect = 8e-20
Identities = 60/193 (31%), Positives = 89/193 (46%), Gaps = 18/193 (9%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C K G Y + ++ ++EC P C +T + C C G+ C D
Sbjct: 252 CECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED 311
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD--ECEDVDECG---DQRICDH 164
++ECS PC +C N+ G+++C C GY+L+ +D CED+DEC IC +
Sbjct: 312 INECS--SSPC--SQECANVYGSYQCYCRRGYQLS-DVDGVTCEDIDECALPTGGHICSY 366
Query: 165 GDCRNTIGSYRCEC-KPGYTLREN--VCRDVDECSRPRPVCR-NGTCENLPGAYLC---H 217
C N GS++C C GY L N C+D+DEC C N TC N+ G + C
Sbjct: 367 -RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFE 425
Query: 218 CDDGFKAGPNNDC 230
C + ++ C
Sbjct: 426 CPENYRRSAATRC 438
Score = 97.9 bits (233), Expect = 1e-19
Identities = 52/118 (44%), Positives = 63/118 (53%), Gaps = 15/118 (12%)
Query: 747 DVDECAAIPG-LCAP------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
DV+EC PG LC G + C C G+R + G C D++EC+ PC Q C N
Sbjct: 269 DVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECAN 326
Query: 798 TDGSYDCLCRTGYEL-DEDGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGY 851
GSY C CR GY+L D DG C D+DEC T H C C N GS++CSC GY
Sbjct: 327 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGY 384
Score = 96.3 bits (229), Expect = 4e-19
Identities = 50/117 (42%), Positives = 61/117 (52%), Gaps = 13/117 (11%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAG--EVCADVDECAVRPPP-CDQLC 795
DVDECA C +PG FRC C GY G +C DV+EC P C C
Sbjct: 226 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 285
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
NT GSY C C G+ L DG +C D++EC + C Q C+N GSY+C C GY+
Sbjct: 286 ENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQ 340
Score = 81.0 bits (191), Expect = 2e-14
Identities = 43/122 (35%), Positives = 63/122 (51%), Gaps = 15/122 (12%)
Query: 747 DVDECAAIPGL--CAP--GRFRCVCGPGYRPA---GEVCADVDECAVRPPP--CDQLCHN 797
D++EC++ P CA G ++C C GY+ + G C D+DECA+ C C N
Sbjct: 311 DINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 370
Query: 798 TDGSYDCLC-RTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC---SCEDGY 851
GS+ C C +GY L +G NC+D+DEC H C + C N +G + C C + Y
Sbjct: 371 IPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 430
Query: 852 EK 853
+
Sbjct: 431 RR 432
Score = 75.4 bits (177), Expect = 8e-13
Identities = 47/127 (37%), Positives = 60/127 (47%), Gaps = 22/127 (17%)
Query: 747 DVDECAAIPGLCAP--------GRFRC----VCGPGY-RPAGEVCADVDECAVRPPPCD- 792
D+DEC + C P G FRC C G+ + A C D++EC PC
Sbjct: 132 DIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPI 191
Query: 793 -QLCHNTDGSYDCL-----CRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 844
C NT+GSY C C GY L+E+G C DVDEC C + C N+ GS+
Sbjct: 192 GHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 251
Query: 845 CSCEDGY 851
C C+ GY
Sbjct: 252 CECKTGY 258
Score = 72.1 bits (169), Expect = 8e-12
Identities = 42/101 (41%), Positives = 52/101 (51%), Gaps = 15/101 (14%)
Query: 765 CVCGPGYR--PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCL----CRTGYELDEDG 816
C C GY+ G C DV+EC C + C NT GS+ C C TGYEL ED
Sbjct: 69 CSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN 128
Query: 817 ANCRDVDECERDTHTC--QQICSNTEGSYEC----SCEDGY 851
+ C+D+DECE H C IC NT GS+ C C+ G+
Sbjct: 129 S-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 168
Score = 66.1 bits (154), Expect = 5e-10
Identities = 31/73 (42%), Positives = 40/73 (54%), Gaps = 6/73 (8%)
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 845
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 55 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 114
Query: 846 --SCEDGYEKRGD 856
SC GYE D
Sbjct: 115 DSSCGTGYELTED 127
Score = 60.5 bits (140), Expect = 2e-08
Identities = 50/161 (31%), Positives = 64/161 (39%), Gaps = 22/161 (13%)
Query: 21 YLCCCSVGHAW---GAPCEACPPRGSPAHTALCGEKPGEY---------INPVTNET-KP 67
YLC CSVG G CE S + C G Y ++ V T +
Sbjct: 292 YLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCED 351
Query: 68 IDECDIMP--QLCKPGTCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
IDEC + +C C + P FQC C GY C+D+DEC G C
Sbjct: 352 IDECALPTGGHICS-YRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 410
Query: 125 QCVNLPGAFEC---RCPPGYRLTPSLDECEDVDECGDQRIC 162
C N+ G F C CP YR + + CE + C + R C
Sbjct: 411 TCFNIQGGFRCLAFECPENYRRS-AATRCERL-PCHENREC 449
>X53742-1|CAA37771.1| 601|Homo sapiens fibulin-1 B protein.
Length = 601
Score = 218 bits (532), Expect = 8e-56
Identities = 152/440 (34%), Positives = 210/440 (47%), Gaps = 61/440 (13%)
Query: 193 DECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGR-CRN 250
D C P C+ C + +C C G++ + C DVNEC G CR G C N
Sbjct: 178 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 251 TVGSFRCE----CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC---- 302
TVGSFRC+ C GY LT D +C+D+DEC+ H C D C NT G + C
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDF--ICQNTLGSFRCRPKL 292
Query: 303 SCGAGW--KLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCE-----CPAGWRFDKTA 354
C +G+ +G C+D +EC + C G C N G Y C+ C G+ ++
Sbjct: 293 QCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEG 351
Query: 355 AVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC 414
CVD E G+ HR C S G+ RC F
Sbjct: 352 TRCVDV-DECAPPAEPCGKGHR----------CVNSPGSF------RCECKTGYYF---- 390
Query: 415 QGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECAL 474
G+ R + D++EC+ P G +C NT GS+ C C G+ L+ DG SC D +EC+
Sbjct: 391 -DGISR--MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 475 DPRICGNGTCSNTRGGYECQCSPGF--TQGPDQTCVDVDECA--EGRASCTFRCHNTAGS 530
P C C+N G Y+C C G+ + TC D+DECA G C++RC N GS
Sbjct: 448 SP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 504
Query: 531 FRCTCP-YGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC---KCPEGYRRTS 584
F+C+CP GY +A +G +C+DIDECV C C N+ G++ C +CPE YRR++
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENYRRSA 564
Query: 585 APQDSENACEDINECEEQED 604
A Q S+ ++ +ED
Sbjct: 565 ATQKSKKGRQNTPAGSSKED 584
Score = 208 bits (508), Expect = 6e-53
Identities = 147/407 (36%), Positives = 200/407 (49%), Gaps = 53/407 (13%)
Query: 234 NECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+ CR GG C+ +CR+T C C GY L +DG +C DV+EC H C R G SC
Sbjct: 178 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC-RLGE-SC 233
Query: 294 TNTNGGYEC----SCGAGWKLV-GRRCVDRDECKELPYVCAGGE-CRNFNGGYVC----E 343
NT G + C SCG G++L C D DEC+ + C C+N G + C +
Sbjct: 234 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
C +G+ D C+D + L + P + C +EG+ C++
Sbjct: 294 CKSGFIQDALGN-CIDINECLSI----------SAPCPIGHT-CINTEGSYT---CQK-N 337
Query: 404 APDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPD 462
P+ + + G D+DEC + C G RCVN+ GSFRCEC GY D
Sbjct: 338 VPNCGRGYHLNEEG----TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF--D 391
Query: 463 GLS--CVDADECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRA 518
G+S CVD +EC P R+CG+ C NT G Y C CS GF D ++C D++EC+ +
Sbjct: 392 GISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS--S 448
Query: 519 SCTFRCHNTAGSFRCTCPYGYAVA-ADGVHCRDIDECVQEP--RVCPHACENVVGSYICK 575
C+ C N GS++C C GY ++ DGV C DIDEC +C + C N+ GS+ C
Sbjct: 449 PCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCS 508
Query: 576 CP-EGYRRTSAPQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
CP GYR AP C+DI+EC CS C N G+F C
Sbjct: 509 CPSSGYR--LAPNGRN--CQDIDECVTGIHNCSINETCFNIQGAFRC 551
Score = 206 bits (503), Expect = 3e-52
Identities = 137/407 (33%), Positives = 184/407 (45%), Gaps = 57/407 (14%)
Query: 111 DECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GDQRICDHGD-CR 168
D C G P C+ QC + C C GY+L CEDV+EC C G+ C
Sbjct: 178 DRCRGGGP-CK--QQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCI 234
Query: 169 NTIGSYRCE----CKPGYTLRE-NVCRDVDECSRPRPVCR-NGTCENLPGAYLCH----C 218
NT+GS+RC+ C GY L E N C+D+DEC C + C+N G++ C C
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294
Query: 219 DDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCE-----CAPGYTLTADGRNC 272
GF +C+D+NEC C G C NT GS+ C+ C GY L +G C
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354
Query: 273 RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAG 330
DVDEC PCG+ C N+ G + C C G+ G R CVD +EC+ P G
Sbjct: 355 VDVDECAPPAEPCGKGHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCS 390
+C N G Y+C C G+R C D +E + C + C +
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDGRSCED------INECSSSPCSQE----------CAN 456
Query: 391 EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP--DVCVGGRCVNTDGS 448
++ YC R + + C +D+DEC + +C RC+N GS
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGV-TC----------EDIDECALPTGGHIC-SYRCINIPGS 504
Query: 449 FRCECP-DGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
F+C CP GY LAP+G +C D DEC C N TC N +G + C
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRC 551
Score = 193 bits (470), Expect = 3e-48
Identities = 138/405 (34%), Positives = 176/405 (43%), Gaps = 55/405 (13%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECR- 136
CK C DT C C GY+ + C DV+EC G CR C+N G+F C+
Sbjct: 186 CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 137 ---CPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIGSYRC----ECKPGYTLRE- 186
C GY LT + C+D+DEC G C+NT+GS+RC +CK G+
Sbjct: 245 DSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 187 NVCRDVDECSRPRPVCRNG-TCENLPGAYLC-----HCDDGFKAGPNND-CVDVNECREG 239
C D++EC C G TC N G+Y C +C G+ CVDV+EC
Sbjct: 304 GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPP 363
Query: 240 GMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
C G RC N+ GSFRCEC GY R C DV+EC P GR C NT G
Sbjct: 364 AEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYP---GRLCGHKCENTLG 420
Query: 299 GYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
Y CSC G++L GR C D +EC P C+ EC N G Y C C G++ V
Sbjct: 421 SYLCSCSVGFRLSVDGRSCEDINECSSSP--CS-QECANVYGSYQCYCRRGYQLSDVDGV 477
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
++ E C + C G+ +C P S R+
Sbjct: 478 TCEDIDE----------CALPTGGHICSYRCINIPGSF------QCSCPSSG--YRLAPN 519
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRC---ECPDGY 457
G QD+DEC C + C N G+FRC ECP+ Y
Sbjct: 520 GRN----CQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENY 560
Score = 175 bits (427), Expect = 4e-43
Identities = 127/374 (33%), Positives = 174/374 (46%), Gaps = 52/374 (13%)
Query: 287 RDGNP---SCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGE-CRNFNGGY 340
R G P C +T CSC G++L+ G C D +EC + C GE C N G +
Sbjct: 181 RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 240
Query: 341 VCE----CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWG 396
C+ C G+ + + C D DE E+G + P+ C G
Sbjct: 241 RCQRDSSCGTGYELTEDNS-CKD------IDECESG-------IHNCLPDFICQN--TLG 284
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCE--- 452
+ RC P Q +G D++EC C +G C+NT+GS+ C+
Sbjct: 285 SF--RC-RPKLQCKSGFIQDALGN---CIDINECLSISAPCPIGHTCINTEGSYTCQKNV 338
Query: 453 --CPDGYVLAPDGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFT-QGPDQTCV 508
C GY L +G CVD DECA CG G C N+ G + C+C G+ G + CV
Sbjct: 339 PNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV 398
Query: 509 DVDECAE--GRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
DV+EC GR C +C NT GS+ C+C G+ ++ DG C DI+EC P C C
Sbjct: 399 DVNECQRYPGRL-CGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQECA 455
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED--LCSGGVCINTDGSFLCDC-D 623
NV GSY C C GY+ + + CEDI+EC +CS CIN GSF C C
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVT---CEDIDECALPTGGHICSYR-CINIPGSFQCSCPS 511
Query: 624 AGFEPSEDGTDCID 637
+G+ + +G +C D
Sbjct: 512 SGYRLAPNGRNCQD 525
Score = 165 bits (400), Expect = 8e-40
Identities = 94/250 (37%), Positives = 127/250 (50%), Gaps = 22/250 (8%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQC-----GCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
I+EC + C G TC +T + C C GY + C DVDEC+ PC
Sbjct: 309 INECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCG 368
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG--DQRICDHGDCRNTIGSYRCECK 179
+CVN PG+F C C GY C DV+EC R+C H C NT+GSY C C
Sbjct: 369 KGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCS 427
Query: 180 PGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN--DCVDVNE 235
G+ L + C D++ECS P + C N+ G+Y C+C G++ + C D++E
Sbjct: 428 VGFRLSVDGRSCEDINECS-SSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDE 484
Query: 236 CR--EGGMVCRNGRCRNTVGSFRCEC-APGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
C GG +C + RC N GSF+C C + GY L +GRNC+D+DEC H C N +
Sbjct: 485 CALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI--NET 541
Query: 293 CTNTNGGYEC 302
C N G + C
Sbjct: 542 CFNIQGAFRC 551
Score = 151 bits (365), Expect = 1e-35
Identities = 91/247 (36%), Positives = 112/247 (45%), Gaps = 26/247 (10%)
Query: 425 QDLDECRVRPDVC-VGGRCVNTDGSFRCE----CPDGYVLAPDGLSCVDADECALDPRIC 479
+D++EC C +G C+NT GSFRC+ C GY L D SC D DEC C
Sbjct: 215 EDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNC 273
Query: 480 -GNGTCSNTRGGYEC----QCSPGFTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFR 532
+ C NT G + C QC GF Q C+D++EC A C C NT GS+
Sbjct: 274 LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 533 C-----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSA 585
C C GY + +G C D+DEC C H C N GS+ C+C GY
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 586 PQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYR 645
+ C D+NEC+ G C NT GS+LC C GF S DG C D C
Sbjct: 394 SR----MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED--INECSS 447
Query: 646 SLVSGRC 652
S S C
Sbjct: 448 SPCSQEC 454
Score = 136 bits (328), Expect = 4e-31
Identities = 90/266 (33%), Positives = 122/266 (45%), Gaps = 33/266 (12%)
Query: 416 GGMGRPNLTQDLDECRVRP---DVCVGG-----RCVNTDGSFRCECPDGYVLAPDGLSCV 467
GG+ + +++E + P D C GG +C +T C C GY L DG+SC
Sbjct: 156 GGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCE 215
Query: 468 DADECALDPRICGNG-TCSNTRGGYECQ----CSPGFTQGPDQTCVDVDECAEGRASC-- 520
D +EC C G +C NT G + CQ C G+ D +C D+DEC G +C
Sbjct: 216 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLP 275
Query: 521 TFRCHNTAGSFRC----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC 574
F C NT GSFRC C G+ A G +C DI+EC+ CP H C N GSY C
Sbjct: 276 DFICQNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTC 334
Query: 575 K-----CPEGYRRTSAPQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFEP 628
+ C GY + C D++EC + C G C+N+ GSF C+C G+
Sbjct: 335 QKNVPNCGRGYHL----NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 629 SEDGTDCIDRRTGTCYRSLVSG-RCE 653
C+D Y + G +CE
Sbjct: 391 DGISRMCVDVNECQRYPGRLCGHKCE 416
Score = 99.1 bits (236), Expect = 6e-20
Identities = 59/176 (33%), Positives = 85/176 (48%), Gaps = 15/176 (8%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C K G Y + ++ ++EC P C +T + C C G+ C D
Sbjct: 382 CECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED 441
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD--ECEDVDECG---DQRICDH 164
++ECS PC +C N+ G+++C C GY+L+ +D CED+DEC IC +
Sbjct: 442 INECS--SSPC--SQECANVYGSYQCYCRRGYQLS-DVDGVTCEDIDECALPTGGHICSY 496
Query: 165 GDCRNTIGSYRCEC-KPGYTLREN--VCRDVDECSRPRPVCR-NGTCENLPGAYLC 216
C N GS++C C GY L N C+D+DEC C N TC N+ GA+ C
Sbjct: 497 -RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRC 551
Score = 97.9 bits (233), Expect = 1e-19
Identities = 52/118 (44%), Positives = 63/118 (53%), Gaps = 15/118 (12%)
Query: 747 DVDECAAIPG-LCAP------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
DV+EC PG LC G + C C G+R + G C D++EC+ PC Q C N
Sbjct: 399 DVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECAN 456
Query: 798 TDGSYDCLCRTGYEL-DEDGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGY 851
GSY C CR GY+L D DG C D+DEC T H C C N GS++CSC GY
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGY 514
Score = 96.3 bits (229), Expect = 4e-19
Identities = 50/117 (42%), Positives = 61/117 (52%), Gaps = 13/117 (11%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAG--EVCADVDECAVRPPP-CDQLC 795
DVDECA C +PG FRC C GY G +C DV+EC P C C
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 415
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
NT GSY C C G+ L DG +C D++EC + C Q C+N GSY+C C GY+
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQ 470
Score = 81.4 bits (192), Expect = 1e-14
Identities = 43/122 (35%), Positives = 64/122 (52%), Gaps = 15/122 (12%)
Query: 747 DVDECAAIPGL--CAP--GRFRCVCGPGYRPA---GEVCADVDECAVRPPP--CDQLCHN 797
D++EC++ P CA G ++C C GY+ + G C D+DECA+ C C N
Sbjct: 441 DINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 798 TDGSYDCLC-RTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC---SCEDGY 851
GS+ C C +GY L +G NC+D+DEC H C + C N +G++ C C + Y
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENY 560
Query: 852 EK 853
+
Sbjct: 561 RR 562
Score = 75.4 bits (177), Expect = 8e-13
Identities = 47/127 (37%), Positives = 60/127 (47%), Gaps = 22/127 (17%)
Query: 747 DVDECAAIPGLCAP--------GRFRC----VCGPGY-RPAGEVCADVDECAVRPPPCD- 792
D+DEC + C P G FRC C G+ + A C D++EC PC
Sbjct: 262 DIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPI 321
Query: 793 -QLCHNTDGSYDCL-----CRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 844
C NT+GSY C C GY L+E+G C DVDEC C + C N+ GS+
Sbjct: 322 GHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 845 CSCEDGY 851
C C+ GY
Sbjct: 382 CECKTGY 388
Score = 72.1 bits (169), Expect = 8e-12
Identities = 42/101 (41%), Positives = 52/101 (51%), Gaps = 15/101 (14%)
Query: 765 CVCGPGYR--PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCL----CRTGYELDEDG 816
C C GY+ G C DV+EC C + C NT GS+ C C TGYEL ED
Sbjct: 199 CSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN 258
Query: 817 ANCRDVDECERDTHTC--QQICSNTEGSYEC----SCEDGY 851
+ C+D+DECE H C IC NT GS+ C C+ G+
Sbjct: 259 S-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 298
Score = 66.1 bits (154), Expect = 5e-10
Identities = 31/73 (42%), Positives = 40/73 (54%), Gaps = 6/73 (8%)
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 845
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 185 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 846 --SCEDGYEKRGD 856
SC GYE D
Sbjct: 245 DSSCGTGYELTED 257
Score = 58.8 bits (136), Expect = 8e-08
Identities = 46/141 (32%), Positives = 56/141 (39%), Gaps = 20/141 (14%)
Query: 21 YLCCCSVGHAW---GAPCEACPPRGSPAHTALCGEKPGEY---------INPVTNET-KP 67
YLC CSVG G CE S + C G Y ++ V T +
Sbjct: 422 YLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCED 481
Query: 68 IDECDIMP--QLCKPGTCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
IDEC + +C C + P FQC C GY C+D+DEC G C
Sbjct: 482 IDECALPTGGHICS-YRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 540
Query: 125 QCVNLPGAFEC---RCPPGYR 142
C N+ GAF C CP YR
Sbjct: 541 TCFNIQGAFRCLAFECPENYR 561
>Z99756-1|CAI18854.1| 988|Homo sapiens protein ( Human DNA sequence
from clone RP1-100N22 on chromosome 22q13.31-13.33. ).
Length = 988
Score = 216 bits (527), Expect = 3e-55
Identities = 145/430 (33%), Positives = 192/430 (44%), Gaps = 50/430 (11%)
Query: 231 VDVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDG 289
VDV+EC EG C + C+NT S++C C PGY +G+ C D+DEC+ + G
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDECENDYYNGGCVH 89
Query: 290 NPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
C N G Y C+C G+ L G C+D DEC++ C C N G Y C+C +G
Sbjct: 90 E--CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSG 146
Query: 348 WRFDKTAAVCVDERKE--LCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
+ C+ E C ++ + G H C E G C+ P
Sbjct: 147 FFLSDNQHTCIHRSNEGMNCMNK-DHGCAH------------ICRETPKGGVACDCRPGF 193
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
D A+ + C LT C C C +TD C C Y L DG +
Sbjct: 194 DLAQNQKDC-------TLT-----CNYGNGGCQHS-CEDTDTGPTCGCHQKYALHSDGRT 240
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRC 524
C++ CA++ C TC +T G C C GFT PD +TC D++EC C C
Sbjct: 241 CIET--CAVNNGGCDR-TCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFC 297
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
NT GSF C C GY + D C+DIDEC E R C H C N GS+ C C GY
Sbjct: 298 RNTVGSFECGCRKGYKLLTDERTCQDIDECSFE-RTCDHICINSPGSFQCLCHRGYILYG 356
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCY 644
C D++EC C G C+NT GS+ C C G +G DC++ TG C
Sbjct: 357 TTH-----CGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCVE--TGKCL 408
Query: 645 -RSLVSGRCE 653
R+ S R +
Sbjct: 409 SRAKTSPRAQ 418
Score = 192 bits (469), Expect = 3e-48
Identities = 143/436 (32%), Positives = 188/436 (43%), Gaps = 55/436 (12%)
Query: 191 DVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE----GGMVCRN 245
DVDECS C + C+N P +Y C C G+K G C D++EC GG V
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK-GEGKQCEDIDECENDYYNGGCV--- 88
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C N G++RC C G+ L DG NC DVDEC + C + C N G YEC C
Sbjct: 89 HECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ----ICVNAMGSYECQCH 144
Query: 306 AGWKLVGRR--CVDRDE----CKELPYVCAGGECRNF-NGGYVCECPAGWRFDKTAAVCV 358
+G+ L + C+ R C + CA CR GG C+C G+ + C
Sbjct: 145 SGFFLSDNQHTCIHRSNEGMNCMNKDHGCAH-ICRETPKGGVACDCRPGFDLAQNQKDCT 203
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAW---GRYC-ERCPA---------P 405
L + G H P C C + A GR C E C
Sbjct: 204 -----LTCNYGNGGCQHSCEDTDTG-PTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCK 257
Query: 406 DSAEFMRI-CQGGMG-RPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAP 461
D+A +R C G +P+ +D++EC V C C NT GSF C C GY L
Sbjct: 258 DTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGC-DHFCRNTVGSFECGCRKGYKLLT 316
Query: 462 DGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCT 521
D +C D DEC+ + R C + C N+ G ++C C G+ C DVDEC+ SC
Sbjct: 317 DERTCQDIDECSFE-RTCDH-ICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCD 374
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA---CENVVGSYIC--KC 576
C NT GS+ C CP G + +G C + +C+ + P A C G C C
Sbjct: 375 QGCVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCFLSC 434
Query: 577 PEGYRRTSAPQDSENA 592
P T DSEN+
Sbjct: 435 P---AHTLFVPDSENS 447
Score = 166 bits (404), Expect = 3e-40
Identities = 139/448 (31%), Positives = 185/448 (41%), Gaps = 65/448 (14%)
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRI---CDHG 165
DVDECS G C A C N P +++C C PGY+ +CED+DEC + C H
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDECENDYYNGGCVH- 89
Query: 166 DCRNTIGSYRCECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK 223
+C N G+YRC C G+ L + C DVDEC C+ C N G+Y C C GF
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSGFF 148
Query: 224 AGPNNDCVDVNECREGGMVCRNGR------CRNT-VGSFRCECAPGYTLTADGRNCRDVD 276
N ++ E GM C N CR T G C+C PG+ L + ++C
Sbjct: 149 LSDNQHTC-IHRSNE-GMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDC--TL 204
Query: 277 ECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGECR 334
C+ C SC +T+ G C C + L GR C+ + C C C+
Sbjct: 205 TCNYGNGGC----QHSCEDTDTGPTCGCHQKYALHSDGRTCI--ETCAVNNGGC-DRTCK 257
Query: 335 NFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAA 394
+ G C CP G+ C D + L + G C + EC C +G
Sbjct: 258 DTATGVRCSCPVGFTLQPDGKTCKDINECLVNN----GGCDHFCRNTVGSFECGCRKGYK 313
Query: 395 WGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECP 454
D R CQ D+DEC C C+N+ GSF+C C
Sbjct: 314 L--------LTDE----RTCQ----------DIDECSFE-RTC-DHICINSPGSFQCLCH 349
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPG-FTQGPDQTCVDVDEC 513
GY+L C D DEC++ C G C NT+G YEC C PG + CV+ +C
Sbjct: 350 RGYILY-GTTHCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCVETGKC 407
Query: 514 ---AEGRASCTFRCHNTAGSFRC--TCP 536
A+ C G C +CP
Sbjct: 408 LSRAKTSPRAQLSCSKAGGVESCFLSCP 435
Score = 158 bits (383), Expect = 9e-38
Identities = 128/440 (29%), Positives = 174/440 (39%), Gaps = 57/440 (12%)
Query: 68 IDECDIMPQLCK-PGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
+DEC C C +TP ++C C GY+ + C D+DEC + +C
Sbjct: 34 VDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQ--CEDIDECENDYYNGGCVHEC 91
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
+N+PG + C C G+ L C DVDEC D C N +GSY C+C G+ L +
Sbjct: 92 INIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSD 151
Query: 187 N--VC----RDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREG 239
N C + C C + E G C C GF N DC C G
Sbjct: 152 NQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDC--TLTCNYG 209
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGG 299
C++ C +T C C Y L +DGR C ++ C C R +C +T G
Sbjct: 210 NGGCQHS-CEDTDTGPTCGCHQKYALHSDGRTC--IETCAVNNGGCDR----TCKDTATG 262
Query: 300 YECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVC 357
CSC G+ L G+ C D +EC C CRN G + C C G++ +
Sbjct: 263 VRCSCPVGFTLQPDGKTCKDINECLVNNGGC-DHFCRNTVGSFECGCRKGYK------LL 315
Query: 358 VDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG 417
DER C D EC ++ R C+ F +C G
Sbjct: 316 TDER--TCQD----------------IDEC------SFERTCDHICINSPGSFQCLCHRG 351
Query: 418 MGRPNLTQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
T D+DEC + C G CVNT GS+ C CP G L +G CV+ +C
Sbjct: 352 YILYGTTHCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSR 410
Query: 476 PRICGNG--TCSNTRGGYEC 493
+ +CS G C
Sbjct: 411 AKTSPRAQLSCSKAGGVESC 430
Score = 106 bits (254), Expect = 4e-22
Identities = 50/115 (43%), Positives = 63/115 (54%), Gaps = 10/115 (8%)
Query: 747 DVDECAA------IPGLC--APGRFRCVCGPGYRPAGEVCADVDECA--VRPPPCDQLCH 796
DVDEC+ I +C P ++C+C PGY+ G+ C D+DEC C C
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHECI 92
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
N G+Y C C G+ L DG NC DVDEC+ + CQQIC N GSYEC C G+
Sbjct: 93 NIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGF 147
Score = 99.1 bits (236), Expect = 6e-20
Identities = 41/90 (45%), Positives = 55/90 (61%), Gaps = 3/90 (3%)
Query: 764 RCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 821
RC C G+ +P G+ C D++EC V CD C NT GS++C CR GY+L D C+D
Sbjct: 264 RCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQD 323
Query: 822 VDECERDTHTCQQICSNTEGSYECSCEDGY 851
+DEC + TC IC N+ GS++C C GY
Sbjct: 324 IDECSFE-RTCDHICINSPGSFQCLCHRGY 352
Score = 91.9 bits (218), Expect = 9e-18
Identities = 46/112 (41%), Positives = 58/112 (51%), Gaps = 10/112 (8%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNT 798
D++EC G C G F C C GY+ + C D+DEC+ CD +C N+
Sbjct: 282 DINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERT-CDHICINS 340
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
GS+ CLC GY L +C DVDEC +C Q C NT+GSYEC C G
Sbjct: 341 PGSFQCLCHRGYIL-YGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPG 391
Score = 76.2 bits (179), Expect = 5e-13
Identities = 40/108 (37%), Positives = 56/108 (51%), Gaps = 9/108 (8%)
Query: 747 DVDECA---AIPGLC--APGRFRCVCGPGYRPAGEV-CADVDECAVRPPPCDQLCHNTDG 800
D+DEC+ +C +PG F+C+C GY G C DVDEC++ CDQ C NT G
Sbjct: 323 DIDECSFERTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKG 382
Query: 801 SYDCLCRTGYELDEDGANCRDVDEC---ERDTHTCQQICSNTEGSYEC 845
SY+C+C G L +G +C + +C + + Q CS G C
Sbjct: 383 SYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESC 430
Score = 75.8 bits (178), Expect = 6e-13
Identities = 36/100 (36%), Positives = 48/100 (48%), Gaps = 7/100 (7%)
Query: 760 PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG +RC C G+ A G C DVDEC C Q+C N GSY+C C +G+ L ++
Sbjct: 95 PGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQH 154
Query: 818 NC----RDVDECERDTHTCQQICSNT-EGSYECSCEDGYE 852
C + C H C IC T +G C C G++
Sbjct: 155 TCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFD 194
Score = 75.8 bits (178), Expect = 6e-13
Identities = 31/88 (35%), Positives = 43/88 (48%)
Query: 765 CVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDE 824
C C Y + ++ CAV CD+ C +T C C G+ L DG C+D++E
Sbjct: 226 CGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINE 285
Query: 825 CERDTHTCQQICSNTEGSYECSCEDGYE 852
C + C C NT GS+EC C GY+
Sbjct: 286 CLVNNGGCDHFCRNTVGSFECGCRKGYK 313
Score = 52.0 bits (119), Expect = 9e-06
Identities = 30/106 (28%), Positives = 39/106 (36%), Gaps = 2/106 (1%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
CA I G C C PG+ A C C C +TD C C Y
Sbjct: 173 CAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKY 232
Query: 811 ELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
L DG C ++ C + C + C +T CSC G+ + D
Sbjct: 233 ALHSDGRTC--IETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPD 276
Score = 44.8 bits (101), Expect = 0.001
Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Query: 821 DVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDAC 858
DVDEC T C IC NT SY+C C+ GY+ G C
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQC 72
>Z82214-3|CAI21674.1| 988|Homo sapiens protein ( Human DNA sequence
from clone RP3-526I14 on chromosome 22. ).
Length = 988
Score = 216 bits (527), Expect = 3e-55
Identities = 145/430 (33%), Positives = 192/430 (44%), Gaps = 50/430 (11%)
Query: 231 VDVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDG 289
VDV+EC EG C + C+NT S++C C PGY +G+ C D+DEC+ + G
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDECENDYYNGGCVH 89
Query: 290 NPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
C N G Y C+C G+ L G C+D DEC++ C C N G Y C+C +G
Sbjct: 90 E--CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSG 146
Query: 348 WRFDKTAAVCVDERKE--LCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
+ C+ E C ++ + G H C E G C+ P
Sbjct: 147 FFLSDNQHTCIHRSNEGMNCMNK-DHGCAH------------ICRETPKGGVACDCRPGF 193
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
D A+ + C LT C C C +TD C C Y L DG +
Sbjct: 194 DLAQNQKDC-------TLT-----CNYGNGGCQHS-CEDTDTGPTCGCHQKYALHSDGRT 240
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRC 524
C++ CA++ C TC +T G C C GFT PD +TC D++EC C C
Sbjct: 241 CIET--CAVNNGGCDR-TCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFC 297
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
NT GSF C C GY + D C+DIDEC E R C H C N GS+ C C GY
Sbjct: 298 RNTVGSFECGCRKGYKLLTDERTCQDIDECSFE-RTCDHICINSPGSFQCLCHRGYILYG 356
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCY 644
C D++EC C G C+NT GS+ C C G +G DC++ TG C
Sbjct: 357 TTH-----CGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCVE--TGKCL 408
Query: 645 -RSLVSGRCE 653
R+ S R +
Sbjct: 409 SRAKTSPRAQ 418
Score = 192 bits (469), Expect = 3e-48
Identities = 143/436 (32%), Positives = 188/436 (43%), Gaps = 55/436 (12%)
Query: 191 DVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE----GGMVCRN 245
DVDECS C + C+N P +Y C C G+K G C D++EC GG V
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK-GEGKQCEDIDECENDYYNGGCV--- 88
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C N G++RC C G+ L DG NC DVDEC + C + C N G YEC C
Sbjct: 89 HECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ----ICVNAMGSYECQCH 144
Query: 306 AGWKLVGRR--CVDRDE----CKELPYVCAGGECRNF-NGGYVCECPAGWRFDKTAAVCV 358
+G+ L + C+ R C + CA CR GG C+C G+ + C
Sbjct: 145 SGFFLSDNQHTCIHRSNEGMNCMNKDHGCAH-ICRETPKGGVACDCRPGFDLAQNQKDCT 203
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAW---GRYC-ERCPA---------P 405
L + G H P C C + A GR C E C
Sbjct: 204 -----LTCNYGNGGCQHSCEDTDTG-PTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCK 257
Query: 406 DSAEFMRI-CQGGMG-RPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAP 461
D+A +R C G +P+ +D++EC V C C NT GSF C C GY L
Sbjct: 258 DTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGC-DHFCRNTVGSFECGCRKGYKLLT 316
Query: 462 DGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCT 521
D +C D DEC+ + R C + C N+ G ++C C G+ C DVDEC+ SC
Sbjct: 317 DERTCQDIDECSFE-RTCDH-ICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCD 374
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA---CENVVGSYIC--KC 576
C NT GS+ C CP G + +G C + +C+ + P A C G C C
Sbjct: 375 QGCVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCFLSC 434
Query: 577 PEGYRRTSAPQDSENA 592
P T DSEN+
Sbjct: 435 P---AHTLFVPDSENS 447
Score = 166 bits (404), Expect = 3e-40
Identities = 139/448 (31%), Positives = 185/448 (41%), Gaps = 65/448 (14%)
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRI---CDHG 165
DVDECS G C A C N P +++C C PGY+ +CED+DEC + C H
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDECENDYYNGGCVH- 89
Query: 166 DCRNTIGSYRCECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK 223
+C N G+YRC C G+ L + C DVDEC C+ C N G+Y C C GF
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSGFF 148
Query: 224 AGPNNDCVDVNECREGGMVCRNGR------CRNT-VGSFRCECAPGYTLTADGRNCRDVD 276
N ++ E GM C N CR T G C+C PG+ L + ++C
Sbjct: 149 LSDNQHTC-IHRSNE-GMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDC--TL 204
Query: 277 ECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGECR 334
C+ C SC +T+ G C C + L GR C+ + C C C+
Sbjct: 205 TCNYGNGGC----QHSCEDTDTGPTCGCHQKYALHSDGRTCI--ETCAVNNGGC-DRTCK 257
Query: 335 NFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAA 394
+ G C CP G+ C D + L + G C + EC C +G
Sbjct: 258 DTATGVRCSCPVGFTLQPDGKTCKDINECLVNN----GGCDHFCRNTVGSFECGCRKGYK 313
Query: 395 WGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECP 454
D R CQ D+DEC C C+N+ GSF+C C
Sbjct: 314 L--------LTDE----RTCQ----------DIDECSFE-RTC-DHICINSPGSFQCLCH 349
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPG-FTQGPDQTCVDVDEC 513
GY+L C D DEC++ C G C NT+G YEC C PG + CV+ +C
Sbjct: 350 RGYILY-GTTHCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCVETGKC 407
Query: 514 ---AEGRASCTFRCHNTAGSFRC--TCP 536
A+ C G C +CP
Sbjct: 408 LSRAKTSPRAQLSCSKAGGVESCFLSCP 435
Score = 158 bits (383), Expect = 9e-38
Identities = 128/440 (29%), Positives = 174/440 (39%), Gaps = 57/440 (12%)
Query: 68 IDECDIMPQLCK-PGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
+DEC C C +TP ++C C GY+ + C D+DEC + +C
Sbjct: 34 VDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQ--CEDIDECENDYYNGGCVHEC 91
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
+N+PG + C C G+ L C DVDEC D C N +GSY C+C G+ L +
Sbjct: 92 INIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSD 151
Query: 187 N--VC----RDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREG 239
N C + C C + E G C C GF N DC C G
Sbjct: 152 NQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDC--TLTCNYG 209
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGG 299
C++ C +T C C Y L +DGR C ++ C C R +C +T G
Sbjct: 210 NGGCQHS-CEDTDTGPTCGCHQKYALHSDGRTC--IETCAVNNGGCDR----TCKDTATG 262
Query: 300 YECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVC 357
CSC G+ L G+ C D +EC C CRN G + C C G++ +
Sbjct: 263 VRCSCPVGFTLQPDGKTCKDINECLVNNGGC-DHFCRNTVGSFECGCRKGYK------LL 315
Query: 358 VDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG 417
DER C D EC ++ R C+ F +C G
Sbjct: 316 TDER--TCQD----------------IDEC------SFERTCDHICINSPGSFQCLCHRG 351
Query: 418 MGRPNLTQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
T D+DEC + C G CVNT GS+ C CP G L +G CV+ +C
Sbjct: 352 YILYGTTHCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSR 410
Query: 476 PRICGNG--TCSNTRGGYEC 493
+ +CS G C
Sbjct: 411 AKTSPRAQLSCSKAGGVESC 430
Score = 106 bits (254), Expect = 4e-22
Identities = 50/115 (43%), Positives = 63/115 (54%), Gaps = 10/115 (8%)
Query: 747 DVDECAA------IPGLC--APGRFRCVCGPGYRPAGEVCADVDECA--VRPPPCDQLCH 796
DVDEC+ I +C P ++C+C PGY+ G+ C D+DEC C C
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHECI 92
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
N G+Y C C G+ L DG NC DVDEC+ + CQQIC N GSYEC C G+
Sbjct: 93 NIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGF 147
Score = 99.1 bits (236), Expect = 6e-20
Identities = 41/90 (45%), Positives = 55/90 (61%), Gaps = 3/90 (3%)
Query: 764 RCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 821
RC C G+ +P G+ C D++EC V CD C NT GS++C CR GY+L D C+D
Sbjct: 264 RCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQD 323
Query: 822 VDECERDTHTCQQICSNTEGSYECSCEDGY 851
+DEC + TC IC N+ GS++C C GY
Sbjct: 324 IDECSFE-RTCDHICINSPGSFQCLCHRGY 352
Score = 91.9 bits (218), Expect = 9e-18
Identities = 46/112 (41%), Positives = 58/112 (51%), Gaps = 10/112 (8%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNT 798
D++EC G C G F C C GY+ + C D+DEC+ CD +C N+
Sbjct: 282 DINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERT-CDHICINS 340
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
GS+ CLC GY L +C DVDEC +C Q C NT+GSYEC C G
Sbjct: 341 PGSFQCLCHRGYIL-YGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPG 391
Score = 76.2 bits (179), Expect = 5e-13
Identities = 40/108 (37%), Positives = 56/108 (51%), Gaps = 9/108 (8%)
Query: 747 DVDECA---AIPGLC--APGRFRCVCGPGYRPAGEV-CADVDECAVRPPPCDQLCHNTDG 800
D+DEC+ +C +PG F+C+C GY G C DVDEC++ CDQ C NT G
Sbjct: 323 DIDECSFERTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKG 382
Query: 801 SYDCLCRTGYELDEDGANCRDVDEC---ERDTHTCQQICSNTEGSYEC 845
SY+C+C G L +G +C + +C + + Q CS G C
Sbjct: 383 SYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESC 430
Score = 75.8 bits (178), Expect = 6e-13
Identities = 36/100 (36%), Positives = 48/100 (48%), Gaps = 7/100 (7%)
Query: 760 PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG +RC C G+ A G C DVDEC C Q+C N GSY+C C +G+ L ++
Sbjct: 95 PGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQH 154
Query: 818 NC----RDVDECERDTHTCQQICSNT-EGSYECSCEDGYE 852
C + C H C IC T +G C C G++
Sbjct: 155 TCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFD 194
Score = 75.8 bits (178), Expect = 6e-13
Identities = 31/88 (35%), Positives = 43/88 (48%)
Query: 765 CVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDE 824
C C Y + ++ CAV CD+ C +T C C G+ L DG C+D++E
Sbjct: 226 CGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINE 285
Query: 825 CERDTHTCQQICSNTEGSYECSCEDGYE 852
C + C C NT GS+EC C GY+
Sbjct: 286 CLVNNGGCDHFCRNTVGSFECGCRKGYK 313
Score = 52.0 bits (119), Expect = 9e-06
Identities = 30/106 (28%), Positives = 39/106 (36%), Gaps = 2/106 (1%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
CA I G C C PG+ A C C C +TD C C Y
Sbjct: 173 CAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKY 232
Query: 811 ELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
L DG C ++ C + C + C +T CSC G+ + D
Sbjct: 233 ALHSDGRTC--IETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPD 276
Score = 44.8 bits (101), Expect = 0.001
Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Query: 821 DVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDAC 858
DVDEC T C IC NT SY+C C+ GY+ G C
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQC 72
>U01244-1|AAB17099.1| 703|Homo sapiens fibulin-1D protein.
Length = 703
Score = 216 bits (527), Expect = 3e-55
Identities = 152/444 (34%), Positives = 209/444 (47%), Gaps = 63/444 (14%)
Query: 193 DECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGR-CRN 250
D C P C+ C + +C C G++ + C DVNEC G CR G C N
Sbjct: 178 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 251 TVGSFRCE----CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC---- 302
TVGSFRC+ C GY LT D +C+D+DEC+ H C D C NT G + C
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDF--ICQNTLGSFRCRPKL 292
Query: 303 SCGAGW--KLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCE-----CPAGWRFDKTA 354
C +G+ +G C+D +EC + C G C N G Y C+ C G+ ++
Sbjct: 293 QCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEG 351
Query: 355 AVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC 414
CVD E G+ HR C S G+ RC F
Sbjct: 352 TRCVDV-DECAPPAEPCGKGHR----------CVNSPGSF------RCECKTGYYF---- 390
Query: 415 QGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECAL 474
G+ R + D++EC+ P G +C NT GS+ C C G+ L+ DG SC D +EC+
Sbjct: 391 -DGISR--MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 475 DPRICGNGTCSNTRGGYECQCSPGF--TQGPDQTCVDVDECA--EGRASCTFRCHNTAGS 530
P C C+N G Y+C C G+ + TC D+DECA G C++RC N GS
Sbjct: 448 SP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 504
Query: 531 FRCTCP-YGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC---KCPEGYRRTS 584
F+C+CP GY +A +G +C+DIDECV C C N+ G++ C +CPE YRR++
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENYRRSA 564
Query: 585 A--PQDSENACEDINECEEQEDLC 606
A Q+ + I C + C
Sbjct: 565 ATLQQEKTDTVRCIKSCRPNDVTC 588
Score = 208 bits (508), Expect = 6e-53
Identities = 147/407 (36%), Positives = 200/407 (49%), Gaps = 53/407 (13%)
Query: 234 NECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+ CR GG C+ +CR+T C C GY L +DG +C DV+EC H C R G SC
Sbjct: 178 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC-RLGE-SC 233
Query: 294 TNTNGGYEC----SCGAGWKLV-GRRCVDRDECKELPYVCAGGE-CRNFNGGYVC----E 343
NT G + C SCG G++L C D DEC+ + C C+N G + C +
Sbjct: 234 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
C +G+ D C+D + L + P + C +EG+ C++
Sbjct: 294 CKSGFIQDALGN-CIDINECLSI----------SAPCPIGHT-CINTEGSYT---CQK-N 337
Query: 404 APDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPD 462
P+ + + G D+DEC + C G RCVN+ GSFRCEC GY D
Sbjct: 338 VPNCGRGYHLNEEG----TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF--D 391
Query: 463 GLS--CVDADECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRA 518
G+S CVD +EC P R+CG+ C NT G Y C CS GF D ++C D++EC+ +
Sbjct: 392 GISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS--S 448
Query: 519 SCTFRCHNTAGSFRCTCPYGYAVA-ADGVHCRDIDECVQEP--RVCPHACENVVGSYICK 575
C+ C N GS++C C GY ++ DGV C DIDEC +C + C N+ GS+ C
Sbjct: 449 PCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCS 508
Query: 576 CP-EGYRRTSAPQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
CP GYR AP C+DI+EC CS C N G+F C
Sbjct: 509 CPSSGYR--LAPNGRN--CQDIDECVTGIHNCSINETCFNIQGAFRC 551
Score = 206 bits (503), Expect = 3e-52
Identities = 137/407 (33%), Positives = 184/407 (45%), Gaps = 57/407 (14%)
Query: 111 DECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GDQRICDHGD-CR 168
D C G P C+ QC + C C GY+L CEDV+EC C G+ C
Sbjct: 178 DRCRGGGP-CK--QQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCI 234
Query: 169 NTIGSYRCE----CKPGYTLRE-NVCRDVDECSRPRPVCR-NGTCENLPGAYLCH----C 218
NT+GS+RC+ C GY L E N C+D+DEC C + C+N G++ C C
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294
Query: 219 DDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCE-----CAPGYTLTADGRNC 272
GF +C+D+NEC C G C NT GS+ C+ C GY L +G C
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354
Query: 273 RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAG 330
DVDEC PCG+ C N+ G + C C G+ G R CVD +EC+ P G
Sbjct: 355 VDVDECAPPAEPCGKGHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCS 390
+C N G Y+C C G+R C D +E + C + C +
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDGRSCED------INECSSSPCSQE----------CAN 456
Query: 391 EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP--DVCVGGRCVNTDGS 448
++ YC R + + C +D+DEC + +C RC+N GS
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGV-TC----------EDIDECALPTGGHIC-SYRCINIPGS 504
Query: 449 FRCECP-DGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
F+C CP GY LAP+G +C D DEC C N TC N +G + C
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRC 551
Score = 193 bits (470), Expect = 3e-48
Identities = 138/405 (34%), Positives = 176/405 (43%), Gaps = 55/405 (13%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECR- 136
CK C DT C C GY+ + C DV+EC G CR C+N G+F C+
Sbjct: 186 CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 137 ---CPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIGSYRC----ECKPGYTLRE- 186
C GY LT + C+D+DEC G C+NT+GS+RC +CK G+
Sbjct: 245 DSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 187 NVCRDVDECSRPRPVCRNG-TCENLPGAYLC-----HCDDGFKAGPNND-CVDVNECREG 239
C D++EC C G TC N G+Y C +C G+ CVDV+EC
Sbjct: 304 GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPP 363
Query: 240 GMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
C G RC N+ GSFRCEC GY R C DV+EC P GR C NT G
Sbjct: 364 AEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYP---GRLCGHKCENTLG 420
Query: 299 GYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
Y CSC G++L GR C D +EC P C+ EC N G Y C C G++ V
Sbjct: 421 SYLCSCSVGFRLSVDGRSCEDINECSSSP--CS-QECANVYGSYQCYCRRGYQLSDVDGV 477
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
++ E C + C G+ +C P S R+
Sbjct: 478 TCEDIDE----------CALPTGGHICSYRCINIPGSF------QCSCPSSG--YRLAPN 519
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRC---ECPDGY 457
G QD+DEC C + C N G+FRC ECP+ Y
Sbjct: 520 GRN----CQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENY 560
Score = 175 bits (427), Expect = 4e-43
Identities = 127/374 (33%), Positives = 174/374 (46%), Gaps = 52/374 (13%)
Query: 287 RDGNP---SCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGE-CRNFNGGY 340
R G P C +T CSC G++L+ G C D +EC + C GE C N G +
Sbjct: 181 RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 240
Query: 341 VCE----CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWG 396
C+ C G+ + + C D DE E+G + P+ C G
Sbjct: 241 RCQRDSSCGTGYELTEDNS-CKD------IDECESG-------IHNCLPDFICQN--TLG 284
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCE--- 452
+ RC P Q +G D++EC C +G C+NT+GS+ C+
Sbjct: 285 SF--RC-RPKLQCKSGFIQDALGN---CIDINECLSISAPCPIGHTCINTEGSYTCQKNV 338
Query: 453 --CPDGYVLAPDGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFT-QGPDQTCV 508
C GY L +G CVD DECA CG G C N+ G + C+C G+ G + CV
Sbjct: 339 PNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV 398
Query: 509 DVDECAE--GRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
DV+EC GR C +C NT GS+ C+C G+ ++ DG C DI+EC P C C
Sbjct: 399 DVNECQRYPGRL-CGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQECA 455
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED--LCSGGVCINTDGSFLCDC-D 623
NV GSY C C GY+ + + CEDI+EC +CS CIN GSF C C
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVT---CEDIDECALPTGGHICSYR-CINIPGSFQCSCPS 511
Query: 624 AGFEPSEDGTDCID 637
+G+ + +G +C D
Sbjct: 512 SGYRLAPNGRNCQD 525
Score = 165 bits (400), Expect = 8e-40
Identities = 94/250 (37%), Positives = 127/250 (50%), Gaps = 22/250 (8%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQC-----GCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
I+EC + C G TC +T + C C GY + C DVDEC+ PC
Sbjct: 309 INECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCG 368
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG--DQRICDHGDCRNTIGSYRCECK 179
+CVN PG+F C C GY C DV+EC R+C H C NT+GSY C C
Sbjct: 369 KGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCS 427
Query: 180 PGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN--DCVDVNE 235
G+ L + C D++ECS P + C N+ G+Y C+C G++ + C D++E
Sbjct: 428 VGFRLSVDGRSCEDINECS-SSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDE 484
Query: 236 CR--EGGMVCRNGRCRNTVGSFRCEC-APGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
C GG +C + RC N GSF+C C + GY L +GRNC+D+DEC H C N +
Sbjct: 485 CALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI--NET 541
Query: 293 CTNTNGGYEC 302
C N G + C
Sbjct: 542 CFNIQGAFRC 551
Score = 151 bits (365), Expect = 1e-35
Identities = 91/247 (36%), Positives = 112/247 (45%), Gaps = 26/247 (10%)
Query: 425 QDLDECRVRPDVC-VGGRCVNTDGSFRCE----CPDGYVLAPDGLSCVDADECALDPRIC 479
+D++EC C +G C+NT GSFRC+ C GY L D SC D DEC C
Sbjct: 215 EDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNC 273
Query: 480 -GNGTCSNTRGGYEC----QCSPGFTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFR 532
+ C NT G + C QC GF Q C+D++EC A C C NT GS+
Sbjct: 274 LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 533 C-----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSA 585
C C GY + +G C D+DEC C H C N GS+ C+C GY
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 586 PQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYR 645
+ C D+NEC+ G C NT GS+LC C GF S DG C D C
Sbjct: 394 SR----MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED--INECSS 447
Query: 646 SLVSGRC 652
S S C
Sbjct: 448 SPCSQEC 454
Score = 136 bits (328), Expect = 4e-31
Identities = 90/266 (33%), Positives = 122/266 (45%), Gaps = 33/266 (12%)
Query: 416 GGMGRPNLTQDLDECRVRP---DVCVGG-----RCVNTDGSFRCECPDGYVLAPDGLSCV 467
GG+ + +++E + P D C GG +C +T C C GY L DG+SC
Sbjct: 156 GGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCE 215
Query: 468 DADECALDPRICGNG-TCSNTRGGYECQ----CSPGFTQGPDQTCVDVDECAEGRASC-- 520
D +EC C G +C NT G + CQ C G+ D +C D+DEC G +C
Sbjct: 216 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLP 275
Query: 521 TFRCHNTAGSFRC----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC 574
F C NT GSFRC C G+ A G +C DI+EC+ CP H C N GSY C
Sbjct: 276 DFICQNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTC 334
Query: 575 K-----CPEGYRRTSAPQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFEP 628
+ C GY + C D++EC + C G C+N+ GSF C+C G+
Sbjct: 335 QKNVPNCGRGYHL----NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 629 SEDGTDCIDRRTGTCYRSLVSG-RCE 653
C+D Y + G +CE
Sbjct: 391 DGISRMCVDVNECQRYPGRLCGHKCE 416
Score = 99.1 bits (236), Expect = 6e-20
Identities = 59/176 (33%), Positives = 85/176 (48%), Gaps = 15/176 (8%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C K G Y + ++ ++EC P C +T + C C G+ C D
Sbjct: 382 CECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED 441
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD--ECEDVDECG---DQRICDH 164
++ECS PC +C N+ G+++C C GY+L+ +D CED+DEC IC +
Sbjct: 442 INECS--SSPC--SQECANVYGSYQCYCRRGYQLS-DVDGVTCEDIDECALPTGGHICSY 496
Query: 165 GDCRNTIGSYRCEC-KPGYTLREN--VCRDVDECSRPRPVCR-NGTCENLPGAYLC 216
C N GS++C C GY L N C+D+DEC C N TC N+ GA+ C
Sbjct: 497 -RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRC 551
Score = 97.9 bits (233), Expect = 1e-19
Identities = 52/118 (44%), Positives = 63/118 (53%), Gaps = 15/118 (12%)
Query: 747 DVDECAAIPG-LCAP------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
DV+EC PG LC G + C C G+R + G C D++EC+ PC Q C N
Sbjct: 399 DVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECAN 456
Query: 798 TDGSYDCLCRTGYEL-DEDGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGY 851
GSY C CR GY+L D DG C D+DEC T H C C N GS++CSC GY
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGY 514
Score = 96.3 bits (229), Expect = 4e-19
Identities = 50/117 (42%), Positives = 61/117 (52%), Gaps = 13/117 (11%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAG--EVCADVDECAVRPPP-CDQLC 795
DVDECA C +PG FRC C GY G +C DV+EC P C C
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 415
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
NT GSY C C G+ L DG +C D++EC + C Q C+N GSY+C C GY+
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQ 470
Score = 81.4 bits (192), Expect = 1e-14
Identities = 43/122 (35%), Positives = 64/122 (52%), Gaps = 15/122 (12%)
Query: 747 DVDECAAIPGL--CAP--GRFRCVCGPGYRPA---GEVCADVDECAVRPPP--CDQLCHN 797
D++EC++ P CA G ++C C GY+ + G C D+DECA+ C C N
Sbjct: 441 DINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 798 TDGSYDCLC-RTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC---SCEDGY 851
GS+ C C +GY L +G NC+D+DEC H C + C N +G++ C C + Y
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENY 560
Query: 852 EK 853
+
Sbjct: 561 RR 562
Score = 75.4 bits (177), Expect = 8e-13
Identities = 47/127 (37%), Positives = 60/127 (47%), Gaps = 22/127 (17%)
Query: 747 DVDECAAIPGLCAP--------GRFRC----VCGPGY-RPAGEVCADVDECAVRPPPCD- 792
D+DEC + C P G FRC C G+ + A C D++EC PC
Sbjct: 262 DIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPI 321
Query: 793 -QLCHNTDGSYDCL-----CRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 844
C NT+GSY C C GY L+E+G C DVDEC C + C N+ GS+
Sbjct: 322 GHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 845 CSCEDGY 851
C C+ GY
Sbjct: 382 CECKTGY 388
Score = 72.1 bits (169), Expect = 8e-12
Identities = 42/101 (41%), Positives = 52/101 (51%), Gaps = 15/101 (14%)
Query: 765 CVCGPGYR--PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCL----CRTGYELDEDG 816
C C GY+ G C DV+EC C + C NT GS+ C C TGYEL ED
Sbjct: 199 CSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN 258
Query: 817 ANCRDVDECERDTHTC--QQICSNTEGSYEC----SCEDGY 851
+ C+D+DECE H C IC NT GS+ C C+ G+
Sbjct: 259 S-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 298
Score = 66.1 bits (154), Expect = 5e-10
Identities = 31/73 (42%), Positives = 40/73 (54%), Gaps = 6/73 (8%)
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 845
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 185 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 846 --SCEDGYEKRGD 856
SC GYE D
Sbjct: 245 DSSCGTGYELTED 257
Score = 60.5 bits (140), Expect = 2e-08
Identities = 50/165 (30%), Positives = 64/165 (38%), Gaps = 20/165 (12%)
Query: 21 YLCCCSVGHAW---GAPCEACPPRGSPAHTALCGEKPGEY---------INPVTNET-KP 67
YLC CSVG G CE S + C G Y ++ V T +
Sbjct: 422 YLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCED 481
Query: 68 IDECDIMP--QLCKPGTCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
IDEC + +C C + P FQC C GY C+D+DEC G C
Sbjct: 482 IDECALPTGGHICS-YRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 540
Query: 125 QCVNLPGAFEC---RCPPGYRLTPSLDECEDVDECGDQRICDHGD 166
C N+ GAF C CP YR + + + E D + C D
Sbjct: 541 TCFNIQGAFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPND 585
>AF126110-1|AAK37822.1| 703|Homo sapiens fibulin-1 isoform D
precursor protein.
Length = 703
Score = 216 bits (527), Expect = 3e-55
Identities = 152/444 (34%), Positives = 209/444 (47%), Gaps = 63/444 (14%)
Query: 193 DECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGR-CRN 250
D C P C+ C + +C C G++ + C DVNEC G CR G C N
Sbjct: 178 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 251 TVGSFRCE----CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC---- 302
TVGSFRC+ C GY LT D +C+D+DEC+ H C D C NT G + C
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDF--ICQNTLGSFRCRPKL 292
Query: 303 SCGAGW--KLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCE-----CPAGWRFDKTA 354
C +G+ +G C+D +EC + C G C N G Y C+ C G+ ++
Sbjct: 293 QCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEG 351
Query: 355 AVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC 414
CVD E G+ HR C S G+ RC F
Sbjct: 352 TRCVDV-DECAPPAEPCGKGHR----------CVNSPGSF------RCECKTGYYF---- 390
Query: 415 QGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECAL 474
G+ R + D++EC+ P G +C NT GS+ C C G+ L+ DG SC D +EC+
Sbjct: 391 -DGISR--MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 475 DPRICGNGTCSNTRGGYECQCSPGF--TQGPDQTCVDVDECA--EGRASCTFRCHNTAGS 530
P C C+N G Y+C C G+ + TC D+DECA G C++RC N GS
Sbjct: 448 SP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 504
Query: 531 FRCTCP-YGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC---KCPEGYRRTS 584
F+C+CP GY +A +G +C+DIDECV C C N+ G++ C +CPE YRR++
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENYRRSA 564
Query: 585 A--PQDSENACEDINECEEQEDLC 606
A Q+ + I C + C
Sbjct: 565 ATLQQEKTDTVRCIKSCRPNDVTC 588
Score = 208 bits (508), Expect = 6e-53
Identities = 147/407 (36%), Positives = 200/407 (49%), Gaps = 53/407 (13%)
Query: 234 NECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+ CR GG C+ +CR+T C C GY L +DG +C DV+EC H C R G SC
Sbjct: 178 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC-RLGE-SC 233
Query: 294 TNTNGGYEC----SCGAGWKLV-GRRCVDRDECKELPYVCAGGE-CRNFNGGYVC----E 343
NT G + C SCG G++L C D DEC+ + C C+N G + C +
Sbjct: 234 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
C +G+ D C+D + L + P + C +EG+ C++
Sbjct: 294 CKSGFIQDALGN-CIDINECLSI----------SAPCPIGHT-CINTEGSYT---CQK-N 337
Query: 404 APDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPD 462
P+ + + G D+DEC + C G RCVN+ GSFRCEC GY D
Sbjct: 338 VPNCGRGYHLNEEG----TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF--D 391
Query: 463 GLS--CVDADECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRA 518
G+S CVD +EC P R+CG+ C NT G Y C CS GF D ++C D++EC+ +
Sbjct: 392 GISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS--S 448
Query: 519 SCTFRCHNTAGSFRCTCPYGYAVA-ADGVHCRDIDECVQEP--RVCPHACENVVGSYICK 575
C+ C N GS++C C GY ++ DGV C DIDEC +C + C N+ GS+ C
Sbjct: 449 PCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCS 508
Query: 576 CP-EGYRRTSAPQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
CP GYR AP C+DI+EC CS C N G+F C
Sbjct: 509 CPSSGYR--LAPNGRN--CQDIDECVTGIHNCSINETCFNIQGAFRC 551
Score = 206 bits (503), Expect = 3e-52
Identities = 137/407 (33%), Positives = 184/407 (45%), Gaps = 57/407 (14%)
Query: 111 DECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GDQRICDHGD-CR 168
D C G P C+ QC + C C GY+L CEDV+EC C G+ C
Sbjct: 178 DRCRGGGP-CK--QQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCI 234
Query: 169 NTIGSYRCE----CKPGYTLRE-NVCRDVDECSRPRPVCR-NGTCENLPGAYLCH----C 218
NT+GS+RC+ C GY L E N C+D+DEC C + C+N G++ C C
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294
Query: 219 DDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCE-----CAPGYTLTADGRNC 272
GF +C+D+NEC C G C NT GS+ C+ C GY L +G C
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354
Query: 273 RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAG 330
DVDEC PCG+ C N+ G + C C G+ G R CVD +EC+ P G
Sbjct: 355 VDVDECAPPAEPCGKGHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCS 390
+C N G Y+C C G+R C D +E + C + C +
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDGRSCED------INECSSSPCSQE----------CAN 456
Query: 391 EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP--DVCVGGRCVNTDGS 448
++ YC R + + C +D+DEC + +C RC+N GS
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGV-TC----------EDIDECALPTGGHIC-SYRCINIPGS 504
Query: 449 FRCECP-DGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
F+C CP GY LAP+G +C D DEC C N TC N +G + C
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRC 551
Score = 193 bits (470), Expect = 3e-48
Identities = 138/405 (34%), Positives = 176/405 (43%), Gaps = 55/405 (13%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECR- 136
CK C DT C C GY+ + C DV+EC G CR C+N G+F C+
Sbjct: 186 CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 137 ---CPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIGSYRC----ECKPGYTLRE- 186
C GY LT + C+D+DEC G C+NT+GS+RC +CK G+
Sbjct: 245 DSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 187 NVCRDVDECSRPRPVCRNG-TCENLPGAYLC-----HCDDGFKAGPNND-CVDVNECREG 239
C D++EC C G TC N G+Y C +C G+ CVDV+EC
Sbjct: 304 GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPP 363
Query: 240 GMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
C G RC N+ GSFRCEC GY R C DV+EC P GR C NT G
Sbjct: 364 AEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYP---GRLCGHKCENTLG 420
Query: 299 GYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
Y CSC G++L GR C D +EC P C+ EC N G Y C C G++ V
Sbjct: 421 SYLCSCSVGFRLSVDGRSCEDINECSSSP--CS-QECANVYGSYQCYCRRGYQLSDVDGV 477
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
++ E C + C G+ +C P S R+
Sbjct: 478 TCEDIDE----------CALPTGGHICSYRCINIPGSF------QCSCPSSG--YRLAPN 519
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRC---ECPDGY 457
G QD+DEC C + C N G+FRC ECP+ Y
Sbjct: 520 GRN----CQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENY 560
Score = 175 bits (427), Expect = 4e-43
Identities = 127/374 (33%), Positives = 174/374 (46%), Gaps = 52/374 (13%)
Query: 287 RDGNP---SCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGE-CRNFNGGY 340
R G P C +T CSC G++L+ G C D +EC + C GE C N G +
Sbjct: 181 RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 240
Query: 341 VCE----CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWG 396
C+ C G+ + + C D DE E+G + P+ C G
Sbjct: 241 RCQRDSSCGTGYELTEDNS-CKD------IDECESG-------IHNCLPDFICQN--TLG 284
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCE--- 452
+ RC P Q +G D++EC C +G C+NT+GS+ C+
Sbjct: 285 SF--RC-RPKLQCKSGFIQDALGN---CIDINECLSISAPCPIGHTCINTEGSYTCQKNV 338
Query: 453 --CPDGYVLAPDGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFT-QGPDQTCV 508
C GY L +G CVD DECA CG G C N+ G + C+C G+ G + CV
Sbjct: 339 PNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV 398
Query: 509 DVDECAE--GRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
DV+EC GR C +C NT GS+ C+C G+ ++ DG C DI+EC P C C
Sbjct: 399 DVNECQRYPGRL-CGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQECA 455
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED--LCSGGVCINTDGSFLCDC-D 623
NV GSY C C GY+ + + CEDI+EC +CS CIN GSF C C
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVT---CEDIDECALPTGGHICSYR-CINIPGSFQCSCPS 511
Query: 624 AGFEPSEDGTDCID 637
+G+ + +G +C D
Sbjct: 512 SGYRLAPNGRNCQD 525
Score = 165 bits (400), Expect = 8e-40
Identities = 94/250 (37%), Positives = 127/250 (50%), Gaps = 22/250 (8%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQC-----GCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
I+EC + C G TC +T + C C GY + C DVDEC+ PC
Sbjct: 309 INECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCG 368
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG--DQRICDHGDCRNTIGSYRCECK 179
+CVN PG+F C C GY C DV+EC R+C H C NT+GSY C C
Sbjct: 369 KGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCS 427
Query: 180 PGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN--DCVDVNE 235
G+ L + C D++ECS P + C N+ G+Y C+C G++ + C D++E
Sbjct: 428 VGFRLSVDGRSCEDINECS-SSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDE 484
Query: 236 CR--EGGMVCRNGRCRNTVGSFRCEC-APGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
C GG +C + RC N GSF+C C + GY L +GRNC+D+DEC H C N +
Sbjct: 485 CALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI--NET 541
Query: 293 CTNTNGGYEC 302
C N G + C
Sbjct: 542 CFNIQGAFRC 551
Score = 151 bits (365), Expect = 1e-35
Identities = 91/247 (36%), Positives = 112/247 (45%), Gaps = 26/247 (10%)
Query: 425 QDLDECRVRPDVC-VGGRCVNTDGSFRCE----CPDGYVLAPDGLSCVDADECALDPRIC 479
+D++EC C +G C+NT GSFRC+ C GY L D SC D DEC C
Sbjct: 215 EDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNC 273
Query: 480 -GNGTCSNTRGGYEC----QCSPGFTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFR 532
+ C NT G + C QC GF Q C+D++EC A C C NT GS+
Sbjct: 274 LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 533 C-----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSA 585
C C GY + +G C D+DEC C H C N GS+ C+C GY
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 586 PQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYR 645
+ C D+NEC+ G C NT GS+LC C GF S DG C D C
Sbjct: 394 SR----MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED--INECSS 447
Query: 646 SLVSGRC 652
S S C
Sbjct: 448 SPCSQEC 454
Score = 136 bits (328), Expect = 4e-31
Identities = 90/266 (33%), Positives = 122/266 (45%), Gaps = 33/266 (12%)
Query: 416 GGMGRPNLTQDLDECRVRP---DVCVGG-----RCVNTDGSFRCECPDGYVLAPDGLSCV 467
GG+ + +++E + P D C GG +C +T C C GY L DG+SC
Sbjct: 156 GGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCE 215
Query: 468 DADECALDPRICGNG-TCSNTRGGYECQ----CSPGFTQGPDQTCVDVDECAEGRASC-- 520
D +EC C G +C NT G + CQ C G+ D +C D+DEC G +C
Sbjct: 216 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLP 275
Query: 521 TFRCHNTAGSFRC----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC 574
F C NT GSFRC C G+ A G +C DI+EC+ CP H C N GSY C
Sbjct: 276 DFICQNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTC 334
Query: 575 K-----CPEGYRRTSAPQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFEP 628
+ C GY + C D++EC + C G C+N+ GSF C+C G+
Sbjct: 335 QKNVPNCGRGYHL----NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 629 SEDGTDCIDRRTGTCYRSLVSG-RCE 653
C+D Y + G +CE
Sbjct: 391 DGISRMCVDVNECQRYPGRLCGHKCE 416
Score = 99.1 bits (236), Expect = 6e-20
Identities = 59/176 (33%), Positives = 85/176 (48%), Gaps = 15/176 (8%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C K G Y + ++ ++EC P C +T + C C G+ C D
Sbjct: 382 CECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED 441
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD--ECEDVDECG---DQRICDH 164
++ECS PC +C N+ G+++C C GY+L+ +D CED+DEC IC +
Sbjct: 442 INECS--SSPC--SQECANVYGSYQCYCRRGYQLS-DVDGVTCEDIDECALPTGGHICSY 496
Query: 165 GDCRNTIGSYRCEC-KPGYTLREN--VCRDVDECSRPRPVCR-NGTCENLPGAYLC 216
C N GS++C C GY L N C+D+DEC C N TC N+ GA+ C
Sbjct: 497 -RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRC 551
Score = 97.9 bits (233), Expect = 1e-19
Identities = 52/118 (44%), Positives = 63/118 (53%), Gaps = 15/118 (12%)
Query: 747 DVDECAAIPG-LCAP------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
DV+EC PG LC G + C C G+R + G C D++EC+ PC Q C N
Sbjct: 399 DVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECAN 456
Query: 798 TDGSYDCLCRTGYEL-DEDGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGY 851
GSY C CR GY+L D DG C D+DEC T H C C N GS++CSC GY
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGY 514
Score = 96.3 bits (229), Expect = 4e-19
Identities = 50/117 (42%), Positives = 61/117 (52%), Gaps = 13/117 (11%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAG--EVCADVDECAVRPPP-CDQLC 795
DVDECA C +PG FRC C GY G +C DV+EC P C C
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 415
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
NT GSY C C G+ L DG +C D++EC + C Q C+N GSY+C C GY+
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQ 470
Score = 81.4 bits (192), Expect = 1e-14
Identities = 43/122 (35%), Positives = 64/122 (52%), Gaps = 15/122 (12%)
Query: 747 DVDECAAIPGL--CAP--GRFRCVCGPGYRPA---GEVCADVDECAVRPPP--CDQLCHN 797
D++EC++ P CA G ++C C GY+ + G C D+DECA+ C C N
Sbjct: 441 DINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 798 TDGSYDCLC-RTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC---SCEDGY 851
GS+ C C +GY L +G NC+D+DEC H C + C N +G++ C C + Y
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENY 560
Query: 852 EK 853
+
Sbjct: 561 RR 562
Score = 75.4 bits (177), Expect = 8e-13
Identities = 47/127 (37%), Positives = 60/127 (47%), Gaps = 22/127 (17%)
Query: 747 DVDECAAIPGLCAP--------GRFRC----VCGPGY-RPAGEVCADVDECAVRPPPCD- 792
D+DEC + C P G FRC C G+ + A C D++EC PC
Sbjct: 262 DIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPI 321
Query: 793 -QLCHNTDGSYDCL-----CRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 844
C NT+GSY C C GY L+E+G C DVDEC C + C N+ GS+
Sbjct: 322 GHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 845 CSCEDGY 851
C C+ GY
Sbjct: 382 CECKTGY 388
Score = 72.1 bits (169), Expect = 8e-12
Identities = 42/101 (41%), Positives = 52/101 (51%), Gaps = 15/101 (14%)
Query: 765 CVCGPGYR--PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCL----CRTGYELDEDG 816
C C GY+ G C DV+EC C + C NT GS+ C C TGYEL ED
Sbjct: 199 CSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN 258
Query: 817 ANCRDVDECERDTHTC--QQICSNTEGSYEC----SCEDGY 851
+ C+D+DECE H C IC NT GS+ C C+ G+
Sbjct: 259 S-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 298
Score = 66.1 bits (154), Expect = 5e-10
Identities = 31/73 (42%), Positives = 40/73 (54%), Gaps = 6/73 (8%)
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 845
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 185 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 846 --SCEDGYEKRGD 856
SC GYE D
Sbjct: 245 DSSCGTGYELTED 257
Score = 60.5 bits (140), Expect = 2e-08
Identities = 50/165 (30%), Positives = 64/165 (38%), Gaps = 20/165 (12%)
Query: 21 YLCCCSVGHAW---GAPCEACPPRGSPAHTALCGEKPGEY---------INPVTNET-KP 67
YLC CSVG G CE S + C G Y ++ V T +
Sbjct: 422 YLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCED 481
Query: 68 IDECDIMP--QLCKPGTCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
IDEC + +C C + P FQC C GY C+D+DEC G C
Sbjct: 482 IDECALPTGGHICS-YRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 540
Query: 125 QCVNLPGAFEC---RCPPGYRLTPSLDECEDVDECGDQRICDHGD 166
C N+ GAF C CP YR + + + E D + C D
Sbjct: 541 TCFNIQGAFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPND 585
>Z98047-1|CAI19628.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 215 bits (526), Expect = 4e-55
Identities = 152/444 (34%), Positives = 208/444 (46%), Gaps = 63/444 (14%)
Query: 193 DECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGR-CRN 250
D C P C+ C + +C C G++ + C DVNEC G CR G C N
Sbjct: 178 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 251 TVGSFRCE----CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC---- 302
TVGSFRC+ C GY LT D +C+D+DEC+ H C D C NT G + C
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDF--ICQNTLGSFRCRPKL 292
Query: 303 SCGAGW--KLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCE-----CPAGWRFDKTA 354
C +G+ +G C+D +EC + C G C N G Y C+ C G+ ++
Sbjct: 293 QCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEG 351
Query: 355 AVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC 414
CVD E G+ HR C S G+ RC F
Sbjct: 352 TRCVDV-DECAPPAEPCGKGHR----------CVNSPGSF------RCECKTGYYF---- 390
Query: 415 QGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECAL 474
G+ R + D++EC+ P G +C NT GS+ C C G+ L+ DG SC D +EC+
Sbjct: 391 -DGISR--MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 475 DPRICGNGTCSNTRGGYECQCSPGF--TQGPDQTCVDVDECA--EGRASCTFRCHNTAGS 530
P C C+N G Y+C C G+ + TC D+DECA G C++RC N GS
Sbjct: 448 SP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 504
Query: 531 FRCTCP-YGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC---KCPEGYRRTS 584
F+C+CP GY +A +G +C+DIDECV C C N+ G + C +CPE YRR++
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSA 564
Query: 585 A--PQDSENACEDINECEEQEDLC 606
A Q+ + I C + C
Sbjct: 565 ATLQQEKTDTVRCIKSCRPNDVTC 588
Score = 208 bits (509), Expect = 5e-53
Identities = 138/407 (33%), Positives = 185/407 (45%), Gaps = 57/407 (14%)
Query: 111 DECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GDQRICDHGD-CR 168
D C G P C+ QC + C C GY+L CEDV+EC C G+ C
Sbjct: 178 DRCRGGGP-CK--QQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCI 234
Query: 169 NTIGSYRCE----CKPGYTLRE-NVCRDVDECSRPRPVCR-NGTCENLPGAYLCH----C 218
NT+GS+RC+ C GY L E N C+D+DEC C + C+N G++ C C
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294
Query: 219 DDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCE-----CAPGYTLTADGRNC 272
GF +C+D+NEC C G C NT GS+ C+ C GY L +G C
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354
Query: 273 RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAG 330
DVDEC PCG+ C N+ G + C C G+ G R CVD +EC+ P G
Sbjct: 355 VDVDECAPPAEPCGKGHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCS 390
+C N G Y+C C G+R C D +E + C + C +
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDGRSCED------INECSSSPCSQE----------CAN 456
Query: 391 EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP--DVCVGGRCVNTDGS 448
++ YC R + + C +D+DEC + +C RC+N GS
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGV-TC----------EDIDECALPTGGHIC-SYRCINIPGS 504
Query: 449 FRCECP-DGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
F+C CP GY LAP+G +C D DEC C N TC N +GG+ C
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 208 bits (507), Expect = 8e-53
Identities = 147/407 (36%), Positives = 199/407 (48%), Gaps = 53/407 (13%)
Query: 234 NECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+ CR GG C+ +CR+T C C GY L +DG +C DV+EC H C R G SC
Sbjct: 178 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC-RLGE-SC 233
Query: 294 TNTNGGYEC----SCGAGWKLV-GRRCVDRDECKELPYVCAGGE-CRNFNGGYVC----E 343
NT G + C SCG G++L C D DEC+ + C C+N G + C +
Sbjct: 234 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
C +G+ D C+D + L + P + C +EG+ C++
Sbjct: 294 CKSGFIQDALGN-CIDINECLSI----------SAPCPIGHT-CINTEGSYT---CQK-N 337
Query: 404 APDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPD 462
P+ + + G D+DEC + C G RCVN+ GSFRCEC GY D
Sbjct: 338 VPNCGRGYHLNEEG----TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF--D 391
Query: 463 GLS--CVDADECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRA 518
G+S CVD +EC P R+CG+ C NT G Y C CS GF D ++C D++EC+ +
Sbjct: 392 GISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS--S 448
Query: 519 SCTFRCHNTAGSFRCTCPYGYAVA-ADGVHCRDIDECVQEP--RVCPHACENVVGSYICK 575
C+ C N GS++C C GY ++ DGV C DIDEC +C + C N+ GS+ C
Sbjct: 449 PCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCS 508
Query: 576 CP-EGYRRTSAPQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
CP GYR AP C+DI+EC CS C N G F C
Sbjct: 509 CPSSGYR--LAPNGRN--CQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 192 bits (469), Expect = 3e-48
Identities = 138/405 (34%), Positives = 175/405 (43%), Gaps = 55/405 (13%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECR- 136
CK C DT C C GY+ + C DV+EC G CR C+N G+F C+
Sbjct: 186 CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 137 ---CPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIGSYRC----ECKPGYTLRE- 186
C GY LT + C+D+DEC G C+NT+GS+RC +CK G+
Sbjct: 245 DSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 187 NVCRDVDECSRPRPVCRNG-TCENLPGAYLC-----HCDDGFKAGPNND-CVDVNECREG 239
C D++EC C G TC N G+Y C +C G+ CVDV+EC
Sbjct: 304 GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPP 363
Query: 240 GMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
C G RC N+ GSFRCEC GY R C DV+EC P GR C NT G
Sbjct: 364 AEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYP---GRLCGHKCENTLG 420
Query: 299 GYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
Y CSC G++L GR C D +EC P C+ EC N G Y C C G++ V
Sbjct: 421 SYLCSCSVGFRLSVDGRSCEDINECSSSP--CS-QECANVYGSYQCYCRRGYQLSDVDGV 477
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
++ E C + C G+ +C P S R+
Sbjct: 478 TCEDIDE----------CALPTGGHICSYRCINIPGSF------QCSCPSSG--YRLAPN 519
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRC---ECPDGY 457
G QD+DEC C + C N G FRC ECP+ Y
Sbjct: 520 GRN----CQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 175 bits (427), Expect = 4e-43
Identities = 127/374 (33%), Positives = 174/374 (46%), Gaps = 52/374 (13%)
Query: 287 RDGNP---SCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGE-CRNFNGGY 340
R G P C +T CSC G++L+ G C D +EC + C GE C N G +
Sbjct: 181 RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 240
Query: 341 VCE----CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWG 396
C+ C G+ + + C D DE E+G + P+ C G
Sbjct: 241 RCQRDSSCGTGYELTEDNS-CKD------IDECESG-------IHNCLPDFICQN--TLG 284
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCE--- 452
+ RC P Q +G D++EC C +G C+NT+GS+ C+
Sbjct: 285 SF--RC-RPKLQCKSGFIQDALGN---CIDINECLSISAPCPIGHTCINTEGSYTCQKNV 338
Query: 453 --CPDGYVLAPDGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFT-QGPDQTCV 508
C GY L +G CVD DECA CG G C N+ G + C+C G+ G + CV
Sbjct: 339 PNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV 398
Query: 509 DVDECAE--GRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
DV+EC GR C +C NT GS+ C+C G+ ++ DG C DI+EC P C C
Sbjct: 399 DVNECQRYPGRL-CGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQECA 455
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED--LCSGGVCINTDGSFLCDC-D 623
NV GSY C C GY+ + + CEDI+EC +CS CIN GSF C C
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVT---CEDIDECALPTGGHICSYR-CINIPGSFQCSCPS 511
Query: 624 AGFEPSEDGTDCID 637
+G+ + +G +C D
Sbjct: 512 SGYRLAPNGRNCQD 525
Score = 167 bits (406), Expect = 1e-40
Identities = 95/250 (38%), Positives = 128/250 (51%), Gaps = 22/250 (8%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQC-----GCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
I+EC + C G TC +T + C C GY + C DVDEC+ PC
Sbjct: 309 INECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCG 368
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG--DQRICDHGDCRNTIGSYRCECK 179
+CVN PG+F C C GY C DV+EC R+C H C NT+GSY C C
Sbjct: 369 KGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCS 427
Query: 180 PGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN--DCVDVNE 235
G+ L + C D++ECS P + C N+ G+Y C+C G++ + C D++E
Sbjct: 428 VGFRLSVDGRSCEDINECS-SSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDE 484
Query: 236 CR--EGGMVCRNGRCRNTVGSFRCEC-APGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
C GG +C + RC N GSF+C C + GY L +GRNC+D+DEC H C N +
Sbjct: 485 CALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI--NET 541
Query: 293 CTNTNGGYEC 302
C N GG+ C
Sbjct: 542 CFNIQGGFRC 551
Score = 151 bits (365), Expect = 1e-35
Identities = 91/247 (36%), Positives = 112/247 (45%), Gaps = 26/247 (10%)
Query: 425 QDLDECRVRPDVC-VGGRCVNTDGSFRCE----CPDGYVLAPDGLSCVDADECALDPRIC 479
+D++EC C +G C+NT GSFRC+ C GY L D SC D DEC C
Sbjct: 215 EDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNC 273
Query: 480 -GNGTCSNTRGGYEC----QCSPGFTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFR 532
+ C NT G + C QC GF Q C+D++EC A C C NT GS+
Sbjct: 274 LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 533 C-----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSA 585
C C GY + +G C D+DEC C H C N GS+ C+C GY
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 586 PQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYR 645
+ C D+NEC+ G C NT GS+LC C GF S DG C D C
Sbjct: 394 SR----MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED--INECSS 447
Query: 646 SLVSGRC 652
S S C
Sbjct: 448 SPCSQEC 454
Score = 136 bits (328), Expect = 4e-31
Identities = 90/266 (33%), Positives = 122/266 (45%), Gaps = 33/266 (12%)
Query: 416 GGMGRPNLTQDLDECRVRP---DVCVGG-----RCVNTDGSFRCECPDGYVLAPDGLSCV 467
GG+ + +++E + P D C GG +C +T C C GY L DG+SC
Sbjct: 156 GGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCE 215
Query: 468 DADECALDPRICGNG-TCSNTRGGYECQ----CSPGFTQGPDQTCVDVDECAEGRASC-- 520
D +EC C G +C NT G + CQ C G+ D +C D+DEC G +C
Sbjct: 216 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLP 275
Query: 521 TFRCHNTAGSFRC----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC 574
F C NT GSFRC C G+ A G +C DI+EC+ CP H C N GSY C
Sbjct: 276 DFICQNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTC 334
Query: 575 K-----CPEGYRRTSAPQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFEP 628
+ C GY + C D++EC + C G C+N+ GSF C+C G+
Sbjct: 335 QKNVPNCGRGYHL----NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 629 SEDGTDCIDRRTGTCYRSLVSG-RCE 653
C+D Y + G +CE
Sbjct: 391 DGISRMCVDVNECQRYPGRLCGHKCE 416
Score = 97.9 bits (233), Expect = 1e-19
Identities = 52/118 (44%), Positives = 63/118 (53%), Gaps = 15/118 (12%)
Query: 747 DVDECAAIPG-LCAP------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
DV+EC PG LC G + C C G+R + G C D++EC+ PC Q C N
Sbjct: 399 DVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECAN 456
Query: 798 TDGSYDCLCRTGYEL-DEDGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGY 851
GSY C CR GY+L D DG C D+DEC T H C C N GS++CSC GY
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGY 514
Score = 97.5 bits (232), Expect = 2e-19
Identities = 58/176 (32%), Positives = 84/176 (47%), Gaps = 15/176 (8%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C K G Y + ++ ++EC P C +T + C C G+ C D
Sbjct: 382 CECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED 441
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD--ECEDVDECG---DQRICDH 164
++ECS PC +C N+ G+++C C GY+L+ +D CED+DEC IC +
Sbjct: 442 INECS--SSPC--SQECANVYGSYQCYCRRGYQLS-DVDGVTCEDIDECALPTGGHICSY 496
Query: 165 GDCRNTIGSYRCEC-KPGYTLREN--VCRDVDECSRPRPVCR-NGTCENLPGAYLC 216
C N GS++C C GY L N C+D+DEC C N TC N+ G + C
Sbjct: 497 -RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 96.3 bits (229), Expect = 4e-19
Identities = 50/117 (42%), Positives = 61/117 (52%), Gaps = 13/117 (11%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAG--EVCADVDECAVRPPP-CDQLC 795
DVDECA C +PG FRC C GY G +C DV+EC P C C
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 415
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
NT GSY C C G+ L DG +C D++EC + C Q C+N GSY+C C GY+
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQ 470
Score = 81.0 bits (191), Expect = 2e-14
Identities = 43/122 (35%), Positives = 63/122 (51%), Gaps = 15/122 (12%)
Query: 747 DVDECAAIPGL--CAP--GRFRCVCGPGYRPA---GEVCADVDECAVRPPP--CDQLCHN 797
D++EC++ P CA G ++C C GY+ + G C D+DECA+ C C N
Sbjct: 441 DINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 798 TDGSYDCLC-RTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC---SCEDGY 851
GS+ C C +GY L +G NC+D+DEC H C + C N +G + C C + Y
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Query: 852 EK 853
+
Sbjct: 561 RR 562
Score = 75.4 bits (177), Expect = 8e-13
Identities = 47/127 (37%), Positives = 60/127 (47%), Gaps = 22/127 (17%)
Query: 747 DVDECAAIPGLCAP--------GRFRC----VCGPGY-RPAGEVCADVDECAVRPPPCD- 792
D+DEC + C P G FRC C G+ + A C D++EC PC
Sbjct: 262 DIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPI 321
Query: 793 -QLCHNTDGSYDCL-----CRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 844
C NT+GSY C C GY L+E+G C DVDEC C + C N+ GS+
Sbjct: 322 GHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 845 CSCEDGY 851
C C+ GY
Sbjct: 382 CECKTGY 388
Score = 72.1 bits (169), Expect = 8e-12
Identities = 42/101 (41%), Positives = 52/101 (51%), Gaps = 15/101 (14%)
Query: 765 CVCGPGYR--PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCL----CRTGYELDEDG 816
C C GY+ G C DV+EC C + C NT GS+ C C TGYEL ED
Sbjct: 199 CSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN 258
Query: 817 ANCRDVDECERDTHTC--QQICSNTEGSYEC----SCEDGY 851
+ C+D+DECE H C IC NT GS+ C C+ G+
Sbjct: 259 S-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 298
Score = 66.1 bits (154), Expect = 5e-10
Identities = 31/73 (42%), Positives = 40/73 (54%), Gaps = 6/73 (8%)
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 845
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 185 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 846 --SCEDGYEKRGD 856
SC GYE D
Sbjct: 245 DSSCGTGYELTED 257
Score = 58.8 bits (136), Expect = 8e-08
Identities = 49/165 (29%), Positives = 63/165 (38%), Gaps = 20/165 (12%)
Query: 21 YLCCCSVGHAW---GAPCEACPPRGSPAHTALCGEKPGEY---------INPVTNET-KP 67
YLC CSVG G CE S + C G Y ++ V T +
Sbjct: 422 YLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCED 481
Query: 68 IDECDIMP--QLCKPGTCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
IDEC + +C C + P FQC C GY C+D+DEC G C
Sbjct: 482 IDECALPTGGHICS-YRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 540
Query: 125 QCVNLPGAFEC---RCPPGYRLTPSLDECEDVDECGDQRICDHGD 166
C N+ G F C CP YR + + + E D + C D
Sbjct: 541 TCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPND 585
>Z95331-3|CAI41717.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 215 bits (526), Expect = 4e-55
Identities = 152/444 (34%), Positives = 208/444 (46%), Gaps = 63/444 (14%)
Query: 193 DECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGR-CRN 250
D C P C+ C + +C C G++ + C DVNEC G CR G C N
Sbjct: 178 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 251 TVGSFRCE----CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC---- 302
TVGSFRC+ C GY LT D +C+D+DEC+ H C D C NT G + C
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDF--ICQNTLGSFRCRPKL 292
Query: 303 SCGAGW--KLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCE-----CPAGWRFDKTA 354
C +G+ +G C+D +EC + C G C N G Y C+ C G+ ++
Sbjct: 293 QCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEG 351
Query: 355 AVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC 414
CVD E G+ HR C S G+ RC F
Sbjct: 352 TRCVDV-DECAPPAEPCGKGHR----------CVNSPGSF------RCECKTGYYF---- 390
Query: 415 QGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECAL 474
G+ R + D++EC+ P G +C NT GS+ C C G+ L+ DG SC D +EC+
Sbjct: 391 -DGISR--MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 475 DPRICGNGTCSNTRGGYECQCSPGF--TQGPDQTCVDVDECA--EGRASCTFRCHNTAGS 530
P C C+N G Y+C C G+ + TC D+DECA G C++RC N GS
Sbjct: 448 SP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 504
Query: 531 FRCTCP-YGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC---KCPEGYRRTS 584
F+C+CP GY +A +G +C+DIDECV C C N+ G + C +CPE YRR++
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSA 564
Query: 585 A--PQDSENACEDINECEEQEDLC 606
A Q+ + I C + C
Sbjct: 565 ATLQQEKTDTVRCIKSCRPNDVTC 588
Score = 208 bits (509), Expect = 5e-53
Identities = 138/407 (33%), Positives = 185/407 (45%), Gaps = 57/407 (14%)
Query: 111 DECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GDQRICDHGD-CR 168
D C G P C+ QC + C C GY+L CEDV+EC C G+ C
Sbjct: 178 DRCRGGGP-CK--QQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCI 234
Query: 169 NTIGSYRCE----CKPGYTLRE-NVCRDVDECSRPRPVCR-NGTCENLPGAYLCH----C 218
NT+GS+RC+ C GY L E N C+D+DEC C + C+N G++ C C
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294
Query: 219 DDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCE-----CAPGYTLTADGRNC 272
GF +C+D+NEC C G C NT GS+ C+ C GY L +G C
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354
Query: 273 RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAG 330
DVDEC PCG+ C N+ G + C C G+ G R CVD +EC+ P G
Sbjct: 355 VDVDECAPPAEPCGKGHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCS 390
+C N G Y+C C G+R C D +E + C + C +
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDGRSCED------INECSSSPCSQE----------CAN 456
Query: 391 EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP--DVCVGGRCVNTDGS 448
++ YC R + + C +D+DEC + +C RC+N GS
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGV-TC----------EDIDECALPTGGHIC-SYRCINIPGS 504
Query: 449 FRCECP-DGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
F+C CP GY LAP+G +C D DEC C N TC N +GG+ C
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 208 bits (507), Expect = 8e-53
Identities = 147/407 (36%), Positives = 199/407 (48%), Gaps = 53/407 (13%)
Query: 234 NECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+ CR GG C+ +CR+T C C GY L +DG +C DV+EC H C R G SC
Sbjct: 178 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC-RLGE-SC 233
Query: 294 TNTNGGYEC----SCGAGWKLV-GRRCVDRDECKELPYVCAGGE-CRNFNGGYVC----E 343
NT G + C SCG G++L C D DEC+ + C C+N G + C +
Sbjct: 234 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
C +G+ D C+D + L + P + C +EG+ C++
Sbjct: 294 CKSGFIQDALGN-CIDINECLSI----------SAPCPIGHT-CINTEGSYT---CQK-N 337
Query: 404 APDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPD 462
P+ + + G D+DEC + C G RCVN+ GSFRCEC GY D
Sbjct: 338 VPNCGRGYHLNEEG----TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF--D 391
Query: 463 GLS--CVDADECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRA 518
G+S CVD +EC P R+CG+ C NT G Y C CS GF D ++C D++EC+ +
Sbjct: 392 GISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS--S 448
Query: 519 SCTFRCHNTAGSFRCTCPYGYAVA-ADGVHCRDIDECVQEP--RVCPHACENVVGSYICK 575
C+ C N GS++C C GY ++ DGV C DIDEC +C + C N+ GS+ C
Sbjct: 449 PCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCS 508
Query: 576 CP-EGYRRTSAPQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
CP GYR AP C+DI+EC CS C N G F C
Sbjct: 509 CPSSGYR--LAPNGRN--CQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 192 bits (469), Expect = 3e-48
Identities = 138/405 (34%), Positives = 175/405 (43%), Gaps = 55/405 (13%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECR- 136
CK C DT C C GY+ + C DV+EC G CR C+N G+F C+
Sbjct: 186 CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 137 ---CPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIGSYRC----ECKPGYTLRE- 186
C GY LT + C+D+DEC G C+NT+GS+RC +CK G+
Sbjct: 245 DSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 187 NVCRDVDECSRPRPVCRNG-TCENLPGAYLC-----HCDDGFKAGPNND-CVDVNECREG 239
C D++EC C G TC N G+Y C +C G+ CVDV+EC
Sbjct: 304 GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPP 363
Query: 240 GMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
C G RC N+ GSFRCEC GY R C DV+EC P GR C NT G
Sbjct: 364 AEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYP---GRLCGHKCENTLG 420
Query: 299 GYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
Y CSC G++L GR C D +EC P C+ EC N G Y C C G++ V
Sbjct: 421 SYLCSCSVGFRLSVDGRSCEDINECSSSP--CS-QECANVYGSYQCYCRRGYQLSDVDGV 477
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
++ E C + C G+ +C P S R+
Sbjct: 478 TCEDIDE----------CALPTGGHICSYRCINIPGSF------QCSCPSSG--YRLAPN 519
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRC---ECPDGY 457
G QD+DEC C + C N G FRC ECP+ Y
Sbjct: 520 GRN----CQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 175 bits (427), Expect = 4e-43
Identities = 127/374 (33%), Positives = 174/374 (46%), Gaps = 52/374 (13%)
Query: 287 RDGNP---SCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGE-CRNFNGGY 340
R G P C +T CSC G++L+ G C D +EC + C GE C N G +
Sbjct: 181 RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 240
Query: 341 VCE----CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWG 396
C+ C G+ + + C D DE E+G + P+ C G
Sbjct: 241 RCQRDSSCGTGYELTEDNS-CKD------IDECESG-------IHNCLPDFICQN--TLG 284
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCE--- 452
+ RC P Q +G D++EC C +G C+NT+GS+ C+
Sbjct: 285 SF--RC-RPKLQCKSGFIQDALGN---CIDINECLSISAPCPIGHTCINTEGSYTCQKNV 338
Query: 453 --CPDGYVLAPDGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFT-QGPDQTCV 508
C GY L +G CVD DECA CG G C N+ G + C+C G+ G + CV
Sbjct: 339 PNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV 398
Query: 509 DVDECAE--GRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
DV+EC GR C +C NT GS+ C+C G+ ++ DG C DI+EC P C C
Sbjct: 399 DVNECQRYPGRL-CGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQECA 455
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED--LCSGGVCINTDGSFLCDC-D 623
NV GSY C C GY+ + + CEDI+EC +CS CIN GSF C C
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVT---CEDIDECALPTGGHICSYR-CINIPGSFQCSCPS 511
Query: 624 AGFEPSEDGTDCID 637
+G+ + +G +C D
Sbjct: 512 SGYRLAPNGRNCQD 525
Score = 167 bits (406), Expect = 1e-40
Identities = 95/250 (38%), Positives = 128/250 (51%), Gaps = 22/250 (8%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQC-----GCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
I+EC + C G TC +T + C C GY + C DVDEC+ PC
Sbjct: 309 INECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCG 368
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG--DQRICDHGDCRNTIGSYRCECK 179
+CVN PG+F C C GY C DV+EC R+C H C NT+GSY C C
Sbjct: 369 KGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCS 427
Query: 180 PGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN--DCVDVNE 235
G+ L + C D++ECS P + C N+ G+Y C+C G++ + C D++E
Sbjct: 428 VGFRLSVDGRSCEDINECS-SSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDE 484
Query: 236 CR--EGGMVCRNGRCRNTVGSFRCEC-APGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
C GG +C + RC N GSF+C C + GY L +GRNC+D+DEC H C N +
Sbjct: 485 CALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI--NET 541
Query: 293 CTNTNGGYEC 302
C N GG+ C
Sbjct: 542 CFNIQGGFRC 551
Score = 151 bits (365), Expect = 1e-35
Identities = 91/247 (36%), Positives = 112/247 (45%), Gaps = 26/247 (10%)
Query: 425 QDLDECRVRPDVC-VGGRCVNTDGSFRCE----CPDGYVLAPDGLSCVDADECALDPRIC 479
+D++EC C +G C+NT GSFRC+ C GY L D SC D DEC C
Sbjct: 215 EDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNC 273
Query: 480 -GNGTCSNTRGGYEC----QCSPGFTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFR 532
+ C NT G + C QC GF Q C+D++EC A C C NT GS+
Sbjct: 274 LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 533 C-----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSA 585
C C GY + +G C D+DEC C H C N GS+ C+C GY
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 586 PQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYR 645
+ C D+NEC+ G C NT GS+LC C GF S DG C D C
Sbjct: 394 SR----MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED--INECSS 447
Query: 646 SLVSGRC 652
S S C
Sbjct: 448 SPCSQEC 454
Score = 136 bits (328), Expect = 4e-31
Identities = 90/266 (33%), Positives = 122/266 (45%), Gaps = 33/266 (12%)
Query: 416 GGMGRPNLTQDLDECRVRP---DVCVGG-----RCVNTDGSFRCECPDGYVLAPDGLSCV 467
GG+ + +++E + P D C GG +C +T C C GY L DG+SC
Sbjct: 156 GGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCE 215
Query: 468 DADECALDPRICGNG-TCSNTRGGYECQ----CSPGFTQGPDQTCVDVDECAEGRASC-- 520
D +EC C G +C NT G + CQ C G+ D +C D+DEC G +C
Sbjct: 216 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLP 275
Query: 521 TFRCHNTAGSFRC----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC 574
F C NT GSFRC C G+ A G +C DI+EC+ CP H C N GSY C
Sbjct: 276 DFICQNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTC 334
Query: 575 K-----CPEGYRRTSAPQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFEP 628
+ C GY + C D++EC + C G C+N+ GSF C+C G+
Sbjct: 335 QKNVPNCGRGYHL----NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 629 SEDGTDCIDRRTGTCYRSLVSG-RCE 653
C+D Y + G +CE
Sbjct: 391 DGISRMCVDVNECQRYPGRLCGHKCE 416
Score = 97.9 bits (233), Expect = 1e-19
Identities = 52/118 (44%), Positives = 63/118 (53%), Gaps = 15/118 (12%)
Query: 747 DVDECAAIPG-LCAP------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
DV+EC PG LC G + C C G+R + G C D++EC+ PC Q C N
Sbjct: 399 DVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECAN 456
Query: 798 TDGSYDCLCRTGYEL-DEDGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGY 851
GSY C CR GY+L D DG C D+DEC T H C C N GS++CSC GY
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGY 514
Score = 97.5 bits (232), Expect = 2e-19
Identities = 58/176 (32%), Positives = 84/176 (47%), Gaps = 15/176 (8%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C K G Y + ++ ++EC P C +T + C C G+ C D
Sbjct: 382 CECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED 441
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD--ECEDVDECG---DQRICDH 164
++ECS PC +C N+ G+++C C GY+L+ +D CED+DEC IC +
Sbjct: 442 INECS--SSPC--SQECANVYGSYQCYCRRGYQLS-DVDGVTCEDIDECALPTGGHICSY 496
Query: 165 GDCRNTIGSYRCEC-KPGYTLREN--VCRDVDECSRPRPVCR-NGTCENLPGAYLC 216
C N GS++C C GY L N C+D+DEC C N TC N+ G + C
Sbjct: 497 -RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 96.3 bits (229), Expect = 4e-19
Identities = 50/117 (42%), Positives = 61/117 (52%), Gaps = 13/117 (11%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAG--EVCADVDECAVRPPP-CDQLC 795
DVDECA C +PG FRC C GY G +C DV+EC P C C
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 415
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
NT GSY C C G+ L DG +C D++EC + C Q C+N GSY+C C GY+
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQ 470
Score = 81.0 bits (191), Expect = 2e-14
Identities = 43/122 (35%), Positives = 63/122 (51%), Gaps = 15/122 (12%)
Query: 747 DVDECAAIPGL--CAP--GRFRCVCGPGYRPA---GEVCADVDECAVRPPP--CDQLCHN 797
D++EC++ P CA G ++C C GY+ + G C D+DECA+ C C N
Sbjct: 441 DINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 798 TDGSYDCLC-RTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC---SCEDGY 851
GS+ C C +GY L +G NC+D+DEC H C + C N +G + C C + Y
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Query: 852 EK 853
+
Sbjct: 561 RR 562
Score = 75.4 bits (177), Expect = 8e-13
Identities = 47/127 (37%), Positives = 60/127 (47%), Gaps = 22/127 (17%)
Query: 747 DVDECAAIPGLCAP--------GRFRC----VCGPGY-RPAGEVCADVDECAVRPPPCD- 792
D+DEC + C P G FRC C G+ + A C D++EC PC
Sbjct: 262 DIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPI 321
Query: 793 -QLCHNTDGSYDCL-----CRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 844
C NT+GSY C C GY L+E+G C DVDEC C + C N+ GS+
Sbjct: 322 GHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 845 CSCEDGY 851
C C+ GY
Sbjct: 382 CECKTGY 388
Score = 72.1 bits (169), Expect = 8e-12
Identities = 42/101 (41%), Positives = 52/101 (51%), Gaps = 15/101 (14%)
Query: 765 CVCGPGYR--PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCL----CRTGYELDEDG 816
C C GY+ G C DV+EC C + C NT GS+ C C TGYEL ED
Sbjct: 199 CSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN 258
Query: 817 ANCRDVDECERDTHTC--QQICSNTEGSYEC----SCEDGY 851
+ C+D+DECE H C IC NT GS+ C C+ G+
Sbjct: 259 S-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 298
Score = 66.1 bits (154), Expect = 5e-10
Identities = 31/73 (42%), Positives = 40/73 (54%), Gaps = 6/73 (8%)
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 845
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 185 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 846 --SCEDGYEKRGD 856
SC GYE D
Sbjct: 245 DSSCGTGYELTED 257
Score = 58.8 bits (136), Expect = 8e-08
Identities = 49/165 (29%), Positives = 63/165 (38%), Gaps = 20/165 (12%)
Query: 21 YLCCCSVGHAW---GAPCEACPPRGSPAHTALCGEKPGEY---------INPVTNET-KP 67
YLC CSVG G CE S + C G Y ++ V T +
Sbjct: 422 YLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCED 481
Query: 68 IDECDIMP--QLCKPGTCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
IDEC + +C C + P FQC C GY C+D+DEC G C
Sbjct: 482 IDECALPTGGHICS-YRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 540
Query: 125 QCVNLPGAFEC---RCPPGYRLTPSLDECEDVDECGDQRICDHGD 166
C N+ G F C CP YR + + + E D + C D
Sbjct: 541 TCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPND 585
>AL021391-3|CAI18930.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 215 bits (526), Expect = 4e-55
Identities = 152/444 (34%), Positives = 208/444 (46%), Gaps = 63/444 (14%)
Query: 193 DECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGR-CRN 250
D C P C+ C + +C C G++ + C DVNEC G CR G C N
Sbjct: 178 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 251 TVGSFRCE----CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC---- 302
TVGSFRC+ C GY LT D +C+D+DEC+ H C D C NT G + C
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDF--ICQNTLGSFRCRPKL 292
Query: 303 SCGAGW--KLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCE-----CPAGWRFDKTA 354
C +G+ +G C+D +EC + C G C N G Y C+ C G+ ++
Sbjct: 293 QCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEG 351
Query: 355 AVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC 414
CVD E G+ HR C S G+ RC F
Sbjct: 352 TRCVDV-DECAPPAEPCGKGHR----------CVNSPGSF------RCECKTGYYF---- 390
Query: 415 QGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECAL 474
G+ R + D++EC+ P G +C NT GS+ C C G+ L+ DG SC D +EC+
Sbjct: 391 -DGISR--MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 475 DPRICGNGTCSNTRGGYECQCSPGF--TQGPDQTCVDVDECA--EGRASCTFRCHNTAGS 530
P C C+N G Y+C C G+ + TC D+DECA G C++RC N GS
Sbjct: 448 SP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 504
Query: 531 FRCTCP-YGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC---KCPEGYRRTS 584
F+C+CP GY +A +G +C+DIDECV C C N+ G + C +CPE YRR++
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSA 564
Query: 585 A--PQDSENACEDINECEEQEDLC 606
A Q+ + I C + C
Sbjct: 565 ATLQQEKTDTVRCIKSCRPNDVTC 588
Score = 208 bits (509), Expect = 5e-53
Identities = 138/407 (33%), Positives = 185/407 (45%), Gaps = 57/407 (14%)
Query: 111 DECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GDQRICDHGD-CR 168
D C G P C+ QC + C C GY+L CEDV+EC C G+ C
Sbjct: 178 DRCRGGGP-CK--QQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCI 234
Query: 169 NTIGSYRCE----CKPGYTLRE-NVCRDVDECSRPRPVCR-NGTCENLPGAYLCH----C 218
NT+GS+RC+ C GY L E N C+D+DEC C + C+N G++ C C
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294
Query: 219 DDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCE-----CAPGYTLTADGRNC 272
GF +C+D+NEC C G C NT GS+ C+ C GY L +G C
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354
Query: 273 RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAG 330
DVDEC PCG+ C N+ G + C C G+ G R CVD +EC+ P G
Sbjct: 355 VDVDECAPPAEPCGKGHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCS 390
+C N G Y+C C G+R C D +E + C + C +
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDGRSCED------INECSSSPCSQE----------CAN 456
Query: 391 EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP--DVCVGGRCVNTDGS 448
++ YC R + + C +D+DEC + +C RC+N GS
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGV-TC----------EDIDECALPTGGHIC-SYRCINIPGS 504
Query: 449 FRCECP-DGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
F+C CP GY LAP+G +C D DEC C N TC N +GG+ C
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 208 bits (507), Expect = 8e-53
Identities = 147/407 (36%), Positives = 199/407 (48%), Gaps = 53/407 (13%)
Query: 234 NECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+ CR GG C+ +CR+T C C GY L +DG +C DV+EC H C R G SC
Sbjct: 178 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC-RLGE-SC 233
Query: 294 TNTNGGYEC----SCGAGWKLV-GRRCVDRDECKELPYVCAGGE-CRNFNGGYVC----E 343
NT G + C SCG G++L C D DEC+ + C C+N G + C +
Sbjct: 234 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
C +G+ D C+D + L + P + C +EG+ C++
Sbjct: 294 CKSGFIQDALGN-CIDINECLSI----------SAPCPIGHT-CINTEGSYT---CQK-N 337
Query: 404 APDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPD 462
P+ + + G D+DEC + C G RCVN+ GSFRCEC GY D
Sbjct: 338 VPNCGRGYHLNEEG----TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF--D 391
Query: 463 GLS--CVDADECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRA 518
G+S CVD +EC P R+CG+ C NT G Y C CS GF D ++C D++EC+ +
Sbjct: 392 GISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS--S 448
Query: 519 SCTFRCHNTAGSFRCTCPYGYAVA-ADGVHCRDIDECVQEP--RVCPHACENVVGSYICK 575
C+ C N GS++C C GY ++ DGV C DIDEC +C + C N+ GS+ C
Sbjct: 449 PCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCS 508
Query: 576 CP-EGYRRTSAPQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
CP GYR AP C+DI+EC CS C N G F C
Sbjct: 509 CPSSGYR--LAPNGRN--CQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 192 bits (469), Expect = 3e-48
Identities = 138/405 (34%), Positives = 175/405 (43%), Gaps = 55/405 (13%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECR- 136
CK C DT C C GY+ + C DV+EC G CR C+N G+F C+
Sbjct: 186 CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 137 ---CPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIGSYRC----ECKPGYTLRE- 186
C GY LT + C+D+DEC G C+NT+GS+RC +CK G+
Sbjct: 245 DSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 187 NVCRDVDECSRPRPVCRNG-TCENLPGAYLC-----HCDDGFKAGPNND-CVDVNECREG 239
C D++EC C G TC N G+Y C +C G+ CVDV+EC
Sbjct: 304 GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPP 363
Query: 240 GMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
C G RC N+ GSFRCEC GY R C DV+EC P GR C NT G
Sbjct: 364 AEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYP---GRLCGHKCENTLG 420
Query: 299 GYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
Y CSC G++L GR C D +EC P C+ EC N G Y C C G++ V
Sbjct: 421 SYLCSCSVGFRLSVDGRSCEDINECSSSP--CS-QECANVYGSYQCYCRRGYQLSDVDGV 477
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
++ E C + C G+ +C P S R+
Sbjct: 478 TCEDIDE----------CALPTGGHICSYRCINIPGSF------QCSCPSSG--YRLAPN 519
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRC---ECPDGY 457
G QD+DEC C + C N G FRC ECP+ Y
Sbjct: 520 GRN----CQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 175 bits (427), Expect = 4e-43
Identities = 127/374 (33%), Positives = 174/374 (46%), Gaps = 52/374 (13%)
Query: 287 RDGNP---SCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGE-CRNFNGGY 340
R G P C +T CSC G++L+ G C D +EC + C GE C N G +
Sbjct: 181 RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 240
Query: 341 VCE----CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWG 396
C+ C G+ + + C D DE E+G + P+ C G
Sbjct: 241 RCQRDSSCGTGYELTEDNS-CKD------IDECESG-------IHNCLPDFICQN--TLG 284
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCE--- 452
+ RC P Q +G D++EC C +G C+NT+GS+ C+
Sbjct: 285 SF--RC-RPKLQCKSGFIQDALGN---CIDINECLSISAPCPIGHTCINTEGSYTCQKNV 338
Query: 453 --CPDGYVLAPDGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFT-QGPDQTCV 508
C GY L +G CVD DECA CG G C N+ G + C+C G+ G + CV
Sbjct: 339 PNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV 398
Query: 509 DVDECAE--GRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
DV+EC GR C +C NT GS+ C+C G+ ++ DG C DI+EC P C C
Sbjct: 399 DVNECQRYPGRL-CGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQECA 455
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED--LCSGGVCINTDGSFLCDC-D 623
NV GSY C C GY+ + + CEDI+EC +CS CIN GSF C C
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVT---CEDIDECALPTGGHICSYR-CINIPGSFQCSCPS 511
Query: 624 AGFEPSEDGTDCID 637
+G+ + +G +C D
Sbjct: 512 SGYRLAPNGRNCQD 525
Score = 167 bits (406), Expect = 1e-40
Identities = 95/250 (38%), Positives = 128/250 (51%), Gaps = 22/250 (8%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQC-----GCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
I+EC + C G TC +T + C C GY + C DVDEC+ PC
Sbjct: 309 INECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCG 368
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG--DQRICDHGDCRNTIGSYRCECK 179
+CVN PG+F C C GY C DV+EC R+C H C NT+GSY C C
Sbjct: 369 KGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCS 427
Query: 180 PGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN--DCVDVNE 235
G+ L + C D++ECS P + C N+ G+Y C+C G++ + C D++E
Sbjct: 428 VGFRLSVDGRSCEDINECS-SSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDE 484
Query: 236 CR--EGGMVCRNGRCRNTVGSFRCEC-APGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
C GG +C + RC N GSF+C C + GY L +GRNC+D+DEC H C N +
Sbjct: 485 CALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI--NET 541
Query: 293 CTNTNGGYEC 302
C N GG+ C
Sbjct: 542 CFNIQGGFRC 551
Score = 151 bits (365), Expect = 1e-35
Identities = 91/247 (36%), Positives = 112/247 (45%), Gaps = 26/247 (10%)
Query: 425 QDLDECRVRPDVC-VGGRCVNTDGSFRCE----CPDGYVLAPDGLSCVDADECALDPRIC 479
+D++EC C +G C+NT GSFRC+ C GY L D SC D DEC C
Sbjct: 215 EDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNC 273
Query: 480 -GNGTCSNTRGGYEC----QCSPGFTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFR 532
+ C NT G + C QC GF Q C+D++EC A C C NT GS+
Sbjct: 274 LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 533 C-----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSA 585
C C GY + +G C D+DEC C H C N GS+ C+C GY
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 586 PQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYR 645
+ C D+NEC+ G C NT GS+LC C GF S DG C D C
Sbjct: 394 SR----MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED--INECSS 447
Query: 646 SLVSGRC 652
S S C
Sbjct: 448 SPCSQEC 454
Score = 136 bits (328), Expect = 4e-31
Identities = 90/266 (33%), Positives = 122/266 (45%), Gaps = 33/266 (12%)
Query: 416 GGMGRPNLTQDLDECRVRP---DVCVGG-----RCVNTDGSFRCECPDGYVLAPDGLSCV 467
GG+ + +++E + P D C GG +C +T C C GY L DG+SC
Sbjct: 156 GGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCE 215
Query: 468 DADECALDPRICGNG-TCSNTRGGYECQ----CSPGFTQGPDQTCVDVDECAEGRASC-- 520
D +EC C G +C NT G + CQ C G+ D +C D+DEC G +C
Sbjct: 216 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLP 275
Query: 521 TFRCHNTAGSFRC----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC 574
F C NT GSFRC C G+ A G +C DI+EC+ CP H C N GSY C
Sbjct: 276 DFICQNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTC 334
Query: 575 K-----CPEGYRRTSAPQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFEP 628
+ C GY + C D++EC + C G C+N+ GSF C+C G+
Sbjct: 335 QKNVPNCGRGYHL----NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 629 SEDGTDCIDRRTGTCYRSLVSG-RCE 653
C+D Y + G +CE
Sbjct: 391 DGISRMCVDVNECQRYPGRLCGHKCE 416
Score = 97.9 bits (233), Expect = 1e-19
Identities = 52/118 (44%), Positives = 63/118 (53%), Gaps = 15/118 (12%)
Query: 747 DVDECAAIPG-LCAP------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
DV+EC PG LC G + C C G+R + G C D++EC+ PC Q C N
Sbjct: 399 DVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECAN 456
Query: 798 TDGSYDCLCRTGYEL-DEDGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGY 851
GSY C CR GY+L D DG C D+DEC T H C C N GS++CSC GY
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGY 514
Score = 97.5 bits (232), Expect = 2e-19
Identities = 58/176 (32%), Positives = 84/176 (47%), Gaps = 15/176 (8%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C K G Y + ++ ++EC P C +T + C C G+ C D
Sbjct: 382 CECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED 441
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD--ECEDVDECG---DQRICDH 164
++ECS PC +C N+ G+++C C GY+L+ +D CED+DEC IC +
Sbjct: 442 INECS--SSPC--SQECANVYGSYQCYCRRGYQLS-DVDGVTCEDIDECALPTGGHICSY 496
Query: 165 GDCRNTIGSYRCEC-KPGYTLREN--VCRDVDECSRPRPVCR-NGTCENLPGAYLC 216
C N GS++C C GY L N C+D+DEC C N TC N+ G + C
Sbjct: 497 -RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 96.3 bits (229), Expect = 4e-19
Identities = 50/117 (42%), Positives = 61/117 (52%), Gaps = 13/117 (11%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAG--EVCADVDECAVRPPP-CDQLC 795
DVDECA C +PG FRC C GY G +C DV+EC P C C
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 415
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
NT GSY C C G+ L DG +C D++EC + C Q C+N GSY+C C GY+
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQ 470
Score = 81.0 bits (191), Expect = 2e-14
Identities = 43/122 (35%), Positives = 63/122 (51%), Gaps = 15/122 (12%)
Query: 747 DVDECAAIPGL--CAP--GRFRCVCGPGYRPA---GEVCADVDECAVRPPP--CDQLCHN 797
D++EC++ P CA G ++C C GY+ + G C D+DECA+ C C N
Sbjct: 441 DINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 798 TDGSYDCLC-RTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC---SCEDGY 851
GS+ C C +GY L +G NC+D+DEC H C + C N +G + C C + Y
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Query: 852 EK 853
+
Sbjct: 561 RR 562
Score = 75.4 bits (177), Expect = 8e-13
Identities = 47/127 (37%), Positives = 60/127 (47%), Gaps = 22/127 (17%)
Query: 747 DVDECAAIPGLCAP--------GRFRC----VCGPGY-RPAGEVCADVDECAVRPPPCD- 792
D+DEC + C P G FRC C G+ + A C D++EC PC
Sbjct: 262 DIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPI 321
Query: 793 -QLCHNTDGSYDCL-----CRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 844
C NT+GSY C C GY L+E+G C DVDEC C + C N+ GS+
Sbjct: 322 GHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 845 CSCEDGY 851
C C+ GY
Sbjct: 382 CECKTGY 388
Score = 72.1 bits (169), Expect = 8e-12
Identities = 42/101 (41%), Positives = 52/101 (51%), Gaps = 15/101 (14%)
Query: 765 CVCGPGYR--PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCL----CRTGYELDEDG 816
C C GY+ G C DV+EC C + C NT GS+ C C TGYEL ED
Sbjct: 199 CSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN 258
Query: 817 ANCRDVDECERDTHTC--QQICSNTEGSYEC----SCEDGY 851
+ C+D+DECE H C IC NT GS+ C C+ G+
Sbjct: 259 S-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 298
Score = 66.1 bits (154), Expect = 5e-10
Identities = 31/73 (42%), Positives = 40/73 (54%), Gaps = 6/73 (8%)
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 845
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 185 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 846 --SCEDGYEKRGD 856
SC GYE D
Sbjct: 245 DSSCGTGYELTED 257
Score = 58.8 bits (136), Expect = 8e-08
Identities = 49/165 (29%), Positives = 63/165 (38%), Gaps = 20/165 (12%)
Query: 21 YLCCCSVGHAW---GAPCEACPPRGSPAHTALCGEKPGEY---------INPVTNET-KP 67
YLC CSVG G CE S + C G Y ++ V T +
Sbjct: 422 YLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCED 481
Query: 68 IDECDIMP--QLCKPGTCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
IDEC + +C C + P FQC C GY C+D+DEC G C
Sbjct: 482 IDECALPTGGHICS-YRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 540
Query: 125 QCVNLPGAFEC---RCPPGYRLTPSLDECEDVDECGDQRICDHGD 166
C N+ G F C CP YR + + + E D + C D
Sbjct: 541 TCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPND 585
>AK075566-1|BAC11705.1| 638|Homo sapiens protein ( Homo sapiens
cDNA PSEC0266 fis, clone NT2RP3003649, highly similar to
Homo sapiens fibulin-1D mRNA. ).
Length = 638
Score = 215 bits (526), Expect = 4e-55
Identities = 152/444 (34%), Positives = 208/444 (46%), Gaps = 63/444 (14%)
Query: 193 DECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGR-CRN 250
D C P C+ C + +C C G++ + C DVNEC G CR G C N
Sbjct: 113 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 170
Query: 251 TVGSFRCE----CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC---- 302
TVGSFRC+ C GY LT D +C+D+DEC+ H C D C NT G + C
Sbjct: 171 TVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDF--ICQNTLGSFRCRPKL 227
Query: 303 SCGAGW--KLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCE-----CPAGWRFDKTA 354
C +G+ +G C+D +EC + C G C N G Y C+ C G+ ++
Sbjct: 228 QCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEG 286
Query: 355 AVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC 414
CVD E G+ HR C S G+ RC F
Sbjct: 287 TRCVDV-DECAPPAEPCGKGHR----------CVNSPGSF------RCECKTGYYF---- 325
Query: 415 QGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECAL 474
G+ R + D++EC+ P G +C NT GS+ C C G+ L+ DG SC D +EC+
Sbjct: 326 -DGISR--MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 382
Query: 475 DPRICGNGTCSNTRGGYECQCSPGF--TQGPDQTCVDVDECA--EGRASCTFRCHNTAGS 530
P C C+N G Y+C C G+ + TC D+DECA G C++RC N GS
Sbjct: 383 SP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 439
Query: 531 FRCTCP-YGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC---KCPEGYRRTS 584
F+C+CP GY +A +G +C+DIDECV C C N+ G + C +CPE YRR++
Sbjct: 440 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSA 499
Query: 585 A--PQDSENACEDINECEEQEDLC 606
A Q+ + I C + C
Sbjct: 500 ATLQQEKTDTVRCIKSCRPNDVTC 523
Score = 208 bits (509), Expect = 5e-53
Identities = 138/407 (33%), Positives = 185/407 (45%), Gaps = 57/407 (14%)
Query: 111 DECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GDQRICDHGD-CR 168
D C G P C+ QC + C C GY+L CEDV+EC C G+ C
Sbjct: 113 DRCRGGGP-CK--QQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCI 169
Query: 169 NTIGSYRCE----CKPGYTLRE-NVCRDVDECSRPRPVCR-NGTCENLPGAYLCH----C 218
NT+GS+RC+ C GY L E N C+D+DEC C + C+N G++ C C
Sbjct: 170 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 229
Query: 219 DDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCE-----CAPGYTLTADGRNC 272
GF +C+D+NEC C G C NT GS+ C+ C GY L +G C
Sbjct: 230 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 289
Query: 273 RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAG 330
DVDEC PCG+ C N+ G + C C G+ G R CVD +EC+ P G
Sbjct: 290 VDVDECAPPAEPCGKGHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 347
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCS 390
+C N G Y+C C G+R C D +E + C + C +
Sbjct: 348 HKCENTLGSYLCSCSVGFRLSVDGRSCED------INECSSSPCSQE----------CAN 391
Query: 391 EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP--DVCVGGRCVNTDGS 448
++ YC R + + C +D+DEC + +C RC+N GS
Sbjct: 392 VYGSYQCYCRRGYQLSDVDGV-TC----------EDIDECALPTGGHIC-SYRCINIPGS 439
Query: 449 FRCECP-DGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
F+C CP GY LAP+G +C D DEC C N TC N +GG+ C
Sbjct: 440 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 486
Score = 208 bits (507), Expect = 8e-53
Identities = 147/407 (36%), Positives = 199/407 (48%), Gaps = 53/407 (13%)
Query: 234 NECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+ CR GG C+ +CR+T C C GY L +DG +C DV+EC H C R G SC
Sbjct: 113 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC-RLGE-SC 168
Query: 294 TNTNGGYEC----SCGAGWKLV-GRRCVDRDECKELPYVCAGGE-CRNFNGGYVC----E 343
NT G + C SCG G++L C D DEC+ + C C+N G + C +
Sbjct: 169 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 228
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
C +G+ D C+D + L + P + C +EG+ C++
Sbjct: 229 CKSGFIQDALGN-CIDINECLSI----------SAPCPIGHT-CINTEGSYT---CQK-N 272
Query: 404 APDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPD 462
P+ + + G D+DEC + C G RCVN+ GSFRCEC GY D
Sbjct: 273 VPNCGRGYHLNEEG----TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF--D 326
Query: 463 GLS--CVDADECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRA 518
G+S CVD +EC P R+CG+ C NT G Y C CS GF D ++C D++EC+ +
Sbjct: 327 GISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS--S 383
Query: 519 SCTFRCHNTAGSFRCTCPYGYAVA-ADGVHCRDIDECVQEP--RVCPHACENVVGSYICK 575
C+ C N GS++C C GY ++ DGV C DIDEC +C + C N+ GS+ C
Sbjct: 384 PCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCS 443
Query: 576 CP-EGYRRTSAPQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
CP GYR AP C+DI+EC CS C N G F C
Sbjct: 444 CPSSGYR--LAPNGRN--CQDIDECVTGIHNCSINETCFNIQGGFRC 486
Score = 192 bits (469), Expect = 3e-48
Identities = 138/405 (34%), Positives = 175/405 (43%), Gaps = 55/405 (13%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECR- 136
CK C DT C C GY+ + C DV+EC G CR C+N G+F C+
Sbjct: 121 CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 179
Query: 137 ---CPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIGSYRC----ECKPGYTLRE- 186
C GY LT + C+D+DEC G C+NT+GS+RC +CK G+
Sbjct: 180 DSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 238
Query: 187 NVCRDVDECSRPRPVCRNG-TCENLPGAYLC-----HCDDGFKAGPNND-CVDVNECREG 239
C D++EC C G TC N G+Y C +C G+ CVDV+EC
Sbjct: 239 GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPP 298
Query: 240 GMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
C G RC N+ GSFRCEC GY R C DV+EC P GR C NT G
Sbjct: 299 AEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYP---GRLCGHKCENTLG 355
Query: 299 GYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
Y CSC G++L GR C D +EC P C+ EC N G Y C C G++ V
Sbjct: 356 SYLCSCSVGFRLSVDGRSCEDINECSSSP--CS-QECANVYGSYQCYCRRGYQLSDVDGV 412
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
++ E C + C G+ +C P S R+
Sbjct: 413 TCEDIDE----------CALPTGGHICSYRCINIPGSF------QCSCPSSG--YRLAPN 454
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRC---ECPDGY 457
G QD+DEC C + C N G FRC ECP+ Y
Sbjct: 455 GRN----CQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 495
Score = 175 bits (427), Expect = 4e-43
Identities = 127/374 (33%), Positives = 174/374 (46%), Gaps = 52/374 (13%)
Query: 287 RDGNP---SCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGE-CRNFNGGY 340
R G P C +T CSC G++L+ G C D +EC + C GE C N G +
Sbjct: 116 RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 175
Query: 341 VCE----CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWG 396
C+ C G+ + + C D DE E+G + P+ C G
Sbjct: 176 RCQRDSSCGTGYELTEDNS-CKD------IDECESG-------IHNCLPDFICQN--TLG 219
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCE--- 452
+ RC P Q +G D++EC C +G C+NT+GS+ C+
Sbjct: 220 SF--RC-RPKLQCKSGFIQDALGN---CIDINECLSISAPCPIGHTCINTEGSYTCQKNV 273
Query: 453 --CPDGYVLAPDGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFT-QGPDQTCV 508
C GY L +G CVD DECA CG G C N+ G + C+C G+ G + CV
Sbjct: 274 PNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV 333
Query: 509 DVDECAE--GRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
DV+EC GR C +C NT GS+ C+C G+ ++ DG C DI+EC P C C
Sbjct: 334 DVNECQRYPGRL-CGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQECA 390
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED--LCSGGVCINTDGSFLCDC-D 623
NV GSY C C GY+ + + CEDI+EC +CS CIN GSF C C
Sbjct: 391 NVYGSYQCYCRRGYQLSDVDGVT---CEDIDECALPTGGHICSYR-CINIPGSFQCSCPS 446
Query: 624 AGFEPSEDGTDCID 637
+G+ + +G +C D
Sbjct: 447 SGYRLAPNGRNCQD 460
Score = 167 bits (406), Expect = 1e-40
Identities = 95/250 (38%), Positives = 128/250 (51%), Gaps = 22/250 (8%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQC-----GCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
I+EC + C G TC +T + C C GY + C DVDEC+ PC
Sbjct: 244 INECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCG 303
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG--DQRICDHGDCRNTIGSYRCECK 179
+CVN PG+F C C GY C DV+EC R+C H C NT+GSY C C
Sbjct: 304 KGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCS 362
Query: 180 PGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN--DCVDVNE 235
G+ L + C D++ECS P + C N+ G+Y C+C G++ + C D++E
Sbjct: 363 VGFRLSVDGRSCEDINECS-SSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDE 419
Query: 236 CR--EGGMVCRNGRCRNTVGSFRCEC-APGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
C GG +C + RC N GSF+C C + GY L +GRNC+D+DEC H C N +
Sbjct: 420 CALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI--NET 476
Query: 293 CTNTNGGYEC 302
C N GG+ C
Sbjct: 477 CFNIQGGFRC 486
Score = 151 bits (365), Expect = 1e-35
Identities = 91/247 (36%), Positives = 112/247 (45%), Gaps = 26/247 (10%)
Query: 425 QDLDECRVRPDVC-VGGRCVNTDGSFRCE----CPDGYVLAPDGLSCVDADECALDPRIC 479
+D++EC C +G C+NT GSFRC+ C GY L D SC D DEC C
Sbjct: 150 EDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNC 208
Query: 480 -GNGTCSNTRGGYEC----QCSPGFTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFR 532
+ C NT G + C QC GF Q C+D++EC A C C NT GS+
Sbjct: 209 LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYT 268
Query: 533 C-----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSA 585
C C GY + +G C D+DEC C H C N GS+ C+C GY
Sbjct: 269 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 328
Query: 586 PQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYR 645
+ C D+NEC+ G C NT GS+LC C GF S DG C D C
Sbjct: 329 SR----MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED--INECSS 382
Query: 646 SLVSGRC 652
S S C
Sbjct: 383 SPCSQEC 389
Score = 136 bits (328), Expect = 4e-31
Identities = 90/266 (33%), Positives = 122/266 (45%), Gaps = 33/266 (12%)
Query: 416 GGMGRPNLTQDLDECRVRP---DVCVGG-----RCVNTDGSFRCECPDGYVLAPDGLSCV 467
GG+ + +++E + P D C GG +C +T C C GY L DG+SC
Sbjct: 91 GGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCE 150
Query: 468 DADECALDPRICGNG-TCSNTRGGYECQ----CSPGFTQGPDQTCVDVDECAEGRASC-- 520
D +EC C G +C NT G + CQ C G+ D +C D+DEC G +C
Sbjct: 151 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLP 210
Query: 521 TFRCHNTAGSFRC----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC 574
F C NT GSFRC C G+ A G +C DI+EC+ CP H C N GSY C
Sbjct: 211 DFICQNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTC 269
Query: 575 K-----CPEGYRRTSAPQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFEP 628
+ C GY + C D++EC + C G C+N+ GSF C+C G+
Sbjct: 270 QKNVPNCGRGYHL----NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 325
Query: 629 SEDGTDCIDRRTGTCYRSLVSG-RCE 653
C+D Y + G +CE
Sbjct: 326 DGISRMCVDVNECQRYPGRLCGHKCE 351
Score = 97.9 bits (233), Expect = 1e-19
Identities = 52/118 (44%), Positives = 63/118 (53%), Gaps = 15/118 (12%)
Query: 747 DVDECAAIPG-LCAP------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
DV+EC PG LC G + C C G+R + G C D++EC+ PC Q C N
Sbjct: 334 DVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECAN 391
Query: 798 TDGSYDCLCRTGYEL-DEDGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGY 851
GSY C CR GY+L D DG C D+DEC T H C C N GS++CSC GY
Sbjct: 392 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGY 449
Score = 97.5 bits (232), Expect = 2e-19
Identities = 58/176 (32%), Positives = 84/176 (47%), Gaps = 15/176 (8%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C K G Y + ++ ++EC P C +T + C C G+ C D
Sbjct: 317 CECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED 376
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD--ECEDVDECG---DQRICDH 164
++ECS PC +C N+ G+++C C GY+L+ +D CED+DEC IC +
Sbjct: 377 INECS--SSPC--SQECANVYGSYQCYCRRGYQLS-DVDGVTCEDIDECALPTGGHICSY 431
Query: 165 GDCRNTIGSYRCEC-KPGYTLREN--VCRDVDECSRPRPVCR-NGTCENLPGAYLC 216
C N GS++C C GY L N C+D+DEC C N TC N+ G + C
Sbjct: 432 -RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 486
Score = 96.3 bits (229), Expect = 4e-19
Identities = 50/117 (42%), Positives = 61/117 (52%), Gaps = 13/117 (11%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAG--EVCADVDECAVRPPP-CDQLC 795
DVDECA C +PG FRC C GY G +C DV+EC P C C
Sbjct: 291 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 350
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
NT GSY C C G+ L DG +C D++EC + C Q C+N GSY+C C GY+
Sbjct: 351 ENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQ 405
Score = 81.0 bits (191), Expect = 2e-14
Identities = 43/122 (35%), Positives = 63/122 (51%), Gaps = 15/122 (12%)
Query: 747 DVDECAAIPGL--CAP--GRFRCVCGPGYRPA---GEVCADVDECAVRPPP--CDQLCHN 797
D++EC++ P CA G ++C C GY+ + G C D+DECA+ C C N
Sbjct: 376 DINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 435
Query: 798 TDGSYDCLC-RTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC---SCEDGY 851
GS+ C C +GY L +G NC+D+DEC H C + C N +G + C C + Y
Sbjct: 436 IPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 495
Query: 852 EK 853
+
Sbjct: 496 RR 497
Score = 75.4 bits (177), Expect = 8e-13
Identities = 47/127 (37%), Positives = 60/127 (47%), Gaps = 22/127 (17%)
Query: 747 DVDECAAIPGLCAP--------GRFRC----VCGPGY-RPAGEVCADVDECAVRPPPCD- 792
D+DEC + C P G FRC C G+ + A C D++EC PC
Sbjct: 197 DIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPI 256
Query: 793 -QLCHNTDGSYDCL-----CRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 844
C NT+GSY C C GY L+E+G C DVDEC C + C N+ GS+
Sbjct: 257 GHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 316
Query: 845 CSCEDGY 851
C C+ GY
Sbjct: 317 CECKTGY 323
Score = 72.1 bits (169), Expect = 8e-12
Identities = 42/101 (41%), Positives = 52/101 (51%), Gaps = 15/101 (14%)
Query: 765 CVCGPGYR--PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCL----CRTGYELDEDG 816
C C GY+ G C DV+EC C + C NT GS+ C C TGYEL ED
Sbjct: 134 CSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN 193
Query: 817 ANCRDVDECERDTHTC--QQICSNTEGSYEC----SCEDGY 851
+ C+D+DECE H C IC NT GS+ C C+ G+
Sbjct: 194 S-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 233
Score = 66.1 bits (154), Expect = 5e-10
Identities = 31/73 (42%), Positives = 40/73 (54%), Gaps = 6/73 (8%)
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 845
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 120 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 179
Query: 846 --SCEDGYEKRGD 856
SC GYE D
Sbjct: 180 DSSCGTGYELTED 192
Score = 58.8 bits (136), Expect = 8e-08
Identities = 49/165 (29%), Positives = 63/165 (38%), Gaps = 20/165 (12%)
Query: 21 YLCCCSVGHAW---GAPCEACPPRGSPAHTALCGEKPGEY---------INPVTNET-KP 67
YLC CSVG G CE S + C G Y ++ V T +
Sbjct: 357 YLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCED 416
Query: 68 IDECDIMP--QLCKPGTCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
IDEC + +C C + P FQC C GY C+D+DEC G C
Sbjct: 417 IDECALPTGGHICS-YRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 475
Query: 125 QCVNLPGAFEC---RCPPGYRLTPSLDECEDVDECGDQRICDHGD 166
C N+ G F C CP YR + + + E D + C D
Sbjct: 476 TCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPND 520
>X53741-1|CAA37770.1| 566|Homo sapiens fibulin-1 A protein.
Length = 566
Score = 213 bits (519), Expect = 3e-54
Identities = 148/421 (35%), Positives = 202/421 (47%), Gaps = 61/421 (14%)
Query: 193 DECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGR-CRN 250
D C P C+ C + +C C G++ + C DVNEC G CR G C N
Sbjct: 178 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 251 TVGSFRCE----CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC---- 302
TVGSFRC+ C GY LT D +C+D+DEC+ H C D C NT G + C
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDF--ICQNTLGSFRCRPKL 292
Query: 303 SCGAGW--KLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCE-----CPAGWRFDKTA 354
C +G+ +G C+D +EC + C G C N G Y C+ C G+ ++
Sbjct: 293 QCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEG 351
Query: 355 AVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRIC 414
CVD E G+ HR C S G+ RC F
Sbjct: 352 TRCVDV-DECAPPAEPCGKGHR----------CVNSPGSF------RCECKTGYYF---- 390
Query: 415 QGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECAL 474
G+ R + D++EC+ P G +C NT GS+ C C G+ L+ DG SC D +EC+
Sbjct: 391 -DGISR--MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 475 DPRICGNGTCSNTRGGYECQCSPGF--TQGPDQTCVDVDECA--EGRASCTFRCHNTAGS 530
P C C+N G Y+C C G+ + TC D+DECA G C++RC N GS
Sbjct: 448 SP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 504
Query: 531 FRCTCP-YGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC---KCPEGYRRTS 584
F+C+CP GY +A +G +C+DIDECV C C N+ G++ C +CPE YRR++
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENYRRSA 564
Query: 585 A 585
A
Sbjct: 565 A 565
Score = 208 bits (508), Expect = 6e-53
Identities = 147/407 (36%), Positives = 200/407 (49%), Gaps = 53/407 (13%)
Query: 234 NECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+ CR GG C+ +CR+T C C GY L +DG +C DV+EC H C R G SC
Sbjct: 178 DRCRGGGP-CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC-RLGE-SC 233
Query: 294 TNTNGGYEC----SCGAGWKLV-GRRCVDRDECKELPYVCAGGE-CRNFNGGYVC----E 343
NT G + C SCG G++L C D DEC+ + C C+N G + C +
Sbjct: 234 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
C +G+ D C+D + L + P + C +EG+ C++
Sbjct: 294 CKSGFIQDALGN-CIDINECLSI----------SAPCPIGHT-CINTEGSYT---CQK-N 337
Query: 404 APDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPD 462
P+ + + G D+DEC + C G RCVN+ GSFRCEC GY D
Sbjct: 338 VPNCGRGYHLNEEG----TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF--D 391
Query: 463 GLS--CVDADECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRA 518
G+S CVD +EC P R+CG+ C NT G Y C CS GF D ++C D++EC+ +
Sbjct: 392 GISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS--S 448
Query: 519 SCTFRCHNTAGSFRCTCPYGYAVA-ADGVHCRDIDECVQEP--RVCPHACENVVGSYICK 575
C+ C N GS++C C GY ++ DGV C DIDEC +C + C N+ GS+ C
Sbjct: 449 PCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCS 508
Query: 576 CP-EGYRRTSAPQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
CP GYR AP C+DI+EC CS C N G+F C
Sbjct: 509 CPSSGYR--LAPNGRN--CQDIDECVTGIHNCSINETCFNIQGAFRC 551
Score = 206 bits (503), Expect = 3e-52
Identities = 137/407 (33%), Positives = 184/407 (45%), Gaps = 57/407 (14%)
Query: 111 DECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GDQRICDHGD-CR 168
D C G P C+ QC + C C GY+L CEDV+EC C G+ C
Sbjct: 178 DRCRGGGP-CK--QQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCI 234
Query: 169 NTIGSYRCE----CKPGYTLRE-NVCRDVDECSRPRPVCR-NGTCENLPGAYLCH----C 218
NT+GS+RC+ C GY L E N C+D+DEC C + C+N G++ C C
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294
Query: 219 DDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCE-----CAPGYTLTADGRNC 272
GF +C+D+NEC C G C NT GS+ C+ C GY L +G C
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354
Query: 273 RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAG 330
DVDEC PCG+ C N+ G + C C G+ G R CVD +EC+ P G
Sbjct: 355 VDVDECAPPAEPCGKGHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCS 390
+C N G Y+C C G+R C D +E + C + C +
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDGRSCED------INECSSSPCSQE----------CAN 456
Query: 391 EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP--DVCVGGRCVNTDGS 448
++ YC R + + C +D+DEC + +C RC+N GS
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGV-TC----------EDIDECALPTGGHIC-SYRCINIPGS 504
Query: 449 FRCECP-DGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
F+C CP GY LAP+G +C D DEC C N TC N +G + C
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRC 551
Score = 193 bits (470), Expect = 3e-48
Identities = 138/405 (34%), Positives = 176/405 (43%), Gaps = 55/405 (13%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECR- 136
CK C DT C C GY+ + C DV+EC G CR C+N G+F C+
Sbjct: 186 CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 137 ---CPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIGSYRC----ECKPGYTLRE- 186
C GY LT + C+D+DEC G C+NT+GS+RC +CK G+
Sbjct: 245 DSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 187 NVCRDVDECSRPRPVCRNG-TCENLPGAYLC-----HCDDGFKAGPNND-CVDVNECREG 239
C D++EC C G TC N G+Y C +C G+ CVDV+EC
Sbjct: 304 GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPP 363
Query: 240 GMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG 298
C G RC N+ GSFRCEC GY R C DV+EC P GR C NT G
Sbjct: 364 AEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYP---GRLCGHKCENTLG 420
Query: 299 GYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
Y CSC G++L GR C D +EC P C+ EC N G Y C C G++ V
Sbjct: 421 SYLCSCSVGFRLSVDGRSCEDINECSSSP--CS-QECANVYGSYQCYCRRGYQLSDVDGV 477
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
++ E C + C G+ +C P S R+
Sbjct: 478 TCEDIDE----------CALPTGGHICSYRCINIPGSF------QCSCPSSG--YRLAPN 519
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRC---ECPDGY 457
G QD+DEC C + C N G+FRC ECP+ Y
Sbjct: 520 GRN----CQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENY 560
Score = 175 bits (427), Expect = 4e-43
Identities = 127/374 (33%), Positives = 174/374 (46%), Gaps = 52/374 (13%)
Query: 287 RDGNP---SCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGE-CRNFNGGY 340
R G P C +T CSC G++L+ G C D +EC + C GE C N G +
Sbjct: 181 RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 240
Query: 341 VCE----CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWG 396
C+ C G+ + + C D DE E+G + P+ C G
Sbjct: 241 RCQRDSSCGTGYELTEDNS-CKD------IDECESG-------IHNCLPDFICQN--TLG 284
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCE--- 452
+ RC P Q +G D++EC C +G C+NT+GS+ C+
Sbjct: 285 SF--RC-RPKLQCKSGFIQDALGN---CIDINECLSISAPCPIGHTCINTEGSYTCQKNV 338
Query: 453 --CPDGYVLAPDGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFT-QGPDQTCV 508
C GY L +G CVD DECA CG G C N+ G + C+C G+ G + CV
Sbjct: 339 PNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV 398
Query: 509 DVDECAE--GRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
DV+EC GR C +C NT GS+ C+C G+ ++ DG C DI+EC P C C
Sbjct: 399 DVNECQRYPGRL-CGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQECA 455
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED--LCSGGVCINTDGSFLCDC-D 623
NV GSY C C GY+ + + CEDI+EC +CS CIN GSF C C
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVT---CEDIDECALPTGGHICSYR-CINIPGSFQCSCPS 511
Query: 624 AGFEPSEDGTDCID 637
+G+ + +G +C D
Sbjct: 512 SGYRLAPNGRNCQD 525
Score = 165 bits (400), Expect = 8e-40
Identities = 94/250 (37%), Positives = 127/250 (50%), Gaps = 22/250 (8%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQC-----GCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
I+EC + C G TC +T + C C GY + C DVDEC+ PC
Sbjct: 309 INECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCG 368
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG--DQRICDHGDCRNTIGSYRCECK 179
+CVN PG+F C C GY C DV+EC R+C H C NT+GSY C C
Sbjct: 369 KGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCS 427
Query: 180 PGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN--DCVDVNE 235
G+ L + C D++ECS P + C N+ G+Y C+C G++ + C D++E
Sbjct: 428 VGFRLSVDGRSCEDINECS-SSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDE 484
Query: 236 CR--EGGMVCRNGRCRNTVGSFRCEC-APGYTLTADGRNCRDVDECDELPHPCGRDGNPS 292
C GG +C + RC N GSF+C C + GY L +GRNC+D+DEC H C N +
Sbjct: 485 CALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI--NET 541
Query: 293 CTNTNGGYEC 302
C N G + C
Sbjct: 542 CFNIQGAFRC 551
Score = 151 bits (365), Expect = 1e-35
Identities = 91/247 (36%), Positives = 112/247 (45%), Gaps = 26/247 (10%)
Query: 425 QDLDECRVRPDVC-VGGRCVNTDGSFRCE----CPDGYVLAPDGLSCVDADECALDPRIC 479
+D++EC C +G C+NT GSFRC+ C GY L D SC D DEC C
Sbjct: 215 EDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNC 273
Query: 480 -GNGTCSNTRGGYEC----QCSPGFTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFR 532
+ C NT G + C QC GF Q C+D++EC A C C NT GS+
Sbjct: 274 LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 533 C-----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSA 585
C C GY + +G C D+DEC C H C N GS+ C+C GY
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 586 PQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYR 645
+ C D+NEC+ G C NT GS+LC C GF S DG C D C
Sbjct: 394 SR----MCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED--INECSS 447
Query: 646 SLVSGRC 652
S S C
Sbjct: 448 SPCSQEC 454
Score = 136 bits (328), Expect = 4e-31
Identities = 90/266 (33%), Positives = 122/266 (45%), Gaps = 33/266 (12%)
Query: 416 GGMGRPNLTQDLDECRVRP---DVCVGG-----RCVNTDGSFRCECPDGYVLAPDGLSCV 467
GG+ + +++E + P D C GG +C +T C C GY L DG+SC
Sbjct: 156 GGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCE 215
Query: 468 DADECALDPRICGNG-TCSNTRGGYECQ----CSPGFTQGPDQTCVDVDECAEGRASC-- 520
D +EC C G +C NT G + CQ C G+ D +C D+DEC G +C
Sbjct: 216 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLP 275
Query: 521 TFRCHNTAGSFRC----TCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYIC 574
F C NT GSFRC C G+ A G +C DI+EC+ CP H C N GSY C
Sbjct: 276 DFICQNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTC 334
Query: 575 K-----CPEGYRRTSAPQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFEP 628
+ C GY + C D++EC + C G C+N+ GSF C+C G+
Sbjct: 335 QKNVPNCGRGYHL----NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 629 SEDGTDCIDRRTGTCYRSLVSG-RCE 653
C+D Y + G +CE
Sbjct: 391 DGISRMCVDVNECQRYPGRLCGHKCE 416
Score = 99.1 bits (236), Expect = 6e-20
Identities = 59/176 (33%), Positives = 85/176 (48%), Gaps = 15/176 (8%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD 109
C K G Y + ++ ++EC P C +T + C C G+ C D
Sbjct: 382 CECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED 441
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD--ECEDVDECG---DQRICDH 164
++ECS PC +C N+ G+++C C GY+L+ +D CED+DEC IC +
Sbjct: 442 INECS--SSPC--SQECANVYGSYQCYCRRGYQLS-DVDGVTCEDIDECALPTGGHICSY 496
Query: 165 GDCRNTIGSYRCEC-KPGYTLREN--VCRDVDECSRPRPVCR-NGTCENLPGAYLC 216
C N GS++C C GY L N C+D+DEC C N TC N+ GA+ C
Sbjct: 497 -RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRC 551
Score = 97.9 bits (233), Expect = 1e-19
Identities = 52/118 (44%), Positives = 63/118 (53%), Gaps = 15/118 (12%)
Query: 747 DVDECAAIPG-LCAP------GRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
DV+EC PG LC G + C C G+R + G C D++EC+ PC Q C N
Sbjct: 399 DVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECAN 456
Query: 798 TDGSYDCLCRTGYEL-DEDGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGY 851
GSY C CR GY+L D DG C D+DEC T H C C N GS++CSC GY
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGY 514
Score = 96.3 bits (229), Expect = 4e-19
Identities = 50/117 (42%), Positives = 61/117 (52%), Gaps = 13/117 (11%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGYRPAG--EVCADVDECAVRPPP-CDQLC 795
DVDECA C +PG FRC C GY G +C DV+EC P C C
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 415
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
NT GSY C C G+ L DG +C D++EC + C Q C+N GSY+C C GY+
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQ 470
Score = 81.4 bits (192), Expect = 1e-14
Identities = 43/122 (35%), Positives = 64/122 (52%), Gaps = 15/122 (12%)
Query: 747 DVDECAAIPGL--CAP--GRFRCVCGPGYRPA---GEVCADVDECAVRPPP--CDQLCHN 797
D++EC++ P CA G ++C C GY+ + G C D+DECA+ C C N
Sbjct: 441 DINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 798 TDGSYDCLC-RTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC---SCEDGY 851
GS+ C C +GY L +G NC+D+DEC H C + C N +G++ C C + Y
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENY 560
Query: 852 EK 853
+
Sbjct: 561 RR 562
Score = 75.4 bits (177), Expect = 8e-13
Identities = 47/127 (37%), Positives = 60/127 (47%), Gaps = 22/127 (17%)
Query: 747 DVDECAAIPGLCAP--------GRFRC----VCGPGY-RPAGEVCADVDECAVRPPPCD- 792
D+DEC + C P G FRC C G+ + A C D++EC PC
Sbjct: 262 DIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPI 321
Query: 793 -QLCHNTDGSYDCL-----CRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 844
C NT+GSY C C GY L+E+G C DVDEC C + C N+ GS+
Sbjct: 322 GHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 845 CSCEDGY 851
C C+ GY
Sbjct: 382 CECKTGY 388
Score = 72.1 bits (169), Expect = 8e-12
Identities = 42/101 (41%), Positives = 52/101 (51%), Gaps = 15/101 (14%)
Query: 765 CVCGPGYR--PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCL----CRTGYELDEDG 816
C C GY+ G C DV+EC C + C NT GS+ C C TGYEL ED
Sbjct: 199 CSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN 258
Query: 817 ANCRDVDECERDTHTC--QQICSNTEGSYEC----SCEDGY 851
+ C+D+DECE H C IC NT GS+ C C+ G+
Sbjct: 259 S-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 298
Score = 66.1 bits (154), Expect = 5e-10
Identities = 31/73 (42%), Positives = 40/73 (54%), Gaps = 6/73 (8%)
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 845
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 185 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 846 --SCEDGYEKRGD 856
SC GYE D
Sbjct: 245 DSSCGTGYELTED 257
Score = 58.8 bits (136), Expect = 8e-08
Identities = 46/141 (32%), Positives = 56/141 (39%), Gaps = 20/141 (14%)
Query: 21 YLCCCSVGHAW---GAPCEACPPRGSPAHTALCGEKPGEY---------INPVTNET-KP 67
YLC CSVG G CE S + C G Y ++ V T +
Sbjct: 422 YLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCED 481
Query: 68 IDECDIMP--QLCKPGTCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
IDEC + +C C + P FQC C GY C+D+DEC G C
Sbjct: 482 IDECALPTGGHICS-YRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 540
Query: 125 QCVNLPGAFEC---RCPPGYR 142
C N+ GAF C CP YR
Sbjct: 541 TCFNIQGAFRCLAFECPENYR 561
>BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein.
Length = 647
Score = 210 bits (514), Expect = 1e-53
Identities = 186/588 (31%), Positives = 257/588 (43%), Gaps = 100/588 (17%)
Query: 64 ETKPIDECDIMPQLC-KPGTCHDTPTGF-QCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
+ K D C P C K G CH +G QC C G+ T C+ D CS PC
Sbjct: 115 QAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGW----TGEQCQLRDFCSAN--PCV 166
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDEC-GDQRICDHG-DCRNTIGSYRCEC 178
C+ +C CPPG+ CE DV+EC D C G C NT+GS++C C
Sbjct: 167 NGGVCLATYPQIQCHCPPGFEG----HACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Query: 179 KPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGA----YLCHCDDGFKAGPNNDCVDVN 234
G R C PR GTC+ +P +LC C GF GP DC +VN
Sbjct: 223 PVGQEGPRCELR-AGPCP-PRGCSNGGTCQLMPEKDSTFHLCLCPPGF-IGP--DC-EVN 276
Query: 235 ECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPS 292
C+NG C++ + ++ C C +T G +C DVDEC+ P R+G +
Sbjct: 277 PDNCVSHQCQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQGPPHCRNGG-T 331
Query: 293 CTNTNGGYECSCGAGWKLVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCECPAGWRF 350
C N+ G + C C +GW G C + D+C + CA G C + G + C CP G
Sbjct: 332 CQNSAGSFHCVCVSGWG--GTSCEENLDDC--IAATCAPGSTCIDRVGSFSCLCPPG--- 384
Query: 351 DKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
+T +C +++C + CH + CS P +
Sbjct: 385 -RTGLLC--HLEDMCLSQ----PCHG---------DAQCSTN------------PLTGST 416
Query: 411 MRICQGGMGRPNLTQDLDECRVR---PDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC 466
+ +CQ G P QDLDEC + P C GG C+NT GSF C CP GY G C
Sbjct: 417 LCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT----GSRC 472
Query: 467 -VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRASCTFRC 524
D +EC P G+ TC + + C C PG +G Q C V+ +ECA C
Sbjct: 473 EADHNECLSQPCHPGS-TCLDLLATFHCLCPPGL-EG--QLCEVETNECASAPCLNHADC 528
Query: 525 HNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVCPHACENVVGSYICKCPEGYRRT 583
H+ F+C C G++ G C DIDEC P C++ G++ CKC G+
Sbjct: 529 HDLLNGFQCICLPGFS----GTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGF--- 581
Query: 584 SAPQDSENACEDINECEEQEDLCS-GGVCINTDGSFLCDCDAGFEPSE 630
+ +++EC D C G C++ G+F C C +GF S+
Sbjct: 582 ----EGPRCQTEVDEC--LSDPCPVGASCLDLPGAFFCLCPSGFTGSQ 623
Score = 163 bits (397), Expect = 2e-39
Identities = 163/586 (27%), Positives = 241/586 (41%), Gaps = 93/586 (15%)
Query: 21 YLCCCSVGHAWGAPCEA-----CPP----RGSPAHTALCGEKPGEYINPVTNETKPI-DE 70
+LC C G G C+A CPP + H G + T E + D
Sbjct: 101 FLCTCLPGFT-GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDF 159
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNL 129
C P + G C T QC C G+E H C RDV+EC PC C N
Sbjct: 160 CSANPCV-NGGVCLATYPQIQCHCPPGFE----GHACERDVNECFQDPGPCPKGTSCHNT 214
Query: 130 PGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCR----NTIGSYRCECKPGYTL 184
G+F+C CP G P CE C + + G C+ + C C PG+ +
Sbjct: 215 LGSFQCLCPVGQE-GP---RCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGF-I 269
Query: 185 RENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCV-DVNECR-EGGM 241
+ + D C + C+NG TC++ Y C C + + DC DV+EC +G
Sbjct: 270 GPDCEVNPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGW---DCSEDVDECETQGPP 324
Query: 242 VCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGG 299
CRNG C+N+ GSF C C G+ G +C + +D+C + C +C + G
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDC--IAATCA--PGSTCIDRVGS 376
Query: 300 YECSCGAGWKLVGRRCVDRDECKELPYVCAG-GECRN--FNGGYVCECPAGWRFDKTAAV 356
+ C C G G C D C P C G +C G +C C G+ +
Sbjct: 377 FSCLCPPG--RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTLCLCQPGY----SGPT 428
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
C + E C A+ Q P C G + C P F +C
Sbjct: 429 CHQDLDE----------CLMAQ--QGPSP---CEHGGS----CLNTP----GSFNCLCPP 465
Query: 417 GMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALD 475
G D +EC +P G C++ +F C CP G +G C V+ +ECA
Sbjct: 466 GYTGSRCEADHNECLSQP-CHPGSTCLDLLATFHCLCPPGL----EGQLCEVETNECASA 520
Query: 476 PRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
P + + C + G++C C PGF+ + D+DEC + +C + G+F C C
Sbjct: 521 PCL-NHADCHDLLNGFQCICLPGFSGTRCEE--DIDECRSSPCANGGQCQDQPGAFHCKC 577
Query: 536 PYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGY 580
G+ +G C+ ++DEC+ +P +C ++ G++ C CP G+
Sbjct: 578 LPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGF 619
Score = 145 bits (351), Expect = 7e-34
Identities = 153/527 (29%), Positives = 211/527 (40%), Gaps = 105/527 (19%)
Query: 165 GDCRN-TIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCE-------NLPGA-- 213
G C + ++G C+C PG+ L E C+ D C + +C+NG +C+ LP +
Sbjct: 39 GTCLSLSLGQGTCQCAPGF-LGET-CQFPDPCQNAQ-LCQNGGSCQALLPAPLGLPSSPS 95
Query: 214 -----YLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCR-NTVGSFRCECAPGYTLTA 267
+LC C GF G + C + GRC G +C C PG+T
Sbjct: 96 PLTPSFLCTCLPGF-TGERCQAKLEDPCPPS-FCSKRGRCHIQASGRPQCSCMPGWT--- 150
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV-DRDECKELPY 326
G C+ D C +PC G C T +C C G++ G C D +EC + P
Sbjct: 151 -GEQCQLRDFCSA--NPCVNGG--VCLATYPQIQCHCPPGFE--GHACERDVNECFQDPG 203
Query: 327 VCAGG-ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARP 385
C G C N G + C CP G + C E AG C P
Sbjct: 204 PCPKGTSCHNTLGSFQCLCPVG------------QEGPRC--ELRAGPC----------P 239
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN- 444
CS G C+ P DS + +C G P +C V PD CV +C N
Sbjct: 240 PRGCSNGGT----CQLMPEKDSTFHLCLCPPGFIGP-------DCEVNPDNCVSHQCQNG 288
Query: 445 ---TDG--SFRCECPDGYVLAPDGLSCV-DADECALD-PRICGNG-TCSNTRGGYECQCS 496
DG ++ C CP+ + G C D DEC P C NG TC N+ G + C C
Sbjct: 289 GTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
Query: 497 PGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
G+ G ++D+C + C + GSF C CP G G+ C D C+
Sbjct: 345 SGW--GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMCLS 398
Query: 557 EPRVCPHACEN--VVGSYICKCPEGYRRTSAPQDSEN---ACEDINECEEQEDLCSGGVC 611
+P C + GS +C C GY + QD + A + + CE GG C
Sbjct: 399 QPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH------GGSC 452
Query: 612 INTDGSFLCDCDAGFEPSE---DGTDCIDRRT---GTCYRSLVSGRC 652
+NT GSF C C G+ S D +C+ + TC L + C
Sbjct: 453 LNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 499
Score = 116 bits (280), Expect = 3e-25
Identities = 85/251 (33%), Positives = 119/251 (47%), Gaps = 29/251 (11%)
Query: 33 APCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKP----GTCHDTPT 88
A C P GS LC +PG Y P ++ +DEC + Q P G+C +TP
Sbjct: 405 AQCSTNPLTGS----TLCLCQPG-YSGPTCHQD--LDECLMAQQGPSPCEHGGSCLNTPG 457
Query: 89 GFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
F C C GY T C D +EC PC + C++L F C CPPG L L
Sbjct: 458 SFNCLCPPGY----TGSRCEADHNECL--SQPCHPGSTCLDLLATFHCLCPPG--LEGQL 509
Query: 148 DECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTC 207
E E +EC +H DC + + ++C C PG++ D+DEC R P G C
Sbjct: 510 CEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS-GTRCEEDIDEC-RSSPCANGGQC 566
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTLT 266
++ PGA+ C C GF+ GP +V+EC C G C + G+F C C G+T
Sbjct: 567 QDQPGAFHCKCLPGFE-GPRCQ-TEVDECLSD--PCPVGASCLDLPGAFFCLCPSGFT-G 621
Query: 267 ADGRNCRDVDE 277
+ GR+ +++ E
Sbjct: 622 SQGRHWKELAE 632
Score = 96.7 bits (230), Expect = 3e-19
Identities = 119/412 (28%), Positives = 163/412 (39%), Gaps = 91/412 (22%)
Query: 243 CRNG-RCRN-TVGSFRCECAPGYTLTADGRNCRDVDECDE-------------LPHPCGR 287
C NG C + ++G C+CAPG+ G C+ D C LP P G
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFL----GETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 90
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECR-NFNGGYVCECP 345
+PS + + C+C G+ G RC + E P C+ G C +G C C
Sbjct: 91 PSSPSPLTPS--FLCTCLPGF--TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCE-RCPA 404
GW T C + ++ C A P C + G Y + +C
Sbjct: 147 PGW----TGEQC--QLRDFC----------SANP--------CVNGGVCLATYPQIQCHC 182
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDG 463
P E C+ +D++EC P C G C NT GSF+C CP G +G
Sbjct: 183 PPGFE-GHACE---------RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEG 228
Query: 464 LSC-VDADECALDPRICGN-GTC----SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGR 517
C + A C PR C N GTC + C C PGF GPD V+ D C +
Sbjct: 229 PRCELRAGPC--PPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI-GPDCE-VNPDNCVSHQ 284
Query: 518 ASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDEC-VQEPRVCPH--ACENVVGSYI 573
C + ++ C CP + G C D+DEC Q P C + C+N GS+
Sbjct: 285 CQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
C C G+ TS E++++C G CI+ GSF C C G
Sbjct: 341 CVCVSGWGGTSCE-------ENLDDC-IAATCAPGSTCIDRVGSFSCLCPPG 384
Score = 94.3 bits (224), Expect = 2e-18
Identities = 130/513 (25%), Positives = 177/513 (34%), Gaps = 80/513 (15%)
Query: 380 LQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG 439
L L + C C+ G E C PD + ++CQ G L P
Sbjct: 44 LSLGQGTCQCAPGFLG----ETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 99
Query: 440 GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGN-GTCS-NTRGGYECQCSP 497
SF C C G+ G C E P C G C G +C C P
Sbjct: 100 --------SFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMP 147
Query: 498 GFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQ 556
G+T + C D C+ C T +C CP G+ +G C RD++EC Q
Sbjct: 148 GWT---GEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQ 200
Query: 557 EPRVCPH--ACENVVGSYICKCP---EGYR-RTSAPQDSENACEDINECEEQEDLCSG-G 609
+P CP +C N +GS+ C CP EG R A C + C+ + S
Sbjct: 201 DPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFH 260
Query: 610 VCINTDGSFLCDCDAGFE-----PSEDGTDC---IDRRTGTCYRSLVSGRCEPEXXXXXX 661
+C+ G DC+ + ++G C +D T C + C +
Sbjct: 261 LCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECET 320
Query: 662 XXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWG-SECELCPAPGSPARLDLCTAVNLTPX 720
G C C G WG + CE LD C A P
Sbjct: 321 QGPPHCRNGGTCQNSAGSF---HCVCVSG--WGGTSCE--------ENLDDCIAATCAPG 367
Query: 721 XXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP----GLCAP----GRFRCVCGPGYR 772
L D+ C + P C+ G C+C PGY
Sbjct: 368 STCIDRVGSFSCLCPPGRTGLLCHLEDM--CLSQPCHGDAQCSTNPLTGSTLCLCQPGY- 424
Query: 773 PAGEVC-ADVDECAVR---PPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR-DVDEC 825
+G C D+DEC + P PC+ C NT GS++CLC GY G+ C D +EC
Sbjct: 425 -SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNEC 479
Query: 826 ERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
C + ++ C C G E G C
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLE--GQLC 510
Score = 71.7 bits (168), Expect = 1e-11
Identities = 108/408 (26%), Positives = 142/408 (34%), Gaps = 80/408 (19%)
Query: 472 CALDPRICGNG-TC-SNTRGGYECQCSPGF----TQGPDQTCVDVDECAEGRASCTFRCH 525
C P C NG TC S + G CQC+PGF Q PD C + C G SC
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNG-GSCQALLP 85
Query: 526 NTAG----------SFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH--ACE-NVVGSY 572
G SF CTC G+ G C+ E P C C G
Sbjct: 86 APLGLPSSPSPLTPSFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRP 141
Query: 573 ICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDG 632
C C G+ T + C N C +GGVC+ T C C GFE G
Sbjct: 142 QCSCMPGW--TGEQCQLRDFC-SANPC------VNGGVCLATYPQIQCHCPPGFE----G 188
Query: 633 TDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAA 692
C +R C++ G C P+ +A C G +
Sbjct: 189 HAC-ERDVNECFQD--PGPC-PKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCS 244
Query: 693 WGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECA 752
G C+L P S L LC + P D + D C
Sbjct: 245 NGGTCQLMPEKDSTFHLCLCPPGFIGP-----------------------DCEVNPDNCV 281
Query: 753 AIP----GLCAPG--RFRCVCGPGYRPAGEVCADVDECAVR-PPPCDQ--LCHNTDGSYD 803
+ G C G + C+C P + DVDEC + PP C C N+ GS+
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLC-PETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340
Query: 804 CLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDG 850
C+C +G+ G +C + +D+C T C + GS+ C C G
Sbjct: 341 CVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG 384
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 18/117 (15%)
Query: 746 ADVDECAAIPGLCAPGR--------FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCH 796
AD +EC + P C PG F C+C PG G++C + +ECA P CH
Sbjct: 474 ADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE--GQLCEVETNECASAPCLNHADCH 529
Query: 797 NTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+ + C+C G+ G C D+DEC C + G++ C C G+E
Sbjct: 530 DLLNGFQCICLPGFS----GTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE 582
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/113 (31%), Positives = 54/113 (47%), Gaps = 14/113 (12%)
Query: 747 DVDECAAIPGL----CAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+ +ECA+ P L C F+C+C PG+ +G C D+DEC P C +
Sbjct: 513 ETNECASAPCLNHADCHDLLNGFQCICLPGF--SGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G++ C C G+E G C+ +VDEC D C + G++ C C G+
Sbjct: 571 GAFHCKCLPGFE----GPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGF 619
Score = 48.4 bits (110), Expect = 1e-04
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 8/97 (8%)
Query: 757 LCAPGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 815
L PG F C+C PGY G C AD +EC +P C + ++ CLC G E
Sbjct: 453 LNTPGSFNCLCPPGY--TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE---- 506
Query: 816 GANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C + +EC C + ++C C G+
Sbjct: 507 GQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 543
>AK027344-1|BAB55049.1| 741|Homo sapiens protein ( Homo sapiens
cDNA FLJ14438 fis, clone HEMBB1000317, weakly similar to
FIBULIN-1, ISOFORM D PRECURSOR. ).
Length = 741
Score = 208 bits (508), Expect = 6e-53
Identities = 107/289 (37%), Positives = 145/289 (50%), Gaps = 20/289 (6%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC--RCPP 139
+CH+ + C C G C+D+DEC+ GR C C N G++ C RC
Sbjct: 343 SCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGS 402
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPR 199
G+R T C+D++EC + C H C N IGS+ C C+PGY L+ C DV+EC +
Sbjct: 403 GFRRTSDGLSCQDINECQESSPC-HQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQN- 460
Query: 200 PVCR-NGTCENLPGAYLCH--CDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSF 255
VCR + C+N G Y C C +G N C+D++EC++G CR N C NT GS+
Sbjct: 461 -VCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSY 519
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GR 313
RC C GY GR C D+DEC+ C + C NT G Y+C C G++L G+
Sbjct: 520 RCVCPRGYRSQGVGRPCMDIDECENTD-ACQHE----CKNTFGSYQCICPPGYQLTHNGK 574
Query: 314 RCVDRDECKELPYVCAGGE-CRNFNGGYVC---ECPAGWRFDKTAAVCV 358
C D DEC E C C N G Y C CP ++ D + C+
Sbjct: 575 TCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCL 623
Score = 184 bits (448), Expect = 1e-45
Identities = 102/276 (36%), Positives = 136/276 (49%), Gaps = 22/276 (7%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C G+ D+ C D DEC+ G P C C N G + C CP G + C+D+
Sbjct: 315 CPSGFTLDSVGPFCADEDECAAGNP-CSH--SCHNAMGTYYCSCPKGLTIAADGRTCQDI 371
Query: 154 DECG-DQRICDHG-DCRNTIGSYRCECKPGYTLRENV----CRDVDECSRPRPVCRNGTC 207
DEC + C G DC NTIGSYRC + G R C+D++EC P C C
Sbjct: 372 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RC 429
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRC-ECAPGYTL 265
N G++ C C+ G++ C+DVNECR+ VCR + C+NT G ++C + P
Sbjct: 430 FNAIGSFHCGCEPGYQL-KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNGMT 486
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKE 323
A+ C D+DEC + H C N C NT G Y C C G++ VGR C+D DEC+
Sbjct: 487 KAENGTCIDIDECKDGTHQCRY--NQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECEN 544
Query: 324 LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD 359
C EC+N G Y C CP G++ C D
Sbjct: 545 TD-ACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQD 578
Score = 180 bits (437), Expect = 3e-44
Identities = 119/328 (36%), Positives = 149/328 (45%), Gaps = 45/328 (13%)
Query: 301 ECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
+C G VG C D DEC C+ C N G Y C CP G C D
Sbjct: 314 QCPSGFTLDSVGPFCADEDECAA-GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQD- 370
Query: 361 RKELCYDEWEAGR--CHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
DE GR CH A +C + G+ RC + F R G
Sbjct: 371 -----IDECALGRHTCH-------AGQDCDNTIGSY------RCVVRCGSGFRRTSDGLS 412
Query: 419 GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRI 478
QD++EC+ C RC N GSF C C GY L G C+D +EC + +
Sbjct: 413 -----CQDINECQ-ESSPC-HQRCFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQN--V 461
Query: 479 CG-NGTCSNTRGGYEC--QCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFRC 533
C + C NTRGGY+C C G T+ + TC+D+DEC +G C + C NT GS+RC
Sbjct: 462 CRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRC 521
Query: 534 TCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENAC 593
CP GY G C DIDEC + C H C+N GSY C CP GY+ T + C
Sbjct: 522 VCPRGYRSQGVGRPCMDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLT----HNGKTC 576
Query: 594 EDINECEEQEDLCS-GGVCINTDGSFLC 620
+DI+EC EQ C +C N GS+ C
Sbjct: 577 QDIDECLEQNVHCGPNRMCFNMRGSYQC 604
Score = 174 bits (423), Expect = 1e-42
Identities = 103/281 (36%), Positives = 140/281 (49%), Gaps = 23/281 (8%)
Query: 35 CEACPPRGSPAHTAL----CGEKPGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTG 89
C A P H A+ C G I + IDEC + C G C +T
Sbjct: 334 CAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGS 393
Query: 90 FQC--GCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
++C C G+ + C+D++EC P C +C N G+F C C PGY+L
Sbjct: 394 YRCVVRCGSGFRRTSDGLSCQDINECQESSP-CH--QRCFNAIGSFHCGCEPGYQLKGR- 449
Query: 148 DECEDVDECGDQRICDHGD-CRNTIGSYRCE--CKPGYTLREN-VCRDVDECSRPRPVCR 203
+C DV+EC Q +C C+NT G Y+C C G T EN C D+DEC CR
Sbjct: 450 -KCMDVNECR-QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCR 507
Query: 204 -NGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAP 261
N CEN G+Y C C G+++ G C+D++EC E C++ C+NT GS++C C P
Sbjct: 508 YNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDEC-ENTDACQH-ECKNTFGSYQCICPP 565
Query: 262 GYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC 302
GY LT +G+ C+D+DEC E CG N C N G Y+C
Sbjct: 566 GYQLTHNGKTCQDIDECLEQNVHCG--PNRMCFNMRGSYQC 604
Score = 172 bits (419), Expect = 4e-42
Identities = 121/341 (35%), Positives = 161/341 (47%), Gaps = 55/341 (16%)
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRC 315
+C G+TL + G C D DEC +PC SC N G Y CSC G + GR C
Sbjct: 314 QCPSGFTLDSVGPFCADEDEC-AAGNPCSH----SCHNAMGTYYCSCPKGLTIAADGRTC 368
Query: 316 VDRDECKELPYVC-AGGECRNFNGGYVC--ECPAGWRFDKTAAVCVDERKELCYDEWEAG 372
D DEC + C AG +C N G Y C C +G+R C D + C E+
Sbjct: 369 QDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINE--CQ---ESS 423
Query: 373 RCHRARPLQLARPECCCSEGAAW-GRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECR 431
CH+ + C C G GR C D++ECR
Sbjct: 424 PCHQRCFNAIGSFHCGCEPGYQLKGRKC-------------------------MDVNECR 458
Query: 432 VRPDVCVGGR-CVNTDGSFRCE--CPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNT 487
+VC + C NT G ++C CP+G A +G +C+D DEC C N C NT
Sbjct: 459 --QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG-TCIDIDECKDGTHQCRYNQICENT 515
Query: 488 RGGYECQCSPGF-TQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGV 546
RG Y C C G+ +QG + C+D+DEC E +C C NT GS++C CP GY + +G
Sbjct: 516 RGSYRCVCPRGYRSQGVGRPCMDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLTHNGK 574
Query: 547 HCRDIDECVQEPRVC-PH-ACENVVGSYIC---KCPEGYRR 582
C+DIDEC+++ C P+ C N+ GSY C CP Y+R
Sbjct: 575 TCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 615
Score = 171 bits (415), Expect = 1e-41
Identities = 126/360 (35%), Positives = 162/360 (45%), Gaps = 55/360 (15%)
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVD 193
+CP G+ L C D DEC C H C N +G+Y C C G T+ + C+D+D
Sbjct: 314 QCPSGFTLDSVGPFCADEDECAAGNPCSH-SCHNAMGTYYCSCPKGLTIAADGRTCQDID 372
Query: 194 ECSRPRPVCRNG-TCENLPGAYLC--HCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCR 249
EC+ R C G C+N G+Y C C GF+ + C D+NEC+E C RC
Sbjct: 373 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESS-PCHQ-RCF 430
Query: 250 NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC--SCGAG 307
N +GSF C C PGY L GR C DV+EC + + C D + C NT GGY+C C G
Sbjct: 431 NAIGSFHCGCEPGYQL--KGRKCMDVNECRQ--NVCRPDQH--CKNTRGGYKCIDLCPNG 484
Query: 308 W-KLVGRRCVDRDECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
K C+D DECK+ + C + C N G Y C CP G+R C+D
Sbjct: 485 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMD------ 538
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
DE C Q EC +G Y +C P ++ G Q
Sbjct: 539 IDE-----CENTDACQ---HEC----KNTFGSY--QCICPPG---YQLTHNG----KTCQ 577
Query: 426 DLDECRVRPDVCVGGR-CVNTDGSFRC---ECPDGYVLAP-DGL---SCVDAD-ECALDP 476
D+DEC + C R C N GS++C CP Y P G +C D ECAL P
Sbjct: 578 DIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLECALSP 637
Score = 153 bits (371), Expect = 3e-36
Identities = 107/302 (35%), Positives = 136/302 (45%), Gaps = 44/302 (14%)
Query: 343 ECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERC 402
+CP+G+ D C DE DE AG C S A G Y C
Sbjct: 314 QCPSGFTLDSVGPFCADE------DECAAGN------------PCSHSCHNAMGTYYCSC 355
Query: 403 PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRC--ECPDGYVL 459
P + + I G QD+DEC + C G+ C NT GS+RC C G+
Sbjct: 356 P-----KGLTIAADG----RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRR 406
Query: 460 APDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS 519
DGLSC D +EC + C + C N G + C C PG+ Q + C+DV+EC +
Sbjct: 407 TSDGLSCQDINECQ-ESSPC-HQRCFNAIGSFHCGCEPGY-QLKGRKCMDVNECRQNVCR 463
Query: 520 CTFRCHNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPH--ACENVVGSYICK 575
C NT G ++C CP G A +G C DIDEC C + CEN GSY C
Sbjct: 464 PDQHCKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCV 522
Query: 576 CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
CP GYR Q C DI+ECE D C C NT GS+ C C G++ + +G C
Sbjct: 523 CPRGYRS----QGVGRPCMDIDECENT-DACQHE-CKNTFGSYQCICPPGYQLTHNGKTC 576
Query: 636 ID 637
D
Sbjct: 577 QD 578
Score = 122 bits (295), Expect = 4e-27
Identities = 70/179 (39%), Positives = 94/179 (52%), Gaps = 16/179 (8%)
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTFR 523
S V++D ++ + S ++G QC GFT C D DECA G C+
Sbjct: 285 SSVESDYNQIEETLGFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECAAGNP-CSHS 343
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA---CENVVGSYIC--KCPE 578
CHN G++ C+CP G +AADG C+DIDEC C HA C+N +GSY C +C
Sbjct: 344 CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTC-HAGQDCDNTIGSYRCVVRCGS 402
Query: 579 GYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
G+RRTS +C+DINEC+E C C N GSF C C+ G++ G C+D
Sbjct: 403 GFRRTS----DGLSCQDINECQESSP-CHQR-CFNAIGSFHCGCEPGYQLK--GRKCMD 453
Score = 97.5 bits (232), Expect = 2e-19
Identities = 48/101 (47%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Query: 759 APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDC--LCRTGYELDEDG 816
A G F C C PGY+ G C DV+EC DQ C NT G Y C LC G E+G
Sbjct: 432 AIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 491
Query: 817 ANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRG 855
C D+DEC+ TH C+ QIC NT GSY C C GY +G
Sbjct: 492 -TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQG 531
Score = 94.7 bits (225), Expect = 1e-18
Identities = 51/125 (40%), Positives = 68/125 (54%), Gaps = 12/125 (9%)
Query: 746 ADVDECAA---IPGLC--APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCD--QLCH 796
AD DECAA C A G + C C G A G C D+DECA+ C Q C
Sbjct: 329 ADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCD 388
Query: 797 NTDGSYDCL--CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
NT GSY C+ C +G+ DG +C+D++EC+ ++ C Q C N GS+ C CE GY+ +
Sbjct: 389 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 447
Query: 855 GDACV 859
G C+
Sbjct: 448 GRKCM 452
Score = 89.8 bits (213), Expect = 4e-17
Identities = 42/100 (42%), Positives = 56/100 (56%), Gaps = 8/100 (8%)
Query: 761 GRFRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
G +RCVC GYR G C D+DEC C C NT GSY C+C GY+L +G
Sbjct: 517 GSYRCVCPRGYRSQGVGRPCMDIDECE-NTDACQHECKNTFGSYQCICPPGYQLTHNGKT 575
Query: 819 CRDVDEC-ERDTHT-CQQICSNTEGSYEC---SCEDGYEK 853
C+D+DEC E++ H ++C N GSY+C C Y++
Sbjct: 576 CQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 615
Score = 88.2 bits (209), Expect = 1e-16
Identities = 48/119 (40%), Positives = 61/119 (51%), Gaps = 16/119 (13%)
Query: 747 DVDECAAIPGLCAP--------GRFRCV--CGPGYRPAGE-VCADVDECAVRPPPC--DQ 793
DV+EC +C P G ++C+ C G A C D+DEC C +Q
Sbjct: 453 DVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQ 510
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+C NT GSY C+C GY G C D+DECE +T CQ C NT GSY+C C GY+
Sbjct: 511 ICENTRGSYRCVCPRGYRSQGVGRPCMDIDECE-NTDACQHECKNTFGSYQCICPPGYQ 568
Score = 85.4 bits (202), Expect = 8e-16
Identities = 41/97 (42%), Positives = 48/97 (49%), Gaps = 5/97 (5%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 823
+C G G CAD DECA P C CHN G+Y C C G + DG C+D+D
Sbjct: 314 QCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDID 372
Query: 824 ECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD 856
EC HTC Q C NT GSY C C G+ + D
Sbjct: 373 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSD 409
>AF525689-1|AAN77133.1| 988|Homo sapiens signal
peptide-CUB-EGF-like domain containing protein 1
protein.
Length = 988
Score = 207 bits (505), Expect = 1e-52
Identities = 142/430 (33%), Positives = 189/430 (43%), Gaps = 50/430 (11%)
Query: 231 VDVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDG 289
VDV+EC EG C + C+N S++C C PGY +G+ C D+DEC+ + G
Sbjct: 32 VDVDECSEGTDDCHIDAICQNAPKSYKCLCKPGYK--GEGKQCGDIDECENDYYNGGCVH 89
Query: 290 NPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
C N G Y C+C G+ L G C+D DEC++ C C N G Y C+C +G
Sbjct: 90 E--CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSG 146
Query: 348 WRFDKTAAVCVDERKE--LCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
+ C+ E C ++ + G H C E G C+ P
Sbjct: 147 FFLSDNQHTCIHRSNEGMNCMNK-DHGCAH------------ICRETPKGGVACDCRPGF 193
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
D A+ + C LT C C C +TD C C Y DG +
Sbjct: 194 DLAQNQKDC-------TLT-----CNYGNGGCQHS-CEDTDTGPTCGCHQKYAPHSDGRT 240
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRC 524
C++ CA++ C TC +T G C C GFT PD +TC D++EC C C
Sbjct: 241 CIET--CAVNNGGCDR-TCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFC 297
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTS 584
NT GSF C C GY + D C+DIDEC E R C H C N GS+ C C GY
Sbjct: 298 RNTVGSFECGCRKGYKLLTDERTCQDIDECSFE-RTCDHICINSPGSFQCLCHRGYILYG 356
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCY 644
C D++EC C G C+NT GS+ C C G + DC++ TG C
Sbjct: 357 TTH-----CGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNRKDCVE--TGKCL 408
Query: 645 -RSLVSGRCE 653
R+ S R +
Sbjct: 409 SRAKTSPRAQ 418
Score = 188 bits (458), Expect = 7e-47
Identities = 142/436 (32%), Positives = 187/436 (42%), Gaps = 55/436 (12%)
Query: 191 DVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE----GGMVCRN 245
DVDECS C + C+N P +Y C C G+K G C D++EC GG V
Sbjct: 33 DVDECSEGTDDCHIDAICQNAPKSYKCLCKPGYK-GEGKQCGDIDECENDYYNGGCV--- 88
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C N G++RC C G+ L DG NC DVDEC + C + C N G YEC C
Sbjct: 89 HECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ----ICVNAMGSYECQCH 144
Query: 306 AGWKLVGRR--CVDRDE----CKELPYVCAGGECRNF-NGGYVCECPAGWRFDKTAAVCV 358
+G+ L + C+ R C + CA CR GG C+C G+ + C
Sbjct: 145 SGFFLSDNQHTCIHRSNEGMNCMNKDHGCAH-ICRETPKGGVACDCRPGFDLAQNQKDCT 203
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAW---GRYC-ERCPA---------P 405
L + G H P C C + A GR C E C
Sbjct: 204 -----LTCNYGNGGCQHSCEDTDTG-PTCGCHQKYAPHSDGRTCIETCAVNNGGCDRTCK 257
Query: 406 DSAEFMRI-CQGGMG-RPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAP 461
D+A +R C G +P+ +D++EC V C C NT GSF C C GY L
Sbjct: 258 DTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGC-DHFCRNTVGSFECGCRKGYKLLT 316
Query: 462 DGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCT 521
D +C D DEC+ + R C + C N+ G ++C C G+ C DVDEC+ SC
Sbjct: 317 DERTCQDIDECSFE-RTCDH-ICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCD 374
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA---CENVVGSYIC--KC 576
C NT GS+ C CP G + + C + +C+ + P A C G C C
Sbjct: 375 QGCVNTKGSYECVCPPGRRLHWNRKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCFLSC 434
Query: 577 PEGYRRTSAPQDSENA 592
P T DSEN+
Sbjct: 435 P---AHTLFVPDSENS 447
Score = 161 bits (390), Expect = 1e-38
Identities = 137/448 (30%), Positives = 183/448 (40%), Gaps = 65/448 (14%)
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRI---CDHG 165
DVDECS G C A C N P +++C C PGY+ +C D+DEC + C H
Sbjct: 33 DVDECSEGTDDCHIDAICQNAPKSYKCLCKPGYK--GEGKQCGDIDECENDYYNGGCVH- 89
Query: 166 DCRNTIGSYRCECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK 223
+C N G+YRC C G+ L + C DVDEC C+ C N G+Y C C GF
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSGFF 148
Query: 224 AGPNNDCVDVNECREGGMVCRNGR------CRNT-VGSFRCECAPGYTLTADGRNCRDVD 276
N ++ E GM C N CR T G C+C PG+ L + ++C
Sbjct: 149 LSDNQHTC-IHRSNE-GMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDC--TL 204
Query: 277 ECDELPHPCGRDGNPSCTNTNGGYECSCGAGW--KLVGRRCVDRDECKELPYVCAGGECR 334
C+ C SC +T+ G C C + GR C+ + C C C+
Sbjct: 205 TCNYGNGGC----QHSCEDTDTGPTCGCHQKYAPHSDGRTCI--ETCAVNNGGC-DRTCK 257
Query: 335 NFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAA 394
+ G C CP G+ C D + L + G C + EC C +G
Sbjct: 258 DTATGVRCSCPVGFTLQPDGKTCKDINECLVNN----GGCDHFCRNTVGSFECGCRKGYK 313
Query: 395 WGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECP 454
D R CQ D+DEC C C+N+ GSF+C C
Sbjct: 314 L--------LTDE----RTCQ----------DIDECSFE-RTC-DHICINSPGSFQCLCH 349
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPG-FTQGPDQTCVDVDEC 513
GY+L C D DEC++ C G C NT+G YEC C PG + CV+ +C
Sbjct: 350 RGYILY-GTTHCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNRKDCVETGKC 407
Query: 514 ---AEGRASCTFRCHNTAGSFRC--TCP 536
A+ C G C +CP
Sbjct: 408 LSRAKTSPRAQLSCSKAGGVESCFLSCP 435
Score = 149 bits (361), Expect = 4e-35
Identities = 125/440 (28%), Positives = 171/440 (38%), Gaps = 57/440 (12%)
Query: 68 IDECDIMPQLCK-PGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
+DEC C C + P ++C C GY+ + C D+DEC + +C
Sbjct: 34 VDECSEGTDDCHIDAICQNAPKSYKCLCKPGYKGEGKQ--CGDIDECENDYYNGGCVHEC 91
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
+N+PG + C C G+ L C DVDEC D C N +GSY C+C G+ L +
Sbjct: 92 INIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSD 151
Query: 187 N--VC----RDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREG 239
N C + C C + E G C C GF N DC C G
Sbjct: 152 NQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDC--TLTCNYG 209
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGG 299
C++ C +T C C Y +DGR C ++ C C R +C +T G
Sbjct: 210 NGGCQHS-CEDTDTGPTCGCHQKYAPHSDGRTC--IETCAVNNGGCDR----TCKDTATG 262
Query: 300 YECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVC 357
CSC G+ L G+ C D +EC C CRN G + C C G++ +
Sbjct: 263 VRCSCPVGFTLQPDGKTCKDINECLVNNGGC-DHFCRNTVGSFECGCRKGYK------LL 315
Query: 358 VDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG 417
DER C D EC ++ R C+ F +C G
Sbjct: 316 TDER--TCQD----------------IDEC------SFERTCDHICINSPGSFQCLCHRG 351
Query: 418 MGRPNLTQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
T D+DEC + C G CVNT GS+ C CP G L + CV+ +C
Sbjct: 352 YILYGTTHCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNRKDCVETGKCLSR 410
Query: 476 PRICGNG--TCSNTRGGYEC 493
+ +CS G C
Sbjct: 411 AKTSPRAQLSCSKAGGVESC 430
Score = 108 bits (259), Expect = 9e-23
Identities = 51/115 (44%), Positives = 64/115 (55%), Gaps = 10/115 (8%)
Query: 747 DVDECAA------IPGLC--APGRFRCVCGPGYRPAGEVCADVDECA--VRPPPCDQLCH 796
DVDEC+ I +C AP ++C+C PGY+ G+ C D+DEC C C
Sbjct: 33 DVDECSEGTDDCHIDAICQNAPKSYKCLCKPGYKGEGKQCGDIDECENDYYNGGCVHECI 92
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
N G+Y C C G+ L DG NC DVDEC+ + CQQIC N GSYEC C G+
Sbjct: 93 NIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGF 147
Score = 99.1 bits (236), Expect = 6e-20
Identities = 41/90 (45%), Positives = 55/90 (61%), Gaps = 3/90 (3%)
Query: 764 RCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 821
RC C G+ +P G+ C D++EC V CD C NT GS++C CR GY+L D C+D
Sbjct: 264 RCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQD 323
Query: 822 VDECERDTHTCQQICSNTEGSYECSCEDGY 851
+DEC + TC IC N+ GS++C C GY
Sbjct: 324 IDECSFE-RTCDHICINSPGSFQCLCHRGY 352
Score = 91.9 bits (218), Expect = 9e-18
Identities = 46/112 (41%), Positives = 58/112 (51%), Gaps = 10/112 (8%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNT 798
D++EC G C G F C C GY+ + C D+DEC+ CD +C N+
Sbjct: 282 DINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERT-CDHICINS 340
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
GS+ CLC GY L +C DVDEC +C Q C NT+GSYEC C G
Sbjct: 341 PGSFQCLCHRGYIL-YGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPG 391
Score = 79.8 bits (188), Expect = 4e-14
Identities = 32/88 (36%), Positives = 44/88 (50%)
Query: 765 CVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDE 824
C C Y P + ++ CAV CD+ C +T C C G+ L DG C+D++E
Sbjct: 226 CGCHQKYAPHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINE 285
Query: 825 CERDTHTCQQICSNTEGSYECSCEDGYE 852
C + C C NT GS+EC C GY+
Sbjct: 286 CLVNNGGCDHFCRNTVGSFECGCRKGYK 313
Score = 75.8 bits (178), Expect = 6e-13
Identities = 36/100 (36%), Positives = 48/100 (48%), Gaps = 7/100 (7%)
Query: 760 PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG +RC C G+ A G C DVDEC C Q+C N GSY+C C +G+ L ++
Sbjct: 95 PGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQH 154
Query: 818 NC----RDVDECERDTHTCQQICSNT-EGSYECSCEDGYE 852
C + C H C IC T +G C C G++
Sbjct: 155 TCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFD 194
Score = 72.9 bits (171), Expect = 4e-12
Identities = 39/108 (36%), Positives = 55/108 (50%), Gaps = 9/108 (8%)
Query: 747 DVDECA---AIPGLC--APGRFRCVCGPGYRPAGEV-CADVDECAVRPPPCDQLCHNTDG 800
D+DEC+ +C +PG F+C+C GY G C DVDEC++ CDQ C NT G
Sbjct: 323 DIDECSFERTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKG 382
Query: 801 SYDCLCRTGYELDEDGANCRDVDEC---ERDTHTCQQICSNTEGSYEC 845
SY+C+C G L + +C + +C + + Q CS G C
Sbjct: 383 SYECVCPPGRRLHWNRKDCVETGKCLSRAKTSPRAQLSCSKAGGVESC 430
Score = 49.2 bits (112), Expect = 6e-05
Identities = 29/106 (27%), Positives = 38/106 (35%), Gaps = 2/106 (1%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
CA I G C C PG+ A C C C +TD C C Y
Sbjct: 173 CAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKY 232
Query: 811 ELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
DG C ++ C + C + C +T CSC G+ + D
Sbjct: 233 APHSDGRTC--IETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPD 276
Score = 42.7 bits (96), Expect = 0.005
Identities = 18/40 (45%), Positives = 21/40 (52%), Gaps = 2/40 (5%)
Query: 821 DVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDAC 858
DVDEC T C IC N SY+C C+ GY+ G C
Sbjct: 33 DVDECSEGTDDCHIDAICQNAPKSYKCLCKPGYKGEGKQC 72
>Z97832-1|CAI20187.1| 993|Homo sapiens protein ( Human DNA sequence
from clone RP3-329A5 on chromosome 6p21.1-21.33. ).
Length = 993
Score = 206 bits (503), Expect = 3e-52
Identities = 140/417 (33%), Positives = 189/417 (45%), Gaps = 57/417 (13%)
Query: 232 DVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHP-CGRDG 289
DV+EC EG C + C+NT S++C C GYT DG++C+DVDEC+ + C D
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDNAGCVHD- 85
Query: 290 NPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
C N G Y C+C G+ L G C+D DEC E C C N G Y C C G
Sbjct: 86 ---CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREG 141
Query: 348 WRFDKTAAVCVDERKE--LCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
+ C+ +E C ++ G H C E G CE
Sbjct: 142 FFLSDNQHTCIQRPEEGMNCMNK-NHGCAH------------ICRETPKGGIACE----- 183
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGG---RCVNTDGSFRCECPDGYVLAPD 462
C+ G LT++ +C++ + GG C +T+ RC C +VL D
Sbjct: 184 --------CRPGF---ELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTD 232
Query: 463 GLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCT 521
G +C++ CA++ C + C + G C C GF PD+ TC D+DEC C
Sbjct: 233 GKTCIET--CAVNNGGC-DSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCD 289
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C NT GSF C+C GY + + +C+DIDEC + R C H C N GS+ C C GY
Sbjct: 290 HICRNTVGSFECSCKKGYKLLINERNCQDIDECSFD-RTCDHICVNTPGSFQCLCHRGYL 348
Query: 582 RTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSE-DGTDCID 637
C D++EC C G CINT GS+ C C AG +G DC +
Sbjct: 349 LYGITH-----CGDVDECSINRGGCRFG-CINTPGSYQCTCPAGQGRLHWNGKDCTE 399
Score = 198 bits (482), Expect = 9e-50
Identities = 135/390 (34%), Positives = 175/390 (44%), Gaps = 31/390 (7%)
Query: 190 RDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNEC-REGGMVCRNGR 247
+DVDEC C + C+N P +Y C C G+ G C DV+EC RE C +
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY-TGDGKHCKDVDECEREDNAGCVHD- 85
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
C N G++RC C G+ L DG NC DVDEC E C + SC N G YEC C G
Sbjct: 86 CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQ----SCVNMMGSYECHCREG 141
Query: 308 WKLVGRR--CVDRDE----CKELPYVCAGGECRNF-NGGYVCECPAGWRFDKTAAVCV-- 358
+ L + C+ R E C + CA CR GG CEC G+ K C
Sbjct: 142 FFLSDNQHTCIQRPEEGMNCMNKNHGCAH-ICRETPKGGIACECRPGFELTKNQRDCKLT 200
Query: 359 -----DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRY-CE-RCPAPDSAEFM 411
+ C D + RC L C E A C+ +C +
Sbjct: 201 CNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHC 260
Query: 412 RICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
G M +P+ +D+DECR+ C C NT GSF C C GY L + +C D
Sbjct: 261 TCPVGFMLQPDRKTCKDIDECRLNNGGC-DHICRNTVGSFECSCKKGYKLLINERNCQDI 319
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAG 529
DEC+ D R C + C NT G ++C C G+ C DVDEC+ R C F C NT G
Sbjct: 320 DECSFD-RTCDH-ICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTPG 377
Query: 530 SFRCTCPYGYA-VAADGVHCRDIDECVQEP 558
S++CTCP G + +G C + +C P
Sbjct: 378 SYQCTCPAGQGRLHWNGKDCTEPLKCQGSP 407
Score = 162 bits (394), Expect = 4e-39
Identities = 128/421 (30%), Positives = 182/421 (43%), Gaps = 46/421 (10%)
Query: 104 SHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC--GDQRI 161
S +DVDEC G C A C N P +++C C GY T C+DVDEC D
Sbjct: 24 SKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDECEREDNAG 81
Query: 162 CDHGDCRNTIGSYRCECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCD 219
C H DC N G+YRC C G+ L + C DVDEC+ C+ +C N+ G+Y CHC
Sbjct: 82 CVH-DCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQ-SCVNMMGSYECHCR 139
Query: 220 DGFKAGPN-NDCVDVNECREGGMVCRNGR------CRNT-VGSFRCECAPGYTLTADGRN 271
+GF N + C+ + E GM C N CR T G CEC PG+ LT + R+
Sbjct: 140 EGFFLSDNQHTCI---QRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRD 196
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCA 329
C+ C+ C +C +T G C C + L G+ C+ + C C
Sbjct: 197 CKLT--CNYGNGGC----QHTCDDTEQGPRCGCHIKFVLHTDGKTCI--ETCAVNNGGC- 247
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVC--VDERK-------ELCYDEWEAGRCHRARPL 380
+C + G C CP G+ C +DE + +C + + C +
Sbjct: 248 DSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGY 307
Query: 381 QLARPECCCS--EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ--DLDECRVRPDV 436
+L E C + ++ R C+ F +C G +T D+DEC +
Sbjct: 308 KLLINERNCQDIDECSFDRTCDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGG 367
Query: 437 CVGGRCVNTDGSFRCECPDGY-VLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQC 495
C G C+NT GS++C CP G L +G C + +C P S R G + C
Sbjct: 368 CRFG-CINTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQGSPG-ASKAMLSCNRSGKKDTC 425
Query: 496 S 496
+
Sbjct: 426 A 426
Score = 138 bits (334), Expect = 8e-32
Identities = 92/285 (32%), Positives = 124/285 (43%), Gaps = 16/285 (5%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWG-RPPCRGMAQ- 125
+DEC C+ +C + ++C C G+ + H C E G A
Sbjct: 113 VDECAEGNGGCQQ-SCVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHI 171
Query: 126 CVNLP-GAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
C P G C C PG+ LT + +C+ G+ C H C +T RC C + L
Sbjct: 172 CRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGG-CQH-TCDDTEQGPRCGCHIKFVL 229
Query: 185 RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVC 243
+ ++ C+ C + C + C C GF P+ C D++ECR C
Sbjct: 230 HTDGKTCIETCAVNNGGC-DSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGC 288
Query: 244 RNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS 303
+ CRNTVGSF C C GY L + RNC+D+DEC R + C NT G ++C
Sbjct: 289 DH-ICRNTVGSFECSCKKGYKLLINERNCQDIDECS-----FDRTCDHICVNTPGSFQCL 342
Query: 304 CGAGWKLVG-RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
C G+ L G C D DEC C G C N G Y C CPAG
Sbjct: 343 CHRGYLLYGITHCGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 386
Score = 106 bits (255), Expect = 3e-22
Identities = 54/133 (40%), Positives = 70/133 (52%), Gaps = 10/133 (7%)
Query: 509 DVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRV-CPHAC 565
DVDEC EG +C C NT S++C C GY DG HC+D+DEC +E C H C
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDNAGCVHDC 86
Query: 566 ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
N+ G+Y C C +G+ D N C D++EC E C C+N GS+ C C G
Sbjct: 87 VNIPGNYRCTCYDGFHLA---HDGHN-CLDVDECAEGNGGCQQS-CVNMMGSYECHCREG 141
Query: 626 FEPSEDGTDCIDR 638
F S++ CI R
Sbjct: 142 FFLSDNQHTCIQR 154
Score = 100 bits (240), Expect = 2e-20
Identities = 49/114 (42%), Positives = 58/114 (50%), Gaps = 9/114 (7%)
Query: 747 DVDECAA------IPGLC--APGRFRCVCGPGYRPAGEVCADVDECAVRPPP-CDQLCHN 797
DVDEC I +C P ++C+C GY G+ C DVDEC C C N
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHDCVN 88
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G+Y C C G+ L DG NC DVDEC CQQ C N GSYEC C +G+
Sbjct: 89 IPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGF 142
Score = 98.7 bits (235), Expect = 8e-20
Identities = 40/89 (44%), Positives = 55/89 (61%), Gaps = 3/89 (3%)
Query: 765 CVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDV 822
C C G+ +P + C D+DEC + CD +C NT GS++C C+ GY+L + NC+D+
Sbjct: 260 CTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDI 319
Query: 823 DECERDTHTCQQICSNTEGSYECSCEDGY 851
DEC D TC IC NT GS++C C GY
Sbjct: 320 DECSFD-RTCDHICVNTPGSFQCLCHRGY 347
Score = 86.2 bits (204), Expect = 4e-16
Identities = 46/112 (41%), Positives = 57/112 (50%), Gaps = 10/112 (8%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNT 798
D+DEC G C G F C C GY+ C D+DEC+ CD +C NT
Sbjct: 277 DIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSF-DRTCDHICVNT 335
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
GS+ CLC GY L +C DVDEC + C+ C NT GSY+C+C G
Sbjct: 336 PGSFQCLCHRGYLL-YGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAG 386
Score = 81.4 bits (192), Expect = 1e-14
Identities = 42/106 (39%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 754 IPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYE 811
+PGLC Y A + DVDEC C D +C NT SY C+C++GY
Sbjct: 6 VPGLCLLVLLVHARAAQYSKAAQ---DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT 62
Query: 812 LDEDGANCRDVDECERDTHT-CQQICSNTEGSYECSCEDGYEKRGD 856
DG +C+DVDECER+ + C C N G+Y C+C DG+ D
Sbjct: 63 --GDGKHCKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHD 106
Score = 80.6 bits (190), Expect = 2e-14
Identities = 32/78 (41%), Positives = 43/78 (55%), Gaps = 2/78 (2%)
Query: 775 GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ 834
G+ C ++ CAV CD CH+ C C G+ L D C+D+DEC + C
Sbjct: 233 GKTC--IETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDH 290
Query: 835 ICSNTEGSYECSCEDGYE 852
IC NT GS+ECSC+ GY+
Sbjct: 291 ICRNTVGSFECSCKKGYK 308
Score = 79.8 bits (188), Expect = 4e-14
Identities = 47/120 (39%), Positives = 55/120 (45%), Gaps = 14/120 (11%)
Query: 747 DVDEC-----AAIPGLCA--PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
DVDEC A C PG +RC C G+ A G C DVDECA C Q C N
Sbjct: 70 DVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVN 129
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDE----CERDTHTCQQICSNT-EGSYECSCEDGYE 852
GSY+C CR G+ L ++ C E C H C IC T +G C C G+E
Sbjct: 130 MMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFE 189
Score = 43.2 bits (97), Expect = 0.004
Identities = 19/41 (46%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Query: 820 RDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDAC 858
+DVDEC T C IC NT SY+C C+ GY G C
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHC 68
Score = 41.5 bits (93), Expect = 0.012
Identities = 25/106 (23%), Positives = 36/106 (33%), Gaps = 2/106 (1%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
CA I G C C PG+ C C C +T+ C C +
Sbjct: 168 CAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKF 227
Query: 811 ELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
L DG C ++ C + C C + C+C G+ + D
Sbjct: 228 VLHTDGKTC--IETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPD 271
Score = 37.5 bits (83), Expect = 0.20
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 592 ACEDINECEEQEDLCS-GGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
A +D++EC E D C +C NT S+ C C +G+ + DG C D
Sbjct: 26 AAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKD 70
>AY639608-1|AAU08347.1| 993|Homo sapiens signal peptide, CUB and
EGF-like domain containing protein 3 protein.
Length = 993
Score = 206 bits (503), Expect = 3e-52
Identities = 140/417 (33%), Positives = 189/417 (45%), Gaps = 57/417 (13%)
Query: 232 DVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHP-CGRDG 289
DV+EC EG C + C+NT S++C C GYT DG++C+DVDEC+ + C D
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDNAGCVHD- 85
Query: 290 NPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
C N G Y C+C G+ L G C+D DEC E C C N G Y C C G
Sbjct: 86 ---CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREG 141
Query: 348 WRFDKTAAVCVDERKE--LCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
+ C+ +E C ++ G H C E G CE
Sbjct: 142 FFLSDNQHTCIQRPEEGMNCMNK-NHGCAH------------ICRETPKGGIACE----- 183
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGG---RCVNTDGSFRCECPDGYVLAPD 462
C+ G LT++ +C++ + GG C +T+ RC C +VL D
Sbjct: 184 --------CRPGF---ELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTD 232
Query: 463 GLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCT 521
G +C++ CA++ C + C + G C C GF PD+ TC D+DEC C
Sbjct: 233 GKTCIET--CAVNNGGC-DSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCD 289
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C NT GSF C+C GY + + +C+DIDEC + R C H C N GS+ C C GY
Sbjct: 290 HICRNTVGSFECSCKKGYKLLINERNCQDIDECSFD-RTCDHICVNTPGSFQCLCHRGYL 348
Query: 582 RTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSE-DGTDCID 637
C D++EC C G CINT GS+ C C AG +G DC +
Sbjct: 349 LYGITH-----CGDVDECSINRGGCRFG-CINTPGSYQCTCPAGQGRLHWNGKDCTE 399
Score = 198 bits (482), Expect = 9e-50
Identities = 135/390 (34%), Positives = 175/390 (44%), Gaps = 31/390 (7%)
Query: 190 RDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNEC-REGGMVCRNGR 247
+DVDEC C + C+N P +Y C C G+ G C DV+EC RE C +
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY-TGDGKHCKDVDECEREDNAGCVHD- 85
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
C N G++RC C G+ L DG NC DVDEC E C + SC N G YEC C G
Sbjct: 86 CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQ----SCVNMMGSYECHCREG 141
Query: 308 WKLVGRR--CVDRDE----CKELPYVCAGGECRNF-NGGYVCECPAGWRFDKTAAVCV-- 358
+ L + C+ R E C + CA CR GG CEC G+ K C
Sbjct: 142 FFLSDNQHTCIQRPEEGMNCMNKNHGCAH-ICRETPKGGIACECRPGFELTKNQRDCKLT 200
Query: 359 -----DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRY-CE-RCPAPDSAEFM 411
+ C D + RC L C E A C+ +C +
Sbjct: 201 CNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHC 260
Query: 412 RICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
G M +P+ +D+DECR+ C C NT GSF C C GY L + +C D
Sbjct: 261 TCPVGFMLQPDRKTCKDIDECRLNNGGC-DHICRNTVGSFECSCKKGYKLLINERNCQDI 319
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAG 529
DEC+ D R C + C NT G ++C C G+ C DVDEC+ R C F C NT G
Sbjct: 320 DECSFD-RTCDH-ICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTPG 377
Query: 530 SFRCTCPYGYA-VAADGVHCRDIDECVQEP 558
S++CTCP G + +G C + +C P
Sbjct: 378 SYQCTCPAGQGRLHWNGKDCTEPLKCQGSP 407
Score = 162 bits (394), Expect = 4e-39
Identities = 128/421 (30%), Positives = 182/421 (43%), Gaps = 46/421 (10%)
Query: 104 SHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC--GDQRI 161
S +DVDEC G C A C N P +++C C GY T C+DVDEC D
Sbjct: 24 SKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDECEREDNAG 81
Query: 162 CDHGDCRNTIGSYRCECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCD 219
C H DC N G+YRC C G+ L + C DVDEC+ C+ +C N+ G+Y CHC
Sbjct: 82 CVH-DCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQ-SCVNMMGSYECHCR 139
Query: 220 DGFKAGPN-NDCVDVNECREGGMVCRNGR------CRNT-VGSFRCECAPGYTLTADGRN 271
+GF N + C+ + E GM C N CR T G CEC PG+ LT + R+
Sbjct: 140 EGFFLSDNQHTCI---QRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRD 196
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCA 329
C+ C+ C +C +T G C C + L G+ C+ + C C
Sbjct: 197 CKLT--CNYGNGGC----QHTCDDTEQGPRCGCHIKFVLHTDGKTCI--ETCAVNNGGC- 247
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVC--VDERK-------ELCYDEWEAGRCHRARPL 380
+C + G C CP G+ C +DE + +C + + C +
Sbjct: 248 DSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGY 307
Query: 381 QLARPECCCS--EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ--DLDECRVRPDV 436
+L E C + ++ R C+ F +C G +T D+DEC +
Sbjct: 308 KLLINERNCQDIDECSFDRTCDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGG 367
Query: 437 CVGGRCVNTDGSFRCECPDGY-VLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQC 495
C G C+NT GS++C CP G L +G C + +C P S R G + C
Sbjct: 368 CRFG-CINTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQGSPG-ASKAMLSCNRSGKKDTC 425
Query: 496 S 496
+
Sbjct: 426 A 426
Score = 138 bits (334), Expect = 8e-32
Identities = 92/285 (32%), Positives = 124/285 (43%), Gaps = 16/285 (5%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWG-RPPCRGMAQ- 125
+DEC C+ +C + ++C C G+ + H C E G A
Sbjct: 113 VDECAEGNGGCQQ-SCVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHI 171
Query: 126 CVNLP-GAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
C P G C C PG+ LT + +C+ G+ C H C +T RC C + L
Sbjct: 172 CRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGG-CQH-TCDDTEQGPRCGCHIKFVL 229
Query: 185 RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVC 243
+ ++ C+ C + C + C C GF P+ C D++ECR C
Sbjct: 230 HTDGKTCIETCAVNNGGC-DSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGC 288
Query: 244 RNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS 303
+ CRNTVGSF C C GY L + RNC+D+DEC R + C NT G ++C
Sbjct: 289 DH-ICRNTVGSFECSCKKGYKLLINERNCQDIDECS-----FDRTCDHICVNTPGSFQCL 342
Query: 304 CGAGWKLVG-RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
C G+ L G C D DEC C G C N G Y C CPAG
Sbjct: 343 CHRGYLLYGITHCGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 386
Score = 106 bits (255), Expect = 3e-22
Identities = 54/133 (40%), Positives = 70/133 (52%), Gaps = 10/133 (7%)
Query: 509 DVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRV-CPHAC 565
DVDEC EG +C C NT S++C C GY DG HC+D+DEC +E C H C
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDNAGCVHDC 86
Query: 566 ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
N+ G+Y C C +G+ D N C D++EC E C C+N GS+ C C G
Sbjct: 87 VNIPGNYRCTCYDGFHLA---HDGHN-CLDVDECAEGNGGCQQS-CVNMMGSYECHCREG 141
Query: 626 FEPSEDGTDCIDR 638
F S++ CI R
Sbjct: 142 FFLSDNQHTCIQR 154
Score = 100 bits (240), Expect = 2e-20
Identities = 49/114 (42%), Positives = 58/114 (50%), Gaps = 9/114 (7%)
Query: 747 DVDECAA------IPGLC--APGRFRCVCGPGYRPAGEVCADVDECAVRPPP-CDQLCHN 797
DVDEC I +C P ++C+C GY G+ C DVDEC C C N
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHDCVN 88
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G+Y C C G+ L DG NC DVDEC CQQ C N GSYEC C +G+
Sbjct: 89 IPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGF 142
Score = 98.7 bits (235), Expect = 8e-20
Identities = 40/89 (44%), Positives = 55/89 (61%), Gaps = 3/89 (3%)
Query: 765 CVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDV 822
C C G+ +P + C D+DEC + CD +C NT GS++C C+ GY+L + NC+D+
Sbjct: 260 CTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDI 319
Query: 823 DECERDTHTCQQICSNTEGSYECSCEDGY 851
DEC D TC IC NT GS++C C GY
Sbjct: 320 DECSFD-RTCDHICVNTPGSFQCLCHRGY 347
Score = 86.2 bits (204), Expect = 4e-16
Identities = 46/112 (41%), Positives = 57/112 (50%), Gaps = 10/112 (8%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNT 798
D+DEC G C G F C C GY+ C D+DEC+ CD +C NT
Sbjct: 277 DIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSF-DRTCDHICVNT 335
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
GS+ CLC GY L +C DVDEC + C+ C NT GSY+C+C G
Sbjct: 336 PGSFQCLCHRGYLL-YGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAG 386
Score = 81.4 bits (192), Expect = 1e-14
Identities = 42/106 (39%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 754 IPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYE 811
+PGLC Y A + DVDEC C D +C NT SY C+C++GY
Sbjct: 6 VPGLCLLVLLVHARAAQYSKAAQ---DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT 62
Query: 812 LDEDGANCRDVDECERDTHT-CQQICSNTEGSYECSCEDGYEKRGD 856
DG +C+DVDECER+ + C C N G+Y C+C DG+ D
Sbjct: 63 --GDGKHCKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHD 106
Score = 80.6 bits (190), Expect = 2e-14
Identities = 32/78 (41%), Positives = 43/78 (55%), Gaps = 2/78 (2%)
Query: 775 GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ 834
G+ C ++ CAV CD CH+ C C G+ L D C+D+DEC + C
Sbjct: 233 GKTC--IETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDH 290
Query: 835 ICSNTEGSYECSCEDGYE 852
IC NT GS+ECSC+ GY+
Sbjct: 291 ICRNTVGSFECSCKKGYK 308
Score = 79.8 bits (188), Expect = 4e-14
Identities = 47/120 (39%), Positives = 55/120 (45%), Gaps = 14/120 (11%)
Query: 747 DVDEC-----AAIPGLCA--PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
DVDEC A C PG +RC C G+ A G C DVDECA C Q C N
Sbjct: 70 DVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVN 129
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDE----CERDTHTCQQICSNT-EGSYECSCEDGYE 852
GSY+C CR G+ L ++ C E C H C IC T +G C C G+E
Sbjct: 130 MMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFE 189
Score = 43.2 bits (97), Expect = 0.004
Identities = 19/41 (46%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Query: 820 RDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDAC 858
+DVDEC T C IC NT SY+C C+ GY G C
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHC 68
Score = 41.5 bits (93), Expect = 0.012
Identities = 25/106 (23%), Positives = 36/106 (33%), Gaps = 2/106 (1%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
CA I G C C PG+ C C C +T+ C C +
Sbjct: 168 CAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKF 227
Query: 811 ELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
L DG C ++ C + C C + C+C G+ + D
Sbjct: 228 VLHTDGKTC--IETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPD 271
Score = 37.5 bits (83), Expect = 0.20
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 592 ACEDINECEEQEDLCS-GGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
A +D++EC E D C +C NT S+ C C +G+ + DG C D
Sbjct: 26 AAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKD 70
>AF452494-1|AAN76808.1| 993|Homo sapiens CUB and EGF containing
protein protein.
Length = 993
Score = 206 bits (503), Expect = 3e-52
Identities = 140/417 (33%), Positives = 189/417 (45%), Gaps = 57/417 (13%)
Query: 232 DVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHP-CGRDG 289
DV+EC EG C + C+NT S++C C GYT DG++C+DVDEC+ + C D
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDNAGCVHD- 85
Query: 290 NPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
C N G Y C+C G+ L G C+D DEC E C C N G Y C C G
Sbjct: 86 ---CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREG 141
Query: 348 WRFDKTAAVCVDERKE--LCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
+ C+ +E C ++ G H C E G CE
Sbjct: 142 FFLSDNQHTCIQRPEEGMNCMNK-NHGCAH------------ICRETPKGGIACE----- 183
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGG---RCVNTDGSFRCECPDGYVLAPD 462
C+ G LT++ +C++ + GG C +T+ RC C +VL D
Sbjct: 184 --------CRPGF---ELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTD 232
Query: 463 GLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCT 521
G +C++ CA++ C + C + G C C GF PD+ TC D+DEC C
Sbjct: 233 GKTCIET--CAVNNGGC-DSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCD 289
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C NT GSF C+C GY + + +C+DIDEC + R C H C N GS+ C C GY
Sbjct: 290 HICRNTVGSFECSCKKGYKLLINERNCQDIDECSFD-RTCDHICVNTPGSFQCLCHRGYL 348
Query: 582 RTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSE-DGTDCID 637
C D++EC C G CINT GS+ C C AG +G DC +
Sbjct: 349 LYGITH-----CGDVDECSINRGGCRFG-CINTPGSYQCTCPAGQGRLHWNGKDCTE 399
Score = 198 bits (482), Expect = 9e-50
Identities = 135/390 (34%), Positives = 175/390 (44%), Gaps = 31/390 (7%)
Query: 190 RDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNEC-REGGMVCRNGR 247
+DVDEC C + C+N P +Y C C G+ G C DV+EC RE C +
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY-TGDGKHCKDVDECEREDNAGCVHD- 85
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
C N G++RC C G+ L DG NC DVDEC E C + SC N G YEC C G
Sbjct: 86 CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQ----SCVNMMGSYECHCREG 141
Query: 308 WKLVGRR--CVDRDE----CKELPYVCAGGECRNF-NGGYVCECPAGWRFDKTAAVCV-- 358
+ L + C+ R E C + CA CR GG CEC G+ K C
Sbjct: 142 FFLSDNQHTCIQRPEEGMNCMNKNHGCAH-ICRETPKGGIACECRPGFELTKNQRDCKLT 200
Query: 359 -----DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRY-CE-RCPAPDSAEFM 411
+ C D + RC L C E A C+ +C +
Sbjct: 201 CNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHC 260
Query: 412 RICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
G M +P+ +D+DECR+ C C NT GSF C C GY L + +C D
Sbjct: 261 TCPVGFMLQPDRKTCKDIDECRLNNGGC-DHICRNTVGSFECSCKKGYKLLINERNCQDI 319
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAG 529
DEC+ D R C + C NT G ++C C G+ C DVDEC+ R C F C NT G
Sbjct: 320 DECSFD-RTCDH-ICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTPG 377
Query: 530 SFRCTCPYGYA-VAADGVHCRDIDECVQEP 558
S++CTCP G + +G C + +C P
Sbjct: 378 SYQCTCPAGQGRLHWNGKDCTEPLKCQGSP 407
Score = 162 bits (394), Expect = 4e-39
Identities = 128/421 (30%), Positives = 182/421 (43%), Gaps = 46/421 (10%)
Query: 104 SHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC--GDQRI 161
S +DVDEC G C A C N P +++C C GY T C+DVDEC D
Sbjct: 24 SKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDECEREDNAG 81
Query: 162 CDHGDCRNTIGSYRCECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCD 219
C H DC N G+YRC C G+ L + C DVDEC+ C+ +C N+ G+Y CHC
Sbjct: 82 CVH-DCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQ-SCVNMMGSYECHCR 139
Query: 220 DGFKAGPN-NDCVDVNECREGGMVCRNGR------CRNT-VGSFRCECAPGYTLTADGRN 271
+GF N + C+ + E GM C N CR T G CEC PG+ LT + R+
Sbjct: 140 EGFFLSDNQHTCI---QRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRD 196
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCA 329
C+ C+ C +C +T G C C + L G+ C+ + C C
Sbjct: 197 CKLT--CNYGNGGC----QHTCDDTEQGPRCGCHIKFVLHTDGKTCI--ETCAVNNGGC- 247
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVC--VDERK-------ELCYDEWEAGRCHRARPL 380
+C + G C CP G+ C +DE + +C + + C +
Sbjct: 248 DSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGY 307
Query: 381 QLARPECCCS--EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ--DLDECRVRPDV 436
+L E C + ++ R C+ F +C G +T D+DEC +
Sbjct: 308 KLLINERNCQDIDECSFDRTCDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGG 367
Query: 437 CVGGRCVNTDGSFRCECPDGY-VLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQC 495
C G C+NT GS++C CP G L +G C + +C P S R G + C
Sbjct: 368 CRFG-CINTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQGSPG-ASKAMLSCNRSGKKDTC 425
Query: 496 S 496
+
Sbjct: 426 A 426
Score = 138 bits (334), Expect = 8e-32
Identities = 92/285 (32%), Positives = 124/285 (43%), Gaps = 16/285 (5%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWG-RPPCRGMAQ- 125
+DEC C+ +C + ++C C G+ + H C E G A
Sbjct: 113 VDECAEGNGGCQQ-SCVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHI 171
Query: 126 CVNLP-GAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
C P G C C PG+ LT + +C+ G+ C H C +T RC C + L
Sbjct: 172 CRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGG-CQH-TCDDTEQGPRCGCHIKFVL 229
Query: 185 RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVC 243
+ ++ C+ C + C + C C GF P+ C D++ECR C
Sbjct: 230 HTDGKTCIETCAVNNGGC-DSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGC 288
Query: 244 RNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS 303
+ CRNTVGSF C C GY L + RNC+D+DEC R + C NT G ++C
Sbjct: 289 DH-ICRNTVGSFECSCKKGYKLLINERNCQDIDECS-----FDRTCDHICVNTPGSFQCL 342
Query: 304 CGAGWKLVG-RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
C G+ L G C D DEC C G C N G Y C CPAG
Sbjct: 343 CHRGYLLYGITHCGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 386
Score = 106 bits (255), Expect = 3e-22
Identities = 54/133 (40%), Positives = 70/133 (52%), Gaps = 10/133 (7%)
Query: 509 DVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRV-CPHAC 565
DVDEC EG +C C NT S++C C GY DG HC+D+DEC +E C H C
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDNAGCVHDC 86
Query: 566 ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
N+ G+Y C C +G+ D N C D++EC E C C+N GS+ C C G
Sbjct: 87 VNIPGNYRCTCYDGFHLA---HDGHN-CLDVDECAEGNGGCQQS-CVNMMGSYECHCREG 141
Query: 626 FEPSEDGTDCIDR 638
F S++ CI R
Sbjct: 142 FFLSDNQHTCIQR 154
Score = 100 bits (240), Expect = 2e-20
Identities = 49/114 (42%), Positives = 58/114 (50%), Gaps = 9/114 (7%)
Query: 747 DVDECAA------IPGLC--APGRFRCVCGPGYRPAGEVCADVDECAVRPPP-CDQLCHN 797
DVDEC I +C P ++C+C GY G+ C DVDEC C C N
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHDCVN 88
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G+Y C C G+ L DG NC DVDEC CQQ C N GSYEC C +G+
Sbjct: 89 IPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGF 142
Score = 98.7 bits (235), Expect = 8e-20
Identities = 40/89 (44%), Positives = 55/89 (61%), Gaps = 3/89 (3%)
Query: 765 CVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDV 822
C C G+ +P + C D+DEC + CD +C NT GS++C C+ GY+L + NC+D+
Sbjct: 260 CTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDI 319
Query: 823 DECERDTHTCQQICSNTEGSYECSCEDGY 851
DEC D TC IC NT GS++C C GY
Sbjct: 320 DECSFD-RTCDHICVNTPGSFQCLCHRGY 347
Score = 86.2 bits (204), Expect = 4e-16
Identities = 46/112 (41%), Positives = 57/112 (50%), Gaps = 10/112 (8%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNT 798
D+DEC G C G F C C GY+ C D+DEC+ CD +C NT
Sbjct: 277 DIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSF-DRTCDHICVNT 335
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
GS+ CLC GY L +C DVDEC + C+ C NT GSY+C+C G
Sbjct: 336 PGSFQCLCHRGYLL-YGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAG 386
Score = 81.4 bits (192), Expect = 1e-14
Identities = 42/106 (39%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 754 IPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYE 811
+PGLC Y A + DVDEC C D +C NT SY C+C++GY
Sbjct: 6 VPGLCLLVLLVHARAAQYSKAAQ---DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT 62
Query: 812 LDEDGANCRDVDECERDTHT-CQQICSNTEGSYECSCEDGYEKRGD 856
DG +C+DVDECER+ + C C N G+Y C+C DG+ D
Sbjct: 63 --GDGKHCKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHD 106
Score = 80.6 bits (190), Expect = 2e-14
Identities = 32/78 (41%), Positives = 43/78 (55%), Gaps = 2/78 (2%)
Query: 775 GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ 834
G+ C ++ CAV CD CH+ C C G+ L D C+D+DEC + C
Sbjct: 233 GKTC--IETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDH 290
Query: 835 ICSNTEGSYECSCEDGYE 852
IC NT GS+ECSC+ GY+
Sbjct: 291 ICRNTVGSFECSCKKGYK 308
Score = 79.8 bits (188), Expect = 4e-14
Identities = 47/120 (39%), Positives = 55/120 (45%), Gaps = 14/120 (11%)
Query: 747 DVDEC-----AAIPGLCA--PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
DVDEC A C PG +RC C G+ A G C DVDECA C Q C N
Sbjct: 70 DVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVN 129
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDE----CERDTHTCQQICSNT-EGSYECSCEDGYE 852
GSY+C CR G+ L ++ C E C H C IC T +G C C G+E
Sbjct: 130 MMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFE 189
Score = 43.2 bits (97), Expect = 0.004
Identities = 19/41 (46%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Query: 820 RDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDAC 858
+DVDEC T C IC NT SY+C C+ GY G C
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHC 68
Score = 41.5 bits (93), Expect = 0.012
Identities = 25/106 (23%), Positives = 36/106 (33%), Gaps = 2/106 (1%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
CA I G C C PG+ C C C +T+ C C +
Sbjct: 168 CAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKF 227
Query: 811 ELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
L DG C ++ C + C C + C+C G+ + D
Sbjct: 228 VLHTDGKTC--IETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPD 271
Score = 37.5 bits (83), Expect = 0.20
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 592 ACEDINECEEQEDLCS-GGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
A +D++EC E D C +C NT S+ C C +G+ + DG C D
Sbjct: 26 AAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKD 70
>BC052263-1|AAH52263.2| 992|Homo sapiens signal peptide, CUB
domain, EGF-like 3 protein.
Length = 992
Score = 206 bits (502), Expect = 3e-52
Identities = 138/415 (33%), Positives = 186/415 (44%), Gaps = 54/415 (13%)
Query: 232 DVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHP-CGRDG 289
DV+EC EG C + C+NT S++C C GYT DG++C+DVDEC+ + C D
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDNAGCVHD- 85
Query: 290 NPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
C N G Y C+C G+ L G C+D DEC E C C N G Y C C G
Sbjct: 86 ---CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREG 141
Query: 348 WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS 407
+ C+ + + G H C E G CE
Sbjct: 142 FFLSDNQHTCIQRPEGMNCMNKNHGCAH------------ICRETPKGGIACE------- 182
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGG---RCVNTDGSFRCECPDGYVLAPDGL 464
C+ G LT++ +C++ + GG C +T+ RC C +VL DG
Sbjct: 183 ------CRPGF---ELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGK 233
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCTFR 523
+C++ CA++ C + C + G C C GF PD+ TC D+DEC C
Sbjct: 234 TCIET--CAVNNGGC-DSKCHDAAIGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHI 290
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRT 583
C NT GSF C+C GY + + +C+DIDEC + R C H C N GS+ C C GY
Sbjct: 291 CRNTVGSFECSCKKGYKLLINERNCQDIDECSFD-RTCDHICVNTPGSFQCLCHRGYLLY 349
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSE-DGTDCID 637
C D++EC C G CINT GS+ C C AG +G DC +
Sbjct: 350 GITH-----CGDVDECSINRGGCRFG-CINTPGSYQCTCPAGQGRLHWNGKDCTE 398
Score = 197 bits (481), Expect = 1e-49
Identities = 135/389 (34%), Positives = 174/389 (44%), Gaps = 30/389 (7%)
Query: 190 RDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNEC-REGGMVCRNGR 247
+DVDEC C + C+N P +Y C C G+ G C DV+EC RE C +
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY-TGDGKHCKDVDECEREDNAGCVHD- 85
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
C N G++RC C G+ L DG NC DVDEC E C + SC N G YEC C G
Sbjct: 86 CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQ----SCVNMMGSYECHCREG 141
Query: 308 WKLVGRR--CVDRDE---CKELPYVCAGGECRNF-NGGYVCECPAGWRFDKTAAVCV--- 358
+ L + C+ R E C + CA CR GG CEC G+ K C
Sbjct: 142 FFLSDNQHTCIQRPEGMNCMNKNHGCAH-ICRETPKGGIACECRPGFELTKNQRDCKLTC 200
Query: 359 ----DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRY-CE-RCPAPDSAEFMR 412
+ C D + RC L C E A C+ +C
Sbjct: 201 NYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAAIGVHCT 260
Query: 413 ICQGGMGRPN--LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDAD 470
G M +P+ +D+DECR+ C C NT GSF C C GY L + +C D D
Sbjct: 261 CPVGFMLQPDRKTCKDIDECRLNNGGC-DHICRNTVGSFECSCKKGYKLLINERNCQDID 319
Query: 471 ECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGS 530
EC+ D R C + C NT G ++C C G+ C DVDEC+ R C F C NT GS
Sbjct: 320 ECSFD-RTCDH-ICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTPGS 377
Query: 531 FRCTCPYGYA-VAADGVHCRDIDECVQEP 558
++CTCP G + +G C + +C P
Sbjct: 378 YQCTCPAGQGRLHWNGKDCTEPLKCQGSP 406
Score = 161 bits (392), Expect = 7e-39
Identities = 128/421 (30%), Positives = 181/421 (42%), Gaps = 47/421 (11%)
Query: 104 SHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC--GDQRI 161
S +DVDEC G C A C N P +++C C GY T C+DVDEC D
Sbjct: 24 SKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDECEREDNAG 81
Query: 162 CDHGDCRNTIGSYRCECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCD 219
C H DC N G+YRC C G+ L + C DVDEC+ C+ +C N+ G+Y CHC
Sbjct: 82 CVH-DCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQ-SCVNMMGSYECHCR 139
Query: 220 DGFKAGPN-NDCVDVNECREGGMVCRNGR------CRNT-VGSFRCECAPGYTLTADGRN 271
+GF N + C+ R GM C N CR T G CEC PG+ LT + R+
Sbjct: 140 EGFFLSDNQHTCIQ----RPEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRD 195
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCA 329
C+ C+ C +C +T G C C + L G+ C+ + C C
Sbjct: 196 CKLT--CNYGNGGC----QHTCDDTEQGPRCGCHIKFVLHTDGKTCI--ETCAVNNGGC- 246
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVC--VDERK-------ELCYDEWEAGRCHRARPL 380
+C + G C CP G+ C +DE + +C + + C +
Sbjct: 247 DSKCHDAAIGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGY 306
Query: 381 QLARPECCCS--EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ--DLDECRVRPDV 436
+L E C + ++ R C+ F +C G +T D+DEC +
Sbjct: 307 KLLINERNCQDIDECSFDRTCDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGG 366
Query: 437 CVGGRCVNTDGSFRCECPDGY-VLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQC 495
C G C+NT GS++C CP G L +G C + +C P S R G + C
Sbjct: 367 CRFG-CINTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQGSPG-ASKAMLSCNRSGKKDTC 424
Query: 496 S 496
+
Sbjct: 425 A 425
Score = 139 bits (337), Expect = 3e-32
Identities = 92/284 (32%), Positives = 124/284 (43%), Gaps = 15/284 (5%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ-C 126
+DEC C+ +C + ++C C G+ + H C E G A C
Sbjct: 113 VDECAEGNGGCQQ-SCVNMMGSYECHCREGFFLSDNQHTCIQRPEGMNCMNKNHGCAHIC 171
Query: 127 VNLP-GAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
P G C C PG+ LT + +C+ G+ C H C +T RC C + L
Sbjct: 172 RETPKGGIACECRPGFELTKNQRDCKLTCNYGNGG-CQH-TCDDTEQGPRCGCHIKFVLH 229
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCR 244
+ ++ C+ C + C + C C GF P+ C D++ECR C
Sbjct: 230 TDGKTCIETCAVNNGGC-DSKCHDAAIGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCD 288
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
+ CRNTVGSF C C GY L + RNC+D+DEC R + C NT G ++C C
Sbjct: 289 H-ICRNTVGSFECSCKKGYKLLINERNCQDIDECS-----FDRTCDHICVNTPGSFQCLC 342
Query: 305 GAGWKLVG-RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
G+ L G C D DEC C G C N G Y C CPAG
Sbjct: 343 HRGYLLYGITHCGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 385
Score = 107 bits (258), Expect = 1e-22
Identities = 55/136 (40%), Positives = 71/136 (52%), Gaps = 10/136 (7%)
Query: 509 DVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRV-CPHAC 565
DVDEC EG +C C NT S++C C GY DG HC+D+DEC +E C H C
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDNAGCVHDC 86
Query: 566 ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
N+ G+Y C C +G+ D N C D++EC E C C+N GS+ C C G
Sbjct: 87 VNIPGNYRCTCYDGFHLA---HDGHN-CLDVDECAEGNGGCQQS-CVNMMGSYECHCREG 141
Query: 626 FEPSEDGTDCIDRRTG 641
F S++ CI R G
Sbjct: 142 FFLSDNQHTCIQRPEG 157
Score = 100 bits (240), Expect = 2e-20
Identities = 49/114 (42%), Positives = 58/114 (50%), Gaps = 9/114 (7%)
Query: 747 DVDECAA------IPGLC--APGRFRCVCGPGYRPAGEVCADVDECAVRPPP-CDQLCHN 797
DVDEC I +C P ++C+C GY G+ C DVDEC C C N
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHDCVN 88
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G+Y C C G+ L DG NC DVDEC CQQ C N GSYEC C +G+
Sbjct: 89 IPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGF 142
Score = 98.7 bits (235), Expect = 8e-20
Identities = 40/89 (44%), Positives = 55/89 (61%), Gaps = 3/89 (3%)
Query: 765 CVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDV 822
C C G+ +P + C D+DEC + CD +C NT GS++C C+ GY+L + NC+D+
Sbjct: 259 CTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDI 318
Query: 823 DECERDTHTCQQICSNTEGSYECSCEDGY 851
DEC D TC IC NT GS++C C GY
Sbjct: 319 DECSFD-RTCDHICVNTPGSFQCLCHRGY 346
Score = 86.2 bits (204), Expect = 4e-16
Identities = 46/112 (41%), Positives = 57/112 (50%), Gaps = 10/112 (8%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNT 798
D+DEC G C G F C C GY+ C D+DEC+ CD +C NT
Sbjct: 276 DIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSF-DRTCDHICVNT 334
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
GS+ CLC GY L +C DVDEC + C+ C NT GSY+C+C G
Sbjct: 335 PGSFQCLCHRGYLL-YGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAG 385
Score = 81.4 bits (192), Expect = 1e-14
Identities = 42/106 (39%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 754 IPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYE 811
+PGLC Y A + DVDEC C D +C NT SY C+C++GY
Sbjct: 6 VPGLCLLVLLVHARAAQYSKAAQ---DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT 62
Query: 812 LDEDGANCRDVDECERDTHT-CQQICSNTEGSYECSCEDGYEKRGD 856
DG +C+DVDECER+ + C C N G+Y C+C DG+ D
Sbjct: 63 --GDGKHCKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHD 106
Score = 80.6 bits (190), Expect = 2e-14
Identities = 47/119 (39%), Positives = 55/119 (46%), Gaps = 13/119 (10%)
Query: 747 DVDEC-----AAIPGLCA--PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
DVDEC A C PG +RC C G+ A G C DVDECA C Q C N
Sbjct: 70 DVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVN 129
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDE---CERDTHTCQQICSNT-EGSYECSCEDGYE 852
GSY+C CR G+ L ++ C E C H C IC T +G C C G+E
Sbjct: 130 MMGSYECHCREGFFLSDNQHTCIQRPEGMNCMNKNHGCAHICRETPKGGIACECRPGFE 188
Score = 79.8 bits (188), Expect = 4e-14
Identities = 32/78 (41%), Positives = 43/78 (55%), Gaps = 2/78 (2%)
Query: 775 GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ 834
G+ C ++ CAV CD CH+ C C G+ L D C+D+DEC + C
Sbjct: 232 GKTC--IETCAVNNGGCDSKCHDAAIGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDH 289
Query: 835 ICSNTEGSYECSCEDGYE 852
IC NT GS+ECSC+ GY+
Sbjct: 290 ICRNTVGSFECSCKKGYK 307
Score = 43.2 bits (97), Expect = 0.004
Identities = 19/41 (46%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Query: 820 RDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDAC 858
+DVDEC T C IC NT SY+C C+ GY G C
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHC 68
Score = 40.7 bits (91), Expect = 0.022
Identities = 25/106 (23%), Positives = 36/106 (33%), Gaps = 2/106 (1%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
CA I G C C PG+ C C C +T+ C C +
Sbjct: 167 CAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKF 226
Query: 811 ELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
L DG C ++ C + C C + C+C G+ + D
Sbjct: 227 VLHTDGKTC--IETCAVNNGGCDSKCHDAAIGVHCTCPVGFMLQPD 270
Score = 37.5 bits (83), Expect = 0.20
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 592 ACEDINECEEQEDLCS-GGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
A +D++EC E D C +C NT S+ C C +G+ + DG C D
Sbjct: 26 AAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKD 70
>U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jagged
protein.
Length = 1214
Score = 202 bits (494), Expect = 3e-51
Identities = 174/649 (26%), Positives = 271/649 (41%), Gaps = 88/649 (13%)
Query: 8 QSCAGAVGVPQTKYLCCCSVGHAW-GAPCEACPPRGSPAHTALCGEKPGEYINPVTNE-- 64
Q C+ G + C C G W G C+ C P H +C E P + + TN
Sbjct: 223 QGCSPKHGSCKLPGDCRCQYG--WQGLYCDKCIPHPGCVH-GICNE-PWQCLCE-TNWGG 277
Query: 65 ---TKPIDECDIMPQLCKPGTCHDT-PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
K ++ C GTC +T P +QC C GY N C ++ E + PC
Sbjct: 278 QLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPN----C-EIAEHACLSDPC 332
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
C FEC C PG+ P+ ++D+C G C++ + ++C C P
Sbjct: 333 HNRGSCKETSLGFECECSPGWT-GPTCST--NIDDCSPNNCSHGGTCQDLVNGFKCVCPP 389
Query: 181 GYTLRENVCR-DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREG 239
+T + C+ D +EC +P +C+NL +Y C C G+ G N D +++N+C
Sbjct: 390 QWTGK--TCQLDANECEA-KPCVNAKSCKNLIASYYCDCLPGWM-GQNCD-ININDCL-- 442
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNG 298
G + CR+ V +RC C PGY G +C RD+DEC +PC G+ C N
Sbjct: 443 GQCQNDASCRDLVNGYRCICPPGYA----GDHCERDIDECAS--NPCLNGGH--CQNEIN 494
Query: 299 GYECSCGAGWKLVGRRC-VDRDECKELPYVCAGG-ECRNFNGGYVCECPAGWRFDKTAAV 356
++C C G+ G C +D D C+ P C G +C N Y C+CP + + +
Sbjct: 495 RFQCLCPTGFS--GNLCQLDIDYCEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHL 550
Query: 357 CVDERKELC--YDEWEAGRCHRARP--LQLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
R C D P ++ C G +C + +F
Sbjct: 551 KDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHG--------KCKSQSGGKFTC 602
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDAD 470
C G +++++C P C GG C++ S++C C DG+ +G C + +
Sbjct: 603 DCNKGFTGTYCHENINDCESNP--CRNGGTCIDGVNSYKCICSDGW----EGAYCETNIN 656
Query: 471 ECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVD-ECAEGRASCTFRCHNTA 528
+C+ +P C NG TC + + C C G+ +TC D +C E + C++
Sbjct: 657 DCSQNP--CHNGGTCRDLVNDFYCDCKNGWK---GKTCHSRDSQCDEATCNNGGTCYDEG 711
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG--SYICKCPEGYRRTSAP 586
+F+C CP G+ +G C P C + VV S+ C C EG+
Sbjct: 712 DAFKCMCPGGW----EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICA 767
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
Q++ N+C + G C++ D + C+C GF G DC
Sbjct: 768 QNT-------NDCSPHP-CYNSGTCVDGDNWYRCECAPGFA----GPDC 804
Score = 170 bits (414), Expect = 2e-41
Identities = 164/607 (27%), Positives = 253/607 (41%), Gaps = 84/607 (13%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCV 127
D+C P C G C++ +QC C+ + LC +D++ C +P C C
Sbjct: 250 DKCIPHPG-CVHGICNEP---WQCLCETNWG----GQLCDKDLNYCGTHQP-CLNGGTCS 300
Query: 128 NL-PGAFECRCPPGYRLTPSLDECEDVDE-CGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
N P ++C CP GY S CE + C + G C+ T + CEC PG+T
Sbjct: 301 NTGPDKYQCSCPEGY----SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWT-G 355
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVCR 244
++D+CS P GTC++L + C C + C +D NEC C
Sbjct: 356 PTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCPPQW---TGKTCQLDANECE--AKPCV 409
Query: 245 NGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS 303
N + C+N + S+ C+C PG+ G+NC D++ D L C D SC + GY C
Sbjct: 410 NAKSCKNLIASYYCDCLPGWM----GQNC-DININDCLGQ-CQNDA--SCRDLVNGYRCI 461
Query: 304 CGAGWKLVGRRCV-DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
C G+ G C D DEC P + GG C+N + C CP G+ + +C
Sbjct: 462 CPPGY--AGDHCERDIDECASNPCL-NGGHCQNEINRFQCLCPTGF----SGNLC----- 509
Query: 363 ELCYDEWEAGRCHRARPLQLARPE--CCCSEGAAWGRYC----ERCPAPDSAEFMRICQG 416
+L D E C + C C E G+ C + C E + C
Sbjct: 510 QLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE-GKNCSHLKDHC-RTTPCEVIDSCTV 567
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVN-TDGSFRCECPDGYVLAPDGLSC-VDADECA 473
M + + + + +VC G+C + + G F C+C G+ G C + ++C
Sbjct: 568 AMASNDTPEGVR--YISSNVCGPHGKCKSQSGGKFTCDCNKGFT----GTYCHENINDCE 621
Query: 474 LDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
+P C N GTC + Y+C CS G+ +T ++++C++ C + F
Sbjct: 622 SNP--CRNGGTCIDGVNSYKCICSDGWEGAYCET--NINDCSQNPCHNGGTCRDLVNDFY 677
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
C C G+ H RD +C + C + ++ C CP G+ T+ ++
Sbjct: 678 CDCKNGW--KGKTCHSRD-SQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSS 734
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP---SEDGTDCIDR---RTGTCYRS 646
C N C +GG C+ SF C C G+E +++ DC +GTC
Sbjct: 735 CLP-NPCH------NGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDG 787
Query: 647 LVSGRCE 653
RCE
Sbjct: 788 DNWYRCE 794
Score = 164 bits (399), Expect = 1e-39
Identities = 175/639 (27%), Positives = 262/639 (41%), Gaps = 115/639 (17%)
Query: 20 KYLCCCSVGHAWGAPCEA---------CPPRGSPAHTAL---CGEKPGEYINPVTNETKP 67
KY C C G++ G CE C RGS T+L C PG + P +
Sbjct: 306 KYQCSCPEGYS-GPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPG-WTGPTCSTN-- 361
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQ 125
ID+C P C G TC D GF+C C + T C+ D +EC PC
Sbjct: 362 IDDCS--PNNCSHGGTCQDLVNGFKCVCPPQW----TGKTCQLDANECE--AKPCVNAKS 413
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
C NL ++ C C PG+ C+ ++++C Q D CR+ + YRC C PGY
Sbjct: 414 CKNLIASYYCDCLPGWMG----QNCDININDCLGQCQND-ASCRDLVNGYRCICPPGYA- 467
Query: 185 RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVC 243
++ RD+DEC+ P G C+N + C C GF N C +D++ C C
Sbjct: 468 GDHCERDIDECAS-NPCLNGGHCQNEINRFQCLCPTGFSG---NLCQLDIDYCEPNP--C 521
Query: 244 RNG-RCRNTVGSFRCECAPGYTLTADGRNCRDV-DECDELPHPCGRDGNPSCTNTNGGYE 301
+NG +C N + C+C Y +G+NC + D C P C + SCT +
Sbjct: 522 QNGAQCYNRASDYFCKCPEDY----EGKNCSHLKDHCRTTP--C--EVIDSCTVAMASND 573
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGG-YVCECPAGWRFDKTAAVCVDE 360
G R + + C P+ G+C++ +GG + C+C G+ T C +
Sbjct: 574 TPEGV-------RYISSNVCG--PH----GKCKSQSGGKFTCDCNKGF----TGTYCHEN 616
Query: 361 RKELCYDEWEAGRCHRARPL--QLARPECCCSEGAAW-GRYCERCPAPDSAEFMRICQGG 417
++ E+ C + +C CS+G W G YCE D ++ C G
Sbjct: 617 -----INDCESNPCRNGGTCIDGVNSYKCICSDG--WEGAYCET-NINDCSQ--NPCHNG 666
Query: 418 MGRPNLTQDL----------DECRVRPDVCV------GGRCVNTDGSFRCECPDGYVLAP 461
+L D C R C GG C + +F+C CP G+
Sbjct: 667 GTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW---- 722
Query: 462 DGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRAS 519
+G +C A + P C NG TC + C C G+ +GP C + ++C+
Sbjct: 723 EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGW-EGP--ICAQNTNDCSPHPCY 779
Query: 520 CTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPE 578
+ C + +RC C G+A G CR +I+EC P C + + Y C CP
Sbjct: 780 NSGTCVDGDNWYRCECAPGFA----GPDCRININECQSSPCAFGATCVDEINGYRCVCPP 835
Query: 579 GYRRTSAPQDSENAC----EDINECEEQEDLCSGGVCIN 613
G+ + S C I + + +D C+ C+N
Sbjct: 836 GHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLN 874
Score = 163 bits (396), Expect = 2e-39
Identities = 158/579 (27%), Positives = 242/579 (41%), Gaps = 112/579 (19%)
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIG 172
C G P G + LPG +CRC G++ C D+C C HG C
Sbjct: 221 CRQGCSPKHGSCK---LPG--DCRCQYGWQGL----YC---DKCIPHPGCVHGICNEP-- 266
Query: 173 SYRCECKPGYTLRENVC-RDVDECSRPRPVCRNGTCENL-PGAYLCHCDDGFKAGPNNDC 230
++C C+ + +C +D++ C +P GTC N P Y C C +G+ +GPN +
Sbjct: 267 -WQCLCETNWG--GQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY-SGPNCEI 322
Query: 231 VDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRD 288
+ + C C N G C+ T F CEC+PG+T G C ++D+C P+ C
Sbjct: 323 AE-HACLSDP--CHNRGSCKETSLGFECECSPGWT----GPTCSTNIDDCS--PNNCSHG 373
Query: 289 GNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
G +C + G++C C W G+ C +D +EC+ P V A C+N Y C+C G
Sbjct: 374 G--TCQDLVNGFKCVCPPQW--TGKTCQLDANECEAKPCVNA-KSCKNLIASYYCDCLPG 428
Query: 348 W---RFDKTAAVCVD--ERKELCYDEWEAGRCHRARPLQLARPEC------CCSEGAAWG 396
W D C+ + C D RC P A C C S G
Sbjct: 429 WMGQNCDININDCLGQCQNDASCRDLVNGYRC--ICPPGYAGDHCERDIDECASNPCLNG 486
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQ-DLDECRVRPDVCV-GGRCVNTDGSFRCECP 454
+C+ + F +C G NL Q D+D C P+ C G +C N + C+CP
Sbjct: 487 GHCQN----EINRFQCLCPTGFS-GNLCQLDIDYC--EPNPCQNGAQCYNRASDYFCKCP 539
Query: 455 DGYVLAPDGLSCVD-ADECALDP-------------------------RICG-NGTCSNT 487
+ Y +G +C D C P +CG +G C +
Sbjct: 540 EDY----EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQ 595
Query: 488 RGG-YECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGV 546
GG + C C+ GFT ++++C C + S++C C G+ +G
Sbjct: 596 SGGKFTCDCNKGFT--GTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGW----EGA 649
Query: 547 HCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYR-RTSAPQDSENACEDINECEEQED 604
+C +I++C Q P C ++V + C C G++ +T +DS+ C++ C
Sbjct: 650 YCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ--CDEAT-CN---- 702
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
+GG C + +F C C G+E GT C R +C
Sbjct: 703 --NGGTCYDEGDAFKCMCPGGWE----GTTCNIARNSSC 735
Score = 120 bits (290), Expect = 2e-26
Identities = 90/320 (28%), Positives = 134/320 (41%), Gaps = 47/320 (14%)
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARP---------ECCCSEGAAW-GRYCERC-PAP 405
C + C + W C+RA Q P +C C G W G YC++C P P
Sbjct: 199 CDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYG--WQGLYCDKCIPHP 256
Query: 406 DSAE------FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTD-GSFRCECPDGYV 458
+ +C+ G +DL+ C GG C NT ++C CP+GY
Sbjct: 257 GCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY- 315
Query: 459 LAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGR 517
G +C A+ L G+C T G+EC+CSPG+T GP TC ++D+C+
Sbjct: 316 ---SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWT-GP--TCSTNIDDCSPNN 369
Query: 518 ASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKC 576
S C + F+C CP + G C+ D +EC +P V +C+N++ SY C C
Sbjct: 370 CSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKSCKNLIASYYCDC 425
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLCDCDAGFEPSEDGTDC 635
G+ +N +IN+C Q C C + + C C G+ D
Sbjct: 426 LPGWM-------GQNCDININDCLGQ---CQNDASCRDLVNGYRCICPPGYAGDHCERDI 475
Query: 636 IDRRTGTCYRSLVSGRCEPE 655
+ + C L G C+ E
Sbjct: 476 DECASNPC---LNGGHCQNE 492
Score = 64.5 bits (150), Expect = 2e-09
Identities = 35/92 (38%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
+RC+C PGY AG+ C D+DECA P C N + CLC TG+ G C+
Sbjct: 458 YRCICPPGY--AGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGF----SGNLCQL 511
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
D+D CE + C N Y C C + YE
Sbjct: 512 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE 543
Score = 56.8 bits (131), Expect = 3e-07
Identities = 55/215 (25%), Positives = 89/215 (41%), Gaps = 36/215 (16%)
Query: 74 MPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNLPG 131
+P C GTC F C C G+E +C ++ ++CS PC CV+
Sbjct: 736 LPNPCHNGGTCVVNGESFTCVCKEGWE----GPICAQNTNDCS--PHPCYNSGTCVDGDN 789
Query: 132 AFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR 190
+ C C PG+ + +C +++EC C + I YRC C PG++ + C+
Sbjct: 790 WYRCECAPGF----AGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAK--CQ 843
Query: 191 DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRN 250
+V RP G+ +P DG K ++DC + +C G + C C
Sbjct: 844 EVS----GRPCITMGSV--IP--------DGAKW--DDDC-NTCQCLNGRIACSKVWC-- 884
Query: 251 TVGSFRCECAPGYTLTADGRNCRDVDECDELPHPC 285
G C G++ G++C + + HPC
Sbjct: 885 --GPRPCLLHKGHSECPSGQSCIPILDDQCFVHPC 917
Score = 46.8 bits (106), Expect = 3e-04
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 761 GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G+F C C G+ G C + +++C P C + SY C+C G+E GA C
Sbjct: 598 GKFTCDCNKGF--TGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWE----GAYC 651
Query: 820 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
++++C ++ C + + C C++G+ +G C
Sbjct: 652 ETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGW--KGKTC 689
Score = 46.4 bits (105), Expect = 4e-04
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F CVC G+ G +CA + ++C+ P C + D Y C C G+ G +CR
Sbjct: 753 FTCVCKEGWE--GPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFA----GPDCRI 806
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
+++EC+ C + Y C C G+
Sbjct: 807 NINECQSSPCAFGATCVDEINGYRCVCPPGH 837
Score = 45.2 bits (102), Expect = 0.001
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F C C PG+ G C+ ++D+C+ C + + C+C + G C+
Sbjct: 345 FECECSPGW--TGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQL 398
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
D +ECE + C N SY C C G+
Sbjct: 399 DANECEAKPCVNAKSCKNLIASYYCDCLPGW 429
Score = 45.2 bits (102), Expect = 0.001
Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 17/120 (14%)
Query: 747 DVDECAAIPGLCAPG------RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D +EC A P + A + C C PG+ G+ C ++++C + D C +
Sbjct: 399 DANECEAKPCVNAKSCKNLIASYYCDCLPGWM--GQNCDININDCLGQCQN-DASCRDLV 455
Query: 800 GSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
Y C+C GY G +C RD+DEC + C N ++C C G+ G+ C
Sbjct: 456 NGYRCICPPGYA----GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFS--GNLC 509
Score = 45.2 bits (102), Expect = 0.001
Identities = 28/120 (23%), Positives = 54/120 (45%), Gaps = 16/120 (13%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
++++C + P G C G ++C+C G+ G C ++++C+ P C +
Sbjct: 616 NINDCESNPCRNGGTCIDGVNSYKCICSDGWE--GAYCETNINDCSQNPCHNGGTCRDLV 673
Query: 800 GSYDCLCRTGYELDEDGANCRDVD-ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
+ C C+ G++ G C D +C+ T C + +++C C G+E G C
Sbjct: 674 NDFYCDCKNGWK----GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE--GTTC 727
Score = 39.5 bits (88), Expect = 0.050
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 13/94 (13%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC- 819
F+C+C G+ G C + P PC C S+ C+C+ G+E G C
Sbjct: 714 FKCMCPGGWE--GTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE----GPICA 767
Query: 820 RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
++ ++C H C C + + Y C C G+
Sbjct: 768 QNTNDC--SPHPCYNSGTCVDGDNWYRCECAPGF 799
Score = 39.5 bits (88), Expect = 0.050
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 9/70 (12%)
Query: 756 GLCAPGR--FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G C G +RC C PG+ AG C +++EC P C + Y C+C G+
Sbjct: 782 GTCVDGDNWYRCECAPGF--AGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGH-- 837
Query: 813 DEDGANCRDV 822
GA C++V
Sbjct: 838 --SGAKCQEV 845
Score = 35.5 bits (78), Expect = 0.81
Identities = 35/107 (32%), Positives = 46/107 (42%), Gaps = 22/107 (20%)
Query: 751 CAAIPGLCA-PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C+ G C PG RC Y G C D+C P +C+ + CLC T
Sbjct: 225 CSPKHGSCKLPGDCRCQ----YGWQGLYC---DKCIPHPGCVHGICNEP---WQCLCETN 274
Query: 810 YELDEDGANC-RDVDECERDTHT-CQQ--ICSNT-EGSYECSCEDGY 851
+ G C +D++ C TH C CSNT Y+CSC +GY
Sbjct: 275 W----GGQLCDKDLNYC--GTHQPCLNGGTCSNTGPDKYQCSCPEGY 315
>U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein.
Length = 1218
Score = 202 bits (494), Expect = 3e-51
Identities = 174/649 (26%), Positives = 271/649 (41%), Gaps = 88/649 (13%)
Query: 8 QSCAGAVGVPQTKYLCCCSVGHAW-GAPCEACPPRGSPAHTALCGEKPGEYINPVTNE-- 64
Q C+ G + C C G W G C+ C P H +C E P + + TN
Sbjct: 236 QGCSPKHGSCKLPGDCRCQYG--WQGLYCDKCIPHPGCVH-GICNE-PWQCLCE-TNWGG 290
Query: 65 ---TKPIDECDIMPQLCKPGTCHDT-PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
K ++ C GTC +T P +QC C GY N C ++ E + PC
Sbjct: 291 QLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPN----C-EIAEHACLSDPC 345
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
C FEC C PG+ P+ ++D+C G C++ + ++C C P
Sbjct: 346 HNRGSCKETSLGFECECSPGWT-GPTCST--NIDDCSPNNCSHGGTCQDLVNGFKCVCPP 402
Query: 181 GYTLRENVCR-DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREG 239
+T + C+ D +EC +P +C+NL +Y C C G+ G N D +++N+C
Sbjct: 403 QWTGK--TCQLDANECEA-KPCVNAKSCKNLIASYYCDCLPGWM-GQNCD-ININDCL-- 455
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNG 298
G + CR+ V +RC C PGY G +C RD+DEC +PC G+ C N
Sbjct: 456 GQCQNDASCRDLVNGYRCICPPGYA----GDHCERDIDECAS--NPCLNGGH--CQNEIN 507
Query: 299 GYECSCGAGWKLVGRRC-VDRDECKELPYVCAGG-ECRNFNGGYVCECPAGWRFDKTAAV 356
++C C G+ G C +D D C+ P C G +C N Y C+CP + + +
Sbjct: 508 RFQCLCPTGFS--GNLCQLDIDYCEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHL 563
Query: 357 CVDERKELC--YDEWEAGRCHRARP--LQLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
R C D P ++ C G +C + +F
Sbjct: 564 KDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHG--------KCKSQSGGKFTC 615
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDAD 470
C G +++++C P C GG C++ S++C C DG+ +G C + +
Sbjct: 616 DCNKGFTGTYCHENINDCESNP--CRNGGTCIDGVNSYKCICSDGW----EGAYCETNIN 669
Query: 471 ECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVD-ECAEGRASCTFRCHNTA 528
+C+ +P C NG TC + + C C G+ +TC D +C E + C++
Sbjct: 670 DCSQNP--CHNGGTCRDLVNDFYCDCKNGWK---GKTCHSRDSQCDEATCNNGGTCYDEG 724
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG--SYICKCPEGYRRTSAP 586
+F+C CP G+ +G C P C + VV S+ C C EG+
Sbjct: 725 DAFKCMCPGGW----EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICA 780
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
Q++ N+C + G C++ D + C+C GF G DC
Sbjct: 781 QNT-------NDCSPHP-CYNSGTCVDGDNWYRCECAPGFA----GPDC 817
Score = 170 bits (414), Expect = 2e-41
Identities = 164/607 (27%), Positives = 253/607 (41%), Gaps = 84/607 (13%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCV 127
D+C P C G C++ +QC C+ + LC +D++ C +P C C
Sbjct: 263 DKCIPHPG-CVHGICNEP---WQCLCETNWG----GQLCDKDLNYCGTHQP-CLNGGTCS 313
Query: 128 NL-PGAFECRCPPGYRLTPSLDECEDVDE-CGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
N P ++C CP GY S CE + C + G C+ T + CEC PG+T
Sbjct: 314 NTGPDKYQCSCPEGY----SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWT-G 368
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVCR 244
++D+CS P GTC++L + C C + C +D NEC C
Sbjct: 369 PTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCPPQW---TGKTCQLDANECE--AKPCV 422
Query: 245 NGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS 303
N + C+N + S+ C+C PG+ G+NC D++ D L C D SC + GY C
Sbjct: 423 NAKSCKNLIASYYCDCLPGWM----GQNC-DININDCLGQ-CQNDA--SCRDLVNGYRCI 474
Query: 304 CGAGWKLVGRRCV-DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
C G+ G C D DEC P + GG C+N + C CP G+ + +C
Sbjct: 475 CPPGY--AGDHCERDIDECASNPCL-NGGHCQNEINRFQCLCPTGF----SGNLC----- 522
Query: 363 ELCYDEWEAGRCHRARPLQLARPE--CCCSEGAAWGRYC----ERCPAPDSAEFMRICQG 416
+L D E C + C C E G+ C + C E + C
Sbjct: 523 QLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE-GKNCSHLKDHC-RTTPCEVIDSCTV 580
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVN-TDGSFRCECPDGYVLAPDGLSC-VDADECA 473
M + + + + +VC G+C + + G F C+C G+ G C + ++C
Sbjct: 581 AMASNDTPEGVR--YISSNVCGPHGKCKSQSGGKFTCDCNKGFT----GTYCHENINDCE 634
Query: 474 LDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
+P C N GTC + Y+C CS G+ +T ++++C++ C + F
Sbjct: 635 SNP--CRNGGTCIDGVNSYKCICSDGWEGAYCET--NINDCSQNPCHNGGTCRDLVNDFY 690
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
C C G+ H RD +C + C + ++ C CP G+ T+ ++
Sbjct: 691 CDCKNGW--KGKTCHSRD-SQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSS 747
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP---SEDGTDCIDR---RTGTCYRS 646
C N C +GG C+ SF C C G+E +++ DC +GTC
Sbjct: 748 CLP-NPCH------NGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDG 800
Query: 647 LVSGRCE 653
RCE
Sbjct: 801 DNWYRCE 807
Score = 164 bits (399), Expect = 1e-39
Identities = 175/639 (27%), Positives = 262/639 (41%), Gaps = 115/639 (17%)
Query: 20 KYLCCCSVGHAWGAPCEA---------CPPRGSPAHTAL---CGEKPGEYINPVTNETKP 67
KY C C G++ G CE C RGS T+L C PG + P +
Sbjct: 319 KYQCSCPEGYS-GPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPG-WTGPTCSTN-- 374
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQ 125
ID+C P C G TC D GF+C C + T C+ D +EC PC
Sbjct: 375 IDDCS--PNNCSHGGTCQDLVNGFKCVCPPQW----TGKTCQLDANECE--AKPCVNAKS 426
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
C NL ++ C C PG+ C+ ++++C Q D CR+ + YRC C PGY
Sbjct: 427 CKNLIASYYCDCLPGWMG----QNCDININDCLGQCQND-ASCRDLVNGYRCICPPGYA- 480
Query: 185 RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVC 243
++ RD+DEC+ P G C+N + C C GF N C +D++ C C
Sbjct: 481 GDHCERDIDECAS-NPCLNGGHCQNEINRFQCLCPTGFSG---NLCQLDIDYCEPNP--C 534
Query: 244 RNG-RCRNTVGSFRCECAPGYTLTADGRNCRDV-DECDELPHPCGRDGNPSCTNTNGGYE 301
+NG +C N + C+C Y +G+NC + D C P C + SCT +
Sbjct: 535 QNGAQCYNRASDYFCKCPEDY----EGKNCSHLKDHCRTTP--C--EVIDSCTVAMASND 586
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGG-YVCECPAGWRFDKTAAVCVDE 360
G R + + C P+ G+C++ +GG + C+C G+ T C +
Sbjct: 587 TPEGV-------RYISSNVCG--PH----GKCKSQSGGKFTCDCNKGF----TGTYCHEN 629
Query: 361 RKELCYDEWEAGRCHRARPL--QLARPECCCSEGAAW-GRYCERCPAPDSAEFMRICQGG 417
++ E+ C + +C CS+G W G YCE D ++ C G
Sbjct: 630 -----INDCESNPCRNGGTCIDGVNSYKCICSDG--WEGAYCET-NINDCSQ--NPCHNG 679
Query: 418 MGRPNLTQDL----------DECRVRPDVCV------GGRCVNTDGSFRCECPDGYVLAP 461
+L D C R C GG C + +F+C CP G+
Sbjct: 680 GTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW---- 735
Query: 462 DGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRAS 519
+G +C A + P C NG TC + C C G+ +GP C + ++C+
Sbjct: 736 EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGW-EGP--ICAQNTNDCSPHPCY 792
Query: 520 CTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPE 578
+ C + +RC C G+A G CR +I+EC P C + + Y C CP
Sbjct: 793 NSGTCVDGDNWYRCECAPGFA----GPDCRININECQSSPCAFGATCVDEINGYRCVCPP 848
Query: 579 GYRRTSAPQDSENAC----EDINECEEQEDLCSGGVCIN 613
G+ + S C I + + +D C+ C+N
Sbjct: 849 GHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLN 887
Score = 163 bits (396), Expect = 2e-39
Identities = 158/579 (27%), Positives = 242/579 (41%), Gaps = 112/579 (19%)
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIG 172
C G P G + LPG +CRC G++ C D+C C HG C
Sbjct: 234 CRQGCSPKHGSCK---LPG--DCRCQYGWQGL----YC---DKCIPHPGCVHGICNEP-- 279
Query: 173 SYRCECKPGYTLRENVC-RDVDECSRPRPVCRNGTCENL-PGAYLCHCDDGFKAGPNNDC 230
++C C+ + +C +D++ C +P GTC N P Y C C +G+ +GPN +
Sbjct: 280 -WQCLCETNWG--GQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY-SGPNCEI 335
Query: 231 VDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRD 288
+ + C C N G C+ T F CEC+PG+T G C ++D+C P+ C
Sbjct: 336 AE-HACLSDP--CHNRGSCKETSLGFECECSPGWT----GPTCSTNIDDCS--PNNCSHG 386
Query: 289 GNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
G +C + G++C C W G+ C +D +EC+ P V A C+N Y C+C G
Sbjct: 387 G--TCQDLVNGFKCVCPPQW--TGKTCQLDANECEAKPCVNA-KSCKNLIASYYCDCLPG 441
Query: 348 W---RFDKTAAVCVD--ERKELCYDEWEAGRCHRARPLQLARPEC------CCSEGAAWG 396
W D C+ + C D RC P A C C S G
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVNGYRC--ICPPGYAGDHCERDIDECASNPCLNG 499
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQ-DLDECRVRPDVCV-GGRCVNTDGSFRCECP 454
+C+ + F +C G NL Q D+D C P+ C G +C N + C+CP
Sbjct: 500 GHCQN----EINRFQCLCPTGFS-GNLCQLDIDYC--EPNPCQNGAQCYNRASDYFCKCP 552
Query: 455 DGYVLAPDGLSCVD-ADECALDP-------------------------RICG-NGTCSNT 487
+ Y +G +C D C P +CG +G C +
Sbjct: 553 EDY----EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQ 608
Query: 488 RGG-YECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGV 546
GG + C C+ GFT ++++C C + S++C C G+ +G
Sbjct: 609 SGGKFTCDCNKGFT--GTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGW----EGA 662
Query: 547 HCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYR-RTSAPQDSENACEDINECEEQED 604
+C +I++C Q P C ++V + C C G++ +T +DS+ C++ C
Sbjct: 663 YCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ--CDEAT-CN---- 715
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
+GG C + +F C C G+E GT C R +C
Sbjct: 716 --NGGTCYDEGDAFKCMCPGGWE----GTTCNIARNSSC 748
Score = 120 bits (290), Expect = 2e-26
Identities = 90/320 (28%), Positives = 134/320 (41%), Gaps = 47/320 (14%)
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARP---------ECCCSEGAAW-GRYCERC-PAP 405
C + C + W C+RA Q P +C C G W G YC++C P P
Sbjct: 212 CDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYG--WQGLYCDKCIPHP 269
Query: 406 DSAE------FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTD-GSFRCECPDGYV 458
+ +C+ G +DL+ C GG C NT ++C CP+GY
Sbjct: 270 GCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY- 328
Query: 459 LAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGR 517
G +C A+ L G+C T G+EC+CSPG+T GP TC ++D+C+
Sbjct: 329 ---SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWT-GP--TCSTNIDDCSPNN 382
Query: 518 ASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKC 576
S C + F+C CP + G C+ D +EC +P V +C+N++ SY C C
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKSCKNLIASYYCDC 438
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLCDCDAGFEPSEDGTDC 635
G+ +N +IN+C Q C C + + C C G+ D
Sbjct: 439 LPGWM-------GQNCDININDCLGQ---CQNDASCRDLVNGYRCICPPGYAGDHCERDI 488
Query: 636 IDRRTGTCYRSLVSGRCEPE 655
+ + C L G C+ E
Sbjct: 489 DECASNPC---LNGGHCQNE 505
Score = 64.5 bits (150), Expect = 2e-09
Identities = 35/92 (38%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
+RC+C PGY AG+ C D+DECA P C N + CLC TG+ G C+
Sbjct: 471 YRCICPPGY--AGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGF----SGNLCQL 524
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
D+D CE + C N Y C C + YE
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE 556
Score = 56.8 bits (131), Expect = 3e-07
Identities = 55/215 (25%), Positives = 89/215 (41%), Gaps = 36/215 (16%)
Query: 74 MPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNLPG 131
+P C GTC F C C G+E +C ++ ++CS PC CV+
Sbjct: 749 LPNPCHNGGTCVVNGESFTCVCKEGWE----GPICAQNTNDCS--PHPCYNSGTCVDGDN 802
Query: 132 AFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR 190
+ C C PG+ + +C +++EC C + I YRC C PG++ + C+
Sbjct: 803 WYRCECAPGF----AGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAK--CQ 856
Query: 191 DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRN 250
+V RP G+ +P DG K ++DC + +C G + C C
Sbjct: 857 EVS----GRPCITMGSV--IP--------DGAKW--DDDC-NTCQCLNGRIACSKVWC-- 897
Query: 251 TVGSFRCECAPGYTLTADGRNCRDVDECDELPHPC 285
G C G++ G++C + + HPC
Sbjct: 898 --GPRPCLLHKGHSECPSGQSCIPILDDQCFVHPC 930
Score = 46.8 bits (106), Expect = 3e-04
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 761 GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G+F C C G+ G C + +++C P C + SY C+C G+E GA C
Sbjct: 611 GKFTCDCNKGF--TGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWE----GAYC 664
Query: 820 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
++++C ++ C + + C C++G+ +G C
Sbjct: 665 ETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGW--KGKTC 702
Score = 46.4 bits (105), Expect = 4e-04
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F CVC G+ G +CA + ++C+ P C + D Y C C G+ G +CR
Sbjct: 766 FTCVCKEGWE--GPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFA----GPDCRI 819
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
+++EC+ C + Y C C G+
Sbjct: 820 NINECQSSPCAFGATCVDEINGYRCVCPPGH 850
Score = 45.2 bits (102), Expect = 0.001
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F C C PG+ G C+ ++D+C+ C + + C+C + G C+
Sbjct: 358 FECECSPGW--TGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQL 411
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
D +ECE + C N SY C C G+
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDCLPGW 442
Score = 45.2 bits (102), Expect = 0.001
Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 17/120 (14%)
Query: 747 DVDECAAIPGLCAPG------RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D +EC A P + A + C C PG+ G+ C ++++C + D C +
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDCLPGWM--GQNCDININDCLGQCQN-DASCRDLV 468
Query: 800 GSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
Y C+C GY G +C RD+DEC + C N ++C C G+ G+ C
Sbjct: 469 NGYRCICPPGYA----GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFS--GNLC 522
Score = 45.2 bits (102), Expect = 0.001
Identities = 28/120 (23%), Positives = 54/120 (45%), Gaps = 16/120 (13%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
++++C + P G C G ++C+C G+ G C ++++C+ P C +
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWE--GAYCETNINDCSQNPCHNGGTCRDLV 686
Query: 800 GSYDCLCRTGYELDEDGANCRDVD-ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
+ C C+ G++ G C D +C+ T C + +++C C G+E G C
Sbjct: 687 NDFYCDCKNGWK----GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE--GTTC 740
Score = 39.5 bits (88), Expect = 0.050
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 13/94 (13%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC- 819
F+C+C G+ G C + P PC C S+ C+C+ G+E G C
Sbjct: 727 FKCMCPGGWE--GTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE----GPICA 780
Query: 820 RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
++ ++C H C C + + Y C C G+
Sbjct: 781 QNTNDC--SPHPCYNSGTCVDGDNWYRCECAPGF 812
Score = 39.5 bits (88), Expect = 0.050
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 9/70 (12%)
Query: 756 GLCAPGR--FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G C G +RC C PG+ AG C +++EC P C + Y C+C G+
Sbjct: 795 GTCVDGDNWYRCECAPGF--AGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGH-- 850
Query: 813 DEDGANCRDV 822
GA C++V
Sbjct: 851 --SGAKCQEV 858
Score = 35.5 bits (78), Expect = 0.81
Identities = 35/107 (32%), Positives = 46/107 (42%), Gaps = 22/107 (20%)
Query: 751 CAAIPGLCA-PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C+ G C PG RC Y G C D+C P +C+ + CLC T
Sbjct: 238 CSPKHGSCKLPGDCRCQ----YGWQGLYC---DKCIPHPGCVHGICNEP---WQCLCETN 287
Query: 810 YELDEDGANC-RDVDECERDTHT-CQQ--ICSNT-EGSYECSCEDGY 851
+ G C +D++ C TH C CSNT Y+CSC +GY
Sbjct: 288 W----GGQLCDKDLNYC--GTHQPCLNGGTCSNTGPDKYQCSCPEGY 328
>U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jagged
1 protein.
Length = 1218
Score = 202 bits (494), Expect = 3e-51
Identities = 174/649 (26%), Positives = 271/649 (41%), Gaps = 88/649 (13%)
Query: 8 QSCAGAVGVPQTKYLCCCSVGHAW-GAPCEACPPRGSPAHTALCGEKPGEYINPVTNE-- 64
Q C+ G + C C G W G C+ C P H +C E P + + TN
Sbjct: 236 QGCSPKHGSCKLPGDCRCQYG--WQGLYCDKCIPHPGCVH-GICNE-PWQCLCE-TNWGG 290
Query: 65 ---TKPIDECDIMPQLCKPGTCHDT-PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
K ++ C GTC +T P +QC C GY N C ++ E + PC
Sbjct: 291 QLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPN----C-EIAEHACLSDPC 345
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
C FEC C PG+ P+ ++D+C G C++ + ++C C P
Sbjct: 346 HNRGSCKETSLGFECECSPGWT-GPTCST--NIDDCSPNNCSHGGTCQDLVNGFKCVCPP 402
Query: 181 GYTLRENVCR-DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREG 239
+T + C+ D +EC +P +C+NL +Y C C G+ G N D +++N+C
Sbjct: 403 QWTGK--TCQLDANECEA-KPCVNAKSCKNLIASYYCDCLPGWM-GQNCD-ININDCL-- 455
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNG 298
G + CR+ V +RC C PGY G +C RD+DEC +PC G+ C N
Sbjct: 456 GQCQNDASCRDLVNGYRCICPPGYA----GDHCERDIDECAS--NPCLNGGH--CQNEIN 507
Query: 299 GYECSCGAGWKLVGRRC-VDRDECKELPYVCAGG-ECRNFNGGYVCECPAGWRFDKTAAV 356
++C C G+ G C +D D C+ P C G +C N Y C+CP + + +
Sbjct: 508 RFQCLCPTGFS--GNLCQLDIDYCEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHL 563
Query: 357 CVDERKELC--YDEWEAGRCHRARP--LQLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
R C D P ++ C G +C + +F
Sbjct: 564 KDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHG--------KCKSQSGGKFTC 615
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDAD 470
C G +++++C P C GG C++ S++C C DG+ +G C + +
Sbjct: 616 DCNKGFTGTYCHENINDCESNP--CRNGGTCIDGVNSYKCICSDGW----EGAYCETNIN 669
Query: 471 ECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVD-ECAEGRASCTFRCHNTA 528
+C+ +P C NG TC + + C C G+ +TC D +C E + C++
Sbjct: 670 DCSQNP--CHNGGTCRDLVNDFYCDCKNGWK---GKTCHSRDSQCDEATCNNGGTCYDEG 724
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG--SYICKCPEGYRRTSAP 586
+F+C CP G+ +G C P C + VV S+ C C EG+
Sbjct: 725 DAFKCMCPGGW----EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICA 780
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
Q++ N+C + G C++ D + C+C GF G DC
Sbjct: 781 QNT-------NDCSPHP-CYNSGTCVDGDNWYRCECAPGFA----GPDC 817
Score = 170 bits (414), Expect = 2e-41
Identities = 164/607 (27%), Positives = 253/607 (41%), Gaps = 84/607 (13%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCV 127
D+C P C G C++ +QC C+ + LC +D++ C +P C C
Sbjct: 263 DKCIPHPG-CVHGICNEP---WQCLCETNWG----GQLCDKDLNYCGTHQP-CLNGGTCS 313
Query: 128 NL-PGAFECRCPPGYRLTPSLDECEDVDE-CGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
N P ++C CP GY S CE + C + G C+ T + CEC PG+T
Sbjct: 314 NTGPDKYQCSCPEGY----SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWT-G 368
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVCR 244
++D+CS P GTC++L + C C + C +D NEC C
Sbjct: 369 PTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCPPQW---TGKTCQLDANECE--AKPCV 422
Query: 245 NGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS 303
N + C+N + S+ C+C PG+ G+NC D++ D L C D SC + GY C
Sbjct: 423 NAKSCKNLIASYYCDCLPGWM----GQNC-DININDCLGQ-CQNDA--SCRDLVNGYRCI 474
Query: 304 CGAGWKLVGRRCV-DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
C G+ G C D DEC P + GG C+N + C CP G+ + +C
Sbjct: 475 CPPGY--AGDHCERDIDECASNPCL-NGGHCQNEINRFQCLCPTGF----SGNLC----- 522
Query: 363 ELCYDEWEAGRCHRARPLQLARPE--CCCSEGAAWGRYC----ERCPAPDSAEFMRICQG 416
+L D E C + C C E G+ C + C E + C
Sbjct: 523 QLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE-GKNCSHLKDHC-RTTPCEVIDSCTV 580
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVN-TDGSFRCECPDGYVLAPDGLSC-VDADECA 473
M + + + + +VC G+C + + G F C+C G+ G C + ++C
Sbjct: 581 AMASNDTPEGVR--YISSNVCGPHGKCKSQSGGKFTCDCNKGFT----GTYCHENINDCE 634
Query: 474 LDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
+P C N GTC + Y+C CS G+ +T ++++C++ C + F
Sbjct: 635 SNP--CRNGGTCIDGVNSYKCICSDGWEGAYCET--NINDCSQNPCHNGGTCRDLVNDFY 690
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
C C G+ H RD +C + C + ++ C CP G+ T+ ++
Sbjct: 691 CDCKNGW--KGKTCHSRD-SQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSS 747
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP---SEDGTDCIDR---RTGTCYRS 646
C N C +GG C+ SF C C G+E +++ DC +GTC
Sbjct: 748 CLP-NPCH------NGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDG 800
Query: 647 LVSGRCE 653
RCE
Sbjct: 801 DNWYRCE 807
Score = 164 bits (399), Expect = 1e-39
Identities = 175/639 (27%), Positives = 262/639 (41%), Gaps = 115/639 (17%)
Query: 20 KYLCCCSVGHAWGAPCEA---------CPPRGSPAHTAL---CGEKPGEYINPVTNETKP 67
KY C C G++ G CE C RGS T+L C PG + P +
Sbjct: 319 KYQCSCPEGYS-GPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPG-WTGPTCSTN-- 374
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQ 125
ID+C P C G TC D GF+C C + T C+ D +EC PC
Sbjct: 375 IDDCS--PNNCSHGGTCQDLVNGFKCVCPPQW----TGKTCQLDANECE--AKPCVNAKS 426
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
C NL ++ C C PG+ C+ ++++C Q D CR+ + YRC C PGY
Sbjct: 427 CKNLIASYYCDCLPGWMG----QNCDININDCLGQCQND-ASCRDLVNGYRCICPPGYA- 480
Query: 185 RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVC 243
++ RD+DEC+ P G C+N + C C GF N C +D++ C C
Sbjct: 481 GDHCERDIDECAS-NPCLNGGHCQNEINRFQCLCPTGFSG---NLCQLDIDYCEPNP--C 534
Query: 244 RNG-RCRNTVGSFRCECAPGYTLTADGRNCRDV-DECDELPHPCGRDGNPSCTNTNGGYE 301
+NG +C N + C+C Y +G+NC + D C P C + SCT +
Sbjct: 535 QNGAQCYNRASDYFCKCPEDY----EGKNCSHLKDHCRTTP--C--EVIDSCTVAMASND 586
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGG-YVCECPAGWRFDKTAAVCVDE 360
G R + + C P+ G+C++ +GG + C+C G+ T C +
Sbjct: 587 TPEGV-------RYISSNVCG--PH----GKCKSQSGGKFTCDCNKGF----TGTYCHEN 629
Query: 361 RKELCYDEWEAGRCHRARPL--QLARPECCCSEGAAW-GRYCERCPAPDSAEFMRICQGG 417
++ E+ C + +C CS+G W G YCE D ++ C G
Sbjct: 630 -----INDCESNPCRNGGTCIDGVNSYKCICSDG--WEGAYCET-NINDCSQ--NPCHNG 679
Query: 418 MGRPNLTQDL----------DECRVRPDVCV------GGRCVNTDGSFRCECPDGYVLAP 461
+L D C R C GG C + +F+C CP G+
Sbjct: 680 GTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW---- 735
Query: 462 DGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRAS 519
+G +C A + P C NG TC + C C G+ +GP C + ++C+
Sbjct: 736 EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGW-EGP--ICAQNTNDCSPHPCY 792
Query: 520 CTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPE 578
+ C + +RC C G+A G CR +I+EC P C + + Y C CP
Sbjct: 793 NSGTCVDGDNWYRCECAPGFA----GPDCRININECQSSPCAFGATCVDEINGYRCVCPP 848
Query: 579 GYRRTSAPQDSENAC----EDINECEEQEDLCSGGVCIN 613
G+ + S C I + + +D C+ C+N
Sbjct: 849 GHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLN 887
Score = 163 bits (396), Expect = 2e-39
Identities = 158/579 (27%), Positives = 242/579 (41%), Gaps = 112/579 (19%)
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIG 172
C G P G + LPG +CRC G++ C D+C C HG C
Sbjct: 234 CRQGCSPKHGSCK---LPG--DCRCQYGWQGL----YC---DKCIPHPGCVHGICNEP-- 279
Query: 173 SYRCECKPGYTLRENVC-RDVDECSRPRPVCRNGTCENL-PGAYLCHCDDGFKAGPNNDC 230
++C C+ + +C +D++ C +P GTC N P Y C C +G+ +GPN +
Sbjct: 280 -WQCLCETNWG--GQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY-SGPNCEI 335
Query: 231 VDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRD 288
+ + C C N G C+ T F CEC+PG+T G C ++D+C P+ C
Sbjct: 336 AE-HACLSDP--CHNRGSCKETSLGFECECSPGWT----GPTCSTNIDDCS--PNNCSHG 386
Query: 289 GNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
G +C + G++C C W G+ C +D +EC+ P V A C+N Y C+C G
Sbjct: 387 G--TCQDLVNGFKCVCPPQW--TGKTCQLDANECEAKPCVNA-KSCKNLIASYYCDCLPG 441
Query: 348 W---RFDKTAAVCVD--ERKELCYDEWEAGRCHRARPLQLARPEC------CCSEGAAWG 396
W D C+ + C D RC P A C C S G
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVNGYRC--ICPPGYAGDHCERDIDECASNPCLNG 499
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQ-DLDECRVRPDVCV-GGRCVNTDGSFRCECP 454
+C+ + F +C G NL Q D+D C P+ C G +C N + C+CP
Sbjct: 500 GHCQN----EINRFQCLCPTGFS-GNLCQLDIDYC--EPNPCQNGAQCYNRASDYFCKCP 552
Query: 455 DGYVLAPDGLSCVD-ADECALDP-------------------------RICG-NGTCSNT 487
+ Y +G +C D C P +CG +G C +
Sbjct: 553 EDY----EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQ 608
Query: 488 RGG-YECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGV 546
GG + C C+ GFT ++++C C + S++C C G+ +G
Sbjct: 609 SGGKFTCDCNKGFT--GTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGW----EGA 662
Query: 547 HCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYR-RTSAPQDSENACEDINECEEQED 604
+C +I++C Q P C ++V + C C G++ +T +DS+ C++ C
Sbjct: 663 YCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ--CDEAT-CN---- 715
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
+GG C + +F C C G+E GT C R +C
Sbjct: 716 --NGGTCYDEGDAFKCMCPGGWE----GTTCNIARNSSC 748
Score = 120 bits (290), Expect = 2e-26
Identities = 90/320 (28%), Positives = 134/320 (41%), Gaps = 47/320 (14%)
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARP---------ECCCSEGAAW-GRYCERC-PAP 405
C + C + W C+RA Q P +C C G W G YC++C P P
Sbjct: 212 CDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYG--WQGLYCDKCIPHP 269
Query: 406 DSAE------FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTD-GSFRCECPDGYV 458
+ +C+ G +DL+ C GG C NT ++C CP+GY
Sbjct: 270 GCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY- 328
Query: 459 LAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGR 517
G +C A+ L G+C T G+EC+CSPG+T GP TC ++D+C+
Sbjct: 329 ---SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWT-GP--TCSTNIDDCSPNN 382
Query: 518 ASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKC 576
S C + F+C CP + G C+ D +EC +P V +C+N++ SY C C
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKSCKNLIASYYCDC 438
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLCDCDAGFEPSEDGTDC 635
G+ +N +IN+C Q C C + + C C G+ D
Sbjct: 439 LPGWM-------GQNCDININDCLGQ---CQNDASCRDLVNGYRCICPPGYAGDHCERDI 488
Query: 636 IDRRTGTCYRSLVSGRCEPE 655
+ + C L G C+ E
Sbjct: 489 DECASNPC---LNGGHCQNE 505
Score = 64.5 bits (150), Expect = 2e-09
Identities = 35/92 (38%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
+RC+C PGY AG+ C D+DECA P C N + CLC TG+ G C+
Sbjct: 471 YRCICPPGY--AGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGF----SGNLCQL 524
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
D+D CE + C N Y C C + YE
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE 556
Score = 56.8 bits (131), Expect = 3e-07
Identities = 55/215 (25%), Positives = 89/215 (41%), Gaps = 36/215 (16%)
Query: 74 MPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNLPG 131
+P C GTC F C C G+E +C ++ ++CS PC CV+
Sbjct: 749 LPNPCHNGGTCVVNGESFTCVCKEGWE----GPICAQNTNDCS--PHPCYNSGTCVDGDN 802
Query: 132 AFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR 190
+ C C PG+ + +C +++EC C + I YRC C PG++ + C+
Sbjct: 803 WYRCECAPGF----AGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAK--CQ 856
Query: 191 DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRN 250
+V RP G+ +P DG K ++DC + +C G + C C
Sbjct: 857 EVS----GRPCITMGSV--IP--------DGAKW--DDDC-NTCQCLNGRIACSKVWC-- 897
Query: 251 TVGSFRCECAPGYTLTADGRNCRDVDECDELPHPC 285
G C G++ G++C + + HPC
Sbjct: 898 --GPRPCLLHKGHSECPSGQSCIPILDDQCFVHPC 930
Score = 46.8 bits (106), Expect = 3e-04
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 761 GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G+F C C G+ G C + +++C P C + SY C+C G+E GA C
Sbjct: 611 GKFTCDCNKGF--TGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWE----GAYC 664
Query: 820 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
++++C ++ C + + C C++G+ +G C
Sbjct: 665 ETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGW--KGKTC 702
Score = 46.4 bits (105), Expect = 4e-04
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F CVC G+ G +CA + ++C+ P C + D Y C C G+ G +CR
Sbjct: 766 FTCVCKEGWE--GPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFA----GPDCRI 819
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
+++EC+ C + Y C C G+
Sbjct: 820 NINECQSSPCAFGATCVDEINGYRCVCPPGH 850
Score = 45.2 bits (102), Expect = 0.001
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F C C PG+ G C+ ++D+C+ C + + C+C + G C+
Sbjct: 358 FECECSPGW--TGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQL 411
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
D +ECE + C N SY C C G+
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDCLPGW 442
Score = 45.2 bits (102), Expect = 0.001
Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 17/120 (14%)
Query: 747 DVDECAAIPGLCAPG------RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D +EC A P + A + C C PG+ G+ C ++++C + D C +
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDCLPGWM--GQNCDININDCLGQCQN-DASCRDLV 468
Query: 800 GSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
Y C+C GY G +C RD+DEC + C N ++C C G+ G+ C
Sbjct: 469 NGYRCICPPGYA----GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFS--GNLC 522
Score = 45.2 bits (102), Expect = 0.001
Identities = 28/120 (23%), Positives = 54/120 (45%), Gaps = 16/120 (13%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
++++C + P G C G ++C+C G+ G C ++++C+ P C +
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWE--GAYCETNINDCSQNPCHNGGTCRDLV 686
Query: 800 GSYDCLCRTGYELDEDGANCRDVD-ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
+ C C+ G++ G C D +C+ T C + +++C C G+E G C
Sbjct: 687 NDFYCDCKNGWK----GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE--GTTC 740
Score = 39.5 bits (88), Expect = 0.050
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 13/94 (13%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC- 819
F+C+C G+ G C + P PC C S+ C+C+ G+E G C
Sbjct: 727 FKCMCPGGWE--GTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE----GPICA 780
Query: 820 RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
++ ++C H C C + + Y C C G+
Sbjct: 781 QNTNDC--SPHPCYNSGTCVDGDNWYRCECAPGF 812
Score = 39.5 bits (88), Expect = 0.050
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 9/70 (12%)
Query: 756 GLCAPGR--FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G C G +RC C PG+ AG C +++EC P C + Y C+C G+
Sbjct: 795 GTCVDGDNWYRCECAPGF--AGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGH-- 850
Query: 813 DEDGANCRDV 822
GA C++V
Sbjct: 851 --SGAKCQEV 858
Score = 35.5 bits (78), Expect = 0.81
Identities = 35/107 (32%), Positives = 46/107 (42%), Gaps = 22/107 (20%)
Query: 751 CAAIPGLCA-PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C+ G C PG RC Y G C D+C P +C+ + CLC T
Sbjct: 238 CSPKHGSCKLPGDCRCQ----YGWQGLYC---DKCIPHPGCVHGICNEP---WQCLCETN 287
Query: 810 YELDEDGANC-RDVDECERDTHT-CQQ--ICSNT-EGSYECSCEDGY 851
+ G C +D++ C TH C CSNT Y+CSC +GY
Sbjct: 288 W----GGQLCDKDLNYC--GTHQPCLNGGTCSNTGPDKYQCSCPEGY 328
>BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 202 bits (494), Expect = 3e-51
Identities = 174/649 (26%), Positives = 271/649 (41%), Gaps = 88/649 (13%)
Query: 8 QSCAGAVGVPQTKYLCCCSVGHAW-GAPCEACPPRGSPAHTALCGEKPGEYINPVTNE-- 64
Q C+ G + C C G W G C+ C P H +C E P + + TN
Sbjct: 236 QGCSPKHGSCKLPGDCRCQYG--WQGLYCDKCIPHPGCVH-GICNE-PWQCLCE-TNWGG 290
Query: 65 ---TKPIDECDIMPQLCKPGTCHDT-PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
K ++ C GTC +T P +QC C GY N C ++ E + PC
Sbjct: 291 QLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPN----C-EIAEHACLSDPC 345
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
C FEC C PG+ P+ ++D+C G C++ + ++C C P
Sbjct: 346 HNRGSCKETSLGFECECSPGWT-GPTCST--NIDDCSPNNCSHGGTCQDLVNGFKCVCPP 402
Query: 181 GYTLRENVCR-DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREG 239
+T + C+ D +EC +P +C+NL +Y C C G+ G N D +++N+C
Sbjct: 403 QWTGK--TCQLDANECEA-KPCVNAKSCKNLIASYYCDCLPGWM-GQNCD-ININDCL-- 455
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNG 298
G + CR+ V +RC C PGY G +C RD+DEC +PC G+ C N
Sbjct: 456 GQCQNDASCRDLVNGYRCICPPGYA----GDHCERDIDECAS--NPCLNGGH--CQNEIN 507
Query: 299 GYECSCGAGWKLVGRRC-VDRDECKELPYVCAGG-ECRNFNGGYVCECPAGWRFDKTAAV 356
++C C G+ G C +D D C+ P C G +C N Y C+CP + + +
Sbjct: 508 RFQCLCPTGFS--GNLCQLDIDYCEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHL 563
Query: 357 CVDERKELC--YDEWEAGRCHRARP--LQLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
R C D P ++ C G +C + +F
Sbjct: 564 KDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHG--------KCKSQSGGKFTC 615
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDAD 470
C G +++++C P C GG C++ S++C C DG+ +G C + +
Sbjct: 616 DCNKGFTGTYCHENINDCESNP--CRNGGTCIDGVNSYKCICSDGW----EGAYCETNIN 669
Query: 471 ECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVD-ECAEGRASCTFRCHNTA 528
+C+ +P C NG TC + + C C G+ +TC D +C E + C++
Sbjct: 670 DCSQNP--CHNGGTCRDLVNDFYCDCKNGWK---GKTCHSRDSQCDEATCNNGGTCYDEG 724
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG--SYICKCPEGYRRTSAP 586
+F+C CP G+ +G C P C + VV S+ C C EG+
Sbjct: 725 DAFKCMCPGGW----EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICA 780
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
Q++ N+C + G C++ D + C+C GF G DC
Sbjct: 781 QNT-------NDCSPHP-CYNSGTCVDGDNWYRCECAPGFA----GPDC 817
Score = 170 bits (414), Expect = 2e-41
Identities = 164/607 (27%), Positives = 253/607 (41%), Gaps = 84/607 (13%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCV 127
D+C P C G C++ +QC C+ + LC +D++ C +P C C
Sbjct: 263 DKCIPHPG-CVHGICNEP---WQCLCETNWG----GQLCDKDLNYCGTHQP-CLNGGTCS 313
Query: 128 NL-PGAFECRCPPGYRLTPSLDECEDVDE-CGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
N P ++C CP GY S CE + C + G C+ T + CEC PG+T
Sbjct: 314 NTGPDKYQCSCPEGY----SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWT-G 368
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVCR 244
++D+CS P GTC++L + C C + C +D NEC C
Sbjct: 369 PTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCPPQW---TGKTCQLDANECE--AKPCV 422
Query: 245 NGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS 303
N + C+N + S+ C+C PG+ G+NC D++ D L C D SC + GY C
Sbjct: 423 NAKSCKNLIASYYCDCLPGWM----GQNC-DININDCLGQ-CQNDA--SCRDLVNGYRCI 474
Query: 304 CGAGWKLVGRRCV-DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
C G+ G C D DEC P + GG C+N + C CP G+ + +C
Sbjct: 475 CPPGY--AGDHCERDIDECASNPCL-NGGHCQNEINRFQCLCPTGF----SGNLC----- 522
Query: 363 ELCYDEWEAGRCHRARPLQLARPE--CCCSEGAAWGRYC----ERCPAPDSAEFMRICQG 416
+L D E C + C C E G+ C + C E + C
Sbjct: 523 QLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE-GKNCSHLKDHC-RTTPCEVIDSCTV 580
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVN-TDGSFRCECPDGYVLAPDGLSC-VDADECA 473
M + + + + +VC G+C + + G F C+C G+ G C + ++C
Sbjct: 581 AMASNDTPEGVR--YISSNVCGPHGKCKSQSGGKFTCDCNKGFT----GTYCHENINDCE 634
Query: 474 LDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
+P C N GTC + Y+C CS G+ +T ++++C++ C + F
Sbjct: 635 SNP--CRNGGTCIDGVNSYKCICSDGWEGAYCET--NINDCSQNPCHNGGTCRDLVNDFY 690
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
C C G+ H RD +C + C + ++ C CP G+ T+ ++
Sbjct: 691 CDCKNGW--KGKTCHSRD-SQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSS 747
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP---SEDGTDCIDR---RTGTCYRS 646
C N C +GG C+ SF C C G+E +++ DC +GTC
Sbjct: 748 CLP-NPCH------NGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDG 800
Query: 647 LVSGRCE 653
RCE
Sbjct: 801 DNWYRCE 807
Score = 164 bits (399), Expect = 1e-39
Identities = 175/639 (27%), Positives = 262/639 (41%), Gaps = 115/639 (17%)
Query: 20 KYLCCCSVGHAWGAPCEA---------CPPRGSPAHTAL---CGEKPGEYINPVTNETKP 67
KY C C G++ G CE C RGS T+L C PG + P +
Sbjct: 319 KYQCSCPEGYS-GPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPG-WTGPTCSTN-- 374
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQ 125
ID+C P C G TC D GF+C C + T C+ D +EC PC
Sbjct: 375 IDDCS--PNNCSHGGTCQDLVNGFKCVCPPQW----TGKTCQLDANECE--AKPCVNAKS 426
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
C NL ++ C C PG+ C+ ++++C Q D CR+ + YRC C PGY
Sbjct: 427 CKNLIASYYCDCLPGWMG----QNCDININDCLGQCQND-ASCRDLVNGYRCICPPGYA- 480
Query: 185 RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVC 243
++ RD+DEC+ P G C+N + C C GF N C +D++ C C
Sbjct: 481 GDHCERDIDECAS-NPCLNGGHCQNEINRFQCLCPTGFSG---NLCQLDIDYCEPNP--C 534
Query: 244 RNG-RCRNTVGSFRCECAPGYTLTADGRNCRDV-DECDELPHPCGRDGNPSCTNTNGGYE 301
+NG +C N + C+C Y +G+NC + D C P C + SCT +
Sbjct: 535 QNGAQCYNRASDYFCKCPEDY----EGKNCSHLKDHCRTTP--C--EVIDSCTVAMASND 586
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGG-YVCECPAGWRFDKTAAVCVDE 360
G R + + C P+ G+C++ +GG + C+C G+ T C +
Sbjct: 587 TPEGV-------RYISSNVCG--PH----GKCKSQSGGKFTCDCNKGF----TGTYCHEN 629
Query: 361 RKELCYDEWEAGRCHRARPL--QLARPECCCSEGAAW-GRYCERCPAPDSAEFMRICQGG 417
++ E+ C + +C CS+G W G YCE D ++ C G
Sbjct: 630 -----INDCESNPCRNGGTCIDGVNSYKCICSDG--WEGAYCET-NINDCSQ--NPCHNG 679
Query: 418 MGRPNLTQDL----------DECRVRPDVCV------GGRCVNTDGSFRCECPDGYVLAP 461
+L D C R C GG C + +F+C CP G+
Sbjct: 680 GTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW---- 735
Query: 462 DGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRAS 519
+G +C A + P C NG TC + C C G+ +GP C + ++C+
Sbjct: 736 EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGW-EGP--ICAQNTNDCSPHPCY 792
Query: 520 CTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPE 578
+ C + +RC C G+A G CR +I+EC P C + + Y C CP
Sbjct: 793 NSGTCVDGDNWYRCECAPGFA----GPDCRININECQSSPCAFGATCVDEINGYRCVCPP 848
Query: 579 GYRRTSAPQDSENAC----EDINECEEQEDLCSGGVCIN 613
G+ + S C I + + +D C+ C+N
Sbjct: 849 GHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLN 887
Score = 163 bits (396), Expect = 2e-39
Identities = 158/579 (27%), Positives = 242/579 (41%), Gaps = 112/579 (19%)
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIG 172
C G P G + LPG +CRC G++ C D+C C HG C
Sbjct: 234 CRQGCSPKHGSCK---LPG--DCRCQYGWQGL----YC---DKCIPHPGCVHGICNEP-- 279
Query: 173 SYRCECKPGYTLRENVC-RDVDECSRPRPVCRNGTCENL-PGAYLCHCDDGFKAGPNNDC 230
++C C+ + +C +D++ C +P GTC N P Y C C +G+ +GPN +
Sbjct: 280 -WQCLCETNWG--GQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY-SGPNCEI 335
Query: 231 VDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRD 288
+ + C C N G C+ T F CEC+PG+T G C ++D+C P+ C
Sbjct: 336 AE-HACLSDP--CHNRGSCKETSLGFECECSPGWT----GPTCSTNIDDCS--PNNCSHG 386
Query: 289 GNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
G +C + G++C C W G+ C +D +EC+ P V A C+N Y C+C G
Sbjct: 387 G--TCQDLVNGFKCVCPPQW--TGKTCQLDANECEAKPCVNA-KSCKNLIASYYCDCLPG 441
Query: 348 W---RFDKTAAVCVD--ERKELCYDEWEAGRCHRARPLQLARPEC------CCSEGAAWG 396
W D C+ + C D RC P A C C S G
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVNGYRC--ICPPGYAGDHCERDIDECASNPCLNG 499
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQ-DLDECRVRPDVCV-GGRCVNTDGSFRCECP 454
+C+ + F +C G NL Q D+D C P+ C G +C N + C+CP
Sbjct: 500 GHCQN----EINRFQCLCPTGFS-GNLCQLDIDYC--EPNPCQNGAQCYNRASDYFCKCP 552
Query: 455 DGYVLAPDGLSCVD-ADECALDP-------------------------RICG-NGTCSNT 487
+ Y +G +C D C P +CG +G C +
Sbjct: 553 EDY----EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQ 608
Query: 488 RGG-YECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGV 546
GG + C C+ GFT ++++C C + S++C C G+ +G
Sbjct: 609 SGGKFTCDCNKGFT--GTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGW----EGA 662
Query: 547 HCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYR-RTSAPQDSENACEDINECEEQED 604
+C +I++C Q P C ++V + C C G++ +T +DS+ C++ C
Sbjct: 663 YCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ--CDEAT-CN---- 715
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
+GG C + +F C C G+E GT C R +C
Sbjct: 716 --NGGTCYDEGDAFKCMCPGGWE----GTTCNIARNSSC 748
Score = 120 bits (290), Expect = 2e-26
Identities = 90/320 (28%), Positives = 134/320 (41%), Gaps = 47/320 (14%)
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARP---------ECCCSEGAAW-GRYCERC-PAP 405
C + C + W C+RA Q P +C C G W G YC++C P P
Sbjct: 212 CDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYG--WQGLYCDKCIPHP 269
Query: 406 DSAE------FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTD-GSFRCECPDGYV 458
+ +C+ G +DL+ C GG C NT ++C CP+GY
Sbjct: 270 GCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY- 328
Query: 459 LAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGR 517
G +C A+ L G+C T G+EC+CSPG+T GP TC ++D+C+
Sbjct: 329 ---SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWT-GP--TCSTNIDDCSPNN 382
Query: 518 ASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKC 576
S C + F+C CP + G C+ D +EC +P V +C+N++ SY C C
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKSCKNLIASYYCDC 438
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLCDCDAGFEPSEDGTDC 635
G+ +N +IN+C Q C C + + C C G+ D
Sbjct: 439 LPGWM-------GQNCDININDCLGQ---CQNDASCRDLVNGYRCICPPGYAGDHCERDI 488
Query: 636 IDRRTGTCYRSLVSGRCEPE 655
+ + C L G C+ E
Sbjct: 489 DECASNPC---LNGGHCQNE 505
Score = 64.5 bits (150), Expect = 2e-09
Identities = 35/92 (38%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
+RC+C PGY AG+ C D+DECA P C N + CLC TG+ G C+
Sbjct: 471 YRCICPPGY--AGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGF----SGNLCQL 524
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
D+D CE + C N Y C C + YE
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE 556
Score = 56.8 bits (131), Expect = 3e-07
Identities = 55/215 (25%), Positives = 89/215 (41%), Gaps = 36/215 (16%)
Query: 74 MPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNLPG 131
+P C GTC F C C G+E +C ++ ++CS PC CV+
Sbjct: 749 LPNPCHNGGTCVVNGESFTCVCKEGWE----GPICAQNTNDCS--PHPCYNSGTCVDGDN 802
Query: 132 AFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR 190
+ C C PG+ + +C +++EC C + I YRC C PG++ + C+
Sbjct: 803 WYRCECAPGF----AGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAK--CQ 856
Query: 191 DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRN 250
+V RP G+ +P DG K ++DC + +C G + C C
Sbjct: 857 EVS----GRPCITMGSV--IP--------DGAKW--DDDC-NTCQCLNGRIACSKVWC-- 897
Query: 251 TVGSFRCECAPGYTLTADGRNCRDVDECDELPHPC 285
G C G++ G++C + + HPC
Sbjct: 898 --GPRPCLLHKGHSECPSGQSCIPILDDQCFVHPC 930
Score = 46.8 bits (106), Expect = 3e-04
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 761 GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G+F C C G+ G C + +++C P C + SY C+C G+E GA C
Sbjct: 611 GKFTCDCNKGF--TGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWE----GAYC 664
Query: 820 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
++++C ++ C + + C C++G+ +G C
Sbjct: 665 ETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGW--KGKTC 702
Score = 46.4 bits (105), Expect = 4e-04
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F CVC G+ G +CA + ++C+ P C + D Y C C G+ G +CR
Sbjct: 766 FTCVCKEGWE--GPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFA----GPDCRI 819
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
+++EC+ C + Y C C G+
Sbjct: 820 NINECQSSPCAFGATCVDEINGYRCVCPPGH 850
Score = 45.2 bits (102), Expect = 0.001
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F C C PG+ G C+ ++D+C+ C + + C+C + G C+
Sbjct: 358 FECECSPGW--TGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQL 411
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
D +ECE + C N SY C C G+
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDCLPGW 442
Score = 45.2 bits (102), Expect = 0.001
Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 17/120 (14%)
Query: 747 DVDECAAIPGLCAPG------RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D +EC A P + A + C C PG+ G+ C ++++C + D C +
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDCLPGWM--GQNCDININDCLGQCQN-DASCRDLV 468
Query: 800 GSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
Y C+C GY G +C RD+DEC + C N ++C C G+ G+ C
Sbjct: 469 NGYRCICPPGYA----GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFS--GNLC 522
Score = 45.2 bits (102), Expect = 0.001
Identities = 28/120 (23%), Positives = 54/120 (45%), Gaps = 16/120 (13%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
++++C + P G C G ++C+C G+ G C ++++C+ P C +
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWE--GAYCETNINDCSQNPCHNGGTCRDLV 686
Query: 800 GSYDCLCRTGYELDEDGANCRDVD-ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
+ C C+ G++ G C D +C+ T C + +++C C G+E G C
Sbjct: 687 NDFYCDCKNGWK----GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE--GTTC 740
Score = 39.5 bits (88), Expect = 0.050
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 13/94 (13%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC- 819
F+C+C G+ G C + P PC C S+ C+C+ G+E G C
Sbjct: 727 FKCMCPGGWE--GTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE----GPICA 780
Query: 820 RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
++ ++C H C C + + Y C C G+
Sbjct: 781 QNTNDC--SPHPCYNSGTCVDGDNWYRCECAPGF 812
Score = 39.5 bits (88), Expect = 0.050
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 9/70 (12%)
Query: 756 GLCAPGR--FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G C G +RC C PG+ AG C +++EC P C + Y C+C G+
Sbjct: 795 GTCVDGDNWYRCECAPGF--AGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGH-- 850
Query: 813 DEDGANCRDV 822
GA C++V
Sbjct: 851 --SGAKCQEV 858
Score = 35.5 bits (78), Expect = 0.81
Identities = 35/107 (32%), Positives = 46/107 (42%), Gaps = 22/107 (20%)
Query: 751 CAAIPGLCA-PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C+ G C PG RC Y G C D+C P +C+ + CLC T
Sbjct: 238 CSPKHGSCKLPGDCRCQ----YGWQGLYC---DKCIPHPGCVHGICNEP---WQCLCETN 287
Query: 810 YELDEDGANC-RDVDECERDTHT-CQQ--ICSNT-EGSYECSCEDGY 851
+ G C +D++ C TH C CSNT Y+CSC +GY
Sbjct: 288 W----GGQLCDKDLNYC--GTHQPCLNGGTCSNTGPDKYQCSCPEGY 328
>BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 202 bits (494), Expect = 3e-51
Identities = 174/649 (26%), Positives = 271/649 (41%), Gaps = 88/649 (13%)
Query: 8 QSCAGAVGVPQTKYLCCCSVGHAW-GAPCEACPPRGSPAHTALCGEKPGEYINPVTNE-- 64
Q C+ G + C C G W G C+ C P H +C E P + + TN
Sbjct: 236 QGCSPKHGSCKLPGDCRCQYG--WQGLYCDKCIPHPGCVH-GICNE-PWQCLCE-TNWGG 290
Query: 65 ---TKPIDECDIMPQLCKPGTCHDT-PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
K ++ C GTC +T P +QC C GY N C ++ E + PC
Sbjct: 291 QLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPN----C-EIAEHACLSDPC 345
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
C FEC C PG+ P+ ++D+C G C++ + ++C C P
Sbjct: 346 HNRGSCKETSLGFECECSPGWT-GPTCST--NIDDCSPNNCSHGGTCQDLVNGFKCVCPP 402
Query: 181 GYTLRENVCR-DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREG 239
+T + C+ D +EC +P +C+NL +Y C C G+ G N D +++N+C
Sbjct: 403 QWTGK--TCQLDANECEA-KPCVNAKSCKNLIASYYCDCLPGWM-GQNCD-ININDCL-- 455
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNG 298
G + CR+ V +RC C PGY G +C RD+DEC +PC G+ C N
Sbjct: 456 GQCQNDASCRDLVNGYRCICPPGYA----GDHCERDIDECAS--NPCLNGGH--CQNEIN 507
Query: 299 GYECSCGAGWKLVGRRC-VDRDECKELPYVCAGG-ECRNFNGGYVCECPAGWRFDKTAAV 356
++C C G+ G C +D D C+ P C G +C N Y C+CP + + +
Sbjct: 508 RFQCLCPTGFS--GNLCQLDIDYCEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHL 563
Query: 357 CVDERKELC--YDEWEAGRCHRARP--LQLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
R C D P ++ C G +C + +F
Sbjct: 564 KDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHG--------KCKSQSGGKFTC 615
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDAD 470
C G +++++C P C GG C++ S++C C DG+ +G C + +
Sbjct: 616 DCNKGFTGTYCHENINDCESNP--CRNGGTCIDGVNSYKCICSDGW----EGAYCETNIN 669
Query: 471 ECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVD-ECAEGRASCTFRCHNTA 528
+C+ +P C NG TC + + C C G+ +TC D +C E + C++
Sbjct: 670 DCSQNP--CHNGGTCRDLVNDFYCDCKNGWK---GKTCHSRDSQCDEATCNNGGTCYDEG 724
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG--SYICKCPEGYRRTSAP 586
+F+C CP G+ +G C P C + VV S+ C C EG+
Sbjct: 725 DAFKCMCPGGW----EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICA 780
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
Q++ N+C + G C++ D + C+C GF G DC
Sbjct: 781 QNT-------NDCSPHP-CYNSGTCVDGDNWYRCECAPGFA----GPDC 817
Score = 170 bits (414), Expect = 2e-41
Identities = 164/607 (27%), Positives = 253/607 (41%), Gaps = 84/607 (13%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCV 127
D+C P C G C++ +QC C+ + LC +D++ C +P C C
Sbjct: 263 DKCIPHPG-CVHGICNEP---WQCLCETNWG----GQLCDKDLNYCGTHQP-CLNGGTCS 313
Query: 128 NL-PGAFECRCPPGYRLTPSLDECEDVDE-CGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
N P ++C CP GY S CE + C + G C+ T + CEC PG+T
Sbjct: 314 NTGPDKYQCSCPEGY----SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWT-G 368
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVCR 244
++D+CS P GTC++L + C C + C +D NEC C
Sbjct: 369 PTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCPPQW---TGKTCQLDANECE--AKPCV 422
Query: 245 NGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS 303
N + C+N + S+ C+C PG+ G+NC D++ D L C D SC + GY C
Sbjct: 423 NAKSCKNLIASYYCDCLPGWM----GQNC-DININDCLGQ-CQNDA--SCRDLVNGYRCI 474
Query: 304 CGAGWKLVGRRCV-DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
C G+ G C D DEC P + GG C+N + C CP G+ + +C
Sbjct: 475 CPPGY--AGDHCERDIDECASNPCL-NGGHCQNEINRFQCLCPTGF----SGNLC----- 522
Query: 363 ELCYDEWEAGRCHRARPLQLARPE--CCCSEGAAWGRYC----ERCPAPDSAEFMRICQG 416
+L D E C + C C E G+ C + C E + C
Sbjct: 523 QLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE-GKNCSHLKDHC-RTTPCEVIDSCTV 580
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVN-TDGSFRCECPDGYVLAPDGLSC-VDADECA 473
M + + + + +VC G+C + + G F C+C G+ G C + ++C
Sbjct: 581 AMASNDTPEGVR--YISSNVCGPHGKCKSQSGGKFTCDCNKGFT----GTYCHENINDCE 634
Query: 474 LDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
+P C N GTC + Y+C CS G+ +T ++++C++ C + F
Sbjct: 635 SNP--CRNGGTCIDGVNSYKCICSDGWEGAYCET--NINDCSQNPCHNGGTCRDLVNDFY 690
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
C C G+ H RD +C + C + ++ C CP G+ T+ ++
Sbjct: 691 CDCKNGW--KGKTCHSRD-SQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSS 747
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP---SEDGTDCIDR---RTGTCYRS 646
C N C +GG C+ SF C C G+E +++ DC +GTC
Sbjct: 748 CLP-NPCH------NGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDG 800
Query: 647 LVSGRCE 653
RCE
Sbjct: 801 DNWYRCE 807
Score = 164 bits (399), Expect = 1e-39
Identities = 175/639 (27%), Positives = 262/639 (41%), Gaps = 115/639 (17%)
Query: 20 KYLCCCSVGHAWGAPCEA---------CPPRGSPAHTAL---CGEKPGEYINPVTNETKP 67
KY C C G++ G CE C RGS T+L C PG + P +
Sbjct: 319 KYQCSCPEGYS-GPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPG-WTGPTCSTN-- 374
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQ 125
ID+C P C G TC D GF+C C + T C+ D +EC PC
Sbjct: 375 IDDCS--PNNCSHGGTCQDLVNGFKCVCPPQW----TGKTCQLDANECE--AKPCVNAKS 426
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
C NL ++ C C PG+ C+ ++++C Q D CR+ + YRC C PGY
Sbjct: 427 CKNLIASYYCDCLPGWMG----QNCDININDCLGQCQND-ASCRDLVNGYRCICPPGYA- 480
Query: 185 RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVC 243
++ RD+DEC+ P G C+N + C C GF N C +D++ C C
Sbjct: 481 GDHCERDIDECAS-NPCLNGGHCQNEINRFQCLCPTGFSG---NLCQLDIDYCEPNP--C 534
Query: 244 RNG-RCRNTVGSFRCECAPGYTLTADGRNCRDV-DECDELPHPCGRDGNPSCTNTNGGYE 301
+NG +C N + C+C Y +G+NC + D C P C + SCT +
Sbjct: 535 QNGAQCYNRASDYFCKCPEDY----EGKNCSHLKDHCRTTP--C--EVIDSCTVAMASND 586
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGG-YVCECPAGWRFDKTAAVCVDE 360
G R + + C P+ G+C++ +GG + C+C G+ T C +
Sbjct: 587 TPEGV-------RYISSNVCG--PH----GKCKSQSGGKFTCDCNKGF----TGTYCHEN 629
Query: 361 RKELCYDEWEAGRCHRARPL--QLARPECCCSEGAAW-GRYCERCPAPDSAEFMRICQGG 417
++ E+ C + +C CS+G W G YCE D ++ C G
Sbjct: 630 -----INDCESNPCRNGGTCIDGVNSYKCICSDG--WEGAYCET-NINDCSQ--NPCHNG 679
Query: 418 MGRPNLTQDL----------DECRVRPDVCV------GGRCVNTDGSFRCECPDGYVLAP 461
+L D C R C GG C + +F+C CP G+
Sbjct: 680 GTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW---- 735
Query: 462 DGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRAS 519
+G +C A + P C NG TC + C C G+ +GP C + ++C+
Sbjct: 736 EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGW-EGP--ICAQNTNDCSPHPCY 792
Query: 520 CTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPE 578
+ C + +RC C G+A G CR +I+EC P C + + Y C CP
Sbjct: 793 NSGTCVDGDNWYRCECAPGFA----GPDCRININECQSSPCAFGATCVDEINGYRCVCPP 848
Query: 579 GYRRTSAPQDSENAC----EDINECEEQEDLCSGGVCIN 613
G+ + S C I + + +D C+ C+N
Sbjct: 849 GHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLN 887
Score = 163 bits (396), Expect = 2e-39
Identities = 158/579 (27%), Positives = 242/579 (41%), Gaps = 112/579 (19%)
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIG 172
C G P G + LPG +CRC G++ C D+C C HG C
Sbjct: 234 CRQGCSPKHGSCK---LPG--DCRCQYGWQGL----YC---DKCIPHPGCVHGICNEP-- 279
Query: 173 SYRCECKPGYTLRENVC-RDVDECSRPRPVCRNGTCENL-PGAYLCHCDDGFKAGPNNDC 230
++C C+ + +C +D++ C +P GTC N P Y C C +G+ +GPN +
Sbjct: 280 -WQCLCETNWG--GQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY-SGPNCEI 335
Query: 231 VDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRD 288
+ + C C N G C+ T F CEC+PG+T G C ++D+C P+ C
Sbjct: 336 AE-HACLSDP--CHNRGSCKETSLGFECECSPGWT----GPTCSTNIDDCS--PNNCSHG 386
Query: 289 GNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
G +C + G++C C W G+ C +D +EC+ P V A C+N Y C+C G
Sbjct: 387 G--TCQDLVNGFKCVCPPQW--TGKTCQLDANECEAKPCVNA-KSCKNLIASYYCDCLPG 441
Query: 348 W---RFDKTAAVCVD--ERKELCYDEWEAGRCHRARPLQLARPEC------CCSEGAAWG 396
W D C+ + C D RC P A C C S G
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVNGYRC--ICPPGYAGDHCERDIDECASNPCLNG 499
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQ-DLDECRVRPDVCV-GGRCVNTDGSFRCECP 454
+C+ + F +C G NL Q D+D C P+ C G +C N + C+CP
Sbjct: 500 GHCQN----EINRFQCLCPTGFS-GNLCQLDIDYC--EPNPCQNGAQCYNRASDYFCKCP 552
Query: 455 DGYVLAPDGLSCVD-ADECALDP-------------------------RICG-NGTCSNT 487
+ Y +G +C D C P +CG +G C +
Sbjct: 553 EDY----EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQ 608
Query: 488 RGG-YECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGV 546
GG + C C+ GFT ++++C C + S++C C G+ +G
Sbjct: 609 SGGKFTCDCNKGFT--GTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGW----EGA 662
Query: 547 HCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYR-RTSAPQDSENACEDINECEEQED 604
+C +I++C Q P C ++V + C C G++ +T +DS+ C++ C
Sbjct: 663 YCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ--CDEAT-CN---- 715
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
+GG C + +F C C G+E GT C R +C
Sbjct: 716 --NGGTCYDEGDAFKCMCPGGWE----GTTCNIARNSSC 748
Score = 120 bits (290), Expect = 2e-26
Identities = 90/320 (28%), Positives = 134/320 (41%), Gaps = 47/320 (14%)
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARP---------ECCCSEGAAW-GRYCERC-PAP 405
C + C + W C+RA Q P +C C G W G YC++C P P
Sbjct: 212 CDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYG--WQGLYCDKCIPHP 269
Query: 406 DSAE------FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTD-GSFRCECPDGYV 458
+ +C+ G +DL+ C GG C NT ++C CP+GY
Sbjct: 270 GCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY- 328
Query: 459 LAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGR 517
G +C A+ L G+C T G+EC+CSPG+T GP TC ++D+C+
Sbjct: 329 ---SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWT-GP--TCSTNIDDCSPNN 382
Query: 518 ASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKC 576
S C + F+C CP + G C+ D +EC +P V +C+N++ SY C C
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKSCKNLIASYYCDC 438
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLCDCDAGFEPSEDGTDC 635
G+ +N +IN+C Q C C + + C C G+ D
Sbjct: 439 LPGWM-------GQNCDININDCLGQ---CQNDASCRDLVNGYRCICPPGYAGDHCERDI 488
Query: 636 IDRRTGTCYRSLVSGRCEPE 655
+ + C L G C+ E
Sbjct: 489 DECASNPC---LNGGHCQNE 505
Score = 64.5 bits (150), Expect = 2e-09
Identities = 35/92 (38%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
+RC+C PGY AG+ C D+DECA P C N + CLC TG+ G C+
Sbjct: 471 YRCICPPGY--AGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGF----SGNLCQL 524
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
D+D CE + C N Y C C + YE
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE 556
Score = 56.8 bits (131), Expect = 3e-07
Identities = 55/215 (25%), Positives = 89/215 (41%), Gaps = 36/215 (16%)
Query: 74 MPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNLPG 131
+P C GTC F C C G+E +C ++ ++CS PC CV+
Sbjct: 749 LPNPCHNGGTCVVNGESFTCVCKEGWE----GPICAQNTNDCS--PHPCYNSGTCVDGDN 802
Query: 132 AFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR 190
+ C C PG+ + +C +++EC C + I YRC C PG++ + C+
Sbjct: 803 WYRCECAPGF----AGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAK--CQ 856
Query: 191 DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRN 250
+V RP G+ +P DG K ++DC + +C G + C C
Sbjct: 857 EVS----GRPCITMGSV--IP--------DGAKW--DDDC-NTCQCLNGRIACSKVWC-- 897
Query: 251 TVGSFRCECAPGYTLTADGRNCRDVDECDELPHPC 285
G C G++ G++C + + HPC
Sbjct: 898 --GPRPCLLHKGHSECPSGQSCIPILDDQCFVHPC 930
Score = 46.8 bits (106), Expect = 3e-04
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 761 GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G+F C C G+ G C + +++C P C + SY C+C G+E GA C
Sbjct: 611 GKFTCDCNKGF--TGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWE----GAYC 664
Query: 820 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
++++C ++ C + + C C++G+ +G C
Sbjct: 665 ETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGW--KGKTC 702
Score = 46.4 bits (105), Expect = 4e-04
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F CVC G+ G +CA + ++C+ P C + D Y C C G+ G +CR
Sbjct: 766 FTCVCKEGWE--GPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFA----GPDCRI 819
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
+++EC+ C + Y C C G+
Sbjct: 820 NINECQSSPCAFGATCVDEINGYRCVCPPGH 850
Score = 45.2 bits (102), Expect = 0.001
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F C C PG+ G C+ ++D+C+ C + + C+C + G C+
Sbjct: 358 FECECSPGW--TGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQL 411
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
D +ECE + C N SY C C G+
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDCLPGW 442
Score = 45.2 bits (102), Expect = 0.001
Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 17/120 (14%)
Query: 747 DVDECAAIPGLCAPG------RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D +EC A P + A + C C PG+ G+ C ++++C + D C +
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDCLPGWM--GQNCDININDCLGQCQN-DASCRDLV 468
Query: 800 GSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
Y C+C GY G +C RD+DEC + C N ++C C G+ G+ C
Sbjct: 469 NGYRCICPPGYA----GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFS--GNLC 522
Score = 45.2 bits (102), Expect = 0.001
Identities = 28/120 (23%), Positives = 54/120 (45%), Gaps = 16/120 (13%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
++++C + P G C G ++C+C G+ G C ++++C+ P C +
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWE--GAYCETNINDCSQNPCHNGGTCRDLV 686
Query: 800 GSYDCLCRTGYELDEDGANCRDVD-ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
+ C C+ G++ G C D +C+ T C + +++C C G+E G C
Sbjct: 687 NDFYCDCKNGWK----GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE--GTTC 740
Score = 39.5 bits (88), Expect = 0.050
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 13/94 (13%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC- 819
F+C+C G+ G C + P PC C S+ C+C+ G+E G C
Sbjct: 727 FKCMCPGGWE--GTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE----GPICA 780
Query: 820 RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
++ ++C H C C + + Y C C G+
Sbjct: 781 QNTNDC--SPHPCYNSGTCVDGDNWYRCECAPGF 812
Score = 39.5 bits (88), Expect = 0.050
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 9/70 (12%)
Query: 756 GLCAPGR--FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G C G +RC C PG+ AG C +++EC P C + Y C+C G+
Sbjct: 795 GTCVDGDNWYRCECAPGF--AGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGH-- 850
Query: 813 DEDGANCRDV 822
GA C++V
Sbjct: 851 --SGAKCQEV 858
Score = 35.5 bits (78), Expect = 0.81
Identities = 35/107 (32%), Positives = 46/107 (42%), Gaps = 22/107 (20%)
Query: 751 CAAIPGLCA-PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C+ G C PG RC Y G C D+C P +C+ + CLC T
Sbjct: 238 CSPKHGSCKLPGDCRCQ----YGWQGLYC---DKCIPHPGCVHGICNEP---WQCLCETN 287
Query: 810 YELDEDGANC-RDVDECERDTHT-CQQ--ICSNT-EGSYECSCEDGY 851
+ G C +D++ C TH C CSNT Y+CSC +GY
Sbjct: 288 W----GGQLCDKDLNYC--GTHQPCLNGGTCSNTGPDKYQCSCPEGY 328
>BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 202 bits (494), Expect = 3e-51
Identities = 174/649 (26%), Positives = 271/649 (41%), Gaps = 88/649 (13%)
Query: 8 QSCAGAVGVPQTKYLCCCSVGHAW-GAPCEACPPRGSPAHTALCGEKPGEYINPVTNE-- 64
Q C+ G + C C G W G C+ C P H +C E P + + TN
Sbjct: 236 QGCSPKHGSCKLPGDCRCQYG--WQGLYCDKCIPHPGCVH-GICNE-PWQCLCE-TNWGG 290
Query: 65 ---TKPIDECDIMPQLCKPGTCHDT-PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
K ++ C GTC +T P +QC C GY N C ++ E + PC
Sbjct: 291 QLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPN----C-EIAEHACLSDPC 345
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
C FEC C PG+ P+ ++D+C G C++ + ++C C P
Sbjct: 346 HNRGSCKETSLGFECECSPGWT-GPTCST--NIDDCSPNNCSHGGTCQDLVNGFKCVCPP 402
Query: 181 GYTLRENVCR-DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREG 239
+T + C+ D +EC +P +C+NL +Y C C G+ G N D +++N+C
Sbjct: 403 QWTGK--TCQLDANECEA-KPCVNAKSCKNLIASYYCDCLPGWM-GQNCD-ININDCL-- 455
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNG 298
G + CR+ V +RC C PGY G +C RD+DEC +PC G+ C N
Sbjct: 456 GQCQNDASCRDLVNGYRCICPPGYA----GDHCERDIDECAS--NPCLNGGH--CQNEIN 507
Query: 299 GYECSCGAGWKLVGRRC-VDRDECKELPYVCAGG-ECRNFNGGYVCECPAGWRFDKTAAV 356
++C C G+ G C +D D C+ P C G +C N Y C+CP + + +
Sbjct: 508 RFQCLCPTGFS--GNLCQLDIDYCEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHL 563
Query: 357 CVDERKELC--YDEWEAGRCHRARP--LQLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
R C D P ++ C G +C + +F
Sbjct: 564 KDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHG--------KCKSQSGGKFTC 615
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDAD 470
C G +++++C P C GG C++ S++C C DG+ +G C + +
Sbjct: 616 DCNKGFTGTYCHENINDCESNP--CRNGGTCIDGVNSYKCICSDGW----EGAYCETNIN 669
Query: 471 ECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVD-ECAEGRASCTFRCHNTA 528
+C+ +P C NG TC + + C C G+ +TC D +C E + C++
Sbjct: 670 DCSQNP--CHNGGTCRDLVNDFYCDCKNGWK---GKTCHSRDSQCDEATCNNGGTCYDEG 724
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG--SYICKCPEGYRRTSAP 586
+F+C CP G+ +G C P C + VV S+ C C EG+
Sbjct: 725 DAFKCMCPGGW----EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICA 780
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
Q++ N+C + G C++ D + C+C GF G DC
Sbjct: 781 QNT-------NDCSPHP-CYNSGTCVDGDNWYRCECAPGFA----GPDC 817
Score = 170 bits (414), Expect = 2e-41
Identities = 164/607 (27%), Positives = 253/607 (41%), Gaps = 84/607 (13%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCV 127
D+C P C G C++ +QC C+ + LC +D++ C +P C C
Sbjct: 263 DKCIPHPG-CVHGICNEP---WQCLCETNWG----GQLCDKDLNYCGTHQP-CLNGGTCS 313
Query: 128 NL-PGAFECRCPPGYRLTPSLDECEDVDE-CGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
N P ++C CP GY S CE + C + G C+ T + CEC PG+T
Sbjct: 314 NTGPDKYQCSCPEGY----SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWT-G 368
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVCR 244
++D+CS P GTC++L + C C + C +D NEC C
Sbjct: 369 PTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCPPQW---TGKTCQLDANECE--AKPCV 422
Query: 245 NGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS 303
N + C+N + S+ C+C PG+ G+NC D++ D L C D SC + GY C
Sbjct: 423 NAKSCKNLIASYYCDCLPGWM----GQNC-DININDCLGQ-CQNDA--SCRDLVNGYRCI 474
Query: 304 CGAGWKLVGRRCV-DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
C G+ G C D DEC P + GG C+N + C CP G+ + +C
Sbjct: 475 CPPGY--AGDHCERDIDECASNPCL-NGGHCQNEINRFQCLCPTGF----SGNLC----- 522
Query: 363 ELCYDEWEAGRCHRARPLQLARPE--CCCSEGAAWGRYC----ERCPAPDSAEFMRICQG 416
+L D E C + C C E G+ C + C E + C
Sbjct: 523 QLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE-GKNCSHLKDHC-RTTPCEVIDSCTV 580
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVN-TDGSFRCECPDGYVLAPDGLSC-VDADECA 473
M + + + + +VC G+C + + G F C+C G+ G C + ++C
Sbjct: 581 AMASNDTPEGVR--YISSNVCGPHGKCKSQSGGKFTCDCNKGFT----GTYCHENINDCE 634
Query: 474 LDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
+P C N GTC + Y+C CS G+ +T ++++C++ C + F
Sbjct: 635 SNP--CRNGGTCIDGVNSYKCICSDGWEGAYCET--NINDCSQNPCHNGGTCRDLVNDFY 690
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
C C G+ H RD +C + C + ++ C CP G+ T+ ++
Sbjct: 691 CDCKNGW--KGKTCHSRD-SQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSS 747
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP---SEDGTDCIDR---RTGTCYRS 646
C N C +GG C+ SF C C G+E +++ DC +GTC
Sbjct: 748 CLP-NPCH------NGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDG 800
Query: 647 LVSGRCE 653
RCE
Sbjct: 801 DNWYRCE 807
Score = 165 bits (401), Expect = 6e-40
Identities = 175/639 (27%), Positives = 262/639 (41%), Gaps = 115/639 (17%)
Query: 20 KYLCCCSVGHAWGAPCEA---------CPPRGSPAHTAL---CGEKPGEYINPVTNETKP 67
KY C C G++ G CE C RGS T+L C PG + P +
Sbjct: 319 KYQCSCPEGYS-GPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPG-WTGPTCSTN-- 374
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQ 125
ID+C P C G TC D GF+C C + T C+ D +EC PC
Sbjct: 375 IDDCS--PNNCSHGGTCQDLVNGFKCVCPPQW----TGKTCQLDANECE--AKPCVNAKS 426
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
C NL ++ C C PG+ C+ ++++C Q D CR+ + YRC C PGY
Sbjct: 427 CKNLIASYYCDCLPGWMG----QNCDININDCLGQCQND-ASCRDLVNGYRCICPPGYA- 480
Query: 185 RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVC 243
++ RD+DEC+ P G C+N + C C GF N C +D++ C C
Sbjct: 481 GDHCERDIDECAS-NPCLNGGHCQNEINRFQCLCPTGFSG---NLCQLDIDYCEPNP--C 534
Query: 244 RNG-RCRNTVGSFRCECAPGYTLTADGRNCRDV-DECDELPHPCGRDGNPSCTNTNGGYE 301
+NG +C N + C+C Y +G+NC + D C P C + SCT +
Sbjct: 535 QNGAQCYNRASDYFCKCPEDY----EGKNCSHLKDHCRTTP--C--EVIDSCTVAMASND 586
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGG-YVCECPAGWRFDKTAAVCVDE 360
G R + + C P+ G+C++ +GG + C+C G+ T C +
Sbjct: 587 TPEGV-------RYISSNVCG--PH----GKCKSQSGGKFTCDCNKGF----TGTYCHEN 629
Query: 361 RKELCYDEWEAGRCHRARPL--QLARPECCCSEGAAW-GRYCERCPAPDSAEFMRICQGG 417
++ E+ C + +C CS+G W G YCE D ++ C G
Sbjct: 630 -----INDCESNPCRNGGTCIDGVNSYKCICSDG--WEGAYCET-NINDCSQ--NPCHNG 679
Query: 418 MGRPNLTQDL----------DECRVRPDVCV------GGRCVNTDGSFRCECPDGYVLAP 461
+L D C R C GG C + +F+C CP G+
Sbjct: 680 GTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW---- 735
Query: 462 DGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRAS 519
+G +C A + P C NG TC + C C G+ +GP C + ++C+
Sbjct: 736 EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGW-EGP--ICAQNTNDCSPHPCY 792
Query: 520 CTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPE 578
+ C + +RC C G+A G CR +I+EC P C + + Y C CP
Sbjct: 793 NSGTCVDGDNWYRCECAPGFA----GPDCRININECQSSPCAFGATCVDEINGYRCVCPP 848
Query: 579 GYRRTSAPQDSENAC----EDINECEEQEDLCSGGVCIN 613
G+ + S C I + + +D C+ C+N
Sbjct: 849 GHSGAKCQEVSGRPCITMGSVIRDGAKWDDDCNTCQCLN 887
Score = 163 bits (396), Expect = 2e-39
Identities = 158/579 (27%), Positives = 242/579 (41%), Gaps = 112/579 (19%)
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIG 172
C G P G + LPG +CRC G++ C D+C C HG C
Sbjct: 234 CRQGCSPKHGSCK---LPG--DCRCQYGWQGL----YC---DKCIPHPGCVHGICNEP-- 279
Query: 173 SYRCECKPGYTLRENVC-RDVDECSRPRPVCRNGTCENL-PGAYLCHCDDGFKAGPNNDC 230
++C C+ + +C +D++ C +P GTC N P Y C C +G+ +GPN +
Sbjct: 280 -WQCLCETNWG--GQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY-SGPNCEI 335
Query: 231 VDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRD 288
+ + C C N G C+ T F CEC+PG+T G C ++D+C P+ C
Sbjct: 336 AE-HACLSDP--CHNRGSCKETSLGFECECSPGWT----GPTCSTNIDDCS--PNNCSHG 386
Query: 289 GNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
G +C + G++C C W G+ C +D +EC+ P V A C+N Y C+C G
Sbjct: 387 G--TCQDLVNGFKCVCPPQW--TGKTCQLDANECEAKPCVNA-KSCKNLIASYYCDCLPG 441
Query: 348 W---RFDKTAAVCVD--ERKELCYDEWEAGRCHRARPLQLARPEC------CCSEGAAWG 396
W D C+ + C D RC P A C C S G
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVNGYRC--ICPPGYAGDHCERDIDECASNPCLNG 499
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQ-DLDECRVRPDVCV-GGRCVNTDGSFRCECP 454
+C+ + F +C G NL Q D+D C P+ C G +C N + C+CP
Sbjct: 500 GHCQN----EINRFQCLCPTGFS-GNLCQLDIDYC--EPNPCQNGAQCYNRASDYFCKCP 552
Query: 455 DGYVLAPDGLSCVD-ADECALDP-------------------------RICG-NGTCSNT 487
+ Y +G +C D C P +CG +G C +
Sbjct: 553 EDY----EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQ 608
Query: 488 RGG-YECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGV 546
GG + C C+ GFT ++++C C + S++C C G+ +G
Sbjct: 609 SGGKFTCDCNKGFT--GTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGW----EGA 662
Query: 547 HCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYR-RTSAPQDSENACEDINECEEQED 604
+C +I++C Q P C ++V + C C G++ +T +DS+ C++ C
Sbjct: 663 YCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ--CDEAT-CN---- 715
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
+GG C + +F C C G+E GT C R +C
Sbjct: 716 --NGGTCYDEGDAFKCMCPGGWE----GTTCNIARNSSC 748
Score = 120 bits (290), Expect = 2e-26
Identities = 90/320 (28%), Positives = 134/320 (41%), Gaps = 47/320 (14%)
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARP---------ECCCSEGAAW-GRYCERC-PAP 405
C + C + W C+RA Q P +C C G W G YC++C P P
Sbjct: 212 CDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYG--WQGLYCDKCIPHP 269
Query: 406 DSAE------FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTD-GSFRCECPDGYV 458
+ +C+ G +DL+ C GG C NT ++C CP+GY
Sbjct: 270 GCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY- 328
Query: 459 LAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGR 517
G +C A+ L G+C T G+EC+CSPG+T GP TC ++D+C+
Sbjct: 329 ---SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWT-GP--TCSTNIDDCSPNN 382
Query: 518 ASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKC 576
S C + F+C CP + G C+ D +EC +P V +C+N++ SY C C
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKSCKNLIASYYCDC 438
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLCDCDAGFEPSEDGTDC 635
G+ +N +IN+C Q C C + + C C G+ D
Sbjct: 439 LPGWM-------GQNCDININDCLGQ---CQNDASCRDLVNGYRCICPPGYAGDHCERDI 488
Query: 636 IDRRTGTCYRSLVSGRCEPE 655
+ + C L G C+ E
Sbjct: 489 DECASNPC---LNGGHCQNE 505
Score = 64.5 bits (150), Expect = 2e-09
Identities = 35/92 (38%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
+RC+C PGY AG+ C D+DECA P C N + CLC TG+ G C+
Sbjct: 471 YRCICPPGY--AGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGF----SGNLCQL 524
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
D+D CE + C N Y C C + YE
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE 556
Score = 55.6 bits (128), Expect = 7e-07
Identities = 54/215 (25%), Positives = 87/215 (40%), Gaps = 36/215 (16%)
Query: 74 MPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNLPG 131
+P C GTC F C C G+E +C ++ ++CS PC CV+
Sbjct: 749 LPNPCHNGGTCVVNGESFTCVCKEGWE----GPICAQNTNDCS--PHPCYNSGTCVDGDN 802
Query: 132 AFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR 190
+ C C PG+ + +C +++EC C + I YRC C PG++ + C+
Sbjct: 803 WYRCECAPGF----AGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAK--CQ 856
Query: 191 DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRN 250
+V RP G+ DG K ++DC + +C G + C C
Sbjct: 857 EVS----GRPCITMGSV----------IRDGAKW--DDDC-NTCQCLNGRIACSKVWC-- 897
Query: 251 TVGSFRCECAPGYTLTADGRNCRDVDECDELPHPC 285
G C G++ G++C + + HPC
Sbjct: 898 --GPRPCLLHKGHSECPSGQSCIPILDDQCFVHPC 930
Score = 46.8 bits (106), Expect = 3e-04
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 761 GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G+F C C G+ G C + +++C P C + SY C+C G+E GA C
Sbjct: 611 GKFTCDCNKGF--TGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWE----GAYC 664
Query: 820 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
++++C ++ C + + C C++G+ +G C
Sbjct: 665 ETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGW--KGKTC 702
Score = 46.4 bits (105), Expect = 4e-04
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F CVC G+ G +CA + ++C+ P C + D Y C C G+ G +CR
Sbjct: 766 FTCVCKEGWE--GPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFA----GPDCRI 819
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
+++EC+ C + Y C C G+
Sbjct: 820 NINECQSSPCAFGATCVDEINGYRCVCPPGH 850
Score = 45.2 bits (102), Expect = 0.001
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F C C PG+ G C+ ++D+C+ C + + C+C + G C+
Sbjct: 358 FECECSPGW--TGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQL 411
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
D +ECE + C N SY C C G+
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDCLPGW 442
Score = 45.2 bits (102), Expect = 0.001
Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 17/120 (14%)
Query: 747 DVDECAAIPGLCAPG------RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D +EC A P + A + C C PG+ G+ C ++++C + D C +
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDCLPGWM--GQNCDININDCLGQCQN-DASCRDLV 468
Query: 800 GSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
Y C+C GY G +C RD+DEC + C N ++C C G+ G+ C
Sbjct: 469 NGYRCICPPGYA----GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFS--GNLC 522
Score = 45.2 bits (102), Expect = 0.001
Identities = 28/120 (23%), Positives = 54/120 (45%), Gaps = 16/120 (13%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
++++C + P G C G ++C+C G+ G C ++++C+ P C +
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWE--GAYCETNINDCSQNPCHNGGTCRDLV 686
Query: 800 GSYDCLCRTGYELDEDGANCRDVD-ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
+ C C+ G++ G C D +C+ T C + +++C C G+E G C
Sbjct: 687 NDFYCDCKNGWK----GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE--GTTC 740
Score = 39.5 bits (88), Expect = 0.050
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 13/94 (13%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC- 819
F+C+C G+ G C + P PC C S+ C+C+ G+E G C
Sbjct: 727 FKCMCPGGWE--GTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE----GPICA 780
Query: 820 RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
++ ++C H C C + + Y C C G+
Sbjct: 781 QNTNDC--SPHPCYNSGTCVDGDNWYRCECAPGF 812
Score = 39.5 bits (88), Expect = 0.050
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 9/70 (12%)
Query: 756 GLCAPGR--FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G C G +RC C PG+ AG C +++EC P C + Y C+C G+
Sbjct: 795 GTCVDGDNWYRCECAPGF--AGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGH-- 850
Query: 813 DEDGANCRDV 822
GA C++V
Sbjct: 851 --SGAKCQEV 858
Score = 35.5 bits (78), Expect = 0.81
Identities = 35/107 (32%), Positives = 46/107 (42%), Gaps = 22/107 (20%)
Query: 751 CAAIPGLCA-PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C+ G C PG RC Y G C D+C P +C+ + CLC T
Sbjct: 238 CSPKHGSCKLPGDCRCQ----YGWQGLYC---DKCIPHPGCVHGICNEP---WQCLCETN 287
Query: 810 YELDEDGANC-RDVDECERDTHT-CQQ--ICSNT-EGSYECSCEDGY 851
+ G C +D++ C TH C CSNT Y+CSC +GY
Sbjct: 288 W----GGQLCDKDLNYC--GTHQPCLNGGTCSNTGPDKYQCSCPEGY 328
>AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 202 bits (494), Expect = 3e-51
Identities = 174/649 (26%), Positives = 271/649 (41%), Gaps = 88/649 (13%)
Query: 8 QSCAGAVGVPQTKYLCCCSVGHAW-GAPCEACPPRGSPAHTALCGEKPGEYINPVTNE-- 64
Q C+ G + C C G W G C+ C P H +C E P + + TN
Sbjct: 236 QGCSPKHGSCKLPGDCRCQYG--WQGLYCDKCIPHPGCVH-GICNE-PWQCLCE-TNWGG 290
Query: 65 ---TKPIDECDIMPQLCKPGTCHDT-PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
K ++ C GTC +T P +QC C GY N C ++ E + PC
Sbjct: 291 QLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPN----C-EIAEHACLSDPC 345
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
C FEC C PG+ P+ ++D+C G C++ + ++C C P
Sbjct: 346 HNRGSCKETSLGFECECSPGWT-GPTCST--NIDDCSPNNCSHGGTCQDLVNGFKCVCPP 402
Query: 181 GYTLRENVCR-DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREG 239
+T + C+ D +EC +P +C+NL +Y C C G+ G N D +++N+C
Sbjct: 403 QWTGK--TCQLDANECEA-KPCVNAKSCKNLIASYYCDCLPGWM-GQNCD-ININDCL-- 455
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNG 298
G + CR+ V +RC C PGY G +C RD+DEC +PC G+ C N
Sbjct: 456 GQCQNDASCRDLVNGYRCICPPGYA----GDHCERDIDECAS--NPCLNGGH--CQNEIN 507
Query: 299 GYECSCGAGWKLVGRRC-VDRDECKELPYVCAGG-ECRNFNGGYVCECPAGWRFDKTAAV 356
++C C G+ G C +D D C+ P C G +C N Y C+CP + + +
Sbjct: 508 RFQCLCPTGFS--GNLCQLDIDYCEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHL 563
Query: 357 CVDERKELC--YDEWEAGRCHRARP--LQLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
R C D P ++ C G +C + +F
Sbjct: 564 KDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHG--------KCKSQSGGKFTC 615
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDAD 470
C G +++++C P C GG C++ S++C C DG+ +G C + +
Sbjct: 616 DCNKGFTGTYCHENINDCESNP--CRNGGTCIDGVNSYKCICSDGW----EGAYCETNIN 669
Query: 471 ECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVD-ECAEGRASCTFRCHNTA 528
+C+ +P C NG TC + + C C G+ +TC D +C E + C++
Sbjct: 670 DCSQNP--CHNGGTCRDLVNDFYCDCKNGWK---GKTCHSRDSQCDEATCNNGGTCYDEG 724
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG--SYICKCPEGYRRTSAP 586
+F+C CP G+ +G C P C + VV S+ C C EG+
Sbjct: 725 DAFKCMCPGGW----EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICA 780
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
Q++ N+C + G C++ D + C+C GF G DC
Sbjct: 781 QNT-------NDCSPHP-CYNSGTCVDGDNWYRCECAPGFA----GPDC 817
Score = 170 bits (414), Expect = 2e-41
Identities = 164/607 (27%), Positives = 253/607 (41%), Gaps = 84/607 (13%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCV 127
D+C P C G C++ +QC C+ + LC +D++ C +P C C
Sbjct: 263 DKCIPHPG-CVHGICNEP---WQCLCETNWG----GQLCDKDLNYCGTHQP-CLNGGTCS 313
Query: 128 NL-PGAFECRCPPGYRLTPSLDECEDVDE-CGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
N P ++C CP GY S CE + C + G C+ T + CEC PG+T
Sbjct: 314 NTGPDKYQCSCPEGY----SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWT-G 368
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVCR 244
++D+CS P GTC++L + C C + C +D NEC C
Sbjct: 369 PTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCPPQW---TGKTCQLDANECE--AKPCV 422
Query: 245 NGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS 303
N + C+N + S+ C+C PG+ G+NC D++ D L C D SC + GY C
Sbjct: 423 NAKSCKNLIASYYCDCLPGWM----GQNC-DININDCLGQ-CQNDA--SCRDLVNGYRCI 474
Query: 304 CGAGWKLVGRRCV-DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
C G+ G C D DEC P + GG C+N + C CP G+ + +C
Sbjct: 475 CPPGY--AGDHCERDIDECASNPCL-NGGHCQNEINRFQCLCPTGF----SGNLC----- 522
Query: 363 ELCYDEWEAGRCHRARPLQLARPE--CCCSEGAAWGRYC----ERCPAPDSAEFMRICQG 416
+L D E C + C C E G+ C + C E + C
Sbjct: 523 QLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE-GKNCSHLKDHC-RTTPCEVIDSCTV 580
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVN-TDGSFRCECPDGYVLAPDGLSC-VDADECA 473
M + + + + +VC G+C + + G F C+C G+ G C + ++C
Sbjct: 581 AMASNDTPEGVR--YISSNVCGPHGKCKSQSGGKFTCDCNKGFT----GTYCHENINDCE 634
Query: 474 LDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
+P C N GTC + Y+C CS G+ +T ++++C++ C + F
Sbjct: 635 SNP--CRNGGTCIDGVNSYKCICSDGWEGAYCET--NINDCSQNPCHNGGTCRDLVNDFY 690
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
C C G+ H RD +C + C + ++ C CP G+ T+ ++
Sbjct: 691 CDCKNGW--KGKTCHSRD-SQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSS 747
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP---SEDGTDCIDR---RTGTCYRS 646
C N C +GG C+ SF C C G+E +++ DC +GTC
Sbjct: 748 CLP-NPCH------NGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDG 800
Query: 647 LVSGRCE 653
RCE
Sbjct: 801 DNWYRCE 807
Score = 164 bits (399), Expect = 1e-39
Identities = 175/639 (27%), Positives = 262/639 (41%), Gaps = 115/639 (17%)
Query: 20 KYLCCCSVGHAWGAPCEA---------CPPRGSPAHTAL---CGEKPGEYINPVTNETKP 67
KY C C G++ G CE C RGS T+L C PG + P +
Sbjct: 319 KYQCSCPEGYS-GPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPG-WTGPTCSTN-- 374
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQ 125
ID+C P C G TC D GF+C C + T C+ D +EC PC
Sbjct: 375 IDDCS--PNNCSHGGTCQDLVNGFKCVCPPQW----TGKTCQLDANECE--AKPCVNAKS 426
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
C NL ++ C C PG+ C+ ++++C Q D CR+ + YRC C PGY
Sbjct: 427 CKNLIASYYCDCLPGWMG----QNCDININDCLGQCQND-ASCRDLVNGYRCICPPGYA- 480
Query: 185 RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVC 243
++ RD+DEC+ P G C+N + C C GF N C +D++ C C
Sbjct: 481 GDHCERDIDECAS-NPCLNGGHCQNEINRFQCLCPTGFSG---NLCQLDIDYCEPNP--C 534
Query: 244 RNG-RCRNTVGSFRCECAPGYTLTADGRNCRDV-DECDELPHPCGRDGNPSCTNTNGGYE 301
+NG +C N + C+C Y +G+NC + D C P C + SCT +
Sbjct: 535 QNGAQCYNRASDYFCKCPEDY----EGKNCSHLKDHCRTTP--C--EVIDSCTVAMASND 586
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGG-YVCECPAGWRFDKTAAVCVDE 360
G R + + C P+ G+C++ +GG + C+C G+ T C +
Sbjct: 587 TPEGV-------RYISSNVCG--PH----GKCKSQSGGKFTCDCNKGF----TGTYCHEN 629
Query: 361 RKELCYDEWEAGRCHRARPL--QLARPECCCSEGAAW-GRYCERCPAPDSAEFMRICQGG 417
++ E+ C + +C CS+G W G YCE D ++ C G
Sbjct: 630 -----INDCESNPCRNGGTCIDGVNSYKCICSDG--WEGAYCET-NINDCSQ--NPCHNG 679
Query: 418 MGRPNLTQDL----------DECRVRPDVCV------GGRCVNTDGSFRCECPDGYVLAP 461
+L D C R C GG C + +F+C CP G+
Sbjct: 680 GTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW---- 735
Query: 462 DGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRAS 519
+G +C A + P C NG TC + C C G+ +GP C + ++C+
Sbjct: 736 EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGW-EGP--ICAQNTNDCSPHPCY 792
Query: 520 CTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPE 578
+ C + +RC C G+A G CR +I+EC P C + + Y C CP
Sbjct: 793 NSGTCVDGDNWYRCECAPGFA----GPDCRININECQSSPCAFGATCVDEINGYRCVCPP 848
Query: 579 GYRRTSAPQDSENAC----EDINECEEQEDLCSGGVCIN 613
G+ + S C I + + +D C+ C+N
Sbjct: 849 GHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLN 887
Score = 163 bits (396), Expect = 2e-39
Identities = 158/579 (27%), Positives = 242/579 (41%), Gaps = 112/579 (19%)
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIG 172
C G P G + LPG +CRC G++ C D+C C HG C
Sbjct: 234 CRQGCSPKHGSCK---LPG--DCRCQYGWQGL----YC---DKCIPHPGCVHGICNEP-- 279
Query: 173 SYRCECKPGYTLRENVC-RDVDECSRPRPVCRNGTCENL-PGAYLCHCDDGFKAGPNNDC 230
++C C+ + +C +D++ C +P GTC N P Y C C +G+ +GPN +
Sbjct: 280 -WQCLCETNWG--GQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY-SGPNCEI 335
Query: 231 VDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRD 288
+ + C C N G C+ T F CEC+PG+T G C ++D+C P+ C
Sbjct: 336 AE-HACLSDP--CHNRGSCKETSLGFECECSPGWT----GPTCSTNIDDCS--PNNCSHG 386
Query: 289 GNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
G +C + G++C C W G+ C +D +EC+ P V A C+N Y C+C G
Sbjct: 387 G--TCQDLVNGFKCVCPPQW--TGKTCQLDANECEAKPCVNA-KSCKNLIASYYCDCLPG 441
Query: 348 W---RFDKTAAVCVD--ERKELCYDEWEAGRCHRARPLQLARPEC------CCSEGAAWG 396
W D C+ + C D RC P A C C S G
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVNGYRC--ICPPGYAGDHCERDIDECASNPCLNG 499
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQ-DLDECRVRPDVCV-GGRCVNTDGSFRCECP 454
+C+ + F +C G NL Q D+D C P+ C G +C N + C+CP
Sbjct: 500 GHCQN----EINRFQCLCPTGFS-GNLCQLDIDYC--EPNPCQNGAQCYNRASDYFCKCP 552
Query: 455 DGYVLAPDGLSCVD-ADECALDP-------------------------RICG-NGTCSNT 487
+ Y +G +C D C P +CG +G C +
Sbjct: 553 EDY----EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQ 608
Query: 488 RGG-YECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGV 546
GG + C C+ GFT ++++C C + S++C C G+ +G
Sbjct: 609 SGGKFTCDCNKGFT--GTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGW----EGA 662
Query: 547 HCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYR-RTSAPQDSENACEDINECEEQED 604
+C +I++C Q P C ++V + C C G++ +T +DS+ C++ C
Sbjct: 663 YCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ--CDEAT-CN---- 715
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
+GG C + +F C C G+E GT C R +C
Sbjct: 716 --NGGTCYDEGDAFKCMCPGGWE----GTTCNIARNSSC 748
Score = 120 bits (290), Expect = 2e-26
Identities = 90/320 (28%), Positives = 134/320 (41%), Gaps = 47/320 (14%)
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARP---------ECCCSEGAAW-GRYCERC-PAP 405
C + C + W C+RA Q P +C C G W G YC++C P P
Sbjct: 212 CDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYG--WQGLYCDKCIPHP 269
Query: 406 DSAE------FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTD-GSFRCECPDGYV 458
+ +C+ G +DL+ C GG C NT ++C CP+GY
Sbjct: 270 GCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY- 328
Query: 459 LAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGR 517
G +C A+ L G+C T G+EC+CSPG+T GP TC ++D+C+
Sbjct: 329 ---SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWT-GP--TCSTNIDDCSPNN 382
Query: 518 ASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKC 576
S C + F+C CP + G C+ D +EC +P V +C+N++ SY C C
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKSCKNLIASYYCDC 438
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLCDCDAGFEPSEDGTDC 635
G+ +N +IN+C Q C C + + C C G+ D
Sbjct: 439 LPGWM-------GQNCDININDCLGQ---CQNDASCRDLVNGYRCICPPGYAGDHCERDI 488
Query: 636 IDRRTGTCYRSLVSGRCEPE 655
+ + C L G C+ E
Sbjct: 489 DECASNPC---LNGGHCQNE 505
Score = 64.5 bits (150), Expect = 2e-09
Identities = 35/92 (38%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
+RC+C PGY AG+ C D+DECA P C N + CLC TG+ G C+
Sbjct: 471 YRCICPPGY--AGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGF----SGNLCQL 524
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
D+D CE + C N Y C C + YE
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE 556
Score = 56.8 bits (131), Expect = 3e-07
Identities = 55/215 (25%), Positives = 89/215 (41%), Gaps = 36/215 (16%)
Query: 74 MPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNLPG 131
+P C GTC F C C G+E +C ++ ++CS PC CV+
Sbjct: 749 LPNPCHNGGTCVVNGESFTCVCKEGWE----GPICAQNTNDCS--PHPCYNSGTCVDGDN 802
Query: 132 AFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR 190
+ C C PG+ + +C +++EC C + I YRC C PG++ + C+
Sbjct: 803 WYRCECAPGF----AGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAK--CQ 856
Query: 191 DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRN 250
+V RP G+ +P DG K ++DC + +C G + C C
Sbjct: 857 EVS----GRPCITMGSV--IP--------DGAKW--DDDC-NTCQCLNGRIACSKVWC-- 897
Query: 251 TVGSFRCECAPGYTLTADGRNCRDVDECDELPHPC 285
G C G++ G++C + + HPC
Sbjct: 898 --GPRPCLLHKGHSECPSGQSCIPILDDQCFVHPC 930
Score = 46.8 bits (106), Expect = 3e-04
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 761 GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G+F C C G+ G C + +++C P C + SY C+C G+E GA C
Sbjct: 611 GKFTCDCNKGF--TGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWE----GAYC 664
Query: 820 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
++++C ++ C + + C C++G+ +G C
Sbjct: 665 ETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGW--KGKTC 702
Score = 46.4 bits (105), Expect = 4e-04
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F CVC G+ G +CA + ++C+ P C + D Y C C G+ G +CR
Sbjct: 766 FTCVCKEGWE--GPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFA----GPDCRI 819
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
+++EC+ C + Y C C G+
Sbjct: 820 NINECQSSPCAFGATCVDEINGYRCVCPPGH 850
Score = 45.2 bits (102), Expect = 0.001
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F C C PG+ G C+ ++D+C+ C + + C+C + G C+
Sbjct: 358 FECECSPGW--TGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQL 411
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
D +ECE + C N SY C C G+
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDCLPGW 442
Score = 45.2 bits (102), Expect = 0.001
Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 17/120 (14%)
Query: 747 DVDECAAIPGLCAPG------RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D +EC A P + A + C C PG+ G+ C ++++C + D C +
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDCLPGWM--GQNCDININDCLGQCQN-DASCRDLV 468
Query: 800 GSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
Y C+C GY G +C RD+DEC + C N ++C C G+ G+ C
Sbjct: 469 NGYRCICPPGYA----GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFS--GNLC 522
Score = 45.2 bits (102), Expect = 0.001
Identities = 28/120 (23%), Positives = 54/120 (45%), Gaps = 16/120 (13%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
++++C + P G C G ++C+C G+ G C ++++C+ P C +
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWE--GAYCETNINDCSQNPCHNGGTCRDLV 686
Query: 800 GSYDCLCRTGYELDEDGANCRDVD-ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
+ C C+ G++ G C D +C+ T C + +++C C G+E G C
Sbjct: 687 NDFYCDCKNGWK----GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE--GTTC 740
Score = 39.5 bits (88), Expect = 0.050
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 13/94 (13%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC- 819
F+C+C G+ G C + P PC C S+ C+C+ G+E G C
Sbjct: 727 FKCMCPGGWE--GTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE----GPICA 780
Query: 820 RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
++ ++C H C C + + Y C C G+
Sbjct: 781 QNTNDC--SPHPCYNSGTCVDGDNWYRCECAPGF 812
Score = 39.5 bits (88), Expect = 0.050
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 9/70 (12%)
Query: 756 GLCAPGR--FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G C G +RC C PG+ AG C +++EC P C + Y C+C G+
Sbjct: 795 GTCVDGDNWYRCECAPGF--AGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGH-- 850
Query: 813 DEDGANCRDV 822
GA C++V
Sbjct: 851 --SGAKCQEV 858
Score = 35.5 bits (78), Expect = 0.81
Identities = 35/107 (32%), Positives = 46/107 (42%), Gaps = 22/107 (20%)
Query: 751 CAAIPGLCA-PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C+ G C PG RC Y G C D+C P +C+ + CLC T
Sbjct: 238 CSPKHGSCKLPGDCRCQ----YGWQGLYC---DKCIPHPGCVHGICNEP---WQCLCETN 287
Query: 810 YELDEDGANC-RDVDECERDTHT-CQQ--ICSNT-EGSYECSCEDGY 851
+ G C +D++ C TH C CSNT Y+CSC +GY
Sbjct: 288 W----GGQLCDKDLNYC--GTHQPCLNGGTCSNTGPDKYQCSCPEGY 328
>AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein
Jagged 1 protein.
Length = 1218
Score = 202 bits (494), Expect = 3e-51
Identities = 174/649 (26%), Positives = 271/649 (41%), Gaps = 88/649 (13%)
Query: 8 QSCAGAVGVPQTKYLCCCSVGHAW-GAPCEACPPRGSPAHTALCGEKPGEYINPVTNE-- 64
Q C+ G + C C G W G C+ C P H +C E P + + TN
Sbjct: 236 QGCSPKHGSCKLPGDCRCQYG--WQGLYCDKCIPHPGCVH-GICNE-PWQCLCE-TNWGG 290
Query: 65 ---TKPIDECDIMPQLCKPGTCHDT-PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
K ++ C GTC +T P +QC C GY N C ++ E + PC
Sbjct: 291 QLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPN----C-EIAEHACLSDPC 345
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
C FEC C PG+ P+ ++D+C G C++ + ++C C P
Sbjct: 346 HNRGSCKETSLGFECECSPGWT-GPTCST--NIDDCSPNNCSHGGTCQDLVNGFKCVCPP 402
Query: 181 GYTLRENVCR-DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREG 239
+T + C+ D +EC +P +C+NL +Y C C G+ G N D +++N+C
Sbjct: 403 QWTGK--TCQLDANECEA-KPCVNAKSCKNLIASYYCDCLPGWM-GQNCD-ININDCL-- 455
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNG 298
G + CR+ V +RC C PGY G +C RD+DEC +PC G+ C N
Sbjct: 456 GQCQNDASCRDLVNGYRCICPPGYA----GDHCERDIDECAS--NPCLNGGH--CQNEIN 507
Query: 299 GYECSCGAGWKLVGRRC-VDRDECKELPYVCAGG-ECRNFNGGYVCECPAGWRFDKTAAV 356
++C C G+ G C +D D C+ P C G +C N Y C+CP + + +
Sbjct: 508 RFQCLCPTGFS--GNLCQLDIDYCEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHL 563
Query: 357 CVDERKELC--YDEWEAGRCHRARP--LQLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
R C D P ++ C G +C + +F
Sbjct: 564 KDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHG--------KCKSQSGGKFTC 615
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDAD 470
C G +++++C P C GG C++ S++C C DG+ +G C + +
Sbjct: 616 DCNKGFTGTYCHENINDCESNP--CRNGGTCIDGVNSYKCICSDGW----EGAYCETNIN 669
Query: 471 ECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVD-ECAEGRASCTFRCHNTA 528
+C+ +P C NG TC + + C C G+ +TC D +C E + C++
Sbjct: 670 DCSQNP--CHNGGTCRDLVNDFYCDCKNGWK---GKTCHSRDSQCDEATCNNGGTCYDEG 724
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG--SYICKCPEGYRRTSAP 586
+F+C CP G+ +G C P C + VV S+ C C EG+
Sbjct: 725 DAFKCMCPGGW----EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICA 780
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
Q++ N+C + G C++ D + C+C GF G DC
Sbjct: 781 QNT-------NDCSPHP-CYNSGTCVDGDNWYRCECAPGFA----GPDC 817
Score = 170 bits (414), Expect = 2e-41
Identities = 164/607 (27%), Positives = 253/607 (41%), Gaps = 84/607 (13%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCV 127
D+C P C G C++ +QC C+ + LC +D++ C +P C C
Sbjct: 263 DKCIPHPG-CVHGICNEP---WQCLCETNWG----GQLCDKDLNYCGTHQP-CLNGGTCS 313
Query: 128 NL-PGAFECRCPPGYRLTPSLDECEDVDE-CGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
N P ++C CP GY S CE + C + G C+ T + CEC PG+T
Sbjct: 314 NTGPDKYQCSCPEGY----SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWT-G 368
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVCR 244
++D+CS P GTC++L + C C + C +D NEC C
Sbjct: 369 PTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCPPQW---TGKTCQLDANECE--AKPCV 422
Query: 245 NGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS 303
N + C+N + S+ C+C PG+ G+NC D++ D L C D SC + GY C
Sbjct: 423 NAKSCKNLIASYYCDCLPGWM----GQNC-DININDCLGQ-CQNDA--SCRDLVNGYRCI 474
Query: 304 CGAGWKLVGRRCV-DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
C G+ G C D DEC P + GG C+N + C CP G+ + +C
Sbjct: 475 CPPGY--AGDHCERDIDECASNPCL-NGGHCQNEINRFQCLCPTGF----SGNLC----- 522
Query: 363 ELCYDEWEAGRCHRARPLQLARPE--CCCSEGAAWGRYC----ERCPAPDSAEFMRICQG 416
+L D E C + C C E G+ C + C E + C
Sbjct: 523 QLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE-GKNCSHLKDHC-RTTPCEVIDSCTV 580
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVN-TDGSFRCECPDGYVLAPDGLSC-VDADECA 473
M + + + + +VC G+C + + G F C+C G+ G C + ++C
Sbjct: 581 AMASNDTPEGVR--YISSNVCGPHGKCKSQSGGKFTCDCNKGFT----GTYCHENINDCE 634
Query: 474 LDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
+P C N GTC + Y+C CS G+ +T ++++C++ C + F
Sbjct: 635 SNP--CRNGGTCIDGVNSYKCICSDGWEGAYCET--NINDCSQNPCHNGGTCRDLVNDFY 690
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
C C G+ H RD +C + C + ++ C CP G+ T+ ++
Sbjct: 691 CDCKNGW--KGKTCHSRD-SQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSS 747
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP---SEDGTDCIDR---RTGTCYRS 646
C N C +GG C+ SF C C G+E +++ DC +GTC
Sbjct: 748 CLP-NPCH------NGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDG 800
Query: 647 LVSGRCE 653
RCE
Sbjct: 801 DNWYRCE 807
Score = 164 bits (399), Expect = 1e-39
Identities = 175/639 (27%), Positives = 262/639 (41%), Gaps = 115/639 (17%)
Query: 20 KYLCCCSVGHAWGAPCEA---------CPPRGSPAHTAL---CGEKPGEYINPVTNETKP 67
KY C C G++ G CE C RGS T+L C PG + P +
Sbjct: 319 KYQCSCPEGYS-GPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPG-WTGPTCSTN-- 374
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQ 125
ID+C P C G TC D GF+C C + T C+ D +EC PC
Sbjct: 375 IDDCS--PNNCSHGGTCQDLVNGFKCVCPPQW----TGKTCQLDANECE--AKPCVNAKS 426
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
C NL ++ C C PG+ C+ ++++C Q D CR+ + YRC C PGY
Sbjct: 427 CKNLIASYYCDCLPGWMG----QNCDININDCLGQCQND-ASCRDLVNGYRCICPPGYA- 480
Query: 185 RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVC 243
++ RD+DEC+ P G C+N + C C GF N C +D++ C C
Sbjct: 481 GDHCERDIDECAS-NPCLNGGHCQNEINRFQCLCPTGFSG---NLCQLDIDYCEPNP--C 534
Query: 244 RNG-RCRNTVGSFRCECAPGYTLTADGRNCRDV-DECDELPHPCGRDGNPSCTNTNGGYE 301
+NG +C N + C+C Y +G+NC + D C P C + SCT +
Sbjct: 535 QNGAQCYNRASDYFCKCPEDY----EGKNCSHLKDHCRTTP--C--EVIDSCTVAMASND 586
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGG-YVCECPAGWRFDKTAAVCVDE 360
G R + + C P+ G+C++ +GG + C+C G+ T C +
Sbjct: 587 TPEGV-------RYISSNVCG--PH----GKCKSQSGGKFTCDCNKGF----TGTYCHEN 629
Query: 361 RKELCYDEWEAGRCHRARPL--QLARPECCCSEGAAW-GRYCERCPAPDSAEFMRICQGG 417
++ E+ C + +C CS+G W G YCE D ++ C G
Sbjct: 630 -----INDCESNPCRNGGTCIDGVNSYKCICSDG--WEGAYCET-NINDCSQ--NPCHNG 679
Query: 418 MGRPNLTQDL----------DECRVRPDVCV------GGRCVNTDGSFRCECPDGYVLAP 461
+L D C R C GG C + +F+C CP G+
Sbjct: 680 GTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW---- 735
Query: 462 DGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRAS 519
+G +C A + P C NG TC + C C G+ +GP C + ++C+
Sbjct: 736 EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGW-EGP--ICAQNTNDCSPHPCY 792
Query: 520 CTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPE 578
+ C + +RC C G+A G CR +I+EC P C + + Y C CP
Sbjct: 793 NSGTCVDGDNWYRCECAPGFA----GPDCRININECQSSPCAFGATCVDEINGYRCVCPP 848
Query: 579 GYRRTSAPQDSENAC----EDINECEEQEDLCSGGVCIN 613
G+ + S C I + + +D C+ C+N
Sbjct: 849 GHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLN 887
Score = 163 bits (396), Expect = 2e-39
Identities = 158/579 (27%), Positives = 242/579 (41%), Gaps = 112/579 (19%)
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIG 172
C G P G + LPG +CRC G++ C D+C C HG C
Sbjct: 234 CRQGCSPKHGSCK---LPG--DCRCQYGWQGL----YC---DKCIPHPGCVHGICNEP-- 279
Query: 173 SYRCECKPGYTLRENVC-RDVDECSRPRPVCRNGTCENL-PGAYLCHCDDGFKAGPNNDC 230
++C C+ + +C +D++ C +P GTC N P Y C C +G+ +GPN +
Sbjct: 280 -WQCLCETNWG--GQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY-SGPNCEI 335
Query: 231 VDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRD 288
+ + C C N G C+ T F CEC+PG+T G C ++D+C P+ C
Sbjct: 336 AE-HACLSDP--CHNRGSCKETSLGFECECSPGWT----GPTCSTNIDDCS--PNNCSHG 386
Query: 289 GNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
G +C + G++C C W G+ C +D +EC+ P V A C+N Y C+C G
Sbjct: 387 G--TCQDLVNGFKCVCPPQW--TGKTCQLDANECEAKPCVNA-KSCKNLIASYYCDCLPG 441
Query: 348 W---RFDKTAAVCVD--ERKELCYDEWEAGRCHRARPLQLARPEC------CCSEGAAWG 396
W D C+ + C D RC P A C C S G
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVNGYRC--ICPPGYAGDHCERDIDECASNPCLNG 499
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQ-DLDECRVRPDVCV-GGRCVNTDGSFRCECP 454
+C+ + F +C G NL Q D+D C P+ C G +C N + C+CP
Sbjct: 500 GHCQN----EINRFQCLCPTGFS-GNLCQLDIDYC--EPNPCQNGAQCYNRASDYFCKCP 552
Query: 455 DGYVLAPDGLSCVD-ADECALDP-------------------------RICG-NGTCSNT 487
+ Y +G +C D C P +CG +G C +
Sbjct: 553 EDY----EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQ 608
Query: 488 RGG-YECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGV 546
GG + C C+ GFT ++++C C + S++C C G+ +G
Sbjct: 609 SGGKFTCDCNKGFT--GTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGW----EGA 662
Query: 547 HCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYR-RTSAPQDSENACEDINECEEQED 604
+C +I++C Q P C ++V + C C G++ +T +DS+ C++ C
Sbjct: 663 YCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ--CDEAT-CN---- 715
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
+GG C + +F C C G+E GT C R +C
Sbjct: 716 --NGGTCYDEGDAFKCMCPGGWE----GTTCNIARNSSC 748
Score = 120 bits (290), Expect = 2e-26
Identities = 90/320 (28%), Positives = 134/320 (41%), Gaps = 47/320 (14%)
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARP---------ECCCSEGAAW-GRYCERC-PAP 405
C + C + W C+RA Q P +C C G W G YC++C P P
Sbjct: 212 CDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYG--WQGLYCDKCIPHP 269
Query: 406 DSAE------FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTD-GSFRCECPDGYV 458
+ +C+ G +DL+ C GG C NT ++C CP+GY
Sbjct: 270 GCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY- 328
Query: 459 LAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGR 517
G +C A+ L G+C T G+EC+CSPG+T GP TC ++D+C+
Sbjct: 329 ---SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWT-GP--TCSTNIDDCSPNN 382
Query: 518 ASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKC 576
S C + F+C CP + G C+ D +EC +P V +C+N++ SY C C
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKSCKNLIASYYCDC 438
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLCDCDAGFEPSEDGTDC 635
G+ +N +IN+C Q C C + + C C G+ D
Sbjct: 439 LPGWM-------GQNCDININDCLGQ---CQNDASCRDLVNGYRCICPPGYAGDHCERDI 488
Query: 636 IDRRTGTCYRSLVSGRCEPE 655
+ + C L G C+ E
Sbjct: 489 DECASNPC---LNGGHCQNE 505
Score = 64.5 bits (150), Expect = 2e-09
Identities = 35/92 (38%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
+RC+C PGY AG+ C D+DECA P C N + CLC TG+ G C+
Sbjct: 471 YRCICPPGY--AGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGF----SGNLCQL 524
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
D+D CE + C N Y C C + YE
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE 556
Score = 56.8 bits (131), Expect = 3e-07
Identities = 55/215 (25%), Positives = 89/215 (41%), Gaps = 36/215 (16%)
Query: 74 MPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNLPG 131
+P C GTC F C C G+E +C ++ ++CS PC CV+
Sbjct: 749 LPNPCHNGGTCVVNGESFTCVCKEGWE----GPICAQNTNDCS--PHPCYNSGTCVDGDN 802
Query: 132 AFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR 190
+ C C PG+ + +C +++EC C + I YRC C PG++ + C+
Sbjct: 803 WYRCECAPGF----AGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAK--CQ 856
Query: 191 DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRN 250
+V RP G+ +P DG K ++DC + +C G + C C
Sbjct: 857 EVS----GRPCITMGSV--IP--------DGAKW--DDDC-NTCQCLNGRIACSKVWC-- 897
Query: 251 TVGSFRCECAPGYTLTADGRNCRDVDECDELPHPC 285
G C G++ G++C + + HPC
Sbjct: 898 --GPRPCLLHKGHSECPSGQSCIPILDDQCFVHPC 930
Score = 46.8 bits (106), Expect = 3e-04
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 761 GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G+F C C G+ G C + +++C P C + SY C+C G+E GA C
Sbjct: 611 GKFTCDCNKGF--TGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWE----GAYC 664
Query: 820 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
++++C ++ C + + C C++G+ +G C
Sbjct: 665 ETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGW--KGKTC 702
Score = 46.4 bits (105), Expect = 4e-04
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F CVC G+ G +CA + ++C+ P C + D Y C C G+ G +CR
Sbjct: 766 FTCVCKEGWE--GPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFA----GPDCRI 819
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
+++EC+ C + Y C C G+
Sbjct: 820 NINECQSSPCAFGATCVDEINGYRCVCPPGH 850
Score = 45.2 bits (102), Expect = 0.001
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F C C PG+ G C+ ++D+C+ C + + C+C + G C+
Sbjct: 358 FECECSPGW--TGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQL 411
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
D +ECE + C N SY C C G+
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDCLPGW 442
Score = 45.2 bits (102), Expect = 0.001
Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 17/120 (14%)
Query: 747 DVDECAAIPGLCAPG------RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D +EC A P + A + C C PG+ G+ C ++++C + D C +
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDCLPGWM--GQNCDININDCLGQCQN-DASCRDLV 468
Query: 800 GSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
Y C+C GY G +C RD+DEC + C N ++C C G+ G+ C
Sbjct: 469 NGYRCICPPGYA----GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFS--GNLC 522
Score = 45.2 bits (102), Expect = 0.001
Identities = 28/120 (23%), Positives = 54/120 (45%), Gaps = 16/120 (13%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
++++C + P G C G ++C+C G+ G C ++++C+ P C +
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWE--GAYCETNINDCSQNPCHNGGTCRDLV 686
Query: 800 GSYDCLCRTGYELDEDGANCRDVD-ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
+ C C+ G++ G C D +C+ T C + +++C C G+E G C
Sbjct: 687 NDFYCDCKNGWK----GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE--GTTC 740
Score = 39.5 bits (88), Expect = 0.050
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 13/94 (13%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC- 819
F+C+C G+ G C + P PC C S+ C+C+ G+E G C
Sbjct: 727 FKCMCPGGWE--GTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE----GPICA 780
Query: 820 RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
++ ++C H C C + + Y C C G+
Sbjct: 781 QNTNDC--SPHPCYNSGTCVDGDNWYRCECAPGF 812
Score = 39.5 bits (88), Expect = 0.050
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 9/70 (12%)
Query: 756 GLCAPGR--FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G C G +RC C PG+ AG C +++EC P C + Y C+C G+
Sbjct: 795 GTCVDGDNWYRCECAPGF--AGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGH-- 850
Query: 813 DEDGANCRDV 822
GA C++V
Sbjct: 851 --SGAKCQEV 858
Score = 35.5 bits (78), Expect = 0.81
Identities = 35/107 (32%), Positives = 46/107 (42%), Gaps = 22/107 (20%)
Query: 751 CAAIPGLCA-PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C+ G C PG RC Y G C D+C P +C+ + CLC T
Sbjct: 238 CSPKHGSCKLPGDCRCQ----YGWQGLYC---DKCIPHPGCVHGICNEP---WQCLCETN 287
Query: 810 YELDEDGANC-RDVDECERDTHT-CQQ--ICSNT-EGSYECSCEDGY 851
+ G C +D++ C TH C CSNT Y+CSC +GY
Sbjct: 288 W----GGQLCDKDLNYC--GTHQPCLNGGTCSNTGPDKYQCSCPEGY 328
>AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein.
Length = 1218
Score = 202 bits (492), Expect = 6e-51
Identities = 174/649 (26%), Positives = 271/649 (41%), Gaps = 88/649 (13%)
Query: 8 QSCAGAVGVPQTKYLCCCSVGHAW-GAPCEACPPRGSPAHTALCGEKPGEYINPVTNE-- 64
Q C+ G + C C G W G C+ C P H +C E P + + TN
Sbjct: 236 QGCSPKHGSCKLPGDCRCQYG--WQGLYCDKCIPHPGCVH-GICNE-PWQCLCE-TNWGG 290
Query: 65 ---TKPIDECDIMPQLCKPGTCHDT-PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
K ++ C GTC +T P +QC C GY N C ++ E + PC
Sbjct: 291 QLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPN----C-EIAEHACLSDPC 345
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
C FEC C PG+ P+ ++D+C G C++ + ++C C P
Sbjct: 346 HNRGSCKETSLGFECECSPGWT-GPTCST--NIDDCSPNNCSHGGTCQDLVNGFKCVCPP 402
Query: 181 GYTLRENVCR-DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREG 239
+T + C+ D +EC +P +C+NL +Y C C G+ G N D +++N+C
Sbjct: 403 QWTGK--TCQLDANECEA-KPCVNAKSCKNLIASYYCDCLPGWM-GQNCD-ININDCL-- 455
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNG 298
G + CR+ V +RC C PGY G +C RD+DEC +PC G+ C N
Sbjct: 456 GQCQNDASCRDLVNGYRCICPPGYA----GDHCERDIDECAS--NPCLDGGH--CQNEIN 507
Query: 299 GYECSCGAGWKLVGRRC-VDRDECKELPYVCAGG-ECRNFNGGYVCECPAGWRFDKTAAV 356
++C C G+ G C +D D C+ P C G +C N Y C+CP + + +
Sbjct: 508 RFQCLCPTGFS--GNLCQLDIDYCEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHL 563
Query: 357 CVDERKELC--YDEWEAGRCHRARP--LQLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
R C D P ++ C G +C + +F
Sbjct: 564 KDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHG--------KCKSQSGGKFTC 615
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDAD 470
C G +++++C P C GG C++ S++C C DG+ +G C + +
Sbjct: 616 DCNKGFTGTYCHENINDCESNP--CRNGGTCIDGVNSYKCICSDGW----EGAYCETNIN 669
Query: 471 ECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVD-ECAEGRASCTFRCHNTA 528
+C+ +P C NG TC + + C C G+ +TC D +C E + C++
Sbjct: 670 DCSQNP--CHNGGTCRDLVNDFYCDCKNGWK---GKTCHSRDSQCDEATCNNGGTCYDEG 724
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG--SYICKCPEGYRRTSAP 586
+F+C CP G+ +G C P C + VV S+ C C EG+
Sbjct: 725 DAFKCMCPGGW----EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICA 780
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
Q++ N+C + G C++ D + C+C GF G DC
Sbjct: 781 QNT-------NDCSPHP-CYNSGTCVDGDNWYRCECAPGFA----GPDC 817
Score = 170 bits (414), Expect = 2e-41
Identities = 164/607 (27%), Positives = 253/607 (41%), Gaps = 84/607 (13%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCV 127
D+C P C G C++ +QC C+ + LC +D++ C +P C C
Sbjct: 263 DKCIPHPG-CVHGICNEP---WQCLCETNWG----GQLCDKDLNYCGTHQP-CLNGGTCS 313
Query: 128 NL-PGAFECRCPPGYRLTPSLDECEDVDE-CGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
N P ++C CP GY S CE + C + G C+ T + CEC PG+T
Sbjct: 314 NTGPDKYQCSCPEGY----SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWT-G 368
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVCR 244
++D+CS P GTC++L + C C + C +D NEC C
Sbjct: 369 PTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCPPQW---TGKTCQLDANECE--AKPCV 422
Query: 245 NGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS 303
N + C+N + S+ C+C PG+ G+NC D++ D L C D SC + GY C
Sbjct: 423 NAKSCKNLIASYYCDCLPGWM----GQNC-DININDCLGQ-CQNDA--SCRDLVNGYRCI 474
Query: 304 CGAGWKLVGRRCV-DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
C G+ G C D DEC P + GG C+N + C CP G+ + +C
Sbjct: 475 CPPGY--AGDHCERDIDECASNPCL-DGGHCQNEINRFQCLCPTGF----SGNLC----- 522
Query: 363 ELCYDEWEAGRCHRARPLQLARPE--CCCSEGAAWGRYC----ERCPAPDSAEFMRICQG 416
+L D E C + C C E G+ C + C E + C
Sbjct: 523 QLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE-GKNCSHLKDHC-RTTPCEVIDSCTV 580
Query: 417 GMGRPNLTQDLDECRVRPDVC-VGGRCVN-TDGSFRCECPDGYVLAPDGLSC-VDADECA 473
M + + + + +VC G+C + + G F C+C G+ G C + ++C
Sbjct: 581 AMASNDTPEGVR--YISSNVCGPHGKCKSQSGGKFTCDCNKGFT----GTYCHENINDCE 634
Query: 474 LDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
+P C N GTC + Y+C CS G+ +T ++++C++ C + F
Sbjct: 635 SNP--CRNGGTCIDGVNSYKCICSDGWEGAYCET--NINDCSQNPCHNGGTCRDLVNDFY 690
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
C C G+ H RD +C + C + ++ C CP G+ T+ ++
Sbjct: 691 CDCKNGW--KGKTCHSRD-SQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSS 747
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP---SEDGTDCIDR---RTGTCYRS 646
C N C +GG C+ SF C C G+E +++ DC +GTC
Sbjct: 748 CLP-NPCH------NGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDG 800
Query: 647 LVSGRCE 653
RCE
Sbjct: 801 DNWYRCE 807
Score = 163 bits (397), Expect = 2e-39
Identities = 175/639 (27%), Positives = 262/639 (41%), Gaps = 115/639 (17%)
Query: 20 KYLCCCSVGHAWGAPCEA---------CPPRGSPAHTAL---CGEKPGEYINPVTNETKP 67
KY C C G++ G CE C RGS T+L C PG + P +
Sbjct: 319 KYQCSCPEGYS-GPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPG-WTGPTCSTN-- 374
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQ 125
ID+C P C G TC D GF+C C + T C+ D +EC PC
Sbjct: 375 IDDCS--PNNCSHGGTCQDLVNGFKCVCPPQW----TGKTCQLDANECE--AKPCVNAKS 426
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
C NL ++ C C PG+ C+ ++++C Q D CR+ + YRC C PGY
Sbjct: 427 CKNLIASYYCDCLPGWMG----QNCDININDCLGQCQND-ASCRDLVNGYRCICPPGYA- 480
Query: 185 RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGGMVC 243
++ RD+DEC+ P G C+N + C C GF N C +D++ C C
Sbjct: 481 GDHCERDIDECAS-NPCLDGGHCQNEINRFQCLCPTGFSG---NLCQLDIDYCEPNP--C 534
Query: 244 RNG-RCRNTVGSFRCECAPGYTLTADGRNCRDV-DECDELPHPCGRDGNPSCTNTNGGYE 301
+NG +C N + C+C Y +G+NC + D C P C + SCT +
Sbjct: 535 QNGAQCYNRASDYFCKCPEDY----EGKNCSHLKDHCRTTP--C--EVIDSCTVAMASND 586
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGG-YVCECPAGWRFDKTAAVCVDE 360
G R + + C P+ G+C++ +GG + C+C G+ T C +
Sbjct: 587 TPEGV-------RYISSNVCG--PH----GKCKSQSGGKFTCDCNKGF----TGTYCHEN 629
Query: 361 RKELCYDEWEAGRCHRARPL--QLARPECCCSEGAAW-GRYCERCPAPDSAEFMRICQGG 417
++ E+ C + +C CS+G W G YCE D ++ C G
Sbjct: 630 -----INDCESNPCRNGGTCIDGVNSYKCICSDG--WEGAYCET-NINDCSQ--NPCHNG 679
Query: 418 MGRPNLTQDL----------DECRVRPDVCV------GGRCVNTDGSFRCECPDGYVLAP 461
+L D C R C GG C + +F+C CP G+
Sbjct: 680 GTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW---- 735
Query: 462 DGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRAS 519
+G +C A + P C NG TC + C C G+ +GP C + ++C+
Sbjct: 736 EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGW-EGP--ICAQNTNDCSPHPCY 792
Query: 520 CTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPE 578
+ C + +RC C G+A G CR +I+EC P C + + Y C CP
Sbjct: 793 NSGTCVDGDNWYRCECAPGFA----GPDCRININECQSSPCAFGATCVDEINGYRCVCPP 848
Query: 579 GYRRTSAPQDSENAC----EDINECEEQEDLCSGGVCIN 613
G+ + S C I + + +D C+ C+N
Sbjct: 849 GHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLN 887
Score = 163 bits (396), Expect = 2e-39
Identities = 158/579 (27%), Positives = 242/579 (41%), Gaps = 112/579 (19%)
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIG 172
C G P G + LPG +CRC G++ C D+C C HG C
Sbjct: 234 CRQGCSPKHGSCK---LPG--DCRCQYGWQGL----YC---DKCIPHPGCVHGICNEP-- 279
Query: 173 SYRCECKPGYTLRENVC-RDVDECSRPRPVCRNGTCENL-PGAYLCHCDDGFKAGPNNDC 230
++C C+ + +C +D++ C +P GTC N P Y C C +G+ +GPN +
Sbjct: 280 -WQCLCETNWG--GQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY-SGPNCEI 335
Query: 231 VDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRD 288
+ + C C N G C+ T F CEC+PG+T G C ++D+C P+ C
Sbjct: 336 AE-HACLSDP--CHNRGSCKETSLGFECECSPGWT----GPTCSTNIDDCS--PNNCSHG 386
Query: 289 GNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
G +C + G++C C W G+ C +D +EC+ P V A C+N Y C+C G
Sbjct: 387 G--TCQDLVNGFKCVCPPQW--TGKTCQLDANECEAKPCVNA-KSCKNLIASYYCDCLPG 441
Query: 348 W---RFDKTAAVCVD--ERKELCYDEWEAGRCHRARPLQLARPEC------CCSEGAAWG 396
W D C+ + C D RC P A C C S G
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVNGYRC--ICPPGYAGDHCERDIDECASNPCLDG 499
Query: 397 RYCERCPAPDSAEFMRICQGGMGRPNLTQ-DLDECRVRPDVCV-GGRCVNTDGSFRCECP 454
+C+ + F +C G NL Q D+D C P+ C G +C N + C+CP
Sbjct: 500 GHCQN----EINRFQCLCPTGFS-GNLCQLDIDYC--EPNPCQNGAQCYNRASDYFCKCP 552
Query: 455 DGYVLAPDGLSCVD-ADECALDP-------------------------RICG-NGTCSNT 487
+ Y +G +C D C P +CG +G C +
Sbjct: 553 EDY----EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQ 608
Query: 488 RGG-YECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGV 546
GG + C C+ GFT ++++C C + S++C C G+ +G
Sbjct: 609 SGGKFTCDCNKGFT--GTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGW----EGA 662
Query: 547 HCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYR-RTSAPQDSENACEDINECEEQED 604
+C +I++C Q P C ++V + C C G++ +T +DS+ C++ C
Sbjct: 663 YCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ--CDEAT-CN---- 715
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
+GG C + +F C C G+E GT C R +C
Sbjct: 716 --NGGTCYDEGDAFKCMCPGGWE----GTTCNIARNSSC 748
Score = 120 bits (290), Expect = 2e-26
Identities = 90/320 (28%), Positives = 134/320 (41%), Gaps = 47/320 (14%)
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARP---------ECCCSEGAAW-GRYCERC-PAP 405
C + C + W C+RA Q P +C C G W G YC++C P P
Sbjct: 212 CDQNGNKTCMEGWMGRECNRAICRQGCSPKHGSCKLPGDCRCQYG--WQGLYCDKCIPHP 269
Query: 406 DSAE------FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTD-GSFRCECPDGYV 458
+ +C+ G +DL+ C GG C NT ++C CP+GY
Sbjct: 270 GCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY- 328
Query: 459 LAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGR 517
G +C A+ L G+C T G+EC+CSPG+T GP TC ++D+C+
Sbjct: 329 ---SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWT-GP--TCSTNIDDCSPNN 382
Query: 518 ASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKC 576
S C + F+C CP + G C+ D +EC +P V +C+N++ SY C C
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKSCKNLIASYYCDC 438
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLCDCDAGFEPSEDGTDC 635
G+ +N +IN+C Q C C + + C C G+ D
Sbjct: 439 LPGWM-------GQNCDININDCLGQ---CQNDASCRDLVNGYRCICPPGYAGDHCERDI 488
Query: 636 IDRRTGTCYRSLVSGRCEPE 655
+ + C L G C+ E
Sbjct: 489 DECASNPC---LDGGHCQNE 505
Score = 111 bits (266), Expect = 1e-23
Identities = 119/428 (27%), Positives = 168/428 (39%), Gaps = 65/428 (15%)
Query: 233 VNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPH-PCGRDGNP 291
+N R+ + +N + R C Y + CR D D H C ++GN
Sbjct: 161 INPSRQWQTLKQNTGVAHFEYQIRVTCDDYYYGFGCNKFCRPRD--DFFGHYACDQNGNK 218
Query: 292 SCTNTNGGYECS---CGAG-------WKLVGR-RC------VDRDECKELPYVCAGGECR 334
+C G EC+ C G KL G RC + D+C P C G C
Sbjct: 219 TCMEGWMGRECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHP-GCVHGIC- 276
Query: 335 NFNGGYVCECPAGW---RFDKTAAVCVDERKEL---CYDEWEAGRCHRARPLQLARPECC 388
N + C C W DK C + L + + P + P C
Sbjct: 277 --NEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCE 334
Query: 389 CSEGAAWGRYCERCPA--PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNT 445
+E A C + S F C G P + ++D+C P+ C GG C +
Sbjct: 335 IAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDC--SPNNCSHGGTCQDL 392
Query: 446 DGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGP 503
F+C CP + G +C +DA+EC P C N +C N Y C C PG+
Sbjct: 393 VNGFKCVCPPQWT----GKTCQLDANECEAKP--CVNAKSCKNLIASYYCDCLPGWM--- 443
Query: 504 DQTC-VDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVC 561
Q C +++++C G+ C + +RC CP GYA G HC RDIDEC P +
Sbjct: 444 GQNCDININDCL-GQCQNDASCRDLVNGYRCICPPGYA----GDHCERDIDECASNPCLD 498
Query: 562 PHACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGV-CINTDGSFL 619
C+N + + C CP G+ S N C+ DI+ CE C G C N +
Sbjct: 499 GGHCQNEINRFQCLCPTGF--------SGNLCQLDIDYCEPNP--CQNGAQCYNRASDYF 548
Query: 620 CDCDAGFE 627
C C +E
Sbjct: 549 CKCPEDYE 556
Score = 64.5 bits (150), Expect = 2e-09
Identities = 35/92 (38%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
+RC+C PGY AG+ C D+DECA P C N + CLC TG+ G C+
Sbjct: 471 YRCICPPGY--AGDHCERDIDECASNPCLDGGHCQNEINRFQCLCPTGF----SGNLCQL 524
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
D+D CE + C N Y C C + YE
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE 556
Score = 56.8 bits (131), Expect = 3e-07
Identities = 55/215 (25%), Positives = 89/215 (41%), Gaps = 36/215 (16%)
Query: 74 MPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNLPG 131
+P C GTC F C C G+E +C ++ ++CS PC CV+
Sbjct: 749 LPNPCHNGGTCVVNGESFTCVCKEGWE----GPICAQNTNDCS--PHPCYNSGTCVDGDN 802
Query: 132 AFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR 190
+ C C PG+ + +C +++EC C + I YRC C PG++ + C+
Sbjct: 803 WYRCECAPGF----AGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAK--CQ 856
Query: 191 DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRN 250
+V RP G+ +P DG K ++DC + +C G + C C
Sbjct: 857 EVS----GRPCITMGSV--IP--------DGAKW--DDDC-NTCQCLNGRIACSKVWC-- 897
Query: 251 TVGSFRCECAPGYTLTADGRNCRDVDECDELPHPC 285
G C G++ G++C + + HPC
Sbjct: 898 --GPRPCLLHKGHSECPSGQSCIPILDDQCFVHPC 930
Score = 46.8 bits (106), Expect = 3e-04
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 761 GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G+F C C G+ G C + +++C P C + SY C+C G+E GA C
Sbjct: 611 GKFTCDCNKGF--TGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWE----GAYC 664
Query: 820 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
++++C ++ C + + C C++G+ +G C
Sbjct: 665 ETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGW--KGKTC 702
Score = 46.4 bits (105), Expect = 4e-04
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F CVC G+ G +CA + ++C+ P C + D Y C C G+ G +CR
Sbjct: 766 FTCVCKEGWE--GPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFA----GPDCRI 819
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
+++EC+ C + Y C C G+
Sbjct: 820 NINECQSSPCAFGATCVDEINGYRCVCPPGH 850
Score = 45.2 bits (102), Expect = 0.001
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F C C PG+ G C+ ++D+C+ C + + C+C + G C+
Sbjct: 358 FECECSPGW--TGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQL 411
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
D +ECE + C N SY C C G+
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDCLPGW 442
Score = 45.2 bits (102), Expect = 0.001
Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 17/120 (14%)
Query: 747 DVDECAAIPGLCAPG------RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D +EC A P + A + C C PG+ G+ C ++++C + D C +
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDCLPGWM--GQNCDININDCLGQCQN-DASCRDLV 468
Query: 800 GSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
Y C+C GY G +C RD+DEC + C N ++C C G+ G+ C
Sbjct: 469 NGYRCICPPGYA----GDHCERDIDECASNPCLDGGHCQNEINRFQCLCPTGFS--GNLC 522
Score = 45.2 bits (102), Expect = 0.001
Identities = 28/120 (23%), Positives = 54/120 (45%), Gaps = 16/120 (13%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
++++C + P G C G ++C+C G+ G C ++++C+ P C +
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWE--GAYCETNINDCSQNPCHNGGTCRDLV 686
Query: 800 GSYDCLCRTGYELDEDGANCRDVD-ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
+ C C+ G++ G C D +C+ T C + +++C C G+E G C
Sbjct: 687 NDFYCDCKNGWK----GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE--GTTC 740
Score = 39.5 bits (88), Expect = 0.050
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 13/94 (13%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC- 819
F+C+C G+ G C + P PC C S+ C+C+ G+E G C
Sbjct: 727 FKCMCPGGWE--GTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE----GPICA 780
Query: 820 RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
++ ++C H C C + + Y C C G+
Sbjct: 781 QNTNDC--SPHPCYNSGTCVDGDNWYRCECAPGF 812
Score = 39.5 bits (88), Expect = 0.050
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 9/70 (12%)
Query: 756 GLCAPGR--FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G C G +RC C PG+ AG C +++EC P C + Y C+C G+
Sbjct: 795 GTCVDGDNWYRCECAPGF--AGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGH-- 850
Query: 813 DEDGANCRDV 822
GA C++V
Sbjct: 851 --SGAKCQEV 858
Score = 35.5 bits (78), Expect = 0.81
Identities = 35/107 (32%), Positives = 46/107 (42%), Gaps = 22/107 (20%)
Query: 751 CAAIPGLCA-PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C+ G C PG RC Y G C D+C P +C+ + CLC T
Sbjct: 238 CSPKHGSCKLPGDCRCQ----YGWQGLYC---DKCIPHPGCVHGICNEP---WQCLCETN 287
Query: 810 YELDEDGANC-RDVDECERDTHT-CQQ--ICSNT-EGSYECSCEDGY 851
+ G C +D++ C TH C CSNT Y+CSC +GY
Sbjct: 288 W----GGQLCDKDLNYC--GTHQPCLNGGTCSNTGPDKYQCSCPEGY 328
>AK131552-1|BAD18686.1| 682|Homo sapiens protein ( Homo sapiens
cDNA FLJ16792 fis, clone TBAES2007379, moderately
similar to Homo sapiens signal peptide, CUB domain,
EGF-like 2 (SCUBE2). ).
Length = 682
Score = 197 bits (481), Expect = 1e-49
Identities = 136/422 (32%), Positives = 180/422 (42%), Gaps = 37/422 (8%)
Query: 191 DVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE---GGMVCRNG 246
DVDEC++ C + C+N P +Y C C G++ G C D++EC GG V
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ-GEGRQCEDIDECGNELNGGCV---H 100
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
C N G++RC C G+ L DG NC DVDEC E C +C N G YEC C
Sbjct: 101 DCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH----TCVNVMGSYECCCKE 156
Query: 307 GWKLVGRR--CVDRDE----CKELPYVCAGGECRNF-NGGYVCECPAGWRFDKTAAVCVD 359
G+ L + C+ R E C + C+ C+ G CEC G+ K C+
Sbjct: 157 GFFLSDNQHTCIHRSEEGLSCMNKDHGCSH-ICKEAPRGSVACECRPGFELAKNQRDCI- 214
Query: 360 ERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAW---GRYC-ERCPAPDSAEFMRICQ 415
L + G C + PEC C GR C ER
Sbjct: 215 ----LTCNHGNGG-CQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTS 269
Query: 416 GGMGRPNLTQDL--DECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
G + + L + C V C C +T C CP G+ L DG +C D DEC
Sbjct: 270 VVDGDKRVKRQLLMETCAVNNGGC-DRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQ 328
Query: 474 LDPRICGNGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCTFRCHNTAGSFR 532
C + C N G ++C C GF D+ +C DVDEC+ R +C C N G+F
Sbjct: 329 TRNGGCDH-FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDR-TCDHSCINHPGTFA 386
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
C C GY + HC D +EC C C N VGSY C+C GY+ +D +
Sbjct: 387 CACNRGYTLYGF-THCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVAS 445
Query: 593 CE 594
C+
Sbjct: 446 CD 447
Score = 194 bits (473), Expect = 1e-48
Identities = 139/436 (31%), Positives = 185/436 (42%), Gaps = 49/436 (11%)
Query: 221 GFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC- 278
G AGP D V+EC +G C + C+NT S++C C PGY +GR C D+DEC
Sbjct: 37 GRAAGPQED---VDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECG 91
Query: 279 DELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNF 336
+EL C D C N G Y C+C G+ L G C+D DEC E C C N
Sbjct: 92 NELNGGCVHD----CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNV 146
Query: 337 NGGYVCECPAGWRFDKTAAVCVDERKE--LCYDEWEAGRCHRARPLQLARPECCCSEGAA 394
G Y C C G+ C+ +E C ++ + G H + C C G
Sbjct: 147 MGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNK-DHGCSHICKEAPRGSVACECRPGFE 205
Query: 395 WGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDV-CVGGRCVNTDGSFRCEC 453
+ C + C G G D+ P+ C ++TDG E
Sbjct: 206 LAKNQRDC--------ILTCNHGNG--GCQHSCDDTADGPECSCHPQYKMHTDGRSCLER 255
Query: 454 PDGY--VLAPDGLSCVDADE----------CALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
D V + S VD D+ CA++ C TC +T G C C GFT
Sbjct: 256 EDTVLEVTESNTTSVVDGDKRVKRQLLMETCAVNNGGCDR-TCKDTSTGVHCSCPVGFTL 314
Query: 502 GPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRV 560
D +TC D+DEC C C N GSF C C G+ + D C+D+DEC + R
Sbjct: 315 QLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLD-RT 373
Query: 561 CPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC 620
C H+C N G++ C C GY C D NEC C VC+NT GS+ C
Sbjct: 374 CDHSCINHPGTFACACNRGYTLYGFTH-----CGDTNECSINNGGCQ-QVCVNTVGSYEC 427
Query: 621 DCDAGFEPSEDGTDCI 636
C G++ + DC+
Sbjct: 428 QCHPGYKLHWNKKDCV 443
Score = 149 bits (362), Expect = 3e-35
Identities = 123/410 (30%), Positives = 175/410 (42%), Gaps = 62/410 (15%)
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRI--CDHGD 166
DVDEC+ G C A C N P +++C C PGY+ +CED+DECG++ C H D
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNELNGGCVH-D 101
Query: 167 CRNTIGSYRCECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA 224
C N G+YRC C G+ L + C DVDEC C++ TC N+ G+Y C C +GF
Sbjct: 102 CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFL 160
Query: 225 GPN-NDCVDVNE----CREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECD 279
N + C+ +E C C + GS CEC PG+ L + R+C + C+
Sbjct: 161 SDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDC--ILTCN 218
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDEC---------------- 321
C SC +T G ECSC +K+ GR C++R++
Sbjct: 219 HGNGGC----QHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGD 274
Query: 322 -----KELPYVCA---GG---ECRNFNGGYVCECPAGWRFDKTAAVC--VDERK------ 362
+ L CA GG C++ + G C CP G+ C +DE +
Sbjct: 275 KRVKRQLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGC 334
Query: 363 -ELCYDEWEAGRCHRARPLQLARPECCCS--EGAAWGRYCERCPAPDSAEFMRICQGGMG 419
C + + C + +L E C + + R C+ F C G
Sbjct: 335 DHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCINHPGTFACACNRGYT 394
Query: 420 RPNLTQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
T D +EC + C CVNT GS+ C+C GY L + CV
Sbjct: 395 LYGFTHCGDTNECSINNGGC-QQVCVNTVGSYECQCHPGYKLHWNKKDCV 443
Score = 134 bits (323), Expect = 2e-30
Identities = 103/332 (31%), Positives = 144/332 (43%), Gaps = 49/332 (14%)
Query: 68 IDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ- 125
+DEC C C +TPT ++C C GY+ + C D+DEC G G
Sbjct: 46 VDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ--CEDIDEC--GNELNGGCVHD 101
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRI-CDHGDCRNTIGSYRCECKPGYTL 184
C+N+PG + C C G+ L C DVDEC + C H C N +GSY C CK G+ L
Sbjct: 102 CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFL 160
Query: 185 REN--VCRDVDE----CSRPRPVCRNGTCENLP-GAYLCHCDDGFKAGPN-NDCVDVNEC 236
+N C E C C + C+ P G+ C C GF+ N DC + C
Sbjct: 161 SDNQHTCIHRSEEGLSCMNKDHGCSH-ICKEAPRGSVACECRPGFELAKNQRDC--ILTC 217
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRD----VDECDE------------ 280
G C++ C +T C C P Y + DGR+C + V E E
Sbjct: 218 NHGNGGCQHS-CDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKR 276
Query: 281 -----LPHPCGRDG---NPSCTNTNGGYECSCGAGW--KLVGRRCVDRDECKELPYVCAG 330
L C + + +C +T+ G CSC G+ +L G+ C D DEC+ C
Sbjct: 277 VKRQLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGC-D 335
Query: 331 GECRNFNGGYVCECPAGWRF--DKTAAVCVDE 360
C+N G + C C G++ D+ + VDE
Sbjct: 336 HFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDE 367
Score = 123 bits (297), Expect = 2e-27
Identities = 88/269 (32%), Positives = 113/269 (42%), Gaps = 20/269 (7%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGY 141
TC DT TG C C G+ C+D+DEC C C N+ G+F+C C G+
Sbjct: 296 TCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHF--CKNIVGSFDCGCKKGF 353
Query: 142 RLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE-NVCRDVDECSRPRP 200
+L C+DVDEC R CDH C N G++ C C GYTL C D +ECS
Sbjct: 354 KLLTDEKSCQDVDECSLDRTCDH-SCINHPGTFACACNRGYTLYGFTHCGDTNECSINNG 412
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCR-NGRCRNTVGSFR-C 257
C+ C N G+Y C C G+K N DC V C +V R R R + + R
Sbjct: 413 GCQQ-VCVNTVGSYECQCHPGYKLHWNKKDC--VASCDLSCIVKRTEKRLRKAIRTLRKA 469
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVD 317
+ L G N +D + P R SC G E C + R
Sbjct: 470 VHREQFHLQLSGMN---LDVAKKPPRTSERQAE-SCGVGQGHAENQC-----VSCRAGTY 520
Query: 318 RDECKELPYVCAGGECRNFNGGYVCE-CP 345
D +E +C G +N G CE CP
Sbjct: 521 YDGARERCILCPNGTFQNEEGQMTCEPCP 549
Score = 112 bits (270), Expect = 4e-24
Identities = 77/255 (30%), Positives = 99/255 (38%), Gaps = 17/255 (6%)
Query: 392 GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ-DLDECRVRPDVC-VGGRCVNTDGSF 449
GAAW P G GR Q D+DEC D C C NT S+
Sbjct: 10 GAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSY 69
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCV 508
+C C GY +G C D DEC + C N G Y C C GF D C+
Sbjct: 70 KCSCKPGY--QGEGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCL 127
Query: 509 DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDE----CVQEPRVCPHA 564
DVDEC E C C N GS+ C C G+ ++ + C E C+ + C H
Sbjct: 128 DVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHI 187
Query: 565 CENVV-GSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCD 623
C+ GS C+C G+ +D C I C C C +T C C
Sbjct: 188 CKEAPRGSVACECRPGFELAKNQRD----C--ILTCNHGNGGCQHS-CDDTADGPECSCH 240
Query: 624 AGFEPSEDGTDCIDR 638
++ DG C++R
Sbjct: 241 PQYKMHTDGRSCLER 255
Score = 100 bits (240), Expect = 2e-20
Identities = 49/114 (42%), Positives = 59/114 (51%), Gaps = 9/114 (7%)
Query: 747 DVDECAA------IPGLC--APGRFRCVCGPGYRPAGEVCADVDECAVR-PPPCDQLCHN 797
DVDECA LC P ++C C PGY+ G C D+DEC C C N
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHDCLN 104
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G+Y C C G+ L DG NC DVDEC + CQ C N GSYEC C++G+
Sbjct: 105 IPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGF 158
Score = 89.8 bits (213), Expect = 4e-17
Identities = 39/93 (41%), Positives = 52/93 (55%), Gaps = 3/93 (3%)
Query: 765 CVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDV 822
C C G+ + G+ C D+DEC R CD C N GS+DC C+ G++L D +C+DV
Sbjct: 306 CSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDV 365
Query: 823 DECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
DEC D TC C N G++ C+C GY G
Sbjct: 366 DECSLD-RTCDHSCINHPGTFACACNRGYTLYG 397
Score = 87.4 bits (207), Expect = 2e-16
Identities = 45/114 (39%), Positives = 58/114 (50%), Gaps = 10/114 (8%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNT 798
D+DEC G C G F C C G++ + C DVDEC++ CD C N
Sbjct: 323 DIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSL-DRTCDHSCINH 381
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
G++ C C GY L +C D +EC + CQQ+C NT GSYEC C GY+
Sbjct: 382 PGTFACACNRGYTL-YGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYK 434
Score = 78.2 bits (184), Expect = 1e-13
Identities = 43/120 (35%), Positives = 53/120 (44%), Gaps = 14/120 (11%)
Query: 747 DVDECA-AIPGLCA------PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
D+DEC + G C PG +RC C G+ A G C DVDEC C C N
Sbjct: 86 DIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVN 145
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDE----CERDTHTCQQICSNT-EGSYECSCEDGYE 852
GSY+C C+ G+ L ++ C E C H C IC GS C C G+E
Sbjct: 146 VMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFE 205
Score = 72.9 bits (171), Expect = 4e-12
Identities = 26/72 (36%), Positives = 39/72 (54%)
Query: 781 VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTE 840
++ CAV CD+ C +T C C G+ L DG C+D+DEC+ C C N
Sbjct: 283 METCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIV 342
Query: 841 GSYECSCEDGYE 852
GS++C C+ G++
Sbjct: 343 GSFDCGCKKGFK 354
Score = 64.5 bits (150), Expect = 2e-09
Identities = 32/79 (40%), Positives = 41/79 (51%), Gaps = 6/79 (7%)
Query: 747 DVDECA---AIPGLCA--PGRFRCVCGPGYRPAGEV-CADVDECAVRPPPCDQLCHNTDG 800
DVDEC+ C PG F C C GY G C D +EC++ C Q+C NT G
Sbjct: 364 DVDECSLDRTCDHSCINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVG 423
Query: 801 SYDCLCRTGYELDEDGANC 819
SY+C C GY+L + +C
Sbjct: 424 SYECQCHPGYKLHWNKKDC 442
Score = 52.8 bits (121), Expect = 5e-06
Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 15/123 (12%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGE--VCADVDE----CAVRPPPCDQL 794
DVDEC G C G + C C G+ + C E C + C +
Sbjct: 128 DVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHI 187
Query: 795 CHNTD-GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C GS C CR G+EL ++ +C + C CQ C +T ECSC Y+
Sbjct: 188 CKEAPRGSVACECRPGFELAKNQRDC--ILTCNHGNGGCQHSCDDTADGPECSCHPQYKM 245
Query: 854 RGD 856
D
Sbjct: 246 HTD 248
Score = 44.0 bits (99), Expect = 0.002
Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 2/40 (5%)
Query: 821 DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
DVDEC + C +C NT SY+CSC+ GY+ G C
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQC 84
Score = 35.1 bits (77), Expect = 1.1
Identities = 18/74 (24%), Positives = 29/74 (39%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
C+ I G C C PG+ A + C C C +T +C C Y
Sbjct: 184 CSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGGCQHSCDDTADGPECSCHPQY 243
Query: 811 ELDEDGANCRDVDE 824
++ DG +C + ++
Sbjct: 244 KMHTDGRSCLERED 257
>BC111690-1|AAI11691.1| 807|Homo sapiens SCUBE2 protein protein.
Length = 807
Score = 197 bits (480), Expect = 2e-49
Identities = 135/422 (31%), Positives = 179/422 (42%), Gaps = 37/422 (8%)
Query: 191 DVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE---GGMVCRNG 246
DVDEC++ C + C+N P +Y C C G++ G C D++EC GG V
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ-GEGRQCEDIDECGNELNGGCV---H 100
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
C N G++RC C G+ L DG NC DVDEC E C +C N G YEC C
Sbjct: 101 DCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH----TCVNVMGSYECCCKE 156
Query: 307 GWKLVGRR--CVDRDE----CKELPYVCAGGECRNF-NGGYVCECPAGWRFDKTAAVCVD 359
G+ L + C+ R E C + C+ C+ G CEC G+ K C+
Sbjct: 157 GFFLSDNQHTCIHRSEEGLSCMNKDHGCSH-ICKEAPRGSVACECRPGFELAKNQRDCI- 214
Query: 360 ERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAW---GRYC---ERCPAPDSAEFMRI 413
L + G C + PEC C GR C E +
Sbjct: 215 ----LTCNHGNGG-CQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTS 269
Query: 414 CQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
G R ++ C V C C +T C CP G+ L DG +C D DEC
Sbjct: 270 VVDGDKRVKRRLLMETCAVNNGGC-DRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQ 328
Query: 474 LDPRICGNGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCTFRCHNTAGSFR 532
C + C N G ++C C GF D+ +C DVDEC+ R +C C N G+F
Sbjct: 329 TRNGGCDH-FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDR-TCDHSCINHPGTFA 386
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENA 592
C C GY + HC D +EC C C N VGSY C+C GY+ +D +
Sbjct: 387 CACNRGYTLYGF-THCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVAS 445
Query: 593 CE 594
C+
Sbjct: 446 CD 447
Score = 194 bits (473), Expect = 1e-48
Identities = 139/436 (31%), Positives = 185/436 (42%), Gaps = 49/436 (11%)
Query: 221 GFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC- 278
G AGP D V+EC +G C + C+NT S++C C PGY +GR C D+DEC
Sbjct: 37 GRAAGPQED---VDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECG 91
Query: 279 DELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNF 336
+EL C D C N G Y C+C G+ L G C+D DEC E C C N
Sbjct: 92 NELNGGCVHD----CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNV 146
Query: 337 NGGYVCECPAGWRFDKTAAVCVDERKE--LCYDEWEAGRCHRARPLQLARPECCCSEGAA 394
G Y C C G+ C+ +E C ++ + G H + C C G
Sbjct: 147 MGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNK-DHGCSHICKEAPRGSVACECRPGFE 205
Query: 395 WGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDV-CVGGRCVNTDGSFRCEC 453
+ C + C G G D+ P+ C ++TDG E
Sbjct: 206 LAKNQRDC--------ILTCNHGNG--GCQHSCDDTADGPECSCHPQYKMHTDGRSCLER 255
Query: 454 PDGY--VLAPDGLSCVDADE----------CALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
D V + S VD D+ CA++ C TC +T G C C GFT
Sbjct: 256 EDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDR-TCKDTSTGVHCSCPVGFTL 314
Query: 502 GPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRV 560
D +TC D+DEC C C N GSF C C G+ + D C+D+DEC + R
Sbjct: 315 QLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLD-RT 373
Query: 561 CPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC 620
C H+C N G++ C C GY C D NEC C VC+NT GS+ C
Sbjct: 374 CDHSCINHPGTFACACNRGYTLYGFTH-----CGDTNECSINNGGCQ-QVCVNTVGSYEC 427
Query: 621 DCDAGFEPSEDGTDCI 636
C G++ + DC+
Sbjct: 428 QCHPGYKLHWNKKDCV 443
Score = 150 bits (363), Expect = 2e-35
Identities = 123/410 (30%), Positives = 175/410 (42%), Gaps = 62/410 (15%)
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRI--CDHGD 166
DVDEC+ G C A C N P +++C C PGY+ +CED+DECG++ C H D
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNELNGGCVH-D 101
Query: 167 CRNTIGSYRCECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA 224
C N G+YRC C G+ L + C DVDEC C++ TC N+ G+Y C C +GF
Sbjct: 102 CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFL 160
Query: 225 GPN-NDCVDVNE----CREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECD 279
N + C+ +E C C + GS CEC PG+ L + R+C + C+
Sbjct: 161 SDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDC--ILTCN 218
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDEC---------------- 321
C SC +T G ECSC +K+ GR C++R++
Sbjct: 219 HGNGGC----QHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGD 274
Query: 322 -----KELPYVCA---GG---ECRNFNGGYVCECPAGWRFDKTAAVC--VDERK------ 362
+ L CA GG C++ + G C CP G+ C +DE +
Sbjct: 275 KRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGC 334
Query: 363 -ELCYDEWEAGRCHRARPLQLARPECCCS--EGAAWGRYCERCPAPDSAEFMRICQGGMG 419
C + + C + +L E C + + R C+ F C G
Sbjct: 335 DHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCINHPGTFACACNRGYT 394
Query: 420 RPNLTQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV 467
T D +EC + C CVNT GS+ C+C GY L + CV
Sbjct: 395 LYGFTHCGDTNECSINNGGC-QQVCVNTVGSYECQCHPGYKLHWNKKDCV 443
Score = 134 bits (323), Expect = 2e-30
Identities = 103/332 (31%), Positives = 144/332 (43%), Gaps = 49/332 (14%)
Query: 68 IDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ- 125
+DEC C C +TPT ++C C GY+ + C D+DEC G G
Sbjct: 46 VDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ--CEDIDEC--GNELNGGCVHD 101
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRI-CDHGDCRNTIGSYRCECKPGYTL 184
C+N+PG + C C G+ L C DVDEC + C H C N +GSY C CK G+ L
Sbjct: 102 CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFL 160
Query: 185 REN--VCRDVDE----CSRPRPVCRNGTCENLP-GAYLCHCDDGFKAGPN-NDCVDVNEC 236
+N C E C C + C+ P G+ C C GF+ N DC + C
Sbjct: 161 SDNQHTCIHRSEEGLSCMNKDHGCSH-ICKEAPRGSVACECRPGFELAKNQRDC--ILTC 217
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRD----VDECDE------------ 280
G C++ C +T C C P Y + DGR+C + V E E
Sbjct: 218 NHGNGGCQHS-CDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKR 276
Query: 281 -----LPHPCGRDG---NPSCTNTNGGYECSCGAGW--KLVGRRCVDRDECKELPYVCAG 330
L C + + +C +T+ G CSC G+ +L G+ C D DEC+ C
Sbjct: 277 VKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGC-D 335
Query: 331 GECRNFNGGYVCECPAGWRF--DKTAAVCVDE 360
C+N G + C C G++ D+ + VDE
Sbjct: 336 HFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDE 367
Score = 123 bits (297), Expect = 2e-27
Identities = 88/269 (32%), Positives = 113/269 (42%), Gaps = 20/269 (7%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGY 141
TC DT TG C C G+ C+D+DEC C C N+ G+F+C C G+
Sbjct: 296 TCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHF--CKNIVGSFDCGCKKGF 353
Query: 142 RLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE-NVCRDVDECSRPRP 200
+L C+DVDEC R CDH C N G++ C C GYTL C D +ECS
Sbjct: 354 KLLTDEKSCQDVDECSLDRTCDH-SCINHPGTFACACNRGYTLYGFTHCGDTNECSINNG 412
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCR-NGRCRNTVGSFR-C 257
C+ C N G+Y C C G+K N DC V C +V R R R + + R
Sbjct: 413 GCQQ-VCVNTVGSYECQCHPGYKLHWNKKDC--VASCDLSCIVKRTEKRLRKAIRTLRKA 469
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVD 317
+ L G N +D + P R SC G E C + R
Sbjct: 470 VHREQFHLQLSGMN---LDVAKKPPRTSERQAE-SCGVGQGHAENQC-----VSCRAGTY 520
Query: 318 RDECKELPYVCAGGECRNFNGGYVCE-CP 345
D +E +C G +N G CE CP
Sbjct: 521 YDGARERCILCPNGTFQNEEGQMTCEPCP 549
Score = 112 bits (270), Expect = 4e-24
Identities = 77/255 (30%), Positives = 99/255 (38%), Gaps = 17/255 (6%)
Query: 392 GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ-DLDECRVRPDVC-VGGRCVNTDGSF 449
GAAW P G GR Q D+DEC D C C NT S+
Sbjct: 10 GAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSY 69
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCV 508
+C C GY +G C D DEC + C N G Y C C GF D C+
Sbjct: 70 KCSCKPGY--QGEGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCL 127
Query: 509 DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDE----CVQEPRVCPHA 564
DVDEC E C C N GS+ C C G+ ++ + C E C+ + C H
Sbjct: 128 DVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHI 187
Query: 565 CENVV-GSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCD 623
C+ GS C+C G+ +D C I C C C +T C C
Sbjct: 188 CKEAPRGSVACECRPGFELAKNQRD----C--ILTCNHGNGGCQHS-CDDTADGPECSCH 240
Query: 624 AGFEPSEDGTDCIDR 638
++ DG C++R
Sbjct: 241 PQYKMHTDGRSCLER 255
Score = 100 bits (240), Expect = 2e-20
Identities = 49/114 (42%), Positives = 59/114 (51%), Gaps = 9/114 (7%)
Query: 747 DVDECAA------IPGLC--APGRFRCVCGPGYRPAGEVCADVDECAVR-PPPCDQLCHN 797
DVDECA LC P ++C C PGY+ G C D+DEC C C N
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHDCLN 104
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G+Y C C G+ L DG NC DVDEC + CQ C N GSYEC C++G+
Sbjct: 105 IPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGF 158
Score = 89.8 bits (213), Expect = 4e-17
Identities = 39/93 (41%), Positives = 52/93 (55%), Gaps = 3/93 (3%)
Query: 765 CVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDV 822
C C G+ + G+ C D+DEC R CD C N GS+DC C+ G++L D +C+DV
Sbjct: 306 CSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDV 365
Query: 823 DECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
DEC D TC C N G++ C+C GY G
Sbjct: 366 DECSLD-RTCDHSCINHPGTFACACNRGYTLYG 397
Score = 87.4 bits (207), Expect = 2e-16
Identities = 45/114 (39%), Positives = 58/114 (50%), Gaps = 10/114 (8%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNT 798
D+DEC G C G F C C G++ + C DVDEC++ CD C N
Sbjct: 323 DIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSL-DRTCDHSCINH 381
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
G++ C C GY L +C D +EC + CQQ+C NT GSYEC C GY+
Sbjct: 382 PGTFACACNRGYTL-YGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYK 434
Score = 78.2 bits (184), Expect = 1e-13
Identities = 43/120 (35%), Positives = 53/120 (44%), Gaps = 14/120 (11%)
Query: 747 DVDECA-AIPGLCA------PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
D+DEC + G C PG +RC C G+ A G C DVDEC C C N
Sbjct: 86 DIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVN 145
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDE----CERDTHTCQQICSNT-EGSYECSCEDGYE 852
GSY+C C+ G+ L ++ C E C H C IC GS C C G+E
Sbjct: 146 VMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFE 205
Score = 72.9 bits (171), Expect = 4e-12
Identities = 26/72 (36%), Positives = 39/72 (54%)
Query: 781 VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTE 840
++ CAV CD+ C +T C C G+ L DG C+D+DEC+ C C N
Sbjct: 283 METCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIV 342
Query: 841 GSYECSCEDGYE 852
GS++C C+ G++
Sbjct: 343 GSFDCGCKKGFK 354
Score = 64.5 bits (150), Expect = 2e-09
Identities = 32/79 (40%), Positives = 41/79 (51%), Gaps = 6/79 (7%)
Query: 747 DVDECA---AIPGLCA--PGRFRCVCGPGYRPAGEV-CADVDECAVRPPPCDQLCHNTDG 800
DVDEC+ C PG F C C GY G C D +EC++ C Q+C NT G
Sbjct: 364 DVDECSLDRTCDHSCINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVG 423
Query: 801 SYDCLCRTGYELDEDGANC 819
SY+C C GY+L + +C
Sbjct: 424 SYECQCHPGYKLHWNKKDC 442
Score = 52.8 bits (121), Expect = 5e-06
Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 15/123 (12%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGE--VCADVDE----CAVRPPPCDQL 794
DVDEC G C G + C C G+ + C E C + C +
Sbjct: 128 DVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHI 187
Query: 795 CHNTD-GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C GS C CR G+EL ++ +C + C CQ C +T ECSC Y+
Sbjct: 188 CKEAPRGSVACECRPGFELAKNQRDC--ILTCNHGNGGCQHSCDDTADGPECSCHPQYKM 245
Query: 854 RGD 856
D
Sbjct: 246 HTD 248
Score = 44.0 bits (99), Expect = 0.002
Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 2/40 (5%)
Query: 821 DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
DVDEC + C +C NT SY+CSC+ GY+ G C
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQC 84
Score = 35.1 bits (77), Expect = 1.1
Identities = 18/74 (24%), Positives = 29/74 (39%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
C+ I G C C PG+ A + C C C +T +C C Y
Sbjct: 184 CSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGGCQHSCDDTADGPECSCHPQY 243
Query: 811 ELDEDGANCRDVDE 824
++ DG +C + ++
Sbjct: 244 KMHTDGRSCLERED 257
>AK123039-1|BAC85521.1| 971|Homo sapiens protein ( Homo sapiens
cDNA FLJ41044 fis, clone NT2RP7000466, highly similar
to Mus musculus CUB domain and EGF-like repeat
containing 1 (Cegf1). ).
Length = 971
Score = 195 bits (475), Expect = 6e-49
Identities = 139/437 (31%), Positives = 186/437 (42%), Gaps = 49/437 (11%)
Query: 221 GFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC- 278
G AGP D V+EC +G C + C+NT S++C C PGY +GR C D+DEC
Sbjct: 37 GRAAGPQED---VDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECG 91
Query: 279 DELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNF 336
+EL C D C N G Y C+C G+ L G C+D DEC E C C N
Sbjct: 92 NELNGGCVHD----CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNV 146
Query: 337 NGGYVCECPAGWRFDKTAAVCVDERKE--LCYDEWEAGRCHRARPLQLARPECCCSEGAA 394
G Y C C G+ C+ +E C ++ + G H + C C G
Sbjct: 147 MGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNK-DHGCSHICKEAPRGSVACECRPGFE 205
Query: 395 WGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDV-CVGGRCVNTDGSFRCEC 453
+ C + C G G D+ P+ C ++TDG E
Sbjct: 206 LAKNQRDC--------ILTCNHGNG--GCQHSCDDTADGPECSCHPQYKMHTDGRSCLER 255
Query: 454 PDGY--VLAPDGLSCVDADE----------CALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
D V + S VD D+ CA++ C TC +T G C C GFT
Sbjct: 256 EDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDR-TCKDTSTGVHCSCPVGFTL 314
Query: 502 GPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRV 560
D +TC D+DEC C C N GSF C C G+ + D C+D+DEC + R
Sbjct: 315 QLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLD-RT 373
Query: 561 CPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC 620
C H+C N G++ C C GY C D NEC C VC+NT GS+ C
Sbjct: 374 CDHSCINHPGTFACACNRGYTLYGFTH-----CGDTNECSINNGGCQ-QVCVNTVGSYEC 427
Query: 621 DCDAGFEPSEDGTDCID 637
C G++ + DC++
Sbjct: 428 QCHPGYKLHWNKKDCVE 444
Score = 184 bits (449), Expect = 9e-46
Identities = 135/452 (29%), Positives = 185/452 (40%), Gaps = 25/452 (5%)
Query: 151 EDVDECGDQRICDHGD--CRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCE 208
EDVDEC H D C+NT SY+C CKPGY C D+DEC C
Sbjct: 44 EDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHDCL 103
Query: 209 NLPGAYLCHCDDGFK-AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTA 267
N+PG Y C C DGF A ++C+DV+EC E C++ C N +GS+ C C G+ L+
Sbjct: 104 NIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFLSD 162
Query: 268 DGRNCRDVDE----CDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKE 323
+ C E C H C + G C C G++L + C
Sbjct: 163 NQHTCIHRSEEGLSCMNKDHGCSHICKEA---PRGSVACECRPGFELAKNQRDCILTCNH 219
Query: 324 LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLA 383
C C + G C C ++ C+ ER++ + E+ +
Sbjct: 220 GNGGCQHS-CDDTADGPECSCHPQYKMHTDGRSCL-EREDTVLEVTESNTTSVVDGDKRV 277
Query: 384 RPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRP---NLTQDLDECRVRPDVCVGG 440
+ A C+R S C G +D+DEC+ R C
Sbjct: 278 KRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGC-DH 336
Query: 441 RCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT 500
C N GSF C C G+ L D SC D DEC+LD R C + +C N G + C C+ G+T
Sbjct: 337 FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLD-RTCDH-SCINHPGTFACACNRGYT 394
Query: 501 QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ---E 557
C D +EC+ C C NT GS+ C C GY + + C ++ +
Sbjct: 395 LYGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVEVKGLLPTSVS 454
Query: 558 PRVCPHACENVVGSYIC--KCPEGYRRTSAPQ 587
PRV H C G C +C G +S Q
Sbjct: 455 PRVSLH-CGKSGGGDGCFLRCHSGIHLSSGLQ 485
Score = 153 bits (372), Expect = 2e-36
Identities = 131/446 (29%), Positives = 190/446 (42%), Gaps = 69/446 (15%)
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRI--CDHGD 166
DVDEC+ G C A C N P +++C C PGY+ +CED+DECG++ C H D
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNELNGGCVH-D 101
Query: 167 CRNTIGSYRCECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA 224
C N G+YRC C G+ L + C DVDEC C++ TC N+ G+Y C C +GF
Sbjct: 102 CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFL 160
Query: 225 GPN-NDCVDVNE----CREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECD 279
N + C+ +E C C + GS CEC PG+ L + R+C + C+
Sbjct: 161 SDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDC--ILTCN 218
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDEC---------------- 321
C SC +T G ECSC +K+ GR C++R++
Sbjct: 219 HGNGGC----QHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGD 274
Query: 322 -----KELPYVCA---GG---ECRNFNGGYVCECPAGWRFDKTAAVC--VDERK------ 362
+ L CA GG C++ + G C CP G+ C +DE +
Sbjct: 275 KRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGC 334
Query: 363 -ELCYDEWEAGRCHRARPLQLARPECCCS--EGAAWGRYCERCPAPDSAEFMRICQGGMG 419
C + + C + +L E C + + R C+ F C G
Sbjct: 335 DHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCINHPGTFACACNRGYT 394
Query: 420 RPNLTQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDAD---ECAL 474
T D +EC + C CVNT GS+ C+C GY L + CV+ ++
Sbjct: 395 LYGFTHCGDTNECSINNGGC-QQVCVNTVGSYECQCHPGYKLHWNKKDCVEVKGLLPTSV 453
Query: 475 DPRICGNGTCSNTRGGYEC--QCSPG 498
PR+ + C + GG C +C G
Sbjct: 454 SPRVSLH--CGKSGGGDGCFLRCHSG 477
Score = 122 bits (294), Expect = 5e-27
Identities = 61/154 (39%), Positives = 77/154 (50%), Gaps = 6/154 (3%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGY 141
TC DT TG C C G+ C+D+DEC C C N+ G+F+C C G+
Sbjct: 296 TCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHF--CKNIVGSFDCGCKKGF 353
Query: 142 RLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE-NVCRDVDECSRPRP 200
+L C+DVDEC R CDH C N G++ C C GYTL C D +ECS
Sbjct: 354 KLLTDEKSCQDVDECSLDRTCDH-SCINHPGTFACACNRGYTLYGFTHCGDTNECSINNG 412
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDV 233
C+ C N G+Y C C G+K N DCV+V
Sbjct: 413 GCQQ-VCVNTVGSYECQCHPGYKLHWNKKDCVEV 445
Score = 112 bits (270), Expect = 4e-24
Identities = 77/255 (30%), Positives = 99/255 (38%), Gaps = 17/255 (6%)
Query: 392 GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ-DLDECRVRPDVC-VGGRCVNTDGSF 449
GAAW P G GR Q D+DEC D C C NT S+
Sbjct: 10 GAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSY 69
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCV 508
+C C GY +G C D DEC + C N G Y C C GF D C+
Sbjct: 70 KCSCKPGY--QGEGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCL 127
Query: 509 DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDE----CVQEPRVCPHA 564
DVDEC E C C N GS+ C C G+ ++ + C E C+ + C H
Sbjct: 128 DVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHI 187
Query: 565 CENVV-GSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCD 623
C+ GS C+C G+ +D C I C C C +T C C
Sbjct: 188 CKEAPRGSVACECRPGFELAKNQRD----C--ILTCNHGNGGCQHS-CDDTADGPECSCH 240
Query: 624 AGFEPSEDGTDCIDR 638
++ DG C++R
Sbjct: 241 PQYKMHTDGRSCLER 255
Score = 100 bits (240), Expect = 2e-20
Identities = 49/114 (42%), Positives = 59/114 (51%), Gaps = 9/114 (7%)
Query: 747 DVDECAA------IPGLC--APGRFRCVCGPGYRPAGEVCADVDECAVR-PPPCDQLCHN 797
DVDECA LC P ++C C PGY+ G C D+DEC C C N
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHDCLN 104
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G+Y C C G+ L DG NC DVDEC + CQ C N GSYEC C++G+
Sbjct: 105 IPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGF 158
Score = 89.8 bits (213), Expect = 4e-17
Identities = 39/93 (41%), Positives = 52/93 (55%), Gaps = 3/93 (3%)
Query: 765 CVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDV 822
C C G+ + G+ C D+DEC R CD C N GS+DC C+ G++L D +C+DV
Sbjct: 306 CSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDV 365
Query: 823 DECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
DEC D TC C N G++ C+C GY G
Sbjct: 366 DECSLD-RTCDHSCINHPGTFACACNRGYTLYG 397
Score = 87.4 bits (207), Expect = 2e-16
Identities = 45/114 (39%), Positives = 58/114 (50%), Gaps = 10/114 (8%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNT 798
D+DEC G C G F C C G++ + C DVDEC++ CD C N
Sbjct: 323 DIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSL-DRTCDHSCINH 381
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
G++ C C GY L +C D +EC + CQQ+C NT GSYEC C GY+
Sbjct: 382 PGTFACACNRGYTL-YGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYK 434
Score = 78.2 bits (184), Expect = 1e-13
Identities = 43/120 (35%), Positives = 53/120 (44%), Gaps = 14/120 (11%)
Query: 747 DVDECA-AIPGLCA------PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
D+DEC + G C PG +RC C G+ A G C DVDEC C C N
Sbjct: 86 DIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVN 145
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDE----CERDTHTCQQICSNT-EGSYECSCEDGYE 852
GSY+C C+ G+ L ++ C E C H C IC GS C C G+E
Sbjct: 146 VMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFE 205
Score = 72.9 bits (171), Expect = 4e-12
Identities = 26/72 (36%), Positives = 39/72 (54%)
Query: 781 VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTE 840
++ CAV CD+ C +T C C G+ L DG C+D+DEC+ C C N
Sbjct: 283 METCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIV 342
Query: 841 GSYECSCEDGYE 852
GS++C C+ G++
Sbjct: 343 GSFDCGCKKGFK 354
Score = 65.7 bits (153), Expect = 7e-10
Identities = 33/82 (40%), Positives = 43/82 (52%), Gaps = 6/82 (7%)
Query: 747 DVDECA---AIPGLCA--PGRFRCVCGPGYRPAGEV-CADVDECAVRPPPCDQLCHNTDG 800
DVDEC+ C PG F C C GY G C D +EC++ C Q+C NT G
Sbjct: 364 DVDECSLDRTCDHSCINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVG 423
Query: 801 SYDCLCRTGYELDEDGANCRDV 822
SY+C C GY+L + +C +V
Sbjct: 424 SYECQCHPGYKLHWNKKDCVEV 445
Score = 52.8 bits (121), Expect = 5e-06
Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 15/123 (12%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGE--VCADVDE----CAVRPPPCDQL 794
DVDEC G C G + C C G+ + C E C + C +
Sbjct: 128 DVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHI 187
Query: 795 CHNTD-GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C GS C CR G+EL ++ +C + C CQ C +T ECSC Y+
Sbjct: 188 CKEAPRGSVACECRPGFELAKNQRDC--ILTCNHGNGGCQHSCDDTADGPECSCHPQYKM 245
Query: 854 RGD 856
D
Sbjct: 246 HTD 248
Score = 44.0 bits (99), Expect = 0.002
Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 2/40 (5%)
Query: 821 DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
DVDEC + C +C NT SY+CSC+ GY+ G C
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQC 84
Score = 35.1 bits (77), Expect = 1.1
Identities = 18/74 (24%), Positives = 29/74 (39%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
C+ I G C C PG+ A + C C C +T +C C Y
Sbjct: 184 CSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGGCQHSCDDTADGPECSCHPQY 243
Query: 811 ELDEDGANCRDVDE 824
++ DG +C + ++
Sbjct: 244 KMHTDGRSCLERED 257
>AJ400877-1|CAB92285.1| 999|Homo sapiens CEGP1 protein protein.
Length = 999
Score = 195 bits (475), Expect = 6e-49
Identities = 139/437 (31%), Positives = 186/437 (42%), Gaps = 49/437 (11%)
Query: 221 GFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC- 278
G AGP D V+EC +G C + C+NT S++C C PGY +GR C D+DEC
Sbjct: 37 GRAAGPQED---VDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECG 91
Query: 279 DELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNF 336
+EL C D C N G Y C+C G+ L G C+D DEC E C C N
Sbjct: 92 NELNGGCVHD----CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNV 146
Query: 337 NGGYVCECPAGWRFDKTAAVCVDERKE--LCYDEWEAGRCHRARPLQLARPECCCSEGAA 394
G Y C C G+ C+ +E C ++ + G H + C C G
Sbjct: 147 MGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNK-DHGCSHICKEAPRGSVACECRPGFE 205
Query: 395 WGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDV-CVGGRCVNTDGSFRCEC 453
+ C + C G G D+ P+ C ++TDG E
Sbjct: 206 LAKNQRDC--------ILTCNHGNG--GCQHSCDDTADGPECSCHPQYKMHTDGRSCLER 255
Query: 454 PDGY--VLAPDGLSCVDADE----------CALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
D V + S VD D+ CA++ C TC +T G C C GFT
Sbjct: 256 EDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDR-TCKDTSTGVHCSCPVGFTL 314
Query: 502 GPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRV 560
D +TC D+DEC C C N GSF C C G+ + D C+D+DEC + R
Sbjct: 315 QLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLD-RT 373
Query: 561 CPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC 620
C H+C N G++ C C GY C D NEC C VC+NT GS+ C
Sbjct: 374 CDHSCINHPGTFACACNRGYTLYGFTH-----CGDTNECSINNGGCQ-QVCVNTVGSYEC 427
Query: 621 DCDAGFEPSEDGTDCID 637
C G++ + DC++
Sbjct: 428 QCHPGYKLHWNKKDCVE 444
Score = 184 bits (447), Expect = 2e-45
Identities = 134/449 (29%), Positives = 184/449 (40%), Gaps = 25/449 (5%)
Query: 151 EDVDECGDQRICDHGD--CRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCE 208
EDVDEC H D C+NT SY+C CKPGY C D+DEC C
Sbjct: 44 EDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHDCL 103
Query: 209 NLPGAYLCHCDDGFK-AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTA 267
N+PG Y C C DGF A ++C+DV+EC E C++ C N +GS+ C C G+ L+
Sbjct: 104 NIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFLSD 162
Query: 268 DGRNCRDVDE----CDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKE 323
+ C E C H C + G C C G++L + C
Sbjct: 163 NQHTCIHRSEEGLSCMNKDHGCSHICKEA---PRGSVACECRPGFELAKNQRDCILTCNH 219
Query: 324 LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLA 383
C C + G C C ++ C+ ER++ + E+ +
Sbjct: 220 GNGGCQHS-CDDTADGPECSCHPQYKMHTDGRSCL-EREDTVLEVTESNTTSVVDGDKRV 277
Query: 384 RPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRP---NLTQDLDECRVRPDVCVGG 440
+ A C+R S C G +D+DEC+ R C
Sbjct: 278 KRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGC-DH 336
Query: 441 RCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT 500
C N GSF C C G+ L D SC D DEC+LD R C + +C N G + C C+ G+T
Sbjct: 337 FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLD-RTCDH-SCINHPGTFACACNRGYT 394
Query: 501 QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ---E 557
C D +EC+ C C NT GS+ C C GY + + C ++ +
Sbjct: 395 LYGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVEVKGLLPTSVS 454
Query: 558 PRVCPHACENVVGSYIC--KCPEGYRRTS 584
PRV H C G C +C G +S
Sbjct: 455 PRVSLH-CGKSGGGDGCFLRCHSGIHLSS 482
Score = 156 bits (378), Expect = 4e-37
Identities = 133/456 (29%), Positives = 193/456 (42%), Gaps = 69/456 (15%)
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRI--CDHGD 166
DVDEC+ G C A C N P +++C C PGY+ +CED+DECG++ C H D
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNELNGGCVH-D 101
Query: 167 CRNTIGSYRCECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA 224
C N G+YRC C G+ L + C DVDEC C++ TC N+ G+Y C C +GF
Sbjct: 102 CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFL 160
Query: 225 GPN-NDCVDVNE----CREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECD 279
N + C+ +E C C + GS CEC PG+ L + R+C + C+
Sbjct: 161 SDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDC--ILTCN 218
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDEC---------------- 321
C SC +T G ECSC +K+ GR C++R++
Sbjct: 219 HGNGGC----QHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGD 274
Query: 322 -----KELPYVCA---GG---ECRNFNGGYVCECPAGWRFDKTAAVC--VDERK------ 362
+ L CA GG C++ + G C CP G+ C +DE +
Sbjct: 275 KRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGC 334
Query: 363 -ELCYDEWEAGRCHRARPLQLARPECCCS--EGAAWGRYCERCPAPDSAEFMRICQGGMG 419
C + + C + +L E C + + R C+ F C G
Sbjct: 335 DHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCINHPGTFACACNRGYT 394
Query: 420 RPNLTQ--DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDAD---ECAL 474
T D +EC + C CVNT GS+ C+C GY L + CV+ ++
Sbjct: 395 LYGFTHCGDTNECSINNGGC-QQVCVNTVGSYECQCHPGYKLHWNKKDCVEVKGLLPTSV 453
Query: 475 DPRICGNGTCSNTRGGYEC--QCSPGFTQGPDQTCV 508
PR+ + C + GG C +C G D T +
Sbjct: 454 SPRVSLH--CGKSGGGDGCFLRCHSGIHLSSDVTTI 487
Score = 123 bits (296), Expect = 3e-27
Identities = 69/192 (35%), Positives = 90/192 (46%), Gaps = 9/192 (4%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGY 141
TC DT TG C C G+ C+D+DEC C C N+ G+F+C C G+
Sbjct: 296 TCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHF--CKNIVGSFDCGCKKGF 353
Query: 142 RLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE-NVCRDVDECSRPRP 200
+L C+DVDEC R CDH C N G++ C C GYTL C D +ECS
Sbjct: 354 KLLTDEKSCQDVDECSLDRTCDH-SCINHPGTFACACNRGYTLYGFTHCGDTNECSINNG 412
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCR-NGRCRNTVGSFRC- 257
C+ C N G+Y C C G+K N DCV+V + R + C + G C
Sbjct: 413 GCQQ-VCVNTVGSYECQCHPGYKLHWNKKDCVEVKGLLPTSVSPRVSLHCGKSGGGDGCF 471
Query: 258 -ECAPGYTLTAD 268
C G L++D
Sbjct: 472 LRCHSGIHLSSD 483
Score = 112 bits (270), Expect = 4e-24
Identities = 77/255 (30%), Positives = 99/255 (38%), Gaps = 17/255 (6%)
Query: 392 GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ-DLDECRVRPDVC-VGGRCVNTDGSF 449
GAAW P G GR Q D+DEC D C C NT S+
Sbjct: 10 GAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSY 69
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCV 508
+C C GY +G C D DEC + C N G Y C C GF D C+
Sbjct: 70 KCSCKPGY--QGEGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCL 127
Query: 509 DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDE----CVQEPRVCPHA 564
DVDEC E C C N GS+ C C G+ ++ + C E C+ + C H
Sbjct: 128 DVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHI 187
Query: 565 CENVV-GSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCD 623
C+ GS C+C G+ +D C I C C C +T C C
Sbjct: 188 CKEAPRGSVACECRPGFELAKNQRD----C--ILTCNHGNGGCQHS-CDDTADGPECSCH 240
Query: 624 AGFEPSEDGTDCIDR 638
++ DG C++R
Sbjct: 241 PQYKMHTDGRSCLER 255
Score = 100 bits (240), Expect = 2e-20
Identities = 49/114 (42%), Positives = 59/114 (51%), Gaps = 9/114 (7%)
Query: 747 DVDECAA------IPGLC--APGRFRCVCGPGYRPAGEVCADVDECAVR-PPPCDQLCHN 797
DVDECA LC P ++C C PGY+ G C D+DEC C C N
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHDCLN 104
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G+Y C C G+ L DG NC DVDEC + CQ C N GSYEC C++G+
Sbjct: 105 IPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGF 158
Score = 89.8 bits (213), Expect = 4e-17
Identities = 39/93 (41%), Positives = 52/93 (55%), Gaps = 3/93 (3%)
Query: 765 CVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDV 822
C C G+ + G+ C D+DEC R CD C N GS+DC C+ G++L D +C+DV
Sbjct: 306 CSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDV 365
Query: 823 DECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
DEC D TC C N G++ C+C GY G
Sbjct: 366 DECSLD-RTCDHSCINHPGTFACACNRGYTLYG 397
Score = 87.4 bits (207), Expect = 2e-16
Identities = 45/114 (39%), Positives = 58/114 (50%), Gaps = 10/114 (8%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNT 798
D+DEC G C G F C C G++ + C DVDEC++ CD C N
Sbjct: 323 DIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSL-DRTCDHSCINH 381
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
G++ C C GY L +C D +EC + CQQ+C NT GSYEC C GY+
Sbjct: 382 PGTFACACNRGYTL-YGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYK 434
Score = 78.2 bits (184), Expect = 1e-13
Identities = 43/120 (35%), Positives = 53/120 (44%), Gaps = 14/120 (11%)
Query: 747 DVDECA-AIPGLCA------PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHN 797
D+DEC + G C PG +RC C G+ A G C DVDEC C C N
Sbjct: 86 DIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVN 145
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDE----CERDTHTCQQICSNT-EGSYECSCEDGYE 852
GSY+C C+ G+ L ++ C E C H C IC GS C C G+E
Sbjct: 146 VMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFE 205
Score = 72.9 bits (171), Expect = 4e-12
Identities = 26/72 (36%), Positives = 39/72 (54%)
Query: 781 VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTE 840
++ CAV CD+ C +T C C G+ L DG C+D+DEC+ C C N
Sbjct: 283 METCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIV 342
Query: 841 GSYECSCEDGYE 852
GS++C C+ G++
Sbjct: 343 GSFDCGCKKGFK 354
Score = 65.7 bits (153), Expect = 7e-10
Identities = 33/82 (40%), Positives = 43/82 (52%), Gaps = 6/82 (7%)
Query: 747 DVDECA---AIPGLCA--PGRFRCVCGPGYRPAGEV-CADVDECAVRPPPCDQLCHNTDG 800
DVDEC+ C PG F C C GY G C D +EC++ C Q+C NT G
Sbjct: 364 DVDECSLDRTCDHSCINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVG 423
Query: 801 SYDCLCRTGYELDEDGANCRDV 822
SY+C C GY+L + +C +V
Sbjct: 424 SYECQCHPGYKLHWNKKDCVEV 445
Score = 52.8 bits (121), Expect = 5e-06
Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 15/123 (12%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGE--VCADVDE----CAVRPPPCDQL 794
DVDEC G C G + C C G+ + C E C + C +
Sbjct: 128 DVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHI 187
Query: 795 CHNTD-GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C GS C CR G+EL ++ +C + C CQ C +T ECSC Y+
Sbjct: 188 CKEAPRGSVACECRPGFELAKNQRDC--ILTCNHGNGGCQHSCDDTADGPECSCHPQYKM 245
Query: 854 RGD 856
D
Sbjct: 246 HTD 248
Score = 44.0 bits (99), Expect = 0.002
Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 2/40 (5%)
Query: 821 DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
DVDEC + C +C NT SY+CSC+ GY+ G C
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQC 84
Score = 35.1 bits (77), Expect = 1.1
Identities = 18/74 (24%), Positives = 29/74 (39%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
C+ I G C C PG+ A + C C C +T +C C Y
Sbjct: 184 CSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGGCQHSCDDTADGPECSCHPQY 243
Query: 811 ELDEDGANCRDVDE 824
++ DG +C + ++
Sbjct: 244 KMHTDGRSCLERED 257
>U69263-1|AAC51260.2| 956|Homo sapiens matrilin-2 precursor
protein.
Length = 956
Score = 194 bits (474), Expect = 8e-49
Identities = 122/399 (30%), Positives = 169/399 (42%), Gaps = 43/399 (10%)
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
C N GS+ C C GY L +D CR D C H C + C N G + C C +G
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ----LCVNVPGSFVCQCYSG 308
Query: 308 WKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
+ L G+RCV D C + C EC N +G Y+C+C G+ + C + + C
Sbjct: 309 YALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTCT--KIDYC 365
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
G H + C C +G PD RI + +P
Sbjct: 366 ASS-NHGCQHECVNTDDSY-SCHCLKGFTLN--------PDKKTCRRINYCALNKPGCEH 415
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
+ CVN + S+ C C GY L P+G +C D CA C C
Sbjct: 416 E---------------CVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCL 459
Query: 486 NTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
NT + CQCS GF D +TC VD C C + C N SF C CP G+ + +D
Sbjct: 460 NTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSD 519
Query: 545 GVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED 604
G C +D C C H+C + S++C+C EGY ++ C + C+ +
Sbjct: 520 GKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGY----ILREDGKTCRRKDVCQAIDH 575
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
C +C+N+D S+ C+C GF +EDG C RR C
Sbjct: 576 GCE-HICVNSDDSYTCECLVGFRLAEDGKRC--RRKDVC 611
Score = 193 bits (470), Expect = 3e-48
Identities = 124/396 (31%), Positives = 167/396 (42%), Gaps = 33/396 (8%)
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNE-CREGGMVCRNGRCRNTVGSFRCECAPGYTL 265
C N+PG+Y+C C G+ + + + C C C N GSF C+C GY L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKE 323
DG+ C VD C H C + C N +G Y C C G+ L + C D C
Sbjct: 312 AEDGKRCVAVDYCASENHGCEHE----CVNADGSYLCQCHEGFALNPDKKTCTKIDYCAS 367
Query: 324 LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-----------ERKELCYDEWEAG 372
+ C EC N + Y C C G+ + C E + + +E
Sbjct: 368 SNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYC 426
Query: 373 RCHRARPLQLARPECCCSEGAAWGRY-CERCPAPDSAEFMRICQGGMGRPNLTQDLDECR 431
RCHR L C + A + CE+ F+ C G + +DL C
Sbjct: 427 RCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGF---LINEDLKTCS 483
Query: 432 VRPDVCVGG------RCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
R D C+ CVN D SF C+CP+G+VL DG +C D CAL C + +C
Sbjct: 484 -RVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH-SCV 541
Query: 486 NTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
++ + CQC G+ D +TC D C C C N+ S+ C C G+ +A D
Sbjct: 542 SSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLVGFRLAED 601
Query: 545 GVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGY 580
G CR D C C H C N SYICKC EG+
Sbjct: 602 GKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGF 637
Score = 180 bits (437), Expect = 3e-44
Identities = 132/448 (29%), Positives = 182/448 (40%), Gaps = 50/448 (11%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
C + P + C C GY ++ CR D C+ C + CVN+PG+F C+C GY
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQL--CVNVPGSFVCQCYSGYA 310
Query: 143 LTPSLDECEDVDECGDQRI-CDHGDCRNTIGSYRCECKPGYTLR--ENVCRDVDECSRPR 199
L C VD C + C+H +C N GSY C+C G+ L + C +D C+
Sbjct: 311 LAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSN 369
Query: 200 PVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCRNGRCRNTVGSFRCE 258
C++ C N +Y CHC GF P+ C +N C C + C N S+ C
Sbjct: 370 HGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCR 427
Query: 259 CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCV 316
C GYTL +G+ C VD C + H C C NT + C C G+ + + C
Sbjct: 428 CHRGYTLDPNGKTCSRVDHCAQQDHGC----EQLCLNTEDSFVCQCSEGFLINEDLKTCS 483
Query: 317 DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHR 376
D C + C C N + + C+CP G C D C
Sbjct: 484 RVDYCLLSDHGCE-YSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVS 542
Query: 377 ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDE-CRVRPD 435
+ + C C EG Y R E + C+ R ++ Q +D C
Sbjct: 543 SEDSFV----CQCFEG-----YILR-------EDGKTCR----RKDVCQAIDHGCE---H 579
Query: 436 VCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQC 495
+C VN+D S+ CEC G+ LA DG C D C C + C N Y C+C
Sbjct: 580 IC-----VNSDDSYTCECLVGFRLAEDGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKC 633
Query: 496 SPGFTQGPD-QTCVDVDECAEGRASCTF 522
S GF D + C +C EG F
Sbjct: 634 SEGFVLAEDGRRC---KKCTEGPIDLVF 658
Score = 172 bits (418), Expect = 5e-42
Identities = 120/416 (28%), Positives = 169/416 (40%), Gaps = 37/416 (8%)
Query: 162 CDHGDCRNTIGSYRCECKPGYTLR--ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCD 219
C H C N GSY C CK GY L + CR D C+ C C N+PG+++C C
Sbjct: 249 CAHF-CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCY 306
Query: 220 DGFK-AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC 278
G+ A CV V+ C C + C N GS+ C+C G+ L D + C +D C
Sbjct: 307 SGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTCTKIDYC 365
Query: 279 DELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGG-----EC 333
H C + C NT+ Y C C G+ L D+ C+ + Y EC
Sbjct: 366 ASSNHGCQHE----CVNTDDSYSCHCLKGFTLNP----DKKTCRRINYCALNKPGCEHEC 417
Query: 334 RNFNGGYVCECPAGWRFDKTAAVC--VDER-------KELCYDEWEAGRCHRARPLQLAR 384
N Y C C G+ D C VD ++LC + ++ C + +
Sbjct: 418 VNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINE 477
Query: 385 PECCCSEG---AAWGRYCE-RCPAPDSAEFMRICQGGMGRPN--LTQDLDECRVRPDVCV 438
CS CE C D + + +G + R + LD C + C
Sbjct: 478 DLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCE 537
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPG 498
CV+++ SF C+C +GY+L DG +C D C C + C N+ Y C+C G
Sbjct: 538 HS-CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLVG 595
Query: 499 FTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDE 553
F D + C D C C C N S+ C C G+ +A DG C+ E
Sbjct: 596 FRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 651
Score = 118 bits (284), Expect = 9e-26
Identities = 66/173 (38%), Positives = 80/173 (46%), Gaps = 10/173 (5%)
Query: 484 CSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVA 542
C N G Y C+C G+ DQT C D CA +C C N GSF C C GYA+A
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312
Query: 543 ADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQ 602
DG C +D C E C H C N GSY+C+C EG+ A + C I+ C
Sbjct: 313 EDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGF----ALNPDKKTCTKIDYCASS 368
Query: 603 EDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPE 655
C C+NTD S+ C C GF + D C RR C +L CE E
Sbjct: 369 NHGCQ-HECVNTDDSYSCHCLKGFTLNPDKKTC--RRINYC--ALNKPGCEHE 416
Score = 109 bits (261), Expect = 5e-23
Identities = 69/228 (30%), Positives = 98/228 (42%), Gaps = 12/228 (5%)
Query: 55 GEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS 114
G ++P +D C C+ C +T F C C G+ + C VD C
Sbjct: 431 GYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCL 489
Query: 115 WGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIG 172
C CVN+ +F C+CP G+ L C +D C GD C+H C ++
Sbjct: 490 LSDHGCE--YSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHG-CEHS-CVSSED 545
Query: 173 SYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK-AGPNND 229
S+ C+C GY LRE+ CR D C C + C N +Y C C GF+ A
Sbjct: 546 SFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLVGFRLAEDGKR 604
Query: 230 CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE 277
C + C+ C + C N S+ C+C+ G+ L DGR C+ E
Sbjct: 605 CRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 651
Score = 89.8 bits (213), Expect = 4e-17
Identities = 40/99 (40%), Positives = 51/99 (51%), Gaps = 2/99 (2%)
Query: 760 PGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG + C C GY + C D CA+ C+QLC N GS+ C C +GY L EDG
Sbjct: 257 PGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGK 316
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C VD C + H C+ C N +GSY C C +G+ D
Sbjct: 317 RCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPD 355
Score = 89.0 bits (211), Expect = 6e-17
Identities = 41/99 (41%), Positives = 48/99 (48%), Gaps = 2/99 (2%)
Query: 760 PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG F C C GY A G+ C VD CA C+ C N DGSY C C G+ L+ D
Sbjct: 298 PGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKK 357
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C +D C H CQ C NT+ SY C C G+ D
Sbjct: 358 TCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPD 396
Score = 89.0 bits (211), Expect = 6e-17
Identities = 35/91 (38%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Query: 763 FRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
+ C C G+ P + C ++ CA+ P C+ C N + SY C C GY LD +G C
Sbjct: 383 YSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCS 442
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
VD C + H C+Q+C NTE S+ C C +G+
Sbjct: 443 RVDHCAQQDHGCEQLCLNTEDSFVCQCSEGF 473
Score = 85.4 bits (202), Expect = 8e-16
Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 2/96 (2%)
Query: 763 FRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
+ C C GY P G+ C+ VD CA + C+QLC NT+ S+ C C G+ ++ED C
Sbjct: 424 YYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCS 483
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
VD C H C+ C N + S+ C C +G+ R D
Sbjct: 484 RVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSD 519
Score = 85.4 bits (202), Expect = 8e-16
Identities = 37/91 (40%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Query: 763 FRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
F C C GY R G+ C D C C+ +C N+D SY C C G+ L EDG CR
Sbjct: 547 FVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLVGFRLAEDGKRCR 606
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
D C+ H C+ IC N SY C C +G+
Sbjct: 607 RKDVCKSTHHGCEHICVNNGNSYICKCSEGF 637
Score = 83.8 bits (198), Expect = 2e-15
Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 2/96 (2%)
Query: 763 FRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
F C C G+ R G+ CA +D CA+ C+ C +++ S+ C C GY L EDG CR
Sbjct: 506 FACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCR 565
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
D C+ H C+ IC N++ SY C C G+ D
Sbjct: 566 RKDVCQAIDHGCEHICVNSDDSYTCECLVGFRLAED 601
Score = 78.6 bits (185), Expect = 9e-14
Identities = 37/104 (35%), Positives = 48/104 (46%), Gaps = 4/104 (3%)
Query: 759 APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 816
A G + C C G+ P + C +D CA C C NTD SY C C G+ L+ D
Sbjct: 338 ADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDK 397
Query: 817 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDAC 858
CR ++ C + C+ C N E SY C C GY + G C
Sbjct: 398 KTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTC 441
Score = 73.3 bits (172), Expect = 3e-12
Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Query: 763 FRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
F C C G+ ++ C+ VD C + C+ C N D S+ C C G+ L DG C
Sbjct: 465 FVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCA 524
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
+D C H C+ C ++E S+ C C +GY R D
Sbjct: 525 KLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRED 560
Score = 72.5 bits (170), Expect = 6e-12
Identities = 31/78 (39%), Positives = 39/78 (50%), Gaps = 2/78 (2%)
Query: 784 CAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSY 843
C+ C C N GSY C C+ GY L+ D CR D C + H C+Q+C N GS+
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSF 301
Query: 844 ECSCEDGY--EKRGDACV 859
C C GY + G CV
Sbjct: 302 VCQCYSGYALAEDGKRCV 319
Score = 48.0 bits (109), Expect = 1e-04
Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Query: 763 FRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
+ C C G+R A G+ C D C C+ +C N SY C C G+ L EDG C+
Sbjct: 588 YTCECLVGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCK 647
Query: 821 DVDE 824
E
Sbjct: 648 KCTE 651
>BC016394-1|AAH16394.1| 715|Homo sapiens MATN2 protein protein.
Length = 715
Score = 194 bits (473), Expect = 1e-48
Identities = 122/399 (30%), Positives = 169/399 (42%), Gaps = 43/399 (10%)
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
C N GS+ C C GY L +D CR D C H C + C N G + C C +G
Sbjct: 12 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ----LCVNVPGSFVCQCYSG 67
Query: 308 WKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
+ L G+RCV D C + C EC N +G Y+C+C G+ + C + + C
Sbjct: 68 YALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTCT--KIDYC 124
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
G H + C C +G PD RI + +P
Sbjct: 125 ASS-NHGCQHECVNTDDSY-SCHCLKGFTLN--------PDKKTCRRINYCALNKPGCEH 174
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
+ CVN + S+ C C GY L P+G +C D CA C C
Sbjct: 175 E---------------CVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCL 218
Query: 486 NTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
NT + CQCS GF D +TC VD C C + C N SF C CP G+ + +D
Sbjct: 219 NTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSD 278
Query: 545 GVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED 604
G C +D C C H+C + S++C+C EGY ++ C + C+ +
Sbjct: 279 GKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGY----ILREDGKTCRRKDVCQAIDH 334
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
C +C+N+D S+ C+C GF +EDG C RR C
Sbjct: 335 GCE-HICVNSDDSYTCECLEGFRLAEDGKRC--RRKDVC 370
Score = 192 bits (469), Expect = 3e-48
Identities = 124/396 (31%), Positives = 167/396 (42%), Gaps = 33/396 (8%)
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNE-CREGGMVCRNGRCRNTVGSFRCECAPGYTL 265
C N+PG+Y+C C G+ + + + C C C N GSF C+C GY L
Sbjct: 12 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 70
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKE 323
DG+ C VD C H C + C N +G Y C C G+ L + C D C
Sbjct: 71 AEDGKRCVAVDYCASENHGCEHE----CVNADGSYLCQCHEGFALNPDEKTCTKIDYCAS 126
Query: 324 LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-----------ERKELCYDEWEAG 372
+ C EC N + Y C C G+ + C E + + +E
Sbjct: 127 SNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYC 185
Query: 373 RCHRARPLQLARPECCCSEGAAWGRY-CERCPAPDSAEFMRICQGGMGRPNLTQDLDECR 431
RCHR L C + A + CE+ F+ C G + +DL C
Sbjct: 186 RCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGF---LINEDLKTCS 242
Query: 432 VRPDVCVGG------RCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
R D C+ CVN D SF C+CP+G+VL DG +C D CAL C + +C
Sbjct: 243 -RVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH-SCV 300
Query: 486 NTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
++ + CQC G+ D +TC D C C C N+ S+ C C G+ +A D
Sbjct: 301 SSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAED 360
Query: 545 GVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGY 580
G CR D C C H C N SYICKC EG+
Sbjct: 361 GKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGF 396
Score = 183 bits (446), Expect = 2e-45
Identities = 133/448 (29%), Positives = 183/448 (40%), Gaps = 50/448 (11%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
C + P + C C GY ++ CR D C+ C + CVN+PG+F C+C GY
Sbjct: 12 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQL--CVNVPGSFVCQCYSGYA 69
Query: 143 LTPSLDECEDVDECGDQRI-CDHGDCRNTIGSYRCECKPGYTLR--ENVCRDVDECSRPR 199
L C VD C + C+H +C N GSY C+C G+ L E C +D C+
Sbjct: 70 LAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSN 128
Query: 200 PVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCRNGRCRNTVGSFRCE 258
C++ C N +Y CHC GF P+ C +N C C + C N S+ C
Sbjct: 129 HGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCR 186
Query: 259 CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCV 316
C GYTL +G+ C VD C + H C C NT + C C G+ + + C
Sbjct: 187 CHRGYTLDPNGKTCSRVDHCAQQDHGC----EQLCLNTEDSFVCQCSEGFLINEDLKTCS 242
Query: 317 DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHR 376
D C + C C N + + C+CP G C D C
Sbjct: 243 RVDYCLLSDHGCE-YSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVS 301
Query: 377 ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDE-CRVRPD 435
+ + C C EG Y R E + C+ R ++ Q +D C
Sbjct: 302 SEDSFV----CQCFEG-----YILR-------EDGKTCR----RKDVCQAIDHGCE---H 338
Query: 436 VCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQC 495
+C VN+D S+ CEC +G+ LA DG C D C C + C N Y C+C
Sbjct: 339 IC-----VNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKC 392
Query: 496 SPGFTQGPD-QTCVDVDECAEGRASCTF 522
S GF D + C +C EG F
Sbjct: 393 SEGFVLAEDGRRC---KKCTEGPIDLVF 417
Score = 172 bits (419), Expect = 4e-42
Identities = 120/416 (28%), Positives = 169/416 (40%), Gaps = 37/416 (8%)
Query: 162 CDHGDCRNTIGSYRCECKPGYTLR--ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCD 219
C H C N GSY C CK GY L + CR D C+ C C N+PG+++C C
Sbjct: 8 CAHF-CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCY 65
Query: 220 DGFK-AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC 278
G+ A CV V+ C C + C N GS+ C+C G+ L D + C +D C
Sbjct: 66 SGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTCTKIDYC 124
Query: 279 DELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGG-----EC 333
H C + C NT+ Y C C G+ L D+ C+ + Y EC
Sbjct: 125 ASSNHGCQHE----CVNTDDSYSCHCLKGFTLNP----DKKTCRRINYCALNKPGCEHEC 176
Query: 334 RNFNGGYVCECPAGWRFDKTAAVC--VDER-------KELCYDEWEAGRCHRARPLQLAR 384
N Y C C G+ D C VD ++LC + ++ C + +
Sbjct: 177 VNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINE 236
Query: 385 PECCCSEG---AAWGRYCE-RCPAPDSAEFMRICQGGMGRPN--LTQDLDECRVRPDVCV 438
CS CE C D + + +G + R + LD C + C
Sbjct: 237 DLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCE 296
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPG 498
CV+++ SF C+C +GY+L DG +C D C C + C N+ Y C+C G
Sbjct: 297 HS-CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEG 354
Query: 499 FTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDE 553
F D + C D C C C N S+ C C G+ +A DG C+ E
Sbjct: 355 FRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 410
Score = 120 bits (288), Expect = 3e-26
Identities = 67/173 (38%), Positives = 80/173 (46%), Gaps = 10/173 (5%)
Query: 484 CSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVA 542
C N G Y C+C G+ DQT C D CA +C C N GSF C C GYA+A
Sbjct: 12 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 71
Query: 543 ADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQ 602
DG C +D C E C H C N GSY+C+C EG+ A E C I+ C
Sbjct: 72 EDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGF----ALNPDEKTCTKIDYCASS 127
Query: 603 EDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPE 655
C C+NTD S+ C C GF + D C RR C +L CE E
Sbjct: 128 NHGCQ-HECVNTDDSYSCHCLKGFTLNPDKKTC--RRINYC--ALNKPGCEHE 175
Score = 111 bits (266), Expect = 1e-23
Identities = 69/228 (30%), Positives = 99/228 (43%), Gaps = 12/228 (5%)
Query: 55 GEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS 114
G ++P +D C C+ C +T F C C G+ + C VD C
Sbjct: 190 GYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCL 248
Query: 115 WGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIG 172
C CVN+ +F C+CP G+ L C +D C GD C+H C ++
Sbjct: 249 LSDHGCE--YSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHG-CEHS-CVSSED 304
Query: 173 SYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK-AGPNND 229
S+ C+C GY LRE+ CR D C C + C N +Y C C +GF+ A
Sbjct: 305 SFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKR 363
Query: 230 CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE 277
C + C+ C + C N S+ C+C+ G+ L DGR C+ E
Sbjct: 364 CRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 410
Score = 89.8 bits (213), Expect = 4e-17
Identities = 40/99 (40%), Positives = 51/99 (51%), Gaps = 2/99 (2%)
Query: 760 PGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG + C C GY + C D CA+ C+QLC N GS+ C C +GY L EDG
Sbjct: 16 PGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGK 75
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C VD C + H C+ C N +GSY C C +G+ D
Sbjct: 76 RCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPD 114
Score = 89.0 bits (211), Expect = 6e-17
Identities = 41/99 (41%), Positives = 48/99 (48%), Gaps = 2/99 (2%)
Query: 760 PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG F C C GY A G+ C VD CA C+ C N DGSY C C G+ L+ D
Sbjct: 57 PGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEK 116
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C +D C H CQ C NT+ SY C C G+ D
Sbjct: 117 TCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPD 155
Score = 89.0 bits (211), Expect = 6e-17
Identities = 35/91 (38%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Query: 763 FRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
+ C C G+ P + C ++ CA+ P C+ C N + SY C C GY LD +G C
Sbjct: 142 YSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCS 201
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
VD C + H C+Q+C NTE S+ C C +G+
Sbjct: 202 RVDHCAQQDHGCEQLCLNTEDSFVCQCSEGF 232
Score = 85.8 bits (203), Expect = 6e-16
Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 2/96 (2%)
Query: 763 FRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
F C C G+ R G+ CA +D CA+ C+ C +++ S+ C C GY L EDG CR
Sbjct: 265 FACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCR 324
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
D C+ H C+ IC N++ SY C C +G+ D
Sbjct: 325 RKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAED 360
Score = 85.4 bits (202), Expect = 8e-16
Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 2/96 (2%)
Query: 763 FRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
+ C C GY P G+ C+ VD CA + C+QLC NT+ S+ C C G+ ++ED C
Sbjct: 183 YYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCS 242
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
VD C H C+ C N + S+ C C +G+ R D
Sbjct: 243 RVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSD 278
Score = 85.0 bits (201), Expect = 1e-15
Identities = 37/91 (40%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Query: 763 FRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
F C C GY R G+ C D C C+ +C N+D SY C C G+ L EDG CR
Sbjct: 306 FVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCR 365
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
D C+ H C+ IC N SY C C +G+
Sbjct: 366 RKDVCKSTHHGCEHICVNNGNSYICKCSEGF 396
Score = 78.6 bits (185), Expect = 9e-14
Identities = 37/104 (35%), Positives = 48/104 (46%), Gaps = 4/104 (3%)
Query: 759 APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 816
A G + C C G+ P + C +D CA C C NTD SY C C G+ L+ D
Sbjct: 97 ADGSYLCQCHEGFALNPDEKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDK 156
Query: 817 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDAC 858
CR ++ C + C+ C N E SY C C GY + G C
Sbjct: 157 KTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTC 200
Score = 73.3 bits (172), Expect = 3e-12
Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Query: 763 FRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
F C C G+ ++ C+ VD C + C+ C N D S+ C C G+ L DG C
Sbjct: 224 FVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCA 283
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
+D C H C+ C ++E S+ C C +GY R D
Sbjct: 284 KLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRED 319
Score = 72.5 bits (170), Expect = 6e-12
Identities = 31/78 (39%), Positives = 39/78 (50%), Gaps = 2/78 (2%)
Query: 784 CAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSY 843
C+ C C N GSY C C+ GY L+ D CR D C + H C+Q+C N GS+
Sbjct: 1 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSF 60
Query: 844 ECSCEDGY--EKRGDACV 859
C C GY + G CV
Sbjct: 61 VCQCYSGYALAEDGKRCV 78
Score = 48.4 bits (110), Expect = 1e-04
Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Query: 763 FRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
+ C C G+R A G+ C D C C+ +C N SY C C G+ L EDG C+
Sbjct: 347 YTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCK 406
Query: 821 DVDE 824
E
Sbjct: 407 KCTE 410
>BC010444-1|AAH10444.1| 937|Homo sapiens matrilin 2 protein.
Length = 937
Score = 194 bits (473), Expect = 1e-48
Identities = 122/399 (30%), Positives = 169/399 (42%), Gaps = 43/399 (10%)
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
C N GS+ C C GY L +D CR D C H C + C N G + C C +G
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ----LCVNVPGSFVCQCYSG 308
Query: 308 WKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
+ L G+RCV D C + C EC N +G Y+C+C G+ + C + + C
Sbjct: 309 YALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTCT--KIDYC 365
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
G H + C C +G PD RI + +P
Sbjct: 366 ASS-NHGCQHECVNTDDSY-SCHCLKGFTLN--------PDKKTCRRINYCALNKPGCEH 415
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
+ CVN + S+ C C GY L P+G +C D CA C C
Sbjct: 416 E---------------CVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCL 459
Query: 486 NTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
NT + CQCS GF D +TC VD C C + C N SF C CP G+ + +D
Sbjct: 460 NTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSD 519
Query: 545 GVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED 604
G C +D C C H+C + S++C+C EGY ++ C + C+ +
Sbjct: 520 GKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGY----ILREDGKTCRRKDVCQAIDH 575
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
C +C+N+D S+ C+C GF +EDG C RR C
Sbjct: 576 GCE-HICVNSDDSYTCECLEGFRLAEDGKRC--RRKDVC 611
Score = 192 bits (469), Expect = 3e-48
Identities = 124/396 (31%), Positives = 167/396 (42%), Gaps = 33/396 (8%)
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNE-CREGGMVCRNGRCRNTVGSFRCECAPGYTL 265
C N+PG+Y+C C G+ + + + C C C N GSF C+C GY L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKE 323
DG+ C VD C H C + C N +G Y C C G+ L + C D C
Sbjct: 312 AEDGKRCVAVDYCASENHGCEHE----CVNADGSYLCQCHEGFALNPDEKTCTKIDYCAS 367
Query: 324 LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-----------ERKELCYDEWEAG 372
+ C EC N + Y C C G+ + C E + + +E
Sbjct: 368 SNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYC 426
Query: 373 RCHRARPLQLARPECCCSEGAAWGRY-CERCPAPDSAEFMRICQGGMGRPNLTQDLDECR 431
RCHR L C + A + CE+ F+ C G + +DL C
Sbjct: 427 RCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGF---LINEDLKTCS 483
Query: 432 VRPDVCVGG------RCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
R D C+ CVN D SF C+CP+G+VL DG +C D CAL C + +C
Sbjct: 484 -RVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH-SCV 541
Query: 486 NTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
++ + CQC G+ D +TC D C C C N+ S+ C C G+ +A D
Sbjct: 542 SSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAED 601
Query: 545 GVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGY 580
G CR D C C H C N SYICKC EG+
Sbjct: 602 GKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGF 637
Score = 183 bits (446), Expect = 2e-45
Identities = 133/448 (29%), Positives = 183/448 (40%), Gaps = 50/448 (11%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
C + P + C C GY ++ CR D C+ C + CVN+PG+F C+C GY
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQL--CVNVPGSFVCQCYSGYA 310
Query: 143 LTPSLDECEDVDECGDQRI-CDHGDCRNTIGSYRCECKPGYTLR--ENVCRDVDECSRPR 199
L C VD C + C+H +C N GSY C+C G+ L E C +D C+
Sbjct: 311 LAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSN 369
Query: 200 PVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCRNGRCRNTVGSFRCE 258
C++ C N +Y CHC GF P+ C +N C C + C N S+ C
Sbjct: 370 HGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCR 427
Query: 259 CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCV 316
C GYTL +G+ C VD C + H C C NT + C C G+ + + C
Sbjct: 428 CHRGYTLDPNGKTCSRVDHCAQQDHGC----EQLCLNTEDSFVCQCSEGFLINEDLKTCS 483
Query: 317 DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHR 376
D C + C C N + + C+CP G C D C
Sbjct: 484 RVDYCLLSDHGCE-YSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVS 542
Query: 377 ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDE-CRVRPD 435
+ + C C EG Y R E + C+ R ++ Q +D C
Sbjct: 543 SEDSFV----CQCFEG-----YILR-------EDGKTCR----RKDVCQAIDHGCE---H 579
Query: 436 VCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQC 495
+C VN+D S+ CEC +G+ LA DG C D C C + C N Y C+C
Sbjct: 580 IC-----VNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKC 633
Query: 496 SPGFTQGPD-QTCVDVDECAEGRASCTF 522
S GF D + C +C EG F
Sbjct: 634 SEGFVLAEDGRRC---KKCTEGPIDLVF 658
Score = 172 bits (419), Expect = 4e-42
Identities = 120/416 (28%), Positives = 169/416 (40%), Gaps = 37/416 (8%)
Query: 162 CDHGDCRNTIGSYRCECKPGYTLR--ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCD 219
C H C N GSY C CK GY L + CR D C+ C C N+PG+++C C
Sbjct: 249 CAHF-CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCY 306
Query: 220 DGFK-AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC 278
G+ A CV V+ C C + C N GS+ C+C G+ L D + C +D C
Sbjct: 307 SGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTCTKIDYC 365
Query: 279 DELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGG-----EC 333
H C + C NT+ Y C C G+ L D+ C+ + Y EC
Sbjct: 366 ASSNHGCQHE----CVNTDDSYSCHCLKGFTLNP----DKKTCRRINYCALNKPGCEHEC 417
Query: 334 RNFNGGYVCECPAGWRFDKTAAVC--VDER-------KELCYDEWEAGRCHRARPLQLAR 384
N Y C C G+ D C VD ++LC + ++ C + +
Sbjct: 418 VNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINE 477
Query: 385 PECCCSEG---AAWGRYCE-RCPAPDSAEFMRICQGGMGRPN--LTQDLDECRVRPDVCV 438
CS CE C D + + +G + R + LD C + C
Sbjct: 478 DLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCE 537
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPG 498
CV+++ SF C+C +GY+L DG +C D C C + C N+ Y C+C G
Sbjct: 538 HS-CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEG 595
Query: 499 FTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDE 553
F D + C D C C C N S+ C C G+ +A DG C+ E
Sbjct: 596 FRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 651
Score = 120 bits (288), Expect = 3e-26
Identities = 67/173 (38%), Positives = 80/173 (46%), Gaps = 10/173 (5%)
Query: 484 CSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVA 542
C N G Y C+C G+ DQT C D CA +C C N GSF C C GYA+A
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312
Query: 543 ADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQ 602
DG C +D C E C H C N GSY+C+C EG+ A E C I+ C
Sbjct: 313 EDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGF----ALNPDEKTCTKIDYCASS 368
Query: 603 EDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPE 655
C C+NTD S+ C C GF + D C RR C +L CE E
Sbjct: 369 NHGCQ-HECVNTDDSYSCHCLKGFTLNPDKKTC--RRINYC--ALNKPGCEHE 416
Score = 111 bits (266), Expect = 1e-23
Identities = 69/228 (30%), Positives = 99/228 (43%), Gaps = 12/228 (5%)
Query: 55 GEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS 114
G ++P +D C C+ C +T F C C G+ + C VD C
Sbjct: 431 GYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCL 489
Query: 115 WGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIG 172
C CVN+ +F C+CP G+ L C +D C GD C+H C ++
Sbjct: 490 LSDHGCE--YSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHG-CEHS-CVSSED 545
Query: 173 SYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK-AGPNND 229
S+ C+C GY LRE+ CR D C C + C N +Y C C +GF+ A
Sbjct: 546 SFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKR 604
Query: 230 CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE 277
C + C+ C + C N S+ C+C+ G+ L DGR C+ E
Sbjct: 605 CRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 651
Score = 89.8 bits (213), Expect = 4e-17
Identities = 40/99 (40%), Positives = 51/99 (51%), Gaps = 2/99 (2%)
Query: 760 PGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG + C C GY + C D CA+ C+QLC N GS+ C C +GY L EDG
Sbjct: 257 PGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGK 316
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C VD C + H C+ C N +GSY C C +G+ D
Sbjct: 317 RCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPD 355
Score = 89.0 bits (211), Expect = 6e-17
Identities = 41/99 (41%), Positives = 48/99 (48%), Gaps = 2/99 (2%)
Query: 760 PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG F C C GY A G+ C VD CA C+ C N DGSY C C G+ L+ D
Sbjct: 298 PGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEK 357
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C +D C H CQ C NT+ SY C C G+ D
Sbjct: 358 TCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPD 396
Score = 89.0 bits (211), Expect = 6e-17
Identities = 35/91 (38%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Query: 763 FRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
+ C C G+ P + C ++ CA+ P C+ C N + SY C C GY LD +G C
Sbjct: 383 YSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCS 442
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
VD C + H C+Q+C NTE S+ C C +G+
Sbjct: 443 RVDHCAQQDHGCEQLCLNTEDSFVCQCSEGF 473
Score = 85.8 bits (203), Expect = 6e-16
Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 2/96 (2%)
Query: 763 FRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
F C C G+ R G+ CA +D CA+ C+ C +++ S+ C C GY L EDG CR
Sbjct: 506 FACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCR 565
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
D C+ H C+ IC N++ SY C C +G+ D
Sbjct: 566 RKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAED 601
Score = 85.4 bits (202), Expect = 8e-16
Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 2/96 (2%)
Query: 763 FRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
+ C C GY P G+ C+ VD CA + C+QLC NT+ S+ C C G+ ++ED C
Sbjct: 424 YYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCS 483
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
VD C H C+ C N + S+ C C +G+ R D
Sbjct: 484 RVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSD 519
Score = 85.0 bits (201), Expect = 1e-15
Identities = 37/91 (40%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Query: 763 FRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
F C C GY R G+ C D C C+ +C N+D SY C C G+ L EDG CR
Sbjct: 547 FVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCR 606
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
D C+ H C+ IC N SY C C +G+
Sbjct: 607 RKDVCKSTHHGCEHICVNNGNSYICKCSEGF 637
Score = 78.6 bits (185), Expect = 9e-14
Identities = 37/104 (35%), Positives = 48/104 (46%), Gaps = 4/104 (3%)
Query: 759 APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 816
A G + C C G+ P + C +D CA C C NTD SY C C G+ L+ D
Sbjct: 338 ADGSYLCQCHEGFALNPDEKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDK 397
Query: 817 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDAC 858
CR ++ C + C+ C N E SY C C GY + G C
Sbjct: 398 KTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTC 441
Score = 73.3 bits (172), Expect = 3e-12
Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Query: 763 FRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
F C C G+ ++ C+ VD C + C+ C N D S+ C C G+ L DG C
Sbjct: 465 FVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCA 524
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
+D C H C+ C ++E S+ C C +GY R D
Sbjct: 525 KLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRED 560
Score = 72.5 bits (170), Expect = 6e-12
Identities = 31/78 (39%), Positives = 39/78 (50%), Gaps = 2/78 (2%)
Query: 784 CAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSY 843
C+ C C N GSY C C+ GY L+ D CR D C + H C+Q+C N GS+
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSF 301
Query: 844 ECSCEDGY--EKRGDACV 859
C C GY + G CV
Sbjct: 302 VCQCYSGYALAEDGKRCV 319
Score = 48.4 bits (110), Expect = 1e-04
Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Query: 763 FRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
+ C C G+R A G+ C D C C+ +C N SY C C G+ L EDG C+
Sbjct: 588 YTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCK 647
Query: 821 DVDE 824
E
Sbjct: 648 KCTE 651
>AL833931-1|CAD38787.1| 1016|Homo sapiens hypothetical protein
protein.
Length = 1016
Score = 194 bits (473), Expect = 1e-48
Identities = 122/399 (30%), Positives = 169/399 (42%), Gaps = 43/399 (10%)
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
C N GS+ C C GY L +D CR D C H C + C N G + C C +G
Sbjct: 313 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ----LCVNVPGSFVCQCYSG 368
Query: 308 WKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
+ L G+RCV D C + C EC N +G Y+C+C G+ + C + + C
Sbjct: 369 YALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTCT--KIDYC 425
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
G H + C C +G PD RI + +P
Sbjct: 426 ASS-NHGCQHECVNTDDSY-SCHCLKGFTLN--------PDKKTCRRINYCALNKPGCEH 475
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
+ CVN + S+ C C GY L P+G +C D CA C C
Sbjct: 476 E---------------CVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCL 519
Query: 486 NTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
NT + CQCS GF D +TC VD C C + C N SF C CP G+ + +D
Sbjct: 520 NTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSD 579
Query: 545 GVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED 604
G C +D C C H+C + S++C+C EGY ++ C + C+ +
Sbjct: 580 GKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGY----ILREDGKTCRRKDVCQAIDH 635
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
C +C+N+D S+ C+C GF +EDG C RR C
Sbjct: 636 GCE-HICVNSDDSYTCECLEGFRLAEDGKRC--RRKDVC 671
Score = 192 bits (469), Expect = 3e-48
Identities = 124/396 (31%), Positives = 167/396 (42%), Gaps = 33/396 (8%)
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNE-CREGGMVCRNGRCRNTVGSFRCECAPGYTL 265
C N+PG+Y+C C G+ + + + C C C N GSF C+C GY L
Sbjct: 313 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 371
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKE 323
DG+ C VD C H C + C N +G Y C C G+ L + C D C
Sbjct: 372 AEDGKRCVAVDYCASENHGCEHE----CVNADGSYLCQCHEGFALNPDEKTCTKIDYCAS 427
Query: 324 LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD-----------ERKELCYDEWEAG 372
+ C EC N + Y C C G+ + C E + + +E
Sbjct: 428 SNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYC 486
Query: 373 RCHRARPLQLARPECCCSEGAAWGRY-CERCPAPDSAEFMRICQGGMGRPNLTQDLDECR 431
RCHR L C + A + CE+ F+ C G + +DL C
Sbjct: 487 RCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGF---LINEDLKTCS 543
Query: 432 VRPDVCVGG------RCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
R D C+ CVN D SF C+CP+G+VL DG +C D CAL C + +C
Sbjct: 544 -RVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH-SCV 601
Query: 486 NTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
++ + CQC G+ D +TC D C C C N+ S+ C C G+ +A D
Sbjct: 602 SSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAED 661
Query: 545 GVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGY 580
G CR D C C H C N SYICKC EG+
Sbjct: 662 GKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGF 697
Score = 183 bits (446), Expect = 2e-45
Identities = 133/448 (29%), Positives = 183/448 (40%), Gaps = 50/448 (11%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
C + P + C C GY ++ CR D C+ C + CVN+PG+F C+C GY
Sbjct: 313 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQL--CVNVPGSFVCQCYSGYA 370
Query: 143 LTPSLDECEDVDECGDQRI-CDHGDCRNTIGSYRCECKPGYTLR--ENVCRDVDECSRPR 199
L C VD C + C+H +C N GSY C+C G+ L E C +D C+
Sbjct: 371 LAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSN 429
Query: 200 PVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCRNGRCRNTVGSFRCE 258
C++ C N +Y CHC GF P+ C +N C C + C N S+ C
Sbjct: 430 HGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCR 487
Query: 259 CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCV 316
C GYTL +G+ C VD C + H C C NT + C C G+ + + C
Sbjct: 488 CHRGYTLDPNGKTCSRVDHCAQQDHGC----EQLCLNTEDSFVCQCSEGFLINEDLKTCS 543
Query: 317 DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHR 376
D C + C C N + + C+CP G C D C
Sbjct: 544 RVDYCLLSDHGCE-YSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVS 602
Query: 377 ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDE-CRVRPD 435
+ + C C EG Y R E + C+ R ++ Q +D C
Sbjct: 603 SEDSFV----CQCFEG-----YILR-------EDGKTCR----RKDVCQAIDHGCE---H 639
Query: 436 VCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQC 495
+C VN+D S+ CEC +G+ LA DG C D C C + C N Y C+C
Sbjct: 640 IC-----VNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKC 693
Query: 496 SPGFTQGPD-QTCVDVDECAEGRASCTF 522
S GF D + C +C EG F
Sbjct: 694 SEGFVLAEDGRRC---KKCTEGPIDLVF 718
Score = 172 bits (419), Expect = 4e-42
Identities = 120/416 (28%), Positives = 169/416 (40%), Gaps = 37/416 (8%)
Query: 162 CDHGDCRNTIGSYRCECKPGYTLR--ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCD 219
C H C N GSY C CK GY L + CR D C+ C C N+PG+++C C
Sbjct: 309 CAHF-CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCY 366
Query: 220 DGFK-AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC 278
G+ A CV V+ C C + C N GS+ C+C G+ L D + C +D C
Sbjct: 367 SGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTCTKIDYC 425
Query: 279 DELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGG-----EC 333
H C + C NT+ Y C C G+ L D+ C+ + Y EC
Sbjct: 426 ASSNHGCQHE----CVNTDDSYSCHCLKGFTLNP----DKKTCRRINYCALNKPGCEHEC 477
Query: 334 RNFNGGYVCECPAGWRFDKTAAVC--VDER-------KELCYDEWEAGRCHRARPLQLAR 384
N Y C C G+ D C VD ++LC + ++ C + +
Sbjct: 478 VNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINE 537
Query: 385 PECCCSEG---AAWGRYCE-RCPAPDSAEFMRICQGGMGRPN--LTQDLDECRVRPDVCV 438
CS CE C D + + +G + R + LD C + C
Sbjct: 538 DLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCE 597
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPG 498
CV+++ SF C+C +GY+L DG +C D C C + C N+ Y C+C G
Sbjct: 598 HS-CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEG 655
Query: 499 FTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDE 553
F D + C D C C C N S+ C C G+ +A DG C+ E
Sbjct: 656 FRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 711
Score = 120 bits (288), Expect = 3e-26
Identities = 67/173 (38%), Positives = 80/173 (46%), Gaps = 10/173 (5%)
Query: 484 CSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVA 542
C N G Y C+C G+ DQT C D CA +C C N GSF C C GYA+A
Sbjct: 313 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 372
Query: 543 ADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQ 602
DG C +D C E C H C N GSY+C+C EG+ A E C I+ C
Sbjct: 373 EDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGF----ALNPDEKTCTKIDYCASS 428
Query: 603 EDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPE 655
C C+NTD S+ C C GF + D C RR C +L CE E
Sbjct: 429 NHGCQ-HECVNTDDSYSCHCLKGFTLNPDKKTC--RRINYC--ALNKPGCEHE 476
Score = 111 bits (266), Expect = 1e-23
Identities = 69/228 (30%), Positives = 99/228 (43%), Gaps = 12/228 (5%)
Query: 55 GEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS 114
G ++P +D C C+ C +T F C C G+ + C VD C
Sbjct: 491 GYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCL 549
Query: 115 WGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIG 172
C CVN+ +F C+CP G+ L C +D C GD C+H C ++
Sbjct: 550 LSDHGCE--YSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHG-CEHS-CVSSED 605
Query: 173 SYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK-AGPNND 229
S+ C+C GY LRE+ CR D C C + C N +Y C C +GF+ A
Sbjct: 606 SFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKR 664
Query: 230 CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE 277
C + C+ C + C N S+ C+C+ G+ L DGR C+ E
Sbjct: 665 CRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 711
Score = 89.8 bits (213), Expect = 4e-17
Identities = 40/99 (40%), Positives = 51/99 (51%), Gaps = 2/99 (2%)
Query: 760 PGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG + C C GY + C D CA+ C+QLC N GS+ C C +GY L EDG
Sbjct: 317 PGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGK 376
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C VD C + H C+ C N +GSY C C +G+ D
Sbjct: 377 RCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPD 415
Score = 89.0 bits (211), Expect = 6e-17
Identities = 41/99 (41%), Positives = 48/99 (48%), Gaps = 2/99 (2%)
Query: 760 PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG F C C GY A G+ C VD CA C+ C N DGSY C C G+ L+ D
Sbjct: 358 PGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEK 417
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C +D C H CQ C NT+ SY C C G+ D
Sbjct: 418 TCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPD 456
Score = 89.0 bits (211), Expect = 6e-17
Identities = 35/91 (38%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Query: 763 FRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
+ C C G+ P + C ++ CA+ P C+ C N + SY C C GY LD +G C
Sbjct: 443 YSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCS 502
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
VD C + H C+Q+C NTE S+ C C +G+
Sbjct: 503 RVDHCAQQDHGCEQLCLNTEDSFVCQCSEGF 533
Score = 85.8 bits (203), Expect = 6e-16
Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 2/96 (2%)
Query: 763 FRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
F C C G+ R G+ CA +D CA+ C+ C +++ S+ C C GY L EDG CR
Sbjct: 566 FACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCR 625
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
D C+ H C+ IC N++ SY C C +G+ D
Sbjct: 626 RKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAED 661
Score = 85.4 bits (202), Expect = 8e-16
Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 2/96 (2%)
Query: 763 FRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
+ C C GY P G+ C+ VD CA + C+QLC NT+ S+ C C G+ ++ED C
Sbjct: 484 YYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCS 543
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
VD C H C+ C N + S+ C C +G+ R D
Sbjct: 544 RVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSD 579
Score = 85.0 bits (201), Expect = 1e-15
Identities = 37/91 (40%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Query: 763 FRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
F C C GY R G+ C D C C+ +C N+D SY C C G+ L EDG CR
Sbjct: 607 FVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCR 666
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
D C+ H C+ IC N SY C C +G+
Sbjct: 667 RKDVCKSTHHGCEHICVNNGNSYICKCSEGF 697
Score = 78.6 bits (185), Expect = 9e-14
Identities = 37/104 (35%), Positives = 48/104 (46%), Gaps = 4/104 (3%)
Query: 759 APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 816
A G + C C G+ P + C +D CA C C NTD SY C C G+ L+ D
Sbjct: 398 ADGSYLCQCHEGFALNPDEKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDK 457
Query: 817 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDAC 858
CR ++ C + C+ C N E SY C C GY + G C
Sbjct: 458 KTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTC 501
Score = 73.3 bits (172), Expect = 3e-12
Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Query: 763 FRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
F C C G+ ++ C+ VD C + C+ C N D S+ C C G+ L DG C
Sbjct: 525 FVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCA 584
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
+D C H C+ C ++E S+ C C +GY R D
Sbjct: 585 KLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRED 620
Score = 72.5 bits (170), Expect = 6e-12
Identities = 31/78 (39%), Positives = 39/78 (50%), Gaps = 2/78 (2%)
Query: 784 CAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSY 843
C+ C C N GSY C C+ GY L+ D CR D C + H C+Q+C N GS+
Sbjct: 302 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSF 361
Query: 844 ECSCEDGY--EKRGDACV 859
C C GY + G CV
Sbjct: 362 VCQCYSGYALAEDGKRCV 379
Score = 48.4 bits (110), Expect = 1e-04
Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Query: 763 FRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
+ C C G+R A G+ C D C C+ +C N SY C C G+ L EDG C+
Sbjct: 648 YTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCK 707
Query: 821 DVDE 824
E
Sbjct: 708 KCTE 711
>U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.
Length = 2003
Score = 193 bits (470), Expect = 3e-48
Identities = 167/563 (29%), Positives = 242/563 (42%), Gaps = 80/563 (14%)
Query: 92 CGCDHGYEHDNTSHLCRDVDEC---SWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD 148
C C GY T H +D+DEC G PC C+N PG+F C CPPGY T S
Sbjct: 418 CLCQPGYSGP-TCH--QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGS-- 470
Query: 149 ECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGT 206
CE D +EC Q C + + ++ C C PG L +C + +EC+ P +
Sbjct: 471 RCEADHNECLSQPCHPGSTCLDLLATFHCLCPPG--LEGQLCEVETNECA-SAPCLNHAD 527
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTL 265
C +L + C C GF + D++ECR C N G+C++ G+F C+C PG+
Sbjct: 528 CHDLLNGFQCICLPGFSGTRCEE--DIDECRSS--PCANGGQCQDQPGAFHCKCLPGF-- 581
Query: 266 TADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKEL 324
+G C+ +VDEC P P G SC + G + C C +G+ G+ C + C
Sbjct: 582 --EGPRCQTEVDECLSDPCPVG----ASCLDLPGAFFCLCPSGF--TGQLC-EVPLC--A 630
Query: 325 PYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRAR---PL 380
P +C + C++ C CP D + E C+ G C R+ +
Sbjct: 631 PNLCQPKQICKDQKDKANCLCP-----DGSPGCAPPEDNCTCHH----GHCQRSSCVCDV 681
Query: 381 QLARPEC------CCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP 434
PEC C S A G C P + + C G P ++++ C P
Sbjct: 682 GWTGPECEAELGGCISAPCAHGGTC----YPQPSGYNCTCPTGYTGPTCSEEMTACHSGP 737
Query: 435 DVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYE 492
C+ GG C + G + C CP + G C D C P G GTC N G +
Sbjct: 738 --CLNGGSCNPSPGGYYCTCPPSHT----GPQCQTSTDYCVSAPCFNG-GTCVNRPGTFS 790
Query: 493 CQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI- 551
C C+ GF QGP CA+ C ++ RC CP GY G C+ +
Sbjct: 791 CLCAMGF-QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYT----GGSCQTLM 845
Query: 552 DECVQEPRVCPH--ACENVVGSYICKCPEGYR--RTSAPQDSENACEDINECEEQEDLC- 606
D C Q+P CP C S+ C C +G+ + P S +++ + LC
Sbjct: 846 DLCAQKP--CPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAA-LSQGIDVSSLCH 902
Query: 607 SGGVCINTDGSFLCDCDAGFEPS 629
+GG+C+++ S+ C C GF+ S
Sbjct: 903 NGGLCVDSGPSYFCHCPPGFQGS 925
Score = 186 bits (454), Expect = 2e-46
Identities = 191/641 (29%), Positives = 255/641 (39%), Gaps = 118/641 (18%)
Query: 33 APCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKP----GTCHDTPT 88
A C P GS LC +PG Y P ++ +DEC + Q P G+C +TP
Sbjct: 405 AQCSTNPLTGS----TLCLCQPG-YSGPTCHQD--LDECLMAQQGPSPCEHGGSCLNTPG 457
Query: 89 GFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
F C C GY T C D +EC PC + C++L F C CPPG L L
Sbjct: 458 SFNCLCPPGY----TGSRCEADHNECL--SQPCHPGSTCLDLLATFHCLCPPG--LEGQL 509
Query: 148 DECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTC 207
E E +EC +H DC + + ++C C PG++ D+DEC R P G C
Sbjct: 510 CEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS-GTRCEEDIDEC-RSSPCANGGQC 566
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYT-- 264
++ PGA+ C C GF+ GP +V+EC C G C + G+F C C G+T
Sbjct: 567 QDQPGAFHCKCLPGFE-GPRCQ-TEVDECLSD--PCPVGASCLDLPGAFFCLCPSGFTGQ 622
Query: 265 ----------LTADGRNCRDVDECDELPHPCGRDG----NPSCTNTNGGYE---CSCGAG 307
L + C+D + P G G +CT +G + C C G
Sbjct: 623 LCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVG 682
Query: 308 WKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
W G C + C P CA GG C GY C CP G+ T C E C
Sbjct: 683 W--TGPECEAELGGCISAP--CAHGGTCYPQPSGYNCTCPTGY----TGPTC-SEEMTAC 733
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
+ +G C L C S G G YC CP + P
Sbjct: 734 H----SGPC-------LNGGSCNPSPG---GYYC-TCPPSHTG------------PQCQT 766
Query: 426 DLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVD--ADECALDPRICGN- 481
D C P C GG CVN G+F C C G+ G C CA P C N
Sbjct: 767 STDYCVSAP--CFNGGTCVNRPGTFSCLCAMGF----QGPRCEGKLRPSCADSP--CRNR 818
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA- 540
TC ++ G C C G+T G QT +D+ CA+ C T SF C C G+
Sbjct: 819 ATCQDSPQGPRCLCPTGYTGGSCQTLMDL--CAQKPCPRNSHCLQTGPSFHCLCLQGWTG 876
Query: 541 ----VAADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENACE 594
+ + + + +C + C + SY C CP G+ + S QD N CE
Sbjct: 877 PLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF-QGSLCQDHVNPCE 935
Query: 595 DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
C+ +G C+ +LC C G+ DG +C
Sbjct: 936 S-RPCQ------NGATCMAQPSGYLCQCAPGY----DGQNC 965
Score = 178 bits (433), Expect = 8e-44
Identities = 182/654 (27%), Positives = 268/654 (40%), Gaps = 107/654 (16%)
Query: 21 YLCCCSVGHAWGAPCEA-----CPP----RGSPAHTALCGEKPGEYINPVTNETKPI-DE 70
+LC C G G C+A CPP + H G + T E + D
Sbjct: 101 FLCTCLPGFT-GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDF 159
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNL 129
C P + G C T QC C G+E H C RDV+EC PC C N
Sbjct: 160 CSANPCV-NGGVCLATYPQIQCHCPPGFE----GHACERDVNECFQDPGPCPKGTSCHNT 214
Query: 130 PGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCR----NTIGSYRCECKPGYTL 184
G+F+C CP G P CE C + + G C+ + C C PG+ +
Sbjct: 215 LGSFQCLCPVGQE-GP---RCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGF-I 269
Query: 185 RENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCV-DVNECR-EGGM 241
+ + D C + C+NG TC++ Y C C + + DC DV+EC +G
Sbjct: 270 GPDCEVNPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGW---DCSEDVDECETQGPP 324
Query: 242 VCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGG 299
CRNG C+N+ GSF C C G+ G +C + +D+C + C +C + G
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDC--IAATCA--PGSTCIDRVGS 376
Query: 300 YECSCGAGWKLVGRRCVDRDECKELPYVCAG-GECRN--FNGGYVCECPAGWRFDKTAAV 356
+ C C G G C D C P C G +C G +C C G+ +
Sbjct: 377 FSCLCPPG--RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTLCLCQPGY----SGPT 428
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
C + E C A+ Q P C G + C P F +C
Sbjct: 429 CHQDLDE----------CLMAQ--QGPSP---CEHGGS----CLNTP----GSFNCLCPP 465
Query: 417 GMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALD 475
G D +EC +P G C++ +F C CP G +G C V+ +ECA
Sbjct: 466 GYTGSRCEADHNECLSQP-CHPGSTCLDLLATFHCLCPPGL----EGQLCEVETNECASA 520
Query: 476 PRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
P + + C + G++C C PGF+ + D+DEC + +C + G+F C C
Sbjct: 521 PCL-NHADCHDLLNGFQCICLPGFSGTRCEE--DIDECRSSPCANGGQCQDQPGAFHCKC 577
Query: 536 PYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGY--RRTSAPQDSENA 592
G+ +G C+ ++DEC+ +P +C ++ G++ C CP G+ + P + N
Sbjct: 578 LPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNL 633
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS 646
C+ C++Q+D + C+ DGS G P ED C G C RS
Sbjct: 634 CQPKQICKDQKDKAN---CLCPDGS------PGCAPPEDNCTC---HHGHCQRS 675
Score = 171 bits (415), Expect = 1e-41
Identities = 169/571 (29%), Positives = 222/571 (38%), Gaps = 101/571 (17%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P G C D P F C C G+E +VDEC PC A C+
Sbjct: 552 IDECRSSP-CANGGQCQDQPGAFHCKCLPGFEGPRCQ---TEVDECL--SDPCPVGASCL 605
Query: 128 NLPGAFECRCPPGYR--------LTPSLDECEDVDECGDQR-----ICDHGDCRNTIGSY 174
+LPGAF C CP G+ P+L C+ C DQ+ +C G
Sbjct: 606 DLPGAFFCLCPSGFTGQLCEVPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPED 663
Query: 175 RCECKPGYTLRENVCRDVD----ECSRP------RPVCRNGTCENLPGAYLCHCDDGFKA 224
C C G+ R + DV EC P GTC P Y C C G+
Sbjct: 664 NCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY-T 722
Query: 225 GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPH 283
GP C + G G C + G + C C P +T G C+ D C +
Sbjct: 723 GPT--CSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT----GPQCQTSTDYC--VSA 774
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVD--RDECKELPYVCAG-GECRNFNGGY 340
PC G +C N G + C C G++ G RC R C + P C C++ G
Sbjct: 775 PCFNGG--TCVNRPGTFSCLCAMGFQ--GPRCEGKLRPSCADSP--CRNRATCQDSPQGP 828
Query: 341 VCECPAGWR-------FDKTA-------AVCVDERKE---LCYDEWEAGRCHRARPLQLA 383
C CP G+ D A + C+ LC W C+ PL
Sbjct: 829 RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNL--PLSSC 886
Query: 384 RPECCCSEGAAWGRYCER---CPAPDSAEFMRICQGGMGRPNLTQD-LDECRVRPDVCVG 439
+ + S+G C C + F G G +L QD ++ C RP C
Sbjct: 887 Q-KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQG--SLCQDHVNPCESRP--CQN 941
Query: 440 GR-CVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGN-GTCSNTRGGYECQCS 496
G C+ + C+C GY DG +C + D C P C N GTC+ GG+ C C
Sbjct: 942 GATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQP--CHNHGTCTPKPGGFHCACP 995
Query: 497 PGFTQGPDQTCV-DVDECAEG--RASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DID 552
PGF C DVDEC + + T CH+ A +F C C G+ G C +ID
Sbjct: 996 PGFV---GLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT----GQWCEVEID 1048
Query: 553 ECVQEPRVCPHACENVVGS---YICKCPEGY 580
C +P CE GS +IC CP+G+
Sbjct: 1049 PCHSQPCFHGGTCEATAGSPLGFICHCPKGF 1079
Score = 167 bits (405), Expect = 2e-40
Identities = 186/634 (29%), Positives = 259/634 (40%), Gaps = 125/634 (19%)
Query: 66 KPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+ ++EC P C GT CH+T FQC C G E C E G P RG +
Sbjct: 193 RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPR----C----ELRAGPCPPRGCS 244
Query: 125 Q---CVNLP---GAFE-CRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRC 176
C +P F C CPPG+ + P +CE + D C + + G C++ + +Y C
Sbjct: 245 NGGTCQLMPEKDSTFHLCLCPPGF-IGP---DCEVNPDNCVSHQCQNGGTCQDGLDTYTC 300
Query: 177 ECKPGYTLRENVCRDVDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVN 234
C +T + DVDEC ++ P CRNG TC+N G++ C C G+ G + +++
Sbjct: 301 LCPETWT-GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW--GGTSCEENLD 357
Query: 235 ECREGGMVCRNGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+C C G C + VGSF C C PG T G C D C L PC D S
Sbjct: 358 DCIAA--TCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMC--LSQPCHGDAQCST 409
Query: 294 TNTNGGYECSCGAGWKLVGRRC-VDRDEC---KELPYVCA-GGECRNFNGGYVCECPAGW 348
G C C G+ G C D DEC ++ P C GG C N G + C CP G+
Sbjct: 410 NPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 467
Query: 349 RFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSA 408
T + C + E C + CH P C + A
Sbjct: 468 ----TGSRCEADHNE-CLSQ----PCH---------PGSTCLDLLA-------------- 495
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCV 467
F +C G+ + +EC P C+ C + F+C C G+ G C
Sbjct: 496 TFHCLCPPGLEGQLCEVETNECASAP--CLNHADCHDLLNGFQCICLPGF----SGTRCE 549
Query: 468 -DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
D DEC P C NG C + G + C+C PGF +GP + +VDEC C
Sbjct: 550 EDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF-EGP-RCQTEVDECLSDPCPVGASCL 605
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRT 583
+ G+F C CP G+ G C ++ C P +C C++ C CP+G
Sbjct: 606 DLPGAFFCLCPSGFT----GQLC-EVPLCA--PNLCQPKQICKDQKDKANCLCPDGSPGC 658
Query: 584 SAPQDS---------ENACE-DIN----ECEEQEDLC------SGGVCINTDGSFLCDCD 623
+ P+D+ ++C D+ ECE + C GG C + C C
Sbjct: 659 APPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 718
Query: 624 AGFEP---SEDGTDCIDRRTGTCYRSLVSGRCEP 654
G+ SE+ T C +G C L G C P
Sbjct: 719 TGYTGPTCSEEMTAC---HSGPC---LNGGSCNP 746
Score = 145 bits (351), Expect = 7e-34
Identities = 153/527 (29%), Positives = 211/527 (40%), Gaps = 105/527 (19%)
Query: 165 GDCRN-TIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCE-------NLPGA-- 213
G C + ++G C+C PG+ L E C+ D C + +C+NG +C+ LP +
Sbjct: 39 GTCLSLSLGQGTCQCAPGF-LGET-CQFPDPCQNAQ-LCQNGGSCQALLPAPLGLPSSPS 95
Query: 214 -----YLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCR-NTVGSFRCECAPGYTLTA 267
+LC C GF G + C + GRC G +C C PG+T
Sbjct: 96 PLTPSFLCTCLPGF-TGERCQAKLEDPCPPS-FCSKRGRCHIQASGRPQCSCMPGWT--- 150
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV-DRDECKELPY 326
G C+ D C +PC G C T +C C G++ G C D +EC + P
Sbjct: 151 -GEQCQLRDFCSA--NPCVNGG--VCLATYPQIQCHCPPGFE--GHACERDVNECFQDPG 203
Query: 327 VCAGG-ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARP 385
C G C N G + C CP G + C E AG C P
Sbjct: 204 PCPKGTSCHNTLGSFQCLCPVG------------QEGPRC--ELRAGPC----------P 239
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN- 444
CS G C+ P DS + +C G P +C V PD CV +C N
Sbjct: 240 PRGCSNGGT----CQLMPEKDSTFHLCLCPPGFIGP-------DCEVNPDNCVSHQCQNG 288
Query: 445 ---TDG--SFRCECPDGYVLAPDGLSCV-DADECALD-PRICGNG-TCSNTRGGYECQCS 496
DG ++ C CP+ + G C D DEC P C NG TC N+ G + C C
Sbjct: 289 GTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
Query: 497 PGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
G+ G ++D+C + C + GSF C CP G G+ C D C+
Sbjct: 345 SGW--GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMCLS 398
Query: 557 EPRVCPHACEN--VVGSYICKCPEGYRRTSAPQDSEN---ACEDINECEEQEDLCSGGVC 611
+P C + GS +C C GY + QD + A + + CE GG C
Sbjct: 399 QPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH------GGSC 452
Query: 612 INTDGSFLCDCDAGFEPSE---DGTDCIDRRT---GTCYRSLVSGRC 652
+NT GSF C C G+ S D +C+ + TC L + C
Sbjct: 453 LNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 499
Score = 121 bits (292), Expect = 1e-26
Identities = 102/340 (30%), Positives = 139/340 (40%), Gaps = 44/340 (12%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGY 141
TC D+P G +C C GY + L +D C+ + PC + C+ +F C C G+
Sbjct: 820 TCQDSPQGPRCLCPTGYTGGSCQTL---MDLCA--QKPCPRNSHCLQTGPSFHCLCLQGW 874
Query: 142 R---LTPSLDECEDV---DECGDQRICDHGD-CRNTIGSYRCECKPGYTLRENVCRD-VD 193
L C+ +C +G C ++ SY C C PG+ + ++C+D V+
Sbjct: 875 TGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF--QGSLCQDHVN 932
Query: 194 EC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRN 250
C SRP C+NG TC P YLC C G+ N +++ C+ C N G C
Sbjct: 933 PCESRP---CQNGATCMAQPSGYLCQCAPGYDG--QNCSKELDACQ--SQPCHNHGTCTP 985
Query: 251 TVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
G F C C PG+ G C DVDEC L PC G +C + + C C G
Sbjct: 986 KPGGFHCACPPGFV----GLRCEGDVDEC--LDQPCHPTGTAACHSLANAFYCQCLPGH- 1038
Query: 310 LVGRRC-VDRDECKELPYVCAGGECRNFNG---GYVCECPAGWRFDKTAAVCVDERKELC 365
G+ C V+ D C P GG C G G++C CP G+ C
Sbjct: 1039 -TGQWCEVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCPKGFE----GPTCSHRAPSCG 1092
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
+ G P P C C G G C PAP
Sbjct: 1093 FHHCHHGGLCLPSPKPGFPPRCACLSGYG-GPDCLTPPAP 1131
Score = 105 bits (251), Expect = 9e-22
Identities = 83/256 (32%), Positives = 114/256 (44%), Gaps = 44/256 (17%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
++ C+ P C+ G TC P+G+ C C GY+ N S +++D C PC C
Sbjct: 931 VNPCESRP--CQNGATCMAQPSGYLCQCAPGYDGQNCS---KELDACQ--SQPCHNHGTC 983
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGD--CRNTIGSYRCECKPGYT 183
PG F C CPPG+ L CE DVDEC DQ G C + ++ C+C PG+T
Sbjct: 984 TPKPGGFHCACPPGF---VGL-RCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT 1039
Query: 184 LRENVCR-DVDECSRPRPVCRNGTCENLPGA---YLCHCDDGFKAGP----NNDCVDVNE 235
C ++D C +P GTCE G+ ++CHC GF+ GP +
Sbjct: 1040 --GQWCEVEIDPC-HSQPCFHGGTCEATAGSPLGFICHCPKGFE-GPTCSHRAPSCGFHH 1095
Query: 236 CREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE---CDELPHPCGRDGNPS 292
C GG+ + + RC C GY G +C C P PC +G S
Sbjct: 1096 CHHGGLCLPSPKPGFPP---RCACLSGY----GGPDCLTPPAPKGCGP-PSPCLYNG--S 1145
Query: 293 CTNTNG----GYECSC 304
C+ T G G+ CSC
Sbjct: 1146 CSETTGLGGPGFRCSC 1161
Score = 96.7 bits (230), Expect = 3e-19
Identities = 119/412 (28%), Positives = 163/412 (39%), Gaps = 91/412 (22%)
Query: 243 CRNG-RCRN-TVGSFRCECAPGYTLTADGRNCRDVDECDE-------------LPHPCGR 287
C NG C + ++G C+CAPG+ G C+ D C LP P G
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFL----GETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 90
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECR-NFNGGYVCECP 345
+PS + + C+C G+ G RC + E P C+ G C +G C C
Sbjct: 91 PSSPSPLTPS--FLCTCLPGF--TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCE-RCPA 404
GW T C + ++ C A P C + G Y + +C
Sbjct: 147 PGW----TGEQC--QLRDFC----------SANP--------CVNGGVCLATYPQIQCHC 182
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDG 463
P E C+ +D++EC P C G C NT GSF+C CP G +G
Sbjct: 183 PPGFE-GHACE---------RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEG 228
Query: 464 LSC-VDADECALDPRICGN-GTC----SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGR 517
C + A C PR C N GTC + C C PGF GPD V+ D C +
Sbjct: 229 PRCELRAGPC--PPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI-GPDCE-VNPDNCVSHQ 284
Query: 518 ASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDEC-VQEPRVCPH--ACENVVGSYI 573
C + ++ C CP + G C D+DEC Q P C + C+N GS+
Sbjct: 285 CQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
C C G+ TS E++++C G CI+ GSF C C G
Sbjct: 341 CVCVSGWGGTSCE-------ENLDDC-IAATCAPGSTCIDRVGSFSCLCPPG 384
Score = 94.3 bits (224), Expect = 2e-18
Identities = 130/513 (25%), Positives = 177/513 (34%), Gaps = 80/513 (15%)
Query: 380 LQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG 439
L L + C C+ G E C PD + ++CQ G L P
Sbjct: 44 LSLGQGTCQCAPGFLG----ETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 99
Query: 440 GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGN-GTCS-NTRGGYECQCSP 497
SF C C G+ G C E P C G C G +C C P
Sbjct: 100 --------SFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMP 147
Query: 498 GFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQ 556
G+T + C D C+ C T +C CP G+ +G C RD++EC Q
Sbjct: 148 GWT---GEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQ 200
Query: 557 EPRVCPH--ACENVVGSYICKCP---EGYR-RTSAPQDSENACEDINECEEQEDLCSG-G 609
+P CP +C N +GS+ C CP EG R A C + C+ + S
Sbjct: 201 DPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFH 260
Query: 610 VCINTDGSFLCDCDAGFE-----PSEDGTDC---IDRRTGTCYRSLVSGRCEPEXXXXXX 661
+C+ G DC+ + ++G C +D T C + C +
Sbjct: 261 LCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECET 320
Query: 662 XXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWG-SECELCPAPGSPARLDLCTAVNLTPX 720
G C C G WG + CE LD C A P
Sbjct: 321 QGPPHCRNGGTCQNSAGSF---HCVCVSG--WGGTSCE--------ENLDDCIAATCAPG 367
Query: 721 XXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP----GLCAP----GRFRCVCGPGYR 772
L D+ C + P C+ G C+C PGY
Sbjct: 368 STCIDRVGSFSCLCPPGRTGLLCHLEDM--CLSQPCHGDAQCSTNPLTGSTLCLCQPGY- 424
Query: 773 PAGEVC-ADVDECAVR---PPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR-DVDEC 825
+G C D+DEC + P PC+ C NT GS++CLC GY G+ C D +EC
Sbjct: 425 -SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNEC 479
Query: 826 ERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
C + ++ C C G E G C
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLE--GQLC 510
Score = 77.4 bits (182), Expect = 2e-13
Identities = 113/396 (28%), Positives = 139/396 (35%), Gaps = 79/396 (19%)
Query: 21 YLCCCSVGHAWGAPCE--ACPPRGSPAHT-ALCGEKPGEYINPVT------NETKPIDEC 71
Y C C G G+ C+ P P A C +P Y+ N +K +D C
Sbjct: 914 YFCHCPPGFQ-GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDAC 972
Query: 72 DIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCR--GMAQCV 127
P C GTC P GF C C G+ C DVDEC PC G A C
Sbjct: 973 QSQP--CHNHGTCTPKPGGFHCACPPGF----VGLRCEGDVDECL--DQPCHPTGTAACH 1024
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGS---YRCECKPGYTL 184
+L AF C+C PG+ T E E +D C Q G C T GS + C C G+
Sbjct: 1025 SLANAFYCQCLPGH--TGQWCEVE-IDPCHSQPCFHGGTCEATAGSPLGFICHCPKGF-- 1079
Query: 185 RENVCRDVDECSRPRPVC------RNGTCENLPGAYL---CHCDDGFKAGPNNDCVDV-- 233
+ CS P C G C P C C G+ GP DC+
Sbjct: 1080 ------EGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGY-GGP--DCLTPPA 1130
Query: 234 -NECREGGMVCRNGRCRNTVG----SFRCEC---APGYTLTADG-RNCRDVDECDELPHP 284
C NG C T G FRC C +PG G + C
Sbjct: 1131 PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAG 1190
Query: 285 CGRDGNPSCTNTNGGYECSCGAG--WKLVGR--RCVDRDECKELPYVCAGGECRNFNGGY 340
C G N +GG +CS G WK RC + C EC F+G Y
Sbjct: 1191 CSGPGG----NWDGG-DCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECL-FDG-Y 1243
Query: 341 VCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHR 376
CE P C + C+D + G C +
Sbjct: 1244 DCETPPA---------CTPAYDQYCHDHFHNGHCEK 1270
Score = 71.7 bits (168), Expect = 1e-11
Identities = 108/408 (26%), Positives = 142/408 (34%), Gaps = 80/408 (19%)
Query: 472 CALDPRICGNG-TC-SNTRGGYECQCSPGF----TQGPDQTCVDVDECAEGRASCTFRCH 525
C P C NG TC S + G CQC+PGF Q PD C + C G SC
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNG-GSCQALLP 85
Query: 526 NTAG----------SFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH--ACE-NVVGSY 572
G SF CTC G+ G C+ E P C C G
Sbjct: 86 APLGLPSSPSPLTPSFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRP 141
Query: 573 ICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDG 632
C C G+ T + C N C +GGVC+ T C C GFE G
Sbjct: 142 QCSCMPGW--TGEQCQLRDFC-SANPC------VNGGVCLATYPQIQCHCPPGFE----G 188
Query: 633 TDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAA 692
C +R C++ G C P+ +A C G +
Sbjct: 189 HAC-ERDVNECFQD--PGPC-PKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCS 244
Query: 693 WGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECA 752
G C+L P S L LC + P D + D C
Sbjct: 245 NGGTCQLMPEKDSTFHLCLCPPGFIGP-----------------------DCEVNPDNCV 281
Query: 753 AIP----GLCAPG--RFRCVCGPGYRPAGEVCADVDECAVR-PPPCDQ--LCHNTDGSYD 803
+ G C G + C+C P + DVDEC + PP C C N+ GS+
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLC-PETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340
Query: 804 CLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDG 850
C+C +G+ G +C + +D+C T C + GS+ C C G
Sbjct: 341 CVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG 384
Score = 62.5 bits (145), Expect = 6e-09
Identities = 39/111 (35%), Positives = 53/111 (47%), Gaps = 14/111 (12%)
Query: 747 DVDECAAIP----GLCA--PGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D+DEC + P G C PG F C C PG+ G C +VDEC P P C +
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFE--GPRCQTEVDECLSDPCPVGASCLDLP 608
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
G++ CLC +G+ G C +V C + +QIC + + C C DG
Sbjct: 609 GAFFCLCPSGF----TGQLC-EVPLCAPNLCQPKQICKDQKDKANCLCPDG 654
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 18/117 (15%)
Query: 746 ADVDECAAIPGLCAPGR--------FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCH 796
AD +EC + P C PG F C+C PG G++C + +ECA P CH
Sbjct: 474 ADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE--GQLCEVETNECASAPCLNHADCH 529
Query: 797 NTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+ + C+C G+ G C D+DEC C + G++ C C G+E
Sbjct: 530 DLLNGFQCICLPGFS----GTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE 582
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/113 (31%), Positives = 54/113 (47%), Gaps = 14/113 (12%)
Query: 747 DVDECAAIPGL----CAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+ +ECA+ P L C F+C+C PG+ +G C D+DEC P C +
Sbjct: 513 ETNECASAPCLNHADCHDLLNGFQCICLPGF--SGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G++ C C G+E G C+ +VDEC D C + G++ C C G+
Sbjct: 571 GAFHCKCLPGFE----GPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGF 619
Score = 54.4 bits (125), Expect = 2e-06
Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 10/109 (9%)
Query: 747 DVDECAAIPGLCAPG--RFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYD 803
DV GLC + C C PG++ G +C D V+ C RP C Y
Sbjct: 896 DVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHVNPCESRPCQNGATCMAQPSGYL 953
Query: 804 CLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C C GY DG NC +++D C+ C+ G + C+C G+
Sbjct: 954 CQCAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGF 998
Score = 48.4 bits (110), Expect = 1e-04
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 8/97 (8%)
Query: 757 LCAPGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 815
L PG F C+C PGY G C AD +EC +P C + ++ CLC G E
Sbjct: 453 LNTPGSFNCLCPPGY--TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE---- 506
Query: 816 GANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C + +EC C + ++C C G+
Sbjct: 507 GQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 543
Score = 42.3 bits (95), Expect = 0.007
Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 10/101 (9%)
Query: 749 DECAAIPGLCAPGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCR 807
D C G C R CVC G+ G C A++ C P C+ Y+C C
Sbjct: 663 DNCTCHHGHCQ--RSSCVCDVGW--TGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 718
Query: 808 TGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSC 847
TGY G C ++ C C+ + G Y C+C
Sbjct: 719 TGY----TGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 755
Score = 40.3 bits (90), Expect = 0.028
Identities = 26/101 (25%), Positives = 37/101 (36%), Gaps = 7/101 (6%)
Query: 759 APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
+PG + C C P + G C D C P C N G++ CLC G++
Sbjct: 747 SPGGYYCTCPPSH--TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEG 804
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
R C + C ++ C C GY G +C
Sbjct: 805 KLR--PSCADSPCRNRATCQDSPQGPRCLCPTGY--TGGSC 841
Score = 39.9 bits (89), Expect = 0.038
Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 18/106 (16%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DV 822
RC+C GY G +D CA +P P + C T S+ CLC G+ G C +
Sbjct: 829 RCLCPTGYT-GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGW----TGPLCNLPL 883
Query: 823 DECERD--------THTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
C++ + C +C ++ SY C C G++ G C
Sbjct: 884 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLC 927
Score = 35.1 bits (77), Expect = 1.1
Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 14/73 (19%)
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDG 850
LC ++ SY C C G++ G+ C+D V+ CE + CQ C Y C C G
Sbjct: 906 LCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPG 959
Query: 851 YE-----KRGDAC 858
Y+ K DAC
Sbjct: 960 YDGQNCSKELDAC 972
>U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.
Length = 1999
Score = 193 bits (470), Expect = 3e-48
Identities = 167/563 (29%), Positives = 242/563 (42%), Gaps = 80/563 (14%)
Query: 92 CGCDHGYEHDNTSHLCRDVDEC---SWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD 148
C C GY T H +D+DEC G PC C+N PG+F C CPPGY T S
Sbjct: 417 CLCQPGYSGP-TCH--QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGS-- 469
Query: 149 ECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGT 206
CE D +EC Q C + + ++ C C PG L +C + +EC+ P +
Sbjct: 470 RCEADHNECLSQPCHPGSTCLDLLATFHCLCPPG--LEGQLCEVETNECA-SAPCLNHAD 526
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTL 265
C +L + C C GF + D++ECR C N G+C++ G+F C+C PG+
Sbjct: 527 CHDLLNGFQCICLPGFSGTRCEE--DIDECRSS--PCANGGQCQDQPGAFHCKCLPGF-- 580
Query: 266 TADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKEL 324
+G C+ +VDEC P P G SC + G + C C +G+ G+ C + C
Sbjct: 581 --EGPRCQTEVDECLSDPCPVG----ASCLDLPGAFFCLCPSGF--TGQLC-EVPLC--A 629
Query: 325 PYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRAR---PL 380
P +C + C++ C CP D + E C+ G C R+ +
Sbjct: 630 PNLCQPKQICKDQKDKANCLCP-----DGSPGCAPPEDNCTCHH----GHCQRSSCVCDV 680
Query: 381 QLARPEC------CCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP 434
PEC C S A G C P + + C G P ++++ C P
Sbjct: 681 GWTGPECEAELGGCISAPCAHGGTC----YPQPSGYNCTCPTGYTGPTCSEEMTACHSGP 736
Query: 435 DVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYE 492
C+ GG C + G + C CP + G C D C P G GTC N G +
Sbjct: 737 --CLNGGSCNPSPGGYYCTCPPSHT----GPQCQTSTDYCVSAPCFNG-GTCVNRPGTFS 789
Query: 493 CQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI- 551
C C+ GF QGP CA+ C ++ RC CP GY G C+ +
Sbjct: 790 CLCAMGF-QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYT----GGSCQTLM 844
Query: 552 DECVQEPRVCPH--ACENVVGSYICKCPEGYR--RTSAPQDSENACEDINECEEQEDLC- 606
D C Q+P CP C S+ C C +G+ + P S +++ + LC
Sbjct: 845 DLCAQKP--CPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAA-LSQGIDVSSLCH 901
Query: 607 SGGVCINTDGSFLCDCDAGFEPS 629
+GG+C+++ S+ C C GF+ S
Sbjct: 902 NGGLCVDSGPSYFCHCPPGFQGS 924
Score = 186 bits (454), Expect = 2e-46
Identities = 191/641 (29%), Positives = 255/641 (39%), Gaps = 118/641 (18%)
Query: 33 APCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKP----GTCHDTPT 88
A C P GS LC +PG Y P ++ +DEC + Q P G+C +TP
Sbjct: 404 AQCSTNPLTGS----TLCLCQPG-YSGPTCHQD--LDECLMAQQGPSPCEHGGSCLNTPG 456
Query: 89 GFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
F C C GY T C D +EC PC + C++L F C CPPG L L
Sbjct: 457 SFNCLCPPGY----TGSRCEADHNECL--SQPCHPGSTCLDLLATFHCLCPPG--LEGQL 508
Query: 148 DECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTC 207
E E +EC +H DC + + ++C C PG++ D+DEC R P G C
Sbjct: 509 CEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS-GTRCEEDIDEC-RSSPCANGGQC 565
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYT-- 264
++ PGA+ C C GF+ GP +V+EC C G C + G+F C C G+T
Sbjct: 566 QDQPGAFHCKCLPGFE-GPRCQ-TEVDECLSD--PCPVGASCLDLPGAFFCLCPSGFTGQ 621
Query: 265 ----------LTADGRNCRDVDECDELPHPCGRDG----NPSCTNTNGGYE---CSCGAG 307
L + C+D + P G G +CT +G + C C G
Sbjct: 622 LCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVG 681
Query: 308 WKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
W G C + C P CA GG C GY C CP G+ T C E C
Sbjct: 682 W--TGPECEAELGGCISAP--CAHGGTCYPQPSGYNCTCPTGY----TGPTC-SEEMTAC 732
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
+ +G C L C S G G YC CP + P
Sbjct: 733 H----SGPC-------LNGGSCNPSPG---GYYC-TCPPSHTG------------PQCQT 765
Query: 426 DLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVD--ADECALDPRICGN- 481
D C P C GG CVN G+F C C G+ G C CA P C N
Sbjct: 766 STDYCVSAP--CFNGGTCVNRPGTFSCLCAMGF----QGPRCEGKLRPSCADSP--CRNR 817
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA- 540
TC ++ G C C G+T G QT +D+ CA+ C T SF C C G+
Sbjct: 818 ATCQDSPQGPRCLCPTGYTGGSCQTLMDL--CAQKPCPRNSHCLQTGPSFHCLCLQGWTG 875
Query: 541 ----VAADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENACE 594
+ + + + +C + C + SY C CP G+ + S QD N CE
Sbjct: 876 PLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF-QGSLCQDHVNPCE 934
Query: 595 DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
C+ +G C+ +LC C G+ DG +C
Sbjct: 935 S-RPCQ------NGATCMAQPSGYLCQCAPGY----DGQNC 964
Score = 177 bits (432), Expect = 1e-43
Identities = 182/654 (27%), Positives = 267/654 (40%), Gaps = 107/654 (16%)
Query: 21 YLCCCSVGHAWGAPCEA-----CPP----RGSPAHTALCGEKPGEYINPVTNETKPI-DE 70
+LC C G G C+A CPP + H G + T E + D
Sbjct: 100 FLCTCLPGFT-GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDF 158
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNL 129
C P + G C T QC C G+E H C RDV+EC PC C N
Sbjct: 159 CSANPCV-NGGVCLATYPQIQCHCPPGFE----GHACERDVNECFQDPGPCPKGTSCHNT 213
Query: 130 PGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCR----NTIGSYRCECKPGYTL 184
G+F+C CP G P CE C + + G C+ + C C PG+ +
Sbjct: 214 LGSFQCLCPVGQE-GP---RCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGF-I 268
Query: 185 RENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCV-DVNECR-EGGM 241
+ D C + C+NG TC++ Y C C + + DC DV+EC +G
Sbjct: 269 GPGCEVNPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGW---DCSEDVDECEAQGPP 323
Query: 242 VCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGG 299
CRNG C+N+ GSF C C G+ G +C + +D+C + C +C + G
Sbjct: 324 HCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDC--IAATCA--PGSTCIDRVGS 375
Query: 300 YECSCGAGWKLVGRRCVDRDECKELPYVCAG-GECRN--FNGGYVCECPAGWRFDKTAAV 356
+ C C G G C D C P C G +C G +C C G+ +
Sbjct: 376 FSCLCPPG--RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTLCLCQPGY----SGPT 427
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
C + E C A+ Q P C G + C P F +C
Sbjct: 428 CHQDLDE----------CLMAQ--QGPSP---CEHGGS----CLNTP----GSFNCLCPP 464
Query: 417 GMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALD 475
G D +EC +P G C++ +F C CP G +G C V+ +ECA
Sbjct: 465 GYTGSRCEADHNECLSQP-CHPGSTCLDLLATFHCLCPPGL----EGQLCEVETNECASA 519
Query: 476 PRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
P + + C + G++C C PGF+ + D+DEC + +C + G+F C C
Sbjct: 520 PCL-NHADCHDLLNGFQCICLPGFSGTRCEE--DIDECRSSPCANGGQCQDQPGAFHCKC 576
Query: 536 PYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGY--RRTSAPQDSENA 592
G+ +G C+ ++DEC+ +P +C ++ G++ C CP G+ + P + N
Sbjct: 577 LPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNL 632
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS 646
C+ C++Q+D + C+ DGS G P ED C G C RS
Sbjct: 633 CQPKQICKDQKDKAN---CLCPDGS------PGCAPPEDNCTC---HHGHCQRS 674
Score = 171 bits (415), Expect = 1e-41
Identities = 169/571 (29%), Positives = 222/571 (38%), Gaps = 101/571 (17%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P G C D P F C C G+E +VDEC PC A C+
Sbjct: 551 IDECRSSP-CANGGQCQDQPGAFHCKCLPGFEGPRCQ---TEVDECL--SDPCPVGASCL 604
Query: 128 NLPGAFECRCPPGYR--------LTPSLDECEDVDECGDQR-----ICDHGDCRNTIGSY 174
+LPGAF C CP G+ P+L C+ C DQ+ +C G
Sbjct: 605 DLPGAFFCLCPSGFTGQLCEVPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPED 662
Query: 175 RCECKPGYTLRENVCRDVD----ECSRP------RPVCRNGTCENLPGAYLCHCDDGFKA 224
C C G+ R + DV EC P GTC P Y C C G+
Sbjct: 663 NCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY-T 721
Query: 225 GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPH 283
GP C + G G C + G + C C P +T G C+ D C +
Sbjct: 722 GPT--CSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT----GPQCQTSTDYC--VSA 773
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVD--RDECKELPYVCAG-GECRNFNGGY 340
PC G +C N G + C C G++ G RC R C + P C C++ G
Sbjct: 774 PCFNGG--TCVNRPGTFSCLCAMGFQ--GPRCEGKLRPSCADSP--CRNRATCQDSPQGP 827
Query: 341 VCECPAGWR-------FDKTA-------AVCVDERKE---LCYDEWEAGRCHRARPLQLA 383
C CP G+ D A + C+ LC W C+ PL
Sbjct: 828 RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNL--PLSSC 885
Query: 384 RPECCCSEGAAWGRYCER---CPAPDSAEFMRICQGGMGRPNLTQD-LDECRVRPDVCVG 439
+ + S+G C C + F G G +L QD ++ C RP C
Sbjct: 886 Q-KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQG--SLCQDHVNPCESRP--CQN 940
Query: 440 GR-CVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGN-GTCSNTRGGYECQCS 496
G C+ + C+C GY DG +C + D C P C N GTC+ GG+ C C
Sbjct: 941 GATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQP--CHNHGTCTPKPGGFHCACP 994
Query: 497 PGFTQGPDQTCV-DVDECAEG--RASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DID 552
PGF C DVDEC + + T CH+ A +F C C G+ G C +ID
Sbjct: 995 PGFV---GLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT----GQWCEVEID 1047
Query: 553 ECVQEPRVCPHACENVVGS---YICKCPEGY 580
C +P CE GS +IC CP+G+
Sbjct: 1048 PCHSQPCFHGGTCEATAGSPLGFICHCPKGF 1078
Score = 166 bits (403), Expect = 3e-40
Identities = 186/634 (29%), Positives = 258/634 (40%), Gaps = 125/634 (19%)
Query: 66 KPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+ ++EC P C GT CH+T FQC C G E C E G P RG +
Sbjct: 192 RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPR----C----ELRAGPCPPRGCS 243
Query: 125 Q---CVNLP---GAFE-CRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRC 176
C +P F C CPPG+ + P CE + D C + + G C++ + +Y C
Sbjct: 244 NGGTCQLMPEKDSTFHLCLCPPGF-IGPG---CEVNPDNCVSHQCQNGGTCQDGLDTYTC 299
Query: 177 ECKPGYTLRENVCRDVDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVN 234
C +T + DVDEC ++ P CRNG TC+N G++ C C G+ G + +++
Sbjct: 300 LCPETWT-GWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGW--GGTSCEENLD 356
Query: 235 ECREGGMVCRNGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+C C G C + VGSF C C PG T G C D C L PC D S
Sbjct: 357 DCIAA--TCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMC--LSQPCHGDAQCST 408
Query: 294 TNTNGGYECSCGAGWKLVGRRC-VDRDEC---KELPYVCA-GGECRNFNGGYVCECPAGW 348
G C C G+ G C D DEC ++ P C GG C N G + C CP G+
Sbjct: 409 NPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 466
Query: 349 RFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSA 408
T + C + E C + CH P C + A
Sbjct: 467 ----TGSRCEADHNE-CLSQ----PCH---------PGSTCLDLLA-------------- 494
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCV 467
F +C G+ + +EC P C+ C + F+C C G+ G C
Sbjct: 495 TFHCLCPPGLEGQLCEVETNECASAP--CLNHADCHDLLNGFQCICLPGF----SGTRCE 548
Query: 468 -DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
D DEC P C NG C + G + C+C PGF +GP + +VDEC C
Sbjct: 549 EDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF-EGP-RCQTEVDECLSDPCPVGASCL 604
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRT 583
+ G+F C CP G+ G C ++ C P +C C++ C CP+G
Sbjct: 605 DLPGAFFCLCPSGFT----GQLC-EVPLCA--PNLCQPKQICKDQKDKANCLCPDGSPGC 657
Query: 584 SAPQDS---------ENACE-DIN----ECEEQEDLC------SGGVCINTDGSFLCDCD 623
+ P+D+ ++C D+ ECE + C GG C + C C
Sbjct: 658 APPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 717
Query: 624 AGFEP---SEDGTDCIDRRTGTCYRSLVSGRCEP 654
G+ SE+ T C +G C L G C P
Sbjct: 718 TGYTGPTCSEEMTAC---HSGPC---LNGGSCNP 745
Score = 145 bits (352), Expect = 5e-34
Identities = 154/527 (29%), Positives = 211/527 (40%), Gaps = 105/527 (19%)
Query: 165 GDCRN-TIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCE-------NLPGA-- 213
G C + ++G C+C PG+ L E C+ D C + +C+NG +C+ LP +
Sbjct: 38 GTCLSLSLGQGTCQCAPGF-LGET-CQFPDPCQNAQ-LCQNGGSCQALLPAPLGLPSSPS 94
Query: 214 -----YLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCR-NTVGSFRCECAPGYTLTA 267
+LC C GF G + C + GRC G +C C PG+T
Sbjct: 95 PLTPSFLCTCLPGF-TGERCQAKLEDPCPPS-FCSKRGRCHIQASGRPQCSCMPGWT--- 149
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV-DRDECKELPY 326
G C+ D C +PC G C T +C C G++ G C D +EC + P
Sbjct: 150 -GEQCQLRDFCSA--NPCVNGG--VCLATYPQIQCHCPPGFE--GHACERDVNECFQDPG 202
Query: 327 VCAGG-ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARP 385
C G C N G + C CP G + C E AG C P
Sbjct: 203 PCPKGTSCHNTLGSFQCLCPVG------------QEGPRC--ELRAGPC----------P 238
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN- 444
CS G C+ P DS + +C G P C V PD CV +C N
Sbjct: 239 PRGCSNGGT----CQLMPEKDSTFHLCLCPPGFIGPG-------CEVNPDNCVSHQCQNG 287
Query: 445 ---TDG--SFRCECPDGYVLAPDGLSCV-DADEC-ALDPRICGNG-TCSNTRGGYECQCS 496
DG ++ C CP+ + G C D DEC A P C NG TC N+ G + C C
Sbjct: 288 GTCQDGLDTYTCLCPETWT----GWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCV 343
Query: 497 PGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
G+ G ++D+C + C + GSF C CP G G+ C D C+
Sbjct: 344 SGW--GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMCLS 397
Query: 557 EPRVCPHACEN--VVGSYICKCPEGYRRTSAPQDSEN---ACEDINECEEQEDLCSGGVC 611
+P C + GS +C C GY + QD + A + + CE GG C
Sbjct: 398 QPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH------GGSC 451
Query: 612 INTDGSFLCDCDAGFEPSE---DGTDCIDRRT---GTCYRSLVSGRC 652
+NT GSF C C G+ S D +C+ + TC L + C
Sbjct: 452 LNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 498
Score = 121 bits (292), Expect = 1e-26
Identities = 102/340 (30%), Positives = 139/340 (40%), Gaps = 44/340 (12%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGY 141
TC D+P G +C C GY + L +D C+ + PC + C+ +F C C G+
Sbjct: 819 TCQDSPQGPRCLCPTGYTGGSCQTL---MDLCA--QKPCPRNSHCLQTGPSFHCLCLQGW 873
Query: 142 R---LTPSLDECEDV---DECGDQRICDHGD-CRNTIGSYRCECKPGYTLRENVCRD-VD 193
L C+ +C +G C ++ SY C C PG+ + ++C+D V+
Sbjct: 874 TGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF--QGSLCQDHVN 931
Query: 194 EC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRN 250
C SRP C+NG TC P YLC C G+ N +++ C+ C N G C
Sbjct: 932 PCESRP---CQNGATCMAQPSGYLCQCAPGYDG--QNCSKELDACQ--SQPCHNHGTCTP 984
Query: 251 TVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
G F C C PG+ G C DVDEC L PC G +C + + C C G
Sbjct: 985 KPGGFHCACPPGFV----GLRCEGDVDEC--LDQPCHPTGTAACHSLANAFYCQCLPGH- 1037
Query: 310 LVGRRC-VDRDECKELPYVCAGGECRNFNG---GYVCECPAGWRFDKTAAVCVDERKELC 365
G+ C V+ D C P GG C G G++C CP G+ C
Sbjct: 1038 -TGQWCEVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCPKGFE----GPTCSHRAPSCG 1091
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
+ G P P C C G G C PAP
Sbjct: 1092 FHHCHHGGLCLPSPKPGFPPRCACLSGYG-GPDCLTPPAP 1130
Score = 105 bits (251), Expect = 9e-22
Identities = 83/256 (32%), Positives = 114/256 (44%), Gaps = 44/256 (17%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
++ C+ P C+ G TC P+G+ C C GY+ N S +++D C PC C
Sbjct: 930 VNPCESRP--CQNGATCMAQPSGYLCQCAPGYDGQNCS---KELDACQ--SQPCHNHGTC 982
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGD--CRNTIGSYRCECKPGYT 183
PG F C CPPG+ L CE DVDEC DQ G C + ++ C+C PG+T
Sbjct: 983 TPKPGGFHCACPPGF---VGL-RCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT 1038
Query: 184 LRENVCR-DVDECSRPRPVCRNGTCENLPGA---YLCHCDDGFKAGP----NNDCVDVNE 235
C ++D C +P GTCE G+ ++CHC GF+ GP +
Sbjct: 1039 --GQWCEVEIDPC-HSQPCFHGGTCEATAGSPLGFICHCPKGFE-GPTCSHRAPSCGFHH 1094
Query: 236 CREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE---CDELPHPCGRDGNPS 292
C GG+ + + RC C GY G +C C P PC +G S
Sbjct: 1095 CHHGGLCLPSPKPGFPP---RCACLSGY----GGPDCLTPPAPKGCGP-PSPCLYNG--S 1144
Query: 293 CTNTNG----GYECSC 304
C+ T G G+ CSC
Sbjct: 1145 CSETTGLGGPGFRCSC 1160
Score = 96.3 bits (229), Expect = 4e-19
Identities = 126/446 (28%), Positives = 173/446 (38%), Gaps = 85/446 (19%)
Query: 243 CRNG-RCRN-TVGSFRCECAPGYTLTADGRNCRDVDECDE-------------LPHPCGR 287
C NG C + ++G C+CAPG+ G C+ D C LP P G
Sbjct: 34 CANGGTCLSLSLGQGTCQCAPGFL----GETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 89
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECR-NFNGGYVCECP 345
+PS + + C+C G+ G RC + E P C+ G C +G C C
Sbjct: 90 PSSPSPLTPS--FLCTCLPGF--TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 145
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARP--ECCCSEGAAWGRYCER-- 401
GW T C + ++ C A C P +C C G G CER
Sbjct: 146 PGW----TGEQC--QLRDFC----SANPCVNGGVCLATYPQIQCHCPPGFE-GHACERDV 194
Query: 402 ---------CPAPDS-----AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRC---VN 444
CP S F +C G P C R GG C
Sbjct: 195 NECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPR-GCSNGGTCQLMPE 253
Query: 445 TDGSFR-CECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG 502
D +F C CP G++ G C V+ D C + + GTC + Y C C +T G
Sbjct: 254 KDSTFHLCLCPPGFI----GPGCEVNPDNC-VSHQCQNGGTCQDGLDTYTCLCPETWT-G 307
Query: 503 PDQTCVDVDEC-AEGRASCT--FRCHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQEP 558
D DVDEC A+G C C N+AGSF C C G+ G C + +D+C+
Sbjct: 308 WD-CSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWG----GTSCEENLDDCIAAT 362
Query: 559 RVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSF 618
C + VGS+ C CP G RT E+ C +++ + CS GS
Sbjct: 363 CAPGSTCIDRVGSFSCLCPPG--RTGLLCHLEDMC--LSQPCHGDAQCSTN---PLTGST 415
Query: 619 LCDCDAGFE-PS--EDGTDCIDRRTG 641
LC C G+ P+ +D +C+ + G
Sbjct: 416 LCLCQPGYSGPTCHQDLDECLMAQQG 441
Score = 77.4 bits (182), Expect = 2e-13
Identities = 113/396 (28%), Positives = 139/396 (35%), Gaps = 79/396 (19%)
Query: 21 YLCCCSVGHAWGAPCE--ACPPRGSPAHT-ALCGEKPGEYINPVT------NETKPIDEC 71
Y C C G G+ C+ P P A C +P Y+ N +K +D C
Sbjct: 913 YFCHCPPGFQ-GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDAC 971
Query: 72 DIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCR--GMAQCV 127
P C GTC P GF C C G+ C DVDEC PC G A C
Sbjct: 972 QSQP--CHNHGTCTPKPGGFHCACPPGF----VGLRCEGDVDECL--DQPCHPTGTAACH 1023
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGS---YRCECKPGYTL 184
+L AF C+C PG+ T E E +D C Q G C T GS + C C G+
Sbjct: 1024 SLANAFYCQCLPGH--TGQWCEVE-IDPCHSQPCFHGGTCEATAGSPLGFICHCPKGF-- 1078
Query: 185 RENVCRDVDECSRPRPVC------RNGTCENLPGAYL---CHCDDGFKAGPNNDCVDV-- 233
+ CS P C G C P C C G+ GP DC+
Sbjct: 1079 ------EGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGY-GGP--DCLTPPA 1129
Query: 234 -NECREGGMVCRNGRCRNTVG----SFRCEC---APGYTLTADG-RNCRDVDECDELPHP 284
C NG C T G FRC C +PG G + C
Sbjct: 1130 PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAG 1189
Query: 285 CGRDGNPSCTNTNGGYECSCGAG--WKLVGR--RCVDRDECKELPYVCAGGECRNFNGGY 340
C G N +GG +CS G WK RC + C EC F+G Y
Sbjct: 1190 CSGPGG----NWDGG-DCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECL-FDG-Y 1242
Query: 341 VCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHR 376
CE P C + C+D + G C +
Sbjct: 1243 DCETPPA---------CTPAYDQYCHDHFHNGHCEK 1269
Score = 67.3 bits (157), Expect = 2e-10
Identities = 106/404 (26%), Positives = 136/404 (33%), Gaps = 72/404 (17%)
Query: 472 CALDPRICGNG-TC-SNTRGGYECQCSPGFT----QGPDQTCVDVDECAEGRASCTFRCH 525
C P C NG TC S + G CQC+PGF Q PD C + C G SC
Sbjct: 27 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDP-CQNAQLCQNG-GSCQALLP 84
Query: 526 NTAG----------SFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA--CE-NVVGSY 572
G SF CTC G+ G C+ E P C C G
Sbjct: 85 APLGLPSSPSPLTPSFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRP 140
Query: 573 ICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDG 632
C C G+ T + C N C +GGVC+ T C C GFE G
Sbjct: 141 QCSCMPGW--TGEQCQLRDFCS-ANPC------VNGGVCLATYPQIQCHCPPGFE----G 187
Query: 633 TDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAA 692
C +R C++ G C P+ QC C +G
Sbjct: 188 HAC-ERDVNECFQD--PGPC-PKGTSCHNTLGSF-----------------QCLCPVGQE 226
Query: 693 WGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECA 752
G CEL P P L P +C
Sbjct: 227 -GPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPDNCVSHQCQ 285
Query: 753 AIPGLCAPG--RFRCVCGPGYRPAGEVCADVDECAVRPPP-CDQ--LCHNTDGSYDCLCR 807
G C G + C+C P + DVDEC + PP C C N+ GS+ C+C
Sbjct: 286 N-GGTCQDGLDTYTCLC-PETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCV 343
Query: 808 TGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDG 850
+G+ G +C + +D+C T C + GS+ C C G
Sbjct: 344 SGW----GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG 383
Score = 62.5 bits (145), Expect = 6e-09
Identities = 39/111 (35%), Positives = 53/111 (47%), Gaps = 14/111 (12%)
Query: 747 DVDECAAIP----GLCA--PGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D+DEC + P G C PG F C C PG+ G C +VDEC P P C +
Sbjct: 550 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFE--GPRCQTEVDECLSDPCPVGASCLDLP 607
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
G++ CLC +G+ G C +V C + +QIC + + C C DG
Sbjct: 608 GAFFCLCPSGF----TGQLC-EVPLCAPNLCQPKQICKDQKDKANCLCPDG 653
Score = 58.4 bits (135), Expect = 1e-07
Identities = 37/97 (38%), Positives = 47/97 (48%), Gaps = 9/97 (9%)
Query: 759 APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
A GR +C C PG+ GE C D C+ P +C T C C G+E G
Sbjct: 136 ASGRPQCSCMPGW--TGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFE----GHA 189
Query: 819 C-RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE 852
C RDV+EC +D C + C NT GS++C C G E
Sbjct: 190 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE 226
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 18/117 (15%)
Query: 746 ADVDECAAIPGLCAPGR--------FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCH 796
AD +EC + P C PG F C+C PG G++C + +ECA P CH
Sbjct: 473 ADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE--GQLCEVETNECASAPCLNHADCH 528
Query: 797 NTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+ + C+C G+ G C D+DEC C + G++ C C G+E
Sbjct: 529 DLLNGFQCICLPGFS----GTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE 581
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/113 (31%), Positives = 54/113 (47%), Gaps = 14/113 (12%)
Query: 747 DVDECAAIPGL----CAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+ +ECA+ P L C F+C+C PG+ +G C D+DEC P C +
Sbjct: 512 ETNECASAPCLNHADCHDLLNGFQCICLPGF--SGTRCEEDIDECRSSPCANGGQCQDQP 569
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G++ C C G+E G C+ +VDEC D C + G++ C C G+
Sbjct: 570 GAFHCKCLPGFE----GPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGF 618
Score = 57.2 bits (132), Expect = 2e-07
Identities = 37/105 (35%), Positives = 49/105 (46%), Gaps = 15/105 (14%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDECAVR---PPPCDQ--LCHNTDGSYDCLCRTGYELDE 814
G C+C PGY +G C D+DEC + P PC+ C NT GS++CLC GY
Sbjct: 413 GSTLCLCQPGY--SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY---- 466
Query: 815 DGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
G+ C D +EC C + ++ C C G E G C
Sbjct: 467 TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE--GQLC 509
Score = 54.4 bits (125), Expect = 2e-06
Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 10/109 (9%)
Query: 747 DVDECAAIPGLCAPG--RFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYD 803
DV GLC + C C PG++ G +C D V+ C RP C Y
Sbjct: 895 DVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHVNPCESRPCQNGATCMAQPSGYL 952
Query: 804 CLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C C GY DG NC +++D C+ C+ G + C+C G+
Sbjct: 953 CQCAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGF 997
Score = 51.2 bits (117), Expect = 2e-05
Identities = 38/117 (32%), Positives = 52/117 (44%), Gaps = 20/117 (17%)
Query: 749 DECAAIP----GLCAPG--RFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTD 799
D C+A P G+C + +C C PG+ G C DV+EC P PC + CHNT
Sbjct: 157 DFCSANPCVNGGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSCHNTL 214
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECE----RDTHTCQQICSNTEGSYECSCEDGY 851
GS+ CLC G ++G C C + TCQ + + C C G+
Sbjct: 215 GSFQCLCPVG----QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGF 267
Score = 48.4 bits (110), Expect = 1e-04
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 8/97 (8%)
Query: 757 LCAPGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 815
L PG F C+C PGY G C AD +EC +P C + ++ CLC G E
Sbjct: 452 LNTPGSFNCLCPPGY--TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE---- 505
Query: 816 GANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C + +EC C + ++C C G+
Sbjct: 506 GQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 542
Score = 46.8 bits (106), Expect = 3e-04
Identities = 33/110 (30%), Positives = 46/110 (41%), Gaps = 19/110 (17%)
Query: 748 VDECAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCR 807
+D + LC PGR +C + C +C+ P GS CLC+
Sbjct: 370 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNP---------LTGSTLCLCQ 420
Query: 808 TGYELDEDGANC-RDVDEC---ERDTHTCQQ--ICSNTEGSYECSCEDGY 851
GY G C +D+DEC ++ C+ C NT GS+ C C GY
Sbjct: 421 PGY----SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 466
Score = 43.6 bits (98), Expect = 0.003
Identities = 30/92 (32%), Positives = 42/92 (45%), Gaps = 11/92 (11%)
Query: 765 CVCGPGY-RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDV 822
C+C PG+ P EV + D C C + +Y CLC + G +C DV
Sbjct: 261 CLCPPGFIGPGCEV--NPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT----GWDCSEDV 314
Query: 823 DECE-RDTHTCQQ--ICSNTEGSYECSCEDGY 851
DECE + C+ C N+ GS+ C C G+
Sbjct: 315 DECEAQGPPHCRNGGTCQNSAGSFHCVCVSGW 346
Score = 42.3 bits (95), Expect = 0.007
Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 10/101 (9%)
Query: 749 DECAAIPGLCAPGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCR 807
D C G C R CVC G+ G C A++ C P C+ Y+C C
Sbjct: 662 DNCTCHHGHCQ--RSSCVCDVGW--TGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 717
Query: 808 TGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSC 847
TGY G C ++ C C+ + G Y C+C
Sbjct: 718 TGY----TGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 754
Score = 40.3 bits (90), Expect = 0.028
Identities = 26/101 (25%), Positives = 37/101 (36%), Gaps = 7/101 (6%)
Query: 759 APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
+PG + C C P + G C D C P C N G++ CLC G++
Sbjct: 746 SPGGYYCTCPPSH--TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEG 803
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
R C + C ++ C C GY G +C
Sbjct: 804 KLR--PSCADSPCRNRATCQDSPQGPRCLCPTGY--TGGSC 840
Score = 39.9 bits (89), Expect = 0.038
Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 18/106 (16%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DV 822
RC+C GY G +D CA +P P + C T S+ CLC G+ G C +
Sbjct: 828 RCLCPTGYT-GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGW----TGPLCNLPL 882
Query: 823 DECERD--------THTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
C++ + C +C ++ SY C C G++ G C
Sbjct: 883 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLC 926
Score = 35.1 bits (77), Expect = 1.1
Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 14/73 (19%)
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDG 850
LC ++ SY C C G++ G+ C+D V+ CE + CQ C Y C C G
Sbjct: 905 LCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPG 958
Query: 851 YE-----KRGDAC 858
Y+ K DAC
Sbjct: 959 YDGQNCSKELDAC 971
>BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 193 bits (470), Expect = 3e-48
Identities = 167/563 (29%), Positives = 242/563 (42%), Gaps = 80/563 (14%)
Query: 92 CGCDHGYEHDNTSHLCRDVDEC---SWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD 148
C C GY T H +D+DEC G PC C+N PG+F C CPPGY T S
Sbjct: 418 CLCQPGYSGP-TCH--QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGS-- 470
Query: 149 ECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGT 206
CE D +EC Q C + + ++ C C PG L +C + +EC+ P +
Sbjct: 471 RCEADHNECLSQPCHPGSTCLDLLATFHCLCPPG--LEGQLCEVETNECA-SAPCLNHAD 527
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTL 265
C +L + C C GF + D++ECR C N G+C++ G+F C+C PG+
Sbjct: 528 CHDLLNGFQCICLPGFSGTRCEE--DIDECRSS--PCANGGQCQDQPGAFHCKCLPGF-- 581
Query: 266 TADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKEL 324
+G C+ +VDEC P P G SC + G + C C +G+ G+ C + C
Sbjct: 582 --EGPRCQTEVDECLSDPCPVG----ASCLDLPGAFFCLCPSGF--TGQLC-EVPLC--A 630
Query: 325 PYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRAR---PL 380
P +C + C++ C CP D + E C+ G C R+ +
Sbjct: 631 PNLCQPKQICKDQKDKANCLCP-----DGSPGCAPPEDNCTCHH----GHCQRSSCVCDV 681
Query: 381 QLARPEC------CCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP 434
PEC C S A G C P + + C G P ++++ C P
Sbjct: 682 GWTGPECEAELGGCISAPCAHGGTC----YPQPSGYNCTCPTGYTGPTCSEEMTACHSGP 737
Query: 435 DVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYE 492
C+ GG C + G + C CP + G C D C P G GTC N G +
Sbjct: 738 --CLNGGSCNPSPGGYYCTCPPSHT----GPQCQTSTDYCVSAPCFNG-GTCVNRPGTFS 790
Query: 493 CQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI- 551
C C+ GF QGP CA+ C ++ RC CP GY G C+ +
Sbjct: 791 CLCAMGF-QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYT----GGSCQTLM 845
Query: 552 DECVQEPRVCPH--ACENVVGSYICKCPEGYR--RTSAPQDSENACEDINECEEQEDLC- 606
D C Q+P CP C S+ C C +G+ + P S +++ + LC
Sbjct: 846 DLCAQKP--CPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAA-LSQGIDVSSLCH 902
Query: 607 SGGVCINTDGSFLCDCDAGFEPS 629
+GG+C+++ S+ C C GF+ S
Sbjct: 903 NGGLCVDSGPSYFCHCPPGFQGS 925
Score = 186 bits (454), Expect = 2e-46
Identities = 191/641 (29%), Positives = 255/641 (39%), Gaps = 118/641 (18%)
Query: 33 APCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKP----GTCHDTPT 88
A C P GS LC +PG Y P ++ +DEC + Q P G+C +TP
Sbjct: 405 AQCSTNPLTGS----TLCLCQPG-YSGPTCHQD--LDECLMAQQGPSPCEHGGSCLNTPG 457
Query: 89 GFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
F C C GY T C D +EC PC + C++L F C CPPG L L
Sbjct: 458 SFNCLCPPGY----TGSRCEADHNECL--SQPCHPGSTCLDLLATFHCLCPPG--LEGQL 509
Query: 148 DECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTC 207
E E +EC +H DC + + ++C C PG++ D+DEC R P G C
Sbjct: 510 CEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS-GTRCEEDIDEC-RSSPCANGGQC 566
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYT-- 264
++ PGA+ C C GF+ GP +V+EC C G C + G+F C C G+T
Sbjct: 567 QDQPGAFHCKCLPGFE-GPRCQ-TEVDECLSD--PCPVGASCLDLPGAFFCLCPSGFTGQ 622
Query: 265 ----------LTADGRNCRDVDECDELPHPCGRDG----NPSCTNTNGGYE---CSCGAG 307
L + C+D + P G G +CT +G + C C G
Sbjct: 623 LCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVG 682
Query: 308 WKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
W G C + C P CA GG C GY C CP G+ T C E C
Sbjct: 683 W--TGPECEAELGGCISAP--CAHGGTCYPQPSGYNCTCPTGY----TGPTC-SEEMTAC 733
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
+ +G C L C S G G YC CP + P
Sbjct: 734 H----SGPC-------LNGGSCNPSPG---GYYC-TCPPSHTG------------PQCQT 766
Query: 426 DLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVD--ADECALDPRICGN- 481
D C P C GG CVN G+F C C G+ G C CA P C N
Sbjct: 767 STDYCVSAP--CFNGGTCVNRPGTFSCLCAMGF----QGPRCEGKLRPSCADSP--CRNR 818
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA- 540
TC ++ G C C G+T G QT +D+ CA+ C T SF C C G+
Sbjct: 819 ATCQDSPQGPRCLCPTGYTGGSCQTLMDL--CAQKPCPRNSHCLQTGPSFHCLCLQGWTG 876
Query: 541 ----VAADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENACE 594
+ + + + +C + C + SY C CP G+ + S QD N CE
Sbjct: 877 PLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF-QGSLCQDHVNPCE 935
Query: 595 DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
C+ +G C+ +LC C G+ DG +C
Sbjct: 936 S-RPCQ------NGATCMAQPSGYLCQCAPGY----DGQNC 965
Score = 178 bits (433), Expect = 8e-44
Identities = 182/654 (27%), Positives = 268/654 (40%), Gaps = 107/654 (16%)
Query: 21 YLCCCSVGHAWGAPCEA-----CPP----RGSPAHTALCGEKPGEYINPVTNETKPI-DE 70
+LC C G G C+A CPP + H G + T E + D
Sbjct: 101 FLCTCLPGFT-GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDF 159
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNL 129
C P + G C T QC C G+E H C RDV+EC PC C N
Sbjct: 160 CSANPCV-NGGVCLATYPQIQCHCPPGFE----GHACERDVNECFQDPGPCPKGTSCHNT 214
Query: 130 PGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCR----NTIGSYRCECKPGYTL 184
G+F+C CP G P CE C + + G C+ + C C PG+ +
Sbjct: 215 LGSFQCLCPVGQE-GP---RCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGF-I 269
Query: 185 RENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCV-DVNECR-EGGM 241
+ + D C + C+NG TC++ Y C C + + DC DV+EC +G
Sbjct: 270 GPDCEVNPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGW---DCSEDVDECETQGPP 324
Query: 242 VCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGG 299
CRNG C+N+ GSF C C G+ G +C + +D+C + C +C + G
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDC--IAATCA--PGSTCIDRVGS 376
Query: 300 YECSCGAGWKLVGRRCVDRDECKELPYVCAG-GECRN--FNGGYVCECPAGWRFDKTAAV 356
+ C C G G C D C P C G +C G +C C G+ +
Sbjct: 377 FSCLCPPG--RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTLCLCQPGY----SGPT 428
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
C + E C A+ Q P C G + C P F +C
Sbjct: 429 CHQDLDE----------CLMAQ--QGPSP---CEHGGS----CLNTP----GSFNCLCPP 465
Query: 417 GMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALD 475
G D +EC +P G C++ +F C CP G +G C V+ +ECA
Sbjct: 466 GYTGSRCEADHNECLSQP-CHPGSTCLDLLATFHCLCPPGL----EGQLCEVETNECASA 520
Query: 476 PRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
P + + C + G++C C PGF+ + D+DEC + +C + G+F C C
Sbjct: 521 PCL-NHADCHDLLNGFQCICLPGFSGTRCEE--DIDECRSSPCANGGQCQDQPGAFHCKC 577
Query: 536 PYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGY--RRTSAPQDSENA 592
G+ +G C+ ++DEC+ +P +C ++ G++ C CP G+ + P + N
Sbjct: 578 LPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNL 633
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS 646
C+ C++Q+D + C+ DGS G P ED C G C RS
Sbjct: 634 CQPKQICKDQKDKAN---CLCPDGS------PGCAPPEDNCTC---HHGHCQRS 675
Score = 171 bits (415), Expect = 1e-41
Identities = 169/571 (29%), Positives = 222/571 (38%), Gaps = 101/571 (17%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P G C D P F C C G+E +VDEC PC A C+
Sbjct: 552 IDECRSSP-CANGGQCQDQPGAFHCKCLPGFEGPRCQ---TEVDECL--SDPCPVGASCL 605
Query: 128 NLPGAFECRCPPGYR--------LTPSLDECEDVDECGDQR-----ICDHGDCRNTIGSY 174
+LPGAF C CP G+ P+L C+ C DQ+ +C G
Sbjct: 606 DLPGAFFCLCPSGFTGQLCEVPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPED 663
Query: 175 RCECKPGYTLRENVCRDVD----ECSRP------RPVCRNGTCENLPGAYLCHCDDGFKA 224
C C G+ R + DV EC P GTC P Y C C G+
Sbjct: 664 NCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY-T 722
Query: 225 GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPH 283
GP C + G G C + G + C C P +T G C+ D C +
Sbjct: 723 GPT--CSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT----GPQCQTSTDYC--VSA 774
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVD--RDECKELPYVCAG-GECRNFNGGY 340
PC G +C N G + C C G++ G RC R C + P C C++ G
Sbjct: 775 PCFNGG--TCVNRPGTFSCLCAMGFQ--GPRCEGKLRPSCADSP--CRNRATCQDSPQGP 828
Query: 341 VCECPAGWR-------FDKTA-------AVCVDERKE---LCYDEWEAGRCHRARPLQLA 383
C CP G+ D A + C+ LC W C+ PL
Sbjct: 829 RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNL--PLSSC 886
Query: 384 RPECCCSEGAAWGRYCER---CPAPDSAEFMRICQGGMGRPNLTQD-LDECRVRPDVCVG 439
+ + S+G C C + F G G +L QD ++ C RP C
Sbjct: 887 Q-KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQG--SLCQDHVNPCESRP--CQN 941
Query: 440 GR-CVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGN-GTCSNTRGGYECQCS 496
G C+ + C+C GY DG +C + D C P C N GTC+ GG+ C C
Sbjct: 942 GATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQP--CHNHGTCTPKPGGFHCACP 995
Query: 497 PGFTQGPDQTCV-DVDECAEG--RASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DID 552
PGF C DVDEC + + T CH+ A +F C C G+ G C +ID
Sbjct: 996 PGFV---GLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT----GQWCEVEID 1048
Query: 553 ECVQEPRVCPHACENVVGS---YICKCPEGY 580
C +P CE GS +IC CP+G+
Sbjct: 1049 PCHSQPCFHGGTCEATAGSPLGFICHCPKGF 1079
Score = 167 bits (405), Expect = 2e-40
Identities = 186/634 (29%), Positives = 259/634 (40%), Gaps = 125/634 (19%)
Query: 66 KPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+ ++EC P C GT CH+T FQC C G E C E G P RG +
Sbjct: 193 RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPR----C----ELRAGPCPPRGCS 244
Query: 125 Q---CVNLP---GAFE-CRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRC 176
C +P F C CPPG+ + P +CE + D C + + G C++ + +Y C
Sbjct: 245 NGGTCQLMPEKDSTFHLCLCPPGF-IGP---DCEVNPDNCVSHQCQNGGTCQDGLDTYTC 300
Query: 177 ECKPGYTLRENVCRDVDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVN 234
C +T + DVDEC ++ P CRNG TC+N G++ C C G+ G + +++
Sbjct: 301 LCPETWT-GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW--GGTSCEENLD 357
Query: 235 ECREGGMVCRNGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+C C G C + VGSF C C PG T G C D C L PC D S
Sbjct: 358 DCIAA--TCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMC--LSQPCHGDAQCST 409
Query: 294 TNTNGGYECSCGAGWKLVGRRC-VDRDEC---KELPYVCA-GGECRNFNGGYVCECPAGW 348
G C C G+ G C D DEC ++ P C GG C N G + C CP G+
Sbjct: 410 NPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 467
Query: 349 RFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSA 408
T + C + E C + CH P C + A
Sbjct: 468 ----TGSRCEADHNE-CLSQ----PCH---------PGSTCLDLLA-------------- 495
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCV 467
F +C G+ + +EC P C+ C + F+C C G+ G C
Sbjct: 496 TFHCLCPPGLEGQLCEVETNECASAP--CLNHADCHDLLNGFQCICLPGF----SGTRCE 549
Query: 468 -DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
D DEC P C NG C + G + C+C PGF +GP + +VDEC C
Sbjct: 550 EDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF-EGP-RCQTEVDECLSDPCPVGASCL 605
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRT 583
+ G+F C CP G+ G C ++ C P +C C++ C CP+G
Sbjct: 606 DLPGAFFCLCPSGFT----GQLC-EVPLCA--PNLCQPKQICKDQKDKANCLCPDGSPGC 658
Query: 584 SAPQDS---------ENACE-DIN----ECEEQEDLC------SGGVCINTDGSFLCDCD 623
+ P+D+ ++C D+ ECE + C GG C + C C
Sbjct: 659 APPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 718
Query: 624 AGFEP---SEDGTDCIDRRTGTCYRSLVSGRCEP 654
G+ SE+ T C +G C L G C P
Sbjct: 719 TGYTGPTCSEEMTAC---HSGPC---LNGGSCNP 746
Score = 145 bits (351), Expect = 7e-34
Identities = 153/527 (29%), Positives = 211/527 (40%), Gaps = 105/527 (19%)
Query: 165 GDCRN-TIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCE-------NLPGA-- 213
G C + ++G C+C PG+ L E C+ D C + +C+NG +C+ LP +
Sbjct: 39 GTCLSLSLGQGTCQCAPGF-LGET-CQFPDPCQNAQ-LCQNGGSCQALLPAPLGLPSSPS 95
Query: 214 -----YLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCR-NTVGSFRCECAPGYTLTA 267
+LC C GF G + C + GRC G +C C PG+T
Sbjct: 96 PLTPSFLCTCLPGF-TGERCQAKLEDPCPPS-FCSKRGRCHIQASGRPQCSCMPGWT--- 150
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV-DRDECKELPY 326
G C+ D C +PC G C T +C C G++ G C D +EC + P
Sbjct: 151 -GEQCQLRDFCSA--NPCVNGG--VCLATYPQIQCHCPPGFE--GHACERDVNECFQDPG 203
Query: 327 VCAGG-ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARP 385
C G C N G + C CP G + C E AG C P
Sbjct: 204 PCPKGTSCHNTLGSFQCLCPVG------------QEGPRC--ELRAGPC----------P 239
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN- 444
CS G C+ P DS + +C G P +C V PD CV +C N
Sbjct: 240 PRGCSNGGT----CQLMPEKDSTFHLCLCPPGFIGP-------DCEVNPDNCVSHQCQNG 288
Query: 445 ---TDG--SFRCECPDGYVLAPDGLSCV-DADECALD-PRICGNG-TCSNTRGGYECQCS 496
DG ++ C CP+ + G C D DEC P C NG TC N+ G + C C
Sbjct: 289 GTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
Query: 497 PGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
G+ G ++D+C + C + GSF C CP G G+ C D C+
Sbjct: 345 SGW--GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMCLS 398
Query: 557 EPRVCPHACEN--VVGSYICKCPEGYRRTSAPQDSEN---ACEDINECEEQEDLCSGGVC 611
+P C + GS +C C GY + QD + A + + CE GG C
Sbjct: 399 QPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH------GGSC 452
Query: 612 INTDGSFLCDCDAGFEPSE---DGTDCIDRRT---GTCYRSLVSGRC 652
+NT GSF C C G+ S D +C+ + TC L + C
Sbjct: 453 LNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 499
Score = 121 bits (292), Expect = 1e-26
Identities = 102/340 (30%), Positives = 139/340 (40%), Gaps = 44/340 (12%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGY 141
TC D+P G +C C GY + L +D C+ + PC + C+ +F C C G+
Sbjct: 820 TCQDSPQGPRCLCPTGYTGGSCQTL---MDLCA--QKPCPRNSHCLQTGPSFHCLCLQGW 874
Query: 142 R---LTPSLDECEDV---DECGDQRICDHGD-CRNTIGSYRCECKPGYTLRENVCRD-VD 193
L C+ +C +G C ++ SY C C PG+ + ++C+D V+
Sbjct: 875 TGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF--QGSLCQDHVN 932
Query: 194 EC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRN 250
C SRP C+NG TC P YLC C G+ N +++ C+ C N G C
Sbjct: 933 PCESRP---CQNGATCMAQPSGYLCQCAPGYDG--QNCSKELDACQ--SQPCHNHGTCTP 985
Query: 251 TVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
G F C C PG+ G C DVDEC L PC G +C + + C C G
Sbjct: 986 KPGGFHCACPPGFV----GLRCEGDVDEC--LDQPCHPTGTAACHSLANAFYCQCLPGH- 1038
Query: 310 LVGRRC-VDRDECKELPYVCAGGECRNFNG---GYVCECPAGWRFDKTAAVCVDERKELC 365
G+ C V+ D C P GG C G G++C CP G+ C
Sbjct: 1039 -TGQWCEVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCPKGFE----GPTCSHRAPSCG 1092
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
+ G P P C C G G C PAP
Sbjct: 1093 FHHCHHGGLCLPSPKPGFPPRCACLSGYG-GPDCLTPPAP 1131
Score = 105 bits (251), Expect = 9e-22
Identities = 83/256 (32%), Positives = 114/256 (44%), Gaps = 44/256 (17%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
++ C+ P C+ G TC P+G+ C C GY+ N S +++D C PC C
Sbjct: 931 VNPCESRP--CQNGATCMAQPSGYLCQCAPGYDGQNCS---KELDACQ--SQPCHNHGTC 983
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGD--CRNTIGSYRCECKPGYT 183
PG F C CPPG+ L CE DVDEC DQ G C + ++ C+C PG+T
Sbjct: 984 TPKPGGFHCACPPGF---VGL-RCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT 1039
Query: 184 LRENVCR-DVDECSRPRPVCRNGTCENLPGA---YLCHCDDGFKAGP----NNDCVDVNE 235
C ++D C +P GTCE G+ ++CHC GF+ GP +
Sbjct: 1040 --GQWCEVEIDPC-HSQPCFHGGTCEATAGSPLGFICHCPKGFE-GPTCSHRAPSCGFHH 1095
Query: 236 CREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE---CDELPHPCGRDGNPS 292
C GG+ + + RC C GY G +C C P PC +G S
Sbjct: 1096 CHHGGLCLPSPKPGFPP---RCACLSGY----GGPDCLTPPAPKGCGP-PSPCLYNG--S 1145
Query: 293 CTNTNG----GYECSC 304
C+ T G G+ CSC
Sbjct: 1146 CSETTGLGGPGFRCSC 1161
Score = 96.7 bits (230), Expect = 3e-19
Identities = 119/412 (28%), Positives = 163/412 (39%), Gaps = 91/412 (22%)
Query: 243 CRNG-RCRN-TVGSFRCECAPGYTLTADGRNCRDVDECDE-------------LPHPCGR 287
C NG C + ++G C+CAPG+ G C+ D C LP P G
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFL----GETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 90
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECR-NFNGGYVCECP 345
+PS + + C+C G+ G RC + E P C+ G C +G C C
Sbjct: 91 PSSPSPLTPS--FLCTCLPGF--TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCE-RCPA 404
GW T C + ++ C A P C + G Y + +C
Sbjct: 147 PGW----TGEQC--QLRDFC----------SANP--------CVNGGVCLATYPQIQCHC 182
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDG 463
P E C+ +D++EC P C G C NT GSF+C CP G +G
Sbjct: 183 PPGFE-GHACE---------RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEG 228
Query: 464 LSC-VDADECALDPRICGN-GTC----SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGR 517
C + A C PR C N GTC + C C PGF GPD V+ D C +
Sbjct: 229 PRCELRAGPC--PPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI-GPDCE-VNPDNCVSHQ 284
Query: 518 ASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDEC-VQEPRVCPH--ACENVVGSYI 573
C + ++ C CP + G C D+DEC Q P C + C+N GS+
Sbjct: 285 CQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
C C G+ TS E++++C G CI+ GSF C C G
Sbjct: 341 CVCVSGWGGTSCE-------ENLDDC-IAATCAPGSTCIDRVGSFSCLCPPG 384
Score = 94.3 bits (224), Expect = 2e-18
Identities = 130/513 (25%), Positives = 177/513 (34%), Gaps = 80/513 (15%)
Query: 380 LQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG 439
L L + C C+ G E C PD + ++CQ G L P
Sbjct: 44 LSLGQGTCQCAPGFLG----ETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 99
Query: 440 GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGN-GTCS-NTRGGYECQCSP 497
SF C C G+ G C E P C G C G +C C P
Sbjct: 100 --------SFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMP 147
Query: 498 GFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQ 556
G+T + C D C+ C T +C CP G+ +G C RD++EC Q
Sbjct: 148 GWT---GEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQ 200
Query: 557 EPRVCPH--ACENVVGSYICKCP---EGYR-RTSAPQDSENACEDINECEEQEDLCSG-G 609
+P CP +C N +GS+ C CP EG R A C + C+ + S
Sbjct: 201 DPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFH 260
Query: 610 VCINTDGSFLCDCDAGFE-----PSEDGTDC---IDRRTGTCYRSLVSGRCEPEXXXXXX 661
+C+ G DC+ + ++G C +D T C + C +
Sbjct: 261 LCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECET 320
Query: 662 XXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWG-SECELCPAPGSPARLDLCTAVNLTPX 720
G C C G WG + CE LD C A P
Sbjct: 321 QGPPHCRNGGTCQNSAGSF---HCVCVSG--WGGTSCE--------ENLDDCIAATCAPG 367
Query: 721 XXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP----GLCAP----GRFRCVCGPGYR 772
L D+ C + P C+ G C+C PGY
Sbjct: 368 STCIDRVGSFSCLCPPGRTGLLCHLEDM--CLSQPCHGDAQCSTNPLTGSTLCLCQPGY- 424
Query: 773 PAGEVC-ADVDECAVR---PPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR-DVDEC 825
+G C D+DEC + P PC+ C NT GS++CLC GY G+ C D +EC
Sbjct: 425 -SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNEC 479
Query: 826 ERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
C + ++ C C G E G C
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLE--GQLC 510
Score = 77.4 bits (182), Expect = 2e-13
Identities = 113/396 (28%), Positives = 139/396 (35%), Gaps = 79/396 (19%)
Query: 21 YLCCCSVGHAWGAPCE--ACPPRGSPAHT-ALCGEKPGEYINPVT------NETKPIDEC 71
Y C C G G+ C+ P P A C +P Y+ N +K +D C
Sbjct: 914 YFCHCPPGFQ-GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDAC 972
Query: 72 DIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCR--GMAQCV 127
P C GTC P GF C C G+ C DVDEC PC G A C
Sbjct: 973 QSQP--CHNHGTCTPKPGGFHCACPPGF----VGLRCEGDVDECL--DQPCHPTGTAACH 1024
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGS---YRCECKPGYTL 184
+L AF C+C PG+ T E E +D C Q G C T GS + C C G+
Sbjct: 1025 SLANAFYCQCLPGH--TGQWCEVE-IDPCHSQPCFHGGTCEATAGSPLGFICHCPKGF-- 1079
Query: 185 RENVCRDVDECSRPRPVC------RNGTCENLPGAYL---CHCDDGFKAGPNNDCVDV-- 233
+ CS P C G C P C C G+ GP DC+
Sbjct: 1080 ------EGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGY-GGP--DCLTPPA 1130
Query: 234 -NECREGGMVCRNGRCRNTVG----SFRCEC---APGYTLTADG-RNCRDVDECDELPHP 284
C NG C T G FRC C +PG G + C
Sbjct: 1131 PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAG 1190
Query: 285 CGRDGNPSCTNTNGGYECSCGAG--WKLVGR--RCVDRDECKELPYVCAGGECRNFNGGY 340
C G N +GG +CS G WK RC + C EC F+G Y
Sbjct: 1191 CSGPGG----NWDGG-DCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECL-FDG-Y 1243
Query: 341 VCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHR 376
CE P C + C+D + G C +
Sbjct: 1244 DCETPPA---------CTPAYDQYCHDHFHNGHCEK 1270
Score = 71.7 bits (168), Expect = 1e-11
Identities = 108/408 (26%), Positives = 142/408 (34%), Gaps = 80/408 (19%)
Query: 472 CALDPRICGNG-TC-SNTRGGYECQCSPGF----TQGPDQTCVDVDECAEGRASCTFRCH 525
C P C NG TC S + G CQC+PGF Q PD C + C G SC
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNG-GSCQALLP 85
Query: 526 NTAG----------SFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH--ACE-NVVGSY 572
G SF CTC G+ G C+ E P C C G
Sbjct: 86 APLGLPSSPSPLTPSFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRP 141
Query: 573 ICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDG 632
C C G+ T + C N C +GGVC+ T C C GFE G
Sbjct: 142 QCSCMPGW--TGEQCQLRDFC-SANPC------VNGGVCLATYPQIQCHCPPGFE----G 188
Query: 633 TDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAA 692
C +R C++ G C P+ +A C G +
Sbjct: 189 HAC-ERDVNECFQD--PGPC-PKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCS 244
Query: 693 WGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECA 752
G C+L P S L LC + P D + D C
Sbjct: 245 NGGTCQLMPEKDSTFHLCLCPPGFIGP-----------------------DCEVNPDNCV 281
Query: 753 AIP----GLCAPG--RFRCVCGPGYRPAGEVCADVDECAVR-PPPCDQ--LCHNTDGSYD 803
+ G C G + C+C P + DVDEC + PP C C N+ GS+
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLC-PETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340
Query: 804 CLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDG 850
C+C +G+ G +C + +D+C T C + GS+ C C G
Sbjct: 341 CVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG 384
Score = 62.5 bits (145), Expect = 6e-09
Identities = 39/111 (35%), Positives = 53/111 (47%), Gaps = 14/111 (12%)
Query: 747 DVDECAAIP----GLCA--PGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D+DEC + P G C PG F C C PG+ G C +VDEC P P C +
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFE--GPRCQTEVDECLSDPCPVGASCLDLP 608
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
G++ CLC +G+ G C +V C + +QIC + + C C DG
Sbjct: 609 GAFFCLCPSGF----TGQLC-EVPLCAPNLCQPKQICKDQKDKANCLCPDG 654
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 18/117 (15%)
Query: 746 ADVDECAAIPGLCAPGR--------FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCH 796
AD +EC + P C PG F C+C PG G++C + +ECA P CH
Sbjct: 474 ADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE--GQLCEVETNECASAPCLNHADCH 529
Query: 797 NTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+ + C+C G+ G C D+DEC C + G++ C C G+E
Sbjct: 530 DLLNGFQCICLPGFS----GTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE 582
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/113 (31%), Positives = 54/113 (47%), Gaps = 14/113 (12%)
Query: 747 DVDECAAIPGL----CAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+ +ECA+ P L C F+C+C PG+ +G C D+DEC P C +
Sbjct: 513 ETNECASAPCLNHADCHDLLNGFQCICLPGF--SGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G++ C C G+E G C+ +VDEC D C + G++ C C G+
Sbjct: 571 GAFHCKCLPGFE----GPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGF 619
Score = 54.4 bits (125), Expect = 2e-06
Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 10/109 (9%)
Query: 747 DVDECAAIPGLCAPG--RFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYD 803
DV GLC + C C PG++ G +C D V+ C RP C Y
Sbjct: 896 DVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHVNPCESRPCQNGATCMAQPSGYL 953
Query: 804 CLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C C GY DG NC +++D C+ C+ G + C+C G+
Sbjct: 954 CQCAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGF 998
Score = 48.4 bits (110), Expect = 1e-04
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 8/97 (8%)
Query: 757 LCAPGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 815
L PG F C+C PGY G C AD +EC +P C + ++ CLC G E
Sbjct: 453 LNTPGSFNCLCPPGY--TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE---- 506
Query: 816 GANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C + +EC C + ++C C G+
Sbjct: 507 GQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 543
Score = 42.3 bits (95), Expect = 0.007
Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 10/101 (9%)
Query: 749 DECAAIPGLCAPGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCR 807
D C G C R CVC G+ G C A++ C P C+ Y+C C
Sbjct: 663 DNCTCHHGHCQ--RSSCVCDVGW--TGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 718
Query: 808 TGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSC 847
TGY G C ++ C C+ + G Y C+C
Sbjct: 719 TGY----TGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 755
Score = 40.3 bits (90), Expect = 0.028
Identities = 26/101 (25%), Positives = 37/101 (36%), Gaps = 7/101 (6%)
Query: 759 APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
+PG + C C P + G C D C P C N G++ CLC G++
Sbjct: 747 SPGGYYCTCPPSH--TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEG 804
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
R C + C ++ C C GY G +C
Sbjct: 805 KLR--PSCADSPCRNRATCQDSPQGPRCLCPTGY--TGGSC 841
Score = 39.9 bits (89), Expect = 0.038
Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 18/106 (16%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DV 822
RC+C GY G +D CA +P P + C T S+ CLC G+ G C +
Sbjct: 829 RCLCPTGYT-GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGW----TGPLCNLPL 883
Query: 823 DECERD--------THTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
C++ + C +C ++ SY C C G++ G C
Sbjct: 884 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLC 927
Score = 35.1 bits (77), Expect = 1.1
Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 14/73 (19%)
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDG 850
LC ++ SY C C G++ G+ C+D V+ CE + CQ C Y C C G
Sbjct: 906 LCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPG 959
Query: 851 YE-----KRGDAC 858
Y+ K DAC
Sbjct: 960 YDGQNCSKELDAC 972
>BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 193 bits (470), Expect = 3e-48
Identities = 167/563 (29%), Positives = 242/563 (42%), Gaps = 80/563 (14%)
Query: 92 CGCDHGYEHDNTSHLCRDVDEC---SWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD 148
C C GY T H +D+DEC G PC C+N PG+F C CPPGY T S
Sbjct: 418 CLCQPGYSGP-TCH--QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGS-- 470
Query: 149 ECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGT 206
CE D +EC Q C + + ++ C C PG L +C + +EC+ P +
Sbjct: 471 RCEADHNECLSQPCHPGSTCLDLLATFHCLCPPG--LEGQLCEVETNECA-SAPCLNHAD 527
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTL 265
C +L + C C GF + D++ECR C N G+C++ G+F C+C PG+
Sbjct: 528 CHDLLNGFQCICLPGFSGTRCEE--DIDECRSS--PCANGGQCQDQPGAFHCKCLPGF-- 581
Query: 266 TADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKEL 324
+G C+ +VDEC P P G SC + G + C C +G+ G+ C + C
Sbjct: 582 --EGPRCQTEVDECLSDPCPVG----ASCLDLPGAFFCLCPSGF--TGQLC-EVPLC--A 630
Query: 325 PYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRAR---PL 380
P +C + C++ C CP D + E C+ G C R+ +
Sbjct: 631 PNLCQPKQICKDQKDKANCLCP-----DGSPGCAPPEDNCTCHH----GHCQRSSCVCDV 681
Query: 381 QLARPEC------CCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP 434
PEC C S A G C P + + C G P ++++ C P
Sbjct: 682 GWTGPECEAELGGCISAPCAHGGTC----YPQPSGYNCTCPTGYTGPTCSEEMTACHSGP 737
Query: 435 DVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYE 492
C+ GG C + G + C CP + G C D C P G GTC N G +
Sbjct: 738 --CLNGGSCNPSPGGYYCTCPPSHT----GPQCQTSTDYCVSAPCFNG-GTCVNRPGTFS 790
Query: 493 CQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI- 551
C C+ GF QGP CA+ C ++ RC CP GY G C+ +
Sbjct: 791 CLCAMGF-QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYT----GGSCQTLM 845
Query: 552 DECVQEPRVCPH--ACENVVGSYICKCPEGYR--RTSAPQDSENACEDINECEEQEDLC- 606
D C Q+P CP C S+ C C +G+ + P S +++ + LC
Sbjct: 846 DLCAQKP--CPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAA-LSQGIDVSSLCH 902
Query: 607 SGGVCINTDGSFLCDCDAGFEPS 629
+GG+C+++ S+ C C GF+ S
Sbjct: 903 NGGLCVDSGPSYFCHCPPGFQGS 925
Score = 186 bits (454), Expect = 2e-46
Identities = 191/641 (29%), Positives = 255/641 (39%), Gaps = 118/641 (18%)
Query: 33 APCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKP----GTCHDTPT 88
A C P GS LC +PG Y P ++ +DEC + Q P G+C +TP
Sbjct: 405 AQCSTNPLTGS----TLCLCQPG-YSGPTCHQD--LDECLMAQQGPSPCEHGGSCLNTPG 457
Query: 89 GFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
F C C GY T C D +EC PC + C++L F C CPPG L L
Sbjct: 458 SFNCLCPPGY----TGSRCEADHNECL--SQPCHPGSTCLDLLATFHCLCPPG--LEGQL 509
Query: 148 DECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTC 207
E E +EC +H DC + + ++C C PG++ D+DEC R P G C
Sbjct: 510 CEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS-GTRCEEDIDEC-RSSPCANGGQC 566
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYT-- 264
++ PGA+ C C GF+ GP +V+EC C G C + G+F C C G+T
Sbjct: 567 QDQPGAFHCKCLPGFE-GPRCQ-TEVDECLSD--PCPVGASCLDLPGAFFCLCPSGFTGQ 622
Query: 265 ----------LTADGRNCRDVDECDELPHPCGRDG----NPSCTNTNGGYE---CSCGAG 307
L + C+D + P G G +CT +G + C C G
Sbjct: 623 LCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVG 682
Query: 308 WKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
W G C + C P CA GG C GY C CP G+ T C E C
Sbjct: 683 W--TGPECEAELGGCISAP--CAHGGTCYPQPSGYNCTCPTGY----TGPTC-SEEMTAC 733
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
+ +G C L C S G G YC CP + P
Sbjct: 734 H----SGPC-------LNGGSCNPSPG---GYYC-TCPPSHTG------------PQCQT 766
Query: 426 DLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVD--ADECALDPRICGN- 481
D C P C GG CVN G+F C C G+ G C CA P C N
Sbjct: 767 STDYCVSAP--CFNGGTCVNRPGTFSCLCAMGF----QGPRCEGKLRPSCADSP--CRNR 818
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA- 540
TC ++ G C C G+T G QT +D+ CA+ C T SF C C G+
Sbjct: 819 ATCQDSPQGPRCLCPTGYTGGSCQTLMDL--CAQKPCPRNSHCLQTGPSFHCLCLQGWTG 876
Query: 541 ----VAADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENACE 594
+ + + + +C + C + SY C CP G+ + S QD N CE
Sbjct: 877 PLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF-QGSLCQDHVNPCE 935
Query: 595 DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
C+ +G C+ +LC C G+ DG +C
Sbjct: 936 S-RPCQ------NGATCMAQPSGYLCQCAPGY----DGQNC 965
Score = 178 bits (433), Expect = 8e-44
Identities = 182/654 (27%), Positives = 268/654 (40%), Gaps = 107/654 (16%)
Query: 21 YLCCCSVGHAWGAPCEA-----CPP----RGSPAHTALCGEKPGEYINPVTNETKPI-DE 70
+LC C G G C+A CPP + H G + T E + D
Sbjct: 101 FLCTCLPGFT-GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDF 159
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNL 129
C P + G C T QC C G+E H C RDV+EC PC C N
Sbjct: 160 CSANPCV-NGGVCLATYPQIQCHCPPGFE----GHACERDVNECFQDPGPCPKGTSCHNT 214
Query: 130 PGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCR----NTIGSYRCECKPGYTL 184
G+F+C CP G P CE C + + G C+ + C C PG+ +
Sbjct: 215 LGSFQCLCPVGQE-GP---RCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGF-I 269
Query: 185 RENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCV-DVNECR-EGGM 241
+ + D C + C+NG TC++ Y C C + + DC DV+EC +G
Sbjct: 270 GPDCEVNPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGW---DCSEDVDECETQGPP 324
Query: 242 VCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGG 299
CRNG C+N+ GSF C C G+ G +C + +D+C + C +C + G
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDC--IAATCA--PGSTCIDRVGS 376
Query: 300 YECSCGAGWKLVGRRCVDRDECKELPYVCAG-GECRN--FNGGYVCECPAGWRFDKTAAV 356
+ C C G G C D C P C G +C G +C C G+ +
Sbjct: 377 FSCLCPPG--RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTLCLCQPGY----SGPT 428
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
C + E C A+ Q P C G + C P F +C
Sbjct: 429 CHQDLDE----------CLMAQ--QGPSP---CEHGGS----CLNTP----GSFNCLCPP 465
Query: 417 GMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALD 475
G D +EC +P G C++ +F C CP G +G C V+ +ECA
Sbjct: 466 GYTGSRCEADHNECLSQP-CHPGSTCLDLLATFHCLCPPGL----EGQLCEVETNECASA 520
Query: 476 PRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
P + + C + G++C C PGF+ + D+DEC + +C + G+F C C
Sbjct: 521 PCL-NHADCHDLLNGFQCICLPGFSGTRCEE--DIDECRSSPCANGGQCQDQPGAFHCKC 577
Query: 536 PYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGY--RRTSAPQDSENA 592
G+ +G C+ ++DEC+ +P +C ++ G++ C CP G+ + P + N
Sbjct: 578 LPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNL 633
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS 646
C+ C++Q+D + C+ DGS G P ED C G C RS
Sbjct: 634 CQPKQICKDQKDKAN---CLCPDGS------PGCAPPEDNCTC---HHGHCQRS 675
Score = 171 bits (415), Expect = 1e-41
Identities = 169/571 (29%), Positives = 222/571 (38%), Gaps = 101/571 (17%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P G C D P F C C G+E +VDEC PC A C+
Sbjct: 552 IDECRSSP-CANGGQCQDQPGAFHCKCLPGFEGPRCQ---TEVDECL--SDPCPVGASCL 605
Query: 128 NLPGAFECRCPPGYR--------LTPSLDECEDVDECGDQR-----ICDHGDCRNTIGSY 174
+LPGAF C CP G+ P+L C+ C DQ+ +C G
Sbjct: 606 DLPGAFFCLCPSGFTGQLCEVPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPED 663
Query: 175 RCECKPGYTLRENVCRDVD----ECSRP------RPVCRNGTCENLPGAYLCHCDDGFKA 224
C C G+ R + DV EC P GTC P Y C C G+
Sbjct: 664 NCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY-T 722
Query: 225 GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPH 283
GP C + G G C + G + C C P +T G C+ D C +
Sbjct: 723 GPT--CSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT----GPQCQTSTDYC--VSA 774
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVD--RDECKELPYVCAG-GECRNFNGGY 340
PC G +C N G + C C G++ G RC R C + P C C++ G
Sbjct: 775 PCFNGG--TCVNRPGTFSCLCAMGFQ--GPRCEGKLRPSCADSP--CRNRATCQDSPQGP 828
Query: 341 VCECPAGWR-------FDKTA-------AVCVDERKE---LCYDEWEAGRCHRARPLQLA 383
C CP G+ D A + C+ LC W C+ PL
Sbjct: 829 RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNL--PLSSC 886
Query: 384 RPECCCSEGAAWGRYCER---CPAPDSAEFMRICQGGMGRPNLTQD-LDECRVRPDVCVG 439
+ + S+G C C + F G G +L QD ++ C RP C
Sbjct: 887 Q-KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQG--SLCQDHVNPCESRP--CQN 941
Query: 440 GR-CVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGN-GTCSNTRGGYECQCS 496
G C+ + C+C GY DG +C + D C P C N GTC+ GG+ C C
Sbjct: 942 GATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQP--CHNHGTCTPKPGGFHCACP 995
Query: 497 PGFTQGPDQTCV-DVDECAEG--RASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DID 552
PGF C DVDEC + + T CH+ A +F C C G+ G C +ID
Sbjct: 996 PGFV---GLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT----GQWCEVEID 1048
Query: 553 ECVQEPRVCPHACENVVGS---YICKCPEGY 580
C +P CE GS +IC CP+G+
Sbjct: 1049 PCHSQPCFHGGTCEATAGSPLGFICHCPKGF 1079
Score = 167 bits (405), Expect = 2e-40
Identities = 186/634 (29%), Positives = 259/634 (40%), Gaps = 125/634 (19%)
Query: 66 KPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+ ++EC P C GT CH+T FQC C G E C E G P RG +
Sbjct: 193 RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPR----C----ELRAGPCPPRGCS 244
Query: 125 Q---CVNLP---GAFE-CRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRC 176
C +P F C CPPG+ + P +CE + D C + + G C++ + +Y C
Sbjct: 245 NGGTCQLMPEKDSTFHLCLCPPGF-IGP---DCEVNPDNCVSHQCQNGGTCQDGLDTYTC 300
Query: 177 ECKPGYTLRENVCRDVDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVN 234
C +T + DVDEC ++ P CRNG TC+N G++ C C G+ G + +++
Sbjct: 301 LCPETWT-GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW--GGTSCEENLD 357
Query: 235 ECREGGMVCRNGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+C C G C + VGSF C C PG T G C D C L PC D S
Sbjct: 358 DCIAA--TCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMC--LSQPCHGDAQCST 409
Query: 294 TNTNGGYECSCGAGWKLVGRRC-VDRDEC---KELPYVCA-GGECRNFNGGYVCECPAGW 348
G C C G+ G C D DEC ++ P C GG C N G + C CP G+
Sbjct: 410 NPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 467
Query: 349 RFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSA 408
T + C + E C + CH P C + A
Sbjct: 468 ----TGSRCEADHNE-CLSQ----PCH---------PGSTCLDLLA-------------- 495
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCV 467
F +C G+ + +EC P C+ C + F+C C G+ G C
Sbjct: 496 TFHCLCPPGLEGQLCEVETNECASAP--CLNHADCHDLLNGFQCICLPGF----SGTRCE 549
Query: 468 -DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
D DEC P C NG C + G + C+C PGF +GP + +VDEC C
Sbjct: 550 EDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF-EGP-RCQTEVDECLSDPCPVGASCL 605
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRT 583
+ G+F C CP G+ G C ++ C P +C C++ C CP+G
Sbjct: 606 DLPGAFFCLCPSGFT----GQLC-EVPLCA--PNLCQPKQICKDQKDKANCLCPDGSPGC 658
Query: 584 SAPQDS---------ENACE-DIN----ECEEQEDLC------SGGVCINTDGSFLCDCD 623
+ P+D+ ++C D+ ECE + C GG C + C C
Sbjct: 659 APPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 718
Query: 624 AGFEP---SEDGTDCIDRRTGTCYRSLVSGRCEP 654
G+ SE+ T C +G C L G C P
Sbjct: 719 TGYTGPTCSEEMTAC---HSGPC---LNGGSCNP 746
Score = 145 bits (351), Expect = 7e-34
Identities = 153/527 (29%), Positives = 211/527 (40%), Gaps = 105/527 (19%)
Query: 165 GDCRN-TIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCE-------NLPGA-- 213
G C + ++G C+C PG+ L E C+ D C + +C+NG +C+ LP +
Sbjct: 39 GTCLSLSLGQGTCQCAPGF-LGET-CQFPDPCQNAQ-LCQNGGSCQALLPAPLGLPSSPS 95
Query: 214 -----YLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCR-NTVGSFRCECAPGYTLTA 267
+LC C GF G + C + GRC G +C C PG+T
Sbjct: 96 PLTPSFLCTCLPGF-TGERCQAKLEDPCPPS-FCSKRGRCHIQASGRPQCSCMPGWT--- 150
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV-DRDECKELPY 326
G C+ D C +PC G C T +C C G++ G C D +EC + P
Sbjct: 151 -GEQCQLRDFCSA--NPCVNGG--VCLATYPQIQCHCPPGFE--GHACERDVNECFQDPG 203
Query: 327 VCAGG-ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARP 385
C G C N G + C CP G + C E AG C P
Sbjct: 204 PCPKGTSCHNTLGSFQCLCPVG------------QEGPRC--ELRAGPC----------P 239
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN- 444
CS G C+ P DS + +C G P +C V PD CV +C N
Sbjct: 240 PRGCSNGGT----CQLMPEKDSTFHLCLCPPGFIGP-------DCEVNPDNCVSHQCQNG 288
Query: 445 ---TDG--SFRCECPDGYVLAPDGLSCV-DADECALD-PRICGNG-TCSNTRGGYECQCS 496
DG ++ C CP+ + G C D DEC P C NG TC N+ G + C C
Sbjct: 289 GTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
Query: 497 PGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
G+ G ++D+C + C + GSF C CP G G+ C D C+
Sbjct: 345 SGW--GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMCLS 398
Query: 557 EPRVCPHACEN--VVGSYICKCPEGYRRTSAPQDSEN---ACEDINECEEQEDLCSGGVC 611
+P C + GS +C C GY + QD + A + + CE GG C
Sbjct: 399 QPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH------GGSC 452
Query: 612 INTDGSFLCDCDAGFEPSE---DGTDCIDRRT---GTCYRSLVSGRC 652
+NT GSF C C G+ S D +C+ + TC L + C
Sbjct: 453 LNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 499
Score = 121 bits (292), Expect = 1e-26
Identities = 102/340 (30%), Positives = 139/340 (40%), Gaps = 44/340 (12%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGY 141
TC D+P G +C C GY + L +D C+ + PC + C+ +F C C G+
Sbjct: 820 TCQDSPQGPRCLCPTGYTGGSCQTL---MDLCA--QKPCPRNSHCLQTGPSFHCLCLQGW 874
Query: 142 R---LTPSLDECEDV---DECGDQRICDHGD-CRNTIGSYRCECKPGYTLRENVCRD-VD 193
L C+ +C +G C ++ SY C C PG+ + ++C+D V+
Sbjct: 875 TGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF--QGSLCQDHVN 932
Query: 194 EC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRN 250
C SRP C+NG TC P YLC C G+ N +++ C+ C N G C
Sbjct: 933 PCESRP---CQNGATCMAQPSGYLCQCAPGYDG--QNCSKELDACQ--SQPCHNHGTCTP 985
Query: 251 TVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
G F C C PG+ G C DVDEC L PC G +C + + C C G
Sbjct: 986 KPGGFHCACPPGFV----GLRCEGDVDEC--LDQPCHPTGTAACHSLANAFYCQCLPGH- 1038
Query: 310 LVGRRC-VDRDECKELPYVCAGGECRNFNG---GYVCECPAGWRFDKTAAVCVDERKELC 365
G+ C V+ D C P GG C G G++C CP G+ C
Sbjct: 1039 -TGQWCEVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCPKGFE----GPTCSHRAPSCG 1092
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
+ G P P C C G G C PAP
Sbjct: 1093 FHHCHHGGLCLPSPKPGFPPRCACLSGYG-GPDCLTPPAP 1131
Score = 105 bits (251), Expect = 9e-22
Identities = 83/256 (32%), Positives = 114/256 (44%), Gaps = 44/256 (17%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
++ C+ P C+ G TC P+G+ C C GY+ N S +++D C PC C
Sbjct: 931 VNPCESRP--CQNGATCMAQPSGYLCQCAPGYDGQNCS---KELDACQ--SQPCHNHGTC 983
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGD--CRNTIGSYRCECKPGYT 183
PG F C CPPG+ L CE DVDEC DQ G C + ++ C+C PG+T
Sbjct: 984 TPKPGGFHCACPPGF---VGL-RCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT 1039
Query: 184 LRENVCR-DVDECSRPRPVCRNGTCENLPGA---YLCHCDDGFKAGP----NNDCVDVNE 235
C ++D C +P GTCE G+ ++CHC GF+ GP +
Sbjct: 1040 --GQWCEVEIDPC-HSQPCFHGGTCEATAGSPLGFICHCPKGFE-GPTCSHRAPSCGFHH 1095
Query: 236 CREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE---CDELPHPCGRDGNPS 292
C GG+ + + RC C GY G +C C P PC +G S
Sbjct: 1096 CHHGGLCLPSPKPGFPP---RCACLSGY----GGPDCLTPPAPKGCGP-PSPCLYNG--S 1145
Query: 293 CTNTNG----GYECSC 304
C+ T G G+ CSC
Sbjct: 1146 CSETTGLGGPGFRCSC 1161
Score = 96.7 bits (230), Expect = 3e-19
Identities = 119/412 (28%), Positives = 163/412 (39%), Gaps = 91/412 (22%)
Query: 243 CRNG-RCRN-TVGSFRCECAPGYTLTADGRNCRDVDECDE-------------LPHPCGR 287
C NG C + ++G C+CAPG+ G C+ D C LP P G
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFL----GETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 90
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECR-NFNGGYVCECP 345
+PS + + C+C G+ G RC + E P C+ G C +G C C
Sbjct: 91 PSSPSPLTPS--FLCTCLPGF--TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCE-RCPA 404
GW T C + ++ C A P C + G Y + +C
Sbjct: 147 PGW----TGEQC--QLRDFC----------SANP--------CVNGGVCLATYPQIQCHC 182
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDG 463
P E C+ +D++EC P C G C NT GSF+C CP G +G
Sbjct: 183 PPGFE-GHACE---------RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEG 228
Query: 464 LSC-VDADECALDPRICGN-GTC----SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGR 517
C + A C PR C N GTC + C C PGF GPD V+ D C +
Sbjct: 229 PRCELRAGPC--PPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI-GPDCE-VNPDNCVSHQ 284
Query: 518 ASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDEC-VQEPRVCPH--ACENVVGSYI 573
C + ++ C CP + G C D+DEC Q P C + C+N GS+
Sbjct: 285 CQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
C C G+ TS E++++C G CI+ GSF C C G
Sbjct: 341 CVCVSGWGGTSCE-------ENLDDC-IAATCAPGSTCIDRVGSFSCLCPPG 384
Score = 94.3 bits (224), Expect = 2e-18
Identities = 130/513 (25%), Positives = 177/513 (34%), Gaps = 80/513 (15%)
Query: 380 LQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG 439
L L + C C+ G E C PD + ++CQ G L P
Sbjct: 44 LSLGQGTCQCAPGFLG----ETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 99
Query: 440 GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGN-GTCS-NTRGGYECQCSP 497
SF C C G+ G C E P C G C G +C C P
Sbjct: 100 --------SFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMP 147
Query: 498 GFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQ 556
G+T + C D C+ C T +C CP G+ +G C RD++EC Q
Sbjct: 148 GWT---GEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQ 200
Query: 557 EPRVCPH--ACENVVGSYICKCP---EGYR-RTSAPQDSENACEDINECEEQEDLCSG-G 609
+P CP +C N +GS+ C CP EG R A C + C+ + S
Sbjct: 201 DPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFH 260
Query: 610 VCINTDGSFLCDCDAGFE-----PSEDGTDC---IDRRTGTCYRSLVSGRCEPEXXXXXX 661
+C+ G DC+ + ++G C +D T C + C +
Sbjct: 261 LCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECET 320
Query: 662 XXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWG-SECELCPAPGSPARLDLCTAVNLTPX 720
G C C G WG + CE LD C A P
Sbjct: 321 QGPPHCRNGGTCQNSAGSF---HCVCVSG--WGGTSCE--------ENLDDCIAATCAPG 367
Query: 721 XXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP----GLCAP----GRFRCVCGPGYR 772
L D+ C + P C+ G C+C PGY
Sbjct: 368 STCIDRVGSFSCLCPPGRTGLLCHLEDM--CLSQPCHGDAQCSTNPLTGSTLCLCQPGY- 424
Query: 773 PAGEVC-ADVDECAVR---PPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR-DVDEC 825
+G C D+DEC + P PC+ C NT GS++CLC GY G+ C D +EC
Sbjct: 425 -SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNEC 479
Query: 826 ERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
C + ++ C C G E G C
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLE--GQLC 510
Score = 77.4 bits (182), Expect = 2e-13
Identities = 113/396 (28%), Positives = 139/396 (35%), Gaps = 79/396 (19%)
Query: 21 YLCCCSVGHAWGAPCE--ACPPRGSPAHT-ALCGEKPGEYINPVT------NETKPIDEC 71
Y C C G G+ C+ P P A C +P Y+ N +K +D C
Sbjct: 914 YFCHCPPGFQ-GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDAC 972
Query: 72 DIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCR--GMAQCV 127
P C GTC P GF C C G+ C DVDEC PC G A C
Sbjct: 973 QSQP--CHNHGTCTPKPGGFHCACPPGF----VGLRCEGDVDECL--DQPCHPTGTAACH 1024
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGS---YRCECKPGYTL 184
+L AF C+C PG+ T E E +D C Q G C T GS + C C G+
Sbjct: 1025 SLANAFYCQCLPGH--TGQWCEVE-IDPCHSQPCFHGGTCEATAGSPLGFICHCPKGF-- 1079
Query: 185 RENVCRDVDECSRPRPVC------RNGTCENLPGAYL---CHCDDGFKAGPNNDCVDV-- 233
+ CS P C G C P C C G+ GP DC+
Sbjct: 1080 ------EGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGY-GGP--DCLTPPA 1130
Query: 234 -NECREGGMVCRNGRCRNTVG----SFRCEC---APGYTLTADG-RNCRDVDECDELPHP 284
C NG C T G FRC C +PG G + C
Sbjct: 1131 PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAG 1190
Query: 285 CGRDGNPSCTNTNGGYECSCGAG--WKLVGR--RCVDRDECKELPYVCAGGECRNFNGGY 340
C G N +GG +CS G WK RC + C EC F+G Y
Sbjct: 1191 CSGPGG----NWDGG-DCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECL-FDG-Y 1243
Query: 341 VCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHR 376
CE P C + C+D + G C +
Sbjct: 1244 DCETPPA---------CTPAYDQYCHDHFHNGHCEK 1270
Score = 71.7 bits (168), Expect = 1e-11
Identities = 108/408 (26%), Positives = 142/408 (34%), Gaps = 80/408 (19%)
Query: 472 CALDPRICGNG-TC-SNTRGGYECQCSPGF----TQGPDQTCVDVDECAEGRASCTFRCH 525
C P C NG TC S + G CQC+PGF Q PD C + C G SC
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNG-GSCQALLP 85
Query: 526 NTAG----------SFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH--ACE-NVVGSY 572
G SF CTC G+ G C+ E P C C G
Sbjct: 86 APLGLPSSPSPLTPSFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRP 141
Query: 573 ICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDG 632
C C G+ T + C N C +GGVC+ T C C GFE G
Sbjct: 142 QCSCMPGW--TGEQCQLRDFC-SANPC------VNGGVCLATYPQIQCHCPPGFE----G 188
Query: 633 TDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAA 692
C +R C++ G C P+ +A C G +
Sbjct: 189 HAC-ERDVNECFQD--PGPC-PKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCS 244
Query: 693 WGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECA 752
G C+L P S L LC + P D + D C
Sbjct: 245 NGGTCQLMPEKDSTFHLCLCPPGFIGP-----------------------DCEVNPDNCV 281
Query: 753 AIP----GLCAPG--RFRCVCGPGYRPAGEVCADVDECAVR-PPPCDQ--LCHNTDGSYD 803
+ G C G + C+C P + DVDEC + PP C C N+ GS+
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLC-PETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340
Query: 804 CLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDG 850
C+C +G+ G +C + +D+C T C + GS+ C C G
Sbjct: 341 CVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG 384
Score = 62.5 bits (145), Expect = 6e-09
Identities = 39/111 (35%), Positives = 53/111 (47%), Gaps = 14/111 (12%)
Query: 747 DVDECAAIP----GLCA--PGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D+DEC + P G C PG F C C PG+ G C +VDEC P P C +
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFE--GPRCQTEVDECLSDPCPVGASCLDLP 608
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
G++ CLC +G+ G C +V C + +QIC + + C C DG
Sbjct: 609 GAFFCLCPSGF----TGQLC-EVPLCAPNLCQPKQICKDQKDKANCLCPDG 654
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 18/117 (15%)
Query: 746 ADVDECAAIPGLCAPGR--------FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCH 796
AD +EC + P C PG F C+C PG G++C + +ECA P CH
Sbjct: 474 ADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE--GQLCEVETNECASAPCLNHADCH 529
Query: 797 NTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+ + C+C G+ G C D+DEC C + G++ C C G+E
Sbjct: 530 DLLNGFQCICLPGFS----GTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE 582
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/113 (31%), Positives = 54/113 (47%), Gaps = 14/113 (12%)
Query: 747 DVDECAAIPGL----CAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+ +ECA+ P L C F+C+C PG+ +G C D+DEC P C +
Sbjct: 513 ETNECASAPCLNHADCHDLLNGFQCICLPGF--SGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G++ C C G+E G C+ +VDEC D C + G++ C C G+
Sbjct: 571 GAFHCKCLPGFE----GPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGF 619
Score = 54.4 bits (125), Expect = 2e-06
Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 10/109 (9%)
Query: 747 DVDECAAIPGLCAPG--RFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYD 803
DV GLC + C C PG++ G +C D V+ C RP C Y
Sbjct: 896 DVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHVNPCESRPCQNGATCMAQPSGYL 953
Query: 804 CLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C C GY DG NC +++D C+ C+ G + C+C G+
Sbjct: 954 CQCAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGF 998
Score = 48.4 bits (110), Expect = 1e-04
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 8/97 (8%)
Query: 757 LCAPGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 815
L PG F C+C PGY G C AD +EC +P C + ++ CLC G E
Sbjct: 453 LNTPGSFNCLCPPGY--TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE---- 506
Query: 816 GANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C + +EC C + ++C C G+
Sbjct: 507 GQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 543
Score = 42.3 bits (95), Expect = 0.007
Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 10/101 (9%)
Query: 749 DECAAIPGLCAPGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCR 807
D C G C R CVC G+ G C A++ C P C+ Y+C C
Sbjct: 663 DNCTCHHGHCQ--RSSCVCDVGW--TGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 718
Query: 808 TGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSC 847
TGY G C ++ C C+ + G Y C+C
Sbjct: 719 TGY----TGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 755
Score = 40.3 bits (90), Expect = 0.028
Identities = 26/101 (25%), Positives = 37/101 (36%), Gaps = 7/101 (6%)
Query: 759 APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
+PG + C C P + G C D C P C N G++ CLC G++
Sbjct: 747 SPGGYYCTCPPSH--TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEG 804
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
R C + C ++ C C GY G +C
Sbjct: 805 KLR--PSCADSPCRNRATCQDSPQGPRCLCPTGY--TGGSC 841
Score = 39.9 bits (89), Expect = 0.038
Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 18/106 (16%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DV 822
RC+C GY G +D CA +P P + C T S+ CLC G+ G C +
Sbjct: 829 RCLCPTGYT-GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGW----TGPLCNLPL 883
Query: 823 DECERD--------THTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
C++ + C +C ++ SY C C G++ G C
Sbjct: 884 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLC 927
Score = 35.1 bits (77), Expect = 1.1
Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 14/73 (19%)
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDG 850
LC ++ SY C C G++ G+ C+D V+ CE + CQ C Y C C G
Sbjct: 906 LCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPG 959
Query: 851 YE-----KRGDAC 858
Y+ K DAC
Sbjct: 960 YDGQNCSKELDAC 972
>AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 193 bits (470), Expect = 3e-48
Identities = 167/563 (29%), Positives = 242/563 (42%), Gaps = 80/563 (14%)
Query: 92 CGCDHGYEHDNTSHLCRDVDEC---SWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD 148
C C GY T H +D+DEC G PC C+N PG+F C CPPGY T S
Sbjct: 418 CLCQPGYSGP-TCH--QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGS-- 470
Query: 149 ECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGT 206
CE D +EC Q C + + ++ C C PG L +C + +EC+ P +
Sbjct: 471 RCEADHNECLSQPCHPGSTCLDLLATFHCLCPPG--LEGQLCEVETNECA-SAPCLNHAD 527
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTL 265
C +L + C C GF + D++ECR C N G+C++ G+F C+C PG+
Sbjct: 528 CHDLLNGFQCICLPGFSGTRCEE--DIDECRSS--PCANGGQCQDQPGAFHCKCLPGF-- 581
Query: 266 TADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKEL 324
+G C+ +VDEC P P G SC + G + C C +G+ G+ C + C
Sbjct: 582 --EGPRCQTEVDECLSDPCPVG----ASCLDLPGAFFCLCPSGF--TGQLC-EVPLC--A 630
Query: 325 PYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRAR---PL 380
P +C + C++ C CP D + E C+ G C R+ +
Sbjct: 631 PNLCQPKQICKDQKDKANCLCP-----DGSPGCAPPEDNCTCHH----GHCQRSSCVCDV 681
Query: 381 QLARPEC------CCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP 434
PEC C S A G C P + + C G P ++++ C P
Sbjct: 682 GWTGPECEAELGGCISAPCAHGGTC----YPQPSGYNCTCPTGYTGPTCSEEMTACHSGP 737
Query: 435 DVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYE 492
C+ GG C + G + C CP + G C D C P G GTC N G +
Sbjct: 738 --CLNGGSCNPSPGGYYCTCPPSHT----GPQCQTSTDYCVSAPCFNG-GTCVNRPGTFS 790
Query: 493 CQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI- 551
C C+ GF QGP CA+ C ++ RC CP GY G C+ +
Sbjct: 791 CLCAMGF-QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYT----GGSCQTLM 845
Query: 552 DECVQEPRVCPH--ACENVVGSYICKCPEGYR--RTSAPQDSENACEDINECEEQEDLC- 606
D C Q+P CP C S+ C C +G+ + P S +++ + LC
Sbjct: 846 DLCAQKP--CPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAA-LSQGIDVSSLCH 902
Query: 607 SGGVCINTDGSFLCDCDAGFEPS 629
+GG+C+++ S+ C C GF+ S
Sbjct: 903 NGGLCVDSGPSYFCHCPPGFQGS 925
Score = 186 bits (454), Expect = 2e-46
Identities = 191/641 (29%), Positives = 255/641 (39%), Gaps = 118/641 (18%)
Query: 33 APCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKP----GTCHDTPT 88
A C P GS LC +PG Y P ++ +DEC + Q P G+C +TP
Sbjct: 405 AQCSTNPLTGS----TLCLCQPG-YSGPTCHQD--LDECLMAQQGPSPCEHGGSCLNTPG 457
Query: 89 GFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
F C C GY T C D +EC PC + C++L F C CPPG L L
Sbjct: 458 SFNCLCPPGY----TGSRCEADHNECL--SQPCHPGSTCLDLLATFHCLCPPG--LEGQL 509
Query: 148 DECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTC 207
E E +EC +H DC + + ++C C PG++ D+DEC R P G C
Sbjct: 510 CEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS-GTRCEEDIDEC-RSSPCANGGQC 566
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYT-- 264
++ PGA+ C C GF+ GP +V+EC C G C + G+F C C G+T
Sbjct: 567 QDQPGAFHCKCLPGFE-GPRCQ-TEVDECLSD--PCPVGASCLDLPGAFFCLCPSGFTGQ 622
Query: 265 ----------LTADGRNCRDVDECDELPHPCGRDG----NPSCTNTNGGYE---CSCGAG 307
L + C+D + P G G +CT +G + C C G
Sbjct: 623 LCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVG 682
Query: 308 WKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
W G C + C P CA GG C GY C CP G+ T C E C
Sbjct: 683 W--TGPECEAELGGCISAP--CAHGGTCYPQPSGYNCTCPTGY----TGPTC-SEEMTAC 733
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
+ +G C L C S G G YC CP + P
Sbjct: 734 H----SGPC-------LNGGSCNPSPG---GYYC-TCPPSHTG------------PQCQT 766
Query: 426 DLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVD--ADECALDPRICGN- 481
D C P C GG CVN G+F C C G+ G C CA P C N
Sbjct: 767 STDYCVSAP--CFNGGTCVNRPGTFSCLCAMGF----QGPRCEGKLRPSCADSP--CRNR 818
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA- 540
TC ++ G C C G+T G QT +D+ CA+ C T SF C C G+
Sbjct: 819 ATCQDSPQGPRCLCPTGYTGGSCQTLMDL--CAQKPCPRNSHCLQTGPSFHCLCLQGWTG 876
Query: 541 ----VAADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENACE 594
+ + + + +C + C + SY C CP G+ + S QD N CE
Sbjct: 877 PLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF-QGSLCQDHVNPCE 935
Query: 595 DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
C+ +G C+ +LC C G+ DG +C
Sbjct: 936 S-RPCQ------NGATCMAQPSGYLCQCAPGY----DGQNC 965
Score = 178 bits (433), Expect = 8e-44
Identities = 182/654 (27%), Positives = 268/654 (40%), Gaps = 107/654 (16%)
Query: 21 YLCCCSVGHAWGAPCEA-----CPP----RGSPAHTALCGEKPGEYINPVTNETKPI-DE 70
+LC C G G C+A CPP + H G + T E + D
Sbjct: 101 FLCTCLPGFT-GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDF 159
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNL 129
C P + G C T QC C G+E H C RDV+EC PC C N
Sbjct: 160 CSANPCV-NGGVCLATYPQIQCHCPPGFE----GHACERDVNECFQDPGPCPKGTSCHNT 214
Query: 130 PGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCR----NTIGSYRCECKPGYTL 184
G+F+C CP G P CE C + + G C+ + C C PG+ +
Sbjct: 215 LGSFQCLCPVGQE-GP---RCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGF-I 269
Query: 185 RENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCV-DVNECR-EGGM 241
+ + D C + C+NG TC++ Y C C + + DC DV+EC +G
Sbjct: 270 GPDCEVNPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGW---DCSEDVDECETQGPP 324
Query: 242 VCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGG 299
CRNG C+N+ GSF C C G+ G +C + +D+C + C +C + G
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDC--IAATCA--PGSTCIDRVGS 376
Query: 300 YECSCGAGWKLVGRRCVDRDECKELPYVCAG-GECRN--FNGGYVCECPAGWRFDKTAAV 356
+ C C G G C D C P C G +C G +C C G+ +
Sbjct: 377 FSCLCPPG--RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTLCLCQPGY----SGPT 428
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
C + E C A+ Q P C G + C P F +C
Sbjct: 429 CHQDLDE----------CLMAQ--QGPSP---CEHGGS----CLNTP----GSFNCLCPP 465
Query: 417 GMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALD 475
G D +EC +P G C++ +F C CP G +G C V+ +ECA
Sbjct: 466 GYTGSRCEADHNECLSQP-CHPGSTCLDLLATFHCLCPPGL----EGQLCEVETNECASA 520
Query: 476 PRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
P + + C + G++C C PGF+ + D+DEC + +C + G+F C C
Sbjct: 521 PCL-NHADCHDLLNGFQCICLPGFSGTRCEE--DIDECRSSPCANGGQCQDQPGAFHCKC 577
Query: 536 PYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGY--RRTSAPQDSENA 592
G+ +G C+ ++DEC+ +P +C ++ G++ C CP G+ + P + N
Sbjct: 578 LPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNL 633
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS 646
C+ C++Q+D + C+ DGS G P ED C G C RS
Sbjct: 634 CQPKQICKDQKDKAN---CLCPDGS------PGCAPPEDNCTC---HHGHCQRS 675
Score = 171 bits (415), Expect = 1e-41
Identities = 169/571 (29%), Positives = 222/571 (38%), Gaps = 101/571 (17%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P G C D P F C C G+E +VDEC PC A C+
Sbjct: 552 IDECRSSP-CANGGQCQDQPGAFHCKCLPGFEGPRCQ---TEVDECL--SDPCPVGASCL 605
Query: 128 NLPGAFECRCPPGYR--------LTPSLDECEDVDECGDQR-----ICDHGDCRNTIGSY 174
+LPGAF C CP G+ P+L C+ C DQ+ +C G
Sbjct: 606 DLPGAFFCLCPSGFTGQLCEVPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPED 663
Query: 175 RCECKPGYTLRENVCRDVD----ECSRP------RPVCRNGTCENLPGAYLCHCDDGFKA 224
C C G+ R + DV EC P GTC P Y C C G+
Sbjct: 664 NCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY-T 722
Query: 225 GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPH 283
GP C + G G C + G + C C P +T G C+ D C +
Sbjct: 723 GPT--CSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT----GPQCQTSTDYC--VSA 774
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVD--RDECKELPYVCAG-GECRNFNGGY 340
PC G +C N G + C C G++ G RC R C + P C C++ G
Sbjct: 775 PCFNGG--TCVNRPGTFSCLCAMGFQ--GPRCEGKLRPSCADSP--CRNRATCQDSPQGP 828
Query: 341 VCECPAGWR-------FDKTA-------AVCVDERKE---LCYDEWEAGRCHRARPLQLA 383
C CP G+ D A + C+ LC W C+ PL
Sbjct: 829 RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNL--PLSSC 886
Query: 384 RPECCCSEGAAWGRYCER---CPAPDSAEFMRICQGGMGRPNLTQD-LDECRVRPDVCVG 439
+ + S+G C C + F G G +L QD ++ C RP C
Sbjct: 887 Q-KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQG--SLCQDHVNPCESRP--CQN 941
Query: 440 GR-CVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGN-GTCSNTRGGYECQCS 496
G C+ + C+C GY DG +C + D C P C N GTC+ GG+ C C
Sbjct: 942 GATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQP--CHNHGTCTPKPGGFHCACP 995
Query: 497 PGFTQGPDQTCV-DVDECAEG--RASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DID 552
PGF C DVDEC + + T CH+ A +F C C G+ G C +ID
Sbjct: 996 PGFV---GLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT----GQWCEVEID 1048
Query: 553 ECVQEPRVCPHACENVVGS---YICKCPEGY 580
C +P CE GS +IC CP+G+
Sbjct: 1049 PCHSQPCFHGGTCEATAGSPLGFICHCPKGF 1079
Score = 167 bits (405), Expect = 2e-40
Identities = 186/634 (29%), Positives = 259/634 (40%), Gaps = 125/634 (19%)
Query: 66 KPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+ ++EC P C GT CH+T FQC C G E C E G P RG +
Sbjct: 193 RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPR----C----ELRAGPCPPRGCS 244
Query: 125 Q---CVNLP---GAFE-CRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRC 176
C +P F C CPPG+ + P +CE + D C + + G C++ + +Y C
Sbjct: 245 NGGTCQLMPEKDSTFHLCLCPPGF-IGP---DCEVNPDNCVSHQCQNGGTCQDGLDTYTC 300
Query: 177 ECKPGYTLRENVCRDVDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVN 234
C +T + DVDEC ++ P CRNG TC+N G++ C C G+ G + +++
Sbjct: 301 LCPETWT-GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW--GGTSCEENLD 357
Query: 235 ECREGGMVCRNGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+C C G C + VGSF C C PG T G C D C L PC D S
Sbjct: 358 DCIAA--TCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMC--LSQPCHGDAQCST 409
Query: 294 TNTNGGYECSCGAGWKLVGRRC-VDRDEC---KELPYVCA-GGECRNFNGGYVCECPAGW 348
G C C G+ G C D DEC ++ P C GG C N G + C CP G+
Sbjct: 410 NPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 467
Query: 349 RFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSA 408
T + C + E C + CH P C + A
Sbjct: 468 ----TGSRCEADHNE-CLSQ----PCH---------PGSTCLDLLA-------------- 495
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCV 467
F +C G+ + +EC P C+ C + F+C C G+ G C
Sbjct: 496 TFHCLCPPGLEGQLCEVETNECASAP--CLNHADCHDLLNGFQCICLPGF----SGTRCE 549
Query: 468 -DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
D DEC P C NG C + G + C+C PGF +GP + +VDEC C
Sbjct: 550 EDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF-EGP-RCQTEVDECLSDPCPVGASCL 605
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRT 583
+ G+F C CP G+ G C ++ C P +C C++ C CP+G
Sbjct: 606 DLPGAFFCLCPSGFT----GQLC-EVPLCA--PNLCQPKQICKDQKDKANCLCPDGSPGC 658
Query: 584 SAPQDS---------ENACE-DIN----ECEEQEDLC------SGGVCINTDGSFLCDCD 623
+ P+D+ ++C D+ ECE + C GG C + C C
Sbjct: 659 APPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 718
Query: 624 AGFEP---SEDGTDCIDRRTGTCYRSLVSGRCEP 654
G+ SE+ T C +G C L G C P
Sbjct: 719 TGYTGPTCSEEMTAC---HSGPC---LNGGSCNP 746
Score = 145 bits (351), Expect = 7e-34
Identities = 153/527 (29%), Positives = 211/527 (40%), Gaps = 105/527 (19%)
Query: 165 GDCRN-TIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCE-------NLPGA-- 213
G C + ++G C+C PG+ L E C+ D C + +C+NG +C+ LP +
Sbjct: 39 GTCLSLSLGQGTCQCAPGF-LGET-CQFPDPCQNAQ-LCQNGGSCQALLPAPLGLPSSPS 95
Query: 214 -----YLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCR-NTVGSFRCECAPGYTLTA 267
+LC C GF G + C + GRC G +C C PG+T
Sbjct: 96 PLTPSFLCTCLPGF-TGERCQAKLEDPCPPS-FCSKRGRCHIQASGRPQCSCMPGWT--- 150
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV-DRDECKELPY 326
G C+ D C +PC G C T +C C G++ G C D +EC + P
Sbjct: 151 -GEQCQLRDFCSA--NPCVNGG--VCLATYPQIQCHCPPGFE--GHACERDVNECFQDPG 203
Query: 327 VCAGG-ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARP 385
C G C N G + C CP G + C E AG C P
Sbjct: 204 PCPKGTSCHNTLGSFQCLCPVG------------QEGPRC--ELRAGPC----------P 239
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN- 444
CS G C+ P DS + +C G P +C V PD CV +C N
Sbjct: 240 PRGCSNGGT----CQLMPEKDSTFHLCLCPPGFIGP-------DCEVNPDNCVSHQCQNG 288
Query: 445 ---TDG--SFRCECPDGYVLAPDGLSCV-DADECALD-PRICGNG-TCSNTRGGYECQCS 496
DG ++ C CP+ + G C D DEC P C NG TC N+ G + C C
Sbjct: 289 GTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
Query: 497 PGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
G+ G ++D+C + C + GSF C CP G G+ C D C+
Sbjct: 345 SGW--GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMCLS 398
Query: 557 EPRVCPHACEN--VVGSYICKCPEGYRRTSAPQDSEN---ACEDINECEEQEDLCSGGVC 611
+P C + GS +C C GY + QD + A + + CE GG C
Sbjct: 399 QPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH------GGSC 452
Query: 612 INTDGSFLCDCDAGFEPSE---DGTDCIDRRT---GTCYRSLVSGRC 652
+NT GSF C C G+ S D +C+ + TC L + C
Sbjct: 453 LNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 499
Score = 121 bits (292), Expect = 1e-26
Identities = 102/340 (30%), Positives = 139/340 (40%), Gaps = 44/340 (12%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGY 141
TC D+P G +C C GY + L +D C+ + PC + C+ +F C C G+
Sbjct: 820 TCQDSPQGPRCLCPTGYTGGSCQTL---MDLCA--QKPCPRNSHCLQTGPSFHCLCLQGW 874
Query: 142 R---LTPSLDECEDV---DECGDQRICDHGD-CRNTIGSYRCECKPGYTLRENVCRD-VD 193
L C+ +C +G C ++ SY C C PG+ + ++C+D V+
Sbjct: 875 TGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF--QGSLCQDHVN 932
Query: 194 EC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRN 250
C SRP C+NG TC P YLC C G+ N +++ C+ C N G C
Sbjct: 933 PCESRP---CQNGATCMAQPSGYLCQCAPGYDG--QNCSKELDACQ--SQPCHNHGTCTP 985
Query: 251 TVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
G F C C PG+ G C DVDEC L PC G +C + + C C G
Sbjct: 986 KPGGFHCACPPGFV----GLRCEGDVDEC--LDQPCHPTGTAACHSLANAFYCQCLPGH- 1038
Query: 310 LVGRRC-VDRDECKELPYVCAGGECRNFNG---GYVCECPAGWRFDKTAAVCVDERKELC 365
G+ C V+ D C P GG C G G++C CP G+ C
Sbjct: 1039 -TGQWCEVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCPKGFE----GPTCSHRAPSCG 1092
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
+ G P P C C G G C PAP
Sbjct: 1093 FHHCHHGGLCLPSPKPGFPPRCACLSGYG-GPDCLTPPAP 1131
Score = 105 bits (251), Expect = 9e-22
Identities = 83/256 (32%), Positives = 114/256 (44%), Gaps = 44/256 (17%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
++ C+ P C+ G TC P+G+ C C GY+ N S +++D C PC C
Sbjct: 931 VNPCESRP--CQNGATCMAQPSGYLCQCAPGYDGQNCS---KELDACQ--SQPCHNHGTC 983
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGD--CRNTIGSYRCECKPGYT 183
PG F C CPPG+ L CE DVDEC DQ G C + ++ C+C PG+T
Sbjct: 984 TPKPGGFHCACPPGF---VGL-RCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT 1039
Query: 184 LRENVCR-DVDECSRPRPVCRNGTCENLPGA---YLCHCDDGFKAGP----NNDCVDVNE 235
C ++D C +P GTCE G+ ++CHC GF+ GP +
Sbjct: 1040 --GQWCEVEIDPC-HSQPCFHGGTCEATAGSPLGFICHCPKGFE-GPTCSHRAPSCGFHH 1095
Query: 236 CREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE---CDELPHPCGRDGNPS 292
C GG+ + + RC C GY G +C C P PC +G S
Sbjct: 1096 CHHGGLCLPSPKPGFPP---RCACLSGY----GGPDCLTPPAPKGCGP-PSPCLYNG--S 1145
Query: 293 CTNTNG----GYECSC 304
C+ T G G+ CSC
Sbjct: 1146 CSETTGLGGPGFRCSC 1161
Score = 96.7 bits (230), Expect = 3e-19
Identities = 119/412 (28%), Positives = 163/412 (39%), Gaps = 91/412 (22%)
Query: 243 CRNG-RCRN-TVGSFRCECAPGYTLTADGRNCRDVDECDE-------------LPHPCGR 287
C NG C + ++G C+CAPG+ G C+ D C LP P G
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFL----GETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 90
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECR-NFNGGYVCECP 345
+PS + + C+C G+ G RC + E P C+ G C +G C C
Sbjct: 91 PSSPSPLTPS--FLCTCLPGF--TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCE-RCPA 404
GW T C + ++ C A P C + G Y + +C
Sbjct: 147 PGW----TGEQC--QLRDFC----------SANP--------CVNGGVCLATYPQIQCHC 182
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDG 463
P E C+ +D++EC P C G C NT GSF+C CP G +G
Sbjct: 183 PPGFE-GHACE---------RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEG 228
Query: 464 LSC-VDADECALDPRICGN-GTC----SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGR 517
C + A C PR C N GTC + C C PGF GPD V+ D C +
Sbjct: 229 PRCELRAGPC--PPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI-GPDCE-VNPDNCVSHQ 284
Query: 518 ASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDEC-VQEPRVCPH--ACENVVGSYI 573
C + ++ C CP + G C D+DEC Q P C + C+N GS+
Sbjct: 285 CQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
C C G+ TS E++++C G CI+ GSF C C G
Sbjct: 341 CVCVSGWGGTSCE-------ENLDDC-IAATCAPGSTCIDRVGSFSCLCPPG 384
Score = 94.3 bits (224), Expect = 2e-18
Identities = 130/513 (25%), Positives = 177/513 (34%), Gaps = 80/513 (15%)
Query: 380 LQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG 439
L L + C C+ G E C PD + ++CQ G L P
Sbjct: 44 LSLGQGTCQCAPGFLG----ETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 99
Query: 440 GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGN-GTCS-NTRGGYECQCSP 497
SF C C G+ G C E P C G C G +C C P
Sbjct: 100 --------SFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMP 147
Query: 498 GFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQ 556
G+T + C D C+ C T +C CP G+ +G C RD++EC Q
Sbjct: 148 GWT---GEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQ 200
Query: 557 EPRVCPH--ACENVVGSYICKCP---EGYR-RTSAPQDSENACEDINECEEQEDLCSG-G 609
+P CP +C N +GS+ C CP EG R A C + C+ + S
Sbjct: 201 DPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFH 260
Query: 610 VCINTDGSFLCDCDAGFE-----PSEDGTDC---IDRRTGTCYRSLVSGRCEPEXXXXXX 661
+C+ G DC+ + ++G C +D T C + C +
Sbjct: 261 LCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECET 320
Query: 662 XXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWG-SECELCPAPGSPARLDLCTAVNLTPX 720
G C C G WG + CE LD C A P
Sbjct: 321 QGPPHCRNGGTCQNSAGSF---HCVCVSG--WGGTSCE--------ENLDDCIAATCAPG 367
Query: 721 XXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP----GLCAP----GRFRCVCGPGYR 772
L D+ C + P C+ G C+C PGY
Sbjct: 368 STCIDRVGSFSCLCPPGRTGLLCHLEDM--CLSQPCHGDAQCSTNPLTGSTLCLCQPGY- 424
Query: 773 PAGEVC-ADVDECAVR---PPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR-DVDEC 825
+G C D+DEC + P PC+ C NT GS++CLC GY G+ C D +EC
Sbjct: 425 -SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNEC 479
Query: 826 ERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
C + ++ C C G E G C
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLE--GQLC 510
Score = 77.4 bits (182), Expect = 2e-13
Identities = 113/396 (28%), Positives = 139/396 (35%), Gaps = 79/396 (19%)
Query: 21 YLCCCSVGHAWGAPCE--ACPPRGSPAHT-ALCGEKPGEYINPVT------NETKPIDEC 71
Y C C G G+ C+ P P A C +P Y+ N +K +D C
Sbjct: 914 YFCHCPPGFQ-GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDAC 972
Query: 72 DIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCR--GMAQCV 127
P C GTC P GF C C G+ C DVDEC PC G A C
Sbjct: 973 QSQP--CHNHGTCTPKPGGFHCACPPGF----VGLRCEGDVDECL--DQPCHPTGTAACH 1024
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGS---YRCECKPGYTL 184
+L AF C+C PG+ T E E +D C Q G C T GS + C C G+
Sbjct: 1025 SLANAFYCQCLPGH--TGQWCEVE-IDPCHSQPCFHGGTCEATAGSPLGFICHCPKGF-- 1079
Query: 185 RENVCRDVDECSRPRPVC------RNGTCENLPGAYL---CHCDDGFKAGPNNDCVDV-- 233
+ CS P C G C P C C G+ GP DC+
Sbjct: 1080 ------EGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGY-GGP--DCLTPPA 1130
Query: 234 -NECREGGMVCRNGRCRNTVG----SFRCEC---APGYTLTADG-RNCRDVDECDELPHP 284
C NG C T G FRC C +PG G + C
Sbjct: 1131 PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAG 1190
Query: 285 CGRDGNPSCTNTNGGYECSCGAG--WKLVGR--RCVDRDECKELPYVCAGGECRNFNGGY 340
C G N +GG +CS G WK RC + C EC F+G Y
Sbjct: 1191 CSGPGG----NWDGG-DCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECL-FDG-Y 1243
Query: 341 VCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHR 376
CE P C + C+D + G C +
Sbjct: 1244 DCETPPA---------CTPAYDQYCHDHFHNGHCEK 1270
Score = 71.7 bits (168), Expect = 1e-11
Identities = 108/408 (26%), Positives = 142/408 (34%), Gaps = 80/408 (19%)
Query: 472 CALDPRICGNG-TC-SNTRGGYECQCSPGF----TQGPDQTCVDVDECAEGRASCTFRCH 525
C P C NG TC S + G CQC+PGF Q PD C + C G SC
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNG-GSCQALLP 85
Query: 526 NTAG----------SFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH--ACE-NVVGSY 572
G SF CTC G+ G C+ E P C C G
Sbjct: 86 APLGLPSSPSPLTPSFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRP 141
Query: 573 ICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDG 632
C C G+ T + C N C +GGVC+ T C C GFE G
Sbjct: 142 QCSCMPGW--TGEQCQLRDFC-SANPC------VNGGVCLATYPQIQCHCPPGFE----G 188
Query: 633 TDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAA 692
C +R C++ G C P+ +A C G +
Sbjct: 189 HAC-ERDVNECFQD--PGPC-PKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCS 244
Query: 693 WGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECA 752
G C+L P S L LC + P D + D C
Sbjct: 245 NGGTCQLMPEKDSTFHLCLCPPGFIGP-----------------------DCEVNPDNCV 281
Query: 753 AIP----GLCAPG--RFRCVCGPGYRPAGEVCADVDECAVR-PPPCDQ--LCHNTDGSYD 803
+ G C G + C+C P + DVDEC + PP C C N+ GS+
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLC-PETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340
Query: 804 CLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDG 850
C+C +G+ G +C + +D+C T C + GS+ C C G
Sbjct: 341 CVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG 384
Score = 62.5 bits (145), Expect = 6e-09
Identities = 39/111 (35%), Positives = 53/111 (47%), Gaps = 14/111 (12%)
Query: 747 DVDECAAIP----GLCA--PGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D+DEC + P G C PG F C C PG+ G C +VDEC P P C +
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFE--GPRCQTEVDECLSDPCPVGASCLDLP 608
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
G++ CLC +G+ G C +V C + +QIC + + C C DG
Sbjct: 609 GAFFCLCPSGF----TGQLC-EVPLCAPNLCQPKQICKDQKDKANCLCPDG 654
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 18/117 (15%)
Query: 746 ADVDECAAIPGLCAPGR--------FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCH 796
AD +EC + P C PG F C+C PG G++C + +ECA P CH
Sbjct: 474 ADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE--GQLCEVETNECASAPCLNHADCH 529
Query: 797 NTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+ + C+C G+ G C D+DEC C + G++ C C G+E
Sbjct: 530 DLLNGFQCICLPGFS----GTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE 582
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/113 (31%), Positives = 54/113 (47%), Gaps = 14/113 (12%)
Query: 747 DVDECAAIPGL----CAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+ +ECA+ P L C F+C+C PG+ +G C D+DEC P C +
Sbjct: 513 ETNECASAPCLNHADCHDLLNGFQCICLPGF--SGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G++ C C G+E G C+ +VDEC D C + G++ C C G+
Sbjct: 571 GAFHCKCLPGFE----GPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGF 619
Score = 54.4 bits (125), Expect = 2e-06
Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 10/109 (9%)
Query: 747 DVDECAAIPGLCAPG--RFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYD 803
DV GLC + C C PG++ G +C D V+ C RP C Y
Sbjct: 896 DVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHVNPCESRPCQNGATCMAQPSGYL 953
Query: 804 CLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C C GY DG NC +++D C+ C+ G + C+C G+
Sbjct: 954 CQCAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGF 998
Score = 48.4 bits (110), Expect = 1e-04
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 8/97 (8%)
Query: 757 LCAPGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 815
L PG F C+C PGY G C AD +EC +P C + ++ CLC G E
Sbjct: 453 LNTPGSFNCLCPPGY--TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE---- 506
Query: 816 GANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C + +EC C + ++C C G+
Sbjct: 507 GQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 543
Score = 42.3 bits (95), Expect = 0.007
Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 10/101 (9%)
Query: 749 DECAAIPGLCAPGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCR 807
D C G C R CVC G+ G C A++ C P C+ Y+C C
Sbjct: 663 DNCTCHHGHCQ--RSSCVCDVGW--TGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 718
Query: 808 TGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSC 847
TGY G C ++ C C+ + G Y C+C
Sbjct: 719 TGY----TGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 755
Score = 40.3 bits (90), Expect = 0.028
Identities = 26/101 (25%), Positives = 37/101 (36%), Gaps = 7/101 (6%)
Query: 759 APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
+PG + C C P + G C D C P C N G++ CLC G++
Sbjct: 747 SPGGYYCTCPPSH--TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEG 804
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
R C + C ++ C C GY G +C
Sbjct: 805 KLR--PSCADSPCRNRATCQDSPQGPRCLCPTGY--TGGSC 841
Score = 39.9 bits (89), Expect = 0.038
Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 18/106 (16%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DV 822
RC+C GY G +D CA +P P + C T S+ CLC G+ G C +
Sbjct: 829 RCLCPTGYT-GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGW----TGPLCNLPL 883
Query: 823 DECERD--------THTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
C++ + C +C ++ SY C C G++ G C
Sbjct: 884 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLC 927
Score = 35.1 bits (77), Expect = 1.1
Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 14/73 (19%)
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDG 850
LC ++ SY C C G++ G+ C+D V+ CE + CQ C Y C C G
Sbjct: 906 LCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPG 959
Query: 851 YE-----KRGDAC 858
Y+ K DAC
Sbjct: 960 YDGQNCSKELDAC 972
>AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2005
Score = 193 bits (470), Expect = 3e-48
Identities = 167/563 (29%), Positives = 242/563 (42%), Gaps = 80/563 (14%)
Query: 92 CGCDHGYEHDNTSHLCRDVDEC---SWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD 148
C C GY T H +D+DEC G PC C+N PG+F C CPPGY T S
Sbjct: 420 CLCQPGYSGP-TCH--QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGS-- 472
Query: 149 ECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGT 206
CE D +EC Q C + + ++ C C PG L +C + +EC+ P +
Sbjct: 473 RCEADHNECLSQPCHPGSTCLDLLATFHCLCPPG--LEGQLCEVETNECA-SAPCLNHAD 529
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTL 265
C +L + C C GF + D++ECR C N G+C++ G+F C+C PG+
Sbjct: 530 CHDLLNGFQCICLPGFSGTRCEE--DIDECRSS--PCANGGQCQDQPGAFHCKCLPGF-- 583
Query: 266 TADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKEL 324
+G C+ +VDEC P P G SC + G + C C +G+ G+ C + C
Sbjct: 584 --EGPRCQTEVDECLSDPCPVG----ASCLDLPGAFFCLCPSGF--TGQLC-EVPLC--A 632
Query: 325 PYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRAR---PL 380
P +C + C++ C CP D + E C+ G C R+ +
Sbjct: 633 PNLCQPKQICKDQKDKANCLCP-----DGSPGCAPPEDNCTCHH----GHCQRSSCVCDV 683
Query: 381 QLARPEC------CCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP 434
PEC C S A G C P + + C G P ++++ C P
Sbjct: 684 GWTGPECEAELGGCISAPCAHGGTC----YPQPSGYNCTCPTGYTGPTCSEEMTACHSGP 739
Query: 435 DVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYE 492
C+ GG C + G + C CP + G C D C P G GTC N G +
Sbjct: 740 --CLNGGSCNPSPGGYYCTCPPSHT----GPQCQTSTDYCVSAPCFNG-GTCVNRPGTFS 792
Query: 493 CQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI- 551
C C+ GF QGP CA+ C ++ RC CP GY G C+ +
Sbjct: 793 CLCAMGF-QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYT----GGSCQTLM 847
Query: 552 DECVQEPRVCPH--ACENVVGSYICKCPEGYR--RTSAPQDSENACEDINECEEQEDLC- 606
D C Q+P CP C S+ C C +G+ + P S +++ + LC
Sbjct: 848 DLCAQKP--CPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAA-LSQGIDVSSLCH 904
Query: 607 SGGVCINTDGSFLCDCDAGFEPS 629
+GG+C+++ S+ C C GF+ S
Sbjct: 905 NGGLCVDSGPSYFCHCPPGFQGS 927
Score = 186 bits (454), Expect = 2e-46
Identities = 191/641 (29%), Positives = 255/641 (39%), Gaps = 118/641 (18%)
Query: 33 APCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKP----GTCHDTPT 88
A C P GS LC +PG Y P ++ +DEC + Q P G+C +TP
Sbjct: 407 AQCSTNPLTGS----TLCLCQPG-YSGPTCHQD--LDECLMAQQGPSPCEHGGSCLNTPG 459
Query: 89 GFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
F C C GY T C D +EC PC + C++L F C CPPG L L
Sbjct: 460 SFNCLCPPGY----TGSRCEADHNECL--SQPCHPGSTCLDLLATFHCLCPPG--LEGQL 511
Query: 148 DECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTC 207
E E +EC +H DC + + ++C C PG++ D+DEC R P G C
Sbjct: 512 CEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS-GTRCEEDIDEC-RSSPCANGGQC 568
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYT-- 264
++ PGA+ C C GF+ GP +V+EC C G C + G+F C C G+T
Sbjct: 569 QDQPGAFHCKCLPGFE-GPRCQ-TEVDECLSD--PCPVGASCLDLPGAFFCLCPSGFTGQ 624
Query: 265 ----------LTADGRNCRDVDECDELPHPCGRDG----NPSCTNTNGGYE---CSCGAG 307
L + C+D + P G G +CT +G + C C G
Sbjct: 625 LCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVG 684
Query: 308 WKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
W G C + C P CA GG C GY C CP G+ T C E C
Sbjct: 685 W--TGPECEAELGGCISAP--CAHGGTCYPQPSGYNCTCPTGY----TGPTC-SEEMTAC 735
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
+ +G C L C S G G YC CP + P
Sbjct: 736 H----SGPC-------LNGGSCNPSPG---GYYC-TCPPSHTG------------PQCQT 768
Query: 426 DLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVD--ADECALDPRICGN- 481
D C P C GG CVN G+F C C G+ G C CA P C N
Sbjct: 769 STDYCVSAP--CFNGGTCVNRPGTFSCLCAMGF----QGPRCEGKLRPSCADSP--CRNR 820
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA- 540
TC ++ G C C G+T G QT +D+ CA+ C T SF C C G+
Sbjct: 821 ATCQDSPQGPRCLCPTGYTGGSCQTLMDL--CAQKPCPRNSHCLQTGPSFHCLCLQGWTG 878
Query: 541 ----VAADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENACE 594
+ + + + +C + C + SY C CP G+ + S QD N CE
Sbjct: 879 PLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF-QGSLCQDHVNPCE 937
Query: 595 DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
C+ +G C+ +LC C G+ DG +C
Sbjct: 938 S-RPCQ------NGATCMAQPSGYLCQCAPGY----DGQNC 967
Score = 178 bits (433), Expect = 8e-44
Identities = 182/654 (27%), Positives = 268/654 (40%), Gaps = 107/654 (16%)
Query: 21 YLCCCSVGHAWGAPCEA-----CPP----RGSPAHTALCGEKPGEYINPVTNETKPI-DE 70
+LC C G G C+A CPP + H G + T E + D
Sbjct: 103 FLCTCLPGFT-GERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDF 161
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNL 129
C P + G C T QC C G+E H C RDV+EC PC C N
Sbjct: 162 CSANPCV-NGGVCLATYPQIQCHCPPGFE----GHACERDVNECFQDPGPCPKGTSCHNT 216
Query: 130 PGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCR----NTIGSYRCECKPGYTL 184
G+F+C CP G P CE C + + G C+ + C C PG+ +
Sbjct: 217 LGSFQCLCPVGQE-GP---RCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGF-I 271
Query: 185 RENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCV-DVNECR-EGGM 241
+ + D C + C+NG TC++ Y C C + + DC DV+EC +G
Sbjct: 272 GPDCEVNPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGW---DCSEDVDECEAQGPP 326
Query: 242 VCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGG 299
CRNG C+N+ GSF C C G+ G +C + +D+C + C +C + G
Sbjct: 327 HCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDC--IAATCA--PGSTCIDRVGS 378
Query: 300 YECSCGAGWKLVGRRCVDRDECKELPYVCAG-GECRN--FNGGYVCECPAGWRFDKTAAV 356
+ C C G G C D C P C G +C G +C C G+ +
Sbjct: 379 FSCLCPPG--RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTLCLCQPGY----SGPT 430
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
C + E C A+ Q P C G + C P F +C
Sbjct: 431 CHQDLDE----------CLMAQ--QGPSP---CEHGGS----CLNTP----GSFNCLCPP 467
Query: 417 GMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALD 475
G D +EC +P G C++ +F C CP G +G C V+ +ECA
Sbjct: 468 GYTGSRCEADHNECLSQP-CHPGSTCLDLLATFHCLCPPGL----EGQLCEVETNECASA 522
Query: 476 PRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
P + + C + G++C C PGF+ + D+DEC + +C + G+F C C
Sbjct: 523 PCL-NHADCHDLLNGFQCICLPGFSGTRCEE--DIDECRSSPCANGGQCQDQPGAFHCKC 579
Query: 536 PYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGY--RRTSAPQDSENA 592
G+ +G C+ ++DEC+ +P +C ++ G++ C CP G+ + P + N
Sbjct: 580 LPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNL 635
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS 646
C+ C++Q+D + C+ DGS G P ED C G C RS
Sbjct: 636 CQPKQICKDQKDKAN---CLCPDGS------PGCAPPEDNCTC---HHGHCQRS 677
Score = 171 bits (415), Expect = 1e-41
Identities = 169/571 (29%), Positives = 222/571 (38%), Gaps = 101/571 (17%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P G C D P F C C G+E +VDEC PC A C+
Sbjct: 554 IDECRSSP-CANGGQCQDQPGAFHCKCLPGFEGPRCQ---TEVDECL--SDPCPVGASCL 607
Query: 128 NLPGAFECRCPPGYR--------LTPSLDECEDVDECGDQR-----ICDHGDCRNTIGSY 174
+LPGAF C CP G+ P+L C+ C DQ+ +C G
Sbjct: 608 DLPGAFFCLCPSGFTGQLCEVPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPED 665
Query: 175 RCECKPGYTLRENVCRDVD----ECSRP------RPVCRNGTCENLPGAYLCHCDDGFKA 224
C C G+ R + DV EC P GTC P Y C C G+
Sbjct: 666 NCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY-T 724
Query: 225 GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPH 283
GP C + G G C + G + C C P +T G C+ D C +
Sbjct: 725 GPT--CSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT----GPQCQTSTDYC--VSA 776
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVD--RDECKELPYVCAG-GECRNFNGGY 340
PC G +C N G + C C G++ G RC R C + P C C++ G
Sbjct: 777 PCFNGG--TCVNRPGTFSCLCAMGFQ--GPRCEGKLRPSCADSP--CRNRATCQDSPQGP 830
Query: 341 VCECPAGWR-------FDKTA-------AVCVDERKE---LCYDEWEAGRCHRARPLQLA 383
C CP G+ D A + C+ LC W C+ PL
Sbjct: 831 RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNL--PLSSC 888
Query: 384 RPECCCSEGAAWGRYCER---CPAPDSAEFMRICQGGMGRPNLTQD-LDECRVRPDVCVG 439
+ + S+G C C + F G G +L QD ++ C RP C
Sbjct: 889 Q-KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQG--SLCQDHVNPCESRP--CQN 943
Query: 440 GR-CVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGN-GTCSNTRGGYECQCS 496
G C+ + C+C GY DG +C + D C P C N GTC+ GG+ C C
Sbjct: 944 GATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQP--CHNHGTCTPKPGGFHCACP 997
Query: 497 PGFTQGPDQTCV-DVDECAEG--RASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DID 552
PGF C DVDEC + + T CH+ A +F C C G+ G C +ID
Sbjct: 998 PGFV---GLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT----GQWCEVEID 1050
Query: 553 ECVQEPRVCPHACENVVGS---YICKCPEGY 580
C +P CE GS +IC CP+G+
Sbjct: 1051 PCHSQPCFHGGTCEATAGSPLGFICHCPKGF 1081
Score = 167 bits (405), Expect = 2e-40
Identities = 186/634 (29%), Positives = 259/634 (40%), Gaps = 125/634 (19%)
Query: 66 KPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+ ++EC P C GT CH+T FQC C G E C E G P RG +
Sbjct: 195 RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPR----C----ELRAGPCPPRGCS 246
Query: 125 Q---CVNLP---GAFE-CRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRC 176
C +P F C CPPG+ + P +CE + D C + + G C++ + +Y C
Sbjct: 247 NGGTCQLMPEKDSTFHLCLCPPGF-IGP---DCEVNPDNCVSHQCQNGGTCQDGLDTYTC 302
Query: 177 ECKPGYTLRENVCRDVDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVN 234
C +T + DVDEC ++ P CRNG TC+N G++ C C G+ G + +++
Sbjct: 303 LCPETWT-GWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGW--GGTSCEENLD 359
Query: 235 ECREGGMVCRNGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+C C G C + VGSF C C PG T G C D C L PC D S
Sbjct: 360 DCIAA--TCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMC--LSQPCHGDAQCST 411
Query: 294 TNTNGGYECSCGAGWKLVGRRC-VDRDEC---KELPYVCA-GGECRNFNGGYVCECPAGW 348
G C C G+ G C D DEC ++ P C GG C N G + C CP G+
Sbjct: 412 NPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 469
Query: 349 RFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSA 408
T + C + E C + CH P C + A
Sbjct: 470 ----TGSRCEADHNE-CLSQ----PCH---------PGSTCLDLLA-------------- 497
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCV 467
F +C G+ + +EC P C+ C + F+C C G+ G C
Sbjct: 498 TFHCLCPPGLEGQLCEVETNECASAP--CLNHADCHDLLNGFQCICLPGF----SGTRCE 551
Query: 468 -DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
D DEC P C NG C + G + C+C PGF +GP + +VDEC C
Sbjct: 552 EDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF-EGP-RCQTEVDECLSDPCPVGASCL 607
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRT 583
+ G+F C CP G+ G C ++ C P +C C++ C CP+G
Sbjct: 608 DLPGAFFCLCPSGFT----GQLC-EVPLCA--PNLCQPKQICKDQKDKANCLCPDGSPGC 660
Query: 584 SAPQDS---------ENACE-DIN----ECEEQEDLC------SGGVCINTDGSFLCDCD 623
+ P+D+ ++C D+ ECE + C GG C + C C
Sbjct: 661 APPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 720
Query: 624 AGFEP---SEDGTDCIDRRTGTCYRSLVSGRCEP 654
G+ SE+ T C +G C L G C P
Sbjct: 721 TGYTGPTCSEEMTAC---HSGPC---LNGGSCNP 748
Score = 146 bits (354), Expect = 3e-34
Identities = 154/527 (29%), Positives = 212/527 (40%), Gaps = 105/527 (19%)
Query: 165 GDCRN-TIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCE-------NLPGA-- 213
G C + ++G C+C PG+ L E C+ D C + +C+NG +C+ LP +
Sbjct: 41 GTCLSLSLGQGTCQCAPGF-LGET-CQFPDPCQNAQ-LCQNGGSCQALLPAPLGLPSSPS 97
Query: 214 -----YLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCR-NTVGSFRCECAPGYTLTA 267
+LC C GF G + C + GRC G +C C PG+T
Sbjct: 98 PLTPSFLCTCLPGF-TGERCQAQLEDPCPPS-FCSKRGRCHIQASGRPQCSCMPGWT--- 152
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV-DRDECKELPY 326
G C+ D C +PC G C T +C C G++ G C D +EC + P
Sbjct: 153 -GEQCQLRDFCSA--NPCVNGG--VCLATYPQIQCHCPPGFE--GHACERDVNECFQDPG 205
Query: 327 VCAGG-ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARP 385
C G C N G + C CP G + C E AG C P
Sbjct: 206 PCPKGTSCHNTLGSFQCLCPVG------------QEGPRC--ELRAGPC----------P 241
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN- 444
CS G C+ P DS + +C G P +C V PD CV +C N
Sbjct: 242 PRGCSNGGT----CQLMPEKDSTFHLCLCPPGFIGP-------DCEVNPDNCVSHQCQNG 290
Query: 445 ---TDG--SFRCECPDGYVLAPDGLSCV-DADEC-ALDPRICGNG-TCSNTRGGYECQCS 496
DG ++ C CP+ + G C D DEC A P C NG TC N+ G + C C
Sbjct: 291 GTCQDGLDTYTCLCPETWT----GWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCV 346
Query: 497 PGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
G+ G ++D+C + C + GSF C CP G G+ C D C+
Sbjct: 347 SGW--GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMCLS 400
Query: 557 EPRVCPHACEN--VVGSYICKCPEGYRRTSAPQDSEN---ACEDINECEEQEDLCSGGVC 611
+P C + GS +C C GY + QD + A + + CE GG C
Sbjct: 401 QPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH------GGSC 454
Query: 612 INTDGSFLCDCDAGFEPSE---DGTDCIDRRT---GTCYRSLVSGRC 652
+NT GSF C C G+ S D +C+ + TC L + C
Sbjct: 455 LNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 501
Score = 121 bits (292), Expect = 1e-26
Identities = 102/340 (30%), Positives = 139/340 (40%), Gaps = 44/340 (12%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGY 141
TC D+P G +C C GY + L +D C+ + PC + C+ +F C C G+
Sbjct: 822 TCQDSPQGPRCLCPTGYTGGSCQTL---MDLCA--QKPCPRNSHCLQTGPSFHCLCLQGW 876
Query: 142 R---LTPSLDECEDV---DECGDQRICDHGD-CRNTIGSYRCECKPGYTLRENVCRD-VD 193
L C+ +C +G C ++ SY C C PG+ + ++C+D V+
Sbjct: 877 TGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF--QGSLCQDHVN 934
Query: 194 EC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRN 250
C SRP C+NG TC P YLC C G+ N +++ C+ C N G C
Sbjct: 935 PCESRP---CQNGATCMAQPSGYLCQCAPGYDG--QNCSKELDACQ--SQPCHNHGTCTP 987
Query: 251 TVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
G F C C PG+ G C DVDEC L PC G +C + + C C G
Sbjct: 988 KPGGFHCACPPGFV----GLRCEGDVDEC--LDQPCHPTGTAACHSLANAFYCQCLPGH- 1040
Query: 310 LVGRRC-VDRDECKELPYVCAGGECRNFNG---GYVCECPAGWRFDKTAAVCVDERKELC 365
G+ C V+ D C P GG C G G++C CP G+ C
Sbjct: 1041 -TGQWCEVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCPKGFE----GPTCSHRAPSCG 1094
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
+ G P P C C G G C PAP
Sbjct: 1095 FHHCHHGGLCLPSPKPGFPPRCACLSGYG-GPDCLTPPAP 1133
Score = 105 bits (251), Expect = 9e-22
Identities = 83/256 (32%), Positives = 114/256 (44%), Gaps = 44/256 (17%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
++ C+ P C+ G TC P+G+ C C GY+ N S +++D C PC C
Sbjct: 933 VNPCESRP--CQNGATCMAQPSGYLCQCAPGYDGQNCS---KELDACQ--SQPCHNHGTC 985
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGD--CRNTIGSYRCECKPGYT 183
PG F C CPPG+ L CE DVDEC DQ G C + ++ C+C PG+T
Sbjct: 986 TPKPGGFHCACPPGF---VGL-RCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT 1041
Query: 184 LRENVCR-DVDECSRPRPVCRNGTCENLPGA---YLCHCDDGFKAGPNND----CVDVNE 235
C ++D C +P GTCE G+ ++CHC GF+ GP +
Sbjct: 1042 --GQWCEVEIDPC-HSQPCFHGGTCEATAGSPLGFICHCPKGFE-GPTCSHRAPSCGFHH 1097
Query: 236 CREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE---CDELPHPCGRDGNPS 292
C GG+ + + RC C GY G +C C P PC +G S
Sbjct: 1098 CHHGGLCLPSPKPGFPP---RCACLSGY----GGPDCLTPPAPKGCGP-PSPCLYNG--S 1147
Query: 293 CTNTNG----GYECSC 304
C+ T G G+ CSC
Sbjct: 1148 CSETTGLGGPGFRCSC 1163
Score = 96.3 bits (229), Expect = 4e-19
Identities = 119/412 (28%), Positives = 163/412 (39%), Gaps = 91/412 (22%)
Query: 243 CRNG-RCRN-TVGSFRCECAPGYTLTADGRNCRDVDECDE-------------LPHPCGR 287
C NG C + ++G C+CAPG+ G C+ D C LP P G
Sbjct: 37 CANGGTCLSLSLGQGTCQCAPGFL----GETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 92
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECR-NFNGGYVCECP 345
+PS + + C+C G+ G RC + E P C+ G C +G C C
Sbjct: 93 PSSPSPLTPS--FLCTCLPGF--TGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCM 148
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCE-RCPA 404
GW T C + ++ C A P C + G Y + +C
Sbjct: 149 PGW----TGEQC--QLRDFC----------SANP--------CVNGGVCLATYPQIQCHC 184
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDG 463
P E C+ +D++EC P C G C NT GSF+C CP G +G
Sbjct: 185 PPGFE-GHACE---------RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEG 230
Query: 464 LSC-VDADECALDPRICGN-GTC----SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGR 517
C + A C PR C N GTC + C C PGF GPD V+ D C +
Sbjct: 231 PRCELRAGPC--PPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI-GPDCE-VNPDNCVSHQ 286
Query: 518 ASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDEC-VQEPRVCPH--ACENVVGSYI 573
C + ++ C CP + G C D+DEC Q P C + C+N GS+
Sbjct: 287 CQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFH 342
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
C C G+ TS E++++C G CI+ GSF C C G
Sbjct: 343 CVCVSGWGGTSCE-------ENLDDC-IAATCAPGSTCIDRVGSFSCLCPPG 386
Score = 94.3 bits (224), Expect = 2e-18
Identities = 130/513 (25%), Positives = 177/513 (34%), Gaps = 80/513 (15%)
Query: 380 LQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG 439
L L + C C+ G E C PD + ++CQ G L P
Sbjct: 46 LSLGQGTCQCAPGFLG----ETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 101
Query: 440 GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGN-GTCS-NTRGGYECQCSP 497
SF C C G+ G C E P C G C G +C C P
Sbjct: 102 --------SFLCTCLPGFT----GERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMP 149
Query: 498 GFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQ 556
G+T + C D C+ C T +C CP G+ +G C RD++EC Q
Sbjct: 150 GWT---GEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQ 202
Query: 557 EPRVCPH--ACENVVGSYICKCP---EGYR-RTSAPQDSENACEDINECEEQEDLCSG-G 609
+P CP +C N +GS+ C CP EG R A C + C+ + S
Sbjct: 203 DPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFH 262
Query: 610 VCINTDGSFLCDCDAGFE-----PSEDGTDC---IDRRTGTCYRSLVSGRCEPEXXXXXX 661
+C+ G DC+ + ++G C +D T C + C +
Sbjct: 263 LCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEA 322
Query: 662 XXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWG-SECELCPAPGSPARLDLCTAVNLTPX 720
G C C G WG + CE LD C A P
Sbjct: 323 QGPPHCRNGGTCQNSAGSF---HCVCVSG--WGGTSCE--------ENLDDCIAATCAPG 369
Query: 721 XXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP----GLCAP----GRFRCVCGPGYR 772
L D+ C + P C+ G C+C PGY
Sbjct: 370 STCIDRVGSFSCLCPPGRTGLLCHLEDM--CLSQPCHGDAQCSTNPLTGSTLCLCQPGY- 426
Query: 773 PAGEVC-ADVDECAVR---PPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR-DVDEC 825
+G C D+DEC + P PC+ C NT GS++CLC GY G+ C D +EC
Sbjct: 427 -SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNEC 481
Query: 826 ERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
C + ++ C C G E G C
Sbjct: 482 LSQPCHPGSTCLDLLATFHCLCPPGLE--GQLC 512
Score = 77.4 bits (182), Expect = 2e-13
Identities = 113/396 (28%), Positives = 139/396 (35%), Gaps = 79/396 (19%)
Query: 21 YLCCCSVGHAWGAPCE--ACPPRGSPAHT-ALCGEKPGEYINPVT------NETKPIDEC 71
Y C C G G+ C+ P P A C +P Y+ N +K +D C
Sbjct: 916 YFCHCPPGFQ-GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDAC 974
Query: 72 DIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCR--GMAQCV 127
P C GTC P GF C C G+ C DVDEC PC G A C
Sbjct: 975 QSQP--CHNHGTCTPKPGGFHCACPPGF----VGLRCEGDVDECL--DQPCHPTGTAACH 1026
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGS---YRCECKPGYTL 184
+L AF C+C PG+ T E E +D C Q G C T GS + C C G+
Sbjct: 1027 SLANAFYCQCLPGH--TGQWCEVE-IDPCHSQPCFHGGTCEATAGSPLGFICHCPKGF-- 1081
Query: 185 RENVCRDVDECSRPRPVC------RNGTCENLPGAYL---CHCDDGFKAGPNNDCVDV-- 233
+ CS P C G C P C C G+ GP DC+
Sbjct: 1082 ------EGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGY-GGP--DCLTPPA 1132
Query: 234 -NECREGGMVCRNGRCRNTVG----SFRCEC---APGYTLTADG-RNCRDVDECDELPHP 284
C NG C T G FRC C +PG G + C
Sbjct: 1133 PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAG 1192
Query: 285 CGRDGNPSCTNTNGGYECSCGAG--WKLVGR--RCVDRDECKELPYVCAGGECRNFNGGY 340
C G N +GG +CS G WK RC + C EC F+G Y
Sbjct: 1193 CSGPGG----NWDGG-DCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECL-FDG-Y 1245
Query: 341 VCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHR 376
CE P C + C+D + G C +
Sbjct: 1246 DCETPPA---------CTPAYDQYCHDHFHNGHCEK 1272
Score = 71.7 bits (168), Expect = 1e-11
Identities = 109/408 (26%), Positives = 142/408 (34%), Gaps = 80/408 (19%)
Query: 472 CALDPRICGNG-TC-SNTRGGYECQCSPGF----TQGPDQTCVDVDECAEGRASCTFRCH 525
C P C NG TC S + G CQC+PGF Q PD C + C G SC
Sbjct: 30 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNG-GSCQALLP 87
Query: 526 NTAG----------SFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH--ACE-NVVGSY 572
G SF CTC G+ G C+ E P C C G
Sbjct: 88 APLGLPSSPSPLTPSFLCTCLPGFT----GERCQAQLEDPCPPSFCSKRGRCHIQASGRP 143
Query: 573 ICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDG 632
C C G+ T + C N C +GGVC+ T C C GFE G
Sbjct: 144 QCSCMPGW--TGEQCQLRDFC-SANPC------VNGGVCLATYPQIQCHCPPGFE----G 190
Query: 633 TDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAA 692
C +R C++ G C P+ +A C G +
Sbjct: 191 HAC-ERDVNECFQD--PGPC-PKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCS 246
Query: 693 WGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECA 752
G C+L P S L LC + P D + D C
Sbjct: 247 NGGTCQLMPEKDSTFHLCLCPPGFIGP-----------------------DCEVNPDNCV 283
Query: 753 AIP----GLCAPG--RFRCVCGPGYRPAGEVCADVDEC-AVRPPPCDQ--LCHNTDGSYD 803
+ G C G + C+C P + DVDEC A PP C C N+ GS+
Sbjct: 284 SHQCQNGGTCQDGLDTYTCLC-PETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFH 342
Query: 804 CLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDG 850
C+C +G+ G +C + +D+C T C + GS+ C C G
Sbjct: 343 CVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG 386
Score = 62.5 bits (145), Expect = 6e-09
Identities = 39/111 (35%), Positives = 53/111 (47%), Gaps = 14/111 (12%)
Query: 747 DVDECAAIP----GLCA--PGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D+DEC + P G C PG F C C PG+ G C +VDEC P P C +
Sbjct: 553 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFE--GPRCQTEVDECLSDPCPVGASCLDLP 610
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
G++ CLC +G+ G C +V C + +QIC + + C C DG
Sbjct: 611 GAFFCLCPSGF----TGQLC-EVPLCAPNLCQPKQICKDQKDKANCLCPDG 656
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 18/117 (15%)
Query: 746 ADVDECAAIPGLCAPGR--------FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCH 796
AD +EC + P C PG F C+C PG G++C + +ECA P CH
Sbjct: 476 ADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE--GQLCEVETNECASAPCLNHADCH 531
Query: 797 NTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+ + C+C G+ G C D+DEC C + G++ C C G+E
Sbjct: 532 DLLNGFQCICLPGFS----GTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE 584
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/113 (31%), Positives = 54/113 (47%), Gaps = 14/113 (12%)
Query: 747 DVDECAAIPGL----CAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+ +ECA+ P L C F+C+C PG+ +G C D+DEC P C +
Sbjct: 515 ETNECASAPCLNHADCHDLLNGFQCICLPGF--SGTRCEEDIDECRSSPCANGGQCQDQP 572
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G++ C C G+E G C+ +VDEC D C + G++ C C G+
Sbjct: 573 GAFHCKCLPGFE----GPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGF 621
Score = 54.4 bits (125), Expect = 2e-06
Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 10/109 (9%)
Query: 747 DVDECAAIPGLCAPG--RFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYD 803
DV GLC + C C PG++ G +C D V+ C RP C Y
Sbjct: 898 DVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHVNPCESRPCQNGATCMAQPSGYL 955
Query: 804 CLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C C GY DG NC +++D C+ C+ G + C+C G+
Sbjct: 956 CQCAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGF 1000
Score = 48.4 bits (110), Expect = 1e-04
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 8/97 (8%)
Query: 757 LCAPGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 815
L PG F C+C PGY G C AD +EC +P C + ++ CLC G E
Sbjct: 455 LNTPGSFNCLCPPGY--TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE---- 508
Query: 816 GANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C + +EC C + ++C C G+
Sbjct: 509 GQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 545
Score = 42.3 bits (95), Expect = 0.007
Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 10/101 (9%)
Query: 749 DECAAIPGLCAPGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCR 807
D C G C R CVC G+ G C A++ C P C+ Y+C C
Sbjct: 665 DNCTCHHGHCQ--RSSCVCDVGW--TGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 720
Query: 808 TGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSC 847
TGY G C ++ C C+ + G Y C+C
Sbjct: 721 TGY----TGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 757
Score = 40.3 bits (90), Expect = 0.028
Identities = 26/101 (25%), Positives = 37/101 (36%), Gaps = 7/101 (6%)
Query: 759 APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
+PG + C C P + G C D C P C N G++ CLC G++
Sbjct: 749 SPGGYYCTCPPSH--TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEG 806
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
R C + C ++ C C GY G +C
Sbjct: 807 KLR--PSCADSPCRNRATCQDSPQGPRCLCPTGY--TGGSC 843
Score = 39.9 bits (89), Expect = 0.038
Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 18/106 (16%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DV 822
RC+C GY G +D CA +P P + C T S+ CLC G+ G C +
Sbjct: 831 RCLCPTGYT-GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGW----TGPLCNLPL 885
Query: 823 DECERD--------THTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
C++ + C +C ++ SY C C G++ G C
Sbjct: 886 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLC 929
Score = 35.1 bits (77), Expect = 1.1
Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 14/73 (19%)
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDG 850
LC ++ SY C C G++ G+ C+D V+ CE + CQ C Y C C G
Sbjct: 908 LCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPG 961
Query: 851 YE-----KRGDAC 858
Y+ K DAC
Sbjct: 962 YDGQNCSKELDAC 974
>D86566-1|BAA13116.1| 955|Homo sapiens notch related protein
protein.
Length = 955
Score = 192 bits (469), Expect = 3e-48
Identities = 167/563 (29%), Positives = 241/563 (42%), Gaps = 80/563 (14%)
Query: 92 CGCDHGYEHDNTSHLCRDVDEC---SWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD 148
C C GY T H +D+DEC G PC C+N PG+F C CPPGY T S
Sbjct: 418 CLCQPGYSGP-TCH--QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGS-- 470
Query: 149 ECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGT 206
CE D +EC Q C + + ++ C C PG L +C + +EC+ P +
Sbjct: 471 RCEADHNECLSQPCHPGSTCLDLLATFHCLCPPG--LEGQLCEVETNECA-SAPCLNHAD 527
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTL 265
C +L + C C GF + D++ECR C N G+C++ G+F C+C PG+
Sbjct: 528 CHDLLNGFQCICLPGFSGTRCEE--DIDECRSS--PCANGGQCQDQPGAFHCKCLPGF-- 581
Query: 266 TADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKEL 324
+G C+ +VDEC P P G SC + G + C C +G+ G+ C + C
Sbjct: 582 --EGPRCQTEVDECLSDPCPVG----ASCLDLPGAFFCLCPSGF--TGQLC-EVPLC--A 630
Query: 325 PYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRAR---PL 380
P +C + C++ C CP D + E C+ G C R+ +
Sbjct: 631 PNLCQPKQICKDQKDKANCLCP-----DGSPGCAPPEDNCTCHH----GHCQRSSCVCDV 681
Query: 381 QLARPEC------CCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP 434
PEC C S A G C P + + C G P ++++ C P
Sbjct: 682 GWTGPECEAELGGCISAPCAHGGTC----YPQPSGYNCTCPTGYTGPTCSEEMTACHSGP 737
Query: 435 DVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYE 492
C+ GG C + G + C CP + G C D C P G GTC N G +
Sbjct: 738 --CLNGGSCNPSPGGYYCTCPPSHT----GPQCQTSTDYCVSAPCFNG-GTCVNRPGTFS 790
Query: 493 CQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI- 551
C C+ GF QGP CA+ C ++ RC CP GY G C+ +
Sbjct: 791 CLCAMGF-QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYT----GGSCQTLM 845
Query: 552 DECVQEPRVCPH--ACENVVGSYICKCPEGYR--RTSAPQDSENACEDINECEEQEDLC- 606
D C Q P CP C S+ C C +G+ + P S +++ + LC
Sbjct: 846 DLCAQRP--CPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAA-LSQGIDVSSLCH 902
Query: 607 SGGVCINTDGSFLCDCDAGFEPS 629
+GG+C+++ S+ C C GF+ S
Sbjct: 903 NGGLCVDSGPSYFCHCPPGFQGS 925
Score = 179 bits (435), Expect = 4e-44
Identities = 186/626 (29%), Positives = 248/626 (39%), Gaps = 114/626 (18%)
Query: 33 APCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKP----GTCHDTPT 88
A C P GS LC +PG Y P ++ +DEC + Q P G+C +TP
Sbjct: 405 AQCSTNPLTGS----TLCLCQPG-YSGPTCHQD--LDECLMAQQGPSPCEHGGSCLNTPG 457
Query: 89 GFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
F C C GY T C D +EC PC + C++L F C CPPG L L
Sbjct: 458 SFNCLCPPGY----TGSRCEADHNECL--SQPCHPGSTCLDLLATFHCLCPPG--LEGQL 509
Query: 148 DECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTC 207
E E +EC +H DC + + ++C C PG++ D+DEC R P G C
Sbjct: 510 CEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS-GTRCEEDIDEC-RSSPCANGGQC 566
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYT-- 264
++ PGA+ C C GF+ GP +V+EC C G C + G+F C C G+T
Sbjct: 567 QDQPGAFHCKCLPGFE-GPRCQ-TEVDECLSD--PCPVGASCLDLPGAFFCLCPSGFTGQ 622
Query: 265 ----------LTADGRNCRDVDECDELPHPCGRDG----NPSCTNTNGGYE---CSCGAG 307
L + C+D + P G G +CT +G + C C G
Sbjct: 623 LCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVG 682
Query: 308 WKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
W G C + C P CA GG C GY C CP G+ T C E C
Sbjct: 683 W--TGPECEAELGGCISAP--CAHGGTCYPQPSGYNCTCPTGY----TGPTC-SEEMTAC 733
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
+ +G C L C S G G YC CP + P
Sbjct: 734 H----SGPC-------LNGGSCNPSPG---GYYC-TCPPSHTG------------PQCQT 766
Query: 426 DLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVD--ADECALDPRICGN- 481
D C P C GG CVN G+F C C G+ G C CA P C N
Sbjct: 767 STDYCVSAP--CFNGGTCVNRPGTFSCLCAMGF----QGPRCEGKLRPSCADSP--CRNR 818
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA- 540
TC ++ G C C G+T G QT +D+ CA+ C T SF C C G+
Sbjct: 819 ATCQDSPQGPRCLCPTGYTGGSCQTLMDL--CAQRPCPRNSHCLQTGPSFHCLCLQGWTG 876
Query: 541 ----VAADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENACE 594
+ + + + +C + C + SY C CP G+ + S QD N CE
Sbjct: 877 PLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF-QGSLCQDHVNPCE 935
Query: 595 DINECEEQEDLCSGGVCINTDGSFLC 620
C+ +G C+ +LC
Sbjct: 936 S-RPCQ------NGATCMAQPSGYLC 954
Score = 178 bits (433), Expect = 8e-44
Identities = 182/654 (27%), Positives = 268/654 (40%), Gaps = 107/654 (16%)
Query: 21 YLCCCSVGHAWGAPCEA-----CPP----RGSPAHTALCGEKPGEYINPVTNETKPI-DE 70
+LC C G G C+A CPP + H G + T E + D
Sbjct: 101 FLCTCLPGFT-GERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDF 159
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNL 129
C P + G C T QC C G+E H C RDV+EC PC C N
Sbjct: 160 CSANPCV-NGGVCLATYPQIQCHCPPGFE----GHACERDVNECFQDPGPCPKGTSCHNT 214
Query: 130 PGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCR----NTIGSYRCECKPGYTL 184
G+F+C CP G P CE C + + G C+ + C C PG+ +
Sbjct: 215 LGSFQCLCPVGQE-GP---RCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGF-I 269
Query: 185 RENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCV-DVNECR-EGGM 241
+ + D C + C+NG TC++ Y C C + + DC DV+EC +G
Sbjct: 270 GPDCEVNPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGW---DCSEDVDECETQGPP 324
Query: 242 VCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGG 299
CRNG C+N+ GSF C C G+ G +C + +D+C + C +C + G
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDC--IAATCA--PGSTCIDRVGS 376
Query: 300 YECSCGAGWKLVGRRCVDRDECKELPYVCAG-GECRN--FNGGYVCECPAGWRFDKTAAV 356
+ C C G G C D C P C G +C G +C C G+ +
Sbjct: 377 FSCLCPPG--RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTLCLCQPGY----SGPT 428
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
C + E C A+ Q P C G + C P F +C
Sbjct: 429 CHQDLDE----------CLMAQ--QGPSP---CEHGGS----CLNTP----GSFNCLCPP 465
Query: 417 GMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALD 475
G D +EC +P G C++ +F C CP G +G C V+ +ECA
Sbjct: 466 GYTGSRCEADHNECLSQP-CHPGSTCLDLLATFHCLCPPGL----EGQLCEVETNECASA 520
Query: 476 PRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
P + + C + G++C C PGF+ + D+DEC + +C + G+F C C
Sbjct: 521 PCL-NHADCHDLLNGFQCICLPGFSGTRCEE--DIDECRSSPCANGGQCQDQPGAFHCKC 577
Query: 536 PYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGY--RRTSAPQDSENA 592
G+ +G C+ ++DEC+ +P +C ++ G++ C CP G+ + P + N
Sbjct: 578 LPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNL 633
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS 646
C+ C++Q+D + C+ DGS G P ED C G C RS
Sbjct: 634 CQPKQICKDQKDKAN---CLCPDGS------PGCAPPEDNCTC---HHGHCQRS 675
Score = 167 bits (405), Expect = 2e-40
Identities = 186/634 (29%), Positives = 259/634 (40%), Gaps = 125/634 (19%)
Query: 66 KPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+ ++EC P C GT CH+T FQC C G E C E G P RG +
Sbjct: 193 RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPR----C----ELRAGPCPPRGCS 244
Query: 125 Q---CVNLP---GAFE-CRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRC 176
C +P F C CPPG+ + P +CE + D C + + G C++ + +Y C
Sbjct: 245 NGGTCQLMPEKDSTFHLCLCPPGF-IGP---DCEVNPDNCVSHQCQNGGTCQDGLDTYTC 300
Query: 177 ECKPGYTLRENVCRDVDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVN 234
C +T + DVDEC ++ P CRNG TC+N G++ C C G+ G + +++
Sbjct: 301 LCPETWT-GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW--GGTSCEENLD 357
Query: 235 ECREGGMVCRNGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+C C G C + VGSF C C PG T G C D C L PC D S
Sbjct: 358 DCIAA--TCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMC--LSQPCHGDAQCST 409
Query: 294 TNTNGGYECSCGAGWKLVGRRC-VDRDEC---KELPYVCA-GGECRNFNGGYVCECPAGW 348
G C C G+ G C D DEC ++ P C GG C N G + C CP G+
Sbjct: 410 NPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 467
Query: 349 RFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSA 408
T + C + E C + CH P C + A
Sbjct: 468 ----TGSRCEADHNE-CLSQ----PCH---------PGSTCLDLLA-------------- 495
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCV 467
F +C G+ + +EC P C+ C + F+C C G+ G C
Sbjct: 496 TFHCLCPPGLEGQLCEVETNECASAP--CLNHADCHDLLNGFQCICLPGF----SGTRCE 549
Query: 468 -DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
D DEC P C NG C + G + C+C PGF +GP + +VDEC C
Sbjct: 550 EDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF-EGP-RCQTEVDECLSDPCPVGASCL 605
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRT 583
+ G+F C CP G+ G C ++ C P +C C++ C CP+G
Sbjct: 606 DLPGAFFCLCPSGFT----GQLC-EVPLCA--PNLCQPKQICKDQKDKANCLCPDGSPGC 658
Query: 584 SAPQDS---------ENACE-DIN----ECEEQEDLC------SGGVCINTDGSFLCDCD 623
+ P+D+ ++C D+ ECE + C GG C + C C
Sbjct: 659 APPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 718
Query: 624 AGFEP---SEDGTDCIDRRTGTCYRSLVSGRCEP 654
G+ SE+ T C +G C L G C P
Sbjct: 719 TGYTGPTCSEEMTAC---HSGPC---LNGGSCNP 746
Score = 145 bits (351), Expect = 7e-34
Identities = 153/527 (29%), Positives = 211/527 (40%), Gaps = 105/527 (19%)
Query: 165 GDCRN-TIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCE-------NLPGA-- 213
G C + ++G C+C PG+ L E C+ D C + +C+NG +C+ LP +
Sbjct: 39 GTCLSLSLGQGTCQCAPGF-LGET-CQFPDPCQNAQ-LCQNGGSCQALLPAPLGLPSSPS 95
Query: 214 -----YLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCR-NTVGSFRCECAPGYTLTA 267
+LC C GF G + C + GRC G +C C PG+T
Sbjct: 96 PLTPSFLCTCLPGF-TGERCQAQLEDPCPPS-FCSKRGRCHIQASGRPQCSCMPGWT--- 150
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV-DRDECKELPY 326
G C+ D C +PC G C T +C C G++ G C D +EC + P
Sbjct: 151 -GEQCQLRDFCSA--NPCVNGG--VCLATYPQIQCHCPPGFE--GHACERDVNECFQDPG 203
Query: 327 VCAGG-ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARP 385
C G C N G + C CP G + C E AG C P
Sbjct: 204 PCPKGTSCHNTLGSFQCLCPVG------------QEGPRC--ELRAGPC----------P 239
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN- 444
CS G C+ P DS + +C G P +C V PD CV +C N
Sbjct: 240 PRGCSNGGT----CQLMPEKDSTFHLCLCPPGFIGP-------DCEVNPDNCVSHQCQNG 288
Query: 445 ---TDG--SFRCECPDGYVLAPDGLSCV-DADECALD-PRICGNG-TCSNTRGGYECQCS 496
DG ++ C CP+ + G C D DEC P C NG TC N+ G + C C
Sbjct: 289 GTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
Query: 497 PGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
G+ G ++D+C + C + GSF C CP G G+ C D C+
Sbjct: 345 SGW--GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMCLS 398
Query: 557 EPRVCPHACEN--VVGSYICKCPEGYRRTSAPQDSEN---ACEDINECEEQEDLCSGGVC 611
+P C + GS +C C GY + QD + A + + CE GG C
Sbjct: 399 QPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH------GGSC 452
Query: 612 INTDGSFLCDCDAGFEPSE---DGTDCIDRRT---GTCYRSLVSGRC 652
+NT GSF C C G+ S D +C+ + TC L + C
Sbjct: 453 LNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 499
Score = 96.3 bits (229), Expect = 4e-19
Identities = 119/412 (28%), Positives = 163/412 (39%), Gaps = 91/412 (22%)
Query: 243 CRNG-RCRN-TVGSFRCECAPGYTLTADGRNCRDVDECDE-------------LPHPCGR 287
C NG C + ++G C+CAPG+ G C+ D C LP P G
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFL----GETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 90
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECR-NFNGGYVCECP 345
+PS + + C+C G+ G RC + E P C+ G C +G C C
Sbjct: 91 PSSPSPLTPS--FLCTCLPGF--TGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCE-RCPA 404
GW T C + ++ C A P C + G Y + +C
Sbjct: 147 PGW----TGEQC--QLRDFC----------SANP--------CVNGGVCLATYPQIQCHC 182
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDG 463
P E C+ +D++EC P C G C NT GSF+C CP G +G
Sbjct: 183 PPGFE-GHACE---------RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEG 228
Query: 464 LSC-VDADECALDPRICGN-GTC----SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGR 517
C + A C PR C N GTC + C C PGF GPD V+ D C +
Sbjct: 229 PRCELRAGPC--PPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI-GPDCE-VNPDNCVSHQ 284
Query: 518 ASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDEC-VQEPRVCPH--ACENVVGSYI 573
C + ++ C CP + G C D+DEC Q P C + C+N GS+
Sbjct: 285 CQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
C C G+ TS E++++C G CI+ GSF C C G
Sbjct: 341 CVCVSGWGGTSCE-------ENLDDC-IAATCAPGSTCIDRVGSFSCLCPPG 384
Score = 94.3 bits (224), Expect = 2e-18
Identities = 130/513 (25%), Positives = 177/513 (34%), Gaps = 80/513 (15%)
Query: 380 LQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG 439
L L + C C+ G E C PD + ++CQ G L P
Sbjct: 44 LSLGQGTCQCAPGFLG----ETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 99
Query: 440 GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGN-GTCS-NTRGGYECQCSP 497
SF C C G+ G C E P C G C G +C C P
Sbjct: 100 --------SFLCTCLPGFT----GERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMP 147
Query: 498 GFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQ 556
G+T + C D C+ C T +C CP G+ +G C RD++EC Q
Sbjct: 148 GWT---GEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQ 200
Query: 557 EPRVCPH--ACENVVGSYICKCP---EGYR-RTSAPQDSENACEDINECEEQEDLCSG-G 609
+P CP +C N +GS+ C CP EG R A C + C+ + S
Sbjct: 201 DPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFH 260
Query: 610 VCINTDGSFLCDCDAGFE-----PSEDGTDC---IDRRTGTCYRSLVSGRCEPEXXXXXX 661
+C+ G DC+ + ++G C +D T C + C +
Sbjct: 261 LCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECET 320
Query: 662 XXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWG-SECELCPAPGSPARLDLCTAVNLTPX 720
G C C G WG + CE LD C A P
Sbjct: 321 QGPPHCRNGGTCQNSAGSF---HCVCVSG--WGGTSCE--------ENLDDCIAATCAPG 367
Query: 721 XXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP----GLCAP----GRFRCVCGPGYR 772
L D+ C + P C+ G C+C PGY
Sbjct: 368 STCIDRVGSFSCLCPPGRTGLLCHLEDM--CLSQPCHGDAQCSTNPLTGSTLCLCQPGY- 424
Query: 773 PAGEVC-ADVDECAVR---PPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR-DVDEC 825
+G C D+DEC + P PC+ C NT GS++CLC GY G+ C D +EC
Sbjct: 425 -SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNEC 479
Query: 826 ERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
C + ++ C C G E G C
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLE--GQLC 510
Score = 92.7 bits (220), Expect = 5e-18
Identities = 77/274 (28%), Positives = 109/274 (39%), Gaps = 33/274 (12%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
GTC+ P+G+ C C GY S ++ C G PC C PG + C CPP
Sbjct: 704 GTCYPQPSGYNCTCPTGYTGPTCS---EEMTACHSG--PCLNGGSCNPSPGGYYCTCPPS 758
Query: 141 YRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPR 199
+ + +C+ D C + G C N G++ C C G+ + C S
Sbjct: 759 H----TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGF--QGPRCEGKLRPSCAD 812
Query: 200 PVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCE 258
CRN TC++ P C C G+ G +D+ C + RN C T SF C
Sbjct: 813 SPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDL--CAQRPCP-RNSHCLQTGPSFHCL 869
Query: 259 CAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTN------TNGGYECSCGAGWKLV 311
C G+T G C + C + G D + C N + Y C C G++
Sbjct: 870 CLQGWT----GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ-- 923
Query: 312 GRRCVDR-DECKELPYVCA-GGECRNFNGGYVCE 343
G C D + C+ P C G C GY+C+
Sbjct: 924 GSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQ 955
Score = 71.7 bits (168), Expect = 1e-11
Identities = 108/408 (26%), Positives = 142/408 (34%), Gaps = 80/408 (19%)
Query: 472 CALDPRICGNG-TC-SNTRGGYECQCSPGF----TQGPDQTCVDVDECAEGRASCTFRCH 525
C P C NG TC S + G CQC+PGF Q PD C + C G SC
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNG-GSCQALLP 85
Query: 526 NTAG----------SFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH--ACE-NVVGSY 572
G SF CTC G+ G C+ E P C C G
Sbjct: 86 APLGLPSSPSPLTPSFLCTCLPGFT----GERCQAQLEDPCPPSFCSKRGRCHIQASGRP 141
Query: 573 ICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDG 632
C C G+ T + C N C +GGVC+ T C C GFE G
Sbjct: 142 QCSCMPGW--TGEQCQLRDFC-SANPC------VNGGVCLATYPQIQCHCPPGFE----G 188
Query: 633 TDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAA 692
C +R C++ G C P+ +A C G +
Sbjct: 189 HAC-ERDVNECFQD--PGPC-PKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCS 244
Query: 693 WGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECA 752
G C+L P S L LC + P D + D C
Sbjct: 245 NGGTCQLMPEKDSTFHLCLCPPGFIGP-----------------------DCEVNPDNCV 281
Query: 753 AIP----GLCAPG--RFRCVCGPGYRPAGEVCADVDECAVR-PPPCDQ--LCHNTDGSYD 803
+ G C G + C+C P + DVDEC + PP C C N+ GS+
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLC-PETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340
Query: 804 CLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDG 850
C+C +G+ G +C + +D+C T C + GS+ C C G
Sbjct: 341 CVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG 384
Score = 62.5 bits (145), Expect = 6e-09
Identities = 39/111 (35%), Positives = 53/111 (47%), Gaps = 14/111 (12%)
Query: 747 DVDECAAIP----GLCA--PGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D+DEC + P G C PG F C C PG+ G C +VDEC P P C +
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFE--GPRCQTEVDECLSDPCPVGASCLDLP 608
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
G++ CLC +G+ G C +V C + +QIC + + C C DG
Sbjct: 609 GAFFCLCPSGF----TGQLC-EVPLCAPNLCQPKQICKDQKDKANCLCPDG 654
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 18/117 (15%)
Query: 746 ADVDECAAIPGLCAPGR--------FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCH 796
AD +EC + P C PG F C+C PG G++C + +ECA P CH
Sbjct: 474 ADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE--GQLCEVETNECASAPCLNHADCH 529
Query: 797 NTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+ + C+C G+ G C D+DEC C + G++ C C G+E
Sbjct: 530 DLLNGFQCICLPGFS----GTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE 582
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/113 (31%), Positives = 54/113 (47%), Gaps = 14/113 (12%)
Query: 747 DVDECAAIPGL----CAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+ +ECA+ P L C F+C+C PG+ +G C D+DEC P C +
Sbjct: 513 ETNECASAPCLNHADCHDLLNGFQCICLPGF--SGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G++ C C G+E G C+ +VDEC D C + G++ C C G+
Sbjct: 571 GAFHCKCLPGFE----GPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGF 619
Score = 48.4 bits (110), Expect = 1e-04
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 8/97 (8%)
Query: 757 LCAPGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 815
L PG F C+C PGY G C AD +EC +P C + ++ CLC G E
Sbjct: 453 LNTPGSFNCLCPPGY--TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE---- 506
Query: 816 GANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C + +EC C + ++C C G+
Sbjct: 507 GQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 543
Score = 42.3 bits (95), Expect = 0.007
Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 10/101 (9%)
Query: 749 DECAAIPGLCAPGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCR 807
D C G C R CVC G+ G C A++ C P C+ Y+C C
Sbjct: 663 DNCTCHHGHCQ--RSSCVCDVGW--TGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 718
Query: 808 TGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSC 847
TGY G C ++ C C+ + G Y C+C
Sbjct: 719 TGY----TGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 755
Score = 41.1 bits (92), Expect = 0.016
Identities = 31/106 (29%), Positives = 45/106 (42%), Gaps = 18/106 (16%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DV 822
RC+C GY G +D CA RP P + C T S+ CLC G+ G C +
Sbjct: 829 RCLCPTGYT-GGSCQTLMDLCAQRPCPRNSHCLQTGPSFHCLCLQGW----TGPLCNLPL 883
Query: 823 DECERD--------THTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
C++ + C +C ++ SY C C G++ G C
Sbjct: 884 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLC 927
Score = 40.3 bits (90), Expect = 0.028
Identities = 26/101 (25%), Positives = 37/101 (36%), Gaps = 7/101 (6%)
Query: 759 APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
+PG + C C P + G C D C P C N G++ CLC G++
Sbjct: 747 SPGGYYCTCPPSH--TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEG 804
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
R C + C ++ C C GY G +C
Sbjct: 805 KLR--PSCADSPCRNRATCQDSPQGPRCLCPTGY--TGGSC 841
>AK074499-1|BAC11024.1| 636|Homo sapiens protein ( Homo sapiens
cDNA FLJ90018 fis, clone HEMBA1000732, highly similar to
Homo sapiens mRNA for latent transforming growth
factor-beta ).
Length = 636
Score = 192 bits (469), Expect = 3e-48
Identities = 119/347 (34%), Positives = 159/347 (45%), Gaps = 24/347 (6%)
Query: 181 GYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREG 239
G LR DVDECS +C++G C N G++ C C G +AGP+ C+DV+ECRE
Sbjct: 8 GPGLRTPCPADVDECSE-EDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRER 66
Query: 240 G-MVCRNGRCRNTVGSFRC--ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
G +CR+ RC N+ GS+RC +C PGY +G C DV+EC+ L CG C N
Sbjct: 67 GPALCRSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVNECETLQGVCGA---ALCENV 122
Query: 297 NGGYECSCGAGWK----LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDK 352
G + C C + + GR R P P R
Sbjct: 123 EGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPST 182
Query: 353 TAAVCVDERKELCYDEWEA-GRCHRARPLQLARPECCCSEGAAWGRYC--ERCPAPDSAE 409
V + CY + A C + ECCC+ G WG C ++CP ++AE
Sbjct: 183 PRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAE 242
Query: 410 FMRICQGGMG--RPN----LTQDLDECRV-RPDVCVGGRCVNTDGSFRCECPDGYVLAPD 462
+ +C G G P+ L +D+DEC++ R VC G CVNT + C C +GY
Sbjct: 243 YQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQ 302
Query: 463 GLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCV 508
L C+D DECA + C G C NT G Y C C P G + CV
Sbjct: 303 RLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCV 349
Score = 140 bits (339), Expect = 2e-32
Identities = 112/325 (34%), Positives = 143/325 (44%), Gaps = 28/325 (8%)
Query: 232 DVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNP 291
DV+EC E + C++G C NT GSF C C PG+ D +C DVDEC E R +
Sbjct: 18 DVDECSEEDL-CQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCR--SQ 74
Query: 292 SCTNTNGGYEC--SCGAGWKLVGR-RCVDRDECKELPYVCAGGECRNFNGGYVCECP-AG 347
C N+ G Y C C G+ C D +EC+ L VC C N G ++C CP +
Sbjct: 75 RCENSPGSYRCVRDCDPGYHAGPEGTCDDVNECETLQGVCGAALCENVEGSFLCVCPNSP 134
Query: 348 WRFDKTAAVCVDERKEL-----CYDEWEAGRCHRARPLQ--LARPECCCSEGAAWGRYCE 400
FD CV R + A ARP L R +G G
Sbjct: 135 EEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPV-GSGRR 193
Query: 401 RCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR---CVNTD-GSFRCECPDG 456
C +A C + R N+T C V G R C T+ ++ CP G
Sbjct: 194 ECYFDTAAP--DACDNILAR-NVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHG 250
Query: 457 Y-VLAPDG-LSCV-DADECAL-DPRICGNGTCSNTRGGYECQCSPGFTQGPDQT-CVDVD 511
LAP G LS D DEC L ++C +G C NT GY C CS G+ + C+D D
Sbjct: 251 RGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDND 310
Query: 512 ECAEGRASCT-FRCHNTAGSFRCTC 535
ECA+ +C RC NT GS+ CTC
Sbjct: 311 ECADEEPACEGGRCVNTVGSYHCTC 335
Score = 122 bits (294), Expect = 5e-27
Identities = 114/370 (30%), Positives = 147/370 (39%), Gaps = 57/370 (15%)
Query: 468 DADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAE-GRASC-TFRC 524
D DEC+ + +C +G C+NT G +EC C PG GPD +C+DVDEC E G A C + RC
Sbjct: 18 DVDECS-EEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCRSQRC 76
Query: 525 HNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRR 582
N+ GS+RC C GY +G C D++EC VC G+ +C+ EG
Sbjct: 77 ENSPGSYRCVRDCDPGYHAGPEGT-CDDVNECETLQGVC--------GAALCENVEGSFL 127
Query: 583 TSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGT 642
P E C S G GS + P+ + RR T
Sbjct: 128 CVCPNSPEEFDPMTGRCVPPRT--SAGTF---PGSQPQAPASPVLPARPPPPPLPRRPST 182
Query: 643 CYRSLV-SGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCP 701
+ V SGR E +VT +CCCT+G WGS C +
Sbjct: 183 PRQGPVGSGRRE--------CYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQ 234
Query: 702 APGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAI------P 755
PG+ + +L P L + DVDEC
Sbjct: 235 CPGT----ETAEYQSLCPHGRGYLAPSGD-----------LSLRRDVDECQLFRDQVCKS 279
Query: 756 GLC---APGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTG 809
G+C APG + C C GY + C D DECA P C+ C NT GSY C C
Sbjct: 280 GVCVNTAPG-YSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPP 338
Query: 810 YELDEDGANC 819
LD C
Sbjct: 339 LVLDGSQRRC 348
Score = 117 bits (282), Expect = 2e-25
Identities = 57/126 (45%), Positives = 68/126 (53%), Gaps = 6/126 (4%)
Query: 416 GGMG-RPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC-A 473
GG G R D+DEC D+C G C NTDGSF C CP G+ PD SC+D DEC
Sbjct: 7 GGPGLRTPCPADVDECS-EEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRE 65
Query: 474 LDPRICGNGTCSNTRGGYEC--QCSPGFTQGPDQTCVDVDECAEGRASC-TFRCHNTAGS 530
P +C + C N+ G Y C C PG+ GP+ TC DV+EC + C C N GS
Sbjct: 66 RGPALCRSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVNECETLQGVCGAALCENVEGS 125
Query: 531 FRCTCP 536
F C CP
Sbjct: 126 FLCVCP 131
Score = 114 bits (274), Expect = 1e-24
Identities = 53/113 (46%), Positives = 64/113 (56%), Gaps = 5/113 (4%)
Query: 152 DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRP-VCRNGTCE 208
DVDEC ++ +C G C NT GS+ C C PG+ ++ C DVDEC P +CR+ CE
Sbjct: 18 DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCRSQRCE 77
Query: 209 NLPGAYLC--HCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCEC 259
N PG+Y C CD G+ AGP C DVNEC VC C N GSF C C
Sbjct: 78 NSPGSYRCVRDCDPGYHAGPEGTCDDVNECETLQGVCGAALCENVEGSFLCVC 130
Score = 105 bits (253), Expect = 5e-22
Identities = 53/115 (46%), Positives = 66/115 (57%), Gaps = 7/115 (6%)
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQ--RICDHGD 166
DVDECS C+ C N G+FEC CPPG+R P L C DVDEC ++ +C
Sbjct: 18 DVDECS-EEDLCQS-GICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCRSQR 75
Query: 167 CRNTIGSYRC--ECKPGYTL-RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHC 218
C N+ GSYRC +C PGY E C DV+EC + VC CEN+ G++LC C
Sbjct: 76 CENSPGSYRCVRDCDPGYHAGPEGTCDDVNECETLQGVCGAALCENVEGSFLCVC 130
Score = 95.5 bits (227), Expect = 7e-19
Identities = 47/133 (35%), Positives = 68/133 (51%), Gaps = 7/133 (5%)
Query: 23 CCCSVGHAWGAPC--EACPPRGSPAHTALCGEKPGEYINPVTNET--KPIDECDIM-PQL 77
CCC+VG WG+ C + CP + + +LC G Y+ P + + + +DEC + Q+
Sbjct: 218 CCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRG-YLAPSGDLSLRRDVDECQLFRDQV 276
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRC 137
CK G C +T G+ C C +GY + C D DEC+ P C G +CVN G++ C C
Sbjct: 277 CKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEG-GRCVNTVGSYHCTC 335
Query: 138 PPGYRLTPSLDEC 150
P L S C
Sbjct: 336 EPPLVLDGSQRRC 348
Score = 93.1 bits (221), Expect = 4e-18
Identities = 63/186 (33%), Positives = 77/186 (41%), Gaps = 17/186 (9%)
Query: 240 GMVCRNGRCRNT-VGSFRCECAPGYTLTADGRNC---RDVDECDELPHPCGRDGNPSCTN 295
G CR +C T ++ C G A + RDVDEC + G C N
Sbjct: 227 GSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSG--VCVN 284
Query: 296 TNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKT 353
T GY C C G+ +R C+D DEC + C GG C N G Y C C D +
Sbjct: 285 TAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGS 344
Query: 354 AAVCV-------DERKELCYDEWEAGR-C-HRARPLQLARPECCCSEGAAWGRYCERCPA 404
CV D+ +C+ E A C H Q ECCC G AWG C CPA
Sbjct: 345 QRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPA 404
Query: 405 PDSAEF 410
DS +F
Sbjct: 405 QDSDDF 410
Score = 91.5 bits (217), Expect = 1e-17
Identities = 115/416 (27%), Positives = 150/416 (36%), Gaps = 53/416 (12%)
Query: 317 DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVC--VDE---------RKELC 365
D DEC E +C G C N +G + C CP G R A C VDE R + C
Sbjct: 18 DVDECSEED-LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCRSQRC 76
Query: 366 YDEWEAGRCHR-ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM--GRPN 422
+ + RC R P A PE C + CE A +G PN
Sbjct: 77 ENSPGSYRCVRDCDPGYHAGPEGTCDDV----NECETLQGVCGAALCENVEGSFLCVCPN 132
Query: 423 LTQDLDECRVRPDVCVGGRC-VNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGN 481
++ D R CV R T + + P VL P PR
Sbjct: 133 SPEEFDPMTGR---CVPPRTSAGTFPGSQPQAPASPVL-PARPPPPPLPRRPSTPRQGPV 188
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECA----EGRAS-CTFR-CHNT-AGSFRCT 534
G S R Y +P V EC EG S C + C T ++
Sbjct: 189 G--SGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSL 246
Query: 535 CPYG---YAVAADGVHCRDIDEC-VQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDS 589
CP+G A + D RD+DEC + +VC C N Y C C GY + +
Sbjct: 247 CPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLE- 305
Query: 590 ENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVS 649
C D +EC ++E C GG C+NT GS+ C C+ C+ + + +L
Sbjct: 306 ---CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL-- 360
Query: 650 GRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSECELCPAPGS 705
G C E T +CCC G AWG +C LCPA S
Sbjct: 361 GVCWQEVGADLVCSHPRLDR---------QATYTECCCLYGEAWGMDCALCPAQDS 407
Score = 86.2 bits (204), Expect = 4e-16
Identities = 50/121 (41%), Positives = 64/121 (52%), Gaps = 14/121 (11%)
Query: 746 ADVDECA----AIPGLCA--PGRFRCVCGPGYRPAGEV--CADVDECAVRPPP-C-DQLC 795
ADVDEC+ G+C G F C+C PG+R ++ C DVDEC R P C Q C
Sbjct: 17 ADVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCRSQRC 76
Query: 796 HNTDGSYDCL--CRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYE 852
N+ GSY C+ C GY +G C DV+ECE C +C N EGS+ C C + E
Sbjct: 77 ENSPGSYRCVRDCDPGYHAGPEG-TCDDVNECETLQGVCGAALCENVEGSFLCVCPNSPE 135
Query: 853 K 853
+
Sbjct: 136 E 136
Score = 80.6 bits (190), Expect = 2e-14
Identities = 42/114 (36%), Positives = 54/114 (47%), Gaps = 5/114 (4%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+DEC LC+ G C +T F+C C G+ C DVDEC P +C
Sbjct: 19 VDECS-EEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCRSQRCE 77
Query: 128 NLPGAFEC--RCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRNTIGSYRCEC 178
N PG++ C C PGY P C+DV+EC Q +C C N GS+ C C
Sbjct: 78 NSPGSYRCVRDCDPGYHAGPE-GTCDDVNECETLQGVCGAALCENVEGSFLCVC 130
Score = 79.8 bits (188), Expect = 4e-14
Identities = 47/143 (32%), Positives = 64/143 (44%), Gaps = 15/143 (10%)
Query: 134 ECRCP--PGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRD 191
EC C G+ + +C + Q +C HG R P L ++ RD
Sbjct: 217 ECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHG---------RGYLAPSGDL--SLRRD 265
Query: 192 VDECSRPRP-VCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCR 249
VDEC R VC++G C N Y C+C +G+ +C+D +EC + C GRC
Sbjct: 266 VDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCV 325
Query: 250 NTVGSFRCECAPGYTLTADGRNC 272
NTVGS+ C C P L R C
Sbjct: 326 NTVGSYHCTCEPPLVLDGSQRRC 348
Score = 75.8 bits (178), Expect = 6e-13
Identities = 40/88 (45%), Positives = 50/88 (56%), Gaps = 6/88 (6%)
Query: 768 GPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC-E 826
GPG R ADVDEC+ +C NTDGS++C+C G+ D A+C DVDEC E
Sbjct: 8 GPGLRTPCP--ADVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRE 65
Query: 827 RDTHTCQ-QICSNTEGSYEC--SCEDGY 851
R C+ Q C N+ GSY C C+ GY
Sbjct: 66 RGPALCRSQRCENSPGSYRCVRDCDPGY 93
Score = 74.9 bits (176), Expect = 1e-12
Identities = 43/112 (38%), Positives = 51/112 (45%), Gaps = 5/112 (4%)
Query: 78 CKPGTCHDTPTG-FQCGCDHGYEHDNTS---HLCRDVDECSWGRPPCRGMAQCVNLPGAF 133
C+ C T T +Q C HG + S L RDVDEC R CVN +
Sbjct: 230 CRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGY 289
Query: 134 ECRCPPGYRLTPSLDECEDVDECGDQR-ICDHGDCRNTIGSYRCECKPGYTL 184
C C GY EC D DEC D+ C+ G C NT+GSY C C+P L
Sbjct: 290 SCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVL 341
Score = 72.1 bits (169), Expect = 8e-12
Identities = 32/75 (42%), Positives = 40/75 (53%), Gaps = 4/75 (5%)
Query: 202 CRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREG---GMVCRNGRCRNTVGSFRC 257
C NG C +P + C C DG++ CVD+NEC E +C N RC NT GSFRC
Sbjct: 555 CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC 614
Query: 258 ECAPGYTLTADGRNC 272
C PG+ T +C
Sbjct: 615 ICRPGFAPTHQPHHC 629
Score = 70.9 bits (166), Expect = 2e-11
Identities = 35/88 (39%), Positives = 44/88 (50%), Gaps = 6/88 (6%)
Query: 416 GGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC--- 472
G + P + +EC + D C GRCV F C C DGY L ++CVD +EC
Sbjct: 535 GSLAEPYEELEAEECGIL-DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEA 593
Query: 473 -ALDPRICGNGTCSNTRGGYECQCSPGF 499
A P +C N C NT G + C C PGF
Sbjct: 594 EAASP-LCVNARCLNTDGSFRCICRPGF 620
Score = 63.3 bits (147), Expect = 4e-09
Identities = 36/90 (40%), Positives = 44/90 (48%), Gaps = 6/90 (6%)
Query: 765 CVCGPGY-RPAGEVCA--DVDECAV-RPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANC 819
C G GY P+G++ DVDEC + R C +C NT Y C C GY C
Sbjct: 247 CPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLEC 306
Query: 820 RDVDECERDTHTCQ-QICSNTEGSYECSCE 848
D DEC + C+ C NT GSY C+CE
Sbjct: 307 IDNDECADEEPACEGGRCVNTVGSYHCTCE 336
Score = 62.9 bits (146), Expect = 5e-09
Identities = 32/78 (41%), Positives = 39/78 (50%), Gaps = 7/78 (8%)
Query: 565 CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQE---DLCSGGVCINTDGSFLCD 621
C V + C+C +GYR + AC DINEC+E E LC C+NTDGSF C
Sbjct: 560 CVRVPEGFTCRCFDGYRLDM----TRMACVDINECDEAEAASPLCVNARCLNTDGSFRCI 615
Query: 622 CDAGFEPSEDGTDCIDRR 639
C GF P+ C R
Sbjct: 616 CRPGFAPTHQPHHCAPAR 633
Score = 62.1 bits (144), Expect = 8e-09
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 6/87 (6%)
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCTF--- 522
++A+EC + C NG C G+ C+C G+ + CVD++EC E A+
Sbjct: 544 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 602
Query: 523 -RCHNTAGSFRCTCPYGYAVAADGVHC 548
RC NT GSFRC C G+A HC
Sbjct: 603 ARCLNTDGSFRCICRPGFAPTHQPHHC 629
Score = 62.1 bits (144), Expect = 8e-09
Identities = 26/62 (41%), Positives = 37/62 (59%), Gaps = 4/62 (6%)
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQR----ICDHGDCRNTIGSYRCECKP 180
+CV +P F CRC GYRL + C D++EC + +C + C NT GS+RC C+P
Sbjct: 559 RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRP 618
Query: 181 GY 182
G+
Sbjct: 619 GF 620
Score = 61.3 bits (142), Expect = 1e-08
Identities = 31/84 (36%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDEC--SWGRPPCRGMAQC 126
+EC I+ C G C P GF C C GY D T C D++EC + P A+C
Sbjct: 547 EECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARC 605
Query: 127 VNLPGAFECRCPPGYRLTPSLDEC 150
+N G+F C C PG+ T C
Sbjct: 606 LNTDGSFRCICRPGFAPTHQPHHC 629
Score = 59.3 bits (137), Expect = 6e-08
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 5/88 (5%)
Query: 54 PGEYINPVTNETKPIDEC-DIMPQLCKPGTCHDTPTGFQC--GCDHGYEHDNTSHLCRDV 110
PG P +DEC + P LC+ C ++P ++C CD GY H C DV
Sbjct: 46 PGHRAGPDLASCLDVDECRERGPALCRSQRCENSPGSYRCVRDCDPGY-HAGPEGTCDDV 104
Query: 111 DECSWGRPPCRGMAQCVNLPGAFECRCP 138
+EC + C G A C N+ G+F C CP
Sbjct: 105 NECETLQGVC-GAALCENVEGSFLCVCP 131
Score = 59.3 bits (137), Expect = 6e-08
Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Query: 219 DDGFKAGPNNDCVDVNECREGGMV--CRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVD 276
+ G AG + + E E G++ C NGRC F C C GY L C D++
Sbjct: 529 EGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDIN 588
Query: 277 ECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
ECDE N C NT+G + C C G+
Sbjct: 589 ECDEAEAASPLCVNARCLNTDGSFRCICRPGF 620
Score = 51.6 bits (118), Expect = 1e-05
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 5/76 (6%)
Query: 152 DVDECGDQRICDHGDCRNTIGSYRCECKPGYTL--RENVCRDVDECSRPR---PVCRNGT 206
+ +ECG C +G C + C C GY L C D++EC P+C N
Sbjct: 545 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 604
Query: 207 CENLPGAYLCHCDDGF 222
C N G++ C C GF
Sbjct: 605 CLNTDGSFRCICRPGF 620
Score = 47.6 bits (108), Expect = 2e-04
Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 14/86 (16%)
Query: 747 DVDECAAIPGLCAPGR-------FRCVCGPGYR--PAGEVCADVDEC----AVRPPPCDQ 793
+ +EC + G C GR F C C GYR C D++EC A P +
Sbjct: 545 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 603
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANC 819
C NTDGS+ C+CR G+ +C
Sbjct: 604 RCLNTDGSFRCICRPGFAPTHQPHHC 629
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 4/76 (5%)
Query: 780 DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC---ERDTHTCQQI- 835
+ +EC + + C + C C GY LD C D++EC E + C
Sbjct: 545 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 604
Query: 836 CSNTEGSYECSCEDGY 851
C NT+GS+ C C G+
Sbjct: 605 CLNTDGSFRCICRPGF 620
Score = 45.2 bits (102), Expect = 0.001
Identities = 29/91 (31%), Positives = 37/91 (40%), Gaps = 3/91 (3%)
Query: 381 QLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ--DLDECRVRPDVCV 438
+L EC +G GR C R P + + M R + DE +CV
Sbjct: 543 ELEAEECGILDGCTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 601
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
RC+NTDGSFRC C G+ C A
Sbjct: 602 NARCLNTDGSFRCICRPGFAPTHQPHHCAPA 632
Score = 42.7 bits (96), Expect = 0.005
Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 10/102 (9%)
Query: 489 GGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC 548
G Y + + + + C +D C GR C F C C GY + + C
Sbjct: 531 GSYAGSLAEPYEELEAEECGILDGCTNGR------CVRVPEGFTCRCFDGYRLDMTRMAC 584
Query: 549 RDIDECVQEPR---VCPHA-CENVVGSYICKCPEGYRRTSAP 586
DI+EC + +C +A C N GS+ C C G+ T P
Sbjct: 585 VDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQP 626
Score = 40.3 bits (90), Expect = 0.028
Identities = 16/36 (44%), Positives = 21/36 (58%)
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
DVDEC + IC+NT+GS+EC C G+ D
Sbjct: 18 DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPD 53
Score = 39.1 bits (87), Expect = 0.066
Identities = 29/82 (35%), Positives = 35/82 (42%), Gaps = 7/82 (8%)
Query: 316 VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGR-- 373
++ +EC L C G C G+ C C G+R D T CVD + C DE EA
Sbjct: 544 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINE--C-DEAEAASPL 599
Query: 374 CHRARPLQL-ARPECCCSEGAA 394
C AR L C C G A
Sbjct: 600 CVNARCLNTDGSFRCICRPGFA 621
Score = 37.5 bits (83), Expect = 0.20
Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 6/65 (9%)
Query: 793 QLCHNTD-GSYDCLCR--TGYELDEDGANCR-DVDECE--RDTHTCQQICSNTEGSYECS 846
Q C T+ Y LC GY + R DVDEC+ RD +C NT Y C
Sbjct: 233 QQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY 292
Query: 847 CEDGY 851
C +GY
Sbjct: 293 CSNGY 297
Score = 35.5 bits (78), Expect = 0.81
Identities = 13/27 (48%), Positives = 14/27 (51%)
Query: 23 CCCSVGHAWGAPCEACPPRGSPAHTAL 49
CCC G AWG C CP + S AL
Sbjct: 387 CCCLYGEAWGMDCALCPAQDSDDFEAL 413
>Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein.
Length = 1223
Score = 190 bits (463), Expect = 2e-47
Identities = 176/631 (27%), Positives = 255/631 (40%), Gaps = 85/631 (13%)
Query: 23 CCCSVGHAW-GAPCEACPPRGSPAHTALCGEKPGEYINPVTNE-----TKPIDECDIMPQ 76
C CS G W G C+ C P H + C E P + N TN K ++ C
Sbjct: 246 CRCSYG--WQGRFCDECVPYPGCVHGS-CVE-PWQ-CNCETNWGGLLCDKDLNYCGSHHP 300
Query: 77 LCKPGTCHDT-PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC 135
GTC + P ++C C GY N C + P C C +P FEC
Sbjct: 301 CTNGGTCINAEPDQYRCTCPDGYSGRN----CEKAEHACTSNP-CANGGSCHEVPSGFEC 355
Query: 136 RCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDEC 195
CP G+ P+ D+DEC G C + + + C C P + D +EC
Sbjct: 356 HCPSGWS-GPTCASA-DIDECASNPCAAGGTCVDQVDGFECIC-PEQWVGATCQLDANEC 412
Query: 196 SRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSF 255
+P +C+NL G Y C C G+K N ++VN+CR G G C++ V +
Sbjct: 413 EG-KPCLNAFSCKNLIGGYYCDCIPGWKG--INCHINVNDCR--GQCQHGGTCKDLVNGY 467
Query: 256 RCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR 314
+C C G+ GR+C + DEC PC G C + G+ C C G+ G
Sbjct: 468 QCVCPRGF----GGRHCELERDECAS--SPCHSGG--LCEDLADGFHCHCPQGFS--GPL 517
Query: 315 C-VDRDECKELPYVCAGG-ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAG 372
C VD D C+ P C G C N G Y C CP + K +V +E C G
Sbjct: 518 CEVDVDLCEPSP--CRNGARCYNLEGDYYCACPDDFG-GKNCSV----PREPC----PGG 566
Query: 373 RCHRARPLQLARPECCCS-EGAAWGRYCE---RCPAPDSAEFMRICQGGMGRPNLTQDLD 428
C R + + G A C RC + F IC G +++D
Sbjct: 567 AC---RVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENID 623
Query: 429 ECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRIC-GNGTCS 485
+C +P C GG C++ +FRC CP G+ +G C + ++C DP C G C
Sbjct: 624 DCLGQP--CRNGGTCIDEVDAFRCFCPSGW----EGELCDTNPNDCLPDP--CHSRGRCY 675
Query: 486 NTRGGYECQCSPGFTQGPDQTCVDVD-ECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
+ + C C G+ +TC + +C S C+++ +FRC CP G+ +
Sbjct: 676 DLVNDFYCACDDGWK---GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTC 732
Query: 545 GVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED 604
V C+ P V C S+ C C +G+ + + N+C
Sbjct: 733 AVAKNS--SCLPNPCVNGGTCVGSGASFSCICRDGW-------EGRTCTHNTNDCNPLP- 782
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
+GG+C++ F C+C GF G DC
Sbjct: 783 CYNGGICVDGVNWFRCECAPGFA----GPDC 809
Score = 180 bits (438), Expect = 2e-44
Identities = 187/625 (29%), Positives = 261/625 (41%), Gaps = 111/625 (17%)
Query: 20 KYLCCCSVGHAWGAPCE----ACPPR----GSPAHTALCGEK---PGEYINPVTNETKPI 68
+Y C C G++ G CE AC G H G + P + P T + I
Sbjct: 314 QYRCTCPDGYS-GRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGP-TCASADI 371
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC P GTC D GF+C C + T L D +EC G+P C C N
Sbjct: 372 DECASNP-CAAGGTCVDQVDGFECICPEQWV-GATCQL--DANECE-GKP-CLNAFSCKN 425
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD-CRNTIGSYRCECKPGYTLREN 187
L G + C C PG++ ++ +V++C Q C HG C++ + Y+C C G+ R
Sbjct: 426 LIGGYYCDCIPGWK---GINCHINVNDCRGQ--CQHGGTCKDLVNGYQCVCPRGFGGRH- 479
Query: 188 VCR-DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
C + DEC+ P G CE+L + CHC GF +GP + VDV+ C CRNG
Sbjct: 480 -CELERDECASS-PCHSGGLCEDLADGFHCHCPQGF-SGPLCE-VDVDLCEPSP--CRNG 533
Query: 247 -RCRNTVGSFRCECAPGY--------TLTADGRNCRDVDECDELPHP----------CGR 287
RC N G + C C + G CR +D C P CG
Sbjct: 534 ARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGP 593
Query: 288 DGNPSCTNTNGG-YECSCGAGWKLVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCEC 344
G C + GG + C C +G+ G C + D+C P C GG C + + C C
Sbjct: 594 HGR--CVSQPGGNFSCICDSGF--TGTYCHENIDDCLGQP--CRNGGTCIDEVDAFRCFC 647
Query: 345 PAGWRFDKTAAVCVDERKELCYDEWEAGRCH-RARPLQLARP-ECCCSEGAAW-GRYCE- 400
P+GW + +C D C + CH R R L C C +G W G+ C
Sbjct: 648 PSGWEGE----LC-DTNPNDCLPD----PCHSRGRCYDLVNDFYCACDDG--WKGKTCHS 696
Query: 401 ---RCPAP---------DSAEFMRIC--QGGMGRPNLTQDLDECRVRPDVCV-GGRCVNT 445
+C A DS + R G G C P+ CV GG CV +
Sbjct: 697 REFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCL--PNPCVNGGTCVGS 754
Query: 446 DGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGP 503
SF C C DG+ +G +C + ++C +P C NG C + + C+C+PGF GP
Sbjct: 755 GASFSCICRDGW----EGRTCTHNTNDC--NPLPCYNGGICVDGVNWFRCECAPGFA-GP 807
Query: 504 DQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI----DECVQEPR 559
D +++DEC + C + +RC+CP G A G C+++ C
Sbjct: 808 DCR-INIDECQSSPCAYGATCVDEINGYRCSCPPGRA----GPRCQEVIGFGRSCWSRGT 862
Query: 560 VCPHACENVVGSYICKCPEGYRRTS 584
PH V C+C +G R S
Sbjct: 863 PFPHGSSWVEDCNSCRCLDGRRDCS 887
Score = 157 bits (382), Expect = 1e-37
Identities = 155/562 (27%), Positives = 225/562 (40%), Gaps = 100/562 (17%)
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDE----CE-DVDECGDQRICDHGD- 166
CS+G R +CV PG C ++ + C+ D++ CG C +G
Sbjct: 248 CSYGWQG-RFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGT 306
Query: 167 CRNTI-GSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG 225
C N YRC C GY+ R C + P G+C +P + CHC G+ +G
Sbjct: 307 CINAEPDQYRCTCPDGYSGRN--CEKAEHACTSNPCANGGSCHEVPSGFECHCPSGW-SG 363
Query: 226 PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHP 284
P D++EC G C + V F C C + G C+ D +EC+ P
Sbjct: 364 PTCASADIDECASNPCAA-GGTCVDQVDGFECICPEQWV----GATCQLDANECE--GKP 416
Query: 285 CGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCE 343
C SC N GGY C C GWK G C ++ ++C+ GG C++ GY C
Sbjct: 417 CLNAF--SCKNLIGGYYCDCIPGWK--GINCHINVNDCR--GQCQHGGTCKDLVNGYQCV 470
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
CP G+ C ER DE + CH C E A G +C CP
Sbjct: 471 CPRGF----GGRHCELER-----DECASSPCHSG--------GLC--EDLADGFHC-HCP 510
Query: 404 APDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGY----V 458
QG G P D+D C P C G RC N +G + C CPD +
Sbjct: 511 -----------QGFSG-PLCEVDVDLC--EPSPCRNGARCYNLEGDYYCACPDDFGGKNC 556
Query: 459 LAP----DGLSCVDADECALD----------PRICG-NGTCSNTRGG-YECQCSPGFTQG 502
P G +C D C D +CG +G C + GG + C C GFT
Sbjct: 557 SVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFT-- 614
Query: 503 PDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVC 561
++D+C C + +FRC CP G+ +G C + ++C+ +P
Sbjct: 615 GTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGW----EGELCDTNPNDCLPDPCHS 670
Query: 562 PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCD 621
C ++V + C C +G++ + E C D C +GG C ++ +F C
Sbjct: 671 RGRCYDLVNDFYCACDDGWKGKTC-HSREFQC-DAYTCS------NGGTCYDSGDTFRCA 722
Query: 622 CDAGFEPSEDGTDCIDRRTGTC 643
C G++ G+ C + +C
Sbjct: 723 CPPGWK----GSTCAVAKNSSC 740
Score = 118 bits (285), Expect = 7e-26
Identities = 135/492 (27%), Positives = 191/492 (38%), Gaps = 85/492 (17%)
Query: 201 VCRNGTCENLPGAYL----CHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFR 256
VC+ G C L G C C G++ ++CV C G C V ++
Sbjct: 228 VCKQG-CNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGS-------C---VEPWQ 276
Query: 257 CECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGG-YECSCGAGWKLVGRR 314
C C + G C +D++ C HPC G +C N Y C+C G+ GR
Sbjct: 277 CNCETNW----GGLLCDKDLNYCGS-HHPCTNGG--TCINAEPDQYRCTCPDGYS--GRN 327
Query: 315 CVDRDE-CKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKE-------LC 365
C + C P CA GG C G+ C CP+GW A+ +DE C
Sbjct: 328 CEKAEHACTSNP--CANGGSCHEVPSGFECHCPSGWSGPTCASADIDECASNPCAAGGTC 385
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS--AEFMRICQGGMGRPNL 423
D+ + C P Q C G+ C + + + C G N
Sbjct: 386 VDQVDGFEC--ICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINC 443
Query: 424 TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNG 482
++++CR + GG C + ++C CP G+ G C ++ DECA P G G
Sbjct: 444 HINVNDCRGQCQ--HGGTCKDLVNGYQCVCPRGF----GGRHCELERDECASSPCHSG-G 496
Query: 483 TCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA- 540
C + G+ C C GF+ GP C VDVD C RC+N G + C CP +
Sbjct: 497 LCEDLADGFHCHCPQGFS-GP--LCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGG 553
Query: 541 -------VAADGVHCRDIDECVQE----------PRVC-PHA-C-ENVVGSYICKCPEGY 580
G CR ID C + VC PH C G++ C C G+
Sbjct: 554 KNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGF 613
Query: 581 RRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRT 640
T E+I++C Q +GG CI+ +F C C +G+E T+ D
Sbjct: 614 TGTYCH-------ENIDDCLGQ-PCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLP 665
Query: 641 GTCYRSLVSGRC 652
C+ GRC
Sbjct: 666 DPCHS---RGRC 674
Score = 109 bits (261), Expect = 5e-23
Identities = 97/342 (28%), Positives = 144/342 (42%), Gaps = 49/342 (14%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
ID+C + Q C+ G TC D F+C C G+E + LC D + PC +C
Sbjct: 622 IDDC--LGQPCRNGGTCIDEVDAFRCFCPSGWEGE----LC-DTNPNDCLPDPCHSRGRC 674
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD-CRNTIGSYRCECKPGYTLR 185
+L F C C G++ C + D C +G C ++ ++RC C PG+ +
Sbjct: 675 YDLVNDFYCACDDGWKGKT----CHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGW--K 728
Query: 186 ENVCRDVDECS-RPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCV-DVNECREGGMVC 243
+ C S P P GTC ++ C C DG++ C + N+C + C
Sbjct: 729 GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEG---RTCTHNTNDCNP--LPC 783
Query: 244 RNGR-CRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYE 301
NG C + V FRCECAPG+ G +CR ++DEC P G +C + GY
Sbjct: 784 YNGGICVDGVNWFRCECAPGFA----GPDCRINIDECQSSPCAYG----ATCVDEINGYR 835
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER 361
CSC G G RC + + G C ++ G + W D + C+D R
Sbjct: 836 CSCPPG--RAGPRCQE--------VIGFGRSC--WSRGTPFPHGSSWVEDCNSCRCLDGR 883
Query: 362 KELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
++ C W C L +PE ++ R E+ P
Sbjct: 884 RD-CSKVW----CGWKPCLLAGQPEALSAQCPLGQRCLEKAP 920
Score = 53.2 bits (122), Expect = 4e-06
Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 5/94 (5%)
Query: 760 PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
P F C C G+ AD+DECA P C + ++C+C + GA C
Sbjct: 350 PSGFECHCPSGWSGPTCASADIDECASNPCAAGGTCVDQVDGFECICPEQWV----GATC 405
Query: 820 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+ D +ECE C N G Y C C G++
Sbjct: 406 QLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWK 439
Score = 50.4 bits (115), Expect = 3e-05
Identities = 38/119 (31%), Positives = 52/119 (43%), Gaps = 19/119 (15%)
Query: 746 ADVDECAAIP----GLCAP--GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNT 798
AD+DECA+ P G C F C+C + G C D +EC +P C N
Sbjct: 369 ADIDECASNPCAAGGTCVDQVDGFECICPEQW--VGATCQLDANECEGKPCLNAFSCKNL 426
Query: 799 DGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKR 854
G Y C C G++ G NC +V++C CQ C + Y+C C G+ R
Sbjct: 427 IGGYYCDCIPGWK----GINCHINVNDCRGQ---CQHGGTCKDLVNGYQCVCPRGFGGR 478
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 9/92 (9%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC- 819
FRC C PG++ G CA + P PC C + S+ C+CR G+E G C
Sbjct: 719 FRCACPPGWK--GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWE----GRTCT 772
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
+ ++C IC + + C C G+
Sbjct: 773 HNTNDCNPLPCYNGGICVDGVNWFRCECAPGF 804
Score = 47.6 bits (108), Expect = 2e-04
Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 9/93 (9%)
Query: 760 PGRFRCVCGPGYRPAGEVCADVDE-CAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
P ++RC C GY +G C + C P CH ++C C +G+ G
Sbjct: 312 PDQYRCTCPDGY--SGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGW----SGPT 365
Query: 819 C--RDVDECERDTHTCQQICSNTEGSYECSCED 849
C D+DEC + C + +EC C +
Sbjct: 366 CASADIDECASNPCAAGGTCVDQVDGFECICPE 398
Score = 46.4 bits (105), Expect = 4e-04
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 12/109 (11%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C + PG G F C+C G+ G C + +D+C +P C + ++ C C +G
Sbjct: 597 CVSQPG----GNFSCICDSGF--TGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSG 650
Query: 810 YELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
+E + N D C D + C + + C+C+DG+ +G C
Sbjct: 651 WEGELCDTNPND---CLPDPCHSRGRCYDLVNDFYCACDDGW--KGKTC 694
Score = 42.7 bits (96), Expect = 0.005
Identities = 41/134 (30%), Positives = 56/134 (41%), Gaps = 36/134 (26%)
Query: 749 DECAAIP----GLC---APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQ--LCHNT 798
DECA+ P GLC A G F C C G+ +G +C DVD C P PC C+N
Sbjct: 485 DECASSPCHSGGLCEDLADG-FHCHCPQGF--SGPLCEVDVDLC--EPSPCRNGARCYNL 539
Query: 799 DGSYDCLCRTGY-----ELDED---GANCRDVDECERDT------HTCQQIC-------S 837
+G Y C C + + + G CR +D C D +C S
Sbjct: 540 EGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVS 599
Query: 838 NTEGSYECSCEDGY 851
G++ C C+ G+
Sbjct: 600 QPGGNFSCICDSGF 613
Score = 41.9 bits (94), Expect = 0.009
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 14/100 (14%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC 819
F C+C G+ G C + ++C P PC +C + + C C G+ G +C
Sbjct: 758 FSCICRDGWE--GRTCTHNTNDC--NPLPCYNGGICVDGVNWFRCECAPGFA----GPDC 809
Query: 820 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
R ++DEC+ C + Y CSC G + G C
Sbjct: 810 RINIDECQSSPCAYGATCVDEINGYRCSCPPG--RAGPRC 847
Score = 35.9 bits (79), Expect = 0.61
Identities = 22/95 (23%), Positives = 39/95 (41%), Gaps = 9/95 (9%)
Query: 763 FRCVCGPGYRPAGEVCADVD-ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 821
F C C G++ G+ C + +C C+++ ++ C C G++ G+ C
Sbjct: 681 FYCACDDGWK--GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWK----GSTCAV 734
Query: 822 VDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKR 854
+ C C + S+ C C DG+E R
Sbjct: 735 AKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGR 769
Score = 35.1 bits (77), Expect = 1.1
Identities = 34/109 (31%), Positives = 41/109 (37%), Gaps = 20/109 (18%)
Query: 751 CAAIPGLCA-PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C + G C PG RC Y G C DEC P C + C C T
Sbjct: 233 CNLLHGGCTVPGECRC----SYGWQGRFC---DECVPYPGCVHGSCVEP---WQCNCETN 282
Query: 810 YELDEDGANC-RDVDECERDTHTCQQ--ICSNTE-GSYECSCEDGYEKR 854
+ G C +D++ C H C C N E Y C+C DGY R
Sbjct: 283 W----GGLLCDKDLNYCGSH-HPCTNGGTCINAEPDQYRCTCPDGYSGR 326
>AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 189 bits (461), Expect = 3e-47
Identities = 166/563 (29%), Positives = 241/563 (42%), Gaps = 80/563 (14%)
Query: 92 CGCDHGYEHDNTSHLCRDVDEC---SWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD 148
C C GY T H +D+DEC G PC C+N PG+F C CPPGY T S
Sbjct: 418 CLCQPGYSGP-TCH--QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGS-- 470
Query: 149 ECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGT 206
CE D +EC Q C + + ++ C C PG L +C + +EC+ P +
Sbjct: 471 RCEADHNECLSQPCHPGSTCLDLLATFHCLCPPG--LEGQLCEVETNECA-SAPCLNHAD 527
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTL 265
C +L + C C GF + D++ECR C N G+C++ G+F C+C PG+
Sbjct: 528 CHDLLNGFQCICLPGFSGTRCEE--DIDECRSS--PCANGGQCQDQPGAFHCKCLPGF-- 581
Query: 266 TADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKEL 324
+G C+ +VDEC P P G SC + G + C C +G+ G+ C + C
Sbjct: 582 --EGPRCQTEVDECLSDPCPVG----ASCLDLPGAFFCLCPSGF--TGQLC-EVPLC--A 630
Query: 325 PYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRAR---PL 380
P +C + C++ C CP D + E C+ G C R+ +
Sbjct: 631 PNLCQPKQICKDQKDKANCLCP-----DGSPGCAPPEDNCTCHH----GHCQRSSCVCDV 681
Query: 381 QLARPEC------CCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP 434
PEC C S A G C P + + C G P ++++ C P
Sbjct: 682 GWTGPECEAELGGCISAPCAHGGTC----YPQPSGYNCTCPTGYTGPTCSEEMTACHSGP 737
Query: 435 DVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYE 492
C+ GG C + G + C CP + G C D C P G GTC N G +
Sbjct: 738 --CLNGGSCNPSPGGYYCTCPPSHT----GPQCQTSTDYCVSAPCFNG-GTCVNRPGTFS 790
Query: 493 CQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI- 551
C C+ GF QGP CA+ C ++ RC CP Y G C+ +
Sbjct: 791 CLCAMGF-QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTVYT----GGSCQTLM 845
Query: 552 DECVQEPRVCPH--ACENVVGSYICKCPEGYR--RTSAPQDSENACEDINECEEQEDLC- 606
D C Q+P CP C S+ C C +G+ + P S +++ + LC
Sbjct: 846 DLCAQKP--CPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAA-LSQGIDVSSLCH 902
Query: 607 SGGVCINTDGSFLCDCDAGFEPS 629
+GG+C+++ S+ C C GF+ S
Sbjct: 903 NGGLCVDSGPSYFCHCPPGFQGS 925
Score = 183 bits (445), Expect = 3e-45
Identities = 190/641 (29%), Positives = 254/641 (39%), Gaps = 118/641 (18%)
Query: 33 APCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKP----GTCHDTPT 88
A C P GS LC +PG Y P ++ +DEC + Q P G+C +TP
Sbjct: 405 AQCSTNPLTGS----TLCLCQPG-YSGPTCHQD--LDECLMAQQGPSPCEHGGSCLNTPG 457
Query: 89 GFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
F C C GY T C D +EC PC + C++L F C CPPG L L
Sbjct: 458 SFNCLCPPGY----TGSRCEADHNECL--SQPCHPGSTCLDLLATFHCLCPPG--LEGQL 509
Query: 148 DECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTC 207
E E +EC +H DC + + ++C C PG++ D+DEC R P G C
Sbjct: 510 CEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS-GTRCEEDIDEC-RSSPCANGGQC 566
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYT-- 264
++ PGA+ C C GF+ GP +V+EC C G C + G+F C C G+T
Sbjct: 567 QDQPGAFHCKCLPGFE-GPRCQ-TEVDECLSD--PCPVGASCLDLPGAFFCLCPSGFTGQ 622
Query: 265 ----------LTADGRNCRDVDECDELPHPCGRDG----NPSCTNTNGGYE---CSCGAG 307
L + C+D + P G G +CT +G + C C G
Sbjct: 623 LCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVG 682
Query: 308 WKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
W G C + C P CA GG C GY C CP G+ T C E C
Sbjct: 683 W--TGPECEAELGGCISAP--CAHGGTCYPQPSGYNCTCPTGY----TGPTC-SEEMTAC 733
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
+ +G C L C S G G YC CP + P
Sbjct: 734 H----SGPC-------LNGGSCNPSPG---GYYC-TCPPSHTG------------PQCQT 766
Query: 426 DLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVD--ADECALDPRICGN- 481
D C P C GG CVN G+F C C G+ G C CA P C N
Sbjct: 767 STDYCVSAP--CFNGGTCVNRPGTFSCLCAMGF----QGPRCEGKLRPSCADSP--CRNR 818
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA- 540
TC ++ G C C +T G QT +D+ CA+ C T SF C C G+
Sbjct: 819 ATCQDSPQGPRCLCPTVYTGGSCQTLMDL--CAQKPCPRNSHCLQTGPSFHCLCLQGWTG 876
Query: 541 ----VAADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENACE 594
+ + + + +C + C + SY C CP G+ + S QD N CE
Sbjct: 877 PLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF-QGSLCQDHVNPCE 935
Query: 595 DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
C+ +G C+ +LC C G+ DG +C
Sbjct: 936 S-RPCQ------NGATCMAQPSGYLCQCAPGY----DGQNC 965
Score = 178 bits (433), Expect = 8e-44
Identities = 182/654 (27%), Positives = 268/654 (40%), Gaps = 107/654 (16%)
Query: 21 YLCCCSVGHAWGAPCEA-----CPP----RGSPAHTALCGEKPGEYINPVTNETKPI-DE 70
+LC C G G C+A CPP + H G + T E + D
Sbjct: 101 FLCTCLPGFT-GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDF 159
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNL 129
C P + G C T QC C G+E H C RDV+EC PC C N
Sbjct: 160 CSANPCV-NGGVCLATYPQIQCHCPPGFE----GHACERDVNECFQDPGPCPKGTSCHNT 214
Query: 130 PGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCR----NTIGSYRCECKPGYTL 184
G+F+C CP G P CE C + + G C+ + C C PG+ +
Sbjct: 215 LGSFQCLCPVGQE-GP---RCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGF-I 269
Query: 185 RENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCV-DVNECR-EGGM 241
+ + D C + C+NG TC++ Y C C + + DC DV+EC +G
Sbjct: 270 GPDCEVNPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGW---DCSEDVDECETQGPP 324
Query: 242 VCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGG 299
CRNG C+N+ GSF C C G+ G +C + +D+C + C +C + G
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDC--IAATCA--PGSTCIDRVGS 376
Query: 300 YECSCGAGWKLVGRRCVDRDECKELPYVCAG-GECRN--FNGGYVCECPAGWRFDKTAAV 356
+ C C G G C D C P C G +C G +C C G+ +
Sbjct: 377 FSCLCPPG--RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTLCLCQPGY----SGPT 428
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
C + E C A+ Q P C G + C P F +C
Sbjct: 429 CHQDLDE----------CLMAQ--QGPSP---CEHGGS----CLNTP----GSFNCLCPP 465
Query: 417 GMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALD 475
G D +EC +P G C++ +F C CP G +G C V+ +ECA
Sbjct: 466 GYTGSRCEADHNECLSQP-CHPGSTCLDLLATFHCLCPPGL----EGQLCEVETNECASA 520
Query: 476 PRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
P + + C + G++C C PGF+ + D+DEC + +C + G+F C C
Sbjct: 521 PCL-NHADCHDLLNGFQCICLPGFSGTRCEE--DIDECRSSPCANGGQCQDQPGAFHCKC 577
Query: 536 PYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGY--RRTSAPQDSENA 592
G+ +G C+ ++DEC+ +P +C ++ G++ C CP G+ + P + N
Sbjct: 578 LPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNL 633
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS 646
C+ C++Q+D + C+ DGS G P ED C G C RS
Sbjct: 634 CQPKQICKDQKDKAN---CLCPDGS------PGCAPPEDNCTC---HHGHCQRS 675
Score = 168 bits (409), Expect = 6e-41
Identities = 168/571 (29%), Positives = 220/571 (38%), Gaps = 101/571 (17%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P G C D P F C C G+E +VDEC PC A C+
Sbjct: 552 IDECRSSP-CANGGQCQDQPGAFHCKCLPGFEGPRCQ---TEVDECL--SDPCPVGASCL 605
Query: 128 NLPGAFECRCPPGYR--------LTPSLDECEDVDECGDQR-----ICDHGDCRNTIGSY 174
+LPGAF C CP G+ P+L C+ C DQ+ +C G
Sbjct: 606 DLPGAFFCLCPSGFTGQLCEVPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPED 663
Query: 175 RCECKPGYTLRENVCRDVD----ECSRP------RPVCRNGTCENLPGAYLCHCDDGFKA 224
C C G+ R + DV EC P GTC P Y C C G+
Sbjct: 664 NCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY-T 722
Query: 225 GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPH 283
GP C + G G C + G + C C P +T G C+ D C +
Sbjct: 723 GPT--CSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT----GPQCQTSTDYC--VSA 774
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVD--RDECKELPYVCAG-GECRNFNGGY 340
PC G +C N G + C C G++ G RC R C + P C C++ G
Sbjct: 775 PCFNGG--TCVNRPGTFSCLCAMGFQ--GPRCEGKLRPSCADSP--CRNRATCQDSPQGP 828
Query: 341 VCECPA---GWRFDKTAAVCVDE---RKE-----------LCYDEWEAGRCHRARPLQLA 383
C CP G +C + R LC W C+ PL
Sbjct: 829 RCLCPTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNL--PLSSC 886
Query: 384 RPECCCSEGAAWGRYCER---CPAPDSAEFMRICQGGMGRPNLTQD-LDECRVRPDVCVG 439
+ + S+G C C + F G G +L QD ++ C RP C
Sbjct: 887 Q-KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQG--SLCQDHVNPCESRP--CQN 941
Query: 440 GR-CVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGN-GTCSNTRGGYECQCS 496
G C+ + C+C GY DG +C + D C P C N GTC+ GG+ C C
Sbjct: 942 GATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQP--CHNHGTCTPKPGGFHCACP 995
Query: 497 PGFTQGPDQTCV-DVDECAEG--RASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DID 552
PGF C DVDEC + + T CH+ A +F C C G+ G C +ID
Sbjct: 996 PGFV---GLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT----GQWCEVEID 1048
Query: 553 ECVQEPRVCPHACENVVGS---YICKCPEGY 580
C +P CE GS +IC CP+G+
Sbjct: 1049 PCHSQPCFHGGTCEATAGSPLGFICHCPKGF 1079
Score = 167 bits (405), Expect = 2e-40
Identities = 186/634 (29%), Positives = 259/634 (40%), Gaps = 125/634 (19%)
Query: 66 KPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+ ++EC P C GT CH+T FQC C G E C E G P RG +
Sbjct: 193 RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPR----C----ELRAGPCPPRGCS 244
Query: 125 Q---CVNLP---GAFE-CRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRC 176
C +P F C CPPG+ + P +CE + D C + + G C++ + +Y C
Sbjct: 245 NGGTCQLMPEKDSTFHLCLCPPGF-IGP---DCEVNPDNCVSHQCQNGGTCQDGLDTYTC 300
Query: 177 ECKPGYTLRENVCRDVDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVN 234
C +T + DVDEC ++ P CRNG TC+N G++ C C G+ G + +++
Sbjct: 301 LCPETWT-GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW--GGTSCEENLD 357
Query: 235 ECREGGMVCRNGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+C C G C + VGSF C C PG T G C D C L PC D S
Sbjct: 358 DCIAA--TCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMC--LSQPCHGDAQCST 409
Query: 294 TNTNGGYECSCGAGWKLVGRRC-VDRDEC---KELPYVCA-GGECRNFNGGYVCECPAGW 348
G C C G+ G C D DEC ++ P C GG C N G + C CP G+
Sbjct: 410 NPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 467
Query: 349 RFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSA 408
T + C + E C + CH P C + A
Sbjct: 468 ----TGSRCEADHNE-CLSQ----PCH---------PGSTCLDLLA-------------- 495
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCV 467
F +C G+ + +EC P C+ C + F+C C G+ G C
Sbjct: 496 TFHCLCPPGLEGQLCEVETNECASAP--CLNHADCHDLLNGFQCICLPGF----SGTRCE 549
Query: 468 -DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
D DEC P C NG C + G + C+C PGF +GP + +VDEC C
Sbjct: 550 EDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF-EGP-RCQTEVDECLSDPCPVGASCL 605
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRT 583
+ G+F C CP G+ G C ++ C P +C C++ C CP+G
Sbjct: 606 DLPGAFFCLCPSGFT----GQLC-EVPLCA--PNLCQPKQICKDQKDKANCLCPDGSPGC 658
Query: 584 SAPQDS---------ENACE-DIN----ECEEQEDLC------SGGVCINTDGSFLCDCD 623
+ P+D+ ++C D+ ECE + C GG C + C C
Sbjct: 659 APPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 718
Query: 624 AGFEP---SEDGTDCIDRRTGTCYRSLVSGRCEP 654
G+ SE+ T C +G C L G C P
Sbjct: 719 TGYTGPTCSEEMTAC---HSGPC---LNGGSCNP 746
Score = 145 bits (351), Expect = 7e-34
Identities = 153/527 (29%), Positives = 211/527 (40%), Gaps = 105/527 (19%)
Query: 165 GDCRN-TIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCE-------NLPGA-- 213
G C + ++G C+C PG+ L E C+ D C + +C+NG +C+ LP +
Sbjct: 39 GTCLSLSLGQGTCQCAPGF-LGET-CQFPDPCQNAQ-LCQNGGSCQALLPAPLGLPSSPS 95
Query: 214 -----YLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCR-NTVGSFRCECAPGYTLTA 267
+LC C GF G + C + GRC G +C C PG+T
Sbjct: 96 PLTPSFLCTCLPGF-TGERCQAKLEDPCPPS-FCSKRGRCHIQASGRPQCSCMPGWT--- 150
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV-DRDECKELPY 326
G C+ D C +PC G C T +C C G++ G C D +EC + P
Sbjct: 151 -GEQCQLRDFCSA--NPCVNGG--VCLATYPQIQCHCPPGFE--GHACERDVNECFQDPG 203
Query: 327 VCAGG-ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARP 385
C G C N G + C CP G + C E AG C P
Sbjct: 204 PCPKGTSCHNTLGSFQCLCPVG------------QEGPRC--ELRAGPC----------P 239
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN- 444
CS G C+ P DS + +C G P +C V PD CV +C N
Sbjct: 240 PRGCSNGGT----CQLMPEKDSTFHLCLCPPGFIGP-------DCEVNPDNCVSHQCQNG 288
Query: 445 ---TDG--SFRCECPDGYVLAPDGLSCV-DADECALD-PRICGNG-TCSNTRGGYECQCS 496
DG ++ C CP+ + G C D DEC P C NG TC N+ G + C C
Sbjct: 289 GTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
Query: 497 PGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
G+ G ++D+C + C + GSF C CP G G+ C D C+
Sbjct: 345 SGW--GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMCLS 398
Query: 557 EPRVCPHACEN--VVGSYICKCPEGYRRTSAPQDSEN---ACEDINECEEQEDLCSGGVC 611
+P C + GS +C C GY + QD + A + + CE GG C
Sbjct: 399 QPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH------GGSC 452
Query: 612 INTDGSFLCDCDAGFEPSE---DGTDCIDRRT---GTCYRSLVSGRC 652
+NT GSF C C G+ S D +C+ + TC L + C
Sbjct: 453 LNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 499
Score = 105 bits (251), Expect = 9e-22
Identities = 83/256 (32%), Positives = 114/256 (44%), Gaps = 44/256 (17%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
++ C+ P C+ G TC P+G+ C C GY+ N S +++D C PC C
Sbjct: 931 VNPCESRP--CQNGATCMAQPSGYLCQCAPGYDGQNCS---KELDACQ--SQPCHNHGTC 983
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGD--CRNTIGSYRCECKPGYT 183
PG F C CPPG+ L CE DVDEC DQ G C + ++ C+C PG+T
Sbjct: 984 TPKPGGFHCACPPGF---VGL-RCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT 1039
Query: 184 LRENVCR-DVDECSRPRPVCRNGTCENLPGA---YLCHCDDGFKAGP----NNDCVDVNE 235
C ++D C +P GTCE G+ ++CHC GF+ GP +
Sbjct: 1040 --GQWCEVEIDPC-HSQPCFHGGTCEATAGSPLGFICHCPKGFE-GPTCSHRAPSCGFHH 1095
Query: 236 CREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE---CDELPHPCGRDGNPS 292
C GG+ + + RC C GY G +C C P PC +G S
Sbjct: 1096 CHHGGLCLPSPKPGFPP---RCACLSGY----GGPDCLTPPAPKGCGP-PSPCLYNG--S 1145
Query: 293 CTNTNG----GYECSC 304
C+ T G G+ CSC
Sbjct: 1146 CSETTGLGGPGFRCSC 1161
Score = 96.7 bits (230), Expect = 3e-19
Identities = 119/412 (28%), Positives = 163/412 (39%), Gaps = 91/412 (22%)
Query: 243 CRNG-RCRN-TVGSFRCECAPGYTLTADGRNCRDVDECDE-------------LPHPCGR 287
C NG C + ++G C+CAPG+ G C+ D C LP P G
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFL----GETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 90
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECR-NFNGGYVCECP 345
+PS + + C+C G+ G RC + E P C+ G C +G C C
Sbjct: 91 PSSPSPLTPS--FLCTCLPGF--TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCE-RCPA 404
GW T C + ++ C A P C + G Y + +C
Sbjct: 147 PGW----TGEQC--QLRDFC----------SANP--------CVNGGVCLATYPQIQCHC 182
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDG 463
P E C+ +D++EC P C G C NT GSF+C CP G +G
Sbjct: 183 PPGFE-GHACE---------RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEG 228
Query: 464 LSC-VDADECALDPRICGN-GTC----SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGR 517
C + A C PR C N GTC + C C PGF GPD V+ D C +
Sbjct: 229 PRCELRAGPC--PPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI-GPDCE-VNPDNCVSHQ 284
Query: 518 ASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDEC-VQEPRVCPH--ACENVVGSYI 573
C + ++ C CP + G C D+DEC Q P C + C+N GS+
Sbjct: 285 CQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
C C G+ TS E++++C G CI+ GSF C C G
Sbjct: 341 CVCVSGWGGTSCE-------ENLDDC-IAATCAPGSTCIDRVGSFSCLCPPG 384
Score = 94.3 bits (224), Expect = 2e-18
Identities = 130/513 (25%), Positives = 177/513 (34%), Gaps = 80/513 (15%)
Query: 380 LQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG 439
L L + C C+ G E C PD + ++CQ G L P
Sbjct: 44 LSLGQGTCQCAPGFLG----ETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 99
Query: 440 GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGN-GTCS-NTRGGYECQCSP 497
SF C C G+ G C E P C G C G +C C P
Sbjct: 100 --------SFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMP 147
Query: 498 GFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQ 556
G+T + C D C+ C T +C CP G+ +G C RD++EC Q
Sbjct: 148 GWT---GEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQ 200
Query: 557 EPRVCPH--ACENVVGSYICKCP---EGYR-RTSAPQDSENACEDINECEEQEDLCSG-G 609
+P CP +C N +GS+ C CP EG R A C + C+ + S
Sbjct: 201 DPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFH 260
Query: 610 VCINTDGSFLCDCDAGFE-----PSEDGTDC---IDRRTGTCYRSLVSGRCEPEXXXXXX 661
+C+ G DC+ + ++G C +D T C + C +
Sbjct: 261 LCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECET 320
Query: 662 XXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWG-SECELCPAPGSPARLDLCTAVNLTPX 720
G C C G WG + CE LD C A P
Sbjct: 321 QGPPHCRNGGTCQNSAGSF---HCVCVSG--WGGTSCE--------ENLDDCIAATCAPG 367
Query: 721 XXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP----GLCAP----GRFRCVCGPGYR 772
L D+ C + P C+ G C+C PGY
Sbjct: 368 STCIDRVGSFSCLCPPGRTGLLCHLEDM--CLSQPCHGDAQCSTNPLTGSTLCLCQPGY- 424
Query: 773 PAGEVC-ADVDECAVR---PPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR-DVDEC 825
+G C D+DEC + P PC+ C NT GS++CLC GY G+ C D +EC
Sbjct: 425 -SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNEC 479
Query: 826 ERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
C + ++ C C G E G C
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLE--GQLC 510
Score = 77.4 bits (182), Expect = 2e-13
Identities = 113/396 (28%), Positives = 139/396 (35%), Gaps = 79/396 (19%)
Query: 21 YLCCCSVGHAWGAPCE--ACPPRGSPAHT-ALCGEKPGEYINPVT------NETKPIDEC 71
Y C C G G+ C+ P P A C +P Y+ N +K +D C
Sbjct: 914 YFCHCPPGFQ-GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDAC 972
Query: 72 DIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCR--GMAQCV 127
P C GTC P GF C C G+ C DVDEC PC G A C
Sbjct: 973 QSQP--CHNHGTCTPKPGGFHCACPPGF----VGLRCEGDVDECL--DQPCHPTGTAACH 1024
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGS---YRCECKPGYTL 184
+L AF C+C PG+ T E E +D C Q G C T GS + C C G+
Sbjct: 1025 SLANAFYCQCLPGH--TGQWCEVE-IDPCHSQPCFHGGTCEATAGSPLGFICHCPKGF-- 1079
Query: 185 RENVCRDVDECSRPRPVC------RNGTCENLPGAYL---CHCDDGFKAGPNNDCVDV-- 233
+ CS P C G C P C C G+ GP DC+
Sbjct: 1080 ------EGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGY-GGP--DCLTPPA 1130
Query: 234 -NECREGGMVCRNGRCRNTVG----SFRCEC---APGYTLTADG-RNCRDVDECDELPHP 284
C NG C T G FRC C +PG G + C
Sbjct: 1131 PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAG 1190
Query: 285 CGRDGNPSCTNTNGGYECSCGAG--WKLVGR--RCVDRDECKELPYVCAGGECRNFNGGY 340
C G N +GG +CS G WK RC + C EC F+G Y
Sbjct: 1191 CSGPGG----NWDGG-DCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECL-FDG-Y 1243
Query: 341 VCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHR 376
CE P C + C+D + G C +
Sbjct: 1244 DCETPPA---------CTPAYDQYCHDHFHNGHCEK 1270
Score = 71.7 bits (168), Expect = 1e-11
Identities = 108/408 (26%), Positives = 142/408 (34%), Gaps = 80/408 (19%)
Query: 472 CALDPRICGNG-TC-SNTRGGYECQCSPGF----TQGPDQTCVDVDECAEGRASCTFRCH 525
C P C NG TC S + G CQC+PGF Q PD C + C G SC
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNG-GSCQALLP 85
Query: 526 NTAG----------SFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH--ACE-NVVGSY 572
G SF CTC G+ G C+ E P C C G
Sbjct: 86 APLGLPSSPSPLTPSFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRP 141
Query: 573 ICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDG 632
C C G+ T + C N C +GGVC+ T C C GFE G
Sbjct: 142 QCSCMPGW--TGEQCQLRDFC-SANPC------VNGGVCLATYPQIQCHCPPGFE----G 188
Query: 633 TDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAA 692
C +R C++ G C P+ +A C G +
Sbjct: 189 HAC-ERDVNECFQD--PGPC-PKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCS 244
Query: 693 WGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECA 752
G C+L P S L LC + P D + D C
Sbjct: 245 NGGTCQLMPEKDSTFHLCLCPPGFIGP-----------------------DCEVNPDNCV 281
Query: 753 AIP----GLCAPG--RFRCVCGPGYRPAGEVCADVDECAVR-PPPCDQ--LCHNTDGSYD 803
+ G C G + C+C P + DVDEC + PP C C N+ GS+
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLC-PETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340
Query: 804 CLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDG 850
C+C +G+ G +C + +D+C T C + GS+ C C G
Sbjct: 341 CVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG 384
Score = 62.5 bits (145), Expect = 6e-09
Identities = 39/111 (35%), Positives = 53/111 (47%), Gaps = 14/111 (12%)
Query: 747 DVDECAAIP----GLCA--PGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D+DEC + P G C PG F C C PG+ G C +VDEC P P C +
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFE--GPRCQTEVDECLSDPCPVGASCLDLP 608
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
G++ CLC +G+ G C +V C + +QIC + + C C DG
Sbjct: 609 GAFFCLCPSGF----TGQLC-EVPLCAPNLCQPKQICKDQKDKANCLCPDG 654
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 18/117 (15%)
Query: 746 ADVDECAAIPGLCAPGR--------FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCH 796
AD +EC + P C PG F C+C PG G++C + +ECA P CH
Sbjct: 474 ADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE--GQLCEVETNECASAPCLNHADCH 529
Query: 797 NTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+ + C+C G+ G C D+DEC C + G++ C C G+E
Sbjct: 530 DLLNGFQCICLPGFS----GTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE 582
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/113 (31%), Positives = 54/113 (47%), Gaps = 14/113 (12%)
Query: 747 DVDECAAIPGL----CAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+ +ECA+ P L C F+C+C PG+ +G C D+DEC P C +
Sbjct: 513 ETNECASAPCLNHADCHDLLNGFQCICLPGF--SGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G++ C C G+E G C+ +VDEC D C + G++ C C G+
Sbjct: 571 GAFHCKCLPGFE----GPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGF 619
Score = 54.4 bits (125), Expect = 2e-06
Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 10/109 (9%)
Query: 747 DVDECAAIPGLCAPG--RFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYD 803
DV GLC + C C PG++ G +C D V+ C RP C Y
Sbjct: 896 DVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHVNPCESRPCQNGATCMAQPSGYL 953
Query: 804 CLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C C GY DG NC +++D C+ C+ G + C+C G+
Sbjct: 954 CQCAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGF 998
Score = 48.4 bits (110), Expect = 1e-04
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 8/97 (8%)
Query: 757 LCAPGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 815
L PG F C+C PGY G C AD +EC +P C + ++ CLC G E
Sbjct: 453 LNTPGSFNCLCPPGY--TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE---- 506
Query: 816 GANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C + +EC C + ++C C G+
Sbjct: 507 GQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 543
Score = 42.3 bits (95), Expect = 0.007
Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 10/101 (9%)
Query: 749 DECAAIPGLCAPGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCR 807
D C G C R CVC G+ G C A++ C P C+ Y+C C
Sbjct: 663 DNCTCHHGHCQ--RSSCVCDVGW--TGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 718
Query: 808 TGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSC 847
TGY G C ++ C C+ + G Y C+C
Sbjct: 719 TGY----TGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 755
Score = 40.3 bits (90), Expect = 0.028
Identities = 33/124 (26%), Positives = 48/124 (38%), Gaps = 18/124 (14%)
Query: 746 ADVDECAAIP----GLC--APGRFRCVCGPGYRPAGEVCADVDECAVRPPPC--DQLCHN 797
A++ C + P G C P + C C GY G C++ + A PC C+
Sbjct: 690 AELGGCISAPCAHGGTCYPQPSGYNCTCPTGY--TGPTCSE-EMTACHSGPCLNGGSCNP 746
Query: 798 TDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
+ G Y C C + G C+ D C C N G++ C C G++ G
Sbjct: 747 SPGGYYCTCPPSHT----GPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQ--GP 800
Query: 857 ACVG 860
C G
Sbjct: 801 RCEG 804
Score = 36.7 bits (81), Expect = 0.35
Identities = 23/78 (29%), Positives = 31/78 (39%), Gaps = 5/78 (6%)
Query: 759 APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
+PG + C C P + G C D C P C N G++ CLC G++
Sbjct: 747 SPGGYYCTCPPSH--TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEG 804
Query: 818 NCRD--VDECERDTHTCQ 833
R D R+ TCQ
Sbjct: 805 KLRPSCADSPCRNRATCQ 822
Score = 36.7 bits (81), Expect = 0.35
Identities = 29/106 (27%), Positives = 44/106 (41%), Gaps = 18/106 (16%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DV 822
RC+C P G +D CA +P P + C T S+ CLC G+ G C +
Sbjct: 829 RCLC-PTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGW----TGPLCNLPL 883
Query: 823 DECERD--------THTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
C++ + C +C ++ SY C C G++ G C
Sbjct: 884 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLC 927
Score = 35.1 bits (77), Expect = 1.1
Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 14/73 (19%)
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDG 850
LC ++ SY C C G++ G+ C+D V+ CE + CQ C Y C C G
Sbjct: 906 LCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPG 959
Query: 851 YE-----KRGDAC 858
Y+ K DAC
Sbjct: 960 YDGQNCSKELDAC 972
>AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 189 bits (461), Expect = 3e-47
Identities = 166/563 (29%), Positives = 241/563 (42%), Gaps = 80/563 (14%)
Query: 92 CGCDHGYEHDNTSHLCRDVDEC---SWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLD 148
C C GY T H +D+DEC G PC C+N PG+F C CPPGY T S
Sbjct: 418 CLCQPGYSGP-TCH--QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGS-- 470
Query: 149 ECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGT 206
CE D +EC Q C + + ++ C C PG L +C + +EC+ P +
Sbjct: 471 RCEADHNECLSQPCHPGSTCLDLLATFHCLCPPG--LEGQLCEVETNECA-SAPCLNHAD 527
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTL 265
C +L + C C GF + D++ECR C N G+C++ G+F C+C PG+
Sbjct: 528 CHDLLNGFQCICLPGFSGTRCEE--DIDECRSS--PCANGGQCQDQPGAFHCKCLPGF-- 581
Query: 266 TADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKEL 324
+G C+ +VDEC P P G SC + G + C C +G+ G+ C + C
Sbjct: 582 --EGPRCQTEVDECLSDPCPVG----ASCLDLPGAFFCLCPSGF--TGQLC-EVPLC--A 630
Query: 325 PYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRAR---PL 380
P +C + C++ C CP D + E C+ G C R+ +
Sbjct: 631 PNLCQPKQICKDQKDKANCLCP-----DGSPGCAPPEDNCTCHH----GHCQRSSCVCDV 681
Query: 381 QLARPEC------CCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP 434
PEC C S A G C P + + C G P ++++ C P
Sbjct: 682 GWTGPECEAELGGCISAPCAHGGTC----YPQPSGYNCTCPTGYTGPTCSEEMTACHSGP 737
Query: 435 DVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYE 492
C+ GG C + G + C CP + G C D C P G GTC N G +
Sbjct: 738 --CLNGGSCNPSPGGYYCTCPPSHT----GPQCQTSTDYCVSAPCFNG-GTCVNRPGTFS 790
Query: 493 CQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI- 551
C C+ GF QGP CA+ C ++ RC CP Y G C+ +
Sbjct: 791 CLCAMGF-QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTVYT----GGSCQTLM 845
Query: 552 DECVQEPRVCPH--ACENVVGSYICKCPEGYR--RTSAPQDSENACEDINECEEQEDLC- 606
D C Q+P CP C S+ C C +G+ + P S +++ + LC
Sbjct: 846 DLCAQKP--CPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAA-LSQGIDVSSLCH 902
Query: 607 SGGVCINTDGSFLCDCDAGFEPS 629
+GG+C+++ S+ C C GF+ S
Sbjct: 903 NGGLCVDSGPSYFCHCPPGFQGS 925
Score = 183 bits (445), Expect = 3e-45
Identities = 190/641 (29%), Positives = 254/641 (39%), Gaps = 118/641 (18%)
Query: 33 APCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKP----GTCHDTPT 88
A C P GS LC +PG Y P ++ +DEC + Q P G+C +TP
Sbjct: 405 AQCSTNPLTGS----TLCLCQPG-YSGPTCHQD--LDECLMAQQGPSPCEHGGSCLNTPG 457
Query: 89 GFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
F C C GY T C D +EC PC + C++L F C CPPG L L
Sbjct: 458 SFNCLCPPGY----TGSRCEADHNECL--SQPCHPGSTCLDLLATFHCLCPPG--LEGQL 509
Query: 148 DECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTC 207
E E +EC +H DC + + ++C C PG++ D+DEC R P G C
Sbjct: 510 CEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS-GTRCEEDIDEC-RSSPCANGGQC 566
Query: 208 ENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYT-- 264
++ PGA+ C C GF+ GP +V+EC C G C + G+F C C G+T
Sbjct: 567 QDQPGAFHCKCLPGFE-GPRCQ-TEVDECLSD--PCPVGASCLDLPGAFFCLCPSGFTGQ 622
Query: 265 ----------LTADGRNCRDVDECDELPHPCGRDG----NPSCTNTNGGYE---CSCGAG 307
L + C+D + P G G +CT +G + C C G
Sbjct: 623 LCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVG 682
Query: 308 WKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
W G C + C P CA GG C GY C CP G+ T C E C
Sbjct: 683 W--TGPECEAELGGCISAP--CAHGGTCYPQPSGYNCTCPTGY----TGPTC-SEEMTAC 733
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ 425
+ +G C L C S G G YC CP + P
Sbjct: 734 H----SGPC-------LNGGSCNPSPG---GYYC-TCPPSHTG------------PQCQT 766
Query: 426 DLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVD--ADECALDPRICGN- 481
D C P C GG CVN G+F C C G+ G C CA P C N
Sbjct: 767 STDYCVSAP--CFNGGTCVNRPGTFSCLCAMGF----QGPRCEGKLRPSCADSP--CRNR 818
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA- 540
TC ++ G C C +T G QT +D+ CA+ C T SF C C G+
Sbjct: 819 ATCQDSPQGPRCLCPTVYTGGSCQTLMDL--CAQKPCPRNSHCLQTGPSFHCLCLQGWTG 876
Query: 541 ----VAADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENACE 594
+ + + + +C + C + SY C CP G+ + S QD N CE
Sbjct: 877 PLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF-QGSLCQDHVNPCE 935
Query: 595 DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
C+ +G C+ +LC C G+ DG +C
Sbjct: 936 S-RPCQ------NGATCMAQPSGYLCQCAPGY----DGQNC 965
Score = 178 bits (433), Expect = 8e-44
Identities = 182/654 (27%), Positives = 268/654 (40%), Gaps = 107/654 (16%)
Query: 21 YLCCCSVGHAWGAPCEA-----CPP----RGSPAHTALCGEKPGEYINPVTNETKPI-DE 70
+LC C G G C+A CPP + H G + T E + D
Sbjct: 101 FLCTCLPGFT-GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDF 159
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNL 129
C P + G C T QC C G+E H C RDV+EC PC C N
Sbjct: 160 CSANPCV-NGGVCLATYPQIQCHCPPGFE----GHACERDVNECFQDPGPCPKGTSCHNT 214
Query: 130 PGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCR----NTIGSYRCECKPGYTL 184
G+F+C CP G P CE C + + G C+ + C C PG+ +
Sbjct: 215 LGSFQCLCPVGQE-GP---RCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGF-I 269
Query: 185 RENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCV-DVNECR-EGGM 241
+ + D C + C+NG TC++ Y C C + + DC DV+EC +G
Sbjct: 270 GPDCEVNPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGW---DCSEDVDECETQGPP 324
Query: 242 VCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGG 299
CRNG C+N+ GSF C C G+ G +C + +D+C + C +C + G
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDC--IAATCA--PGSTCIDRVGS 376
Query: 300 YECSCGAGWKLVGRRCVDRDECKELPYVCAG-GECRN--FNGGYVCECPAGWRFDKTAAV 356
+ C C G G C D C P C G +C G +C C G+ +
Sbjct: 377 FSCLCPPG--RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTLCLCQPGY----SGPT 428
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
C + E C A+ Q P C G + C P F +C
Sbjct: 429 CHQDLDE----------CLMAQ--QGPSP---CEHGGS----CLNTP----GSFNCLCPP 465
Query: 417 GMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALD 475
G D +EC +P G C++ +F C CP G +G C V+ +ECA
Sbjct: 466 GYTGSRCEADHNECLSQP-CHPGSTCLDLLATFHCLCPPGL----EGQLCEVETNECASA 520
Query: 476 PRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
P + + C + G++C C PGF+ + D+DEC + +C + G+F C C
Sbjct: 521 PCL-NHADCHDLLNGFQCICLPGFSGTRCEE--DIDECRSSPCANGGQCQDQPGAFHCKC 577
Query: 536 PYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGY--RRTSAPQDSENA 592
G+ +G C+ ++DEC+ +P +C ++ G++ C CP G+ + P + N
Sbjct: 578 LPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNL 633
Query: 593 CEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS 646
C+ C++Q+D + C+ DGS G P ED C G C RS
Sbjct: 634 CQPKQICKDQKDKAN---CLCPDGS------PGCAPPEDNCTC---HHGHCQRS 675
Score = 168 bits (409), Expect = 6e-41
Identities = 168/571 (29%), Positives = 220/571 (38%), Gaps = 101/571 (17%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P G C D P F C C G+E +VDEC PC A C+
Sbjct: 552 IDECRSSP-CANGGQCQDQPGAFHCKCLPGFEGPRCQ---TEVDECL--SDPCPVGASCL 605
Query: 128 NLPGAFECRCPPGYR--------LTPSLDECEDVDECGDQR-----ICDHGDCRNTIGSY 174
+LPGAF C CP G+ P+L C+ C DQ+ +C G
Sbjct: 606 DLPGAFFCLCPSGFTGQLCEVPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPED 663
Query: 175 RCECKPGYTLRENVCRDVD----ECSRP------RPVCRNGTCENLPGAYLCHCDDGFKA 224
C C G+ R + DV EC P GTC P Y C C G+
Sbjct: 664 NCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY-T 722
Query: 225 GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPH 283
GP C + G G C + G + C C P +T G C+ D C +
Sbjct: 723 GPT--CSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT----GPQCQTSTDYC--VSA 774
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVD--RDECKELPYVCAG-GECRNFNGGY 340
PC G +C N G + C C G++ G RC R C + P C C++ G
Sbjct: 775 PCFNGG--TCVNRPGTFSCLCAMGFQ--GPRCEGKLRPSCADSP--CRNRATCQDSPQGP 828
Query: 341 VCECPA---GWRFDKTAAVCVDE---RKE-----------LCYDEWEAGRCHRARPLQLA 383
C CP G +C + R LC W C+ PL
Sbjct: 829 RCLCPTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNL--PLSSC 886
Query: 384 RPECCCSEGAAWGRYCER---CPAPDSAEFMRICQGGMGRPNLTQD-LDECRVRPDVCVG 439
+ + S+G C C + F G G +L QD ++ C RP C
Sbjct: 887 Q-KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQG--SLCQDHVNPCESRP--CQN 941
Query: 440 GR-CVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGN-GTCSNTRGGYECQCS 496
G C+ + C+C GY DG +C + D C P C N GTC+ GG+ C C
Sbjct: 942 GATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQP--CHNHGTCTPKPGGFHCACP 995
Query: 497 PGFTQGPDQTCV-DVDECAEG--RASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DID 552
PGF C DVDEC + + T CH+ A +F C C G+ G C +ID
Sbjct: 996 PGFV---GLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT----GQWCEVEID 1048
Query: 553 ECVQEPRVCPHACENVVGS---YICKCPEGY 580
C +P CE GS +IC CP+G+
Sbjct: 1049 PCHSQPCFHGGTCEATAGSPLGFICHCPKGF 1079
Score = 167 bits (405), Expect = 2e-40
Identities = 186/634 (29%), Positives = 259/634 (40%), Gaps = 125/634 (19%)
Query: 66 KPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
+ ++EC P C GT CH+T FQC C G E C E G P RG +
Sbjct: 193 RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPR----C----ELRAGPCPPRGCS 244
Query: 125 Q---CVNLP---GAFE-CRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRC 176
C +P F C CPPG+ + P +CE + D C + + G C++ + +Y C
Sbjct: 245 NGGTCQLMPEKDSTFHLCLCPPGF-IGP---DCEVNPDNCVSHQCQNGGTCQDGLDTYTC 300
Query: 177 ECKPGYTLRENVCRDVDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVN 234
C +T + DVDEC ++ P CRNG TC+N G++ C C G+ G + +++
Sbjct: 301 LCPETWT-GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW--GGTSCEENLD 357
Query: 235 ECREGGMVCRNGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
+C C G C + VGSF C C PG T G C D C L PC D S
Sbjct: 358 DCIAA--TCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMC--LSQPCHGDAQCST 409
Query: 294 TNTNGGYECSCGAGWKLVGRRC-VDRDEC---KELPYVCA-GGECRNFNGGYVCECPAGW 348
G C C G+ G C D DEC ++ P C GG C N G + C CP G+
Sbjct: 410 NPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 467
Query: 349 RFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSA 408
T + C + E C + CH P C + A
Sbjct: 468 ----TGSRCEADHNE-CLSQ----PCH---------PGSTCLDLLA-------------- 495
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCV 467
F +C G+ + +EC P C+ C + F+C C G+ G C
Sbjct: 496 TFHCLCPPGLEGQLCEVETNECASAP--CLNHADCHDLLNGFQCICLPGF----SGTRCE 549
Query: 468 -DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
D DEC P C NG C + G + C+C PGF +GP + +VDEC C
Sbjct: 550 EDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF-EGP-RCQTEVDECLSDPCPVGASCL 605
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRT 583
+ G+F C CP G+ G C ++ C P +C C++ C CP+G
Sbjct: 606 DLPGAFFCLCPSGFT----GQLC-EVPLCA--PNLCQPKQICKDQKDKANCLCPDGSPGC 658
Query: 584 SAPQDS---------ENACE-DIN----ECEEQEDLC------SGGVCINTDGSFLCDCD 623
+ P+D+ ++C D+ ECE + C GG C + C C
Sbjct: 659 APPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 718
Query: 624 AGFEP---SEDGTDCIDRRTGTCYRSLVSGRCEP 654
G+ SE+ T C +G C L G C P
Sbjct: 719 TGYTGPTCSEEMTAC---HSGPC---LNGGSCNP 746
Score = 145 bits (351), Expect = 7e-34
Identities = 153/527 (29%), Positives = 211/527 (40%), Gaps = 105/527 (19%)
Query: 165 GDCRN-TIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCE-------NLPGA-- 213
G C + ++G C+C PG+ L E C+ D C + +C+NG +C+ LP +
Sbjct: 39 GTCLSLSLGQGTCQCAPGF-LGET-CQFPDPCQNAQ-LCQNGGSCQALLPAPLGLPSSPS 95
Query: 214 -----YLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCR-NTVGSFRCECAPGYTLTA 267
+LC C GF G + C + GRC G +C C PG+T
Sbjct: 96 PLTPSFLCTCLPGF-TGERCQAKLEDPCPPS-FCSKRGRCHIQASGRPQCSCMPGWT--- 150
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV-DRDECKELPY 326
G C+ D C +PC G C T +C C G++ G C D +EC + P
Sbjct: 151 -GEQCQLRDFCSA--NPCVNGG--VCLATYPQIQCHCPPGFE--GHACERDVNECFQDPG 203
Query: 327 VCAGG-ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARP 385
C G C N G + C CP G + C E AG C P
Sbjct: 204 PCPKGTSCHNTLGSFQCLCPVG------------QEGPRC--ELRAGPC----------P 239
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN- 444
CS G C+ P DS + +C G P +C V PD CV +C N
Sbjct: 240 PRGCSNGGT----CQLMPEKDSTFHLCLCPPGFIGP-------DCEVNPDNCVSHQCQNG 288
Query: 445 ---TDG--SFRCECPDGYVLAPDGLSCV-DADECALD-PRICGNG-TCSNTRGGYECQCS 496
DG ++ C CP+ + G C D DEC P C NG TC N+ G + C C
Sbjct: 289 GTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
Query: 497 PGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
G+ G ++D+C + C + GSF C CP G G+ C D C+
Sbjct: 345 SGW--GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMCLS 398
Query: 557 EPRVCPHACEN--VVGSYICKCPEGYRRTSAPQDSEN---ACEDINECEEQEDLCSGGVC 611
+P C + GS +C C GY + QD + A + + CE GG C
Sbjct: 399 QPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH------GGSC 452
Query: 612 INTDGSFLCDCDAGFEPSE---DGTDCIDRRT---GTCYRSLVSGRC 652
+NT GSF C C G+ S D +C+ + TC L + C
Sbjct: 453 LNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 499
Score = 105 bits (251), Expect = 9e-22
Identities = 83/256 (32%), Positives = 114/256 (44%), Gaps = 44/256 (17%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
++ C+ P C+ G TC P+G+ C C GY+ N S +++D C PC C
Sbjct: 931 VNPCESRP--CQNGATCMAQPSGYLCQCAPGYDGQNCS---KELDACQ--SQPCHNHGTC 983
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGD--CRNTIGSYRCECKPGYT 183
PG F C CPPG+ L CE DVDEC DQ G C + ++ C+C PG+T
Sbjct: 984 TPKPGGFHCACPPGF---VGL-RCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT 1039
Query: 184 LRENVCR-DVDECSRPRPVCRNGTCENLPGA---YLCHCDDGFKAGP----NNDCVDVNE 235
C ++D C +P GTCE G+ ++CHC GF+ GP +
Sbjct: 1040 --GQWCEVEIDPC-HSQPCFHGGTCEATAGSPLGFICHCPKGFE-GPTCSHRAPSCGFHH 1095
Query: 236 CREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE---CDELPHPCGRDGNPS 292
C GG+ + + RC C GY G +C C P PC +G S
Sbjct: 1096 CHHGGLCLPSPKPGFPP---RCACLSGY----GGPDCLTPPAPKGCGP-PSPCLYNG--S 1145
Query: 293 CTNTNG----GYECSC 304
C+ T G G+ CSC
Sbjct: 1146 CSETTGLGGPGFRCSC 1161
Score = 96.7 bits (230), Expect = 3e-19
Identities = 119/412 (28%), Positives = 163/412 (39%), Gaps = 91/412 (22%)
Query: 243 CRNG-RCRN-TVGSFRCECAPGYTLTADGRNCRDVDECDE-------------LPHPCGR 287
C NG C + ++G C+CAPG+ G C+ D C LP P G
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFL----GETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 90
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECR-NFNGGYVCECP 345
+PS + + C+C G+ G RC + E P C+ G C +G C C
Sbjct: 91 PSSPSPLTPS--FLCTCLPGF--TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCE-RCPA 404
GW T C + ++ C A P C + G Y + +C
Sbjct: 147 PGW----TGEQC--QLRDFC----------SANP--------CVNGGVCLATYPQIQCHC 182
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDG 463
P E C+ +D++EC P C G C NT GSF+C CP G +G
Sbjct: 183 PPGFE-GHACE---------RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEG 228
Query: 464 LSC-VDADECALDPRICGN-GTC----SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGR 517
C + A C PR C N GTC + C C PGF GPD V+ D C +
Sbjct: 229 PRCELRAGPC--PPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI-GPDCE-VNPDNCVSHQ 284
Query: 518 ASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDEC-VQEPRVCPH--ACENVVGSYI 573
C + ++ C CP + G C D+DEC Q P C + C+N GS+
Sbjct: 285 CQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
C C G+ TS E++++C G CI+ GSF C C G
Sbjct: 341 CVCVSGWGGTSCE-------ENLDDC-IAATCAPGSTCIDRVGSFSCLCPPG 384
Score = 94.3 bits (224), Expect = 2e-18
Identities = 130/513 (25%), Positives = 177/513 (34%), Gaps = 80/513 (15%)
Query: 380 LQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG 439
L L + C C+ G E C PD + ++CQ G L P
Sbjct: 44 LSLGQGTCQCAPGFLG----ETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 99
Query: 440 GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGN-GTCS-NTRGGYECQCSP 497
SF C C G+ G C E P C G C G +C C P
Sbjct: 100 --------SFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMP 147
Query: 498 GFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQ 556
G+T + C D C+ C T +C CP G+ +G C RD++EC Q
Sbjct: 148 GWT---GEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQ 200
Query: 557 EPRVCPH--ACENVVGSYICKCP---EGYR-RTSAPQDSENACEDINECEEQEDLCSG-G 609
+P CP +C N +GS+ C CP EG R A C + C+ + S
Sbjct: 201 DPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFH 260
Query: 610 VCINTDGSFLCDCDAGFE-----PSEDGTDC---IDRRTGTCYRSLVSGRCEPEXXXXXX 661
+C+ G DC+ + ++G C +D T C + C +
Sbjct: 261 LCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECET 320
Query: 662 XXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWG-SECELCPAPGSPARLDLCTAVNLTPX 720
G C C G WG + CE LD C A P
Sbjct: 321 QGPPHCRNGGTCQNSAGSF---HCVCVSG--WGGTSCE--------ENLDDCIAATCAPG 367
Query: 721 XXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP----GLCAP----GRFRCVCGPGYR 772
L D+ C + P C+ G C+C PGY
Sbjct: 368 STCIDRVGSFSCLCPPGRTGLLCHLEDM--CLSQPCHGDAQCSTNPLTGSTLCLCQPGY- 424
Query: 773 PAGEVC-ADVDECAVR---PPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR-DVDEC 825
+G C D+DEC + P PC+ C NT GS++CLC GY G+ C D +EC
Sbjct: 425 -SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNEC 479
Query: 826 ERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
C + ++ C C G E G C
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLE--GQLC 510
Score = 77.4 bits (182), Expect = 2e-13
Identities = 113/396 (28%), Positives = 139/396 (35%), Gaps = 79/396 (19%)
Query: 21 YLCCCSVGHAWGAPCE--ACPPRGSPAHT-ALCGEKPGEYINPVT------NETKPIDEC 71
Y C C G G+ C+ P P A C +P Y+ N +K +D C
Sbjct: 914 YFCHCPPGFQ-GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDAC 972
Query: 72 DIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCR--GMAQCV 127
P C GTC P GF C C G+ C DVDEC PC G A C
Sbjct: 973 QSQP--CHNHGTCTPKPGGFHCACPPGF----VGLRCEGDVDECL--DQPCHPTGTAACH 1024
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGS---YRCECKPGYTL 184
+L AF C+C PG+ T E E +D C Q G C T GS + C C G+
Sbjct: 1025 SLANAFYCQCLPGH--TGQWCEVE-IDPCHSQPCFHGGTCEATAGSPLGFICHCPKGF-- 1079
Query: 185 RENVCRDVDECSRPRPVC------RNGTCENLPGAYL---CHCDDGFKAGPNNDCVDV-- 233
+ CS P C G C P C C G+ GP DC+
Sbjct: 1080 ------EGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGY-GGP--DCLTPPA 1130
Query: 234 -NECREGGMVCRNGRCRNTVG----SFRCEC---APGYTLTADG-RNCRDVDECDELPHP 284
C NG C T G FRC C +PG G + C
Sbjct: 1131 PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAG 1190
Query: 285 CGRDGNPSCTNTNGGYECSCGAG--WKLVGR--RCVDRDECKELPYVCAGGECRNFNGGY 340
C G N +GG +CS G WK RC + C EC F+G Y
Sbjct: 1191 CSGPGG----NWDGG-DCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECL-FDG-Y 1243
Query: 341 VCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHR 376
CE P C + C+D + G C +
Sbjct: 1244 DCETPPA---------CTPAYDQYCHDHFHNGHCEK 1270
Score = 71.7 bits (168), Expect = 1e-11
Identities = 108/408 (26%), Positives = 142/408 (34%), Gaps = 80/408 (19%)
Query: 472 CALDPRICGNG-TC-SNTRGGYECQCSPGF----TQGPDQTCVDVDECAEGRASCTFRCH 525
C P C NG TC S + G CQC+PGF Q PD C + C G SC
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNG-GSCQALLP 85
Query: 526 NTAG----------SFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH--ACE-NVVGSY 572
G SF CTC G+ G C+ E P C C G
Sbjct: 86 APLGLPSSPSPLTPSFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRP 141
Query: 573 ICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDG 632
C C G+ T + C N C +GGVC+ T C C GFE G
Sbjct: 142 QCSCMPGW--TGEQCQLRDFC-SANPC------VNGGVCLATYPQIQCHCPPGFE----G 188
Query: 633 TDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAA 692
C +R C++ G C P+ +A C G +
Sbjct: 189 HAC-ERDVNECFQD--PGPC-PKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCS 244
Query: 693 WGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECA 752
G C+L P S L LC + P D + D C
Sbjct: 245 NGGTCQLMPEKDSTFHLCLCPPGFIGP-----------------------DCEVNPDNCV 281
Query: 753 AIP----GLCAPG--RFRCVCGPGYRPAGEVCADVDECAVR-PPPCDQ--LCHNTDGSYD 803
+ G C G + C+C P + DVDEC + PP C C N+ GS+
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLC-PETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340
Query: 804 CLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDG 850
C+C +G+ G +C + +D+C T C + GS+ C C G
Sbjct: 341 CVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG 384
Score = 62.5 bits (145), Expect = 6e-09
Identities = 39/111 (35%), Positives = 53/111 (47%), Gaps = 14/111 (12%)
Query: 747 DVDECAAIP----GLCA--PGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D+DEC + P G C PG F C C PG+ G C +VDEC P P C +
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFE--GPRCQTEVDECLSDPCPVGASCLDLP 608
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
G++ CLC +G+ G C +V C + +QIC + + C C DG
Sbjct: 609 GAFFCLCPSGF----TGQLC-EVPLCAPNLCQPKQICKDQKDKANCLCPDG 654
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 18/117 (15%)
Query: 746 ADVDECAAIPGLCAPGR--------FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCH 796
AD +EC + P C PG F C+C PG G++C + +ECA P CH
Sbjct: 474 ADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE--GQLCEVETNECASAPCLNHADCH 529
Query: 797 NTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+ + C+C G+ G C D+DEC C + G++ C C G+E
Sbjct: 530 DLLNGFQCICLPGFS----GTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE 582
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/113 (31%), Positives = 54/113 (47%), Gaps = 14/113 (12%)
Query: 747 DVDECAAIPGL----CAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+ +ECA+ P L C F+C+C PG+ +G C D+DEC P C +
Sbjct: 513 ETNECASAPCLNHADCHDLLNGFQCICLPGF--SGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G++ C C G+E G C+ +VDEC D C + G++ C C G+
Sbjct: 571 GAFHCKCLPGFE----GPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGF 619
Score = 54.4 bits (125), Expect = 2e-06
Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 10/109 (9%)
Query: 747 DVDECAAIPGLCAPG--RFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYD 803
DV GLC + C C PG++ G +C D V+ C RP C Y
Sbjct: 896 DVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHVNPCESRPCQNGATCMAQPSGYL 953
Query: 804 CLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C C GY DG NC +++D C+ C+ G + C+C G+
Sbjct: 954 CQCAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGF 998
Score = 48.4 bits (110), Expect = 1e-04
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 8/97 (8%)
Query: 757 LCAPGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 815
L PG F C+C PGY G C AD +EC +P C + ++ CLC G E
Sbjct: 453 LNTPGSFNCLCPPGY--TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE---- 506
Query: 816 GANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C + +EC C + ++C C G+
Sbjct: 507 GQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 543
Score = 42.3 bits (95), Expect = 0.007
Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 10/101 (9%)
Query: 749 DECAAIPGLCAPGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCR 807
D C G C R CVC G+ G C A++ C P C+ Y+C C
Sbjct: 663 DNCTCHHGHCQ--RSSCVCDVGW--TGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 718
Query: 808 TGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSC 847
TGY G C ++ C C+ + G Y C+C
Sbjct: 719 TGY----TGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 755
Score = 40.3 bits (90), Expect = 0.028
Identities = 33/124 (26%), Positives = 48/124 (38%), Gaps = 18/124 (14%)
Query: 746 ADVDECAAIP----GLC--APGRFRCVCGPGYRPAGEVCADVDECAVRPPPC--DQLCHN 797
A++ C + P G C P + C C GY G C++ + A PC C+
Sbjct: 690 AELGGCISAPCAHGGTCYPQPSGYNCTCPTGY--TGPTCSE-EMTACHSGPCLNGGSCNP 746
Query: 798 TDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
+ G Y C C + G C+ D C C N G++ C C G++ G
Sbjct: 747 SPGGYYCTCPPSHT----GPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQ--GP 800
Query: 857 ACVG 860
C G
Sbjct: 801 RCEG 804
Score = 36.7 bits (81), Expect = 0.35
Identities = 23/78 (29%), Positives = 31/78 (39%), Gaps = 5/78 (6%)
Query: 759 APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
+PG + C C P + G C D C P C N G++ CLC G++
Sbjct: 747 SPGGYYCTCPPSH--TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEG 804
Query: 818 NCRD--VDECERDTHTCQ 833
R D R+ TCQ
Sbjct: 805 KLRPSCADSPCRNRATCQ 822
Score = 36.7 bits (81), Expect = 0.35
Identities = 29/106 (27%), Positives = 44/106 (41%), Gaps = 18/106 (16%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DV 822
RC+C P G +D CA +P P + C T S+ CLC G+ G C +
Sbjct: 829 RCLC-PTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGW----TGPLCNLPL 883
Query: 823 DECERD--------THTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
C++ + C +C ++ SY C C G++ G C
Sbjct: 884 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLC 927
Score = 35.1 bits (77), Expect = 1.1
Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 14/73 (19%)
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDG 850
LC ++ SY C C G++ G+ C+D V+ CE + CQ C Y C C G
Sbjct: 906 LCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPG 959
Query: 851 YE-----KRGDAC 858
Y+ K DAC
Sbjct: 960 YDGQNCSKELDAC 972
>AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein.
Length = 1238
Score = 189 bits (461), Expect = 3e-47
Identities = 177/632 (28%), Positives = 255/632 (40%), Gaps = 88/632 (13%)
Query: 23 CCCSVGHAW-GAPCEACPPRGSPAHTALCGEKPGEYINPVTNE-----TKPIDECDIMPQ 76
C CS G W G C+ C P H + C E P + N TN K ++ C
Sbjct: 262 CRCSYG--WQGRFCDECVPYPGCVHGS-CVE-PWQ-CNCETNWGGLLCDKDLNYCGSHHP 316
Query: 77 LCKPGTCHDT-PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC 135
GTC + P ++C C GY N C + P C C +P FEC
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRN----CEKAEHACTSNP-CANGGSCHEVPSGFEC 371
Query: 136 RCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDE 194
CP G+ S C D+DEC G C + + + C C P + D +E
Sbjct: 372 HCPSGW----SGPTCALDIDECASNPCAAGGTCVDQVDGFECIC-PEQWVGATCQLDANE 426
Query: 195 CSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGS 254
C +P +C+NL G Y C C G+K N ++VN+CR G G C++ V
Sbjct: 427 CEG-KPCLNAFSCKNLIGGYYCDCIPGWKG--INCHINVNDCR--GQCQHGGTCKDLVNG 481
Query: 255 FRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR 313
++C C G+ GR+C + DEC PC G C + G+ C C G+ G
Sbjct: 482 YQCVCPRGF----GGRHCELERDECAS--SPCHSGG--LCEDLADGFHCHCPQGFS--GP 531
Query: 314 RC-VDRDECKELPYVCAGG-ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEA 371
C VD D C+ P C G C N G Y C CP + K +V +E C
Sbjct: 532 LCEVDVDLCEPSP--CRNGARCYNLEGDYYCACPDDFG-GKNCSV----PREPC----PG 580
Query: 372 GRCHRARPLQLARPECCCS-EGAAWGRYCE---RCPAPDSAEFMRICQGGMGRPNLTQDL 427
G C R + + G A C RC + F IC G +++
Sbjct: 581 GAC---RVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENI 637
Query: 428 DECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRIC-GNGTC 484
D+C +P C GG C++ +FRC CP G+ +G C + ++C DP C G C
Sbjct: 638 DDCLGQP--CRNGGTCIDEVDAFRCFCPSGW----EGELCDTNPNDCLPDP--CHSRGRC 689
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVD-ECAEGRASCTFRCHNTAGSFRCTCPYGYAVAA 543
+ + C C G+ +TC + +C S C+++ +FRC CP G+ +
Sbjct: 690 YDLVNDFYCACDDGWK---GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGST 746
Query: 544 DGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQE 603
V C+ P V C S+ C C +G+ + + N+C
Sbjct: 747 CAVAKNS--SCLPNPCVNGGTCVGSGASFSCICRDGW-------EGRTCTHNTNDCNPLP 797
Query: 604 DLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
+GG+C++ F C+C GF G DC
Sbjct: 798 -CYNGGICVDGVNWFRCECAPGFA----GPDC 824
Score = 177 bits (432), Expect = 1e-43
Identities = 186/625 (29%), Positives = 259/625 (41%), Gaps = 112/625 (17%)
Query: 20 KYLCCCSVGHAWGAPCE----ACPPR----GSPAHTALCGEK---PGEYINPVTNETKPI 68
+Y C C G++ G CE AC G H G + P + P I
Sbjct: 330 QYRCTCPDGYS-GRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTC--ALDI 386
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC P GTC D GF+C C + T L D +EC G+P C C N
Sbjct: 387 DECASNP-CAAGGTCVDQVDGFECICPEQWV-GATCQL--DANECE-GKP-CLNAFSCKN 440
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD-CRNTIGSYRCECKPGYTLREN 187
L G + C C PG++ ++ +V++C Q C HG C++ + Y+C C G+ R
Sbjct: 441 LIGGYYCDCIPGWK---GINCHINVNDCRGQ--CQHGGTCKDLVNGYQCVCPRGFGGRH- 494
Query: 188 VCR-DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
C + DEC+ P G CE+L + CHC GF +GP + VDV+ C CRNG
Sbjct: 495 -CELERDECASS-PCHSGGLCEDLADGFHCHCPQGF-SGPLCE-VDVDLCEPSP--CRNG 548
Query: 247 -RCRNTVGSFRCECAPGY--------TLTADGRNCRDVDECDELPHP----------CGR 287
RC N G + C C + G CR +D C P CG
Sbjct: 549 ARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGP 608
Query: 288 DGNPSCTNTNGG-YECSCGAGWKLVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCEC 344
G C + GG + C C +G+ G C + D+C P C GG C + + C C
Sbjct: 609 HGR--CVSQPGGNFSCICDSGF--TGTYCHENIDDCLGQP--CRNGGTCIDEVDAFRCFC 662
Query: 345 PAGWRFDKTAAVCVDERKELCYDEWEAGRCH-RARPLQLARP-ECCCSEGAAW-GRYCE- 400
P+GW + +C D C + CH R R L C C +G W G+ C
Sbjct: 663 PSGWEGE----LC-DTNPNDCLPD----PCHSRGRCYDLVNDFYCACDDG--WKGKTCHS 711
Query: 401 ---RCPAP---------DSAEFMRIC--QGGMGRPNLTQDLDECRVRPDVCV-GGRCVNT 445
+C A DS + R G G C P+ CV GG CV +
Sbjct: 712 REFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCL--PNPCVNGGTCVGS 769
Query: 446 DGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGP 503
SF C C DG+ +G +C + ++C +P C NG C + + C+C+PGF GP
Sbjct: 770 GASFSCICRDGW----EGRTCTHNTNDC--NPLPCYNGGICVDGVNWFRCECAPGFA-GP 822
Query: 504 DQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI----DECVQEPR 559
D +++DEC + C + +RC+CP G A G C+++ C
Sbjct: 823 DCR-INIDECQSSPCAYGATCVDEINGYRCSCPPGRA----GPRCQEVIGFGRSCWSRGT 877
Query: 560 VCPHACENVVGSYICKCPEGYRRTS 584
PH V C+C +G R S
Sbjct: 878 PFPHGSSWVEDCNSCRCLDGRRDCS 902
Score = 155 bits (375), Expect = 8e-37
Identities = 155/562 (27%), Positives = 226/562 (40%), Gaps = 101/562 (17%)
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDE----CE-DVDECGDQRICDHGD- 166
CS+G R +CV PG C ++ + C+ D++ CG C +G
Sbjct: 264 CSYGWQG-RFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGT 322
Query: 167 CRNTI-GSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG 225
C N YRC C GY+ R C + P G+C +P + CHC G+ +G
Sbjct: 323 CINAEPDQYRCTCPDGYSGRN--CEKAEHACTSNPCANGGSCHEVPSGFECHCPSGW-SG 379
Query: 226 PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHP 284
P +D++EC G C + V F C C + G C+ D +EC+ P
Sbjct: 380 P-TCALDIDECASNPCAA-GGTCVDQVDGFECICPEQWV----GATCQLDANECE--GKP 431
Query: 285 CGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCE 343
C SC N GGY C C GWK G C ++ ++C+ GG C++ GY C
Sbjct: 432 CLNAF--SCKNLIGGYYCDCIPGWK--GINCHINVNDCR--GQCQHGGTCKDLVNGYQCV 485
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
CP G+ C ER DE + CH C E A G +C CP
Sbjct: 486 CPRGF----GGRHCELER-----DECASSPCHSG--------GLC--EDLADGFHC-HCP 525
Query: 404 APDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGY----V 458
QG G P D+D C P C G RC N +G + C CPD +
Sbjct: 526 -----------QGFSG-PLCEVDVDLC--EPSPCRNGARCYNLEGDYYCACPDDFGGKNC 571
Query: 459 LAP----DGLSCVDADECALD----------PRICG-NGTCSNTRGG-YECQCSPGFTQG 502
P G +C D C D +CG +G C + GG + C C GFT
Sbjct: 572 SVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFT-- 629
Query: 503 PDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVC 561
++D+C C + +FRC CP G+ +G C + ++C+ +P
Sbjct: 630 GTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGW----EGELCDTNPNDCLPDPCHS 685
Query: 562 PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCD 621
C ++V + C C +G++ + E C D C +GG C ++ +F C
Sbjct: 686 RGRCYDLVNDFYCACDDGWKGKTC-HSREFQC-DAYTCS------NGGTCYDSGDTFRCA 737
Query: 622 CDAGFEPSEDGTDCIDRRTGTC 643
C G++ G+ C + +C
Sbjct: 738 CPPGWK----GSTCAVAKNSSC 755
Score = 118 bits (283), Expect = 1e-25
Identities = 81/255 (31%), Positives = 117/255 (45%), Gaps = 39/255 (15%)
Query: 386 ECCCSEGAAW-GRYCERC-PAPDSAEFMRI------CQGGMGRPNLTQDLDECRVRPDVC 437
EC CS G W GR+C+ C P P + C+ G +DL+ C
Sbjct: 261 ECRCSYG--WQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCT 318
Query: 438 VGGRCVNTD-GSFRCECPDGYVLAPDGLSCVDADE-CALDPRICGNG-TCSNTRGGYECQ 494
GG C+N + +RC CPDGY G +C A+ C +P C NG +C G+EC
Sbjct: 319 NGGTCINAEPDQYRCTCPDGY----SGRNCEKAEHACTSNP--CANGGSCHEVPSGFECH 372
Query: 495 CSPGFTQGPDQTC-VDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DID 552
C G++ GP TC +D+DECA + C + F C CP + G C+ D +
Sbjct: 373 CPSGWS-GP--TCALDIDECASNPCAAGGTCVDQVDGFECICPEQWV----GATCQLDAN 425
Query: 553 ECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCS-GGVC 611
EC +P + +C+N++G Y C C G++ N ++N+C Q C GG C
Sbjct: 426 ECEGKPCLNAFSCKNLIGGYYCDCIPGWK-------GINCHINVNDCRGQ---CQHGGTC 475
Query: 612 INTDGSFLCDCDAGF 626
+ + C C GF
Sbjct: 476 KDLVNGYQCVCPRGF 490
Score = 109 bits (261), Expect = 5e-23
Identities = 97/342 (28%), Positives = 144/342 (42%), Gaps = 49/342 (14%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
ID+C + Q C+ G TC D F+C C G+E + LC D + PC +C
Sbjct: 637 IDDC--LGQPCRNGGTCIDEVDAFRCFCPSGWEGE----LC-DTNPNDCLPDPCHSRGRC 689
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD-CRNTIGSYRCECKPGYTLR 185
+L F C C G++ C + D C +G C ++ ++RC C PG+ +
Sbjct: 690 YDLVNDFYCACDDGWKGKT----CHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGW--K 743
Query: 186 ENVCRDVDECS-RPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCV-DVNECREGGMVC 243
+ C S P P GTC ++ C C DG++ C + N+C + C
Sbjct: 744 GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEG---RTCTHNTNDCNP--LPC 798
Query: 244 RNGR-CRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYE 301
NG C + V FRCECAPG+ G +CR ++DEC P G +C + GY
Sbjct: 799 YNGGICVDGVNWFRCECAPGFA----GPDCRINIDECQSSPCAYG----ATCVDEINGYR 850
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER 361
CSC G G RC + + G C ++ G + W D + C+D R
Sbjct: 851 CSCPPG--RAGPRCQE--------VIGFGRSC--WSRGTPFPHGSSWVEDCNSCRCLDGR 898
Query: 362 KELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
++ C W C L +PE ++ R E+ P
Sbjct: 899 RD-CSKVW----CGWKPCLLAGQPEALSAQCPLGQRCLEKAP 935
Score = 54.0 bits (124), Expect = 2e-06
Identities = 31/95 (32%), Positives = 43/95 (45%), Gaps = 8/95 (8%)
Query: 760 PGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
P F C C G+ +G CA D+DECA P C + ++C+C + GA
Sbjct: 366 PSGFECHCPSGW--SGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWV----GAT 419
Query: 819 CR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
C+ D +ECE C N G Y C C G++
Sbjct: 420 CQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWK 454
Score = 48.4 bits (110), Expect = 1e-04
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 8/92 (8%)
Query: 760 PGRFRCVCGPGYRPAGEVCADVDE-CAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
P ++RC C GY +G C + C P CH ++C C +G+ G
Sbjct: 328 PDQYRCTCPDGY--SGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGW----SGPT 381
Query: 819 CR-DVDECERDTHTCQQICSNTEGSYECSCED 849
C D+DEC + C + +EC C +
Sbjct: 382 CALDIDECASNPCAAGGTCVDQVDGFECICPE 413
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 9/92 (9%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC- 819
FRC C PG++ G CA + P PC C + S+ C+CR G+E G C
Sbjct: 734 FRCACPPGWK--GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWE----GRTCT 787
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
+ ++C IC + + C C G+
Sbjct: 788 HNTNDCNPLPCYNGGICVDGVNWFRCECAPGF 819
Score = 46.4 bits (105), Expect = 4e-04
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 12/109 (11%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C + PG G F C+C G+ G C + +D+C +P C + ++ C C +G
Sbjct: 612 CVSQPG----GNFSCICDSGF--TGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSG 665
Query: 810 YELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
+E + N D C D + C + + C+C+DG+ +G C
Sbjct: 666 WEGELCDTNPND---CLPDPCHSRGRCYDLVNDFYCACDDGW--KGKTC 709
Score = 42.7 bits (96), Expect = 0.005
Identities = 41/134 (30%), Positives = 56/134 (41%), Gaps = 36/134 (26%)
Query: 749 DECAAIP----GLC---APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQ--LCHNT 798
DECA+ P GLC A G F C C G+ +G +C DVD C P PC C+N
Sbjct: 500 DECASSPCHSGGLCEDLADG-FHCHCPQGF--SGPLCEVDVDLC--EPSPCRNGARCYNL 554
Query: 799 DGSYDCLCRTGY-----ELDED---GANCRDVDECERDT------HTCQQIC-------S 837
+G Y C C + + + G CR +D C D +C S
Sbjct: 555 EGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVS 614
Query: 838 NTEGSYECSCEDGY 851
G++ C C+ G+
Sbjct: 615 QPGGNFSCICDSGF 628
Score = 41.9 bits (94), Expect = 0.009
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 14/100 (14%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC 819
F C+C G+ G C + ++C P PC +C + + C C G+ G +C
Sbjct: 773 FSCICRDGWE--GRTCTHNTNDC--NPLPCYNGGICVDGVNWFRCECAPGFA----GPDC 824
Query: 820 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
R ++DEC+ C + Y CSC G + G C
Sbjct: 825 RINIDECQSSPCAYGATCVDEINGYRCSCPPG--RAGPRC 862
Score = 35.9 bits (79), Expect = 0.61
Identities = 22/95 (23%), Positives = 39/95 (41%), Gaps = 9/95 (9%)
Query: 763 FRCVCGPGYRPAGEVCADVD-ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 821
F C C G++ G+ C + +C C+++ ++ C C G++ G+ C
Sbjct: 696 FYCACDDGWK--GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWK----GSTCAV 749
Query: 822 VDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKR 854
+ C C + S+ C C DG+E R
Sbjct: 750 AKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGR 784
Score = 35.1 bits (77), Expect = 1.1
Identities = 34/109 (31%), Positives = 41/109 (37%), Gaps = 20/109 (18%)
Query: 751 CAAIPGLCA-PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C + G C PG RC Y G C DEC P C + C C T
Sbjct: 249 CNLLHGGCTVPGECRC----SYGWQGRFC---DECVPYPGCVHGSCVEP---WQCNCETN 298
Query: 810 YELDEDGANC-RDVDECERDTHTCQQ--ICSNTE-GSYECSCEDGYEKR 854
+ G C +D++ C H C C N E Y C+C DGY R
Sbjct: 299 W----GGLLCDKDLNYCGSH-HPCTNGGTCINAEPDQYRCTCPDGYSGR 342
>AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein.
Length = 1238
Score = 188 bits (458), Expect = 7e-47
Identities = 176/632 (27%), Positives = 256/632 (40%), Gaps = 88/632 (13%)
Query: 23 CCCSVGHAW-GAPCEACPPRGSPAHTALCGEKPGEYINPVTNE-----TKPIDECDIMPQ 76
C CS G W G C+ C P H + C E P + N TN K ++ C
Sbjct: 262 CRCSYG--WQGRFCDECVPYPGCVHGS-CVE-PWQ-CNCETNWGGLLCDKDLNYCGSHHP 316
Query: 77 LCKPGTCHDT-PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC 135
GTC + P ++C C GY N C + P C C +P FEC
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRN----CEKAEHACTSNP-CANGGSCHEVPSGFEC 371
Query: 136 RCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDE 194
CP G+ S C D+DEC G C + + + C C P + DV++
Sbjct: 372 HCPSGW----SGPTCALDIDECASNPCAAGGTCVDQVDGFECIC-PEQWVGATCQLDVND 426
Query: 195 CSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGS 254
C +P +C+NL G Y C C G+K N ++VN+CR G G C++ V
Sbjct: 427 CEG-KPCLNAFSCKNLIGGYYCDCIPGWKG--INCHINVNDCR--GQCQHGGTCKDLVNG 481
Query: 255 FRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR 313
++C C G+ GR+C + D+C PC G C + G+ C C G+ G
Sbjct: 482 YQCVCPRGF----GGRHCELERDKCAS--SPCHSGG--LCEDLADGFHCHCPQGFS--GP 531
Query: 314 RC-VDRDECKELPYVCAGG-ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEA 371
C VD D C+ P C G C N G Y C CP + K +V +E C
Sbjct: 532 LCEVDVDLCEPSP--CRNGARCYNLEGDYYCACPDDFG-GKNCSV----PREPC----PG 580
Query: 372 GRCHRARPLQLARPECCCS-EGAAWGRYCE---RCPAPDSAEFMRICQGGMGRPNLTQDL 427
G C R + + G A C RC + F IC G +++
Sbjct: 581 GAC---RVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENI 637
Query: 428 DECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRIC-GNGTC 484
D+C +P C GG C++ +FRC CP G+ +G C + ++C DP C G C
Sbjct: 638 DDCLGQP--CRNGGTCIDEVDAFRCFCPSGW----EGELCDTNPNDCLPDP--CHSRGRC 689
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVD-ECAEGRASCTFRCHNTAGSFRCTCPYGYAVAA 543
+ + C C G+ +TC + +C S C+++ +FRC CP G+ +
Sbjct: 690 YDLVNDFYCACDDGWK---GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGST 746
Query: 544 DGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQE 603
V C+ P V C S+ C C +G+ + + N+C
Sbjct: 747 CAVAKNS--SCLPNPCVNGGTCVGSGASFSCICRDGW-------EGRTCTHNTNDCNPLP 797
Query: 604 DLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
+GG+C++ F C+C GF G DC
Sbjct: 798 -CYNGGICVDGVNWFRCECAPGFA----GPDC 824
Score = 176 bits (429), Expect = 2e-43
Identities = 185/625 (29%), Positives = 260/625 (41%), Gaps = 112/625 (17%)
Query: 20 KYLCCCSVGHAWGAPCE----ACPPR----GSPAHTALCGEK---PGEYINPVTNETKPI 68
+Y C C G++ G CE AC G H G + P + P I
Sbjct: 330 QYRCTCPDGYS-GRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTC--ALDI 386
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC P GTC D GF+C C + T L DV++C G+P C C N
Sbjct: 387 DECASNP-CAAGGTCVDQVDGFECICPEQWV-GATCQL--DVNDCE-GKP-CLNAFSCKN 440
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD-CRNTIGSYRCECKPGYTLREN 187
L G + C C PG++ ++ +V++C Q C HG C++ + Y+C C G+ R
Sbjct: 441 LIGGYYCDCIPGWK---GINCHINVNDCRGQ--CQHGGTCKDLVNGYQCVCPRGFGGRH- 494
Query: 188 VCR-DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
C + D+C+ P G CE+L + CHC GF +GP + VDV+ C CRNG
Sbjct: 495 -CELERDKCASS-PCHSGGLCEDLADGFHCHCPQGF-SGPLCE-VDVDLCEPSP--CRNG 548
Query: 247 -RCRNTVGSFRCECAPGY--------TLTADGRNCRDVDECDELPHP----------CGR 287
RC N G + C C + G CR +D C P CG
Sbjct: 549 ARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGP 608
Query: 288 DGNPSCTNTNGG-YECSCGAGWKLVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCEC 344
G C + GG + C C +G+ G C + D+C P C GG C + + C C
Sbjct: 609 HGR--CVSQPGGNFSCICDSGF--TGTYCHENIDDCLGQP--CRNGGTCIDEVDAFRCFC 662
Query: 345 PAGWRFDKTAAVCVDERKELCYDEWEAGRCH-RARPLQLARP-ECCCSEGAAW-GRYCE- 400
P+GW + +C D C + CH R R L C C +G W G+ C
Sbjct: 663 PSGWEGE----LC-DTNPNDCLPD----PCHSRGRCYDLVNDFYCACDDG--WKGKTCHS 711
Query: 401 ---RCPAP---------DSAEFMRIC--QGGMGRPNLTQDLDECRVRPDVCV-GGRCVNT 445
+C A DS + R G G C P+ CV GG CV +
Sbjct: 712 REFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCL--PNPCVNGGTCVGS 769
Query: 446 DGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGP 503
SF C C DG+ +G +C + ++C +P C NG C + + C+C+PGF GP
Sbjct: 770 GASFSCICRDGW----EGRTCTHNTNDC--NPLPCYNGGICVDGVNWFRCECAPGFA-GP 822
Query: 504 DQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI----DECVQEPR 559
D +++DEC + C + +RC+CP G A G C+++ C
Sbjct: 823 DCR-INIDECQSSPCAYGATCVDEINGYRCSCPPGRA----GPRCQEVIGFGRSCWSRGT 877
Query: 560 VCPHACENVVGSYICKCPEGYRRTS 584
PH V C+C +G R S
Sbjct: 878 PFPHGSSWVEDCNSCRCLDGRRDCS 902
Score = 153 bits (372), Expect = 2e-36
Identities = 154/562 (27%), Positives = 227/562 (40%), Gaps = 101/562 (17%)
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDE----CE-DVDECGDQRICDHGD- 166
CS+G R +CV PG C ++ + C+ D++ CG C +G
Sbjct: 264 CSYGWQG-RFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGT 322
Query: 167 CRNTI-GSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG 225
C N YRC C GY+ R C + P G+C +P + CHC G+ +G
Sbjct: 323 CINAEPDQYRCTCPDGYSGRN--CEKAEHACTSNPCANGGSCHEVPSGFECHCPSGW-SG 379
Query: 226 PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHP 284
P +D++EC G C + V F C C + G C+ DV++C+ P
Sbjct: 380 P-TCALDIDECASNPCAA-GGTCVDQVDGFECICPEQWV----GATCQLDVNDCE--GKP 431
Query: 285 CGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCE 343
C SC N GGY C C GWK G C ++ ++C+ GG C++ GY C
Sbjct: 432 CLNAF--SCKNLIGGYYCDCIPGWK--GINCHINVNDCR--GQCQHGGTCKDLVNGYQCV 485
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
CP G+ C ER D+ + CH C E A G +C CP
Sbjct: 486 CPRGF----GGRHCELER-----DKCASSPCHSG--------GLC--EDLADGFHC-HCP 525
Query: 404 APDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGY----V 458
QG G P D+D C P C G RC N +G + C CPD +
Sbjct: 526 -----------QGFSG-PLCEVDVDLC--EPSPCRNGARCYNLEGDYYCACPDDFGGKNC 571
Query: 459 LAP----DGLSCVDADECALD----------PRICG-NGTCSNTRGG-YECQCSPGFTQG 502
P G +C D C D +CG +G C + GG + C C GFT
Sbjct: 572 SVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFT-- 629
Query: 503 PDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVC 561
++D+C C + +FRC CP G+ +G C + ++C+ +P
Sbjct: 630 GTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGW----EGELCDTNPNDCLPDPCHS 685
Query: 562 PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCD 621
C ++V + C C +G++ + E C D C +GG C ++ +F C
Sbjct: 686 RGRCYDLVNDFYCACDDGWKGKTC-HSREFQC-DAYTCS------NGGTCYDSGDTFRCA 737
Query: 622 CDAGFEPSEDGTDCIDRRTGTC 643
C G++ G+ C + +C
Sbjct: 738 CPPGWK----GSTCAVAKNSSC 755
Score = 118 bits (284), Expect = 9e-26
Identities = 80/255 (31%), Positives = 118/255 (46%), Gaps = 39/255 (15%)
Query: 386 ECCCSEGAAW-GRYCERC-PAPDSAEFMRI------CQGGMGRPNLTQDLDECRVRPDVC 437
EC CS G W GR+C+ C P P + C+ G +DL+ C
Sbjct: 261 ECRCSYG--WQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCT 318
Query: 438 VGGRCVNTD-GSFRCECPDGYVLAPDGLSCVDADE-CALDPRICGNG-TCSNTRGGYECQ 494
GG C+N + +RC CPDGY G +C A+ C +P C NG +C G+EC
Sbjct: 319 NGGTCINAEPDQYRCTCPDGY----SGRNCEKAEHACTSNP--CANGGSCHEVPSGFECH 372
Query: 495 CSPGFTQGPDQTC-VDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DID 552
C G++ GP TC +D+DECA + C + F C CP + G C+ D++
Sbjct: 373 CPSGWS-GP--TCALDIDECASNPCAAGGTCVDQVDGFECICPEQWV----GATCQLDVN 425
Query: 553 ECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCS-GGVC 611
+C +P + +C+N++G Y C C G++ N ++N+C Q C GG C
Sbjct: 426 DCEGKPCLNAFSCKNLIGGYYCDCIPGWK-------GINCHINVNDCRGQ---CQHGGTC 475
Query: 612 INTDGSFLCDCDAGF 626
+ + C C GF
Sbjct: 476 KDLVNGYQCVCPRGF 490
Score = 109 bits (261), Expect = 5e-23
Identities = 97/342 (28%), Positives = 144/342 (42%), Gaps = 49/342 (14%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
ID+C + Q C+ G TC D F+C C G+E + LC D + PC +C
Sbjct: 637 IDDC--LGQPCRNGGTCIDEVDAFRCFCPSGWEGE----LC-DTNPNDCLPDPCHSRGRC 689
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD-CRNTIGSYRCECKPGYTLR 185
+L F C C G++ C + D C +G C ++ ++RC C PG+ +
Sbjct: 690 YDLVNDFYCACDDGWKGKT----CHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGW--K 743
Query: 186 ENVCRDVDECS-RPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCV-DVNECREGGMVC 243
+ C S P P GTC ++ C C DG++ C + N+C + C
Sbjct: 744 GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEG---RTCTHNTNDCNP--LPC 798
Query: 244 RNGR-CRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYE 301
NG C + V FRCECAPG+ G +CR ++DEC P G +C + GY
Sbjct: 799 YNGGICVDGVNWFRCECAPGFA----GPDCRINIDECQSSPCAYG----ATCVDEINGYR 850
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER 361
CSC G G RC + + G C ++ G + W D + C+D R
Sbjct: 851 CSCPPG--RAGPRCQE--------VIGFGRSC--WSRGTPFPHGSSWVEDCNSCRCLDGR 898
Query: 362 KELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
++ C W C L +PE ++ R E+ P
Sbjct: 899 RD-CSKVW----CGWKPCLLAGQPEALSAQCPLGQRCLEKAP 935
Score = 54.4 bits (125), Expect = 2e-06
Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 8/95 (8%)
Query: 760 PGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
P F C C G+ +G CA D+DECA P C + ++C+C + GA
Sbjct: 366 PSGFECHCPSGW--SGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWV----GAT 419
Query: 819 CR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
C+ DV++CE C N G Y C C G++
Sbjct: 420 CQLDVNDCEGKPCLNAFSCKNLIGGYYCDCIPGWK 454
Score = 48.4 bits (110), Expect = 1e-04
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 8/92 (8%)
Query: 760 PGRFRCVCGPGYRPAGEVCADVDE-CAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
P ++RC C GY +G C + C P CH ++C C +G+ G
Sbjct: 328 PDQYRCTCPDGY--SGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGW----SGPT 381
Query: 819 CR-DVDECERDTHTCQQICSNTEGSYECSCED 849
C D+DEC + C + +EC C +
Sbjct: 382 CALDIDECASNPCAAGGTCVDQVDGFECICPE 413
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 9/92 (9%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC- 819
FRC C PG++ G CA + P PC C + S+ C+CR G+E G C
Sbjct: 734 FRCACPPGWK--GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWE----GRTCT 787
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
+ ++C IC + + C C G+
Sbjct: 788 HNTNDCNPLPCYNGGICVDGVNWFRCECAPGF 819
Score = 46.4 bits (105), Expect = 4e-04
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 12/109 (11%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C + PG G F C+C G+ G C + +D+C +P C + ++ C C +G
Sbjct: 612 CVSQPG----GNFSCICDSGF--TGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSG 665
Query: 810 YELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
+E + N D C D + C + + C+C+DG+ +G C
Sbjct: 666 WEGELCDTNPND---CLPDPCHSRGRCYDLVNDFYCACDDGW--KGKTC 709
Score = 41.9 bits (94), Expect = 0.009
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 14/100 (14%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC 819
F C+C G+ G C + ++C P PC +C + + C C G+ G +C
Sbjct: 773 FSCICRDGWE--GRTCTHNTNDC--NPLPCYNGGICVDGVNWFRCECAPGFA----GPDC 824
Query: 820 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
R ++DEC+ C + Y CSC G + G C
Sbjct: 825 RINIDECQSSPCAYGATCVDEINGYRCSCPPG--RAGPRC 862
Score = 41.1 bits (92), Expect = 0.016
Identities = 40/134 (29%), Positives = 56/134 (41%), Gaps = 36/134 (26%)
Query: 749 DECAAIP----GLC---APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQ--LCHNT 798
D+CA+ P GLC A G F C C G+ +G +C DVD C P PC C+N
Sbjct: 500 DKCASSPCHSGGLCEDLADG-FHCHCPQGF--SGPLCEVDVDLC--EPSPCRNGARCYNL 554
Query: 799 DGSYDCLCRTGY-----ELDED---GANCRDVDECERDT------HTCQQIC-------S 837
+G Y C C + + + G CR +D C D +C S
Sbjct: 555 EGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVS 614
Query: 838 NTEGSYECSCEDGY 851
G++ C C+ G+
Sbjct: 615 QPGGNFSCICDSGF 628
Score = 35.9 bits (79), Expect = 0.61
Identities = 22/95 (23%), Positives = 39/95 (41%), Gaps = 9/95 (9%)
Query: 763 FRCVCGPGYRPAGEVCADVD-ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 821
F C C G++ G+ C + +C C+++ ++ C C G++ G+ C
Sbjct: 696 FYCACDDGWK--GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWK----GSTCAV 749
Query: 822 VDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKR 854
+ C C + S+ C C DG+E R
Sbjct: 750 AKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGR 784
Score = 35.1 bits (77), Expect = 1.1
Identities = 34/109 (31%), Positives = 41/109 (37%), Gaps = 20/109 (18%)
Query: 751 CAAIPGLCA-PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C + G C PG RC Y G C DEC P C + C C T
Sbjct: 249 CNLLHGGCTVPGECRC----SYGWQGRFC---DECVPYPGCVHGSCVEP---WQCNCETN 298
Query: 810 YELDEDGANC-RDVDECERDTHTCQQ--ICSNTE-GSYECSCEDGYEKR 854
+ G C +D++ C H C C N E Y C+C DGY R
Sbjct: 299 W----GGLLCDKDLNYCGSH-HPCTNGGTCINAEPDQYRCTCPDGYSGR 342
>AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein.
Length = 1238
Score = 188 bits (457), Expect = 1e-46
Identities = 176/632 (27%), Positives = 255/632 (40%), Gaps = 88/632 (13%)
Query: 23 CCCSVGHAW-GAPCEACPPRGSPAHTALCGEKPGEYINPVTNE-----TKPIDECDIMPQ 76
C CS G W G C+ C P H + C E P + N TN K ++ C
Sbjct: 262 CRCSYG--WQGRFCDECVPYPGCVHGS-CVE-PWQ-CNCETNWGGLLCDKDLNYCGSHHP 316
Query: 77 LCKPGTCHDT-PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC 135
GTC + P ++C C GY N C + P C C +P FEC
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRN----CEKAEHACTSNP-CANGGSCHEVPSGFEC 371
Query: 136 RCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDE 194
CP G+ S C D+DEC G C + + + C C P + D +E
Sbjct: 372 HCPSGW----SGPTCALDIDECASNPCAAGGTCVDQVDGFECIC-PEQWVGATCQLDANE 426
Query: 195 CSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGS 254
C +P +C+NL G Y C C G+K N ++VN+CR G G C++ V
Sbjct: 427 CEG-KPCLNAFSCKNLIGGYYCDCIPGWKG--INCHINVNDCR--GQCQHGGTCKDLVNG 481
Query: 255 FRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR 313
++C C G+ GR+C + D+C PC G C + G+ C C G+ G
Sbjct: 482 YQCVCPRGF----GGRHCELERDKCAS--SPCHSGG--LCEDLADGFHCHCPQGFS--GP 531
Query: 314 RC-VDRDECKELPYVCAGG-ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEA 371
C VD D C+ P C G C N G Y C CP + K +V +E C
Sbjct: 532 LCEVDVDLCEPSP--CRNGARCYNLEGDYYCACPDDFG-GKNCSV----PREPC----PG 580
Query: 372 GRCHRARPLQLARPECCCS-EGAAWGRYCE---RCPAPDSAEFMRICQGGMGRPNLTQDL 427
G C R + + G A C RC + F IC G +++
Sbjct: 581 GAC---RVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENI 637
Query: 428 DECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRIC-GNGTC 484
D+C +P C GG C++ +FRC CP G+ +G C + ++C DP C G C
Sbjct: 638 DDCLGQP--CRNGGTCIDEVDAFRCFCPSGW----EGELCDTNPNDCLPDP--CHSRGRC 689
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVD-ECAEGRASCTFRCHNTAGSFRCTCPYGYAVAA 543
+ + C C G+ +TC + +C S C+++ +FRC CP G+ +
Sbjct: 690 YDLVNDFYCACDDGWK---GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGST 746
Query: 544 DGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQE 603
V C+ P V C S+ C C +G+ + + N+C
Sbjct: 747 CAVAKNS--SCLPNPCVNGGTCVGSGASFSCICRDGW-------EGRTCTHNTNDCNPLP 797
Query: 604 DLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
+GG+C++ F C+C GF G DC
Sbjct: 798 -CYNGGICVDGVNWFRCECAPGFA----GPDC 824
Score = 176 bits (428), Expect = 3e-43
Identities = 185/625 (29%), Positives = 259/625 (41%), Gaps = 112/625 (17%)
Query: 20 KYLCCCSVGHAWGAPCE----ACPPR----GSPAHTALCGEK---PGEYINPVTNETKPI 68
+Y C C G++ G CE AC G H G + P + P I
Sbjct: 330 QYRCTCPDGYS-GRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTC--ALDI 386
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC P GTC D GF+C C + T L D +EC G+P C C N
Sbjct: 387 DECASNP-CAAGGTCVDQVDGFECICPEQWV-GATCQL--DANECE-GKP-CLNAFSCKN 440
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD-CRNTIGSYRCECKPGYTLREN 187
L G + C C PG++ ++ +V++C Q C HG C++ + Y+C C G+ R
Sbjct: 441 LIGGYYCDCIPGWK---GINCHINVNDCRGQ--CQHGGTCKDLVNGYQCVCPRGFGGRH- 494
Query: 188 VCR-DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
C + D+C+ P G CE+L + CHC GF +GP + VDV+ C CRNG
Sbjct: 495 -CELERDKCASS-PCHSGGLCEDLADGFHCHCPQGF-SGPLCE-VDVDLCEPSP--CRNG 548
Query: 247 -RCRNTVGSFRCECAPGY--------TLTADGRNCRDVDECDELPHP----------CGR 287
RC N G + C C + G CR +D C P CG
Sbjct: 549 ARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGP 608
Query: 288 DGNPSCTNTNGG-YECSCGAGWKLVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCEC 344
G C + GG + C C +G+ G C + D+C P C GG C + + C C
Sbjct: 609 HGR--CVSQPGGNFSCICDSGF--TGTYCHENIDDCLGQP--CRNGGTCIDEVDAFRCFC 662
Query: 345 PAGWRFDKTAAVCVDERKELCYDEWEAGRCH-RARPLQLARP-ECCCSEGAAW-GRYCE- 400
P+GW + +C D C + CH R R L C C +G W G+ C
Sbjct: 663 PSGWEGE----LC-DTNPNDCLPD----PCHSRGRCYDLVNDFYCACDDG--WKGKTCHS 711
Query: 401 ---RCPAP---------DSAEFMRIC--QGGMGRPNLTQDLDECRVRPDVCV-GGRCVNT 445
+C A DS + R G G C P+ CV GG CV +
Sbjct: 712 REFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCL--PNPCVNGGTCVGS 769
Query: 446 DGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGP 503
SF C C DG+ +G +C + ++C +P C NG C + + C+C+PGF GP
Sbjct: 770 GASFSCICRDGW----EGRTCTHNTNDC--NPLPCYNGGICVDGVNWFRCECAPGFA-GP 822
Query: 504 DQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI----DECVQEPR 559
D +++DEC + C + +RC+CP G A G C+++ C
Sbjct: 823 DCR-INIDECQSSPCAYGATCVDEINGYRCSCPPGRA----GPRCQEVIGFGRSCWSRGT 877
Query: 560 VCPHACENVVGSYICKCPEGYRRTS 584
PH V C+C +G R S
Sbjct: 878 PFPHGSSWVEDCNSCRCLDGRRDCS 902
Score = 153 bits (371), Expect = 3e-36
Identities = 154/562 (27%), Positives = 226/562 (40%), Gaps = 101/562 (17%)
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDE----CE-DVDECGDQRICDHGD- 166
CS+G R +CV PG C ++ + C+ D++ CG C +G
Sbjct: 264 CSYGWQG-RFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGT 322
Query: 167 CRNTI-GSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG 225
C N YRC C GY+ R C + P G+C +P + CHC G+ +G
Sbjct: 323 CINAEPDQYRCTCPDGYSGRN--CEKAEHACTSNPCANGGSCHEVPSGFECHCPSGW-SG 379
Query: 226 PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHP 284
P +D++EC G C + V F C C + G C+ D +EC+ P
Sbjct: 380 P-TCALDIDECASNPCAA-GGTCVDQVDGFECICPEQWV----GATCQLDANECE--GKP 431
Query: 285 CGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCE 343
C SC N GGY C C GWK G C ++ ++C+ GG C++ GY C
Sbjct: 432 CLNAF--SCKNLIGGYYCDCIPGWK--GINCHINVNDCR--GQCQHGGTCKDLVNGYQCV 485
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
CP G+ C ER D+ + CH C E A G +C CP
Sbjct: 486 CPRGF----GGRHCELER-----DKCASSPCHSG--------GLC--EDLADGFHC-HCP 525
Query: 404 APDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGY----V 458
QG G P D+D C P C G RC N +G + C CPD +
Sbjct: 526 -----------QGFSG-PLCEVDVDLC--EPSPCRNGARCYNLEGDYYCACPDDFGGKNC 571
Query: 459 LAP----DGLSCVDADECALD----------PRICG-NGTCSNTRGG-YECQCSPGFTQG 502
P G +C D C D +CG +G C + GG + C C GFT
Sbjct: 572 SVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFT-- 629
Query: 503 PDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVC 561
++D+C C + +FRC CP G+ +G C + ++C+ +P
Sbjct: 630 GTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGW----EGELCDTNPNDCLPDPCHS 685
Query: 562 PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCD 621
C ++V + C C +G++ + E C D C +GG C ++ +F C
Sbjct: 686 RGRCYDLVNDFYCACDDGWKGKTC-HSREFQC-DAYTCS------NGGTCYDSGDTFRCA 737
Query: 622 CDAGFEPSEDGTDCIDRRTGTC 643
C G++ G+ C + +C
Sbjct: 738 CPPGWK----GSTCAVAKNSSC 755
Score = 118 bits (283), Expect = 1e-25
Identities = 81/255 (31%), Positives = 117/255 (45%), Gaps = 39/255 (15%)
Query: 386 ECCCSEGAAW-GRYCERC-PAPDSAEFMRI------CQGGMGRPNLTQDLDECRVRPDVC 437
EC CS G W GR+C+ C P P + C+ G +DL+ C
Sbjct: 261 ECRCSYG--WQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCT 318
Query: 438 VGGRCVNTD-GSFRCECPDGYVLAPDGLSCVDADE-CALDPRICGNG-TCSNTRGGYECQ 494
GG C+N + +RC CPDGY G +C A+ C +P C NG +C G+EC
Sbjct: 319 NGGTCINAEPDQYRCTCPDGY----SGRNCEKAEHACTSNP--CANGGSCHEVPSGFECH 372
Query: 495 CSPGFTQGPDQTC-VDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DID 552
C G++ GP TC +D+DECA + C + F C CP + G C+ D +
Sbjct: 373 CPSGWS-GP--TCALDIDECASNPCAAGGTCVDQVDGFECICPEQWV----GATCQLDAN 425
Query: 553 ECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCS-GGVC 611
EC +P + +C+N++G Y C C G++ N ++N+C Q C GG C
Sbjct: 426 ECEGKPCLNAFSCKNLIGGYYCDCIPGWK-------GINCHINVNDCRGQ---CQHGGTC 475
Query: 612 INTDGSFLCDCDAGF 626
+ + C C GF
Sbjct: 476 KDLVNGYQCVCPRGF 490
Score = 109 bits (261), Expect = 5e-23
Identities = 97/342 (28%), Positives = 144/342 (42%), Gaps = 49/342 (14%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
ID+C + Q C+ G TC D F+C C G+E + LC D + PC +C
Sbjct: 637 IDDC--LGQPCRNGGTCIDEVDAFRCFCPSGWEGE----LC-DTNPNDCLPDPCHSRGRC 689
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD-CRNTIGSYRCECKPGYTLR 185
+L F C C G++ C + D C +G C ++ ++RC C PG+ +
Sbjct: 690 YDLVNDFYCACDDGWKGKT----CHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGW--K 743
Query: 186 ENVCRDVDECS-RPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCV-DVNECREGGMVC 243
+ C S P P GTC ++ C C DG++ C + N+C + C
Sbjct: 744 GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEG---RTCTHNTNDCNP--LPC 798
Query: 244 RNGR-CRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYE 301
NG C + V FRCECAPG+ G +CR ++DEC P G +C + GY
Sbjct: 799 YNGGICVDGVNWFRCECAPGFA----GPDCRINIDECQSSPCAYG----ATCVDEINGYR 850
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER 361
CSC G G RC + + G C ++ G + W D + C+D R
Sbjct: 851 CSCPPG--RAGPRCQE--------VIGFGRSC--WSRGTPFPHGSSWVEDCNSCRCLDGR 898
Query: 362 KELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
++ C W C L +PE ++ R E+ P
Sbjct: 899 RD-CSKVW----CGWKPCLLAGQPEALSAQCPLGQRCLEKAP 935
Score = 54.0 bits (124), Expect = 2e-06
Identities = 31/95 (32%), Positives = 43/95 (45%), Gaps = 8/95 (8%)
Query: 760 PGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
P F C C G+ +G CA D+DECA P C + ++C+C + GA
Sbjct: 366 PSGFECHCPSGW--SGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWV----GAT 419
Query: 819 CR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
C+ D +ECE C N G Y C C G++
Sbjct: 420 CQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWK 454
Score = 48.4 bits (110), Expect = 1e-04
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 8/92 (8%)
Query: 760 PGRFRCVCGPGYRPAGEVCADVDE-CAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
P ++RC C GY +G C + C P CH ++C C +G+ G
Sbjct: 328 PDQYRCTCPDGY--SGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGW----SGPT 381
Query: 819 CR-DVDECERDTHTCQQICSNTEGSYECSCED 849
C D+DEC + C + +EC C +
Sbjct: 382 CALDIDECASNPCAAGGTCVDQVDGFECICPE 413
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 9/92 (9%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC- 819
FRC C PG++ G CA + P PC C + S+ C+CR G+E G C
Sbjct: 734 FRCACPPGWK--GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWE----GRTCT 787
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
+ ++C IC + + C C G+
Sbjct: 788 HNTNDCNPLPCYNGGICVDGVNWFRCECAPGF 819
Score = 46.4 bits (105), Expect = 4e-04
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 12/109 (11%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C + PG G F C+C G+ G C + +D+C +P C + ++ C C +G
Sbjct: 612 CVSQPG----GNFSCICDSGF--TGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSG 665
Query: 810 YELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
+E + N D C D + C + + C+C+DG+ +G C
Sbjct: 666 WEGELCDTNPND---CLPDPCHSRGRCYDLVNDFYCACDDGW--KGKTC 709
Score = 41.9 bits (94), Expect = 0.009
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 14/100 (14%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC 819
F C+C G+ G C + ++C P PC +C + + C C G+ G +C
Sbjct: 773 FSCICRDGWE--GRTCTHNTNDC--NPLPCYNGGICVDGVNWFRCECAPGFA----GPDC 824
Query: 820 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
R ++DEC+ C + Y CSC G + G C
Sbjct: 825 RINIDECQSSPCAYGATCVDEINGYRCSCPPG--RAGPRC 862
Score = 41.1 bits (92), Expect = 0.016
Identities = 40/134 (29%), Positives = 56/134 (41%), Gaps = 36/134 (26%)
Query: 749 DECAAIP----GLC---APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQ--LCHNT 798
D+CA+ P GLC A G F C C G+ +G +C DVD C P PC C+N
Sbjct: 500 DKCASSPCHSGGLCEDLADG-FHCHCPQGF--SGPLCEVDVDLC--EPSPCRNGARCYNL 554
Query: 799 DGSYDCLCRTGY-----ELDED---GANCRDVDECERDT------HTCQQIC-------S 837
+G Y C C + + + G CR +D C D +C S
Sbjct: 555 EGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVS 614
Query: 838 NTEGSYECSCEDGY 851
G++ C C+ G+
Sbjct: 615 QPGGNFSCICDSGF 628
Score = 35.9 bits (79), Expect = 0.61
Identities = 22/95 (23%), Positives = 39/95 (41%), Gaps = 9/95 (9%)
Query: 763 FRCVCGPGYRPAGEVCADVD-ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 821
F C C G++ G+ C + +C C+++ ++ C C G++ G+ C
Sbjct: 696 FYCACDDGWK--GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWK----GSTCAV 749
Query: 822 VDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKR 854
+ C C + S+ C C DG+E R
Sbjct: 750 AKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGR 784
Score = 35.1 bits (77), Expect = 1.1
Identities = 34/109 (31%), Positives = 41/109 (37%), Gaps = 20/109 (18%)
Query: 751 CAAIPGLCA-PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C + G C PG RC Y G C DEC P C + C C T
Sbjct: 249 CNLLHGGCTVPGECRC----SYGWQGRFC---DECVPYPGCVHGSCVEP---WQCNCETN 298
Query: 810 YELDEDGANC-RDVDECERDTHTCQQ--ICSNTE-GSYECSCEDGYEKR 854
+ G C +D++ C H C C N E Y C+C DGY R
Sbjct: 299 W----GGLLCDKDLNYCGSH-HPCTNGGTCINAEPDQYRCTCPDGYSGR 342
>AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein.
Length = 1238
Score = 188 bits (457), Expect = 1e-46
Identities = 176/632 (27%), Positives = 255/632 (40%), Gaps = 88/632 (13%)
Query: 23 CCCSVGHAW-GAPCEACPPRGSPAHTALCGEKPGEYINPVTNE-----TKPIDECDIMPQ 76
C CS G W G C+ C P H + C E P + N TN K ++ C
Sbjct: 262 CRCSYG--WQGRFCDECVPYPGCVHGS-CVE-PWQ-CNCETNWGGLLCDKDLNYCGSHHP 316
Query: 77 LCKPGTCHDT-PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC 135
GTC + P ++C C GY N C + P C C +P FEC
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRN----CEKAEHACTSNP-CANGGSCHEVPSGFEC 371
Query: 136 RCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDE 194
CP G+ S C D+DEC G C + + + C C P + D +E
Sbjct: 372 HCPSGW----SGPTCALDIDECASNPCAAGGTCVDQVDGFECIC-PEQWVGATCQLDANE 426
Query: 195 CSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGS 254
C +P +C+NL G Y C C G+K N ++VN+CR G G C++ V
Sbjct: 427 CEG-KPCLNAFSCKNLIGGYYCDCIPGWKG--INCHINVNDCR--GQCQHGGTCKDLVNG 481
Query: 255 FRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR 313
++C C G+ GR+C + D+C PC G C + G+ C C G+ G
Sbjct: 482 YQCVCPRGF----GGRHCELERDKCAS--SPCHSGG--LCEDLADGFHCHCPQGFS--GP 531
Query: 314 RC-VDRDECKELPYVCAGG-ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEA 371
C VD D C+ P C G C N G Y C CP + K +V +E C
Sbjct: 532 LCEVDVDLCEPSP--CRNGARCYNLEGDYYCACPDDFG-GKNCSV----PREPC----PG 580
Query: 372 GRCHRARPLQLARPECCCS-EGAAWGRYCE---RCPAPDSAEFMRICQGGMGRPNLTQDL 427
G C R + + G A C RC + F IC G +++
Sbjct: 581 GAC---RVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENI 637
Query: 428 DECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRIC-GNGTC 484
D+C +P C GG C++ +FRC CP G+ +G C + ++C DP C G C
Sbjct: 638 DDCLGQP--CRNGGTCIDEVDAFRCFCPSGW----EGELCDTNPNDCLPDP--CHSRGRC 689
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVD-ECAEGRASCTFRCHNTAGSFRCTCPYGYAVAA 543
+ + C C G+ +TC + +C S C+++ +FRC CP G+ +
Sbjct: 690 YDLVNDFYCACDDGWK---GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGST 746
Query: 544 DGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQE 603
V C+ P V C S+ C C +G+ + + N+C
Sbjct: 747 CAVAKNS--SCLPNPCVNGGTCVGSGASFSCICRDGW-------EGRTCTHNTNDCNPLP 797
Query: 604 DLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
+GG+C++ F C+C GF G DC
Sbjct: 798 -CYNGGICVDGVNWFRCECAPGFA----GPDC 824
Score = 176 bits (428), Expect = 3e-43
Identities = 185/625 (29%), Positives = 259/625 (41%), Gaps = 112/625 (17%)
Query: 20 KYLCCCSVGHAWGAPCE----ACPPR----GSPAHTALCGEK---PGEYINPVTNETKPI 68
+Y C C G++ G CE AC G H G + P + P I
Sbjct: 330 QYRCTCPDGYS-GRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTC--ALDI 386
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN 128
DEC P GTC D GF+C C + T L D +EC G+P C C N
Sbjct: 387 DECASNP-CAAGGTCVDQVDGFECICPEQWV-GATCQL--DANECE-GKP-CLNAFSCKN 440
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD-CRNTIGSYRCECKPGYTLREN 187
L G + C C PG++ ++ +V++C Q C HG C++ + Y+C C G+ R
Sbjct: 441 LIGGYYCDCIPGWK---GINCHINVNDCRGQ--CQHGGTCKDLVNGYQCVCPRGFGGRH- 494
Query: 188 VCR-DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG 246
C + D+C+ P G CE+L + CHC GF +GP + VDV+ C CRNG
Sbjct: 495 -CELERDKCASS-PCHSGGLCEDLADGFHCHCPQGF-SGPLCE-VDVDLCEPSP--CRNG 548
Query: 247 -RCRNTVGSFRCECAPGY--------TLTADGRNCRDVDECDELPHP----------CGR 287
RC N G + C C + G CR +D C P CG
Sbjct: 549 ARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGP 608
Query: 288 DGNPSCTNTNGG-YECSCGAGWKLVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCEC 344
G C + GG + C C +G+ G C + D+C P C GG C + + C C
Sbjct: 609 HGR--CVSQPGGNFSCICDSGF--TGTYCHENIDDCLGQP--CRNGGTCIDEVDAFRCFC 662
Query: 345 PAGWRFDKTAAVCVDERKELCYDEWEAGRCH-RARPLQLARP-ECCCSEGAAW-GRYCE- 400
P+GW + +C D C + CH R R L C C +G W G+ C
Sbjct: 663 PSGWEGE----LC-DTNPNDCLPD----PCHSRGRCYDLVNDFYCACDDG--WKGKTCHS 711
Query: 401 ---RCPAP---------DSAEFMRIC--QGGMGRPNLTQDLDECRVRPDVCV-GGRCVNT 445
+C A DS + R G G C P+ CV GG CV +
Sbjct: 712 REFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCL--PNPCVNGGTCVGS 769
Query: 446 DGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGP 503
SF C C DG+ +G +C + ++C +P C NG C + + C+C+PGF GP
Sbjct: 770 GASFSCICRDGW----EGRTCTHNTNDC--NPLPCYNGGICVDGVNWFRCECAPGFA-GP 822
Query: 504 DQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI----DECVQEPR 559
D +++DEC + C + +RC+CP G A G C+++ C
Sbjct: 823 DCR-INIDECQSSPCAYGATCVDEINGYRCSCPPGRA----GPRCQEVIGFGRSCWSRGT 877
Query: 560 VCPHACENVVGSYICKCPEGYRRTS 584
PH V C+C +G R S
Sbjct: 878 PFPHGSSWVEDCNSCRCLDGRRDCS 902
Score = 153 bits (371), Expect = 3e-36
Identities = 154/562 (27%), Positives = 226/562 (40%), Gaps = 101/562 (17%)
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDE----CE-DVDECGDQRICDHGD- 166
CS+G R +CV PG C ++ + C+ D++ CG C +G
Sbjct: 264 CSYGWQG-RFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGT 322
Query: 167 CRNTI-GSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG 225
C N YRC C GY+ R C + P G+C +P + CHC G+ +G
Sbjct: 323 CINAEPDQYRCTCPDGYSGRN--CEKAEHACTSNPCANGGSCHEVPSGFECHCPSGW-SG 379
Query: 226 PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHP 284
P +D++EC G C + V F C C + G C+ D +EC+ P
Sbjct: 380 P-TCALDIDECASNPCAA-GGTCVDQVDGFECICPEQWV----GATCQLDANECE--GKP 431
Query: 285 CGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCE 343
C SC N GGY C C GWK G C ++ ++C+ GG C++ GY C
Sbjct: 432 CLNAF--SCKNLIGGYYCDCIPGWK--GINCHINVNDCR--GQCQHGGTCKDLVNGYQCV 485
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
CP G+ C ER D+ + CH C E A G +C CP
Sbjct: 486 CPRGF----GGRHCELER-----DKCASSPCHSG--------GLC--EDLADGFHC-HCP 525
Query: 404 APDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGY----V 458
QG G P D+D C P C G RC N +G + C CPD +
Sbjct: 526 -----------QGFSG-PLCEVDVDLC--EPSPCRNGARCYNLEGDYYCACPDDFGGKNC 571
Query: 459 LAP----DGLSCVDADECALD----------PRICG-NGTCSNTRGG-YECQCSPGFTQG 502
P G +C D C D +CG +G C + GG + C C GFT
Sbjct: 572 SVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFT-- 629
Query: 503 PDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVC 561
++D+C C + +FRC CP G+ +G C + ++C+ +P
Sbjct: 630 GTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGW----EGELCDTNPNDCLPDPCHS 685
Query: 562 PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCD 621
C ++V + C C +G++ + E C D C +GG C ++ +F C
Sbjct: 686 RGRCYDLVNDFYCACDDGWKGKTC-HSREFQC-DAYTCS------NGGTCYDSGDTFRCA 737
Query: 622 CDAGFEPSEDGTDCIDRRTGTC 643
C G++ G+ C + +C
Sbjct: 738 CPPGWK----GSTCAVAKNSSC 755
Score = 118 bits (283), Expect = 1e-25
Identities = 81/255 (31%), Positives = 117/255 (45%), Gaps = 39/255 (15%)
Query: 386 ECCCSEGAAW-GRYCERC-PAPDSAEFMRI------CQGGMGRPNLTQDLDECRVRPDVC 437
EC CS G W GR+C+ C P P + C+ G +DL+ C
Sbjct: 261 ECRCSYG--WQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCT 318
Query: 438 VGGRCVNTD-GSFRCECPDGYVLAPDGLSCVDADE-CALDPRICGNG-TCSNTRGGYECQ 494
GG C+N + +RC CPDGY G +C A+ C +P C NG +C G+EC
Sbjct: 319 NGGTCINAEPDQYRCTCPDGY----SGRNCEKAEHACTSNP--CANGGSCHEVPSGFECH 372
Query: 495 CSPGFTQGPDQTC-VDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DID 552
C G++ GP TC +D+DECA + C + F C CP + G C+ D +
Sbjct: 373 CPSGWS-GP--TCALDIDECASNPCAAGGTCVDQVDGFECICPEQWV----GATCQLDAN 425
Query: 553 ECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCS-GGVC 611
EC +P + +C+N++G Y C C G++ N ++N+C Q C GG C
Sbjct: 426 ECEGKPCLNAFSCKNLIGGYYCDCIPGWK-------GINCHINVNDCRGQ---CQHGGTC 475
Query: 612 INTDGSFLCDCDAGF 626
+ + C C GF
Sbjct: 476 KDLVNGYQCVCPRGF 490
Score = 109 bits (261), Expect = 5e-23
Identities = 97/342 (28%), Positives = 144/342 (42%), Gaps = 49/342 (14%)
Query: 68 IDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
ID+C + Q C+ G TC D F+C C G+E + LC D + PC +C
Sbjct: 637 IDDC--LGQPCRNGGTCIDEVDAFRCFCPSGWEGE----LC-DTNPNDCLPDPCHSRGRC 689
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD-CRNTIGSYRCECKPGYTLR 185
+L F C C G++ C + D C +G C ++ ++RC C PG+ +
Sbjct: 690 YDLVNDFYCACDDGWKGKT----CHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGW--K 743
Query: 186 ENVCRDVDECS-RPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCV-DVNECREGGMVC 243
+ C S P P GTC ++ C C DG++ C + N+C + C
Sbjct: 744 GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEG---RTCTHNTNDCNP--LPC 798
Query: 244 RNGR-CRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYE 301
NG C + V FRCECAPG+ G +CR ++DEC P G +C + GY
Sbjct: 799 YNGGICVDGVNWFRCECAPGFA----GPDCRINIDECQSSPCAYG----ATCVDEINGYR 850
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDER 361
CSC G G RC + + G C ++ G + W D + C+D R
Sbjct: 851 CSCPPG--RAGPRCQE--------VIGFGRSC--WSRGTPFPHGSSWVEDCNSCRCLDGR 898
Query: 362 KELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCP 403
++ C W C L +PE ++ R E+ P
Sbjct: 899 RD-CSKVW----CGWKPCLLAGQPEALSAQCPLGQRCLEKAP 935
Score = 54.0 bits (124), Expect = 2e-06
Identities = 31/95 (32%), Positives = 43/95 (45%), Gaps = 8/95 (8%)
Query: 760 PGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
P F C C G+ +G CA D+DECA P C + ++C+C + GA
Sbjct: 366 PSGFECHCPSGW--SGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWV----GAT 419
Query: 819 CR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
C+ D +ECE C N G Y C C G++
Sbjct: 420 CQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWK 454
Score = 48.4 bits (110), Expect = 1e-04
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 8/92 (8%)
Query: 760 PGRFRCVCGPGYRPAGEVCADVDE-CAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
P ++RC C GY +G C + C P CH ++C C +G+ G
Sbjct: 328 PDQYRCTCPDGY--SGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGW----SGPT 381
Query: 819 CR-DVDECERDTHTCQQICSNTEGSYECSCED 849
C D+DEC + C + +EC C +
Sbjct: 382 CALDIDECASNPCAAGGTCVDQVDGFECICPE 413
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 9/92 (9%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC- 819
FRC C PG++ G CA + P PC C + S+ C+CR G+E G C
Sbjct: 734 FRCACPPGWK--GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWE----GRTCT 787
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
+ ++C IC + + C C G+
Sbjct: 788 HNTNDCNPLPCYNGGICVDGVNWFRCECAPGF 819
Score = 46.4 bits (105), Expect = 4e-04
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 12/109 (11%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C + PG G F C+C G+ G C + +D+C +P C + ++ C C +G
Sbjct: 612 CVSQPG----GNFSCICDSGF--TGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSG 665
Query: 810 YELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
+E + N D C D + C + + C+C+DG+ +G C
Sbjct: 666 WEGELCDTNPND---CLPDPCHSRGRCYDLVNDFYCACDDGW--KGKTC 709
Score = 41.9 bits (94), Expect = 0.009
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 14/100 (14%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC 819
F C+C G+ G C + ++C P PC +C + + C C G+ G +C
Sbjct: 773 FSCICRDGWE--GRTCTHNTNDC--NPLPCYNGGICVDGVNWFRCECAPGFA----GPDC 824
Query: 820 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
R ++DEC+ C + Y CSC G + G C
Sbjct: 825 RINIDECQSSPCAYGATCVDEINGYRCSCPPG--RAGPRC 862
Score = 41.1 bits (92), Expect = 0.016
Identities = 40/134 (29%), Positives = 56/134 (41%), Gaps = 36/134 (26%)
Query: 749 DECAAIP----GLC---APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQ--LCHNT 798
D+CA+ P GLC A G F C C G+ +G +C DVD C P PC C+N
Sbjct: 500 DKCASSPCHSGGLCEDLADG-FHCHCPQGF--SGPLCEVDVDLC--EPSPCRNGARCYNL 554
Query: 799 DGSYDCLCRTGY-----ELDED---GANCRDVDECERDT------HTCQQIC-------S 837
+G Y C C + + + G CR +D C D +C S
Sbjct: 555 EGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVS 614
Query: 838 NTEGSYECSCEDGY 851
G++ C C+ G+
Sbjct: 615 QPGGNFSCICDSGF 628
Score = 35.9 bits (79), Expect = 0.61
Identities = 22/95 (23%), Positives = 39/95 (41%), Gaps = 9/95 (9%)
Query: 763 FRCVCGPGYRPAGEVCADVD-ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 821
F C C G++ G+ C + +C C+++ ++ C C G++ G+ C
Sbjct: 696 FYCACDDGWK--GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWK----GSTCAV 749
Query: 822 VDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKR 854
+ C C + S+ C C DG+E R
Sbjct: 750 AKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGR 784
Score = 35.1 bits (77), Expect = 1.1
Identities = 34/109 (31%), Positives = 41/109 (37%), Gaps = 20/109 (18%)
Query: 751 CAAIPGLCA-PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C + G C PG RC Y G C DEC P C + C C T
Sbjct: 249 CNLLHGGCTVPGECRC----SYGWQGRFC---DECVPYPGCVHGSCVEP---WQCNCETN 298
Query: 810 YELDEDGANC-RDVDECERDTHTCQQ--ICSNTE-GSYECSCEDGYEKR 854
+ G C +D++ C H C C N E Y C+C DGY R
Sbjct: 299 W----GGLLCDKDLNYCGSH-HPCTNGGTCINAEPDQYRCTCPDGYSGR 342
>AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein
protein.
Length = 1640
Score = 182 bits (443), Expect = 5e-45
Identities = 216/835 (25%), Positives = 297/835 (35%), Gaps = 97/835 (11%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+DEC C+ C +TP + C C G+ S C ++ C+ G C+ CV
Sbjct: 237 VDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQH--HCV 293
Query: 128 NLP-GAFECRCPPGYRLTPSLDECEDVDECGDQR-ICDHGDCRNTIGSYRCECKPGYTLR 185
L C+C PG++L C C ++ C H C+ G RCEC GY L
Sbjct: 294 QLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHR-CQVVRGLARCECHVGYQLA 352
Query: 186 EN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVD-----VNECR 237
+ C DVDEC+ C +G C N G++ C C G++ G + C VN C
Sbjct: 353 ADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCE 411
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTN 297
C +G C +T C C GY L D R C DVD+C + PC + CTN
Sbjct: 412 ANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCAD--SPCCQQ---VCTNNP 465
Query: 298 GGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAA 355
GGYEC C AG++L G C D DEC C C N G + C C AG+R +
Sbjct: 466 GGYECGCYAGYRLSADGCGCEDVDECASSRGGCEH-HCTNLAGSFQCSCEAGYRLHEDRR 524
Query: 356 VCVDERKELCYDEWEAGRCH---RARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
C + + + E LQ P+ + +
Sbjct: 525 GCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKF 584
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCVGGRCV-NTDGSFRCECPDGYVLAPDGLSCVD--- 468
+C + + D+CR GG C+ DG C+CP+G+ +C
Sbjct: 585 VCLDDSFGHDCSLTCDDCRN------GGTCLLGLDG---CDCPEGWTGLICNETCPPDTF 635
Query: 469 ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS--CTFRCHN 526
C+ GTC + G C+C PG + C D C +G C +C N
Sbjct: 636 GKNCSFSCSCQNGGTCDSVTGA--CRCPPGVS---GTNCED--GCPKGYYGKHCRKKC-N 687
Query: 527 TAGSFRCTCPYGYAVAADGVHCRDID----------ECVQEPR-VCPH--ACENVVGSYI 573
A RC YG + G++ R C +E + V PH +C+ GS
Sbjct: 688 CANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGS-- 745
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGT 633
C C G+R + E C + G C + G C AGF+ + G
Sbjct: 746 CSCKAGFRGERCQAECELGYFGPG-CWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQ 804
Query: 634 DCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAW 693
+C GT C G +A C W
Sbjct: 805 EC---PVGT-----FGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCP---EGRW 853
Query: 694 GSEC-ELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECA 752
G C E+CPA AR D T L CA
Sbjct: 854 GLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRC-----SCA 908
Query: 753 AIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G C P C C PG+ G C + P C C+ + G C +G L
Sbjct: 909 N-DGHCHPATGHCSCAPGW--TGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCL 965
Query: 813 DEDG-ANCRDVDECERDTH--TCQQICSNTEG------SYECSCEDGYEKRGDAC 858
E G R +C + C+Q+C G S C+C G+ RG C
Sbjct: 966 CEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGW--RGTFC 1018
Score = 174 bits (424), Expect = 1e-42
Identities = 179/613 (29%), Positives = 241/613 (39%), Gaps = 91/613 (14%)
Query: 69 DECDIMPQLCKPGTCHD----TPTGFQ-CGCDHGYEHDNTSHLCRDVDECSWGRPPCRGM 123
DE + C G C P Q C C G++ + DVDEC C+
Sbjct: 194 DEEGCLSAECSAGLCFHGGRCVPGSAQPCHCPPGFQGPRCQY---DVDECRTHNGGCQH- 249
Query: 124 AQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG-DQRICDHGDCRNTIGSYRCECKPGY 182
+CVN PG++ C C PG+RL C ++ C C H + TI +RC+C+PG+
Sbjct: 250 -RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGF 308
Query: 183 TLRENVCRDVDECSRPRPVC-RNGT----CENLPGAYLCHCDDGFK-AGPNNDCVDVNEC 236
L+E D C R P RNG+ C+ + G C C G++ A C DV+EC
Sbjct: 309 QLQE----DGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDEC 364
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPC-GRDGNPS--C 293
G C +G C NT GSF+C C GY L ADGR C ++ E+ + C +G S C
Sbjct: 365 AAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEM--EIVNSCEANNGGCSHGC 421
Query: 294 TNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFD 351
++T+ G C+C G++L R C+D D+C + P C C N GGY C C AG+R
Sbjct: 422 SHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYAGYRLS 479
Query: 352 KTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAW---GRYCERCPAP--- 405
C D + C G C +C C G R C P
Sbjct: 480 ADGCGCED--VDECAS--SRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVD 535
Query: 406 --DSAEFMR----ICQGGMGRPNLTQDLD------ECRVRPDVCVGGRCVNTDGSFRCEC 453
F+R I P L QD D E +R + + + V D SF +C
Sbjct: 536 LDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDC 595
Query: 454 PDGYVLAPDGLSC---VDADEC--ALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCV 508
+G +C +D +C IC N TC G C S +C
Sbjct: 596 SLTCDDCRNGGTCLLGLDGCDCPEGWTGLIC-NETCPPDTFGKNCSFS--------CSCQ 646
Query: 509 DVDECAEGRASCTFRCHNTAGSFRCT--CPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
+ C +C RC C CP GY G HCR C R C
Sbjct: 647 NGGTCDSVTGAC--RCPPGVSGTNCEDGCPKGYY----GKHCRKKCNCANRGR-----CH 695
Query: 567 NVVGSYICKCPEGYRR----TSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDC 622
+ G+ +C P Y R T P C + +C + C DGS C C
Sbjct: 696 RLYGACLCD-PGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQS----CDKRDGS--CSC 748
Query: 623 DAGFEPSEDGTDC 635
AGF +C
Sbjct: 749 KAGFRGERCQAEC 761
Score = 169 bits (410), Expect = 5e-41
Identities = 146/460 (31%), Positives = 189/460 (41%), Gaps = 69/460 (15%)
Query: 194 ECSRPRPVC-RNGTCENLPG-AYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNT 251
ECS +C G C +PG A CHC GF+ GP DV+ECR C++ RC NT
Sbjct: 202 ECSAG--LCFHGGRC--VPGSAQPCHCPPGFQ-GPRCQ-YDVDECRTHNGGCQH-RCVNT 254
Query: 252 VGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDG-NPSCTN-TNGGYECSCGAGWK 309
GS+ CEC PG+ L D R C ++ C G G C T + C C G++
Sbjct: 255 PGSYLCECKPGFRLHTDSRTCLAINSC-----ALGNGGCQHHCVQLTITRHRCQCRPGFQ 309
Query: 310 LV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYD 367
L GR CV R C C C+ G CEC G++ C D D
Sbjct: 310 LQEDGRHCVRRSPCANRNGSCMH-RCQVVRGLARCECHVGYQLAADGKACED------VD 362
Query: 368 EWEAG--RCHRARPLQLARPECCCSEG---AAWGRYCERCPAPDSAEFMRICQGGMGRPN 422
E AG +C +C C G A GR C R E + C+ G
Sbjct: 363 ECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRI----EMEIVNSCEANNGG-- 416
Query: 423 LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNG 482
C G C +T C CP GY L D +C+D D+CA P C
Sbjct: 417 --------------CSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQ 459
Query: 483 TCSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAV 541
C+N GGYEC C G+ D C DVDECA R C C N AGSF+C+C GY +
Sbjct: 460 VCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRL 519
Query: 542 AADGVHCRDIDECVQE-----PRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDI 596
D C ++E + + P V P V+ + P+ ++ D E A
Sbjct: 520 HEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQD---ELPQLFQDDDVGADEEEA---- 572
Query: 597 NECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCI 636
E + L VC+ D SF DC + +G C+
Sbjct: 573 -ELRGEHTLTEKFVCL--DDSFGHDCSLTCDDCRNGGTCL 609
Score = 164 bits (399), Expect = 1e-39
Identities = 95/251 (37%), Positives = 113/251 (45%), Gaps = 8/251 (3%)
Query: 389 CSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGS 448
CS G + + RC P SA+ C G P D+DECR C RCVNT GS
Sbjct: 203 CSAGLCF--HGGRC-VPGSAQPCH-CPPGFQGPRCQYDVDECRTHNGGCQH-RCVNTPGS 257
Query: 449 FRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTC 507
+ CEC G+ L D +C+ + CAL C + T + CQC PGF D + C
Sbjct: 258 YLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC 317
Query: 508 VDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN 567
V CA SC RC G RC C GY +AADG C D+DEC C H C N
Sbjct: 318 VRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLN 377
Query: 568 VVGSYICKCPEGYR-RTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
GS+ C C GY Q E +N CE CS G C +T LC C G+
Sbjct: 378 TQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGY 436
Query: 627 EPSEDGTDCID 637
E D CID
Sbjct: 437 ELDTDQRTCID 447
Score = 158 bits (384), Expect = 7e-38
Identities = 183/655 (27%), Positives = 249/655 (38%), Gaps = 88/655 (13%)
Query: 49 LCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR 108
LC KPG ++ + I+ C + C+ T T +C C G++ C
Sbjct: 259 LCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCV 318
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GDQRICDHGDC 167
C+ C M +C + G C C GY+L CEDVDEC C HG C
Sbjct: 319 RRSPCANRNGSC--MHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG-C 375
Query: 168 RNTIGSYRCECKPGYTLREN--VC-----RDVDECSRPRPVCRNGTCENLPGAYLCHCDD 220
NT GS++C C GY L + C V+ C C +G C + LC C
Sbjct: 376 LNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPR 434
Query: 221 GFKAGPN-NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECD 279
G++ + C+DV++C + C C N G + C C GY L+ADG C DVDEC
Sbjct: 435 GYELDTDQRTCIDVDDCADS--PCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECA 492
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRC-------VDRDE----CKELPY 326
C CTN G ++CSC AG++L R C VD D + LP+
Sbjct: 493 SSRGGC----EHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPH 548
Query: 327 VCAGGE--CRNFNGGYV--CECPAGWRFDKTAA---VCVDERKELCYD-EWEAGRCHRAR 378
+ + + F V E A R + T VC+D+ +D C
Sbjct: 549 IAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDD--SFGHDCSLTCDDCRNGG 606
Query: 379 PLQLARPECCCSEGAAW-GRYC-ERCPAPD----SAEFMRICQGGMGRPNLTQDLDECRV 432
L C C EG W G C E CP PD + F CQ G ++T CR
Sbjct: 607 TCLLGLDGCDCPEG--WTGLICNETCP-PDTFGKNCSFSCSCQNGGTCDSVT---GACRC 660
Query: 433 RPDVCVGGRCVNTDGSFRCECPDGYV--LAPDGLSCVDADECALDPRICGNGTCSNTRGG 490
P V G C DG CP GY +C + C R+ G C G
Sbjct: 661 PPGVS-GTNC--EDG-----CPKGYYGKHCRKKCNCANRGRC---HRLYGACLCDPGLYG 709
Query: 491 YECQCS-PGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR 549
C + P + GP C + +C + T C GS C+C G+ C
Sbjct: 710 RFCHLTCPPWAFGPG--CSEECQCVQPH---TQSCDKRDGS--CSCKAGFRGERCQAECE 762
Query: 550 --DIDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDL 605
+ CP AC++V G +CP G++ Q+ +N C
Sbjct: 763 LGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVN-CSSSCS- 820
Query: 606 CSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTG-----TCYRSLVSGRCEPE 655
C G C G C C G + DC + R G C + RC+PE
Sbjct: 821 CGGAPCHGVTGQ--CRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPE 873
Score = 91.1 bits (216), Expect = 2e-17
Identities = 168/684 (24%), Positives = 229/684 (33%), Gaps = 110/684 (16%)
Query: 25 CSVGHAWGAPCEA-CPPRGSPAH--TALCGEKPG---EYINPVTNETKPIDECDIMPQLC 78
C VG +G C + C G+P H T C PG E E + C + C
Sbjct: 806 CPVG-TFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPAC 864
Query: 79 KPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVN----LPGAFE 134
+ D TG C C G+ C+DV W P C+ C N P
Sbjct: 865 QHAARCDPETG-ACLCLPGF----VGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGH 919
Query: 135 CRCPPGYRLTPSLDECED---VDECGDQRICD--HGDCRNTIGSYRCECKPGYT--LREN 187
C C PG+ C+ +C C HG C G C C+ GY E
Sbjct: 920 CSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISG--LCLCEAGYVGPRCEQ 977
Query: 188 VCRDVDECSRPRPVCR---NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCR 244
C +C+ C+++ GA C C G++ C G+ CR
Sbjct: 978 QCPQGHFGPGCEQLCQCQHGAACDHVSGA--CTCPAGWR---GTFCEHACPAGFFGLDCR 1032
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGR---NCRDVDECDELPHPCGRD----GNPSCTNTN 297
+ C T G+ C+ G L GR C + H C + SC +
Sbjct: 1033 SA-CNCTAGA-ACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVH 1090
Query: 298 GGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVC 357
G +C C GW +G C+ + P G CR + C C G D + C
Sbjct: 1091 G--QCHCAPGW--MGPSCL-----QACPAGLYGDNCR-----HSCLCQNGGTCDPVSGHC 1136
Query: 358 VDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCE----RCPAPDSAEFMRI 413
C + W C + + R C S G G C+ RC P +
Sbjct: 1137 A------CPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDK- 1189
Query: 414 CQGGMGRPNLTQDLDE-CRVRPDVCVGGRCVNTDGSFRCECPDGYV------LAPDGL-- 464
CQ P L E C R C + G+ C CP G+ P G
Sbjct: 1190 CQS----PCLRGWFGEACAQRCSCPPAAACHHVTGA--CRCPPGFTGSGCEQACPPGSFG 1243
Query: 465 -SCVDADECALDPRIC--GNGTCSNTRG--GYECQ--CSPG-FTQGPDQT--CVDVDECA 514
C +C + C GTCS G G CQ C PG + G +Q C++ C
Sbjct: 1244 EDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCD 1303
Query: 515 EGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYIC 574
+C TCP G G +C + C Q AC+ V G+ C
Sbjct: 1304 AATGACRCPTGFLGTDCNLTCPQG----RFGPNCTHVCGCGQGA-----ACDPVTGT--C 1352
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTD 634
CP G + + CE +GG+C ++GS C C G+
Sbjct: 1353 LCPPGRAGVRCERGCPQNRFGVG-CEHTCSCRNGGLCHASNGS--CSCGLGWTGRHCELA 1409
Query: 635 CIDRRTG-TCYRSLV---SGRCEP 654
C R G C+ + CEP
Sbjct: 1410 CPPGRYGAACHLECSCHNNSTCEP 1433
Score = 90.2 bits (214), Expect = 3e-17
Identities = 163/634 (25%), Positives = 214/634 (33%), Gaps = 111/634 (17%)
Query: 78 CKPGT--CHDTP--TGFQC--GCDHGYEHDNTSHLCRDVDECSWGRPPC---RGMAQC-V 127
C P T C P TGF C CD G+ + SH C CS G C G+ C
Sbjct: 913 CHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCN----CSAGHGSCDAISGLCLCEA 968
Query: 128 NLPGA-FECRCPPGYRLTPSLDECEDVDECGDQRICDH--GDCRNTIG--SYRCE--CKP 180
G E +CP G+ P CE + +C CDH G C G CE C
Sbjct: 969 GYVGPRCEQQCPQGH-FGPG---CEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHACPA 1024
Query: 181 GYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGG 240
G+ + CR C+ C+ + G+ C C G + GP C + G
Sbjct: 1025 GFFGLD--CRSACNCTA------GAACDAVNGS--CLCPAG-RRGPR--CAETCPAHTYG 1071
Query: 241 ------MVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCT 294
C NG + V +C CAPG+ + + C D H C +C
Sbjct: 1072 HNCSQACACFNGASCDPVHG-QCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCD 1130
Query: 295 NTNGGYECSCGAGWKLVG--RRCVDRDE---CKELPYVCAGGECRNFNGGYVCECPAGWR 349
+G C+C GW + + C+ RD C+ GG C G C CPAGW
Sbjct: 1131 PVSG--HCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGR--CLCPAGWT 1186
Query: 350 FDKTAAVCV-DERKELCYDEWE---AGRCHRARPLQLARPECC---CSEGAAWGRYCERC 402
DK + C+ E C A CH P C + G + E C
Sbjct: 1187 GDKCQSPCLRGWFGEACAQRCSCPPAAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDC 1246
Query: 403 ----------PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDV-----CV-GGRCVNTD 446
PA A C G P+ Q R P C+ GG C
Sbjct: 1247 AQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAAT 1306
Query: 447 GSFRCECPDGY------VLAPDGL---SCVDADEC----ALDPRICGNGTCSNTRGGYEC 493
G+ C CP G+ + P G +C C A DP + G C R G C
Sbjct: 1307 GA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDP-VTGTCLCPPGRAGVRC 1363
Query: 494 Q--CSPG-FTQGPDQTCV--DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC 548
+ C F G + TC + C SC+ T CP G AA + C
Sbjct: 1364 ERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLEC 1423
Query: 549 RDIDECVQEPRVCPHACENVVGSYICK--CPEGYRRTSAPQDSENACEDINECEEQEDLC 606
+ EP C C+ CP G+ C+ + C+ C
Sbjct: 1424 SCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGA--------GCQGLCWCQHGAP-C 1474
Query: 607 S--GGVCINTDGSFLCDCDAGFEPSEDGTDCIDR 638
G C+ G C+ G EP G C R
Sbjct: 1475 DPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQR 1508
Score = 76.2 bits (179), Expect = 5e-13
Identities = 58/171 (33%), Positives = 74/171 (43%), Gaps = 21/171 (12%)
Query: 494 QCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR-CTCPYGYAVAADGVHCR-DI 551
+C G+ Q PD+ EC+ G RC GS + C CP G+ G C+ D+
Sbjct: 184 RCCRGWMQQPDEEGCLSAECSAGLCFHGGRC--VPGSAQPCHCPPGF----QGPRCQYDV 237
Query: 552 DECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVC 611
DEC C H C N GSY+C+C G+R + DS C IN C C
Sbjct: 238 DECRTHNGGCQHRCVNTPGSYLCECKPGFRLHT---DSRT-CLAINSCALGNGGCQHHCV 293
Query: 612 INTDGSFLCDCDAGFEPSEDGTDCIDR-----RTGTCYR--SLVSG--RCE 653
T C C GF+ EDG C+ R R G+C +V G RCE
Sbjct: 294 QLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCE 344
Score = 72.1 bits (169), Expect = 8e-12
Identities = 37/104 (35%), Positives = 48/104 (46%), Gaps = 5/104 (4%)
Query: 756 GLCAPGRFR-CVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 813
G C PG + C C PG++ G C DVDEC C C NT GSY C C+ G+ L
Sbjct: 212 GRCVPGSAQPCHCPPGFQ--GPRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLH 269
Query: 814 EDGANCRDVDECERDTHTCQQICSN-TEGSYECSCEDGYEKRGD 856
D C ++ C CQ C T + C C G++ + D
Sbjct: 270 TDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQED 313
Score = 65.7 bits (153), Expect = 7e-10
Identities = 157/634 (24%), Positives = 213/634 (33%), Gaps = 99/634 (15%)
Query: 70 ECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCR-DV--DECSWGRPPCRGMAQ 125
+C + C+ G TC G C C G+ + C D CS+ C+
Sbjct: 594 DCSLTCDDCRNGGTCLLGLDG--CDCPEGWTGLICNETCPPDTFGKNCSFSCS-CQNGGT 650
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECED---VDECGDQRIC-DHGDCRNTIGSYRCECKPG 181
C ++ GA CRCPPG T D C C + C + G C G+ C C PG
Sbjct: 651 CDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGA--CLCDPG 706
Query: 182 YTLR-----------ENVCRDVDECSRPR-PVC--RNGTCENLPG--AYLC--HCDDGFK 223
R C + +C +P C R+G+C G C C+ G+
Sbjct: 707 LYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGY- 765
Query: 224 AGPNNDCVDVNECREGGMVCR--NGRC-RNTVGSFRCE-CAPGYTLTADGRNCRDVDECD 279
GP C C G+ C +G C + F+ E C + G NC C
Sbjct: 766 FGPG--CWQACTC-PVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCG 822
Query: 280 ELPHPC-GRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVC--AGGECRNF 336
PC G G C G +C G C + + C G C
Sbjct: 823 GA--PCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCL 880
Query: 337 NG--GYVCE--CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEG 392
G G C+ CPAGW C C+ G C A + C G
Sbjct: 881 PGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHP--ATGHCSCAPGWTGFSCQRACDTG 938
Query: 393 AAWGRYCE---RCPAP----DSAEFMRICQGGMGRPNLTQDLDECRVRP---DVCV---G 439
WG C C A D+ + +C+ G P Q + P +C G
Sbjct: 939 -HWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHG 997
Query: 440 GRCVNTDGSFRCECPDGY------VLAPD---GLSCVDADEC---ALDPRICGNGTCSNT 487
C + G+ C CP G+ P GL C A C A + G+ C
Sbjct: 998 AACDHVSGA--CTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAG 1055
Query: 488 RGGYEC-QCSPGFTQGPDQTCVDVDECAEGRASCT---FRCHNTAGSFRCTCPYGYAVAA 543
R G C + P T G C C G ASC +CH G +C
Sbjct: 1056 RRGPRCAETCPAHTYG--HNCSQACACFNG-ASCDPVHGQCHCAPGWMGPSCLQACPAGL 1112
Query: 544 DGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINE-CEEQ 602
G +CR C C+ V G C CPEG+ + + E D+ C
Sbjct: 1113 YGDNCRHSCLCQN-----GGTCDPVSGH--CACPEGWAGLAC--EKECLPRDVRAGCRHS 1163
Query: 603 EDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCI 636
+GG+C G C C AG+ + + C+
Sbjct: 1164 GGCLNGGLCDPHTGR--CLCPAGWTGDKCQSPCL 1195
Score = 48.8 bits (111), Expect = 8e-05
Identities = 101/378 (26%), Positives = 126/378 (33%), Gaps = 50/378 (13%)
Query: 9 SCAGAVGVPQTKYLCCCSVGHAWGAPCE-ACPPRGSPAHTALCGEKPGEYINPVTNETKP 67
SC A C C G G+ CE ACPP A + PGE NP +
Sbjct: 1208 SCPPAAACHHVTGACRCPPGFT-GSGCEQACPPGSFGEDCAQMCQCPGE--NPACHPATG 1264
Query: 68 IDEC------DIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR--------DVD-E 112
C Q C PG + CGC +G D + CR D +
Sbjct: 1265 TCSCAAGYHGPSCQQRCPPGR-YGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLT 1323
Query: 113 CSWGR--PPCRGMAQC----VNLPGAFECRCPPGYRLTPSLDEC-EDVDECGDQRIC--- 162
C GR P C + C P C CPPG C ++ G + C
Sbjct: 1324 CPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCR 1383
Query: 163 DHGDCRNTIGSYRCECKPGYTLR--ENVC---RDVDECSRPRPVCRNGTCENLPGAYLCH 217
+ G C + GS C C G+T R E C R C N TCE P C
Sbjct: 1384 NGGLCHASNGS--CSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCE--PATGTCR 1439
Query: 218 CDDGFKA-GPNNDCVD--VNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRD 274
C GF + C +G C++G + + S RC C G+ R C
Sbjct: 1440 CGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPI-SGRCLCPAGFHGHFCERGCEP 1498
Query: 275 VDECDELPHPCGRDGNPSCTNTNGGYEC---SCGAGWKLVGRRCVDRDECKELPYVCAGG 331
+ C DG C G C GA L RR C L C GG
Sbjct: 1499 GSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSC-TLHCDCGGG 1557
Query: 332 -ECRNFNGGYVCECPAGW 348
+C +G C C G+
Sbjct: 1558 ADCDPVSG--QCHCVDGY 1573
Score = 46.8 bits (106), Expect = 3e-04
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 5/55 (9%)
Query: 804 CLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA 857
C C G++ G C+ DVDEC CQ C NT GSY C C+ G+ D+
Sbjct: 222 CHCPPGFQ----GPRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDS 272
>AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein.
Length = 1246
Score = 182 bits (443), Expect = 5e-45
Identities = 213/832 (25%), Positives = 291/832 (34%), Gaps = 91/832 (10%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+DEC C+ C +TP + C C G+ S C ++ C+ G C+ CV
Sbjct: 74 VDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQ--HHCV 130
Query: 128 NLP-GAFECRCPPGYRLTPSLDECEDVDECGDQR-ICDHGDCRNTIGSYRCECKPGYTLR 185
L C+C PG++L C C ++ C H C+ G RCEC GY L
Sbjct: 131 QLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH-RCQVVRGLARCECHVGYQLA 189
Query: 186 EN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVD-----VNECR 237
+ C DVDEC+ C +G C N G++ C C G++ G + C VN C
Sbjct: 190 ADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCE 248
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTN 297
C +G C +T C C GY L D R C DVD+C + PC + CTN
Sbjct: 249 ANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCAD--SPCCQQ---VCTNNP 302
Query: 298 GGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAA 355
GGYEC C AG++L G C D DEC C C N G + C C AG+R +
Sbjct: 303 GGYECGCYAGYRLSADGCGCEDVDECASSRGGCE-HHCTNLAGSFQCSCEAGYRLHEDRR 361
Query: 356 VCVDERKELCYDEWE---AGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
C + + + E LQ P+ + +
Sbjct: 362 GCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKF 421
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCVGGRC-VNTDGSFRCECPDGYVLAPDGLSC---VD 468
+C + + D+CR GG C + DG C+CP+G+ +C
Sbjct: 422 VCLDDSFGHDCSLTCDDCR------NGGTCLLGLDG---CDCPEGWTGLICNETCPPDTF 472
Query: 469 ADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTF----R 523
C+ GTC + G C+C PG + + C R C R
Sbjct: 473 GKNCSFSCSCQNGGTCDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGR 530
Query: 524 CHNTAGSFRCT-------CPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKC 576
CH G+ C C A G C + +CVQ P +C+ GS C C
Sbjct: 531 CHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQ-PHT--QSCDKRDGS--CSC 585
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCI 636
G+R + E C + G C + G C AGF+ + G +C
Sbjct: 586 KAGFRGERCQAECELGYFGPG-CWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQEC- 643
Query: 637 DRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSE 696
GT C G +A C WG
Sbjct: 644 --PVGT-----FGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADC---PEGRWGLG 693
Query: 697 C-ELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP 755
C E+CPA AR D T L CA
Sbjct: 694 CQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRC-----SCAN-D 747
Query: 756 GLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 815
G C P C C PG+ G C + P C C+ + G C +G L E
Sbjct: 748 GHCHPATGHCSCAPGW--TGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEA 805
Query: 816 G-ANCRDVDECERDTH--TCQQICSNTEG------SYECSCEDGYEKRGDAC 858
G R +C + C+Q+C G S C+C G+ RG C
Sbjct: 806 GYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGW--RGTFC 855
Score = 171 bits (415), Expect = 1e-41
Identities = 169/568 (29%), Positives = 227/568 (39%), Gaps = 83/568 (14%)
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG-DQRICDHGDC 167
DVDEC C+ +CVN PG++ C C PG+RL C ++ C C H
Sbjct: 73 DVDECRTHNGGCQH--RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCV 130
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVC-RNGT----CENLPGAYLCHCDDGF 222
+ TI +RC+C+PG+ L+E D C R P RNG+ C+ + G C C G+
Sbjct: 131 QLTITRHRCQCRPGFQLQE----DGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGY 186
Query: 223 K-AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDEL 281
+ A C DV+EC G C +G C NT GSF+C C GY L ADGR C ++ E+
Sbjct: 187 QLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEM--EI 243
Query: 282 PHPC-GRDGNPS--CTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGECRNF 336
+ C +G S C++T+ G C+C G++L R C+D D+C + P C C N
Sbjct: 244 VNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVCTNN 301
Query: 337 NGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAW- 395
GGY C C AG+R C D + C G C +C C G
Sbjct: 302 PGGYECGCYAGYRLSADGCGCED--VDECAS--SRGGCEHHCTNLAGSFQCSCEAGYRLH 357
Query: 396 --GRYCERCPAP-----DSAEFMR----ICQGGMGRPNLTQDLD------ECRVRPDVCV 438
R C P F+R I P L QD D E +R + +
Sbjct: 358 EDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTL 417
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSC---VDADEC--ALDPRICGNGTCSNTRGGYEC 493
+ V D SF +C +G +C +D +C IC N TC G C
Sbjct: 418 TEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLIC-NETCPPDTFGKNC 476
Query: 494 QCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCT--CPYGYAVAADGVHCRDI 551
S +C + C +C RC C CP GY G HCR
Sbjct: 477 SFS--------CSCQNGGTCDSVTGAC--RCPPGVSGTNCEDGCPKGYY----GKHCRKK 522
Query: 552 DECVQEPRVCPHACENVVGSYICKCPEGYRR----TSAPQDSENACEDINECEEQEDLCS 607
C R C + G+ +C P Y R T P C + +C +
Sbjct: 523 CNCANRGR-----CHRLYGACLCD-PGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQS- 575
Query: 608 GGVCINTDGSFLCDCDAGFEPSEDGTDC 635
C DGS C C AGF +C
Sbjct: 576 ---CDKRDGS--CSCKAGFRGERCQAEC 598
Score = 164 bits (398), Expect = 1e-39
Identities = 135/441 (30%), Positives = 177/441 (40%), Gaps = 62/441 (14%)
Query: 212 GAYLCHCDD-GFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G Y CH G+ + DV+ECR C++ RC NT GS+ CEC PG+ L D R
Sbjct: 52 GCYPCHLGQAGYPVSAGDQRPDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSR 110
Query: 271 NCRDVDECDELPHPCGRDG-NPSCTN-TNGGYECSCGAGWKLV--GRRCVDRDECKELPY 326
C ++ C G G C T + C C G++L GR CV R C
Sbjct: 111 TCLAINSC-----ALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNG 165
Query: 327 VCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAG--RCHRARPLQLAR 384
C C+ G CEC G++ C D DE AG +C
Sbjct: 166 SCMH-RCQVVRGLARCECHVGYQLAADGKACED------VDECAAGLAQCAHGCLNTQGS 218
Query: 385 PECCCSEG---AAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
+C C G A GR C R E + C+ G C G
Sbjct: 219 FKCVCHAGYELGADGRQCYRI----EMEIVNSCEANNGG----------------CSHG- 257
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
C +T C CP GY L D +C+D D+CA P C C+N GGYEC C G+
Sbjct: 258 CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYAGYRL 315
Query: 502 GPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQE--- 557
D C DVDECA R C C N AGSF+C+C GY + D C ++E + +
Sbjct: 316 SADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDG 375
Query: 558 --PRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTD 615
P V P V+ + P+ ++ D E A E + L VC+ D
Sbjct: 376 ELPFVRPLPHIAVLQD---ELPQLFQDDDVGADEEEA-----ELRGEHTLTEKFVCL--D 425
Query: 616 GSFLCDCDAGFEPSEDGTDCI 636
SF DC + +G C+
Sbjct: 426 DSFGHDCSLTCDDCRNGGTCL 446
Score = 158 bits (384), Expect = 7e-38
Identities = 183/655 (27%), Positives = 249/655 (38%), Gaps = 88/655 (13%)
Query: 49 LCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR 108
LC KPG ++ + I+ C + C+ T T +C C G++ C
Sbjct: 96 LCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCV 155
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRI-CDHGDC 167
C+ C M +C + G C C GY+L CEDVDEC C HG C
Sbjct: 156 RRSPCANRNGSC--MHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG-C 212
Query: 168 RNTIGSYRCECKPGYTLREN--VC-----RDVDECSRPRPVCRNGTCENLPGAYLCHCDD 220
NT GS++C C GY L + C V+ C C +G C + LC C
Sbjct: 213 LNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPR 271
Query: 221 GFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECD 279
G++ + C+DV++C + C C N G + C C GY L+ADG C DVDEC
Sbjct: 272 GYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECA 329
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRC-------VDRDE----CKELPY 326
C CTN G ++CSC AG++L R C VD D + LP+
Sbjct: 330 SSRGGC----EHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPH 385
Query: 327 VCAGGE--CRNFNGGYV--CECPAGWRFDKTAA---VCVDERKELCYD-EWEAGRCHRAR 378
+ + + F V E A R + T VC+D+ +D C
Sbjct: 386 IAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDD--SFGHDCSLTCDDCRNGG 443
Query: 379 PLQLARPECCCSEGAAW-GRYC-ERCPAPD----SAEFMRICQGGMGRPNLTQDLDECRV 432
L C C EG W G C E CP PD + F CQ G ++T CR
Sbjct: 444 TCLLGLDGCDCPEG--WTGLICNETCP-PDTFGKNCSFSCSCQNGGTCDSVT---GACRC 497
Query: 433 RPDVCVGGRCVNTDGSFRCECPDGYV--LAPDGLSCVDADECALDPRICGNGTCSNTRGG 490
P V G C DG CP GY +C + C R+ G C G
Sbjct: 498 PPGVS-GTNC--EDG-----CPKGYYGKHCRKKCNCANRGRC---HRLYGACLCDPGLYG 546
Query: 491 YECQCS-PGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR 549
C + P + GP C + +C + T C GS C+C G+ C
Sbjct: 547 RFCHLTCPPWAFGPG--CSEECQCVQPH---TQSCDKRDGS--CSCKAGFRGERCQAECE 599
Query: 550 --DIDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDL 605
+ CP AC++V G +CP G++ Q+ +N C
Sbjct: 600 LGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVN-CSSSCS- 657
Query: 606 CSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTG-----TCYRSLVSGRCEPE 655
C G C G C C G + DC + R G C + RC+PE
Sbjct: 658 CGGAPCHGVTGQ--CRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPE 710
Score = 157 bits (382), Expect = 1e-37
Identities = 84/214 (39%), Positives = 99/214 (46%), Gaps = 4/214 (1%)
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
D+DECR C RCVNT GS+ CEC G+ L D +C+ + CAL C +
Sbjct: 73 DVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 131
Query: 486 NTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
T + CQC PGF D + CV CA SC RC G RC C GY +AAD
Sbjct: 132 LTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAAD 191
Query: 545 GVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR-RTSAPQDSENACEDINECEEQE 603
G C D+DEC C H C N GS+ C C GY Q E +N CE
Sbjct: 192 GKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANN 251
Query: 604 DLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
CS G C +T LC C G+E D CID
Sbjct: 252 GGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCID 284
Score = 140 bits (339), Expect = 2e-32
Identities = 109/357 (30%), Positives = 152/357 (42%), Gaps = 48/357 (13%)
Query: 131 GAFECRC-PPGYRLTPSLDECEDVDECGDQRI-CDHGDCRNTIGSYRCECKPGYTLREN- 187
G + C GY ++ D+ DVDEC C H C NT GSY CECKPG+ L +
Sbjct: 52 GCYPCHLGQAGYPVSAG-DQRPDVDECRTHNGGCQHR-CVNTPGSYLCECKPGFRLHTDS 109
Query: 188 -VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRN 245
C ++ C+ C++ + + C C GF+ + CV + C C +
Sbjct: 110 RTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH 169
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
RC+ G RCEC GY L ADG+ C DVDEC C C NT G ++C C
Sbjct: 170 -RCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAH----GCLNTQGSFKCVCH 224
Query: 306 AGWKL--VGRRC--VDRD---ECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV 358
AG++L GR+C ++ + C+ C+ G C + + G +C CP G+ D C+
Sbjct: 225 AGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCI 283
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
D + C D + C + EC C G R+ G
Sbjct: 284 D--VDDCAD---SPCCQQVCTNNPGGYECGCYAG------------------YRLSADGC 320
Query: 419 GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
G +D+DEC C C N GSF+C C GY L D C +E +D
Sbjct: 321 G----CEDVDECASSRGGC-EHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVD 372
Score = 102 bits (244), Expect = 6e-21
Identities = 211/845 (24%), Positives = 280/845 (33%), Gaps = 128/845 (15%)
Query: 64 ETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGM 123
E + ++ C+ C G C T G C C GYE D C DVD+C+ P C+ +
Sbjct: 240 EMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCA-DSPCCQQV 297
Query: 124 AQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRI-CDHGDCRNTIGSYR--CEC-- 178
C N PG +EC C GYRL+ CEDVDEC R C+H C N GS++ CE
Sbjct: 298 --CTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEH-HCTNLAGSFQCSCEAGY 354
Query: 179 -----KPGYTLRENVCRDVD-ECSRPRPVCRNGTCEN-LPGAYLCHCDDGFKAGPNND-- 229
+ G + E D+D E RP+ ++ LP + DD A
Sbjct: 355 RLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQ---DDDVGADEEEAEL 411
Query: 230 -----------CVDVNECREGGMVCRNGRCRNT--VGSFRCECAPGYTLTADGRNCRDVD 276
C+D + + + C + R T +G C+C G+T C
Sbjct: 412 RGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDT 471
Query: 277 ECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNF 336
C +C + G C C G + G C D C + Y G CR
Sbjct: 472 FGKNCSFSCSCQNGGTCDSVTGA--CRCPPG--VSGTNC--EDGCPKGYY---GKHCRK- 521
Query: 337 NGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGR-CHRARPLQLARPECCCSEGAAW 395
C C R + C LC D GR CH P P C E
Sbjct: 522 ----KCNCANRGRCHRLYGAC------LC-DPGLYGRFCHLTCPPWAFGPGCS-EECQCV 569
Query: 396 GRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP---DVC---VGGRCVNTDGSF 449
+ + C D + C+ G + + P C VG C + G
Sbjct: 570 QPHTQSCDKRDGS---CSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGEC 626
Query: 450 RCECPDGYVLAPDGLSCVDAD---ECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT 506
CP G+ G C C+ CG C G +C+C PG T G D
Sbjct: 627 GKRCPAGFQGEDCGQECPVGTFGVNCSSSCS-CGGAPCHGVTG--QCRCPPGRT-GED-- 680
Query: 507 CVDVDECAEGR--ASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA 564
C + D C EGR C C + RC G + G + Q+ VCP
Sbjct: 681 C-EAD-CPEGRWGLGCQEICPACQHAARCDPETGACLCLPGF----VGSRCQD--VCPAG 732
Query: 565 CENVVGSYICKCP-EGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCD 623
C C +G+ P +C + C G D S C+C
Sbjct: 733 WYGPSCQTRCSCANDGHCH---PATGHCSCAPGWTGFSCQRACDTGHW-GPDCSHPCNCS 788
Query: 624 AGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKA 683
AG D I C V RCE + HV+ A
Sbjct: 789 AG----HGSCDAISGLC-LCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGA 843
Query: 684 QCCCTLGAAW-GSECE-LCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXX 741
CT A W G+ CE CPA LD +A N T
Sbjct: 844 ---CTCPAGWRGTFCEHACPA--GFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRC 898
Query: 742 LDVFADVDECAAIP--------GLCAPGRFRCVCGPGYRPAGEVCADV-------DECAV 786
+ D A GLC P RC+C G+ G+ C + CA
Sbjct: 899 AEKCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGW--TGDKCQSPCLRGWFGEACAQ 956
Query: 787 R-PPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC 845
R P CH+ G+ C C G+ G+ C R C+Q+C G C
Sbjct: 957 RCSCPPAAACHHVTGA--CRCPPGF----TGSGCEQGCPPGRYGPGCEQLCGCLNGG-SC 1009
Query: 846 SCEDG 850
G
Sbjct: 1010 DAATG 1014
Score = 81.0 bits (191), Expect = 2e-14
Identities = 168/686 (24%), Positives = 233/686 (33%), Gaps = 100/686 (14%)
Query: 4 NEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPC-EACP-PRGSPAHTAL--CGEK-PGEYI 58
++ D SC+ G + C +G+ +G C +AC P G + CG++ P +
Sbjct: 577 DKRDGSCSCKAGFRGERCQAECELGY-FGPGCWQACTCPVGVACDSVSGECGKRCPAGFQ 635
Query: 59 NPVTNETKPIDECDI-MPQLCKPG--TCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECS 114
+ P+ + C G CH TG QC C G T C D E
Sbjct: 636 GEDCGQECPVGTFGVNCSSSCSCGGAPCHGV-TG-QCRCPPG----RTGEDCEADCPEGR 689
Query: 115 WGR------PPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV---DECGDQRIC-DH 164
WG P C+ A+C GA C C PG+ + D C C + C +
Sbjct: 690 WGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCAND 747
Query: 165 GDCRNTIGSYRCECKPGYT--LRENVCRDVD---ECSRP-RPVCRNGTCENLPGAYLCHC 218
G C G C C PG+T + C +CS P +G+C+ + G LC C
Sbjct: 748 GHCHPATG--HCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISG--LCLC 803
Query: 219 DDGFKAGPNNDCVDVNECREGGM--------VCRNGRCRNTVGSFRCECAPGYTLTADGR 270
+ G+ GP + +C +G C++G + V S C C G+ T
Sbjct: 804 EAGY-VGPRCE----QQCPQGHFGPGCEQLCQCQHGAACDHV-SGACTCPAGWRGTFCEH 857
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDE---CKELPYV 327
C + C +C NG C G +C+ RD C+
Sbjct: 858 ACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGC 917
Query: 328 CAGGECRNFNGGYVCECPAGWRFDKTAAVCV-DERKELCYDEWEAGRCHRARPLQLARPE 386
GG C G C CPAGW DK + C+ E C C A
Sbjct: 918 LNGGLCDPHTGR--CLCPAGWTGDKCQSPCLRGWFGEACAQRCS---CPPAAACHHVTGA 972
Query: 387 CCCSEGAAWGRYCER-CPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNT 445
C C G G CE+ CP G + + CR P +G C T
Sbjct: 973 CRCPPGFT-GSGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRC-PTGFLGTDCNLT 1030
Query: 446 DGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQ--CSPG-FTQG 502
CP G C A DP + G C R G C+ C F G
Sbjct: 1031 -------CPQGRFGPNCTHVCGCGQGAACDP-VTGTCLCPPGRAGVRCERGCPQNRFGVG 1082
Query: 503 PDQTCV--DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRV 560
+ TC + C SC+ T CP G AA + C C
Sbjct: 1083 CEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLEC----SCHNN--- 1135
Query: 561 CPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC 620
CE G+ C+C G+ + A ++ +C + G C + C
Sbjct: 1136 --STCEPATGT--CRCGPGFYGQACEHRRSGATCNL-DCRRGQ---FGPSC-----TLHC 1182
Query: 621 DCDAG--FEPSEDGTDCIDRRTG-TC 643
DC G +P C+D G TC
Sbjct: 1183 DCGGGADCDPVSGQCHCVDGYMGPTC 1208
Score = 70.9 bits (166), Expect = 2e-11
Identities = 38/119 (31%), Positives = 49/119 (41%), Gaps = 9/119 (7%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLC-HN 797
DVDEC G C PG + C C PG+R C ++ CA+ C C
Sbjct: 73 DVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQL 132
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
T + C CR G++L EDG +C C +C C G C C GY+ D
Sbjct: 133 TITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAAD 191
Score = 65.3 bits (152), Expect = 9e-10
Identities = 160/630 (25%), Positives = 214/630 (33%), Gaps = 97/630 (15%)
Query: 70 ECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCR-DV--DECSWGRPPCRGMAQ 125
+C + C+ G TC G C C G+ + C D CS+ C+
Sbjct: 431 DCSLTCDDCRNGGTCLLGLDG--CDCPEGWTGLICNETCPPDTFGKNCSFSCS-CQNGGT 487
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECED---VDECGDQRIC-DHGDCRNTIGSYRCECKPG 181
C ++ GA CRCPPG T D C C + C + G C G+ C C PG
Sbjct: 488 CDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGA--CLCDPG 543
Query: 182 YTLR-----------ENVCRDVDECSRPR-PVC--RNGTCENLPG--AYLC--HCDDGFK 223
R C + +C +P C R+G+C G C C+ G+
Sbjct: 544 LYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGY- 602
Query: 224 AGPNNDCVDVNECREGGMVCR--NGRC-RNTVGSFRCE-CAPGYTLTADGRNCRDVDECD 279
GP C C G+ C +G C + F+ E C + G NC C
Sbjct: 603 FGPG--CWQACTC-PVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCG 659
Query: 280 ELPHPC-GRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVC--AGGECRNF 336
PC G G C G +C G C + + C G C
Sbjct: 660 GA--PCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCL 717
Query: 337 NG--GYVCE--CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEG 392
G G C+ CPAGW C C+ G C A + C G
Sbjct: 718 PGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHP--ATGHCSCAPGWTGFSCQRACDTG 775
Query: 393 AAWGRYCE---RCPAP----DSAEFMRICQGGMGRPNLTQDLDECRVRP---DVCV---G 439
WG C C A D+ + +C+ G P Q + P +C G
Sbjct: 776 -HWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHG 834
Query: 440 GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT----CSNTRGGYECQC 495
C + G+ C CP G+ +C A LD R N T C G C C
Sbjct: 835 AACDHVSGA--CTCPAGWRGTFCEHAC-PAGFFGLDCRSACNCTAGAACDAVNG--SCLC 889
Query: 496 SPGFTQGPDQTCVDVDECAEGRASCTFR--CHN----TAGSFRCTCPYGYAVAADGVHCR 549
P +GP C + + RA C C N + RC CP G+ C
Sbjct: 890 -PAGRRGP--RCAEKCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCL 946
Query: 550 D--IDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDL 605
E + CP AC +V G+ C+CP G+ + Q CE+
Sbjct: 947 RGWFGEACAQRCSCPPAAACHHVTGA--CRCPPGFTGSGCEQGCPPGRYGPG-CEQLCGC 1003
Query: 606 CSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
+GG C G+ C C GF GTDC
Sbjct: 1004 LNGGSCDAATGA--CRCPTGFL----GTDC 1027
Score = 64.1 bits (149), Expect = 2e-09
Identities = 33/99 (33%), Positives = 43/99 (43%), Gaps = 3/99 (3%)
Query: 761 GRFRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
G + C G P AG+ DVDEC C C NT GSY C C+ G+ L D
Sbjct: 52 GCYPCHLGQAGYPVSAGDQRPDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRT 111
Query: 819 CRDVDECERDTHTCQQICSN-TEGSYECSCEDGYEKRGD 856
C ++ C CQ C T + C C G++ + D
Sbjct: 112 CLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQED 150
Score = 63.7 bits (148), Expect = 3e-09
Identities = 45/125 (36%), Positives = 55/125 (44%), Gaps = 14/125 (11%)
Query: 538 GYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDIN 597
GY V+A G D+DEC C H C N GSY+C+C G+R + DS C IN
Sbjct: 62 GYPVSA-GDQRPDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHT---DSRT-CLAIN 116
Query: 598 ECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDR-----RTGTCYR--SLVSG 650
C C T C C GF+ EDG C+ R R G+C +V G
Sbjct: 117 SCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRG 176
Query: 651 --RCE 653
RCE
Sbjct: 177 LARCE 181
Score = 47.2 bits (107), Expect = 2e-04
Identities = 24/59 (40%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 800 GSYDC-LCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA 857
G Y C L + GY + G DVDEC CQ C NT GSY C C+ G+ D+
Sbjct: 52 GCYPCHLGQAGYPVSA-GDQRPDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDS 109
>AY358895-1|AAQ89254.1| 915|Homo sapiens MATN2 protein.
Length = 915
Score = 182 bits (442), Expect = 6e-45
Identities = 121/393 (30%), Positives = 168/393 (42%), Gaps = 45/393 (11%)
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
C N GS+ C C GY L +D CR D C H C + C N G + C C +G
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ----LCVNVPGSFVCQCYSG 308
Query: 308 WKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
+ L G+RCV D C + C EC N +G Y+C+C G+ A+ DE+
Sbjct: 309 YALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGF------ALNPDEKT--- 358
Query: 366 YDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPN--L 423
C R L +P C C + + + R +G PN
Sbjct: 359 --------CTRINYCALNKPGCE-----------HECVNMEESYYCRCHRGYTLDPNGKT 399
Query: 424 TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT 483
+D C + C C+NT+ SF C+C +G+++ D +C D C L C +
Sbjct: 400 CSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGC-EYS 457
Query: 484 CSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVA 542
C N + CQC G D +TC +D CA G C C ++ SF C C GY +
Sbjct: 458 CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILR 517
Query: 543 ADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQ 602
DG CR D C C H C N SY C+C EG+R +D + C + C+
Sbjct: 518 EDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLA---EDGKR-CRRKDVCKST 573
Query: 603 EDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
C +C+N S++C C GF +EDG C
Sbjct: 574 HHGCEH-ICVNNGNSYICKCSEGFVLAEDGRRC 605
Score = 165 bits (402), Expect = 4e-40
Identities = 117/399 (29%), Positives = 167/399 (41%), Gaps = 43/399 (10%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
C + P + C C GY ++ CR D C+ C + CVN+PG+F C+C GY
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQL--CVNVPGSFVCQCYSGYA 310
Query: 143 LTPSLDECEDVDECGDQRI-CDHGDCRNTIGSYRCECKPGYTLR--ENVCRDVDECSRPR 199
L C VD C + C+H +C N GSY C+C G+ L E C ++ C+ +
Sbjct: 311 LAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTCTRINYCALNK 369
Query: 200 PVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCRNGRCRNTVGSFRCE 258
P C + C N+ +Y C C G+ PN C V+ C + C C NT SF C+
Sbjct: 370 PGCEH-ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQ 427
Query: 259 CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCV 316
C+ G+ + D + C VD C H C SC N + + C C G L G+ C
Sbjct: 428 CSEGFLINEDLKTCSRVDYCLLSDHGC----EYSCVNMDRSFACQCPEGHVLRSDGKTCA 483
Query: 317 DRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHR 376
D C + C C + +VC+C G+ + C RK++C + G C
Sbjct: 484 KLDSCALGDHGCE-HSCVSSEDSFVCQCFEGYILREDGKTC--RRKDVC-QAIDHG-CEH 538
Query: 377 ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDV 436
C C EG +RC D +C+ T E +
Sbjct: 539 ICVNSDDSYTCECLEGFRLAEDGKRCRRKD------VCKS-------THHGCE-----HI 580
Query: 437 CVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
C VN S+ C+C +G+VLA DG C E +D
Sbjct: 581 C-----VNNGNSYICKCSEGFVLAEDGRRCKKCTEGPID 614
Score = 162 bits (394), Expect = 4e-39
Identities = 110/369 (29%), Positives = 150/369 (40%), Gaps = 43/369 (11%)
Query: 278 CDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRN 335
C L H C C N G Y C C G+ L + C +D C + C C N
Sbjct: 242 CSTLEHNCAH----FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVN 296
Query: 336 FNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAW 395
G +VC+C +G+ + CV + C E C C C EG A
Sbjct: 297 VPGSFVCQCYSGYALAEDGKRCV--AVDYCASENHG--CEHECVNADGSYLCQCHEGFAL 352
Query: 396 GRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPD 455
PD RI + +P + CVN + S+ C C
Sbjct: 353 N--------PDEKTCTRINYCALNKPGCEHE---------------CVNMEESYYCRCHR 389
Query: 456 GYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECA 514
GY L P+G +C D CA C C NT + CQCS GF D +TC VD C
Sbjct: 390 GYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCL 448
Query: 515 EGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYIC 574
C + C N SF C CP G+ + +DG C +D C C H+C + S++C
Sbjct: 449 LSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVC 508
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTD 634
+C EGY ++ C + C+ + C +C+N+D S+ C+C GF +EDG
Sbjct: 509 QCFEGY----ILREDGKTCRRKDVCQAIDHGCE-HICVNSDDSYTCECLEGFRLAEDGKR 563
Query: 635 CIDRRTGTC 643
C RR C
Sbjct: 564 C--RRKDVC 570
Score = 146 bits (354), Expect = 3e-34
Identities = 103/366 (28%), Positives = 146/366 (39%), Gaps = 27/366 (7%)
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNE-CREGGMVCRNGRCRNTVGSFRCECAPGYTL 265
C N+PG+Y+C C G+ + + + C C C N GSF C+C GY L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKE 323
DG+ C VD C H C + C N +G Y C C G+ L + C + C
Sbjct: 312 AEDGKRCVAVDYCASENHGCEHE----CVNADGSYLCQCHEGFALNPDEKTCTRINYCAL 367
Query: 324 LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVC--VDER-------KELCYDEWEAGRC 374
C EC N Y C C G+ D C VD ++LC + ++ C
Sbjct: 368 NKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVC 426
Query: 375 HRARPLQLARPECCCSEG---AAWGRYCE-RCPAPDSAEFMRICQGGMGRPN--LTQDLD 428
+ + CS CE C D + + +G + R + LD
Sbjct: 427 QCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLD 486
Query: 429 ECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTR 488
C + C CV+++ SF C+C +GY+L DG +C D C C + C N+
Sbjct: 487 SCALGDHGCEHS-CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSD 544
Query: 489 GGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVH 547
Y C+C GF D + C D C C C N S+ C C G+ +A DG
Sbjct: 545 DSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRR 604
Query: 548 CRDIDE 553
C+ E
Sbjct: 605 CKKCTE 610
Score = 111 bits (266), Expect = 1e-23
Identities = 69/228 (30%), Positives = 99/228 (43%), Gaps = 12/228 (5%)
Query: 55 GEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS 114
G ++P +D C C+ C +T F C C G+ + C VD C
Sbjct: 390 GYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCL 448
Query: 115 WGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIG 172
C CVN+ +F C+CP G+ L C +D C GD C+H C ++
Sbjct: 449 LSDHGCE--YSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHG-CEHS-CVSSED 504
Query: 173 SYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK-AGPNND 229
S+ C+C GY LRE+ CR D C C + C N +Y C C +GF+ A
Sbjct: 505 SFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKR 563
Query: 230 CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE 277
C + C+ C + C N S+ C+C+ G+ L DGR C+ E
Sbjct: 564 CRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 610
Score = 93.5 bits (222), Expect = 3e-18
Identities = 37/95 (38%), Positives = 52/95 (54%), Gaps = 2/95 (2%)
Query: 759 APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 816
A G + C C G+ P + C ++ CA+ P C+ C N + SY C C GY LD +G
Sbjct: 338 ADGSYLCQCHEGFALNPDEKTCTRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNG 397
Query: 817 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C VD C + H C+Q+C NTE S+ C C +G+
Sbjct: 398 KTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGF 432
Score = 89.8 bits (213), Expect = 4e-17
Identities = 40/99 (40%), Positives = 51/99 (51%), Gaps = 2/99 (2%)
Query: 760 PGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG + C C GY + C D CA+ C+QLC N GS+ C C +GY L EDG
Sbjct: 257 PGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGK 316
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C VD C + H C+ C N +GSY C C +G+ D
Sbjct: 317 RCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPD 355
Score = 85.8 bits (203), Expect = 6e-16
Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 2/96 (2%)
Query: 763 FRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
F C C G+ R G+ CA +D CA+ C+ C +++ S+ C C GY L EDG CR
Sbjct: 465 FACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCR 524
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
D C+ H C+ IC N++ SY C C +G+ D
Sbjct: 525 RKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAED 560
Score = 85.4 bits (202), Expect = 8e-16
Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 2/96 (2%)
Query: 763 FRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
+ C C GY P G+ C+ VD CA + C+QLC NT+ S+ C C G+ ++ED C
Sbjct: 383 YYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCS 442
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
VD C H C+ C N + S+ C C +G+ R D
Sbjct: 443 RVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSD 478
Score = 85.0 bits (201), Expect = 1e-15
Identities = 37/91 (40%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Query: 763 FRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
F C C GY R G+ C D C C+ +C N+D SY C C G+ L EDG CR
Sbjct: 506 FVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCR 565
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
D C+ H C+ IC N SY C C +G+
Sbjct: 566 RKDVCKSTHHGCEHICVNNGNSYICKCSEGF 596
Score = 81.4 bits (192), Expect = 1e-14
Identities = 40/103 (38%), Positives = 49/103 (47%), Gaps = 4/103 (3%)
Query: 760 PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG F C C GY A G+ C VD CA C+ C N DGSY C C G+ L+ D
Sbjct: 298 PGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEK 357
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDAC 858
C ++ C + C+ C N E SY C C GY + G C
Sbjct: 358 TCTRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTC 400
Score = 73.3 bits (172), Expect = 3e-12
Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Query: 763 FRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
F C C G+ ++ C+ VD C + C+ C N D S+ C C G+ L DG C
Sbjct: 424 FVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCA 483
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
+D C H C+ C ++E S+ C C +GY R D
Sbjct: 484 KLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRED 519
Score = 72.5 bits (170), Expect = 6e-12
Identities = 31/78 (39%), Positives = 39/78 (50%), Gaps = 2/78 (2%)
Query: 784 CAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSY 843
C+ C C N GSY C C+ GY L+ D CR D C + H C+Q+C N GS+
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSF 301
Query: 844 ECSCEDGY--EKRGDACV 859
C C GY + G CV
Sbjct: 302 VCQCYSGYALAEDGKRCV 319
Score = 48.4 bits (110), Expect = 1e-04
Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Query: 763 FRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
+ C C G+R A G+ C D C C+ +C N SY C C G+ L EDG C+
Sbjct: 547 YTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCK 606
Query: 821 DVDE 824
E
Sbjct: 607 KCTE 610
>AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein.
Length = 1200
Score = 180 bits (439), Expect = 1e-44
Identities = 167/554 (30%), Positives = 235/554 (42%), Gaps = 99/554 (17%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
G+CH+ P+GF+C C G+ + D+DEC+ PC CV+ FEC CP
Sbjct: 360 GSCHEVPSGFECHCPSGWSGPTCA---LDIDECA--SNPCAAGGTCVDQVDGFECICPEQ 414
Query: 141 Y-RLTPSLDECEDVDECGDQRICDH-GDCRNTIGSYRCECKPGYTLRENVCR-DVDECSR 197
+ T L DV++C Q C H G C++ + Y+C C G+ R C + D+C+
Sbjct: 415 WVGATCQL----DVNDCRGQ--CQHGGTCKDLVNGYQCVCPRGFGGRH--CELERDKCA- 465
Query: 198 PRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSFR 256
P G CE+L + CHC GF +GP + VDV+ C CRNG RC N G +
Sbjct: 466 SSPCHSGGLCEDLADGFHCHCPQGF-SGPLCE-VDVDLCEPS--PCRNGARCYNLEGDYY 521
Query: 257 CECAPGY--------TLTADGRNCRDVDECDELPHP----------CGRDGNPSCTNTNG 298
C C + G CR +D C P CG G C + G
Sbjct: 522 CACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGR--CVSQPG 579
Query: 299 G-YECSCGAGWKLVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAA 355
G + C C +G+ G C + D+C P C GG C + + C CP+GW
Sbjct: 580 GNFSCICDSGF--TGTYCHENIDDCLGQP--CRNGGTCIDEVDAFRCFCPSGWE----GE 631
Query: 356 VCVDERKELCYDEWEAGRCH-RARPLQLARP-ECCCSEGAAW-GRYCE----RCPA---- 404
+C D C + CH R R L C C +G W G+ C +C A
Sbjct: 632 LC-DTNPNDCLPD----PCHSRGRCYDLVNDFYCACDDG--WKGKTCHSREFQCDAYTCS 684
Query: 405 -----PDSAEFMRIC--QGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDG 456
DS + R G G C P+ CV GG CV + SF C C DG
Sbjct: 685 NGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSC--LPNPCVNGGTCVGSGASFSCICRDG 742
Query: 457 YVLAPDGLSCV-DADECALDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECA 514
+ +G +C + ++C +P C N G C + + C+C+PGF GPD +++DEC
Sbjct: 743 W----EGRTCTHNTNDC--NPLPCYNGGICVDGVNWFRCECAPGFA-GPD-CRINIDECQ 794
Query: 515 EGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI----DECVQEPRVCPHACENVVG 570
+ C + +RC+CP G A G C+++ C PH V
Sbjct: 795 SSPCAYGATCVDEINGYRCSCPPGRA----GPRCQEVIGFGRSCWSRGTPFPHGSSWVED 850
Query: 571 SYICKCPEGYRRTS 584
C+C +G R S
Sbjct: 851 CNSCRCLDGRRDCS 864
Score = 173 bits (420), Expect = 3e-42
Identities = 155/579 (26%), Positives = 233/579 (40%), Gaps = 78/579 (13%)
Query: 69 DECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCV 127
DEC P C G+C + +QC C+ + LC +D++ C PC C+
Sbjct: 274 DECVPYPG-CVHGSCVEP---WQCNCETNWG----GLLCDKDLNYCG-SHHPCTNGGTCI 324
Query: 128 NL-PGAFECRCPPGYRLTPSLDECEDVDE-CGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
N P + C CP GY S CE + C + G C + C C G++
Sbjct: 325 NAEPDQYRCTCPDGY----SGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWS-G 379
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN 245
D+DEC+ P GTC + + C C + + +DVN+CR G
Sbjct: 380 PTCALDIDECA-SNPCAAGGTCVDQVDGFECICPEQWVGATCQ--LDVNDCR--GQCQHG 434
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
G C++ V ++C C G+ GR+C + D+C PC G C + G+ C C
Sbjct: 435 GTCKDLVNGYQCVCPRGF----GGRHCELERDKC--ASSPCHSGG--LCEDLADGFHCHC 486
Query: 305 GAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERK 362
G+ G C VD D C+ P C G C N G Y C CP + K +V +
Sbjct: 487 PQGFS--GPLCEVDVDLCEPSP--CRNGARCYNLEGDYYCACPDDFG-GKNCSV----PR 537
Query: 363 ELCYDEWEAGRCHRARPLQLARPECCCS-EGAAWGRYC---ERCPAPDSAEFMRICQGGM 418
E C G C R + + G A C RC + F IC G
Sbjct: 538 EPC----PGGAC---RVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGF 590
Query: 419 GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPR 477
+++D+C +P GG C++ +FRC CP G+ +G C + ++C DP
Sbjct: 591 TGTYCHENIDDCLGQP-CRNGGTCIDEVDAFRCFCPSGW----EGELCDTNPNDCLPDP- 644
Query: 478 ICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVD-ECAEGRASCTFRCHNTAGSFRCTCP 536
G C + + C C G+ +TC + +C S C+++ +FRC CP
Sbjct: 645 CHSRGRCYDLVNDFYCACDDGW---KGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACP 701
Query: 537 YGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDI 596
G+ + V C+ P V C S+ C C +G+ + +
Sbjct: 702 PGWKGSTCAV--AKNSSCLPNPCVNGGTCVGSGASFSCICRDGW-------EGRTCTHNT 752
Query: 597 NECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
N+C +GG+C++ F C+C GF G DC
Sbjct: 753 NDCNPL-PCYNGGICVDGVNWFRCECAPGFA----GPDC 786
Score = 151 bits (367), Expect = 8e-36
Identities = 140/461 (30%), Positives = 185/461 (40%), Gaps = 88/461 (19%)
Query: 65 TKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
T +D D Q GTC D G+QC C G+ H + D+C+ PC
Sbjct: 419 TCQLDVNDCRGQCQHGGTCKDLVNGYQCVCPRGF---GGRHCELERDKCA--SSPCHSGG 473
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGY- 182
C +L F C CP G+ S CE DVD C + C N G Y C C +
Sbjct: 474 LCEDLADGFHCHCPQGF----SGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFG 529
Query: 183 -----TLRE----NVCRDVDEC-SRPRP---------VC-RNGTCENLPGA-YLCHCDDG 221
RE CR +D C S P VC +G C + PG + C CD G
Sbjct: 530 GKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSG 589
Query: 222 FKAGPNNDCVDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDE 280
F ++ +D +C G CRN G C + V +FRC C G+ +G C D + D
Sbjct: 590 FTGTYCHENID--DCL--GQPCRNGGTCIDEVDAFRCFCPSGW----EGELC-DTNPNDC 640
Query: 281 LPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRD-ECKELPYVCA-GGECRNFNG 338
LP PC G C + + C+C GWK G+ C R+ +C Y C+ GG C +
Sbjct: 641 LPDPCHSRGR--CYDLVNDFYCACDDGWK--GKTCHSREFQCD--AYTCSNGGTCYDSGD 694
Query: 339 GYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRY 398
+ C CP GW+ + C + C P C + G G
Sbjct: 695 TFRCACPPGWK----GSTCAVAKNSSCL------------------PNPCVNGGTCVG-- 730
Query: 399 CERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGY 457
A F IC+ G T + ++C P C GG CV+ FRCEC G+
Sbjct: 731 -------SGASFSCICRDGWEGRTCTHNTNDCNPLP--CYNGGICVDGVNWFRCECAPGF 781
Query: 458 VLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPG 498
PD ++ DEC P G TC + GY C C PG
Sbjct: 782 A-GPD--CRINIDECQSSPCAYG-ATCVDEINGYRCSCPPG 818
Score = 149 bits (360), Expect = 5e-35
Identities = 146/539 (27%), Positives = 219/539 (40%), Gaps = 82/539 (15%)
Query: 113 CSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDE----CE-DVDECGDQRICDHGD- 166
CS+G R +CV PG C ++ + C+ D++ CG C +G
Sbjct: 264 CSYGWQG-RFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGT 322
Query: 167 CRNTI-GSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG 225
C N YRC C GY+ R C + P G+C +P + CHC G+ +G
Sbjct: 323 CINAEPDQYRCTCPDGYSGRN--CEKAEHACTSNPCANGGSCHEVPSGFECHCPSGW-SG 379
Query: 226 PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHP 284
P +D++EC G C + V F C C + G C+ DV++C
Sbjct: 380 P-TCALDIDECASNPCAA-GGTCVDQVDGFECICPEQWV----GATCQLDVNDC---RGQ 430
Query: 285 CGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCE 343
C G +C + GY+C C G+ GR C ++RD+C P +GG C + G+ C
Sbjct: 431 CQHGG--TCKDLVNGYQCVCPRGFG--GRHCELERDKCASSP-CHSGGLCEDLADGFHCH 485
Query: 344 CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHR-ARPLQLARPECCCSEGAAWGRYCE-- 400
CP G+ + +C E+ D E C AR L C G+ C
Sbjct: 486 CPQGF----SGPLC-----EVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVP 536
Query: 401 RCPAPDSAEFMRICQG-----GMGRPNLTQDLDECRVRPDVC-VGGRCVN-TDGSFRCEC 453
R P P A R+ G G G P VC GRCV+ G+F C C
Sbjct: 537 REPCPGGA--CRVIDGCGSDAGPGMPGTAAS--------GVCGPHGRCVSQPGGNFSCIC 586
Query: 454 PDGYVLAPDGLSC-VDADECALDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTC-VDV 510
G+ G C + D+C P C N GTC + + C C G+ +G + C +
Sbjct: 587 DSGFT----GTYCHENIDDCLGQP--CRNGGTCIDEVDAFRCFCPSGW-EG--ELCDTNP 637
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH--ACENV 568
++C RC++ F C C G+ H R+ +C + C + C +
Sbjct: 638 NDCLPDPCHSRGRCYDLVNDFYCACDDGW--KGKTCHSREF-QC--DAYTCSNGGTCYDS 692
Query: 569 VGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
++ C CP G++ ++ ++C N C +GG C+ + SF C C G+E
Sbjct: 693 GDTFRCACPPGWKGSTCAVAKNSSCLP-NPC------VNGGTCVGSGASFSCICRDGWE 744
Score = 50.0 bits (114), Expect = 4e-05
Identities = 31/99 (31%), Positives = 45/99 (45%), Gaps = 13/99 (13%)
Query: 760 PGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
P F C C G+ +G CA D+DECA P C + ++C+C + GA
Sbjct: 366 PSGFECHCPSGW--SGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWV----GAT 419
Query: 819 CR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKR 854
C+ DV++C CQ C + Y+C C G+ R
Sbjct: 420 CQLDVNDCRGQ---CQHGGTCKDLVNGYQCVCPRGFGGR 455
Score = 48.4 bits (110), Expect = 1e-04
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 8/92 (8%)
Query: 760 PGRFRCVCGPGYRPAGEVCADVDE-CAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
P ++RC C GY +G C + C P CH ++C C +G+ G
Sbjct: 328 PDQYRCTCPDGY--SGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGW----SGPT 381
Query: 819 CR-DVDECERDTHTCQQICSNTEGSYECSCED 849
C D+DEC + C + +EC C +
Sbjct: 382 CALDIDECASNPCAAGGTCVDQVDGFECICPE 413
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 9/92 (9%)
Query: 763 FRCVCGPGYRPAGEVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC- 819
FRC C PG++ G CA + P PC C + S+ C+CR G+E G C
Sbjct: 696 FRCACPPGWK--GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWE----GRTCT 749
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
+ ++C IC + + C C G+
Sbjct: 750 HNTNDCNPLPCYNGGICVDGVNWFRCECAPGF 781
Score = 46.4 bits (105), Expect = 4e-04
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 12/109 (11%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C + PG G F C+C G+ G C + +D+C +P C + ++ C C +G
Sbjct: 574 CVSQPG----GNFSCICDSGF--TGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSG 627
Query: 810 YELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
+E + N D C D + C + + C+C+DG+ +G C
Sbjct: 628 WEGELCDTNPND---CLPDPCHSRGRCYDLVNDFYCACDDGW--KGKTC 671
Score = 44.0 bits (99), Expect = 0.002
Identities = 45/173 (26%), Positives = 66/173 (38%), Gaps = 29/173 (16%)
Query: 478 ICGNGTCSNTRGGY----ECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRC 533
+C G C+ GG EC+CS G+ CV C G SC ++C
Sbjct: 244 VCKQG-CNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHG--SCV-------EPWQC 293
Query: 534 TCPYGYAVAADGVHC-RDIDEC-VQEPRVCPHACENVV-GSYICKCPEGYRRTSAPQDSE 590
C + G+ C +D++ C P C N Y C CP+GY + + +E
Sbjct: 294 NCETNWG----GLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNC-EKAE 348
Query: 591 NACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
+AC N C +GG C F C C +G+ D + + C
Sbjct: 349 HACTS-NPC------ANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPC 394
Score = 41.9 bits (94), Expect = 0.009
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 14/100 (14%)
Query: 763 FRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC 819
F C+C G+ G C + ++C P PC +C + + C C G+ G +C
Sbjct: 735 FSCICRDGWE--GRTCTHNTNDC--NPLPCYNGGICVDGVNWFRCECAPGFA----GPDC 786
Query: 820 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
R ++DEC+ C + Y CSC G + G C
Sbjct: 787 RINIDECQSSPCAYGATCVDEINGYRCSCPPG--RAGPRC 824
Score = 41.1 bits (92), Expect = 0.016
Identities = 40/134 (29%), Positives = 56/134 (41%), Gaps = 36/134 (26%)
Query: 749 DECAAIP----GLC---APGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQ--LCHNT 798
D+CA+ P GLC A G F C C G+ +G +C DVD C P PC C+N
Sbjct: 462 DKCASSPCHSGGLCEDLADG-FHCHCPQGF--SGPLCEVDVDLC--EPSPCRNGARCYNL 516
Query: 799 DGSYDCLCRTGY-----ELDED---GANCRDVDECERDT------HTCQQIC-------S 837
+G Y C C + + + G CR +D C D +C S
Sbjct: 517 EGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVS 576
Query: 838 NTEGSYECSCEDGY 851
G++ C C+ G+
Sbjct: 577 QPGGNFSCICDSGF 590
Score = 35.9 bits (79), Expect = 0.61
Identities = 22/95 (23%), Positives = 39/95 (41%), Gaps = 9/95 (9%)
Query: 763 FRCVCGPGYRPAGEVCADVD-ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 821
F C C G++ G+ C + +C C+++ ++ C C G++ G+ C
Sbjct: 658 FYCACDDGWK--GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWK----GSTCAV 711
Query: 822 VDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKR 854
+ C C + S+ C C DG+E R
Sbjct: 712 AKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGR 746
Score = 35.1 bits (77), Expect = 1.1
Identities = 34/109 (31%), Positives = 41/109 (37%), Gaps = 20/109 (18%)
Query: 751 CAAIPGLCA-PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTG 809
C + G C PG RC Y G C DEC P C + C C T
Sbjct: 249 CNLLHGGCTVPGECRC----SYGWQGRFC---DECVPYPGCVHGSCVEP---WQCNCETN 298
Query: 810 YELDEDGANC-RDVDECERDTHTCQQ--ICSNTE-GSYECSCEDGYEKR 854
+ G C +D++ C H C C N E Y C+C DGY R
Sbjct: 299 W----GGLLCDKDLNYCGSH-HPCTNGGTCINAEPDQYRCTCPDGYSGR 342
>DQ217942-1|ABB70739.1| 886|Homo sapiens EGF-like module containing
mucin-like hormone receptor-like 1 protein.
Length = 886
Score = 180 bits (438), Expect = 2e-44
Identities = 95/259 (36%), Positives = 126/259 (48%), Gaps = 36/259 (13%)
Query: 82 TCHDTPTGFQCGCDHGYEHDN-TSHL------CRDVDECSWGRPPCRGMAQCVNLPGAFE 134
TC +T + C C G+ N +H C+D+DECS PC + C NL G ++
Sbjct: 46 TCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYK 105
Query: 135 CRCPPGYRLTPSLD---------ECEDVDECGDQRIC-DHGDCRNTIGSYRCECKPGYTL 184
C C G+ D C D++EC +C +H DC N++GSY C C+ G+
Sbjct: 106 CSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFIS 165
Query: 185 RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA--------GPNNDCVDVNEC 236
R + C DVDEC+ PR + TC N G Y C C+ GF++ G C D++EC
Sbjct: 166 RNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDEC 225
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGY-------TLTADGRNCRDVDECDELPHPCGRDG 289
E M N C NT GS+ C C PG+ T G CRD+DEC + P CG
Sbjct: 226 TE--MCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCG--P 281
Query: 290 NPSCTNTNGGYECSCGAGW 308
N CTN G Y C C AG+
Sbjct: 282 NSICTNALGSYSCGCIAGF 300
Score = 141 bits (341), Expect = 1e-32
Identities = 84/255 (32%), Positives = 113/255 (44%), Gaps = 34/255 (13%)
Query: 66 KPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHL---------CRDVDECSW 115
K IDEC PQ C P + C + ++C C G+ + C D++EC
Sbjct: 79 KDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLT 138
Query: 116 GRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRIC-DHGDCRNTIGSY 174
C + CVN G++ C C G+ S CEDVDEC D R C +H C NT+G+Y
Sbjct: 139 SSV-CPEHSDCVNSMGSYSCSCQVGFISRNST--CEDVDECADPRACPEHATCNNTVGNY 195
Query: 175 RCECKPGYTLREN---------VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA- 224
C C PG+ C D+DEC+ P+ N TC N PG+Y C C GF
Sbjct: 196 SCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGFAPS 253
Query: 225 -GPNN------DCVDVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTLTADGRNCRDVD 276
G N +C D++ECR+ C N C N +GS+ C C G+ +G
Sbjct: 254 NGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNF 313
Query: 277 ECDELPHPCGRDGNP 291
C + C D P
Sbjct: 314 SCQRVLFKCKEDVIP 328
Score = 140 bits (339), Expect = 2e-32
Identities = 80/234 (34%), Positives = 110/234 (47%), Gaps = 30/234 (12%)
Query: 425 QDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLA---------PDGLSCVDADECAL 474
+D+DEC P C C N G ++C C DG+ P SC D +EC L
Sbjct: 79 KDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-L 137
Query: 475 DPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFR 532
+C + C N+ G Y C C GF + TC DVDECA+ RA C+NT G++
Sbjct: 138 TSSVCPEHSDCVNSMGSYSCSCQVGFI-SRNSTCEDVDECADPRACPEHATCNNTVGNYS 196
Query: 533 CTCPYGYAVAADGV-------HCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRT 583
C C G+ ++ + C DIDEC + +CP C N GSY C C G+ +
Sbjct: 197 CFCNPGFESSSGHLSFQGLKASCEDIDECTE---MCPINSTCTNTPGSYFCTCHPGFAPS 253
Query: 584 SAP---QDSENACEDINECEEQEDLCS-GGVCINTDGSFLCDCDAGFEPSEDGT 633
+ D C DI+EC + C +C N GS+ C C AGF P+ +G+
Sbjct: 254 NGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGS 307
Score = 135 bits (327), Expect = 5e-31
Identities = 79/221 (35%), Positives = 111/221 (50%), Gaps = 29/221 (13%)
Query: 442 CVNTDGSFRCECPDGYVLA-------PDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
C NT S+ C C G++ + G+ C D DEC+ P+ CG N +C N G Y+C
Sbjct: 47 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKC 106
Query: 494 QCSPGFTQ--GPDQ--------TCVDVDECAEGRASCTFR-CHNTAGSFRCTCPYGYAVA 542
C GF+ G D +C D++EC C N+ GS+ C+C G+ ++
Sbjct: 107 SCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGF-IS 165
Query: 543 ADGVHCRDIDECVQEPRVCP-HA-CENVVGSYICKCPEGYRRTSAP---QDSENACEDIN 597
+ C D+DEC +PR CP HA C N VG+Y C C G+ +S Q + +CEDI+
Sbjct: 166 RNST-CEDVDECA-DPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDID 223
Query: 598 ECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDR 638
EC E + S C NT GS+ C C GF PS + D+
Sbjct: 224 ECTEMCPINS--TCTNTPGSYFCTCHPGFAPSNGQLNFTDQ 262
Score = 128 bits (309), Expect = 8e-29
Identities = 101/307 (32%), Positives = 138/307 (44%), Gaps = 39/307 (12%)
Query: 319 DECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRAR 378
+ C++ A C N Y C C G+ D C D E C ++
Sbjct: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR-CKDIDE---CSQSP 88
Query: 379 PLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRP-NLT-QDLDECRVRPDV 436
Q P C + GRY +C D G+P N + D++EC + V
Sbjct: 89 --QPCGPNSSCKNLS--GRY--KCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-LTSSV 141
Query: 437 CVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQ 494
C CVN+ GS+ C C G++ +C D DECA DPR C + TC+NT G Y C
Sbjct: 142 CPEHSDCVNSMGSYSCSCQVGFISRNS--TCEDVDECA-DPRACPEHATCNNTVGNYSCF 198
Query: 495 CSPGFT--------QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA------ 540
C+PGF QG +C D+DEC E C NT GS+ CTC G+A
Sbjct: 199 CNPGFESSSGHLSFQGLKASCEDIDECTE-MCPINSTCTNTPGSYFCTCHPGFAPSNGQL 257
Query: 541 -VAADGVHCRDIDECVQEPRVC-PHA-CENVVGSYICKCPEGYRRT--SAPQDSENACED 595
GV CRDIDEC Q+P C P++ C N +GSY C C G+ + +D +C+
Sbjct: 258 NFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQR 317
Query: 596 I-NECEE 601
+ +C+E
Sbjct: 318 VLFKCKE 324
Score = 128 bits (308), Expect = 1e-28
Identities = 74/225 (32%), Positives = 103/225 (45%), Gaps = 37/225 (16%)
Query: 154 DECGDQRICD-HGDCRNTIGSYRCECKPGYTLRENV---------CRDVDECSR-PRPVC 202
+ C D +C + C NT+ SY C CK G+ C+D+DECS+ P+P
Sbjct: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
Query: 203 RNGTCENLPGAYLCHCDDGFKAGPNND----------CVDVNECREGGMVCRNGRCRNTV 252
N +C+NL G Y C C DGF + ND C D+NEC + + C N++
Sbjct: 93 PNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSM 152
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL-- 310
GS+ C C G+ + C DVDEC + P C + +C NT G Y C C G++
Sbjct: 153 GSYSCSCQVGF--ISRNSTCEDVDECAD-PRACPE--HATCNNTVGNYSCFCNPGFESSS 207
Query: 311 -------VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
+ C D DEC E+ + C N G Y C C G+
Sbjct: 208 GHLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGF 250
Score = 126 bits (305), Expect = 3e-28
Identities = 82/266 (30%), Positives = 115/266 (43%), Gaps = 43/266 (16%)
Query: 120 CRGMAQCVNLPGAFECRCPPGYRLTPSLD-------ECEDVDECGD--QRICDHGDCRNT 170
C A C N ++ C C G+ + + C+D+DEC Q + C+N
Sbjct: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNL 100
Query: 171 IGSYRCECKPGYTLREN-----------VCRDVDECSRPRPVCRNGTCENLPGAYLCHCD 219
G Y+C C G++ C D++EC + C N G+Y C C
Sbjct: 101 SGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQ 160
Query: 220 DGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYT-----LTADG--RNC 272
GF N+ C DV+EC + + C NTVG++ C C PG+ L+ G +C
Sbjct: 161 VGF-ISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASC 219
Query: 273 RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL---------VGRRCVDRDECKE 323
D+DEC E+ C N +CTNT G Y C+C G+ G C D DEC++
Sbjct: 220 EDIDECTEM---C--PINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQ 274
Query: 324 LPYVCAGGE-CRNFNGGYVCECPAGW 348
P C C N G Y C C AG+
Sbjct: 275 DPSTCGPNSICTNALGSYSCGCIAGF 300
Score = 97.9 bits (233), Expect = 1e-19
Identities = 82/297 (27%), Positives = 113/297 (38%), Gaps = 43/297 (14%)
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG--------PNNDCVDVNECRE 238
N CRD C TC N +Y C C GF + P C D++EC +
Sbjct: 33 NNCRDSTLCPA------YATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQ 86
Query: 239 GGMVCR-NGRCRNTVGSFRCECAPGYTLTAD-----GR----NCRDVDECDELPHPCGRD 288
C N C+N G ++C C G++ G+ +C D++EC C
Sbjct: 87 SPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-LTSSVCPEH 145
Query: 289 GNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVC-AGGECRNFNGGYVCECPAG 347
+ C N+ G Y CSC G+ C D DEC + P C C N G Y C C G
Sbjct: 146 SD--CVNSMGSYSCSCQVGFISRNSTCEDVDECAD-PRACPEHATCNNTVGNYSCFCNPG 202
Query: 348 WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS 407
+ + + K C D C P+ C + ++ C AP +
Sbjct: 203 FE-SSSGHLSFQGLKASCED---IDECTEMCPIN----STCTNTPGSYFCTCHPGFAPSN 254
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDG 463
+ QG R D+DECR P C C N GS+ C C G+ P+G
Sbjct: 255 GQLNFTDQGVECR-----DIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
Score = 92.7 bits (220), Expect = 5e-18
Identities = 58/177 (32%), Positives = 82/177 (46%), Gaps = 29/177 (16%)
Query: 475 DPRIC-GNGTCSNTRGGYECQCSPGFTQG--------PDQTCVDVDECAEGRASC--TFR 523
D +C TC+NT Y C C GF P C D+DEC++ C
Sbjct: 37 DSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSS 96
Query: 524 CHNTAGSFRCTCPYGYA--VAADGV-------HCRDIDECVQEPRVCP-HA-CENVVGSY 572
C N +G ++C+C G++ D V C DI+EC+ VCP H+ C N +GSY
Sbjct: 97 CKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS-VCPEHSDCVNSMGSY 155
Query: 573 ICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPS 629
C C G+ ++ CED++EC + C NT G++ C C+ GFE S
Sbjct: 156 SCSCQVGFISRNS------TCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESS 206
Score = 81.8 bits (193), Expect = 9e-15
Identities = 49/130 (37%), Positives = 61/130 (46%), Gaps = 26/130 (20%)
Query: 747 DVDECA---AIP--GLC--APGRFRCVCGPGYRPA-GEV--------CADVDECAVRPPP 790
DVDECA A P C G + C C PG+ + G + C D+DEC P
Sbjct: 172 DVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT-EMCP 230
Query: 791 CDQLCHNTDGSYDCLCRTGY-------ELDEDGANCRDVDECERDTHTC--QQICSNTEG 841
+ C NT GSY C C G+ + G CRD+DEC +D TC IC+N G
Sbjct: 231 INSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALG 290
Query: 842 SYECSCEDGY 851
SY C C G+
Sbjct: 291 SYSCGCIAGF 300
Score = 76.2 bits (179), Expect = 5e-13
Identities = 41/101 (40%), Positives = 51/101 (50%), Gaps = 13/101 (12%)
Query: 761 GRFRCVCGPGYRPAGEVCADVDECA-VRPPPCDQLCHNTDGSYDCLCRTGYE-----LDE 814
G + C C G+ C DVDECA R P C+NT G+Y C C G+E L
Sbjct: 153 GSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSF 212
Query: 815 DG--ANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGY 851
G A+C D+DEC T C C+NT GSY C+C G+
Sbjct: 213 QGLKASCEDIDEC---TEMCPINSTCTNTPGSYFCTCHPGF 250
Score = 72.9 bits (171), Expect = 4e-12
Identities = 45/130 (34%), Positives = 62/130 (47%), Gaps = 29/130 (22%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGY-----------RPAGEVCADVDEC--- 784
D+DEC+ P C P GR++C C G+ +P C D++EC
Sbjct: 80 DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTS 139
Query: 785 AVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGS 842
+V P D C N+ GSY C C+ G+ + C DVDEC D C + C+NT G+
Sbjct: 140 SVCPEHSD--CVNSMGSYSCSCQVGFI--SRNSTCEDVDECA-DPRACPEHATCNNTVGN 194
Query: 843 YECSCEDGYE 852
Y C C G+E
Sbjct: 195 YSCFCNPGFE 204
Score = 61.3 bits (142), Expect = 1e-08
Identities = 32/101 (31%), Positives = 46/101 (45%), Gaps = 14/101 (13%)
Query: 771 YRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGA---------NC 819
++ G C D+DEC+ P PC + C N G Y C C G+ +C
Sbjct: 71 FKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSC 130
Query: 820 RDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDAC 858
D++EC + C + C N+ GSY CSC+ G+ R C
Sbjct: 131 TDINECLTSS-VCPEHSDCVNSMGSYSCSCQVGFISRNSTC 170
Score = 58.0 bits (134), Expect = 1e-07
Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 16/104 (15%)
Query: 747 DVDECAA---IPGLCA--PGRFRCVCGPGYRPA---------GEVCADVDECAVRPPPC- 791
D+DEC I C PG + C C PG+ P+ G C D+DEC P C
Sbjct: 221 DIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCG 280
Query: 792 -DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ 834
+ +C N GSY C C G+ + +G+ C+R C++
Sbjct: 281 PNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKE 324
Score = 56.0 bits (129), Expect = 5e-07
Identities = 29/86 (33%), Positives = 37/86 (43%), Gaps = 14/86 (16%)
Query: 775 GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY-------ELDEDGANCRDVDECER 827
G C D C P C NT SY C C+ G+ + G C+D+DEC +
Sbjct: 32 GNNCRDSTLC-----PAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQ 86
Query: 828 DTHTC--QQICSNTEGSYECSCEDGY 851
C C N G Y+CSC DG+
Sbjct: 87 SPQPCGPNSSCKNLSGRYKCSCLDGF 112
>BC059395-1|AAH59395.1| 821|Homo sapiens EMR1 protein protein.
Length = 821
Score = 180 bits (438), Expect = 2e-44
Identities = 95/259 (36%), Positives = 126/259 (48%), Gaps = 36/259 (13%)
Query: 82 TCHDTPTGFQCGCDHGYEHDN-TSHL------CRDVDECSWGRPPCRGMAQCVNLPGAFE 134
TC +T + C C G+ N +H C+D+DECS PC + C NL G ++
Sbjct: 46 TCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYK 105
Query: 135 CRCPPGYRLTPSLD---------ECEDVDECGDQRIC-DHGDCRNTIGSYRCECKPGYTL 184
C C G+ D C D++EC +C +H DC N++GSY C C+ G+
Sbjct: 106 CSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFIS 165
Query: 185 RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA--------GPNNDCVDVNEC 236
R + C DVDEC+ PR + TC N G Y C C+ GF++ G C D++EC
Sbjct: 166 RNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDEC 225
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGY-------TLTADGRNCRDVDECDELPHPCGRDG 289
E M N C NT GS+ C C PG+ T G CRD+DEC + P CG
Sbjct: 226 TE--MCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCG--P 281
Query: 290 NPSCTNTNGGYECSCGAGW 308
N CTN G Y C C AG+
Sbjct: 282 NSICTNALGSYSCGCIAGF 300
Score = 141 bits (341), Expect = 1e-32
Identities = 84/255 (32%), Positives = 113/255 (44%), Gaps = 34/255 (13%)
Query: 66 KPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHL---------CRDVDECSW 115
K IDEC PQ C P + C + ++C C G+ + C D++EC
Sbjct: 79 KDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLT 138
Query: 116 GRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRIC-DHGDCRNTIGSY 174
C + CVN G++ C C G+ S CEDVDEC D R C +H C NT+G+Y
Sbjct: 139 SSV-CPEHSDCVNSMGSYSCSCQVGFISRNST--CEDVDECADPRACPEHATCNNTVGNY 195
Query: 175 RCECKPGYTLREN---------VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA- 224
C C PG+ C D+DEC+ P+ N TC N PG+Y C C GF
Sbjct: 196 SCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGFAPS 253
Query: 225 -GPNN------DCVDVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTLTADGRNCRDVD 276
G N +C D++ECR+ C N C N +GS+ C C G+ +G
Sbjct: 254 NGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNF 313
Query: 277 ECDELPHPCGRDGNP 291
C + C D P
Sbjct: 314 SCQRVLFKCKEDVIP 328
Score = 140 bits (339), Expect = 2e-32
Identities = 80/234 (34%), Positives = 110/234 (47%), Gaps = 30/234 (12%)
Query: 425 QDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLA---------PDGLSCVDADECAL 474
+D+DEC P C C N G ++C C DG+ P SC D +EC L
Sbjct: 79 KDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-L 137
Query: 475 DPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFR 532
+C + C N+ G Y C C GF + TC DVDECA+ RA C+NT G++
Sbjct: 138 TSSVCPEHSDCVNSMGSYSCSCQVGFI-SRNSTCEDVDECADPRACPEHATCNNTVGNYS 196
Query: 533 CTCPYGYAVAADGV-------HCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRT 583
C C G+ ++ + C DIDEC + +CP C N GSY C C G+ +
Sbjct: 197 CFCNPGFESSSGHLSFQGLKASCEDIDECTE---MCPINSTCTNTPGSYFCTCHPGFAPS 253
Query: 584 SAP---QDSENACEDINECEEQEDLCS-GGVCINTDGSFLCDCDAGFEPSEDGT 633
+ D C DI+EC + C +C N GS+ C C AGF P+ +G+
Sbjct: 254 NGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGS 307
Score = 135 bits (327), Expect = 5e-31
Identities = 79/221 (35%), Positives = 111/221 (50%), Gaps = 29/221 (13%)
Query: 442 CVNTDGSFRCECPDGYVLA-------PDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
C NT S+ C C G++ + G+ C D DEC+ P+ CG N +C N G Y+C
Sbjct: 47 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKC 106
Query: 494 QCSPGFTQ--GPDQ--------TCVDVDECAEGRASCTFR-CHNTAGSFRCTCPYGYAVA 542
C GF+ G D +C D++EC C N+ GS+ C+C G+ ++
Sbjct: 107 SCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGF-IS 165
Query: 543 ADGVHCRDIDECVQEPRVCP-HA-CENVVGSYICKCPEGYRRTSAP---QDSENACEDIN 597
+ C D+DEC +PR CP HA C N VG+Y C C G+ +S Q + +CEDI+
Sbjct: 166 RNST-CEDVDECA-DPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDID 223
Query: 598 ECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDR 638
EC E + S C NT GS+ C C GF PS + D+
Sbjct: 224 ECTEMCPINS--TCTNTPGSYFCTCHPGFAPSNGQLNFTDQ 262
Score = 128 bits (309), Expect = 8e-29
Identities = 101/307 (32%), Positives = 138/307 (44%), Gaps = 39/307 (12%)
Query: 319 DECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRAR 378
+ C++ A C N Y C C G+ D C D E C ++
Sbjct: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR-CKDIDE---CSQSP 88
Query: 379 PLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRP-NLT-QDLDECRVRPDV 436
Q P C + GRY +C D G+P N + D++EC + V
Sbjct: 89 --QPCGPNSSCKNLS--GRY--KCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-LTSSV 141
Query: 437 CVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQ 494
C CVN+ GS+ C C G++ +C D DECA DPR C + TC+NT G Y C
Sbjct: 142 CPEHSDCVNSMGSYSCSCQVGFISRNS--TCEDVDECA-DPRACPEHATCNNTVGNYSCF 198
Query: 495 CSPGFT--------QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA------ 540
C+PGF QG +C D+DEC E C NT GS+ CTC G+A
Sbjct: 199 CNPGFESSSGHLSFQGLKASCEDIDECTE-MCPINSTCTNTPGSYFCTCHPGFAPSNGQL 257
Query: 541 -VAADGVHCRDIDECVQEPRVC-PHA-CENVVGSYICKCPEGYRRT--SAPQDSENACED 595
GV CRDIDEC Q+P C P++ C N +GSY C C G+ + +D +C+
Sbjct: 258 NFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQR 317
Query: 596 I-NECEE 601
+ +C+E
Sbjct: 318 VLFKCKE 324
Score = 128 bits (308), Expect = 1e-28
Identities = 74/225 (32%), Positives = 103/225 (45%), Gaps = 37/225 (16%)
Query: 154 DECGDQRICD-HGDCRNTIGSYRCECKPGYTLRENV---------CRDVDECSR-PRPVC 202
+ C D +C + C NT+ SY C CK G+ C+D+DECS+ P+P
Sbjct: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
Query: 203 RNGTCENLPGAYLCHCDDGFKAGPNND----------CVDVNECREGGMVCRNGRCRNTV 252
N +C+NL G Y C C DGF + ND C D+NEC + + C N++
Sbjct: 93 PNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSM 152
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL-- 310
GS+ C C G+ + C DVDEC + P C + +C NT G Y C C G++
Sbjct: 153 GSYSCSCQVGF--ISRNSTCEDVDECAD-PRACPE--HATCNNTVGNYSCFCNPGFESSS 207
Query: 311 -------VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
+ C D DEC E+ + C N G Y C C G+
Sbjct: 208 GHLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGF 250
Score = 126 bits (305), Expect = 3e-28
Identities = 82/266 (30%), Positives = 115/266 (43%), Gaps = 43/266 (16%)
Query: 120 CRGMAQCVNLPGAFECRCPPGYRLTPSLD-------ECEDVDECGD--QRICDHGDCRNT 170
C A C N ++ C C G+ + + C+D+DEC Q + C+N
Sbjct: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNL 100
Query: 171 IGSYRCECKPGYTLREN-----------VCRDVDECSRPRPVCRNGTCENLPGAYLCHCD 219
G Y+C C G++ C D++EC + C N G+Y C C
Sbjct: 101 SGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQ 160
Query: 220 DGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYT-----LTADG--RNC 272
GF N+ C DV+EC + + C NTVG++ C C PG+ L+ G +C
Sbjct: 161 VGF-ISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASC 219
Query: 273 RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL---------VGRRCVDRDECKE 323
D+DEC E+ C N +CTNT G Y C+C G+ G C D DEC++
Sbjct: 220 EDIDECTEM---C--PINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQ 274
Query: 324 LPYVCAGGE-CRNFNGGYVCECPAGW 348
P C C N G Y C C AG+
Sbjct: 275 DPSTCGPNSICTNALGSYSCGCIAGF 300
Score = 97.9 bits (233), Expect = 1e-19
Identities = 82/297 (27%), Positives = 113/297 (38%), Gaps = 43/297 (14%)
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG--------PNNDCVDVNECRE 238
N CRD C TC N +Y C C GF + P C D++EC +
Sbjct: 33 NNCRDSTLCPA------YATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQ 86
Query: 239 GGMVCR-NGRCRNTVGSFRCECAPGYTLTAD-----GR----NCRDVDECDELPHPCGRD 288
C N C+N G ++C C G++ G+ +C D++EC C
Sbjct: 87 SPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-LTSSVCPEH 145
Query: 289 GNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVC-AGGECRNFNGGYVCECPAG 347
+ C N+ G Y CSC G+ C D DEC + P C C N G Y C C G
Sbjct: 146 SD--CVNSMGSYSCSCQVGFISRNSTCEDVDECAD-PRACPEHATCNNTVGNYSCFCNPG 202
Query: 348 WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS 407
+ + + K C D C P+ C + ++ C AP +
Sbjct: 203 FE-SSSGHLSFQGLKASCED---IDECTEMCPIN----STCTNTPGSYFCTCHPGFAPSN 254
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDG 463
+ QG R D+DECR P C C N GS+ C C G+ P+G
Sbjct: 255 GQLNFTDQGVECR-----DIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
Score = 92.7 bits (220), Expect = 5e-18
Identities = 58/177 (32%), Positives = 82/177 (46%), Gaps = 29/177 (16%)
Query: 475 DPRIC-GNGTCSNTRGGYECQCSPGFTQG--------PDQTCVDVDECAEGRASC--TFR 523
D +C TC+NT Y C C GF P C D+DEC++ C
Sbjct: 37 DSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSS 96
Query: 524 CHNTAGSFRCTCPYGYA--VAADGV-------HCRDIDECVQEPRVCP-HA-CENVVGSY 572
C N +G ++C+C G++ D V C DI+EC+ VCP H+ C N +GSY
Sbjct: 97 CKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS-VCPEHSDCVNSMGSY 155
Query: 573 ICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPS 629
C C G+ ++ CED++EC + C NT G++ C C+ GFE S
Sbjct: 156 SCSCQVGFISRNS------TCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESS 206
Score = 81.8 bits (193), Expect = 9e-15
Identities = 49/130 (37%), Positives = 61/130 (46%), Gaps = 26/130 (20%)
Query: 747 DVDECA---AIP--GLC--APGRFRCVCGPGYRPA-GEV--------CADVDECAVRPPP 790
DVDECA A P C G + C C PG+ + G + C D+DEC P
Sbjct: 172 DVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT-EMCP 230
Query: 791 CDQLCHNTDGSYDCLCRTGY-------ELDEDGANCRDVDECERDTHTC--QQICSNTEG 841
+ C NT GSY C C G+ + G CRD+DEC +D TC IC+N G
Sbjct: 231 INSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALG 290
Query: 842 SYECSCEDGY 851
SY C C G+
Sbjct: 291 SYSCGCIAGF 300
Score = 76.2 bits (179), Expect = 5e-13
Identities = 41/101 (40%), Positives = 51/101 (50%), Gaps = 13/101 (12%)
Query: 761 GRFRCVCGPGYRPAGEVCADVDECA-VRPPPCDQLCHNTDGSYDCLCRTGYE-----LDE 814
G + C C G+ C DVDECA R P C+NT G+Y C C G+E L
Sbjct: 153 GSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSF 212
Query: 815 DG--ANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGY 851
G A+C D+DEC T C C+NT GSY C+C G+
Sbjct: 213 QGLKASCEDIDEC---TEMCPINSTCTNTPGSYFCTCHPGF 250
Score = 72.9 bits (171), Expect = 4e-12
Identities = 45/130 (34%), Positives = 62/130 (47%), Gaps = 29/130 (22%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGY-----------RPAGEVCADVDEC--- 784
D+DEC+ P C P GR++C C G+ +P C D++EC
Sbjct: 80 DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTS 139
Query: 785 AVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGS 842
+V P D C N+ GSY C C+ G+ + C DVDEC D C + C+NT G+
Sbjct: 140 SVCPEHSD--CVNSMGSYSCSCQVGFI--SRNSTCEDVDECA-DPRACPEHATCNNTVGN 194
Query: 843 YECSCEDGYE 852
Y C C G+E
Sbjct: 195 YSCFCNPGFE 204
Score = 61.3 bits (142), Expect = 1e-08
Identities = 32/101 (31%), Positives = 46/101 (45%), Gaps = 14/101 (13%)
Query: 771 YRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGA---------NC 819
++ G C D+DEC+ P PC + C N G Y C C G+ +C
Sbjct: 71 FKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSC 130
Query: 820 RDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDAC 858
D++EC + C + C N+ GSY CSC+ G+ R C
Sbjct: 131 TDINECLTSS-VCPEHSDCVNSMGSYSCSCQVGFISRNSTC 170
Score = 58.0 bits (134), Expect = 1e-07
Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 16/104 (15%)
Query: 747 DVDECAA---IPGLCA--PGRFRCVCGPGYRPA---------GEVCADVDECAVRPPPC- 791
D+DEC I C PG + C C PG+ P+ G C D+DEC P C
Sbjct: 221 DIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCG 280
Query: 792 -DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ 834
+ +C N GSY C C G+ + +G+ C+R C++
Sbjct: 281 PNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKE 324
Score = 56.0 bits (129), Expect = 5e-07
Identities = 29/86 (33%), Positives = 37/86 (43%), Gaps = 14/86 (16%)
Query: 775 GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY-------ELDEDGANCRDVDECER 827
G C D C P C NT SY C C+ G+ + G C+D+DEC +
Sbjct: 32 GNNCRDSTLC-----PAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQ 86
Query: 828 DTHTC--QQICSNTEGSYECSCEDGY 851
C C N G Y+CSC DG+
Sbjct: 87 SPQPCGPNSSCKNLSGRYKCSCLDGF 112
>AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domains
6 protein.
Length = 1229
Score = 180 bits (438), Expect = 2e-44
Identities = 213/832 (25%), Positives = 290/832 (34%), Gaps = 91/832 (10%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+DEC C+ C +TP + C C G+ S C ++ C+ G C+ CV
Sbjct: 57 VDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQ--HHCV 113
Query: 128 NLP-GAFECRCPPGYRLTPSLDECEDVDECGDQR-ICDHGDCRNTIGSYRCECKPGYTLR 185
L C+C PG++L C C ++ C H C+ G RCEC GY L
Sbjct: 114 QLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH-RCQVVRGLARCECHVGYQLA 172
Query: 186 EN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVD-----VNECR 237
+ C DVDEC+ C +G C N G++ C C G++ G + C VN C
Sbjct: 173 ADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCE 231
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTN 297
C +G C +T C C GY L D R C DVD+C + PC + CTN
Sbjct: 232 ANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCAD--SPCCQQ---VCTNNP 285
Query: 298 GGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAA 355
GGYEC C AG++L G C D DEC C C N G + C C AG+R +
Sbjct: 286 GGYECGCYAGYRLSADGCGCEDVDECASSRGGCE-HHCTNLAGSFQCSCEAGYRLHEDRR 344
Query: 356 VCVDERKELCYDEWE---AGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
C + + + E LQ P+ + +
Sbjct: 345 GCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKF 404
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCVGGRC-VNTDGSFRCECPDGYVLAPDGLSC---VD 468
+C + + D+CR GG C + DG C+CP+G+ +C
Sbjct: 405 VCLDDSFGHDCSLTCDDCR------NGGTCLLGLDG---CDCPEGWTGLICNETCPPDTF 455
Query: 469 ADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTF----R 523
C+ GTC + G C+C PG + + C R C R
Sbjct: 456 GKNCSFSCSCQNGGTCDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGR 513
Query: 524 CHNTAGSFRCT-------CPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKC 576
CH G+ C C A G C + +CVQ P +C+ GS C C
Sbjct: 514 CHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQ-PHT--QSCDKRDGS--CSC 568
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCI 636
G+R + E C + G C + G C AGF+ + G +C
Sbjct: 569 KAGFRGERCQAECELGYFGPG-CWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQEC- 626
Query: 637 DRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSE 696
GT C G +A C WG
Sbjct: 627 --PVGT-----FGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADC---PEGRWGLG 676
Query: 697 C-ELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP 755
C E+CPA AR D T L CA
Sbjct: 677 CQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRC-----SCAN-D 730
Query: 756 GLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 815
G C P C C PG+ G C + P C C+ + G C +G L E
Sbjct: 731 GHCHPATGHCSCAPGW--TGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEA 788
Query: 816 G-ANCRDVDECERDTH--TCQQICSNTEG------SYECSCEDGYEKRGDAC 858
G R +C + C+Q C G S C+C G+ RG C
Sbjct: 789 GYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGW--RGTFC 838
Score = 171 bits (415), Expect = 1e-41
Identities = 169/568 (29%), Positives = 227/568 (39%), Gaps = 83/568 (14%)
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG-DQRICDHGDC 167
DVDEC C+ +CVN PG++ C C PG+RL C ++ C C H
Sbjct: 56 DVDECRTHNGGCQH--RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCV 113
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVC-RNGT----CENLPGAYLCHCDDGF 222
+ TI +RC+C+PG+ L+E D C R P RNG+ C+ + G C C G+
Sbjct: 114 QLTITRHRCQCRPGFQLQE----DGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGY 169
Query: 223 K-AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDEL 281
+ A C DV+EC G C +G C NT GSF+C C GY L ADGR C ++ E+
Sbjct: 170 QLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEM--EI 226
Query: 282 PHPC-GRDGNPS--CTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGECRNF 336
+ C +G S C++T+ G C+C G++L R C+D D+C + P C C N
Sbjct: 227 VNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVCTNN 284
Query: 337 NGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAW- 395
GGY C C AG+R C D + C G C +C C G
Sbjct: 285 PGGYECGCYAGYRLSADGCGCED--VDECAS--SRGGCEHHCTNLAGSFQCSCEAGYRLH 340
Query: 396 --GRYCERCPAP-----DSAEFMR----ICQGGMGRPNLTQDLD------ECRVRPDVCV 438
R C P F+R I P L QD D E +R + +
Sbjct: 341 EDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTL 400
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSC---VDADEC--ALDPRICGNGTCSNTRGGYEC 493
+ V D SF +C +G +C +D +C IC N TC G C
Sbjct: 401 TEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLIC-NETCPPDTFGKNC 459
Query: 494 QCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCT--CPYGYAVAADGVHCRDI 551
S +C + C +C RC C CP GY G HCR
Sbjct: 460 SFS--------CSCQNGGTCDSVTGAC--RCPPGVSGTNCEDGCPKGYY----GKHCRKK 505
Query: 552 DECVQEPRVCPHACENVVGSYICKCPEGYRR----TSAPQDSENACEDINECEEQEDLCS 607
C R C + G+ +C P Y R T P C + +C +
Sbjct: 506 CNCANRGR-----CHRLYGACLCD-PGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQS- 558
Query: 608 GGVCINTDGSFLCDCDAGFEPSEDGTDC 635
C DGS C C AGF +C
Sbjct: 559 ---CDKRDGS--CSCKAGFRGERCQAEC 581
Score = 164 bits (398), Expect = 1e-39
Identities = 135/441 (30%), Positives = 177/441 (40%), Gaps = 62/441 (14%)
Query: 212 GAYLCHCDD-GFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G Y CH G+ + DV+ECR C++ RC NT GS+ CEC PG+ L D R
Sbjct: 35 GCYPCHLGQAGYPVSAGDQRPDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSR 93
Query: 271 NCRDVDECDELPHPCGRDG-NPSCTN-TNGGYECSCGAGWKLV--GRRCVDRDECKELPY 326
C ++ C G G C T + C C G++L GR CV R C
Sbjct: 94 TCLAINSC-----ALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNG 148
Query: 327 VCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAG--RCHRARPLQLAR 384
C C+ G CEC G++ C D DE AG +C
Sbjct: 149 SCMH-RCQVVRGLARCECHVGYQLAADGKACED------VDECAAGLAQCAHGCLNTQGS 201
Query: 385 PECCCSEG---AAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
+C C G A GR C R E + C+ G C G
Sbjct: 202 FKCVCHAGYELGADGRQCYRI----EMEIVNSCEANNGG----------------CSHG- 240
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
C +T C CP GY L D +C+D D+CA P C C+N GGYEC C G+
Sbjct: 241 CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYAGYRL 298
Query: 502 GPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQE--- 557
D C DVDECA R C C N AGSF+C+C GY + D C ++E + +
Sbjct: 299 SADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDG 358
Query: 558 --PRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTD 615
P V P V+ + P+ ++ D E A E + L VC+ D
Sbjct: 359 ELPFVRPLPHIAVLQD---ELPQLFQDDDVGADEEEA-----ELRGEHTLTEKFVCL--D 408
Query: 616 GSFLCDCDAGFEPSEDGTDCI 636
SF DC + +G C+
Sbjct: 409 DSFGHDCSLTCDDCRNGGTCL 429
Score = 158 bits (384), Expect = 7e-38
Identities = 183/655 (27%), Positives = 249/655 (38%), Gaps = 88/655 (13%)
Query: 49 LCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR 108
LC KPG ++ + I+ C + C+ T T +C C G++ C
Sbjct: 79 LCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCV 138
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRI-CDHGDC 167
C+ C M +C + G C C GY+L CEDVDEC C HG C
Sbjct: 139 RRSPCANRNGSC--MHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG-C 195
Query: 168 RNTIGSYRCECKPGYTLREN--VC-----RDVDECSRPRPVCRNGTCENLPGAYLCHCDD 220
NT GS++C C GY L + C V+ C C +G C + LC C
Sbjct: 196 LNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPR 254
Query: 221 GFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECD 279
G++ + C+DV++C + C C N G + C C GY L+ADG C DVDEC
Sbjct: 255 GYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECA 312
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRC-------VDRDE----CKELPY 326
C CTN G ++CSC AG++L R C VD D + LP+
Sbjct: 313 SSRGGC----EHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPH 368
Query: 327 VCAGGE--CRNFNGGYV--CECPAGWRFDKTAA---VCVDERKELCYD-EWEAGRCHRAR 378
+ + + F V E A R + T VC+D+ +D C
Sbjct: 369 IAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDD--SFGHDCSLTCDDCRNGG 426
Query: 379 PLQLARPECCCSEGAAW-GRYC-ERCPAPD----SAEFMRICQGGMGRPNLTQDLDECRV 432
L C C EG W G C E CP PD + F CQ G ++T CR
Sbjct: 427 TCLLGLDGCDCPEG--WTGLICNETCP-PDTFGKNCSFSCSCQNGGTCDSVT---GACRC 480
Query: 433 RPDVCVGGRCVNTDGSFRCECPDGYV--LAPDGLSCVDADECALDPRICGNGTCSNTRGG 490
P V G C DG CP GY +C + C R+ G C G
Sbjct: 481 PPGVS-GTNC--EDG-----CPKGYYGKHCRKKCNCANRGRC---HRLYGACLCDPGLYG 529
Query: 491 YECQCS-PGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR 549
C + P + GP C + +C + T C GS C+C G+ C
Sbjct: 530 RFCHLTCPPWAFGPG--CSEECQCVQPH---TQSCDKRDGS--CSCKAGFRGERCQAECE 582
Query: 550 --DIDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDL 605
+ CP AC++V G +CP G++ Q+ +N C
Sbjct: 583 LGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVN-CSSSCS- 640
Query: 606 CSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTG-----TCYRSLVSGRCEPE 655
C G C G C C G + DC + R G C + RC+PE
Sbjct: 641 CGGAPCHGVTGQ--CRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPE 693
Score = 157 bits (382), Expect = 1e-37
Identities = 84/214 (39%), Positives = 99/214 (46%), Gaps = 4/214 (1%)
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
D+DECR C RCVNT GS+ CEC G+ L D +C+ + CAL C +
Sbjct: 56 DVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 114
Query: 486 NTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
T + CQC PGF D + CV CA SC RC G RC C GY +AAD
Sbjct: 115 LTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAAD 174
Query: 545 GVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR-RTSAPQDSENACEDINECEEQE 603
G C D+DEC C H C N GS+ C C GY Q E +N CE
Sbjct: 175 GKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANN 234
Query: 604 DLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
CS G C +T LC C G+E D CID
Sbjct: 235 GGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCID 267
Score = 140 bits (339), Expect = 2e-32
Identities = 109/357 (30%), Positives = 152/357 (42%), Gaps = 48/357 (13%)
Query: 131 GAFECRC-PPGYRLTPSLDECEDVDECGDQRI-CDHGDCRNTIGSYRCECKPGYTLREN- 187
G + C GY ++ D+ DVDEC C H C NT GSY CECKPG+ L +
Sbjct: 35 GCYPCHLGQAGYPVSAG-DQRPDVDECRTHNGGCQHR-CVNTPGSYLCECKPGFRLHTDS 92
Query: 188 -VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRN 245
C ++ C+ C++ + + C C GF+ + CV + C C +
Sbjct: 93 RTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH 152
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
RC+ G RCEC GY L ADG+ C DVDEC C C NT G ++C C
Sbjct: 153 -RCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAH----GCLNTQGSFKCVCH 207
Query: 306 AGWKL--VGRRC--VDRD---ECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV 358
AG++L GR+C ++ + C+ C+ G C + + G +C CP G+ D C+
Sbjct: 208 AGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCI 266
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
D + C D + C + EC C G R+ G
Sbjct: 267 D--VDDCAD---SPCCQQVCTNNPGGYECGCYAG------------------YRLSADGC 303
Query: 419 GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
G +D+DEC C C N GSF+C C GY L D C +E +D
Sbjct: 304 G----CEDVDECASSRGGC-EHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVD 355
Score = 102 bits (245), Expect = 5e-21
Identities = 211/845 (24%), Positives = 280/845 (33%), Gaps = 128/845 (15%)
Query: 64 ETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGM 123
E + ++ C+ C G C T G C C GYE D C DVD+C+ P C+ +
Sbjct: 223 EMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCA-DSPCCQQV 280
Query: 124 AQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRI-CDHGDCRNTIGSYR--CEC-- 178
C N PG +EC C GYRL+ CEDVDEC R C+H C N GS++ CE
Sbjct: 281 --CTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEH-HCTNLAGSFQCSCEAGY 337
Query: 179 -----KPGYTLRENVCRDVD-ECSRPRPVCRNGTCEN-LPGAYLCHCDDGFKAGPNND-- 229
+ G + E D+D E RP+ ++ LP + DD A
Sbjct: 338 RLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQ---DDDVGADEEEAEL 394
Query: 230 -----------CVDVNECREGGMVCRNGRCRNT--VGSFRCECAPGYTLTADGRNCRDVD 276
C+D + + + C + R T +G C+C G+T C
Sbjct: 395 RGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDT 454
Query: 277 ECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNF 336
C +C + G C C G + G C D C + Y G CR
Sbjct: 455 FGKNCSFSCSCQNGGTCDSVTGA--CRCPPG--VSGTNC--EDGCPKGYY---GKHCRK- 504
Query: 337 NGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGR-CHRARPLQLARPECCCSEGAAW 395
C C R + C LC D GR CH P P C E
Sbjct: 505 ----KCNCANRGRCHRLYGAC------LC-DPGLYGRFCHLTCPPWAFGPGCS-EECQCV 552
Query: 396 GRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP---DVC---VGGRCVNTDGSF 449
+ + C D + C+ G + + P C VG C + G
Sbjct: 553 QPHTQSCDKRDGS---CSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGEC 609
Query: 450 RCECPDGYVLAPDGLSCVDAD---ECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT 506
CP G+ G C C+ CG C G +C+C PG T G D
Sbjct: 610 GKRCPAGFQGEDCGQECPVGTFGVNCSSSCS-CGGAPCHGVTG--QCRCPPGRT-GED-- 663
Query: 507 CVDVDECAEGR--ASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA 564
C + D C EGR C C + RC G + G + Q+ VCP
Sbjct: 664 C-EAD-CPEGRWGLGCQEICPACQHAARCDPETGACLCLPGF----VGSRCQD--VCPAG 715
Query: 565 CENVVGSYICKCP-EGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCD 623
C C +G+ P +C + C G D S C+C
Sbjct: 716 WYGPSCQTRCSCANDGHCH---PATGHCSCAPGWTGFSCQRACDTGHW-GPDCSHPCNCS 771
Query: 624 AGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKA 683
AG D I C V RCE + HV+ A
Sbjct: 772 AG----HGSCDAISGLC-LCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGA 826
Query: 684 QCCCTLGAAW-GSECE-LCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXX 741
CT A W G+ CE CPA LD +A N T
Sbjct: 827 ---CTCPAGWRGTFCEHACPA--GFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRC 881
Query: 742 LDVFADVDECAAIP--------GLCAPGRFRCVCGPGYRPAGEVCADV-------DECAV 786
+ D A GLC P RC+C G+ G+ C + CA
Sbjct: 882 AEKCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGW--TGDKCQSPCLRGWFGEACAQ 939
Query: 787 R-PPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC 845
R P CH+ G+ C C G+ G+ C R C+Q+C G C
Sbjct: 940 RCSCPPGAACHHVTGA--CRCPPGF----TGSGCEQGCPPGRYGPGCEQLCGCLNGG-SC 992
Query: 846 SCEDG 850
G
Sbjct: 993 DAATG 997
Score = 82.2 bits (194), Expect = 7e-15
Identities = 171/690 (24%), Positives = 235/690 (34%), Gaps = 108/690 (15%)
Query: 4 NEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPC-EACP-PRGSPAHTAL--CGEK-PGEYI 58
++ D SC+ G + C +G+ +G C +AC P G + CG++ P +
Sbjct: 560 DKRDGSCSCKAGFRGERCQAECELGY-FGPGCWQACTCPVGVACDSVSGECGKRCPAGFQ 618
Query: 59 NPVTNETKPIDECDI-MPQLCKPG--TCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECS 114
+ P+ + C G CH TG QC C G T C D E
Sbjct: 619 GEDCGQECPVGTFGVNCSSSCSCGGAPCHGV-TG-QCRCPPG----RTGEDCEADCPEGR 672
Query: 115 WGR------PPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV---DECGDQRIC-DH 164
WG P C+ A+C GA C C PG+ + D C C + C +
Sbjct: 673 WGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCAND 730
Query: 165 GDCRNTIGSYRCECKPGYT--LRENVCRDVD---ECSRP-RPVCRNGTCENLPGAYLCHC 218
G C G C C PG+T + C +CS P +G+C+ + G LC C
Sbjct: 731 GHCHPATG--HCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISG--LCLC 786
Query: 219 DDGFKAGPNNDCVDVNECREG--GMVCRNGRCRNTVG------SFRCECAPGYTLTADGR 270
+ G+ GP + +C +G G C RC+ G S C C G+ T
Sbjct: 787 EAGY-VGPRCE----QQCPQGHFGPGCEQ-RCQCQHGAACDHVSGACTCPAGWRGTFCEH 840
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDE---CKELPYV 327
C + C +C NG C G +C+ RD C+
Sbjct: 841 ACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGC 900
Query: 328 CAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPEC 387
GG C G C CPAGW DK + C+ W C + C
Sbjct: 901 LNGGLCDPHTGR--CLCPAGWTGDKCQSPCL--------RGWFGEACAQ---------RC 941
Query: 388 CCSEGAAWGRYCERCPAP---DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN 444
C GAA C P + + C G P Q L C GG C
Sbjct: 942 SCPPGAACHHVTGACRCPPGFTGSGCEQGCPPGRYGPGCEQ-LCGC------LNGGSCDA 994
Query: 445 TDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNG---TCSNTRGGYECQCSPGFTQ 501
G+ C CP G++ L+C +CG G C G C C PG
Sbjct: 995 ATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG--TCLCPPGRAG 1050
Query: 502 GPDQTCVDVDECAEG-RASCTFR----CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
+ + G +C+ R CH + GS C+C G+ G HC +
Sbjct: 1051 VRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGS--CSCGLGWT----GRHCELACPPGR 1104
Query: 557 EPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDG 616
C C + + C+ G R P ACE C G
Sbjct: 1105 YGAACHLEC-SCHNNSTCEPATGTCR-CGPGFYGQACEHRRSGATCNLDCRRGQ-FGPSC 1161
Query: 617 SFLCDCDAG--FEPSEDGTDCIDRRTG-TC 643
+ CDC G +P C+D G TC
Sbjct: 1162 TLHCDCGGGADCDPVSGQCHCVDGYMGPTC 1191
Score = 70.9 bits (166), Expect = 2e-11
Identities = 38/119 (31%), Positives = 49/119 (41%), Gaps = 9/119 (7%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLC-HN 797
DVDEC G C PG + C C PG+R C ++ CA+ C C
Sbjct: 56 DVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQL 115
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
T + C CR G++L EDG +C C +C C G C C GY+ D
Sbjct: 116 TITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAAD 174
Score = 66.1 bits (154), Expect = 5e-10
Identities = 160/630 (25%), Positives = 213/630 (33%), Gaps = 97/630 (15%)
Query: 70 ECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCR-DV--DECSWGRPPCRGMAQ 125
+C + C+ G TC G C C G+ + C D CS+ C+
Sbjct: 414 DCSLTCDDCRNGGTCLLGLDG--CDCPEGWTGLICNETCPPDTFGKNCSFSCS-CQNGGT 470
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECED---VDECGDQRIC-DHGDCRNTIGSYRCECKPG 181
C ++ GA CRCPPG T D C C + C + G C G+ C C PG
Sbjct: 471 CDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGA--CLCDPG 526
Query: 182 YTLR-----------ENVCRDVDECSRPR-PVC--RNGTCENLPG--AYLC--HCDDGFK 223
R C + +C +P C R+G+C G C C+ G+
Sbjct: 527 LYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGY- 585
Query: 224 AGPNNDCVDVNECREGGMVCR--NGRC-RNTVGSFRCE-CAPGYTLTADGRNCRDVDECD 279
GP C C G+ C +G C + F+ E C + G NC C
Sbjct: 586 FGPG--CWQACTC-PVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCG 642
Query: 280 ELPHPC-GRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVC--AGGECRNF 336
PC G G C G +C G C + + C G C
Sbjct: 643 GA--PCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCL 700
Query: 337 NG--GYVCE--CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEG 392
G G C+ CPAGW C C+ G C A + C G
Sbjct: 701 PGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHP--ATGHCSCAPGWTGFSCQRACDTG 758
Query: 393 AAWGRYCE---RCPAP----DSAEFMRICQGGMGRPNLTQDLDE------CRVRPDVCVG 439
WG C C A D+ + +C+ G P Q + C R G
Sbjct: 759 -HWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHG 817
Query: 440 GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT----CSNTRGGYECQC 495
C + G+ C CP G+ +C A LD R N T C G C C
Sbjct: 818 AACDHVSGA--CTCPAGWRGTFCEHAC-PAGFFGLDCRSACNCTAGAACDAVNG--SCLC 872
Query: 496 SPGFTQGPDQTCVDVDECAEGRASCTFR--CHN----TAGSFRCTCPYGYAVAADGVHCR 549
P +GP C + + RA C C N + RC CP G+ C
Sbjct: 873 -PAGRRGP--RCAEKCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCL 929
Query: 550 D--IDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDL 605
E + CP AC +V G+ C+CP G+ + Q CE+
Sbjct: 930 RGWFGEACAQRCSCPPGAACHHVTGA--CRCPPGFTGSGCEQGCPPGRYGPG-CEQLCGC 986
Query: 606 CSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
+GG C G+ C C GF GTDC
Sbjct: 987 LNGGSCDAATGA--CRCPTGFL----GTDC 1010
Score = 64.1 bits (149), Expect = 2e-09
Identities = 33/99 (33%), Positives = 43/99 (43%), Gaps = 3/99 (3%)
Query: 761 GRFRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
G + C G P AG+ DVDEC C C NT GSY C C+ G+ L D
Sbjct: 35 GCYPCHLGQAGYPVSAGDQRPDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRT 94
Query: 819 CRDVDECERDTHTCQQICSN-TEGSYECSCEDGYEKRGD 856
C ++ C CQ C T + C C G++ + D
Sbjct: 95 CLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQED 133
Score = 63.7 bits (148), Expect = 3e-09
Identities = 45/125 (36%), Positives = 55/125 (44%), Gaps = 14/125 (11%)
Query: 538 GYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDIN 597
GY V+A G D+DEC C H C N GSY+C+C G+R + DS C IN
Sbjct: 45 GYPVSA-GDQRPDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHT---DSRT-CLAIN 99
Query: 598 ECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDR-----RTGTCYR--SLVSG 650
C C T C C GF+ EDG C+ R R G+C +V G
Sbjct: 100 SCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRG 159
Query: 651 --RCE 653
RCE
Sbjct: 160 LARCE 164
Score = 47.2 bits (107), Expect = 2e-04
Identities = 24/59 (40%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 800 GSYDC-LCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA 857
G Y C L + GY + G DVDEC CQ C NT GSY C C+ G+ D+
Sbjct: 35 GCYPCHLGQAGYPVSA-GDQRPDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDS 92
>AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domains
6 protein.
Length = 1229
Score = 180 bits (438), Expect = 2e-44
Identities = 213/832 (25%), Positives = 290/832 (34%), Gaps = 91/832 (10%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
+DEC C+ C +TP + C C G+ S C ++ C+ G C+ CV
Sbjct: 57 VDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQ--HHCV 113
Query: 128 NLP-GAFECRCPPGYRLTPSLDECEDVDECGDQR-ICDHGDCRNTIGSYRCECKPGYTLR 185
L C+C PG++L C C ++ C H C+ G RCEC GY L
Sbjct: 114 QLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH-RCQVVRGLARCECHVGYQLA 172
Query: 186 EN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVD-----VNECR 237
+ C DVDEC+ C +G C N G++ C C G++ G + C VN C
Sbjct: 173 ADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCE 231
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTN 297
C +G C +T C C GY L D R C DVD+C + PC + CTN
Sbjct: 232 ANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCAD--SPCCQQ---VCTNNP 285
Query: 298 GGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAA 355
GGYEC C AG++L G C D DEC C C N G + C C AG+R +
Sbjct: 286 GGYECGCYAGYRLSADGCGCEDVDECASSRGGCE-HHCTNLAGSFQCSCEAGYRLHEDRR 344
Query: 356 VCVDERKELCYDEWE---AGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMR 412
C + + + E LQ P+ + +
Sbjct: 345 GCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKF 404
Query: 413 ICQGGMGRPNLTQDLDECRVRPDVCVGGRC-VNTDGSFRCECPDGYVLAPDGLSC---VD 468
+C + + D+CR GG C + DG C+CP+G+ +C
Sbjct: 405 VCLDDSFGHDCSLTCDDCR------NGGTCLLGLDG---CDCPEGWTGLICNETCPPDTF 455
Query: 469 ADECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTF----R 523
C+ GTC + G C+C PG + + C R C R
Sbjct: 456 GKNCSFSCSCQNGGTCDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGR 513
Query: 524 CHNTAGSFRCT-------CPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKC 576
CH G+ C C A G C + +CVQ P +C+ GS C C
Sbjct: 514 CHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQ-PHT--QSCDKRDGS--CSC 568
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCI 636
G+R + E C + G C + G C AGF+ + G +C
Sbjct: 569 KAGFRGERCQAECELGYFGPG-CWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQEC- 626
Query: 637 DRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAAWGSE 696
GT C G +A C WG
Sbjct: 627 --PVGT-----FGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADC---PEGRWGLG 676
Query: 697 C-ELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECAAIP 755
C E+CPA AR D T L CA
Sbjct: 677 CQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRC-----SCAN-D 730
Query: 756 GLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 815
G C P C C PG+ G C + P C C+ + G C +G L E
Sbjct: 731 GHCHPATGHCSCAPGW--TGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEA 788
Query: 816 G-ANCRDVDECERDTH--TCQQICSNTEG------SYECSCEDGYEKRGDAC 858
G R +C + C+Q C G S C+C G+ RG C
Sbjct: 789 GYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGW--RGTFC 838
Score = 171 bits (415), Expect = 1e-41
Identities = 169/568 (29%), Positives = 227/568 (39%), Gaps = 83/568 (14%)
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG-DQRICDHGDC 167
DVDEC C+ +CVN PG++ C C PG+RL C ++ C C H
Sbjct: 56 DVDECRTHNGGCQH--RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCV 113
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVC-RNGT----CENLPGAYLCHCDDGF 222
+ TI +RC+C+PG+ L+E D C R P RNG+ C+ + G C C G+
Sbjct: 114 QLTITRHRCQCRPGFQLQE----DGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGY 169
Query: 223 K-AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDEL 281
+ A C DV+EC G C +G C NT GSF+C C GY L ADGR C ++ E+
Sbjct: 170 QLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEM--EI 226
Query: 282 PHPC-GRDGNPS--CTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGECRNF 336
+ C +G S C++T+ G C+C G++L R C+D D+C + P C C N
Sbjct: 227 VNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVCTNN 284
Query: 337 NGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAW- 395
GGY C C AG+R C D + C G C +C C G
Sbjct: 285 PGGYECGCYAGYRLSADGCGCED--VDECAS--SRGGCEHHCTNLAGSFQCSCEAGYRLH 340
Query: 396 --GRYCERCPAP-----DSAEFMR----ICQGGMGRPNLTQDLD------ECRVRPDVCV 438
R C P F+R I P L QD D E +R + +
Sbjct: 341 EDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTL 400
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSC---VDADEC--ALDPRICGNGTCSNTRGGYEC 493
+ V D SF +C +G +C +D +C IC N TC G C
Sbjct: 401 TEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLIC-NETCPPDTFGKNC 459
Query: 494 QCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCT--CPYGYAVAADGVHCRDI 551
S +C + C +C RC C CP GY G HCR
Sbjct: 460 SFS--------CSCQNGGTCDSVTGAC--RCPPGVSGTNCEDGCPKGYY----GKHCRKK 505
Query: 552 DECVQEPRVCPHACENVVGSYICKCPEGYRR----TSAPQDSENACEDINECEEQEDLCS 607
C R C + G+ +C P Y R T P C + +C +
Sbjct: 506 CNCANRGR-----CHRLYGACLCD-PGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQS- 558
Query: 608 GGVCINTDGSFLCDCDAGFEPSEDGTDC 635
C DGS C C AGF +C
Sbjct: 559 ---CDKRDGS--CSCKAGFRGERCQAEC 581
Score = 164 bits (398), Expect = 1e-39
Identities = 135/441 (30%), Positives = 177/441 (40%), Gaps = 62/441 (14%)
Query: 212 GAYLCHCDD-GFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G Y CH G+ + DV+ECR C++ RC NT GS+ CEC PG+ L D R
Sbjct: 35 GCYPCHLGQAGYPVSAGDQRPDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSR 93
Query: 271 NCRDVDECDELPHPCGRDG-NPSCTN-TNGGYECSCGAGWKLV--GRRCVDRDECKELPY 326
C ++ C G G C T + C C G++L GR CV R C
Sbjct: 94 TCLAINSC-----ALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNG 148
Query: 327 VCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAG--RCHRARPLQLAR 384
C C+ G CEC G++ C D DE AG +C
Sbjct: 149 SCMH-RCQVVRGLARCECHVGYQLAADGKACED------VDECAAGLAQCAHGCLNTQGS 201
Query: 385 PECCCSEG---AAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
+C C G A GR C R E + C+ G C G
Sbjct: 202 FKCVCHAGYELGADGRQCYRI----EMEIVNSCEANNGG----------------CSHG- 240
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
C +T C CP GY L D +C+D D+CA P C C+N GGYEC C G+
Sbjct: 241 CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYAGYRL 298
Query: 502 GPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQE--- 557
D C DVDECA R C C N AGSF+C+C GY + D C ++E + +
Sbjct: 299 SADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDG 358
Query: 558 --PRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTD 615
P V P V+ + P+ ++ D E A E + L VC+ D
Sbjct: 359 ELPFVRPLPHIAVLQD---ELPQLFQDDDVGADEEEA-----ELRGEHTLTEKFVCL--D 408
Query: 616 GSFLCDCDAGFEPSEDGTDCI 636
SF DC + +G C+
Sbjct: 409 DSFGHDCSLTCDDCRNGGTCL 429
Score = 158 bits (384), Expect = 7e-38
Identities = 183/655 (27%), Positives = 249/655 (38%), Gaps = 88/655 (13%)
Query: 49 LCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCR 108
LC KPG ++ + I+ C + C+ T T +C C G++ C
Sbjct: 79 LCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCV 138
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRI-CDHGDC 167
C+ C M +C + G C C GY+L CEDVDEC C HG C
Sbjct: 139 RRSPCANRNGSC--MHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG-C 195
Query: 168 RNTIGSYRCECKPGYTLREN--VC-----RDVDECSRPRPVCRNGTCENLPGAYLCHCDD 220
NT GS++C C GY L + C V+ C C +G C + LC C
Sbjct: 196 LNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPR 254
Query: 221 GFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECD 279
G++ + C+DV++C + C C N G + C C GY L+ADG C DVDEC
Sbjct: 255 GYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECA 312
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRC-------VDRDE----CKELPY 326
C CTN G ++CSC AG++L R C VD D + LP+
Sbjct: 313 SSRGGC----EHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPH 368
Query: 327 VCAGGE--CRNFNGGYV--CECPAGWRFDKTAA---VCVDERKELCYD-EWEAGRCHRAR 378
+ + + F V E A R + T VC+D+ +D C
Sbjct: 369 IAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDD--SFGHDCSLTCDDCRNGG 426
Query: 379 PLQLARPECCCSEGAAW-GRYC-ERCPAPD----SAEFMRICQGGMGRPNLTQDLDECRV 432
L C C EG W G C E CP PD + F CQ G ++T CR
Sbjct: 427 TCLLGLDGCDCPEG--WTGLICNETCP-PDTFGKNCSFSCSCQNGGTCDSVT---GACRC 480
Query: 433 RPDVCVGGRCVNTDGSFRCECPDGYV--LAPDGLSCVDADECALDPRICGNGTCSNTRGG 490
P V G C DG CP GY +C + C R+ G C G
Sbjct: 481 PPGVS-GTNC--EDG-----CPKGYYGKHCRKKCNCANRGRC---HRLYGACLCDPGLYG 529
Query: 491 YECQCS-PGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR 549
C + P + GP C + +C + T C GS C+C G+ C
Sbjct: 530 RFCHLTCPPWAFGPG--CSEECQCVQPH---TQSCDKRDGS--CSCKAGFRGERCQAECE 582
Query: 550 --DIDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDL 605
+ CP AC++V G +CP G++ Q+ +N C
Sbjct: 583 LGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVN-CSSSCS- 640
Query: 606 CSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTG-----TCYRSLVSGRCEPE 655
C G C G C C G + DC + R G C + RC+PE
Sbjct: 641 CGGAPCHGVTGQ--CRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPE 693
Score = 157 bits (382), Expect = 1e-37
Identities = 84/214 (39%), Positives = 99/214 (46%), Gaps = 4/214 (1%)
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
D+DECR C RCVNT GS+ CEC G+ L D +C+ + CAL C +
Sbjct: 56 DVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 114
Query: 486 NTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
T + CQC PGF D + CV CA SC RC G RC C GY +AAD
Sbjct: 115 LTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAAD 174
Query: 545 GVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR-RTSAPQDSENACEDINECEEQE 603
G C D+DEC C H C N GS+ C C GY Q E +N CE
Sbjct: 175 GKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANN 234
Query: 604 DLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
CS G C +T LC C G+E D CID
Sbjct: 235 GGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCID 267
Score = 140 bits (339), Expect = 2e-32
Identities = 109/357 (30%), Positives = 152/357 (42%), Gaps = 48/357 (13%)
Query: 131 GAFECRC-PPGYRLTPSLDECEDVDECGDQRI-CDHGDCRNTIGSYRCECKPGYTLREN- 187
G + C GY ++ D+ DVDEC C H C NT GSY CECKPG+ L +
Sbjct: 35 GCYPCHLGQAGYPVSAG-DQRPDVDECRTHNGGCQHR-CVNTPGSYLCECKPGFRLHTDS 92
Query: 188 -VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRN 245
C ++ C+ C++ + + C C GF+ + CV + C C +
Sbjct: 93 RTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH 152
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
RC+ G RCEC GY L ADG+ C DVDEC C C NT G ++C C
Sbjct: 153 -RCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAH----GCLNTQGSFKCVCH 207
Query: 306 AGWKL--VGRRC--VDRD---ECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV 358
AG++L GR+C ++ + C+ C+ G C + + G +C CP G+ D C+
Sbjct: 208 AGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCI 266
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
D + C D + C + EC C G R+ G
Sbjct: 267 D--VDDCAD---SPCCQQVCTNNPGGYECGCYAG------------------YRLSADGC 303
Query: 419 GRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
G +D+DEC C C N GSF+C C GY L D C +E +D
Sbjct: 304 G----CEDVDECASSRGGC-EHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVD 355
Score = 102 bits (245), Expect = 5e-21
Identities = 211/845 (24%), Positives = 280/845 (33%), Gaps = 128/845 (15%)
Query: 64 ETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGM 123
E + ++ C+ C G C T G C C GYE D C DVD+C+ P C+ +
Sbjct: 223 EMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCA-DSPCCQQV 280
Query: 124 AQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRI-CDHGDCRNTIGSYR--CEC-- 178
C N PG +EC C GYRL+ CEDVDEC R C+H C N GS++ CE
Sbjct: 281 --CTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEH-HCTNLAGSFQCSCEAGY 337
Query: 179 -----KPGYTLRENVCRDVD-ECSRPRPVCRNGTCEN-LPGAYLCHCDDGFKAGPNND-- 229
+ G + E D+D E RP+ ++ LP + DD A
Sbjct: 338 RLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQ---DDDVGADEEEAEL 394
Query: 230 -----------CVDVNECREGGMVCRNGRCRNT--VGSFRCECAPGYTLTADGRNCRDVD 276
C+D + + + C + R T +G C+C G+T C
Sbjct: 395 RGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDT 454
Query: 277 ECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNF 336
C +C + G C C G + G C D C + Y G CR
Sbjct: 455 FGKNCSFSCSCQNGGTCDSVTGA--CRCPPG--VSGTNC--EDGCPKGYY---GKHCRK- 504
Query: 337 NGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGR-CHRARPLQLARPECCCSEGAAW 395
C C R + C LC D GR CH P P C E
Sbjct: 505 ----KCNCANRGRCHRLYGAC------LC-DPGLYGRFCHLTCPPWAFGPGCS-EECQCV 552
Query: 396 GRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP---DVC---VGGRCVNTDGSF 449
+ + C D + C+ G + + P C VG C + G
Sbjct: 553 QPHTQSCDKRDGS---CSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGEC 609
Query: 450 RCECPDGYVLAPDGLSCVDAD---ECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT 506
CP G+ G C C+ CG C G +C+C PG T G D
Sbjct: 610 GKRCPAGFQGEDCGQECPVGTFGVNCSSSCS-CGGAPCHGVTG--QCRCPPGRT-GED-- 663
Query: 507 CVDVDECAEGR--ASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA 564
C + D C EGR C C + RC G + G + Q+ VCP
Sbjct: 664 C-EAD-CPEGRWGLGCQEICPACQHAARCDPETGACLCLPGF----VGSRCQD--VCPAG 715
Query: 565 CENVVGSYICKCP-EGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCD 623
C C +G+ P +C + C G D S C+C
Sbjct: 716 WYGPSCQTRCSCANDGHCH---PATGHCSCAPGWTGFSCQRACDTGHW-GPDCSHPCNCS 771
Query: 624 AGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKA 683
AG D I C V RCE + HV+ A
Sbjct: 772 AG----HGSCDAISGLC-LCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGA 826
Query: 684 QCCCTLGAAW-GSECE-LCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXX 741
CT A W G+ CE CPA LD +A N T
Sbjct: 827 ---CTCPAGWRGTFCEHACPA--GFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRC 881
Query: 742 LDVFADVDECAAIP--------GLCAPGRFRCVCGPGYRPAGEVCADV-------DECAV 786
+ D A GLC P RC+C G+ G+ C + CA
Sbjct: 882 AEKCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGW--TGDKCQSPCLRGWFGEACAQ 939
Query: 787 R-PPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC 845
R P CH+ G+ C C G+ G+ C R C+Q+C G C
Sbjct: 940 RCSCPPGAACHHVTGA--CRCPPGF----TGSGCEQGCPPGRYGPGCEQLCGCLNGG-SC 992
Query: 846 SCEDG 850
G
Sbjct: 993 DAATG 997
Score = 82.2 bits (194), Expect = 7e-15
Identities = 171/690 (24%), Positives = 235/690 (34%), Gaps = 108/690 (15%)
Query: 4 NEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPC-EACP-PRGSPAHTAL--CGEK-PGEYI 58
++ D SC+ G + C +G+ +G C +AC P G + CG++ P +
Sbjct: 560 DKRDGSCSCKAGFRGERCQAECELGY-FGPGCWQACTCPVGVACDSVSGECGKRCPAGFQ 618
Query: 59 NPVTNETKPIDECDI-MPQLCKPG--TCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECS 114
+ P+ + C G CH TG QC C G T C D E
Sbjct: 619 GEDCGQECPVGTFGVNCSSSCSCGGAPCHGV-TG-QCRCPPG----RTGEDCEADCPEGR 672
Query: 115 WGR------PPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV---DECGDQRIC-DH 164
WG P C+ A+C GA C C PG+ + D C C + C +
Sbjct: 673 WGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCAND 730
Query: 165 GDCRNTIGSYRCECKPGYT--LRENVCRDVD---ECSRP-RPVCRNGTCENLPGAYLCHC 218
G C G C C PG+T + C +CS P +G+C+ + G LC C
Sbjct: 731 GHCHPATG--HCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISG--LCLC 786
Query: 219 DDGFKAGPNNDCVDVNECREG--GMVCRNGRCRNTVG------SFRCECAPGYTLTADGR 270
+ G+ GP + +C +G G C RC+ G S C C G+ T
Sbjct: 787 EAGY-VGPRCE----QQCPQGHFGPGCEQ-RCQCQHGAACDHVSGACTCPAGWRGTFCEH 840
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDE---CKELPYV 327
C + C +C NG C G +C+ RD C+
Sbjct: 841 ACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGC 900
Query: 328 CAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPEC 387
GG C G C CPAGW DK + C+ W C + C
Sbjct: 901 LNGGLCDPHTGR--CLCPAGWTGDKCQSPCL--------RGWFGEACAQ---------RC 941
Query: 388 CCSEGAAWGRYCERCPAP---DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN 444
C GAA C P + + C G P Q L C GG C
Sbjct: 942 SCPPGAACHHVTGACRCPPGFTGSGCEQGCPPGRYGPGCEQ-LCGC------LNGGSCDA 994
Query: 445 TDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNG---TCSNTRGGYECQCSPGFTQ 501
G+ C CP G++ L+C +CG G C G C C PG
Sbjct: 995 ATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG--TCLCPPGRAG 1050
Query: 502 GPDQTCVDVDECAEG-RASCTFR----CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
+ + G +C+ R CH + GS C+C G+ G HC +
Sbjct: 1051 VRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGS--CSCGLGWT----GRHCELACPPGR 1104
Query: 557 EPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDG 616
C C + + C+ G R P ACE C G
Sbjct: 1105 YGAACHLEC-SCHNNSTCEPATGTCR-CGPGFYGQACEHRRSGATCNLDCRRGQ-FGPSC 1161
Query: 617 SFLCDCDAG--FEPSEDGTDCIDRRTG-TC 643
+ CDC G +P C+D G TC
Sbjct: 1162 TLHCDCGGGADCDPVSGQCHCVDGYMGPTC 1191
Score = 70.9 bits (166), Expect = 2e-11
Identities = 38/119 (31%), Positives = 49/119 (41%), Gaps = 9/119 (7%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLC-HN 797
DVDEC G C PG + C C PG+R C ++ CA+ C C
Sbjct: 56 DVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQL 115
Query: 798 TDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
T + C CR G++L EDG +C C +C C G C C GY+ D
Sbjct: 116 TITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAAD 174
Score = 66.1 bits (154), Expect = 5e-10
Identities = 160/630 (25%), Positives = 213/630 (33%), Gaps = 97/630 (15%)
Query: 70 ECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCR-DV--DECSWGRPPCRGMAQ 125
+C + C+ G TC G C C G+ + C D CS+ C+
Sbjct: 414 DCSLTCDDCRNGGTCLLGLDG--CDCPEGWTGLICNETCPPDTFGKNCSFSCS-CQNGGT 470
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECED---VDECGDQRIC-DHGDCRNTIGSYRCECKPG 181
C ++ GA CRCPPG T D C C + C + G C G+ C C PG
Sbjct: 471 CDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGA--CLCDPG 526
Query: 182 YTLR-----------ENVCRDVDECSRPR-PVC--RNGTCENLPG--AYLC--HCDDGFK 223
R C + +C +P C R+G+C G C C+ G+
Sbjct: 527 LYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGY- 585
Query: 224 AGPNNDCVDVNECREGGMVCR--NGRC-RNTVGSFRCE-CAPGYTLTADGRNCRDVDECD 279
GP C C G+ C +G C + F+ E C + G NC C
Sbjct: 586 FGPG--CWQACTC-PVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCG 642
Query: 280 ELPHPC-GRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVC--AGGECRNF 336
PC G G C G +C G C + + C G C
Sbjct: 643 GA--PCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCL 700
Query: 337 NG--GYVCE--CPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEG 392
G G C+ CPAGW C C+ G C A + C G
Sbjct: 701 PGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHP--ATGHCSCAPGWTGFSCQRACDTG 758
Query: 393 AAWGRYCE---RCPAP----DSAEFMRICQGGMGRPNLTQDLDE------CRVRPDVCVG 439
WG C C A D+ + +C+ G P Q + C R G
Sbjct: 759 -HWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHG 817
Query: 440 GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT----CSNTRGGYECQC 495
C + G+ C CP G+ +C A LD R N T C G C C
Sbjct: 818 AACDHVSGA--CTCPAGWRGTFCEHAC-PAGFFGLDCRSACNCTAGAACDAVNG--SCLC 872
Query: 496 SPGFTQGPDQTCVDVDECAEGRASCTFR--CHN----TAGSFRCTCPYGYAVAADGVHCR 549
P +GP C + + RA C C N + RC CP G+ C
Sbjct: 873 -PAGRRGP--RCAEKCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCL 929
Query: 550 D--IDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDL 605
E + CP AC +V G+ C+CP G+ + Q CE+
Sbjct: 930 RGWFGEACAQRCSCPPGAACHHVTGA--CRCPPGFTGSGCEQGCPPGRYGPG-CEQLCGC 986
Query: 606 CSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
+GG C G+ C C GF GTDC
Sbjct: 987 LNGGSCDAATGA--CRCPTGFL----GTDC 1010
Score = 64.1 bits (149), Expect = 2e-09
Identities = 33/99 (33%), Positives = 43/99 (43%), Gaps = 3/99 (3%)
Query: 761 GRFRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
G + C G P AG+ DVDEC C C NT GSY C C+ G+ L D
Sbjct: 35 GCYPCHLGQAGYPVSAGDQRPDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRT 94
Query: 819 CRDVDECERDTHTCQQICSN-TEGSYECSCEDGYEKRGD 856
C ++ C CQ C T + C C G++ + D
Sbjct: 95 CLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQED 133
Score = 63.7 bits (148), Expect = 3e-09
Identities = 45/125 (36%), Positives = 55/125 (44%), Gaps = 14/125 (11%)
Query: 538 GYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDIN 597
GY V+A G D+DEC C H C N GSY+C+C G+R + DS C IN
Sbjct: 45 GYPVSA-GDQRPDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHT---DSRT-CLAIN 99
Query: 598 ECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDR-----RTGTCYR--SLVSG 650
C C T C C GF+ EDG C+ R R G+C +V G
Sbjct: 100 SCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRG 159
Query: 651 --RCE 653
RCE
Sbjct: 160 LARCE 164
Score = 47.2 bits (107), Expect = 2e-04
Identities = 24/59 (40%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 800 GSYDC-LCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA 857
G Y C L + GY + G DVDEC CQ C NT GSY C C+ G+ D+
Sbjct: 35 GCYPCHLGQAGYPVSA-GDQRPDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDS 92
>AB065918-1|BAC06133.1| 929|Homo sapiens seven transmembrane helix
receptor protein.
Length = 929
Score = 180 bits (438), Expect = 2e-44
Identities = 95/259 (36%), Positives = 126/259 (48%), Gaps = 36/259 (13%)
Query: 82 TCHDTPTGFQCGCDHGYEHDN-TSHL------CRDVDECSWGRPPCRGMAQCVNLPGAFE 134
TC +T + C C G+ N +H C+D+DECS PC + C NL G ++
Sbjct: 64 TCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYK 123
Query: 135 CRCPPGYRLTPSLD---------ECEDVDECGDQRIC-DHGDCRNTIGSYRCECKPGYTL 184
C C G+ D C D++EC +C +H DC N++GSY C C+ G+
Sbjct: 124 CSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFIS 183
Query: 185 RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA--------GPNNDCVDVNEC 236
R + C DVDEC+ PR + TC N G Y C C+ GF++ G C D++EC
Sbjct: 184 RNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDEC 243
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGY-------TLTADGRNCRDVDECDELPHPCGRDG 289
E M N C NT GS+ C C PG+ T G CRD+DEC + P CG
Sbjct: 244 TE--MCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCG--P 299
Query: 290 NPSCTNTNGGYECSCGAGW 308
N CTN G Y C C AG+
Sbjct: 300 NSICTNALGSYSCGCIAGF 318
Score = 141 bits (341), Expect = 1e-32
Identities = 84/255 (32%), Positives = 113/255 (44%), Gaps = 34/255 (13%)
Query: 66 KPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHL---------CRDVDECSW 115
K IDEC PQ C P + C + ++C C G+ + C D++EC
Sbjct: 97 KDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLT 156
Query: 116 GRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRIC-DHGDCRNTIGSY 174
C + CVN G++ C C G+ S CEDVDEC D R C +H C NT+G+Y
Sbjct: 157 SSV-CPEHSDCVNSMGSYSCSCQVGFISRNST--CEDVDECADPRACPEHATCNNTVGNY 213
Query: 175 RCECKPGYTLREN---------VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA- 224
C C PG+ C D+DEC+ P+ N TC N PG+Y C C GF
Sbjct: 214 SCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGFAPS 271
Query: 225 -GPNN------DCVDVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTLTADGRNCRDVD 276
G N +C D++ECR+ C N C N +GS+ C C G+ +G
Sbjct: 272 NGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNF 331
Query: 277 ECDELPHPCGRDGNP 291
C + C D P
Sbjct: 332 SCQRVLFKCKEDVIP 346
Score = 140 bits (339), Expect = 2e-32
Identities = 80/234 (34%), Positives = 110/234 (47%), Gaps = 30/234 (12%)
Query: 425 QDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLA---------PDGLSCVDADECAL 474
+D+DEC P C C N G ++C C DG+ P SC D +EC L
Sbjct: 97 KDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-L 155
Query: 475 DPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFR 532
+C + C N+ G Y C C GF + TC DVDECA+ RA C+NT G++
Sbjct: 156 TSSVCPEHSDCVNSMGSYSCSCQVGFI-SRNSTCEDVDECADPRACPEHATCNNTVGNYS 214
Query: 533 CTCPYGYAVAADGV-------HCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRT 583
C C G+ ++ + C DIDEC + +CP C N GSY C C G+ +
Sbjct: 215 CFCNPGFESSSGHLSFQGLKASCEDIDECTE---MCPINSTCTNTPGSYFCTCHPGFAPS 271
Query: 584 SAP---QDSENACEDINECEEQEDLCS-GGVCINTDGSFLCDCDAGFEPSEDGT 633
+ D C DI+EC + C +C N GS+ C C AGF P+ +G+
Sbjct: 272 NGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGS 325
Score = 135 bits (327), Expect = 5e-31
Identities = 79/221 (35%), Positives = 111/221 (50%), Gaps = 29/221 (13%)
Query: 442 CVNTDGSFRCECPDGYVLA-------PDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
C NT S+ C C G++ + G+ C D DEC+ P+ CG N +C N G Y+C
Sbjct: 65 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKC 124
Query: 494 QCSPGFTQ--GPDQ--------TCVDVDECAEGRASCTFR-CHNTAGSFRCTCPYGYAVA 542
C GF+ G D +C D++EC C N+ GS+ C+C G+ ++
Sbjct: 125 SCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGF-IS 183
Query: 543 ADGVHCRDIDECVQEPRVCP-HA-CENVVGSYICKCPEGYRRTSAP---QDSENACEDIN 597
+ C D+DEC +PR CP HA C N VG+Y C C G+ +S Q + +CEDI+
Sbjct: 184 RNST-CEDVDECA-DPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDID 241
Query: 598 ECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDR 638
EC E + S C NT GS+ C C GF PS + D+
Sbjct: 242 ECTEMCPINS--TCTNTPGSYFCTCHPGFAPSNGQLNFTDQ 280
Score = 128 bits (309), Expect = 8e-29
Identities = 101/307 (32%), Positives = 138/307 (44%), Gaps = 39/307 (12%)
Query: 319 DECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRAR 378
+ C++ A C N Y C C G+ D C D E C ++
Sbjct: 51 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR-CKDIDE---CSQSP 106
Query: 379 PLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRP-NLT-QDLDECRVRPDV 436
Q P C + GRY +C D G+P N + D++EC + V
Sbjct: 107 --QPCGPNSSCKNLS--GRY--KCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-LTSSV 159
Query: 437 CVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQ 494
C CVN+ GS+ C C G++ +C D DECA DPR C + TC+NT G Y C
Sbjct: 160 CPEHSDCVNSMGSYSCSCQVGFISRNS--TCEDVDECA-DPRACPEHATCNNTVGNYSCF 216
Query: 495 CSPGFT--------QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA------ 540
C+PGF QG +C D+DEC E C NT GS+ CTC G+A
Sbjct: 217 CNPGFESSSGHLSFQGLKASCEDIDECTE-MCPINSTCTNTPGSYFCTCHPGFAPSNGQL 275
Query: 541 -VAADGVHCRDIDECVQEPRVC-PHA-CENVVGSYICKCPEGYRRT--SAPQDSENACED 595
GV CRDIDEC Q+P C P++ C N +GSY C C G+ + +D +C+
Sbjct: 276 NFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQR 335
Query: 596 I-NECEE 601
+ +C+E
Sbjct: 336 VLFKCKE 342
Score = 126 bits (305), Expect = 3e-28
Identities = 82/266 (30%), Positives = 115/266 (43%), Gaps = 43/266 (16%)
Query: 120 CRGMAQCVNLPGAFECRCPPGYRLTPSLD-------ECEDVDECGD--QRICDHGDCRNT 170
C A C N ++ C C G+ + + C+D+DEC Q + C+N
Sbjct: 59 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNL 118
Query: 171 IGSYRCECKPGYTLREN-----------VCRDVDECSRPRPVCRNGTCENLPGAYLCHCD 219
G Y+C C G++ C D++EC + C N G+Y C C
Sbjct: 119 SGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQ 178
Query: 220 DGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYT-----LTADG--RNC 272
GF N+ C DV+EC + + C NTVG++ C C PG+ L+ G +C
Sbjct: 179 VGF-ISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASC 237
Query: 273 RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL---------VGRRCVDRDECKE 323
D+DEC E+ C N +CTNT G Y C+C G+ G C D DEC++
Sbjct: 238 EDIDECTEM---C--PINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQ 292
Query: 324 LPYVCAGGE-CRNFNGGYVCECPAGW 348
P C C N G Y C C AG+
Sbjct: 293 DPSTCGPNSICTNALGSYSCGCIAGF 318
Score = 99.1 bits (236), Expect = 6e-20
Identities = 89/328 (27%), Positives = 124/328 (37%), Gaps = 48/328 (14%)
Query: 159 QRICDHGDC---RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYL 215
Q++ G C + G R KP + N CRD C TC N +Y
Sbjct: 22 QKLAGRGGCCVMHSWEGHIRPTRKPN--TKGNNCRDSTLCPA------YATCTNTVDSYY 73
Query: 216 CHCDDGFKAG--------PNNDCVDVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTLT 266
C C GF + P C D++EC + C N C+N G ++C C G++
Sbjct: 74 CACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSP 133
Query: 267 AD-----GR----NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVD 317
G+ +C D++EC C + C N+ G Y CSC G+ C D
Sbjct: 134 TGNDWVPGKPGNFSCTDINEC-LTSSVCPEHSD--CVNSMGSYSCSCQVGFISRNSTCED 190
Query: 318 RDECKELPYVC-AGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHR 376
DEC + P C C N G Y C C G+ + + K C D C
Sbjct: 191 VDECAD-PRACPEHATCNNTVGNYSCFCNPGFE-SSSGHLSFQGLKASCED---IDECTE 245
Query: 377 ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDV 436
P+ C + ++ C AP + + QG R D+DECR P
Sbjct: 246 MCPIN----STCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECR-----DIDECRQDPST 296
Query: 437 C-VGGRCVNTDGSFRCECPDGYVLAPDG 463
C C N GS+ C C G+ P+G
Sbjct: 297 CGPNSICTNALGSYSCGCIAGFHPNPEG 324
Score = 92.7 bits (220), Expect = 5e-18
Identities = 58/177 (32%), Positives = 82/177 (46%), Gaps = 29/177 (16%)
Query: 475 DPRIC-GNGTCSNTRGGYECQCSPGFTQG--------PDQTCVDVDECAEGRASC--TFR 523
D +C TC+NT Y C C GF P C D+DEC++ C
Sbjct: 55 DSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSS 114
Query: 524 CHNTAGSFRCTCPYGYA--VAADGV-------HCRDIDECVQEPRVCP-HA-CENVVGSY 572
C N +G ++C+C G++ D V C DI+EC+ VCP H+ C N +GSY
Sbjct: 115 CKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS-VCPEHSDCVNSMGSY 173
Query: 573 ICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPS 629
C C G+ ++ CED++EC + C NT G++ C C+ GFE S
Sbjct: 174 SCSCQVGFISRNS------TCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESS 224
Score = 81.8 bits (193), Expect = 9e-15
Identities = 49/130 (37%), Positives = 61/130 (46%), Gaps = 26/130 (20%)
Query: 747 DVDECA---AIP--GLC--APGRFRCVCGPGYRPA-GEV--------CADVDECAVRPPP 790
DVDECA A P C G + C C PG+ + G + C D+DEC P
Sbjct: 190 DVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT-EMCP 248
Query: 791 CDQLCHNTDGSYDCLCRTGY-------ELDEDGANCRDVDECERDTHTC--QQICSNTEG 841
+ C NT GSY C C G+ + G CRD+DEC +D TC IC+N G
Sbjct: 249 INSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALG 308
Query: 842 SYECSCEDGY 851
SY C C G+
Sbjct: 309 SYSCGCIAGF 318
Score = 76.2 bits (179), Expect = 5e-13
Identities = 41/101 (40%), Positives = 51/101 (50%), Gaps = 13/101 (12%)
Query: 761 GRFRCVCGPGYRPAGEVCADVDECA-VRPPPCDQLCHNTDGSYDCLCRTGYE-----LDE 814
G + C C G+ C DVDECA R P C+NT G+Y C C G+E L
Sbjct: 171 GSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSF 230
Query: 815 DG--ANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGY 851
G A+C D+DEC T C C+NT GSY C+C G+
Sbjct: 231 QGLKASCEDIDEC---TEMCPINSTCTNTPGSYFCTCHPGF 268
Score = 72.9 bits (171), Expect = 4e-12
Identities = 45/130 (34%), Positives = 62/130 (47%), Gaps = 29/130 (22%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGY-----------RPAGEVCADVDEC--- 784
D+DEC+ P C P GR++C C G+ +P C D++EC
Sbjct: 98 DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTS 157
Query: 785 AVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGS 842
+V P D C N+ GSY C C+ G+ + C DVDEC D C + C+NT G+
Sbjct: 158 SVCPEHSD--CVNSMGSYSCSCQVGFI--SRNSTCEDVDECA-DPRACPEHATCNNTVGN 212
Query: 843 YECSCEDGYE 852
Y C C G+E
Sbjct: 213 YSCFCNPGFE 222
Score = 61.3 bits (142), Expect = 1e-08
Identities = 32/101 (31%), Positives = 46/101 (45%), Gaps = 14/101 (13%)
Query: 771 YRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGA---------NC 819
++ G C D+DEC+ P PC + C N G Y C C G+ +C
Sbjct: 89 FKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSC 148
Query: 820 RDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDAC 858
D++EC + C + C N+ GSY CSC+ G+ R C
Sbjct: 149 TDINECLTSS-VCPEHSDCVNSMGSYSCSCQVGFISRNSTC 188
Score = 58.0 bits (134), Expect = 1e-07
Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 16/104 (15%)
Query: 747 DVDECAA---IPGLCA--PGRFRCVCGPGYRPA---------GEVCADVDECAVRPPPC- 791
D+DEC I C PG + C C PG+ P+ G C D+DEC P C
Sbjct: 239 DIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCG 298
Query: 792 -DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ 834
+ +C N GSY C C G+ + +G+ C+R C++
Sbjct: 299 PNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKE 342
Score = 56.0 bits (129), Expect = 5e-07
Identities = 29/86 (33%), Positives = 37/86 (43%), Gaps = 14/86 (16%)
Query: 775 GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY-------ELDEDGANCRDVDECER 827
G C D C P C NT SY C C+ G+ + G C+D+DEC +
Sbjct: 50 GNNCRDSTLC-----PAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQ 104
Query: 828 DTHTC--QQICSNTEGSYECSCEDGY 851
C C N G Y+CSC DG+
Sbjct: 105 SPQPCGPNSSCKNLSGRYKCSCLDGF 130
>X81479-1|CAA57232.1| 886|Homo sapiens EMR1 protein.
Length = 886
Score = 178 bits (433), Expect = 8e-44
Identities = 94/259 (36%), Positives = 126/259 (48%), Gaps = 36/259 (13%)
Query: 82 TCHDTPTGFQCGCDHGYEHDN-TSHL------CRDVDECSWGRPPCRGMAQCVNLPGAFE 134
TC +T + C C G+ N +H C+D+DECS PC + C NL G ++
Sbjct: 46 TCTNTVDSYYCTCKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYK 105
Query: 135 CRCPPGYRLTPSLD---------ECEDVDECGDQRIC-DHGDCRNTIGSYRCECKPGYTL 184
C C G+ D C D++EC R+C +H DC N++GSY C C+ G+
Sbjct: 106 CSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSRVCPEHSDCVNSMGSYSCSCQVGFIS 165
Query: 185 RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA--------GPNNDCVDVNEC 236
R + C DV+EC+ PR + TC N G Y C C+ GF++ G C D++EC
Sbjct: 166 RNSTCEDVNECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSCQGLKASCEDIDEC 225
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGY-------TLTADGRNCRDVDECDELPHPCGRDG 289
E M N C NT GS+ C C PG+ T G CRD+DEC + P CG
Sbjct: 226 TE--MCPINSTCTNTPGSYFCTCHPGFAPSSGQLNFTDQGVECRDIDECRQDPSTCG--P 281
Query: 290 NPSCTNTNGGYECSCGAGW 308
N CTN G Y C C G+
Sbjct: 282 NSICTNALGSYSCGCIVGF 300
Score = 142 bits (344), Expect = 5e-33
Identities = 84/255 (32%), Positives = 115/255 (45%), Gaps = 34/255 (13%)
Query: 66 KPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHL---------CRDVDECSW 115
K IDEC PQ C P + C + ++C C G+ + C D++EC
Sbjct: 79 KDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLT 138
Query: 116 GRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRIC-DHGDCRNTIGSY 174
R C + CVN G++ C C G+ S CEDV+EC D R C +H C NT+G+Y
Sbjct: 139 SRV-CPEHSDCVNSMGSYSCSCQVGFISRNST--CEDVNECADPRACPEHATCNNTVGNY 195
Query: 175 RCECKPGYTLREN---------VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF--K 223
C C PG+ C D+DEC+ P+ N TC N PG+Y C C GF
Sbjct: 196 SCFCNPGFESSSGHLSCQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGFAPS 253
Query: 224 AGPNN------DCVDVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTLTADGRNCRDVD 276
+G N +C D++ECR+ C N C N +GS+ C C G+ +G
Sbjct: 254 SGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIVGFHPNPEGSQKDGNF 313
Query: 277 ECDELPHPCGRDGNP 291
C + C D P
Sbjct: 314 SCQRVLFKCKEDVIP 328
Score = 141 bits (341), Expect = 1e-32
Identities = 81/234 (34%), Positives = 111/234 (47%), Gaps = 30/234 (12%)
Query: 425 QDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLA---------PDGLSCVDADECAL 474
+D+DEC P C C N G ++C C DG+ P SC D +EC L
Sbjct: 79 KDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-L 137
Query: 475 DPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFR 532
R+C + C N+ G Y C C GF + TC DV+ECA+ RA C+NT G++
Sbjct: 138 TSRVCPEHSDCVNSMGSYSCSCQVGFI-SRNSTCEDVNECADPRACPEHATCNNTVGNYS 196
Query: 533 CTCPYGYA-----VAADGV--HCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRT 583
C C G+ ++ G+ C DIDEC + +CP C N GSY C C G+ +
Sbjct: 197 CFCNPGFESSSGHLSCQGLKASCEDIDECTE---MCPINSTCTNTPGSYFCTCHPGFAPS 253
Query: 584 SAP---QDSENACEDINECEEQEDLCS-GGVCINTDGSFLCDCDAGFEPSEDGT 633
S D C DI+EC + C +C N GS+ C C GF P+ +G+
Sbjct: 254 SGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIVGFHPNPEGS 307
Score = 136 bits (328), Expect = 4e-31
Identities = 79/221 (35%), Positives = 112/221 (50%), Gaps = 29/221 (13%)
Query: 442 CVNTDGSFRCECPDGYVLA-------PDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
C NT S+ C C G++ + G+ C D DEC+ P+ CG N +C N G Y+C
Sbjct: 47 CTNTVDSYYCTCKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKC 106
Query: 494 QCSPGFTQ--GPDQ--------TCVDVDECAEGRASCTFR-CHNTAGSFRCTCPYGYAVA 542
C GF+ G D +C D++EC R C N+ GS+ C+C G+ ++
Sbjct: 107 SCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSRVCPEHSDCVNSMGSYSCSCQVGF-IS 165
Query: 543 ADGVHCRDIDECVQEPRVCP-HA-CENVVGSYICKCPEGYRRTSAP---QDSENACEDIN 597
+ C D++EC +PR CP HA C N VG+Y C C G+ +S Q + +CEDI+
Sbjct: 166 RNST-CEDVNECA-DPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSCQGLKASCEDID 223
Query: 598 ECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDR 638
EC E + S C NT GS+ C C GF PS + D+
Sbjct: 224 ECTEMCPINS--TCTNTPGSYFCTCHPGFAPSSGQLNFTDQ 262
Score = 130 bits (314), Expect = 2e-29
Identities = 83/266 (31%), Positives = 115/266 (43%), Gaps = 43/266 (16%)
Query: 120 CRGMAQCVNLPGAFECRCPPGYRLTPSLD-------ECEDVDECGD--QRICDHGDCRNT 170
C A C N ++ C C G+ + + C+D+DEC Q + C+N
Sbjct: 41 CPAYATCTNTVDSYYCTCKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNL 100
Query: 171 IGSYRCECKPGYTLREN-----------VCRDVDECSRPRPVCRNGTCENLPGAYLCHCD 219
G Y+C C G++ C D++EC R + C N G+Y C C
Sbjct: 101 SGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSRVCPEHSDCVNSMGSYSCSCQ 160
Query: 220 DGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYT-----LTADG--RNC 272
GF N+ C DVNEC + + C NTVG++ C C PG+ L+ G +C
Sbjct: 161 VGF-ISRNSTCEDVNECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSCQGLKASC 219
Query: 273 RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL---------VGRRCVDRDECKE 323
D+DEC E+ C N +CTNT G Y C+C G+ G C D DEC++
Sbjct: 220 EDIDECTEM---C--PINSTCTNTPGSYFCTCHPGFAPSSGQLNFTDQGVECRDIDECRQ 274
Query: 324 LPYVCAGGE-CRNFNGGYVCECPAGW 348
P C C N G Y C C G+
Sbjct: 275 DPSTCGPNSICTNALGSYSCGCIVGF 300
Score = 126 bits (304), Expect = 3e-28
Identities = 98/306 (32%), Positives = 137/306 (44%), Gaps = 37/306 (12%)
Query: 319 DECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRAR 378
+ C++ A C N Y C C G+ D C D E C ++
Sbjct: 33 NNCRDSTLCPAYATCTNTVDSYYCTCKQGFLSSNGQNHFKDPGVR-CKDIDE---CSQSP 88
Query: 379 PLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRP-NLT-QDLDECRVRPDV 436
Q P C + GRY +C D G+P N + D++EC
Sbjct: 89 --QPCGPNSSCKNLS--GRY--KCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSRVC 142
Query: 437 CVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQC 495
CVN+ GS+ C C G++ +C D +ECA DPR C + TC+NT G Y C C
Sbjct: 143 PEHSDCVNSMGSYSCSCQVGFISRNS--TCEDVNECA-DPRACPEHATCNNTVGNYSCFC 199
Query: 496 SPGF--------TQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAA---- 543
+PGF QG +C D+DEC E C NT GS+ CTC G+A ++
Sbjct: 200 NPGFESSSGHLSCQGLKASCEDIDECTE-MCPINSTCTNTPGSYFCTCHPGFAPSSGQLN 258
Query: 544 ---DGVHCRDIDECVQEPRVC-PHA-CENVVGSYICKCPEGYRRT--SAPQDSENACEDI 596
GV CRDIDEC Q+P C P++ C N +GSY C C G+ + +D +C+ +
Sbjct: 259 FTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIVGFHPNPEGSQKDGNFSCQRV 318
Query: 597 -NECEE 601
+C+E
Sbjct: 319 LFKCKE 324
Score = 125 bits (301), Expect = 8e-28
Identities = 73/225 (32%), Positives = 103/225 (45%), Gaps = 37/225 (16%)
Query: 154 DECGDQRICD-HGDCRNTIGSYRCECKPGYTLRENV---------CRDVDECSR-PRPVC 202
+ C D +C + C NT+ SY C CK G+ C+D+DECS+ P+P
Sbjct: 33 NNCRDSTLCPAYATCTNTVDSYYCTCKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
Query: 203 RNGTCENLPGAYLCHCDDGFKAGPNND----------CVDVNECREGGMVCRNGRCRNTV 252
N +C+NL G Y C C DGF + ND C D+NEC + + C N++
Sbjct: 93 PNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSRVCPEHSDCVNSM 152
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL-- 310
GS+ C C G+ + C DV+EC + P C + +C NT G Y C C G++
Sbjct: 153 GSYSCSCQVGF--ISRNSTCEDVNECAD-PRACPE--HATCNNTVGNYSCFCNPGFESSS 207
Query: 311 -------VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
+ C D DEC E+ + C N G Y C C G+
Sbjct: 208 GHLSCQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGF 250
Score = 99.1 bits (236), Expect = 6e-20
Identities = 61/183 (33%), Positives = 84/183 (45%), Gaps = 29/183 (15%)
Query: 475 DPRIC-GNGTCSNTRGGYECQCSPGFTQG--------PDQTCVDVDECAEGRASC--TFR 523
D +C TC+NT Y C C GF P C D+DEC++ C
Sbjct: 37 DSTLCPAYATCTNTVDSYYCTCKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSS 96
Query: 524 CHNTAGSFRCTCPYGYA--VAADGV-------HCRDIDECVQEPRVCP-HA-CENVVGSY 572
C N +G ++C+C G++ D V C DI+EC+ RVCP H+ C N +GSY
Sbjct: 97 CKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTS-RVCPEHSDCVNSMGSY 155
Query: 573 ICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDG 632
C C G+ ++ CED+NEC + C NT G++ C C+ GFE S
Sbjct: 156 SCSCQVGFISRNS------TCEDVNECADPRACPEHATCNNTVGNYSCFCNPGFESSSGH 209
Query: 633 TDC 635
C
Sbjct: 210 LSC 212
Score = 97.9 bits (233), Expect = 1e-19
Identities = 83/297 (27%), Positives = 112/297 (37%), Gaps = 43/297 (14%)
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG--------PNNDCVDVNECRE 238
N CRD C TC N +Y C C GF + P C D++EC +
Sbjct: 33 NNCRDSTLCPA------YATCTNTVDSYYCTCKQGFLSSNGQNHFKDPGVRCKDIDECSQ 86
Query: 239 GGMVCR-NGRCRNTVGSFRCECAPGYTLTAD-----GR----NCRDVDECDELPHPCGRD 288
C N C+N G ++C C G++ G+ +C D++EC C
Sbjct: 87 SPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-LTSRVCPEH 145
Query: 289 GNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVC-AGGECRNFNGGYVCECPAG 347
+ C N+ G Y CSC G+ C D +EC + P C C N G Y C C G
Sbjct: 146 SD--CVNSMGSYSCSCQVGFISRNSTCEDVNECAD-PRACPEHATCNNTVGNYSCFCNPG 202
Query: 348 WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS 407
+ C K C D C P+ C + ++ C AP S
Sbjct: 203 FESSSGHLSC-QGLKASCED---IDECTEMCPIN----STCTNTPGSYFCTCHPGFAPSS 254
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDG 463
+ QG R D+DECR P C C N GS+ C C G+ P+G
Sbjct: 255 GQLNFTDQGVECR-----DIDECRQDPSTCGPNSICTNALGSYSCGCIVGFHPNPEG 306
Score = 79.4 bits (187), Expect = 5e-14
Identities = 48/130 (36%), Positives = 61/130 (46%), Gaps = 26/130 (20%)
Query: 747 DVDECA---AIP--GLC--APGRFRCVCGPGYRPA-GEV--------CADVDECAVRPPP 790
DV+ECA A P C G + C C PG+ + G + C D+DEC P
Sbjct: 172 DVNECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSCQGLKASCEDIDECT-EMCP 230
Query: 791 CDQLCHNTDGSYDCLCRTGY-------ELDEDGANCRDVDECERDTHTC--QQICSNTEG 841
+ C NT GSY C C G+ + G CRD+DEC +D TC IC+N G
Sbjct: 231 INSTCTNTPGSYFCTCHPGFAPSSGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALG 290
Query: 842 SYECSCEDGY 851
SY C C G+
Sbjct: 291 SYSCGCIVGF 300
Score = 73.7 bits (173), Expect = 2e-12
Identities = 40/101 (39%), Positives = 51/101 (50%), Gaps = 13/101 (12%)
Query: 761 GRFRCVCGPGYRPAGEVCADVDECA-VRPPPCDQLCHNTDGSYDCLCRTGYE-----LDE 814
G + C C G+ C DV+ECA R P C+NT G+Y C C G+E L
Sbjct: 153 GSYSCSCQVGFISRNSTCEDVNECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSC 212
Query: 815 DG--ANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGY 851
G A+C D+DEC T C C+NT GSY C+C G+
Sbjct: 213 QGLKASCEDIDEC---TEMCPINSTCTNTPGSYFCTCHPGF 250
Score = 72.1 bits (169), Expect = 8e-12
Identities = 43/128 (33%), Positives = 60/128 (46%), Gaps = 25/128 (19%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGY-----------RPAGEVCADVDECAV- 786
D+DEC+ P C P GR++C C G+ +P C D++EC
Sbjct: 80 DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTS 139
Query: 787 RPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 844
R P C N+ GSY C C+ G+ + C DV+EC D C + C+NT G+Y
Sbjct: 140 RVCPEHSDCVNSMGSYSCSCQVGFI--SRNSTCEDVNECA-DPRACPEHATCNNTVGNYS 196
Query: 845 CSCEDGYE 852
C C G+E
Sbjct: 197 CFCNPGFE 204
Score = 61.7 bits (143), Expect = 1e-08
Identities = 32/101 (31%), Positives = 46/101 (45%), Gaps = 14/101 (13%)
Query: 771 YRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGA---------NC 819
++ G C D+DEC+ P PC + C N G Y C C G+ +C
Sbjct: 71 FKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSC 130
Query: 820 RDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDAC 858
D++EC + C + C N+ GSY CSC+ G+ R C
Sbjct: 131 TDINEC-LTSRVCPEHSDCVNSMGSYSCSCQVGFISRNSTC 170
Score = 58.0 bits (134), Expect = 1e-07
Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 16/104 (15%)
Query: 747 DVDECAA---IPGLCA--PGRFRCVCGPGYRPA---------GEVCADVDECAVRPPPC- 791
D+DEC I C PG + C C PG+ P+ G C D+DEC P C
Sbjct: 221 DIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSSGQLNFTDQGVECRDIDECRQDPSTCG 280
Query: 792 -DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ 834
+ +C N GSY C C G+ + +G+ C+R C++
Sbjct: 281 PNSICTNALGSYSCGCIVGFHPNPEGSQKDGNFSCQRVLFKCKE 324
Score = 56.0 bits (129), Expect = 5e-07
Identities = 29/86 (33%), Positives = 37/86 (43%), Gaps = 14/86 (16%)
Query: 775 GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY-------ELDEDGANCRDVDECER 827
G C D C P C NT SY C C+ G+ + G C+D+DEC +
Sbjct: 32 GNNCRDSTLC-----PAYATCTNTVDSYYCTCKQGFLSSNGQNHFKDPGVRCKDIDECSQ 86
Query: 828 DTHTC--QQICSNTEGSYECSCEDGY 851
C C N G Y+CSC DG+
Sbjct: 87 SPQPCGPNSSCKNLSGRYKCSCLDGF 112
>AF124486-1|AAG45245.1| 443|Homo sapiens fibulin-like extracellular
matrix protein protein.
Length = 443
Score = 172 bits (418), Expect = 5e-42
Identities = 93/212 (43%), Positives = 117/212 (55%), Gaps = 17/212 (8%)
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICDHG---DCRNTIGSYRCECKPGYTLRENVCRDVD 193
CPPGY D C DVDEC Q + D DC N GSY+C C GY C D+D
Sbjct: 109 CPPGYE-PDDQDSCVDVDECA-QALHDRRPSQDCHNLSGSYQCTCPDGYRKIGPECVDID 166
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTV 252
EC R R C++ C NLPG++ C C+ GF+ GPNN CVDVNEC + G C RC N+
Sbjct: 167 EC-RYR-YCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSY 221
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
G+F C C GY L DG +C D+DEC + C C N G + C C G++L+
Sbjct: 222 GTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC----QYRCVNEPGRFSCHCPQGYQLLA 277
Query: 313 RR-CVDRDECKELPYVCAGGE-CRNFNGGYVC 342
R C D DEC+ + C+ + C NF+GGY C
Sbjct: 278 TRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 160 bits (389), Expect = 2e-38
Identities = 85/207 (41%), Positives = 109/207 (52%), Gaps = 15/207 (7%)
Query: 426 DLDEC-RVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTC 484
D+DEC + D C N GS++C CPDGY G CVD DEC R C + C
Sbjct: 123 DVDECAQALHDRRPSQDCHNLSGSYQCTCPDGY--RKIGPECVDIDECRY--RYCQH-RC 177
Query: 485 SNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAA 543
N G + CQC PGF GP+ ++CVDV+EC G A C RC N+ G+F C C GY +
Sbjct: 178 VNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMG-APCEQRCFNSYGTFLCRCHQGYELHR 236
Query: 544 DGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQE 603
DG C DIDEC +C + C N G + C CP+GY+ + C+DI+ECE
Sbjct: 237 DGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLAT-----RLCQDIDECESGA 291
Query: 604 DLCS-GGVCINTDGSFLC-DCDAGFEP 628
CS C+N G + C D + EP
Sbjct: 292 HQCSEAQTCVNFHGGYRCVDTNRCVEP 318
Score = 147 bits (357), Expect = 1e-34
Identities = 103/288 (35%), Positives = 139/288 (48%), Gaps = 33/288 (11%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GYE D S CRDV+EC C+G +C+N G + C L S D+
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC-------LPRSAAVINDL 91
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLRE-NVCRDVDECSRPRPVCR-NGTCENLP 211
G N C PGY + + C DVDEC++ R + C NL
Sbjct: 92 HGEGPPPPVPPAQHPNP-------CPPGYEPDDQDSCVDVDECAQALHDRRPSQDCHNLS 144
Query: 212 GAYLCHCDDGF-KAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G+Y C C DG+ K GP +CVD++ECR C++ RC N GSFRC+C PG+ L + R
Sbjct: 145 GSYQCTCPDGYRKIGP--ECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLGPNNR 199
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVC 328
+C DV+ECD + PC C N+ G + C C G++L G C D DEC Y+C
Sbjct: 200 SCVDVNECD-MGAPC----EQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC 254
Query: 329 AGGECRNFNGGYVCECPAGWRFDKTAAVC--VDERKELCYDEWEAGRC 374
C N G + C CP G++ T +C +DE + + EA C
Sbjct: 255 Q-YRCVNEPGRFSCHCPQGYQLLAT-RLCQDIDECESGAHQCSEAQTC 300
Score = 138 bits (335), Expect = 6e-32
Identities = 82/244 (33%), Positives = 114/244 (46%), Gaps = 20/244 (8%)
Query: 36 EACPPRGSPA-HTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCG 93
E PP PA H C P Y + +DEC +P CH+ +QC
Sbjct: 94 EGPPPPVPPAQHPNPC---PPGYEPDDQDSCVDVDECAQALHDRRPSQDCHNLSGSYQCT 150
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GY C D+DEC + C+ +CVNLPG+F C+C PG++L P+ C DV
Sbjct: 151 CPDGYRKIGPE--CVDIDECRYRY--CQH--RCVNLPGSFRCQCEPGFQLGPNNRSCVDV 204
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLP 211
+EC C+ C N+ G++ C C GY L + C D+DECS +C+ C N P
Sbjct: 205 NECDMGAPCEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-RCVNEP 262
Query: 212 GAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRC----ECAPGYTLT 266
G + CHC G++ C D++EC G C + C N G +RC C Y
Sbjct: 263 GRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQV 322
Query: 267 ADGR 270
++ R
Sbjct: 323 SENR 326
Score = 127 bits (306), Expect = 2e-28
Identities = 109/344 (31%), Positives = 143/344 (41%), Gaps = 62/344 (18%)
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVD 317
EC GY D ++CRDV+EC +P C G C N GGY C L V
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEAC--KGEMKCINHYGGYLC-------LPRSAAVI 88
Query: 318 RDECKELPYVCAGGECRNFNGGYVCECPAGWR-FDKTAAVCVDERKELCYDEWEAGRCHR 376
D E P ++ N CP G+ D+ + V VDE + +D + CH
Sbjct: 89 NDLHGEGPPPPV-PPAQHPN-----PCPPGYEPDDQDSCVDVDECAQALHDRRPSQDCHN 142
Query: 377 ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDV 436
+C C +G + + C D + R CQ
Sbjct: 143 LS----GSYQCTCPDG--YRKIGPECVDIDECRY-RYCQ-------------------HR 176
Query: 437 CVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCS 496
CV N GSFRC+C G+ L P+ SCVD +EC + C C N+ G + C+C
Sbjct: 177 CV-----NLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP-C-EQRCFNSYGTFLCRCH 229
Query: 497 PGFTQGPDQ-TCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECV 555
G+ D +C D+DEC+ C +RC N G F C CP GY + A + C+DIDEC
Sbjct: 230 QGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRL-CQDIDECE 288
Query: 556 QEPRVCPHA--CENVVGSYIC----KCPEGYRRTSAPQDSENAC 593
C A C N G Y C +C E Y Q SEN C
Sbjct: 289 SGAHQCSEAQTCVNFHGGYRCVDTNRCVEPY-----IQVSENRC 327
Score = 120 bits (288), Expect = 3e-26
Identities = 68/178 (38%), Positives = 90/178 (50%), Gaps = 15/178 (8%)
Query: 453 CPDGYVLAPDGLSCVDADEC--ALDPRICGNGTCSNTRGGYECQCSPGFTQ-GPDQTCVD 509
CP GY D SCVD DEC AL R + C N G Y+C C G+ + GP+ CVD
Sbjct: 109 CPPGYE-PDDQDSCVDVDECAQALHDR-RPSQDCHNLSGSYQCTCPDGYRKIGPE--CVD 164
Query: 510 VDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVV 569
+DEC C RC N GSFRC C G+ + + C D++EC C C N
Sbjct: 165 IDECR--YRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQRCFNSY 221
Query: 570 GSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
G+++C+C +GY +D +C DI+EC LC C+N G F C C G++
Sbjct: 222 GTFLCRCHQGY---ELHRDG-FSCSDIDECSYSSYLCQYR-CVNEPGRFSCHCPQGYQ 274
Score = 113 bits (273), Expect = 2e-24
Identities = 73/216 (33%), Positives = 102/216 (47%), Gaps = 28/216 (12%)
Query: 425 QDLDECRVRPDVCVGG-RCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT 483
+D++EC P+ C G +C+N G GY+ P + ++ P
Sbjct: 53 RDVNECLTIPEACKGEMKCINHYG--------GYLCLPRSAAVINDLHGEGPPPPVPPAQ 104
Query: 484 CSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASC--TFRCHNTAGSFRCTCPYGYAV 541
N C PG+ +CVDVDECA+ + CHN +GS++CTCP GY
Sbjct: 105 HPNP-------CPPGYEPDDQDSCVDVDECAQALHDRRPSQDCHNLSGSYQCTCPDGYRK 157
Query: 542 AADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEE 601
G C DIDEC R C H C N+ GS+ C+C G++ P + +C D+NEC+
Sbjct: 158 I--GPECVDIDEC--RYRYCQHRCVNLPGSFRCQCEPGFQL--GPNN--RSCVDVNECDM 209
Query: 602 QEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C C N+ G+FLC C G+E DG C D
Sbjct: 210 GAP-CEQR-CFNSYGTFLCRCHQGYELHRDGFSCSD 243
Score = 104 bits (249), Expect = 2e-21
Identities = 47/112 (41%), Positives = 62/112 (55%), Gaps = 7/112 (6%)
Query: 747 DVDECAA--IPGLCA--PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTDG 800
D+DEC C PG FRC C PG++ P C DV+EC + P C+Q C N+ G
Sbjct: 164 DIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP-CEQRCFNSYG 222
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
++ C C GYEL DG +C D+DEC ++ CQ C N G + C C GY+
Sbjct: 223 TFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQ 274
Score = 98.3 bits (234), Expect = 1e-19
Identities = 63/188 (33%), Positives = 81/188 (43%), Gaps = 24/188 (12%)
Query: 64 ETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGM 123
E IDEC + C+ C + P F+C C+ G++ + C DV+EC G P C
Sbjct: 161 ECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP-CE-- 214
Query: 124 AQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG-DQRICDHGDCRNTIGSYRCECKPGY 182
+C N G F CRC GY L C D+DEC +C + C N G + C C GY
Sbjct: 215 QRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYR-CVNEPGRFSCHCPQGY 273
Query: 183 TL-RENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGG 240
L +C+D+DEC C TC N G Y C VD N C E
Sbjct: 274 QLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC--------------VDTNRCVEPY 319
Query: 241 MVCRNGRC 248
+ RC
Sbjct: 320 IQVSENRC 327
Score = 91.1 bits (216), Expect = 2e-17
Identities = 46/122 (37%), Positives = 60/122 (49%), Gaps = 11/122 (9%)
Query: 743 DVFADVDECAAIPGLCAP--------GRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL 794
D DVDECA P G ++C C GYR G C D+DEC R C
Sbjct: 119 DSCVDVDECAQALHDRRPSQDCHNLSGSYQCTCPDGYRKIGPECVDIDECRYR--YCQHR 176
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
C N GS+ C C G++L + +C DV+EC+ C+Q C N+ G++ C C GYE
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGA-PCEQRCFNSYGTFLCRCHQGYELH 235
Query: 855 GD 856
D
Sbjct: 236 RD 237
Score = 71.3 bits (167), Expect = 1e-11
Identities = 41/108 (37%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query: 747 DVDEC---AAIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTD 799
DV+EC A C + G F C C GY G C+D+DEC+ C C N
Sbjct: 203 DVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEP 262
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC 845
G + C C GY+L C+D+DECE H C Q C N G Y C
Sbjct: 263 GRFSCHCPQGYQLLATRL-CQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 66.1 bits (154), Expect = 5e-10
Identities = 44/118 (37%), Positives = 55/118 (46%), Gaps = 13/118 (11%)
Query: 747 DVDECAAIPGLCAPGRFRCVCG-PGYRPAGEVCADVDECAVR--PPPCDQLCHNTDGSYD 803
DV+EC IP C G +C+ GY A +++ PPP H
Sbjct: 54 DVNECLTIPEACK-GEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNP---- 108
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACV 859
C GYE D D +C DVDEC + H + Q C N GSY+C+C DGY K G CV
Sbjct: 109 --CPPGYEPD-DQDSCVDVDECAQALHDRRPSQDCHNLSGSYQCTCPDGYRKIGPECV 163
Score = 39.5 bits (88), Expect = 0.050
Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC 845
C GYE D D +CRDV+EC C + C N G Y C
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC 80
Score = 34.7 bits (76), Expect = 1.4
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 5/47 (10%)
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLC 620
+C +GY DS++ C D+NEC + C G + CIN G +LC
Sbjct: 38 ECTDGYEWDP---DSQH-CRDVNECLTIPEACKGEMKCINHYGGYLC 80
>CR541934-1|CAG46732.1| 443|Homo sapiens EFEMP2 protein.
Length = 443
Score = 171 bits (416), Expect = 9e-42
Identities = 93/212 (43%), Positives = 117/212 (55%), Gaps = 17/212 (8%)
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICD---HGDCRNTIGSYRCECKPGYTLRENVCRDVD 193
CPPGY D C DVDEC Q + D DC N GSY+C C GY C D+D
Sbjct: 109 CPPGYE-PDDQDSCVDVDECA-QALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDID 166
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTV 252
EC R R C++ C NLPG++ C C+ GF+ GPNN CVDVNEC + G C RC N+
Sbjct: 167 EC-RYR-YCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSY 221
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
G+F C C GY L DG +C D+DEC + C C N G + C C G++L+
Sbjct: 222 GTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC----QYRCVNEPGRFSCHCPQGYQLLA 277
Query: 313 RR-CVDRDECKELPYVCAGGE-CRNFNGGYVC 342
R C D DEC+ + C+ + C NF+GGY C
Sbjct: 278 TRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 161 bits (391), Expect = 1e-38
Identities = 85/207 (41%), Positives = 109/207 (52%), Gaps = 15/207 (7%)
Query: 426 DLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTC 484
D+DEC C + C N GS++C CPDGY G CVD DEC R C + C
Sbjct: 123 DVDECAQALHDCRPSQDCHNLPGSYQCTCPDGY--RKIGPECVDIDECRY--RYCQH-RC 177
Query: 485 SNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAA 543
N G + CQC PGF GP+ ++CVDV+EC G A C RC N+ G+F C C GY +
Sbjct: 178 VNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMG-APCEQRCFNSYGTFLCRCHQGYELHR 236
Query: 544 DGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQE 603
DG C DIDEC +C + C N G + C CP+GY+ + C+DI+ECE
Sbjct: 237 DGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLAT-----RLCQDIDECESGA 291
Query: 604 DLCS-GGVCINTDGSFLC-DCDAGFEP 628
CS C+N G + C D + EP
Sbjct: 292 HQCSEAQTCVNFHGGYRCVDTNRCVEP 318
Score = 155 bits (377), Expect = 5e-37
Identities = 105/288 (36%), Positives = 141/288 (48%), Gaps = 33/288 (11%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GYE D S CRDV+EC C+G +C+N G + C L S D+
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC-------LPRSAAVINDL 91
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLRE-NVCRDVDECSRPRPVCR-NGTCENLP 211
G N C PGY + + C DVDEC++ CR + C NLP
Sbjct: 92 HGEGPPPPVPPAQHPNP-------CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLP 144
Query: 212 GAYLCHCDDGF-KAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G+Y C C DG+ K GP +CVD++ECR C++ RC N GSFRC+C PG+ L + R
Sbjct: 145 GSYQCTCPDGYRKIGP--ECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLGPNNR 199
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVC 328
+C DV+ECD + PC C N+ G + C C G++L G C D DEC Y+C
Sbjct: 200 SCVDVNECD-MGAPC----EQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC 254
Query: 329 AGGECRNFNGGYVCECPAGWRFDKTAAVC--VDERKELCYDEWEAGRC 374
C N G + C CP G++ T +C +DE + + EA C
Sbjct: 255 Q-YRCVNEPGRFSCHCPQGYQLLAT-RLCQDIDECESGAHQCSEAQTC 300
Score = 147 bits (355), Expect = 2e-34
Identities = 84/244 (34%), Positives = 116/244 (47%), Gaps = 20/244 (8%)
Query: 36 EACPPRGSPA-HTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCG 93
E PP PA H C P Y + +DEC C+P CH+ P +QC
Sbjct: 94 EGPPPPVPPAQHPNPC---PPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCT 150
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GY C D+DEC + C+ +CVNLPG+F C+C PG++L P+ C DV
Sbjct: 151 CPDGYRKIGPE--CVDIDECRYRY--CQH--RCVNLPGSFRCQCEPGFQLGPNNRSCVDV 204
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLP 211
+EC C+ C N+ G++ C C GY L + C D+DECS +C+ C N P
Sbjct: 205 NECDMGAPCEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-RCVNEP 262
Query: 212 GAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRC----ECAPGYTLT 266
G + CHC G++ C D++EC G C + C N G +RC C Y
Sbjct: 263 GRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQV 322
Query: 267 ADGR 270
++ R
Sbjct: 323 SENR 326
Score = 122 bits (295), Expect = 4e-27
Identities = 67/177 (37%), Positives = 89/177 (50%), Gaps = 13/177 (7%)
Query: 453 CPDGYVLAPDGLSCVDADECALDPRIC-GNGTCSNTRGGYECQCSPGFTQ-GPDQTCVDV 510
CP GY D SCVD DECA C + C N G Y+C C G+ + GP+ CVD+
Sbjct: 109 CPPGYE-PDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE--CVDI 165
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG 570
DEC C RC N GSFRC C G+ + + C D++EC C C N G
Sbjct: 166 DECR--YRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQRCFNSYG 222
Query: 571 SYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
+++C+C +GY +D +C DI+EC LC C+N G F C C G++
Sbjct: 223 TFLCRCHQGY---ELHRDG-FSCSDIDECSYSSYLCQYR-CVNEPGRFSCHCPQGYQ 274
Score = 118 bits (283), Expect = 1e-25
Identities = 74/216 (34%), Positives = 102/216 (47%), Gaps = 28/216 (12%)
Query: 425 QDLDECRVRPDVCVGG-RCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT 483
+D++EC P+ C G +C+N G GY+ P + ++ P
Sbjct: 53 RDVNECLTIPEACKGEMKCINHYG--------GYLCLPRSAAVINDLHGEGPPPPVPPAQ 104
Query: 484 CSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASC--TFRCHNTAGSFRCTCPYGYAV 541
N C PG+ +CVDVDECA+ C + CHN GS++CTCP GY
Sbjct: 105 HPNP-------CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK 157
Query: 542 AADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEE 601
G C DIDEC R C H C N+ GS+ C+C G++ P + +C D+NEC+
Sbjct: 158 I--GPECVDIDEC--RYRYCQHRCVNLPGSFRCQCEPGFQL--GPNN--RSCVDVNECDM 209
Query: 602 QEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C C N+ G+FLC C G+E DG C D
Sbjct: 210 GAP-CEQR-CFNSYGTFLCRCHQGYELHRDGFSCSD 243
Score = 107 bits (257), Expect = 2e-22
Identities = 89/291 (30%), Positives = 121/291 (41%), Gaps = 34/291 (11%)
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVD 317
EC GY D ++CRDV+EC +P C G C N GGY C L V
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEAC--KGEMKCINHYGGYLC-------LPRSAAVI 88
Query: 318 RDECKELPYVCAGGECRNFNGGYVCECPAGWR-FDKTAAVCVDERKELCYDEWEAGRCHR 376
D E P ++ N CP G+ D+ + V VDE + +D + CH
Sbjct: 89 NDLHGEGPPPPV-PPAQHPN-----PCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHN 142
Query: 377 ---------ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG--MGRPNLT- 424
+ PEC + + RYC+ F C+ G +G N +
Sbjct: 143 LPGSYQCTCPDGYRKIGPECVDIDECRY-RYCQHRCVNLPGSFRCQCEPGFQLGPNNRSC 201
Query: 425 QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTC 484
D++EC + C RC N+ G+F C C GY L DG SC D DEC+ +C C
Sbjct: 202 VDVNECDMGAP-C-EQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC-QYRC 258
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCT--FRCHNTAGSFRC 533
N G + C C G+ + C D+DEC G C+ C N G +RC
Sbjct: 259 VNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 104 bits (249), Expect = 2e-21
Identities = 47/112 (41%), Positives = 62/112 (55%), Gaps = 7/112 (6%)
Query: 747 DVDECAA--IPGLCA--PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTDG 800
D+DEC C PG FRC C PG++ P C DV+EC + P C+Q C N+ G
Sbjct: 164 DIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP-CEQRCFNSYG 222
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
++ C C GYEL DG +C D+DEC ++ CQ C N G + C C GY+
Sbjct: 223 TFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQ 274
Score = 95.9 bits (228), Expect = 5e-19
Identities = 47/122 (38%), Positives = 61/122 (50%), Gaps = 11/122 (9%)
Query: 743 DVFADVDECAAIPGLCAP--------GRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL 794
D DVDECA C P G ++C C GYR G C D+DEC R C
Sbjct: 119 DSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYR--YCQHR 176
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
C N GS+ C C G++L + +C DV+EC+ C+Q C N+ G++ C C GYE
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGA-PCEQRCFNSYGTFLCRCHQGYELH 235
Query: 855 GD 856
D
Sbjct: 236 RD 237
Score = 71.3 bits (167), Expect = 1e-11
Identities = 41/108 (37%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query: 747 DVDEC---AAIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTD 799
DV+EC A C + G F C C GY G C+D+DEC+ C C N
Sbjct: 203 DVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEP 262
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC 845
G + C C GY+L C+D+DECE H C Q C N G Y C
Sbjct: 263 GRFSCHCPQGYQLLATRL-CQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 70.5 bits (165), Expect = 2e-11
Identities = 45/118 (38%), Positives = 56/118 (47%), Gaps = 13/118 (11%)
Query: 747 DVDECAAIPGLCAPGRFRCVCG-PGYRPAGEVCADVDECAVR--PPPCDQLCHNTDGSYD 803
DV+EC IP C G +C+ GY A +++ PPP H
Sbjct: 54 DVNECLTIPEACK-GEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNP---- 108
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACV 859
C GYE D D +C DVDEC + H C+ Q C N GSY+C+C DGY K G CV
Sbjct: 109 --CPPGYEPD-DQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECV 163
Score = 49.6 bits (113), Expect = 5e-05
Identities = 35/128 (27%), Positives = 50/128 (39%), Gaps = 27/128 (21%)
Query: 535 CPYGYAVAADGVHCRDIDECVQEPRVC--PHACENVVGSYIC------------------ 574
C GY D HCRD++EC+ P C C N G Y+C
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPP 98
Query: 575 KCPEGYRRTSAP----QDSENACEDINECEEQ-EDLCSGGVCINTDGSFLCDCDAGFEPS 629
P P D +++C D++EC + D C N GS+ C C G+
Sbjct: 99 PVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR-- 156
Query: 630 EDGTDCID 637
+ G +C+D
Sbjct: 157 KIGPECVD 164
Score = 39.5 bits (88), Expect = 0.050
Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC 845
C GYE D D +CRDV+EC C + C N G Y C
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC 80
Score = 34.7 bits (76), Expect = 1.4
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 5/47 (10%)
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLC 620
+C +GY DS++ C D+NEC + C G + CIN G +LC
Sbjct: 38 ECTDGYEWDP---DSQH-CRDVNECLTIPEACKGEMKCINHYGGYLC 80
>BC010456-1|AAH10456.1| 443|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 2 protein.
Length = 443
Score = 171 bits (416), Expect = 9e-42
Identities = 93/212 (43%), Positives = 117/212 (55%), Gaps = 17/212 (8%)
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICD---HGDCRNTIGSYRCECKPGYTLRENVCRDVD 193
CPPGY D C DVDEC Q + D DC N GSY+C C GY C D+D
Sbjct: 109 CPPGYE-PDDQDSCVDVDECA-QALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDID 166
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTV 252
EC R R C++ C NLPG++ C C+ GF+ GPNN CVDVNEC + G C RC N+
Sbjct: 167 EC-RYR-YCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSY 221
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
G+F C C GY L DG +C D+DEC + C C N G + C C G++L+
Sbjct: 222 GTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC----QYRCVNEPGRFSCHCPQGYQLLA 277
Query: 313 RR-CVDRDECKELPYVCAGGE-CRNFNGGYVC 342
R C D DEC+ + C+ + C NF+GGY C
Sbjct: 278 TRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 161 bits (391), Expect = 1e-38
Identities = 85/207 (41%), Positives = 109/207 (52%), Gaps = 15/207 (7%)
Query: 426 DLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTC 484
D+DEC C + C N GS++C CPDGY G CVD DEC R C + C
Sbjct: 123 DVDECAQALHDCRPSQDCHNLPGSYQCTCPDGY--RKIGPECVDIDECRY--RYCQH-RC 177
Query: 485 SNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAA 543
N G + CQC PGF GP+ ++CVDV+EC G A C RC N+ G+F C C GY +
Sbjct: 178 VNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMG-APCEQRCFNSYGTFLCRCHQGYELHR 236
Query: 544 DGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQE 603
DG C DIDEC +C + C N G + C CP+GY+ + C+DI+ECE
Sbjct: 237 DGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLAT-----RLCQDIDECESGA 291
Query: 604 DLCS-GGVCINTDGSFLC-DCDAGFEP 628
CS C+N G + C D + EP
Sbjct: 292 HQCSEAQTCVNFHGGYRCVDTNRCVEP 318
Score = 155 bits (377), Expect = 5e-37
Identities = 105/288 (36%), Positives = 141/288 (48%), Gaps = 33/288 (11%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GYE D S CRDV+EC C+G +C+N G + C L S D+
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC-------LPRSAAVINDL 91
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLRE-NVCRDVDECSRPRPVCR-NGTCENLP 211
G N C PGY + + C DVDEC++ CR + C NLP
Sbjct: 92 HGEGPPPPVPPAQHPNP-------CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLP 144
Query: 212 GAYLCHCDDGF-KAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G+Y C C DG+ K GP +CVD++ECR C++ RC N GSFRC+C PG+ L + R
Sbjct: 145 GSYQCTCPDGYRKIGP--ECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLGPNNR 199
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVC 328
+C DV+ECD + PC C N+ G + C C G++L G C D DEC Y+C
Sbjct: 200 SCVDVNECD-MGAPC----EQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC 254
Query: 329 AGGECRNFNGGYVCECPAGWRFDKTAAVC--VDERKELCYDEWEAGRC 374
C N G + C CP G++ T +C +DE + + EA C
Sbjct: 255 Q-YRCVNEPGRFSCHCPQGYQLLAT-RLCQDIDECESGAHQCSEAQTC 300
Score = 147 bits (355), Expect = 2e-34
Identities = 84/244 (34%), Positives = 116/244 (47%), Gaps = 20/244 (8%)
Query: 36 EACPPRGSPA-HTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCG 93
E PP PA H C P Y + +DEC C+P CH+ P +QC
Sbjct: 94 EGPPPPVPPAQHPNPC---PPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCT 150
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GY C D+DEC + C+ +CVNLPG+F C+C PG++L P+ C DV
Sbjct: 151 CPDGYRKIGPE--CVDIDECRYRY--CQH--RCVNLPGSFRCQCEPGFQLGPNNRSCVDV 204
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLP 211
+EC C+ C N+ G++ C C GY L + C D+DECS +C+ C N P
Sbjct: 205 NECDMGAPCEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-RCVNEP 262
Query: 212 GAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRC----ECAPGYTLT 266
G + CHC G++ C D++EC G C + C N G +RC C Y
Sbjct: 263 GRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQV 322
Query: 267 ADGR 270
++ R
Sbjct: 323 SENR 326
Score = 122 bits (295), Expect = 4e-27
Identities = 67/177 (37%), Positives = 89/177 (50%), Gaps = 13/177 (7%)
Query: 453 CPDGYVLAPDGLSCVDADECALDPRIC-GNGTCSNTRGGYECQCSPGFTQ-GPDQTCVDV 510
CP GY D SCVD DECA C + C N G Y+C C G+ + GP+ CVD+
Sbjct: 109 CPPGYE-PDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE--CVDI 165
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG 570
DEC C RC N GSFRC C G+ + + C D++EC C C N G
Sbjct: 166 DECR--YRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQRCFNSYG 222
Query: 571 SYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
+++C+C +GY +D +C DI+EC LC C+N G F C C G++
Sbjct: 223 TFLCRCHQGY---ELHRDG-FSCSDIDECSYSSYLCQYR-CVNEPGRFSCHCPQGYQ 274
Score = 118 bits (283), Expect = 1e-25
Identities = 74/216 (34%), Positives = 102/216 (47%), Gaps = 28/216 (12%)
Query: 425 QDLDECRVRPDVCVGG-RCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT 483
+D++EC P+ C G +C+N G GY+ P + ++ P
Sbjct: 53 RDVNECLTIPEACKGEMKCINHYG--------GYLCLPRSAAVINDLHGEGPPPPVPPAQ 104
Query: 484 CSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASC--TFRCHNTAGSFRCTCPYGYAV 541
N C PG+ +CVDVDECA+ C + CHN GS++CTCP GY
Sbjct: 105 HPNP-------CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK 157
Query: 542 AADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEE 601
G C DIDEC R C H C N+ GS+ C+C G++ P + +C D+NEC+
Sbjct: 158 I--GPECVDIDEC--RYRYCQHRCVNLPGSFRCQCEPGFQL--GPNN--RSCVDVNECDM 209
Query: 602 QEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C C N+ G+FLC C G+E DG C D
Sbjct: 210 GAP-CEQR-CFNSYGTFLCRCHQGYELHRDGFSCSD 243
Score = 107 bits (257), Expect = 2e-22
Identities = 89/291 (30%), Positives = 121/291 (41%), Gaps = 34/291 (11%)
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVD 317
EC GY D ++CRDV+EC +P C G C N GGY C L V
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEAC--KGEMKCINHYGGYLC-------LPRSAAVI 88
Query: 318 RDECKELPYVCAGGECRNFNGGYVCECPAGWR-FDKTAAVCVDERKELCYDEWEAGRCHR 376
D E P ++ N CP G+ D+ + V VDE + +D + CH
Sbjct: 89 NDLHGEGPPPPV-PPAQHPN-----PCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHN 142
Query: 377 ---------ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG--MGRPNLT- 424
+ PEC + + RYC+ F C+ G +G N +
Sbjct: 143 LPGSYQCTCPDGYRKIGPECVDIDECRY-RYCQHRCVNLPGSFRCQCEPGFQLGPNNRSC 201
Query: 425 QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTC 484
D++EC + C RC N+ G+F C C GY L DG SC D DEC+ +C C
Sbjct: 202 VDVNECDMGAP-C-EQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC-QYRC 258
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCT--FRCHNTAGSFRC 533
N G + C C G+ + C D+DEC G C+ C N G +RC
Sbjct: 259 VNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 104 bits (249), Expect = 2e-21
Identities = 47/112 (41%), Positives = 62/112 (55%), Gaps = 7/112 (6%)
Query: 747 DVDECAA--IPGLCA--PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTDG 800
D+DEC C PG FRC C PG++ P C DV+EC + P C+Q C N+ G
Sbjct: 164 DIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP-CEQRCFNSYG 222
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
++ C C GYEL DG +C D+DEC ++ CQ C N G + C C GY+
Sbjct: 223 TFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQ 274
Score = 95.9 bits (228), Expect = 5e-19
Identities = 47/122 (38%), Positives = 61/122 (50%), Gaps = 11/122 (9%)
Query: 743 DVFADVDECAAIPGLCAP--------GRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL 794
D DVDECA C P G ++C C GYR G C D+DEC R C
Sbjct: 119 DSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYR--YCQHR 176
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
C N GS+ C C G++L + +C DV+EC+ C+Q C N+ G++ C C GYE
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGA-PCEQRCFNSYGTFLCRCHQGYELH 235
Query: 855 GD 856
D
Sbjct: 236 RD 237
Score = 71.3 bits (167), Expect = 1e-11
Identities = 41/108 (37%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query: 747 DVDEC---AAIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTD 799
DV+EC A C + G F C C GY G C+D+DEC+ C C N
Sbjct: 203 DVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEP 262
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC 845
G + C C GY+L C+D+DECE H C Q C N G Y C
Sbjct: 263 GRFSCHCPQGYQLLATRL-CQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 70.5 bits (165), Expect = 2e-11
Identities = 45/118 (38%), Positives = 56/118 (47%), Gaps = 13/118 (11%)
Query: 747 DVDECAAIPGLCAPGRFRCVCG-PGYRPAGEVCADVDECAVR--PPPCDQLCHNTDGSYD 803
DV+EC IP C G +C+ GY A +++ PPP H
Sbjct: 54 DVNECLTIPEACK-GEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNP---- 108
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACV 859
C GYE D D +C DVDEC + H C+ Q C N GSY+C+C DGY K G CV
Sbjct: 109 --CPPGYEPD-DQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECV 163
Score = 49.6 bits (113), Expect = 5e-05
Identities = 35/128 (27%), Positives = 50/128 (39%), Gaps = 27/128 (21%)
Query: 535 CPYGYAVAADGVHCRDIDECVQEPRVC--PHACENVVGSYIC------------------ 574
C GY D HCRD++EC+ P C C N G Y+C
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPP 98
Query: 575 KCPEGYRRTSAP----QDSENACEDINECEEQ-EDLCSGGVCINTDGSFLCDCDAGFEPS 629
P P D +++C D++EC + D C N GS+ C C G+
Sbjct: 99 PVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR-- 156
Query: 630 EDGTDCID 637
+ G +C+D
Sbjct: 157 KIGPECVD 164
Score = 39.5 bits (88), Expect = 0.050
Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC 845
C GYE D D +CRDV+EC C + C N G Y C
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC 80
Score = 34.7 bits (76), Expect = 1.4
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 5/47 (10%)
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLC 620
+C +GY DS++ C D+NEC + C G + CIN G +LC
Sbjct: 38 ECTDGYEWDP---DSQH-CRDVNECLTIPEACKGEMKCINHYGGYLC 80
>AY358899-1|AAQ89258.1| 443|Homo sapiens EFEMP2 protein.
Length = 443
Score = 171 bits (416), Expect = 9e-42
Identities = 93/212 (43%), Positives = 117/212 (55%), Gaps = 17/212 (8%)
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICD---HGDCRNTIGSYRCECKPGYTLRENVCRDVD 193
CPPGY D C DVDEC Q + D DC N GSY+C C GY C D+D
Sbjct: 109 CPPGYE-PDDQDSCVDVDECA-QALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDID 166
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTV 252
EC R R C++ C NLPG++ C C+ GF+ GPNN CVDVNEC + G C RC N+
Sbjct: 167 EC-RYR-YCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSY 221
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
G+F C C GY L DG +C D+DEC + C C N G + C C G++L+
Sbjct: 222 GTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC----QYRCVNEPGRFSCHCPQGYQLLA 277
Query: 313 RR-CVDRDECKELPYVCAGGE-CRNFNGGYVC 342
R C D DEC+ + C+ + C NF+GGY C
Sbjct: 278 TRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 161 bits (391), Expect = 1e-38
Identities = 85/207 (41%), Positives = 109/207 (52%), Gaps = 15/207 (7%)
Query: 426 DLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTC 484
D+DEC C + C N GS++C CPDGY G CVD DEC R C + C
Sbjct: 123 DVDECAQALHDCRPSQDCHNLPGSYQCTCPDGY--RKIGPECVDIDECRY--RYCQH-RC 177
Query: 485 SNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAA 543
N G + CQC PGF GP+ ++CVDV+EC G A C RC N+ G+F C C GY +
Sbjct: 178 VNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMG-APCEQRCFNSYGTFLCRCHQGYELHR 236
Query: 544 DGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQE 603
DG C DIDEC +C + C N G + C CP+GY+ + C+DI+ECE
Sbjct: 237 DGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLAT-----RLCQDIDECESGA 291
Query: 604 DLCS-GGVCINTDGSFLC-DCDAGFEP 628
CS C+N G + C D + EP
Sbjct: 292 HQCSEAQTCVNFHGGYRCVDTNRCVEP 318
Score = 155 bits (377), Expect = 5e-37
Identities = 105/288 (36%), Positives = 141/288 (48%), Gaps = 33/288 (11%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GYE D S CRDV+EC C+G +C+N G + C L S D+
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC-------LPRSAAVINDL 91
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLRE-NVCRDVDECSRPRPVCR-NGTCENLP 211
G N C PGY + + C DVDEC++ CR + C NLP
Sbjct: 92 HGEGPPPPVPPAQHPNP-------CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLP 144
Query: 212 GAYLCHCDDGF-KAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G+Y C C DG+ K GP +CVD++ECR C++ RC N GSFRC+C PG+ L + R
Sbjct: 145 GSYQCTCPDGYRKIGP--ECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLGPNNR 199
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVC 328
+C DV+ECD + PC C N+ G + C C G++L G C D DEC Y+C
Sbjct: 200 SCVDVNECD-MGAPC----EQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC 254
Query: 329 AGGECRNFNGGYVCECPAGWRFDKTAAVC--VDERKELCYDEWEAGRC 374
C N G + C CP G++ T +C +DE + + EA C
Sbjct: 255 Q-YRCVNEPGRFSCHCPQGYQLLAT-RLCQDIDECESGAHQCSEAQTC 300
Score = 147 bits (355), Expect = 2e-34
Identities = 84/244 (34%), Positives = 116/244 (47%), Gaps = 20/244 (8%)
Query: 36 EACPPRGSPA-HTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCG 93
E PP PA H C P Y + +DEC C+P CH+ P +QC
Sbjct: 94 EGPPPPVPPAQHPNPC---PPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCT 150
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GY C D+DEC + C+ +CVNLPG+F C+C PG++L P+ C DV
Sbjct: 151 CPDGYRKIGPE--CVDIDECRYRY--CQH--RCVNLPGSFRCQCEPGFQLGPNNRSCVDV 204
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLP 211
+EC C+ C N+ G++ C C GY L + C D+DECS +C+ C N P
Sbjct: 205 NECDMGAPCEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-RCVNEP 262
Query: 212 GAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRC----ECAPGYTLT 266
G + CHC G++ C D++EC G C + C N G +RC C Y
Sbjct: 263 GRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQV 322
Query: 267 ADGR 270
++ R
Sbjct: 323 SENR 326
Score = 122 bits (295), Expect = 4e-27
Identities = 67/177 (37%), Positives = 89/177 (50%), Gaps = 13/177 (7%)
Query: 453 CPDGYVLAPDGLSCVDADECALDPRIC-GNGTCSNTRGGYECQCSPGFTQ-GPDQTCVDV 510
CP GY D SCVD DECA C + C N G Y+C C G+ + GP+ CVD+
Sbjct: 109 CPPGYE-PDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE--CVDI 165
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG 570
DEC C RC N GSFRC C G+ + + C D++EC C C N G
Sbjct: 166 DECR--YRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQRCFNSYG 222
Query: 571 SYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
+++C+C +GY +D +C DI+EC LC C+N G F C C G++
Sbjct: 223 TFLCRCHQGY---ELHRDG-FSCSDIDECSYSSYLCQYR-CVNEPGRFSCHCPQGYQ 274
Score = 118 bits (283), Expect = 1e-25
Identities = 74/216 (34%), Positives = 102/216 (47%), Gaps = 28/216 (12%)
Query: 425 QDLDECRVRPDVCVGG-RCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT 483
+D++EC P+ C G +C+N G GY+ P + ++ P
Sbjct: 53 RDVNECLTIPEACKGEMKCINHYG--------GYLCLPRSAAVINDLHGEGPPPPVPPAQ 104
Query: 484 CSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASC--TFRCHNTAGSFRCTCPYGYAV 541
N C PG+ +CVDVDECA+ C + CHN GS++CTCP GY
Sbjct: 105 HPNP-------CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK 157
Query: 542 AADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEE 601
G C DIDEC R C H C N+ GS+ C+C G++ P + +C D+NEC+
Sbjct: 158 I--GPECVDIDEC--RYRYCQHRCVNLPGSFRCQCEPGFQL--GPNN--RSCVDVNECDM 209
Query: 602 QEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C C N+ G+FLC C G+E DG C D
Sbjct: 210 GAP-CEQR-CFNSYGTFLCRCHQGYELHRDGFSCSD 243
Score = 107 bits (257), Expect = 2e-22
Identities = 89/291 (30%), Positives = 121/291 (41%), Gaps = 34/291 (11%)
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVD 317
EC GY D ++CRDV+EC +P C G C N GGY C L V
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEAC--KGEMKCINHYGGYLC-------LPRSAAVI 88
Query: 318 RDECKELPYVCAGGECRNFNGGYVCECPAGWR-FDKTAAVCVDERKELCYDEWEAGRCHR 376
D E P ++ N CP G+ D+ + V VDE + +D + CH
Sbjct: 89 NDLHGEGPPPPV-PPAQHPN-----PCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHN 142
Query: 377 ---------ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG--MGRPNLT- 424
+ PEC + + RYC+ F C+ G +G N +
Sbjct: 143 LPGSYQCTCPDGYRKIGPECVDIDECRY-RYCQHRCVNLPGSFRCQCEPGFQLGPNNRSC 201
Query: 425 QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTC 484
D++EC + C RC N+ G+F C C GY L DG SC D DEC+ +C C
Sbjct: 202 VDVNECDMGAP-C-EQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC-QYRC 258
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCT--FRCHNTAGSFRC 533
N G + C C G+ + C D+DEC G C+ C N G +RC
Sbjct: 259 VNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 104 bits (249), Expect = 2e-21
Identities = 47/112 (41%), Positives = 62/112 (55%), Gaps = 7/112 (6%)
Query: 747 DVDECAA--IPGLCA--PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTDG 800
D+DEC C PG FRC C PG++ P C DV+EC + P C+Q C N+ G
Sbjct: 164 DIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP-CEQRCFNSYG 222
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
++ C C GYEL DG +C D+DEC ++ CQ C N G + C C GY+
Sbjct: 223 TFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQ 274
Score = 95.9 bits (228), Expect = 5e-19
Identities = 47/122 (38%), Positives = 61/122 (50%), Gaps = 11/122 (9%)
Query: 743 DVFADVDECAAIPGLCAP--------GRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL 794
D DVDECA C P G ++C C GYR G C D+DEC R C
Sbjct: 119 DSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYR--YCQHR 176
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
C N GS+ C C G++L + +C DV+EC+ C+Q C N+ G++ C C GYE
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGA-PCEQRCFNSYGTFLCRCHQGYELH 235
Query: 855 GD 856
D
Sbjct: 236 RD 237
Score = 71.3 bits (167), Expect = 1e-11
Identities = 41/108 (37%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query: 747 DVDEC---AAIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTD 799
DV+EC A C + G F C C GY G C+D+DEC+ C C N
Sbjct: 203 DVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEP 262
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC 845
G + C C GY+L C+D+DECE H C Q C N G Y C
Sbjct: 263 GRFSCHCPQGYQLLATRL-CQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 70.5 bits (165), Expect = 2e-11
Identities = 45/118 (38%), Positives = 56/118 (47%), Gaps = 13/118 (11%)
Query: 747 DVDECAAIPGLCAPGRFRCVCG-PGYRPAGEVCADVDECAVR--PPPCDQLCHNTDGSYD 803
DV+EC IP C G +C+ GY A +++ PPP H
Sbjct: 54 DVNECLTIPEACK-GEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNP---- 108
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACV 859
C GYE D D +C DVDEC + H C+ Q C N GSY+C+C DGY K G CV
Sbjct: 109 --CPPGYEPD-DQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECV 163
Score = 49.6 bits (113), Expect = 5e-05
Identities = 35/128 (27%), Positives = 50/128 (39%), Gaps = 27/128 (21%)
Query: 535 CPYGYAVAADGVHCRDIDECVQEPRVC--PHACENVVGSYIC------------------ 574
C GY D HCRD++EC+ P C C N G Y+C
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPP 98
Query: 575 KCPEGYRRTSAP----QDSENACEDINECEEQ-EDLCSGGVCINTDGSFLCDCDAGFEPS 629
P P D +++C D++EC + D C N GS+ C C G+
Sbjct: 99 PVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR-- 156
Query: 630 EDGTDCID 637
+ G +C+D
Sbjct: 157 KIGPECVD 164
Score = 39.5 bits (88), Expect = 0.050
Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC 845
C GYE D D +CRDV+EC C + C N G Y C
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC 80
Score = 34.7 bits (76), Expect = 1.4
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 5/47 (10%)
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLC 620
+C +GY DS++ C D+NEC + C G + CIN G +LC
Sbjct: 38 ECTDGYEWDP---DSQH-CRDVNECLTIPEACKGEMKCINHYGGYLC 80
>AJ132819-1|CAA10791.2| 443|Homo sapiens fibulin-4 protein.
Length = 443
Score = 171 bits (416), Expect = 9e-42
Identities = 93/212 (43%), Positives = 117/212 (55%), Gaps = 17/212 (8%)
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICD---HGDCRNTIGSYRCECKPGYTLRENVCRDVD 193
CPPGY D C DVDEC Q + D DC N GSY+C C GY C D+D
Sbjct: 109 CPPGYE-PDDQDSCVDVDECA-QALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDID 166
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTV 252
EC R R C++ C NLPG++ C C+ GF+ GPNN CVDVNEC + G C RC N+
Sbjct: 167 EC-RYR-YCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSY 221
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
G+F C C GY L DG +C D+DEC + C C N G + C C G++L+
Sbjct: 222 GTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC----QYRCVNEPGRFSCHCPQGYQLLA 277
Query: 313 RR-CVDRDECKELPYVCAGGE-CRNFNGGYVC 342
R C D DEC+ + C+ + C NF+GGY C
Sbjct: 278 TRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 161 bits (391), Expect = 1e-38
Identities = 85/207 (41%), Positives = 109/207 (52%), Gaps = 15/207 (7%)
Query: 426 DLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTC 484
D+DEC C + C N GS++C CPDGY G CVD DEC R C + C
Sbjct: 123 DVDECAQALHDCRPSQDCHNLPGSYQCTCPDGY--RKIGPECVDIDECRY--RYCQH-RC 177
Query: 485 SNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAA 543
N G + CQC PGF GP+ ++CVDV+EC G A C RC N+ G+F C C GY +
Sbjct: 178 VNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMG-APCEQRCFNSYGTFLCRCHQGYELHR 236
Query: 544 DGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQE 603
DG C DIDEC +C + C N G + C CP+GY+ + C+DI+ECE
Sbjct: 237 DGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLAT-----RLCQDIDECESGA 291
Query: 604 DLCS-GGVCINTDGSFLC-DCDAGFEP 628
CS C+N G + C D + EP
Sbjct: 292 HQCSEAQTCVNFHGGYRCVDTNRCVEP 318
Score = 155 bits (377), Expect = 5e-37
Identities = 105/288 (36%), Positives = 141/288 (48%), Gaps = 33/288 (11%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GYE D S CRDV+EC C+G +C+N G + C L S D+
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC-------LPRSAAVINDL 91
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLRE-NVCRDVDECSRPRPVCR-NGTCENLP 211
G N C PGY + + C DVDEC++ CR + C NLP
Sbjct: 92 HGEGPPPPVPPAQHPNP-------CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLP 144
Query: 212 GAYLCHCDDGF-KAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G+Y C C DG+ K GP +CVD++ECR C++ RC N GSFRC+C PG+ L + R
Sbjct: 145 GSYQCTCPDGYRKIGP--ECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLGPNNR 199
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVC 328
+C DV+ECD + PC C N+ G + C C G++L G C D DEC Y+C
Sbjct: 200 SCVDVNECD-MGAPC----EQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC 254
Query: 329 AGGECRNFNGGYVCECPAGWRFDKTAAVC--VDERKELCYDEWEAGRC 374
C N G + C CP G++ T +C +DE + + EA C
Sbjct: 255 Q-YRCVNEPGRFSCHCPQGYQLLAT-RLCQDIDECESGAHQCSEAQTC 300
Score = 147 bits (355), Expect = 2e-34
Identities = 84/244 (34%), Positives = 116/244 (47%), Gaps = 20/244 (8%)
Query: 36 EACPPRGSPA-HTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCG 93
E PP PA H C P Y + +DEC C+P CH+ P +QC
Sbjct: 94 EGPPPPVPPAQHPNPC---PPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCT 150
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GY C D+DEC + C+ +CVNLPG+F C+C PG++L P+ C DV
Sbjct: 151 CPDGYRKIGPE--CVDIDECRYRY--CQH--RCVNLPGSFRCQCEPGFQLGPNNRSCVDV 204
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLP 211
+EC C+ C N+ G++ C C GY L + C D+DECS +C+ C N P
Sbjct: 205 NECDMGAPCEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-RCVNEP 262
Query: 212 GAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRC----ECAPGYTLT 266
G + CHC G++ C D++EC G C + C N G +RC C Y
Sbjct: 263 GRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQV 322
Query: 267 ADGR 270
++ R
Sbjct: 323 SENR 326
Score = 122 bits (295), Expect = 4e-27
Identities = 67/177 (37%), Positives = 89/177 (50%), Gaps = 13/177 (7%)
Query: 453 CPDGYVLAPDGLSCVDADECALDPRIC-GNGTCSNTRGGYECQCSPGFTQ-GPDQTCVDV 510
CP GY D SCVD DECA C + C N G Y+C C G+ + GP+ CVD+
Sbjct: 109 CPPGYE-PDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE--CVDI 165
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG 570
DEC C RC N GSFRC C G+ + + C D++EC C C N G
Sbjct: 166 DECR--YRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQRCFNSYG 222
Query: 571 SYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
+++C+C +GY +D +C DI+EC LC C+N G F C C G++
Sbjct: 223 TFLCRCHQGY---ELHRDG-FSCSDIDECSYSSYLCQYR-CVNEPGRFSCHCPQGYQ 274
Score = 118 bits (283), Expect = 1e-25
Identities = 74/216 (34%), Positives = 102/216 (47%), Gaps = 28/216 (12%)
Query: 425 QDLDECRVRPDVCVGG-RCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT 483
+D++EC P+ C G +C+N G GY+ P + ++ P
Sbjct: 53 RDVNECLTIPEACKGEMKCINHYG--------GYLCLPRSAAVINDLHGEGPPPPVPPAQ 104
Query: 484 CSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASC--TFRCHNTAGSFRCTCPYGYAV 541
N C PG+ +CVDVDECA+ C + CHN GS++CTCP GY
Sbjct: 105 HPNP-------CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK 157
Query: 542 AADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEE 601
G C DIDEC R C H C N+ GS+ C+C G++ P + +C D+NEC+
Sbjct: 158 I--GPECVDIDEC--RYRYCQHRCVNLPGSFRCQCEPGFQL--GPNN--RSCVDVNECDM 209
Query: 602 QEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C C N+ G+FLC C G+E DG C D
Sbjct: 210 GAP-CEQR-CFNSYGTFLCRCHQGYELHRDGFSCSD 243
Score = 107 bits (257), Expect = 2e-22
Identities = 89/291 (30%), Positives = 121/291 (41%), Gaps = 34/291 (11%)
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVD 317
EC GY D ++CRDV+EC +P C G C N GGY C L V
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEAC--KGEMKCINHYGGYLC-------LPRSAAVI 88
Query: 318 RDECKELPYVCAGGECRNFNGGYVCECPAGWR-FDKTAAVCVDERKELCYDEWEAGRCHR 376
D E P ++ N CP G+ D+ + V VDE + +D + CH
Sbjct: 89 NDLHGEGPPPPV-PPAQHPN-----PCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHN 142
Query: 377 ---------ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG--MGRPNLT- 424
+ PEC + + RYC+ F C+ G +G N +
Sbjct: 143 LPGSYQCTCPDGYRKIGPECVDIDECRY-RYCQHRCVNLPGSFRCQCEPGFQLGPNNRSC 201
Query: 425 QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTC 484
D++EC + C RC N+ G+F C C GY L DG SC D DEC+ +C C
Sbjct: 202 VDVNECDMGAP-C-EQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC-QYRC 258
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCT--FRCHNTAGSFRC 533
N G + C C G+ + C D+DEC G C+ C N G +RC
Sbjct: 259 VNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 104 bits (249), Expect = 2e-21
Identities = 47/112 (41%), Positives = 62/112 (55%), Gaps = 7/112 (6%)
Query: 747 DVDECAA--IPGLCA--PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTDG 800
D+DEC C PG FRC C PG++ P C DV+EC + P C+Q C N+ G
Sbjct: 164 DIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP-CEQRCFNSYG 222
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
++ C C GYEL DG +C D+DEC ++ CQ C N G + C C GY+
Sbjct: 223 TFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQ 274
Score = 95.9 bits (228), Expect = 5e-19
Identities = 47/122 (38%), Positives = 61/122 (50%), Gaps = 11/122 (9%)
Query: 743 DVFADVDECAAIPGLCAP--------GRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL 794
D DVDECA C P G ++C C GYR G C D+DEC R C
Sbjct: 119 DSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYR--YCQHR 176
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
C N GS+ C C G++L + +C DV+EC+ C+Q C N+ G++ C C GYE
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGA-PCEQRCFNSYGTFLCRCHQGYELH 235
Query: 855 GD 856
D
Sbjct: 236 RD 237
Score = 71.3 bits (167), Expect = 1e-11
Identities = 41/108 (37%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query: 747 DVDEC---AAIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTD 799
DV+EC A C + G F C C GY G C+D+DEC+ C C N
Sbjct: 203 DVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEP 262
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC 845
G + C C GY+L C+D+DECE H C Q C N G Y C
Sbjct: 263 GRFSCHCPQGYQLLATRL-CQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 70.5 bits (165), Expect = 2e-11
Identities = 45/118 (38%), Positives = 56/118 (47%), Gaps = 13/118 (11%)
Query: 747 DVDECAAIPGLCAPGRFRCVCG-PGYRPAGEVCADVDECAVR--PPPCDQLCHNTDGSYD 803
DV+EC IP C G +C+ GY A +++ PPP H
Sbjct: 54 DVNECLTIPEACK-GEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNP---- 108
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACV 859
C GYE D D +C DVDEC + H C+ Q C N GSY+C+C DGY K G CV
Sbjct: 109 --CPPGYEPD-DQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECV 163
Score = 49.6 bits (113), Expect = 5e-05
Identities = 35/128 (27%), Positives = 50/128 (39%), Gaps = 27/128 (21%)
Query: 535 CPYGYAVAADGVHCRDIDECVQEPRVC--PHACENVVGSYIC------------------ 574
C GY D HCRD++EC+ P C C N G Y+C
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPP 98
Query: 575 KCPEGYRRTSAP----QDSENACEDINECEEQ-EDLCSGGVCINTDGSFLCDCDAGFEPS 629
P P D +++C D++EC + D C N GS+ C C G+
Sbjct: 99 PVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR-- 156
Query: 630 EDGTDCID 637
+ G +C+D
Sbjct: 157 KIGPECVD 164
Score = 39.5 bits (88), Expect = 0.050
Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC 845
C GYE D D +CRDV+EC C + C N G Y C
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC 80
Score = 34.7 bits (76), Expect = 1.4
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 5/47 (10%)
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLC 620
+C +GY DS++ C D+NEC + C G + CIN G +LC
Sbjct: 38 ECTDGYEWDP---DSQH-CRDVNECLTIPEACKGEMKCINHYGGYLC 80
>AF109121-1|AAF65188.1| 443|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 2 protein.
Length = 443
Score = 171 bits (416), Expect = 9e-42
Identities = 93/212 (43%), Positives = 117/212 (55%), Gaps = 17/212 (8%)
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICD---HGDCRNTIGSYRCECKPGYTLRENVCRDVD 193
CPPGY D C DVDEC Q + D DC N GSY+C C GY C D+D
Sbjct: 109 CPPGYE-PDDQDSCVDVDECA-QALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDID 166
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTV 252
EC R R C++ C NLPG++ C C+ GF+ GPNN CVDVNEC + G C RC N+
Sbjct: 167 EC-RYR-YCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSY 221
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
G+F C C GY L DG +C D+DEC + C C N G + C C G++L+
Sbjct: 222 GTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC----QYRCVNEPGRFSCHCPQGYQLLA 277
Query: 313 RR-CVDRDECKELPYVCAGGE-CRNFNGGYVC 342
R C D DEC+ + C+ + C NF+GGY C
Sbjct: 278 TRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 161 bits (391), Expect = 1e-38
Identities = 85/207 (41%), Positives = 109/207 (52%), Gaps = 15/207 (7%)
Query: 426 DLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTC 484
D+DEC C + C N GS++C CPDGY G CVD DEC R C + C
Sbjct: 123 DVDECAQALHDCRPSQDCHNLPGSYQCTCPDGY--RKIGPECVDIDECRY--RYCQH-RC 177
Query: 485 SNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAA 543
N G + CQC PGF GP+ ++CVDV+EC G A C RC N+ G+F C C GY +
Sbjct: 178 VNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMG-APCEQRCFNSYGTFLCRCHQGYELHR 236
Query: 544 DGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQE 603
DG C DIDEC +C + C N G + C CP+GY+ + C+DI+ECE
Sbjct: 237 DGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLAT-----RLCQDIDECESGA 291
Query: 604 DLCS-GGVCINTDGSFLC-DCDAGFEP 628
CS C+N G + C D + EP
Sbjct: 292 HQCSEAQTCVNFHGGYRCVDTNRCVEP 318
Score = 155 bits (377), Expect = 5e-37
Identities = 105/288 (36%), Positives = 141/288 (48%), Gaps = 33/288 (11%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GYE D S CRDV+EC C+G +C+N G + C L S D+
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC-------LPRSAAVINDL 91
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLRE-NVCRDVDECSRPRPVCR-NGTCENLP 211
G N C PGY + + C DVDEC++ CR + C NLP
Sbjct: 92 HGEGPPPPVPPAQHPNP-------CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLP 144
Query: 212 GAYLCHCDDGF-KAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G+Y C C DG+ K GP +CVD++ECR C++ RC N GSFRC+C PG+ L + R
Sbjct: 145 GSYQCTCPDGYRKIGP--ECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLGPNNR 199
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVC 328
+C DV+ECD + PC C N+ G + C C G++L G C D DEC Y+C
Sbjct: 200 SCVDVNECD-MGAPC----EQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC 254
Query: 329 AGGECRNFNGGYVCECPAGWRFDKTAAVC--VDERKELCYDEWEAGRC 374
C N G + C CP G++ T +C +DE + + EA C
Sbjct: 255 Q-YRCVNEPGRFSCHCPQGYQLLAT-RLCQDIDECESGAHQCSEAQTC 300
Score = 147 bits (355), Expect = 2e-34
Identities = 84/244 (34%), Positives = 116/244 (47%), Gaps = 20/244 (8%)
Query: 36 EACPPRGSPA-HTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCG 93
E PP PA H C P Y + +DEC C+P CH+ P +QC
Sbjct: 94 EGPPPPVPPAQHPNPC---PPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCT 150
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GY C D+DEC + C+ +CVNLPG+F C+C PG++L P+ C DV
Sbjct: 151 CPDGYRKIGPE--CVDIDECRYRY--CQH--RCVNLPGSFRCQCEPGFQLGPNNRSCVDV 204
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLP 211
+EC C+ C N+ G++ C C GY L + C D+DECS +C+ C N P
Sbjct: 205 NECDMGAPCEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-RCVNEP 262
Query: 212 GAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRC----ECAPGYTLT 266
G + CHC G++ C D++EC G C + C N G +RC C Y
Sbjct: 263 GRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQV 322
Query: 267 ADGR 270
++ R
Sbjct: 323 SENR 326
Score = 122 bits (295), Expect = 4e-27
Identities = 67/177 (37%), Positives = 89/177 (50%), Gaps = 13/177 (7%)
Query: 453 CPDGYVLAPDGLSCVDADECALDPRIC-GNGTCSNTRGGYECQCSPGFTQ-GPDQTCVDV 510
CP GY D SCVD DECA C + C N G Y+C C G+ + GP+ CVD+
Sbjct: 109 CPPGYE-PDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE--CVDI 165
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG 570
DEC C RC N GSFRC C G+ + + C D++EC C C N G
Sbjct: 166 DECR--YRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQRCFNSYG 222
Query: 571 SYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
+++C+C +GY +D +C DI+EC LC C+N G F C C G++
Sbjct: 223 TFLCRCHQGY---ELHRDG-FSCSDIDECSYSSYLCQYR-CVNEPGRFSCHCPQGYQ 274
Score = 118 bits (283), Expect = 1e-25
Identities = 74/216 (34%), Positives = 102/216 (47%), Gaps = 28/216 (12%)
Query: 425 QDLDECRVRPDVCVGG-RCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT 483
+D++EC P+ C G +C+N G GY+ P + ++ P
Sbjct: 53 RDVNECLTIPEACKGEMKCINHYG--------GYLCLPRSAAVINDLHGEGPPPPVPPAQ 104
Query: 484 CSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASC--TFRCHNTAGSFRCTCPYGYAV 541
N C PG+ +CVDVDECA+ C + CHN GS++CTCP GY
Sbjct: 105 HPNP-------CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK 157
Query: 542 AADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEE 601
G C DIDEC R C H C N+ GS+ C+C G++ P + +C D+NEC+
Sbjct: 158 I--GPECVDIDEC--RYRYCQHRCVNLPGSFRCQCEPGFQL--GPNN--RSCVDVNECDM 209
Query: 602 QEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C C N+ G+FLC C G+E DG C D
Sbjct: 210 GAP-CEQR-CFNSYGTFLCRCHQGYELHRDGFSCSD 243
Score = 107 bits (257), Expect = 2e-22
Identities = 89/291 (30%), Positives = 121/291 (41%), Gaps = 34/291 (11%)
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVD 317
EC GY D ++CRDV+EC +P C G C N GGY C L V
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEAC--KGEMKCINHYGGYLC-------LPRSAAVI 88
Query: 318 RDECKELPYVCAGGECRNFNGGYVCECPAGWR-FDKTAAVCVDERKELCYDEWEAGRCHR 376
D E P ++ N CP G+ D+ + V VDE + +D + CH
Sbjct: 89 NDLHGEGPPPPV-PPAQHPN-----PCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHN 142
Query: 377 ---------ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG--MGRPNLT- 424
+ PEC + + RYC+ F C+ G +G N +
Sbjct: 143 LPGSYQCTCPDGYRKIGPECVDIDECRY-RYCQHRCVNLPGSFRCQCEPGFQLGPNNRSC 201
Query: 425 QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTC 484
D++EC + C RC N+ G+F C C GY L DG SC D DEC+ +C C
Sbjct: 202 VDVNECDMGAP-C-EQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC-QYRC 258
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCT--FRCHNTAGSFRC 533
N G + C C G+ + C D+DEC G C+ C N G +RC
Sbjct: 259 VNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 104 bits (249), Expect = 2e-21
Identities = 47/112 (41%), Positives = 62/112 (55%), Gaps = 7/112 (6%)
Query: 747 DVDECAA--IPGLCA--PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTDG 800
D+DEC C PG FRC C PG++ P C DV+EC + P C+Q C N+ G
Sbjct: 164 DIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP-CEQRCFNSYG 222
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
++ C C GYEL DG +C D+DEC ++ CQ C N G + C C GY+
Sbjct: 223 TFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQ 274
Score = 95.9 bits (228), Expect = 5e-19
Identities = 47/122 (38%), Positives = 61/122 (50%), Gaps = 11/122 (9%)
Query: 743 DVFADVDECAAIPGLCAP--------GRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL 794
D DVDECA C P G ++C C GYR G C D+DEC R C
Sbjct: 119 DSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYR--YCQHR 176
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
C N GS+ C C G++L + +C DV+EC+ C+Q C N+ G++ C C GYE
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGA-PCEQRCFNSYGTFLCRCHQGYELH 235
Query: 855 GD 856
D
Sbjct: 236 RD 237
Score = 71.3 bits (167), Expect = 1e-11
Identities = 41/108 (37%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query: 747 DVDEC---AAIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTD 799
DV+EC A C + G F C C GY G C+D+DEC+ C C N
Sbjct: 203 DVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEP 262
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC 845
G + C C GY+L C+D+DECE H C Q C N G Y C
Sbjct: 263 GRFSCHCPQGYQLLATRL-CQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 70.5 bits (165), Expect = 2e-11
Identities = 45/118 (38%), Positives = 56/118 (47%), Gaps = 13/118 (11%)
Query: 747 DVDECAAIPGLCAPGRFRCVCG-PGYRPAGEVCADVDECAVR--PPPCDQLCHNTDGSYD 803
DV+EC IP C G +C+ GY A +++ PPP H
Sbjct: 54 DVNECLTIPEACK-GEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNP---- 108
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACV 859
C GYE D D +C DVDEC + H C+ Q C N GSY+C+C DGY K G CV
Sbjct: 109 --CPPGYEPD-DQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECV 163
Score = 49.6 bits (113), Expect = 5e-05
Identities = 35/128 (27%), Positives = 50/128 (39%), Gaps = 27/128 (21%)
Query: 535 CPYGYAVAADGVHCRDIDECVQEPRVC--PHACENVVGSYIC------------------ 574
C GY D HCRD++EC+ P C C N G Y+C
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPP 98
Query: 575 KCPEGYRRTSAP----QDSENACEDINECEEQ-EDLCSGGVCINTDGSFLCDCDAGFEPS 629
P P D +++C D++EC + D C N GS+ C C G+
Sbjct: 99 PVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR-- 156
Query: 630 EDGTDCID 637
+ G +C+D
Sbjct: 157 KIGPECVD 164
Score = 39.5 bits (88), Expect = 0.050
Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC 845
C GYE D D +CRDV+EC C + C N G Y C
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC 80
Score = 34.7 bits (76), Expect = 1.4
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 5/47 (10%)
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLC 620
+C +GY DS++ C D+NEC + C G + CIN G +LC
Sbjct: 38 ECTDGYEWDP---DSQH-CRDVNECLTIPEACKGEMKCINHYGGYLC 80
>AB030655-1|BAA92880.1| 443|Homo sapiens mutant p53 binding protein
1 (MBP1) protein.
Length = 443
Score = 171 bits (416), Expect = 9e-42
Identities = 93/212 (43%), Positives = 117/212 (55%), Gaps = 17/212 (8%)
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICD---HGDCRNTIGSYRCECKPGYTLRENVCRDVD 193
CPPGY D C DVDEC Q + D DC N GSY+C C GY C D+D
Sbjct: 109 CPPGYE-PDDQDSCVDVDECA-QALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDID 166
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTV 252
EC R R C++ C NLPG++ C C+ GF+ GPNN CVDVNEC + G C RC N+
Sbjct: 167 EC-RYR-YCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSY 221
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
G+F C C GY L DG +C D+DEC + C C N G + C C G++L+
Sbjct: 222 GTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC----QYRCVNEPGRFSCHCPQGYQLLA 277
Query: 313 RR-CVDRDECKELPYVCAGGE-CRNFNGGYVC 342
R C D DEC+ + C+ + C NF+GGY C
Sbjct: 278 TRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 161 bits (391), Expect = 1e-38
Identities = 85/207 (41%), Positives = 109/207 (52%), Gaps = 15/207 (7%)
Query: 426 DLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTC 484
D+DEC C + C N GS++C CPDGY G CVD DEC R C + C
Sbjct: 123 DVDECAQALHDCRPSQDCHNLPGSYQCTCPDGY--RKIGPECVDIDECRY--RYCQH-RC 177
Query: 485 SNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAA 543
N G + CQC PGF GP+ ++CVDV+EC G A C RC N+ G+F C C GY +
Sbjct: 178 VNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMG-APCEQRCFNSYGTFLCRCHQGYELHR 236
Query: 544 DGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQE 603
DG C DIDEC +C + C N G + C CP+GY+ + C+DI+ECE
Sbjct: 237 DGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLAT-----RLCQDIDECESGA 291
Query: 604 DLCS-GGVCINTDGSFLC-DCDAGFEP 628
CS C+N G + C D + EP
Sbjct: 292 HQCSEAQTCVNFHGGYRCVDTNRCVEP 318
Score = 155 bits (377), Expect = 5e-37
Identities = 105/288 (36%), Positives = 141/288 (48%), Gaps = 33/288 (11%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GYE D S CRDV+EC C+G +C+N G + C L S D+
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC-------LPRSAAVINDL 91
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLRE-NVCRDVDECSRPRPVCR-NGTCENLP 211
G N C PGY + + C DVDEC++ CR + C NLP
Sbjct: 92 HGEGPPPPVPPAQHPNP-------CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLP 144
Query: 212 GAYLCHCDDGF-KAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G+Y C C DG+ K GP +CVD++ECR C++ RC N GSFRC+C PG+ L + R
Sbjct: 145 GSYQCTCPDGYRKIGP--ECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLGPNNR 199
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVC 328
+C DV+ECD + PC C N+ G + C C G++L G C D DEC Y+C
Sbjct: 200 SCVDVNECD-MGAPC----EQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC 254
Query: 329 AGGECRNFNGGYVCECPAGWRFDKTAAVC--VDERKELCYDEWEAGRC 374
C N G + C CP G++ T +C +DE + + EA C
Sbjct: 255 Q-YRCVNEPGRFSCHCPQGYQLLAT-RLCQDIDECESGAHQCSEAQTC 300
Score = 147 bits (355), Expect = 2e-34
Identities = 84/244 (34%), Positives = 116/244 (47%), Gaps = 20/244 (8%)
Query: 36 EACPPRGSPA-HTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCG 93
E PP PA H C P Y + +DEC C+P CH+ P +QC
Sbjct: 94 EGPPPPVPPAQHPNPC---PPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCT 150
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GY C D+DEC + C+ +CVNLPG+F C+C PG++L P+ C DV
Sbjct: 151 CPDGYRKIGPE--CVDIDECRYRY--CQH--RCVNLPGSFRCQCEPGFQLGPNNRSCVDV 204
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLP 211
+EC C+ C N+ G++ C C GY L + C D+DECS +C+ C N P
Sbjct: 205 NECDMGAPCEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-RCVNEP 262
Query: 212 GAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRC----ECAPGYTLT 266
G + CHC G++ C D++EC G C + C N G +RC C Y
Sbjct: 263 GRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQV 322
Query: 267 ADGR 270
++ R
Sbjct: 323 SENR 326
Score = 122 bits (295), Expect = 4e-27
Identities = 67/177 (37%), Positives = 89/177 (50%), Gaps = 13/177 (7%)
Query: 453 CPDGYVLAPDGLSCVDADECALDPRIC-GNGTCSNTRGGYECQCSPGFTQ-GPDQTCVDV 510
CP GY D SCVD DECA C + C N G Y+C C G+ + GP+ CVD+
Sbjct: 109 CPPGYE-PDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE--CVDI 165
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG 570
DEC C RC N GSFRC C G+ + + C D++EC C C N G
Sbjct: 166 DECR--YRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQRCFNSYG 222
Query: 571 SYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
+++C+C +GY +D +C DI+EC LC C+N G F C C G++
Sbjct: 223 TFLCRCHQGY---ELHRDG-FSCSDIDECSYSSYLCQYR-CVNEPGRFSCHCPQGYQ 274
Score = 118 bits (283), Expect = 1e-25
Identities = 74/216 (34%), Positives = 102/216 (47%), Gaps = 28/216 (12%)
Query: 425 QDLDECRVRPDVCVGG-RCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT 483
+D++EC P+ C G +C+N G GY+ P + ++ P
Sbjct: 53 RDVNECLTIPEACKGEMKCINHYG--------GYLCLPRSAAVINDLHGEGPPPPVPPAQ 104
Query: 484 CSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASC--TFRCHNTAGSFRCTCPYGYAV 541
N C PG+ +CVDVDECA+ C + CHN GS++CTCP GY
Sbjct: 105 HPNP-------CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK 157
Query: 542 AADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEE 601
G C DIDEC R C H C N+ GS+ C+C G++ P + +C D+NEC+
Sbjct: 158 I--GPECVDIDEC--RYRYCQHRCVNLPGSFRCQCEPGFQL--GPNN--RSCVDVNECDM 209
Query: 602 QEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C C N+ G+FLC C G+E DG C D
Sbjct: 210 GAP-CEQR-CFNSYGTFLCRCHQGYELHRDGFSCSD 243
Score = 107 bits (257), Expect = 2e-22
Identities = 89/291 (30%), Positives = 121/291 (41%), Gaps = 34/291 (11%)
Query: 258 ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVD 317
EC GY D ++CRDV+EC +P C G C N GGY C L V
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEAC--KGEMKCINHYGGYLC-------LPRSAAVI 88
Query: 318 RDECKELPYVCAGGECRNFNGGYVCECPAGWR-FDKTAAVCVDERKELCYDEWEAGRCHR 376
D E P ++ N CP G+ D+ + V VDE + +D + CH
Sbjct: 89 NDLHGEGPPPPV-PPAQHPN-----PCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHN 142
Query: 377 ---------ARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGG--MGRPNLT- 424
+ PEC + + RYC+ F C+ G +G N +
Sbjct: 143 LPGSYQCTCPDGYRKIGPECVDIDECRY-RYCQHRCVNLPGSFRCQCEPGFQLGPNNRSC 201
Query: 425 QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTC 484
D++EC + C RC N+ G+F C C GY L DG SC D DEC+ +C C
Sbjct: 202 VDVNECDMGAP-C-EQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC-QYRC 258
Query: 485 SNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCT--FRCHNTAGSFRC 533
N G + C C G+ + C D+DEC G C+ C N G +RC
Sbjct: 259 VNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 104 bits (249), Expect = 2e-21
Identities = 47/112 (41%), Positives = 62/112 (55%), Gaps = 7/112 (6%)
Query: 747 DVDECAA--IPGLCA--PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTDG 800
D+DEC C PG FRC C PG++ P C DV+EC + P C+Q C N+ G
Sbjct: 164 DIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP-CEQRCFNSYG 222
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
++ C C GYEL DG +C D+DEC ++ CQ C N G + C C GY+
Sbjct: 223 TFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQ 274
Score = 95.9 bits (228), Expect = 5e-19
Identities = 47/122 (38%), Positives = 61/122 (50%), Gaps = 11/122 (9%)
Query: 743 DVFADVDECAAIPGLCAP--------GRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL 794
D DVDECA C P G ++C C GYR G C D+DEC R C
Sbjct: 119 DSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYR--YCQHR 176
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
C N GS+ C C G++L + +C DV+EC+ C+Q C N+ G++ C C GYE
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGA-PCEQRCFNSYGTFLCRCHQGYELH 235
Query: 855 GD 856
D
Sbjct: 236 RD 237
Score = 71.3 bits (167), Expect = 1e-11
Identities = 41/108 (37%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query: 747 DVDEC---AAIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTD 799
DV+EC A C + G F C C GY G C+D+DEC+ C C N
Sbjct: 203 DVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEP 262
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC 845
G + C C GY+L C+D+DECE H C Q C N G Y C
Sbjct: 263 GRFSCHCPQGYQLLATRL-CQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 70.5 bits (165), Expect = 2e-11
Identities = 45/118 (38%), Positives = 56/118 (47%), Gaps = 13/118 (11%)
Query: 747 DVDECAAIPGLCAPGRFRCVCG-PGYRPAGEVCADVDECAVR--PPPCDQLCHNTDGSYD 803
DV+EC IP C G +C+ GY A +++ PPP H
Sbjct: 54 DVNECLTIPEACK-GEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNP---- 108
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACV 859
C GYE D D +C DVDEC + H C+ Q C N GSY+C+C DGY K G CV
Sbjct: 109 --CPPGYEPD-DQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECV 163
Score = 49.6 bits (113), Expect = 5e-05
Identities = 35/128 (27%), Positives = 50/128 (39%), Gaps = 27/128 (21%)
Query: 535 CPYGYAVAADGVHCRDIDECVQEPRVC--PHACENVVGSYIC------------------ 574
C GY D HCRD++EC+ P C C N G Y+C
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPP 98
Query: 575 KCPEGYRRTSAP----QDSENACEDINECEEQ-EDLCSGGVCINTDGSFLCDCDAGFEPS 629
P P D +++C D++EC + D C N GS+ C C G+
Sbjct: 99 PVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR-- 156
Query: 630 EDGTDCID 637
+ G +C+D
Sbjct: 157 KIGPECVD 164
Score = 39.5 bits (88), Expect = 0.050
Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC 845
C GYE D D +CRDV+EC C + C N G Y C
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC 80
Score = 34.7 bits (76), Expect = 1.4
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 5/47 (10%)
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLC 620
+C +GY DS++ C D+NEC + C G + CIN G +LC
Sbjct: 38 ECTDGYEWDP---DSQH-CRDVNECLTIPEACKGEMKCINHYGGYLC 80
>CR457140-1|CAG33421.1| 448|Homo sapiens FBLN5 protein.
Length = 448
Score = 169 bits (411), Expect = 4e-41
Identities = 89/213 (41%), Positives = 110/213 (51%), Gaps = 15/213 (7%)
Query: 413 ICQGG--MGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDA 469
IC+ G M N D+DEC C + C+NT+G + C C DGY L +G C+D
Sbjct: 112 ICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLL-EG-QCLDI 169
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTA 528
DEC C C+N G Y C C+PGFT D ++C DV+ECA C C NT
Sbjct: 170 DECRYG--YCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENP-CVQTCVNTY 225
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQD 588
GSF C C GY + DGVHC D+DEC +C H C N G+Y C CP GY D
Sbjct: 226 GSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGY----ILLD 281
Query: 589 SENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
+C+DINECE + C+ C N G F C
Sbjct: 282 DNRSCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 161 bits (391), Expect = 1e-38
Identities = 79/212 (37%), Positives = 113/212 (53%), Gaps = 13/212 (6%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GY+ D S+ C DVDEC+ C C+N G + C C GY L +C D+
Sbjct: 113 CRFGYQMDE-SNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEG--QCLDI 169
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLP 211
DEC C C N GSY C C PG+TL E+ C+DV+EC+ P + TC N
Sbjct: 170 DECR-YGYCQQL-CANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ--TCVNTY 225
Query: 212 GAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G+++C CD G++ + C D++EC +C++ C N G++ C C PGY L D R
Sbjct: 226 GSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNR 284
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYEC 302
+C+D++EC+ H C +C N GG++C
Sbjct: 285 SCQDINECEHRNHTCNL--QQTCYNLQGGFKC 314
Score = 158 bits (383), Expect = 9e-38
Identities = 97/272 (35%), Positives = 125/272 (45%), Gaps = 16/272 (5%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC--RCPPG 140
C +P Q C +G++ D S C D+DEC CRG CVN G + C R P
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPV 75
Query: 141 YRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE-NVCRDVDECSRPR 199
YR S S C+ GY + E N C DVDEC+
Sbjct: 76 YRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDS 135
Query: 200 PVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCE 258
C C N G Y C C DG+ C+D++ECR G C+ C N GS+ C
Sbjct: 136 HQCNPTQICINTEGGYTCSCTDGYWL-LEGQCLDIDECRYG--YCQQ-LCANVPGSYSCT 191
Query: 259 CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCV 316
C PG+TL DGR+C+DV+EC +PC + +C NT G + C C G++L G C
Sbjct: 192 CNPGFTLNEDGRSCQDVNEC-ATENPCVQ----TCVNTYGSFICRCDPGYELEEDGVHCS 246
Query: 317 DRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
D DEC ++C EC N G Y C CP G+
Sbjct: 247 DMDECSFSEFLCQ-HECVNQPGTYFCSCPPGY 277
Score = 149 bits (361), Expect = 4e-35
Identities = 85/215 (39%), Positives = 106/215 (49%), Gaps = 16/215 (7%)
Query: 137 CPPGYRLTPSLDECEDVDECG-DQRICDHGD-CRNTIGSYRCECKPGYTLRENVCRDVDE 194
C GY++ S ++C DVDEC D C+ C NT G Y C C GY L E C D+DE
Sbjct: 113 CRFGYQMDES-NQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDE 171
Query: 195 CSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVG 253
C C+ C N+PG+Y C C+ GF + C DVNEC + C NT G
Sbjct: 172 CRYG--YCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQT--CVNTYG 226
Query: 254 SFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV-- 311
SF C C PGY L DG +C D+DEC C + C N G Y CSC G+ L+
Sbjct: 227 SFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHE----CVNQPGTYFCSCPPGYILLDD 282
Query: 312 GRRCVDRDECKELPYVC-AGGECRNFNGGYVCECP 345
R C D +EC+ + C C N GG+ C P
Sbjct: 283 NRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDP 317
Score = 145 bits (351), Expect = 7e-34
Identities = 78/218 (35%), Positives = 104/218 (47%), Gaps = 17/218 (7%)
Query: 62 TNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+N+ +DEC C P C +T G+ C C GY C D+DEC +G C
Sbjct: 122 SNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYW--LLEGQCLDIDECRYGY--C 177
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
+ + C N+PG++ C C PG+ L C+DV+EC + C C NT GS+ C C P
Sbjct: 178 QQL--CANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ-TCVNTYGSFICRCDP 234
Query: 181 GYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF-KAGPNNDCVDVNECR 237
GY L E+ C D+DECS +C++ C N PG Y C C G+ N C D+NEC
Sbjct: 235 GYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINECE 293
Query: 238 EGGMVCR-NGRCRNTVGSFRC----ECAPGYTLTADGR 270
C C N G F+C C Y +D R
Sbjct: 294 HRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNR 331
Score = 140 bits (338), Expect = 3e-32
Identities = 71/186 (38%), Positives = 94/186 (50%), Gaps = 11/186 (5%)
Query: 453 CPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTCVDVD 511
C GY + + CVD DECA D C C NT GGY C C+ G+ Q C+D+D
Sbjct: 113 CRFGYQM-DESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQ-CLDID 170
Query: 512 ECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGS 571
EC G C C N GS+ CTC G+ + DG C+D++EC E C C N GS
Sbjct: 171 ECRYGY--CQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATE-NPCVQTCVNTYGS 227
Query: 572 YICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSED 631
+IC+C GY +D + C D++EC E LC C+N G++ C C G+ +D
Sbjct: 228 FICRCDPGYE---LEEDGVH-CSDMDECSFSEFLCQHE-CVNQPGTYFCSCPPGYILLDD 282
Query: 632 GTDCID 637
C D
Sbjct: 283 NRSCQD 288
Score = 116 bits (280), Expect = 3e-25
Identities = 95/338 (28%), Positives = 129/338 (38%), Gaps = 44/338 (13%)
Query: 207 CENLPGAYLCHCDDGFKAG-PNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCECAPGYT 264
C PG C +GF + C+D++ECR CR C N G + C P
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC--IPRTN 73
Query: 265 LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL-VGRRCVDRDECKE 323
G P+P + C G+++ +CVD DEC
Sbjct: 74 PVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECAT 133
Query: 324 LPYVCAGGE-CRNFNGGYVCECPAG-WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQ 381
+ C + C N GGY C C G W + C+D DE G C +
Sbjct: 134 DSHQCNPTQICINTEGGYTCSCTDGYWLLE---GQCLD------IDECRYGYCQQLCANV 184
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
C C+ G C QD++EC + CV
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSC----------------------QDVNECATE-NPCVQ-T 220
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
CVNT GSF C C GY L DG+ C D DEC+ +C + C N G Y C C PG+
Sbjct: 221 CVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYIL 279
Query: 502 GPD-QTCVDVDECAEGRASCTFR--CHNTAGSFRCTCP 536
D ++C D++EC +C + C+N G F+C P
Sbjct: 280 LDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDP 317
Score = 111 bits (267), Expect = 1e-23
Identities = 60/172 (34%), Positives = 87/172 (50%), Gaps = 15/172 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC C+ C + P + C C+ G+ + C+DV+EC+ P C + CV
Sbjct: 169 IDECRY--GYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENP-C--VQTCV 222
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECG-DQRICDHGDCRNTIGSYRCECKPGYTLRE 186
N G+F CRC PGY L C D+DEC + +C H +C N G+Y C C PGY L +
Sbjct: 223 NTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLD 281
Query: 187 N--VCRDVDECSRPRPVCR-NGTCENLPGAYLC----HCDDGFKAGPNNDCV 231
+ C+D++EC C TC NL G + C C++ + +N C+
Sbjct: 282 DNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCM 333
Score = 110 bits (265), Expect = 2e-23
Identities = 53/111 (47%), Positives = 62/111 (55%), Gaps = 7/111 (6%)
Query: 747 DVDEC--AAIPGLCA--PGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDG 800
D+DEC LCA PG + C C PG+ G C DV+ECA P C Q C NT G
Sbjct: 168 DIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENP-CVQTCVNTYG 226
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
S+ C C GYEL+EDG +C D+DEC CQ C N G+Y CSC GY
Sbjct: 227 SFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGY 277
Score = 105 bits (253), Expect = 5e-22
Identities = 98/342 (28%), Positives = 134/342 (39%), Gaps = 47/342 (13%)
Query: 123 MAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD--CRNTIGSYRCECKP 180
+A C+ PG + +C G+ L +C D+DEC GD C N G Y C +
Sbjct: 13 LALCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRT 72
Query: 181 GYTLRENVCRDVD-ECSRPRPVCRNG-TCENLPG-AYLCHCDDGFKAGPNNDCVDVNECR 237
R S P P + N P + C G++ +N CVDV+EC
Sbjct: 73 NPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECA 132
Query: 238 EGGMVCRNGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
C + C NT G + C C GY L +G+ C D+DEC C C N
Sbjct: 133 TDSHQCNPTQICINTEGGYTCSCTDGYWL-LEGQ-CLDIDECRY--GYC----QQLCANV 184
Query: 297 NGGYECSCGAGWKL--VGRRCVDRDEC-KELPYVCAGGECRNFNGGYVCECPAGWRFDKT 353
G Y C+C G+ L GR C D +EC E P V C N G ++C C G+ ++
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSCQDVNECATENPCV---QTCVNTYGSFICRCDPGYELEED 241
Query: 354 AAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRI 413
C D E + E+ L + EC G +C P + R
Sbjct: 242 GVHCSD-MDECSFSEF------------LCQHECVNQPGT---YFCSCPPGYILLDDNRS 285
Query: 414 CQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECP 454
C QD++EC R C + C N G F+C P
Sbjct: 286 C----------QDINECEHRNHTCNLQQTCYNLQGGFKCIDP 317
Score = 87.8 bits (208), Expect = 1e-16
Identities = 48/123 (39%), Positives = 63/123 (51%), Gaps = 13/123 (10%)
Query: 747 DVDECAA---IPGLCAP--GRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTD 799
DV+ECA C G F C C PGY G C+D+DEC+ C C N
Sbjct: 207 DVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQP 266
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC----SCEDGYEK 853
G+Y C C GY L +D +C+D++ECE HTC QQ C N +G ++C CE+ Y +
Sbjct: 267 GTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLR 326
Query: 854 RGD 856
D
Sbjct: 327 ISD 329
Score = 82.2 bits (194), Expect = 7e-15
Identities = 46/112 (41%), Positives = 56/112 (50%), Gaps = 11/112 (9%)
Query: 752 AAIPGLCAPG----RFRCVCGPGYR-PAGEVCADVDECAVRPPPCD--QLCHNTDGSYDC 804
AA P L AP +C GY+ C DVDECA C+ Q+C NT+G Y C
Sbjct: 94 AAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTC 153
Query: 805 LCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C GY L E C D+DEC CQQ+C+N GSY C+C G+ D
Sbjct: 154 SCTDGYWLLE--GQCLDIDECRYGY--CQQLCANVPGSYSCTCNPGFTLNED 201
Score = 44.4 bits (100), Expect = 0.002
Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC 845
LC + G+ C G++LD C D+DEC C+ +C N G Y C
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC 68
Score = 41.9 bits (94), Expect = 0.009
Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 6/57 (10%)
Query: 757 LCAPGRFRCVCGPGY---RPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRT 808
L +PG + C G+ R +G+ C D+DEC P C D +C N +G Y C+ RT
Sbjct: 17 LPSPGNAQAQCTNGFDLDRQSGQ-CLDIDECRTIPEACRGDMMCVNQNGGYLCIPRT 72
Score = 35.5 bits (78), Expect = 0.81
Identities = 17/53 (32%), Positives = 23/53 (43%), Gaps = 2/53 (3%)
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC--PHACENVVGSYIC 574
C + G+ + C G+ + C DIDEC P C C N G Y+C
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC 68
Score = 32.3 bits (70), Expect = 7.5
Identities = 12/29 (41%), Positives = 18/29 (62%), Gaps = 1/29 (3%)
Query: 593 CEDINECEEQEDLCSGG-VCINTDGSFLC 620
C DI+EC + C G +C+N +G +LC
Sbjct: 40 CLDIDECRTIPEACRGDMMCVNQNGGYLC 68
>BC022280-1|AAH22280.1| 448|Homo sapiens fibulin 5 protein.
Length = 448
Score = 169 bits (411), Expect = 4e-41
Identities = 89/213 (41%), Positives = 110/213 (51%), Gaps = 15/213 (7%)
Query: 413 ICQGG--MGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDA 469
IC+ G M N D+DEC C + C+NT+G + C C DGY L +G C+D
Sbjct: 112 ICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLL-EG-QCLDI 169
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTA 528
DEC C C+N G Y C C+PGFT D ++C DV+ECA C C NT
Sbjct: 170 DECRYG--YCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENP-CVQTCVNTY 225
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQD 588
GSF C C GY + DGVHC D+DEC +C H C N G+Y C CP GY D
Sbjct: 226 GSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGY----ILLD 281
Query: 589 SENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
+C+DINECE + C+ C N G F C
Sbjct: 282 DNRSCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 161 bits (391), Expect = 1e-38
Identities = 79/212 (37%), Positives = 113/212 (53%), Gaps = 13/212 (6%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GY+ D S+ C DVDEC+ C C+N G + C C GY L +C D+
Sbjct: 113 CRFGYQMDE-SNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEG--QCLDI 169
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLP 211
DEC C C N GSY C C PG+TL E+ C+DV+EC+ P + TC N
Sbjct: 170 DECR-YGYCQQL-CANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ--TCVNTY 225
Query: 212 GAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G+++C CD G++ + C D++EC +C++ C N G++ C C PGY L D R
Sbjct: 226 GSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNR 284
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYEC 302
+C+D++EC+ H C +C N GG++C
Sbjct: 285 SCQDINECEHRNHTCNL--QQTCYNLQGGFKC 314
Score = 158 bits (383), Expect = 9e-38
Identities = 97/272 (35%), Positives = 125/272 (45%), Gaps = 16/272 (5%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC--RCPPG 140
C +P Q C +G++ D S C D+DEC CRG CVN G + C R P
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPV 75
Query: 141 YRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE-NVCRDVDECSRPR 199
YR S S C+ GY + E N C DVDEC+
Sbjct: 76 YRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDS 135
Query: 200 PVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCE 258
C C N G Y C C DG+ C+D++ECR G C+ C N GS+ C
Sbjct: 136 HQCNPTQICINTEGGYTCSCTDGYWL-LEGQCLDIDECRYG--YCQQ-LCANVPGSYSCT 191
Query: 259 CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCV 316
C PG+TL DGR+C+DV+EC +PC + +C NT G + C C G++L G C
Sbjct: 192 CNPGFTLNEDGRSCQDVNEC-ATENPCVQ----TCVNTYGSFICRCDPGYELEEDGVHCS 246
Query: 317 DRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
D DEC ++C EC N G Y C CP G+
Sbjct: 247 DMDECSFSEFLCQ-HECVNQPGTYFCSCPPGY 277
Score = 149 bits (361), Expect = 4e-35
Identities = 85/215 (39%), Positives = 106/215 (49%), Gaps = 16/215 (7%)
Query: 137 CPPGYRLTPSLDECEDVDECG-DQRICDHGD-CRNTIGSYRCECKPGYTLRENVCRDVDE 194
C GY++ S ++C DVDEC D C+ C NT G Y C C GY L E C D+DE
Sbjct: 113 CRFGYQMDES-NQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDE 171
Query: 195 CSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVG 253
C C+ C N+PG+Y C C+ GF + C DVNEC + C NT G
Sbjct: 172 CRYG--YCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQT--CVNTYG 226
Query: 254 SFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV-- 311
SF C C PGY L DG +C D+DEC C + C N G Y CSC G+ L+
Sbjct: 227 SFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHE----CVNQPGTYFCSCPPGYILLDD 282
Query: 312 GRRCVDRDECKELPYVC-AGGECRNFNGGYVCECP 345
R C D +EC+ + C C N GG+ C P
Sbjct: 283 NRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDP 317
Score = 145 bits (351), Expect = 7e-34
Identities = 78/218 (35%), Positives = 104/218 (47%), Gaps = 17/218 (7%)
Query: 62 TNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+N+ +DEC C P C +T G+ C C GY C D+DEC +G C
Sbjct: 122 SNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYW--LLEGQCLDIDECRYGY--C 177
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
+ + C N+PG++ C C PG+ L C+DV+EC + C C NT GS+ C C P
Sbjct: 178 QQL--CANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ-TCVNTYGSFICRCDP 234
Query: 181 GYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF-KAGPNNDCVDVNECR 237
GY L E+ C D+DECS +C++ C N PG Y C C G+ N C D+NEC
Sbjct: 235 GYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINECE 293
Query: 238 EGGMVCR-NGRCRNTVGSFRC----ECAPGYTLTADGR 270
C C N G F+C C Y +D R
Sbjct: 294 HRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNR 331
Score = 140 bits (338), Expect = 3e-32
Identities = 71/186 (38%), Positives = 94/186 (50%), Gaps = 11/186 (5%)
Query: 453 CPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTCVDVD 511
C GY + + CVD DECA D C C NT GGY C C+ G+ Q C+D+D
Sbjct: 113 CRFGYQM-DESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQ-CLDID 170
Query: 512 ECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGS 571
EC G C C N GS+ CTC G+ + DG C+D++EC E C C N GS
Sbjct: 171 ECRYGY--CQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATE-NPCVQTCVNTYGS 227
Query: 572 YICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSED 631
+IC+C GY +D + C D++EC E LC C+N G++ C C G+ +D
Sbjct: 228 FICRCDPGYE---LEEDGVH-CSDMDECSFSEFLCQHE-CVNQPGTYFCSCPPGYILLDD 282
Query: 632 GTDCID 637
C D
Sbjct: 283 NRSCQD 288
Score = 116 bits (280), Expect = 3e-25
Identities = 95/338 (28%), Positives = 129/338 (38%), Gaps = 44/338 (13%)
Query: 207 CENLPGAYLCHCDDGFKAG-PNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCECAPGYT 264
C PG C +GF + C+D++ECR CR C N G + C P
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC--IPRTN 73
Query: 265 LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL-VGRRCVDRDECKE 323
G P+P + C G+++ +CVD DEC
Sbjct: 74 PVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECAT 133
Query: 324 LPYVCAGGE-CRNFNGGYVCECPAG-WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQ 381
+ C + C N GGY C C G W + C+D DE G C +
Sbjct: 134 DSHQCNPTQICINTEGGYTCSCTDGYWLLE---GQCLD------IDECRYGYCQQLCANV 184
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
C C+ G C QD++EC + CV
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSC----------------------QDVNECATE-NPCVQ-T 220
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
CVNT GSF C C GY L DG+ C D DEC+ +C + C N G Y C C PG+
Sbjct: 221 CVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYIL 279
Query: 502 GPD-QTCVDVDECAEGRASCTFR--CHNTAGSFRCTCP 536
D ++C D++EC +C + C+N G F+C P
Sbjct: 280 LDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDP 317
Score = 111 bits (267), Expect = 1e-23
Identities = 60/172 (34%), Positives = 87/172 (50%), Gaps = 15/172 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC C+ C + P + C C+ G+ + C+DV+EC+ P C + CV
Sbjct: 169 IDECRY--GYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENP-C--VQTCV 222
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECG-DQRICDHGDCRNTIGSYRCECKPGYTLRE 186
N G+F CRC PGY L C D+DEC + +C H +C N G+Y C C PGY L +
Sbjct: 223 NTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLD 281
Query: 187 N--VCRDVDECSRPRPVCR-NGTCENLPGAYLC----HCDDGFKAGPNNDCV 231
+ C+D++EC C TC NL G + C C++ + +N C+
Sbjct: 282 DNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCM 333
Score = 110 bits (265), Expect = 2e-23
Identities = 53/111 (47%), Positives = 62/111 (55%), Gaps = 7/111 (6%)
Query: 747 DVDEC--AAIPGLCA--PGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDG 800
D+DEC LCA PG + C C PG+ G C DV+ECA P C Q C NT G
Sbjct: 168 DIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENP-CVQTCVNTYG 226
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
S+ C C GYEL+EDG +C D+DEC CQ C N G+Y CSC GY
Sbjct: 227 SFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGY 277
Score = 105 bits (253), Expect = 5e-22
Identities = 98/342 (28%), Positives = 134/342 (39%), Gaps = 47/342 (13%)
Query: 123 MAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD--CRNTIGSYRCECKP 180
+A C+ PG + +C G+ L +C D+DEC GD C N G Y C +
Sbjct: 13 LALCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRT 72
Query: 181 GYTLRENVCRDVD-ECSRPRPVCRNG-TCENLPG-AYLCHCDDGFKAGPNNDCVDVNECR 237
R S P P + N P + C G++ +N CVDV+EC
Sbjct: 73 NPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECA 132
Query: 238 EGGMVCRNGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
C + C NT G + C C GY L +G+ C D+DEC C C N
Sbjct: 133 TDSHQCNPTQICINTEGGYTCSCTDGYWL-LEGQ-CLDIDECRY--GYC----QQLCANV 184
Query: 297 NGGYECSCGAGWKL--VGRRCVDRDEC-KELPYVCAGGECRNFNGGYVCECPAGWRFDKT 353
G Y C+C G+ L GR C D +EC E P V C N G ++C C G+ ++
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSCQDVNECATENPCV---QTCVNTYGSFICRCDPGYELEED 241
Query: 354 AAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRI 413
C D E + E+ L + EC G +C P + R
Sbjct: 242 GVHCSD-MDECSFSEF------------LCQHECVNQPGT---YFCSCPPGYILLDDNRS 285
Query: 414 CQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECP 454
C QD++EC R C + C N G F+C P
Sbjct: 286 C----------QDINECEHRNHTCNLQQTCYNLQGGFKCIDP 317
Score = 87.8 bits (208), Expect = 1e-16
Identities = 48/123 (39%), Positives = 63/123 (51%), Gaps = 13/123 (10%)
Query: 747 DVDECAA---IPGLCAP--GRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTD 799
DV+ECA C G F C C PGY G C+D+DEC+ C C N
Sbjct: 207 DVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQP 266
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC----SCEDGYEK 853
G+Y C C GY L +D +C+D++ECE HTC QQ C N +G ++C CE+ Y +
Sbjct: 267 GTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLR 326
Query: 854 RGD 856
D
Sbjct: 327 ISD 329
Score = 82.2 bits (194), Expect = 7e-15
Identities = 46/112 (41%), Positives = 56/112 (50%), Gaps = 11/112 (9%)
Query: 752 AAIPGLCAPG----RFRCVCGPGYR-PAGEVCADVDECAVRPPPCD--QLCHNTDGSYDC 804
AA P L AP +C GY+ C DVDECA C+ Q+C NT+G Y C
Sbjct: 94 AAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTC 153
Query: 805 LCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C GY L E C D+DEC CQQ+C+N GSY C+C G+ D
Sbjct: 154 SCTDGYWLLE--GQCLDIDECRYGY--CQQLCANVPGSYSCTCNPGFTLNED 201
Score = 44.4 bits (100), Expect = 0.002
Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC 845
LC + G+ C G++LD C D+DEC C+ +C N G Y C
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC 68
Score = 41.9 bits (94), Expect = 0.009
Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 6/57 (10%)
Query: 757 LCAPGRFRCVCGPGY---RPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRT 808
L +PG + C G+ R +G+ C D+DEC P C D +C N +G Y C+ RT
Sbjct: 17 LPSPGNAQAQCTNGFDLDRQSGQ-CLDIDECRTIPEACRGDMMCVNQNGGYLCIPRT 72
Score = 35.5 bits (78), Expect = 0.81
Identities = 17/53 (32%), Positives = 23/53 (43%), Gaps = 2/53 (3%)
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC--PHACENVVGSYIC 574
C + G+ + C G+ + C DIDEC P C C N G Y+C
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC 68
Score = 32.3 bits (70), Expect = 7.5
Identities = 12/29 (41%), Positives = 18/29 (62%), Gaps = 1/29 (3%)
Query: 593 CEDINECEEQEDLCSGG-VCINTDGSFLC 620
C DI+EC + C G +C+N +G +LC
Sbjct: 40 CLDIDECRTIPEACRGDMMCVNQNGGYLC 68
>AJ133490-1|CAB38568.1| 448|Homo sapiens fibulin-5 protein.
Length = 448
Score = 169 bits (411), Expect = 4e-41
Identities = 89/213 (41%), Positives = 110/213 (51%), Gaps = 15/213 (7%)
Query: 413 ICQGG--MGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDA 469
IC+ G M N D+DEC C + C+NT+G + C C DGY L +G C+D
Sbjct: 112 ICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLL-EG-QCLDI 169
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTA 528
DEC C C+N G Y C C+PGFT D ++C DV+ECA C C NT
Sbjct: 170 DECRYG--YCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENP-CVQTCVNTY 225
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQD 588
GSF C C GY + DGVHC D+DEC +C H C N G+Y C CP GY D
Sbjct: 226 GSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGY----ILLD 281
Query: 589 SENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
+C+DINECE + C+ C N G F C
Sbjct: 282 DNRSCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 161 bits (391), Expect = 1e-38
Identities = 79/212 (37%), Positives = 113/212 (53%), Gaps = 13/212 (6%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GY+ D S+ C DVDEC+ C C+N G + C C GY L +C D+
Sbjct: 113 CRFGYQMDE-SNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEG--QCLDI 169
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLP 211
DEC C C N GSY C C PG+TL E+ C+DV+EC+ P + TC N
Sbjct: 170 DECR-YGYCQQL-CANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ--TCVNTY 225
Query: 212 GAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G+++C CD G++ + C D++EC +C++ C N G++ C C PGY L D R
Sbjct: 226 GSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNR 284
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYEC 302
+C+D++EC+ H C +C N GG++C
Sbjct: 285 SCQDINECEHRNHTCNL--QQTCYNLQGGFKC 314
Score = 158 bits (383), Expect = 9e-38
Identities = 97/272 (35%), Positives = 125/272 (45%), Gaps = 16/272 (5%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC--RCPPG 140
C +P Q C +G++ D S C D+DEC CRG CVN G + C R P
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPV 75
Query: 141 YRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE-NVCRDVDECSRPR 199
YR S S C+ GY + E N C DVDEC+
Sbjct: 76 YRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDS 135
Query: 200 PVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCE 258
C C N G Y C C DG+ C+D++ECR G C+ C N GS+ C
Sbjct: 136 HQCNPTQICINTEGGYTCSCTDGYWL-LEGQCLDIDECRYG--YCQQ-LCANVPGSYSCT 191
Query: 259 CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCV 316
C PG+TL DGR+C+DV+EC +PC + +C NT G + C C G++L G C
Sbjct: 192 CNPGFTLNEDGRSCQDVNEC-ATENPCVQ----TCVNTYGSFICRCDPGYELEEDGVHCS 246
Query: 317 DRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
D DEC ++C EC N G Y C CP G+
Sbjct: 247 DMDECSFSEFLCQ-HECVNQPGTYFCSCPPGY 277
Score = 149 bits (361), Expect = 4e-35
Identities = 85/215 (39%), Positives = 106/215 (49%), Gaps = 16/215 (7%)
Query: 137 CPPGYRLTPSLDECEDVDECG-DQRICDHGD-CRNTIGSYRCECKPGYTLRENVCRDVDE 194
C GY++ S ++C DVDEC D C+ C NT G Y C C GY L E C D+DE
Sbjct: 113 CRFGYQMDES-NQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDE 171
Query: 195 CSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVG 253
C C+ C N+PG+Y C C+ GF + C DVNEC + C NT G
Sbjct: 172 CRYG--YCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQT--CVNTYG 226
Query: 254 SFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV-- 311
SF C C PGY L DG +C D+DEC C + C N G Y CSC G+ L+
Sbjct: 227 SFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHE----CVNQPGTYFCSCPPGYILLDD 282
Query: 312 GRRCVDRDECKELPYVC-AGGECRNFNGGYVCECP 345
R C D +EC+ + C C N GG+ C P
Sbjct: 283 NRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDP 317
Score = 145 bits (351), Expect = 7e-34
Identities = 78/218 (35%), Positives = 104/218 (47%), Gaps = 17/218 (7%)
Query: 62 TNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+N+ +DEC C P C +T G+ C C GY C D+DEC +G C
Sbjct: 122 SNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYW--LLEGQCLDIDECRYGY--C 177
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
+ + C N+PG++ C C PG+ L C+DV+EC + C C NT GS+ C C P
Sbjct: 178 QQL--CANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ-TCVNTYGSFICRCDP 234
Query: 181 GYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF-KAGPNNDCVDVNECR 237
GY L E+ C D+DECS +C++ C N PG Y C C G+ N C D+NEC
Sbjct: 235 GYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINECE 293
Query: 238 EGGMVCR-NGRCRNTVGSFRC----ECAPGYTLTADGR 270
C C N G F+C C Y +D R
Sbjct: 294 HRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNR 331
Score = 140 bits (338), Expect = 3e-32
Identities = 71/186 (38%), Positives = 94/186 (50%), Gaps = 11/186 (5%)
Query: 453 CPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTCVDVD 511
C GY + + CVD DECA D C C NT GGY C C+ G+ Q C+D+D
Sbjct: 113 CRFGYQM-DESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQ-CLDID 170
Query: 512 ECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGS 571
EC G C C N GS+ CTC G+ + DG C+D++EC E C C N GS
Sbjct: 171 ECRYGY--CQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATE-NPCVQTCVNTYGS 227
Query: 572 YICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSED 631
+IC+C GY +D + C D++EC E LC C+N G++ C C G+ +D
Sbjct: 228 FICRCDPGYE---LEEDGVH-CSDMDECSFSEFLCQHE-CVNQPGTYFCSCPPGYILLDD 282
Query: 632 GTDCID 637
C D
Sbjct: 283 NRSCQD 288
Score = 116 bits (280), Expect = 3e-25
Identities = 95/338 (28%), Positives = 129/338 (38%), Gaps = 44/338 (13%)
Query: 207 CENLPGAYLCHCDDGFKAG-PNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCECAPGYT 264
C PG C +GF + C+D++ECR CR C N G + C P
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC--IPRTN 73
Query: 265 LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL-VGRRCVDRDECKE 323
G P+P + C G+++ +CVD DEC
Sbjct: 74 PVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECAT 133
Query: 324 LPYVCAGGE-CRNFNGGYVCECPAG-WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQ 381
+ C + C N GGY C C G W + C+D DE G C +
Sbjct: 134 DSHQCNPTQICINTEGGYTCSCTDGYWLLE---GQCLD------IDECRYGYCQQLCANV 184
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
C C+ G C QD++EC + CV
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSC----------------------QDVNECATE-NPCVQ-T 220
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
CVNT GSF C C GY L DG+ C D DEC+ +C + C N G Y C C PG+
Sbjct: 221 CVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYIL 279
Query: 502 GPD-QTCVDVDECAEGRASCTFR--CHNTAGSFRCTCP 536
D ++C D++EC +C + C+N G F+C P
Sbjct: 280 LDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDP 317
Score = 111 bits (267), Expect = 1e-23
Identities = 60/172 (34%), Positives = 87/172 (50%), Gaps = 15/172 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC C+ C + P + C C+ G+ + C+DV+EC+ P C + CV
Sbjct: 169 IDECRY--GYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENP-C--VQTCV 222
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECG-DQRICDHGDCRNTIGSYRCECKPGYTLRE 186
N G+F CRC PGY L C D+DEC + +C H +C N G+Y C C PGY L +
Sbjct: 223 NTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLD 281
Query: 187 N--VCRDVDECSRPRPVCR-NGTCENLPGAYLC----HCDDGFKAGPNNDCV 231
+ C+D++EC C TC NL G + C C++ + +N C+
Sbjct: 282 DNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCM 333
Score = 110 bits (265), Expect = 2e-23
Identities = 53/111 (47%), Positives = 62/111 (55%), Gaps = 7/111 (6%)
Query: 747 DVDEC--AAIPGLCA--PGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDG 800
D+DEC LCA PG + C C PG+ G C DV+ECA P C Q C NT G
Sbjct: 168 DIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENP-CVQTCVNTYG 226
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
S+ C C GYEL+EDG +C D+DEC CQ C N G+Y CSC GY
Sbjct: 227 SFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGY 277
Score = 105 bits (253), Expect = 5e-22
Identities = 98/342 (28%), Positives = 134/342 (39%), Gaps = 47/342 (13%)
Query: 123 MAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD--CRNTIGSYRCECKP 180
+A C+ PG + +C G+ L +C D+DEC GD C N G Y C +
Sbjct: 13 LALCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRT 72
Query: 181 GYTLRENVCRDVD-ECSRPRPVCRNG-TCENLPG-AYLCHCDDGFKAGPNNDCVDVNECR 237
R S P P + N P + C G++ +N CVDV+EC
Sbjct: 73 NPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECA 132
Query: 238 EGGMVCRNGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
C + C NT G + C C GY L +G+ C D+DEC C C N
Sbjct: 133 TDSHQCNPTQICINTEGGYTCSCTDGYWL-LEGQ-CLDIDECRY--GYC----QQLCANV 184
Query: 297 NGGYECSCGAGWKL--VGRRCVDRDEC-KELPYVCAGGECRNFNGGYVCECPAGWRFDKT 353
G Y C+C G+ L GR C D +EC E P V C N G ++C C G+ ++
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSCQDVNECATENPCV---QTCVNTYGSFICRCDPGYELEED 241
Query: 354 AAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRI 413
C D E + E+ L + EC G +C P + R
Sbjct: 242 GVHCSD-MDECSFSEF------------LCQHECVNQPGT---YFCSCPPGYILLDDNRS 285
Query: 414 CQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECP 454
C QD++EC R C + C N G F+C P
Sbjct: 286 C----------QDINECEHRNHTCNLQQTCYNLQGGFKCIDP 317
Score = 87.8 bits (208), Expect = 1e-16
Identities = 48/123 (39%), Positives = 63/123 (51%), Gaps = 13/123 (10%)
Query: 747 DVDECAA---IPGLCAP--GRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTD 799
DV+ECA C G F C C PGY G C+D+DEC+ C C N
Sbjct: 207 DVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQP 266
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC----SCEDGYEK 853
G+Y C C GY L +D +C+D++ECE HTC QQ C N +G ++C CE+ Y +
Sbjct: 267 GTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLR 326
Query: 854 RGD 856
D
Sbjct: 327 ISD 329
Score = 82.2 bits (194), Expect = 7e-15
Identities = 46/112 (41%), Positives = 56/112 (50%), Gaps = 11/112 (9%)
Query: 752 AAIPGLCAPG----RFRCVCGPGYR-PAGEVCADVDECAVRPPPCD--QLCHNTDGSYDC 804
AA P L AP +C GY+ C DVDECA C+ Q+C NT+G Y C
Sbjct: 94 AAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTC 153
Query: 805 LCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C GY L E C D+DEC CQQ+C+N GSY C+C G+ D
Sbjct: 154 SCTDGYWLLE--GQCLDIDECRYGY--CQQLCANVPGSYSCTCNPGFTLNED 201
Score = 44.4 bits (100), Expect = 0.002
Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC 845
LC + G+ C G++LD C D+DEC C+ +C N G Y C
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC 68
Score = 41.9 bits (94), Expect = 0.009
Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 6/57 (10%)
Query: 757 LCAPGRFRCVCGPGY---RPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRT 808
L +PG + C G+ R +G+ C D+DEC P C D +C N +G Y C+ RT
Sbjct: 17 LPSPGNAQAQCTNGFDLDRQSGQ-CLDIDECRTIPEACRGDMMCVNQNGGYLCIPRT 72
Score = 35.5 bits (78), Expect = 0.81
Identities = 17/53 (32%), Positives = 23/53 (43%), Gaps = 2/53 (3%)
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC--PHACENVVGSYIC 574
C + G+ + C G+ + C DIDEC P C C N G Y+C
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC 68
Score = 32.3 bits (70), Expect = 7.5
Identities = 12/29 (41%), Positives = 18/29 (62%), Gaps = 1/29 (3%)
Query: 593 CEDINECEEQEDLCSGG-VCINTDGSFLC 620
C DI+EC + C G +C+N +G +LC
Sbjct: 40 CLDIDECRTIPEACRGDMMCVNQNGGYLC 68
>AF112152-1|AAD41768.1| 448|Homo sapiens developmental arteries and
neural crest EGF-like protein protein.
Length = 448
Score = 169 bits (411), Expect = 4e-41
Identities = 89/213 (41%), Positives = 110/213 (51%), Gaps = 15/213 (7%)
Query: 413 ICQGG--MGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDA 469
IC+ G M N D+DEC C + C+NT+G + C C DGY L +G C+D
Sbjct: 112 ICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLL-EG-QCLDI 169
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTA 528
DEC C C+N G Y C C+PGFT D ++C DV+ECA C C NT
Sbjct: 170 DECRYG--YCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENP-CVQTCVNTY 225
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQD 588
GSF C C GY + DGVHC D+DEC +C H C N G+Y C CP GY D
Sbjct: 226 GSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGY----ILLD 281
Query: 589 SENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
+C+DINECE + C+ C N G F C
Sbjct: 282 DNRSCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 161 bits (391), Expect = 1e-38
Identities = 79/212 (37%), Positives = 113/212 (53%), Gaps = 13/212 (6%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GY+ D S+ C DVDEC+ C C+N G + C C GY L +C D+
Sbjct: 113 CRFGYQMDE-SNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEG--QCLDI 169
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLP 211
DEC C C N GSY C C PG+TL E+ C+DV+EC+ P + TC N
Sbjct: 170 DECR-YGYCQQL-CANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ--TCVNTY 225
Query: 212 GAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G+++C CD G++ + C D++EC +C++ C N G++ C C PGY L D R
Sbjct: 226 GSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNR 284
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYEC 302
+C+D++EC+ H C +C N GG++C
Sbjct: 285 SCQDINECEHRNHTCNL--QQTCYNLQGGFKC 314
Score = 158 bits (383), Expect = 9e-38
Identities = 97/272 (35%), Positives = 125/272 (45%), Gaps = 16/272 (5%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC--RCPPG 140
C +P Q C +G++ D S C D+DEC CRG CVN G + C R P
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPV 75
Query: 141 YRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE-NVCRDVDECSRPR 199
YR S S C+ GY + E N C DVDEC+
Sbjct: 76 YRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDS 135
Query: 200 PVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCE 258
C C N G Y C C DG+ C+D++ECR G C+ C N GS+ C
Sbjct: 136 HQCNPTQICINTEGGYTCSCTDGYWL-LEGQCLDIDECRYG--YCQQ-LCANVPGSYSCT 191
Query: 259 CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCV 316
C PG+TL DGR+C+DV+EC +PC + +C NT G + C C G++L G C
Sbjct: 192 CNPGFTLNEDGRSCQDVNEC-ATENPCVQ----TCVNTYGSFICRCDPGYELEEDGVHCS 246
Query: 317 DRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
D DEC ++C EC N G Y C CP G+
Sbjct: 247 DMDECSFSEFLCQ-HECVNQPGTYFCSCPPGY 277
Score = 149 bits (361), Expect = 4e-35
Identities = 85/215 (39%), Positives = 106/215 (49%), Gaps = 16/215 (7%)
Query: 137 CPPGYRLTPSLDECEDVDECG-DQRICDHGD-CRNTIGSYRCECKPGYTLRENVCRDVDE 194
C GY++ S ++C DVDEC D C+ C NT G Y C C GY L E C D+DE
Sbjct: 113 CRFGYQMDES-NQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDE 171
Query: 195 CSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVG 253
C C+ C N+PG+Y C C+ GF + C DVNEC + C NT G
Sbjct: 172 CRYG--YCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQT--CVNTYG 226
Query: 254 SFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV-- 311
SF C C PGY L DG +C D+DEC C + C N G Y CSC G+ L+
Sbjct: 227 SFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHE----CVNQPGTYFCSCPPGYILLDD 282
Query: 312 GRRCVDRDECKELPYVC-AGGECRNFNGGYVCECP 345
R C D +EC+ + C C N GG+ C P
Sbjct: 283 NRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDP 317
Score = 145 bits (351), Expect = 7e-34
Identities = 78/218 (35%), Positives = 104/218 (47%), Gaps = 17/218 (7%)
Query: 62 TNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+N+ +DEC C P C +T G+ C C GY C D+DEC +G C
Sbjct: 122 SNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYW--LLEGQCLDIDECRYGY--C 177
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
+ + C N+PG++ C C PG+ L C+DV+EC + C C NT GS+ C C P
Sbjct: 178 QQL--CANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ-TCVNTYGSFICRCDP 234
Query: 181 GYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF-KAGPNNDCVDVNECR 237
GY L E+ C D+DECS +C++ C N PG Y C C G+ N C D+NEC
Sbjct: 235 GYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINECE 293
Query: 238 EGGMVCR-NGRCRNTVGSFRC----ECAPGYTLTADGR 270
C C N G F+C C Y +D R
Sbjct: 294 HRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNR 331
Score = 140 bits (338), Expect = 3e-32
Identities = 71/186 (38%), Positives = 94/186 (50%), Gaps = 11/186 (5%)
Query: 453 CPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTCVDVD 511
C GY + + CVD DECA D C C NT GGY C C+ G+ Q C+D+D
Sbjct: 113 CRFGYQM-DESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQ-CLDID 170
Query: 512 ECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGS 571
EC G C C N GS+ CTC G+ + DG C+D++EC E C C N GS
Sbjct: 171 ECRYGY--CQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATE-NPCVQTCVNTYGS 227
Query: 572 YICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSED 631
+IC+C GY +D + C D++EC E LC C+N G++ C C G+ +D
Sbjct: 228 FICRCDPGYE---LEEDGVH-CSDMDECSFSEFLCQHE-CVNQPGTYFCSCPPGYILLDD 282
Query: 632 GTDCID 637
C D
Sbjct: 283 NRSCQD 288
Score = 116 bits (280), Expect = 3e-25
Identities = 95/338 (28%), Positives = 129/338 (38%), Gaps = 44/338 (13%)
Query: 207 CENLPGAYLCHCDDGFKAG-PNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCECAPGYT 264
C PG C +GF + C+D++ECR CR C N G + C P
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC--IPRTN 73
Query: 265 LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL-VGRRCVDRDECKE 323
G P+P + C G+++ +CVD DEC
Sbjct: 74 PVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECAT 133
Query: 324 LPYVCAGGE-CRNFNGGYVCECPAG-WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQ 381
+ C + C N GGY C C G W + C+D DE G C +
Sbjct: 134 DSHQCNPTQICINTEGGYTCSCTDGYWLLE---GQCLD------IDECRYGYCQQLCANV 184
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
C C+ G C QD++EC + CV
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSC----------------------QDVNECATE-NPCVQ-T 220
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
CVNT GSF C C GY L DG+ C D DEC+ +C + C N G Y C C PG+
Sbjct: 221 CVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYIL 279
Query: 502 GPD-QTCVDVDECAEGRASCTFR--CHNTAGSFRCTCP 536
D ++C D++EC +C + C+N G F+C P
Sbjct: 280 LDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDP 317
Score = 111 bits (267), Expect = 1e-23
Identities = 60/172 (34%), Positives = 87/172 (50%), Gaps = 15/172 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC C+ C + P + C C+ G+ + C+DV+EC+ P C + CV
Sbjct: 169 IDECRY--GYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENP-C--VQTCV 222
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECG-DQRICDHGDCRNTIGSYRCECKPGYTLRE 186
N G+F CRC PGY L C D+DEC + +C H +C N G+Y C C PGY L +
Sbjct: 223 NTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLD 281
Query: 187 N--VCRDVDECSRPRPVCR-NGTCENLPGAYLC----HCDDGFKAGPNNDCV 231
+ C+D++EC C TC NL G + C C++ + +N C+
Sbjct: 282 DNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCM 333
Score = 110 bits (265), Expect = 2e-23
Identities = 53/111 (47%), Positives = 62/111 (55%), Gaps = 7/111 (6%)
Query: 747 DVDEC--AAIPGLCA--PGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDG 800
D+DEC LCA PG + C C PG+ G C DV+ECA P C Q C NT G
Sbjct: 168 DIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENP-CVQTCVNTYG 226
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
S+ C C GYEL+EDG +C D+DEC CQ C N G+Y CSC GY
Sbjct: 227 SFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGY 277
Score = 105 bits (253), Expect = 5e-22
Identities = 98/342 (28%), Positives = 134/342 (39%), Gaps = 47/342 (13%)
Query: 123 MAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD--CRNTIGSYRCECKP 180
+A C+ PG + +C G+ L +C D+DEC GD C N G Y C +
Sbjct: 13 LALCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRT 72
Query: 181 GYTLRENVCRDVD-ECSRPRPVCRNG-TCENLPG-AYLCHCDDGFKAGPNNDCVDVNECR 237
R S P P + N P + C G++ +N CVDV+EC
Sbjct: 73 NPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECA 132
Query: 238 EGGMVCRNGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
C + C NT G + C C GY L +G+ C D+DEC C C N
Sbjct: 133 TDSHQCNPTQICINTEGGYTCSCTDGYWL-LEGQ-CLDIDECRY--GYC----QQLCANV 184
Query: 297 NGGYECSCGAGWKL--VGRRCVDRDEC-KELPYVCAGGECRNFNGGYVCECPAGWRFDKT 353
G Y C+C G+ L GR C D +EC E P V C N G ++C C G+ ++
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSCQDVNECATENPCV---QTCVNTYGSFICRCDPGYELEED 241
Query: 354 AAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRI 413
C D E + E+ L + EC G +C P + R
Sbjct: 242 GVHCSD-MDECSFSEF------------LCQHECVNQPGT---YFCSCPPGYILLDDNRS 285
Query: 414 CQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECP 454
C QD++EC R C + C N G F+C P
Sbjct: 286 C----------QDINECEHRNHTCNLQQTCYNLQGGFKCIDP 317
Score = 87.8 bits (208), Expect = 1e-16
Identities = 48/123 (39%), Positives = 63/123 (51%), Gaps = 13/123 (10%)
Query: 747 DVDECAA---IPGLCAP--GRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTD 799
DV+ECA C G F C C PGY G C+D+DEC+ C C N
Sbjct: 207 DVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQP 266
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC----SCEDGYEK 853
G+Y C C GY L +D +C+D++ECE HTC QQ C N +G ++C CE+ Y +
Sbjct: 267 GTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLR 326
Query: 854 RGD 856
D
Sbjct: 327 ISD 329
Score = 82.2 bits (194), Expect = 7e-15
Identities = 46/112 (41%), Positives = 56/112 (50%), Gaps = 11/112 (9%)
Query: 752 AAIPGLCAPG----RFRCVCGPGYR-PAGEVCADVDECAVRPPPCD--QLCHNTDGSYDC 804
AA P L AP +C GY+ C DVDECA C+ Q+C NT+G Y C
Sbjct: 94 AAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTC 153
Query: 805 LCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C GY L E C D+DEC CQQ+C+N GSY C+C G+ D
Sbjct: 154 SCTDGYWLLE--GQCLDIDECRYGY--CQQLCANVPGSYSCTCNPGFTLNED 201
Score = 44.4 bits (100), Expect = 0.002
Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC 845
LC + G+ C G++LD C D+DEC C+ +C N G Y C
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC 68
Score = 41.9 bits (94), Expect = 0.009
Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 6/57 (10%)
Query: 757 LCAPGRFRCVCGPGY---RPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRT 808
L +PG + C G+ R +G+ C D+DEC P C D +C N +G Y C+ RT
Sbjct: 17 LPSPGNAQAQCTNGFDLDRQSGQ-CLDIDECRTIPEACRGDMMCVNQNGGYLCIPRT 72
Score = 35.5 bits (78), Expect = 0.81
Identities = 17/53 (32%), Positives = 23/53 (43%), Gaps = 2/53 (3%)
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC--PHACENVVGSYIC 574
C + G+ + C G+ + C DIDEC P C C N G Y+C
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC 68
Score = 32.3 bits (70), Expect = 7.5
Identities = 12/29 (41%), Positives = 18/29 (62%), Gaps = 1/29 (3%)
Query: 593 CEDINECEEQEDLCSGG-VCINTDGSFLC 620
C DI+EC + C G +C+N +G +LC
Sbjct: 40 CLDIDECRTIPEACRGDMMCVNQNGGYLC 68
>U03877-1|AAA65590.1| 387|Homo sapiens extracellular protein
protein.
Length = 387
Score = 169 bits (410), Expect = 5e-41
Identities = 81/201 (40%), Positives = 109/201 (54%), Gaps = 12/201 (5%)
Query: 422 NLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG 480
N+ QD+DEC C + C+N GSF C+CP GY G CVD DEC + P C
Sbjct: 63 NVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGY--QKRGEQCVDIDECTIPP-YC- 118
Query: 481 NGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGY 539
+ C NT G + CQCSPGF + TCVD++EC + C +C+N GSF C C GY
Sbjct: 119 HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQCAQQCYNILGSFICQCNQGY 177
Query: 540 AVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINEC 599
+++D ++C DIDEC +C + C N G + C CP+GY+ + C+DINEC
Sbjct: 178 ELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRS-----RTCQDINEC 232
Query: 600 EEQEDLCSGGVCINTDGSFLC 620
E + +C N G F C
Sbjct: 233 ETTNECREDEMCWNYHGGFRC 253
Score = 164 bits (398), Expect = 1e-39
Identities = 87/243 (35%), Positives = 128/243 (52%), Gaps = 22/243 (9%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GYE ++C+D+DEC+ G CR C+NL G+F C+CPPGY+ ++C D+
Sbjct: 53 CAAGYEQSE-HNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRG--EQCVDI 109
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLP 211
DEC C H C NT GS+ C+C PG+ L N C D++EC + C N+
Sbjct: 110 DECTIPPYC-HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQ--CYNIL 166
Query: 212 GAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G+++C C+ G++ + +C D++ECR +C+ +C N G F C C GY + R
Sbjct: 167 GSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGYQVVR-SR 224
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYEC----SCGAGWKLV-GRRC---VDRDECK 322
C+D++EC E + C D C N +GG+ C C + L RC V C+
Sbjct: 225 TCQDINEC-ETTNECRED--EMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCR 281
Query: 323 ELP 325
ELP
Sbjct: 282 ELP 284
Score = 140 bits (338), Expect = 3e-32
Identities = 73/186 (39%), Positives = 99/186 (53%), Gaps = 10/186 (5%)
Query: 443 VNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRIC-GNGTCSNTRGGYECQCSPGFTQ 501
+ ++ S R +C GY + + C D DEC C + C N RG + CQC PG+ +
Sbjct: 43 IPSNPSHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQK 101
Query: 502 GPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC 561
+Q CVD+DEC C RC NT GSF C C G+ +AA+ C DI+EC C
Sbjct: 102 RGEQ-CVDIDECTIP-PYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQC 158
Query: 562 PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCD 621
C N++GS+IC+C +GY +S D N CEDI+EC LC C+N G F C
Sbjct: 159 AQQCYNILGSFICQCNQGYELSS---DRLN-CEDIDECRTSSYLCQYQ-CVNEPGKFSCM 213
Query: 622 CDAGFE 627
C G++
Sbjct: 214 CPQGYQ 219
Score = 110 bits (264), Expect = 2e-23
Identities = 56/149 (37%), Positives = 72/149 (48%), Gaps = 11/149 (7%)
Query: 491 YECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHC 548
+ QC+ G+ Q C D+DEC G +C C N GSF C CP GY G C
Sbjct: 49 HRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQC 106
Query: 549 RDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSG 608
DIDEC P C C N GS+ C+C G++ + + C DINEC+
Sbjct: 107 VDIDECTIPP-YCHQRCVNTPGSFYCQCSPGFQLAA----NNYTCVDINECDASNQCAQQ 161
Query: 609 GVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C N GSF+C C+ G+E S D +C D
Sbjct: 162 --CYNILGSFICQCNQGYELSSDRLNCED 188
Score = 109 bits (262), Expect = 4e-23
Identities = 59/182 (32%), Positives = 82/182 (45%), Gaps = 14/182 (7%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC I P C C +TP F C C G++ ++ C D++EC + QC
Sbjct: 109 IDECTI-PPYCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQ---QCY 163
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY-TLRE 186
N+ G+F C+C GY L+ CED+DEC C N G + C C GY +R
Sbjct: 164 NILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRS 223
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCH----CDDGFKAGPNNDCVDVNECREGGMV 242
C+D++EC + C N G + C+ C D + P N CV C +
Sbjct: 224 RTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCV----CPVSNAM 279
Query: 243 CR 244
CR
Sbjct: 280 CR 281
Score = 105 bits (251), Expect = 9e-22
Identities = 50/122 (40%), Positives = 65/122 (53%), Gaps = 10/122 (8%)
Query: 743 DVFADVDECAAIPGLCAP--------GRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL 794
+V D+DEC A C G F C C PGY+ GE C D+DEC + PP C Q
Sbjct: 63 NVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTI-PPYCHQR 121
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
C NT GS+ C C G++L + C D++EC+ ++ C Q C N GS+ C C GYE
Sbjct: 122 CVNTPGSFYCQCSPGFQLAANNYTCVDINECDA-SNQCAQQCYNILGSFICQCNQGYELS 180
Query: 855 GD 856
D
Sbjct: 181 SD 182
Score = 102 bits (245), Expect = 5e-21
Identities = 47/114 (41%), Positives = 59/114 (51%), Gaps = 10/114 (8%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNT 798
D+DEC IP C PG F C C PG++ A C D++EC C Q C+N
Sbjct: 108 DIDECT-IPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQCYNI 165
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
GS+ C C GYEL D NC D+DEC ++ CQ C N G + C C GY+
Sbjct: 166 LGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQ 219
Score = 95.1 bits (226), Expect = 9e-19
Identities = 67/231 (29%), Positives = 98/231 (42%), Gaps = 23/231 (9%)
Query: 254 SFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR 313
S R +CA GY ++ C+D+DEC H C D C N G + C C G++ G
Sbjct: 48 SHRIQCAAGYE-QSEHNVCQDIDECTAGTHNCRAD--QVCINLRGSFACQCPPGYQKRGE 104
Query: 314 RCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD--------ERKELC 365
+CVD DEC PY C N G + C+C G++ CVD + + C
Sbjct: 105 QCVDIDECTIPPY--CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQC 162
Query: 366 YDEWEA--GRCHRARPLQLARPECCCSEGAAWGRY-CERCPAPDSAEFMRICQGG--MGR 420
Y+ + +C++ L R C + Y C+ + +F +C G + R
Sbjct: 163 YNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVR 222
Query: 421 PNLTQDLDECRVRPDVCVGGRCVNTDGSFRC----ECPDGYVLAPDGLSCV 467
QD++EC + C N G FRC C D Y+L P+ CV
Sbjct: 223 SRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPEN-RCV 272
Score = 72.5 bits (170), Expect = 6e-12
Identities = 40/110 (36%), Positives = 53/110 (48%), Gaps = 11/110 (10%)
Query: 530 SFRCTCPYGYAVAADGVHCRDIDECVQEPRVC--PHACENVVGSYICKCPEGYRRTSAPQ 587
S R C GY + V C+DIDEC C C N+ GS+ C+CP GY++
Sbjct: 48 SHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRG--- 103
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+EC C C+NT GSF C C GF+ + + C+D
Sbjct: 104 ---EQCVDIDECTIPP-YCHQR-CVNTPGSFYCQCSPGFQLAANNYTCVD 148
Score = 69.7 bits (163), Expect = 4e-11
Identities = 31/76 (40%), Positives = 42/76 (55%), Gaps = 3/76 (3%)
Query: 786 VRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSY 843
+R P D ++ S+ C GYE E C+D+DEC TH C+ Q+C N GS+
Sbjct: 33 IRRNPADPQRIPSNPSHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSF 91
Query: 844 ECSCEDGYEKRGDACV 859
C C GY+KRG+ CV
Sbjct: 92 ACQCPPGYQKRGEQCV 107
Score = 67.7 bits (158), Expect = 2e-10
Identities = 39/119 (32%), Positives = 57/119 (47%), Gaps = 17/119 (14%)
Query: 747 DVDECAAIPGLCAP------GRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNT 798
D++EC A CA G F C C GY + + C D+DEC C C N
Sbjct: 148 DINECDA-SNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNE 206
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC----SCEDGY 851
G + C+C GY++ C+D++ECE T+ C+ ++C N G + C C+D Y
Sbjct: 207 PGKFSCMCPQGYQVVR-SRTCQDINECE-TTNECREDEMCWNYHGGFRCYPRNPCQDPY 263
>BC098561-1|AAH98561.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 169 bits (410), Expect = 5e-41
Identities = 81/201 (40%), Positives = 109/201 (54%), Gaps = 12/201 (5%)
Query: 422 NLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG 480
N+ QD+DEC C + C+N GSF C+CP GY G CVD DEC + P C
Sbjct: 169 NVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGY--QKRGEQCVDIDECTIPP-YC- 224
Query: 481 NGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGY 539
+ C NT G + CQCSPGF + TCVD++EC + C +C+N GSF C C GY
Sbjct: 225 HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQCAQQCYNILGSFICQCNQGY 283
Query: 540 AVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINEC 599
+++D ++C DIDEC +C + C N G + C CP+GY+ + C+DINEC
Sbjct: 284 ELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRS-----RTCQDINEC 338
Query: 600 EEQEDLCSGGVCINTDGSFLC 620
E + +C N G F C
Sbjct: 339 ETTNECREDEMCWNYHGGFRC 359
Score = 164 bits (398), Expect = 1e-39
Identities = 87/243 (35%), Positives = 128/243 (52%), Gaps = 22/243 (9%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GYE ++C+D+DEC+ G CR C+NL G+F C+CPPGY+ ++C D+
Sbjct: 159 CAAGYEQSE-HNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRG--EQCVDI 215
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLP 211
DEC C H C NT GS+ C+C PG+ L N C D++EC + C N+
Sbjct: 216 DECTIPPYC-HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQ--CYNIL 272
Query: 212 GAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G+++C C+ G++ + +C D++ECR +C+ +C N G F C C GY + R
Sbjct: 273 GSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGYQVVR-SR 330
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYEC----SCGAGWKLV-GRRC---VDRDECK 322
C+D++EC E + C D C N +GG+ C C + L RC V C+
Sbjct: 331 TCQDINEC-ETTNECRED--EMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCR 387
Query: 323 ELP 325
ELP
Sbjct: 388 ELP 390
Score = 140 bits (338), Expect = 3e-32
Identities = 73/186 (39%), Positives = 99/186 (53%), Gaps = 10/186 (5%)
Query: 443 VNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRIC-GNGTCSNTRGGYECQCSPGFTQ 501
+ ++ S R +C GY + + C D DEC C + C N RG + CQC PG+ +
Sbjct: 149 IPSNPSHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQK 207
Query: 502 GPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC 561
+Q CVD+DEC C RC NT GSF C C G+ +AA+ C DI+EC C
Sbjct: 208 RGEQ-CVDIDECTIP-PYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQC 264
Query: 562 PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCD 621
C N++GS+IC+C +GY +S D N CEDI+EC LC C+N G F C
Sbjct: 265 AQQCYNILGSFICQCNQGYELSS---DRLN-CEDIDECRTSSYLCQYQ-CVNEPGKFSCM 319
Query: 622 CDAGFE 627
C G++
Sbjct: 320 CPQGYQ 325
Score = 110 bits (264), Expect = 2e-23
Identities = 56/149 (37%), Positives = 72/149 (48%), Gaps = 11/149 (7%)
Query: 491 YECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHC 548
+ QC+ G+ Q C D+DEC G +C C N GSF C CP GY G C
Sbjct: 155 HRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQC 212
Query: 549 RDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSG 608
DIDEC P C C N GS+ C+C G++ + + C DINEC+
Sbjct: 213 VDIDECTIPP-YCHQRCVNTPGSFYCQCSPGFQLAA----NNYTCVDINECDASNQCAQQ 267
Query: 609 GVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C N GSF+C C+ G+E S D +C D
Sbjct: 268 --CYNILGSFICQCNQGYELSSDRLNCED 294
Score = 109 bits (262), Expect = 4e-23
Identities = 59/182 (32%), Positives = 82/182 (45%), Gaps = 14/182 (7%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC I P C C +TP F C C G++ ++ C D++EC + QC
Sbjct: 215 IDECTI-PPYCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQ---QCY 269
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY-TLRE 186
N+ G+F C+C GY L+ CED+DEC C N G + C C GY +R
Sbjct: 270 NILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRS 329
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCH----CDDGFKAGPNNDCVDVNECREGGMV 242
C+D++EC + C N G + C+ C D + P N CV C +
Sbjct: 330 RTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCV----CPVSNAM 385
Query: 243 CR 244
CR
Sbjct: 386 CR 387
Score = 105 bits (251), Expect = 9e-22
Identities = 50/122 (40%), Positives = 65/122 (53%), Gaps = 10/122 (8%)
Query: 743 DVFADVDECAAIPGLCAP--------GRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL 794
+V D+DEC A C G F C C PGY+ GE C D+DEC + PP C Q
Sbjct: 169 NVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTI-PPYCHQR 227
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
C NT GS+ C C G++L + C D++EC+ ++ C Q C N GS+ C C GYE
Sbjct: 228 CVNTPGSFYCQCSPGFQLAANNYTCVDINECDA-SNQCAQQCYNILGSFICQCNQGYELS 286
Query: 855 GD 856
D
Sbjct: 287 SD 288
Score = 102 bits (245), Expect = 5e-21
Identities = 93/359 (25%), Positives = 140/359 (38%), Gaps = 35/359 (9%)
Query: 136 RCPPGYRLTPSLDECEDVDECGD-QRICDHG-DCRNTIGSYRCECKPGYTLRENVCRDVD 193
+C GY P +C+D+DEC C G C N G Y C K + N
Sbjct: 28 QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNN--EQPQ 85
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCD----DGFKAGPNNDC-VDVNECREGGMVCRNGRC 248
+ ++P T + + + GF A ++ R ++ RN
Sbjct: 86 QETQPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPAD 145
Query: 249 RNTVGS---FRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
+ S R +CA GY ++ C+D+DEC H C D C N G + C C
Sbjct: 146 PQRIPSNPSHRIQCAAGYE-QSEHNVCQDIDECTAGTHNCRAD--QVCINLRGSFACQCP 202
Query: 306 AGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD------ 359
G++ G +CVD DEC PY C N G + C+C G++ CVD
Sbjct: 203 PGYQKRGEQCVDIDECTIPPY--CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDA 260
Query: 360 --ERKELCYDEWEA--GRCHRARPLQLARPECCCSEGAAWGRY-CERCPAPDSAEFMRIC 414
+ + CY+ + +C++ L R C + Y C+ + +F +C
Sbjct: 261 SNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMC 320
Query: 415 QGG--MGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRC----ECPDGYVLAPDGLSCV 467
G + R QD++EC + C N G FRC C D Y+L P+ CV
Sbjct: 321 PQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPEN-RCV 378
Score = 102 bits (245), Expect = 5e-21
Identities = 47/114 (41%), Positives = 59/114 (51%), Gaps = 10/114 (8%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNT 798
D+DEC IP C PG F C C PG++ A C D++EC C Q C+N
Sbjct: 214 DIDECT-IPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQCYNI 271
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
GS+ C C GYEL D NC D+DEC ++ CQ C N G + C C GY+
Sbjct: 272 LGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQ 325
Score = 83.0 bits (196), Expect = 4e-15
Identities = 70/230 (30%), Positives = 92/230 (40%), Gaps = 35/230 (15%)
Query: 425 QDLDECRVRPDVCVGG-RCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT 483
+D+DEC + PD C GG +CVN G GY+ P + +E GT
Sbjct: 43 KDIDECDIVPDACKGGMKCVNHYG--------GYLCLPKTAQIIVNNEQPQQETQPAEGT 94
Query: 484 CSNTRG--GYECQCSPGFTQG----PDQTCVDVDECAEGRASCTFRCHNTAG-------- 529
T G + G G V E GR + R N A
Sbjct: 95 SGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIR-RNPADPQRIPSNP 153
Query: 530 SFRCTCPYGYAVAADGVHCRDIDECVQEPRVC--PHACENVVGSYICKCPEGYRRTSAPQ 587
S R C GY + V C+DIDEC C C N+ GS+ C+CP GY++
Sbjct: 154 SHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRG--- 209
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+EC C C+NT GSF C C GF+ + + C+D
Sbjct: 210 ---EQCVDIDECTIPP-YCHQR-CVNTPGSFYCQCSPGFQLAANNYTCVD 254
Score = 69.7 bits (163), Expect = 4e-11
Identities = 31/76 (40%), Positives = 42/76 (55%), Gaps = 3/76 (3%)
Query: 786 VRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSY 843
+R P D ++ S+ C GYE E C+D+DEC TH C+ Q+C N GS+
Sbjct: 139 IRRNPADPQRIPSNPSHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSF 197
Query: 844 ECSCEDGYEKRGDACV 859
C C GY+KRG+ CV
Sbjct: 198 ACQCPPGYQKRGEQCV 213
Score = 67.7 bits (158), Expect = 2e-10
Identities = 39/119 (32%), Positives = 57/119 (47%), Gaps = 17/119 (14%)
Query: 747 DVDECAAIPGLCAP------GRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNT 798
D++EC A CA G F C C GY + + C D+DEC C C N
Sbjct: 254 DINECDA-SNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNE 312
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC----SCEDGY 851
G + C+C GY++ C+D++ECE T+ C+ ++C N G + C C+D Y
Sbjct: 313 PGKFSCMCPQGYQVVR-SRTCQDINECE-TTNECREDEMCWNYHGGFRCYPRNPCQDPY 369
Score = 62.1 bits (144), Expect = 8e-09
Identities = 56/196 (28%), Positives = 77/196 (39%), Gaps = 19/196 (9%)
Query: 452 ECPDGYVLAPDGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDV 510
+C DGY P C D DEC + P C G C N GGY C ++
Sbjct: 28 QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQE 87
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPY----GYAVAADGVHCRDIDECVQE--PRVCPHA 564
+ AEG + T A S T G+ +A V ++ R P
Sbjct: 88 TQPAEGTSGATTGV--VAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPAD 145
Query: 565 CENVVG--SYICKCPEGYRRTSAPQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCD 621
+ + S+ +C GY Q N C+DI+EC C + VCIN GSF C
Sbjct: 146 PQRIPSNPSHRIQCAAGYE-----QSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQ 200
Query: 622 CDAGFEPSEDGTDCID 637
C G++ + G C+D
Sbjct: 201 CPPGYQ--KRGEQCVD 214
Score = 42.7 bits (96), Expect = 0.005
Identities = 17/42 (40%), Positives = 22/42 (52%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC 135
C GYE D C+D+DEC C+G +CVN G + C
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
Score = 35.9 bits (79), Expect = 0.61
Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 2/47 (4%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRT 808
+C G + P + C D+DEC + P C C N G Y CL +T
Sbjct: 28 QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKT 74
Score = 35.9 bits (79), Expect = 0.61
Identities = 16/35 (45%), Positives = 21/35 (60%), Gaps = 1/35 (2%)
Query: 59 NPVTNETKPIDECDIMPQLCKPG-TCHDTPTGFQC 92
+PV + K IDECDI+P CK G C + G+ C
Sbjct: 36 DPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
Score = 35.5 bits (78), Expect = 0.81
Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 2/42 (4%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC 845
C GYE D C+D+DEC+ C+ C N G Y C
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
>BC014410-1|AAH14410.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 169 bits (410), Expect = 5e-41
Identities = 81/201 (40%), Positives = 109/201 (54%), Gaps = 12/201 (5%)
Query: 422 NLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG 480
N+ QD+DEC C + C+N GSF C+CP GY G CVD DEC + P C
Sbjct: 169 NVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGY--QKRGEQCVDIDECTIPP-YC- 224
Query: 481 NGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGY 539
+ C NT G + CQCSPGF + TCVD++EC + C +C+N GSF C C GY
Sbjct: 225 HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQCAQQCYNILGSFICQCNQGY 283
Query: 540 AVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINEC 599
+++D ++C DIDEC +C + C N G + C CP+GY+ + C+DINEC
Sbjct: 284 ELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRS-----RTCQDINEC 338
Query: 600 EEQEDLCSGGVCINTDGSFLC 620
E + +C N G F C
Sbjct: 339 ETTNECREDEMCWNYHGGFRC 359
Score = 164 bits (398), Expect = 1e-39
Identities = 87/243 (35%), Positives = 128/243 (52%), Gaps = 22/243 (9%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GYE ++C+D+DEC+ G CR C+NL G+F C+CPPGY+ ++C D+
Sbjct: 159 CAAGYEQSE-HNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRG--EQCVDI 215
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLP 211
DEC C H C NT GS+ C+C PG+ L N C D++EC + C N+
Sbjct: 216 DECTIPPYC-HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQ--CYNIL 272
Query: 212 GAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G+++C C+ G++ + +C D++ECR +C+ +C N G F C C GY + R
Sbjct: 273 GSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGYQVVR-SR 330
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYEC----SCGAGWKLV-GRRC---VDRDECK 322
C+D++EC E + C D C N +GG+ C C + L RC V C+
Sbjct: 331 TCQDINEC-ETTNECRED--EMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCR 387
Query: 323 ELP 325
ELP
Sbjct: 388 ELP 390
Score = 140 bits (338), Expect = 3e-32
Identities = 73/186 (39%), Positives = 99/186 (53%), Gaps = 10/186 (5%)
Query: 443 VNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRIC-GNGTCSNTRGGYECQCSPGFTQ 501
+ ++ S R +C GY + + C D DEC C + C N RG + CQC PG+ +
Sbjct: 149 IPSNPSHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQK 207
Query: 502 GPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC 561
+Q CVD+DEC C RC NT GSF C C G+ +AA+ C DI+EC C
Sbjct: 208 RGEQ-CVDIDECTIP-PYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQC 264
Query: 562 PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCD 621
C N++GS+IC+C +GY +S D N CEDI+EC LC C+N G F C
Sbjct: 265 AQQCYNILGSFICQCNQGYELSS---DRLN-CEDIDECRTSSYLCQYQ-CVNEPGKFSCM 319
Query: 622 CDAGFE 627
C G++
Sbjct: 320 CPQGYQ 325
Score = 110 bits (264), Expect = 2e-23
Identities = 56/149 (37%), Positives = 72/149 (48%), Gaps = 11/149 (7%)
Query: 491 YECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHC 548
+ QC+ G+ Q C D+DEC G +C C N GSF C CP GY G C
Sbjct: 155 HRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQC 212
Query: 549 RDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSG 608
DIDEC P C C N GS+ C+C G++ + + C DINEC+
Sbjct: 213 VDIDECTIPP-YCHQRCVNTPGSFYCQCSPGFQLAA----NNYTCVDINECDASNQCAQQ 267
Query: 609 GVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C N GSF+C C+ G+E S D +C D
Sbjct: 268 --CYNILGSFICQCNQGYELSSDRLNCED 294
Score = 109 bits (262), Expect = 4e-23
Identities = 59/182 (32%), Positives = 82/182 (45%), Gaps = 14/182 (7%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC I P C C +TP F C C G++ ++ C D++EC + QC
Sbjct: 215 IDECTI-PPYCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQ---QCY 269
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY-TLRE 186
N+ G+F C+C GY L+ CED+DEC C N G + C C GY +R
Sbjct: 270 NILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRS 329
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCH----CDDGFKAGPNNDCVDVNECREGGMV 242
C+D++EC + C N G + C+ C D + P N CV C +
Sbjct: 330 RTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCV----CPVSNAM 385
Query: 243 CR 244
CR
Sbjct: 386 CR 387
Score = 105 bits (251), Expect = 9e-22
Identities = 50/122 (40%), Positives = 65/122 (53%), Gaps = 10/122 (8%)
Query: 743 DVFADVDECAAIPGLCAP--------GRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL 794
+V D+DEC A C G F C C PGY+ GE C D+DEC + PP C Q
Sbjct: 169 NVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTI-PPYCHQR 227
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
C NT GS+ C C G++L + C D++EC+ ++ C Q C N GS+ C C GYE
Sbjct: 228 CVNTPGSFYCQCSPGFQLAANNYTCVDINECDA-SNQCAQQCYNILGSFICQCNQGYELS 286
Query: 855 GD 856
D
Sbjct: 287 SD 288
Score = 102 bits (245), Expect = 5e-21
Identities = 93/359 (25%), Positives = 140/359 (38%), Gaps = 35/359 (9%)
Query: 136 RCPPGYRLTPSLDECEDVDECGD-QRICDHG-DCRNTIGSYRCECKPGYTLRENVCRDVD 193
+C GY P +C+D+DEC C G C N G Y C K + N
Sbjct: 28 QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNN--EQPQ 85
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCD----DGFKAGPNNDC-VDVNECREGGMVCRNGRC 248
+ ++P T + + + GF A ++ R ++ RN
Sbjct: 86 QETQPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPAD 145
Query: 249 RNTVGS---FRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
+ S R +CA GY ++ C+D+DEC H C D C N G + C C
Sbjct: 146 PQRIPSNPSHRIQCAAGYE-QSEHNVCQDIDECTAGTHNCRAD--QVCINLRGSFACQCP 202
Query: 306 AGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD------ 359
G++ G +CVD DEC PY C N G + C+C G++ CVD
Sbjct: 203 PGYQKRGEQCVDIDECTIPPY--CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDA 260
Query: 360 --ERKELCYDEWEA--GRCHRARPLQLARPECCCSEGAAWGRY-CERCPAPDSAEFMRIC 414
+ + CY+ + +C++ L R C + Y C+ + +F +C
Sbjct: 261 SNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMC 320
Query: 415 QGG--MGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRC----ECPDGYVLAPDGLSCV 467
G + R QD++EC + C N G FRC C D Y+L P+ CV
Sbjct: 321 PQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPEN-RCV 378
Score = 102 bits (245), Expect = 5e-21
Identities = 47/114 (41%), Positives = 59/114 (51%), Gaps = 10/114 (8%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNT 798
D+DEC IP C PG F C C PG++ A C D++EC C Q C+N
Sbjct: 214 DIDECT-IPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQCYNI 271
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
GS+ C C GYEL D NC D+DEC ++ CQ C N G + C C GY+
Sbjct: 272 LGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQ 325
Score = 83.0 bits (196), Expect = 4e-15
Identities = 70/230 (30%), Positives = 92/230 (40%), Gaps = 35/230 (15%)
Query: 425 QDLDECRVRPDVCVGG-RCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT 483
+D+DEC + PD C GG +CVN G GY+ P + +E GT
Sbjct: 43 KDIDECDIVPDACKGGMKCVNHYG--------GYLCLPKTAQIIVNNEQPQQETQPAEGT 94
Query: 484 CSNTRG--GYECQCSPGFTQG----PDQTCVDVDECAEGRASCTFRCHNTAG-------- 529
T G + G G V E GR + R N A
Sbjct: 95 SGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIR-RNPADPQRIPSNP 153
Query: 530 SFRCTCPYGYAVAADGVHCRDIDECVQEPRVC--PHACENVVGSYICKCPEGYRRTSAPQ 587
S R C GY + V C+DIDEC C C N+ GS+ C+CP GY++
Sbjct: 154 SHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRG--- 209
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+EC C C+NT GSF C C GF+ + + C+D
Sbjct: 210 ---EQCVDIDECTIPP-YCHQR-CVNTPGSFYCQCSPGFQLAANNYTCVD 254
Score = 69.7 bits (163), Expect = 4e-11
Identities = 31/76 (40%), Positives = 42/76 (55%), Gaps = 3/76 (3%)
Query: 786 VRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSY 843
+R P D ++ S+ C GYE E C+D+DEC TH C+ Q+C N GS+
Sbjct: 139 IRRNPADPQRIPSNPSHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSF 197
Query: 844 ECSCEDGYEKRGDACV 859
C C GY+KRG+ CV
Sbjct: 198 ACQCPPGYQKRGEQCV 213
Score = 67.7 bits (158), Expect = 2e-10
Identities = 39/119 (32%), Positives = 57/119 (47%), Gaps = 17/119 (14%)
Query: 747 DVDECAAIPGLCAP------GRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNT 798
D++EC A CA G F C C GY + + C D+DEC C C N
Sbjct: 254 DINECDA-SNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNE 312
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC----SCEDGY 851
G + C+C GY++ C+D++ECE T+ C+ ++C N G + C C+D Y
Sbjct: 313 PGKFSCMCPQGYQVVR-SRTCQDINECE-TTNECREDEMCWNYHGGFRCYPRNPCQDPY 369
Score = 62.1 bits (144), Expect = 8e-09
Identities = 56/196 (28%), Positives = 77/196 (39%), Gaps = 19/196 (9%)
Query: 452 ECPDGYVLAPDGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDV 510
+C DGY P C D DEC + P C G C N GGY C ++
Sbjct: 28 QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQE 87
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPY----GYAVAADGVHCRDIDECVQE--PRVCPHA 564
+ AEG + T A S T G+ +A V ++ R P
Sbjct: 88 TQPAEGTSGATTGV--VAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPAD 145
Query: 565 CENVVG--SYICKCPEGYRRTSAPQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCD 621
+ + S+ +C GY Q N C+DI+EC C + VCIN GSF C
Sbjct: 146 PQRIPSNPSHRIQCAAGYE-----QSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQ 200
Query: 622 CDAGFEPSEDGTDCID 637
C G++ + G C+D
Sbjct: 201 CPPGYQ--KRGEQCVD 214
Score = 42.7 bits (96), Expect = 0.005
Identities = 17/42 (40%), Positives = 22/42 (52%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC 135
C GYE D C+D+DEC C+G +CVN G + C
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
Score = 35.9 bits (79), Expect = 0.61
Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 2/47 (4%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRT 808
+C G + P + C D+DEC + P C C N G Y CL +T
Sbjct: 28 QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKT 74
Score = 35.9 bits (79), Expect = 0.61
Identities = 16/35 (45%), Positives = 21/35 (60%), Gaps = 1/35 (2%)
Query: 59 NPVTNETKPIDECDIMPQLCKPG-TCHDTPTGFQC 92
+PV + K IDECDI+P CK G C + G+ C
Sbjct: 36 DPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
Score = 35.5 bits (78), Expect = 0.81
Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 2/42 (4%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC 845
C GYE D C+D+DEC+ C+ C N G Y C
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
>AY004330-1|AAK11491.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 169 bits (410), Expect = 5e-41
Identities = 81/201 (40%), Positives = 109/201 (54%), Gaps = 12/201 (5%)
Query: 422 NLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG 480
N+ QD+DEC C + C+N GSF C+CP GY G CVD DEC + P C
Sbjct: 169 NVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGY--QKRGEQCVDIDECTIPP-YC- 224
Query: 481 NGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGY 539
+ C NT G + CQCSPGF + TCVD++EC + C +C+N GSF C C GY
Sbjct: 225 HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQCAQQCYNILGSFICQCNQGY 283
Query: 540 AVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINEC 599
+++D ++C DIDEC +C + C N G + C CP+GY+ + C+DINEC
Sbjct: 284 ELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRS-----RTCQDINEC 338
Query: 600 EEQEDLCSGGVCINTDGSFLC 620
E + +C N G F C
Sbjct: 339 ETTNECREDEMCWNYHGGFRC 359
Score = 164 bits (398), Expect = 1e-39
Identities = 87/243 (35%), Positives = 128/243 (52%), Gaps = 22/243 (9%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GYE ++C+D+DEC+ G CR C+NL G+F C+CPPGY+ ++C D+
Sbjct: 159 CAAGYEQSE-HNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRG--EQCVDI 215
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLP 211
DEC C H C NT GS+ C+C PG+ L N C D++EC + C N+
Sbjct: 216 DECTIPPYC-HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQ--CYNIL 272
Query: 212 GAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G+++C C+ G++ + +C D++ECR +C+ +C N G F C C GY + R
Sbjct: 273 GSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGYQVVR-SR 330
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYEC----SCGAGWKLV-GRRC---VDRDECK 322
C+D++EC E + C D C N +GG+ C C + L RC V C+
Sbjct: 331 TCQDINEC-ETTNECRED--EMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCR 387
Query: 323 ELP 325
ELP
Sbjct: 388 ELP 390
Score = 140 bits (338), Expect = 3e-32
Identities = 73/186 (39%), Positives = 99/186 (53%), Gaps = 10/186 (5%)
Query: 443 VNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRIC-GNGTCSNTRGGYECQCSPGFTQ 501
+ ++ S R +C GY + + C D DEC C + C N RG + CQC PG+ +
Sbjct: 149 IPSNPSHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQK 207
Query: 502 GPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC 561
+Q CVD+DEC C RC NT GSF C C G+ +AA+ C DI+EC C
Sbjct: 208 RGEQ-CVDIDECTIP-PYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQC 264
Query: 562 PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCD 621
C N++GS+IC+C +GY +S D N CEDI+EC LC C+N G F C
Sbjct: 265 AQQCYNILGSFICQCNQGYELSS---DRLN-CEDIDECRTSSYLCQYQ-CVNEPGKFSCM 319
Query: 622 CDAGFE 627
C G++
Sbjct: 320 CPQGYQ 325
Score = 110 bits (264), Expect = 2e-23
Identities = 56/149 (37%), Positives = 72/149 (48%), Gaps = 11/149 (7%)
Query: 491 YECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHC 548
+ QC+ G+ Q C D+DEC G +C C N GSF C CP GY G C
Sbjct: 155 HRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQC 212
Query: 549 RDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSG 608
DIDEC P C C N GS+ C+C G++ + + C DINEC+
Sbjct: 213 VDIDECTIPP-YCHQRCVNTPGSFYCQCSPGFQLAA----NNYTCVDINECDASNQCAQQ 267
Query: 609 GVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C N GSF+C C+ G+E S D +C D
Sbjct: 268 --CYNILGSFICQCNQGYELSSDRLNCED 294
Score = 109 bits (262), Expect = 4e-23
Identities = 59/182 (32%), Positives = 82/182 (45%), Gaps = 14/182 (7%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC I P C C +TP F C C G++ ++ C D++EC + QC
Sbjct: 215 IDECTI-PPYCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQ---QCY 269
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY-TLRE 186
N+ G+F C+C GY L+ CED+DEC C N G + C C GY +R
Sbjct: 270 NILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRS 329
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCH----CDDGFKAGPNNDCVDVNECREGGMV 242
C+D++EC + C N G + C+ C D + P N CV C +
Sbjct: 330 RTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCV----CPVSNAM 385
Query: 243 CR 244
CR
Sbjct: 386 CR 387
Score = 105 bits (251), Expect = 9e-22
Identities = 50/122 (40%), Positives = 65/122 (53%), Gaps = 10/122 (8%)
Query: 743 DVFADVDECAAIPGLCAP--------GRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL 794
+V D+DEC A C G F C C PGY+ GE C D+DEC + PP C Q
Sbjct: 169 NVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTI-PPYCHQR 227
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
C NT GS+ C C G++L + C D++EC+ ++ C Q C N GS+ C C GYE
Sbjct: 228 CVNTPGSFYCQCSPGFQLAANNYTCVDINECDA-SNQCAQQCYNILGSFICQCNQGYELS 286
Query: 855 GD 856
D
Sbjct: 287 SD 288
Score = 102 bits (245), Expect = 5e-21
Identities = 93/359 (25%), Positives = 140/359 (38%), Gaps = 35/359 (9%)
Query: 136 RCPPGYRLTPSLDECEDVDECGD-QRICDHG-DCRNTIGSYRCECKPGYTLRENVCRDVD 193
+C GY P +C+D+DEC C G C N G Y C K + N
Sbjct: 28 QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNN--EQPQ 85
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCD----DGFKAGPNNDC-VDVNECREGGMVCRNGRC 248
+ ++P T + + + GF A ++ R ++ RN
Sbjct: 86 QETQPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPAD 145
Query: 249 RNTVGS---FRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
+ S R +CA GY ++ C+D+DEC H C D C N G + C C
Sbjct: 146 PQRIPSNPSHRIQCAAGYE-QSEHNVCQDIDECTAGTHNCRAD--QVCINLRGSFACQCP 202
Query: 306 AGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD------ 359
G++ G +CVD DEC PY C N G + C+C G++ CVD
Sbjct: 203 PGYQKRGEQCVDIDECTIPPY--CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDA 260
Query: 360 --ERKELCYDEWEA--GRCHRARPLQLARPECCCSEGAAWGRY-CERCPAPDSAEFMRIC 414
+ + CY+ + +C++ L R C + Y C+ + +F +C
Sbjct: 261 SNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMC 320
Query: 415 QGG--MGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRC----ECPDGYVLAPDGLSCV 467
G + R QD++EC + C N G FRC C D Y+L P+ CV
Sbjct: 321 PQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPEN-RCV 378
Score = 102 bits (245), Expect = 5e-21
Identities = 47/114 (41%), Positives = 59/114 (51%), Gaps = 10/114 (8%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNT 798
D+DEC IP C PG F C C PG++ A C D++EC C Q C+N
Sbjct: 214 DIDECT-IPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQCYNI 271
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
GS+ C C GYEL D NC D+DEC ++ CQ C N G + C C GY+
Sbjct: 272 LGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQ 325
Score = 83.0 bits (196), Expect = 4e-15
Identities = 70/230 (30%), Positives = 92/230 (40%), Gaps = 35/230 (15%)
Query: 425 QDLDECRVRPDVCVGG-RCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGT 483
+D+DEC + PD C GG +CVN G GY+ P + +E GT
Sbjct: 43 KDIDECDIVPDACKGGMKCVNHYG--------GYLCLPKTAQIIVNNEQPQQETQPAEGT 94
Query: 484 CSNTRG--GYECQCSPGFTQG----PDQTCVDVDECAEGRASCTFRCHNTAG-------- 529
T G + G G V E GR + R N A
Sbjct: 95 SGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIR-RNPADPQRIPSNP 153
Query: 530 SFRCTCPYGYAVAADGVHCRDIDECVQEPRVC--PHACENVVGSYICKCPEGYRRTSAPQ 587
S R C GY + V C+DIDEC C C N+ GS+ C+CP GY++
Sbjct: 154 SHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRG--- 209
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+EC C C+NT GSF C C GF+ + + C+D
Sbjct: 210 ---EQCVDIDECTIPP-YCHQR-CVNTPGSFYCQCSPGFQLAANNYTCVD 254
Score = 69.7 bits (163), Expect = 4e-11
Identities = 31/76 (40%), Positives = 42/76 (55%), Gaps = 3/76 (3%)
Query: 786 VRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSY 843
+R P D ++ S+ C GYE E C+D+DEC TH C+ Q+C N GS+
Sbjct: 139 IRRNPADPQRIPSNPSHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSF 197
Query: 844 ECSCEDGYEKRGDACV 859
C C GY+KRG+ CV
Sbjct: 198 ACQCPPGYQKRGEQCV 213
Score = 67.7 bits (158), Expect = 2e-10
Identities = 39/119 (32%), Positives = 57/119 (47%), Gaps = 17/119 (14%)
Query: 747 DVDECAAIPGLCAP------GRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNT 798
D++EC A CA G F C C GY + + C D+DEC C C N
Sbjct: 254 DINECDA-SNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNE 312
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC----SCEDGY 851
G + C+C GY++ C+D++ECE T+ C+ ++C N G + C C+D Y
Sbjct: 313 PGKFSCMCPQGYQVVR-SRTCQDINECE-TTNECREDEMCWNYHGGFRCYPRNPCQDPY 369
Score = 62.1 bits (144), Expect = 8e-09
Identities = 56/196 (28%), Positives = 77/196 (39%), Gaps = 19/196 (9%)
Query: 452 ECPDGYVLAPDGLSCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVDV 510
+C DGY P C D DEC + P C G C N GGY C ++
Sbjct: 28 QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQE 87
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPY----GYAVAADGVHCRDIDECVQE--PRVCPHA 564
+ AEG + T A S T G+ +A V ++ R P
Sbjct: 88 TQPAEGTSGATTGV--VAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPAD 145
Query: 565 CENVVG--SYICKCPEGYRRTSAPQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCD 621
+ + S+ +C GY Q N C+DI+EC C + VCIN GSF C
Sbjct: 146 PQRIPSNPSHRIQCAAGYE-----QSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQ 200
Query: 622 CDAGFEPSEDGTDCID 637
C G++ + G C+D
Sbjct: 201 CPPGYQ--KRGEQCVD 214
Score = 42.7 bits (96), Expect = 0.005
Identities = 17/42 (40%), Positives = 22/42 (52%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC 135
C GYE D C+D+DEC C+G +CVN G + C
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
Score = 35.9 bits (79), Expect = 0.61
Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 2/47 (4%)
Query: 764 RCVCGPGYRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRT 808
+C G + P + C D+DEC + P C C N G Y CL +T
Sbjct: 28 QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKT 74
Score = 35.9 bits (79), Expect = 0.61
Identities = 16/35 (45%), Positives = 21/35 (60%), Gaps = 1/35 (2%)
Query: 59 NPVTNETKPIDECDIMPQLCKPG-TCHDTPTGFQC 92
+PV + K IDECDI+P CK G C + G+ C
Sbjct: 36 DPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
Score = 35.5 bits (78), Expect = 0.81
Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 2/42 (4%)
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC 845
C GYE D C+D+DEC+ C+ C N G Y C
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
>AB209212-1|BAD92449.1| 418|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 isoform b
variant protein.
Length = 418
Score = 169 bits (410), Expect = 5e-41
Identities = 81/201 (40%), Positives = 109/201 (54%), Gaps = 12/201 (5%)
Query: 422 NLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG 480
N+ QD+DEC C + C+N GSF C+CP GY G CVD DEC + P C
Sbjct: 94 NVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGY--QKRGEQCVDIDECTIPP-YC- 149
Query: 481 NGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGY 539
+ C NT G + CQCSPGF + TCVD++EC + C +C+N GSF C C GY
Sbjct: 150 HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQCAQQCYNILGSFICQCNQGY 208
Query: 540 AVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINEC 599
+++D ++C DIDEC +C + C N G + C CP+GY+ + C+DINEC
Sbjct: 209 ELSSDRLNCEDIDECRTSSYLCQYQCVNQPGKFSCMCPQGYQVVRS-----RTCQDINEC 263
Query: 600 EEQEDLCSGGVCINTDGSFLC 620
E + +C N G F C
Sbjct: 264 ETTNECREDEMCWNYHGGFRC 284
Score = 164 bits (398), Expect = 1e-39
Identities = 87/243 (35%), Positives = 128/243 (52%), Gaps = 22/243 (9%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GYE ++C+D+DEC+ G CR C+NL G+F C+CPPGY+ ++C D+
Sbjct: 84 CAAGYEQSE-HNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRG--EQCVDI 140
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLP 211
DEC C H C NT GS+ C+C PG+ L N C D++EC + C N+
Sbjct: 141 DECTIPPYC-HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQ--CYNIL 197
Query: 212 GAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G+++C C+ G++ + +C D++ECR +C+ +C N G F C C GY + R
Sbjct: 198 GSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVNQPGKFSCMCPQGYQVVR-SR 255
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYEC----SCGAGWKLV-GRRC---VDRDECK 322
C+D++EC E + C D C N +GG+ C C + L RC V C+
Sbjct: 256 TCQDINEC-ETTNECRED--EMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCR 312
Query: 323 ELP 325
ELP
Sbjct: 313 ELP 315
Score = 140 bits (338), Expect = 3e-32
Identities = 73/186 (39%), Positives = 99/186 (53%), Gaps = 10/186 (5%)
Query: 443 VNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRIC-GNGTCSNTRGGYECQCSPGFTQ 501
+ ++ S R +C GY + + C D DEC C + C N RG + CQC PG+ +
Sbjct: 74 IPSNPSHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQK 132
Query: 502 GPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC 561
+Q CVD+DEC C RC NT GSF C C G+ +AA+ C DI+EC C
Sbjct: 133 RGEQ-CVDIDECTIP-PYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQC 189
Query: 562 PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCD 621
C N++GS+IC+C +GY +S D N CEDI+EC LC C+N G F C
Sbjct: 190 AQQCYNILGSFICQCNQGYELSS---DRLN-CEDIDECRTSSYLCQYQ-CVNQPGKFSCM 244
Query: 622 CDAGFE 627
C G++
Sbjct: 245 CPQGYQ 250
Score = 110 bits (264), Expect = 2e-23
Identities = 56/149 (37%), Positives = 72/149 (48%), Gaps = 11/149 (7%)
Query: 491 YECQCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHC 548
+ QC+ G+ Q C D+DEC G +C C N GSF C CP GY G C
Sbjct: 80 HRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQC 137
Query: 549 RDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSG 608
DIDEC P C C N GS+ C+C G++ + + C DINEC+
Sbjct: 138 VDIDECTIPP-YCHQRCVNTPGSFYCQCSPGFQLAA----NNYTCVDINECDASNQCAQQ 192
Query: 609 GVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C N GSF+C C+ G+E S D +C D
Sbjct: 193 --CYNILGSFICQCNQGYELSSDRLNCED 219
Score = 109 bits (262), Expect = 4e-23
Identities = 59/182 (32%), Positives = 82/182 (45%), Gaps = 14/182 (7%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC I P C C +TP F C C G++ ++ C D++EC + QC
Sbjct: 140 IDECTI-PPYCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQ---QCY 194
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY-TLRE 186
N+ G+F C+C GY L+ CED+DEC C N G + C C GY +R
Sbjct: 195 NILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNQPGKFSCMCPQGYQVVRS 254
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCH----CDDGFKAGPNNDCVDVNECREGGMV 242
C+D++EC + C N G + C+ C D + P N CV C +
Sbjct: 255 RTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCV----CPVSNAM 310
Query: 243 CR 244
CR
Sbjct: 311 CR 312
Score = 105 bits (251), Expect = 9e-22
Identities = 50/122 (40%), Positives = 65/122 (53%), Gaps = 10/122 (8%)
Query: 743 DVFADVDECAAIPGLCAP--------GRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL 794
+V D+DEC A C G F C C PGY+ GE C D+DEC + PP C Q
Sbjct: 94 NVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTI-PPYCHQR 152
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
C NT GS+ C C G++L + C D++EC+ ++ C Q C N GS+ C C GYE
Sbjct: 153 CVNTPGSFYCQCSPGFQLAANNYTCVDINECDA-SNQCAQQCYNILGSFICQCNQGYELS 211
Query: 855 GD 856
D
Sbjct: 212 SD 213
Score = 102 bits (245), Expect = 5e-21
Identities = 47/114 (41%), Positives = 59/114 (51%), Gaps = 10/114 (8%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNT 798
D+DEC IP C PG F C C PG++ A C D++EC C Q C+N
Sbjct: 139 DIDECT-IPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQCYNI 196
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
GS+ C C GYEL D NC D+DEC ++ CQ C N G + C C GY+
Sbjct: 197 LGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNQPGKFSCMCPQGYQ 250
Score = 95.5 bits (227), Expect = 7e-19
Identities = 77/271 (28%), Positives = 105/271 (38%), Gaps = 42/271 (15%)
Query: 254 SFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR 313
S R +CA GY ++ C+D+DEC H C D C N G + C C G++ G
Sbjct: 79 SHRIQCAAGYE-QSEHNVCQDIDECTAGTHNCRAD--QVCINLRGSFACQCPPGYQKRGE 135
Query: 314 RCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGR 373
+CVD DEC PY C N G + C+C G++ CVD E A +
Sbjct: 136 QCVDIDECTIPPY--CHQRCVNTPGSFYCQCSPGFQLAANNYTCVD-INECDASNQCAQQ 192
Query: 374 CHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVR 433
C+ L C C++G + +R D E CR
Sbjct: 193 CYNI----LGSFICQCNQG--YELSSDRLNCEDIDE--------------------CRTS 226
Query: 434 PDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYEC 493
+C +CVN G F C CP GY + +C D +EC + C N GG+ C
Sbjct: 227 SYLC-QYQCVNQPGKFSCMCPQGYQVV-RSRTCQDINECETTNECREDEMCWNYHGGFRC 284
Query: 494 ----QCSPGFTQGPDQTCVDVDECAEGRASC 520
C + P+ CV C A C
Sbjct: 285 YPRNPCQDPYILTPENRCV----CPVSNAMC 311
Score = 72.5 bits (170), Expect = 6e-12
Identities = 40/110 (36%), Positives = 53/110 (48%), Gaps = 11/110 (10%)
Query: 530 SFRCTCPYGYAVAADGVHCRDIDECVQEPRVC--PHACENVVGSYICKCPEGYRRTSAPQ 587
S R C GY + V C+DIDEC C C N+ GS+ C+CP GY++
Sbjct: 79 SHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRG--- 134
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C DI+EC C C+NT GSF C C GF+ + + C+D
Sbjct: 135 ---EQCVDIDECTIPP-YCHQR-CVNTPGSFYCQCSPGFQLAANNYTCVD 179
Score = 69.7 bits (163), Expect = 4e-11
Identities = 31/76 (40%), Positives = 42/76 (55%), Gaps = 3/76 (3%)
Query: 786 VRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSY 843
+R P D ++ S+ C GYE E C+D+DEC TH C+ Q+C N GS+
Sbjct: 64 IRRNPADPQRIPSNPSHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSF 122
Query: 844 ECSCEDGYEKRGDACV 859
C C GY+KRG+ CV
Sbjct: 123 ACQCPPGYQKRGEQCV 138
Score = 67.7 bits (158), Expect = 2e-10
Identities = 39/119 (32%), Positives = 57/119 (47%), Gaps = 17/119 (14%)
Query: 747 DVDECAAIPGLCAP------GRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNT 798
D++EC A CA G F C C GY + + C D+DEC C C N
Sbjct: 179 DINECDA-SNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNQ 237
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC----SCEDGY 851
G + C+C GY++ C+D++ECE T+ C+ ++C N G + C C+D Y
Sbjct: 238 PGKFSCMCPQGYQVVR-SRTCQDINECE-TTNECREDEMCWNYHGGFRCYPRNPCQDPY 294
>AY358898-1|AAQ89257.1| 448|Homo sapiens FBLN5 protein.
Length = 448
Score = 167 bits (405), Expect = 2e-40
Identities = 88/213 (41%), Positives = 109/213 (51%), Gaps = 15/213 (7%)
Query: 413 ICQGG--MGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDA 469
IC+ G M N D+DEC C + C+NT+G + C C DGY L +G C+D
Sbjct: 112 ICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLL-EG-QCLDI 169
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTA 528
DEC C C+N G Y C C+PGFT D ++C DV+ECA C C NT
Sbjct: 170 DECRYG--YCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENP-CVQTCVNTY 225
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQD 588
GS C C GY + DGVHC D+DEC +C H C N G+Y C CP GY D
Sbjct: 226 GSLICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGY----ILLD 281
Query: 589 SENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
+C+DINECE + C+ C N G F C
Sbjct: 282 DNRSCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 159 bits (387), Expect = 3e-38
Identities = 79/212 (37%), Positives = 112/212 (52%), Gaps = 13/212 (6%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GY+ D S+ C DVDEC+ C C+N G + C C GY L +C D+
Sbjct: 113 CRFGYQMDE-SNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEG--QCLDI 169
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLP 211
DEC C C N GSY C C PG+TL E+ C+DV+EC+ P + TC N
Sbjct: 170 DECR-YGYCQQL-CANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ--TCVNTY 225
Query: 212 GAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G+ +C CD G++ + C D++EC +C++ C N G++ C C PGY L D R
Sbjct: 226 GSLICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNR 284
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYEC 302
+C+D++EC+ H C +C N GG++C
Sbjct: 285 SCQDINECEHRNHTCNL--QQTCYNLQGGFKC 314
Score = 156 bits (379), Expect = 3e-37
Identities = 97/272 (35%), Positives = 124/272 (45%), Gaps = 16/272 (5%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC--RCPPG 140
C +P Q C +G++ D S C D+DEC CRG CVN G + C R P
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPV 75
Query: 141 YRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE-NVCRDVDECSRPR 199
YR S S C+ GY + E N C DVDEC+
Sbjct: 76 YRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDS 135
Query: 200 PVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCE 258
C C N G Y C C DG+ C+D++ECR G C+ C N GS+ C
Sbjct: 136 HQCNPTQICINTEGGYTCSCTDGYWL-LEGQCLDIDECRYG--YCQQ-LCANVPGSYSCT 191
Query: 259 CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCV 316
C PG+TL DGR+C+DV+EC +PC + +C NT G C C G++L G C
Sbjct: 192 CNPGFTLNEDGRSCQDVNEC-ATENPCVQ----TCVNTYGSLICRCDPGYELEEDGVHCS 246
Query: 317 DRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
D DEC ++C EC N G Y C CP G+
Sbjct: 247 DMDECSFSEFLCQ-HECVNQPGTYFCSCPPGY 277
Score = 147 bits (355), Expect = 2e-34
Identities = 84/215 (39%), Positives = 105/215 (48%), Gaps = 16/215 (7%)
Query: 137 CPPGYRLTPSLDECEDVDECG-DQRICDHGD-CRNTIGSYRCECKPGYTLRENVCRDVDE 194
C GY++ S ++C DVDEC D C+ C NT G Y C C GY L E C D+DE
Sbjct: 113 CRFGYQMDES-NQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDE 171
Query: 195 CSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVG 253
C C+ C N+PG+Y C C+ GF + C DVNEC + C NT G
Sbjct: 172 CRYG--YCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQT--CVNTYG 226
Query: 254 SFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV-- 311
S C C PGY L DG +C D+DEC C + C N G Y CSC G+ L+
Sbjct: 227 SLICRCDPGYELEEDGVHCSDMDECSFSEFLCQHE----CVNQPGTYFCSCPPGYILLDD 282
Query: 312 GRRCVDRDECKELPYVC-AGGECRNFNGGYVCECP 345
R C D +EC+ + C C N GG+ C P
Sbjct: 283 NRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDP 317
Score = 143 bits (347), Expect = 2e-33
Identities = 78/218 (35%), Positives = 103/218 (47%), Gaps = 17/218 (7%)
Query: 62 TNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPC 120
+N+ +DEC C P C +T G+ C C GY C D+DEC +G C
Sbjct: 122 SNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYW--LLEGQCLDIDECRYGY--C 177
Query: 121 RGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKP 180
+ + C N+PG++ C C PG+ L C+DV+EC + C C NT GS C C P
Sbjct: 178 QQL--CANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ-TCVNTYGSLICRCDP 234
Query: 181 GYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF-KAGPNNDCVDVNECR 237
GY L E+ C D+DECS +C++ C N PG Y C C G+ N C D+NEC
Sbjct: 235 GYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINECE 293
Query: 238 EGGMVCR-NGRCRNTVGSFRC----ECAPGYTLTADGR 270
C C N G F+C C Y +D R
Sbjct: 294 HRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNR 331
Score = 138 bits (334), Expect = 8e-32
Identities = 71/186 (38%), Positives = 93/186 (50%), Gaps = 11/186 (5%)
Query: 453 CPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTCVDVD 511
C GY + + CVD DECA D C C NT GGY C C+ G+ Q C+D+D
Sbjct: 113 CRFGYQM-DESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQ-CLDID 170
Query: 512 ECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGS 571
EC G C C N GS+ CTC G+ + DG C+D++EC E C C N GS
Sbjct: 171 ECRYGY--CQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATE-NPCVQTCVNTYGS 227
Query: 572 YICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSED 631
IC+C GY +D + C D++EC E LC C+N G++ C C G+ +D
Sbjct: 228 LICRCDPGYE---LEEDGVH-CSDMDECSFSEFLCQHE-CVNQPGTYFCSCPPGYILLDD 282
Query: 632 GTDCID 637
C D
Sbjct: 283 NRSCQD 288
Score = 114 bits (274), Expect = 1e-24
Identities = 94/338 (27%), Positives = 128/338 (37%), Gaps = 44/338 (13%)
Query: 207 CENLPGAYLCHCDDGFKAG-PNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCECAPGYT 264
C PG C +GF + C+D++ECR CR C N G + C P
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC--IPRTN 73
Query: 265 LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL-VGRRCVDRDECKE 323
G P+P + C G+++ +CVD DEC
Sbjct: 74 PVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECAT 133
Query: 324 LPYVCAGGE-CRNFNGGYVCECPAG-WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQ 381
+ C + C N GGY C C G W + C+D DE G C +
Sbjct: 134 DSHQCNPTQICINTEGGYTCSCTDGYWLLE---GQCLD------IDECRYGYCQQLCANV 184
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
C C+ G C QD++EC + CV
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSC----------------------QDVNECATE-NPCVQ-T 220
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
CVNT GS C C GY L DG+ C D DEC+ +C + C N G Y C C PG+
Sbjct: 221 CVNTYGSLICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYIL 279
Query: 502 GPD-QTCVDVDECAEGRASCTFR--CHNTAGSFRCTCP 536
D ++C D++EC +C + C+N G F+C P
Sbjct: 280 LDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDP 317
Score = 109 bits (261), Expect = 5e-23
Identities = 53/111 (47%), Positives = 61/111 (54%), Gaps = 7/111 (6%)
Query: 747 DVDEC--AAIPGLCA--PGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDG 800
D+DEC LCA PG + C C PG+ G C DV+ECA P C Q C NT G
Sbjct: 168 DIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENP-CVQTCVNTYG 226
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
S C C GYEL+EDG +C D+DEC CQ C N G+Y CSC GY
Sbjct: 227 SLICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGY 277
Score = 109 bits (261), Expect = 5e-23
Identities = 59/172 (34%), Positives = 86/172 (50%), Gaps = 15/172 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC C+ C + P + C C+ G+ + C+DV+EC+ P C + CV
Sbjct: 169 IDECRY--GYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENP-C--VQTCV 222
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECG-DQRICDHGDCRNTIGSYRCECKPGYTLRE 186
N G+ CRC PGY L C D+DEC + +C H +C N G+Y C C PGY L +
Sbjct: 223 NTYGSLICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLD 281
Query: 187 N--VCRDVDECSRPRPVCR-NGTCENLPGAYLC----HCDDGFKAGPNNDCV 231
+ C+D++EC C TC NL G + C C++ + +N C+
Sbjct: 282 DNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCM 333
Score = 104 bits (249), Expect = 2e-21
Identities = 98/342 (28%), Positives = 133/342 (38%), Gaps = 47/342 (13%)
Query: 123 MAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD--CRNTIGSYRCECKP 180
+A C+ PG + +C G+ L +C D+DEC GD C N G Y C +
Sbjct: 13 LALCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRT 72
Query: 181 GYTLRENVCRDVD-ECSRPRPVCRNG-TCENLPG-AYLCHCDDGFKAGPNNDCVDVNECR 237
R S P P + N P + C G++ +N CVDV+EC
Sbjct: 73 NPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECA 132
Query: 238 EGGMVCRNGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
C + C NT G + C C GY L +G+ C D+DEC C C N
Sbjct: 133 TDSHQCNPTQICINTEGGYTCSCTDGYWL-LEGQ-CLDIDECRY--GYC----QQLCANV 184
Query: 297 NGGYECSCGAGWKL--VGRRCVDRDEC-KELPYVCAGGECRNFNGGYVCECPAGWRFDKT 353
G Y C+C G+ L GR C D +EC E P V C N G +C C G+ ++
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSCQDVNECATENPCV---QTCVNTYGSLICRCDPGYELEED 241
Query: 354 AAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRI 413
C D E + E+ L + EC G +C P + R
Sbjct: 242 GVHCSD-MDECSFSEF------------LCQHECVNQPGT---YFCSCPPGYILLDDNRS 285
Query: 414 CQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECP 454
C QD++EC R C + C N G F+C P
Sbjct: 286 C----------QDINECEHRNHTCNLQQTCYNLQGGFKCIDP 317
Score = 85.4 bits (202), Expect = 8e-16
Identities = 47/123 (38%), Positives = 62/123 (50%), Gaps = 13/123 (10%)
Query: 747 DVDECAA---IPGLCAP--GRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTD 799
DV+ECA C G C C PGY G C+D+DEC+ C C N
Sbjct: 207 DVNECATENPCVQTCVNTYGSLICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQP 266
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC----SCEDGYEK 853
G+Y C C GY L +D +C+D++ECE HTC QQ C N +G ++C CE+ Y +
Sbjct: 267 GTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLR 326
Query: 854 RGD 856
D
Sbjct: 327 ISD 329
Score = 82.2 bits (194), Expect = 7e-15
Identities = 46/112 (41%), Positives = 56/112 (50%), Gaps = 11/112 (9%)
Query: 752 AAIPGLCAPG----RFRCVCGPGYR-PAGEVCADVDECAVRPPPCD--QLCHNTDGSYDC 804
AA P L AP +C GY+ C DVDECA C+ Q+C NT+G Y C
Sbjct: 94 AAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTC 153
Query: 805 LCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C GY L E C D+DEC CQQ+C+N GSY C+C G+ D
Sbjct: 154 SCTDGYWLLE--GQCLDIDECRYGY--CQQLCANVPGSYSCTCNPGFTLNED 201
Score = 44.4 bits (100), Expect = 0.002
Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC 845
LC + G+ C G++LD C D+DEC C+ +C N G Y C
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC 68
Score = 41.9 bits (94), Expect = 0.009
Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 6/57 (10%)
Query: 757 LCAPGRFRCVCGPGY---RPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRT 808
L +PG + C G+ R +G+ C D+DEC P C D +C N +G Y C+ RT
Sbjct: 17 LPSPGNAQAQCTNGFDLDRQSGQ-CLDIDECRTIPEACRGDMMCVNQNGGYLCIPRT 72
Score = 35.5 bits (78), Expect = 0.81
Identities = 17/53 (32%), Positives = 23/53 (43%), Gaps = 2/53 (3%)
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC--PHACENVVGSYIC 574
C + G+ + C G+ + C DIDEC P C C N G Y+C
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC 68
Score = 32.3 bits (70), Expect = 7.5
Identities = 12/29 (41%), Positives = 18/29 (62%), Gaps = 1/29 (3%)
Query: 593 CEDINECEEQEDLCSGG-VCINTDGSFLC 620
C DI+EC + C G +C+N +G +LC
Sbjct: 40 CLDIDECRTIPEACRGDMMCVNQNGGYLC 68
>AF093118-1|AAC62107.1| 448|Homo sapiens UP50 protein.
Length = 448
Score = 165 bits (402), Expect = 4e-40
Identities = 88/213 (41%), Positives = 108/213 (50%), Gaps = 15/213 (7%)
Query: 413 ICQGG--MGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDA 469
IC+ G M N D+DEC C + C+N G + C C DGY L +G C+D
Sbjct: 112 ICRFGYQMDESNQCVDVDECATDSHQCNPTQICINMKGGYTCSCTDGYWLL-EG-QCLDI 169
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTA 528
DEC C C+N G Y C C+PGFT D ++C DV+ECA C C NT
Sbjct: 170 DECRYG--YCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENP-CVQTCVNTY 225
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQD 588
GSF C C GY + DGVHC D+DEC +C H C N G+Y C CP GY D
Sbjct: 226 GSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGY----ILLD 281
Query: 589 SENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
+C+DINECE + C+ C N G F C
Sbjct: 282 DNRSCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 162 bits (394), Expect = 4e-39
Identities = 79/212 (37%), Positives = 114/212 (53%), Gaps = 13/212 (6%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GY+ D S+ C DVDEC+ C C+N+ G + C C GY L +C D+
Sbjct: 113 CRFGYQMDE-SNQCVDVDECATDSHQCNPTQICINMKGGYTCSCTDGYWLLEG--QCLDI 169
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLP 211
DEC C C N GSY C C PG+TL E+ C+DV+EC+ P + TC N
Sbjct: 170 DECR-YGYCQQL-CANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ--TCVNTY 225
Query: 212 GAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGR 270
G+++C CD G++ + C D++EC +C++ C N G++ C C PGY L D R
Sbjct: 226 GSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNR 284
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYEC 302
+C+D++EC+ H C +C N GG++C
Sbjct: 285 SCQDINECEHRNHTCNL--QQTCYNLQGGFKC 314
Score = 159 bits (386), Expect = 4e-38
Identities = 97/272 (35%), Positives = 126/272 (46%), Gaps = 16/272 (5%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC--RCPPG 140
C +P Q C +G++ D S C D+DEC CRG CVN G + C R P
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCHSRTNPV 75
Query: 141 YRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE-NVCRDVDECSRPR 199
YR S S C+ GY + E N C DVDEC+
Sbjct: 76 YRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDS 135
Query: 200 PVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCE 258
C C N+ G Y C C DG+ C+D++ECR G C+ C N GS+ C
Sbjct: 136 HQCNPTQICINMKGGYTCSCTDGYWL-LEGQCLDIDECRYG--YCQQ-LCANVPGSYSCT 191
Query: 259 CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCV 316
C PG+TL DGR+C+DV+EC +PC + +C NT G + C C G++L G C
Sbjct: 192 CNPGFTLNEDGRSCQDVNEC-ATENPCVQ----TCVNTYGSFICRCDPGYELEEDGVHCS 246
Query: 317 DRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
D DEC ++C EC N G Y C CP G+
Sbjct: 247 DMDECSFSEFLCQ-HECVNQPGTYFCSCPPGY 277
Score = 149 bits (361), Expect = 4e-35
Identities = 100/292 (34%), Positives = 132/292 (45%), Gaps = 31/292 (10%)
Query: 68 IDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRP---PCRGM 123
IDEC +P+ C+ C + G+ C H T+ + R + P P
Sbjct: 43 IDECRTIPEACRGDMMCVNQNGGYLC-------HSRTNPVYRGPYSNPYSTPYSGPYPAA 95
Query: 124 AQCVNLPG----AFECRCPPGYRLTPSLDECEDVDECG-DQRICDHGD-CRNTIGSYRCE 177
A ++ P + C GY++ S ++C DVDEC D C+ C N G Y C
Sbjct: 96 APPLSAPNYPTISRPLICRFGYQMDES-NQCVDVDECATDSHQCNPTQICINMKGGYTCS 154
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNEC 236
C GY L E C D+DEC C+ C N+PG+Y C C+ GF + C DVNEC
Sbjct: 155 CTDGYWLLEGQCLDIDECRYG--YCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNEC 211
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
+ C NT GSF C C PGY L DG +C D+DEC C + C N
Sbjct: 212 ATENPCVQT--CVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHE----CVNQ 265
Query: 297 NGGYECSCGAGWKLV--GRRCVDRDECKELPYVC-AGGECRNFNGGYVCECP 345
G Y CSC G+ L+ R C D +EC+ + C C N GG+ C P
Sbjct: 266 PGTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDP 317
Score = 138 bits (334), Expect = 8e-32
Identities = 70/186 (37%), Positives = 94/186 (50%), Gaps = 11/186 (5%)
Query: 453 CPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTCVDVD 511
C GY + + CVD DECA D C C N +GGY C C+ G+ Q C+D+D
Sbjct: 113 CRFGYQM-DESNQCVDVDECATDSHQCNPTQICINMKGGYTCSCTDGYWLLEGQ-CLDID 170
Query: 512 ECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGS 571
EC G C C N GS+ CTC G+ + DG C+D++EC E C C N GS
Sbjct: 171 ECRYGY--CQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATE-NPCVQTCVNTYGS 227
Query: 572 YICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSED 631
+IC+C GY +D + C D++EC E LC C+N G++ C C G+ +D
Sbjct: 228 FICRCDPGYE---LEEDGVH-CSDMDECSFSEFLCQHE-CVNQPGTYFCSCPPGYILLDD 282
Query: 632 GTDCID 637
C D
Sbjct: 283 NRSCQD 288
Score = 117 bits (282), Expect = 2e-25
Identities = 94/338 (27%), Positives = 128/338 (37%), Gaps = 44/338 (13%)
Query: 207 CENLPGAYLCHCDDGFKAG-PNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCECAPGYT 264
C PG C +GF + C+D++ECR CR C N G + C
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCHSRTNPV 75
Query: 265 LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL-VGRRCVDRDECKE 323
N P+P + C G+++ +CVD DEC
Sbjct: 76 YRGPYSNPYSTPYSG--PYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECAT 133
Query: 324 LPYVCAGGE-CRNFNGGYVCECPAG-WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQ 381
+ C + C N GGY C C G W + C+D DE G C +
Sbjct: 134 DSHQCNPTQICINMKGGYTCSCTDGYWLLE---GQCLD------IDECRYGYCQQLCANV 184
Query: 382 LARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR 441
C C+ G C QD++EC + CV
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSC----------------------QDVNECATE-NPCVQ-T 220
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
CVNT GSF C C GY L DG+ C D DEC+ +C + C N G Y C C PG+
Sbjct: 221 CVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYIL 279
Query: 502 GPD-QTCVDVDECAEGRASCTFR--CHNTAGSFRCTCP 536
D ++C D++EC +C + C+N G F+C P
Sbjct: 280 LDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDP 317
Score = 111 bits (267), Expect = 1e-23
Identities = 60/172 (34%), Positives = 87/172 (50%), Gaps = 15/172 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC C+ C + P + C C+ G+ + C+DV+EC+ P C + CV
Sbjct: 169 IDECRY--GYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENP-C--VQTCV 222
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECG-DQRICDHGDCRNTIGSYRCECKPGYTLRE 186
N G+F CRC PGY L C D+DEC + +C H +C N G+Y C C PGY L +
Sbjct: 223 NTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLD 281
Query: 187 N--VCRDVDECSRPRPVCR-NGTCENLPGAYLC----HCDDGFKAGPNNDCV 231
+ C+D++EC C TC NL G + C C++ + +N C+
Sbjct: 282 DNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCM 333
Score = 110 bits (265), Expect = 2e-23
Identities = 53/111 (47%), Positives = 62/111 (55%), Gaps = 7/111 (6%)
Query: 747 DVDEC--AAIPGLCA--PGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDG 800
D+DEC LCA PG + C C PG+ G C DV+ECA P C Q C NT G
Sbjct: 168 DIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENP-CVQTCVNTYG 226
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
S+ C C GYEL+EDG +C D+DEC CQ C N G+Y CSC GY
Sbjct: 227 SFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGY 277
Score = 105 bits (252), Expect = 7e-22
Identities = 97/342 (28%), Positives = 133/342 (38%), Gaps = 47/342 (13%)
Query: 123 MAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD--CRNTIGSYRCECKP 180
+A C+ PG + +C G+ L +C D+DEC GD C N G Y C +
Sbjct: 13 LALCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCHSRT 72
Query: 181 GYTLRENVCRDVD-ECSRPRPVCRNG-TCENLPG-AYLCHCDDGFKAGPNNDCVDVNECR 237
R S P P + N P + C G++ +N CVDV+EC
Sbjct: 73 NPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECA 132
Query: 238 EGGMVCRNGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
C + C N G + C C GY L +G+ C D+DEC C C N
Sbjct: 133 TDSHQCNPTQICINMKGGYTCSCTDGYWL-LEGQ-CLDIDECRY--GYC----QQLCANV 184
Query: 297 NGGYECSCGAGWKL--VGRRCVDRDEC-KELPYVCAGGECRNFNGGYVCECPAGWRFDKT 353
G Y C+C G+ L GR C D +EC E P V C N G ++C C G+ ++
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSCQDVNECATENPCV---QTCVNTYGSFICRCDPGYELEED 241
Query: 354 AAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRI 413
C D E + E+ L + EC G +C P + R
Sbjct: 242 GVHCSD-MDECSFSEF------------LCQHECVNQPGT---YFCSCPPGYILLDDNRS 285
Query: 414 CQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECP 454
C QD++EC R C + C N G F+C P
Sbjct: 286 C----------QDINECEHRNHTCNLQQTCYNLQGGFKCIDP 317
Score = 87.8 bits (208), Expect = 1e-16
Identities = 48/123 (39%), Positives = 63/123 (51%), Gaps = 13/123 (10%)
Query: 747 DVDECAA---IPGLCAP--GRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTD 799
DV+ECA C G F C C PGY G C+D+DEC+ C C N
Sbjct: 207 DVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQP 266
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC----SCEDGYEK 853
G+Y C C GY L +D +C+D++ECE HTC QQ C N +G ++C CE+ Y +
Sbjct: 267 GTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLR 326
Query: 854 RGD 856
D
Sbjct: 327 ISD 329
Score = 78.6 bits (185), Expect = 9e-14
Identities = 45/112 (40%), Positives = 54/112 (48%), Gaps = 11/112 (9%)
Query: 752 AAIPGLCAPG----RFRCVCGPGYR-PAGEVCADVDECAVRPPPCD--QLCHNTDGSYDC 804
AA P L AP +C GY+ C DVDECA C+ Q+C N G Y C
Sbjct: 94 AAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINMKGGYTC 153
Query: 805 LCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C GY L E C D+DEC CQQ+C+N GSY C+C G+ D
Sbjct: 154 SCTDGYWLLE--GQCLDIDECRYGY--CQQLCANVPGSYSCTCNPGFTLNED 201
Score = 44.8 bits (101), Expect = 0.001
Identities = 20/64 (31%), Positives = 27/64 (42%), Gaps = 2/64 (3%)
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGY 851
LC + G+ C G++LD C D+DEC C+ +C N G Y C
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCHSRTNP 74
Query: 852 EKRG 855
RG
Sbjct: 75 VYRG 78
Score = 40.7 bits (91), Expect = 0.022
Identities = 22/57 (38%), Positives = 30/57 (52%), Gaps = 6/57 (10%)
Query: 757 LCAPGRFRCVCGPGY---RPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRT 808
L +PG + C G+ R +G+ C D+DEC P C D +C N +G Y C RT
Sbjct: 17 LPSPGNAQAQCTNGFDLDRQSGQ-CLDIDECRTIPEACRGDMMCVNQNGGYLCHSRT 72
Score = 35.5 bits (78), Expect = 0.81
Identities = 17/53 (32%), Positives = 23/53 (43%), Gaps = 2/53 (3%)
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC--PHACENVVGSYIC 574
C + G+ + C G+ + C DIDEC P C C N G Y+C
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC 68
Score = 32.3 bits (70), Expect = 7.5
Identities = 12/29 (41%), Positives = 18/29 (62%), Gaps = 1/29 (3%)
Query: 593 CEDINECEEQEDLCSGG-VCINTDGSFLC 620
C DI+EC + C G +C+N +G +LC
Sbjct: 40 CLDIDECRTIPEACRGDMMCVNQNGGYLC 68
>AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive
sequence DNA binding protein-1 protein.
Length = 1008
Score = 163 bits (396), Expect = 2e-39
Identities = 154/547 (28%), Positives = 218/547 (39%), Gaps = 70/547 (12%)
Query: 46 HTALCGEKPGEYINPVTNETKPIDECDIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTS 104
+T LC E P + + T + D C P C GTC D G+ C C G+ +
Sbjct: 24 YTCLCAE-PFKGLRCETGDHPVPDACLSAP--CHNGGTCVDADQGYVCECPEGFMGLDCR 80
Query: 105 HLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRIC- 162
R D+C CR +C+ C+CP G+ L E E C C
Sbjct: 81 E--RVPDDCE-----CRNGGRCLGANTTL-CQCPLGF--FGLLCEFEITAMPCNMNTQCP 130
Query: 163 DHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
D G C GSY C C + N + P G+C+ +Y C C GF
Sbjct: 131 DGGYCMEHGGSYLCVCHTDH----NASHSLPSPCNSDPCFNGGSCDAHDDSYTCECPRGF 186
Query: 223 KAGPNNDCVDVNECREGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDEL 281
G + + + C G CRN G C+ G + C C +T GR+C ++ + D
Sbjct: 187 H-GKHCEKARPHLCSSG--PCRNGGTCKEAGGEYHCSCPYRFT----GRHC-EIGKPDSC 238
Query: 282 PH-PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGG 339
PC G +C + G Y+C C G+ GR C + C P V GG C + +
Sbjct: 239 ASGPCHNGG--TCFHYIGKYKCDCPPGFS--GRYCEIAPSPCFRSPCV-NGGTCEDRDTD 293
Query: 340 YVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYC 399
+ C C AG+ + C E + G + L A + C
Sbjct: 294 FFCHCQAGYMGRR------------CQAEVDCGPPEEVKHATLRFNGTRLGAAALYA--C 339
Query: 400 ERCPAPDSAEFMRICQ--GGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDG 456
+R + + +R+CQ G P ++DECR +P C+ GG C + + C C G
Sbjct: 340 DRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQP--CLHGGSCQDRVAGYLCLCSTG 397
Query: 457 YVLAPDGLSC-VDADECALDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECA 514
Y +G C ++ DEC P C N G+C N G Y C+C GF +T +VD C
Sbjct: 398 Y----EGAHCELERDECRAHP--CRNGGSCRNLPGAYVCRCPAGFVGVHCET--EVDACD 449
Query: 515 EGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI-DECVQEPRVCPHACENVVGSYI 573
RC + G++ C CP G+ G HC + D C P C GS+
Sbjct: 450 SSPCQHGGRCESGGGAYLCVCPEGFF----GYHCETVSDPCFSSPCGGRGYCLASNGSHS 505
Query: 574 CKCPEGY 580
C C GY
Sbjct: 506 CTCKVGY 512
Score = 145 bits (351), Expect = 7e-34
Identities = 158/574 (27%), Positives = 223/574 (38%), Gaps = 105/574 (18%)
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR-LTPSLDECEDVDECGDQRICDHGDC 167
DVD+CS PC CV+L G + C C ++ L + D C + G C
Sbjct: 2 DVDDCS--PDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 59
Query: 168 RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN 227
+ Y CEC G+ + R D+C CRNG LC C GF
Sbjct: 60 VDADQGYVCECPEGFMGLDCRERVPDDCE-----CRNGGRCLGANTTLCQCPLGFFGLLC 114
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGR 287
+ C G C GS+ C C +T D + LP PC
Sbjct: 115 EFEITAMPCNMNTQCPDGGYCMEHGGSYLCVC---HT---------DHNASHSLPSPCNS 162
Query: 288 D---GNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRN------FNG 338
D SC + Y C C G+ G+ C K P++C+ G CRN G
Sbjct: 163 DPCFNGGSCDAHDDSYTCECPRGFH--GKHCE-----KARPHLCSSGPCRNGGTCKEAGG 215
Query: 339 GYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPL--QLARPECCCSEGAAWG 396
Y C CP +RF T C + + C +G CH + + +C C G + G
Sbjct: 216 EYHCSCP--YRF--TGRHCEIGKPDSC----ASGPCHNGGTCFHYIGKYKCDCPPGFS-G 266
Query: 397 RYCE-------RCPAPDSA-------EFMRICQGG-MGRP-------NLTQDLDECRVRP 434
RYCE R P + +F CQ G MGR +++ +R
Sbjct: 267 RYCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRF 326
Query: 435 D-VCVGGRCVNT-DGSFRCECPDGY-VLAPDGL-----SCVDADECALDPRICGNGTCSN 486
+ +G + D + P V P G+ C++ DEC P + G G+C +
Sbjct: 327 NGTRLGAAALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHG-GSCQD 385
Query: 487 TRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGV 546
GY C CS G+ + ++ DEC C N G++ C CP G+ GV
Sbjct: 386 RVAGYLCLCSTGYEGAHCE--LERDECRAHPCRNGGSCRNLPGAYVCRCPAGFV----GV 439
Query: 547 HCR-DIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENACEDINE-CEEQ 602
HC ++D C P C H CE+ G+Y+C CPEG+ CE +++ C
Sbjct: 440 HCETEVDACDSSP--CQHGGRCESGGGAYLCVCPEGF--------FGYHCETVSDPCFSS 489
Query: 603 EDLCSG-GVCINTDGSFLCDCDAGFEPSEDGTDC 635
C G G C+ ++GS C C G+ G DC
Sbjct: 490 P--CGGRGYCLASNGSHSCTCKVGY----TGEDC 517
Score = 126 bits (303), Expect = 4e-28
Identities = 146/529 (27%), Positives = 202/529 (38%), Gaps = 97/529 (18%)
Query: 152 DVDECGDQRICDHGDCRNTIGSYRCEC-KPGYTLR-ENVCRDVDECSRPRPVCRNGTCEN 209
DVD+C + G C + +G+Y C C +P LR E V + P GTC +
Sbjct: 2 DVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVD 61
Query: 210 LPGAYLCHCDDGFKAGPNNDCV-DVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTAD 268
Y+C C +GF + V D ECR GG RC + C+C G+
Sbjct: 62 ADQGYVCECPEGFMGLDCRERVPDDCECRNGG------RCLGA-NTTLCQCPLGFF---- 110
Query: 269 GRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVC 328
G C E + PC N C + GGY G + V D + LP C
Sbjct: 111 GLLC----EFEITAMPCNM--NTQCPD--GGYCMEHGGSYLCVCH--TDHNASHSLPSPC 160
Query: 329 A------GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQL 382
GG C + Y CECP G+ C R LC +G C
Sbjct: 161 NSDPCFNGGSCDAHDDSYTCECPRGFH----GKHCEKARPHLC----SSGPCRNGGT--- 209
Query: 383 ARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGR 441
C E A G Y CP + R C+ +G+P D C P C GG
Sbjct: 210 ------CKE--AGGEYHCSCPYRFTG---RHCE--IGKP------DSCASGP--CHNGGT 248
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFT 500
C + G ++C+CP G+ G C + C P + G GTC + + C C G+
Sbjct: 249 CFHYIGKYKCDCPPGF----SGRYCEIAPSPCFRSPCVNG-GTCEDRDTDFFCHCQAGYM 303
Query: 501 QGPDQTCVDVDECAEGR-ASCTFRCHNTAGSFRCTCPYGYAVAAD---------GV---- 546
Q VD E + A+ F + C GY+++A GV
Sbjct: 304 GRRCQAEVDCGPPEEVKHATLRFNGTRLGAAALYACDRGYSLSAPSRIRVCQPHGVWSEP 363
Query: 547 -HCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQED 604
C +IDEC +P + +C++ V Y+C C GY CE + +EC
Sbjct: 364 PQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAH--------CELERDEC-RAHP 414
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCE 653
+GG C N G+++C C AGF T+ + C GRCE
Sbjct: 415 CRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQH---GGRCE 460
Score = 76.6 bits (180), Expect = 4e-13
Identities = 51/159 (32%), Positives = 67/159 (42%), Gaps = 12/159 (7%)
Query: 107 CRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG 165
C ++DEC PC C + + C C GY CE + DEC + G
Sbjct: 366 CLEIDECR--SQPCLHGGSCQDRVAGYLCLCSTGYEGA----HCELERDECRAHPCRNGG 419
Query: 166 DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG 225
CRN G+Y C C G+ + + +VD C P G CE+ GAYLC C +GF
Sbjct: 420 SCRNLPGAYVCRCPAGF-VGVHCETEVDACDSS-PCQHGGRCESGGGAYLCVCPEGFFG- 476
Query: 226 PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYT 264
C V++ G C + GS C C GYT
Sbjct: 477 --YHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYT 513
Score = 60.5 bits (140), Expect = 2e-08
Identities = 42/111 (37%), Positives = 51/111 (45%), Gaps = 16/111 (14%)
Query: 757 LCAPGRFRCVCGP-GYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 815
L AP R R VC P G C ++DEC +P C + Y CLC TGYE
Sbjct: 345 LSAPSRIR-VCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYE---- 399
Query: 816 GANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGY-----EKRGDAC 858
GA+C + DEC H C+ C N G+Y C C G+ E DAC
Sbjct: 400 GAHCELERDECR--AHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDAC 448
Score = 56.8 bits (131), Expect = 3e-07
Identities = 39/117 (33%), Positives = 52/117 (44%), Gaps = 13/117 (11%)
Query: 69 DECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
DEC P C+ G +C + P + C C G+ H +VD C PC+ +C
Sbjct: 408 DECRAHP--CRNGGSCRNLPGAYVCRCPAGFVG---VHCETEVDACD--SSPCQHGGRCE 460
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDV-DECGDQRICDHGDCRNTIGSYRCECKPGYT 183
+ GA+ C CP G+ CE V D C G C + GS+ C CK GYT
Sbjct: 461 SGGGAYLCVCPEGFFGY----HCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYT 513
Score = 50.0 bits (114), Expect = 4e-05
Identities = 38/118 (32%), Positives = 52/118 (44%), Gaps = 16/118 (13%)
Query: 749 DECAAIP----GLCA--PGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGS 801
DEC A P G C PG + C C G+ G C +VD C P C + G+
Sbjct: 408 DECRAHPCRNGGSCRNLPGAYVCRCPAGF--VGVHCETEVDACDSSPCQHGGRCESGGGA 465
Query: 802 YDCLCRTGYELDEDGANCRDV-DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
Y C+C G+ G +C V D C + C + GS+ C+C+ GY G+ C
Sbjct: 466 YLCVCPEGFF----GYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGY--TGEDC 517
Score = 45.6 bits (103), Expect = 8e-04
Identities = 32/121 (26%), Positives = 50/121 (41%), Gaps = 14/121 (11%)
Query: 508 VDVDECAEGRASCTFRCHNTAGSFRCTC--PYGYAVAADGVHCRDIDECVQEPRVCPHAC 565
+DVD+C+ C + G++ C C P+ G H D C+ P C
Sbjct: 1 MDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVP-DACLSAPCHNGGTC 59
Query: 566 ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
+ Y+C+CPEG+ + + C EC +GG C+ + + LC C G
Sbjct: 60 VDADQGYVCECPEGFMGLDCRERVPDDC----ECR------NGGRCLGAN-TTLCQCPLG 108
Query: 626 F 626
F
Sbjct: 109 F 109
Score = 37.1 bits (82), Expect = 0.27
Identities = 30/104 (28%), Positives = 37/104 (35%), Gaps = 11/104 (10%)
Query: 756 GLC--APGRFRCVCGPGYRPAGEVC--ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYE 811
G C A G + C C YR G C D CA P C + G Y C C G+
Sbjct: 208 GTCKEAGGEYHCSCP--YRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGF- 264
Query: 812 LDEDGANCRDV-DECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
G C C R C + + + C C+ GY R
Sbjct: 265 ---SGRYCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGR 305
Score = 35.5 bits (78), Expect = 0.81
Identities = 24/71 (33%), Positives = 32/71 (45%), Gaps = 9/71 (12%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVCADV-DECAVRPPPCDQLCHNTD 799
+VD C + P G C G + CVC G+ G C V D C P C ++
Sbjct: 444 EVDACDSSPCQHGGRCESGGGAYLCVCPEGF--FGYHCETVSDPCFSSPCGGRGYCLASN 501
Query: 800 GSYDCLCRTGY 810
GS+ C C+ GY
Sbjct: 502 GSHSCTCKVGY 512
Score = 33.9 bits (74), Expect = 2.5
Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 13/79 (16%)
Query: 780 DVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERD---THTCQQ 834
DVD+C+ P PC C + G+Y CLC ++ G C D D + C
Sbjct: 2 DVDDCS--PDPCLNGGSCVDLVGNYTCLCAEPFK----GLRCETGDHPVPDACLSAPCHN 55
Query: 835 --ICSNTEGSYECSCEDGY 851
C + + Y C C +G+
Sbjct: 56 GGTCVDADQGYVCECPEGF 74
>AC010895-1|AAY14669.1| 320|Homo sapiens unknown protein.
Length = 320
Score = 162 bits (393), Expect = 6e-39
Identities = 78/196 (39%), Positives = 105/196 (53%), Gaps = 12/196 (6%)
Query: 427 LDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
+DEC C + C+N GSF C+CP GY G CVD DEC + P C + C
Sbjct: 1 IDECTAGTHNCRADQVCINLRGSFACQCPPGY--QKRGEQCVDIDECTIPP-YC-HQRCV 56
Query: 486 NTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
NT G + CQCSPGF + TCVD++EC + C +C+N GSF C C GY +++D
Sbjct: 57 NTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQCAQQCYNILGSFICQCNQGYELSSD 115
Query: 545 GVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED 604
++C DIDEC +C + C N G + C CP+GY+ + C+DINECE +
Sbjct: 116 RLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRS-----RTCQDINECETTNE 170
Query: 605 LCSGGVCINTDGSFLC 620
+C N G F C
Sbjct: 171 CREDEMCWNYHGGFRC 186
Score = 152 bits (369), Expect = 4e-36
Identities = 81/227 (35%), Positives = 119/227 (52%), Gaps = 21/227 (9%)
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRN 169
+DEC+ G CR C+NL G+F C+CPPGY+ ++C D+DEC C H C N
Sbjct: 1 IDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRG--EQCVDIDECTIPPYC-HQRCVN 57
Query: 170 TIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN 227
T GS+ C+C PG+ L N C D++EC + C N+ G+++C C+ G++ +
Sbjct: 58 TPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQ--CYNILGSFICQCNQGYELSSD 115
Query: 228 N-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
+C D++ECR +C+ +C N G F C C GY + R C+D++EC E + C
Sbjct: 116 RLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGYQVVR-SRTCQDINEC-ETTNECR 172
Query: 287 RDGNPSCTNTNGGYEC----SCGAGWKLV-GRRC---VDRDECKELP 325
D C N +GG+ C C + L RC V C+ELP
Sbjct: 173 ED--EMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELP 217
Score = 129 bits (312), Expect = 4e-29
Identities = 66/159 (41%), Positives = 86/159 (54%), Gaps = 9/159 (5%)
Query: 470 DECALDPRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTA 528
DEC C + C N RG + CQC PG+ + +Q CVD+DEC C RC NT
Sbjct: 2 DECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQ-CVDIDECTIP-PYCHQRCVNTP 59
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQD 588
GSF C C G+ +AA+ C DI+EC C C N++GS+IC+C +GY +S D
Sbjct: 60 GSFYCQCSPGFQLAANNYTCVDINEC-DASNQCAQQCYNILGSFICQCNQGYELSS---D 115
Query: 589 SENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
N CEDI+EC LC C+N G F C C G++
Sbjct: 116 RLN-CEDIDECRTSSYLCQYQ-CVNEPGKFSCMCPQGYQ 152
Score = 114 bits (274), Expect = 1e-24
Identities = 76/240 (31%), Positives = 111/240 (46%), Gaps = 31/240 (12%)
Query: 192 VDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRN 250
+DEC+ CR + C NL G++ C C G++ CVD++EC C RC N
Sbjct: 1 IDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR-GEQCVDIDECTIPPY-CHQ-RCVN 57
Query: 251 TVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL 310
T GSF C+C+PG+ L A+ C D++ECD + C + C N G + C C G++L
Sbjct: 58 TPGSFYCQCSPGFQLAANNYTCVDINECD-ASNQCAQ----QCYNILGSFICQCNQGYEL 112
Query: 311 VGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD--------- 359
R C D DEC+ Y+C +C N G + C CP G++ + + C D
Sbjct: 113 SSDRLNCEDIDECRTSSYLCQ-YQCVNEPGKFSCMCPQGYQVVR-SRTCQDINECETTNE 170
Query: 360 -ERKELCYDEWEAGRCHRARPLQ---LARPE--CCCSEGAAWGRYCERCPAPDSAEFMRI 413
E+C++ RC+ P Q + PE C C A C P ++M I
Sbjct: 171 CREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNA---MCRELPQSIVYKYMSI 227
Score = 109 bits (262), Expect = 4e-23
Identities = 59/182 (32%), Positives = 82/182 (45%), Gaps = 14/182 (7%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC I P C C +TP F C C G++ ++ C D++EC + QC
Sbjct: 42 IDECTI-PPYCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQ---QCY 96
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY-TLRE 186
N+ G+F C+C GY L+ CED+DEC C N G + C C GY +R
Sbjct: 97 NILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRS 156
Query: 187 NVCRDVDECSRPRPVCRNGTCENLPGAYLCH----CDDGFKAGPNNDCVDVNECREGGMV 242
C+D++EC + C N G + C+ C D + P N CV C +
Sbjct: 157 RTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCV----CPVSNAM 212
Query: 243 CR 244
CR
Sbjct: 213 CR 214
Score = 102 bits (245), Expect = 5e-21
Identities = 47/114 (41%), Positives = 59/114 (51%), Gaps = 10/114 (8%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNT 798
D+DEC IP C PG F C C PG++ A C D++EC C Q C+N
Sbjct: 41 DIDECT-IPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQCYNI 98
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
GS+ C C GYEL D NC D+DEC ++ CQ C N G + C C GY+
Sbjct: 99 LGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQ 152
Score = 102 bits (244), Expect = 6e-21
Identities = 43/96 (44%), Positives = 56/96 (58%), Gaps = 2/96 (2%)
Query: 761 GRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
G F C C PGY+ GE C D+DEC + PP C Q C NT GS+ C C G++L + C
Sbjct: 22 GSFACQCPPGYQKRGEQCVDIDECTI-PPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCV 80
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
D++EC+ ++ C Q C N GS+ C C GYE D
Sbjct: 81 DINECDA-SNQCAQQCYNILGSFICQCNQGYELSSD 115
Score = 94.7 bits (225), Expect = 1e-18
Identities = 50/130 (38%), Positives = 63/130 (48%), Gaps = 11/130 (8%)
Query: 510 VDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN 567
+DEC G +C C N GSF C CP GY G C DIDEC P C C N
Sbjct: 1 IDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQCVDIDECTIPP-YCHQRCVN 57
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
GS+ C+C G++ + + C DINEC+ C N GSF+C C+ G+E
Sbjct: 58 TPGSFYCQCSPGFQLAA----NNYTCVDINECDASNQCAQQ--CYNILGSFICQCNQGYE 111
Query: 628 PSEDGTDCID 637
S D +C D
Sbjct: 112 LSSDRLNCED 121
Score = 91.1 bits (216), Expect = 2e-17
Identities = 74/242 (30%), Positives = 101/242 (41%), Gaps = 44/242 (18%)
Query: 233 VNECREGGMVCRNGR-CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNP 291
++EC G CR + C N GSF C+C PGY G C D+DEC +P C +
Sbjct: 1 IDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQCVDIDECT-IPPYC----HQ 53
Query: 292 SCTNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWR 349
C NT G + C C G++L CVD +EC + CA +C N G ++C+C G+
Sbjct: 54 RCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQCAQ-QCYNILGSFICQCNQGYE 111
Query: 350 FDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAE 409
C D DE C + L + C +E G++ CP
Sbjct: 112 LSSDRLNCED------IDE-----CRTSSYLCQYQ---CVNEP---GKFSCMCPQGYQVV 154
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRC----ECPDGYVLAPDGLS 465
R CQ D++EC + C N G FRC C D Y+L P+
Sbjct: 155 RSRTCQ----------DINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPEN-R 203
Query: 466 CV 467
CV
Sbjct: 204 CV 205
Score = 67.7 bits (158), Expect = 2e-10
Identities = 39/119 (32%), Positives = 57/119 (47%), Gaps = 17/119 (14%)
Query: 747 DVDECAAIPGLCAP------GRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNT 798
D++EC A CA G F C C GY + + C D+DEC C C N
Sbjct: 81 DINECDA-SNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNE 139
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC----SCEDGY 851
G + C+C GY++ C+D++ECE T+ C+ ++C N G + C C+D Y
Sbjct: 140 PGKFSCMCPQGYQVVR-SRTCQDINECE-TTNECREDEMCWNYHGGFRCYPRNPCQDPY 196
Score = 64.5 bits (150), Expect = 2e-09
Identities = 30/74 (40%), Positives = 40/74 (54%), Gaps = 5/74 (6%)
Query: 781 VDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSN 838
+DEC C DQ+C N GS+ C C GY+ + G C D+DEC + C Q C N
Sbjct: 1 IDECTAGTHNCRADQVCINLRGSFACQCPPGYQ--KRGEQCVDIDECTIPPY-CHQRCVN 57
Query: 839 TEGSYECSCEDGYE 852
T GS+ C C G++
Sbjct: 58 TPGSFYCQCSPGFQ 71
Score = 53.6 bits (123), Expect = 3e-06
Identities = 20/40 (50%), Positives = 26/40 (65%), Gaps = 2/40 (5%)
Query: 822 VDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACV 859
+DEC TH C+ Q+C N GS+ C C GY+KRG+ CV
Sbjct: 1 IDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCV 40
>AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein.
Length = 1282
Score = 161 bits (392), Expect = 7e-39
Identities = 166/595 (27%), Positives = 233/595 (39%), Gaps = 85/595 (14%)
Query: 12 GAVGVPQTKYLCCCSVGHAWGAPCEA----CPPR-----GSPA-----HTALCGEKPGEY 57
G V +C C G+ GA CE C P GS +T LC E P +
Sbjct: 231 GQCQVENGSAVCVCQAGYT-GAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAE-PFKG 288
Query: 58 INPVTNETKPIDECDIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWG 116
+ T + D C P C GTC D G+ C C G+ + R D+C
Sbjct: 289 LRCETGDHPVPDACLSAP--CHNGGTCVDADQGYVCECPEGFMGLDCRE--RVPDDCE-- 342
Query: 117 RPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRIC-DHGDCRNTIGSY 174
CR +C+ C+CP G+ L E E C C D G C GSY
Sbjct: 343 ---CRNGGRCLGANTTL-CQCPLGF--FGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSY 396
Query: 175 RCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVN 234
C C + ++ D P G+C+ +Y C C GF G + + +
Sbjct: 397 LCVCHTDHNASHSLPSPCDS----DPCFNGGSCDAHDDSYTCECPRGFH-GKHCEKARPH 451
Query: 235 ECREGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPH-PCGRDGNPS 292
C G CRN G C+ G + C C +T GR+C ++ + D PC G +
Sbjct: 452 LCSSG--PCRNGGTCKEAGGEYHCSCPYRFT----GRHC-EIGKPDSCASGPCHNGG--T 502
Query: 293 CTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFD 351
C + G Y+C C G+ GR C + C P V GG C + + + C C AG+
Sbjct: 503 CFHYIGKYKCDCPPGFS--GRHCEIAPSPCFRSPCV-NGGTCEDRDTDFFCHCQAGYMGR 559
Query: 352 KTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFM 411
+ C E + G + L A + C+R + + +
Sbjct: 560 R------------CQAEVDCGPPEEVKHATLRFNGTRLGAVALYA--CDRGYSLSAPSRI 605
Query: 412 RICQ--GGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-V 467
R+CQ G P ++DECR +P C+ GG C + + C C GY +G C +
Sbjct: 606 RVCQPHGVWSEPPQCLEIDECRSQP--CLHGGSCQDRVAGYLCLCSTGY----EGAHCEL 659
Query: 468 DADECALDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHN 526
+ DEC P C N G+C N G Y C+C GF +T +VD C RC +
Sbjct: 660 ERDECRAHP--CRNGGSCRNLPGAYVCRCPAGFVGVHCET--EVDACDSSPCQHGGRCES 715
Query: 527 TAGSFRCTCPYGYAVAADGVHCRDI-DECVQEPRVCPHACENVVGSYICKCPEGY 580
G++ C CP + G HC + D C P C GS+ C C GY
Sbjct: 716 GGGAYLCVCPESFF----GYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGY 766
Score = 154 bits (373), Expect = 1e-36
Identities = 183/671 (27%), Positives = 258/671 (38%), Gaps = 136/671 (20%)
Query: 42 GSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEH 100
G+P++T C ++ T +D + Q C+ G TC F+C C G+
Sbjct: 160 GNPSYTCSC-------LSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGG 212
Query: 101 DN--TSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECG 157
T+ D EC G G Q N G+ C C GY CE DVD+C
Sbjct: 213 PTCETAQSPCDTKECQHG-----GQCQVEN--GSAVCVCQAGYTGAA----CEMDVDDCS 261
Query: 158 DQRICDHGDCRNTIGSYRCEC-KPGYTLR-ENVCRDVDECSRPRPVCRNGTCENLPGAYL 215
+ G C + +G+Y C C +P LR E V + P GTC + Y+
Sbjct: 262 PDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYV 321
Query: 216 CHCDDGFKAGPNNDCV-DVNECREGG--MVCRNGRCRNTVGSFRCECAPGYTLTADGRN- 271
C C +GF + V D ECR GG + C+ +G F C T N
Sbjct: 322 CECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNT 381
Query: 272 -CRDVDECDE------------------LPHPCGRD---GNPSCTNTNGGYECSCGAGWK 309
C D C E LP PC D SC + Y C C G+
Sbjct: 382 QCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFH 441
Query: 310 LVGRRCVDRDECKELPYVCAGGECRN------FNGGYVCECPAGWRFDKTAAVCVDERKE 363
G+ C K P++C+ G CRN G Y C CP +RF T C + +
Sbjct: 442 --GKHCE-----KARPHLCSSGPCRNGGTCKEAGGEYHCSCP--YRF--TGRHCEIGKPD 490
Query: 364 LCYDEWEAGRCHRARPL--QLARPECCCSEGAAWGRYCE-------RCPAPDSA------ 408
C +G CH + + +C C G + GR+CE R P +
Sbjct: 491 SC----ASGPCHNGGTCFHYIGKYKCDCPPGFS-GRHCEIAPSPCFRSPCVNGGTCEDRD 545
Query: 409 -EFMRICQGG-MGRP-------NLTQDLDECRVRPD----------VCVGGRCVNTDGSF 449
+F CQ G MGR +++ +R + C G ++
Sbjct: 546 TDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRI 605
Query: 450 RCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVD 509
R P G P C++ DEC P + G G+C + GY C CS G+ + ++
Sbjct: 606 RVCQPHGVWSEPP--QCLEIDECRSQPCLHG-GSCQDRVAGYLCLCSTGYEGAHCE--LE 660
Query: 510 VDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHA--CE 566
DEC C N G++ C CP G+ GVHC ++D C P C H CE
Sbjct: 661 RDECRAHPCRNGGSCRNLPGAYVCRCPAGFV----GVHCETEVDACDSSP--CQHGGRCE 714
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINE-CEEQEDLCSG-GVCINTDGSFLCDCDA 624
+ G+Y+C CPE + CE +++ C C G G C+ ++GS C C
Sbjct: 715 SGGGAYLCVCPESF--------FGYHCETVSDPCFSSP--CGGRGYCLASNGSHSCTCKV 764
Query: 625 GFEPSEDGTDC 635
G+ G DC
Sbjct: 765 GY----TGEDC 771
Score = 152 bits (368), Expect = 6e-36
Identities = 167/613 (27%), Positives = 233/613 (38%), Gaps = 89/613 (14%)
Query: 81 GTC-HDTPTG---FQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECR 136
G C D TG + C C G+ HL DV+EC+ PC+ C + +F C+
Sbjct: 151 GKCIDDCVTGNPSYTCSCLSGFT-GRRCHL--DVNECA--SQPCQNGGTCTHGINSFRCQ 205
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICDHG-DCRNTIGSYRCECKPGYTLRENVCR-DVDE 194
CP G+ P+ CE D + C HG C+ GS C C+ GYT C DVD+
Sbjct: 206 CPAGFG-GPT---CETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYT--GAACEMDVDD 259
Query: 195 CSRPRPVCRNGTCENLPGAYLCHCDDGFKA--GPNNDCVDVNECREGGMVCRNG-RCRNT 251
CS P P G+C +L G Y C C + FK D + C C NG C +
Sbjct: 260 CS-PDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAP--CHNGGTCVDA 316
Query: 252 VGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
+ CEC G+ G +CR+ +P C C N C C G+
Sbjct: 317 DQGYVCECPEGFM----GLDCRE-----RVPDDCECRNGGRCLGANTTL-CQCPLGF--F 364
Query: 312 GRRC---VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKT------AAVCVDERK 362
G C + C GG C G Y+C C + + C +
Sbjct: 365 GLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGS 424
Query: 363 ELCYDEWEAGRCHRA---RPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM- 418
+D+ C R + + ARP C S G C+ E+ C
Sbjct: 425 CDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEA----GGEYHCSCPYRFT 480
Query: 419 GRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDP 476
GR D C P C GG C + G ++C+CP G+ G C + C P
Sbjct: 481 GRHCEIGKPDSCASGP--CHNGGTCFHYIGKYKCDCPPGF----SGRHCEIAPSPCFRSP 534
Query: 477 RICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGR-ASCTFRCHNTAGSFRCTC 535
+ G GTC + + C C G+ Q VD E + A+ F C
Sbjct: 535 CVNG-GTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYAC 593
Query: 536 PYGYAVAAD---------GV-----HCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
GY+++A GV C +IDEC +P + +C++ V Y+C C GY
Sbjct: 594 DRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYE 653
Query: 582 RTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRT 640
CE + +EC +GG C N G+++C C AGF T+ +
Sbjct: 654 GAH--------CELERDEC-RAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDS 704
Query: 641 GTCYRSLVSGRCE 653
C GRCE
Sbjct: 705 SPCQH---GGRCE 714
Score = 60.5 bits (140), Expect = 2e-08
Identities = 42/111 (37%), Positives = 51/111 (45%), Gaps = 16/111 (14%)
Query: 757 LCAPGRFRCVCGP-GYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 815
L AP R R VC P G C ++DEC +P C + Y CLC TGYE
Sbjct: 599 LSAPSRIR-VCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYE---- 653
Query: 816 GANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGY-----EKRGDAC 858
GA+C + DEC H C+ C N G+Y C C G+ E DAC
Sbjct: 654 GAHCELERDECR--AHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDAC 702
Score = 54.0 bits (124), Expect = 2e-06
Identities = 37/114 (32%), Positives = 50/114 (43%), Gaps = 14/114 (12%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVCADVDE-CAVRPPPCDQLCHNTD 799
DV+ECA+ P G C G FRC C G+ G C C + C +
Sbjct: 180 DVNECASQPCQNGGTCTHGINSFRCQCPAGF--GGPTCETAQSPCDTKECQHGGQCQVEN 237
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
GS C+C+ GY GA C DVD+C D C + G+Y C C + ++
Sbjct: 238 GSAVCVCQAGYT----GAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFK 287
Score = 47.6 bits (108), Expect = 2e-04
Identities = 37/118 (31%), Positives = 51/118 (43%), Gaps = 16/118 (13%)
Query: 749 DECAAIP----GLCA--PGRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGS 801
DEC A P G C PG + C C G+ G C +VD C P C + G+
Sbjct: 662 DECRAHPCRNGGSCRNLPGAYVCRCPAGF--VGVHCETEVDACDSSPCQHGGRCESGGGA 719
Query: 802 YDCLCRTGYELDEDGANCRDV-DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
Y C+C + G +C V D C + C + GS+ C+C+ GY G+ C
Sbjct: 720 YLCVCPESFF----GYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGY--TGEDC 771
Score = 43.2 bits (97), Expect = 0.004
Identities = 34/106 (32%), Positives = 44/106 (41%), Gaps = 14/106 (13%)
Query: 758 CAPGR--FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 814
C G + C C G+ G C DV+ECA +P C + S+ C C G+
Sbjct: 157 CVTGNPSYTCSCLSGF--TGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGF---- 210
Query: 815 DGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
G C + + DT CQ C GS C C+ GY G AC
Sbjct: 211 GGPTC-ETAQSPCDTKECQHGGQCQVENGSAVCVCQAGY--TGAAC 253
Score = 42.3 bits (95), Expect = 0.007
Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 16/95 (16%)
Query: 765 CVCGPGYRPAGEVCA-DVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRD 821
CVC GY G C DVD+C+ P PC C + G+Y CLC ++ G C
Sbjct: 242 CVCQAGY--TGAACEMDVDDCS--PDPCLNGGSCVDLVGNYTCLCAEPFK----GLRCET 293
Query: 822 VDECERD---THTCQQ--ICSNTEGSYECSCEDGY 851
D D + C C + + Y C C +G+
Sbjct: 294 GDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGF 328
Score = 38.3 bits (85), Expect = 0.11
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 11/104 (10%)
Query: 756 GLC--APGRFRCVCGPGYRPAGEVC--ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYE 811
G C A G + C C YR G C D CA P C + G Y C C G+
Sbjct: 462 GTCKEAGGEYHCSCP--YRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGF- 518
Query: 812 LDEDGANCRDV-DECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
G +C C R C + + + C C+ GY R
Sbjct: 519 ---SGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGR 559
Score = 33.1 bits (72), Expect = 4.3
Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 9/71 (12%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVCADV-DECAVRPPPCDQLCHNTD 799
+VD C + P G C G + CVC + G C V D C P C ++
Sbjct: 698 EVDACDSSPCQHGGRCESGGGAYLCVCPESF--FGYHCETVSDPCFSSPCGGRGYCLASN 755
Query: 800 GSYDCLCRTGY 810
GS+ C C+ GY
Sbjct: 756 GSHSCTCKVGY 766
>AF093119-1|AAC62108.1| 439|Homo sapiens UPH1 protein.
Length = 439
Score = 157 bits (380), Expect = 2e-37
Identities = 83/207 (40%), Positives = 107/207 (51%), Gaps = 15/207 (7%)
Query: 426 DLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTC 484
D+DEC C + C N GS++C CPDGY G CVD DEC R C + C
Sbjct: 119 DVDECAQALHDCRPSQDCHNLPGSYQCTCPDGY--RKIGPECVDIDECRY--RYCQH-RC 173
Query: 485 SNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAA 543
N G + CQC PGF GP+ ++CVDV+EC G A C RC N+ G+F C C GY +
Sbjct: 174 VNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMG-APCEQRCFNSYGTFLCRCHQGYELHR 232
Query: 544 DGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEE-Q 602
DG C DIDEC +C + C N G + C CP+GY+ + C+DI+ECE
Sbjct: 233 DGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLAT-----RLCQDIDECESGA 287
Query: 603 EDLCSGGVCINTDGSFLC-DCDAGFEP 628
C+N G + C D + EP
Sbjct: 288 HQWSEAQTCVNFHGGYRCVDTNRCVEP 314
Score = 144 bits (348), Expect = 2e-33
Identities = 84/254 (33%), Positives = 118/254 (46%), Gaps = 29/254 (11%)
Query: 38 CPPRGSPAHTALCGEKPGEYINPVTNETKP-------------IDECDIMPQLCKPGT-C 83
C PR + L GE P + PV + P +DEC C+P C
Sbjct: 77 CLPRSAAVINDLHGEGPPPPVPPVNTQPLPTGYEPDDQDSCVDVDECAQALHDCRPSQDC 136
Query: 84 HDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRL 143
H+ P +QC C GY C D+DEC + C+ +CVNLPG+F C+C PG++L
Sbjct: 137 HNLPGSYQCTCPDGYRKIGPE--CVDIDECRYRY--CQH--RCVNLPGSFRCQCEPGFQL 190
Query: 144 TPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPV 201
P+ C DV+EC C+ C N+ G++ C C GY L + C D+DECS +
Sbjct: 191 GPNNRSCVDVNECDMGAPCEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYL 249
Query: 202 CRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRC--- 257
C+ C N PG + CHC G++ C D++EC G + C N G +RC
Sbjct: 250 CQY-RCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQWSEAQTCVNFHGGYRCVDT 308
Query: 258 -ECAPGYTLTADGR 270
C Y ++ R
Sbjct: 309 NRCVEPYIQVSENR 322
Score = 139 bits (336), Expect = 4e-32
Identities = 99/287 (34%), Positives = 140/287 (48%), Gaps = 35/287 (12%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C GY T++ CRDV+EC C+G +C+N G + C L S D+
Sbjct: 39 CTDGYTQ--TAN-CRDVNECLTIPEACKGEMKCINHYGGYLC-------LPRSAAVINDL 88
Query: 154 DECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCR-NGTCENLPG 212
G + + Y + ++ C DVDEC++ CR + C NLPG
Sbjct: 89 HGEGPPPPVPPVNTQPLPTGYEPD-------DQDSCVDVDECAQALHDCRPSQDCHNLPG 141
Query: 213 AYLCHCDDGF-KAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRN 271
+Y C C DG+ K GP +CVD++ECR C++ RC N GSFRC+C PG+ L + R+
Sbjct: 142 SYQCTCPDGYRKIGP--ECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRS 196
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCA 329
C DV+ECD + PC C N+ G + C C G++L G C D DEC Y+C
Sbjct: 197 CVDVNECD-MGAPC----EQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQ 251
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVC--VDERKELCYDEWEAGRC 374
C N G + C CP G++ T +C +DE + + EA C
Sbjct: 252 -YRCVNEPGRFSCHCPQGYQLLAT-RLCQDIDECESGAHQWSEAQTC 296
Score = 119 bits (286), Expect = 5e-26
Identities = 66/176 (37%), Positives = 88/176 (50%), Gaps = 13/176 (7%)
Query: 454 PDGYVLAPDGLSCVDADECALDPRIC-GNGTCSNTRGGYECQCSPGFTQ-GPDQTCVDVD 511
P GY D SCVD DECA C + C N G Y+C C G+ + GP+ CVD+D
Sbjct: 106 PTGYE-PDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE--CVDID 162
Query: 512 ECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGS 571
EC C RC N GSFRC C G+ + + C D++EC C C N G+
Sbjct: 163 ECR--YRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQRCFNSYGT 219
Query: 572 YICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
++C+C +GY +D +C DI+EC LC C+N G F C C G++
Sbjct: 220 FLCRCHQGY---ELHRDG-FSCSDIDECSYSSYLCQYR-CVNEPGRFSCHCPQGYQ 270
Score = 113 bits (273), Expect = 2e-24
Identities = 74/227 (32%), Positives = 104/227 (45%), Gaps = 29/227 (12%)
Query: 414 CQGGMGRPNLTQDLDECRVRPDVCVGG-RCVNTDGSFRCECPDGYVLAPDGLSCVDADEC 472
C G + +D++EC P+ C G +C+N G GY+ P + ++
Sbjct: 39 CTDGYTQTANCRDVNECLTIPEACKGEMKCINHYG--------GYLCLPRSAAVIND--- 87
Query: 473 ALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASC--TFRCHNTAGS 530
+ G G G+ +CVDVDECA+ C + CHN GS
Sbjct: 88 -----LHGEGPPPPVPPVNTQPLPTGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGS 142
Query: 531 FRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSE 590
++CTCP GY G C DIDEC R C H C N+ GS+ C+C G++ P +
Sbjct: 143 YQCTCPDGYRKI--GPECVDIDEC--RYRYCQHRCVNLPGSFRCQCEPGFQL--GPNN-- 194
Query: 591 NACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
+C D+NEC+ C C N+ G+FLC C G+E DG C D
Sbjct: 195 RSCVDVNECDMGAP-CEQR-CFNSYGTFLCRCHQGYELHRDGFSCSD 239
Score = 109 bits (262), Expect = 4e-23
Identities = 98/338 (28%), Positives = 132/338 (39%), Gaps = 57/338 (16%)
Query: 177 ECKPGYTLRENVCRDVDECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVDVNE 235
EC GYT N CRDV+EC C+ C N G YLC P + V +N+
Sbjct: 38 ECTDGYTQTAN-CRDVNECLTIPEACKGEMKCINHYGGYLCL--------PRSAAV-IND 87
Query: 236 CREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTN 295
G V + P D +C DVDEC + H C + C N
Sbjct: 88 LHGEGPP-------PPVPPVNTQPLPTGYEPDDQDSCVDVDECAQALHDC--RPSQDCHN 138
Query: 296 TNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAA 355
G Y+C+C G++ +G CVD DEC+ Y C N G + C+C G++
Sbjct: 139 LPGSYQCTCPDGYRKIGPECVDIDECR---YRYCQHRCVNLPGSFRCQCEPGFQLGPNNR 195
Query: 356 VCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQ 415
CVD C P + + C + ++G + RC + + +
Sbjct: 196 SCVD-----------VNECDMGAPCE----QRCFN---SYGTFLCRC-----HQGYELHR 232
Query: 416 GGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
G D+DEC +C RCVN G F C CP GY L L C D DEC
Sbjct: 233 DGFS----CSDIDECSYSSYLC-QYRCVNEPGRFSCHCPQGYQLLATRL-CQDIDECESG 286
Query: 476 PRICGNG-TCSNTRGGYEC----QCSPGFTQGPDQTCV 508
TC N GGY C +C + Q + C+
Sbjct: 287 AHQWSEAQTCVNFHGGYRCVDTNRCVEPYIQVSENRCL 324
Score = 104 bits (249), Expect = 2e-21
Identities = 47/112 (41%), Positives = 62/112 (55%), Gaps = 7/112 (6%)
Query: 747 DVDECAA--IPGLCA--PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTDG 800
D+DEC C PG FRC C PG++ P C DV+EC + P C+Q C N+ G
Sbjct: 160 DIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP-CEQRCFNSYG 218
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
++ C C GYEL DG +C D+DEC ++ CQ C N G + C C GY+
Sbjct: 219 TFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQ 270
Score = 95.9 bits (228), Expect = 5e-19
Identities = 47/122 (38%), Positives = 61/122 (50%), Gaps = 11/122 (9%)
Query: 743 DVFADVDECAAIPGLCAP--------GRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL 794
D DVDECA C P G ++C C GYR G C D+DEC R C
Sbjct: 115 DSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYR--YCQHR 172
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
C N GS+ C C G++L + +C DV+EC+ C+Q C N+ G++ C C GYE
Sbjct: 173 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGA-PCEQRCFNSYGTFLCRCHQGYELH 231
Query: 855 GD 856
D
Sbjct: 232 RD 233
Score = 69.7 bits (163), Expect = 4e-11
Identities = 45/116 (38%), Positives = 56/116 (48%), Gaps = 10/116 (8%)
Query: 747 DVDECAAIPGLCAPGRFRCVCG-PGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCL 805
DV+EC IP C G +C+ GY A +++ PP NT
Sbjct: 51 DVNECLTIPEACK-GEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPVNTQP----- 104
Query: 806 CRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACV 859
TGYE D D +C DVDEC + H C+ Q C N GSY+C+C DGY K G CV
Sbjct: 105 LPTGYEPD-DQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECV 159
Score = 66.9 bits (156), Expect = 3e-10
Identities = 40/108 (37%), Positives = 49/108 (45%), Gaps = 10/108 (9%)
Query: 747 DVDEC---AAIPGLC--APGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTD 799
DV+EC A C + G F C C GY G C+D+DEC+ C C N
Sbjct: 199 DVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEP 258
Query: 800 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC 845
G + C C GY+L C+D+DECE H Q C N G Y C
Sbjct: 259 GRFSCHCPQGYQLLATRL-CQDIDECESGAHQWSEAQTCVNFHGGYRC 305
Score = 34.3 bits (75), Expect = 1.9
Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 8/47 (17%)
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLC 620
+C +GY +T+ C D+NEC + C G + CIN G +LC
Sbjct: 38 ECTDGYTQTAN-------CRDVNECLTIPEACKGEMKCINHYGGYLC 77
>AF054501-1|AAC39881.1| 161|Homo sapiens latent transforming growth
factor-beta binding protein 4 protein.
Length = 161
Score = 154 bits (373), Expect = 1e-36
Identities = 72/148 (48%), Positives = 86/148 (58%), Gaps = 7/148 (4%)
Query: 436 VCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC-ALDPRICGNGTCSNTRGGYEC- 493
+C G C NTDGSF C CP G+ PD SC+D DEC P +CG+ C N+ G Y C
Sbjct: 1 LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV 60
Query: 494 -QCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRD 550
C PG+ GP+ TC DVDEC R+ C C N GSF+C C GY A DG HC D
Sbjct: 61 RDCDPGYHAGPEGTCDDVDEC-RNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD 119
Query: 551 IDECVQEPRVCPHA-CENVVGSYICKCP 577
++EC VC A CENV GS++C CP
Sbjct: 120 VNECETLQGVCGAALCENVEGSFLCVCP 147
Score = 133 bits (322), Expect = 2e-30
Identities = 66/151 (43%), Positives = 88/151 (58%), Gaps = 11/151 (7%)
Query: 478 ICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAE-GRASC-TFRCHNTAGSFRCT 534
+C +G C+NT G +EC C PG GPD +C+DVDEC E G A C + RC N+ GS+RC
Sbjct: 1 LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV 60
Query: 535 --CPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQDSEN 591
C GY +G C D+DEC HA C+N+ GS+ C C +GY +D +
Sbjct: 61 RDCDPGYHAGPEGT-CDDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYE---GARDGRH 116
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDC 622
C D+NECE + +C +C N +GSFLC C
Sbjct: 117 -CVDVNECETLQGVCGAALCENVEGSFLCVC 146
Score = 131 bits (316), Expect = 1e-29
Identities = 63/149 (42%), Positives = 80/149 (53%), Gaps = 8/149 (5%)
Query: 161 ICDHGDCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRP-VCRNGTCENLPGAYLC- 216
+C G C NT GS+ C C PG+ ++ C DVDEC P +C + CEN PG+Y C
Sbjct: 1 LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV 60
Query: 217 -HCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV 275
CD G+ AGP C DV+ECR + C+N GSF+C C GY DGR+C DV
Sbjct: 61 RDCDPGYHAGPEGTCDDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDV 120
Query: 276 DECDELPHPCGRDGNPSCTNTNGGYECSC 304
+EC+ L CG C N G + C C
Sbjct: 121 NECETLQGVCGA---ALCENVEGSFLCVC 146
Score = 128 bits (310), Expect = 6e-29
Identities = 66/165 (40%), Positives = 91/165 (55%), Gaps = 11/165 (6%)
Query: 201 VCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGG-MVCRNGRCRNTVGSFRC- 257
+C++G C N G++ C C G +AGP+ C+DV+ECRE G +C + RC N+ GS+RC
Sbjct: 1 LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV 60
Query: 258 -ECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRR 314
+C PGY +G C DVDEC CG + C N G ++C C G++ GR
Sbjct: 61 RDCDPGYHAGPEG-TCDDVDECRNRSF-CG--AHAVCQNLPGSFQCLCDQGYEGARDGRH 116
Query: 315 CVDRDECKELPYVCAGGECRNFNGGYVCECP-AGWRFDKTAAVCV 358
CVD +EC+ L VC C N G ++C CP + FD CV
Sbjct: 117 CVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCV 161
Score = 115 bits (277), Expect = 6e-25
Identities = 58/147 (39%), Positives = 77/147 (52%), Gaps = 6/147 (4%)
Query: 77 LCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC- 135
LC+ G C +T F+C C G+ C DVDEC P G +C N PG++ C
Sbjct: 1 LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV 60
Query: 136 -RCPPGYRLTPSLDECEDVDECGDQRICD-HGDCRNTIGSYRCECKPGYT-LRE-NVCRD 191
C PGY P C+DVDEC ++ C H C+N GS++C C GY R+ C D
Sbjct: 61 RDCDPGYHAGPE-GTCDDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD 119
Query: 192 VDECSRPRPVCRNGTCENLPGAYLCHC 218
V+EC + VC CEN+ G++LC C
Sbjct: 120 VNECETLQGVCGAALCENVEGSFLCVC 146
Score = 97.9 bits (233), Expect = 1e-19
Identities = 49/118 (41%), Positives = 62/118 (52%), Gaps = 9/118 (7%)
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQE-PRVC-PHACENVVGSYIC--KCPEG 579
C NT GSF C CP G+ D C D+DEC + P +C CEN GSY C C G
Sbjct: 7 CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPG 66
Query: 580 YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
Y + P E C+D++EC + + VC N GSF C CD G+E + DG C+D
Sbjct: 67 YH--AGP---EGTCDDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD 119
Score = 96.3 bits (229), Expect = 4e-19
Identities = 57/144 (39%), Positives = 74/144 (51%), Gaps = 12/144 (8%)
Query: 402 CPAPDSAEFMRICQGG-MGRPNLTQ--DLDECRVR-PDVCVGGRCVNTDGSFRC--ECPD 455
C D + F IC G P+L D+DECR R P +C RC N+ GS+RC +C
Sbjct: 7 CTNTDGS-FECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDP 65
Query: 456 GYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDEC 513
GY P+G +C D DEC + CG + C N G ++C C G+ D + CVDV+EC
Sbjct: 66 GYHAGPEG-TCDDVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNEC 123
Query: 514 AEGRASC-TFRCHNTAGSFRCTCP 536
+ C C N GSF C CP
Sbjct: 124 ETLQGVCGAALCENVEGSFLCVCP 147
Score = 90.6 bits (215), Expect = 2e-17
Identities = 52/120 (43%), Positives = 62/120 (51%), Gaps = 13/120 (10%)
Query: 747 DVDECAAI-PGLC-------APGRFRCV--CGPGYRPAGE-VCADVDECAVRP-PPCDQL 794
DVDEC P LC +PG +RCV C PGY E C DVDEC R +
Sbjct: 33 DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECRNRSFCGAHAV 92
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEK 853
C N GS+ CLC GYE DG +C DV+ECE C +C N EGS+ C C + E+
Sbjct: 93 CQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEE 152
Score = 89.0 bits (211), Expect = 6e-17
Identities = 49/129 (37%), Positives = 60/129 (46%), Gaps = 6/129 (4%)
Query: 54 PGEYINPVTNETKPIDEC-DIMPQLCKPGTCHDTPTGFQC--GCDHGYEHDNTSHLCRDV 110
PG P +DEC + P LC C ++P ++C CD GY H C DV
Sbjct: 20 PGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGY-HAGPEGTCDDV 78
Query: 111 DECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRICDHGDCRN 169
DEC R C A C NLPG+F+C C GY C DV+EC Q +C C N
Sbjct: 79 DECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCEN 137
Query: 170 TIGSYRCEC 178
GS+ C C
Sbjct: 138 VEGSFLCVC 146
Score = 87.0 bits (206), Expect = 3e-16
Identities = 48/115 (41%), Positives = 61/115 (53%), Gaps = 12/115 (10%)
Query: 756 GLCA--PGRFRCVCGPGYRPAGEV--CADVDECAVRPPP-C-DQLCHNTDGSYDCL--CR 807
G+C G F C+C PG+R ++ C DVDEC R P C Q C N+ GSY C+ C
Sbjct: 5 GICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCD 64
Query: 808 TGYELDEDGANCRDVDECE-RDTHTCQQICSNTEGSYECSCEDGYE--KRGDACV 859
GY +G C DVDEC R +C N GS++C C+ GYE + G CV
Sbjct: 65 PGYHAGPEGT-CDDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCV 118
Score = 84.2 bits (199), Expect = 2e-15
Identities = 45/122 (36%), Positives = 59/122 (48%), Gaps = 7/122 (5%)
Query: 242 VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDEL-PHPCGRDGNPSCTNTNGGY 300
+C++G C NT GSF C C PG+ D +C DVDEC E P CG + C N+ G Y
Sbjct: 1 LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCG---SQRCENSPGSY 57
Query: 301 EC--SCGAGWKLVGR-RCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVC 357
C C G+ C D DEC+ + A C+N G + C C G+ + C
Sbjct: 58 RCVRDCDPGYHAGPEGTCDDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC 117
Query: 358 VD 359
VD
Sbjct: 118 VD 119
Score = 81.8 bits (193), Expect = 9e-15
Identities = 59/171 (34%), Positives = 71/171 (41%), Gaps = 27/171 (15%)
Query: 327 VCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPE 386
+C G C N +G + C CP G R A C+D DE C R R P
Sbjct: 1 LCQSGICTNTDGSFECICPPGHRAGPDLASCLD------VDE-----C-RERG-----PA 43
Query: 387 CCCSEGAAWGRYCERCPAPDSAEFMRICQGGM--GRPNLTQDLDECRVRPDVCVGGRCVN 444
C S+ CE +P S +R C G G D+DECR R C N
Sbjct: 44 LCGSQR------CEN--SPGSYRCVRDCDPGYHAGPEGTCDDVDECRNRSFCGAHAVCQN 95
Query: 445 TDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQC 495
GSF+C C GY A DG CVD +EC +CG C N G + C C
Sbjct: 96 LPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVC 146
Score = 58.8 bits (136), Expect = 8e-08
Identities = 31/85 (36%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 54 PGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDEC 113
PG + P +DEC C + P FQC CD GYE C DV+EC
Sbjct: 65 PGYHAGP-EGTCDDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNEC 123
Query: 114 SWGRPPCRGMAQCVNLPGAFECRCP 138
+ C G A C N+ G+F C CP
Sbjct: 124 ETLQGVC-GAALCENVEGSFLCVCP 147
Score = 57.6 bits (133), Expect = 2e-07
Identities = 47/168 (27%), Positives = 63/168 (37%), Gaps = 31/168 (18%)
Query: 293 CTNTNGGYECSCGAGWKLVG--RRCVDRDECKEL-PYVCAGGECRNFNGGYVC--ECPAG 347
CTNT+G +EC C G + C+D DEC+E P +C C N G Y C +C G
Sbjct: 7 CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPG 66
Query: 348 WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS 407
+ C D + C + G H +C C +G R C
Sbjct: 67 YHAGPEGT-CDDVDE--CRNRSFCG-AHAVCQNLPGSFQCLCDQGYEGARDGRHCV---- 118
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPD 455
D++EC VC C N +GSF C CP+
Sbjct: 119 ------------------DVNECETLQGVCGAALCENVEGSFLCVCPN 148
Score = 42.3 bits (95), Expect = 0.007
Identities = 16/33 (48%), Positives = 18/33 (54%)
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
LC G+C NTDGSF C C G D C+D
Sbjct: 1 LCQSGICTNTDGSFECICPPGHRAGPDLASCLD 33
Score = 32.7 bits (71), Expect = 5.7
Identities = 13/26 (50%), Positives = 17/26 (65%), Gaps = 1/26 (3%)
Query: 832 CQQ-ICSNTEGSYECSCEDGYEKRGD 856
CQ IC+NT+GS+EC C G+ D
Sbjct: 2 CQSGICTNTDGSFECICPPGHRAGPD 27
>AL133553-4|CAI17860.1| 240|Homo sapiens protein ( Human DNA
sequence from clone GS1-174L6 on chromosome 1. ).
Length = 240
Score = 153 bits (372), Expect = 2e-36
Identities = 77/180 (42%), Positives = 98/180 (54%), Gaps = 15/180 (8%)
Query: 447 GSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NGTCSNTRGGYEC--QCSPGFTQGP 503
GSF C C GY L G C+D +EC + +C + C NTRGGY+C C G T+
Sbjct: 3 GSFHCGCEPGYQLK--GRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNGMTKAE 58
Query: 504 DQTCVDVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVC 561
+ TC+D+DEC +G C + C NT GS+RC CP GY G C DIDEC + C
Sbjct: 59 NGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDEC-ENTDAC 117
Query: 562 PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCS-GGVCINTDGSFLC 620
H C+N GSY C CP GY+ T + C+DI+EC EQ C +C N GS+ C
Sbjct: 118 QHECKNTFGSYQCICPPGYQLT----HNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 173
Score = 146 bits (353), Expect = 4e-34
Identities = 78/198 (39%), Positives = 102/198 (51%), Gaps = 17/198 (8%)
Query: 171 IGSYRCECKPGYTLRENVCRDVDECSRPRPVCR-NGTCENLPGAYLC--HCDDGFKAGPN 227
IGS+ C C+PGY L+ C DV+EC + VCR + C+N G Y C C +G N
Sbjct: 2 IGSFHCGCEPGYQLKGRKCMDVNECR--QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAEN 59
Query: 228 NDCVDVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCG 286
C+D++EC++G CR N C NT GS+RC C GY GR C D+DEC E C
Sbjct: 60 GTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDEC-ENTDACQ 118
Query: 287 RDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGE-CRNFNGGYVC- 342
+ C NT G Y+C C G++L G+ C D DEC E C C N G Y C
Sbjct: 119 HE----CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCI 174
Query: 343 --ECPAGWRFDKTAAVCV 358
CP ++ D + C+
Sbjct: 175 DTPCPPNYQRDPVSGFCL 192
Score = 145 bits (351), Expect = 7e-34
Identities = 76/178 (42%), Positives = 101/178 (56%), Gaps = 13/178 (7%)
Query: 131 GAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD-CRNTIGSYRCE--CKPGYTLREN 187
G+F C C PGY+L +C DV+EC Q +C C+NT G Y+C C G T EN
Sbjct: 3 GSFHCGCEPGYQLKGR--KCMDVNECR-QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAEN 59
Query: 188 -VCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCR 244
C D+DEC CR N CEN G+Y C C G+++ G C+D++EC E C+
Sbjct: 60 GTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDEC-ENTDACQ 118
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC 302
+ C+NT GS++C C PGY LT +G+ C+D+DEC E CG N C N G Y+C
Sbjct: 119 H-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCG--PNRMCFNMRGSYQC 173
Score = 130 bits (315), Expect = 2e-29
Identities = 70/167 (41%), Positives = 97/167 (58%), Gaps = 14/167 (8%)
Query: 426 DLDECRVRPDVCVGGR-CVNTDGSFRCE--CPDGYVLAPDGLSCVDADECALDPRICG-N 481
D++ECR +VC + C NT G ++C CP+G A +G +C+D DEC C N
Sbjct: 22 DVNECR--QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG-TCIDIDECKDGTHQCRYN 78
Query: 482 GTCSNTRGGYECQCSPGF-TQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA 540
C NTRG Y C C G+ +QG + C+D+DEC E +C C NT GS++C CP GY
Sbjct: 79 QICENTRGSYRCVCPRGYRSQGVGRPCMDIDEC-ENTDACQHECKNTFGSYQCICPPGYQ 137
Query: 541 VAADGVHCRDIDECVQEPRVC-PH-ACENVVGSYIC---KCPEGYRR 582
+ +G C+DIDEC+++ C P+ C N+ GSY C CP Y+R
Sbjct: 138 LTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 184
Score = 116 bits (279), Expect = 4e-25
Identities = 63/173 (36%), Positives = 86/173 (49%), Gaps = 12/173 (6%)
Query: 50 CGEKPGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCG--CDHGYEHDNTSHL 106
CG +PG + + ++EC +C+P C +T G++C C +G
Sbjct: 7 CGCEPGYQLKG--RKCMDVNEC--RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG-T 61
Query: 107 CRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD 166
C D+DEC G CR C N G++ C CP GYR C D+DEC + C H +
Sbjct: 62 CIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECENTDACQH-E 120
Query: 167 CRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVC-RNGTCENLPGAYLC 216
C+NT GSY+C C PGY L N C+D+DEC C N C N+ G+Y C
Sbjct: 121 CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 173
Score = 110 bits (264), Expect = 2e-23
Identities = 57/152 (37%), Positives = 79/152 (51%), Gaps = 11/152 (7%)
Query: 212 GAYLCHCDDGFKAGPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRC-ECAPGYTLTADG 269
G++ C C+ G++ C+DVNECR+ VCR + C+NT G ++C + P A+
Sbjct: 3 GSFHCGCEPGYQL-KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNGMTKAEN 59
Query: 270 RNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYV 327
C D+DEC + H C N C NT G Y C C G++ VGR C+D DEC+
Sbjct: 60 GTCIDIDECKDGTHQCRY--NQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECENTD-A 116
Query: 328 CAGGECRNFNGGYVCECPAGWRFDKTAAVCVD 359
C EC+N G Y C CP G++ C D
Sbjct: 117 CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQD 147
Score = 108 bits (260), Expect = 7e-23
Identities = 67/185 (36%), Positives = 89/185 (48%), Gaps = 18/185 (9%)
Query: 90 FQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC--RCPPGYRLTPSL 147
F CGC+ GY+ C DV+EC + CR C N G ++C CP G +
Sbjct: 5 FHCGCEPGYQLKGRK--CMDVNECR--QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAEN- 59
Query: 148 DECEDVDECGD-QRICDHGD-CRNTIGSYRCECKPGYTLR--ENVCRDVDECSRPRPVCR 203
C D+DEC D C + C NT GSYRC C GY + C D+DEC C+
Sbjct: 60 GTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECEN-TDACQ 118
Query: 204 NGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVC-RNGRCRNTVGSFRC---E 258
+ C+N G+Y C C G++ N C D++EC E + C N C N GS++C
Sbjct: 119 H-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTP 177
Query: 259 CAPGY 263
C P Y
Sbjct: 178 CPPNY 182
Score = 108 bits (259), Expect = 9e-23
Identities = 60/153 (39%), Positives = 76/153 (49%), Gaps = 12/153 (7%)
Query: 489 GGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCT--CPYGYAVAADGV 546
G + C C PG+ Q + C+DV+EC + C NT G ++C CP G A +G
Sbjct: 3 GSFHCGCEPGY-QLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGT 61
Query: 547 HCRDIDECVQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQED 604
C DIDEC C + CEN GSY C CP GYR Q C DI+ECE D
Sbjct: 62 -CIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRS----QGVGRPCMDIDECENT-D 115
Query: 605 LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C C NT GS+ C C G++ + +G C D
Sbjct: 116 ACQHE-CKNTFGSYQCICPPGYQLTHNGKTCQD 147
Score = 97.5 bits (232), Expect = 2e-19
Identities = 48/101 (47%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Query: 759 APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDC--LCRTGYELDEDG 816
A G F C C PGY+ G C DV+EC DQ C NT G Y C LC G E+G
Sbjct: 1 AIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 60
Query: 817 ANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRG 855
C D+DEC+ TH C+ QIC NT GSY C C GY +G
Sbjct: 61 -TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQG 100
Score = 89.8 bits (213), Expect = 4e-17
Identities = 42/100 (42%), Positives = 56/100 (56%), Gaps = 8/100 (8%)
Query: 761 GRFRCVCGPGYRP--AGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
G +RCVC GYR G C D+DEC C C NT GSY C+C GY+L +G
Sbjct: 86 GSYRCVCPRGYRSQGVGRPCMDIDECE-NTDACQHECKNTFGSYQCICPPGYQLTHNGKT 144
Query: 819 CRDVDEC-ERDTHT-CQQICSNTEGSYEC---SCEDGYEK 853
C+D+DEC E++ H ++C N GSY+C C Y++
Sbjct: 145 CQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR 184
Score = 88.2 bits (209), Expect = 1e-16
Identities = 48/119 (40%), Positives = 61/119 (51%), Gaps = 16/119 (13%)
Query: 747 DVDECAAIPGLCAP--------GRFRCV--CGPGYRPAGE-VCADVDECAVRPPPC--DQ 793
DV+EC +C P G ++C+ C G A C D+DEC C +Q
Sbjct: 22 DVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQ 79
Query: 794 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE 852
+C NT GSY C+C GY G C D+DECE +T CQ C NT GSY+C C GY+
Sbjct: 80 ICENTRGSYRCVCPRGYRSQGVGRPCMDIDECE-NTDACQHECKNTFGSYQCICPPGYQ 137
Score = 39.5 bits (88), Expect = 0.050
Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 12/72 (16%)
Query: 569 VGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CINTDGSFLCD--CDAG 625
+GS+ C C GY Q C D+NEC ++++C C NT G + C C G
Sbjct: 2 IGSFHCGCEPGY------QLKGRKCMDVNEC--RQNVCRPDQHCKNTRGGYKCIDLCPNG 53
Query: 626 FEPSEDGTDCID 637
+E+GT CID
Sbjct: 54 MTKAENGT-CID 64
>AK222891-1|BAD96611.1| 810|Homo sapiens egf-like module
containing, mucin-like, hormone receptor-like sequence 2
isofor protein.
Length = 810
Score = 153 bits (372), Expect = 2e-36
Identities = 88/218 (40%), Positives = 111/218 (50%), Gaps = 33/218 (15%)
Query: 120 CRGMAQCVNLPGAFECRCPPGYR-----LTPSLDECEDVDECGDQRICDHG---DCRNTI 171
C + CVN A CRC PG+ +T ++ C+D++EC G DC NT
Sbjct: 33 CPQDSSCVN---ATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTE 89
Query: 172 GSYRCECKPGY-------TLR---ENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDD 220
GSY C C PGY T + EN C+DVDEC + +C++ GTC N G+Y C C
Sbjct: 90 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 149
Query: 221 GFKAGPNND--CVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTL---TADGRN--- 271
GFK P + C DVNEC G C + C N VGS++C C PG+ + +G N
Sbjct: 150 GFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTV 209
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
C DVDEC H C D + C NT G Y C C GWK
Sbjct: 210 CEDVDECSSGQHQC--DSSTVCFNTVGSYSCRCRPGWK 245
Score = 122 bits (294), Expect = 5e-27
Identities = 70/196 (35%), Positives = 95/196 (48%), Gaps = 25/196 (12%)
Query: 426 DLDECRVRPDVCVG--GRCVNTDGSFRCECPDGYVLAPDGLS--------CVDADECALD 475
D++EC V G C NT+GS+ C C GY + C D DEC +
Sbjct: 67 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 126
Query: 476 PRICGN-GTCSNTRGGYECQCSPGFTQGPD--QTCVDVDECAEGRASC--TFRCHNTAGS 530
PR+C + GTC NT G Y CQC PGF P+ + C DV+EC G+ C + C N GS
Sbjct: 127 PRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGS 186
Query: 531 FRCTCPYGYAV------AADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYR- 581
++C C G+ + C D+DEC C + C N VGSY C+C G++
Sbjct: 187 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 246
Query: 582 RTSAPQD-SENACEDI 596
R P + + CED+
Sbjct: 247 RHGIPNNQKDTVCEDM 262
Score = 120 bits (289), Expect = 2e-26
Identities = 73/211 (34%), Positives = 99/211 (46%), Gaps = 27/211 (12%)
Query: 442 CVNTDGSFRCECPDGY-----VLAPDGLSCVDADECALDPRI-CGN-GTCSNTRGGYECQ 494
CVN C C G+ ++ +C D +ECA ++ CG C NT G Y+C
Sbjct: 39 CVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCV 95
Query: 495 CSPG---------FTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFRCTCPYGYAVAA 543
CSPG F + TC DVDEC + C C NT GS+ C C G+ +
Sbjct: 96 CSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKP 155
Query: 544 -DGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSEN--ACEDINE 598
D C D++EC C + C N VGSY C+C G++ + N CED++E
Sbjct: 156 EDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDE 215
Query: 599 CEEQEDLC-SGGVCINTDGSFLCDCDAGFEP 628
C + C S VC NT GS+ C C G++P
Sbjct: 216 CSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 246
Score = 118 bits (283), Expect = 1e-25
Identities = 74/233 (31%), Positives = 104/233 (44%), Gaps = 33/233 (14%)
Query: 146 SLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY-------TLRENVCRDVDECSRP 198
+L E D G R C + + + C C PG+ T C D++EC+
Sbjct: 17 TLPGAETQDSRGCARWCPQDS--SCVNATACRCNPGFSSFSEIITTPMETCDDINECATL 74
Query: 199 RPV-C-RNGTCENLPGAYLCHCDDG---------FKAGPNNDCVDVNECREGGMVCRN-G 246
V C + C N G+Y C C G FK N C DV+EC++ +C++ G
Sbjct: 75 SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYG 134
Query: 247 RCRNTVGSFRCECAPGYTL-TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C NT+GS+ C+C PG+ L D + C DV+EC +PC + C N G Y+C C
Sbjct: 135 TCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPC--HSSTHCLNNVGSYQCRCR 192
Query: 306 AGWKLV--------GRRCVDRDECKELPYVC-AGGECRNFNGGYVCECPAGWR 349
GW+ + C D DEC + C + C N G Y C C GW+
Sbjct: 193 PGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245
Score = 116 bits (278), Expect = 5e-25
Identities = 67/198 (33%), Positives = 96/198 (48%), Gaps = 19/198 (9%)
Query: 1 MEWNEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
ME ++ CA V K+ C + ++ C SP + + G K + N
Sbjct: 62 METCDDINECATLSKVSCGKFSDCWNTEGSYDCVC-------SPGYEPVSGAKT--FKNE 112
Query: 61 VTNETKPIDECDIMPQLCKP-GTCHDTPTGFQCGCDHGYE-HDNTSHLCRDVDECSWGRP 118
N + +DEC P+LCK GTC +T + C C G++ LC DV+EC+ G+
Sbjct: 113 SENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQN 172
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDE------CEDVDECGD-QRICDHGD-CRNT 170
PC C+N G+++CRC PG++ P CEDVDEC Q CD C NT
Sbjct: 173 PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNT 232
Query: 171 IGSYRCECKPGYTLRENV 188
+GSY C C+PG+ R +
Sbjct: 233 VGSYSCRCRPGWKPRHGI 250
Score = 104 bits (250), Expect = 1e-21
Identities = 54/130 (41%), Positives = 71/130 (54%), Gaps = 12/130 (9%)
Query: 422 NLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAP-DGLSCVDADECALDPRIC 479
N QD+DEC+ P +C G CVNT GS+ C+C G+ L P D C D +EC C
Sbjct: 115 NTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPC 174
Query: 480 GNGT-CSNTRGGYECQCSPGF------TQGPDQT-CVDVDECAEGRASC--TFRCHNTAG 529
+ T C N G Y+C+C PG+ GP+ T C DVDEC+ G+ C + C NT G
Sbjct: 175 HSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVG 234
Query: 530 SFRCTCPYGY 539
S+ C C G+
Sbjct: 235 SYSCRCRPGW 244
Score = 86.2 bits (204), Expect = 4e-16
Identities = 50/129 (38%), Positives = 61/129 (47%), Gaps = 21/129 (16%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYRPAGE---VCADVDECAVRPPPCDQLC 795
DVDEC P LC G + C C PG++ E +C DV+EC PC
Sbjct: 119 DVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSST 178
Query: 796 H--NTDGSYDCLCRTGYEL---DEDGAN---CRDVDECERDTHTCQQ--ICSNTEGSYEC 845
H N GSY C CR G++ +G N C DVDEC H C +C NT GSY C
Sbjct: 179 HCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSC 238
Query: 846 SCEDGYEKR 854
C G++ R
Sbjct: 239 RCRPGWKPR 247
Score = 78.6 bits (185), Expect = 9e-14
Identities = 42/107 (39%), Positives = 50/107 (46%), Gaps = 15/107 (14%)
Query: 761 GRFRCVCGPGYRPAG----------EVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRT 808
G + CVC PGY P C DVDEC P C C NT GSY C C
Sbjct: 90 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 149
Query: 809 GYEL-DEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE 852
G++L ED C DV+EC + C C N GSY+C C G++
Sbjct: 150 GFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 196
Score = 74.1 bits (174), Expect = 2e-12
Identities = 40/108 (37%), Positives = 56/108 (51%), Gaps = 20/108 (18%)
Query: 765 CVCGPGYRPAGEV-------CADVDECA-VRPPPCDQL--CHNTDGSYDCLCRTGYE--- 811
C C PG+ E+ C D++ECA + C + C NT+GSYDC+C GYE
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 812 -----LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE 852
+E C+DVDEC+++ C+ C NT GSY C C G++
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 152
Score = 73.7 bits (173), Expect = 2e-12
Identities = 41/99 (41%), Positives = 53/99 (53%), Gaps = 9/99 (9%)
Query: 548 CRDIDECVQEPRV-CPHA--CENVVGSYICKCPEGYRRTSAPQ----DSENACEDINECE 600
C DI+EC +V C C N GSY C C GY S + +SEN C+D++EC+
Sbjct: 65 CDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQ 124
Query: 601 EQEDLC-SGGVCINTDGSFLCDCDAGFE-PSEDGTDCID 637
+ LC S G C+NT GS+ C C GF+ ED C D
Sbjct: 125 QNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTD 163
Score = 71.7 bits (168), Expect = 1e-11
Identities = 67/252 (26%), Positives = 92/252 (36%), Gaps = 40/252 (15%)
Query: 265 LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR-------RCVD 317
LT G +D C C +D SC N C C G+ C D
Sbjct: 16 LTLPGAETQDSRGCARW---CPQDS--SCVNATA---CRCNPGFSSFSEIITTPMETCDD 67
Query: 318 RDECKELPYVCAG--GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCH 375
+EC L V G +C N G Y C C G+ A +E + C D C
Sbjct: 68 INECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQD---VDECQ 124
Query: 376 RARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPD 435
+ P C S G C + + + + P L D++EC +
Sbjct: 125 Q-------NPRLCKSYGT-----CVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQN 172
Query: 436 VCVGG-RCVNTDGSFRCECPDGY------VLAPDGLSCVDADECALDPRICGNGT-CSNT 487
C C+N GS++C C G+ P+ C D DEC+ C + T C NT
Sbjct: 173 PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNT 232
Query: 488 RGGYECQCSPGF 499
G Y C+C PG+
Sbjct: 233 VGSYSCRCRPGW 244
Score = 47.2 bits (107), Expect = 2e-04
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 6/94 (6%)
Query: 556 QEPRVCPHAC---ENVVGSYICKCPEGYRRTSAPQDSE-NACEDINECEEQEDLCSGGV- 610
Q+ R C C + V + C+C G+ S + C+DINEC + G
Sbjct: 24 QDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFS 83
Query: 611 -CINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
C NT+GS+ C C G+EP + TC
Sbjct: 84 DCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTC 117
Score = 34.3 bits (75), Expect = 1.9
Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 7/73 (9%)
Query: 54 PGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCD------HGYEHDNTSHL 106
PG P + +DEC C T C +T + C C HG ++ +
Sbjct: 199 PGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTV 258
Query: 107 CRDVDECSWGRPP 119
C D+ +W PP
Sbjct: 259 CEDMTFSTWTPPP 271
>AF114491-1|AAF21974.1| 823|Homo sapiens EGF-like module EMR2
protein.
Length = 823
Score = 153 bits (372), Expect = 2e-36
Identities = 88/218 (40%), Positives = 111/218 (50%), Gaps = 33/218 (15%)
Query: 120 CRGMAQCVNLPGAFECRCPPGYR-----LTPSLDECEDVDECGDQRICDHG---DCRNTI 171
C + CVN A CRC PG+ +T ++ C+D++EC G DC NT
Sbjct: 33 CPQDSSCVN---ATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTE 89
Query: 172 GSYRCECKPGY-------TLR---ENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDD 220
GSY C C PGY T + EN C+DVDEC + +C++ GTC N G+Y C C
Sbjct: 90 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 149
Query: 221 GFKAGPNND--CVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTL---TADGRN--- 271
GFK P + C DVNEC G C + C N VGS++C C PG+ + +G N
Sbjct: 150 GFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTV 209
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
C DVDEC H C D + C NT G Y C C GWK
Sbjct: 210 CEDVDECSSGQHQC--DSSTVCFNTVGSYSCRCRPGWK 245
Score = 122 bits (294), Expect = 5e-27
Identities = 70/196 (35%), Positives = 95/196 (48%), Gaps = 25/196 (12%)
Query: 426 DLDECRVRPDVCVG--GRCVNTDGSFRCECPDGYVLAPDGLS--------CVDADECALD 475
D++EC V G C NT+GS+ C C GY + C D DEC +
Sbjct: 67 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 126
Query: 476 PRICGN-GTCSNTRGGYECQCSPGFTQGPD--QTCVDVDECAEGRASC--TFRCHNTAGS 530
PR+C + GTC NT G Y CQC PGF P+ + C DV+EC G+ C + C N GS
Sbjct: 127 PRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGS 186
Query: 531 FRCTCPYGYAV------AADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYR- 581
++C C G+ + C D+DEC C + C N VGSY C+C G++
Sbjct: 187 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 246
Query: 582 RTSAPQD-SENACEDI 596
R P + + CED+
Sbjct: 247 RHGIPNNQKDTVCEDM 262
Score = 120 bits (289), Expect = 2e-26
Identities = 73/211 (34%), Positives = 99/211 (46%), Gaps = 27/211 (12%)
Query: 442 CVNTDGSFRCECPDGY-----VLAPDGLSCVDADECALDPRI-CGN-GTCSNTRGGYECQ 494
CVN C C G+ ++ +C D +ECA ++ CG C NT G Y+C
Sbjct: 39 CVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCV 95
Query: 495 CSPG---------FTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFRCTCPYGYAVAA 543
CSPG F + TC DVDEC + C C NT GS+ C C G+ +
Sbjct: 96 CSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKP 155
Query: 544 -DGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSEN--ACEDINE 598
D C D++EC C + C N VGSY C+C G++ + N CED++E
Sbjct: 156 EDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDE 215
Query: 599 CEEQEDLC-SGGVCINTDGSFLCDCDAGFEP 628
C + C S VC NT GS+ C C G++P
Sbjct: 216 CSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 246
Score = 118 bits (283), Expect = 1e-25
Identities = 74/233 (31%), Positives = 104/233 (44%), Gaps = 33/233 (14%)
Query: 146 SLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY-------TLRENVCRDVDECSRP 198
+L E D G R C + + + C C PG+ T C D++EC+
Sbjct: 17 TLPGAETQDSRGCARWCPQDS--SCVNATACRCNPGFSSFSEIITTPMETCDDINECATL 74
Query: 199 RPV-C-RNGTCENLPGAYLCHCDDG---------FKAGPNNDCVDVNECREGGMVCRN-G 246
V C + C N G+Y C C G FK N C DV+EC++ +C++ G
Sbjct: 75 SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYG 134
Query: 247 RCRNTVGSFRCECAPGYTL-TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C NT+GS+ C+C PG+ L D + C DV+EC +PC + C N G Y+C C
Sbjct: 135 TCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPC--HSSTHCLNNVGSYQCRCR 192
Query: 306 AGWKLV--------GRRCVDRDECKELPYVC-AGGECRNFNGGYVCECPAGWR 349
GW+ + C D DEC + C + C N G Y C C GW+
Sbjct: 193 PGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245
Score = 116 bits (278), Expect = 5e-25
Identities = 67/198 (33%), Positives = 96/198 (48%), Gaps = 19/198 (9%)
Query: 1 MEWNEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
ME ++ CA V K+ C + ++ C SP + + G K + N
Sbjct: 62 METCDDINECATLSKVSCGKFSDCWNTEGSYDCVC-------SPGYEPVSGAKT--FKNE 112
Query: 61 VTNETKPIDECDIMPQLCKP-GTCHDTPTGFQCGCDHGYE-HDNTSHLCRDVDECSWGRP 118
N + +DEC P+LCK GTC +T + C C G++ LC DV+EC+ G+
Sbjct: 113 SENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQN 172
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDE------CEDVDECGD-QRICDHGD-CRNT 170
PC C+N G+++CRC PG++ P CEDVDEC Q CD C NT
Sbjct: 173 PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNT 232
Query: 171 IGSYRCECKPGYTLRENV 188
+GSY C C+PG+ R +
Sbjct: 233 VGSYSCRCRPGWKPRHGI 250
Score = 104 bits (250), Expect = 1e-21
Identities = 54/130 (41%), Positives = 71/130 (54%), Gaps = 12/130 (9%)
Query: 422 NLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAP-DGLSCVDADECALDPRIC 479
N QD+DEC+ P +C G CVNT GS+ C+C G+ L P D C D +EC C
Sbjct: 115 NTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPC 174
Query: 480 GNGT-CSNTRGGYECQCSPGF------TQGPDQT-CVDVDECAEGRASC--TFRCHNTAG 529
+ T C N G Y+C+C PG+ GP+ T C DVDEC+ G+ C + C NT G
Sbjct: 175 HSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVG 234
Query: 530 SFRCTCPYGY 539
S+ C C G+
Sbjct: 235 SYSCRCRPGW 244
Score = 86.2 bits (204), Expect = 4e-16
Identities = 50/129 (38%), Positives = 61/129 (47%), Gaps = 21/129 (16%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYRPAGE---VCADVDECAVRPPPCDQLC 795
DVDEC P LC G + C C PG++ E +C DV+EC PC
Sbjct: 119 DVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSST 178
Query: 796 H--NTDGSYDCLCRTGYEL---DEDGAN---CRDVDECERDTHTCQQ--ICSNTEGSYEC 845
H N GSY C CR G++ +G N C DVDEC H C +C NT GSY C
Sbjct: 179 HCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSC 238
Query: 846 SCEDGYEKR 854
C G++ R
Sbjct: 239 RCRPGWKPR 247
Score = 78.6 bits (185), Expect = 9e-14
Identities = 42/107 (39%), Positives = 50/107 (46%), Gaps = 15/107 (14%)
Query: 761 GRFRCVCGPGYRPAG----------EVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRT 808
G + CVC PGY P C DVDEC P C C NT GSY C C
Sbjct: 90 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 149
Query: 809 GYEL-DEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE 852
G++L ED C DV+EC + C C N GSY+C C G++
Sbjct: 150 GFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 196
Score = 74.1 bits (174), Expect = 2e-12
Identities = 40/108 (37%), Positives = 56/108 (51%), Gaps = 20/108 (18%)
Query: 765 CVCGPGYRPAGEV-------CADVDECA-VRPPPCDQL--CHNTDGSYDCLCRTGYE--- 811
C C PG+ E+ C D++ECA + C + C NT+GSYDC+C GYE
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 812 -----LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE 852
+E C+DVDEC+++ C+ C NT GSY C C G++
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 152
Score = 73.7 bits (173), Expect = 2e-12
Identities = 41/99 (41%), Positives = 53/99 (53%), Gaps = 9/99 (9%)
Query: 548 CRDIDECVQEPRV-CPHA--CENVVGSYICKCPEGYRRTSAPQ----DSENACEDINECE 600
C DI+EC +V C C N GSY C C GY S + +SEN C+D++EC+
Sbjct: 65 CDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQ 124
Query: 601 EQEDLC-SGGVCINTDGSFLCDCDAGFE-PSEDGTDCID 637
+ LC S G C+NT GS+ C C GF+ ED C D
Sbjct: 125 QNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTD 163
Score = 71.7 bits (168), Expect = 1e-11
Identities = 67/252 (26%), Positives = 92/252 (36%), Gaps = 40/252 (15%)
Query: 265 LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR-------RCVD 317
LT G +D C C +D SC N C C G+ C D
Sbjct: 16 LTLPGAETQDSRGCARW---CPQDS--SCVNATA---CRCNPGFSSFSEIITTPMETCDD 67
Query: 318 RDECKELPYVCAG--GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCH 375
+EC L V G +C N G Y C C G+ A +E + C D C
Sbjct: 68 INECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQD---VDECQ 124
Query: 376 RARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPD 435
+ P C S G C + + + + P L D++EC +
Sbjct: 125 Q-------NPRLCKSYGT-----CVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQN 172
Query: 436 VCVGG-RCVNTDGSFRCECPDGY------VLAPDGLSCVDADECALDPRICGNGT-CSNT 487
C C+N GS++C C G+ P+ C D DEC+ C + T C NT
Sbjct: 173 PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNT 232
Query: 488 RGGYECQCSPGF 499
G Y C+C PG+
Sbjct: 233 VGSYSCRCRPGW 244
Score = 47.2 bits (107), Expect = 2e-04
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 6/94 (6%)
Query: 556 QEPRVCPHAC---ENVVGSYICKCPEGYRRTSAPQDSE-NACEDINECEEQEDLCSGGV- 610
Q+ R C C + V + C+C G+ S + C+DINEC + G
Sbjct: 24 QDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFS 83
Query: 611 -CINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
C NT+GS+ C C G+EP + TC
Sbjct: 84 DCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTC 117
Score = 34.3 bits (75), Expect = 1.9
Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 7/73 (9%)
Query: 54 PGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCD------HGYEHDNTSHL 106
PG P + +DEC C T C +T + C C HG ++ +
Sbjct: 199 PGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTV 258
Query: 107 CRDVDECSWGRPP 119
C D+ +W PP
Sbjct: 259 CEDMTFSTWTPPP 271
>AB065931-1|BAC06146.1| 837|Homo sapiens seven transmembrane helix
receptor protein.
Length = 837
Score = 153 bits (372), Expect = 2e-36
Identities = 88/218 (40%), Positives = 111/218 (50%), Gaps = 33/218 (15%)
Query: 120 CRGMAQCVNLPGAFECRCPPGYR-----LTPSLDECEDVDECGDQRICDHG---DCRNTI 171
C + CVN A CRC PG+ +T ++ C+D++EC G DC NT
Sbjct: 34 CPQDSSCVN---ATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTE 90
Query: 172 GSYRCECKPGY-------TLR---ENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDD 220
GSY C C PGY T + EN C+DVDEC + +C++ GTC N G+Y C C
Sbjct: 91 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 150
Query: 221 GFKAGPNND--CVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTL---TADGRN--- 271
GFK P + C DVNEC G C + C N VGS++C C PG+ + +G N
Sbjct: 151 GFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTV 210
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
C DVDEC H C D + C NT G Y C C GWK
Sbjct: 211 CEDVDECSSGQHQC--DSSTVCFNTVGSYSCRCRPGWK 246
Score = 122 bits (294), Expect = 5e-27
Identities = 70/196 (35%), Positives = 95/196 (48%), Gaps = 25/196 (12%)
Query: 426 DLDECRVRPDVCVG--GRCVNTDGSFRCECPDGYVLAPDGLS--------CVDADECALD 475
D++EC V G C NT+GS+ C C GY + C D DEC +
Sbjct: 68 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 127
Query: 476 PRICGN-GTCSNTRGGYECQCSPGFTQGPD--QTCVDVDECAEGRASC--TFRCHNTAGS 530
PR+C + GTC NT G Y CQC PGF P+ + C DV+EC G+ C + C N GS
Sbjct: 128 PRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGS 187
Query: 531 FRCTCPYGYAV------AADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYR- 581
++C C G+ + C D+DEC C + C N VGSY C+C G++
Sbjct: 188 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 247
Query: 582 RTSAPQD-SENACEDI 596
R P + + CED+
Sbjct: 248 RHGIPNNQKDTVCEDM 263
Score = 120 bits (289), Expect = 2e-26
Identities = 73/211 (34%), Positives = 99/211 (46%), Gaps = 27/211 (12%)
Query: 442 CVNTDGSFRCECPDGY-----VLAPDGLSCVDADECALDPRI-CGN-GTCSNTRGGYECQ 494
CVN C C G+ ++ +C D +ECA ++ CG C NT G Y+C
Sbjct: 40 CVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCV 96
Query: 495 CSPG---------FTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFRCTCPYGYAVAA 543
CSPG F + TC DVDEC + C C NT GS+ C C G+ +
Sbjct: 97 CSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKP 156
Query: 544 -DGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSEN--ACEDINE 598
D C D++EC C + C N VGSY C+C G++ + N CED++E
Sbjct: 157 EDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDE 216
Query: 599 CEEQEDLC-SGGVCINTDGSFLCDCDAGFEP 628
C + C S VC NT GS+ C C G++P
Sbjct: 217 CSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 247
Score = 118 bits (283), Expect = 1e-25
Identities = 74/233 (31%), Positives = 104/233 (44%), Gaps = 33/233 (14%)
Query: 146 SLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY-------TLRENVCRDVDECSRP 198
+L E D G R C + + + C C PG+ T C D++EC+
Sbjct: 18 TLPGAETQDSRGCARWCPQDS--SCVNATACRCNPGFSSFSEIITTPMETCDDINECATL 75
Query: 199 RPV-C-RNGTCENLPGAYLCHCDDG---------FKAGPNNDCVDVNECREGGMVCRN-G 246
V C + C N G+Y C C G FK N C DV+EC++ +C++ G
Sbjct: 76 SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYG 135
Query: 247 RCRNTVGSFRCECAPGYTL-TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C NT+GS+ C+C PG+ L D + C DV+EC +PC + C N G Y+C C
Sbjct: 136 TCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPC--HSSTHCLNNVGSYQCRCR 193
Query: 306 AGWKLV--------GRRCVDRDECKELPYVC-AGGECRNFNGGYVCECPAGWR 349
GW+ + C D DEC + C + C N G Y C C GW+
Sbjct: 194 PGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 246
Score = 116 bits (278), Expect = 5e-25
Identities = 67/198 (33%), Positives = 96/198 (48%), Gaps = 19/198 (9%)
Query: 1 MEWNEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
ME ++ CA V K+ C + ++ C SP + + G K + N
Sbjct: 63 METCDDINECATLSKVSCGKFSDCWNTEGSYDCVC-------SPGYEPVSGAKT--FKNE 113
Query: 61 VTNETKPIDECDIMPQLCKP-GTCHDTPTGFQCGCDHGYE-HDNTSHLCRDVDECSWGRP 118
N + +DEC P+LCK GTC +T + C C G++ LC DV+EC+ G+
Sbjct: 114 SENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQN 173
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDE------CEDVDECGD-QRICDHGD-CRNT 170
PC C+N G+++CRC PG++ P CEDVDEC Q CD C NT
Sbjct: 174 PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNT 233
Query: 171 IGSYRCECKPGYTLRENV 188
+GSY C C+PG+ R +
Sbjct: 234 VGSYSCRCRPGWKPRHGI 251
Score = 104 bits (250), Expect = 1e-21
Identities = 54/130 (41%), Positives = 71/130 (54%), Gaps = 12/130 (9%)
Query: 422 NLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAP-DGLSCVDADECALDPRIC 479
N QD+DEC+ P +C G CVNT GS+ C+C G+ L P D C D +EC C
Sbjct: 116 NTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPC 175
Query: 480 GNGT-CSNTRGGYECQCSPGF------TQGPDQT-CVDVDECAEGRASC--TFRCHNTAG 529
+ T C N G Y+C+C PG+ GP+ T C DVDEC+ G+ C + C NT G
Sbjct: 176 HSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVG 235
Query: 530 SFRCTCPYGY 539
S+ C C G+
Sbjct: 236 SYSCRCRPGW 245
Score = 86.2 bits (204), Expect = 4e-16
Identities = 50/129 (38%), Positives = 61/129 (47%), Gaps = 21/129 (16%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYRPAGE---VCADVDECAVRPPPCDQLC 795
DVDEC P LC G + C C PG++ E +C DV+EC PC
Sbjct: 120 DVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSST 179
Query: 796 H--NTDGSYDCLCRTGYEL---DEDGAN---CRDVDECERDTHTCQQ--ICSNTEGSYEC 845
H N GSY C CR G++ +G N C DVDEC H C +C NT GSY C
Sbjct: 180 HCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSC 239
Query: 846 SCEDGYEKR 854
C G++ R
Sbjct: 240 RCRPGWKPR 248
Score = 78.6 bits (185), Expect = 9e-14
Identities = 42/107 (39%), Positives = 50/107 (46%), Gaps = 15/107 (14%)
Query: 761 GRFRCVCGPGYRPAG----------EVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRT 808
G + CVC PGY P C DVDEC P C C NT GSY C C
Sbjct: 91 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 150
Query: 809 GYEL-DEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE 852
G++L ED C DV+EC + C C N GSY+C C G++
Sbjct: 151 GFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 197
Score = 74.1 bits (174), Expect = 2e-12
Identities = 40/108 (37%), Positives = 56/108 (51%), Gaps = 20/108 (18%)
Query: 765 CVCGPGYRPAGEV-------CADVDECA-VRPPPCDQL--CHNTDGSYDCLCRTGYE--- 811
C C PG+ E+ C D++ECA + C + C NT+GSYDC+C GYE
Sbjct: 46 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 105
Query: 812 -----LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE 852
+E C+DVDEC+++ C+ C NT GSY C C G++
Sbjct: 106 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 153
Score = 73.7 bits (173), Expect = 2e-12
Identities = 41/99 (41%), Positives = 53/99 (53%), Gaps = 9/99 (9%)
Query: 548 CRDIDECVQEPRV-CPHA--CENVVGSYICKCPEGYRRTSAPQ----DSENACEDINECE 600
C DI+EC +V C C N GSY C C GY S + +SEN C+D++EC+
Sbjct: 66 CDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQ 125
Query: 601 EQEDLC-SGGVCINTDGSFLCDCDAGFE-PSEDGTDCID 637
+ LC S G C+NT GS+ C C GF+ ED C D
Sbjct: 126 QNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTD 164
Score = 72.5 bits (170), Expect = 6e-12
Identities = 70/264 (26%), Positives = 96/264 (36%), Gaps = 46/264 (17%)
Query: 259 CAPGYT------LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
C+P Y LT G +D C C +D SC N C C G+
Sbjct: 5 CSPSYLGAFCVWLTLPGAETQDSRGCARW---CPQDS--SCVNATA---CRCNPGFSSFS 56
Query: 313 R-------RCVDRDECKELPYVCAG--GECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
C D +EC L V G +C N G Y C C G+ A +E +
Sbjct: 57 EIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESEN 116
Query: 364 LCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNL 423
C D C + P C S G C + + + + P L
Sbjct: 117 TCQD---VDECQQ-------NPRLCKSYGT-----CVNTLGSYTCQCLPGFKLKPEDPKL 161
Query: 424 TQDLDECRVRPDVCVGG-RCVNTDGSFRCECPDGY------VLAPDGLSCVDADECALDP 476
D++EC + C C+N GS++C C G+ P+ C D DEC+
Sbjct: 162 CTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQ 221
Query: 477 RICGNGT-CSNTRGGYECQCSPGF 499
C + T C NT G Y C+C PG+
Sbjct: 222 HQCDSSTVCFNTVGSYSCRCRPGW 245
Score = 47.2 bits (107), Expect = 2e-04
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 6/94 (6%)
Query: 556 QEPRVCPHAC---ENVVGSYICKCPEGYRRTSAPQDSE-NACEDINECEEQEDLCSGGV- 610
Q+ R C C + V + C+C G+ S + C+DINEC + G
Sbjct: 25 QDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFS 84
Query: 611 -CINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
C NT+GS+ C C G+EP + TC
Sbjct: 85 DCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTC 118
Score = 34.3 bits (75), Expect = 1.9
Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 7/73 (9%)
Query: 54 PGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCD------HGYEHDNTSHL 106
PG P + +DEC C T C +T + C C HG ++ +
Sbjct: 200 PGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTV 259
Query: 107 CRDVDECSWGRPP 119
C D+ +W PP
Sbjct: 260 CEDMTFSTWTPPP 272
>AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein.
Length = 502
Score = 153 bits (372), Expect = 2e-36
Identities = 144/452 (31%), Positives = 194/452 (42%), Gaps = 81/452 (17%)
Query: 64 ETKPIDECDIMPQLC-KPGTCHDTPTGF-QCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
+ K D C P C K G CH +G QC C G+ T C+ D CS PC
Sbjct: 114 QAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGW----TGEQCQLRDFCSAN--PCV 165
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDEC-GDQRICDHG-DCRNTIGSYRCEC 178
C+ +C CPPG+ CE DV+EC D C G C NT+GS++C C
Sbjct: 166 NGGVCLATYPQIQCHCPPGFEG----HACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 221
Query: 179 KPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGA----YLCHCDDGFKAGPNNDCVDVN 234
G R C PR GTC+ +P +LC C GF GP C +VN
Sbjct: 222 PVGQEGPRCELR-AGPCP-PRGCSNGGTCQLMPEKDSTFHLCLCPPGF-IGPG--C-EVN 275
Query: 235 ECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPS 292
C+NG C++ + ++ C C +T G +C DVDEC+ P R+G +
Sbjct: 276 PDNCVSHQCQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECEAQGPPHCRNGG-T 330
Query: 293 CTNTNGGYECSCGAGWKLVGRRCVDR-DECKELPYVCA-GGECRNFNGGYVCECPAGWRF 350
C N+ G + C C +GW G C + D+C + CA G C + G + C CP G
Sbjct: 331 CQNSAGSFHCVCVSGWG--GTSCEENLDDC--IAATCAPGSTCIDRVGSFSCLCPPG--- 383
Query: 351 DKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEF 410
+T +C +++C + CH + CS P +
Sbjct: 384 -RTGLLC--HLEDMCLSQ----PCHG---------DAQCSTN------------PLTGST 415
Query: 411 MRICQGGMGRPNLTQDLDECRVR---PDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC 466
+ +CQ G P QDLDEC + P C GG C+NT GSF C CP GY G C
Sbjct: 416 LCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT----GSRC 471
Query: 467 -VDADECALDPRICGNGTCSNTRGGYECQCSP 497
D +EC P G+ TC + + C C P
Sbjct: 472 EADHNECLSQPCHPGS-TCLDLLATFHCLCPP 502
Score = 148 bits (358), Expect = 1e-34
Identities = 146/507 (28%), Positives = 209/507 (41%), Gaps = 86/507 (16%)
Query: 119 PCRGMAQCVNLP-GAFECRCPPGYRLTPSLDECEDVDECGDQRICDHG-DCRNTIG---- 172
PC C++L G C+C PG+ + C+ D C + ++C +G C+ +
Sbjct: 33 PCANGGTCLSLSLGQGTCQCAPGFLG----ETCQFPDPCQNAQLCQNGGSCQALLPAPLG 88
Query: 173 ----------SYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCE-NLPGAYLCHCDDG 221
S+ C C PG+T + D C P + G C G C C G
Sbjct: 89 LPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCP-PSFCSKRGRCHIQASGRPQCSCMPG 147
Query: 222 FKAGPNN--DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNC-RDVDEC 278
+ D N C GG+ C T +C C PG+ +G C RDV+EC
Sbjct: 148 WTGEQCQLRDFCSANPCVNGGV------CLATYPQIQCHCPPGF----EGHACERDVNEC 197
Query: 279 DELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDR-DECKELPYVCA-GGECRNF 336
+ P PC + SC NT G ++C C G + G RC R C P C+ GG C+
Sbjct: 198 FQDPGPCPK--GTSCHNTLGSFQCLCPVGQE--GPRCELRAGPCP--PRGCSNGGTCQLM 251
Query: 337 ----NGGYVCECPAGW---RFDKTAAVCVDERKE---LCYDEWEAGRCHRARPLQLARPE 386
+ ++C CP G+ + CV + + C D + C P +
Sbjct: 252 PEKDSTFHLCLCPPGFIGPGCEVNPDNCVSHQCQNGGTCQDGLDTYTC--LCPETWTGWD 309
Query: 387 C------CCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGG 440
C C ++G R C + F +C G G + ++LD+C + G
Sbjct: 310 CSEDVDECEAQGPPHCRNGGTCQN-SAGSFHCVCVSGWGGTSCEENLDDC-IAATCAPGS 367
Query: 441 RCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRIC-GNGTCSNT--RGGYECQCSP 497
C++ GSF C CP G GL C D C P C G+ CS G C C P
Sbjct: 368 TCIDRVGSFSCLCPPGRT----GLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTLCLCQP 421
Query: 498 GFTQGPDQTC-VDVDECA---EGRASCTF--RCHNTAGSFRCTCPYGYAVAADGVHCR-D 550
G++ GP TC D+DEC +G + C C NT GSF C CP GY G C D
Sbjct: 422 GYS-GP--TCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT----GSRCEAD 474
Query: 551 IDECVQEPRVCPHACENVVGSYICKCP 577
+EC+ +P C +++ ++ C CP
Sbjct: 475 HNECLSQPCHPGSTCLDLLATFHCLCP 501
Score = 145 bits (352), Expect = 5e-34
Identities = 154/527 (29%), Positives = 211/527 (40%), Gaps = 105/527 (19%)
Query: 165 GDCRN-TIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCE-------NLPGA-- 213
G C + ++G C+C PG+ L E C+ D C + +C+NG +C+ LP +
Sbjct: 38 GTCLSLSLGQGTCQCAPGF-LGET-CQFPDPCQNAQ-LCQNGGSCQALLPAPLGLPSSPS 94
Query: 214 -----YLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCR-NTVGSFRCECAPGYTLTA 267
+LC C GF G + C + GRC G +C C PG+T
Sbjct: 95 PLTPSFLCTCLPGF-TGERCQAKLEDPCPPS-FCSKRGRCHIQASGRPQCSCMPGWT--- 149
Query: 268 DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV-DRDECKELPY 326
G C+ D C +PC G C T +C C G++ G C D +EC + P
Sbjct: 150 -GEQCQLRDFCSA--NPCVNGG--VCLATYPQIQCHCPPGFE--GHACERDVNECFQDPG 202
Query: 327 VCAGG-ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARP 385
C G C N G + C CP G + C E AG C P
Sbjct: 203 PCPKGTSCHNTLGSFQCLCPVG------------QEGPRC--ELRAGPC----------P 238
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN- 444
CS G C+ P DS + +C G P C V PD CV +C N
Sbjct: 239 PRGCSNGGT----CQLMPEKDSTFHLCLCPPGFIGPG-------CEVNPDNCVSHQCQNG 287
Query: 445 ---TDG--SFRCECPDGYVLAPDGLSCV-DADEC-ALDPRICGNG-TCSNTRGGYECQCS 496
DG ++ C CP+ + G C D DEC A P C NG TC N+ G + C C
Sbjct: 288 GTCQDGLDTYTCLCPETWT----GWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCV 343
Query: 497 PGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQ 556
G+ G ++D+C + C + GSF C CP G G+ C D C+
Sbjct: 344 SGW--GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMCLS 397
Query: 557 EPRVCPHACEN--VVGSYICKCPEGYRRTSAPQDSEN---ACEDINECEEQEDLCSGGVC 611
+P C + GS +C C GY + QD + A + + CE GG C
Sbjct: 398 QPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH------GGSC 451
Query: 612 INTDGSFLCDCDAGFEPSE---DGTDCIDRRT---GTCYRSLVSGRC 652
+NT GSF C C G+ S D +C+ + TC L + C
Sbjct: 452 LNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 498
Score = 119 bits (287), Expect = 4e-26
Identities = 143/510 (28%), Positives = 193/510 (37%), Gaps = 79/510 (15%)
Query: 71 CDIMPQLC-KPGTCHDTPTGF-QCGCDHGYEHDN--------TSHLCRDVDECSWGRPPC 120
C P+ C GTC G C C G+ + + LC++ C P
Sbjct: 27 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAP 86
Query: 121 RGMAQCVN-LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCR-NTIGSYRCEC 178
G+ + L +F C C PG+ T + + D C G C G +C C
Sbjct: 87 LGLPSSPSPLTPSFLCTCLPGF--TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSC 144
Query: 179 KPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCV-DVNECR 237
PG+T + C+ D CS P G C CHC GF+ + C DVNEC
Sbjct: 145 MPGWTGEQ--CQLRDFCSA-NPCVNGGVCLATYPQIQCHCPPGFEG---HACERDVNECF 198
Query: 238 EGGMVCRNGR-CRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTN 295
+ C G C NT+GSF+C C G +G C C P C G
Sbjct: 199 QDPGPCPKGTSCHNTLGSFQCLCPVGQ----EGPRCELRAGPCP--PRGCSNGGTCQLMP 252
Query: 296 TNGG--YECSCGAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYVCECP---AGW 348
+ C C G+ +G C V+ D C + + C GG C++ Y C CP GW
Sbjct: 253 EKDSTFHLCLCPPGF--IGPGCEVNPDNC--VSHQCQNGGTCQDGLDTYTCLCPETWTGW 308
Query: 349 RFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWG-RYCER----CP 403
+ C + C + G C + C C G WG CE C
Sbjct: 309 DCSEDVDECEAQGPPHCRN---GGTCQNSA----GSFHCVCVSG--WGGTSCEENLDDCI 359
Query: 404 A----PDSAEFMRI----CQGGMGRPNLTQDLDE-CRVRPDVCVGGRCVNTD---GSFRC 451
A P S R+ C GR L L++ C +P C G +T+ GS C
Sbjct: 360 AATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTLC 417
Query: 452 ECPDGYVLAPDGLSC-VDADECAL---DPRICGNG-TCSNTRGGYECQCSPGFTQGPDQT 506
C GY G +C D DEC + P C +G +C NT G + C C PG+T +
Sbjct: 418 LCQPGY----SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCE- 472
Query: 507 CVDVDECAEGRASCTFRCHNTAGSFRCTCP 536
D +EC C + +F C CP
Sbjct: 473 -ADHNECLSQPCHPGSTCLDLLATFHCLCP 501
Score = 101 bits (242), Expect = 1e-20
Identities = 103/352 (29%), Positives = 142/352 (40%), Gaps = 52/352 (14%)
Query: 21 YLCCCSVGHAWGAPCEA-----CPP----RGSPAHTALCGEKPGEYINPVTNETKPI-DE 70
+LC C G G C+A CPP + H G + T E + D
Sbjct: 100 FLCTCLPGFT-GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDF 158
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNL 129
C P + G C T QC C G+E H C RDV+EC PC C N
Sbjct: 159 CSANPCV-NGGVCLATYPQIQCHCPPGFE----GHACERDVNECFQDPGPCPKGTSCHNT 213
Query: 130 PGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCR----NTIGSYRCECKPGYTL 184
G+F+C CP G P CE C + + G C+ + C C PG+ +
Sbjct: 214 LGSFQCLCPVGQE-GP---RCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGF-I 268
Query: 185 RENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCV-DVNECR-EGGM 241
+ D C + C+NG TC++ Y C C + + DC DV+EC +G
Sbjct: 269 GPGCEVNPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGW---DCSEDVDECEAQGPP 323
Query: 242 VCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGG 299
CRNG C+N+ GSF C C G+ G +C + +D+C + C +C + G
Sbjct: 324 HCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDC--IAATCA--PGSTCIDRVGS 375
Query: 300 YECSCGAGWKLVGRRCVDRDECKELPYVCAG-GECRN--FNGGYVCECPAGW 348
+ C C G G C D C P C G +C G +C C G+
Sbjct: 376 FSCLCPPG--RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTLCLCQPGY 423
Score = 67.3 bits (157), Expect = 2e-10
Identities = 106/404 (26%), Positives = 136/404 (33%), Gaps = 72/404 (17%)
Query: 472 CALDPRICGNG-TC-SNTRGGYECQCSPGFT----QGPDQTCVDVDECAEGRASCTFRCH 525
C P C NG TC S + G CQC+PGF Q PD C + C G SC
Sbjct: 27 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDP-CQNAQLCQNG-GSCQALLP 84
Query: 526 NTAG----------SFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA--CE-NVVGSY 572
G SF CTC G+ G C+ E P C C G
Sbjct: 85 APLGLPSSPSPLTPSFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRP 140
Query: 573 ICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDG 632
C C G+ T + C N C +GGVC+ T C C GFE G
Sbjct: 141 QCSCMPGW--TGEQCQLRDFCS-ANPC------VNGGVCLATYPQIQCHCPPGFE----G 187
Query: 633 TDCIDRRTGTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXXXGHVTKAQCCCTLGAA 692
C +R C++ G C P+ QC C +G
Sbjct: 188 HAC-ERDVNECFQD--PGPC-PKGTSCHNTLGSF-----------------QCLCPVGQE 226
Query: 693 WGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVDECA 752
G CEL P P L P +C
Sbjct: 227 -GPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPDNCVSHQCQ 285
Query: 753 AIPGLCAPG--RFRCVCGPGYRPAGEVCADVDECAVRPPP-CDQ--LCHNTDGSYDCLCR 807
G C G + C+C P + DVDEC + PP C C N+ GS+ C+C
Sbjct: 286 N-GGTCQDGLDTYTCLC-PETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCV 343
Query: 808 TGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDG 850
+G+ G +C + +D+C T C + GS+ C C G
Sbjct: 344 SGW----GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG 383
Score = 58.4 bits (135), Expect = 1e-07
Identities = 37/97 (38%), Positives = 47/97 (48%), Gaps = 9/97 (9%)
Query: 759 APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
A GR +C C PG+ GE C D C+ P +C T C C G+E G
Sbjct: 136 ASGRPQCSCMPGW--TGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFE----GHA 189
Query: 819 C-RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE 852
C RDV+EC +D C + C NT GS++C C G E
Sbjct: 190 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE 226
Score = 56.4 bits (130), Expect = 4e-07
Identities = 42/121 (34%), Positives = 55/121 (45%), Gaps = 24/121 (19%)
Query: 747 DVDECAAIPGLCAPGR--------FRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNT 798
++D+C A CAPG F C+C PG G +C D C +P D C
Sbjct: 354 NLDDCIA--ATCAPGSTCIDRVGSFSCLCPPGR--TGLLCHLEDMCLSQPCHGDAQCSTN 409
Query: 799 D--GSYDCLCRTGYELDEDGANC-RDVDEC---ERDTHTCQQ--ICSNTEGSYECSCEDG 850
GS CLC+ GY G C +D+DEC ++ C+ C NT GS+ C C G
Sbjct: 410 PLTGSTLCLCQPGYS----GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPG 465
Query: 851 Y 851
Y
Sbjct: 466 Y 466
Score = 53.6 bits (123), Expect = 3e-06
Identities = 33/94 (35%), Positives = 45/94 (47%), Gaps = 13/94 (13%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDECAVR---PPPCDQ--LCHNTDGSYDCLCRTGYELDE 814
G C+C PGY +G C D+DEC + P PC+ C NT GS++CLC GY
Sbjct: 413 GSTLCLCQPGY--SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY---- 466
Query: 815 DGANCR-DVDECERDTHTCQQICSNTEGSYECSC 847
G+ C D +EC C + ++ C C
Sbjct: 467 TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLC 500
Score = 51.2 bits (117), Expect = 2e-05
Identities = 38/117 (32%), Positives = 52/117 (44%), Gaps = 20/117 (17%)
Query: 749 DECAAIP----GLCAPG--RFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTD 799
D C+A P G+C + +C C PG+ G C DV+EC P PC + CHNT
Sbjct: 157 DFCSANPCVNGGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSCHNTL 214
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECE----RDTHTCQQICSNTEGSYECSCEDGY 851
GS+ CLC G ++G C C + TCQ + + C C G+
Sbjct: 215 GSFQCLCPVG----QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGF 267
Score = 43.6 bits (98), Expect = 0.003
Identities = 30/92 (32%), Positives = 42/92 (45%), Gaps = 11/92 (11%)
Query: 765 CVCGPGY-RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDV 822
C+C PG+ P EV + D C C + +Y CLC + G +C DV
Sbjct: 261 CLCPPGFIGPGCEV--NPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT----GWDCSEDV 314
Query: 823 DECE-RDTHTCQQ--ICSNTEGSYECSCEDGY 851
DECE + C+ C N+ GS+ C C G+
Sbjct: 315 DECEAQGPPHCRNGGTCQNSAGSFHCVCVSGW 346
>BC127263-1|AAI27264.1| 363|Homo sapiens SCUBE1 protein protein.
Length = 363
Score = 152 bits (369), Expect = 4e-36
Identities = 112/350 (32%), Positives = 148/350 (42%), Gaps = 39/350 (11%)
Query: 274 DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAG--G 331
DVDEC E C D C NT Y+C C G+K G++C D DEC E Y G
Sbjct: 33 DVDECSEGTDDCHIDA--ICQNTPKSYKCLCKPGYKGEGKQCEDIDEC-ENDYYNGGCVH 89
Query: 332 ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSE 391
EC N G Y C C G+ C+D + C D G C + + EC C
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDGHNCLDVDE--CQDN--NGGCQQICVNAMGSYECQCHS 145
Query: 392 GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRC 451
G C S E M G ++ CR P G C
Sbjct: 146 GFFLSDNQHTC-IHRSNEGMNCMNKDHGCAHI------CRETPK-----------GGVAC 187
Query: 452 ECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QTCVDV 510
+C G+ LA + C C C + +C +T G C C + D +TC++
Sbjct: 188 DCRPGFDLAQNQKDCTLT--CNYGNGGCQH-SCEDTDTGPMCGCHQKYALHSDGRTCIET 244
Query: 511 DECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG 570
CA C C +TA RC+CP G+ + DG C+DI+EC+ C H C N VG
Sbjct: 245 --CAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVG 302
Query: 571 SYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC 620
S+ C C +GY+ + E C+DI+EC E C +CIN+ GSF C
Sbjct: 303 SFECGCRKGYKLLT----DERTCQDIDEC-SFERTCD-HICINSPGSFQC 346
Score = 138 bits (333), Expect = 1e-31
Identities = 92/302 (30%), Positives = 125/302 (41%), Gaps = 22/302 (7%)
Query: 68 IDECDIMPQLCK-PGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
+DEC C C +TP ++C C GY+ + C D+DEC + +C
Sbjct: 34 VDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQ--CEDIDECENDYYNGGCVHEC 91
Query: 127 VNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRE 186
+N+PG + C C G+ L C DVDEC D C N +GSY C+C G+ L +
Sbjct: 92 INIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSD 151
Query: 187 N--VC----RDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREG 239
N C + C C + E G C C GF N DC C G
Sbjct: 152 NQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDC--TLTCNYG 209
Query: 240 GMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGG 299
C++ C +T C C Y L +DGR C ++ C C R +C +T G
Sbjct: 210 NGGCQHS-CEDTDTGPMCGCHQKYALHSDGRTC--IETCAVNNGGCDR----TCKDTATG 262
Query: 300 YECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVC 357
CSC G+ L G+ C D +EC C CRN G + C C G++ C
Sbjct: 263 VRCSCPVGFTLQPDGKTCKDINECLVNNGGC-DHFCRNTVGSFECGCRKGYKLLTDERTC 321
Query: 358 VD 359
D
Sbjct: 322 QD 323
Score = 127 bits (306), Expect = 2e-28
Identities = 99/320 (30%), Positives = 132/320 (41%), Gaps = 33/320 (10%)
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRI---CDHG 165
DVDECS G C A C N P +++C C PGY+ +CED+DEC + C H
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDECENDYYNGGCVH- 89
Query: 166 DCRNTIGSYRCECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK 223
+C N G+YRC C G+ L + C DVDEC C+ C N G+Y C C GF
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSGFF 148
Query: 224 AGPNNDCVDVNECREGGMVCRNGR------CRNT-VGSFRCECAPGYTLTADGRNCRDVD 276
N ++ E GM C N CR T G C+C PG+ L + ++C
Sbjct: 149 LSDNQHTC-IHRSNE-GMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDC--TL 204
Query: 277 ECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDECKELPYVCAGGECR 334
C+ C SC +T+ G C C + L GR C+ + C C C+
Sbjct: 205 TCNYGNGGC----QHSCEDTDTGPMCGCHQKYALHSDGRTCI--ETCAVNNGGC-DRTCK 257
Query: 335 NFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAA 394
+ G C CP G+ C D + L + G C + EC C +G
Sbjct: 258 DTATGVRCSCPVGFTLQPDGKTCKDINECLVNN----GGCDHFCRNTVGSFECGCRKGYK 313
Query: 395 WGRYCERCPAPDSAEFMRIC 414
C D F R C
Sbjct: 314 LLTDERTCQDIDECSFERTC 333
Score = 118 bits (285), Expect = 7e-26
Identities = 58/173 (33%), Positives = 85/173 (49%), Gaps = 6/173 (3%)
Query: 467 VDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEG--RASCTFR 523
VD DEC+ C + C NT Y+C C PG+ +G + C D+DEC C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGY-KGEGKQCEDIDECENDYYNGGCVHE 90
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRT 583
C N G++RCTC G+ +A DG +C D+DEC C C N +GSY C+C G+ +
Sbjct: 91 CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLS 150
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINT-DGSFLCDCDAGFEPSEDGTDC 635
+ + C ++ C+ +C T G CDC GF+ +++ DC
Sbjct: 151 DNQHTCIHRSNEGMNCMNKDHGCA-HICRETPKGGVACDCRPGFDLAQNQKDC 202
Score = 111 bits (266), Expect = 1e-23
Identities = 93/327 (28%), Positives = 126/327 (38%), Gaps = 40/327 (12%)
Query: 316 VDRDECKELPYVC-AGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC 374
VD DEC E C C+N Y C C G++ + +DE C +++ G C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDE----CENDYYNGGC 87
Query: 375 HRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRP 434
EC G Y RC D FM G + D+DEC+
Sbjct: 88 VH---------ECINIPG----NY--RCTCFDG--FMLAHDG-----HNCLDVDECQDNN 125
Query: 435 DVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV----DADECALDPRICGNGTCSNTRGG 490
C CVN GS+ C+C G+ L+ + +C+ + C C + +GG
Sbjct: 126 GGCQQ-ICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGG 184
Query: 491 YECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRD 550
C C PGF +Q + C G C C +T C C YA+ +DG C
Sbjct: 185 VACDCRPGFDLAQNQKDCTLT-CNYGNGGCQHSCEDTDTGPMCGCHQKYALHSDGRTC-- 241
Query: 551 IDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV 610
I+ C C C++ C CP G+ Q C+DINEC C
Sbjct: 242 IETCAVNNGGCDRTCKDTATGVRCSCPVGFTL----QPDGKTCKDINECLVNNGGCDH-F 296
Query: 611 CINTDGSFLCDCDAGFEPSEDGTDCID 637
C NT GSF C C G++ D C D
Sbjct: 297 CRNTVGSFECGCRKGYKLLTDERTCQD 323
Score = 110 bits (264), Expect = 2e-23
Identities = 72/231 (31%), Positives = 95/231 (41%), Gaps = 20/231 (8%)
Query: 416 GGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECAL 474
GG G P + D+DEC D C + C NT S++C C GY +G C D DEC
Sbjct: 24 GGSGLPG-SVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGY--KGEGKQCEDIDECEN 80
Query: 475 DPRICG-NGTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFR 532
D G C N G Y C C GF D C+DVDEC + C C N GS+
Sbjct: 81 DYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYE 140
Query: 533 CTCPYGYAVAADGVHC----RDIDECVQEPRVCPHAC-ENVVGSYICKCPEGYRRTSAPQ 587
C C G+ ++ + C + C+ + C H C E G C C G+ +
Sbjct: 141 CQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQK 200
Query: 588 DSENACEDIN-ECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
D C N C+ C +TD +C C + DG CI+
Sbjct: 201 DCTLTCNYGNGGCQHS--------CEDTDTGPMCGCHQKYALHSDGRTCIE 243
Score = 106 bits (254), Expect = 4e-22
Identities = 50/115 (43%), Positives = 63/115 (54%), Gaps = 10/115 (8%)
Query: 747 DVDECAA------IPGLC--APGRFRCVCGPGYRPAGEVCADVDECA--VRPPPCDQLCH 796
DVDEC+ I +C P ++C+C PGY+ G+ C D+DEC C C
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHECI 92
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
N G+Y C C G+ L DG NC DVDEC+ + CQQIC N GSYEC C G+
Sbjct: 93 NIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGF 147
Score = 105 bits (251), Expect = 9e-22
Identities = 71/239 (29%), Positives = 100/239 (41%), Gaps = 14/239 (5%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQ- 125
+DEC C+ C + ++C C G+ + H C +E G A
Sbjct: 118 VDECQDNNGGCQQ-ICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHI 176
Query: 126 CVNLP-GAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTL 184
C P G C C PG+ L + +C G+ C H C +T C C Y L
Sbjct: 177 CRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGG-CQHS-CEDTDTGPMCGCHQKYAL 234
Query: 185 RENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVC 243
+ ++ C+ C + TC++ C C GF P+ C D+NEC C
Sbjct: 235 HSDGRTCIETCAVNNGGC-DRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGC 293
Query: 244 RNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC 302
+ CRNTVGSF C C GY L D R C+D+DEC C + C N+ G ++C
Sbjct: 294 DHF-CRNTVGSFECGCRKGYKLLTDERTCQDIDEC-SFERTC----DHICINSPGSFQC 346
Score = 100 bits (239), Expect = 3e-20
Identities = 52/135 (38%), Positives = 71/135 (52%), Gaps = 11/135 (8%)
Query: 508 VDVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQE--PRVCPH 563
VDVDEC+EG C C NT S++C C GY +G C DIDEC + C H
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDECENDYYNGGCVH 89
Query: 564 ACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCD 623
C N+ G+Y C C +G+ D N C D++EC++ C +C+N GS+ C C
Sbjct: 90 ECINIPGNYRCTCFDGFMLA---HDGHN-CLDVDECQDNNGGCQQ-ICVNAMGSYECQCH 144
Query: 624 AGFEPSEDGTDCIDR 638
+GF S++ CI R
Sbjct: 145 SGFFLSDNQHTCIHR 159
Score = 91.9 bits (218), Expect = 9e-18
Identities = 38/84 (45%), Positives = 52/84 (61%), Gaps = 3/84 (3%)
Query: 764 RCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 821
RC C G+ +P G+ C D++EC V CD C NT GS++C CR GY+L D C+D
Sbjct: 264 RCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQD 323
Query: 822 VDECERDTHTCQQICSNTEGSYEC 845
+DEC + TC IC N+ GS++C
Sbjct: 324 IDECSFE-RTCDHICINSPGSFQC 346
Score = 75.8 bits (178), Expect = 6e-13
Identities = 36/100 (36%), Positives = 48/100 (48%), Gaps = 7/100 (7%)
Query: 760 PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG +RC C G+ A G C DVDEC C Q+C N GSY+C C +G+ L ++
Sbjct: 95 PGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQH 154
Query: 818 NC----RDVDECERDTHTCQQICSNT-EGSYECSCEDGYE 852
C + C H C IC T +G C C G++
Sbjct: 155 TCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFD 194
Score = 75.8 bits (178), Expect = 6e-13
Identities = 31/88 (35%), Positives = 43/88 (48%)
Query: 765 CVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDE 824
C C Y + ++ CAV CD+ C +T C C G+ L DG C+D++E
Sbjct: 226 CGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINE 285
Query: 825 CERDTHTCQQICSNTEGSYECSCEDGYE 852
C + C C NT GS+EC C GY+
Sbjct: 286 CLVNNGGCDHFCRNTVGSFECGCRKGYK 313
Score = 51.2 bits (117), Expect = 2e-05
Identities = 30/106 (28%), Positives = 39/106 (36%), Gaps = 2/106 (1%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
CA I G C C PG+ A C C C +TD C C Y
Sbjct: 173 CAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPMCGCHQKY 232
Query: 811 ELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
L DG C ++ C + C + C +T CSC G+ + D
Sbjct: 233 ALHSDGRTC--IETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPD 276
Score = 46.8 bits (106), Expect = 3e-04
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 9/69 (13%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNT 798
D++EC G C G F C C GY+ + C D+DEC+ CD +C N+
Sbjct: 282 DINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERT-CDHICINS 340
Query: 799 DGSYDCLCR 807
GS+ CL +
Sbjct: 341 PGSFQCLIK 349
Score = 44.8 bits (101), Expect = 0.001
Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Query: 821 DVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDAC 858
DVDEC T C IC NT SY+C C+ GY+ G C
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQC 72
>BC127005-1|AAI27006.1| 823|Homo sapiens egf-like module
containing, mucin-like, hormone receptor-like 2 protein.
Length = 823
Score = 152 bits (369), Expect = 4e-36
Identities = 88/218 (40%), Positives = 111/218 (50%), Gaps = 33/218 (15%)
Query: 120 CRGMAQCVNLPGAFECRCPPGYR-----LTPSLDECEDVDECGDQRICDHG---DCRNTI 171
C + CVN A CRC PG+ +T ++ C+D++EC G DC NT
Sbjct: 33 CPQDSSCVN---ATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTE 89
Query: 172 GSYRCECKPGY-------TLR---ENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDD 220
GSY C C PGY T + EN C+DVDEC + +C++ GTC N G+Y C C
Sbjct: 90 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 149
Query: 221 GFKAGPNND--CVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTL---TADGRN--- 271
GFK P + C DVNEC G C + C N VGS++C C PG+ + +G N
Sbjct: 150 GFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTV 209
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
C DVDEC H C D + C NT G Y C C GWK
Sbjct: 210 CEDVDECSSGQHQC--DSSTVCFNTVGSYSCRCRPGWK 245
Score = 121 bits (292), Expect = 1e-26
Identities = 70/196 (35%), Positives = 95/196 (48%), Gaps = 25/196 (12%)
Query: 426 DLDECRVRPDVCVG--GRCVNTDGSFRCECPDGYVLAPDGLS--------CVDADECALD 475
D++EC V G C NT+GS+ C C GY + C D DEC +
Sbjct: 67 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 126
Query: 476 PRICGN-GTCSNTRGGYECQCSPGFTQGPD--QTCVDVDECAEGRASC--TFRCHNTAGS 530
PR+C + GTC NT G Y CQC PGF P+ + C DV+EC G+ C + C N GS
Sbjct: 127 PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGS 186
Query: 531 FRCTCPYGYAV------AADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYR- 581
++C C G+ + C D+DEC C + C N VGSY C+C G++
Sbjct: 187 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 246
Query: 582 RTSAPQD-SENACEDI 596
R P + + CED+
Sbjct: 247 RHGIPNNQKDTVCEDM 262
Score = 121 bits (291), Expect = 1e-26
Identities = 73/211 (34%), Positives = 99/211 (46%), Gaps = 27/211 (12%)
Query: 442 CVNTDGSFRCECPDGY-----VLAPDGLSCVDADECALDPRI-CGN-GTCSNTRGGYECQ 494
CVN C C G+ ++ +C D +ECA ++ CG C NT G Y+C
Sbjct: 39 CVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCV 95
Query: 495 CSPG---------FTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFRCTCPYGYA-VA 542
CSPG F + TC DVDEC + C C NT GS+ C C G+ +
Sbjct: 96 CSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIP 155
Query: 543 ADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSEN--ACEDINE 598
D C D++EC C + C N VGSY C+C G++ + N CED++E
Sbjct: 156 EDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDE 215
Query: 599 CEEQEDLC-SGGVCINTDGSFLCDCDAGFEP 628
C + C S VC NT GS+ C C G++P
Sbjct: 216 CSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 246
Score = 117 bits (281), Expect = 2e-25
Identities = 73/233 (31%), Positives = 104/233 (44%), Gaps = 33/233 (14%)
Query: 146 SLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY-------TLRENVCRDVDECSRP 198
+L E D G R C + + + C C PG+ T C D++EC+
Sbjct: 17 TLPGAETQDSRGCARWCPQDS--SCVNATACRCNPGFSSFSEIITTPMETCDDINECATL 74
Query: 199 RPV-C-RNGTCENLPGAYLCHCDDG---------FKAGPNNDCVDVNECREGGMVCRN-G 246
V C + C N G+Y C C G FK N C DV+EC++ +C++ G
Sbjct: 75 SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYG 134
Query: 247 RCRNTVGSFRCECAPGYT-LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C NT+GS+ C+C PG+ + D + C DV+EC +PC + C N G Y+C C
Sbjct: 135 TCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPC--HSSTHCLNNVGSYQCRCR 192
Query: 306 AGWKLV--------GRRCVDRDECKELPYVC-AGGECRNFNGGYVCECPAGWR 349
GW+ + C D DEC + C + C N G Y C C GW+
Sbjct: 193 PGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245
Score = 114 bits (275), Expect = 1e-24
Identities = 66/198 (33%), Positives = 96/198 (48%), Gaps = 19/198 (9%)
Query: 1 MEWNEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
ME ++ CA V K+ C + ++ C SP + + G K + N
Sbjct: 62 METCDDINECATLSKVSCGKFSDCWNTEGSYDCVC-------SPGYEPVSGAKT--FKNE 112
Query: 61 VTNETKPIDECDIMPQLCKP-GTCHDTPTGFQCGCDHGYEH-DNTSHLCRDVDECSWGRP 118
N + +DEC P+LCK GTC +T + C C G++ +C DV+EC+ G+
Sbjct: 113 SENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQN 172
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDE------CEDVDECGD-QRICDHGD-CRNT 170
PC C+N G+++CRC PG++ P CEDVDEC Q CD C NT
Sbjct: 173 PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNT 232
Query: 171 IGSYRCECKPGYTLRENV 188
+GSY C C+PG+ R +
Sbjct: 233 VGSYSCRCRPGWKPRHGI 250
Score = 103 bits (246), Expect = 4e-21
Identities = 53/130 (40%), Positives = 70/130 (53%), Gaps = 12/130 (9%)
Query: 422 NLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAP-DGLSCVDADECALDPRIC 479
N QD+DEC+ P +C G CVNT GS+ C+C G+ P D C D +EC C
Sbjct: 115 NTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPC 174
Query: 480 GNGT-CSNTRGGYECQCSPGF------TQGPDQT-CVDVDECAEGRASC--TFRCHNTAG 529
+ T C N G Y+C+C PG+ GP+ T C DVDEC+ G+ C + C NT G
Sbjct: 175 HSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVG 234
Query: 530 SFRCTCPYGY 539
S+ C C G+
Sbjct: 235 SYSCRCRPGW 244
Score = 87.0 bits (206), Expect = 3e-16
Identities = 51/129 (39%), Positives = 61/129 (47%), Gaps = 21/129 (16%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYRPAGE---VCADVDECAVRPPPCDQLC 795
DVDEC P LC G + C C PG++ E VC DV+EC PC
Sbjct: 119 DVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSST 178
Query: 796 H--NTDGSYDCLCRTGYEL---DEDGAN---CRDVDECERDTHTCQQ--ICSNTEGSYEC 845
H N GSY C CR G++ +G N C DVDEC H C +C NT GSY C
Sbjct: 179 HCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSC 238
Query: 846 SCEDGYEKR 854
C G++ R
Sbjct: 239 RCRPGWKPR 247
Score = 77.8 bits (183), Expect = 2e-13
Identities = 68/231 (29%), Positives = 96/231 (41%), Gaps = 51/231 (22%)
Query: 252 VGSFRCECAPGYT-----LTADGRNCRDVDECDELPH-PCGRDGNPSCTNTNGGYECSCG 305
V + C C PG++ +T C D++EC L CG+ + C NT G Y+C C
Sbjct: 40 VNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSD--CWNTEGSYDCVCS 97
Query: 306 AGWKLVG----------RRCVDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRF-DKT 353
G++ V C D DEC++ P +C G C N G Y C+C G++F +
Sbjct: 98 PGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPED 157
Query: 354 AAVCVDERKELCYDEWEAGR--CHRARPL--QLARPECCCSEGAAWGRYCERCPAPDSAE 409
VC D +E +G+ CH + + +C C G W P P
Sbjct: 158 PKVCTD------VNECTSGQNPCHSSTHCLNNVGSYQCRCRPG--WQ------PIP---- 199
Query: 410 FMRICQGGMGRPNLT--QDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGY 457
G PN T +D+DEC C C NT GS+ C C G+
Sbjct: 200 ------GSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244
Score = 77.8 bits (183), Expect = 2e-13
Identities = 41/107 (38%), Positives = 50/107 (46%), Gaps = 15/107 (14%)
Query: 761 GRFRCVCGPGYRPAG----------EVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRT 808
G + CVC PGY P C DVDEC P C C NT GSY C C
Sbjct: 90 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 149
Query: 809 GYE-LDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE 852
G++ + ED C DV+EC + C C N GSY+C C G++
Sbjct: 150 GFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 196
Score = 74.1 bits (174), Expect = 2e-12
Identities = 40/108 (37%), Positives = 56/108 (51%), Gaps = 20/108 (18%)
Query: 765 CVCGPGYRPAGEV-------CADVDECA-VRPPPCDQL--CHNTDGSYDCLCRTGYE--- 811
C C PG+ E+ C D++ECA + C + C NT+GSYDC+C GYE
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 812 -----LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE 852
+E C+DVDEC+++ C+ C NT GSY C C G++
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 152
Score = 73.3 bits (172), Expect = 3e-12
Identities = 41/99 (41%), Positives = 53/99 (53%), Gaps = 9/99 (9%)
Query: 548 CRDIDECVQEPRV-CPHA--CENVVGSYICKCPEGYRRTSAPQ----DSENACEDINECE 600
C DI+EC +V C C N GSY C C GY S + +SEN C+D++EC+
Sbjct: 65 CDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQ 124
Query: 601 EQEDLC-SGGVCINTDGSFLCDCDAGFE-PSEDGTDCID 637
+ LC S G C+NT GS+ C C GF+ ED C D
Sbjct: 125 QNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTD 163
Score = 71.3 bits (167), Expect = 1e-11
Identities = 71/256 (27%), Positives = 95/256 (37%), Gaps = 48/256 (18%)
Query: 265 LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR-------RCVD 317
LT G +D C C +D SC N C C G+ C D
Sbjct: 16 LTLPGAETQDSRGCARW---CPQDS--SCVNATA---CRCNPGFSSFSEIITTPMETCDD 67
Query: 318 RDECKELPYVCAG--GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCH 375
+EC L V G +C N G Y C C G+ A +E + C D C
Sbjct: 68 INECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQD---VDECQ 124
Query: 376 RARPLQLARPECCCSEGA---AWGRY-CERCPAPDSAEFMRICQGGMGRPNLTQDLDECR 431
+ P C S G G Y C+ P F I + P + D++EC
Sbjct: 125 Q-------NPRLCKSYGTCVNTLGSYTCQCLPG-----FKFIPED----PKVCTDVNECT 168
Query: 432 VRPDVCVGG-RCVNTDGSFRCECPDGY------VLAPDGLSCVDADECALDPRICGNGT- 483
+ C C+N GS++C C G+ P+ C D DEC+ C + T
Sbjct: 169 SGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTV 228
Query: 484 CSNTRGGYECQCSPGF 499
C NT G Y C+C PG+
Sbjct: 229 CFNTVGSYSCRCRPGW 244
Score = 47.2 bits (107), Expect = 2e-04
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 6/94 (6%)
Query: 556 QEPRVCPHAC---ENVVGSYICKCPEGYRRTSAPQDSE-NACEDINECEEQEDLCSGGV- 610
Q+ R C C + V + C+C G+ S + C+DINEC + G
Sbjct: 24 QDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFS 83
Query: 611 -CINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
C NT+GS+ C C G+EP + TC
Sbjct: 84 DCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTC 117
Score = 34.3 bits (75), Expect = 1.9
Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 7/73 (9%)
Query: 54 PGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCD------HGYEHDNTSHL 106
PG P + +DEC C T C +T + C C HG ++ +
Sbjct: 199 PGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTV 258
Query: 107 CRDVDECSWGRPP 119
C D+ +W PP
Sbjct: 259 CEDMTFSTWTPPP 271
>BC127004-1|AAI27005.1| 823|Homo sapiens egf-like module
containing, mucin-like, hormone receptor-like 2 protein.
Length = 823
Score = 152 bits (369), Expect = 4e-36
Identities = 88/218 (40%), Positives = 111/218 (50%), Gaps = 33/218 (15%)
Query: 120 CRGMAQCVNLPGAFECRCPPGYR-----LTPSLDECEDVDECGDQRICDHG---DCRNTI 171
C + CVN A CRC PG+ +T ++ C+D++EC G DC NT
Sbjct: 33 CPQDSSCVN---ATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTE 89
Query: 172 GSYRCECKPGY-------TLR---ENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDD 220
GSY C C PGY T + EN C+DVDEC + +C++ GTC N G+Y C C
Sbjct: 90 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 149
Query: 221 GFKAGPNND--CVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTL---TADGRN--- 271
GFK P + C DVNEC G C + C N VGS++C C PG+ + +G N
Sbjct: 150 GFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTV 209
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
C DVDEC H C D + C NT G Y C C GWK
Sbjct: 210 CEDVDECSSGQHQC--DSSTVCFNTVGSYSCRCRPGWK 245
Score = 121 bits (292), Expect = 1e-26
Identities = 70/196 (35%), Positives = 95/196 (48%), Gaps = 25/196 (12%)
Query: 426 DLDECRVRPDVCVG--GRCVNTDGSFRCECPDGYVLAPDGLS--------CVDADECALD 475
D++EC V G C NT+GS+ C C GY + C D DEC +
Sbjct: 67 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 126
Query: 476 PRICGN-GTCSNTRGGYECQCSPGFTQGPD--QTCVDVDECAEGRASC--TFRCHNTAGS 530
PR+C + GTC NT G Y CQC PGF P+ + C DV+EC G+ C + C N GS
Sbjct: 127 PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGS 186
Query: 531 FRCTCPYGYAV------AADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYR- 581
++C C G+ + C D+DEC C + C N VGSY C+C G++
Sbjct: 187 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 246
Query: 582 RTSAPQD-SENACEDI 596
R P + + CED+
Sbjct: 247 RHGIPNNQKDTVCEDM 262
Score = 121 bits (291), Expect = 1e-26
Identities = 73/211 (34%), Positives = 99/211 (46%), Gaps = 27/211 (12%)
Query: 442 CVNTDGSFRCECPDGY-----VLAPDGLSCVDADECALDPRI-CGN-GTCSNTRGGYECQ 494
CVN C C G+ ++ +C D +ECA ++ CG C NT G Y+C
Sbjct: 39 CVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCV 95
Query: 495 CSPG---------FTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFRCTCPYGYA-VA 542
CSPG F + TC DVDEC + C C NT GS+ C C G+ +
Sbjct: 96 CSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIP 155
Query: 543 ADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSEN--ACEDINE 598
D C D++EC C + C N VGSY C+C G++ + N CED++E
Sbjct: 156 EDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDE 215
Query: 599 CEEQEDLC-SGGVCINTDGSFLCDCDAGFEP 628
C + C S VC NT GS+ C C G++P
Sbjct: 216 CSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 246
Score = 117 bits (281), Expect = 2e-25
Identities = 73/233 (31%), Positives = 104/233 (44%), Gaps = 33/233 (14%)
Query: 146 SLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY-------TLRENVCRDVDECSRP 198
+L E D G R C + + + C C PG+ T C D++EC+
Sbjct: 17 TLPGAETQDSRGCARWCPQDS--SCVNATACRCNPGFSSFSEIITTPMETCDDINECATL 74
Query: 199 RPV-C-RNGTCENLPGAYLCHCDDG---------FKAGPNNDCVDVNECREGGMVCRN-G 246
V C + C N G+Y C C G FK N C DV+EC++ +C++ G
Sbjct: 75 SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYG 134
Query: 247 RCRNTVGSFRCECAPGYT-LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C NT+GS+ C+C PG+ + D + C DV+EC +PC + C N G Y+C C
Sbjct: 135 TCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPC--HSSTHCLNNVGSYQCRCR 192
Query: 306 AGWKLV--------GRRCVDRDECKELPYVC-AGGECRNFNGGYVCECPAGWR 349
GW+ + C D DEC + C + C N G Y C C GW+
Sbjct: 193 PGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245
Score = 114 bits (275), Expect = 1e-24
Identities = 66/198 (33%), Positives = 96/198 (48%), Gaps = 19/198 (9%)
Query: 1 MEWNEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
ME ++ CA V K+ C + ++ C SP + + G K + N
Sbjct: 62 METCDDINECATLSKVSCGKFSDCWNTEGSYDCVC-------SPGYEPVSGAKT--FKNE 112
Query: 61 VTNETKPIDECDIMPQLCKP-GTCHDTPTGFQCGCDHGYEH-DNTSHLCRDVDECSWGRP 118
N + +DEC P+LCK GTC +T + C C G++ +C DV+EC+ G+
Sbjct: 113 SENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQN 172
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDE------CEDVDECGD-QRICDHGD-CRNT 170
PC C+N G+++CRC PG++ P CEDVDEC Q CD C NT
Sbjct: 173 PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNT 232
Query: 171 IGSYRCECKPGYTLRENV 188
+GSY C C+PG+ R +
Sbjct: 233 VGSYSCRCRPGWKPRHGI 250
Score = 103 bits (246), Expect = 4e-21
Identities = 53/130 (40%), Positives = 70/130 (53%), Gaps = 12/130 (9%)
Query: 422 NLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAP-DGLSCVDADECALDPRIC 479
N QD+DEC+ P +C G CVNT GS+ C+C G+ P D C D +EC C
Sbjct: 115 NTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPC 174
Query: 480 GNGT-CSNTRGGYECQCSPGF------TQGPDQT-CVDVDECAEGRASC--TFRCHNTAG 529
+ T C N G Y+C+C PG+ GP+ T C DVDEC+ G+ C + C NT G
Sbjct: 175 HSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVG 234
Query: 530 SFRCTCPYGY 539
S+ C C G+
Sbjct: 235 SYSCRCRPGW 244
Score = 87.0 bits (206), Expect = 3e-16
Identities = 51/129 (39%), Positives = 61/129 (47%), Gaps = 21/129 (16%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYRPAGE---VCADVDECAVRPPPCDQLC 795
DVDEC P LC G + C C PG++ E VC DV+EC PC
Sbjct: 119 DVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSST 178
Query: 796 H--NTDGSYDCLCRTGYEL---DEDGAN---CRDVDECERDTHTCQQ--ICSNTEGSYEC 845
H N GSY C CR G++ +G N C DVDEC H C +C NT GSY C
Sbjct: 179 HCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSC 238
Query: 846 SCEDGYEKR 854
C G++ R
Sbjct: 239 RCRPGWKPR 247
Score = 77.8 bits (183), Expect = 2e-13
Identities = 68/231 (29%), Positives = 96/231 (41%), Gaps = 51/231 (22%)
Query: 252 VGSFRCECAPGYT-----LTADGRNCRDVDECDELPH-PCGRDGNPSCTNTNGGYECSCG 305
V + C C PG++ +T C D++EC L CG+ + C NT G Y+C C
Sbjct: 40 VNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSD--CWNTEGSYDCVCS 97
Query: 306 AGWKLVG----------RRCVDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRF-DKT 353
G++ V C D DEC++ P +C G C N G Y C+C G++F +
Sbjct: 98 PGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPED 157
Query: 354 AAVCVDERKELCYDEWEAGR--CHRARPL--QLARPECCCSEGAAWGRYCERCPAPDSAE 409
VC D +E +G+ CH + + +C C G W P P
Sbjct: 158 PKVCTD------VNECTSGQNPCHSSTHCLNNVGSYQCRCRPG--WQ------PIP---- 199
Query: 410 FMRICQGGMGRPNLT--QDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGY 457
G PN T +D+DEC C C NT GS+ C C G+
Sbjct: 200 ------GSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244
Score = 77.8 bits (183), Expect = 2e-13
Identities = 41/107 (38%), Positives = 50/107 (46%), Gaps = 15/107 (14%)
Query: 761 GRFRCVCGPGYRPAG----------EVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRT 808
G + CVC PGY P C DVDEC P C C NT GSY C C
Sbjct: 90 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 149
Query: 809 GYE-LDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE 852
G++ + ED C DV+EC + C C N GSY+C C G++
Sbjct: 150 GFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 196
Score = 74.1 bits (174), Expect = 2e-12
Identities = 40/108 (37%), Positives = 56/108 (51%), Gaps = 20/108 (18%)
Query: 765 CVCGPGYRPAGEV-------CADVDECA-VRPPPCDQL--CHNTDGSYDCLCRTGYE--- 811
C C PG+ E+ C D++ECA + C + C NT+GSYDC+C GYE
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 812 -----LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE 852
+E C+DVDEC+++ C+ C NT GSY C C G++
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 152
Score = 73.3 bits (172), Expect = 3e-12
Identities = 41/99 (41%), Positives = 53/99 (53%), Gaps = 9/99 (9%)
Query: 548 CRDIDECVQEPRV-CPHA--CENVVGSYICKCPEGYRRTSAPQ----DSENACEDINECE 600
C DI+EC +V C C N GSY C C GY S + +SEN C+D++EC+
Sbjct: 65 CDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQ 124
Query: 601 EQEDLC-SGGVCINTDGSFLCDCDAGFE-PSEDGTDCID 637
+ LC S G C+NT GS+ C C GF+ ED C D
Sbjct: 125 QNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTD 163
Score = 71.3 bits (167), Expect = 1e-11
Identities = 71/256 (27%), Positives = 95/256 (37%), Gaps = 48/256 (18%)
Query: 265 LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR-------RCVD 317
LT G +D C C +D SC N C C G+ C D
Sbjct: 16 LTLPGAETQDSRGCARW---CPQDS--SCVNATA---CRCNPGFSSFSEIITTPMETCDD 67
Query: 318 RDECKELPYVCAG--GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCH 375
+EC L V G +C N G Y C C G+ A +E + C D C
Sbjct: 68 INECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQD---VDECQ 124
Query: 376 RARPLQLARPECCCSEGA---AWGRY-CERCPAPDSAEFMRICQGGMGRPNLTQDLDECR 431
+ P C S G G Y C+ P F I + P + D++EC
Sbjct: 125 Q-------NPRLCKSYGTCVNTLGSYTCQCLPG-----FKFIPED----PKVCTDVNECT 168
Query: 432 VRPDVCVGG-RCVNTDGSFRCECPDGY------VLAPDGLSCVDADECALDPRICGNGT- 483
+ C C+N GS++C C G+ P+ C D DEC+ C + T
Sbjct: 169 SGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTV 228
Query: 484 CSNTRGGYECQCSPGF 499
C NT G Y C+C PG+
Sbjct: 229 CFNTVGSYSCRCRPGW 244
Score = 47.2 bits (107), Expect = 2e-04
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 6/94 (6%)
Query: 556 QEPRVCPHAC---ENVVGSYICKCPEGYRRTSAPQDSE-NACEDINECEEQEDLCSGGV- 610
Q+ R C C + V + C+C G+ S + C+DINEC + G
Sbjct: 24 QDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFS 83
Query: 611 -CINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
C NT+GS+ C C G+EP + TC
Sbjct: 84 DCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTC 117
Score = 34.3 bits (75), Expect = 1.9
Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 7/73 (9%)
Query: 54 PGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCD------HGYEHDNTSHL 106
PG P + +DEC C T C +T + C C HG ++ +
Sbjct: 199 PGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTV 258
Query: 107 CRDVDECSWGRPP 119
C D+ +W PP
Sbjct: 259 CEDMTFSTWTPPP 271
>X94630-1|CAA64333.1| 835|Homo sapiens seven-span transmembrane
protein protein.
Length = 835
Score = 152 bits (368), Expect = 6e-36
Identities = 88/218 (40%), Positives = 110/218 (50%), Gaps = 33/218 (15%)
Query: 120 CRGMAQCVNLPGAFECRCPPGYR-----LTPSLDECEDVDECGDQRICDHG---DCRNTI 171
C + CVN A CRC PG+ +T + C+D++EC G DC NT
Sbjct: 30 CPQNSSCVN---ATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTE 86
Query: 172 GSYRCECKPGY-------TLR---ENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDD 220
GSY C C PGY T + EN C+DVDEC + +C++ GTC N G+Y C C
Sbjct: 87 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 146
Query: 221 GFKAGPNND--CVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTL---TADGRN--- 271
GFK P + C DVNEC G C + C N VGS++C C PG+ + +G N
Sbjct: 147 GFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTV 206
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
C DVDEC H C D + C NT G Y C C GWK
Sbjct: 207 CEDVDECSSGQHQC--DSSTVCFNTVGSYSCRCRPGWK 242
Score = 122 bits (295), Expect = 4e-27
Identities = 73/211 (34%), Positives = 99/211 (46%), Gaps = 27/211 (12%)
Query: 442 CVNTDGSFRCECPDGY-----VLAPDGLSCVDADECALDPRI-CGN-GTCSNTRGGYECQ 494
CVN C C G+ ++ +C D +ECA ++ CG C NT G Y+C
Sbjct: 36 CVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCV 92
Query: 495 CSPG---------FTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFRCTCPYGYA-VA 542
CSPG F + TC DVDEC + C C NT GS+ C C G+ +
Sbjct: 93 CSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIP 152
Query: 543 ADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSEN--ACEDINE 598
D C D++EC C + C N VGSY C+C G++ + N CED++E
Sbjct: 153 EDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDE 212
Query: 599 CEEQEDLC-SGGVCINTDGSFLCDCDAGFEP 628
C + C S VC NT GS+ C C G++P
Sbjct: 213 CSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 243
Score = 122 bits (293), Expect = 7e-27
Identities = 74/233 (31%), Positives = 104/233 (44%), Gaps = 33/233 (14%)
Query: 146 SLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY-------TLRENVCRDVDECSRP 198
+L E D G R C + + + C C PG+ T C D++EC+ P
Sbjct: 14 TLPGAETQDSRGCARWCPQNS--SCVNATACRCNPGFSSFSEIITTPTETCDDINECATP 71
Query: 199 RPV-C-RNGTCENLPGAYLCHCDDG---------FKAGPNNDCVDVNECREGGMVCRN-G 246
V C + C N G+Y C C G FK N C DV+EC++ +C++ G
Sbjct: 72 SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYG 131
Query: 247 RCRNTVGSFRCECAPGYT-LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C NT+GS+ C+C PG+ + D + C DV+EC +PC + C N G Y+C C
Sbjct: 132 TCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPC--HSSTHCLNNVGSYQCRCR 189
Query: 306 AGWKLV--------GRRCVDRDECKELPYVCAGGE-CRNFNGGYVCECPAGWR 349
GW+ + C D DEC + C C N G Y C C GW+
Sbjct: 190 PGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 242
Score = 121 bits (292), Expect = 1e-26
Identities = 70/196 (35%), Positives = 95/196 (48%), Gaps = 25/196 (12%)
Query: 426 DLDECRVRPDVCVG--GRCVNTDGSFRCECPDGYVLAPDGLS--------CVDADECALD 475
D++EC V G C NT+GS+ C C GY + C D DEC +
Sbjct: 64 DINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 123
Query: 476 PRICGN-GTCSNTRGGYECQCSPGFTQGPD--QTCVDVDECAEGRASC--TFRCHNTAGS 530
PR+C + GTC NT G Y CQC PGF P+ + C DV+EC G+ C + C N GS
Sbjct: 124 PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGS 183
Query: 531 FRCTCPYGYAV------AADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYR- 581
++C C G+ + C D+DEC C + C N VGSY C+C G++
Sbjct: 184 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 243
Query: 582 RTSAPQD-SENACEDI 596
R P + + CED+
Sbjct: 244 RHGIPNNQKDTVCEDM 259
Score = 116 bits (280), Expect = 3e-25
Identities = 74/221 (33%), Positives = 100/221 (45%), Gaps = 30/221 (13%)
Query: 38 CPPRGSPAHTALCGEKPG-----EYINPVTNETKPIDECDIMPQL-C-KPGTCHDTPTGF 90
CP S + C PG E I T I+EC ++ C K C +T +
Sbjct: 30 CPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSY 89
Query: 91 QCGCDHGYE--------HDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
C C GYE + + + C+DVDEC C+ CVN G++ C+C PG++
Sbjct: 90 DCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 149
Query: 143 LTPSLDE-CEDVDEC-GDQRICDHG-DCRNTIGSYRCECKPGYT--------LRENVCRD 191
P + C DV+EC Q C C N +GSY+C C+PG+ VC D
Sbjct: 150 FIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCED 209
Query: 192 VDECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAG---PNN 228
VDECS + C + T C N G+Y C C G+K PNN
Sbjct: 210 VDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNN 250
Score = 103 bits (246), Expect = 4e-21
Identities = 53/130 (40%), Positives = 70/130 (53%), Gaps = 12/130 (9%)
Query: 422 NLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAP-DGLSCVDADECALDPRIC 479
N QD+DEC+ P +C G CVNT GS+ C+C G+ P D C D +EC C
Sbjct: 112 NTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPC 171
Query: 480 GNGT-CSNTRGGYECQCSPGF------TQGPDQT-CVDVDECAEGRASC--TFRCHNTAG 529
+ T C N G Y+C+C PG+ GP+ T C DVDEC+ G+ C + C NT G
Sbjct: 172 HSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVG 231
Query: 530 SFRCTCPYGY 539
S+ C C G+
Sbjct: 232 SYSCRCRPGW 241
Score = 87.0 bits (206), Expect = 3e-16
Identities = 51/129 (39%), Positives = 61/129 (47%), Gaps = 21/129 (16%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYRPAGE---VCADVDECAVRPPPCDQLC 795
DVDEC P LC G + C C PG++ E VC DV+EC PC
Sbjct: 116 DVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSST 175
Query: 796 H--NTDGSYDCLCRTGYEL---DEDGAN---CRDVDECERDTHTCQQ--ICSNTEGSYEC 845
H N GSY C CR G++ +G N C DVDEC H C +C NT GSY C
Sbjct: 176 HCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSC 235
Query: 846 SCEDGYEKR 854
C G++ R
Sbjct: 236 RCRPGWKPR 244
Score = 77.8 bits (183), Expect = 2e-13
Identities = 41/107 (38%), Positives = 50/107 (46%), Gaps = 15/107 (14%)
Query: 761 GRFRCVCGPGYRPAG----------EVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRT 808
G + CVC PGY P C DVDEC P C C NT GSY C C
Sbjct: 87 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 146
Query: 809 GYE-LDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE 852
G++ + ED C DV+EC + C C N GSY+C C G++
Sbjct: 147 GFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 193
Score = 75.8 bits (178), Expect = 6e-13
Identities = 69/239 (28%), Positives = 97/239 (40%), Gaps = 54/239 (22%)
Query: 244 RNGRCRNTVGSFRCECAPGYT-----LTADGRNCRDVDECDELPH-PCGRDGNPSCTNTN 297
+N C N C C PG++ +T C D++EC CG+ + C NT
Sbjct: 32 QNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSD--CWNTE 86
Query: 298 GGYECSCGAGWKLVG----------RRCVDRDECKELPYVCAG-GECRNFNGGYVCECPA 346
G Y+C C G++ V C D DEC++ P +C G C N G Y C+C
Sbjct: 87 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 146
Query: 347 GWRF-DKTAAVCVDERKELCYDEWEAGR--CHRARPL--QLARPECCCSEGAAWGRYCER 401
G++F + VC D +E +G+ CH + + +C C G W
Sbjct: 147 GFKFIPEDPKVCTD------VNECTSGQNPCHSSTHCLNNVGSYQCRCRPG--WQ----- 193
Query: 402 CPAPDSAEFMRICQGGMGRPNLT--QDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGY 457
P P G PN T +D+DEC C C NT GS+ C C G+
Sbjct: 194 -PIP----------GSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241
Score = 74.1 bits (174), Expect = 2e-12
Identities = 41/99 (41%), Positives = 53/99 (53%), Gaps = 9/99 (9%)
Query: 548 CRDIDECVQEPRV-CPHA--CENVVGSYICKCPEGYRRTSAPQ----DSENACEDINECE 600
C DI+EC +V C C N GSY C C GY S + +SEN C+D++EC+
Sbjct: 62 CDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQ 121
Query: 601 EQEDLC-SGGVCINTDGSFLCDCDAGFE-PSEDGTDCID 637
+ LC S G C+NT GS+ C C GF+ ED C D
Sbjct: 122 QNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTD 160
Score = 73.7 bits (173), Expect = 2e-12
Identities = 40/108 (37%), Positives = 55/108 (50%), Gaps = 20/108 (18%)
Query: 765 CVCGPGYRPAGEV-------CADVDECAVRPP-PCDQL--CHNTDGSYDCLCRTGYE--- 811
C C PG+ E+ C D++ECA C + C NT+GSYDC+C GYE
Sbjct: 42 CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 101
Query: 812 -----LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE 852
+E C+DVDEC+++ C+ C NT GSY C C G++
Sbjct: 102 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 149
Score = 47.6 bits (108), Expect = 2e-04
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 6/94 (6%)
Query: 556 QEPRVCPHAC---ENVVGSYICKCPEGYRRTSAPQDSEN-ACEDINECEEQEDLCSGGV- 610
Q+ R C C + V + C+C G+ S + C+DINEC + G
Sbjct: 21 QDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFS 80
Query: 611 -CINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
C NT+GS+ C C G+EP + TC
Sbjct: 81 DCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTC 114
Score = 34.3 bits (75), Expect = 1.9
Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 7/73 (9%)
Query: 54 PGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCD------HGYEHDNTSHL 106
PG P + +DEC C T C +T + C C HG ++ +
Sbjct: 196 PGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTV 255
Query: 107 CRDVDECSWGRPP 119
C D+ +W PP
Sbjct: 256 CEDMTFSTWTPPP 268
>U76764-1|AAB36682.1| 835|Homo sapiens CD97 protein.
Length = 835
Score = 152 bits (368), Expect = 6e-36
Identities = 88/218 (40%), Positives = 110/218 (50%), Gaps = 33/218 (15%)
Query: 120 CRGMAQCVNLPGAFECRCPPGYR-----LTPSLDECEDVDECGDQRICDHG---DCRNTI 171
C + CVN A CRC PG+ +T + C+D++EC G DC NT
Sbjct: 30 CPQNSSCVN---ATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTE 86
Query: 172 GSYRCECKPGY-------TLR---ENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDD 220
GSY C C PGY T + EN C+DVDEC + +C++ GTC N G+Y C C
Sbjct: 87 GSYDCVCSPGYEPVSGTKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 146
Query: 221 GFKAGPNND--CVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTL---TADGRN--- 271
GFK P + C DVNEC G C + C N VGS++C C PG+ + +G N
Sbjct: 147 GFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTV 206
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
C DVDEC H C D + C NT G Y C C GWK
Sbjct: 207 CEDVDECSSGQHQC--DSSTVCFNTVGSYSCRCRPGWK 242
Score = 122 bits (295), Expect = 4e-27
Identities = 73/211 (34%), Positives = 99/211 (46%), Gaps = 27/211 (12%)
Query: 442 CVNTDGSFRCECPDGY-----VLAPDGLSCVDADECALDPRI-CGN-GTCSNTRGGYECQ 494
CVN C C G+ ++ +C D +ECA ++ CG C NT G Y+C
Sbjct: 36 CVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCV 92
Query: 495 CSPG---------FTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFRCTCPYGYA-VA 542
CSPG F + TC DVDEC + C C NT GS+ C C G+ +
Sbjct: 93 CSPGYEPVSGTKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIP 152
Query: 543 ADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSEN--ACEDINE 598
D C D++EC C + C N VGSY C+C G++ + N CED++E
Sbjct: 153 EDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDE 212
Query: 599 CEEQEDLC-SGGVCINTDGSFLCDCDAGFEP 628
C + C S VC NT GS+ C C G++P
Sbjct: 213 CSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 243
Score = 122 bits (293), Expect = 7e-27
Identities = 74/233 (31%), Positives = 104/233 (44%), Gaps = 33/233 (14%)
Query: 146 SLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY-------TLRENVCRDVDECSRP 198
+L E D G R C + + + C C PG+ T C D++EC+ P
Sbjct: 14 TLPGAETQDSRGCARWCPQNS--SCVNATACRCNPGFSSFSEIITTPTETCDDINECATP 71
Query: 199 RPV-C-RNGTCENLPGAYLCHCDDG---------FKAGPNNDCVDVNECREGGMVCRN-G 246
V C + C N G+Y C C G FK N C DV+EC++ +C++ G
Sbjct: 72 SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGTKTFKNESENTCQDVDECQQNPRLCKSYG 131
Query: 247 RCRNTVGSFRCECAPGYT-LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C NT+GS+ C+C PG+ + D + C DV+EC +PC + C N G Y+C C
Sbjct: 132 TCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPC--HSSTHCLNNVGSYQCRCR 189
Query: 306 AGWKLV--------GRRCVDRDECKELPYVCAGGE-CRNFNGGYVCECPAGWR 349
GW+ + C D DEC + C C N G Y C C GW+
Sbjct: 190 PGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 242
Score = 120 bits (290), Expect = 2e-26
Identities = 70/196 (35%), Positives = 95/196 (48%), Gaps = 25/196 (12%)
Query: 426 DLDECRVRPDVCVG--GRCVNTDGSFRCECPDGYVLAPDGLS--------CVDADECALD 475
D++EC V G C NT+GS+ C C GY + C D DEC +
Sbjct: 64 DINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGTKTFKNESENTCQDVDECQQN 123
Query: 476 PRICGN-GTCSNTRGGYECQCSPGFTQGPD--QTCVDVDECAEGRASC--TFRCHNTAGS 530
PR+C + GTC NT G Y CQC PGF P+ + C DV+EC G+ C + C N GS
Sbjct: 124 PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGS 183
Query: 531 FRCTCPYGYAV------AADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYR- 581
++C C G+ + C D+DEC C + C N VGSY C+C G++
Sbjct: 184 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 243
Query: 582 RTSAPQD-SENACEDI 596
R P + + CED+
Sbjct: 244 RHGIPNNQKDTVCEDM 259
Score = 116 bits (280), Expect = 3e-25
Identities = 74/221 (33%), Positives = 100/221 (45%), Gaps = 30/221 (13%)
Query: 38 CPPRGSPAHTALCGEKPG-----EYINPVTNETKPIDECDIMPQL-C-KPGTCHDTPTGF 90
CP S + C PG E I T I+EC ++ C K C +T +
Sbjct: 30 CPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSY 89
Query: 91 QCGCDHGYE--------HDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
C C GYE + + + C+DVDEC C+ CVN G++ C+C PG++
Sbjct: 90 DCVCSPGYEPVSGTKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 149
Query: 143 LTPSLDE-CEDVDEC-GDQRICDHG-DCRNTIGSYRCECKPGYT--------LRENVCRD 191
P + C DV+EC Q C C N +GSY+C C+PG+ VC D
Sbjct: 150 FIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCED 209
Query: 192 VDECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAG---PNN 228
VDECS + C + T C N G+Y C C G+K PNN
Sbjct: 210 VDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNN 250
Score = 103 bits (246), Expect = 4e-21
Identities = 53/130 (40%), Positives = 70/130 (53%), Gaps = 12/130 (9%)
Query: 422 NLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAP-DGLSCVDADECALDPRIC 479
N QD+DEC+ P +C G CVNT GS+ C+C G+ P D C D +EC C
Sbjct: 112 NTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPC 171
Query: 480 GNGT-CSNTRGGYECQCSPGF------TQGPDQT-CVDVDECAEGRASC--TFRCHNTAG 529
+ T C N G Y+C+C PG+ GP+ T C DVDEC+ G+ C + C NT G
Sbjct: 172 HSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVG 231
Query: 530 SFRCTCPYGY 539
S+ C C G+
Sbjct: 232 SYSCRCRPGW 241
Score = 87.0 bits (206), Expect = 3e-16
Identities = 51/129 (39%), Positives = 61/129 (47%), Gaps = 21/129 (16%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYRPAGE---VCADVDECAVRPPPCDQLC 795
DVDEC P LC G + C C PG++ E VC DV+EC PC
Sbjct: 116 DVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSST 175
Query: 796 H--NTDGSYDCLCRTGYEL---DEDGAN---CRDVDECERDTHTCQQ--ICSNTEGSYEC 845
H N GSY C CR G++ +G N C DVDEC H C +C NT GSY C
Sbjct: 176 HCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSC 235
Query: 846 SCEDGYEKR 854
C G++ R
Sbjct: 236 RCRPGWKPR 244
Score = 77.8 bits (183), Expect = 2e-13
Identities = 41/107 (38%), Positives = 50/107 (46%), Gaps = 15/107 (14%)
Query: 761 GRFRCVCGPGYRPAG----------EVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRT 808
G + CVC PGY P C DVDEC P C C NT GSY C C
Sbjct: 87 GSYDCVCSPGYEPVSGTKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 146
Query: 809 GYE-LDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE 852
G++ + ED C DV+EC + C C N GSY+C C G++
Sbjct: 147 GFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 193
Score = 75.8 bits (178), Expect = 6e-13
Identities = 69/239 (28%), Positives = 97/239 (40%), Gaps = 54/239 (22%)
Query: 244 RNGRCRNTVGSFRCECAPGYT-----LTADGRNCRDVDECDELPH-PCGRDGNPSCTNTN 297
+N C N C C PG++ +T C D++EC CG+ + C NT
Sbjct: 32 QNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSD--CWNTE 86
Query: 298 GGYECSCGAGWKLVG----------RRCVDRDECKELPYVCAG-GECRNFNGGYVCECPA 346
G Y+C C G++ V C D DEC++ P +C G C N G Y C+C
Sbjct: 87 GSYDCVCSPGYEPVSGTKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 146
Query: 347 GWRF-DKTAAVCVDERKELCYDEWEAGR--CHRARPL--QLARPECCCSEGAAWGRYCER 401
G++F + VC D +E +G+ CH + + +C C G W
Sbjct: 147 GFKFIPEDPKVCTD------VNECTSGQNPCHSSTHCLNNVGSYQCRCRPG--WQ----- 193
Query: 402 CPAPDSAEFMRICQGGMGRPNLT--QDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGY 457
P P G PN T +D+DEC C C NT GS+ C C G+
Sbjct: 194 -PIP----------GSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241
Score = 74.1 bits (174), Expect = 2e-12
Identities = 41/99 (41%), Positives = 53/99 (53%), Gaps = 9/99 (9%)
Query: 548 CRDIDECVQEPRV-CPHA--CENVVGSYICKCPEGYRRTSAPQ----DSENACEDINECE 600
C DI+EC +V C C N GSY C C GY S + +SEN C+D++EC+
Sbjct: 62 CDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGTKTFKNESENTCQDVDECQ 121
Query: 601 EQEDLC-SGGVCINTDGSFLCDCDAGFE-PSEDGTDCID 637
+ LC S G C+NT GS+ C C GF+ ED C D
Sbjct: 122 QNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTD 160
Score = 73.7 bits (173), Expect = 2e-12
Identities = 40/108 (37%), Positives = 55/108 (50%), Gaps = 20/108 (18%)
Query: 765 CVCGPGYRPAGEV-------CADVDECAVRPP-PCDQL--CHNTDGSYDCLCRTGYE--- 811
C C PG+ E+ C D++ECA C + C NT+GSYDC+C GYE
Sbjct: 42 CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 101
Query: 812 -----LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE 852
+E C+DVDEC+++ C+ C NT GSY C C G++
Sbjct: 102 GTKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 149
Score = 46.8 bits (106), Expect = 3e-04
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 6/94 (6%)
Query: 556 QEPRVCPHAC---ENVVGSYICKCPEGYRRTSAPQDSEN-ACEDINECEEQEDLCSGGV- 610
Q+ R C C + V + C+C G+ S + C+DINEC + G
Sbjct: 21 QDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFS 80
Query: 611 -CINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
C NT+GS+ C C G+EP + TC
Sbjct: 81 DCWNTEGSYDCVCSPGYEPVSGTKTFKNESENTC 114
Score = 34.3 bits (75), Expect = 1.9
Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 7/73 (9%)
Query: 54 PGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCD------HGYEHDNTSHL 106
PG P + +DEC C T C +T + C C HG ++ +
Sbjct: 196 PGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTV 255
Query: 107 CRDVDECSWGRPP 119
C D+ +W PP
Sbjct: 256 CEDMTFSTWTPPP 268
>AK131562-1|BAD18695.1| 867|Homo sapiens protein ( Homo sapiens
cDNA FLJ16811 fis, clone THYMU3024602, highly similar
to Cell surface glycoprotein EMR1 precursor. ).
Length = 867
Score = 152 bits (368), Expect = 6e-36
Identities = 78/212 (36%), Positives = 105/212 (49%), Gaps = 27/212 (12%)
Query: 120 CRGMAQCVNLPGAFECRCPPGYRLTPSLDE-------CEDVDECGDQRIC-DHGDCRNTI 171
C A C N ++ C C G+ + + C+D++EC +C +H DC N++
Sbjct: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDINECLTSSVCPEHSDCVNSM 100
Query: 172 GSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA------- 224
GSY C C+ G+ R + C DVDEC+ PR + TC N G Y C C+ GF++
Sbjct: 101 GSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSF 160
Query: 225 -GPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGY-------TLTADGRNCRDVD 276
G C D++EC E M N C NT GS+ C C PG+ T G CRD+D
Sbjct: 161 QGLKASCEDIDECTE--MCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDID 218
Query: 277 ECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
EC + P CG N CTN G Y C C AG+
Sbjct: 219 ECRQDPSTCG--PNSICTNALGSYSCGCIAGF 248
Score = 137 bits (332), Expect = 1e-31
Identities = 79/236 (33%), Positives = 107/236 (45%), Gaps = 31/236 (13%)
Query: 82 TCHDTPTGFQCGCDHGYEHDN-TSHL------CRDVDECSWGRPPCRGMAQCVNLPGAFE 134
TC +T + C C G+ N +H C+D++EC C + CVN G++
Sbjct: 46 TCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDINECLTSSV-CPEHSDCVNSMGSYS 104
Query: 135 CRCPPGYRLTPSLDECEDVDECGDQRIC-DHGDCRNTIGSYRCECKPGYTLREN------ 187
C C G+ S CEDVDEC D R C +H C NT+G+Y C C PG+
Sbjct: 105 CSCQVGFISRNST--CEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQG 162
Query: 188 ---VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA--GPNN------DCVDVNEC 236
C D+DEC+ P+ N TC N PG+Y C C GF G N +C D++EC
Sbjct: 163 LKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDEC 220
Query: 237 REGGMVCR-NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNP 291
R+ C N C N +GS+ C C G+ +G C + C D P
Sbjct: 221 RQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKEDVIP 276
Score = 128 bits (309), Expect = 8e-29
Identities = 73/214 (34%), Positives = 103/214 (48%), Gaps = 27/214 (12%)
Query: 442 CVNTDGSFRCECPDGYVLA-------PDGLSCVDADECALDPRICG-NGTCSNTRGGYEC 493
C NT S+ C C G++ + G+ C D +EC L +C + C N+ G Y C
Sbjct: 47 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDINEC-LTSSVCPEHSDCVNSMGSYSC 105
Query: 494 QCSPGFTQGPDQTCVDVDECAEGRASCTF-RCHNTAGSFRCTCPYGYAVAADGV------ 546
C GF + TC DVDECA+ RA C+NT G++ C C G+ ++ +
Sbjct: 106 SCQVGFI-SRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLK 164
Query: 547 -HCRDIDECVQEPRVCP--HACENVVGSYICKCPEGYRRTSAP---QDSENACEDINECE 600
C DIDEC + +CP C N GSY C C G+ ++ D C DI+EC
Sbjct: 165 ASCEDIDECTE---MCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECR 221
Query: 601 EQEDLCS-GGVCINTDGSFLCDCDAGFEPSEDGT 633
+ C +C N GS+ C C AGF P+ +G+
Sbjct: 222 QDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGS 255
Score = 128 bits (309), Expect = 8e-29
Identities = 77/199 (38%), Positives = 105/199 (52%), Gaps = 27/199 (13%)
Query: 425 QDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NG 482
+D++EC + VC CVN+ GS+ C C G++ +C D DECA DPR C +
Sbjct: 79 KDINEC-LTSSVCPEHSDCVNSMGSYSCSCQVGFISRNS--TCEDVDECA-DPRACPEHA 134
Query: 483 TCSNTRGGYECQCSPGFT--------QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCT 534
TC+NT G Y C C+PGF QG +C D+DEC E C NT GS+ CT
Sbjct: 135 TCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTE-MCPINSTCTNTPGSYFCT 193
Query: 535 CPYGYA-------VAADGVHCRDIDECVQEPRVC-PHA-CENVVGSYICKCPEGYRRT-- 583
C G+A GV CRDIDEC Q+P C P++ C N +GSY C C G+
Sbjct: 194 CHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPE 253
Query: 584 SAPQDSENACEDI-NECEE 601
+ +D +C+ + +C+E
Sbjct: 254 GSQKDGNFSCQRVLFKCKE 272
Score = 109 bits (261), Expect = 5e-23
Identities = 64/179 (35%), Positives = 87/179 (48%), Gaps = 20/179 (11%)
Query: 475 DPRIC-GNGTCSNTRGGYECQCSPGFTQG--------PDQTCVDVDECAEGRASCTFR-C 524
D +C TC+NT Y C C GF P C D++EC C
Sbjct: 37 DSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDINECLTSSVCPEHSDC 96
Query: 525 HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCP-HA-CENVVGSYICKCPEGYRR 582
N+ GS+ C+C G+ ++ + C D+DEC +PR CP HA C N VG+Y C C G+
Sbjct: 97 VNSMGSYSCSCQVGF-ISRNST-CEDVDECA-DPRACPEHATCNNTVGNYSCFCNPGFES 153
Query: 583 TSAP---QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDR 638
+S Q + +CEDI+EC E + S C NT GS+ C C GF PS + D+
Sbjct: 154 SSGHLSFQGLKASCEDIDECTEMCPINS--TCTNTPGSYFCTCHPGFAPSNGQLNFTDQ 210
Score = 97.1 bits (231), Expect = 2e-19
Identities = 65/199 (32%), Positives = 90/199 (45%), Gaps = 26/199 (13%)
Query: 66 KPIDECDIMPQLC-KPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMA 124
K I+EC + +C + C ++ + C C G+ N++ C DVDEC+ R C A
Sbjct: 79 KDINEC-LTSSVCPEHSDCVNSMGSYSCSCQVGFISRNST--CEDVDECADPR-ACPEHA 134
Query: 125 QCVNLPGAFECRCPPGYRLTPS-------LDECEDVDECGDQRICD-HGDCRNTIGSYRC 176
C N G + C C PG+ + CED+DEC + +C + C NT GSY C
Sbjct: 135 TCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTE--MCPINSTCTNTPGSYFC 192
Query: 177 ECKPG---------YTLRENVCRDVDECSRPRPVC-RNGTCENLPGAYLCHCDDGFKAGP 226
C PG +T + CRD+DEC + C N C N G+Y C C GF P
Sbjct: 193 TCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNP 252
Query: 227 NNDCVDVN-ECREGGMVCR 244
D N C+ C+
Sbjct: 253 EGSQKDGNFSCQRVLFKCK 271
Score = 89.0 bits (211), Expect = 6e-17
Identities = 69/240 (28%), Positives = 97/240 (40%), Gaps = 28/240 (11%)
Query: 234 NECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRN--------CRDVDECDELPHPC 285
N CR+ + C NTV S+ C C G+ L+++G+N C+D++EC C
Sbjct: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGF-LSSNGQNHFKDPGVRCKDINEC-LTSSVC 90
Query: 286 GRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVC-AGGECRNFNGGYVCEC 344
+ C N+ G Y CSC G+ C D DEC + P C C N G Y C C
Sbjct: 91 PEHSD--CVNSMGSYSCSCQVGFISRNSTCEDVDECAD-PRACPEHATCNNTVGNYSCFC 147
Query: 345 PAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPA 404
G+ + + K C D C P+ C + ++ C A
Sbjct: 148 NPGFE-SSSGHLSFQGLKASCED---IDECTEMCPIN----STCTNTPGSYFCTCHPGFA 199
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDG 463
P + + QG R D+DECR P C C N GS+ C C G+ P+G
Sbjct: 200 PSNGQLNFTDQGVECR-----DIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 254
Score = 81.8 bits (193), Expect = 9e-15
Identities = 49/130 (37%), Positives = 61/130 (46%), Gaps = 26/130 (20%)
Query: 747 DVDECA---AIP--GLC--APGRFRCVCGPGYRPA-GEV--------CADVDECAVRPPP 790
DVDECA A P C G + C C PG+ + G + C D+DEC P
Sbjct: 120 DVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT-EMCP 178
Query: 791 CDQLCHNTDGSYDCLCRTGY-------ELDEDGANCRDVDECERDTHTC--QQICSNTEG 841
+ C NT GSY C C G+ + G CRD+DEC +D TC IC+N G
Sbjct: 179 INSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALG 238
Query: 842 SYECSCEDGY 851
SY C C G+
Sbjct: 239 SYSCGCIAGF 248
Score = 76.2 bits (179), Expect = 5e-13
Identities = 41/101 (40%), Positives = 51/101 (50%), Gaps = 13/101 (12%)
Query: 761 GRFRCVCGPGYRPAGEVCADVDECA-VRPPPCDQLCHNTDGSYDCLCRTGYE-----LDE 814
G + C C G+ C DVDECA R P C+NT G+Y C C G+E L
Sbjct: 101 GSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSF 160
Query: 815 DG--ANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGY 851
G A+C D+DEC T C C+NT GSY C+C G+
Sbjct: 161 QGLKASCEDIDEC---TEMCPINSTCTNTPGSYFCTCHPGF 198
Score = 62.5 bits (145), Expect = 6e-09
Identities = 33/87 (37%), Positives = 46/87 (52%), Gaps = 10/87 (11%)
Query: 771 YRPAGEVCADVDEC---AVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECER 827
++ G C D++EC +V P D C N+ GSY C C+ G+ + C DVDEC
Sbjct: 71 FKDPGVRCKDINECLTSSVCPEHSD--CVNSMGSYSCSCQVGFI--SRNSTCEDVDECA- 125
Query: 828 DTHTCQQ--ICSNTEGSYECSCEDGYE 852
D C + C+NT G+Y C C G+E
Sbjct: 126 DPRACPEHATCNNTVGNYSCFCNPGFE 152
Score = 58.0 bits (134), Expect = 1e-07
Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 16/104 (15%)
Query: 747 DVDECAA---IPGLCA--PGRFRCVCGPGYRPA---------GEVCADVDECAVRPPPC- 791
D+DEC I C PG + C C PG+ P+ G C D+DEC P C
Sbjct: 169 DIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCG 228
Query: 792 -DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ 834
+ +C N GSY C C G+ + +G+ C+R C++
Sbjct: 229 PNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKE 272
Score = 52.4 bits (120), Expect = 7e-06
Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 15/93 (16%)
Query: 775 GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY-------ELDEDGANCRDVDECER 827
G C D C P C NT SY C C+ G+ + G C+D++EC
Sbjct: 32 GNNCRDSTLC-----PAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDINECLT 86
Query: 828 DTHTCQQI--CSNTEGSYECSCEDGYEKRGDAC 858
+ C + C N+ GSY CSC+ G+ R C
Sbjct: 87 SS-VCPEHSDCVNSMGSYSCSCQVGFISRNSTC 118
>AB065966-1|BAC06178.1| 837|Homo sapiens seven transmembrane helix
receptor protein.
Length = 837
Score = 152 bits (368), Expect = 6e-36
Identities = 88/218 (40%), Positives = 110/218 (50%), Gaps = 33/218 (15%)
Query: 120 CRGMAQCVNLPGAFECRCPPGYR-----LTPSLDECEDVDECGDQRICDHG---DCRNTI 171
C + CVN A CRC PG+ +T + C+D++EC G DC NT
Sbjct: 32 CPQNSSCVN---ATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTE 88
Query: 172 GSYRCECKPGY-------TLR---ENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDD 220
GSY C C PGY T + EN C+DVDEC + +C++ GTC N G+Y C C
Sbjct: 89 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 148
Query: 221 GFKAGPNND--CVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTL---TADGRN--- 271
GFK P + C DVNEC G C + C N VGS++C C PG+ + +G N
Sbjct: 149 GFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTV 208
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
C DVDEC H C D + C NT G Y C C GWK
Sbjct: 209 CEDVDECSSGQHQC--DSSTVCFNTVGSYSCRCRPGWK 244
Score = 122 bits (295), Expect = 4e-27
Identities = 73/211 (34%), Positives = 99/211 (46%), Gaps = 27/211 (12%)
Query: 442 CVNTDGSFRCECPDGY-----VLAPDGLSCVDADECALDPRI-CGN-GTCSNTRGGYECQ 494
CVN C C G+ ++ +C D +ECA ++ CG C NT G Y+C
Sbjct: 38 CVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCV 94
Query: 495 CSPG---------FTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFRCTCPYGYA-VA 542
CSPG F + TC DVDEC + C C NT GS+ C C G+ +
Sbjct: 95 CSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIP 154
Query: 543 ADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSEN--ACEDINE 598
D C D++EC C + C N VGSY C+C G++ + N CED++E
Sbjct: 155 EDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDE 214
Query: 599 CEEQEDLC-SGGVCINTDGSFLCDCDAGFEP 628
C + C S VC NT GS+ C C G++P
Sbjct: 215 CSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 245
Score = 122 bits (293), Expect = 7e-27
Identities = 74/233 (31%), Positives = 104/233 (44%), Gaps = 33/233 (14%)
Query: 146 SLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY-------TLRENVCRDVDECSRP 198
+L E D G R C + + + C C PG+ T C D++EC+ P
Sbjct: 16 TLPGAETQDSRGCARWCPQNS--SCVNATACRCNPGFSSFSEIITTPTETCDDINECATP 73
Query: 199 RPV-C-RNGTCENLPGAYLCHCDDG---------FKAGPNNDCVDVNECREGGMVCRN-G 246
V C + C N G+Y C C G FK N C DV+EC++ +C++ G
Sbjct: 74 SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYG 133
Query: 247 RCRNTVGSFRCECAPGYT-LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C NT+GS+ C+C PG+ + D + C DV+EC +PC + C N G Y+C C
Sbjct: 134 TCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPC--HSSTHCLNNVGSYQCRCR 191
Query: 306 AGWKLV--------GRRCVDRDECKELPYVCAGGE-CRNFNGGYVCECPAGWR 349
GW+ + C D DEC + C C N G Y C C GW+
Sbjct: 192 PGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 244
Score = 121 bits (292), Expect = 1e-26
Identities = 70/196 (35%), Positives = 95/196 (48%), Gaps = 25/196 (12%)
Query: 426 DLDECRVRPDVCVG--GRCVNTDGSFRCECPDGYVLAPDGLS--------CVDADECALD 475
D++EC V G C NT+GS+ C C GY + C D DEC +
Sbjct: 66 DINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 125
Query: 476 PRICGN-GTCSNTRGGYECQCSPGFTQGPD--QTCVDVDECAEGRASC--TFRCHNTAGS 530
PR+C + GTC NT G Y CQC PGF P+ + C DV+EC G+ C + C N GS
Sbjct: 126 PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGS 185
Query: 531 FRCTCPYGYAV------AADGVHCRDIDECVQEPRVCPHA--CENVVGSYICKCPEGYR- 581
++C C G+ + C D+DEC C + C N VGSY C+C G++
Sbjct: 186 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 245
Query: 582 RTSAPQD-SENACEDI 596
R P + + CED+
Sbjct: 246 RHGIPNNQKDTVCEDM 261
Score = 116 bits (280), Expect = 3e-25
Identities = 74/221 (33%), Positives = 100/221 (45%), Gaps = 30/221 (13%)
Query: 38 CPPRGSPAHTALCGEKPG-----EYINPVTNETKPIDECDIMPQL-C-KPGTCHDTPTGF 90
CP S + C PG E I T I+EC ++ C K C +T +
Sbjct: 32 CPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSY 91
Query: 91 QCGCDHGYE--------HDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
C C GYE + + + C+DVDEC C+ CVN G++ C+C PG++
Sbjct: 92 DCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 151
Query: 143 LTPSLDE-CEDVDEC-GDQRICDHG-DCRNTIGSYRCECKPGYT--------LRENVCRD 191
P + C DV+EC Q C C N +GSY+C C+PG+ VC D
Sbjct: 152 FIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCED 211
Query: 192 VDECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAG---PNN 228
VDECS + C + T C N G+Y C C G+K PNN
Sbjct: 212 VDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNN 252
Score = 103 bits (246), Expect = 4e-21
Identities = 53/130 (40%), Positives = 70/130 (53%), Gaps = 12/130 (9%)
Query: 422 NLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAP-DGLSCVDADECALDPRIC 479
N QD+DEC+ P +C G CVNT GS+ C+C G+ P D C D +EC C
Sbjct: 114 NTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPC 173
Query: 480 GNGT-CSNTRGGYECQCSPGF------TQGPDQT-CVDVDECAEGRASC--TFRCHNTAG 529
+ T C N G Y+C+C PG+ GP+ T C DVDEC+ G+ C + C NT G
Sbjct: 174 HSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVG 233
Query: 530 SFRCTCPYGY 539
S+ C C G+
Sbjct: 234 SYSCRCRPGW 243
Score = 87.0 bits (206), Expect = 3e-16
Identities = 51/129 (39%), Positives = 61/129 (47%), Gaps = 21/129 (16%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYRPAGE---VCADVDECAVRPPPCDQLC 795
DVDEC P LC G + C C PG++ E VC DV+EC PC
Sbjct: 118 DVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSST 177
Query: 796 H--NTDGSYDCLCRTGYEL---DEDGAN---CRDVDECERDTHTCQQ--ICSNTEGSYEC 845
H N GSY C CR G++ +G N C DVDEC H C +C NT GSY C
Sbjct: 178 HCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSC 237
Query: 846 SCEDGYEKR 854
C G++ R
Sbjct: 238 RCRPGWKPR 246
Score = 77.8 bits (183), Expect = 2e-13
Identities = 41/107 (38%), Positives = 50/107 (46%), Gaps = 15/107 (14%)
Query: 761 GRFRCVCGPGYRPAG----------EVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRT 808
G + CVC PGY P C DVDEC P C C NT GSY C C
Sbjct: 89 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 148
Query: 809 GYE-LDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE 852
G++ + ED C DV+EC + C C N GSY+C C G++
Sbjct: 149 GFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 195
Score = 75.8 bits (178), Expect = 6e-13
Identities = 69/239 (28%), Positives = 97/239 (40%), Gaps = 54/239 (22%)
Query: 244 RNGRCRNTVGSFRCECAPGYT-----LTADGRNCRDVDECDELPH-PCGRDGNPSCTNTN 297
+N C N C C PG++ +T C D++EC CG+ + C NT
Sbjct: 34 QNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSD--CWNTE 88
Query: 298 GGYECSCGAGWKLVG----------RRCVDRDECKELPYVCAG-GECRNFNGGYVCECPA 346
G Y+C C G++ V C D DEC++ P +C G C N G Y C+C
Sbjct: 89 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 148
Query: 347 GWRF-DKTAAVCVDERKELCYDEWEAGR--CHRARPL--QLARPECCCSEGAAWGRYCER 401
G++F + VC D +E +G+ CH + + +C C G W
Sbjct: 149 GFKFIPEDPKVCTD------VNECTSGQNPCHSSTHCLNNVGSYQCRCRPG--WQ----- 195
Query: 402 CPAPDSAEFMRICQGGMGRPNLT--QDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGY 457
P P G PN T +D+DEC C C NT GS+ C C G+
Sbjct: 196 -PIP----------GSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 243
Score = 74.1 bits (174), Expect = 2e-12
Identities = 41/99 (41%), Positives = 53/99 (53%), Gaps = 9/99 (9%)
Query: 548 CRDIDECVQEPRV-CPHA--CENVVGSYICKCPEGYRRTSAPQ----DSENACEDINECE 600
C DI+EC +V C C N GSY C C GY S + +SEN C+D++EC+
Sbjct: 64 CDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQ 123
Query: 601 EQEDLC-SGGVCINTDGSFLCDCDAGFE-PSEDGTDCID 637
+ LC S G C+NT GS+ C C GF+ ED C D
Sbjct: 124 QNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTD 162
Score = 73.7 bits (173), Expect = 2e-12
Identities = 40/108 (37%), Positives = 55/108 (50%), Gaps = 20/108 (18%)
Query: 765 CVCGPGYRPAGEV-------CADVDECAVRPP-PCDQL--CHNTDGSYDCLCRTGYE--- 811
C C PG+ E+ C D++ECA C + C NT+GSYDC+C GYE
Sbjct: 44 CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 103
Query: 812 -----LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE 852
+E C+DVDEC+++ C+ C NT GSY C C G++
Sbjct: 104 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 151
Score = 47.6 bits (108), Expect = 2e-04
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 6/94 (6%)
Query: 556 QEPRVCPHAC---ENVVGSYICKCPEGYRRTSAPQDSEN-ACEDINECEEQEDLCSGGV- 610
Q+ R C C + V + C+C G+ S + C+DINEC + G
Sbjct: 23 QDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFS 82
Query: 611 -CINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
C NT+GS+ C C G+EP + TC
Sbjct: 83 DCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTC 116
Score = 34.3 bits (75), Expect = 1.9
Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 7/73 (9%)
Query: 54 PGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCD------HGYEHDNTSHL 106
PG P + +DEC C T C +T + C C HG ++ +
Sbjct: 198 PGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTV 257
Query: 107 CRDVDECSWGRPP 119
C D+ +W PP
Sbjct: 258 CEDMTFSTWTPPP 270
>D89629-1|BAB46925.1| 815|Homo sapiens cerebral protein-12 protein.
Length = 815
Score = 149 bits (361), Expect = 4e-35
Identities = 90/257 (35%), Positives = 115/257 (44%), Gaps = 24/257 (9%)
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYE---HDNTSHLCRDVDECSWGRPPCRG 122
K D C + C + C C G+ DN C D+DEC+ GR CR
Sbjct: 395 KGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNA--YCEDIDECAEGRHYCRE 452
Query: 123 MAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GDQRICDHGD-CRNTIGSYRCECKP 180
CVN PG+F C C GY C + DEC +Q CD C NT+G + C CKP
Sbjct: 453 NTMCVNTPGSFMCICKTGYIRIDDY-SCTEHDECITNQHNCDENALCFNTVGGHNCVCKP 511
Query: 181 GYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGG 240
GYT C+ C + CRNG A +C C GF GP+ + D++EC +G
Sbjct: 512 GYTGNGTTCKAF--C---KDGCRNGGA--CIAANVCACPQGF-TGPSCE-TDIDECSDGF 562
Query: 241 MVC-RNGRCRNTVGSFRCECAPGY----TLTADGRNCRDVDECDELPHPCGRDGNPSCTN 295
+ C C N G + CEC GY + G +C D+DEC H C D C N
Sbjct: 563 VQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCAND--TICFN 620
Query: 296 TNGGYECSCGAGWKLVG 312
+GGY+C C G G
Sbjct: 621 LDGGYDCRCPHGKNCTG 637
Score = 125 bits (302), Expect = 6e-28
Identities = 88/255 (34%), Positives = 115/255 (45%), Gaps = 28/255 (10%)
Query: 106 LCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR-LTPSLDECEDVDECGDQR-IC- 162
+C+ D CS R C + C NL C C G+R L CED+DEC + R C
Sbjct: 393 VCKGYDFCS-ERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCR 451
Query: 163 DHGDCRNTIGSYRCECKPGYT-LRENVCRDVDECSRPRPVC-RNGTCENLPGAYLCHCDD 220
++ C NT GS+ C CK GY + + C + DEC + C N C N G + C C
Sbjct: 452 ENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKP 511
Query: 221 GFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECD 279
G+ G C C++G CRNG + + C C G+T G +C D+DEC
Sbjct: 512 GY-TGNGTTCKAF--CKDG---CRNGGA--CIAANVCACPQGFT----GPSCETDIDECS 559
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGW------KLVGRRCVDRDECKELPYVCAGGE- 332
+ C D +C N G Y C C G+ G C D DEC + CA
Sbjct: 560 DGFVQC--DSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTI 617
Query: 333 CRNFNGGYVCECPAG 347
C N +GGY C CP G
Sbjct: 618 CFNLDGGYDCRCPHG 632
Score = 123 bits (296), Expect = 3e-27
Identities = 76/210 (36%), Positives = 93/210 (44%), Gaps = 24/210 (11%)
Query: 425 QDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NG 482
+D+DEC C CVNT GSF C C GY+ D SC + DEC + C N
Sbjct: 438 EDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDD-YSCTEHDECITNQHNCDENA 496
Query: 483 TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR---CTCPYGY 539
C NT GG+ C C PG+T G TC +A C C N C CP G+
Sbjct: 497 LCFNTVGGHNCVCKPGYT-GNGTTC---------KAFCKDGCRNGGACIAANVCACPQGF 546
Query: 540 AVAADGVHCR-DIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENACEDI 596
G C DIDEC C C N+ G Y C+C +GY S +CEDI
Sbjct: 547 T----GPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDI 602
Query: 597 NECEEQEDLCSGG-VCINTDGSFLCDCDAG 625
+EC C+ +C N DG + C C G
Sbjct: 603 DECGTGRHSCANDTICFNLDGGYDCRCPHG 632
Score = 110 bits (265), Expect = 2e-23
Identities = 74/223 (33%), Positives = 103/223 (46%), Gaps = 25/223 (11%)
Query: 137 CPPGYRLTPS---LDECEDVDECGDQRIC-DHGDCRNTIGSYRCECKPGY-TLREN--VC 189
CP +++T S C+ D C ++ C ++ CRN C C+ G+ LRE+ C
Sbjct: 378 CPESHQITLSHSCCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYC 437
Query: 190 RDVDECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC-RNGR 247
D+DEC+ R CR T C N PG+++C C G+ + C + +EC C N
Sbjct: 438 EDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENAL 497
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
C NTVG C C PGYT +G C+ C + C G +C N C+C G
Sbjct: 498 CFNTVGGHNCVCKPGYT--GNGTTCKAF--CKD---GCRNGG--ACIAAN---VCACPQG 545
Query: 308 WKLVGRRC-VDRDECKELPYVC-AGGECRNFNGGYVCECPAGW 348
+ G C D DEC + C + C N G Y CEC G+
Sbjct: 546 F--TGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGY 586
Score = 103 bits (247), Expect = 3e-21
Identities = 69/247 (27%), Positives = 98/247 (39%), Gaps = 29/247 (11%)
Query: 402 CPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGY-VLA 460
CPA D E +I + + D C R + C N + C C DG+ L
Sbjct: 373 CPALDCPESHQITLSH-SCCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALR 431
Query: 461 PDGLSCVDADECALDPRICGNGT-CSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS 519
D C D DECA C T C NT G + C C G+ + D +C + DEC + +
Sbjct: 432 EDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHN 491
Query: 520 CTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN---VVGSYIC 574
C C NT G C C GY +G C+ C C N + + +C
Sbjct: 492 CDENALCFNTVGGHNCVCKPGYT--GNGTTCKAF---------CKDGCRNGGACIAANVC 540
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP----SE 630
CP+G+ S D + + +C+ + + CIN G + C+C G+ S
Sbjct: 541 ACPQGFTGPSCETDIDECSDGFVQCDSRAN------CINLPGWYHCECRDGYHDNGMFSP 594
Query: 631 DGTDCID 637
G C D
Sbjct: 595 SGESCED 601
Score = 87.4 bits (207), Expect = 2e-16
Identities = 73/274 (26%), Positives = 104/274 (37%), Gaps = 31/274 (11%)
Query: 385 PECCCSEGAAW--GRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRC 442
P+C A+ G+ C+ C + ICQ GR + + VCV C
Sbjct: 310 PDCPLKSALAYVDGKCCKECKS--------ICQF-QGRTYFEGERNTVYSSSGVCVLYEC 360
Query: 443 -------VNTDGSFRCECPDGYVLAPDGLSCVDA---DECALDPRICGNGTCSNTRGGYE 492
V + G +CP+ + + C D C+ N C N
Sbjct: 361 KDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHNCMENSICRNLNDRAV 420
Query: 493 CQCSPGFT--QGPDQTCVDVDECAEGRASC--TFRCHNTAGSFRCTCPYGYAVAADGVHC 548
C C GF + + C D+DECAEGR C C NT GSF C C GY + D C
Sbjct: 421 CSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGY-IRIDDYSC 479
Query: 549 RDIDECVQEPRVCPH--ACENVVGSYICKCPEGY--RRTSAPQDSENACEDINEC-EEQE 603
+ DEC+ C C N VG + C C GY T+ ++ C + C
Sbjct: 480 TEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANV 539
Query: 604 DLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C G + + + +C GF + +CI+
Sbjct: 540 CACPQGFTGPSCETDIDECSDGFVQCDSRANCIN 573
Score = 81.0 bits (191), Expect = 2e-14
Identities = 39/101 (38%), Positives = 54/101 (53%), Gaps = 8/101 (7%)
Query: 765 CVCGPGYRPAGE---VCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC 819
C C G+R E C D+DECA C + +C NT GS+ C+C+TGY + D +C
Sbjct: 421 CSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGY-IRIDDYSC 479
Query: 820 RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
+ DEC + H C + +C NT G + C C+ GY G C
Sbjct: 480 TEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTC 520
Score = 77.0 bits (181), Expect = 3e-13
Identities = 90/336 (26%), Positives = 126/336 (37%), Gaps = 53/336 (15%)
Query: 315 CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWR-FDKTAAVCVDERKELCYDEWEAGR 373
C D C E CRN N VC C G+R + A C D DE GR
Sbjct: 394 CKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCED------IDECAEGR 447
Query: 374 CH-RARPLQLARPE---CCCSEGA------AWGRYCERCPAPDSAEFMRICQGGMG---- 419
+ R + + P C C G + + E + + +C +G
Sbjct: 448 HYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNC 507
Query: 420 --RPNLTQDLDECRVR-PDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECAL 474
+P T + C+ D C GG C+ + C CP G+ G SC D DEC+
Sbjct: 508 VCKPGYTGNGTTCKAFCKDGCRNGGACIAANV---CACPQGFT----GPSCETDIDECSD 560
Query: 475 DPRICGN-GTCSNTRGGYECQCSPGFTQG-----PDQTCVDVDECAEGRASCTFR--CHN 526
C + C N G Y C+C G+ ++C D+DEC GR SC C N
Sbjct: 561 GFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFN 620
Query: 527 TAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGY---RRT 583
G + C CP+G D +H + Q + C +C C G+ RR
Sbjct: 621 LDGGYDCRCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCS------VCSCQNGFVMCRRM 674
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFL 619
D EN D+ C E + S C++ +G L
Sbjct: 675 VC--DCENPTVDLFCCPECDPRLS-SQCLHQNGETL 707
Score = 71.3 bits (167), Expect = 1e-11
Identities = 39/104 (37%), Positives = 48/104 (46%), Gaps = 12/104 (11%)
Query: 765 CVCGPGYRPAGEVC-ADVDECAVRPPPCDQL--CHNTDGSYDCLCRTGYE----LDEDGA 817
C C G+ G C D+DEC+ CD C N G Y C CR GY G
Sbjct: 540 CACPQGF--TGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGE 597
Query: 818 NCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV 859
+C D+DEC H+C IC N +G Y+C C G GD C+
Sbjct: 598 SCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGD-CI 640
Score = 65.3 bits (152), Expect = 9e-10
Identities = 32/85 (37%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Query: 776 EVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE-LDEDGANCRDVDECERDTHTCQ 833
+VC D C+ R + +C N + C CR G+ L ED A C D+DEC H C+
Sbjct: 392 KVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCR 451
Query: 834 Q--ICSNTEGSYECSCEDGYEKRGD 856
+ +C NT GS+ C C+ GY + D
Sbjct: 452 ENTMCVNTPGSFMCICKTGYIRIDD 476
Score = 61.7 bits (143), Expect = 1e-08
Identities = 42/128 (32%), Positives = 58/128 (45%), Gaps = 18/128 (14%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGY-RPAGEVCADVDECAVRPPPCDQ--LC 795
D+DECA C PG F C+C GY R C + DEC CD+ LC
Sbjct: 439 DIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALC 498
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDV--DECERDTHTC--QQICSNTEGSYECSCEDGY 851
NT G ++C+C+ GY +G C+ D C R+ C +C+ +G SCE
Sbjct: 499 FNTVGGHNCVCKPGY--TGNGTTCKAFCKDGC-RNGGACIAANVCACPQGFTGPSCETDI 555
Query: 852 EKRGDACV 859
++ D V
Sbjct: 556 DECSDGFV 563
Score = 56.8 bits (131), Expect = 3e-07
Identities = 35/103 (33%), Positives = 44/103 (42%), Gaps = 20/103 (19%)
Query: 760 PGRFRCVCGPGYR------PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYE 811
PG + C C GY P+GE C D+DEC C D +C N DG YDC C
Sbjct: 575 PGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRC----- 629
Query: 812 LDEDGANCRDVDECERD---THTCQQICSNTEGSYECSCEDGY 851
G NC +C D H Q + CSC++G+
Sbjct: 630 --PHGKNC--TGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGF 668
Score = 45.6 bits (103), Expect = 8e-04
Identities = 32/101 (31%), Positives = 35/101 (34%), Gaps = 19/101 (18%)
Query: 761 GRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYD---CLCRTGYELDEDGA 817
G CVC PGY G C C C N C C G+ G
Sbjct: 503 GGHNCVCKPGYTGNGTTCKAF---------CKDGCRNGGACIAANVCACPQGFT----GP 549
Query: 818 NCR-DVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRG 855
+C D+DEC C C N G Y C C DGY G
Sbjct: 550 SCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNG 590
>D83018-1|BAA11681.1| 816|Homo sapiens nel-related protein 2
protein.
Length = 816
Score = 149 bits (361), Expect = 4e-35
Identities = 90/257 (35%), Positives = 115/257 (44%), Gaps = 24/257 (9%)
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYE---HDNTSHLCRDVDECSWGRPPCRG 122
K D C + C + C C G+ DN C D+DEC+ GR CR
Sbjct: 396 KGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNA--YCEDIDECAEGRHYCRE 453
Query: 123 MAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GDQRICDHGD-CRNTIGSYRCECKP 180
CVN PG+F C C GY C + DEC +Q CD C NT+G + C CKP
Sbjct: 454 NTMCVNTPGSFMCICKTGYIRIDDY-SCTEHDECITNQHNCDENALCFNTVGGHNCVCKP 512
Query: 181 GYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGG 240
GYT C+ C + CRNG A +C C GF GP+ + D++EC +G
Sbjct: 513 GYTGNGTTCKAF--C---KDGCRNGGA--CIAANVCACPQGF-TGPSCE-TDIDECSDGF 563
Query: 241 MVC-RNGRCRNTVGSFRCECAPGY----TLTADGRNCRDVDECDELPHPCGRDGNPSCTN 295
+ C C N G + CEC GY + G +C D+DEC H C D C N
Sbjct: 564 VQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCAND--TICFN 621
Query: 296 TNGGYECSCGAGWKLVG 312
+GGY+C C G G
Sbjct: 622 LDGGYDCRCPHGKNCTG 638
Score = 125 bits (302), Expect = 6e-28
Identities = 88/255 (34%), Positives = 115/255 (45%), Gaps = 28/255 (10%)
Query: 106 LCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR-LTPSLDECEDVDECGDQR-IC- 162
+C+ D CS R C + C NL C C G+R L CED+DEC + R C
Sbjct: 394 VCKGYDFCS-ERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCR 452
Query: 163 DHGDCRNTIGSYRCECKPGYT-LRENVCRDVDECSRPRPVC-RNGTCENLPGAYLCHCDD 220
++ C NT GS+ C CK GY + + C + DEC + C N C N G + C C
Sbjct: 453 ENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKP 512
Query: 221 GFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECD 279
G+ G C C++G CRNG + + C C G+T G +C D+DEC
Sbjct: 513 GY-TGNGTTCKAF--CKDG---CRNGGA--CIAANVCACPQGFT----GPSCETDIDECS 560
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGW------KLVGRRCVDRDECKELPYVCAGGE- 332
+ C D +C N G Y C C G+ G C D DEC + CA
Sbjct: 561 DGFVQC--DSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTI 618
Query: 333 CRNFNGGYVCECPAG 347
C N +GGY C CP G
Sbjct: 619 CFNLDGGYDCRCPHG 633
Score = 123 bits (296), Expect = 3e-27
Identities = 76/210 (36%), Positives = 93/210 (44%), Gaps = 24/210 (11%)
Query: 425 QDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NG 482
+D+DEC C CVNT GSF C C GY+ D SC + DEC + C N
Sbjct: 439 EDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDD-YSCTEHDECITNQHNCDENA 497
Query: 483 TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR---CTCPYGY 539
C NT GG+ C C PG+T G TC +A C C N C CP G+
Sbjct: 498 LCFNTVGGHNCVCKPGYT-GNGTTC---------KAFCKDGCRNGGACIAANVCACPQGF 547
Query: 540 AVAADGVHCR-DIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENACEDI 596
G C DIDEC C C N+ G Y C+C +GY S +CEDI
Sbjct: 548 T----GPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDI 603
Query: 597 NECEEQEDLCSGG-VCINTDGSFLCDCDAG 625
+EC C+ +C N DG + C C G
Sbjct: 604 DECGTGRHSCANDTICFNLDGGYDCRCPHG 633
Score = 110 bits (265), Expect = 2e-23
Identities = 74/223 (33%), Positives = 103/223 (46%), Gaps = 25/223 (11%)
Query: 137 CPPGYRLTPS---LDECEDVDECGDQRIC-DHGDCRNTIGSYRCECKPGY-TLREN--VC 189
CP +++T S C+ D C ++ C ++ CRN C C+ G+ LRE+ C
Sbjct: 379 CPESHQITLSHSCCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYC 438
Query: 190 RDVDECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC-RNGR 247
D+DEC+ R CR T C N PG+++C C G+ + C + +EC C N
Sbjct: 439 EDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENAL 498
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
C NTVG C C PGYT +G C+ C + C G +C N C+C G
Sbjct: 499 CFNTVGGHNCVCKPGYT--GNGTTCKAF--CKD---GCRNGG--ACIAAN---VCACPQG 546
Query: 308 WKLVGRRC-VDRDECKELPYVC-AGGECRNFNGGYVCECPAGW 348
+ G C D DEC + C + C N G Y CEC G+
Sbjct: 547 F--TGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGY 587
Score = 103 bits (247), Expect = 3e-21
Identities = 69/247 (27%), Positives = 98/247 (39%), Gaps = 29/247 (11%)
Query: 402 CPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGY-VLA 460
CPA D E +I + + D C R + C N + C C DG+ L
Sbjct: 374 CPALDCPESHQITLSH-SCCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALR 432
Query: 461 PDGLSCVDADECALDPRICGNGT-CSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS 519
D C D DECA C T C NT G + C C G+ + D +C + DEC + +
Sbjct: 433 EDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHN 492
Query: 520 CTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN---VVGSYIC 574
C C NT G C C GY +G C+ C C N + + +C
Sbjct: 493 CDENALCFNTVGGHNCVCKPGYT--GNGTTCKAF---------CKDGCRNGGACIAANVC 541
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP----SE 630
CP+G+ S D + + +C+ + + CIN G + C+C G+ S
Sbjct: 542 ACPQGFTGPSCETDIDECSDGFVQCDSRAN------CINLPGWYHCECRDGYHDNGMFSP 595
Query: 631 DGTDCID 637
G C D
Sbjct: 596 SGESCED 602
Score = 87.4 bits (207), Expect = 2e-16
Identities = 73/274 (26%), Positives = 104/274 (37%), Gaps = 31/274 (11%)
Query: 385 PECCCSEGAAW--GRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRC 442
P+C A+ G+ C+ C + ICQ GR + + VCV C
Sbjct: 311 PDCPLKSALAYVDGKCCKECKS--------ICQF-QGRTYFEGERNTVYSSSGVCVLYEC 361
Query: 443 -------VNTDGSFRCECPDGYVLAPDGLSCVDA---DECALDPRICGNGTCSNTRGGYE 492
V + G +CP+ + + C D C+ N C N
Sbjct: 362 KDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHNCMENSICRNLNDRAV 421
Query: 493 CQCSPGFT--QGPDQTCVDVDECAEGRASC--TFRCHNTAGSFRCTCPYGYAVAADGVHC 548
C C GF + + C D+DECAEGR C C NT GSF C C GY + D C
Sbjct: 422 CSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGY-IRIDDYSC 480
Query: 549 RDIDECVQEPRVCPH--ACENVVGSYICKCPEGY--RRTSAPQDSENACEDINEC-EEQE 603
+ DEC+ C C N VG + C C GY T+ ++ C + C
Sbjct: 481 TEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANV 540
Query: 604 DLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C G + + + +C GF + +CI+
Sbjct: 541 CACPQGFTGPSCETDIDECSDGFVQCDSRANCIN 574
Score = 81.0 bits (191), Expect = 2e-14
Identities = 39/101 (38%), Positives = 54/101 (53%), Gaps = 8/101 (7%)
Query: 765 CVCGPGYRPAGE---VCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC 819
C C G+R E C D+DECA C + +C NT GS+ C+C+TGY + D +C
Sbjct: 422 CSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGY-IRIDDYSC 480
Query: 820 RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
+ DEC + H C + +C NT G + C C+ GY G C
Sbjct: 481 TEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTC 521
Score = 77.0 bits (181), Expect = 3e-13
Identities = 90/336 (26%), Positives = 126/336 (37%), Gaps = 53/336 (15%)
Query: 315 CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWR-FDKTAAVCVDERKELCYDEWEAGR 373
C D C E CRN N VC C G+R + A C D DE GR
Sbjct: 395 CKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCED------IDECAEGR 448
Query: 374 CH-RARPLQLARPE---CCCSEGA------AWGRYCERCPAPDSAEFMRICQGGMG---- 419
+ R + + P C C G + + E + + +C +G
Sbjct: 449 HYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNC 508
Query: 420 --RPNLTQDLDECRVR-PDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECAL 474
+P T + C+ D C GG C+ + C CP G+ G SC D DEC+
Sbjct: 509 VCKPGYTGNGTTCKAFCKDGCRNGGACIAANV---CACPQGFT----GPSCETDIDECSD 561
Query: 475 DPRICGN-GTCSNTRGGYECQCSPGFTQG-----PDQTCVDVDECAEGRASCTFR--CHN 526
C + C N G Y C+C G+ ++C D+DEC GR SC C N
Sbjct: 562 GFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFN 621
Query: 527 TAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGY---RRT 583
G + C CP+G D +H + Q + C +C C G+ RR
Sbjct: 622 LDGGYDCRCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCS------VCSCQNGFVMCRRM 675
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFL 619
D EN D+ C E + S C++ +G L
Sbjct: 676 VC--DCENPTVDLFCCPECDPRLS-SQCLHQNGETL 708
Score = 71.3 bits (167), Expect = 1e-11
Identities = 39/104 (37%), Positives = 48/104 (46%), Gaps = 12/104 (11%)
Query: 765 CVCGPGYRPAGEVC-ADVDECAVRPPPCDQL--CHNTDGSYDCLCRTGYE----LDEDGA 817
C C G+ G C D+DEC+ CD C N G Y C CR GY G
Sbjct: 541 CACPQGF--TGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGE 598
Query: 818 NCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV 859
+C D+DEC H+C IC N +G Y+C C G GD C+
Sbjct: 599 SCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGD-CI 641
Score = 65.3 bits (152), Expect = 9e-10
Identities = 32/85 (37%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Query: 776 EVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE-LDEDGANCRDVDECERDTHTCQ 833
+VC D C+ R + +C N + C CR G+ L ED A C D+DEC H C+
Sbjct: 393 KVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCR 452
Query: 834 Q--ICSNTEGSYECSCEDGYEKRGD 856
+ +C NT GS+ C C+ GY + D
Sbjct: 453 ENTMCVNTPGSFMCICKTGYIRIDD 477
Score = 61.7 bits (143), Expect = 1e-08
Identities = 42/128 (32%), Positives = 58/128 (45%), Gaps = 18/128 (14%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGY-RPAGEVCADVDECAVRPPPCDQ--LC 795
D+DECA C PG F C+C GY R C + DEC CD+ LC
Sbjct: 440 DIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALC 499
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDV--DECERDTHTC--QQICSNTEGSYECSCEDGY 851
NT G ++C+C+ GY +G C+ D C R+ C +C+ +G SCE
Sbjct: 500 FNTVGGHNCVCKPGY--TGNGTTCKAFCKDGC-RNGGACIAANVCACPQGFTGPSCETDI 556
Query: 852 EKRGDACV 859
++ D V
Sbjct: 557 DECSDGFV 564
Score = 56.8 bits (131), Expect = 3e-07
Identities = 35/103 (33%), Positives = 44/103 (42%), Gaps = 20/103 (19%)
Query: 760 PGRFRCVCGPGYR------PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYE 811
PG + C C GY P+GE C D+DEC C D +C N DG YDC C
Sbjct: 576 PGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRC----- 630
Query: 812 LDEDGANCRDVDECERD---THTCQQICSNTEGSYECSCEDGY 851
G NC +C D H Q + CSC++G+
Sbjct: 631 --PHGKNC--TGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGF 669
Score = 45.6 bits (103), Expect = 8e-04
Identities = 32/101 (31%), Positives = 35/101 (34%), Gaps = 19/101 (18%)
Query: 761 GRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYD---CLCRTGYELDEDGA 817
G CVC PGY G C C C N C C G+ G
Sbjct: 504 GGHNCVCKPGYTGNGTTCKAF---------CKDGCRNGGACIAANVCACPQGFT----GP 550
Query: 818 NCR-DVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRG 855
+C D+DEC C C N G Y C C DGY G
Sbjct: 551 SCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNG 591
>BC020544-1|AAH20544.1| 816|Homo sapiens NELL2 protein protein.
Length = 816
Score = 149 bits (361), Expect = 4e-35
Identities = 90/257 (35%), Positives = 115/257 (44%), Gaps = 24/257 (9%)
Query: 66 KPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYE---HDNTSHLCRDVDECSWGRPPCRG 122
K D C + C + C C G+ DN C D+DEC+ GR CR
Sbjct: 396 KGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNA--YCEDIDECAEGRHYCRE 453
Query: 123 MAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC-GDQRICDHGD-CRNTIGSYRCECKP 180
CVN PG+F C C GY C + DEC +Q CD C NT+G + C CKP
Sbjct: 454 NTMCVNTPGSFMCICKTGYIRIDDY-SCTEHDECITNQHNCDENALCFNTVGGHNCVCKP 512
Query: 181 GYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGG 240
GYT C+ C + CRNG A +C C GF GP+ + D++EC +G
Sbjct: 513 GYTGNGTTCKAF--C---KDGCRNGGA--CIAANVCACPQGF-TGPSCE-TDIDECSDGF 563
Query: 241 MVC-RNGRCRNTVGSFRCECAPGY----TLTADGRNCRDVDECDELPHPCGRDGNPSCTN 295
+ C C N G + CEC GY + G +C D+DEC H C D C N
Sbjct: 564 VQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCAND--TICFN 621
Query: 296 TNGGYECSCGAGWKLVG 312
+GGY+C C G G
Sbjct: 622 LDGGYDCRCPHGKNCTG 638
Score = 125 bits (302), Expect = 6e-28
Identities = 88/255 (34%), Positives = 115/255 (45%), Gaps = 28/255 (10%)
Query: 106 LCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR-LTPSLDECEDVDECGDQR-IC- 162
+C+ D CS R C + C NL C C G+R L CED+DEC + R C
Sbjct: 394 VCKGYDFCS-ERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCR 452
Query: 163 DHGDCRNTIGSYRCECKPGYT-LRENVCRDVDECSRPRPVC-RNGTCENLPGAYLCHCDD 220
++ C NT GS+ C CK GY + + C + DEC + C N C N G + C C
Sbjct: 453 ENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKP 512
Query: 221 GFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECD 279
G+ G C C++G CRNG + + C C G+T G +C D+DEC
Sbjct: 513 GY-TGNGTTCKAF--CKDG---CRNGGA--CIAANVCACPQGFT----GPSCETDIDECS 560
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGW------KLVGRRCVDRDECKELPYVCAGGE- 332
+ C D +C N G Y C C G+ G C D DEC + CA
Sbjct: 561 DGFVQC--DSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTI 618
Query: 333 CRNFNGGYVCECPAG 347
C N +GGY C CP G
Sbjct: 619 CFNLDGGYDCRCPHG 633
Score = 123 bits (296), Expect = 3e-27
Identities = 76/210 (36%), Positives = 93/210 (44%), Gaps = 24/210 (11%)
Query: 425 QDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NG 482
+D+DEC C CVNT GSF C C GY+ D SC + DEC + C N
Sbjct: 439 EDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDD-YSCTEHDECITNQHNCDENA 497
Query: 483 TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR---CTCPYGY 539
C NT GG+ C C PG+T G TC +A C C N C CP G+
Sbjct: 498 LCFNTVGGHNCVCKPGYT-GNGTTC---------KAFCKDGCRNGGACIAANVCACPQGF 547
Query: 540 AVAADGVHCR-DIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSENACEDI 596
G C DIDEC C C N+ G Y C+C +GY S +CEDI
Sbjct: 548 T----GPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDI 603
Query: 597 NECEEQEDLCSGG-VCINTDGSFLCDCDAG 625
+EC C+ +C N DG + C C G
Sbjct: 604 DECGTGRHSCANDTICFNLDGGYDCRCPHG 633
Score = 110 bits (265), Expect = 2e-23
Identities = 74/223 (33%), Positives = 103/223 (46%), Gaps = 25/223 (11%)
Query: 137 CPPGYRLTPS---LDECEDVDECGDQRIC-DHGDCRNTIGSYRCECKPGY-TLREN--VC 189
CP +++T S C+ D C ++ C ++ CRN C C+ G+ LRE+ C
Sbjct: 379 CPESHQITLSHSCCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYC 438
Query: 190 RDVDECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC-RNGR 247
D+DEC+ R CR T C N PG+++C C G+ + C + +EC C N
Sbjct: 439 EDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENAL 498
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
C NTVG C C PGYT +G C+ C + C G +C N C+C G
Sbjct: 499 CFNTVGGHNCVCKPGYT--GNGTTCKAF--CKD---GCRNGG--ACIAAN---VCACPQG 546
Query: 308 WKLVGRRC-VDRDECKELPYVC-AGGECRNFNGGYVCECPAGW 348
+ G C D DEC + C + C N G Y CEC G+
Sbjct: 547 F--TGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGY 587
Score = 103 bits (247), Expect = 3e-21
Identities = 69/247 (27%), Positives = 98/247 (39%), Gaps = 29/247 (11%)
Query: 402 CPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGY-VLA 460
CPA D E +I + + D C R + C N + C C DG+ L
Sbjct: 374 CPALDCPESHQITLSH-SCCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALR 432
Query: 461 PDGLSCVDADECALDPRICGNGT-CSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS 519
D C D DECA C T C NT G + C C G+ + D +C + DEC + +
Sbjct: 433 EDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHN 492
Query: 520 CTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN---VVGSYIC 574
C C NT G C C GY +G C+ C C N + + +C
Sbjct: 493 CDENALCFNTVGGHNCVCKPGYT--GNGTTCKAF---------CKDGCRNGGACIAANVC 541
Query: 575 KCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP----SE 630
CP+G+ S D + + +C+ + + CIN G + C+C G+ S
Sbjct: 542 ACPQGFTGPSCETDIDECSDGFVQCDSRAN------CINLPGWYHCECRDGYHDNGMFSP 595
Query: 631 DGTDCID 637
G C D
Sbjct: 596 SGESCED 602
Score = 87.4 bits (207), Expect = 2e-16
Identities = 73/274 (26%), Positives = 104/274 (37%), Gaps = 31/274 (11%)
Query: 385 PECCCSEGAAW--GRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRC 442
P+C A+ G+ C+ C + ICQ GR + + VCV C
Sbjct: 311 PDCPLKSALAYVDGKCCKECKS--------ICQF-QGRTYFEGERNTVYSSSGVCVLYEC 361
Query: 443 -------VNTDGSFRCECPDGYVLAPDGLSCVDA---DECALDPRICGNGTCSNTRGGYE 492
V + G +CP+ + + C D C+ N C N
Sbjct: 362 KDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHNCMENSICRNLNDRAV 421
Query: 493 CQCSPGFT--QGPDQTCVDVDECAEGRASC--TFRCHNTAGSFRCTCPYGYAVAADGVHC 548
C C GF + + C D+DECAEGR C C NT GSF C C GY + D C
Sbjct: 422 CSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGY-IRIDDYSC 480
Query: 549 RDIDECVQEPRVCPH--ACENVVGSYICKCPEGY--RRTSAPQDSENACEDINEC-EEQE 603
+ DEC+ C C N VG + C C GY T+ ++ C + C
Sbjct: 481 TEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANV 540
Query: 604 DLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
C G + + + +C GF + +CI+
Sbjct: 541 CACPQGFTGPSCETDIDECSDGFVQCDSRANCIN 574
Score = 81.0 bits (191), Expect = 2e-14
Identities = 39/101 (38%), Positives = 54/101 (53%), Gaps = 8/101 (7%)
Query: 765 CVCGPGYRPAGE---VCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC 819
C C G+R E C D+DECA C + +C NT GS+ C+C+TGY + D +C
Sbjct: 422 CSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGY-IRIDDYSC 480
Query: 820 RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
+ DEC + H C + +C NT G + C C+ GY G C
Sbjct: 481 TEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTC 521
Score = 77.0 bits (181), Expect = 3e-13
Identities = 90/336 (26%), Positives = 126/336 (37%), Gaps = 53/336 (15%)
Query: 315 CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWR-FDKTAAVCVDERKELCYDEWEAGR 373
C D C E CRN N VC C G+R + A C D DE GR
Sbjct: 395 CKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCED------IDECAEGR 448
Query: 374 CH-RARPLQLARPE---CCCSEGA------AWGRYCERCPAPDSAEFMRICQGGMG---- 419
+ R + + P C C G + + E + + +C +G
Sbjct: 449 HYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNC 508
Query: 420 --RPNLTQDLDECRVR-PDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECAL 474
+P T + C+ D C GG C+ + C CP G+ G SC D DEC+
Sbjct: 509 VCKPGYTGNGTTCKAFCKDGCRNGGACIAANV---CACPQGFT----GPSCETDIDECSD 561
Query: 475 DPRICGN-GTCSNTRGGYECQCSPGFTQG-----PDQTCVDVDECAEGRASCTFR--CHN 526
C + C N G Y C+C G+ ++C D+DEC GR SC C N
Sbjct: 562 GFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFN 621
Query: 527 TAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGY---RRT 583
G + C CP+G D +H + Q + C +C C G+ RR
Sbjct: 622 LDGGYDCRCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCS------VCSCQNGFVMCRRM 675
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINTDGSFL 619
D EN D+ C E + S C++ +G L
Sbjct: 676 VC--DCENPTVDLFCCPECDPRLS-SQCLHQNGETL 708
Score = 71.3 bits (167), Expect = 1e-11
Identities = 39/104 (37%), Positives = 48/104 (46%), Gaps = 12/104 (11%)
Query: 765 CVCGPGYRPAGEVC-ADVDECAVRPPPCDQL--CHNTDGSYDCLCRTGYE----LDEDGA 817
C C G+ G C D+DEC+ CD C N G Y C CR GY G
Sbjct: 541 CACPQGF--TGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGE 598
Query: 818 NCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV 859
+C D+DEC H+C IC N +G Y+C C G GD C+
Sbjct: 599 SCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGD-CI 641
Score = 65.3 bits (152), Expect = 9e-10
Identities = 32/85 (37%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Query: 776 EVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE-LDEDGANCRDVDECERDTHTCQ 833
+VC D C+ R + +C N + C CR G+ L ED A C D+DEC H C+
Sbjct: 393 KVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCR 452
Query: 834 Q--ICSNTEGSYECSCEDGYEKRGD 856
+ +C NT GS+ C C+ GY + D
Sbjct: 453 ENTMCVNTPGSFMCICKTGYIRIDD 477
Score = 61.7 bits (143), Expect = 1e-08
Identities = 42/128 (32%), Positives = 58/128 (45%), Gaps = 18/128 (14%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGY-RPAGEVCADVDECAVRPPPCDQ--LC 795
D+DECA C PG F C+C GY R C + DEC CD+ LC
Sbjct: 440 DIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALC 499
Query: 796 HNTDGSYDCLCRTGYELDEDGANCRDV--DECERDTHTC--QQICSNTEGSYECSCEDGY 851
NT G ++C+C+ GY +G C+ D C R+ C +C+ +G SCE
Sbjct: 500 FNTVGGHNCVCKPGY--TGNGTTCKAFCKDGC-RNGGACIAANVCACPQGFTGPSCETDI 556
Query: 852 EKRGDACV 859
++ D V
Sbjct: 557 DECSDGFV 564
Score = 56.8 bits (131), Expect = 3e-07
Identities = 35/103 (33%), Positives = 44/103 (42%), Gaps = 20/103 (19%)
Query: 760 PGRFRCVCGPGYR------PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYE 811
PG + C C GY P+GE C D+DEC C D +C N DG YDC C
Sbjct: 576 PGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRC----- 630
Query: 812 LDEDGANCRDVDECERD---THTCQQICSNTEGSYECSCEDGY 851
G NC +C D H Q + CSC++G+
Sbjct: 631 --PHGKNC--TGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGF 669
Score = 45.6 bits (103), Expect = 8e-04
Identities = 32/101 (31%), Positives = 35/101 (34%), Gaps = 19/101 (18%)
Query: 761 GRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYD---CLCRTGYELDEDGA 817
G CVC PGY G C C C N C C G+ G
Sbjct: 504 GGHNCVCKPGYTGNGTTCKAF---------CKDGCRNGGACIAANVCACPQGFT----GP 550
Query: 818 NCR-DVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRG 855
+C D+DEC C C N G Y C C DGY G
Sbjct: 551 SCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNG 591
>D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein.
Length = 810
Score = 147 bits (355), Expect = 2e-34
Identities = 89/246 (36%), Positives = 114/246 (46%), Gaps = 22/246 (8%)
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGCDHGY-EHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
C P+ + C + T C C GY S C D+DEC+ C CVNL
Sbjct: 395 CAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNL 454
Query: 130 PGAFECRCPPGYRLTPSLDECEDVDECGD-QRICD-HGDCRNTIGSYRCECKPGYTLREN 187
PG + C C PGY C + DECG Q CD + C NT+ + C CKPGY
Sbjct: 455 PGLYRCDCVPGYIRVDDF-SCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGT 513
Query: 188 VCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN- 245
+CR E CR GTC P C C GF G + + D++EC EG + C N
Sbjct: 514 ICRAFCE-----EGCRYGGTCV-APNK--CVCPSGF-TGSHCE-KDIDECSEGIIECHNH 563
Query: 246 GRCRNTVGSFRCECAPGY----TLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
RC N G + CEC G+ T + G +C D+DEC H C D +C N GG++
Sbjct: 564 SRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDS--ACINLAGGFD 621
Query: 302 CSCGAG 307
C C +G
Sbjct: 622 CLCPSG 627
Score = 120 bits (289), Expect = 2e-26
Identities = 77/217 (35%), Positives = 102/217 (47%), Gaps = 21/217 (9%)
Query: 425 QDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NG 482
+D+DEC + C CVN G +RC+C GY+ D SC + DEC C N
Sbjct: 433 EDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDD-FSCTEHDECGSGQHNCDENA 491
Query: 483 TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVA 542
C+NT G+ C C PG+ G C C EG C + A + +C CP G+
Sbjct: 492 ICTNTVQGHSCTCKPGYV-GNGTICRAF--CEEG---CRYGGTCVAPN-KCVCPSGFT-- 542
Query: 543 ADGVHC-RDIDECVQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENACEDINEC 599
G HC +DIDEC + C + C N+ G Y C+C G+ S +C DI+EC
Sbjct: 543 --GSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDEC 600
Query: 600 EEQEDLC-SGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
+ C + CIN G F C C +G PS G DC
Sbjct: 601 ALRTHTCWNDSACINLAGGFDCLCPSG--PSCSG-DC 634
Score = 111 bits (268), Expect = 8e-24
Identities = 89/295 (30%), Positives = 116/295 (39%), Gaps = 52/295 (17%)
Query: 217 HCDDGFKAGPNNDCVDV----NECREGGMVCRNGRCRNTVGSFRCECAPGY-TLTADGRN 271
+C + P N C V N C EG N C+N CEC GY ++ D
Sbjct: 372 NCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAY 431
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW-KLVGRRCVDRDECKELPYVC-A 329
C D+DEC H C N C N G Y C C G+ ++ C + DEC + C
Sbjct: 432 CEDIDECAAKMHYC--HANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDE 489
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C N G+ C C G+ + T +C +E C G C +A +C C
Sbjct: 490 NAICTNTVQGHSCTCKPGYVGNGT--ICRAFCEEGCR---YGGTC-------VAPNKCVC 537
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGS 448
G G +CE+ D+DEC C RCVN G
Sbjct: 538 PSGFT-GSHCEK------------------------DIDECSEGIIECHNHSRCVNLPGW 572
Query: 449 FRCECPDGY----VLAPDGLSCVDADECALDPRICGN-GTCSNTRGGYECQCSPG 498
+ CEC G+ + G SC+D DECAL C N C N GG++C C G
Sbjct: 573 YHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 110 bits (264), Expect = 2e-23
Identities = 92/342 (26%), Positives = 126/342 (36%), Gaps = 33/342 (9%)
Query: 316 VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCH 375
VD D C+ ECR + C P D + ++C + G
Sbjct: 287 VDGDHCRNCTCKSGAVECRRMS----CP-PLNCSPDSLPVHIAGQCCKVCRPKCIYGGKV 341
Query: 376 RARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPD 435
A ++ C G + E CP + +E I + + + C P
Sbjct: 342 LAEGQRILTKSCRECRGGVLVKITEMCPPLNCSEKDHILPENQCC-RVCRGHNFCAEGPK 400
Query: 436 VCVGGRCVNTDGSFRCECPDGYV-LAPDGLSCVDADECALDPRIC-GNGTCSNTRGGYEC 493
C N + CEC GY+ + D C D DECA C N C N G Y C
Sbjct: 401 CGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRC 460
Query: 494 QCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDI 551
C PG+ + D +C + DEC G+ +C C NT CTC GY +G CR
Sbjct: 461 DCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY--VGNGTICRAF 518
Query: 552 DECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVC 611
E C + V C CP G+ + +D + E I EC C
Sbjct: 519 CE-----EGCRYG-GTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSR------C 566
Query: 612 INTDGSFLCDCDAGFEP----SEDGTDCID-----RRTGTCY 644
+N G + C+C +GF S G CID RT TC+
Sbjct: 567 VNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCW 608
Score = 100 bits (239), Expect = 3e-20
Identities = 82/261 (31%), Positives = 109/261 (41%), Gaps = 28/261 (10%)
Query: 24 CCSV--GHAWGAPCEACPPRGSPAH---TALCGEKPGEYINPVTNET--KPIDECDIMPQ 76
CC V GH + A C + A C K G YI+ + + IDEC
Sbjct: 385 CCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSG-YISVQGDSAYCEDIDECAAKMH 443
Query: 77 LCKPGT-CHDTPTGFQCGCDHGYEH-DNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFE 134
C T C + P ++C C GY D+ S C + DEC G+ C A C N
Sbjct: 444 YCHANTVCVNLPGLYRCDCVPGYIRVDDFS--CTEHDECGSGQHNCDENAICTNTVQGHS 501
Query: 135 CRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDE 194
C C PGY ++ C E G C +G + +C C G+T + +D+DE
Sbjct: 502 CTCKPGYVGNGTI--CRAFCEEG----CRYGG--TCVAPNKCVCPSGFT-GSHCEKDIDE 552
Query: 195 CSRPRPVCRNGT-CENLPGAYLCHC-----DDGFKAGPNNDCVDVNECREGGMVCRN-GR 247
CS C N + C NLPG Y C C DDG + C+D++EC C N
Sbjct: 553 CSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSA 612
Query: 248 CRNTVGSFRCECAPGYTLTAD 268
C N G F C C G + + D
Sbjct: 613 CINLAGGFDCLCPSGPSCSGD 633
Score = 97.5 bits (232), Expect = 2e-19
Identities = 85/277 (30%), Positives = 115/277 (41%), Gaps = 45/277 (16%)
Query: 188 VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA--GPNNDCVDVNECREGGMVCR- 244
VCR + C+ N C+N C C G+ + G + C D++EC C
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHA 447
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
N C N G +RC+C PGY + D +C + DEC H C D N CTNT G+ C+C
Sbjct: 448 NTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNC--DENAICTNTVQGHSCTC 504
Query: 305 GAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
G+ VG + R C+E C GG C N C CP+G+ T + C K+
Sbjct: 505 KPGY--VGNGTICRAFCEE---GCRYGGTCVAPN---KCVCPSGF----TGSHC---EKD 549
Query: 364 LCYDEWEAG--RCHRARPLQLARPECCCSEGAAWGRYCE-RCPAPDSAEFMRICQGGMGR 420
+ DE G CH C W +CE R D + + +
Sbjct: 550 I--DECSEGIIECHN---------HSRCVNLPGW-YHCECRSGFHDDGTYSLSGESCI-- 595
Query: 421 PNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDG 456
D+DEC +R C C+N G F C CP G
Sbjct: 596 -----DIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 77.8 bits (183), Expect = 2e-13
Identities = 89/332 (26%), Positives = 131/332 (39%), Gaps = 47/332 (14%)
Query: 313 RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGW-RFDKTAAVC--VDE--------- 360
R C + C E P EC+N+N CEC +G+ +A C +DE
Sbjct: 387 RVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCH 446
Query: 361 RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMG- 419
+C + RC P + + C+E G C ++A QG
Sbjct: 447 ANTVCVNLPGLYRCDCV-PGYIRVDDFSCTEHDECGSGQHNCD--ENAICTNTVQGHSCT 503
Query: 420 -RPNLTQDLDECRVR-PDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCV-DADECALD 475
+P + CR + C GG CV + +C CP G+ G C D DEC+
Sbjct: 504 CKPGYVGNGTICRAFCEEGCRYGGTCVAPN---KCVCPSGFT----GSHCEKDIDECSEG 556
Query: 476 PRICGNGT-CSNTRGGYECQCSPGFTQG-----PDQTCVDVDECAEGRASC--TFRCHNT 527
C N + C N G Y C+C GF ++C+D+DECA +C C N
Sbjct: 557 IIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINL 616
Query: 528 AGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEG---YRRTS 584
AG F C CP G + + D H + Q + C +C C +G RRT+
Sbjct: 617 AGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCS------VCSCKDGKIFCRRTA 670
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDG 616
D +N D+ C E + + C++ +G
Sbjct: 671 C--DCQNPSADLFCCPECDTRVT-SQCLDQNG 699
Score = 70.1 bits (164), Expect = 3e-11
Identities = 36/101 (35%), Positives = 49/101 (48%), Gaps = 8/101 (7%)
Query: 765 CVCGPGY---RPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANC 819
C C GY + C D+DECA + C + +C N G Y C C GY + D +C
Sbjct: 416 CECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY-IRVDDFSC 474
Query: 820 RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
+ DEC H C + IC+NT + C+C+ GY G C
Sbjct: 475 TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTIC 515
Score = 68.1 bits (159), Expect = 1e-10
Identities = 42/111 (37%), Positives = 52/111 (46%), Gaps = 14/111 (12%)
Query: 756 GLC-APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYE 811
G C AP + CVC G+ G C D+DEC+ C C N G Y C CR+G+
Sbjct: 527 GTCVAPNK--CVCPSGF--TGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFH 582
Query: 812 LDE----DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGD 856
D G +C D+DEC THTC C N G ++C C G GD
Sbjct: 583 DDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGD 633
Score = 52.8 bits (121), Expect = 5e-06
Identities = 34/99 (34%), Positives = 43/99 (43%), Gaps = 14/99 (14%)
Query: 760 PGRFRCVCGPG------YRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYE 811
PG + C C G Y +GE C D+DECA+R C D C N G +DCLC +G
Sbjct: 570 PGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPS 629
Query: 812 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
D C + H Q + CSC+DG
Sbjct: 630 CSGD---CPHEGGLK---HNGQVWTLKEDRCSVCSCKDG 662
Score = 52.0 bits (119), Expect = 9e-06
Identities = 32/85 (37%), Positives = 40/85 (47%), Gaps = 13/85 (15%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGY-RPAGEVCADVDECAVRPPPCDQ--LC 795
D+DECAA C PG +RC C PGY R C + DEC CD+ +C
Sbjct: 434 DIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAIC 493
Query: 796 HNTDGSYDCLCRTGYELDEDGANCR 820
NT + C C+ GY +G CR
Sbjct: 494 TNTVQGHSCTCKPGYV--GNGTICR 516
Score = 42.3 bits (95), Expect = 0.007
Identities = 28/94 (29%), Positives = 38/94 (40%), Gaps = 13/94 (13%)
Query: 765 CVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDVD 823
C C PGY G +C E R C + C+C +G+ G++C +D+D
Sbjct: 502 CTCKPGYVGNGTICRAFCEEGCR---YGGTCVAPN---KCVCPSGFT----GSHCEKDID 551
Query: 824 ECERDTHTCQQI--CSNTEGSYECSCEDGYEKRG 855
EC C C N G Y C C G+ G
Sbjct: 552 ECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDG 585
>BC096102-1|AAH96102.1| 810|Homo sapiens NEL-like 1 (chicken)
protein.
Length = 810
Score = 147 bits (355), Expect = 2e-34
Identities = 89/246 (36%), Positives = 114/246 (46%), Gaps = 22/246 (8%)
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGCDHGY-EHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
C P+ + C + T C C GY S C D+DEC+ C CVNL
Sbjct: 395 CAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNL 454
Query: 130 PGAFECRCPPGYRLTPSLDECEDVDECGD-QRICD-HGDCRNTIGSYRCECKPGYTLREN 187
PG + C C PGY C + DECG Q CD + C NT+ + C CKPGY
Sbjct: 455 PGLYRCDCVPGYIRVDDF-SCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGT 513
Query: 188 VCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN- 245
+CR E CR GTC P C C GF G + + D++EC EG + C N
Sbjct: 514 ICRAFCE-----EGCRYGGTCV-APNK--CVCPSGF-TGSHCE-KDIDECSEGIIECHNH 563
Query: 246 GRCRNTVGSFRCECAPGY----TLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
RC N G + CEC G+ T + G +C D+DEC H C D +C N GG++
Sbjct: 564 SRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDS--ACINLAGGFD 621
Query: 302 CSCGAG 307
C C +G
Sbjct: 622 CLCPSG 627
Score = 120 bits (289), Expect = 2e-26
Identities = 77/217 (35%), Positives = 102/217 (47%), Gaps = 21/217 (9%)
Query: 425 QDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NG 482
+D+DEC + C CVN G +RC+C GY+ D SC + DEC C N
Sbjct: 433 EDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDD-FSCTEHDECGSGQHNCDENA 491
Query: 483 TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVA 542
C+NT G+ C C PG+ G C C EG C + A + +C CP G+
Sbjct: 492 ICTNTVQGHSCTCKPGYV-GNGTICRAF--CEEG---CRYGGTCVAPN-KCVCPSGFT-- 542
Query: 543 ADGVHC-RDIDECVQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENACEDINEC 599
G HC +DIDEC + C + C N+ G Y C+C G+ S +C DI+EC
Sbjct: 543 --GSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDEC 600
Query: 600 EEQEDLC-SGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
+ C + CIN G F C C +G PS G DC
Sbjct: 601 ALRTHTCWNDSACINLAGGFDCLCPSG--PSCSG-DC 634
Score = 111 bits (268), Expect = 8e-24
Identities = 89/295 (30%), Positives = 116/295 (39%), Gaps = 52/295 (17%)
Query: 217 HCDDGFKAGPNNDCVDV----NECREGGMVCRNGRCRNTVGSFRCECAPGY-TLTADGRN 271
+C + P N C V N C EG N C+N CEC GY ++ D
Sbjct: 372 NCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAY 431
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW-KLVGRRCVDRDECKELPYVC-A 329
C D+DEC H C N C N G Y C C G+ ++ C + DEC + C
Sbjct: 432 CEDIDECAAKMHYC--HANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDE 489
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C N G+ C C G+ + T +C +E C G C +A +C C
Sbjct: 490 NAICTNTVQGHSCTCKPGYVGNGT--ICRAFCEEGCR---YGGTC-------VAPNKCVC 537
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGS 448
G G +CE+ D+DEC C RCVN G
Sbjct: 538 PSGFT-GSHCEK------------------------DIDECSEGIIECHNHSRCVNLPGW 572
Query: 449 FRCECPDGY----VLAPDGLSCVDADECALDPRICGN-GTCSNTRGGYECQCSPG 498
+ CEC G+ + G SC+D DECAL C N C N GG++C C G
Sbjct: 573 YHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 110 bits (264), Expect = 2e-23
Identities = 92/342 (26%), Positives = 126/342 (36%), Gaps = 33/342 (9%)
Query: 316 VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCH 375
VD D C+ ECR + C P D + ++C + G
Sbjct: 287 VDGDHCRNCTCKSGAVECRRMS----CP-PLNCSPDSLPVHIAGQCCKVCRPKCIYGGKV 341
Query: 376 RARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPD 435
A ++ C G + E CP + +E I + + + C P
Sbjct: 342 LAEGQRILTKSCRECRGGVLVKITEMCPPLNCSEKDHILPENQCC-RVCRGHNFCAEGPK 400
Query: 436 VCVGGRCVNTDGSFRCECPDGYV-LAPDGLSCVDADECALDPRIC-GNGTCSNTRGGYEC 493
C N + CEC GY+ + D C D DECA C N C N G Y C
Sbjct: 401 CGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRC 460
Query: 494 QCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDI 551
C PG+ + D +C + DEC G+ +C C NT CTC GY +G CR
Sbjct: 461 DCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY--VGNGTICRAF 518
Query: 552 DECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVC 611
E C + V C CP G+ + +D + E I EC C
Sbjct: 519 CE-----EGCRYG-GTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSR------C 566
Query: 612 INTDGSFLCDCDAGFEP----SEDGTDCID-----RRTGTCY 644
+N G + C+C +GF S G CID RT TC+
Sbjct: 567 VNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCW 608
Score = 100 bits (239), Expect = 3e-20
Identities = 82/261 (31%), Positives = 109/261 (41%), Gaps = 28/261 (10%)
Query: 24 CCSV--GHAWGAPCEACPPRGSPAH---TALCGEKPGEYINPVTNET--KPIDECDIMPQ 76
CC V GH + A C + A C K G YI+ + + IDEC
Sbjct: 385 CCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSG-YISVQGDSAYCEDIDECAAKMH 443
Query: 77 LCKPGT-CHDTPTGFQCGCDHGYEH-DNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFE 134
C T C + P ++C C GY D+ S C + DEC G+ C A C N
Sbjct: 444 YCHANTVCVNLPGLYRCDCVPGYIRVDDFS--CTEHDECGSGQHNCDENAICTNTVQGHS 501
Query: 135 CRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDE 194
C C PGY ++ C E G C +G + +C C G+T + +D+DE
Sbjct: 502 CTCKPGYVGNGTI--CRAFCEEG----CRYGG--TCVAPNKCVCPSGFT-GSHCEKDIDE 552
Query: 195 CSRPRPVCRNGT-CENLPGAYLCHC-----DDGFKAGPNNDCVDVNECREGGMVCRN-GR 247
CS C N + C NLPG Y C C DDG + C+D++EC C N
Sbjct: 553 CSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSA 612
Query: 248 CRNTVGSFRCECAPGYTLTAD 268
C N G F C C G + + D
Sbjct: 613 CINLAGGFDCLCPSGPSCSGD 633
Score = 97.5 bits (232), Expect = 2e-19
Identities = 85/277 (30%), Positives = 115/277 (41%), Gaps = 45/277 (16%)
Query: 188 VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA--GPNNDCVDVNECREGGMVCR- 244
VCR + C+ N C+N C C G+ + G + C D++EC C
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHA 447
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
N C N G +RC+C PGY + D +C + DEC H C D N CTNT G+ C+C
Sbjct: 448 NTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNC--DENAICTNTVQGHSCTC 504
Query: 305 GAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
G+ VG + R C+E C GG C N C CP+G+ T + C K+
Sbjct: 505 KPGY--VGNGTICRAFCEE---GCRYGGTCVAPN---KCVCPSGF----TGSHC---EKD 549
Query: 364 LCYDEWEAG--RCHRARPLQLARPECCCSEGAAWGRYCE-RCPAPDSAEFMRICQGGMGR 420
+ DE G CH C W +CE R D + + +
Sbjct: 550 I--DECSEGIIECHN---------HSRCVNLPGW-YHCECRSGFHDDGTYSLSGESCI-- 595
Query: 421 PNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDG 456
D+DEC +R C C+N G F C CP G
Sbjct: 596 -----DIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 77.8 bits (183), Expect = 2e-13
Identities = 89/332 (26%), Positives = 131/332 (39%), Gaps = 47/332 (14%)
Query: 313 RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGW-RFDKTAAVC--VDE--------- 360
R C + C E P EC+N+N CEC +G+ +A C +DE
Sbjct: 387 RVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCH 446
Query: 361 RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMG- 419
+C + RC P + + C+E G C ++A QG
Sbjct: 447 ANTVCVNLPGLYRCDCV-PGYIRVDDFSCTEHDECGSGQHNCD--ENAICTNTVQGHSCT 503
Query: 420 -RPNLTQDLDECRVR-PDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCV-DADECALD 475
+P + CR + C GG CV + +C CP G+ G C D DEC+
Sbjct: 504 CKPGYVGNGTICRAFCEEGCRYGGTCVAPN---KCVCPSGFT----GSHCEKDIDECSEG 556
Query: 476 PRICGNGT-CSNTRGGYECQCSPGFTQG-----PDQTCVDVDECAEGRASC--TFRCHNT 527
C N + C N G Y C+C GF ++C+D+DECA +C C N
Sbjct: 557 IIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINL 616
Query: 528 AGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEG---YRRTS 584
AG F C CP G + + D H + Q + C +C C +G RRT+
Sbjct: 617 AGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCS------VCSCKDGKIFCRRTA 670
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDG 616
D +N D+ C E + + C++ +G
Sbjct: 671 C--DCQNPSADLFCCPECDTRVT-SQCLDQNG 699
Score = 70.1 bits (164), Expect = 3e-11
Identities = 36/101 (35%), Positives = 49/101 (48%), Gaps = 8/101 (7%)
Query: 765 CVCGPGY---RPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANC 819
C C GY + C D+DECA + C + +C N G Y C C GY + D +C
Sbjct: 416 CECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY-IRVDDFSC 474
Query: 820 RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
+ DEC H C + IC+NT + C+C+ GY G C
Sbjct: 475 TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTIC 515
Score = 68.1 bits (159), Expect = 1e-10
Identities = 42/111 (37%), Positives = 52/111 (46%), Gaps = 14/111 (12%)
Query: 756 GLC-APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYE 811
G C AP + CVC G+ G C D+DEC+ C C N G Y C CR+G+
Sbjct: 527 GTCVAPNK--CVCPSGF--TGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFH 582
Query: 812 LDE----DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGD 856
D G +C D+DEC THTC C N G ++C C G GD
Sbjct: 583 DDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGD 633
Score = 52.8 bits (121), Expect = 5e-06
Identities = 34/99 (34%), Positives = 43/99 (43%), Gaps = 14/99 (14%)
Query: 760 PGRFRCVCGPG------YRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYE 811
PG + C C G Y +GE C D+DECA+R C D C N G +DCLC +G
Sbjct: 570 PGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPS 629
Query: 812 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
D C + H Q + CSC+DG
Sbjct: 630 CSGD---CPHEGGLK---HNGQVWTLKEDRCSVCSCKDG 662
Score = 52.0 bits (119), Expect = 9e-06
Identities = 32/85 (37%), Positives = 40/85 (47%), Gaps = 13/85 (15%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGY-RPAGEVCADVDECAVRPPPCDQ--LC 795
D+DECAA C PG +RC C PGY R C + DEC CD+ +C
Sbjct: 434 DIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAIC 493
Query: 796 HNTDGSYDCLCRTGYELDEDGANCR 820
NT + C C+ GY +G CR
Sbjct: 494 TNTVQGHSCTCKPGYV--GNGTICR 516
Score = 42.3 bits (95), Expect = 0.007
Identities = 28/94 (29%), Positives = 38/94 (40%), Gaps = 13/94 (13%)
Query: 765 CVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDVD 823
C C PGY G +C E R C + C+C +G+ G++C +D+D
Sbjct: 502 CTCKPGYVGNGTICRAFCEEGCR---YGGTCVAPN---KCVCPSGFT----GSHCEKDID 551
Query: 824 ECERDTHTCQQI--CSNTEGSYECSCEDGYEKRG 855
EC C C N G Y C C G+ G
Sbjct: 552 ECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDG 585
>BC096101-1|AAH96101.1| 810|Homo sapiens NEL-like 1 (chicken)
protein.
Length = 810
Score = 147 bits (355), Expect = 2e-34
Identities = 89/246 (36%), Positives = 114/246 (46%), Gaps = 22/246 (8%)
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGCDHGY-EHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
C P+ + C + T C C GY S C D+DEC+ C CVNL
Sbjct: 395 CAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNL 454
Query: 130 PGAFECRCPPGYRLTPSLDECEDVDECGD-QRICD-HGDCRNTIGSYRCECKPGYTLREN 187
PG + C C PGY C + DECG Q CD + C NT+ + C CKPGY
Sbjct: 455 PGLYRCDCVPGYIRVDDF-SCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGT 513
Query: 188 VCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN- 245
+CR E CR GTC P C C GF G + + D++EC EG + C N
Sbjct: 514 ICRAFCE-----EGCRYGGTCV-APNK--CVCPSGF-TGSHCE-KDIDECSEGIIECHNH 563
Query: 246 GRCRNTVGSFRCECAPGY----TLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
RC N G + CEC G+ T + G +C D+DEC H C D +C N GG++
Sbjct: 564 SRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDS--ACINLAGGFD 621
Query: 302 CSCGAG 307
C C +G
Sbjct: 622 CLCPSG 627
Score = 120 bits (289), Expect = 2e-26
Identities = 77/217 (35%), Positives = 102/217 (47%), Gaps = 21/217 (9%)
Query: 425 QDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NG 482
+D+DEC + C CVN G +RC+C GY+ D SC + DEC C N
Sbjct: 433 EDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDD-FSCTEHDECGSGQHNCDENA 491
Query: 483 TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVA 542
C+NT G+ C C PG+ G C C EG C + A + +C CP G+
Sbjct: 492 ICTNTVQGHSCTCKPGYV-GNGTICRAF--CEEG---CRYGGTCVAPN-KCVCPSGFT-- 542
Query: 543 ADGVHC-RDIDECVQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENACEDINEC 599
G HC +DIDEC + C + C N+ G Y C+C G+ S +C DI+EC
Sbjct: 543 --GSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDEC 600
Query: 600 EEQEDLC-SGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
+ C + CIN G F C C +G PS G DC
Sbjct: 601 ALRTHTCWNDSACINLAGGFDCLCPSG--PSCSG-DC 634
Score = 111 bits (268), Expect = 8e-24
Identities = 89/295 (30%), Positives = 116/295 (39%), Gaps = 52/295 (17%)
Query: 217 HCDDGFKAGPNNDCVDV----NECREGGMVCRNGRCRNTVGSFRCECAPGY-TLTADGRN 271
+C + P N C V N C EG N C+N CEC GY ++ D
Sbjct: 372 NCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAY 431
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW-KLVGRRCVDRDECKELPYVC-A 329
C D+DEC H C N C N G Y C C G+ ++ C + DEC + C
Sbjct: 432 CEDIDECAAKMHYC--HANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDE 489
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C N G+ C C G+ + T +C +E C G C +A +C C
Sbjct: 490 NAICTNTVQGHSCTCKPGYVGNGT--ICRAFCEEGCR---YGGTC-------VAPNKCVC 537
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGS 448
G G +CE+ D+DEC C RCVN G
Sbjct: 538 PSGFT-GSHCEK------------------------DIDECSEGIIECHNHSRCVNLPGW 572
Query: 449 FRCECPDGY----VLAPDGLSCVDADECALDPRICGN-GTCSNTRGGYECQCSPG 498
+ CEC G+ + G SC+D DECAL C N C N GG++C C G
Sbjct: 573 YHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 110 bits (264), Expect = 2e-23
Identities = 92/342 (26%), Positives = 126/342 (36%), Gaps = 33/342 (9%)
Query: 316 VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCH 375
VD D C+ ECR + C P D + ++C + G
Sbjct: 287 VDGDHCRNCTCKSGAVECRRMS----CP-PLNCSPDSLPVHIAGQCCKVCRPKCIYGGKV 341
Query: 376 RARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPD 435
A ++ C G + E CP + +E I + + + C P
Sbjct: 342 LAEGQRILTKSCRECRGGVLVKITEMCPPLNCSEKDHILPENQCC-RVCRGHNFCAEGPK 400
Query: 436 VCVGGRCVNTDGSFRCECPDGYV-LAPDGLSCVDADECALDPRIC-GNGTCSNTRGGYEC 493
C N + CEC GY+ + D C D DECA C N C N G Y C
Sbjct: 401 CGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRC 460
Query: 494 QCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDI 551
C PG+ + D +C + DEC G+ +C C NT CTC GY +G CR
Sbjct: 461 DCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY--VGNGTICRAF 518
Query: 552 DECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVC 611
E C + V C CP G+ + +D + E I EC C
Sbjct: 519 CE-----EGCRYG-GTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSR------C 566
Query: 612 INTDGSFLCDCDAGFEP----SEDGTDCID-----RRTGTCY 644
+N G + C+C +GF S G CID RT TC+
Sbjct: 567 VNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCW 608
Score = 100 bits (239), Expect = 3e-20
Identities = 82/261 (31%), Positives = 109/261 (41%), Gaps = 28/261 (10%)
Query: 24 CCSV--GHAWGAPCEACPPRGSPAH---TALCGEKPGEYINPVTNET--KPIDECDIMPQ 76
CC V GH + A C + A C K G YI+ + + IDEC
Sbjct: 385 CCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSG-YISVQGDSAYCEDIDECAAKMH 443
Query: 77 LCKPGT-CHDTPTGFQCGCDHGYEH-DNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFE 134
C T C + P ++C C GY D+ S C + DEC G+ C A C N
Sbjct: 444 YCHANTVCVNLPGLYRCDCVPGYIRVDDFS--CTEHDECGSGQHNCDENAICTNTVQGHS 501
Query: 135 CRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDE 194
C C PGY ++ C E G C +G + +C C G+T + +D+DE
Sbjct: 502 CTCKPGYVGNGTI--CRAFCEEG----CRYGG--TCVAPNKCVCPSGFT-GSHCEKDIDE 552
Query: 195 CSRPRPVCRNGT-CENLPGAYLCHC-----DDGFKAGPNNDCVDVNECREGGMVCRN-GR 247
CS C N + C NLPG Y C C DDG + C+D++EC C N
Sbjct: 553 CSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSA 612
Query: 248 CRNTVGSFRCECAPGYTLTAD 268
C N G F C C G + + D
Sbjct: 613 CINLAGGFDCLCPSGPSCSGD 633
Score = 97.5 bits (232), Expect = 2e-19
Identities = 85/277 (30%), Positives = 115/277 (41%), Gaps = 45/277 (16%)
Query: 188 VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA--GPNNDCVDVNECREGGMVCR- 244
VCR + C+ N C+N C C G+ + G + C D++EC C
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHA 447
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
N C N G +RC+C PGY + D +C + DEC H C D N CTNT G+ C+C
Sbjct: 448 NTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNC--DENAICTNTVQGHSCTC 504
Query: 305 GAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
G+ VG + R C+E C GG C N C CP+G+ T + C K+
Sbjct: 505 KPGY--VGNGTICRAFCEE---GCRYGGTCVAPN---KCVCPSGF----TGSHC---EKD 549
Query: 364 LCYDEWEAG--RCHRARPLQLARPECCCSEGAAWGRYCE-RCPAPDSAEFMRICQGGMGR 420
+ DE G CH C W +CE R D + + +
Sbjct: 550 I--DECSEGIIECHN---------HSRCVNLPGW-YHCECRSGFHDDGTYSLSGESCI-- 595
Query: 421 PNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDG 456
D+DEC +R C C+N G F C CP G
Sbjct: 596 -----DIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 77.8 bits (183), Expect = 2e-13
Identities = 89/332 (26%), Positives = 131/332 (39%), Gaps = 47/332 (14%)
Query: 313 RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGW-RFDKTAAVC--VDE--------- 360
R C + C E P EC+N+N CEC +G+ +A C +DE
Sbjct: 387 RVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCH 446
Query: 361 RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMG- 419
+C + RC P + + C+E G C ++A QG
Sbjct: 447 ANTVCVNLPGLYRCDCV-PGYIRVDDFSCTEHDECGSGQHNCD--ENAICTNTVQGHSCT 503
Query: 420 -RPNLTQDLDECRVR-PDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCV-DADECALD 475
+P + CR + C GG CV + +C CP G+ G C D DEC+
Sbjct: 504 CKPGYVGNGTICRAFCEEGCRYGGTCVAPN---KCVCPSGFT----GSHCEKDIDECSEG 556
Query: 476 PRICGNGT-CSNTRGGYECQCSPGFTQG-----PDQTCVDVDECAEGRASC--TFRCHNT 527
C N + C N G Y C+C GF ++C+D+DECA +C C N
Sbjct: 557 IIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINL 616
Query: 528 AGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEG---YRRTS 584
AG F C CP G + + D H + Q + C +C C +G RRT+
Sbjct: 617 AGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCS------VCSCKDGKIFCRRTA 670
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDG 616
D +N D+ C E + + C++ +G
Sbjct: 671 C--DCQNPSADLFCCPECDTRVT-SQCLDQNG 699
Score = 70.1 bits (164), Expect = 3e-11
Identities = 36/101 (35%), Positives = 49/101 (48%), Gaps = 8/101 (7%)
Query: 765 CVCGPGY---RPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANC 819
C C GY + C D+DECA + C + +C N G Y C C GY + D +C
Sbjct: 416 CECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY-IRVDDFSC 474
Query: 820 RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
+ DEC H C + IC+NT + C+C+ GY G C
Sbjct: 475 TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTIC 515
Score = 68.1 bits (159), Expect = 1e-10
Identities = 42/111 (37%), Positives = 52/111 (46%), Gaps = 14/111 (12%)
Query: 756 GLC-APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYE 811
G C AP + CVC G+ G C D+DEC+ C C N G Y C CR+G+
Sbjct: 527 GTCVAPNK--CVCPSGF--TGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFH 582
Query: 812 LDE----DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGD 856
D G +C D+DEC THTC C N G ++C C G GD
Sbjct: 583 DDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGD 633
Score = 52.8 bits (121), Expect = 5e-06
Identities = 34/99 (34%), Positives = 43/99 (43%), Gaps = 14/99 (14%)
Query: 760 PGRFRCVCGPG------YRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYE 811
PG + C C G Y +GE C D+DECA+R C D C N G +DCLC +G
Sbjct: 570 PGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPS 629
Query: 812 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
D C + H Q + CSC+DG
Sbjct: 630 CSGD---CPHEGGLK---HNGQVWTLKEDRCSVCSCKDG 662
Score = 52.0 bits (119), Expect = 9e-06
Identities = 32/85 (37%), Positives = 40/85 (47%), Gaps = 13/85 (15%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGY-RPAGEVCADVDECAVRPPPCDQ--LC 795
D+DECAA C PG +RC C PGY R C + DEC CD+ +C
Sbjct: 434 DIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAIC 493
Query: 796 HNTDGSYDCLCRTGYELDEDGANCR 820
NT + C C+ GY +G CR
Sbjct: 494 TNTVQGHSCTCKPGYV--GNGTICR 516
Score = 42.3 bits (95), Expect = 0.007
Identities = 28/94 (29%), Positives = 38/94 (40%), Gaps = 13/94 (13%)
Query: 765 CVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDVD 823
C C PGY G +C E R C + C+C +G+ G++C +D+D
Sbjct: 502 CTCKPGYVGNGTICRAFCEEGCR---YGGTCVAPN---KCVCPSGFT----GSHCEKDID 551
Query: 824 ECERDTHTCQQI--CSNTEGSYECSCEDGYEKRG 855
EC C C N G Y C C G+ G
Sbjct: 552 ECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDG 585
>BC069674-1|AAH69674.1| 810|Homo sapiens nel-like 1, precursor
protein.
Length = 810
Score = 147 bits (355), Expect = 2e-34
Identities = 89/246 (36%), Positives = 114/246 (46%), Gaps = 22/246 (8%)
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGCDHGY-EHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
C P+ + C + T C C GY S C D+DEC+ C CVNL
Sbjct: 395 CAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNL 454
Query: 130 PGAFECRCPPGYRLTPSLDECEDVDECGD-QRICD-HGDCRNTIGSYRCECKPGYTLREN 187
PG + C C PGY C + DECG Q CD + C NT+ + C CKPGY
Sbjct: 455 PGLYRCDCVPGYIRVDDF-SCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGT 513
Query: 188 VCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN- 245
+CR E CR GTC P C C GF G + + D++EC EG + C N
Sbjct: 514 ICRAFCE-----EGCRYGGTCV-APNK--CVCPSGF-TGSHCE-KDIDECSEGIIECHNH 563
Query: 246 GRCRNTVGSFRCECAPGY----TLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
RC N G + CEC G+ T + G +C D+DEC H C D +C N GG++
Sbjct: 564 SRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDS--ACINLAGGFD 621
Query: 302 CSCGAG 307
C C +G
Sbjct: 622 CLCPSG 627
Score = 120 bits (289), Expect = 2e-26
Identities = 77/217 (35%), Positives = 102/217 (47%), Gaps = 21/217 (9%)
Query: 425 QDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NG 482
+D+DEC + C CVN G +RC+C GY+ D SC + DEC C N
Sbjct: 433 EDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDD-FSCTEHDECGSGQHNCDENA 491
Query: 483 TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVA 542
C+NT G+ C C PG+ G C C EG C + A + +C CP G+
Sbjct: 492 ICTNTVQGHSCTCKPGYV-GNGTICRAF--CEEG---CRYGGTCVAPN-KCVCPSGFT-- 542
Query: 543 ADGVHC-RDIDECVQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENACEDINEC 599
G HC +DIDEC + C + C N+ G Y C+C G+ S +C DI+EC
Sbjct: 543 --GSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDEC 600
Query: 600 EEQEDLC-SGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
+ C + CIN G F C C +G PS G DC
Sbjct: 601 ALRTHTCWNDSACINLAGGFDCLCPSG--PSCSG-DC 634
Score = 111 bits (268), Expect = 8e-24
Identities = 89/295 (30%), Positives = 116/295 (39%), Gaps = 52/295 (17%)
Query: 217 HCDDGFKAGPNNDCVDV----NECREGGMVCRNGRCRNTVGSFRCECAPGY-TLTADGRN 271
+C + P N C V N C EG N C+N CEC GY ++ D
Sbjct: 372 NCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAY 431
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW-KLVGRRCVDRDECKELPYVC-A 329
C D+DEC H C N C N G Y C C G+ ++ C + DEC + C
Sbjct: 432 CEDIDECAAKMHYC--HANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDE 489
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C N G+ C C G+ + T +C +E C G C +A +C C
Sbjct: 490 NAICTNTVQGHSCTCKPGYVGNGT--ICRAFCEEGCR---YGGTC-------VAPNKCVC 537
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGS 448
G G +CE+ D+DEC C RCVN G
Sbjct: 538 PSGFT-GSHCEK------------------------DIDECSEGIIECHNHSRCVNLPGW 572
Query: 449 FRCECPDGY----VLAPDGLSCVDADECALDPRICGN-GTCSNTRGGYECQCSPG 498
+ CEC G+ + G SC+D DECAL C N C N GG++C C G
Sbjct: 573 YHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 110 bits (264), Expect = 2e-23
Identities = 92/342 (26%), Positives = 126/342 (36%), Gaps = 33/342 (9%)
Query: 316 VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCH 375
VD D C+ ECR + C P D + ++C + G
Sbjct: 287 VDGDHCRNCTCKSGAVECRRMS----CP-PLNCSPDSLPVHIAGQCCKVCRPKCIYGGKV 341
Query: 376 RARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPD 435
A ++ C G + E CP + +E I + + + C P
Sbjct: 342 LAEGQRILTKSCRECRGGVLVKITEMCPPLNCSEKDHILPENQCC-RVCRGHNFCAEGPK 400
Query: 436 VCVGGRCVNTDGSFRCECPDGYV-LAPDGLSCVDADECALDPRIC-GNGTCSNTRGGYEC 493
C N + CEC GY+ + D C D DECA C N C N G Y C
Sbjct: 401 CGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRC 460
Query: 494 QCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDI 551
C PG+ + D +C + DEC G+ +C C NT CTC GY +G CR
Sbjct: 461 DCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY--VGNGTICRAF 518
Query: 552 DECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVC 611
E C + V C CP G+ + +D + E I EC C
Sbjct: 519 CE-----EGCRYG-GTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSR------C 566
Query: 612 INTDGSFLCDCDAGFEP----SEDGTDCID-----RRTGTCY 644
+N G + C+C +GF S G CID RT TC+
Sbjct: 567 VNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCW 608
Score = 100 bits (239), Expect = 3e-20
Identities = 82/261 (31%), Positives = 109/261 (41%), Gaps = 28/261 (10%)
Query: 24 CCSV--GHAWGAPCEACPPRGSPAH---TALCGEKPGEYINPVTNET--KPIDECDIMPQ 76
CC V GH + A C + A C K G YI+ + + IDEC
Sbjct: 385 CCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSG-YISVQGDSAYCEDIDECAAKMH 443
Query: 77 LCKPGT-CHDTPTGFQCGCDHGYEH-DNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFE 134
C T C + P ++C C GY D+ S C + DEC G+ C A C N
Sbjct: 444 YCHANTVCVNLPGLYRCDCVPGYIRVDDFS--CTEHDECGSGQHNCDENAICTNTVQGHS 501
Query: 135 CRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDE 194
C C PGY ++ C E G C +G + +C C G+T + +D+DE
Sbjct: 502 CTCKPGYVGNGTI--CRAFCEEG----CRYGG--TCVAPNKCVCPSGFT-GSHCEKDIDE 552
Query: 195 CSRPRPVCRNGT-CENLPGAYLCHC-----DDGFKAGPNNDCVDVNECREGGMVCRN-GR 247
CS C N + C NLPG Y C C DDG + C+D++EC C N
Sbjct: 553 CSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSA 612
Query: 248 CRNTVGSFRCECAPGYTLTAD 268
C N G F C C G + + D
Sbjct: 613 CINLAGGFDCLCPSGPSCSGD 633
Score = 97.5 bits (232), Expect = 2e-19
Identities = 85/277 (30%), Positives = 115/277 (41%), Gaps = 45/277 (16%)
Query: 188 VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA--GPNNDCVDVNECREGGMVCR- 244
VCR + C+ N C+N C C G+ + G + C D++EC C
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHA 447
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
N C N G +RC+C PGY + D +C + DEC H C D N CTNT G+ C+C
Sbjct: 448 NTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNC--DENAICTNTVQGHSCTC 504
Query: 305 GAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
G+ VG + R C+E C GG C N C CP+G+ T + C K+
Sbjct: 505 KPGY--VGNGTICRAFCEE---GCRYGGTCVAPN---KCVCPSGF----TGSHC---EKD 549
Query: 364 LCYDEWEAG--RCHRARPLQLARPECCCSEGAAWGRYCE-RCPAPDSAEFMRICQGGMGR 420
+ DE G CH C W +CE R D + + +
Sbjct: 550 I--DECSEGIIECHN---------HSRCVNLPGW-YHCECRSGFHDDGTYSLSGESCI-- 595
Query: 421 PNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDG 456
D+DEC +R C C+N G F C CP G
Sbjct: 596 -----DIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 77.8 bits (183), Expect = 2e-13
Identities = 89/332 (26%), Positives = 131/332 (39%), Gaps = 47/332 (14%)
Query: 313 RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGW-RFDKTAAVC--VDE--------- 360
R C + C E P EC+N+N CEC +G+ +A C +DE
Sbjct: 387 RVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCH 446
Query: 361 RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMG- 419
+C + RC P + + C+E G C ++A QG
Sbjct: 447 ANTVCVNLPGLYRCDCV-PGYIRVDDFSCTEHDECGSGQHNCD--ENAICTNTVQGHSCT 503
Query: 420 -RPNLTQDLDECRVR-PDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCV-DADECALD 475
+P + CR + C GG CV + +C CP G+ G C D DEC+
Sbjct: 504 CKPGYVGNGTICRAFCEEGCRYGGTCVAPN---KCVCPSGFT----GSHCEKDIDECSEG 556
Query: 476 PRICGNGT-CSNTRGGYECQCSPGFTQG-----PDQTCVDVDECAEGRASC--TFRCHNT 527
C N + C N G Y C+C GF ++C+D+DECA +C C N
Sbjct: 557 IIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINL 616
Query: 528 AGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEG---YRRTS 584
AG F C CP G + + D H + Q + C +C C +G RRT+
Sbjct: 617 AGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCS------VCSCKDGKIFCRRTA 670
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDG 616
D +N D+ C E + + C++ +G
Sbjct: 671 C--DCQNPSADLFCCPECDTRVT-SQCLDQNG 699
Score = 70.1 bits (164), Expect = 3e-11
Identities = 36/101 (35%), Positives = 49/101 (48%), Gaps = 8/101 (7%)
Query: 765 CVCGPGY---RPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANC 819
C C GY + C D+DECA + C + +C N G Y C C GY + D +C
Sbjct: 416 CECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY-IRVDDFSC 474
Query: 820 RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
+ DEC H C + IC+NT + C+C+ GY G C
Sbjct: 475 TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTIC 515
Score = 68.1 bits (159), Expect = 1e-10
Identities = 42/111 (37%), Positives = 52/111 (46%), Gaps = 14/111 (12%)
Query: 756 GLC-APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYE 811
G C AP + CVC G+ G C D+DEC+ C C N G Y C CR+G+
Sbjct: 527 GTCVAPNK--CVCPSGF--TGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFH 582
Query: 812 LDE----DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGD 856
D G +C D+DEC THTC C N G ++C C G GD
Sbjct: 583 DDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGD 633
Score = 52.8 bits (121), Expect = 5e-06
Identities = 34/99 (34%), Positives = 43/99 (43%), Gaps = 14/99 (14%)
Query: 760 PGRFRCVCGPG------YRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYE 811
PG + C C G Y +GE C D+DECA+R C D C N G +DCLC +G
Sbjct: 570 PGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPS 629
Query: 812 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
D C + H Q + CSC+DG
Sbjct: 630 CSGD---CPHEGGLK---HNGQVWTLKEDRCSVCSCKDG 662
Score = 52.0 bits (119), Expect = 9e-06
Identities = 32/85 (37%), Positives = 40/85 (47%), Gaps = 13/85 (15%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGY-RPAGEVCADVDECAVRPPPCDQ--LC 795
D+DECAA C PG +RC C PGY R C + DEC CD+ +C
Sbjct: 434 DIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAIC 493
Query: 796 HNTDGSYDCLCRTGYELDEDGANCR 820
NT + C C+ GY +G CR
Sbjct: 494 TNTVQGHSCTCKPGYV--GNGTICR 516
Score = 42.3 bits (95), Expect = 0.007
Identities = 28/94 (29%), Positives = 38/94 (40%), Gaps = 13/94 (13%)
Query: 765 CVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDVD 823
C C PGY G +C E R C + C+C +G+ G++C +D+D
Sbjct: 502 CTCKPGYVGNGTICRAFCEEGCR---YGGTCVAPN---KCVCPSGFT----GSHCEKDID 551
Query: 824 ECERDTHTCQQI--CSNTEGSYECSCEDGYEKRG 855
EC C C N G Y C C G+ G
Sbjct: 552 ECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDG 585
>U94333-1|AAB53110.1| 652|Homo sapiens C1qR(p) protein.
Length = 652
Score = 143 bits (346), Expect = 3e-33
Identities = 80/191 (41%), Positives = 102/191 (53%), Gaps = 14/191 (7%)
Query: 90 FQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGA--FECRCPPGYRLTPSL 147
F CGC G+ + C + CS PCRG A CV P + CRCP GY+L S
Sbjct: 283 FLCGCRPGFRLLDDLVTCASRNPCS--SSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340
Query: 148 DECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR---ENVCRDVDECSRPRPVCRN 204
+C DVDEC D +C NT G +RCEC GY E C+DVDEC+ R C
Sbjct: 341 LDCVDVDECQDSPCAQ--ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQ 398
Query: 205 GTCENLPGAYLCHCDDGFK-AGPNN-DCVDVNEC-REGGMVCRNGRCRNTVGSFRCECAP 261
G C N G++ C C++G+ AG + C DV+EC GG +C + C NT GSF C C P
Sbjct: 399 G-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC-DSLCFNTQGSFHCGCLP 456
Query: 262 GYTLTADGRNC 272
G+ L +G +C
Sbjct: 457 GWVLAPNGVSC 467
Score = 132 bits (319), Expect = 5e-30
Identities = 73/195 (37%), Positives = 93/195 (47%), Gaps = 12/195 (6%)
Query: 446 DGSFRCECPDGYVLAPDGLSCVDADECALDPRIC-GNGTCSNTRGG--YECQCSPGFTQG 502
DGSF C C G+ L D ++C + C+ P C G TC G Y C+C G+
Sbjct: 280 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLD 337
Query: 503 PDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVH-CRDIDECVQEPRV 560
Q CVDVDEC + + C C NT G FRC C GY G C+D+DEC
Sbjct: 338 SSQLDCVDVDECQD--SPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSP 395
Query: 561 CPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC 620
C C N GS+ C C EGY A +D C+D++EC +C NT GSF C
Sbjct: 396 CAQGCTNTDGSFHCSCEEGY--VLAGEDGTQ-CQDVDECVGPGGPLCDSLCFNTQGSFHC 452
Query: 621 DCDAGFEPSEDGTDC 635
C G+ + +G C
Sbjct: 453 GCLPGWVLAPNGVSC 467
Score = 127 bits (306), Expect = 2e-28
Identities = 77/190 (40%), Positives = 93/190 (48%), Gaps = 17/190 (8%)
Query: 402 CPAPDSAEFMRICQGGMGRPNLTQDLDECRVR----PDVCVGGR-CV-NTDG-SFRCECP 454
C F+ C+ G L DL C R C GG CV G ++ C CP
Sbjct: 275 CFEGGDGSFLCGCRPGF---RLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCP 331
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG-PDQ-TCVDVDE 512
GY L L CVD DEC P C C NT GG+ C+C G+ G P + C DVDE
Sbjct: 332 QGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDE 388
Query: 513 CAEGRASCTFRCHNTAGSFRCTCPYGYAVAA-DGVHCRDIDECV-QEPRVCPHACENVVG 570
CA GR+ C C NT GSF C+C GY +A DG C+D+DECV +C C N G
Sbjct: 389 CALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQG 448
Query: 571 SYICKCPEGY 580
S+ C C G+
Sbjct: 449 SFHCGCLPGW 458
Score = 121 bits (292), Expect = 1e-26
Identities = 73/189 (38%), Positives = 89/189 (47%), Gaps = 18/189 (9%)
Query: 131 GAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIG----SYRCECKPGYTLRE 186
G+F C C PG+RL L C + C C G +G +Y C C GY L
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP-C-RGGATCVLGPHGKNYTCRCPQGYQLDS 338
Query: 187 NV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND--CVDVNECREGGMV 242
+ C DVDEC + P + C N PG + C C G++ G + C DV+EC G
Sbjct: 339 SQLDCVDVDEC-QDSPCAQE--CVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSP 395
Query: 243 CRNGRCRNTVGSFRCECAPGYTLTA-DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
C G C NT GSF C C GY L DG C+DVDEC P G + C NT G +
Sbjct: 396 CAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC---VGPGGPLCDSLCFNTQGSFH 451
Query: 302 CSCGAGWKL 310
C C GW L
Sbjct: 452 CGCLPGWVL 460
Score = 120 bits (290), Expect = 2e-26
Identities = 75/205 (36%), Positives = 95/205 (46%), Gaps = 20/205 (9%)
Query: 164 HGDC-RNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNG-TCENLPGA--YLCH 217
H DC GS+ C C+PG+ L +++ C + CS CR G TC P Y C
Sbjct: 272 HQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCR 329
Query: 218 CDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRN-CRDV 275
C G++ + DCVDV+EC++ C C NT G FRCEC GY G C+DV
Sbjct: 330 CPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDV 386
Query: 276 DECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR---RCVDRDECKELPYVCAGGE 332
DEC PC + CTNT+G + CSC G+ L G +C D DEC
Sbjct: 387 DECALGRSPCAQ----GCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSL 442
Query: 333 CRNFNGGYVCECPAGWRFDKTAAVC 357
C N G + C C GW C
Sbjct: 443 CFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 110 bits (264), Expect = 2e-23
Identities = 56/114 (49%), Positives = 63/114 (55%), Gaps = 9/114 (7%)
Query: 747 DVDECAAIPGL--CA--PGRFRCVCGPGYRPAGE---VCADVDECAVRPPPCDQLCHNTD 799
DVDEC P C PG FRC C GY P G C DVDECA+ PC Q C NTD
Sbjct: 345 DVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTD 404
Query: 800 GSYDCLCRTGYEL-DEDGANCRDVDECERDTHT-CQQICSNTEGSYECSCEDGY 851
GS+ C C GY L EDG C+DVDEC C +C NT+GS+ C C G+
Sbjct: 405 GSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 458
Score = 99 bits (238), Expect = 3e-20
Identities = 73/214 (34%), Positives = 95/214 (44%), Gaps = 36/214 (16%)
Query: 297 NGGYECSCGAGWKLVGR--RCVDRDECKELPYVCAGGE-CRNFNGG--YVCECPAGWRFD 351
+G + C C G++L+ C R+ C P C GG C G Y C CP G++ D
Sbjct: 280 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLD 337
Query: 352 KTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFM 411
+ CVD DE + C + EC + G G CE C ++
Sbjct: 338 SSQLDCVD------VDECQDSPCAQ---------ECVNTPG---GFRCE-C-------WV 371
Query: 412 RICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLA-PDGLSCVDAD 470
GG G QD+DEC + C G C NTDGSF C C +GYVLA DG C D D
Sbjct: 372 GYEPGGPGE-GACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVD 429
Query: 471 ECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD 504
EC + C NT+G + C C PG+ P+
Sbjct: 430 ECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPN 463
Score = 95.9 bits (228), Expect = 5e-19
Identities = 63/168 (37%), Positives = 79/168 (47%), Gaps = 14/168 (8%)
Query: 24 CCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTC 83
C S GA C P G +T C + G ++ + +DEC P C C
Sbjct: 306 CSSSPCRGGATC-VLGPHGKN-YTCRCPQ--GYQLDSSQLDCVDVDECQDSP--CAQ-EC 358
Query: 84 HDTPTGFQCGCDHGYEHDNTSH-LCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
+TP GF+C C GYE C+DVDEC+ GR PC C N G+F C C GY
Sbjct: 359 VNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPC--AQGCTNTDGSFHCSCEEGYV 416
Query: 143 LT-PSLDECEDVDEC--GDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
L +C+DVDEC +CD C NT GS+ C C PG+ L N
Sbjct: 417 LAGEDGTQCQDVDECVGPGGPLCD-SLCFNTQGSFHCGCLPGWVLAPN 463
Score = 89.8 bits (213), Expect = 4e-17
Identities = 43/97 (44%), Positives = 56/97 (57%), Gaps = 5/97 (5%)
Query: 763 FRCVCGPGYR-PAGEV-CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN-C 819
+ C C GY+ + ++ C DVDEC + PC Q C NT G + C C GYE G C
Sbjct: 326 YTCRCPQGYQLDSSQLDCVDVDEC--QDSPCAQECVNTPGGFRCECWVGYEPGGPGEGAC 383
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
+DVDEC C Q C+NT+GS+ CSCE+GY G+
Sbjct: 384 QDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGE 420
Score = 84.6 bits (200), Expect = 1e-15
Identities = 74/218 (33%), Positives = 94/218 (43%), Gaps = 35/218 (16%)
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG-GYECSCGAGWKLV 311
GSF C C PG+ L D C + C PC R G +G Y C C G++L
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSS--SPC-RGGATCVLGPHGKNYTCRCPQGYQLD 337
Query: 312 GRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTA-AVCVDERKELCYDE 368
+ CVD DEC++ P CA EC N GG+ CEC G+ C D DE
Sbjct: 338 SSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQD------VDE 388
Query: 369 WEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLD 428
GR A+ C ++G+ +C S E + G G QD+D
Sbjct: 389 CALGRSPCAQG-------CTNTDGSF---HC-------SCEEGYVLAGEDGTQ--CQDVD 429
Query: 429 ECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
EC C NT GSF C C G+VLAP+G+SC
Sbjct: 430 ECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 80.2 bits (189), Expect = 3e-14
Identities = 51/155 (32%), Positives = 68/155 (43%), Gaps = 18/155 (11%)
Query: 202 CRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECRE----GGMVCRNGRCRNTVGSFR 256
C E G++LC C GF+ + C N C GG C G ++
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGK---NYT 327
Query: 257 CECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG---R 313
C C GY L + +C DVDEC + PC ++ C NT GG+ C C G++ G
Sbjct: 328 CRCPQGYQLDSSQLDCVDVDECQD--SPCAQE----CVNTPGGFRCECWVGYEPGGPGEG 381
Query: 314 RCVDRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
C D DEC CA G C N +G + C C G+
Sbjct: 382 ACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGY 415
Score = 69.7 bits (163), Expect = 4e-11
Identities = 38/99 (38%), Positives = 48/99 (48%), Gaps = 6/99 (6%)
Query: 761 GRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCH-NTDG-SYDCLCRTGYELDEDG 816
G F C C PG+R ++ CA + C+ P C G +Y C C GY+LD
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340
Query: 817 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
+C DVDEC+ C Q C NT G + C C GYE G
Sbjct: 341 LDCVDVDECQ--DSPCAQECVNTPGGFRCECWVGYEPGG 377
Score = 66.9 bits (156), Expect = 3e-10
Identities = 40/84 (47%), Positives = 44/84 (52%), Gaps = 12/84 (14%)
Query: 747 DVDECAAIPGLCAPG------RFRCVCGPGYRPAGE---VCADVDECAVRP--PPCDQLC 795
DVDECA CA G F C C GY AGE C DVDEC V P P CD LC
Sbjct: 385 DVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC-VGPGGPLCDSLC 443
Query: 796 HNTDGSYDCLCRTGYELDEDGANC 819
NT GS+ C C G+ L +G +C
Sbjct: 444 FNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 36.7 bits (81), Expect = 0.35
Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
Query: 791 CDQLC-HNTDGSYDCLCRTGYELDEDGANCRDVDECE----RDTHTCQQICSNTEGSYEC 845
C Q C DGS+ C CR G+ L +D C + C R TC + +Y C
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATC--VLGPHGKNYTC 328
Query: 846 SCEDGYE 852
C GY+
Sbjct: 329 RCPQGYQ 335
Score = 35.5 bits (78), Expect = 0.81
Identities = 24/81 (29%), Positives = 33/81 (40%), Gaps = 10/81 (12%)
Query: 561 CPHAC-ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CI-NTDG- 616
C C E GS++C C G+R D C N C C GG C+ G
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLL----DDLVTCASRNPCSSSP--CRGGATCVLGPHGK 324
Query: 617 SFLCDCDAGFEPSEDGTDCID 637
++ C C G++ DC+D
Sbjct: 325 NYTCRCPQGYQLDSSQLDCVD 345
>BC028075-1|AAH28075.1| 652|Homo sapiens CD93 molecule protein.
Length = 652
Score = 143 bits (346), Expect = 3e-33
Identities = 80/191 (41%), Positives = 102/191 (53%), Gaps = 14/191 (7%)
Query: 90 FQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGA--FECRCPPGYRLTPSL 147
F CGC G+ + C + CS PCRG A CV P + CRCP GY+L S
Sbjct: 283 FLCGCRPGFRLLDDLVTCASRNPCS--SSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340
Query: 148 DECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR---ENVCRDVDECSRPRPVCRN 204
+C DVDEC D +C NT G +RCEC GY E C+DVDEC+ R C
Sbjct: 341 LDCVDVDECQDSPCAQ--ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQ 398
Query: 205 GTCENLPGAYLCHCDDGFK-AGPNN-DCVDVNEC-REGGMVCRNGRCRNTVGSFRCECAP 261
G C N G++ C C++G+ AG + C DV+EC GG +C + C NT GSF C C P
Sbjct: 399 G-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC-DSLCFNTQGSFHCGCLP 456
Query: 262 GYTLTADGRNC 272
G+ L +G +C
Sbjct: 457 GWVLAPNGVSC 467
Score = 132 bits (319), Expect = 5e-30
Identities = 73/195 (37%), Positives = 93/195 (47%), Gaps = 12/195 (6%)
Query: 446 DGSFRCECPDGYVLAPDGLSCVDADECALDPRIC-GNGTCSNTRGG--YECQCSPGFTQG 502
DGSF C C G+ L D ++C + C+ P C G TC G Y C+C G+
Sbjct: 280 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLD 337
Query: 503 PDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVH-CRDIDECVQEPRV 560
Q CVDVDEC + + C C NT G FRC C GY G C+D+DEC
Sbjct: 338 SSQLDCVDVDECQD--SPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSP 395
Query: 561 CPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC 620
C C N GS+ C C EGY A +D C+D++EC +C NT GSF C
Sbjct: 396 CAQGCTNTDGSFHCSCEEGY--VLAGEDGTQ-CQDVDECVGPGGPLCDSLCFNTQGSFHC 452
Query: 621 DCDAGFEPSEDGTDC 635
C G+ + +G C
Sbjct: 453 GCLPGWVLAPNGVSC 467
Score = 127 bits (306), Expect = 2e-28
Identities = 77/190 (40%), Positives = 93/190 (48%), Gaps = 17/190 (8%)
Query: 402 CPAPDSAEFMRICQGGMGRPNLTQDLDECRVR----PDVCVGGR-CV-NTDG-SFRCECP 454
C F+ C+ G L DL C R C GG CV G ++ C CP
Sbjct: 275 CFEGGDGSFLCGCRPGF---RLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCP 331
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG-PDQ-TCVDVDE 512
GY L L CVD DEC P C C NT GG+ C+C G+ G P + C DVDE
Sbjct: 332 QGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDE 388
Query: 513 CAEGRASCTFRCHNTAGSFRCTCPYGYAVAA-DGVHCRDIDECV-QEPRVCPHACENVVG 570
CA GR+ C C NT GSF C+C GY +A DG C+D+DECV +C C N G
Sbjct: 389 CALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQG 448
Query: 571 SYICKCPEGY 580
S+ C C G+
Sbjct: 449 SFHCGCLPGW 458
Score = 121 bits (292), Expect = 1e-26
Identities = 73/189 (38%), Positives = 89/189 (47%), Gaps = 18/189 (9%)
Query: 131 GAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIG----SYRCECKPGYTLRE 186
G+F C C PG+RL L C + C C G +G +Y C C GY L
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP-C-RGGATCVLGPHGKNYTCRCPQGYQLDS 338
Query: 187 NV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND--CVDVNECREGGMV 242
+ C DVDEC + P + C N PG + C C G++ G + C DV+EC G
Sbjct: 339 SQLDCVDVDEC-QDSPCAQE--CVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSP 395
Query: 243 CRNGRCRNTVGSFRCECAPGYTLTA-DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
C G C NT GSF C C GY L DG C+DVDEC P G + C NT G +
Sbjct: 396 CAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC---VGPGGPLCDSLCFNTQGSFH 451
Query: 302 CSCGAGWKL 310
C C GW L
Sbjct: 452 CGCLPGWVL 460
Score = 120 bits (290), Expect = 2e-26
Identities = 75/205 (36%), Positives = 95/205 (46%), Gaps = 20/205 (9%)
Query: 164 HGDC-RNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNG-TCENLPGA--YLCH 217
H DC GS+ C C+PG+ L +++ C + CS CR G TC P Y C
Sbjct: 272 HQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCR 329
Query: 218 CDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRN-CRDV 275
C G++ + DCVDV+EC++ C C NT G FRCEC GY G C+DV
Sbjct: 330 CPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDV 386
Query: 276 DECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR---RCVDRDECKELPYVCAGGE 332
DEC PC + CTNT+G + CSC G+ L G +C D DEC
Sbjct: 387 DECALGRSPCAQ----GCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSL 442
Query: 333 CRNFNGGYVCECPAGWRFDKTAAVC 357
C N G + C C GW C
Sbjct: 443 CFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 110 bits (264), Expect = 2e-23
Identities = 56/114 (49%), Positives = 63/114 (55%), Gaps = 9/114 (7%)
Query: 747 DVDECAAIPGL--CA--PGRFRCVCGPGYRPAGE---VCADVDECAVRPPPCDQLCHNTD 799
DVDEC P C PG FRC C GY P G C DVDECA+ PC Q C NTD
Sbjct: 345 DVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTD 404
Query: 800 GSYDCLCRTGYEL-DEDGANCRDVDECERDTHT-CQQICSNTEGSYECSCEDGY 851
GS+ C C GY L EDG C+DVDEC C +C NT+GS+ C C G+
Sbjct: 405 GSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 458
Score = 99 bits (238), Expect = 3e-20
Identities = 73/214 (34%), Positives = 95/214 (44%), Gaps = 36/214 (16%)
Query: 297 NGGYECSCGAGWKLVGR--RCVDRDECKELPYVCAGGE-CRNFNGG--YVCECPAGWRFD 351
+G + C C G++L+ C R+ C P C GG C G Y C CP G++ D
Sbjct: 280 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLD 337
Query: 352 KTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFM 411
+ CVD DE + C + EC + G G CE C ++
Sbjct: 338 SSQLDCVD------VDECQDSPCAQ---------ECVNTPG---GFRCE-C-------WV 371
Query: 412 RICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLA-PDGLSCVDAD 470
GG G QD+DEC + C G C NTDGSF C C +GYVLA DG C D D
Sbjct: 372 GYEPGGPGE-GACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVD 429
Query: 471 ECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD 504
EC + C NT+G + C C PG+ P+
Sbjct: 430 ECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPN 463
Score = 95.9 bits (228), Expect = 5e-19
Identities = 63/168 (37%), Positives = 79/168 (47%), Gaps = 14/168 (8%)
Query: 24 CCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTC 83
C S GA C P G +T C + G ++ + +DEC P C C
Sbjct: 306 CSSSPCRGGATC-VLGPHGKN-YTCRCPQ--GYQLDSSQLDCVDVDECQDSP--CAQ-EC 358
Query: 84 HDTPTGFQCGCDHGYEHDNTSH-LCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
+TP GF+C C GYE C+DVDEC+ GR PC C N G+F C C GY
Sbjct: 359 VNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPC--AQGCTNTDGSFHCSCEEGYV 416
Query: 143 LT-PSLDECEDVDEC--GDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
L +C+DVDEC +CD C NT GS+ C C PG+ L N
Sbjct: 417 LAGEDGTQCQDVDECVGPGGPLCD-SLCFNTQGSFHCGCLPGWVLAPN 463
Score = 89.8 bits (213), Expect = 4e-17
Identities = 43/97 (44%), Positives = 56/97 (57%), Gaps = 5/97 (5%)
Query: 763 FRCVCGPGYR-PAGEV-CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN-C 819
+ C C GY+ + ++ C DVDEC + PC Q C NT G + C C GYE G C
Sbjct: 326 YTCRCPQGYQLDSSQLDCVDVDEC--QDSPCAQECVNTPGGFRCECWVGYEPGGPGEGAC 383
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
+DVDEC C Q C+NT+GS+ CSCE+GY G+
Sbjct: 384 QDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGE 420
Score = 84.6 bits (200), Expect = 1e-15
Identities = 74/218 (33%), Positives = 94/218 (43%), Gaps = 35/218 (16%)
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG-GYECSCGAGWKLV 311
GSF C C PG+ L D C + C PC R G +G Y C C G++L
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSS--SPC-RGGATCVLGPHGKNYTCRCPQGYQLD 337
Query: 312 GRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTA-AVCVDERKELCYDE 368
+ CVD DEC++ P CA EC N GG+ CEC G+ C D DE
Sbjct: 338 SSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQD------VDE 388
Query: 369 WEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLD 428
GR A+ C ++G+ +C S E + G G QD+D
Sbjct: 389 CALGRSPCAQG-------CTNTDGSF---HC-------SCEEGYVLAGEDGTQ--CQDVD 429
Query: 429 ECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
EC C NT GSF C C G+VLAP+G+SC
Sbjct: 430 ECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 80.2 bits (189), Expect = 3e-14
Identities = 51/155 (32%), Positives = 68/155 (43%), Gaps = 18/155 (11%)
Query: 202 CRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECRE----GGMVCRNGRCRNTVGSFR 256
C E G++LC C GF+ + C N C GG C G ++
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGK---NYT 327
Query: 257 CECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG---R 313
C C GY L + +C DVDEC + PC ++ C NT GG+ C C G++ G
Sbjct: 328 CRCPQGYQLDSSQLDCVDVDECQD--SPCAQE----CVNTPGGFRCECWVGYEPGGPGEG 381
Query: 314 RCVDRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
C D DEC CA G C N +G + C C G+
Sbjct: 382 ACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGY 415
Score = 69.7 bits (163), Expect = 4e-11
Identities = 38/99 (38%), Positives = 48/99 (48%), Gaps = 6/99 (6%)
Query: 761 GRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCH-NTDG-SYDCLCRTGYELDEDG 816
G F C C PG+R ++ CA + C+ P C G +Y C C GY+LD
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340
Query: 817 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
+C DVDEC+ C Q C NT G + C C GYE G
Sbjct: 341 LDCVDVDECQ--DSPCAQECVNTPGGFRCECWVGYEPGG 377
Score = 66.9 bits (156), Expect = 3e-10
Identities = 40/84 (47%), Positives = 44/84 (52%), Gaps = 12/84 (14%)
Query: 747 DVDECAAIPGLCAPG------RFRCVCGPGYRPAGE---VCADVDECAVRP--PPCDQLC 795
DVDECA CA G F C C GY AGE C DVDEC V P P CD LC
Sbjct: 385 DVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC-VGPGGPLCDSLC 443
Query: 796 HNTDGSYDCLCRTGYELDEDGANC 819
NT GS+ C C G+ L +G +C
Sbjct: 444 FNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 36.7 bits (81), Expect = 0.35
Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
Query: 791 CDQLC-HNTDGSYDCLCRTGYELDEDGANCRDVDECE----RDTHTCQQICSNTEGSYEC 845
C Q C DGS+ C CR G+ L +D C + C R TC + +Y C
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATC--VLGPHGKNYTC 328
Query: 846 SCEDGYE 852
C GY+
Sbjct: 329 RCPQGYQ 335
Score = 35.5 bits (78), Expect = 0.81
Identities = 24/81 (29%), Positives = 33/81 (40%), Gaps = 10/81 (12%)
Query: 561 CPHAC-ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CI-NTDG- 616
C C E GS++C C G+R D C N C C GG C+ G
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLL----DDLVTCASRNPCSSSP--CRGGATCVLGPHGK 324
Query: 617 SFLCDCDAGFEPSEDGTDCID 637
++ C C G++ DC+D
Sbjct: 325 NYTCRCPQGYQLDSSQLDCVD 345
>AY358336-1|AAQ88702.1| 509|Homo sapiens DFLL295 protein.
Length = 509
Score = 143 bits (346), Expect = 3e-33
Identities = 83/176 (47%), Positives = 99/176 (56%), Gaps = 13/176 (7%)
Query: 414 CQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
C G QDL+EC ++P C RC+NT GS++C C +GY+L PDG SC A C+
Sbjct: 77 CHPGYAGKTCNQDLNECGLKPRPCKH-RCMNTYGSYKCYCLNGYMLMPDG-SCSSALTCS 134
Query: 474 LDPRICGNGTCSNTRGGYECQC-SPGFTQGPD-QTCVDVDECAEGRASC-TFR-CHNTAG 529
+ C G C +G CQC SPG PD +TCVDVDECA GRASC FR C NT G
Sbjct: 135 M--ANCQYG-CDVVKGQIRCQCPSPGLHLAPDGRTCVDVDECATGRASCPRFRQCVNTFG 191
Query: 530 SFRCTCPYGYAVAADG--VHCRDIDECVQEPRVCPH--ACENVVGSYICKCPEGYR 581
S+ C C G+ + G C DIDEC C C NV GSY CKC EGY+
Sbjct: 192 SYICKCHKGFDLMYIGGKYQCHDIDECSLGQYQCSSFARCYNVRGSYKCKCKEGYQ 247
Score = 132 bits (319), Expect = 5e-30
Identities = 81/228 (35%), Positives = 106/228 (46%), Gaps = 22/228 (9%)
Query: 414 CQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADEC 472
C G R + Q C+ R C G C+ G +C+C GY G +C D +EC
Sbjct: 44 CCWGWARQSWGQCQPVCQPR---CKHGECI---GPNKCKCHPGYA----GKTCNQDLNEC 93
Query: 473 ALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
L PR C + C NT G Y+C C G+ PD +C C+ A+C + C G R
Sbjct: 94 GLKPRPCKH-RCMNTYGSYKCYCLNGYMLMPDGSCSSALTCS--MANCQYGCDVVKGQIR 150
Query: 533 CTCPY-GYAVAADGVHCRDIDECVQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDS 589
C CP G +A DG C D+DEC CP C N GSYICKC +G+
Sbjct: 151 CQCPSPGLHLAPDGRTCVDVDECATGRASCPRFRQCVNTFGSYICKCHKGFDLMYI--GG 208
Query: 590 ENACEDINECEEQEDLCSGGV-CINTDGSFLCDCDAGFEPSEDGTDCI 636
+ C DI+EC + CS C N GS+ C C G++ DG C+
Sbjct: 209 KYQCHDIDECSLGQYQCSSFARCYNVRGSYKCKCKEGYQ--GDGLTCV 254
Score = 127 bits (306), Expect = 2e-28
Identities = 75/204 (36%), Positives = 102/204 (50%), Gaps = 18/204 (8%)
Query: 162 CDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECS-RPRPVCRNGTCENLPGAYLCHCDD 220
C HG+C IG +C+C PGY + +D++EC +PRP C++ C N G+Y C+C +
Sbjct: 64 CKHGEC---IGPNKCKCHPGYA-GKTCNQDLNECGLKPRP-CKH-RCMNTYGSYKCYCLN 117
Query: 221 GFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCEC-APGYTLTADGRNCRDVDECD 279
G+ P+ C C C+ G C G RC+C +PG L DGR C DVDEC
Sbjct: 118 GYMLMPDGSCSSALTCSMAN--CQYG-CDVVKGQIRCQCPSPGLHLAPDGRTCVDVDECA 174
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV---GR-RCVDRDECKELPYVCAG-GECR 334
C R C NT G Y C C G+ L+ G+ +C D DEC Y C+ C
Sbjct: 175 TGRASCPRFRQ--CVNTFGSYICKCHKGFDLMYIGGKYQCHDIDECSLGQYQCSSFARCY 232
Query: 335 NFNGGYVCECPAGWRFDKTAAVCV 358
N G Y C+C G++ D V +
Sbjct: 233 NVRGSYKCKCKEGYQGDGLTCVYI 256
Score = 117 bits (282), Expect = 2e-25
Identities = 76/213 (35%), Positives = 101/213 (47%), Gaps = 20/213 (9%)
Query: 114 SWGR--PPCRGMAQCVNLPGAFECRCPPGYRLTPSLDEC-EDVDECG-DQRICDHGDCRN 169
SWG+ P C+ + G +C+C PGY + C +D++ECG R C H C N
Sbjct: 52 SWGQCQPVCQPRCKHGECIGPNKCKCHPGY----AGKTCNQDLNECGLKPRPCKHR-CMN 106
Query: 170 TIGSYRCECKPGYTLR-ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHC-DDGFKAGPN 227
T GSY+C C GY L + C CS C+ G C+ + G C C G P+
Sbjct: 107 TYGSYKCYCLNGYMLMPDGSCSSALTCSMAN--CQYG-CDVVKGQIRCQCPSPGLHLAPD 163
Query: 228 -NDCVDVNECREGGMVC-RNGRCRNTVGSFRCECAPGYTLTADG--RNCRDVDECDELPH 283
CVDV+EC G C R +C NT GS+ C+C G+ L G C D+DEC +
Sbjct: 164 GRTCVDVDECATGRASCPRFRQCVNTFGSYICKCHKGFDLMYIGGKYQCHDIDECSLGQY 223
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV 316
C C N G Y+C C G++ G CV
Sbjct: 224 QCSSFAR--CYNVRGSYKCKCKEGYQGDGLTCV 254
Score = 89.4 bits (212), Expect = 5e-17
Identities = 45/108 (41%), Positives = 55/108 (50%), Gaps = 9/108 (8%)
Query: 761 GRFRCVC-GPGYR--PAGEVCADVDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDED 815
G+ RC C PG P G C DVDECA C + C NT GSY C C G++L
Sbjct: 147 GQIRCQCPSPGLHLAPDGRTCVDVDECATGRASCPRFRQCVNTFGSYICKCHKGFDLMYI 206
Query: 816 GAN--CRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACV 859
G C D+DEC + C C N GSY+C C++GY+ G CV
Sbjct: 207 GGKYQCHDIDECSLGQYQCSSFARCYNVRGSYKCKCKEGYQGDGLTCV 254
Score = 75.8 bits (178), Expect = 6e-13
Identities = 63/202 (31%), Positives = 80/202 (39%), Gaps = 25/202 (12%)
Query: 199 RPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCE 258
+P C++G C G C C G+ N D+NEC C++ RC NT GS++C
Sbjct: 61 QPRCKHGECI---GPNKCKCHPGYAGKTCNQ--DLNECGLKPRPCKH-RCMNTYGSYKCY 114
Query: 259 CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC-GAGWKLV--GRRC 315
C GY L DG +C C G C G C C G L GR C
Sbjct: 115 CLNGYMLMPDG-SCSSALTCSMANCQYG------CDVVKGQIRCQCPSPGLHLAPDGRTC 167
Query: 316 VDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRF----DKTAAVCVDERKELCYDEWE 370
VD DEC C +C N G Y+C+C G+ K +DE Y
Sbjct: 168 VDVDECATGRASCPRFRQCVNTFGSYICKCHKGFDLMYIGGKYQCHDIDECSLGQYQCSS 227
Query: 371 AGRCHRARPLQLARPECCCSEG 392
RC+ R +C C EG
Sbjct: 228 FARCYNVR----GSYKCKCKEG 245
Score = 74.9 bits (176), Expect = 1e-12
Identities = 40/110 (36%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 78 CKPGTCHDTPTGFQCGCDH-GYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECR 136
C+ G C +C C G C DVDEC+ GR C QCVN G++ C+
Sbjct: 138 CQYG-CDVVKGQIRCQCPSPGLHLAPDGRTCVDVDECATGRASCPRFRQCVNTFGSYICK 196
Query: 137 CPPGYRL--TPSLDECEDVDEC--GDQRICDHGDCRNTIGSYRCECKPGY 182
C G+ L +C D+DEC G + C N GSY+C+CK GY
Sbjct: 197 CHKGFDLMYIGGKYQCHDIDECSLGQYQCSSFARCYNVRGSYKCKCKEGY 246
Score = 72.1 bits (169), Expect = 8e-12
Identities = 36/88 (40%), Positives = 44/88 (50%), Gaps = 6/88 (6%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G +C C PGY AG+ C D++EC ++P PC C NT GSY C C GY L DG +C
Sbjct: 71 GPNKCKCHPGY--AGKTCNQDLNECGLKPRPCKHRCMNTYGSYKCYCLNGYMLMPDG-SC 127
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSC 847
C CQ C +G C C
Sbjct: 128 SSALTC--SMANCQYGCDVVKGQIRCQC 153
Score = 60.9 bits (141), Expect = 2e-08
Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 3/92 (3%)
Query: 54 PGEYINPVTNETKPIDECDIMPQLC-KPGTCHDTPTGFQCGCDHGYE--HDNTSHLCRDV 110
PG ++ P +DEC C + C +T + C C G++ + + C D+
Sbjct: 156 PGLHLAPDGRTCVDVDECATGRASCPRFRQCVNTFGSYICKCHKGFDLMYIGGKYQCHDI 215
Query: 111 DECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
DECS G+ C A+C N+ G+++C+C GY+
Sbjct: 216 DECSLGQYQCSSFARCYNVRGSYKCKCKEGYQ 247
Score = 59.3 bits (137), Expect = 6e-08
Identities = 40/122 (32%), Positives = 51/122 (41%), Gaps = 16/122 (13%)
Query: 520 CTFRCHN--TAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVCPHACENVVGSYICKC 576
C RC + G +C C GYA G C +D++EC +PR C H C N GSY C C
Sbjct: 60 CQPRCKHGECIGPNKCKCHPGYA----GKTCNQDLNECGLKPRPCKHRCMNTYGSYKCYC 115
Query: 577 PEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDA-GFEPSEDGTDC 635
GY + +C C C G C G C C + G + DG C
Sbjct: 116 LNGYMLM-----PDGSCSSALTCSMAN--CQYG-CDVVKGQIRCQCPSPGLHLAPDGRTC 167
Query: 636 ID 637
+D
Sbjct: 168 VD 169
Score = 47.2 bits (107), Expect = 2e-04
Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 7/66 (10%)
Query: 789 PPCDQLCHNTD--GSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYEC 845
P C C + + G C C GY G C +D++EC C+ C NT GSY+C
Sbjct: 58 PVCQPRCKHGECIGPNKCKCHPGYA----GKTCNQDLNECGLKPRPCKHRCMNTYGSYKC 113
Query: 846 SCEDGY 851
C +GY
Sbjct: 114 YCLNGY 119
>AL118508-1|CAC00597.1| 652|Homo sapiens complement component 1, q
subcomponent, receptor 1 protein.
Length = 652
Score = 143 bits (346), Expect = 3e-33
Identities = 80/191 (41%), Positives = 102/191 (53%), Gaps = 14/191 (7%)
Query: 90 FQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGA--FECRCPPGYRLTPSL 147
F CGC G+ + C + CS PCRG A CV P + CRCP GY+L S
Sbjct: 283 FLCGCRPGFRLLDDLVTCASRNPCS--SSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340
Query: 148 DECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR---ENVCRDVDECSRPRPVCRN 204
+C DVDEC D +C NT G +RCEC GY E C+DVDEC+ R C
Sbjct: 341 LDCVDVDECQDSPCAQ--ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQ 398
Query: 205 GTCENLPGAYLCHCDDGFK-AGPNN-DCVDVNEC-REGGMVCRNGRCRNTVGSFRCECAP 261
G C N G++ C C++G+ AG + C DV+EC GG +C + C NT GSF C C P
Sbjct: 399 G-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC-DSLCFNTQGSFHCGCLP 456
Query: 262 GYTLTADGRNC 272
G+ L +G +C
Sbjct: 457 GWVLAPNGVSC 467
Score = 132 bits (319), Expect = 5e-30
Identities = 73/195 (37%), Positives = 93/195 (47%), Gaps = 12/195 (6%)
Query: 446 DGSFRCECPDGYVLAPDGLSCVDADECALDPRIC-GNGTCSNTRGG--YECQCSPGFTQG 502
DGSF C C G+ L D ++C + C+ P C G TC G Y C+C G+
Sbjct: 280 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLD 337
Query: 503 PDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVH-CRDIDECVQEPRV 560
Q CVDVDEC + + C C NT G FRC C GY G C+D+DEC
Sbjct: 338 SSQLDCVDVDECQD--SPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSP 395
Query: 561 CPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC 620
C C N GS+ C C EGY A +D C+D++EC +C NT GSF C
Sbjct: 396 CAQGCTNTDGSFHCSCEEGY--VLAGEDGTQ-CQDVDECVGPGGPLCDSLCFNTQGSFHC 452
Query: 621 DCDAGFEPSEDGTDC 635
C G+ + +G C
Sbjct: 453 GCLPGWVLAPNGVSC 467
Score = 127 bits (306), Expect = 2e-28
Identities = 77/190 (40%), Positives = 93/190 (48%), Gaps = 17/190 (8%)
Query: 402 CPAPDSAEFMRICQGGMGRPNLTQDLDECRVR----PDVCVGGR-CV-NTDG-SFRCECP 454
C F+ C+ G L DL C R C GG CV G ++ C CP
Sbjct: 275 CFEGGDGSFLCGCRPGF---RLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCP 331
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG-PDQ-TCVDVDE 512
GY L L CVD DEC P C C NT GG+ C+C G+ G P + C DVDE
Sbjct: 332 QGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDE 388
Query: 513 CAEGRASCTFRCHNTAGSFRCTCPYGYAVAA-DGVHCRDIDECV-QEPRVCPHACENVVG 570
CA GR+ C C NT GSF C+C GY +A DG C+D+DECV +C C N G
Sbjct: 389 CALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQG 448
Query: 571 SYICKCPEGY 580
S+ C C G+
Sbjct: 449 SFHCGCLPGW 458
Score = 121 bits (292), Expect = 1e-26
Identities = 73/189 (38%), Positives = 89/189 (47%), Gaps = 18/189 (9%)
Query: 131 GAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIG----SYRCECKPGYTLRE 186
G+F C C PG+RL L C + C C G +G +Y C C GY L
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP-C-RGGATCVLGPHGKNYTCRCPQGYQLDS 338
Query: 187 NV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND--CVDVNECREGGMV 242
+ C DVDEC + P + C N PG + C C G++ G + C DV+EC G
Sbjct: 339 SQLDCVDVDEC-QDSPCAQE--CVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSP 395
Query: 243 CRNGRCRNTVGSFRCECAPGYTLTA-DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
C G C NT GSF C C GY L DG C+DVDEC P G + C NT G +
Sbjct: 396 CAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC---VGPGGPLCDSLCFNTQGSFH 451
Query: 302 CSCGAGWKL 310
C C GW L
Sbjct: 452 CGCLPGWVL 460
Score = 120 bits (290), Expect = 2e-26
Identities = 75/205 (36%), Positives = 95/205 (46%), Gaps = 20/205 (9%)
Query: 164 HGDC-RNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNG-TCENLPGA--YLCH 217
H DC GS+ C C+PG+ L +++ C + CS CR G TC P Y C
Sbjct: 272 HQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCR 329
Query: 218 CDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRN-CRDV 275
C G++ + DCVDV+EC++ C C NT G FRCEC GY G C+DV
Sbjct: 330 CPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDV 386
Query: 276 DECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR---RCVDRDECKELPYVCAGGE 332
DEC PC + CTNT+G + CSC G+ L G +C D DEC
Sbjct: 387 DECALGRSPCAQ----GCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSL 442
Query: 333 CRNFNGGYVCECPAGWRFDKTAAVC 357
C N G + C C GW C
Sbjct: 443 CFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 110 bits (264), Expect = 2e-23
Identities = 56/114 (49%), Positives = 63/114 (55%), Gaps = 9/114 (7%)
Query: 747 DVDECAAIPGL--CA--PGRFRCVCGPGYRPAGE---VCADVDECAVRPPPCDQLCHNTD 799
DVDEC P C PG FRC C GY P G C DVDECA+ PC Q C NTD
Sbjct: 345 DVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTD 404
Query: 800 GSYDCLCRTGYEL-DEDGANCRDVDECERDTHT-CQQICSNTEGSYECSCEDGY 851
GS+ C C GY L EDG C+DVDEC C +C NT+GS+ C C G+
Sbjct: 405 GSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 458
Score = 99 bits (238), Expect = 3e-20
Identities = 73/214 (34%), Positives = 95/214 (44%), Gaps = 36/214 (16%)
Query: 297 NGGYECSCGAGWKLVGR--RCVDRDECKELPYVCAGGE-CRNFNGG--YVCECPAGWRFD 351
+G + C C G++L+ C R+ C P C GG C G Y C CP G++ D
Sbjct: 280 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLD 337
Query: 352 KTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFM 411
+ CVD DE + C + EC + G G CE C ++
Sbjct: 338 SSQLDCVD------VDECQDSPCAQ---------ECVNTPG---GFRCE-C-------WV 371
Query: 412 RICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLA-PDGLSCVDAD 470
GG G QD+DEC + C G C NTDGSF C C +GYVLA DG C D D
Sbjct: 372 GYEPGGPGE-GACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVD 429
Query: 471 ECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD 504
EC + C NT+G + C C PG+ P+
Sbjct: 430 ECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPN 463
Score = 95.9 bits (228), Expect = 5e-19
Identities = 63/168 (37%), Positives = 79/168 (47%), Gaps = 14/168 (8%)
Query: 24 CCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTC 83
C S GA C P G +T C + G ++ + +DEC P C C
Sbjct: 306 CSSSPCRGGATC-VLGPHGKN-YTCRCPQ--GYQLDSSQLDCVDVDECQDSP--CAQ-EC 358
Query: 84 HDTPTGFQCGCDHGYEHDNTSH-LCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
+TP GF+C C GYE C+DVDEC+ GR PC C N G+F C C GY
Sbjct: 359 VNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPC--AQGCTNTDGSFHCSCEEGYV 416
Query: 143 LT-PSLDECEDVDEC--GDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
L +C+DVDEC +CD C NT GS+ C C PG+ L N
Sbjct: 417 LAGEDGTQCQDVDECVGPGGPLCD-SLCFNTQGSFHCGCLPGWVLAPN 463
Score = 89.8 bits (213), Expect = 4e-17
Identities = 43/97 (44%), Positives = 56/97 (57%), Gaps = 5/97 (5%)
Query: 763 FRCVCGPGYR-PAGEV-CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN-C 819
+ C C GY+ + ++ C DVDEC + PC Q C NT G + C C GYE G C
Sbjct: 326 YTCRCPQGYQLDSSQLDCVDVDEC--QDSPCAQECVNTPGGFRCECWVGYEPGGPGEGAC 383
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
+DVDEC C Q C+NT+GS+ CSCE+GY G+
Sbjct: 384 QDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGE 420
Score = 84.6 bits (200), Expect = 1e-15
Identities = 74/218 (33%), Positives = 94/218 (43%), Gaps = 35/218 (16%)
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG-GYECSCGAGWKLV 311
GSF C C PG+ L D C + C PC R G +G Y C C G++L
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSS--SPC-RGGATCVLGPHGKNYTCRCPQGYQLD 337
Query: 312 GRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTA-AVCVDERKELCYDE 368
+ CVD DEC++ P CA EC N GG+ CEC G+ C D DE
Sbjct: 338 SSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQD------VDE 388
Query: 369 WEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLD 428
GR A+ C ++G+ +C S E + G G QD+D
Sbjct: 389 CALGRSPCAQG-------CTNTDGSF---HC-------SCEEGYVLAGEDGTQ--CQDVD 429
Query: 429 ECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
EC C NT GSF C C G+VLAP+G+SC
Sbjct: 430 ECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 80.2 bits (189), Expect = 3e-14
Identities = 51/155 (32%), Positives = 68/155 (43%), Gaps = 18/155 (11%)
Query: 202 CRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECRE----GGMVCRNGRCRNTVGSFR 256
C E G++LC C GF+ + C N C GG C G ++
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGK---NYT 327
Query: 257 CECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG---R 313
C C GY L + +C DVDEC + PC ++ C NT GG+ C C G++ G
Sbjct: 328 CRCPQGYQLDSSQLDCVDVDECQD--SPCAQE----CVNTPGGFRCECWVGYEPGGPGEG 381
Query: 314 RCVDRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
C D DEC CA G C N +G + C C G+
Sbjct: 382 ACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGY 415
Score = 69.7 bits (163), Expect = 4e-11
Identities = 38/99 (38%), Positives = 48/99 (48%), Gaps = 6/99 (6%)
Query: 761 GRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCH-NTDG-SYDCLCRTGYELDEDG 816
G F C C PG+R ++ CA + C+ P C G +Y C C GY+LD
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340
Query: 817 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
+C DVDEC+ C Q C NT G + C C GYE G
Sbjct: 341 LDCVDVDECQ--DSPCAQECVNTPGGFRCECWVGYEPGG 377
Score = 66.9 bits (156), Expect = 3e-10
Identities = 40/84 (47%), Positives = 44/84 (52%), Gaps = 12/84 (14%)
Query: 747 DVDECAAIPGLCAPG------RFRCVCGPGYRPAGE---VCADVDECAVRP--PPCDQLC 795
DVDECA CA G F C C GY AGE C DVDEC V P P CD LC
Sbjct: 385 DVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC-VGPGGPLCDSLC 443
Query: 796 HNTDGSYDCLCRTGYELDEDGANC 819
NT GS+ C C G+ L +G +C
Sbjct: 444 FNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 36.7 bits (81), Expect = 0.35
Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
Query: 791 CDQLC-HNTDGSYDCLCRTGYELDEDGANCRDVDECE----RDTHTCQQICSNTEGSYEC 845
C Q C DGS+ C CR G+ L +D C + C R TC + +Y C
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATC--VLGPHGKNYTC 328
Query: 846 SCEDGYE 852
C GY+
Sbjct: 329 RCPQGYQ 335
Score = 35.5 bits (78), Expect = 0.81
Identities = 24/81 (29%), Positives = 33/81 (40%), Gaps = 10/81 (12%)
Query: 561 CPHAC-ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CI-NTDG- 616
C C E GS++C C G+R D C N C C GG C+ G
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLL----DDLVTCASRNPCSSSP--CRGGATCVLGPHGK 324
Query: 617 SFLCDCDAGFEPSEDGTDCID 637
++ C C G++ DC+D
Sbjct: 325 NYTCRCPQGYQLDSSQLDCVD 345
>AB209895-1|BAD93132.1| 671|Homo sapiens complement component 1, q
subcomponent, receptor 1 variant protein.
Length = 671
Score = 143 bits (346), Expect = 3e-33
Identities = 80/191 (41%), Positives = 102/191 (53%), Gaps = 14/191 (7%)
Query: 90 FQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGA--FECRCPPGYRLTPSL 147
F CGC G+ + C + CS PCRG A CV P + CRCP GY+L S
Sbjct: 302 FLCGCRPGFRLLDDLVTCASRNPCS--SSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 359
Query: 148 DECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR---ENVCRDVDECSRPRPVCRN 204
+C DVDEC D +C NT G +RCEC GY E C+DVDEC+ R C
Sbjct: 360 LDCVDVDECQDSPCAQ--ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQ 417
Query: 205 GTCENLPGAYLCHCDDGFK-AGPNN-DCVDVNEC-REGGMVCRNGRCRNTVGSFRCECAP 261
G C N G++ C C++G+ AG + C DV+EC GG +C + C NT GSF C C P
Sbjct: 418 G-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC-DSLCFNTQGSFHCGCLP 475
Query: 262 GYTLTADGRNC 272
G+ L +G +C
Sbjct: 476 GWVLAPNGVSC 486
Score = 132 bits (319), Expect = 5e-30
Identities = 73/195 (37%), Positives = 93/195 (47%), Gaps = 12/195 (6%)
Query: 446 DGSFRCECPDGYVLAPDGLSCVDADECALDPRIC-GNGTCSNTRGG--YECQCSPGFTQG 502
DGSF C C G+ L D ++C + C+ P C G TC G Y C+C G+
Sbjct: 299 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLD 356
Query: 503 PDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVH-CRDIDECVQEPRV 560
Q CVDVDEC + + C C NT G FRC C GY G C+D+DEC
Sbjct: 357 SSQLDCVDVDECQD--SPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSP 414
Query: 561 CPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC 620
C C N GS+ C C EGY A +D C+D++EC +C NT GSF C
Sbjct: 415 CAQGCTNTDGSFHCSCEEGY--VLAGEDGTQ-CQDVDECVGPGGPLCDSLCFNTQGSFHC 471
Query: 621 DCDAGFEPSEDGTDC 635
C G+ + +G C
Sbjct: 472 GCLPGWVLAPNGVSC 486
Score = 127 bits (306), Expect = 2e-28
Identities = 77/190 (40%), Positives = 93/190 (48%), Gaps = 17/190 (8%)
Query: 402 CPAPDSAEFMRICQGGMGRPNLTQDLDECRVR----PDVCVGGR-CV-NTDG-SFRCECP 454
C F+ C+ G L DL C R C GG CV G ++ C CP
Sbjct: 294 CFEGGDGSFLCGCRPGF---RLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCP 350
Query: 455 DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG-PDQ-TCVDVDE 512
GY L L CVD DEC P C C NT GG+ C+C G+ G P + C DVDE
Sbjct: 351 QGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDE 407
Query: 513 CAEGRASCTFRCHNTAGSFRCTCPYGYAVAA-DGVHCRDIDECV-QEPRVCPHACENVVG 570
CA GR+ C C NT GSF C+C GY +A DG C+D+DECV +C C N G
Sbjct: 408 CALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQG 467
Query: 571 SYICKCPEGY 580
S+ C C G+
Sbjct: 468 SFHCGCLPGW 477
Score = 121 bits (292), Expect = 1e-26
Identities = 73/189 (38%), Positives = 89/189 (47%), Gaps = 18/189 (9%)
Query: 131 GAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIG----SYRCECKPGYTLRE 186
G+F C C PG+RL L C + C C G +G +Y C C GY L
Sbjct: 300 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP-C-RGGATCVLGPHGKNYTCRCPQGYQLDS 357
Query: 187 NV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND--CVDVNECREGGMV 242
+ C DVDEC + P + C N PG + C C G++ G + C DV+EC G
Sbjct: 358 SQLDCVDVDEC-QDSPCAQE--CVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSP 414
Query: 243 CRNGRCRNTVGSFRCECAPGYTLTA-DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
C G C NT GSF C C GY L DG C+DVDEC P G + C NT G +
Sbjct: 415 CAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC---VGPGGPLCDSLCFNTQGSFH 470
Query: 302 CSCGAGWKL 310
C C GW L
Sbjct: 471 CGCLPGWVL 479
Score = 120 bits (290), Expect = 2e-26
Identities = 75/205 (36%), Positives = 95/205 (46%), Gaps = 20/205 (9%)
Query: 164 HGDC-RNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNG-TCENLPGA--YLCH 217
H DC GS+ C C+PG+ L +++ C + CS CR G TC P Y C
Sbjct: 291 HQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCR 348
Query: 218 CDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRN-CRDV 275
C G++ + DCVDV+EC++ C C NT G FRCEC GY G C+DV
Sbjct: 349 CPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDV 405
Query: 276 DECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR---RCVDRDECKELPYVCAGGE 332
DEC PC + CTNT+G + CSC G+ L G +C D DEC
Sbjct: 406 DECALGRSPCAQ----GCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSL 461
Query: 333 CRNFNGGYVCECPAGWRFDKTAAVC 357
C N G + C C GW C
Sbjct: 462 CFNTQGSFHCGCLPGWVLAPNGVSC 486
Score = 110 bits (264), Expect = 2e-23
Identities = 56/114 (49%), Positives = 63/114 (55%), Gaps = 9/114 (7%)
Query: 747 DVDECAAIPGL--CA--PGRFRCVCGPGYRPAGE---VCADVDECAVRPPPCDQLCHNTD 799
DVDEC P C PG FRC C GY P G C DVDECA+ PC Q C NTD
Sbjct: 364 DVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTD 423
Query: 800 GSYDCLCRTGYEL-DEDGANCRDVDECERDTHT-CQQICSNTEGSYECSCEDGY 851
GS+ C C GY L EDG C+DVDEC C +C NT+GS+ C C G+
Sbjct: 424 GSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 477
Score = 99 bits (238), Expect = 3e-20
Identities = 73/214 (34%), Positives = 95/214 (44%), Gaps = 36/214 (16%)
Query: 297 NGGYECSCGAGWKLVGR--RCVDRDECKELPYVCAGGE-CRNFNGG--YVCECPAGWRFD 351
+G + C C G++L+ C R+ C P C GG C G Y C CP G++ D
Sbjct: 299 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLD 356
Query: 352 KTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFM 411
+ CVD DE + C + EC + G G CE C ++
Sbjct: 357 SSQLDCVD------VDECQDSPCAQ---------ECVNTPG---GFRCE-C-------WV 390
Query: 412 RICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLA-PDGLSCVDAD 470
GG G QD+DEC + C G C NTDGSF C C +GYVLA DG C D D
Sbjct: 391 GYEPGGPGE-GACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVD 448
Query: 471 ECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD 504
EC + C NT+G + C C PG+ P+
Sbjct: 449 ECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPN 482
Score = 95.9 bits (228), Expect = 5e-19
Identities = 63/168 (37%), Positives = 79/168 (47%), Gaps = 14/168 (8%)
Query: 24 CCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTC 83
C S GA C P G +T C + G ++ + +DEC P C C
Sbjct: 325 CSSSPCRGGATC-VLGPHGKN-YTCRCPQ--GYQLDSSQLDCVDVDECQDSP--CAQ-EC 377
Query: 84 HDTPTGFQCGCDHGYEHDNTSH-LCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
+TP GF+C C GYE C+DVDEC+ GR PC C N G+F C C GY
Sbjct: 378 VNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPC--AQGCTNTDGSFHCSCEEGYV 435
Query: 143 LT-PSLDECEDVDEC--GDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
L +C+DVDEC +CD C NT GS+ C C PG+ L N
Sbjct: 436 LAGEDGTQCQDVDECVGPGGPLCD-SLCFNTQGSFHCGCLPGWVLAPN 482
Score = 89.8 bits (213), Expect = 4e-17
Identities = 43/97 (44%), Positives = 56/97 (57%), Gaps = 5/97 (5%)
Query: 763 FRCVCGPGYR-PAGEV-CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN-C 819
+ C C GY+ + ++ C DVDEC + PC Q C NT G + C C GYE G C
Sbjct: 345 YTCRCPQGYQLDSSQLDCVDVDEC--QDSPCAQECVNTPGGFRCECWVGYEPGGPGEGAC 402
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
+DVDEC C Q C+NT+GS+ CSCE+GY G+
Sbjct: 403 QDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGE 439
Score = 84.6 bits (200), Expect = 1e-15
Identities = 74/218 (33%), Positives = 94/218 (43%), Gaps = 35/218 (16%)
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG-GYECSCGAGWKLV 311
GSF C C PG+ L D C + C PC R G +G Y C C G++L
Sbjct: 300 GSFLCGCRPGFRLLDDLVTCASRNPCSS--SPC-RGGATCVLGPHGKNYTCRCPQGYQLD 356
Query: 312 GRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTA-AVCVDERKELCYDE 368
+ CVD DEC++ P CA EC N GG+ CEC G+ C D DE
Sbjct: 357 SSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQD------VDE 407
Query: 369 WEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLD 428
GR A+ C ++G+ +C S E + G G QD+D
Sbjct: 408 CALGRSPCAQG-------CTNTDGSF---HC-------SCEEGYVLAGEDGTQ--CQDVD 448
Query: 429 ECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
EC C NT GSF C C G+VLAP+G+SC
Sbjct: 449 ECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 486
Score = 80.2 bits (189), Expect = 3e-14
Identities = 51/155 (32%), Positives = 68/155 (43%), Gaps = 18/155 (11%)
Query: 202 CRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECRE----GGMVCRNGRCRNTVGSFR 256
C E G++LC C GF+ + C N C GG C G ++
Sbjct: 290 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGK---NYT 346
Query: 257 CECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG---R 313
C C GY L + +C DVDEC + PC ++ C NT GG+ C C G++ G
Sbjct: 347 CRCPQGYQLDSSQLDCVDVDECQD--SPCAQE----CVNTPGGFRCECWVGYEPGGPGEG 400
Query: 314 RCVDRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
C D DEC CA G C N +G + C C G+
Sbjct: 401 ACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGY 434
Score = 69.7 bits (163), Expect = 4e-11
Identities = 38/99 (38%), Positives = 48/99 (48%), Gaps = 6/99 (6%)
Query: 761 GRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCH-NTDG-SYDCLCRTGYELDEDG 816
G F C C PG+R ++ CA + C+ P C G +Y C C GY+LD
Sbjct: 300 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 359
Query: 817 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
+C DVDEC+ C Q C NT G + C C GYE G
Sbjct: 360 LDCVDVDECQ--DSPCAQECVNTPGGFRCECWVGYEPGG 396
Score = 66.9 bits (156), Expect = 3e-10
Identities = 40/84 (47%), Positives = 44/84 (52%), Gaps = 12/84 (14%)
Query: 747 DVDECAAIPGLCAPG------RFRCVCGPGYRPAGE---VCADVDECAVRP--PPCDQLC 795
DVDECA CA G F C C GY AGE C DVDEC V P P CD LC
Sbjct: 404 DVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC-VGPGGPLCDSLC 462
Query: 796 HNTDGSYDCLCRTGYELDEDGANC 819
NT GS+ C C G+ L +G +C
Sbjct: 463 FNTQGSFHCGCLPGWVLAPNGVSC 486
Score = 36.7 bits (81), Expect = 0.35
Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
Query: 791 CDQLC-HNTDGSYDCLCRTGYELDEDGANCRDVDECE----RDTHTCQQICSNTEGSYEC 845
C Q C DGS+ C CR G+ L +D C + C R TC + +Y C
Sbjct: 290 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATC--VLGPHGKNYTC 347
Query: 846 SCEDGYE 852
C GY+
Sbjct: 348 RCPQGYQ 354
Score = 35.5 bits (78), Expect = 0.81
Identities = 24/81 (29%), Positives = 33/81 (40%), Gaps = 10/81 (12%)
Query: 561 CPHAC-ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-CI-NTDG- 616
C C E GS++C C G+R D C N C C GG C+ G
Sbjct: 290 CHQDCFEGGDGSFLCGCRPGFRLL----DDLVTCASRNPCSSSP--CRGGATCVLGPHGK 343
Query: 617 SFLCDCDAGFEPSEDGTDCID 637
++ C C G++ DC+D
Sbjct: 344 NYTCRCPQGYQLDSSQLDCVD 364
>AJ295142-1|CAC82720.1| 652|Homo sapiens C1q receptor protein
protein.
Length = 652
Score = 141 bits (342), Expect = 8e-33
Identities = 79/191 (41%), Positives = 101/191 (52%), Gaps = 14/191 (7%)
Query: 90 FQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGA--FECRCPPGYRLTPSL 147
F CGC G+ + C + CS PCRG A C P + CRCP GY+L S
Sbjct: 283 FLCGCRPGFRLLDDLVTCASRNPCS--SSPCRGGATCALGPHGKNYTCRCPQGYQLDSSQ 340
Query: 148 DECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR---ENVCRDVDECSRPRPVCRN 204
+C DVDEC D +C NT G +RCEC GY E C+DVDEC+ R C
Sbjct: 341 LDCVDVDECQDSPCAQ--ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQ 398
Query: 205 GTCENLPGAYLCHCDDGFK-AGPNN-DCVDVNEC-REGGMVCRNGRCRNTVGSFRCECAP 261
G C N G++ C C++G+ AG + C DV+EC GG +C + C NT GSF C C P
Sbjct: 399 G-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC-DSLCFNTQGSFHCGCLP 456
Query: 262 GYTLTADGRNC 272
G+ L +G +C
Sbjct: 457 GWVLAPNGVSC 467
Score = 133 bits (322), Expect = 2e-30
Identities = 73/195 (37%), Positives = 94/195 (48%), Gaps = 12/195 (6%)
Query: 446 DGSFRCECPDGYVLAPDGLSCVDADECALDPRIC-GNGTCSNTRGG--YECQCSPGFTQG 502
DGSF C C G+ L D ++C + C+ P C G TC+ G Y C+C G+
Sbjct: 280 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCALGPHGKNYTCRCPQGYQLD 337
Query: 503 PDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVH-CRDIDECVQEPRV 560
Q CVDVDEC + + C C NT G FRC C GY G C+D+DEC
Sbjct: 338 SSQLDCVDVDECQD--SPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSP 395
Query: 561 CPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC 620
C C N GS+ C C EGY A +D C+D++EC +C NT GSF C
Sbjct: 396 CAQGCTNTDGSFHCSCEEGY--VLAGEDGTQ-CQDVDECVGPGGPLCDSLCFNTQGSFHC 452
Query: 621 DCDAGFEPSEDGTDC 635
C G+ + +G C
Sbjct: 453 GCLPGWVLAPNGVSC 467
Score = 122 bits (293), Expect = 7e-27
Identities = 72/187 (38%), Positives = 87/187 (46%), Gaps = 14/187 (7%)
Query: 131 GAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCR-NTIG-SYRCECKPGYTLRENV 188
G+F C C PG+RL L C + C C G +Y C C GY L +
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCALGPHGKNYTCRCPQGYQLDSSQ 340
Query: 189 --CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND--CVDVNECREGGMVCR 244
C DVDEC + P + C N PG + C C G++ G + C DV+EC G C
Sbjct: 341 LDCVDVDEC-QDSPCAQE--CVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCA 397
Query: 245 NGRCRNTVGSFRCECAPGYTLTA-DGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECS 303
G C NT GSF C C GY L DG C+DVDEC P G + C NT G + C
Sbjct: 398 QG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC---VGPGGPLCDSLCFNTQGSFHCG 453
Query: 304 CGAGWKL 310
C GW L
Sbjct: 454 CLPGWVL 460
Score = 121 bits (291), Expect = 1e-26
Identities = 75/205 (36%), Positives = 95/205 (46%), Gaps = 20/205 (9%)
Query: 164 HGDC-RNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNG-TCENLPGA--YLCH 217
H DC GS+ C C+PG+ L +++ C + CS CR G TC P Y C
Sbjct: 272 HQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCALGPHGKNYTCR 329
Query: 218 CDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRN-CRDV 275
C G++ + DCVDV+EC++ C C NT G FRCEC GY G C+DV
Sbjct: 330 CPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDV 386
Query: 276 DECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR---RCVDRDECKELPYVCAGGE 332
DEC PC + CTNT+G + CSC G+ L G +C D DEC
Sbjct: 387 DECALGRSPCAQ----GCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSL 442
Query: 333 CRNFNGGYVCECPAGWRFDKTAAVC 357
C N G + C C GW C
Sbjct: 443 CFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 110 bits (264), Expect = 2e-23
Identities = 56/114 (49%), Positives = 63/114 (55%), Gaps = 9/114 (7%)
Query: 747 DVDECAAIPGL--CA--PGRFRCVCGPGYRPAGE---VCADVDECAVRPPPCDQLCHNTD 799
DVDEC P C PG FRC C GY P G C DVDECA+ PC Q C NTD
Sbjct: 345 DVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTD 404
Query: 800 GSYDCLCRTGYEL-DEDGANCRDVDECERDTHT-CQQICSNTEGSYECSCEDGY 851
GS+ C C GY L EDG C+DVDEC C +C NT+GS+ C C G+
Sbjct: 405 GSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 458
Score = 107 bits (256), Expect = 2e-22
Identities = 59/127 (46%), Positives = 68/127 (53%), Gaps = 8/127 (6%)
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVL-APDGLSCVDADECALDPRICGNGTC 484
D+DEC+ P C CVNT G FRCEC GY P +C D DECAL C G C
Sbjct: 345 DVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG-C 400
Query: 485 SNTRGGYECQCSPGFT-QGPDQT-CVDVDEC-AEGRASCTFRCHNTAGSFRCTCPYGYAV 541
+NT G + C C G+ G D T C DVDEC G C C NT GSF C C G+ +
Sbjct: 401 TNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVL 460
Query: 542 AADGVHC 548
A +GV C
Sbjct: 461 APNGVSC 467
Score = 100 bits (240), Expect = 2e-20
Identities = 73/214 (34%), Positives = 95/214 (44%), Gaps = 36/214 (16%)
Query: 297 NGGYECSCGAGWKLVGR--RCVDRDECKELPYVCAGGE-CRNFNGG--YVCECPAGWRFD 351
+G + C C G++L+ C R+ C P C GG C G Y C CP G++ D
Sbjct: 280 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCALGPHGKNYTCRCPQGYQLD 337
Query: 352 KTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFM 411
+ CVD DE + C + EC + G G CE C ++
Sbjct: 338 SSQLDCVD------VDECQDSPCAQ---------ECVNTPG---GFRCE-C-------WV 371
Query: 412 RICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLA-PDGLSCVDAD 470
GG G QD+DEC + C G C NTDGSF C C +GYVLA DG C D D
Sbjct: 372 GYEPGGPGE-GACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVD 429
Query: 471 ECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD 504
EC + C NT+G + C C PG+ P+
Sbjct: 430 ECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPN 463
Score = 97.5 bits (232), Expect = 2e-19
Identities = 64/168 (38%), Positives = 80/168 (47%), Gaps = 14/168 (8%)
Query: 24 CCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTC 83
C S GA C A P G +T C + G ++ + +DEC P C C
Sbjct: 306 CSSSPCRGGATC-ALGPHGKN-YTCRCPQ--GYQLDSSQLDCVDVDECQDSP--CAQ-EC 358
Query: 84 HDTPTGFQCGCDHGYEHDNTSH-LCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
+TP GF+C C GYE C+DVDEC+ GR PC C N G+F C C GY
Sbjct: 359 VNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPC--AQGCTNTDGSFHCSCEEGYV 416
Query: 143 LT-PSLDECEDVDEC--GDQRICDHGDCRNTIGSYRCECKPGYTLREN 187
L +C+DVDEC +CD C NT GS+ C C PG+ L N
Sbjct: 417 LAGEDGTQCQDVDECVGPGGPLCD-SLCFNTQGSFHCGCLPGWVLAPN 463
Score = 89.8 bits (213), Expect = 4e-17
Identities = 43/97 (44%), Positives = 56/97 (57%), Gaps = 5/97 (5%)
Query: 763 FRCVCGPGYR-PAGEV-CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN-C 819
+ C C GY+ + ++ C DVDEC + PC Q C NT G + C C GYE G C
Sbjct: 326 YTCRCPQGYQLDSSQLDCVDVDEC--QDSPCAQECVNTPGGFRCECWVGYEPGGPGEGAC 383
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
+DVDEC C Q C+NT+GS+ CSCE+GY G+
Sbjct: 384 QDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGE 420
Score = 85.0 bits (201), Expect = 1e-15
Identities = 74/218 (33%), Positives = 94/218 (43%), Gaps = 35/218 (16%)
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNG-GYECSCGAGWKLV 311
GSF C C PG+ L D C + C PC R G +G Y C C G++L
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSS--SPC-RGGATCALGPHGKNYTCRCPQGYQLD 337
Query: 312 GRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTA-AVCVDERKELCYDE 368
+ CVD DEC++ P CA EC N GG+ CEC G+ C D DE
Sbjct: 338 SSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQD------VDE 388
Query: 369 WEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLD 428
GR A+ C ++G+ +C S E + G G QD+D
Sbjct: 389 CALGRSPCAQG-------CTNTDGSF---HC-------SCEEGYVLAGEDGTQ--CQDVD 429
Query: 429 ECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
EC C NT GSF C C G+VLAP+G+SC
Sbjct: 430 ECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 81.0 bits (191), Expect = 2e-14
Identities = 51/155 (32%), Positives = 68/155 (43%), Gaps = 18/155 (11%)
Query: 202 CRNGTCENLPGAYLCHCDDGFKAGPNN-DCVDVNECRE----GGMVCRNGRCRNTVGSFR 256
C E G++LC C GF+ + C N C GG C G ++
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCALGPHGK---NYT 327
Query: 257 CECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG---R 313
C C GY L + +C DVDEC + PC ++ C NT GG+ C C G++ G
Sbjct: 328 CRCPQGYQLDSSQLDCVDVDECQD--SPCAQE----CVNTPGGFRCECWVGYEPGGPGEG 381
Query: 314 RCVDRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
C D DEC CA G C N +G + C C G+
Sbjct: 382 ACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGY 415
Score = 70.1 bits (164), Expect = 3e-11
Identities = 38/99 (38%), Positives = 48/99 (48%), Gaps = 6/99 (6%)
Query: 761 GRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCH-NTDG-SYDCLCRTGYELDEDG 816
G F C C PG+R ++ CA + C+ P C G +Y C C GY+LD
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCALGPHGKNYTCRCPQGYQLDSSQ 340
Query: 817 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG 855
+C DVDEC+ C Q C NT G + C C GYE G
Sbjct: 341 LDCVDVDECQ--DSPCAQECVNTPGGFRCECWVGYEPGG 377
Score = 66.9 bits (156), Expect = 3e-10
Identities = 40/84 (47%), Positives = 44/84 (52%), Gaps = 12/84 (14%)
Query: 747 DVDECAAIPGLCAPG------RFRCVCGPGYRPAGE---VCADVDECAVRP--PPCDQLC 795
DVDECA CA G F C C GY AGE C DVDEC V P P CD LC
Sbjct: 385 DVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC-VGPGGPLCDSLC 443
Query: 796 HNTDGSYDCLCRTGYELDEDGANC 819
NT GS+ C C G+ L +G +C
Sbjct: 444 FNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 37.5 bits (83), Expect = 0.20
Identities = 21/65 (32%), Positives = 28/65 (43%), Gaps = 3/65 (4%)
Query: 791 CDQLC-HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICS-NTEG-SYECSC 847
C Q C DGS+ C CR G+ L +D C + C C+ G +Y C C
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCALGPHGKNYTCRC 330
Query: 848 EDGYE 852
GY+
Sbjct: 331 PQGYQ 335
Score = 35.1 bits (77), Expect = 1.1
Identities = 23/81 (28%), Positives = 32/81 (39%), Gaps = 10/81 (12%)
Query: 561 CPHAC-ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV--CINTDG- 616
C C E GS++C C G+R D C N C C GG + G
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLL----DDLVTCASRNPCSSSP--CRGGATCALGPHGK 324
Query: 617 SFLCDCDAGFEPSEDGTDCID 637
++ C C G++ DC+D
Sbjct: 325 NYTCRCPQGYQLDSSQLDCVD 345
>AC005327-1|AAC27673.1| 287|Homo sapiens CD97_HUMAN, partial CDS
protein.
Length = 287
Score = 140 bits (338), Expect = 3e-32
Identities = 84/211 (39%), Positives = 103/211 (48%), Gaps = 34/211 (16%)
Query: 120 CRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHG---DCRNTIGSYRC 176
C + CVN A CRC PG+ + D++EC G DC NT GSY C
Sbjct: 30 CPQDSSCVN---ATACRCNPGFSSFSEIITTPDINECATLSKVSCGKFSDCWNTEGSYDC 86
Query: 177 ECKPGY-------TLR---ENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAG 225
C PGY T + EN C+DVDEC + +C++ GTC N G+Y C C GFK
Sbjct: 87 VCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK-- 144
Query: 226 PNNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTL---TADGRN---CRDVDEC 278
DVNEC G C + C N VGS++C C PG+ + +G N C DVDEC
Sbjct: 145 ------DVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDEC 198
Query: 279 DELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
H C D + C NT G Y C C GWK
Sbjct: 199 SSGQHQC--DSSTVCFNTVGSYSCRCRPGWK 227
Score = 115 bits (276), Expect = 8e-25
Identities = 70/205 (34%), Positives = 96/205 (46%), Gaps = 30/205 (14%)
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRI-CGN-GTCSNTRGGYECQCSPG- 498
CVN C C G+ + ++ D +ECA ++ CG C NT G Y+C CSPG
Sbjct: 36 CVNATA---CRCNPGFSSFSEIITTPDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGY 92
Query: 499 --------FTQGPDQTCVDVDECAEGRASCTF--RCHNTAGSFRCTCPYGYAVAADGVHC 548
F + TC DVDEC + C C NT GS+ C C G+
Sbjct: 93 EPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGF--------- 143
Query: 549 RDIDECVQEPRVCPHA--CENVVGSYICKCPEGYRRTSAPQDSEN--ACEDINECEEQED 604
+D++EC C + C N VGSY C+C G++ + N CED++EC +
Sbjct: 144 KDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQH 203
Query: 605 LC-SGGVCINTDGSFLCDCDAGFEP 628
C S VC NT GS+ C C G++P
Sbjct: 204 QCDSSTVCFNTVGSYSCRCRPGWKP 228
Score = 114 bits (275), Expect = 1e-24
Identities = 77/229 (33%), Positives = 102/229 (44%), Gaps = 37/229 (16%)
Query: 397 RYCER-CPAPDSAEFMRICQGGMGRPNL-----TQDLDECRVRPDVCVG--GRCVNTDGS 448
R C R CP S C+ G + T D++EC V G C NT+GS
Sbjct: 24 RGCARWCPQDSSCVNATACRCNPGFSSFSEIITTPDINECATLSKVSCGKFSDCWNTEGS 83
Query: 449 FRCECPDGYVLAPDGLS--------CVDADECALDPRICGN-GTCSNTRGGYECQCSPGF 499
+ C C GY + C D DEC +PR+C + GTC NT G Y CQC PGF
Sbjct: 84 YDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGF 143
Query: 500 TQGPDQTCVDVDECAEGRASC--TFRCHNTAGSFRCTCPYGYAV------AADGVHCRDI 551
DV+EC G+ C + C N GS++C C G+ + C D+
Sbjct: 144 K--------DVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDV 195
Query: 552 DECVQEPRVCPHA--CENVVGSYICKCPEGYR-RTSAPQD-SENACEDI 596
DEC C + C N VGSY C+C G++ R P + + CED+
Sbjct: 196 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDM 244
Score = 107 bits (257), Expect = 2e-22
Identities = 69/227 (30%), Positives = 100/227 (44%), Gaps = 36/227 (15%)
Query: 146 SLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR--DVDECSRPRPV-C 202
+L E D G R C + + + C C PG++ + D++EC+ V C
Sbjct: 14 TLPGAETQDSRGCARWCPQDS--SCVNATACRCNPGFSSFSEIITTPDINECATLSKVSC 71
Query: 203 -RNGTCENLPGAYLCHCDDG---------FKAGPNNDCVDVNECREGGMVCRN-GRCRNT 251
+ C N G+Y C C G FK N C DV+EC++ +C++ G C NT
Sbjct: 72 GKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNT 131
Query: 252 VGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
+GS+ C+C PG+ +DV+EC +PC + C N G Y+C C GW+ +
Sbjct: 132 LGSYTCQCLPGF---------KDVNECTSGQNPC--HSSTHCLNNVGSYQCRCRPGWQPI 180
Query: 312 --------GRRCVDRDECKELPYVCAGGE-CRNFNGGYVCECPAGWR 349
C D DEC + C C N G Y C C GW+
Sbjct: 181 PGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 227
Score = 106 bits (254), Expect = 4e-22
Identities = 70/215 (32%), Positives = 96/215 (44%), Gaps = 33/215 (15%)
Query: 38 CPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQL-C-KPGTCHDTPTGFQCGCD 95
CP S + C PG T I+EC + ++ C K C +T + C C
Sbjct: 30 CPQDSSCVNATACRCNPGFSSFSEIITTPDINECATLSKVSCGKFSDCWNTEGSYDCVCS 89
Query: 96 HGYE--------HDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSL 147
GYE + + + C+DVDEC C+ CVN G++ C+C PG++
Sbjct: 90 PGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK----- 144
Query: 148 DECEDVDEC-GDQRICDHG-DCRNTIGSYRCECKPGYT--------LRENVCRDVDECSR 197
DV+EC Q C C N +GSY+C C+PG+ VC DVDECS
Sbjct: 145 ----DVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSS 200
Query: 198 PRPVCRNGT-CENLPGAYLCHCDDGFKAG---PNN 228
+ C + T C N G+Y C C G+K PNN
Sbjct: 201 GQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNN 235
Score = 79.4 bits (187), Expect = 5e-14
Identities = 48/126 (38%), Positives = 58/126 (46%), Gaps = 25/126 (19%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCH-- 796
DVDEC P LC G + C C PG++ DV+EC PC H
Sbjct: 111 DVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK-------DVNECTSGQNPCHSSTHCL 163
Query: 797 NTDGSYDCLCRTGYEL---DEDGAN---CRDVDECERDTHTCQQ--ICSNTEGSYECSCE 848
N GSY C CR G++ +G N C DVDEC H C +C NT GSY C C
Sbjct: 164 NNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCR 223
Query: 849 DGYEKR 854
G++ R
Sbjct: 224 PGWKPR 229
Score = 75.4 bits (177), Expect = 8e-13
Identities = 40/111 (36%), Positives = 57/111 (51%), Gaps = 15/111 (13%)
Query: 765 CVCGPGYRPAGEVCA--DVDECA-VRPPPCDQL--CHNTDGSYDCLCRTGYE-------- 811
C C PG+ E+ D++ECA + C + C NT+GSYDC+C GYE
Sbjct: 42 CRCNPGFSSFSEIITTPDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTF 101
Query: 812 LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVG 860
+E C+DVDEC+++ C+ C NT GSY C C G++ + G
Sbjct: 102 KNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKDVNECTSG 152
Score = 75.4 bits (177), Expect = 8e-13
Identities = 40/109 (36%), Positives = 58/109 (53%), Gaps = 8/109 (7%)
Query: 533 CTCPYGYAVAADGVHCRDIDECVQEPRV-CPHA--CENVVGSYICKCPEGYRRTSAPQ-- 587
C C G++ ++ + DI+EC +V C C N GSY C C GY S +
Sbjct: 42 CRCNPGFSSFSEIITTPDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTF 101
Query: 588 --DSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFEPSEDGT 633
+SEN C+D++EC++ LC S G C+NT GS+ C C GF+ + T
Sbjct: 102 KNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKDVNECT 150
Score = 66.1 bits (154), Expect = 5e-10
Identities = 38/106 (35%), Positives = 46/106 (43%), Gaps = 23/106 (21%)
Query: 761 GRFRCVCGPGYRPAG----------EVCADVDECAVRPPPCDQ--LCHNTDGSYDCLCRT 808
G + CVC PGY P C DVDEC P C C NT GSY C C
Sbjct: 82 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 141
Query: 809 GYELDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE 852
G+ +DV+EC + C C N GSY+C C G++
Sbjct: 142 GF---------KDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 178
Score = 65.7 bits (153), Expect = 7e-10
Identities = 66/247 (26%), Positives = 90/247 (36%), Gaps = 45/247 (18%)
Query: 265 LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCV--DRDECK 322
LT G +D C C +D SC N C C G+ D +EC
Sbjct: 13 LTLPGAETQDSRGCARW---CPQDS--SCVNATA---CRCNPGFSSFSEIITTPDINECA 64
Query: 323 ELPYVCAG--GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPL 380
L V G +C N G Y C C G+ A +E + C D C +
Sbjct: 65 TLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQD---VDECQQ---- 117
Query: 381 QLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGG 440
P C S G C + + C G +D++EC + C
Sbjct: 118 ---NPRLCKSYGT-----CVNTLGSYTCQ----CLPGF------KDVNECTSGQNPCHSS 159
Query: 441 -RCVNTDGSFRCECPDGY------VLAPDGLSCVDADECALDPRICGNGT-CSNTRGGYE 492
C+N GS++C C G+ P+ C D DEC+ C + T C NT G Y
Sbjct: 160 THCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYS 219
Query: 493 CQCSPGF 499
C+C PG+
Sbjct: 220 CRCRPGW 226
Score = 40.3 bits (90), Expect = 0.028
Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 9/93 (9%)
Query: 556 QEPRVCPHAC---ENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-- 610
Q+ R C C + V + C+C G+ S + DINEC + G
Sbjct: 21 QDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITTP----DINECATLSKVSCGKFSD 76
Query: 611 CINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
C NT+GS+ C C G+EP + TC
Sbjct: 77 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTC 109
Score = 34.3 bits (75), Expect = 1.9
Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 7/73 (9%)
Query: 54 PGEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCD------HGYEHDNTSHL 106
PG P + +DEC C T C +T + C C HG ++ +
Sbjct: 181 PGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTV 240
Query: 107 CRDVDECSWGRPP 119
C D+ +W PP
Sbjct: 241 CEDMTFSTWTPPP 253
>AK027775-1|BAB55358.1| 537|Homo sapiens protein ( Homo sapiens
cDNA FLJ14869 fis, clone PLACE1002474, moderately
similar to Mus musculus matrilin-2 precursor mRNA. ).
Length = 537
Score = 139 bits (336), Expect = 4e-32
Identities = 69/197 (35%), Positives = 94/197 (47%), Gaps = 9/197 (4%)
Query: 448 SFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-QT 506
S+ C C GY L P+G +C D CA C C NT + CQCS GF D T
Sbjct: 4 SYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLMT 62
Query: 507 CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
C VD C C + C N SF C CP G+ + +DG C +D C C H+C
Sbjct: 63 CSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCV 122
Query: 567 NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
+ S++C+C EGY ++ C + C+ + C +C+N+D S+ C+C GF
Sbjct: 123 SSEDSFVCQCFEGY----ILREDGKTCRRKDVCQAIDHGCE-HICVNSDDSYTCECLEGF 177
Query: 627 EPSEDGTDCIDRRTGTC 643
+EDG C RR C
Sbjct: 178 RLAEDGKRC--RRKDVC 192
Score = 134 bits (324), Expect = 1e-30
Identities = 70/210 (33%), Positives = 99/210 (47%), Gaps = 8/210 (3%)
Query: 427 LDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSN 486
+D C + C C+NT+ SF C+C +G+++ D ++C D C L C +C N
Sbjct: 25 VDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLMTCSRVDYCLLSDHGC-EYSCVN 82
Query: 487 TRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADG 545
+ CQC G D +TC +D CA G C C ++ SF C C GY + DG
Sbjct: 83 MDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDG 142
Query: 546 VHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDL 605
CR D C C H C N SY C+C EG+R +D + C + C+
Sbjct: 143 KTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLA---EDGKR-CRRKDVCKSTHHG 198
Query: 606 CSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
C +C+N S++C C GF +EDG C
Sbjct: 199 CEH-ICVNNGNSYICKCSEGFVLAEDGRRC 227
Score = 132 bits (319), Expect = 5e-30
Identities = 73/225 (32%), Positives = 105/225 (46%), Gaps = 18/225 (8%)
Query: 132 AFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD---CRNTIGSYRCECKPGYTLRENV 188
++ CRC GY L P+ C VD C Q DHG C NT S+ C+C G+ + E++
Sbjct: 4 SYYCRCHRGYTLDPNGKTCSRVDHCAQQ---DHGCEQLCLNTEDSFVCQCSEGFLINEDL 60
Query: 189 --CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMVCRN 245
C VD C C +C N+ ++ C C +G C ++ C G C +
Sbjct: 61 MTCSRVDYCLLSDHGCEY-SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH 119
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C ++ SF C+C GY L DG+ CR D C + H C C N++ Y C C
Sbjct: 120 S-CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGC----EHICVNSDDSYTCECL 174
Query: 306 AGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
G++L G+RC +D CK + C C N Y+C+C G+
Sbjct: 175 EGFRLAEDGKRCRRKDVCKSTHHGCE-HICVNNGNSYICKCSEGF 218
Score = 123 bits (297), Expect = 2e-27
Identities = 74/216 (34%), Positives = 97/216 (44%), Gaps = 13/216 (6%)
Query: 373 RCHRARPLQLARPECCCSEGAAWGRY-CERCPAPDSAEFMRICQGGMGRPNLTQDLDECR 431
RCHR L C + A + CE+ F+ C G + +DL C
Sbjct: 8 RCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGF---LINEDLMTCS 64
Query: 432 VRPDVCVGG------RCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
R D C+ CVN D SF C+CP+G+VL DG +C D CAL C + +C
Sbjct: 65 -RVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH-SCV 122
Query: 486 NTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAAD 544
++ + CQC G+ D +TC D C C C N+ S+ C C G+ +A D
Sbjct: 123 SSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAED 182
Query: 545 GVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGY 580
G CR D C C H C N SYICKC EG+
Sbjct: 183 GKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGF 218
Score = 120 bits (289), Expect = 2e-26
Identities = 73/244 (29%), Positives = 105/244 (43%), Gaps = 22/244 (9%)
Query: 90 FQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDE 149
+ C C GY D C VD C+ C + C+N +F C+C G+ + L
Sbjct: 5 YYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQL--CLNTEDSFVCQCSEGFLINEDLMT 62
Query: 150 CEDVDECGDQRICDHG---DCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPVCRN 204
C VD C + DHG C N S+ C+C G+ LR + C +D C+ C +
Sbjct: 63 CSRVDYC---LLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH 119
Query: 205 GTCENLPGAYLCHCDDGF-KAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGY 263
+C + +++C C +G+ C + C+ C + C N+ S+ CEC G+
Sbjct: 120 -SCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGF 177
Query: 264 TLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--GRRCVDRDEC 321
L DG+ CR D C H C C N Y C C G+ L GRRC +C
Sbjct: 178 RLAEDGKRCRRKDVCKSTHHGC----EHICVNNGNSYICKCSEGFVLAEDGRRC---KKC 230
Query: 322 KELP 325
E P
Sbjct: 231 TEGP 234
Score = 110 bits (265), Expect = 2e-23
Identities = 69/228 (30%), Positives = 99/228 (43%), Gaps = 12/228 (5%)
Query: 55 GEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS 114
G ++P +D C C+ C +T F C C G+ + C VD C
Sbjct: 12 GYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLMTCSRVDYCL 70
Query: 115 WGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDEC--GDQRICDHGDCRNTIG 172
C CVN+ +F C+CP G+ L C +D C GD C+H C ++
Sbjct: 71 LSDHGCE--YSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHG-CEHS-CVSSED 126
Query: 173 SYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK-AGPNND 229
S+ C+C GY LRE+ CR D C C + C N +Y C C +GF+ A
Sbjct: 127 SFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKR 185
Query: 230 CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE 277
C + C+ C + C N S+ C+C+ G+ L DGR C+ E
Sbjct: 186 CRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 232
Score = 110 bits (264), Expect = 2e-23
Identities = 73/238 (30%), Positives = 102/238 (42%), Gaps = 19/238 (7%)
Query: 173 SYRCECKPGYTLREN--VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPN-ND 229
SY C C GYTL N C VD C++ C C N +++C C +GF +
Sbjct: 4 SYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLMT 62
Query: 230 CVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDG 289
C V+ C C C N SF C+C G+ L +DG+ C +D C H C
Sbjct: 63 CSRVDYCLLSDHGCEYS-CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH-- 119
Query: 290 NPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
SC ++ + C C G+ L G+ C +D C+ + + C C N + Y CEC G
Sbjct: 120 --SCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEG 176
Query: 348 WRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEG---AAWGRYCERC 402
+R + C RK++C C C CSEG A GR C++C
Sbjct: 177 FRLAEDGKRC--RRKDVCKSTHHG--CEHICVNNGNSYICKCSEGFVLAEDGRRCKKC 230
Score = 85.8 bits (203), Expect = 6e-16
Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 2/96 (2%)
Query: 763 FRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
F C C G+ R G+ CA +D CA+ C+ C +++ S+ C C GY L EDG CR
Sbjct: 87 FACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCR 146
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
D C+ H C+ IC N++ SY C C +G+ D
Sbjct: 147 RKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAED 182
Score = 85.4 bits (202), Expect = 8e-16
Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 2/96 (2%)
Query: 763 FRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
+ C C GY P G+ C+ VD CA + C+QLC NT+ S+ C C G+ ++ED C
Sbjct: 5 YYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLMTCS 64
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
VD C H C+ C N + S+ C C +G+ R D
Sbjct: 65 RVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSD 100
Score = 85.0 bits (201), Expect = 1e-15
Identities = 37/91 (40%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Query: 763 FRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
F C C GY R G+ C D C C+ +C N+D SY C C G+ L EDG CR
Sbjct: 128 FVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCR 187
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
D C+ H C+ IC N SY C C +G+
Sbjct: 188 RKDVCKSTHHGCEHICVNNGNSYICKCSEGF 218
Score = 82.2 bits (194), Expect = 7e-15
Identities = 42/128 (32%), Positives = 58/128 (45%), Gaps = 3/128 (2%)
Query: 427 LDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSN 486
LD C + C CV+++ SF C+C +GY+L DG +C D C C + C N
Sbjct: 107 LDSCALGDHGCEHS-CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVN 164
Query: 487 TRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADG 545
+ Y C+C GF D + C D C C C N S+ C C G+ +A DG
Sbjct: 165 SDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDG 224
Query: 546 VHCRDIDE 553
C+ E
Sbjct: 225 RRCKKCTE 232
Score = 77.4 bits (182), Expect = 2e-13
Identities = 68/244 (27%), Positives = 93/244 (38%), Gaps = 33/244 (13%)
Query: 254 SFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG- 312
S+ C C GYTL +G+ C VD C + H C + C NT + C C G+ +
Sbjct: 4 SYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ----LCLNTEDSFVCQCSEGFLINED 59
Query: 313 -RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEA 371
C D C + C C N + + C+CP G C D
Sbjct: 60 LMTCSRVDYCLLSDHGCEYS-CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCE 118
Query: 372 GRCHRARPLQLARPECCCSEGAAW---GRYCER---CPAPD--------SAEFMRICQGG 417
C + + C C EG G+ C R C A D +++ C+
Sbjct: 119 HSCVSSEDSFV----CQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECL 174
Query: 418 MGRPNLTQDLDECRVRPDVCVGGR------CVNTDGSFRCECPDGYVLAPDGLSCVDADE 471
G L +D CR R DVC CVN S+ C+C +G+VLA DG C E
Sbjct: 175 EGF-RLAEDGKRCR-RKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 232
Query: 472 CALD 475
+D
Sbjct: 233 GPID 236
Score = 73.3 bits (172), Expect = 3e-12
Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Query: 763 FRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
F C C G+ ++ C+ VD C + C+ C N D S+ C C G+ L DG C
Sbjct: 46 FVCQCSEGFLINEDLMTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCA 105
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
+D C H C+ C ++E S+ C C +GY R D
Sbjct: 106 KLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRED 141
Score = 66.1 bits (154), Expect = 5e-10
Identities = 24/51 (47%), Positives = 31/51 (60%)
Query: 801 SYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
SY C C GY LD +G C VD C + H C+Q+C NTE S+ C C +G+
Sbjct: 4 SYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGF 54
Score = 48.4 bits (110), Expect = 1e-04
Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Query: 763 FRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
+ C C G+R A G+ C D C C+ +C N SY C C G+ L EDG C+
Sbjct: 169 YTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCK 228
Query: 821 DVDE 824
E
Sbjct: 229 KCTE 232
>U57523-1|AAB06946.1| 446|Homo sapiens protein ( Human nel homolog
mRNA, partial cds. ).
Length = 446
Score = 136 bits (330), Expect = 2e-31
Identities = 81/212 (38%), Positives = 101/212 (47%), Gaps = 21/212 (9%)
Query: 104 SHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGD-QRIC 162
S C D+DEC+ C CVNLPG + C C PGY C + DECG Q C
Sbjct: 47 SAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDF-SCTEHDECGSGQHNC 105
Query: 163 D-HGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDD 220
D + C NT+ + C CKPGY +CR E CR GTC P C C
Sbjct: 106 DENAICTNTVQGHSCTCKPGYVGNGTICRAFCE-----EGCRYGGTCV-APNK--CVCPS 157
Query: 221 GFKAGPNNDCVDVNECREGGMVCRN-GRCRNTVGSFRCECAPGY----TLTADGRNCRDV 275
GF G + + D++EC EG + C N RC N G CEC G+ T + G +C D+
Sbjct: 158 GF-TGSHCE-KDIDECSEGIIECHNHSRCVNLPGWHHCECRSGFHDDGTYSLSGESCIDI 215
Query: 276 DECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
DEC H C D +C N GG++C C G
Sbjct: 216 DECALRTHTCWNDS--ACINLAGGFDCLCPCG 245
Score = 118 bits (283), Expect = 1e-25
Identities = 76/217 (35%), Positives = 101/217 (46%), Gaps = 21/217 (9%)
Query: 425 QDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICG-NG 482
+D+DEC + C CVN G +RC+C GY+ D SC + DEC C N
Sbjct: 51 EDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRV-DDFSCTEHDECGSGQHNCDENA 109
Query: 483 TCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVA 542
C+NT G+ C C PG+ G C C EG C + A + +C CP G+
Sbjct: 110 ICTNTVQGHSCTCKPGYV-GNGTICRAF--CEEG---CRYGGTCVAPN-KCVCPSGFT-- 160
Query: 543 ADGVHC-RDIDECVQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENACEDINEC 599
G HC +DIDEC + C + C N+ G + C+C G+ S +C DI+EC
Sbjct: 161 --GSHCEKDIDECSEGIIECHNHSRCVNLPGWHHCECRSGFHDDGTYSLSGESCIDIDEC 218
Query: 600 EEQEDLC-SGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
+ C + CIN G F C C G PS G DC
Sbjct: 219 ALRTHTCWNDSACINLAGGFDCLCPCG--PSCSG-DC 252
Score = 107 bits (257), Expect = 2e-22
Identities = 71/210 (33%), Positives = 93/210 (44%), Gaps = 26/210 (12%)
Query: 150 CEDVDECGDQRICDHGD--CRNTIGSYRCECKPGYTLRENV-CRDVDECSRPRPVC-RNG 205
CED+DEC + H + C N G YRC+C PGY ++ C + DEC + C N
Sbjct: 50 CEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENA 109
Query: 206 TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTL 265
C N + C C G+ G C C EG CR G V +C C G+T
Sbjct: 110 ICTNTVQGHSCTCKPGY-VGNGTICRAF--CEEG---CRYGG--TCVAPNKCVCPSGFT- 160
Query: 266 TADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG------WKLVGRRCVDR 318
G +C +D+DEC E C + C N G + C C +G + L G C+D
Sbjct: 161 ---GSHCEKDIDECSEGIIEC--HNHSRCVNLPGWHHCECRSGFHDDGTYSLSGESCIDI 215
Query: 319 DECKELPYVCAGGE-CRNFNGGYVCECPAG 347
DEC + C C N GG+ C CP G
Sbjct: 216 DECALRTHTCWNDSACINLAGGFDCLCPCG 245
Score = 93.1 bits (221), Expect = 4e-18
Identities = 63/195 (32%), Positives = 79/195 (40%), Gaps = 26/195 (13%)
Query: 462 DGLSCVDADECALDPRIC-GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASC 520
D C D DECA C N C N G Y C C PG+ + D +C + DEC G+ +C
Sbjct: 46 DSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNC 105
Query: 521 TFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPE 578
C NT CTC GY +G CR E C + V C CP
Sbjct: 106 DENAICTNTVQGHSCTCKPGY--VGNGTICRAFCE-----EGCRYG-GTCVAPNKCVCPS 157
Query: 579 GYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP----SEDGTD 634
G+ + +D + E I EC C+N G C+C +GF S G
Sbjct: 158 GFTGSHCEKDIDECSEGIIECHNHSR------CVNLPGWHHCECRSGFHDDGTYSLSGES 211
Query: 635 CID-----RRTGTCY 644
CID RT TC+
Sbjct: 212 CIDIDECALRTHTCW 226
Score = 90.6 bits (215), Expect = 2e-17
Identities = 94/339 (27%), Positives = 127/339 (37%), Gaps = 41/339 (12%)
Query: 189 CRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC-RNG 246
C D+DEC+ C N C NLPG Y C C G+ + C + +EC G C N
Sbjct: 50 CEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENA 109
Query: 247 RCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
C NTV C C PGY +G CR C+E C G +C N +C C +
Sbjct: 110 ICTNTVQGHSCTCKPGYV--GNGTICRAF--CEE---GCRYGG--TCVAPN---KCVCPS 157
Query: 307 GWKLVGRRCV-DRDECKELPYVCAG-GECRNFNGGYVCECPAGWRFDKT------AAVCV 358
G+ G C D DEC E C C N G + CEC +G+ D T + + +
Sbjct: 158 GF--TGSHCEKDIDECSEGIIECHNHSRCVNLPGWHHCECRSGFHDDGTYSLSGESCIDI 215
Query: 359 DERKELCYDEWEAGRCHRARP----LQLARPEC---CCSEGA------AWGRYCERCPAP 405
DE + W C L P C C EG W +RC
Sbjct: 216 DECALRTHTCWNDSACINLAGGFDCLCPCGPSCSGDCPHEGGLKHNGQVWTLKEDRCSVC 275
Query: 406 DSAEFMRIC-QGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGL 464
+ C + N + DL C D V +C++ +G D + +
Sbjct: 276 SCKDGKIFCRRTACDCQNPSADL-FCCPECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQC 334
Query: 465 SCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
C++ E P C N +C T E +C P P
Sbjct: 335 RCLEG-EVDCWPLTCPNLSCEYT-AILEGECCPRCVSDP 371
Score = 83.0 bits (196), Expect = 4e-15
Identities = 75/238 (31%), Positives = 100/238 (42%), Gaps = 43/238 (18%)
Query: 225 GPNNDCVDVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPH 283
G + C D++EC C N C N G +RC+C PGY + D +C + DEC H
Sbjct: 45 GDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQH 103
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVC 342
C D N CTNT G+ C+C G+ VG + R C+E C GG C N C
Sbjct: 104 NC--DENAICTNTVQGHSCTCKPGY--VGNGTICRAFCEE---GCRYGGTCVAPN---KC 153
Query: 343 ECPAGWRFDKTAAVCVDERKELCYDEWEAG--RCHRARPLQLARPECCCSEGAAWGRYCE 400
CP+G+ T + C K++ DE G CH C W +CE
Sbjct: 154 VCPSGF----TGSHC---EKDI--DECSEGIIECHN---------HSRCVNLPGW-HHCE 194
Query: 401 -RCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDG 456
R D + + + D+DEC +R C C+N G F C CP G
Sbjct: 195 CRSGFHDDGTYSLSGESCI-------DIDECALRTHTCWNDSACINLAGGFDCLCPCG 245
Score = 74.5 bits (175), Expect = 1e-12
Identities = 86/288 (29%), Positives = 109/288 (37%), Gaps = 44/288 (15%)
Query: 69 DECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
DEC C C +T G C C GY + T +CR C G CR CV
Sbjct: 96 DECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGT--ICRAF--CEEG---CRYGGTCV 148
Query: 128 NLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRI-C-DHGDCRNTIGSYRCECKPG--- 181
P +C CP G+ T S CE D+DEC + I C +H C N G + CEC+ G
Sbjct: 149 -APN--KCVCPSGF--TGS--HCEKDIDECSEGIIECHNHSRCVNLPGWHHCECRSGFHD 201
Query: 182 ---YTLRENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECR 237
Y+L C D+DEC+ C N C NL G + C C G + DC +
Sbjct: 202 DGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPCG--PSCSGDCPHEGGLK 259
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTL----TADGRN-CRDVDECDELPHPCGRDGNPS 292
G V R +V C C G D +N D+ C E C
Sbjct: 260 HNGQVWTLKEDRCSV----CSCKDGKIFCRRTACDCQNPSADLFCCPE----CDTRVTSQ 311
Query: 293 CTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGY 340
C + NG G W ++C C E C C N + Y
Sbjct: 312 CLDQNGHKLYRSGDNWTHSCQQC----RCLEGEVDCWPLTCPNLSCEY 355
Score = 68.5 bits (160), Expect = 9e-11
Identities = 56/190 (29%), Positives = 82/190 (43%), Gaps = 28/190 (14%)
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGNGT-CSNTRGGYECQCS 496
GG CV + +C CP G+ G C D DEC+ C N + C N G + C+C
Sbjct: 144 GGTCVAPN---KCVCPSGFT----GSHCEKDIDECSEGIIECHNHSRCVNLPGWHHCECR 196
Query: 497 PGFTQG-----PDQTCVDVDECAEGRASC--TFRCHNTAGSFRCTCPYGYAVAADGVHCR 549
GF ++C+D+DECA +C C N AG F C CP G + + D H
Sbjct: 197 SGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPCGPSCSGDCPHEG 256
Query: 550 DIDECVQEPRVCPHACENVVGSYICKCPEG---YRRTSAPQDSENACEDINECEEQEDLC 606
+ Q + C +C C +G RRT+ D +N D+ C E +
Sbjct: 257 GLKHNGQVWTLKEDRCS------VCSCKDGKIFCRRTAC--DCQNPSADLFCCPECDTRV 308
Query: 607 SGGVCINTDG 616
+ C++ +G
Sbjct: 309 T-SQCLDQNG 317
Score = 67.7 bits (158), Expect = 2e-10
Identities = 32/85 (37%), Positives = 44/85 (51%), Gaps = 5/85 (5%)
Query: 778 CADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ- 834
C D+DECA + C + +C N G Y C C GY + D +C + DEC H C +
Sbjct: 50 CEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNCDEN 108
Query: 835 -ICSNTEGSYECSCEDGYEKRGDAC 858
IC+NT + C+C+ GY G C
Sbjct: 109 AICTNTVQGHSCTCKPGYVGNGTIC 133
Score = 64.9 bits (151), Expect = 1e-09
Identities = 41/111 (36%), Positives = 52/111 (46%), Gaps = 14/111 (12%)
Query: 756 GLC-APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYE 811
G C AP + CVC G+ G C D+DEC+ C C N G + C CR+G+
Sbjct: 145 GTCVAPNK--CVCPSGF--TGSHCEKDIDECSEGIIECHNHSRCVNLPGWHHCECRSGFH 200
Query: 812 LDE----DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGD 856
D G +C D+DEC THTC C N G ++C C G GD
Sbjct: 201 DDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPCGPSCSGD 251
Score = 52.0 bits (119), Expect = 9e-06
Identities = 32/85 (37%), Positives = 40/85 (47%), Gaps = 13/85 (15%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGY-RPAGEVCADVDECAVRPPPCDQ--LC 795
D+DECAA C PG +RC C PGY R C + DEC CD+ +C
Sbjct: 52 DIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAIC 111
Query: 796 HNTDGSYDCLCRTGYELDEDGANCR 820
NT + C C+ GY +G CR
Sbjct: 112 TNTVQGHSCTCKPGYV--GNGTICR 134
Score = 50.4 bits (115), Expect = 3e-05
Identities = 34/99 (34%), Positives = 41/99 (41%), Gaps = 14/99 (14%)
Query: 760 PGRFRCVCGPG------YRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYE 811
PG C C G Y +GE C D+DECA+R C D C N G +DCLC G
Sbjct: 188 PGWHHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPCGPS 247
Query: 812 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
D C + H Q + CSC+DG
Sbjct: 248 CSGD---CPHEGGLK---HNGQVWTLKEDRCSVCSCKDG 280
Score = 43.2 bits (97), Expect = 0.004
Identities = 18/44 (40%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 815 DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGD 856
D A C D+DEC H C +C N G Y C C GY + D
Sbjct: 46 DSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDD 89
Score = 40.3 bits (90), Expect = 0.028
Identities = 27/94 (28%), Positives = 38/94 (40%), Gaps = 13/94 (13%)
Query: 765 CVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDVD 823
C C PGY G +C E R C + C+C +G+ G++C +D+D
Sbjct: 120 CTCKPGYVGNGTICRAFCEEGCR---YGGTCVAPN---KCVCPSGFT----GSHCEKDID 169
Query: 824 ECERDTHTCQQI--CSNTEGSYECSCEDGYEKRG 855
EC C C N G + C C G+ G
Sbjct: 170 ECSEGIIECHNHSRCVNLPGWHHCECRSGFHDDG 203
Score = 39.9 bits (89), Expect = 0.038
Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Query: 583 TSAPQDSENACEDINECEEQEDLC-SGGVCINTDGSFLCDCDAGFEPSED 631
TS + CEDI+EC + C + VC+N G + CDC G+ +D
Sbjct: 40 TSLSRGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDD 89
>AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precursor
protein.
Length = 1406
Score = 134 bits (323), Expect = 2e-30
Identities = 134/464 (28%), Positives = 191/464 (41%), Gaps = 76/464 (16%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS--WGRPPCRGMAQCVNLPG--AFECRC 137
TC D C C D ++L +D D PC+G A CVN PG +F C+C
Sbjct: 44 TCKDFSKDNDCSCS-----DTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKC 98
Query: 138 PPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYR-CECKPGYTLRENVCR-DVDE 194
PPGY T CE + CG + C HG + Y C C GY R C D DE
Sbjct: 99 PPGYSGT----ICETTIGSCG-KNSCQHGGICHQDPIYPVCICPAGYAGR--FCEIDHDE 151
Query: 195 CSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTV 252
C+ C+NG C++ Y C C G++ G + D ++V+EC C+N C N +
Sbjct: 152 CA--SSPCQNGAVCQDGIDGYSCFCVPGYQ-GRHCD-LEVDECASD--PCKNEATCLNEI 205
Query: 253 GSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
G + C C Y+ G NC ++DEC PC +C + G Y C C G+ +
Sbjct: 206 GRYTCICPHNYS----GVNCELEIDEC--WSQPC--LNGATCQDALGAYFCDCAPGF--L 255
Query: 312 GRRC-VDRDECKELPYVCAGGECRNFNGGYVCECP----AGWRFDKTAAVCVDE---RKE 363
G C ++ DEC P + GG C + Y C C G + +C +
Sbjct: 256 GDHCELNTDECASQPCL-HGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNA 314
Query: 364 LCYDEWEAGRCH-----RARPLQLARPEC----C-----CSEGAAWGRYCERCPAPDS-- 407
C D + CH ++ EC C C E ++ +Y P S
Sbjct: 315 TCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFS 374
Query: 408 ----AEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAP- 461
+ ++ ICQ G + +D++EC P C GG C N G++ C CP +
Sbjct: 375 YHEASGYVCICQPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHCPFDNLSRTF 432
Query: 462 -DGLSCVDADECALDPRICGNGTC----SNTRGGYECQCSPGFT 500
G C D + NGTC + + G+ C C G+T
Sbjct: 433 YGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYT 476
Score = 132 bits (319), Expect = 5e-30
Identities = 112/364 (30%), Positives = 157/364 (43%), Gaps = 45/364 (12%)
Query: 8 QSCAGAVGVP-QTKYLCCCSVGHAWGAPCE----ACPPRGSPAHTALCGEKP--GEYINP 60
Q A V P + +LC C G++ G CE +C + S H +C + P I P
Sbjct: 80 QGSATCVNTPGERSFLCKCPPGYS-GTICETTIGSCG-KNSCQHGGICHQDPIYPVCICP 137
Query: 61 VTNETK--PIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGR 117
+ ID + C+ G C D G+ C C GY+ H +VDEC+
Sbjct: 138 AGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQG---RHCDLEVDECA--S 192
Query: 118 PPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRC 176
PC+ A C+N G + C CP Y S CE ++DEC Q + C++ +G+Y C
Sbjct: 193 DPCKNEATCLNEIGRYTCICPHNY----SGVNCELEIDECWSQPCLNGATCQDALGAYFC 248
Query: 177 ECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNEC 236
+C PG+ L ++ + DEC+ +P G C + Y C+C G + C +
Sbjct: 249 DCAPGF-LGDHCELNTDECA-SQPCLHGGLCVDGENRYSCNCTGSGFTGTH--CETLMPL 304
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGYT-------LTADGRN-CRDVDECDEL--PHPCG 286
N C ++V ++ C C PGYT L N C+ EC EL G
Sbjct: 305 CWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYG 364
Query: 287 R-DGNPSCTNTN--GGYECSCGAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYV 341
R G PS + + GY C C G+ G C D +EC P C GG C N G Y
Sbjct: 365 RITGLPSSFSYHEASGYVCICQPGF--TGIHCEEDVNECSSNP--CQNGGTCENLPGNYT 420
Query: 342 CECP 345
C CP
Sbjct: 421 CHCP 424
Score = 112 bits (270), Expect = 4e-24
Identities = 129/466 (27%), Positives = 180/466 (38%), Gaps = 69/466 (14%)
Query: 204 NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVG--SFRCECAP 261
N TC++ C C D + DC ++ + + C NT G SF C+C P
Sbjct: 42 NSTCKDFSKDNDCSCSDTAN-NLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPP 100
Query: 262 GYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRD 319
GY+ G C + C + + C G C C C AG+ GR C +D D
Sbjct: 101 GYS----GTICETTIGSCGK--NSCQHGG--ICHQDPIYPVCICPAGY--AGRFCEIDHD 150
Query: 320 ECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVDE-RKELCYDEW----EAGR 373
EC P C G C++ GY C C G++ + + VDE + C +E E GR
Sbjct: 151 ECASSP--CQNGAVCQDGIDGYSCFCVPGYQ-GRHCDLEVDECASDPCKNEATCLNEIGR 207
Query: 374 CHRARPLQLARPECCCSEGAAWGRYC---ERCPAPDSAEFMRICQGGMGRPNLTQDLDEC 430
P + C W + C C A F G +G + + DEC
Sbjct: 208 YTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG-DHCELNTDEC 266
Query: 431 RVRPDVCV-GGRCVNTDGSFRCECP-DGYVLAPDGLSCVDADECALDPRICGNGTCSNTR 488
+P C+ GG CV+ + + C C G+ G C N TC ++
Sbjct: 267 ASQP--CLHGGLCVDGENRYSCNCTGSGFT----GTHCETLMPLCWSKPCHNNATCEDSV 320
Query: 489 GGYECQCSPGFTQGP---------DQTCVDVDECAE-------GRAS---CTFRCHNTAG 529
Y C C PG+T C EC E GR + +F H +G
Sbjct: 321 DNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASG 380
Query: 530 SFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQD 588
+ C C G+ G+HC D++EC P CEN+ G+Y C CP + S
Sbjct: 381 -YVCICQPGFT----GIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP--FDNLSRTFY 433
Query: 589 SENACEDI-NECEEQEDLCSGGVCIN--TDG--SFLCDCDAGFEPS 629
C DI C Q+ L + G CI DG F C C +G+ S
Sbjct: 434 GGRDCSDILLGCTHQQCL-NNGTCIPHFQDGQHGFSCLCPSGYTGS 478
Score = 88.6 bits (210), Expect = 8e-17
Identities = 64/216 (29%), Positives = 93/216 (43%), Gaps = 27/216 (12%)
Query: 107 CRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG 165
C ++ C+ PC C ++ ++ C CP G+ S CE ++DEC C HG
Sbjct: 1137 CLQLNVCNSN--PCLHGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECFSNP-CIHG 1189
Query: 166 DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKA 224
+C + + +Y C C+PGYT N D+D C + C NG TC + Y C C F
Sbjct: 1190 NCSDRVAAYHCTCEPGYT-GVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLCFGNFTG 1246
Query: 225 G-PNNDCVDVNEC--REGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECD 279
+ C + + C N G C +C C PG+T G C +D+DEC
Sbjct: 1247 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT----GEWCEKDIDEC- 1301
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
PC G C + ++C C + G RC
Sbjct: 1302 -ASDPCVNGG--LCQDLLNKFQCLCDVAF--AGERC 1332
Score = 72.9 bits (171), Expect = 4e-12
Identities = 65/240 (27%), Positives = 95/240 (39%), Gaps = 28/240 (11%)
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDG 463
P +F++I + L L+ C P C+ GG C + S+ C CP G+ G
Sbjct: 1120 PQEEQFLKISTNSVVTGCL--QLNVCNSNP--CLHGGNCEDIYSSYHCSCPLGW----SG 1171
Query: 464 LSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRASCT 521
C ++ DEC +P C +G CS+ Y C C PG+T C VD+D C + +
Sbjct: 1172 KHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEPGYT---GVNCEVDIDNCQSHQCANG 1226
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + + C C + G CR + VC + N+ C E
Sbjct: 1227 ATCISHTNGYSCLCFGNFT----GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1279
Query: 582 RTSA---PQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
P + CE DI+EC + +GG+C + F C CD F D D
Sbjct: 1280 ELKCMCRPGFTGEWCEKDIDEC-ASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
Score = 67.7 bits (158), Expect = 2e-10
Identities = 64/231 (27%), Positives = 92/231 (39%), Gaps = 43/231 (18%)
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG 330
C ++ C+ +PC GN C + Y CSC GW G+ C ++ DEC P C
Sbjct: 1137 CLQLNVCNS--NPCLHGGN--CEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIH 1188
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC-HRARPLQLARPECCC 389
G C + Y C C G+ T C E+ D ++ +C + A + C
Sbjct: 1189 GNCSDRVAAYHCTCEPGY----TGVNC-----EVDIDNCQSHQCANGATCISHTNGYSCL 1239
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
G G++C + P + +C G + NLT C GG C
Sbjct: 1240 CFGNFTGKFCRQSRLPST-----VC--GNEKTNLT-----C------YNGGNCTEFQTEL 1281
Query: 450 RCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGF 499
+C C G+ G C D DECA DP + G G C + ++C C F
Sbjct: 1282 KCMCRPGFT----GEWCEKDIDECASDPCVNG-GLCQDLLNKFQCLCDVAF 1327
Score = 67.7 bits (158), Expect = 2e-10
Identities = 45/159 (28%), Positives = 66/159 (41%), Gaps = 13/159 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P C G C D + C C+ GY N D+D C C A C+
Sbjct: 1178 IDECFSNP--CIHGNCSDRVAAYHCTCEPGYTGVNCE---VDIDNCQ--SHQCANGATCI 1230
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQR---IC-DHGDCRNTIGSYRCECKPGYT 183
+ + C C + CG+++ C + G+C +C C+PG+T
Sbjct: 1231 SHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1290
Query: 184 LRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
E +D+DEC+ P G C++L + C CD F
Sbjct: 1291 -GEWCEKDIDECASD-PCVNGGLCQDLLNKFQCLCDVAF 1327
Score = 66.9 bits (156), Expect = 3e-10
Identities = 43/120 (35%), Positives = 55/120 (45%), Gaps = 16/120 (13%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D DECA+ P +C G + C C PGY+ G C +VDECA P + C N
Sbjct: 148 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQ--GRHCDLEVDECASDPCKNEATCLNEI 205
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
G Y C+C Y G NC ++DEC C + G+Y C C G+ GD C
Sbjct: 206 GRYTCICPHNY----SGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGF--LGDHC 259
Score = 66.9 bits (156), Expect = 3e-10
Identities = 62/234 (26%), Positives = 90/234 (38%), Gaps = 35/234 (14%)
Query: 59 NPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRP 118
N V ++ C+ P L G C D + + C C G+ + H ++DEC + P
Sbjct: 1131 NSVVTGCLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGW---SGKHCELNIDEC-FSNP 1185
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCE 177
G C + A+ C C PGY CE D+D C + + C + Y C
Sbjct: 1186 CIHG--NCSDRVAAYHCTCEPGYTGV----NCEVDIDNCQSHQCANGATCISHTNGYSCL 1239
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRN----------GTCENLPGAYLCHCDDGFKAGPN 227
C +T CR + P VC N G C C C GF G
Sbjct: 1240 CFGNFT--GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF-TGEW 1293
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDEL 281
+ D++EC V G C++ + F+C C + G C +VD D+L
Sbjct: 1294 CE-KDIDECASDPCV-NGGLCQDLLNKFQCLCDVAFA----GERC-EVDLADDL 1340
Score = 54.4 bits (125), Expect = 2e-06
Identities = 68/243 (27%), Positives = 89/243 (36%), Gaps = 47/243 (19%)
Query: 9 SCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPR--GSPA-HTALCGEKPGEYINPVTNET 65
+C A+G Y C C+ G G CE P H LC + Y T
Sbjct: 238 TCQDALGA----YFCDCAPGFL-GDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSG 292
Query: 66 KPIDECDIMPQLC--KP----GTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRP 118
C+ + LC KP TC D+ + C C GY T C D++EC+
Sbjct: 293 FTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY----TGAQCEIDLNECNSN-- 346
Query: 119 PCRGMAQCVNL------------PGAFE--------CRCPPGYRLTPSLDECEDVDECGD 158
PC+ +CV L P +F C C PG+ + EDV+EC
Sbjct: 347 PCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFT---GIHCEEDVNECSS 403
Query: 159 QRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHC 218
+ G C N G+Y C C P L D CS C + C N G + H
Sbjct: 404 NPCQNGGTCENLPGNYTCHC-PFDNLSRTFYGGRD-CSDILLGCTHQQCLN-NGTCIPHF 460
Query: 219 DDG 221
DG
Sbjct: 461 QDG 463
Score = 44.4 bits (100), Expect = 0.002
Identities = 35/113 (30%), Positives = 50/113 (44%), Gaps = 13/113 (11%)
Query: 747 DVDECAAIPGL----C--APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
++DEC + P L C A G + C C PG+ G+ C + DECA +P LC + +
Sbjct: 224 EIDECWSQPCLNGATCQDALGAYFCDCAPGF--LGDHCELNTDECASQPCLHGGLCVDGE 281
Query: 800 GSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
Y C C TG G +C + C C ++ +Y C C GY
Sbjct: 282 NRYSCNC-TGSGF--TGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY 331
Score = 39.9 bits (89), Expect = 0.038
Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 20/100 (20%)
Query: 765 CVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLC------RTGYELDEDGA 817
C+C PG+ G C DV+EC+ P C N G+Y C C RT Y G
Sbjct: 383 CICQPGF--TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFY----GGR 436
Query: 818 NCRDV------DECERDTHTCQQICSNTEGSYECSCEDGY 851
+C D+ +C + TC + + + C C GY
Sbjct: 437 DCSDILLGCTHQQC-LNNGTCIPHFQDGQHGFSCLCPSGY 475
Score = 39.1 bits (87), Expect = 0.066
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
Query: 764 RCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
+C+C PG+ GE C D+DECA P LC + + CLC +
Sbjct: 1282 KCMCRPGF--TGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1327
Score = 38.7 bits (86), Expect = 0.087
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 6/75 (8%)
Query: 778 CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQIC 836
C ++ C P C + SY C C G+ G +C ++DEC + C
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWS----GKHCELNIDECFSNP-CIHGNC 1191
Query: 837 SNTEGSYECSCEDGY 851
S+ +Y C+CE GY
Sbjct: 1192 SDRVAAYHCTCEPGY 1206
Score = 37.1 bits (82), Expect = 0.27
Identities = 32/119 (26%), Positives = 45/119 (37%), Gaps = 20/119 (16%)
Query: 747 DVDECAAIP---GLCAP--GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDG 800
++DEC + P G C+ + C C PGY G C D+D C C +
Sbjct: 1177 NIDECFSNPCIHGNCSDRVAAYHCTCEPGY--TGVNCEVDIDNCQSHQCANGATCISHTN 1234
Query: 801 SYDCLCRTGYELDEDGANCRD------VDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
Y CLC + G CR V E+ TC C+ + +C C G+
Sbjct: 1235 GYSCLCFGNF----TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF 1289
Score = 33.1 bits (72), Expect = 4.3
Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 795 CHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C C+CR G+ G C +D+DEC D +C + ++C C+ +
Sbjct: 1274 CTEFQTELKCMCRPGFT----GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF-- 1327
Query: 854 RGDAC 858
G+ C
Sbjct: 1328 AGERC 1332
Score = 32.7 bits (71), Expect = 5.7
Identities = 19/72 (26%), Positives = 27/72 (37%), Gaps = 8/72 (11%)
Query: 505 QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA 564
Q C + C CH+ F C+CP G C ++ C P CPH
Sbjct: 883 QGCAGDNSCKSNPCHNGGVCHSRWDDFSCSCP----ALTSGKACEEVQWCGFSP--CPHG 936
Query: 565 --CENVVGSYIC 574
C+ V+ + C
Sbjct: 937 AQCQPVLQGFEC 948
>AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precursor
protein.
Length = 1376
Score = 134 bits (323), Expect = 2e-30
Identities = 134/464 (28%), Positives = 191/464 (41%), Gaps = 76/464 (16%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS--WGRPPCRGMAQCVNLPG--AFECRC 137
TC D C C D ++L +D D PC+G A CVN PG +F C+C
Sbjct: 44 TCKDFSKDNDCSCS-----DTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKC 98
Query: 138 PPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYR-CECKPGYTLRENVCR-DVDE 194
PPGY T CE + CG + C HG + Y C C GY R C D DE
Sbjct: 99 PPGYSGT----ICETTIGSCG-KNSCQHGGICHQDPIYPVCICPAGYAGR--FCEIDHDE 151
Query: 195 CSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTV 252
C+ C+NG C++ Y C C G++ G + D ++V+EC C+N C N +
Sbjct: 152 CA--SSPCQNGAVCQDGIDGYSCFCVPGYQ-GRHCD-LEVDECASD--PCKNEATCLNEI 205
Query: 253 GSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
G + C C Y+ G NC ++DEC PC +C + G Y C C G+ +
Sbjct: 206 GRYTCICPHNYS----GVNCELEIDEC--WSQPC--LNGATCQDALGAYFCDCAPGF--L 255
Query: 312 GRRC-VDRDECKELPYVCAGGECRNFNGGYVCECP----AGWRFDKTAAVCVDE---RKE 363
G C ++ DEC P + GG C + Y C C G + +C +
Sbjct: 256 GDHCELNTDECASQPCL-HGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNA 314
Query: 364 LCYDEWEAGRCH-----RARPLQLARPEC----C-----CSEGAAWGRYCERCPAPDS-- 407
C D + CH ++ EC C C E ++ +Y P S
Sbjct: 315 TCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFS 374
Query: 408 ----AEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAP- 461
+ ++ ICQ G + +D++EC P C GG C N G++ C CP +
Sbjct: 375 YHEASGYVCICQPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHCPFDNLSRTF 432
Query: 462 -DGLSCVDADECALDPRICGNGTC----SNTRGGYECQCSPGFT 500
G C D + NGTC + + G+ C C G+T
Sbjct: 433 YGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYT 476
Score = 132 bits (319), Expect = 5e-30
Identities = 112/364 (30%), Positives = 157/364 (43%), Gaps = 45/364 (12%)
Query: 8 QSCAGAVGVP-QTKYLCCCSVGHAWGAPCE----ACPPRGSPAHTALCGEKP--GEYINP 60
Q A V P + +LC C G++ G CE +C + S H +C + P I P
Sbjct: 80 QGSATCVNTPGERSFLCKCPPGYS-GTICETTIGSCG-KNSCQHGGICHQDPIYPVCICP 137
Query: 61 VTNETK--PIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGR 117
+ ID + C+ G C D G+ C C GY+ H +VDEC+
Sbjct: 138 AGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQG---RHCDLEVDECA--S 192
Query: 118 PPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRC 176
PC+ A C+N G + C CP Y S CE ++DEC Q + C++ +G+Y C
Sbjct: 193 DPCKNEATCLNEIGRYTCICPHNY----SGVNCELEIDECWSQPCLNGATCQDALGAYFC 248
Query: 177 ECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNEC 236
+C PG+ L ++ + DEC+ +P G C + Y C+C G + C +
Sbjct: 249 DCAPGF-LGDHCELNTDECA-SQPCLHGGLCVDGENRYSCNCTGSGFTGTH--CETLMPL 304
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGYT-------LTADGRN-CRDVDECDEL--PHPCG 286
N C ++V ++ C C PGYT L N C+ EC EL G
Sbjct: 305 CWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYG 364
Query: 287 R-DGNPSCTNTN--GGYECSCGAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYV 341
R G PS + + GY C C G+ G C D +EC P C GG C N G Y
Sbjct: 365 RITGLPSSFSYHEASGYVCICQPGF--TGIHCEEDVNECSSNP--CQNGGTCENLPGNYT 420
Query: 342 CECP 345
C CP
Sbjct: 421 CHCP 424
Score = 112 bits (270), Expect = 4e-24
Identities = 129/466 (27%), Positives = 180/466 (38%), Gaps = 69/466 (14%)
Query: 204 NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVG--SFRCECAP 261
N TC++ C C D + DC ++ + + C NT G SF C+C P
Sbjct: 42 NSTCKDFSKDNDCSCSDTAN-NLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPP 100
Query: 262 GYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRD 319
GY+ G C + C + + C G C C C AG+ GR C +D D
Sbjct: 101 GYS----GTICETTIGSCGK--NSCQHGG--ICHQDPIYPVCICPAGY--AGRFCEIDHD 150
Query: 320 ECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVDE-RKELCYDEW----EAGR 373
EC P C G C++ GY C C G++ + + VDE + C +E E GR
Sbjct: 151 ECASSP--CQNGAVCQDGIDGYSCFCVPGYQ-GRHCDLEVDECASDPCKNEATCLNEIGR 207
Query: 374 CHRARPLQLARPECCCSEGAAWGRYC---ERCPAPDSAEFMRICQGGMGRPNLTQDLDEC 430
P + C W + C C A F G +G + + DEC
Sbjct: 208 YTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG-DHCELNTDEC 266
Query: 431 RVRPDVCV-GGRCVNTDGSFRCECP-DGYVLAPDGLSCVDADECALDPRICGNGTCSNTR 488
+P C+ GG CV+ + + C C G+ G C N TC ++
Sbjct: 267 ASQP--CLHGGLCVDGENRYSCNCTGSGFT----GTHCETLMPLCWSKPCHNNATCEDSV 320
Query: 489 GGYECQCSPGFTQGP---------DQTCVDVDECAE-------GRAS---CTFRCHNTAG 529
Y C C PG+T C EC E GR + +F H +G
Sbjct: 321 DNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASG 380
Query: 530 SFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQD 588
+ C C G+ G+HC D++EC P CEN+ G+Y C CP + S
Sbjct: 381 -YVCICQPGFT----GIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP--FDNLSRTFY 433
Query: 589 SENACEDI-NECEEQEDLCSGGVCIN--TDG--SFLCDCDAGFEPS 629
C DI C Q+ L + G CI DG F C C +G+ S
Sbjct: 434 GGRDCSDILLGCTHQQCL-NNGTCIPHFQDGQHGFSCLCPSGYTGS 478
Score = 88.6 bits (210), Expect = 8e-17
Identities = 64/216 (29%), Positives = 93/216 (43%), Gaps = 27/216 (12%)
Query: 107 CRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG 165
C ++ C+ PC C ++ ++ C CP G+ S CE ++DEC C HG
Sbjct: 1137 CLQLNVCNSN--PCLHGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECFSNP-CIHG 1189
Query: 166 DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKA 224
+C + + +Y C C+PGYT N D+D C + C NG TC + Y C C F
Sbjct: 1190 NCSDRVAAYHCTCEPGYT-GVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLCFGNFTG 1246
Query: 225 G-PNNDCVDVNEC--REGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECD 279
+ C + + C N G C +C C PG+T G C +D+DEC
Sbjct: 1247 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT----GEWCEKDIDEC- 1301
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
PC G C + ++C C + G RC
Sbjct: 1302 -ASDPCVNGG--LCQDLLNKFQCLCDVAF--AGERC 1332
Score = 72.1 bits (169), Expect = 8e-12
Identities = 63/229 (27%), Positives = 93/229 (40%), Gaps = 28/229 (12%)
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDG 463
P +F++I + L L+ C P C+ GG C + S+ C CP G+ G
Sbjct: 1120 PQEEQFLKISTNSVVTGCL--QLNVCNSNP--CLHGGNCEDIYSSYHCSCPLGW----SG 1171
Query: 464 LSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRASCT 521
C ++ DEC +P C +G CS+ Y C C PG+T C VD+D C + +
Sbjct: 1172 KHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEPGYT---GVNCEVDIDNCQSHQCANG 1226
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + + C C + G CR + VC + N+ C E
Sbjct: 1227 ATCISHTNGYSCLCFGNFT----GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1279
Query: 582 RTSA---PQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
P + CE DI+EC + +GG+C + F C CD F
Sbjct: 1280 ELKCMCRPGFTGEWCEKDIDEC-ASDPCVNGGLCQDLLNKFQCLCDVAF 1327
Score = 68.1 bits (159), Expect = 1e-10
Identities = 50/171 (29%), Positives = 73/171 (42%), Gaps = 15/171 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P C G C D + C C+ GY N D+D C C A C+
Sbjct: 1178 IDECFSNP--CIHGNCSDRVAAYHCTCEPGYTGVNCE---VDIDNCQ--SHQCANGATCI 1230
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQR---IC-DHGDCRNTIGSYRCECKPGYT 183
+ + C C + CG+++ C + G+C +C C+PG+T
Sbjct: 1231 SHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1290
Query: 184 LRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVN 234
E +D+DEC+ P G C++L + C CD F AG + VDV+
Sbjct: 1291 -GEWCEKDIDECASD-PCVNGGLCQDLLNKFQCLCDVAF-AGERCE-VDVS 1337
Score = 67.7 bits (158), Expect = 2e-10
Identities = 64/231 (27%), Positives = 92/231 (39%), Gaps = 43/231 (18%)
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG 330
C ++ C+ +PC GN C + Y CSC GW G+ C ++ DEC P C
Sbjct: 1137 CLQLNVCNS--NPCLHGGN--CEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIH 1188
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC-HRARPLQLARPECCC 389
G C + Y C C G+ T C E+ D ++ +C + A + C
Sbjct: 1189 GNCSDRVAAYHCTCEPGY----TGVNC-----EVDIDNCQSHQCANGATCISHTNGYSCL 1239
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
G G++C + P + +C G + NLT C GG C
Sbjct: 1240 CFGNFTGKFCRQSRLPST-----VC--GNEKTNLT-----C------YNGGNCTEFQTEL 1281
Query: 450 RCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGF 499
+C C G+ G C D DECA DP + G G C + ++C C F
Sbjct: 1282 KCMCRPGFT----GEWCEKDIDECASDPCVNG-GLCQDLLNKFQCLCDVAF 1327
Score = 66.9 bits (156), Expect = 3e-10
Identities = 43/120 (35%), Positives = 55/120 (45%), Gaps = 16/120 (13%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D DECA+ P +C G + C C PGY+ G C +VDECA P + C N
Sbjct: 148 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQ--GRHCDLEVDECASDPCKNEATCLNEI 205
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
G Y C+C Y G NC ++DEC C + G+Y C C G+ GD C
Sbjct: 206 GRYTCICPHNY----SGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGF--LGDHC 259
Score = 64.1 bits (149), Expect = 2e-09
Identities = 56/212 (26%), Positives = 81/212 (38%), Gaps = 30/212 (14%)
Query: 59 NPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRP 118
N V ++ C+ P L G C D + + C C G+ + H ++DEC + P
Sbjct: 1131 NSVVTGCLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGW---SGKHCELNIDEC-FSNP 1185
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCE 177
G C + A+ C C PGY CE D+D C + + C + Y C
Sbjct: 1186 CIHG--NCSDRVAAYHCTCEPGYTGV----NCEVDIDNCQSHQCANGATCISHTNGYSCL 1239
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRN----------GTCENLPGAYLCHCDDGFKAGPN 227
C +T CR + P VC N G C C C GF G
Sbjct: 1240 CFGNFT--GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF-TGEW 1293
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCEC 259
+ D++EC V G C++ + F+C C
Sbjct: 1294 CE-KDIDECASDPCV-NGGLCQDLLNKFQCLC 1323
Score = 54.4 bits (125), Expect = 2e-06
Identities = 68/243 (27%), Positives = 89/243 (36%), Gaps = 47/243 (19%)
Query: 9 SCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPR--GSPA-HTALCGEKPGEYINPVTNET 65
+C A+G Y C C+ G G CE P H LC + Y T
Sbjct: 238 TCQDALGA----YFCDCAPGFL-GDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSG 292
Query: 66 KPIDECDIMPQLC--KP----GTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRP 118
C+ + LC KP TC D+ + C C GY T C D++EC+
Sbjct: 293 FTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY----TGAQCEIDLNECNSN-- 346
Query: 119 PCRGMAQCVNL------------PGAFE--------CRCPPGYRLTPSLDECEDVDECGD 158
PC+ +CV L P +F C C PG+ + EDV+EC
Sbjct: 347 PCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFT---GIHCEEDVNECSS 403
Query: 159 QRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHC 218
+ G C N G+Y C C P L D CS C + C N G + H
Sbjct: 404 NPCQNGGTCENLPGNYTCHC-PFDNLSRTFYGGRD-CSDILLGCTHQQCLN-NGTCIPHF 460
Query: 219 DDG 221
DG
Sbjct: 461 QDG 463
Score = 48.8 bits (111), Expect = 8e-05
Identities = 42/181 (23%), Positives = 67/181 (37%), Gaps = 11/181 (6%)
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS-AEFMRICQGGMGRPNL 423
C D + + C + PL + C + + C D A + C+ G N
Sbjct: 1154 CEDIYSSYHC--SCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNC 1211
Query: 424 TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPR--ICGN 481
D+D C+ G C++ + C C + S + + C + C N
Sbjct: 1212 EVDIDNCQSH-QCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYN 1270
Query: 482 G-TCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRASCTFRCHNTAGSFRCTCPYGY 539
G C+ + +C C PGFT + C D+DECA C + F+C C +
Sbjct: 1271 GGNCTEFQTELKCMCRPGFT---GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1327
Query: 540 A 540
A
Sbjct: 1328 A 1328
Score = 44.4 bits (100), Expect = 0.002
Identities = 35/113 (30%), Positives = 50/113 (44%), Gaps = 13/113 (11%)
Query: 747 DVDECAAIPGL----C--APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
++DEC + P L C A G + C C PG+ G+ C + DECA +P LC + +
Sbjct: 224 EIDECWSQPCLNGATCQDALGAYFCDCAPGF--LGDHCELNTDECASQPCLHGGLCVDGE 281
Query: 800 GSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
Y C C TG G +C + C C ++ +Y C C GY
Sbjct: 282 NRYSCNC-TGSGF--TGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY 331
Score = 39.9 bits (89), Expect = 0.038
Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 20/100 (20%)
Query: 765 CVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLC------RTGYELDEDGA 817
C+C PG+ G C DV+EC+ P C N G+Y C C RT Y G
Sbjct: 383 CICQPGF--TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFY----GGR 436
Query: 818 NCRDV------DECERDTHTCQQICSNTEGSYECSCEDGY 851
+C D+ +C + TC + + + C C GY
Sbjct: 437 DCSDILLGCTHQQC-LNNGTCIPHFQDGQHGFSCLCPSGY 475
Score = 39.1 bits (87), Expect = 0.066
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
Query: 764 RCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
+C+C PG+ GE C D+DECA P LC + + CLC +
Sbjct: 1282 KCMCRPGF--TGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1327
Score = 38.7 bits (86), Expect = 0.087
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 6/75 (8%)
Query: 778 CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQIC 836
C ++ C P C + SY C C G+ G +C ++DEC + C
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWS----GKHCELNIDECFSNP-CIHGNC 1191
Query: 837 SNTEGSYECSCEDGY 851
S+ +Y C+CE GY
Sbjct: 1192 SDRVAAYHCTCEPGY 1206
Score = 37.1 bits (82), Expect = 0.27
Identities = 32/119 (26%), Positives = 45/119 (37%), Gaps = 20/119 (16%)
Query: 747 DVDECAAIP---GLCAP--GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDG 800
++DEC + P G C+ + C C PGY G C D+D C C +
Sbjct: 1177 NIDECFSNPCIHGNCSDRVAAYHCTCEPGY--TGVNCEVDIDNCQSHQCANGATCISHTN 1234
Query: 801 SYDCLCRTGYELDEDGANCRD------VDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
Y CLC + G CR V E+ TC C+ + +C C G+
Sbjct: 1235 GYSCLCFGNF----TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF 1289
Score = 33.1 bits (72), Expect = 4.3
Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 795 CHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C C+CR G+ G C +D+DEC D +C + ++C C+ +
Sbjct: 1274 CTEFQTELKCMCRPGFT----GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF-- 1327
Query: 854 RGDAC 858
G+ C
Sbjct: 1328 AGERC 1332
Score = 32.7 bits (71), Expect = 5.7
Identities = 19/72 (26%), Positives = 27/72 (37%), Gaps = 8/72 (11%)
Query: 505 QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA 564
Q C + C CH+ F C+CP G C ++ C P CPH
Sbjct: 883 QGCAGDNSCKSNPCHNGGVCHSRWDDFSCSCP----ALTSGKACEEVQWCGFSP--CPHG 936
Query: 565 --CENVVGSYIC 574
C+ V+ + C
Sbjct: 937 AQCQPVLQGFEC 948
>AL513325-3|CAH72584.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 134 bits (323), Expect = 2e-30
Identities = 134/464 (28%), Positives = 191/464 (41%), Gaps = 76/464 (16%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS--WGRPPCRGMAQCVNLPG--AFECRC 137
TC D C C D ++L +D D PC+G A CVN PG +F C+C
Sbjct: 44 TCKDFSKDNDCSCS-----DTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKC 98
Query: 138 PPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYR-CECKPGYTLRENVCR-DVDE 194
PPGY T CE + CG + C HG + Y C C GY R C D DE
Sbjct: 99 PPGYSGT----ICETTIGSCG-KNSCQHGGICHQDPIYPVCICPAGYAGR--FCEIDHDE 151
Query: 195 CSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTV 252
C+ C+NG C++ Y C C G++ G + D ++V+EC C+N C N +
Sbjct: 152 CA--SSPCQNGAVCQDGIDGYSCFCVPGYQ-GRHCD-LEVDECASD--PCKNEATCLNEI 205
Query: 253 GSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
G + C C Y+ G NC ++DEC PC +C + G Y C C G+ +
Sbjct: 206 GRYTCICPHNYS----GVNCELEIDEC--WSQPC--LNGATCQDALGAYFCDCAPGF--L 255
Query: 312 GRRC-VDRDECKELPYVCAGGECRNFNGGYVCECP----AGWRFDKTAAVCVDE---RKE 363
G C ++ DEC P + GG C + Y C C G + +C +
Sbjct: 256 GDHCELNTDECASQPCL-HGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNA 314
Query: 364 LCYDEWEAGRCH-----RARPLQLARPEC----C-----CSEGAAWGRYCERCPAPDS-- 407
C D + CH ++ EC C C E ++ +Y P S
Sbjct: 315 TCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFS 374
Query: 408 ----AEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAP- 461
+ ++ ICQ G + +D++EC P C GG C N G++ C CP +
Sbjct: 375 YHEASGYVCICQPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHCPFDNLSRTF 432
Query: 462 -DGLSCVDADECALDPRICGNGTC----SNTRGGYECQCSPGFT 500
G C D + NGTC + + G+ C C G+T
Sbjct: 433 YGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYT 476
Score = 132 bits (319), Expect = 5e-30
Identities = 112/364 (30%), Positives = 157/364 (43%), Gaps = 45/364 (12%)
Query: 8 QSCAGAVGVP-QTKYLCCCSVGHAWGAPCE----ACPPRGSPAHTALCGEKP--GEYINP 60
Q A V P + +LC C G++ G CE +C + S H +C + P I P
Sbjct: 80 QGSATCVNTPGERSFLCKCPPGYS-GTICETTIGSCG-KNSCQHGGICHQDPIYPVCICP 137
Query: 61 VTNETK--PIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGR 117
+ ID + C+ G C D G+ C C GY+ H +VDEC+
Sbjct: 138 AGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQG---RHCDLEVDECA--S 192
Query: 118 PPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRC 176
PC+ A C+N G + C CP Y S CE ++DEC Q + C++ +G+Y C
Sbjct: 193 DPCKNEATCLNEIGRYTCICPHNY----SGVNCELEIDECWSQPCLNGATCQDALGAYFC 248
Query: 177 ECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNEC 236
+C PG+ L ++ + DEC+ +P G C + Y C+C G + C +
Sbjct: 249 DCAPGF-LGDHCELNTDECA-SQPCLHGGLCVDGENRYSCNCTGSGFTGTH--CETLMPL 304
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGYT-------LTADGRN-CRDVDECDEL--PHPCG 286
N C ++V ++ C C PGYT L N C+ EC EL G
Sbjct: 305 CWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYG 364
Query: 287 R-DGNPSCTNTN--GGYECSCGAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYV 341
R G PS + + GY C C G+ G C D +EC P C GG C N G Y
Sbjct: 365 RITGLPSSFSYHEASGYVCICQPGF--TGIHCEEDVNECSSNP--CQNGGTCENLPGNYT 420
Query: 342 CECP 345
C CP
Sbjct: 421 CHCP 424
Score = 112 bits (270), Expect = 4e-24
Identities = 129/466 (27%), Positives = 180/466 (38%), Gaps = 69/466 (14%)
Query: 204 NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVG--SFRCECAP 261
N TC++ C C D + DC ++ + + C NT G SF C+C P
Sbjct: 42 NSTCKDFSKDNDCSCSDTAN-NLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPP 100
Query: 262 GYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRD 319
GY+ G C + C + + C G C C C AG+ GR C +D D
Sbjct: 101 GYS----GTICETTIGSCGK--NSCQHGG--ICHQDPIYPVCICPAGY--AGRFCEIDHD 150
Query: 320 ECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVDE-RKELCYDEW----EAGR 373
EC P C G C++ GY C C G++ + + VDE + C +E E GR
Sbjct: 151 ECASSP--CQNGAVCQDGIDGYSCFCVPGYQ-GRHCDLEVDECASDPCKNEATCLNEIGR 207
Query: 374 CHRARPLQLARPECCCSEGAAWGRYC---ERCPAPDSAEFMRICQGGMGRPNLTQDLDEC 430
P + C W + C C A F G +G + + DEC
Sbjct: 208 YTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG-DHCELNTDEC 266
Query: 431 RVRPDVCV-GGRCVNTDGSFRCECP-DGYVLAPDGLSCVDADECALDPRICGNGTCSNTR 488
+P C+ GG CV+ + + C C G+ G C N TC ++
Sbjct: 267 ASQP--CLHGGLCVDGENRYSCNCTGSGFT----GTHCETLMPLCWSKPCHNNATCEDSV 320
Query: 489 GGYECQCSPGFTQGP---------DQTCVDVDECAE-------GRAS---CTFRCHNTAG 529
Y C C PG+T C EC E GR + +F H +G
Sbjct: 321 DNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASG 380
Query: 530 SFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQD 588
+ C C G+ G+HC D++EC P CEN+ G+Y C CP + S
Sbjct: 381 -YVCICQPGFT----GIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP--FDNLSRTFY 433
Query: 589 SENACEDI-NECEEQEDLCSGGVCIN--TDG--SFLCDCDAGFEPS 629
C DI C Q+ L + G CI DG F C C +G+ S
Sbjct: 434 GGRDCSDILLGCTHQQCL-NNGTCIPHFQDGQHGFSCLCPSGYTGS 478
Score = 88.6 bits (210), Expect = 8e-17
Identities = 64/216 (29%), Positives = 93/216 (43%), Gaps = 27/216 (12%)
Query: 107 CRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG 165
C ++ C+ PC C ++ ++ C CP G+ S CE ++DEC C HG
Sbjct: 1137 CLQLNVCNSN--PCLHGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECFSNP-CIHG 1189
Query: 166 DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKA 224
+C + + +Y C C+PGYT N D+D C + C NG TC + Y C C F
Sbjct: 1190 NCSDRVAAYHCTCEPGYT-GVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLCFGNFTG 1246
Query: 225 G-PNNDCVDVNEC--REGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECD 279
+ C + + C N G C +C C PG+T G C +D+DEC
Sbjct: 1247 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT----GEWCEKDIDEC- 1301
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
PC G C + ++C C + G RC
Sbjct: 1302 -ASDPCVNGG--LCQDLLNKFQCLCDVAF--AGERC 1332
Score = 72.9 bits (171), Expect = 4e-12
Identities = 65/240 (27%), Positives = 95/240 (39%), Gaps = 28/240 (11%)
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDG 463
P +F++I + L L+ C P C+ GG C + S+ C CP G+ G
Sbjct: 1120 PQEEQFLKISTNSVVTGCL--QLNVCNSNP--CLHGGNCEDIYSSYHCSCPLGW----SG 1171
Query: 464 LSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRASCT 521
C ++ DEC +P C +G CS+ Y C C PG+T C VD+D C + +
Sbjct: 1172 KHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEPGYT---GVNCEVDIDNCQSHQCANG 1226
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + + C C + G CR + VC + N+ C E
Sbjct: 1227 ATCISHTNGYSCLCFGNFT----GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1279
Query: 582 RTSA---PQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
P + CE DI+EC + +GG+C + F C CD F D D
Sbjct: 1280 ELKCMCRPGFTGEWCEKDIDEC-ASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
Score = 67.7 bits (158), Expect = 2e-10
Identities = 64/231 (27%), Positives = 92/231 (39%), Gaps = 43/231 (18%)
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG 330
C ++ C+ +PC GN C + Y CSC GW G+ C ++ DEC P C
Sbjct: 1137 CLQLNVCNS--NPCLHGGN--CEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIH 1188
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC-HRARPLQLARPECCC 389
G C + Y C C G+ T C E+ D ++ +C + A + C
Sbjct: 1189 GNCSDRVAAYHCTCEPGY----TGVNC-----EVDIDNCQSHQCANGATCISHTNGYSCL 1239
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
G G++C + P + +C G + NLT C GG C
Sbjct: 1240 CFGNFTGKFCRQSRLPST-----VC--GNEKTNLT-----C------YNGGNCTEFQTEL 1281
Query: 450 RCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGF 499
+C C G+ G C D DECA DP + G G C + ++C C F
Sbjct: 1282 KCMCRPGFT----GEWCEKDIDECASDPCVNG-GLCQDLLNKFQCLCDVAF 1327
Score = 67.7 bits (158), Expect = 2e-10
Identities = 45/159 (28%), Positives = 66/159 (41%), Gaps = 13/159 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P C G C D + C C+ GY N D+D C C A C+
Sbjct: 1178 IDECFSNP--CIHGNCSDRVAAYHCTCEPGYTGVNCE---VDIDNCQ--SHQCANGATCI 1230
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQR---IC-DHGDCRNTIGSYRCECKPGYT 183
+ + C C + CG+++ C + G+C +C C+PG+T
Sbjct: 1231 SHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1290
Query: 184 LRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
E +D+DEC+ P G C++L + C CD F
Sbjct: 1291 -GEWCEKDIDECASD-PCVNGGLCQDLLNKFQCLCDVAF 1327
Score = 66.9 bits (156), Expect = 3e-10
Identities = 43/120 (35%), Positives = 55/120 (45%), Gaps = 16/120 (13%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D DECA+ P +C G + C C PGY+ G C +VDECA P + C N
Sbjct: 148 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQ--GRHCDLEVDECASDPCKNEATCLNEI 205
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
G Y C+C Y G NC ++DEC C + G+Y C C G+ GD C
Sbjct: 206 GRYTCICPHNY----SGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGF--LGDHC 259
Score = 66.9 bits (156), Expect = 3e-10
Identities = 62/234 (26%), Positives = 90/234 (38%), Gaps = 35/234 (14%)
Query: 59 NPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRP 118
N V ++ C+ P L G C D + + C C G+ + H ++DEC + P
Sbjct: 1131 NSVVTGCLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGW---SGKHCELNIDEC-FSNP 1185
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCE 177
G C + A+ C C PGY CE D+D C + + C + Y C
Sbjct: 1186 CIHG--NCSDRVAAYHCTCEPGYTGV----NCEVDIDNCQSHQCANGATCISHTNGYSCL 1239
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRN----------GTCENLPGAYLCHCDDGFKAGPN 227
C +T CR + P VC N G C C C GF G
Sbjct: 1240 CFGNFT--GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF-TGEW 1293
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDEL 281
+ D++EC V G C++ + F+C C + G C +VD D+L
Sbjct: 1294 CE-KDIDECASDPCV-NGGLCQDLLNKFQCLCDVAFA----GERC-EVDLADDL 1340
Score = 54.4 bits (125), Expect = 2e-06
Identities = 68/243 (27%), Positives = 89/243 (36%), Gaps = 47/243 (19%)
Query: 9 SCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPR--GSPA-HTALCGEKPGEYINPVTNET 65
+C A+G Y C C+ G G CE P H LC + Y T
Sbjct: 238 TCQDALGA----YFCDCAPGFL-GDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSG 292
Query: 66 KPIDECDIMPQLC--KP----GTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRP 118
C+ + LC KP TC D+ + C C GY T C D++EC+
Sbjct: 293 FTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY----TGAQCEIDLNECNSN-- 346
Query: 119 PCRGMAQCVNL------------PGAFE--------CRCPPGYRLTPSLDECEDVDECGD 158
PC+ +CV L P +F C C PG+ + EDV+EC
Sbjct: 347 PCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFT---GIHCEEDVNECSS 403
Query: 159 QRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHC 218
+ G C N G+Y C C P L D CS C + C N G + H
Sbjct: 404 NPCQNGGTCENLPGNYTCHC-PFDNLSRTFYGGRD-CSDILLGCTHQQCLN-NGTCIPHF 460
Query: 219 DDG 221
DG
Sbjct: 461 QDG 463
Score = 44.4 bits (100), Expect = 0.002
Identities = 35/113 (30%), Positives = 50/113 (44%), Gaps = 13/113 (11%)
Query: 747 DVDECAAIPGL----C--APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
++DEC + P L C A G + C C PG+ G+ C + DECA +P LC + +
Sbjct: 224 EIDECWSQPCLNGATCQDALGAYFCDCAPGF--LGDHCELNTDECASQPCLHGGLCVDGE 281
Query: 800 GSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
Y C C TG G +C + C C ++ +Y C C GY
Sbjct: 282 NRYSCNC-TGSGF--TGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY 331
Score = 39.9 bits (89), Expect = 0.038
Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 20/100 (20%)
Query: 765 CVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLC------RTGYELDEDGA 817
C+C PG+ G C DV+EC+ P C N G+Y C C RT Y G
Sbjct: 383 CICQPGF--TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFY----GGR 436
Query: 818 NCRDV------DECERDTHTCQQICSNTEGSYECSCEDGY 851
+C D+ +C + TC + + + C C GY
Sbjct: 437 DCSDILLGCTHQQC-LNNGTCIPHFQDGQHGFSCLCPSGY 475
Score = 39.1 bits (87), Expect = 0.066
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
Query: 764 RCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
+C+C PG+ GE C D+DECA P LC + + CLC +
Sbjct: 1282 KCMCRPGF--TGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1327
Score = 38.7 bits (86), Expect = 0.087
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 6/75 (8%)
Query: 778 CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQIC 836
C ++ C P C + SY C C G+ G +C ++DEC + C
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWS----GKHCELNIDECFSNP-CIHGNC 1191
Query: 837 SNTEGSYECSCEDGY 851
S+ +Y C+CE GY
Sbjct: 1192 SDRVAAYHCTCEPGY 1206
Score = 37.1 bits (82), Expect = 0.27
Identities = 32/119 (26%), Positives = 45/119 (37%), Gaps = 20/119 (16%)
Query: 747 DVDECAAIP---GLCAP--GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDG 800
++DEC + P G C+ + C C PGY G C D+D C C +
Sbjct: 1177 NIDECFSNPCIHGNCSDRVAAYHCTCEPGY--TGVNCEVDIDNCQSHQCANGATCISHTN 1234
Query: 801 SYDCLCRTGYELDEDGANCRD------VDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
Y CLC + G CR V E+ TC C+ + +C C G+
Sbjct: 1235 GYSCLCFGNF----TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF 1289
Score = 33.1 bits (72), Expect = 4.3
Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 795 CHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C C+CR G+ G C +D+DEC D +C + ++C C+ +
Sbjct: 1274 CTEFQTELKCMCRPGFT----GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF-- 1327
Query: 854 RGDAC 858
G+ C
Sbjct: 1328 AGERC 1332
Score = 32.7 bits (71), Expect = 5.7
Identities = 19/72 (26%), Positives = 27/72 (37%), Gaps = 8/72 (11%)
Query: 505 QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA 564
Q C + C CH+ F C+CP G C ++ C P CPH
Sbjct: 883 QGCAGDNSCKSNPCHNGGVCHSRWDDFSCSCP----ALTSGKACEEVQWCGFSP--CPHG 936
Query: 565 --CENVVGSYIC 574
C+ V+ + C
Sbjct: 937 AQCQPVLQGFEC 948
>AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 134 bits (323), Expect = 2e-30
Identities = 134/464 (28%), Positives = 191/464 (41%), Gaps = 76/464 (16%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS--WGRPPCRGMAQCVNLPG--AFECRC 137
TC D C C D ++L +D D PC+G A CVN PG +F C+C
Sbjct: 44 TCKDFSKDNDCSCS-----DTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKC 98
Query: 138 PPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYR-CECKPGYTLRENVCR-DVDE 194
PPGY T CE + CG + C HG + Y C C GY R C D DE
Sbjct: 99 PPGYSGT----ICETTIGSCG-KNSCQHGGICHQDPIYPVCICPAGYAGR--FCEIDHDE 151
Query: 195 CSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTV 252
C+ C+NG C++ Y C C G++ G + D ++V+EC C+N C N +
Sbjct: 152 CA--SSPCQNGAVCQDGIDGYSCFCVPGYQ-GRHCD-LEVDECASD--PCKNEATCLNEI 205
Query: 253 GSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
G + C C Y+ G NC ++DEC PC +C + G Y C C G+ +
Sbjct: 206 GRYTCICPHNYS----GVNCELEIDEC--WSQPC--LNGATCQDALGAYFCDCAPGF--L 255
Query: 312 GRRC-VDRDECKELPYVCAGGECRNFNGGYVCECP----AGWRFDKTAAVCVDE---RKE 363
G C ++ DEC P + GG C + Y C C G + +C +
Sbjct: 256 GDHCELNTDECASQPCL-HGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNA 314
Query: 364 LCYDEWEAGRCH-----RARPLQLARPEC----C-----CSEGAAWGRYCERCPAPDS-- 407
C D + CH ++ EC C C E ++ +Y P S
Sbjct: 315 TCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFS 374
Query: 408 ----AEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAP- 461
+ ++ ICQ G + +D++EC P C GG C N G++ C CP +
Sbjct: 375 YHEASGYVCICQPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHCPFDNLSRTF 432
Query: 462 -DGLSCVDADECALDPRICGNGTC----SNTRGGYECQCSPGFT 500
G C D + NGTC + + G+ C C G+T
Sbjct: 433 YGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYT 476
Score = 132 bits (319), Expect = 5e-30
Identities = 112/364 (30%), Positives = 157/364 (43%), Gaps = 45/364 (12%)
Query: 8 QSCAGAVGVP-QTKYLCCCSVGHAWGAPCE----ACPPRGSPAHTALCGEKP--GEYINP 60
Q A V P + +LC C G++ G CE +C + S H +C + P I P
Sbjct: 80 QGSATCVNTPGERSFLCKCPPGYS-GTICETTIGSCG-KNSCQHGGICHQDPIYPVCICP 137
Query: 61 VTNETK--PIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGR 117
+ ID + C+ G C D G+ C C GY+ H +VDEC+
Sbjct: 138 AGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQG---RHCDLEVDECA--S 192
Query: 118 PPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRC 176
PC+ A C+N G + C CP Y S CE ++DEC Q + C++ +G+Y C
Sbjct: 193 DPCKNEATCLNEIGRYTCICPHNY----SGVNCELEIDECWSQPCLNGATCQDALGAYFC 248
Query: 177 ECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNEC 236
+C PG+ L ++ + DEC+ +P G C + Y C+C G + C +
Sbjct: 249 DCAPGF-LGDHCELNTDECA-SQPCLHGGLCVDGENRYSCNCTGSGFTGTH--CETLMPL 304
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGYT-------LTADGRN-CRDVDECDEL--PHPCG 286
N C ++V ++ C C PGYT L N C+ EC EL G
Sbjct: 305 CWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYG 364
Query: 287 R-DGNPSCTNTN--GGYECSCGAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYV 341
R G PS + + GY C C G+ G C D +EC P C GG C N G Y
Sbjct: 365 RITGLPSSFSYHEASGYVCICQPGF--TGIHCEEDVNECSSNP--CQNGGTCENLPGNYT 420
Query: 342 CECP 345
C CP
Sbjct: 421 CHCP 424
Score = 112 bits (270), Expect = 4e-24
Identities = 129/466 (27%), Positives = 180/466 (38%), Gaps = 69/466 (14%)
Query: 204 NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVG--SFRCECAP 261
N TC++ C C D + DC ++ + + C NT G SF C+C P
Sbjct: 42 NSTCKDFSKDNDCSCSDTAN-NLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPP 100
Query: 262 GYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRD 319
GY+ G C + C + + C G C C C AG+ GR C +D D
Sbjct: 101 GYS----GTICETTIGSCGK--NSCQHGG--ICHQDPIYPVCICPAGY--AGRFCEIDHD 150
Query: 320 ECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVDE-RKELCYDEW----EAGR 373
EC P C G C++ GY C C G++ + + VDE + C +E E GR
Sbjct: 151 ECASSP--CQNGAVCQDGIDGYSCFCVPGYQ-GRHCDLEVDECASDPCKNEATCLNEIGR 207
Query: 374 CHRARPLQLARPECCCSEGAAWGRYC---ERCPAPDSAEFMRICQGGMGRPNLTQDLDEC 430
P + C W + C C A F G +G + + DEC
Sbjct: 208 YTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG-DHCELNTDEC 266
Query: 431 RVRPDVCV-GGRCVNTDGSFRCECP-DGYVLAPDGLSCVDADECALDPRICGNGTCSNTR 488
+P C+ GG CV+ + + C C G+ G C N TC ++
Sbjct: 267 ASQP--CLHGGLCVDGENRYSCNCTGSGFT----GTHCETLMPLCWSKPCHNNATCEDSV 320
Query: 489 GGYECQCSPGFTQGP---------DQTCVDVDECAE-------GRAS---CTFRCHNTAG 529
Y C C PG+T C EC E GR + +F H +G
Sbjct: 321 DNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASG 380
Query: 530 SFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQD 588
+ C C G+ G+HC D++EC P CEN+ G+Y C CP + S
Sbjct: 381 -YVCICQPGFT----GIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP--FDNLSRTFY 433
Query: 589 SENACEDI-NECEEQEDLCSGGVCIN--TDG--SFLCDCDAGFEPS 629
C DI C Q+ L + G CI DG F C C +G+ S
Sbjct: 434 GGRDCSDILLGCTHQQCL-NNGTCIPHFQDGQHGFSCLCPSGYTGS 478
Score = 88.6 bits (210), Expect = 8e-17
Identities = 64/216 (29%), Positives = 93/216 (43%), Gaps = 27/216 (12%)
Query: 107 CRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG 165
C ++ C+ PC C ++ ++ C CP G+ S CE ++DEC C HG
Sbjct: 1137 CLQLNVCNSN--PCLHGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECFSNP-CIHG 1189
Query: 166 DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKA 224
+C + + +Y C C+PGYT N D+D C + C NG TC + Y C C F
Sbjct: 1190 NCSDRVAAYHCTCEPGYT-GVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLCFGNFTG 1246
Query: 225 G-PNNDCVDVNEC--REGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECD 279
+ C + + C N G C +C C PG+T G C +D+DEC
Sbjct: 1247 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT----GEWCEKDIDEC- 1301
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
PC G C + ++C C + G RC
Sbjct: 1302 -ASDPCVNGG--LCQDLLNKFQCLCDVAF--AGERC 1332
Score = 72.9 bits (171), Expect = 4e-12
Identities = 65/240 (27%), Positives = 95/240 (39%), Gaps = 28/240 (11%)
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDG 463
P +F++I + L L+ C P C+ GG C + S+ C CP G+ G
Sbjct: 1120 PQEEQFLKISTNSVVTGCL--QLNVCNSNP--CLHGGNCEDIYSSYHCSCPLGW----SG 1171
Query: 464 LSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRASCT 521
C ++ DEC +P C +G CS+ Y C C PG+T C VD+D C + +
Sbjct: 1172 KHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEPGYT---GVNCEVDIDNCQSHQCANG 1226
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + + C C + G CR + VC + N+ C E
Sbjct: 1227 ATCISHTNGYSCLCFGNFT----GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1279
Query: 582 RTSA---PQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
P + CE DI+EC + +GG+C + F C CD F D D
Sbjct: 1280 ELKCMCRPGFTGEWCEKDIDEC-ASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
Score = 67.7 bits (158), Expect = 2e-10
Identities = 64/231 (27%), Positives = 92/231 (39%), Gaps = 43/231 (18%)
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG 330
C ++ C+ +PC GN C + Y CSC GW G+ C ++ DEC P C
Sbjct: 1137 CLQLNVCNS--NPCLHGGN--CEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIH 1188
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC-HRARPLQLARPECCC 389
G C + Y C C G+ T C E+ D ++ +C + A + C
Sbjct: 1189 GNCSDRVAAYHCTCEPGY----TGVNC-----EVDIDNCQSHQCANGATCISHTNGYSCL 1239
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
G G++C + P + +C G + NLT C GG C
Sbjct: 1240 CFGNFTGKFCRQSRLPST-----VC--GNEKTNLT-----C------YNGGNCTEFQTEL 1281
Query: 450 RCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGF 499
+C C G+ G C D DECA DP + G G C + ++C C F
Sbjct: 1282 KCMCRPGFT----GEWCEKDIDECASDPCVNG-GLCQDLLNKFQCLCDVAF 1327
Score = 67.7 bits (158), Expect = 2e-10
Identities = 45/159 (28%), Positives = 66/159 (41%), Gaps = 13/159 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P C G C D + C C+ GY N D+D C C A C+
Sbjct: 1178 IDECFSNP--CIHGNCSDRVAAYHCTCEPGYTGVNCE---VDIDNCQ--SHQCANGATCI 1230
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQR---IC-DHGDCRNTIGSYRCECKPGYT 183
+ + C C + CG+++ C + G+C +C C+PG+T
Sbjct: 1231 SHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1290
Query: 184 LRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
E +D+DEC+ P G C++L + C CD F
Sbjct: 1291 -GEWCEKDIDECASD-PCVNGGLCQDLLNKFQCLCDVAF 1327
Score = 66.9 bits (156), Expect = 3e-10
Identities = 43/120 (35%), Positives = 55/120 (45%), Gaps = 16/120 (13%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D DECA+ P +C G + C C PGY+ G C +VDECA P + C N
Sbjct: 148 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQ--GRHCDLEVDECASDPCKNEATCLNEI 205
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
G Y C+C Y G NC ++DEC C + G+Y C C G+ GD C
Sbjct: 206 GRYTCICPHNY----SGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGF--LGDHC 259
Score = 66.9 bits (156), Expect = 3e-10
Identities = 62/234 (26%), Positives = 90/234 (38%), Gaps = 35/234 (14%)
Query: 59 NPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRP 118
N V ++ C+ P L G C D + + C C G+ + H ++DEC + P
Sbjct: 1131 NSVVTGCLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGW---SGKHCELNIDEC-FSNP 1185
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCE 177
G C + A+ C C PGY CE D+D C + + C + Y C
Sbjct: 1186 CIHG--NCSDRVAAYHCTCEPGYTGV----NCEVDIDNCQSHQCANGATCISHTNGYSCL 1239
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRN----------GTCENLPGAYLCHCDDGFKAGPN 227
C +T CR + P VC N G C C C GF G
Sbjct: 1240 CFGNFT--GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF-TGEW 1293
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDEL 281
+ D++EC V G C++ + F+C C + G C +VD D+L
Sbjct: 1294 CE-KDIDECASDPCV-NGGLCQDLLNKFQCLCDVAFA----GERC-EVDLADDL 1340
Score = 54.4 bits (125), Expect = 2e-06
Identities = 68/243 (27%), Positives = 89/243 (36%), Gaps = 47/243 (19%)
Query: 9 SCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPR--GSPA-HTALCGEKPGEYINPVTNET 65
+C A+G Y C C+ G G CE P H LC + Y T
Sbjct: 238 TCQDALGA----YFCDCAPGFL-GDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSG 292
Query: 66 KPIDECDIMPQLC--KP----GTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRP 118
C+ + LC KP TC D+ + C C GY T C D++EC+
Sbjct: 293 FTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY----TGAQCEIDLNECNSN-- 346
Query: 119 PCRGMAQCVNL------------PGAFE--------CRCPPGYRLTPSLDECEDVDECGD 158
PC+ +CV L P +F C C PG+ + EDV+EC
Sbjct: 347 PCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFT---GIHCEEDVNECSS 403
Query: 159 QRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHC 218
+ G C N G+Y C C P L D CS C + C N G + H
Sbjct: 404 NPCQNGGTCENLPGNYTCHC-PFDNLSRTFYGGRD-CSDILLGCTHQQCLN-NGTCIPHF 460
Query: 219 DDG 221
DG
Sbjct: 461 QDG 463
Score = 44.4 bits (100), Expect = 0.002
Identities = 35/113 (30%), Positives = 50/113 (44%), Gaps = 13/113 (11%)
Query: 747 DVDECAAIPGL----C--APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
++DEC + P L C A G + C C PG+ G+ C + DECA +P LC + +
Sbjct: 224 EIDECWSQPCLNGATCQDALGAYFCDCAPGF--LGDHCELNTDECASQPCLHGGLCVDGE 281
Query: 800 GSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
Y C C TG G +C + C C ++ +Y C C GY
Sbjct: 282 NRYSCNC-TGSGF--TGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY 331
Score = 39.9 bits (89), Expect = 0.038
Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 20/100 (20%)
Query: 765 CVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLC------RTGYELDEDGA 817
C+C PG+ G C DV+EC+ P C N G+Y C C RT Y G
Sbjct: 383 CICQPGF--TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFY----GGR 436
Query: 818 NCRDV------DECERDTHTCQQICSNTEGSYECSCEDGY 851
+C D+ +C + TC + + + C C GY
Sbjct: 437 DCSDILLGCTHQQC-LNNGTCIPHFQDGQHGFSCLCPSGY 475
Score = 39.1 bits (87), Expect = 0.066
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
Query: 764 RCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
+C+C PG+ GE C D+DECA P LC + + CLC +
Sbjct: 1282 KCMCRPGF--TGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1327
Score = 38.7 bits (86), Expect = 0.087
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 6/75 (8%)
Query: 778 CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQIC 836
C ++ C P C + SY C C G+ G +C ++DEC + C
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWS----GKHCELNIDECFSNP-CIHGNC 1191
Query: 837 SNTEGSYECSCEDGY 851
S+ +Y C+CE GY
Sbjct: 1192 SDRVAAYHCTCEPGY 1206
Score = 37.1 bits (82), Expect = 0.27
Identities = 32/119 (26%), Positives = 45/119 (37%), Gaps = 20/119 (16%)
Query: 747 DVDECAAIP---GLCAP--GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDG 800
++DEC + P G C+ + C C PGY G C D+D C C +
Sbjct: 1177 NIDECFSNPCIHGNCSDRVAAYHCTCEPGY--TGVNCEVDIDNCQSHQCANGATCISHTN 1234
Query: 801 SYDCLCRTGYELDEDGANCRD------VDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
Y CLC + G CR V E+ TC C+ + +C C G+
Sbjct: 1235 GYSCLCFGNF----TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF 1289
Score = 33.1 bits (72), Expect = 4.3
Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 795 CHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C C+CR G+ G C +D+DEC D +C + ++C C+ +
Sbjct: 1274 CTEFQTELKCMCRPGFT----GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF-- 1327
Query: 854 RGDAC 858
G+ C
Sbjct: 1328 AGERC 1332
Score = 32.7 bits (71), Expect = 5.7
Identities = 19/72 (26%), Positives = 27/72 (37%), Gaps = 8/72 (11%)
Query: 505 QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA 564
Q C + C CH+ F C+CP G C ++ C P CPH
Sbjct: 883 QGCAGDNSCKSNPCHNGGVCHSRWDDFSCSCP----ALTSGKACEEVQWCGFSP--CPHG 936
Query: 565 --CENVVGSYIC 574
C+ V+ + C
Sbjct: 937 AQCQPVLQGFEC 948
>AL136322-4|CAI16646.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 134 bits (323), Expect = 2e-30
Identities = 134/464 (28%), Positives = 191/464 (41%), Gaps = 76/464 (16%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS--WGRPPCRGMAQCVNLPG--AFECRC 137
TC D C C D ++L +D D PC+G A CVN PG +F C+C
Sbjct: 44 TCKDFSKDNDCSCS-----DTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKC 98
Query: 138 PPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYR-CECKPGYTLRENVCR-DVDE 194
PPGY T CE + CG + C HG + Y C C GY R C D DE
Sbjct: 99 PPGYSGT----ICETTIGSCG-KNSCQHGGICHQDPIYPVCICPAGYAGR--FCEIDHDE 151
Query: 195 CSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTV 252
C+ C+NG C++ Y C C G++ G + D ++V+EC C+N C N +
Sbjct: 152 CA--SSPCQNGAVCQDGIDGYSCFCVPGYQ-GRHCD-LEVDECASD--PCKNEATCLNEI 205
Query: 253 GSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
G + C C Y+ G NC ++DEC PC +C + G Y C C G+ +
Sbjct: 206 GRYTCICPHNYS----GVNCELEIDEC--WSQPC--LNGATCQDALGAYFCDCAPGF--L 255
Query: 312 GRRC-VDRDECKELPYVCAGGECRNFNGGYVCECP----AGWRFDKTAAVCVDE---RKE 363
G C ++ DEC P + GG C + Y C C G + +C +
Sbjct: 256 GDHCELNTDECASQPCL-HGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNA 314
Query: 364 LCYDEWEAGRCH-----RARPLQLARPEC----C-----CSEGAAWGRYCERCPAPDS-- 407
C D + CH ++ EC C C E ++ +Y P S
Sbjct: 315 TCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFS 374
Query: 408 ----AEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAP- 461
+ ++ ICQ G + +D++EC P C GG C N G++ C CP +
Sbjct: 375 YHEASGYVCICQPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHCPFDNLSRTF 432
Query: 462 -DGLSCVDADECALDPRICGNGTC----SNTRGGYECQCSPGFT 500
G C D + NGTC + + G+ C C G+T
Sbjct: 433 YGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYT 476
Score = 132 bits (319), Expect = 5e-30
Identities = 112/364 (30%), Positives = 157/364 (43%), Gaps = 45/364 (12%)
Query: 8 QSCAGAVGVP-QTKYLCCCSVGHAWGAPCE----ACPPRGSPAHTALCGEKP--GEYINP 60
Q A V P + +LC C G++ G CE +C + S H +C + P I P
Sbjct: 80 QGSATCVNTPGERSFLCKCPPGYS-GTICETTIGSCG-KNSCQHGGICHQDPIYPVCICP 137
Query: 61 VTNETK--PIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGR 117
+ ID + C+ G C D G+ C C GY+ H +VDEC+
Sbjct: 138 AGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQG---RHCDLEVDECA--S 192
Query: 118 PPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRC 176
PC+ A C+N G + C CP Y S CE ++DEC Q + C++ +G+Y C
Sbjct: 193 DPCKNEATCLNEIGRYTCICPHNY----SGVNCELEIDECWSQPCLNGATCQDALGAYFC 248
Query: 177 ECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNEC 236
+C PG+ L ++ + DEC+ +P G C + Y C+C G + C +
Sbjct: 249 DCAPGF-LGDHCELNTDECA-SQPCLHGGLCVDGENRYSCNCTGSGFTGTH--CETLMPL 304
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGYT-------LTADGRN-CRDVDECDEL--PHPCG 286
N C ++V ++ C C PGYT L N C+ EC EL G
Sbjct: 305 CWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYG 364
Query: 287 R-DGNPSCTNTN--GGYECSCGAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYV 341
R G PS + + GY C C G+ G C D +EC P C GG C N G Y
Sbjct: 365 RITGLPSSFSYHEASGYVCICQPGF--TGIHCEEDVNECSSNP--CQNGGTCENLPGNYT 420
Query: 342 CECP 345
C CP
Sbjct: 421 CHCP 424
Score = 112 bits (270), Expect = 4e-24
Identities = 129/466 (27%), Positives = 180/466 (38%), Gaps = 69/466 (14%)
Query: 204 NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVG--SFRCECAP 261
N TC++ C C D + DC ++ + + C NT G SF C+C P
Sbjct: 42 NSTCKDFSKDNDCSCSDTAN-NLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPP 100
Query: 262 GYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRD 319
GY+ G C + C + + C G C C C AG+ GR C +D D
Sbjct: 101 GYS----GTICETTIGSCGK--NSCQHGG--ICHQDPIYPVCICPAGY--AGRFCEIDHD 150
Query: 320 ECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVDE-RKELCYDEW----EAGR 373
EC P C G C++ GY C C G++ + + VDE + C +E E GR
Sbjct: 151 ECASSP--CQNGAVCQDGIDGYSCFCVPGYQ-GRHCDLEVDECASDPCKNEATCLNEIGR 207
Query: 374 CHRARPLQLARPECCCSEGAAWGRYC---ERCPAPDSAEFMRICQGGMGRPNLTQDLDEC 430
P + C W + C C A F G +G + + DEC
Sbjct: 208 YTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG-DHCELNTDEC 266
Query: 431 RVRPDVCV-GGRCVNTDGSFRCECP-DGYVLAPDGLSCVDADECALDPRICGNGTCSNTR 488
+P C+ GG CV+ + + C C G+ G C N TC ++
Sbjct: 267 ASQP--CLHGGLCVDGENRYSCNCTGSGFT----GTHCETLMPLCWSKPCHNNATCEDSV 320
Query: 489 GGYECQCSPGFTQGP---------DQTCVDVDECAE-------GRAS---CTFRCHNTAG 529
Y C C PG+T C EC E GR + +F H +G
Sbjct: 321 DNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASG 380
Query: 530 SFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQD 588
+ C C G+ G+HC D++EC P CEN+ G+Y C CP + S
Sbjct: 381 -YVCICQPGFT----GIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP--FDNLSRTFY 433
Query: 589 SENACEDI-NECEEQEDLCSGGVCIN--TDG--SFLCDCDAGFEPS 629
C DI C Q+ L + G CI DG F C C +G+ S
Sbjct: 434 GGRDCSDILLGCTHQQCL-NNGTCIPHFQDGQHGFSCLCPSGYTGS 478
Score = 88.6 bits (210), Expect = 8e-17
Identities = 64/216 (29%), Positives = 93/216 (43%), Gaps = 27/216 (12%)
Query: 107 CRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG 165
C ++ C+ PC C ++ ++ C CP G+ S CE ++DEC C HG
Sbjct: 1137 CLQLNVCNSN--PCLHGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECFSNP-CIHG 1189
Query: 166 DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKA 224
+C + + +Y C C+PGYT N D+D C + C NG TC + Y C C F
Sbjct: 1190 NCSDRVAAYHCTCEPGYT-GVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLCFGNFTG 1246
Query: 225 G-PNNDCVDVNEC--REGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECD 279
+ C + + C N G C +C C PG+T G C +D+DEC
Sbjct: 1247 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT----GEWCEKDIDEC- 1301
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
PC G C + ++C C + G RC
Sbjct: 1302 -ASDPCVNGG--LCQDLLNKFQCLCDVAF--AGERC 1332
Score = 72.9 bits (171), Expect = 4e-12
Identities = 65/240 (27%), Positives = 95/240 (39%), Gaps = 28/240 (11%)
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDG 463
P +F++I + L L+ C P C+ GG C + S+ C CP G+ G
Sbjct: 1120 PQEEQFLKISTNSVVTGCL--QLNVCNSNP--CLHGGNCEDIYSSYHCSCPLGW----SG 1171
Query: 464 LSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRASCT 521
C ++ DEC +P C +G CS+ Y C C PG+T C VD+D C + +
Sbjct: 1172 KHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEPGYT---GVNCEVDIDNCQSHQCANG 1226
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + + C C + G CR + VC + N+ C E
Sbjct: 1227 ATCISHTNGYSCLCFGNFT----GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1279
Query: 582 RTSA---PQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
P + CE DI+EC + +GG+C + F C CD F D D
Sbjct: 1280 ELKCMCRPGFTGEWCEKDIDEC-ASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
Score = 67.7 bits (158), Expect = 2e-10
Identities = 64/231 (27%), Positives = 92/231 (39%), Gaps = 43/231 (18%)
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG 330
C ++ C+ +PC GN C + Y CSC GW G+ C ++ DEC P C
Sbjct: 1137 CLQLNVCNS--NPCLHGGN--CEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIH 1188
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC-HRARPLQLARPECCC 389
G C + Y C C G+ T C E+ D ++ +C + A + C
Sbjct: 1189 GNCSDRVAAYHCTCEPGY----TGVNC-----EVDIDNCQSHQCANGATCISHTNGYSCL 1239
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
G G++C + P + +C G + NLT C GG C
Sbjct: 1240 CFGNFTGKFCRQSRLPST-----VC--GNEKTNLT-----C------YNGGNCTEFQTEL 1281
Query: 450 RCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGF 499
+C C G+ G C D DECA DP + G G C + ++C C F
Sbjct: 1282 KCMCRPGFT----GEWCEKDIDECASDPCVNG-GLCQDLLNKFQCLCDVAF 1327
Score = 67.7 bits (158), Expect = 2e-10
Identities = 45/159 (28%), Positives = 66/159 (41%), Gaps = 13/159 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P C G C D + C C+ GY N D+D C C A C+
Sbjct: 1178 IDECFSNP--CIHGNCSDRVAAYHCTCEPGYTGVNCE---VDIDNCQ--SHQCANGATCI 1230
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQR---IC-DHGDCRNTIGSYRCECKPGYT 183
+ + C C + CG+++ C + G+C +C C+PG+T
Sbjct: 1231 SHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1290
Query: 184 LRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
E +D+DEC+ P G C++L + C CD F
Sbjct: 1291 -GEWCEKDIDECASD-PCVNGGLCQDLLNKFQCLCDVAF 1327
Score = 66.9 bits (156), Expect = 3e-10
Identities = 43/120 (35%), Positives = 55/120 (45%), Gaps = 16/120 (13%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D DECA+ P +C G + C C PGY+ G C +VDECA P + C N
Sbjct: 148 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQ--GRHCDLEVDECASDPCKNEATCLNEI 205
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
G Y C+C Y G NC ++DEC C + G+Y C C G+ GD C
Sbjct: 206 GRYTCICPHNY----SGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGF--LGDHC 259
Score = 66.9 bits (156), Expect = 3e-10
Identities = 62/234 (26%), Positives = 90/234 (38%), Gaps = 35/234 (14%)
Query: 59 NPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRP 118
N V ++ C+ P L G C D + + C C G+ + H ++DEC + P
Sbjct: 1131 NSVVTGCLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGW---SGKHCELNIDEC-FSNP 1185
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCE 177
G C + A+ C C PGY CE D+D C + + C + Y C
Sbjct: 1186 CIHG--NCSDRVAAYHCTCEPGYTGV----NCEVDIDNCQSHQCANGATCISHTNGYSCL 1239
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRN----------GTCENLPGAYLCHCDDGFKAGPN 227
C +T CR + P VC N G C C C GF G
Sbjct: 1240 CFGNFT--GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF-TGEW 1293
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDEL 281
+ D++EC V G C++ + F+C C + G C +VD D+L
Sbjct: 1294 CE-KDIDECASDPCV-NGGLCQDLLNKFQCLCDVAFA----GERC-EVDLADDL 1340
Score = 54.4 bits (125), Expect = 2e-06
Identities = 68/243 (27%), Positives = 89/243 (36%), Gaps = 47/243 (19%)
Query: 9 SCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPR--GSPA-HTALCGEKPGEYINPVTNET 65
+C A+G Y C C+ G G CE P H LC + Y T
Sbjct: 238 TCQDALGA----YFCDCAPGFL-GDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSG 292
Query: 66 KPIDECDIMPQLC--KP----GTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRP 118
C+ + LC KP TC D+ + C C GY T C D++EC+
Sbjct: 293 FTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY----TGAQCEIDLNECNSN-- 346
Query: 119 PCRGMAQCVNL------------PGAFE--------CRCPPGYRLTPSLDECEDVDECGD 158
PC+ +CV L P +F C C PG+ + EDV+EC
Sbjct: 347 PCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFT---GIHCEEDVNECSS 403
Query: 159 QRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHC 218
+ G C N G+Y C C P L D CS C + C N G + H
Sbjct: 404 NPCQNGGTCENLPGNYTCHC-PFDNLSRTFYGGRD-CSDILLGCTHQQCLN-NGTCIPHF 460
Query: 219 DDG 221
DG
Sbjct: 461 QDG 463
Score = 44.4 bits (100), Expect = 0.002
Identities = 35/113 (30%), Positives = 50/113 (44%), Gaps = 13/113 (11%)
Query: 747 DVDECAAIPGL----C--APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
++DEC + P L C A G + C C PG+ G+ C + DECA +P LC + +
Sbjct: 224 EIDECWSQPCLNGATCQDALGAYFCDCAPGF--LGDHCELNTDECASQPCLHGGLCVDGE 281
Query: 800 GSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
Y C C TG G +C + C C ++ +Y C C GY
Sbjct: 282 NRYSCNC-TGSGF--TGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY 331
Score = 39.9 bits (89), Expect = 0.038
Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 20/100 (20%)
Query: 765 CVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLC------RTGYELDEDGA 817
C+C PG+ G C DV+EC+ P C N G+Y C C RT Y G
Sbjct: 383 CICQPGF--TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFY----GGR 436
Query: 818 NCRDV------DECERDTHTCQQICSNTEGSYECSCEDGY 851
+C D+ +C + TC + + + C C GY
Sbjct: 437 DCSDILLGCTHQQC-LNNGTCIPHFQDGQHGFSCLCPSGY 475
Score = 39.1 bits (87), Expect = 0.066
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
Query: 764 RCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
+C+C PG+ GE C D+DECA P LC + + CLC +
Sbjct: 1282 KCMCRPGF--TGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1327
Score = 38.7 bits (86), Expect = 0.087
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 6/75 (8%)
Query: 778 CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQIC 836
C ++ C P C + SY C C G+ G +C ++DEC + C
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWS----GKHCELNIDECFSNP-CIHGNC 1191
Query: 837 SNTEGSYECSCEDGY 851
S+ +Y C+CE GY
Sbjct: 1192 SDRVAAYHCTCEPGY 1206
Score = 37.1 bits (82), Expect = 0.27
Identities = 32/119 (26%), Positives = 45/119 (37%), Gaps = 20/119 (16%)
Query: 747 DVDECAAIP---GLCAP--GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDG 800
++DEC + P G C+ + C C PGY G C D+D C C +
Sbjct: 1177 NIDECFSNPCIHGNCSDRVAAYHCTCEPGY--TGVNCEVDIDNCQSHQCANGATCISHTN 1234
Query: 801 SYDCLCRTGYELDEDGANCRD------VDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
Y CLC + G CR V E+ TC C+ + +C C G+
Sbjct: 1235 GYSCLCFGNF----TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF 1289
Score = 33.1 bits (72), Expect = 4.3
Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 795 CHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C C+CR G+ G C +D+DEC D +C + ++C C+ +
Sbjct: 1274 CTEFQTELKCMCRPGFT----GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF-- 1327
Query: 854 RGDAC 858
G+ C
Sbjct: 1328 AGERC 1332
Score = 32.7 bits (71), Expect = 5.7
Identities = 19/72 (26%), Positives = 27/72 (37%), Gaps = 8/72 (11%)
Query: 505 QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA 564
Q C + C CH+ F C+CP G C ++ C P CPH
Sbjct: 883 QGCAGDNSCKSNPCHNGGVCHSRWDDFSCSCP----ALTSGKACEEVQWCGFSP--CPHG 936
Query: 565 --CENVVGSYIC 574
C+ V+ + C
Sbjct: 937 AQCQPVLQGFEC 948
>AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein.
Length = 1376
Score = 134 bits (323), Expect = 2e-30
Identities = 134/464 (28%), Positives = 191/464 (41%), Gaps = 76/464 (16%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS--WGRPPCRGMAQCVNLPG--AFECRC 137
TC D C C D ++L +D D PC+G A CVN PG +F C+C
Sbjct: 44 TCKDFSKDNDCSCS-----DTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKC 98
Query: 138 PPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYR-CECKPGYTLRENVCR-DVDE 194
PPGY T CE + CG + C HG + Y C C GY R C D DE
Sbjct: 99 PPGYSGT----ICETTIGSCG-KNSCQHGGICHQDPIYPVCICPAGYAGR--FCEIDHDE 151
Query: 195 CSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTV 252
C+ C+NG C++ Y C C G++ G + D ++V+EC C+N C N +
Sbjct: 152 CA--SSPCQNGAVCQDGIDGYSCFCVPGYQ-GRHCD-LEVDECASD--PCKNEATCLNEI 205
Query: 253 GSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
G + C C Y+ G NC ++DEC PC +C + G Y C C G+ +
Sbjct: 206 GRYTCICPHNYS----GVNCELEIDEC--WSQPC--LNGATCQDALGAYFCDCAPGF--L 255
Query: 312 GRRC-VDRDECKELPYVCAGGECRNFNGGYVCECP----AGWRFDKTAAVCVDE---RKE 363
G C ++ DEC P + GG C + Y C C G + +C +
Sbjct: 256 GDHCELNTDECASQPCL-HGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNA 314
Query: 364 LCYDEWEAGRCH-----RARPLQLARPEC----C-----CSEGAAWGRYCERCPAPDS-- 407
C D + CH ++ EC C C E ++ +Y P S
Sbjct: 315 TCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFS 374
Query: 408 ----AEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAP- 461
+ ++ ICQ G + +D++EC P C GG C N G++ C CP +
Sbjct: 375 YHEASGYVCICQPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHCPFDNLSRTF 432
Query: 462 -DGLSCVDADECALDPRICGNGTC----SNTRGGYECQCSPGFT 500
G C D + NGTC + + G+ C C G+T
Sbjct: 433 YGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYT 476
Score = 132 bits (319), Expect = 5e-30
Identities = 112/364 (30%), Positives = 157/364 (43%), Gaps = 45/364 (12%)
Query: 8 QSCAGAVGVP-QTKYLCCCSVGHAWGAPCE----ACPPRGSPAHTALCGEKP--GEYINP 60
Q A V P + +LC C G++ G CE +C + S H +C + P I P
Sbjct: 80 QGSATCVNTPGERSFLCKCPPGYS-GTICETTIGSCG-KNSCQHGGICHQDPIYPVCICP 137
Query: 61 VTNETK--PIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGR 117
+ ID + C+ G C D G+ C C GY+ H +VDEC+
Sbjct: 138 AGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQG---RHCDLEVDECA--S 192
Query: 118 PPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRC 176
PC+ A C+N G + C CP Y S CE ++DEC Q + C++ +G+Y C
Sbjct: 193 DPCKNEATCLNEIGRYTCICPHNY----SGVNCELEIDECWSQPCLNGATCQDALGAYFC 248
Query: 177 ECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNEC 236
+C PG+ L ++ + DEC+ +P G C + Y C+C G + C +
Sbjct: 249 DCAPGF-LGDHCELNTDECA-SQPCLHGGLCVDGENRYSCNCTGSGFTGTH--CETLMPL 304
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGYT-------LTADGRN-CRDVDECDEL--PHPCG 286
N C ++V ++ C C PGYT L N C+ EC EL G
Sbjct: 305 CWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYG 364
Query: 287 R-DGNPSCTNTN--GGYECSCGAGWKLVGRRC-VDRDECKELPYVCA-GGECRNFNGGYV 341
R G PS + + GY C C G+ G C D +EC P C GG C N G Y
Sbjct: 365 RITGLPSSFSYHEASGYVCICQPGF--TGIHCEEDVNECSSNP--CQNGGTCENLPGNYT 420
Query: 342 CECP 345
C CP
Sbjct: 421 CHCP 424
Score = 112 bits (270), Expect = 4e-24
Identities = 129/466 (27%), Positives = 180/466 (38%), Gaps = 69/466 (14%)
Query: 204 NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVG--SFRCECAP 261
N TC++ C C D + DC ++ + + C NT G SF C+C P
Sbjct: 42 NSTCKDFSKDNDCSCSDTAN-NLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPP 100
Query: 262 GYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRD 319
GY+ G C + C + + C G C C C AG+ GR C +D D
Sbjct: 101 GYS----GTICETTIGSCGK--NSCQHGG--ICHQDPIYPVCICPAGY--AGRFCEIDHD 150
Query: 320 ECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVDE-RKELCYDEW----EAGR 373
EC P C G C++ GY C C G++ + + VDE + C +E E GR
Sbjct: 151 ECASSP--CQNGAVCQDGIDGYSCFCVPGYQ-GRHCDLEVDECASDPCKNEATCLNEIGR 207
Query: 374 CHRARPLQLARPECCCSEGAAWGRYC---ERCPAPDSAEFMRICQGGMGRPNLTQDLDEC 430
P + C W + C C A F G +G + + DEC
Sbjct: 208 YTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG-DHCELNTDEC 266
Query: 431 RVRPDVCV-GGRCVNTDGSFRCECP-DGYVLAPDGLSCVDADECALDPRICGNGTCSNTR 488
+P C+ GG CV+ + + C C G+ G C N TC ++
Sbjct: 267 ASQP--CLHGGLCVDGENRYSCNCTGSGFT----GTHCETLMPLCWSKPCHNNATCEDSV 320
Query: 489 GGYECQCSPGFTQGP---------DQTCVDVDECAE-------GRAS---CTFRCHNTAG 529
Y C C PG+T C EC E GR + +F H +G
Sbjct: 321 DNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASG 380
Query: 530 SFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQD 588
+ C C G+ G+HC D++EC P CEN+ G+Y C CP + S
Sbjct: 381 -YVCICQPGFT----GIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP--FDNLSRTFY 433
Query: 589 SENACEDI-NECEEQEDLCSGGVCIN--TDG--SFLCDCDAGFEPS 629
C DI C Q+ L + G CI DG F C C +G+ S
Sbjct: 434 GGRDCSDILLGCTHQQCL-NNGTCIPHFQDGQHGFSCLCPSGYTGS 478
Score = 88.6 bits (210), Expect = 8e-17
Identities = 64/216 (29%), Positives = 93/216 (43%), Gaps = 27/216 (12%)
Query: 107 CRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG 165
C ++ C+ PC C ++ ++ C CP G+ S CE ++DEC C HG
Sbjct: 1137 CLQLNVCNSN--PCLHGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECFSNP-CIHG 1189
Query: 166 DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKA 224
+C + + +Y C C+PGYT N D+D C + C NG TC + Y C C F
Sbjct: 1190 NCSDRVAAYHCTCEPGYT-GVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLCFGNFTG 1246
Query: 225 G-PNNDCVDVNEC--REGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECD 279
+ C + + C N G C +C C PG+T G C +D+DEC
Sbjct: 1247 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT----GEWCEKDIDEC- 1301
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
PC G C + ++C C + G RC
Sbjct: 1302 -ASDPCVNGG--LCQDLLNKFQCLCDVAF--AGERC 1332
Score = 72.1 bits (169), Expect = 8e-12
Identities = 63/229 (27%), Positives = 93/229 (40%), Gaps = 28/229 (12%)
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDG 463
P +F++I + L L+ C P C+ GG C + S+ C CP G+ G
Sbjct: 1120 PQEEQFLKISTNSVVTGCL--QLNVCNSNP--CLHGGNCEDIYSSYHCSCPLGW----SG 1171
Query: 464 LSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRASCT 521
C ++ DEC +P C +G CS+ Y C C PG+T C VD+D C + +
Sbjct: 1172 KHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEPGYT---GVNCEVDIDNCQSHQCANG 1226
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + + C C + G CR + VC + N+ C E
Sbjct: 1227 ATCISHTNGYSCLCFGNFT----GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1279
Query: 582 RTSA---PQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
P + CE DI+EC + +GG+C + F C CD F
Sbjct: 1280 ELKCMCRPGFTGEWCEKDIDEC-ASDPCVNGGLCQDLLNKFQCLCDVAF 1327
Score = 68.1 bits (159), Expect = 1e-10
Identities = 50/171 (29%), Positives = 73/171 (42%), Gaps = 15/171 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P C G C D + C C+ GY N D+D C C A C+
Sbjct: 1178 IDECFSNP--CIHGNCSDRVAAYHCTCEPGYTGVNCE---VDIDNCQ--SHQCANGATCI 1230
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQR---IC-DHGDCRNTIGSYRCECKPGYT 183
+ + C C + CG+++ C + G+C +C C+PG+T
Sbjct: 1231 SHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1290
Query: 184 LRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVN 234
E +D+DEC+ P G C++L + C CD F AG + VDV+
Sbjct: 1291 -GEWCEKDIDECASD-PCVNGGLCQDLLNKFQCLCDVAF-AGERCE-VDVS 1337
Score = 67.7 bits (158), Expect = 2e-10
Identities = 64/231 (27%), Positives = 92/231 (39%), Gaps = 43/231 (18%)
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG 330
C ++ C+ +PC GN C + Y CSC GW G+ C ++ DEC P C
Sbjct: 1137 CLQLNVCNS--NPCLHGGN--CEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIH 1188
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC-HRARPLQLARPECCC 389
G C + Y C C G+ T C E+ D ++ +C + A + C
Sbjct: 1189 GNCSDRVAAYHCTCEPGY----TGVNC-----EVDIDNCQSHQCANGATCISHTNGYSCL 1239
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
G G++C + P + +C G + NLT C GG C
Sbjct: 1240 CFGNFTGKFCRQSRLPST-----VC--GNEKTNLT-----C------YNGGNCTEFQTEL 1281
Query: 450 RCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGF 499
+C C G+ G C D DECA DP + G G C + ++C C F
Sbjct: 1282 KCMCRPGFT----GEWCEKDIDECASDPCVNG-GLCQDLLNKFQCLCDVAF 1327
Score = 66.9 bits (156), Expect = 3e-10
Identities = 43/120 (35%), Positives = 55/120 (45%), Gaps = 16/120 (13%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D DECA+ P +C G + C C PGY+ G C +VDECA P + C N
Sbjct: 148 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQ--GRHCDLEVDECASDPCKNEATCLNEI 205
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
G Y C+C Y G NC ++DEC C + G+Y C C G+ GD C
Sbjct: 206 GRYTCICPHNY----SGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGF--LGDHC 259
Score = 64.1 bits (149), Expect = 2e-09
Identities = 56/212 (26%), Positives = 81/212 (38%), Gaps = 30/212 (14%)
Query: 59 NPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRP 118
N V ++ C+ P L G C D + + C C G+ + H ++DEC + P
Sbjct: 1131 NSVVTGCLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGW---SGKHCELNIDEC-FSNP 1185
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCE 177
G C + A+ C C PGY CE D+D C + + C + Y C
Sbjct: 1186 CIHG--NCSDRVAAYHCTCEPGYTGV----NCEVDIDNCQSHQCANGATCISHTNGYSCL 1239
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRN----------GTCENLPGAYLCHCDDGFKAGPN 227
C +T CR + P VC N G C C C GF G
Sbjct: 1240 CFGNFT--GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF-TGEW 1293
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCEC 259
+ D++EC V G C++ + F+C C
Sbjct: 1294 CE-KDIDECASDPCV-NGGLCQDLLNKFQCLC 1323
Score = 54.4 bits (125), Expect = 2e-06
Identities = 68/243 (27%), Positives = 89/243 (36%), Gaps = 47/243 (19%)
Query: 9 SCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPR--GSPA-HTALCGEKPGEYINPVTNET 65
+C A+G Y C C+ G G CE P H LC + Y T
Sbjct: 238 TCQDALGA----YFCDCAPGFL-GDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSG 292
Query: 66 KPIDECDIMPQLC--KP----GTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRP 118
C+ + LC KP TC D+ + C C GY T C D++EC+
Sbjct: 293 FTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY----TGAQCEIDLNECNSN-- 346
Query: 119 PCRGMAQCVNL------------PGAFE--------CRCPPGYRLTPSLDECEDVDECGD 158
PC+ +CV L P +F C C PG+ + EDV+EC
Sbjct: 347 PCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFT---GIHCEEDVNECSS 403
Query: 159 QRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHC 218
+ G C N G+Y C C P L D CS C + C N G + H
Sbjct: 404 NPCQNGGTCENLPGNYTCHC-PFDNLSRTFYGGRD-CSDILLGCTHQQCLN-NGTCIPHF 460
Query: 219 DDG 221
DG
Sbjct: 461 QDG 463
Score = 48.8 bits (111), Expect = 8e-05
Identities = 42/181 (23%), Positives = 67/181 (37%), Gaps = 11/181 (6%)
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDS-AEFMRICQGGMGRPNL 423
C D + + C + PL + C + + C D A + C+ G N
Sbjct: 1154 CEDIYSSYHC--SCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNC 1211
Query: 424 TQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPR--ICGN 481
D+D C+ G C++ + C C + S + + C + C N
Sbjct: 1212 EVDIDNCQSH-QCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYN 1270
Query: 482 G-TCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRASCTFRCHNTAGSFRCTCPYGY 539
G C+ + +C C PGFT + C D+DECA C + F+C C +
Sbjct: 1271 GGNCTEFQTELKCMCRPGFT---GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1327
Query: 540 A 540
A
Sbjct: 1328 A 1328
Score = 44.4 bits (100), Expect = 0.002
Identities = 35/113 (30%), Positives = 50/113 (44%), Gaps = 13/113 (11%)
Query: 747 DVDECAAIPGL----C--APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
++DEC + P L C A G + C C PG+ G+ C + DECA +P LC + +
Sbjct: 224 EIDECWSQPCLNGATCQDALGAYFCDCAPGF--LGDHCELNTDECASQPCLHGGLCVDGE 281
Query: 800 GSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
Y C C TG G +C + C C ++ +Y C C GY
Sbjct: 282 NRYSCNC-TGSGF--TGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY 331
Score = 39.9 bits (89), Expect = 0.038
Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 20/100 (20%)
Query: 765 CVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLC------RTGYELDEDGA 817
C+C PG+ G C DV+EC+ P C N G+Y C C RT Y G
Sbjct: 383 CICQPGF--TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFY----GGR 436
Query: 818 NCRDV------DECERDTHTCQQICSNTEGSYECSCEDGY 851
+C D+ +C + TC + + + C C GY
Sbjct: 437 DCSDILLGCTHQQC-LNNGTCIPHFQDGQHGFSCLCPSGY 475
Score = 39.1 bits (87), Expect = 0.066
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
Query: 764 RCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
+C+C PG+ GE C D+DECA P LC + + CLC +
Sbjct: 1282 KCMCRPGF--TGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1327
Score = 38.7 bits (86), Expect = 0.087
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 6/75 (8%)
Query: 778 CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQIC 836
C ++ C P C + SY C C G+ G +C ++DEC + C
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWS----GKHCELNIDECFSNP-CIHGNC 1191
Query: 837 SNTEGSYECSCEDGY 851
S+ +Y C+CE GY
Sbjct: 1192 SDRVAAYHCTCEPGY 1206
Score = 37.1 bits (82), Expect = 0.27
Identities = 32/119 (26%), Positives = 45/119 (37%), Gaps = 20/119 (16%)
Query: 747 DVDECAAIP---GLCAP--GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDG 800
++DEC + P G C+ + C C PGY G C D+D C C +
Sbjct: 1177 NIDECFSNPCIHGNCSDRVAAYHCTCEPGY--TGVNCEVDIDNCQSHQCANGATCISHTN 1234
Query: 801 SYDCLCRTGYELDEDGANCRD------VDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
Y CLC + G CR V E+ TC C+ + +C C G+
Sbjct: 1235 GYSCLCFGNF----TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF 1289
Score = 33.1 bits (72), Expect = 4.3
Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 795 CHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C C+CR G+ G C +D+DEC D +C + ++C C+ +
Sbjct: 1274 CTEFQTELKCMCRPGFT----GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF-- 1327
Query: 854 RGDAC 858
G+ C
Sbjct: 1328 AGERC 1332
Score = 32.7 bits (71), Expect = 5.7
Identities = 19/72 (26%), Positives = 27/72 (37%), Gaps = 8/72 (11%)
Query: 505 QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA 564
Q C + C CH+ F C+CP G C ++ C P CPH
Sbjct: 883 QGCAGDNSCKSNPCHNGGVCHSRWDDFSCSCP----ALTSGKACEEVQWCGFSP--CPHG 936
Query: 565 --CENVVGSYIC 574
C+ V+ + C
Sbjct: 937 AQCQPVLQGFEC 948
>AK075489-1|BAC11648.1| 451|Homo sapiens rase 7. protein.
Length = 451
Score = 132 bits (320), Expect = 4e-30
Identities = 67/195 (34%), Positives = 88/195 (45%), Gaps = 7/195 (3%)
Query: 442 CVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQ 501
C+N GS+ C C GY+L D +C D CA++ C C N G + CQC G+
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNC-EQLCVNVPGSFVCQCYSGYAL 311
Query: 502 GPD-QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRV 560
D + CV VD CA C C N GS+ C C G+A+ D C ID C
Sbjct: 312 AEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHG 371
Query: 561 CPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLC 620
C H C N SY C C +G+ T P + C IN C + C C+N + S+ C
Sbjct: 372 CQHECVNTDDSYSCHCLKGF--TLNP--DKKTCRRINYCALNKPGCE-HECVNMEESYYC 426
Query: 621 DCDAGFEPSEDGTDC 635
C G+ +G C
Sbjct: 427 RCHRGYTLDPNGKTC 441
Score = 128 bits (310), Expect = 6e-29
Identities = 65/165 (39%), Positives = 79/165 (47%), Gaps = 9/165 (5%)
Query: 423 LTQDLDECRVRPDVCV------GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDP 476
L D CR++ D+C CVN GSF C+C GY LA DG CV D CA +
Sbjct: 270 LNSDQTTCRIQ-DLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASEN 328
Query: 477 RICGNGTCSNTRGGYECQCSPGFTQGPDQ-TCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
C + C N G Y CQC GF PD+ TC +D CA C C NT S+ C C
Sbjct: 329 HGCEH-ECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHC 387
Query: 536 PYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGY 580
G+ + D CR I+ C C H C N+ SY C+C GY
Sbjct: 388 LKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGY 432
Score = 124 bits (298), Expect = 2e-27
Identities = 65/194 (33%), Positives = 91/194 (46%), Gaps = 9/194 (4%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
C + P + C C GY ++ CR D C+ C + CVN+PG+F C+C GY
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQL--CVNVPGSFVCQCYSGYA 310
Query: 143 LTPSLDECEDVDECGDQRI-CDHGDCRNTIGSYRCECKPGYTLR--ENVCRDVDECSRPR 199
L C VD C + C+H +C N GSY C+C G+ L + C +D C+
Sbjct: 311 LAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSN 369
Query: 200 PVCRNGTCENLPGAYLCHCDDGFKAGPN-NDCVDVNECREGGMVCRNGRCRNTVGSFRCE 258
C++ C N +Y CHC GF P+ C +N C C + C N S+ C
Sbjct: 370 HGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCR 427
Query: 259 CAPGYTLTADGRNC 272
C GYTL +G+ C
Sbjct: 428 CHRGYTLDPNGKTC 441
Score = 120 bits (289), Expect = 2e-26
Identities = 63/189 (33%), Positives = 88/189 (46%), Gaps = 11/189 (5%)
Query: 126 CVNLPGAFECRCPPGYRLTPSLDECEDVDECG-DQRICDHGDCRNTIGSYRCECKPGYTL 184
C+N+PG++ CRC GY L C D C + C+ C N GS+ C+C GY L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQL-CVNVPGSFVCQCYSGYAL 311
Query: 185 RENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGGM 241
E+ C VD C+ C + C N G+YLC C +GF P+ C ++ C
Sbjct: 312 AEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNH 370
Query: 242 VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
C++ C NT S+ C C G+TL D + CR ++ C C + C N Y
Sbjct: 371 GCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHE----CVNMEESYY 425
Query: 302 CSCGAGWKL 310
C C G+ L
Sbjct: 426 CRCHRGYTL 434
Score = 118 bits (284), Expect = 9e-26
Identities = 66/173 (38%), Positives = 80/173 (46%), Gaps = 10/173 (5%)
Query: 484 CSNTRGGYECQCSPGFTQGPDQT-CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVA 542
C N G Y C+C G+ DQT C D CA +C C N GSF C C GYA+A
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312
Query: 543 ADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQ 602
DG C +D C E C H C N GSY+C+C EG+ A + C I+ C
Sbjct: 313 EDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGF----ALNPDKKTCTKIDYCASS 368
Query: 603 EDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPE 655
C C+NTD S+ C C GF + D C RR C +L CE E
Sbjct: 369 NHGCQ-HECVNTDDSYSCHCLKGFTLNPDKKTC--RRINYC--ALNKPGCEHE 416
Score = 113 bits (272), Expect = 3e-24
Identities = 66/207 (31%), Positives = 87/207 (42%), Gaps = 19/207 (9%)
Query: 162 CDHGDCRNTIGSYRCECKPGYTLR--ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCD 219
C H C N GSY C CK GY L + CR D C+ C C N+PG+++C C
Sbjct: 249 CAHF-CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCY 306
Query: 220 DGFK-AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDEC 278
G+ A CV V+ C C + C N GS+ C+C G+ L D + C +D C
Sbjct: 307 SGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTCTKIDYC 365
Query: 279 DELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGG-----EC 333
H C + C NT+ Y C C G+ L D+ C+ + Y EC
Sbjct: 366 ASSNHGCQHE----CVNTDDSYSCHCLKGFTLNP----DKKTCRRINYCALNKPGCEHEC 417
Query: 334 RNFNGGYVCECPAGWRFDKTAAVCVDE 360
N Y C C G+ D C E
Sbjct: 418 VNMEESYYCRCHRGYTLDPNGKTCSRE 444
Score = 89.8 bits (213), Expect = 4e-17
Identities = 40/99 (40%), Positives = 51/99 (51%), Gaps = 2/99 (2%)
Query: 760 PGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG + C C GY + C D CA+ C+QLC N GS+ C C +GY L EDG
Sbjct: 257 PGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGK 316
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C VD C + H C+ C N +GSY C C +G+ D
Sbjct: 317 RCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPD 355
Score = 89.0 bits (211), Expect = 6e-17
Identities = 41/99 (41%), Positives = 48/99 (48%), Gaps = 2/99 (2%)
Query: 760 PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG F C C GY A G+ C VD CA C+ C N DGSY C C G+ L+ D
Sbjct: 298 PGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKK 357
Query: 818 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
C +D C H CQ C NT+ SY C C G+ D
Sbjct: 358 TCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPD 396
Score = 88.6 bits (210), Expect = 8e-17
Identities = 42/123 (34%), Positives = 57/123 (46%), Gaps = 5/123 (4%)
Query: 513 CAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSY 572
C+ +C C N GS+ C C GY + +D CR D C E C C NV GS+
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSF 301
Query: 573 ICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDG 632
+C+C GY A + C ++ C + C C+N DGS+LC C GF + D
Sbjct: 302 VCQCYSGY----ALAEDGKRCVAVDYCASENHGCE-HECVNADGSYLCQCHEGFALNPDK 356
Query: 633 TDC 635
C
Sbjct: 357 KTC 359
Score = 78.6 bits (185), Expect = 9e-14
Identities = 37/104 (35%), Positives = 48/104 (46%), Gaps = 4/104 (3%)
Query: 759 APGRFRCVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 816
A G + C C G+ P + C +D CA C C NTD SY C C G+ L+ D
Sbjct: 338 ADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDK 397
Query: 817 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDAC 858
CR ++ C + C+ C N E SY C C GY + G C
Sbjct: 398 KTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTC 441
Score = 72.5 bits (170), Expect = 6e-12
Identities = 31/78 (39%), Positives = 39/78 (50%), Gaps = 2/78 (2%)
Query: 784 CAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSY 843
C+ C C N GSY C C+ GY L+ D CR D C + H C+Q+C N GS+
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSF 301
Query: 844 ECSCEDGY--EKRGDACV 859
C C GY + G CV
Sbjct: 302 VCQCYSGYALAEDGKRCV 319
Score = 66.5 bits (155), Expect = 4e-10
Identities = 51/206 (24%), Positives = 84/206 (40%), Gaps = 21/206 (10%)
Query: 7 DQSCAG-AVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPA---HTA--LCGEKPGEYI-- 58
+ +CA + +P + Y+C C G+ + C + A H LC PG ++
Sbjct: 246 EHNCAHFCINIPGS-YVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQ 304
Query: 59 ----NPVTNETK---PIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVD 111
+ + K +D C C+ C + + C C G+ + C +D
Sbjct: 305 CYSGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTCTKID 363
Query: 112 ECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECG-DQRICDHGDCRNT 170
C+ C+ +CVN ++ C C G+ L P C ++ C ++ C+H +C N
Sbjct: 364 YCASSNHGCQH--ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-ECVNM 420
Query: 171 IGSYRCECKPGYTLRENVCRDVDECS 196
SY C C GYTL N EC+
Sbjct: 421 EESYYCRCHRGYTLDPNGKTCSRECT 446
>BC038587-1|AAH38587.1| 553|Homo sapiens EGF-like-domain, multiple
6 protein.
Length = 553
Score = 131 bits (316), Expect = 1e-29
Identities = 75/196 (38%), Positives = 93/196 (47%), Gaps = 17/196 (8%)
Query: 437 CVGGRCVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGNGTCSNTRGGYECQC 495
C G CV G +C C GY G +C D +EC + PR C + C NT G Y+C C
Sbjct: 69 CKFGECV---GPNKCRCFPGYT----GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFC 120
Query: 496 SPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPY-GYAVAADGVHCRDIDEC 554
G PD TCV+ CA +C + C +T +C CP G +A +G C DIDEC
Sbjct: 121 LSGHMLMPDATCVNSRTCA--MINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDEC 178
Query: 555 VQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-C 611
+CP+ C N GSY CKC G+ C DINEC CS C
Sbjct: 179 ASGKVICPYNRRCVNTFGSYYCKCHIGFELQYI--SGRYDCIDINECTMDSHTCSHHANC 236
Query: 612 INTDGSFLCDCDAGFE 627
NT GSF C C G++
Sbjct: 237 FNTQGSFKCKCKQGYK 252
Score = 130 bits (314), Expect = 2e-29
Identities = 87/244 (35%), Positives = 122/244 (50%), Gaps = 29/244 (11%)
Query: 79 KPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCP 138
+PG CH G + C +G+ N+ +C E P C+ +CV G +CRC
Sbjct: 37 QPGVCH---YGTKLACCYGWRR-NSKGVCEATCE-----PGCK-FGECV---GPNKCRCF 83
Query: 139 PGYRLTPSLDECEDVDECGDQ-RICDHGDCRNTIGSYRCECKPGYTLRENV-CRDVDECS 196
PGY +DV+ECG + R C H C NT GSY+C C G+ L + C + C+
Sbjct: 84 PGYTGKTC---SQDVNECGMKPRPCQHR-CVNTHGSYKCFCLSGHMLMPDATCVNSRTCA 139
Query: 197 RPRPVCRNGTCENLPGAYLCHC-DDGFKAGPNN-DCVDVNECREGGMVCR-NGRCRNTVG 253
C+ +CE+ C C G + PN DC+D++EC G ++C N RC NT G
Sbjct: 140 MIN--CQY-SCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFG 196
Query: 254 SFRCECAPGYTLT-ADGR-NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
S+ C+C G+ L GR +C D++EC H C N C NT G ++C C G+K
Sbjct: 197 SYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHAN--CFNTQGSFKCKCKQGYKGN 254
Query: 312 GRRC 315
G RC
Sbjct: 255 GLRC 258
Score = 130 bits (313), Expect = 3e-29
Identities = 73/204 (35%), Positives = 106/204 (51%), Gaps = 21/204 (10%)
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNT 445
E C G +G C P+ C G +QD++EC ++P C RCVNT
Sbjct: 62 EATCEPGCKFGE----CVGPNKCR----CFPGYTGKTCSQDVNECGMKPRPCQH-RCVNT 112
Query: 446 DGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQC-SPGFTQGPD 504
GS++C C G++L PD +CV++ CA+ I +C +T G +C C S G P+
Sbjct: 113 HGSYKCFCLSGHMLMPDA-TCVNSRTCAM---INCQYSCEDTEEGPQCLCPSSGLRLAPN 168
Query: 505 -QTCVDVDECAEGRASCTF--RCHNTAGSFRCTCPYGYAV--AADGVHCRDIDECVQEPR 559
+ C+D+DECA G+ C + RC NT GS+ C C G+ + + C DI+EC +
Sbjct: 169 GRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSH 228
Query: 560 VCPH--ACENVVGSYICKCPEGYR 581
C H C N GS+ CKC +GY+
Sbjct: 229 TCSHHANCFNTQGSFKCKCKQGYK 252
Score = 109 bits (263), Expect = 3e-23
Identities = 75/220 (34%), Positives = 105/220 (47%), Gaps = 23/220 (10%)
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECS 196
C G+R S CE E G C G+C +G +C C PGYT + +DV+EC
Sbjct: 49 CCYGWRRN-SKGVCEATCEPG----CKFGEC---VGPNKCRCFPGYT-GKTCSQDVNECG 99
Query: 197 -RPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSF 255
+PRP C++ C N G+Y C C G P+ CV+ C M+ C +T
Sbjct: 100 MKPRP-CQH-RCVNTHGSYKCFCLSGHMLMPDATCVNSRTC---AMINCQYSCEDTEEGP 154
Query: 256 RCEC-APGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--- 311
+C C + G L +GR+C D+DEC C N C NT G Y C C G++L
Sbjct: 155 QCLCPSSGLRLAPNGRDCLDIDECASGKVICPY--NRRCVNTFGSYYCKCHIGFELQYIS 212
Query: 312 GRR-CVDRDECKELPYVCAG-GECRNFNGGYVCECPAGWR 349
GR C+D +EC + C+ C N G + C+C G++
Sbjct: 213 GRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYK 252
Score = 86.6 bits (205), Expect = 3e-16
Identities = 57/163 (34%), Positives = 76/163 (46%), Gaps = 16/163 (9%)
Query: 479 CGNGTCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRASCTFRCHNTAGSFRCTCPY 537
C G C G +C+C PG+T +TC DV+EC C RC NT GS++C C
Sbjct: 69 CKFGECV---GPNKCRCFPGYT---GKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLS 122
Query: 538 GYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDIN 597
G+ + D C + C C ++CE+ C CP R AP + C DI+
Sbjct: 123 GHMLMPDAT-CVNSRTCAMIN--CQYSCEDTEEGPQCLCPSSGLRL-APNGRD--CLDID 176
Query: 598 ECEEQEDLCS-GGVCINTDGSFLCDCDAGFEPS--EDGTDCID 637
EC + +C C+NT GS+ C C GFE DCID
Sbjct: 177 ECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCID 219
Score = 84.6 bits (200), Expect = 1e-15
Identities = 43/104 (41%), Positives = 58/104 (55%), Gaps = 9/104 (8%)
Query: 764 RCVC-GPGYR--PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGA- 817
+C+C G R P G C D+DECA C ++ C NT GSY C C G+EL
Sbjct: 155 QCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGR 214
Query: 818 -NCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDAC 858
+C D++EC D+HTC C NT+GS++C C+ GY+ G C
Sbjct: 215 YDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRC 258
Score = 81.4 bits (192), Expect = 1e-14
Identities = 47/141 (33%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Query: 82 TCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
+C DT G QC C G C D+DEC+ G+ C +CVN G++ C+C G
Sbjct: 146 SCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIG 205
Query: 141 YRL--TPSLDECEDVDECG-DQRICD-HGDCRNTIGSYRCECKPGYTLRENVCRDVDECS 196
+ L +C D++EC D C H +C NT GS++C+CK GY C + E S
Sbjct: 206 FELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENS 265
Query: 197 RPRPVCRNGTCENLPGAYLCH 217
+ GT ++ L H
Sbjct: 266 VKEVLRAPGTIKDRIKKLLAH 286
Score = 71.3 bits (167), Expect = 1e-11
Identities = 38/93 (40%), Positives = 49/93 (52%), Gaps = 7/93 (7%)
Query: 756 GLCAPGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 814
G C G +C C PGY G+ C+ DV+EC ++P PC C NT GSY C C +G+ L
Sbjct: 72 GECV-GPNKCRCFPGY--TGKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMP 128
Query: 815 DGANCRDVDECERDTHTCQQICSNTEGSYECSC 847
D A C + C CQ C +TE +C C
Sbjct: 129 D-ATCVNSRTCA--MINCQYSCEDTEEGPQCLC 158
Score = 52.0 bits (119), Expect = 9e-06
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 55 GEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTS--HLCRDVD 111
G + P + IDEC +C C +T + C C G+E S + C D++
Sbjct: 162 GLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDIN 221
Query: 112 ECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
EC+ C A C N G+F+C+C GY+
Sbjct: 222 ECTMDSHTCSHHANCFNTQGSFKCKCKQGYK 252
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/107 (33%), Positives = 43/107 (40%), Gaps = 13/107 (12%)
Query: 755 PGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 814
PG+C G C R + VC E + C G C C GY
Sbjct: 38 PGVCHYGTKLACCYGWRRNSKGVCEATCEPGCKFGECV-------GPNKCRCFPGYT--- 87
Query: 815 DGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
G C +DV+EC CQ C NT GSY+C C G+ DA CV
Sbjct: 88 -GKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDATCV 133
Score = 43.2 bits (97), Expect = 0.004
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 16/92 (17%)
Query: 747 DVDECAAIPGLCAPGR--------FRCVCGPGYRP---AGEV-CADVDECAVRPPPCDQ- 793
D+DECA+ +C R + C C G+ +G C D++EC + C
Sbjct: 174 DIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHH 233
Query: 794 -LCHNTDGSYDCLCRTGYELDEDGANCRDVDE 824
C NT GS+ C C+ GY+ +G C + E
Sbjct: 234 ANCFNTQGSFKCKCKQGYK--GNGLRCSAIPE 263
>AY358333-1|AAQ88699.1| 338|Homo sapiens EGFL6 protein.
Length = 338
Score = 131 bits (316), Expect = 1e-29
Identities = 75/196 (38%), Positives = 93/196 (47%), Gaps = 17/196 (8%)
Query: 437 CVGGRCVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGNGTCSNTRGGYECQC 495
C G CV G +C C GY G +C D +EC + PR C + C NT G Y+C C
Sbjct: 69 CKFGECV---GPNKCRCFPGYT----GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFC 120
Query: 496 SPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPY-GYAVAADGVHCRDIDEC 554
G PD TCV+ CA +C + C +T +C CP G +A +G C DIDEC
Sbjct: 121 LSGHMLMPDATCVNSRTCA--MINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDEC 178
Query: 555 VQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-C 611
+CP+ C N GSY CKC G+ C DINEC CS C
Sbjct: 179 ASGKVICPYNRRCVNTFGSYYCKCHIGFELQYI--SGRYDCIDINECTMDSHTCSHHANC 236
Query: 612 INTDGSFLCDCDAGFE 627
NT GSF C C G++
Sbjct: 237 FNTQGSFKCKCKQGYK 252
Score = 130 bits (314), Expect = 2e-29
Identities = 87/244 (35%), Positives = 122/244 (50%), Gaps = 29/244 (11%)
Query: 79 KPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCP 138
+PG CH G + C +G+ N+ +C E P C+ +CV G +CRC
Sbjct: 37 QPGVCH---YGTKLACCYGWRR-NSKGVCEATCE-----PGCK-FGECV---GPNKCRCF 83
Query: 139 PGYRLTPSLDECEDVDECGDQ-RICDHGDCRNTIGSYRCECKPGYTLRENV-CRDVDECS 196
PGY +DV+ECG + R C H C NT GSY+C C G+ L + C + C+
Sbjct: 84 PGYTGKTC---SQDVNECGMKPRPCQHR-CVNTHGSYKCFCLSGHMLMPDATCVNSRTCA 139
Query: 197 RPRPVCRNGTCENLPGAYLCHC-DDGFKAGPNN-DCVDVNECREGGMVCR-NGRCRNTVG 253
C+ +CE+ C C G + PN DC+D++EC G ++C N RC NT G
Sbjct: 140 MIN--CQY-SCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFG 196
Query: 254 SFRCECAPGYTLT-ADGR-NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
S+ C+C G+ L GR +C D++EC H C N C NT G ++C C G+K
Sbjct: 197 SYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHAN--CFNTQGSFKCKCKQGYKGN 254
Query: 312 GRRC 315
G RC
Sbjct: 255 GLRC 258
Score = 130 bits (313), Expect = 3e-29
Identities = 73/204 (35%), Positives = 106/204 (51%), Gaps = 21/204 (10%)
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNT 445
E C G +G C P+ C G +QD++EC ++P C RCVNT
Sbjct: 62 EATCEPGCKFGE----CVGPNKCR----CFPGYTGKTCSQDVNECGMKPRPCQH-RCVNT 112
Query: 446 DGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQC-SPGFTQGPD 504
GS++C C G++L PD +CV++ CA+ I +C +T G +C C S G P+
Sbjct: 113 HGSYKCFCLSGHMLMPDA-TCVNSRTCAM---INCQYSCEDTEEGPQCLCPSSGLRLAPN 168
Query: 505 -QTCVDVDECAEGRASCTF--RCHNTAGSFRCTCPYGYAV--AADGVHCRDIDECVQEPR 559
+ C+D+DECA G+ C + RC NT GS+ C C G+ + + C DI+EC +
Sbjct: 169 GRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSH 228
Query: 560 VCPH--ACENVVGSYICKCPEGYR 581
C H C N GS+ CKC +GY+
Sbjct: 229 TCSHHANCFNTQGSFKCKCKQGYK 252
Score = 109 bits (263), Expect = 3e-23
Identities = 75/220 (34%), Positives = 105/220 (47%), Gaps = 23/220 (10%)
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECS 196
C G+R S CE E G C G+C +G +C C PGYT + +DV+EC
Sbjct: 49 CCYGWRRN-SKGVCEATCEPG----CKFGEC---VGPNKCRCFPGYT-GKTCSQDVNECG 99
Query: 197 -RPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSF 255
+PRP C++ C N G+Y C C G P+ CV+ C M+ C +T
Sbjct: 100 MKPRP-CQH-RCVNTHGSYKCFCLSGHMLMPDATCVNSRTC---AMINCQYSCEDTEEGP 154
Query: 256 RCEC-APGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--- 311
+C C + G L +GR+C D+DEC C N C NT G Y C C G++L
Sbjct: 155 QCLCPSSGLRLAPNGRDCLDIDECASGKVICPY--NRRCVNTFGSYYCKCHIGFELQYIS 212
Query: 312 GRR-CVDRDECKELPYVCAG-GECRNFNGGYVCECPAGWR 349
GR C+D +EC + C+ C N G + C+C G++
Sbjct: 213 GRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYK 252
Score = 86.6 bits (205), Expect = 3e-16
Identities = 57/163 (34%), Positives = 76/163 (46%), Gaps = 16/163 (9%)
Query: 479 CGNGTCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRASCTFRCHNTAGSFRCTCPY 537
C G C G +C+C PG+T +TC DV+EC C RC NT GS++C C
Sbjct: 69 CKFGECV---GPNKCRCFPGYT---GKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLS 122
Query: 538 GYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDIN 597
G+ + D C + C C ++CE+ C CP R AP + C DI+
Sbjct: 123 GHMLMPDAT-CVNSRTCAMIN--CQYSCEDTEEGPQCLCPSSGLRL-APNGRD--CLDID 176
Query: 598 ECEEQEDLCS-GGVCINTDGSFLCDCDAGFEPS--EDGTDCID 637
EC + +C C+NT GS+ C C GFE DCID
Sbjct: 177 ECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCID 219
Score = 84.6 bits (200), Expect = 1e-15
Identities = 43/104 (41%), Positives = 58/104 (55%), Gaps = 9/104 (8%)
Query: 764 RCVC-GPGYR--PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGA- 817
+C+C G R P G C D+DECA C ++ C NT GSY C C G+EL
Sbjct: 155 QCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGR 214
Query: 818 -NCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDAC 858
+C D++EC D+HTC C NT+GS++C C+ GY+ G C
Sbjct: 215 YDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRC 258
Score = 81.4 bits (192), Expect = 1e-14
Identities = 47/141 (33%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Query: 82 TCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
+C DT G QC C G C D+DEC+ G+ C +CVN G++ C+C G
Sbjct: 146 SCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIG 205
Query: 141 YRL--TPSLDECEDVDECG-DQRICD-HGDCRNTIGSYRCECKPGYTLRENVCRDVDECS 196
+ L +C D++EC D C H +C NT GS++C+CK GY C + E S
Sbjct: 206 FELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENS 265
Query: 197 RPRPVCRNGTCENLPGAYLCH 217
+ GT ++ L H
Sbjct: 266 VKEVLRAPGTIKDRIKKLLAH 286
Score = 71.3 bits (167), Expect = 1e-11
Identities = 38/93 (40%), Positives = 49/93 (52%), Gaps = 7/93 (7%)
Query: 756 GLCAPGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 814
G C G +C C PGY G+ C+ DV+EC ++P PC C NT GSY C C +G+ L
Sbjct: 72 GECV-GPNKCRCFPGY--TGKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMP 128
Query: 815 DGANCRDVDECERDTHTCQQICSNTEGSYECSC 847
D A C + C CQ C +TE +C C
Sbjct: 129 D-ATCVNSRTCA--MINCQYSCEDTEEGPQCLC 158
Score = 52.0 bits (119), Expect = 9e-06
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 55 GEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTS--HLCRDVD 111
G + P + IDEC +C C +T + C C G+E S + C D++
Sbjct: 162 GLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDIN 221
Query: 112 ECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
EC+ C A C N G+F+C+C GY+
Sbjct: 222 ECTMDSHTCSHHANCFNTQGSFKCKCKQGYK 252
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/107 (33%), Positives = 43/107 (40%), Gaps = 13/107 (12%)
Query: 755 PGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 814
PG+C G C R + VC E + C G C C GY
Sbjct: 38 PGVCHYGTKLACCYGWRRNSKGVCEATCEPGCKFGECV-------GPNKCRCFPGYT--- 87
Query: 815 DGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
G C +DV+EC CQ C NT GSY+C C G+ DA CV
Sbjct: 88 -GKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDATCV 133
Score = 43.2 bits (97), Expect = 0.004
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 16/92 (17%)
Query: 747 DVDECAAIPGLCAPGR--------FRCVCGPGYRP---AGEV-CADVDECAVRPPPCDQ- 793
D+DECA+ +C R + C C G+ +G C D++EC + C
Sbjct: 174 DIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHH 233
Query: 794 -LCHNTDGSYDCLCRTGYELDEDGANCRDVDE 824
C NT GS+ C C+ GY+ +G C + E
Sbjct: 234 ANCFNTQGSFKCKCKQGYK--GNGLRCSAIPE 263
>AK092062-1|BAC03798.1| 880|Homo sapiens protein ( Homo sapiens
cDNA FLJ34743 fis, clone MESAN2009019, moderately
similar to CEGP1 protein. ).
Length = 880
Score = 131 bits (316), Expect = 1e-29
Identities = 80/233 (34%), Positives = 109/233 (46%), Gaps = 25/233 (10%)
Query: 423 LTQDLDECRVRPDVCVGG---RCVNTDGSFRCECPDGYVLAPDGLSCVDAD--ECALDPR 477
LT++ +C++ + GG C +T+ RC C +VL DG +C+ E + +
Sbjct: 61 LTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIGERRLEQHIPTQ 120
Query: 478 ICGNGTCSNTRGGYE-----------CQCSPGFTQGPDQ-TCVDVDECAEGRASCTFRCH 525
N TC+ GG + C C GF PD+ TC D+DEC C C
Sbjct: 121 AVSNETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICR 180
Query: 526 NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSA 585
NT GSF C+C GY + + +C+DIDEC + R C H C N GS+ C C GY
Sbjct: 181 NTVGSFECSCKKGYKLLINERNCQDIDECSFD-RTCDHICVNTPGSFQCLCHRGYLLYGI 239
Query: 586 PQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSE-DGTDCID 637
C D++EC C G CINT GS+ C C AG +G DC +
Sbjct: 240 TH-----CGDVDECSINRGGCRFG-CINTPGSYQCTCPAGQGRLHWNGKDCTE 286
Score = 123 bits (297), Expect = 2e-27
Identities = 97/318 (30%), Positives = 130/318 (40%), Gaps = 36/318 (11%)
Query: 252 VGSFRCECAPGYTLTADGRNCRDVDE----CDELPHPCGRDGNPSCTNT-NGGYECSCGA 306
+GS+ C C G+ L+ + C E C H C C T GG C C
Sbjct: 2 MGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAH----ICRETPKGGIACECRP 57
Query: 307 GWKLVGRRCVDRDECKELPYVCAGG---ECRNFNGGYVCECPAGWRFDKTAAVCVDERKE 363
G++L + RD CK GG C + G C C + C+ ER
Sbjct: 58 GFELTKNQ---RD-CKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIGER-- 111
Query: 364 LCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPN- 422
R + P Q E C G +C + G M +P+
Sbjct: 112 ---------RLEQHIPTQAVSNETCAVNN---GGCDSKCHDAATGVHCTCPVGFMLQPDR 159
Query: 423 -LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGN 481
+D+DECR+ C C NT GSF C C GY L + +C D DEC+ D R C +
Sbjct: 160 KTCKDIDECRLNNGGC-DHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFD-RTCDH 217
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA- 540
C NT G ++C C G+ C DVDEC+ R C F C NT GS++CTCP G
Sbjct: 218 -ICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGR 276
Query: 541 VAADGVHCRDIDECVQEP 558
+ +G C + +C P
Sbjct: 277 LHWNGKDCTEPLKCQGSP 294
Score = 122 bits (295), Expect = 4e-27
Identities = 91/279 (32%), Positives = 120/279 (43%), Gaps = 31/279 (11%)
Query: 90 FQCGCDHGYEHDNTSHLCRDVDECSWG-RPPCRGMAQ-CVNLP-GAFECRCPPGYRLTPS 146
++C C G+ + H C E G A C P G C C PG+ LT +
Sbjct: 5 YECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKN 64
Query: 147 LDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VC---RDVDE------C 195
+C+ G+ C H C +T RC C + L + C R +++
Sbjct: 65 QRDCKLTCNYGNGG-CQH-TCDDTEQGPRCGCHIKFVLHTDGKTCIGERRLEQHIPTQAV 122
Query: 196 SRPRPVCRNGTCEN-----LPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRNGRCR 249
S NG C++ G + C C GF P+ C D++ECR C + CR
Sbjct: 123 SNETCAVNNGGCDSKCHDAATGVH-CTCPVGFMLQPDRKTCKDIDECRLNNGGCDH-ICR 180
Query: 250 NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWK 309
NTVGSF C C GY L + RNC+D+DEC R + C NT G ++C C G+
Sbjct: 181 NTVGSFECSCKKGYKLLINERNCQDIDECS-----FDRTCDHICVNTPGSFQCLCHRGYL 235
Query: 310 LVG-RRCVDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
L G C D DEC C G C N G Y C CPAG
Sbjct: 236 LYGITHCGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 273
Score = 110 bits (264), Expect = 2e-23
Identities = 65/195 (33%), Positives = 85/195 (43%), Gaps = 24/195 (12%)
Query: 447 GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPD-Q 505
G CEC G+ L + C C C + TC +T G C C F D +
Sbjct: 49 GGIACECRPGFELTKNQRDCKLT--CNYGNGGCQH-TCDDTEQGPRCGCHIKFVLHTDGK 105
Query: 506 TC--------------VDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDI 551
TC V + CA C +CH+ A CTCP G+ + D C+DI
Sbjct: 106 TCIGERRLEQHIPTQAVSNETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDI 165
Query: 552 DECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVC 611
DEC C H C N VGS+ C C +GY+ +E C+DI+EC D +C
Sbjct: 166 DECRLNNGGCDHICRNTVGSFECSCKKGYKLLI----NERNCQDIDEC--SFDRTCDHIC 219
Query: 612 INTDGSFLCDCDAGF 626
+NT GSF C C G+
Sbjct: 220 VNTPGSFQCLCHRGY 234
Score = 98.7 bits (235), Expect = 8e-20
Identities = 40/89 (44%), Positives = 55/89 (61%), Gaps = 3/89 (3%)
Query: 765 CVCGPGY--RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDV 822
C C G+ +P + C D+DEC + CD +C NT GS++C C+ GY+L + NC+D+
Sbjct: 147 CTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDI 206
Query: 823 DECERDTHTCQQICSNTEGSYECSCEDGY 851
DEC D TC IC NT GS++C C GY
Sbjct: 207 DECSFD-RTCDHICVNTPGSFQCLCHRGY 234
Score = 86.2 bits (204), Expect = 4e-16
Identities = 46/112 (41%), Positives = 57/112 (50%), Gaps = 10/112 (8%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNT 798
D+DEC G C G F C C GY+ C D+DEC+ CD +C NT
Sbjct: 164 DIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSF-DRTCDHICVNT 222
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
GS+ CLC GY L +C DVDEC + C+ C NT GSY+C+C G
Sbjct: 223 PGSFQCLCHRGYLL-YGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAG 273
Score = 85.0 bits (201), Expect = 1e-15
Identities = 93/349 (26%), Positives = 132/349 (37%), Gaps = 60/349 (17%)
Query: 171 IGSYRCECKPGYTLREN--VCRDVDE----CSRPRPVCRNGTCENLPGAYLCHCDDGFKA 224
+GSY C C+ G+ L +N C E C C + E G C C GF+
Sbjct: 2 MGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFEL 61
Query: 225 GPN-NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPH 283
N DC C G C++ C +T RC C + L DG+ C ++
Sbjct: 62 TKNQRDC--KLTCNYGNGGCQH-TCDDTEQGPRCGCHIKFVLHTDGKTCIGERRLEQ-HI 117
Query: 284 PCGRDGNPSCTNTNGGYE-----------CSCGAGWKLVGRR--CVDRDECKELPYVCAG 330
P N +C NGG + C+C G+ L R C D DEC+ C
Sbjct: 118 PTQAVSNETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGC-D 176
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCS 390
CRN G + C C G++ + ++ER C D EC
Sbjct: 177 HICRNTVGSFECSCKKGYK------LLINERN--CQD----------------IDEC--- 209
Query: 391 EGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQ--DLDECRVRPDVCVGGRCVNTDGS 448
++ R C+ F +C G +T D+DEC + C G C+NT GS
Sbjct: 210 ---SFDRTCDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFG-CINTPGS 265
Query: 449 FRCECPDGY-VLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCS 496
++C CP G L +G C + +C P S R G + C+
Sbjct: 266 YQCTCPAGQGRLHWNGKDCTEPLKCQGSPG-ASKAMLSCNRSGKKDTCA 313
Score = 78.2 bits (184), Expect = 1e-13
Identities = 30/71 (42%), Positives = 39/71 (54%)
Query: 782 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEG 841
+ CAV CD CH+ C C G+ L D C+D+DEC + C IC NT G
Sbjct: 125 ETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVG 184
Query: 842 SYECSCEDGYE 852
S+ECSC+ GY+
Sbjct: 185 SFECSCKKGYK 195
Score = 44.0 bits (99), Expect = 0.002
Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 5/58 (8%)
Query: 800 GSYDCLCRTGYELDEDGANCRDVDE----CERDTHTCQQICSNT-EGSYECSCEDGYE 852
GSY+C CR G+ L ++ C E C H C IC T +G C C G+E
Sbjct: 3 GSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFE 60
Score = 42.3 bits (95), Expect = 0.007
Identities = 31/117 (26%), Positives = 45/117 (38%), Gaps = 14/117 (11%)
Query: 529 GSFRCTCPYGYAVAADGVHCRDIDE----CVQEPRVCPHAC-ENVVGSYICKCPEGYRRT 583
GS+ C C G+ ++ + C E C+ + C H C E G C+C G+ T
Sbjct: 3 GSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELT 62
Query: 584 SAPQDSENACEDINE-CEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRR 639
+D + C N C+ C +T+ C C F DG CI R
Sbjct: 63 KNQRDCKLTCNYGNGGCQH--------TCDDTEQGPRCGCHIKFVLHTDGKTCIGER 111
Score = 37.5 bits (83), Expect = 0.20
Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 2/69 (2%)
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTD-GSFLCDCDAGF 626
++GSY C C EG+ + E+ C + C+ +C T G C+C GF
Sbjct: 1 MMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAH-ICRETPKGGIACECRPGF 59
Query: 627 EPSEDGTDC 635
E +++ DC
Sbjct: 60 ELTKNQRDC 68
Score = 33.9 bits (74), Expect = 2.5
Identities = 24/102 (23%), Positives = 32/102 (31%), Gaps = 3/102 (2%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
CA I G C C PG+ C C C +T+ C C +
Sbjct: 39 CAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKF 98
Query: 811 ELDEDGANCRDVDECERDTHT---CQQICSNTEGSYECSCED 849
L DG C E+ T + C+ G + C D
Sbjct: 99 VLHTDGKTCIGERRLEQHIPTQAVSNETCAVNNGGCDSKCHD 140
>AK075214-1|BAC11477.1| 553|Homo sapiens protein ( Homo sapiens
cDNA FLJ90733 fis, clone PLACE1010251, highly similar to
Epidermal growth factor-like protein 6 precursor. ).
Length = 553
Score = 131 bits (316), Expect = 1e-29
Identities = 75/196 (38%), Positives = 93/196 (47%), Gaps = 17/196 (8%)
Query: 437 CVGGRCVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGNGTCSNTRGGYECQC 495
C G CV G +C C GY G +C D +EC + PR C + C NT G Y+C C
Sbjct: 69 CKFGECV---GPNKCRCFPGYT----GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFC 120
Query: 496 SPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPY-GYAVAADGVHCRDIDEC 554
G PD TCV+ CA +C + C +T +C CP G +A +G C DIDEC
Sbjct: 121 LSGHMLMPDATCVNSRTCA--MINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDEC 178
Query: 555 VQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-C 611
+CP+ C N GSY CKC G+ C DINEC CS C
Sbjct: 179 ASGKVICPYNRRCVNTFGSYYCKCHIGFELQYI--SGRYDCIDINECTMDSHTCSHHANC 236
Query: 612 INTDGSFLCDCDAGFE 627
NT GSF C C G++
Sbjct: 237 FNTQGSFKCKCKQGYK 252
Score = 130 bits (314), Expect = 2e-29
Identities = 87/244 (35%), Positives = 122/244 (50%), Gaps = 29/244 (11%)
Query: 79 KPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCP 138
+PG CH G + C +G+ N+ +C E P C+ +CV G +CRC
Sbjct: 37 QPGVCH---YGTKLACCYGWRR-NSKGVCEATCE-----PGCK-FGECV---GPNKCRCF 83
Query: 139 PGYRLTPSLDECEDVDECGDQ-RICDHGDCRNTIGSYRCECKPGYTLRENV-CRDVDECS 196
PGY +DV+ECG + R C H C NT GSY+C C G+ L + C + C+
Sbjct: 84 PGYTGKTC---SQDVNECGMKPRPCQHR-CVNTHGSYKCFCLSGHMLMPDATCVNSRTCA 139
Query: 197 RPRPVCRNGTCENLPGAYLCHC-DDGFKAGPNN-DCVDVNECREGGMVCR-NGRCRNTVG 253
C+ +CE+ C C G + PN DC+D++EC G ++C N RC NT G
Sbjct: 140 MIN--CQY-SCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFG 196
Query: 254 SFRCECAPGYTLT-ADGR-NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
S+ C+C G+ L GR +C D++EC H C N C NT G ++C C G+K
Sbjct: 197 SYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHAN--CFNTQGSFKCKCKQGYKGN 254
Query: 312 GRRC 315
G RC
Sbjct: 255 GLRC 258
Score = 130 bits (313), Expect = 3e-29
Identities = 73/204 (35%), Positives = 106/204 (51%), Gaps = 21/204 (10%)
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNT 445
E C G +G C P+ C G +QD++EC ++P C RCVNT
Sbjct: 62 EATCEPGCKFGE----CVGPNKCR----CFPGYTGKTCSQDVNECGMKPRPCQH-RCVNT 112
Query: 446 DGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQC-SPGFTQGPD 504
GS++C C G++L PD +CV++ CA+ I +C +T G +C C S G P+
Sbjct: 113 HGSYKCFCLSGHMLMPDA-TCVNSRTCAM---INCQYSCEDTEEGPQCLCPSSGLRLAPN 168
Query: 505 -QTCVDVDECAEGRASCTF--RCHNTAGSFRCTCPYGYAV--AADGVHCRDIDECVQEPR 559
+ C+D+DECA G+ C + RC NT GS+ C C G+ + + C DI+EC +
Sbjct: 169 GRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSH 228
Query: 560 VCPH--ACENVVGSYICKCPEGYR 581
C H C N GS+ CKC +GY+
Sbjct: 229 TCSHHANCFNTQGSFKCKCKQGYK 252
Score = 109 bits (263), Expect = 3e-23
Identities = 75/220 (34%), Positives = 105/220 (47%), Gaps = 23/220 (10%)
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECS 196
C G+R S CE E G C G+C +G +C C PGYT + +DV+EC
Sbjct: 49 CCYGWRRN-SKGVCEATCEPG----CKFGEC---VGPNKCRCFPGYT-GKTCSQDVNECG 99
Query: 197 -RPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSF 255
+PRP C++ C N G+Y C C G P+ CV+ C M+ C +T
Sbjct: 100 MKPRP-CQH-RCVNTHGSYKCFCLSGHMLMPDATCVNSRTC---AMINCQYSCEDTEEGP 154
Query: 256 RCEC-APGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--- 311
+C C + G L +GR+C D+DEC C N C NT G Y C C G++L
Sbjct: 155 QCLCPSSGLRLAPNGRDCLDIDECASGKVICPY--NRRCVNTFGSYYCKCHIGFELQYIS 212
Query: 312 GRR-CVDRDECKELPYVCAG-GECRNFNGGYVCECPAGWR 349
GR C+D +EC + C+ C N G + C+C G++
Sbjct: 213 GRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYK 252
Score = 86.6 bits (205), Expect = 3e-16
Identities = 57/163 (34%), Positives = 76/163 (46%), Gaps = 16/163 (9%)
Query: 479 CGNGTCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRASCTFRCHNTAGSFRCTCPY 537
C G C G +C+C PG+T +TC DV+EC C RC NT GS++C C
Sbjct: 69 CKFGECV---GPNKCRCFPGYT---GKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLS 122
Query: 538 GYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDIN 597
G+ + D C + C C ++CE+ C CP R AP + C DI+
Sbjct: 123 GHMLMPDAT-CVNSRTCAMIN--CQYSCEDTEEGPQCLCPSSGLRL-APNGRD--CLDID 176
Query: 598 ECEEQEDLCS-GGVCINTDGSFLCDCDAGFEPS--EDGTDCID 637
EC + +C C+NT GS+ C C GFE DCID
Sbjct: 177 ECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCID 219
Score = 84.6 bits (200), Expect = 1e-15
Identities = 43/104 (41%), Positives = 58/104 (55%), Gaps = 9/104 (8%)
Query: 764 RCVC-GPGYR--PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGA- 817
+C+C G R P G C D+DECA C ++ C NT GSY C C G+EL
Sbjct: 155 QCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGR 214
Query: 818 -NCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDAC 858
+C D++EC D+HTC C NT+GS++C C+ GY+ G C
Sbjct: 215 YDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRC 258
Score = 81.4 bits (192), Expect = 1e-14
Identities = 47/141 (33%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Query: 82 TCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
+C DT G QC C G C D+DEC+ G+ C +CVN G++ C+C G
Sbjct: 146 SCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIG 205
Query: 141 YRL--TPSLDECEDVDECG-DQRICD-HGDCRNTIGSYRCECKPGYTLRENVCRDVDECS 196
+ L +C D++EC D C H +C NT GS++C+CK GY C + E S
Sbjct: 206 FELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENS 265
Query: 197 RPRPVCRNGTCENLPGAYLCH 217
+ GT ++ L H
Sbjct: 266 VKEVLRAPGTIKDRIKKLLAH 286
Score = 71.3 bits (167), Expect = 1e-11
Identities = 38/93 (40%), Positives = 49/93 (52%), Gaps = 7/93 (7%)
Query: 756 GLCAPGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 814
G C G +C C PGY G+ C+ DV+EC ++P PC C NT GSY C C +G+ L
Sbjct: 72 GECV-GPNKCRCFPGY--TGKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMP 128
Query: 815 DGANCRDVDECERDTHTCQQICSNTEGSYECSC 847
D A C + C CQ C +TE +C C
Sbjct: 129 D-ATCVNSRTCA--MINCQYSCEDTEEGPQCLC 158
Score = 52.0 bits (119), Expect = 9e-06
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 55 GEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTS--HLCRDVD 111
G + P + IDEC +C C +T + C C G+E S + C D++
Sbjct: 162 GLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDIN 221
Query: 112 ECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
EC+ C A C N G+F+C+C GY+
Sbjct: 222 ECTMDSHTCSHHANCFNTQGSFKCKCKQGYK 252
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/107 (33%), Positives = 43/107 (40%), Gaps = 13/107 (12%)
Query: 755 PGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 814
PG+C G C R + VC E + C G C C GY
Sbjct: 38 PGVCHYGTKLACCYGWRRNSKGVCEATCEPGCKFGECV-------GPNKCRCFPGYT--- 87
Query: 815 DGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
G C +DV+EC CQ C NT GSY+C C G+ DA CV
Sbjct: 88 -GKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDATCV 133
Score = 43.2 bits (97), Expect = 0.004
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 16/92 (17%)
Query: 747 DVDECAAIPGLCAPGR--------FRCVCGPGYRP---AGEV-CADVDECAVRPPPCDQ- 793
D+DECA+ +C R + C C G+ +G C D++EC + C
Sbjct: 174 DIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHH 233
Query: 794 -LCHNTDGSYDCLCRTGYELDEDGANCRDVDE 824
C NT GS+ C C+ GY+ +G C + E
Sbjct: 234 ANCFNTQGSFKCKCKQGYK--GNGLRCSAIPE 263
>AJ245671-1|CAB92132.1| 554|Homo sapiens hypothetical protein
protein.
Length = 554
Score = 131 bits (316), Expect = 1e-29
Identities = 75/196 (38%), Positives = 93/196 (47%), Gaps = 17/196 (8%)
Query: 437 CVGGRCVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGNGTCSNTRGGYECQC 495
C G CV G +C C GY G +C D +EC + PR C + C NT G Y+C C
Sbjct: 69 CKFGECV---GPNKCRCFPGYT----GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFC 120
Query: 496 SPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPY-GYAVAADGVHCRDIDEC 554
G PD TCV+ CA +C + C +T +C CP G +A +G C DIDEC
Sbjct: 121 LSGHMLMPDATCVNSRTCA--MINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDEC 178
Query: 555 VQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-C 611
+CP+ C N GSY CKC G+ C DINEC CS C
Sbjct: 179 ASGKVICPYNRRCVNTFGSYYCKCHIGFELQYI--SGRYDCIDINECTMDSHTCSHHANC 236
Query: 612 INTDGSFLCDCDAGFE 627
NT GSF C C G++
Sbjct: 237 FNTQGSFKCKCKQGYK 252
Score = 130 bits (314), Expect = 2e-29
Identities = 87/244 (35%), Positives = 122/244 (50%), Gaps = 29/244 (11%)
Query: 79 KPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCP 138
+PG CH G + C +G+ N+ +C E P C+ +CV G +CRC
Sbjct: 37 QPGVCH---YGTKLACCYGWRR-NSKGVCEATCE-----PGCK-FGECV---GPNKCRCF 83
Query: 139 PGYRLTPSLDECEDVDECGDQ-RICDHGDCRNTIGSYRCECKPGYTLRENV-CRDVDECS 196
PGY +DV+ECG + R C H C NT GSY+C C G+ L + C + C+
Sbjct: 84 PGYTGKTC---SQDVNECGMKPRPCQHR-CVNTHGSYKCFCLSGHMLMPDATCVNSRTCA 139
Query: 197 RPRPVCRNGTCENLPGAYLCHC-DDGFKAGPNN-DCVDVNECREGGMVCR-NGRCRNTVG 253
C+ +CE+ C C G + PN DC+D++EC G ++C N RC NT G
Sbjct: 140 MIN--CQY-SCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFG 196
Query: 254 SFRCECAPGYTLT-ADGR-NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
S+ C+C G+ L GR +C D++EC H C N C NT G ++C C G+K
Sbjct: 197 SYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHAN--CFNTQGSFKCKCKQGYKGN 254
Query: 312 GRRC 315
G RC
Sbjct: 255 GLRC 258
Score = 130 bits (313), Expect = 3e-29
Identities = 73/204 (35%), Positives = 106/204 (51%), Gaps = 21/204 (10%)
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNT 445
E C G +G C P+ C G +QD++EC ++P C RCVNT
Sbjct: 62 EATCEPGCKFGE----CVGPNKCR----CFPGYTGKTCSQDVNECGMKPRPCQH-RCVNT 112
Query: 446 DGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQC-SPGFTQGPD 504
GS++C C G++L PD +CV++ CA+ I +C +T G +C C S G P+
Sbjct: 113 HGSYKCFCLSGHMLMPDA-TCVNSRTCAM---INCQYSCEDTEEGPQCLCPSSGLRLAPN 168
Query: 505 -QTCVDVDECAEGRASCTF--RCHNTAGSFRCTCPYGYAV--AADGVHCRDIDECVQEPR 559
+ C+D+DECA G+ C + RC NT GS+ C C G+ + + C DI+EC +
Sbjct: 169 GRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSH 228
Query: 560 VCPH--ACENVVGSYICKCPEGYR 581
C H C N GS+ CKC +GY+
Sbjct: 229 TCSHHANCFNTQGSFKCKCKQGYK 252
Score = 109 bits (263), Expect = 3e-23
Identities = 75/220 (34%), Positives = 105/220 (47%), Gaps = 23/220 (10%)
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECS 196
C G+R S CE E G C G+C +G +C C PGYT + +DV+EC
Sbjct: 49 CCYGWRRN-SKGVCEATCEPG----CKFGEC---VGPNKCRCFPGYT-GKTCSQDVNECG 99
Query: 197 -RPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSF 255
+PRP C++ C N G+Y C C G P+ CV+ C M+ C +T
Sbjct: 100 MKPRP-CQH-RCVNTHGSYKCFCLSGHMLMPDATCVNSRTC---AMINCQYSCEDTEEGP 154
Query: 256 RCEC-APGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--- 311
+C C + G L +GR+C D+DEC C N C NT G Y C C G++L
Sbjct: 155 QCLCPSSGLRLAPNGRDCLDIDECASGKVICPY--NRRCVNTFGSYYCKCHIGFELQYIS 212
Query: 312 GRR-CVDRDECKELPYVCAG-GECRNFNGGYVCECPAGWR 349
GR C+D +EC + C+ C N G + C+C G++
Sbjct: 213 GRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYK 252
Score = 86.6 bits (205), Expect = 3e-16
Identities = 57/163 (34%), Positives = 76/163 (46%), Gaps = 16/163 (9%)
Query: 479 CGNGTCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRASCTFRCHNTAGSFRCTCPY 537
C G C G +C+C PG+T +TC DV+EC C RC NT GS++C C
Sbjct: 69 CKFGECV---GPNKCRCFPGYT---GKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLS 122
Query: 538 GYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDIN 597
G+ + D C + C C ++CE+ C CP R AP + C DI+
Sbjct: 123 GHMLMPDAT-CVNSRTCAMIN--CQYSCEDTEEGPQCLCPSSGLRL-APNGRD--CLDID 176
Query: 598 ECEEQEDLCS-GGVCINTDGSFLCDCDAGFEPS--EDGTDCID 637
EC + +C C+NT GS+ C C GFE DCID
Sbjct: 177 ECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCID 219
Score = 84.6 bits (200), Expect = 1e-15
Identities = 43/104 (41%), Positives = 58/104 (55%), Gaps = 9/104 (8%)
Query: 764 RCVC-GPGYR--PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGA- 817
+C+C G R P G C D+DECA C ++ C NT GSY C C G+EL
Sbjct: 155 QCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGR 214
Query: 818 -NCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDAC 858
+C D++EC D+HTC C NT+GS++C C+ GY+ G C
Sbjct: 215 YDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRC 258
Score = 81.4 bits (192), Expect = 1e-14
Identities = 47/141 (33%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Query: 82 TCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
+C DT G QC C G C D+DEC+ G+ C +CVN G++ C+C G
Sbjct: 146 SCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIG 205
Query: 141 YRL--TPSLDECEDVDECG-DQRICD-HGDCRNTIGSYRCECKPGYTLRENVCRDVDECS 196
+ L +C D++EC D C H +C NT GS++C+CK GY C + E S
Sbjct: 206 FELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENS 265
Query: 197 RPRPVCRNGTCENLPGAYLCH 217
+ GT ++ L H
Sbjct: 266 VKEVLRAPGTIKDRIKKLLAH 286
Score = 71.3 bits (167), Expect = 1e-11
Identities = 38/93 (40%), Positives = 49/93 (52%), Gaps = 7/93 (7%)
Query: 756 GLCAPGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 814
G C G +C C PGY G+ C+ DV+EC ++P PC C NT GSY C C +G+ L
Sbjct: 72 GECV-GPNKCRCFPGY--TGKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMP 128
Query: 815 DGANCRDVDECERDTHTCQQICSNTEGSYECSC 847
D A C + C CQ C +TE +C C
Sbjct: 129 D-ATCVNSRTCA--MINCQYSCEDTEEGPQCLC 158
Score = 52.0 bits (119), Expect = 9e-06
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 55 GEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTS--HLCRDVD 111
G + P + IDEC +C C +T + C C G+E S + C D++
Sbjct: 162 GLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDIN 221
Query: 112 ECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
EC+ C A C N G+F+C+C GY+
Sbjct: 222 ECTMDSHTCSHHANCFNTQGSFKCKCKQGYK 252
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/107 (33%), Positives = 43/107 (40%), Gaps = 13/107 (12%)
Query: 755 PGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 814
PG+C G C R + VC E + C G C C GY
Sbjct: 38 PGVCHYGTKLACCYGWRRNSKGVCEATCEPGCKFGECV-------GPNKCRCFPGYT--- 87
Query: 815 DGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
G C +DV+EC CQ C NT GSY+C C G+ DA CV
Sbjct: 88 -GKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDATCV 133
Score = 43.2 bits (97), Expect = 0.004
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 16/92 (17%)
Query: 747 DVDECAAIPGLCAPGR--------FRCVCGPGYRP---AGEV-CADVDECAVRPPPCDQ- 793
D+DECA+ +C R + C C G+ +G C D++EC + C
Sbjct: 174 DIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHH 233
Query: 794 -LCHNTDGSYDCLCRTGYELDEDGANCRDVDE 824
C NT GS+ C C+ GY+ +G C + E
Sbjct: 234 ANCFNTQGSFKCKCKQGYK--GNGLRCSAIPE 263
>AF186084-1|AAF27812.1| 553|Homo sapiens epidermal growth factor
repeat containing protein protein.
Length = 553
Score = 131 bits (316), Expect = 1e-29
Identities = 75/196 (38%), Positives = 93/196 (47%), Gaps = 17/196 (8%)
Query: 437 CVGGRCVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGNGTCSNTRGGYECQC 495
C G CV G +C C GY G +C D +EC + PR C + C NT G Y+C C
Sbjct: 69 CKFGECV---GPNKCRCFPGYT----GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFC 120
Query: 496 SPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPY-GYAVAADGVHCRDIDEC 554
G PD TCV+ CA +C + C +T +C CP G +A +G C DIDEC
Sbjct: 121 LSGHMLMPDATCVNSRTCA--MINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDEC 178
Query: 555 VQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGV-C 611
+CP+ C N GSY CKC G+ C DINEC CS C
Sbjct: 179 ASGKVICPYNRRCVNTFGSYYCKCHIGFELQYI--SGRYDCIDINECTMDSHTCSHHANC 236
Query: 612 INTDGSFLCDCDAGFE 627
NT GSF C C G++
Sbjct: 237 FNTQGSFKCKCKQGYK 252
Score = 130 bits (314), Expect = 2e-29
Identities = 87/244 (35%), Positives = 122/244 (50%), Gaps = 29/244 (11%)
Query: 79 KPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCP 138
+PG CH G + C +G+ N+ +C E P C+ +CV G +CRC
Sbjct: 37 QPGVCH---YGTKLACCYGWRR-NSKGVCEATCE-----PGCK-FGECV---GPNKCRCF 83
Query: 139 PGYRLTPSLDECEDVDECGDQ-RICDHGDCRNTIGSYRCECKPGYTLRENV-CRDVDECS 196
PGY +DV+ECG + R C H C NT GSY+C C G+ L + C + C+
Sbjct: 84 PGYTGKTC---SQDVNECGMKPRPCQHR-CVNTHGSYKCFCLSGHMLMPDATCVNSRTCA 139
Query: 197 RPRPVCRNGTCENLPGAYLCHC-DDGFKAGPNN-DCVDVNECREGGMVCR-NGRCRNTVG 253
C+ +CE+ C C G + PN DC+D++EC G ++C N RC NT G
Sbjct: 140 MIN--CQY-SCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFG 196
Query: 254 SFRCECAPGYTLT-ADGR-NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
S+ C+C G+ L GR +C D++EC H C N C NT G ++C C G+K
Sbjct: 197 SYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHAN--CFNTQGSFKCKCKQGYKGN 254
Query: 312 GRRC 315
G RC
Sbjct: 255 GLRC 258
Score = 130 bits (313), Expect = 3e-29
Identities = 73/204 (35%), Positives = 106/204 (51%), Gaps = 21/204 (10%)
Query: 386 ECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNT 445
E C G +G C P+ C G +QD++EC ++P C RCVNT
Sbjct: 62 EATCEPGCKFGE----CVGPNKCR----CFPGYTGKTCSQDVNECGMKPRPCQH-RCVNT 112
Query: 446 DGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQC-SPGFTQGPD 504
GS++C C G++L PD +CV++ CA+ I +C +T G +C C S G P+
Sbjct: 113 HGSYKCFCLSGHMLMPDA-TCVNSRTCAM---INCQYSCEDTEEGPQCLCPSSGLRLAPN 168
Query: 505 -QTCVDVDECAEGRASCTF--RCHNTAGSFRCTCPYGYAV--AADGVHCRDIDECVQEPR 559
+ C+D+DECA G+ C + RC NT GS+ C C G+ + + C DI+EC +
Sbjct: 169 GRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSH 228
Query: 560 VCPH--ACENVVGSYICKCPEGYR 581
C H C N GS+ CKC +GY+
Sbjct: 229 TCSHHANCFNTQGSFKCKCKQGYK 252
Score = 109 bits (263), Expect = 3e-23
Identities = 75/220 (34%), Positives = 105/220 (47%), Gaps = 23/220 (10%)
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECS 196
C G+R S CE E G C G+C +G +C C PGYT + +DV+EC
Sbjct: 49 CCYGWRRN-SKGVCEATCEPG----CKFGEC---VGPNKCRCFPGYT-GKTCSQDVNECG 99
Query: 197 -RPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSF 255
+PRP C++ C N G+Y C C G P+ CV+ C M+ C +T
Sbjct: 100 MKPRP-CQH-RCVNTHGSYKCFCLSGHMLMPDATCVNSRTC---AMINCQYSCEDTEEGP 154
Query: 256 RCEC-APGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV--- 311
+C C + G L +GR+C D+DEC C N C NT G Y C C G++L
Sbjct: 155 QCLCPSSGLRLAPNGRDCLDIDECASGKVICPY--NRRCVNTFGSYYCKCHIGFELQYIS 212
Query: 312 GRR-CVDRDECKELPYVCAG-GECRNFNGGYVCECPAGWR 349
GR C+D +EC + C+ C N G + C+C G++
Sbjct: 213 GRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYK 252
Score = 86.6 bits (205), Expect = 3e-16
Identities = 57/163 (34%), Positives = 76/163 (46%), Gaps = 16/163 (9%)
Query: 479 CGNGTCSNTRGGYECQCSPGFTQGPDQTCV-DVDECAEGRASCTFRCHNTAGSFRCTCPY 537
C G C G +C+C PG+T +TC DV+EC C RC NT GS++C C
Sbjct: 69 CKFGECV---GPNKCRCFPGYT---GKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLS 122
Query: 538 GYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDIN 597
G+ + D C + C C ++CE+ C CP R AP + C DI+
Sbjct: 123 GHMLMPDAT-CVNSRTCAMIN--CQYSCEDTEEGPQCLCPSSGLRL-APNGRD--CLDID 176
Query: 598 ECEEQEDLCS-GGVCINTDGSFLCDCDAGFEPS--EDGTDCID 637
EC + +C C+NT GS+ C C GFE DCID
Sbjct: 177 ECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCID 219
Score = 84.6 bits (200), Expect = 1e-15
Identities = 43/104 (41%), Positives = 58/104 (55%), Gaps = 9/104 (8%)
Query: 764 RCVC-GPGYR--PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGA- 817
+C+C G R P G C D+DECA C ++ C NT GSY C C G+EL
Sbjct: 155 QCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGR 214
Query: 818 -NCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDAC 858
+C D++EC D+HTC C NT+GS++C C+ GY+ G C
Sbjct: 215 YDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRC 258
Score = 81.4 bits (192), Expect = 1e-14
Identities = 47/141 (33%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Query: 82 TCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
+C DT G QC C G C D+DEC+ G+ C +CVN G++ C+C G
Sbjct: 146 SCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIG 205
Query: 141 YRL--TPSLDECEDVDECG-DQRICD-HGDCRNTIGSYRCECKPGYTLRENVCRDVDECS 196
+ L +C D++EC D C H +C NT GS++C+CK GY C + E S
Sbjct: 206 FELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENS 265
Query: 197 RPRPVCRNGTCENLPGAYLCH 217
+ GT ++ L H
Sbjct: 266 VKEVLRAPGTIKDRIKKLLAH 286
Score = 71.3 bits (167), Expect = 1e-11
Identities = 38/93 (40%), Positives = 49/93 (52%), Gaps = 7/93 (7%)
Query: 756 GLCAPGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 814
G C G +C C PGY G+ C+ DV+EC ++P PC C NT GSY C C +G+ L
Sbjct: 72 GECV-GPNKCRCFPGY--TGKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMP 128
Query: 815 DGANCRDVDECERDTHTCQQICSNTEGSYECSC 847
D A C + C CQ C +TE +C C
Sbjct: 129 D-ATCVNSRTCA--MINCQYSCEDTEEGPQCLC 158
Score = 52.0 bits (119), Expect = 9e-06
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 55 GEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTS--HLCRDVD 111
G + P + IDEC +C C +T + C C G+E S + C D++
Sbjct: 162 GLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDIN 221
Query: 112 ECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
EC+ C A C N G+F+C+C GY+
Sbjct: 222 ECTMDSHTCSHHANCFNTQGSFKCKCKQGYK 252
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/107 (33%), Positives = 43/107 (40%), Gaps = 13/107 (12%)
Query: 755 PGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 814
PG+C G C R + VC E + C G C C GY
Sbjct: 38 PGVCHYGTKLACCYGWRRNSKGVCEATCEPGCKFGECV-------GPNKCRCFPGYT--- 87
Query: 815 DGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
G C +DV+EC CQ C NT GSY+C C G+ DA CV
Sbjct: 88 -GKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDATCV 133
Score = 43.2 bits (97), Expect = 0.004
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 16/92 (17%)
Query: 747 DVDECAAIPGLCAPGR--------FRCVCGPGYRP---AGEV-CADVDECAVRPPPCDQ- 793
D+DECA+ +C R + C C G+ +G C D++EC + C
Sbjct: 174 DIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHH 233
Query: 794 -LCHNTDGSYDCLCRTGYELDEDGANCRDVDE 824
C NT GS+ C C+ GY+ +G C + E
Sbjct: 234 ANCFNTQGSFKCKCKQGYK--GNGLRCSAIPE 263
>AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2
precursor protein.
Length = 1285
Score = 130 bits (313), Expect = 3e-29
Identities = 95/283 (33%), Positives = 128/283 (45%), Gaps = 42/283 (14%)
Query: 87 PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPS 146
PTGF+C C G++ D+DEC+ PC A C NL +EC CP GY
Sbjct: 89 PTGFRCYCVPGFQGPRCE---LDIDECA--SRPCHHGATCRNLADRYECHCPLGYAGVT- 142
Query: 147 LDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRN 204
CE +VDEC G C + +GS+RC C PGY C+ D+DEC + +P
Sbjct: 143 ---CEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGY--GGTRCQLDLDEC-QSQPCAHG 196
Query: 205 GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYT 264
GTC +L + C C G + + +V EC N C +GSFRC C PGY+
Sbjct: 197 GTCHDLVNGFRCDCAGTGYEGTHCE-REVLECASAPCE-HNASCLEGLGSFRCLCWPGYS 254
Query: 265 LTADGRNCR-DVDECDELP--H--PCGRDGNPS-------------CTNTNGGYECSCGA 306
G C D DEC P H C + +P+ G+ C C
Sbjct: 255 ----GELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPP 310
Query: 307 GWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
G++ G C V+ DEC P + GG C++ G+ C CP G+
Sbjct: 311 GFE--GADCGVEVDECASRPCL-NGGHCQDLPNGFQCHCPDGY 350
Score = 128 bits (308), Expect = 1e-28
Identities = 119/378 (31%), Positives = 157/378 (41%), Gaps = 46/378 (12%)
Query: 211 PGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCECAPGYTLTADG 269
P + C+C GF+ GP + +D++EC C +G CRN + C C GY G
Sbjct: 89 PTGFRCYCVPGFQ-GPRCE-LDIDEC--ASRPCHHGATCRNLADRYECHCPLGYA----G 140
Query: 270 RNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYV 327
C +VDEC P C G SC + G + C C G+ G RC +D DEC+ P
Sbjct: 141 VTCEMEVDECASAP--CLHGG--SCLDGVGSFRCVCAPGYG--GTRCQLDLDECQSQP-- 192
Query: 328 CA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC-HRARPLQ-LAR 384
CA GG C + G+ C+C AG ++ T ER+ L E + C H A L+ L
Sbjct: 193 CAHGGTCHDLVNGFRCDC-AGTGYEGTHC----EREVL---ECASAPCEHNASCLEGLGS 244
Query: 385 PECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN 444
C C G + G CE + CQ G GR D G
Sbjct: 245 FRCLCWPGYS-GELCE---VDEDECASSPCQHG-GRCLQRSDPALYGGVQAAFPGAFSFR 299
Query: 445 TDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
F C CP G+ +G C V+ DECA P + G G C + G++C C G+ GP
Sbjct: 300 HAAGFLCHCPPGF----EGADCGVEVDECASRPCLNG-GHCQDLPNGFQCHCPDGYA-GP 353
Query: 504 DQTCV-DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDID-ECVQEPRVC 561
TC DVDEC C +T + C CP + V C
Sbjct: 354 --TCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATC 411
Query: 562 PHACENVVGSYICKCPEG 579
E+ V SY+C CP G
Sbjct: 412 IPIFESGVHSYVCHCPPG 429
Score = 118 bits (285), Expect = 7e-26
Identities = 87/287 (30%), Positives = 123/287 (42%), Gaps = 36/287 (12%)
Query: 385 PECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCV 443
P C ++ G C PD F C G P D+DEC RP C G C
Sbjct: 68 PRGCATQPCHHGALCVP-QGPDPTGFRCYCVPGFQGPRCELDIDECASRP--CHHGATCR 124
Query: 444 NTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG 502
N + C CP GY G++C ++ DECA P + G G+C + G + C C+PG+ G
Sbjct: 125 NLADRYECHCPLGYA----GVTCEMEVDECASAPCLHG-GSCLDGVGSFRCVCAPGY--G 177
Query: 503 PDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVC 561
+ +D+DEC + CH+ FRC C +G HC R++ EC P C
Sbjct: 178 GTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA---GTGYEGTHCEREVLECASAP--C 232
Query: 562 PH--ACENVVGSYICKCPEGYRRTSAPQDSENA----CEDINECEEQED-LCSGGVCINT 614
H +C +GS+ C C GY D + C+ C ++ D GGV
Sbjct: 233 EHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAF 292
Query: 615 DGSF--------LCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCE 653
G+F LC C GFE ++ G + + + C L G C+
Sbjct: 293 PGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPC---LNGGHCQ 336
Score = 109 bits (262), Expect = 4e-23
Identities = 102/323 (31%), Positives = 135/323 (41%), Gaps = 57/323 (17%)
Query: 20 KYLCCCSVGHAWGAPCEACPPRGSPA---HTALCGEKPGEY---INPVTNETK---PIDE 70
+Y C C +G+A G CE + A H C + G + P T+ +DE
Sbjct: 129 RYECHCPLGYA-GVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDE 187
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
C P GTCHD GF+C C GYE +H R+V EC+ PC A C+
Sbjct: 188 CQSQP-CAHGGTCHDLVNGFRCDCAGTGYE---GTHCEREVLECA--SAPCEHNASCLEG 241
Query: 130 PGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGD-C-------------------- 167
G+F C C PGY S + CE D DEC C HG C
Sbjct: 242 LGSFRCLCWPGY----SGELCEVDEDECASSP-CQHGGRCLQRSDPALYGGVQAAFPGAF 296
Query: 168 --RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG 225
R+ G + C C PG+ + +VDEC+ RP G C++LP + CHC DG+ AG
Sbjct: 297 SFRHAAG-FLCHCPPGFE-GADCGVEVDECA-SRPCLNGGHCQDLPNGFQCHCPDGY-AG 352
Query: 226 PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHP 284
P + DV+EC + G C +TV + C C T GR+C + C P
Sbjct: 353 PTCE-EDVDECLSDPCL-HGGTCSDTVAGYICRCPE----TWGGRDCSVQLTGCQGHTCP 406
Query: 285 CGRDGNPSCTNTNGGYECSCGAG 307
P + Y C C G
Sbjct: 407 LAATCIPIFESGVHSYVCHCPPG 429
Score = 92.3 bits (219), Expect = 7e-18
Identities = 99/323 (30%), Positives = 130/323 (40%), Gaps = 69/323 (21%)
Query: 361 RKELCYDEWEAGRCHRARPLQ-LA-RPECCCSEGAAWGRYCE----RCP-AP-------- 405
R EL DE + CH + LA R EC C G A G CE C AP
Sbjct: 104 RCELDIDECASRPCHHGATCRNLADRYECHCPLGYA-GVTCEMEVDECASAPCLHGGSCL 162
Query: 406 -DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPD-GYVLAPD 462
F +C G G DLDEC+ +P C GG C + FRC+C GY +
Sbjct: 163 DGVGSFRCVCAPGYGGTRCQLDLDECQSQP--CAHGGTCHDLVNGFRCDCAGTGY----E 216
Query: 463 GLSCV-DADECALDPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRAS 519
G C + ECA P C N +C G + C C PG++ + C VD DECA
Sbjct: 217 GTHCEREVLECASAP--CEHNASCLEGLGSFRCLCWPGYS---GELCEVDEDECASSPCQ 271
Query: 520 CTFRC---------------------HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEP 558
RC A F C CP G+ A GV ++DEC P
Sbjct: 272 HGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGV---EVDECASRP 328
Query: 559 RVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSF 618
+ C+++ + C CP+GY + ED++EC L GG C +T +
Sbjct: 329 CLNGGHCQDLPNGFQCHCPDGYAGPTCE-------EDVDECLSDPCL-HGGTCSDTVAGY 380
Query: 619 LCDCDAGFEPSEDGTDCIDRRTG 641
+C C + G DC + TG
Sbjct: 381 ICRCPETW----GGRDCSVQLTG 399
Score = 74.9 bits (176), Expect = 1e-12
Identities = 67/206 (32%), Positives = 86/206 (41%), Gaps = 49/206 (23%)
Query: 472 CALDPRICGNGT-CSNTR-GGYEC-----------QCSPG---FTQGPDQT-----CV-- 508
CA DP C GT C T GGY C C G QGPD T CV
Sbjct: 42 CASDP--CAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPG 99
Query: 509 --------DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPR 559
D+DECA C N A + C CP GYA GV C ++DEC P
Sbjct: 100 FQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVTCEMEVDECASAPC 155
Query: 560 VCPHACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSF 618
+ +C + VGS+ C C GY T C+ D++EC+ Q GG C + F
Sbjct: 156 LHGGSCLDGVGSFRCVCAPGYGGT--------RCQLDLDECQSQ-PCAHGGTCHDLVNGF 206
Query: 619 LCDC-DAGFEPSEDGTDCIDRRTGTC 643
CDC G+E + + ++ + C
Sbjct: 207 RCDCAGTGYEGTHCEREVLECASAPC 232
Score = 68.5 bits (160), Expect = 9e-11
Identities = 47/121 (38%), Positives = 57/121 (47%), Gaps = 17/121 (14%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+VDECA+ P G C G FRCVC PGY G C D+DEC +P CH+
Sbjct: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGY--GGTRCQLDLDECQSQPCAHGGTCHDLV 203
Query: 800 GSYDCLCR-TGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA 857
+ C C TGYE G +C R+V EC C GS+ C C GY G+
Sbjct: 204 NGFRCDCAGTGYE----GTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYS--GEL 257
Query: 858 C 858
C
Sbjct: 258 C 258
Score = 62.5 bits (145), Expect = 6e-09
Identities = 36/94 (38%), Positives = 43/94 (45%), Gaps = 8/94 (8%)
Query: 760 PGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
P FRC C PG++ G C D+DECA RP C N Y+C C GY G
Sbjct: 89 PTGFRCYCVPGFQ--GPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVT 142
Query: 819 CR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C +VDEC C + GS+ C C GY
Sbjct: 143 CEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGY 176
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/107 (34%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 752 AAIPGLCA---PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRT 808
AA PG + F C C PG+ A + +VDECA RP C + + C C
Sbjct: 290 AAFPGAFSFRHAAGFLCHCPPGFEGA-DCGVEVDECASRPCLNGGHCQDLPNGFQCHCPD 348
Query: 809 GYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
GY G C DVDEC D CS+T Y C C + + R
Sbjct: 349 GYA----GPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGR 391
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/131 (29%), Positives = 52/131 (39%), Gaps = 15/131 (11%)
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG 330
CR C P PC DG +C + + C+CG GW+ G RC D C P CA
Sbjct: 1054 CRGAPVC--APSPCLHDG--ACRDLFDAFACACGPGWE--GPRCEAHVDPCHSAP--CAR 1105
Query: 331 GECRNF-NGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
G C +G + C CP G+ + + L + C P C C
Sbjct: 1106 GRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSP----AANCSC 1161
Query: 390 SEGAAWGRYCE 400
EG A G+ C+
Sbjct: 1162 LEGLA-GQRCQ 1171
Score = 53.2 bits (122), Expect = 4e-06
Identities = 44/144 (30%), Positives = 50/144 (34%), Gaps = 11/144 (7%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLP-GAFECRCPP 139
G C D F C C G+E VD C P RG +C P G FECRCPP
Sbjct: 1069 GACRDLFDAFACACGPGWEGPRCE---AHVDPCH-SAPCARG--RCHTHPDGRFECRCPP 1122
Query: 140 GYRLTPSLDECEDVDECGDQRIC-DHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRP 198
G+ P EC C D C + C C G L C+
Sbjct: 1123 GFG-GPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEG--LAGQRCQVPTLPCEA 1179
Query: 199 RPVCRNGTCENLPGAYLCHCDDGF 222
P GTC G C C+ F
Sbjct: 1180 NPCLNGGTCRAAGGVSECICNARF 1203
Score = 50.4 bits (115), Expect = 3e-05
Identities = 46/161 (28%), Positives = 58/161 (36%), Gaps = 17/161 (10%)
Query: 150 CEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDEC-SRPRPVCRNGTCE 208
C C G CR+ ++ C C PG+ VD C S P C G C
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWE-GPRCEAHVDPCHSAP---CARGRCH 1109
Query: 209 NLP-GAYLCHCDDGFKAGPNNDC-VDVNECREGGMVCRNGR-CRNTVGSFRCECAPGYTL 265
P G + C C GF GP V EC + C +G C + C C G
Sbjct: 1110 THPDGRFECRCPPGF-GGPRCRLPVPSKEC-SLNVTCLDGSPCEGGSPAANCSCLEGLA- 1166
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
G+ C+ V +PC G +C G EC C A
Sbjct: 1167 ---GQRCQ-VPTLPCEANPCLNGG--TCRAAGGVSECICNA 1201
Score = 48.8 bits (111), Expect = 8e-05
Identities = 52/169 (30%), Positives = 66/169 (39%), Gaps = 23/169 (13%)
Query: 464 LSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCT-F 522
L C A CA P + +G C + + C C PG+ +GP + VD C A C
Sbjct: 1052 LGCRGAPVCAPSPCL-HDGACRDLFDAFACACGPGW-EGP-RCEAHVDPCHS--APCARG 1106
Query: 523 RCH-NTAGSFRCTCPYGYAVAADGVHCR---DIDEC-VQEPRVCPHACENVVGSYICKCP 577
RCH + G F C CP G+ G CR EC + + CE + C C
Sbjct: 1107 RCHTHPDGRFECRCPPGFG----GPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCL 1162
Query: 578 EGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
EG Q CE N C +GG C G C C+A F
Sbjct: 1163 EGLAGQRC-QVPTLPCE-ANPC------LNGGTCRAAGGVSECICNARF 1203
Score = 48.4 bits (110), Expect = 1e-04
Identities = 50/157 (31%), Positives = 60/157 (38%), Gaps = 15/157 (9%)
Query: 107 CRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG 165
CR C+ PC C +L AF C C PG+ P CE VD C C G
Sbjct: 1054 CRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE-GP---RCEAHVDPC-HSAPCARG 1106
Query: 166 DCR-NTIGSYRCECKPGY-TLRENVCRDVDECSRPRPVCRNGT-CENLPGAYLCHCDDGF 222
C + G + C C PG+ R + ECS C +G+ CE A C C +G
Sbjct: 1107 RCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSL-NVTCLDGSPCEGGSPAANCSCLEGL 1165
Query: 223 KAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCEC 259
AG V C E G CR G C C
Sbjct: 1166 -AGQRCQ-VPTLPC-EANPCLNGGTCRAAGGVSECIC 1199
Score = 48.0 bits (109), Expect = 1e-04
Identities = 36/131 (27%), Positives = 44/131 (33%), Gaps = 14/131 (10%)
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRC-VNTDGSFRCECPDGYVLAPDGLSCVD 468
F C G P +D C P C GRC + DG F C CP G+ P V
Sbjct: 1078 FACACGPGWEGPRCEAHVDPCHSAP--CARGRCHTHPDGRFECRCPPGFG-GPRCRLPVP 1134
Query: 469 ADECALDPRICGNGTCSNTRGGYECQCSPGFT----QGPDQTCVDVDECAEGRASCTFRC 524
+ EC+L+ C C C G Q P C + + C G C
Sbjct: 1135 SKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC-EANPCLNGGT-----C 1188
Query: 525 HNTAGSFRCTC 535
G C C
Sbjct: 1189 RAAGGVSECIC 1199
Score = 42.7 bits (96), Expect = 0.005
Identities = 37/95 (38%), Positives = 44/95 (46%), Gaps = 15/95 (15%)
Query: 747 DVDECAAIP----GLCAP--GRFRCVC-GPGYRPAGEVCA-DVDECAVRPPPCDQLCHNT 798
D+DEC + P G C FRC C G GY G C +V ECA P + C
Sbjct: 184 DLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYE--GTHCEREVLECASAPCEHNASCLEG 241
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ 833
GS+ CLC GY G C +VDE E + CQ
Sbjct: 242 LGSFRCLCWPGY----SGELC-EVDEDECASSPCQ 271
Score = 39.9 bits (89), Expect = 0.038
Identities = 28/90 (31%), Positives = 35/90 (38%), Gaps = 7/90 (7%)
Query: 416 GGMGRPNLTQD-LDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
GG NLT + E PD C GG C+ T F C CP + G +C C
Sbjct: 794 GGRQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT----GPTCAQQLWCP 849
Query: 474 LDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
P + TC G+ C F +GP
Sbjct: 850 GQPCL-PPATCEEVPDGFVCVAEATFREGP 878
Score = 37.5 bits (83), Expect = 0.20
Identities = 39/139 (28%), Positives = 47/139 (33%), Gaps = 19/139 (13%)
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPN-- 422
C WE RC A + C S A GR C F C G G P
Sbjct: 1082 CGPGWEGPRCE-------AHVDPCHSAPCARGR----CHTHPDGRFECRCPPGFGGPRCR 1130
Query: 423 LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGN 481
L EC + G C + C C +G G C V C +P + G
Sbjct: 1131 LPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLA----GQRCQVPTLPCEANPCLNG- 1185
Query: 482 GTCSNTRGGYECQCSPGFT 500
GTC G EC C+ F+
Sbjct: 1186 GTCRAAGGVSECICNARFS 1204
Score = 36.7 bits (81), Expect = 0.35
Identities = 20/77 (25%), Positives = 29/77 (37%), Gaps = 3/77 (3%)
Query: 150 CEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCEN 209
C D C + G C T + C C +T C C +P TCE
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT--GPTCAQQLWCPG-QPCLPPATCEE 861
Query: 210 LPGAYLCHCDDGFKAGP 226
+P ++C + F+ GP
Sbjct: 862 VPDGFVCVAEATFREGP 878
Score = 36.7 bits (81), Expect = 0.35
Identities = 21/75 (28%), Positives = 28/75 (37%), Gaps = 4/75 (5%)
Query: 507 CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
CV D C+ C T F CTCP + G C C +P + P CE
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT----GPTCAQQLWCPGQPCLPPATCE 860
Query: 567 NVVGSYICKCPEGYR 581
V ++C +R
Sbjct: 861 EVPDGFVCVAEATFR 875
Score = 36.7 bits (81), Expect = 0.35
Identities = 27/100 (27%), Positives = 37/100 (37%), Gaps = 9/100 (9%)
Query: 755 PGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYEL 812
PG R PG C CA P PC D C + ++ C C G+E
Sbjct: 1031 PGAAPGAREHFASWPGTPAPILGCRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE- 1087
Query: 813 DEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C VD C + ++ +G +EC C G+
Sbjct: 1088 ---GPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124
>AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1285
Score = 130 bits (313), Expect = 3e-29
Identities = 95/283 (33%), Positives = 128/283 (45%), Gaps = 42/283 (14%)
Query: 87 PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPS 146
PTGF+C C G++ D+DEC+ PC A C NL +EC CP GY
Sbjct: 89 PTGFRCYCVPGFQGPRCE---LDIDECA--SRPCHHGATCRNLADRYECHCPLGYAGVT- 142
Query: 147 LDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRN 204
CE +VDEC G C + +GS+RC C PGY C+ D+DEC + +P
Sbjct: 143 ---CEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGY--GGTRCQLDLDEC-QSQPCAHG 196
Query: 205 GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYT 264
GTC +L + C C G + + +V EC N C +GSFRC C PGY+
Sbjct: 197 GTCHDLVNGFRCDCAGTGYEGTHCE-REVLECASAPCE-HNASCLEGLGSFRCLCWPGYS 254
Query: 265 LTADGRNCR-DVDECDELP--H--PCGRDGNPS-------------CTNTNGGYECSCGA 306
G C D DEC P H C + +P+ G+ C C
Sbjct: 255 ----GELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPP 310
Query: 307 GWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
G++ G C V+ DEC P + GG C++ G+ C CP G+
Sbjct: 311 GFE--GADCGVEVDECASRPCL-NGGHCQDLPNGFQCHCPDGY 350
Score = 128 bits (308), Expect = 1e-28
Identities = 119/378 (31%), Positives = 157/378 (41%), Gaps = 46/378 (12%)
Query: 211 PGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCECAPGYTLTADG 269
P + C+C GF+ GP + +D++EC C +G CRN + C C GY G
Sbjct: 89 PTGFRCYCVPGFQ-GPRCE-LDIDEC--ASRPCHHGATCRNLADRYECHCPLGYA----G 140
Query: 270 RNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYV 327
C +VDEC P C G SC + G + C C G+ G RC +D DEC+ P
Sbjct: 141 VTCEMEVDECASAP--CLHGG--SCLDGVGSFRCVCAPGYG--GTRCQLDLDECQSQP-- 192
Query: 328 CA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC-HRARPLQ-LAR 384
CA GG C + G+ C+C AG ++ T ER+ L E + C H A L+ L
Sbjct: 193 CAHGGTCHDLVNGFRCDC-AGTGYEGTHC----EREVL---ECASAPCEHNASCLEGLGS 244
Query: 385 PECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN 444
C C G + G CE + CQ G GR D G
Sbjct: 245 FRCLCWPGYS-GELCE---VDEDECASSPCQHG-GRCLQRSDPALYGGVQAAFPGAFSFR 299
Query: 445 TDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
F C CP G+ +G C V+ DECA P + G G C + G++C C G+ GP
Sbjct: 300 HAAGFLCHCPPGF----EGADCGVEVDECASRPCLNG-GHCQDLPNGFQCHCPDGYA-GP 353
Query: 504 DQTCV-DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDID-ECVQEPRVC 561
TC DVDEC C +T + C CP + V C
Sbjct: 354 --TCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATC 411
Query: 562 PHACENVVGSYICKCPEG 579
E+ V SY+C CP G
Sbjct: 412 IPIFESGVHSYVCHCPPG 429
Score = 118 bits (285), Expect = 7e-26
Identities = 87/287 (30%), Positives = 123/287 (42%), Gaps = 36/287 (12%)
Query: 385 PECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCV 443
P C ++ G C PD F C G P D+DEC RP C G C
Sbjct: 68 PRGCATQPCHHGALCVP-QGPDPTGFRCYCVPGFQGPRCELDIDECASRP--CHHGATCR 124
Query: 444 NTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG 502
N + C CP GY G++C ++ DECA P + G G+C + G + C C+PG+ G
Sbjct: 125 NLADRYECHCPLGYA----GVTCEMEVDECASAPCLHG-GSCLDGVGSFRCVCAPGY--G 177
Query: 503 PDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVC 561
+ +D+DEC + CH+ FRC C +G HC R++ EC P C
Sbjct: 178 GTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA---GTGYEGTHCEREVLECASAP--C 232
Query: 562 PH--ACENVVGSYICKCPEGYRRTSAPQDSENA----CEDINECEEQED-LCSGGVCINT 614
H +C +GS+ C C GY D + C+ C ++ D GGV
Sbjct: 233 EHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAF 292
Query: 615 DGSF--------LCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCE 653
G+F LC C GFE ++ G + + + C L G C+
Sbjct: 293 PGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPC---LNGGHCQ 336
Score = 109 bits (262), Expect = 4e-23
Identities = 102/323 (31%), Positives = 135/323 (41%), Gaps = 57/323 (17%)
Query: 20 KYLCCCSVGHAWGAPCEACPPRGSPA---HTALCGEKPGEY---INPVTNETK---PIDE 70
+Y C C +G+A G CE + A H C + G + P T+ +DE
Sbjct: 129 RYECHCPLGYA-GVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDE 187
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
C P GTCHD GF+C C GYE +H R+V EC+ PC A C+
Sbjct: 188 CQSQP-CAHGGTCHDLVNGFRCDCAGTGYE---GTHCEREVLECA--SAPCEHNASCLEG 241
Query: 130 PGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGD-C-------------------- 167
G+F C C PGY S + CE D DEC C HG C
Sbjct: 242 LGSFRCLCWPGY----SGELCEVDEDECASSP-CQHGGRCLQRSDPALYGGVQAAFPGAF 296
Query: 168 --RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG 225
R+ G + C C PG+ + +VDEC+ RP G C++LP + CHC DG+ AG
Sbjct: 297 SFRHAAG-FLCHCPPGFE-GADCGVEVDECA-SRPCLNGGHCQDLPNGFQCHCPDGY-AG 352
Query: 226 PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHP 284
P + DV+EC + G C +TV + C C T GR+C + C P
Sbjct: 353 PTCE-EDVDECLSDPCL-HGGTCSDTVAGYICRCPE----TWGGRDCSVQLTGCQGHTCP 406
Query: 285 CGRDGNPSCTNTNGGYECSCGAG 307
P + Y C C G
Sbjct: 407 LAATCIPIFESGVHSYVCHCPPG 429
Score = 92.3 bits (219), Expect = 7e-18
Identities = 99/323 (30%), Positives = 130/323 (40%), Gaps = 69/323 (21%)
Query: 361 RKELCYDEWEAGRCHRARPLQ-LA-RPECCCSEGAAWGRYCE----RCP-AP-------- 405
R EL DE + CH + LA R EC C G A G CE C AP
Sbjct: 104 RCELDIDECASRPCHHGATCRNLADRYECHCPLGYA-GVTCEMEVDECASAPCLHGGSCL 162
Query: 406 -DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPD-GYVLAPD 462
F +C G G DLDEC+ +P C GG C + FRC+C GY +
Sbjct: 163 DGVGSFRCVCAPGYGGTRCQLDLDECQSQP--CAHGGTCHDLVNGFRCDCAGTGY----E 216
Query: 463 GLSCV-DADECALDPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRAS 519
G C + ECA P C N +C G + C C PG++ + C VD DECA
Sbjct: 217 GTHCEREVLECASAP--CEHNASCLEGLGSFRCLCWPGYS---GELCEVDEDECASSPCQ 271
Query: 520 CTFRC---------------------HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEP 558
RC A F C CP G+ A GV ++DEC P
Sbjct: 272 HGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGV---EVDECASRP 328
Query: 559 RVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSF 618
+ C+++ + C CP+GY + ED++EC L GG C +T +
Sbjct: 329 CLNGGHCQDLPNGFQCHCPDGYAGPTCE-------EDVDECLSDPCL-HGGTCSDTVAGY 380
Query: 619 LCDCDAGFEPSEDGTDCIDRRTG 641
+C C + G DC + TG
Sbjct: 381 ICRCPETW----GGRDCSVQLTG 399
Score = 74.9 bits (176), Expect = 1e-12
Identities = 67/206 (32%), Positives = 86/206 (41%), Gaps = 49/206 (23%)
Query: 472 CALDPRICGNGT-CSNTR-GGYEC-----------QCSPG---FTQGPDQT-----CV-- 508
CA DP C GT C T GGY C C G QGPD T CV
Sbjct: 42 CASDP--CAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPG 99
Query: 509 --------DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPR 559
D+DECA C N A + C CP GYA GV C ++DEC P
Sbjct: 100 FQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVTCEMEVDECASAPC 155
Query: 560 VCPHACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSF 618
+ +C + VGS+ C C GY T C+ D++EC+ Q GG C + F
Sbjct: 156 LHGGSCLDGVGSFRCVCAPGYGGT--------RCQLDLDECQSQ-PCAHGGTCHDLVNGF 206
Query: 619 LCDC-DAGFEPSEDGTDCIDRRTGTC 643
CDC G+E + + ++ + C
Sbjct: 207 RCDCAGTGYEGTHCEREVLECASAPC 232
Score = 68.5 bits (160), Expect = 9e-11
Identities = 47/121 (38%), Positives = 57/121 (47%), Gaps = 17/121 (14%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+VDECA+ P G C G FRCVC PGY G C D+DEC +P CH+
Sbjct: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGY--GGTRCQLDLDECQSQPCAHGGTCHDLV 203
Query: 800 GSYDCLCR-TGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA 857
+ C C TGYE G +C R+V EC C GS+ C C GY G+
Sbjct: 204 NGFRCDCAGTGYE----GTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYS--GEL 257
Query: 858 C 858
C
Sbjct: 258 C 258
Score = 62.5 bits (145), Expect = 6e-09
Identities = 36/94 (38%), Positives = 43/94 (45%), Gaps = 8/94 (8%)
Query: 760 PGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
P FRC C PG++ G C D+DECA RP C N Y+C C GY G
Sbjct: 89 PTGFRCYCVPGFQ--GPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVT 142
Query: 819 CR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C +VDEC C + GS+ C C GY
Sbjct: 143 CEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGY 176
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/107 (34%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 752 AAIPGLCA---PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRT 808
AA PG + F C C PG+ A + +VDECA RP C + + C C
Sbjct: 290 AAFPGAFSFRHAAGFLCHCPPGFEGA-DCGVEVDECASRPCLNGGHCQDLPNGFQCHCPD 348
Query: 809 GYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
GY G C DVDEC D CS+T Y C C + + R
Sbjct: 349 GYA----GPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGR 391
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/131 (29%), Positives = 52/131 (39%), Gaps = 15/131 (11%)
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG 330
CR C P PC DG +C + + C+CG GW+ G RC D C P CA
Sbjct: 1054 CRGAPVC--APSPCLHDG--ACRDLFDAFACACGPGWE--GPRCEAHVDPCHSAP--CAR 1105
Query: 331 GECRNF-NGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
G C +G + C CP G+ + + L + C P C C
Sbjct: 1106 GRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSP----AANCSC 1161
Query: 390 SEGAAWGRYCE 400
EG A G+ C+
Sbjct: 1162 LEGLA-GQRCQ 1171
Score = 53.2 bits (122), Expect = 4e-06
Identities = 44/144 (30%), Positives = 50/144 (34%), Gaps = 11/144 (7%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLP-GAFECRCPP 139
G C D F C C G+E VD C P RG +C P G FECRCPP
Sbjct: 1069 GACRDLFDAFACACGPGWEGPRCE---AHVDPCH-SAPCARG--RCHTHPDGRFECRCPP 1122
Query: 140 GYRLTPSLDECEDVDECGDQRIC-DHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRP 198
G+ P EC C D C + C C G L C+
Sbjct: 1123 GFG-GPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEG--LAGQRCQVPTLPCEA 1179
Query: 199 RPVCRNGTCENLPGAYLCHCDDGF 222
P GTC G C C+ F
Sbjct: 1180 NPCLNGGTCRAAGGVSECICNARF 1203
Score = 50.4 bits (115), Expect = 3e-05
Identities = 46/161 (28%), Positives = 58/161 (36%), Gaps = 17/161 (10%)
Query: 150 CEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDEC-SRPRPVCRNGTCE 208
C C G CR+ ++ C C PG+ VD C S P C G C
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWE-GPRCEAHVDPCHSAP---CARGRCH 1109
Query: 209 NLP-GAYLCHCDDGFKAGPNNDC-VDVNECREGGMVCRNGR-CRNTVGSFRCECAPGYTL 265
P G + C C GF GP V EC + C +G C + C C G
Sbjct: 1110 THPDGRFECRCPPGF-GGPRCRLPVPSKEC-SLNVTCLDGSPCEGGSPAANCSCLEGLA- 1166
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
G+ C+ V +PC G +C G EC C A
Sbjct: 1167 ---GQRCQ-VPTLPCEANPCLNGG--TCRAAGGVSECICNA 1201
Score = 48.8 bits (111), Expect = 8e-05
Identities = 52/169 (30%), Positives = 66/169 (39%), Gaps = 23/169 (13%)
Query: 464 LSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCT-F 522
L C A CA P + +G C + + C C PG+ +GP + VD C A C
Sbjct: 1052 LGCRGAPVCAPSPCL-HDGACRDLFDAFACACGPGW-EGP-RCEAHVDPCHS--APCARG 1106
Query: 523 RCH-NTAGSFRCTCPYGYAVAADGVHCR---DIDEC-VQEPRVCPHACENVVGSYICKCP 577
RCH + G F C CP G+ G CR EC + + CE + C C
Sbjct: 1107 RCHTHPDGRFECRCPPGFG----GPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCL 1162
Query: 578 EGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
EG Q CE N C +GG C G C C+A F
Sbjct: 1163 EGLAGQRC-QVPTLPCE-ANPC------LNGGTCRAAGGVSECICNARF 1203
Score = 48.4 bits (110), Expect = 1e-04
Identities = 50/157 (31%), Positives = 60/157 (38%), Gaps = 15/157 (9%)
Query: 107 CRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG 165
CR C+ PC C +L AF C C PG+ P CE VD C C G
Sbjct: 1054 CRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE-GP---RCEAHVDPC-HSAPCARG 1106
Query: 166 DCR-NTIGSYRCECKPGY-TLRENVCRDVDECSRPRPVCRNGT-CENLPGAYLCHCDDGF 222
C + G + C C PG+ R + ECS C +G+ CE A C C +G
Sbjct: 1107 RCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSL-NVTCLDGSPCEGGSPAANCSCLEGL 1165
Query: 223 KAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCEC 259
AG V C E G CR G C C
Sbjct: 1166 -AGQRCQ-VPTLPC-EANPCLNGGTCRAAGGVSECIC 1199
Score = 48.0 bits (109), Expect = 1e-04
Identities = 36/131 (27%), Positives = 44/131 (33%), Gaps = 14/131 (10%)
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRC-VNTDGSFRCECPDGYVLAPDGLSCVD 468
F C G P +D C P C GRC + DG F C CP G+ P V
Sbjct: 1078 FACACGPGWEGPRCEAHVDPCHSAP--CARGRCHTHPDGRFECRCPPGFG-GPRCRLPVP 1134
Query: 469 ADECALDPRICGNGTCSNTRGGYECQCSPGFT----QGPDQTCVDVDECAEGRASCTFRC 524
+ EC+L+ C C C G Q P C + + C G C
Sbjct: 1135 SKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC-EANPCLNGGT-----C 1188
Query: 525 HNTAGSFRCTC 535
G C C
Sbjct: 1189 RAAGGVSECIC 1199
Score = 42.7 bits (96), Expect = 0.005
Identities = 37/95 (38%), Positives = 44/95 (46%), Gaps = 15/95 (15%)
Query: 747 DVDECAAIP----GLCAP--GRFRCVC-GPGYRPAGEVCA-DVDECAVRPPPCDQLCHNT 798
D+DEC + P G C FRC C G GY G C +V ECA P + C
Sbjct: 184 DLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYE--GTHCEREVLECASAPCEHNASCLEG 241
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ 833
GS+ CLC GY G C +VDE E + CQ
Sbjct: 242 LGSFRCLCWPGY----SGELC-EVDEDECASSPCQ 271
Score = 39.9 bits (89), Expect = 0.038
Identities = 28/90 (31%), Positives = 35/90 (38%), Gaps = 7/90 (7%)
Query: 416 GGMGRPNLTQD-LDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
GG NLT + E PD C GG C+ T F C CP + G +C C
Sbjct: 794 GGRQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT----GPTCAQQLWCP 849
Query: 474 LDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
P + TC G+ C F +GP
Sbjct: 850 GQPCL-PPATCEEVPDGFVCVAEATFREGP 878
Score = 37.5 bits (83), Expect = 0.20
Identities = 39/139 (28%), Positives = 47/139 (33%), Gaps = 19/139 (13%)
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPN-- 422
C WE RC A + C S A GR C F C G G P
Sbjct: 1082 CGPGWEGPRCE-------AHVDPCHSAPCARGR----CHTHPDGRFECRCPPGFGGPRCR 1130
Query: 423 LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGN 481
L EC + G C + C C +G G C V C +P + G
Sbjct: 1131 LPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLA----GQRCQVPTLPCEANPCLNG- 1185
Query: 482 GTCSNTRGGYECQCSPGFT 500
GTC G EC C+ F+
Sbjct: 1186 GTCRAAGGVSECICNARFS 1204
Score = 36.7 bits (81), Expect = 0.35
Identities = 20/77 (25%), Positives = 29/77 (37%), Gaps = 3/77 (3%)
Query: 150 CEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCEN 209
C D C + G C T + C C +T C C +P TCE
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT--GPTCAQQLWCPG-QPCLPPATCEE 861
Query: 210 LPGAYLCHCDDGFKAGP 226
+P ++C + F+ GP
Sbjct: 862 VPDGFVCVAEATFREGP 878
Score = 36.7 bits (81), Expect = 0.35
Identities = 21/75 (28%), Positives = 28/75 (37%), Gaps = 4/75 (5%)
Query: 507 CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
CV D C+ C T F CTCP + G C C +P + P CE
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT----GPTCAQQLWCPGQPCLPPATCE 860
Query: 567 NVVGSYICKCPEGYR 581
V ++C +R
Sbjct: 861 EVPDGFVCVAEATFR 875
Score = 36.7 bits (81), Expect = 0.35
Identities = 27/100 (27%), Positives = 37/100 (37%), Gaps = 9/100 (9%)
Query: 755 PGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYEL 812
PG R PG C CA P PC D C + ++ C C G+E
Sbjct: 1031 PGAAPGAREHFASWPGTPAPILGCRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE- 1087
Query: 813 DEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C VD C + ++ +G +EC C G+
Sbjct: 1088 ---GPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124
>AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1176
Score = 130 bits (313), Expect = 3e-29
Identities = 95/283 (33%), Positives = 128/283 (45%), Gaps = 42/283 (14%)
Query: 87 PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPS 146
PTGF+C C G++ D+DEC+ PC A C NL +EC CP GY
Sbjct: 89 PTGFRCYCVPGFQGPRCE---LDIDECA--SRPCHHGATCRNLADRYECHCPLGYAGVT- 142
Query: 147 LDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRN 204
CE +VDEC G C + +GS+RC C PGY C+ D+DEC + +P
Sbjct: 143 ---CEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGY--GGTRCQLDLDEC-QSQPCAHG 196
Query: 205 GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYT 264
GTC +L + C C G + + +V EC N C +GSFRC C PGY+
Sbjct: 197 GTCHDLVNGFRCDCAGTGYEGTHCE-REVLECASAPCE-HNASCLEGLGSFRCLCWPGYS 254
Query: 265 LTADGRNCR-DVDECDELP--H--PCGRDGNPS-------------CTNTNGGYECSCGA 306
G C D DEC P H C + +P+ G+ C C
Sbjct: 255 ----GELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPP 310
Query: 307 GWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
G++ G C V+ DEC P + GG C++ G+ C CP G+
Sbjct: 311 GFE--GADCGVEVDECASRPCL-NGGHCQDLPNGFQCHCPDGY 350
Score = 128 bits (308), Expect = 1e-28
Identities = 119/378 (31%), Positives = 157/378 (41%), Gaps = 46/378 (12%)
Query: 211 PGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCECAPGYTLTADG 269
P + C+C GF+ GP + +D++EC C +G CRN + C C GY G
Sbjct: 89 PTGFRCYCVPGFQ-GPRCE-LDIDEC--ASRPCHHGATCRNLADRYECHCPLGYA----G 140
Query: 270 RNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYV 327
C +VDEC P C G SC + G + C C G+ G RC +D DEC+ P
Sbjct: 141 VTCEMEVDECASAP--CLHGG--SCLDGVGSFRCVCAPGYG--GTRCQLDLDECQSQP-- 192
Query: 328 CA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC-HRARPLQ-LAR 384
CA GG C + G+ C+C AG ++ T ER+ L E + C H A L+ L
Sbjct: 193 CAHGGTCHDLVNGFRCDC-AGTGYEGTHC----EREVL---ECASAPCEHNASCLEGLGS 244
Query: 385 PECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN 444
C C G + G CE + CQ G GR D G
Sbjct: 245 FRCLCWPGYS-GELCE---VDEDECASSPCQHG-GRCLQRSDPALYGGVQAAFPGAFSFR 299
Query: 445 TDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
F C CP G+ +G C V+ DECA P + G G C + G++C C G+ GP
Sbjct: 300 HAAGFLCHCPPGF----EGADCGVEVDECASRPCLNG-GHCQDLPNGFQCHCPDGYA-GP 353
Query: 504 DQTCV-DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDID-ECVQEPRVC 561
TC DVDEC C +T + C CP + V C
Sbjct: 354 --TCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATC 411
Query: 562 PHACENVVGSYICKCPEG 579
E+ V SY+C CP G
Sbjct: 412 IPIFESGVHSYVCHCPPG 429
Score = 118 bits (285), Expect = 7e-26
Identities = 87/287 (30%), Positives = 123/287 (42%), Gaps = 36/287 (12%)
Query: 385 PECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCV 443
P C ++ G C PD F C G P D+DEC RP C G C
Sbjct: 68 PRGCATQPCHHGALCVP-QGPDPTGFRCYCVPGFQGPRCELDIDECASRP--CHHGATCR 124
Query: 444 NTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG 502
N + C CP GY G++C ++ DECA P + G G+C + G + C C+PG+ G
Sbjct: 125 NLADRYECHCPLGYA----GVTCEMEVDECASAPCLHG-GSCLDGVGSFRCVCAPGY--G 177
Query: 503 PDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVC 561
+ +D+DEC + CH+ FRC C +G HC R++ EC P C
Sbjct: 178 GTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA---GTGYEGTHCEREVLECASAP--C 232
Query: 562 PH--ACENVVGSYICKCPEGYRRTSAPQDSENA----CEDINECEEQED-LCSGGVCINT 614
H +C +GS+ C C GY D + C+ C ++ D GGV
Sbjct: 233 EHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAF 292
Query: 615 DGSF--------LCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCE 653
G+F LC C GFE ++ G + + + C L G C+
Sbjct: 293 PGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPC---LNGGHCQ 336
Score = 109 bits (262), Expect = 4e-23
Identities = 102/323 (31%), Positives = 135/323 (41%), Gaps = 57/323 (17%)
Query: 20 KYLCCCSVGHAWGAPCEACPPRGSPA---HTALCGEKPGEY---INPVTNETK---PIDE 70
+Y C C +G+A G CE + A H C + G + P T+ +DE
Sbjct: 129 RYECHCPLGYA-GVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDE 187
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
C P GTCHD GF+C C GYE +H R+V EC+ PC A C+
Sbjct: 188 CQSQP-CAHGGTCHDLVNGFRCDCAGTGYE---GTHCEREVLECA--SAPCEHNASCLEG 241
Query: 130 PGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGD-C-------------------- 167
G+F C C PGY S + CE D DEC C HG C
Sbjct: 242 LGSFRCLCWPGY----SGELCEVDEDECASSP-CQHGGRCLQRSDPALYGGVQAAFPGAF 296
Query: 168 --RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG 225
R+ G + C C PG+ + +VDEC+ RP G C++LP + CHC DG+ AG
Sbjct: 297 SFRHAAG-FLCHCPPGFE-GADCGVEVDECA-SRPCLNGGHCQDLPNGFQCHCPDGY-AG 352
Query: 226 PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHP 284
P + DV+EC + G C +TV + C C T GR+C + C P
Sbjct: 353 PTCE-EDVDECLSDPCL-HGGTCSDTVAGYICRCPE----TWGGRDCSVQLTGCQGHTCP 406
Query: 285 CGRDGNPSCTNTNGGYECSCGAG 307
P + Y C C G
Sbjct: 407 LAATCIPIFESGVHSYVCHCPPG 429
Score = 92.3 bits (219), Expect = 7e-18
Identities = 99/323 (30%), Positives = 130/323 (40%), Gaps = 69/323 (21%)
Query: 361 RKELCYDEWEAGRCHRARPLQ-LA-RPECCCSEGAAWGRYCE----RCP-AP-------- 405
R EL DE + CH + LA R EC C G A G CE C AP
Sbjct: 104 RCELDIDECASRPCHHGATCRNLADRYECHCPLGYA-GVTCEMEVDECASAPCLHGGSCL 162
Query: 406 -DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPD-GYVLAPD 462
F +C G G DLDEC+ +P C GG C + FRC+C GY +
Sbjct: 163 DGVGSFRCVCAPGYGGTRCQLDLDECQSQP--CAHGGTCHDLVNGFRCDCAGTGY----E 216
Query: 463 GLSCV-DADECALDPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRAS 519
G C + ECA P C N +C G + C C PG++ + C VD DECA
Sbjct: 217 GTHCEREVLECASAP--CEHNASCLEGLGSFRCLCWPGYS---GELCEVDEDECASSPCQ 271
Query: 520 CTFRC---------------------HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEP 558
RC A F C CP G+ A GV ++DEC P
Sbjct: 272 HGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGV---EVDECASRP 328
Query: 559 RVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSF 618
+ C+++ + C CP+GY + ED++EC L GG C +T +
Sbjct: 329 CLNGGHCQDLPNGFQCHCPDGYAGPTCE-------EDVDECLSDPCL-HGGTCSDTVAGY 380
Query: 619 LCDCDAGFEPSEDGTDCIDRRTG 641
+C C + G DC + TG
Sbjct: 381 ICRCPETW----GGRDCSVQLTG 399
Score = 74.9 bits (176), Expect = 1e-12
Identities = 67/206 (32%), Positives = 86/206 (41%), Gaps = 49/206 (23%)
Query: 472 CALDPRICGNGT-CSNTR-GGYEC-----------QCSPG---FTQGPDQT-----CV-- 508
CA DP C GT C T GGY C C G QGPD T CV
Sbjct: 42 CASDP--CAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPG 99
Query: 509 --------DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPR 559
D+DECA C N A + C CP GYA GV C ++DEC P
Sbjct: 100 FQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVTCEMEVDECASAPC 155
Query: 560 VCPHACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSF 618
+ +C + VGS+ C C GY T C+ D++EC+ Q GG C + F
Sbjct: 156 LHGGSCLDGVGSFRCVCAPGYGGT--------RCQLDLDECQSQ-PCAHGGTCHDLVNGF 206
Query: 619 LCDC-DAGFEPSEDGTDCIDRRTGTC 643
CDC G+E + + ++ + C
Sbjct: 207 RCDCAGTGYEGTHCEREVLECASAPC 232
Score = 68.5 bits (160), Expect = 9e-11
Identities = 47/121 (38%), Positives = 57/121 (47%), Gaps = 17/121 (14%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+VDECA+ P G C G FRCVC PGY G C D+DEC +P CH+
Sbjct: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGY--GGTRCQLDLDECQSQPCAHGGTCHDLV 203
Query: 800 GSYDCLCR-TGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA 857
+ C C TGYE G +C R+V EC C GS+ C C GY G+
Sbjct: 204 NGFRCDCAGTGYE----GTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYS--GEL 257
Query: 858 C 858
C
Sbjct: 258 C 258
Score = 62.5 bits (145), Expect = 6e-09
Identities = 36/94 (38%), Positives = 43/94 (45%), Gaps = 8/94 (8%)
Query: 760 PGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
P FRC C PG++ G C D+DECA RP C N Y+C C GY G
Sbjct: 89 PTGFRCYCVPGFQ--GPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVT 142
Query: 819 CR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C +VDEC C + GS+ C C GY
Sbjct: 143 CEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGY 176
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/107 (34%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 752 AAIPGLCA---PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRT 808
AA PG + F C C PG+ A + +VDECA RP C + + C C
Sbjct: 290 AAFPGAFSFRHAAGFLCHCPPGFEGA-DCGVEVDECASRPCLNGGHCQDLPNGFQCHCPD 348
Query: 809 GYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
GY G C DVDEC D CS+T Y C C + + R
Sbjct: 349 GYA----GPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGR 391
Score = 43.2 bits (97), Expect = 0.004
Identities = 31/88 (35%), Positives = 40/88 (45%), Gaps = 11/88 (12%)
Query: 464 LSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF- 522
L C A CA P + +G C + + C C PG+ +GP + VD C A C
Sbjct: 1052 LGCRGAPVCAPSPCL-HDGACRDLFDAFACACGPGW-EGP-RCEAHVDPCHS--APCARG 1106
Query: 523 RCH-NTAGSFRCTCPYGYAVAADGVHCR 549
RCH + G F C CP G+ G CR
Sbjct: 1107 RCHTHPDGRFECRCPPGFG----GPRCR 1130
Score = 42.7 bits (96), Expect = 0.005
Identities = 37/95 (38%), Positives = 44/95 (46%), Gaps = 15/95 (15%)
Query: 747 DVDECAAIP----GLCAP--GRFRCVC-GPGYRPAGEVCA-DVDECAVRPPPCDQLCHNT 798
D+DEC + P G C FRC C G GY G C +V ECA P + C
Sbjct: 184 DLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYE--GTHCEREVLECASAPCEHNASCLEG 241
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ 833
GS+ CLC GY G C +VDE E + CQ
Sbjct: 242 LGSFRCLCWPGY----SGELC-EVDEDECASSPCQ 271
Score = 42.7 bits (96), Expect = 0.005
Identities = 25/62 (40%), Positives = 28/62 (45%), Gaps = 7/62 (11%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLP-GAFECRCPP 139
G C D F C C G+E VD C P RG +C P G FECRCPP
Sbjct: 1069 GACRDLFDAFACACGPGWEGPRCE---AHVDPCH-SAPCARG--RCHTHPDGRFECRCPP 1122
Query: 140 GY 141
G+
Sbjct: 1123 GF 1124
Score = 40.3 bits (90), Expect = 0.028
Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 11/72 (15%)
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECS 303
+G CR+ +F C C PG+ +G C VD C P GR T+ +G +EC
Sbjct: 1068 DGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAPCARGR----CHTHPDGRFECR 1119
Query: 304 CGAGWKLVGRRC 315
C G+ G RC
Sbjct: 1120 CPPGFG--GPRC 1129
Score = 39.9 bits (89), Expect = 0.038
Identities = 28/90 (31%), Positives = 35/90 (38%), Gaps = 7/90 (7%)
Query: 416 GGMGRPNLTQD-LDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
GG NLT + E PD C GG C+ T F C CP + G +C C
Sbjct: 794 GGRQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT----GPTCAQQLWCP 849
Query: 474 LDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
P + TC G+ C F +GP
Sbjct: 850 GQPCL-PPATCEEVPDGFVCVAEATFREGP 878
Score = 39.1 bits (87), Expect = 0.066
Identities = 25/79 (31%), Positives = 30/79 (37%), Gaps = 7/79 (8%)
Query: 150 CEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDEC-SRPRPVCRNGTCE 208
C C G CR+ ++ C C PG+ VD C S P C G C
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWE-GPRCEAHVDPCHSAP---CARGRCH 1109
Query: 209 NLP-GAYLCHCDDGFKAGP 226
P G + C C GF GP
Sbjct: 1110 THPDGRFECRCPPGF-GGP 1127
Score = 39.1 bits (87), Expect = 0.066
Identities = 27/78 (34%), Positives = 33/78 (42%), Gaps = 9/78 (11%)
Query: 107 CRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG 165
CR C+ PC C +L AF C C PG+ P CE VD C C G
Sbjct: 1054 CRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE-GP---RCEAHVDPC-HSAPCARG 1106
Query: 166 DCR-NTIGSYRCECKPGY 182
C + G + C C PG+
Sbjct: 1107 RCHTHPDGRFECRCPPGF 1124
Score = 37.9 bits (84), Expect = 0.15
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 9/69 (13%)
Query: 434 PDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTC-SNTRGG 490
P C+ G C + +F C C G+ +G C D C P C G C ++ G
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAP--CARGRCHTHPDGR 1115
Query: 491 YECQCSPGF 499
+EC+C PGF
Sbjct: 1116 FECRCPPGF 1124
Score = 37.1 bits (82), Expect = 0.27
Identities = 18/49 (36%), Positives = 21/49 (42%), Gaps = 3/49 (6%)
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRC-VNTDGSFRCECPDGY 457
F C G P +D C P C GRC + DG F C CP G+
Sbjct: 1078 FACACGPGWEGPRCEAHVDPCHSAP--CARGRCHTHPDGRFECRCPPGF 1124
Score = 36.7 bits (81), Expect = 0.35
Identities = 20/77 (25%), Positives = 29/77 (37%), Gaps = 3/77 (3%)
Query: 150 CEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCEN 209
C D C + G C T + C C +T C C +P TCE
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT--GPTCAQQLWCPG-QPCLPPATCEE 861
Query: 210 LPGAYLCHCDDGFKAGP 226
+P ++C + F+ GP
Sbjct: 862 VPDGFVCVAEATFREGP 878
Score = 36.7 bits (81), Expect = 0.35
Identities = 21/75 (28%), Positives = 28/75 (37%), Gaps = 4/75 (5%)
Query: 507 CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
CV D C+ C T F CTCP + G C C +P + P CE
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT----GPTCAQQLWCPGQPCLPPATCE 860
Query: 567 NVVGSYICKCPEGYR 581
V ++C +R
Sbjct: 861 EVPDGFVCVAEATFR 875
Score = 36.7 bits (81), Expect = 0.35
Identities = 27/100 (27%), Positives = 37/100 (37%), Gaps = 9/100 (9%)
Query: 755 PGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYEL 812
PG R PG C CA P PC D C + ++ C C G+E
Sbjct: 1031 PGAAPGAREHFASWPGTPAPILGCRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE- 1087
Query: 813 DEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C VD C + ++ +G +EC C G+
Sbjct: 1088 ---GPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124
Score = 34.3 bits (75), Expect = 1.9
Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 12/81 (14%)
Query: 548 CRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLC 606
CR C P + AC ++ ++ C C G+ P+ CE ++ C C
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGW---EGPR-----CEAHVDPCHSAP--C 1103
Query: 607 SGGVC-INTDGSFLCDCDAGF 626
+ G C + DG F C C GF
Sbjct: 1104 ARGRCHTHPDGRFECRCPPGF 1124
>AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1285
Score = 130 bits (313), Expect = 3e-29
Identities = 95/283 (33%), Positives = 128/283 (45%), Gaps = 42/283 (14%)
Query: 87 PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPS 146
PTGF+C C G++ D+DEC+ PC A C NL +EC CP GY
Sbjct: 89 PTGFRCYCVPGFQGPRCE---LDIDECA--SRPCHHGATCRNLADRYECHCPLGYAGVT- 142
Query: 147 LDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRN 204
CE +VDEC G C + +GS+RC C PGY C+ D+DEC + +P
Sbjct: 143 ---CEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGY--GGTRCQLDLDEC-QSQPCAHG 196
Query: 205 GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYT 264
GTC +L + C C G + + +V EC N C +GSFRC C PGY+
Sbjct: 197 GTCHDLVNGFRCDCAGTGYEGTHCE-REVLECASAPCE-HNASCLEGLGSFRCLCWPGYS 254
Query: 265 LTADGRNCR-DVDECDELP--H--PCGRDGNPS-------------CTNTNGGYECSCGA 306
G C D DEC P H C + +P+ G+ C C
Sbjct: 255 ----GELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPP 310
Query: 307 GWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
G++ G C V+ DEC P + GG C++ G+ C CP G+
Sbjct: 311 GFE--GADCGVEVDECASRPCL-NGGHCQDLPNGFQCHCPDGY 350
Score = 128 bits (308), Expect = 1e-28
Identities = 119/378 (31%), Positives = 157/378 (41%), Gaps = 46/378 (12%)
Query: 211 PGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCECAPGYTLTADG 269
P + C+C GF+ GP + +D++EC C +G CRN + C C GY G
Sbjct: 89 PTGFRCYCVPGFQ-GPRCE-LDIDEC--ASRPCHHGATCRNLADRYECHCPLGYA----G 140
Query: 270 RNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYV 327
C +VDEC P C G SC + G + C C G+ G RC +D DEC+ P
Sbjct: 141 VTCEMEVDECASAP--CLHGG--SCLDGVGSFRCVCAPGYG--GTRCQLDLDECQSQP-- 192
Query: 328 CA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC-HRARPLQ-LAR 384
CA GG C + G+ C+C AG ++ T ER+ L E + C H A L+ L
Sbjct: 193 CAHGGTCHDLVNGFRCDC-AGTGYEGTHC----EREVL---ECASAPCEHNASCLEGLGS 244
Query: 385 PECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN 444
C C G + G CE + CQ G GR D G
Sbjct: 245 FRCLCWPGYS-GELCE---VDEDECASSPCQHG-GRCLQRSDPALYGGVQAAFPGAFSFR 299
Query: 445 TDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
F C CP G+ +G C V+ DECA P + G G C + G++C C G+ GP
Sbjct: 300 HAAGFLCHCPPGF----EGADCGVEVDECASRPCLNG-GHCQDLPNGFQCHCPDGYA-GP 353
Query: 504 DQTCV-DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDID-ECVQEPRVC 561
TC DVDEC C +T + C CP + V C
Sbjct: 354 --TCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATC 411
Query: 562 PHACENVVGSYICKCPEG 579
E+ V SY+C CP G
Sbjct: 412 IPIFESGVHSYVCHCPPG 429
Score = 118 bits (285), Expect = 7e-26
Identities = 87/287 (30%), Positives = 123/287 (42%), Gaps = 36/287 (12%)
Query: 385 PECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCV 443
P C ++ G C PD F C G P D+DEC RP C G C
Sbjct: 68 PRGCATQPCHHGALCVP-QGPDPTGFRCYCVPGFQGPRCELDIDECASRP--CHHGATCR 124
Query: 444 NTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG 502
N + C CP GY G++C ++ DECA P + G G+C + G + C C+PG+ G
Sbjct: 125 NLADRYECHCPLGYA----GVTCEMEVDECASAPCLHG-GSCLDGVGSFRCVCAPGY--G 177
Query: 503 PDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVC 561
+ +D+DEC + CH+ FRC C +G HC R++ EC P C
Sbjct: 178 GTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA---GTGYEGTHCEREVLECASAP--C 232
Query: 562 PH--ACENVVGSYICKCPEGYRRTSAPQDSENA----CEDINECEEQED-LCSGGVCINT 614
H +C +GS+ C C GY D + C+ C ++ D GGV
Sbjct: 233 EHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAF 292
Query: 615 DGSF--------LCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCE 653
G+F LC C GFE ++ G + + + C L G C+
Sbjct: 293 PGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPC---LNGGHCQ 336
Score = 109 bits (262), Expect = 4e-23
Identities = 102/323 (31%), Positives = 135/323 (41%), Gaps = 57/323 (17%)
Query: 20 KYLCCCSVGHAWGAPCEACPPRGSPA---HTALCGEKPGEY---INPVTNETK---PIDE 70
+Y C C +G+A G CE + A H C + G + P T+ +DE
Sbjct: 129 RYECHCPLGYA-GVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDE 187
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
C P GTCHD GF+C C GYE +H R+V EC+ PC A C+
Sbjct: 188 CQSQP-CAHGGTCHDLVNGFRCDCAGTGYE---GTHCEREVLECA--SAPCEHNASCLEG 241
Query: 130 PGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGD-C-------------------- 167
G+F C C PGY S + CE D DEC C HG C
Sbjct: 242 LGSFRCLCWPGY----SGELCEVDEDECASSP-CQHGGRCLQRSDPALYGGVQAAFPGAF 296
Query: 168 --RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG 225
R+ G + C C PG+ + +VDEC+ RP G C++LP + CHC DG+ AG
Sbjct: 297 SFRHAAG-FLCHCPPGFE-GADCGVEVDECA-SRPCLNGGHCQDLPNGFQCHCPDGY-AG 352
Query: 226 PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHP 284
P + DV+EC + G C +TV + C C T GR+C + C P
Sbjct: 353 PTCE-EDVDECLSDPCL-HGGTCSDTVAGYICRCPE----TWGGRDCSVQLTGCQGHTCP 406
Query: 285 CGRDGNPSCTNTNGGYECSCGAG 307
P + Y C C G
Sbjct: 407 LAATCIPIFESGVHSYVCHCPPG 429
Score = 92.3 bits (219), Expect = 7e-18
Identities = 99/323 (30%), Positives = 130/323 (40%), Gaps = 69/323 (21%)
Query: 361 RKELCYDEWEAGRCHRARPLQ-LA-RPECCCSEGAAWGRYCE----RCP-AP-------- 405
R EL DE + CH + LA R EC C G A G CE C AP
Sbjct: 104 RCELDIDECASRPCHHGATCRNLADRYECHCPLGYA-GVTCEMEVDECASAPCLHGGSCL 162
Query: 406 -DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPD-GYVLAPD 462
F +C G G DLDEC+ +P C GG C + FRC+C GY +
Sbjct: 163 DGVGSFRCVCAPGYGGTRCQLDLDECQSQP--CAHGGTCHDLVNGFRCDCAGTGY----E 216
Query: 463 GLSCV-DADECALDPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRAS 519
G C + ECA P C N +C G + C C PG++ + C VD DECA
Sbjct: 217 GTHCEREVLECASAP--CEHNASCLEGLGSFRCLCWPGYS---GELCEVDEDECASSPCQ 271
Query: 520 CTFRC---------------------HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEP 558
RC A F C CP G+ A GV ++DEC P
Sbjct: 272 HGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGV---EVDECASRP 328
Query: 559 RVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSF 618
+ C+++ + C CP+GY + ED++EC L GG C +T +
Sbjct: 329 CLNGGHCQDLPNGFQCHCPDGYAGPTCE-------EDVDECLSDPCL-HGGTCSDTVAGY 380
Query: 619 LCDCDAGFEPSEDGTDCIDRRTG 641
+C C + G DC + TG
Sbjct: 381 ICRCPETW----GGRDCSVQLTG 399
Score = 74.9 bits (176), Expect = 1e-12
Identities = 67/206 (32%), Positives = 86/206 (41%), Gaps = 49/206 (23%)
Query: 472 CALDPRICGNGT-CSNTR-GGYEC-----------QCSPG---FTQGPDQT-----CV-- 508
CA DP C GT C T GGY C C G QGPD T CV
Sbjct: 42 CASDP--CAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPG 99
Query: 509 --------DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPR 559
D+DECA C N A + C CP GYA GV C ++DEC P
Sbjct: 100 FQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVTCEMEVDECASAPC 155
Query: 560 VCPHACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSF 618
+ +C + VGS+ C C GY T C+ D++EC+ Q GG C + F
Sbjct: 156 LHGGSCLDGVGSFRCVCAPGYGGT--------RCQLDLDECQSQ-PCAHGGTCHDLVNGF 206
Query: 619 LCDC-DAGFEPSEDGTDCIDRRTGTC 643
CDC G+E + + ++ + C
Sbjct: 207 RCDCAGTGYEGTHCEREVLECASAPC 232
Score = 68.5 bits (160), Expect = 9e-11
Identities = 47/121 (38%), Positives = 57/121 (47%), Gaps = 17/121 (14%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+VDECA+ P G C G FRCVC PGY G C D+DEC +P CH+
Sbjct: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGY--GGTRCQLDLDECQSQPCAHGGTCHDLV 203
Query: 800 GSYDCLCR-TGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA 857
+ C C TGYE G +C R+V EC C GS+ C C GY G+
Sbjct: 204 NGFRCDCAGTGYE----GTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYS--GEL 257
Query: 858 C 858
C
Sbjct: 258 C 258
Score = 62.5 bits (145), Expect = 6e-09
Identities = 36/94 (38%), Positives = 43/94 (45%), Gaps = 8/94 (8%)
Query: 760 PGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
P FRC C PG++ G C D+DECA RP C N Y+C C GY G
Sbjct: 89 PTGFRCYCVPGFQ--GPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVT 142
Query: 819 CR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C +VDEC C + GS+ C C GY
Sbjct: 143 CEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGY 176
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/107 (34%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 752 AAIPGLCA---PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRT 808
AA PG + F C C PG+ A + +VDECA RP C + + C C
Sbjct: 290 AAFPGAFSFRHAAGFLCHCPPGFEGA-DCGVEVDECASRPCLNGGHCQDLPNGFQCHCPD 348
Query: 809 GYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
GY G C DVDEC D CS+T Y C C + + R
Sbjct: 349 GYA----GPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGR 391
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/131 (29%), Positives = 52/131 (39%), Gaps = 15/131 (11%)
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG 330
CR C P PC DG +C + + C+CG GW+ G RC D C P CA
Sbjct: 1054 CRGAPVC--APSPCLHDG--ACRDLFDAFACACGPGWE--GPRCEAHVDPCHSAP--CAR 1105
Query: 331 GECRNF-NGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
G C +G + C CP G+ + + L + C P C C
Sbjct: 1106 GRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSP----AANCSC 1161
Query: 390 SEGAAWGRYCE 400
EG A G+ C+
Sbjct: 1162 LEGLA-GQRCQ 1171
Score = 53.2 bits (122), Expect = 4e-06
Identities = 44/144 (30%), Positives = 50/144 (34%), Gaps = 11/144 (7%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLP-GAFECRCPP 139
G C D F C C G+E VD C P RG +C P G FECRCPP
Sbjct: 1069 GACRDLFDAFACACGPGWEGPRCE---AHVDPCH-SAPCARG--RCHTHPDGRFECRCPP 1122
Query: 140 GYRLTPSLDECEDVDECGDQRIC-DHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRP 198
G+ P EC C D C + C C G L C+
Sbjct: 1123 GFG-GPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEG--LAGQRCQVPTLPCEA 1179
Query: 199 RPVCRNGTCENLPGAYLCHCDDGF 222
P GTC G C C+ F
Sbjct: 1180 NPCLNGGTCRAAGGVSECICNARF 1203
Score = 50.4 bits (115), Expect = 3e-05
Identities = 46/161 (28%), Positives = 58/161 (36%), Gaps = 17/161 (10%)
Query: 150 CEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDEC-SRPRPVCRNGTCE 208
C C G CR+ ++ C C PG+ VD C S P C G C
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWE-GPRCEAHVDPCHSAP---CARGRCH 1109
Query: 209 NLP-GAYLCHCDDGFKAGPNNDC-VDVNECREGGMVCRNGR-CRNTVGSFRCECAPGYTL 265
P G + C C GF GP V EC + C +G C + C C G
Sbjct: 1110 THPDGRFECRCPPGF-GGPRCRLPVPSKEC-SLNVTCLDGSPCEGGSPAANCSCLEGLA- 1166
Query: 266 TADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
G+ C+ V +PC G +C G EC C A
Sbjct: 1167 ---GQRCQ-VPTLPCEANPCLNGG--TCRAAGGVSECICNA 1201
Score = 48.8 bits (111), Expect = 8e-05
Identities = 52/169 (30%), Positives = 66/169 (39%), Gaps = 23/169 (13%)
Query: 464 LSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCT-F 522
L C A CA P + +G C + + C C PG+ +GP + VD C A C
Sbjct: 1052 LGCRGAPVCAPSPCL-HDGACRDLFDAFACACGPGW-EGP-RCEAHVDPCHS--APCARG 1106
Query: 523 RCH-NTAGSFRCTCPYGYAVAADGVHCR---DIDEC-VQEPRVCPHACENVVGSYICKCP 577
RCH + G F C CP G+ G CR EC + + CE + C C
Sbjct: 1107 RCHTHPDGRFECRCPPGFG----GPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCL 1162
Query: 578 EGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
EG Q CE N C +GG C G C C+A F
Sbjct: 1163 EGLAGQRC-QVPTLPCE-ANPC------LNGGTCRAAGGVSECICNARF 1203
Score = 48.4 bits (110), Expect = 1e-04
Identities = 50/157 (31%), Positives = 60/157 (38%), Gaps = 15/157 (9%)
Query: 107 CRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG 165
CR C+ PC C +L AF C C PG+ P CE VD C C G
Sbjct: 1054 CRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE-GP---RCEAHVDPC-HSAPCARG 1106
Query: 166 DCR-NTIGSYRCECKPGY-TLRENVCRDVDECSRPRPVCRNGT-CENLPGAYLCHCDDGF 222
C + G + C C PG+ R + ECS C +G+ CE A C C +G
Sbjct: 1107 RCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSL-NVTCLDGSPCEGGSPAANCSCLEGL 1165
Query: 223 KAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCEC 259
AG V C E G CR G C C
Sbjct: 1166 -AGQRCQ-VPTLPC-EANPCLNGGTCRAAGGVSECIC 1199
Score = 48.0 bits (109), Expect = 1e-04
Identities = 36/131 (27%), Positives = 44/131 (33%), Gaps = 14/131 (10%)
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRC-VNTDGSFRCECPDGYVLAPDGLSCVD 468
F C G P +D C P C GRC + DG F C CP G+ P V
Sbjct: 1078 FACACGPGWEGPRCEAHVDPCHSAP--CARGRCHTHPDGRFECRCPPGFG-GPRCRLPVP 1134
Query: 469 ADECALDPRICGNGTCSNTRGGYECQCSPGFT----QGPDQTCVDVDECAEGRASCTFRC 524
+ EC+L+ C C C G Q P C + + C G C
Sbjct: 1135 SKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC-EANPCLNGGT-----C 1188
Query: 525 HNTAGSFRCTC 535
G C C
Sbjct: 1189 RAAGGVSECIC 1199
Score = 42.7 bits (96), Expect = 0.005
Identities = 37/95 (38%), Positives = 44/95 (46%), Gaps = 15/95 (15%)
Query: 747 DVDECAAIP----GLCAP--GRFRCVC-GPGYRPAGEVCA-DVDECAVRPPPCDQLCHNT 798
D+DEC + P G C FRC C G GY G C +V ECA P + C
Sbjct: 184 DLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYE--GTHCEREVLECASAPCEHNASCLEG 241
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ 833
GS+ CLC GY G C +VDE E + CQ
Sbjct: 242 LGSFRCLCWPGY----SGELC-EVDEDECASSPCQ 271
Score = 39.9 bits (89), Expect = 0.038
Identities = 28/90 (31%), Positives = 35/90 (38%), Gaps = 7/90 (7%)
Query: 416 GGMGRPNLTQD-LDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
GG NLT + E PD C GG C+ T F C CP + G +C C
Sbjct: 794 GGRQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT----GPTCAQQLWCP 849
Query: 474 LDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
P + TC G+ C F +GP
Sbjct: 850 GQPCL-PPATCEEVPDGFVCVAEATFREGP 878
Score = 37.5 bits (83), Expect = 0.20
Identities = 39/139 (28%), Positives = 47/139 (33%), Gaps = 19/139 (13%)
Query: 365 CYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPN-- 422
C WE RC A + C S A GR C F C G G P
Sbjct: 1082 CGPGWEGPRCE-------AHVDPCHSAPCARGR----CHTHPDGRFECRCPPGFGGPRCR 1130
Query: 423 LTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGN 481
L EC + G C + C C +G G C V C +P + G
Sbjct: 1131 LPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLA----GQRCQVPTLPCEANPCLNG- 1185
Query: 482 GTCSNTRGGYECQCSPGFT 500
GTC G EC C+ F+
Sbjct: 1186 GTCRAAGGVSECICNARFS 1204
Score = 36.7 bits (81), Expect = 0.35
Identities = 20/77 (25%), Positives = 29/77 (37%), Gaps = 3/77 (3%)
Query: 150 CEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCEN 209
C D C + G C T + C C +T C C +P TCE
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT--GPTCAQQLWCPG-QPCLPPATCEE 861
Query: 210 LPGAYLCHCDDGFKAGP 226
+P ++C + F+ GP
Sbjct: 862 VPDGFVCVAEATFREGP 878
Score = 36.7 bits (81), Expect = 0.35
Identities = 21/75 (28%), Positives = 28/75 (37%), Gaps = 4/75 (5%)
Query: 507 CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
CV D C+ C T F CTCP + G C C +P + P CE
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT----GPTCAQQLWCPGQPCLPPATCE 860
Query: 567 NVVGSYICKCPEGYR 581
V ++C +R
Sbjct: 861 EVPDGFVCVAEATFR 875
Score = 36.7 bits (81), Expect = 0.35
Identities = 27/100 (27%), Positives = 37/100 (37%), Gaps = 9/100 (9%)
Query: 755 PGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYEL 812
PG R PG C CA P PC D C + ++ C C G+E
Sbjct: 1031 PGAAPGAREHFASWPGTPAPILGCRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE- 1087
Query: 813 DEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C VD C + ++ +G +EC C G+
Sbjct: 1088 ---GPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124
>AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1176
Score = 130 bits (313), Expect = 3e-29
Identities = 95/283 (33%), Positives = 128/283 (45%), Gaps = 42/283 (14%)
Query: 87 PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPS 146
PTGF+C C G++ D+DEC+ PC A C NL +EC CP GY
Sbjct: 89 PTGFRCYCVPGFQGPRCE---LDIDECA--SRPCHHGATCRNLADRYECHCPLGYAGVT- 142
Query: 147 LDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRN 204
CE +VDEC G C + +GS+RC C PGY C+ D+DEC + +P
Sbjct: 143 ---CEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGY--GGTRCQLDLDEC-QSQPCAHG 196
Query: 205 GTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYT 264
GTC +L + C C G + + +V EC N C +GSFRC C PGY+
Sbjct: 197 GTCHDLVNGFRCDCAGTGYEGTHCE-REVLECASAPCE-HNASCLEGLGSFRCLCWPGYS 254
Query: 265 LTADGRNCR-DVDECDELP--H--PCGRDGNPS-------------CTNTNGGYECSCGA 306
G C D DEC P H C + +P+ G+ C C
Sbjct: 255 ----GELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPP 310
Query: 307 GWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
G++ G C V+ DEC P + GG C++ G+ C CP G+
Sbjct: 311 GFE--GADCGVEVDECASRPCL-NGGHCQDLPNGFQCHCPDGY 350
Score = 128 bits (308), Expect = 1e-28
Identities = 119/378 (31%), Positives = 157/378 (41%), Gaps = 46/378 (12%)
Query: 211 PGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCECAPGYTLTADG 269
P + C+C GF+ GP + +D++EC C +G CRN + C C GY G
Sbjct: 89 PTGFRCYCVPGFQ-GPRCE-LDIDEC--ASRPCHHGATCRNLADRYECHCPLGYA----G 140
Query: 270 RNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYV 327
C +VDEC P C G SC + G + C C G+ G RC +D DEC+ P
Sbjct: 141 VTCEMEVDECASAP--CLHGG--SCLDGVGSFRCVCAPGYG--GTRCQLDLDECQSQP-- 192
Query: 328 CA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC-HRARPLQ-LAR 384
CA GG C + G+ C+C AG ++ T ER+ L E + C H A L+ L
Sbjct: 193 CAHGGTCHDLVNGFRCDC-AGTGYEGTHC----EREVL---ECASAPCEHNASCLEGLGS 244
Query: 385 PECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN 444
C C G + G CE + CQ G GR D G
Sbjct: 245 FRCLCWPGYS-GELCE---VDEDECASSPCQHG-GRCLQRSDPALYGGVQAAFPGAFSFR 299
Query: 445 TDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
F C CP G+ +G C V+ DECA P + G G C + G++C C G+ GP
Sbjct: 300 HAAGFLCHCPPGF----EGADCGVEVDECASRPCLNG-GHCQDLPNGFQCHCPDGYA-GP 353
Query: 504 DQTCV-DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDID-ECVQEPRVC 561
TC DVDEC C +T + C CP + V C
Sbjct: 354 --TCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATC 411
Query: 562 PHACENVVGSYICKCPEG 579
E+ V SY+C CP G
Sbjct: 412 IPIFESGVHSYVCHCPPG 429
Score = 118 bits (285), Expect = 7e-26
Identities = 87/287 (30%), Positives = 123/287 (42%), Gaps = 36/287 (12%)
Query: 385 PECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCV 443
P C ++ G C PD F C G P D+DEC RP C G C
Sbjct: 68 PRGCATQPCHHGALCVP-QGPDPTGFRCYCVPGFQGPRCELDIDECASRP--CHHGATCR 124
Query: 444 NTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG 502
N + C CP GY G++C ++ DECA P + G G+C + G + C C+PG+ G
Sbjct: 125 NLADRYECHCPLGYA----GVTCEMEVDECASAPCLHG-GSCLDGVGSFRCVCAPGY--G 177
Query: 503 PDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVC 561
+ +D+DEC + CH+ FRC C +G HC R++ EC P C
Sbjct: 178 GTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA---GTGYEGTHCEREVLECASAP--C 232
Query: 562 PH--ACENVVGSYICKCPEGYRRTSAPQDSENA----CEDINECEEQED-LCSGGVCINT 614
H +C +GS+ C C GY D + C+ C ++ D GGV
Sbjct: 233 EHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAF 292
Query: 615 DGSF--------LCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCE 653
G+F LC C GFE ++ G + + + C L G C+
Sbjct: 293 PGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPC---LNGGHCQ 336
Score = 109 bits (262), Expect = 4e-23
Identities = 102/323 (31%), Positives = 135/323 (41%), Gaps = 57/323 (17%)
Query: 20 KYLCCCSVGHAWGAPCEACPPRGSPA---HTALCGEKPGEY---INPVTNETK---PIDE 70
+Y C C +G+A G CE + A H C + G + P T+ +DE
Sbjct: 129 RYECHCPLGYA-GVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDE 187
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
C P GTCHD GF+C C GYE +H R+V EC+ PC A C+
Sbjct: 188 CQSQP-CAHGGTCHDLVNGFRCDCAGTGYE---GTHCEREVLECA--SAPCEHNASCLEG 241
Query: 130 PGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGD-C-------------------- 167
G+F C C PGY S + CE D DEC C HG C
Sbjct: 242 LGSFRCLCWPGY----SGELCEVDEDECASSP-CQHGGRCLQRSDPALYGGVQAAFPGAF 296
Query: 168 --RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG 225
R+ G + C C PG+ + +VDEC+ RP G C++LP + CHC DG+ AG
Sbjct: 297 SFRHAAG-FLCHCPPGFE-GADCGVEVDECA-SRPCLNGGHCQDLPNGFQCHCPDGY-AG 352
Query: 226 PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHP 284
P + DV+EC + G C +TV + C C T GR+C + C P
Sbjct: 353 PTCE-EDVDECLSDPCL-HGGTCSDTVAGYICRCPE----TWGGRDCSVQLTGCQGHTCP 406
Query: 285 CGRDGNPSCTNTNGGYECSCGAG 307
P + Y C C G
Sbjct: 407 LAATCIPIFESGVHSYVCHCPPG 429
Score = 92.3 bits (219), Expect = 7e-18
Identities = 99/323 (30%), Positives = 130/323 (40%), Gaps = 69/323 (21%)
Query: 361 RKELCYDEWEAGRCHRARPLQ-LA-RPECCCSEGAAWGRYCE----RCP-AP-------- 405
R EL DE + CH + LA R EC C G A G CE C AP
Sbjct: 104 RCELDIDECASRPCHHGATCRNLADRYECHCPLGYA-GVTCEMEVDECASAPCLHGGSCL 162
Query: 406 -DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPD-GYVLAPD 462
F +C G G DLDEC+ +P C GG C + FRC+C GY +
Sbjct: 163 DGVGSFRCVCAPGYGGTRCQLDLDECQSQP--CAHGGTCHDLVNGFRCDCAGTGY----E 216
Query: 463 GLSCV-DADECALDPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRAS 519
G C + ECA P C N +C G + C C PG++ + C VD DECA
Sbjct: 217 GTHCEREVLECASAP--CEHNASCLEGLGSFRCLCWPGYS---GELCEVDEDECASSPCQ 271
Query: 520 CTFRC---------------------HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEP 558
RC A F C CP G+ A GV ++DEC P
Sbjct: 272 HGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGV---EVDECASRP 328
Query: 559 RVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSF 618
+ C+++ + C CP+GY + ED++EC L GG C +T +
Sbjct: 329 CLNGGHCQDLPNGFQCHCPDGYAGPTCE-------EDVDECLSDPCL-HGGTCSDTVAGY 380
Query: 619 LCDCDAGFEPSEDGTDCIDRRTG 641
+C C + G DC + TG
Sbjct: 381 ICRCPETW----GGRDCSVQLTG 399
Score = 74.9 bits (176), Expect = 1e-12
Identities = 67/206 (32%), Positives = 86/206 (41%), Gaps = 49/206 (23%)
Query: 472 CALDPRICGNGT-CSNTR-GGYEC-----------QCSPG---FTQGPDQT-----CV-- 508
CA DP C GT C T GGY C C G QGPD T CV
Sbjct: 42 CASDP--CAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPG 99
Query: 509 --------DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPR 559
D+DECA C N A + C CP GYA GV C ++DEC P
Sbjct: 100 FQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVTCEMEVDECASAPC 155
Query: 560 VCPHACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSF 618
+ +C + VGS+ C C GY T C+ D++EC+ Q GG C + F
Sbjct: 156 LHGGSCLDGVGSFRCVCAPGYGGT--------RCQLDLDECQSQ-PCAHGGTCHDLVNGF 206
Query: 619 LCDC-DAGFEPSEDGTDCIDRRTGTC 643
CDC G+E + + ++ + C
Sbjct: 207 RCDCAGTGYEGTHCEREVLECASAPC 232
Score = 68.5 bits (160), Expect = 9e-11
Identities = 47/121 (38%), Positives = 57/121 (47%), Gaps = 17/121 (14%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+VDECA+ P G C G FRCVC PGY G C D+DEC +P CH+
Sbjct: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGY--GGTRCQLDLDECQSQPCAHGGTCHDLV 203
Query: 800 GSYDCLCR-TGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA 857
+ C C TGYE G +C R+V EC C GS+ C C GY G+
Sbjct: 204 NGFRCDCAGTGYE----GTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYS--GEL 257
Query: 858 C 858
C
Sbjct: 258 C 258
Score = 62.5 bits (145), Expect = 6e-09
Identities = 36/94 (38%), Positives = 43/94 (45%), Gaps = 8/94 (8%)
Query: 760 PGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
P FRC C PG++ G C D+DECA RP C N Y+C C GY G
Sbjct: 89 PTGFRCYCVPGFQ--GPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVT 142
Query: 819 CR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C +VDEC C + GS+ C C GY
Sbjct: 143 CEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGY 176
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/107 (34%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 752 AAIPGLCA---PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRT 808
AA PG + F C C PG+ A + +VDECA RP C + + C C
Sbjct: 290 AAFPGAFSFRHAAGFLCHCPPGFEGA-DCGVEVDECASRPCLNGGHCQDLPNGFQCHCPD 348
Query: 809 GYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
GY G C DVDEC D CS+T Y C C + + R
Sbjct: 349 GYA----GPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGR 391
Score = 43.2 bits (97), Expect = 0.004
Identities = 31/88 (35%), Positives = 40/88 (45%), Gaps = 11/88 (12%)
Query: 464 LSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF- 522
L C A CA P + +G C + + C C PG+ +GP + VD C A C
Sbjct: 1052 LGCRGAPVCAPSPCL-HDGACRDLFDAFACACGPGW-EGP-RCEAHVDPCHS--APCARG 1106
Query: 523 RCH-NTAGSFRCTCPYGYAVAADGVHCR 549
RCH + G F C CP G+ G CR
Sbjct: 1107 RCHTHPDGRFECRCPPGFG----GPRCR 1130
Score = 42.7 bits (96), Expect = 0.005
Identities = 37/95 (38%), Positives = 44/95 (46%), Gaps = 15/95 (15%)
Query: 747 DVDECAAIP----GLCAP--GRFRCVC-GPGYRPAGEVCA-DVDECAVRPPPCDQLCHNT 798
D+DEC + P G C FRC C G GY G C +V ECA P + C
Sbjct: 184 DLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYE--GTHCEREVLECASAPCEHNASCLEG 241
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ 833
GS+ CLC GY G C +VDE E + CQ
Sbjct: 242 LGSFRCLCWPGY----SGELC-EVDEDECASSPCQ 271
Score = 42.7 bits (96), Expect = 0.005
Identities = 25/62 (40%), Positives = 28/62 (45%), Gaps = 7/62 (11%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLP-GAFECRCPP 139
G C D F C C G+E VD C P RG +C P G FECRCPP
Sbjct: 1069 GACRDLFDAFACACGPGWEGPRCE---AHVDPCH-SAPCARG--RCHTHPDGRFECRCPP 1122
Query: 140 GY 141
G+
Sbjct: 1123 GF 1124
Score = 40.3 bits (90), Expect = 0.028
Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 11/72 (15%)
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECS 303
+G CR+ +F C C PG+ +G C VD C P GR T+ +G +EC
Sbjct: 1068 DGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAPCARGR----CHTHPDGRFECR 1119
Query: 304 CGAGWKLVGRRC 315
C G+ G RC
Sbjct: 1120 CPPGFG--GPRC 1129
Score = 39.9 bits (89), Expect = 0.038
Identities = 28/90 (31%), Positives = 35/90 (38%), Gaps = 7/90 (7%)
Query: 416 GGMGRPNLTQD-LDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
GG NLT + E PD C GG C+ T F C CP + G +C C
Sbjct: 794 GGRQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT----GPTCAQQLWCP 849
Query: 474 LDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
P + TC G+ C F +GP
Sbjct: 850 GQPCL-PPATCEEVPDGFVCVAEATFREGP 878
Score = 39.1 bits (87), Expect = 0.066
Identities = 25/79 (31%), Positives = 30/79 (37%), Gaps = 7/79 (8%)
Query: 150 CEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDEC-SRPRPVCRNGTCE 208
C C G CR+ ++ C C PG+ VD C S P C G C
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWE-GPRCEAHVDPCHSAP---CARGRCH 1109
Query: 209 NLP-GAYLCHCDDGFKAGP 226
P G + C C GF GP
Sbjct: 1110 THPDGRFECRCPPGF-GGP 1127
Score = 39.1 bits (87), Expect = 0.066
Identities = 27/78 (34%), Positives = 33/78 (42%), Gaps = 9/78 (11%)
Query: 107 CRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG 165
CR C+ PC C +L AF C C PG+ P CE VD C C G
Sbjct: 1054 CRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE-GP---RCEAHVDPC-HSAPCARG 1106
Query: 166 DCR-NTIGSYRCECKPGY 182
C + G + C C PG+
Sbjct: 1107 RCHTHPDGRFECRCPPGF 1124
Score = 37.9 bits (84), Expect = 0.15
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 9/69 (13%)
Query: 434 PDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTC-SNTRGG 490
P C+ G C + +F C C G+ +G C D C P C G C ++ G
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAP--CARGRCHTHPDGR 1115
Query: 491 YECQCSPGF 499
+EC+C PGF
Sbjct: 1116 FECRCPPGF 1124
Score = 37.1 bits (82), Expect = 0.27
Identities = 18/49 (36%), Positives = 21/49 (42%), Gaps = 3/49 (6%)
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRC-VNTDGSFRCECPDGY 457
F C G P +D C P C GRC + DG F C CP G+
Sbjct: 1078 FACACGPGWEGPRCEAHVDPCHSAP--CARGRCHTHPDGRFECRCPPGF 1124
Score = 36.7 bits (81), Expect = 0.35
Identities = 20/77 (25%), Positives = 29/77 (37%), Gaps = 3/77 (3%)
Query: 150 CEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCEN 209
C D C + G C T + C C +T C C +P TCE
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT--GPTCAQQLWCPG-QPCLPPATCEE 861
Query: 210 LPGAYLCHCDDGFKAGP 226
+P ++C + F+ GP
Sbjct: 862 VPDGFVCVAEATFREGP 878
Score = 36.7 bits (81), Expect = 0.35
Identities = 21/75 (28%), Positives = 28/75 (37%), Gaps = 4/75 (5%)
Query: 507 CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
CV D C+ C T F CTCP + G C C +P + P CE
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT----GPTCAQQLWCPGQPCLPPATCE 860
Query: 567 NVVGSYICKCPEGYR 581
V ++C +R
Sbjct: 861 EVPDGFVCVAEATFR 875
Score = 36.7 bits (81), Expect = 0.35
Identities = 27/100 (27%), Positives = 37/100 (37%), Gaps = 9/100 (9%)
Query: 755 PGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYEL 812
PG R PG C CA P PC D C + ++ C C G+E
Sbjct: 1031 PGAAPGAREHFASWPGTPAPILGCRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE- 1087
Query: 813 DEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C VD C + ++ +G +EC C G+
Sbjct: 1088 ---GPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124
Score = 34.3 bits (75), Expect = 1.9
Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 12/81 (14%)
Query: 548 CRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLC 606
CR C P + AC ++ ++ C C G+ P+ CE ++ C C
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGW---EGPR-----CEAHVDPCHSAP--C 1103
Query: 607 SGGVC-INTDGSFLCDCDAGF 626
+ G C + DG F C C GF
Sbjct: 1104 ARGRCHTHPDGRFECRCPPGF 1124
>AF193055-1|AAG22483.1| 474|Homo sapiens unknown protein.
Length = 474
Score = 128 bits (308), Expect = 1e-28
Identities = 66/170 (38%), Positives = 97/170 (57%), Gaps = 13/170 (7%)
Query: 420 RPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRIC 479
R +QD++EC ++P C RCVNT GS++C C G++L PD +CV++ CA+ I
Sbjct: 9 RETCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA-TCVNSRTCAM---IN 63
Query: 480 GNGTCSNTRGGYECQC-SPGFTQGPD-QTCVDVDECAEGRASCTF--RCHNTAGSFRCTC 535
+C +T G +C C S G P+ + C+D+DECA G+ C + RC NT GS+ C C
Sbjct: 64 CQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKC 123
Query: 536 PYGYAV--AADGVHCRDIDECVQEPRVCPH--ACENVVGSYICKCPEGYR 581
G+ + + C DI+EC + C H C N GS+ CKC +GY+
Sbjct: 124 HIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYK 173
Score = 122 bits (294), Expect = 5e-27
Identities = 64/164 (39%), Positives = 80/164 (48%), Gaps = 9/164 (5%)
Query: 468 DADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNT 527
D +EC + PR C + C NT G Y+C C G PD TCV+ CA +C + C +T
Sbjct: 15 DVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDATCVNSRTCA--MINCQYSCEDT 71
Query: 528 AGSFRCTCP-YGYAVAADGVHCRDIDECVQEPRVCPH--ACENVVGSYICKCPEGYRRTS 584
+C CP G +A +G C DIDEC +CP+ C N GSY CKC G+
Sbjct: 72 EEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQY 131
Query: 585 APQDSENACEDINECEEQEDLCSGGV-CINTDGSFLCDCDAGFE 627
C DINEC CS C NT GSF C C G++
Sbjct: 132 I--SGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYK 173
Score = 113 bits (272), Expect = 3e-24
Identities = 66/172 (38%), Positives = 92/172 (53%), Gaps = 13/172 (7%)
Query: 151 EDVDECGDQ-RICDHGDCRNTIGSYRCECKPGYTLRENV-CRDVDECSRPRPVCRNGTCE 208
+DV+ECG + R C H C NT GSY+C C G+ L + C + C+ C+ +CE
Sbjct: 14 QDVNECGMKPRPCQHR-CVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMIN--CQY-SCE 69
Query: 209 NLPGAYLCHC-DDGFKAGPNN-DCVDVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTL 265
+ C C G + PN DC+D++EC G ++C N RC NT GS+ C+C G+ L
Sbjct: 70 DTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFEL 129
Query: 266 T-ADGR-NCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
GR +C D++EC H C N C NT G ++C C G+K G RC
Sbjct: 130 QYISGRYDCIDINECTMDSHTCSHHAN--CFNTQGSFKCKCKQGYKGNGLRC 179
Score = 99.1 bits (236), Expect = 6e-20
Identities = 60/178 (33%), Positives = 85/178 (47%), Gaps = 15/178 (8%)
Query: 108 RDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDC 167
+DV+EC PC+ +CVN G+++C C G+ L P C + C C + C
Sbjct: 14 QDVNECGMKPRPCQH--RCVNTHGSYKCFCLSGHMLMPDA-TCVNSRTCA-MINCQY-SC 68
Query: 168 RNTIGSYRCEC-KPGYTLREN--VCRDVDECSRPRPVC-RNGTCENLPGAYLCHCDDGFK 223
+T +C C G L N C D+DEC+ + +C N C N G+Y C C GF+
Sbjct: 69 EDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFE 128
Query: 224 ---AGPNNDCVDVNECREGGMVC-RNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE 277
DC+D+NEC C + C NT GSF+C+C GY +G C + E
Sbjct: 129 LQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY--KGNGLRCSAIPE 184
Score = 95.1 bits (226), Expect = 9e-19
Identities = 59/172 (34%), Positives = 84/172 (48%), Gaps = 14/172 (8%)
Query: 185 RENVCRDVDECS-RPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC 243
RE +DV+EC +PRP C++ C N G+Y C C G P+ CV+ C M+
Sbjct: 9 RETCSQDVNECGMKPRP-CQH-RCVNTHGSYKCFCLSGHMLMPDATCVNSRTC---AMIN 63
Query: 244 RNGRCRNTVGSFRCEC-APGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYEC 302
C +T +C C + G L +GR+C D+DEC C N C NT G Y C
Sbjct: 64 CQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPY--NRRCVNTFGSYYC 121
Query: 303 SCGAGWKLV---GRR-CVDRDECKELPYVCAG-GECRNFNGGYVCECPAGWR 349
C G++L GR C+D +EC + C+ C N G + C+C G++
Sbjct: 122 KCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYK 173
Score = 84.6 bits (200), Expect = 1e-15
Identities = 43/104 (41%), Positives = 58/104 (55%), Gaps = 9/104 (8%)
Query: 764 RCVC-GPGYR--PAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGA- 817
+C+C G R P G C D+DECA C ++ C NT GSY C C G+EL
Sbjct: 76 QCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGR 135
Query: 818 -NCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDAC 858
+C D++EC D+HTC C NT+GS++C C+ GY+ G C
Sbjct: 136 YDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRC 179
Score = 81.4 bits (192), Expect = 1e-14
Identities = 47/141 (33%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Query: 82 TCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPG 140
+C DT G QC C G C D+DEC+ G+ C +CVN G++ C+C G
Sbjct: 67 SCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIG 126
Query: 141 YRL--TPSLDECEDVDECG-DQRICD-HGDCRNTIGSYRCECKPGYTLRENVCRDVDECS 196
+ L +C D++EC D C H +C NT GS++C+CK GY C + E S
Sbjct: 127 FELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENS 186
Query: 197 RPRPVCRNGTCENLPGAYLCH 217
+ GT ++ L H
Sbjct: 187 VKEVLRAPGTIKDRIKKLLAH 207
Score = 76.6 bits (180), Expect = 4e-13
Identities = 48/137 (35%), Positives = 64/137 (46%), Gaps = 10/137 (7%)
Query: 505 QTCV-DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH 563
+TC DV+EC C RC NT GS++C C G+ + D C + C C +
Sbjct: 10 ETCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDAT-CVNSRTCAMIN--CQY 66
Query: 564 ACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCS-GGVCINTDGSFLCDC 622
+CE+ C CP R AP + C DI+EC + +C C+NT GS+ C C
Sbjct: 67 SCEDTEEGPQCLCPSSGLRL-APNGRD--CLDIDECASGKVICPYNRRCVNTFGSYYCKC 123
Query: 623 DAGFEPS--EDGTDCID 637
GFE DCID
Sbjct: 124 HIGFELQYISGRYDCID 140
Score = 61.3 bits (142), Expect = 1e-08
Identities = 30/73 (41%), Positives = 39/73 (53%), Gaps = 4/73 (5%)
Query: 776 EVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ 834
E C+ DV+EC ++P PC C NT GSY C C +G+ L D A C + C CQ
Sbjct: 10 ETCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPD-ATCVNSRTCA--MINCQY 66
Query: 835 ICSNTEGSYECSC 847
C +TE +C C
Sbjct: 67 SCEDTEEGPQCLC 79
Score = 52.0 bits (119), Expect = 9e-06
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 55 GEYINPVTNETKPIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTS--HLCRDVD 111
G + P + IDEC +C C +T + C C G+E S + C D++
Sbjct: 83 GLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDIN 142
Query: 112 ECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
EC+ C A C N G+F+C+C GY+
Sbjct: 143 ECTMDSHTCSHHANCFNTQGSFKCKCKQGYK 173
Score = 43.2 bits (97), Expect = 0.004
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 16/92 (17%)
Query: 747 DVDECAAIPGLCAPGR--------FRCVCGPGYRP---AGEV-CADVDECAVRPPPCDQ- 793
D+DECA+ +C R + C C G+ +G C D++EC + C
Sbjct: 95 DIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHH 154
Query: 794 -LCHNTDGSYDCLCRTGYELDEDGANCRDVDE 824
C NT GS+ C C+ GY+ +G C + E
Sbjct: 155 ANCFNTQGSFKCKCKQGYK--GNGLRCSAIPE 184
Score = 41.5 bits (93), Expect = 0.012
Identities = 19/41 (46%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 859
+DV+EC CQ C NT GSY+C C G+ DA CV
Sbjct: 14 QDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDATCV 54
>AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein.
Length = 1176
Score = 126 bits (305), Expect = 3e-28
Identities = 118/378 (31%), Positives = 156/378 (41%), Gaps = 46/378 (12%)
Query: 211 PGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR-CRNTVGSFRCECAPGYTLTADG 269
P + C+C GF+ GP + +D++EC C +G CRN + C C GY G
Sbjct: 89 PNGFRCYCVPGFQ-GPRCE-LDIDEC--ASRPCHHGATCRNLADRYECHCPLGYA----G 140
Query: 270 RNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYV 327
C +VDEC P G SC + G + C C G+ G RC +D DEC+ P
Sbjct: 141 VTCETEVDECASAPCLHGA----SCLDGVGSFRCVCAPGYG--GTRCQLDLDECQSQP-- 192
Query: 328 CA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC-HRARPLQ-LAR 384
CA GG C + G+ C+C AG ++ T ER+ L E + C H A L+ L
Sbjct: 193 CAHGGTCHDLVNGFRCDC-AGTGYEGTHC----EREVL---ECASAPCEHNASCLEGLGS 244
Query: 385 PECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN 444
C C G + G CE + CQ G GR D G
Sbjct: 245 FRCLCWPGYS-GELCE---VDEDECASSPCQHG-GRCLQRSDPALYGGVQAAFPGAFSFR 299
Query: 445 TDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
F C CP G+ +G C V+ DECA P + G G C + G++C C G+ GP
Sbjct: 300 HAAGFLCHCPPGF----EGADCGVEVDECASRPCLNG-GHCQDLPNGFQCHCPDGYA-GP 353
Query: 504 DQTCV-DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDID-ECVQEPRVC 561
TC DVDEC C +T + C CP + V C
Sbjct: 354 --TCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATC 411
Query: 562 PHACENVVGSYICKCPEG 579
E+ V SY+C CP G
Sbjct: 412 IPIFESGVHSYVCHCPPG 429
Score = 126 bits (304), Expect = 3e-28
Identities = 96/284 (33%), Positives = 129/284 (45%), Gaps = 44/284 (15%)
Query: 87 PTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPS 146
P GF+C C G++ D+DEC+ PC A C NL +EC CP GY
Sbjct: 89 PNGFRCYCVPGFQGPRCE---LDIDECA--SRPCHHGATCRNLADRYECHCPLGYAGVT- 142
Query: 147 LDECE-DVDECGDQRICDHG-DCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCR 203
CE +VDEC C HG C + +GS+RC C PGY C+ D+DEC + +P
Sbjct: 143 ---CETEVDECASAP-CLHGASCLDGVGSFRCVCAPGY--GGTRCQLDLDEC-QSQPCAH 195
Query: 204 NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGY 263
GTC +L + C C G + + +V EC N C +GSFRC C PGY
Sbjct: 196 GGTCHDLVNGFRCDCAGTGYEGTHCE-REVLECASAPCE-HNASCLEGLGSFRCLCWPGY 253
Query: 264 TLTADGRNCR-DVDECDELP--H--PCGRDGNPS-------------CTNTNGGYECSCG 305
+ G C D DEC P H C + +P+ G+ C C
Sbjct: 254 S----GELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCP 309
Query: 306 AGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYVCECPAGW 348
G++ G C V+ DEC P + GG C++ G+ C CP G+
Sbjct: 310 PGFE--GADCGVEVDECASRPCL-NGGHCQDLPNGFQCHCPDGY 350
Score = 115 bits (276), Expect = 8e-25
Identities = 86/287 (29%), Positives = 121/287 (42%), Gaps = 36/287 (12%)
Query: 385 PECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCV 443
P C ++ G C PD F C G P D+DEC RP C G C
Sbjct: 68 PRGCATQPCHHGALCVP-QGPDPNGFRCYCVPGFQGPRCELDIDECASRP--CHHGATCR 124
Query: 444 NTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG 502
N + C CP GY G++C + DECA P + G +C + G + C C+PG+ G
Sbjct: 125 NLADRYECHCPLGYA----GVTCETEVDECASAPCLHG-ASCLDGVGSFRCVCAPGY--G 177
Query: 503 PDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVC 561
+ +D+DEC + CH+ FRC C +G HC R++ EC P C
Sbjct: 178 GTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA---GTGYEGTHCEREVLECASAP--C 232
Query: 562 PH--ACENVVGSYICKCPEGYRRTSAPQDSENA----CEDINECEEQED-LCSGGVCINT 614
H +C +GS+ C C GY D + C+ C ++ D GGV
Sbjct: 233 EHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAF 292
Query: 615 DGSF--------LCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCE 653
G+F LC C GFE ++ G + + + C L G C+
Sbjct: 293 PGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPC---LNGGHCQ 336
Score = 111 bits (267), Expect = 1e-23
Identities = 103/323 (31%), Positives = 136/323 (42%), Gaps = 57/323 (17%)
Query: 20 KYLCCCSVGHAWGAPCEACPPRGSPA---HTALCGEKPGEY---INPVTNETK---PIDE 70
+Y C C +G+A G CE + A H A C + G + P T+ +DE
Sbjct: 129 RYECHCPLGYA-GVTCETEVDECASAPCLHGASCLDGVGSFRCVCAPGYGGTRCQLDLDE 187
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGC-DHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
C P GTCHD GF+C C GYE +H R+V EC+ PC A C+
Sbjct: 188 CQSQP-CAHGGTCHDLVNGFRCDCAGTGYE---GTHCEREVLECA--SAPCEHNASCLEG 241
Query: 130 PGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGD-C-------------------- 167
G+F C C PGY S + CE D DEC C HG C
Sbjct: 242 LGSFRCLCWPGY----SGELCEVDEDECASSP-CQHGGRCLQRSDPALYGGVQAAFPGAF 296
Query: 168 --RNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAG 225
R+ G + C C PG+ + +VDEC+ RP G C++LP + CHC DG+ AG
Sbjct: 297 SFRHAAG-FLCHCPPGFE-GADCGVEVDECA-SRPCLNGGHCQDLPNGFQCHCPDGY-AG 352
Query: 226 PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHP 284
P + DV+EC + G C +TV + C C T GR+C + C P
Sbjct: 353 PTCE-EDVDECLSDPCL-HGGTCSDTVAGYICRCPE----TWGGRDCSVQLTGCQGHTCP 406
Query: 285 CGRDGNPSCTNTNGGYECSCGAG 307
P + Y C C G
Sbjct: 407 LAATCIPIFESGVHSYVCHCPPG 429
Score = 92.3 bits (219), Expect = 7e-18
Identities = 99/323 (30%), Positives = 130/323 (40%), Gaps = 69/323 (21%)
Query: 361 RKELCYDEWEAGRCHRARPLQ-LA-RPECCCSEGAAWGRYCE----RCP-AP-------- 405
R EL DE + CH + LA R EC C G A G CE C AP
Sbjct: 104 RCELDIDECASRPCHHGATCRNLADRYECHCPLGYA-GVTCETEVDECASAPCLHGASCL 162
Query: 406 -DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPD-GYVLAPD 462
F +C G G DLDEC+ +P C GG C + FRC+C GY +
Sbjct: 163 DGVGSFRCVCAPGYGGTRCQLDLDECQSQP--CAHGGTCHDLVNGFRCDCAGTGY----E 216
Query: 463 GLSCV-DADECALDPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRAS 519
G C + ECA P C N +C G + C C PG++ + C VD DECA
Sbjct: 217 GTHCEREVLECASAP--CEHNASCLEGLGSFRCLCWPGYS---GELCEVDEDECASSPCQ 271
Query: 520 CTFRC---------------------HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEP 558
RC A F C CP G+ A GV ++DEC P
Sbjct: 272 HGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGV---EVDECASRP 328
Query: 559 RVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSF 618
+ C+++ + C CP+GY + ED++EC L GG C +T +
Sbjct: 329 CLNGGHCQDLPNGFQCHCPDGYAGPTCE-------EDVDECLSDPCL-HGGTCSDTVAGY 380
Query: 619 LCDCDAGFEPSEDGTDCIDRRTG 641
+C C + G DC + TG
Sbjct: 381 ICRCPETW----GGRDCSVQLTG 399
Score = 72.9 bits (171), Expect = 4e-12
Identities = 66/206 (32%), Positives = 85/206 (41%), Gaps = 49/206 (23%)
Query: 472 CALDPRICGNGT-CSNTR-GGYEC-----------QCSPG---FTQGPDQT-----CV-- 508
CA DP C GT C T GGY C C G QGPD CV
Sbjct: 42 CASDP--CAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPNGFRCYCVPG 99
Query: 509 --------DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPR 559
D+DECA C N A + C CP GYA GV C ++DEC P
Sbjct: 100 FQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVTCETEVDECASAPC 155
Query: 560 VCPHACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSF 618
+ +C + VGS+ C C GY T C+ D++EC+ Q GG C + F
Sbjct: 156 LHGASCLDGVGSFRCVCAPGYGGT--------RCQLDLDECQSQ-PCAHGGTCHDLVNGF 206
Query: 619 LCDC-DAGFEPSEDGTDCIDRRTGTC 643
CDC G+E + + ++ + C
Sbjct: 207 RCDCAGTGYEGTHCEREVLECASAPC 232
Score = 67.3 bits (157), Expect = 2e-10
Identities = 47/121 (38%), Positives = 57/121 (47%), Gaps = 17/121 (14%)
Query: 747 DVDECAAIPGL----CAPG--RFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+VDECA+ P L C G FRCVC PGY G C D+DEC +P CH+
Sbjct: 146 EVDECASAPCLHGASCLDGVGSFRCVCAPGY--GGTRCQLDLDECQSQPCAHGGTCHDLV 203
Query: 800 GSYDCLCR-TGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA 857
+ C C TGYE G +C R+V EC C GS+ C C GY G+
Sbjct: 204 NGFRCDCAGTGYE----GTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYS--GEL 257
Query: 858 C 858
C
Sbjct: 258 C 258
Score = 63.7 bits (148), Expect = 3e-09
Identities = 36/94 (38%), Positives = 43/94 (45%), Gaps = 8/94 (8%)
Query: 760 PGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 818
P FRC C PG++ G C D+DECA RP C N Y+C C GY G
Sbjct: 89 PNGFRCYCVPGFQ--GPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVT 142
Query: 819 CR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
C +VDEC C + GS+ C C GY
Sbjct: 143 CETEVDECASAPCLHGASCLDGVGSFRCVCAPGY 176
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/107 (34%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 752 AAIPGLCA---PGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRT 808
AA PG + F C C PG+ A + +VDECA RP C + + C C
Sbjct: 290 AAFPGAFSFRHAAGFLCHCPPGFEGA-DCGVEVDECASRPCLNGGHCQDLPNGFQCHCPD 348
Query: 809 GYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
GY G C DVDEC D CS+T Y C C + + R
Sbjct: 349 GYA----GPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGR 391
Score = 43.2 bits (97), Expect = 0.004
Identities = 31/88 (35%), Positives = 40/88 (45%), Gaps = 11/88 (12%)
Query: 464 LSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTF- 522
L C A CA P + +G C + + C C PG+ +GP + VD C A C
Sbjct: 1052 LGCRGAPVCAPSPCL-HDGACRDLFDAFACACGPGW-EGP-RCEAHVDPCHS--APCARG 1106
Query: 523 RCH-NTAGSFRCTCPYGYAVAADGVHCR 549
RCH + G F C CP G+ G CR
Sbjct: 1107 RCHTHPDGRFECRCPPGFG----GPRCR 1130
Score = 42.7 bits (96), Expect = 0.005
Identities = 37/95 (38%), Positives = 44/95 (46%), Gaps = 15/95 (15%)
Query: 747 DVDECAAIP----GLCAP--GRFRCVC-GPGYRPAGEVCA-DVDECAVRPPPCDQLCHNT 798
D+DEC + P G C FRC C G GY G C +V ECA P + C
Sbjct: 184 DLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYE--GTHCEREVLECASAPCEHNASCLEG 241
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ 833
GS+ CLC GY G C +VDE E + CQ
Sbjct: 242 LGSFRCLCWPGY----SGELC-EVDEDECASSPCQ 271
Score = 42.7 bits (96), Expect = 0.005
Identities = 25/62 (40%), Positives = 28/62 (45%), Gaps = 7/62 (11%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLP-GAFECRCPP 139
G C D F C C G+E VD C P RG +C P G FECRCPP
Sbjct: 1069 GACRDLFDAFACACGPGWEGPRCE---AHVDPCH-SAPCARG--RCHTHPDGRFECRCPP 1122
Query: 140 GY 141
G+
Sbjct: 1123 GF 1124
Score = 40.3 bits (90), Expect = 0.028
Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 11/72 (15%)
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECS 303
+G CR+ +F C C PG+ +G C VD C P GR T+ +G +EC
Sbjct: 1068 DGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAPCARGR----CHTHPDGRFECR 1119
Query: 304 CGAGWKLVGRRC 315
C G+ G RC
Sbjct: 1120 CPPGFG--GPRC 1129
Score = 39.9 bits (89), Expect = 0.038
Identities = 28/90 (31%), Positives = 35/90 (38%), Gaps = 7/90 (7%)
Query: 416 GGMGRPNLTQD-LDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECA 473
GG NLT + E PD C GG C+ T F C CP + G +C C
Sbjct: 794 GGRQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT----GPTCAQQLWCP 849
Query: 474 LDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
P + TC G+ C F +GP
Sbjct: 850 GQPCL-PPATCEEVPDGFVCVAEATFREGP 878
Score = 39.1 bits (87), Expect = 0.066
Identities = 25/79 (31%), Positives = 30/79 (37%), Gaps = 7/79 (8%)
Query: 150 CEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDEC-SRPRPVCRNGTCE 208
C C G CR+ ++ C C PG+ VD C S P C G C
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWE-GPRCEAHVDPCHSAP---CARGRCH 1109
Query: 209 NLP-GAYLCHCDDGFKAGP 226
P G + C C GF GP
Sbjct: 1110 THPDGRFECRCPPGF-GGP 1127
Score = 39.1 bits (87), Expect = 0.066
Identities = 27/78 (34%), Positives = 33/78 (42%), Gaps = 9/78 (11%)
Query: 107 CRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG 165
CR C+ PC C +L AF C C PG+ P CE VD C C G
Sbjct: 1054 CRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE-GP---RCEAHVDPC-HSAPCARG 1106
Query: 166 DCR-NTIGSYRCECKPGY 182
C + G + C C PG+
Sbjct: 1107 RCHTHPDGRFECRCPPGF 1124
Score = 37.9 bits (84), Expect = 0.15
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 9/69 (13%)
Query: 434 PDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGTC-SNTRGG 490
P C+ G C + +F C C G+ +G C D C P C G C ++ G
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAP--CARGRCHTHPDGR 1115
Query: 491 YECQCSPGF 499
+EC+C PGF
Sbjct: 1116 FECRCPPGF 1124
Score = 37.1 bits (82), Expect = 0.27
Identities = 18/49 (36%), Positives = 21/49 (42%), Gaps = 3/49 (6%)
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRC-VNTDGSFRCECPDGY 457
F C G P +D C P C GRC + DG F C CP G+
Sbjct: 1078 FACACGPGWEGPRCEAHVDPCHSAP--CARGRCHTHPDGRFECRCPPGF 1124
Score = 36.7 bits (81), Expect = 0.35
Identities = 20/77 (25%), Positives = 29/77 (37%), Gaps = 3/77 (3%)
Query: 150 CEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCEN 209
C D C + G C T + C C +T C C +P TCE
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT--GPTCAQQLWCPG-QPCLPPATCEE 861
Query: 210 LPGAYLCHCDDGFKAGP 226
+P ++C + F+ GP
Sbjct: 862 VPDGFVCVAEATFREGP 878
Score = 36.7 bits (81), Expect = 0.35
Identities = 21/75 (28%), Positives = 28/75 (37%), Gaps = 4/75 (5%)
Query: 507 CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACE 566
CV D C+ C T F CTCP + G C C +P + P CE
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT----GPTCAQQLWCPGQPCLPPATCE 860
Query: 567 NVVGSYICKCPEGYR 581
V ++C +R
Sbjct: 861 EVPDGFVCVAEATFR 875
Score = 36.7 bits (81), Expect = 0.35
Identities = 27/100 (27%), Positives = 37/100 (37%), Gaps = 9/100 (9%)
Query: 755 PGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYEL 812
PG R PG C CA P PC D C + ++ C C G+E
Sbjct: 1031 PGAAPGAREHFASWPGTPAPILGCRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE- 1087
Query: 813 DEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C VD C + ++ +G +EC C G+
Sbjct: 1088 ---GPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124
Score = 34.3 bits (75), Expect = 1.9
Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 12/81 (14%)
Query: 548 CRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLC 606
CR C P + AC ++ ++ C C G+ P+ CE ++ C C
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGW---EGPR-----CEAHVDPCHSAP--C 1103
Query: 607 SGGVC-INTDGSFLCDCDAGF 626
+ G C + DG F C C GF
Sbjct: 1104 ARGRCHTHPDGRFECRCPPGF 1124
>AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitamin
B12 receptor protein.
Length = 3494
Score = 126 bits (305), Expect = 3e-28
Identities = 116/364 (31%), Positives = 147/364 (40%), Gaps = 68/364 (18%)
Query: 283 HPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECK---ELPYVCA-GGECRNFN 337
+PC GN C N + + C C WK G C D +EC+ P C GG C N
Sbjct: 10 NPCQNGGN--CLNLHDSFFCICPPQWK--GPLCSADVNECEIYSGTPLSCQNGGTCVNTM 65
Query: 338 GGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGR 397
G Y C CP + C + YD+ E G R C G
Sbjct: 66 GSYSCHCPP----ETYGPQCASK-----YDDCEGGSVAR------------CVHGICEDL 104
Query: 398 YCERCPAPDSAEFMRICQGG-MGRPN---LTQDLDECRVRPDVCVG-GRCVNTDGSFRC- 451
E+ P ++ +C G M PN T D DEC +P C +C NT GSF C
Sbjct: 105 MREQAGEP---KYSCVCDAGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCG 161
Query: 452 ECPDGYVLAPDGLSCVDADECALDPRICGNGT---CSNTRGGYECQ-CSPGFTQGPDQTC 507
CP G+ +G C D +EC ++ C C NT G CQ C PG+ QG + C
Sbjct: 162 ACPTGW--QGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY-QGDGRVC 218
Query: 508 VDVDECAEGRASC--TFRCHNTAGSFR-CTCPYGYAVAADGVHCRDIDECVQEPRVC-PH 563
D C+ C C +T GS CTC GY G + CVQ +C H
Sbjct: 219 TLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPN-----GCVQLSNICLSH 273
Query: 564 ACEN-----VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSF 618
C N V Y CKC G+ N E+INEC L +GG C++ SF
Sbjct: 274 PCLNGQCIDTVSGYFCKCDSGWTGV-------NCTENINECLSNPCL-NGGTCVDGVDSF 325
Query: 619 LCDC 622
C+C
Sbjct: 326 SCEC 329
Score = 119 bits (286), Expect = 5e-26
Identities = 91/275 (33%), Positives = 127/275 (46%), Gaps = 31/275 (11%)
Query: 90 FQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFEC-RCPPGYRLTPSL 147
+ C CD G+ S C D DECS+ PC + QC N G+F C CP G++ +
Sbjct: 114 YSCVCDAGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYI 173
Query: 148 DECEDVDEC----GDQRICDHGDCRNTIGSYRCE-CKPGYTLRENVCRDVDECSRPRPVC 202
CED++EC G + +C NT GS C+ C PGY VC D CS C
Sbjct: 174 --CEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGC 231
Query: 203 R-NGTCENLPGAY-LCHCDDGFKA---GPNNDCVDV-NECREGGMVCRNGRCRNTVGSFR 256
+ +C + G+ LC C G+ GPN CV + N C C NG+C +TV +
Sbjct: 232 HPDASCSSTLGSLPLCTCLPGYTGNGYGPNG-CVQLSNICL--SHPCLNGQCIDTVSGYF 288
Query: 257 CECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
C+C G+T G NC +++EC L +PC G +C + + C C W G C
Sbjct: 289 CKCDSGWT----GVNCTENINEC--LSNPCLNGG--TCVDGVDSFSCECTRLW--TGALC 338
Query: 316 -VDRDECKE-LPYVCAGGECRNFNGGYVCECPAGW 348
V + C E L + R+ + GYV + W
Sbjct: 339 QVPQQVCGESLSGINGSFSYRSPDVGYVHDVNCFW 373
Score = 118 bits (283), Expect = 1e-25
Identities = 105/357 (29%), Positives = 150/357 (42%), Gaps = 62/357 (17%)
Query: 243 CRNG-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECD---ELPHPCGRDGNPSCTNTN 297
C+NG C N SF C C P + G C DV+EC+ P C G +C NT
Sbjct: 12 CQNGGNCLNLHDSFFCICPPQWK----GPLCSADVNECEIYSGTPLSCQNGG--TCVNTM 65
Query: 298 GGYECSCGAGWKLVGRRCVDR-DECKELPYV-CAGGECRNF---NGG---YVCECPAGWR 349
G Y C C + G +C + D+C+ C G C + G Y C C AGW
Sbjct: 66 GSYSCHCPP--ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWM 123
Query: 350 FDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAE 409
+ C +R E C ++ G C +C ++G+ YC CP
Sbjct: 124 SSPNSPACTLDRDE-C--SFQPGPCS-------TLVQCFNTQGSF---YCGACPT----- 165
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVGG---RCVNTDGSFRCE-CPDGYVLAPDGLS 465
G G + +D++EC + C CVNT GS C+ CP GY DG
Sbjct: 166 ------GWQGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QGDGRV 217
Query: 466 CVDADECALDPRIC-GNGTCSNTRGGYE-CQCSPGFT---QGPDQTCVDVDECAEGRASC 520
C D C++ C + +CS+T G C C PG+T GP+ CV +
Sbjct: 218 CTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPN-GCVQLSNICLSHPCL 276
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVCPHACENVVGSYICKC 576
+C +T + C C G+ GV+C +I+EC+ P + C + V S+ C+C
Sbjct: 277 NGQCIDTVSGYFCKCDSGWT----GVNCTENINECLSNPCLNGGTCVDGVDSFSCEC 329
Score = 113 bits (272), Expect = 3e-24
Identities = 110/380 (28%), Positives = 156/380 (41%), Gaps = 61/380 (16%)
Query: 152 DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECS--RPRPV-CRNG-T 206
D C + G+C N S+ C C P + + +C DV+EC P+ C+NG T
Sbjct: 3 DKKVCSSNPCQNGGNCLNLHDSFFCICPPQW--KGPLCSADVNECEIYSGTPLSCQNGGT 60
Query: 207 CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMV--CRNGRC----RNTVGS--FRCE 258
C N G+Y CHC GP C + EGG V C +G C R G + C
Sbjct: 61 CVNTMGSYSCHCPPE-TYGPQ--CASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCV 117
Query: 259 CAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYEC-SCGAGWKLVGRRCV 316
C G+ + + C D DEC P PC C NT G + C +C GW+ G C
Sbjct: 118 CDAGWMSSPNSPACTLDRDECSFQPGPCST--LVQCFNTQGSFYCGACPTGWQGNGYICE 175
Query: 317 DRDECKELPYVCAGG---ECRNFNGGYVCE-CPAGWRFDKTAAVCVDERKELCYDEWEAG 372
D +EC+ C+ EC N G C+ CP G++ D D +C G
Sbjct: 176 DINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTD----IC--SVSNG 229
Query: 373 RCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRV 432
CH P+ CS C P G G Q + C
Sbjct: 230 GCH---------PDASCSSTLGSLPLCTCLPGYTG--------NGYGPNGCVQLSNICLS 272
Query: 433 RPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD-ADECALDPRICGNGTCSNTRGGY 491
P C+ G+C++T + C+C G+ G++C + +EC +P + G GTC + +
Sbjct: 273 HP--CLNGQCIDTVSGYFCKCDSGWT----GVNCTENINECLSNPCLNG-GTCVDGVDSF 325
Query: 492 ECQCSPGFT----QGPDQTC 507
C+C+ +T Q P Q C
Sbjct: 326 SCECTRLWTGALCQVPQQVC 345
Score = 107 bits (257), Expect = 2e-22
Identities = 104/363 (28%), Positives = 149/363 (41%), Gaps = 54/363 (14%)
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR---LTPSLDECEDVDECGDQRICDH-G 165
VD+ PC+ C+NL +F C CPP ++ + ++ECE G C + G
Sbjct: 2 VDKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNECEIYS--GTPLSCQNGG 59
Query: 166 DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPV-CRNGTCENL------PGAYLCHC 218
C NT+GSY C C P T D+C C +G CE+L Y C C
Sbjct: 60 TCVNTMGSYSCHCPP-ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVC 118
Query: 219 DDGFKAGPNNDC--VDVNECR-EGGMVCRNGRCRNTVGSFRC-ECAPGYTLTADGRNCRD 274
D G+ + PN+ +D +EC + G +C NT GSF C C G+ +G C D
Sbjct: 119 DAGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGW--QGNGYICED 176
Query: 275 VDECDELPHPCGRDGNPSCTNTNGGYEC-SCGAGWKLVGRRCVDRDECKELPYVC-AGGE 332
++EC+ C C NT G C +C G++ GR C D C C
Sbjct: 177 INECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDAS 236
Query: 333 CRNFNGGY-VCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSE 391
C + G +C C G+ + + C + + L+ P C
Sbjct: 237 CSSTLGSLPLCTCLPGY----------------TGNGYGPNGCVQLSNICLSHP---CLN 277
Query: 392 GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFR 450
G +C S F + G G N T++++EC P C+ GG CV+ SF
Sbjct: 278 G--------QCIDTVSGYFCKCDSGWTG-VNCTENINECLSNP--CLNGGTCVDGVDSFS 326
Query: 451 CEC 453
CEC
Sbjct: 327 CEC 329
Score = 106 bits (254), Expect = 4e-22
Identities = 96/357 (26%), Positives = 136/357 (38%), Gaps = 49/357 (13%)
Query: 316 VDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC 374
VD+ C P C GG C N + + C CP W+ LC +
Sbjct: 2 VDKKVCSSNP--CQNGGNCLNLHDSFFCICPPQWK------------GPLCSADVNECEI 47
Query: 375 HRARPLQLARPECCCSEGAAWGRYCE-RCPAPDSAEFMRICQGGMGRPNLTQDLDECRVR 433
+ PL C + ++ +C P A C+GG + E +R
Sbjct: 48 YSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGG-SVARCVHGICEDLMR 106
Query: 434 PDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGT-CSNTRGGY 491
+ + C C G++ +P+ +C +D DEC+ P C C NT+G +
Sbjct: 107 EQA--------GEPKYSCVCDAGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSF 158
Query: 492 ECQCSPGFTQGPDQTCVDVDECAEGRASCT----FRCHNTAGSFRC-TCPYGYAVAADGV 546
C P QG C D++EC C+ C NT GS C CP GY DG
Sbjct: 159 YCGACPTGWQGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QGDGR 216
Query: 547 HCRDIDECVQEPRVC-PHA-CENVVGSY-ICKCPEGYRRTSAPQDSENACEDI-NECEEQ 602
C D C C P A C + +GS +C C GY N C + N C
Sbjct: 217 VCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGY---GPNGCVQLSNICLSH 273
Query: 603 EDLCSGGVCINTDGSFLCDCDAGF---EPSEDGTDCIDR---RTGTCYRSLVSGRCE 653
C G CI+T + C CD+G+ +E+ +C+ GTC + S CE
Sbjct: 274 P--CLNGQCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCE 328
Score = 101 bits (242), Expect = 1e-20
Identities = 82/237 (34%), Positives = 102/237 (43%), Gaps = 37/237 (15%)
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECAL---DPRICGN-GTCSNTRGGYECQ 494
GG C+N SF C CP + L D +EC + P C N GTC NT G Y C
Sbjct: 15 GGNCLNLHDSFFCICPPQW---KGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSCH 71
Query: 495 CSPGFTQGPDQTCVDVDECAEGRAS------CTFRCHNTAG--SFRCTCPYGYAVAADGV 546
C P T GP Q D+C G + C AG + C C G+ + +
Sbjct: 72 CPPE-TYGP-QCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWMSSPNSP 129
Query: 547 HCR-DIDECVQEPRVCPH--ACENVVGSYIC-KCPEGYRRTSAPQDSENACEDINECEEQ 602
C D DEC +P C C N GS+ C CP G+ Q + CEDINECE
Sbjct: 130 ACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGW------QGNGYICEDINECEIN 183
Query: 603 EDLCSGG---VCINTDGSFLCD-CDAGFEPSEDGTDCIDRRTGTCYRSLVSGRCEPE 655
CS C+NT GS C C G++ DG C T C S+ +G C P+
Sbjct: 184 NGGCSVAPPVECVNTPGSSHCQACPPGYQ--GDGRVC--TLTDIC--SVSNGGCHPD 234
Score = 58.4 bits (135), Expect = 1e-07
Identities = 43/126 (34%), Positives = 54/126 (42%), Gaps = 19/126 (15%)
Query: 747 DVDECAAIPGLCAP--------GRFRC-VCGPGYRPAGEVCADVDECAVRPPPCDQL--- 794
D DEC+ PG C+ G F C C G++ G +C D++EC + C
Sbjct: 134 DRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPV 193
Query: 795 -CHNTDGSYDC-LCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYE-CSCED 849
C NT GS C C GY+ DG C D C C CS+T GS C+C
Sbjct: 194 ECVNTPGSSHCQACPPGYQ--GDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLP 251
Query: 850 GYEKRG 855
GY G
Sbjct: 252 GYTGNG 257
Score = 50.0 bits (114), Expect = 4e-05
Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 9/99 (9%)
Query: 760 PGRFRC-VCGPGYRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYD-CLCRTGYELDED 815
PG C C PGY+ G VC D C+V C D C +T GS C C GY +
Sbjct: 199 PGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGY 258
Query: 816 GAN-CRDVDE-CERDTHTC-QQICSNTEGSYECSCEDGY 851
G N C + C +H C C +T Y C C+ G+
Sbjct: 259 GPNGCVQLSNICL--SHPCLNGQCIDTVSGYFCKCDSGW 295
Score = 39.9 bits (89), Expect = 0.038
Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 5/60 (8%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRC 137
C G C DT +G+ C CD G+ N + +++EC PC CV+ +F C C
Sbjct: 275 CLNGQCIDTVSGYFCKCDSGWTGVNCT---ENINECL--SNPCLNGGTCVDGVDSFSCEC 329
Score = 35.9 bits (79), Expect = 0.61
Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 12/75 (16%)
Query: 781 VDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHT---CQQ 834
VD+ PC C N S+ C+C ++ G C DV+ECE + T CQ
Sbjct: 2 VDKKVCSSNPCQNGGNCLNLHDSFFCICPPQWK----GPLCSADVNECEIYSGTPLSCQN 57
Query: 835 --ICSNTEGSYECSC 847
C NT GSY C C
Sbjct: 58 GGTCVNTMGSYSCHC 72
>AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12
receptor precursor protein.
Length = 3623
Score = 126 bits (305), Expect = 3e-28
Identities = 116/364 (31%), Positives = 147/364 (40%), Gaps = 68/364 (18%)
Query: 283 HPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECK---ELPYVCA-GGECRNFN 337
+PC GN C N + + C C WK G C D +EC+ P C GG C N
Sbjct: 139 NPCQNGGN--CLNLHDSFFCICPPQWK--GPLCSADVNECEIYSGTPLSCQNGGTCVNTM 194
Query: 338 GGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGR 397
G Y C CP + C + YD+ E G R C G
Sbjct: 195 GSYSCHCPP----ETYGPQCASK-----YDDCEGGSVAR------------CVHGICEDL 233
Query: 398 YCERCPAPDSAEFMRICQGG-MGRPN---LTQDLDECRVRPDVCVG-GRCVNTDGSFRC- 451
E+ P ++ +C G M PN T D DEC +P C +C NT GSF C
Sbjct: 234 MREQAGEP---KYSCVCDAGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCG 290
Query: 452 ECPDGYVLAPDGLSCVDADECALDPRICGNGT---CSNTRGGYECQ-CSPGFTQGPDQTC 507
CP G+ +G C D +EC ++ C C NT G CQ C PG+ QG + C
Sbjct: 291 ACPTGW--QGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY-QGDGRVC 347
Query: 508 VDVDECAEGRASC--TFRCHNTAGSFR-CTCPYGYAVAADGVHCRDIDECVQEPRVC-PH 563
D C+ C C +T GS CTC GY G + CVQ +C H
Sbjct: 348 TLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPN-----GCVQLSNICLSH 402
Query: 564 ACEN-----VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSF 618
C N V Y CKC G+ N E+INEC L +GG C++ SF
Sbjct: 403 PCLNGQCIDTVSGYFCKCDSGWTGV-------NCTENINECLSNPCL-NGGTCVDGVDSF 454
Query: 619 LCDC 622
C+C
Sbjct: 455 SCEC 458
Score = 119 bits (286), Expect = 5e-26
Identities = 91/275 (33%), Positives = 127/275 (46%), Gaps = 31/275 (11%)
Query: 90 FQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFEC-RCPPGYRLTPSL 147
+ C CD G+ S C D DECS+ PC + QC N G+F C CP G++ +
Sbjct: 243 YSCVCDAGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYI 302
Query: 148 DECEDVDEC----GDQRICDHGDCRNTIGSYRCE-CKPGYTLRENVCRDVDECSRPRPVC 202
CED++EC G + +C NT GS C+ C PGY VC D CS C
Sbjct: 303 --CEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGC 360
Query: 203 R-NGTCENLPGAY-LCHCDDGFKA---GPNNDCVDV-NECREGGMVCRNGRCRNTVGSFR 256
+ +C + G+ LC C G+ GPN CV + N C C NG+C +TV +
Sbjct: 361 HPDASCSSTLGSLPLCTCLPGYTGNGYGPNG-CVQLSNICL--SHPCLNGQCIDTVSGYF 417
Query: 257 CECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
C+C G+T G NC +++EC L +PC G +C + + C C W G C
Sbjct: 418 CKCDSGWT----GVNCTENINEC--LSNPCLNGG--TCVDGVDSFSCECTRLW--TGALC 467
Query: 316 -VDRDECKE-LPYVCAGGECRNFNGGYVCECPAGW 348
V + C E L + R+ + GYV + W
Sbjct: 468 QVPQQVCGESLSGINGSFSYRSPDVGYVHDVNCFW 502
Score = 118 bits (283), Expect = 1e-25
Identities = 105/357 (29%), Positives = 150/357 (42%), Gaps = 62/357 (17%)
Query: 243 CRNG-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECD---ELPHPCGRDGNPSCTNTN 297
C+NG C N SF C C P + G C DV+EC+ P C G +C NT
Sbjct: 141 CQNGGNCLNLHDSFFCICPPQWK----GPLCSADVNECEIYSGTPLSCQNGG--TCVNTM 194
Query: 298 GGYECSCGAGWKLVGRRCVDR-DECKELPYV-CAGGECRNF---NGG---YVCECPAGWR 349
G Y C C + G +C + D+C+ C G C + G Y C C AGW
Sbjct: 195 GSYSCHCPP--ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWM 252
Query: 350 FDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAE 409
+ C +R E C ++ G C +C ++G+ YC CP
Sbjct: 253 SSPNSPACTLDRDE-C--SFQPGPCS-------TLVQCFNTQGSF---YCGACPT----- 294
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVGG---RCVNTDGSFRCE-CPDGYVLAPDGLS 465
G G + +D++EC + C CVNT GS C+ CP GY DG
Sbjct: 295 ------GWQGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QGDGRV 346
Query: 466 CVDADECALDPRIC-GNGTCSNTRGGYE-CQCSPGFT---QGPDQTCVDVDECAEGRASC 520
C D C++ C + +CS+T G C C PG+T GP+ CV +
Sbjct: 347 CTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPN-GCVQLSNICLSHPCL 405
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVCPHACENVVGSYICKC 576
+C +T + C C G+ GV+C +I+EC+ P + C + V S+ C+C
Sbjct: 406 NGQCIDTVSGYFCKCDSGWT----GVNCTENINECLSNPCLNGGTCVDGVDSFSCEC 458
Score = 114 bits (275), Expect = 1e-24
Identities = 111/385 (28%), Positives = 158/385 (41%), Gaps = 61/385 (15%)
Query: 147 LDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECS--RPRPV-C 202
L + D C + G+C N S+ C C P + + +C DV+EC P+ C
Sbjct: 127 LQQTVDKKVCSSNPCQNGGNCLNLHDSFFCICPPQW--KGPLCSADVNECEIYSGTPLSC 184
Query: 203 RNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMV--CRNGRC----RNTVGS- 254
+NG TC N G+Y CHC GP C + EGG V C +G C R G
Sbjct: 185 QNGGTCVNTMGSYSCHCPPE-TYGPQ--CASKYDDCEGGSVARCVHGICEDLMREQAGEP 241
Query: 255 -FRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYEC-SCGAGWKLV 311
+ C C G+ + + C D DEC P PC C NT G + C +C GW+
Sbjct: 242 KYSCVCDAGWMSSPNSPACTLDRDECSFQPGPCST--LVQCFNTQGSFYCGACPTGWQGN 299
Query: 312 GRRCVDRDECKELPYVCAGG---ECRNFNGGYVCE-CPAGWRFDKTAAVCVDERKELCYD 367
G C D +EC+ C+ EC N G C+ CP G++ D D +C
Sbjct: 300 GYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTD----IC-- 353
Query: 368 EWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDL 427
G CH P+ CS C P G G Q
Sbjct: 354 SVSNGGCH---------PDASCSSTLGSLPLCTCLPGYTG--------NGYGPNGCVQLS 396
Query: 428 DECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD-ADECALDPRICGNGTCSN 486
+ C P C+ G+C++T + C+C G+ G++C + +EC +P + G GTC +
Sbjct: 397 NICLSHP--CLNGQCIDTVSGYFCKCDSGWT----GVNCTENINECLSNPCLNG-GTCVD 449
Query: 487 TRGGYECQCSPGFT----QGPDQTC 507
+ C+C+ +T Q P Q C
Sbjct: 450 GVDSFSCECTRLWTGALCQVPQQVC 474
Score = 107 bits (258), Expect = 1e-22
Identities = 105/367 (28%), Positives = 151/367 (41%), Gaps = 54/367 (14%)
Query: 106 LCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR---LTPSLDECEDVDECGDQRIC 162
L + VD+ PC+ C+NL +F C CPP ++ + ++ECE G C
Sbjct: 127 LQQTVDKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNECEIYS--GTPLSC 184
Query: 163 DH-GDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPV-CRNGTCENL------PGAY 214
+ G C NT+GSY C C P T D+C C +G CE+L Y
Sbjct: 185 QNGGTCVNTMGSYSCHCPP-ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKY 243
Query: 215 LCHCDDGFKAGPNNDC--VDVNECR-EGGMVCRNGRCRNTVGSFRC-ECAPGYTLTADGR 270
C CD G+ + PN+ +D +EC + G +C NT GSF C C G+ +G
Sbjct: 244 SCVCDAGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGW--QGNGY 301
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYEC-SCGAGWKLVGRRCVDRDECKELPYVC- 328
C D++EC+ C C NT G C +C G++ GR C D C C
Sbjct: 302 ICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCH 361
Query: 329 AGGECRNFNGGY-VCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPEC 387
C + G +C C G+ + + C + + L+ P
Sbjct: 362 PDASCSSTLGSLPLCTCLPGY----------------TGNGYGPNGCVQLSNICLSHP-- 403
Query: 388 CCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTD 446
C G +C S F + G G N T++++EC P C+ GG CV+
Sbjct: 404 -CLNG--------QCIDTVSGYFCKCDSGWTG-VNCTENINECLSNP--CLNGGTCVDGV 451
Query: 447 GSFRCEC 453
SF CEC
Sbjct: 452 DSFSCEC 458
Score = 106 bits (255), Expect = 3e-22
Identities = 96/360 (26%), Positives = 138/360 (38%), Gaps = 49/360 (13%)
Query: 313 RRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEA 371
++ VD+ C P C GG C N + + C CP W+ LC +
Sbjct: 128 QQTVDKKVCSSNP--CQNGGNCLNLHDSFFCICPPQWK------------GPLCSADVNE 173
Query: 372 GRCHRARPLQLARPECCCSEGAAWGRYCE-RCPAPDSAEFMRICQGGMGRPNLTQDLDEC 430
+ PL C + ++ +C P A C+GG + E
Sbjct: 174 CEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGG-SVARCVHGICED 232
Query: 431 RVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGT-CSNTR 488
+R + + C C G++ +P+ +C +D DEC+ P C C NT+
Sbjct: 233 LMREQA--------GEPKYSCVCDAGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQ 284
Query: 489 GGYECQCSPGFTQGPDQTCVDVDECAEGRASCT----FRCHNTAGSFRC-TCPYGYAVAA 543
G + C P QG C D++EC C+ C NT GS C CP GY
Sbjct: 285 GSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QG 342
Query: 544 DGVHCRDIDECVQEPRVC-PHA-CENVVGSY-ICKCPEGYRRTSAPQDSENACEDI-NEC 599
DG C D C C P A C + +GS +C C GY N C + N C
Sbjct: 343 DGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGY---GPNGCVQLSNIC 399
Query: 600 EEQEDLCSGGVCINTDGSFLCDCDAGF---EPSEDGTDCIDR---RTGTCYRSLVSGRCE 653
C G CI+T + C CD+G+ +E+ +C+ GTC + S CE
Sbjct: 400 LSHP--CLNGQCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCE 457
Score = 101 bits (243), Expect = 8e-21
Identities = 86/254 (33%), Positives = 109/254 (42%), Gaps = 38/254 (14%)
Query: 423 LTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECAL---DPRI 478
L Q +D+ + C GG C+N SF C CP + L D +EC + P
Sbjct: 127 LQQTVDKKVCSSNPCQNGGNCLNLHDSFFCICPPQW---KGPLCSADVNECEIYSGTPLS 183
Query: 479 CGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRAS------CTFRCHNTAG-- 529
C N GTC NT G Y C C P T GP Q D+C G + C AG
Sbjct: 184 CQNGGTCVNTMGSYSCHCPPE-TYGP-QCASKYDDCEGGSVARCVHGICEDLMREQAGEP 241
Query: 530 SFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPH--ACENVVGSYIC-KCPEGYRRTSA 585
+ C C G+ + + C D DEC +P C C N GS+ C CP G+
Sbjct: 242 KYSCVCDAGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGW----- 296
Query: 586 PQDSENACEDINECEEQEDLCSGG---VCINTDGSFLCD-CDAGFEPSEDGTDCIDRRTG 641
Q + CEDINECE CS C+NT GS C C G++ DG C T
Sbjct: 297 -QGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQ--GDGRVC--TLTD 351
Query: 642 TCYRSLVSGRCEPE 655
C S+ +G C P+
Sbjct: 352 IC--SVSNGGCHPD 363
Score = 58.4 bits (135), Expect = 1e-07
Identities = 43/126 (34%), Positives = 54/126 (42%), Gaps = 19/126 (15%)
Query: 747 DVDECAAIPGLCAP--------GRFRC-VCGPGYRPAGEVCADVDECAVRPPPCDQL--- 794
D DEC+ PG C+ G F C C G++ G +C D++EC + C
Sbjct: 263 DRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPV 322
Query: 795 -CHNTDGSYDC-LCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYE-CSCED 849
C NT GS C C GY+ DG C D C C CS+T GS C+C
Sbjct: 323 ECVNTPGSSHCQACPPGYQ--GDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLP 380
Query: 850 GYEKRG 855
GY G
Sbjct: 381 GYTGNG 386
Score = 50.0 bits (114), Expect = 4e-05
Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 9/99 (9%)
Query: 760 PGRFRC-VCGPGYRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYD-CLCRTGYELDED 815
PG C C PGY+ G VC D C+V C D C +T GS C C GY +
Sbjct: 328 PGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGY 387
Query: 816 GAN-CRDVDE-CERDTHTC-QQICSNTEGSYECSCEDGY 851
G N C + C +H C C +T Y C C+ G+
Sbjct: 388 GPNGCVQLSNICL--SHPCLNGQCIDTVSGYFCKCDSGW 424
Score = 39.9 bits (89), Expect = 0.038
Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 5/60 (8%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRC 137
C G C DT +G+ C CD G+ N + +++EC PC CV+ +F C C
Sbjct: 404 CLNGQCIDTVSGYFCKCDSGWTGVNCT---ENINECL--SNPCLNGGTCVDGVDSFSCEC 458
Score = 35.9 bits (79), Expect = 0.61
Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 12/75 (16%)
Query: 781 VDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHT---CQQ 834
VD+ PC C N S+ C+C ++ G C DV+ECE + T CQ
Sbjct: 131 VDKKVCSSNPCQNGGNCLNLHDSFFCICPPQWK----GPLCSADVNECEIYSGTPLSCQN 186
Query: 835 --ICSNTEGSYECSC 847
C NT GSY C C
Sbjct: 187 GGTCVNTMGSYSCHC 201
>Y00692-1|CAA68687.1| 676|Homo sapiens preproprotein S protein.
Length = 676
Score = 123 bits (297), Expect = 2e-27
Identities = 65/184 (35%), Positives = 104/184 (56%), Gaps = 18/184 (9%)
Query: 461 PDGLSCVDA--DECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEG- 516
PD SCV+A D+C+ P G +C + + + C C PG+ QG ++ D++EC +
Sbjct: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGW-QG-EKCEFDINECKDPS 165
Query: 517 --RASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYI 573
C+ C NT GS+ C+C G+ + ++ C+D+DEC +P +C A C+N+ G +
Sbjct: 166 NINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFE 225
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDA--GFEPSED 631
C+CPEGYR +CEDI+EC E++C+ +C+N G + C CD GF+ ++D
Sbjct: 226 CECPEGYRYNL----KSKSCEDIDEC--SENMCA-QLCVNYPGGYTCYCDGKKGFKLAQD 278
Query: 632 GTDC 635
C
Sbjct: 279 QKSC 282
Score = 109 bits (263), Expect = 3e-23
Identities = 62/179 (34%), Positives = 90/179 (50%), Gaps = 20/179 (11%)
Query: 111 DECSWGRPPCR--GMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG-- 165
D+CS PC G C + +F C C PG++ ++CE D++EC D + G
Sbjct: 119 DQCS--PLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCS 172
Query: 166 -DCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
C NT GSY C CK G+ + N C+DVDECS +C C+N+PG + C C +G+
Sbjct: 173 QICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
Query: 223 KAG-PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCEC--APGYTLTADGRNCRDVDEC 278
+ + C D++EC E +C C N G + C C G+ L D ++C V C
Sbjct: 233 RYNLKSKSCEDIDECSEN--MCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 109 bits (261), Expect = 5e-23
Identities = 63/177 (35%), Positives = 85/177 (48%), Gaps = 20/177 (11%)
Query: 145 PSLDECEDV--DECGDQRICDHG--DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRP 200
P L C + D+C + G C++ S+ C CKPG+ E D++EC P
Sbjct: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ-GEKCEFDINECKDPSN 166
Query: 201 VCRNG----TCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSF 255
+ NG C+N PG+Y C C +GF N DC DV+EC +C C+N G F
Sbjct: 167 I--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDF 224
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA--GWKL 310
CEC GY ++C D+DEC E + C + C N GGY C C G+KL
Sbjct: 225 ECECPEGYRYNLKSKSCEDIDECSE--NMCAQ----LCVNYPGGYTCYCDGKKGFKL 275
Score = 105 bits (252), Expect = 7e-22
Identities = 51/153 (33%), Positives = 75/153 (49%), Gaps = 7/153 (4%)
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR--CVNTDGSFRCECPDGYVLAPDGLS 465
A F C+ G D++EC+ ++ G C NT GS+ C C +G+V+ +
Sbjct: 139 ASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKD 198
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG-PDQTCVDVDECAEGRASCTFRC 524
C D DEC+L P ICG C N G +EC+C G+ ++C D+DEC+E C C
Sbjct: 199 CKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSEN--MCAQLC 256
Query: 525 HNTAGSFRCTC--PYGYAVAADGVHCRDIDECV 555
N G + C C G+ +A D C + C+
Sbjct: 257 VNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCL 289
Score = 99.5 bits (237), Expect = 4e-20
Identities = 60/170 (35%), Positives = 87/170 (51%), Gaps = 21/170 (12%)
Query: 184 LRENVCRDVDECSRPRPVCRNG--TCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGG 240
LR V D+CS P P +G +C++ ++ C C G++ C D+NEC++
Sbjct: 110 LRSCVNAIPDQCS-PLPCNEDGYMSCKDGKASFTCTCKPGWQG---EKCEFDINECKDPS 165
Query: 241 MVCRNGRCR----NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
+ NG C NT GS+ C C G+ + ++ ++C+DVDEC P CG C N
Sbjct: 166 NI--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG---TAVCKNI 220
Query: 297 NGGYECSCGAGWK--LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
G +EC C G++ L + C D DEC E +CA C N+ GGY C C
Sbjct: 221 PGDFECECPEGYRYNLKSKSCEDIDECSE--NMCA-QLCVNYPGGYTCYC 267
Score = 93.1 bits (221), Expect = 4e-18
Identities = 47/117 (40%), Positives = 61/117 (52%), Gaps = 7/117 (5%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
C +TP + C C +G+ + C+DVDECS +P G A C N+PG FEC CP GYR
Sbjct: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSL-KPSICGTAVCKNIPGDFECECPEGYR 233
Query: 143 LTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCEC--KPGYTLREN--VCRDVDEC 195
CED+DEC + +C C N G Y C C K G+ L ++ C V C
Sbjct: 234 YNLKSKSCEDIDEC-SENMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 87.0 bits (206), Expect = 3e-16
Identities = 45/128 (35%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Query: 236 CREGG-MVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSC 293
C E G M C++G+ SF C C PG+ G C D++EC + P + C
Sbjct: 126 CNEDGYMSCKDGKA-----SFTCTCKPGW----QGEKCEFDINECKD-PSNINGGCSQIC 175
Query: 294 TNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFD 351
NT G Y CSC G+ ++ + C D DEC P +C C+N G + CECP G+R++
Sbjct: 176 DNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYN 235
Query: 352 KTAAVCVD 359
+ C D
Sbjct: 236 LKSKSCED 243
Score = 83.4 bits (197), Expect = 3e-15
Identities = 44/118 (37%), Positives = 63/118 (53%), Gaps = 19/118 (16%)
Query: 749 DECAAIP----GL--CAPGR--FRCVCGPGYRPAGEVCA-DVDECAVRPPP-----CDQL 794
D+C+ +P G C G+ F C C PG++ GE C D++EC + P C Q+
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ--GEKCEFDINEC--KDPSNINGGCSQI 174
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGY 851
C NT GSY C C+ G+ + + +C+DVDEC C +C N G +EC C +GY
Sbjct: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
Score = 77.8 bits (183), Expect = 2e-13
Identities = 48/157 (30%), Positives = 66/157 (42%), Gaps = 24/157 (15%)
Query: 18 QTKYLCCCSVGHAW-GAPCE----AC--PPRGSPAHTALCGEKPGEYINPVTN------- 63
+ + C C G W G CE C P + + +C PG Y N
Sbjct: 138 KASFTCTCKPG--WQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSN 195
Query: 64 --ETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
+ K +DEC + P +C C + P F+C C GY ++ S C D+DECS C
Sbjct: 196 KKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS--ENMCA 253
Query: 122 GMAQCVNLPGAFECRC--PPGYRLTPSLDECEDVDEC 156
+ CVN PG + C C G++L CE V C
Sbjct: 254 QL--CVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 77.4 bits (182), Expect = 2e-13
Identities = 39/114 (34%), Positives = 57/114 (50%), Gaps = 14/114 (12%)
Query: 747 DVDEC---AAIPGLCA------PGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQ-L 794
D++EC + I G C+ PG + C C G+ C DVDEC+++P C +
Sbjct: 157 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAV 216
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCE 848
C N G ++C C GY + +C D+DEC + C Q+C N G Y C C+
Sbjct: 217 CKNIPGDFECECPEGYRYNLKSKSCEDIDECSE--NMCAQLCVNYPGGYTCYCD 268
Score = 75.8 bits (178), Expect = 6e-13
Identities = 39/118 (33%), Positives = 54/118 (45%), Gaps = 12/118 (10%)
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRV---CPHACENVVGSYICKCPEG 579
C + SF CTC G+ G C DI+EC + C C+N GSY C C G
Sbjct: 134 CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNG 189
Query: 580 YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
+ S +D C+D++EC + +C VC N G F C+C G+ + C D
Sbjct: 190 FVMLSNKKD----CKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243
>M57853-1|AAA60357.1| 676|Homo sapiens S protein protein.
Length = 676
Score = 123 bits (297), Expect = 2e-27
Identities = 65/184 (35%), Positives = 104/184 (56%), Gaps = 18/184 (9%)
Query: 461 PDGLSCVDA--DECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEG- 516
PD SCV+A D+C+ P G +C + + + C C PG+ QG ++ D++EC +
Sbjct: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGW-QG-EKCEFDINECKDPS 165
Query: 517 --RASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYI 573
C+ C NT GS+ C+C G+ + ++ C+D+DEC +P +C A C+N+ G +
Sbjct: 166 NINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFE 225
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDA--GFEPSED 631
C+CPEGYR +CEDI+EC E++C+ +C+N G + C CD GF+ ++D
Sbjct: 226 CECPEGYRYNL----KSKSCEDIDEC--SENMCA-QLCVNYPGGYTCYCDGKKGFKLAQD 278
Query: 632 GTDC 635
C
Sbjct: 279 QKSC 282
Score = 109 bits (263), Expect = 3e-23
Identities = 62/179 (34%), Positives = 90/179 (50%), Gaps = 20/179 (11%)
Query: 111 DECSWGRPPCR--GMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG-- 165
D+CS PC G C + +F C C PG++ ++CE D++EC D + G
Sbjct: 119 DQCS--PLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCS 172
Query: 166 -DCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
C NT GSY C CK G+ + N C+DVDECS +C C+N+PG + C C +G+
Sbjct: 173 QICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
Query: 223 KAG-PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCEC--APGYTLTADGRNCRDVDEC 278
+ + C D++EC E +C C N G + C C G+ L D ++C V C
Sbjct: 233 RYNLKSKSCEDIDECSEN--MCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 109 bits (261), Expect = 5e-23
Identities = 63/177 (35%), Positives = 85/177 (48%), Gaps = 20/177 (11%)
Query: 145 PSLDECEDV--DECGDQRICDHG--DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRP 200
P L C + D+C + G C++ S+ C CKPG+ E D++EC P
Sbjct: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ-GEKCEFDINECKDPSN 166
Query: 201 VCRNG----TCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSF 255
+ NG C+N PG+Y C C +GF N DC DV+EC +C C+N G F
Sbjct: 167 I--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDF 224
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA--GWKL 310
CEC GY ++C D+DEC E + C + C N GGY C C G+KL
Sbjct: 225 ECECPEGYRYNLKSKSCEDIDECSE--NMCAQ----LCVNYPGGYTCYCDGKKGFKL 275
Score = 105 bits (252), Expect = 7e-22
Identities = 51/153 (33%), Positives = 75/153 (49%), Gaps = 7/153 (4%)
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR--CVNTDGSFRCECPDGYVLAPDGLS 465
A F C+ G D++EC+ ++ G C NT GS+ C C +G+V+ +
Sbjct: 139 ASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKD 198
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG-PDQTCVDVDECAEGRASCTFRC 524
C D DEC+L P ICG C N G +EC+C G+ ++C D+DEC+E C C
Sbjct: 199 CKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSEN--MCAQLC 256
Query: 525 HNTAGSFRCTC--PYGYAVAADGVHCRDIDECV 555
N G + C C G+ +A D C + C+
Sbjct: 257 VNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCL 289
Score = 99.5 bits (237), Expect = 4e-20
Identities = 60/170 (35%), Positives = 87/170 (51%), Gaps = 21/170 (12%)
Query: 184 LRENVCRDVDECSRPRPVCRNG--TCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGG 240
LR V D+CS P P +G +C++ ++ C C G++ C D+NEC++
Sbjct: 110 LRSCVNAIPDQCS-PLPCNEDGYMSCKDGKASFTCTCKPGWQG---EKCEFDINECKDPS 165
Query: 241 MVCRNGRCR----NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
+ NG C NT GS+ C C G+ + ++ ++C+DVDEC P CG C N
Sbjct: 166 NI--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG---TAVCKNI 220
Query: 297 NGGYECSCGAGWK--LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
G +EC C G++ L + C D DEC E +CA C N+ GGY C C
Sbjct: 221 PGDFECECPEGYRYNLKSKSCEDIDECSE--NMCA-QLCVNYPGGYTCYC 267
Score = 93.1 bits (221), Expect = 4e-18
Identities = 47/117 (40%), Positives = 61/117 (52%), Gaps = 7/117 (5%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
C +TP + C C +G+ + C+DVDECS +P G A C N+PG FEC CP GYR
Sbjct: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSL-KPSICGTAVCKNIPGDFECECPEGYR 233
Query: 143 LTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCEC--KPGYTLREN--VCRDVDEC 195
CED+DEC + +C C N G Y C C K G+ L ++ C V C
Sbjct: 234 YNLKSKSCEDIDEC-SENMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 87.0 bits (206), Expect = 3e-16
Identities = 45/128 (35%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Query: 236 CREGG-MVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSC 293
C E G M C++G+ SF C C PG+ G C D++EC + P + C
Sbjct: 126 CNEDGYMSCKDGKA-----SFTCTCKPGW----QGEKCEFDINECKD-PSNINGGCSQIC 175
Query: 294 TNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFD 351
NT G Y CSC G+ ++ + C D DEC P +C C+N G + CECP G+R++
Sbjct: 176 DNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYN 235
Query: 352 KTAAVCVD 359
+ C D
Sbjct: 236 LKSKSCED 243
Score = 83.4 bits (197), Expect = 3e-15
Identities = 44/118 (37%), Positives = 63/118 (53%), Gaps = 19/118 (16%)
Query: 749 DECAAIP----GL--CAPGR--FRCVCGPGYRPAGEVCA-DVDECAVRPPP-----CDQL 794
D+C+ +P G C G+ F C C PG++ GE C D++EC + P C Q+
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ--GEKCEFDINEC--KDPSNINGGCSQI 174
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGY 851
C NT GSY C C+ G+ + + +C+DVDEC C +C N G +EC C +GY
Sbjct: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
Score = 77.8 bits (183), Expect = 2e-13
Identities = 48/157 (30%), Positives = 66/157 (42%), Gaps = 24/157 (15%)
Query: 18 QTKYLCCCSVGHAW-GAPCE----AC--PPRGSPAHTALCGEKPGEYINPVTN------- 63
+ + C C G W G CE C P + + +C PG Y N
Sbjct: 138 KASFTCTCKPG--WQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSN 195
Query: 64 --ETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
+ K +DEC + P +C C + P F+C C GY ++ S C D+DECS C
Sbjct: 196 KKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS--ENMCA 253
Query: 122 GMAQCVNLPGAFECRC--PPGYRLTPSLDECEDVDEC 156
+ CVN PG + C C G++L CE V C
Sbjct: 254 QL--CVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 77.4 bits (182), Expect = 2e-13
Identities = 39/114 (34%), Positives = 57/114 (50%), Gaps = 14/114 (12%)
Query: 747 DVDEC---AAIPGLCA------PGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQ-L 794
D++EC + I G C+ PG + C C G+ C DVDEC+++P C +
Sbjct: 157 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAV 216
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCE 848
C N G ++C C GY + +C D+DEC + C Q+C N G Y C C+
Sbjct: 217 CKNIPGDFECECPEGYRYNLKSKSCEDIDECSE--NMCAQLCVNYPGGYTCYCD 268
Score = 75.8 bits (178), Expect = 6e-13
Identities = 39/118 (33%), Positives = 54/118 (45%), Gaps = 12/118 (10%)
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRV---CPHACENVVGSYICKCPEG 579
C + SF CTC G+ G C DI+EC + C C+N GSY C C G
Sbjct: 134 CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNG 189
Query: 580 YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
+ S +D C+D++EC + +C VC N G F C+C G+ + C D
Sbjct: 190 FVMLSNKKD----CKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243
>M36564-1|AAA60180.1| 650|Homo sapiens PROS1 protein.
Length = 650
Score = 123 bits (297), Expect = 2e-27
Identities = 65/184 (35%), Positives = 104/184 (56%), Gaps = 18/184 (9%)
Query: 461 PDGLSCVDA--DECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEG- 516
PD SCV+A D+C+ P G +C + + + C C PG+ QG ++ D++EC +
Sbjct: 82 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGW-QG-EKCEFDINECKDPS 139
Query: 517 --RASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYI 573
C+ C NT GS+ C+C G+ + ++ C+D+DEC +P +C A C+N+ G +
Sbjct: 140 NINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFE 199
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDA--GFEPSED 631
C+CPEGYR +CEDI+EC E++C+ +C+N G + C CD GF+ ++D
Sbjct: 200 CECPEGYRYNL----KSKSCEDIDEC--SENMCA-QLCVNYPGGYTCYCDGKKGFKLAQD 252
Query: 632 GTDC 635
C
Sbjct: 253 QKSC 256
Score = 109 bits (263), Expect = 3e-23
Identities = 62/179 (34%), Positives = 90/179 (50%), Gaps = 20/179 (11%)
Query: 111 DECSWGRPPCR--GMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG-- 165
D+CS PC G C + +F C C PG++ ++CE D++EC D + G
Sbjct: 93 DQCS--PLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCS 146
Query: 166 -DCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
C NT GSY C CK G+ + N C+DVDECS +C C+N+PG + C C +G+
Sbjct: 147 QICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 206
Query: 223 KAG-PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCEC--APGYTLTADGRNCRDVDEC 278
+ + C D++EC E +C C N G + C C G+ L D ++C V C
Sbjct: 207 RYNLKSKSCEDIDECSEN--MCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 262
Score = 109 bits (261), Expect = 5e-23
Identities = 63/177 (35%), Positives = 85/177 (48%), Gaps = 20/177 (11%)
Query: 145 PSLDECEDV--DECGDQRICDHG--DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRP 200
P L C + D+C + G C++ S+ C CKPG+ E D++EC P
Sbjct: 82 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ-GEKCEFDINECKDPSN 140
Query: 201 VCRNG----TCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSF 255
+ NG C+N PG+Y C C +GF N DC DV+EC +C C+N G F
Sbjct: 141 I--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDF 198
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA--GWKL 310
CEC GY ++C D+DEC E + C + C N GGY C C G+KL
Sbjct: 199 ECECPEGYRYNLKSKSCEDIDECSE--NMCAQ----LCVNYPGGYTCYCDGKKGFKL 249
Score = 105 bits (252), Expect = 7e-22
Identities = 51/153 (33%), Positives = 75/153 (49%), Gaps = 7/153 (4%)
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR--CVNTDGSFRCECPDGYVLAPDGLS 465
A F C+ G D++EC+ ++ G C NT GS+ C C +G+V+ +
Sbjct: 113 ASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKD 172
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG-PDQTCVDVDECAEGRASCTFRC 524
C D DEC+L P ICG C N G +EC+C G+ ++C D+DEC+E C C
Sbjct: 173 CKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSEN--MCAQLC 230
Query: 525 HNTAGSFRCTC--PYGYAVAADGVHCRDIDECV 555
N G + C C G+ +A D C + C+
Sbjct: 231 VNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCL 263
Score = 99.5 bits (237), Expect = 4e-20
Identities = 60/170 (35%), Positives = 87/170 (51%), Gaps = 21/170 (12%)
Query: 184 LRENVCRDVDECSRPRPVCRNG--TCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGG 240
LR V D+CS P P +G +C++ ++ C C G++ C D+NEC++
Sbjct: 84 LRSCVNAIPDQCS-PLPCNEDGYMSCKDGKASFTCTCKPGWQG---EKCEFDINECKDPS 139
Query: 241 MVCRNGRCR----NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
+ NG C NT GS+ C C G+ + ++ ++C+DVDEC P CG C N
Sbjct: 140 NI--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG---TAVCKNI 194
Query: 297 NGGYECSCGAGWK--LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
G +EC C G++ L + C D DEC E +CA C N+ GGY C C
Sbjct: 195 PGDFECECPEGYRYNLKSKSCEDIDECSE--NMCA-QLCVNYPGGYTCYC 241
Score = 93.1 bits (221), Expect = 4e-18
Identities = 47/117 (40%), Positives = 61/117 (52%), Gaps = 7/117 (5%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
C +TP + C C +G+ + C+DVDECS +P G A C N+PG FEC CP GYR
Sbjct: 149 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSL-KPSICGTAVCKNIPGDFECECPEGYR 207
Query: 143 LTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCEC--KPGYTLREN--VCRDVDEC 195
CED+DEC + +C C N G Y C C K G+ L ++ C V C
Sbjct: 208 YNLKSKSCEDIDEC-SENMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 262
Score = 87.0 bits (206), Expect = 3e-16
Identities = 45/128 (35%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Query: 236 CREGG-MVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSC 293
C E G M C++G+ SF C C PG+ G C D++EC + P + C
Sbjct: 100 CNEDGYMSCKDGKA-----SFTCTCKPGW----QGEKCEFDINECKD-PSNINGGCSQIC 149
Query: 294 TNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFD 351
NT G Y CSC G+ ++ + C D DEC P +C C+N G + CECP G+R++
Sbjct: 150 DNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYN 209
Query: 352 KTAAVCVD 359
+ C D
Sbjct: 210 LKSKSCED 217
Score = 83.4 bits (197), Expect = 3e-15
Identities = 44/118 (37%), Positives = 63/118 (53%), Gaps = 19/118 (16%)
Query: 749 DECAAIP----GL--CAPGR--FRCVCGPGYRPAGEVCA-DVDECAVRPPP-----CDQL 794
D+C+ +P G C G+ F C C PG++ GE C D++EC + P C Q+
Sbjct: 93 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ--GEKCEFDINEC--KDPSNINGGCSQI 148
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGY 851
C NT GSY C C+ G+ + + +C+DVDEC C +C N G +EC C +GY
Sbjct: 149 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 206
Score = 77.8 bits (183), Expect = 2e-13
Identities = 48/157 (30%), Positives = 66/157 (42%), Gaps = 24/157 (15%)
Query: 18 QTKYLCCCSVGHAW-GAPCE----AC--PPRGSPAHTALCGEKPGEYINPVTN------- 63
+ + C C G W G CE C P + + +C PG Y N
Sbjct: 112 KASFTCTCKPG--WQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSN 169
Query: 64 --ETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
+ K +DEC + P +C C + P F+C C GY ++ S C D+DECS C
Sbjct: 170 KKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS--ENMCA 227
Query: 122 GMAQCVNLPGAFECRC--PPGYRLTPSLDECEDVDEC 156
+ CVN PG + C C G++L CE V C
Sbjct: 228 QL--CVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 262
Score = 77.4 bits (182), Expect = 2e-13
Identities = 39/114 (34%), Positives = 57/114 (50%), Gaps = 14/114 (12%)
Query: 747 DVDEC---AAIPGLCA------PGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQ-L 794
D++EC + I G C+ PG + C C G+ C DVDEC+++P C +
Sbjct: 131 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAV 190
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCE 848
C N G ++C C GY + +C D+DEC + C Q+C N G Y C C+
Sbjct: 191 CKNIPGDFECECPEGYRYNLKSKSCEDIDECSE--NMCAQLCVNYPGGYTCYCD 242
Score = 75.8 bits (178), Expect = 6e-13
Identities = 39/118 (33%), Positives = 54/118 (45%), Gaps = 12/118 (10%)
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRV---CPHACENVVGSYICKCPEG 579
C + SF CTC G+ G C DI+EC + C C+N GSY C C G
Sbjct: 108 CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNG 163
Query: 580 YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
+ S +D C+D++EC + +C VC N G F C+C G+ + C D
Sbjct: 164 FVMLSNKKD----CKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 217
>M15036-1|AAA36479.1| 676|Homo sapiens protein ( Human vitamin
K-dependent plasma protein S mRNA, complete cds. ).
Length = 676
Score = 123 bits (297), Expect = 2e-27
Identities = 65/184 (35%), Positives = 104/184 (56%), Gaps = 18/184 (9%)
Query: 461 PDGLSCVDA--DECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEG- 516
PD SCV+A D+C+ P G +C + + + C C PG+ QG ++ D++EC +
Sbjct: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGW-QG-EKCEFDINECKDPS 165
Query: 517 --RASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYI 573
C+ C NT GS+ C+C G+ + ++ C+D+DEC +P +C A C+N+ G +
Sbjct: 166 NINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFE 225
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDA--GFEPSED 631
C+CPEGYR +CEDI+EC E++C+ +C+N G + C CD GF+ ++D
Sbjct: 226 CECPEGYRYNL----KSKSCEDIDEC--SENMCA-QLCVNYPGGYTCYCDGKKGFKLAQD 278
Query: 632 GTDC 635
C
Sbjct: 279 QKSC 282
Score = 109 bits (263), Expect = 3e-23
Identities = 62/179 (34%), Positives = 90/179 (50%), Gaps = 20/179 (11%)
Query: 111 DECSWGRPPCR--GMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG-- 165
D+CS PC G C + +F C C PG++ ++CE D++EC D + G
Sbjct: 119 DQCS--PLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCS 172
Query: 166 -DCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
C NT GSY C CK G+ + N C+DVDECS +C C+N+PG + C C +G+
Sbjct: 173 QICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
Query: 223 KAG-PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCEC--APGYTLTADGRNCRDVDEC 278
+ + C D++EC E +C C N G + C C G+ L D ++C V C
Sbjct: 233 RYNLKSKSCEDIDECSEN--MCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 109 bits (261), Expect = 5e-23
Identities = 63/177 (35%), Positives = 85/177 (48%), Gaps = 20/177 (11%)
Query: 145 PSLDECEDV--DECGDQRICDHG--DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRP 200
P L C + D+C + G C++ S+ C CKPG+ E D++EC P
Sbjct: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ-GEKCEFDINECKDPSN 166
Query: 201 VCRNG----TCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSF 255
+ NG C+N PG+Y C C +GF N DC DV+EC +C C+N G F
Sbjct: 167 I--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDF 224
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA--GWKL 310
CEC GY ++C D+DEC E + C + C N GGY C C G+KL
Sbjct: 225 ECECPEGYRYNLKSKSCEDIDECSE--NMCAQ----LCVNYPGGYTCYCDGKKGFKL 275
Score = 105 bits (252), Expect = 7e-22
Identities = 51/153 (33%), Positives = 75/153 (49%), Gaps = 7/153 (4%)
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR--CVNTDGSFRCECPDGYVLAPDGLS 465
A F C+ G D++EC+ ++ G C NT GS+ C C +G+V+ +
Sbjct: 139 ASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKD 198
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG-PDQTCVDVDECAEGRASCTFRC 524
C D DEC+L P ICG C N G +EC+C G+ ++C D+DEC+E C C
Sbjct: 199 CKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSEN--MCAQLC 256
Query: 525 HNTAGSFRCTC--PYGYAVAADGVHCRDIDECV 555
N G + C C G+ +A D C + C+
Sbjct: 257 VNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCL 289
Score = 99.5 bits (237), Expect = 4e-20
Identities = 60/170 (35%), Positives = 87/170 (51%), Gaps = 21/170 (12%)
Query: 184 LRENVCRDVDECSRPRPVCRNG--TCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGG 240
LR V D+CS P P +G +C++ ++ C C G++ C D+NEC++
Sbjct: 110 LRSCVNAIPDQCS-PLPCNEDGYMSCKDGKASFTCTCKPGWQG---EKCEFDINECKDPS 165
Query: 241 MVCRNGRCR----NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
+ NG C NT GS+ C C G+ + ++ ++C+DVDEC P CG C N
Sbjct: 166 NI--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG---TAVCKNI 220
Query: 297 NGGYECSCGAGWK--LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
G +EC C G++ L + C D DEC E +CA C N+ GGY C C
Sbjct: 221 PGDFECECPEGYRYNLKSKSCEDIDECSE--NMCA-QLCVNYPGGYTCYC 267
Score = 93.1 bits (221), Expect = 4e-18
Identities = 47/117 (40%), Positives = 61/117 (52%), Gaps = 7/117 (5%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
C +TP + C C +G+ + C+DVDECS +P G A C N+PG FEC CP GYR
Sbjct: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSL-KPSICGTAVCKNIPGDFECECPEGYR 233
Query: 143 LTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCEC--KPGYTLREN--VCRDVDEC 195
CED+DEC + +C C N G Y C C K G+ L ++ C V C
Sbjct: 234 YNLKSKSCEDIDEC-SENMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 87.0 bits (206), Expect = 3e-16
Identities = 45/128 (35%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Query: 236 CREGG-MVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSC 293
C E G M C++G+ SF C C PG+ G C D++EC + P + C
Sbjct: 126 CNEDGYMSCKDGKA-----SFTCTCKPGW----QGEKCEFDINECKD-PSNINGGCSQIC 175
Query: 294 TNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFD 351
NT G Y CSC G+ ++ + C D DEC P +C C+N G + CECP G+R++
Sbjct: 176 DNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYN 235
Query: 352 KTAAVCVD 359
+ C D
Sbjct: 236 LKSKSCED 243
Score = 83.4 bits (197), Expect = 3e-15
Identities = 44/118 (37%), Positives = 63/118 (53%), Gaps = 19/118 (16%)
Query: 749 DECAAIP----GL--CAPGR--FRCVCGPGYRPAGEVCA-DVDECAVRPPP-----CDQL 794
D+C+ +P G C G+ F C C PG++ GE C D++EC + P C Q+
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ--GEKCEFDINEC--KDPSNINGGCSQI 174
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGY 851
C NT GSY C C+ G+ + + +C+DVDEC C +C N G +EC C +GY
Sbjct: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
Score = 77.8 bits (183), Expect = 2e-13
Identities = 48/157 (30%), Positives = 66/157 (42%), Gaps = 24/157 (15%)
Query: 18 QTKYLCCCSVGHAW-GAPCE----AC--PPRGSPAHTALCGEKPGEYINPVTN------- 63
+ + C C G W G CE C P + + +C PG Y N
Sbjct: 138 KASFTCTCKPG--WQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSN 195
Query: 64 --ETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
+ K +DEC + P +C C + P F+C C GY ++ S C D+DECS C
Sbjct: 196 KKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS--ENMCA 253
Query: 122 GMAQCVNLPGAFECRC--PPGYRLTPSLDECEDVDEC 156
+ CVN PG + C C G++L CE V C
Sbjct: 254 QL--CVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 77.4 bits (182), Expect = 2e-13
Identities = 39/114 (34%), Positives = 57/114 (50%), Gaps = 14/114 (12%)
Query: 747 DVDEC---AAIPGLCA------PGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQ-L 794
D++EC + I G C+ PG + C C G+ C DVDEC+++P C +
Sbjct: 157 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAV 216
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCE 848
C N G ++C C GY + +C D+DEC + C Q+C N G Y C C+
Sbjct: 217 CKNIPGDFECECPEGYRYNLKSKSCEDIDECSE--NMCAQLCVNYPGGYTCYCD 268
Score = 75.8 bits (178), Expect = 6e-13
Identities = 39/118 (33%), Positives = 54/118 (45%), Gaps = 12/118 (10%)
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRV---CPHACENVVGSYICKCPEG 579
C + SF CTC G+ G C DI+EC + C C+N GSY C C G
Sbjct: 134 CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNG 189
Query: 580 YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
+ S +D C+D++EC + +C VC N G F C+C G+ + C D
Sbjct: 190 FVMLSNKKD----CKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243
>BC015801-1|AAH15801.1| 676|Homo sapiens PROS1 protein protein.
Length = 676
Score = 123 bits (297), Expect = 2e-27
Identities = 65/184 (35%), Positives = 104/184 (56%), Gaps = 18/184 (9%)
Query: 461 PDGLSCVDA--DECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEG- 516
PD SCV+A D+C+ P G +C + + + C C PG+ QG ++ D++EC +
Sbjct: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGW-QG-EKCEFDINECKDPS 165
Query: 517 --RASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYI 573
C+ C NT GS+ C+C G+ + ++ C+D+DEC +P +C A C+N+ G +
Sbjct: 166 NINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFE 225
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDA--GFEPSED 631
C+CPEGYR +CEDI+EC E++C+ +C+N G + C CD GF+ ++D
Sbjct: 226 CECPEGYRYNL----KSKSCEDIDEC--SENMCA-QLCVNYPGGYTCYCDGKKGFKLAQD 278
Query: 632 GTDC 635
C
Sbjct: 279 QKSC 282
Score = 109 bits (263), Expect = 3e-23
Identities = 62/179 (34%), Positives = 90/179 (50%), Gaps = 20/179 (11%)
Query: 111 DECSWGRPPCR--GMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG-- 165
D+CS PC G C + +F C C PG++ ++CE D++EC D + G
Sbjct: 119 DQCS--PLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCS 172
Query: 166 -DCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
C NT GSY C CK G+ + N C+DVDECS +C C+N+PG + C C +G+
Sbjct: 173 QICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
Query: 223 KAG-PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCEC--APGYTLTADGRNCRDVDEC 278
+ + C D++EC E +C C N G + C C G+ L D ++C V C
Sbjct: 233 RYNLKSKSCEDIDECSEN--MCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 109 bits (261), Expect = 5e-23
Identities = 63/177 (35%), Positives = 85/177 (48%), Gaps = 20/177 (11%)
Query: 145 PSLDECEDV--DECGDQRICDHG--DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRP 200
P L C + D+C + G C++ S+ C CKPG+ E D++EC P
Sbjct: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ-GEKCEFDINECKDPSN 166
Query: 201 VCRNG----TCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSF 255
+ NG C+N PG+Y C C +GF N DC DV+EC +C C+N G F
Sbjct: 167 I--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDF 224
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA--GWKL 310
CEC GY ++C D+DEC E + C + C N GGY C C G+KL
Sbjct: 225 ECECPEGYRYNLKSKSCEDIDECSE--NMCAQ----LCVNYPGGYTCYCDGKKGFKL 275
Score = 105 bits (252), Expect = 7e-22
Identities = 51/153 (33%), Positives = 75/153 (49%), Gaps = 7/153 (4%)
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR--CVNTDGSFRCECPDGYVLAPDGLS 465
A F C+ G D++EC+ ++ G C NT GS+ C C +G+V+ +
Sbjct: 139 ASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKD 198
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG-PDQTCVDVDECAEGRASCTFRC 524
C D DEC+L P ICG C N G +EC+C G+ ++C D+DEC+E C C
Sbjct: 199 CKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSEN--MCAQLC 256
Query: 525 HNTAGSFRCTC--PYGYAVAADGVHCRDIDECV 555
N G + C C G+ +A D C + C+
Sbjct: 257 VNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCL 289
Score = 99.5 bits (237), Expect = 4e-20
Identities = 60/170 (35%), Positives = 87/170 (51%), Gaps = 21/170 (12%)
Query: 184 LRENVCRDVDECSRPRPVCRNG--TCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGG 240
LR V D+CS P P +G +C++ ++ C C G++ C D+NEC++
Sbjct: 110 LRSCVNAIPDQCS-PLPCNEDGYMSCKDGKASFTCTCKPGWQG---EKCEFDINECKDPS 165
Query: 241 MVCRNGRCR----NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
+ NG C NT GS+ C C G+ + ++ ++C+DVDEC P CG C N
Sbjct: 166 NI--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG---TAVCKNI 220
Query: 297 NGGYECSCGAGWK--LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
G +EC C G++ L + C D DEC E +CA C N+ GGY C C
Sbjct: 221 PGDFECECPEGYRYNLKSKSCEDIDECSE--NMCA-QLCVNYPGGYTCYC 267
Score = 93.1 bits (221), Expect = 4e-18
Identities = 47/117 (40%), Positives = 61/117 (52%), Gaps = 7/117 (5%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
C +TP + C C +G+ + C+DVDECS +P G A C N+PG FEC CP GYR
Sbjct: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSL-KPSICGTAVCKNIPGDFECECPEGYR 233
Query: 143 LTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCEC--KPGYTLREN--VCRDVDEC 195
CED+DEC + +C C N G Y C C K G+ L ++ C V C
Sbjct: 234 YNLKSKSCEDIDEC-SENMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 87.0 bits (206), Expect = 3e-16
Identities = 45/128 (35%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Query: 236 CREGG-MVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSC 293
C E G M C++G+ SF C C PG+ G C D++EC + P + C
Sbjct: 126 CNEDGYMSCKDGKA-----SFTCTCKPGW----QGEKCEFDINECKD-PSNINGGCSQIC 175
Query: 294 TNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFD 351
NT G Y CSC G+ ++ + C D DEC P +C C+N G + CECP G+R++
Sbjct: 176 DNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYN 235
Query: 352 KTAAVCVD 359
+ C D
Sbjct: 236 LKSKSCED 243
Score = 83.4 bits (197), Expect = 3e-15
Identities = 44/118 (37%), Positives = 63/118 (53%), Gaps = 19/118 (16%)
Query: 749 DECAAIP----GL--CAPGR--FRCVCGPGYRPAGEVCA-DVDECAVRPPP-----CDQL 794
D+C+ +P G C G+ F C C PG++ GE C D++EC + P C Q+
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ--GEKCEFDINEC--KDPSNINGGCSQI 174
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGY 851
C NT GSY C C+ G+ + + +C+DVDEC C +C N G +EC C +GY
Sbjct: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
Score = 77.8 bits (183), Expect = 2e-13
Identities = 48/157 (30%), Positives = 66/157 (42%), Gaps = 24/157 (15%)
Query: 18 QTKYLCCCSVGHAW-GAPCE----AC--PPRGSPAHTALCGEKPGEYINPVTN------- 63
+ + C C G W G CE C P + + +C PG Y N
Sbjct: 138 KASFTCTCKPG--WQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSN 195
Query: 64 --ETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
+ K +DEC + P +C C + P F+C C GY ++ S C D+DECS C
Sbjct: 196 KKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS--ENMCA 253
Query: 122 GMAQCVNLPGAFECRC--PPGYRLTPSLDECEDVDEC 156
+ CVN PG + C C G++L CE V C
Sbjct: 254 QL--CVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 77.4 bits (182), Expect = 2e-13
Identities = 39/114 (34%), Positives = 57/114 (50%), Gaps = 14/114 (12%)
Query: 747 DVDEC---AAIPGLCA------PGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQ-L 794
D++EC + I G C+ PG + C C G+ C DVDEC+++P C +
Sbjct: 157 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAV 216
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCE 848
C N G ++C C GY + +C D+DEC + C Q+C N G Y C C+
Sbjct: 217 CKNIPGDFECECPEGYRYNLKSKSCEDIDECSE--NMCAQLCVNYPGGYTCYCD 268
Score = 75.8 bits (178), Expect = 6e-13
Identities = 39/118 (33%), Positives = 54/118 (45%), Gaps = 12/118 (10%)
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRV---CPHACENVVGSYICKCPEG 579
C + SF CTC G+ G C DI+EC + C C+N GSY C C G
Sbjct: 134 CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNG 189
Query: 580 YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
+ S +D C+D++EC + +C VC N G F C+C G+ + C D
Sbjct: 190 FVMLSNKKD----CKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243
>AY308744-1|AAP45054.1| 497|Homo sapiens protein S (alpha) protein.
Length = 497
Score = 123 bits (297), Expect = 2e-27
Identities = 65/184 (35%), Positives = 104/184 (56%), Gaps = 18/184 (9%)
Query: 461 PDGLSCVDA--DECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEG- 516
PD SCV+A D+C+ P G +C + + + C C PG+ QG ++ D++EC +
Sbjct: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGW-QG-EKCEFDINECKDPS 165
Query: 517 --RASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYI 573
C+ C NT GS+ C+C G+ + ++ C+D+DEC +P +C A C+N+ G +
Sbjct: 166 NINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFE 225
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDA--GFEPSED 631
C+CPEGYR +CEDI+EC E++C+ +C+N G + C CD GF+ ++D
Sbjct: 226 CECPEGYRYNL----KSKSCEDIDEC--SENMCA-QLCVNYPGGYTCYCDGKKGFKLAQD 278
Query: 632 GTDC 635
C
Sbjct: 279 QKSC 282
Score = 109 bits (263), Expect = 3e-23
Identities = 62/179 (34%), Positives = 90/179 (50%), Gaps = 20/179 (11%)
Query: 111 DECSWGRPPCR--GMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG-- 165
D+CS PC G C + +F C C PG++ ++CE D++EC D + G
Sbjct: 119 DQCS--PLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCS 172
Query: 166 -DCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
C NT GSY C CK G+ + N C+DVDECS +C C+N+PG + C C +G+
Sbjct: 173 QICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
Query: 223 KAG-PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCEC--APGYTLTADGRNCRDVDEC 278
+ + C D++EC E +C C N G + C C G+ L D ++C V C
Sbjct: 233 RYNLKSKSCEDIDECSEN--MCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 109 bits (261), Expect = 5e-23
Identities = 63/177 (35%), Positives = 85/177 (48%), Gaps = 20/177 (11%)
Query: 145 PSLDECEDV--DECGDQRICDHG--DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRP 200
P L C + D+C + G C++ S+ C CKPG+ E D++EC P
Sbjct: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ-GEKCEFDINECKDPSN 166
Query: 201 VCRNG----TCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSF 255
+ NG C+N PG+Y C C +GF N DC DV+EC +C C+N G F
Sbjct: 167 I--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDF 224
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA--GWKL 310
CEC GY ++C D+DEC E + C + C N GGY C C G+KL
Sbjct: 225 ECECPEGYRYNLKSKSCEDIDECSE--NMCAQ----LCVNYPGGYTCYCDGKKGFKL 275
Score = 105 bits (252), Expect = 7e-22
Identities = 51/153 (33%), Positives = 75/153 (49%), Gaps = 7/153 (4%)
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR--CVNTDGSFRCECPDGYVLAPDGLS 465
A F C+ G D++EC+ ++ G C NT GS+ C C +G+V+ +
Sbjct: 139 ASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKD 198
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG-PDQTCVDVDECAEGRASCTFRC 524
C D DEC+L P ICG C N G +EC+C G+ ++C D+DEC+E C C
Sbjct: 199 CKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSEN--MCAQLC 256
Query: 525 HNTAGSFRCTC--PYGYAVAADGVHCRDIDECV 555
N G + C C G+ +A D C + C+
Sbjct: 257 VNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCL 289
Score = 99.5 bits (237), Expect = 4e-20
Identities = 60/170 (35%), Positives = 87/170 (51%), Gaps = 21/170 (12%)
Query: 184 LRENVCRDVDECSRPRPVCRNG--TCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGG 240
LR V D+CS P P +G +C++ ++ C C G++ C D+NEC++
Sbjct: 110 LRSCVNAIPDQCS-PLPCNEDGYMSCKDGKASFTCTCKPGWQG---EKCEFDINECKDPS 165
Query: 241 MVCRNGRCR----NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
+ NG C NT GS+ C C G+ + ++ ++C+DVDEC P CG C N
Sbjct: 166 NI--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG---TAVCKNI 220
Query: 297 NGGYECSCGAGWK--LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
G +EC C G++ L + C D DEC E +CA C N+ GGY C C
Sbjct: 221 PGDFECECPEGYRYNLKSKSCEDIDECSE--NMCA-QLCVNYPGGYTCYC 267
Score = 93.1 bits (221), Expect = 4e-18
Identities = 47/117 (40%), Positives = 61/117 (52%), Gaps = 7/117 (5%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
C +TP + C C +G+ + C+DVDECS +P G A C N+PG FEC CP GYR
Sbjct: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSL-KPSICGTAVCKNIPGDFECECPEGYR 233
Query: 143 LTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCEC--KPGYTLREN--VCRDVDEC 195
CED+DEC + +C C N G Y C C K G+ L ++ C V C
Sbjct: 234 YNLKSKSCEDIDEC-SENMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 87.0 bits (206), Expect = 3e-16
Identities = 45/128 (35%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Query: 236 CREGG-MVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSC 293
C E G M C++G+ SF C C PG+ G C D++EC + P + C
Sbjct: 126 CNEDGYMSCKDGKA-----SFTCTCKPGW----QGEKCEFDINECKD-PSNINGGCSQIC 175
Query: 294 TNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFD 351
NT G Y CSC G+ ++ + C D DEC P +C C+N G + CECP G+R++
Sbjct: 176 DNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYN 235
Query: 352 KTAAVCVD 359
+ C D
Sbjct: 236 LKSKSCED 243
Score = 83.4 bits (197), Expect = 3e-15
Identities = 44/118 (37%), Positives = 63/118 (53%), Gaps = 19/118 (16%)
Query: 749 DECAAIP----GL--CAPGR--FRCVCGPGYRPAGEVCA-DVDECAVRPPP-----CDQL 794
D+C+ +P G C G+ F C C PG++ GE C D++EC + P C Q+
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ--GEKCEFDINEC--KDPSNINGGCSQI 174
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGY 851
C NT GSY C C+ G+ + + +C+DVDEC C +C N G +EC C +GY
Sbjct: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
Score = 77.8 bits (183), Expect = 2e-13
Identities = 48/157 (30%), Positives = 66/157 (42%), Gaps = 24/157 (15%)
Query: 18 QTKYLCCCSVGHAW-GAPCE----AC--PPRGSPAHTALCGEKPGEYINPVTN------- 63
+ + C C G W G CE C P + + +C PG Y N
Sbjct: 138 KASFTCTCKPG--WQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSN 195
Query: 64 --ETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
+ K +DEC + P +C C + P F+C C GY ++ S C D+DECS C
Sbjct: 196 KKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS--ENMCA 253
Query: 122 GMAQCVNLPGAFECRC--PPGYRLTPSLDECEDVDEC 156
+ CVN PG + C C G++L CE V C
Sbjct: 254 QL--CVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 77.4 bits (182), Expect = 2e-13
Identities = 39/114 (34%), Positives = 57/114 (50%), Gaps = 14/114 (12%)
Query: 747 DVDEC---AAIPGLCA------PGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQ-L 794
D++EC + I G C+ PG + C C G+ C DVDEC+++P C +
Sbjct: 157 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAV 216
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCE 848
C N G ++C C GY + +C D+DEC + C Q+C N G Y C C+
Sbjct: 217 CKNIPGDFECECPEGYRYNLKSKSCEDIDECSE--NMCAQLCVNYPGGYTCYCD 268
Score = 75.8 bits (178), Expect = 6e-13
Identities = 39/118 (33%), Positives = 54/118 (45%), Gaps = 12/118 (10%)
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRV---CPHACENVVGSYICKCPEG 579
C + SF CTC G+ G C DI+EC + C C+N GSY C C G
Sbjct: 134 CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNG 189
Query: 580 YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
+ S +D C+D++EC + +C VC N G F C+C G+ + C D
Sbjct: 190 FVMLSNKKD----CKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243
>AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 123 bits (297), Expect = 2e-27
Identities = 115/364 (31%), Positives = 147/364 (40%), Gaps = 68/364 (18%)
Query: 283 HPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECK---ELPYVCA-GGECRNFN 337
+PC G +C N + + C C WK G C D +EC+ P C GG C N
Sbjct: 139 NPCQNGG--TCLNLHDSFFCICPPQWK--GPLCSADVNECEIYSGTPLSCQNGGTCVNTM 194
Query: 338 GGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGR 397
G Y C CP + C + YD+ E G R C G
Sbjct: 195 GSYSCHCPP----ETYGPQCASK-----YDDCEGGSVAR------------CVHGICEDL 233
Query: 398 YCERCPAPDSAEFMRICQGG-MGRPN---LTQDLDECRVRPDVCVG-GRCVNTDGSFRC- 451
E+ P ++ +C G M PN T D DEC +P C +C NT GSF C
Sbjct: 234 MREQAGEP---KYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCG 290
Query: 452 ECPDGYVLAPDGLSCVDADECALDPRICGNGT---CSNTRGGYECQ-CSPGFTQGPDQTC 507
CP G+ +G C D +EC ++ C C NT G CQ C PG+ QG + C
Sbjct: 291 ACPTGW--QGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY-QGDGRVC 347
Query: 508 VDVDECAEGRASC--TFRCHNTAGSFR-CTCPYGYAVAADGVHCRDIDECVQEPRVC-PH 563
D C+ C C +T GS CTC GY G + CVQ +C H
Sbjct: 348 TLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPN-----GCVQLSNICLSH 402
Query: 564 ACEN-----VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSF 618
C N V Y CKC G+ N E+INEC L +GG C++ SF
Sbjct: 403 PCLNGQCIDTVSGYFCKCDSGWTGV-------NCTENINECLSNPCL-NGGTCVDGVDSF 454
Query: 619 LCDC 622
C+C
Sbjct: 455 SCEC 458
Score = 120 bits (290), Expect = 2e-26
Identities = 106/357 (29%), Positives = 151/357 (42%), Gaps = 62/357 (17%)
Query: 243 CRNG-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECD---ELPHPCGRDGNPSCTNTN 297
C+NG C N SF C C P + G C DV+EC+ P C G +C NT
Sbjct: 141 CQNGGTCLNLHDSFFCICPPQWK----GPLCSADVNECEIYSGTPLSCQNGG--TCVNTM 194
Query: 298 GGYECSCGAGWKLVGRRCVDR-DECKELPYV-CAGGECRNF---NGG---YVCECPAGWR 349
G Y C C + G +C + D+C+ C G C + G Y C C AGW
Sbjct: 195 GSYSCHCPP--ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWM 252
Query: 350 FDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAE 409
F + C +R E C ++ G C +C ++G+ YC CP
Sbjct: 253 FSPNSPACTLDRDE-C--SFQPGPCS-------TLVQCFNTQGSF---YCGACPT----- 294
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVGG---RCVNTDGSFRCE-CPDGYVLAPDGLS 465
G G + +D++EC + C CVNT GS C+ CP GY DG
Sbjct: 295 ------GWQGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QGDGRV 346
Query: 466 CVDADECALDPRIC-GNGTCSNTRGGYE-CQCSPGFT---QGPDQTCVDVDECAEGRASC 520
C D C++ C + +CS+T G C C PG+T GP+ CV +
Sbjct: 347 CTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPN-GCVQLSNICLSHPCL 405
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVCPHACENVVGSYICKC 576
+C +T + C C G+ GV+C +I+EC+ P + C + V S+ C+C
Sbjct: 406 NGQCIDTVSGYFCKCDSGWT----GVNCTENINECLSNPCLNGGTCVDGVDSFSCEC 458
Score = 119 bits (286), Expect = 5e-26
Identities = 91/275 (33%), Positives = 127/275 (46%), Gaps = 31/275 (11%)
Query: 90 FQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFEC-RCPPGYRLTPSL 147
+ C CD G+ S C D DECS+ PC + QC N G+F C CP G++ +
Sbjct: 243 YSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYI 302
Query: 148 DECEDVDEC----GDQRICDHGDCRNTIGSYRCE-CKPGYTLRENVCRDVDECSRPRPVC 202
CED++EC G + +C NT GS C+ C PGY VC D CS C
Sbjct: 303 --CEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGC 360
Query: 203 R-NGTCENLPGAY-LCHCDDGFKA---GPNNDCVDV-NECREGGMVCRNGRCRNTVGSFR 256
+ +C + G+ LC C G+ GPN CV + N C C NG+C +TV +
Sbjct: 361 HPDASCSSTLGSLPLCTCLPGYTGNGYGPNG-CVQLSNICL--SHPCLNGQCIDTVSGYF 417
Query: 257 CECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
C+C G+T G NC +++EC L +PC G +C + + C C W G C
Sbjct: 418 CKCDSGWT----GVNCTENINEC--LSNPCLNGG--TCVDGVDSFSCECTRLW--TGALC 467
Query: 316 -VDRDECKE-LPYVCAGGECRNFNGGYVCECPAGW 348
V + C E L + R+ + GYV + W
Sbjct: 468 QVPQQVCGESLSGINGSFSYRSPDVGYVHDVNCFW 502
Score = 114 bits (275), Expect = 1e-24
Identities = 111/385 (28%), Positives = 157/385 (40%), Gaps = 61/385 (15%)
Query: 147 LDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECS--RPRPV-C 202
L + D C + G C N S+ C C P + + +C DV+EC P+ C
Sbjct: 127 LQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQW--KGPLCSADVNECEIYSGTPLSC 184
Query: 203 RNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMV--CRNGRC----RNTVGS- 254
+NG TC N G+Y CHC GP C + EGG V C +G C R G
Sbjct: 185 QNGGTCVNTMGSYSCHCPPE-TYGPQ--CASKYDDCEGGSVARCVHGICEDLMREQAGEP 241
Query: 255 -FRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYEC-SCGAGWKLV 311
+ C C G+ + + C D DEC P PC C NT G + C +C GW+
Sbjct: 242 KYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCST--LVQCFNTQGSFYCGACPTGWQGN 299
Query: 312 GRRCVDRDECKELPYVCAGG---ECRNFNGGYVCE-CPAGWRFDKTAAVCVDERKELCYD 367
G C D +EC+ C+ EC N G C+ CP G++ D D +C
Sbjct: 300 GYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTD----IC-- 353
Query: 368 EWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDL 427
G CH P+ CS C P G G Q
Sbjct: 354 SVSNGGCH---------PDASCSSTLGSLPLCTCLPGYTG--------NGYGPNGCVQLS 396
Query: 428 DECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD-ADECALDPRICGNGTCSN 486
+ C P C+ G+C++T + C+C G+ G++C + +EC +P + G GTC +
Sbjct: 397 NICLSHP--CLNGQCIDTVSGYFCKCDSGWT----GVNCTENINECLSNPCLNG-GTCVD 449
Query: 487 TRGGYECQCSPGFT----QGPDQTC 507
+ C+C+ +T Q P Q C
Sbjct: 450 GVDSFSCECTRLWTGALCQVPQQVC 474
Score = 107 bits (256), Expect = 2e-22
Identities = 96/360 (26%), Positives = 138/360 (38%), Gaps = 49/360 (13%)
Query: 313 RRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEA 371
++ VD+ C P C GG C N + + C CP W+ LC +
Sbjct: 128 QQTVDKKVCSSNP--CQNGGTCLNLHDSFFCICPPQWK------------GPLCSADVNE 173
Query: 372 GRCHRARPLQLARPECCCSEGAAWGRYCE-RCPAPDSAEFMRICQGGMGRPNLTQDLDEC 430
+ PL C + ++ +C P A C+GG + E
Sbjct: 174 CEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGG-SVARCVHGICED 232
Query: 431 RVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGT-CSNTR 488
+R + + C C G++ +P+ +C +D DEC+ P C C NT+
Sbjct: 233 LMREQA--------GEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQ 284
Query: 489 GGYECQCSPGFTQGPDQTCVDVDECAEGRASCT----FRCHNTAGSFRC-TCPYGYAVAA 543
G + C P QG C D++EC C+ C NT GS C CP GY
Sbjct: 285 GSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QG 342
Query: 544 DGVHCRDIDECVQEPRVC-PHA-CENVVGSY-ICKCPEGYRRTSAPQDSENACEDI-NEC 599
DG C D C C P A C + +GS +C C GY N C + N C
Sbjct: 343 DGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGY---GPNGCVQLSNIC 399
Query: 600 EEQEDLCSGGVCINTDGSFLCDCDAGF---EPSEDGTDCIDR---RTGTCYRSLVSGRCE 653
C G CI+T + C CD+G+ +E+ +C+ GTC + S CE
Sbjct: 400 LSHP--CLNGQCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCE 457
Score = 106 bits (254), Expect = 4e-22
Identities = 105/367 (28%), Positives = 150/367 (40%), Gaps = 54/367 (14%)
Query: 106 LCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR---LTPSLDECEDVDECGDQRIC 162
L + VD+ PC+ C+NL +F C CPP ++ + ++ECE G C
Sbjct: 127 LQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYS--GTPLSC 184
Query: 163 DH-GDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPV-CRNGTCENL------PGAY 214
+ G C NT+GSY C C P T D+C C +G CE+L Y
Sbjct: 185 QNGGTCVNTMGSYSCHCPP-ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKY 243
Query: 215 LCHCDDGFKAGPNNDC--VDVNECR-EGGMVCRNGRCRNTVGSFRC-ECAPGYTLTADGR 270
C CD G+ PN+ +D +EC + G +C NT GSF C C G+ +G
Sbjct: 244 SCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGW--QGNGY 301
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYEC-SCGAGWKLVGRRCVDRDECKELPYVC- 328
C D++EC+ C C NT G C +C G++ GR C D C C
Sbjct: 302 ICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCH 361
Query: 329 AGGECRNFNGGY-VCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPEC 387
C + G +C C G+ + + C + + L+ P
Sbjct: 362 PDASCSSTLGSLPLCTCLPGY----------------TGNGYGPNGCVQLSNICLSHP-- 403
Query: 388 CCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTD 446
C G +C S F + G G N T++++EC P C+ GG CV+
Sbjct: 404 -CLNG--------QCIDTVSGYFCKCDSGWTG-VNCTENINECLSNP--CLNGGTCVDGV 451
Query: 447 GSFRCEC 453
SF CEC
Sbjct: 452 DSFSCEC 458
Score = 58.4 bits (135), Expect = 1e-07
Identities = 43/126 (34%), Positives = 54/126 (42%), Gaps = 19/126 (15%)
Query: 747 DVDECAAIPGLCAP--------GRFRC-VCGPGYRPAGEVCADVDECAVRPPPCDQL--- 794
D DEC+ PG C+ G F C C G++ G +C D++EC + C
Sbjct: 263 DRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPV 322
Query: 795 -CHNTDGSYDC-LCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYE-CSCED 849
C NT GS C C GY+ DG C D C C CS+T GS C+C
Sbjct: 323 ECVNTPGSSHCQACPPGYQ--GDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLP 380
Query: 850 GYEKRG 855
GY G
Sbjct: 381 GYTGNG 386
Score = 50.0 bits (114), Expect = 4e-05
Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 9/99 (9%)
Query: 760 PGRFRC-VCGPGYRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYD-CLCRTGYELDED 815
PG C C PGY+ G VC D C+V C D C +T GS C C GY +
Sbjct: 328 PGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGY 387
Query: 816 GAN-CRDVDE-CERDTHTC-QQICSNTEGSYECSCEDGY 851
G N C + C +H C C +T Y C C+ G+
Sbjct: 388 GPNGCVQLSNICL--SHPCLNGQCIDTVSGYFCKCDSGW 424
Score = 44.0 bits (99), Expect = 0.002
Identities = 46/152 (30%), Positives = 61/152 (40%), Gaps = 26/152 (17%)
Query: 501 QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDEC---VQ 556
QG QT VD C+ C N SF C CP + G C D++EC
Sbjct: 125 QGLQQT-VDKKVCSSNPCQNGGTCLNLHDSFFCICPPQW----KGPLCSADVNECEIYSG 179
Query: 557 EPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENACEDINECE-EQEDLCSGGVCIN 613
P C + C N +GSY C CP T PQ ++CE C G+C +
Sbjct: 180 TPLSCQNGGTCVNTMGSYSCHCPP---ETYGPQ----CASKYDDCEGGSVARCVHGICED 232
Query: 614 T------DGSFLCDCDAGFEPSEDGTDC-IDR 638
+ + C CDAG+ S + C +DR
Sbjct: 233 LMREQAGEPKYSCVCDAGWMFSPNSPACTLDR 264
Score = 39.9 bits (89), Expect = 0.038
Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 5/60 (8%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRC 137
C G C DT +G+ C CD G+ N + +++EC PC CV+ +F C C
Sbjct: 404 CLNGQCIDTVSGYFCKCDSGWTGVNCT---ENINECL--SNPCLNGGTCVDGVDSFSCEC 458
Score = 36.7 bits (81), Expect = 0.35
Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 12/75 (16%)
Query: 781 VDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHT---CQQ 834
VD+ PC C N S+ C+C ++ G C DV+ECE + T CQ
Sbjct: 131 VDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWK----GPLCSADVNECEIYSGTPLSCQN 186
Query: 835 --ICSNTEGSYECSC 847
C NT GSY C C
Sbjct: 187 GGTCVNTMGSYSCHC 201
>AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 123 bits (297), Expect = 2e-27
Identities = 115/364 (31%), Positives = 147/364 (40%), Gaps = 68/364 (18%)
Query: 283 HPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECK---ELPYVCA-GGECRNFN 337
+PC G +C N + + C C WK G C D +EC+ P C GG C N
Sbjct: 139 NPCQNGG--TCLNLHDSFFCICPPQWK--GPLCSADVNECEIYSGTPLSCQNGGTCVNTM 194
Query: 338 GGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGR 397
G Y C CP + C + YD+ E G R C G
Sbjct: 195 GSYSCHCPP----ETYGPQCASK-----YDDCEGGSVAR------------CVHGICEDL 233
Query: 398 YCERCPAPDSAEFMRICQGG-MGRPN---LTQDLDECRVRPDVCVG-GRCVNTDGSFRC- 451
E+ P ++ +C G M PN T D DEC +P C +C NT GSF C
Sbjct: 234 MREQAGEP---KYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCG 290
Query: 452 ECPDGYVLAPDGLSCVDADECALDPRICGNGT---CSNTRGGYECQ-CSPGFTQGPDQTC 507
CP G+ +G C D +EC ++ C C NT G CQ C PG+ QG + C
Sbjct: 291 ACPTGW--QGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY-QGDGRVC 347
Query: 508 VDVDECAEGRASC--TFRCHNTAGSFR-CTCPYGYAVAADGVHCRDIDECVQEPRVC-PH 563
D C+ C C +T GS CTC GY G + CVQ +C H
Sbjct: 348 TLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPN-----GCVQLSNICLSH 402
Query: 564 ACEN-----VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSF 618
C N V Y CKC G+ N E+INEC L +GG C++ SF
Sbjct: 403 PCLNGQCIDTVSGYFCKCDSGWTGV-------NCTENINECLSNPCL-NGGTCVDGVDSF 454
Query: 619 LCDC 622
C+C
Sbjct: 455 SCEC 458
Score = 120 bits (290), Expect = 2e-26
Identities = 106/357 (29%), Positives = 151/357 (42%), Gaps = 62/357 (17%)
Query: 243 CRNG-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECD---ELPHPCGRDGNPSCTNTN 297
C+NG C N SF C C P + G C DV+EC+ P C G +C NT
Sbjct: 141 CQNGGTCLNLHDSFFCICPPQWK----GPLCSADVNECEIYSGTPLSCQNGG--TCVNTM 194
Query: 298 GGYECSCGAGWKLVGRRCVDR-DECKELPYV-CAGGECRNF---NGG---YVCECPAGWR 349
G Y C C + G +C + D+C+ C G C + G Y C C AGW
Sbjct: 195 GSYSCHCPP--ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWM 252
Query: 350 FDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAE 409
F + C +R E C ++ G C +C ++G+ YC CP
Sbjct: 253 FSPNSPACTLDRDE-C--SFQPGPCS-------TLVQCFNTQGSF---YCGACPT----- 294
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVGG---RCVNTDGSFRCE-CPDGYVLAPDGLS 465
G G + +D++EC + C CVNT GS C+ CP GY DG
Sbjct: 295 ------GWQGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QGDGRV 346
Query: 466 CVDADECALDPRIC-GNGTCSNTRGGYE-CQCSPGFT---QGPDQTCVDVDECAEGRASC 520
C D C++ C + +CS+T G C C PG+T GP+ CV +
Sbjct: 347 CTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPN-GCVQLSNICLSHPCL 405
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVCPHACENVVGSYICKC 576
+C +T + C C G+ GV+C +I+EC+ P + C + V S+ C+C
Sbjct: 406 NGQCIDTVSGYFCKCDSGWT----GVNCTENINECLSNPCLNGGTCVDGVDSFSCEC 458
Score = 119 bits (286), Expect = 5e-26
Identities = 91/275 (33%), Positives = 127/275 (46%), Gaps = 31/275 (11%)
Query: 90 FQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFEC-RCPPGYRLTPSL 147
+ C CD G+ S C D DECS+ PC + QC N G+F C CP G++ +
Sbjct: 243 YSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYI 302
Query: 148 DECEDVDEC----GDQRICDHGDCRNTIGSYRCE-CKPGYTLRENVCRDVDECSRPRPVC 202
CED++EC G + +C NT GS C+ C PGY VC D CS C
Sbjct: 303 --CEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGC 360
Query: 203 R-NGTCENLPGAY-LCHCDDGFKA---GPNNDCVDV-NECREGGMVCRNGRCRNTVGSFR 256
+ +C + G+ LC C G+ GPN CV + N C C NG+C +TV +
Sbjct: 361 HPDASCSSTLGSLPLCTCLPGYTGNGYGPNG-CVQLSNICL--SHPCLNGQCIDTVSGYF 417
Query: 257 CECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
C+C G+T G NC +++EC L +PC G +C + + C C W G C
Sbjct: 418 CKCDSGWT----GVNCTENINEC--LSNPCLNGG--TCVDGVDSFSCECTRLW--TGALC 467
Query: 316 -VDRDECKE-LPYVCAGGECRNFNGGYVCECPAGW 348
V + C E L + R+ + GYV + W
Sbjct: 468 QVPQQVCGESLSGINGSFSYRSPDVGYVHDVNCFW 502
Score = 114 bits (275), Expect = 1e-24
Identities = 111/385 (28%), Positives = 157/385 (40%), Gaps = 61/385 (15%)
Query: 147 LDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECS--RPRPV-C 202
L + D C + G C N S+ C C P + + +C DV+EC P+ C
Sbjct: 127 LQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQW--KGPLCSADVNECEIYSGTPLSC 184
Query: 203 RNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMV--CRNGRC----RNTVGS- 254
+NG TC N G+Y CHC GP C + EGG V C +G C R G
Sbjct: 185 QNGGTCVNTMGSYSCHCPPE-TYGPQ--CASKYDDCEGGSVARCVHGICEDLMREQAGEP 241
Query: 255 -FRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYEC-SCGAGWKLV 311
+ C C G+ + + C D DEC P PC C NT G + C +C GW+
Sbjct: 242 KYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCST--LVQCFNTQGSFYCGACPTGWQGN 299
Query: 312 GRRCVDRDECKELPYVCAGG---ECRNFNGGYVCE-CPAGWRFDKTAAVCVDERKELCYD 367
G C D +EC+ C+ EC N G C+ CP G++ D D +C
Sbjct: 300 GYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTD----IC-- 353
Query: 368 EWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDL 427
G CH P+ CS C P G G Q
Sbjct: 354 SVSNGGCH---------PDASCSSTLGSLPLCTCLPGYTG--------NGYGPNGCVQLS 396
Query: 428 DECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD-ADECALDPRICGNGTCSN 486
+ C P C+ G+C++T + C+C G+ G++C + +EC +P + G GTC +
Sbjct: 397 NICLSHP--CLNGQCIDTVSGYFCKCDSGWT----GVNCTENINECLSNPCLNG-GTCVD 449
Query: 487 TRGGYECQCSPGFT----QGPDQTC 507
+ C+C+ +T Q P Q C
Sbjct: 450 GVDSFSCECTRLWTGALCQVPQQVC 474
Score = 107 bits (256), Expect = 2e-22
Identities = 96/360 (26%), Positives = 138/360 (38%), Gaps = 49/360 (13%)
Query: 313 RRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEA 371
++ VD+ C P C GG C N + + C CP W+ LC +
Sbjct: 128 QQTVDKKVCSSNP--CQNGGTCLNLHDSFFCICPPQWK------------GPLCSADVNE 173
Query: 372 GRCHRARPLQLARPECCCSEGAAWGRYCE-RCPAPDSAEFMRICQGGMGRPNLTQDLDEC 430
+ PL C + ++ +C P A C+GG + E
Sbjct: 174 CEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGG-SVARCVHGICED 232
Query: 431 RVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGT-CSNTR 488
+R + + C C G++ +P+ +C +D DEC+ P C C NT+
Sbjct: 233 LMREQA--------GEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQ 284
Query: 489 GGYECQCSPGFTQGPDQTCVDVDECAEGRASCT----FRCHNTAGSFRC-TCPYGYAVAA 543
G + C P QG C D++EC C+ C NT GS C CP GY
Sbjct: 285 GSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QG 342
Query: 544 DGVHCRDIDECVQEPRVC-PHA-CENVVGSY-ICKCPEGYRRTSAPQDSENACEDI-NEC 599
DG C D C C P A C + +GS +C C GY N C + N C
Sbjct: 343 DGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGY---GPNGCVQLSNIC 399
Query: 600 EEQEDLCSGGVCINTDGSFLCDCDAGF---EPSEDGTDCIDR---RTGTCYRSLVSGRCE 653
C G CI+T + C CD+G+ +E+ +C+ GTC + S CE
Sbjct: 400 LSHP--CLNGQCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCE 457
Score = 106 bits (254), Expect = 4e-22
Identities = 105/367 (28%), Positives = 150/367 (40%), Gaps = 54/367 (14%)
Query: 106 LCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR---LTPSLDECEDVDECGDQRIC 162
L + VD+ PC+ C+NL +F C CPP ++ + ++ECE G C
Sbjct: 127 LQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYS--GTPLSC 184
Query: 163 DH-GDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPV-CRNGTCENL------PGAY 214
+ G C NT+GSY C C P T D+C C +G CE+L Y
Sbjct: 185 QNGGTCVNTMGSYSCHCPP-ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKY 243
Query: 215 LCHCDDGFKAGPNNDC--VDVNECR-EGGMVCRNGRCRNTVGSFRC-ECAPGYTLTADGR 270
C CD G+ PN+ +D +EC + G +C NT GSF C C G+ +G
Sbjct: 244 SCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGW--QGNGY 301
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYEC-SCGAGWKLVGRRCVDRDECKELPYVC- 328
C D++EC+ C C NT G C +C G++ GR C D C C
Sbjct: 302 ICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCH 361
Query: 329 AGGECRNFNGGY-VCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPEC 387
C + G +C C G+ + + C + + L+ P
Sbjct: 362 PDASCSSTLGSLPLCTCLPGY----------------TGNGYGPNGCVQLSNICLSHP-- 403
Query: 388 CCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTD 446
C G +C S F + G G N T++++EC P C+ GG CV+
Sbjct: 404 -CLNG--------QCIDTVSGYFCKCDSGWTG-VNCTENINECLSNP--CLNGGTCVDGV 451
Query: 447 GSFRCEC 453
SF CEC
Sbjct: 452 DSFSCEC 458
Score = 58.4 bits (135), Expect = 1e-07
Identities = 43/126 (34%), Positives = 54/126 (42%), Gaps = 19/126 (15%)
Query: 747 DVDECAAIPGLCAP--------GRFRC-VCGPGYRPAGEVCADVDECAVRPPPCDQL--- 794
D DEC+ PG C+ G F C C G++ G +C D++EC + C
Sbjct: 263 DRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPV 322
Query: 795 -CHNTDGSYDC-LCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYE-CSCED 849
C NT GS C C GY+ DG C D C C CS+T GS C+C
Sbjct: 323 ECVNTPGSSHCQACPPGYQ--GDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLP 380
Query: 850 GYEKRG 855
GY G
Sbjct: 381 GYTGNG 386
Score = 50.0 bits (114), Expect = 4e-05
Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 9/99 (9%)
Query: 760 PGRFRC-VCGPGYRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYD-CLCRTGYELDED 815
PG C C PGY+ G VC D C+V C D C +T GS C C GY +
Sbjct: 328 PGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGY 387
Query: 816 GAN-CRDVDE-CERDTHTC-QQICSNTEGSYECSCEDGY 851
G N C + C +H C C +T Y C C+ G+
Sbjct: 388 GPNGCVQLSNICL--SHPCLNGQCIDTVSGYFCKCDSGW 424
Score = 44.0 bits (99), Expect = 0.002
Identities = 46/152 (30%), Positives = 61/152 (40%), Gaps = 26/152 (17%)
Query: 501 QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDEC---VQ 556
QG QT VD C+ C N SF C CP + G C D++EC
Sbjct: 125 QGLQQT-VDKKVCSSNPCQNGGTCLNLHDSFFCICPPQW----KGPLCSADVNECEIYSG 179
Query: 557 EPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENACEDINECE-EQEDLCSGGVCIN 613
P C + C N +GSY C CP T PQ ++CE C G+C +
Sbjct: 180 TPLSCQNGGTCVNTMGSYSCHCPP---ETYGPQ----CASKYDDCEGGSVARCVHGICED 232
Query: 614 T------DGSFLCDCDAGFEPSEDGTDC-IDR 638
+ + C CDAG+ S + C +DR
Sbjct: 233 LMREQAGEPKYSCVCDAGWMFSPNSPACTLDR 264
Score = 39.9 bits (89), Expect = 0.038
Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 5/60 (8%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRC 137
C G C DT +G+ C CD G+ N + +++EC PC CV+ +F C C
Sbjct: 404 CLNGQCIDTVSGYFCKCDSGWTGVNCT---ENINECL--SNPCLNGGTCVDGVDSFSCEC 458
Score = 36.7 bits (81), Expect = 0.35
Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 12/75 (16%)
Query: 781 VDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHT---CQQ 834
VD+ PC C N S+ C+C ++ G C DV+ECE + T CQ
Sbjct: 131 VDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWK----GPLCSADVNECEIYSGTPLSCQN 186
Query: 835 --ICSNTEGSYECSC 847
C NT GSY C C
Sbjct: 187 GGTCVNTMGSYSCHC 201
>AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 123 bits (297), Expect = 2e-27
Identities = 115/364 (31%), Positives = 147/364 (40%), Gaps = 68/364 (18%)
Query: 283 HPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECK---ELPYVCA-GGECRNFN 337
+PC G +C N + + C C WK G C D +EC+ P C GG C N
Sbjct: 139 NPCQNGG--TCLNLHDSFFCICPPQWK--GPLCSADVNECEIYSGTPLSCQNGGTCVNTM 194
Query: 338 GGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGR 397
G Y C CP + C + YD+ E G R C G
Sbjct: 195 GSYSCHCPP----ETYGPQCASK-----YDDCEGGSVAR------------CVHGICEDL 233
Query: 398 YCERCPAPDSAEFMRICQGG-MGRPN---LTQDLDECRVRPDVCVG-GRCVNTDGSFRC- 451
E+ P ++ +C G M PN T D DEC +P C +C NT GSF C
Sbjct: 234 MREQAGEP---KYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCG 290
Query: 452 ECPDGYVLAPDGLSCVDADECALDPRICGNGT---CSNTRGGYECQ-CSPGFTQGPDQTC 507
CP G+ +G C D +EC ++ C C NT G CQ C PG+ QG + C
Sbjct: 291 ACPTGW--QGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY-QGDGRVC 347
Query: 508 VDVDECAEGRASC--TFRCHNTAGSFR-CTCPYGYAVAADGVHCRDIDECVQEPRVC-PH 563
D C+ C C +T GS CTC GY G + CVQ +C H
Sbjct: 348 TLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPN-----GCVQLSNICLSH 402
Query: 564 ACEN-----VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSF 618
C N V Y CKC G+ N E+INEC L +GG C++ SF
Sbjct: 403 PCLNGQCIDTVSGYFCKCDSGWTGV-------NCTENINECLSNPCL-NGGTCVDGVDSF 454
Query: 619 LCDC 622
C+C
Sbjct: 455 SCEC 458
Score = 120 bits (290), Expect = 2e-26
Identities = 106/357 (29%), Positives = 151/357 (42%), Gaps = 62/357 (17%)
Query: 243 CRNG-RCRNTVGSFRCECAPGYTLTADGRNCR-DVDECD---ELPHPCGRDGNPSCTNTN 297
C+NG C N SF C C P + G C DV+EC+ P C G +C NT
Sbjct: 141 CQNGGTCLNLHDSFFCICPPQWK----GPLCSADVNECEIYSGTPLSCQNGG--TCVNTM 194
Query: 298 GGYECSCGAGWKLVGRRCVDR-DECKELPYV-CAGGECRNF---NGG---YVCECPAGWR 349
G Y C C + G +C + D+C+ C G C + G Y C C AGW
Sbjct: 195 GSYSCHCPP--ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWM 252
Query: 350 FDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAE 409
F + C +R E C ++ G C +C ++G+ YC CP
Sbjct: 253 FSPNSPACTLDRDE-C--SFQPGPCS-------TLVQCFNTQGSF---YCGACPT----- 294
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVGG---RCVNTDGSFRCE-CPDGYVLAPDGLS 465
G G + +D++EC + C CVNT GS C+ CP GY DG
Sbjct: 295 ------GWQGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QGDGRV 346
Query: 466 CVDADECALDPRIC-GNGTCSNTRGGYE-CQCSPGFT---QGPDQTCVDVDECAEGRASC 520
C D C++ C + +CS+T G C C PG+T GP+ CV +
Sbjct: 347 CTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPN-GCVQLSNICLSHPCL 405
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVCPHACENVVGSYICKC 576
+C +T + C C G+ GV+C +I+EC+ P + C + V S+ C+C
Sbjct: 406 NGQCIDTVSGYFCKCDSGWT----GVNCTENINECLSNPCLNGGTCVDGVDSFSCEC 458
Score = 119 bits (286), Expect = 5e-26
Identities = 91/275 (33%), Positives = 127/275 (46%), Gaps = 31/275 (11%)
Query: 90 FQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFEC-RCPPGYRLTPSL 147
+ C CD G+ S C D DECS+ PC + QC N G+F C CP G++ +
Sbjct: 243 YSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYI 302
Query: 148 DECEDVDEC----GDQRICDHGDCRNTIGSYRCE-CKPGYTLRENVCRDVDECSRPRPVC 202
CED++EC G + +C NT GS C+ C PGY VC D CS C
Sbjct: 303 --CEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGC 360
Query: 203 R-NGTCENLPGAY-LCHCDDGFKA---GPNNDCVDV-NECREGGMVCRNGRCRNTVGSFR 256
+ +C + G+ LC C G+ GPN CV + N C C NG+C +TV +
Sbjct: 361 HPDASCSSTLGSLPLCTCLPGYTGNGYGPNG-CVQLSNICL--SHPCLNGQCIDTVSGYF 417
Query: 257 CECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
C+C G+T G NC +++EC L +PC G +C + + C C W G C
Sbjct: 418 CKCDSGWT----GVNCTENINEC--LSNPCLNGG--TCVDGVDSFSCECTRLW--TGALC 467
Query: 316 -VDRDECKE-LPYVCAGGECRNFNGGYVCECPAGW 348
V + C E L + R+ + GYV + W
Sbjct: 468 QVPQQVCGESLSGINGSFSYRSPDVGYVHDVNCFW 502
Score = 114 bits (275), Expect = 1e-24
Identities = 111/385 (28%), Positives = 157/385 (40%), Gaps = 61/385 (15%)
Query: 147 LDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECS--RPRPV-C 202
L + D C + G C N S+ C C P + + +C DV+EC P+ C
Sbjct: 127 LQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQW--KGPLCSADVNECEIYSGTPLSC 184
Query: 203 RNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMV--CRNGRC----RNTVGS- 254
+NG TC N G+Y CHC GP C + EGG V C +G C R G
Sbjct: 185 QNGGTCVNTMGSYSCHCPPE-TYGPQ--CASKYDDCEGGSVARCVHGICEDLMREQAGEP 241
Query: 255 -FRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYEC-SCGAGWKLV 311
+ C C G+ + + C D DEC P PC C NT G + C +C GW+
Sbjct: 242 KYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCST--LVQCFNTQGSFYCGACPTGWQGN 299
Query: 312 GRRCVDRDECKELPYVCAGG---ECRNFNGGYVCE-CPAGWRFDKTAAVCVDERKELCYD 367
G C D +EC+ C+ EC N G C+ CP G++ D D +C
Sbjct: 300 GYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTD----IC-- 353
Query: 368 EWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDL 427
G CH P+ CS C P G G Q
Sbjct: 354 SVSNGGCH---------PDASCSSTLGSLPLCTCLPGYTG--------NGYGPNGCVQLS 396
Query: 428 DECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVD-ADECALDPRICGNGTCSN 486
+ C P C+ G+C++T + C+C G+ G++C + +EC +P + G GTC +
Sbjct: 397 NICLSHP--CLNGQCIDTVSGYFCKCDSGWT----GVNCTENINECLSNPCLNG-GTCVD 449
Query: 487 TRGGYECQCSPGFT----QGPDQTC 507
+ C+C+ +T Q P Q C
Sbjct: 450 GVDSFSCECTRLWTGALCQVPQQVC 474
Score = 107 bits (256), Expect = 2e-22
Identities = 96/360 (26%), Positives = 138/360 (38%), Gaps = 49/360 (13%)
Query: 313 RRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEA 371
++ VD+ C P C GG C N + + C CP W+ LC +
Sbjct: 128 QQTVDKKVCSSNP--CQNGGTCLNLHDSFFCICPPQWK------------GPLCSADVNE 173
Query: 372 GRCHRARPLQLARPECCCSEGAAWGRYCE-RCPAPDSAEFMRICQGGMGRPNLTQDLDEC 430
+ PL C + ++ +C P A C+GG + E
Sbjct: 174 CEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGG-SVARCVHGICED 232
Query: 431 RVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNGT-CSNTR 488
+R + + C C G++ +P+ +C +D DEC+ P C C NT+
Sbjct: 233 LMREQA--------GEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQ 284
Query: 489 GGYECQCSPGFTQGPDQTCVDVDECAEGRASCT----FRCHNTAGSFRC-TCPYGYAVAA 543
G + C P QG C D++EC C+ C NT GS C CP GY
Sbjct: 285 GSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QG 342
Query: 544 DGVHCRDIDECVQEPRVC-PHA-CENVVGSY-ICKCPEGYRRTSAPQDSENACEDI-NEC 599
DG C D C C P A C + +GS +C C GY N C + N C
Sbjct: 343 DGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGY---GPNGCVQLSNIC 399
Query: 600 EEQEDLCSGGVCINTDGSFLCDCDAGF---EPSEDGTDCIDR---RTGTCYRSLVSGRCE 653
C G CI+T + C CD+G+ +E+ +C+ GTC + S CE
Sbjct: 400 LSHP--CLNGQCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCE 457
Score = 106 bits (254), Expect = 4e-22
Identities = 105/367 (28%), Positives = 150/367 (40%), Gaps = 54/367 (14%)
Query: 106 LCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR---LTPSLDECEDVDECGDQRIC 162
L + VD+ PC+ C+NL +F C CPP ++ + ++ECE G C
Sbjct: 127 LQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYS--GTPLSC 184
Query: 163 DH-GDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPV-CRNGTCENL------PGAY 214
+ G C NT+GSY C C P T D+C C +G CE+L Y
Sbjct: 185 QNGGTCVNTMGSYSCHCPP-ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKY 243
Query: 215 LCHCDDGFKAGPNNDC--VDVNECR-EGGMVCRNGRCRNTVGSFRC-ECAPGYTLTADGR 270
C CD G+ PN+ +D +EC + G +C NT GSF C C G+ +G
Sbjct: 244 SCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGW--QGNGY 301
Query: 271 NCRDVDECDELPHPCGRDGNPSCTNTNGGYEC-SCGAGWKLVGRRCVDRDECKELPYVC- 328
C D++EC+ C C NT G C +C G++ GR C D C C
Sbjct: 302 ICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCH 361
Query: 329 AGGECRNFNGGY-VCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPEC 387
C + G +C C G+ + + C + + L+ P
Sbjct: 362 PDASCSSTLGSLPLCTCLPGY----------------TGNGYGPNGCVQLSNICLSHP-- 403
Query: 388 CCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTD 446
C G +C S F + G G N T++++EC P C+ GG CV+
Sbjct: 404 -CLNG--------QCIDTVSGYFCKCDSGWTG-VNCTENINECLSNP--CLNGGTCVDGV 451
Query: 447 GSFRCEC 453
SF CEC
Sbjct: 452 DSFSCEC 458
Score = 58.4 bits (135), Expect = 1e-07
Identities = 43/126 (34%), Positives = 54/126 (42%), Gaps = 19/126 (15%)
Query: 747 DVDECAAIPGLCAP--------GRFRC-VCGPGYRPAGEVCADVDECAVRPPPCDQL--- 794
D DEC+ PG C+ G F C C G++ G +C D++EC + C
Sbjct: 263 DRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPV 322
Query: 795 -CHNTDGSYDC-LCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYE-CSCED 849
C NT GS C C GY+ DG C D C C CS+T GS C+C
Sbjct: 323 ECVNTPGSSHCQACPPGYQ--GDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLP 380
Query: 850 GYEKRG 855
GY G
Sbjct: 381 GYTGNG 386
Score = 50.0 bits (114), Expect = 4e-05
Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 9/99 (9%)
Query: 760 PGRFRC-VCGPGYRPAGEVCADVDECAVRPPPC--DQLCHNTDGSYD-CLCRTGYELDED 815
PG C C PGY+ G VC D C+V C D C +T GS C C GY +
Sbjct: 328 PGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGY 387
Query: 816 GAN-CRDVDE-CERDTHTC-QQICSNTEGSYECSCEDGY 851
G N C + C +H C C +T Y C C+ G+
Sbjct: 388 GPNGCVQLSNICL--SHPCLNGQCIDTVSGYFCKCDSGW 424
Score = 44.0 bits (99), Expect = 0.002
Identities = 46/152 (30%), Positives = 61/152 (40%), Gaps = 26/152 (17%)
Query: 501 QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHC-RDIDEC---VQ 556
QG QT VD C+ C N SF C CP + G C D++EC
Sbjct: 125 QGLQQT-VDKKVCSSNPCQNGGTCLNLHDSFFCICPPQW----KGPLCSADVNECEIYSG 179
Query: 557 EPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENACEDINECE-EQEDLCSGGVCIN 613
P C + C N +GSY C CP T PQ ++CE C G+C +
Sbjct: 180 TPLSCQNGGTCVNTMGSYSCHCPP---ETYGPQ----CASKYDDCEGGSVARCVHGICED 232
Query: 614 T------DGSFLCDCDAGFEPSEDGTDC-IDR 638
+ + C CDAG+ S + C +DR
Sbjct: 233 LMREQAGEPKYSCVCDAGWMFSPNSPACTLDR 264
Score = 39.9 bits (89), Expect = 0.038
Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 5/60 (8%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRC 137
C G C DT +G+ C CD G+ N + +++EC PC CV+ +F C C
Sbjct: 404 CLNGQCIDTVSGYFCKCDSGWTGVNCT---ENINECL--SNPCLNGGTCVDGVDSFSCEC 458
Score = 36.7 bits (81), Expect = 0.35
Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 12/75 (16%)
Query: 781 VDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHT---CQQ 834
VD+ PC C N S+ C+C ++ G C DV+ECE + T CQ
Sbjct: 131 VDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWK----GPLCSADVNECEIYSGTPLSCQN 186
Query: 835 --ICSNTEGSYECSC 847
C NT GSY C C
Sbjct: 187 GGTCVNTMGSYSCHC 201
>X12892-1|CAA31383.1| 650|Homo sapiens protein ( H.sapiens mRNA for
protein S. ).
Length = 650
Score = 123 bits (296), Expect = 3e-27
Identities = 65/184 (35%), Positives = 104/184 (56%), Gaps = 18/184 (9%)
Query: 461 PDGLSCVDA--DECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEG- 516
PD SCV+A D+C+ P G +C + + + C C PG+ QG ++ D++EC +
Sbjct: 82 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGW-QG-EKCEFDINECKDPS 139
Query: 517 --RASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYI 573
C+ C NT GS+ C+C G+ + ++ C+D+DEC +P +C A C+N++G +
Sbjct: 140 NINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFE 199
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDA--GFEPSED 631
C+CPEGYR +CEDI+EC E++C+ +C+N G C CD GF+ ++D
Sbjct: 200 CECPEGYRYNL----KSKSCEDIDEC--SENMCA-QLCVNYPGGHTCYCDGKKGFKLAQD 252
Query: 632 GTDC 635
C
Sbjct: 253 QKSC 256
Score = 108 bits (259), Expect = 9e-23
Identities = 62/177 (35%), Positives = 86/177 (48%), Gaps = 20/177 (11%)
Query: 145 PSLDECEDV--DECGDQRICDHG--DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRP 200
P L C + D+C + G C++ S+ C CKPG+ E D++EC P
Sbjct: 82 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ-GEKCEFDINECKDPSN 140
Query: 201 VCRNG----TCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSF 255
+ NG C+N PG+Y C C +GF N DC DV+EC +C C+N +G F
Sbjct: 141 I--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDF 198
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA--GWKL 310
CEC GY ++C D+DEC E + C + C N GG+ C C G+KL
Sbjct: 199 ECECPEGYRYNLKSKSCEDIDECSE--NMCAQ----LCVNYPGGHTCYCDGKKGFKL 249
Score = 104 bits (249), Expect = 2e-21
Identities = 61/179 (34%), Positives = 88/179 (49%), Gaps = 20/179 (11%)
Query: 111 DECSWGRPPCR--GMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG-- 165
D+CS PC G C + +F C C PG++ ++CE D++EC D + G
Sbjct: 93 DQCS--PLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCS 146
Query: 166 -DCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
C NT GSY C CK G+ + N C+DVDECS +C C+N+ G + C C +G+
Sbjct: 147 QICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGY 206
Query: 223 KAG-PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCEC--APGYTLTADGRNCRDVDEC 278
+ + C D++EC E +C C N G C C G+ L D ++C V C
Sbjct: 207 RYNLKSKSCEDIDECSEN--MCAQ-LCVNYPGGHTCYCDGKKGFKLAQDQKSCEVVSVC 262
Score = 103 bits (248), Expect = 2e-21
Identities = 51/153 (33%), Positives = 74/153 (48%), Gaps = 7/153 (4%)
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR--CVNTDGSFRCECPDGYVLAPDGLS 465
A F C+ G D++EC+ ++ G C NT GS+ C C +G+V+ +
Sbjct: 113 ASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKD 172
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG-PDQTCVDVDECAEGRASCTFRC 524
C D DEC+L P ICG C N G +EC+C G+ ++C D+DEC+E C C
Sbjct: 173 CKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKSKSCEDIDECSEN--MCAQLC 230
Query: 525 HNTAGSFRCTC--PYGYAVAADGVHCRDIDECV 555
N G C C G+ +A D C + C+
Sbjct: 231 VNYPGGHTCYCDGKKGFKLAQDQKSCEVVSVCL 263
Score = 97.1 bits (231), Expect = 2e-19
Identities = 59/170 (34%), Positives = 87/170 (51%), Gaps = 21/170 (12%)
Query: 184 LRENVCRDVDECSRPRPVCRNG--TCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGG 240
LR V D+CS P P +G +C++ ++ C C G++ C D+NEC++
Sbjct: 84 LRSCVNAIPDQCS-PLPCNEDGYMSCKDGKASFTCTCKPGWQG---EKCEFDINECKDPS 139
Query: 241 MVCRNGRCR----NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
+ NG C NT GS+ C C G+ + ++ ++C+DVDEC P CG C N
Sbjct: 140 NI--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG---TAVCKNI 194
Query: 297 NGGYECSCGAGWK--LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
G +EC C G++ L + C D DEC E +CA C N+ GG+ C C
Sbjct: 195 LGDFECECPEGYRYNLKSKSCEDIDECSE--NMCA-QLCVNYPGGHTCYC 241
Score = 87.0 bits (206), Expect = 3e-16
Identities = 45/117 (38%), Positives = 60/117 (51%), Gaps = 7/117 (5%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
C +TP + C C +G+ + C+DVDECS +P G A C N+ G FEC CP GYR
Sbjct: 149 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSL-KPSICGTAVCKNILGDFECECPEGYR 207
Query: 143 LTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCEC--KPGYTLREN--VCRDVDEC 195
CED+DEC + +C C N G + C C K G+ L ++ C V C
Sbjct: 208 YNLKSKSCEDIDEC-SENMCAQ-LCVNYPGGHTCYCDGKKGFKLAQDQKSCEVVSVC 262
Score = 86.6 bits (205), Expect = 3e-16
Identities = 45/128 (35%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Query: 236 CREGG-MVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSC 293
C E G M C++G+ SF C C PG+ G C D++EC + P + C
Sbjct: 100 CNEDGYMSCKDGKA-----SFTCTCKPGW----QGEKCEFDINECKD-PSNINGGCSQIC 149
Query: 294 TNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFD 351
NT G Y CSC G+ ++ + C D DEC P +C C+N G + CECP G+R++
Sbjct: 150 DNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYN 209
Query: 352 KTAAVCVD 359
+ C D
Sbjct: 210 LKSKSCED 217
Score = 82.6 bits (195), Expect = 5e-15
Identities = 44/118 (37%), Positives = 63/118 (53%), Gaps = 19/118 (16%)
Query: 749 DECAAIP----GL--CAPGR--FRCVCGPGYRPAGEVCA-DVDECAVRPPP-----CDQL 794
D+C+ +P G C G+ F C C PG++ GE C D++EC + P C Q+
Sbjct: 93 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ--GEKCEFDINEC--KDPSNINGGCSQI 148
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGY 851
C NT GSY C C+ G+ + + +C+DVDEC C +C N G +EC C +GY
Sbjct: 149 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGY 206
Score = 74.5 bits (175), Expect = 1e-12
Identities = 39/118 (33%), Positives = 54/118 (45%), Gaps = 12/118 (10%)
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRV---CPHACENVVGSYICKCPEG 579
C + SF CTC G+ G C DI+EC + C C+N GSY C C G
Sbjct: 108 CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNG 163
Query: 580 YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
+ S +D C+D++EC + +C VC N G F C+C G+ + C D
Sbjct: 164 FVMLSNKKD----CKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKSKSCED 217
Score = 74.1 bits (174), Expect = 2e-12
Identities = 38/114 (33%), Positives = 57/114 (50%), Gaps = 14/114 (12%)
Query: 747 DVDEC---AAIPGLCA------PGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQ-L 794
D++EC + I G C+ PG + C C G+ C DVDEC+++P C +
Sbjct: 131 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAV 190
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCE 848
C N G ++C C GY + +C D+DEC + C Q+C N G + C C+
Sbjct: 191 CKNILGDFECECPEGYRYNLKSKSCEDIDECSE--NMCAQLCVNYPGGHTCYCD 242
Score = 72.1 bits (169), Expect = 8e-12
Identities = 47/157 (29%), Positives = 64/157 (40%), Gaps = 24/157 (15%)
Query: 18 QTKYLCCCSVGHAW-GAPCE----AC--PPRGSPAHTALCGEKPGEYINPVTN------- 63
+ + C C G W G CE C P + + +C PG Y N
Sbjct: 112 KASFTCTCKPG--WQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSN 169
Query: 64 --ETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
+ K +DEC + P +C C + F+C C GY ++ S C D+DECS C
Sbjct: 170 KKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKSKSCEDIDECS--ENMCA 227
Query: 122 GMAQCVNLPGAFECRC--PPGYRLTPSLDECEDVDEC 156
+ CVN PG C C G++L CE V C
Sbjct: 228 QL--CVNYPGGHTCYCDGKKGFKLAQDQKSCEVVSVC 262
>M14338-1|AAA60181.1| 650|Homo sapiens protein S precursor protein.
Length = 650
Score = 123 bits (296), Expect = 3e-27
Identities = 65/184 (35%), Positives = 104/184 (56%), Gaps = 18/184 (9%)
Query: 461 PDGLSCVDA--DECALDP-RICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEG- 516
PD SCV+A D+C+ P G +C + + + C C PG+ QG ++ D++EC +
Sbjct: 82 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGW-QG-EKCEFDINECKDPS 139
Query: 517 --RASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYI 573
C+ C NT GS+ C+C G+ + ++ C+D+DEC +P +C A C+N++G +
Sbjct: 140 NINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFE 199
Query: 574 CKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDA--GFEPSED 631
C+CPEGYR +CEDI+EC E++C+ +C+N G C CD GF+ ++D
Sbjct: 200 CECPEGYRYNL----KSKSCEDIDEC--SENMCA-QLCVNYPGGHTCYCDGKKGFKLAQD 252
Query: 632 GTDC 635
C
Sbjct: 253 QKSC 256
Score = 108 bits (259), Expect = 9e-23
Identities = 62/177 (35%), Positives = 86/177 (48%), Gaps = 20/177 (11%)
Query: 145 PSLDECEDV--DECGDQRICDHG--DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRP 200
P L C + D+C + G C++ S+ C CKPG+ E D++EC P
Sbjct: 82 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ-GEKCEFDINECKDPSN 140
Query: 201 VCRNG----TCENLPGAYLCHCDDGFKAGPNN-DCVDVNECREGGMVCRNGRCRNTVGSF 255
+ NG C+N PG+Y C C +GF N DC DV+EC +C C+N +G F
Sbjct: 141 I--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDF 198
Query: 256 RCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA--GWKL 310
CEC GY ++C D+DEC E + C + C N GG+ C C G+KL
Sbjct: 199 ECECPEGYRYNLKSKSCEDIDECSE--NMCAQ----LCVNYPGGHTCYCDGKKGFKL 249
Score = 104 bits (249), Expect = 2e-21
Identities = 61/179 (34%), Positives = 88/179 (49%), Gaps = 20/179 (11%)
Query: 111 DECSWGRPPCR--GMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG-- 165
D+CS PC G C + +F C C PG++ ++CE D++EC D + G
Sbjct: 93 DQCS--PLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCS 146
Query: 166 -DCRNTIGSYRCECKPGYTLRENV--CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
C NT GSY C CK G+ + N C+DVDECS +C C+N+ G + C C +G+
Sbjct: 147 QICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGY 206
Query: 223 KAG-PNNDCVDVNECREGGMVCRNGRCRNTVGSFRCEC--APGYTLTADGRNCRDVDEC 278
+ + C D++EC E +C C N G C C G+ L D ++C V C
Sbjct: 207 RYNLKSKSCEDIDECSEN--MCAQ-LCVNYPGGHTCYCDGKKGFKLAQDQKSCEVVSVC 262
Score = 103 bits (248), Expect = 2e-21
Identities = 51/153 (33%), Positives = 74/153 (48%), Gaps = 7/153 (4%)
Query: 408 AEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR--CVNTDGSFRCECPDGYVLAPDGLS 465
A F C+ G D++EC+ ++ G C NT GS+ C C +G+V+ +
Sbjct: 113 ASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKD 172
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQG-PDQTCVDVDECAEGRASCTFRC 524
C D DEC+L P ICG C N G +EC+C G+ ++C D+DEC+E C C
Sbjct: 173 CKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKSKSCEDIDECSEN--MCAQLC 230
Query: 525 HNTAGSFRCTC--PYGYAVAADGVHCRDIDECV 555
N G C C G+ +A D C + C+
Sbjct: 231 VNYPGGHTCYCDGKKGFKLAQDQKSCEVVSVCL 263
Score = 97.1 bits (231), Expect = 2e-19
Identities = 59/170 (34%), Positives = 87/170 (51%), Gaps = 21/170 (12%)
Query: 184 LRENVCRDVDECSRPRPVCRNG--TCENLPGAYLCHCDDGFKAGPNNDC-VDVNECREGG 240
LR V D+CS P P +G +C++ ++ C C G++ C D+NEC++
Sbjct: 84 LRSCVNAIPDQCS-PLPCNEDGYMSCKDGKASFTCTCKPGWQG---EKCEFDINECKDPS 139
Query: 241 MVCRNGRCR----NTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNT 296
+ NG C NT GS+ C C G+ + ++ ++C+DVDEC P CG C N
Sbjct: 140 NI--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG---TAVCKNI 194
Query: 297 NGGYECSCGAGWK--LVGRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
G +EC C G++ L + C D DEC E +CA C N+ GG+ C C
Sbjct: 195 LGDFECECPEGYRYNLKSKSCEDIDECSE--NMCA-QLCVNYPGGHTCYC 241
Score = 87.0 bits (206), Expect = 3e-16
Identities = 45/117 (38%), Positives = 60/117 (51%), Gaps = 7/117 (5%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYR 142
C +TP + C C +G+ + C+DVDECS +P G A C N+ G FEC CP GYR
Sbjct: 149 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSL-KPSICGTAVCKNILGDFECECPEGYR 207
Query: 143 LTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCEC--KPGYTLREN--VCRDVDEC 195
CED+DEC + +C C N G + C C K G+ L ++ C V C
Sbjct: 208 YNLKSKSCEDIDEC-SENMCAQ-LCVNYPGGHTCYCDGKKGFKLAQDQKSCEVVSVC 262
Score = 86.6 bits (205), Expect = 3e-16
Identities = 45/128 (35%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Query: 236 CREGG-MVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSC 293
C E G M C++G+ SF C C PG+ G C D++EC + P + C
Sbjct: 100 CNEDGYMSCKDGKA-----SFTCTCKPGW----QGEKCEFDINECKD-PSNINGGCSQIC 149
Query: 294 TNTNGGYECSCGAGWKLVGRR--CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFD 351
NT G Y CSC G+ ++ + C D DEC P +C C+N G + CECP G+R++
Sbjct: 150 DNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYN 209
Query: 352 KTAAVCVD 359
+ C D
Sbjct: 210 LKSKSCED 217
Score = 82.6 bits (195), Expect = 5e-15
Identities = 44/118 (37%), Positives = 63/118 (53%), Gaps = 19/118 (16%)
Query: 749 DECAAIP----GL--CAPGR--FRCVCGPGYRPAGEVCA-DVDECAVRPPP-----CDQL 794
D+C+ +P G C G+ F C C PG++ GE C D++EC + P C Q+
Sbjct: 93 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ--GEKCEFDINEC--KDPSNINGGCSQI 148
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGY 851
C NT GSY C C+ G+ + + +C+DVDEC C +C N G +EC C +GY
Sbjct: 149 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGY 206
Score = 74.5 bits (175), Expect = 1e-12
Identities = 39/118 (33%), Positives = 54/118 (45%), Gaps = 12/118 (10%)
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRV---CPHACENVVGSYICKCPEG 579
C + SF CTC G+ G C DI+EC + C C+N GSY C C G
Sbjct: 108 CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNG 163
Query: 580 YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
+ S +D C+D++EC + +C VC N G F C+C G+ + C D
Sbjct: 164 FVMLSNKKD----CKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKSKSCED 217
Score = 74.1 bits (174), Expect = 2e-12
Identities = 38/114 (33%), Positives = 57/114 (50%), Gaps = 14/114 (12%)
Query: 747 DVDEC---AAIPGLCA------PGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQ-L 794
D++EC + I G C+ PG + C C G+ C DVDEC+++P C +
Sbjct: 131 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAV 190
Query: 795 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCE 848
C N G ++C C GY + +C D+DEC + C Q+C N G + C C+
Sbjct: 191 CKNILGDFECECPEGYRYNLKSKSCEDIDECSE--NMCAQLCVNYPGGHTCYCD 242
Score = 72.1 bits (169), Expect = 8e-12
Identities = 47/157 (29%), Positives = 64/157 (40%), Gaps = 24/157 (15%)
Query: 18 QTKYLCCCSVGHAW-GAPCE----AC--PPRGSPAHTALCGEKPGEYINPVTN------- 63
+ + C C G W G CE C P + + +C PG Y N
Sbjct: 112 KASFTCTCKPG--WQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSN 169
Query: 64 --ETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
+ K +DEC + P +C C + F+C C GY ++ S C D+DECS C
Sbjct: 170 KKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKSKSCEDIDECS--ENMCA 227
Query: 122 GMAQCVNLPGAFECRC--PPGYRLTPSLDECEDVDEC 156
+ CVN PG C C G++L CE V C
Sbjct: 228 QL--CVNYPGGHTCYCDGKKGFKLAQDQKSCEVVSVC 262
>AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein
protein.
Length = 3574
Score = 122 bits (293), Expect = 7e-27
Identities = 82/241 (34%), Positives = 114/241 (47%), Gaps = 34/241 (14%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
GTC G+ C C GY T C D+DECS PC C +L G F C CP
Sbjct: 1206 GTCQQLGRGYVCLCPLGY----TGLKCETDIDECS--PLPCLNNGVCKDLVGEFICECPS 1259
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPR 199
GY T E E+++EC + G C + + YRC C G+ + + +V+EC +
Sbjct: 1260 GY--TGQRCE-ENINECSSSPCLNKGICVDGVAGYRCTCVKGF-VGLHCETEVNEC-QSN 1314
Query: 200 PVCRNGTCENLPGAYLCHCDDGF---KAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSF 255
P N CE+ G +LC C GF + G N V+EC C+NG C++ SF
Sbjct: 1315 PCLNNAVCEDQVGGFLCKCPPGFLGTRCGKN-----VDECL--SQPCKNGATCKDGANSF 1367
Query: 256 RCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR 314
RC CA G+T G +C +++EC +PC +C + Y C C G+ G+R
Sbjct: 1368 RCLCAAGFT----GSHCELNINECQS--NPCRNQA--TCVDELNSYSCKCQPGFS--GKR 1417
Query: 315 C 315
C
Sbjct: 1418 C 1418
Score = 117 bits (281), Expect = 2e-25
Identities = 76/233 (32%), Positives = 112/233 (48%), Gaps = 23/233 (9%)
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCE 177
PC C L + C CP GY +CE D+DEC ++G C++ +G + CE
Sbjct: 1201 PCHNSGTCQQLGRGYVCLCPLGYTGL----KCETDIDECSPLPCLNNGVCKDLVGEFICE 1256
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECR 237
C GYT + +++ECS P G C + Y C C GF G + + +VNEC+
Sbjct: 1257 CPSGYT-GQRCEENINECS-SSPCLNKGICVDGVAGYRCTCVKGF-VGLHCE-TEVNECQ 1312
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTN 297
+ N C + VG F C+C PG+ T G+N VDEC L PC ++G +C +
Sbjct: 1313 SNPCL-NNAVCEDQVGGFLCKCPPGFLGTRCGKN---VDEC--LSQPC-KNG-ATCKDGA 1364
Query: 298 GGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECRNFNGGYVCECPAGW 348
+ C C AG+ G C ++ +EC+ P C C + Y C+C G+
Sbjct: 1365 NSFRCLCAAGF--TGSHCELNINECQSNP--CRNQATCVDELNSYSCKCQPGF 1413
Score = 101 bits (241), Expect = 1e-20
Identities = 67/202 (33%), Positives = 103/202 (50%), Gaps = 24/202 (11%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD-VDECSWGRPPCRGMAQC 126
IDEC +P L G C D F C C GY T C + ++ECS PC C
Sbjct: 1232 IDECSPLPCL-NNGVCKDLVGEFICECPSGY----TGQRCEENINECS--SSPCLNKGIC 1284
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
V+ + C C G+ L CE +V+EC ++ C + +G + C+C PG+ L
Sbjct: 1285 VDGVAGYRCTCVKGF---VGL-HCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGF-LG 1339
Query: 186 ENVCRDVDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC 243
++VDEC S+P C+NG TC++ ++ C C GF G + + +++NEC+ C
Sbjct: 1340 TRCGKNVDECLSQP---CKNGATCKDGANSFRCLCAAGF-TGSHCE-LNINECQSNP--C 1392
Query: 244 RN-GRCRNTVGSFRCECAPGYT 264
RN C + + S+ C+C PG++
Sbjct: 1393 RNQATCVDELNSYSCKCQPGFS 1414
Score = 99 bits (238), Expect = 3e-20
Identities = 74/240 (30%), Positives = 107/240 (44%), Gaps = 32/240 (13%)
Query: 424 TQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGN 481
+Q EC P C G C + C CP GY GL C D DEC+ P + N
Sbjct: 1191 SQVFHECFFNP--CHNSGTCQQLGRGYVCLCPLGYT----GLKCETDIDECSPLPCL-NN 1243
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHNTAGSFRCTCPYGYA 540
G C + G + C+C G+T Q C + ++EC+ C + +RCTC G+
Sbjct: 1244 GVCKDLVGEFICECPSGYT---GQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFV 1300
Query: 541 VAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINEC 599
G+HC +++EC P + CE+ VG ++CKCP G+ T ++++EC
Sbjct: 1301 ----GLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGT-------RCGKNVDEC 1349
Query: 600 EEQEDLCSGGVCINTDGSFLCDCDAGFEPSE---DGTDCID---RRTGTCYRSLVSGRCE 653
Q +G C + SF C C AGF S + +C R TC L S C+
Sbjct: 1350 LSQ-PCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCK 1408
Score = 96.7 bits (230), Expect = 3e-19
Identities = 77/252 (30%), Positives = 113/252 (44%), Gaps = 34/252 (13%)
Query: 155 ECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGTCENLPGA 213
EC + G C+ Y C C GYT + C D+DECS P P NG C++L G
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLK--CETDIDECS-PLPCLNNGVCKDLVGE 1252
Query: 214 YLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR 273
++C C G+ + ++NEC + G C + V +RC C G+ G +C
Sbjct: 1253 FICECPSGYTGQRCEE--NINECSSSPCL-NKGICVDGVAGYRCTCVKGFV----GLHCE 1305
Query: 274 -DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCA-G 330
+V+EC +PC N C + GG+ C C G+ +G RC + DEC P C G
Sbjct: 1306 TEVNECQS--NPC--LNNAVCEDQVGGFLCKCPPGF--LGTRCGKNVDECLSQP--CKNG 1357
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPL--QLARPECC 388
C++ + C C AG+ T + C EL +E ++ C +L C
Sbjct: 1358 ATCKDGANSFRCLCAAGF----TGSHC-----ELNINECQSNPCRNQATCVDELNSYSCK 1408
Query: 389 CSEGAAWGRYCE 400
C G + G+ CE
Sbjct: 1409 CQPGFS-GKRCE 1419
Score = 96.7 bits (230), Expect = 3e-19
Identities = 67/222 (30%), Positives = 99/222 (44%), Gaps = 28/222 (12%)
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
++ +C G D+DEC P C+ G C + G F CECP GY G C +
Sbjct: 1215 YVCLCPLGYTGLKCETDIDECSPLP--CLNNGVCKDLVGEFICECPSGYT----GQRCEE 1268
Query: 469 -ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNT 527
+EC+ P + G C + GY C C GF +T +V+EC C +
Sbjct: 1269 NINECSSSPCL-NKGICVDGVAGYRCTCVKGFVGLHCET--EVNECQSNPCLNNAVCEDQ 1325
Query: 528 AGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAP 586
G F C CP G+ G C +++DEC+ +P C++ S+ C C G+
Sbjct: 1326 VGGFLCKCPPGFL----GTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGF------ 1375
Query: 587 QDSENACE-DINECEEQEDLCSG-GVCINTDGSFLCDCDAGF 626
+ + CE +INEC Q + C C++ S+ C C GF
Sbjct: 1376 --TGSHCELNINEC--QSNPCRNQATCVDELNSYSCKCQPGF 1413
Score = 92.7 bits (220), Expect = 5e-18
Identities = 57/175 (32%), Positives = 82/175 (46%), Gaps = 16/175 (9%)
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSC- 466
EF+ C G ++++EC P C+ G CV+ +RC C G+V GL C
Sbjct: 1252 EFICECPSGYTGQRCEENINECSSSP--CLNKGICVDGVAGYRCTCVKGFV----GLHCE 1305
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHN 526
+ +EC +P + N C + GG+ C+C PGF + +VDEC C +
Sbjct: 1306 TEVNECQSNPCL-NNAVCEDQVGGFLCKCPPGFLG--TRCGKNVDECLSQPCKNGATCKD 1362
Query: 527 TAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGY 580
A SFRC C G+ G HC +I+EC P C + + SY CKC G+
Sbjct: 1363 GANSFRCLCAAGFT----GSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGF 1413
Score = 82.2 bits (194), Expect = 7e-15
Identities = 68/232 (29%), Positives = 97/232 (41%), Gaps = 31/232 (13%)
Query: 283 HPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYV 341
+PC G +C GY C C G+ G +C D DEC LP + G C++ G ++
Sbjct: 1200 NPCHNSG--TCQQLGRGYVCLCPLGY--TGLKCETDIDECSPLPCL-NNGVCKDLVGEFI 1254
Query: 342 CECPAGW---RFDKTAAVCVDE---RKELCYDEWEAGRCHRARPLQLARPEC----CCSE 391
CECP+G+ R ++ C K +C D RC + E C S
Sbjct: 1255 CECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN 1314
Query: 392 GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFR 450
CE F+ C G +++DEC +P C G C + SFR
Sbjct: 1315 PCLNNAVCE----DQVGGFLCKCPPGFLGTRCGKNVDECLSQP--CKNGATCKDGANSFR 1368
Query: 451 CECPDGYVLAPDGLSC-VDADECALDPRICGN-GTCSNTRGGYECQCSPGFT 500
C C G+ G C ++ +EC +P C N TC + Y C+C PGF+
Sbjct: 1369 CLCAAGFT----GSHCELNINECQSNP--CRNQATCVDELNSYSCKCQPGFS 1414
Score = 61.7 bits (143), Expect = 1e-08
Identities = 56/220 (25%), Positives = 87/220 (39%), Gaps = 21/220 (9%)
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKEL-------CYDEWEAGRCHRARPLQLA 383
G C+ GYVC CP G+ K +DE L C D C
Sbjct: 1206 GTCQQLGRGYVCLCPLGYTGLK-CETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQ 1264
Query: 384 RPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-C 442
R E +E ++ + A + C G + +++EC+ P C+ C
Sbjct: 1265 RCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNP--CLNNAVC 1322
Query: 443 VNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNG-TCSNTRGGYECQCSPGFT 500
+ G F C+CP G++ G C + DEC P C NG TC + + C C+ GFT
Sbjct: 1323 EDQVGGFLCKCPPGFL----GTRCGKNVDECLSQP--CKNGATCKDGANSFRCLCAAGFT 1376
Query: 501 QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA 540
+ ++++EC C + S+ C C G++
Sbjct: 1377 GSHCE--LNINECQSNPCRNQATCVDELNSYSCKCQPGFS 1414
Score = 60.9 bits (141), Expect = 2e-08
Identities = 38/135 (28%), Positives = 54/135 (40%), Gaps = 6/135 (4%)
Query: 202 CRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAP 261
C NG C D+G G + C+DV+EC G + C N GS+ C C P
Sbjct: 1719 CNNGYYLLGDSRMFC-TDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVP 1777
Query: 262 GYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG---RRCVDR 318
Y T DG+NC + +C +P + SC G++L+G C++
Sbjct: 1778 SY--TGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLES 1835
Query: 319 DECKELPYVCAGGEC 333
E L C C
Sbjct: 1836 GEWNHLIPYCKAVSC 1850
Score = 58.0 bits (134), Expect = 1e-07
Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 14/113 (12%)
Query: 747 DVDECAAIPGL----CAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+V+EC + P L C G F C C PG+ G C +VDEC +P C +
Sbjct: 1307 EVNECQSNPCLNNAVCEDQVGGFLCKCPPGF--LGTRCGKNVDECLSQPCKNGATCKDGA 1364
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
S+ CLC G+ G++C +++EC+ + Q C + SY C C+ G+
Sbjct: 1365 NSFRCLCAAGF----TGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGF 1413
Score = 48.8 bits (111), Expect = 8e-05
Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 756 GLCAP-GR-FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G C GR + C+C GY G C D+DEC+ P + +C + G + C C +GY
Sbjct: 1206 GTCQQLGRGYVCLCPLGY--TGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGY-- 1261
Query: 813 DEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C + ++EC + IC + Y C+C G+
Sbjct: 1262 --TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGF 1299
Score = 48.4 bits (110), Expect = 1e-04
Identities = 32/105 (30%), Positives = 44/105 (41%), Gaps = 9/105 (8%)
Query: 757 LCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDED 815
L R C + C DVDECAV + C N DGSY C C Y D
Sbjct: 1725 LLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPSY--TGD 1782
Query: 816 GANCRDVDECE-----RDTHTCQQICSNTEGSYECSCEDGYEKRG 855
G NC + +C+ + H+ +I + SC++GY+ G
Sbjct: 1783 GKNCAEPIKCKAPGNPENGHSSGEIYT-VGAEVTFSCQEGYQLMG 1826
Score = 46.0 bits (104), Expect = 6e-04
Identities = 21/50 (42%), Positives = 24/50 (48%), Gaps = 1/50 (2%)
Query: 150 CEDVDECGDQRIC-DHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRP 198
C DVDEC C +H C N GSY C C P YT C + +C P
Sbjct: 1746 CLDVDECAVGSDCSEHASCLNVDGSYICSCVPSYTGDGKNCAEPIKCKAP 1795
Score = 45.6 bits (103), Expect = 8e-04
Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Query: 447 GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT 506
G R C D SC+D DECA+ + +C N G Y C C P +T G +
Sbjct: 1727 GDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPSYT-GDGKN 1785
Query: 507 CVDVDEC 513
C + +C
Sbjct: 1786 CAEPIKC 1792
Score = 45.6 bits (103), Expect = 8e-04
Identities = 33/121 (27%), Positives = 50/121 (41%), Gaps = 10/121 (8%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C + S C DVDEC+ G C A C+N+ G++ C C P Y T C +
Sbjct: 1733 CTDNGSWNGVSPSCLDVDECAVGSD-CSEHASCLNVDGSYICSCVPSY--TGDGKNCAEP 1789
Query: 154 DECGDQRICDHGDCRNTIGSYRCE----CKPGYTL---RENVCRDVDECSRPRPVCRNGT 206
+C ++G I + E C+ GY L + C + E + P C+ +
Sbjct: 1790 IKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVS 1849
Query: 207 C 207
C
Sbjct: 1850 C 1850
Score = 45.2 bits (102), Expect = 0.001
Identities = 47/174 (27%), Positives = 68/174 (39%), Gaps = 25/174 (14%)
Query: 189 CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC 248
C DVDEC+ + +C N+ G+Y+C C + G +C + +C+ G NG
Sbjct: 1746 CLDVDECAVGSDCSEHASCLNVDGSYICSCVPSY-TGDGKNCAEPIKCKAPGNP-ENGHS 1803
Query: 249 RN---TVGS-FRCECAPGYTLTADGR-NCRDVDECDEL-PH----PCGRDGNP--SCTN- 295
TVG+ C GY L + C + E + L P+ CG+ P C
Sbjct: 1804 SGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEE 1863
Query: 296 ---TNGG-YECSCGAGWKLVGRR---CVDRDECKELPYVCAGGEC---RNFNGG 339
T G C G+ L G + C+ P VC +C N N G
Sbjct: 1864 LAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNG 1917
Score = 41.5 bits (93), Expect = 0.012
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC 472
D+DEC V D C+N DGS+ C C Y DG +C + +C
Sbjct: 1748 DVDECAVGSDCSEHASCLNVDGSYICSCVPSY--TGDGKNCAEPIKC 1792
Score = 41.1 bits (92), Expect = 0.016
Identities = 22/70 (31%), Positives = 26/70 (37%), Gaps = 5/70 (7%)
Query: 783 ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEG 841
EC P C Y CLC GY G C D+DEC +C + G
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGY----TGLKCETDIDECSPLPCLNNGVCKDLVG 1251
Query: 842 SYECSCEDGY 851
+ C C GY
Sbjct: 1252 EFICECPSGY 1261
Score = 41.1 bits (92), Expect = 0.016
Identities = 33/117 (28%), Positives = 46/117 (39%), Gaps = 13/117 (11%)
Query: 518 ASCTFRCHN---TAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYI 573
++ T++C+N G R C + C D+DEC HA C NV GSYI
Sbjct: 1713 STVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYI 1772
Query: 574 CKCPEGYRRTSAPQDSENACEDINECE---EQEDLCSGGVCINTDGSFLCDCDAGFE 627
C C Y D +N E I +C+ E+ S G C G++
Sbjct: 1773 CSCVPSY-----TGDGKNCAEPI-KCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQ 1823
Score = 40.7 bits (91), Expect = 0.022
Identities = 22/59 (37%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 498 GFTQGPDQTCVDVDECAEGRASCT--FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDEC 554
G G +C+DVDECA G + C+ C N GS+ C+C Y DG +C + +C
Sbjct: 1737 GSWNGVSPSCLDVDECAVG-SDCSEHASCLNVDGSYICSCVPSY--TGDGKNCAEPIKC 1792
Score = 39.9 bits (89), Expect = 0.038
Identities = 15/46 (32%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
+C D++EC D C+N DGS++C C + + DG +C +
Sbjct: 1745 SCLDVDECAVGSDCSEHASCLNVDGSYICSCVPSY--TGDGKNCAE 1788
Score = 37.5 bits (83), Expect = 0.20
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 818 NCRDVDECERDTHTCQQI-CSNTEGSYECSCEDGYEKRGDAC 858
+C DVDEC + + C N +GSY CSC Y G C
Sbjct: 1745 SCLDVDECAVGSDCSEHASCLNVDGSYICSCVPSYTGDGKNC 1786
Score = 36.3 bits (80), Expect = 0.46
Identities = 15/50 (30%), Positives = 20/50 (40%)
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFD 351
C+ W V C+D DEC C N +G Y+C C + D
Sbjct: 1733 CTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPSYTGD 1782
Score = 35.5 bits (78), Expect = 0.81
Identities = 37/128 (28%), Positives = 49/128 (38%), Gaps = 31/128 (24%)
Query: 188 VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR 247
+CR V C P C+NG P A C C +G+ + + + C GG R
Sbjct: 3470 ICRAV--CRFP---CQNGGICQRPNA--CSCPEGWMGRLCEEPICILPCLNGG------R 3516
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
C V ++C+C PG+T G C C PC G C N C C +
Sbjct: 3517 C---VAPYQCDCPPGWT----GSRCHTA-VCQS---PCLNGG--KCVRPN---RCHCLSS 3560
Query: 308 WKLVGRRC 315
W G C
Sbjct: 3561 W--TGHNC 3566
Score = 34.7 bits (76), Expect = 1.4
Identities = 34/106 (32%), Positives = 40/106 (37%), Gaps = 24/106 (22%)
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCE 343
PC G C N CSC GW +GR C + C LP + GG C Y C+
Sbjct: 3478 PCQNGG--ICQRPNA---CSCPEGW--MGRLC-EEPICI-LPCL-NGGRCV---APYQCD 3524
Query: 344 CPAGWRFDK--TAAV---------CVDERKELCYDEWEAGRCHRAR 378
CP GW + TA CV + C W C R R
Sbjct: 3525 CPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNCSRKR 3570
Score = 33.1 bits (72), Expect = 4.3
Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 3/53 (5%)
Query: 755 PGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNT-DGSYDCLC 806
PG +P CVC GYR +G+ C V A++PP NT + ++ C
Sbjct: 352 PGSTSPED--CVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAAC 402
Score = 32.3 bits (70), Expect = 7.5
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 14/88 (15%)
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPG 498
GG C + C CP+G++ G C + C L C NG Y+C C PG
Sbjct: 3482 GGICQRPNA---CSCPEGWM----GRLC-EEPICILP---CLNG--GRCVAPYQCDCPPG 3528
Query: 499 FTQGPDQTCVDVDECAE-GRASCTFRCH 525
+T T V C G+ RCH
Sbjct: 3529 WTGSRCHTAVCQSPCLNGGKCVRPNRCH 3556
>AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 122 bits (293), Expect = 7e-27
Identities = 82/241 (34%), Positives = 114/241 (47%), Gaps = 34/241 (14%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
GTC G+ C C GY T C D+DECS PC C +L G F C CP
Sbjct: 1183 GTCQQLGRGYVCLCPLGY----TGLKCETDIDECS--PLPCLNNGVCKDLVGEFICECPS 1236
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPR 199
GY T E E+++EC + G C + + YRC C G+ + + +V+EC +
Sbjct: 1237 GY--TGQRCE-ENINECSSSPCLNKGICVDGVAGYRCTCVKGF-VGLHCETEVNEC-QSN 1291
Query: 200 PVCRNGTCENLPGAYLCHCDDGF---KAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSF 255
P N CE+ G +LC C GF + G N V+EC C+NG C++ SF
Sbjct: 1292 PCLNNAVCEDQVGGFLCKCPPGFLGTRCGKN-----VDECL--SQPCKNGATCKDGANSF 1344
Query: 256 RCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR 314
RC CA G+T G +C +++EC +PC +C + Y C C G+ G+R
Sbjct: 1345 RCLCAAGFT----GSHCELNINECQS--NPCRNQA--TCVDELNSYSCKCQPGFS--GKR 1394
Query: 315 C 315
C
Sbjct: 1395 C 1395
Score = 117 bits (281), Expect = 2e-25
Identities = 76/233 (32%), Positives = 112/233 (48%), Gaps = 23/233 (9%)
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCE 177
PC C L + C CP GY +CE D+DEC ++G C++ +G + CE
Sbjct: 1178 PCHNSGTCQQLGRGYVCLCPLGYTGL----KCETDIDECSPLPCLNNGVCKDLVGEFICE 1233
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECR 237
C GYT + +++ECS P G C + Y C C GF G + + +VNEC+
Sbjct: 1234 CPSGYT-GQRCEENINECS-SSPCLNKGICVDGVAGYRCTCVKGF-VGLHCE-TEVNECQ 1289
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTN 297
+ N C + VG F C+C PG+ T G+N VDEC L PC ++G +C +
Sbjct: 1290 SNPCL-NNAVCEDQVGGFLCKCPPGFLGTRCGKN---VDEC--LSQPC-KNG-ATCKDGA 1341
Query: 298 GGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECRNFNGGYVCECPAGW 348
+ C C AG+ G C ++ +EC+ P C C + Y C+C G+
Sbjct: 1342 NSFRCLCAAGF--TGSHCELNINECQSNP--CRNQATCVDELNSYSCKCQPGF 1390
Score = 101 bits (241), Expect = 1e-20
Identities = 67/202 (33%), Positives = 103/202 (50%), Gaps = 24/202 (11%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD-VDECSWGRPPCRGMAQC 126
IDEC +P L G C D F C C GY T C + ++ECS PC C
Sbjct: 1209 IDECSPLPCL-NNGVCKDLVGEFICECPSGY----TGQRCEENINECS--SSPCLNKGIC 1261
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
V+ + C C G+ L CE +V+EC ++ C + +G + C+C PG+ L
Sbjct: 1262 VDGVAGYRCTCVKGF---VGL-HCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGF-LG 1316
Query: 186 ENVCRDVDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC 243
++VDEC S+P C+NG TC++ ++ C C GF G + + +++NEC+ C
Sbjct: 1317 TRCGKNVDECLSQP---CKNGATCKDGANSFRCLCAAGF-TGSHCE-LNINECQSNP--C 1369
Query: 244 RN-GRCRNTVGSFRCECAPGYT 264
RN C + + S+ C+C PG++
Sbjct: 1370 RNQATCVDELNSYSCKCQPGFS 1391
Score = 99 bits (238), Expect = 3e-20
Identities = 74/240 (30%), Positives = 107/240 (44%), Gaps = 32/240 (13%)
Query: 424 TQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGN 481
+Q EC P C G C + C CP GY GL C D DEC+ P + N
Sbjct: 1168 SQVFHECFFNP--CHNSGTCQQLGRGYVCLCPLGYT----GLKCETDIDECSPLPCL-NN 1220
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHNTAGSFRCTCPYGYA 540
G C + G + C+C G+T Q C + ++EC+ C + +RCTC G+
Sbjct: 1221 GVCKDLVGEFICECPSGYT---GQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFV 1277
Query: 541 VAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINEC 599
G+HC +++EC P + CE+ VG ++CKCP G+ T ++++EC
Sbjct: 1278 ----GLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGT-------RCGKNVDEC 1326
Query: 600 EEQEDLCSGGVCINTDGSFLCDCDAGFEPSE---DGTDCID---RRTGTCYRSLVSGRCE 653
Q +G C + SF C C AGF S + +C R TC L S C+
Sbjct: 1327 LSQ-PCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCK 1385
Score = 96.7 bits (230), Expect = 3e-19
Identities = 77/252 (30%), Positives = 113/252 (44%), Gaps = 34/252 (13%)
Query: 155 ECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGTCENLPGA 213
EC + G C+ Y C C GYT + C D+DECS P P NG C++L G
Sbjct: 1173 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLK--CETDIDECS-PLPCLNNGVCKDLVGE 1229
Query: 214 YLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR 273
++C C G+ + ++NEC + G C + V +RC C G+ G +C
Sbjct: 1230 FICECPSGYTGQRCEE--NINECSSSPCL-NKGICVDGVAGYRCTCVKGFV----GLHCE 1282
Query: 274 -DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCA-G 330
+V+EC +PC N C + GG+ C C G+ +G RC + DEC P C G
Sbjct: 1283 TEVNECQS--NPC--LNNAVCEDQVGGFLCKCPPGF--LGTRCGKNVDECLSQP--CKNG 1334
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPL--QLARPECC 388
C++ + C C AG+ T + C EL +E ++ C +L C
Sbjct: 1335 ATCKDGANSFRCLCAAGF----TGSHC-----ELNINECQSNPCRNQATCVDELNSYSCK 1385
Query: 389 CSEGAAWGRYCE 400
C G + G+ CE
Sbjct: 1386 CQPGFS-GKRCE 1396
Score = 96.7 bits (230), Expect = 3e-19
Identities = 67/222 (30%), Positives = 99/222 (44%), Gaps = 28/222 (12%)
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
++ +C G D+DEC P C+ G C + G F CECP GY G C +
Sbjct: 1192 YVCLCPLGYTGLKCETDIDECSPLP--CLNNGVCKDLVGEFICECPSGYT----GQRCEE 1245
Query: 469 -ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNT 527
+EC+ P + G C + GY C C GF +T +V+EC C +
Sbjct: 1246 NINECSSSPCL-NKGICVDGVAGYRCTCVKGFVGLHCET--EVNECQSNPCLNNAVCEDQ 1302
Query: 528 AGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAP 586
G F C CP G+ G C +++DEC+ +P C++ S+ C C G+
Sbjct: 1303 VGGFLCKCPPGFL----GTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGF------ 1352
Query: 587 QDSENACE-DINECEEQEDLCSG-GVCINTDGSFLCDCDAGF 626
+ + CE +INEC Q + C C++ S+ C C GF
Sbjct: 1353 --TGSHCELNINEC--QSNPCRNQATCVDELNSYSCKCQPGF 1390
Score = 92.7 bits (220), Expect = 5e-18
Identities = 57/175 (32%), Positives = 82/175 (46%), Gaps = 16/175 (9%)
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSC- 466
EF+ C G ++++EC P C+ G CV+ +RC C G+V GL C
Sbjct: 1229 EFICECPSGYTGQRCEENINECSSSP--CLNKGICVDGVAGYRCTCVKGFV----GLHCE 1282
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHN 526
+ +EC +P + N C + GG+ C+C PGF + +VDEC C +
Sbjct: 1283 TEVNECQSNPCL-NNAVCEDQVGGFLCKCPPGFLG--TRCGKNVDECLSQPCKNGATCKD 1339
Query: 527 TAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGY 580
A SFRC C G+ G HC +I+EC P C + + SY CKC G+
Sbjct: 1340 GANSFRCLCAAGFT----GSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGF 1390
Score = 82.2 bits (194), Expect = 7e-15
Identities = 68/232 (29%), Positives = 97/232 (41%), Gaps = 31/232 (13%)
Query: 283 HPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYV 341
+PC G +C GY C C G+ G +C D DEC LP + G C++ G ++
Sbjct: 1177 NPCHNSG--TCQQLGRGYVCLCPLGY--TGLKCETDIDECSPLPCL-NNGVCKDLVGEFI 1231
Query: 342 CECPAGW---RFDKTAAVCVDE---RKELCYDEWEAGRCHRARPLQLARPEC----CCSE 391
CECP+G+ R ++ C K +C D RC + E C S
Sbjct: 1232 CECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN 1291
Query: 392 GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFR 450
CE F+ C G +++DEC +P C G C + SFR
Sbjct: 1292 PCLNNAVCE----DQVGGFLCKCPPGFLGTRCGKNVDECLSQP--CKNGATCKDGANSFR 1345
Query: 451 CECPDGYVLAPDGLSC-VDADECALDPRICGN-GTCSNTRGGYECQCSPGFT 500
C C G+ G C ++ +EC +P C N TC + Y C+C PGF+
Sbjct: 1346 CLCAAGFT----GSHCELNINECQSNP--CRNQATCVDELNSYSCKCQPGFS 1391
Score = 61.7 bits (143), Expect = 1e-08
Identities = 56/220 (25%), Positives = 87/220 (39%), Gaps = 21/220 (9%)
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKEL-------CYDEWEAGRCHRARPLQLA 383
G C+ GYVC CP G+ K +DE L C D C
Sbjct: 1183 GTCQQLGRGYVCLCPLGYTGLK-CETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQ 1241
Query: 384 RPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-C 442
R E +E ++ + A + C G + +++EC+ P C+ C
Sbjct: 1242 RCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNP--CLNNAVC 1299
Query: 443 VNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNG-TCSNTRGGYECQCSPGFT 500
+ G F C+CP G++ G C + DEC P C NG TC + + C C+ GFT
Sbjct: 1300 EDQVGGFLCKCPPGFL----GTRCGKNVDECLSQP--CKNGATCKDGANSFRCLCAAGFT 1353
Query: 501 QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA 540
+ ++++EC C + S+ C C G++
Sbjct: 1354 GSHCE--LNINECQSNPCRNQATCVDELNSYSCKCQPGFS 1391
Score = 60.1 bits (139), Expect = 3e-08
Identities = 38/135 (28%), Positives = 54/135 (40%), Gaps = 6/135 (4%)
Query: 202 CRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAP 261
C NG C D+G G + C+DV+EC G + C N GS+ C C P
Sbjct: 1693 CNNGYYLLGDSRMFC-TDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVP 1751
Query: 262 GYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG---RRCVDR 318
Y T DG+NC + +C +P + SC G++L+G C++
Sbjct: 1752 PY--TGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLES 1809
Query: 319 DECKELPYVCAGGEC 333
E L C C
Sbjct: 1810 GEWNHLIPYCKAVSC 1824
Score = 58.0 bits (134), Expect = 1e-07
Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 14/113 (12%)
Query: 747 DVDECAAIPGL----CAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+V+EC + P L C G F C C PG+ G C +VDEC +P C +
Sbjct: 1284 EVNECQSNPCLNNAVCEDQVGGFLCKCPPGF--LGTRCGKNVDECLSQPCKNGATCKDGA 1341
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
S+ CLC G+ G++C +++EC+ + Q C + SY C C+ G+
Sbjct: 1342 NSFRCLCAAGF----TGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGF 1390
Score = 48.8 bits (111), Expect = 8e-05
Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 756 GLCAP-GR-FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G C GR + C+C GY G C D+DEC+ P + +C + G + C C +GY
Sbjct: 1183 GTCQQLGRGYVCLCPLGY--TGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGY-- 1238
Query: 813 DEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C + ++EC + IC + Y C+C G+
Sbjct: 1239 --TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGF 1276
Score = 47.6 bits (108), Expect = 2e-04
Identities = 32/105 (30%), Positives = 44/105 (41%), Gaps = 9/105 (8%)
Query: 757 LCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDED 815
L R C + C DVDECAV + C N DGSY C C Y D
Sbjct: 1699 LLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPY--TGD 1756
Query: 816 GANCRDVDECE-----RDTHTCQQICSNTEGSYECSCEDGYEKRG 855
G NC + +C+ + H+ +I + SC++GY+ G
Sbjct: 1757 GKNCAEPIKCKAPGNPENGHSSGEIYT-VGAEVTFSCQEGYQLMG 1800
Score = 45.2 bits (102), Expect = 0.001
Identities = 21/50 (42%), Positives = 24/50 (48%), Gaps = 1/50 (2%)
Query: 150 CEDVDECGDQRIC-DHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRP 198
C DVDEC C +H C N GSY C C P YT C + +C P
Sbjct: 1720 CLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAP 1769
Score = 44.8 bits (101), Expect = 0.001
Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Query: 447 GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT 506
G R C D SC+D DECA+ + +C N G Y C C P +T G +
Sbjct: 1701 GDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYT-GDGKN 1759
Query: 507 CVDVDEC 513
C + +C
Sbjct: 1760 CAEPIKC 1766
Score = 44.8 bits (101), Expect = 0.001
Identities = 33/121 (27%), Positives = 50/121 (41%), Gaps = 10/121 (8%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C + S C DVDEC+ G C A C+N+ G++ C C P Y T C +
Sbjct: 1707 CTDNGSWNGVSPSCLDVDECAVGSD-CSEHASCLNVDGSYICSCVPPY--TGDGKNCAEP 1763
Query: 154 DECGDQRICDHGDCRNTIGSYRCE----CKPGYTL---RENVCRDVDECSRPRPVCRNGT 206
+C ++G I + E C+ GY L + C + E + P C+ +
Sbjct: 1764 IKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVS 1823
Query: 207 C 207
C
Sbjct: 1824 C 1824
Score = 44.4 bits (100), Expect = 0.002
Identities = 47/174 (27%), Positives = 68/174 (39%), Gaps = 25/174 (14%)
Query: 189 CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC 248
C DVDEC+ + +C N+ G+Y+C C + G +C + +C+ G NG
Sbjct: 1720 CLDVDECAVGSDCSEHASCLNVDGSYICSCVPPY-TGDGKNCAEPIKCKAPGNP-ENGHS 1777
Query: 249 RN---TVGS-FRCECAPGYTLTADGR-NCRDVDECDEL-PH----PCGRDGNP--SCTN- 295
TVG+ C GY L + C + E + L P+ CG+ P C
Sbjct: 1778 SGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEE 1837
Query: 296 ---TNGG-YECSCGAGWKLVGRR---CVDRDECKELPYVCAGGEC---RNFNGG 339
T G C G+ L G + C+ P VC +C N N G
Sbjct: 1838 LAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNG 1891
Score = 41.1 bits (92), Expect = 0.016
Identities = 22/70 (31%), Positives = 26/70 (37%), Gaps = 5/70 (7%)
Query: 783 ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEG 841
EC P C Y CLC GY G C D+DEC +C + G
Sbjct: 1173 ECFFNPCHNSGTCQQLGRGYVCLCPLGY----TGLKCETDIDECSPLPCLNNGVCKDLVG 1228
Query: 842 SYECSCEDGY 851
+ C C GY
Sbjct: 1229 EFICECPSGY 1238
Score = 40.7 bits (91), Expect = 0.022
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC 472
D+DEC V D C+N DGS+ C C Y DG +C + +C
Sbjct: 1722 DVDECAVGSDCSEHASCLNVDGSYICSCVPPY--TGDGKNCAEPIKC 1766
Score = 40.3 bits (90), Expect = 0.028
Identities = 33/117 (28%), Positives = 46/117 (39%), Gaps = 13/117 (11%)
Query: 518 ASCTFRCHN---TAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYI 573
++ T++C+N G R C + C D+DEC HA C NV GSYI
Sbjct: 1687 STVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYI 1746
Query: 574 CKCPEGYRRTSAPQDSENACEDINECE---EQEDLCSGGVCINTDGSFLCDCDAGFE 627
C C Y D +N E I +C+ E+ S G C G++
Sbjct: 1747 CSCVPPY-----TGDGKNCAEPI-KCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQ 1797
Score = 39.9 bits (89), Expect = 0.038
Identities = 22/59 (37%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 498 GFTQGPDQTCVDVDECAEGRASCT--FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDEC 554
G G +C+DVDECA G + C+ C N GS+ C+C Y DG +C + +C
Sbjct: 1711 GSWNGVSPSCLDVDECAVG-SDCSEHASCLNVDGSYICSCVPPY--TGDGKNCAEPIKC 1766
Score = 39.1 bits (87), Expect = 0.066
Identities = 15/46 (32%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
+C D++EC D C+N DGS++C C + + DG +C +
Sbjct: 1719 SCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPY--TGDGKNCAE 1762
Score = 38.3 bits (85), Expect = 0.11
Identities = 51/194 (26%), Positives = 70/194 (36%), Gaps = 43/194 (22%)
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSY----RCECKPGYTLR---ENVC 189
C P T + +CE + CG ++ R Y C GY L +VC
Sbjct: 3375 CNPDETWTQTSAKCEKIS-CGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVC 3433
Query: 190 RDVDECSRP---RPVCR-----NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGM 241
+ + P R VCR G C+ P A C C +G+ + + + C GG
Sbjct: 3434 LENGTWTSPPICRAVCRFPCQNGGICQR-PNA--CSCPEGWMGRLCEEPICILPCLNGG- 3489
Query: 242 VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
RC V ++C+C PG+T G C C PC G C N
Sbjct: 3490 -----RC---VAPYQCDCPPGWT----GSRCHTA-VCQS---PCLNGG--KCVRPN---R 3528
Query: 302 CSCGAGWKLVGRRC 315
C C + W G C
Sbjct: 3529 CHCLSSW--TGHNC 3540
Score = 36.7 bits (81), Expect = 0.35
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 818 NCRDVDECERDTHTCQQI-CSNTEGSYECSCEDGYEKRGDAC 858
+C DVDEC + + C N +GSY CSC Y G C
Sbjct: 1719 SCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNC 1760
Score = 35.9 bits (79), Expect = 0.61
Identities = 14/43 (32%), Positives = 18/43 (41%)
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
C+ W V C+D DEC C N +G Y+C C
Sbjct: 1707 CTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSC 1749
Score = 34.7 bits (76), Expect = 1.4
Identities = 34/106 (32%), Positives = 40/106 (37%), Gaps = 24/106 (22%)
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCE 343
PC G C N CSC GW +GR C + C LP + GG C Y C+
Sbjct: 3452 PCQNGG--ICQRPNA---CSCPEGW--MGRLC-EEPICI-LPCL-NGGRCV---APYQCD 3498
Query: 344 CPAGWRFDK--TAAV---------CVDERKELCYDEWEAGRCHRAR 378
CP GW + TA CV + C W C R R
Sbjct: 3499 CPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNCSRKR 3544
Score = 33.1 bits (72), Expect = 4.3
Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 3/53 (5%)
Query: 755 PGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNT-DGSYDCLC 806
PG +P CVC GYR +G+ C V A++PP NT + ++ C
Sbjct: 329 PGSTSPED--CVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAAC 379
Score = 32.3 bits (70), Expect = 7.5
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 14/88 (15%)
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPG 498
GG C + C CP+G++ G C + C L C NG Y+C C PG
Sbjct: 3456 GGICQRPNA---CSCPEGWM----GRLC-EEPICILP---CLNG--GRCVAPYQCDCPPG 3502
Query: 499 FTQGPDQTCVDVDECAE-GRASCTFRCH 525
+T T V C G+ RCH
Sbjct: 3503 WTGSRCHTAVCQSPCLNGGKCVRPNRCH 3530
>AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 122 bits (293), Expect = 7e-27
Identities = 82/241 (34%), Positives = 114/241 (47%), Gaps = 34/241 (14%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
GTC G+ C C GY T C D+DECS PC C +L G F C CP
Sbjct: 1183 GTCQQLGRGYVCLCPLGY----TGLKCETDIDECS--PLPCLNNGVCKDLVGEFICECPS 1236
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPR 199
GY T E E+++EC + G C + + YRC C G+ + + +V+EC +
Sbjct: 1237 GY--TGQRCE-ENINECSSSPCLNKGICVDGVAGYRCTCVKGF-VGLHCETEVNEC-QSN 1291
Query: 200 PVCRNGTCENLPGAYLCHCDDGF---KAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSF 255
P N CE+ G +LC C GF + G N V+EC C+NG C++ SF
Sbjct: 1292 PCLNNAVCEDQVGGFLCKCPPGFLGTRCGKN-----VDECL--SQPCKNGATCKDGANSF 1344
Query: 256 RCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR 314
RC CA G+T G +C +++EC +PC +C + Y C C G+ G+R
Sbjct: 1345 RCLCAAGFT----GSHCELNINECQS--NPCRNQA--TCVDELNSYSCKCQPGFS--GKR 1394
Query: 315 C 315
C
Sbjct: 1395 C 1395
Score = 117 bits (281), Expect = 2e-25
Identities = 76/233 (32%), Positives = 112/233 (48%), Gaps = 23/233 (9%)
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCE 177
PC C L + C CP GY +CE D+DEC ++G C++ +G + CE
Sbjct: 1178 PCHNSGTCQQLGRGYVCLCPLGYTGL----KCETDIDECSPLPCLNNGVCKDLVGEFICE 1233
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECR 237
C GYT + +++ECS P G C + Y C C GF G + + +VNEC+
Sbjct: 1234 CPSGYT-GQRCEENINECS-SSPCLNKGICVDGVAGYRCTCVKGF-VGLHCE-TEVNECQ 1289
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTN 297
+ N C + VG F C+C PG+ T G+N VDEC L PC ++G +C +
Sbjct: 1290 SNPCL-NNAVCEDQVGGFLCKCPPGFLGTRCGKN---VDEC--LSQPC-KNG-ATCKDGA 1341
Query: 298 GGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECRNFNGGYVCECPAGW 348
+ C C AG+ G C ++ +EC+ P C C + Y C+C G+
Sbjct: 1342 NSFRCLCAAGF--TGSHCELNINECQSNP--CRNQATCVDELNSYSCKCQPGF 1390
Score = 101 bits (241), Expect = 1e-20
Identities = 67/202 (33%), Positives = 103/202 (50%), Gaps = 24/202 (11%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD-VDECSWGRPPCRGMAQC 126
IDEC +P L G C D F C C GY T C + ++ECS PC C
Sbjct: 1209 IDECSPLPCL-NNGVCKDLVGEFICECPSGY----TGQRCEENINECS--SSPCLNKGIC 1261
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
V+ + C C G+ L CE +V+EC ++ C + +G + C+C PG+ L
Sbjct: 1262 VDGVAGYRCTCVKGF---VGL-HCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGF-LG 1316
Query: 186 ENVCRDVDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC 243
++VDEC S+P C+NG TC++ ++ C C GF G + + +++NEC+ C
Sbjct: 1317 TRCGKNVDECLSQP---CKNGATCKDGANSFRCLCAAGF-TGSHCE-LNINECQSNP--C 1369
Query: 244 RN-GRCRNTVGSFRCECAPGYT 264
RN C + + S+ C+C PG++
Sbjct: 1370 RNQATCVDELNSYSCKCQPGFS 1391
Score = 99 bits (238), Expect = 3e-20
Identities = 74/240 (30%), Positives = 107/240 (44%), Gaps = 32/240 (13%)
Query: 424 TQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGN 481
+Q EC P C G C + C CP GY GL C D DEC+ P + N
Sbjct: 1168 SQVFHECFFNP--CHNSGTCQQLGRGYVCLCPLGYT----GLKCETDIDECSPLPCL-NN 1220
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHNTAGSFRCTCPYGYA 540
G C + G + C+C G+T Q C + ++EC+ C + +RCTC G+
Sbjct: 1221 GVCKDLVGEFICECPSGYT---GQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFV 1277
Query: 541 VAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINEC 599
G+HC +++EC P + CE+ VG ++CKCP G+ T ++++EC
Sbjct: 1278 ----GLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGT-------RCGKNVDEC 1326
Query: 600 EEQEDLCSGGVCINTDGSFLCDCDAGFEPSE---DGTDCID---RRTGTCYRSLVSGRCE 653
Q +G C + SF C C AGF S + +C R TC L S C+
Sbjct: 1327 LSQ-PCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCK 1385
Score = 96.7 bits (230), Expect = 3e-19
Identities = 77/252 (30%), Positives = 113/252 (44%), Gaps = 34/252 (13%)
Query: 155 ECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGTCENLPGA 213
EC + G C+ Y C C GYT + C D+DECS P P NG C++L G
Sbjct: 1173 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLK--CETDIDECS-PLPCLNNGVCKDLVGE 1229
Query: 214 YLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR 273
++C C G+ + ++NEC + G C + V +RC C G+ G +C
Sbjct: 1230 FICECPSGYTGQRCEE--NINECSSSPCL-NKGICVDGVAGYRCTCVKGFV----GLHCE 1282
Query: 274 -DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCA-G 330
+V+EC +PC N C + GG+ C C G+ +G RC + DEC P C G
Sbjct: 1283 TEVNECQS--NPC--LNNAVCEDQVGGFLCKCPPGF--LGTRCGKNVDECLSQP--CKNG 1334
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPL--QLARPECC 388
C++ + C C AG+ T + C EL +E ++ C +L C
Sbjct: 1335 ATCKDGANSFRCLCAAGF----TGSHC-----ELNINECQSNPCRNQATCVDELNSYSCK 1385
Query: 389 CSEGAAWGRYCE 400
C G + G+ CE
Sbjct: 1386 CQPGFS-GKRCE 1396
Score = 96.7 bits (230), Expect = 3e-19
Identities = 67/222 (30%), Positives = 99/222 (44%), Gaps = 28/222 (12%)
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
++ +C G D+DEC P C+ G C + G F CECP GY G C +
Sbjct: 1192 YVCLCPLGYTGLKCETDIDECSPLP--CLNNGVCKDLVGEFICECPSGYT----GQRCEE 1245
Query: 469 -ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNT 527
+EC+ P + G C + GY C C GF +T +V+EC C +
Sbjct: 1246 NINECSSSPCL-NKGICVDGVAGYRCTCVKGFVGLHCET--EVNECQSNPCLNNAVCEDQ 1302
Query: 528 AGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAP 586
G F C CP G+ G C +++DEC+ +P C++ S+ C C G+
Sbjct: 1303 VGGFLCKCPPGFL----GTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGF------ 1352
Query: 587 QDSENACE-DINECEEQEDLCSG-GVCINTDGSFLCDCDAGF 626
+ + CE +INEC Q + C C++ S+ C C GF
Sbjct: 1353 --TGSHCELNINEC--QSNPCRNQATCVDELNSYSCKCQPGF 1390
Score = 92.7 bits (220), Expect = 5e-18
Identities = 57/175 (32%), Positives = 82/175 (46%), Gaps = 16/175 (9%)
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSC- 466
EF+ C G ++++EC P C+ G CV+ +RC C G+V GL C
Sbjct: 1229 EFICECPSGYTGQRCEENINECSSSP--CLNKGICVDGVAGYRCTCVKGFV----GLHCE 1282
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHN 526
+ +EC +P + N C + GG+ C+C PGF + +VDEC C +
Sbjct: 1283 TEVNECQSNPCL-NNAVCEDQVGGFLCKCPPGFLG--TRCGKNVDECLSQPCKNGATCKD 1339
Query: 527 TAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGY 580
A SFRC C G+ G HC +I+EC P C + + SY CKC G+
Sbjct: 1340 GANSFRCLCAAGFT----GSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGF 1390
Score = 82.2 bits (194), Expect = 7e-15
Identities = 68/232 (29%), Positives = 97/232 (41%), Gaps = 31/232 (13%)
Query: 283 HPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYV 341
+PC G +C GY C C G+ G +C D DEC LP + G C++ G ++
Sbjct: 1177 NPCHNSG--TCQQLGRGYVCLCPLGY--TGLKCETDIDECSPLPCL-NNGVCKDLVGEFI 1231
Query: 342 CECPAGW---RFDKTAAVCVDE---RKELCYDEWEAGRCHRARPLQLARPEC----CCSE 391
CECP+G+ R ++ C K +C D RC + E C S
Sbjct: 1232 CECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN 1291
Query: 392 GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFR 450
CE F+ C G +++DEC +P C G C + SFR
Sbjct: 1292 PCLNNAVCE----DQVGGFLCKCPPGFLGTRCGKNVDECLSQP--CKNGATCKDGANSFR 1345
Query: 451 CECPDGYVLAPDGLSC-VDADECALDPRICGN-GTCSNTRGGYECQCSPGFT 500
C C G+ G C ++ +EC +P C N TC + Y C+C PGF+
Sbjct: 1346 CLCAAGFT----GSHCELNINECQSNP--CRNQATCVDELNSYSCKCQPGFS 1391
Score = 61.7 bits (143), Expect = 1e-08
Identities = 56/220 (25%), Positives = 87/220 (39%), Gaps = 21/220 (9%)
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKEL-------CYDEWEAGRCHRARPLQLA 383
G C+ GYVC CP G+ K +DE L C D C
Sbjct: 1183 GTCQQLGRGYVCLCPLGYTGLK-CETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQ 1241
Query: 384 RPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-C 442
R E +E ++ + A + C G + +++EC+ P C+ C
Sbjct: 1242 RCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNP--CLNNAVC 1299
Query: 443 VNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNG-TCSNTRGGYECQCSPGFT 500
+ G F C+CP G++ G C + DEC P C NG TC + + C C+ GFT
Sbjct: 1300 EDQVGGFLCKCPPGFL----GTRCGKNVDECLSQP--CKNGATCKDGANSFRCLCAAGFT 1353
Query: 501 QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA 540
+ ++++EC C + S+ C C G++
Sbjct: 1354 GSHCE--LNINECQSNPCRNQATCVDELNSYSCKCQPGFS 1391
Score = 60.1 bits (139), Expect = 3e-08
Identities = 38/135 (28%), Positives = 54/135 (40%), Gaps = 6/135 (4%)
Query: 202 CRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAP 261
C NG C D+G G + C+DV+EC G + C N GS+ C C P
Sbjct: 1693 CNNGYYLLGDSRMFC-TDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVP 1751
Query: 262 GYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG---RRCVDR 318
Y T DG+NC + +C +P + SC G++L+G C++
Sbjct: 1752 PY--TGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLES 1809
Query: 319 DECKELPYVCAGGEC 333
E L C C
Sbjct: 1810 GEWNHLIPYCKAVSC 1824
Score = 58.0 bits (134), Expect = 1e-07
Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 14/113 (12%)
Query: 747 DVDECAAIPGL----CAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+V+EC + P L C G F C C PG+ G C +VDEC +P C +
Sbjct: 1284 EVNECQSNPCLNNAVCEDQVGGFLCKCPPGF--LGTRCGKNVDECLSQPCKNGATCKDGA 1341
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
S+ CLC G+ G++C +++EC+ + Q C + SY C C+ G+
Sbjct: 1342 NSFRCLCAAGF----TGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGF 1390
Score = 48.8 bits (111), Expect = 8e-05
Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 756 GLCAP-GR-FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G C GR + C+C GY G C D+DEC+ P + +C + G + C C +GY
Sbjct: 1183 GTCQQLGRGYVCLCPLGY--TGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGY-- 1238
Query: 813 DEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C + ++EC + IC + Y C+C G+
Sbjct: 1239 --TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGF 1276
Score = 47.6 bits (108), Expect = 2e-04
Identities = 32/105 (30%), Positives = 44/105 (41%), Gaps = 9/105 (8%)
Query: 757 LCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDED 815
L R C + C DVDECAV + C N DGSY C C Y D
Sbjct: 1699 LLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPY--TGD 1756
Query: 816 GANCRDVDECE-----RDTHTCQQICSNTEGSYECSCEDGYEKRG 855
G NC + +C+ + H+ +I + SC++GY+ G
Sbjct: 1757 GKNCAEPIKCKAPGNPENGHSSGEIYT-VGAEVTFSCQEGYQLMG 1800
Score = 45.2 bits (102), Expect = 0.001
Identities = 21/50 (42%), Positives = 24/50 (48%), Gaps = 1/50 (2%)
Query: 150 CEDVDECGDQRIC-DHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRP 198
C DVDEC C +H C N GSY C C P YT C + +C P
Sbjct: 1720 CLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAP 1769
Score = 44.8 bits (101), Expect = 0.001
Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Query: 447 GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT 506
G R C D SC+D DECA+ + +C N G Y C C P +T G +
Sbjct: 1701 GDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYT-GDGKN 1759
Query: 507 CVDVDEC 513
C + +C
Sbjct: 1760 CAEPIKC 1766
Score = 44.8 bits (101), Expect = 0.001
Identities = 33/121 (27%), Positives = 50/121 (41%), Gaps = 10/121 (8%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C + S C DVDEC+ G C A C+N+ G++ C C P Y T C +
Sbjct: 1707 CTDNGSWNGVSPSCLDVDECAVGSD-CSEHASCLNVDGSYICSCVPPY--TGDGKNCAEP 1763
Query: 154 DECGDQRICDHGDCRNTIGSYRCE----CKPGYTL---RENVCRDVDECSRPRPVCRNGT 206
+C ++G I + E C+ GY L + C + E + P C+ +
Sbjct: 1764 IKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVS 1823
Query: 207 C 207
C
Sbjct: 1824 C 1824
Score = 44.4 bits (100), Expect = 0.002
Identities = 47/174 (27%), Positives = 68/174 (39%), Gaps = 25/174 (14%)
Query: 189 CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC 248
C DVDEC+ + +C N+ G+Y+C C + G +C + +C+ G NG
Sbjct: 1720 CLDVDECAVGSDCSEHASCLNVDGSYICSCVPPY-TGDGKNCAEPIKCKAPGNP-ENGHS 1777
Query: 249 RN---TVGS-FRCECAPGYTLTADGR-NCRDVDECDEL-PH----PCGRDGNP--SCTN- 295
TVG+ C GY L + C + E + L P+ CG+ P C
Sbjct: 1778 SGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEE 1837
Query: 296 ---TNGG-YECSCGAGWKLVGRR---CVDRDECKELPYVCAGGEC---RNFNGG 339
T G C G+ L G + C+ P VC +C N N G
Sbjct: 1838 LAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNG 1891
Score = 41.1 bits (92), Expect = 0.016
Identities = 22/70 (31%), Positives = 26/70 (37%), Gaps = 5/70 (7%)
Query: 783 ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEG 841
EC P C Y CLC GY G C D+DEC +C + G
Sbjct: 1173 ECFFNPCHNSGTCQQLGRGYVCLCPLGY----TGLKCETDIDECSPLPCLNNGVCKDLVG 1228
Query: 842 SYECSCEDGY 851
+ C C GY
Sbjct: 1229 EFICECPSGY 1238
Score = 40.7 bits (91), Expect = 0.022
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC 472
D+DEC V D C+N DGS+ C C Y DG +C + +C
Sbjct: 1722 DVDECAVGSDCSEHASCLNVDGSYICSCVPPY--TGDGKNCAEPIKC 1766
Score = 40.3 bits (90), Expect = 0.028
Identities = 33/117 (28%), Positives = 46/117 (39%), Gaps = 13/117 (11%)
Query: 518 ASCTFRCHN---TAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYI 573
++ T++C+N G R C + C D+DEC HA C NV GSYI
Sbjct: 1687 STVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYI 1746
Query: 574 CKCPEGYRRTSAPQDSENACEDINECE---EQEDLCSGGVCINTDGSFLCDCDAGFE 627
C C Y D +N E I +C+ E+ S G C G++
Sbjct: 1747 CSCVPPY-----TGDGKNCAEPI-KCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQ 1797
Score = 39.9 bits (89), Expect = 0.038
Identities = 22/59 (37%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 498 GFTQGPDQTCVDVDECAEGRASCT--FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDEC 554
G G +C+DVDECA G + C+ C N GS+ C+C Y DG +C + +C
Sbjct: 1711 GSWNGVSPSCLDVDECAVG-SDCSEHASCLNVDGSYICSCVPPY--TGDGKNCAEPIKC 1766
Score = 39.1 bits (87), Expect = 0.066
Identities = 15/46 (32%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
+C D++EC D C+N DGS++C C + + DG +C +
Sbjct: 1719 SCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPY--TGDGKNCAE 1762
Score = 38.3 bits (85), Expect = 0.11
Identities = 51/194 (26%), Positives = 70/194 (36%), Gaps = 43/194 (22%)
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSY----RCECKPGYTLR---ENVC 189
C P T + +CE + CG ++ R Y C GY L +VC
Sbjct: 3375 CNPDETWTQTSAKCEKIS-CGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVC 3433
Query: 190 RDVDECSRP---RPVCR-----NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGM 241
+ + P R VCR G C+ P A C C +G+ + + + C GG
Sbjct: 3434 LENGTWTSPPICRAVCRFPCQNGGICQR-PNA--CSCPEGWMGRLCEEPICILPCLNGG- 3489
Query: 242 VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
RC V ++C+C PG+T G C C PC G C N
Sbjct: 3490 -----RC---VAPYQCDCPPGWT----GSRCHTA-VCQS---PCLNGG--KCVRPN---R 3528
Query: 302 CSCGAGWKLVGRRC 315
C C + W G C
Sbjct: 3529 CHCLSSW--TGHNC 3540
Score = 36.7 bits (81), Expect = 0.35
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 818 NCRDVDECERDTHTCQQI-CSNTEGSYECSCEDGYEKRGDAC 858
+C DVDEC + + C N +GSY CSC Y G C
Sbjct: 1719 SCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNC 1760
Score = 35.9 bits (79), Expect = 0.61
Identities = 14/43 (32%), Positives = 18/43 (41%)
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
C+ W V C+D DEC C N +G Y+C C
Sbjct: 1707 CTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSC 1749
Score = 34.7 bits (76), Expect = 1.4
Identities = 34/106 (32%), Positives = 40/106 (37%), Gaps = 24/106 (22%)
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCE 343
PC G C N CSC GW +GR C + C LP + GG C Y C+
Sbjct: 3452 PCQNGG--ICQRPNA---CSCPEGW--MGRLC-EEPICI-LPCL-NGGRCV---APYQCD 3498
Query: 344 CPAGWRFDK--TAAV---------CVDERKELCYDEWEAGRCHRAR 378
CP GW + TA CV + C W C R R
Sbjct: 3499 CPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNCSRKR 3544
Score = 33.1 bits (72), Expect = 4.3
Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 3/53 (5%)
Query: 755 PGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNT-DGSYDCLC 806
PG +P CVC GYR +G+ C V A++PP NT + ++ C
Sbjct: 329 PGSTSPED--CVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAAC 379
Score = 32.3 bits (70), Expect = 7.5
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 14/88 (15%)
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPG 498
GG C + C CP+G++ G C + C L C NG Y+C C PG
Sbjct: 3456 GGICQRPNA---CSCPEGWM----GRLC-EEPICILP---CLNG--GRCVAPYQCDCPPG 3502
Query: 499 FTQGPDQTCVDVDECAE-GRASCTFRCH 525
+T T V C G+ RCH
Sbjct: 3503 WTGSRCHTAVCQSPCLNGGKCVRPNRCH 3530
>AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 122 bits (293), Expect = 7e-27
Identities = 82/241 (34%), Positives = 114/241 (47%), Gaps = 34/241 (14%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
GTC G+ C C GY T C D+DECS PC C +L G F C CP
Sbjct: 1183 GTCQQLGRGYVCLCPLGY----TGLKCETDIDECS--PLPCLNNGVCKDLVGEFICECPS 1236
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPR 199
GY T E E+++EC + G C + + YRC C G+ + + +V+EC +
Sbjct: 1237 GY--TGQRCE-ENINECSSSPCLNKGICVDGVAGYRCTCVKGF-VGLHCETEVNEC-QSN 1291
Query: 200 PVCRNGTCENLPGAYLCHCDDGF---KAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSF 255
P N CE+ G +LC C GF + G N V+EC C+NG C++ SF
Sbjct: 1292 PCLNNAVCEDQVGGFLCKCPPGFLGTRCGKN-----VDECL--SQPCKNGATCKDGANSF 1344
Query: 256 RCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR 314
RC CA G+T G +C +++EC +PC +C + Y C C G+ G+R
Sbjct: 1345 RCLCAAGFT----GSHCELNINECQS--NPCRNQA--TCVDELNSYSCKCQPGFS--GKR 1394
Query: 315 C 315
C
Sbjct: 1395 C 1395
Score = 117 bits (281), Expect = 2e-25
Identities = 76/233 (32%), Positives = 112/233 (48%), Gaps = 23/233 (9%)
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCE 177
PC C L + C CP GY +CE D+DEC ++G C++ +G + CE
Sbjct: 1178 PCHNSGTCQQLGRGYVCLCPLGYTGL----KCETDIDECSPLPCLNNGVCKDLVGEFICE 1233
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECR 237
C GYT + +++ECS P G C + Y C C GF G + + +VNEC+
Sbjct: 1234 CPSGYT-GQRCEENINECS-SSPCLNKGICVDGVAGYRCTCVKGF-VGLHCE-TEVNECQ 1289
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTN 297
+ N C + VG F C+C PG+ T G+N VDEC L PC ++G +C +
Sbjct: 1290 SNPCL-NNAVCEDQVGGFLCKCPPGFLGTRCGKN---VDEC--LSQPC-KNG-ATCKDGA 1341
Query: 298 GGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECRNFNGGYVCECPAGW 348
+ C C AG+ G C ++ +EC+ P C C + Y C+C G+
Sbjct: 1342 NSFRCLCAAGF--TGSHCELNINECQSNP--CRNQATCVDELNSYSCKCQPGF 1390
Score = 101 bits (241), Expect = 1e-20
Identities = 67/202 (33%), Positives = 103/202 (50%), Gaps = 24/202 (11%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD-VDECSWGRPPCRGMAQC 126
IDEC +P L G C D F C C GY T C + ++ECS PC C
Sbjct: 1209 IDECSPLPCL-NNGVCKDLVGEFICECPSGY----TGQRCEENINECS--SSPCLNKGIC 1261
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
V+ + C C G+ L CE +V+EC ++ C + +G + C+C PG+ L
Sbjct: 1262 VDGVAGYRCTCVKGF---VGL-HCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGF-LG 1316
Query: 186 ENVCRDVDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC 243
++VDEC S+P C+NG TC++ ++ C C GF G + + +++NEC+ C
Sbjct: 1317 TRCGKNVDECLSQP---CKNGATCKDGANSFRCLCAAGF-TGSHCE-LNINECQSNP--C 1369
Query: 244 RN-GRCRNTVGSFRCECAPGYT 264
RN C + + S+ C+C PG++
Sbjct: 1370 RNQATCVDELNSYSCKCQPGFS 1391
Score = 99 bits (238), Expect = 3e-20
Identities = 74/240 (30%), Positives = 107/240 (44%), Gaps = 32/240 (13%)
Query: 424 TQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGN 481
+Q EC P C G C + C CP GY GL C D DEC+ P + N
Sbjct: 1168 SQVFHECFFNP--CHNSGTCQQLGRGYVCLCPLGYT----GLKCETDIDECSPLPCL-NN 1220
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHNTAGSFRCTCPYGYA 540
G C + G + C+C G+T Q C + ++EC+ C + +RCTC G+
Sbjct: 1221 GVCKDLVGEFICECPSGYT---GQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFV 1277
Query: 541 VAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINEC 599
G+HC +++EC P + CE+ VG ++CKCP G+ T ++++EC
Sbjct: 1278 ----GLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGT-------RCGKNVDEC 1326
Query: 600 EEQEDLCSGGVCINTDGSFLCDCDAGFEPSE---DGTDCID---RRTGTCYRSLVSGRCE 653
Q +G C + SF C C AGF S + +C R TC L S C+
Sbjct: 1327 LSQ-PCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCK 1385
Score = 96.7 bits (230), Expect = 3e-19
Identities = 77/252 (30%), Positives = 113/252 (44%), Gaps = 34/252 (13%)
Query: 155 ECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGTCENLPGA 213
EC + G C+ Y C C GYT + C D+DECS P P NG C++L G
Sbjct: 1173 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLK--CETDIDECS-PLPCLNNGVCKDLVGE 1229
Query: 214 YLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR 273
++C C G+ + ++NEC + G C + V +RC C G+ G +C
Sbjct: 1230 FICECPSGYTGQRCEE--NINECSSSPCL-NKGICVDGVAGYRCTCVKGFV----GLHCE 1282
Query: 274 -DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCA-G 330
+V+EC +PC N C + GG+ C C G+ +G RC + DEC P C G
Sbjct: 1283 TEVNECQS--NPC--LNNAVCEDQVGGFLCKCPPGF--LGTRCGKNVDECLSQP--CKNG 1334
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPL--QLARPECC 388
C++ + C C AG+ T + C EL +E ++ C +L C
Sbjct: 1335 ATCKDGANSFRCLCAAGF----TGSHC-----ELNINECQSNPCRNQATCVDELNSYSCK 1385
Query: 389 CSEGAAWGRYCE 400
C G + G+ CE
Sbjct: 1386 CQPGFS-GKRCE 1396
Score = 96.7 bits (230), Expect = 3e-19
Identities = 67/222 (30%), Positives = 99/222 (44%), Gaps = 28/222 (12%)
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
++ +C G D+DEC P C+ G C + G F CECP GY G C +
Sbjct: 1192 YVCLCPLGYTGLKCETDIDECSPLP--CLNNGVCKDLVGEFICECPSGYT----GQRCEE 1245
Query: 469 -ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNT 527
+EC+ P + G C + GY C C GF +T +V+EC C +
Sbjct: 1246 NINECSSSPCL-NKGICVDGVAGYRCTCVKGFVGLHCET--EVNECQSNPCLNNAVCEDQ 1302
Query: 528 AGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAP 586
G F C CP G+ G C +++DEC+ +P C++ S+ C C G+
Sbjct: 1303 VGGFLCKCPPGFL----GTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGF------ 1352
Query: 587 QDSENACE-DINECEEQEDLCSG-GVCINTDGSFLCDCDAGF 626
+ + CE +INEC Q + C C++ S+ C C GF
Sbjct: 1353 --TGSHCELNINEC--QSNPCRNQATCVDELNSYSCKCQPGF 1390
Score = 92.7 bits (220), Expect = 5e-18
Identities = 57/175 (32%), Positives = 82/175 (46%), Gaps = 16/175 (9%)
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSC- 466
EF+ C G ++++EC P C+ G CV+ +RC C G+V GL C
Sbjct: 1229 EFICECPSGYTGQRCEENINECSSSP--CLNKGICVDGVAGYRCTCVKGFV----GLHCE 1282
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHN 526
+ +EC +P + N C + GG+ C+C PGF + +VDEC C +
Sbjct: 1283 TEVNECQSNPCL-NNAVCEDQVGGFLCKCPPGFLG--TRCGKNVDECLSQPCKNGATCKD 1339
Query: 527 TAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGY 580
A SFRC C G+ G HC +I+EC P C + + SY CKC G+
Sbjct: 1340 GANSFRCLCAAGFT----GSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGF 1390
Score = 82.2 bits (194), Expect = 7e-15
Identities = 68/232 (29%), Positives = 97/232 (41%), Gaps = 31/232 (13%)
Query: 283 HPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYV 341
+PC G +C GY C C G+ G +C D DEC LP + G C++ G ++
Sbjct: 1177 NPCHNSG--TCQQLGRGYVCLCPLGY--TGLKCETDIDECSPLPCL-NNGVCKDLVGEFI 1231
Query: 342 CECPAGW---RFDKTAAVCVDE---RKELCYDEWEAGRCHRARPLQLARPEC----CCSE 391
CECP+G+ R ++ C K +C D RC + E C S
Sbjct: 1232 CECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN 1291
Query: 392 GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFR 450
CE F+ C G +++DEC +P C G C + SFR
Sbjct: 1292 PCLNNAVCE----DQVGGFLCKCPPGFLGTRCGKNVDECLSQP--CKNGATCKDGANSFR 1345
Query: 451 CECPDGYVLAPDGLSC-VDADECALDPRICGN-GTCSNTRGGYECQCSPGFT 500
C C G+ G C ++ +EC +P C N TC + Y C+C PGF+
Sbjct: 1346 CLCAAGFT----GSHCELNINECQSNP--CRNQATCVDELNSYSCKCQPGFS 1391
Score = 61.7 bits (143), Expect = 1e-08
Identities = 56/220 (25%), Positives = 87/220 (39%), Gaps = 21/220 (9%)
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKEL-------CYDEWEAGRCHRARPLQLA 383
G C+ GYVC CP G+ K +DE L C D C
Sbjct: 1183 GTCQQLGRGYVCLCPLGYTGLK-CETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQ 1241
Query: 384 RPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-C 442
R E +E ++ + A + C G + +++EC+ P C+ C
Sbjct: 1242 RCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNP--CLNNAVC 1299
Query: 443 VNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNG-TCSNTRGGYECQCSPGFT 500
+ G F C+CP G++ G C + DEC P C NG TC + + C C+ GFT
Sbjct: 1300 EDQVGGFLCKCPPGFL----GTRCGKNVDECLSQP--CKNGATCKDGANSFRCLCAAGFT 1353
Query: 501 QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA 540
+ ++++EC C + S+ C C G++
Sbjct: 1354 GSHCE--LNINECQSNPCRNQATCVDELNSYSCKCQPGFS 1391
Score = 60.1 bits (139), Expect = 3e-08
Identities = 38/135 (28%), Positives = 54/135 (40%), Gaps = 6/135 (4%)
Query: 202 CRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAP 261
C NG C D+G G + C+DV+EC G + C N GS+ C C P
Sbjct: 1693 CNNGYYLLGDSRMFC-TDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVP 1751
Query: 262 GYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG---RRCVDR 318
Y T DG+NC + +C +P + SC G++L+G C++
Sbjct: 1752 PY--TGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLES 1809
Query: 319 DECKELPYVCAGGEC 333
E L C C
Sbjct: 1810 GEWNHLIPYCKAVSC 1824
Score = 58.0 bits (134), Expect = 1e-07
Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 14/113 (12%)
Query: 747 DVDECAAIPGL----CAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+V+EC + P L C G F C C PG+ G C +VDEC +P C +
Sbjct: 1284 EVNECQSNPCLNNAVCEDQVGGFLCKCPPGF--LGTRCGKNVDECLSQPCKNGATCKDGA 1341
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
S+ CLC G+ G++C +++EC+ + Q C + SY C C+ G+
Sbjct: 1342 NSFRCLCAAGF----TGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGF 1390
Score = 48.8 bits (111), Expect = 8e-05
Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 756 GLCAP-GR-FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G C GR + C+C GY G C D+DEC+ P + +C + G + C C +GY
Sbjct: 1183 GTCQQLGRGYVCLCPLGY--TGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGY-- 1238
Query: 813 DEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C + ++EC + IC + Y C+C G+
Sbjct: 1239 --TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGF 1276
Score = 47.6 bits (108), Expect = 2e-04
Identities = 32/105 (30%), Positives = 44/105 (41%), Gaps = 9/105 (8%)
Query: 757 LCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDED 815
L R C + C DVDECAV + C N DGSY C C Y D
Sbjct: 1699 LLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPY--TGD 1756
Query: 816 GANCRDVDECE-----RDTHTCQQICSNTEGSYECSCEDGYEKRG 855
G NC + +C+ + H+ +I + SC++GY+ G
Sbjct: 1757 GKNCAEPIKCKAPGNPENGHSSGEIYT-VGAEVTFSCQEGYQLMG 1800
Score = 45.2 bits (102), Expect = 0.001
Identities = 21/50 (42%), Positives = 24/50 (48%), Gaps = 1/50 (2%)
Query: 150 CEDVDECGDQRIC-DHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRP 198
C DVDEC C +H C N GSY C C P YT C + +C P
Sbjct: 1720 CLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAP 1769
Score = 44.8 bits (101), Expect = 0.001
Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Query: 447 GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT 506
G R C D SC+D DECA+ + +C N G Y C C P +T G +
Sbjct: 1701 GDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYT-GDGKN 1759
Query: 507 CVDVDEC 513
C + +C
Sbjct: 1760 CAEPIKC 1766
Score = 44.8 bits (101), Expect = 0.001
Identities = 33/121 (27%), Positives = 50/121 (41%), Gaps = 10/121 (8%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C + S C DVDEC+ G C A C+N+ G++ C C P Y T C +
Sbjct: 1707 CTDNGSWNGVSPSCLDVDECAVGSD-CSEHASCLNVDGSYICSCVPPY--TGDGKNCAEP 1763
Query: 154 DECGDQRICDHGDCRNTIGSYRCE----CKPGYTL---RENVCRDVDECSRPRPVCRNGT 206
+C ++G I + E C+ GY L + C + E + P C+ +
Sbjct: 1764 IKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVS 1823
Query: 207 C 207
C
Sbjct: 1824 C 1824
Score = 44.4 bits (100), Expect = 0.002
Identities = 47/174 (27%), Positives = 68/174 (39%), Gaps = 25/174 (14%)
Query: 189 CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC 248
C DVDEC+ + +C N+ G+Y+C C + G +C + +C+ G NG
Sbjct: 1720 CLDVDECAVGSDCSEHASCLNVDGSYICSCVPPY-TGDGKNCAEPIKCKAPGNP-ENGHS 1777
Query: 249 RN---TVGS-FRCECAPGYTLTADGR-NCRDVDECDEL-PH----PCGRDGNP--SCTN- 295
TVG+ C GY L + C + E + L P+ CG+ P C
Sbjct: 1778 SGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEE 1837
Query: 296 ---TNGG-YECSCGAGWKLVGRR---CVDRDECKELPYVCAGGEC---RNFNGG 339
T G C G+ L G + C+ P VC +C N N G
Sbjct: 1838 LAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNG 1891
Score = 41.1 bits (92), Expect = 0.016
Identities = 22/70 (31%), Positives = 26/70 (37%), Gaps = 5/70 (7%)
Query: 783 ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEG 841
EC P C Y CLC GY G C D+DEC +C + G
Sbjct: 1173 ECFFNPCHNSGTCQQLGRGYVCLCPLGY----TGLKCETDIDECSPLPCLNNGVCKDLVG 1228
Query: 842 SYECSCEDGY 851
+ C C GY
Sbjct: 1229 EFICECPSGY 1238
Score = 40.7 bits (91), Expect = 0.022
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC 472
D+DEC V D C+N DGS+ C C Y DG +C + +C
Sbjct: 1722 DVDECAVGSDCSEHASCLNVDGSYICSCVPPY--TGDGKNCAEPIKC 1766
Score = 40.3 bits (90), Expect = 0.028
Identities = 33/117 (28%), Positives = 46/117 (39%), Gaps = 13/117 (11%)
Query: 518 ASCTFRCHN---TAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYI 573
++ T++C+N G R C + C D+DEC HA C NV GSYI
Sbjct: 1687 STVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYI 1746
Query: 574 CKCPEGYRRTSAPQDSENACEDINECE---EQEDLCSGGVCINTDGSFLCDCDAGFE 627
C C Y D +N E I +C+ E+ S G C G++
Sbjct: 1747 CSCVPPY-----TGDGKNCAEPI-KCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQ 1797
Score = 39.9 bits (89), Expect = 0.038
Identities = 22/59 (37%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 498 GFTQGPDQTCVDVDECAEGRASCT--FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDEC 554
G G +C+DVDECA G + C+ C N GS+ C+C Y DG +C + +C
Sbjct: 1711 GSWNGVSPSCLDVDECAVG-SDCSEHASCLNVDGSYICSCVPPY--TGDGKNCAEPIKC 1766
Score = 39.1 bits (87), Expect = 0.066
Identities = 15/46 (32%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
+C D++EC D C+N DGS++C C + + DG +C +
Sbjct: 1719 SCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPY--TGDGKNCAE 1762
Score = 38.3 bits (85), Expect = 0.11
Identities = 51/194 (26%), Positives = 70/194 (36%), Gaps = 43/194 (22%)
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSY----RCECKPGYTLR---ENVC 189
C P T + +CE + CG ++ R Y C GY L +VC
Sbjct: 3375 CNPDETWTQTSAKCEKIS-CGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVC 3433
Query: 190 RDVDECSRP---RPVCR-----NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGM 241
+ + P R VCR G C+ P A C C +G+ + + + C GG
Sbjct: 3434 LENGTWTSPPICRAVCRFPCQNGGICQR-PNA--CSCPEGWMGRLCEEPICILPCLNGG- 3489
Query: 242 VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYE 301
RC V ++C+C PG+T G C C PC G C N
Sbjct: 3490 -----RC---VAPYQCDCPPGWT----GSRCHTA-VCQS---PCLNGG--KCVRPN---R 3528
Query: 302 CSCGAGWKLVGRRC 315
C C + W G C
Sbjct: 3529 CHCLSSW--TGHNC 3540
Score = 36.7 bits (81), Expect = 0.35
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 818 NCRDVDECERDTHTCQQI-CSNTEGSYECSCEDGYEKRGDAC 858
+C DVDEC + + C N +GSY CSC Y G C
Sbjct: 1719 SCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNC 1760
Score = 35.9 bits (79), Expect = 0.61
Identities = 14/43 (32%), Positives = 18/43 (41%)
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCEC 344
C+ W V C+D DEC C N +G Y+C C
Sbjct: 1707 CTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSC 1749
Score = 34.7 bits (76), Expect = 1.4
Identities = 34/106 (32%), Positives = 40/106 (37%), Gaps = 24/106 (22%)
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCE 343
PC G C N CSC GW +GR C + C LP + GG C Y C+
Sbjct: 3452 PCQNGG--ICQRPNA---CSCPEGW--MGRLC-EEPICI-LPCL-NGGRCV---APYQCD 3498
Query: 344 CPAGWRFDK--TAAV---------CVDERKELCYDEWEAGRCHRAR 378
CP GW + TA CV + C W C R R
Sbjct: 3499 CPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNCSRKR 3544
Score = 33.1 bits (72), Expect = 4.3
Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 3/53 (5%)
Query: 755 PGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNT-DGSYDCLC 806
PG +P CVC GYR +G+ C V A++PP NT + ++ C
Sbjct: 329 PGSTSPED--CVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAAC 379
Score = 32.3 bits (70), Expect = 7.5
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 14/88 (15%)
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPG 498
GG C + C CP+G++ G C + C L C NG Y+C C PG
Sbjct: 3456 GGICQRPNA---CSCPEGWM----GRLC-EEPICILP---CLNG--GRCVAPYQCDCPPG 3502
Query: 499 FTQGPDQTCVDVDECAE-GRASCTFRCH 525
+T T V C G+ RCH
Sbjct: 3503 WTGSRCHTAVCQSPCLNGGKCVRPNRCH 3530
>AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens cDNA
FLJ14964 fis, clone PLACE4000581, moderately similar to
FIBROPELLIN I PRECURSOR. ).
Length = 1316
Score = 122 bits (293), Expect = 7e-27
Identities = 82/241 (34%), Positives = 114/241 (47%), Gaps = 34/241 (14%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
GTC G+ C C GY T C D+DECS PC C +L G F C CP
Sbjct: 973 GTCQQLGRGYVCLCPLGY----TGLKCETDIDECS--PLPCLNNGVCKDLVGEFICECPS 1026
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPR 199
GY T E E+++EC + G C + + YRC C G+ + + +V+EC +
Sbjct: 1027 GY--TGQRCE-ENINECSSSPCLNKGICVDGVAGYRCTCVKGF-VGLHCETEVNEC-QSN 1081
Query: 200 PVCRNGTCENLPGAYLCHCDDGF---KAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSF 255
P N CE+ G +LC C GF + G N V+EC C+NG C++ SF
Sbjct: 1082 PCLNNAVCEDQVGGFLCKCPPGFLGTRCGKN-----VDECL--SQPCKNGATCKDGANSF 1134
Query: 256 RCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR 314
RC CA G+T G +C +++EC +PC +C + Y C C G+ G+R
Sbjct: 1135 RCLCAAGFT----GSHCELNINECQS--NPCRNQA--TCVDELNSYSCKCQPGFS--GKR 1184
Query: 315 C 315
C
Sbjct: 1185 C 1185
Score = 117 bits (281), Expect = 2e-25
Identities = 76/233 (32%), Positives = 112/233 (48%), Gaps = 23/233 (9%)
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCE 177
PC C L + C CP GY +CE D+DEC ++G C++ +G + CE
Sbjct: 968 PCHNSGTCQQLGRGYVCLCPLGYTGL----KCETDIDECSPLPCLNNGVCKDLVGEFICE 1023
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECR 237
C GYT + +++ECS P G C + Y C C GF G + + +VNEC+
Sbjct: 1024 CPSGYT-GQRCEENINECS-SSPCLNKGICVDGVAGYRCTCVKGF-VGLHCE-TEVNECQ 1079
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTN 297
+ N C + VG F C+C PG+ T G+N VDEC L PC ++G +C +
Sbjct: 1080 SNPCL-NNAVCEDQVGGFLCKCPPGFLGTRCGKN---VDEC--LSQPC-KNG-ATCKDGA 1131
Query: 298 GGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECRNFNGGYVCECPAGW 348
+ C C AG+ G C ++ +EC+ P C C + Y C+C G+
Sbjct: 1132 NSFRCLCAAGF--TGSHCELNINECQSNP--CRNQATCVDELNSYSCKCQPGF 1180
Score = 101 bits (241), Expect = 1e-20
Identities = 67/202 (33%), Positives = 103/202 (50%), Gaps = 24/202 (11%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD-VDECSWGRPPCRGMAQC 126
IDEC +P L G C D F C C GY T C + ++ECS PC C
Sbjct: 999 IDECSPLPCL-NNGVCKDLVGEFICECPSGY----TGQRCEENINECS--SSPCLNKGIC 1051
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
V+ + C C G+ L CE +V+EC ++ C + +G + C+C PG+ L
Sbjct: 1052 VDGVAGYRCTCVKGF---VGL-HCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGF-LG 1106
Query: 186 ENVCRDVDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC 243
++VDEC S+P C+NG TC++ ++ C C GF G + + +++NEC+ C
Sbjct: 1107 TRCGKNVDECLSQP---CKNGATCKDGANSFRCLCAAGF-TGSHCE-LNINECQSNP--C 1159
Query: 244 RN-GRCRNTVGSFRCECAPGYT 264
RN C + + S+ C+C PG++
Sbjct: 1160 RNQATCVDELNSYSCKCQPGFS 1181
Score = 99 bits (238), Expect = 3e-20
Identities = 74/240 (30%), Positives = 107/240 (44%), Gaps = 32/240 (13%)
Query: 424 TQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGN 481
+Q EC P C G C + C CP GY GL C D DEC+ P + N
Sbjct: 958 SQVFHECFFNP--CHNSGTCQQLGRGYVCLCPLGYT----GLKCETDIDECSPLPCL-NN 1010
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHNTAGSFRCTCPYGYA 540
G C + G + C+C G+T Q C + ++EC+ C + +RCTC G+
Sbjct: 1011 GVCKDLVGEFICECPSGYT---GQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFV 1067
Query: 541 VAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINEC 599
G+HC +++EC P + CE+ VG ++CKCP G+ T ++++EC
Sbjct: 1068 ----GLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGT-------RCGKNVDEC 1116
Query: 600 EEQEDLCSGGVCINTDGSFLCDCDAGFEPSE---DGTDCID---RRTGTCYRSLVSGRCE 653
Q +G C + SF C C AGF S + +C R TC L S C+
Sbjct: 1117 LSQ-PCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCK 1175
Score = 96.7 bits (230), Expect = 3e-19
Identities = 77/252 (30%), Positives = 113/252 (44%), Gaps = 34/252 (13%)
Query: 155 ECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGTCENLPGA 213
EC + G C+ Y C C GYT + C D+DECS P P NG C++L G
Sbjct: 963 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLK--CETDIDECS-PLPCLNNGVCKDLVGE 1019
Query: 214 YLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR 273
++C C G+ + ++NEC + G C + V +RC C G+ G +C
Sbjct: 1020 FICECPSGYTGQRCEE--NINECSSSPCL-NKGICVDGVAGYRCTCVKGFV----GLHCE 1072
Query: 274 -DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCA-G 330
+V+EC +PC N C + GG+ C C G+ +G RC + DEC P C G
Sbjct: 1073 TEVNECQS--NPC--LNNAVCEDQVGGFLCKCPPGF--LGTRCGKNVDECLSQP--CKNG 1124
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPL--QLARPECC 388
C++ + C C AG+ T + C EL +E ++ C +L C
Sbjct: 1125 ATCKDGANSFRCLCAAGF----TGSHC-----ELNINECQSNPCRNQATCVDELNSYSCK 1175
Query: 389 CSEGAAWGRYCE 400
C G + G+ CE
Sbjct: 1176 CQPGFS-GKRCE 1186
Score = 96.7 bits (230), Expect = 3e-19
Identities = 67/222 (30%), Positives = 99/222 (44%), Gaps = 28/222 (12%)
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
++ +C G D+DEC P C+ G C + G F CECP GY G C +
Sbjct: 982 YVCLCPLGYTGLKCETDIDECSPLP--CLNNGVCKDLVGEFICECPSGYT----GQRCEE 1035
Query: 469 -ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNT 527
+EC+ P + G C + GY C C GF +T +V+EC C +
Sbjct: 1036 NINECSSSPCL-NKGICVDGVAGYRCTCVKGFVGLHCET--EVNECQSNPCLNNAVCEDQ 1092
Query: 528 AGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAP 586
G F C CP G+ G C +++DEC+ +P C++ S+ C C G+
Sbjct: 1093 VGGFLCKCPPGFL----GTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGF------ 1142
Query: 587 QDSENACE-DINECEEQEDLCSG-GVCINTDGSFLCDCDAGF 626
+ + CE +INEC Q + C C++ S+ C C GF
Sbjct: 1143 --TGSHCELNINEC--QSNPCRNQATCVDELNSYSCKCQPGF 1180
Score = 92.7 bits (220), Expect = 5e-18
Identities = 57/175 (32%), Positives = 82/175 (46%), Gaps = 16/175 (9%)
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSC- 466
EF+ C G ++++EC P C+ G CV+ +RC C G+V GL C
Sbjct: 1019 EFICECPSGYTGQRCEENINECSSSP--CLNKGICVDGVAGYRCTCVKGFV----GLHCE 1072
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHN 526
+ +EC +P + N C + GG+ C+C PGF + +VDEC C +
Sbjct: 1073 TEVNECQSNPCL-NNAVCEDQVGGFLCKCPPGFLG--TRCGKNVDECLSQPCKNGATCKD 1129
Query: 527 TAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGY 580
A SFRC C G+ G HC +I+EC P C + + SY CKC G+
Sbjct: 1130 GANSFRCLCAAGFT----GSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGF 1180
Score = 82.2 bits (194), Expect = 7e-15
Identities = 68/232 (29%), Positives = 97/232 (41%), Gaps = 31/232 (13%)
Query: 283 HPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYV 341
+PC G +C GY C C G+ G +C D DEC LP + G C++ G ++
Sbjct: 967 NPCHNSG--TCQQLGRGYVCLCPLGY--TGLKCETDIDECSPLPCL-NNGVCKDLVGEFI 1021
Query: 342 CECPAGW---RFDKTAAVCVDE---RKELCYDEWEAGRCHRARPLQLARPEC----CCSE 391
CECP+G+ R ++ C K +C D RC + E C S
Sbjct: 1022 CECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN 1081
Query: 392 GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFR 450
CE F+ C G +++DEC +P C G C + SFR
Sbjct: 1082 PCLNNAVCE----DQVGGFLCKCPPGFLGTRCGKNVDECLSQP--CKNGATCKDGANSFR 1135
Query: 451 CECPDGYVLAPDGLSC-VDADECALDPRICGN-GTCSNTRGGYECQCSPGFT 500
C C G+ G C ++ +EC +P C N TC + Y C+C PGF+
Sbjct: 1136 CLCAAGFT----GSHCELNINECQSNP--CRNQATCVDELNSYSCKCQPGFS 1181
Score = 61.7 bits (143), Expect = 1e-08
Identities = 56/220 (25%), Positives = 87/220 (39%), Gaps = 21/220 (9%)
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKEL-------CYDEWEAGRCHRARPLQLA 383
G C+ GYVC CP G+ K +DE L C D C
Sbjct: 973 GTCQQLGRGYVCLCPLGYTGLK-CETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQ 1031
Query: 384 RPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-C 442
R E +E ++ + A + C G + +++EC+ P C+ C
Sbjct: 1032 RCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNP--CLNNAVC 1089
Query: 443 VNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNG-TCSNTRGGYECQCSPGFT 500
+ G F C+CP G++ G C + DEC P C NG TC + + C C+ GFT
Sbjct: 1090 EDQVGGFLCKCPPGFL----GTRCGKNVDECLSQP--CKNGATCKDGANSFRCLCAAGFT 1143
Query: 501 QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA 540
+ ++++EC C + S+ C C G++
Sbjct: 1144 GSHCE--LNINECQSNPCRNQATCVDELNSYSCKCQPGFS 1181
Score = 58.0 bits (134), Expect = 1e-07
Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 14/113 (12%)
Query: 747 DVDECAAIPGL----CAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+V+EC + P L C G F C C PG+ G C +VDEC +P C +
Sbjct: 1074 EVNECQSNPCLNNAVCEDQVGGFLCKCPPGF--LGTRCGKNVDECLSQPCKNGATCKDGA 1131
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
S+ CLC G+ G++C +++EC+ + Q C + SY C C+ G+
Sbjct: 1132 NSFRCLCAAGF----TGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGF 1180
Score = 48.8 bits (111), Expect = 8e-05
Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 756 GLCAP-GR-FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G C GR + C+C GY G C D+DEC+ P + +C + G + C C +GY
Sbjct: 973 GTCQQLGRGYVCLCPLGY--TGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGY-- 1028
Query: 813 DEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C + ++EC + IC + Y C+C G+
Sbjct: 1029 --TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGF 1066
Score = 41.1 bits (92), Expect = 0.016
Identities = 22/70 (31%), Positives = 26/70 (37%), Gaps = 5/70 (7%)
Query: 783 ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEG 841
EC P C Y CLC GY G C D+DEC +C + G
Sbjct: 963 ECFFNPCHNSGTCQQLGRGYVCLCPLGY----TGLKCETDIDECSPLPCLNNGVCKDLVG 1018
Query: 842 SYECSCEDGY 851
+ C C GY
Sbjct: 1019 EFICECPSGY 1028
Score = 33.1 bits (72), Expect = 4.3
Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 3/53 (5%)
Query: 755 PGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNT-DGSYDCLC 806
PG +P CVC GYR +G+ C V A++PP NT + ++ C
Sbjct: 119 PGSTSPED--CVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAAC 169
>AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein.
Length = 3574
Score = 122 bits (293), Expect = 7e-27
Identities = 82/241 (34%), Positives = 114/241 (47%), Gaps = 34/241 (14%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
GTC G+ C C GY T C D+DECS PC C +L G F C CP
Sbjct: 1206 GTCQQLGRGYVCLCPLGY----TGLKCETDIDECS--PLPCLNNGVCKDLVGEFICECPS 1259
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPR 199
GY T E E+++EC + G C + + YRC C G+ + + +V+EC +
Sbjct: 1260 GY--TGQRCE-ENINECSSSPCLNKGICVDGVAGYRCTCVKGF-VGLHCETEVNEC-QSN 1314
Query: 200 PVCRNGTCENLPGAYLCHCDDGF---KAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSF 255
P N CE+ G +LC C GF + G N V+EC C+NG C++ SF
Sbjct: 1315 PCLNNAVCEDQVGGFLCKCPPGFLGTRCGKN-----VDECL--SQPCKNGATCKDGANSF 1367
Query: 256 RCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR 314
RC CA G+T G +C +++EC +PC +C + Y C C G+ G+R
Sbjct: 1368 RCLCAAGFT----GSHCELNINECQS--NPCRNQA--TCVDELNSYSCKCQPGFS--GKR 1417
Query: 315 C 315
C
Sbjct: 1418 C 1418
Score = 117 bits (281), Expect = 2e-25
Identities = 76/233 (32%), Positives = 112/233 (48%), Gaps = 23/233 (9%)
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCE 177
PC C L + C CP GY +CE D+DEC ++G C++ +G + CE
Sbjct: 1201 PCHNSGTCQQLGRGYVCLCPLGYTGL----KCETDIDECSPLPCLNNGVCKDLVGEFICE 1256
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECR 237
C GYT + +++ECS P G C + Y C C GF G + + +VNEC+
Sbjct: 1257 CPSGYT-GQRCEENINECS-SSPCLNKGICVDGVAGYRCTCVKGF-VGLHCE-TEVNECQ 1312
Query: 238 EGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTN 297
+ N C + VG F C+C PG+ T G+N VDEC L PC ++G +C +
Sbjct: 1313 SNPCL-NNAVCEDQVGGFLCKCPPGFLGTRCGKN---VDEC--LSQPC-KNG-ATCKDGA 1364
Query: 298 GGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECRNFNGGYVCECPAGW 348
+ C C AG+ G C ++ +EC+ P C C + Y C+C G+
Sbjct: 1365 NSFRCLCAAGF--TGSHCELNINECQSNP--CRNQATCVDELNSYSCKCQPGF 1413
Score = 101 bits (241), Expect = 1e-20
Identities = 67/202 (33%), Positives = 103/202 (50%), Gaps = 24/202 (11%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRD-VDECSWGRPPCRGMAQC 126
IDEC +P L G C D F C C GY T C + ++ECS PC C
Sbjct: 1232 IDECSPLPCL-NNGVCKDLVGEFICECPSGY----TGQRCEENINECS--SSPCLNKGIC 1284
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
V+ + C C G+ L CE +V+EC ++ C + +G + C+C PG+ L
Sbjct: 1285 VDGVAGYRCTCVKGF---VGL-HCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGF-LG 1339
Query: 186 ENVCRDVDEC-SRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVC 243
++VDEC S+P C+NG TC++ ++ C C GF G + + +++NEC+ C
Sbjct: 1340 TRCGKNVDECLSQP---CKNGATCKDGANSFRCLCAAGF-TGSHCE-LNINECQSNP--C 1392
Query: 244 RN-GRCRNTVGSFRCECAPGYT 264
RN C + + S+ C+C PG++
Sbjct: 1393 RNQATCVDELNSYSCKCQPGFS 1414
Score = 99 bits (238), Expect = 3e-20
Identities = 74/240 (30%), Positives = 107/240 (44%), Gaps = 32/240 (13%)
Query: 424 TQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGN 481
+Q EC P C G C + C CP GY GL C D DEC+ P + N
Sbjct: 1191 SQVFHECFFNP--CHNSGTCQQLGRGYVCLCPLGYT----GLKCETDIDECSPLPCL-NN 1243
Query: 482 GTCSNTRGGYECQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHNTAGSFRCTCPYGYA 540
G C + G + C+C G+T Q C + ++EC+ C + +RCTC G+
Sbjct: 1244 GVCKDLVGEFICECPSGYT---GQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFV 1300
Query: 541 VAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINEC 599
G+HC +++EC P + CE+ VG ++CKCP G+ T ++++EC
Sbjct: 1301 ----GLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGT-------RCGKNVDEC 1349
Query: 600 EEQEDLCSGGVCINTDGSFLCDCDAGFEPSE---DGTDCID---RRTGTCYRSLVSGRCE 653
Q +G C + SF C C AGF S + +C R TC L S C+
Sbjct: 1350 LSQ-PCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCK 1408
Score = 96.7 bits (230), Expect = 3e-19
Identities = 77/252 (30%), Positives = 113/252 (44%), Gaps = 34/252 (13%)
Query: 155 ECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCR-DVDECSRPRPVCRNGTCENLPGA 213
EC + G C+ Y C C GYT + C D+DECS P P NG C++L G
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLK--CETDIDECS-PLPCLNNGVCKDLVGE 1252
Query: 214 YLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR 273
++C C G+ + ++NEC + G C + V +RC C G+ G +C
Sbjct: 1253 FICECPSGYTGQRCEE--NINECSSSPCL-NKGICVDGVAGYRCTCVKGFV----GLHCE 1305
Query: 274 -DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCA-G 330
+V+EC +PC N C + GG+ C C G+ +G RC + DEC P C G
Sbjct: 1306 TEVNECQS--NPC--LNNAVCEDQVGGFLCKCPPGF--LGTRCGKNVDECLSQP--CKNG 1357
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPL--QLARPECC 388
C++ + C C AG+ T + C EL +E ++ C +L C
Sbjct: 1358 ATCKDGANSFRCLCAAGF----TGSHC-----ELNINECQSNPCRNQATCVDELNSYSCK 1408
Query: 389 CSEGAAWGRYCE 400
C G + G+ CE
Sbjct: 1409 CQPGFS-GKRCE 1419
Score = 96.7 bits (230), Expect = 3e-19
Identities = 67/222 (30%), Positives = 99/222 (44%), Gaps = 28/222 (12%)
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
++ +C G D+DEC P C+ G C + G F CECP GY G C +
Sbjct: 1215 YVCLCPLGYTGLKCETDIDECSPLP--CLNNGVCKDLVGEFICECPSGYT----GQRCEE 1268
Query: 469 -ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNT 527
+EC+ P + G C + GY C C GF +T +V+EC C +
Sbjct: 1269 NINECSSSPCL-NKGICVDGVAGYRCTCVKGFVGLHCET--EVNECQSNPCLNNAVCEDQ 1325
Query: 528 AGSFRCTCPYGYAVAADGVHC-RDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAP 586
G F C CP G+ G C +++DEC+ +P C++ S+ C C G+
Sbjct: 1326 VGGFLCKCPPGFL----GTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGF------ 1375
Query: 587 QDSENACE-DINECEEQEDLCSG-GVCINTDGSFLCDCDAGF 626
+ + CE +INEC Q + C C++ S+ C C GF
Sbjct: 1376 --TGSHCELNINEC--QSNPCRNQATCVDELNSYSCKCQPGF 1413
Score = 92.7 bits (220), Expect = 5e-18
Identities = 57/175 (32%), Positives = 82/175 (46%), Gaps = 16/175 (9%)
Query: 409 EFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSC- 466
EF+ C G ++++EC P C+ G CV+ +RC C G+V GL C
Sbjct: 1252 EFICECPSGYTGQRCEENINECSSSP--CLNKGICVDGVAGYRCTCVKGFV----GLHCE 1305
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHN 526
+ +EC +P + N C + GG+ C+C PGF + +VDEC C +
Sbjct: 1306 TEVNECQSNPCL-NNAVCEDQVGGFLCKCPPGFLG--TRCGKNVDECLSQPCKNGATCKD 1362
Query: 527 TAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGY 580
A SFRC C G+ G HC +I+EC P C + + SY CKC G+
Sbjct: 1363 GANSFRCLCAAGFT----GSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGF 1413
Score = 82.2 bits (194), Expect = 7e-15
Identities = 68/232 (29%), Positives = 97/232 (41%), Gaps = 31/232 (13%)
Query: 283 HPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGGECRNFNGGYV 341
+PC G +C GY C C G+ G +C D DEC LP + G C++ G ++
Sbjct: 1200 NPCHNSG--TCQQLGRGYVCLCPLGY--TGLKCETDIDECSPLPCL-NNGVCKDLVGEFI 1254
Query: 342 CECPAGW---RFDKTAAVCVDE---RKELCYDEWEAGRCHRARPLQLARPEC----CCSE 391
CECP+G+ R ++ C K +C D RC + E C S
Sbjct: 1255 CECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN 1314
Query: 392 GAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFR 450
CE F+ C G +++DEC +P C G C + SFR
Sbjct: 1315 PCLNNAVCE----DQVGGFLCKCPPGFLGTRCGKNVDECLSQP--CKNGATCKDGANSFR 1368
Query: 451 CECPDGYVLAPDGLSC-VDADECALDPRICGN-GTCSNTRGGYECQCSPGFT 500
C C G+ G C ++ +EC +P C N TC + Y C+C PGF+
Sbjct: 1369 CLCAAGFT----GSHCELNINECQSNP--CRNQATCVDELNSYSCKCQPGFS 1414
Score = 61.7 bits (143), Expect = 1e-08
Identities = 56/220 (25%), Positives = 87/220 (39%), Gaps = 21/220 (9%)
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKEL-------CYDEWEAGRCHRARPLQLA 383
G C+ GYVC CP G+ K +DE L C D C
Sbjct: 1206 GTCQQLGRGYVCLCPLGYTGLK-CETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQ 1264
Query: 384 RPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-C 442
R E +E ++ + A + C G + +++EC+ P C+ C
Sbjct: 1265 RCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNP--CLNNAVC 1322
Query: 443 VNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNG-TCSNTRGGYECQCSPGFT 500
+ G F C+CP G++ G C + DEC P C NG TC + + C C+ GFT
Sbjct: 1323 EDQVGGFLCKCPPGFL----GTRCGKNVDECLSQP--CKNGATCKDGANSFRCLCAAGFT 1376
Query: 501 QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYA 540
+ ++++EC C + S+ C C G++
Sbjct: 1377 GSHCE--LNINECQSNPCRNQATCVDELNSYSCKCQPGFS 1414
Score = 60.9 bits (141), Expect = 2e-08
Identities = 38/135 (28%), Positives = 54/135 (40%), Gaps = 6/135 (4%)
Query: 202 CRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAP 261
C NG C D+G G + C+DV+EC G + C N GS+ C C P
Sbjct: 1719 CNNGYYLLGDSRMFC-TDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVP 1777
Query: 262 GYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG---RRCVDR 318
Y T DG+NC + +C +P + SC G++L+G C++
Sbjct: 1778 SY--TGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLES 1835
Query: 319 DECKELPYVCAGGEC 333
E L C C
Sbjct: 1836 GEWNHLIPYCKAVSC 1850
Score = 58.0 bits (134), Expect = 1e-07
Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 14/113 (12%)
Query: 747 DVDECAAIPGL----CAP--GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
+V+EC + P L C G F C C PG+ G C +VDEC +P C +
Sbjct: 1307 EVNECQSNPCLNNAVCEDQVGGFLCKCPPGF--LGTRCGKNVDECLSQPCKNGATCKDGA 1364
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
S+ CLC G+ G++C +++EC+ + Q C + SY C C+ G+
Sbjct: 1365 NSFRCLCAAGF----TGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGF 1413
Score = 48.8 bits (111), Expect = 8e-05
Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 756 GLCAP-GR-FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G C GR + C+C GY G C D+DEC+ P + +C + G + C C +GY
Sbjct: 1206 GTCQQLGRGYVCLCPLGY--TGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGY-- 1261
Query: 813 DEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
G C + ++EC + IC + Y C+C G+
Sbjct: 1262 --TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGF 1299
Score = 48.4 bits (110), Expect = 1e-04
Identities = 32/105 (30%), Positives = 44/105 (41%), Gaps = 9/105 (8%)
Query: 757 LCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDED 815
L R C + C DVDECAV + C N DGSY C C Y D
Sbjct: 1725 LLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPSY--TGD 1782
Query: 816 GANCRDVDECE-----RDTHTCQQICSNTEGSYECSCEDGYEKRG 855
G NC + +C+ + H+ +I + SC++GY+ G
Sbjct: 1783 GKNCAEPIKCKAPGNPENGHSSGEIYT-VGAEVTFSCQEGYQLMG 1826
Score = 46.0 bits (104), Expect = 6e-04
Identities = 21/50 (42%), Positives = 24/50 (48%), Gaps = 1/50 (2%)
Query: 150 CEDVDECGDQRIC-DHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRP 198
C DVDEC C +H C N GSY C C P YT C + +C P
Sbjct: 1746 CLDVDECAVGSDCSEHASCLNVDGSYICSCVPSYTGDGKNCAEPIKCKAP 1795
Score = 45.6 bits (103), Expect = 8e-04
Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Query: 447 GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT 506
G R C D SC+D DECA+ + +C N G Y C C P +T G +
Sbjct: 1727 GDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPSYT-GDGKN 1785
Query: 507 CVDVDEC 513
C + +C
Sbjct: 1786 CAEPIKC 1792
Score = 45.6 bits (103), Expect = 8e-04
Identities = 33/121 (27%), Positives = 50/121 (41%), Gaps = 10/121 (8%)
Query: 94 CDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
C + S C DVDEC+ G C A C+N+ G++ C C P Y T C +
Sbjct: 1733 CTDNGSWNGVSPSCLDVDECAVGSD-CSEHASCLNVDGSYICSCVPSY--TGDGKNCAEP 1789
Query: 154 DECGDQRICDHGDCRNTIGSYRCE----CKPGYTL---RENVCRDVDECSRPRPVCRNGT 206
+C ++G I + E C+ GY L + C + E + P C+ +
Sbjct: 1790 IKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVS 1849
Query: 207 C 207
C
Sbjct: 1850 C 1850
Score = 45.2 bits (102), Expect = 0.001
Identities = 47/174 (27%), Positives = 68/174 (39%), Gaps = 25/174 (14%)
Query: 189 CRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC 248
C DVDEC+ + +C N+ G+Y+C C + G +C + +C+ G NG
Sbjct: 1746 CLDVDECAVGSDCSEHASCLNVDGSYICSCVPSY-TGDGKNCAEPIKCKAPGNP-ENGHS 1803
Query: 249 RN---TVGS-FRCECAPGYTLTADGR-NCRDVDECDEL-PH----PCGRDGNP--SCTN- 295
TVG+ C GY L + C + E + L P+ CG+ P C
Sbjct: 1804 SGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEE 1863
Query: 296 ---TNGG-YECSCGAGWKLVGRR---CVDRDECKELPYVCAGGEC---RNFNGG 339
T G C G+ L G + C+ P VC +C N N G
Sbjct: 1864 LAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNG 1917
Score = 41.5 bits (93), Expect = 0.012
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADEC 472
D+DEC V D C+N DGS+ C C Y DG +C + +C
Sbjct: 1748 DVDECAVGSDCSEHASCLNVDGSYICSCVPSY--TGDGKNCAEPIKC 1792
Score = 41.1 bits (92), Expect = 0.016
Identities = 22/70 (31%), Positives = 26/70 (37%), Gaps = 5/70 (7%)
Query: 783 ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEG 841
EC P C Y CLC GY G C D+DEC +C + G
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGY----TGLKCETDIDECSPLPCLNNGVCKDLVG 1251
Query: 842 SYECSCEDGY 851
+ C C GY
Sbjct: 1252 EFICECPSGY 1261
Score = 41.1 bits (92), Expect = 0.016
Identities = 33/117 (28%), Positives = 46/117 (39%), Gaps = 13/117 (11%)
Query: 518 ASCTFRCHN---TAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA-CENVVGSYI 573
++ T++C+N G R C + C D+DEC HA C NV GSYI
Sbjct: 1713 STVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYI 1772
Query: 574 CKCPEGYRRTSAPQDSENACEDINECE---EQEDLCSGGVCINTDGSFLCDCDAGFE 627
C C Y D +N E I +C+ E+ S G C G++
Sbjct: 1773 CSCVPSY-----TGDGKNCAEPI-KCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQ 1823
Score = 40.7 bits (91), Expect = 0.022
Identities = 22/59 (37%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 498 GFTQGPDQTCVDVDECAEGRASCT--FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDEC 554
G G +C+DVDECA G + C+ C N GS+ C+C Y DG +C + +C
Sbjct: 1737 GSWNGVSPSCLDVDECAVG-SDCSEHASCLNVDGSYICSCVPSY--TGDGKNCAEPIKC 1792
Score = 39.9 bits (89), Expect = 0.038
Identities = 15/46 (32%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 592 ACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
+C D++EC D C+N DGS++C C + + DG +C +
Sbjct: 1745 SCLDVDECAVGSDCSEHASCLNVDGSYICSCVPSY--TGDGKNCAE 1788
Score = 37.5 bits (83), Expect = 0.20
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 818 NCRDVDECERDTHTCQQI-CSNTEGSYECSCEDGYEKRGDAC 858
+C DVDEC + + C N +GSY CSC Y G C
Sbjct: 1745 SCLDVDECAVGSDCSEHASCLNVDGSYICSCVPSYTGDGKNC 1786
Score = 36.3 bits (80), Expect = 0.46
Identities = 15/50 (30%), Positives = 20/50 (40%)
Query: 302 CSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFD 351
C+ W V C+D DEC C N +G Y+C C + D
Sbjct: 1733 CTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPSYTGD 1782
Score = 35.5 bits (78), Expect = 0.81
Identities = 37/128 (28%), Positives = 49/128 (38%), Gaps = 31/128 (24%)
Query: 188 VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGR 247
+CR V C P C+NG P A C C +G+ + + + C GG R
Sbjct: 3470 ICRAV--CRFP---CQNGGICQRPNA--CSCPEGWMGRLCEEPICILPCLNGG------R 3516
Query: 248 CRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAG 307
C V ++C+C PG+T G C C PC G C N C C +
Sbjct: 3517 C---VAPYQCDCPPGWT----GSRCHTA-VCQS---PCLNGG--KCVRPN---RCHCLSS 3560
Query: 308 WKLVGRRC 315
W G C
Sbjct: 3561 W--TGHNC 3566
Score = 34.7 bits (76), Expect = 1.4
Identities = 34/106 (32%), Positives = 40/106 (37%), Gaps = 24/106 (22%)
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCE 343
PC G C N CSC GW +GR C + C LP + GG C Y C+
Sbjct: 3478 PCQNGG--ICQRPNA---CSCPEGW--MGRLC-EEPICI-LPCL-NGGRCV---APYQCD 3524
Query: 344 CPAGWRFDK--TAAV---------CVDERKELCYDEWEAGRCHRAR 378
CP GW + TA CV + C W C R R
Sbjct: 3525 CPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNCSRKR 3570
Score = 33.1 bits (72), Expect = 4.3
Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 3/53 (5%)
Query: 755 PGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNT-DGSYDCLC 806
PG +P CVC GYR +G+ C V A++PP NT + ++ C
Sbjct: 352 PGSTSPED--CVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAAC 402
Score = 32.3 bits (70), Expect = 7.5
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 14/88 (15%)
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPG 498
GG C + C CP+G++ G C + C L C NG Y+C C PG
Sbjct: 3482 GGICQRPNA---CSCPEGWM----GRLC-EEPICILP---CLNG--GRCVAPYQCDCPPG 3528
Query: 499 FTQGPDQTCVDVDECAE-GRASCTFRCH 525
+T T V C G+ RCH
Sbjct: 3529 WTGSRCHTAVCQSPCLNGGKCVRPNRCH 3556
>S54426-1|AAB25244.1| 109|Homo sapiens fibrillin protein.
Length = 109
Score = 120 bits (290), Expect = 2e-26
Identities = 55/109 (50%), Positives = 68/109 (62%), Gaps = 8/109 (7%)
Query: 391 EGAAWGRYCERCPAPDSAEFMRICQGG----MGRPNLTQDLDECRVRPDVCVGGRCVNTD 446
+G WG CE CP F +IC G +G + D+DEC+ PDVC G+C+NTD
Sbjct: 3 KGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECK-EPDVCKHGQCINTD 61
Query: 447 GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQC 495
GS+RCECP GY+LA G CVD DEC++ CGNGTC N GG+EC C
Sbjct: 62 GSYRCECPFGYILA--GNECVDTDECSVG-NPCGNGTCKNVIGGFECTC 107
Score = 94.3 bits (224), Expect = 2e-18
Identities = 49/108 (45%), Positives = 59/108 (54%), Gaps = 7/108 (6%)
Query: 115 WGRPPCRGMAQCVNLPG-AFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIG 172
WG PC C P AF CP G + D+ D+DEC + +C HG C NT G
Sbjct: 7 WG-DPCE---LCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDG 62
Query: 173 SYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDD 220
SYRCEC GY L N C D DECS P C NGTC+N+ G + C C++
Sbjct: 63 SYRCECPFGYILAGNECVDTDECSVGNP-CGNGTCKNVIGGFECTCEE 109
Score = 87.8 bits (208), Expect = 1e-16
Identities = 41/90 (45%), Positives = 56/90 (62%), Gaps = 7/90 (7%)
Query: 215 LCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRD 274
+C G GP++ VD++EC+E VC++G+C NT GS+RCEC GY L G C D
Sbjct: 25 ICPYGSGIIVGPDDSAVDMDECKEPD-VCKHGQCINTDGSYRCECPFGYILA--GNECVD 81
Query: 275 VDECDELPHPCGRDGNPSCTNTNGGYECSC 304
DEC + +PC GN +C N GG+EC+C
Sbjct: 82 TDEC-SVGNPC---GNGTCKNVIGGFECTC 107
Score = 80.6 bits (190), Expect = 2e-14
Identities = 39/92 (42%), Positives = 50/92 (54%), Gaps = 5/92 (5%)
Query: 446 DGSFRCECP--DGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP 503
D +FR CP G ++ PD S VD DEC +P +C +G C NT G Y C+C G+
Sbjct: 19 DEAFRQICPYGSGIIVGPDD-SAVDMDECK-EPDVCKHGQCINTDGSYRCECPFGYILAG 76
Query: 504 DQTCVDVDECAEGRASCTFRCHNTAGSFRCTC 535
++ CVD DEC+ G C N G F CTC
Sbjct: 77 NE-CVDTDECSVGNPCGNGTCKNVIGGFECTC 107
Score = 79.8 bits (188), Expect = 4e-14
Identities = 42/110 (38%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 28 GHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTP 87
G WG PCE CP A +C G + P + +DEC P +CK G C +T
Sbjct: 4 GEGWGDPCELCPTEPDEAFRQICPYGSGIIVGP-DDSAVDMDECK-EPDVCKHGQCINTD 61
Query: 88 TGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRC 137
++C C GY + C D DECS G PC G C N+ G FEC C
Sbjct: 62 GSYRCECPFGY--ILAGNECVDTDECSVGN-PC-GNGTCKNVIGGFECTC 107
Score = 77.0 bits (181), Expect = 3e-13
Identities = 36/86 (41%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Query: 493 CQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDID 552
C G GPD + VD+DEC E +C NT GS+RC CP+GY +A G C D D
Sbjct: 26 CPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDTD 83
Query: 553 ECVQEPRVCPHACENVVGSYICKCPE 578
EC C+NV+G + C C E
Sbjct: 84 ECSVGNPCGNGTCKNVIGGFECTCEE 109
Score = 73.3 bits (172), Expect = 3e-12
Identities = 31/69 (44%), Positives = 40/69 (57%), Gaps = 3/69 (4%)
Query: 191 DVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRN 250
D+DEC P VC++G C N G+Y C C G+ N+CVD +EC G C NG C+N
Sbjct: 42 DMDECKEP-DVCKHGQCINTDGSYRCECPFGYILA-GNECVDTDECSVGN-PCGNGTCKN 98
Query: 251 TVGSFRCEC 259
+G F C C
Sbjct: 99 VIGGFECTC 107
Score = 67.3 bits (157), Expect = 2e-10
Identities = 32/71 (45%), Positives = 39/71 (54%), Gaps = 5/71 (7%)
Query: 274 DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRCVDRDECKELPYVCAGGEC 333
D+DEC E P C + G C NT+G Y C C G+ L G CVD DEC + C G C
Sbjct: 42 DMDECKE-PDVC-KHGQ--CINTDGSYRCECPFGYILAGNECVDTDEC-SVGNPCGNGTC 96
Query: 334 RNFNGGYVCEC 344
+N GG+ C C
Sbjct: 97 KNVIGGFECTC 107
Score = 66.5 bits (155), Expect = 4e-10
Identities = 38/96 (39%), Positives = 45/96 (46%), Gaps = 10/96 (10%)
Query: 530 SFRCTCPYGYAV-AADGVHCRDIDECVQEPRVCPHA-CENVVGSYICKCPEGYRRTSAPQ 587
+FR CPYG + D+DEC +EP VC H C N GSY C+CP GY
Sbjct: 21 AFRQICPYGSGIIVGPDDSAVDMDEC-KEPDVCKHGQCINTDGSYRCECPFGYILAG--- 76
Query: 588 DSENACEDINECEEQEDLCSGGVCINTDGSFLCDCD 623
N C D +EC C G C N G F C C+
Sbjct: 77 ---NECVDTDECSVGNP-CGNGTCKNVIGGFECTCE 108
Score = 59.7 bits (138), Expect = 4e-08
Identities = 37/91 (40%), Positives = 43/91 (47%), Gaps = 7/91 (7%)
Query: 763 FRCVC--GPGYRPAGEVCA-DVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGAN 818
FR +C G G + A D+DEC P C C NTDGSY C C GY L G
Sbjct: 22 FRQICPYGSGIIVGPDDSAVDMDECK-EPDVCKHGQCINTDGSYRCECPFGYILA--GNE 78
Query: 819 CRDVDECERDTHTCQQICSNTEGSYECSCED 849
C D DEC C N G +EC+CE+
Sbjct: 79 CVDTDECSVGNPCGNGTCKNVIGGFECTCEE 109
Score = 55.2 bits (127), Expect = 9e-07
Identities = 33/117 (28%), Positives = 42/117 (35%), Gaps = 13/117 (11%)
Query: 690 GAAWGSECELCPAPGSPARLDLCTAVNLTPXXXXXXXXXXXXXXXXXXXXXXLDVFADVD 749
G WG CELCP A +C +D + D
Sbjct: 4 GEGWGDPCELCPTEPDEAFRQICP-------------YGSGIIVGPDDSAVDMDECKEPD 50
Query: 750 ECAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLC 806
C + G +RC C GY AG C D DEC+V P + C N G ++C C
Sbjct: 51 VCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTC 107
Score = 52.4 bits (120), Expect = 7e-06
Identities = 28/78 (35%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 576 CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
CP G P DS D++EC+E D+C G CINTDGS+ C+C G+ + G +C
Sbjct: 26 CPYGSGIIVGPDDS---AVDMDECKEP-DVCKHGQCINTDGSYRCECPFGYILA--GNEC 79
Query: 636 IDRRTGTCYRSLVSGRCE 653
+D + +G C+
Sbjct: 80 VDTDECSVGNPCGNGTCK 97
Score = 49.2 bits (112), Expect = 6e-05
Identities = 28/61 (45%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
Query: 302 CSCGAGWKLVGR--RCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD 359
C G+G +VG VD DECKE P VC G+C N +G Y CECP G+ V D
Sbjct: 26 CPYGSGI-IVGPDDSAVDMDECKE-PDVCKHGQCINTDGSYRCECPFGYILAGNECVDTD 83
Query: 360 E 360
E
Sbjct: 84 E 84
Score = 41.9 bits (94), Expect = 0.009
Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 5/73 (6%)
Query: 790 PCDQLCHNTDGSYDCLCRTGYEL---DEDGANCRDVDECERDTHTCQQICSNTEGSYECS 846
PC+ D ++ +C G + +D A D+DEC+ C NT+GSY C
Sbjct: 10 PCELCPTEPDEAFRQICPYGSGIIVGPDDSAV--DMDECKEPDVCKHGQCINTDGSYRCE 67
Query: 847 CEDGYEKRGDACV 859
C GY G+ CV
Sbjct: 68 CPFGYILAGNECV 80
>BC053933-1|AAH53933.1| 239|Homo sapiens EMR2 protein protein.
Length = 239
Score = 120 bits (290), Expect = 2e-26
Identities = 76/205 (37%), Positives = 99/205 (48%), Gaps = 27/205 (13%)
Query: 120 CRGMAQCVNLPGAFECRCPPGYR-----LTPSLDECEDVDECGDQRICDHG---DCRNTI 171
C + CVN A CRC PG+ +T ++ C+D++EC G DC NT
Sbjct: 33 CPQDSSCVN---ATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTE 89
Query: 172 GSYRCECKPGY-------TLR---ENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDD 220
GSY C C PGY T + EN C+DVDEC + +C++ GTC N G+Y C C
Sbjct: 90 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 149
Query: 221 GFKAGPNND--CVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRDVDE 277
GFK P + C DVNEC G C + C N VGS++C C PG+ N +
Sbjct: 150 GFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTV 209
Query: 278 CD--ELPHPCGRDGNPSCTNTNGGY 300
C+ EL RD S NG +
Sbjct: 210 CEGQELRSHVPRDPQTSDHMFNGAH 234
Score = 103 bits (248), Expect = 2e-21
Identities = 57/156 (36%), Positives = 82/156 (52%), Gaps = 23/156 (14%)
Query: 493 CQCSPGFTQ------GPDQTCVDVDECAE-GRASC-TFR-CHNTAGSFRCTCPYGYAVAA 543
C+C+PGF+ P +TC D++ECA + SC F C NT GS+ C C GY +
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 544 DGVH--------CRDIDECVQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENAC 593
C+D+DEC Q PR+C C N +GSY C+C G++ P+D + C
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK--FIPEDPK-VC 161
Query: 594 EDINECEEQEDLCSGGV-CINTDGSFLCDCDAGFEP 628
D+NEC ++ C C+N GS+ C C G++P
Sbjct: 162 TDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQP 197
Score = 99 bits (238), Expect = 3e-20
Identities = 59/184 (32%), Positives = 86/184 (46%), Gaps = 24/184 (13%)
Query: 146 SLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY-------TLRENVCRDVDECSRP 198
+L E D G R C + + + C C PG+ T C D++EC+
Sbjct: 17 TLPGAETQDSRGCARWCPQDS--SCVNATACRCNPGFSSFSEIITTPMETCDDINECATL 74
Query: 199 RPV-C-RNGTCENLPGAYLCHCDDG---------FKAGPNNDCVDVNECREGGMVCRN-G 246
V C + C N G+Y C C G FK N C DV+EC++ +C++ G
Sbjct: 75 SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYG 134
Query: 247 RCRNTVGSFRCECAPGYT-LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C NT+GS+ C+C PG+ + D + C DV+EC +PC + C N G Y+C C
Sbjct: 135 TCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPC--HSSTHCLNNVGSYQCRCR 192
Query: 306 AGWK 309
GW+
Sbjct: 193 PGWQ 196
Score = 96.3 bits (229), Expect = 4e-19
Identities = 54/152 (35%), Positives = 77/152 (50%), Gaps = 21/152 (13%)
Query: 107 CRDVDECSW-GRPPCRGMAQCVNLPGAFECRCPPGYR--------LTPSLDECEDVDECG 157
C D++EC+ + C + C N G+++C C PGY S + C+DVDEC
Sbjct: 65 CDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQ 124
Query: 158 DQ-RIC-DHGDCRNTIGSYRCECKPGYTL---RENVCRDVDECSRPRPVCRNGT-CENLP 211
R+C +G C NT+GSY C+C PG+ VC DV+EC+ + C + T C N
Sbjct: 125 QNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNV 184
Query: 212 GAYLCHCDDGFKA------GPNNDCVDVNECR 237
G+Y C C G++ GPNN + E R
Sbjct: 185 GSYQCRCRPGWQPIPGSPNGPNNTVCEGQELR 216
Score = 94.3 bits (224), Expect = 2e-18
Identities = 50/129 (38%), Positives = 66/129 (51%), Gaps = 15/129 (11%)
Query: 426 DLDECRVRPDVCVG--GRCVNTDGSFRCECPDGYVLAPDGLS--------CVDADECALD 475
D++EC V G C NT+GS+ C C GY + C D DEC +
Sbjct: 67 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 126
Query: 476 PRICGN-GTCSNTRGGYECQCSPGFTQGPD--QTCVDVDECAEGRASC--TFRCHNTAGS 530
PR+C + GTC NT G Y CQC PGF P+ + C DV+EC G+ C + C N GS
Sbjct: 127 PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGS 186
Query: 531 FRCTCPYGY 539
++C C G+
Sbjct: 187 YQCRCRPGW 195
Score = 91.1 bits (216), Expect = 2e-17
Identities = 62/180 (34%), Positives = 83/180 (46%), Gaps = 27/180 (15%)
Query: 190 RDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA------GPNNDCVDVNECREGGMV- 242
+D C+R P ++ +C N A C C+ GF + P C D+NEC V
Sbjct: 24 QDSRGCARWCP--QDSSCVN---ATACRCNPGFSSFSEIITTPMETCDDINECATLSKVS 78
Query: 243 C-RNGRCRNTVGSFRCECAPGY-------TLTADGRN-CRDVDECDELPHPCGRDGNPSC 293
C + C NT GS+ C C+PGY T + N C+DVDEC + P C G +C
Sbjct: 79 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYG--TC 136
Query: 294 TNTNGGYECSCGAGWKLVG---RRCVDRDECKELPYVC-AGGECRNFNGGYVCECPAGWR 349
NT G Y C C G+K + + C D +EC C + C N G Y C C GW+
Sbjct: 137 VNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 196
Score = 81.8 bits (193), Expect = 9e-15
Identities = 48/166 (28%), Positives = 76/166 (45%), Gaps = 11/166 (6%)
Query: 1 MEWNEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
ME ++ CA V K+ C + ++ C SP + + G K + N
Sbjct: 62 METCDDINECATLSKVSCGKFSDCWNTEGSYDCVC-------SPGYEPVSGAKT--FKNE 112
Query: 61 VTNETKPIDECDIMPQLCKP-GTCHDTPTGFQCGCDHGYEH-DNTSHLCRDVDECSWGRP 118
N + +DEC P+LCK GTC +T + C C G++ +C DV+EC+ G+
Sbjct: 113 SENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQN 172
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDH 164
PC C+N G+++CRC PG++ P + C Q + H
Sbjct: 173 PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEGQELRSH 218
Score = 77.8 bits (183), Expect = 2e-13
Identities = 41/107 (38%), Positives = 50/107 (46%), Gaps = 15/107 (14%)
Query: 761 GRFRCVCGPGYRPAG----------EVCADVDECAVRPPPCDQL--CHNTDGSYDCLCRT 808
G + CVC PGY P C DVDEC P C C NT GSY C C
Sbjct: 90 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 149
Query: 809 GYE-LDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE 852
G++ + ED C DV+EC + C C N GSY+C C G++
Sbjct: 150 GFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 196
Score = 74.5 bits (175), Expect = 1e-12
Identities = 35/85 (41%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
Query: 422 NLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAP-DGLSCVDADECALDPRIC 479
N QD+DEC+ P +C G CVNT GS+ C+C G+ P D C D +EC C
Sbjct: 115 NTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPC 174
Query: 480 GNGT-CSNTRGGYECQCSPGFTQGP 503
+ T C N G Y+C+C PG+ P
Sbjct: 175 HSSTHCLNNVGSYQCRCRPGWQPIP 199
Score = 74.1 bits (174), Expect = 2e-12
Identities = 40/108 (37%), Positives = 56/108 (51%), Gaps = 20/108 (18%)
Query: 765 CVCGPGYRPAGEV-------CADVDECA-VRPPPCDQL--CHNTDGSYDCLCRTGYE--- 811
C C PG+ E+ C D++ECA + C + C NT+GSYDC+C GYE
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 812 -----LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE 852
+E C+DVDEC+++ C+ C NT GSY C C G++
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 152
Score = 73.3 bits (172), Expect = 3e-12
Identities = 41/99 (41%), Positives = 53/99 (53%), Gaps = 9/99 (9%)
Query: 548 CRDIDECVQEPRV-CPHA--CENVVGSYICKCPEGYRRTSAPQ----DSENACEDINECE 600
C DI+EC +V C C N GSY C C GY S + +SEN C+D++EC+
Sbjct: 65 CDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQ 124
Query: 601 EQEDLC-SGGVCINTDGSFLCDCDAGFE-PSEDGTDCID 637
+ LC S G C+NT GS+ C C GF+ ED C D
Sbjct: 125 QNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTD 163
Score = 68.9 bits (161), Expect = 7e-11
Identities = 41/126 (32%), Positives = 59/126 (46%), Gaps = 20/126 (15%)
Query: 252 VGSFRCECAPGYT-----LTADGRNCRDVDECDELPH-PCGRDGNPSCTNTNGGYECSCG 305
V + C C PG++ +T C D++EC L CG+ + C NT G Y+C C
Sbjct: 40 VNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSD--CWNTEGSYDCVCS 97
Query: 306 AGWKLVG----------RRCVDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRF-DKT 353
G++ V C D DEC++ P +C G C N G Y C+C G++F +
Sbjct: 98 PGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPED 157
Query: 354 AAVCVD 359
VC D
Sbjct: 158 PKVCTD 163
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/93 (36%), Positives = 41/93 (44%), Gaps = 13/93 (13%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYRPAGE---VCADVDECAVRPPPCDQLC 795
DVDEC P LC G + C C PG++ E VC DV+EC PC
Sbjct: 119 DVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSST 178
Query: 796 H--NTDGSYDCLCRTGYELDEDGANCRDVDECE 826
H N GSY C CR G++ N + CE
Sbjct: 179 HCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCE 211
Score = 47.2 bits (107), Expect = 2e-04
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 6/94 (6%)
Query: 556 QEPRVCPHAC---ENVVGSYICKCPEGYRRTSAPQDSE-NACEDINECEEQEDLCSGGV- 610
Q+ R C C + V + C+C G+ S + C+DINEC + G
Sbjct: 24 QDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFS 83
Query: 611 -CINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
C NT+GS+ C C G+EP + TC
Sbjct: 84 DCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTC 117
Score = 44.0 bits (99), Expect = 0.002
Identities = 55/211 (26%), Positives = 74/211 (35%), Gaps = 41/211 (19%)
Query: 265 LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR-------RCVD 317
LT G +D C C +D SC N C C G+ C D
Sbjct: 16 LTLPGAETQDSRGCARW---CPQDS--SCVNATA---CRCNPGFSSFSEIITTPMETCDD 67
Query: 318 RDECKELPYVCAG--GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCH 375
+EC L V G +C N G Y C C G+ A +E + C D C
Sbjct: 68 INECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQD---VDECQ 124
Query: 376 RARPLQLARPECCCSEGA---AWGRY-CERCPAPDSAEFMRICQGGMGRPNLTQDLDECR 431
+ P C S G G Y C+ P F I + P + D++EC
Sbjct: 125 Q-------NPRLCKSYGTCVNTLGSYTCQCLPG-----FKFIPED----PKVCTDVNECT 168
Query: 432 VRPDVCVGG-RCVNTDGSFRCECPDGYVLAP 461
+ C C+N GS++C C G+ P
Sbjct: 169 SGQNPCHSSTHCLNNVGSYQCRCRPGWQPIP 199
>BC047916-1|AAH47916.1| 347|Homo sapiens SCUBE1 protein protein.
Length = 347
Score = 120 bits (290), Expect = 2e-26
Identities = 90/294 (30%), Positives = 120/294 (40%), Gaps = 34/294 (11%)
Query: 191 DVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECRE----GGMVCRN 245
DVDECS C + C+N P +Y C C G+K G C D++EC GG V
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK-GEGKQCEDIDECENDYYNGGCV--- 88
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C N G++RC C G+ L DG NC DVDEC + C C N G YEC C
Sbjct: 89 HECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGC----QQICVNAMGSYECQCH 144
Query: 306 AGWKLVGRR--CVDRD----ECKELPYVCAGGECRNF-NGGYVCECPAGWRFDKTAAVCV 358
+G+ L + C+ R C + CA CR GG C+C G+ + C
Sbjct: 145 SGFFLSDNQHTCIHRSNEGMNCMNKDHGCA-HICRETPKGGVACDCRPGFDLAQNQKDCT 203
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
C + G C + P C C + A C D A R
Sbjct: 204 ----LTC--NYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIEKDEAAIERSQFNAT 257
Query: 419 GRPNLTQDLDECRVRPDVCV---GG---RCVNTDGSFRCECPDGYVLAPDGLSC 466
++ + + R+ + C GG C +T RC CP G+ L PDG +C
Sbjct: 258 SVADVDKRVKR-RLLMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTC 310
Score = 120 bits (288), Expect = 3e-26
Identities = 94/298 (31%), Positives = 126/298 (42%), Gaps = 53/298 (17%)
Query: 109 DVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRI---CDHG 165
DVDECS G C A C N P +++C C PGY+ +CED+DEC + C H
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDECENDYYNGGCVH- 89
Query: 166 DCRNTIGSYRCECKPGYTLRE--NVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFK 223
+C N G+YRC C G+ L + C DVDEC C+ C N G+Y C C GF
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSGFF 148
Query: 224 AGPNNDCVDVNECREGGMVCRNGR------CRNT-VGSFRCECAPGYTLTADGRNCRDVD 276
N ++ E GM C N CR T G C+C PG+ L + ++C
Sbjct: 149 LSDNQHTC-IHRSNE-GMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDC--TL 204
Query: 277 ECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL--VGRRCVDRDEC------------- 321
C+ C SC +T+ G C C + L GR C+++DE
Sbjct: 205 TCNYGNGGC----QHSCEDTDTGPTCGCHQKYALHSDGRTCIEKDEAAIERSQFNATSVA 260
Query: 322 --------KELPYVCA---GG---ECRNFNGGYVCECPAGWRFDKTAAVCVDERKELC 365
+ L CA GG C++ G C CP G+ C + ELC
Sbjct: 261 DVDKRVKRRLLMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKGQHVELC 318
Score = 118 bits (285), Expect = 7e-26
Identities = 58/173 (33%), Positives = 85/173 (49%), Gaps = 6/173 (3%)
Query: 467 VDADECALDPRICG-NGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEG--RASCTFR 523
VD DEC+ C + C NT Y+C C PG+ +G + C D+DEC C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGY-KGEGKQCEDIDECENDYYNGGCVHE 90
Query: 524 CHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRT 583
C N G++RCTC G+ +A DG +C D+DEC C C N +GSY C+C G+ +
Sbjct: 91 CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLS 150
Query: 584 SAPQDSENACEDINECEEQEDLCSGGVCINT-DGSFLCDCDAGFEPSEDGTDC 635
+ + C ++ C+ +C T G CDC GF+ +++ DC
Sbjct: 151 DNQHTCIHRSNEGMNCMNKDHGCA-HICRETPKGGVACDCRPGFDLAQNQKDC 202
Score = 114 bits (275), Expect = 1e-24
Identities = 94/324 (29%), Positives = 134/324 (41%), Gaps = 49/324 (15%)
Query: 231 VDVNECREGGMVCR-NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDG 289
VDV+EC EG C + C+NT S++C C PGY +G+ C D+DEC+ + G
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDECENDYYNGGCVH 89
Query: 290 NPSCTNTNGGYECSCGAGWKLV--GRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
C N G Y C+C G+ L G C+D DEC++ C C N G Y C+C +G
Sbjct: 90 E--CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSG 146
Query: 348 WRFDKTAAVCVDERKE--LCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
+ C+ E C ++ + G H C E G C+ P
Sbjct: 147 FFLSDNQHTCIHRSNEGMNCMNK-DHGCAH------------ICRETPKGGVACDCRPGF 193
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLS 465
D A+ + C LT C C C +TD C C Y L DG +
Sbjct: 194 DLAQNQKDC-------TLT-----CNYGNGGCQHS-CEDTDTGPTCGCHQKYALHSDGRT 240
Query: 466 CVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCH 525
C++ DE A++ R N T S + + ++ CA C C
Sbjct: 241 CIEKDEAAIE-RSQFNAT------------SVADVDKRVKRRLLMETCAVNNGGCDRTCK 287
Query: 526 NTAGSFRCTCPYGYAVAADGVHCR 549
+TA RC+CP G+ + DG C+
Sbjct: 288 DTATGVRCSCPVGFTLQPDGKTCK 311
Score = 111 bits (266), Expect = 1e-23
Identities = 74/240 (30%), Positives = 97/240 (40%), Gaps = 20/240 (8%)
Query: 416 GGMGRPNLTQDLDECRVRPDVC-VGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECAL 474
GG G P + D+DEC D C + C NT S++C C GY +G C D DEC
Sbjct: 24 GGSGLPG-SVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGY--KGEGKQCEDIDECEN 80
Query: 475 DPRICGN-GTCSNTRGGYECQCSPGFTQGPD-QTCVDVDECAEGRASCTFRCHNTAGSFR 532
D G C N G Y C C GF D C+DVDEC + C C N GS+
Sbjct: 81 DYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYE 140
Query: 533 CTCPYGYAVAADGVHC----RDIDECVQEPRVCPHAC-ENVVGSYICKCPEGYRRTSAPQ 587
C C G+ ++ + C + C+ + C H C E G C C G+ +
Sbjct: 141 CQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQK 200
Query: 588 DSENACEDINE-CEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRS 646
D C N C+ C +TD C C + DG CI++ RS
Sbjct: 201 DCTLTCNYGNGGCQHS--------CEDTDTGPTCGCHQKYALHSDGRTCIEKDEAAIERS 252
Score = 106 bits (254), Expect = 4e-22
Identities = 50/115 (43%), Positives = 63/115 (54%), Gaps = 10/115 (8%)
Query: 747 DVDECAA------IPGLC--APGRFRCVCGPGYRPAGEVCADVDECA--VRPPPCDQLCH 796
DVDEC+ I +C P ++C+C PGY+ G+ C D+DEC C C
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHECI 92
Query: 797 NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
N G+Y C C G+ L DG NC DVDEC+ + CQQIC N GSYEC C G+
Sbjct: 93 NIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGF 147
Score = 95.1 bits (226), Expect = 9e-19
Identities = 76/264 (28%), Positives = 109/264 (41%), Gaps = 38/264 (14%)
Query: 413 ICQGGM-GRPNLTQDLDECRVRPDVCVGG---RCVNTDGSFRCECPDGYVLAPDGLSCVD 468
+C+ G G +D+DEC D GG C+N G++RC C DG++LA DG +C+D
Sbjct: 60 LCKPGYKGEGKQCEDIDECE--NDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLD 117
Query: 469 ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQ-TCV----DVDECAEGRASCTFR 523
DEC + C C N G YECQC GF +Q TC+ + C C
Sbjct: 118 VDECQDNNGGC-QQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHI 176
Query: 524 CHNT-AGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR- 581
C T G C C G+ +A + C C C H+CE+ C C + Y
Sbjct: 177 CRETPKGGVACDCRPGFDLAQNQKDC--TLTCNYGNGGCQHSCEDTDTGPTCGCHQKYAL 234
Query: 582 ----RTSAPQD---------SENACEDINECEEQE---DLC---SGG---VCINTDGSFL 619
RT +D + + D+++ ++ + C +GG C +T
Sbjct: 235 HSDGRTCIEKDEAAIERSQFNATSVADVDKRVKRRLLMETCAVNNGGCDRTCKDTATGVR 294
Query: 620 CDCDAGFEPSEDGTDCIDRRTGTC 643
C C GF DG C + C
Sbjct: 295 CSCPVGFTLQPDGKTCKGQHVELC 318
Score = 75.8 bits (178), Expect = 6e-13
Identities = 36/100 (36%), Positives = 48/100 (48%), Gaps = 7/100 (7%)
Query: 760 PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 817
PG +RC C G+ A G C DVDEC C Q+C N GSY+C C +G+ L ++
Sbjct: 95 PGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQH 154
Query: 818 NC----RDVDECERDTHTCQQICSNT-EGSYECSCEDGYE 852
C + C H C IC T +G C C G++
Sbjct: 155 TCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFD 194
Score = 45.2 bits (102), Expect = 0.001
Identities = 33/123 (26%), Positives = 45/123 (36%), Gaps = 15/123 (12%)
Query: 747 DVDECAAIPGLC------APGRFRCVCGPGYRPAGE--VCADVDE----CAVRPPPCDQL 794
DVDEC G C A G + C C G+ + C C + C +
Sbjct: 117 DVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHI 176
Query: 795 CHNTD-GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C T G C CR G++L ++ +C C CQ C +T+ C C Y
Sbjct: 177 CRETPKGGVACDCRPGFDLAQNQKDCTLT--CNYGNGGCQHSCEDTDTGPTCGCHQKYAL 234
Query: 854 RGD 856
D
Sbjct: 235 HSD 237
Score = 44.8 bits (101), Expect = 0.001
Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Query: 821 DVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDAC 858
DVDEC T C IC NT SY+C C+ GY+ G C
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQC 72
Score = 38.3 bits (85), Expect = 0.11
Identities = 23/74 (31%), Positives = 26/74 (35%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
CA I G C C PG+ A C C C +TD C C Y
Sbjct: 173 CAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKY 232
Query: 811 ELDEDGANCRDVDE 824
L DG C + DE
Sbjct: 233 ALHSDGRTCIEKDE 246
Score = 37.1 bits (82), Expect = 0.27
Identities = 14/40 (35%), Positives = 20/40 (50%)
Query: 781 VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 820
++ CAV CD+ C +T C C G+ L DG C+
Sbjct: 272 METCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCK 311
>BC034949-1|AAH34949.1| 239|Homo sapiens EMR2 protein protein.
Length = 239
Score = 120 bits (290), Expect = 2e-26
Identities = 76/205 (37%), Positives = 99/205 (48%), Gaps = 27/205 (13%)
Query: 120 CRGMAQCVNLPGAFECRCPPGYR-----LTPSLDECEDVDECGDQRICDHG---DCRNTI 171
C + CVN A CRC PG+ +T ++ C+D++EC G DC NT
Sbjct: 33 CPQDSSCVN---ATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTE 89
Query: 172 GSYRCECKPGY-------TLR---ENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDD 220
GSY C C PGY T + EN C+DVDEC + +C++ GTC N G+Y C C
Sbjct: 90 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 149
Query: 221 GFKAGPNND--CVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCRDVDE 277
GFK P + C DVNEC G C + C N VGS++C C PG+ N +
Sbjct: 150 GFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTV 209
Query: 278 CD--ELPHPCGRDGNPSCTNTNGGY 300
C+ EL RD S NG +
Sbjct: 210 CEGQELRSHVPRDPQTSDHMFNGAH 234
Score = 103 bits (248), Expect = 2e-21
Identities = 57/156 (36%), Positives = 82/156 (52%), Gaps = 23/156 (14%)
Query: 493 CQCSPGFTQ------GPDQTCVDVDECAE-GRASC-TFR-CHNTAGSFRCTCPYGYAVAA 543
C+C+PGF+ P +TC D++ECA + SC F C NT GS+ C C GY +
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 544 DGVH--------CRDIDECVQEPRVCPH--ACENVVGSYICKCPEGYRRTSAPQDSENAC 593
C+D+DEC Q PR+C C N +GSY C+C G++ P+D + C
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK--FIPEDPK-VC 161
Query: 594 EDINECEEQEDLCSGGV-CINTDGSFLCDCDAGFEP 628
D+NEC ++ C C+N GS+ C C G++P
Sbjct: 162 TDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQP 197
Score = 99 bits (238), Expect = 3e-20
Identities = 59/184 (32%), Positives = 86/184 (46%), Gaps = 24/184 (13%)
Query: 146 SLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGY-------TLRENVCRDVDECSRP 198
+L E D G R C + + + C C PG+ T C D++EC+
Sbjct: 17 TLPGAETQDSRGCARWCPQDS--SCVNATACRCNPGFSSFSEIITTPMETCDDINECATL 74
Query: 199 RPV-C-RNGTCENLPGAYLCHCDDG---------FKAGPNNDCVDVNECREGGMVCRN-G 246
V C + C N G+Y C C G FK N C DV+EC++ +C++ G
Sbjct: 75 SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYG 134
Query: 247 RCRNTVGSFRCECAPGYT-LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCG 305
C NT+GS+ C+C PG+ + D + C DV+EC +PC + C N G Y+C C
Sbjct: 135 TCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPC--HSSTHCLNNVGSYQCRCR 192
Query: 306 AGWK 309
GW+
Sbjct: 193 PGWQ 196
Score = 96.3 bits (229), Expect = 4e-19
Identities = 54/152 (35%), Positives = 77/152 (50%), Gaps = 21/152 (13%)
Query: 107 CRDVDECSW-GRPPCRGMAQCVNLPGAFECRCPPGYR--------LTPSLDECEDVDECG 157
C D++EC+ + C + C N G+++C C PGY S + C+DVDEC
Sbjct: 65 CDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQ 124
Query: 158 DQ-RIC-DHGDCRNTIGSYRCECKPGYTL---RENVCRDVDECSRPRPVCRNGT-CENLP 211
R+C +G C NT+GSY C+C PG+ VC DV+EC+ + C + T C N
Sbjct: 125 QNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNV 184
Query: 212 GAYLCHCDDGFKA------GPNNDCVDVNECR 237
G+Y C C G++ GPNN + E R
Sbjct: 185 GSYQCRCRPGWQPIPGSPNGPNNTVCEGQELR 216
Score = 94.3 bits (224), Expect = 2e-18
Identities = 50/129 (38%), Positives = 66/129 (51%), Gaps = 15/129 (11%)
Query: 426 DLDECRVRPDVCVG--GRCVNTDGSFRCECPDGYVLAPDGLS--------CVDADECALD 475
D++EC V G C NT+GS+ C C GY + C D DEC +
Sbjct: 67 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 126
Query: 476 PRICGN-GTCSNTRGGYECQCSPGFTQGPD--QTCVDVDECAEGRASC--TFRCHNTAGS 530
PR+C + GTC NT G Y CQC PGF P+ + C DV+EC G+ C + C N GS
Sbjct: 127 PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGS 186
Query: 531 FRCTCPYGY 539
++C C G+
Sbjct: 187 YQCRCRPGW 195
Score = 91.1 bits (216), Expect = 2e-17
Identities = 62/180 (34%), Positives = 83/180 (46%), Gaps = 27/180 (15%)
Query: 190 RDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA------GPNNDCVDVNECREGGMV- 242
+D C+R P ++ +C N A C C+ GF + P C D+NEC V
Sbjct: 24 QDSRGCARWCP--QDSSCVN---ATACRCNPGFSSFSEIITTPMETCDDINECATLSKVS 78
Query: 243 C-RNGRCRNTVGSFRCECAPGY-------TLTADGRN-CRDVDECDELPHPCGRDGNPSC 293
C + C NT GS+ C C+PGY T + N C+DVDEC + P C G +C
Sbjct: 79 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYG--TC 136
Query: 294 TNTNGGYECSCGAGWKLVG---RRCVDRDECKELPYVC-AGGECRNFNGGYVCECPAGWR 349
NT G Y C C G+K + + C D +EC C + C N G Y C C GW+
Sbjct: 137 VNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 196
Score = 81.8 bits (193), Expect = 9e-15
Identities = 48/166 (28%), Positives = 76/166 (45%), Gaps = 11/166 (6%)
Query: 1 MEWNEEDQSCAGAVGVPQTKYLCCCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINP 60
ME ++ CA V K+ C + ++ C SP + + G K + N
Sbjct: 62 METCDDINECATLSKVSCGKFSDCWNTEGSYDCVC-------SPGYEPVSGAKT--FKNE 112
Query: 61 VTNETKPIDECDIMPQLCKP-GTCHDTPTGFQCGCDHGYEH-DNTSHLCRDVDECSWGRP 118
N + +DEC P+LCK GTC +T + C C G++ +C DV+EC+ G+
Sbjct: 113 SENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQN 172
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDH 164
PC C+N G+++CRC PG++ P + C Q + H
Sbjct: 173 PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEGQELRSH 218
Score = 77.8 bits (183), Expect = 2e-13
Identities = 41/107 (38%), Positives = 50/107 (46%), Gaps = 15/107 (14%)
Query: 761 GRFRCVCGPGYRPAG----------EVCADVDECAVRPPPCDQL--CHNTDGSYDCLCRT 808
G + CVC PGY P C DVDEC P C C NT GSY C C
Sbjct: 90 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 149
Query: 809 GYE-LDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE 852
G++ + ED C DV+EC + C C N GSY+C C G++
Sbjct: 150 GFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 196
Score = 74.5 bits (175), Expect = 1e-12
Identities = 35/85 (41%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
Query: 422 NLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAP-DGLSCVDADECALDPRIC 479
N QD+DEC+ P +C G CVNT GS+ C+C G+ P D C D +EC C
Sbjct: 115 NTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPC 174
Query: 480 GNGT-CSNTRGGYECQCSPGFTQGP 503
+ T C N G Y+C+C PG+ P
Sbjct: 175 HSSTHCLNNVGSYQCRCRPGWQPIP 199
Score = 74.1 bits (174), Expect = 2e-12
Identities = 40/108 (37%), Positives = 56/108 (51%), Gaps = 20/108 (18%)
Query: 765 CVCGPGYRPAGEV-------CADVDECA-VRPPPCDQL--CHNTDGSYDCLCRTGYE--- 811
C C PG+ E+ C D++ECA + C + C NT+GSYDC+C GYE
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 812 -----LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE 852
+E C+DVDEC+++ C+ C NT GSY C C G++
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 152
Score = 73.3 bits (172), Expect = 3e-12
Identities = 41/99 (41%), Positives = 53/99 (53%), Gaps = 9/99 (9%)
Query: 548 CRDIDECVQEPRV-CPHA--CENVVGSYICKCPEGYRRTSAPQ----DSENACEDINECE 600
C DI+EC +V C C N GSY C C GY S + +SEN C+D++EC+
Sbjct: 65 CDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQ 124
Query: 601 EQEDLC-SGGVCINTDGSFLCDCDAGFE-PSEDGTDCID 637
+ LC S G C+NT GS+ C C GF+ ED C D
Sbjct: 125 QNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTD 163
Score = 68.9 bits (161), Expect = 7e-11
Identities = 41/126 (32%), Positives = 59/126 (46%), Gaps = 20/126 (15%)
Query: 252 VGSFRCECAPGYT-----LTADGRNCRDVDECDELPH-PCGRDGNPSCTNTNGGYECSCG 305
V + C C PG++ +T C D++EC L CG+ + C NT G Y+C C
Sbjct: 40 VNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSD--CWNTEGSYDCVCS 97
Query: 306 AGWKLVG----------RRCVDRDECKELPYVCAG-GECRNFNGGYVCECPAGWRF-DKT 353
G++ V C D DEC++ P +C G C N G Y C+C G++F +
Sbjct: 98 PGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPED 157
Query: 354 AAVCVD 359
VC D
Sbjct: 158 PKVCTD 163
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/93 (36%), Positives = 41/93 (44%), Gaps = 13/93 (13%)
Query: 747 DVDECAAIPGLCAP--------GRFRCVCGPGYRPAGE---VCADVDECAVRPPPCDQLC 795
DVDEC P LC G + C C PG++ E VC DV+EC PC
Sbjct: 119 DVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSST 178
Query: 796 H--NTDGSYDCLCRTGYELDEDGANCRDVDECE 826
H N GSY C CR G++ N + CE
Sbjct: 179 HCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCE 211
Score = 47.2 bits (107), Expect = 2e-04
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 6/94 (6%)
Query: 556 QEPRVCPHAC---ENVVGSYICKCPEGYRRTSAPQDSE-NACEDINECEEQEDLCSGGV- 610
Q+ R C C + V + C+C G+ S + C+DINEC + G
Sbjct: 24 QDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFS 83
Query: 611 -CINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
C NT+GS+ C C G+EP + TC
Sbjct: 84 DCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTC 117
Score = 44.0 bits (99), Expect = 0.002
Identities = 55/211 (26%), Positives = 74/211 (35%), Gaps = 41/211 (19%)
Query: 265 LTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGR-------RCVD 317
LT G +D C C +D SC N C C G+ C D
Sbjct: 16 LTLPGAETQDSRGCARW---CPQDS--SCVNATA---CRCNPGFSSFSEIITTPMETCDD 67
Query: 318 RDECKELPYVCAG--GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCH 375
+EC L V G +C N G Y C C G+ A +E + C D C
Sbjct: 68 INECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQD---VDECQ 124
Query: 376 RARPLQLARPECCCSEGA---AWGRY-CERCPAPDSAEFMRICQGGMGRPNLTQDLDECR 431
+ P C S G G Y C+ P F I + P + D++EC
Sbjct: 125 Q-------NPRLCKSYGTCVNTLGSYTCQCLPG-----FKFIPED----PKVCTDVNECT 168
Query: 432 VRPDVCVGG-RCVNTDGSFRCECPDGYVLAP 461
+ C C+N GS++C C G+ P
Sbjct: 169 SGQNPCHSSTHCLNNVGSYQCRCRPGWQPIP 199
>L13720-1|AAA58494.1| 678|Homo sapiens growth-arrest-specific
protein protein.
Length = 678
Score = 120 bits (288), Expect = 3e-26
Identities = 70/177 (39%), Positives = 88/177 (49%), Gaps = 20/177 (11%)
Query: 69 DECDIMPQLC-KPGT--CHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMA 124
D+C P C + GT C D F C C G+ LC +DV+ECS C +
Sbjct: 118 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGWG----GRLCDKDVNECSQENGGC--LQ 169
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPG--Y 182
C N PG+F C C G+ L+ C+D+DEC D C C+N GSY C C G Y
Sbjct: 170 ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAY 229
Query: 183 TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCD--DGFKAGPNND-CVDVNEC 236
+ +E CRDVDEC + R C C N PG+Y CHCD G K + D C D+ C
Sbjct: 230 SSQEKACRDVDECLQGR--CEQ-VCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 283
Score = 118 bits (285), Expect = 7e-26
Identities = 63/173 (36%), Positives = 89/173 (51%), Gaps = 16/173 (9%)
Query: 470 DECALDPRIC---GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHN 526
D+C +P C G C + G + C C G+ G DV+EC++ C CHN
Sbjct: 118 DQCTPNP--CDRKGTQACQDLMGNFFCLCKAGW--GGRLCDKDVNECSQENGGCLQICHN 173
Query: 527 TAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAP 586
GSF C+C G+ +++DG C+DIDEC C+N+ GSY C C EG+ +S
Sbjct: 174 KPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSS-- 231
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCD--AGFEPSEDGTDCID 637
E AC D++EC + C VC+N+ GS+ C CD G + S+D C D
Sbjct: 232 --QEKACRDVDEC--LQGRCE-QVCVNSPGSYTCHCDGRGGLKLSQDMDTCED 279
Score = 110 bits (265), Expect = 2e-23
Identities = 58/149 (38%), Positives = 74/149 (49%), Gaps = 7/149 (4%)
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
F +C+ G G +D++EC C+ C N GSF C C G+ L+ DG +C D
Sbjct: 140 FFCLCKAGWGGRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDI 198
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTFRCHNTA 528
DECA D CG C N G Y C C GF ++ C DVDEC +GR C C N+
Sbjct: 199 DECA-DSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGR--CEQVCVNSP 255
Query: 529 GSFRCTCP--YGYAVAADGVHCRDIDECV 555
GS+ C C G ++ D C DI CV
Sbjct: 256 GSYTCHCDGRGGLKLSQDMDTCEDILPCV 284
Score = 98.3 bits (234), Expect = 1e-19
Identities = 69/200 (34%), Positives = 89/200 (44%), Gaps = 20/200 (10%)
Query: 166 DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGT--CENLPGAYLCHCDDGFK 223
DC N GS + T +N+ D+C+ P P R GT C++L G + C C G+
Sbjct: 94 DCINKYGSPYTKNSGFATCVQNL---PDQCT-PNPCDRKGTQACQDLMGNFFCLCKAGW- 148
Query: 224 AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPH 283
G DVNEC + C C N GSF C C G+ L++DGR C+D+DEC +
Sbjct: 149 -GGRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECAD-SE 205
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYV 341
C G C N G Y C C G+ + C D DEC L C C N G Y
Sbjct: 206 AC---GEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC--LQGRCE-QVCVNSPGSYT 259
Query: 342 CECP--AGWRFDKTAAVCVD 359
C C G + + C D
Sbjct: 260 CHCDGRGGLKLSQDMDTCED 279
Score = 94.7 bits (225), Expect = 1e-18
Identities = 43/102 (42%), Positives = 59/102 (57%), Gaps = 7/102 (6%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G F C+C G+ G +C DV+EC+ C Q+CHN GS+ C C +G+EL DG C
Sbjct: 138 GNFFCLCKAGW--GGRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTC 195
Query: 820 RDVDECERDTHTCQQI-CSNTEGSYECSCEDG--YEKRGDAC 858
+D+DEC D+ C + C N GSY C C++G Y + AC
Sbjct: 196 QDIDEC-ADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKAC 236
Score = 89.4 bits (212), Expect = 5e-17
Identities = 44/110 (40%), Positives = 56/110 (50%), Gaps = 10/110 (9%)
Query: 747 DVDECAAIPGLCA------PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNT 798
DV+EC+ G C PG F C C G+ + G C D+DECA + C N
Sbjct: 156 DVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNL 215
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCE 848
GSY CLC G+ CRDVDEC + C+Q+C N+ GSY C C+
Sbjct: 216 PGSYSCLCDEGFAYSSQEKACRDVDECLQG--RCEQVCVNSPGSYTCHCD 263
Score = 64.9 bits (151), Expect = 1e-09
Identities = 32/80 (40%), Positives = 44/80 (55%), Gaps = 11/80 (13%)
Query: 782 DECAVRPPPCD----QLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQIC 836
D+C P PCD Q C + G++ CLC+ G+ G C +DV+EC ++ C QIC
Sbjct: 118 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGW----GGRLCDKDVNECSQENGGCLQIC 171
Query: 837 SNTEGSYECSCEDGYEKRGD 856
N GS+ CSC G+E D
Sbjct: 172 HNKPGSFHCSCHSGFELSSD 191
Score = 60.5 bits (140), Expect = 2e-08
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 742 LDVFADVDECAAIPGLCAPGRFRCVCGPG--YRPAGEVCADVDECAVRPPPCDQLCHNTD 799
+D AD + C PG + C+C G Y + C DVDEC C+Q+C N+
Sbjct: 198 IDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECL--QGRCEQVCVNSP 255
Query: 800 GSYDCLC--RTGYELDEDGANCRDVDEC 825
GSY C C R G +L +D C D+ C
Sbjct: 256 GSYTCHCDGRGGLKLSQDMDTCEDILPC 283
>BX072579-3|CAH71174.1| 678|Homo sapiens growth arrest-specific 6
protein.
Length = 678
Score = 120 bits (288), Expect = 3e-26
Identities = 70/177 (39%), Positives = 88/177 (49%), Gaps = 20/177 (11%)
Query: 69 DECDIMPQLC-KPGT--CHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMA 124
D+C P C + GT C D F C C G+ LC +DV+ECS C +
Sbjct: 118 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGWG----GRLCDKDVNECSQENGGC--LQ 169
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPG--Y 182
C N PG+F C C G+ L+ C+D+DEC D C C+N GSY C C G Y
Sbjct: 170 ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAY 229
Query: 183 TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCD--DGFKAGPNND-CVDVNEC 236
+ +E CRDVDEC + R C C N PG+Y CHCD G K + D C D+ C
Sbjct: 230 SSQEKACRDVDECLQGR--CEQ-VCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 283
Score = 118 bits (285), Expect = 7e-26
Identities = 63/173 (36%), Positives = 89/173 (51%), Gaps = 16/173 (9%)
Query: 470 DECALDPRIC---GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHN 526
D+C +P C G C + G + C C G+ G DV+EC++ C CHN
Sbjct: 118 DQCTPNP--CDRKGTQACQDLMGNFFCLCKAGW--GGRLCDKDVNECSQENGGCLQICHN 173
Query: 527 TAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAP 586
GSF C+C G+ +++DG C+DIDEC C+N+ GSY C C EG+ +S
Sbjct: 174 KPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSS-- 231
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCD--AGFEPSEDGTDCID 637
E AC D++EC + C VC+N+ GS+ C CD G + S+D C D
Sbjct: 232 --QEKACRDVDEC--LQGRCE-QVCVNSPGSYTCHCDGRGGLKLSQDMDTCED 279
Score = 110 bits (265), Expect = 2e-23
Identities = 58/149 (38%), Positives = 74/149 (49%), Gaps = 7/149 (4%)
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
F +C+ G G +D++EC C+ C N GSF C C G+ L+ DG +C D
Sbjct: 140 FFCLCKAGWGGRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDI 198
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTFRCHNTA 528
DECA D CG C N G Y C C GF ++ C DVDEC +GR C C N+
Sbjct: 199 DECA-DSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGR--CEQVCVNSP 255
Query: 529 GSFRCTCP--YGYAVAADGVHCRDIDECV 555
GS+ C C G ++ D C DI CV
Sbjct: 256 GSYTCHCDGRGGLKLSQDMDTCEDILPCV 284
Score = 98.3 bits (234), Expect = 1e-19
Identities = 69/200 (34%), Positives = 89/200 (44%), Gaps = 20/200 (10%)
Query: 166 DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGT--CENLPGAYLCHCDDGFK 223
DC N GS + T +N+ D+C+ P P R GT C++L G + C C G+
Sbjct: 94 DCINKYGSPYTKNSGFATCVQNL---PDQCT-PNPCDRKGTQACQDLMGNFFCLCKAGW- 148
Query: 224 AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPH 283
G DVNEC + C C N GSF C C G+ L++DGR C+D+DEC +
Sbjct: 149 -GGRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECAD-SE 205
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYV 341
C G C N G Y C C G+ + C D DEC L C C N G Y
Sbjct: 206 AC---GEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC--LQGRCE-QVCVNSPGSYT 259
Query: 342 CECP--AGWRFDKTAAVCVD 359
C C G + + C D
Sbjct: 260 CHCDGRGGLKLSQDMDTCED 279
Score = 94.7 bits (225), Expect = 1e-18
Identities = 43/102 (42%), Positives = 59/102 (57%), Gaps = 7/102 (6%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G F C+C G+ G +C DV+EC+ C Q+CHN GS+ C C +G+EL DG C
Sbjct: 138 GNFFCLCKAGW--GGRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTC 195
Query: 820 RDVDECERDTHTCQQI-CSNTEGSYECSCEDG--YEKRGDAC 858
+D+DEC D+ C + C N GSY C C++G Y + AC
Sbjct: 196 QDIDEC-ADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKAC 236
Score = 89.4 bits (212), Expect = 5e-17
Identities = 44/110 (40%), Positives = 56/110 (50%), Gaps = 10/110 (9%)
Query: 747 DVDECAAIPGLCA------PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNT 798
DV+EC+ G C PG F C C G+ + G C D+DECA + C N
Sbjct: 156 DVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNL 215
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCE 848
GSY CLC G+ CRDVDEC + C+Q+C N+ GSY C C+
Sbjct: 216 PGSYSCLCDEGFAYSSQEKACRDVDECLQG--RCEQVCVNSPGSYTCHCD 263
Score = 64.9 bits (151), Expect = 1e-09
Identities = 32/80 (40%), Positives = 44/80 (55%), Gaps = 11/80 (13%)
Query: 782 DECAVRPPPCD----QLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQIC 836
D+C P PCD Q C + G++ CLC+ G+ G C +DV+EC ++ C QIC
Sbjct: 118 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGW----GGRLCDKDVNECSQENGGCLQIC 171
Query: 837 SNTEGSYECSCEDGYEKRGD 856
N GS+ CSC G+E D
Sbjct: 172 HNKPGSFHCSCHSGFELSSD 191
Score = 60.5 bits (140), Expect = 2e-08
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 742 LDVFADVDECAAIPGLCAPGRFRCVCGPG--YRPAGEVCADVDECAVRPPPCDQLCHNTD 799
+D AD + C PG + C+C G Y + C DVDEC C+Q+C N+
Sbjct: 198 IDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECL--QGRCEQVCVNSP 255
Query: 800 GSYDCLC--RTGYELDEDGANCRDVDEC 825
GSY C C R G +L +D C D+ C
Sbjct: 256 GSYTCHCDGRGGLKLSQDMDTCEDILPC 283
>BC038984-1|AAH38984.1| 678|Homo sapiens growth arrest-specific 6
protein.
Length = 678
Score = 120 bits (288), Expect = 3e-26
Identities = 70/177 (39%), Positives = 88/177 (49%), Gaps = 20/177 (11%)
Query: 69 DECDIMPQLC-KPGT--CHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMA 124
D+C P C + GT C D F C C G+ LC +DV+ECS C +
Sbjct: 118 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGWG----GRLCDKDVNECSQENGGC--LQ 169
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPG--Y 182
C N PG+F C C G+ L+ C+D+DEC D C C+N GSY C C G Y
Sbjct: 170 ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAY 229
Query: 183 TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCD--DGFKAGPNND-CVDVNEC 236
+ +E CRDVDEC + R C C N PG+Y CHCD G K + D C D+ C
Sbjct: 230 SSQEKACRDVDECLQGR--CEQ-VCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 283
Score = 118 bits (285), Expect = 7e-26
Identities = 63/173 (36%), Positives = 89/173 (51%), Gaps = 16/173 (9%)
Query: 470 DECALDPRIC---GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHN 526
D+C +P C G C + G + C C G+ G DV+EC++ C CHN
Sbjct: 118 DQCTPNP--CDRKGTQACQDLMGNFFCLCKAGW--GGRLCDKDVNECSQENGGCLQICHN 173
Query: 527 TAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAP 586
GSF C+C G+ +++DG C+DIDEC C+N+ GSY C C EG+ +S
Sbjct: 174 KPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSS-- 231
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCD--AGFEPSEDGTDCID 637
E AC D++EC + C VC+N+ GS+ C CD G + S+D C D
Sbjct: 232 --QEKACRDVDEC--LQGRCE-QVCVNSPGSYTCHCDGRGGLKLSQDMDTCED 279
Score = 110 bits (265), Expect = 2e-23
Identities = 58/149 (38%), Positives = 74/149 (49%), Gaps = 7/149 (4%)
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
F +C+ G G +D++EC C+ C N GSF C C G+ L+ DG +C D
Sbjct: 140 FFCLCKAGWGGRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDI 198
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTFRCHNTA 528
DECA D CG C N G Y C C GF ++ C DVDEC +GR C C N+
Sbjct: 199 DECA-DSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGR--CEQVCVNSP 255
Query: 529 GSFRCTCP--YGYAVAADGVHCRDIDECV 555
GS+ C C G ++ D C DI CV
Sbjct: 256 GSYTCHCDGRGGLKLSQDMDTCEDILPCV 284
Score = 98.3 bits (234), Expect = 1e-19
Identities = 69/200 (34%), Positives = 89/200 (44%), Gaps = 20/200 (10%)
Query: 166 DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGT--CENLPGAYLCHCDDGFK 223
DC N GS + T +N+ D+C+ P P R GT C++L G + C C G+
Sbjct: 94 DCINKYGSPYTKNSGFATCVQNL---PDQCT-PNPCDRKGTQACQDLMGNFFCLCKAGW- 148
Query: 224 AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPH 283
G DVNEC + C C N GSF C C G+ L++DGR C+D+DEC +
Sbjct: 149 -GGRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECAD-SE 205
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYV 341
C G C N G Y C C G+ + C D DEC L C C N G Y
Sbjct: 206 AC---GEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC--LQGRCE-QVCVNSPGSYT 259
Query: 342 CECP--AGWRFDKTAAVCVD 359
C C G + + C D
Sbjct: 260 CHCDGRGGLKLSQDMDTCED 279
Score = 94.7 bits (225), Expect = 1e-18
Identities = 43/102 (42%), Positives = 59/102 (57%), Gaps = 7/102 (6%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G F C+C G+ G +C DV+EC+ C Q+CHN GS+ C C +G+EL DG C
Sbjct: 138 GNFFCLCKAGW--GGRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTC 195
Query: 820 RDVDECERDTHTCQQI-CSNTEGSYECSCEDG--YEKRGDAC 858
+D+DEC D+ C + C N GSY C C++G Y + AC
Sbjct: 196 QDIDEC-ADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKAC 236
Score = 89.4 bits (212), Expect = 5e-17
Identities = 44/110 (40%), Positives = 56/110 (50%), Gaps = 10/110 (9%)
Query: 747 DVDECAAIPGLCA------PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNT 798
DV+EC+ G C PG F C C G+ + G C D+DECA + C N
Sbjct: 156 DVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNL 215
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCE 848
GSY CLC G+ CRDVDEC + C+Q+C N+ GSY C C+
Sbjct: 216 PGSYSCLCDEGFAYSSQEKACRDVDECLQG--RCEQVCVNSPGSYTCHCD 263
Score = 64.9 bits (151), Expect = 1e-09
Identities = 32/80 (40%), Positives = 44/80 (55%), Gaps = 11/80 (13%)
Query: 782 DECAVRPPPCD----QLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQIC 836
D+C P PCD Q C + G++ CLC+ G+ G C +DV+EC ++ C QIC
Sbjct: 118 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGW----GGRLCDKDVNECSQENGGCLQIC 171
Query: 837 SNTEGSYECSCEDGYEKRGD 856
N GS+ CSC G+E D
Sbjct: 172 HNKPGSFHCSCHSGFELSSD 191
Score = 60.5 bits (140), Expect = 2e-08
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 742 LDVFADVDECAAIPGLCAPGRFRCVCGPG--YRPAGEVCADVDECAVRPPPCDQLCHNTD 799
+D AD + C PG + C+C G Y + C DVDEC C+Q+C N+
Sbjct: 198 IDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECL--QGRCEQVCVNSP 255
Query: 800 GSYDCLC--RTGYELDEDGANCRDVDEC 825
GSY C C R G +L +D C D+ C
Sbjct: 256 GSYTCHCDGRGGLKLSQDMDTCEDILPC 283
>AY256843-1|AAO84057.1| 678|Homo sapiens growth arrested-specific 6
protein.
Length = 678
Score = 120 bits (288), Expect = 3e-26
Identities = 70/177 (39%), Positives = 88/177 (49%), Gaps = 20/177 (11%)
Query: 69 DECDIMPQLC-KPGT--CHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMA 124
D+C P C + GT C D F C C G+ LC +DV+ECS C +
Sbjct: 118 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGWG----GRLCDKDVNECSQENGGC--LQ 169
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPG--Y 182
C N PG+F C C G+ L+ C+D+DEC D C C+N GSY C C G Y
Sbjct: 170 ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAY 229
Query: 183 TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCD--DGFKAGPNND-CVDVNEC 236
+ +E CRDVDEC + R C C N PG+Y CHCD G K + D C D+ C
Sbjct: 230 SSQEKACRDVDECLQGR--CEQ-VCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 283
Score = 118 bits (285), Expect = 7e-26
Identities = 63/173 (36%), Positives = 89/173 (51%), Gaps = 16/173 (9%)
Query: 470 DECALDPRIC---GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHN 526
D+C +P C G C + G + C C G+ G DV+EC++ C CHN
Sbjct: 118 DQCTPNP--CDRKGTQACQDLMGNFFCLCKAGW--GGRLCDKDVNECSQENGGCLQICHN 173
Query: 527 TAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAP 586
GSF C+C G+ +++DG C+DIDEC C+N+ GSY C C EG+ +S
Sbjct: 174 KPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSS-- 231
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCD--AGFEPSEDGTDCID 637
E AC D++EC + C VC+N+ GS+ C CD G + S+D C D
Sbjct: 232 --QEKACRDVDEC--LQGRCE-QVCVNSPGSYTCHCDGRGGLKLSQDMDTCED 279
Score = 110 bits (265), Expect = 2e-23
Identities = 58/149 (38%), Positives = 74/149 (49%), Gaps = 7/149 (4%)
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
F +C+ G G +D++EC C+ C N GSF C C G+ L+ DG +C D
Sbjct: 140 FFCLCKAGWGGRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDI 198
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTFRCHNTA 528
DECA D CG C N G Y C C GF ++ C DVDEC +GR C C N+
Sbjct: 199 DECA-DSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGR--CEQVCVNSP 255
Query: 529 GSFRCTCP--YGYAVAADGVHCRDIDECV 555
GS+ C C G ++ D C DI CV
Sbjct: 256 GSYTCHCDGRGGLKLSQDMDTCEDILPCV 284
Score = 98.3 bits (234), Expect = 1e-19
Identities = 69/200 (34%), Positives = 89/200 (44%), Gaps = 20/200 (10%)
Query: 166 DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGT--CENLPGAYLCHCDDGFK 223
DC N GS + T +N+ D+C+ P P R GT C++L G + C C G+
Sbjct: 94 DCINKYGSPYTKNSGFATCVQNL---PDQCT-PNPCDRKGTQACQDLMGNFFCLCKAGW- 148
Query: 224 AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPH 283
G DVNEC + C C N GSF C C G+ L++DGR C+D+DEC +
Sbjct: 149 -GGRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECAD-SE 205
Query: 284 PCGRDGNPSCTNTNGGYECSCGAGWKLVG--RRCVDRDECKELPYVCAGGECRNFNGGYV 341
C G C N G Y C C G+ + C D DEC L C C N G Y
Sbjct: 206 AC---GEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC--LQGRCE-QVCVNSPGSYT 259
Query: 342 CECP--AGWRFDKTAAVCVD 359
C C G + + C D
Sbjct: 260 CHCDGRGGLKLSQDMDTCED 279
Score = 94.7 bits (225), Expect = 1e-18
Identities = 43/102 (42%), Positives = 59/102 (57%), Gaps = 7/102 (6%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G F C+C G+ G +C DV+EC+ C Q+CHN GS+ C C +G+EL DG C
Sbjct: 138 GNFFCLCKAGW--GGRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTC 195
Query: 820 RDVDECERDTHTCQQI-CSNTEGSYECSCEDG--YEKRGDAC 858
+D+DEC D+ C + C N GSY C C++G Y + AC
Sbjct: 196 QDIDEC-ADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKAC 236
Score = 89.4 bits (212), Expect = 5e-17
Identities = 44/110 (40%), Positives = 56/110 (50%), Gaps = 10/110 (9%)
Query: 747 DVDECAAIPGLCA------PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNT 798
DV+EC+ G C PG F C C G+ + G C D+DECA + C N
Sbjct: 156 DVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNL 215
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCE 848
GSY CLC G+ CRDVDEC + C+Q+C N+ GSY C C+
Sbjct: 216 PGSYSCLCDEGFAYSSQEKACRDVDECLQG--RCEQVCVNSPGSYTCHCD 263
Score = 64.9 bits (151), Expect = 1e-09
Identities = 32/80 (40%), Positives = 44/80 (55%), Gaps = 11/80 (13%)
Query: 782 DECAVRPPPCD----QLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQIC 836
D+C P PCD Q C + G++ CLC+ G+ G C +DV+EC ++ C QIC
Sbjct: 118 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGW----GGRLCDKDVNECSQENGGCLQIC 171
Query: 837 SNTEGSYECSCEDGYEKRGD 856
N GS+ CSC G+E D
Sbjct: 172 HNKPGSFHCSCHSGFELSSD 191
Score = 60.5 bits (140), Expect = 2e-08
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 742 LDVFADVDECAAIPGLCAPGRFRCVCGPG--YRPAGEVCADVDECAVRPPPCDQLCHNTD 799
+D AD + C PG + C+C G Y + C DVDEC C+Q+C N+
Sbjct: 198 IDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECL--QGRCEQVCVNSP 255
Query: 800 GSYDCLC--RTGYELDEDGANCRDVDEC 825
GSY C C R G +L +D C D+ C
Sbjct: 256 GSYTCHCDGRGGLKLSQDMDTCEDILPC 283
>AK126533-1|BAC86580.1| 624|Homo sapiens protein ( Homo sapiens
cDNA FLJ44569 fis, clone UTERU3009979, highly similar
to Homo sapiens growth arrest-specific 6 (GAS6). ).
Length = 624
Score = 120 bits (288), Expect = 3e-26
Identities = 70/177 (39%), Positives = 88/177 (49%), Gaps = 20/177 (11%)
Query: 69 DECDIMPQLC-KPGT--CHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMA 124
D+C P C + GT C D F C C G+ LC +DV+ECS C +
Sbjct: 64 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGWG----GRLCDKDVNECSQENGGC--LQ 115
Query: 125 QCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPG--Y 182
C N PG+F C C G+ L+ C+D+DEC D C C+N GSY C C G Y
Sbjct: 116 ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAY 175
Query: 183 TLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCD--DGFKAGPNND-CVDVNEC 236
+ +E CRDVDEC + R C C N PG+Y CHCD G K + D C D+ C
Sbjct: 176 SSQEKACRDVDECLQGR--CEQ-VCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 229
Score = 118 bits (285), Expect = 7e-26
Identities = 63/173 (36%), Positives = 89/173 (51%), Gaps = 16/173 (9%)
Query: 470 DECALDPRIC---GNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHN 526
D+C +P C G C + G + C C G+ G DV+EC++ C CHN
Sbjct: 64 DQCTPNP--CDRKGTQACQDLMGNFFCLCKAGW--GGRLCDKDVNECSQENGGCLQICHN 119
Query: 527 TAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAP 586
GSF C+C G+ +++DG C+DIDEC C+N+ GSY C C EG+ +S
Sbjct: 120 KPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSS-- 177
Query: 587 QDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCD--AGFEPSEDGTDCID 637
E AC D++EC + C VC+N+ GS+ C CD G + S+D C D
Sbjct: 178 --QEKACRDVDEC--LQGRCE-QVCVNSPGSYTCHCDGRGGLKLSQDMDTCED 225
Score = 110 bits (265), Expect = 2e-23
Identities = 58/149 (38%), Positives = 74/149 (49%), Gaps = 7/149 (4%)
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDA 469
F +C+ G G +D++EC C+ C N GSF C C G+ L+ DG +C D
Sbjct: 86 FFCLCKAGWGGRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDI 144
Query: 470 DECALDPRICGNGTCSNTRGGYECQCSPGFT-QGPDQTCVDVDECAEGRASCTFRCHNTA 528
DECA D CG C N G Y C C GF ++ C DVDEC +GR C C N+
Sbjct: 145 DECA-DSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGR--CEQVCVNSP 201
Query: 529 GSFRCTCP--YGYAVAADGVHCRDIDECV 555
GS+ C C G ++ D C DI CV
Sbjct: 202 GSYTCHCDGRGGLKLSQDMDTCEDILPCV 230
Score = 96.7 bits (230), Expect = 3e-19
Identities = 62/173 (35%), Positives = 79/173 (45%), Gaps = 17/173 (9%)
Query: 193 DECSRPRPVCRNGT--CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRN 250
D+C+ P P R GT C++L G + C C G+ G DVNEC + C C N
Sbjct: 64 DQCT-PNPCDRKGTQACQDLMGNFFCLCKAGW--GGRLCDKDVNECSQENGGCLQ-ICHN 119
Query: 251 TVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKL 310
GSF C C G+ L++DGR C+D+DEC + C G C N G Y C C G+
Sbjct: 120 KPGSFHCSCHSGFELSSDGRTCQDIDECAD-SEAC---GEARCKNLPGSYSCLCDEGFAY 175
Query: 311 VG--RRCVDRDECKELPYVCAGGECRNFNGGYVCECP--AGWRFDKTAAVCVD 359
+ C D DEC L C C N G Y C C G + + C D
Sbjct: 176 SSQEKACRDVDEC--LQGRCE-QVCVNSPGSYTCHCDGRGGLKLSQDMDTCED 225
Score = 94.7 bits (225), Expect = 1e-18
Identities = 43/102 (42%), Positives = 59/102 (57%), Gaps = 7/102 (6%)
Query: 761 GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G F C+C G+ G +C DV+EC+ C Q+CHN GS+ C C +G+EL DG C
Sbjct: 84 GNFFCLCKAGW--GGRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTC 141
Query: 820 RDVDECERDTHTCQQI-CSNTEGSYECSCEDG--YEKRGDAC 858
+D+DEC D+ C + C N GSY C C++G Y + AC
Sbjct: 142 QDIDEC-ADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKAC 182
Score = 89.4 bits (212), Expect = 5e-17
Identities = 44/110 (40%), Positives = 56/110 (50%), Gaps = 10/110 (9%)
Query: 747 DVDECAAIPGLCA------PGRFRCVCGPGYRPA--GEVCADVDECAVRPPPCDQLCHNT 798
DV+EC+ G C PG F C C G+ + G C D+DECA + C N
Sbjct: 102 DVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNL 161
Query: 799 DGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCE 848
GSY CLC G+ CRDVDEC + C+Q+C N+ GSY C C+
Sbjct: 162 PGSYSCLCDEGFAYSSQEKACRDVDECLQG--RCEQVCVNSPGSYTCHCD 209
Score = 64.9 bits (151), Expect = 1e-09
Identities = 32/80 (40%), Positives = 44/80 (55%), Gaps = 11/80 (13%)
Query: 782 DECAVRPPPCD----QLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQIC 836
D+C P PCD Q C + G++ CLC+ G+ G C +DV+EC ++ C QIC
Sbjct: 64 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGW----GGRLCDKDVNECSQENGGCLQIC 117
Query: 837 SNTEGSYECSCEDGYEKRGD 856
N GS+ CSC G+E D
Sbjct: 118 HNKPGSFHCSCHSGFELSSD 137
Score = 60.5 bits (140), Expect = 2e-08
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 742 LDVFADVDECAAIPGLCAPGRFRCVCGPG--YRPAGEVCADVDECAVRPPPCDQLCHNTD 799
+D AD + C PG + C+C G Y + C DVDEC C+Q+C N+
Sbjct: 144 IDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECL--QGRCEQVCVNSP 201
Query: 800 GSYDCLC--RTGYELDEDGANCRDVDEC 825
GSY C C R G +L +D C D+ C
Sbjct: 202 GSYTCHCDGRGGLKLSQDMDTCEDILPC 229
>AC013451-1|AAF87081.1| 969|Homo sapiens LTBP-2 protein.
Length = 969
Score = 119 bits (287), Expect = 4e-26
Identities = 55/134 (41%), Positives = 74/134 (55%), Gaps = 6/134 (4%)
Query: 61 VTNETKPIDECDI-MPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPP 119
VT T ID C +C PGTC + P G++C C GY+ + C D +EC R P
Sbjct: 838 VTLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECL--RDP 895
Query: 120 CRGMAQCVNLPGAFECRCPPGYRLTPS--LDECEDVDECGDQRICDHGDCRNTIGSYRCE 177
C+G +C+N G++ C C PGY L S EC+D++EC +C G C NT GSY CE
Sbjct: 896 CKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCE 955
Query: 178 CKPGYTL-RENVCR 190
C GY + R+ C+
Sbjct: 956 CDQGYIMVRKGHCQ 969
Score = 109 bits (261), Expect = 5e-23
Identities = 50/117 (42%), Positives = 63/117 (53%), Gaps = 5/117 (4%)
Query: 110 VDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRN 169
+D C+ G G CVNLP + C C PGY+L PS C D +EC G C N
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCIN 904
Query: 170 TIGSYRCECKPGYTLREN----VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
+GSY C C PGYTL + C+D++EC +P VC G C N G+Y C CD G+
Sbjct: 905 RVGSYSCFCYPGYTLATSGATQECQDINECEQP-GVCSGGQCTNTEGSYHCECDQGY 960
Score = 103 bits (247), Expect = 3e-21
Identities = 51/130 (39%), Positives = 63/130 (48%), Gaps = 6/130 (4%)
Query: 424 TQDLDECRV-RPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNG 482
T +D C +VC G CVN +RC C GY L P C D +EC DP G G
Sbjct: 842 TPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDP-CKGKG 900
Query: 483 TCSNTRGGYECQCSPGF---TQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGY 539
C N G Y C C PG+ T G Q C D++EC + +C NT GS+ C C GY
Sbjct: 901 RCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGY 960
Query: 540 AVAADGVHCR 549
+ G HC+
Sbjct: 961 IMVRKG-HCQ 969
Score = 103 bits (247), Expect = 3e-21
Identities = 52/131 (39%), Positives = 65/131 (49%), Gaps = 11/131 (8%)
Query: 144 TPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLREN--VCRDVDECSRPRPV 201
TP +D C G +C G C N YRC C PGY L + C D +EC R P
Sbjct: 842 TPGIDRCA----AGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRD-PC 896
Query: 202 CRNGTCENLPGAYLCHCDDGFK---AGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCE 258
G C N G+Y C C G+ +G +C D+NEC + G VC G+C NT GS+ CE
Sbjct: 897 KGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPG-VCSGGQCTNTEGSYHCE 955
Query: 259 CAPGYTLTADG 269
C GY + G
Sbjct: 956 CDQGYIMVRKG 966
Score = 102 bits (245), Expect = 5e-21
Identities = 50/119 (42%), Positives = 66/119 (55%), Gaps = 5/119 (4%)
Query: 510 VDECAEGRAS-C-TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN 567
+D CA G + C C N +RC C GY + +C D +EC+++P C N
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCIN 904
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
VGSY C C GY T A + C+DINEC EQ +CSGG C NT+GS+ C+CD G+
Sbjct: 905 RVGSYSCFCYPGY--TLATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECDQGY 960
Score = 101 bits (242), Expect = 1e-20
Identities = 52/125 (41%), Positives = 67/125 (53%), Gaps = 11/125 (8%)
Query: 192 VDECSRPRP-VCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVNECREGGMVCRN-GRC 248
+D C+ VC GTC NLP Y C C G++ P+ C D NEC C+ GRC
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDP--CKGKGRC 902
Query: 249 RNTVGSFRCECAPGYTLTADG--RNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGA 306
N VGS+ C C PGYTL G + C+D++EC++ P C CTNT G Y C C
Sbjct: 903 INRVGSYSCFCYPGYTLATSGATQECQDINECEQ-PGVCS---GGQCTNTEGSYHCECDQ 958
Query: 307 GWKLV 311
G+ +V
Sbjct: 959 GYIMV 963
Score = 93.5 bits (222), Expect = 3e-18
Identities = 49/116 (42%), Positives = 60/116 (51%), Gaps = 12/116 (10%)
Query: 748 VDECAAI------PGLCA--PGRFRCVCGPGYR--PAGEVCADVDECAVRPPPCDQLCHN 797
+D CAA PG C P +RCVC PGY+ P+ C D +EC P C N
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCIN 904
Query: 798 TDGSYDCLCRTGYELDEDGAN--CRDVDECERDTHTCQQICSNTEGSYECSCEDGY 851
GSY C C GY L GA C+D++ECE+ C+NTEGSY C C+ GY
Sbjct: 905 RVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGY 960
Score = 90.2 bits (214), Expect = 3e-17
Identities = 48/121 (39%), Positives = 59/121 (48%), Gaps = 10/121 (8%)
Query: 233 VNECREGGM-VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNP 291
++ C G VC G C N +RC C+PGY L C D +EC L PC G
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNEC--LRDPC--KGKG 900
Query: 292 SCTNTNGGYECSCGAGWKL----VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAG 347
C N G Y C C G+ L + C D +EC E P VC+GG+C N G Y CEC G
Sbjct: 901 RCINRVGSYSCFCYPGYTLATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECDQG 959
Query: 348 W 348
+
Sbjct: 960 Y 960
Score = 85.8 bits (203), Expect = 6e-16
Identities = 65/193 (33%), Positives = 83/193 (43%), Gaps = 18/193 (9%)
Query: 246 GRCR-NTVGSFRCECA-PGYTLTADGRNCRDVDEC--DELPHPCG-RDGNPSCTNTNGGY 300
GRC NTV +CA P LT C V L PC R +P N G
Sbjct: 552 GRCYLNTVNG---QCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIEN--GQL 606
Query: 301 ECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
EC G +L C D +EC L +C EC N G Y+C C G D + + CV +
Sbjct: 607 ECPQGYK-RLNLTHCQDINECLTLG-LCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSD 664
Query: 361 R-----KELCYDEWEAGRCHRARPLQLARPECCCSE-GAAWGRYCERCPAPDSAEFMRIC 414
+ + LCY G C ++ + CCCS G AWG CE+CP P + F IC
Sbjct: 665 KAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREIC 724
Query: 415 QGGMGRPNLTQDL 427
G G + D+
Sbjct: 725 PAGHGYTYASSDI 737
Score = 85.4 bits (202), Expect = 8e-16
Identities = 53/159 (33%), Positives = 71/159 (44%), Gaps = 32/159 (20%)
Query: 562 PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCD 621
P V+ + +CP+GY+R + C+DINEC LC C+NT GS+LC
Sbjct: 594 PRPASPVIENGQLECPQGYKRLNLTH-----CQDINECLTL-GLCKDAECVNTRGSYLCT 647
Query: 622 CDAGFEPSEDGTDCIDRRT-----GTCYRSLVSGRCEPEXXXXXXXXXXXXXXXXXXXXX 676
C G + C+ + G CYRSL G C
Sbjct: 648 CRPGLMLDPSRSRCVSDKAISMLQGLCYRSLGPGTC--------------------TLPL 687
Query: 677 XGHVTKAQCCCT-LGAAWGSECELCPAPGSPARLDLCTA 714
+TK CCC+ +G AWGSECE CP PG+ A ++C A
Sbjct: 688 AQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREICPA 726
Score = 65.3 bits (152), Expect = 9e-10
Identities = 48/134 (35%), Positives = 63/134 (47%), Gaps = 16/134 (11%)
Query: 365 CYDEWEAGRCHRARPL-QLARPECCC-SEGAAWG-RYCERCPAPDSAEFMRI----CQGG 417
CY G+C A PL +L E CC S GA WG C CP ++ + C G
Sbjct: 554 CYLNTVNGQC--ANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQG 611
Query: 418 MGRPNLT--QDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALD 475
R NLT QD++EC + +C CVNT GS+ C C G +L P CV ++
Sbjct: 612 YKRLNLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISML 670
Query: 476 PRIC----GNGTCS 485
+C G GTC+
Sbjct: 671 QGLCYRSLGPGTCT 684
Score = 53.6 bits (123), Expect = 3e-06
Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Query: 134 ECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVD 193
+ CP GY+ +L C+D++EC +C +C NT GSY C C+PG L + R V
Sbjct: 605 QLECPQGYKRL-NLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVS 663
Query: 194 E 194
+
Sbjct: 664 D 664
Score = 52.4 bits (120), Expect = 7e-06
Identities = 39/140 (27%), Positives = 53/140 (37%), Gaps = 13/140 (9%)
Query: 452 ECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVD 511
ECP GY + C D +EC L +C + C NTRG Y C C PG P ++
Sbjct: 607 ECPQGYKRL-NLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRS----- 659
Query: 512 ECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDIDEC-VQEPRVCPHACENV 568
C +A + C+ + G CT P + C + + E CP
Sbjct: 660 RCVSDKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEA 719
Query: 569 VGSYICKCPEGYRRTSAPQD 588
CP G+ T A D
Sbjct: 720 FREI---CPAGHGYTYASSD 736
Score = 51.2 bits (117), Expect = 2e-05
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 9/113 (7%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDEC-SWGRPPCRGMAQCVNLPGAFECR 136
C P Q C GY+ N +H C+D++EC + G C+ A+CVN G++ C
Sbjct: 592 CPPRPASPVIENGQLECPQGYKRLNLTH-CQDINECLTLGL--CKD-AECVNTRGSYLCT 647
Query: 137 CPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVC 189
C PG L PS C V + + G C ++G C + + +C
Sbjct: 648 CRPGLMLDPSRSRC--VSDKAISML--QGLCYRSLGPGTCTLPLAQRITKQIC 696
Score = 50.0 bits (114), Expect = 4e-05
Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 2/78 (2%)
Query: 218 CDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDE 277
C G+K C D+NEC G+ C++ C NT GS+ C C PG L C
Sbjct: 608 CPQGYKRLNLTHCQDINECLTLGL-CKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKA 666
Query: 278 CDELPHPCGRDGNP-SCT 294
L C R P +CT
Sbjct: 667 ISMLQGLCYRSLGPGTCT 684
Score = 49.2 bits (112), Expect = 6e-05
Identities = 34/92 (36%), Positives = 41/92 (44%), Gaps = 11/92 (11%)
Query: 551 IDECVQ-EPRVC-PHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSG 608
ID C VC P C N+ Y C C GY+ S+ C D NEC D C G
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQL----HPSQAYCTDDNEC--LRDPCKG 898
Query: 609 -GVCINTDGSFLCDCDAGFEPSEDGT--DCID 637
G CIN GS+ C C G+ + G +C D
Sbjct: 899 KGRCINRVGSYSCFCYPGYTLATSGATQECQD 930
Score = 49.2 bits (112), Expect = 6e-05
Identities = 37/139 (26%), Positives = 52/139 (37%), Gaps = 29/139 (20%)
Query: 327 VCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPE 386
VC G C N GY C C G++ + A C D+ + L GRC ++
Sbjct: 855 VCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCIN----RVGSYS 910
Query: 387 CCCSEG--AAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVN 444
C C G A + C + E +C G G+C N
Sbjct: 911 CFCYPGYTLATSGATQECQDINECEQPGVCSG-----------------------GQCTN 947
Query: 445 TDGSFRCECPDGYVLAPDG 463
T+GS+ CEC GY++ G
Sbjct: 948 TEGSYHCECDQGYIMVRKG 966
Score = 47.6 bits (108), Expect = 2e-04
Identities = 44/152 (28%), Positives = 57/152 (37%), Gaps = 9/152 (5%)
Query: 4 NEEDQSCAGAVGVPQTKYLCCCSVGHAWGAP-CEACPPR-GSPAHTALCGEKPGEYINPV 61
N + CA + T+ CC SVG WG C CPPR SP E P Y
Sbjct: 557 NTVNGQCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQGYKRLN 616
Query: 62 TNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCR 121
+ I+EC + LCK C +T + C C G D + C S +
Sbjct: 617 LTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISM----LQ 671
Query: 122 GMAQCVNLPGAFECRCPPGYRLTPSLDECEDV 153
G+ C G C P R+T + C V
Sbjct: 672 GL--CYRSLGPGTCTLPLAQRITKQICCCSRV 701
Score = 45.6 bits (103), Expect = 8e-04
Identities = 24/61 (39%), Positives = 31/61 (50%), Gaps = 6/61 (9%)
Query: 761 GRFRCVCGPGYR----PAGEVCADVDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 815
G + C C PGY A + C D++EC +P C C NT+GSY C C GY +
Sbjct: 907 GSYSCFCYPGYTLATSGATQECQDINECE-QPGVCSGGQCTNTEGSYHCECDQGYIMVRK 965
Query: 816 G 816
G
Sbjct: 966 G 966
Score = 44.0 bits (99), Expect = 0.002
Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 13/115 (11%)
Query: 177 ECKPGYT-LRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNND-CVDVN 234
EC GY L C+D++EC +C++ C N G+YLC C G P+ CV
Sbjct: 607 ECPQGYKRLNLTHCQDINECLT-LGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVS-- 663
Query: 235 ECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDV-----DECDELPHP 284
+ + G C ++G C +T C V EC++ P P
Sbjct: 664 ---DKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLP 715
Score = 41.5 bits (93), Expect = 0.012
Identities = 21/54 (38%), Positives = 25/54 (46%), Gaps = 1/54 (1%)
Query: 767 CGPGYRPAGEV-CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
C GY+ C D++EC D C NT GSY C CR G LD + C
Sbjct: 608 CPQGYKRLNLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRC 661
Score = 34.7 bits (76), Expect = 1.4
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 8/69 (11%)
Query: 784 CAVRPP-PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI-CSNTEG 841
CA PP P + N G +C GY+ + +C+D++EC C+ C NT G
Sbjct: 589 CAPCPPRPASPVIEN--GQLEC--PQGYKR-LNLTHCQDINEC-LTLGLCKDAECVNTRG 642
Query: 842 SYECSCEDG 850
SY C+C G
Sbjct: 643 SYLCTCRPG 651
>AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein.
Length = 723
Score = 117 bits (282), Expect = 2e-25
Identities = 96/317 (30%), Positives = 136/317 (42%), Gaps = 37/317 (11%)
Query: 38 CPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHG 97
C P H C +KPGE V + + DEC P C GTC +QC C G
Sbjct: 226 CLPGCDEQH-GFC-DKPGECKCRVGWQGRYCDECIRYPG-CLHGTCQQP---WQCNCQEG 279
Query: 98 YEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNL-PGAFECRCPPGYRLTPSLDECEDVDE 155
+ C +D++ C+ +P C+ A C N G++ C C PGY T + E +DE
Sbjct: 280 WG----GLFCNQDLNYCTHHKP-CKNGATCTNTGQGSYTCSCRPGY--TGATCEL-GIDE 331
Query: 156 CGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLP-GAY 214
C + G C + SY C C PG+ +C P G C + P G Y
Sbjct: 332 CDPSPCKNGGSCTDLENSYSCTCPPGF--YGKICELSAMTCADGPCFNGGRCSDSPDGGY 389
Query: 215 LCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCR 273
C C G+ +G N + ++ C C NG +C + ++ C C G++ GR+C
Sbjct: 390 SCRCPVGY-SGFNCE-KKIDYC--SSSPCSNGAKCVDLGDAYLCRCQAGFS----GRHCD 441
Query: 274 D-VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGG 331
D VD+C PC G +C + + C+C G+ GR C C+ P G
Sbjct: 442 DNVDDC--ASSPCANGG--TCRDGVNDFSCTCPPGY--TGRNCSAPVSRCEHAP-CHNGA 494
Query: 332 ECRNFNGGYVCECPAGW 348
C GYVCEC G+
Sbjct: 495 TCHERGHGYVCECARGY 511
Score = 97.5 bits (232), Expect = 2e-19
Identities = 88/330 (26%), Positives = 127/330 (38%), Gaps = 64/330 (19%)
Query: 301 ECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
EC C GW+ GR C DEC P C G C+ + C C GW C
Sbjct: 242 ECKCRVGWQ--GRYC---DECIRYPG-CLHGTCQQ---PWQCNCQEGWG----GLFC--- 285
Query: 361 RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGR 420
++L Y C +P C GA C + C+ G
Sbjct: 286 NQDLNY-------CTHHKP---------CKNGAT-------CTNTGQGSYTCSCRPGYTG 322
Query: 421 PNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRI 478
+DEC P C GG C + + S+ C CP G+ G C + A CA P
Sbjct: 323 ATCELGIDECD--PSPCKNGGSCTDLENSYSCTCPPGFY----GKICELSAMTCADGPCF 376
Query: 479 CGNGTCSNT-RGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPY 537
G G CS++ GGY C+C G++ + +D C+ S +C + ++ C C
Sbjct: 377 NG-GRCSDSPDGGYSCRCPVGYSGFNCEK--KIDYCSSSPCSNGAKCVDLGDAYLCRCQA 433
Query: 538 GYAVAADGVHCRD-IDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDI 596
G++ G HC D +D+C P C + V + C CP GY N +
Sbjct: 434 GFS----GRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGY-------TGRNCSAPV 482
Query: 597 NECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
+ C E +G C ++C+C G+
Sbjct: 483 SRC-EHAPCHNGATCHERGHGYVCECARGY 511
Score = 92.7 bits (220), Expect = 5e-18
Identities = 55/150 (36%), Positives = 71/150 (47%), Gaps = 16/150 (10%)
Query: 81 GTCHDTPTG-FQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
G C D+P G + C C GY N + +D CS PC A+CV+L A+ CRC
Sbjct: 379 GRCSDSPDGGYSCRCPVGYSGFNCE---KKIDYCS--SSPCSNGAKCVDLGDAYLCRCQA 433
Query: 140 GYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRP 198
G+ S C+D VD+C + G CR+ + + C C PGYT R N V C
Sbjct: 434 GF----SGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGR-NCSAPVSRCE-- 486
Query: 199 RPVCRNG-TCENLPGAYLCHCDDGFKAGPN 227
C NG TC Y+C C G+ GPN
Sbjct: 487 HAPCHNGATCHERGHGYVCECARGY-GGPN 515
Score = 44.0 bits (99), Expect = 0.002
Identities = 35/108 (32%), Positives = 44/108 (40%), Gaps = 18/108 (16%)
Query: 761 GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGA 817
G + C C PGY G C +DEC P PC C + + SY C C G+ G
Sbjct: 310 GSYTCSCRPGY--TGATCELGIDECD--PSPCKNGGSCTDLENSYSCTCPPGFY----GK 361
Query: 818 NCR-DVDECERDTHTCQQICSNT-EGSYECSCEDGY-----EKRGDAC 858
C C CS++ +G Y C C GY EK+ D C
Sbjct: 362 ICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYC 409
Score = 42.7 bits (96), Expect = 0.005
Identities = 27/96 (28%), Positives = 40/96 (41%), Gaps = 8/96 (8%)
Query: 761 GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G + C C GY +G C +D C+ P C + +Y C C+ G+ G +C
Sbjct: 387 GGYSCRCPVGY--SGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFS----GRHC 440
Query: 820 RD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
D VD+C C + + C+C GY R
Sbjct: 441 DDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGR 476
Score = 42.7 bits (96), Expect = 0.005
Identities = 28/91 (30%), Positives = 34/91 (37%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 820
+ C C G+ +G C D VD+CA P C + + C C GY G NC
Sbjct: 427 YLCRCQAGF--SGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGY----TGRNCSA 480
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
V CE C Y C C GY
Sbjct: 481 PVSRCEHAPCHNGATCHERGHGYVCECARGY 511
Score = 39.5 bits (88), Expect = 0.050
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 22/107 (20%)
Query: 751 CAAIPGLC-APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNT-DGSYDCLCRT 808
C G C PG C C G++ G C DEC +R P C H T + C C+
Sbjct: 230 CDEQHGFCDKPGE--CKCRVGWQ--GRYC---DEC-IRYPGC---LHGTCQQPWQCNCQE 278
Query: 809 GYELDEDGANC-RDVDECERDTHTCQQ--ICSNT-EGSYECSCEDGY 851
G+ G C +D++ C C+ C+NT +GSY CSC GY
Sbjct: 279 GW----GGLFCNQDLNYCTHHK-PCKNGATCTNTGQGSYTCSCRPGY 320
Score = 33.9 bits (74), Expect = 2.5
Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 16/86 (18%)
Query: 766 VCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC 825
VC PG++ G C + + P CD+ D +C CR G++ G C DEC
Sbjct: 211 VCNPGWK--GPYCTE----PICLPGCDEQHGFCDKPGECKCRVGWQ----GRYC---DEC 257
Query: 826 ERDTHTCQQICSNTEGSYECSCEDGY 851
R C + ++C+C++G+
Sbjct: 258 IRYPGCLHGTC---QQPWQCNCQEGW 280
Score = 32.3 bits (70), Expect = 7.5
Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 3/45 (6%)
Query: 63 NETKPIDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHL 106
N + P+ C+ P C G TCH+ G+ C C GY N L
Sbjct: 477 NCSAPVSRCEHAP--CHNGATCHERGHGYVCECARGYGGPNCQFL 519
>AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein.
Length = 723
Score = 117 bits (282), Expect = 2e-25
Identities = 96/317 (30%), Positives = 136/317 (42%), Gaps = 37/317 (11%)
Query: 38 CPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHG 97
C P H C +KPGE V + + DEC P C GTC +QC C G
Sbjct: 226 CLPGCDEQH-GFC-DKPGECKCRVGWQGRYCDECIRYPG-CLHGTCQQP---WQCNCQEG 279
Query: 98 YEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNL-PGAFECRCPPGYRLTPSLDECEDVDE 155
+ C +D++ C+ +P C+ A C N G++ C C PGY T + E +DE
Sbjct: 280 WG----GLFCNQDLNYCTHHKP-CKNGATCTNTGQGSYTCSCRPGY--TGATCEL-GIDE 331
Query: 156 CGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLP-GAY 214
C + G C + SY C C PG+ +C P G C + P G Y
Sbjct: 332 CDPSPCKNGGSCTDLENSYSCTCPPGF--YGKICELSAMTCADGPCFNGGRCSDSPDGGY 389
Query: 215 LCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCR 273
C C G+ +G N + ++ C C NG +C + ++ C C G++ GR+C
Sbjct: 390 SCRCPVGY-SGFNCE-KKIDYC--SSSPCSNGAKCVDLGDAYLCRCQAGFS----GRHCD 441
Query: 274 D-VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGG 331
D VD+C PC G +C + + C+C G+ GR C C+ P G
Sbjct: 442 DNVDDC--ASSPCANGG--TCRDGVNDFSCTCPPGY--TGRNCSAPVSRCEHAP-CHNGA 494
Query: 332 ECRNFNGGYVCECPAGW 348
C GYVCEC G+
Sbjct: 495 TCHERGHGYVCECARGY 511
Score = 97.5 bits (232), Expect = 2e-19
Identities = 88/330 (26%), Positives = 127/330 (38%), Gaps = 64/330 (19%)
Query: 301 ECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
EC C GW+ GR C DEC P C G C+ + C C GW C
Sbjct: 242 ECKCRVGWQ--GRYC---DECIRYPG-CLHGTCQQ---PWQCNCQEGWG----GLFC--- 285
Query: 361 RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGR 420
++L Y C +P C GA C + C+ G
Sbjct: 286 NQDLNY-------CTHHKP---------CKNGAT-------CTNTGQGSYTCSCRPGYTG 322
Query: 421 PNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRI 478
+DEC P C GG C + + S+ C CP G+ G C + A CA P
Sbjct: 323 ATCELGIDECD--PSPCKNGGSCTDLENSYSCTCPPGFY----GKICELSAMTCADGPCF 376
Query: 479 CGNGTCSNT-RGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPY 537
G G CS++ GGY C+C G++ + +D C+ S +C + ++ C C
Sbjct: 377 NG-GRCSDSPDGGYSCRCPVGYSGFNCEK--KIDYCSSSPCSNGAKCVDLGDAYLCRCQA 433
Query: 538 GYAVAADGVHCRD-IDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDI 596
G++ G HC D +D+C P C + V + C CP GY N +
Sbjct: 434 GFS----GRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGY-------TGRNCSAPV 482
Query: 597 NECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
+ C E +G C ++C+C G+
Sbjct: 483 SRC-EHAPCHNGATCHERGHGYVCECARGY 511
Score = 92.7 bits (220), Expect = 5e-18
Identities = 55/150 (36%), Positives = 71/150 (47%), Gaps = 16/150 (10%)
Query: 81 GTCHDTPTG-FQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
G C D+P G + C C GY N + +D CS PC A+CV+L A+ CRC
Sbjct: 379 GRCSDSPDGGYSCRCPVGYSGFNCE---KKIDYCS--SSPCSNGAKCVDLGDAYLCRCQA 433
Query: 140 GYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRP 198
G+ S C+D VD+C + G CR+ + + C C PGYT R N V C
Sbjct: 434 GF----SGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGR-NCSAPVSRCE-- 486
Query: 199 RPVCRNG-TCENLPGAYLCHCDDGFKAGPN 227
C NG TC Y+C C G+ GPN
Sbjct: 487 HAPCHNGATCHERGHGYVCECARGY-GGPN 515
Score = 44.0 bits (99), Expect = 0.002
Identities = 35/108 (32%), Positives = 44/108 (40%), Gaps = 18/108 (16%)
Query: 761 GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGA 817
G + C C PGY G C +DEC P PC C + + SY C C G+ G
Sbjct: 310 GSYTCSCRPGY--TGATCELGIDECD--PSPCKNGGSCTDLENSYSCTCPPGFY----GK 361
Query: 818 NCR-DVDECERDTHTCQQICSNT-EGSYECSCEDGY-----EKRGDAC 858
C C CS++ +G Y C C GY EK+ D C
Sbjct: 362 ICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYC 409
Score = 42.7 bits (96), Expect = 0.005
Identities = 27/96 (28%), Positives = 40/96 (41%), Gaps = 8/96 (8%)
Query: 761 GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G + C C GY +G C +D C+ P C + +Y C C+ G+ G +C
Sbjct: 387 GGYSCRCPVGY--SGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFS----GRHC 440
Query: 820 RD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
D VD+C C + + C+C GY R
Sbjct: 441 DDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGR 476
Score = 42.7 bits (96), Expect = 0.005
Identities = 28/91 (30%), Positives = 34/91 (37%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 820
+ C C G+ +G C D VD+CA P C + + C C GY G NC
Sbjct: 427 YLCRCQAGF--SGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGY----TGRNCSA 480
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
V CE C Y C C GY
Sbjct: 481 PVSRCEHAPCHNGATCHERGHGYVCECARGY 511
Score = 39.5 bits (88), Expect = 0.050
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 22/107 (20%)
Query: 751 CAAIPGLC-APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNT-DGSYDCLCRT 808
C G C PG C C G++ G C DEC +R P C H T + C C+
Sbjct: 230 CDEQHGFCDKPGE--CKCRVGWQ--GRYC---DEC-IRYPGC---LHGTCQQPWQCNCQE 278
Query: 809 GYELDEDGANC-RDVDECERDTHTCQQ--ICSNT-EGSYECSCEDGY 851
G+ G C +D++ C C+ C+NT +GSY CSC GY
Sbjct: 279 GW----GGLFCNQDLNYCTHHK-PCKNGATCTNTGQGSYTCSCRPGY 320
Score = 33.9 bits (74), Expect = 2.5
Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 16/86 (18%)
Query: 766 VCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC 825
VC PG++ G C + + P CD+ D +C CR G++ G C DEC
Sbjct: 211 VCNPGWK--GPYCTE----PICLPGCDEQHGFCDKPGECKCRVGWQ----GRYC---DEC 257
Query: 826 ERDTHTCQQICSNTEGSYECSCEDGY 851
R C + ++C+C++G+
Sbjct: 258 IRYPGCLHGTC---QQPWQCNCQEGW 280
Score = 32.3 bits (70), Expect = 7.5
Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 3/45 (6%)
Query: 63 NETKPIDECDIMPQLCKPG-TCHDTPTGFQCGCDHGYEHDNTSHL 106
N + P+ C+ P C G TCH+ G+ C C GY N L
Sbjct: 477 NCSAPVSRCEHAP--CHNGATCHERGHGYVCECARGYGGPNCQFL 519
>AK056571-1|BAB71219.1| 955|Homo sapiens protein ( Homo sapiens
cDNA FLJ32009 fis, clone NT2RP7009498, weakly similar to
FIBULIN-1, ISOFORM A PRECURSOR. ).
Length = 955
Score = 116 bits (279), Expect = 4e-25
Identities = 74/210 (35%), Positives = 94/210 (44%), Gaps = 24/210 (11%)
Query: 439 GGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRI---CGNGTCSNTRGGYECQ- 494
GG C SF C G +AP+ SC D ++ A P CG C T CQ
Sbjct: 63 GGHCTLPLCSFGCG--SGICIAPNVCSCQDGEQGATCPETHGPCGEYGCDLTCNHGGCQE 120
Query: 495 ----CSPGFTQGPDQT---CVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVH 547
C GF+ C D+DEC +SC C NT G F C C G ++AD
Sbjct: 121 VARVCPVGFSMTEAAVGIRCTDIDECVT--SSCEGHCVNTEGGFVCECGPGMQLSADRHS 178
Query: 548 CRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEE--QEDL 605
C+D DEC+ P C C+N +GSY C C G+ + ++C D+NEC + +
Sbjct: 179 CQDTDECLGTP--CQQRCKNSIGSYKCSCRTGFHL----HGNRHSCVDVNECRRPLERRV 232
Query: 606 CSGGVCINTDGSFLCDCDAGFEPSEDGTDC 635
C C NT GSFLC C GF D C
Sbjct: 233 CHHS-CHNTVGSFLCTCRPGFRLRADRVSC 261
Score = 110 bits (264), Expect = 2e-23
Identities = 60/136 (44%), Positives = 70/136 (51%), Gaps = 9/136 (6%)
Query: 426 DLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCS 485
D+DEC C G CVNT+G F CEC G L+ D SC D DEC P C C
Sbjct: 142 DIDECVTSS--CEG-HCVNTEGGFVCECGPGMQLSADRHSCQDTDECLGTP--C-QQRCK 195
Query: 486 NTRGGYECQCSPGF-TQGPDQTCVDVDECAE--GRASCTFRCHNTAGSFRCTCPYGYAVA 542
N+ G Y+C C GF G +CVDV+EC R C CHNT GSF CTC G+ +
Sbjct: 196 NSIGSYKCSCRTGFHLHGNRHSCVDVNECRRPLERRVCHHSCHNTVGSFLCTCRPGFRLR 255
Query: 543 ADGVHCRDIDECVQEP 558
AD V C + V P
Sbjct: 256 ADRVSCEAFPKAVLAP 271
Score = 101 bits (241), Expect = 1e-20
Identities = 52/121 (42%), Positives = 67/121 (55%), Gaps = 11/121 (9%)
Query: 107 CRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGD 166
C D+DEC C G CVN G F C C PG +L+ C+D DEC C
Sbjct: 140 CTDIDECVTSS--CEG--HCVNTEGGFVCECGPGMQLSADRHSCQDTDECLGTP-CQQ-R 193
Query: 167 CRNTIGSYRCECKPGYTLREN--VCRDVDECSRP--RPVCRNGTCENLPGAYLCHCDDGF 222
C+N+IGSY+C C+ G+ L N C DV+EC RP R VC + +C N G++LC C GF
Sbjct: 194 CKNSIGSYKCSCRTGFHLHGNRHSCVDVNECRRPLERRVCHH-SCHNTVGSFLCTCRPGF 252
Query: 223 K 223
+
Sbjct: 253 R 253
Score = 97.9 bits (233), Expect = 1e-19
Identities = 49/118 (41%), Positives = 64/118 (54%), Gaps = 10/118 (8%)
Query: 747 DVDEC--AAIPGLCA--PGRFRCVCGPGYRPAGE--VCADVDECAVRPPPCDQLCHNTDG 800
D+DEC ++ G C G F C CGPG + + + C D DEC PC Q C N+ G
Sbjct: 142 DIDECVTSSCEGHCVNTEGGFVCECGPGMQLSADRHSCQDTDECL--GTPCQQRCKNSIG 199
Query: 801 SYDCLCRTGYELDEDGANCRDVDECER--DTHTCQQICSNTEGSYECSCEDGYEKRGD 856
SY C CRTG+ L + +C DV+EC R + C C NT GS+ C+C G+ R D
Sbjct: 200 SYKCSCRTGFHLHGNRHSCVDVNECRRPLERRVCHHSCHNTVGSFLCTCRPGFRLRAD 257
Score = 97.5 bits (232), Expect = 2e-19
Identities = 59/162 (36%), Positives = 76/162 (46%), Gaps = 19/162 (11%)
Query: 202 CRNGTCENLPGAYLCHCDDGF---KAGPNNDCVDVNECREGGMVCRNGRCRNTVGSFRCE 258
C +G C+ + C GF +A C D++EC C G C NT G F CE
Sbjct: 113 CNHGGCQEVARV----CPVGFSMTEAAVGIRCTDIDECVTSS--CE-GHCVNTEGGFVCE 165
Query: 259 CAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR--CV 316
C PG L+AD +C+D DEC L PC C N+ G Y+CSC G+ L G R CV
Sbjct: 166 CGPGMQLSADRHSCQDTDEC--LGTPC----QQRCKNSIGSYKCSCRTGFHLHGNRHSCV 219
Query: 317 DRDECKE-LPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVC 357
D +EC+ L C N G ++C C G+R C
Sbjct: 220 DVNECRRPLERRVCHHSCHNTVGSFLCTCRPGFRLRADRVSC 261
Score = 92.7 bits (220), Expect = 5e-18
Identities = 47/121 (38%), Positives = 67/121 (55%), Gaps = 11/121 (9%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC + C+ G C +T GF C C G + H C+D DEC PC+ +C
Sbjct: 143 IDEC--VTSSCE-GHCVNTEGGFVCECGPGMQLSADRHSCQDTDECLG--TPCQ--QRCK 195
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECG---DQRICDHGDCRNTIGSYRCECKPGYTL 184
N G+++C C G+ L + C DV+EC ++R+C H C NT+GS+ C C+PG+ L
Sbjct: 196 NSIGSYKCSCRTGFHLHGNRHSCVDVNECRRPLERRVCHHS-CHNTVGSFLCTCRPGFRL 254
Query: 185 R 185
R
Sbjct: 255 R 255
Score = 77.8 bits (183), Expect = 2e-13
Identities = 61/198 (30%), Positives = 83/198 (41%), Gaps = 28/198 (14%)
Query: 202 CRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVN-ECREGG--MVCRNGRCRNTVGSFRCE 258
C +G C +C C DG + C + + C E G + C +G C+
Sbjct: 75 CGSGICI---APNVCSCQDGEQGAT---CPETHGPCGEYGCDLTCNHGGCQEVARV---- 124
Query: 259 CAPGYTLT--ADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR-- 314
C G+++T A G C D+DEC + C +G+ C NT GG+ C CG G +L R
Sbjct: 125 CPVGFSMTEAAVGIRCTDIDEC--VTSSC--EGH--CVNTEGGFVCECGPGMQLSADRHS 178
Query: 315 CVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC 374
C D DEC P C C+N G Y C C G+ CVD + C E C
Sbjct: 179 CQDTDECLGTP--CQQ-RCKNSIGSYKCSCRTGFHLHGNRHSCVDVNE--CRRPLERRVC 233
Query: 375 HRARPLQLARPECCCSEG 392
H + + C C G
Sbjct: 234 HHSCHNTVGSFLCTCRPG 251
Score = 74.9 bits (176), Expect = 1e-12
Identities = 65/225 (28%), Positives = 90/225 (40%), Gaps = 33/225 (14%)
Query: 431 RVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGG 490
R+ P VC+ G F C G+ + G C C+ CG+G C
Sbjct: 39 RLGPHVCLSG--------FGSGCCPGWAPSMGGGHCT-LPLCSFG---CGSGICIAPN-- 84
Query: 491 YECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC-HNTAGSFRCTCPYGYAV--AADGVH 547
C C G QG TC + G C C H CP G+++ AA G+
Sbjct: 85 -VCSCQDG-EQGA--TCPETHGPC-GEYGCDLTCNHGGCQEVARVCPVGFSMTEAAVGIR 139
Query: 548 CRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCS 607
C DIDECV C C N G ++C+C G + ++ ++C+D +EC C
Sbjct: 140 CTDIDECVTSS--CEGHCVNTEGGFVCECGPGMQLSA----DRHSCQDTDECLGTP--CQ 191
Query: 608 GGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTCYRSLVSGRC 652
C N+ GS+ C C GF + C+D C R L C
Sbjct: 192 QR-CKNSIGSYKCSCRTGFHLHGNRHSCVD--VNECRRPLERRVC 233
Score = 63.3 bits (147), Expect = 4e-09
Identities = 68/242 (28%), Positives = 91/242 (37%), Gaps = 45/242 (18%)
Query: 246 GRCRNTVGSFRCECAPGYTLTADGRNCRDVDE---CDELPHPCGRDGNPSCTNTNGGYEC 302
G C + SF C G + + +C+D ++ C E PCG G N G E
Sbjct: 64 GHCTLPLCSFGC--GSGICIAPNVCSCQDGEQGATCPETHGPCGEYGCDLTCNHGGCQEV 121
Query: 303 S--CGAGWKL----VGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAV 356
+ C G+ + VG RC D DEC + C G C N GG+VCEC G +
Sbjct: 122 ARVCPVGFSMTEAAVGIRCTDIDEC--VTSSCEG-HCVNTEGGFVCECGPGMQLSADRHS 178
Query: 357 CVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQG 416
C D DE C + + +C C G
Sbjct: 179 CQDT------DECLGTPCQQRCKNSIGSYKCSCRTGFHL--------------------- 211
Query: 417 GMGRPNLTQDLDECR--VRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCVDADECAL 474
G + D++ECR + VC C NT GSF C C G+ L D +SC + L
Sbjct: 212 -HGNRHSCVDVNECRRPLERRVC-HHSCHNTVGSFLCTCRPGFRLRADRVSCEAFPKAVL 269
Query: 475 DP 476
P
Sbjct: 270 AP 271
Score = 54.8 bits (126), Expect = 1e-06
Identities = 37/130 (28%), Positives = 53/130 (40%), Gaps = 9/130 (6%)
Query: 24 CCSVGHAWGAPCEACPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTC 83
C + + CE CG PG ++ + + DEC P C+ C
Sbjct: 140 CTDIDECVTSSCEGHCVNTEGGFVCECG--PGMQLSADRHSCQDTDECLGTP--CQQ-RC 194
Query: 84 HDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQ--CVNLPGAFECRCPPGY 141
++ ++C C G+ H C DV+EC RP R + C N G+F C C PG+
Sbjct: 195 KNSIGSYKCSCRTGFHLHGNRHSCVDVNECR--RPLERRVCHHSCHNTVGSFLCTCRPGF 252
Query: 142 RLTPSLDECE 151
RL CE
Sbjct: 253 RLRADRVSCE 262
Score = 54.8 bits (126), Expect = 1e-06
Identities = 32/82 (39%), Positives = 40/82 (48%), Gaps = 10/82 (12%)
Query: 747 DVDECAAIP--GLC--APGRFRCVCGPGYRPAGE--VCADVDECAVRPPP---CDQLCHN 797
D DEC P C + G ++C C G+ G C DV+EC RP C CHN
Sbjct: 181 DTDECLGTPCQQRCKNSIGSYKCSCRTGFHLHGNRHSCVDVNECR-RPLERRVCHHSCHN 239
Query: 798 TDGSYDCLCRTGYELDEDGANC 819
T GS+ C CR G+ L D +C
Sbjct: 240 TVGSFLCTCRPGFRLRADRVSC 261
Score = 52.4 bits (120), Expect = 7e-06
Identities = 42/150 (28%), Positives = 60/150 (40%), Gaps = 16/150 (10%)
Query: 513 CAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDE---CVQEPRVC-PHACENV 568
C G A H T C G +A + C+D ++ C + C + C+
Sbjct: 53 CCPGWAPSMGGGHCTLPLCSFGCGSGICIAPNVCSCQDGEQGATCPETHGPCGEYGCDLT 112
Query: 569 VGSYICK-----CPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCD 623
C+ CP G+ T A C DI+EC C G C+NT+G F+C+C
Sbjct: 113 CNHGGCQEVARVCPVGFSMTEAAVGIR--CTDIDECVTSS--CEGH-CVNTEGGFVCECG 167
Query: 624 AGFEPSEDGTDCIDRRTGTCYRSLVSGRCE 653
G + S D C D T C + RC+
Sbjct: 168 PGMQLSADRHSCQD--TDECLGTPCQQRCK 195
Score = 48.4 bits (110), Expect = 1e-04
Identities = 34/103 (33%), Positives = 46/103 (44%), Gaps = 15/103 (14%)
Query: 767 CGPGYRPAGEVCA--DVDECAVRPP---PCDQL-CHNTDGSYDC-----LCRTGYELDED 815
CG G A VC+ D ++ A P PC + C T C +C G+ + E
Sbjct: 75 CGSGICIAPNVCSCQDGEQGATCPETHGPCGEYGCDLTCNHGGCQEVARVCPVGFSMTEA 134
Query: 816 --GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD 856
G C D+DEC T +C+ C NTEG + C C G + D
Sbjct: 135 AVGIRCTDIDECV--TSSCEGHCVNTEGGFVCECGPGMQLSAD 175
>AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein
protein.
Length = 723
Score = 115 bits (276), Expect = 8e-25
Identities = 95/313 (30%), Positives = 134/313 (42%), Gaps = 37/313 (11%)
Query: 38 CPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHG 97
C P H C +KPGE V + + DEC P C GTC +QC C G
Sbjct: 226 CLPGCDEQH-GFC-DKPGECKCRVGWQGRYCDECIRYPG-CLHGTCQQP---WQCNCQEG 279
Query: 98 YEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNL-PGAFECRCPPGYRLTPSLDECEDVDE 155
+ C +D++ C+ +P C+ A C N G++ C C PGY T + E +DE
Sbjct: 280 WG----GLFCNQDLNYCTHHKP-CKNGATCTNTGQGSYTCSCRPGY--TGATCEL-GIDE 331
Query: 156 CGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLP-GAY 214
C + G C + SY C C PG+ +C P G C + P G Y
Sbjct: 332 CDPSPCKNGGSCTDLENSYSCTCPPGF--YGKICELSAMTCADGPCFNGGRCSDSPDGGY 389
Query: 215 LCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCR 273
C C G+ +G N + ++ C C NG +C + ++ C C G++ GR+C
Sbjct: 390 SCRCPVGY-SGFNCE-KKIDYC--SSSPCSNGAKCVDLGDAYLCRCQAGFS----GRHCD 441
Query: 274 D-VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGG 331
D VD+C PC G +C + + C+C G+ GR C C+ P G
Sbjct: 442 DNVDDC--ASSPCANGG--TCRDGVNDFSCTCPPGY--TGRNCSAPVSRCEHAP-CHNGA 494
Query: 332 ECRNFNGGYVCEC 344
C GYVCEC
Sbjct: 495 TCHQRGHGYVCEC 507
Score = 113 bits (271), Expect = 3e-24
Identities = 82/238 (34%), Positives = 105/238 (44%), Gaps = 31/238 (13%)
Query: 78 CKPG-TCHDTPTG-FQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFE 134
CK G TC +T G + C C GY T C +DEC PC+ C +L ++
Sbjct: 298 CKNGATCTNTGQGSYTCSCRPGY----TGATCELGIDECD--PSPCKNGGSCTDLENSYS 351
Query: 135 CRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNT-IGSYRCECKPGYTLRENVCRDVD 193
C CPPG+ + E + C D + G C ++ G Y C C GY+ N + +D
Sbjct: 352 CTCPPGF--YGKICELSAM-TCADGPCFNGGRCSDSPDGGYSCRCPVGYS-GFNCEKKID 407
Query: 194 ECSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNT 251
CS C NG C +L AYLC C GF +D VD +C C N G CR+
Sbjct: 408 YCS--SSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVD--DC--ASSPCANGGTCRDG 461
Query: 252 VGSFRCECAPGYTLTADGRNC-RDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
V F C C PGYT GRNC V C+ PC +C GY C C +
Sbjct: 462 VNDFSCTCPPGYT----GRNCSAPVSRCEHA--PC--HNGATCHQRGHGYVCECARSY 511
Score = 105 bits (251), Expect = 9e-22
Identities = 79/256 (30%), Positives = 110/256 (42%), Gaps = 39/256 (15%)
Query: 386 ECCCSEGAAW-GRYCERC-------PAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVC 437
EC C G W GRYC+ C + CQ G G QDL+ C
Sbjct: 242 ECKCRVG--WQGRYCDECIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCK 299
Query: 438 VGGRCVNT-DGSFRCECPDGYVLAPDGLSC-VDADECALDPRICGNG-TCSNTRGGYECQ 494
G C NT GS+ C C GY G +C + DEC DP C NG +C++ Y C
Sbjct: 300 NGATCTNTGQGSYTCSCRPGYT----GATCELGIDEC--DPSPCKNGGSCTDLENSYSCT 353
Query: 495 CSPGFTQGPDQTC-VDVDECAEGRASCTFRCHNTA-GSFRCTCPYGYAVAADGVHC-RDI 551
C PGF + C + CA+G RC ++ G + C CP GY+ G +C + I
Sbjct: 354 CPPGFY---GKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYS----GFNCEKKI 406
Query: 552 DECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACED-INECEEQEDLCSGGV 610
D C P C ++ +Y+C+C G+ S C+D +++C +GG
Sbjct: 407 DYCSSSPCSNGAKCVDLGDAYLCRCQAGF--------SGRHCDDNVDDCASSP-CANGGT 457
Query: 611 CINTDGSFLCDCDAGF 626
C + F C C G+
Sbjct: 458 CRDGVNDFSCTCPPGY 473
Score = 95.1 bits (226), Expect = 9e-19
Identities = 87/326 (26%), Positives = 125/326 (38%), Gaps = 64/326 (19%)
Query: 301 ECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
EC C GW+ GR C DEC P C G C+ + C C GW C
Sbjct: 242 ECKCRVGWQ--GRYC---DECIRYPG-CLHGTCQQ---PWQCNCQEGWG----GLFC--- 285
Query: 361 RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGR 420
++L Y C +P C GA C + C+ G
Sbjct: 286 NQDLNY-------CTHHKP---------CKNGAT-------CTNTGQGSYTCSCRPGYTG 322
Query: 421 PNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRI 478
+DEC P C GG C + + S+ C CP G+ G C + A CA P
Sbjct: 323 ATCELGIDECD--PSPCKNGGSCTDLENSYSCTCPPGFY----GKICELSAMTCADGPCF 376
Query: 479 CGNGTCSNT-RGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPY 537
G G CS++ GGY C+C G++ + +D C+ S +C + ++ C C
Sbjct: 377 NG-GRCSDSPDGGYSCRCPVGYSGFNCEK--KIDYCSSSPCSNGAKCVDLGDAYLCRCQA 433
Query: 538 GYAVAADGVHCRD-IDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDI 596
G++ G HC D +D+C P C + V + C CP GY N +
Sbjct: 434 GFS----GRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGY-------TGRNCSAPV 482
Query: 597 NECEEQEDLCSGGVCINTDGSFLCDC 622
+ C E +G C ++C+C
Sbjct: 483 SRC-EHAPCHNGATCHQRGHGYVCEC 507
Score = 90.2 bits (214), Expect = 3e-17
Identities = 54/150 (36%), Positives = 70/150 (46%), Gaps = 16/150 (10%)
Query: 81 GTCHDTPTG-FQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
G C D+P G + C C GY N + +D CS PC A+CV+L A+ CRC
Sbjct: 379 GRCSDSPDGGYSCRCPVGYSGFNCE---KKIDYCS--SSPCSNGAKCVDLGDAYLCRCQA 433
Query: 140 GYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRP 198
G+ S C+D VD+C + G CR+ + + C C PGYT R N V C
Sbjct: 434 GF----SGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGR-NCSAPVSRCE-- 486
Query: 199 RPVCRNG-TCENLPGAYLCHCDDGFKAGPN 227
C NG TC Y+C C + GPN
Sbjct: 487 HAPCHNGATCHQRGHGYVCECARSY-GGPN 515
Score = 44.0 bits (99), Expect = 0.002
Identities = 35/108 (32%), Positives = 44/108 (40%), Gaps = 18/108 (16%)
Query: 761 GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGA 817
G + C C PGY G C +DEC P PC C + + SY C C G+ G
Sbjct: 310 GSYTCSCRPGY--TGATCELGIDECD--PSPCKNGGSCTDLENSYSCTCPPGFY----GK 361
Query: 818 NCR-DVDECERDTHTCQQICSNT-EGSYECSCEDGY-----EKRGDAC 858
C C CS++ +G Y C C GY EK+ D C
Sbjct: 362 ICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYC 409
Score = 42.7 bits (96), Expect = 0.005
Identities = 27/96 (28%), Positives = 40/96 (41%), Gaps = 8/96 (8%)
Query: 761 GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G + C C GY +G C +D C+ P C + +Y C C+ G+ G +C
Sbjct: 387 GGYSCRCPVGY--SGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFS----GRHC 440
Query: 820 RD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
D VD+C C + + C+C GY R
Sbjct: 441 DDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGR 476
Score = 40.3 bits (90), Expect = 0.028
Identities = 27/91 (29%), Positives = 33/91 (36%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 820
+ C C G+ +G C D VD+CA P C + + C C GY G NC
Sbjct: 427 YLCRCQAGF--SGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGY----TGRNCSA 480
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
V CE C Y C C Y
Sbjct: 481 PVSRCEHAPCHNGATCHQRGHGYVCECARSY 511
Score = 39.5 bits (88), Expect = 0.050
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 22/107 (20%)
Query: 751 CAAIPGLC-APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNT-DGSYDCLCRT 808
C G C PG C C G++ G C DEC +R P C H T + C C+
Sbjct: 230 CDEQHGFCDKPGE--CKCRVGWQ--GRYC---DEC-IRYPGC---LHGTCQQPWQCNCQE 278
Query: 809 GYELDEDGANC-RDVDECERDTHTCQQ--ICSNT-EGSYECSCEDGY 851
G+ G C +D++ C C+ C+NT +GSY CSC GY
Sbjct: 279 GW----GGLFCNQDLNYCTHHK-PCKNGATCTNTGQGSYTCSCRPGY 320
Score = 33.9 bits (74), Expect = 2.5
Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 16/86 (18%)
Query: 766 VCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC 825
VC PG++ G C + + P CD+ D +C CR G++ G C DEC
Sbjct: 211 VCNPGWK--GPYCTE----PICLPGCDEQHGFCDKPGECKCRVGWQ----GRYC---DEC 257
Query: 826 ERDTHTCQQICSNTEGSYECSCEDGY 851
R C + ++C+C++G+
Sbjct: 258 IRYPGCLHGTC---QQPWQCNCQEGW 280
>AB208923-1|BAD92160.1| 441|Homo sapiens crumbs homolog 1 isoform
II precursor variant protein.
Length = 441
Score = 114 bits (275), Expect = 1e-24
Identities = 87/294 (29%), Positives = 132/294 (44%), Gaps = 33/294 (11%)
Query: 8 QSCAGAVGVP-QTKYLCCCSVGHAWGAPCE----ACPPRGSPAHTALCGEKP--GEYINP 60
Q A V P + +LC C G++ G CE +C + S H +C + P I P
Sbjct: 105 QGSATCVNTPGERSFLCKCPPGYS-GTICETTIGSCG-KNSCQHGGICHQDPIYPVCICP 162
Query: 61 VTNETK--PIDECDIMPQLCKPGT-CHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGR 117
+ ID + C+ G C D G+ C C GY+ H +VDEC+
Sbjct: 163 AGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQG---RHCDLEVDECA--S 217
Query: 118 PPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRC 176
PC+ A C+N G + C CP Y S CE ++DEC Q + C++ +G+Y C
Sbjct: 218 DPCKNEATCLNEIGRYTCICPHNY----SGVNCELEIDECWSQPCLNGATCQDALGAYFC 273
Query: 177 ECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNEC 236
+C PG+ L ++ + DEC+ +P G C + Y C+C G + C +
Sbjct: 274 DCAPGF-LGDHCELNTDECA-SQPCLHGGLCVDGENRYSCNCTGSGFTGTH--CETLMPL 329
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDG 289
N C ++V ++ C C PGYT G C D++EC+ +PC +G
Sbjct: 330 CWSKPCHNNATCEDSVDNYTCHCWPGYT----GAQCEIDLNECNS--NPCQSNG 377
Score = 111 bits (268), Expect = 8e-24
Identities = 91/274 (33%), Positives = 124/274 (45%), Gaps = 40/274 (14%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS--WGRPPCRGMAQCVNLPG--AFECRC 137
TC D C C D ++L +D D PC+G A CVN PG +F C+C
Sbjct: 69 TCKDFSKDNDCSCS-----DTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKC 123
Query: 138 PPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYR-CECKPGYTLRENVCR-DVDE 194
PPGY T CE + CG + C HG + Y C C GY R C D DE
Sbjct: 124 PPGYSGT----ICETTIGSCG-KNSCQHGGICHQDPIYPVCICPAGYAGR--FCEIDHDE 176
Query: 195 CSRPRPVCRNG-TCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTV 252
C+ C+NG C++ Y C C G++ G + D ++V+EC C+N C N +
Sbjct: 177 CA--SSPCQNGAVCQDGIDGYSCFCVPGYQ-GRHCD-LEVDECASD--PCKNEATCLNEI 230
Query: 253 GSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
G + C C Y+ G NC ++DEC PC +C + G Y C C G+ +
Sbjct: 231 GRYTCICPHNYS----GVNCELEIDEC--WSQPC--LNGATCQDALGAYFCDCAPGF--L 280
Query: 312 GRRC-VDRDECKELPYVCAGGECRNFNGGYVCEC 344
G C ++ DEC P + GG C + Y C C
Sbjct: 281 GDHCELNTDECASQPCL-HGGLCVDGENRYSCNC 313
Score = 101 bits (243), Expect = 8e-21
Identities = 105/380 (27%), Positives = 147/380 (38%), Gaps = 57/380 (15%)
Query: 290 NPSCTNTNGGYECSCGAGWKLVGRRCVD-RDECKELPYVCAGGE-CRNFNG--GYVCECP 345
N +C + + +CSC + + C + +D C P C G C N G ++C+CP
Sbjct: 67 NSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNP--CQGSATCVNTPGERSFLCKCP 124
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCE----R 401
G+ K C G CH+ P+ P C C G A GR+CE
Sbjct: 125 PGYSGTICETTIGSCGKNSCQ---HGGICHQD-PIY---PVCICPAGYA-GRFCEIDHDE 176
Query: 402 CPAPDSAEFMRICQGGM---------GRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRC 451
C A + +CQ G+ G DL+ D C C+N G + C
Sbjct: 177 C-ASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTC 235
Query: 452 ECPDGYVLAPDGLSC-VDADECALDPRICGNG-TCSNTRGGYECQCSPGFTQGPDQTCVD 509
CP Y G++C ++ DEC P C NG TC + G Y C C+PGF D ++
Sbjct: 236 ICPHNY----SGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFLG--DHCELN 287
Query: 510 VDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDE-CVQEPRVCPHACENV 568
DECA C + + C C G HC + C +P CE+
Sbjct: 288 TDECASQPCLHGGLCVDGENRYSCNCT---GSGFTGTHCETLMPLCWSKPCHNNATCEDS 344
Query: 569 VGSYICKCPEGYRRTSAPQD----SENACEDINEC-----EEQEDLCSG---GVCINTDG 616
V +Y C C GY D + N C+ EC E+Q +G +
Sbjct: 345 VDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEAS 404
Query: 617 SFLCDCDAGF--EPSEDGTD 634
++C C GF E E G D
Sbjct: 405 GYVCICQPGFTGEAKEMGYD 424
Score = 84.2 bits (199), Expect = 2e-15
Identities = 90/336 (26%), Positives = 129/336 (38%), Gaps = 38/336 (11%)
Query: 204 NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNTVG--SFRCECAP 261
N TC++ C C D + DC ++ + + C NT G SF C+C P
Sbjct: 67 NSTCKDFSKDNDCSCSDTAN-NLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPP 125
Query: 262 GYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRD 319
GY+ G C + C + + C G C C C AG+ GR C +D D
Sbjct: 126 GYS----GTICETTIGSCGK--NSCQHGG--ICHQDPIYPVCICPAGY--AGRFCEIDHD 175
Query: 320 ECKELPYVCAGGE-CRNFNGGYVCECPAGWRFDKTAAVCVDE-RKELCYDEW----EAGR 373
EC P C G C++ GY C C G++ + + VDE + C +E E GR
Sbjct: 176 ECASSP--CQNGAVCQDGIDGYSCFCVPGYQ-GRHCDLEVDECASDPCKNEATCLNEIGR 232
Query: 374 CHRARPLQLARPECCCSEGAAWGRYC---ERCPAPDSAEFMRICQGGMGRPNLTQDLDEC 430
P + C W + C C A F G +G + + DEC
Sbjct: 233 YTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG-DHCELNTDEC 291
Query: 431 RVRPDVCV-GGRCVNTDGSFRCECP-DGYVLAPDGLSCVDADECALDPRICGNGTCSNTR 488
+P C+ GG CV+ + + C C G+ G C N TC ++
Sbjct: 292 ASQP--CLHGGLCVDGENRYSCNCTGSGFT----GTHCETLMPLCWSKPCHNNATCEDSV 345
Query: 489 GGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRC 524
Y C C PG+T Q +D++EC C
Sbjct: 346 DNYTCHCWPGYTGA--QCEIDLNECNSNPCQSNGEC 379
Score = 80.2 bits (189), Expect = 3e-14
Identities = 63/207 (30%), Positives = 80/207 (38%), Gaps = 23/207 (11%)
Query: 68 IDECDIMPQLCK-PGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
+DEC P CK TC + + C C H Y N ++DEC W +P C A C
Sbjct: 212 VDECASDP--CKNEATCLNEIGRYTCICPHNYSGVNCE---LEIDEC-WSQP-CLNGATC 264
Query: 127 VNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR 185
+ GA+ C C PG+ D CE + DEC Q G C + Y C C G
Sbjct: 265 QDALGAYFCDCAPGFLG----DHCELNTDECASQPCLHGGLCVDGENRYSCNCT-GSGFT 319
Query: 186 ENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGP---------NNDCVDVNEC 236
C + +P N TCE+ Y CHC G+ +N C EC
Sbjct: 320 GTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGEC 379
Query: 237 REGGMVCRNGRCRNTVGSFRCECAPGY 263
E + GR SF A GY
Sbjct: 380 VELSSEKQYGRITGLPSSFSYHEASGY 406
Score = 66.9 bits (156), Expect = 3e-10
Identities = 43/120 (35%), Positives = 55/120 (45%), Gaps = 16/120 (13%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D DECA+ P +C G + C C PGY+ G C +VDECA P + C N
Sbjct: 173 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQ--GRHCDLEVDECASDPCKNEATCLNEI 230
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
G Y C+C Y G NC ++DEC C + G+Y C C G+ GD C
Sbjct: 231 GRYTCICPHNY----SGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGF--LGDHC 284
Score = 44.4 bits (100), Expect = 0.002
Identities = 35/113 (30%), Positives = 50/113 (44%), Gaps = 13/113 (11%)
Query: 747 DVDECAAIPGL----C--APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTD 799
++DEC + P L C A G + C C PG+ G+ C + DECA +P LC + +
Sbjct: 249 EIDECWSQPCLNGATCQDALGAYFCDCAPGF--LGDHCELNTDECASQPCLHGGLCVDGE 306
Query: 800 GSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
Y C C TG G +C + C C ++ +Y C C GY
Sbjct: 307 NRYSCNC-TGSGF--TGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY 356
>U77493-1|AAB19224.1| 263|Homo sapiens Notch2 protein.
Length = 263
Score = 114 bits (274), Expect = 1e-24
Identities = 85/271 (31%), Positives = 124/271 (45%), Gaps = 34/271 (12%)
Query: 90 FQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDE 149
+ C C G++ H +++EC+ C CV+ +F C CP G+ + L E
Sbjct: 5 YTCKCQAGFDG---VHCENNINECT--ESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHE 59
Query: 150 CEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCEN 209
++EC + G C + +G+YRC C GYT +N V+ CSR P GTC
Sbjct: 60 ---INECSSHPCLNDGTCVDGLGTYRCSCPLGYT-GKNCQTLVNLCSR-SPCKNKGTCVQ 114
Query: 210 LPGAYLCHCDDGFKAG----PNNDCVDVNECREGGMV---CR-NGRCRNTVGSFRCECAP 261
+ C C G+ PN C D+ R G +V C+ +G C N + C+C
Sbjct: 115 KKASPQCLCPSGWVGAYCDVPNVSC-DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPV 173
Query: 262 GYTLTADGRNCRD-VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRD 319
GYT G C + +DEC +PC +C++ GGY C C G++ G C + D
Sbjct: 174 GYT----GSYCEEQLDEC--ASNPC--QHGATCSDFIGGYRCECVPGYQ--GVNCEYEVD 223
Query: 320 ECKELPYVCA-GGECRNFNGGYVCECPAGWR 349
EC+ P C GG C + + C CP G R
Sbjct: 224 ECQNQP--CQNGGTCIDLVNHFKCSCPPGTR 252
Score = 94.3 bits (224), Expect = 2e-18
Identities = 77/254 (30%), Positives = 109/254 (42%), Gaps = 37/254 (14%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
GTC D F C C G+ T C +++ECS PC CV+ G + C CP
Sbjct: 34 GTCVDGINSFSCLCPVGF----TGSFCLHEINECS--SHPCLNDGTCVDGLGTYRCSCPL 87
Query: 140 GYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYRCECKPG----YTLRENVCRDVDE 194
GY + C+ V+ C + G C S +C C G Y NV D+
Sbjct: 88 GY----TGKNCQTLVNLCSRSPCKNKGTCVQKKASPQCLCPSGWVGAYCDVPNVSCDIAA 143
Query: 195 CSR---PRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCR 249
R +C+ +G C N + C C G+ + +D EC C++G C
Sbjct: 144 SRRGVLVEHLCQHSGVCINAGNTHYCQCPVGYTGSYCEEQLD--ECASN--PCQHGATCS 199
Query: 250 NTVGSFRCECAPGYTLTADGRNCR-DVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW 308
+ +G +RCEC PGY G NC +VDEC PC G +C + ++CSC G
Sbjct: 200 DFIGGYRCECVPGY----QGVNCEYEVDECQN--QPCQNGG--TCIDLVNHFKCSCPPGT 251
Query: 309 KLVGRRCVDR-DEC 321
+ G C + D+C
Sbjct: 252 R--GLLCEENIDDC 263
Score = 94.3 bits (224), Expect = 2e-18
Identities = 72/221 (32%), Positives = 101/221 (45%), Gaps = 27/221 (12%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
I+EC P L GTC D ++C C GY N L V+ CS R PC+ CV
Sbjct: 60 INECSSHPCL-NDGTCVDGLGTYRCSCPLGYTGKNCQTL---VNLCS--RSPCKNKGTCV 113
Query: 128 NLPGAFECRCPPG----YRLTP--SLDECEDVDECGDQRICDH-GDCRNTIGSYRCECKP 180
+ +C CP G Y P S D + +C H G C N ++ C+C
Sbjct: 114 QKKASPQCLCPSGWVGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPV 173
Query: 181 GYTLRENVCRD-VDECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREG 239
GYT + C + +DEC+ P TC + G Y C C G++ G N + +V+EC+
Sbjct: 174 GYT--GSYCEEQLDECA-SNPCQHGATCSDFIGGYRCECVPGYQ-GVNCE-YEVDECQ-- 226
Query: 240 GMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNCRD-VDEC 278
C+N G C + V F+C C PG G C + +D+C
Sbjct: 227 NQPCQNGGTCIDLVNHFKCSCPPG----TRGLLCEENIDDC 263
Score = 89.4 bits (212), Expect = 5e-17
Identities = 69/232 (29%), Positives = 101/232 (43%), Gaps = 40/232 (17%)
Query: 410 FMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVD 468
F +C G +++EC P C+ G CV+ G++RC CP GY G +C
Sbjct: 43 FSCLCPVGFTGSFCLHEINECSSHP--CLNDGTCVDGLGTYRCSCPLGYT----GKNCQT 96
Query: 469 -ADECALDPRICGN-GTCSNTRGGYECQCSPGFTQG----PDQTCVDVDECAEG---RAS 519
+ C+ P C N GTC + +C C G+ P+ +C D+ G
Sbjct: 97 LVNLCSRSP--CKNKGTCVQKKASPQCLCPSGWVGAYCDVPNVSC-DIAASRRGVLVEHL 153
Query: 520 CTFR--CHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPHA--CENVVGSYIC 574
C C N + C CP GY G +C + +DEC P C H C + +G Y C
Sbjct: 154 CQHSGVCINAGNTHYCQCPVGYT----GSYCEEQLDECASNP--CQHGATCSDFIGGYRC 207
Query: 575 KCPEGYRRTSAPQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAG 625
+C GY+ + CE +++EC+ Q +GG CI+ F C C G
Sbjct: 208 ECVPGYQGVN--------CEYEVDECQNQ-PCQNGGTCIDLVNHFKCSCPPG 250
Score = 83.8 bits (198), Expect = 2e-15
Identities = 62/223 (27%), Positives = 95/223 (42%), Gaps = 26/223 (11%)
Query: 414 CQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSCV-DADEC 472
CQ G + +++EC GG CV+ SF C CP G+ G C+ + +EC
Sbjct: 9 CQAGFDGVHCENNINEC-TESSCFNGGTCVDGINSFSCLCPVGFT----GSFCLHEINEC 63
Query: 473 ALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFR 532
+ P + +GTC + G Y C C G+T QT V++ C+ C S +
Sbjct: 64 SSHPCL-NDGTCVDGLGTYRCSCPLGYTGKNCQTLVNL--CSRSPCKNKGTCVQKKASPQ 120
Query: 533 CTCPYGYAVA---ADGVHCRDIDEC---VQEPRVCPHA--CENVVGSYICKCPEGYRRTS 584
C CP G+ A V C DI V +C H+ C N ++ C+CP GY +
Sbjct: 121 CLCPSGWVGAYCDVPNVSC-DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPVGYTGSY 179
Query: 585 APQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
+ + N C+ G C + G + C+C G++
Sbjct: 180 CEEQLDECAS--NPCQH------GATCSDFIGGYRCECVPGYQ 214
Score = 83.4 bits (197), Expect = 3e-15
Identities = 86/317 (27%), Positives = 134/317 (42%), Gaps = 70/317 (22%)
Query: 171 IGSYRCECKPGYTLRENVCRDVDECSRPRPVCRN-GTCENLPGAYLCHCDDGFKAGPNND 229
+ SY C+C+ G+ + +++EC+ C N GTC + ++ C C GF +
Sbjct: 2 VNSYTCKCQAGFD-GVHCENNINECTESS--CFNGGTCVDGINSFSCLCPVGF---TGSF 55
Query: 230 CV-DVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRD-VDECDELPHPCGR 287
C+ ++NEC + +G C + +G++RC C GYT G+NC+ V+ C PC
Sbjct: 56 CLHEINECSSHPCL-NDGTCVDGLGTYRCSCPLGYT----GKNCQTLVNLCSR--SPCKN 108
Query: 288 DGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECK--------ELPYVCA-GGECRNFN 337
G +C +C C +GW VG C V C + ++C G C N
Sbjct: 109 KG--TCVQKKASPQCLCPSGW--VGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAG 164
Query: 338 GGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGR 397
+ C+CP G+ T + C ++ DE + C CS+ G
Sbjct: 165 NTHYCQCPVGY----TGSYCEEQ-----LDECASNPCQHG---------ATCSDFIG-GY 205
Query: 398 YCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDG 456
CE C G N ++DEC+ +P C GG C++ F+C CP G
Sbjct: 206 RCE-------------CVPGYQGVNCEYEVDECQNQP--CQNGGTCIDLVNHFKCSCPPG 250
Query: 457 YVLAPDGLSCVD-ADEC 472
GL C + D+C
Sbjct: 251 ----TRGLLCEENIDDC 263
Score = 76.6 bits (180), Expect = 4e-13
Identities = 84/291 (28%), Positives = 115/291 (39%), Gaps = 52/291 (17%)
Query: 300 YECSCGAGWKLVGRRCVDR-DECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCV 358
Y C C AG+ G C + +EC E GG C + + C CP G+ T + C+
Sbjct: 5 YTCKCQAGFD--GVHCENNINECTESSCF-NGGTCVDGINSFSCLCPVGF----TGSFCL 57
Query: 359 DERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGM 418
E E C L + C +G G Y RC P G
Sbjct: 58 HEINE----------CSSHPCLN----DGTCVDGL--GTY--RCSCP---------LGYT 90
Query: 419 GRPNLTQDLDECRVRPDVCVG-GRCVNTDGSFRCECPDGYVLAPDGLSCVDADECA---- 473
G+ N ++ C P C G CV S +C CP G+V A + V D A
Sbjct: 91 GK-NCQTLVNLCSRSP--CKNKGTCVQKKASPQCLCPSGWVGAYCDVPNVSCDIAASRRG 147
Query: 474 -LDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSF 531
L +C + G C N + CQC G+T + +DECA C + G +
Sbjct: 148 VLVEHLCQHSGVCINAGNTHYCQCPVGYTGSYCEE--QLDECASNPCQHGATCSDFIGGY 205
Query: 532 RCTCPYGYAVAADGVHCR-DIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
RC C GY GV+C ++DEC +P C ++V + C CP G R
Sbjct: 206 RCECVPGY----QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTR 252
Score = 75.8 bits (178), Expect = 6e-13
Identities = 62/219 (28%), Positives = 91/219 (41%), Gaps = 27/219 (12%)
Query: 448 SFRCECPDGYVLAPDGLSCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQT 506
S+ C+C G+ DG+ C + +EC + GTC + + C C GFT
Sbjct: 4 SYTCKCQAGF----DGVHCENNINECT-ESSCFNGGTCVDGINSFSCLCPVGFT---GSF 55
Query: 507 CV-DVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRD-IDECVQEPRVCPHA 564
C+ +++EC+ C + G++RC+CP GY G +C+ ++ C + P
Sbjct: 56 CLHEINECSSHPCLNDGTCVDGLGTYRCSCPLGYT----GKNCQTLVNLCSRSPCKNKGT 111
Query: 565 CENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQ---EDLCS-GGVCINTDGSFLC 620
C S C CP G+ A D N DI E LC GVCIN + C
Sbjct: 112 CVQKKASPQCLCPSGW--VGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYC 169
Query: 621 DCDAGFEPS---EDGTDCID---RRTGTCYRSLVSGRCE 653
C G+ S E +C + TC + RCE
Sbjct: 170 QCPVGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCE 208
Score = 52.8 bits (121), Expect = 5e-06
Identities = 36/107 (33%), Positives = 46/107 (42%), Gaps = 12/107 (11%)
Query: 756 GLC--APGRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G+C A C C GY G C + +DECA P C + G Y C C GY+
Sbjct: 158 GVCINAGNTHYCQCPVGY--TGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQ- 214
Query: 813 DEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC 858
G NC +VDEC+ C + ++CSC G RG C
Sbjct: 215 ---GVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG--TRGLLC 256
Score = 49.2 bits (112), Expect = 6e-05
Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 10/100 (10%)
Query: 756 GLCAPG--RFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 812
G C G F C+C G+ G C +++EC+ P D C + G+Y C C GY
Sbjct: 34 GTCVDGINSFSCLCPVGF--TGSFCLHEINECSSHPCLNDGTCVDGLGTYRCSCPLGY-- 89
Query: 813 DEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGY 851
G NC+ V+ C R + C + S +C C G+
Sbjct: 90 --TGKNCQTLVNLCSRSPCKNKGTCVQKKASPQCLCPSGW 127
Score = 43.6 bits (98), Expect = 0.003
Identities = 30/90 (33%), Positives = 39/90 (43%), Gaps = 14/90 (15%)
Query: 569 VGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFEP 628
V SY CKC G+ D + +INEC E +GG C++ SF C C GF
Sbjct: 2 VNSYTCKCQAGF-------DGVHCENNINECTESSCF-NGGTCVDGINSFSCLCPVGFTG 53
Query: 629 S---EDGTDCIDR---RTGTCYRSLVSGRC 652
S + +C GTC L + RC
Sbjct: 54 SFCLHEINECSSHPCLNDGTCVDGLGTYRC 83
>AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein.
Length = 723
Score = 114 bits (274), Expect = 1e-24
Identities = 95/317 (29%), Positives = 135/317 (42%), Gaps = 37/317 (11%)
Query: 38 CPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHG 97
C P H C +KPGE V + + DEC P C GTC +QC C G
Sbjct: 226 CLPGCDEQH-GFC-DKPGECKCRVGWQGRYCDECIRYPG-CLHGTCQQP---WQCNCQEG 279
Query: 98 YEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNL-PGAFECRCPPGYRLTPSLDECEDVDE 155
+ C +D++ C+ +P C+ A C N G++ C C PGY T + E +DE
Sbjct: 280 WG----GLFCNQDLNYCTHHKP-CKNGATCTNTGQGSYTCSCRPGY--TGATCEL-GIDE 331
Query: 156 CGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLP-GAY 214
C + G C + SY C C PG+ +C P G C + P G Y
Sbjct: 332 CDPSPCKNGGSCTDLENSYSCTCPPGF--YGKICELSAMTCADGPCFNGGRCSDSPDGGY 389
Query: 215 LCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCR 273
C C G+ +G N + ++ C C NG +C + ++ C C G++ GR+C
Sbjct: 390 SCRCPVGY-SGFNCE-KKIDYC--SSSPCSNGAKCVDLGDAYLCRCQAGFS----GRHCD 441
Query: 274 D-VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGG 331
D VD+C PC G +C + + C+C G+ GR C C+ P G
Sbjct: 442 DNVDDC--ASSPCANGG--TCRDGVNDFSCTCPPGY--TGRNCSAPVSRCEHAP-CHNGA 494
Query: 332 ECRNFNGGYVCECPAGW 348
C YVCEC G+
Sbjct: 495 TCHERGHRYVCECARGY 511
Score = 97.1 bits (231), Expect = 2e-19
Identities = 88/330 (26%), Positives = 127/330 (38%), Gaps = 64/330 (19%)
Query: 301 ECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
EC C GW+ GR C DEC P C G C+ + C C GW C
Sbjct: 242 ECKCRVGWQ--GRYC---DECIRYPG-CLHGTCQQ---PWQCNCQEGWG----GLFC--- 285
Query: 361 RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGR 420
++L Y C +P C GA C + C+ G
Sbjct: 286 NQDLNY-------CTHHKP---------CKNGAT-------CTNTGQGSYTCSCRPGYTG 322
Query: 421 PNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRI 478
+DEC P C GG C + + S+ C CP G+ G C + A CA P
Sbjct: 323 ATCELGIDECD--PSPCKNGGSCTDLENSYSCTCPPGFY----GKICELSAMTCADGPCF 376
Query: 479 CGNGTCSNT-RGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPY 537
G G CS++ GGY C+C G++ + +D C+ S +C + ++ C C
Sbjct: 377 NG-GRCSDSPDGGYSCRCPVGYSGFNCEK--KIDYCSSSPCSNGAKCVDLGDAYLCRCQA 433
Query: 538 GYAVAADGVHCRD-IDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDI 596
G++ G HC D +D+C P C + V + C CP GY N +
Sbjct: 434 GFS----GRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGY-------TGRNCSAPV 482
Query: 597 NECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
+ C E +G C ++C+C G+
Sbjct: 483 SRC-EHAPCHNGATCHERGHRYVCECARGY 511
Score = 92.3 bits (219), Expect = 7e-18
Identities = 55/150 (36%), Positives = 71/150 (47%), Gaps = 16/150 (10%)
Query: 81 GTCHDTPTG-FQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
G C D+P G + C C GY N + +D CS PC A+CV+L A+ CRC
Sbjct: 379 GRCSDSPDGGYSCRCPVGYSGFNCE---KKIDYCS--SSPCSNGAKCVDLGDAYLCRCQA 433
Query: 140 GYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRP 198
G+ S C+D VD+C + G CR+ + + C C PGYT R N V C
Sbjct: 434 GF----SGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGR-NCSAPVSRCE-- 486
Query: 199 RPVCRNG-TCENLPGAYLCHCDDGFKAGPN 227
C NG TC Y+C C G+ GPN
Sbjct: 487 HAPCHNGATCHERGHRYVCECARGY-GGPN 515
Score = 44.0 bits (99), Expect = 0.002
Identities = 35/108 (32%), Positives = 44/108 (40%), Gaps = 18/108 (16%)
Query: 761 GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGA 817
G + C C PGY G C +DEC P PC C + + SY C C G+ G
Sbjct: 310 GSYTCSCRPGY--TGATCELGIDECD--PSPCKNGGSCTDLENSYSCTCPPGFY----GK 361
Query: 818 NCR-DVDECERDTHTCQQICSNT-EGSYECSCEDGY-----EKRGDAC 858
C C CS++ +G Y C C GY EK+ D C
Sbjct: 362 ICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYC 409
Score = 42.7 bits (96), Expect = 0.005
Identities = 27/96 (28%), Positives = 40/96 (41%), Gaps = 8/96 (8%)
Query: 761 GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G + C C GY +G C +D C+ P C + +Y C C+ G+ G +C
Sbjct: 387 GGYSCRCPVGY--SGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFS----GRHC 440
Query: 820 RD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
D VD+C C + + C+C GY R
Sbjct: 441 DDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGR 476
Score = 42.3 bits (95), Expect = 0.007
Identities = 28/91 (30%), Positives = 34/91 (37%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 820
+ C C G+ +G C D VD+CA P C + + C C GY G NC
Sbjct: 427 YLCRCQAGF--SGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGY----TGRNCSA 480
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
V CE C Y C C GY
Sbjct: 481 PVSRCEHAPCHNGATCHERGHRYVCECARGY 511
Score = 39.5 bits (88), Expect = 0.050
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 22/107 (20%)
Query: 751 CAAIPGLC-APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNT-DGSYDCLCRT 808
C G C PG C C G++ G C DEC +R P C H T + C C+
Sbjct: 230 CDEQHGFCDKPGE--CKCRVGWQ--GRYC---DEC-IRYPGC---LHGTCQQPWQCNCQE 278
Query: 809 GYELDEDGANC-RDVDECERDTHTCQQ--ICSNT-EGSYECSCEDGY 851
G+ G C +D++ C C+ C+NT +GSY CSC GY
Sbjct: 279 GW----GGLFCNQDLNYCTHHK-PCKNGATCTNTGQGSYTCSCRPGY 320
Score = 33.9 bits (74), Expect = 2.5
Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 16/86 (18%)
Query: 766 VCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC 825
VC PG++ G C + + P CD+ D +C CR G++ G C DEC
Sbjct: 211 VCNPGWK--GPYCTE----PICLPGCDEQHGFCDKPGECKCRVGWQ----GRYC---DEC 257
Query: 826 ERDTHTCQQICSNTEGSYECSCEDGY 851
R C + ++C+C++G+
Sbjct: 258 IRYPGCLHGTC---QQPWQCNCQEGW 280
>AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophila)
protein.
Length = 723
Score = 114 bits (274), Expect = 1e-24
Identities = 95/317 (29%), Positives = 135/317 (42%), Gaps = 37/317 (11%)
Query: 38 CPPRGSPAHTALCGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHG 97
C P H C +KPGE V + + DEC P C GTC +QC C G
Sbjct: 226 CLPGCDEQH-GFC-DKPGECKCRVGWQGRYCDECIRYPG-CLHGTCQQP---WQCNCQEG 279
Query: 98 YEHDNTSHLC-RDVDECSWGRPPCRGMAQCVNL-PGAFECRCPPGYRLTPSLDECEDVDE 155
+ C +D++ C+ +P C+ A C N G++ C C PGY T + E +DE
Sbjct: 280 WG----GLFCNQDLNYCTHHKP-CKNGATCTNTGQGSYTCSCRPGY--TGATCEL-GIDE 331
Query: 156 CGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLP-GAY 214
C + G C + SY C C PG+ +C P G C + P G Y
Sbjct: 332 CDPSPCKNGGSCTDLENSYSCTCPPGF--YGKICELSAMTCADGPCFNGGRCSDSPDGGY 389
Query: 215 LCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADGRNCR 273
C C G+ +G N + ++ C C NG +C + ++ C C G++ GR+C
Sbjct: 390 SCRCPVGY-SGFNCE-KKIDYC--SSSPCSNGAKCVDLGDAYLCRCQAGFS----GRHCD 441
Query: 274 D-VDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAGG 331
D VD+C PC G +C + + C+C G+ GR C C+ P G
Sbjct: 442 DNVDDC--ASSPCANGG--TCRDGVNDFSCTCPPGY--TGRNCSAPVSRCEHAP-CHNGA 494
Query: 332 ECRNFNGGYVCECPAGW 348
C YVCEC G+
Sbjct: 495 TCHERGHRYVCECARGY 511
Score = 97.1 bits (231), Expect = 2e-19
Identities = 88/330 (26%), Positives = 127/330 (38%), Gaps = 64/330 (19%)
Query: 301 ECSCGAGWKLVGRRCVDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDE 360
EC C GW+ GR C DEC P C G C+ + C C GW C
Sbjct: 242 ECKCRVGWQ--GRYC---DECIRYPG-CLHGTCQQ---PWQCNCQEGWG----GLFC--- 285
Query: 361 RKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGR 420
++L Y C +P C GA C + C+ G
Sbjct: 286 NQDLNY-------CTHHKP---------CKNGAT-------CTNTGQGSYTCSCRPGYTG 322
Query: 421 PNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSC-VDADECALDPRI 478
+DEC P C GG C + + S+ C CP G+ G C + A CA P
Sbjct: 323 ATCELGIDECD--PSPCKNGGSCTDLENSYSCTCPPGFY----GKICELSAMTCADGPCF 376
Query: 479 CGNGTCSNT-RGGYECQCSPGFTQGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPY 537
G G CS++ GGY C+C G++ + +D C+ S +C + ++ C C
Sbjct: 377 NG-GRCSDSPDGGYSCRCPVGYSGFNCEK--KIDYCSSSPCSNGAKCVDLGDAYLCRCQA 433
Query: 538 GYAVAADGVHCRD-IDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDI 596
G++ G HC D +D+C P C + V + C CP GY N +
Sbjct: 434 GFS----GRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGY-------TGRNCSAPV 482
Query: 597 NECEEQEDLCSGGVCINTDGSFLCDCDAGF 626
+ C E +G C ++C+C G+
Sbjct: 483 SRC-EHAPCHNGATCHERGHRYVCECARGY 511
Score = 92.3 bits (219), Expect = 7e-18
Identities = 55/150 (36%), Positives = 71/150 (47%), Gaps = 16/150 (10%)
Query: 81 GTCHDTPTG-FQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
G C D+P G + C C GY N + +D CS PC A+CV+L A+ CRC
Sbjct: 379 GRCSDSPDGGYSCRCPVGYSGFNCE---KKIDYCS--SSPCSNGAKCVDLGDAYLCRCQA 433
Query: 140 GYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRP 198
G+ S C+D VD+C + G CR+ + + C C PGYT R N V C
Sbjct: 434 GF----SGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGR-NCSAPVSRCE-- 486
Query: 199 RPVCRNG-TCENLPGAYLCHCDDGFKAGPN 227
C NG TC Y+C C G+ GPN
Sbjct: 487 HAPCHNGATCHERGHRYVCECARGY-GGPN 515
Score = 44.0 bits (99), Expect = 0.002
Identities = 35/108 (32%), Positives = 44/108 (40%), Gaps = 18/108 (16%)
Query: 761 GRFRCVCGPGYRPAGEVCA-DVDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGA 817
G + C C PGY G C +DEC P PC C + + SY C C G+ G
Sbjct: 310 GSYTCSCRPGY--TGATCELGIDECD--PSPCKNGGSCTDLENSYSCTCPPGFY----GK 361
Query: 818 NCR-DVDECERDTHTCQQICSNT-EGSYECSCEDGY-----EKRGDAC 858
C C CS++ +G Y C C GY EK+ D C
Sbjct: 362 ICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYC 409
Score = 42.7 bits (96), Expect = 0.005
Identities = 27/96 (28%), Positives = 40/96 (41%), Gaps = 8/96 (8%)
Query: 761 GRFRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
G + C C GY +G C +D C+ P C + +Y C C+ G+ G +C
Sbjct: 387 GGYSCRCPVGY--SGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFS----GRHC 440
Query: 820 RD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
D VD+C C + + C+C GY R
Sbjct: 441 DDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGR 476
Score = 42.3 bits (95), Expect = 0.007
Identities = 28/91 (30%), Positives = 34/91 (37%), Gaps = 8/91 (8%)
Query: 763 FRCVCGPGYRPAGEVCAD-VDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 820
+ C C G+ +G C D VD+CA P C + + C C GY G NC
Sbjct: 427 YLCRCQAGF--SGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGY----TGRNCSA 480
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
V CE C Y C C GY
Sbjct: 481 PVSRCEHAPCHNGATCHERGHRYVCECARGY 511
Score = 39.5 bits (88), Expect = 0.050
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 22/107 (20%)
Query: 751 CAAIPGLC-APGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNT-DGSYDCLCRT 808
C G C PG C C G++ G C DEC +R P C H T + C C+
Sbjct: 230 CDEQHGFCDKPGE--CKCRVGWQ--GRYC---DEC-IRYPGC---LHGTCQQPWQCNCQE 278
Query: 809 GYELDEDGANC-RDVDECERDTHTCQQ--ICSNT-EGSYECSCEDGY 851
G+ G C +D++ C C+ C+NT +GSY CSC GY
Sbjct: 279 GW----GGLFCNQDLNYCTHHK-PCKNGATCTNTGQGSYTCSCRPGY 320
Score = 33.9 bits (74), Expect = 2.5
Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 16/86 (18%)
Query: 766 VCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC 825
VC PG++ G C + + P CD+ D +C CR G++ G C DEC
Sbjct: 211 VCNPGWK--GPYCTE----PICLPGCDEQHGFCDKPGECKCRVGWQ----GRYC---DEC 257
Query: 826 ERDTHTCQQICSNTEGSYECSCEDGY 851
R C + ++C+C++G+
Sbjct: 258 IRYPGCLHGTC---QQPWQCNCQEGW 280
>M16552-1|AAB59508.1| 575|Homo sapiens THBD protein.
Length = 575
Score = 111 bits (267), Expect = 1e-23
Identities = 80/208 (38%), Positives = 99/208 (47%), Gaps = 24/208 (11%)
Query: 435 DVCVGGRCVNTD--GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYE 492
D+C N D GS+ C C GY LA D C D D+C L+P C C NT+GG+E
Sbjct: 290 DLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFE 348
Query: 493 CQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHN-TAGSFRCTCPYGYAVAADGVH-CR 549
C C P + D CV+ VD C RA+C ++C S+ C C G+A H C+
Sbjct: 349 CHCYPNYDL-VDGECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQ 405
Query: 550 DIDECVQEPRVCPHACE-NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSG 608
C Q CP C+ N S C+CPEGY D C DI+EC E CS
Sbjct: 406 MF--CNQ--TACPADCDPNTQAS--CECPEGY-----ILDDGFICTDIDEC-ENGGFCS- 452
Query: 609 GVCINTDGSFLCDCDAGFEPSED-GTDC 635
GVC N G+F C C + GTDC
Sbjct: 453 GVCHNLPGTFECICGPDSALARHIGTDC 480
Score = 99.5 bits (237), Expect = 4e-20
Identities = 95/310 (30%), Positives = 121/310 (39%), Gaps = 41/310 (13%)
Query: 30 AWGAPCEACPPRGSPAHTAL-----CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCH 84
A GA +A P S A L C PG E +C + C+ C+
Sbjct: 199 ARGADFQALPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CN 257
Query: 85 DTPTGFQCGCDHG--YEHDNTSHLCRDVDECSWGRPPCRGMAQCV---NLPGAFECRCPP 139
P +C C G + D S C+ C CV + PG++ C C
Sbjct: 258 AIPGAPRCQCPAGAALQADGRSCTASATQSCN---DLCEHF--CVPNPDQPGSYSCMCET 312
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVC-RDVDECSRP 198
GYRL CEDVD+C + C NT G + C C P Y L + C VD C R
Sbjct: 313 GYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRA 372
Query: 199 RPVCRNGTCENL-PGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC-----RNTV 252
C C+ L +YLC C +GF P+ + + C+ M C C NT
Sbjct: 373 N--CEY-QCQPLNQTSYLCVCAEGFAPIPH----EPHRCQ---MFCNQTACPADCDPNTQ 422
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
S CEC GY L DG C D+DEC+ G + C N G +EC CG L
Sbjct: 423 AS--CECPEGYILD-DGFICTDIDECEN-----GGFCSGVCHNLPGTFECICGPDSALAR 474
Query: 313 RRCVDRDECK 322
D D K
Sbjct: 475 HIGTDCDSGK 484
Score = 80.6 bits (190), Expect = 2e-14
Identities = 41/108 (37%), Positives = 55/108 (50%), Gaps = 6/108 (5%)
Query: 747 DVDECAAIPGLCAPGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNTDGSYDC 804
D+ E +P PG + C+C GYR A + C DVD+C + P PC Q C NT G ++C
Sbjct: 290 DLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFEC 349
Query: 805 LCRTGYELDEDGANCRDVDECERDTHTCQQICSN-TEGSYECSCEDGY 851
C Y+L DG VD C R C+ C + SY C C +G+
Sbjct: 350 HCYPNYDL-VDGECVEPVDPCFR--ANCEYQCQPLNQTSYLCVCAEGF 394
Score = 78.2 bits (184), Expect = 1e-13
Identities = 50/159 (31%), Positives = 68/159 (42%), Gaps = 12/159 (7%)
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNT-- 251
+CS C + C +PGA C C G + + + +C + N
Sbjct: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ 302
Query: 252 VGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
GS+ C C GY L AD C DVD+C P PC + C NT GG+EC C + LV
Sbjct: 303 PGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ----RCVNTQGGFECHCYPNYDLV 358
Query: 312 GRRCVDR-DECKELPYVCAGGECRNFN-GGYVCECPAGW 348
CV+ D C C +C+ N Y+C C G+
Sbjct: 359 DGECVEPVDPCFRAN--CE-YQCQPLNQTSYLCVCAEGF 394
Score = 77.8 bits (183), Expect = 2e-13
Identities = 72/246 (29%), Positives = 89/246 (36%), Gaps = 37/246 (15%)
Query: 333 CRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEG 392
C G C+CPAG C + C D E P Q C C G
Sbjct: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCE--HFCVPNPDQPGSYSCMCETG 313
Query: 393 AAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCE 452
RC +D+D+C + P C RCVNT G F C
Sbjct: 314 YRLAADQHRC----------------------EDVDDCILEPSPC-PQRCVNTQGGFECH 350
Query: 453 CPDGYVLAPDGLSCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVD 511
C Y L DG CV+ D C C + Y C C+ GF P +
Sbjct: 351 CYPNYDLV-DG-ECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQM 406
Query: 512 ECAEGRASCTFRCH-NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG 570
C + +C C NT S C CP GY + DG C DIDEC + C C N+ G
Sbjct: 407 FC--NQTACPADCDPNTQAS--CECPEGY-ILDDGFICTDIDEC-ENGGFCSGVCHNLPG 460
Query: 571 SYICKC 576
++ C C
Sbjct: 461 TFECIC 466
Score = 77.4 bits (182), Expect = 2e-13
Identities = 45/116 (38%), Positives = 54/116 (46%), Gaps = 15/116 (12%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCH-----NTD--GSYD 803
C AIPG AP R +C G + G C A C+ LC N D GSY
Sbjct: 256 CNAIPG--AP-RCQCPAGAALQADGRSCT-----ASATQSCNDLCEHFCVPNPDQPGSYS 307
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 859
C+C TGY L D C DVD+C + C Q C NT+G +EC C Y+ CV
Sbjct: 308 CMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECV 363
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/181 (28%), Positives = 67/181 (37%), Gaps = 11/181 (6%)
Query: 451 CECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDV 510
C P G V A +C+++ C + C+ G CQC G D
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTA 282
Query: 511 DECAEGRASCTFRC---HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN 567
C C + GS+ C C GY +AAD C D+D+C+ EP CP C N
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVN 342
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
G + C C Y D E E ++ C C S+LC C GF
Sbjct: 343 TQGGFECHCYPNYDLV----DGE-CVEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFA 395
Query: 628 P 628
P
Sbjct: 396 P 396
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/88 (37%), Positives = 39/88 (44%), Gaps = 10/88 (11%)
Query: 763 FRCVCGPGYRPAGEV---CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
+ CVC G+ P C P CD NT S C C GY LD DG C
Sbjct: 386 YLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDP---NTQAS--CECPEGYILD-DGFIC 439
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSC 847
D+DECE C +C N G++EC C
Sbjct: 440 TDIDECENGGF-CSGVCHNLPGTFECIC 466
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 4/77 (5%)
Query: 783 ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQIC---SNT 839
+C+V C+ C+ G+ C C G L DG +C + C+ C +
Sbjct: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC-TASATQSCNDLCEHFCVPNPDQ 302
Query: 840 EGSYECSCEDGYEKRGD 856
GSY C CE GY D
Sbjct: 303 PGSYSCMCETGYRLAAD 319
Score = 45.2 bits (102), Expect = 0.001
Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 753 AIPGLCAPG-RFRCVCGPGY-RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLC 806
A P C P + C C GY G +C D+DEC C +CHN G+++C+C
Sbjct: 412 ACPADCDPNTQASCECPEGYILDDGFICTDIDECE-NGGFCSGVCHNLPGTFECIC 466
Score = 37.5 bits (83), Expect = 0.20
Identities = 35/104 (33%), Positives = 41/104 (39%), Gaps = 15/104 (14%)
Query: 18 QTKYLCCCSVG--------HAWGAPCE--ACPPRGSPAHTALCGEKPGEYINPVTNETKP 67
QT YLC C+ G H C ACP P A C E P YI
Sbjct: 383 QTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASC-ECPEGYILDDGFICTD 441
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVD 111
IDEC+ C G CH+ P F+C C G + H+ D D
Sbjct: 442 IDECE-NGGFCS-GVCHNLPGTFECIC--GPDSALARHIGTDCD 481
Score = 32.7 bits (71), Expect = 5.7
Identities = 16/44 (36%), Positives = 21/44 (47%), Gaps = 5/44 (11%)
Query: 744 VFADVDEC---AAIPGLC--APGRFRCVCGPGYRPAGEVCADVD 782
+ D+DEC G+C PG F C+CGP A + D D
Sbjct: 438 ICTDIDECENGGFCSGVCHNLPGTFECICGPDSALARHIGTDCD 481
>J02973-1|AAA61175.1| 575|Homo sapiens THBD protein.
Length = 575
Score = 111 bits (267), Expect = 1e-23
Identities = 80/208 (38%), Positives = 99/208 (47%), Gaps = 24/208 (11%)
Query: 435 DVCVGGRCVNTD--GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYE 492
D+C N D GS+ C C GY LA D C D D+C L+P C C NT+GG+E
Sbjct: 290 DLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFE 348
Query: 493 CQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHN-TAGSFRCTCPYGYAVAADGVH-CR 549
C C P + D CV+ VD C RA+C ++C S+ C C G+A H C+
Sbjct: 349 CHCYPNYDL-VDGECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQ 405
Query: 550 DIDECVQEPRVCPHACE-NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSG 608
C Q CP C+ N S C+CPEGY D C DI+EC E CS
Sbjct: 406 MF--CNQ--TACPADCDPNTQAS--CECPEGY-----ILDDGFICTDIDEC-ENGGFCS- 452
Query: 609 GVCINTDGSFLCDCDAGFEPSED-GTDC 635
GVC N G+F C C + GTDC
Sbjct: 453 GVCHNLPGTFECICGPDSALARHIGTDC 480
Score = 99.5 bits (237), Expect = 4e-20
Identities = 95/310 (30%), Positives = 121/310 (39%), Gaps = 41/310 (13%)
Query: 30 AWGAPCEACPPRGSPAHTAL-----CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCH 84
A GA +A P S A L C PG E +C + C+ C+
Sbjct: 199 ARGADFQALPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CN 257
Query: 85 DTPTGFQCGCDHG--YEHDNTSHLCRDVDECSWGRPPCRGMAQCV---NLPGAFECRCPP 139
P +C C G + D S C+ C CV + PG++ C C
Sbjct: 258 AIPGAPRCQCPAGAALQADGRSCTASATQSCN---DLCEHF--CVPNPDQPGSYSCMCET 312
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVC-RDVDECSRP 198
GYRL CEDVD+C + C NT G + C C P Y L + C VD C R
Sbjct: 313 GYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRA 372
Query: 199 RPVCRNGTCENL-PGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC-----RNTV 252
C C+ L +YLC C +GF P+ + + C+ M C C NT
Sbjct: 373 N--CEY-QCQPLNQTSYLCVCAEGFAPIPH----EPHRCQ---MFCNQTACPADCDPNTQ 422
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
S CEC GY L DG C D+DEC+ G + C N G +EC CG L
Sbjct: 423 AS--CECPEGYILD-DGFICTDIDECEN-----GGFCSGVCHNLPGTFECICGPDSALAR 474
Query: 313 RRCVDRDECK 322
D D K
Sbjct: 475 HIGTDCDSGK 484
Score = 80.6 bits (190), Expect = 2e-14
Identities = 41/108 (37%), Positives = 55/108 (50%), Gaps = 6/108 (5%)
Query: 747 DVDECAAIPGLCAPGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNTDGSYDC 804
D+ E +P PG + C+C GYR A + C DVD+C + P PC Q C NT G ++C
Sbjct: 290 DLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFEC 349
Query: 805 LCRTGYELDEDGANCRDVDECERDTHTCQQICSN-TEGSYECSCEDGY 851
C Y+L DG VD C R C+ C + SY C C +G+
Sbjct: 350 HCYPNYDL-VDGECVEPVDPCFR--ANCEYQCQPLNQTSYLCVCAEGF 394
Score = 78.2 bits (184), Expect = 1e-13
Identities = 50/159 (31%), Positives = 68/159 (42%), Gaps = 12/159 (7%)
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNT-- 251
+CS C + C +PGA C C G + + + +C + N
Sbjct: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ 302
Query: 252 VGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
GS+ C C GY L AD C DVD+C P PC + C NT GG+EC C + LV
Sbjct: 303 PGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ----RCVNTQGGFECHCYPNYDLV 358
Query: 312 GRRCVDR-DECKELPYVCAGGECRNFN-GGYVCECPAGW 348
CV+ D C C +C+ N Y+C C G+
Sbjct: 359 DGECVEPVDPCFRAN--CE-YQCQPLNQTSYLCVCAEGF 394
Score = 77.8 bits (183), Expect = 2e-13
Identities = 72/246 (29%), Positives = 89/246 (36%), Gaps = 37/246 (15%)
Query: 333 CRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEG 392
C G C+CPAG C + C D E P Q C C G
Sbjct: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCE--HFCVPNPDQPGSYSCMCETG 313
Query: 393 AAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCE 452
RC +D+D+C + P C RCVNT G F C
Sbjct: 314 YRLAADQHRC----------------------EDVDDCILEPSPC-PQRCVNTQGGFECH 350
Query: 453 CPDGYVLAPDGLSCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVD 511
C Y L DG CV+ D C C + Y C C+ GF P +
Sbjct: 351 CYPNYDLV-DG-ECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQM 406
Query: 512 ECAEGRASCTFRCH-NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG 570
C + +C C NT S C CP GY + DG C DIDEC + C C N+ G
Sbjct: 407 FC--NQTACPADCDPNTQAS--CECPEGY-ILDDGFICTDIDEC-ENGGFCSGVCHNLPG 460
Query: 571 SYICKC 576
++ C C
Sbjct: 461 TFECIC 466
Score = 77.4 bits (182), Expect = 2e-13
Identities = 45/116 (38%), Positives = 54/116 (46%), Gaps = 15/116 (12%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCH-----NTD--GSYD 803
C AIPG AP R +C G + G C A C+ LC N D GSY
Sbjct: 256 CNAIPG--AP-RCQCPAGAALQADGRSCT-----ASATQSCNDLCEHFCVPNPDQPGSYS 307
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 859
C+C TGY L D C DVD+C + C Q C NT+G +EC C Y+ CV
Sbjct: 308 CMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECV 363
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/181 (28%), Positives = 67/181 (37%), Gaps = 11/181 (6%)
Query: 451 CECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDV 510
C P G V A +C+++ C + C+ G CQC G D
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTA 282
Query: 511 DECAEGRASCTFRC---HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN 567
C C + GS+ C C GY +AAD C D+D+C+ EP CP C N
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVN 342
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
G + C C Y D E E ++ C C S+LC C GF
Sbjct: 343 TQGGFECHCYPNYDLV----DGE-CVEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFA 395
Query: 628 P 628
P
Sbjct: 396 P 396
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/88 (37%), Positives = 39/88 (44%), Gaps = 10/88 (11%)
Query: 763 FRCVCGPGYRPAGEV---CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
+ CVC G+ P C P CD NT S C C GY LD DG C
Sbjct: 386 YLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDP---NTQAS--CECPEGYILD-DGFIC 439
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSC 847
D+DECE C +C N G++EC C
Sbjct: 440 TDIDECENGGF-CSGVCHNLPGTFECIC 466
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 4/77 (5%)
Query: 783 ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQIC---SNT 839
+C+V C+ C+ G+ C C G L DG +C + C+ C +
Sbjct: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC-TASATQSCNDLCEHFCVPNPDQ 302
Query: 840 EGSYECSCEDGYEKRGD 856
GSY C CE GY D
Sbjct: 303 PGSYSCMCETGYRLAAD 319
Score = 45.2 bits (102), Expect = 0.001
Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 753 AIPGLCAPG-RFRCVCGPGY-RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLC 806
A P C P + C C GY G +C D+DEC C +CHN G+++C+C
Sbjct: 412 ACPADCDPNTQASCECPEGYILDDGFICTDIDECE-NGGFCSGVCHNLPGTFECIC 466
Score = 37.5 bits (83), Expect = 0.20
Identities = 35/104 (33%), Positives = 41/104 (39%), Gaps = 15/104 (14%)
Query: 18 QTKYLCCCSVG--------HAWGAPCE--ACPPRGSPAHTALCGEKPGEYINPVTNETKP 67
QT YLC C+ G H C ACP P A C E P YI
Sbjct: 383 QTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASC-ECPEGYILDDGFICTD 441
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVD 111
IDEC+ C G CH+ P F+C C G + H+ D D
Sbjct: 442 IDECE-NGGFCS-GVCHNLPGTFECIC--GPDSALARHIGTDCD 481
Score = 32.7 bits (71), Expect = 5.7
Identities = 16/44 (36%), Positives = 21/44 (47%), Gaps = 5/44 (11%)
Query: 744 VFADVDEC---AAIPGLC--APGRFRCVCGPGYRPAGEVCADVD 782
+ D+DEC G+C PG F C+CGP A + D D
Sbjct: 438 ICTDIDECENGGFCSGVCHNLPGTFECICGPDSALARHIGTDCD 481
>BC053357-1|AAH53357.1| 575|Homo sapiens thrombomodulin protein.
Length = 575
Score = 111 bits (267), Expect = 1e-23
Identities = 80/208 (38%), Positives = 99/208 (47%), Gaps = 24/208 (11%)
Query: 435 DVCVGGRCVNTD--GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYE 492
D+C N D GS+ C C GY LA D C D D+C L+P C C NT+GG+E
Sbjct: 290 DLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFE 348
Query: 493 CQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHN-TAGSFRCTCPYGYAVAADGVH-CR 549
C C P + D CV+ VD C RA+C ++C S+ C C G+A H C+
Sbjct: 349 CHCYPNYDL-VDGECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQ 405
Query: 550 DIDECVQEPRVCPHACE-NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSG 608
C Q CP C+ N S C+CPEGY D C DI+EC E CS
Sbjct: 406 MF--CNQ--TACPADCDPNTQAS--CECPEGY-----ILDDGFICTDIDEC-ENGGFCS- 452
Query: 609 GVCINTDGSFLCDCDAGFEPSED-GTDC 635
GVC N G+F C C + GTDC
Sbjct: 453 GVCHNLPGTFECICGPDSALARHIGTDC 480
Score = 99.5 bits (237), Expect = 4e-20
Identities = 95/310 (30%), Positives = 121/310 (39%), Gaps = 41/310 (13%)
Query: 30 AWGAPCEACPPRGSPAHTAL-----CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCH 84
A GA +A P S A L C PG E +C + C+ C+
Sbjct: 199 ARGADFQALPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CN 257
Query: 85 DTPTGFQCGCDHG--YEHDNTSHLCRDVDECSWGRPPCRGMAQCV---NLPGAFECRCPP 139
P +C C G + D S C+ C CV + PG++ C C
Sbjct: 258 AIPGAPRCQCPAGAALQADGRSCTASATQSCN---DLCEHF--CVPNPDQPGSYSCMCET 312
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVC-RDVDECSRP 198
GYRL CEDVD+C + C NT G + C C P Y L + C VD C R
Sbjct: 313 GYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRA 372
Query: 199 RPVCRNGTCENL-PGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC-----RNTV 252
C C+ L +YLC C +GF P+ + + C+ M C C NT
Sbjct: 373 N--CEY-QCQPLNQTSYLCVCAEGFAPIPH----EPHRCQ---MFCNQTACPADCDPNTQ 422
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
S CEC GY L DG C D+DEC+ G + C N G +EC CG L
Sbjct: 423 AS--CECPEGYILD-DGFICTDIDECEN-----GGFCSGVCHNLPGTFECICGPDSALAR 474
Query: 313 RRCVDRDECK 322
D D K
Sbjct: 475 HIGTDCDSGK 484
Score = 80.6 bits (190), Expect = 2e-14
Identities = 41/108 (37%), Positives = 55/108 (50%), Gaps = 6/108 (5%)
Query: 747 DVDECAAIPGLCAPGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNTDGSYDC 804
D+ E +P PG + C+C GYR A + C DVD+C + P PC Q C NT G ++C
Sbjct: 290 DLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFEC 349
Query: 805 LCRTGYELDEDGANCRDVDECERDTHTCQQICSN-TEGSYECSCEDGY 851
C Y+L DG VD C R C+ C + SY C C +G+
Sbjct: 350 HCYPNYDL-VDGECVEPVDPCFR--ANCEYQCQPLNQTSYLCVCAEGF 394
Score = 78.2 bits (184), Expect = 1e-13
Identities = 50/159 (31%), Positives = 68/159 (42%), Gaps = 12/159 (7%)
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNT-- 251
+CS C + C +PGA C C G + + + +C + N
Sbjct: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ 302
Query: 252 VGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
GS+ C C GY L AD C DVD+C P PC + C NT GG+EC C + LV
Sbjct: 303 PGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ----RCVNTQGGFECHCYPNYDLV 358
Query: 312 GRRCVDR-DECKELPYVCAGGECRNFN-GGYVCECPAGW 348
CV+ D C C +C+ N Y+C C G+
Sbjct: 359 DGECVEPVDPCFRAN--CE-YQCQPLNQTSYLCVCAEGF 394
Score = 77.8 bits (183), Expect = 2e-13
Identities = 72/246 (29%), Positives = 89/246 (36%), Gaps = 37/246 (15%)
Query: 333 CRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEG 392
C G C+CPAG C + C D E P Q C C G
Sbjct: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCE--HFCVPNPDQPGSYSCMCETG 313
Query: 393 AAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCE 452
RC +D+D+C + P C RCVNT G F C
Sbjct: 314 YRLAADQHRC----------------------EDVDDCILEPSPC-PQRCVNTQGGFECH 350
Query: 453 CPDGYVLAPDGLSCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVD 511
C Y L DG CV+ D C C + Y C C+ GF P +
Sbjct: 351 CYPNYDLV-DG-ECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQM 406
Query: 512 ECAEGRASCTFRCH-NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG 570
C + +C C NT S C CP GY + DG C DIDEC + C C N+ G
Sbjct: 407 FC--NQTACPADCDPNTQAS--CECPEGY-ILDDGFICTDIDEC-ENGGFCSGVCHNLPG 460
Query: 571 SYICKC 576
++ C C
Sbjct: 461 TFECIC 466
Score = 77.4 bits (182), Expect = 2e-13
Identities = 45/116 (38%), Positives = 54/116 (46%), Gaps = 15/116 (12%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCH-----NTD--GSYD 803
C AIPG AP R +C G + G C A C+ LC N D GSY
Sbjct: 256 CNAIPG--AP-RCQCPAGAALQADGRSCT-----ASATQSCNDLCEHFCVPNPDQPGSYS 307
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 859
C+C TGY L D C DVD+C + C Q C NT+G +EC C Y+ CV
Sbjct: 308 CMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECV 363
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/181 (28%), Positives = 67/181 (37%), Gaps = 11/181 (6%)
Query: 451 CECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDV 510
C P G V A +C+++ C + C+ G CQC G D
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTA 282
Query: 511 DECAEGRASCTFRC---HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN 567
C C + GS+ C C GY +AAD C D+D+C+ EP CP C N
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVN 342
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
G + C C Y D E E ++ C C S+LC C GF
Sbjct: 343 TQGGFECHCYPNYDLV----DGE-CVEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFA 395
Query: 628 P 628
P
Sbjct: 396 P 396
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/88 (37%), Positives = 39/88 (44%), Gaps = 10/88 (11%)
Query: 763 FRCVCGPGYRPAGEV---CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
+ CVC G+ P C P CD NT S C C GY LD DG C
Sbjct: 386 YLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDP---NTQAS--CECPEGYILD-DGFIC 439
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSC 847
D+DECE C +C N G++EC C
Sbjct: 440 TDIDECENGGF-CSGVCHNLPGTFECIC 466
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 4/77 (5%)
Query: 783 ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQIC---SNT 839
+C+V C+ C+ G+ C C G L DG +C + C+ C +
Sbjct: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC-TASATQSCNDLCEHFCVPNPDQ 302
Query: 840 EGSYECSCEDGYEKRGD 856
GSY C CE GY D
Sbjct: 303 PGSYSCMCETGYRLAAD 319
Score = 45.2 bits (102), Expect = 0.001
Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 753 AIPGLCAPG-RFRCVCGPGY-RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLC 806
A P C P + C C GY G +C D+DEC C +CHN G+++C+C
Sbjct: 412 ACPADCDPNTQASCECPEGYILDDGFICTDIDECE-NGGFCSGVCHNLPGTFECIC 466
Score = 37.5 bits (83), Expect = 0.20
Identities = 35/104 (33%), Positives = 41/104 (39%), Gaps = 15/104 (14%)
Query: 18 QTKYLCCCSVG--------HAWGAPCE--ACPPRGSPAHTALCGEKPGEYINPVTNETKP 67
QT YLC C+ G H C ACP P A C E P YI
Sbjct: 383 QTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASC-ECPEGYILDDGFICTD 441
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVD 111
IDEC+ C G CH+ P F+C C G + H+ D D
Sbjct: 442 IDECE-NGGFCS-GVCHNLPGTFECIC--GPDSALARHIGTDCD 481
Score = 32.7 bits (71), Expect = 5.7
Identities = 16/44 (36%), Positives = 21/44 (47%), Gaps = 5/44 (11%)
Query: 744 VFADVDEC---AAIPGLC--APGRFRCVCGPGYRPAGEVCADVD 782
+ D+DEC G+C PG F C+CGP A + D D
Sbjct: 438 ICTDIDECENGGFCSGVCHNLPGTFECICGPDSALARHIGTDCD 481
>AL049651-2|CAB51954.1| 575|Homo sapiens thrombomodulin protein.
Length = 575
Score = 111 bits (267), Expect = 1e-23
Identities = 80/208 (38%), Positives = 99/208 (47%), Gaps = 24/208 (11%)
Query: 435 DVCVGGRCVNTD--GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYE 492
D+C N D GS+ C C GY LA D C D D+C L+P C C NT+GG+E
Sbjct: 290 DLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFE 348
Query: 493 CQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHN-TAGSFRCTCPYGYAVAADGVH-CR 549
C C P + D CV+ VD C RA+C ++C S+ C C G+A H C+
Sbjct: 349 CHCYPNYDL-VDGECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQ 405
Query: 550 DIDECVQEPRVCPHACE-NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSG 608
C Q CP C+ N S C+CPEGY D C DI+EC E CS
Sbjct: 406 MF--CNQ--TACPADCDPNTQAS--CECPEGY-----ILDDGFICTDIDEC-ENGGFCS- 452
Query: 609 GVCINTDGSFLCDCDAGFEPSED-GTDC 635
GVC N G+F C C + GTDC
Sbjct: 453 GVCHNLPGTFECICGPDSALARHIGTDC 480
Score = 99.5 bits (237), Expect = 4e-20
Identities = 95/310 (30%), Positives = 121/310 (39%), Gaps = 41/310 (13%)
Query: 30 AWGAPCEACPPRGSPAHTAL-----CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCH 84
A GA +A P S A L C PG E +C + C+ C+
Sbjct: 199 ARGADFQALPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CN 257
Query: 85 DTPTGFQCGCDHG--YEHDNTSHLCRDVDECSWGRPPCRGMAQCV---NLPGAFECRCPP 139
P +C C G + D S C+ C CV + PG++ C C
Sbjct: 258 AIPGAPRCQCPAGAALQADGRSCTASATQSCN---DLCEHF--CVPNPDQPGSYSCMCET 312
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVC-RDVDECSRP 198
GYRL CEDVD+C + C NT G + C C P Y L + C VD C R
Sbjct: 313 GYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRA 372
Query: 199 RPVCRNGTCENL-PGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC-----RNTV 252
C C+ L +YLC C +GF P+ + + C+ M C C NT
Sbjct: 373 N--CEY-QCQPLNQTSYLCVCAEGFAPIPH----EPHRCQ---MFCNQTACPADCDPNTQ 422
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
S CEC GY L DG C D+DEC+ G + C N G +EC CG L
Sbjct: 423 AS--CECPEGYILD-DGFICTDIDECEN-----GGFCSGVCHNLPGTFECICGPDSALAR 474
Query: 313 RRCVDRDECK 322
D D K
Sbjct: 475 HIGTDCDSGK 484
Score = 80.6 bits (190), Expect = 2e-14
Identities = 41/108 (37%), Positives = 55/108 (50%), Gaps = 6/108 (5%)
Query: 747 DVDECAAIPGLCAPGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNTDGSYDC 804
D+ E +P PG + C+C GYR A + C DVD+C + P PC Q C NT G ++C
Sbjct: 290 DLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFEC 349
Query: 805 LCRTGYELDEDGANCRDVDECERDTHTCQQICSN-TEGSYECSCEDGY 851
C Y+L DG VD C R C+ C + SY C C +G+
Sbjct: 350 HCYPNYDL-VDGECVEPVDPCFR--ANCEYQCQPLNQTSYLCVCAEGF 394
Score = 78.2 bits (184), Expect = 1e-13
Identities = 50/159 (31%), Positives = 68/159 (42%), Gaps = 12/159 (7%)
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNT-- 251
+CS C + C +PGA C C G + + + +C + N
Sbjct: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ 302
Query: 252 VGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
GS+ C C GY L AD C DVD+C P PC + C NT GG+EC C + LV
Sbjct: 303 PGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ----RCVNTQGGFECHCYPNYDLV 358
Query: 312 GRRCVDR-DECKELPYVCAGGECRNFN-GGYVCECPAGW 348
CV+ D C C +C+ N Y+C C G+
Sbjct: 359 DGECVEPVDPCFRAN--CE-YQCQPLNQTSYLCVCAEGF 394
Score = 77.8 bits (183), Expect = 2e-13
Identities = 72/246 (29%), Positives = 89/246 (36%), Gaps = 37/246 (15%)
Query: 333 CRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEG 392
C G C+CPAG C + C D E P Q C C G
Sbjct: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCE--HFCVPNPDQPGSYSCMCETG 313
Query: 393 AAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCE 452
RC +D+D+C + P C RCVNT G F C
Sbjct: 314 YRLAADQHRC----------------------EDVDDCILEPSPC-PQRCVNTQGGFECH 350
Query: 453 CPDGYVLAPDGLSCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVD 511
C Y L DG CV+ D C C + Y C C+ GF P +
Sbjct: 351 CYPNYDLV-DG-ECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQM 406
Query: 512 ECAEGRASCTFRCH-NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG 570
C + +C C NT S C CP GY + DG C DIDEC + C C N+ G
Sbjct: 407 FC--NQTACPADCDPNTQAS--CECPEGY-ILDDGFICTDIDEC-ENGGFCSGVCHNLPG 460
Query: 571 SYICKC 576
++ C C
Sbjct: 461 TFECIC 466
Score = 77.4 bits (182), Expect = 2e-13
Identities = 45/116 (38%), Positives = 54/116 (46%), Gaps = 15/116 (12%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCH-----NTD--GSYD 803
C AIPG AP R +C G + G C A C+ LC N D GSY
Sbjct: 256 CNAIPG--AP-RCQCPAGAALQADGRSCT-----ASATQSCNDLCEHFCVPNPDQPGSYS 307
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 859
C+C TGY L D C DVD+C + C Q C NT+G +EC C Y+ CV
Sbjct: 308 CMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECV 363
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/181 (28%), Positives = 67/181 (37%), Gaps = 11/181 (6%)
Query: 451 CECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDV 510
C P G V A +C+++ C + C+ G CQC G D
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTA 282
Query: 511 DECAEGRASCTFRC---HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN 567
C C + GS+ C C GY +AAD C D+D+C+ EP CP C N
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVN 342
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
G + C C Y D E E ++ C C S+LC C GF
Sbjct: 343 TQGGFECHCYPNYDLV----DGE-CVEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFA 395
Query: 628 P 628
P
Sbjct: 396 P 396
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/88 (37%), Positives = 39/88 (44%), Gaps = 10/88 (11%)
Query: 763 FRCVCGPGYRPAGEV---CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
+ CVC G+ P C P CD NT S C C GY LD DG C
Sbjct: 386 YLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDP---NTQAS--CECPEGYILD-DGFIC 439
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSC 847
D+DECE C +C N G++EC C
Sbjct: 440 TDIDECENGGF-CSGVCHNLPGTFECIC 466
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 4/77 (5%)
Query: 783 ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQIC---SNT 839
+C+V C+ C+ G+ C C G L DG +C + C+ C +
Sbjct: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC-TASATQSCNDLCEHFCVPNPDQ 302
Query: 840 EGSYECSCEDGYEKRGD 856
GSY C CE GY D
Sbjct: 303 PGSYSCMCETGYRLAAD 319
Score = 45.2 bits (102), Expect = 0.001
Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 753 AIPGLCAPG-RFRCVCGPGY-RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLC 806
A P C P + C C GY G +C D+DEC C +CHN G+++C+C
Sbjct: 412 ACPADCDPNTQASCECPEGYILDDGFICTDIDECE-NGGFCSGVCHNLPGTFECIC 466
Score = 37.5 bits (83), Expect = 0.20
Identities = 35/104 (33%), Positives = 41/104 (39%), Gaps = 15/104 (14%)
Query: 18 QTKYLCCCSVG--------HAWGAPCE--ACPPRGSPAHTALCGEKPGEYINPVTNETKP 67
QT YLC C+ G H C ACP P A C E P YI
Sbjct: 383 QTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASC-ECPEGYILDDGFICTD 441
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVD 111
IDEC+ C G CH+ P F+C C G + H+ D D
Sbjct: 442 IDECE-NGGFCS-GVCHNLPGTFECIC--GPDSALARHIGTDCD 481
Score = 32.7 bits (71), Expect = 5.7
Identities = 16/44 (36%), Positives = 21/44 (47%), Gaps = 5/44 (11%)
Query: 744 VFADVDEC---AAIPGLC--APGRFRCVCGPGYRPAGEVCADVD 782
+ D+DEC G+C PG F C+CGP A + D D
Sbjct: 438 ICTDIDECENGGFCSGVCHNLPGTFECICGPDSALARHIGTDCD 481
>AF495471-1|AAM03232.1| 575|Homo sapiens thrombomodulin protein.
Length = 575
Score = 111 bits (267), Expect = 1e-23
Identities = 80/208 (38%), Positives = 99/208 (47%), Gaps = 24/208 (11%)
Query: 435 DVCVGGRCVNTD--GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYE 492
D+C N D GS+ C C GY LA D C D D+C L+P C C NT+GG+E
Sbjct: 290 DLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFE 348
Query: 493 CQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHN-TAGSFRCTCPYGYAVAADGVH-CR 549
C C P + D CV+ VD C RA+C ++C S+ C C G+A H C+
Sbjct: 349 CHCYPNYDL-VDGECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQ 405
Query: 550 DIDECVQEPRVCPHACE-NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSG 608
C Q CP C+ N S C+CPEGY D C DI+EC E CS
Sbjct: 406 MF--CNQ--TACPADCDPNTQAS--CECPEGY-----ILDDGFICTDIDEC-ENGGFCS- 452
Query: 609 GVCINTDGSFLCDCDAGFEPSED-GTDC 635
GVC N G+F C C + GTDC
Sbjct: 453 GVCHNLPGTFECICGPDSALARHIGTDC 480
Score = 99.5 bits (237), Expect = 4e-20
Identities = 95/310 (30%), Positives = 121/310 (39%), Gaps = 41/310 (13%)
Query: 30 AWGAPCEACPPRGSPAHTAL-----CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCH 84
A GA +A P S A L C PG E +C + C+ C+
Sbjct: 199 ARGADFQALPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CN 257
Query: 85 DTPTGFQCGCDHG--YEHDNTSHLCRDVDECSWGRPPCRGMAQCV---NLPGAFECRCPP 139
P +C C G + D S C+ C CV + PG++ C C
Sbjct: 258 AIPGAPRCQCPAGAALQADGRSCTASATQSCN---DLCEHF--CVPNPDQPGSYSCMCET 312
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVC-RDVDECSRP 198
GYRL CEDVD+C + C NT G + C C P Y L + C VD C R
Sbjct: 313 GYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRA 372
Query: 199 RPVCRNGTCENL-PGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC-----RNTV 252
C C+ L +YLC C +GF P+ + + C+ M C C NT
Sbjct: 373 N--CEY-QCQPLNQTSYLCVCAEGFAPIPH----EPHRCQ---MFCNQTACPADCDPNTQ 422
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
S CEC GY L DG C D+DEC+ G + C N G +EC CG L
Sbjct: 423 AS--CECPEGYILD-DGFICTDIDECEN-----GGFCSGVCHNLPGTFECICGPDSALAR 474
Query: 313 RRCVDRDECK 322
D D K
Sbjct: 475 HIGTDCDSGK 484
Score = 80.6 bits (190), Expect = 2e-14
Identities = 41/108 (37%), Positives = 55/108 (50%), Gaps = 6/108 (5%)
Query: 747 DVDECAAIPGLCAPGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNTDGSYDC 804
D+ E +P PG + C+C GYR A + C DVD+C + P PC Q C NT G ++C
Sbjct: 290 DLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFEC 349
Query: 805 LCRTGYELDEDGANCRDVDECERDTHTCQQICSN-TEGSYECSCEDGY 851
C Y+L DG VD C R C+ C + SY C C +G+
Sbjct: 350 HCYPNYDL-VDGECVEPVDPCFR--ANCEYQCQPLNQTSYLCVCAEGF 394
Score = 78.2 bits (184), Expect = 1e-13
Identities = 50/159 (31%), Positives = 68/159 (42%), Gaps = 12/159 (7%)
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNT-- 251
+CS C + C +PGA C C G + + + +C + N
Sbjct: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ 302
Query: 252 VGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
GS+ C C GY L AD C DVD+C P PC + C NT GG+EC C + LV
Sbjct: 303 PGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ----RCVNTQGGFECHCYPNYDLV 358
Query: 312 GRRCVDR-DECKELPYVCAGGECRNFN-GGYVCECPAGW 348
CV+ D C C +C+ N Y+C C G+
Sbjct: 359 DGECVEPVDPCFRAN--CE-YQCQPLNQTSYLCVCAEGF 394
Score = 77.8 bits (183), Expect = 2e-13
Identities = 72/246 (29%), Positives = 89/246 (36%), Gaps = 37/246 (15%)
Query: 333 CRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEG 392
C G C+CPAG C + C D E P Q C C G
Sbjct: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCE--HFCVPNPDQPGSYSCMCETG 313
Query: 393 AAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCE 452
RC +D+D+C + P C RCVNT G F C
Sbjct: 314 YRLAADQHRC----------------------EDVDDCILEPSPC-PQRCVNTQGGFECH 350
Query: 453 CPDGYVLAPDGLSCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVD 511
C Y L DG CV+ D C C + Y C C+ GF P +
Sbjct: 351 CYPNYDLV-DG-ECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQM 406
Query: 512 ECAEGRASCTFRCH-NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG 570
C + +C C NT S C CP GY + DG C DIDEC + C C N+ G
Sbjct: 407 FC--NQTACPADCDPNTQAS--CECPEGY-ILDDGFICTDIDEC-ENGGFCSGVCHNLPG 460
Query: 571 SYICKC 576
++ C C
Sbjct: 461 TFECIC 466
Score = 77.4 bits (182), Expect = 2e-13
Identities = 45/116 (38%), Positives = 54/116 (46%), Gaps = 15/116 (12%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCH-----NTD--GSYD 803
C AIPG AP R +C G + G C A C+ LC N D GSY
Sbjct: 256 CNAIPG--AP-RCQCPAGAALQADGRSCT-----ASATQSCNDLCEHFCVPNPDQPGSYS 307
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 859
C+C TGY L D C DVD+C + C Q C NT+G +EC C Y+ CV
Sbjct: 308 CMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECV 363
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/181 (28%), Positives = 67/181 (37%), Gaps = 11/181 (6%)
Query: 451 CECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDV 510
C P G V A +C+++ C + C+ G CQC G D
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTA 282
Query: 511 DECAEGRASCTFRC---HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN 567
C C + GS+ C C GY +AAD C D+D+C+ EP CP C N
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVN 342
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
G + C C Y D E E ++ C C S+LC C GF
Sbjct: 343 TQGGFECHCYPNYDLV----DGE-CVEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFA 395
Query: 628 P 628
P
Sbjct: 396 P 396
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/88 (37%), Positives = 39/88 (44%), Gaps = 10/88 (11%)
Query: 763 FRCVCGPGYRPAGEV---CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
+ CVC G+ P C P CD NT S C C GY LD DG C
Sbjct: 386 YLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDP---NTQAS--CECPEGYILD-DGFIC 439
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSC 847
D+DECE C +C N G++EC C
Sbjct: 440 TDIDECENGGF-CSGVCHNLPGTFECIC 466
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 4/77 (5%)
Query: 783 ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQIC---SNT 839
+C+V C+ C+ G+ C C G L DG +C + C+ C +
Sbjct: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC-TASATQSCNDLCEHFCVPNPDQ 302
Query: 840 EGSYECSCEDGYEKRGD 856
GSY C CE GY D
Sbjct: 303 PGSYSCMCETGYRLAAD 319
Score = 45.2 bits (102), Expect = 0.001
Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 753 AIPGLCAPG-RFRCVCGPGY-RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLC 806
A P C P + C C GY G +C D+DEC C +CHN G+++C+C
Sbjct: 412 ACPADCDPNTQASCECPEGYILDDGFICTDIDECE-NGGFCSGVCHNLPGTFECIC 466
Score = 37.5 bits (83), Expect = 0.20
Identities = 35/104 (33%), Positives = 41/104 (39%), Gaps = 15/104 (14%)
Query: 18 QTKYLCCCSVG--------HAWGAPCE--ACPPRGSPAHTALCGEKPGEYINPVTNETKP 67
QT YLC C+ G H C ACP P A C E P YI
Sbjct: 383 QTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASC-ECPEGYILDDGFICTD 441
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVD 111
IDEC+ C G CH+ P F+C C G + H+ D D
Sbjct: 442 IDECE-NGGFCS-GVCHNLPGTFECIC--GPDSALARHIGTDCD 481
Score = 32.7 bits (71), Expect = 5.7
Identities = 16/44 (36%), Positives = 21/44 (47%), Gaps = 5/44 (11%)
Query: 744 VFADVDEC---AAIPGLC--APGRFRCVCGPGYRPAGEVCADVD 782
+ D+DEC G+C PG F C+CGP A + D D
Sbjct: 438 ICTDIDECENGGFCSGVCHNLPGTFECICGPDSALARHIGTDCD 481
>X05495-1|CAA29045.1| 575|Homo sapiens thrombomodulin protein.
Length = 575
Score = 110 bits (264), Expect = 2e-23
Identities = 81/209 (38%), Positives = 100/209 (47%), Gaps = 26/209 (12%)
Query: 435 DVCVGGRCVNTD--GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYE 492
D+C N D GS+ C C GY LA D C D D+C L+P C C NT+GG+E
Sbjct: 290 DLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFE 348
Query: 493 CQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHN-TAGSFRCTCPYGYAVAADGVH-CR 549
C C P + D CV+ VD C RA+C ++C S+ C C G+A H C+
Sbjct: 349 CHCYPNYDL-VDGECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQ 405
Query: 550 DIDECVQEPRVCPHACE-NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSG 608
C Q CP C+ N S C+CPEGY D C DI+EC E CS
Sbjct: 406 MF--CNQ--TACPADCDPNTQAS--CECPEGY-----ILDDGFICTDIDEC-ENGGFCS- 452
Query: 609 GVCINTDGSFLCDC--DAGFEPSEDGTDC 635
GVC N G+F C C D+ GTDC
Sbjct: 453 GVCHNLPGTFECICGPDSAL-VRHIGTDC 480
Score = 101 bits (241), Expect = 1e-20
Identities = 96/310 (30%), Positives = 122/310 (39%), Gaps = 41/310 (13%)
Query: 30 AWGAPCEACPPRGSPAHTAL-----CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCH 84
A GA +A P S A L C PG E +C + C+ C+
Sbjct: 199 ARGADFQALPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CN 257
Query: 85 DTPTGFQCGCDHG--YEHDNTSHLCRDVDECSWGRPPCRGMAQCV---NLPGAFECRCPP 139
P +C C G + D S C+ C CV + PG++ C C
Sbjct: 258 AIPGAPRCQCPAGAALQADGRSCTASATQSCN---DLCEHF--CVPNPDQPGSYSCMCET 312
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVC-RDVDECSRP 198
GYRL CEDVD+C + C NT G + C C P Y L + C VD C R
Sbjct: 313 GYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRA 372
Query: 199 RPVCRNGTCENL-PGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC-----RNTV 252
C C+ L +YLC C +GF P+ + + C+ M C C NT
Sbjct: 373 N--CEY-QCQPLNQTSYLCVCAEGFAPIPH----EPHRCQ---MFCNQTACPADCDPNTQ 422
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
S CEC GY L DG C D+DEC+ G + C N G +EC CG LV
Sbjct: 423 AS--CECPEGYILD-DGFICTDIDECEN-----GGFCSGVCHNLPGTFECICGPDSALVR 474
Query: 313 RRCVDRDECK 322
D D K
Sbjct: 475 HIGTDCDSGK 484
Score = 80.6 bits (190), Expect = 2e-14
Identities = 41/108 (37%), Positives = 55/108 (50%), Gaps = 6/108 (5%)
Query: 747 DVDECAAIPGLCAPGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNTDGSYDC 804
D+ E +P PG + C+C GYR A + C DVD+C + P PC Q C NT G ++C
Sbjct: 290 DLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFEC 349
Query: 805 LCRTGYELDEDGANCRDVDECERDTHTCQQICSN-TEGSYECSCEDGY 851
C Y+L DG VD C R C+ C + SY C C +G+
Sbjct: 350 HCYPNYDL-VDGECVEPVDPCFR--ANCEYQCQPLNQTSYLCVCAEGF 394
Score = 78.2 bits (184), Expect = 1e-13
Identities = 50/159 (31%), Positives = 68/159 (42%), Gaps = 12/159 (7%)
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNT-- 251
+CS C + C +PGA C C G + + + +C + N
Sbjct: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ 302
Query: 252 VGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
GS+ C C GY L AD C DVD+C P PC + C NT GG+EC C + LV
Sbjct: 303 PGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ----RCVNTQGGFECHCYPNYDLV 358
Query: 312 GRRCVDR-DECKELPYVCAGGECRNFN-GGYVCECPAGW 348
CV+ D C C +C+ N Y+C C G+
Sbjct: 359 DGECVEPVDPCFRAN--CE-YQCQPLNQTSYLCVCAEGF 394
Score = 77.8 bits (183), Expect = 2e-13
Identities = 72/246 (29%), Positives = 89/246 (36%), Gaps = 37/246 (15%)
Query: 333 CRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEG 392
C G C+CPAG C + C D E P Q C C G
Sbjct: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCE--HFCVPNPDQPGSYSCMCETG 313
Query: 393 AAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCE 452
RC +D+D+C + P C RCVNT G F C
Sbjct: 314 YRLAADQHRC----------------------EDVDDCILEPSPC-PQRCVNTQGGFECH 350
Query: 453 CPDGYVLAPDGLSCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVD 511
C Y L DG CV+ D C C + Y C C+ GF P +
Sbjct: 351 CYPNYDLV-DG-ECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQM 406
Query: 512 ECAEGRASCTFRCH-NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG 570
C + +C C NT S C CP GY + DG C DIDEC + C C N+ G
Sbjct: 407 FC--NQTACPADCDPNTQAS--CECPEGY-ILDDGFICTDIDEC-ENGGFCSGVCHNLPG 460
Query: 571 SYICKC 576
++ C C
Sbjct: 461 TFECIC 466
Score = 77.4 bits (182), Expect = 2e-13
Identities = 45/116 (38%), Positives = 54/116 (46%), Gaps = 15/116 (12%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCH-----NTD--GSYD 803
C AIPG AP R +C G + G C A C+ LC N D GSY
Sbjct: 256 CNAIPG--AP-RCQCPAGAALQADGRSCT-----ASATQSCNDLCEHFCVPNPDQPGSYS 307
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 859
C+C TGY L D C DVD+C + C Q C NT+G +EC C Y+ CV
Sbjct: 308 CMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECV 363
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/181 (28%), Positives = 67/181 (37%), Gaps = 11/181 (6%)
Query: 451 CECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDV 510
C P G V A +C+++ C + C+ G CQC G D
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTA 282
Query: 511 DECAEGRASCTFRC---HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN 567
C C + GS+ C C GY +AAD C D+D+C+ EP CP C N
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVN 342
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
G + C C Y D E E ++ C C S+LC C GF
Sbjct: 343 TQGGFECHCYPNYDLV----DGE-CVEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFA 395
Query: 628 P 628
P
Sbjct: 396 P 396
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/88 (37%), Positives = 39/88 (44%), Gaps = 10/88 (11%)
Query: 763 FRCVCGPGYRPAGEV---CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
+ CVC G+ P C P CD NT S C C GY LD DG C
Sbjct: 386 YLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDP---NTQAS--CECPEGYILD-DGFIC 439
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSC 847
D+DECE C +C N G++EC C
Sbjct: 440 TDIDECENGGF-CSGVCHNLPGTFECIC 466
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 4/77 (5%)
Query: 783 ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQIC---SNT 839
+C+V C+ C+ G+ C C G L DG +C + C+ C +
Sbjct: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC-TASATQSCNDLCEHFCVPNPDQ 302
Query: 840 EGSYECSCEDGYEKRGD 856
GSY C CE GY D
Sbjct: 303 PGSYSCMCETGYRLAAD 319
Score = 45.2 bits (102), Expect = 0.001
Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 753 AIPGLCAPG-RFRCVCGPGY-RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLC 806
A P C P + C C GY G +C D+DEC C +CHN G+++C+C
Sbjct: 412 ACPADCDPNTQASCECPEGYILDDGFICTDIDECE-NGGFCSGVCHNLPGTFECIC 466
Score = 37.5 bits (83), Expect = 0.20
Identities = 35/104 (33%), Positives = 41/104 (39%), Gaps = 15/104 (14%)
Query: 18 QTKYLCCCSVG--------HAWGAPCE--ACPPRGSPAHTALCGEKPGEYINPVTNETKP 67
QT YLC C+ G H C ACP P A C E P YI
Sbjct: 383 QTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASC-ECPEGYILDDGFICTD 441
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVD 111
IDEC+ C G CH+ P F+C C G + H+ D D
Sbjct: 442 IDECE-NGGFCS-GVCHNLPGTFECIC--GPDSALVRHIGTDCD 481
>D00210-1|BAA00149.1| 575|Homo sapiens thrombomodulin precursor
protein.
Length = 575
Score = 110 bits (264), Expect = 2e-23
Identities = 81/209 (38%), Positives = 100/209 (47%), Gaps = 26/209 (12%)
Query: 435 DVCVGGRCVNTD--GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYE 492
D+C N D GS+ C C GY LA D C D D+C L+P C C NT+GG+E
Sbjct: 290 DLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFE 348
Query: 493 CQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHN-TAGSFRCTCPYGYAVAADGVH-CR 549
C C P + D CV+ VD C RA+C ++C S+ C C G+A H C+
Sbjct: 349 CHCYPNYDL-VDGECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQ 405
Query: 550 DIDECVQEPRVCPHACE-NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSG 608
C Q CP C+ N S C+CPEGY D C DI+EC E CS
Sbjct: 406 MF--CNQ--TACPADCDPNTQAS--CECPEGY-----ILDDGFICTDIDEC-ENGGFCS- 452
Query: 609 GVCINTDGSFLCDC--DAGFEPSEDGTDC 635
GVC N G+F C C D+ GTDC
Sbjct: 453 GVCHNLPGTFECICGPDSAL-VRHIGTDC 480
Score = 101 bits (241), Expect = 1e-20
Identities = 96/310 (30%), Positives = 122/310 (39%), Gaps = 41/310 (13%)
Query: 30 AWGAPCEACPPRGSPAHTAL-----CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCH 84
A GA +A P S A L C PG E +C + C+ C+
Sbjct: 199 ARGADFQALPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CN 257
Query: 85 DTPTGFQCGCDHG--YEHDNTSHLCRDVDECSWGRPPCRGMAQCV---NLPGAFECRCPP 139
P +C C G + D S C+ C CV + PG++ C C
Sbjct: 258 AIPGAPRCQCPAGAALQADGRSCTASATQSCN---DLCEHF--CVPNPDQPGSYSCMCET 312
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVC-RDVDECSRP 198
GYRL CEDVD+C + C NT G + C C P Y L + C VD C R
Sbjct: 313 GYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRA 372
Query: 199 RPVCRNGTCENL-PGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC-----RNTV 252
C C+ L +YLC C +GF P+ + + C+ M C C NT
Sbjct: 373 N--CEY-QCQPLNQTSYLCVCAEGFAPIPH----EPHRCQ---MFCNQTACPADCDPNTQ 422
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
S CEC GY L DG C D+DEC+ G + C N G +EC CG LV
Sbjct: 423 AS--CECPEGYILD-DGFICTDIDECEN-----GGFCSGVCHNLPGTFECICGPDSALVR 474
Query: 313 RRCVDRDECK 322
D D K
Sbjct: 475 HIGTDCDSGK 484
Score = 80.6 bits (190), Expect = 2e-14
Identities = 41/108 (37%), Positives = 55/108 (50%), Gaps = 6/108 (5%)
Query: 747 DVDECAAIPGLCAPGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNTDGSYDC 804
D+ E +P PG + C+C GYR A + C DVD+C + P PC Q C NT G ++C
Sbjct: 290 DLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFEC 349
Query: 805 LCRTGYELDEDGANCRDVDECERDTHTCQQICSN-TEGSYECSCEDGY 851
C Y+L DG VD C R C+ C + SY C C +G+
Sbjct: 350 HCYPNYDL-VDGECVEPVDPCFR--ANCEYQCQPLNQTSYLCVCAEGF 394
Score = 78.2 bits (184), Expect = 1e-13
Identities = 50/159 (31%), Positives = 68/159 (42%), Gaps = 12/159 (7%)
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNT-- 251
+CS C + C +PGA C C G + + + +C + N
Sbjct: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ 302
Query: 252 VGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
GS+ C C GY L AD C DVD+C P PC + C NT GG+EC C + LV
Sbjct: 303 PGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ----RCVNTQGGFECHCYPNYDLV 358
Query: 312 GRRCVDR-DECKELPYVCAGGECRNFN-GGYVCECPAGW 348
CV+ D C C +C+ N Y+C C G+
Sbjct: 359 DGECVEPVDPCFRAN--CE-YQCQPLNQTSYLCVCAEGF 394
Score = 77.8 bits (183), Expect = 2e-13
Identities = 72/246 (29%), Positives = 89/246 (36%), Gaps = 37/246 (15%)
Query: 333 CRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEG 392
C G C+CPAG C + C D E P Q C C G
Sbjct: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCE--HFCVPNPDQPGSYSCMCETG 313
Query: 393 AAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCE 452
RC +D+D+C + P C RCVNT G F C
Sbjct: 314 YRLAADQHRC----------------------EDVDDCILEPSPC-PQRCVNTQGGFECH 350
Query: 453 CPDGYVLAPDGLSCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVD 511
C Y L DG CV+ D C C + Y C C+ GF P +
Sbjct: 351 CYPNYDLV-DG-ECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQM 406
Query: 512 ECAEGRASCTFRCH-NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG 570
C + +C C NT S C CP GY + DG C DIDEC + C C N+ G
Sbjct: 407 FC--NQTACPADCDPNTQAS--CECPEGY-ILDDGFICTDIDEC-ENGGFCSGVCHNLPG 460
Query: 571 SYICKC 576
++ C C
Sbjct: 461 TFECIC 466
Score = 77.4 bits (182), Expect = 2e-13
Identities = 45/116 (38%), Positives = 54/116 (46%), Gaps = 15/116 (12%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCH-----NTD--GSYD 803
C AIPG AP R +C G + G C A C+ LC N D GSY
Sbjct: 256 CNAIPG--AP-RCQCPAGAALQADGRSCT-----ASATQSCNDLCEHFCVPNPDQPGSYS 307
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 859
C+C TGY L D C DVD+C + C Q C NT+G +EC C Y+ CV
Sbjct: 308 CMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECV 363
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/181 (28%), Positives = 67/181 (37%), Gaps = 11/181 (6%)
Query: 451 CECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDV 510
C P G V A +C+++ C + C+ G CQC G D
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTA 282
Query: 511 DECAEGRASCTFRC---HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN 567
C C + GS+ C C GY +AAD C D+D+C+ EP CP C N
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVN 342
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
G + C C Y D E E ++ C C S+LC C GF
Sbjct: 343 TQGGFECHCYPNYDLV----DGE-CVEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFA 395
Query: 628 P 628
P
Sbjct: 396 P 396
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/88 (37%), Positives = 39/88 (44%), Gaps = 10/88 (11%)
Query: 763 FRCVCGPGYRPAGEV---CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
+ CVC G+ P C P CD NT S C C GY LD DG C
Sbjct: 386 YLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDP---NTQAS--CECPEGYILD-DGFIC 439
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSC 847
D+DECE C +C N G++EC C
Sbjct: 440 TDIDECENGGF-CSGVCHNLPGTFECIC 466
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 4/77 (5%)
Query: 783 ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQIC---SNT 839
+C+V C+ C+ G+ C C G L DG +C + C+ C +
Sbjct: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC-TASATQSCNDLCEHFCVPNPDQ 302
Query: 840 EGSYECSCEDGYEKRGD 856
GSY C CE GY D
Sbjct: 303 PGSYSCMCETGYRLAAD 319
Score = 45.2 bits (102), Expect = 0.001
Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 753 AIPGLCAPG-RFRCVCGPGY-RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLC 806
A P C P + C C GY G +C D+DEC C +CHN G+++C+C
Sbjct: 412 ACPADCDPNTQASCECPEGYILDDGFICTDIDECE-NGGFCSGVCHNLPGTFECIC 466
Score = 37.5 bits (83), Expect = 0.20
Identities = 35/104 (33%), Positives = 41/104 (39%), Gaps = 15/104 (14%)
Query: 18 QTKYLCCCSVG--------HAWGAPCE--ACPPRGSPAHTALCGEKPGEYINPVTNETKP 67
QT YLC C+ G H C ACP P A C E P YI
Sbjct: 383 QTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASC-ECPEGYILDDGFICTD 441
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVD 111
IDEC+ C G CH+ P F+C C G + H+ D D
Sbjct: 442 IDECE-NGGFCS-GVCHNLPGTFECIC--GPDSALVRHIGTDCD 481
>BC035602-1|AAH35602.2| 575|Homo sapiens thrombomodulin protein.
Length = 575
Score = 110 bits (264), Expect = 2e-23
Identities = 81/209 (38%), Positives = 100/209 (47%), Gaps = 26/209 (12%)
Query: 435 DVCVGGRCVNTD--GSFRCECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYE 492
D+C N D GS+ C C GY LA D C D D+C L+P C C NT+GG+E
Sbjct: 290 DLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFE 348
Query: 493 CQCSPGFTQGPDQTCVD-VDECAEGRASCTFRCHN-TAGSFRCTCPYGYAVAADGVH-CR 549
C C P + D CV+ VD C RA+C ++C S+ C C G+A H C+
Sbjct: 349 CHCYPNYDL-VDGECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQ 405
Query: 550 DIDECVQEPRVCPHACE-NVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSG 608
C Q CP C+ N S C+CPEGY D C DI+EC E CS
Sbjct: 406 MF--CNQ--TACPADCDPNTQAS--CECPEGY-----ILDDGFICTDIDEC-ENGGFCS- 452
Query: 609 GVCINTDGSFLCDC--DAGFEPSEDGTDC 635
GVC N G+F C C D+ GTDC
Sbjct: 453 GVCHNLPGTFECICGPDSAL-VRHIGTDC 480
Score = 101 bits (241), Expect = 1e-20
Identities = 96/310 (30%), Positives = 122/310 (39%), Gaps = 41/310 (13%)
Query: 30 AWGAPCEACPPRGSPAHTAL-----CGEKPGEYINPVTNETKPIDECDIMPQLCKPGTCH 84
A GA +A P S A L C PG E +C + C+ C+
Sbjct: 199 ARGADFQALPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CN 257
Query: 85 DTPTGFQCGCDHG--YEHDNTSHLCRDVDECSWGRPPCRGMAQCV---NLPGAFECRCPP 139
P +C C G + D S C+ C CV + PG++ C C
Sbjct: 258 AIPGAPRCQCPAGAALQADGRSCTASATQSCN---DLCEHF--CVPNPDQPGSYSCMCET 312
Query: 140 GYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENVC-RDVDECSRP 198
GYRL CEDVD+C + C NT G + C C P Y L + C VD C R
Sbjct: 313 GYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRA 372
Query: 199 RPVCRNGTCENL-PGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRC-----RNTV 252
C C+ L +YLC C +GF P+ + + C+ M C C NT
Sbjct: 373 N--CEY-QCQPLNQTSYLCVCAEGFAPIPH----EPHRCQ---MFCNQTACPADCDPNTQ 422
Query: 253 GSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVG 312
S CEC GY L DG C D+DEC+ G + C N G +EC CG LV
Sbjct: 423 AS--CECPEGYILD-DGFICTDIDECEN-----GGFCSGVCHNLPGTFECICGPDSALVR 474
Query: 313 RRCVDRDECK 322
D D K
Sbjct: 475 HIGTDCDSGK 484
Score = 80.6 bits (190), Expect = 2e-14
Identities = 41/108 (37%), Positives = 55/108 (50%), Gaps = 6/108 (5%)
Query: 747 DVDECAAIPGLCAPGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNTDGSYDC 804
D+ E +P PG + C+C GYR A + C DVD+C + P PC Q C NT G ++C
Sbjct: 290 DLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFEC 349
Query: 805 LCRTGYELDEDGANCRDVDECERDTHTCQQICSN-TEGSYECSCEDGY 851
C Y+L DG VD C R C+ C + SY C C +G+
Sbjct: 350 HCYPNYDL-VDGECVEPVDPCFR--ANCEYQCQPLNQTSYLCVCAEGF 394
Score = 78.2 bits (184), Expect = 1e-13
Identities = 50/159 (31%), Positives = 68/159 (42%), Gaps = 12/159 (7%)
Query: 194 ECSRPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNGRCRNT-- 251
+CS C + C +PGA C C G + + + +C + N
Sbjct: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ 302
Query: 252 VGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLV 311
GS+ C C GY L AD C DVD+C P PC + C NT GG+EC C + LV
Sbjct: 303 PGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ----RCVNTQGGFECHCYPNYDLV 358
Query: 312 GRRCVDR-DECKELPYVCAGGECRNFN-GGYVCECPAGW 348
CV+ D C C +C+ N Y+C C G+
Sbjct: 359 DGECVEPVDPCFRAN--CE-YQCQPLNQTSYLCVCAEGF 394
Score = 77.8 bits (183), Expect = 2e-13
Identities = 72/246 (29%), Positives = 89/246 (36%), Gaps = 37/246 (15%)
Query: 333 CRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEG 392
C G C+CPAG C + C D E P Q C C G
Sbjct: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCE--HFCVPNPDQPGSYSCMCETG 313
Query: 393 AAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCE 452
RC +D+D+C + P C RCVNT G F C
Sbjct: 314 YRLAADQHRC----------------------EDVDDCILEPSPC-PQRCVNTQGGFECH 350
Query: 453 CPDGYVLAPDGLSCVD-ADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDVD 511
C Y L DG CV+ D C C + Y C C+ GF P +
Sbjct: 351 CYPNYDLV-DG-ECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQM 406
Query: 512 ECAEGRASCTFRCH-NTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVG 570
C + +C C NT S C CP GY + DG C DIDEC + C C N+ G
Sbjct: 407 FC--NQTACPADCDPNTQAS--CECPEGY-ILDDGFICTDIDEC-ENGGFCSGVCHNLPG 460
Query: 571 SYICKC 576
++ C C
Sbjct: 461 TFECIC 466
Score = 77.4 bits (182), Expect = 2e-13
Identities = 45/116 (38%), Positives = 54/116 (46%), Gaps = 15/116 (12%)
Query: 751 CAAIPGLCAPGRFRCVCGPGYRPAGEVCADVDECAVRPPPCDQLCH-----NTD--GSYD 803
C AIPG AP R +C G + G C A C+ LC N D GSY
Sbjct: 256 CNAIPG--AP-RCQCPAGAALQADGRSCT-----ASATQSCNDLCEHFCVPNPDQPGSYS 307
Query: 804 CLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 859
C+C TGY L D C DVD+C + C Q C NT+G +EC C Y+ CV
Sbjct: 308 CMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECV 363
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/181 (28%), Positives = 67/181 (37%), Gaps = 11/181 (6%)
Query: 451 CECPDGYVLAPDGLSCVDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTCVDV 510
C P G V A +C+++ C + C+ G CQC G D
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTA 282
Query: 511 DECAEGRASCTFRC---HNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN 567
C C + GS+ C C GY +AAD C D+D+C+ EP CP C N
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVN 342
Query: 568 VVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDGSFLCDCDAGFE 627
G + C C Y D E E ++ C C S+LC C GF
Sbjct: 343 TQGGFECHCYPNYDLV----DGE-CVEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFA 395
Query: 628 P 628
P
Sbjct: 396 P 396
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/88 (37%), Positives = 39/88 (44%), Gaps = 10/88 (11%)
Query: 763 FRCVCGPGYRPAGEV---CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 819
+ CVC G+ P C P CD NT S C C GY LD DG C
Sbjct: 386 YLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDP---NTQAS--CECPEGYILD-DGFIC 439
Query: 820 RDVDECERDTHTCQQICSNTEGSYECSC 847
D+DECE C +C N G++EC C
Sbjct: 440 TDIDECENGGF-CSGVCHNLPGTFECIC 466
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 4/77 (5%)
Query: 783 ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQIC---SNT 839
+C+V C+ C+ G+ C C G L DG +C + C+ C +
Sbjct: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC-TASATQSCNDLCEHFCVPNPDQ 302
Query: 840 EGSYECSCEDGYEKRGD 856
GSY C CE GY D
Sbjct: 303 PGSYSCMCETGYRLAAD 319
Score = 45.2 bits (102), Expect = 0.001
Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 753 AIPGLCAPG-RFRCVCGPGY-RPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLC 806
A P C P + C C GY G +C D+DEC C +CHN G+++C+C
Sbjct: 412 ACPADCDPNTQASCECPEGYILDDGFICTDIDECE-NGGFCSGVCHNLPGTFECIC 466
Score = 37.5 bits (83), Expect = 0.20
Identities = 35/104 (33%), Positives = 41/104 (39%), Gaps = 15/104 (14%)
Query: 18 QTKYLCCCSVG--------HAWGAPCE--ACPPRGSPAHTALCGEKPGEYINPVTNETKP 67
QT YLC C+ G H C ACP P A C E P YI
Sbjct: 383 QTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASC-ECPEGYILDDGFICTD 441
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVD 111
IDEC+ C G CH+ P F+C C G + H+ D D
Sbjct: 442 IDECE-NGGFCS-GVCHNLPGTFECIC--GPDSALVRHIGTDCD 481
>AL513325-2|CAM17208.1| 1294|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1294
Score = 105 bits (253), Expect = 5e-22
Identities = 98/292 (33%), Positives = 128/292 (43%), Gaps = 51/292 (17%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS--WGRPPCRGMAQCVNLPG--AFECRC 137
TC D C C D ++L +D D PC+G A CVN PG +F C+C
Sbjct: 44 TCKDFSKDNDCSCS-----DTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKC 98
Query: 138 PPGYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYR-CECKPGYTLRENVCR-DVDE 194
PPGY T CE + CG + C HG + Y C C GY R C D DE
Sbjct: 99 PPGYSGTI----CETTIGSCG-KNSCQHGGICHQDPIYPVCICPAGYAGR--FCEIDHDE 151
Query: 195 CSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTV 252
C+ C+NG C++ Y C C G++ G + D ++V+EC C+N C N +
Sbjct: 152 CASSP--CQNGAVCQDGIDGYSCFCVPGYQ-GRHCD-LEVDECASDP--CKNEATCLNEI 205
Query: 253 GSFRCECAPGYTLTADGRNCR-DVDECDELP----HPC---------GR-DGNPSCTNTN 297
G + C C Y+ G C D++EC+ P C GR G PS + +
Sbjct: 206 GRYTCICPHNYS-GYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYH 264
Query: 298 --GGYECSCGAGWKLVGRRCV-DRDECKELPYVCA-GGECRNFNGGYVCECP 345
GY C C G+ G C D +EC P C GG C N G Y C CP
Sbjct: 265 EASGYVCICQPGF--TGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHCP 312
Score = 88.6 bits (210), Expect = 8e-17
Identities = 94/357 (26%), Positives = 137/357 (38%), Gaps = 52/357 (14%)
Query: 163 DHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPG--AYLCHCDD 220
++ C++ C C + C ++ + P + TC N PG ++LC C
Sbjct: 41 NNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPP 100
Query: 221 GFKAGPNNDCV---DVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVD 276
G+ + N C+ GG +C C C GY GR C D D
Sbjct: 101 GYSGTICETTIGSCGKNSCQHGG-ICHQDPIYPV-----CICPAGYA----GRFCEIDHD 150
Query: 277 ECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECR 334
EC PC C + GY C C G++ GR C ++ DEC P C C
Sbjct: 151 EC--ASSPC--QNGAVCQDGIDGYSCFCVPGYQ--GRHCDLEVDECASDP--CKNEATCL 202
Query: 335 NFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECC-CSEGA 393
N G Y C CP + T A C E + C+ + P Q + EC S
Sbjct: 203 NEIGRYTCICPHNYS-GYTGAQC----------EIDLNECN-SNPCQ-SNGECVELSSEK 249
Query: 394 AWGRYC---ERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSF 449
+GR +++ ++ ICQ G + +D++EC P C GG C N G++
Sbjct: 250 QYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNY 307
Query: 450 RCECPDGYVLAP--DGLSCVDADECALDPRICGNGTC----SNTRGGYECQCSPGFT 500
C CP + G C D + NGTC + + G+ C C G+T
Sbjct: 308 TCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYT 364
Score = 88.6 bits (210), Expect = 8e-17
Identities = 64/216 (29%), Positives = 93/216 (43%), Gaps = 27/216 (12%)
Query: 107 CRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG 165
C ++ C+ PC C ++ ++ C CP G+ S CE ++DEC C HG
Sbjct: 1025 CLQLNVCNSN--PCLHGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECFSNP-CIHG 1077
Query: 166 DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKA 224
+C + + +Y C C+PGYT N D+D C + C NG TC + Y C C F
Sbjct: 1078 NCSDRVAAYHCTCEPGYT-GVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLCFGNFTG 1134
Query: 225 G-PNNDCVDVNEC--REGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECD 279
+ C + + C N G C +C C PG+T G C +D+DEC
Sbjct: 1135 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT----GEWCEKDIDEC- 1189
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
PC G C + ++C C + G RC
Sbjct: 1190 -ASDPCVNGG--LCQDLLNKFQCLCDVAF--AGERC 1220
Score = 80.2 bits (189), Expect = 3e-14
Identities = 103/375 (27%), Positives = 142/375 (37%), Gaps = 85/375 (22%)
Query: 290 NPSCTNTNGGYECSCGAGWKLVGRRCVD-RDECKELPYVCAGGE-CRNFNG--GYVCECP 345
N +C + + +CSC + + C + +D C P C G C N G ++C+CP
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNP--CQGSATCVNTPGERSFLCKCP 99
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
G+ K C G CH+ P+ P C C G A
Sbjct: 100 PGYSGTICETTIGSCGKNSCQ---HGGICHQD-PIY---PVCICPAGYAG---------- 142
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGL 464
R C+ D DEC P C G C + + C C GY G
Sbjct: 143 ------RFCE---------IDHDECASSP--CQNGAVCQDGIDGYSCFCVPGY----QGR 181
Query: 465 SC-VDADECALDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTC-VDVDEC----AEGR 517
C ++ DECA DP C N TC N G Y C C ++ C +D++EC +
Sbjct: 182 HCDLEVDECASDP--CKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSN 239
Query: 518 ASC-----------------TFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPR 559
C +F H +G + C C G+ G+HC D++EC P
Sbjct: 240 GECVELSSEKQYGRITGLPSSFSYHEASG-YVCICQPGFT----GIHCEEDVNECSSNPC 294
Query: 560 VCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDI-NECEEQEDLCSGGVCIN--TDG 616
CEN+ G+Y C CP + S C DI C Q+ L + G CI DG
Sbjct: 295 QNGGTCENLPGNYTCHCP--FDNLSRTFYGGRDCSDILLGCTHQQCL-NNGTCIPHFQDG 351
Query: 617 --SFLCDCDAGFEPS 629
F C C +G+ S
Sbjct: 352 QHGFSCLCPSGYTGS 366
Score = 80.2 bits (189), Expect = 3e-14
Identities = 79/258 (30%), Positives = 104/258 (40%), Gaps = 47/258 (18%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
G CH P C C GY C D DEC+ PC+ A C + + C C P
Sbjct: 123 GICHQDPIYPVCICPAGY----AGRFCEIDHDECA--SSPCQNGAVCQDGIDGYSCFCVP 176
Query: 140 GYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECK---PGYT-------LRE-- 186
GY+ C+ +VDEC + C N IG Y C C GYT L E
Sbjct: 177 GYQGR----HCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNECN 232
Query: 187 -NVCRDVDECSRPRPVCRNGTCENLPGA--------YLCHCDDGFKAGPNNDCVDVNECR 237
N C+ EC + G LP + Y+C C GF G + + DVNEC
Sbjct: 233 SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGF-TGIHCE-EDVNECS 290
Query: 238 EGGMVCRN-GRCRNTVGSFRCECAPGYTLTA---DGRNCRDV-DECDELPHPCGRDGN-- 290
C+N G C N G++ C C P L+ GR+C D+ C C +G
Sbjct: 291 SN--PCQNGGTCENLPGNYTCHC-PFDNLSRTFYGGRDCSDILLGCTH--QQCLNNGTCI 345
Query: 291 PSCTNTNGGYECSCGAGW 308
P + G+ C C +G+
Sbjct: 346 PHFQDGQHGFSCLCPSGY 363
Score = 72.9 bits (171), Expect = 4e-12
Identities = 65/240 (27%), Positives = 95/240 (39%), Gaps = 28/240 (11%)
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDG 463
P +F++I + L L+ C P C+ GG C + S+ C CP G+ G
Sbjct: 1008 PQEEQFLKISTNSVVTGCL--QLNVCNSNP--CLHGGNCEDIYSSYHCSCPLGW----SG 1059
Query: 464 LSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRASCT 521
C ++ DEC +P C +G CS+ Y C C PG+T C VD+D C + +
Sbjct: 1060 KHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEPGYT---GVNCEVDIDNCQSHQCANG 1114
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + + C C + G CR + VC + N+ C E
Sbjct: 1115 ATCISHTNGYSCLCFGNFT----GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1167
Query: 582 RTSA---PQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
P + CE DI+EC + +GG+C + F C CD F D D
Sbjct: 1168 ELKCMCRPGFTGEWCEKDIDEC-ASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1226
Score = 67.7 bits (158), Expect = 2e-10
Identities = 64/231 (27%), Positives = 92/231 (39%), Gaps = 43/231 (18%)
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG 330
C ++ C+ +PC GN C + Y CSC GW G+ C ++ DEC P C
Sbjct: 1025 CLQLNVCNS--NPCLHGGN--CEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIH 1076
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC-HRARPLQLARPECCC 389
G C + Y C C G+ T C E+ D ++ +C + A + C
Sbjct: 1077 GNCSDRVAAYHCTCEPGY----TGVNC-----EVDIDNCQSHQCANGATCISHTNGYSCL 1127
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
G G++C + P + +C G + NLT C GG C
Sbjct: 1128 CFGNFTGKFCRQSRLPST-----VC--GNEKTNLT-----C------YNGGNCTEFQTEL 1169
Query: 450 RCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGF 499
+C C G+ G C D DECA DP + G G C + ++C C F
Sbjct: 1170 KCMCRPGFT----GEWCEKDIDECASDPCVNG-GLCQDLLNKFQCLCDVAF 1215
Score = 67.7 bits (158), Expect = 2e-10
Identities = 45/159 (28%), Positives = 66/159 (41%), Gaps = 13/159 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P C G C D + C C+ GY N D+D C C A C+
Sbjct: 1066 IDECFSNP--CIHGNCSDRVAAYHCTCEPGYTGVNCE---VDIDNCQ--SHQCANGATCI 1118
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQR---IC-DHGDCRNTIGSYRCECKPGYT 183
+ + C C + CG+++ C + G+C +C C+PG+T
Sbjct: 1119 SHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1178
Query: 184 LRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
E +D+DEC+ P G C++L + C CD F
Sbjct: 1179 -GEWCEKDIDECASD-PCVNGGLCQDLLNKFQCLCDVAF 1215
Score = 66.9 bits (156), Expect = 3e-10
Identities = 62/234 (26%), Positives = 90/234 (38%), Gaps = 35/234 (14%)
Query: 59 NPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRP 118
N V ++ C+ P L G C D + + C C G+ + H ++DEC + P
Sbjct: 1019 NSVVTGCLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGW---SGKHCELNIDEC-FSNP 1073
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCE 177
G C + A+ C C PGY CE D+D C + + C + Y C
Sbjct: 1074 CIHG--NCSDRVAAYHCTCEPGYTGV----NCEVDIDNCQSHQCANGATCISHTNGYSCL 1127
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRN----------GTCENLPGAYLCHCDDGFKAGPN 227
C +T CR + P VC N G C C C GF G
Sbjct: 1128 CFGNFT--GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF-TGEW 1181
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDEL 281
+ D++EC V G C++ + F+C C + G C +VD D+L
Sbjct: 1182 CE-KDIDECASDPCV-NGGLCQDLLNKFQCLCDVAFA----GERC-EVDLADDL 1228
Score = 54.8 bits (126), Expect = 1e-06
Identities = 43/113 (38%), Positives = 55/113 (48%), Gaps = 17/113 (15%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D DECA+ P +C G + C C PGY+ G C +VDECA P + C N
Sbjct: 148 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQ--GRHCDLEVDECASDPCKNEATCLNEI 205
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G Y C+C Y GA C D++EC +++ CQ SN E E S E Y
Sbjct: 206 GRYTCICPHNYS-GYTGAQCEIDLNEC--NSNPCQ---SNGE-CVELSSEKQY 251
Score = 48.8 bits (111), Expect = 8e-05
Identities = 50/175 (28%), Positives = 67/175 (38%), Gaps = 31/175 (17%)
Query: 68 IDECDIMPQLCK-PGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
+DEC P CK TC + + C C H Y + D++EC+ PC+ +C
Sbjct: 187 VDECASDP--CKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNECNSN--PCQSNGEC 242
Query: 127 VNL------------PGAFE--------CRCPPGYRLTPSLDECEDVDECGDQRICDHGD 166
V L P +F C C PG+ + EDV+EC + G
Sbjct: 243 VELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFT---GIHCEEDVNECSSNPCQNGGT 299
Query: 167 CRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDG 221
C N G+Y C C P L D CS C + C N G + H DG
Sbjct: 300 CENLPGNYTCHC-PFDNLSRTFYGGRD-CSDILLGCTHQQCLN-NGTCIPHFQDG 351
Score = 45.2 bits (102), Expect = 0.001
Identities = 28/94 (29%), Positives = 36/94 (38%), Gaps = 8/94 (8%)
Query: 763 FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F C C PGY +G +C + C +CH C+C GY G C
Sbjct: 94 FLCKCPPGY--SGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYA----GRFCEI 147
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
D DEC +C + Y C C GY+ R
Sbjct: 148 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGR 181
Score = 39.9 bits (89), Expect = 0.038
Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 20/100 (20%)
Query: 765 CVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLC------RTGYELDEDGA 817
C+C PG+ G C DV+EC+ P C N G+Y C C RT Y G
Sbjct: 271 CICQPGF--TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFY----GGR 324
Query: 818 NCRDV------DECERDTHTCQQICSNTEGSYECSCEDGY 851
+C D+ +C + TC + + + C C GY
Sbjct: 325 DCSDILLGCTHQQC-LNNGTCIPHFQDGQHGFSCLCPSGY 363
Score = 39.1 bits (87), Expect = 0.066
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
Query: 764 RCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
+C+C PG+ GE C D+DECA P LC + + CLC +
Sbjct: 1170 KCMCRPGF--TGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1215
Score = 38.7 bits (86), Expect = 0.087
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 6/75 (8%)
Query: 778 CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQIC 836
C ++ C P C + SY C C G+ G +C ++DEC + C
Sbjct: 1025 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWS----GKHCELNIDECFSNP-CIHGNC 1079
Query: 837 SNTEGSYECSCEDGY 851
S+ +Y C+CE GY
Sbjct: 1080 SDRVAAYHCTCEPGY 1094
Score = 37.1 bits (82), Expect = 0.27
Identities = 32/119 (26%), Positives = 45/119 (37%), Gaps = 20/119 (16%)
Query: 747 DVDECAAIP---GLCAP--GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDG 800
++DEC + P G C+ + C C PGY G C D+D C C +
Sbjct: 1065 NIDECFSNPCIHGNCSDRVAAYHCTCEPGY--TGVNCEVDIDNCQSHQCANGATCISHTN 1122
Query: 801 SYDCLCRTGYELDEDGANCRD------VDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
Y CLC + G CR V E+ TC C+ + +C C G+
Sbjct: 1123 GYSCLCFGNF----TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF 1177
Score = 33.1 bits (72), Expect = 4.3
Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 795 CHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C C+CR G+ G C +D+DEC D +C + ++C C+ +
Sbjct: 1162 CTEFQTELKCMCRPGFT----GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF-- 1215
Query: 854 RGDAC 858
G+ C
Sbjct: 1216 AGERC 1220
Score = 32.7 bits (71), Expect = 5.7
Identities = 19/72 (26%), Positives = 27/72 (37%), Gaps = 8/72 (11%)
Query: 505 QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA 564
Q C + C CH+ F C+CP G C ++ C P CPH
Sbjct: 771 QGCAGDNSCKSNPCHNGGVCHSRWDDFSCSCP----ALTSGKACEEVQWCGFSP--CPHG 824
Query: 565 --CENVVGSYIC 574
C+ V+ + C
Sbjct: 825 AQCQPVLQGFEC 836
>AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1294
Score = 105 bits (253), Expect = 5e-22
Identities = 98/292 (33%), Positives = 128/292 (43%), Gaps = 51/292 (17%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS--WGRPPCRGMAQCVNLPG--AFECRC 137
TC D C C D ++L +D D PC+G A CVN PG +F C+C
Sbjct: 44 TCKDFSKDNDCSCS-----DTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKC 98
Query: 138 PPGYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYR-CECKPGYTLRENVCR-DVDE 194
PPGY T CE + CG + C HG + Y C C GY R C D DE
Sbjct: 99 PPGYSGTI----CETTIGSCG-KNSCQHGGICHQDPIYPVCICPAGYAGR--FCEIDHDE 151
Query: 195 CSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTV 252
C+ C+NG C++ Y C C G++ G + D ++V+EC C+N C N +
Sbjct: 152 CASSP--CQNGAVCQDGIDGYSCFCVPGYQ-GRHCD-LEVDECASDP--CKNEATCLNEI 205
Query: 253 GSFRCECAPGYTLTADGRNCR-DVDECDELP----HPC---------GR-DGNPSCTNTN 297
G + C C Y+ G C D++EC+ P C GR G PS + +
Sbjct: 206 GRYTCICPHNYS-GYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYH 264
Query: 298 --GGYECSCGAGWKLVGRRCV-DRDECKELPYVCA-GGECRNFNGGYVCECP 345
GY C C G+ G C D +EC P C GG C N G Y C CP
Sbjct: 265 EASGYVCICQPGF--TGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHCP 312
Score = 88.6 bits (210), Expect = 8e-17
Identities = 94/357 (26%), Positives = 137/357 (38%), Gaps = 52/357 (14%)
Query: 163 DHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPG--AYLCHCDD 220
++ C++ C C + C ++ + P + TC N PG ++LC C
Sbjct: 41 NNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPP 100
Query: 221 GFKAGPNNDCV---DVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVD 276
G+ + N C+ GG +C C C GY GR C D D
Sbjct: 101 GYSGTICETTIGSCGKNSCQHGG-ICHQDPIYPV-----CICPAGYA----GRFCEIDHD 150
Query: 277 ECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECR 334
EC PC C + GY C C G++ GR C ++ DEC P C C
Sbjct: 151 EC--ASSPC--QNGAVCQDGIDGYSCFCVPGYQ--GRHCDLEVDECASDP--CKNEATCL 202
Query: 335 NFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECC-CSEGA 393
N G Y C CP + T A C E + C+ + P Q + EC S
Sbjct: 203 NEIGRYTCICPHNYS-GYTGAQC----------EIDLNECN-SNPCQ-SNGECVELSSEK 249
Query: 394 AWGRYC---ERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSF 449
+GR +++ ++ ICQ G + +D++EC P C GG C N G++
Sbjct: 250 QYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNY 307
Query: 450 RCECPDGYVLAP--DGLSCVDADECALDPRICGNGTC----SNTRGGYECQCSPGFT 500
C CP + G C D + NGTC + + G+ C C G+T
Sbjct: 308 TCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYT 364
Score = 88.6 bits (210), Expect = 8e-17
Identities = 64/216 (29%), Positives = 93/216 (43%), Gaps = 27/216 (12%)
Query: 107 CRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG 165
C ++ C+ PC C ++ ++ C CP G+ S CE ++DEC C HG
Sbjct: 1025 CLQLNVCNSN--PCLHGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECFSNP-CIHG 1077
Query: 166 DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKA 224
+C + + +Y C C+PGYT N D+D C + C NG TC + Y C C F
Sbjct: 1078 NCSDRVAAYHCTCEPGYT-GVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLCFGNFTG 1134
Query: 225 G-PNNDCVDVNEC--REGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECD 279
+ C + + C N G C +C C PG+T G C +D+DEC
Sbjct: 1135 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT----GEWCEKDIDEC- 1189
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
PC G C + ++C C + G RC
Sbjct: 1190 -ASDPCVNGG--LCQDLLNKFQCLCDVAF--AGERC 1220
Score = 80.2 bits (189), Expect = 3e-14
Identities = 103/375 (27%), Positives = 142/375 (37%), Gaps = 85/375 (22%)
Query: 290 NPSCTNTNGGYECSCGAGWKLVGRRCVD-RDECKELPYVCAGGE-CRNFNG--GYVCECP 345
N +C + + +CSC + + C + +D C P C G C N G ++C+CP
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNP--CQGSATCVNTPGERSFLCKCP 99
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
G+ K C G CH+ P+ P C C G A
Sbjct: 100 PGYSGTICETTIGSCGKNSCQ---HGGICHQD-PIY---PVCICPAGYAG---------- 142
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGL 464
R C+ D DEC P C G C + + C C GY G
Sbjct: 143 ------RFCE---------IDHDECASSP--CQNGAVCQDGIDGYSCFCVPGY----QGR 181
Query: 465 SC-VDADECALDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTC-VDVDEC----AEGR 517
C ++ DECA DP C N TC N G Y C C ++ C +D++EC +
Sbjct: 182 HCDLEVDECASDP--CKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSN 239
Query: 518 ASC-----------------TFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPR 559
C +F H +G + C C G+ G+HC D++EC P
Sbjct: 240 GECVELSSEKQYGRITGLPSSFSYHEASG-YVCICQPGFT----GIHCEEDVNECSSNPC 294
Query: 560 VCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDI-NECEEQEDLCSGGVCIN--TDG 616
CEN+ G+Y C CP + S C DI C Q+ L + G CI DG
Sbjct: 295 QNGGTCENLPGNYTCHCP--FDNLSRTFYGGRDCSDILLGCTHQQCL-NNGTCIPHFQDG 351
Query: 617 --SFLCDCDAGFEPS 629
F C C +G+ S
Sbjct: 352 QHGFSCLCPSGYTGS 366
Score = 80.2 bits (189), Expect = 3e-14
Identities = 79/258 (30%), Positives = 104/258 (40%), Gaps = 47/258 (18%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
G CH P C C GY C D DEC+ PC+ A C + + C C P
Sbjct: 123 GICHQDPIYPVCICPAGY----AGRFCEIDHDECA--SSPCQNGAVCQDGIDGYSCFCVP 176
Query: 140 GYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECK---PGYT-------LRE-- 186
GY+ C+ +VDEC + C N IG Y C C GYT L E
Sbjct: 177 GYQGR----HCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNECN 232
Query: 187 -NVCRDVDECSRPRPVCRNGTCENLPGA--------YLCHCDDGFKAGPNNDCVDVNECR 237
N C+ EC + G LP + Y+C C GF G + + DVNEC
Sbjct: 233 SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGF-TGIHCE-EDVNECS 290
Query: 238 EGGMVCRN-GRCRNTVGSFRCECAPGYTLTA---DGRNCRDV-DECDELPHPCGRDGN-- 290
C+N G C N G++ C C P L+ GR+C D+ C C +G
Sbjct: 291 SN--PCQNGGTCENLPGNYTCHC-PFDNLSRTFYGGRDCSDILLGCTH--QQCLNNGTCI 345
Query: 291 PSCTNTNGGYECSCGAGW 308
P + G+ C C +G+
Sbjct: 346 PHFQDGQHGFSCLCPSGY 363
Score = 72.9 bits (171), Expect = 4e-12
Identities = 65/240 (27%), Positives = 95/240 (39%), Gaps = 28/240 (11%)
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDG 463
P +F++I + L L+ C P C+ GG C + S+ C CP G+ G
Sbjct: 1008 PQEEQFLKISTNSVVTGCL--QLNVCNSNP--CLHGGNCEDIYSSYHCSCPLGW----SG 1059
Query: 464 LSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRASCT 521
C ++ DEC +P C +G CS+ Y C C PG+T C VD+D C + +
Sbjct: 1060 KHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEPGYT---GVNCEVDIDNCQSHQCANG 1114
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + + C C + G CR + VC + N+ C E
Sbjct: 1115 ATCISHTNGYSCLCFGNFT----GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1167
Query: 582 RTSA---PQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
P + CE DI+EC + +GG+C + F C CD F D D
Sbjct: 1168 ELKCMCRPGFTGEWCEKDIDEC-ASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1226
Score = 67.7 bits (158), Expect = 2e-10
Identities = 64/231 (27%), Positives = 92/231 (39%), Gaps = 43/231 (18%)
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG 330
C ++ C+ +PC GN C + Y CSC GW G+ C ++ DEC P C
Sbjct: 1025 CLQLNVCNS--NPCLHGGN--CEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIH 1076
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC-HRARPLQLARPECCC 389
G C + Y C C G+ T C E+ D ++ +C + A + C
Sbjct: 1077 GNCSDRVAAYHCTCEPGY----TGVNC-----EVDIDNCQSHQCANGATCISHTNGYSCL 1127
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
G G++C + P + +C G + NLT C GG C
Sbjct: 1128 CFGNFTGKFCRQSRLPST-----VC--GNEKTNLT-----C------YNGGNCTEFQTEL 1169
Query: 450 RCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGF 499
+C C G+ G C D DECA DP + G G C + ++C C F
Sbjct: 1170 KCMCRPGFT----GEWCEKDIDECASDPCVNG-GLCQDLLNKFQCLCDVAF 1215
Score = 67.7 bits (158), Expect = 2e-10
Identities = 45/159 (28%), Positives = 66/159 (41%), Gaps = 13/159 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P C G C D + C C+ GY N D+D C C A C+
Sbjct: 1066 IDECFSNP--CIHGNCSDRVAAYHCTCEPGYTGVNCE---VDIDNCQ--SHQCANGATCI 1118
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQR---IC-DHGDCRNTIGSYRCECKPGYT 183
+ + C C + CG+++ C + G+C +C C+PG+T
Sbjct: 1119 SHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1178
Query: 184 LRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
E +D+DEC+ P G C++L + C CD F
Sbjct: 1179 -GEWCEKDIDECASD-PCVNGGLCQDLLNKFQCLCDVAF 1215
Score = 66.9 bits (156), Expect = 3e-10
Identities = 62/234 (26%), Positives = 90/234 (38%), Gaps = 35/234 (14%)
Query: 59 NPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRP 118
N V ++ C+ P L G C D + + C C G+ + H ++DEC + P
Sbjct: 1019 NSVVTGCLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGW---SGKHCELNIDEC-FSNP 1073
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCE 177
G C + A+ C C PGY CE D+D C + + C + Y C
Sbjct: 1074 CIHG--NCSDRVAAYHCTCEPGYTGV----NCEVDIDNCQSHQCANGATCISHTNGYSCL 1127
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRN----------GTCENLPGAYLCHCDDGFKAGPN 227
C +T CR + P VC N G C C C GF G
Sbjct: 1128 CFGNFT--GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF-TGEW 1181
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDEL 281
+ D++EC V G C++ + F+C C + G C +VD D+L
Sbjct: 1182 CE-KDIDECASDPCV-NGGLCQDLLNKFQCLCDVAFA----GERC-EVDLADDL 1228
Score = 54.8 bits (126), Expect = 1e-06
Identities = 43/113 (38%), Positives = 55/113 (48%), Gaps = 17/113 (15%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D DECA+ P +C G + C C PGY+ G C +VDECA P + C N
Sbjct: 148 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQ--GRHCDLEVDECASDPCKNEATCLNEI 205
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G Y C+C Y GA C D++EC +++ CQ SN E E S E Y
Sbjct: 206 GRYTCICPHNYS-GYTGAQCEIDLNEC--NSNPCQ---SNGE-CVELSSEKQY 251
Score = 48.8 bits (111), Expect = 8e-05
Identities = 50/175 (28%), Positives = 67/175 (38%), Gaps = 31/175 (17%)
Query: 68 IDECDIMPQLCK-PGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
+DEC P CK TC + + C C H Y + D++EC+ PC+ +C
Sbjct: 187 VDECASDP--CKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNECNSN--PCQSNGEC 242
Query: 127 VNL------------PGAFE--------CRCPPGYRLTPSLDECEDVDECGDQRICDHGD 166
V L P +F C C PG+ + EDV+EC + G
Sbjct: 243 VELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFT---GIHCEEDVNECSSNPCQNGGT 299
Query: 167 CRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDG 221
C N G+Y C C P L D CS C + C N G + H DG
Sbjct: 300 CENLPGNYTCHC-PFDNLSRTFYGGRD-CSDILLGCTHQQCLN-NGTCIPHFQDG 351
Score = 45.2 bits (102), Expect = 0.001
Identities = 28/94 (29%), Positives = 36/94 (38%), Gaps = 8/94 (8%)
Query: 763 FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F C C PGY +G +C + C +CH C+C GY G C
Sbjct: 94 FLCKCPPGY--SGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYA----GRFCEI 147
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
D DEC +C + Y C C GY+ R
Sbjct: 148 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGR 181
Score = 39.9 bits (89), Expect = 0.038
Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 20/100 (20%)
Query: 765 CVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLC------RTGYELDEDGA 817
C+C PG+ G C DV+EC+ P C N G+Y C C RT Y G
Sbjct: 271 CICQPGF--TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFY----GGR 324
Query: 818 NCRDV------DECERDTHTCQQICSNTEGSYECSCEDGY 851
+C D+ +C + TC + + + C C GY
Sbjct: 325 DCSDILLGCTHQQC-LNNGTCIPHFQDGQHGFSCLCPSGY 363
Score = 39.1 bits (87), Expect = 0.066
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
Query: 764 RCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
+C+C PG+ GE C D+DECA P LC + + CLC +
Sbjct: 1170 KCMCRPGF--TGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1215
Score = 38.7 bits (86), Expect = 0.087
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 6/75 (8%)
Query: 778 CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQIC 836
C ++ C P C + SY C C G+ G +C ++DEC + C
Sbjct: 1025 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWS----GKHCELNIDECFSNP-CIHGNC 1079
Query: 837 SNTEGSYECSCEDGY 851
S+ +Y C+CE GY
Sbjct: 1080 SDRVAAYHCTCEPGY 1094
Score = 37.1 bits (82), Expect = 0.27
Identities = 32/119 (26%), Positives = 45/119 (37%), Gaps = 20/119 (16%)
Query: 747 DVDECAAIP---GLCAP--GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDG 800
++DEC + P G C+ + C C PGY G C D+D C C +
Sbjct: 1065 NIDECFSNPCIHGNCSDRVAAYHCTCEPGY--TGVNCEVDIDNCQSHQCANGATCISHTN 1122
Query: 801 SYDCLCRTGYELDEDGANCRD------VDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
Y CLC + G CR V E+ TC C+ + +C C G+
Sbjct: 1123 GYSCLCFGNF----TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF 1177
Score = 33.1 bits (72), Expect = 4.3
Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 795 CHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C C+CR G+ G C +D+DEC D +C + ++C C+ +
Sbjct: 1162 CTEFQTELKCMCRPGFT----GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF-- 1215
Query: 854 RGDAC 858
G+ C
Sbjct: 1216 AGERC 1220
Score = 32.7 bits (71), Expect = 5.7
Identities = 19/72 (26%), Positives = 27/72 (37%), Gaps = 8/72 (11%)
Query: 505 QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA 564
Q C + C CH+ F C+CP G C ++ C P CPH
Sbjct: 771 QGCAGDNSCKSNPCHNGGVCHSRWDDFSCSCP----ALTSGKACEEVQWCGFSP--CPHG 824
Query: 565 --CENVVGSYIC 574
C+ V+ + C
Sbjct: 825 AQCQPVLQGFEC 836
>AL136322-3|CAM23328.1| 1294|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1294
Score = 105 bits (253), Expect = 5e-22
Identities = 98/292 (33%), Positives = 128/292 (43%), Gaps = 51/292 (17%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS--WGRPPCRGMAQCVNLPG--AFECRC 137
TC D C C D ++L +D D PC+G A CVN PG +F C+C
Sbjct: 44 TCKDFSKDNDCSCS-----DTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKC 98
Query: 138 PPGYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYR-CECKPGYTLRENVCR-DVDE 194
PPGY T CE + CG + C HG + Y C C GY R C D DE
Sbjct: 99 PPGYSGTI----CETTIGSCG-KNSCQHGGICHQDPIYPVCICPAGYAGR--FCEIDHDE 151
Query: 195 CSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTV 252
C+ C+NG C++ Y C C G++ G + D ++V+EC C+N C N +
Sbjct: 152 CASSP--CQNGAVCQDGIDGYSCFCVPGYQ-GRHCD-LEVDECASDP--CKNEATCLNEI 205
Query: 253 GSFRCECAPGYTLTADGRNCR-DVDECDELP----HPC---------GR-DGNPSCTNTN 297
G + C C Y+ G C D++EC+ P C GR G PS + +
Sbjct: 206 GRYTCICPHNYS-GYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYH 264
Query: 298 --GGYECSCGAGWKLVGRRCV-DRDECKELPYVCA-GGECRNFNGGYVCECP 345
GY C C G+ G C D +EC P C GG C N G Y C CP
Sbjct: 265 EASGYVCICQPGF--TGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHCP 312
Score = 88.6 bits (210), Expect = 8e-17
Identities = 94/357 (26%), Positives = 137/357 (38%), Gaps = 52/357 (14%)
Query: 163 DHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPG--AYLCHCDD 220
++ C++ C C + C ++ + P + TC N PG ++LC C
Sbjct: 41 NNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPP 100
Query: 221 GFKAGPNNDCV---DVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVD 276
G+ + N C+ GG +C C C GY GR C D D
Sbjct: 101 GYSGTICETTIGSCGKNSCQHGG-ICHQDPIYPV-----CICPAGYA----GRFCEIDHD 150
Query: 277 ECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECR 334
EC PC C + GY C C G++ GR C ++ DEC P C C
Sbjct: 151 EC--ASSPC--QNGAVCQDGIDGYSCFCVPGYQ--GRHCDLEVDECASDP--CKNEATCL 202
Query: 335 NFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECC-CSEGA 393
N G Y C CP + T A C E + C+ + P Q + EC S
Sbjct: 203 NEIGRYTCICPHNYS-GYTGAQC----------EIDLNECN-SNPCQ-SNGECVELSSEK 249
Query: 394 AWGRYC---ERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSF 449
+GR +++ ++ ICQ G + +D++EC P C GG C N G++
Sbjct: 250 QYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNY 307
Query: 450 RCECPDGYVLAP--DGLSCVDADECALDPRICGNGTC----SNTRGGYECQCSPGFT 500
C CP + G C D + NGTC + + G+ C C G+T
Sbjct: 308 TCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYT 364
Score = 88.6 bits (210), Expect = 8e-17
Identities = 64/216 (29%), Positives = 93/216 (43%), Gaps = 27/216 (12%)
Query: 107 CRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG 165
C ++ C+ PC C ++ ++ C CP G+ S CE ++DEC C HG
Sbjct: 1025 CLQLNVCNSN--PCLHGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECFSNP-CIHG 1077
Query: 166 DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKA 224
+C + + +Y C C+PGYT N D+D C + C NG TC + Y C C F
Sbjct: 1078 NCSDRVAAYHCTCEPGYT-GVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLCFGNFTG 1134
Query: 225 G-PNNDCVDVNEC--REGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECD 279
+ C + + C N G C +C C PG+T G C +D+DEC
Sbjct: 1135 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT----GEWCEKDIDEC- 1189
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
PC G C + ++C C + G RC
Sbjct: 1190 -ASDPCVNGG--LCQDLLNKFQCLCDVAF--AGERC 1220
Score = 80.2 bits (189), Expect = 3e-14
Identities = 103/375 (27%), Positives = 142/375 (37%), Gaps = 85/375 (22%)
Query: 290 NPSCTNTNGGYECSCGAGWKLVGRRCVD-RDECKELPYVCAGGE-CRNFNG--GYVCECP 345
N +C + + +CSC + + C + +D C P C G C N G ++C+CP
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNP--CQGSATCVNTPGERSFLCKCP 99
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
G+ K C G CH+ P+ P C C G A
Sbjct: 100 PGYSGTICETTIGSCGKNSCQ---HGGICHQD-PIY---PVCICPAGYAG---------- 142
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGL 464
R C+ D DEC P C G C + + C C GY G
Sbjct: 143 ------RFCE---------IDHDECASSP--CQNGAVCQDGIDGYSCFCVPGY----QGR 181
Query: 465 SC-VDADECALDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTC-VDVDEC----AEGR 517
C ++ DECA DP C N TC N G Y C C ++ C +D++EC +
Sbjct: 182 HCDLEVDECASDP--CKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSN 239
Query: 518 ASC-----------------TFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPR 559
C +F H +G + C C G+ G+HC D++EC P
Sbjct: 240 GECVELSSEKQYGRITGLPSSFSYHEASG-YVCICQPGFT----GIHCEEDVNECSSNPC 294
Query: 560 VCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDI-NECEEQEDLCSGGVCIN--TDG 616
CEN+ G+Y C CP + S C DI C Q+ L + G CI DG
Sbjct: 295 QNGGTCENLPGNYTCHCP--FDNLSRTFYGGRDCSDILLGCTHQQCL-NNGTCIPHFQDG 351
Query: 617 --SFLCDCDAGFEPS 629
F C C +G+ S
Sbjct: 352 QHGFSCLCPSGYTGS 366
Score = 80.2 bits (189), Expect = 3e-14
Identities = 79/258 (30%), Positives = 104/258 (40%), Gaps = 47/258 (18%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
G CH P C C GY C D DEC+ PC+ A C + + C C P
Sbjct: 123 GICHQDPIYPVCICPAGY----AGRFCEIDHDECA--SSPCQNGAVCQDGIDGYSCFCVP 176
Query: 140 GYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECK---PGYT-------LRE-- 186
GY+ C+ +VDEC + C N IG Y C C GYT L E
Sbjct: 177 GYQGR----HCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNECN 232
Query: 187 -NVCRDVDECSRPRPVCRNGTCENLPGA--------YLCHCDDGFKAGPNNDCVDVNECR 237
N C+ EC + G LP + Y+C C GF G + + DVNEC
Sbjct: 233 SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGF-TGIHCE-EDVNECS 290
Query: 238 EGGMVCRN-GRCRNTVGSFRCECAPGYTLTA---DGRNCRDV-DECDELPHPCGRDGN-- 290
C+N G C N G++ C C P L+ GR+C D+ C C +G
Sbjct: 291 SN--PCQNGGTCENLPGNYTCHC-PFDNLSRTFYGGRDCSDILLGCTH--QQCLNNGTCI 345
Query: 291 PSCTNTNGGYECSCGAGW 308
P + G+ C C +G+
Sbjct: 346 PHFQDGQHGFSCLCPSGY 363
Score = 72.9 bits (171), Expect = 4e-12
Identities = 65/240 (27%), Positives = 95/240 (39%), Gaps = 28/240 (11%)
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDG 463
P +F++I + L L+ C P C+ GG C + S+ C CP G+ G
Sbjct: 1008 PQEEQFLKISTNSVVTGCL--QLNVCNSNP--CLHGGNCEDIYSSYHCSCPLGW----SG 1059
Query: 464 LSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRASCT 521
C ++ DEC +P C +G CS+ Y C C PG+T C VD+D C + +
Sbjct: 1060 KHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEPGYT---GVNCEVDIDNCQSHQCANG 1114
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + + C C + G CR + VC + N+ C E
Sbjct: 1115 ATCISHTNGYSCLCFGNFT----GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1167
Query: 582 RTSA---PQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
P + CE DI+EC + +GG+C + F C CD F D D
Sbjct: 1168 ELKCMCRPGFTGEWCEKDIDEC-ASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1226
Score = 67.7 bits (158), Expect = 2e-10
Identities = 64/231 (27%), Positives = 92/231 (39%), Gaps = 43/231 (18%)
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG 330
C ++ C+ +PC GN C + Y CSC GW G+ C ++ DEC P C
Sbjct: 1025 CLQLNVCNS--NPCLHGGN--CEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIH 1076
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC-HRARPLQLARPECCC 389
G C + Y C C G+ T C E+ D ++ +C + A + C
Sbjct: 1077 GNCSDRVAAYHCTCEPGY----TGVNC-----EVDIDNCQSHQCANGATCISHTNGYSCL 1127
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
G G++C + P + +C G + NLT C GG C
Sbjct: 1128 CFGNFTGKFCRQSRLPST-----VC--GNEKTNLT-----C------YNGGNCTEFQTEL 1169
Query: 450 RCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGF 499
+C C G+ G C D DECA DP + G G C + ++C C F
Sbjct: 1170 KCMCRPGFT----GEWCEKDIDECASDPCVNG-GLCQDLLNKFQCLCDVAF 1215
Score = 67.7 bits (158), Expect = 2e-10
Identities = 45/159 (28%), Positives = 66/159 (41%), Gaps = 13/159 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P C G C D + C C+ GY N D+D C C A C+
Sbjct: 1066 IDECFSNP--CIHGNCSDRVAAYHCTCEPGYTGVNCE---VDIDNCQ--SHQCANGATCI 1118
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQR---IC-DHGDCRNTIGSYRCECKPGYT 183
+ + C C + CG+++ C + G+C +C C+PG+T
Sbjct: 1119 SHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1178
Query: 184 LRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
E +D+DEC+ P G C++L + C CD F
Sbjct: 1179 -GEWCEKDIDECASD-PCVNGGLCQDLLNKFQCLCDVAF 1215
Score = 66.9 bits (156), Expect = 3e-10
Identities = 62/234 (26%), Positives = 90/234 (38%), Gaps = 35/234 (14%)
Query: 59 NPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRP 118
N V ++ C+ P L G C D + + C C G+ + H ++DEC + P
Sbjct: 1019 NSVVTGCLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGW---SGKHCELNIDEC-FSNP 1073
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCE 177
G C + A+ C C PGY CE D+D C + + C + Y C
Sbjct: 1074 CIHG--NCSDRVAAYHCTCEPGYTGV----NCEVDIDNCQSHQCANGATCISHTNGYSCL 1127
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRN----------GTCENLPGAYLCHCDDGFKAGPN 227
C +T CR + P VC N G C C C GF G
Sbjct: 1128 CFGNFT--GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF-TGEW 1181
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDEL 281
+ D++EC V G C++ + F+C C + G C +VD D+L
Sbjct: 1182 CE-KDIDECASDPCV-NGGLCQDLLNKFQCLCDVAFA----GERC-EVDLADDL 1228
Score = 54.8 bits (126), Expect = 1e-06
Identities = 43/113 (38%), Positives = 55/113 (48%), Gaps = 17/113 (15%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D DECA+ P +C G + C C PGY+ G C +VDECA P + C N
Sbjct: 148 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQ--GRHCDLEVDECASDPCKNEATCLNEI 205
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G Y C+C Y GA C D++EC +++ CQ SN E E S E Y
Sbjct: 206 GRYTCICPHNYS-GYTGAQCEIDLNEC--NSNPCQ---SNGE-CVELSSEKQY 251
Score = 48.8 bits (111), Expect = 8e-05
Identities = 50/175 (28%), Positives = 67/175 (38%), Gaps = 31/175 (17%)
Query: 68 IDECDIMPQLCK-PGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
+DEC P CK TC + + C C H Y + D++EC+ PC+ +C
Sbjct: 187 VDECASDP--CKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNECNSN--PCQSNGEC 242
Query: 127 VNL------------PGAFE--------CRCPPGYRLTPSLDECEDVDECGDQRICDHGD 166
V L P +F C C PG+ + EDV+EC + G
Sbjct: 243 VELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFT---GIHCEEDVNECSSNPCQNGGT 299
Query: 167 CRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDG 221
C N G+Y C C P L D CS C + C N G + H DG
Sbjct: 300 CENLPGNYTCHC-PFDNLSRTFYGGRD-CSDILLGCTHQQCLN-NGTCIPHFQDG 351
Score = 45.2 bits (102), Expect = 0.001
Identities = 28/94 (29%), Positives = 36/94 (38%), Gaps = 8/94 (8%)
Query: 763 FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F C C PGY +G +C + C +CH C+C GY G C
Sbjct: 94 FLCKCPPGY--SGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYA----GRFCEI 147
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
D DEC +C + Y C C GY+ R
Sbjct: 148 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGR 181
Score = 39.9 bits (89), Expect = 0.038
Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 20/100 (20%)
Query: 765 CVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLC------RTGYELDEDGA 817
C+C PG+ G C DV+EC+ P C N G+Y C C RT Y G
Sbjct: 271 CICQPGF--TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFY----GGR 324
Query: 818 NCRDV------DECERDTHTCQQICSNTEGSYECSCEDGY 851
+C D+ +C + TC + + + C C GY
Sbjct: 325 DCSDILLGCTHQQC-LNNGTCIPHFQDGQHGFSCLCPSGY 363
Score = 39.1 bits (87), Expect = 0.066
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
Query: 764 RCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
+C+C PG+ GE C D+DECA P LC + + CLC +
Sbjct: 1170 KCMCRPGF--TGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1215
Score = 38.7 bits (86), Expect = 0.087
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 6/75 (8%)
Query: 778 CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQIC 836
C ++ C P C + SY C C G+ G +C ++DEC + C
Sbjct: 1025 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWS----GKHCELNIDECFSNP-CIHGNC 1079
Query: 837 SNTEGSYECSCEDGY 851
S+ +Y C+CE GY
Sbjct: 1080 SDRVAAYHCTCEPGY 1094
Score = 37.1 bits (82), Expect = 0.27
Identities = 32/119 (26%), Positives = 45/119 (37%), Gaps = 20/119 (16%)
Query: 747 DVDECAAIP---GLCAP--GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDG 800
++DEC + P G C+ + C C PGY G C D+D C C +
Sbjct: 1065 NIDECFSNPCIHGNCSDRVAAYHCTCEPGY--TGVNCEVDIDNCQSHQCANGATCISHTN 1122
Query: 801 SYDCLCRTGYELDEDGANCRD------VDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
Y CLC + G CR V E+ TC C+ + +C C G+
Sbjct: 1123 GYSCLCFGNF----TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF 1177
Score = 33.1 bits (72), Expect = 4.3
Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 795 CHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C C+CR G+ G C +D+DEC D +C + ++C C+ +
Sbjct: 1162 CTEFQTELKCMCRPGFT----GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF-- 1215
Query: 854 RGDAC 858
G+ C
Sbjct: 1216 AGERC 1220
Score = 32.7 bits (71), Expect = 5.7
Identities = 19/72 (26%), Positives = 27/72 (37%), Gaps = 8/72 (11%)
Query: 505 QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA 564
Q C + C CH+ F C+CP G C ++ C P CPH
Sbjct: 771 QGCAGDNSCKSNPCHNGGVCHSRWDDFSCSCP----ALTSGKACEEVQWCGFSP--CPHG 824
Query: 565 --CENVVGSYIC 574
C+ V+ + C
Sbjct: 825 AQCQPVLQGFEC 836
>AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1
(alternative protein) protein.
Length = 1294
Score = 105 bits (253), Expect = 5e-22
Identities = 98/292 (33%), Positives = 128/292 (43%), Gaps = 51/292 (17%)
Query: 82 TCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECS--WGRPPCRGMAQCVNLPG--AFECRC 137
TC D C C D ++L +D D PC+G A CVN PG +F C+C
Sbjct: 44 TCKDFSKDNDCSCS-----DTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKC 98
Query: 138 PPGYRLTPSLDECED-VDECGDQRICDHGDCRNTIGSYR-CECKPGYTLRENVCR-DVDE 194
PPGY T CE + CG + C HG + Y C C GY R C D DE
Sbjct: 99 PPGYSGTI----CETTIGSCG-KNSCQHGGICHQDPIYPVCICPAGYAGR--FCEIDHDE 151
Query: 195 CSRPRPVCRNGT-CENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN-GRCRNTV 252
C+ C+NG C++ Y C C G++ G + D ++V+EC C+N C N +
Sbjct: 152 CASSP--CQNGAVCQDGIDGYSCFCVPGYQ-GRHCD-LEVDECASDP--CKNEATCLNEI 205
Query: 253 GSFRCECAPGYTLTADGRNCR-DVDECDELP----HPC---------GR-DGNPSCTNTN 297
G + C C Y+ G C D++EC+ P C GR G PS + +
Sbjct: 206 GRYTCICPHNYS-GYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYH 264
Query: 298 --GGYECSCGAGWKLVGRRCV-DRDECKELPYVCA-GGECRNFNGGYVCECP 345
GY C C G+ G C D +EC P C GG C N G Y C CP
Sbjct: 265 EASGYVCICQPGF--TGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHCP 312
Score = 88.6 bits (210), Expect = 8e-17
Identities = 94/357 (26%), Positives = 137/357 (38%), Gaps = 52/357 (14%)
Query: 163 DHGDCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPG--AYLCHCDD 220
++ C++ C C + C ++ + P + TC N PG ++LC C
Sbjct: 41 NNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPP 100
Query: 221 GFKAGPNNDCV---DVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCR-DVD 276
G+ + N C+ GG +C C C GY GR C D D
Sbjct: 101 GYSGTICETTIGSCGKNSCQHGG-ICHQDPIYPV-----CICPAGYA----GRFCEIDHD 150
Query: 277 ECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG-GECR 334
EC PC C + GY C C G++ GR C ++ DEC P C C
Sbjct: 151 EC--ASSPC--QNGAVCQDGIDGYSCFCVPGYQ--GRHCDLEVDECASDP--CKNEATCL 202
Query: 335 NFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECC-CSEGA 393
N G Y C CP + T A C E + C+ + P Q + EC S
Sbjct: 203 NEIGRYTCICPHNYS-GYTGAQC----------EIDLNECN-SNPCQ-SNGECVELSSEK 249
Query: 394 AWGRYC---ERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSF 449
+GR +++ ++ ICQ G + +D++EC P C GG C N G++
Sbjct: 250 QYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNY 307
Query: 450 RCECPDGYVLAP--DGLSCVDADECALDPRICGNGTC----SNTRGGYECQCSPGFT 500
C CP + G C D + NGTC + + G+ C C G+T
Sbjct: 308 TCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYT 364
Score = 88.6 bits (210), Expect = 8e-17
Identities = 64/216 (29%), Positives = 93/216 (43%), Gaps = 27/216 (12%)
Query: 107 CRDVDECSWGRPPCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHG 165
C ++ C+ PC C ++ ++ C CP G+ S CE ++DEC C HG
Sbjct: 1025 CLQLNVCNSN--PCLHGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECFSNP-CIHG 1077
Query: 166 DCRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNG-TCENLPGAYLCHCDDGFKA 224
+C + + +Y C C+PGYT N D+D C + C NG TC + Y C C F
Sbjct: 1078 NCSDRVAAYHCTCEPGYT-GVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLCFGNFTG 1134
Query: 225 G-PNNDCVDVNEC--REGGMVCRN-GRCRNTVGSFRCECAPGYTLTADGRNC-RDVDECD 279
+ C + + C N G C +C C PG+T G C +D+DEC
Sbjct: 1135 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT----GEWCEKDIDEC- 1189
Query: 280 ELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC 315
PC G C + ++C C + G RC
Sbjct: 1190 -ASDPCVNGG--LCQDLLNKFQCLCDVAF--AGERC 1220
Score = 80.2 bits (189), Expect = 3e-14
Identities = 103/375 (27%), Positives = 142/375 (37%), Gaps = 85/375 (22%)
Query: 290 NPSCTNTNGGYECSCGAGWKLVGRRCVD-RDECKELPYVCAGGE-CRNFNG--GYVCECP 345
N +C + + +CSC + + C + +D C P C G C N G ++C+CP
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNP--CQGSATCVNTPGERSFLCKCP 99
Query: 346 AGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCCSEGAAWGRYCERCPAP 405
G+ K C G CH+ P+ P C C G A
Sbjct: 100 PGYSGTICETTIGSCGKNSCQ---HGGICHQD-PIY---PVCICPAGYAG---------- 142
Query: 406 DSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGL 464
R C+ D DEC P C G C + + C C GY G
Sbjct: 143 ------RFCE---------IDHDECASSP--CQNGAVCQDGIDGYSCFCVPGY----QGR 181
Query: 465 SC-VDADECALDPRICGN-GTCSNTRGGYECQCSPGFTQGPDQTC-VDVDEC----AEGR 517
C ++ DECA DP C N TC N G Y C C ++ C +D++EC +
Sbjct: 182 HCDLEVDECASDP--CKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSN 239
Query: 518 ASC-----------------TFRCHNTAGSFRCTCPYGYAVAADGVHCR-DIDECVQEPR 559
C +F H +G + C C G+ G+HC D++EC P
Sbjct: 240 GECVELSSEKQYGRITGLPSSFSYHEASG-YVCICQPGFT----GIHCEEDVNECSSNPC 294
Query: 560 VCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDI-NECEEQEDLCSGGVCIN--TDG 616
CEN+ G+Y C CP + S C DI C Q+ L + G CI DG
Sbjct: 295 QNGGTCENLPGNYTCHCP--FDNLSRTFYGGRDCSDILLGCTHQQCL-NNGTCIPHFQDG 351
Query: 617 --SFLCDCDAGFEPS 629
F C C +G+ S
Sbjct: 352 QHGFSCLCPSGYTGS 366
Score = 80.2 bits (189), Expect = 3e-14
Identities = 79/258 (30%), Positives = 104/258 (40%), Gaps = 47/258 (18%)
Query: 81 GTCHDTPTGFQCGCDHGYEHDNTSHLCR-DVDECSWGRPPCRGMAQCVNLPGAFECRCPP 139
G CH P C C GY C D DEC+ PC+ A C + + C C P
Sbjct: 123 GICHQDPIYPVCICPAGY----AGRFCEIDHDECA--SSPCQNGAVCQDGIDGYSCFCVP 176
Query: 140 GYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCECK---PGYT-------LRE-- 186
GY+ C+ +VDEC + C N IG Y C C GYT L E
Sbjct: 177 GYQGR----HCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNECN 232
Query: 187 -NVCRDVDECSRPRPVCRNGTCENLPGA--------YLCHCDDGFKAGPNNDCVDVNECR 237
N C+ EC + G LP + Y+C C GF G + + DVNEC
Sbjct: 233 SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGF-TGIHCE-EDVNECS 290
Query: 238 EGGMVCRN-GRCRNTVGSFRCECAPGYTLTA---DGRNCRDV-DECDELPHPCGRDGN-- 290
C+N G C N G++ C C P L+ GR+C D+ C C +G
Sbjct: 291 SN--PCQNGGTCENLPGNYTCHC-PFDNLSRTFYGGRDCSDILLGCTH--QQCLNNGTCI 345
Query: 291 PSCTNTNGGYECSCGAGW 308
P + G+ C C +G+
Sbjct: 346 PHFQDGQHGFSCLCPSGY 363
Score = 72.9 bits (171), Expect = 4e-12
Identities = 65/240 (27%), Positives = 95/240 (39%), Gaps = 28/240 (11%)
Query: 405 PDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDG 463
P +F++I + L L+ C P C+ GG C + S+ C CP G+ G
Sbjct: 1008 PQEEQFLKISTNSVVTGCL--QLNVCNSNP--CLHGGNCEDIYSSYHCSCPLGW----SG 1059
Query: 464 LSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGPDQTC-VDVDECAEGRASCT 521
C ++ DEC +P C +G CS+ Y C C PG+T C VD+D C + +
Sbjct: 1060 KHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEPGYT---GVNCEVDIDNCQSHQCANG 1114
Query: 522 FRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACENVVGSYICKCPEGYR 581
C + + C C + G CR + VC + N+ C E
Sbjct: 1115 ATCISHTNGYSCLCFGNFT----GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1167
Query: 582 RTSA---PQDSENACE-DINECEEQEDLCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
P + CE DI+EC + +GG+C + F C CD F D D
Sbjct: 1168 ELKCMCRPGFTGEWCEKDIDEC-ASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1226
Score = 67.7 bits (158), Expect = 2e-10
Identities = 64/231 (27%), Positives = 92/231 (39%), Gaps = 43/231 (18%)
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRRC-VDRDECKELPYVCAG 330
C ++ C+ +PC GN C + Y CSC GW G+ C ++ DEC P C
Sbjct: 1025 CLQLNVCNS--NPCLHGGN--CEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIH 1076
Query: 331 GECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRC-HRARPLQLARPECCC 389
G C + Y C C G+ T C E+ D ++ +C + A + C
Sbjct: 1077 GNCSDRVAAYHCTCEPGY----TGVNC-----EVDIDNCQSHQCANGATCISHTNGYSCL 1127
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSF 449
G G++C + P + +C G + NLT C GG C
Sbjct: 1128 CFGNFTGKFCRQSRLPST-----VC--GNEKTNLT-----C------YNGGNCTEFQTEL 1169
Query: 450 RCECPDGYVLAPDGLSC-VDADECALDPRICGNGTCSNTRGGYECQCSPGF 499
+C C G+ G C D DECA DP + G G C + ++C C F
Sbjct: 1170 KCMCRPGFT----GEWCEKDIDECASDPCVNG-GLCQDLLNKFQCLCDVAF 1215
Score = 67.7 bits (158), Expect = 2e-10
Identities = 45/159 (28%), Positives = 66/159 (41%), Gaps = 13/159 (8%)
Query: 68 IDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCV 127
IDEC P C G C D + C C+ GY N D+D C C A C+
Sbjct: 1066 IDECFSNP--CIHGNCSDRVAAYHCTCEPGYTGVNCE---VDIDNCQ--SHQCANGATCI 1118
Query: 128 NLPGAFECRCPPGYRLTPSLDECEDVDECGDQR---IC-DHGDCRNTIGSYRCECKPGYT 183
+ + C C + CG+++ C + G+C +C C+PG+T
Sbjct: 1119 SHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1178
Query: 184 LRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGF 222
E +D+DEC+ P G C++L + C CD F
Sbjct: 1179 -GEWCEKDIDECASD-PCVNGGLCQDLLNKFQCLCDVAF 1215
Score = 66.9 bits (156), Expect = 3e-10
Identities = 62/234 (26%), Positives = 90/234 (38%), Gaps = 35/234 (14%)
Query: 59 NPVTNETKPIDECDIMPQLCKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRP 118
N V ++ C+ P L G C D + + C C G+ + H ++DEC + P
Sbjct: 1019 NSVVTGCLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGW---SGKHCELNIDEC-FSNP 1073
Query: 119 PCRGMAQCVNLPGAFECRCPPGYRLTPSLDECE-DVDECGDQRICDHGDCRNTIGSYRCE 177
G C + A+ C C PGY CE D+D C + + C + Y C
Sbjct: 1074 CIHG--NCSDRVAAYHCTCEPGYTGV----NCEVDIDNCQSHQCANGATCISHTNGYSCL 1127
Query: 178 CKPGYTLRENVCRDVDECSRPRPVCRN----------GTCENLPGAYLCHCDDGFKAGPN 227
C +T CR + P VC N G C C C GF G
Sbjct: 1128 CFGNFT--GKFCR---QSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF-TGEW 1181
Query: 228 NDCVDVNECREGGMVCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDEL 281
+ D++EC V G C++ + F+C C + G C +VD D+L
Sbjct: 1182 CE-KDIDECASDPCV-NGGLCQDLLNKFQCLCDVAFA----GERC-EVDLADDL 1228
Score = 54.8 bits (126), Expect = 1e-06
Identities = 43/113 (38%), Positives = 55/113 (48%), Gaps = 17/113 (15%)
Query: 747 DVDECAAIP----GLCAPG--RFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTD 799
D DECA+ P +C G + C C PGY+ G C +VDECA P + C N
Sbjct: 148 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQ--GRHCDLEVDECASDPCKNEATCLNEI 205
Query: 800 GSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGY 851
G Y C+C Y GA C D++EC +++ CQ SN E E S E Y
Sbjct: 206 GRYTCICPHNYS-GYTGAQCEIDLNEC--NSNPCQ---SNGE-CVELSSEKQY 251
Score = 48.8 bits (111), Expect = 8e-05
Identities = 50/175 (28%), Positives = 67/175 (38%), Gaps = 31/175 (17%)
Query: 68 IDECDIMPQLCK-PGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQC 126
+DEC P CK TC + + C C H Y + D++EC+ PC+ +C
Sbjct: 187 VDECASDP--CKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNECNSN--PCQSNGEC 242
Query: 127 VNL------------PGAFE--------CRCPPGYRLTPSLDECEDVDECGDQRICDHGD 166
V L P +F C C PG+ + EDV+EC + G
Sbjct: 243 VELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFT---GIHCEEDVNECSSNPCQNGGT 299
Query: 167 CRNTIGSYRCECKPGYTLRENVCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDG 221
C N G+Y C C P L D CS C + C N G + H DG
Sbjct: 300 CENLPGNYTCHC-PFDNLSRTFYGGRD-CSDILLGCTHQQCLN-NGTCIPHFQDG 351
Score = 45.2 bits (102), Expect = 0.001
Identities = 28/94 (29%), Positives = 36/94 (38%), Gaps = 8/94 (8%)
Query: 763 FRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 820
F C C PGY +G +C + C +CH C+C GY G C
Sbjct: 94 FLCKCPPGY--SGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYA----GRFCEI 147
Query: 821 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 854
D DEC +C + Y C C GY+ R
Sbjct: 148 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGR 181
Score = 39.9 bits (89), Expect = 0.038
Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 20/100 (20%)
Query: 765 CVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLC------RTGYELDEDGA 817
C+C PG+ G C DV+EC+ P C N G+Y C C RT Y G
Sbjct: 271 CICQPGF--TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFY----GGR 324
Query: 818 NCRDV------DECERDTHTCQQICSNTEGSYECSCEDGY 851
+C D+ +C + TC + + + C C GY
Sbjct: 325 DCSDILLGCTHQQC-LNNGTCIPHFQDGQHGFSCLCPSGY 363
Score = 39.1 bits (87), Expect = 0.066
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
Query: 764 RCVCGPGYRPAGEVCA-DVDECAVRPPPCDQLCHNTDGSYDCLCRTGY 810
+C+C PG+ GE C D+DECA P LC + + CLC +
Sbjct: 1170 KCMCRPGF--TGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1215
Score = 38.7 bits (86), Expect = 0.087
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 6/75 (8%)
Query: 778 CADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQIC 836
C ++ C P C + SY C C G+ G +C ++DEC + C
Sbjct: 1025 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWS----GKHCELNIDECFSNP-CIHGNC 1079
Query: 837 SNTEGSYECSCEDGY 851
S+ +Y C+CE GY
Sbjct: 1080 SDRVAAYHCTCEPGY 1094
Score = 37.1 bits (82), Expect = 0.27
Identities = 32/119 (26%), Positives = 45/119 (37%), Gaps = 20/119 (16%)
Query: 747 DVDECAAIP---GLCAP--GRFRCVCGPGYRPAGEVC-ADVDECAVRPPPCDQLCHNTDG 800
++DEC + P G C+ + C C PGY G C D+D C C +
Sbjct: 1065 NIDECFSNPCIHGNCSDRVAAYHCTCEPGY--TGVNCEVDIDNCQSHQCANGATCISHTN 1122
Query: 801 SYDCLCRTGYELDEDGANCRD------VDECERDTHTCQQ--ICSNTEGSYECSCEDGY 851
Y CLC + G CR V E+ TC C+ + +C C G+
Sbjct: 1123 GYSCLCFGNF----TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF 1177
Score = 33.1 bits (72), Expect = 4.3
Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 795 CHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEK 853
C C+CR G+ G C +D+DEC D +C + ++C C+ +
Sbjct: 1162 CTEFQTELKCMCRPGFT----GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF-- 1215
Query: 854 RGDAC 858
G+ C
Sbjct: 1216 AGERC 1220
Score = 32.7 bits (71), Expect = 5.7
Identities = 19/72 (26%), Positives = 27/72 (37%), Gaps = 8/72 (11%)
Query: 505 QTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHA 564
Q C + C CH+ F C+CP G C ++ C P CPH
Sbjct: 771 QGCAGDNSCKSNPCHNGGVCHSRWDDFSCSCP----ALTSGKACEEVQWCGFSP--CPHG 824
Query: 565 --CENVVGSYIC 574
C+ V+ + C
Sbjct: 825 AQCQPVLQGFEC 836
>BC096103-1|AAH96103.1| 763|Homo sapiens NELL1 protein protein.
Length = 763
Score = 105 bits (252), Expect = 7e-22
Identities = 70/203 (34%), Positives = 87/203 (42%), Gaps = 16/203 (7%)
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGCDHGY-EHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
C P+ + C + T C C GY S C D+DEC+ C CVNL
Sbjct: 395 CAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNL 454
Query: 130 PGAFECRCPPGYRLTPSLDECEDVDECGD-QRICD-HGDCRNTIGSYRCECKPGYTLREN 187
PG + C C PGY C + DECG Q CD + C NT+ + C CKPGY
Sbjct: 455 PGLYRCDCVPGYIRVDDF-SCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGT 513
Query: 188 VCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN- 245
+CR E CR GTC P C C GF G + + D++EC C N
Sbjct: 514 ICRAFCE-----EGCRYGGTCV-APNK--CVCPSGF-TGSHCE-KDIDECALRTHTCWND 563
Query: 246 GRCRNTVGSFRCECAPGYTLTAD 268
C N G F C C G + + D
Sbjct: 564 SACINLAGGFDCLCPSGPSCSGD 586
Score = 103 bits (248), Expect = 2e-21
Identities = 91/326 (27%), Positives = 123/326 (37%), Gaps = 31/326 (9%)
Query: 316 VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCH 375
VD D C+ ECR + C P D + ++C + G
Sbjct: 287 VDGDHCRNCTCKSGAVECRRMS----CP-PLNCSPDSLPVHIAGQCCKVCRPKCIYGGKV 341
Query: 376 RARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPD 435
A ++ C G + E CP + +E I + + + C P
Sbjct: 342 LAEGQRILTKSCWECRGGVLVKITEMCPPLNCSEKDHILPENQCC-RVCRGHNFCAEGPK 400
Query: 436 VCVGGRCVNTDGSFRCECPDGYV-LAPDGLSCVDADECALDPRIC-GNGTCSNTRGGYEC 493
C N + CEC GY+ + D C D DECA C N C N G Y C
Sbjct: 401 CGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRC 460
Query: 494 QCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDI 551
C PG+ + D +C + DEC G+ +C C NT CTC GY +G CR
Sbjct: 461 DCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY--VGNGTICRAF 518
Query: 552 DECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLC-SGG 609
E C + V C CP G+ + + CE DI+EC + C +
Sbjct: 519 CE-----EGCRYG-GTCVAPNKCVCPSGF--------TGSHCEKDIDECALRTHTCWNDS 564
Query: 610 VCINTDGSFLCDCDAGFEPSEDGTDC 635
CIN G F C C +G PS G DC
Sbjct: 565 ACINLAGGFDCLCPSG--PSCSG-DC 587
Score = 91.1 bits (216), Expect = 2e-17
Identities = 108/397 (27%), Positives = 154/397 (38%), Gaps = 51/397 (12%)
Query: 188 VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA--GPNNDCVDVNECREGGMVCR- 244
VCR + C+ N C+N C C G+ + G + C D++EC C
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHA 447
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
N C N G +RC+C PGY + D +C + DEC H C D N CTNT G+ C+C
Sbjct: 448 NTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNC--DENAICTNTVQGHSCTC 504
Query: 305 GAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVC---VDE 360
G+ VG + R C+E C GG C N C CP+G+ T + C +DE
Sbjct: 505 KPGY--VGNGTICRAFCEE---GCRYGGTCVAPN---KCVCPSGF----TGSHCEKDIDE 552
Query: 361 RKELCYDEWEAGRCHRARP----LQLARPEC---CCSEGA------AWGRYCERCPAPDS 407
+ W C L + P C C EG W +RC
Sbjct: 553 CALRTHTCWNDSACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCSVCSC 612
Query: 408 AEFMRIC-QGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
+ C + N + DL C D V +C++ +G D + + C
Sbjct: 613 KDGKIFCRRTACDCQNPSADL-FCCPECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQCRC 671
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP---DQTCVDVDE-CAE--GRASC 520
++ E P C N +C T E +C P P D D+ + C + G +
Sbjct: 672 LEG-EVDCWPLTCPNLSCEYT-AILEGECCPRCVSDPCLADNITYDIRKTCLDSYGVSRL 729
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRDID-ECVQ 556
+ AGS TC +G C +D EC+Q
Sbjct: 730 SGSVWTMAGSPCTTCK-----CKNGRVCCSVDFECLQ 761
Score = 84.6 bits (200), Expect = 1e-15
Identities = 71/248 (28%), Positives = 94/248 (37%), Gaps = 47/248 (18%)
Query: 217 HCDDGFKAGPNNDCVDV----NECREGGMVCRNGRCRNTVGSFRCECAPGY-TLTADGRN 271
+C + P N C V N C EG N C+N CEC GY ++ D
Sbjct: 372 NCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAY 431
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW-KLVGRRCVDRDECKELPYVC-A 329
C D+DEC H C N C N G Y C C G+ ++ C + DEC + C
Sbjct: 432 CEDIDECAAKMHYC--HANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDE 489
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C N G+ C C G+ + T +C +E C G C +A +C C
Sbjct: 490 NAICTNTVQGHSCTCKPGYVGNGT--ICRAFCEEGCR---YGGTC-------VAPNKCVC 537
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGS 448
G G +CE+ D+DEC +R C C+N G
Sbjct: 538 PSGFT-GSHCEK------------------------DIDECALRTHTCWNDSACINLAGG 572
Query: 449 FRCECPDG 456
F C CP G
Sbjct: 573 FDCLCPSG 580
Score = 70.1 bits (164), Expect = 3e-11
Identities = 36/101 (35%), Positives = 49/101 (48%), Gaps = 8/101 (7%)
Query: 765 CVCGPGY---RPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANC 819
C C GY + C D+DECA + C + +C N G Y C C GY + D +C
Sbjct: 416 CECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY-IRVDDFSC 474
Query: 820 RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
+ DEC H C + IC+NT + C+C+ GY G C
Sbjct: 475 TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTIC 515
Score = 61.7 bits (143), Expect = 1e-08
Identities = 65/232 (28%), Positives = 90/232 (38%), Gaps = 52/232 (22%)
Query: 425 QDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADE------------ 471
+D+DEC + C CVN G +RC+C GY+ D SC + DE
Sbjct: 433 EDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDD-FSCTEHDECGSGQHNCDENA 491
Query: 472 ----------CALDPRICGNGT-----CSN--TRGGY-----ECQCSPGFTQGPDQTCVD 509
C P GNGT C GG +C C GFT + D
Sbjct: 492 ICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEK--D 549
Query: 510 VDECAEGRASC--TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN 567
+DECA +C C N AG F C CP G + + D H + Q + C
Sbjct: 550 IDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCS- 608
Query: 568 VVGSYICKCPEG---YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDG 616
+C C +G RRT+ D +N D+ C E + + C++ +G
Sbjct: 609 -----VCSCKDGKIFCRRTAC--DCQNPSADLFCCPECDTRVT-SQCLDQNG 652
Score = 52.0 bits (119), Expect = 9e-06
Identities = 32/85 (37%), Positives = 40/85 (47%), Gaps = 13/85 (15%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGY-RPAGEVCADVDECAVRPPPCDQ--LC 795
D+DECAA C PG +RC C PGY R C + DEC CD+ +C
Sbjct: 434 DIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAIC 493
Query: 796 HNTDGSYDCLCRTGYELDEDGANCR 820
NT + C C+ GY +G CR
Sbjct: 494 TNTVQGHSCTCKPGYV--GNGTICR 516
Score = 49.6 bits (113), Expect = 5e-05
Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 13/95 (13%)
Query: 765 CVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDVD 823
C C PGY G +C E R C + C+C +G+ G++C +D+D
Sbjct: 502 CTCKPGYVGNGTICRAFCEEGCR---YGGTCVAPN---KCVCPSGFT----GSHCEKDID 551
Query: 824 ECERDTHTC--QQICSNTEGSYECSCEDGYEKRGD 856
EC THTC C N G ++C C G GD
Sbjct: 552 ECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGD 586
Score = 47.2 bits (107), Expect = 2e-04
Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 14/99 (14%)
Query: 756 GLC-APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYE 811
G C AP + CVC G+ G C D+DECA+R C D C N G +DCLC +G
Sbjct: 527 GTCVAPNK--CVCPSGF--TGSHCEKDIDECALRTHTCWNDSACINLAGGFDCLCPSGPS 582
Query: 812 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
D C + H Q + CSC+DG
Sbjct: 583 CSGD---CPHEGGLK---HNGQVWTLKEDRCSVCSCKDG 615
>BC096100-1|AAH96100.1| 763|Homo sapiens NELL1 protein protein.
Length = 763
Score = 105 bits (252), Expect = 7e-22
Identities = 70/203 (34%), Positives = 87/203 (42%), Gaps = 16/203 (7%)
Query: 71 CDIMPQLCKPGTCHDTPTGFQCGCDHGY-EHDNTSHLCRDVDECSWGRPPCRGMAQCVNL 129
C P+ + C + T C C GY S C D+DEC+ C CVNL
Sbjct: 395 CAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNL 454
Query: 130 PGAFECRCPPGYRLTPSLDECEDVDECGD-QRICD-HGDCRNTIGSYRCECKPGYTLREN 187
PG + C C PGY C + DECG Q CD + C NT+ + C CKPGY
Sbjct: 455 PGLYRCDCVPGYIRVDDF-SCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGT 513
Query: 188 VCRDVDECSRPRPVCR-NGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRN- 245
+CR E CR GTC P C C GF G + + D++EC C N
Sbjct: 514 ICRAFCE-----EGCRYGGTCV-APNK--CVCPSGF-TGSHCE-KDIDECALRTHTCWND 563
Query: 246 GRCRNTVGSFRCECAPGYTLTAD 268
C N G F C C G + + D
Sbjct: 564 SACINLAGGFDCLCPSGPSCSGD 586
Score = 103 bits (247), Expect = 3e-21
Identities = 91/326 (27%), Positives = 123/326 (37%), Gaps = 31/326 (9%)
Query: 316 VDRDECKELPYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCH 375
VD D C+ ECR + C P D + ++C + G
Sbjct: 287 VDGDHCRNCTCKSGAVECRRMS----CP-PLNCSPDSLPVHIAGQCCKVCRPKCIYGGKV 341
Query: 376 RARPLQLARPECCCSEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPD 435
A ++ C G + E CP + +E I + + + C P
Sbjct: 342 LAEGQRILTKSCRECRGGVLVKITEMCPPLNCSEKDHILPENQCC-RVCRGHNFCAEGPK 400
Query: 436 VCVGGRCVNTDGSFRCECPDGYV-LAPDGLSCVDADECALDPRIC-GNGTCSNTRGGYEC 493
C N + CEC GY+ + D C D DECA C N C N G Y C
Sbjct: 401 CGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRC 460
Query: 494 QCSPGFTQGPDQTCVDVDECAEGRASCTFR--CHNTAGSFRCTCPYGYAVAADGVHCRDI 551
C PG+ + D +C + DEC G+ +C C NT CTC GY +G CR
Sbjct: 461 DCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY--VGNGTICRAF 518
Query: 552 DECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACE-DINECEEQEDLC-SGG 609
E C + V C CP G+ + + CE DI+EC + C +
Sbjct: 519 CE-----EGCRYG-GTCVAPNKCVCPSGF--------TGSHCEKDIDECALRTHTCWNDS 564
Query: 610 VCINTDGSFLCDCDAGFEPSEDGTDC 635
CIN G F C C +G PS G DC
Sbjct: 565 ACINLAGGFDCLCPSG--PSCSG-DC 587
Score = 91.1 bits (216), Expect = 2e-17
Identities = 108/397 (27%), Positives = 154/397 (38%), Gaps = 51/397 (12%)
Query: 188 VCRDVDECSRPRPVCRNGTCENLPGAYLCHCDDGFKA--GPNNDCVDVNECREGGMVCR- 244
VCR + C+ N C+N C C G+ + G + C D++EC C
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHA 447
Query: 245 NGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSC 304
N C N G +RC+C PGY + D +C + DEC H C D N CTNT G+ C+C
Sbjct: 448 NTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNC--DENAICTNTVQGHSCTC 504
Query: 305 GAGWKLVGRRCVDRDECKELPYVCA-GGECRNFNGGYVCECPAGWRFDKTAAVC---VDE 360
G+ VG + R C+E C GG C N C CP+G+ T + C +DE
Sbjct: 505 KPGY--VGNGTICRAFCEE---GCRYGGTCVAPN---KCVCPSGF----TGSHCEKDIDE 552
Query: 361 RKELCYDEWEAGRCHRARP----LQLARPEC---CCSEGA------AWGRYCERCPAPDS 407
+ W C L + P C C EG W +RC
Sbjct: 553 CALRTHTCWNDSACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCSVCSC 612
Query: 408 AEFMRIC-QGGMGRPNLTQDLDECRVRPDVCVGGRCVNTDGSFRCECPDGYVLAPDGLSC 466
+ C + N + DL C D V +C++ +G D + + C
Sbjct: 613 KDGKIFCRRTACDCQNPSADL-FCCPECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQCRC 671
Query: 467 VDADECALDPRICGNGTCSNTRGGYECQCSPGFTQGP---DQTCVDVDE-CAE--GRASC 520
++ E P C N +C T E +C P P D D+ + C + G +
Sbjct: 672 LEG-EVDCWPLTCPNLSCEYT-AILEGECCPRCVSDPCLADNITYDIRKTCLDSYGVSRL 729
Query: 521 TFRCHNTAGSFRCTCPYGYAVAADGVHCRDID-ECVQ 556
+ AGS TC +G C +D EC+Q
Sbjct: 730 SGSVWTMAGSPCTTCK-----CKNGRVCCSVDFECLQ 761
Score = 84.6 bits (200), Expect = 1e-15
Identities = 71/248 (28%), Positives = 94/248 (37%), Gaps = 47/248 (18%)
Query: 217 HCDDGFKAGPNNDCVDV----NECREGGMVCRNGRCRNTVGSFRCECAPGY-TLTADGRN 271
+C + P N C V N C EG N C+N CEC GY ++ D
Sbjct: 372 NCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAY 431
Query: 272 CRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGW-KLVGRRCVDRDECKELPYVC-A 329
C D+DEC H C N C N G Y C C G+ ++ C + DEC + C
Sbjct: 432 CEDIDECAAKMHYC--HANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDE 489
Query: 330 GGECRNFNGGYVCECPAGWRFDKTAAVCVDERKELCYDEWEAGRCHRARPLQLARPECCC 389
C N G+ C C G+ + T +C +E C G C +A +C C
Sbjct: 490 NAICTNTVQGHSCTCKPGYVGNGT--ICRAFCEEGCR---YGGTC-------VAPNKCVC 537
Query: 390 SEGAAWGRYCERCPAPDSAEFMRICQGGMGRPNLTQDLDECRVRPDVCVG-GRCVNTDGS 448
G G +CE+ D+DEC +R C C+N G
Sbjct: 538 PSGFT-GSHCEK------------------------DIDECALRTHTCWNDSACINLAGG 572
Query: 449 FRCECPDG 456
F C CP G
Sbjct: 573 FDCLCPSG 580
Score = 70.1 bits (164), Expect = 3e-11
Identities = 36/101 (35%), Positives = 49/101 (48%), Gaps = 8/101 (7%)
Query: 765 CVCGPGY---RPAGEVCADVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANC 819
C C GY + C D+DECA + C + +C N G Y C C GY + D +C
Sbjct: 416 CECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY-IRVDDFSC 474
Query: 820 RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC 858
+ DEC H C + IC+NT + C+C+ GY G C
Sbjct: 475 TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTIC 515
Score = 61.7 bits (143), Expect = 1e-08
Identities = 65/232 (28%), Positives = 90/232 (38%), Gaps = 52/232 (22%)
Query: 425 QDLDECRVRPDVCVGGR-CVNTDGSFRCECPDGYVLAPDGLSCVDADE------------ 471
+D+DEC + C CVN G +RC+C GY+ D SC + DE
Sbjct: 433 EDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDD-FSCTEHDECGSGQHNCDENA 491
Query: 472 ----------CALDPRICGNGT-----CSN--TRGGY-----ECQCSPGFTQGPDQTCVD 509
C P GNGT C GG +C C GFT + D
Sbjct: 492 ICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEK--D 549
Query: 510 VDECAEGRASC--TFRCHNTAGSFRCTCPYGYAVAADGVHCRDIDECVQEPRVCPHACEN 567
+DECA +C C N AG F C CP G + + D H + Q + C
Sbjct: 550 IDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCS- 608
Query: 568 VVGSYICKCPEG---YRRTSAPQDSENACEDINECEEQEDLCSGGVCINTDG 616
+C C +G RRT+ D +N D+ C E + + C++ +G
Sbjct: 609 -----VCSCKDGKIFCRRTAC--DCQNPSADLFCCPECDTRVT-SQCLDQNG 652
Score = 52.0 bits (119), Expect = 9e-06
Identities = 32/85 (37%), Positives = 40/85 (47%), Gaps = 13/85 (15%)
Query: 747 DVDECAAIPGLC--------APGRFRCVCGPGY-RPAGEVCADVDECAVRPPPCDQ--LC 795
D+DECAA C PG +RC C PGY R C + DEC CD+ +C
Sbjct: 434 DIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAIC 493
Query: 796 HNTDGSYDCLCRTGYELDEDGANCR 820
NT + C C+ GY +G CR
Sbjct: 494 TNTVQGHSCTCKPGYV--GNGTICR 516
Score = 49.6 bits (113), Expect = 5e-05
Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 13/95 (13%)
Query: 765 CVCGPGYRPAGEVCADVDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDVD 823
C C PGY G +C E R C + C+C +G+ G++C +D+D
Sbjct: 502 CTCKPGYVGNGTICRAFCEEGCR---YGGTCVAPN---KCVCPSGFT----GSHCEKDID 551
Query: 824 ECERDTHTC--QQICSNTEGSYECSCEDGYEKRGD 856
EC THTC C N G ++C C G GD
Sbjct: 552 ECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGD 586
Score = 47.2 bits (107), Expect = 2e-04
Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 14/99 (14%)
Query: 756 GLC-APGRFRCVCGPGYRPAGEVCA-DVDECAVRPPPC--DQLCHNTDGSYDCLCRTGYE 811
G C AP + CVC G+ G C D+DECA+R C D C N G +DCLC +G
Sbjct: 527 GTCVAPNK--CVCPSGF--TGSHCEKDIDECALRTHTCWNDSACINLAGGFDCLCPSGPS 582
Query: 812 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 850
D C + H Q + CSC+DG
Sbjct: 583 CSGD---CPHEGGLK---HNGQVWTLKEDRCSVCSCKDG 615
>BC035784-1|AAH35784.1| 439|Homo sapiens hypothetical protein
FLJ37440 protein.
Length = 439
Score = 105 bits (252), Expect = 7e-22
Identities = 73/201 (36%), Positives = 86/201 (42%), Gaps = 28/201 (13%)
Query: 427 LDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGNGT- 483
+ EC +P C GG CV +RC CP G G C A A + + G+
Sbjct: 137 ISECSSQP--CQNGGTCVEGVNQYRCICPPGRT----GNRCQHQAQTAAPEGSVAGDSAF 190
Query: 484 -----CSNTRGGYECQCSPGFT---QGPDQTCVDVDECA----EGRAS-CTFRCHNTAGS 530
C+ C C GF D C DV+EC EGR C C NT GS
Sbjct: 191 SRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGS 250
Query: 531 FRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH--ACENVVGSYIC---KCPEGYRRTSA 585
+RCTCP GY ADG C D+DECV VCP C N GS+ C +CPEG S
Sbjct: 251 YRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSY 310
Query: 586 PQDSENACEDINECEEQEDLC 606
+ S CE N C C
Sbjct: 311 VKTSPFQCER-NPCPMDSRPC 330
Score = 101 bits (241), Expect = 1e-20
Identities = 70/225 (31%), Positives = 92/225 (40%), Gaps = 23/225 (10%)
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENV 188
L G C P T C + EC Q + G C + YRC C PG T N
Sbjct: 113 LVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRT--GNR 170
Query: 189 CRDVDECSRPR-------PVCRNGTCENLPGAYLCHCDDGFK---AGPNNDCVDVNECRE 238
C+ + + P R C + A C C+ GF A ++ C DVNEC
Sbjct: 171 CQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECEL 230
Query: 239 GGM-----VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
G +C + C NT GS+RC C GY ADG++C DVDEC L C + +C
Sbjct: 231 YGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQ--GTTC 287
Query: 294 TNTNGGYEC---SCGAGWKLVGRRCVDRDECKELPYVCAGGECRN 335
NT G ++C C G V +C+ P CR+
Sbjct: 288 INTGGSFQCVSPECPEGSGNVSYVKTSPFQCERNPCPMDSRPCRH 332
Score = 99.1 bits (236), Expect = 6e-20
Identities = 72/193 (37%), Positives = 87/193 (45%), Gaps = 28/193 (14%)
Query: 449 FRCECPDGYVLAPDGL------SCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFT- 500
FR P V P+G C EC+ P C NG TC Y C C PG T
Sbjct: 111 FRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQP--CQNGGTCVEGVNQYRCICPPGRTG 168
Query: 501 ---QGPDQTCVDVDECAEGRA-SCTFRCHNTAGSFRCTCPYGY---AVAADGVHCRDIDE 553
Q QT A A S RC + C+C G+ A D V C+D++E
Sbjct: 169 NRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSV-CQDVNE 227
Query: 554 CV---QE--PRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLC-S 607
C QE PR+C HAC N GSY C CP GYR + +CED++EC + +C
Sbjct: 228 CELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLA----DGKSCEDVDECVGLQPVCPQ 283
Query: 608 GGVCINTDGSFLC 620
G CINT GSF C
Sbjct: 284 GTTCINTGGSFQC 296
Score = 86.2 bits (204), Expect = 4e-16
Identities = 64/204 (31%), Positives = 86/204 (42%), Gaps = 25/204 (12%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRC 137
C PG P+ C +G H CR + ECS PC+ CV + C C
Sbjct: 107 CNPGFRLVGPSSVVC-LPNGTWTGEQPH-CRGISECS--SQPCQNGGTCVEGVNQYRCIC 162
Query: 138 PPGYRLTPSLDECE----DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR----ENVC 189
PPG + + + GD C + C C+ G+ L ++VC
Sbjct: 163 PPGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVC 222
Query: 190 RDVDEC------SRPRPVCRNGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMV 242
+DV+EC RPR +C + C N PG+Y C C G++ C DV+EC V
Sbjct: 223 QDVNECELYGQEGRPR-LCMH-ACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPV 280
Query: 243 CRNG-RCRNTVGSFRC---ECAPG 262
C G C NT GSF+C EC G
Sbjct: 281 CPQGTTCINTGGSFQCVSPECPEG 304
Score = 84.2 bits (199), Expect = 2e-15
Identities = 69/229 (30%), Positives = 96/229 (41%), Gaps = 32/229 (13%)
Query: 145 PSLDECEDVDECGDQRICDHG---DCR---NTIGSYRCECKPG--YTLRENVCRDVDECS 196
P+L+ D + G + + DH C +G C P +T + CR + ECS
Sbjct: 82 PALNTPADGRKFGSKYLVDHEVHFTCNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECS 141
Query: 197 RPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMV-----CRNGRCRNT 251
+P GTC Y C C G + G EG + R RC
Sbjct: 142 S-QPCQNGGTCVEGVNQYRCICPPG-RTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQV 199
Query: 252 VGSFRCECAPGYTLT--ADGRNCRDVDECDELPHPCGRDGNP-----SCTNTNGGYECSC 304
+ C C G+ L+ A C+DV+EC+ G++G P +C NT G Y C+C
Sbjct: 200 ERAQHCSCEAGFHLSGAAGDSVCQDVNECELY----GQEGRPRLCMHACVNTPGSYRCTC 255
Query: 305 GAGWKLV--GRRCVDRDECKELPYVC-AGGECRNFNGGYVC---ECPAG 347
G++ + G+ C D DEC L VC G C N G + C ECP G
Sbjct: 256 PGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
Score = 80.6 bits (190), Expect = 2e-14
Identities = 50/145 (34%), Positives = 66/145 (45%), Gaps = 10/145 (6%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTS--HLCRDVDECS-WGRP--PCRGMAQCVNLPGAFECRC 137
C C C+ G+ + +C+DV+EC +G+ P M CVN PG++ C C
Sbjct: 196 CAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTC 255
Query: 138 PPGYRLTPSLDECEDVDEC-GDQRICDHG-DCRNTIGSYRC---ECKPGYTLRENVCRDV 192
P GYR CEDVDEC G Q +C G C NT GS++C EC G V
Sbjct: 256 PGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYVKTSP 315
Query: 193 DECSRPRPVCRNGTCENLPGAYLCH 217
+C R + C +LP H
Sbjct: 316 FQCERNPCPMDSRPCRHLPKTISFH 340
Score = 72.5 bits (170), Expect = 6e-12
Identities = 41/100 (41%), Positives = 49/100 (49%), Gaps = 14/100 (14%)
Query: 765 CVCGPGYRPAG----EVCADVDECAV-----RPPPCDQLCHNTDGSYDCLCRTGYELDED 815
C C G+ +G VC DV+EC + RP C C NT GSY C C GY D
Sbjct: 205 CSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLAD 264
Query: 816 GANCRDVDECERDTHTCQQ--ICSNTEGSYEC---SCEDG 850
G +C DVDEC C Q C NT GS++C C +G
Sbjct: 265 GKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
Score = 61.7 bits (143), Expect = 1e-08
Identities = 47/157 (29%), Positives = 60/157 (38%), Gaps = 21/157 (13%)
Query: 495 CSPGFT-QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DID 552
C P T G C + EC+ C +RC CP G G C+
Sbjct: 121 CLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRT----GNRCQHQAQ 176
Query: 553 ECVQEPRVCPHA-------CENVVGSYICKCPEGYRRTSAPQDSENACEDINECE--EQE 603
E V + C V + C C G+ + A DS C+D+NECE QE
Sbjct: 177 TAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDS--VCQDVNECELYGQE 234
Query: 604 D---LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
LC C+NT GS+ C C G+ DG C D
Sbjct: 235 GRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCED 270
Score = 58.4 bits (135), Expect = 1e-07
Identities = 44/159 (27%), Positives = 58/159 (36%), Gaps = 14/159 (8%)
Query: 211 PGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADG 269
P + +C +G G C ++EC C+NG C V +RC C PG T
Sbjct: 116 PSSVVC-LPNGTWTGEQPHCRGISEC--SSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQ 172
Query: 270 RNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR----CVDRDECKEL- 324
+ + P C CSC AG+ L G C D +EC+
Sbjct: 173 HQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYG 232
Query: 325 ----PYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD 359
P +C C N G Y C CP G+R C D
Sbjct: 233 QEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCED 270
Score = 56.0 bits (129), Expect = 5e-07
Identities = 41/134 (30%), Positives = 55/134 (41%), Gaps = 31/134 (23%)
Query: 748 VDECAAIP----GLCAPG--RFRCVCGPGYR------------PAGEVCADVDECAVRPP 789
+ EC++ P G C G ++RC+C PG P G V D R P
Sbjct: 137 ISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGD--SAFSRAP 194
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGAN--CRDVDECER-----DTHTCQQICSNTEGS 842
C Q+ + + C C G+ L + C+DV+ECE C C NT GS
Sbjct: 195 RCAQV----ERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGS 250
Query: 843 YECSCEDGYEKRGD 856
Y C+C GY D
Sbjct: 251 YRCTCPGGYRTLAD 264
Score = 55.6 bits (128), Expect = 7e-07
Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 9/100 (9%)
Query: 50 CGEKPGEYINPVTNET--KPIDECDIMPQLCKPGTC-H---DTPTGFQCGCDHGYEHDNT 103
C + G +++ ++ + ++EC++ Q +P C H +TP ++C C GY
Sbjct: 205 CSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLAD 264
Query: 104 SHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC---RCPPG 140
C DVDEC +P C C+N G+F+C CP G
Sbjct: 265 GKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
Score = 42.7 bits (96), Expect = 0.005
Identities = 24/97 (24%), Positives = 35/97 (36%), Gaps = 1/97 (1%)
Query: 547 HCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLC 606
HCR I EC +P C V Y C CP G ++ A + + +
Sbjct: 133 HCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSA-FS 191
Query: 607 SGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
C + + C C+AGF S D + + C
Sbjct: 192 RAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNEC 228
Score = 38.3 bits (85), Expect = 0.11
Identities = 29/109 (26%), Positives = 38/109 (34%), Gaps = 6/109 (5%)
Query: 755 PGLCAPGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNTDGSYDCLC---RTG 809
PG G VC P GE C + EC+ +P C Y C+C RTG
Sbjct: 109 PGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTG 168
Query: 810 YELDEDGANCRDVDECERDTHTCQQI-CSNTEGSYECSCEDGYEKRGDA 857
D+ + C+ E + CSCE G+ G A
Sbjct: 169 NRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAA 217
>AK094759-1|BAC04416.1| 439|Homo sapiens protein ( Homo sapiens
cDNA FLJ37440 fis, clone BRAWH2006405, weakly similar to
FIBULIN-1, ISOFORM C PRECURSOR. ).
Length = 439
Score = 105 bits (252), Expect = 7e-22
Identities = 73/201 (36%), Positives = 86/201 (42%), Gaps = 28/201 (13%)
Query: 427 LDECRVRPDVCV-GGRCVNTDGSFRCECPDGYVLAPDGLSCV-DADECALDPRICGNGT- 483
+ EC +P C GG CV +RC CP G G C A A + + G+
Sbjct: 137 ISECSSQP--CQNGGTCVEGVNQYRCICPPGRT----GNRCQHQAQTAAPEGSVAGDSAF 190
Query: 484 -----CSNTRGGYECQCSPGFT---QGPDQTCVDVDECA----EGRAS-CTFRCHNTAGS 530
C+ C C GF D C DV+EC EGR C C NT GS
Sbjct: 191 SRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGS 250
Query: 531 FRCTCPYGYAVAADGVHCRDIDECVQEPRVCPH--ACENVVGSYIC---KCPEGYRRTSA 585
+RCTCP GY ADG C D+DECV VCP C N GS+ C +CPEG S
Sbjct: 251 YRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSY 310
Query: 586 PQDSENACEDINECEEQEDLC 606
+ S CE N C C
Sbjct: 311 VKTSPFQCER-NPCPMDSRPC 330
Score = 101 bits (241), Expect = 1e-20
Identities = 70/225 (31%), Positives = 92/225 (40%), Gaps = 23/225 (10%)
Query: 129 LPGAFECRCPPGYRLTPSLDECEDVDECGDQRICDHGDCRNTIGSYRCECKPGYTLRENV 188
L G C P T C + EC Q + G C + YRC C PG T N
Sbjct: 113 LVGPSSMVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRT--GNR 170
Query: 189 CRDVDECSRPR-------PVCRNGTCENLPGAYLCHCDDGFK---AGPNNDCVDVNECRE 238
C+ + + P R C + A C C+ GF A ++ C DVNEC
Sbjct: 171 CQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECEL 230
Query: 239 GGM-----VCRNGRCRNTVGSFRCECAPGYTLTADGRNCRDVDECDELPHPCGRDGNPSC 293
G +C + C NT GS+RC C GY ADG++C DVDEC L C + +C
Sbjct: 231 YGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQ--GTTC 287
Query: 294 TNTNGGYEC---SCGAGWKLVGRRCVDRDECKELPYVCAGGECRN 335
NT G ++C C G V +C+ P CR+
Sbjct: 288 INTGGSFQCVSPECPEGSGNVSYVKTSPFQCERNPCPMDSRPCRH 332
Score = 99.1 bits (236), Expect = 6e-20
Identities = 72/193 (37%), Positives = 87/193 (45%), Gaps = 28/193 (14%)
Query: 449 FRCECPDGYVLAPDGL------SCVDADECALDPRICGNG-TCSNTRGGYECQCSPGFT- 500
FR P V P+G C EC+ P C NG TC Y C C PG T
Sbjct: 111 FRLVGPSSMVCLPNGTWTGEQPHCRGISECSSQP--CQNGGTCVEGVNQYRCICPPGRTG 168
Query: 501 ---QGPDQTCVDVDECAEGRA-SCTFRCHNTAGSFRCTCPYGY---AVAADGVHCRDIDE 553
Q QT A A S RC + C+C G+ A D V C+D++E
Sbjct: 169 NRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSV-CQDVNE 227
Query: 554 CV---QE--PRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLC-S 607
C QE PR+C HAC N GSY C CP GYR + +CED++EC + +C
Sbjct: 228 CELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLA----DGKSCEDVDECVGLQPVCPQ 283
Query: 608 GGVCINTDGSFLC 620
G CINT GSF C
Sbjct: 284 GTTCINTGGSFQC 296
Score = 86.6 bits (205), Expect = 3e-16
Identities = 64/204 (31%), Positives = 86/204 (42%), Gaps = 25/204 (12%)
Query: 78 CKPGTCHDTPTGFQCGCDHGYEHDNTSHLCRDVDECSWGRPPCRGMAQCVNLPGAFECRC 137
C PG P+ C +G H CR + ECS PC+ CV + C C
Sbjct: 107 CNPGFRLVGPSSMVC-LPNGTWTGEQPH-CRGISECS--SQPCQNGGTCVEGVNQYRCIC 162
Query: 138 PPGYRLTPSLDECE----DVDECGDQRICDHGDCRNTIGSYRCECKPGYTLR----ENVC 189
PPG + + + GD C + C C+ G+ L ++VC
Sbjct: 163 PPGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVC 222
Query: 190 RDVDEC------SRPRPVCRNGTCENLPGAYLCHCDDGFKA-GPNNDCVDVNECREGGMV 242
+DV+EC RPR +C + C N PG+Y C C G++ C DV+EC V
Sbjct: 223 QDVNECELYGQEGRPR-LCMH-ACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPV 280
Query: 243 CRNG-RCRNTVGSFRC---ECAPG 262
C G C NT GSF+C EC G
Sbjct: 281 CPQGTTCINTGGSFQCVSPECPEG 304
Score = 84.2 bits (199), Expect = 2e-15
Identities = 69/229 (30%), Positives = 96/229 (41%), Gaps = 32/229 (13%)
Query: 145 PSLDECEDVDECGDQRICDHG---DCR---NTIGSYRCECKPG--YTLRENVCRDVDECS 196
P+L+ D + G + + DH C +G C P +T + CR + ECS
Sbjct: 82 PALNTPADGRKFGSKYLVDHEVHFTCNPGFRLVGPSSMVCLPNGTWTGEQPHCRGISECS 141
Query: 197 RPRPVCRNGTCENLPGAYLCHCDDGFKAGPNNDCVDVNECREGGMV-----CRNGRCRNT 251
+P GTC Y C C G + G EG + R RC
Sbjct: 142 S-QPCQNGGTCVEGVNQYRCICPPG-RTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQV 199
Query: 252 VGSFRCECAPGYTLT--ADGRNCRDVDECDELPHPCGRDGNP-----SCTNTNGGYECSC 304
+ C C G+ L+ A C+DV+EC+ G++G P +C NT G Y C+C
Sbjct: 200 ERAQHCSCEAGFHLSGAAGDSVCQDVNECELY----GQEGRPRLCMHACVNTPGSYRCTC 255
Query: 305 GAGWKLV--GRRCVDRDECKELPYVC-AGGECRNFNGGYVC---ECPAG 347
G++ + G+ C D DEC L VC G C N G + C ECP G
Sbjct: 256 PGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
Score = 80.6 bits (190), Expect = 2e-14
Identities = 50/145 (34%), Positives = 66/145 (45%), Gaps = 10/145 (6%)
Query: 83 CHDTPTGFQCGCDHGYEHDNTS--HLCRDVDECS-WGRP--PCRGMAQCVNLPGAFECRC 137
C C C+ G+ + +C+DV+EC +G+ P M CVN PG++ C C
Sbjct: 196 CAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTC 255
Query: 138 PPGYRLTPSLDECEDVDEC-GDQRICDHG-DCRNTIGSYRC---ECKPGYTLRENVCRDV 192
P GYR CEDVDEC G Q +C G C NT GS++C EC G V
Sbjct: 256 PGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYVKTSP 315
Query: 193 DECSRPRPVCRNGTCENLPGAYLCH 217
+C R + C +LP H
Sbjct: 316 FQCERNPCPMDSRPCRHLPKTISFH 340
Score = 72.5 bits (170), Expect = 6e-12
Identities = 41/100 (41%), Positives = 49/100 (49%), Gaps = 14/100 (14%)
Query: 765 CVCGPGYRPAG----EVCADVDECAV-----RPPPCDQLCHNTDGSYDCLCRTGYELDED 815
C C G+ +G VC DV+EC + RP C C NT GSY C C GY D
Sbjct: 205 CSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLAD 264
Query: 816 GANCRDVDECERDTHTCQQ--ICSNTEGSYEC---SCEDG 850
G +C DVDEC C Q C NT GS++C C +G
Sbjct: 265 GKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
Score = 61.7 bits (143), Expect = 1e-08
Identities = 47/157 (29%), Positives = 60/157 (38%), Gaps = 21/157 (13%)
Query: 495 CSPGFT-QGPDQTCVDVDECAEGRASCTFRCHNTAGSFRCTCPYGYAVAADGVHCR-DID 552
C P T G C + EC+ C +RC CP G G C+
Sbjct: 121 CLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRT----GNRCQHQAQ 176
Query: 553 ECVQEPRVCPHA-------CENVVGSYICKCPEGYRRTSAPQDSENACEDINECE--EQE 603
E V + C V + C C G+ + A DS C+D+NECE QE
Sbjct: 177 TAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDS--VCQDVNECELYGQE 234
Query: 604 D---LCSGGVCINTDGSFLCDCDAGFEPSEDGTDCID 637
LC C+NT GS+ C C G+ DG C D
Sbjct: 235 GRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCED 270
Score = 58.4 bits (135), Expect = 1e-07
Identities = 44/159 (27%), Positives = 58/159 (36%), Gaps = 14/159 (8%)
Query: 211 PGAYLCHCDDGFKAGPNNDCVDVNECREGGMVCRNG-RCRNTVGSFRCECAPGYTLTADG 269
P + +C +G G C ++EC C+NG C V +RC C PG T
Sbjct: 116 PSSMVC-LPNGTWTGEQPHCRGISEC--SSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQ 172
Query: 270 RNCRDVDECDELPHPCGRDGNPSCTNTNGGYECSCGAGWKLVGRR----CVDRDECKEL- 324
+ + P C CSC AG+ L G C D +EC+
Sbjct: 173 HQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYG 232
Query: 325 ----PYVCAGGECRNFNGGYVCECPAGWRFDKTAAVCVD 359
P +C C N G Y C CP G+R C D
Sbjct: 233 QEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCED 270
Score = 56.0 bits (129), Expect = 5e-07
Identities = 41/134 (30%), Positives = 55/134 (41%), Gaps = 31/134 (23%)
Query: 748 VDECAAIP----GLCAPG--RFRCVCGPGYR------------PAGEVCADVDECAVRPP 789
+ EC++ P G C G ++RC+C PG P G V D R P
Sbjct: 137 ISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGD--SAFSRAP 194
Query: 790 PCDQLCHNTDGSYDCLCRTGYELDEDGAN--CRDVDECER-----DTHTCQQICSNTEGS 842
C Q+ + + C C G+ L + C+DV+ECE C C NT GS
Sbjct: 195 RCAQV----ERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGS 250
Query: 843 YECSCEDGYEKRGD 856
Y C+C GY D
Sbjct: 251 YRCTCPGGYRTLAD 264
Score = 55.6 bits (128), Expect = 7e-07
Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 9/100 (9%)
Query: 50 CGEKPGEYINPVTNET--KPIDECDIMPQLCKPGTC-H---DTPTGFQCGCDHGYEHDNT 103
C + G +++ ++ + ++EC++ Q +P C H +TP ++C C GY
Sbjct: 205 CSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLAD 264
Query: 104 SHLCRDVDECSWGRPPCRGMAQCVNLPGAFEC---RCPPG 140
C DVDEC +P C C+N G+F+C CP G
Sbjct: 265 GKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
Score = 42.7 bits (96), Expect = 0.005
Identities = 24/97 (24%), Positives = 35/97 (36%), Gaps = 1/97 (1%)
Query: 547 HCRDIDECVQEPRVCPHACENVVGSYICKCPEGYRRTSAPQDSENACEDINECEEQEDLC 606
HCR I EC +P C V Y C CP G ++ A + + +
Sbjct: 133 HCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSA-FS 191
Query: 607 SGGVCINTDGSFLCDCDAGFEPSEDGTDCIDRRTGTC 643
C + + C C+AGF S D + + C
Sbjct: 192 RAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNEC 228
Score = 38.3 bits (85), Expect = 0.11
Identities = 29/109 (26%), Positives = 38/109 (34%), Gaps = 6/109 (5%)
Query: 755 PGLCAPGRFRCVCGPGYRPAGEV--CADVDECAVRPPPCDQLCHNTDGSYDCLC---RTG 809
PG G VC P GE C + EC+ +P C Y C+C RTG
Sbjct: 109 PGFRLVGPSSMVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTG 168
Query: 810 YELDEDGANCRDVDECERDTHTCQQI-CSNTEGSYECSCEDGYEKRGDA 857
D+ + C+ E + CSCE G+ G A
Sbjct: 169 NRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAA 217
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.141 0.504
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 165,511,962
Number of Sequences: 224733
Number of extensions: 8896555
Number of successful extensions: 77364
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 648
Number of HSP's successfully gapped in prelim test: 602
Number of HSP's that attempted gapping in prelim test: 16629
Number of HSP's gapped (non-prelim): 18930
length of query: 860
length of database: 73,234,838
effective HSP length: 96
effective length of query: 764
effective length of database: 51,660,470
effective search space: 39468599080
effective search space used: 39468599080
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 69 (31.9 bits)
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